Cancer_type QTL_type tag_SNP LD SNP SNP_position Alleles Methylation_probe Methylation_position Probe_related_gene Beta t-stat Correlation_coefficient (r) p-value Traits LIHC cis rs11718455 0.591 rs6765212 chr3:43931484 C/T cg08738300 chr3:44038990 NA 0.37 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs600806 0.888 rs11102971 chr1:109872370 C/T cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.92 -0.3 7.78e-9 Intelligence (multi-trait analysis); LIHC cis rs700651 0.624 rs12105927 chr2:198937258 G/A cg03934865 chr2:198174659 NA 0.43 6.09 0.31 3.01e-9 Intracranial aneurysm; LIHC trans rs3780486 0.713 rs3780489 chr9:33129844 G/T cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs34172651 0.917 rs2059134 chr16:24816492 C/T cg00152838 chr16:24741724 TNRC6A 0.46 6.45 0.33 3.78e-10 Intelligence (multi-trait analysis); LIHC cis rs12887734 0.546 rs12885509 chr14:104273325 T/C cg08213375 chr14:104286397 PPP1R13B 0.54 9.36 0.45 1.08e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs1691799 0.899 rs1168294 chr12:66733988 T/C cg16791601 chr12:66731901 HELB -0.57 -13.85 -0.6 6.11e-35 White blood cell count (basophil); LIHC cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.14e-11 Alzheimer's disease; LIHC cis rs2295359 1.000 rs11209006 chr1:67619259 T/G cg12940439 chr1:67600707 NA 0.4 7.24 0.36 2.96e-12 Psoriasis; LIHC cis rs425277 1.000 rs262665 chr1:2083173 A/G cg24578937 chr1:2090814 PRKCZ 0.5 9.03 0.44 1.25e-17 Height; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.58 -8.31 -0.41 2.24e-15 Lymphocyte counts; LIHC cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg03452623 chr4:187889614 NA -0.32 -8.54 -0.42 4.48e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs3112357 1.000 rs3112355 chr7:135394680 C/T cg20392616 chr7:135392013 SLC13A4 0.39 6.53 0.33 2.38e-10 Plantar warts; LIHC cis rs9560113 1.000 rs9555810 chr13:112181437 C/G cg14154082 chr13:112174009 NA 0.29 6.21 0.32 1.52e-9 Menarche (age at onset); LIHC cis rs6466055 0.720 rs1204066 chr7:104971987 G/T cg04380332 chr7:105027541 SRPK2 0.38 7.28 0.37 2.26e-12 Schizophrenia; LIHC cis rs4237845 0.837 rs7954957 chr12:58299250 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.43 6.04 0.31 4e-9 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs11706117 chr3:134212526 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.15 -0.55 1.75e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.68 -0.42 1.69e-16 Lymphocyte counts; LIHC cis rs11969893 0.649 rs9390699 chr6:101306502 C/G cg12253828 chr6:101329408 ASCC3 0.95 12.16 0.55 1.6e-28 Economic and political preferences (immigration/crime); LIHC cis rs1165668 1.000 rs1165668 chr12:104317996 G/A cg21863207 chr12:104234989 NT5DC3 0.39 6.2 0.32 1.62e-9 Coronary heart disease (SNP X SNP interaction); LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg10755058 chr3:40428713 ENTPD3 -0.41 -7.14 -0.36 5.64e-12 Renal cell carcinoma; LIHC cis rs6570726 0.935 rs398060 chr6:145841515 C/T cg23711669 chr6:146136114 FBXO30 -0.53 -9.28 -0.45 1.93e-18 Lobe attachment (rater-scored or self-reported); LIHC trans rs116095464 0.510 rs10057501 chr5:239545 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.79 0.34 4.99e-11 Breast cancer; LIHC cis rs713477 0.678 rs4901566 chr14:55912663 C/A cg13175173 chr14:55914753 NA -0.29 -6.6 -0.34 1.53e-10 Pediatric bone mineral content (femoral neck); LIHC cis rs523522 0.962 rs12814055 chr12:120987391 G/A cg12219531 chr12:120966889 COQ5 0.68 13.4 0.59 3.38e-33 High light scatter reticulocyte count; LIHC cis rs9611519 0.929 rs4820423 chr22:41430338 A/T cg03806693 chr22:41940476 POLR3H -0.69 -7.72 -0.39 1.27e-13 Neuroticism; LIHC cis rs7772486 0.641 rs9390370 chr6:146357569 C/T cg23711669 chr6:146136114 FBXO30 0.57 8.75 0.43 1.01e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs703842 1.000 rs11172335 chr12:58175201 C/T cg18357645 chr12:58087776 OS9 -0.45 -6.97 -0.35 1.61e-11 Multiple sclerosis; LIHC cis rs703842 0.963 rs2069506 chr12:58142854 C/A cg18357645 chr12:58087776 OS9 -0.48 -7.24 -0.36 3.08e-12 Multiple sclerosis; LIHC cis rs72627509 0.904 rs12645070 chr4:57770106 G/A cg26694713 chr4:57773883 REST 0.73 10.24 0.48 1.2e-21 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs12477438 0.798 rs12468419 chr2:99579680 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.39 -0.49 3.79e-22 Chronic sinus infection; LIHC cis rs4803468 0.935 rs284660 chr19:41932084 G/T cg14132834 chr19:41945861 ATP5SL -0.44 -6.34 -0.32 7.31e-10 Height; LIHC cis rs9611565 0.546 rs132793 chr22:42063681 A/G cg06634786 chr22:41940651 POLR3H 0.72 7.28 0.37 2.35e-12 Vitiligo; LIHC cis rs1401999 0.966 rs4148585 chr3:183670642 A/G cg01324343 chr3:183735012 ABCC5 0.78 12.96 0.57 1.55e-31 Anterior chamber depth; LIHC cis rs2404602 0.735 rs2436996 chr15:76817420 C/T cg03037974 chr15:76606532 NA -0.63 -10.95 -0.51 4.07e-24 Blood metabolite levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02594498 chr15:22893147 CYFIP1 -0.38 -6.12 -0.31 2.62e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11167764 1.000 rs6580220 chr5:141480558 G/A cg23435118 chr5:141488016 NDFIP1 -0.44 -6.12 -0.31 2.61e-9 Crohn's disease; LIHC cis rs9916302 0.645 rs1053651 chr17:37822311 A/C cg07936489 chr17:37558343 FBXL20 -0.49 -7.53 -0.38 4.48e-13 Glomerular filtration rate (creatinine); LIHC cis rs12464559 0.522 rs11676866 chr2:152628858 G/C cg01189475 chr2:152685088 ARL5A 0.72 9.21 0.45 3.27e-18 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs17253792 0.822 rs80085988 chr14:56096173 A/G cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.866 rs6857892 chr4:120282696 G/T cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg00035636 chr13:21900591 NA 0.37 6.05 0.31 3.71e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg16434002 chr17:42200994 HDAC5 0.55 7.96 0.4 2.49e-14 Total body bone mineral density; LIHC cis rs67478160 0.619 rs11160761 chr14:104254856 A/T cg08213375 chr14:104286397 PPP1R13B 0.65 12.85 0.57 4.28e-31 Schizophrenia; LIHC cis rs7103648 0.569 rs11039266 chr11:47532395 T/G cg20307385 chr11:47447363 PSMC3 0.9 12.67 0.57 2.05e-30 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg16049864 chr8:95962084 TP53INP1 -0.63 -12.13 -0.55 2.17e-28 Type 2 diabetes; LIHC cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg10802521 chr3:52805072 NEK4 -0.44 -7.36 -0.37 1.35e-12 Bipolar disorder; LIHC cis rs62380364 0.565 rs13158247 chr5:88030670 C/T cg22951263 chr5:87985283 NA -0.39 -6.8 -0.35 4.61e-11 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.816 rs7027263 chr9:111699569 G/A cg05043794 chr9:111880884 C9orf5 -0.29 -6.65 -0.34 1.15e-10 Menarche (age at onset); LIHC cis rs4474465 0.850 rs4597089 chr11:78262244 A/G cg27205649 chr11:78285834 NARS2 0.42 6.39 0.33 5.44e-10 Alzheimer's disease (survival time); LIHC cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg11764359 chr7:65958608 NA 0.69 9.44 0.45 6.05e-19 Aortic root size; LIHC cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs9918079 0.560 rs4698409 chr4:15659766 G/A cg04067612 chr4:15429572 C1QTNF7 -0.27 -5.76 -0.3 1.88e-8 Obesity-related traits; LIHC cis rs7662987 0.517 rs1377689 chr4:100021787 A/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs6088580 0.634 rs6058051 chr20:33044862 G/A cg08999081 chr20:33150536 PIGU 0.67 13.33 0.58 6.18e-33 Glomerular filtration rate (creatinine); LIHC cis rs11031096 0.727 rs12290828 chr11:4144867 C/G cg18678763 chr11:4115507 RRM1 -0.53 -8.05 -0.4 1.36e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6912958 0.515 rs381782 chr6:88040649 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.52 0.53 3.59e-26 Monocyte percentage of white cells; LIHC cis rs7904368 0.806 rs4612698 chr10:16855070 C/A cg14835575 chr10:16859367 RSU1 0.65 8.95 0.44 2.24e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg18306943 chr3:40428807 ENTPD3 0.39 6.51 0.33 2.63e-10 Renal cell carcinoma; LIHC trans rs7618501 0.521 rs868891 chr3:49949071 A/G cg21659725 chr3:3221576 CRBN 0.56 8.16 0.4 6.32e-15 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg08888203 chr3:10149979 C3orf24 0.54 6.67 0.34 1.04e-10 Alzheimer's disease; LIHC cis rs2832191 0.671 rs2409332 chr21:30512779 G/A cg08807101 chr21:30365312 RNF160 -0.42 -5.96 -0.31 6.43e-9 Dental caries; LIHC cis rs12765878 0.675 rs3752946 chr10:105670849 A/T cg11005552 chr10:105648138 OBFC1 0.38 6.0 0.31 5.1e-9 Coronary artery disease; LIHC cis rs3790844 0.876 rs3790845 chr1:200006861 C/T cg07208853 chr1:200005219 NR5A2 0.42 9.12 0.44 6.64e-18 Pancreatic cancer; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs2070488 0.965 rs35091896 chr3:38443320 G/A cg24069376 chr3:38537580 EXOG 0.42 7.72 0.39 1.3e-13 Electrocardiographic conduction measures; LIHC cis rs1005277 0.505 rs200910 chr10:38108176 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.6 -0.56 3.51e-30 Extrinsic epigenetic age acceleration; LIHC cis rs4586057 0.514 rs7896973 chr10:92650797 A/G cg14313238 chr10:92632228 RPP30 0.37 6.22 0.32 1.48e-9 Economic and political preferences (time); LIHC cis rs7085104 0.632 rs7096475 chr10:104609676 A/G cg04362960 chr10:104952993 NT5C2 0.39 5.86 0.3 1.09e-8 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.85 0.3 1.14e-8 Aortic root size; LIHC cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg05555928 chr11:63887634 MACROD1 0.56 7.4 0.37 1.08e-12 Mean platelet volume; LIHC cis rs2836950 0.565 rs2836942 chr21:40591381 A/G cg11890956 chr21:40555474 PSMG1 -0.47 -7.68 -0.38 1.68e-13 Menarche (age at onset); LIHC cis rs116095464 0.558 rs10065584 chr5:253997 G/A cg22857025 chr5:266934 NA -1.56 -16.35 -0.66 8.71e-45 Breast cancer; LIHC cis rs6500602 0.702 rs1051308 chr16:4560301 A/G cg04083430 chr16:4736063 MGRN1 0.43 5.88 0.3 9.8e-9 Schizophrenia; LIHC cis rs1215050 0.791 rs783960 chr4:98893437 A/G cg05340658 chr4:99064831 C4orf37 -0.39 -5.78 -0.3 1.67e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.17 -0.44 4.56e-18 Bipolar disorder; LIHC cis rs11991744 0.681 rs11784192 chr8:124664167 T/C cg22342100 chr8:124666123 KLHL38 -0.39 -6.19 -0.32 1.74e-9 Electrocardiographic traits; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg11494091 chr17:61959527 GH2 0.44 8.17 0.4 6.08e-15 Prudent dietary pattern; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg10150615 chr22:24372951 LOC391322 -0.53 -7.69 -0.38 1.56e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1552244 0.744 rs6763366 chr3:10033544 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.66 -10.33 -0.49 5.79e-22 Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03150409 chr4:1892317 WHSC1 -0.63 -8.87 -0.43 4.02e-17 Lung function (FEV1/FVC); LIHC cis rs7937890 0.900 rs7118682 chr11:14274550 T/G cg02251663 chr11:14281053 SPON1 0.46 6.34 0.32 7.34e-10 Mitochondrial DNA levels; LIHC cis rs11212737 0.714 rs2640768 chr11:108520632 C/A cg22776369 chr11:108536276 DDX10 0.38 6.21 0.32 1.56e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg21373526 chr11:82782794 RAB30 0.4 6.65 0.34 1.15e-10 Longevity; LIHC cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs13108904 0.539 rs13145722 chr4:1338422 T/A cg00684032 chr4:1343700 KIAA1530 0.58 8.55 0.42 4.15e-16 Obesity-related traits; LIHC cis rs4660261 0.526 rs2040950 chr1:44315113 G/C cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs921968 0.643 rs832806 chr2:219473914 A/T cg02985541 chr2:219472218 PLCD4 0.43 7.82 0.39 6.76e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs11146838 1 rs11146838 chr10:39149977 A/T cg00409905 chr10:38381863 ZNF37A -0.48 -7.57 -0.38 3.58e-13 Breast cancer; LIHC cis rs9905704 0.647 rs9898048 chr17:57108543 C/T cg12560992 chr17:57184187 TRIM37 0.65 9.85 0.47 2.63e-20 Testicular germ cell tumor; LIHC cis rs56011263 0.687 rs4690188 chr4:703930 G/C cg17689763 chr4:710664 PCGF3 -0.73 -10.44 -0.49 2.5e-22 White blood cell count; LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg20607798 chr8:58055168 NA 0.66 8.34 0.41 1.86e-15 Developmental language disorder (linguistic errors); LIHC cis rs7927771 0.524 rs7943464 chr11:47886639 T/A cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.34e-24 Subjective well-being; LIHC cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.45 6.65 0.34 1.15e-10 Schizophrenia; LIHC cis rs3770081 1.000 rs2241437 chr2:86360573 A/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.43 6.06 0.31 3.67e-9 Facial emotion recognition (sad faces); LIHC cis rs597539 0.552 rs10896384 chr11:68720011 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.77 -10.8 -0.5 1.41e-23 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6840360 0.571 rs55808836 chr4:152554991 C/T cg22705602 chr4:152727874 NA -0.32 -6.26 -0.32 1.17e-9 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg14671364 chr1:107599128 PRMT6 -0.45 -6.46 -0.33 3.6e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9399135 0.967 rs6569990 chr6:135365818 C/T cg22676075 chr6:135203613 NA 0.4 6.36 0.33 6.58e-10 Red blood cell count; LIHC cis rs919433 0.680 rs788023 chr2:198283305 T/C cg10820045 chr2:198174542 NA 0.56 9.11 0.44 7.29e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs853679 0.517 rs9348797 chr6:28137533 G/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs2243480 0.708 rs13242216 chr7:65898277 T/C cg12463550 chr7:65579703 CRCP 0.59 5.93 0.31 7.32e-9 Diabetic kidney disease; LIHC cis rs1046896 0.520 rs8074086 chr17:80818460 A/C cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.44 0.37 8.01e-13 Glycated hemoglobin levels; LIHC cis rs9399135 0.967 rs6929661 chr6:135328792 G/A cg22676075 chr6:135203613 NA 0.38 6.24 0.32 1.32e-9 Red blood cell count; LIHC cis rs694739 1.000 rs499425 chr11:64105929 A/G cg23796481 chr11:64053134 BAD;GPR137 -0.59 -8.47 -0.42 7.29e-16 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs8060686 0.545 rs74629553 chr16:68176415 C/A cg05110241 chr16:68378359 PRMT7 -0.63 -6.85 -0.35 3.34e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg02290350 chr8:58132656 NA 0.5 10.22 0.48 1.43e-21 Developmental language disorder (linguistic errors); LIHC cis rs55665837 1.000 rs11023224 chr11:14457739 G/A cg19336497 chr11:14380999 RRAS2 -0.44 -7.99 -0.4 2.15e-14 Vitamin D levels; LIHC cis rs1030877 0.889 rs2576746 chr2:105909559 G/A cg02079111 chr2:105885981 TGFBRAP1 0.67 12.22 0.55 1.01e-28 Obesity-related traits; LIHC cis rs12477438 0.765 rs62156363 chr2:99693324 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.54 -0.38 4.32e-13 Chronic sinus infection; LIHC cis rs7216064 1.000 rs59950564 chr17:65860859 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs72627123 0.530 rs79371463 chr14:74474856 T/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 9.49 0.46 4.07e-19 Morning vs. evening chronotype; LIHC cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.12 -0.44 6.77e-18 Bipolar disorder; LIHC cis rs8180040 1.000 rs295461 chr3:47368010 T/C cg16586182 chr3:47516702 SCAP -0.54 -9.83 -0.47 2.93e-20 Colorectal cancer; LIHC cis rs4423214 0.840 rs4435028 chr11:71183690 C/A cg05163923 chr11:71159392 DHCR7 -0.6 -7.9 -0.39 3.79e-14 Vitamin D levels; LIHC cis rs7613875 0.620 rs17657664 chr3:50032008 T/G cg05623727 chr3:50126028 RBM5 0.34 5.89 0.3 9.04e-9 Body mass index; LIHC cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs2838833 chr21:46665160 C/T cg11663144 chr21:46675770 NA -0.33 -6.15 -0.32 2.13e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7020830 0.898 rs2790063 chr9:37287405 G/A cg14294708 chr9:37120828 ZCCHC7 1.04 21.33 0.76 8.26e-65 Schizophrenia; LIHC cis rs77106637 1.000 rs11605166 chr11:72669777 T/C cg03713592 chr11:72463424 ARAP1 0.75 6.32 0.32 8.16e-10 Type 2 diabetes; LIHC cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 7.23 0.36 3.11e-12 Platelet count; LIHC trans rs5756813 0.727 rs58765732 chr22:38160794 A/C cg19894588 chr14:64061835 NA -0.63 -8.75 -0.43 9.67e-17 Optic cup area;Vertical cup-disc ratio; LIHC cis rs2730245 1.000 rs2252502 chr7:158738634 G/C cg24397884 chr7:158709396 WDR60 -0.41 -6.18 -0.32 1.85e-9 Height; LIHC cis rs9303401 0.614 rs8081058 chr17:57160513 G/C cg25039879 chr17:56429692 SUPT4H1 0.77 9.0 0.44 1.63e-17 Cognitive test performance; LIHC cis rs7116495 0.609 rs2155142 chr11:71642524 A/G cg26138937 chr11:71823887 C11orf51 1.1 9.53 0.46 2.92e-19 Severe influenza A (H1N1) infection; LIHC cis rs3849570 0.615 rs35779564 chr3:81982771 G/A cg07356753 chr3:81810745 GBE1 -0.46 -7.12 -0.36 6.57e-12 Waist circumference;Body mass index; LIHC cis rs172166 0.769 rs149965 chr6:28018689 T/A cg23485639 chr6:28045615 ZNF165 0.38 5.8 0.3 1.47e-8 Cardiac Troponin-T levels; LIHC trans rs1488564 1.000 rs1488564 chr3:173453868 A/G cg14450231 chr5:172199425 DUSP1 0.4 6.06 0.31 3.53e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14395634 chr11:65626208 CFL1 0.42 6.04 0.31 4.04e-9 Cognitive function; LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg09455208 chr3:40491958 NA 0.42 8.51 0.42 5.4e-16 Renal cell carcinoma; LIHC cis rs9517302 0.615 rs7983522 chr13:99098055 C/T cg22223119 chr13:99095684 FARP1 -0.62 -9.54 -0.46 2.88e-19 Obesity-related traits; LIHC cis rs3796619 0.503 rs13147452 chr4:1078124 G/A cg13468214 chr4:1046988 NA -0.36 -6.68 -0.34 9.75e-11 Recombination rate (males); LIHC cis rs9858542 0.953 rs9837341 chr3:49664767 A/G cg03060546 chr3:49711283 APEH -0.58 -7.56 -0.38 3.86e-13 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs8077889 0.871 rs8081101 chr17:41904332 C/T cg26893861 chr17:41843967 DUSP3 0.93 10.72 0.5 2.51e-23 Triglycerides; LIHC cis rs16854884 0.632 rs35362423 chr3:143687441 C/A cg06585982 chr3:143692056 C3orf58 0.58 7.79 0.39 8.18e-14 Economic and political preferences (feminism/equality); LIHC trans rs4644158 1.000 rs4644158 chr7:101536726 G/T cg09627607 chr7:23028562 FAM126A 0.59 6.23 0.32 1.4e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2742417 0.603 rs2742449 chr3:45764544 T/C cg04837898 chr3:45731254 SACM1L -0.52 -8.63 -0.42 2.3e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs10751667 0.600 rs7950955 chr11:1011490 G/A cg10932868 chr11:921992 NA 0.31 5.8 0.3 1.52e-8 Alzheimer's disease (late onset); LIHC cis rs738322 0.967 rs4383 chr22:38570927 C/G cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs3806843 1.000 rs2337985 chr5:140157861 T/C cg19875535 chr5:140030758 IK 0.37 5.94 0.31 7.05e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2274273 0.905 rs8007944 chr14:55576816 A/C cg01864836 chr14:55583639 NA -0.43 -8.46 -0.42 7.86e-16 Protein biomarker; LIHC cis rs2204008 0.744 rs11182316 chr12:38499552 G/A cg26384229 chr12:38710491 ALG10B 0.96 12.33 0.55 3.75e-29 Bladder cancer; LIHC cis rs17685 0.753 rs4732542 chr7:75663203 A/G cg04610667 chr7:75704037 NA -0.32 -5.97 -0.31 5.9e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7309 0.935 rs10930013 chr2:162070325 G/A cg22496339 chr2:162101262 NA 0.81 13.56 0.59 7.91e-34 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs7927771 0.524 rs9633830 chr11:47849470 T/G cg20307385 chr11:47447363 PSMC3 0.76 11.4 0.52 1.02e-25 Subjective well-being; LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.931 rs13168670 chr5:140146899 T/C cg19875535 chr5:140030758 IK 0.37 6.11 0.31 2.66e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2404602 0.716 rs56351018 chr15:76824591 T/C cg03037974 chr15:76606532 NA 0.79 15.99 0.65 2.33e-43 Blood metabolite levels; LIHC cis rs7772486 0.875 rs9376975 chr6:146355581 T/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg06481639 chr22:41940642 POLR3H -0.7 -7.19 -0.36 4.06e-12 Vitiligo; LIHC cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.04 0.31 3.93e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs561341 0.941 rs4625780 chr17:30249214 A/C cg20587970 chr11:113659929 NA -0.58 -6.64 -0.34 1.26e-10 Hip circumference adjusted for BMI; LIHC cis rs4862750 0.872 rs4862748 chr4:187877388 C/T cg03452623 chr4:187889614 NA 0.25 6.54 0.33 2.18e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7116495 0.609 rs10793014 chr11:71698838 A/G cg10381502 chr11:71823885 C11orf51 -1.0 -8.24 -0.41 3.84e-15 Severe influenza A (H1N1) infection; LIHC cis rs11229555 0.609 rs7927730 chr11:58187906 G/A cg15696309 chr11:58395628 NA -0.64 -7.47 -0.37 6.57e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs12928939 0.517 rs12149325 chr16:71968147 G/C cg03805757 chr16:71968109 PKD1L3 -0.93 -12.67 -0.57 2.02e-30 Post bronchodilator FEV1; LIHC cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg08392591 chr16:89556376 ANKRD11 0.4 5.99 0.31 5.31e-9 Multiple myeloma (IgH translocation); LIHC cis rs62458065 0.713 rs28421905 chr7:32489501 G/A cg06627557 chr7:32535165 LSM5;AVL9 -0.59 -5.71 -0.3 2.43e-8 Metabolite levels (HVA/MHPG ratio); LIHC cis rs8056893 0.885 rs7199750 chr16:68351859 C/G cg02226672 chr16:68398533 SMPD3 0.41 5.87 0.3 1.02e-8 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs1577917 0.874 rs1838954 chr6:86565478 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC cis rs9399135 0.967 rs1023179 chr6:135343829 T/A cg22676075 chr6:135203613 NA 0.4 6.41 0.33 4.74e-10 Red blood cell count; LIHC cis rs4268898 0.610 rs72791170 chr2:24449776 C/T cg06627628 chr2:24431161 ITSN2 -0.73 -9.76 -0.47 5.02e-20 Asthma; LIHC cis rs2839186 0.721 rs3788252 chr21:47661235 C/T cg11766577 chr21:47581405 C21orf56 -0.45 -7.25 -0.37 2.77e-12 Testicular germ cell tumor; LIHC cis rs7927592 0.912 rs55767696 chr11:68375120 C/G cg20283391 chr11:68216788 NA -0.51 -7.56 -0.38 3.67e-13 Total body bone mineral density; LIHC cis rs12101261 1.000 rs12101261 chr14:81451229 C/T cg06600135 chr14:81408086 NA 0.36 6.05 0.31 3.83e-9 Graves' disease; LIHC cis rs9503598 0.644 rs9503593 chr6:3430787 T/C cg00476032 chr6:3446245 SLC22A23 0.34 6.44 0.33 4.13e-10 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg05896524 chr21:47604654 C21orf56 0.51 8.13 0.4 7.84e-15 Testicular germ cell tumor; LIHC cis rs2075371 1.000 rs1421486 chr7:133985196 T/C cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC cis rs1200821 0.529 rs2505707 chr10:37801254 T/C cg25427524 chr10:38739819 LOC399744 -0.46 -7.84 -0.39 5.97e-14 Hemostatic factors and hematological phenotypes; LIHC cis rs9916302 0.861 rs8079590 chr17:37426201 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.49 -0.59 1.55e-33 Glomerular filtration rate (creatinine); LIHC cis rs523522 0.962 rs12309824 chr12:120990582 A/C cg27279351 chr12:120934652 DYNLL1 0.66 11.79 0.54 3.63e-27 High light scatter reticulocyte count; LIHC cis rs7909074 0.966 rs4245614 chr10:45397007 C/T cg05187965 chr10:45406764 TMEM72 -0.26 -6.56 -0.33 1.96e-10 Mean corpuscular volume; LIHC cis rs1494950 1.000 rs2643082 chr4:14995227 C/T cg12377275 chr4:15005593 CPEB2 -0.79 -6.68 -0.34 9.6e-11 Political ideology; LIHC cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg06238570 chr21:40685208 BRWD1 0.59 7.03 0.36 1.12e-11 Cognitive function; LIHC cis rs17152411 0.895 rs61872119 chr10:126583534 A/G cg07906193 chr10:126599966 NA 0.43 6.94 0.35 1.93e-11 Height; LIHC trans rs1814175 0.571 rs12294066 chr11:49738287 C/T cg03929089 chr4:120376271 NA -0.86 -16.84 -0.67 9.09e-47 Height; LIHC cis rs7116495 1.000 rs675185 chr11:71775572 T/G cg26138937 chr11:71823887 C11orf51 -0.79 -7.81 -0.39 6.89e-14 Severe influenza A (H1N1) infection; LIHC cis rs8017423 0.934 rs11159952 chr14:90684874 T/C cg14092571 chr14:90743983 NA -0.37 -5.89 -0.3 9.22e-9 Mortality in heart failure; LIHC trans rs6600671 1.000 rs1986111 chr1:121204788 C/T cg09829573 chr1:144692074 NBPF9 -0.41 -7.33 -0.37 1.72e-12 Hip geometry; LIHC cis rs11676348 0.846 rs13009946 chr2:219007752 A/C cg00012203 chr2:219082015 ARPC2 -0.48 -6.93 -0.35 2.08e-11 Ulcerative colitis; LIHC cis rs17021463 0.673 rs1426566 chr4:95292086 T/G cg11021082 chr4:95130006 SMARCAD1 0.44 7.59 0.38 3e-13 Testicular germ cell tumor; LIHC cis rs2580764 0.565 rs7562292 chr2:55230219 C/T cg09592903 chr2:55203963 RTN4 -0.72 -13.47 -0.59 1.86e-33 Mean platelet volume; LIHC cis rs2050392 1.000 rs7077496 chr10:30692028 G/A cg25182066 chr10:30743637 MAP3K8 0.43 7.02 0.36 1.18e-11 Inflammatory bowel disease; LIHC cis rs921968 0.565 rs62191658 chr2:219630294 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2439831 0.867 rs28461955 chr15:43661459 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.18 0.52 5.88e-25 Lung cancer in ever smokers; LIHC cis rs919433 0.617 rs13018267 chr2:198545592 G/C cg00792783 chr2:198669748 PLCL1 -0.43 -6.26 -0.32 1.15e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8027181 1.000 rs12900863 chr15:73094671 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.47 7.18 0.36 4.5e-12 Triglyceride levels; LIHC cis rs2439831 0.867 rs76542740 chr15:43891512 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.58 7.16 0.36 4.97e-12 Lung cancer in ever smokers; LIHC cis rs17685 0.753 rs10952840 chr7:75772878 C/T cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8062405 1.000 rs28403629 chr16:28854769 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10744422 0.858 rs12426809 chr12:123327143 C/T cg22842854 chr12:123319900 HIP1R -0.65 -8.57 -0.42 3.5e-16 Schizophrenia; LIHC cis rs4834770 1.000 rs878374 chr4:120237564 A/G cg09307838 chr4:120376055 NA 0.42 6.24 0.32 1.33e-9 Blood protein levels; LIHC cis rs3106136 0.678 rs28437833 chr4:95280510 A/T cg11021082 chr4:95130006 SMARCAD1 0.34 5.87 0.3 1.04e-8 Capecitabine sensitivity; LIHC cis rs8180040 0.767 rs11920853 chr3:47308183 G/A cg16586182 chr3:47516702 SCAP 0.51 8.95 0.44 2.33e-17 Colorectal cancer; LIHC cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg13397359 chr6:42928475 GNMT -0.77 -10.93 -0.51 4.88e-24 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg11062466 chr8:58055876 NA 0.5 7.42 0.37 9.65e-13 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.680 rs4728467 chr7:139120562 G/A cg07862535 chr7:139043722 LUC7L2 0.66 11.19 0.52 5.49e-25 Diisocyanate-induced asthma; LIHC trans rs11098499 0.909 rs10002083 chr4:120311152 C/T cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs4409675 0.576 rs6703851 chr1:28237556 G/A cg23691781 chr1:28212827 C1orf38 0.31 7.01 0.35 1.29e-11 Corneal astigmatism; LIHC cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg22105103 chr4:187893119 NA 0.34 8.91 0.43 3.02e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg00106254 chr7:1943704 MAD1L1 -0.46 -7.59 -0.38 3.1400000000000003e-13 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.87 0.39 4.61e-14 Prudent dietary pattern; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg02993280 chr1:107599747 PRMT6 0.62 9.22 0.45 3.22e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6964587 0.900 rs11984136 chr7:91766953 T/C cg17063962 chr7:91808500 NA 1.05 21.54 0.76 1.19e-65 Breast cancer; LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg14004847 chr7:1930337 MAD1L1 -0.47 -6.8 -0.35 4.62e-11 Bipolar disorder and schizophrenia; LIHC cis rs13064411 0.696 rs1486894 chr3:113211513 G/A cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.27 -0.45 2.09e-18 Bipolar disorder; LIHC cis rs7715806 0.500 rs72633982 chr5:75001321 C/T cg19683494 chr5:74908142 NA 0.68 7.91 0.39 3.55e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9733 0.526 rs11204696 chr1:150658721 T/C cg15448220 chr1:150897856 SETDB1 0.43 6.74 0.34 6.71e-11 Tonsillectomy; LIHC cis rs1005277 0.522 rs7090858 chr10:38003670 A/C cg25427524 chr10:38739819 LOC399744 0.63 12.23 0.55 8.81e-29 Extrinsic epigenetic age acceleration; LIHC cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg13397359 chr6:42928475 GNMT -0.48 -7.08 -0.36 8.05e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs950169 0.922 rs4586394 chr15:84822385 G/A cg17507749 chr15:85114479 UBE2QP1 -0.68 -7.31 -0.37 1.89e-12 Schizophrenia; LIHC cis rs11734570 0.581 rs73808504 chr4:38600593 T/C cg18361445 chr4:38666374 KLF3;FLJ13197 0.51 6.97 0.35 1.68e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2404602 0.735 rs1607017 chr15:76726465 G/T cg03037974 chr15:76606532 NA -0.63 -11.06 -0.51 1.65e-24 Blood metabolite levels; LIHC cis rs2290416 0.892 rs77370907 chr8:144664975 G/C cg26536354 chr8:144654954 C8orf73 0.56 6.1 0.31 2.91e-9 Attention deficit hyperactivity disorder; LIHC cis rs9814567 1.000 rs6766897 chr3:134191303 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.57 -10.42 -0.49 3.03e-22 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12220238 1.000 rs7081350 chr10:75990328 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.76 0.34 5.8e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg05552183 chr6:42928497 GNMT 0.81 11.99 0.54 6.6e-28 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs1814175 0.645 rs10769605 chr11:49713723 A/G cg15704280 chr7:45808275 SEPT13 -0.97 -20.66 -0.75 4.12e-62 Height; LIHC cis rs8072100 0.967 rs4794058 chr17:45597098 C/T cg08085267 chr17:45401833 C17orf57 0.4 6.01 0.31 4.72e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1552244 0.832 rs3732968 chr3:10013273 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.71 0.5 2.81e-23 Alzheimer's disease; LIHC cis rs4934494 0.681 rs34591435 chr10:91481448 A/G cg19698084 chr10:91461284 KIF20B -0.47 -6.35 -0.32 6.84e-10 Red blood cell count; LIHC cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg18404041 chr3:52824283 ITIH1 -0.5 -8.24 -0.41 3.83e-15 Intelligence (multi-trait analysis); LIHC cis rs875971 0.545 rs316316 chr7:65614257 C/T cg11764359 chr7:65958608 NA -0.51 -6.95 -0.35 1.87e-11 Aortic root size; LIHC cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 11.6 0.53 1.85e-26 Alzheimer's disease; LIHC cis rs7107174 1.000 rs2511170 chr11:77980582 A/G cg02023728 chr11:77925099 USP35 0.49 9.46 0.46 5.24e-19 Testicular germ cell tumor; LIHC cis rs8067354 0.645 rs1874548 chr17:57841357 A/G cg13753209 chr17:57696993 CLTC 0.76 12.15 0.55 1.75e-28 Hemoglobin concentration; LIHC cis rs7512552 0.698 rs12028001 chr1:150407820 C/T cg15654264 chr1:150340011 RPRD2 0.68 11.21 0.52 4.66e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg21280719 chr6:42927975 GNMT -0.31 -7.04 -0.36 1.05e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6087685 1.000 rs10747514 chr20:33775369 G/A cg08999081 chr20:33150536 PIGU 0.39 5.71 0.3 2.42e-8 Venous thromboembolism; LIHC cis rs6545883 0.791 rs4672445 chr2:61655008 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.56 -0.38 3.66e-13 Tuberculosis; LIHC cis rs9640161 0.750 rs3800780 chr7:150027284 C/A cg10018233 chr7:150070692 REPIN1 0.51 7.96 0.4 2.48e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs8017423 0.935 rs11624246 chr14:90734826 A/G cg14092571 chr14:90743983 NA 0.46 7.32 0.37 1.8e-12 Mortality in heart failure; LIHC cis rs847649 0.621 rs2222539 chr7:102674786 G/A cg18108683 chr7:102477205 FBXL13 0.39 5.9 0.3 8.63e-9 Morning vs. evening chronotype; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14450231 chr5:172199425 DUSP1 0.47 6.71 0.34 8.31e-11 Lung function (FEV1/FVC); LIHC cis rs1401999 0.966 rs2292998 chr3:183663833 T/C cg01324343 chr3:183735012 ABCC5 0.77 13.18 0.58 2.42e-32 Anterior chamber depth; LIHC cis rs2204008 0.818 rs7313608 chr12:38383428 C/A cg26384229 chr12:38710491 ALG10B -0.58 -8.33 -0.41 1.98e-15 Bladder cancer; LIHC cis rs9790314 0.846 rs7636941 chr3:160993928 A/G cg03342759 chr3:160939853 NMD3 -0.82 -13.54 -0.59 9.4e-34 Morning vs. evening chronotype; LIHC cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg25894440 chr7:65020034 NA -0.53 -6.04 -0.31 4.05e-9 Diabetic kidney disease; LIHC trans rs75804782 0.641 rs72983861 chr2:239326126 G/A cg01134436 chr17:81009848 B3GNTL1 0.77 6.43 0.33 4.19e-10 Morning vs. evening chronotype;Chronotype; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01198024 chr21:33672713 MRAP -0.45 -6.11 -0.31 2.78e-9 Lung function (FEV1/FVC); LIHC cis rs831571 0.955 rs35837 chr3:64013249 T/C cg16258503 chr3:63850278 ATXN7;THOC7 -0.56 -6.96 -0.35 1.8e-11 Type 2 diabetes; LIHC cis rs7582180 0.629 rs12612809 chr2:100951616 G/T cg14675211 chr2:100938903 LONRF2 0.54 8.51 0.42 5.7e-16 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg21782813 chr7:2030301 MAD1L1 0.43 7.44 0.37 8.26e-13 Bipolar disorder and schizophrenia; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg14318942 chr4:114683204 CAMK2D 0.45 6.25 0.32 1.21e-9 Migraine with aura; LIHC trans rs9354352 0.791 rs4710306 chr6:66700271 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.6 -9.34 -0.45 1.27e-18 Initial pursuit acceleration in psychotic disorders; LIHC cis rs12887734 0.524 rs17791722 chr14:104286210 C/T cg01849466 chr14:104193079 ZFYVE21 -0.39 -5.91 -0.3 8.37e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.71 0.38 1.37e-13 Intelligence (multi-trait analysis); LIHC cis rs6089829 0.962 rs3746749 chr20:61667333 T/C cg03213289 chr20:61660250 NA 0.5 8.92 0.43 2.84e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs2841277 0.708 rs28454709 chr14:105405942 G/A cg15352829 chr14:105391018 PLD4 -0.43 -9.22 -0.45 3.04e-18 Rheumatoid arthritis; LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg21782813 chr7:2030301 MAD1L1 0.56 10.19 0.48 1.78e-21 Bipolar disorder and schizophrenia; LIHC cis rs12497850 0.765 rs12487580 chr3:49182932 G/A cg16497277 chr3:49208875 KLHDC8B -0.48 -5.86 -0.3 1.09e-8 Parkinson's disease; LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg03721293 chr16:90014378 DEF8 0.36 6.25 0.32 1.19e-9 Skin colour saturation; LIHC cis rs7772486 0.875 rs9322048 chr6:146400439 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.77 0.3 1.82e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9948 1.000 rs62152793 chr2:97484948 C/T cg01990225 chr2:97406019 LMAN2L -0.66 -6.24 -0.32 1.32e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs3741404 0.791 rs2282491 chr11:63918373 T/C cg04317338 chr11:64019027 PLCB3 0.49 6.74 0.34 6.73e-11 Platelet count; LIHC cis rs2842992 0.724 rs4709368 chr6:160204127 C/T cg19482086 chr6:160211437 TCP1;MRPL18 -0.64 -12.06 -0.55 3.91e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs35110281 0.517 rs11089020 chr21:44939991 C/T cg04455712 chr21:45112962 RRP1B 0.4 6.52 0.33 2.52e-10 Mean corpuscular volume; LIHC cis rs4845570 0.850 rs4504897 chr1:151766851 T/A cg07092448 chr1:151763213 TDRKH 0.94 17.06 0.68 1.14e-47 Coronary artery disease; LIHC trans rs4650994 0.544 rs6682815 chr1:178501109 T/C cg05059571 chr16:84539110 KIAA1609 -0.41 -7.02 -0.35 1.2e-11 HDL cholesterol levels;HDL cholesterol; LIHC trans rs2727020 0.615 rs10128582 chr11:49447424 C/T cg03929089 chr4:120376271 NA -0.84 -16.28 -0.66 1.57e-44 Coronary artery disease; LIHC cis rs10876993 0.928 rs1628552 chr12:58082142 C/T cg18357645 chr12:58087776 OS9 0.52 8.54 0.42 4.54e-16 Celiac disease or Rheumatoid arthritis; LIHC trans rs7395662 0.591 rs10838972 chr11:48611400 A/G cg03929089 chr4:120376271 NA -0.4 -6.09 -0.31 3.02e-9 HDL cholesterol; LIHC cis rs7619427 1.000 rs7624393 chr3:44066045 C/A cg24966902 chr3:44043705 NA 0.56 7.76 0.39 9.6e-14 Schizophrenia; LIHC cis rs7267979 1.000 rs2258879 chr20:25279213 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7264396 0.635 rs6060720 chr20:34548336 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.56 -0.5 9.76e-23 Total cholesterol levels; LIHC cis rs807029 0.758 rs807027 chr10:102764607 T/A cg17130504 chr10:102756923 LZTS2 0.45 6.05 0.31 3.9e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg13012494 chr21:47604986 C21orf56 0.39 6.17 0.32 1.96e-9 Testicular germ cell tumor; LIHC cis rs7582180 0.764 rs13001423 chr2:100925340 A/G cg14675211 chr2:100938903 LONRF2 0.51 8.05 0.4 1.42e-14 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.636 rs10839275 chr11:49438962 T/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.56 -0.73 1.06e-57 Coronary artery disease; LIHC cis rs10503871 0.690 rs7812836 chr8:30352258 A/G cg26383811 chr8:30366931 RBPMS -0.39 -6.98 -0.35 1.52e-11 Metabolite levels (X-11787); LIHC cis rs17345786 0.511 rs12639028 chr3:101346033 G/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.68 10.89 0.51 6.48e-24 Colonoscopy-negative controls vs population controls; LIHC trans rs1973993 0.903 rs2038646 chr1:96940371 C/G cg10631902 chr5:14652156 NA 0.34 8.44 0.42 9.13e-16 Weight; LIHC cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.1 -0.48 3.53e-21 Platelet count; LIHC cis rs17106184 0.892 rs59318346 chr1:51190932 C/A cg07174182 chr1:51127561 FAF1 -0.64 -7.3 -0.37 2.04e-12 Type 2 diabetes; LIHC cis rs11674184 0.743 rs12470971 chr2:11725241 A/G cg07314298 chr2:11723111 GREB1 0.65 12.72 0.57 1.24e-30 Endometriosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16978263 chr3:160118452 SMC4;IFT80 0.49 7.28 0.37 2.37e-12 Cognitive function; LIHC cis rs7618501 0.521 rs7615206 chr3:49937505 T/C cg05623727 chr3:50126028 RBM5 0.35 5.88 0.3 9.73e-9 Intelligence (multi-trait analysis); LIHC cis rs600806 0.778 rs2140923 chr1:110004990 C/T cg10127483 chr1:110009974 SYPL2 0.5 6.23 0.32 1.33e-9 Intelligence (multi-trait analysis); LIHC cis rs7107174 1.000 rs2510055 chr11:77961912 C/T cg02023728 chr11:77925099 USP35 0.49 9.3 0.45 1.74e-18 Testicular germ cell tumor; LIHC cis rs8017423 0.967 rs6575120 chr14:90725094 C/T cg14092571 chr14:90743983 NA -0.39 -6.03 -0.31 4.21e-9 Mortality in heart failure; LIHC cis rs7614311 0.731 rs56263032 chr3:63863022 G/A cg22134162 chr3:63841271 THOC7 -0.55 -6.14 -0.31 2.34e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs67311347 1.000 rs1466236 chr3:40462162 C/T cg24209194 chr3:40518798 ZNF619 0.45 6.6 0.34 1.56e-10 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg16822855 chr3:40428330 ENTPD3 0.35 6.4 0.33 4.99e-10 Renal cell carcinoma; LIHC cis rs2153535 0.580 rs6597330 chr6:8492076 T/C cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs9948 0.655 rs78424221 chr2:97410399 A/G cg01990225 chr2:97406019 LMAN2L -0.81 -6.32 -0.32 8.31e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs8114671 0.836 rs6060165 chr20:33619480 A/C cg07148914 chr20:33460835 GGT7 -0.54 -8.34 -0.41 1.86e-15 Height; LIHC cis rs2153535 0.601 rs2015281 chr6:8539673 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.44 0.53 7.27e-26 Motion sickness; LIHC cis rs17401966 0.931 rs2185252 chr1:10415912 T/C cg19773385 chr1:10388646 KIF1B -0.39 -6.67 -0.34 1.01e-10 Hepatocellular carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02132458 chr4:57333267 SRP72 0.5 6.61 0.34 1.5e-10 Pancreatic cancer; LIHC cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg27535305 chr1:53392650 SCP2 0.32 6.26 0.32 1.14e-9 Monocyte count; LIHC cis rs7618501 1.000 rs6785549 chr3:49736565 G/A cg21467203 chr3:49911342 NA 0.4 6.88 0.35 2.83e-11 Intelligence (multi-trait analysis); LIHC cis rs7584330 0.554 rs10176035 chr2:238433449 T/C cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.39e-9 Prostate cancer; LIHC cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11671005 0.572 rs11669127 chr19:59003830 A/G cg25952890 chr19:58913133 NA -0.65 -6.45 -0.33 3.91e-10 Mean platelet volume; LIHC cis rs12594515 0.967 rs8039088 chr15:45990178 T/C cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC trans rs1814175 0.571 rs12294066 chr11:49738287 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.59 -0.74 7.56e-62 Height; LIHC cis rs77861329 1.000 rs9841469 chr3:52166596 C/A cg08692210 chr3:52188851 WDR51A 0.83 7.85 0.39 5.47e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs7902334 1.000 rs7902334 chr10:12645941 A/C cg09958065 chr10:12648526 CAMK1D -0.64 -7.46 -0.37 7.07e-13 Coronary artery aneurysm in Kawasaki disease; LIHC cis rs2797685 1.000 rs1689904 chr1:7890801 C/T cg04725166 chr1:7887271 PER3 -0.41 -7.3 -0.37 2e-12 Crohn's disease; LIHC cis rs7131987 0.903 rs2216853 chr12:29413248 C/G cg21486233 chr12:29375141 FAR2 0.31 6.25 0.32 1.22e-9 QT interval; LIHC cis rs9534288 0.797 rs7982998 chr13:46601535 C/T cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg17971929 chr21:40555470 PSMG1 0.85 10.53 0.49 1.2e-22 Cognitive function; LIHC trans rs2359714 0.935 rs7526525 chr1:118807059 T/C cg19861078 chr7:7936962 NA -0.31 -6.16 -0.32 2.05e-9 Breast size; LIHC cis rs9457247 0.663 rs9457257 chr6:167440736 G/A cg12798992 chr6:167411361 FGFR1OP 0.46 7.19 0.36 4.2e-12 Crohn's disease; LIHC cis rs67981189 0.593 rs8005160 chr14:71446494 G/T cg15816911 chr14:71606274 NA 0.4 6.53 0.33 2.34e-10 Schizophrenia; LIHC cis rs2072438 0.503 rs4837810 chr9:123881199 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 6.4 0.33 5.23e-10 Rheumatoid arthritis; LIHC cis rs2576037 0.526 rs2576051 chr18:44557884 G/A cg19077165 chr18:44547161 KATNAL2 0.44 6.6 0.34 1.59e-10 Personality dimensions; LIHC cis rs6089584 0.854 rs8117075 chr20:60613766 T/C cg06108461 chr20:60628389 TAF4 -1.01 -17.29 -0.68 1.4e-48 Body mass index; LIHC cis rs68170813 0.605 rs75659533 chr7:107134987 A/G cg02696742 chr7:106810147 HBP1 -0.55 -6.19 -0.32 1.7e-9 Coronary artery disease; LIHC cis rs3806843 0.966 rs12659129 chr5:140147248 T/C cg19875535 chr5:140030758 IK 0.37 5.98 0.31 5.72e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10791097 0.694 rs4456262 chr11:130755813 C/T cg12179176 chr11:130786555 SNX19 -0.86 -13.19 -0.58 2.1e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs4906332 1.000 rs2065015 chr14:103904061 G/T cg11091909 chr13:33640726 NA -0.33 -6.06 -0.31 3.61e-9 Coronary artery disease; LIHC cis rs6598955 0.543 rs3795687 chr1:26560745 G/A cg04990556 chr1:26633338 UBXN11 0.75 11.22 0.52 4.42e-25 Obesity-related traits; LIHC trans rs11098499 0.863 rs59732491 chr4:120489588 G/C cg25214090 chr10:38739885 LOC399744 0.58 9.49 0.46 3.93e-19 Corneal astigmatism; LIHC cis rs10089 1.000 rs13356473 chr5:127478250 T/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.77 0.34 5.6e-11 Ileal carcinoids; LIHC cis rs3008870 1.000 rs12044278 chr1:67460977 T/C cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs11955398 0.625 rs11745077 chr5:59955716 C/T cg02684056 chr5:59996105 DEPDC1B 0.42 5.92 0.3 7.97e-9 Intelligence (multi-trait analysis); LIHC cis rs3768617 0.510 rs2296300 chr1:183099701 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs4689592 0.503 rs10516184 chr4:7060959 C/T cg26116260 chr4:7069785 GRPEL1 1.02 17.85 0.69 7.7e-51 Monocyte percentage of white cells; LIHC cis rs7095607 0.606 rs7913133 chr10:69961470 A/G cg18986048 chr10:69913749 MYPN 0.39 5.92 0.31 7.67e-9 Lung function (FVC); LIHC cis rs12711979 0.509 rs10187740 chr2:3823965 A/G cg17052675 chr2:3827356 NA 0.69 15.31 0.64 1.13e-40 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06825153 chr1:90287453 LRRC8D -0.45 -6.36 -0.33 6.44e-10 Pancreatic cancer; LIHC cis rs2439831 0.867 rs2245176 chr15:43750762 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.57 0.59 7.69e-34 Lung cancer in ever smokers; LIHC cis rs903552 0.932 rs1587108 chr15:102006825 G/A cg19295451 chr15:102010161 PCSK6 -0.48 -6.64 -0.34 1.26e-10 Diabetic kidney disease; LIHC cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg22907277 chr7:1156413 C7orf50 0.43 6.17 0.32 1.95e-9 Longevity;Endometriosis; LIHC cis rs12586317 0.620 rs28870452 chr14:35536878 C/A cg05294307 chr14:35346193 BAZ1A -0.46 -6.74 -0.34 6.65e-11 Psoriasis; LIHC cis rs7635838 0.619 rs346087 chr3:11274354 A/G cg00170343 chr3:11313890 ATG7 0.51 8.04 0.4 1.51e-14 HDL cholesterol; LIHC cis rs4665809 1.000 rs6749855 chr2:26255263 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.66 -7.84 -0.39 5.95e-14 Gut microbiome composition (summer); LIHC cis rs7020830 0.867 rs563132 chr9:37245476 A/T cg14294708 chr9:37120828 ZCCHC7 1.03 21.04 0.75 1.16e-63 Schizophrenia; LIHC cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.4e-30 Menopause (age at onset); LIHC cis rs3768617 0.510 rs6424885 chr1:183066254 T/G ch.1.3577855R chr1:183094577 LAMC1 0.63 10.92 0.51 5.31e-24 Fuchs's corneal dystrophy; LIHC cis rs7833986 0.501 rs72653921 chr8:56897157 T/C cg23139584 chr8:56987506 RPS20;SNORD54 0.87 8.76 0.43 9.08e-17 Height; LIHC trans rs2797160 1.000 rs2747720 chr6:126009458 A/G cg05039488 chr6:79577232 IRAK1BP1 0.46 6.5 0.33 2.88e-10 Endometrial cancer; LIHC cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23640757 chr6:7889014 TXNDC5 -0.45 -7.15 -0.36 5.41e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs7131987 0.903 rs7308125 chr12:29425211 T/C cg16970926 chr12:29381810 FAR2 0.27 5.72 0.3 2.33e-8 QT interval; LIHC cis rs4919694 1.000 rs80327774 chr10:104656671 T/C cg04362960 chr10:104952993 NT5C2 1.13 8.79 0.43 7.28e-17 Arsenic metabolism; LIHC trans rs61931739 0.534 rs4931770 chr12:34044479 G/T cg26384229 chr12:38710491 ALG10B 0.49 6.82 0.35 4.04e-11 Morning vs. evening chronotype; LIHC cis rs778371 0.723 rs1022329 chr2:233591239 T/C cg08000102 chr2:233561755 GIGYF2 0.88 14.75 0.62 1.82e-38 Schizophrenia; LIHC cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg03264133 chr6:25882463 NA -1.09 -17.39 -0.69 5.58e-49 Urate levels; LIHC trans rs9660180 0.837 rs915292 chr1:1792157 A/C cg21139485 chr7:99987584 PILRA -0.27 -6.06 -0.31 3.5e-9 Body mass index; LIHC cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg11301795 chr4:187892539 NA -0.27 -7.11 -0.36 6.9e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs8005677 1.000 rs4981446 chr14:23381413 A/G cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs709400 0.663 rs72710714 chr14:103981849 T/G cg26031613 chr14:104095156 KLC1 0.79 9.69 0.46 9.14e-20 Body mass index; LIHC cis rs7312774 0.748 rs12308071 chr12:107314539 T/A cg16260113 chr12:107380972 MTERFD3 0.75 9.82 0.47 3.15e-20 Severe influenza A (H1N1) infection; LIHC cis rs2731664 0.792 rs2630767 chr5:176870700 T/C cg23176889 chr5:176863531 GRK6 -0.71 -12.66 -0.56 2.19e-30 Intelligence (multi-trait analysis); LIHC cis rs7020830 0.931 rs6476613 chr9:37084340 A/G cg14294708 chr9:37120828 ZCCHC7 1.01 20.59 0.74 7.45e-62 Schizophrenia; LIHC cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs523522 0.962 rs687873 chr12:121019634 G/A cg12219531 chr12:120966889 COQ5 0.68 13.23 0.58 1.46e-32 High light scatter reticulocyte count; LIHC cis rs1256061 0.603 rs1256037 chr14:64743301 G/A cg23250157 chr14:64679961 SYNE2 0.4 5.92 0.3 8.02e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs4718428 0.672 rs12530806 chr7:66390724 A/G cg12165864 chr7:66369176 NA -0.46 -6.77 -0.34 5.63e-11 Corneal structure; LIHC cis rs17345786 0.906 rs72944107 chr3:101197190 C/T cg12386194 chr3:101231763 SENP7 0.6 7.84 0.39 5.8e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs10733682 0.659 rs3861879 chr9:129464856 A/G cg00232160 chr9:129468157 NA 0.35 6.28 0.32 1.06e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs904251 0.861 rs1757183 chr6:37484790 C/T cg01843034 chr6:37503916 NA 0.42 6.67 0.34 1.02e-10 Cognitive performance; LIHC trans rs1728785 1.000 rs1645981 chr16:68571648 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.82e-9 Ulcerative colitis; LIHC cis rs12291225 0.753 rs1431374 chr11:14303975 T/C cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.11e-31 Sense of smell; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23808061 chr1:179923593 CEP350 0.45 6.44 0.33 4e-10 Pancreatic cancer; LIHC cis rs6782228 0.565 rs67445542 chr3:128330526 T/C cg16766828 chr3:128327626 NA -0.41 -6.49 -0.33 3.05e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs4665809 0.590 rs7606351 chr2:26292545 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.36 -0.45 1.06e-18 Gut microbiome composition (summer); LIHC cis rs709400 0.633 rs1951391 chr14:103898313 T/C cg26031613 chr14:104095156 KLC1 0.75 10.01 0.48 7.28e-21 Body mass index; LIHC trans rs13202860 1.000 rs35782874 chr6:87186506 G/A cg27326224 chr7:950474 ADAP1 -0.57 -6.32 -0.32 8.05e-10 Sexual dysfunction (female); LIHC cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.29 0.45 1.85e-18 Platelet count; LIHC cis rs1865721 0.728 rs7232269 chr18:73219023 G/A cg26385618 chr18:73139727 C18orf62 -0.27 -6.98 -0.35 1.54e-11 Intelligence; LIHC cis rs4595586 0.525 rs17467376 chr12:39377551 T/G cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs8062405 0.723 rs4788079 chr16:28559363 C/A cg16576597 chr16:28551801 NUPR1 0.5 7.92 0.39 3.44e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs877282 0.735 rs111609055 chr10:826539 A/G cg22713356 chr15:30763199 NA 0.82 7.21 0.36 3.57e-12 Uric acid levels; LIHC trans rs7618501 0.521 rs7615206 chr3:49937505 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.46 6.88 0.35 2.86e-11 Intelligence (multi-trait analysis); LIHC cis rs9325144 0.600 rs12424410 chr12:38758035 A/T cg26384229 chr12:38710491 ALG10B -0.55 -7.51 -0.38 5.16e-13 Morning vs. evening chronotype; LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg06951627 chr6:26196580 NA 0.55 6.43 0.33 4.39e-10 Gout;Renal underexcretion gout; LIHC cis rs1878931 0.624 rs27241 chr16:3447282 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.34 -0.41 1.79e-15 Body mass index (adult); LIHC trans rs2243480 1.000 rs2243480 chr7:65599196 C/T cg10756647 chr7:56101905 PSPH 1.02 11.74 0.54 5.57e-27 Diabetic kidney disease; LIHC cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg21724239 chr8:58056113 NA 0.64 7.89 0.39 4.03e-14 Developmental language disorder (linguistic errors); LIHC cis rs918629 0.798 rs7724599 chr5:95323378 T/C cg10483112 chr5:95245456 ELL2 -0.36 -6.29 -0.32 9.51e-10 IgG glycosylation; LIHC cis rs55665837 0.559 rs11023209 chr11:14422600 T/C cg19336497 chr11:14380999 RRAS2 -0.58 -10.77 -0.5 1.8e-23 Vitamin D levels; LIHC cis rs7582180 0.606 rs11684004 chr2:100954783 C/T cg14675211 chr2:100938903 LONRF2 0.53 8.35 0.41 1.66e-15 Intelligence (multi-trait analysis); LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg10570662 chr22:19159548 NA -0.44 -6.15 -0.32 2.15e-9 Triglycerides; LIHC cis rs9929218 0.953 rs2902323 chr16:68736292 C/T cg01231543 chr16:68741748 NA 0.39 5.77 0.3 1.76e-8 Colorectal cancer; LIHC cis rs7552404 0.921 rs10873685 chr1:76218818 A/C cg22875332 chr1:76189707 ACADM 0.48 6.98 0.35 1.59e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs3806843 0.766 rs801176 chr5:140087010 A/G cg19875535 chr5:140030758 IK 0.39 6.57 0.33 1.83e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs9296092 0.560 rs9469500 chr6:33526196 C/T cg13560919 chr6:33536144 NA -0.39 -6.41 -0.33 4.74e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs60871478 0.730 rs13222476 chr7:826630 T/C cg05535760 chr7:792225 HEATR2 0.97 13.54 0.59 9.77e-34 Cerebrospinal P-tau181p levels; LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg10411590 chr13:21900810 NA 0.45 7.49 0.38 5.9e-13 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs3849570 0.696 rs13092157 chr3:81875332 T/A cg07356753 chr3:81810745 GBE1 -0.56 -8.8 -0.43 6.69e-17 Waist circumference;Body mass index; LIHC cis rs7618501 0.635 rs7635002 chr3:49989155 T/G cg21467203 chr3:49911342 NA -0.45 -7.81 -0.39 6.94e-14 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg23978390 chr7:1156363 C7orf50 0.62 9.57 0.46 2.17e-19 Longevity;Endometriosis; LIHC cis rs7917772 0.510 rs2001389 chr10:104375258 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.03e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7903847 0.642 rs12258560 chr10:99137048 T/C cg08345082 chr10:99160200 RRP12 -0.37 -6.11 -0.31 2.67e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6089584 1.000 rs3787424 chr20:60559219 G/A cg12751644 chr20:60527061 NA -0.36 -5.99 -0.31 5.41e-9 Body mass index; LIHC cis rs11122272 0.735 rs2009873 chr1:231499236 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.46 0.46 5.03e-19 Hemoglobin concentration; LIHC cis rs344364 0.511 rs1742468 chr16:1950243 C/G cg26897989 chr16:1907736 C16orf73 -0.5 -6.18 -0.32 1.84e-9 Glomerular filtration rate in chronic kidney disease; LIHC trans rs1814175 0.645 rs28454367 chr11:50045708 G/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC trans rs3780486 0.846 rs7865745 chr9:33140976 A/G cg20290983 chr6:43655470 MRPS18A -1.17 -30.11 -0.85 3.42e-98 IgG glycosylation; LIHC cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.51 0.56 7.82e-30 Total body bone mineral density; LIHC cis rs3981351 0.797 rs61866462 chr10:115464690 C/T cg24846397 chr10:115438155 CASP7 -0.46 -7.13 -0.36 5.84e-12 Obesity-related traits; LIHC cis rs1577917 0.655 rs7766485 chr6:86263555 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.37 6.57 0.33 1.89e-10 Response to antipsychotic treatment; LIHC trans rs11098499 0.909 rs35111518 chr4:120440682 A/G cg25214090 chr10:38739885 LOC399744 0.62 9.98 0.47 9.69e-21 Corneal astigmatism; LIHC cis rs7296418 0.630 rs11057238 chr12:123767971 C/A cg05973401 chr12:123451056 ABCB9 0.41 6.3 0.32 9.22e-10 Platelet count; LIHC trans rs875971 0.638 rs6460305 chr7:66060408 G/A cg26939375 chr7:64535504 NA -0.43 -6.93 -0.35 2.05e-11 Aortic root size; LIHC cis rs910316 0.692 rs7156586 chr14:75506230 A/T cg08847533 chr14:75593920 NEK9 0.57 10.15 0.48 2.44e-21 Height; LIHC cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25046584 chr21:32932016 TIAM1 0.33 6.04 0.31 4.02e-9 Cognitive function; LIHC cis rs7520050 0.778 rs3014216 chr1:46035760 A/T cg03146154 chr1:46216737 IPP 0.46 7.39 0.37 1.11e-12 Red blood cell count;Reticulocyte count; LIHC cis rs9399135 0.636 rs4646871 chr6:135265617 A/G cg24558204 chr6:135376177 HBS1L -0.41 -6.73 -0.34 7.09e-11 Red blood cell count; LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg00091569 chr3:40428383 ENTPD3 0.4 6.83 0.35 4.01e-11 Renal cell carcinoma; LIHC cis rs2422052 0.639 rs11676728 chr2:118654927 T/C cg22545206 chr2:118617499 NA 0.38 6.27 0.32 1.07e-9 Mosquito bite size; LIHC cis rs6942756 0.806 rs68184415 chr7:128988862 C/T cg02491457 chr7:128862824 NA -0.56 -8.39 -0.41 1.31e-15 White matter hyperintensity burden; LIHC cis rs6442522 0.780 rs13095978 chr3:15441110 G/T cg16303742 chr3:15540471 COLQ 0.38 5.99 0.31 5.28e-9 Uric acid levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04145193 chr17:38083691 ORMDL3 0.48 6.62 0.34 1.4e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.58 -8.94 -0.44 2.4e-17 Height; LIHC trans rs4843747 0.671 rs13334603 chr16:88116016 T/C cg09572067 chr16:29127029 RRN3P2 0.51 8.14 0.4 7.53e-15 Menopause (age at onset); LIHC cis rs2204008 0.745 rs12146863 chr12:38502346 G/A cg26384229 chr12:38710491 ALG10B 0.69 9.64 0.46 1.34e-19 Bladder cancer; LIHC cis rs796364 0.806 rs115717210 chr2:201006247 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs7633770 0.664 rs7373994 chr3:46701114 C/G cg11219411 chr3:46661640 NA -0.39 -6.7 -0.34 8.42e-11 Coronary artery disease; LIHC cis rs804280 0.662 rs11250164 chr8:11610686 C/T cg12568669 chr8:11666485 FDFT1 0.29 5.89 0.3 9.19e-9 Myopia (pathological); LIHC cis rs10751667 0.643 rs7396046 chr11:937176 T/C cg06064525 chr11:970664 AP2A2 -0.55 -14.97 -0.63 2.48e-39 Alzheimer's disease (late onset); LIHC cis rs9733 0.519 rs7511673 chr1:150707636 A/T cg13175981 chr1:150552382 MCL1 -0.42 -5.74 -0.3 2.12e-8 Tonsillectomy; LIHC cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs367615 0.552 rs2115511 chr5:108725403 A/T cg17395555 chr5:108820864 NA -0.28 -5.97 -0.31 6.04e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs4665809 0.877 rs35224700 chr2:26298037 T/C cg27170947 chr2:26402098 FAM59B 0.58 6.27 0.32 1.07e-9 Gut microbiome composition (summer); LIHC trans rs875971 0.545 rs67397473 chr7:65633305 A/G cg26939375 chr7:64535504 NA 0.4 6.42 0.33 4.54e-10 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04197313 chr15:67547198 IQCH;AAGAB -0.51 -6.97 -0.35 1.64e-11 Pancreatic cancer; LIHC cis rs950169 0.881 rs62029596 chr15:84955434 A/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.5 0.42 5.84e-16 Schizophrenia; LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.42 -5.94 -0.31 7.07e-9 Longevity; LIHC cis rs62244186 0.608 rs2888390 chr3:44511405 G/A cg25364880 chr3:44379878 C3orf23 0.59 8.22 0.41 4.39e-15 Depressive symptoms; LIHC cis rs6960043 0.584 rs2189724 chr7:15041822 G/A cg19272540 chr7:15055459 NA 0.25 6.68 0.34 9.83e-11 Type 2 diabetes; LIHC cis rs694739 0.930 rs574087 chr11:64102948 A/G cg02228329 chr11:64053129 BAD;GPR137 0.75 10.72 0.5 2.6e-23 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg24693881 chr1:107596107 NA 0.53 9.31 0.45 1.54e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1419980 0.630 rs2377089 chr12:7737325 T/C cg25828445 chr12:7781288 NA 0.43 6.64 0.34 1.26e-10 HDL cholesterol levels; LIHC cis rs10870270 1.000 rs6560695 chr10:133774986 C/A cg26149184 chr10:133730230 NA 0.47 7.48 0.37 6.46e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg18404041 chr3:52824283 ITIH1 -0.58 -9.73 -0.47 6.39e-20 Electroencephalogram traits; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg08219700 chr8:58056026 NA 0.52 7.15 0.36 5.24e-12 Developmental language disorder (linguistic errors); LIHC trans rs1499614 1.000 rs34250985 chr7:66161062 A/T cg07424592 chr7:64974309 NA 0.72 7.46 0.37 7.2e-13 Gout; LIHC cis rs10861342 0.892 rs7966106 chr12:105615272 C/G cg23923672 chr12:105501055 KIAA1033 -0.64 -7.16 -0.36 5.1e-12 IgG glycosylation; LIHC cis rs12477438 0.798 rs13412764 chr2:99583733 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.87 -0.47 2.27e-20 Chronic sinus infection; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13099829 chr1:2237991 SKI 0.43 6.22 0.32 1.47e-9 Longevity; LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg00656387 chr3:40428638 ENTPD3 0.48 7.94 0.39 2.89e-14 Renal cell carcinoma; LIHC cis rs1799949 0.965 rs8176310 chr17:41199913 T/C cg05368731 chr17:41323189 NBR1 0.69 11.44 0.53 6.89e-26 Menopause (age at onset); LIHC trans rs2243480 0.706 rs34466769 chr7:65453292 A/C cg10756647 chr7:56101905 PSPH 1.12 16.83 0.67 9.77e-47 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26706201 chr11:57103334 SSRP1 0.48 6.19 0.32 1.68e-9 Lung function (FEV1/FVC); LIHC cis rs9399137 0.507 rs7768278 chr6:135274957 T/C cg24558204 chr6:135376177 HBS1L 0.6 10.17 0.48 2.06e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs4409675 0.576 rs6565 chr1:28213157 T/C cg23691781 chr1:28212827 C1orf38 0.31 7.38 0.37 1.2e-12 Corneal astigmatism; LIHC cis rs709400 0.930 rs10149249 chr14:104047757 C/T cg26031613 chr14:104095156 KLC1 1.03 13.79 0.6 1.01e-34 Body mass index; LIHC cis rs9517320 0.534 rs4771306 chr13:99143661 T/C cg20487152 chr13:99095054 FARP1 -0.39 -6.6 -0.34 1.54e-10 Longevity; LIHC cis rs67478160 0.619 rs11623546 chr14:104269098 A/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.86 0.57 3.97e-31 Schizophrenia; LIHC cis rs1577917 0.874 rs11756621 chr6:86740063 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.17 -0.36 4.75e-12 Response to antipsychotic treatment; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 11.96 0.54 8.84e-28 Prudent dietary pattern; LIHC cis rs7264396 0.561 rs2050930 chr20:34579397 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -8.44 -0.42 9.07e-16 Total cholesterol levels; LIHC cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.89 0.3 9.32e-9 Menopause (age at onset); LIHC cis rs4319547 0.915 rs10734924 chr12:123018894 T/G cg05707623 chr12:122985044 ZCCHC8 -0.62 -8.34 -0.41 1.9e-15 Body mass index; LIHC cis rs798554 0.836 rs798502 chr7:2789880 G/T cg13628971 chr7:2884303 GNA12 -0.43 -6.49 -0.33 3.06e-10 Height; LIHC cis rs9871864 1.000 rs9871864 chr3:20352766 A/G cg00235661 chr3:20228976 SGOL1 -0.31 -5.94 -0.31 6.86e-9 Behavioural disinhibition (generation interaction); LIHC cis rs7044106 0.762 rs10818471 chr9:123394045 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.51 0.38 5.15e-13 Hip circumference adjusted for BMI; LIHC cis rs7249142 0.562 rs2239370 chr19:19292674 T/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.42 -6.99 -0.35 1.43e-11 IgG glycosylation; LIHC cis rs35110281 0.666 rs9977076 chr21:45085829 G/A cg01579765 chr21:45077557 HSF2BP -0.33 -6.1 -0.31 2.81e-9 Mean corpuscular volume; LIHC cis rs2404602 0.735 rs12906143 chr15:76709523 T/A cg03037974 chr15:76606532 NA -0.64 -11.21 -0.52 4.74e-25 Blood metabolite levels; LIHC cis rs9291683 0.609 rs36084205 chr4:10028678 A/C cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.58e-13 Bone mineral density; LIHC cis rs7772486 0.840 rs2814867 chr6:146334030 C/A cg13319975 chr6:146136371 FBXO30 -0.37 -6.12 -0.31 2.51e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg05267444 chr8:11627012 NEIL2 -0.48 -5.94 -0.31 6.89e-9 Monocyte count; LIHC cis rs3015497 0.586 rs12587821 chr14:51092554 A/G cg09863266 chr14:51125203 SAV1 -0.39 -6.17 -0.32 1.88e-9 Mean platelet volume; LIHC cis rs4650994 0.509 rs7519794 chr1:178542390 G/T cg05350800 chr1:178550844 NA -0.35 -7.64 -0.38 2.26e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9640161 0.659 rs11975886 chr7:150010362 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -7.99 -0.4 2.14e-14 Blood protein levels;Circulating chemerin levels; LIHC trans rs208520 0.739 rs1935894 chr6:66891434 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.33 -0.41 1.97e-15 Exhaled nitric oxide output; LIHC cis rs9733 0.687 rs12410050 chr1:150857141 A/G cg18016565 chr1:150552671 MCL1 -0.52 -9.64 -0.46 1.31e-19 Tonsillectomy; LIHC cis rs6582630 0.502 rs4309219 chr12:38293584 A/G cg26384229 chr12:38710491 ALG10B 0.58 8.12 0.4 8.79e-15 Drug-induced liver injury (flucloxacillin); LIHC trans rs10028773 0.515 rs9994488 chr4:120587781 C/T cg25214090 chr10:38739885 LOC399744 0.44 7.02 0.35 1.17e-11 Educational attainment; LIHC cis rs116095464 0.558 rs9312957 chr5:202194 C/T cg22857025 chr5:266934 NA -1.64 -16.58 -0.67 1.01e-45 Breast cancer; LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg03188948 chr7:1209495 NA 0.49 6.99 0.35 1.41e-11 Longevity;Endometriosis; LIHC cis rs13394619 0.562 rs34532804 chr2:11746003 G/A cg07314298 chr2:11723111 GREB1 0.36 6.07 0.31 3.4e-9 Endometriosis; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.72 11.55 0.53 2.81e-26 Prudent dietary pattern; LIHC cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg15691649 chr6:25882328 NA -0.62 -8.35 -0.41 1.67e-15 Intelligence (multi-trait analysis); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg07148452 chr15:90176987 KIF7 0.42 6.07 0.31 3.47e-9 Immature fraction of reticulocytes; LIHC cis rs2354432 0.556 rs7516165 chr1:146866418 G/T cg25205988 chr1:146714368 CHD1L 0.78 8.5 0.42 5.88e-16 Mitochondrial DNA levels; LIHC cis rs3859192 0.599 rs34342173 chr17:38161507 T/C cg17467752 chr17:38218738 THRA -0.51 -8.64 -0.42 2.21e-16 White blood cell count; LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs736408 0.812 rs2270197 chr3:52824095 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.48 7.71 0.38 1.37e-13 Bipolar disorder; LIHC cis rs9915021 0.623 rs9890191 chr17:33964539 C/G cg20932281 chr17:33905541 PEX12 0.6 7.43 0.37 8.53e-13 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs752010 0.746 rs11210499 chr1:42089703 C/T cg06885757 chr1:42089581 HIVEP3 -0.31 -6.45 -0.33 3.72e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs8177253 1.000 rs8177240 chr3:133477701 T/G cg12373951 chr3:133503437 NA 0.69 12.12 0.55 2.28e-28 Iron status biomarkers; LIHC cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg03452623 chr4:187889614 NA 0.32 7.86 0.39 5e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs921968 0.541 rs636723 chr2:219373197 A/G cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs1419980 0.730 rs7137180 chr12:7745614 C/T cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09527731 chr5:132097228 SEPT8 0.42 6.2 0.32 1.66e-9 Pancreatic cancer; LIHC cis rs11645898 0.504 rs118034653 chr16:71922944 T/C cg03805757 chr16:71968109 PKD1L3 -0.82 -8.44 -0.42 8.93e-16 Blood protein levels; LIHC cis rs6952808 0.792 rs12536261 chr7:1953571 G/A cg14004847 chr7:1930337 MAD1L1 -0.47 -6.76 -0.34 5.84e-11 Bipolar disorder and schizophrenia; LIHC trans rs116095464 0.558 rs10067021 chr5:221490 C/T cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg02187348 chr16:89574699 SPG7 0.65 10.37 0.49 4.27e-22 Multiple myeloma (IgH translocation); LIHC cis rs7116495 0.609 rs7115513 chr11:71664495 T/A cg26138937 chr11:71823887 C11orf51 -1.28 -10.0 -0.48 8.22e-21 Severe influenza A (H1N1) infection; LIHC cis rs595982 0.527 rs12151238 chr19:49368613 T/C cg15549821 chr19:49342101 PLEKHA4 -0.64 -5.89 -0.3 9.08e-9 Red cell distribution width; LIHC trans rs526821 0.532 rs578067 chr11:55313690 T/G cg03929089 chr4:120376271 NA -0.45 -6.8 -0.35 4.63e-11 Pediatric bone mineral density (spine); LIHC cis rs600806 0.850 rs4970729 chr1:109979202 G/A cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.05 -0.31 3.83e-9 Intelligence (multi-trait analysis); LIHC cis rs208520 0.874 rs208469 chr6:66915891 T/C cg07460842 chr6:66804631 NA -0.69 -7.71 -0.38 1.37e-13 Exhaled nitric oxide output; LIHC cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg11764359 chr7:65958608 NA 0.58 6.12 0.31 2.54e-9 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg10755058 chr3:40428713 ENTPD3 0.41 6.89 0.35 2.77e-11 Renal cell carcinoma; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg16103275 chr6:290800 DUSP22 0.5 6.56 0.33 1.99e-10 Menopause (age at onset); LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.25 -0.32 1.25e-9 Total body bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20087917 chr14:77924039 C14orf133;AHSA1 0.44 7.56 0.38 3.8e-13 Cognitive function; LIHC cis rs965469 1.000 rs1040726 chr20:3264267 C/T cg25506879 chr20:3388711 C20orf194 -0.58 -6.98 -0.35 1.59e-11 IFN-related cytopenia; LIHC cis rs3749237 0.595 rs1464566 chr3:49459376 T/C cg07636037 chr3:49044803 WDR6 0.52 8.12 0.4 8.6e-15 Resting heart rate; LIHC cis rs12586317 0.514 rs61100068 chr14:35400232 A/T cg16230307 chr14:35515116 FAM177A1 0.77 12.0 0.54 6.54e-28 Psoriasis; LIHC cis rs2295359 0.824 rs12060309 chr1:67604219 T/C cg08029281 chr1:67600428 NA 0.38 6.42 0.33 4.44e-10 Psoriasis; LIHC cis rs10744422 0.800 rs2343110 chr12:123343571 T/G cg18912006 chr12:123335444 HIP1R -0.64 -7.67 -0.38 1.78e-13 Schizophrenia; LIHC cis rs3540 0.597 rs1978150 chr15:91037041 A/G cg22089800 chr15:90895588 ZNF774 -0.63 -8.65 -0.42 2.1e-16 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs739401 0.572 rs12276060 chr11:3015572 A/T cg20651018 chr11:3035856 CARS -0.35 -5.92 -0.31 7.68e-9 Longevity; LIHC cis rs477692 0.699 rs528549 chr10:131381574 A/G cg05714579 chr10:131428358 MGMT 0.43 7.07 0.36 8.58e-12 Response to temozolomide; LIHC cis rs1823913 1.000 rs7574570 chr2:192098516 G/A cg12404831 chr2:192114017 MYO1B -0.34 -6.71 -0.34 8.34e-11 Obesity-related traits; LIHC cis rs425535 0.619 rs9291189 chr4:74832037 A/C cg02530824 chr4:74847766 PF4 0.35 5.96 0.31 6.4e-9 Blood protein levels; LIHC cis rs477692 1.000 rs558764 chr10:131426957 G/T cg05714579 chr10:131428358 MGMT -0.46 -7.54 -0.38 4.19e-13 Response to temozolomide; LIHC cis rs965469 0.779 rs6037566 chr20:3331414 A/C cg25506879 chr20:3388711 C20orf194 -0.53 -6.54 -0.33 2.22e-10 IFN-related cytopenia; LIHC cis rs986417 0.606 rs7156375 chr14:61110627 G/A cg27398547 chr14:60952738 C14orf39 0.66 7.38 0.37 1.19e-12 Gut microbiota (bacterial taxa); LIHC cis rs6062302 0.522 rs3787107 chr20:62230576 G/A cg16989086 chr20:62203971 PRIC285 0.57 8.21 0.41 4.49e-15 Glioblastoma; LIHC cis rs965469 0.779 rs6051785 chr20:3339199 C/T cg25506879 chr20:3388711 C20orf194 -0.51 -6.27 -0.32 1.06e-9 IFN-related cytopenia; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg06873352 chr17:61820015 STRADA 0.75 13.7 0.6 2.43e-34 Prudent dietary pattern; LIHC cis rs9457247 0.846 rs2757052 chr6:167380174 T/C cg23791538 chr6:167370224 RNASET2 0.69 11.76 0.54 4.7e-27 Crohn's disease; LIHC cis rs1949733 1.000 rs6837429 chr4:8502374 A/G cg11789530 chr4:8429930 ACOX3 0.78 11.79 0.54 3.65e-27 Response to antineoplastic agents; LIHC cis rs597539 0.652 rs501799 chr11:68631240 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.73 10.73 0.5 2.43e-23 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2012796 0.743 rs8020575 chr14:81859521 G/A cg02996355 chr14:81879375 NA 0.71 11.63 0.53 1.45e-26 Night sleep phenotypes; LIHC cis rs240764 0.604 rs1336242 chr6:101199634 C/T cg09795085 chr6:101329169 ASCC3 0.41 5.92 0.31 7.65e-9 Neuroticism; LIHC trans rs4650994 1.000 rs4077194 chr1:178533832 A/C cg05059571 chr16:84539110 KIAA1609 0.36 6.26 0.32 1.14e-9 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2742417 0.609 rs11709306 chr3:45773732 G/A cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs4865169 0.934 rs3796531 chr4:57850846 A/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.63 -10.96 -0.51 3.71e-24 Breast cancer; LIHC cis rs79976124 0.837 rs12201218 chr6:66653619 C/T cg07460842 chr6:66804631 NA -0.63 -6.85 -0.35 3.46e-11 Type 2 diabetes; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg01162549 chr5:141367464 RNF14 0.38 6.05 0.31 3.73e-9 Immature fraction of reticulocytes; LIHC trans rs72766638 0.895 rs55924785 chr9:136929586 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.57 -6.32 -0.32 8.06e-10 Mosquito bite size; LIHC cis rs651907 0.535 rs34161138 chr3:101510388 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs6598955 0.670 rs6676619 chr1:26539035 T/G cg04990556 chr1:26633338 UBXN11 -0.56 -9.09 -0.44 8.38e-18 Obesity-related traits; LIHC cis rs875971 0.895 rs10755833 chr7:65913917 A/G cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg10802521 chr3:52805072 NEK4 0.45 7.66 0.38 1.95e-13 Electroencephalogram traits; LIHC cis rs2637266 0.756 rs2583063 chr10:78558048 T/C cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.96e-9 Pulmonary function; LIHC cis rs240764 0.782 rs7748644 chr6:101166809 T/G cg12253828 chr6:101329408 ASCC3 -0.41 -6.35 -0.32 6.89e-10 Neuroticism; LIHC cis rs6424115 1.000 rs7521961 chr1:24157634 C/T cg10978503 chr1:24200527 CNR2 -0.38 -9.0 -0.44 1.64e-17 Immature fraction of reticulocytes; LIHC cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg24209194 chr3:40518798 ZNF619 0.46 6.55 0.33 2.15e-10 Renal cell carcinoma; LIHC cis rs17376456 0.569 rs68122392 chr5:93077807 A/T cg25358565 chr5:93447407 FAM172A 0.8 7.68 0.38 1.63e-13 Diabetic retinopathy; LIHC cis rs8108269 1.000 rs10404142 chr19:46160698 C/A cg13320842 chr19:46175254 GIPR 0.43 8.05 0.4 1.37e-14 Type 2 diabetes; LIHC cis rs16912059 0.661 rs12293486 chr11:24296391 T/G ch.11.24196551F chr11:24239977 NA 0.8 7.64 0.38 2.21e-13 Thrombin-antithrombin complex levels in ischemic stroke; LIHC cis rs17826219 0.706 rs9893922 chr17:29068425 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.33 0.41 1.98e-15 Body mass index; LIHC cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg14393609 chr7:65229607 NA 0.44 6.56 0.33 2.04e-10 Calcium levels; LIHC cis rs10792665 0.671 rs4076574 chr11:82667726 C/T cg24227371 chr11:82718527 RAB30 -0.3 -6.61 -0.34 1.49e-10 Obesity-related traits; LIHC cis rs3806843 0.676 rs778594 chr5:140027304 T/C cg19875535 chr5:140030758 IK -0.43 -7.05 -0.36 9.96e-12 Depressive symptoms (multi-trait analysis); LIHC cis rs4892230 1 rs4892230 chr18:72155572 G/A cg25817165 chr18:72167213 CNDP2 -0.5 -8.09 -0.4 1.05e-14 Mononucleosis; LIHC cis rs1670533 1.000 rs13135215 chr4:1054364 A/G cg27284194 chr4:1044797 NA 0.6 8.93 0.43 2.6e-17 Recombination rate (females); LIHC cis rs367615 0.704 rs6889301 chr5:108835181 C/T cg17395555 chr5:108820864 NA 0.4 8.52 0.42 5.14e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs796364 1.000 rs166845 chr2:200823360 T/A cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.52e-9 Schizophrenia; LIHC cis rs7762018 0.607 rs3800544 chr6:170058374 C/T cg19338460 chr6:170058176 WDR27 -0.79 -9.86 -0.47 2.32e-20 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7659604 0.689 rs59131059 chr4:122666357 C/T cg19748678 chr4:122722346 EXOSC9 0.35 5.77 0.3 1.81e-8 Type 2 diabetes; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg20762182 chr15:69727293 KIF23 0.42 6.44 0.33 4.09e-10 Immature fraction of reticulocytes; LIHC cis rs11098699 0.750 rs1500122 chr4:124220060 A/C cg09941581 chr4:124220074 SPATA5 0.33 6.57 0.33 1.92e-10 Mosquito bite size; LIHC cis rs1018836 0.923 rs7840846 chr8:91565501 T/A cg16814680 chr8:91681699 NA -0.61 -9.75 -0.47 5.44e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1577917 0.958 rs1838958 chr6:86563968 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.07 -0.4 1.22e-14 Response to antipsychotic treatment; LIHC cis rs1707322 1.000 rs10890381 chr1:46451771 T/G cg03146154 chr1:46216737 IPP 0.47 7.54 0.38 4.19e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9790314 1.000 rs4350933 chr3:160955879 G/T cg04691961 chr3:161091175 C3orf57 -0.33 -5.71 -0.3 2.41e-8 Morning vs. evening chronotype; LIHC cis rs4925386 0.921 rs11204472 chr20:60920887 G/A cg24112000 chr20:60950667 NA 0.45 7.14 0.36 5.48e-12 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg25894440 chr7:65020034 NA 0.53 6.07 0.31 3.34e-9 Diabetic kidney disease; LIHC cis rs9611565 0.559 rs5751160 chr22:42175695 A/G cg03806693 chr22:41940476 POLR3H 0.96 10.0 0.48 8.24e-21 Vitiligo; LIHC cis rs2239547 0.657 rs12496077 chr3:52886241 G/A cg18404041 chr3:52824283 ITIH1 -0.42 -5.88 -0.3 9.58e-9 Schizophrenia; LIHC cis rs1385374 0.858 rs959989 chr12:129292708 A/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.68 0.38 1.73e-13 Systemic lupus erythematosus; LIHC cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg05368731 chr17:41323189 NBR1 0.71 12.15 0.55 1.72e-28 Menopause (age at onset); LIHC cis rs597539 0.617 rs672853 chr11:68636362 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.41 0.49 3.08e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg16434002 chr17:42200994 HDAC5 -0.54 -7.88 -0.39 4.3e-14 Total body bone mineral density; LIHC cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg18230493 chr5:56204884 C5orf35 -0.44 -6.13 -0.31 2.46e-9 Initial pursuit acceleration; LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg23782820 chr8:58130467 NA 0.33 5.86 0.3 1.1e-8 Developmental language disorder (linguistic errors); LIHC cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg15691649 chr6:25882328 NA -0.63 -8.64 -0.42 2.24e-16 Intelligence (multi-trait analysis); LIHC cis rs796364 0.951 rs3098341 chr2:200792498 G/T cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.61e-9 Schizophrenia; LIHC cis rs4934494 0.768 rs12571918 chr10:91434677 G/T cg19698084 chr10:91461284 KIF20B -0.49 -6.49 -0.33 2.93e-10 Red blood cell count; LIHC trans rs11039798 0.512 rs1988465 chr11:49011303 C/T cg15704280 chr7:45808275 SEPT13 0.59 6.59 0.34 1.64e-10 Axial length; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27390425 chr1:212964975 TATDN3;NSL1 -0.44 -6.39 -0.33 5.54e-10 Pancreatic cancer; LIHC cis rs9911578 1.000 rs304292 chr17:56824123 G/A cg12560992 chr17:57184187 TRIM37 0.96 17.17 0.68 4.27e-48 Intelligence (multi-trait analysis); LIHC trans rs2235573 0.527 rs139886 chr22:38371328 C/T cg19894588 chr14:64061835 NA 0.5 6.65 0.34 1.18e-10 Glioblastoma;Glioma; LIHC cis rs7666738 0.830 rs7664051 chr4:98766970 C/G cg05340658 chr4:99064831 C4orf37 0.64 11.56 0.53 2.49e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6545883 0.895 rs2442029 chr2:61679552 G/T cg14146966 chr2:61757674 XPO1 0.46 7.94 0.39 2.91e-14 Tuberculosis; LIHC cis rs1707322 0.964 rs7546237 chr1:46285610 A/C cg06784218 chr1:46089804 CCDC17 0.35 6.38 0.33 5.9e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7617480 0.558 rs12715430 chr3:48942855 A/C cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.43 0.33 4.27e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs12478296 0.892 rs60545379 chr2:243034390 A/T cg18898632 chr2:242989856 NA -0.56 -7.53 -0.38 4.44e-13 Obesity-related traits; LIHC cis rs9814567 1.000 rs13081688 chr3:134259954 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10751667 1.000 rs10794349 chr11:945678 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.37 0.52 1.29e-25 Alzheimer's disease (late onset); LIHC cis rs508618 0.697 rs7534248 chr1:231554531 C/T cg06096015 chr1:231504339 EGLN1 -0.45 -7.43 -0.37 8.5e-13 Red blood cell count; LIHC cis rs116095464 0.558 rs6874745 chr5:264527 A/G cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs1008375 0.800 rs28754811 chr4:17612312 C/T cg02297831 chr4:17616191 MED28 0.47 7.27 0.37 2.45e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6424115 0.830 rs2503002 chr1:24196957 C/G cg04160030 chr1:24195659 FUCA1 -0.37 -6.14 -0.32 2.31e-9 Immature fraction of reticulocytes; LIHC cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.11 0.52 1.04e-24 Platelet count; LIHC cis rs425277 1.000 rs262667 chr1:2082722 T/C cg24578937 chr1:2090814 PRKCZ 0.5 9.04 0.44 1.17e-17 Height; LIHC cis rs7845219 0.525 rs7820818 chr8:95919231 G/A cg13393036 chr8:95962371 TP53INP1 -0.32 -5.97 -0.31 5.91e-9 Type 2 diabetes; LIHC cis rs12744310 0.887 rs34152153 chr1:41801408 T/C cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6442522 0.933 rs6442518 chr3:15422050 C/G cg16303742 chr3:15540471 COLQ 0.35 5.82 0.3 1.38e-8 Uric acid levels; LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg05185784 chr16:90016020 DEF8 -0.48 -6.33 -0.32 7.84e-10 Skin colour saturation; LIHC cis rs8177253 0.901 rs9843728 chr3:133501407 C/T cg12373951 chr3:133503437 NA 0.67 11.87 0.54 1.84e-27 Iron status biomarkers; LIHC cis rs10870270 1.000 rs10430617 chr10:133748889 T/C cg26149184 chr10:133730230 NA 0.46 7.21 0.36 3.71e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs11098499 1.000 rs11098499 chr4:120187611 C/T cg09307838 chr4:120376055 NA 0.72 10.77 0.5 1.79e-23 Corneal astigmatism; LIHC cis rs2354432 0.607 rs1530335 chr1:146685288 T/C cg25205988 chr1:146714368 CHD1L 0.98 6.47 0.33 3.34e-10 Mitochondrial DNA levels; LIHC cis rs9733 0.519 rs11587444 chr1:150722844 A/G cg15448220 chr1:150897856 SETDB1 0.42 6.48 0.33 3.17e-10 Tonsillectomy; LIHC cis rs3741798 0.908 rs61922046 chr12:12495675 A/T cg08615371 chr12:12503544 MANSC1 0.9 7.28 0.37 2.29e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs4665809 0.652 rs6728090 chr2:26524726 C/T cg04944784 chr2:26401820 FAM59B -0.59 -8.04 -0.4 1.49e-14 Gut microbiome composition (summer); LIHC cis rs898097 1.000 rs898098 chr17:80904564 G/A cg15664640 chr17:80829946 TBCD 0.64 10.6 0.5 7.06e-23 Breast cancer; LIHC cis rs10911251 0.528 rs2182020 chr1:183074964 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.93 0.51 4.56e-24 Colorectal cancer; LIHC cis rs12477438 0.834 rs1563108 chr2:99701153 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.55 -8.75 -0.43 9.75e-17 Chronic sinus infection; LIHC cis rs926392 0.533 rs6129162 chr20:37683195 G/A cg16355469 chr20:37678765 NA 0.54 8.61 0.42 2.68e-16 Dialysis-related mortality; LIHC cis rs2204008 0.837 rs12370891 chr12:37984531 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg16606324 chr3:10149918 C3orf24 0.52 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs28374715 0.532 rs3204853 chr15:41689166 C/A cg18705301 chr15:41695430 NDUFAF1 -1.26 -18.66 -0.71 4.38e-54 Ulcerative colitis; LIHC cis rs1801251 1.000 rs67013068 chr2:233608253 G/C cg25237894 chr2:233734115 C2orf82 0.57 10.97 0.51 3.41e-24 Coronary artery disease; LIHC cis rs1046896 0.731 rs9906115 chr17:80791469 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.41 6.12 0.31 2.59e-9 Glycated hemoglobin levels; LIHC cis rs4975709 0.610 rs4975706 chr5:1860365 G/T cg15595755 chr5:1867978 NA 0.41 8.2 0.41 4.95e-15 Cardiovascular disease risk factors; LIHC trans rs916888 0.773 rs199439 chr17:44793503 A/G cg22968622 chr17:43663579 NA 1.19 13.18 0.58 2.25e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9640161 0.750 rs11764936 chr7:150025915 G/T cg17279839 chr7:150038598 RARRES2 0.57 11.67 0.53 1e-26 Blood protein levels;Circulating chemerin levels; LIHC cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg24531977 chr5:56204891 C5orf35 -0.66 -9.43 -0.45 6.3e-19 Initial pursuit acceleration; LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg06873352 chr17:61820015 STRADA 0.75 13.35 0.59 5.02e-33 Prudent dietary pattern; LIHC trans rs10411161 0.702 rs10424202 chr19:52387297 G/A cg22319618 chr22:45562946 NUP50 -0.61 -8.42 -0.41 1.06e-15 Breast cancer; LIHC cis rs904251 0.504 rs12202664 chr6:37481198 A/G cg01843034 chr6:37503916 NA -0.46 -7.9 -0.39 3.82e-14 Cognitive performance; LIHC cis rs4237845 0.715 rs4760340 chr12:58275176 A/T cg04478727 chr12:58166393 METTL1;FAM119B 0.51 7.24 0.36 2.92e-12 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.789 rs7758895 chr6:160193465 T/C cg11366901 chr6:160182831 ACAT2 0.92 15.43 0.64 3.78e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs9910055 0.530 rs2269908 chr17:42294198 G/C cg08499158 chr17:42289980 UBTF -0.48 -7.81 -0.39 7.16e-14 Total body bone mineral density; LIHC cis rs7129220 0.512 rs12279871 chr11:10228196 G/A cg01453529 chr11:10209919 SBF2 -0.43 -7.87 -0.39 4.77e-14 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg03721293 chr16:90014378 DEF8 0.39 6.53 0.33 2.32e-10 Skin colour saturation; LIHC cis rs7103648 0.669 rs10437655 chr11:47391948 G/A cg20307385 chr11:47447363 PSMC3 0.94 15.9 0.65 5.07e-43 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs703842 1.000 rs10431505 chr12:58178589 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.82 13.59 0.59 5.99e-34 Multiple sclerosis; LIHC trans rs877282 0.898 rs11253344 chr10:765162 C/T cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs6964587 0.967 rs10231496 chr7:91741132 T/C cg17063962 chr7:91808500 NA 1.04 20.83 0.75 8.28e-63 Breast cancer; LIHC cis rs919433 0.679 rs10166328 chr2:198511917 A/G cg03934865 chr2:198174659 NA 0.47 7.06 0.36 9.38e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4631830 0.720 rs2125771 chr10:51506957 C/T cg20129853 chr10:51489980 NA -0.39 -8.57 -0.42 3.6e-16 Prostate-specific antigen levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19550733 chr1:25869992 LDLRAP1 -0.51 -6.39 -0.33 5.56e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9896052 0.591 rs11077790 chr17:73464718 G/A cg25649188 chr17:73499917 CASKIN2 0.39 6.44 0.33 4.14e-10 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs629922 0.642 rs531831 chr11:114071814 A/G cg01914181 chr11:114070210 ZBTB16 -0.52 -7.52 -0.38 4.78e-13 Paneth cell defects in Crohn's disease; LIHC cis rs17428076 0.793 rs3765167 chr2:172693944 A/G cg13550731 chr2:172543902 DYNC1I2 0.37 6.14 0.32 2.32e-9 Myopia; LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg22528358 chr1:107598549 PRMT6 -0.62 -9.51 -0.46 3.4e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1008375 0.966 rs3733576 chr4:17586703 T/C cg02297831 chr4:17616191 MED28 0.45 6.13 0.31 2.38e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs5753618 0.583 rs5753632 chr22:31863097 C/T cg02404636 chr22:31891804 SFI1 0.34 6.07 0.31 3.4e-9 Colorectal cancer; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg10150615 chr22:24372951 LOC391322 0.59 8.51 0.42 5.42e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7309 0.935 rs6432674 chr2:162025322 G/T cg13854012 chr2:162103682 NA -0.35 -6.52 -0.33 2.46e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs2072499 0.750 rs909269 chr1:156192028 C/T cg25208724 chr1:156163844 SLC25A44 0.69 7.48 0.38 6.25e-13 Testicular germ cell tumor; LIHC trans rs8073060 0.559 rs17550632 chr17:33890883 G/C cg19694781 chr19:47549865 TMEM160 1.25 12.79 0.57 6.83e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6690583 0.623 rs2083283 chr1:85439996 C/A cg22153463 chr1:85462885 MCOLN2 0.54 6.48 0.33 3.22e-10 Serum sulfate level; LIHC cis rs6831352 0.918 rs7670638 chr4:100059807 G/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs1559088 1.000 rs1559088 chr19:33551061 C/T cg17764715 chr19:33622953 WDR88 0.4 5.77 0.3 1.76e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs8062405 0.755 rs12447461 chr16:28582941 C/A cg07451762 chr16:28383216 NA 0.39 6.93 0.35 2.05e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg12800803 chr20:60717299 PSMA7 -0.47 -6.09 -0.31 3e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg18357526 chr6:26021779 HIST1H4A 1.07 16.1 0.66 8.42e-44 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.48 -8.45 -0.42 8.7e-16 Height; LIHC cis rs9549367 0.713 rs9549681 chr13:113829873 T/C cg00898013 chr13:113819073 PROZ -0.44 -7.39 -0.37 1.17e-12 Platelet distribution width; LIHC cis rs11971779 0.625 rs10260850 chr7:139003602 G/T cg07862535 chr7:139043722 LUC7L2 0.43 6.13 0.31 2.41e-9 Diisocyanate-induced asthma; LIHC cis rs9457247 0.765 rs9459836 chr6:167419105 G/A cg23791538 chr6:167370224 RNASET2 -0.51 -7.72 -0.39 1.27e-13 Crohn's disease; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg18918831 chr3:195489782 MUC4 -0.73 -11.2 -0.52 5.1e-25 Lung disease severity in cystic fibrosis; LIHC cis rs9611565 0.559 rs132761 chr22:42004371 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.67 0.5 4.01e-23 Vitiligo; LIHC cis rs7927592 0.956 rs7106259 chr11:68298512 T/G cg20283391 chr11:68216788 NA -0.51 -7.69 -0.38 1.55e-13 Total body bone mineral density; LIHC cis rs1065656 0.571 rs12149777 chr16:1834724 A/G cg08610935 chr16:1836813 NUBP2 -0.46 -7.21 -0.36 3.6e-12 Insulin-like growth factors; LIHC trans rs10411161 0.810 rs77082285 chr19:52387583 G/A cg22319618 chr22:45562946 NUP50 -0.63 -7.38 -0.37 1.21e-12 Breast cancer; LIHC cis rs763121 0.815 rs9306328 chr22:39028913 C/T cg06022373 chr22:39101656 GTPBP1 0.63 12.35 0.56 3.24e-29 Menopause (age at onset); LIHC cis rs10791323 0.569 rs10750552 chr11:133740141 A/C cg06766960 chr11:133703094 NA 0.4 6.08 0.31 3.23e-9 Childhood ear infection; LIHC cis rs6754311 0.773 rs666407 chr2:136640233 A/G cg07305463 chr2:136567211 LCT -0.39 -7.54 -0.38 4.14e-13 Mosquito bite size; LIHC cis rs7238033 0.624 rs10432193 chr18:43307072 A/G cg20610511 chr18:43302872 SLC14A1 0.39 6.49 0.33 3.03e-10 Bladder cancer; LIHC cis rs10880689 1 rs10880689 chr12:37930102 A/G cg26384229 chr12:38710491 ALG10B 0.81 10.43 0.49 2.66e-22 Resting heart rate; LIHC cis rs7618501 1.000 rs57648519 chr3:49813169 C/A cg24110177 chr3:50126178 RBM5 -0.44 -6.76 -0.34 6.02e-11 Intelligence (multi-trait analysis); LIHC cis rs763121 0.853 rs138702 chr22:39132601 A/T cg21395723 chr22:39101663 GTPBP1 -0.38 -6.34 -0.32 7.09e-10 Menopause (age at onset); LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg13409248 chr3:40428643 ENTPD3 0.49 8.33 0.41 2.04e-15 Renal cell carcinoma; LIHC cis rs4148883 0.603 rs1893883 chr4:100124716 C/G cg12011299 chr4:100065546 ADH4 0.33 6.39 0.33 5.58e-10 Alcohol dependence; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg06812651 chr1:234746099 IRF2BP2 -0.44 -6.1 -0.31 2.8e-9 Alopecia areata; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01089589 chr2:10920095 ATP6V1C2 0.47 6.28 0.32 1.05e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7937682 0.889 rs7948236 chr11:111499933 C/A cg09085632 chr11:111637200 PPP2R1B -1.05 -12.63 -0.56 2.76e-30 Primary sclerosing cholangitis; LIHC cis rs57502260 0.680 rs7104806 chr11:68222188 C/T cg16797656 chr11:68205561 LRP5 0.6 8.0 0.4 1.99e-14 Total body bone mineral density (age 45-60); LIHC cis rs400736 0.930 rs442862 chr1:8079494 T/C cg25007680 chr1:8021821 PARK7 0.59 9.58 0.46 2.03e-19 Response to antidepressants and depression; LIHC cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs733592 0.507 rs3825403 chr12:48457159 G/A cg21466736 chr12:48725269 NA 0.33 5.95 0.31 6.81e-9 Plateletcrit; LIHC cis rs17401966 1.000 rs17410793 chr1:10391886 A/G cg15208524 chr1:10270712 KIF1B 0.45 6.58 0.34 1.8e-10 Hepatocellular carcinoma; LIHC cis rs3770081 0.590 rs60838463 chr2:86443532 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.73 -7.65 -0.38 2.06e-13 Facial emotion recognition (sad faces); LIHC cis rs6564851 0.508 rs7199144 chr16:81251846 A/T cg00908271 chr16:81254010 PKD1L2 -0.3 -6.31 -0.32 8.58e-10 Carotenoid and tocopherol levels; LIHC cis rs769267 0.899 rs67720221 chr19:19440864 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.63 -10.22 -0.48 1.37e-21 Tonsillectomy; LIHC cis rs1348850 0.567 rs3770005 chr2:178528874 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 8.0 0.4 1.99e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1577917 0.876 rs12212808 chr6:86533972 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs2839186 0.504 rs4347941 chr21:47938239 T/C cg12379764 chr21:47803548 PCNT 0.72 12.0 0.54 6.21e-28 Testicular germ cell tumor; LIHC cis rs77633900 0.614 rs2468123 chr15:76931345 T/C cg21673338 chr15:77095150 SCAPER -0.49 -7.36 -0.37 1.42e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs1801251 1.000 rs1446308 chr2:233639309 T/C cg25237894 chr2:233734115 C2orf82 0.58 11.42 0.53 8.57e-26 Coronary artery disease; LIHC cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg11764359 chr7:65958608 NA 0.57 5.82 0.3 1.39e-8 Diabetic kidney disease; LIHC cis rs4332037 0.805 rs10278591 chr7:1921362 A/G cg23043544 chr7:2124092 MAD1L1 0.37 5.77 0.3 1.81e-8 Bipolar disorder; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs2239547 0.603 rs4687698 chr3:53097108 C/T cg11645453 chr3:52864694 ITIH4 0.28 6.97 0.35 1.6e-11 Schizophrenia; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg05484376 chr2:27715224 FNDC4 0.37 6.41 0.33 4.8e-10 Total body bone mineral density; LIHC cis rs9896933 0.708 rs9908751 chr17:80791830 C/T cg20578329 chr17:80767326 TBCD 0.59 6.3 0.32 9.33e-10 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs17106184 1.000 rs11205771 chr1:51276490 A/G cg07174182 chr1:51127561 FAF1 -0.64 -7.07 -0.36 8.58e-12 Type 2 diabetes; LIHC cis rs17106184 1.000 rs1846522 chr1:50981205 G/A cg07174182 chr1:51127561 FAF1 -0.66 -6.96 -0.35 1.76e-11 Type 2 diabetes; LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg18538332 chr22:24372958 LOC391322 -0.68 -9.91 -0.47 1.64e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs7107174 0.892 rs2510042 chr11:77923665 C/T cg02023728 chr11:77925099 USP35 0.46 8.49 0.42 6.6e-16 Testicular germ cell tumor; LIHC cis rs1577917 0.740 rs2842604 chr6:86336300 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.96 -0.4 2.51e-14 Response to antipsychotic treatment; LIHC trans rs79976124 0.842 rs7760550 chr6:66628788 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.88 0.35 2.9e-11 Type 2 diabetes; LIHC cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg06418219 chr1:154948305 SHC1;CKS1B -0.49 -6.96 -0.35 1.71e-11 Prostate cancer; LIHC cis rs875971 1.000 rs6963646 chr7:65685767 T/C cg11764359 chr7:65958608 NA -0.88 -15.37 -0.64 6.43e-41 Aortic root size; LIHC cis rs7238033 0.686 rs3819177 chr18:43316110 T/C cg20610511 chr18:43302872 SLC14A1 0.4 6.61 0.34 1.43e-10 Bladder cancer; LIHC cis rs72843506 0.722 rs74255387 chr17:20101383 G/A cg12065943 chr17:19881925 AKAP10 -0.39 -6.18 -0.32 1.8e-9 Schizophrenia; LIHC cis rs6547741 0.935 rs56001553 chr2:27859926 C/T cg27432699 chr2:27873401 GPN1 -0.8 -13.14 -0.58 3.17e-32 Oral cavity cancer; LIHC cis rs10504229 0.679 rs60869047 chr8:58053221 G/A cg02290350 chr8:58132656 NA 0.31 6.9 0.35 2.57e-11 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.862 rs4721167 chr7:1933224 C/T cg02951883 chr7:2050386 MAD1L1 -0.6 -9.04 -0.44 1.19e-17 Bipolar disorder and schizophrenia; LIHC trans rs783540 1.000 rs783531 chr15:83249119 C/T cg18393722 chr15:85113863 UBE2QP1 -0.39 -6.79 -0.34 4.83e-11 Schizophrenia; LIHC cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9527 0.637 rs11191424 chr10:104625886 G/A cg15744005 chr10:104629667 AS3MT -0.42 -9.45 -0.46 5.54e-19 Arsenic metabolism; LIHC cis rs796364 0.806 rs4673634 chr2:200863349 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.79 8.79 0.43 7.61e-17 Schizophrenia; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg18538332 chr22:24372958 LOC391322 -0.65 -9.7 -0.46 8.19e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3791556 0.581 rs6543514 chr2:240096690 T/C cg03281426 chr2:240109471 HDAC4 0.39 6.12 0.31 2.57e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs12908161 1.000 rs12903134 chr15:85337699 T/A cg12863693 chr15:85201151 NMB 0.44 6.34 0.32 7.18e-10 Schizophrenia; LIHC cis rs7959452 0.640 rs4274230 chr12:69700772 T/G cg20891283 chr12:69753455 YEATS4 0.81 15.49 0.64 2.22e-41 Blood protein levels; LIHC cis rs1401999 1.000 rs3805108 chr3:183691650 T/C cg05044414 chr3:183734942 ABCC5 0.34 5.99 0.31 5.34e-9 Anterior chamber depth; LIHC cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.64 -0.38 2.21e-13 Bipolar disorder; LIHC cis rs11098499 0.754 rs28652763 chr4:120242312 C/T cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC trans rs7618501 0.633 rs11130228 chr3:50003246 C/T cg21659725 chr3:3221576 CRBN 0.67 11.05 0.51 1.82e-24 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.731 rs2156463 chr11:68386311 T/C cg16797656 chr11:68205561 LRP5 0.5 8.72 0.43 1.19e-16 Total body bone mineral density; LIHC cis rs4727027 0.933 rs10238826 chr7:148830888 A/G cg23583168 chr7:148888333 NA -0.73 -10.34 -0.49 5.46e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7772486 0.558 rs9376965 chr6:146130055 G/A cg13319975 chr6:146136371 FBXO30 -0.56 -8.75 -0.43 1.01e-16 Lobe attachment (rater-scored or self-reported); LIHC trans rs9929218 0.731 rs72785179 chr16:68767912 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -9.34 -0.45 1.28e-18 Colorectal cancer; LIHC cis rs8067545 0.611 rs2703781 chr17:20144714 A/G cg13482628 chr17:19912719 NA -0.42 -6.93 -0.35 2.05e-11 Schizophrenia; LIHC cis rs17286411 0.750 rs2288030 chr16:71914107 G/A cg06353428 chr16:71660113 MARVELD3 0.56 7.06 0.36 9.2e-12 Blood protein levels; LIHC cis rs7618501 1.000 rs6802890 chr3:49832261 A/G cg24110177 chr3:50126178 RBM5 -0.44 -6.8 -0.35 4.71e-11 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs6701037 0.566 rs1014555 chr1:175134249 C/T cg17845761 chr1:175162550 KIAA0040 0.41 6.96 0.35 1.76e-11 Alcohol dependence; LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg22663859 chr13:21900854 NA 0.5 8.17 0.4 5.87e-15 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs57221529 0.766 rs72703042 chr5:579269 C/T cg09021430 chr5:549028 NA -0.45 -8.73 -0.43 1.14e-16 Lung disease severity in cystic fibrosis; LIHC cis rs12142240 0.698 rs6659228 chr1:46811027 C/G cg14993813 chr1:46806288 NSUN4 -0.66 -6.18 -0.32 1.77e-9 Menopause (age at onset); LIHC cis rs4808199 0.947 rs2099333 chr19:19605963 C/T cg03709012 chr19:19516395 GATAD2A 1.08 19.43 0.72 3.44e-57 Nonalcoholic fatty liver disease; LIHC cis rs600806 0.713 rs11102984 chr1:109997373 T/C cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.61 -0.38 2.77e-13 Intelligence (multi-trait analysis); LIHC cis rs4908768 0.906 rs11584261 chr1:8560366 C/A cg25722041 chr1:8623473 RERE 0.41 5.88 0.3 1e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs1422110 0.513 rs1422105 chr5:85448371 A/C cg01787110 chr1:109008453 NBPF6 0.3 7.55 0.38 3.92e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.43 6.04 0.31 4.1e-9 Electroencephalogram traits; LIHC cis rs8114671 0.562 rs6087644 chr20:33480917 G/C cg07148914 chr20:33460835 GGT7 0.66 10.08 0.48 4.43e-21 Height; LIHC cis rs1799949 0.965 rs8070179 chr17:41202688 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.08 0.31 3.16e-9 Menopause (age at onset); LIHC cis rs1165668 0.755 rs10735390 chr12:104311731 A/G cg21863207 chr12:104234989 NT5DC3 0.46 8.01 0.4 1.76e-14 Coronary heart disease (SNP X SNP interaction); LIHC cis rs2576037 0.583 rs12386118 chr18:44540376 C/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.79 -0.3 1.62e-8 Personality dimensions; LIHC cis rs8180040 1.000 rs295428 chr3:47359262 G/T cg02527881 chr3:46936655 PTH1R -0.31 -6.03 -0.31 4.15e-9 Colorectal cancer; LIHC cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.16 17.99 0.7 2.16e-51 Gut microbiome composition (summer); LIHC cis rs561341 0.941 rs4795664 chr17:30233467 C/T cg13647721 chr17:30228624 UTP6 0.8 7.65 0.38 2.07e-13 Hip circumference adjusted for BMI; LIHC cis rs244731 0.919 rs12652509 chr5:176626441 A/G cg17509989 chr5:176798049 RGS14 -0.67 -6.26 -0.32 1.14e-9 Urate levels in lean individuals; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00162751 chr1:220921532 MOSC2 0.38 6.19 0.32 1.74e-9 Pancreatic cancer; LIHC cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs11958404 0.932 rs10045597 chr5:157451963 T/C cg05962755 chr5:157440814 NA 0.9 10.6 0.5 6.7e-23 IgG glycosylation; LIHC cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg12310025 chr6:25882481 NA -0.95 -12.37 -0.56 2.64e-29 Intelligence (multi-trait analysis); LIHC cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg05552183 chr6:42928497 GNMT 0.64 9.44 0.45 6.05e-19 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs240764 0.658 rs12664626 chr6:101195720 A/G cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.34e-9 Neuroticism; LIHC cis rs7756236 0.521 rs6907793 chr6:36625206 A/G cg08179530 chr6:36648295 CDKN1A 0.42 6.35 0.32 7e-10 QRS duration; LIHC cis rs7208859 0.573 rs4055105 chr17:29102550 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.23e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs763121 0.888 rs2235229 chr22:39124912 A/G cg14440974 chr22:39074834 NA -0.34 -5.89 -0.3 9.23e-9 Menopause (age at onset); LIHC trans rs875971 0.964 rs778735 chr7:65814809 C/A cg10756647 chr7:56101905 PSPH 0.44 6.49 0.33 3.09e-10 Aortic root size; LIHC cis rs9560113 0.959 rs9555803 chr13:112179560 G/T cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs780096 0.546 rs2293571 chr2:27729480 C/T cg27432699 chr2:27873401 GPN1 -0.57 -8.3 -0.41 2.46e-15 Total body bone mineral density; LIHC cis rs11583043 0.957 rs6577223 chr1:101499750 G/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 5.96 0.31 6.44e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs3736485 0.966 rs28428679 chr15:51913040 A/G cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.56e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1008375 1.000 rs12507142 chr4:17656103 A/G cg16339924 chr4:17578868 LAP3 0.44 6.16 0.32 1.99e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg20887711 chr4:1340912 KIAA1530 0.6 9.34 0.45 1.23e-18 Obesity-related traits; LIHC cis rs2239547 0.603 rs7644973 chr3:53082937 C/T cg11645453 chr3:52864694 ITIH4 0.26 6.34 0.32 7.21e-10 Schizophrenia; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01782320 chr10:27443404 YME1L1;MASTL -0.43 -6.5 -0.33 2.84e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs4820539 0.932 rs3788349 chr22:23467950 A/G cg21100191 chr22:23484243 RTDR1 0.91 16.53 0.67 1.58e-45 Bone mineral density; LIHC cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs807029 0.577 rs3740489 chr10:102754238 A/G cg25179470 chr10:102756915 LZTS2 0.44 6.1 0.31 2.91e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs8078723 0.802 rs9303283 chr17:38192633 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.51 -8.12 -0.4 8.59e-15 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03736562 chr6:100016731 CCNC -0.43 -6.25 -0.32 1.24e-9 Pancreatic cancer; LIHC cis rs507080 0.922 rs12577485 chr11:118547503 C/A cg04173919 chr11:118528438 PHLDB1 0.31 5.84 0.3 1.21e-8 Serum metabolite levels; LIHC cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.25 -0.45 2.55e-18 Bipolar disorder; LIHC cis rs10979 0.965 rs9496674 chr6:143886106 G/T cg25407410 chr6:143891975 LOC285740 -0.37 -5.85 -0.3 1.13e-8 Hypospadias; LIHC cis rs7267979 1.000 rs2258769 chr20:25276680 G/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs4820294 0.516 rs12484441 chr22:38097359 C/G cg26138144 chr22:38071188 LGALS1 0.71 10.43 0.49 2.63e-22 Fat distribution (HIV); LIHC cis rs11098499 0.687 rs71610270 chr4:120287436 A/G cg09307838 chr4:120376055 NA 0.64 9.69 0.46 8.58e-20 Corneal astigmatism; LIHC cis rs7116495 0.881 rs7930544 chr11:71737354 C/T cg26138937 chr11:71823887 C11orf51 -0.81 -8.04 -0.4 1.43e-14 Severe influenza A (H1N1) infection; LIHC cis rs7666738 0.753 rs10029372 chr4:98859002 T/C cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC trans rs873946 0.504 rs12775990 chr10:134575836 C/T cg02418909 chr7:4811322 NA -0.46 -6.16 -0.32 1.99e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2576037 0.583 rs593340 chr18:44418346 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.94 0.51 4.41e-24 Personality dimensions; LIHC trans rs4566357 0.615 rs4675139 chr2:227908527 G/A cg16088116 chr21:44841560 SIK1 -0.41 -6.37 -0.33 6.25e-10 Coronary artery disease; LIHC cis rs9341808 0.754 rs9352817 chr6:81025879 T/G cg08355045 chr6:80787529 NA 0.33 6.82 0.35 4.12e-11 Sitting height ratio; LIHC cis rs11018874 0.709 rs10830428 chr11:89894294 C/G cg05041596 chr11:89867385 NAALAD2 -0.39 -6.35 -0.32 6.91e-10 White blood cell types; LIHC cis rs17666538 0.585 rs336444 chr8:633123 C/G cg02524346 chr8:600233 NA -0.59 -5.92 -0.31 7.69e-9 IgG glycosylation; LIHC cis rs10503871 0.690 rs4147357 chr8:30344444 T/C cg26383811 chr8:30366931 RBPMS 0.43 7.48 0.37 6.46e-13 Metabolite levels (X-11787); LIHC cis rs4721295 0.573 rs3779000 chr7:2181628 G/A cg21782813 chr7:2030301 MAD1L1 0.37 6.33 0.32 7.88e-10 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs1799949 0.894 rs36062488 chr17:41337472 C/T cg25072359 chr17:41440525 NA -0.37 -5.99 -0.31 5.35e-9 Menopause (age at onset); LIHC cis rs10789491 1.000 rs1371834 chr1:47176894 G/A cg15501359 chr1:47185051 KIAA0494 0.78 11.05 0.51 1.79e-24 Response to hepatitis C treatment; LIHC cis rs55665837 0.540 rs1007392 chr11:14774591 A/G cg00085434 chr11:14927489 NA 0.41 5.82 0.3 1.37e-8 Vitamin D levels; LIHC trans rs60843830 1.000 rs17713396 chr2:227201 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.57 7.86 0.39 4.9e-14 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.91 -0.3 8.13e-9 Total body bone mineral density; LIHC cis rs3741404 0.825 rs2845597 chr11:63954370 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.93 15.93 0.65 4.13e-43 Platelet count; LIHC cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg08499158 chr17:42289980 UBTF -0.53 -9.25 -0.45 2.58e-18 Total body bone mineral density; LIHC trans rs12478296 1.000 rs55777943 chr2:243040686 T/C cg01596870 chr19:55963115 NA -0.62 -7.38 -0.37 1.23e-12 Obesity-related traits; LIHC cis rs10751667 0.580 rs7396041 chr11:1001607 G/A cg10932868 chr11:921992 NA 0.33 6.16 0.32 2.05e-9 Alzheimer's disease (late onset); LIHC cis rs7772486 0.875 rs2748485 chr6:146332421 T/C cg23711669 chr6:146136114 FBXO30 0.66 11.81 0.54 3.2e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs1555322 0.530 rs7004 chr20:33866753 G/C cg03689076 chr20:33865952 NA 0.58 6.65 0.34 1.16e-10 Attention deficit hyperactivity disorder; LIHC cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg21724239 chr8:58056113 NA -0.55 -6.96 -0.35 1.73e-11 Developmental language disorder (linguistic errors); LIHC cis rs12086130 0.892 rs72904788 chr1:51415247 T/G cg07174182 chr1:51127561 FAF1 -0.75 -7.9 -0.39 3.96e-14 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs12200782 1.000 rs72844495 chr6:26610640 T/C cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs3736485 0.966 rs7177471 chr15:51911232 C/T cg08986416 chr15:51914746 DMXL2 -0.45 -6.73 -0.34 7.21e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6998277 1.000 rs16869658 chr8:103633762 C/T cg10187029 chr8:103597600 NA 0.58 7.6 0.38 2.94e-13 Migraine; LIHC cis rs8072100 0.811 rs9889709 chr17:45445229 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.72 -0.3 2.34e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs826838 0.967 rs1719852 chr12:39128531 A/G cg26384229 chr12:38710491 ALG10B -0.6 -8.66 -0.42 1.92e-16 Heart rate; LIHC trans rs208520 0.526 rs4710310 chr6:66802808 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.05 -20.78 -0.75 1.27e-62 Exhaled nitric oxide output; LIHC trans rs11098499 0.908 rs28499576 chr4:120386677 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.81 0.47 3.63e-20 Corneal astigmatism; LIHC cis rs2991971 0.903 rs2991973 chr1:46020632 G/A cg15605315 chr1:45957053 TESK2 0.47 6.26 0.32 1.17e-9 High light scatter reticulocyte count; LIHC cis rs1008375 0.931 rs2315558 chr4:17674558 C/A cg02297831 chr4:17616191 MED28 0.41 6.59 0.34 1.7e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6952808 0.564 rs73038441 chr7:2139286 T/C cg21782813 chr7:2030301 MAD1L1 0.38 6.56 0.33 2.04e-10 Bipolar disorder and schizophrenia; LIHC cis rs13108904 0.901 rs4974594 chr4:1300480 C/T cg26831259 chr4:1366826 KIAA1530 0.36 6.0 0.31 5.14e-9 Obesity-related traits; LIHC cis rs748404 0.631 rs7166812 chr15:43644760 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.55 9.73 0.47 6.35e-20 Lung cancer; LIHC cis rs7772486 0.686 rs7739735 chr6:146123536 G/A cg23711669 chr6:146136114 FBXO30 0.64 11.51 0.53 3.76e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs66573146 0.656 rs56094305 chr4:6956086 C/T cg15105060 chr4:7024189 TBC1D14 -0.68 -6.1 -0.31 2.88e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7772486 0.790 rs2253654 chr6:146199445 T/C cg13319975 chr6:146136371 FBXO30 -0.38 -6.25 -0.32 1.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs332507 0.673 rs2242426 chr3:124398031 A/G cg05980111 chr3:124395277 KALRN 0.46 7.07 0.36 8.83e-12 Plateletcrit; LIHC cis rs7312774 1.000 rs7312774 chr12:107305728 G/A cg16260113 chr12:107380972 MTERFD3 0.77 10.08 0.48 4.37e-21 Severe influenza A (H1N1) infection; LIHC cis rs2576037 0.526 rs2032215 chr18:44439011 A/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.5 -7.37 -0.37 1.26e-12 Personality dimensions; LIHC cis rs7208859 0.673 rs73277967 chr17:29184166 T/A cg14067834 chr17:29058358 SUZ12P 0.67 6.54 0.33 2.2e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9611565 0.506 rs2024566 chr22:41697338 A/G cg03806693 chr22:41940476 POLR3H -0.7 -8.33 -0.41 2.01e-15 Vitiligo; LIHC cis rs7647973 0.961 rs4955430 chr3:49378088 G/A cg07636037 chr3:49044803 WDR6 0.51 6.18 0.32 1.82e-9 Menarche (age at onset); LIHC cis rs6500602 0.634 rs2270365 chr16:4526758 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.74 0.3 2.12e-8 Schizophrenia; LIHC cis rs2404602 0.647 rs12910820 chr15:77022825 T/C cg03037974 chr15:76606532 NA -0.61 -10.28 -0.49 8.59e-22 Blood metabolite levels; LIHC cis rs9457247 0.765 rs10946203 chr6:167446735 A/C cg12798992 chr6:167411361 FGFR1OP 0.48 7.19 0.36 4.22e-12 Crohn's disease; LIHC cis rs35306767 0.714 rs12783621 chr10:1083304 C/T cg26597838 chr10:835615 NA 0.57 6.4 0.33 5.1e-10 Eosinophil percentage of granulocytes; LIHC cis rs7927771 0.864 rs3781626 chr11:47442893 A/T cg20135002 chr11:47629003 NA -0.53 -8.99 -0.44 1.73e-17 Subjective well-being; LIHC cis rs365132 1.000 rs1700490 chr5:176402401 G/A cg16309518 chr5:176445507 NA -0.58 -11.49 -0.53 4.46e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs1559088 0.600 rs7256470 chr19:33558085 C/A cg17764715 chr19:33622953 WDR88 0.54 7.21 0.36 3.73e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2303745 0.589 rs1465576 chr19:17398487 G/A cg04248312 chr19:17393744 ANKLE1 -0.73 -11.87 -0.54 1.93e-27 Systemic lupus erythematosus; LIHC cis rs2257205 0.667 rs7220884 chr17:56743948 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.79 0.39 8.05e-14 Pancreatic cancer; LIHC cis rs7208859 0.623 rs9890862 chr17:29125450 C/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10751667 0.961 rs7479171 chr11:926809 G/A cg10932868 chr11:921992 NA 0.37 6.84 0.35 3.76e-11 Alzheimer's disease (late onset); LIHC cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.63 0.38 2.39e-13 Bipolar disorder; LIHC cis rs6998277 1.000 rs4281092 chr8:103647956 A/G cg10187029 chr8:103597600 NA -0.74 -8.79 -0.43 7.29e-17 Migraine; LIHC trans rs916888 0.687 rs199456 chr17:44797919 C/T cg26692224 chr17:62915920 LRRC37A3 -0.73 -6.94 -0.35 1.93e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs12477438 0.520 rs13004491 chr2:99738008 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.05 0.6 1.02e-35 Chronic sinus infection; LIHC cis rs6500602 0.727 rs4786509 chr16:4568769 C/G cg08645402 chr16:4508243 NA -0.42 -7.77 -0.39 9.12e-14 Schizophrenia; LIHC cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg18404041 chr3:52824283 ITIH1 -0.58 -9.69 -0.46 8.83e-20 Electroencephalogram traits; LIHC cis rs589448 0.902 rs642786 chr12:69758462 T/C cg14784868 chr12:69753453 YEATS4 0.98 22.82 0.78 1.07e-70 Cerebrospinal fluid biomarker levels; LIHC cis rs477692 1.000 rs553371 chr10:131413676 T/C cg19680672 chr10:131412579 MGMT -0.45 -6.8 -0.35 4.63e-11 Response to temozolomide; LIHC cis rs7116495 0.609 rs10501408 chr11:71680590 C/T cg26138937 chr11:71823887 C11orf51 -1.28 -10.28 -0.49 8.92e-22 Severe influenza A (H1N1) infection; LIHC cis rs1534166 0.647 rs9853615 chr3:133519981 C/T cg12373951 chr3:133503437 NA 0.5 7.3 0.37 1.99e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs11229555 0.645 rs11229463 chr11:58210147 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs12928939 0.517 rs71384782 chr16:71978591 A/G cg03805757 chr16:71968109 PKD1L3 -0.96 -13.14 -0.58 3.22e-32 Post bronchodilator FEV1; LIHC cis rs909341 0.818 rs67468102 chr20:62344883 G/C cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.56e-11 Atopic dermatitis; LIHC cis rs7810240 0.762 rs10282108 chr7:150082610 A/G cg10018233 chr7:150070692 REPIN1 -0.41 -6.38 -0.33 5.75e-10 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; LIHC cis rs9616064 0.531 rs9616086 chr22:47050744 G/A cg05621596 chr22:47072043 GRAMD4 -0.7 -10.8 -0.5 1.39e-23 Urate levels in obese individuals; LIHC cis rs7945705 0.935 rs11042102 chr11:8882164 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.43 7.26 0.37 2.58e-12 Hemoglobin concentration; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs75557865 1 rs75557865 chr3:121652141 G/A cg20356878 chr3:121714668 ILDR1 0.42 7.51 0.38 5.16e-13 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9308433 0.529 rs4655243 chr1:214497291 A/G cg06198575 chr1:214491504 SMYD2 0.56 5.92 0.3 7.86e-9 IgG glycosylation; LIHC cis rs10089 1.000 rs10060390 chr5:127452947 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.03e-11 Ileal carcinoids; LIHC cis rs7208859 0.623 rs59029591 chr17:29235746 A/C cg14067834 chr17:29058358 SUZ12P 0.69 6.65 0.34 1.16e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg08280861 chr8:58055591 NA 0.53 6.57 0.33 1.87e-10 Developmental language disorder (linguistic errors); LIHC cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 7.25 0.36 2.87e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs10857712 0.754 rs2297032 chr10:135234580 C/T cg19623624 chr10:135278901 LOC619207 -0.45 -6.99 -0.35 1.45e-11 Systemic lupus erythematosus; LIHC trans rs526821 0.595 rs2926309 chr11:55314219 G/A cg15704280 chr7:45808275 SEPT13 -0.5 -7.63 -0.38 2.31e-13 Pediatric bone mineral density (spine); LIHC trans rs8002861 0.902 rs1445557 chr13:44464827 C/T cg17145862 chr1:211918768 LPGAT1 0.67 13.31 0.58 7.28e-33 Leprosy; LIHC cis rs61160187 0.503 rs248911 chr5:59847538 T/C cg02684056 chr5:59996105 DEPDC1B 0.39 5.98 0.31 5.53e-9 Educational attainment (years of education);Educational attainment (college completion); LIHC cis rs2576037 0.501 rs7245049 chr18:44528213 G/A cg19077165 chr18:44547161 KATNAL2 -0.43 -6.62 -0.34 1.38e-10 Personality dimensions; LIHC cis rs9911578 1.000 rs7223955 chr17:56917053 C/A cg05425664 chr17:57184151 TRIM37 -0.59 -8.83 -0.43 5.37e-17 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.505 rs200935 chr10:38132810 T/A cg00409905 chr10:38381863 ZNF37A -0.55 -9.5 -0.46 3.75e-19 Extrinsic epigenetic age acceleration; LIHC cis rs1355223 0.902 rs11603774 chr11:34732891 G/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg00684032 chr4:1343700 KIAA1530 0.5 7.29 0.37 2.22e-12 Obesity-related traits; LIHC cis rs3020736 0.500 rs4147640 chr22:42485292 T/C cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs782590 0.694 rs2627775 chr2:55877113 C/T cg03859395 chr2:55845619 SMEK2 0.83 13.68 0.59 2.85e-34 Metabolic syndrome; LIHC cis rs2108225 0.837 rs6466186 chr7:107446966 G/C cg18560240 chr7:107437656 SLC26A3 -0.41 -6.39 -0.33 5.4e-10 Ulcerative colitis; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg04234412 chr22:24373322 LOC391322 -0.76 -11.48 -0.53 4.99e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs174601 0.861 rs174584 chr11:61610750 G/A cg27386326 chr11:61587980 NA 0.64 13.6 0.59 5.78e-34 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs1639906 0.507 rs1004643 chr7:2185324 G/C cg02951883 chr7:2050386 MAD1L1 0.6 8.24 0.41 3.83e-15 Colonoscopy-negative controls vs population controls; LIHC cis rs769267 0.930 rs10419912 chr19:19597055 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 -0.38 -5.79 -0.3 1.61e-8 Tonsillectomy; LIHC cis rs7487075 0.619 rs10785629 chr12:46854727 G/A cg23829395 chr12:46796953 NA 0.34 5.94 0.31 6.95e-9 Itch intensity from mosquito bite; LIHC cis rs8141529 0.551 rs34578331 chr22:29347215 G/T cg15103426 chr22:29168792 CCDC117 0.44 6.2 0.32 1.63e-9 Lymphocyte counts; LIHC cis rs7833790 0.724 rs4739627 chr8:82734657 A/G cg17211192 chr8:82754475 SNX16 -0.58 -10.57 -0.5 8.77e-23 Diastolic blood pressure; LIHC cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7833790 0.724 rs12676336 chr8:82771008 C/T cg17211192 chr8:82754475 SNX16 0.58 10.61 0.5 6.24e-23 Diastolic blood pressure; LIHC cis rs4595586 0.545 rs12828790 chr12:39401043 G/A cg26384229 chr12:38710491 ALG10B 0.48 5.92 0.3 7.94e-9 Morning vs. evening chronotype; LIHC cis rs7188697 0.922 rs37053 chr16:58558707 T/C cg02549819 chr16:58548995 SETD6 -0.46 -7.21 -0.36 3.65e-12 QT interval; LIHC cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg11766577 chr21:47581405 C21orf56 -0.45 -7.41 -0.37 1.02e-12 Testicular germ cell tumor; LIHC cis rs4474465 0.688 rs4945300 chr11:78282632 T/C cg27205649 chr11:78285834 NARS2 0.49 7.74 0.39 1.11e-13 Alzheimer's disease (survival time); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18580865 chr12:93323267 EEA1 -0.38 -6.1 -0.31 2.82e-9 Pancreatic cancer; LIHC cis rs826838 0.967 rs11168985 chr12:39045983 A/C cg13010199 chr12:38710504 ALG10B -0.52 -6.48 -0.33 3.24e-10 Heart rate; LIHC cis rs7395581 0.918 rs10501321 chr11:47294626 A/G cg25783544 chr11:47291846 MADD 0.41 5.85 0.3 1.16e-8 HDL cholesterol; LIHC cis rs3008870 0.959 rs2985826 chr1:67412918 G/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs644799 1.000 rs623191 chr11:95548359 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.82 0.47 3.16e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg27555944 chr3:49056208 DALRD3 -0.45 -6.23 -0.32 1.37e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7309 0.935 rs1921309 chr2:162048975 T/A cg22496339 chr2:162101262 NA 0.81 13.56 0.59 7.91e-34 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs1046896 0.586 rs9897951 chr17:80810662 T/C cg02711726 chr17:80685570 FN3KRP -0.44 -8.23 -0.41 4.06e-15 Glycated hemoglobin levels; LIHC cis rs9921222 0.500 rs11648673 chr16:377794 G/A cg08923669 chr16:420230 MRPL28 -0.47 -6.2 -0.32 1.67e-9 Bone mineral density (spine);Bone mineral density; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08628601 chr15:52861409 ARPP19 0.48 6.32 0.32 7.97e-10 Lung function (FEV1/FVC); LIHC cis rs2204008 0.837 rs12369089 chr12:38060263 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs4908768 0.906 rs12409937 chr1:8538302 G/C cg20416874 chr1:8611966 RERE 0.57 9.07 0.44 9.19e-18 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs970548 0.697 rs11239534 chr10:45968590 A/T cg14222797 chr10:16859974 RSU1 0.54 6.42 0.33 4.51e-10 Total cholesterol levels;Cholesterol, total;HDL cholesterol;HDL cholesterol levels; LIHC cis rs4665809 1.000 rs2384322 chr2:26291146 C/G cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.36 -0.45 1.07e-18 Gut microbiome composition (summer); LIHC cis rs7193541 0.684 rs4888264 chr16:74681632 T/G cg01733217 chr16:74700730 RFWD3 0.92 22.69 0.78 3.35e-70 Multiple myeloma; LIHC trans rs2211698 0.881 rs4817655 chr21:35841020 C/G cg18044562 chr7:50468399 IKZF1 0.52 7.29 0.37 2.18e-12 Cancer; LIHC cis rs7927592 0.913 rs11228268 chr11:68287447 A/T cg01657329 chr11:68192670 LRP5 -0.46 -5.99 -0.31 5.25e-9 Total body bone mineral density; LIHC cis rs11098499 0.874 rs6826823 chr4:120112098 G/C cg09307838 chr4:120376055 NA 0.53 7.74 0.39 1.15e-13 Corneal astigmatism; LIHC cis rs4934494 0.768 rs17126269 chr10:91454731 C/A cg19698084 chr10:91461284 KIF20B -0.49 -6.51 -0.33 2.69e-10 Red blood cell count; LIHC cis rs651907 0.535 rs12631513 chr3:101517476 A/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs7726839 0.540 rs58599998 chr5:596087 A/G cg09021430 chr5:549028 NA -0.42 -8.36 -0.41 1.65e-15 Obesity-related traits; LIHC cis rs10493773 0.609 rs2389972 chr1:86190666 A/G cg17807903 chr1:86174739 ZNHIT6 -0.6 -11.73 -0.54 6.28e-27 Urate levels in overweight individuals; LIHC cis rs11758351 1.000 rs78012445 chr6:26195080 G/C cg03854865 chr6:26224070 HIST1H3E 0.63 7.07 0.36 8.82e-12 Gout;Renal underexcretion gout; LIHC cis rs79057730 0.599 rs4721086 chr7:821123 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.75 8.7 0.43 1.45e-16 Initial pursuit acceleration; LIHC cis rs4141404 0.781 rs4820945 chr22:31549155 T/C cg07713946 chr22:31675144 LIMK2 -0.34 -5.79 -0.3 1.58e-8 Paclitaxel-induced neuropathy; LIHC cis rs11098499 0.954 rs6838814 chr4:120392443 G/A cg09307838 chr4:120376055 NA 0.77 12.18 0.55 1.32e-28 Corneal astigmatism; LIHC cis rs2997447 0.655 rs2275949 chr1:26385150 C/G cg19633962 chr1:26362018 EXTL1 -0.63 -7.94 -0.39 3.03e-14 QRS complex (12-leadsum); LIHC cis rs2153535 0.580 rs6912374 chr6:8456423 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs611744 0.647 rs589347 chr8:109253929 T/A cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs11098499 0.754 rs7689729 chr4:120256192 A/G cg09307838 chr4:120376055 NA 0.7 11.05 0.51 1.72e-24 Corneal astigmatism; LIHC cis rs2153535 0.601 rs2327059 chr6:8447071 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.04 0.4 1.5e-14 Motion sickness; LIHC cis rs929354 0.742 rs3808316 chr7:156944787 C/G cg17757837 chr7:157058334 UBE3C 0.72 11.83 0.54 2.58e-27 Body mass index; LIHC trans rs12310956 0.532 rs11052930 chr12:33964824 A/G cg26384229 chr12:38710491 ALG10B 0.54 7.31 0.37 1.85e-12 Morning vs. evening chronotype; LIHC cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.6 0.53 1.87e-26 Alzheimer's disease; LIHC cis rs9640161 0.871 rs56156367 chr7:150047201 A/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.45 -7.4 -0.37 1.09e-12 Blood protein levels;Circulating chemerin levels; LIHC cis rs3020736 0.500 rs6002618 chr22:42507859 G/C cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.2 -0.32 1.67e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg07677032 chr17:61819896 STRADA 0.41 5.86 0.3 1.12e-8 Prudent dietary pattern; LIHC cis rs7075426 0.669 rs11202042 chr10:88237104 T/C cg07322936 chr10:88137208 NA 0.48 6.29 0.32 9.59e-10 Migraine without aura; LIHC cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.83 8.71 0.43 1.34e-16 Platelet count; LIHC cis rs7408868 0.831 rs7249115 chr19:15280765 A/G cg09752223 chr19:15281200 NOTCH3 -0.36 -6.26 -0.32 1.18e-9 Pulse pressure; LIHC trans rs875971 1.000 rs12698523 chr7:65968113 C/G cg10756647 chr7:56101905 PSPH 0.44 6.43 0.33 4.25e-10 Aortic root size; LIHC cis rs1801251 1.000 rs7592717 chr2:233577038 G/A cg08000102 chr2:233561755 GIGYF2 0.77 11.45 0.53 6.32e-26 Coronary artery disease; LIHC cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg21016266 chr12:122356598 WDR66 0.51 7.14 0.36 5.74e-12 Mean corpuscular volume; LIHC trans rs9641123 0.639 rs2677086 chr7:93208570 G/T cg09745688 chr16:2908918 PRSS22 -0.36 -6.33 -0.32 7.77e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs7914558 0.646 rs11191459 chr10:104662118 G/A cg15744005 chr10:104629667 AS3MT -0.34 -7.16 -0.36 5.12e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3845702 1.000 rs3768837 chr2:180835792 T/A cg01881094 chr2:180872142 CWC22 -0.45 -5.78 -0.3 1.72e-8 Schizophrenia; LIHC cis rs644799 0.932 rs480079 chr11:95643777 A/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.62 -8.69 -0.43 1.57e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg14503165 chr17:2202686 SMG6 0.41 6.09 0.31 3.01e-9 Immature fraction of reticulocytes; LIHC cis rs6882046 0.513 rs185291 chr5:88006764 T/C cg22951263 chr5:87985283 NA -0.37 -6.53 -0.33 2.34e-10 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs7572733 0.534 rs700684 chr2:198713099 C/T cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs919433 0.680 rs2565160 chr2:198286474 A/G cg03934865 chr2:198174659 NA 0.55 8.38 0.41 1.42e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs477692 1.000 rs516704 chr10:131419879 G/A cg19680672 chr10:131412579 MGMT -0.44 -6.86 -0.35 3.33e-11 Response to temozolomide; LIHC cis rs7707921 0.723 rs73138787 chr5:81568934 G/A cg15871215 chr5:81402204 ATG10 -0.7 -8.2 -0.41 5.06e-15 Breast cancer; LIHC trans rs1814175 0.817 rs12295885 chr11:50036762 T/G cg03929089 chr4:120376271 NA -0.89 -18.71 -0.71 2.82e-54 Height; LIHC cis rs4746818 1.000 rs7071904 chr10:70903005 C/T cg11621586 chr10:70884670 VPS26A 0.87 14.21 0.61 2.47e-36 Left atrial antero-posterior diameter; LIHC cis rs919433 0.617 rs700646 chr2:198608511 C/T cg10820045 chr2:198174542 NA 0.49 7.44 0.37 8.27e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11031096 0.738 rs2923950 chr11:4042069 G/C cg18678763 chr11:4115507 RRM1 0.42 6.26 0.32 1.18e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10883723 0.810 rs12265877 chr10:104247247 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.08 0.58 5.66e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4713118 0.662 rs149969 chr6:27977737 A/G cg16479474 chr6:28041457 NA 0.42 6.6 0.34 1.61e-10 Parkinson's disease; LIHC cis rs2836974 0.563 rs997147 chr21:40695325 A/G cg11890956 chr21:40555474 PSMG1 -0.47 -7.46 -0.37 7.27e-13 Cognitive function; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg12435611 chr17:59941052 BRIP1 -0.43 -6.27 -0.32 1.09e-9 Bipolar disorder; LIHC trans rs7618501 0.521 rs2883059 chr3:49902160 C/T cg21659725 chr3:3221576 CRBN -0.57 -8.32 -0.41 2.11e-15 Intelligence (multi-trait analysis); LIHC trans rs10506458 1.000 rs10506458 chr12:63445092 G/A cg22491629 chr6:157744540 C6orf35 -0.58 -10.11 -0.48 3.34e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs12464559 0.649 rs4233654 chr2:152596011 C/G cg01189475 chr2:152685088 ARL5A -0.63 -7.4 -0.37 1.04e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs9649213 0.593 rs6947340 chr7:97912241 A/G cg08684580 chr7:98029266 BAIAP2L1 0.38 5.82 0.3 1.38e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs782590 0.934 rs62165184 chr2:55788253 G/C cg03859395 chr2:55845619 SMEK2 0.85 15.1 0.63 7.58e-40 Metabolic syndrome; LIHC cis rs17102423 0.964 rs868814 chr14:65584508 C/T cg11161011 chr14:65562177 MAX -0.46 -6.29 -0.32 9.85e-10 Obesity-related traits; LIHC cis rs600806 0.888 rs461200 chr1:109855404 G/A cg16275483 chr1:110013120 SYPL2 -0.51 -6.26 -0.32 1.14e-9 Intelligence (multi-trait analysis); LIHC cis rs9635726 0.638 rs2952155 chr17:37861718 T/C cg00129232 chr17:37814104 STARD3 -0.45 -7.86 -0.39 5.07e-14 Primary biliary cholangitis; LIHC cis rs6450176 0.633 rs389525 chr5:53333075 G/C ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.5 -0.59 1.4e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg02951883 chr7:2050386 MAD1L1 -0.76 -13.15 -0.58 3.05e-32 Bipolar disorder and schizophrenia; LIHC cis rs17376456 0.825 rs1470150 chr5:93138654 C/T cg25358565 chr5:93447407 FAM172A -1.01 -9.58 -0.46 2.13e-19 Diabetic retinopathy; LIHC cis rs74544699 1.000 rs11574452 chr4:74846661 A/C cg15398841 chr4:74847761 PF4 -0.59 -6.08 -0.31 3.22e-9 Growth-regulated protein alpha levels; LIHC cis rs2952156 0.920 rs2247862 chr17:37829129 A/G cg00129232 chr17:37814104 STARD3 -0.5 -9.3 -0.45 1.72e-18 Asthma; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02892961 chr21:34863959 DNAJC28 -0.5 -6.08 -0.31 3.16e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg21724239 chr8:58056113 NA 0.49 6.28 0.32 1.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs4689592 0.503 rs2292461 chr4:7058473 C/T cg26116260 chr4:7069785 GRPEL1 0.89 15.37 0.64 6.58e-41 Monocyte percentage of white cells; LIHC cis rs10792665 0.640 rs10898055 chr11:82628257 G/C cg24227371 chr11:82718527 RAB30 -0.27 -6.25 -0.32 1.26e-9 Obesity-related traits; LIHC cis rs11098499 0.722 rs10006192 chr4:120263022 T/C cg09307838 chr4:120376055 NA 0.63 9.82 0.47 3.21e-20 Corneal astigmatism; LIHC cis rs7107174 1.000 rs2450123 chr11:77952771 T/C cg02023728 chr11:77925099 USP35 0.49 9.3 0.45 1.68e-18 Testicular germ cell tumor; LIHC cis rs4665809 0.941 rs11126336 chr2:26245931 C/T cg27170947 chr2:26402098 FAM59B -0.68 -8.49 -0.42 6.52e-16 Gut microbiome composition (summer); LIHC cis rs7762018 0.607 rs79897010 chr6:170042874 C/G cg19338460 chr6:170058176 WDR27 -0.9 -9.03 -0.44 1.28e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs72960926 0.744 rs77045321 chr6:74915572 T/C cg07247405 chr1:2484626 LOC115110 0.52 6.04 0.31 4.09e-9 Metabolite levels (MHPG); LIHC cis rs4789452 0.538 rs2627207 chr17:75353160 A/G cg05865280 chr17:75406074 SEPT9 -0.33 -6.75 -0.34 6.48e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs9814567 1.000 rs7611611 chr3:134307877 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7208859 0.524 rs77498725 chr17:29063986 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7258465 0.965 rs271628 chr19:18624333 A/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.32 -0.37 1.76e-12 Breast cancer; LIHC cis rs2075371 0.965 rs1862049 chr7:133978344 A/T cg11752832 chr7:134001865 SLC35B4 0.49 7.42 0.37 9.12e-13 Mean platelet volume; LIHC cis rs4820294 1.000 rs4820294 chr22:38071043 G/A cg26138144 chr22:38071188 LGALS1 0.75 14.09 0.61 7.25e-36 Fat distribution (HIV); LIHC cis rs6545883 0.899 rs12473030 chr2:61720497 T/A cg15711740 chr2:61764176 XPO1 -0.43 -5.94 -0.31 7.2e-9 Tuberculosis; LIHC cis rs6121246 0.697 rs7269866 chr20:30232504 G/A cg13852791 chr20:30311386 BCL2L1 0.82 8.24 0.41 3.62e-15 Mean corpuscular hemoglobin; LIHC cis rs868943 0.582 rs12209373 chr6:116488925 G/A cg08036074 chr6:116424633 NT5DC1 -0.61 -6.6 -0.34 1.57e-10 Total cholesterol levels; LIHC cis rs611744 0.967 rs660065 chr8:109191932 G/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg11494091 chr17:61959527 GH2 0.45 8.15 0.4 6.72e-15 Prudent dietary pattern; LIHC cis rs17401966 0.867 rs10492973 chr1:10398985 T/C cg15208524 chr1:10270712 KIF1B 0.38 5.79 0.3 1.62e-8 Hepatocellular carcinoma; LIHC cis rs59698941 0.765 rs67045943 chr5:132219956 C/T cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs2952156 0.920 rs907090 chr17:37833632 T/C cg00129232 chr17:37814104 STARD3 -0.53 -10.23 -0.48 1.35e-21 Asthma; LIHC cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg18305652 chr10:134549665 INPP5A 0.44 6.47 0.33 3.38e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs800082 0.839 rs17282884 chr3:144319905 C/T cg24215973 chr2:240111563 HDAC4 0.49 6.87 0.35 2.99e-11 Smoking behavior; LIHC cis rs7659604 0.840 rs6821305 chr4:122713863 A/C cg19748678 chr4:122722346 EXOSC9 0.49 8.07 0.4 1.21e-14 Type 2 diabetes; LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg04267008 chr7:1944627 MAD1L1 -0.64 -10.15 -0.48 2.46e-21 Bipolar disorder and schizophrenia; LIHC cis rs7616330 0.836 rs73118214 chr3:71047396 A/C cg01511742 chr3:71112437 FOXP1 -0.45 -6.05 -0.31 3.78e-9 QT interval; LIHC cis rs11758351 0.660 rs11759904 chr6:26231443 T/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs10911251 0.546 rs1547715 chr1:183113952 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 3.82e-23 Colorectal cancer; LIHC cis rs4843747 0.697 rs72818533 chr16:88073841 G/A cg06050784 chr16:88016603 BANP 0.39 6.76 0.34 5.95e-11 Menopause (age at onset); LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs1712517 0.771 rs11191654 chr10:105077124 C/A cg05636881 chr10:105038444 INA 0.48 7.58 0.38 3.19e-13 Migraine; LIHC cis rs941408 0.515 rs1005556 chr19:2778543 G/T cg06609049 chr19:2785107 THOP1 0.77 12.84 0.57 4.59e-31 Total cholesterol levels; LIHC cis rs1215050 0.904 rs165246 chr4:98688541 C/T cg05340658 chr4:99064831 C4orf37 0.42 5.84 0.3 1.22e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg06601766 chr17:61851465 DDX42;CCDC47 -0.61 -9.57 -0.46 2.27e-19 Height; LIHC cis rs7772486 0.720 rs9403757 chr6:146261271 C/T cg13319975 chr6:146136371 FBXO30 0.35 5.72 0.3 2.27e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs12101261 0.580 rs4411444 chr14:81445108 A/G cg06600135 chr14:81408086 NA 0.44 7.74 0.39 1.11e-13 Graves' disease; LIHC cis rs9303401 0.659 rs34913878 chr17:56897094 A/G cg25039879 chr17:56429692 SUPT4H1 0.77 8.91 0.43 3e-17 Cognitive test performance; LIHC cis rs1577917 0.958 rs6454487 chr6:86446868 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.42 7.9 0.39 3.91e-14 Response to antipsychotic treatment; LIHC cis rs9790314 0.967 rs457272 chr3:161096746 A/G cg03342759 chr3:160939853 NMD3 -0.69 -8.14 -0.4 7.27e-15 Morning vs. evening chronotype; LIHC cis rs7551222 0.752 rs4951398 chr1:204531876 T/C cg20240347 chr1:204465584 NA -0.35 -7.53 -0.38 4.64e-13 Schizophrenia; LIHC cis rs921968 0.678 rs2230115 chr2:219509618 C/A cg02985541 chr2:219472218 PLCD4 0.43 7.8 0.39 7.5e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs7677751 0.806 rs1800810 chr4:55094031 C/G cg17187183 chr4:55093834 PDGFRA 0.68 8.52 0.42 5.06e-16 Corneal astigmatism; LIHC cis rs61776719 0.500 rs11210866 chr1:38449565 T/C cg12658694 chr1:38397304 INPP5B 0.52 7.73 0.39 1.23e-13 Coronary artery disease; LIHC cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.85 0.54 2.32e-27 Colorectal cancer; LIHC cis rs7412746 0.611 rs10888391 chr1:150729983 G/A cg18016565 chr1:150552671 MCL1 0.56 10.79 0.5 1.48e-23 Melanoma; LIHC cis rs875971 0.545 rs10950027 chr7:65634151 C/T cg11764359 chr7:65958608 NA 0.51 7.0 0.35 1.34e-11 Aortic root size; LIHC cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg00684032 chr4:1343700 KIAA1530 -0.38 -6.18 -0.32 1.78e-9 Obesity-related traits; LIHC cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg10862848 chr6:42927986 GNMT -0.28 -6.37 -0.33 6.01e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs477692 0.905 rs485579 chr10:131425492 T/G cg19680672 chr10:131412579 MGMT -0.42 -6.5 -0.33 2.89e-10 Response to temozolomide; LIHC cis rs6912958 0.703 rs12207825 chr6:88098292 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.56 10.41 0.49 3.03e-22 Monocyte percentage of white cells; LIHC cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.45 -6.07 -0.31 3.46e-9 Bipolar disorder; LIHC cis rs7914558 0.646 rs10883799 chr10:104663310 G/A cg15744005 chr10:104629667 AS3MT -0.34 -7.09 -0.36 7.9e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs722599 0.501 rs2286914 chr14:75387012 T/C cg08847533 chr14:75593920 NEK9 -0.6 -10.28 -0.49 8.81e-22 IgG glycosylation; LIHC cis rs2153535 0.580 rs9379222 chr6:8514788 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.77 0.54 4.4e-27 Motion sickness; LIHC cis rs7208859 0.623 rs170051 chr17:28914153 G/A cg14067834 chr17:29058358 SUZ12P 0.67 6.6 0.34 1.53e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg12310025 chr6:25882481 NA -0.5 -6.09 -0.31 2.96e-9 Intelligence (multi-trait analysis); LIHC cis rs7249142 0.562 rs10854009 chr19:19284705 A/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.43 -7.11 -0.36 6.74e-12 IgG glycosylation; LIHC cis rs1799949 0.602 rs8176257 chr17:41216205 G/T cg10360323 chr17:41437877 NA 0.41 5.96 0.31 6.2e-9 Menopause (age at onset); LIHC cis rs60871478 1.000 rs9195 chr7:825786 C/T cg04727924 chr7:799746 HEATR2 0.57 8.74 0.43 1.06e-16 Cerebrospinal P-tau181p levels; LIHC cis rs2952156 1.000 rs4252627 chr17:37868715 C/T cg00129232 chr17:37814104 STARD3 -0.5 -9.15 -0.44 5.08e-18 Asthma; LIHC cis rs7106204 0.514 rs34587986 chr11:24253053 T/C ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.24e-27 Response to Homoharringtonine (cytotoxicity); LIHC cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.86 0.3 1.12e-8 Aortic root size; LIHC trans rs17685 0.735 rs11763339 chr7:75761541 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7903847 0.642 rs3814553 chr10:99155984 G/A cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6502050 0.799 rs8069827 chr17:80089168 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC trans rs1656966 1.000 rs1656966 chr3:186466252 C/T cg22857957 chr1:146697082 FMO5 -0.38 -6.2 -0.32 1.63e-9 Myopia (pathological); LIHC trans rs800082 0.802 rs2717380 chr3:144256908 A/T cg24215973 chr2:240111563 HDAC4 0.44 6.26 0.32 1.15e-9 Smoking behavior; LIHC cis rs3741404 0.609 rs666497 chr11:63869821 G/C cg05016508 chr11:63871570 FLRT1;MACROD1 0.41 6.58 0.34 1.78e-10 Platelet count; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17789012 chr17:13972896 COX10 -0.54 -6.18 -0.32 1.87e-9 Systolic blood pressure; LIHC cis rs9952991 0.882 rs2847274 chr18:12777603 T/C cg23598886 chr18:12777645 NA 0.48 6.48 0.33 3.13e-10 Inflammatory skin disease; LIHC trans rs4824093 0.610 rs56810176 chr22:50303149 G/C cg09872104 chr7:134855509 C7orf49 -0.76 -6.14 -0.32 2.25e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs10504229 0.610 rs7011877 chr8:58147181 C/T cg11062466 chr8:58055876 NA 0.42 6.12 0.31 2.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg07424592 chr7:64974309 NA 0.82 9.58 0.46 2.09e-19 Diabetic kidney disease; LIHC cis rs36051895 0.530 rs7036833 chr9:5226484 G/A cg02405213 chr9:5042618 JAK2 -0.61 -9.19 -0.45 3.91e-18 Pediatric autoimmune diseases; LIHC cis rs743757 1.000 rs762897 chr3:50428766 C/A cg08207895 chr3:50388901 TUSC4;CYB561D2 0.42 6.27 0.32 1.12e-9 Diastolic blood pressure; LIHC cis rs66573146 1.000 rs6838042 chr4:6973049 G/T cg15105060 chr4:7024189 TBC1D14 -0.72 -6.07 -0.31 3.44e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs55665837 0.701 rs10766188 chr11:14660826 T/C cg19336497 chr11:14380999 RRAS2 -0.36 -6.03 -0.31 4.26e-9 Vitamin D levels; LIHC cis rs1046896 0.561 rs8076476 chr17:80861017 A/C cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.42 0.33 4.62e-10 Glycated hemoglobin levels; LIHC cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg08280861 chr8:58055591 NA 0.55 6.12 0.31 2.59e-9 Developmental language disorder (linguistic errors); LIHC cis rs1144333 0.655 rs1417402 chr1:76437196 C/T cg22875332 chr1:76189707 ACADM 0.43 6.27 0.32 1.1e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs9309473 1.000 rs11674602 chr2:73723185 A/T cg20560298 chr2:73613845 ALMS1 -0.58 -6.91 -0.35 2.38e-11 Metabolite levels; LIHC cis rs3784262 0.904 rs17820823 chr15:58239358 A/G cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.2 -0.32 1.6e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs911555 0.504 rs8006526 chr14:104075015 T/C cg24130564 chr14:104152367 KLC1 -0.65 -12.19 -0.55 1.24e-28 Intelligence (multi-trait analysis); LIHC cis rs637571 0.522 rs493899 chr11:65747952 A/C cg02202077 chr11:65769826 EIF1AD;BANF1 0.4 6.04 0.31 3.94e-9 Eosinophil percentage of white cells; LIHC cis rs6952808 0.630 rs1860832 chr7:2161849 G/A cg20295408 chr7:1910781 MAD1L1 -0.41 -5.99 -0.31 5.3300000000000004e-09 Bipolar disorder and schizophrenia; LIHC cis rs9457247 1.000 rs439237 chr6:167391392 A/G cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs7937890 0.593 rs2597189 chr11:14512060 C/T cg02886208 chr11:14281011 SPON1 -0.49 -6.61 -0.34 1.46e-10 Mitochondrial DNA levels; LIHC cis rs7552404 1.000 rs12091720 chr1:76186949 G/A cg10523679 chr1:76189770 ACADM 0.64 8.98 0.44 1.89e-17 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg11792281 chr17:26443366 NLK 0.6 6.33 0.32 7.58e-10 Mean platelet volume; LIHC cis rs10870270 0.913 rs4880326 chr10:133745547 C/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.74 -0.57 1.07e-30 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs12478296 1.000 rs7420157 chr2:243005204 G/A cg18898632 chr2:242989856 NA -0.47 -6.5 -0.33 2.86e-10 Obesity-related traits; LIHC trans rs916888 0.779 rs199528 chr17:44843136 C/T cg07870213 chr5:140052090 DND1 1.02 10.14 0.48 2.72e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg22508957 chr16:3507546 NAT15 0.48 8.34 0.41 1.88e-15 Tuberculosis; LIHC cis rs870825 0.929 rs1405940 chr4:185591481 A/G cg04058563 chr4:185651563 MLF1IP 0.72 6.2 0.32 1.59e-9 Blood protein levels; LIHC cis rs796364 0.950 rs188146 chr2:200750444 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.77 8.92 0.43 2.83e-17 Schizophrenia; LIHC cis rs66569888 0.789 rs1317569 chr2:106735490 C/A cg23109721 chr2:106886537 NA -0.65 -6.29 -0.32 9.47e-10 Facial morphology (factor 23); LIHC cis rs875971 0.540 rs736270 chr7:65428822 T/C cg11764359 chr7:65958608 NA 0.7 9.53 0.46 2.95e-19 Aortic root size; LIHC cis rs4727027 0.933 rs6464940 chr7:148826309 G/T cg23583168 chr7:148888333 NA -0.73 -9.99 -0.48 8.47e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2303745 0.589 rs7246262 chr19:17392483 C/G cg04248312 chr19:17393744 ANKLE1 -0.73 -12.08 -0.55 3.08e-28 Systemic lupus erythematosus; LIHC cis rs597539 0.690 rs608810 chr11:68624118 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.71 9.73 0.47 6.31e-20 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9814567 1.000 rs2370578 chr3:134199612 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.7 -12.43 -0.56 1.53e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg21724239 chr8:58056113 NA 0.56 7.18 0.36 4.37e-12 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.595 rs3778984 chr7:2166514 T/C cg04267008 chr7:1944627 MAD1L1 -0.53 -8.23 -0.41 3.97e-15 Bipolar disorder and schizophrenia; LIHC cis rs35110281 0.667 rs4819288 chr21:45120173 C/G cg21573476 chr21:45109991 RRP1B -0.57 -11.0 -0.51 2.67e-24 Mean corpuscular volume; LIHC cis rs35160687 0.623 rs2276625 chr2:86481835 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.37 -6.13 -0.31 2.36e-9 Night sleep phenotypes; LIHC cis rs2180341 1.000 rs6569478 chr6:127598619 G/A cg24812749 chr6:127587940 RNF146 1.05 15.71 0.65 2.87e-42 Breast cancer; LIHC cis rs2070488 0.775 rs2268762 chr3:38516075 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.53 0.56 6.83e-30 Electrocardiographic conduction measures; LIHC cis rs9649213 0.574 rs36099592 chr7:98002331 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.24e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs11724903 0.935 rs11732877 chr4:183206596 A/G cg16239906 chr20:35724590 RBL1 -0.62 -6.15 -0.32 2.21e-9 Smoking initiation; LIHC cis rs2439831 0.850 rs28564774 chr15:44125475 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.73 0.34 7.11e-11 Lung cancer in ever smokers; LIHC cis rs763121 0.925 rs4821797 chr22:39016182 T/C cg14440974 chr22:39074834 NA -0.36 -6.06 -0.31 3.56e-9 Menopause (age at onset); LIHC cis rs12477438 0.520 rs2516827 chr2:99772565 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.24 0.61 1.91e-36 Chronic sinus infection; LIHC cis rs79057730 0.639 rs6463933 chr7:793954 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.88 9.96 0.47 1.14e-20 Initial pursuit acceleration; LIHC cis rs74233809 1.000 rs10883835 chr10:104884208 T/C cg03493300 chr10:104813866 CNNM2 0.47 6.34 0.32 7.15e-10 Birth weight; LIHC cis rs7777484 0.534 rs2533886 chr7:2834869 C/T cg18446336 chr7:2847575 GNA12 -0.33 -6.58 -0.34 1.77e-10 Height; LIHC cis rs875971 0.638 rs10249404 chr7:66046724 G/A cg14393609 chr7:65229607 NA -0.38 -6.04 -0.31 4.07e-9 Aortic root size; LIHC cis rs11025559 0.812 rs16906280 chr11:20472242 T/C cg19653624 chr11:20408972 PRMT3 -0.49 -6.32 -0.32 7.97e-10 Pursuit maintenance gain; LIHC cis rs9814567 1.000 rs13087875 chr3:134261123 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg19635926 chr16:89946313 TCF25 0.55 7.39 0.37 1.11e-12 Skin colour saturation; LIHC cis rs10193935 0.901 rs222488 chr2:42648570 T/G cg27598129 chr2:42591480 NA -0.69 -10.31 -0.49 6.91e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs2439831 1.000 rs689647 chr15:43762196 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.83 0.43 5.6e-17 Lung cancer in ever smokers; LIHC cis rs1008375 0.931 rs10008337 chr4:17593849 G/C cg02297831 chr4:17616191 MED28 0.46 7.1 0.36 7.4e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs67311347 0.866 rs9826419 chr3:40352051 G/A cg13409248 chr3:40428643 ENTPD3 0.38 5.9 0.3 8.59e-9 Renal cell carcinoma; LIHC cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 9.74 0.47 6.04e-20 Platelet count; LIHC cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg23758822 chr17:41437982 NA 0.94 17.82 0.69 1.05e-50 Menopause (age at onset); LIHC cis rs4901869 0.966 rs12878614 chr14:59339477 A/C cg02291164 chr14:59296302 NA 0.44 5.86 0.3 1.09e-8 Panic disorder; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg20273358 chr20:56100118 CTCFL 0.48 6.34 0.32 7.36e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1371867 0.846 rs1788205 chr8:101306546 G/C cg06636551 chr8:101224915 SPAG1 -0.5 -9.06 -0.44 1.02e-17 Atrioventricular conduction; LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg12419862 chr22:24373484 LOC391322 -0.7 -10.21 -0.48 1.49e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7312933 0.528 rs10880238 chr12:42489613 A/G cg01256987 chr12:42539512 GXYLT1 -0.65 -12.3 -0.55 4.98e-29 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs8141529 0.732 rs5762815 chr22:29205076 A/G cg02153584 chr22:29168773 CCDC117 0.58 9.42 0.45 7.06e-19 Lymphocyte counts; LIHC cis rs12908161 0.959 rs61074241 chr15:85333396 C/T cg17507749 chr15:85114479 UBE2QP1 0.62 6.61 0.34 1.52e-10 Schizophrenia; LIHC cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.55 7.75 0.39 1.08e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs6754311 0.731 rs10207652 chr2:136588478 T/A cg17750252 chr2:136567154 LCT 0.33 5.93 0.31 7.44e-9 Mosquito bite size; LIHC cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg19774624 chr17:42201019 HDAC5 0.78 11.94 0.54 1.08e-27 Total body bone mineral density; LIHC cis rs9902453 0.709 rs6505162 chr17:28444183 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.28 0.52 2.73e-25 Coffee consumption (cups per day); LIHC cis rs3096299 0.967 rs16965692 chr16:89471482 C/T cg00750074 chr16:89608354 SPG7 -0.38 -5.79 -0.3 1.59e-8 Multiple myeloma (IgH translocation); LIHC cis rs3099143 0.901 rs1611866 chr15:77236291 A/C cg21673338 chr15:77095150 SCAPER -0.5 -6.83 -0.35 3.86e-11 Recalcitrant atopic dermatitis; LIHC cis rs782590 0.837 rs782584 chr2:55921116 C/G cg18811423 chr2:55921094 PNPT1 -1.03 -17.48 -0.69 2.42e-49 Metabolic syndrome; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC trans rs9929218 1.000 rs12443730 chr16:68804342 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.78 -0.43 8.25e-17 Colorectal cancer; LIHC cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg24879335 chr3:133465180 TF 0.29 6.46 0.33 3.56e-10 Iron status biomarkers; LIHC cis rs2276314 1.000 rs4799834 chr18:33566243 T/C cg05985134 chr18:33552581 C18orf21 0.48 5.72 0.3 2.34e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs2153535 0.541 rs1414353 chr6:8485642 C/G cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC trans rs61931739 0.517 rs11053224 chr12:34484919 G/A cg26384229 chr12:38710491 ALG10B 0.8 10.15 0.48 2.5e-21 Morning vs. evening chronotype; LIHC cis rs722599 0.683 rs10144845 chr14:75237770 C/T cg11812906 chr14:75593930 NEK9 0.4 6.06 0.31 3.67e-9 IgG glycosylation; LIHC cis rs34779708 0.931 rs12242882 chr10:35347860 G/C cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.41e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg17554472 chr22:41940697 POLR3H 0.56 6.04 0.31 3.98e-9 Vitiligo; LIHC cis rs597539 0.652 rs496616 chr11:68672800 G/C cg04772025 chr11:68637568 NA 0.45 5.91 0.3 8.31e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9381040 0.610 rs4140580 chr6:41041742 C/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.37 -5.86 -0.3 1.08e-8 Alzheimer's disease (late onset); LIHC cis rs8017423 0.935 rs12880102 chr14:90793526 G/T cg04374321 chr14:90722782 PSMC1 -0.73 -13.26 -0.58 1.2e-32 Mortality in heart failure; LIHC cis rs11055034 0.560 rs2024385 chr12:12888438 A/T cg04607235 chr12:12878440 APOLD1 0.68 11.44 0.53 6.89e-26 Birth weight; LIHC cis rs12477438 0.798 rs7570657 chr2:99654281 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.61 -0.5 6.32e-23 Chronic sinus infection; LIHC trans rs867371 0.820 rs12443224 chr15:82495610 C/T cg18393722 chr15:85113863 UBE2QP1 -0.46 -7.98 -0.4 2.31e-14 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs6089584 0.830 rs4925331 chr20:60580174 T/C cg12751644 chr20:60527061 NA -0.37 -6.14 -0.32 2.31e-9 Body mass index; LIHC cis rs1401999 0.864 rs4148563 chr3:183725999 T/C cg01324343 chr3:183735012 ABCC5 0.76 12.53 0.56 6.59e-30 Anterior chamber depth; LIHC cis rs6669384 0.774 rs4844623 chr1:208035434 T/A cg22525895 chr1:207977042 MIR29B2 -0.53 -5.84 -0.3 1.21e-8 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs6782228 0.606 rs2001703 chr3:128383097 A/G cg16766828 chr3:128327626 NA -0.4 -6.39 -0.33 5.54e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg00684032 chr4:1343700 KIAA1530 0.5 7.63 0.38 2.36e-13 Obesity-related traits; LIHC cis rs3809863 0.646 rs9899121 chr17:45395144 C/T cg08085267 chr17:45401833 C17orf57 -0.63 -9.84 -0.47 2.77e-20 Glaucoma (primary open-angle); LIHC cis rs7551222 0.752 rs12130686 chr1:204554057 G/C cg20240347 chr1:204465584 NA -0.31 -6.28 -0.32 1.01e-9 Schizophrenia; LIHC trans rs2243480 0.901 rs13237344 chr7:66022256 T/A cg10756647 chr7:56101905 PSPH 1.02 12.11 0.55 2.53e-28 Diabetic kidney disease; LIHC cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg09913183 chr17:42254507 C17orf65;ASB16 -0.81 -12.39 -0.56 2.25e-29 Total body bone mineral density; LIHC cis rs10791097 0.694 rs61910787 chr11:130744473 G/A cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9814567 0.752 rs1534030 chr3:134330083 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4927850 0.881 rs7624638 chr3:195748729 C/T cg12923728 chr3:195709715 SDHAP1 -0.74 -10.58 -0.5 8.1e-23 Pancreatic cancer; LIHC trans rs2243480 0.522 rs12698511 chr7:65474919 G/T cg10756647 chr7:56101905 PSPH 1.15 13.01 0.58 1.02e-31 Diabetic kidney disease; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.27 0.55 6.38e-29 Prudent dietary pattern; LIHC cis rs74181299 0.684 rs6756585 chr2:65340070 G/A cg05010058 chr2:65284262 CEP68 -0.41 -6.89 -0.35 2.63e-11 Pulse pressure; LIHC cis rs7520050 0.807 rs72688483 chr1:46149209 A/G cg24296786 chr1:45957014 TESK2 -0.39 -5.76 -0.3 1.92e-8 Red blood cell count;Reticulocyte count; LIHC cis rs9522267 0.535 rs9522301 chr13:112236726 A/T cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs5769765 0.646 rs9616205 chr22:50309915 A/T cg02269571 chr22:50332266 NA -0.65 -8.83 -0.43 5.68e-17 Schizophrenia; LIHC cis rs7116495 0.609 rs2845860 chr11:71716661 C/T cg26138937 chr11:71823887 C11orf51 -1.32 -10.9 -0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs2070488 0.636 rs2284817 chr3:38510388 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.58 8.14 0.4 7.35e-15 Electrocardiographic conduction measures; LIHC cis rs1801251 1.000 rs6761324 chr2:233582793 T/G cg25237894 chr2:233734115 C2orf82 0.57 11.14 0.52 8.65e-25 Coronary artery disease; LIHC cis rs4561483 0.798 rs33629 chr16:11997490 G/A cg08843971 chr16:11963173 GSPT1 -0.35 -6.98 -0.35 1.52e-11 Testicular germ cell tumor; LIHC cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg16680214 chr1:154839983 KCNN3 -0.35 -5.95 -0.31 6.64e-9 Prostate cancer; LIHC cis rs6120849 0.707 rs3746448 chr20:33572979 C/T cg24642439 chr20:33292090 TP53INP2 0.66 7.33 0.37 1.64e-12 Protein C levels; LIHC cis rs1348850 0.526 rs6433672 chr2:178378175 G/T cg27490568 chr2:178487706 NA 0.95 10.46 0.49 2.07e-22 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg04944784 chr2:26401820 FAM59B 0.72 9.21 0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs6429082 0.783 rs291364 chr1:235687179 A/G cg26050004 chr1:235667680 B3GALNT2 0.48 7.76 0.39 1.01e-13 Adiposity; LIHC cis rs9393777 0.588 rs6941920 chr6:26492149 C/T cg12826209 chr6:26865740 GUSBL1 0.68 8.14 0.4 7.54e-15 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.781 rs7761814 chr6:88188309 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.11 -0.36 6.88e-12 Monocyte percentage of white cells; LIHC cis rs1639906 0.893 rs13233298 chr7:2227707 C/T cg22963979 chr7:1858916 MAD1L1 -0.4 -5.94 -0.31 6.99e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00975115 chr16:30958403 FBXL19 0.45 6.45 0.33 3.8e-10 Longevity; LIHC cis rs36051895 0.664 rs3780372 chr9:5097544 C/T cg02405213 chr9:5042618 JAK2 -0.69 -11.91 -0.54 1.39e-27 Pediatric autoimmune diseases; LIHC cis rs35306767 0.761 rs12359796 chr10:1021479 G/C cg26597838 chr10:835615 NA 0.9 8.19 0.41 5.11e-15 Eosinophil percentage of granulocytes; LIHC cis rs59698941 0.943 rs60545802 chr5:132204577 T/G cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg00656387 chr3:40428638 ENTPD3 0.43 7.18 0.36 4.51e-12 Renal cell carcinoma; LIHC cis rs4268898 0.679 rs2543666 chr2:24446042 C/T cg06627628 chr2:24431161 ITSN2 0.65 8.87 0.43 4.17e-17 Asthma; LIHC cis rs34540877 1.000 rs34377680 chr19:33121874 C/A cg22980127 chr19:33182716 NUDT19 1.01 6.75 0.34 6.37e-11 Red cell distribution width; LIHC cis rs11098499 0.754 rs12711071 chr4:120240934 A/G cg09307838 chr4:120376055 NA 0.71 10.9 0.51 6.27e-24 Corneal astigmatism; LIHC cis rs10751667 0.643 rs6597970 chr11:928669 C/A cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg11764359 chr7:65958608 NA 0.57 6.09 0.31 3.09e-9 Diabetic kidney disease; LIHC cis rs6062302 0.548 rs4809310 chr20:62228745 G/A cg09650180 chr20:62225654 GMEB2 -0.39 -6.01 -0.31 4.72e-9 Glioblastoma; LIHC cis rs28595532 0.623 rs10016452 chr4:119277490 A/G cg21605333 chr4:119757512 SEC24D 0.82 6.81 0.35 4.28e-11 Cannabis dependence symptom count; LIHC cis rs7520050 0.966 rs6700597 chr1:46284246 G/A cg03146154 chr1:46216737 IPP -0.4 -6.55 -0.33 2.11e-10 Red blood cell count;Reticulocyte count; LIHC cis rs6570726 0.791 rs4335004 chr6:145904764 G/A cg13319975 chr6:146136371 FBXO30 -0.41 -6.53 -0.33 2.45e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs909002 0.789 rs3817398 chr1:32119431 C/T cg13919466 chr1:32135498 COL16A1 0.34 6.39 0.33 5.38e-10 Intelligence (multi-trait analysis); LIHC cis rs600806 0.850 rs10776807 chr1:109956156 A/G cg23091122 chr1:110024289 SYPL2 0.45 6.14 0.31 2.32e-9 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg10360323 chr17:41437877 NA 0.39 5.84 0.3 1.24e-8 Menopause (age at onset); LIHC cis rs5758511 0.514 rs5758586 chr22:42517471 A/T cg00645731 chr22:42541494 CYP2D7P1 0.52 8.34 0.41 1.84e-15 Birth weight; LIHC cis rs2304069 1.000 rs2304069 chr5:149406733 G/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.94 12.11 0.55 2.55e-28 HIV-1 control; LIHC cis rs4927850 1.000 rs7627706 chr3:195753353 A/C cg12923728 chr3:195709715 SDHAP1 -0.74 -10.61 -0.5 6.46e-23 Pancreatic cancer; LIHC cis rs57221529 0.766 rs56216231 chr5:581193 G/A cg09021430 chr5:549028 NA -0.45 -8.73 -0.43 1.14e-16 Lung disease severity in cystic fibrosis; LIHC cis rs568617 0.768 rs12225345 chr11:65647105 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.55 7.72 0.39 1.33e-13 Crohn's disease; LIHC cis rs589448 0.872 rs315111 chr12:69784695 G/A cg19645103 chr12:69753606 YEATS4 -0.4 -6.07 -0.31 3.49e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs763121 0.853 rs9610986 chr22:39025277 T/C cg06022373 chr22:39101656 GTPBP1 0.66 11.55 0.53 2.74e-26 Menopause (age at onset); LIHC trans rs2018683 0.624 rs6462119 chr7:29003725 G/C cg19402173 chr7:128379420 CALU -0.38 -6.04 -0.31 4.02e-9 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg06466757 chr4:1255808 NA 0.34 5.8 0.3 1.53e-8 Obesity-related traits; LIHC cis rs67460515 0.596 rs4856700 chr3:160922951 A/C cg17135325 chr3:160939158 NMD3 0.59 8.47 0.42 7.36e-16 Parkinson's disease; LIHC trans rs208515 0.525 rs12215007 chr6:66671008 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -9.03 -0.44 1.26e-17 Exhaled nitric oxide levels; LIHC trans rs11098499 0.863 rs10018280 chr4:120478139 T/G cg25214090 chr10:38739885 LOC399744 0.57 8.97 0.44 2.03e-17 Corneal astigmatism; LIHC cis rs17384381 0.953 rs2284797 chr1:85792383 C/T cg16011679 chr1:85725395 C1orf52 0.84 9.03 0.44 1.26e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs9309473 1.000 rs6736866 chr2:73661986 C/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.68 -0.34 9.95e-11 Metabolite levels; LIHC cis rs2292096 0.850 rs6663728 chr1:200815179 G/T cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -5.96 -0.31 6.35e-9 Epilepsy; LIHC cis rs796364 1.000 rs281788 chr2:200783705 A/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.7 8.35 0.41 1.67e-15 Schizophrenia; LIHC cis rs4925386 0.959 rs4925385 chr20:60920624 A/G cg03945807 chr20:60948434 NA -0.36 -6.47 -0.33 3.37e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg07424592 chr7:64974309 NA 0.79 9.12 0.44 6.72e-18 Diabetic kidney disease; LIHC trans rs801193 0.660 rs10950049 chr7:66230860 T/C cg10756647 chr7:56101905 PSPH 0.47 6.95 0.35 1.86e-11 Aortic root size; LIHC cis rs9902453 0.619 rs1038088 chr17:28074563 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -12.72 -0.57 1.27e-30 Coffee consumption (cups per day); LIHC cis rs1144333 0.655 rs1146649 chr1:76268803 A/G cg10523679 chr1:76189770 ACADM -0.45 -6.16 -0.32 2.06e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2180341 0.883 rs9388568 chr6:127690694 C/A cg24812749 chr6:127587940 RNF146 1.03 15.33 0.64 9.68e-41 Breast cancer; LIHC cis rs74233809 1.000 rs77180047 chr10:104666757 G/A cg03493300 chr10:104813866 CNNM2 0.46 6.02 0.31 4.57e-9 Birth weight; LIHC cis rs999943 0.846 rs1570760 chr6:33622933 C/T cg14003231 chr6:33640908 ITPR3 0.38 7.73 0.39 1.21e-13 Obesity (extreme); LIHC cis rs9811920 0.638 rs793503 chr3:99588070 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.81 0.3 1.43e-8 Axial length; LIHC cis rs1865760 0.964 rs9295677 chr6:25933712 T/C cg03264133 chr6:25882463 NA -0.4 -6.01 -0.31 4.72e-9 Height; LIHC trans rs983392 0.709 rs4939320 chr11:59981801 T/C cg17275991 chr19:58003312 ZNF419 0.43 6.16 0.32 2.09e-9 Alzheimer's disease (late onset); LIHC cis rs17094222 0.812 rs10786600 chr10:102435521 A/G cg26540559 chr10:102447443 NA 0.32 6.14 0.32 2.24e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs16858210 0.520 rs35586421 chr3:183544607 G/A cg25686905 chr3:183603175 PARL -0.44 -7.22 -0.36 3.31e-12 Menopause (age at onset); LIHC cis rs35146811 0.660 rs6465760 chr7:99591418 A/G cg22906224 chr7:99728672 NA -0.46 -6.27 -0.32 1.11e-9 Coronary artery disease; LIHC cis rs1865721 0.804 rs35653478 chr18:73212546 C/T cg26385618 chr18:73139727 C18orf62 -0.29 -7.38 -0.37 1.18e-12 Intelligence; LIHC trans rs526821 0.595 rs629948 chr11:55356448 G/A cg03929089 chr4:120376271 NA -0.45 -6.87 -0.35 3.14e-11 Pediatric bone mineral density (spine); LIHC cis rs6942756 1.000 rs9640854 chr7:128884057 A/T cg02491457 chr7:128862824 NA -0.72 -11.25 -0.52 3.43e-25 White matter hyperintensity burden; LIHC trans rs1814175 0.791 rs10769593 chr11:49616217 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -22.74 -0.78 2.13e-70 Height; LIHC cis rs9368481 0.761 rs3931464 chr6:26939856 C/A cg18867708 chr6:26865862 GUSBL1 0.54 8.09 0.4 1.05e-14 Autism spectrum disorder or schizophrenia; LIHC cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg04944784 chr2:26401820 FAM59B -0.71 -9.07 -0.44 9.29e-18 Gut microbiome composition (summer); LIHC cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.13 -0.44 6.13e-18 Bipolar disorder; LIHC cis rs7618501 1.000 rs7649348 chr3:49772375 G/A cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.893 rs2281735 chr20:60582540 T/A cg23262073 chr20:60523788 NA -0.28 -5.77 -0.3 1.74e-8 Body mass index; LIHC cis rs2286503 0.839 rs4722189 chr7:22860474 G/A cg11367502 chr7:22862612 TOMM7 0.45 7.58 0.38 3.22e-13 Fibrinogen; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.36 0.45 1.08e-18 Height; LIHC cis rs6456156 0.583 rs7748224 chr6:167456860 C/T cg23791538 chr6:167370224 RNASET2 -0.53 -8.47 -0.42 7.38e-16 Primary biliary cholangitis; LIHC cis rs67981189 0.593 rs1558097 chr14:71557267 T/A cg15816911 chr14:71606274 NA 0.43 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs11098499 0.909 rs10014719 chr4:120320715 G/A cg09307838 chr4:120376055 NA 0.76 11.85 0.54 2.28e-27 Corneal astigmatism; LIHC cis rs4820539 0.966 rs5996470 chr22:23483255 G/A cg21100191 chr22:23484243 RTDR1 0.95 18.28 0.7 1.51e-52 Bone mineral density; LIHC cis rs9303280 0.806 rs9909593 chr17:37970149 C/T cg00129232 chr17:37814104 STARD3 0.36 5.96 0.31 6.44e-9 Self-reported allergy; LIHC cis rs72627123 0.500 rs68148895 chr14:74529523 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.49 6.72 0.34 7.7e-11 Morning vs. evening chronotype; LIHC cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg20295408 chr7:1910781 MAD1L1 -0.48 -6.99 -0.35 1.46e-11 Bipolar disorder and schizophrenia; LIHC cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg00612595 chr21:47717864 NA -0.35 -5.78 -0.3 1.71e-8 Testicular germ cell tumor; LIHC cis rs4638749 0.677 rs7370742 chr2:108815385 T/C cg06795125 chr2:108905320 SULT1C2 -0.31 -6.04 -0.31 3.92e-9 Blood pressure; LIHC cis rs7772486 0.754 rs12199362 chr6:146118225 A/G cg23711669 chr6:146136114 FBXO30 0.75 13.72 0.6 1.93e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs1555399 0.934 rs10133618 chr14:67981403 G/C cg16224230 chr14:67978224 TMEM229B -0.24 -5.82 -0.3 1.37e-8 Parkinson's disease; LIHC cis rs6088813 1.000 rs1406947 chr20:33969530 C/T cg14752227 chr20:34000481 UQCC -0.4 -5.79 -0.3 1.61e-8 Height; LIHC cis rs13343954 0.518 rs8106293 chr19:33536376 C/T cg17764715 chr19:33622953 WDR88 0.52 7.35 0.37 1.46e-12 Colorectal cancer; LIHC cis rs1577917 1.000 rs12215903 chr6:86675028 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.94 -0.47 1.29e-20 Response to antipsychotic treatment; LIHC cis rs7267979 0.932 rs6037125 chr20:25463382 G/A cg24626310 chr20:25276739 ABHD12;PYGB 0.47 6.88 0.35 2.8e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs1997103 1.000 rs2009441 chr7:55405989 A/G cg17469321 chr7:55412551 NA 0.48 7.09 0.36 7.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7095944 0.614 rs4962697 chr10:126447545 G/C cg20435097 chr10:126320824 FAM53B 0.38 6.3 0.32 9.36e-10 Asthma; LIHC cis rs7223966 0.961 rs17631783 chr17:61687600 A/G cg05941027 chr17:61774174 LIMD2 -0.32 -6.3 -0.32 9.18e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs8180040 0.620 rs6768722 chr3:47079112 G/A cg16586182 chr3:47516702 SCAP -0.47 -8.57 -0.42 3.7e-16 Colorectal cancer; LIHC cis rs3859192 0.599 rs2227321 chr17:38171294 G/C cg17467752 chr17:38218738 THRA -0.51 -8.64 -0.42 2.19e-16 White blood cell count; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08264122 chr7:1882997 MAD1L1 0.4 6.04 0.31 4.01e-9 Longevity; LIHC cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg18357526 chr6:26021779 HIST1H4A -0.88 -12.36 -0.56 3.02e-29 Intelligence (multi-trait analysis); LIHC cis rs7647973 0.593 rs7620848 chr3:49828021 G/C cg03060546 chr3:49711283 APEH -0.59 -6.86 -0.35 3.28e-11 Menarche (age at onset); LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs67478160 0.595 rs12889993 chr14:104274294 A/G cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.48 -0.37 6.33e-13 Schizophrenia; LIHC cis rs244293 0.965 rs244310 chr17:53212655 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC trans rs6934970 1.000 rs28623201 chr6:113083939 G/C cg19071452 chr2:152146944 NMI -0.57 -6.08 -0.31 3.21e-9 Bipolar disorder (body mass index interaction); LIHC cis rs1552244 0.882 rs55808392 chr3:10054681 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.53 -0.49 1.17e-22 Alzheimer's disease; LIHC cis rs2439831 1.000 rs2584725 chr15:43793135 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.64 9.01 0.44 1.47e-17 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03442064 chr6:41515050 FOXP4 0.47 7.12 0.36 6.56e-12 Pancreatic cancer; LIHC cis rs1707322 1.000 rs10890375 chr1:46406581 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.85e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs722599 0.748 rs61978948 chr14:75363369 G/A cg11812906 chr14:75593930 NEK9 -0.45 -7.13 -0.36 5.85e-12 IgG glycosylation; LIHC cis rs1448094 0.527 rs59445394 chr12:86237843 C/T cg02569458 chr12:86230093 RASSF9 0.5 6.57 0.33 1.88e-10 Major depressive disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22276571 chr20:17549599 DSTN 0.39 6.44 0.33 4.02e-10 Cognitive function; LIHC cis rs7187994 0.848 rs16974560 chr16:84788425 A/G cg07647771 chr16:84786436 USP10 -0.31 -6.02 -0.31 4.44e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs13108904 0.846 rs12643212 chr4:1224948 A/G cg05665937 chr4:1216051 CTBP1 0.47 6.42 0.33 4.57e-10 Obesity-related traits; LIHC cis rs8062405 0.728 rs11642449 chr16:28896015 C/T cg00204512 chr16:28754710 NA 0.34 6.1 0.31 2.79e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg13012494 chr21:47604986 C21orf56 -0.38 -5.86 -0.3 1.08e-8 Testicular germ cell tumor; LIHC trans rs11039798 0.623 rs594615 chr11:48402804 T/C cg15704280 chr7:45808275 SEPT13 -0.57 -6.32 -0.32 8.05e-10 Axial length; LIHC cis rs597539 0.617 rs686348 chr11:68636996 A/G cg06028808 chr11:68637592 NA 0.43 5.84 0.3 1.21e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg15691649 chr6:25882328 NA -0.39 -6.14 -0.32 2.23e-9 Height; LIHC cis rs7412746 0.658 rs4970986 chr1:150907955 A/G cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs7659604 0.540 rs10001092 chr4:122677177 C/T cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.51e-11 Type 2 diabetes; LIHC cis rs7786877 0.521 rs4729606 chr7:100321790 T/C cg20848291 chr7:100343083 ZAN -0.49 -7.05 -0.36 9.68e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7937890 0.532 rs2575827 chr11:14475515 A/G cg02886208 chr11:14281011 SPON1 -0.46 -6.58 -0.34 1.75e-10 Mitochondrial DNA levels; LIHC cis rs1387259 0.931 rs11168474 chr12:48621384 A/C cg21466736 chr12:48725269 NA -0.7 -10.73 -0.5 2.33e-23 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs1008375 1.000 rs3815414 chr4:17606659 A/G cg15017067 chr4:17643749 FAM184B -0.34 -5.72 -0.3 2.34e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17106184 1.000 rs72902736 chr1:51239976 A/G cg07174182 chr1:51127561 FAF1 -0.61 -6.65 -0.34 1.18e-10 Type 2 diabetes; LIHC cis rs9733 0.596 rs1136808 chr1:150702717 G/C cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs796364 1.000 rs4410273 chr2:200818258 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.7 8.32 0.41 2.08e-15 Schizophrenia; LIHC cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg22764044 chr5:178986830 RUFY1 -0.4 -5.92 -0.3 8.03e-9 Lung cancer; LIHC cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.6 -0.38 2.81e-13 Bipolar disorder; LIHC cis rs1003719 0.751 rs2835585 chr21:38460488 T/A cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.28 0.55 6.02e-29 Eye color traits; LIHC cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg06634786 chr22:41940651 POLR3H -0.78 -8.67 -0.42 1.76e-16 Vitiligo; LIHC cis rs9640161 0.711 rs3800781 chr7:150027324 T/A cg10018233 chr7:150070692 REPIN1 0.51 7.96 0.4 2.48e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs765787 0.530 rs11634794 chr15:45534492 A/C cg24006582 chr15:45444508 DUOX1 -0.53 -7.7 -0.38 1.5e-13 Uric acid levels; LIHC cis rs3936840 0.647 rs942024 chr14:102979463 C/T cg10241871 chr14:102965420 TECPR2 -0.41 -6.04 -0.31 4.05e-9 Plateletcrit; LIHC cis rs4665809 1.000 rs4233709 chr2:26291493 C/T cg27170947 chr2:26402098 FAM59B 0.6 7.45 0.37 7.73e-13 Gut microbiome composition (summer); LIHC cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg02290350 chr8:58132656 NA 0.42 7.96 0.4 2.6e-14 Developmental language disorder (linguistic errors); LIHC cis rs4934494 0.911 rs7081788 chr10:91408756 G/A cg19698084 chr10:91461284 KIF20B -0.45 -6.15 -0.32 2.19e-9 Red blood cell count; LIHC cis rs11792861 0.926 rs12683988 chr9:111867290 T/C cg13535736 chr9:111863775 C9orf5 -0.38 -5.73 -0.3 2.21e-8 Menarche (age at onset); LIHC cis rs611744 0.901 rs2348801 chr8:109167337 C/T cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.14e-10 Dupuytren's disease; LIHC cis rs12477438 0.798 rs9308816 chr2:99637230 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.67 -0.5 3.78e-23 Chronic sinus infection; LIHC cis rs4665809 1.000 rs4665816 chr2:26305094 G/C cg27170947 chr2:26402098 FAM59B -0.61 -7.73 -0.39 1.22e-13 Gut microbiome composition (summer); LIHC cis rs9916302 0.861 rs11078912 chr17:37671490 A/G cg00129232 chr17:37814104 STARD3 -0.4 -6.51 -0.33 2.67e-10 Glomerular filtration rate (creatinine); LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg00800038 chr16:89945340 TCF25 -0.67 -10.53 -0.49 1.16e-22 Skin colour saturation; LIHC cis rs1401999 0.628 rs6798870 chr3:183740350 G/A cg01324343 chr3:183735012 ABCC5 0.62 9.95 0.47 1.19e-20 Anterior chamber depth; LIHC cis rs9393777 0.588 rs4518487 chr6:26467531 A/G cg12826209 chr6:26865740 GUSBL1 0.65 7.85 0.39 5.23e-14 Intelligence (multi-trait analysis); LIHC cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg21664854 chr7:1097933 C7orf50;GPR146 0.8 6.29 0.32 9.85e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg20295408 chr7:1910781 MAD1L1 -0.46 -6.74 -0.34 6.81e-11 Bipolar disorder and schizophrenia; LIHC cis rs2836950 0.565 rs2150414 chr21:40614988 A/G cg17971929 chr21:40555470 PSMG1 -0.39 -5.84 -0.3 1.18e-8 Menarche (age at onset); LIHC cis rs3859192 0.557 rs12602514 chr17:38159745 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.89 0.65 5.82e-43 White blood cell count; LIHC cis rs7592578 0.882 rs61117285 chr2:191468986 G/C cg10560079 chr2:191398806 TMEM194B -0.87 -12.24 -0.55 8.17e-29 Diastolic blood pressure; LIHC cis rs12971120 0.947 rs7241558 chr18:72169267 A/T cg25817165 chr18:72167213 CNDP2 -0.68 -12.72 -0.57 1.24e-30 Refractive error; LIHC cis rs240764 0.631 rs12195369 chr6:101204106 G/A cg09795085 chr6:101329169 ASCC3 -0.54 -7.62 -0.38 2.5e-13 Neuroticism; LIHC cis rs916888 0.773 rs199533 chr17:44828931 G/A cg01570182 chr17:44337453 NA 0.99 9.86 0.47 2.35e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs644799 0.603 rs1255180 chr11:95472134 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.62 10.19 0.48 1.85e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7666738 0.716 rs13136721 chr4:99085602 G/A cg05340658 chr4:99064831 C4orf37 0.69 12.24 0.55 8.46e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs40363 0.645 rs250630 chr16:3524242 C/T cg22508957 chr16:3507546 NAT15 0.49 8.78 0.43 7.98e-17 Tuberculosis; LIHC cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg03264133 chr6:25882463 NA -0.55 -8.14 -0.4 7.36e-15 Blood metabolite levels; LIHC cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg15556689 chr8:8085844 FLJ10661 -0.42 -6.95 -0.35 1.85e-11 Neuroticism; LIHC cis rs2842992 0.915 rs1322427 chr6:160075454 C/A cg26839252 chr6:160211577 TCP1;MRPL18 0.35 5.79 0.3 1.61e-8 Age-related macular degeneration (geographic atrophy); LIHC cis rs10857712 0.851 rs7913420 chr10:135213854 C/T cg19623624 chr10:135278901 LOC619207 -0.41 -6.33 -0.32 7.59e-10 Systemic lupus erythematosus; LIHC cis rs2857078 0.654 rs9896789 chr17:42314567 C/T cg19774624 chr17:42201019 HDAC5 -0.45 -6.32 -0.32 8.12e-10 Red cell distribution width;Reticulocyte count; LIHC cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg21486233 chr12:29375141 FAR2 0.31 5.94 0.31 6.9e-9 QT interval; LIHC cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.95e-9 Menopause (age at onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg10038085 chr1:165797905 UCK2 -0.42 -6.4 -0.33 5.18e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25916527 chr5:72292534 FCHO2 0.51 8.01 0.4 1.78e-14 Bilirubin levels; LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg22528358 chr1:107598549 PRMT6 0.72 11.91 0.54 1.35e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3820068 0.637 rs4646080 chr1:15826627 A/T cg17385448 chr1:15911702 AGMAT 0.37 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs2816062 0.813 rs2816051 chr1:18895460 A/G cg18795169 chr1:18902165 NA -0.8 -18.23 -0.7 2.41e-52 Urate levels in lean individuals; LIHC cis rs9303401 0.921 rs34102441 chr17:56877414 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.42 6.3 0.32 9.13e-10 Cognitive test performance; LIHC cis rs9486719 0.948 rs2499813 chr6:96875338 T/C cg06623918 chr6:96969491 KIAA0776 0.73 7.14 0.36 5.7e-12 Migraine;Coronary artery disease; LIHC cis rs8060686 0.545 rs78229587 chr16:68165243 T/C cg09835421 chr16:68378352 PRMT7 -0.55 -6.26 -0.32 1.16e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs3749237 1.000 rs3749237 chr3:49770032 C/T cg21659725 chr3:3221576 CRBN 0.78 12.24 0.55 8.09e-29 Resting heart rate; LIHC cis rs12765878 0.967 rs34887477 chr10:105643436 C/T cg11005552 chr10:105648138 OBFC1 0.39 6.15 0.32 2.2e-9 Coronary artery disease; LIHC cis rs7937682 1.000 rs11608149 chr11:111535102 G/A cg09085632 chr11:111637200 PPP2R1B 1.1 13.42 0.59 2.83e-33 Primary sclerosing cholangitis; LIHC cis rs9902453 0.817 rs55974138 chr17:28215546 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.03e-27 Coffee consumption (cups per day); LIHC cis rs1949733 1.000 rs2140337 chr4:8502112 A/G cg11789530 chr4:8429930 ACOX3 0.79 11.85 0.54 2.27e-27 Response to antineoplastic agents; LIHC cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg03264133 chr6:25882463 NA -0.5 -6.17 -0.32 1.93e-9 Intelligence (multi-trait analysis); LIHC cis rs7248779 0.512 rs12610522 chr19:2413228 C/T cg22729335 chr19:2427816 TIMM13 1.11 24.65 0.8 8.07e-78 Cortisol levels (saliva); LIHC cis rs2832191 0.716 rs1543652 chr21:30448000 G/C cg08807101 chr21:30365312 RNF160 0.78 11.71 0.54 7.24e-27 Dental caries; LIHC cis rs564343 0.560 rs11227384 chr11:65799332 G/T cg08986711 chr11:66045560 CNIH2 0.37 5.71 0.3 2.42e-8 Obesity (early onset extreme); LIHC cis rs7927592 0.913 rs12363722 chr11:68236291 A/C cg16797656 chr11:68205561 LRP5 0.54 8.61 0.42 2.63e-16 Total body bone mineral density; LIHC cis rs72634258 0.503 rs34177663 chr1:7833228 A/G cg00864860 chr1:7907996 UTS2 0.6 5.93 0.31 7.29e-9 Inflammatory bowel disease; LIHC cis rs7598759 0.527 rs7571691 chr2:232369401 C/T cg19187155 chr2:232395269 NMUR1 0.54 8.38 0.41 1.41e-15 Noise-induced hearing loss; LIHC cis rs4654899 1.000 rs4654896 chr1:21356930 T/C cg08539965 chr1:21396338 EIF4G3 0.34 5.93 0.31 7.37e-9 Superior frontal gyrus grey matter volume; LIHC cis rs694739 0.628 rs475032 chr11:64140737 G/C cg02228329 chr11:64053129 BAD;GPR137 -0.56 -7.7 -0.38 1.45e-13 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg20887711 chr4:1340912 KIAA1530 0.78 12.29 0.55 5.45e-29 Longevity; LIHC cis rs10419226 0.625 rs12974777 chr19:18765663 C/T cg14292368 chr19:18793705 CRTC1 -0.54 -9.1 -0.44 7.8e-18 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC trans rs877282 0.853 rs7092652 chr10:756109 G/A cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs34779708 0.931 rs11010130 chr10:35513307 T/C cg04310649 chr10:35416472 CREM -0.43 -5.71 -0.3 2.41e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17685 0.753 rs6953665 chr7:75769049 C/T cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9420 0.961 rs80304923 chr11:57522823 C/G cg19752551 chr11:57585705 CTNND1 -0.52 -7.34 -0.37 1.56e-12 Schizophrenia; LIHC trans rs10506458 0.915 rs12423078 chr12:63397529 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.73 -10.37 -0.49 4.5e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs523522 0.926 rs10849766 chr12:121025894 G/A cg27279351 chr12:120934652 DYNLL1 0.67 11.93 0.54 1.11e-27 High light scatter reticulocyte count; LIHC cis rs10089 1.000 rs4836367 chr5:127482592 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.74 0.34 6.56e-11 Ileal carcinoids; LIHC cis rs7909074 1.000 rs1408814 chr10:45399088 A/G cg04218760 chr10:45406644 TMEM72 -0.23 -7.3 -0.37 2.09e-12 Mean corpuscular volume; LIHC cis rs7312933 0.584 rs6582395 chr12:42700141 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.85 0.39 5.36e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs12887734 0.524 rs12888002 chr14:104238647 T/C cg01849466 chr14:104193079 ZFYVE21 -0.41 -6.22 -0.32 1.46e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs1814175 0.645 rs7952104 chr11:49964180 C/T cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs2243480 1.000 rs958550 chr7:65635679 C/T cg12463550 chr7:65579703 CRCP -0.6 -6.32 -0.32 8.39e-10 Diabetic kidney disease; LIHC trans rs783540 0.500 rs783541 chr15:83255061 T/C cg18393722 chr15:85113863 UBE2QP1 -0.45 -6.76 -0.34 5.83e-11 Schizophrenia; LIHC cis rs11711311 0.824 rs35952547 chr3:113352501 G/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.37 -6.47 -0.33 3.37e-10 IgG glycosylation; LIHC cis rs7959452 0.684 rs11177615 chr12:69754189 G/A cg20891283 chr12:69753455 YEATS4 0.9 19.29 0.72 1.23e-56 Blood protein levels; LIHC cis rs1552244 0.882 rs9812006 chr3:10022658 T/C cg08888203 chr3:10149979 C3orf24 0.44 5.73 0.3 2.16e-8 Alzheimer's disease; LIHC cis rs67478160 0.619 rs12878682 chr14:104233627 G/C cg08213375 chr14:104286397 PPP1R13B 0.66 13.06 0.58 6.68e-32 Schizophrenia; LIHC trans rs877282 0.945 rs71489301 chr10:770191 A/G cg22713356 chr15:30763199 NA 1.25 11.04 0.51 2e-24 Uric acid levels; LIHC cis rs11888559 0.655 rs4675315 chr2:204018529 C/T cg24605529 chr2:203879461 NBEAL1 0.78 5.92 0.31 7.62e-9 Height; LIHC cis rs1801251 1.000 rs35085837 chr2:233624363 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.21 0.52 4.87e-25 Coronary artery disease; LIHC cis rs6952808 0.500 rs3778996 chr7:2177190 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.83 -0.3 1.3e-8 Bipolar disorder and schizophrenia; LIHC cis rs12464559 0.649 rs3922996 chr2:152609668 A/G cg01189475 chr2:152685088 ARL5A 0.61 7.19 0.36 4.22e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7188697 0.882 rs37054 chr16:58558989 C/T cg02549819 chr16:58548995 SETD6 -0.46 -7.21 -0.36 3.65e-12 QT interval; LIHC cis rs2204008 0.685 rs4556621 chr12:38187236 C/A cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs317689 0.513 rs529268 chr12:69687051 G/A cg14784868 chr12:69753453 YEATS4 0.66 10.69 0.5 3.41e-23 Response to diuretic therapy; LIHC cis rs1401999 0.510 rs3749438 chr3:183705184 G/A cg01324343 chr3:183735012 ABCC5 0.41 6.55 0.33 2.14e-10 Anterior chamber depth; LIHC cis rs6882046 0.513 rs34320 chr5:88021527 T/G cg22951263 chr5:87985283 NA -0.38 -6.5 -0.33 2.84e-10 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs7617480 0.617 rs7610519 chr3:48746427 C/G cg07636037 chr3:49044803 WDR6 0.71 8.28 0.41 2.86e-15 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs11098499 0.954 rs6849171 chr4:120409549 G/A cg09307838 chr4:120376055 NA 0.78 12.71 0.57 1.43e-30 Corneal astigmatism; LIHC cis rs8078723 0.668 rs56030650 chr17:38131187 C/A cg17344932 chr17:38183730 MED24;SNORD124 -0.6 -10.05 -0.48 5.52e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2439831 1.000 rs2253708 chr15:43797273 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 13.85 0.6 6.27e-35 Lung cancer in ever smokers; LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs13394619 1.000 rs2884374 chr2:11731846 C/T cg07314298 chr2:11723111 GREB1 0.48 9.22 0.45 3.06e-18 Endometriosis; LIHC cis rs6684514 1.000 rs12045339 chr1:156294211 C/T cg16558208 chr1:156270281 VHLL 0.54 10.19 0.48 1.83e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9583531 0.509 rs12184676 chr13:111396484 A/G cg24331049 chr13:111365604 ING1 -0.75 -9.95 -0.47 1.19e-20 Coronary artery disease; LIHC cis rs11628318 0.614 rs12588817 chr14:103089210 G/A cg23461800 chr14:103021989 NA -0.39 -5.9 -0.3 8.95e-9 Platelet count; LIHC cis rs9902453 0.817 rs1842026 chr17:28188111 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.33 0.55 3.71e-29 Coffee consumption (cups per day); LIHC cis rs35110281 0.592 rs6417729 chr21:44967202 A/C cg04455712 chr21:45112962 RRP1B 0.42 7.0 0.35 1.33e-11 Mean corpuscular volume; LIHC cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg00166722 chr3:10149974 C3orf24 0.52 6.02 0.31 4.54e-9 Alzheimer's disease; LIHC cis rs9828933 0.577 rs832194 chr3:63857071 G/A cg16258503 chr3:63850278 ATXN7;THOC7 0.84 11.13 0.52 8.99e-25 Type 2 diabetes; LIHC cis rs12893668 0.703 rs7148456 chr14:104028270 C/T cg24130564 chr14:104152367 KLC1 0.56 9.78 0.47 4.45e-20 Reticulocyte count; LIHC cis rs66573146 0.656 rs41410847 chr4:6957332 C/T cg00086871 chr4:6988644 TBC1D14 0.73 5.95 0.31 6.78e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs72781680 0.898 rs72798041 chr2:23953076 T/C cg08917208 chr2:24149416 ATAD2B 0.96 8.19 0.41 5.08e-15 Lymphocyte counts; LIHC cis rs7098414 0.511 rs10887828 chr10:82151470 T/C cg01528321 chr10:82214614 TSPAN14 0.43 6.51 0.33 2.67e-10 Post bronchodilator FEV1; LIHC cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 9.64 0.46 1.34e-19 Platelet count; LIHC cis rs12451471 0.559 rs1042396 chr17:78084769 G/A cg24585782 chr17:78113791 EIF4A3 -0.43 -5.75 -0.3 1.95e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs7552404 1.000 rs1498316 chr1:76159198 G/A cg22875332 chr1:76189707 ACADM 0.46 6.65 0.34 1.16e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs17401966 0.838 rs4529713 chr1:10307295 A/G cg19773385 chr1:10388646 KIF1B -0.39 -7.16 -0.36 5.02e-12 Hepatocellular carcinoma; LIHC cis rs10857712 1.000 rs10857712 chr10:135225666 T/C cg19904058 chr10:135279010 LOC619207 -0.35 -5.71 -0.3 2.46e-8 Systemic lupus erythematosus; LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg18279126 chr7:2041391 MAD1L1 -0.37 -6.08 -0.31 3.19e-9 Bipolar disorder and schizophrenia; LIHC trans rs11039798 0.582 rs60764175 chr11:48775856 T/G cg15704280 chr7:45808275 SEPT13 0.61 6.99 0.35 1.44e-11 Axial length; LIHC cis rs9427116 0.502 rs3766922 chr1:154577055 A/C cg17218026 chr1:154582156 ADAR 0.33 6.56 0.33 1.94e-10 Blood protein levels; LIHC cis rs9560113 0.509 rs28608633 chr13:112206880 G/A cg10483660 chr13:112241077 NA 0.25 6.17 0.32 1.96e-9 Menarche (age at onset); LIHC cis rs703842 0.616 rs4760332 chr12:58222672 A/C cg18357645 chr12:58087776 OS9 0.42 6.12 0.31 2.62e-9 Multiple sclerosis; LIHC trans rs3820928 0.605 rs13410141 chr2:227805529 A/G cg16088116 chr21:44841560 SIK1 -0.4 -6.21 -0.32 1.54e-9 Pulmonary function; LIHC cis rs4642101 0.765 rs6791647 chr3:12826425 C/T cg24848339 chr3:12840334 CAND2 -0.29 -5.9 -0.3 8.69e-9 QRS complex (12-leadsum); LIHC cis rs459571 0.959 rs2520100 chr9:136918137 A/T cg13789015 chr9:136890014 NCRNA00094 0.45 8.28 0.41 2.83e-15 Platelet distribution width; LIHC cis rs11608355 0.515 rs12833054 chr12:109890955 G/A cg05360138 chr12:110035743 NA 0.95 10.45 0.49 2.37e-22 Neuroticism; LIHC cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg26119090 chr2:26468346 HADHA;HADHB -1.14 -17.92 -0.7 4.26e-51 Gut microbiome composition (summer); LIHC cis rs2361718 0.603 rs12951255 chr17:78085597 A/G cg09238746 chr17:78121135 EIF4A3 -0.49 -6.87 -0.35 3.01e-11 Yeast infection; LIHC cis rs4474465 1.000 rs7927722 chr11:78210893 T/C cg27205649 chr11:78285834 NARS2 0.43 6.35 0.32 6.85e-10 Alzheimer's disease (survival time); LIHC cis rs7582720 1.000 rs72936870 chr2:203789679 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs250677 0.687 rs40522 chr5:148442295 G/A cg18129178 chr5:148520854 ABLIM3 -0.48 -7.48 -0.38 6.18e-13 Breast cancer; LIHC cis rs679087 1.000 rs679087 chr12:29917265 C/A cg14258853 chr12:29935411 TMTC1 -0.5 -7.82 -0.39 6.65e-14 Schizophrenia; LIHC cis rs7129220 0.858 rs61878630 chr11:10132815 A/T cg01453529 chr11:10209919 SBF2 -0.38 -6.88 -0.35 2.92e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC trans rs2739330 0.828 rs2877178 chr22:24251517 C/T cg06437703 chr8:37914619 EIF4EBP1 -0.48 -7.25 -0.36 2.79e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs738321 0.671 rs3761446 chr22:38595483 G/A cg25457927 chr22:38595422 NA -0.4 -9.3 -0.45 1.73e-18 Breast cancer; LIHC cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg10295955 chr4:187884368 NA 0.93 21.3 0.76 1.1e-64 Lobe attachment (rater-scored or self-reported); LIHC cis rs12893668 0.616 rs58033365 chr14:104030901 T/C cg19000871 chr14:103996768 TRMT61A -0.43 -7.05 -0.36 9.88e-12 Reticulocyte count; LIHC cis rs6693567 0.826 rs1260387 chr1:150371448 T/C cg18016565 chr1:150552671 MCL1 -0.37 -6.11 -0.31 2.66e-9 Migraine; LIHC cis rs2576037 0.526 rs7240239 chr18:44460037 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 10.53 0.49 1.2e-22 Personality dimensions; LIHC cis rs13161895 1.000 rs34882290 chr5:179463836 C/A cg06664874 chr5:179499304 RNF130 0.58 7.08 0.36 8.06e-12 LDL cholesterol; LIHC cis rs909341 0.818 rs2259858 chr20:62346459 A/T cg03999872 chr20:62272968 STMN3 -0.45 -6.8 -0.35 4.72e-11 Atopic dermatitis; LIHC cis rs7712401 0.686 rs246305 chr5:122199606 A/T cg18764291 chr5:122110994 SNX2 0.33 5.82 0.3 1.37e-8 Mean platelet volume; LIHC cis rs7208859 0.623 rs77009951 chr17:29080650 T/C cg14067834 chr17:29058358 SUZ12P 0.68 6.71 0.34 8.11e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67981189 0.593 rs221925 chr14:71579629 T/G cg15816911 chr14:71606274 NA -0.42 -6.75 -0.34 6.31e-11 Schizophrenia; LIHC cis rs12908161 1.000 rs58416181 chr15:85264461 G/A cg17507749 chr15:85114479 UBE2QP1 0.66 7.54 0.38 4.21e-13 Schizophrenia; LIHC cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.75 0.3 2.01e-8 Schizophrenia; LIHC cis rs1957429 0.803 rs10873177 chr14:65318228 G/C cg23373153 chr14:65346875 NA 0.78 11.15 0.52 7.64e-25 Pediatric areal bone mineral density (radius); LIHC trans rs208520 0.661 rs704519 chr6:66801136 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.13 -0.44 5.97e-18 Exhaled nitric oxide output; LIHC trans rs1814175 0.647 rs28456013 chr11:50047629 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -12.72 -0.57 1.27e-30 Height; LIHC trans rs911555 0.723 rs12894652 chr14:103926024 A/G cg17675199 chr6:35436792 RPL10A -0.45 -9.17 -0.44 4.52e-18 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.629 rs13081028 chr3:52555316 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.19 0.36 4.08e-12 Electroencephalogram traits; LIHC cis rs986417 0.901 rs10134736 chr14:60998540 A/T cg27398547 chr14:60952738 C14orf39 0.72 7.9 0.39 3.82e-14 Gut microbiota (bacterial taxa); LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.24 0.81 4.27e-80 Prudent dietary pattern; LIHC cis rs965469 0.779 rs6037546 chr20:3298697 G/T cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC trans rs10411161 0.702 rs10420224 chr19:52398955 A/G cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs12477438 0.798 rs7570657 chr2:99654281 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.78e-13 Chronic sinus infection; LIHC cis rs425535 0.588 rs6810940 chr4:74842189 A/G cg02530824 chr4:74847766 PF4 0.37 6.07 0.31 3.46e-9 Blood protein levels; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.75 0.8 3.17e-78 Prudent dietary pattern; LIHC cis rs8067354 0.645 rs28516945 chr17:57816578 T/C cg02344993 chr17:57696989 CLTC 0.7 11.74 0.54 5.5e-27 Hemoglobin concentration; LIHC cis rs651907 0.557 rs2318090 chr3:101474933 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.49 -6.88 -0.35 2.84e-11 Colorectal cancer; LIHC cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg08888203 chr3:10149979 C3orf24 0.59 6.57 0.33 1.92e-10 Alzheimer's disease; LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.64 9.44 0.45 6.15e-19 Lymphocyte counts; LIHC cis rs7131987 0.903 rs7308125 chr12:29425211 T/C cg05697976 chr12:29376483 FAR2 0.31 6.3 0.32 9.28e-10 QT interval; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02438054 chr19:4791315 FEM1A -0.58 -6.78 -0.34 5.14e-11 Systolic blood pressure; LIHC cis rs7674212 0.570 rs2126470 chr4:104061762 T/C cg16532752 chr4:104119610 CENPE -0.45 -7.01 -0.35 1.29e-11 Type 2 diabetes; LIHC cis rs72717009 0.756 rs10494359 chr1:161463876 G/C cg23840854 chr1:161414152 NA -0.59 -6.0 -0.31 5.1e-9 Rheumatoid arthritis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05391628 chr12:49463937 RHEBL1 0.44 6.5 0.33 2.83e-10 Cognitive function; LIHC cis rs1419980 0.730 rs12229540 chr12:7776578 A/C cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC cis rs17401966 0.964 rs2027331 chr1:10276718 C/T cg19773385 chr1:10388646 KIF1B -0.47 -8.03 -0.4 1.58e-14 Hepatocellular carcinoma; LIHC cis rs6754311 0.731 rs7569057 chr2:136583958 A/C cg07305463 chr2:136567211 LCT -0.38 -7.24 -0.36 2.99e-12 Mosquito bite size; LIHC trans rs1814175 0.935 rs7925863 chr11:49615802 C/A cg03929089 chr4:120376271 NA -0.88 -17.01 -0.68 1.81e-47 Height; LIHC cis rs10791097 0.720 rs6590516 chr11:130733393 G/T cg09137382 chr11:130731461 NA 0.39 5.85 0.3 1.16e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs561341 1.000 rs535151 chr17:30317405 C/T cg13647721 chr17:30228624 UTP6 0.69 6.72 0.34 7.39e-11 Hip circumference adjusted for BMI; LIHC cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg10360139 chr7:1886902 MAD1L1 -0.4 -6.17 -0.32 1.89e-9 Bipolar disorder and schizophrenia; LIHC cis rs7552404 0.655 rs1146646 chr1:76265500 G/A cg22875332 chr1:76189707 ACADM 0.42 5.94 0.31 7.11e-9 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs67460515 0.852 rs2404341 chr3:161092405 T/C cg03342759 chr3:160939853 NMD3 -0.57 -8.44 -0.42 8.96e-16 Parkinson's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04309227 chr1:26561027 CCDC21 0.5 7.14 0.36 5.55e-12 Pancreatic cancer; LIHC cis rs11295209 1 rs11295209 chr4:120480233 TA/T cg09307838 chr4:120376055 NA -0.47 -6.95 -0.35 1.86e-11 Plateletcrit; LIHC cis rs8072100 0.840 rs12453233 chr17:45454570 C/T cg08085267 chr17:45401833 C17orf57 -0.55 -8.28 -0.41 2.73e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs5769765 0.955 rs9616367 chr22:50303515 A/C cg02269571 chr22:50332266 NA -0.74 -9.77 -0.47 4.64e-20 Schizophrenia; LIHC cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.98 0.44 1.78e-17 Platelet count; LIHC cis rs4908760 0.827 rs11121210 chr1:8708529 T/C cg20416874 chr1:8611966 RERE -0.64 -12.78 -0.57 7.53e-31 Vitiligo; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25632300 chr5:174905618 SFXN1 0.59 7.71 0.38 1.4e-13 Lung function (FEV1/FVC); LIHC cis rs11958404 0.929 rs72816533 chr5:157413352 G/T cg05962755 chr5:157440814 NA 0.96 10.52 0.49 1.28e-22 IgG glycosylation; LIHC cis rs7919006 1.000 rs6480766 chr10:76803880 G/A cg01390419 chr10:76803856 DUPD1 0.5 7.82 0.39 6.68e-14 Weight; LIHC cis rs9916302 0.904 rs9944411 chr17:37483599 T/C cg03013999 chr17:37608204 MED1 -0.35 -5.82 -0.3 1.38e-8 Glomerular filtration rate (creatinine); LIHC cis rs7208859 0.673 rs999797 chr17:29159329 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.02 0.4 1.66e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7917772 0.560 rs3862030 chr10:104327584 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.17e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs950776 0.518 rs11632604 chr15:78821914 T/C cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.21 0.36 3.69e-12 Height; LIHC cis rs9467773 1.000 rs9467778 chr6:26534743 T/C cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02634712 chr18:19750909 GATA6 0.45 6.06 0.31 3.67e-9 Pancreatic cancer; LIHC cis rs10979 1.000 rs9484769 chr6:143896719 A/G cg25407410 chr6:143891975 LOC285740 -0.36 -5.72 -0.3 2.33e-8 Hypospadias; LIHC cis rs12464559 0.579 rs2293221 chr2:152653380 C/T cg01189475 chr2:152685088 ARL5A 0.62 7.33 0.37 1.65e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs17253792 0.822 rs78323463 chr14:56045451 T/G cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg08499158 chr17:42289980 UBTF -0.52 -8.52 -0.42 5.11e-16 Total body bone mineral density; LIHC cis rs8044995 0.517 rs61593058 chr16:68384496 T/C cg09835421 chr16:68378352 PRMT7 -0.63 -7.96 -0.4 2.5e-14 Schizophrenia; LIHC cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg10862848 chr6:42927986 GNMT 0.27 6.29 0.32 9.88e-10 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs12310956 0.532 rs10844720 chr12:33987859 G/T cg26384229 chr12:38710491 ALG10B 0.49 6.69 0.34 9.11e-11 Morning vs. evening chronotype; LIHC cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs11229555 0.645 rs11229450 chr11:58201629 G/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1018836 0.923 rs1476427 chr8:91552791 A/G cg16814680 chr8:91681699 NA 0.62 10.1 0.48 3.55e-21 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26695837 chr4:37688098 RELL1 -0.51 -6.5 -0.33 2.85e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs28374715 0.562 rs8036686 chr15:41550333 C/T cg18705301 chr15:41695430 NDUFAF1 -0.4 -5.8 -0.3 1.48e-8 Ulcerative colitis; LIHC cis rs6062302 0.522 rs2282157 chr20:62227180 C/G cg09650180 chr20:62225654 GMEB2 -0.39 -6.01 -0.31 4.72e-9 Glioblastoma; LIHC cis rs2645694 0.651 rs2703144 chr4:77830505 C/G cg06046430 chr4:77819534 ANKRD56 0.51 6.26 0.32 1.12e-9 Emphysema distribution in smoking; LIHC cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg07424592 chr7:64974309 NA 0.81 9.47 0.46 4.62e-19 Diabetic kidney disease; LIHC cis rs9309473 0.687 rs6748040 chr2:73609928 A/G cg20560298 chr2:73613845 ALMS1 0.47 7.61 0.38 2.64e-13 Metabolite levels; LIHC cis rs7546668 1.000 rs1129347 chr1:15817334 G/A cg11706911 chr1:15910989 AGMAT 0.4 6.04 0.31 3.95e-9 Glomerular filtration rate (creatinine); LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg11905131 chr22:24372483 LOC391322 -0.78 -12.24 -0.55 8.29e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs72781680 0.611 rs6720131 chr2:24364736 C/T cg06627628 chr2:24431161 ITSN2 -0.64 -7.39 -0.37 1.16e-12 Lymphocyte counts; LIHC cis rs6138458 0.743 rs3746330 chr20:24999795 A/G cg26195577 chr20:24973756 C20orf3 0.88 11.08 0.51 1.38e-24 Blood protein levels; LIHC cis rs4319547 0.695 rs4758643 chr12:122924819 A/T cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.46 -0.37 7.12e-13 Body mass index; LIHC trans rs7618501 1.000 rs4855867 chr3:49745822 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg11905131 chr22:24372483 LOC391322 0.59 8.09 0.4 1.06e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg13271783 chr10:134563150 INPP5A -0.56 -7.07 -0.36 8.51e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2072499 0.838 rs2758619 chr1:156162559 A/G cg24450063 chr1:156163899 SLC25A44 1.07 18.45 0.71 3.04e-53 Testicular germ cell tumor; LIHC cis rs6665290 0.669 rs3795445 chr1:227180947 A/C cg10327440 chr1:227177885 CDC42BPA -1.09 -22.76 -0.78 1.8e-70 Myeloid white cell count; LIHC trans rs11098499 0.874 rs13123591 chr4:120105990 T/G cg25214090 chr10:38739885 LOC399744 0.45 7.28 0.37 2.35e-12 Corneal astigmatism; LIHC cis rs1707322 0.752 rs11211146 chr1:46109794 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.56 0.38 3.67e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6960043 0.748 rs10228561 chr7:15063961 C/T cg19272540 chr7:15055459 NA -0.24 -6.64 -0.34 1.25e-10 Type 2 diabetes; LIHC cis rs736408 0.924 rs2535629 chr3:52833219 C/T cg18404041 chr3:52824283 ITIH1 -0.52 -8.55 -0.42 4.04e-16 Bipolar disorder; LIHC cis rs17253792 0.545 rs35418987 chr14:56017407 T/G cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg16405210 chr4:1374714 KIAA1530 -0.52 -7.72 -0.39 1.26e-13 Obesity-related traits; LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg06558623 chr16:89946397 TCF25 0.92 14.08 0.61 8.22e-36 Skin colour saturation; LIHC trans rs17685 0.753 rs4728550 chr7:75670988 C/A cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.75 -0.71 1.96e-54 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs561341 0.883 rs72821942 chr17:30234460 C/T cg20587970 chr11:113659929 NA -0.74 -8.45 -0.42 8.62e-16 Hip circumference adjusted for BMI; LIHC cis rs6570726 0.791 rs2096201 chr6:145934273 C/T cg23711669 chr6:146136114 FBXO30 0.73 12.39 0.56 2.28e-29 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.591 rs11040589 chr11:49862449 A/G cg15704280 chr7:45808275 SEPT13 -0.95 -19.96 -0.73 2.55e-59 Height; LIHC cis rs477692 0.569 rs10764883 chr10:131307817 A/G cg05714579 chr10:131428358 MGMT 0.41 6.52 0.33 2.54e-10 Response to temozolomide; LIHC trans rs11098499 0.908 rs28559989 chr4:120386627 C/T cg25214090 chr10:38739885 LOC399744 0.61 9.99 0.48 8.49e-21 Corneal astigmatism; LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC cis rs9393777 0.623 rs9358947 chr6:26479000 G/A cg12826209 chr6:26865740 GUSBL1 0.66 6.97 0.35 1.65e-11 Intelligence (multi-trait analysis); LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.4 -0.33 5e-10 Total body bone mineral density; LIHC cis rs3748682 1.000 rs3748682 chr1:38279987 C/T cg12658694 chr1:38397304 INPP5B -0.46 -6.29 -0.32 9.53e-10 Hypothyroidism; LIHC cis rs3859192 0.539 rs2302774 chr17:38183090 G/T cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.98 0.65 2.62e-43 White blood cell count; LIHC cis rs11718455 0.883 rs6795366 chr3:44005735 C/T cg08738300 chr3:44038990 NA 0.5 8.87 0.43 4.04e-17 Coronary artery disease; LIHC trans rs1814175 0.618 rs7483546 chr11:49714784 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.18e-11 Height; LIHC cis rs7772486 0.790 rs1062067 chr6:146207563 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.8 -0.3 1.51e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs651907 0.557 rs11720745 chr3:101441690 G/A cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.74 -0.3 2.04e-8 Colorectal cancer; LIHC cis rs1801251 1.000 rs3817311 chr2:233612557 C/T cg08000102 chr2:233561755 GIGYF2 0.76 11.47 0.53 5.31e-26 Coronary artery disease; LIHC cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg22907277 chr7:1156413 C7orf50 0.73 5.76 0.3 1.88e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9311474 0.502 rs4687624 chr3:52563572 C/T cg18404041 chr3:52824283 ITIH1 -0.44 -7.01 -0.35 1.29e-11 Electroencephalogram traits; LIHC cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.1 0.44 7.66e-18 Platelet count; LIHC cis rs2303759 0.874 rs8108669 chr19:49845895 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.92 0.43 2.94e-17 Multiple sclerosis; LIHC cis rs1790761 0.667 rs591434 chr11:67337814 C/T cg01069141 chr11:67398826 TBX10;NUDT8 0.38 6.69 0.34 8.86e-11 Mean corpuscular volume; LIHC cis rs769267 0.895 rs1858999 chr19:19497669 C/G cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.09 -0.31 3.05e-9 Tonsillectomy; LIHC cis rs6933660 0.745 rs6912830 chr6:151743629 A/C cg14262678 chr6:151773367 RMND1;C6orf211 0.52 7.88 0.39 4.47e-14 Menarche (age at onset); LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg24693881 chr1:107596107 NA 0.56 9.87 0.47 2.22e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7772486 0.875 rs7739371 chr6:146424353 C/G cg05347473 chr6:146136440 FBXO30 0.39 6.16 0.32 2.01e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7727544 0.735 rs270605 chr5:131651811 C/T cg24060327 chr5:131705240 SLC22A5 -0.6 -8.51 -0.42 5.35e-16 Blood metabolite levels; LIHC cis rs9324022 0.929 rs59488041 chr14:101180041 T/A cg18089426 chr14:101175970 NA 0.43 5.87 0.3 1.01e-8 Plateletcrit; LIHC cis rs35110281 0.805 rs2838330 chr21:45023876 T/A cg21573476 chr21:45109991 RRP1B -0.53 -9.94 -0.47 1.25e-20 Mean corpuscular volume; LIHC cis rs2412488 0.853 rs12507739 chr4:54352768 C/T cg22241045 chr4:54363911 LNX1 -0.44 -7.05 -0.36 9.9e-12 DNA methylation (variation); LIHC cis rs7584330 0.554 rs7582964 chr2:238385766 C/T cg08992911 chr2:238395768 MLPH -0.62 -6.72 -0.34 7.72e-11 Prostate cancer; LIHC cis rs600806 0.815 rs10858088 chr1:109923586 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs7674212 0.539 rs2866635 chr4:104121576 G/A cg16532752 chr4:104119610 CENPE -0.46 -7.2 -0.36 3.76e-12 Type 2 diabetes; LIHC cis rs2304069 0.545 rs12153714 chr5:149395254 A/G cg12661370 chr5:149340060 SLC26A2 0.54 8.06 0.4 1.28e-14 HIV-1 control; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17524854 chr12:67663046 CAND1 0.48 7.83 0.39 5.99e-14 Cognitive function; LIHC cis rs2645694 0.626 rs2645708 chr4:77822682 G/A cg03477792 chr4:77819574 ANKRD56 0.57 8.22 0.41 4.29e-15 Emphysema distribution in smoking; LIHC cis rs72627509 1.000 rs72627509 chr4:57839051 C/G cg26694713 chr4:57773883 REST 0.67 9.01 0.44 1.44e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg07677032 chr17:61819896 STRADA 0.42 6.2 0.32 1.61e-9 Prudent dietary pattern; LIHC cis rs1577917 0.740 rs2475792 chr6:86392102 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.37 6.65 0.34 1.19e-10 Response to antipsychotic treatment; LIHC cis rs9640161 0.789 rs34311995 chr7:150059255 T/C cg21361702 chr7:150065534 REPIN1 0.53 7.56 0.38 3.75e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg27170947 chr2:26402098 FAM59B -0.66 -8.2 -0.41 4.88e-15 Gut microbiome composition (summer); LIHC cis rs7777484 0.571 rs2527686 chr7:2834413 G/A cg18446336 chr7:2847575 GNA12 -0.33 -6.5 -0.33 2.78e-10 Height; LIHC cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg06481639 chr22:41940642 POLR3H 0.71 7.21 0.36 3.53e-12 Vitiligo; LIHC cis rs9611565 0.649 rs139559 chr22:42191636 A/G cg03806693 chr22:41940476 POLR3H -0.79 -8.69 -0.43 1.52e-16 Vitiligo; LIHC cis rs826838 1.000 rs826891 chr12:39100824 A/G cg26384229 chr12:38710491 ALG10B -0.57 -8.73 -0.43 1.12e-16 Heart rate; LIHC cis rs1198430 0.636 rs2156087 chr1:23743581 C/G cg13183780 chr1:23809682 ASAP3 0.35 6.3 0.32 9.34e-10 Total cholesterol levels; LIHC cis rs1775715 0.870 rs10827003 chr10:32266216 A/G cg14930904 chr10:32216787 ARHGAP12 0.39 6.92 0.35 2.21e-11 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25184507 chr17:7760147 CYB5D1;LSMD1 0.47 6.8 0.35 4.69e-11 Pancreatic cancer; LIHC cis rs765787 0.530 rs2668751 chr15:45517293 T/C cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC trans rs11098499 0.865 rs28845498 chr4:120405186 G/A cg25214090 chr10:38739885 LOC399744 0.58 9.5 0.46 3.69e-19 Corneal astigmatism; LIHC cis rs208520 0.661 rs704519 chr6:66801136 T/C cg07460842 chr6:66804631 NA -0.84 -9.29 -0.45 1.86e-18 Exhaled nitric oxide output; LIHC cis rs897984 0.568 rs67456613 chr16:30888295 G/A cg02466173 chr16:30829666 NA -0.43 -6.4 -0.33 5.11e-10 Dementia with Lewy bodies; LIHC cis rs1215050 0.791 rs7688192 chr4:98900798 G/T cg05340658 chr4:99064831 C4orf37 -0.39 -5.82 -0.3 1.34e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs155076 1.000 rs2478824 chr13:21844144 G/C cg11317459 chr13:21872234 NA -1.17 -13.06 -0.58 6.87e-32 White matter hyperintensity burden; LIHC cis rs3741404 0.825 rs60452247 chr11:63981507 G/A cg04317338 chr11:64019027 PLCB3 0.48 6.57 0.33 1.91e-10 Platelet count; LIHC cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg25894440 chr7:65020034 NA 0.52 5.94 0.31 7.16e-9 Diabetic kidney disease; LIHC trans rs11098499 0.754 rs7689729 chr4:120256192 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.26 0.41 3.23e-15 Corneal astigmatism; LIHC cis rs10170846 0.893 rs1447108 chr2:223542231 A/G cg25565276 chr2:223520875 FARSB 0.63 9.29 0.45 1.82e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs17685 0.753 rs3757593 chr7:75678735 G/A cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.29 0.32 9.72e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs807669 0.548 rs5748028 chr22:19172281 G/A cg02655711 chr22:19163373 SLC25A1 0.36 6.3 0.32 8.94e-10 Metabolite levels; LIHC cis rs6088590 0.735 rs6060001 chr20:33294353 C/T cg08999081 chr20:33150536 PIGU -0.55 -9.7 -0.46 7.95e-20 Coronary artery disease; LIHC cis rs6964587 0.933 rs6465350 chr7:91768615 G/A cg17063962 chr7:91808500 NA 1.05 21.17 0.75 3.6e-64 Breast cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25310909 chr1:165738087 TMCO1 -0.52 -6.24 -0.32 1.26e-9 Systolic blood pressure; LIHC cis rs1866706 0.739 rs7116989 chr11:12856087 G/A cg25843174 chr11:12811716 TEAD1 -0.32 -6.69 -0.34 8.89e-11 Intelligence (multi-trait analysis); LIHC cis rs2380220 0.606 rs7754906 chr6:95992429 C/T cg15832292 chr6:96025679 MANEA 0.57 7.81 0.39 7.06e-14 Behavioural disinhibition (generation interaction); LIHC cis rs600806 0.627 rs2359652 chr1:110008720 T/A cg02415029 chr1:110025642 ATXN7L2 -0.49 -6.31 -0.32 8.63e-10 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18864164 chr10:115934049 MIR2110;C10orf118 0.42 6.21 0.32 1.54e-9 Pancreatic cancer; LIHC cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg25072359 chr17:41440525 NA 0.38 6.06 0.31 3.67e-9 Menopause (age at onset); LIHC trans rs877282 0.853 rs7083589 chr10:754494 G/A cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs2573652 1.000 rs12441080 chr15:100516968 A/G cg09918751 chr15:100517450 ADAMTS17 0.84 16.07 0.66 1.06e-43 Height; LIHC cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg12463550 chr7:65579703 CRCP -0.66 -6.96 -0.35 1.78e-11 Diabetic kidney disease; LIHC cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg03452623 chr4:187889614 NA 0.3 7.51 0.38 5.34e-13 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06185204 chr15:80351985 ZFAND6 0.42 6.96 0.35 1.75e-11 Pancreatic cancer; LIHC cis rs6831352 0.918 rs17218141 chr4:100055908 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs9443189 0.855 rs1321161 chr6:76454182 G/A cg01950844 chr6:76311363 SENP6 -0.53 -6.7 -0.34 8.63e-11 Prostate cancer; LIHC cis rs7044106 0.791 rs7036766 chr9:123479621 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 8.09 0.4 1.02e-14 Hip circumference adjusted for BMI; LIHC cis rs3540 0.513 rs2601154 chr15:90894284 T/C cg22089800 chr15:90895588 ZNF774 0.69 9.32 0.45 1.49e-18 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs7523273 0.586 rs2796264 chr1:207919968 A/G cg22525895 chr1:207977042 MIR29B2 0.66 10.72 0.5 2.54e-23 Schizophrenia; LIHC cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg19318889 chr4:1322082 MAEA -0.69 -10.59 -0.5 7.67e-23 Longevity; LIHC cis rs5769765 0.908 rs9627788 chr22:50300438 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -9.44 -0.45 5.85e-19 Schizophrenia; LIHC cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.59 0.38 3.03e-13 Bipolar disorder; LIHC cis rs17102423 0.692 rs762810 chr14:65544367 C/A cg11161011 chr14:65562177 MAX -0.52 -7.35 -0.37 1.48e-12 Obesity-related traits; LIHC cis rs2576037 0.526 rs2576051 chr18:44557884 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.68 -10.57 -0.5 8.92e-23 Personality dimensions; LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg14671364 chr1:107599128 PRMT6 0.48 6.96 0.35 1.71e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2842992 0.915 rs2758335 chr6:160111011 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.12 0.55 2.27e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs34779708 0.931 rs9663401 chr10:35278849 G/T cg03585969 chr10:35415529 CREM 0.87 13.04 0.58 7.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7587476 0.822 rs13018304 chr2:215682218 T/G cg04004882 chr2:215674386 BARD1 0.56 7.76 0.39 9.92e-14 Neuroblastoma; LIHC cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg21280719 chr6:42927975 GNMT -0.32 -7.05 -0.36 9.7e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2797160 0.935 rs1739372 chr6:126011325 G/A cg05901451 chr6:126070800 HEY2 0.44 7.32 0.37 1.81e-12 Endometrial cancer; LIHC cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg02951883 chr7:2050386 MAD1L1 -0.52 -7.86 -0.39 5.09e-14 Bipolar disorder and schizophrenia; LIHC trans rs1814175 0.615 rs12417290 chr11:49876951 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.43e-11 Height; LIHC cis rs4900538 0.819 rs72698595 chr14:102863099 G/A cg18135206 chr14:102964638 TECPR2 -0.71 -10.99 -0.51 2.85e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs11971779 0.680 rs7799598 chr7:139051833 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs7666738 0.830 rs35685312 chr4:98858521 G/A cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs10791097 0.568 rs4411284 chr11:130738568 A/C cg12179176 chr11:130786555 SNX19 0.81 13.04 0.58 7.7e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7584330 0.554 rs2325838 chr2:238386515 C/A cg08992911 chr2:238395768 MLPH 0.67 6.98 0.35 1.58e-11 Prostate cancer; LIHC cis rs4900538 0.928 rs1190551 chr14:102911508 A/G cg18135206 chr14:102964638 TECPR2 -0.94 -16.48 -0.67 2.58e-45 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs597539 0.580 rs7935851 chr11:68731122 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 9.87 0.47 2.2e-20 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg24693881 chr1:107596107 NA -0.55 -9.72 -0.47 6.99e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11671005 0.651 rs11878203 chr19:58920050 G/A cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg04944784 chr2:26401820 FAM59B -0.73 -9.13 -0.44 5.99e-18 Gut microbiome composition (summer); LIHC cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs7296418 0.961 rs61955196 chr12:123451018 G/C cg06742321 chr12:123595122 PITPNM2 0.33 5.99 0.31 5.32e-9 Platelet count; LIHC trans rs2018683 0.899 rs10269454 chr7:28978400 C/T cg19402173 chr7:128379420 CALU -0.4 -6.42 -0.33 4.69e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs875971 0.545 rs6460281 chr7:65681115 A/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.47 0.37 6.67e-13 Aortic root size; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg11557530 chr8:9911760 MSRA -0.52 -6.42 -0.33 4.51e-10 Monocyte count; LIHC cis rs10792665 0.512 rs10431163 chr11:82641500 G/A cg24227371 chr11:82718527 RAB30 -0.3 -7.02 -0.35 1.19e-11 Obesity-related traits; LIHC cis rs17401966 1.000 rs3753037 chr1:10355834 C/T cg15208524 chr1:10270712 KIF1B 0.44 6.5 0.33 2.77e-10 Hepatocellular carcinoma; LIHC cis rs2303745 0.589 rs11086065 chr19:17395003 A/G cg04248312 chr19:17393744 ANKLE1 -0.73 -12.09 -0.55 2.84e-28 Systemic lupus erythematosus; LIHC cis rs7116495 0.737 rs6592456 chr11:71737663 G/A cg26138937 chr11:71823887 C11orf51 -1.31 -10.43 -0.49 2.7e-22 Severe influenza A (H1N1) infection; LIHC cis rs4891159 0.790 rs660029 chr18:74149668 A/G cg24786174 chr18:74118243 ZNF516 0.79 15.51 0.64 1.81e-41 Longevity; LIHC cis rs12824058 0.831 rs12297939 chr12:130811923 G/C cg24838063 chr12:130822603 PIWIL1 0.67 9.86 0.47 2.31e-20 Menopause (age at onset); LIHC cis rs17106184 1.000 rs72898966 chr1:50969571 A/G cg07174182 chr1:51127561 FAF1 -0.58 -6.32 -0.32 8.21e-10 Type 2 diabetes; LIHC cis rs8062405 0.755 rs56272201 chr16:28580685 A/G cg00204512 chr16:28754710 NA 0.42 7.12 0.36 6.21e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg08219700 chr8:58056026 NA 0.52 6.92 0.35 2.19e-11 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.18 -0.55 1.37e-28 Alzheimer's disease; LIHC cis rs11190604 0.607 rs12220970 chr10:102175269 G/A cg07080220 chr10:102295463 HIF1AN 0.44 5.95 0.31 6.7e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10857712 0.703 rs1056521 chr10:135235890 T/C cg17796960 chr10:135278976 LOC619207 -0.35 -5.74 -0.3 2.1e-8 Systemic lupus erythematosus; LIHC cis rs9303280 0.806 rs62067034 chr17:38063738 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.9 0.3 8.79e-9 Self-reported allergy; LIHC cis rs477692 0.789 rs506915 chr10:131398005 A/G cg05714579 chr10:131428358 MGMT 0.45 7.44 0.37 8.25e-13 Response to temozolomide; LIHC cis rs9430161 0.611 rs35033941 chr1:11034382 C/T cg02454025 chr1:11042201 C1orf127 0.96 18.31 0.7 1.11e-52 Ewing sarcoma; LIHC cis rs2153535 0.601 rs9505474 chr6:8539794 C/G cg07606381 chr6:8435919 SLC35B3 0.79 11.44 0.53 7.27e-26 Motion sickness; LIHC trans rs1814175 0.791 rs10839395 chr11:49846274 G/T cg03929089 chr4:120376271 NA -0.9 -18.73 -0.71 2.22e-54 Height; LIHC trans rs3780486 0.846 rs10113903 chr9:33122645 C/G cg20290983 chr6:43655470 MRPS18A -1.14 -28.66 -0.84 6.41e-93 IgG glycosylation; LIHC cis rs8053891 0.756 rs12708922 chr16:72001629 A/G cg01557791 chr16:72042693 DHODH -0.47 -6.84 -0.35 3.7e-11 Coronary artery disease; LIHC cis rs2404602 0.716 rs17363713 chr15:76746128 G/C cg03037974 chr15:76606532 NA 0.81 16.67 0.67 4.37e-46 Blood metabolite levels; LIHC cis rs539096 0.500 rs2527776 chr1:44345292 G/A cg12908607 chr1:44402522 ARTN -0.48 -8.21 -0.41 4.57e-15 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.580 rs12603808 chr17:56578508 T/G cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.1 0.55 2.66e-28 Cognitive test performance; LIHC cis rs1401999 0.864 rs4148563 chr3:183725999 T/C cg20387954 chr3:183756860 HTR3D 0.28 5.98 0.31 5.57e-9 Anterior chamber depth; LIHC cis rs10924970 0.649 rs4659763 chr1:235447779 T/C cg26050004 chr1:235667680 B3GALNT2 0.4 5.77 0.3 1.8e-8 Asthma; LIHC cis rs79387448 0.745 rs59694233 chr2:103116521 G/A cg09003973 chr2:102972529 NA 0.81 7.09 0.36 7.59e-12 Gut microbiota (bacterial taxa); LIHC cis rs11673344 0.764 rs1644643 chr19:37463171 G/A cg27390819 chr19:37464633 NA -0.53 -6.29 -0.32 9.74e-10 Obesity-related traits; LIHC cis rs1008375 1.000 rs28545485 chr4:17645376 C/T cg04450456 chr4:17643702 FAM184B 0.34 5.74 0.3 2.05e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6754311 0.551 rs10928545 chr2:136501840 A/G cg07169764 chr2:136633963 MCM6 -0.75 -10.72 -0.5 2.67e-23 Mosquito bite size; LIHC cis rs9457247 0.637 rs9459846 chr6:167441023 T/G cg12798992 chr6:167411361 FGFR1OP 0.46 7.19 0.36 4.2e-12 Crohn's disease; LIHC trans rs1814175 0.817 rs80244685 chr11:49763292 C/A cg03929089 chr4:120376271 NA -0.82 -15.66 -0.65 4.84e-42 Height; LIHC trans rs1005277 0.579 rs1985707 chr10:38434098 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs7074356 0.915 rs1870146 chr10:82210379 A/G cg00277334 chr10:82204260 NA -0.75 -6.47 -0.33 3.33e-10 Borderline personality disorder; LIHC cis rs3741798 1.000 rs61922054 chr12:12499472 A/G cg08615371 chr12:12503544 MANSC1 0.9 7.28 0.37 2.29e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs936229 0.690 rs2472299 chr15:75033400 C/T cg14664628 chr15:75095509 CSK 0.82 13.59 0.59 5.96e-34 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs7677751 0.806 rs73252942 chr4:55104604 T/C cg17187183 chr4:55093834 PDGFRA 0.67 8.61 0.42 2.8e-16 Corneal astigmatism; LIHC cis rs1801251 0.778 rs709934 chr2:233733352 A/G cg25237894 chr2:233734115 C2orf82 -0.59 -11.77 -0.54 4.34e-27 Coronary artery disease; LIHC cis rs9486719 1.000 rs4343922 chr6:96876903 C/T cg06623918 chr6:96969491 KIAA0776 0.7 7.89 0.39 4.18e-14 Migraine;Coronary artery disease; LIHC cis rs10927875 0.632 rs2013745 chr1:16126676 G/A cg21385522 chr1:16154831 NA -1.03 -15.49 -0.64 2.33e-41 Dilated cardiomyopathy; LIHC cis rs736408 0.716 rs2300149 chr3:52822921 C/T cg18404041 chr3:52824283 ITIH1 -0.66 -11.03 -0.51 2.04e-24 Bipolar disorder; LIHC cis rs9381040 0.610 rs2268196 chr6:41021950 C/G cg04346459 chr6:41068666 NFYA;LOC221442 0.42 6.48 0.33 3.27e-10 Alzheimer's disease (late onset); LIHC cis rs77741769 0.571 rs11065282 chr12:121264415 G/T cg02419362 chr12:121203948 SPPL3 0.34 5.89 0.3 9.4e-9 Mean corpuscular volume; LIHC trans rs4824093 0.610 rs4824113 chr22:50284974 C/T cg09872104 chr7:134855509 C7orf49 -0.79 -6.33 -0.32 7.48e-10 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs7208859 0.673 rs423151 chr17:28952286 A/G cg14067834 chr17:29058358 SUZ12P 0.6 6.29 0.32 9.74e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8027181 0.839 rs7176235 chr15:72999104 A/G cg03441853 chr15:73075003 ADPGK 0.28 5.8 0.3 1.5e-8 Triglyceride levels; LIHC cis rs875971 0.660 rs62465434 chr7:66005152 A/C cg14393609 chr7:65229607 NA 0.37 5.84 0.3 1.22e-8 Aortic root size; LIHC cis rs7020830 1.000 rs7020830 chr9:37085184 A/T cg14294708 chr9:37120828 ZCCHC7 1.01 20.59 0.74 7.62e-62 Schizophrenia; LIHC trans rs4650994 0.967 rs6681043 chr1:178525957 A/G cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs8084351 0.577 rs9949928 chr18:50608590 A/G cg24270629 chr18:50823537 DCC 0.46 6.94 0.35 2.02e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9309473 0.607 rs7567017 chr2:73596270 C/T cg20560298 chr2:73613845 ALMS1 -0.45 -7.16 -0.36 5.13e-12 Metabolite levels; LIHC cis rs11048434 0.736 rs4309200 chr12:9121856 A/C cg04155231 chr12:9217510 LOC144571 0.31 5.9 0.3 8.77e-9 Sjögren's syndrome; LIHC cis rs4713118 0.513 rs149897 chr6:28006650 A/G cg16479474 chr6:28041457 NA 0.38 6.25 0.32 1.19e-9 Parkinson's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08655493 chr21:33765248 URB1;C21orf119 0.47 6.68 0.34 9.51e-11 Pancreatic cancer; LIHC cis rs1055129 0.537 rs2467100 chr17:73949038 C/G cg10935138 chr17:73851978 WBP2 0.49 7.3 0.37 2.01e-12 White matter hyperintensity burden; LIHC cis rs56104184 0.615 rs73061693 chr19:49399941 C/A cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg06634786 chr22:41940651 POLR3H -0.8 -8.58 -0.42 3.26e-16 Vitiligo; LIHC cis rs6120849 0.754 rs6119560 chr20:33606977 G/C cg24642439 chr20:33292090 TP53INP2 0.65 7.15 0.36 5.14e-12 Protein C levels; LIHC cis rs6942756 0.668 rs644723 chr7:129107881 C/T cg02491457 chr7:128862824 NA -0.55 -8.58 -0.42 3.43e-16 White matter hyperintensity burden; LIHC cis rs2302777 0.507 rs9889711 chr17:38108292 A/T cg17467752 chr17:38218738 THRA 0.4 6.05 0.31 3.79e-9 Multiple myeloma (hyperdiploidy); LIHC cis rs6089584 0.854 rs8117075 chr20:60613766 T/C cg13770153 chr20:60521292 NA -0.34 -6.74 -0.34 6.71e-11 Body mass index; LIHC cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC cis rs853679 0.542 rs6934769 chr6:28090931 A/G cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs9828933 0.766 rs3774725 chr3:63974258 T/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.76 -9.91 -0.47 1.62e-20 Type 2 diabetes; LIHC cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC cis rs2073300 0.609 rs6137927 chr20:23372513 A/G cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11626933 0.959 rs8005973 chr14:90774951 C/T cg07150772 chr14:90864620 CALM1 -0.42 -5.95 -0.31 6.5e-9 Gut microbiota (bacterial taxa); LIHC cis rs7659604 0.540 rs4361412 chr4:122669403 C/T cg19671926 chr4:122722719 EXOSC9 0.46 6.69 0.34 9.39e-11 Type 2 diabetes; LIHC cis rs1552244 0.572 rs113406084 chr3:10170190 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs25645 0.771 rs11078936 chr17:38197914 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.76 14.39 0.61 4.75e-37 Myeloid white cell count; LIHC cis rs2723064 0.516 rs17849707 chr2:65298839 A/G cg05010058 chr2:65284262 CEP68 0.37 5.87 0.3 1.02e-8 Atrial fibrillation; LIHC cis rs7959452 0.868 rs10878967 chr12:69740869 T/C cg22834771 chr12:69754056 YEATS4 -0.37 -5.96 -0.31 6.19e-9 Blood protein levels; LIHC cis rs875971 0.642 rs35526611 chr7:66094008 C/T cg00343986 chr7:65444356 GUSB -0.39 -5.83 -0.3 1.31e-8 Aortic root size; LIHC trans rs11722228 0.549 rs73212830 chr4:10078759 A/T cg26043149 chr18:55253948 FECH 0.94 13.54 0.59 1.01e-33 Gout;Urate levels;Serum uric acid levels; LIHC cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg17554472 chr22:41940697 POLR3H 0.56 6.23 0.32 1.34e-9 Vitiligo; LIHC cis rs10870270 1.000 rs7077744 chr10:133770201 C/T cg26149184 chr10:133730230 NA 0.47 7.49 0.38 5.75e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC trans rs637571 0.607 rs589253 chr11:65693080 G/A cg17712092 chr4:129076599 LARP1B 0.81 14.22 0.61 2.18e-36 Eosinophil percentage of white cells; LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.89 -0.3 9.01e-9 Total body bone mineral density; LIHC cis rs10883723 0.518 rs10786679 chr10:104315667 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 10.4 0.49 3.4e-22 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg11502198 chr6:26597334 ABT1 0.59 9.04 0.44 1.22e-17 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg02782426 chr3:40428986 ENTPD3 0.34 6.18 0.32 1.77e-9 Renal cell carcinoma; LIHC cis rs3936840 0.548 rs1190545 chr14:102904179 G/C cg18135206 chr14:102964638 TECPR2 -0.4 -5.73 -0.3 2.24e-8 Plateletcrit; LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg09455208 chr3:40491958 NA 0.38 7.55 0.38 3.96e-13 Renal cell carcinoma; LIHC cis rs1577917 0.883 rs12214536 chr6:86790310 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -6.96 -0.35 1.75e-11 Response to antipsychotic treatment; LIHC cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.94 -0.31 7.07e-9 Colorectal cancer; LIHC trans rs2727020 0.688 rs2734002 chr11:49234162 A/G cg15704280 chr7:45808275 SEPT13 0.88 16.22 0.66 2.85e-44 Coronary artery disease; LIHC cis rs3806843 0.676 rs778593 chr5:140027216 T/C cg16577123 chr5:140027231 NDUFA2;IK -0.42 -6.06 -0.31 3.63e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs6964587 0.967 rs10246036 chr7:91558523 G/A cg17063962 chr7:91808500 NA -1.02 -19.52 -0.73 1.47e-57 Breast cancer; LIHC cis rs7312774 0.748 rs10492214 chr12:107294758 T/C cg16260113 chr12:107380972 MTERFD3 0.8 10.51 0.49 1.37e-22 Severe influenza A (H1N1) infection; LIHC cis rs12464559 0.649 rs7557801 chr2:152586658 G/A cg01189475 chr2:152685088 ARL5A 0.67 7.78 0.39 8.52e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs4788570 0.584 rs6499534 chr16:71755278 C/G cg06353428 chr16:71660113 MARVELD3 1.38 15.03 0.63 1.45e-39 Intelligence (multi-trait analysis); LIHC cis rs12464559 0.522 rs10180065 chr2:152619007 A/G cg01189475 chr2:152685088 ARL5A -0.72 -8.74 -0.43 1.07e-16 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs1707322 1.000 rs785480 chr1:46492164 C/G cg06784218 chr1:46089804 CCDC17 0.36 6.51 0.33 2.61e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs317689 0.608 rs650198 chr12:69674595 C/T cg14784868 chr12:69753453 YEATS4 0.56 7.92 0.39 3.35e-14 Response to diuretic therapy; LIHC cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs4906332 0.933 rs34606394 chr14:103915636 G/A cg04998671 chr14:104000505 TRMT61A -0.45 -6.26 -0.32 1.15e-9 Coronary artery disease; LIHC cis rs2153535 0.580 rs7341382 chr6:8470549 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs7937682 0.961 rs7119563 chr11:111543916 T/A cg09085632 chr11:111637200 PPP2R1B 1.08 13.0 0.57 1.16e-31 Primary sclerosing cholangitis; LIHC cis rs6840360 0.593 rs7654294 chr4:152690975 T/C cg22705602 chr4:152727874 NA -0.4 -8.47 -0.42 7.54e-16 Intelligence (multi-trait analysis); LIHC cis rs10463316 0.894 rs12153347 chr5:150765471 C/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.66 -0.34 1.1e-10 Metabolite levels (Pyroglutamine); LIHC cis rs1008375 1.000 rs2159583 chr4:17658838 T/C cg02297831 chr4:17616191 MED28 0.51 7.98 0.4 2.24e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6684514 0.922 rs12128785 chr1:156269389 A/G cg16558208 chr1:156270281 VHLL 0.53 10.05 0.48 5.28e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs2180341 0.842 rs9372860 chr6:127546605 G/A cg27446573 chr6:127587934 RNF146 1.01 14.13 0.61 5.2e-36 Breast cancer; LIHC cis rs6840360 1.000 rs28637056 chr4:152652501 A/G cg22705602 chr4:152727874 NA -0.35 -7.37 -0.37 1.3e-12 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg06108461 chr20:60628389 TAF4 -1.0 -16.77 -0.67 1.79e-46 Body mass index; LIHC cis rs79387448 0.745 rs72993720 chr2:103121269 A/T cg09003973 chr2:102972529 NA 0.82 7.15 0.36 5.19e-12 Gut microbiota (bacterial taxa); LIHC cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg08888203 chr3:10149979 C3orf24 0.57 6.84 0.35 3.72e-11 Alzheimer's disease; LIHC cis rs11971779 0.680 rs7792752 chr7:139066196 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs7520050 0.966 rs6701614 chr1:46309420 G/C cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7107174 0.892 rs12284390 chr11:78103902 C/A cg02023728 chr11:77925099 USP35 0.46 8.45 0.42 8.7e-16 Testicular germ cell tumor; LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg20295408 chr7:1910781 MAD1L1 0.49 6.96 0.35 1.7e-11 Bipolar disorder and schizophrenia; LIHC cis rs7103648 1.000 rs2293579 chr11:47440758 G/A cg20307385 chr11:47447363 PSMC3 1.03 18.16 0.7 4.44e-52 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs11122272 0.735 rs2808583 chr1:231512587 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.57 -0.5 8.81e-23 Hemoglobin concentration; LIHC cis rs2000999 0.778 rs12445401 chr16:72148419 A/G cg01557791 chr16:72042693 DHODH -0.49 -7.03 -0.36 1.09e-11 Total cholesterol levels;Cholesterol, total;Blood protein levels;LDL cholesterol levels;Haptoglobin levels;LDL cholesterol; LIHC cis rs2710642 0.611 rs1527959 chr2:62867413 T/C cg17519650 chr2:63277830 OTX1 0.47 6.88 0.35 2.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs5015933 0.815 rs13297440 chr9:128087200 C/G cg14078157 chr9:128172775 NA -0.37 -5.85 -0.3 1.13e-8 Body mass index; LIHC cis rs7945705 0.747 rs11042150 chr11:9010819 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -8.73 -0.43 1.12e-16 Hemoglobin concentration; LIHC cis rs7208859 0.623 rs3752019 chr17:29151705 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.0 0.4 1.97e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10170846 0.626 rs9288575 chr2:223495133 A/C cg25565276 chr2:223520875 FARSB 1.0 14.61 0.62 6.55e-38 Schizophrenia (inflammation and infection response interaction); LIHC cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.95 9.45 0.45 5.67e-19 Platelet count; LIHC cis rs12802244 1 rs12802244 chr11:47932666 G/A cg20307385 chr11:47447363 PSMC3 -0.47 -6.52 -0.33 2.57e-10 Neuroticism; LIHC cis rs6500602 0.702 rs1051308 chr16:4560301 A/G cg08645402 chr16:4508243 NA -0.43 -7.85 -0.39 5.51e-14 Schizophrenia; LIHC cis rs1127311 0.846 rs61811388 chr1:154581231 G/C cg17218026 chr1:154582156 ADAR 0.36 7.19 0.36 4.12e-12 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs2816062 0.721 rs2816047 chr1:18893728 A/C cg18795169 chr1:18902165 NA -0.8 -17.92 -0.7 4.12e-51 Urate levels in lean individuals; LIHC cis rs11871801 0.915 rs647397 chr17:40679398 G/A cg14558262 chr17:40713999 COASY 0.56 7.65 0.38 2.11e-13 Crohn's disease; LIHC trans rs1814175 0.647 rs10769646 chr11:49992204 C/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs9814567 1.000 rs3846055 chr3:134203973 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.34 -0.56 3.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4555082 0.794 rs2735827 chr14:105710600 T/A cg06808227 chr14:105710500 BRF1 -0.53 -6.97 -0.35 1.68e-11 Mean platelet volume;Platelet distribution width; LIHC cis rs6930083 0.737 rs13196885 chr6:36632688 C/T cg08179530 chr6:36648295 CDKN1A -0.78 -13.02 -0.58 9.62e-32 Coronary artery disease; LIHC cis rs17826219 0.706 rs2322197 chr17:29105805 T/C cg14067834 chr17:29058358 SUZ12P 0.74 7.49 0.38 5.96e-13 Body mass index; LIHC cis rs2834188 0.883 rs16997869 chr21:34696867 C/T cg04842828 chr21:34696676 IFNAR1 -0.46 -6.22 -0.32 1.47e-9 Narcolepsy; LIHC trans rs7668874 0.779 rs9997910 chr4:116754123 C/A cg08917878 chr5:172668965 NA -0.3 -6.05 -0.31 3.89e-9 Response to platinum-based chemotherapy (carboplatin); LIHC trans rs2727020 0.513 rs10839307 chr11:49609843 A/C cg03929089 chr4:120376271 NA -0.91 -18.02 -0.7 1.61e-51 Coronary artery disease; LIHC cis rs6840360 0.571 rs2406976 chr4:152541056 G/C cg22705602 chr4:152727874 NA -0.32 -6.33 -0.32 7.5e-10 Intelligence (multi-trait analysis); LIHC cis rs875971 0.577 rs34888281 chr7:65585771 C/T cg11764359 chr7:65958608 NA -0.68 -8.79 -0.43 7.44e-17 Aortic root size; LIHC cis rs1538970 0.924 rs10890327 chr1:45891458 C/T cg24296786 chr1:45957014 TESK2 -0.5 -7.26 -0.37 2.63e-12 Platelet count; LIHC cis rs2070488 0.965 rs1058945 chr3:38532511 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.93 -15.87 -0.65 6.71e-43 Electrocardiographic conduction measures; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg21458073 chr7:35840614 SEPT7 -0.43 -6.5 -0.33 2.91e-10 Eotaxin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12580275 chr1:205744413 RAB7L1 0.51 7.01 0.35 1.26e-11 Pancreatic cancer; LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.965 rs6503726 chr17:41284742 T/C cg23758822 chr17:41437982 NA 0.86 15.55 0.64 1.35e-41 Menopause (age at onset); LIHC cis rs477895 0.713 rs3802933 chr11:63988102 C/T cg05555928 chr11:63887634 MACROD1 0.5 6.6 0.34 1.62e-10 Mean platelet volume; LIHC cis rs7129556 0.520 rs4945185 chr11:77318142 G/A cg03570279 chr11:77446074 RSF1 -0.35 -6.64 -0.34 1.2e-10 Weight loss (gastric bypass surgery); LIHC trans rs4650994 0.967 rs4650998 chr1:178531850 G/A cg05059571 chr16:84539110 KIAA1609 -0.37 -6.16 -0.32 2.06e-9 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7520050 0.743 rs61789988 chr1:46085242 G/C cg24296786 chr1:45957014 TESK2 0.42 6.37 0.33 6.25e-10 Red blood cell count;Reticulocyte count; LIHC cis rs941408 0.515 rs2110118 chr19:2775144 T/C cg06609049 chr19:2785107 THOP1 0.8 13.44 0.59 2.34e-33 Total cholesterol levels; LIHC cis rs6840360 1.000 rs6838966 chr4:152603475 C/T cg22705602 chr4:152727874 NA -0.31 -6.57 -0.33 1.83e-10 Intelligence (multi-trait analysis); LIHC cis rs611744 0.647 rs633901 chr8:109242981 G/T cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs6582630 0.555 rs10880520 chr12:38464111 C/T cg13010199 chr12:38710504 ALG10B 0.43 5.75 0.3 1.99e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg00809820 chr17:80708513 TBCD;FN3K -0.39 -6.94 -0.35 1.93e-11 Glycated hemoglobin levels; LIHC cis rs1555322 0.530 rs932562 chr20:33871310 T/C cg08210727 chr20:33865349 NA 0.51 5.89 0.3 9.43e-9 Attention deficit hyperactivity disorder; LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg02475777 chr4:1388615 CRIPAK 0.53 7.88 0.39 4.37e-14 Longevity; LIHC cis rs2153535 0.580 rs9505450 chr6:8469902 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs2075371 0.579 rs11766422 chr7:134018160 T/C cg20476274 chr7:133979776 SLC35B4 0.48 6.41 0.33 4.93e-10 Mean platelet volume; LIHC cis rs1003719 0.715 rs2156077 chr21:38539357 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.17e-24 Eye color traits; LIHC cis rs1707322 1.000 rs10158032 chr1:46332701 T/C cg06784218 chr1:46089804 CCDC17 0.35 6.23 0.32 1.37e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10857712 0.851 rs56153177 chr10:135216975 G/A cg19623624 chr10:135278901 LOC619207 -0.41 -6.31 -0.32 8.86e-10 Systemic lupus erythematosus; LIHC cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg04944784 chr2:26401820 FAM59B 0.72 9.24 0.45 2.63e-18 Gut microbiome composition (summer); LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg14828511 chr1:107599125 PRMT6 0.42 6.03 0.31 4.15e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7520050 0.966 rs785479 chr1:46492144 C/T cg03146154 chr1:46216737 IPP -0.38 -6.23 -0.32 1.38e-9 Red blood cell count;Reticulocyte count; LIHC cis rs910316 0.874 rs61980828 chr14:75630378 G/A cg11812906 chr14:75593930 NEK9 -0.72 -14.0 -0.6 1.6e-35 Height; LIHC cis rs9790314 0.589 rs4679662 chr3:160603024 T/C cg03342759 chr3:160939853 NMD3 0.56 7.31 0.37 1.87e-12 Morning vs. evening chronotype; LIHC cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg24101359 chr6:42928495 GNMT 0.46 5.86 0.3 1.08e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg18252515 chr7:66147081 NA 1.28 16.98 0.68 2.52e-47 Diabetic kidney disease; LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.77 -0.3 1.75e-8 Total body bone mineral density; LIHC trans rs1814175 0.817 rs10839351 chr11:49758153 C/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.29 -0.78 1.57e-72 Height; LIHC cis rs644799 0.662 rs35793328 chr11:95490896 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.87 14.32 0.61 8.9e-37 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.59 11.17 0.52 6.5e-25 Prudent dietary pattern; LIHC trans rs61931739 0.500 rs11053203 chr12:34456593 C/T cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs2758596 1.000 rs2842875 chr1:156161794 T/C cg24450063 chr1:156163899 SLC25A44 0.98 9.96 0.47 1.07e-20 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs763121 0.853 rs5750669 chr22:39080638 T/A cg14440974 chr22:39074834 NA -0.45 -7.35 -0.37 1.49e-12 Menopause (age at onset); LIHC trans rs72632736 0.881 rs72632727 chr1:4442940 T/A cg21153040 chr19:13985688 MIR181D -0.47 -6.24 -0.32 1.27e-9 Systemic juvenile idiopathic arthritis; LIHC trans rs9951602 0.512 rs12455566 chr18:76655926 A/G cg02800362 chr5:177631904 HNRNPAB 0.65 10.31 0.49 6.92e-22 Obesity-related traits; LIHC cis rs9457247 0.663 rs9459839 chr6:167431829 T/C cg07741184 chr6:167504864 NA 0.25 6.03 0.31 4.32e-9 Crohn's disease; LIHC cis rs2204008 0.837 rs12146734 chr12:38237079 A/G cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs11122272 0.735 rs2739518 chr1:231537633 C/T cg06096015 chr1:231504339 EGLN1 0.49 9.18 0.44 4.06e-18 Hemoglobin concentration; LIHC cis rs2439831 0.681 rs540388 chr15:43606494 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 17.37 0.68 6.68e-49 Lung cancer in ever smokers; LIHC cis rs7208859 0.673 rs8077116 chr17:29140162 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg08219700 chr8:58056026 NA 0.51 6.93 0.35 2.07e-11 Developmental language disorder (linguistic errors); LIHC cis rs66573146 0.656 rs66905212 chr4:6949508 G/C cg15105060 chr4:7024189 TBC1D14 -0.77 -6.38 -0.33 5.87e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12765878 1.000 rs3814220 chr10:105647300 A/G cg11005552 chr10:105648138 OBFC1 0.37 5.84 0.3 1.21e-8 Coronary artery disease; LIHC trans rs7618501 0.521 rs7615206 chr3:49937505 T/C cg21659725 chr3:3221576 CRBN 0.57 8.19 0.4 5.34e-15 Intelligence (multi-trait analysis); LIHC cis rs2273156 0.706 rs7144617 chr14:35498059 C/T cg16230307 chr14:35515116 FAM177A1 -0.44 -6.29 -0.32 9.76e-10 Immunoglobulin light chain (AL) amyloidosis; LIHC trans rs11098499 0.691 rs9307471 chr4:120261262 G/A cg25214090 chr10:38739885 LOC399744 0.44 7.32 0.37 1.76e-12 Corneal astigmatism; LIHC trans rs11098499 0.863 rs34308924 chr4:120481431 T/C cg25214090 chr10:38739885 LOC399744 0.59 9.36 0.45 1.08e-18 Corneal astigmatism; LIHC cis rs6089829 0.855 rs6090205 chr20:61665269 A/G cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs227584 0.663 rs2040810 chr17:42243771 C/T cg19774624 chr17:42201019 HDAC5 0.67 10.03 0.48 6.3e-21 Bone mineral density (hip);Bone mineral density; LIHC cis rs7223966 1.000 rs8066719 chr17:61825764 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.84 0.35 3.73e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9303401 0.573 rs35104446 chr17:57180234 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.89 12.08 0.55 3.32e-28 Cognitive test performance; LIHC cis rs703842 0.616 rs1875125 chr12:58227241 T/G cg04478727 chr12:58166393 METTL1;FAM119B 0.73 10.07 0.48 4.79e-21 Multiple sclerosis; LIHC cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg25072359 chr17:41440525 NA 0.38 6.18 0.32 1.82e-9 Menopause (age at onset); LIHC cis rs12701220 0.655 rs10241018 chr7:1144774 G/C cg04498913 chr7:1135747 C7orf50 0.44 6.94 0.35 2.03e-11 Bronchopulmonary dysplasia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg10651618 chr6:90122152 RRAGD 0.48 6.82 0.35 4.1e-11 Hepatitis; LIHC cis rs7223966 1.000 rs7220821 chr17:61704147 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 7.1 0.36 7.06e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6500602 0.702 rs3789038 chr16:4546586 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.54 -8.22 -0.41 4.31e-15 Schizophrenia; LIHC cis rs10504073 0.669 rs4493917 chr8:50015846 C/T cg00325661 chr8:49890786 NA 0.32 7.27 0.37 2.45e-12 Blood metabolite ratios; LIHC cis rs8081395 0.836 rs2150879 chr17:57859210 G/A cg02344993 chr17:57696989 CLTC -0.43 -7.16 -0.36 5.07e-12 White blood cell count; LIHC cis rs11758351 0.660 rs6918339 chr6:26211780 G/C cg16070018 chr6:26224392 HIST1H3E 0.42 5.89 0.3 9.11e-9 Gout;Renal underexcretion gout; LIHC cis rs807029 0.577 rs11190786 chr10:102757442 A/G cg25179470 chr10:102756915 LZTS2 0.45 6.26 0.32 1.17e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs12477438 1.000 rs995617 chr2:99857904 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.96 9.92 0.47 1.5e-20 Chronic sinus infection; LIHC cis rs6088813 1.000 rs6087704 chr20:34001058 C/T cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC cis rs7208859 0.673 rs999798 chr17:29158840 A/G cg14067834 chr17:29058358 SUZ12P 0.61 6.27 0.32 1.1e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12594515 1.000 rs57299255 chr15:45996532 C/A cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs2439831 0.702 rs2467402 chr15:44024490 A/C cg27015174 chr15:43622946 ADAL;LCMT2 -0.6 -8.51 -0.42 5.7e-16 Lung cancer in ever smokers; LIHC cis rs7945718 0.905 rs7949728 chr11:12728595 C/G cg25843174 chr11:12811716 TEAD1 0.35 7.96 0.4 2.52e-14 Educational attainment (years of education); LIHC cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg03034668 chr16:1723424 CRAMP1L -0.37 -6.6 -0.34 1.56e-10 Coronary artery disease; LIHC cis rs921968 0.541 rs2241527 chr2:219537224 A/G cg02985541 chr2:219472218 PLCD4 0.4 6.22 0.32 1.41e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs9916302 0.904 rs9898773 chr17:37532507 C/G cg07936489 chr17:37558343 FBXL20 0.85 13.68 0.59 2.7200000000000002e-34 Glomerular filtration rate (creatinine); LIHC trans rs79976124 0.797 rs78317899 chr6:66652896 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.77 0.34 5.54e-11 Type 2 diabetes; LIHC cis rs11148252 0.740 rs9536052 chr13:52960709 C/G cg00495681 chr13:53174319 NA -0.37 -5.94 -0.31 7.07e-9 Lewy body disease; LIHC trans rs61931739 0.534 rs1490109 chr12:34064077 T/C cg26384229 chr12:38710491 ALG10B 0.45 6.42 0.33 4.58e-10 Morning vs. evening chronotype; LIHC cis rs2842992 0.915 rs2842980 chr6:160100116 A/T cg16489826 chr6:160211363 TCP1;MRPL18 0.53 8.91 0.43 3.18e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs2991971 1.000 rs622798 chr1:46015271 T/G cg24296786 chr1:45957014 TESK2 0.5 7.18 0.36 4.44e-12 High light scatter reticulocyte count; LIHC cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg18305652 chr10:134549665 INPP5A 0.45 7.36 0.37 1.42e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7940866 0.845 rs2324314 chr11:130834589 A/C cg12179176 chr11:130786555 SNX19 0.53 7.7 0.38 1.5e-13 Schizophrenia; LIHC trans rs8002861 0.664 rs2184882 chr13:44450346 C/T cg17145862 chr1:211918768 LPGAT1 0.5 8.98 0.44 1.88e-17 Leprosy; LIHC cis rs9902453 0.780 rs7210991 chr17:28190961 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.33 0.55 3.71e-29 Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09060823 chr12:56862504 SPRYD4 0.56 7.79 0.39 8.2e-14 Pancreatic cancer; LIHC cis rs2257205 0.667 rs78253932 chr17:56804101 C/G cg12560992 chr17:57184187 TRIM37 0.72 7.9 0.39 3.98e-14 Pancreatic cancer; LIHC cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9790314 0.586 rs11710916 chr3:161130070 A/G cg03342759 chr3:160939853 NMD3 -0.55 -8.55 -0.42 4.24e-16 Morning vs. evening chronotype; LIHC cis rs12701220 0.655 rs6463317 chr7:1159243 G/A cg04498913 chr7:1135747 C7orf50 0.41 6.56 0.33 2.02e-10 Bronchopulmonary dysplasia; LIHC cis rs8072100 1.000 rs8065437 chr17:45721653 C/T cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.36 -5.93 -0.31 7.22e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs9733 0.596 rs6669369 chr1:150695892 C/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs9611565 0.559 rs5751160 chr22:42175695 A/G cg06634786 chr22:41940651 POLR3H 0.69 6.91 0.35 2.39e-11 Vitiligo; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05062814 chr6:39083007 C6orf64 0.43 6.11 0.31 2.73e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.1 -0.31 2.87e-9 Total body bone mineral density; LIHC cis rs79149102 0.737 rs75128970 chr15:75181397 C/T cg16226627 chr15:75307476 SCAMP5 0.43 6.1 0.31 2.9e-9 Lung cancer; LIHC cis rs10751667 0.666 rs6597958 chr11:978087 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg20887711 chr4:1340912 KIAA1530 0.8 12.72 0.57 1.27e-30 Longevity; LIHC cis rs7818688 0.745 rs73271178 chr8:95907230 C/T cg16049864 chr8:95962084 TP53INP1 0.58 6.64 0.34 1.25e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs783540 1.000 rs1259180 chr15:83244680 T/C cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.7 -0.34 8.5e-11 Schizophrenia; LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 7.93 0.39 3.23e-14 Height; LIHC trans rs16962242 1.000 rs10220266 chr13:104049586 G/C cg12071008 chr17:76457640 DNAH17 0.46 6.09 0.31 3.01e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg19318889 chr4:1322082 MAEA 0.67 10.61 0.5 6.29e-23 Longevity; LIHC cis rs763014 0.966 rs4984904 chr16:680809 C/G cg27189623 chr16:705930 WDR90 0.43 7.04 0.36 1.06e-11 Height; LIHC cis rs10508774 1.000 rs1333221 chr10:32903423 G/C cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs60871478 1.000 rs67721251 chr7:825114 T/C cg05535760 chr7:792225 HEATR2 0.75 10.55 0.5 1.04e-22 Cerebrospinal P-tau181p levels; LIHC cis rs9916302 0.904 rs9892055 chr17:37510402 C/T cg03013999 chr17:37608204 MED1 -0.35 -5.93 -0.31 7.41e-9 Glomerular filtration rate (creatinine); LIHC cis rs78456975 0.527 rs11885279 chr2:1560633 T/C cg01028140 chr2:1542097 TPO -0.42 -6.6 -0.34 1.58e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs875971 0.577 rs34888281 chr7:65585771 C/T cg14393609 chr7:65229607 NA -0.42 -6.03 -0.31 4.27e-9 Aortic root size; LIHC cis rs7927592 0.913 rs10896329 chr11:68250029 A/G cg20283391 chr11:68216788 NA -0.51 -7.64 -0.38 2.19e-13 Total body bone mineral density; LIHC cis rs9325144 0.600 rs12297194 chr12:38735803 A/G cg26384229 chr12:38710491 ALG10B -0.59 -8.4 -0.41 1.22e-15 Morning vs. evening chronotype; LIHC cis rs8044995 0.501 rs55793998 chr16:68378985 G/T cg09835421 chr16:68378352 PRMT7 -0.83 -9.98 -0.47 9.6e-21 Schizophrenia; LIHC cis rs6088580 0.634 rs6059835 chr20:33020141 A/G cg08999081 chr20:33150536 PIGU 0.67 13.26 0.58 1.15e-32 Glomerular filtration rate (creatinine); LIHC cis rs734999 1.000 rs734999 chr1:2513216 C/T cg18854424 chr1:2615690 NA 0.33 7.01 0.35 1.27e-11 Ulcerative colitis; LIHC cis rs240764 0.717 rs13208757 chr6:101175014 C/T cg09795085 chr6:101329169 ASCC3 -0.49 -7.06 -0.36 9.57e-12 Neuroticism; LIHC cis rs9916302 0.904 rs2338755 chr17:37419317 C/T cg03013999 chr17:37608204 MED1 -0.36 -6.12 -0.31 2.49e-9 Glomerular filtration rate (creatinine); LIHC cis rs1997103 1.000 rs6593237 chr7:55411015 T/C cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs10883723 0.737 rs11191312 chr10:104278601 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 9.93 0.47 1.38e-20 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2153535 0.526 rs1796689 chr6:8536433 A/C cg23788917 chr6:8435910 SLC35B3 0.59 8.13 0.4 7.9e-15 Motion sickness; LIHC cis rs7927771 0.832 rs11601603 chr11:47401171 A/C cg20307385 chr11:47447363 PSMC3 -0.44 -5.71 -0.3 2.45e-8 Subjective well-being; LIHC cis rs4969178 0.965 rs12450500 chr17:76395750 C/T cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs7197653 0.748 rs11350 chr16:68335392 A/G cg09835421 chr16:68378352 PRMT7 -0.74 -8.29 -0.41 2.58e-15 Magnesium levels; LIHC cis rs2204008 0.837 rs7315255 chr12:37949279 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.35e-8 Bladder cancer; LIHC cis rs1008375 0.966 rs2315645 chr4:17579678 G/C cg02297831 chr4:17616191 MED28 0.48 7.23 0.36 3.19e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2742417 0.624 rs2673029 chr3:45758867 A/G cg04837898 chr3:45731254 SACM1L -0.53 -8.89 -0.43 3.56e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs9393777 0.546 rs9366673 chr6:26893329 C/G cg12826209 chr6:26865740 GUSBL1 0.85 10.04 0.48 6.01e-21 Intelligence (multi-trait analysis); LIHC cis rs17685 0.671 rs60303271 chr7:75760008 A/G cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1707322 0.721 rs6699418 chr1:46100181 G/A cg06784218 chr1:46089804 CCDC17 0.4 7.58 0.38 3.39e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17376456 0.825 rs13155452 chr5:93164449 C/T cg25358565 chr5:93447407 FAM172A -0.96 -8.89 -0.43 3.6e-17 Diabetic retinopathy; LIHC cis rs2282802 0.685 rs11750229 chr5:139559014 T/G cg26211634 chr5:139558579 C5orf32 -0.38 -5.92 -0.3 7.76e-9 Intelligence (multi-trait analysis); LIHC cis rs57502260 0.573 rs11228294 chr11:68388567 C/T cg16797656 chr11:68205561 LRP5 0.4 5.9 0.3 8.53e-9 Total body bone mineral density (age 45-60); LIHC cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg13395646 chr4:1353034 KIAA1530 -0.39 -5.9 -0.3 8.64e-9 Longevity; LIHC cis rs826838 1.000 rs1843881 chr12:38733706 A/G cg13010199 chr12:38710504 ALG10B -0.68 -8.53 -0.42 4.65e-16 Heart rate; LIHC cis rs2204008 0.743 rs2132212 chr12:38039405 G/A cg26384229 chr12:38710491 ALG10B 0.5 6.84 0.35 3.73e-11 Bladder cancer; LIHC cis rs12188164 0.543 rs2434694 chr5:462734 C/T cg08916839 chr5:415575 AHRR 0.29 6.31 0.32 8.64e-10 Cystic fibrosis severity; LIHC trans rs1005277 0.579 rs2800485 chr10:38542588 G/A cg27523141 chr10:43048294 ZNF37B 0.4 6.76 0.34 6.02e-11 Extrinsic epigenetic age acceleration; LIHC cis rs12928939 0.859 rs11670 chr16:71679027 G/T cg03805757 chr16:71968109 PKD1L3 -0.67 -7.35 -0.37 1.43e-12 Post bronchodilator FEV1; LIHC cis rs3820068 0.705 rs11584398 chr1:15880275 G/A cg17385448 chr1:15911702 AGMAT 0.4 6.73 0.34 7.25e-11 Systolic blood pressure; LIHC cis rs10876993 0.890 rs115106209 chr12:58059331 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.57 -0.33 1.89e-10 Celiac disease or Rheumatoid arthritis; LIHC trans rs61931739 0.534 rs11053021 chr12:34111157 C/T cg26384229 chr12:38710491 ALG10B 0.53 7.2 0.36 3.91e-12 Morning vs. evening chronotype; LIHC cis rs7107174 1.000 rs10899458 chr11:78007451 A/T cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs6964587 1.000 rs10234434 chr7:91673308 A/T cg17063962 chr7:91808500 NA 1.0 19.08 0.72 8.79e-56 Breast cancer; LIHC cis rs798554 1.000 rs798544 chr7:2763102 A/G cg19717773 chr7:2847554 GNA12 0.42 6.78 0.34 5.37e-11 Height; LIHC cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg02951883 chr7:2050386 MAD1L1 -0.66 -10.61 -0.5 6.33e-23 Bipolar disorder and schizophrenia; LIHC cis rs1005277 0.579 rs2505248 chr10:38459097 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.44 -0.56 1.43e-29 Extrinsic epigenetic age acceleration; LIHC cis rs3793683 0.825 rs3793674 chr10:134555773 C/T cg06453172 chr10:134556979 INPP5A 0.54 7.71 0.38 1.41e-13 Migraine; LIHC cis rs13108904 0.901 rs1316393 chr4:1315619 A/G cg05665937 chr4:1216051 CTBP1 -0.44 -5.86 -0.3 1.08e-8 Obesity-related traits; LIHC cis rs1046896 0.739 rs2379358 chr17:80741612 G/A cg02711726 chr17:80685570 FN3KRP -0.49 -9.06 -0.44 1.03e-17 Glycated hemoglobin levels; LIHC trans rs783540 0.967 rs55972423 chr15:83258954 C/G cg18393722 chr15:85113863 UBE2QP1 -0.39 -6.68 -0.34 9.8e-11 Schizophrenia; LIHC cis rs2404602 0.631 rs9646213 chr15:76807672 G/C cg03037974 chr15:76606532 NA 0.79 16.09 0.66 8.87e-44 Blood metabolite levels; LIHC cis rs7395581 0.959 rs326222 chr11:47259668 A/G cg25783544 chr11:47291846 MADD -0.43 -6.37 -0.33 5.94e-10 HDL cholesterol; LIHC cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.67 0.38 1.81e-13 Electroencephalogram traits; LIHC cis rs6466055 0.777 rs2237613 chr7:104845253 G/C cg04380332 chr7:105027541 SRPK2 -0.36 -6.73 -0.34 7.2e-11 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03993166 chr15:101817914 SELS -0.54 -6.37 -0.33 6.18e-10 Systolic blood pressure; LIHC cis rs7512552 0.839 rs11581351 chr1:150440200 G/C cg15654264 chr1:150340011 RPRD2 0.68 11.25 0.52 3.39e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs7558233 0.614 rs4665214 chr2:23678795 A/G cg12626036 chr5:134662980 NA 0.41 6.21 0.32 1.5e-9 Cannabis use (initiation); LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs4862750 0.914 rs1991256 chr4:187875330 A/G cg03452623 chr4:187889614 NA -0.31 -7.92 -0.39 3.44e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs240764 0.644 rs4329121 chr6:101087507 G/C cg09795085 chr6:101329169 ASCC3 0.4 5.83 0.3 1.25e-8 Neuroticism; LIHC cis rs360798 0.553 rs7562734 chr2:63047973 G/C cg17519650 chr2:63277830 OTX1 -0.54 -8.15 -0.4 6.92e-15 Coronary artery disease; LIHC cis rs9549367 0.789 rs7338235 chr13:113888687 T/C cg18105134 chr13:113819100 PROZ -0.68 -11.73 -0.54 6.2e-27 Platelet distribution width; LIHC cis rs72627123 0.867 rs78496651 chr14:74480070 C/A cg11191049 chr14:74485465 ENTPD5;C14orf45 0.65 5.98 0.31 5.64e-9 Morning vs. evening chronotype; LIHC trans rs916888 0.738 rs199515 chr17:44856641 C/G cg07870213 chr5:140052090 DND1 -0.91 -9.7 -0.46 8.16e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7927771 0.524 rs2170815 chr11:47875910 T/C cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.29e-24 Subjective well-being; LIHC cis rs2066819 1.000 rs57279772 chr12:56698960 G/A cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs427394 0.659 rs274717 chr5:6721067 C/T cg10857441 chr5:6722123 POLS 0.38 6.38 0.33 5.62e-10 Menopause (age at onset); LIHC cis rs738322 0.555 rs5750549 chr22:38547172 C/T cg25457927 chr22:38595422 NA -0.4 -9.73 -0.47 6.5e-20 Cutaneous nevi; LIHC cis rs7953508 0.741 rs1498706 chr12:93996980 C/T cg18151635 chr12:93972918 NA -0.42 -6.17 -0.32 1.91e-9 Pubertal anthropometrics; LIHC cis rs1348850 0.958 rs1405713 chr2:178461560 G/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.2 0.52 4.99e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs11157436 0.918 rs12586393 chr14:22618769 G/A cg13567813 chr19:50879636 NR1H2 0.42 6.1 0.31 2.82e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs2573652 0.755 rs6598286 chr15:100515985 G/T cg09918751 chr15:100517450 ADAMTS17 -0.93 -17.77 -0.69 1.72e-50 Height; LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.46 7.22 0.36 3.39e-12 Bipolar disorder; LIHC cis rs919433 0.750 rs788010 chr2:198230949 T/C cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.8e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23640757 chr6:7889014 TXNDC5 0.4 6.06 0.31 3.65e-9 Longevity; LIHC cis rs7945718 0.934 rs7114040 chr11:12781659 C/T cg25843174 chr11:12811716 TEAD1 -0.28 -6.46 -0.33 3.52e-10 Educational attainment (years of education); LIHC cis rs1198430 0.925 rs487859 chr1:23801101 T/C cg19827787 chr1:23763612 ASAP3 0.38 6.68 0.34 9.55e-11 Total cholesterol levels; LIHC cis rs12022452 0.591 rs12049435 chr1:40990560 C/T cg25568243 chr1:40974465 DEM1 0.46 6.17 0.32 1.91e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6752107 0.967 rs56049444 chr2:234157688 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.52 7.68 0.38 1.69e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2303759 0.709 rs3760667 chr19:49814832 C/T cg22307029 chr19:49891270 CCDC155 0.56 8.66 0.42 1.88e-16 Multiple sclerosis; LIHC cis rs10791323 0.569 rs10791335 chr11:133739571 A/T cg06766960 chr11:133703094 NA -0.4 -6.04 -0.31 4.07e-9 Childhood ear infection; LIHC cis rs12586317 0.620 rs12588810 chr14:35554484 C/T cg16230307 chr14:35515116 FAM177A1 0.8 13.41 0.59 3.01e-33 Psoriasis; LIHC cis rs1018836 0.886 rs10283086 chr8:91616651 G/A cg16814680 chr8:91681699 NA -0.61 -9.68 -0.46 9.53e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs526821 0.574 rs11230156 chr11:55334809 A/G cg03929089 chr4:120376271 NA -0.45 -6.87 -0.35 3.05e-11 Pediatric bone mineral density (spine); LIHC cis rs2274273 0.712 rs6572999 chr14:55527374 T/C cg01864836 chr14:55583639 NA -0.38 -6.51 -0.33 2.74e-10 Protein biomarker; LIHC cis rs10751667 0.666 rs6597957 chr11:982294 T/A cg10932868 chr11:921992 NA 0.39 7.26 0.37 2.71e-12 Alzheimer's disease (late onset); LIHC cis rs7258465 1.000 rs34256197 chr19:18606472 G/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC trans rs66573146 0.831 rs68111914 chr4:6986677 C/T cg07817883 chr1:32538562 TMEM39B 1.08 9.42 0.45 6.98e-19 Granulocyte percentage of myeloid white cells; LIHC cis rs875971 0.545 rs1796219 chr7:66110964 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.32 -5.99 -0.31 5.3e-9 Aortic root size; LIHC cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg08392591 chr16:89556376 ANKRD11 0.52 8.12 0.4 8.42e-15 Multiple myeloma (IgH translocation); LIHC cis rs17286411 0.750 rs4788450 chr16:71955400 T/G cg06353428 chr16:71660113 MARVELD3 0.54 6.66 0.34 1.1e-10 Blood protein levels; LIHC cis rs1816752 0.870 rs9581029 chr13:24999285 C/A cg02811702 chr13:24901961 NA 0.24 5.79 0.3 1.6e-8 Obesity-related traits; LIHC cis rs1215050 0.740 rs1648568 chr4:98957619 A/G cg05340658 chr4:99064831 C4orf37 -0.4 -6.26 -0.32 1.13e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4906332 1.000 rs78316803 chr14:103942863 A/G cg04998671 chr14:104000505 TRMT61A -0.46 -6.21 -0.32 1.53e-9 Coronary artery disease; LIHC cis rs1401999 0.807 rs9869029 chr3:183735286 C/G cg01324343 chr3:183735012 ABCC5 0.78 12.98 0.57 1.38e-31 Anterior chamber depth; LIHC cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg18765753 chr7:1198926 ZFAND2A -0.46 -8.17 -0.4 5.9e-15 Longevity;Endometriosis; LIHC cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg07636037 chr3:49044803 WDR6 0.75 12.46 0.56 1.27e-29 Menarche (age at onset); LIHC cis rs11167764 1.000 rs10057309 chr5:141479870 T/C cg23435118 chr5:141488016 NDFIP1 -0.44 -6.05 -0.31 3.89e-9 Crohn's disease; LIHC cis rs11864453 0.679 rs2303285 chr16:72124495 A/C cg01557791 chr16:72042693 DHODH -0.42 -6.97 -0.35 1.63e-11 Fibrinogen levels; LIHC cis rs11098699 0.821 rs13141181 chr4:124212126 G/A cg09941581 chr4:124220074 SPATA5 0.33 6.61 0.34 1.47e-10 Mosquito bite size; LIHC cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg02290350 chr8:58132656 NA 0.51 10.45 0.49 2.28e-22 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg04234412 chr22:24373322 LOC391322 -0.68 -9.97 -0.47 1.01e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg06238570 chr21:40685208 BRWD1 -0.65 -7.76 -0.39 9.81e-14 Cognitive function; LIHC cis rs9911578 1.000 rs6503866 chr17:56619581 C/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.73 -0.69 2.35e-50 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.559 rs445434 chr6:88041849 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.36 6.87 0.35 3.05e-11 Monocyte percentage of white cells; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg13976866 chr7:128696069 LOC286016;TNPO3 0.37 6.1 0.31 2.91e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2204008 0.702 rs8175764 chr12:38363690 T/C cg26384229 chr12:38710491 ALG10B 0.57 7.83 0.39 6.11e-14 Bladder cancer; LIHC trans rs8113308 1.000 rs6509600 chr19:52442589 G/T cg14959425 chr7:20447707 ITGB8 -0.44 -6.09 -0.31 3.03e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs9916302 0.904 rs801426 chr17:37441109 C/T cg00129232 chr17:37814104 STARD3 0.38 6.16 0.32 2.05e-9 Glomerular filtration rate (creatinine); LIHC cis rs1200821 0.535 rs1208783 chr10:37767467 A/G cg00409905 chr10:38381863 ZNF37A -0.37 -5.85 -0.3 1.13e-8 Hemostatic factors and hematological phenotypes; LIHC cis rs12188164 0.543 rs2672722 chr5:453567 G/A cg26072250 chr5:443457 EXOC3;C5orf55 0.47 7.01 0.35 1.24e-11 Cystic fibrosis severity; LIHC cis rs7618501 0.633 rs4688757 chr3:50035323 T/C cg21467203 chr3:49911342 NA -0.44 -7.84 -0.39 5.69e-14 Intelligence (multi-trait analysis); LIHC cis rs807669 0.802 rs762528 chr22:19166680 A/G cg02655711 chr22:19163373 SLC25A1 0.74 11.2 0.52 5.17e-25 Metabolite levels; LIHC cis rs7044106 0.762 rs13291660 chr9:123392748 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.59 0.5 7.71e-23 Hip circumference adjusted for BMI; LIHC trans rs73389468 1 rs73389468 chr10:134295815 C/T cg14435695 chr11:71950660 PHOX2A -0.78 -6.1 -0.31 2.85e-9 Periodontitis (CDC/AAP); LIHC cis rs6723226 0.503 rs4952262 chr2:32597234 G/A cg02381751 chr2:32503542 YIPF4 -0.54 -7.45 -0.37 7.88e-13 Intelligence (multi-trait analysis); LIHC cis rs950776 0.518 rs12916999 chr15:78826912 C/T cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs6088580 0.634 rs62212172 chr20:32987705 G/A cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs155076 0.938 rs485361 chr13:21845826 G/T cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.3e-30 White matter hyperintensity burden; LIHC cis rs7089973 0.624 rs11196930 chr10:116583596 C/T cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs597539 0.652 rs513359 chr11:68669496 A/T cg06028808 chr11:68637592 NA -0.44 -5.79 -0.3 1.59e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs506338 0.517 rs530252 chr11:64443465 T/C cg08800856 chr11:64428347 NRXN2 0.39 6.13 0.31 2.48e-9 Body mass index;Urate levels; LIHC cis rs35110281 0.774 rs162344 chr21:44954522 G/A cg04455712 chr21:45112962 RRP1B 0.44 7.4 0.37 1.07e-12 Mean corpuscular volume; LIHC cis rs798554 0.757 rs1182188 chr7:2869985 T/C cg19346786 chr7:2764209 NA -0.41 -5.78 -0.3 1.64e-8 Height; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs2963155 0.518 rs10482614 chr5:142782402 C/T cg17617527 chr5:142782415 NR3C1 0.94 10.32 0.49 6.35e-22 Breast cancer; LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.02 23.08 0.78 1.03e-71 Height; LIHC cis rs7520050 0.966 rs6656992 chr1:46333068 C/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 4.13e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10791097 0.690 rs12286234 chr11:130730528 T/C cg09137382 chr11:130731461 NA 0.42 6.35 0.32 6.9e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs12579753 0.879 rs7958566 chr12:82131478 A/T cg07988820 chr12:82153109 PPFIA2 -0.49 -6.16 -0.32 2.04e-9 Resting heart rate; LIHC cis rs2228479 0.850 rs62052660 chr16:89847420 T/A cg00800038 chr16:89945340 TCF25 -0.62 -9.01 -0.44 1.47e-17 Skin colour saturation; LIHC cis rs7592578 0.679 rs62181019 chr2:191325414 A/G cg10560079 chr2:191398806 TMEM194B -0.77 -11.2 -0.52 5.09e-25 Diastolic blood pressure; LIHC cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg18357526 chr6:26021779 HIST1H4A 0.81 10.96 0.51 3.72e-24 Intelligence (multi-trait analysis); LIHC cis rs963731 0.579 rs6739568 chr2:39287550 G/T cg04010122 chr2:39346883 SOS1 -0.68 -6.16 -0.32 2.07e-9 Corticobasal degeneration; LIHC cis rs3008870 1.000 rs2755248 chr1:67492624 A/G cg02640540 chr1:67518911 SLC35D1 0.45 6.19 0.32 1.69e-9 Lymphocyte percentage of white cells; LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg17512779 chr8:17104072 CNOT7;VPS37A -0.61 -6.39 -0.33 5.27e-10 Liver enzyme levels (alkaline phosphatase); LIHC cis rs67311347 1.000 rs9834052 chr3:40399060 G/A cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.46e-9 Renal cell carcinoma; LIHC cis rs6840360 0.615 rs62329085 chr4:152470237 G/A cg22705602 chr4:152727874 NA -0.32 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs7209700 0.614 rs7225927 chr17:45323934 A/G cg18085866 chr17:45331354 ITGB3 -0.4 -5.83 -0.3 1.27e-8 IgG glycosylation; LIHC cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg03060546 chr3:49711283 APEH 0.4 6.03 0.31 4.2e-9 Menarche (age at onset); LIHC trans rs7618501 0.633 rs2856234 chr3:50139142 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.57 -9.28 -0.45 1.92e-18 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21099776 chr17:17739742 SREBF1 0.47 6.33 0.32 7.51e-10 Lung function (FEV1/FVC); LIHC cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg23806715 chr17:73775811 H3F3B 0.7 6.78 0.34 5.45e-11 Psoriasis; LIHC cis rs9291683 0.632 rs10939669 chr4:10045827 A/G cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.56e-13 Bone mineral density; LIHC cis rs9486715 0.793 rs2499777 chr6:97013814 T/C cg18709589 chr6:96969512 KIAA0776 -0.33 -5.81 -0.3 1.4e-8 Headache; LIHC cis rs881375 0.967 rs1014529 chr9:123684943 C/G cg14580859 chr9:123691850 NA 0.4 6.82 0.35 4.24e-11 Rheumatoid arthritis; LIHC cis rs10206020 0.836 rs10202105 chr2:1553301 C/T cg01028140 chr2:1542097 TPO -0.44 -6.99 -0.35 1.46e-11 IgG glycosylation; LIHC cis rs28647808 0.618 rs7025970 chr9:136267173 G/A cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs1461503 0.966 rs10790547 chr11:122842110 T/A cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs7124681 0.585 rs10838773 chr11:47834346 G/A cg20307385 chr11:47447363 PSMC3 0.76 11.45 0.53 6.58e-26 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs722599 0.639 rs2193596 chr14:75234101 A/C cg08847533 chr14:75593920 NEK9 0.48 7.0 0.35 1.32e-11 IgG glycosylation; LIHC cis rs1355223 0.902 rs1773908 chr11:34743380 A/G cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1712517 0.771 rs2008530 chr10:105058839 G/A cg05636881 chr10:105038444 INA 0.46 7.12 0.36 6.56e-12 Migraine; LIHC cis rs9309711 0.666 rs4321399 chr2:3481659 G/A cg15506890 chr2:3487001 NA -0.43 -6.88 -0.35 2.93e-11 Neurofibrillary tangles; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01711272 chr12:56122120 CD63 -0.4 -6.54 -0.33 2.26e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs992157 0.835 rs4674283 chr2:219144254 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.12 -0.55 2.19e-28 Colorectal cancer; LIHC cis rs10870270 0.956 rs10430618 chr10:133748996 C/T cg26149184 chr10:133730230 NA 0.46 7.21 0.36 3.71e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs60871478 1.000 rs7795258 chr7:795227 A/G cg04727924 chr7:799746 HEATR2 -0.58 -8.84 -0.43 5.02e-17 Cerebrospinal P-tau181p levels; LIHC cis rs60871478 1.000 rs34761279 chr7:794471 A/G cg13301601 chr7:774633 HEATR2 -0.41 -5.86 -0.3 1.07e-8 Cerebrospinal P-tau181p levels; LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg11494091 chr17:61959527 GH2 0.45 8.32 0.41 2.12e-15 Prudent dietary pattern; LIHC cis rs12365397 0.748 rs1845821 chr11:43258997 T/C cg16667275 chr11:43333495 API5 0.4 5.95 0.31 6.63e-9 Migraine; LIHC trans rs7613875 0.600 rs2624848 chr3:50165101 T/C cg21659725 chr3:3221576 CRBN -0.6 -9.07 -0.44 9.59e-18 Body mass index; LIHC cis rs8072100 0.875 rs4794047 chr17:45763005 A/T cg08085267 chr17:45401833 C17orf57 0.53 7.72 0.39 1.26e-13 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2574704 0.851 rs2574723 chr3:11659592 C/T cg15876825 chr3:11651881 VGLL4 0.49 7.9 0.39 3.94e-14 Body mass index; LIHC cis rs798554 0.959 rs798558 chr7:2758935 T/G cg13628971 chr7:2884303 GNA12 0.48 6.88 0.35 2.89e-11 Height; LIHC cis rs6429082 0.509 rs2803846 chr1:235521054 C/G cg26050004 chr1:235667680 B3GALNT2 0.41 6.17 0.32 1.89e-9 Adiposity; LIHC cis rs743757 1.000 rs2236979 chr3:50486895 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.49 7.73 0.39 1.25e-13 Diastolic blood pressure; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs7412746 0.622 rs72704654 chr1:150826410 G/A cg17724175 chr1:150552817 MCL1 0.47 9.08 0.44 9.03e-18 Melanoma; LIHC cis rs8103278 0.740 rs2341097 chr19:46268902 C/T cg14061069 chr19:46274453 DMPK -0.55 -8.49 -0.42 6.37e-16 Coronary artery disease; LIHC trans rs2073499 0.935 rs2526396 chr3:50188309 C/T cg21659725 chr3:3221576 CRBN 0.6 6.38 0.33 5.71e-10 Schizophrenia; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg07725925 chr16:89976287 TCF25 0.43 5.95 0.31 6.58e-9 Skin colour saturation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26576155 chr15:85201829 NMB 0.47 6.26 0.32 1.17e-9 Lung function (FEV1/FVC); LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.5 7.12 0.36 6.28e-12 Height; LIHC cis rs67478160 0.584 rs2295148 chr14:104195610 T/C cg08213375 chr14:104286397 PPP1R13B 0.48 9.16 0.44 5.06e-18 Schizophrenia; LIHC cis rs9420 0.961 rs576859 chr11:57480623 A/C cg19752551 chr11:57585705 CTNND1 0.5 7.14 0.36 5.79e-12 Schizophrenia; LIHC cis rs2235642 0.601 rs2235647 chr16:1601331 C/A cg03034668 chr16:1723424 CRAMP1L -0.36 -6.11 -0.31 2.75e-9 Coronary artery disease; LIHC cis rs12477438 0.798 rs13393860 chr2:99590397 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.02 -0.51 2.28e-24 Chronic sinus infection; LIHC cis rs116095464 0.681 rs9687745 chr5:229309 C/T cg22496380 chr5:211416 CCDC127 -0.99 -10.26 -0.49 1.02e-21 Breast cancer; LIHC cis rs4853012 0.838 rs59570457 chr2:74344282 T/C cg20011983 chr2:74347215 NA -0.39 -5.77 -0.3 1.79e-8 Gestational age at birth (maternal effect); LIHC cis rs34779708 0.931 rs2148482 chr10:35348910 A/G cg03585969 chr10:35415529 CREM 0.87 13.22 0.58 1.6e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2839186 0.739 rs7282763 chr21:47696800 C/T cg05896524 chr21:47604654 C21orf56 0.44 6.61 0.34 1.49e-10 Testicular germ cell tumor; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg11062466 chr8:58055876 NA 0.54 7.69 0.38 1.54e-13 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.863 rs10034450 chr4:120455649 A/G cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs10463316 0.894 rs954339 chr5:150752161 C/A cg03212797 chr5:150827313 SLC36A1 -0.42 -6.26 -0.32 1.18e-9 Metabolite levels (Pyroglutamine); LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg02782426 chr3:40428986 ENTPD3 0.33 6.17 0.32 1.94e-9 Renal cell carcinoma; LIHC cis rs9611565 0.921 rs5751080 chr22:41736267 A/G cg03806693 chr22:41940476 POLR3H -0.47 -6.23 -0.32 1.37e-9 Vitiligo; LIHC cis rs7020830 0.898 rs12554874 chr9:37073902 C/T cg14294708 chr9:37120828 ZCCHC7 1.13 23.94 0.79 4.53e-75 Schizophrenia; LIHC cis rs4319547 0.661 rs7398014 chr12:122943980 T/C cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.97 -0.4 2.43e-14 Body mass index; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.96 20.68 0.75 3.41e-62 Prudent dietary pattern; LIHC cis rs11724804 0.532 rs62297079 chr4:879977 G/A cg20814179 chr4:940893 TMEM175 0.43 6.04 0.31 3.98e-9 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs5753037 0.543 rs140126 chr22:30147038 A/G cg01021169 chr22:30184971 ASCC2 -0.32 -6.05 -0.31 3.79e-9 Type 1 diabetes; LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg03721293 chr16:90014378 DEF8 0.42 6.98 0.35 1.5e-11 Skin colour saturation; LIHC cis rs2455799 0.613 rs13060772 chr3:15896795 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.96e-13 Mean platelet volume; LIHC cis rs7829975 0.806 rs2428 chr8:8641145 C/T cg06636001 chr8:8085503 FLJ10661 0.45 7.37 0.37 1.29e-12 Mood instability; LIHC cis rs2404602 0.669 rs12595313 chr15:76978370 A/G cg03037974 chr15:76606532 NA 0.74 14.57 0.62 9.41e-38 Blood metabolite levels; LIHC cis rs7258465 1.000 rs10413237 chr19:18548249 A/C cg10790698 chr19:18539756 SSBP4 -0.35 -7.08 -0.36 8.3e-12 Breast cancer; LIHC cis rs9902453 0.904 rs7225686 chr17:28356744 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs10911232 0.507 rs3934579 chr1:183027432 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.55 0.5 1e-22 Hypertriglyceridemia; LIHC cis rs3857067 0.806 rs7654919 chr4:95136164 C/T cg11021082 chr4:95130006 SMARCAD1 -0.41 -7.43 -0.37 8.63e-13 QT interval; LIHC cis rs2980439 0.556 rs2921059 chr8:8317887 G/T cg08975724 chr8:8085496 FLJ10661 0.55 8.7 0.43 1.43e-16 Neuroticism; LIHC cis rs12477438 0.765 rs7605218 chr2:99593080 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.41 -0.49 3.08e-22 Chronic sinus infection; LIHC cis rs2075371 0.933 rs1901214 chr7:133945108 C/T cg20476274 chr7:133979776 SLC35B4 -0.7 -11.31 -0.52 2e-25 Mean platelet volume; LIHC cis rs7914558 0.621 rs12219346 chr10:104657300 T/C cg15744005 chr10:104629667 AS3MT -0.35 -7.38 -0.37 1.22e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01717636 chr1:46216399 IPP -0.56 -6.69 -0.34 9.19e-11 Systolic blood pressure; LIHC cis rs854765 0.619 rs1101727 chr17:18016148 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.36 6.78 0.34 5.16e-11 Total body bone mineral density; LIHC cis rs11792861 0.816 rs11788336 chr9:111688387 T/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.93 -0.35 2.07e-11 Menarche (age at onset); LIHC cis rs7772486 0.790 rs1854900 chr6:146331382 G/A cg23711669 chr6:146136114 FBXO30 0.67 11.94 0.54 1.02e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs2842992 0.724 rs15982 chr6:160199687 T/C cg16489826 chr6:160211363 TCP1;MRPL18 0.48 8.8 0.43 6.96e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs9818758 0.607 rs11706052 chr3:49064110 A/G cg07636037 chr3:49044803 WDR6 -0.84 -8.52 -0.42 5.33e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs734999 0.545 rs28532547 chr1:2561286 T/G cg18854424 chr1:2615690 NA -0.33 -7.2 -0.36 3.87e-12 Ulcerative colitis; LIHC cis rs6430585 0.583 rs2322813 chr2:136582809 A/G cg15123519 chr2:136567270 LCT -0.4 -6.0 -0.31 4.93e-9 Corneal structure; LIHC cis rs11888559 0.655 rs7601146 chr2:203950592 G/A cg24605529 chr2:203879461 NBEAL1 0.75 5.78 0.3 1.66e-8 Height; LIHC cis rs1976403 0.659 rs10799700 chr1:21820968 G/C cg20417195 chr1:21767127 NBPF3 0.38 5.89 0.3 9.28e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs600626 0.588 rs72997616 chr11:75474195 C/A cg24262691 chr11:75473276 NA 0.4 5.89 0.3 9.02e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs1707322 1.000 rs11211235 chr1:46440375 G/A cg06784218 chr1:46089804 CCDC17 0.36 6.55 0.33 2.13e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg19318889 chr4:1322082 MAEA 0.4 5.77 0.3 1.81e-8 Obesity-related traits; LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.59 11.73 0.54 5.98e-27 Prudent dietary pattern; LIHC cis rs2777491 0.957 rs8027626 chr15:41711514 T/G cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.21 -0.45 3.37e-18 Ulcerative colitis; LIHC trans rs6489882 0.867 rs2384073 chr12:113367595 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs11122272 0.766 rs2790867 chr1:231548059 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.7 11.15 0.52 7.49e-25 Hemoglobin concentration; LIHC cis rs7224685 0.569 rs12947597 chr17:3999199 A/G cg09695851 chr17:3907499 NA -0.49 -6.34 -0.32 7.41e-10 Type 2 diabetes; LIHC trans rs11098499 0.863 rs3775858 chr4:120486028 A/G cg25214090 chr10:38739885 LOC399744 0.57 8.97 0.44 2.03e-17 Corneal astigmatism; LIHC cis rs1538970 0.924 rs7528573 chr1:45913860 T/C cg24296786 chr1:45957014 TESK2 -0.51 -7.31 -0.37 1.9e-12 Platelet count; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg20102877 chr2:27665638 KRTCAP3 -0.41 -5.72 -0.3 2.27e-8 Total body bone mineral density; LIHC cis rs2857078 0.720 rs9901595 chr17:42305699 G/A cg19774624 chr17:42201019 HDAC5 -0.56 -7.86 -0.39 5.08e-14 Red cell distribution width;Reticulocyte count; LIHC cis rs6754311 0.593 rs1438305 chr2:136502792 C/G cg25344623 chr2:136566232 LCT 0.44 8.85 0.43 4.78e-17 Mosquito bite size; LIHC cis rs7937890 1.000 rs2970335 chr11:14325401 A/C cg02886208 chr11:14281011 SPON1 -0.55 -8.15 -0.4 6.81e-15 Mitochondrial DNA levels; LIHC cis rs5753618 0.561 rs9609264 chr22:31746719 C/G cg07713946 chr22:31675144 LIMK2 0.42 7.59 0.38 3.03e-13 Colorectal cancer; LIHC cis rs919433 0.963 rs12693815 chr2:198168403 T/C cg10820045 chr2:198174542 NA -0.57 -9.61 -0.46 1.64e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs62229266 0.626 rs7280896 chr21:37460906 G/A cg12218747 chr21:37451666 NA -0.41 -6.64 -0.34 1.24e-10 Mitral valve prolapse; LIHC cis rs6942756 0.806 rs9641846 chr7:128873679 G/A cg02491457 chr7:128862824 NA 0.64 10.25 0.48 1.15e-21 White matter hyperintensity burden; LIHC cis rs9534288 0.913 rs9534298 chr13:46625566 C/G cg15192986 chr13:46630673 CPB2 -0.58 -8.63 -0.42 2.29e-16 Blood protein levels; LIHC cis rs9790314 0.696 rs9290069 chr3:160890946 A/G cg03342759 chr3:160939853 NMD3 -0.78 -11.4 -0.52 9.78e-26 Morning vs. evening chronotype; LIHC cis rs2279817 0.820 rs924686 chr1:18027726 C/A cg21791023 chr1:18019539 ARHGEF10L 0.41 6.24 0.32 1.33e-9 Neuroticism; LIHC cis rs11673344 0.832 rs11084871 chr19:37532925 G/A cg27390819 chr19:37464633 NA -0.51 -6.16 -0.32 2.02e-9 Obesity-related traits; LIHC cis rs250677 0.687 rs185155 chr5:148455893 T/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC cis rs875971 0.545 rs73142245 chr7:65691649 A/G cg11764359 chr7:65958608 NA 0.5 6.91 0.35 2.37e-11 Aortic root size; LIHC cis rs4803468 0.967 rs3826713 chr19:41892269 C/T cg14132834 chr19:41945861 ATP5SL -0.4 -5.82 -0.3 1.36e-8 Height; LIHC cis rs6596100 0.538 rs17166268 chr5:132180990 C/T cg02081065 chr5:132209139 LEAP2 -0.26 -5.94 -0.31 7.17e-9 Breast cancer; LIHC cis rs6750047 0.549 rs151096 chr2:38316571 A/C cg19753864 chr2:38320028 NA -0.34 -6.06 -0.31 3.6e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs3796352 1.000 rs11710707 chr3:52975916 A/G cg04865290 chr3:52927548 TMEM110 -0.51 -5.89 -0.3 9.01e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs6963495 0.799 rs73190201 chr7:105165891 A/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs1707322 0.716 rs10890342 chr1:46157087 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.26 0.37 2.63e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6951245 0.580 rs10257426 chr7:1213694 G/A cg23978390 chr7:1156363 C7orf50 0.59 6.88 0.35 2.88e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7903847 0.642 rs12258560 chr10:99137048 T/C cg20016023 chr10:99160130 RRP12 -0.41 -6.43 -0.33 4.28e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg18404041 chr3:52824283 ITIH1 -0.51 -8.62 -0.42 2.48e-16 Bipolar disorder; LIHC cis rs12220238 1.000 rs11000912 chr10:75948477 A/C cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.27 0.32 1.1e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg03806693 chr22:41940476 POLR3H 0.98 10.53 0.49 1.23e-22 Vitiligo; LIHC cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg03452623 chr4:187889614 NA -0.32 -8.03 -0.4 1.54e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.12 11.68 0.53 9.41e-27 Platelet count; LIHC cis rs17106184 1.000 rs12065210 chr1:50942784 C/T cg07174182 chr1:51127561 FAF1 -0.57 -6.55 -0.33 2.09e-10 Type 2 diabetes; LIHC cis rs2404602 0.692 rs12911174 chr15:77149943 G/A cg23625390 chr15:77176239 SCAPER 0.36 5.84 0.3 1.2e-8 Blood metabolite levels; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg06138931 chr13:21896616 NA 0.49 8.42 0.41 1.03e-15 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6964587 0.692 rs4729018 chr7:91644613 C/T cg17063962 chr7:91808500 NA 0.63 11.29 0.52 2.48e-25 Breast cancer; LIHC cis rs11122272 0.735 rs2486741 chr1:231516450 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs9646954 0.542 rs4149505 chr2:101033697 G/A cg14675211 chr2:100938903 LONRF2 0.5 7.73 0.39 1.22e-13 Intelligence (multi-trait analysis); LIHC trans rs6952808 0.858 rs12671113 chr7:1965255 G/A cg04565464 chr8:145669602 NFKBIL2 0.39 6.22 0.32 1.42e-9 Bipolar disorder and schizophrenia; LIHC cis rs61990749 0.597 rs117131659 chr14:78131126 C/T cg21497246 chr14:78225524 SNW1;C14orf178 0.44 6.74 0.34 6.66e-11 Fibroblast growth factor basic levels; LIHC cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg06466757 chr4:1255808 NA 0.35 5.78 0.3 1.64e-8 Obesity-related traits; LIHC cis rs7131987 0.650 rs6487808 chr12:29463359 C/T cg16970926 chr12:29381810 FAR2 -0.28 -6.02 -0.31 4.57e-9 QT interval; LIHC cis rs1538970 1.000 rs9326141 chr1:45828943 A/G cg05343316 chr1:45956843 TESK2 -0.62 -9.22 -0.45 3.05e-18 Platelet count; LIHC cis rs6967414 0.786 rs9639026 chr7:6746736 A/G cg00387323 chr7:6746715 ZNF12 0.65 7.29 0.37 2.2e-12 Hematocrit;Hemoglobin concentration; LIHC cis rs7647973 0.554 rs13096480 chr3:49658084 A/G cg03060546 chr3:49711283 APEH 0.59 6.78 0.34 5.41e-11 Menarche (age at onset); LIHC cis rs7572733 0.534 rs58374969 chr2:198764363 C/T cg10820045 chr2:198174542 NA 0.49 7.26 0.37 2.57e-12 Dermatomyositis; LIHC cis rs7552404 0.727 rs7547056 chr1:76279267 C/T cg03433033 chr1:76189801 ACADM 0.59 7.51 0.38 5.35e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg04267008 chr7:1944627 MAD1L1 -0.68 -10.45 -0.49 2.29e-22 Bipolar disorder and schizophrenia; LIHC cis rs8114671 0.836 rs6120778 chr20:33565169 T/C cg07148914 chr20:33460835 GGT7 0.6 9.22 0.45 3.01e-18 Height; LIHC cis rs6840360 1.000 rs6823002 chr4:152604467 T/G cg22705602 chr4:152727874 NA -0.3 -6.12 -0.31 2.51e-9 Intelligence (multi-trait analysis); LIHC cis rs7408868 1.000 rs10410514 chr19:15277610 C/T cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.68e-8 Pulse pressure; LIHC cis rs1941023 0.584 rs2233252 chr11:60157107 T/G cg08716584 chr11:60157161 MS4A7 -0.36 -8.26 -0.41 3.34e-15 Congenital heart disease (maternal effect); LIHC cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 12.2 0.55 1.19e-28 Platelet count; LIHC cis rs5769707 0.967 rs5770585 chr22:50007874 G/A cg01652190 chr22:50026171 C22orf34 -0.3 -6.98 -0.35 1.53e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs8141529 0.748 rs132529 chr22:29296652 A/G cg02153584 chr22:29168773 CCDC117 -0.5 -7.65 -0.38 2e-13 Lymphocyte counts; LIHC cis rs9811920 0.541 rs1016914 chr3:99640121 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs600806 0.778 rs891379 chr1:110003605 A/G cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.16 -0.32 2.08e-9 Intelligence (multi-trait analysis); LIHC cis rs600806 0.778 rs10857787 chr1:110010289 C/T cg23091122 chr1:110024289 SYPL2 -0.48 -6.67 -0.34 1.04e-10 Intelligence (multi-trait analysis); LIHC cis rs908922 0.651 rs1988805 chr1:152531495 T/G cg20991723 chr1:152506922 NA 0.53 8.76 0.43 9.49e-17 Hair morphology; LIHC cis rs6570726 0.791 rs9373463 chr6:145894762 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.14 0.31 2.35e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7122539 0.646 rs543191 chr11:66583779 T/G cg24851651 chr11:66362959 CCS 0.38 6.66 0.34 1.11e-10 HIV-1 susceptibility; LIHC cis rs12497850 0.864 rs12493001 chr3:49181885 A/G cg06212747 chr3:49208901 KLHDC8B 0.6 7.87 0.39 4.78e-14 Parkinson's disease; LIHC cis rs35306767 0.903 rs12249634 chr10:872744 G/A cg20503657 chr10:835505 NA 1.01 11.16 0.52 7.11e-25 Eosinophil percentage of granulocytes; LIHC cis rs9513627 0.833 rs112671387 chr13:100123073 A/G cg25919922 chr13:100150906 NA -0.79 -6.95 -0.35 1.86e-11 Obesity-related traits; LIHC cis rs4917300 0.650 rs4917218 chr8:143072470 G/A cg06573787 chr8:143070187 NA 0.28 5.82 0.3 1.38e-8 Amyotrophic lateral sclerosis; LIHC cis rs7666738 0.606 rs6852813 chr4:99084671 G/A cg05340658 chr4:99064831 C4orf37 0.65 11.68 0.53 9.06e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7520050 0.966 rs7522601 chr1:46419021 G/A cg03146154 chr1:46216737 IPP -0.38 -6.29 -0.32 9.84e-10 Red blood cell count;Reticulocyte count; LIHC cis rs1823913 1.000 rs1454749 chr2:192105635 C/T cg12404831 chr2:192114017 MYO1B 0.34 6.7 0.34 8.82e-11 Obesity-related traits; LIHC cis rs7617773 0.784 rs11715799 chr3:48255220 A/G cg11946769 chr3:48343235 NME6 0.89 10.97 0.51 3.51e-24 Coronary artery disease; LIHC cis rs611744 0.870 rs423940 chr8:109093578 C/T cg21045802 chr8:109455806 TTC35 0.51 8.52 0.42 5e-16 Dupuytren's disease; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg11060661 chr22:24314208 DDT;DDTL 0.63 10.73 0.5 2.46e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1005277 0.563 rs2505215 chr10:38481273 A/G cg25427524 chr10:38739819 LOC399744 -0.72 -14.26 -0.61 1.58e-36 Extrinsic epigenetic age acceleration; LIHC cis rs4689388 0.926 rs5018648 chr4:6292818 C/G cg14416269 chr4:6271139 WFS1 -0.44 -6.11 -0.31 2.65e-9 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg12310025 chr6:25882481 NA 0.65 8.21 0.41 4.69e-15 Intelligence (multi-trait analysis); LIHC cis rs9733 0.519 rs12095002 chr1:150649249 G/A cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Tonsillectomy; LIHC cis rs35306767 0.953 rs7908138 chr10:962978 C/T cg20503657 chr10:835505 NA 0.9 10.77 0.5 1.76e-23 Eosinophil percentage of granulocytes; LIHC cis rs9649465 1.000 rs1506635 chr7:123317184 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.02e-15 Migraine; LIHC cis rs748404 0.587 rs690276 chr15:43704558 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.48 7.44 0.37 8.27e-13 Lung cancer; LIHC cis rs796364 0.806 rs79725795 chr2:201083534 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.64 -6.86 -0.35 3.26e-11 Schizophrenia; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg16132339 chr22:24313637 DDTL;DDT 0.74 14.48 0.62 2.09e-37 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs992157 0.835 rs4674283 chr2:219144254 G/A cg00012203 chr2:219082015 ARPC2 -0.82 -13.08 -0.58 5.58e-32 Colorectal cancer; LIHC cis rs1707322 1.000 rs785510 chr1:46528618 T/C cg03146154 chr1:46216737 IPP -0.46 -7.1 -0.36 7.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11871801 0.517 rs645692 chr17:40701073 C/T cg14558262 chr17:40713999 COASY 0.62 9.51 0.46 3.55e-19 Crohn's disease; LIHC cis rs151997 0.925 rs27260 chr5:50166696 C/T cg06027927 chr5:50259733 NA 0.57 7.57 0.38 3.47e-13 Callous-unemotional behaviour; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08251337 chr16:81040389 C16orf61;CENPN -0.5 -6.77 -0.34 5.69e-11 Systolic blood pressure; LIHC cis rs11792861 0.888 rs11794648 chr9:111829792 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.82 0.43 6.15e-17 Menarche (age at onset); LIHC cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs507080 0.961 rs543327 chr11:118549985 G/T cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC cis rs9916302 0.706 rs582176 chr17:37453999 T/C cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs12579753 0.879 rs11615729 chr12:82128318 T/A cg07988820 chr12:82153109 PPFIA2 -0.49 -6.16 -0.32 2.04e-9 Resting heart rate; LIHC cis rs12291225 0.645 rs3763950 chr11:14278049 T/A cg19336497 chr11:14380999 RRAS2 -0.64 -12.71 -0.57 1.42e-30 Sense of smell; LIHC trans rs6600671 1.000 rs10794671 chr1:121168242 A/C cg09829573 chr1:144692074 NBPF9 -0.42 -7.64 -0.38 2.17e-13 Hip geometry; LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg02782426 chr3:40428986 ENTPD3 -0.34 -6.29 -0.32 9.67e-10 Renal cell carcinoma; LIHC cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg10896456 chr17:42255109 ASB16;C17orf65 0.55 10.3 0.49 7.74e-22 Total body bone mineral density; LIHC cis rs644799 0.932 rs572015 chr11:95637416 T/A cg25478527 chr11:95522999 CEP57;FAM76B 0.43 5.87 0.3 1.02e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4654899 0.758 rs6658679 chr1:21376451 T/C cg08539965 chr1:21396338 EIF4G3 0.33 5.83 0.3 1.31e-8 Superior frontal gyrus grey matter volume; LIHC cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg11502198 chr6:26597334 ABT1 0.6 9.17 0.44 4.62e-18 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.673 rs9895815 chr17:29138033 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg07450219 chr17:78428858 NA -0.43 -6.36 -0.33 6.29e-10 Alopecia areata; LIHC trans rs208520 0.661 rs7740835 chr6:66865548 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.23 -0.41 3.95e-15 Exhaled nitric oxide output; LIHC cis rs919433 0.963 rs13033821 chr2:198173536 T/G cg10820045 chr2:198174542 NA -0.58 -9.64 -0.46 1.29e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg00149659 chr3:10157352 C3orf10 0.69 7.22 0.36 3.4e-12 Alzheimer's disease; LIHC cis rs9733 0.628 rs11807409 chr1:150683423 C/T cg17724175 chr1:150552817 MCL1 0.48 9.65 0.46 1.21e-19 Tonsillectomy; LIHC cis rs2832191 0.740 rs2853830 chr21:30416824 A/G cg08807101 chr21:30365312 RNF160 0.79 12.06 0.55 3.92e-28 Dental caries; LIHC cis rs4423214 1.000 rs12789751 chr11:71164471 G/A cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs782590 0.694 rs2627775 chr2:55877113 C/T cg18811423 chr2:55921094 PNPT1 0.89 13.12 0.58 3.95e-32 Metabolic syndrome; LIHC cis rs9419702 0.568 rs10782366 chr10:133557866 G/A cg20568497 chr10:133558893 NA 0.45 6.98 0.35 1.52e-11 Survival in rectal cancer; LIHC cis rs7312933 0.701 rs10880260 chr12:42561398 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 8.01 0.4 1.79e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg19443418 chr4:39482010 LOC401127 0.41 6.83 0.35 3.94e-11 Bilirubin levels; LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.92 9.02 0.44 1.42e-17 Platelet count; LIHC cis rs1799949 1.000 rs4793229 chr17:41418334 C/T cg05368731 chr17:41323189 NBR1 -0.71 -12.13 -0.55 2.03e-28 Menopause (age at onset); LIHC cis rs6088580 0.609 rs6059845 chr20:33036500 G/A cg08999081 chr20:33150536 PIGU 0.66 13.13 0.58 3.67e-32 Glomerular filtration rate (creatinine); LIHC cis rs950169 0.922 rs11638445 chr15:85137694 C/A cg12863693 chr15:85201151 NMB 0.44 5.87 0.3 1.02e-8 Schizophrenia; LIHC trans rs2262909 0.962 rs55735642 chr19:22241176 C/T cg05197062 chr11:11642011 GALNTL4 0.42 6.08 0.31 3.17e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs6963495 0.818 rs73192120 chr7:105171156 C/T cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs782590 0.764 rs2054728 chr2:55818419 C/T cg18811423 chr2:55921094 PNPT1 0.78 11.57 0.53 2.42e-26 Metabolic syndrome; LIHC cis rs36207871 1 rs36207871 chr12:56684496 TAGGAA/T cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Inflammatory skin disease; LIHC cis rs8049040 0.609 rs7188858 chr16:71468895 T/C cg06353428 chr16:71660113 MARVELD3 -0.67 -7.06 -0.36 9.54e-12 Blood protein levels; LIHC cis rs7116495 1.000 rs482013 chr11:71803962 G/A cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC trans rs8073060 0.586 rs225278 chr17:33974170 C/T cg19694781 chr19:47549865 TMEM160 -1.26 -13.75 -0.6 1.51e-34 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs4722166 1.000 rs4722166 chr7:22738762 G/T cg05472934 chr7:22766657 IL6 0.48 6.91 0.35 2.35e-11 Lung cancer; LIHC cis rs10861342 1.000 rs10861342 chr12:105458797 C/T cg23923672 chr12:105501055 KIAA1033 -0.67 -7.66 -0.38 1.98e-13 IgG glycosylation; LIHC cis rs2153535 0.580 rs1932281 chr6:8473765 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs12188164 0.543 rs7728027 chr5:459943 T/C cg16584290 chr5:462447 EXOC3 0.37 6.03 0.31 4.14e-9 Cystic fibrosis severity; LIHC trans rs1814175 0.592 rs1794161 chr11:49898825 A/C cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs7640424 0.826 rs7635063 chr3:107818777 C/T cg09227934 chr3:107805635 CD47 -0.5 -6.28 -0.32 1.05e-9 Body mass index; LIHC cis rs9733 0.650 rs61820165 chr1:150555987 C/T cg18016565 chr1:150552671 MCL1 -0.54 -10.95 -0.51 3.98e-24 Tonsillectomy; LIHC cis rs867186 0.541 rs77173268 chr20:33288002 G/A cg08999081 chr20:33150536 PIGU 0.57 5.95 0.31 6.59e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs10508774 1.000 rs11008974 chr10:32844014 A/G cg01819863 chr10:32635814 EPC1 0.65 6.1 0.31 2.87e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg11494091 chr17:61959527 GH2 0.44 8.14 0.4 7.19e-15 Prudent dietary pattern; LIHC cis rs4319547 0.956 rs10744275 chr12:123048618 A/G cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.15 -0.4 6.97e-15 Body mass index; LIHC cis rs11098499 0.754 rs7672372 chr4:120248406 A/G cg09307838 chr4:120376055 NA 0.71 11.16 0.52 6.98e-25 Corneal astigmatism; LIHC cis rs2204008 0.774 rs7959048 chr12:37948276 T/A cg26384229 chr12:38710491 ALG10B 0.82 10.25 0.48 1.14e-21 Bladder cancer; LIHC cis rs2073499 1.000 rs10510755 chr3:50281168 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.66 6.96 0.35 1.72e-11 Schizophrenia; LIHC cis rs16854884 0.586 rs6782789 chr3:143746691 G/A cg06585982 chr3:143692056 C3orf58 0.58 7.56 0.38 3.77e-13 Economic and political preferences (feminism/equality); LIHC trans rs208520 0.874 rs208491 chr6:66928459 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.24 -0.41 3.72e-15 Exhaled nitric oxide output; LIHC cis rs7224685 0.569 rs12942513 chr17:4016721 C/A cg09695851 chr17:3907499 NA 0.6 6.81 0.35 4.42e-11 Type 2 diabetes; LIHC cis rs9790314 1.000 rs3849524 chr3:161015589 C/T cg04691961 chr3:161091175 C3orf57 -0.42 -6.82 -0.35 4.09e-11 Morning vs. evening chronotype; LIHC cis rs7917772 0.503 rs11191328 chr10:104305185 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.84 0.57 4.73e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7980687 0.628 rs1609520 chr12:123735937 A/G cg00376283 chr12:123451042 ABCB9 -0.63 -9.6 -0.46 1.79e-19 Height;Educational attainment;Head circumference (infant); LIHC cis rs2180341 0.814 rs6940933 chr6:127732740 C/G cg24812749 chr6:127587940 RNF146 0.78 12.1 0.55 2.78e-28 Breast cancer; LIHC cis rs6918586 0.658 rs198803 chr6:26135052 T/A cg18357526 chr6:26021779 HIST1H4A -0.58 -8.72 -0.43 1.22e-16 Schizophrenia; LIHC cis rs4819052 0.851 rs7281263 chr21:46695606 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 11.83 0.54 2.59e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8180040 0.691 rs12489211 chr3:47221451 T/A cg16586182 chr3:47516702 SCAP -0.5 -9.02 -0.44 1.4e-17 Colorectal cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg22658129 chr5:49962507 PARP8 0.51 6.59 0.34 1.64e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2073300 0.609 rs6132615 chr20:23413200 T/C cg16736954 chr20:23401023 NAPB 0.7 8.08 0.4 1.15e-14 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11719291 0.915 rs9834996 chr3:48754877 G/T cg07636037 chr3:49044803 WDR6 -0.73 -7.5 -0.38 5.68e-13 Cognitive function; LIHC cis rs34540877 1.000 rs71351186 chr19:33164583 C/T cg22980127 chr19:33182716 NUDT19 0.9 6.19 0.32 1.72e-9 Red cell distribution width; LIHC trans rs9531686 0.967 rs7994341 chr13:85546229 T/G cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.25 0.32 1.24e-9 Anorexia nervosa; LIHC cis rs4819052 0.724 rs1304487 chr21:46657283 C/G cg22633049 chr21:46681294 NA 0.33 5.92 0.3 8e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2404602 0.647 rs11072628 chr15:77107761 C/A cg23625390 chr15:77176239 SCAPER -0.53 -8.84 -0.43 5.07e-17 Blood metabolite levels; LIHC cis rs7772486 0.720 rs702320 chr6:146006654 G/A cg23711669 chr6:146136114 FBXO30 -0.74 -13.4 -0.59 3.3e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs7027203 0.828 rs10761287 chr9:96609150 A/G cg14598338 chr9:96623480 NA -0.33 -6.54 -0.33 2.19e-10 DNA methylation (variation); LIHC cis rs1801251 1.000 rs12990821 chr2:233617585 C/G cg25237894 chr2:233734115 C2orf82 0.58 11.22 0.52 4.27e-25 Coronary artery disease; LIHC cis rs992157 0.835 rs7585702 chr2:219146607 T/C cg00012203 chr2:219082015 ARPC2 -0.82 -13.06 -0.58 6.88e-32 Colorectal cancer; LIHC cis rs12980942 0.591 rs11879435 chr19:41757603 C/T cg25627403 chr19:41769009 HNRNPUL1 0.58 6.96 0.35 1.72e-11 Coronary artery disease; LIHC cis rs7703744 0.747 rs6896277 chr5:118678721 C/T cg10911160 chr5:118691794 TNFAIP8 -0.49 -5.79 -0.3 1.56e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9916302 0.904 rs10852933 chr17:37698194 G/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.13 -0.58 3.45e-32 Glomerular filtration rate (creatinine); LIHC cis rs17270561 0.887 rs717551 chr6:25855624 T/C cg16482183 chr6:26056742 HIST1H1C 0.59 6.8 0.34 4.76e-11 Iron status biomarkers; LIHC cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg09323728 chr8:95962352 TP53INP1 -0.28 -6.06 -0.31 3.54e-9 Type 2 diabetes; LIHC cis rs116095464 0.558 rs60251075 chr5:245292 T/C cg22857025 chr5:266934 NA -1.48 -18.17 -0.7 4.09e-52 Breast cancer; LIHC cis rs2204008 0.748 rs11180579 chr12:38237830 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.78 0.5 1.62e-23 Bladder cancer; LIHC cis rs2153535 0.542 rs915354 chr6:8440357 T/C cg21535247 chr6:8435926 SLC35B3 0.61 7.89 0.39 4.23e-14 Motion sickness; LIHC cis rs739401 0.611 rs12284275 chr11:3024384 T/C cg20651018 chr11:3035856 CARS -0.35 -5.96 -0.31 6.34e-9 Longevity; LIHC cis rs875971 0.862 rs4149461 chr7:65744732 T/C cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs6504950 0.566 rs12937360 chr17:53046298 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.59 8.61 0.42 2.64e-16 Breast cancer; LIHC cis rs7818688 0.697 rs77402106 chr8:95970484 C/T cg16049864 chr8:95962084 TP53INP1 0.57 6.33 0.32 7.64e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs61931739 0.534 rs1211286 chr12:34135581 T/C cg26384229 chr12:38710491 ALG10B 0.45 6.26 0.32 1.16e-9 Morning vs. evening chronotype; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg26338869 chr17:61819248 STRADA 0.53 7.18 0.36 4.33e-12 Height; LIHC cis rs10744422 1.000 rs10744434 chr12:123368419 T/A cg25930673 chr12:123319894 HIP1R -0.9 -11.78 -0.54 4.15e-27 Schizophrenia; LIHC cis rs7618501 0.635 rs34080578 chr3:50026029 A/C cg24110177 chr3:50126178 RBM5 -0.48 -7.73 -0.39 1.21e-13 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.615 rs7502342 chr17:56922629 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.6 0.56 3.51e-30 Cognitive test performance; LIHC cis rs72781680 0.566 rs6713865 chr2:23899807 A/G cg08917208 chr2:24149416 ATAD2B 0.63 6.18 0.32 1.85e-9 Lymphocyte counts; LIHC trans rs668210 0.947 rs610497 chr11:65765551 C/T cg17712092 chr4:129076599 LARP1B 0.59 7.42 0.37 9.19e-13 Cerebrospinal fluid biomarker levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03535439 chr6:42981950 MEA1;KLHDC3 -0.41 -6.34 -0.32 7.35e-10 Pancreatic cancer; LIHC cis rs898097 0.691 rs7222773 chr17:80907283 A/G cg15664640 chr17:80829946 TBCD 0.43 7.28 0.37 2.36e-12 Breast cancer; LIHC cis rs9814567 0.712 rs4245905 chr3:134328864 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg05564831 chr3:52568323 NT5DC2 0.35 5.79 0.3 1.59e-8 Bipolar disorder; LIHC cis rs12365397 1.000 rs10838074 chr11:43233816 A/G cg16667275 chr11:43333495 API5 0.44 6.11 0.31 2.67e-9 Migraine; LIHC cis rs727505 1.000 rs6952721 chr7:124480075 T/C cg23710748 chr7:124431027 NA -0.32 -5.74 -0.3 2.09e-8 Lewy body disease; LIHC cis rs2230307 0.536 rs496798 chr1:100507990 G/A cg24955406 chr1:100503596 HIAT1 0.62 6.14 0.32 2.27e-9 Carotid intima media thickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23964739 chr19:45909864 CD3EAP;PPP1R13L 0.51 6.86 0.35 3.26e-11 Lung function (FEV1/FVC); LIHC cis rs7208859 0.673 rs9899943 chr17:29223925 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs561341 0.629 rs7216107 chr17:30224419 G/A cg20587970 chr11:113659929 NA -0.52 -6.68 -0.34 9.89e-11 Hip circumference adjusted for BMI; LIHC cis rs9457247 1.000 rs413232 chr6:167400972 G/A cg12798992 chr6:167411361 FGFR1OP 0.6 9.95 0.47 1.18e-20 Crohn's disease; LIHC trans rs6489882 0.779 rs57484342 chr12:113371973 A/G cg10175203 chr3:128143634 NA 0.38 6.13 0.31 2.41e-9 Chronic lymphocytic leukemia; LIHC cis rs17253792 0.915 rs28537145 chr14:56179119 G/A cg01858014 chr14:56050164 KTN1 -0.76 -8.08 -0.4 1.1e-14 Putamen volume; LIHC cis rs344364 0.518 rs1657129 chr16:1945826 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.44 -0.37 8.31e-13 Glomerular filtration rate in chronic kidney disease; LIHC cis rs9300255 0.509 rs641760 chr12:123518866 T/C cg05973401 chr12:123451056 ABCB9 0.47 6.02 0.31 4.43e-9 Neutrophil percentage of white cells; LIHC cis rs7131987 0.683 rs12366505 chr12:29474110 C/T cg05697976 chr12:29376483 FAR2 0.31 6.2 0.32 1.62e-9 QT interval; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg23522508 chr19:11287505 KANK2 0.4 6.18 0.32 1.8e-9 Bilirubin levels; LIHC cis rs12477438 0.520 rs6717723 chr2:99756930 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs67311347 0.869 rs7646899 chr3:40366982 A/G cg09455208 chr3:40491958 NA 0.33 6.43 0.33 4.32e-10 Renal cell carcinoma; LIHC cis rs1801251 0.963 rs13021246 chr2:233623111 T/C cg08000102 chr2:233561755 GIGYF2 0.76 11.5 0.53 4.14e-26 Coronary artery disease; LIHC cis rs1008375 0.966 rs4698638 chr4:17632988 G/C cg02297831 chr4:17616191 MED28 0.5 7.9 0.39 3.86e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1816752 0.719 rs11841989 chr13:24997698 C/A cg02811702 chr13:24901961 NA 0.26 6.34 0.32 7.35e-10 Obesity-related traits; LIHC cis rs11229555 0.645 rs6591475 chr11:58193551 G/T cg15696309 chr11:58395628 NA 0.66 7.85 0.39 5.24e-14 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2354432 0.556 rs12568866 chr1:146718430 A/C cg25205988 chr1:146714368 CHD1L -0.88 -10.54 -0.5 1.09e-22 Mitochondrial DNA levels; LIHC cis rs4474465 0.831 rs10899510 chr11:78170841 G/A cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs5769765 0.955 rs6520066 chr22:50294988 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.69 -9.04 -0.44 1.17e-17 Schizophrenia; LIHC cis rs12477438 0.798 rs2045057 chr2:99684929 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.53 -0.49 1.24e-22 Chronic sinus infection; LIHC cis rs2408955 0.561 rs11168365 chr12:48421772 A/G cg21466736 chr12:48725269 NA 0.54 7.26 0.37 2.57e-12 Glycated hemoglobin levels; LIHC cis rs3020736 0.500 rs8138678 chr22:42516229 A/G cg04733989 chr22:42467013 NAGA -0.65 -9.36 -0.45 1.11e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs1577917 0.958 rs7739241 chr6:86575796 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -7.95 -0.4 2.66e-14 Response to antipsychotic treatment; LIHC cis rs1419980 0.730 rs7965446 chr12:7747134 C/T cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs2412488 0.888 rs7698792 chr4:54319911 C/T cg22241045 chr4:54363911 LNX1 -0.42 -6.78 -0.34 5.27e-11 DNA methylation (variation); LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg07677032 chr17:61819896 STRADA -0.41 -5.81 -0.3 1.46e-8 Prudent dietary pattern; LIHC cis rs6466055 0.669 rs1142 chr7:104756326 C/T cg04380332 chr7:105027541 SRPK2 -0.3 -6.0 -0.31 5.12e-9 Schizophrenia; LIHC cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Electroencephalogram traits; LIHC cis rs2204008 0.665 rs11495668 chr12:38221018 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.74 0.3 2.11e-8 Bladder cancer; LIHC cis rs1577917 0.883 rs2166664 chr6:86596622 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.39 -7.2 -0.36 3.95e-12 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs7937682 0.924 rs499750 chr11:111513645 T/G cg09085632 chr11:111637200 PPP2R1B -1.06 -12.78 -0.57 7.85e-31 Primary sclerosing cholangitis; LIHC cis rs6089584 0.606 rs2296082 chr20:60573983 A/G cg06108461 chr20:60628389 TAF4 -0.54 -7.38 -0.37 1.2e-12 Body mass index; LIHC cis rs950169 0.922 rs11631096 chr15:85100929 G/C cg12863693 chr15:85201151 NMB 0.41 5.74 0.3 2.09e-8 Schizophrenia; LIHC cis rs4474465 0.688 rs4945302 chr11:78283454 T/C cg27205649 chr11:78285834 NARS2 0.5 7.84 0.39 5.74e-14 Alzheimer's disease (survival time); LIHC cis rs73191547 0.706 rs1905634 chr8:10051748 C/G cg21625330 chr8:9911636 MSRA 0.39 6.02 0.31 4.48e-9 Schizophrenia; LIHC cis rs7572733 0.534 rs770657 chr2:198674184 C/A cg10820045 chr2:198174542 NA 0.47 7.03 0.36 1.12e-11 Dermatomyositis; LIHC cis rs3768617 0.528 rs3736888 chr1:183084607 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.54 0.5 1.12e-22 Fuchs's corneal dystrophy; LIHC cis rs16958440 0.867 rs79712753 chr18:44676727 C/A cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs9914988 0.943 rs59461345 chr17:27151852 G/T cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC trans rs561341 1.000 rs15654 chr17:30326360 A/C cg20587970 chr11:113659929 NA -1.39 -11.8 -0.54 3.55e-27 Hip circumference adjusted for BMI; LIHC trans rs2270927 0.510 rs34596551 chr5:75577143 C/T cg13563193 chr19:33072644 PDCD5 0.97 9.09 0.44 8.16e-18 Mean corpuscular volume; LIHC cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.16 18.04 0.7 1.36e-51 Gut microbiome composition (summer); LIHC cis rs4759375 1.000 rs12366872 chr12:123804721 G/C cg00376283 chr12:123451042 ABCB9 -0.5 -6.4 -0.33 5.02e-10 HDL cholesterol; LIHC cis rs6835098 0.923 rs9997477 chr4:174112543 C/T cg27433088 chr4:174089019 GALNT7 0.4 6.89 0.35 2.73e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs1062177 1.000 rs2964585 chr5:151141895 C/T cg00977110 chr5:151150581 G3BP1 0.56 7.04 0.36 1.08e-11 Preschool internalizing problems; LIHC cis rs66887589 0.967 rs1155577 chr4:120449810 C/T cg09307838 chr4:120376055 NA -0.45 -6.76 -0.34 5.97e-11 Diastolic blood pressure; LIHC cis rs2842992 0.915 rs2758335 chr6:160111011 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.76 0.43 9.46e-17 Age-related macular degeneration (geographic atrophy); LIHC trans rs28735056 0.572 rs4799100 chr18:77640207 A/G cg05926928 chr17:57297772 GDPD1 -0.52 -7.72 -0.39 1.26e-13 Schizophrenia; LIHC cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg16405210 chr4:1374714 KIAA1530 0.7 10.47 0.49 1.99e-22 Obesity-related traits; LIHC cis rs1707322 0.752 rs3811435 chr1:46125790 C/A cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9910055 0.540 rs609292 chr17:42180436 G/A cg19774624 chr17:42201019 HDAC5 0.52 6.52 0.33 2.59e-10 Total body bone mineral density; LIHC cis rs15676 0.947 rs2997922 chr9:131580744 C/T cg00228799 chr9:131580591 ENDOG 0.47 7.15 0.36 5.24e-12 Blood metabolite levels; LIHC cis rs16828019 0.777 rs2300658 chr1:41505022 G/A cg03962019 chr1:41807865 NA 0.49 7.03 0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs1003719 0.788 rs2835600 chr21:38468958 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs644799 0.672 rs61902245 chr11:95517737 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.8 12.3 0.55 4.74e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9918079 0.560 rs6414767 chr4:15655721 A/G cg21123203 chr4:15471301 CC2D2A -0.46 -7.35 -0.37 1.48e-12 Obesity-related traits; LIHC trans rs11098499 0.863 rs58452170 chr4:120459674 A/T cg25214090 chr10:38739885 LOC399744 0.61 9.87 0.47 2.18e-20 Corneal astigmatism; LIHC trans rs2243480 1.000 rs1638734 chr7:66097539 A/C cg07424592 chr7:64974309 NA 0.76 8.62 0.42 2.49e-16 Diabetic kidney disease; LIHC trans rs11671005 0.610 rs4756 chr19:59074653 T/C cg22037779 chr5:139682734 PFDN1 -0.54 -6.72 -0.34 7.54e-11 Mean platelet volume; LIHC cis rs7592578 0.581 rs59109438 chr2:191287683 A/G cg10560079 chr2:191398806 TMEM194B -0.78 -11.26 -0.52 3.07e-25 Diastolic blood pressure; LIHC cis rs3736485 0.934 rs17609812 chr15:51879260 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10174077 0.874 rs10186656 chr2:152475938 T/G cg06191203 chr2:152266755 RIF1 -0.42 -7.17 -0.36 4.62e-12 Squamous cell lung carcinoma; LIHC cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg11070056 chr1:107600091 PRMT6 -0.63 -10.6 -0.5 6.9e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.42 0.56 1.8e-29 Prudent dietary pattern; LIHC cis rs8027181 0.839 rs8033073 chr15:73051093 G/A cg25996835 chr15:72978165 BBS4;HIGD2B 0.48 7.38 0.37 1.24e-12 Triglyceride levels; LIHC cis rs1005277 0.579 rs1780121 chr10:38529437 C/A cg18963800 chr10:38644991 HSD17B7P2 -0.43 -6.34 -0.32 7.08e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6964587 1.000 rs415 chr7:91580490 A/G cg17063962 chr7:91808500 NA -1.02 -19.48 -0.73 2.17e-57 Breast cancer; LIHC cis rs11690935 0.632 rs12998411 chr2:172530707 G/C cg13550731 chr2:172543902 DYNC1I2 0.63 11.35 0.52 1.55e-25 Schizophrenia; LIHC cis rs1008375 1.000 rs6849704 chr4:17652031 G/C cg16339924 chr4:17578868 LAP3 0.44 6.28 0.32 1.04e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs651907 0.557 rs34181125 chr3:101490278 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.45 -6.35 -0.32 6.96e-10 Colorectal cancer; LIHC cis rs17106184 0.892 rs116692933 chr1:51136273 T/C cg07174182 chr1:51127561 FAF1 -0.76 -8.12 -0.4 8.47e-15 Type 2 diabetes; LIHC cis rs929354 0.772 rs933344 chr7:157011265 A/T cg17757837 chr7:157058334 UBE3C 0.74 12.01 0.54 5.62e-28 Body mass index; LIHC cis rs2479724 0.792 rs7739064 chr6:41834037 C/A cg17623882 chr6:41773611 USP49 -0.57 -9.22 -0.45 3.16e-18 Menarche (age at onset); LIHC cis rs1865760 0.929 rs1436307 chr6:25939723 C/T cg15691649 chr6:25882328 NA -0.39 -6.15 -0.32 2.17e-9 Height; LIHC cis rs3096299 0.838 rs3102384 chr16:89411661 T/G cg08822215 chr16:89438651 ANKRD11 -0.44 -6.87 -0.35 3.14e-11 Multiple myeloma (IgH translocation); LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs71007656 1 rs71007656 chr10:37970845 CGGCTG/C cg25427524 chr10:38739819 LOC399744 -0.61 -11.41 -0.53 9.22e-26 Extrinsic epigenetic age acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24675879 chr17:28444056 MIR423;CCDC55 0.41 6.24 0.32 1.31e-9 Cognitive function; LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg25811766 chr13:21894605 NA 0.81 14.58 0.62 8.65e-38 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs10736390 1.000 rs10736390 chr1:55103945 A/G cg01517571 chr1:55089959 ACOT11;FAM151A -0.46 -7.97 -0.4 2.46e-14 Survival in pancreatic cancer; LIHC cis rs7412746 0.634 rs7521592 chr1:150821691 A/C cg18016565 chr1:150552671 MCL1 0.55 10.21 0.48 1.5e-21 Melanoma; LIHC cis rs9534288 0.797 rs9526134 chr13:46618046 G/T cg15192986 chr13:46630673 CPB2 -0.53 -8.1 -0.4 9.58e-15 Blood protein levels; LIHC cis rs10504073 0.647 rs28685207 chr8:50003484 A/G cg00325661 chr8:49890786 NA 0.31 7.12 0.36 6.58e-12 Blood metabolite ratios; LIHC cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg12310025 chr6:25882481 NA 0.57 7.71 0.38 1.35e-13 Blood metabolite levels; LIHC cis rs2777491 0.574 rs28700583 chr15:41714072 C/T cg18705301 chr15:41695430 NDUFAF1 -1.24 -18.49 -0.71 2.06e-53 Ulcerative colitis; LIHC cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg11062466 chr8:58055876 NA 0.4 5.91 0.3 8.29e-9 Developmental language disorder (linguistic errors); LIHC cis rs6542838 0.641 rs13005124 chr2:99527680 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.45 -6.53 -0.33 2.42e-10 Fear of minor pain; LIHC cis rs4141404 0.851 rs8135417 chr22:31559255 G/A cg13145458 chr22:31556086 RNF185 0.46 6.44 0.33 4.09e-10 Paclitaxel-induced neuropathy; LIHC cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg03806693 chr22:41940476 POLR3H -1.14 -13.48 -0.59 1.66e-33 Vitiligo; LIHC cis rs1816752 0.749 rs77832754 chr13:24990154 G/A cg22771759 chr13:24902376 NA 0.3 6.02 0.31 4.43e-9 Obesity-related traits; LIHC cis rs1670533 1.000 rs641987 chr4:1077542 C/T cg27284194 chr4:1044797 NA 0.59 8.76 0.43 9.11e-17 Recombination rate (females); LIHC cis rs12744310 0.887 rs35807669 chr1:41801652 C/T cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs6489882 0.867 rs4988618 chr12:113363178 G/A cg10175203 chr3:128143634 NA 0.39 6.38 0.33 5.72e-10 Chronic lymphocytic leukemia; LIHC cis rs7904368 0.754 rs11254231 chr10:16870246 A/G cg23933602 chr10:16859644 RSU1 0.59 5.76 0.3 1.83e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs1005277 0.579 rs1740747 chr10:38520465 G/A cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC trans rs7618501 0.572 rs4688756 chr3:50040194 T/A cg21665057 chr3:196295764 WDR53;FBXO45 0.56 9.31 0.45 1.57e-18 Intelligence (multi-trait analysis); LIHC cis rs7223966 1.000 rs7209758 chr17:61913621 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.75 0.34 6.37e-11 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs7246657 0.765 rs7247259 chr19:37851090 T/C cg10208301 chr11:6592745 DNHD1 0.48 6.96 0.35 1.71e-11 Coronary artery calcification; LIHC cis rs35306767 0.859 rs11817793 chr10:878895 C/T cg20503657 chr10:835505 NA 1.05 12.55 0.56 5.55e-30 Eosinophil percentage of granulocytes; LIHC cis rs2439831 0.867 rs2920781 chr15:43924682 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.98 0.35 1.56e-11 Lung cancer in ever smokers; LIHC cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg18230493 chr5:56204884 C5orf35 -0.45 -6.16 -0.32 2.04e-9 Initial pursuit acceleration; LIHC cis rs4474465 1.000 rs11237514 chr11:78180179 A/G cg02023728 chr11:77925099 USP35 0.36 6.32 0.32 8.31e-10 Alzheimer's disease (survival time); LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs6723226 0.638 rs6543657 chr2:32705085 T/C cg02381751 chr2:32503542 YIPF4 0.65 9.77 0.47 4.93e-20 Intelligence (multi-trait analysis); LIHC cis rs9583531 0.600 rs3809344 chr13:111358705 G/A cg15841412 chr13:111365552 ING1 0.47 5.87 0.3 1.06e-8 Coronary artery disease; LIHC cis rs12530845 0.623 rs73721669 chr7:135347107 C/G cg23117316 chr7:135346802 PL-5283 -0.4 -5.83 -0.3 1.27e-8 Red blood cell traits; LIHC cis rs9381040 1.000 rs2093396 chr6:41155000 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.38 -0.33 5.64e-10 Alzheimer's disease (late onset); LIHC cis rs7727544 0.684 rs272893 chr5:131663062 T/C cg07395648 chr5:131743802 NA -0.3 -6.11 -0.31 2.7e-9 Blood metabolite levels; LIHC cis rs7584330 0.744 rs10929234 chr2:238380034 C/G cg14458575 chr2:238380390 NA -0.54 -7.94 -0.39 2.99e-14 Prostate cancer; LIHC cis rs7208859 0.623 rs609063 chr17:28951513 A/G cg14067834 chr17:29058358 SUZ12P 0.64 6.28 0.32 1.01e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13256369 0.901 rs12681298 chr8:8566235 A/G cg18904891 chr8:8559673 CLDN23 -0.71 -12.82 -0.57 5.63e-31 Obesity-related traits; LIHC cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg10802521 chr3:52805072 NEK4 -0.43 -6.94 -0.35 2.01e-11 Bipolar disorder; LIHC cis rs8062405 0.755 rs62034350 chr16:28562256 A/G cg07451762 chr16:28383216 NA 0.39 7.05 0.36 9.95e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg05564831 chr3:52568323 NT5DC2 0.37 5.92 0.3 8.04e-9 Bipolar disorder; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04305677 chr7:2281541 NUDT1;FTSJ2 0.41 6.39 0.33 5.3e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4407350 0.837 rs5765707 chr22:44909507 A/T cg11695653 chr22:44894386 LDOC1L -0.37 -6.16 -0.32 2.01e-9 Intelligence (multi-trait analysis); LIHC cis rs10504073 0.584 rs4873307 chr8:49950417 C/T cg00325661 chr8:49890786 NA 0.33 7.6 0.38 2.84e-13 Blood metabolite ratios; LIHC cis rs7246657 0.943 rs10422074 chr19:37894236 T/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs6840360 1.000 rs1877187 chr4:152605621 C/T cg22705602 chr4:152727874 NA -0.29 -5.95 -0.31 6.53e-9 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.702 rs11076834 chr16:4549583 C/G cg04083430 chr16:4736063 MGRN1 -0.42 -6.05 -0.31 3.84e-9 Schizophrenia; LIHC cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg20818283 chr2:191399100 TMEM194B 0.46 6.19 0.32 1.75e-9 Pulse pressure; LIHC cis rs1371867 0.641 rs1788209 chr8:101337056 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -8.66 -0.42 1.88e-16 Atrioventricular conduction; LIHC cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg11890956 chr21:40555474 PSMG1 1.07 16.04 0.66 1.47e-43 Cognitive function; LIHC cis rs7103648 0.643 rs12365079 chr11:47696596 A/T cg20307385 chr11:47447363 PSMC3 0.99 16.22 0.66 2.8e-44 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg05368731 chr17:41323189 NBR1 0.71 12.04 0.55 4.57e-28 Menopause (age at onset); LIHC cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg11941060 chr3:133502564 NA -0.41 -6.13 -0.31 2.38e-9 Iron status biomarkers; LIHC cis rs2806561 0.704 rs636940 chr1:23522967 A/T cg12483005 chr1:23474871 LUZP1 0.47 7.24 0.36 3.01e-12 Height; LIHC cis rs4713118 0.869 rs2056925 chr6:27690905 A/G cg20933634 chr6:27740509 NA 0.46 6.06 0.31 3.53e-9 Parkinson's disease; LIHC cis rs2845885 1.000 rs11231698 chr11:63877163 C/T cg19006947 chr11:64034861 PLCB3 -0.45 -6.26 -0.32 1.17e-9 Body mass index; LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg00280220 chr17:61926910 NA 0.41 6.67 0.34 1.02e-10 Prudent dietary pattern; LIHC cis rs7715806 0.500 rs17563974 chr5:75004175 G/A cg00601450 chr5:74908170 NA 0.58 7.1 0.36 7.09e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs35883536 0.967 rs1577509 chr1:101089253 C/T cg14515779 chr1:101123966 NA -0.68 -13.21 -0.58 1.81e-32 Monocyte count; LIHC cis rs11677370 0.603 rs10178523 chr2:3854169 G/A cg17052675 chr2:3827356 NA -0.51 -6.52 -0.33 2.49e-10 Type 2 diabetes; LIHC cis rs7534824 0.625 rs12565777 chr1:101485794 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.7 7.03 0.36 1.13e-11 Refractive astigmatism; LIHC cis rs459571 1.000 rs456207 chr9:136911140 G/A cg13789015 chr9:136890014 NCRNA00094 0.43 7.88 0.39 4.32e-14 Platelet distribution width; LIHC cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg18252515 chr7:66147081 NA 1.28 16.95 0.68 3.23e-47 Diabetic kidney disease; LIHC cis rs6430585 0.528 rs309151 chr2:136661150 C/T cg25344623 chr2:136566232 LCT -0.37 -6.06 -0.31 3.66e-9 Corneal structure; LIHC cis rs4927850 1.000 rs7625570 chr3:195747398 A/G cg12923728 chr3:195709715 SDHAP1 -0.73 -10.48 -0.49 1.82e-22 Pancreatic cancer; LIHC cis rs1707322 0.752 rs28550303 chr1:46188914 G/T cg03146154 chr1:46216737 IPP 0.58 9.63 0.46 1.42e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs778691 chr7:65873092 G/C cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC trans rs4566357 0.615 rs10198406 chr2:227913539 A/G cg16088116 chr21:44841560 SIK1 -0.4 -6.23 -0.32 1.4e-9 Coronary artery disease; LIHC cis rs992157 0.835 rs2292551 chr2:219143229 G/A cg00012203 chr2:219082015 ARPC2 -0.82 -13.08 -0.58 5.58e-32 Colorectal cancer; LIHC cis rs853679 0.517 rs9380056 chr6:28104476 C/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs2304456 1.000 rs2304456 chr3:186445052 G/T cg12454167 chr3:186435060 KNG1 -0.35 -6.31 -0.32 8.54e-10 Blood protein levels; LIHC cis rs7572733 0.534 rs4550664 chr2:198691405 C/T cg00792783 chr2:198669748 PLCL1 0.46 6.78 0.34 5.42e-11 Dermatomyositis; LIHC trans rs1814175 0.740 rs10839439 chr11:49918240 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg18357526 chr6:26021779 HIST1H4A 0.62 8.73 0.43 1.18e-16 Blood metabolite levels; LIHC cis rs9916302 0.851 rs9904919 chr17:37556431 G/C cg00129232 chr17:37814104 STARD3 0.41 6.64 0.34 1.2e-10 Glomerular filtration rate (creatinine); LIHC cis rs875971 1.000 rs12533997 chr7:65965377 A/G cg18876405 chr7:65276391 NA 0.37 6.66 0.34 1.08e-10 Aortic root size; LIHC cis rs11971779 0.680 rs6962366 chr7:139043867 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs611744 0.935 rs661036 chr8:109213088 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs17376456 0.825 rs10214278 chr5:93237679 C/T cg25358565 chr5:93447407 FAM172A -1.01 -9.18 -0.44 4.2e-18 Diabetic retinopathy; LIHC trans rs1814175 0.817 rs1996982 chr11:49972619 G/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13482356 chr1:118148519 FAM46C 0.47 6.92 0.35 2.23e-11 Pancreatic cancer; LIHC trans rs2727020 0.702 rs609054 chr11:49219725 C/G cg15704280 chr7:45808275 SEPT13 0.88 16.29 0.66 1.46e-44 Coronary artery disease; LIHC trans rs11098499 0.754 rs66900435 chr4:120249425 C/A cg25214090 chr10:38739885 LOC399744 0.5 8.16 0.4 6.69e-15 Corneal astigmatism; LIHC cis rs12744310 1.000 rs12030762 chr1:41766761 T/C cg03962019 chr1:41807865 NA 0.38 6.22 0.32 1.46e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1215050 0.740 rs783929 chr4:98972495 T/A cg05340658 chr4:99064831 C4orf37 -0.4 -6.16 -0.32 2.04e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17776563 0.887 rs58548047 chr15:89123073 T/C cg05013243 chr15:89149849 MIR1179 0.37 6.06 0.31 3.5e-9 Thyroid hormone levels; LIHC cis rs11098499 0.754 rs878376 chr4:120237702 G/A cg09307838 chr4:120376055 NA 0.7 10.95 0.51 4.17e-24 Corneal astigmatism; LIHC cis rs1395 0.922 rs4665376 chr2:27509032 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.01 -0.31 4.81e-9 Blood metabolite levels; LIHC cis rs1278769 0.735 rs12585036 chr13:113535741 C/T cg00823993 chr13:113535758 ATP11A 0.6 7.27 0.37 2.48e-12 Interstitial lung disease; LIHC cis rs1862618 0.671 rs2034244 chr5:56242774 T/C cg12311346 chr5:56204834 C5orf35 0.44 5.91 0.3 8.44e-9 Initial pursuit acceleration; LIHC cis rs4820294 1.000 rs7291867 chr22:38062112 C/G cg10587741 chr22:38071170 LGALS1 0.72 12.43 0.56 1.64e-29 Fat distribution (HIV); LIHC cis rs6429082 0.875 rs2291688 chr1:235594250 A/G cg26050004 chr1:235667680 B3GALNT2 -0.4 -6.28 -0.32 1e-9 Adiposity; LIHC cis rs6570726 0.791 rs9376953 chr6:145912226 G/T cg23711669 chr6:146136114 FBXO30 0.73 12.2 0.55 1.17e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs1003719 0.788 rs1543750 chr21:38446918 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs6674176 0.597 rs3762422 chr1:44400532 T/A cg12908607 chr1:44402522 ARTN -0.49 -8.44 -0.42 8.83e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs2243480 1.000 rs781150 chr7:65480973 C/T cg10756647 chr7:56101905 PSPH 1.08 13.33 0.58 5.93e-33 Diabetic kidney disease; LIHC cis rs1707322 1.000 rs11211190 chr1:46266255 C/T cg03146154 chr1:46216737 IPP 0.47 7.52 0.38 4.71e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10876993 0.890 rs1689597 chr12:58051886 G/A cg15848620 chr12:58087721 OS9 -0.55 -7.44 -0.37 8.41e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs5769707 0.656 rs135878 chr22:50014369 T/A cg01652190 chr22:50026171 C22orf34 -0.34 -7.43 -0.37 8.63e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs3736485 0.934 rs2414105 chr15:51868373 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.06 -0.31 3.5e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6728642 0.572 rs7574488 chr2:97599618 T/C cg26665480 chr2:98280029 ACTR1B -0.51 -6.4 -0.33 5.1e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg06656553 chr16:89960601 TCF25 -0.49 -6.26 -0.32 1.13e-9 Skin colour saturation; LIHC cis rs3823572 0.542 rs10224226 chr7:133626662 G/A cg03336402 chr7:133662267 EXOC4 0.49 5.98 0.31 5.58e-9 Intelligence (multi-trait analysis); LIHC cis rs12701220 0.655 rs34696066 chr7:1140919 C/T cg00990874 chr7:1149470 C7orf50 -0.69 -9.84 -0.47 2.87e-20 Bronchopulmonary dysplasia; LIHC cis rs1552244 0.554 rs6762397 chr3:10007840 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.52 6.71 0.34 8.1e-11 Alzheimer's disease; LIHC cis rs904251 0.802 rs2646933 chr6:37402070 C/G cg01843034 chr6:37503916 NA -0.37 -6.06 -0.31 3.66e-9 Cognitive performance; LIHC cis rs5769765 0.862 rs138856 chr22:50199378 G/T cg02269571 chr22:50332266 NA -0.64 -8.36 -0.41 1.59e-15 Schizophrenia; LIHC cis rs910316 0.763 rs175016 chr14:75459633 C/T cg11812906 chr14:75593930 NEK9 -0.74 -14.02 -0.6 1.38e-35 Height; LIHC cis rs796364 0.806 rs11684895 chr2:201009026 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs12980942 1.000 rs12984160 chr19:41815713 A/G cg25627403 chr19:41769009 HNRNPUL1 0.56 6.84 0.35 3.72e-11 Coronary artery disease; LIHC cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg22764044 chr5:178986830 RUFY1 -0.4 -6.0 -0.31 4.89e-9 Lung cancer; LIHC cis rs67478160 0.619 rs11628481 chr14:104241499 C/T cg08213375 chr14:104286397 PPP1R13B 0.66 12.93 0.57 2.14e-31 Schizophrenia; LIHC cis rs7208859 0.673 rs75142521 chr17:29240537 G/A cg13385521 chr17:29058706 SUZ12P 0.78 7.51 0.38 5.3e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4742903 0.904 rs966390 chr9:106944031 A/G cg14250997 chr9:106856677 SMC2 0.35 5.94 0.31 7.01e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs13217239 0.646 rs10946888 chr6:26951678 A/G cg18867708 chr6:26865862 GUSBL1 0.51 7.97 0.4 2.44e-14 Schizophrenia; LIHC cis rs2304069 0.954 rs1433010 chr5:149383954 C/G cg12661370 chr5:149340060 SLC26A2 -0.5 -6.13 -0.31 2.42e-9 HIV-1 control; LIHC cis rs1997103 0.863 rs6956287 chr7:55415107 T/C cg17469321 chr7:55412551 NA 0.52 7.43 0.37 8.78e-13 QRS interval (sulfonylurea treatment interaction); LIHC cis rs12142240 0.698 rs9661240 chr1:46827050 G/A cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs4820294 1.000 rs4820294 chr22:38071043 G/A cg00292662 chr22:38071168 LGALS1 0.65 10.28 0.49 9.01e-22 Fat distribution (HIV); LIHC trans rs2727020 0.894 rs3862342 chr11:49357043 C/T cg03929089 chr4:120376271 NA -0.65 -9.66 -0.46 1.13e-19 Coronary artery disease; LIHC cis rs7618501 0.519 rs3774749 chr3:50207227 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.46 -6.71 -0.34 8.2e-11 Intelligence (multi-trait analysis); LIHC cis rs6429082 0.715 rs2172718 chr1:235580727 A/G cg26050004 chr1:235667680 B3GALNT2 -0.49 -7.42 -0.37 9.23e-13 Adiposity; LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg06873352 chr17:61820015 STRADA 0.54 8.19 0.4 5.44e-15 Height; LIHC cis rs11627756 0.846 rs1190336 chr14:103108478 A/G cg12046867 chr14:103022105 NA 0.37 5.8 0.3 1.48e-8 Mean platelet volume; LIHC cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC cis rs763121 0.853 rs10135 chr22:39082174 C/T cg14440974 chr22:39074834 NA 0.36 6.24 0.32 1.27e-9 Menopause (age at onset); LIHC cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg03806693 chr22:41940476 POLR3H 1.12 13.03 0.58 8.92e-32 Vitiligo; LIHC cis rs1577917 0.917 rs13213603 chr6:86534758 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs6424115 0.965 rs2502979 chr1:24149315 C/A cg15997130 chr1:24165203 NA 0.47 9.61 0.46 1.61e-19 Immature fraction of reticulocytes; LIHC cis rs6762477 0.748 rs3755831 chr3:50228767 G/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.55 -8.58 -0.42 3.47e-16 Menarche (age at onset); LIHC cis rs7662987 0.517 rs1154405 chr4:100008750 G/A cg12011299 chr4:100065546 ADH4 0.65 10.71 0.5 2.86e-23 Smoking initiation; LIHC cis rs9814567 0.929 rs1534027 chr3:134284662 T/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.3300000000000004e-09 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs11088226 0.681 rs11700671 chr21:33938621 T/A cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.1e-34 Gastritis; LIHC cis rs7927771 1.000 rs11039412 chr11:47841581 G/A cg20135002 chr11:47629003 NA -0.54 -9.17 -0.44 4.7e-18 Subjective well-being; LIHC cis rs7312933 0.703 rs12370778 chr12:42599696 T/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 7.61 0.38 2.63e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg26354017 chr1:205819088 PM20D1 0.77 11.25 0.52 3.28e-25 Menarche (age at onset); LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.46 7.19 0.36 4.13e-12 Prudent dietary pattern; LIHC cis rs826838 1.000 rs826888 chr12:39104719 C/G cg13010199 chr12:38710504 ALG10B -0.4 -5.87 -0.3 1.04e-8 Heart rate; LIHC cis rs6754311 0.628 rs309811 chr2:136625602 A/G cg15123519 chr2:136567270 LCT 0.43 8.95 0.44 2.29e-17 Mosquito bite size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19787033 chr11:77850962 ALG8 0.41 6.27 0.32 1.1e-9 Cognitive function; LIHC cis rs67311347 0.956 rs11714871 chr3:40428938 T/G cg09455208 chr3:40491958 NA 0.35 6.84 0.35 3.65e-11 Renal cell carcinoma; LIHC trans rs916888 0.773 rs199457 chr17:44795469 C/T cg26692224 chr17:62915920 LRRC37A3 -0.73 -6.94 -0.35 1.93e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs3812831 0.630 rs9562129 chr13:114917152 A/G cg08824895 chr13:115047677 UPF3A 0.45 6.55 0.33 2.08e-10 Schizophrenia; LIHC cis rs35306767 0.903 rs13377166 chr10:886259 G/A cg20503657 chr10:835505 NA 1.11 12.64 0.56 2.57e-30 Eosinophil percentage of granulocytes; LIHC cis rs1843834 0.611 rs1058360 chr2:225449242 A/T cg22455342 chr2:225449267 CUL3 0.6 8.75 0.43 1.02e-16 IgE levels in asthmatics (D.p. specific); LIHC trans rs4704846 0.660 rs72805202 chr5:156553390 A/C cg02632742 chr2:60187357 NA -0.6 -6.04 -0.31 3.99e-9 Blood protein levels; LIHC cis rs10744422 1.000 rs7972447 chr12:123354545 C/G cg25930673 chr12:123319894 HIP1R -0.86 -10.59 -0.5 7.73e-23 Schizophrenia; LIHC cis rs652260 0.967 rs569175 chr19:7901160 T/G cg26014689 chr19:7917955 EVI5L -0.67 -11.67 -0.53 1.03e-26 Menarche (age at onset); LIHC cis rs7017914 0.905 rs2639956 chr8:71924091 A/G cg27618939 chr8:71581788 XKR9;LACTB2 -0.37 -5.76 -0.3 1.83e-8 Bone mineral density; LIHC cis rs35883536 0.647 rs59667512 chr1:101046712 C/T cg14515779 chr1:101123966 NA 0.49 6.84 0.35 3.64e-11 Monocyte count; LIHC cis rs4466137 0.953 rs1585153 chr5:83000385 A/T cg16102102 chr5:83017553 HAPLN1 -0.57 -8.3 -0.41 2.5e-15 Prostate cancer; LIHC cis rs9868809 0.772 rs9821797 chr3:48718253 T/A cg07636037 chr3:49044803 WDR6 -0.56 -6.32 -0.32 8.37e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs875971 0.862 rs2420173 chr7:65645399 A/T cg11764359 chr7:65958608 NA -0.84 -14.15 -0.61 4.2500000000000003e-36 Aortic root size; LIHC cis rs2832191 0.933 rs2832236 chr21:30547602 C/T cg08807101 chr21:30365312 RNF160 -0.47 -7.16 -0.36 4.88e-12 Dental caries; LIHC cis rs7927771 1.000 rs12363232 chr11:47623890 C/T cg20135002 chr11:47629003 NA -0.58 -10.14 -0.48 2.58e-21 Subjective well-being; LIHC cis rs7552404 0.924 rs7544117 chr1:76158246 A/G cg22875332 chr1:76189707 ACADM 0.48 7.45 0.37 7.7e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7677751 0.767 rs890204 chr4:55064439 C/G cg17187183 chr4:55093834 PDGFRA 0.58 7.33 0.37 1.63e-12 Corneal astigmatism; LIHC cis rs1451375 0.617 rs12671474 chr7:50591395 C/A cg14593290 chr7:50529359 DDC 0.62 9.78 0.47 4.43e-20 Malaria; LIHC cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.59 0.38 2.99e-13 Electroencephalogram traits; LIHC cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs7707921 0.752 rs2406910 chr5:81308719 C/T cg15871215 chr5:81402204 ATG10 0.66 7.14 0.36 5.75e-12 Breast cancer; LIHC trans rs3749237 1.000 rs6804655 chr3:49738945 C/T cg21659725 chr3:3221576 CRBN 0.79 12.32 0.55 4.18e-29 Resting heart rate; LIHC cis rs2576037 0.796 rs2571031 chr18:44577063 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.21 -0.36 3.52e-12 Personality dimensions; LIHC cis rs2832191 1.000 rs2832183 chr21:30482150 G/A cg24692254 chr21:30365293 RNF160 -0.65 -11.59 -0.53 2.04e-26 Dental caries; LIHC cis rs3981351 0.797 rs12777332 chr10:115458936 A/G cg24846397 chr10:115438155 CASP7 -0.45 -6.99 -0.35 1.44e-11 Obesity-related traits; LIHC cis rs35150201 0.838 rs6959832 chr7:135289854 G/A cg23117316 chr7:135346802 PL-5283 -0.27 -5.73 -0.3 2.19e-8 Plateletcrit;Mean corpuscular hemoglobin;Mean platelet volume; LIHC cis rs9733 0.744 rs12125650 chr1:150760174 A/G cg17724175 chr1:150552817 MCL1 -0.37 -7.36 -0.37 1.35e-12 Tonsillectomy; LIHC cis rs67478160 0.584 rs2295147 chr14:104195664 A/G cg01849466 chr14:104193079 ZFYVE21 0.55 9.97 0.47 9.96e-21 Schizophrenia; LIHC cis rs7937890 0.904 rs67623158 chr11:14295196 T/C cg23387056 chr11:14280742 SPON1 0.45 6.17 0.32 1.9e-9 Mitochondrial DNA levels; LIHC cis rs921968 0.541 rs10200507 chr2:219335944 C/A cg02176678 chr2:219576539 TTLL4 -0.56 -7.81 -0.39 7.21e-14 Mean corpuscular hemoglobin concentration; LIHC trans rs7976838 0.831 rs17120243 chr12:60206636 A/G cg02574734 chr1:116369351 NA 0.49 6.21 0.32 1.55e-9 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC cis rs7589728 0.925 rs78829281 chr2:88502293 T/A cg07952391 chr2:88470173 THNSL2 0.77 7.15 0.36 5.27e-12 Plasma clusterin levels; LIHC cis rs6570726 0.791 rs6570692 chr6:145904401 T/A cg13319975 chr6:146136371 FBXO30 -0.39 -6.25 -0.32 1.22e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs801193 0.660 rs4610622 chr7:66224497 T/C cg11764359 chr7:65958608 NA 0.82 14.54 0.62 1.27e-37 Aortic root size; LIHC trans rs634534 0.622 rs501353 chr11:65739549 T/G cg17712092 chr4:129076599 LARP1B 0.7 11.59 0.53 1.98e-26 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs116248771 0.739 rs73156451 chr3:158365449 T/C cg16708174 chr3:158430962 RARRES1 0.47 6.28 0.32 1.04e-9 diarrhoeal disease at age 2; LIHC cis rs919433 0.963 rs12617117 chr2:198155170 T/A cg10820045 chr2:198174542 NA -0.59 -9.84 -0.47 2.85e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs507080 0.922 rs493834 chr11:118567444 A/G cg04173919 chr11:118528438 PHLDB1 0.36 6.68 0.34 9.53e-11 Serum metabolite levels; LIHC cis rs769267 0.930 rs9917108 chr19:19572785 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.16e-9 Tonsillectomy; LIHC cis rs7208859 0.623 rs9900144 chr17:29208389 T/C cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10771431 0.810 rs10771418 chr12:9358995 A/G cg08997352 chr12:9597637 DDX12 -0.56 -8.64 -0.42 2.25e-16 Breast size; LIHC cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg15691649 chr6:25882328 NA -0.59 -7.59 -0.38 3.12e-13 Intelligence (multi-trait analysis); LIHC cis rs6762477 0.748 rs34877766 chr3:50234126 A/G cg05260129 chr3:50388622 TUSC4;CYB561D2 0.51 7.12 0.36 6.39e-12 Menarche (age at onset); LIHC cis rs68170813 0.559 rs6946036 chr7:106853659 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg03721293 chr16:90014378 DEF8 -0.4 -6.79 -0.34 4.96e-11 Skin colour saturation; LIHC cis rs679087 1.000 rs302317 chr12:29921443 G/A cg14258853 chr12:29935411 TMTC1 -0.5 -7.88 -0.39 4.34e-14 Schizophrenia; LIHC cis rs17685 0.672 rs10952841 chr7:75778626 A/C cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7587476 0.548 rs35982594 chr2:215706075 G/A cg04004882 chr2:215674386 BARD1 0.5 5.93 0.31 7.6e-9 Neuroblastoma; LIHC cis rs12220238 0.730 rs11000899 chr10:75913055 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs877282 0.945 rs11253396 chr10:789754 C/T cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs9355610 0.892 rs2247314 chr6:167370230 T/C cg12798992 chr6:167411361 FGFR1OP -0.48 -7.52 -0.38 4.9e-13 Graves' disease; LIHC cis rs4742903 1.000 rs3818625 chr9:106856452 G/A cg14250997 chr9:106856677 SMC2 0.43 7.37 0.37 1.32e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs7238033 0.602 rs3819178 chr18:43310845 G/C cg20610511 chr18:43302872 SLC14A1 0.39 6.49 0.33 3.01e-10 Bladder cancer; LIHC cis rs1816752 0.870 rs9511261 chr13:25012018 C/T cg22771759 chr13:24902376 NA 0.32 6.8 0.35 4.62e-11 Obesity-related traits; LIHC cis rs4423214 0.921 rs12807827 chr11:71203790 A/C cg05163923 chr11:71159392 DHCR7 0.81 11.9 0.54 1.53e-27 Vitamin D levels; LIHC cis rs2153535 0.580 rs9406162 chr6:8466196 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC trans rs1814175 0.615 rs12417290 chr11:49876951 G/A cg03929089 chr4:120376271 NA -0.83 -15.93 -0.65 4.11e-43 Height; LIHC cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 8.73 0.43 1.13e-16 Platelet count; LIHC cis rs4642101 0.662 rs57411588 chr3:12820384 C/G cg24848339 chr3:12840334 CAND2 0.31 6.43 0.33 4.17e-10 QRS complex (12-leadsum); LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg13409248 chr3:40428643 ENTPD3 0.49 8.2 0.41 4.93e-15 Renal cell carcinoma; LIHC cis rs12586317 0.620 rs76293361 chr14:35570889 G/A cg05294307 chr14:35346193 BAZ1A -0.46 -6.71 -0.34 8.17e-11 Psoriasis; LIHC cis rs2070488 1.000 rs13074025 chr3:38455704 C/A cg24069376 chr3:38537580 EXOG 0.43 7.9 0.39 3.93e-14 Electrocardiographic conduction measures; LIHC cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg11890956 chr21:40555474 PSMG1 1.09 16.35 0.66 8.22e-45 Cognitive function; LIHC cis rs365132 0.818 rs251843 chr5:176476106 A/G cg16309518 chr5:176445507 NA -0.5 -9.32 -0.45 1.45e-18 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs826838 0.904 rs11612004 chr12:39204282 G/A cg26384229 chr12:38710491 ALG10B 0.84 10.92 0.51 5.28e-24 Heart rate; LIHC cis rs28830936 0.966 rs17678552 chr15:42066190 T/C cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.24 -0.32 1.29e-9 Diastolic blood pressure; LIHC cis rs7208859 0.623 rs383436 chr17:28959179 A/G cg14067834 chr17:29058358 SUZ12P 0.64 6.16 0.32 2.02e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs722599 0.651 rs7159354 chr14:75253847 A/G cg08847533 chr14:75593920 NEK9 0.5 7.51 0.38 5.22e-13 IgG glycosylation; LIHC cis rs903552 1.000 rs12903048 chr15:102006325 G/T cg19295451 chr15:102010161 PCSK6 -0.44 -6.12 -0.31 2.6e-9 Diabetic kidney disease; LIHC cis rs9790314 1.000 rs336590 chr3:161079583 G/A cg04691961 chr3:161091175 C3orf57 -0.44 -6.97 -0.35 1.62e-11 Morning vs. evening chronotype; LIHC cis rs17106184 0.892 rs12084054 chr1:51242141 C/T cg07174182 chr1:51127561 FAF1 -0.61 -6.69 -0.34 8.86e-11 Type 2 diabetes; LIHC cis rs6442522 0.640 rs6762964 chr3:15527445 G/C cg16303742 chr3:15540471 COLQ 0.39 6.19 0.32 1.72e-9 Uric acid levels; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg21782813 chr7:2030301 MAD1L1 0.56 10.27 0.49 9.91e-22 Bipolar disorder and schizophrenia; LIHC cis rs4820294 0.669 rs9622677 chr22:38054262 A/C cg10587741 chr22:38071170 LGALS1 0.44 7.93 0.39 3.22e-14 Fat distribution (HIV); LIHC cis rs11690935 0.959 rs3770451 chr2:172668715 T/G cg13550731 chr2:172543902 DYNC1I2 -0.92 -17.32 -0.68 1.03e-48 Schizophrenia; LIHC cis rs6430585 0.583 rs12373779 chr2:136586840 A/C cg15123519 chr2:136567270 LCT -0.38 -5.87 -0.3 1.02e-8 Corneal structure; LIHC trans rs6058796 1.000 rs6141333 chr20:31263324 C/A cg02600331 chr11:130417168 NA 0.36 7.86 0.39 4.98e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs10927875 0.632 rs6677321 chr1:16149301 A/C cg21385522 chr1:16154831 NA -1.06 -17.37 -0.68 7.03e-49 Dilated cardiomyopathy; LIHC cis rs2599510 0.744 rs4952212 chr2:32618493 G/C cg02381751 chr2:32503542 YIPF4 -0.51 -6.94 -0.35 1.97e-11 Interleukin-18 levels; LIHC cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg16325326 chr1:53192061 ZYG11B -0.41 -6.9 -0.35 2.57e-11 Monocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21558545 chr12:71834859 LGR5 0.42 6.2 0.32 1.63e-9 Pancreatic cancer; LIHC cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg02290350 chr8:58132656 NA 0.4 8.39 0.41 1.29e-15 Developmental language disorder (linguistic errors); LIHC trans rs7618501 0.633 rs9866695 chr3:50069452 G/T cg21659725 chr3:3221576 CRBN -0.7 -11.59 -0.53 2.03e-26 Intelligence (multi-trait analysis); LIHC cis rs17711722 0.583 rs11768292 chr7:65474801 G/T cg18876405 chr7:65276391 NA -0.52 -7.8 -0.39 7.46e-14 Calcium levels; LIHC cis rs2991971 0.729 rs10890328 chr1:45905383 G/T cg05343316 chr1:45956843 TESK2 0.48 7.16 0.36 4.82e-12 High light scatter reticulocyte count; LIHC cis rs12824058 0.831 rs11060826 chr12:130809931 G/C cg26677194 chr12:130822605 PIWIL1 0.52 7.36 0.37 1.36e-12 Menopause (age at onset); LIHC cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg20090690 chr10:134436459 INPP5A 0.45 6.07 0.31 3.45e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9296092 0.517 rs78978280 chr6:33520747 T/A cg13560919 chr6:33536144 NA -0.39 -6.31 -0.32 8.5e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs3015497 0.646 rs2934693 chr14:51101641 C/T cg09863266 chr14:51125203 SAV1 -0.42 -5.76 -0.3 1.91e-8 Mean platelet volume; LIHC cis rs9916302 0.904 rs1966916 chr17:37425238 T/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.49 -0.59 1.55e-33 Glomerular filtration rate (creatinine); LIHC cis rs765787 0.530 rs11854689 chr15:45516052 A/G cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs61990749 0.597 rs11623088 chr14:78137735 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.61 -10.17 -0.48 2.04e-21 Fibroblast growth factor basic levels; LIHC cis rs870825 0.929 rs72689263 chr4:185590961 C/T cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs6430585 0.583 rs3769012 chr2:136556480 C/T cg15123519 chr2:136567270 LCT -0.38 -5.98 -0.31 5.75e-9 Corneal structure; LIHC cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.82 8.07 0.4 1.22e-14 Platelet count; LIHC cis rs1190552 0.846 rs4906212 chr14:102981595 A/G cg10241871 chr14:102965420 TECPR2 0.47 7.26 0.37 2.57e-12 Blood protein levels; LIHC cis rs2075371 1.000 rs2075373 chr7:133984683 A/C cg11752832 chr7:134001865 SLC35B4 0.52 7.83 0.39 6.14e-14 Mean platelet volume; LIHC cis rs11792861 0.816 rs744980 chr9:111690388 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 9.1 0.44 7.64e-18 Menarche (age at onset); LIHC cis rs1712517 0.844 rs1163087 chr10:105043289 G/A cg05636881 chr10:105038444 INA 0.42 6.43 0.33 4.38e-10 Migraine; LIHC cis rs1190552 0.761 rs11626217 chr14:102866362 G/A cg10241871 chr14:102965420 TECPR2 0.39 5.92 0.3 7.95e-9 Blood protein levels; LIHC cis rs2404602 0.692 rs34272342 chr15:77012276 A/C cg03037974 chr15:76606532 NA 0.75 14.74 0.62 2.14e-38 Blood metabolite levels; LIHC cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.53 8.38 0.41 1.35e-15 Schizophrenia; LIHC cis rs9916302 0.904 rs8076546 chr17:37555403 G/A cg00129232 chr17:37814104 STARD3 0.42 6.74 0.34 6.58e-11 Glomerular filtration rate (creatinine); LIHC trans rs7823896 0.605 rs6989795 chr8:110086377 C/T cg11277220 chr19:9271193 ZNF317 0.64 6.17 0.32 1.94e-9 Myopia (pathological); LIHC cis rs26868 0.740 rs26869 chr16:2248786 T/C cg02248941 chr16:2239361 CASKIN1 0.34 6.51 0.33 2.64e-10 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14490972 chr6:43484812 POLR1C;YIPF3 -0.5 -6.17 -0.32 1.89e-9 Lung function (FEV1/FVC); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg15617548 chr2:171785815 GORASP2 -0.4 -6.41 -0.33 4.9e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg21548813 chr6:291882 DUSP22 -0.55 -7.33 -0.37 1.68e-12 Menopause (age at onset); LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg06876404 chr16:30941527 FBXL19 0.42 6.62 0.34 1.4e-10 Bipolar disorder; LIHC trans rs1814175 0.616 rs6486011 chr11:49740230 C/T cg03929089 chr4:120376271 NA -0.85 -16.54 -0.67 1.44e-45 Height; LIHC cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg08219700 chr8:58056026 NA 0.52 6.08 0.31 3.27e-9 Developmental language disorder (linguistic errors); LIHC cis rs9649213 0.593 rs6969234 chr7:97987986 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.26e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs6430585 0.583 rs7581814 chr2:136641593 C/G cg15123519 chr2:136567270 LCT 0.36 5.87 0.3 1.01e-8 Corneal structure; LIHC cis rs11229555 0.645 rs56228632 chr11:58187444 A/G cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs8180040 0.783 rs11710121 chr3:47351501 T/G cg16586182 chr3:47516702 SCAP 0.5 8.82 0.43 6.12e-17 Colorectal cancer; LIHC cis rs908922 0.676 rs12129646 chr1:152518816 C/T cg20991723 chr1:152506922 NA 0.54 9.22 0.45 3.2e-18 Hair morphology; LIHC cis rs743757 0.878 rs1467913 chr3:50525017 G/T cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.14 0.36 5.55e-12 Diastolic blood pressure; LIHC cis rs80282103 0.867 rs80254477 chr10:1077387 T/G cg20335179 chr10:1068567 C10orf110;IDI2 -0.61 -6.73 -0.34 7.32e-11 Glomerular filtration rate (creatinine); LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.11 0.55 2.44e-28 Height; LIHC cis rs7264396 0.635 rs6058375 chr20:34531997 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -10.44 -0.49 2.4e-22 Total cholesterol levels; LIHC cis rs9596863 1.000 rs9536557 chr13:54433190 A/G ch.13.53330881F chr13:54432880 NA -0.45 -6.43 -0.33 4.18e-10 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg11494091 chr17:61959527 GH2 0.43 7.97 0.4 2.46e-14 Prudent dietary pattern; LIHC trans rs208520 0.909 rs9453672 chr6:66991431 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.95 0.35 1.83e-11 Exhaled nitric oxide output; LIHC cis rs2257205 0.667 rs8076021 chr17:56694646 T/G cg05425664 chr17:57184151 TRIM37 -0.61 -6.69 -0.34 8.94e-11 Pancreatic cancer; LIHC cis rs1355223 0.583 rs2941043 chr11:34870994 A/G cg11058730 chr11:34937778 PDHX;APIP -0.73 -12.35 -0.56 3.21e-29 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs61990749 0.597 rs2032781 chr14:78214875 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.75 -0.39 1.02e-13 Fibroblast growth factor basic levels; LIHC cis rs7617773 0.746 rs7619865 chr3:48370580 G/A cg11946769 chr3:48343235 NME6 0.64 8.96 0.44 2.12e-17 Coronary artery disease; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg16822855 chr3:40428330 ENTPD3 0.33 5.93 0.31 7.32e-9 Renal cell carcinoma; LIHC cis rs11792861 0.816 rs28361186 chr9:111704064 G/A cg05043794 chr9:111880884 C9orf5 -0.29 -6.73 -0.34 7.19e-11 Menarche (age at onset); LIHC cis rs8016947 0.583 rs12891895 chr14:35827557 A/C cg03549618 chr14:35838977 NA 0.43 6.94 0.35 1.97e-11 Psoriasis; LIHC cis rs2997447 0.846 rs12069719 chr1:26411918 A/G cg19633962 chr1:26362018 EXTL1 -0.61 -7.16 -0.36 5.05e-12 QRS complex (12-leadsum); LIHC trans rs801193 1.000 rs62466793 chr7:66191517 G/A cg26939375 chr7:64535504 NA 0.42 6.82 0.35 4.26e-11 Aortic root size; LIHC trans rs1499614 1.000 rs60326618 chr7:66166358 G/A cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs6663390 0.510 rs73072979 chr1:208072057 G/A cg03990033 chr1:208084030 CD34 0.48 5.8 0.3 1.53e-8 Facial morphology (factor 18); LIHC cis rs763121 0.962 rs5757130 chr22:38937794 G/A cg06544989 chr22:39130855 UNC84B 0.35 5.71 0.3 2.45e-8 Menopause (age at onset); LIHC trans rs1814175 0.645 rs1851850 chr11:50012168 G/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg24693881 chr1:107596107 NA 0.55 9.61 0.46 1.64e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs35110281 0.811 rs7275705 chr21:45056453 G/C cg01579765 chr21:45077557 HSF2BP -0.34 -6.42 -0.33 4.6e-10 Mean corpuscular volume; LIHC cis rs8180040 1.000 rs295458 chr3:47385585 C/A cg27129171 chr3:47204927 SETD2 0.63 10.69 0.5 3.22e-23 Colorectal cancer; LIHC trans rs7618501 0.966 rs13085679 chr3:49869631 G/A cg21659725 chr3:3221576 CRBN 0.97 18.13 0.7 5.68e-52 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.894 rs2694632 chr2:61558682 T/C cg15711740 chr2:61764176 XPO1 0.42 5.79 0.3 1.56e-8 Tuberculosis; LIHC cis rs9916302 0.718 rs10445306 chr17:37591422 A/G cg03013999 chr17:37608204 MED1 0.35 5.8 0.3 1.49e-8 Glomerular filtration rate (creatinine); LIHC cis rs3814244 0.528 rs7306466 chr12:68408722 G/A cg15249341 chr12:68405565 NA -0.32 -6.27 -0.32 1.09e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs7712401 0.755 rs13172043 chr5:122184759 G/A cg18764291 chr5:122110994 SNX2 0.35 5.91 0.3 8.16e-9 Mean platelet volume; LIHC cis rs3762637 0.941 rs75344200 chr3:122073421 C/T cg24169773 chr3:122142474 KPNA1 -0.49 -9.64 -0.46 1.3e-19 LDL cholesterol levels; LIHC cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.1e-17 Bipolar disorder; LIHC cis rs10508774 1.000 rs72782254 chr10:32963332 C/A cg01819863 chr10:32635814 EPC1 0.63 5.79 0.3 1.62e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15397725 chr14:53019133 TXNDC16;GPR137C 0.43 6.33 0.32 7.73e-10 Pancreatic cancer; LIHC cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg11764359 chr7:65958608 NA 0.57 6.0 0.31 4.9e-9 Diabetic kidney disease; LIHC cis rs11167764 1.000 rs6887599 chr5:141484349 G/A cg23435118 chr5:141488016 NDFIP1 -0.44 -6.02 -0.31 4.6e-9 Crohn's disease; LIHC cis rs5769765 0.908 rs9616376 chr22:50310829 A/G cg26441486 chr22:50317300 CRELD2 0.36 5.73 0.3 2.16e-8 Schizophrenia; LIHC cis rs2732480 0.577 rs2634681 chr12:48733084 C/T cg21466736 chr12:48725269 NA 0.71 11.43 0.53 7.95e-26 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs1580019 0.587 rs1597555 chr7:32546118 T/G cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.12 0.44 6.4e-18 Cognitive ability; LIHC cis rs4660306 1.000 rs10736426 chr1:45984353 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.53 6.57 0.33 1.86e-10 Homocysteine levels; LIHC cis rs7769051 0.808 rs1467403 chr6:133089952 T/A cg07930552 chr6:133119739 C6orf192 0.67 6.46 0.33 3.68e-10 Type 2 diabetes nephropathy; LIHC cis rs55665837 1.000 rs2305305 chr11:14540942 C/T cg19336497 chr11:14380999 RRAS2 -0.46 -8.29 -0.41 2.54e-15 Vitamin D levels; LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg21747090 chr2:27597821 SNX17 -0.46 -6.85 -0.35 3.36e-11 Menopause (age at onset); LIHC cis rs4853012 0.941 rs2421752 chr2:74341615 A/G cg19729930 chr2:74357872 NA 0.81 17.19 0.68 3.47e-48 Gestational age at birth (maternal effect); LIHC cis rs72781680 1.000 rs72781631 chr2:24195064 G/A cg08917208 chr2:24149416 ATAD2B 0.85 8.15 0.4 6.94e-15 Lymphocyte counts; LIHC cis rs35110281 0.744 rs230644 chr21:44917183 C/T cg01579765 chr21:45077557 HSF2BP 0.32 5.89 0.3 9.15e-9 Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17340548 chr19:46185070 GIPR -0.41 -6.33 -0.32 7.49e-10 Pancreatic cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26708280 chr2:190649305 PMS1;ORMDL1 0.44 6.23 0.32 1.41e-9 Pancreatic cancer; LIHC trans rs7618501 0.633 rs6446193 chr3:50059758 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.28 -0.45 2.05e-18 Intelligence (multi-trait analysis); LIHC cis rs6442522 0.933 rs7622657 chr3:15411892 C/G cg16303742 chr3:15540471 COLQ -0.34 -5.76 -0.3 1.83e-8 Uric acid levels; LIHC cis rs2952156 0.834 rs903503 chr17:37829571 C/A cg00129232 chr17:37814104 STARD3 -0.54 -10.07 -0.48 4.6e-21 Asthma; LIHC cis rs9733 0.596 rs7529998 chr1:150662531 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.3 0.32 9.39e-10 Tonsillectomy; LIHC cis rs9902453 0.935 rs9911794 chr17:28349466 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs7914558 0.621 rs7896290 chr10:104656015 G/A cg15744005 chr10:104629667 AS3MT -0.35 -7.38 -0.37 1.22e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7412746 0.611 rs11204726 chr1:150743492 T/C cg18016565 chr1:150552671 MCL1 0.54 10.13 0.48 2.88e-21 Melanoma; LIHC cis rs1552244 0.751 rs12715665 chr3:10021601 C/T cg13047869 chr3:10149882 C3orf24 0.41 5.76 0.3 1.87e-8 Alzheimer's disease; LIHC cis rs3096299 0.967 rs28689480 chr16:89460093 T/C cg01788221 chr16:89496183 ANKRD11 -0.39 -6.0 -0.31 4.9e-9 Multiple myeloma (IgH translocation); LIHC cis rs4930561 0.714 rs11228151 chr11:67949371 C/G cg04465784 chr11:67976953 SUV420H1 -0.3 -5.75 -0.3 1.96e-8 Breast cancer in childhood cancer survivors;IgG glycosylation; LIHC cis rs2228479 0.850 rs11646766 chr16:89838578 A/T cg06558623 chr16:89946397 TCF25 0.88 12.21 0.55 1.01e-28 Skin colour saturation; LIHC cis rs7116495 0.609 rs3750907 chr11:71822560 T/C cg26138937 chr11:71823887 C11orf51 1.31 10.43 0.49 2.7e-22 Severe influenza A (H1N1) infection; LIHC cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg06634786 chr22:41940651 POLR3H 0.73 7.56 0.38 3.68e-13 Vitiligo; LIHC cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg19729930 chr2:74357872 NA 0.8 17.45 0.69 3.24e-49 Gestational age at birth (maternal effect); LIHC cis rs1144333 0.655 rs76612182 chr1:76451889 C/T cg03433033 chr1:76189801 ACADM 0.55 7.79 0.39 8.24e-14 Attention function in attention deficit hyperactive disorder; LIHC cis rs2412488 0.893 rs7691892 chr4:54360381 A/G cg22241045 chr4:54363911 LNX1 0.46 7.65 0.38 2.07e-13 DNA methylation (variation); LIHC cis rs4563143 0.514 rs112651366 chr19:29299704 A/T cg14983838 chr19:29218262 NA 0.44 6.34 0.32 7.44e-10 Methadone dose in opioid dependence; LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs10489202 0.909 rs61809580 chr1:168091602 A/C cg17859187 chr1:168147929 TIPRL 0.6 7.64 0.38 2.18e-13 Schizophrenia; LIHC cis rs7546668 1.000 rs4646068 chr1:15828704 T/C cg11706911 chr1:15910989 AGMAT 0.44 6.8 0.35 4.68e-11 Glomerular filtration rate (creatinine); LIHC trans rs116095464 0.558 rs6866632 chr5:264429 C/G cg00938859 chr5:1591904 SDHAP3 0.58 6.86 0.35 3.34e-11 Breast cancer; LIHC cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg22800045 chr5:56110881 MAP3K1 0.66 8.42 0.41 1.05e-15 Initial pursuit acceleration; LIHC cis rs7937890 0.900 rs7118682 chr11:14274550 T/G cg22961513 chr11:14280813 SPON1 0.49 7.64 0.38 2.21e-13 Mitochondrial DNA levels; LIHC cis rs875971 0.895 rs7788984 chr7:65915616 A/G cg18876405 chr7:65276391 NA 0.38 6.86 0.35 3.16e-11 Aortic root size; LIHC cis rs4853012 0.838 rs12619982 chr2:74356022 G/A cg20891558 chr2:74357851 NA 0.82 16.95 0.68 3.17e-47 Gestational age at birth (maternal effect); LIHC cis rs4948275 0.550 rs7904815 chr10:63136612 G/A cg03237606 chr10:63212265 TMEM26 0.33 7.39 0.37 1.11e-12 Night sleep phenotypes; LIHC cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg20607798 chr8:58055168 NA 0.49 6.23 0.32 1.34e-9 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.903 rs12244253 chr10:889320 G/T cg20503657 chr10:835505 NA 1.1 12.95 0.57 1.73e-31 Eosinophil percentage of granulocytes; LIHC cis rs7959452 0.530 rs12811632 chr12:69755003 G/A cg14784868 chr12:69753453 YEATS4 0.95 20.39 0.74 5e-61 Blood protein levels; LIHC cis rs4237845 0.513 rs7134797 chr12:58263852 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.56 7.81 0.39 6.85e-14 Intelligence (multi-trait analysis); LIHC cis rs17685 0.625 rs1639630 chr7:75730499 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.76e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22827060 chr13:30424359 UBL3 0.44 6.44 0.33 3.98e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9902453 1.000 rs4465650 chr17:28396721 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 11.4 0.52 9.72e-26 Coffee consumption (cups per day); LIHC cis rs875971 0.862 rs4718330 chr7:65715243 G/A cg11764359 chr7:65958608 NA -0.82 -13.91 -0.6 3.69e-35 Aortic root size; LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs2303745 0.589 rs891018 chr19:17396761 C/T cg02221750 chr19:17393354 ANKLE1 0.43 6.14 0.32 2.32e-9 Systemic lupus erythematosus; LIHC cis rs11098499 0.954 rs11722872 chr4:120233030 G/C cg09307838 chr4:120376055 NA 0.74 11.18 0.52 5.92e-25 Corneal astigmatism; LIHC cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg21724239 chr8:58056113 NA 0.6 7.39 0.37 1.1e-12 Developmental language disorder (linguistic errors); LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg26939375 chr7:64535504 NA -0.42 -7.22 -0.36 3.32e-12 Calcium levels; LIHC cis rs950169 0.580 rs17598114 chr15:85171317 C/T cg03959625 chr15:84868606 LOC388152 0.43 6.07 0.31 3.43e-9 Schizophrenia; LIHC cis rs611744 0.967 rs686251 chr8:109198907 C/A cg18478394 chr8:109455254 TTC35 0.4 6.89 0.35 2.64e-11 Dupuytren's disease; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg00322698 chr6:41069048 NFYA;LOC221442 0.4 6.24 0.32 1.26e-9 Immature fraction of reticulocytes; LIHC cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg07061783 chr6:25882402 NA 0.67 8.97 0.44 1.99e-17 Blood metabolite levels; LIHC cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg16049864 chr8:95962084 TP53INP1 -0.6 -11.48 -0.53 5.13e-26 Type 2 diabetes; LIHC cis rs12701220 0.655 rs34344742 chr7:1149288 C/G cg04025307 chr7:1156635 C7orf50 0.55 7.33 0.37 1.73e-12 Bronchopulmonary dysplasia; LIHC trans rs72960926 0.744 rs11754468 chr6:74932522 C/T cg07247405 chr1:2484626 LOC115110 0.55 6.58 0.34 1.75e-10 Metabolite levels (MHPG); LIHC cis rs769267 0.965 rs1469712 chr19:19528821 C/A cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.01 0.31 4.78e-9 Tonsillectomy; LIHC cis rs6570726 0.935 rs452552 chr6:145820781 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13821173 chr7:98591120 TRRAP -0.4 -6.06 -0.31 3.67e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.26 -0.61 1.61e-36 Alzheimer's disease; LIHC cis rs1538970 0.774 rs67683090 chr1:45977803 T/G cg05343316 chr1:45956843 TESK2 0.59 8.31 0.41 2.27e-15 Platelet count; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg09033563 chr22:24373618 LOC391322 -0.47 -6.57 -0.33 1.84e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4808199 0.843 rs10402308 chr19:19657500 G/A cg03709012 chr19:19516395 GATAD2A 1.03 16.23 0.66 2.46e-44 Nonalcoholic fatty liver disease; LIHC trans rs6062509 0.839 rs6062298 chr20:62301970 G/A cg01311341 chr22:25575246 KIAA1671 0.43 6.64 0.34 1.27e-10 Prostate cancer; LIHC cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg22105103 chr4:187893119 NA 0.35 8.82 0.43 6.11e-17 Lobe attachment (rater-scored or self-reported); LIHC trans rs35110281 0.659 rs73367822 chr21:45024252 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.47 6.55 0.33 2.11e-10 Mean corpuscular volume; LIHC cis rs4638749 0.677 rs34449318 chr2:108827222 T/C cg25838818 chr2:108905173 SULT1C2 -0.4 -7.0 -0.35 1.37e-11 Blood pressure; LIHC cis rs12477438 0.765 rs6750876 chr2:99679673 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs17666538 0.535 rs1669613 chr8:617565 G/C cg13264159 chr8:625131 ERICH1 -0.62 -6.29 -0.32 9.62e-10 IgG glycosylation; LIHC trans rs17685 0.725 rs6467993 chr7:75719350 G/A cg19862616 chr7:65841803 NCRNA00174 0.91 18.79 0.71 1.31e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs5769765 0.955 rs9616367 chr22:50303515 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.85 -10.47 -0.49 2.03e-22 Schizophrenia; LIHC cis rs9911578 0.741 rs2611776 chr17:56819636 G/T cg12560992 chr17:57184187 TRIM37 0.96 17.17 0.68 4.27e-48 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.520 rs13010904 chr2:99754289 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.26 0.64 1.81e-40 Chronic sinus infection; LIHC cis rs17750015 0.733 rs7506986 chr18:54404558 C/T cg18434998 chr18:54306185 TXNL1 -0.48 -6.74 -0.34 6.5500000000000006e-11 Depression and alcohol dependence; LIHC cis rs6867032 1.000 rs16902321 chr5:2015148 A/G cg26168224 chr5:2018326 NA 0.32 8.06 0.4 1.32e-14 Gut microbiome composition (winter); LIHC cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.21 0.45 3.34e-18 Platelet count; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg18110333 chr6:292329 DUSP22 0.52 6.99 0.35 1.44e-11 Menopause (age at onset); LIHC cis rs6088580 0.634 rs6088508 chr20:33060081 A/G cg08999081 chr20:33150536 PIGU 0.67 13.17 0.58 2.51e-32 Glomerular filtration rate (creatinine); LIHC cis rs56011263 0.687 rs4690292 chr4:703712 A/G cg17689763 chr4:710664 PCGF3 -0.72 -10.12 -0.48 3.23e-21 White blood cell count; LIHC cis rs10751667 0.643 rs7394436 chr11:970373 G/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs1892700 0.730 rs2834232 chr21:34892896 C/T cg14850771 chr21:34775459 IFNGR2 -0.45 -5.98 -0.31 5.51e-9 Educational attainment; LIHC cis rs3736485 0.966 rs17609917 chr15:51911487 G/C cg08986416 chr15:51914746 DMXL2 -0.47 -6.99 -0.35 1.49e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs11098499 0.619 rs28502463 chr4:120257023 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.26 0.41 3.23e-15 Corneal astigmatism; LIHC cis rs13118159 0.778 rs12640984 chr4:1338834 G/A cg13395646 chr4:1353034 KIAA1530 -0.6 -8.3 -0.41 2.43e-15 Longevity; LIHC cis rs546131 0.642 rs579926 chr11:34853155 C/T cg06937548 chr11:34938143 PDHX;APIP 0.58 7.52 0.38 4.95e-13 Lung disease severity in cystic fibrosis; LIHC cis rs35306767 0.903 rs4522091 chr10:874116 G/T cg20503657 chr10:835505 NA 1.08 11.83 0.54 2.63e-27 Eosinophil percentage of granulocytes; LIHC trans rs6563199 0.522 rs7335775 chr13:81370189 C/T cg02732134 chr10:101732382 DNMBP -0.37 -6.6 -0.34 1.59e-10 Height; LIHC cis rs6942756 1.000 rs73472312 chr7:128925217 T/C cg02491457 chr7:128862824 NA -0.64 -9.24 -0.45 2.78e-18 White matter hyperintensity burden; LIHC cis rs116095464 0.558 rs55833259 chr5:286728 G/A cg22496380 chr5:211416 CCDC127 -1.1 -10.33 -0.49 5.84e-22 Breast cancer; LIHC cis rs61990749 0.597 rs2364584 chr14:78152286 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.59 -9.97 -0.47 9.88e-21 Fibroblast growth factor basic levels; LIHC cis rs1419980 0.730 rs116906540 chr12:7751202 A/C cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC trans rs6600671 1.000 rs6600671 chr1:121200490 T/G cg09829573 chr1:144692074 NBPF9 0.39 6.43 0.33 4.27e-10 Hip geometry; LIHC cis rs10426930 0.607 rs877287 chr19:5041989 G/A cg18473234 chr19:5097819 KDM4B 0.57 6.63 0.34 1.33e-10 Monocyte percentage of white cells; LIHC cis rs4919087 0.683 rs7074896 chr10:99071282 T/C cg25902810 chr10:99078978 FRAT1 -0.6 -7.23 -0.36 3.16e-12 Monocyte count; LIHC cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.82 8.36 0.41 1.57e-15 Platelet count; LIHC cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.702 rs12600047 chr16:89831630 G/A cg04013166 chr16:89971882 TCF25 0.5 6.21 0.32 1.51e-9 Skin colour saturation; LIHC trans rs875971 0.545 rs1267814 chr7:66044409 G/A cg26939375 chr7:64535504 NA -0.39 -6.2 -0.32 1.63e-9 Aortic root size; LIHC cis rs35306767 0.715 rs11253539 chr10:1011347 G/A cg20503657 chr10:835505 NA 0.89 8.44 0.42 9.23e-16 Eosinophil percentage of granulocytes; LIHC cis rs7772486 0.875 rs9322044 chr6:146369608 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -6.0 -0.31 5.05e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs783540 0.967 rs1864699 chr15:83323318 A/G cg18393722 chr15:85113863 UBE2QP1 0.39 6.78 0.34 5.17e-11 Schizophrenia; LIHC trans rs526821 0.532 rs578067 chr11:55313690 T/G cg15704280 chr7:45808275 SEPT13 -0.5 -7.63 -0.38 2.31e-13 Pediatric bone mineral density (spine); LIHC cis rs3749237 0.595 rs3870337 chr3:49557095 G/T cg06212747 chr3:49208901 KLHDC8B 0.45 5.92 0.3 7.8e-9 Resting heart rate; LIHC cis rs11190604 1.000 rs2495751 chr10:102327260 A/G cg07080220 chr10:102295463 HIF1AN 0.54 7.33 0.37 1.63e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg05185784 chr16:90016020 DEF8 -0.45 -5.88 -0.3 9.64e-9 Skin colour saturation; LIHC cis rs17412740 1.000 rs41343448 chr8:20271413 A/G cg05315874 chr8:20054693 ATP6V1B2 -0.61 -6.7 -0.34 8.42e-11 Preeclampsia; LIHC cis rs9457247 0.765 rs1322077 chr6:167424293 T/C cg07741184 chr6:167504864 NA 0.32 7.32 0.37 1.75e-12 Crohn's disease; LIHC cis rs600231 0.706 rs11227221 chr11:65319265 T/C cg13974409 chr11:65292307 SCYL1 -0.38 -5.99 -0.31 5.46e-9 Bone mineral density; LIHC cis rs12477438 0.765 rs2309521 chr2:99592069 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.45 -0.49 2.26e-22 Chronic sinus infection; LIHC cis rs7903847 0.642 rs11189174 chr10:99139600 C/G cg08345082 chr10:99160200 RRP12 -0.38 -6.26 -0.32 1.16e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs9942416 0.586 rs111745049 chr5:75037761 T/A cg19683494 chr5:74908142 NA 0.52 5.85 0.3 1.12e-8 Age-related disease endophenotypes; LIHC cis rs5769765 1.000 rs738711 chr22:50282603 A/G cg26441486 chr22:50317300 CRELD2 -0.35 -6.32 -0.32 7.96e-10 Schizophrenia; LIHC cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg15320075 chr8:145703422 NA -0.39 -6.47 -0.33 3.4e-10 Age at first birth; LIHC trans rs6951245 0.554 rs58210047 chr7:1149381 G/A cg13565492 chr6:43139072 SRF -0.8 -7.47 -0.37 6.58e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.7 11.37 0.52 1.23e-25 Height; LIHC cis rs77741769 0.529 rs10849791 chr12:121235280 T/C cg02419362 chr12:121203948 SPPL3 0.33 5.71 0.3 2.42e-8 Mean corpuscular volume; LIHC trans rs1814175 0.817 rs10839401 chr11:49876144 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.66e-12 Height; LIHC cis rs7937682 0.883 rs1784775 chr11:111472460 T/C cg22437258 chr11:111473054 SIK2 0.51 5.74 0.3 2.11e-8 Primary sclerosing cholangitis; LIHC cis rs10744422 1.000 rs12255 chr12:123350204 C/T cg18912006 chr12:123335444 HIP1R -0.62 -7.38 -0.37 1.18e-12 Schizophrenia; LIHC cis rs4668356 0.687 rs16859206 chr2:172043803 A/G cg13882835 chr2:172017928 TLK1 0.44 5.99 0.31 5.25e-9 Cognitive performance; LIHC trans rs561341 0.739 rs6505267 chr17:30225950 A/C cg20587970 chr11:113659929 NA -0.57 -7.21 -0.36 3.69e-12 Hip circumference adjusted for BMI; LIHC cis rs9300255 0.537 rs2682429 chr12:123642955 C/G cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs2524276 1 rs2524276 chr6:31408265 C/A cg15633609 chr6:31324621 HLA-B 0.77 6.2 0.32 1.61e-9 Capecitabine sensitivity; LIHC cis rs4819052 0.788 rs4819051 chr21:46693128 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.26 0.41 3.32e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4919087 0.892 rs2065861 chr10:99004608 C/T cg25902810 chr10:99078978 FRAT1 0.62 9.0 0.44 1.57e-17 Monocyte count; LIHC cis rs8141529 0.664 rs5762861 chr22:29250505 T/G cg15103426 chr22:29168792 CCDC117 0.51 7.95 0.4 2.67e-14 Lymphocyte counts; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg14780466 chr2:20870812 GDF7 0.39 8.77 0.43 8.8e-17 Abdominal aortic aneurysm; LIHC cis rs1577917 0.771 rs9294337 chr6:86248460 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 12.0 0.54 6.38e-28 Response to antipsychotic treatment; LIHC cis rs1348850 0.567 rs3821006 chr2:178537694 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.27 0.41 3.05e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10768122 0.642 rs4756214 chr11:35365938 C/T cg13971030 chr11:35366721 SLC1A2 -0.35 -5.76 -0.3 1.9e-8 Vitiligo; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.91 8.42 0.41 1.01e-15 Platelet count; LIHC cis rs734999 0.967 rs6672381 chr1:2502834 A/G cg18854424 chr1:2615690 NA 0.32 6.75 0.34 6.43e-11 Ulcerative colitis; LIHC cis rs2976388 0.566 rs4736373 chr8:143792357 G/C cg06565975 chr8:143823917 SLURP1 -0.44 -8.04 -0.4 1.44e-14 Urinary tract infection frequency; LIHC cis rs7772486 0.790 rs6570723 chr6:146151230 A/T cg13319975 chr6:146136371 FBXO30 -0.34 -5.78 -0.3 1.7e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs3015497 0.753 rs4643225 chr14:51122205 G/C cg09863266 chr14:51125203 SAV1 -0.43 -6.86 -0.35 3.24e-11 Mean platelet volume; LIHC cis rs4843747 0.518 rs4072777 chr16:88107030 G/A cg00677901 chr16:88017247 BANP 0.52 8.02 0.4 1.74e-14 Menopause (age at onset); LIHC cis rs992157 0.710 rs10169718 chr2:219103580 C/T cg00012203 chr2:219082015 ARPC2 -0.93 -17.04 -0.68 1.48e-47 Colorectal cancer; LIHC trans rs1005277 0.541 rs2472177 chr10:38384015 T/G cg23533926 chr12:111358616 MYL2 -0.33 -6.37 -0.33 6.02e-10 Extrinsic epigenetic age acceleration; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg06085875 chr4:83937413 NA 0.38 6.84 0.35 3.73e-11 Oropharynx cancer; LIHC cis rs600806 0.850 rs10745354 chr1:109931908 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.61 -11.87 -0.54 1.89e-27 Prudent dietary pattern; LIHC cis rs2760061 0.819 rs708111 chr1:228191365 G/A cg01200585 chr1:228362443 C1orf69 0.42 6.44 0.33 4.08e-10 Diastolic blood pressure; LIHC cis rs6503525 0.701 rs28618095 chr17:38109075 T/C cg17344932 chr17:38183730 MED24;SNORD124 -0.5 -7.44 -0.37 8.04e-13 Asthma; LIHC cis rs7216064 1.000 rs12451721 chr17:65939075 G/A cg12091567 chr17:66097778 LOC651250 -0.67 -9.53 -0.46 3.12e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.88 7.96 0.4 2.52e-14 Platelet count; LIHC cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg11663144 chr21:46675770 NA -0.34 -6.32 -0.32 7.99e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10197940 0.710 rs4500942 chr2:152334580 A/G cg19508488 chr2:152266495 RIF1 0.69 10.36 0.49 4.72e-22 Lung cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06363214 chr1:90228963 NA 0.39 6.09 0.31 3.02e-9 Cognitive function; LIHC cis rs35110281 0.600 rs11089092 chr21:45120994 A/C cg21573476 chr21:45109991 RRP1B -0.54 -10.37 -0.49 4.2e-22 Mean corpuscular volume; LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg20607798 chr8:58055168 NA 0.63 8.0 0.4 1.89e-14 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09698166 chr20:21106763 PLK1S1 0.49 7.96 0.4 2.48e-14 Pancreatic cancer; LIHC cis rs12079745 0.793 rs78266198 chr1:169346615 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 2.01e-11 QT interval; LIHC cis rs9583531 0.600 rs6492303 chr13:111356800 G/A cg15841412 chr13:111365552 ING1 0.47 5.93 0.31 7.54e-9 Coronary artery disease; LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg21724239 chr8:58056113 NA -0.56 -7.48 -0.38 6.26e-13 Developmental language disorder (linguistic errors); LIHC cis rs3768617 0.510 rs6666259 chr1:183102855 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.45 0.49 2.24e-22 Fuchs's corneal dystrophy; LIHC cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs929354 0.772 rs2366214 chr7:156992461 A/G cg05182265 chr7:156933206 UBE3C -0.32 -5.99 -0.31 5.43e-9 Body mass index; LIHC cis rs644799 0.542 rs10831415 chr11:95466159 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.75 11.58 0.53 2.17e-26 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs736408 0.583 rs2710323 chr3:52815905 T/C cg18404041 chr3:52824283 ITIH1 -0.55 -9.06 -0.44 1.06e-17 Bipolar disorder; LIHC cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg21724239 chr8:58056113 NA 0.49 6.4 0.33 5.14e-10 Developmental language disorder (linguistic errors); LIHC cis rs11148252 0.774 rs9536066 chr13:52983981 A/G cg00495681 chr13:53174319 NA 0.41 6.85 0.35 3.51e-11 Lewy body disease; LIHC cis rs9916302 0.851 rs11078904 chr17:37650569 G/A cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg05484376 chr2:27715224 FNDC4 0.38 6.42 0.33 4.69e-10 Menopause (age at onset); LIHC cis rs950169 0.922 rs11630507 chr15:85095725 A/G cg17507749 chr15:85114479 UBE2QP1 0.76 8.96 0.44 2.1e-17 Schizophrenia; LIHC cis rs12594515 1.000 rs6493176 chr15:45990026 A/G cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC cis rs79149102 0.579 rs7166105 chr15:75343942 A/G cg17294928 chr15:75287854 SCAMP5 0.51 6.51 0.33 2.66e-10 Lung cancer; LIHC cis rs7789940 0.951 rs7787526 chr7:75947553 C/T cg10167463 chr7:75959203 YWHAG -0.45 -6.98 -0.35 1.56e-11 Multiple sclerosis; LIHC cis rs17152411 0.895 rs66531168 chr10:126586908 T/A cg07906193 chr10:126599966 NA 0.44 6.89 0.35 2.74e-11 Height; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.21e-14 Prudent dietary pattern; LIHC cis rs61712019 0.563 rs11885676 chr2:77732482 T/C cg11252801 chr2:77748917 LRRTM4 0.46 6.36 0.33 6.44e-10 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14208070 chr17:4685804 TM4SF5 0.41 6.2 0.32 1.66e-9 Cognitive function; LIHC trans rs8033655 0.925 rs7180182 chr15:50310295 A/G cg10099229 chr12:6960622 USP5;CDCA3 0.42 6.08 0.31 3.2e-9 Skin pigmentation; LIHC cis rs60871478 0.636 rs10245785 chr7:894422 T/C cg05535760 chr7:792225 HEATR2 -0.81 -6.59 -0.34 1.63e-10 Cerebrospinal P-tau181p levels; LIHC cis rs7408868 0.764 rs45504393 chr19:15277010 A/G cg14696996 chr19:15285081 NOTCH3 0.53 7.1 0.36 7.41e-12 Pulse pressure; LIHC cis rs11190604 0.945 rs11190573 chr10:102233172 T/C cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9902453 0.817 rs7217961 chr17:28403112 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.73 -0.6 1.82e-34 Coffee consumption (cups per day); LIHC cis rs950169 0.580 rs11630887 chr15:85193015 A/T cg17507749 chr15:85114479 UBE2QP1 0.68 7.89 0.39 4.17e-14 Schizophrenia; LIHC cis rs881375 0.967 rs2270231 chr9:123650982 C/G cg14580859 chr9:123691850 NA 0.38 6.55 0.33 2.08e-10 Rheumatoid arthritis; LIHC cis rs743757 0.938 rs2236981 chr3:50488845 A/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.4 0.37 1.07e-12 Diastolic blood pressure; LIHC trans rs35110281 0.805 rs162402 chr21:44963418 G/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.22 0.32 1.48e-9 Mean corpuscular volume; LIHC cis rs35883536 0.626 rs11799819 chr1:101049382 G/A cg14515779 chr1:101123966 NA 0.49 6.79 0.34 4.86e-11 Monocyte count; LIHC cis rs2304069 0.913 rs7734382 chr5:149383241 A/T cg12661370 chr5:149340060 SLC26A2 0.51 6.17 0.32 1.92e-9 HIV-1 control; LIHC cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg17554472 chr22:41940697 POLR3H 0.56 6.23 0.32 1.34e-9 Vitiligo; LIHC cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg11645453 chr3:52864694 ITIH4 0.22 5.74 0.3 2.13e-8 Bipolar disorder; LIHC cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg12310025 chr6:25882481 NA -0.52 -6.61 -0.34 1.44e-10 Intelligence (multi-trait analysis); LIHC cis rs2268241 0.938 rs11088251 chr21:34770810 A/C cg14850771 chr21:34775459 IFNGR2 0.85 13.35 0.59 5.11e-33 Obesity-related traits; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg26338869 chr17:61819248 STRADA 0.6 8.61 0.42 2.73e-16 Prudent dietary pattern; LIHC cis rs7647973 0.961 rs10154992 chr3:49276077 C/T cg07636037 chr3:49044803 WDR6 0.51 6.5 0.33 2.78e-10 Menarche (age at onset); LIHC cis rs2573652 1.000 rs2581363 chr15:100513364 G/A cg09918751 chr15:100517450 ADAMTS17 -0.77 -13.37 -0.59 4.39e-33 Height; LIHC trans rs877282 1.000 rs877281 chr10:771557 T/G cg22713356 chr15:30763199 NA 1.42 12.92 0.57 2.22e-31 Uric acid levels; LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg27432699 chr2:27873401 GPN1 -0.5 -7.17 -0.36 4.62e-12 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15655138 chr6:37139981 PIM1 0.48 6.82 0.35 4.2e-11 Pancreatic cancer; LIHC cis rs3764563 0.735 rs62106282 chr19:15727124 T/C cg20725493 chr19:15740067 CYP4F8 -0.68 -5.75 -0.3 2e-8 Inflammatory biomarkers; LIHC cis rs78545713 0.892 rs76182849 chr6:26257950 C/T cg16070018 chr6:26224392 HIST1H3E 0.66 7.25 0.36 2.85e-12 Iron status biomarkers (total iron binding capacity); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12317515 chr5:74063363 GFM2;NSA2 0.44 6.39 0.33 5.54e-10 Pancreatic cancer; LIHC cis rs1018836 0.631 rs61276517 chr8:91474406 A/G cg16814680 chr8:91681699 NA -0.37 -6.08 -0.31 3.25e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs778371 0.752 rs283487 chr2:233644011 A/G cg08000102 chr2:233561755 GIGYF2 0.77 9.28 0.45 2.04e-18 Schizophrenia; LIHC cis rs34779708 0.966 rs11592567 chr10:35409369 C/T cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs416603 0.967 rs7191538 chr16:11363389 C/G cg00044050 chr16:11439710 C16orf75 -0.42 -5.9 -0.3 8.55e-9 Type 1 diabetes; LIHC cis rs2250402 0.510 rs6492926 chr15:40325829 T/G cg01081584 chr15:40268610 EIF2AK4 -0.53 -6.19 -0.32 1.69e-9 Corneal curvature; LIHC cis rs11190604 1.000 rs2495758 chr10:102321900 C/G cg07080220 chr10:102295463 HIF1AN 0.53 7.18 0.36 4.49e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7412746 0.611 rs2280627 chr1:150935872 A/G cg15448220 chr1:150897856 SETDB1 0.39 6.15 0.32 2.15e-9 Melanoma; LIHC cis rs9303401 0.659 rs66514313 chr17:56714057 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs1538970 0.851 rs61788285 chr1:45919234 A/C cg05343316 chr1:45956843 TESK2 0.6 8.69 0.43 1.5e-16 Platelet count; LIHC cis rs798554 0.796 rs2158694 chr7:2863443 T/G cg13628971 chr7:2884303 GNA12 0.54 7.68 0.38 1.71e-13 Height; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg15979172 chr19:15490570 AKAP8 0.47 6.28 0.32 1.01e-9 Hepatitis; LIHC trans rs9302065 0.565 rs2992910 chr13:95962216 T/A cg19955956 chr7:72299837 SBDSP;TYW1B 0.35 6.48 0.33 3.24e-10 Blood metabolite levels; LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg07002622 chr6:118822466 C6orf204;BRD7P3 0.5 5.94 0.31 6.83e-9 Diastolic blood pressure; LIHC cis rs9611519 0.929 rs9611469 chr22:41433319 T/C cg03806693 chr22:41940476 POLR3H -0.69 -7.78 -0.39 8.92e-14 Neuroticism; LIHC cis rs2562456 0.617 rs34203148 chr19:21773545 T/A cg23367146 chr19:21773418 NA 0.38 5.79 0.3 1.56e-8 Pain; LIHC trans rs12478296 1.000 rs7603984 chr2:243047294 A/G cg01596870 chr19:55963115 NA -0.63 -7.52 -0.38 4.78e-13 Obesity-related traits; LIHC cis rs7927771 0.864 rs3781627 chr11:47441472 T/A cg18512352 chr11:47633146 NA 0.28 6.19 0.32 1.72e-9 Subjective well-being; LIHC cis rs1707322 0.896 rs785518 chr1:46568422 A/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.73 -0.34 7.29e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2180341 0.751 rs9388553 chr6:127574044 A/G cg27446573 chr6:127587934 RNF146 0.72 10.9 0.51 6.07e-24 Breast cancer; LIHC cis rs6964587 0.869 rs10250641 chr7:91490746 C/T cg17063962 chr7:91808500 NA 0.96 17.77 0.69 1.73e-50 Breast cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15708001 chr12:54673887 CBX5;HNRNPA1;HNRPA1L-2 0.33 6.09 0.31 3.1e-9 Calcium levels; LIHC cis rs1023500 0.573 rs133374 chr22:42465941 G/A cg00645731 chr22:42541494 CYP2D7P1 0.39 6.23 0.32 1.37e-9 Schizophrenia; LIHC cis rs6500602 0.727 rs6500607 chr16:4503631 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 6.13 0.31 2.49e-9 Schizophrenia; LIHC cis rs4474465 0.850 rs7936232 chr11:78266602 A/G cg27205649 chr11:78285834 NARS2 0.46 7.13 0.36 5.96e-12 Alzheimer's disease (survival time); LIHC cis rs11758351 0.518 rs78871852 chr6:26221566 A/T cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs7903847 0.620 rs9787454 chr10:99155561 A/T cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs3823572 0.564 rs2953618 chr7:133672476 G/C cg03336402 chr7:133662267 EXOC4 -0.5 -5.71 -0.3 2.41e-8 Intelligence (multi-trait analysis); LIHC cis rs7552404 0.961 rs211710 chr1:76109038 G/A cg22875332 chr1:76189707 ACADM -0.48 -6.98 -0.35 1.56e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs780096 0.526 rs7602534 chr2:27592423 C/T cg27432699 chr2:27873401 GPN1 -0.5 -7.17 -0.36 4.62e-12 Total body bone mineral density; LIHC cis rs2637266 1.000 rs7474960 chr10:78359021 C/T cg18941641 chr10:78392320 NA 0.29 6.21 0.32 1.55e-9 Pulmonary function; LIHC cis rs2243480 1.000 rs2243480 chr7:65599196 C/T cg05590025 chr7:65112418 INTS4L2 -0.56 -5.99 -0.31 5.28e-9 Diabetic kidney disease; LIHC cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg00106254 chr7:1943704 MAD1L1 -0.4 -6.45 -0.33 3.79e-10 Schizophrenia; LIHC cis rs13392177 0.672 rs1877715 chr2:219052546 C/T cg00012203 chr2:219082015 ARPC2 0.73 10.55 0.5 1.01e-22 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg14004847 chr7:1930337 MAD1L1 -0.42 -5.95 -0.31 6.62e-9 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs700651 0.789 rs892514 chr2:198905270 T/C cg00792783 chr2:198669748 PLCL1 0.46 6.55 0.33 2.06e-10 Intracranial aneurysm; LIHC cis rs2292096 1.000 rs35045998 chr1:200719186 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.12 -0.31 2.57e-9 Epilepsy; LIHC cis rs6762 0.692 rs5030778 chr11:836008 T/C cg15787769 chr11:842744 TSPAN4;POLR2L -0.6 -7.31 -0.37 1.95e-12 Mean platelet volume; LIHC cis rs743757 1.000 rs2236957 chr3:50440426 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.64 0.38 2.23e-13 Diastolic blood pressure; LIHC cis rs28374715 0.662 rs28587487 chr15:41495460 C/T cg18705301 chr15:41695430 NDUFAF1 -0.88 -9.72 -0.47 7.19e-20 Ulcerative colitis; LIHC cis rs6952808 0.594 rs3778969 chr7:2139990 A/G cg21782813 chr7:2030301 MAD1L1 -0.38 -6.51 -0.33 2.66e-10 Bipolar disorder and schizophrenia; LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.52 -0.38 4.85e-13 Lymphocyte counts; LIHC cis rs6951245 0.832 rs10266519 chr7:1142977 C/T cg22907277 chr7:1156413 C7orf50 0.77 6.15 0.32 2.21e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6547741 0.935 rs12714204 chr2:27787540 T/C cg27432699 chr2:27873401 GPN1 0.73 11.78 0.54 3.98e-27 Oral cavity cancer; LIHC cis rs6988636 0.901 rs62521825 chr8:124185786 C/A cg15893493 chr8:124194847 FAM83A 0.89 8.3 0.41 2.48e-15 Urinary uromodulin levels; LIHC cis rs13108904 0.539 rs13140926 chr4:1340939 G/A cg13395646 chr4:1353034 KIAA1530 -0.86 -13.02 -0.58 9.33e-32 Obesity-related traits; LIHC trans rs7618501 0.521 rs3733134 chr3:49939503 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.46 6.84 0.35 3.63e-11 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.666 rs4074235 chr11:977511 C/G ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs11031096 0.535 rs10767886 chr11:4218391 T/C cg18678763 chr11:4115507 RRM1 -0.42 -6.28 -0.32 1.03e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs903552 0.673 rs4965878 chr15:102009589 C/T cg04789225 chr15:102009795 PCSK6 -0.45 -5.84 -0.3 1.19e-8 Diabetic kidney disease; LIHC cis rs3540 0.597 rs4932346 chr15:91048991 T/C cg22089800 chr15:90895588 ZNF774 -0.59 -8.18 -0.4 5.52e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.54e-26 Alzheimer's disease; LIHC cis rs847649 1.000 rs9718453 chr7:102594976 T/G cg18108683 chr7:102477205 FBXL13 0.48 7.5 0.38 5.45e-13 Morning vs. evening chronotype; LIHC cis rs1728785 0.818 rs1814299 chr16:68581332 G/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs67981189 0.574 rs2526848 chr14:71419742 T/C cg15816911 chr14:71606274 NA -0.42 -6.67 -0.34 1.03e-10 Schizophrenia; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs240764 0.817 rs12201852 chr6:101149576 T/C cg09795085 chr6:101329169 ASCC3 -0.51 -7.0 -0.35 1.33e-11 Neuroticism; LIHC cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg13397359 chr6:42928475 GNMT 0.47 6.59 0.34 1.63e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2204008 0.744 rs11495519 chr12:38060546 C/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs17685 0.725 rs7795291 chr7:75725206 C/A cg01364799 chr7:75623366 TMEM120A -0.47 -7.13 -0.36 5.84e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs780096 0.527 rs12471703 chr2:27738854 C/T cg22903471 chr2:27725779 GCKR -0.54 -9.16 -0.44 4.72e-18 Total body bone mineral density; LIHC cis rs1801251 1.000 rs7558609 chr2:233700379 C/T cg08000102 chr2:233561755 GIGYF2 0.77 11.56 0.53 2.67e-26 Coronary artery disease; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg10150615 chr22:24372951 LOC391322 -0.56 -8.31 -0.41 2.21e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs5015933 0.966 rs1965342 chr9:128133661 T/A cg14078157 chr9:128172775 NA -0.38 -6.58 -0.34 1.79e-10 Body mass index; LIHC cis rs7312774 0.748 rs10492211 chr12:107298213 T/C cg16260113 chr12:107380972 MTERFD3 0.75 9.73 0.47 6.53e-20 Severe influenza A (H1N1) infection; LIHC cis rs9628987 0.569 rs3765972 chr1:8425798 C/T cg20416874 chr1:8611966 RERE 0.49 5.96 0.31 6.22e-9 Breast cancer; LIHC cis rs7772486 0.738 rs9485039 chr6:146319387 C/T cg13319975 chr6:146136371 FBXO30 -0.43 -6.91 -0.35 2.41e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.894 rs7572603 chr2:61552145 C/G cg14146966 chr2:61757674 XPO1 -0.43 -7.19 -0.36 4.17e-12 Tuberculosis; LIHC cis rs9912789 0.807 rs9896850 chr17:79191726 C/T cg09314803 chr17:79180344 AZI1 -0.41 -7.22 -0.36 3.32e-12 Frontotemporal dementia; LIHC cis rs4819052 0.851 rs4819041 chr21:46659955 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.66 10.32 0.49 6.35e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11718455 0.582 rs6763436 chr3:43913653 A/G cg08738300 chr3:44038990 NA -0.41 -6.94 -0.35 1.96e-11 Coronary artery disease; LIHC cis rs4803468 0.967 rs13345590 chr19:41886455 T/G cg09537434 chr19:41945824 ATP5SL -1.0 -20.44 -0.74 2.99e-61 Height; LIHC cis rs6582630 0.615 rs10880642 chr12:38554152 A/G cg26384229 chr12:38710491 ALG10B -0.42 -6.29 -0.32 9.84e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs801193 0.660 rs1016265 chr7:66214567 C/T cg18252515 chr7:66147081 NA -0.44 -6.39 -0.33 5.48e-10 Aortic root size; LIHC cis rs6952808 0.729 rs35797753 chr7:1954914 G/A cg04267008 chr7:1944627 MAD1L1 -0.71 -11.16 -0.52 7.35e-25 Bipolar disorder and schizophrenia; LIHC cis rs8017423 0.935 rs9944124 chr14:90791501 T/C cg14092571 chr14:90743983 NA -0.42 -6.77 -0.34 5.53e-11 Mortality in heart failure; LIHC cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg07636037 chr3:49044803 WDR6 0.77 13.15 0.58 2.9e-32 Menarche (age at onset); LIHC cis rs4713118 0.869 rs9366700 chr6:27696951 C/T cg20933634 chr6:27740509 NA 0.47 6.24 0.32 1.28e-9 Parkinson's disease; LIHC cis rs7106204 0.514 rs1443043 chr11:24251991 A/G ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.24e-27 Response to Homoharringtonine (cytotoxicity); LIHC cis rs10927875 1.000 rs3979179 chr1:16306846 A/G cg21385522 chr1:16154831 NA 0.91 11.51 0.53 4e-26 Dilated cardiomyopathy; LIHC cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg18654377 chr3:49208889 KLHDC8B -0.5 -5.93 -0.31 7.29e-9 Menarche (age at onset); LIHC cis rs60871478 0.787 rs4720928 chr7:808002 T/C cg04727924 chr7:799746 HEATR2 -0.58 -8.62 -0.42 2.51e-16 Cerebrospinal P-tau181p levels; LIHC cis rs2033711 0.622 rs975947 chr19:58898193 C/T cg00825309 chr19:58991885 ZNF446 -0.41 -6.0 -0.31 5e-9 Uric acid clearance; LIHC cis rs6547741 1.000 rs1528404 chr2:27846603 C/T cg27432699 chr2:27873401 GPN1 -0.78 -12.79 -0.57 6.97e-31 Oral cavity cancer; LIHC cis rs921968 0.643 rs611203 chr2:219472325 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.3 0.32 9.1e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg13393036 chr8:95962371 TP53INP1 -0.4 -9.11 -0.44 6.82e-18 Type 2 diabetes; LIHC cis rs7772486 0.686 rs1569540 chr6:146069112 A/G cg23711669 chr6:146136114 FBXO30 -0.64 -11.6 -0.53 1.84e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2806561 0.514 rs10917360 chr1:23539010 C/T cg19743168 chr1:23544995 NA 0.41 6.34 0.32 7.39e-10 Height; LIHC cis rs9649213 0.593 rs10808107 chr7:97951671 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs796364 0.664 rs3106089 chr2:200884615 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.71 7.82 0.39 6.76e-14 Schizophrenia; LIHC cis rs1256061 0.624 rs1152578 chr14:64697037 T/C cg23250157 chr14:64679961 SYNE2 0.42 6.03 0.31 4.21e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg09222892 chr1:25734099 RHCE -0.42 -7.65 -0.38 2.1e-13 Erythrocyte sedimentation rate; LIHC cis rs9916302 0.904 rs9905432 chr17:37555918 C/A cg00129232 chr17:37814104 STARD3 0.4 6.33 0.32 7.78e-10 Glomerular filtration rate (creatinine); LIHC cis rs1144333 0.655 rs75578876 chr1:76395586 A/C cg10523679 chr1:76189770 ACADM 0.47 6.36 0.33 6.47e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg03264133 chr6:25882463 NA -0.62 -8.73 -0.43 1.12e-16 Blood metabolite levels; LIHC cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2569991 0.636 rs361221 chr3:12922767 A/C cg22481960 chr3:13008800 IQSEC1 0.4 6.88 0.35 2.83e-11 Periodontitis (DPAL); LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg26338869 chr17:61819248 STRADA 0.58 8.49 0.42 6.43e-16 Prudent dietary pattern; LIHC cis rs208520 0.754 rs12204635 chr6:66740779 C/A cg07460842 chr6:66804631 NA 0.78 9.07 0.44 9.76e-18 Exhaled nitric oxide output; LIHC trans rs4650994 0.507 rs56229230 chr1:178526563 G/A cg05059571 chr16:84539110 KIAA1609 -0.46 -7.56 -0.38 3.67e-13 HDL cholesterol levels;HDL cholesterol; LIHC trans rs6934970 1.000 rs28510827 chr6:113101492 T/A cg09308777 chr6:169852575 NA 0.6 6.26 0.32 1.13e-9 Bipolar disorder (body mass index interaction); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16256065 chr11:68216328 LRP5 0.42 6.26 0.32 1.16e-9 Longevity; LIHC cis rs6062302 0.522 rs6090476 chr20:62248001 G/A cg06363034 chr20:62225388 GMEB2 -0.45 -7.71 -0.38 1.4e-13 Glioblastoma; LIHC trans rs1994135 0.630 rs11052757 chr12:33719879 A/G cg26384229 chr12:38710491 ALG10B 0.48 6.45 0.33 3.84e-10 Resting heart rate; LIHC cis rs10751667 0.666 rs6597962 chr11:976351 C/T ch.11.42038R chr11:967971 AP2A2 0.55 10.03 0.48 6.14e-21 Alzheimer's disease (late onset); LIHC cis rs910316 0.737 rs2098251 chr14:75492696 G/A cg11812906 chr14:75593930 NEK9 0.74 13.64 0.59 3.84e-34 Height; LIHC cis rs1577917 0.740 rs9344533 chr6:86236188 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.48 9.3 0.45 1.66e-18 Response to antipsychotic treatment; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.23 0.81 4.46e-80 Prudent dietary pattern; LIHC cis rs57221529 0.766 rs72703065 chr5:588123 C/A cg09021430 chr5:549028 NA -0.44 -8.65 -0.42 1.97e-16 Lung disease severity in cystic fibrosis; LIHC cis rs6912958 0.559 rs451829 chr6:88041919 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.96 0.51 3.56e-24 Monocyte percentage of white cells; LIHC cis rs6450176 0.638 rs16881969 chr5:53300748 A/G ch.5.1024479R chr5:53302184 ARL15 0.94 16.44 0.66 3.8e-45 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1707322 0.647 rs6686944 chr1:46156308 G/T cg06784218 chr1:46089804 CCDC17 0.42 7.69 0.38 1.56e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg11618577 chr2:27665543 KRTCAP3 -0.43 -6.01 -0.31 4.75e-9 Total body bone mineral density; LIHC cis rs2153535 0.601 rs7741024 chr6:8530313 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.5 0.53 4.42e-26 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05246190 chr22:50330022 NA 0.47 6.23 0.32 1.4e-9 Lung function (FEV1/FVC); LIHC cis rs2737618 0.674 rs2260033 chr1:200086074 G/A cg21825944 chr1:200113062 NR5A2 -0.49 -8.34 -0.41 1.83e-15 Uric acid levels; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg01171360 chr6:293285 DUSP22 -0.46 -6.66 -0.34 1.11e-10 Menopause (age at onset); LIHC cis rs17401966 0.931 rs2276100 chr1:10394536 C/G cg19773385 chr1:10388646 KIF1B -0.39 -6.88 -0.35 2.85e-11 Hepatocellular carcinoma; LIHC cis rs151997 0.671 rs493507 chr5:50219675 G/T cg06027927 chr5:50259733 NA -0.43 -6.4 -0.33 5.23e-10 Callous-unemotional behaviour; LIHC trans rs804280 0.662 rs11250164 chr8:11610686 C/T cg19442470 chr8:27470225 CLU 0.35 6.22 0.32 1.47e-9 Myopia (pathological); LIHC cis rs7833790 0.636 rs12544174 chr8:82731477 G/A cg27398817 chr8:82754497 SNX16 -0.32 -5.85 -0.3 1.14e-8 Diastolic blood pressure; LIHC cis rs10504073 0.584 rs55795863 chr8:49898055 A/G cg00325661 chr8:49890786 NA 0.38 9.04 0.44 1.22e-17 Blood metabolite ratios; LIHC cis rs9372253 0.934 rs9320327 chr6:110715194 T/A cg19196401 chr6:110721138 DDO -0.32 -6.38 -0.33 5.68e-10 Platelet distribution width; LIHC cis rs8060686 0.641 rs7201742 chr16:68099821 T/G cg09835421 chr16:68378352 PRMT7 -0.49 -5.98 -0.31 5.59e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs17125944 0.686 rs7143400 chr14:53324891 A/C cg00686598 chr14:53173677 PSMC6 -0.83 -9.32 -0.45 1.45e-18 Alzheimer's disease (late onset); LIHC cis rs2370759 1.000 rs2225152 chr10:32574759 T/C cg18270830 chr10:32634957 EPC1 0.53 6.44 0.33 4.04e-10 Sexual dysfunction (female); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26434225 chr8:80942688 MRPS28 0.54 8.26 0.41 3.34e-15 Cognitive function; LIHC cis rs11628318 0.614 rs4906254 chr14:103209153 C/T cg23461800 chr14:103021989 NA -0.39 -5.86 -0.3 1.12e-8 Platelet count; LIHC cis rs17685 0.753 rs2302438 chr7:75677065 C/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.23e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7224737 1.000 rs11079034 chr17:40288890 G/A cg00647820 chr17:40259828 DHX58 -0.28 -5.83 -0.3 1.28e-8 Fibrinogen levels; LIHC cis rs3806843 0.838 rs2563289 chr5:140122766 T/A cg19875535 chr5:140030758 IK -0.37 -6.2 -0.32 1.67e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10911232 0.507 rs4397624 chr1:183053131 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Hypertriglyceridemia; LIHC trans rs9217 0.776 rs11650977 chr17:7392341 A/G cg08566640 chr11:64091735 NA -0.42 -7.33 -0.37 1.73e-12 Height; LIHC cis rs11785400 1.000 rs4736342 chr8:143735190 A/G cg10596483 chr8:143751796 JRK 0.53 8.72 0.43 1.25e-16 Schizophrenia; LIHC cis rs1008375 0.933 rs4698637 chr4:17632843 A/T cg16339924 chr4:17578868 LAP3 0.55 7.36 0.37 1.38e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs877282 1.000 rs12219807 chr10:772870 A/C cg22713356 chr15:30763199 NA 1.23 10.89 0.51 6.83e-24 Uric acid levels; LIHC cis rs6964587 0.967 rs55801687 chr7:91762629 C/A cg17063962 chr7:91808500 NA 1.02 19.69 0.73 3.16e-58 Breast cancer; LIHC trans rs57221529 0.766 rs17563576 chr5:560476 A/G cg25482853 chr8:67687455 SGK3 0.67 6.66 0.34 1.09e-10 Lung disease severity in cystic fibrosis; LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.69 11.32 0.52 1.85e-25 Prudent dietary pattern; LIHC trans rs7022054 0.502 rs2770771 chr9:7216426 G/A cg26740341 chr6:22874184 NA 0.27 6.14 0.32 2.3e-9 Schizophrenia; LIHC cis rs1018836 0.608 rs12679836 chr8:91465287 A/G cg16814680 chr8:91681699 NA -0.35 -5.76 -0.3 1.9e-8 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1506636 1.000 rs656425 chr7:123424525 A/C cg03229431 chr7:123269106 ASB15 0.6 11.91 0.54 1.36e-27 Plateletcrit;Platelet count; LIHC cis rs7534824 0.582 rs61780297 chr1:101400855 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.65 0.38 2.07e-13 Refractive astigmatism; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg24531977 chr5:56204891 C5orf35 -0.69 -9.92 -0.47 1.47e-20 Initial pursuit acceleration; LIHC cis rs765787 0.530 rs4775832 chr15:45534828 A/G cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs9517313 0.551 rs2274051 chr13:99091634 A/G cg07423050 chr13:99094983 FARP1 0.61 11.61 0.53 1.75e-26 Neuroticism; LIHC cis rs68170813 0.559 rs58663672 chr7:106949444 T/C cg02696742 chr7:106810147 HBP1 -0.52 -6.11 -0.31 2.76e-9 Coronary artery disease; LIHC cis rs11758351 0.660 rs16891446 chr6:26226996 A/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg10755058 chr3:40428713 ENTPD3 0.42 7.12 0.36 6.3e-12 Renal cell carcinoma; LIHC cis rs7772486 0.776 rs4316025 chr6:146238032 C/T cg23711669 chr6:146136114 FBXO30 -0.59 -10.43 -0.49 2.65e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6504950 0.720 rs7216138 chr17:52995664 G/A cg10237252 chr17:52977213 TOM1L1 -0.36 -6.32 -0.32 8.02e-10 Breast cancer; LIHC cis rs6964587 0.967 rs10429103 chr7:91598443 T/A cg17063962 chr7:91808500 NA 1.01 19.32 0.72 9.73e-57 Breast cancer; LIHC cis rs7216064 0.861 rs62084252 chr17:65879578 G/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.6 -0.46 1.73e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -6.0 -0.31 5.02e-9 Bipolar disorder and schizophrenia; LIHC cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg22442454 chr1:209979470 IRF6 0.4 5.94 0.31 7.07e-9 Cleft lip with or without cleft palate; LIHC cis rs9868809 0.881 rs2276850 chr3:48669648 G/A cg07636037 chr3:49044803 WDR6 -0.55 -6.39 -0.33 5.38e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs6942756 0.744 rs2718088 chr7:128927020 C/A cg02491457 chr7:128862824 NA 0.57 8.46 0.42 7.85e-16 White matter hyperintensity burden; LIHC cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg00684032 chr4:1343700 KIAA1530 0.52 7.54 0.38 4.36e-13 Obesity-related traits; LIHC cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs6570726 0.846 rs6919684 chr6:145883801 A/G cg23711669 chr6:146136114 FBXO30 0.65 11.61 0.53 1.74e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9543976 1.000 rs1535724 chr13:76183273 G/C cg01531495 chr13:76123901 UCHL3 0.48 5.76 0.3 1.87e-8 Diabetic retinopathy; LIHC trans rs2749592 0.531 rs1208559 chr10:38221370 T/C cg04469686 chr1:162760199 HSD17B7 0.38 6.18 0.32 1.83e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs35883536 1.000 rs964906 chr1:101087479 G/A cg14515779 chr1:101123966 NA -0.67 -12.44 -0.56 1.47e-29 Monocyte count; LIHC cis rs55702914 0.712 rs12619296 chr2:198148767 A/G cg10820045 chr2:198174542 NA -0.37 -5.75 -0.3 2.01e-8 Major depression and alcohol dependence; LIHC cis rs9486719 0.947 rs6916232 chr6:96985959 A/T cg06623918 chr6:96969491 KIAA0776 0.68 6.81 0.35 4.52e-11 Migraine;Coronary artery disease; LIHC cis rs8017423 0.967 rs11628881 chr14:90713833 C/T cg14092571 chr14:90743983 NA -0.38 -6.06 -0.31 3.5e-9 Mortality in heart failure; LIHC cis rs6120849 0.707 rs6120799 chr20:33614955 T/C cg24642439 chr20:33292090 TP53INP2 0.65 7.0 0.35 1.36e-11 Protein C levels; LIHC cis rs826838 0.935 rs1719855 chr12:39127242 C/T cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.4e-8 Heart rate; LIHC cis rs12493885 0.818 rs7641039 chr3:153768638 A/C cg10247383 chr3:153839028 SGEF -0.65 -6.1 -0.31 2.89e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs3780486 0.846 rs4584234 chr9:33147479 G/A cg13443165 chr9:33130375 B4GALT1 -0.34 -5.94 -0.31 6.93e-9 IgG glycosylation; LIHC cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg05890377 chr2:74357713 NA 0.64 12.98 0.57 1.4e-31 Gestational age at birth (maternal effect); LIHC cis rs7552404 1.000 rs7513559 chr1:76173744 A/G cg03433033 chr1:76189801 ACADM 0.67 9.35 0.45 1.16e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7520050 0.966 rs785471 chr1:46518677 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 6.02 0.31 4.42e-9 Red blood cell count;Reticulocyte count; LIHC cis rs600806 0.813 rs6664236 chr1:109986672 C/A cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.44 -0.37 8.13e-13 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.692 rs34272342 chr15:77012276 A/C cg23625390 chr15:77176239 SCAPER 0.36 5.95 0.31 6.48e-9 Blood metabolite levels; LIHC cis rs9309473 1.000 rs2421555 chr2:73816955 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.85 -0.35 3.48e-11 Metabolite levels; LIHC cis rs769267 1.000 rs12985655 chr19:19442434 G/A cg03709012 chr19:19516395 GATAD2A -0.92 -16.02 -0.65 1.72e-43 Tonsillectomy; LIHC cis rs17125944 0.686 rs55685925 chr14:53334546 A/G cg00686598 chr14:53173677 PSMC6 -0.8 -9.28 -0.45 1.93e-18 Alzheimer's disease (late onset); LIHC cis rs67460515 0.892 rs7648279 chr3:160979646 G/A cg03342759 chr3:160939853 NMD3 -0.66 -10.12 -0.48 3.05e-21 Parkinson's disease; LIHC cis rs60871478 1.000 rs35488064 chr7:812722 G/C cg05535760 chr7:792225 HEATR2 0.78 10.87 0.51 7.51e-24 Cerebrospinal P-tau181p levels; LIHC cis rs651907 0.557 rs13077925 chr3:101488181 T/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.45 0.53 6.42e-26 Colorectal cancer; LIHC cis rs7106204 0.800 rs7120940 chr11:24236485 C/A ch.11.24196551F chr11:24239977 NA 0.81 11.5 0.53 4.29e-26 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2836950 0.565 rs2836942 chr21:40591381 A/G cg17971929 chr21:40555470 PSMG1 -0.39 -5.82 -0.3 1.35e-8 Menarche (age at onset); LIHC cis rs2549003 1.000 rs9282761 chr5:131822224 T/C cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs3812831 0.695 rs3118895 chr13:114931742 G/A cg06611532 chr13:114900021 NA 0.43 7.91 0.39 3.71e-14 Schizophrenia; LIHC cis rs2404602 0.622 rs11632670 chr15:76974055 A/G cg23625390 chr15:77176239 SCAPER -0.55 -9.33 -0.45 1.41e-18 Blood metabolite levels; LIHC cis rs9325144 0.600 rs1825807 chr12:38737007 T/C cg26384229 chr12:38710491 ALG10B 0.56 7.82 0.39 6.52e-14 Morning vs. evening chronotype; LIHC cis rs5769765 0.908 rs2319464 chr22:50265777 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs9457247 0.935 rs2149093 chr6:167373045 T/C cg12798992 chr6:167411361 FGFR1OP -0.54 -8.38 -0.41 1.44e-15 Crohn's disease; LIHC cis rs8067354 0.645 rs56236317 chr17:57822125 C/T cg02344993 chr17:57696989 CLTC 0.7 11.89 0.54 1.66e-27 Hemoglobin concentration; LIHC cis rs10791097 0.694 rs4370948 chr11:130755700 A/C cg14779329 chr11:130786720 SNX19 0.43 6.52 0.33 2.6e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9503598 0.636 rs6596975 chr6:3465925 G/A cg00476032 chr6:3446245 SLC22A23 0.4 7.77 0.39 9.09e-14 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs7584330 0.554 rs76605518 chr2:238425992 G/A cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs12887734 0.546 rs12886637 chr14:104222892 A/G cg24130564 chr14:104152367 KLC1 0.43 7.05 0.36 9.65e-12 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs9790314 0.747 rs7650703 chr3:160851639 T/C cg03342759 chr3:160939853 NMD3 -0.68 -8.37 -0.41 1.54e-15 Morning vs. evening chronotype; LIHC cis rs3796352 1.000 rs2336541 chr3:52974630 G/C cg07884673 chr3:53033167 SFMBT1 0.88 6.5 0.33 2.77e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg11494091 chr17:61959527 GH2 0.44 8.03 0.4 1.61e-14 Prudent dietary pattern; LIHC cis rs17125944 0.686 rs3818453 chr14:53326454 C/A cg00686598 chr14:53173677 PSMC6 -0.75 -8.51 -0.42 5.49e-16 Alzheimer's disease (late onset); LIHC cis rs2153535 0.580 rs9378556 chr6:8514695 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs16958440 0.867 rs75287977 chr18:44686823 G/A cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs7824557 0.767 rs6985460 chr8:11171087 A/C cg21775007 chr8:11205619 TDH 0.45 6.57 0.33 1.89e-10 Retinal vascular caliber; LIHC cis rs6762 0.748 rs28677123 chr11:840604 C/G cg16425592 chr11:842748 TSPAN4;POLR2L -0.81 -9.72 -0.47 6.83e-20 Mean platelet volume; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg06873352 chr17:61820015 STRADA 0.52 7.56 0.38 3.63e-13 Height; LIHC cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg00684032 chr4:1343700 KIAA1530 -0.38 -6.29 -0.32 9.44e-10 Obesity-related traits; LIHC cis rs2066819 1.000 rs78121408 chr12:56684798 C/T cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg13395646 chr4:1353034 KIAA1530 -0.63 -8.99 -0.44 1.66e-17 Obesity-related traits; LIHC cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg02187348 chr16:89574699 SPG7 0.64 9.97 0.47 1e-20 Multiple myeloma (IgH translocation); LIHC cis rs911119 0.955 rs12625716 chr20:23606845 A/G cg16589663 chr20:23618590 CST3 -0.78 -8.24 -0.41 3.81e-15 Chronic kidney disease; LIHC cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg02353165 chr6:42928485 GNMT 0.94 15.14 0.63 5.24e-40 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs17384381 0.734 rs12129013 chr1:85891709 A/C cg16011679 chr1:85725395 C1orf52 0.46 6.01 0.31 4.79e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9549367 0.789 rs912012 chr13:113886152 G/A cg18105134 chr13:113819100 PROZ -0.67 -11.6 -0.53 1.83e-26 Platelet distribution width; LIHC cis rs735396 0.595 rs2258287 chr12:121454313 G/T cg02403541 chr12:121454288 C12orf43 0.73 14.04 0.6 1.1e-35 N-glycan levels; LIHC cis rs2629540 0.847 rs10901811 chr10:126417914 G/A cg20435097 chr10:126320824 FAM53B -0.45 -6.71 -0.34 7.85e-11 Cocaine dependence; LIHC trans rs61931739 0.500 rs11053278 chr12:34555955 T/C cg26384229 chr12:38710491 ALG10B 0.63 8.01 0.4 1.76e-14 Morning vs. evening chronotype; LIHC cis rs939574 0.512 rs2276638 chr2:220145286 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.59 7.08 0.36 8.04e-12 Platelet distribution width; LIHC cis rs7224685 0.569 rs12942513 chr17:4016721 C/A cg09597638 chr17:3907349 NA 0.54 6.45 0.33 3.83e-10 Type 2 diabetes; LIHC cis rs67460515 0.892 rs73026976 chr3:160964271 G/A cg03342759 chr3:160939853 NMD3 -0.67 -10.11 -0.48 3.36e-21 Parkinson's disease; LIHC cis rs12188164 0.543 rs7728027 chr5:459943 T/C cg07599136 chr5:415885 AHRR 0.39 6.75 0.34 6.32e-11 Cystic fibrosis severity; LIHC cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg05368731 chr17:41323189 NBR1 0.74 12.65 0.56 2.3e-30 Menopause (age at onset); LIHC cis rs9457247 0.637 rs9459846 chr6:167441023 T/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.73 -0.43 1.13e-16 Crohn's disease; LIHC cis rs7258465 0.931 rs76195 chr19:18629830 A/G cg10790698 chr19:18539756 SSBP4 -0.34 -7.16 -0.36 4.89e-12 Breast cancer; LIHC cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg02931644 chr1:25747376 RHCE 0.33 6.94 0.35 1.99e-11 Erythrocyte sedimentation rate; LIHC cis rs2991971 0.967 rs937291 chr1:45957039 G/T cg24296786 chr1:45957014 TESK2 0.58 9.24 0.45 2.63e-18 High light scatter reticulocyte count; LIHC trans rs1814175 0.791 rs9787917 chr11:49937281 C/T cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs2832191 0.791 rs28633762 chr21:30500070 C/T cg08807101 chr21:30365312 RNF160 -0.57 -8.9 -0.43 3.44e-17 Dental caries; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg20276947 chr17:80056775 FASN 0.49 6.04 0.31 4.13e-9 Hepatitis; LIHC cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.37 0.45 1e-18 Bipolar disorder; LIHC cis rs561341 1.000 rs111454793 chr17:30319267 T/C cg00745463 chr17:30367425 LRRC37B -0.77 -5.73 -0.3 2.16e-8 Hip circumference adjusted for BMI; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg19451033 chr5:141276143 LOC729080 0.41 6.2 0.32 1.66e-9 Hepatitis; LIHC cis rs5769765 0.542 rs738707 chr22:50250827 G/A cg09182678 chr22:50328711 NA 0.46 6.0 0.31 5.01e-9 Schizophrenia; LIHC cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg12016809 chr21:47604291 C21orf56 0.42 6.21 0.32 1.58e-9 Testicular germ cell tumor; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27347728 chr4:17578864 LAP3 0.47 6.04 0.31 4.08e-9 Lung function (FEV1/FVC); LIHC cis rs918629 0.679 rs12055287 chr5:95272428 G/C cg10483112 chr5:95245456 ELL2 -0.37 -6.24 -0.32 1.28e-9 IgG glycosylation; LIHC cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.1 0.51 1.19e-24 Platelet count; LIHC cis rs58785573 0.624 rs337605 chr4:38647753 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.43 6.13 0.31 2.39e-9 Lymphocyte percentage of white cells; LIHC cis rs67311347 1.000 rs6599102 chr3:40468406 G/A cg00656387 chr3:40428638 ENTPD3 0.41 6.91 0.35 2.32e-11 Renal cell carcinoma; LIHC cis rs17685 0.753 rs1637037 chr7:75692927 C/T cg04610667 chr7:75704037 NA -0.35 -6.25 -0.32 1.23e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9916302 0.851 rs677888 chr17:37461018 T/G cg00129232 chr17:37814104 STARD3 0.37 5.86 0.3 1.11e-8 Glomerular filtration rate (creatinine); LIHC cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.51 0.49 1.36e-22 Total body bone mineral density; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs67460515 0.892 rs7647374 chr3:160975576 T/A cg17135325 chr3:160939158 NMD3 0.55 7.84 0.39 5.59e-14 Parkinson's disease; LIHC cis rs2842992 0.789 rs4709376 chr6:160226337 A/G cg11366901 chr6:160182831 ACAT2 0.95 15.74 0.65 2.17e-42 Age-related macular degeneration (geographic atrophy); LIHC cis rs546131 0.642 rs11603640 chr11:34832907 G/T cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.62 -0.34 1.36e-10 Lung disease severity in cystic fibrosis; LIHC cis rs3796352 1.000 rs35737577 chr3:53002557 G/C cg07884673 chr3:53033167 SFMBT1 0.9 6.59 0.34 1.65e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg18279126 chr7:2041391 MAD1L1 0.36 6.02 0.31 4.6e-9 Bipolar disorder and schizophrenia; LIHC cis rs10256972 0.524 rs6945202 chr7:1116558 T/C cg04025307 chr7:1156635 C7orf50 0.39 5.95 0.31 6.75e-9 Longevity;Endometriosis; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg16405210 chr4:1374714 KIAA1530 -0.9 -14.5 -0.62 1.79e-37 Longevity; LIHC cis rs13161895 1.000 rs4235504 chr5:179453680 T/C cg06664874 chr5:179499304 RNF130 0.57 7.01 0.35 1.3e-11 LDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10373645 chr2:74007265 DUSP11 0.51 6.65 0.34 1.13e-10 Lung function (FEV1/FVC); LIHC cis rs9303401 0.659 rs62083410 chr17:56964386 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.34 0.58 5.91e-33 Cognitive test performance; LIHC cis rs933688 1.000 rs1035476 chr5:90745976 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.87 16.15 0.66 5.16e-44 Smoking behavior; LIHC cis rs13191362 1.000 rs67025553 chr6:163011552 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.62 5.78 0.3 1.69e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7238033 0.624 rs12455090 chr18:43313367 A/G cg20610511 chr18:43302872 SLC14A1 -0.38 -6.4 -0.33 4.99e-10 Bladder cancer; LIHC cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg27297192 chr10:134578999 INPP5A 0.51 7.78 0.39 8.43e-14 Migraine; LIHC cis rs4407350 0.870 rs4823329 chr22:44910117 T/C cg11695653 chr22:44894386 LDOC1L -0.36 -6.06 -0.31 3.69e-9 Intelligence (multi-trait analysis); LIHC cis rs1395 0.710 rs1992291 chr2:27504312 A/G cg22903471 chr2:27725779 GCKR -0.44 -6.59 -0.34 1.71e-10 Blood metabolite levels; LIHC cis rs6461049 0.800 rs3778977 chr7:2159746 C/T cg21782813 chr7:2030301 MAD1L1 0.36 6.23 0.32 1.37e-9 Schizophrenia; LIHC cis rs9921222 0.521 rs757460 chr16:367174 G/C cg12437481 chr16:420112 MRPL28 -0.59 -7.8 -0.39 7.69e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs9814567 0.806 rs9857242 chr3:134316378 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 9.36 0.45 1.1e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4907240 0.961 rs7580048 chr2:97304180 G/C cg26665480 chr2:98280029 ACTR1B -0.4 -5.96 -0.31 6.34e-9 Event-related brain oscillations; LIHC cis rs8114671 0.562 rs6120758 chr20:33492523 C/T cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.03e-19 Height; LIHC cis rs2304069 0.565 rs13183261 chr5:149421847 T/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.6 8.38 0.41 1.35e-15 HIV-1 control; LIHC cis rs2288073 0.801 rs2384008 chr2:24373150 A/G cg06627628 chr2:24431161 ITSN2 -0.52 -7.02 -0.36 1.17e-11 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs858239 0.665 rs858306 chr7:23242754 A/T cg18081818 chr7:23246105 NA -0.46 -7.07 -0.36 8.79e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs34779708 0.931 rs35136660 chr10:35385973 C/A cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00338116 chr13:43566313 EPSTI1 0.43 6.12 0.31 2.53e-9 Lung function (FEV1/FVC); LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg26338869 chr17:61819248 STRADA 0.57 8.19 0.41 5.15e-15 Prudent dietary pattern; LIHC cis rs12477438 1.000 rs1922624 chr2:99909958 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -8.52 -0.42 5.21e-16 Chronic sinus infection; LIHC cis rs1568889 0.838 rs3812738 chr11:28129982 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.11 0.61 5.99e-36 Bipolar disorder; LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs9467773 0.935 rs4573 chr6:26546808 A/G cg09904177 chr6:26538194 HMGN4 0.57 11.18 0.52 6.19e-25 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.501 rs6753063 chr2:99801469 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.66 0.65 4.89e-42 Chronic sinus infection; LIHC cis rs2404602 0.735 rs11632222 chr15:76712927 C/G cg23625390 chr15:77176239 SCAPER -0.47 -7.78 -0.39 8.76e-14 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14011500 chr6:126101974 NA -0.45 -6.58 -0.34 1.79e-10 Pancreatic cancer; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg24209194 chr3:40518798 ZNF619 0.63 9.66 0.46 1.13e-19 Renal cell carcinoma; LIHC cis rs1005277 0.638 rs1005278 chr10:38218748 G/A cg25427524 chr10:38739819 LOC399744 0.46 7.71 0.38 1.41e-13 Extrinsic epigenetic age acceleration; LIHC trans rs617791 0.508 rs10791837 chr11:65774596 C/T cg17712092 chr4:129076599 LARP1B -0.56 -6.76 -0.34 5.92e-11 Breast cancer; LIHC cis rs6546550 0.901 rs6741449 chr2:70156589 A/G cg02498382 chr2:70120550 SNRNP27 -0.43 -7.46 -0.37 6.98e-13 Prevalent atrial fibrillation; LIHC cis rs5753618 0.561 rs5753609 chr22:31819212 A/G cg02404636 chr22:31891804 SFI1 0.35 5.96 0.31 6.16e-9 Colorectal cancer; LIHC cis rs4908768 0.501 rs7530745 chr1:8557691 A/C cg20416874 chr1:8611966 RERE -0.66 -13.46 -0.59 2.02e-33 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg23749163 chr14:77563968 KIAA1737 -0.39 -6.13 -0.31 2.41e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1559088 1.000 rs8106453 chr19:33557412 C/T cg27124370 chr19:33622961 WDR88 0.47 7.09 0.36 7.77e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs12893668 0.645 rs35229468 chr14:104052057 C/T cg19000871 chr14:103996768 TRMT61A -0.4 -6.43 -0.33 4.36e-10 Reticulocyte count; LIHC cis rs7953249 0.807 rs2393791 chr12:121423956 A/G cg02403541 chr12:121454288 C12orf43 0.37 6.37 0.33 6.09e-10 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs35110281 0.720 rs162375 chr21:44927015 C/T cg21573476 chr21:45109991 RRP1B 0.56 10.41 0.49 3.26e-22 Mean corpuscular volume; LIHC trans rs1005277 0.505 rs10827836 chr10:38215441 A/G cg17830980 chr10:43048298 ZNF37B 0.46 8.85 0.43 4.95e-17 Extrinsic epigenetic age acceleration; LIHC cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg16434002 chr17:42200994 HDAC5 -0.52 -7.64 -0.38 2.25e-13 Total body bone mineral density; LIHC cis rs600806 0.813 rs6664236 chr1:109986672 C/A cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.92 -0.3 8.04e-9 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.602 rs2157050 chr6:26020431 C/T cg18357526 chr6:26021779 HIST1H4A 0.49 7.24 0.36 2.97e-12 Height; LIHC cis rs1816752 0.870 rs2033954 chr13:25010567 C/T cg22771759 chr13:24902376 NA 0.32 6.7 0.34 8.43e-11 Obesity-related traits; LIHC trans rs743793 0.818 rs137364 chr22:33576488 T/C cg20274824 chr1:36638199 MAP7D1 0.45 6.38 0.33 5.92e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs4713118 0.662 rs149947 chr6:27972433 A/T cg16479474 chr6:28041457 NA 0.45 6.78 0.34 5.41e-11 Parkinson's disease; LIHC cis rs57502260 0.749 rs67446678 chr11:68227466 C/T cg16797656 chr11:68205561 LRP5 0.58 7.84 0.39 5.68e-14 Total body bone mineral density (age 45-60); LIHC cis rs7116495 0.737 rs475959 chr11:71605332 A/G cg26138937 chr11:71823887 C11orf51 0.68 6.68 0.34 9.69e-11 Severe influenza A (H1N1) infection; LIHC cis rs10911363 0.549 rs12742245 chr1:183446922 T/A cg09173681 chr1:183549694 NCF2 0.56 9.74 0.47 6.08e-20 Systemic lupus erythematosus; LIHC cis rs765787 0.530 rs2413784 chr15:45530516 A/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs2228479 0.850 rs17233664 chr16:89810628 C/T cg06558623 chr16:89946397 TCF25 0.87 11.95 0.54 9.72e-28 Skin colour saturation; LIHC cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg18357526 chr6:26021779 HIST1H4A 0.58 8.04 0.4 1.49e-14 Blood metabolite levels; LIHC cis rs10504073 0.647 rs10808745 chr8:49989037 G/A cg00325661 chr8:49890786 NA 0.33 7.64 0.38 2.15e-13 Blood metabolite ratios; LIHC cis rs7027203 0.964 rs6479512 chr9:96556985 G/A cg14598338 chr9:96623480 NA 0.32 5.81 0.3 1.44e-8 DNA methylation (variation); LIHC cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg12463550 chr7:65579703 CRCP -0.66 -6.83 -0.35 3.91e-11 Diabetic kidney disease; LIHC cis rs898097 0.812 rs7406011 chr17:80829980 C/T cg15664640 chr17:80829946 TBCD -0.77 -12.77 -0.57 8.33e-31 Breast cancer; LIHC cis rs9427116 0.740 rs11264230 chr1:154608418 G/T cg17218026 chr1:154582156 ADAR 0.34 6.51 0.33 2.65e-10 Blood protein levels; LIHC cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg23248424 chr5:179741104 GFPT2 -0.42 -6.37 -0.33 6e-10 Height; LIHC cis rs35110281 0.776 rs229357 chr21:44982717 T/C cg04455712 chr21:45112962 RRP1B 0.47 7.86 0.39 5.02e-14 Mean corpuscular volume; LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg07677032 chr17:61819896 STRADA 0.43 6.41 0.33 4.8e-10 Prudent dietary pattern; LIHC cis rs10751667 1.000 rs7927156 chr11:970607 A/G cg10932868 chr11:921992 NA 0.32 5.74 0.3 2.06e-8 Alzheimer's disease (late onset); LIHC cis rs7727544 0.684 rs2631363 chr5:131707095 A/G cg07395648 chr5:131743802 NA 0.31 6.44 0.33 3.95e-10 Blood metabolite levels; LIHC cis rs2404602 0.692 rs8037005 chr15:76951109 C/T cg03037974 chr15:76606532 NA 0.75 14.48 0.62 2.07e-37 Blood metabolite levels; LIHC cis rs9921222 0.565 rs10903014 chr16:377623 A/G cg12437481 chr16:420112 MRPL28 -0.49 -7.63 -0.38 2.42e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs2120019 0.505 rs77456790 chr15:75330095 G/T cg17294928 chr15:75287854 SCAMP5 -0.53 -6.45 -0.33 3.86e-10 Blood trace element (Zn levels); LIHC cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs2629540 0.889 rs7476729 chr10:126428174 C/G cg08799069 chr10:126477246 METTL10 -0.5 -7.78 -0.39 8.91e-14 Cocaine dependence; LIHC cis rs2834188 0.889 rs8134026 chr21:34671098 T/A cg04842828 chr21:34696676 IFNAR1 0.47 6.23 0.32 1.39e-9 Narcolepsy; LIHC cis rs1816752 0.633 rs8002387 chr13:24990444 A/G cg22771759 chr13:24902376 NA 0.31 6.06 0.31 3.57e-9 Obesity-related traits; LIHC cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg06481639 chr22:41940642 POLR3H -0.7 -6.95 -0.35 1.9e-11 Vitiligo; LIHC cis rs9790314 0.663 rs7630674 chr3:160813597 G/A cg03342759 chr3:160939853 NMD3 -0.73 -10.1 -0.48 3.77e-21 Morning vs. evening chronotype; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23054166 chr20:5986708 CRLS1 -0.46 -6.24 -0.32 1.32e-9 Systolic blood pressure; LIHC cis rs67311347 0.956 rs12633446 chr3:40505661 G/A cg00656387 chr3:40428638 ENTPD3 -0.45 -7.6 -0.38 2.92e-13 Renal cell carcinoma; LIHC trans rs59574136 1 rs59574136 chr7:2036460 T/C cg04565464 chr8:145669602 NFKBIL2 0.41 6.86 0.35 3.14e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs36051895 0.626 rs10283564 chr9:5075628 C/G cg02405213 chr9:5042618 JAK2 -0.67 -11.3 -0.52 2.21e-25 Pediatric autoimmune diseases; LIHC cis rs911119 1.000 rs3787498 chr20:23616781 C/T cg16589663 chr20:23618590 CST3 0.75 7.66 0.38 1.98e-13 Chronic kidney disease; LIHC cis rs2857078 0.654 rs9896789 chr17:42314567 C/T cg13607699 chr17:42295918 UBTF 0.75 15.31 0.64 1.16e-40 Red cell distribution width;Reticulocyte count; LIHC cis rs2857078 0.720 rs9901595 chr17:42305699 G/A cg08499158 chr17:42289980 UBTF -0.49 -7.94 -0.39 2.91e-14 Red cell distribution width;Reticulocyte count; LIHC trans rs1945213 0.694 rs7122627 chr11:55862565 A/G cg15704280 chr7:45808275 SEPT13 0.59 7.68 0.38 1.71e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6598955 0.543 rs60433268 chr1:26548055 A/C cg04990556 chr1:26633338 UBXN11 0.76 11.03 0.51 2.02e-24 Obesity-related traits; LIHC cis rs1568889 0.838 rs7131053 chr11:28143312 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.18 0.61 3.24e-36 Bipolar disorder; LIHC cis rs7945705 0.935 rs11042103 chr11:8888700 C/T cg12365402 chr11:9010492 NRIP3 0.29 7.46 0.37 7.28e-13 Hemoglobin concentration; LIHC trans rs17685 0.753 rs1806885 chr7:75785612 T/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7772486 0.686 rs9403746 chr6:146103768 C/A cg05347473 chr6:146136440 FBXO30 -0.36 -5.77 -0.3 1.81e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs12477438 0.798 rs9808541 chr2:99642179 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.84 -0.65 9.44e-43 Chronic sinus infection; LIHC trans rs208520 1.000 rs12209225 chr6:66996443 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.67 7.2 0.36 3.84e-12 Exhaled nitric oxide output; LIHC cis rs208520 0.690 rs207082 chr6:66773796 G/A cg07460842 chr6:66804631 NA -0.8 -9.28 -0.45 1.93e-18 Exhaled nitric oxide output; LIHC cis rs11758351 1.000 rs16891405 chr6:26204506 A/G cg06951627 chr6:26196580 NA 0.55 6.19 0.32 1.71e-9 Gout;Renal underexcretion gout; LIHC cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg06481639 chr22:41940642 POLR3H 0.72 7.09 0.36 7.94e-12 Vitiligo; LIHC cis rs7772486 0.875 rs2474353 chr6:146323883 G/A cg23711669 chr6:146136114 FBXO30 0.67 11.67 0.53 1.05e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 1.000 rs4660895 chr1:46329739 C/T cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1461503 0.903 rs7124683 chr11:122834036 A/G cg25161029 chr11:122845972 NA -0.43 -7.38 -0.37 1.21e-12 Menarche (age at onset); LIHC cis rs7927771 1.000 rs12787330 chr11:47812311 C/T cg20307385 chr11:47447363 PSMC3 -0.44 -5.82 -0.3 1.36e-8 Subjective well-being; LIHC cis rs10751667 1.000 rs7395632 chr11:958789 C/T cg06064525 chr11:970664 AP2A2 0.48 11.82 0.54 2.9e-27 Alzheimer's disease (late onset); LIHC cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg02951883 chr7:2050386 MAD1L1 -0.52 -7.77 -0.39 9.16e-14 Bipolar disorder and schizophrenia; LIHC cis rs965469 0.779 rs2236088 chr20:3256342 T/C cg25506879 chr20:3388711 C20orf194 -0.54 -6.68 -0.34 9.87e-11 IFN-related cytopenia; LIHC cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg10295955 chr4:187884368 NA -0.95 -20.89 -0.75 5.02e-63 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.528 rs801213 chr7:66014918 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.35 -7.0 -0.35 1.34e-11 Aortic root size; LIHC cis rs4690686 0.769 rs7660827 chr4:177274542 T/C cg17059388 chr4:177262070 NA 0.36 6.69 0.34 9.24e-11 Essential tremor; LIHC cis rs7165170 0.549 rs6496689 chr15:91096915 C/T cg26821196 chr15:91095069 CRTC3 -0.35 -6.2 -0.32 1.58e-9 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1035144 0.546 rs2215981 chr14:81444967 G/A cg06600135 chr14:81408086 NA -0.44 -7.61 -0.38 2.64e-13 Male sexual orientation; LIHC cis rs763121 0.853 rs8142098 chr22:39058757 T/G cg14440974 chr22:39074834 NA -0.43 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC trans rs11098499 0.863 rs1480939 chr4:120456927 T/C cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs7149337 0.805 rs2999354 chr14:51607179 C/G cg23942311 chr14:51606299 NA 0.35 7.33 0.37 1.7e-12 Cancer; LIHC cis rs7572733 0.515 rs12619300 chr2:198786490 A/C cg10820045 chr2:198174542 NA -0.47 -7.19 -0.36 4.07e-12 Dermatomyositis; LIHC cis rs600806 0.745 rs4246517 chr1:110007636 G/C cg10127483 chr1:110009974 SYPL2 0.47 5.98 0.31 5.6e-9 Intelligence (multi-trait analysis); LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg11965913 chr1:205819406 PM20D1 0.63 9.24 0.45 2.71e-18 Menarche (age at onset); LIHC cis rs1451375 0.756 rs11761683 chr7:50542879 C/T cg14593290 chr7:50529359 DDC -0.48 -7.97 -0.4 2.37e-14 Malaria; LIHC trans rs2797160 1.000 rs2211419 chr6:125995533 C/T cg05039488 chr6:79577232 IRAK1BP1 0.47 6.88 0.35 2.84e-11 Endometrial cancer; LIHC cis rs1144333 0.655 rs1146602 chr1:76239309 A/G cg03433033 chr1:76189801 ACADM -0.56 -7.73 -0.39 1.19e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs34172651 0.537 rs8049014 chr16:24698903 A/G cg04756594 chr16:24857601 SLC5A11 0.37 5.92 0.3 7.96e-9 Intelligence (multi-trait analysis); LIHC cis rs3749237 0.595 rs7637999 chr3:49535115 C/T cg02487422 chr3:49467188 NICN1 0.41 6.32 0.32 8.18e-10 Resting heart rate; LIHC cis rs6570726 0.846 rs6914304 chr6:145921017 T/C cg23711669 chr6:146136114 FBXO30 0.61 10.5 0.49 1.53e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs8078723 0.714 rs12940405 chr17:38143768 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.29 0.52 2.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs3617 0.503 rs9866243 chr3:52915219 C/T cg11645453 chr3:52864694 ITIH4 -0.23 -6.32 -0.32 8.15e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs10540 0.730 rs61876338 chr11:493730 A/G cg03352830 chr11:487213 PTDSS2 0.82 6.88 0.35 2.87e-11 Body mass index; LIHC cis rs2404602 0.647 rs3812908 chr15:77176158 C/T cg23625390 chr15:77176239 SCAPER 0.58 9.99 0.48 8.77e-21 Blood metabolite levels; LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg14893161 chr1:205819251 PM20D1 0.81 12.07 0.55 3.47e-28 Menarche (age at onset); LIHC cis rs3796352 0.568 rs11713376 chr3:52958927 A/G cg04865290 chr3:52927548 TMEM110 -0.49 -6.19 -0.32 1.68e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs11779988 0.528 rs208029 chr8:17840987 A/C cg01800426 chr8:17659068 MTUS1 -0.41 -5.89 -0.3 9.37e-9 Breast cancer; LIHC cis rs6088590 1.000 rs3787222 chr20:33333040 T/A cg24642439 chr20:33292090 TP53INP2 0.79 11.42 0.53 8.51e-26 Coronary artery disease; LIHC cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.49 0.49 1.63e-22 Colorectal cancer; LIHC cis rs10751667 0.621 rs4075990 chr11:976614 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg02034447 chr16:89574710 SPG7 0.48 7.31 0.37 1.93e-12 Multiple myeloma (IgH translocation); LIHC cis rs6543140 0.572 rs17027173 chr2:103057043 G/A cg09003973 chr2:102972529 NA 0.82 8.41 0.41 1.1e-15 Blood protein levels; LIHC cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs1577917 0.958 rs72907388 chr6:86440207 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.81 -0.5 1.22e-23 Response to antipsychotic treatment; LIHC cis rs17666538 0.585 rs4448252 chr8:615597 A/G cg13264159 chr8:625131 ERICH1 -0.62 -6.28 -0.32 1.06e-9 IgG glycosylation; LIHC cis rs1144333 0.655 rs968018 chr1:76395662 G/A cg10523679 chr1:76189770 ACADM 0.47 6.36 0.33 6.47e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs1005277 0.579 rs2983343 chr10:38383332 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs11588062 1.000 rs11588062 chr1:46779764 C/T cg06787764 chr1:46668870 C1orf190;POMGNT1 0.61 9.65 0.46 1.2e-19 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9914988 0.832 rs11650788 chr17:27174523 T/A cg20469991 chr17:27169893 C17orf63 -0.54 -6.35 -0.32 6.69e-10 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg10360139 chr7:1886902 MAD1L1 -0.41 -6.3 -0.32 9.03e-10 Bipolar disorder and schizophrenia; LIHC cis rs80282103 0.764 rs10047382 chr10:1102868 T/C cg18964960 chr10:1102726 WDR37 0.7 6.6 0.34 1.55e-10 Glomerular filtration rate (creatinine); LIHC cis rs2334880 0.678 rs6499520 chr16:71458100 C/T cg06353428 chr16:71660113 MARVELD3 -0.81 -8.01 -0.4 1.87e-14 Malaria; LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.75 0.39 1.07e-13 Prudent dietary pattern; LIHC cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg24101359 chr6:42928495 GNMT 0.48 6.36 0.33 6.61e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs13191362 0.935 rs66635391 chr6:162964577 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.65 5.72 0.3 2.35e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7937682 0.663 rs35581942 chr11:111756286 C/T cg09085632 chr11:111637200 PPP2R1B 0.93 13.38 0.59 3.93e-33 Primary sclerosing cholangitis; LIHC cis rs11628318 0.614 rs8013886 chr14:103117389 A/G cg01864069 chr14:103024347 NA 0.35 5.8 0.3 1.48e-8 Platelet count; LIHC cis rs16828019 0.852 rs12729448 chr1:41509834 G/A cg03962019 chr1:41807865 NA 0.49 7.03 0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.866 rs7677068 chr4:120291704 C/T cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg24846343 chr22:24311635 DDTL 0.68 13.1 0.58 4.79e-32 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6088590 0.735 rs6088618 chr20:33409350 G/A cg06115741 chr20:33292138 TP53INP2 0.42 5.95 0.31 6.77e-9 Coronary artery disease; LIHC cis rs7216064 0.953 rs1966410 chr17:65837215 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.74 -0.47 6.22e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs5769765 0.908 rs138880 chr22:50218611 A/C cg02269571 chr22:50332266 NA -0.69 -9.28 -0.45 2.03e-18 Schizophrenia; LIHC cis rs7589728 0.563 rs79892776 chr2:88470593 G/A cg07952391 chr2:88470173 THNSL2 0.81 7.75 0.39 1.06e-13 Plasma clusterin levels; LIHC cis rs826838 0.868 rs12322306 chr12:39130021 A/G cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC trans rs950169 0.614 rs12903883 chr15:84680553 A/G cg24036039 chr1:3397125 ARHGEF16 0.39 6.43 0.33 4.3e-10 Schizophrenia; LIHC cis rs9814567 1.000 rs4309773 chr3:134277301 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs651907 0.535 rs4342086 chr3:101503765 G/A cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.86 -0.3 1.1e-8 Colorectal cancer; LIHC cis rs4820539 0.708 rs5751591 chr22:23489042 G/A cg21100191 chr22:23484243 RTDR1 0.73 8.22 0.41 4.24e-15 Bone mineral density; LIHC cis rs17376456 0.569 rs11135397 chr5:93214975 G/T cg25358565 chr5:93447407 FAM172A 0.77 7.68 0.38 1.73e-13 Diabetic retinopathy; LIHC cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs3806843 1.000 rs4151682 chr5:140201264 C/T cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 8.44 0.42 9.2e-16 Platelet count; LIHC cis rs9393692 0.905 rs34916901 chr6:26286149 G/T cg13736514 chr6:26305472 NA -0.38 -6.4 -0.33 5.04e-10 Educational attainment; LIHC cis rs1949733 1.000 rs3103072 chr4:8508431 C/T cg11789530 chr4:8429930 ACOX3 -0.77 -11.42 -0.53 8.61e-26 Response to antineoplastic agents; LIHC cis rs959260 1.000 rs7211915 chr17:73379872 A/G cg20590849 chr17:73267439 MIF4GD -0.53 -5.76 -0.3 1.85e-8 Systemic lupus erythematosus; LIHC cis rs6748734 0.948 rs9973366 chr2:241838151 T/C cg20140201 chr2:241835670 C2orf54 -0.53 -8.22 -0.41 4.32e-15 Urinary metabolites; LIHC trans rs11098499 0.865 rs28753180 chr4:120405367 A/T cg25214090 chr10:38739885 LOC399744 0.58 9.5 0.46 3.69e-19 Corneal astigmatism; LIHC cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg00684032 chr4:1343700 KIAA1530 -0.37 -6.12 -0.31 2.58e-9 Obesity-related traits; LIHC cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg18357526 chr6:26021779 HIST1H4A 0.61 8.58 0.42 3.44e-16 Blood metabolite levels; LIHC cis rs7213347 0.707 rs4790323 chr17:2181658 A/G cg15816464 chr17:2026533 SMG6 0.49 9.47 0.46 4.81e-19 Total body bone mineral density; LIHC cis rs9814567 0.806 rs4245904 chr3:134321808 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7582180 0.663 rs2309800 chr2:100992086 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.17 0.4 6e-15 Intelligence (multi-trait analysis); LIHC cis rs7086627 0.515 rs11202963 chr10:82210392 A/G cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs6942756 0.806 rs6967464 chr7:128909727 T/C cg02491457 chr7:128862824 NA 0.61 9.62 0.46 1.5700000000000001e-19 White matter hyperintensity burden; LIHC cis rs10464366 0.571 rs4723825 chr7:39157627 G/C cg18850127 chr7:39170497 POU6F2 0.46 8.09 0.4 1.04e-14 IgG glycosylation; LIHC cis rs7829975 0.688 rs7817376 chr8:8380530 C/T cg14343924 chr8:8086146 FLJ10661 -0.43 -5.93 -0.31 7.31e-9 Mood instability; LIHC cis rs72781680 1.000 rs72788280 chr2:24095907 A/G cg08917208 chr2:24149416 ATAD2B 0.86 8.16 0.4 6.31e-15 Lymphocyte counts; LIHC cis rs9733 0.596 rs56058687 chr1:150635066 C/T cg13175981 chr1:150552382 MCL1 -0.44 -6.07 -0.31 3.4e-9 Tonsillectomy; LIHC cis rs10752881 0.935 rs10911235 chr1:183053746 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Colorectal cancer; LIHC cis rs6882046 0.513 rs454214 chr5:88003403 A/G cg22951263 chr5:87985283 NA 0.41 7.2 0.36 3.76e-12 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs4819852 0.958 rs2238787 chr22:19976406 G/A cg07821417 chr22:19972146 ARVCF 0.46 6.61 0.34 1.48e-10 Pulse pressure; LIHC cis rs2370759 1.000 rs2225152 chr10:32574759 T/C cg05361325 chr10:32636312 EPC1 -0.52 -6.41 -0.33 4.77e-10 Sexual dysfunction (female); LIHC cis rs595982 0.559 rs17272680 chr19:49364511 A/G cg21252483 chr19:49399788 TULP2 0.84 9.81 0.47 3.38e-20 Red cell distribution width; LIHC cis rs9682041 0.935 rs11923053 chr3:170095281 T/C cg11886554 chr3:170076028 SKIL 0.72 6.21 0.32 1.58e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg10450322 chr1:51434373 CDKN2C 0.41 6.07 0.31 3.48e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs2073499 0.872 rs2282751 chr3:50291785 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.85 -13.45 -0.59 2.21e-33 Schizophrenia; LIHC cis rs2737618 0.651 rs2816975 chr1:200081159 A/G cg21825944 chr1:200113062 NR5A2 -0.45 -8.13 -0.4 8.1e-15 Uric acid levels; LIHC cis rs7833986 0.501 rs2667981 chr8:56894303 T/A cg23139584 chr8:56987506 RPS20;SNORD54 0.87 8.76 0.43 9.08e-17 Height; LIHC cis rs58235267 0.553 rs11890276 chr2:63366191 C/T cg17519650 chr2:63277830 OTX1 0.63 9.8 0.47 3.69e-20 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs9790314 0.613 rs13086250 chr3:160631965 G/A cg03342759 chr3:160939853 NMD3 0.56 7.38 0.37 1.25e-12 Morning vs. evening chronotype; LIHC cis rs2404602 0.647 rs12898810 chr15:76904738 T/C cg03037974 chr15:76606532 NA -0.6 -9.87 -0.47 2.28e-20 Blood metabolite levels; LIHC cis rs826838 0.967 rs7965656 chr12:38807244 G/A cg26384229 chr12:38710491 ALG10B 1.0 12.48 0.56 1.05e-29 Heart rate; LIHC cis rs798766 1.000 rs3752749 chr4:1737262 T/C cg21231739 chr4:1642635 FAM53A -0.38 -6.0 -0.31 4.9e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs2073300 1.000 rs12625160 chr20:23442008 T/C cg16736954 chr20:23401023 NAPB 0.53 5.91 0.3 8.15e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs769267 0.930 rs4808965 chr19:19631655 A/G cg03709012 chr19:19516395 GATAD2A 0.99 16.26 0.66 1.84e-44 Tonsillectomy; LIHC cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg13393036 chr8:95962371 TP53INP1 -0.38 -8.66 -0.42 1.87e-16 Type 2 diabetes; LIHC cis rs9457247 1.000 rs408080 chr6:167392522 T/C cg23791538 chr6:167370224 RNASET2 -0.59 -9.37 -0.45 1.02e-18 Crohn's disease; LIHC trans rs1034394 0.775 rs5999350 chr22:34818544 A/G cg02641517 chr3:54169983 CACNA2D3 -0.24 -6.1 -0.31 2.93e-9 Major depressive disorder; LIHC trans rs654384 0.866 rs13224870 chr7:4172006 C/T cg26675336 chr15:86133334 AKAP13 0.29 6.24 0.32 1.29e-9 Positive affect; LIHC cis rs67460515 0.531 rs13060601 chr3:160823159 G/A cg03342759 chr3:160939853 NMD3 -0.61 -8.89 -0.43 3.57e-17 Parkinson's disease; LIHC cis rs700651 0.789 rs1147169 chr2:198901395 C/T cg10820045 chr2:198174542 NA -0.44 -6.36 -0.33 6.48e-10 Intracranial aneurysm; LIHC cis rs2273156 1.000 rs12050390 chr14:35461079 A/C cg16230307 chr14:35515116 FAM177A1 -0.41 -6.04 -0.31 3.96e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs9457247 0.902 rs366938 chr6:167403538 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 10.02 0.48 6.67e-21 Crohn's disease; LIHC cis rs67311347 0.955 rs1129200 chr3:40532257 T/C cg24209194 chr3:40518798 ZNF619 0.56 7.97 0.4 2.33e-14 Renal cell carcinoma; LIHC cis rs13108904 0.901 rs66987549 chr4:1272617 C/T cg26570765 chr4:1273065 NA 0.3 5.75 0.3 2.01e-8 Obesity-related traits; LIHC cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg12311346 chr5:56204834 C5orf35 -0.64 -8.35 -0.41 1.71e-15 Initial pursuit acceleration; LIHC cis rs9916302 0.904 rs11654018 chr17:37703740 C/T cg07936489 chr17:37558343 FBXL20 0.84 13.56 0.59 7.95e-34 Glomerular filtration rate (creatinine); LIHC cis rs924607 1.000 rs12523022 chr5:598643 C/T cg04476341 chr5:669733 TPPP -0.41 -9.14 -0.44 5.49e-18 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs11105298 0.891 rs4842661 chr12:89930399 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.49 -0.38 6.04e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs8064299 0.597 rs4789098 chr17:72781292 C/G cg25054828 chr17:72772726 NAT9;TMEM104 0.71 12.59 0.56 3.89e-30 Monocyte count; LIHC cis rs17376456 0.778 rs72786662 chr5:93137630 C/T cg25358565 chr5:93447407 FAM172A 1.06 9.35 0.45 1.21e-18 Diabetic retinopathy; LIHC cis rs8062405 0.755 rs7186573 chr16:28587389 T/C cg00204512 chr16:28754710 NA 0.41 7.22 0.36 3.42e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.26e-9 Menopause (age at onset); LIHC cis rs4319547 0.508 rs10846826 chr12:122894987 C/T cg23029597 chr12:123009494 RSRC2 -0.52 -7.34 -0.37 1.54e-12 Body mass index; LIHC cis rs55894533 0.597 rs2645408 chr8:11746358 A/G cg21281001 chr8:11725306 CTSB 0.59 8.91 0.43 3.01e-17 Leprosy; LIHC cis rs1256061 0.603 rs1269056 chr14:64743890 T/C cg23250157 chr14:64679961 SYNE2 0.4 5.92 0.3 8.02e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs897984 0.806 rs8052245 chr16:30916430 C/G cg02466173 chr16:30829666 NA 0.44 7.14 0.36 5.75e-12 Dementia with Lewy bodies; LIHC cis rs10464366 0.544 rs953874 chr7:39147916 G/A cg15212455 chr7:39170539 POU6F2 0.46 8.23 0.41 3.99e-15 IgG glycosylation; LIHC cis rs796364 0.806 rs74938253 chr2:201008386 T/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.54 -6.15 -0.32 2.16e-9 Schizophrenia; LIHC cis rs2777491 0.957 rs8026197 chr15:41711447 C/T cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.29 -0.45 1.85e-18 Ulcerative colitis; LIHC cis rs11098499 0.754 rs2036856 chr4:120249288 G/A cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.01e-25 Corneal astigmatism; LIHC cis rs112158604 1 rs112158604 chr1:150696792 TCTTCTGCAG/T cg17724175 chr1:150552817 MCL1 -0.37 -7.69 -0.38 1.59e-13 Lymphocyte counts; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01078248 chr7:123197661 NDUFA5 0.45 7.04 0.36 1.08e-11 Cognitive function; LIHC cis rs2637266 0.935 rs2579720 chr10:78399918 T/C cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg12311346 chr5:56204834 C5orf35 -0.65 -8.4 -0.41 1.21e-15 Initial pursuit acceleration; LIHC cis rs1387259 0.759 rs7960122 chr12:48777000 C/T cg21466736 chr12:48725269 NA 0.6 8.79 0.43 7.59e-17 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs4474465 0.790 rs4945292 chr11:78254424 T/A cg27205649 chr11:78285834 NARS2 0.4 6.29 0.32 9.51e-10 Alzheimer's disease (survival time); LIHC cis rs11583043 1.000 rs35445887 chr1:101523639 C/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.08 0.31 3.24e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs8017423 0.967 rs8009493 chr14:90690083 G/C cg14092571 chr14:90743983 NA -0.38 -5.94 -0.31 7.18e-9 Mortality in heart failure; LIHC cis rs3806843 0.706 rs1089305 chr5:140066306 T/C cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs600806 0.821 rs417270 chr1:109849144 T/C cg16275483 chr1:110013120 SYPL2 -0.51 -6.22 -0.32 1.47e-9 Intelligence (multi-trait analysis); LIHC cis rs7959452 0.535 rs11177577 chr12:69671791 C/T cg14784868 chr12:69753453 YEATS4 0.87 16.52 0.67 1.74e-45 Blood protein levels; LIHC cis rs4474465 0.790 rs6592784 chr11:78234790 C/T cg02023728 chr11:77925099 USP35 -0.35 -6.29 -0.32 9.8e-10 Alzheimer's disease (survival time); LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg13409248 chr3:40428643 ENTPD3 0.49 8.24 0.41 3.61e-15 Renal cell carcinoma; LIHC cis rs78456975 1.000 rs72776298 chr2:1570163 C/G cg01028140 chr2:1542097 TPO -0.49 -5.95 -0.31 6.8e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs7249142 0.549 rs2238667 chr19:19282523 G/A cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.35 -5.97 -0.31 5.84e-9 IgG glycosylation; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.55 -7.89 -0.39 4.02e-14 Lymphocyte counts; LIHC cis rs10540 1.000 rs35255804 chr11:492617 G/A cg03576123 chr11:487126 PTDSS2 -1.16 -8.65 -0.42 2.07e-16 Body mass index; LIHC cis rs11711311 1.000 rs9811353 chr3:113483979 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.94 -0.35 2e-11 IgG glycosylation; LIHC cis rs3008870 0.709 rs62883160 chr1:67392889 G/A cg02640540 chr1:67518911 SLC35D1 0.41 6.39 0.33 5.56e-10 Lymphocyte percentage of white cells; LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg13409248 chr3:40428643 ENTPD3 0.48 8.18 0.4 5.67e-15 Renal cell carcinoma; LIHC cis rs2108622 0.683 rs56228205 chr19:15981973 A/C cg13772218 chr19:15982569 NA 0.37 7.83 0.39 6.17e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs35883536 1.000 rs12239531 chr1:101085661 A/G cg14515779 chr1:101123966 NA -0.66 -12.4 -0.56 2.04e-29 Monocyte count; LIHC cis rs67311347 0.713 rs4974018 chr3:40307419 G/A cg13409248 chr3:40428643 ENTPD3 0.4 6.4 0.33 5.22e-10 Renal cell carcinoma; LIHC cis rs35110281 0.774 rs141521 chr21:44963686 G/A cg01579765 chr21:45077557 HSF2BP -0.32 -5.96 -0.31 6.39e-9 Mean corpuscular volume; LIHC cis rs9611519 0.929 rs11090039 chr22:41496800 G/A cg03806693 chr22:41940476 POLR3H -0.66 -6.93 -0.35 2.1e-11 Neuroticism; LIHC cis rs5769765 0.773 rs7290751 chr22:50318312 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.41 -0.45 7.59e-19 Schizophrenia; LIHC trans rs7656342 0.808 rs10003216 chr4:9766749 A/G cg05300132 chr14:69676275 EXD2 0.39 6.21 0.32 1.54e-9 Gut microbiota (bacterial taxa); LIHC cis rs4268898 1.000 rs1203 chr2:24443330 A/G cg06627628 chr2:24431161 ITSN2 0.51 7.25 0.37 2.72e-12 Asthma; LIHC cis rs3106136 0.934 rs35995707 chr4:95167150 C/G cg11021082 chr4:95130006 SMARCAD1 -0.45 -8.14 -0.4 7.63e-15 Capecitabine sensitivity; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg20295408 chr7:1910781 MAD1L1 -0.41 -5.91 -0.3 8.17e-9 Bipolar disorder and schizophrenia; LIHC cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs11864453 0.928 rs3213420 chr16:72042433 C/T cg01557791 chr16:72042693 DHODH -0.71 -11.51 -0.53 3.92e-26 Fibrinogen levels; LIHC cis rs7503168 1.000 rs16971217 chr17:33944055 C/G cg20932281 chr17:33905541 PEX12 0.55 7.15 0.36 5.39e-12 Plateletcrit; LIHC cis rs7945718 0.935 rs11022501 chr11:12809314 T/C cg25843174 chr11:12811716 TEAD1 0.28 6.62 0.34 1.4e-10 Educational attainment (years of education); LIHC cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg19774624 chr17:42201019 HDAC5 0.84 12.98 0.57 1.29e-31 Total body bone mineral density; LIHC cis rs35306767 0.903 rs34847097 chr10:902252 A/T cg20503657 chr10:835505 NA 1.07 12.08 0.55 3.31e-28 Eosinophil percentage of granulocytes; LIHC cis rs13096760 1 rs13096760 chr3:49476806 T/C cg02487422 chr3:49467188 NICN1 0.42 6.55 0.33 2.16e-10 Intelligence (multi-trait analysis); LIHC cis rs941873 0.803 rs5015119 chr10:81101609 G/C cg09469691 chr10:81107165 PPIF 0.68 10.46 0.49 2.17e-22 Height; LIHC cis rs11888559 0.655 rs4673243 chr2:204019844 G/A cg24605529 chr2:203879461 NBEAL1 0.77 5.82 0.3 1.34e-8 Height; LIHC cis rs74405815 0.510 rs6780441 chr3:126447838 A/G cg16285380 chr3:126373980 NA -0.66 -7.89 -0.39 4e-14 Response to paliperidone in schizophrenia (positive Marder score); LIHC cis rs11628318 0.588 rs12185065 chr14:103074636 A/C cg01864069 chr14:103024347 NA 0.35 5.95 0.31 6.68e-9 Platelet count; LIHC cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg00149659 chr3:10157352 C3orf10 0.68 7.12 0.36 6.57e-12 Alzheimer's disease; LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs4759375 1.000 rs12317452 chr12:123788246 C/T cg00376283 chr12:123451042 ABCB9 -0.5 -6.4 -0.33 5.02e-10 HDL cholesterol; LIHC cis rs4423214 1.000 rs11233746 chr11:71171440 A/G cg24826892 chr11:71159390 DHCR7 0.47 6.16 0.32 2.06e-9 Vitamin D levels; LIHC cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg08280861 chr8:58055591 NA 0.54 5.86 0.3 1.06e-8 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs7520050 0.966 rs1768803 chr1:46546208 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.79 0.3 1.56e-8 Red blood cell count;Reticulocyte count; LIHC cis rs17401966 0.537 rs3748575 chr1:10342352 C/T cg19773385 chr1:10388646 KIF1B -0.33 -5.98 -0.31 5.57e-9 Hepatocellular carcinoma; LIHC cis rs1580019 0.587 rs6968990 chr7:32552159 C/T cg14728415 chr7:32535168 LSM5;AVL9 -0.45 -6.44 -0.33 4.04e-10 Cognitive ability; LIHC cis rs11800820 0.555 rs6661155 chr1:246628943 C/G cg16700716 chr1:246684329 NA -0.41 -7.16 -0.36 4.97e-12 Obesity-related traits; LIHC cis rs9916302 0.904 rs9944411 chr17:37483599 T/C cg07936489 chr17:37558343 FBXL20 0.81 13.01 0.58 9.99e-32 Glomerular filtration rate (creatinine); LIHC cis rs4727027 0.704 rs12704071 chr7:148904795 C/T cg23583168 chr7:148888333 NA -0.75 -11.63 -0.53 1.38e-26 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs1215050 0.765 rs687795 chr4:98754912 C/G cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs826838 0.967 rs2069211 chr12:39128892 C/T cg26384229 chr12:38710491 ALG10B -0.62 -9.06 -0.44 9.91e-18 Heart rate; LIHC cis rs801193 0.967 rs1110414 chr7:66205582 A/G cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.5e-9 Aortic root size; LIHC cis rs6089584 0.893 rs6089306 chr20:60574868 G/A cg13770153 chr20:60521292 NA -0.33 -6.57 -0.33 1.9e-10 Body mass index; LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 8.87e-33 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg26338869 chr17:61819248 STRADA 0.58 8.63 0.42 2.34e-16 Prudent dietary pattern; LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg14671364 chr1:107599128 PRMT6 0.47 6.86 0.35 3.17e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs13631 0.728 rs7466635 chr9:139980417 T/C cg14289826 chr9:140003911 NA -0.35 -5.85 -0.3 1.13e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs826838 0.935 rs980571 chr12:39127532 C/G cg26384229 chr12:38710491 ALG10B -0.61 -8.97 -0.44 2.04e-17 Heart rate; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20929545 chr11:118958046 HMBS 0.43 6.74 0.34 6.58e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7552404 1.000 rs4949874 chr1:76161889 T/C cg22875332 chr1:76189707 ACADM 0.49 7.1 0.36 7.28e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1707322 0.752 rs4660313 chr1:46110841 A/G cg03146154 chr1:46216737 IPP -0.56 -9.62 -0.46 1.5700000000000001e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.929 rs785500 chr1:46593044 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.75 -0.34 6.35e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17106184 0.892 rs72900982 chr1:51190459 C/T cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs722599 0.715 rs2300598 chr14:75359229 T/C cg08847533 chr14:75593920 NEK9 -0.56 -9.02 -0.44 1.37e-17 IgG glycosylation; LIHC cis rs2304069 0.779 rs245050 chr5:149346960 C/G cg12661370 chr5:149340060 SLC26A2 -0.56 -7.55 -0.38 3.97e-13 HIV-1 control; LIHC cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg20607798 chr8:58055168 NA 0.69 7.41 0.37 1.01e-12 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg18538332 chr22:24372958 LOC391322 -0.6 -8.96 -0.44 2.16e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9942416 0.660 rs17563863 chr5:74998334 G/A cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC trans rs10847980 0.623 rs28501453 chr12:123877312 A/G cg07919128 chr17:18022025 MYO15A -0.75 -7.5 -0.38 5.62e-13 Adiponectin levels; LIHC cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg03060546 chr3:49711283 APEH 0.4 6.15 0.32 2.21e-9 Menarche (age at onset); LIHC cis rs7772486 0.790 rs7742333 chr6:146159029 A/G cg05347473 chr6:146136440 FBXO30 -0.36 -5.8 -0.3 1.49e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2832191 0.633 rs2832166 chr21:30462395 G/C cg08807101 chr21:30365312 RNF160 0.76 11.09 0.51 1.31e-24 Dental caries; LIHC cis rs4319547 0.695 rs6488939 chr12:122858250 T/C cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.52 -0.38 4.99e-13 Body mass index; LIHC cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.1e-10 Bipolar disorder; LIHC cis rs16958440 0.867 rs77348110 chr18:44674167 T/C cg17192377 chr18:44677553 HDHD2 0.61 6.67 0.34 1.03e-10 Sitting height ratio; LIHC cis rs17685 0.753 rs1639617 chr7:75701728 A/G cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs875971 0.789 rs10260426 chr7:65736042 G/T cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC cis rs35306767 0.903 rs12769002 chr10:927666 C/G cg20503657 chr10:835505 NA -1.34 -13.99 -0.6 1.79e-35 Eosinophil percentage of granulocytes; LIHC cis rs96067 0.711 rs272827 chr1:36627191 C/T cg24686825 chr1:36642396 MAP7D1 0.63 9.95 0.47 1.23e-20 Corneal structure; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05214676 chr4:141005085 MAML3 0.45 6.69 0.34 9.17e-11 Longevity; LIHC cis rs6088813 1.000 rs6088821 chr20:33987576 G/A cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg21821726 chr22:50170866 BRD1 -0.38 -6.21 -0.32 1.52e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs58785573 0.504 rs11947292 chr4:38634749 A/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.53 7.54 0.38 4.25e-13 Lymphocyte percentage of white cells; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg10755058 chr3:40428713 ENTPD3 -0.41 -7.23 -0.36 3.19e-12 Renal cell carcinoma; LIHC cis rs4423214 0.879 rs1790345 chr11:71145941 G/A cg05163923 chr11:71159392 DHCR7 -0.62 -8.6 -0.42 2.95e-16 Vitamin D levels; LIHC cis rs9818758 0.607 rs12715434 chr3:49295025 G/C cg07636037 chr3:49044803 WDR6 -0.81 -8.44 -0.42 9.01e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2243480 1.000 rs1267820 chr7:66050295 C/G cg18252515 chr7:66147081 NA -1.33 -18.17 -0.7 3.94e-52 Diabetic kidney disease; LIHC cis rs6754311 0.593 rs10202489 chr2:136494186 G/A cg07169764 chr2:136633963 MCM6 -0.68 -9.78 -0.47 4.41e-20 Mosquito bite size; LIHC cis rs7940866 0.774 rs10894292 chr11:130820757 C/T cg12179176 chr11:130786555 SNX19 0.53 7.73 0.39 1.18e-13 Schizophrenia; LIHC cis rs3770081 1.000 rs78646493 chr2:86283195 A/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.58 9.34 0.45 1.32e-18 Facial emotion recognition (sad faces); LIHC cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 11.46 0.53 5.76e-26 Platelet count; LIHC cis rs2075165 0.901 rs10908492 chr1:156224795 C/T cg10096929 chr1:156261403 TMEM79 0.36 5.84 0.3 1.2e-8 Tonsillectomy; LIHC cis rs2463822 1.000 rs118049526 chr11:62107508 C/T cg06239285 chr11:62104954 ASRGL1 -0.97 -6.62 -0.34 1.43e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs1005277 0.579 rs1780146 chr10:38517874 C/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.57 -0.46 2.16e-19 Extrinsic epigenetic age acceleration; LIHC cis rs509477 0.718 rs273356 chr18:32597462 A/T cg23791764 chr18:32556832 MAPRE2 0.45 6.1 0.31 2.81e-9 Cerebrospinal fluid AB1-42 levels; LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg21724239 chr8:58056113 NA -0.57 -7.47 -0.37 6.87e-13 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs1707322 0.613 rs1473840 chr1:46601197 A/G cg03146154 chr1:46216737 IPP -0.41 -6.3 -0.32 9.12e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs875971 0.545 rs75840613 chr7:65841386 G/A cg26939375 chr7:64535504 NA 0.4 6.43 0.33 4.37e-10 Aortic root size; LIHC cis rs17106184 1.000 rs1474784 chr1:50944634 C/G cg07174182 chr1:51127561 FAF1 -0.53 -6.11 -0.31 2.76e-9 Type 2 diabetes; LIHC trans rs116095464 0.558 rs6962 chr5:256509 G/A cg00938859 chr5:1591904 SDHAP3 0.58 6.57 0.33 1.83e-10 Breast cancer; LIHC cis rs898097 0.544 rs6502022 chr17:80908652 C/T cg15664640 chr17:80829946 TBCD 0.48 7.93 0.39 3.21e-14 Breast cancer; LIHC cis rs10504073 0.647 rs10504072 chr8:49993083 G/A cg00325661 chr8:49890786 NA 0.33 7.64 0.38 2.15e-13 Blood metabolite ratios; LIHC trans rs11722228 0.549 rs62288521 chr4:10099772 G/A cg26043149 chr18:55253948 FECH 0.97 14.09 0.61 7.13e-36 Gout;Urate levels;Serum uric acid levels; LIHC cis rs4925386 0.808 rs1760073 chr20:60926106 A/G cg03945807 chr20:60948434 NA -0.39 -7.11 -0.36 6.78e-12 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7412746 0.658 rs59988025 chr1:150940358 C/T cg15448220 chr1:150897856 SETDB1 0.43 6.83 0.35 3.86e-11 Melanoma; LIHC cis rs16828019 0.929 rs12037037 chr1:41698256 C/T cg03387723 chr1:41708464 SCMH1 -0.44 -7.23 -0.36 3.16e-12 Intelligence (multi-trait analysis); LIHC cis rs4575098 0.652 rs11576058 chr1:161111446 C/A cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.43 7.78 0.39 8.83e-14 Monocyte percentage of white cells; LIHC cis rs4728302 0.559 rs7779409 chr7:133158475 A/G cg10665199 chr7:133106180 EXOC4 0.52 8.72 0.43 1.24e-16 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs10751667 0.666 rs10902235 chr11:938892 T/C ch.11.42038R chr11:967971 AP2A2 0.55 10.04 0.48 5.67e-21 Alzheimer's disease (late onset); LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg00091569 chr3:40428383 ENTPD3 0.39 6.56 0.33 1.95e-10 Renal cell carcinoma; LIHC cis rs2153535 0.580 rs9328484 chr6:8524843 A/T cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.16e-16 Motion sickness; LIHC cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg21433313 chr16:3507492 NAT15 0.45 8.14 0.4 7.68e-15 Tuberculosis; LIHC cis rs7572733 0.534 rs771009 chr2:198691082 A/G cg03934865 chr2:198174659 NA 0.45 6.54 0.33 2.23e-10 Dermatomyositis; LIHC cis rs9905704 0.647 rs7221274 chr17:57008128 A/G cg12560992 chr17:57184187 TRIM37 0.68 10.03 0.48 6.56e-21 Testicular germ cell tumor; LIHC cis rs7264396 0.528 rs6058370 chr20:34518592 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.02 -0.48 6.69e-21 Total cholesterol levels; LIHC cis rs4808199 1.000 rs12972397 chr19:19562349 G/A cg03709012 chr19:19516395 GATAD2A 1.08 19.16 0.72 4.36e-56 Nonalcoholic fatty liver disease; LIHC cis rs3796352 1.000 rs11713206 chr3:52999243 A/G cg04865290 chr3:52927548 TMEM110 -0.54 -6.04 -0.31 3.95e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs12216125 0.549 rs9358905 chr6:26077839 T/A cg18357526 chr6:26021779 HIST1H4A 0.48 6.98 0.35 1.5e-11 Iron status biomarkers; LIHC cis rs15676 0.947 rs2977999 chr9:131579807 G/A cg00228799 chr9:131580591 ENDOG 0.47 7.15 0.36 5.24e-12 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01506766 chr13:46626746 ZC3H13 0.57 7.44 0.37 8.02e-13 Lung function (FEV1/FVC); LIHC cis rs2479724 0.905 rs2274578 chr6:41888827 C/G cg17623882 chr6:41773611 USP49 -0.56 -8.96 -0.44 2.15e-17 Menarche (age at onset); LIHC cis rs4268898 0.571 rs1986478 chr2:24468545 G/A cg06627628 chr2:24431161 ITSN2 -0.73 -9.76 -0.47 5.02e-20 Asthma; LIHC cis rs10193935 0.901 rs6752455 chr2:42543577 A/C cg27598129 chr2:42591480 NA -0.73 -11.25 -0.52 3.46e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs7131987 0.903 rs11050152 chr12:29404424 G/T cg05697976 chr12:29376483 FAR2 0.31 6.27 0.32 1.1e-9 QT interval; LIHC cis rs28374715 0.578 rs7165914 chr15:41632451 C/T cg18705301 chr15:41695430 NDUFAF1 -1.21 -16.78 -0.67 1.55e-46 Ulcerative colitis; LIHC cis rs2645694 0.533 rs2645674 chr4:77818202 T/C cg03477792 chr4:77819574 ANKRD56 0.6 8.79 0.43 7.59e-17 Emphysema distribution in smoking; LIHC cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg12379764 chr21:47803548 PCNT -0.59 -8.58 -0.42 3.42e-16 Testicular germ cell tumor; LIHC cis rs9457247 0.765 rs10484531 chr6:167454434 G/A cg23791538 chr6:167370224 RNASET2 -0.53 -8.13 -0.4 8.08e-15 Crohn's disease; LIHC cis rs67478160 0.619 rs12878682 chr14:104233627 G/C cg24130564 chr14:104152367 KLC1 -0.34 -5.74 -0.3 2.1e-8 Schizophrenia; LIHC cis rs3093024 0.595 rs4412174 chr6:167476066 A/G cg12798992 chr6:167411361 FGFR1OP 0.47 6.93 0.35 2.07e-11 Rheumatoid arthritis; LIHC cis rs7927771 1.000 rs10838747 chr11:47716324 G/C cg20307385 chr11:47447363 PSMC3 -0.44 -5.77 -0.3 1.76e-8 Subjective well-being; LIHC cis rs7224737 0.750 rs12325861 chr17:40289412 T/C cg20291162 chr17:40259547 DHX58 -0.42 -5.9 -0.3 8.8e-9 Fibrinogen levels; LIHC cis rs35883536 1.000 rs2050472 chr1:101125560 T/C cg14515779 chr1:101123966 NA -0.7 -14.11 -0.61 6e-36 Monocyte count; LIHC cis rs796364 0.906 rs281784 chr2:200749749 T/A cg23649088 chr2:200775458 C2orf69 0.49 5.85 0.3 1.18e-8 Schizophrenia; LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg15382696 chr6:118971807 C6orf204 0.63 6.37 0.33 6.05e-10 Diastolic blood pressure; LIHC cis rs12291225 0.679 rs11369 chr11:14288096 A/G cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.18e-31 Sense of smell; LIHC cis rs1707322 0.686 rs3014236 chr1:46091305 T/C cg06784218 chr1:46089804 CCDC17 -0.43 -8.04 -0.4 1.43e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs34192067 chr7:65887657 C/A cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC cis rs7903847 0.602 rs7916665 chr10:99157573 T/G cg08345082 chr10:99160200 RRP12 -0.39 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11971779 0.711 rs6961204 chr7:139047399 T/G cg07862535 chr7:139043722 LUC7L2 0.66 10.63 0.5 5.27e-23 Diisocyanate-induced asthma; LIHC trans rs916888 0.773 rs199534 chr17:44824213 T/G cg12297030 chr17:43662878 NA -0.65 -6.24 -0.32 1.27e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9790314 0.659 rs13066683 chr3:160847410 A/G cg03342759 chr3:160939853 NMD3 -0.71 -9.68 -0.46 9.29e-20 Morning vs. evening chronotype; LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg22903471 chr2:27725779 GCKR -0.52 -8.96 -0.44 2.18e-17 Total body bone mineral density; LIHC cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs9457247 1.000 rs389956 chr6:167407254 T/G cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.51 1.09e-24 Crohn's disease; LIHC cis rs7772486 0.641 rs2777485 chr6:146334377 G/A cg05347473 chr6:146136440 FBXO30 0.46 7.01 0.35 1.31e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs2727020 0.796 rs7131672 chr11:49274421 A/C cg15704280 chr7:45808275 SEPT13 0.76 10.97 0.51 3.3e-24 Coronary artery disease; LIHC cis rs8180040 0.800 rs11130126 chr3:47306894 A/G cg27129171 chr3:47204927 SETD2 -0.56 -9.11 -0.44 6.87e-18 Colorectal cancer; LIHC cis rs9649213 0.593 rs13246843 chr7:98002661 G/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.71 0.34 8.06e-11 Bipolar disorder; LIHC cis rs68170813 0.559 rs10953532 chr7:106881808 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg00128877 chr1:47070178 MKNK1 -0.49 -6.42 -0.33 4.43e-10 Facial morphology (factor 20); LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg03354898 chr7:1950403 MAD1L1 -0.36 -5.71 -0.3 2.4e-8 Bipolar disorder and schizophrenia; LIHC trans rs911555 0.617 rs7156036 chr14:103908142 A/G cg17675199 chr6:35436792 RPL10A -0.45 -9.33 -0.45 1.39e-18 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05972000 chr8:67525501 MYBL1 -0.46 -6.34 -0.32 7.47e-10 Pancreatic cancer; LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg08677398 chr8:58056175 NA -0.39 -6.1 -0.31 2.83e-9 Developmental language disorder (linguistic errors); LIHC cis rs1059312 0.808 rs900982 chr12:129304369 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.78 -16.8 -0.67 1.27e-46 Systemic lupus erythematosus; LIHC cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg01448562 chr3:133502909 NA -0.41 -6.31 -0.32 8.58e-10 Iron status biomarkers; LIHC cis rs801193 1.000 rs11773829 chr7:66141074 G/A cg18876405 chr7:65276391 NA -0.43 -7.45 -0.37 7.54e-13 Aortic root size; LIHC cis rs7546668 1.000 rs4233534 chr1:15842329 C/T cg11706911 chr1:15910989 AGMAT 0.45 6.96 0.35 1.7e-11 Glomerular filtration rate (creatinine); LIHC trans rs916888 0.773 rs199439 chr17:44793503 A/G cg16836995 chr17:43662488 NA -0.76 -7.78 -0.39 8.76e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1580019 0.921 rs1580023 chr7:32497881 G/A cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs4969178 0.622 rs4129767 chr17:76403984 G/A cg20026190 chr17:76395443 PGS1 0.39 5.82 0.3 1.37e-8 HDL cholesterol levels; LIHC cis rs2836950 0.520 rs11911087 chr21:40665192 G/A cg06238570 chr21:40685208 BRWD1 -0.44 -7.19 -0.36 4.22e-12 Menarche (age at onset); LIHC cis rs7224685 0.569 rs7221595 chr17:4007594 C/T cg09597638 chr17:3907349 NA -0.5 -6.04 -0.31 3.92e-9 Type 2 diabetes; LIHC cis rs892961 0.932 rs11650011 chr17:75412334 A/G cg05865280 chr17:75406074 SEPT9 0.62 12.81 0.57 6.12e-31 Airflow obstruction; LIHC cis rs2153535 0.580 rs9392220 chr6:8457946 G/A cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs1163251 0.837 rs839612 chr1:120247176 T/C cg19096424 chr1:120255104 PHGDH 0.63 8.1 0.4 9.82e-15 Blood metabolite levels; LIHC cis rs1198430 1.000 rs1198432 chr1:23756155 C/T cg13183780 chr1:23809682 ASAP3 0.54 7.73 0.39 1.23e-13 Total cholesterol levels; LIHC trans rs2243480 0.803 rs13224048 chr7:65993766 G/A cg07424592 chr7:64974309 NA 0.78 8.95 0.44 2.26e-17 Diabetic kidney disease; LIHC cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.43 7.23 0.36 3.09e-12 Electroencephalogram traits; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg07725925 chr16:89976287 TCF25 0.41 5.77 0.3 1.74e-8 Skin colour saturation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01078248 chr7:123197661 NDUFA5 0.46 6.34 0.32 7.37e-10 Pancreatic cancer; LIHC cis rs7072216 0.727 rs7915108 chr10:100164441 T/C cg26618903 chr10:100175079 PYROXD2 -0.39 -6.37 -0.33 5.97e-10 Metabolite levels; LIHC cis rs4604732 0.578 rs12040725 chr1:247644697 T/A cg02104434 chr1:247694406 LOC148824;OR2C3 0.25 6.02 0.31 4.43e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg15383120 chr6:291909 DUSP22 -0.52 -7.26 -0.37 2.55e-12 Menopause (age at onset); LIHC cis rs17685 0.712 rs7778735 chr7:75770237 T/C cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35110281 0.811 rs9980185 chr21:45057905 A/G cg04455712 chr21:45112962 RRP1B 0.36 5.99 0.31 5.27e-9 Mean corpuscular volume; LIHC cis rs892961 0.932 rs7224116 chr17:75413177 A/G cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs787274 0.718 rs4979173 chr9:115627699 A/C cg13803584 chr9:115635662 SNX30 -0.64 -7.34 -0.37 1.57e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6570726 0.935 rs12663205 chr6:145818378 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.77 0.47 4.63e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.935 rs11624890 chr14:90738165 T/A cg14092571 chr14:90743983 NA 0.46 7.33 0.37 1.72e-12 Mortality in heart failure; LIHC cis rs12477438 0.520 rs6739579 chr2:99731552 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.88 15.8 0.65 1.34e-42 Chronic sinus infection; LIHC cis rs74181299 0.750 rs12472718 chr2:65327620 G/A cg05010058 chr2:65284262 CEP68 -0.39 -6.6 -0.34 1.6e-10 Pulse pressure; LIHC cis rs8067354 0.540 rs1051424 chr17:58024324 A/G cg02344993 chr17:57696989 CLTC 0.66 10.24 0.48 1.26e-21 Hemoglobin concentration; LIHC cis rs7000551 0.778 rs2469760 chr8:22365945 A/G cg12081754 chr8:22256438 SLC39A14 0.44 7.01 0.35 1.3e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1707322 0.638 rs1707302 chr1:46600917 A/G cg03146154 chr1:46216737 IPP -0.41 -6.52 -0.33 2.48e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6815814 0.898 rs5743562 chr4:38806096 T/C cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC cis rs1348850 0.831 rs7606235 chr2:178401288 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.87 13.48 0.59 1.61e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg13152130 chr6:118910203 C6orf204 0.59 7.32 0.37 1.84e-12 Diastolic blood pressure; LIHC cis rs8027181 0.839 rs4777532 chr15:73041767 A/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 8.01 0.4 1.78e-14 Triglyceride levels; LIHC cis rs6500602 0.592 rs4785966 chr16:4518754 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 -0.43 -6.01 -0.31 4.83e-9 Schizophrenia; LIHC cis rs7772486 0.790 rs2250387 chr6:146205233 C/T cg13319975 chr6:146136371 FBXO30 -0.35 -5.8 -0.3 1.53e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7945705 0.935 rs2653593 chr11:8877317 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.53 -9.53 -0.46 3.01e-19 Hemoglobin concentration; LIHC cis rs11122272 0.735 rs2437149 chr1:231490105 C/T cg06096015 chr1:231504339 EGLN1 0.49 9.14 0.44 5.73e-18 Hemoglobin concentration; LIHC cis rs561341 1.000 rs8064843 chr17:30245744 A/G cg13647721 chr17:30228624 UTP6 0.7 6.93 0.35 2.14e-11 Hip circumference adjusted for BMI; LIHC trans rs6073597 1.000 rs6031980 chr20:43714384 C/T cg01098656 chr10:1095069 IDI1 0.44 6.17 0.32 1.9e-9 Positive affect; LIHC cis rs11711311 1.000 rs28394480 chr3:113485143 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.94 -0.35 2e-11 IgG glycosylation; LIHC cis rs7336332 0.598 rs77055070 chr13:28010516 C/G cg22138327 chr13:27999177 GTF3A 0.5 5.73 0.3 2.2e-8 Weight; LIHC cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg02931644 chr1:25747376 RHCE 0.35 7.72 0.39 1.28e-13 Erythrocyte sedimentation rate; LIHC cis rs9611565 0.559 rs1006407 chr22:41972032 T/C cg03806693 chr22:41940476 POLR3H -1.14 -11.79 -0.54 3.61e-27 Vitiligo; LIHC cis rs10504229 0.593 rs113184543 chr8:58042950 A/G cg20607798 chr8:58055168 NA 0.45 6.25 0.32 1.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs992157 0.965 rs62182826 chr2:219148723 C/A cg20019365 chr2:219134978 PNKD;AAMP 0.81 13.04 0.58 7.89e-32 Colorectal cancer; LIHC cis rs12602486 1.000 rs74635090 chr17:42219267 G/A cg08193365 chr17:42277699 NA 1.08 7.74 0.39 1.12e-13 Glycated hemoglobin levels; LIHC cis rs7131987 0.622 rs7294598 chr12:29531989 A/C cg14222432 chr12:29376421 FAR2 -0.36 -6.95 -0.35 1.89e-11 QT interval; LIHC cis rs10540 1.000 rs61876332 chr11:487101 C/T cg03576123 chr11:487126 PTDSS2 -1.0 -7.64 -0.38 2.18e-13 Body mass index; LIHC cis rs6684514 1.000 rs10908498 chr1:156278175 T/C cg16558208 chr1:156270281 VHLL 0.54 10.19 0.48 1.76e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7131987 0.683 rs7954278 chr12:29459290 G/A cg00204748 chr12:29376779 FAR2 0.38 7.02 0.35 1.2e-11 QT interval; LIHC cis rs7909074 0.798 rs914699 chr10:45377066 A/C cg05187965 chr10:45406764 TMEM72 -0.27 -6.65 -0.34 1.17e-10 Mean corpuscular volume; LIHC cis rs4700695 0.925 rs414001 chr5:65383259 C/G cg21114390 chr5:65439923 SFRS12 -0.46 -6.02 -0.31 4.39e-9 Facial morphology (factor 19); LIHC cis rs2073499 0.872 rs58051625 chr3:50278717 G/C cg03645007 chr3:50255295 SLC38A3 0.52 6.36 0.33 6.5e-10 Schizophrenia; LIHC cis rs921968 0.643 rs600057 chr2:219456737 A/G cg17980119 chr2:219472607 PLCD4 0.34 5.88 0.3 9.92e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs17539620 0.628 rs62432729 chr6:154830044 T/C cg20019720 chr6:154832845 CNKSR3 0.44 6.49 0.33 2.97e-10 Lipoprotein (a) levels; LIHC cis rs780096 0.546 rs8179225 chr2:27737181 A/G cg21747090 chr2:27597821 SNX17 -0.43 -6.2 -0.32 1.64e-9 Total body bone mineral density; LIHC cis rs1670533 1.000 rs6839931 chr4:1053172 A/G cg27284194 chr4:1044797 NA 0.6 8.82 0.43 6.08e-17 Recombination rate (females); LIHC cis rs7666738 0.830 rs11941961 chr4:99065654 G/T cg05340658 chr4:99064831 C4orf37 0.71 13.02 0.58 9.36e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC cis rs17685 0.672 rs6465011 chr7:75811297 T/C cg04610667 chr7:75704037 NA -0.35 -6.3 -0.32 8.94e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10411936 0.626 rs8109817 chr19:16587889 T/C cg10248733 chr19:16607483 C19orf44;CALR3 0.51 6.81 0.35 4.36e-11 White blood cell count;Multiple sclerosis; LIHC cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.71 0.38 1.43e-13 Bipolar disorder; LIHC cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg11663144 chr21:46675770 NA -0.34 -6.2 -0.32 1.66e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs17253792 0.915 rs28663681 chr14:56178820 A/T cg01858014 chr14:56050164 KTN1 -0.75 -7.41 -0.37 9.7e-13 Putamen volume; LIHC cis rs9303401 0.659 rs12944971 chr17:56988801 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.95 12.92 0.57 2.24e-31 Cognitive test performance; LIHC cis rs6762 0.719 rs1130698 chr11:838542 C/T cg16425592 chr11:842748 TSPAN4;POLR2L -0.75 -8.79 -0.43 7.64e-17 Mean platelet volume; LIHC cis rs7020830 0.931 rs7851239 chr9:37138672 A/G cg14294708 chr9:37120828 ZCCHC7 -1.04 -19.32 -0.72 9.92e-57 Schizophrenia; LIHC cis rs7772486 0.875 rs9403763 chr6:146357655 A/G cg05347473 chr6:146136440 FBXO30 0.37 5.95 0.31 6.49e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8060686 0.545 rs12597573 chr16:68167521 A/C cg05110241 chr16:68378359 PRMT7 0.6 6.5 0.33 2.8e-10 HDL cholesterol;Metabolic syndrome; LIHC trans rs783540 0.867 rs10906984 chr15:83366296 A/C cg18393722 chr15:85113863 UBE2QP1 0.39 6.84 0.35 3.65e-11 Schizophrenia; LIHC cis rs7191439 0.790 rs2306046 chr16:88781419 A/G cg02389323 chr16:88786976 FAM38A 0.77 7.09 0.36 7.55e-12 Plateletcrit; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11995801 chr2:232826275 DIS3L2 -0.5 -6.47 -0.33 3.45e-10 Systolic blood pressure; LIHC cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg02290350 chr8:58132656 NA 0.46 9.17 0.44 4.46e-18 Developmental language disorder (linguistic errors); LIHC trans rs3118233 1 rs3118233 chr16:68733646 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.64 -9.72 -0.47 6.79e-20 Red cell distribution width; LIHC cis rs5753618 0.561 rs9606831 chr22:31732512 C/T cg22777020 chr22:31556080 RNF185 0.55 6.38 0.33 5.81e-10 Colorectal cancer; LIHC cis rs992157 0.687 rs35271699 chr2:219117482 G/A cg00012203 chr2:219082015 ARPC2 0.91 16.41 0.66 4.78e-45 Colorectal cancer; LIHC cis rs892961 0.932 rs312853 chr17:75406045 T/G cg01320579 chr17:75405842 SEPT9 0.51 8.91 0.43 2.98e-17 Airflow obstruction; LIHC cis rs763121 0.853 rs5750671 chr22:39094619 A/C cg06022373 chr22:39101656 GTPBP1 0.74 14.71 0.62 2.82e-38 Menopause (age at onset); LIHC cis rs3824867 0.920 rs7101772 chr11:47449378 A/G cg20307385 chr11:47447363 PSMC3 -0.58 -7.89 -0.39 4.24e-14 Mean corpuscular hemoglobin; LIHC cis rs2569991 0.588 rs2596909 chr3:12928672 G/C cg22481960 chr3:13008800 IQSEC1 -0.42 -7.29 -0.37 2.23e-12 Periodontitis (DPAL); LIHC cis rs7927771 0.542 rs7122217 chr11:47777920 G/C cg20307385 chr11:47447363 PSMC3 -0.65 -9.85 -0.47 2.68e-20 Subjective well-being; LIHC cis rs1113500 0.799 rs1777459 chr1:108584999 G/C cg06207961 chr1:108661230 NA -0.37 -7.2 -0.36 3.86e-12 Growth-regulated protein alpha levels; LIHC cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg17554472 chr22:41940697 POLR3H -0.55 -5.95 -0.31 6.47e-9 Vitiligo; LIHC cis rs1559088 0.600 rs7255229 chr19:33562807 A/G cg17764715 chr19:33622953 WDR88 0.54 7.19 0.36 4.22e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg13957321 chr17:43675089 NA 0.45 7.24 0.36 3.07e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6450176 1.000 rs5024170 chr5:53300827 C/A ch.5.1024479R chr5:53302184 ARL15 -0.81 -14.69 -0.62 3.22e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs35110281 0.805 rs2838318 chr21:44991825 G/A cg04455712 chr21:45112962 RRP1B 0.42 7.34 0.37 1.53e-12 Mean corpuscular volume; LIHC cis rs35110281 0.805 rs2838317 chr21:44991791 A/C cg21573476 chr21:45109991 RRP1B -0.53 -10.03 -0.48 6.12e-21 Mean corpuscular volume; LIHC cis rs921968 0.643 rs526134 chr2:219402371 G/A cg17980119 chr2:219472607 PLCD4 0.35 6.02 0.31 4.62e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs10028773 0.700 rs7671797 chr4:120248157 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.35 0.41 1.74e-15 Educational attainment; LIHC cis rs4819052 0.851 rs2236444 chr21:46678226 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.36 0.52 1.32e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10193935 0.792 rs13430031 chr2:42499968 C/T cg27598129 chr2:42591480 NA -0.7 -10.52 -0.49 1.32e-22 Colonoscopy-negative controls vs population controls; LIHC trans rs61332075 0.518 rs72994950 chr2:239422993 T/C cg01134436 chr17:81009848 B3GNTL1 0.76 6.53 0.33 2.44e-10 Lung function (FEV1/FVC); LIHC cis rs1552244 0.882 rs7633769 chr3:10020622 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.95 0.47 1.22e-20 Alzheimer's disease; LIHC cis rs8060686 0.545 rs8056649 chr16:68260083 A/G cg09835421 chr16:68378352 PRMT7 0.47 5.78 0.3 1.72e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs7617773 0.963 rs12495221 chr3:48179178 C/T cg11946769 chr3:48343235 NME6 -0.56 -7.64 -0.38 2.18e-13 Coronary artery disease; LIHC cis rs769267 0.831 rs2872878 chr19:19480521 G/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.52 -7.84 -0.39 5.66e-14 Tonsillectomy; LIHC cis rs7633770 0.710 rs4683259 chr3:46698538 A/G cg11219411 chr3:46661640 NA -0.39 -6.64 -0.34 1.21e-10 Coronary artery disease; LIHC cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg24004478 chr7:855632 UNC84A 0.49 8.05 0.4 1.41e-14 Perceived unattractiveness to mosquitoes; LIHC cis rs2932538 0.922 rs7535636 chr1:113101799 C/T cg22162597 chr1:113214053 CAPZA1 -0.69 -10.63 -0.5 5.56e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs61990749 0.511 rs2052444 chr14:78312918 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.49 7.9 0.39 3.89e-14 Fibroblast growth factor basic levels; LIHC cis rs1577917 1.000 rs2812972 chr6:86669880 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.69 -0.38 1.54e-13 Response to antipsychotic treatment; LIHC cis rs7572733 0.576 rs1368989 chr2:198937082 T/C cg10820045 chr2:198174542 NA 0.42 6.15 0.32 2.18e-9 Dermatomyositis; LIHC cis rs769267 0.965 rs12460764 chr19:19431963 G/T cg03709012 chr19:19516395 GATAD2A -0.91 -15.52 -0.64 1.65e-41 Tonsillectomy; LIHC cis rs2816062 0.965 rs2816061 chr1:18903819 A/G cg18795169 chr1:18902165 NA 0.75 15.96 0.65 3.13e-43 Urate levels in lean individuals; LIHC cis rs7312933 0.533 rs3747557 chr12:42717961 G/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.02 -0.4 1.66e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg03264133 chr6:25882463 NA -0.62 -8.88 -0.43 3.86e-17 Blood metabolite levels; LIHC cis rs2370759 1.000 rs2769241 chr10:32556229 T/C cg18270830 chr10:32634957 EPC1 -0.54 -6.67 -0.34 1.05e-10 Sexual dysfunction (female); LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg06420487 chr17:61919686 SMARCD2 0.42 5.76 0.3 1.88e-8 Height; LIHC cis rs4713118 0.621 rs9295756 chr6:28033396 G/T cg16479474 chr6:28041457 NA 0.45 6.49 0.33 3.07e-10 Parkinson's disease; LIHC trans rs11098499 0.618 rs6858383 chr4:120296772 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs769267 0.930 rs747050 chr19:19584987 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.93 0.39 3.07e-14 Tonsillectomy; LIHC cis rs10540 0.908 rs35608427 chr11:498976 T/C cg03576123 chr11:487126 PTDSS2 -1.12 -8.4 -0.41 1.17e-15 Body mass index; LIHC cis rs9649213 0.613 rs2286074 chr7:97952011 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs67460515 0.892 rs7610985 chr3:161062848 G/A cg17135325 chr3:160939158 NMD3 0.52 7.29 0.37 2.17e-12 Parkinson's disease; LIHC trans rs4650994 0.525 rs2811295 chr1:178551267 C/T cg05059571 chr16:84539110 KIAA1609 0.43 7.3 0.37 2.06e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1707322 0.752 rs4586014 chr1:46150443 A/G cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.36e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs916888 0.773 rs199443 chr17:44819565 C/T cg22968622 chr17:43663579 NA 1.17 13.02 0.58 9.42e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs943466 0.793 rs59137082 chr6:33732365 C/T cg25922239 chr6:33757077 LEMD2 -0.46 -5.73 -0.3 2.24e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs34779708 0.931 rs12768019 chr10:35389843 T/C cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs8062405 0.965 rs56040780 chr16:28861881 C/T cg00204512 chr16:28754710 NA 0.34 6.3 0.32 9.35e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs826838 1.000 rs11183214 chr12:38692938 C/T cg26384229 chr12:38710491 ALG10B 1.06 14.92 0.63 3.95e-39 Heart rate; LIHC trans rs35110281 0.592 rs6417729 chr21:44967202 A/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.19 0.32 1.7e-9 Mean corpuscular volume; LIHC trans rs7867456 0.546 rs10757178 chr9:21046674 A/G cg08478193 chr16:27561459 GTF3C1;KIAA0556 0.47 6.67 0.34 1.02e-10 Axial length; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg11766577 chr21:47581405 C21orf56 -0.43 -7.02 -0.35 1.23e-11 Testicular germ cell tumor; LIHC cis rs2637030 0.559 rs549131 chr5:52902238 T/C cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.26e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs72653721 0.877 rs72653723 chr6:10976218 G/A cg13562911 chr6:11044106 ELOVL2 0.51 7.1 0.36 7.37e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs9457247 0.765 rs1060404 chr6:167429467 A/G cg12798992 chr6:167411361 FGFR1OP 0.48 7.37 0.37 1.32e-12 Crohn's disease; LIHC cis rs1881396 0.783 rs10181342 chr2:27757343 A/G cg27432699 chr2:27873401 GPN1 0.46 6.88 0.35 2.92e-11 Nonalcoholic fatty liver disease; LIHC trans rs9951602 0.512 rs6506868 chr18:76642559 C/G cg02800362 chr5:177631904 HNRNPAB 0.64 10.23 0.48 1.36e-21 Obesity-related traits; LIHC cis rs11690935 0.655 rs12997093 chr2:172564438 A/G cg13550731 chr2:172543902 DYNC1I2 0.62 11.7 0.53 7.92e-27 Schizophrenia; LIHC cis rs6547741 1.000 rs4665381 chr2:27757150 A/C cg27432699 chr2:27873401 GPN1 0.71 11.33 0.52 1.7e-25 Oral cavity cancer; LIHC cis rs1451375 1.000 rs4452748 chr7:50625056 A/C cg14593290 chr7:50529359 DDC -0.39 -6.51 -0.33 2.72e-10 Malaria; LIHC cis rs7582720 0.832 rs114139737 chr2:203721733 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.03 0.31 4.17e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7914558 0.966 rs10748835 chr10:104660256 C/T cg15744005 chr10:104629667 AS3MT -0.42 -9.52 -0.46 3.2e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs72781680 0.566 rs55987381 chr2:23900938 T/C cg08917208 chr2:24149416 ATAD2B 0.63 6.18 0.32 1.85e-9 Lymphocyte counts; LIHC cis rs3859192 0.599 rs2227319 chr17:38170845 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.91 0.65 4.59e-43 White blood cell count; LIHC cis rs9916302 0.861 rs2338801 chr17:37490780 G/T cg07936489 chr17:37558343 FBXL20 0.84 13.51 0.59 1.24e-33 Glomerular filtration rate (creatinine); LIHC trans rs916888 0.773 rs199445 chr17:44817408 C/T cg22968622 chr17:43663579 NA 1.17 13.02 0.58 9.42e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1144333 0.510 rs12408897 chr1:76448102 T/C cg10523679 chr1:76189770 ACADM 0.44 5.91 0.3 8.5e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg08392591 chr16:89556376 ANKRD11 0.54 8.65 0.42 1.99e-16 Multiple myeloma (IgH translocation); LIHC cis rs2070488 0.965 rs6599209 chr3:38558197 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.5 -0.62 1.81e-37 Electrocardiographic conduction measures; LIHC cis rs796364 0.806 rs12616905 chr2:201007764 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg12310025 chr6:25882481 NA 0.6 7.19 0.36 4e-12 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.552 rs1030765 chr2:136553188 A/T cg07169764 chr2:136633963 MCM6 -0.7 -9.78 -0.47 4.5e-20 Mosquito bite size; LIHC cis rs62034325 0.697 rs710410 chr16:28603342 A/G cg07451762 chr16:28383216 NA 0.41 7.05 0.36 9.65e-12 Body mass index; LIHC trans rs1814175 0.616 rs4881723 chr11:49788566 G/T cg18944383 chr4:111397179 ENPEP 0.27 6.96 0.35 1.78e-11 Height; LIHC cis rs35306767 0.903 rs12761424 chr10:967295 C/T cg26597838 chr10:835615 NA 0.96 11.79 0.54 3.72e-27 Eosinophil percentage of granulocytes; LIHC cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg17971929 chr21:40555470 PSMG1 0.83 10.01 0.48 7.48e-21 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01185801 chr11:65265397 MALAT1 0.44 6.36 0.33 6.56e-10 Pancreatic cancer; LIHC cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg12311346 chr5:56204834 C5orf35 -0.58 -7.6 -0.38 2.92e-13 Initial pursuit acceleration; LIHC cis rs11958404 0.860 rs72818136 chr5:157462866 C/T cg05962755 chr5:157440814 NA 1.01 11.11 0.52 1.05e-24 IgG glycosylation; LIHC cis rs2280018 0.609 rs2941253 chr16:15173746 G/A cg27102117 chr16:15229624 NA 0.28 6.01 0.31 4.71e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg20870372 chr13:99867982 UBAC2 0.37 6.32 0.32 8.25e-10 Bilirubin levels; LIHC cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg12463550 chr7:65579703 CRCP 0.68 7.05 0.36 9.9e-12 Diabetic kidney disease; LIHC cis rs13118159 0.872 rs3903127 chr4:1348806 A/C cg13395646 chr4:1353034 KIAA1530 -0.69 -9.52 -0.46 3.16e-19 Longevity; LIHC cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg12463550 chr7:65579703 CRCP 0.67 7.03 0.36 1.15e-11 Diabetic kidney disease; LIHC cis rs1046896 0.512 rs3785513 chr17:80886748 G/A cg02711726 chr17:80685570 FN3KRP -0.38 -7.16 -0.36 5.02e-12 Glycated hemoglobin levels; LIHC cis rs6582630 0.537 rs66855609 chr12:38299029 T/C cg26384229 chr12:38710491 ALG10B 0.58 8.16 0.4 6.61e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs116095464 0.558 rs9312956 chr5:201812 T/C cg22857025 chr5:266934 NA -1.63 -16.46 -0.66 2.95e-45 Breast cancer; LIHC cis rs7089973 0.624 rs11196940 chr10:116593791 T/G cg03647239 chr10:116582469 FAM160B1 0.44 6.41 0.33 4.82e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs611744 0.647 rs1379336 chr8:109276606 G/T cg21045802 chr8:109455806 TTC35 0.6 10.47 0.49 1.92e-22 Dupuytren's disease; LIHC cis rs9649465 0.561 rs600420 chr7:123408050 G/A cg03229431 chr7:123269106 ASB15 0.43 9.2 0.45 3.55e-18 Migraine; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg22528358 chr1:107598549 PRMT6 -0.71 -11.82 -0.54 2.78e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11212260 0.655 rs7122872 chr11:107340702 C/G cg25435332 chr11:107328525 CWF19L2 0.84 8.24 0.41 3.8e-15 IgG glycosylation; LIHC cis rs9549367 0.713 rs9549691 chr13:113861606 A/C cg00898013 chr13:113819073 PROZ -0.47 -7.54 -0.38 4.33e-13 Platelet distribution width; LIHC cis rs9549260 0.755 rs9549252 chr13:41230141 A/G cg21288729 chr13:41239152 FOXO1 0.62 10.06 0.48 4.84e-21 Red blood cell count; LIHC cis rs17376456 0.741 rs10036829 chr5:93309897 G/C cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs7903847 0.642 rs11189175 chr10:99139609 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.64 -0.34 1.24e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs748404 0.697 rs530188 chr15:43545314 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.3 0.41 2.52e-15 Lung cancer; LIHC cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg10862848 chr6:42927986 GNMT -0.27 -6.39 -0.33 5.58e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9611565 0.512 rs139566 chr22:42199277 A/G cg06634786 chr22:41940651 POLR3H -0.75 -7.8 -0.39 7.39e-14 Vitiligo; LIHC cis rs1185460 0.565 rs538478 chr11:118925341 C/T cg23280166 chr11:118938394 VPS11 -0.51 -7.08 -0.36 7.98e-12 Coronary artery disease; LIHC cis rs7605378 0.658 rs4673507 chr2:200710167 G/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.44 5.87 0.3 1.04e-8 Osteoporosis; LIHC cis rs2637030 0.533 rs2607511 chr5:52930471 G/A cg06476337 chr5:52856530 NDUFS4 0.43 6.82 0.35 4.25e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs6502050 0.835 rs3935816 chr17:80137173 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.9 -0.3 8.72e-9 Life satisfaction; LIHC cis rs11122272 0.735 rs2250704 chr1:231486647 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.32 0.45 1.45e-18 Hemoglobin concentration; LIHC cis rs10876993 0.890 rs810204 chr12:58075733 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.16 -0.32 2.06e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs732505 1.000 rs8111720 chr19:5585823 A/G cg26242866 chr19:5711310 LONP1 0.86 6.31 0.32 8.52e-10 vWF and FVIII levels; LIHC cis rs796364 0.806 rs35200468 chr2:201110368 G/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.63 -6.73 -0.34 7.12e-11 Schizophrenia; LIHC cis rs2073300 1.000 rs6137962 chr20:23443966 T/C cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2845885 0.744 rs3802932 chr11:63988045 G/A cg05555928 chr11:63887634 MACROD1 -0.52 -6.48 -0.33 3.24e-10 Body mass index; LIHC cis rs4803468 1.000 rs284649 chr19:41926838 C/T cg09537434 chr19:41945824 ATP5SL -1.03 -21.43 -0.76 3.5e-65 Height; LIHC cis rs10540 1.000 rs116101630 chr11:506826 G/C cg03352830 chr11:487213 PTDSS2 0.79 6.79 0.34 4.85e-11 Body mass index; LIHC cis rs9814567 1.000 rs4974483 chr3:134219001 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs892961 0.899 rs72896163 chr17:75412525 C/T cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs11122272 0.735 rs2486730 chr1:231534987 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.94e-23 Hemoglobin concentration; LIHC cis rs1670533 1.000 rs629261 chr4:1086763 A/C cg27284194 chr4:1044797 NA 0.61 8.99 0.44 1.72e-17 Recombination rate (females); LIHC cis rs67478160 0.643 rs34813623 chr14:104263294 A/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.86 0.57 3.97e-31 Schizophrenia; LIHC cis rs950776 0.518 rs11632604 chr15:78821914 T/C cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs9549367 0.713 rs3024776 chr13:113827075 A/G cg18105134 chr13:113819100 PROZ 0.77 13.28 0.58 9.45e-33 Platelet distribution width; LIHC cis rs3741404 0.825 rs2515241 chr11:63975331 C/T cg04317338 chr11:64019027 PLCB3 0.48 6.72 0.34 7.41e-11 Platelet count; LIHC cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg06697600 chr4:7070879 GRPEL1 -0.66 -10.7 -0.5 3.02e-23 Monocyte percentage of white cells; LIHC cis rs7178375 1.000 rs7169064 chr15:31210862 C/T cg19680485 chr15:31195859 MTMR15 -0.55 -6.07 -0.31 3.46e-9 Hypertriglyceridemia; LIHC cis rs67981189 0.593 rs221926 chr14:71579135 A/C cg15816911 chr14:71606274 NA -0.41 -6.58 -0.34 1.76e-10 Schizophrenia; LIHC cis rs4803468 1.000 rs13344563 chr19:41945904 G/C cg09537434 chr19:41945824 ATP5SL 1.02 21.05 0.75 1.07e-63 Height; LIHC cis rs35306767 0.715 rs17221463 chr10:1038040 T/C cg26597838 chr10:835615 NA 0.9 8.47 0.42 7.52e-16 Eosinophil percentage of granulocytes; LIHC cis rs344364 0.518 rs1657129 chr16:1945826 G/A cg26897989 chr16:1907736 C16orf73 -0.46 -5.77 -0.3 1.82e-8 Glomerular filtration rate in chronic kidney disease; LIHC cis rs5769765 0.908 rs9616370 chr22:50306316 A/G cg09182678 chr22:50328711 NA 0.44 6.38 0.33 5.72e-10 Schizophrenia; LIHC cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg06618935 chr21:46677482 NA -0.3 -5.72 -0.3 2.35e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs240764 0.717 rs6904959 chr6:101157916 C/T cg09795085 chr6:101329169 ASCC3 -0.48 -6.94 -0.35 1.99e-11 Neuroticism; LIHC cis rs1707322 1.000 rs4524994 chr1:46370263 A/G cg06784218 chr1:46089804 CCDC17 0.34 6.04 0.31 4.06e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs60871478 1.000 rs34086011 chr7:805430 C/T cg13844804 chr7:814759 HEATR2 0.44 5.95 0.31 6.72e-9 Cerebrospinal P-tau181p levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg24378253 chr1:1017383 C1orf159 0.43 6.51 0.33 2.69e-10 Bilirubin levels; LIHC cis rs2334880 0.678 rs12922830 chr16:71447270 C/T cg06353428 chr16:71660113 MARVELD3 -0.78 -7.87 -0.39 4.87e-14 Malaria; LIHC cis rs2115536 0.692 rs8036559 chr15:80170563 C/T cg11839771 chr15:80205821 ST20 -0.32 -6.92 -0.35 2.21e-11 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs7937890 0.732 rs7946902 chr11:14273308 C/T cg02886208 chr11:14281011 SPON1 0.57 8.36 0.41 1.61e-15 Mitochondrial DNA levels; LIHC cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg10295955 chr4:187884368 NA -0.97 -22.79 -0.78 1.36e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg10755058 chr3:40428713 ENTPD3 -0.42 -7.25 -0.36 2.8e-12 Renal cell carcinoma; LIHC cis rs6442522 0.678 rs924813 chr3:15512799 A/T cg16303742 chr3:15540471 COLQ 0.44 7.31 0.37 1.89e-12 Uric acid levels; LIHC cis rs903552 0.935 rs12907726 chr15:102003626 C/G cg00659931 chr15:102010125 PCSK6 -0.44 -6.04 -0.31 4.03e-9 Diabetic kidney disease; LIHC trans rs10838798 0.504 rs11039627 chr11:48293931 C/T cg15704280 chr7:45808275 SEPT13 -0.42 -6.33 -0.32 7.86e-10 Height; LIHC cis rs950169 0.544 rs2036949 chr15:85163605 T/C cg03959625 chr15:84868606 LOC388152 0.44 6.12 0.31 2.54e-9 Schizophrenia; LIHC cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg02503808 chr4:7069936 GRPEL1 0.75 11.24 0.52 3.59e-25 Monocyte percentage of white cells; LIHC cis rs2455799 0.573 rs2255248 chr3:15754849 A/G cg12698662 chr3:15914712 MIR563 0.4 7.34 0.37 1.54e-12 Mean platelet volume; LIHC cis rs2386661 0.547 rs11259540 chr10:5646706 A/T cg17085576 chr10:5658249 NA -0.35 -6.2 -0.32 1.66e-9 Breast cancer; LIHC cis rs9549328 0.731 rs7983602 chr13:113620482 A/G cg08528486 chr13:113648767 MCF2L -0.38 -5.77 -0.3 1.79e-8 Systolic blood pressure; LIHC cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg27572855 chr1:25598939 RHD 0.4 8.67 0.42 1.81e-16 Erythrocyte sedimentation rate; LIHC cis rs7044106 0.664 rs7861679 chr9:123375589 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.67 -10.44 -0.49 2.46e-22 Hip circumference adjusted for BMI; LIHC cis rs116248771 0.690 rs116470672 chr3:158337762 C/T cg16708174 chr3:158430962 RARRES1 0.47 6.28 0.32 1.04e-9 diarrhoeal disease at age 2; LIHC cis rs2153535 0.580 rs1932281 chr6:8473765 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs826838 1.000 rs1719848 chr12:39085586 A/G cg13010199 chr12:38710504 ALG10B -0.4 -6.0 -0.31 5.11e-9 Heart rate; LIHC trans rs2727020 0.636 rs10839275 chr11:49438962 T/A cg18944383 chr4:111397179 ENPEP 0.25 6.2 0.32 1.66e-9 Coronary artery disease; LIHC cis rs11785400 1.000 rs6995314 chr8:143749718 A/G cg24634471 chr8:143751801 JRK -0.52 -8.37 -0.41 1.54e-15 Schizophrenia; LIHC cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg07424592 chr7:64974309 NA 0.79 8.55 0.42 4.11e-16 Diabetic kidney disease; LIHC cis rs11971779 0.648 rs10230407 chr7:139103893 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.09 0.48 3.87e-21 Diisocyanate-induced asthma; LIHC cis rs9503598 0.644 rs10498663 chr6:3430439 C/T cg00476032 chr6:3446245 SLC22A23 -0.35 -6.56 -0.33 2.05e-10 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg00750074 chr16:89608354 SPG7 -0.46 -7.5 -0.38 5.6e-13 Multiple myeloma (IgH translocation); LIHC cis rs2346177 0.554 rs34854267 chr2:46708542 T/C cg02822958 chr2:46747628 ATP6V1E2 0.52 7.86 0.39 5.11e-14 HDL cholesterol; LIHC cis rs9658691 0.607 rs12415680 chr10:90780737 A/T cg03111039 chr10:90751583 FAS;ACTA2 -0.93 -6.71 -0.34 8.01e-11 Mosquito bite size; LIHC cis rs12908161 0.683 rs12903256 chr15:85308141 G/T cg03959625 chr15:84868606 LOC388152 0.38 5.84 0.3 1.24e-8 Schizophrenia; LIHC cis rs4907240 0.961 rs60959055 chr2:97313450 C/G cg26665480 chr2:98280029 ACTR1B -0.4 -5.95 -0.31 6.82e-9 Event-related brain oscillations; LIHC cis rs7107174 1.000 rs11601196 chr11:78043431 A/C cg02023728 chr11:77925099 USP35 0.49 9.18 0.44 4.19e-18 Testicular germ cell tumor; LIHC cis rs3806843 0.900 rs2563280 chr5:140131530 G/C cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7677751 0.806 rs17084051 chr4:55087581 C/A cg17187183 chr4:55093834 PDGFRA 0.66 8.31 0.41 2.35e-15 Corneal astigmatism; LIHC cis rs9640161 0.750 rs73170185 chr7:150030191 C/A cg27494647 chr7:150038898 RARRES2 0.33 5.95 0.31 6.68e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg14671364 chr1:107599128 PRMT6 0.49 7.29 0.37 2.19e-12 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7312774 0.529 rs12314792 chr12:107333672 T/C cg16260113 chr12:107380972 MTERFD3 0.85 10.88 0.51 7.23e-24 Severe influenza A (H1N1) infection; LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg23131131 chr22:24373011 LOC391322 -0.7 -10.21 -0.48 1.59e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs637571 0.544 rs55704213 chr11:65730002 C/A cg17712092 chr4:129076599 LARP1B 0.75 13.27 0.58 1.08e-32 Eosinophil percentage of white cells; LIHC cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 8.78 0.43 8.07e-17 Platelet count; LIHC cis rs72634258 0.945 rs12757968 chr1:8106201 A/G cg00042356 chr1:8021962 PARK7 0.9 8.79 0.43 7.65e-17 Inflammatory bowel disease; LIHC cis rs1670533 1.000 rs6852850 chr4:1052857 C/G cg27284194 chr4:1044797 NA 0.6 8.93 0.43 2.6e-17 Recombination rate (females); LIHC cis rs1008375 0.863 rs4698632 chr4:17614894 T/C cg02297831 chr4:17616191 MED28 0.45 7.1 0.36 7.21e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7927771 0.524 rs10838777 chr11:47860954 A/C cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC cis rs12893668 0.608 rs12889721 chr14:104034863 C/T cg19000871 chr14:103996768 TRMT61A -0.38 -6.26 -0.32 1.15e-9 Reticulocyte count; LIHC cis rs7980687 0.662 rs585522 chr12:123550813 A/G cg00376283 chr12:123451042 ABCB9 0.63 8.82 0.43 5.8e-17 Height;Educational attainment;Head circumference (infant); LIHC cis rs4234798 1.000 rs4234798 chr4:7219933 G/T cg12632249 chr4:7449638 SORCS2 0.29 5.73 0.3 2.17e-8 Insulin-like growth factors; LIHC cis rs5753618 0.561 rs4820963 chr22:31698166 C/T cg22777020 chr22:31556080 RNF185 -0.55 -6.35 -0.32 6.77e-10 Colorectal cancer; LIHC cis rs2074193 0.951 rs215344 chr12:47733024 A/G cg02516419 chr12:47771422 NA -0.42 -5.82 -0.3 1.38e-8 Migraine with aura; LIHC cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg08888203 chr3:10149979 C3orf24 0.53 6.42 0.33 4.61e-10 Alzheimer's disease; LIHC cis rs782590 0.537 rs12619903 chr2:55884106 T/A cg18811423 chr2:55921094 PNPT1 -0.53 -7.59 -0.38 2.98e-13 Metabolic syndrome; LIHC cis rs5769765 0.740 rs138838 chr22:50180951 C/G cg02269571 chr22:50332266 NA -0.75 -6.95 -0.35 1.85e-11 Schizophrenia; LIHC cis rs2072499 0.750 rs7534339 chr1:156156219 A/G cg24450063 chr1:156163899 SLC25A44 0.75 7.97 0.4 2.43e-14 Testicular germ cell tumor; LIHC cis rs7927592 0.913 rs7107622 chr11:68374183 T/C cg16797656 chr11:68205561 LRP5 0.5 7.78 0.39 8.81e-14 Total body bone mineral density; LIHC cis rs12478296 1.000 rs55717005 chr2:243041071 T/A cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.1e-27 Obesity-related traits; LIHC cis rs769267 0.930 rs4808967 chr19:19640524 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.77 0.3 1.75e-8 Tonsillectomy; LIHC cis rs9328573 1.000 rs9920711 chr15:100510478 T/C cg09918751 chr15:100517450 ADAMTS17 -0.5 -7.7 -0.38 1.48e-13 Urate levels in lean individuals; LIHC cis rs7512552 0.525 rs2298161 chr1:150237624 A/G cg15654264 chr1:150340011 RPRD2 0.49 8.15 0.4 6.82e-15 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs7927592 0.763 rs11822059 chr11:68300822 T/G cg16797656 chr11:68205561 LRP5 0.5 8.83 0.43 5.57e-17 Total body bone mineral density; LIHC cis rs929354 0.742 rs886677 chr7:157003782 T/A cg16102536 chr7:156981717 UBE3C 0.35 5.87 0.3 1.02e-8 Body mass index; LIHC cis rs1113500 0.933 rs11185260 chr1:108635079 A/T cg06207961 chr1:108661230 NA -0.39 -7.76 -0.39 1.01e-13 Growth-regulated protein alpha levels; LIHC cis rs798554 0.679 rs2533868 chr7:2886559 G/A cg04166393 chr7:2884313 GNA12 0.51 8.27 0.41 3.1e-15 Height; LIHC cis rs796364 1.000 rs281794 chr2:200846666 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.77 9.18 0.44 4.25e-18 Schizophrenia; LIHC cis rs7208859 0.623 rs79607958 chr17:28934548 T/G cg14067834 chr17:29058358 SUZ12P 0.66 6.45 0.33 3.75e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6547741 0.967 rs4665996 chr2:27814343 T/C cg27432699 chr2:27873401 GPN1 0.72 11.61 0.53 1.73e-26 Oral cavity cancer; LIHC cis rs9534288 0.797 rs7998854 chr13:46592174 C/A cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs250677 0.687 rs40523 chr5:148444186 A/T cg12140854 chr5:148520817 ABLIM3 0.45 6.08 0.31 3.19e-9 Breast cancer; LIHC cis rs6690583 0.623 rs893620 chr1:85425821 T/C cg22153463 chr1:85462885 MCOLN2 0.49 5.78 0.3 1.72e-8 Serum sulfate level; LIHC cis rs1461503 0.932 rs10892934 chr11:122837950 C/T cg14473756 chr11:122847823 NA -0.37 -6.65 -0.34 1.18e-10 Menarche (age at onset); LIHC cis rs13108904 0.901 rs12641735 chr4:1304434 G/C cg16405210 chr4:1374714 KIAA1530 -0.54 -8.2 -0.41 4.97e-15 Obesity-related traits; LIHC cis rs9486719 1.000 rs11152959 chr6:96900272 C/T cg06623918 chr6:96969491 KIAA0776 -0.72 -7.12 -0.36 6.31e-12 Migraine;Coronary artery disease; LIHC cis rs1185460 0.967 rs1784460 chr11:118938371 A/T cg23280166 chr11:118938394 VPS11 -0.6 -8.36 -0.41 1.56e-15 Coronary artery disease; LIHC cis rs6430585 0.591 rs309170 chr2:136672775 C/T cg07169764 chr2:136633963 MCM6 0.97 14.86 0.63 6.81e-39 Corneal structure; LIHC cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg19318889 chr4:1322082 MAEA 0.44 5.95 0.31 6.61e-9 Obesity-related traits; LIHC cis rs7772486 0.790 rs6926657 chr6:146255794 G/A cg23711669 chr6:146136114 FBXO30 -0.63 -10.85 -0.51 9.06e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs35110281 1.000 rs35110281 chr21:45068947 T/A cg04455712 chr21:45112962 RRP1B 0.45 7.6 0.38 2.81e-13 Mean corpuscular volume; LIHC cis rs3818285 0.556 rs3758409 chr10:111669239 A/C cg00817464 chr10:111662876 XPNPEP1 -0.5 -7.7 -0.38 1.47e-13 Superior crus of antihelix expression; LIHC cis rs7917772 0.508 rs2252147 chr10:104467774 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.59 7.1 0.36 7.04e-12 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs317689 0.658 rs479971 chr12:69672471 A/G cg14784868 chr12:69753453 YEATS4 0.55 7.85 0.39 5.51e-14 Response to diuretic therapy; LIHC cis rs2228479 0.850 rs11649162 chr16:89807131 C/A cg19635926 chr16:89946313 TCF25 0.49 6.21 0.32 1.5e-9 Skin colour saturation; LIHC cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg12373951 chr3:133503437 NA -0.69 -12.32 -0.55 3.98e-29 Iron status biomarkers; LIHC cis rs10089 0.953 rs7713860 chr5:127428789 G/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.86 0.35 3.28e-11 Ileal carcinoids; LIHC cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg11301795 chr4:187892539 NA -0.27 -7.1 -0.36 7.23e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs35306767 0.622 rs66462130 chr10:1022108 C/T cg20503657 chr10:835505 NA 0.86 7.71 0.38 1.36e-13 Eosinophil percentage of granulocytes; LIHC cis rs875971 0.545 rs2173571 chr7:65770379 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.24 0.36 3.03e-12 Aortic root size; LIHC cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.49e-11 Diabetic kidney disease; LIHC cis rs1707322 0.721 rs10430124 chr1:46221617 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.43 0.37 8.59e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs769267 0.965 rs2023882 chr19:19405405 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.6 9.48 0.46 4.3e-19 Tonsillectomy; LIHC cis rs1552244 0.554 rs3846167 chr3:9996426 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -8.03 -0.4 1.59e-14 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08347471 chr19:36297670 PRODH2 0.43 6.95 0.35 1.85e-11 Pancreatic cancer; LIHC cis rs240110 0.515 rs12530388 chr6:101329173 A/C cg09795085 chr6:101329169 ASCC3 0.58 8.05 0.4 1.39e-14 Neuroticism; LIHC cis rs79149102 0.579 rs58294763 chr15:75299768 G/A cg16226627 chr15:75307476 SCAMP5 0.54 9.6 0.46 1.7e-19 Lung cancer; LIHC cis rs1395 0.778 rs60631624 chr2:27497815 T/G cg22903471 chr2:27725779 GCKR -0.43 -6.08 -0.31 3.22e-9 Blood metabolite levels; LIHC cis rs6456156 0.846 rs7774396 chr6:167519786 G/A cg07741184 chr6:167504864 NA 0.26 6.36 0.33 6.45e-10 Primary biliary cholangitis; LIHC cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC cis rs10078 0.848 rs890985 chr5:479746 C/G cg07599136 chr5:415885 AHRR 0.58 9.49 0.46 4.23e-19 Fat distribution (HIV); LIHC cis rs2073300 0.609 rs56094936 chr20:23401586 G/A cg16736954 chr20:23401023 NAPB 0.71 8.34 0.41 1.82e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3753275 0.568 rs1812457 chr1:8685520 C/T cg20416874 chr1:8611966 RERE -0.52 -6.38 -0.33 5.64e-10 Educational attainment; LIHC cis rs7772486 0.790 rs2814879 chr6:146201743 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.93 0.31 7.39e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4423214 1.000 rs4423214 chr11:71173254 C/T cg05163923 chr11:71159392 DHCR7 0.87 13.22 0.58 1.58e-32 Vitamin D levels; LIHC trans rs1005277 0.579 rs2504143 chr10:38383706 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 5.86e-12 Diabetic kidney disease; LIHC cis rs8177179 0.967 rs6782434 chr3:133438834 C/G cg18769074 chr3:133464867 TF 0.27 5.98 0.31 5.56e-9 Iron status biomarkers (transferrin levels); LIHC cis rs600806 0.821 rs3879448 chr1:109891423 C/G cg08911820 chr1:110026001 ATXN7L2 -0.52 -6.73 -0.34 7.23e-11 Intelligence (multi-trait analysis); LIHC cis rs3981351 0.624 rs12415607 chr10:115438204 A/C cg24846397 chr10:115438155 CASP7 0.43 6.67 0.34 1.06e-10 Obesity-related traits; LIHC cis rs11711311 1.000 rs12636577 chr3:113497507 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.17 0.44 4.42e-18 IgG glycosylation; LIHC cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.14 -17.38 -0.68 6.12e-49 Gut microbiome composition (summer); LIHC cis rs7937682 0.737 rs542275 chr11:111431614 C/T cg09085632 chr11:111637200 PPP2R1B -0.76 -9.61 -0.46 1.67e-19 Primary sclerosing cholangitis; LIHC cis rs8062405 0.755 rs7193402 chr16:28586127 A/G cg16576597 chr16:28551801 NUPR1 0.47 7.26 0.37 2.7e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs459571 0.920 rs455073 chr9:136909141 G/C cg13789015 chr9:136890014 NCRNA00094 0.46 8.33 0.41 2.01e-15 Platelet distribution width; LIHC cis rs6061231 0.724 rs1570027 chr20:60968596 A/G cg06026331 chr20:60912101 LAMA5 0.49 6.47 0.33 3.43e-10 Colorectal cancer; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs6076065 0.630 rs2424559 chr20:23430519 A/G cg11657817 chr20:23433608 CST11 0.32 7.59 0.38 3.04e-13 Facial morphology (factor 15, philtrum width); LIHC cis rs60871478 0.898 rs62432897 chr7:825429 A/G cg05535760 chr7:792225 HEATR2 0.93 12.83 0.57 4.98e-31 Cerebrospinal P-tau181p levels; LIHC cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.53 0.56 6.98e-30 Alzheimer's disease; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg14835113 chr13:111303423 CARS2 0.51 6.33 0.32 7.49e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg11502198 chr6:26597334 ABT1 0.64 9.97 0.47 9.9e-21 Intelligence (multi-trait analysis); LIHC cis rs9733 0.596 rs12077833 chr1:150674333 C/T cg18016565 chr1:150552671 MCL1 0.58 11.5 0.53 4.36e-26 Tonsillectomy; LIHC cis rs9818758 0.556 rs9835439 chr3:49220330 G/C cg07636037 chr3:49044803 WDR6 -0.83 -8.47 -0.42 7.51e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.63 0.62 5.66e-38 Prudent dietary pattern; LIHC cis rs2070488 0.965 rs7642472 chr3:38525567 T/C cg24069376 chr3:38537580 EXOG 0.43 8.0 0.4 1.98e-14 Electrocardiographic conduction measures; LIHC cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.68 -0.5 3.48e-23 Alzheimer's disease; LIHC cis rs9814567 1.000 rs6772896 chr3:134203347 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.73 -0.3 2.21e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs34779708 0.931 rs12767414 chr10:35390193 C/T cg03585969 chr10:35415529 CREM 0.8 11.88 0.54 1.7e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2050392 0.931 rs2265187 chr10:30690844 C/T cg25182066 chr10:30743637 MAP3K8 -0.44 -7.18 -0.36 4.26e-12 Inflammatory bowel disease; LIHC cis rs929354 0.742 rs886677 chr7:157003782 T/A cg17757837 chr7:157058334 UBE3C 0.74 12.1 0.55 2.67e-28 Body mass index; LIHC cis rs3857067 0.806 rs7669168 chr4:95104881 G/T cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.79 -0.39 8.19e-14 QT interval; LIHC cis rs77106637 1.000 rs3862791 chr11:72501002 C/T cg03713592 chr11:72463424 ARAP1 0.93 8.51 0.42 5.35e-16 Type 2 diabetes; LIHC cis rs4555082 0.915 rs79048296 chr14:105754944 G/A cg06808227 chr14:105710500 BRF1 -0.54 -7.06 -0.36 9.42e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs2242116 0.896 rs724449 chr3:46935681 C/T cg23352942 chr3:46931381 PTH1R -0.33 -8.84 -0.43 4.97e-17 Birth weight; LIHC trans rs61931739 0.500 rs11053280 chr12:34559297 G/T cg26384229 chr12:38710491 ALG10B 0.79 9.68 0.46 9.64e-20 Morning vs. evening chronotype; LIHC cis rs6582630 0.519 rs8189561 chr12:38296178 G/A cg26384229 chr12:38710491 ALG10B 0.59 8.15 0.4 7e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs57590327 0.679 rs35754586 chr3:81601765 T/C cg07356753 chr3:81810745 GBE1 -0.47 -6.5 -0.33 2.93e-10 Extraversion; LIHC cis rs644799 0.504 rs523049 chr11:95594831 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.6 8.55 0.42 4.29e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6964587 1.000 rs12704635 chr7:91737324 T/G cg17063962 chr7:91808500 NA 1.02 19.59 0.73 8.04e-58 Breast cancer; LIHC cis rs600806 0.850 rs1880670 chr1:109941133 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg09904177 chr6:26538194 HMGN4 0.57 11.21 0.52 4.9e-25 Intelligence (multi-trait analysis); LIHC trans rs3942852 0.774 rs1039481 chr11:48182237 G/A cg03929089 chr4:120376271 NA -0.56 -7.62 -0.38 2.6e-13 Acute lymphoblastic leukemia (childhood); LIHC trans rs11088226 0.681 rs1134747 chr21:33939011 T/A cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.06e-34 Gastritis; LIHC trans rs7618501 1.000 rs7618501 chr3:49772647 A/G cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC cis rs875971 0.508 rs10950045 chr7:66066373 T/C cg14393609 chr7:65229607 NA -0.35 -5.78 -0.3 1.72e-8 Aortic root size; LIHC cis rs250677 0.687 rs171636 chr5:148434545 G/A cg18129178 chr5:148520854 ABLIM3 -0.55 -7.1 -0.36 7.14e-12 Breast cancer; LIHC cis rs8067354 0.872 rs2645488 chr17:57889405 T/G cg13753209 chr17:57696993 CLTC 0.59 9.03 0.44 1.28e-17 Hemoglobin concentration; LIHC cis rs3770081 1.000 rs12624126 chr2:86342366 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -7.9 -0.39 3.9e-14 Facial emotion recognition (sad faces); LIHC cis rs208520 0.690 rs207096 chr6:66797287 T/C cg07460842 chr6:66804631 NA -0.84 -9.29 -0.45 1.86e-18 Exhaled nitric oxide output; LIHC cis rs17310467 0.541 rs78522696 chr20:33182159 G/C cg08999081 chr20:33150536 PIGU 0.59 6.13 0.31 2.42e-9 Hemostatic factors and hematological phenotypes; LIHC trans rs11039798 0.588 rs11039855 chr11:48610091 A/G cg15704280 chr7:45808275 SEPT13 0.57 6.34 0.32 7.24e-10 Axial length; LIHC cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 -0.41 -5.83 -0.3 1.26e-8 Schizophrenia; LIHC cis rs2574704 0.886 rs7614263 chr3:11650269 T/C cg15876825 chr3:11651881 VGLL4 -0.5 -8.2 -0.41 4.88e-15 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26164735 chr4:71768712 MOBKL1A 0.42 6.11 0.31 2.76e-9 Pancreatic cancer; LIHC cis rs8141529 0.702 rs469992 chr22:29314899 T/C cg15103426 chr22:29168792 CCDC117 -0.57 -9.15 -0.44 5.25e-18 Lymphocyte counts; LIHC cis rs933688 0.502 rs4916858 chr5:90601290 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 -0.38 -6.04 -0.31 3.98e-9 Smoking behavior; LIHC cis rs2997447 0.761 rs17184884 chr1:26446565 G/A cg19633962 chr1:26362018 EXTL1 -0.64 -5.88 -0.3 9.64e-9 QRS complex (12-leadsum); LIHC cis rs17060993 0.618 rs17056484 chr8:26848328 C/T cg22544144 chr8:26435318 DPYSL2 0.66 5.96 0.31 6.17e-9 Musician's dystonia; LIHC cis rs7124681 0.584 rs1471712 chr11:47912150 G/A cg20307385 chr11:47447363 PSMC3 -0.69 -10.28 -0.49 8.75e-22 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg10360323 chr17:41437877 NA 0.41 6.04 0.31 4.09e-9 Menopause (age at onset); LIHC cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg11062466 chr8:58055876 NA 0.47 6.6 0.34 1.59e-10 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.45 6.41 0.33 4.82e-10 Schizophrenia; LIHC cis rs2404602 0.647 rs11072607 chr15:76908529 C/T cg03037974 chr15:76606532 NA -0.61 -10.2 -0.48 1.7e-21 Blood metabolite levels; LIHC cis rs7551222 0.646 rs4951382 chr1:204451495 T/C cg20240347 chr1:204465584 NA -0.32 -6.7 -0.34 8.54e-11 Schizophrenia; LIHC cis rs6089584 1.000 rs6089581 chr20:60562394 G/A cg06108461 chr20:60628389 TAF4 -0.88 -13.71 -0.6 2.16e-34 Body mass index; LIHC trans rs2727020 0.556 rs2866365 chr11:49390731 A/G cg18944383 chr4:111397179 ENPEP 0.33 7.48 0.37 6.44e-13 Coronary artery disease; LIHC cis rs12477438 0.765 rs7607578 chr2:99669771 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs2070488 1.000 rs7373805 chr3:38455439 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.66 0.65 4.59e-42 Electrocardiographic conduction measures; LIHC cis rs2439831 0.702 rs2788 chr15:44064886 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.5 0.42 6.09e-16 Lung cancer in ever smokers; LIHC cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg05368731 chr17:41323189 NBR1 0.72 12.06 0.55 3.69e-28 Menopause (age at onset); LIHC cis rs10088262 0.591 rs13270541 chr8:124794849 G/A cg20713898 chr8:124780851 FAM91A1 -0.55 -7.33 -0.37 1.63e-12 Pancreatic cancer; LIHC cis rs60871478 0.838 rs7789321 chr7:800977 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.54 6.34 0.32 7.44e-10 Cerebrospinal P-tau181p levels; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg06873352 chr17:61820015 STRADA 0.72 12.83 0.57 4.79e-31 Prudent dietary pattern; LIHC cis rs3112357 1.000 rs3112357 chr7:135396896 A/G cg20392616 chr7:135392013 SLC13A4 0.41 6.79 0.34 5.12e-11 Plantar warts; LIHC cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg02951883 chr7:2050386 MAD1L1 -0.72 -11.96 -0.54 8.63e-28 Schizophrenia; LIHC cis rs903552 1.000 rs11634912 chr15:102005510 A/G cg00659931 chr15:102010125 PCSK6 -0.46 -6.19 -0.32 1.7e-9 Diabetic kidney disease; LIHC cis rs1005277 0.540 rs7903942 chr10:37929276 C/T cg25427524 chr10:38739819 LOC399744 0.63 11.98 0.54 7.74e-28 Extrinsic epigenetic age acceleration; LIHC cis rs11585357 0.895 rs112208664 chr1:17632010 G/A cg08277548 chr1:17600880 PADI3 -0.58 -6.22 -0.32 1.46e-9 Hair shape; LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg09455208 chr3:40491958 NA -0.4 -8.03 -0.4 1.54e-14 Renal cell carcinoma; LIHC cis rs17539620 0.534 rs6557363 chr6:154827813 A/G cg17771515 chr6:154831774 CNKSR3 0.53 5.86 0.3 1.09e-8 Lipoprotein (a) levels; LIHC cis rs3540 0.538 rs2074585 chr15:91009484 G/A cg22089800 chr15:90895588 ZNF774 0.5 6.52 0.33 2.51e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs4919694 0.536 rs12256506 chr10:104963618 T/A cg04362960 chr10:104952993 NT5C2 0.85 7.04 0.36 1.05e-11 Arsenic metabolism; LIHC cis rs10197940 0.662 rs4335940 chr2:152275304 A/G cg19508488 chr2:152266495 RIF1 -0.57 -8.14 -0.4 7.57e-15 Lung cancer; LIHC cis rs910316 0.904 rs7156089 chr14:75645527 A/G cg08847533 chr14:75593920 NEK9 -0.88 -18.38 -0.7 5.83e-53 Height; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg06420487 chr17:61919686 SMARCD2 0.44 6.14 0.32 2.26e-9 Height; LIHC cis rs4820294 1.000 rs62236667 chr22:38061520 C/G cg10587741 chr22:38071170 LGALS1 0.73 12.8 0.57 6.38e-31 Fat distribution (HIV); LIHC cis rs4759375 1.000 rs10773004 chr12:123788758 G/A cg00376283 chr12:123451042 ABCB9 -0.5 -6.4 -0.33 5.02e-10 HDL cholesterol; LIHC cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg16405210 chr4:1374714 KIAA1530 -0.45 -6.93 -0.35 2.04e-11 Obesity-related traits; LIHC cis rs3768617 0.811 rs10911200 chr1:182998377 T/C ch.1.3577855R chr1:183094577 LAMC1 0.5 7.88 0.39 4.38e-14 Fuchs's corneal dystrophy; LIHC cis rs11662586 1.000 rs8093291 chr18:77701294 G/A cg20368463 chr18:77673604 PQLC1 0.41 6.24 0.32 1.29e-9 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs116095464 0.558 rs1971229 chr5:268187 A/G cg22857025 chr5:266934 NA -1.51 -18.77 -0.71 1.57e-54 Breast cancer; LIHC cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg11644478 chr21:40555479 PSMG1 0.8 10.12 0.48 3.19e-21 Cognitive function; LIHC cis rs2806561 0.765 rs1997866 chr1:23512524 A/G cg12483005 chr1:23474871 LUZP1 0.45 7.16 0.36 5.1e-12 Height; LIHC cis rs892961 0.932 rs7208671 chr17:75413129 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs9818758 0.607 rs34343820 chr3:49309534 C/G cg00383909 chr3:49044727 WDR6 0.77 6.32 0.32 8.14e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs769267 0.895 rs2916074 chr19:19530270 C/T cg15052019 chr19:19431593 KIAA0892;SF4 0.42 5.86 0.3 1.1e-8 Tonsillectomy; LIHC cis rs7312933 0.669 rs7974476 chr12:42542484 C/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 8.1 0.4 9.5e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs3099143 1.000 rs7178759 chr15:77143513 A/G cg21673338 chr15:77095150 SCAPER 0.44 7.39 0.37 1.16e-12 Recalcitrant atopic dermatitis; LIHC cis rs2576037 0.523 rs4890705 chr18:44509758 A/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.1 -0.36 7.26e-12 Personality dimensions; LIHC cis rs7707921 1.000 rs1543911 chr5:81504841 C/T cg15871215 chr5:81402204 ATG10 0.59 5.82 0.3 1.38e-8 Breast cancer; LIHC cis rs174601 0.833 rs174541 chr11:61565908 T/C cg07689907 chr11:61582574 FADS1 0.39 5.83 0.3 1.27e-8 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC trans rs993804 0.527 rs7630907 chr3:25122044 G/C cg25259296 chr21:43235862 PRDM15 -0.41 -6.03 -0.31 4.15e-9 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs2070488 0.965 rs2366119 chr3:38484453 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.94 0.65 3.74e-43 Electrocardiographic conduction measures; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg10553204 chr2:20871195 GDF7 -0.41 -7.52 -0.38 4.88e-13 Abdominal aortic aneurysm; LIHC cis rs644799 0.623 rs17207890 chr11:95490754 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.84 13.88 0.6 4.62e-35 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg06481639 chr22:41940642 POLR3H 0.7 6.85 0.35 3.35e-11 Vitiligo; LIHC cis rs60871478 0.786 rs62432898 chr7:826102 G/A cg05535760 chr7:792225 HEATR2 0.97 13.44 0.59 2.33e-33 Cerebrospinal P-tau181p levels; LIHC cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg12042659 chr19:58951599 ZNF132 0.38 6.33 0.32 7.59e-10 Uric acid clearance; LIHC cis rs12477438 0.798 rs13414153 chr2:99624748 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.48 -0.49 1.81e-22 Chronic sinus infection; LIHC cis rs1707322 1.000 rs785465 chr1:46522577 G/T cg06784218 chr1:46089804 CCDC17 0.36 6.46 0.33 3.55e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 0.549 rs60249586 chr3:40246659 G/A cg00656387 chr3:40428638 ENTPD3 0.4 6.29 0.32 9.71e-10 Renal cell carcinoma; LIHC trans rs11088226 0.681 rs4547609 chr21:33953542 G/A cg09050820 chr6:167586206 TCP10L2 0.89 15.1 0.63 7.73e-40 Gastritis; LIHC cis rs700651 0.624 rs12105927 chr2:198937258 G/A cg10820045 chr2:198174542 NA 0.41 6.03 0.31 4.23e-9 Intracranial aneurysm; LIHC cis rs1153858 1.000 rs1554521 chr15:45664189 A/T cg14582100 chr15:45693742 SPATA5L1 -0.33 -6.38 -0.33 5.6e-10 Homoarginine levels; LIHC cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.27e-12 Bipolar disorder; LIHC cis rs1580019 0.562 rs4720064 chr7:32559638 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 26.45 0.82 1.05e-84 Cognitive ability; LIHC cis rs7192750 0.586 rs8054111 chr16:71990651 A/G cg06353428 chr16:71660113 MARVELD3 0.76 8.79 0.43 7.19e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs2742417 0.603 rs2673075 chr3:45778288 C/A cg04837898 chr3:45731254 SACM1L -0.51 -8.62 -0.42 2.56e-16 Response to anti-depressant treatment in major depressive disorder; LIHC trans rs916888 0.821 rs199509 chr17:44858728 G/A cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11190604 0.943 rs113791644 chr10:102324330 T/G cg07080220 chr10:102295463 HIF1AN 0.52 6.84 0.35 3.67e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs67981189 0.593 rs10145824 chr14:71447732 T/C cg15816911 chr14:71606274 NA 0.41 6.63 0.34 1.33e-10 Schizophrenia; LIHC cis rs875971 1.000 rs778722 chr7:65844828 T/C cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs11644362 1.000 rs35325771 chr16:12985138 A/C cg06890432 chr16:12997467 SHISA9 -0.4 -6.73 -0.34 6.96e-11 Positive affect;Subjective well-being; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23274123 chr1:229478617 C1orf96 -0.46 -6.82 -0.35 4.25e-11 Cognitive function; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06528150 chr2:61293470 KIAA1841 0.42 6.04 0.31 3.98e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8067545 0.611 rs12942568 chr17:20117893 G/T cg13482628 chr17:19912719 NA -0.42 -6.83 -0.35 3.8e-11 Schizophrenia; LIHC cis rs6121246 0.567 rs6058203 chr20:30198979 C/T cg13852791 chr20:30311386 BCL2L1 0.76 6.82 0.35 4.02e-11 Mean corpuscular hemoglobin; LIHC cis rs5753618 0.539 rs1034588 chr22:31616301 A/G cg07713946 chr22:31675144 LIMK2 -0.42 -7.4 -0.37 1.04e-12 Colorectal cancer; LIHC cis rs2412488 1.000 rs10017903 chr4:54267009 C/T cg22241045 chr4:54363911 LNX1 -0.47 -7.51 -0.38 5.16e-13 DNA methylation (variation); LIHC cis rs35306767 0.855 rs61830932 chr10:934183 T/C cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs2637030 0.559 rs6881928 chr5:52988609 C/A cg06476337 chr5:52856530 NDUFS4 0.42 6.77 0.34 5.57e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs4727027 0.835 rs6959224 chr7:148784495 A/G cg23583168 chr7:148888333 NA -0.63 -8.87 -0.43 4.19e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6964587 1.000 rs12536529 chr7:91684086 C/T cg17063962 chr7:91808500 NA -1.02 -19.56 -0.73 1.01e-57 Breast cancer; LIHC cis rs3008870 0.755 rs2815355 chr1:67485034 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.64 10.68 0.5 3.73e-23 Lymphocyte percentage of white cells; LIHC cis rs7534824 0.556 rs61780323 chr1:101433407 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 6.85 0.35 3.43e-11 Refractive astigmatism; LIHC cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg13393036 chr8:95962371 TP53INP1 -0.39 -8.81 -0.43 6.55e-17 Type 2 diabetes; LIHC cis rs2180341 1.000 rs6569480 chr6:127621748 A/G cg27446573 chr6:127587934 RNF146 1.05 16.04 0.66 1.41e-43 Breast cancer; LIHC cis rs7395581 0.959 rs35879051 chr11:47275882 C/G cg25783544 chr11:47291846 MADD 0.45 6.66 0.34 1.06e-10 HDL cholesterol; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg21970626 chr13:21893289 NA -0.41 -7.02 -0.36 1.18e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9733 0.519 rs3768005 chr1:150680988 A/T cg18016565 chr1:150552671 MCL1 0.59 11.39 0.52 1.06e-25 Tonsillectomy; LIHC cis rs6089829 0.925 rs6122086 chr20:61664528 T/C cg08564027 chr20:61660810 NA 0.4 7.65 0.38 2.13e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs6665290 0.935 rs1929862 chr1:227199718 G/A cg10327440 chr1:227177885 CDC42BPA -1.21 -30.49 -0.85 1.55e-99 Myeloid white cell count; LIHC cis rs11676348 0.755 rs6436026 chr2:218951738 T/A cg20019365 chr2:219134978 PNKD;AAMP -0.42 -5.74 -0.3 2.06e-8 Ulcerative colitis; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs7187994 0.806 rs12445172 chr16:84747016 C/G cg07647771 chr16:84786436 USP10 -0.32 -6.14 -0.31 2.33e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg11644478 chr21:40555479 PSMG1 -0.76 -9.54 -0.46 2.85e-19 Cognitive function; LIHC cis rs6728642 0.803 rs11891458 chr2:97632450 G/T cg26665480 chr2:98280029 ACTR1B -0.58 -6.44 -0.33 3.96e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs875971 0.964 rs2161065 chr7:65932905 A/G cg11764359 chr7:65958608 NA 0.88 15.8 0.65 1.25e-42 Aortic root size; LIHC cis rs919433 0.680 rs2565163 chr2:198354414 T/C cg03934865 chr2:198174659 NA 0.54 8.3 0.41 2.46e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9534288 0.843 rs4362286 chr13:46566514 G/A cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs59901009 0.569 rs12280005 chr11:10228452 G/A cg01453529 chr11:10209919 SBF2 -0.43 -7.87 -0.39 4.77e-14 Hematocrit;Hemoglobin concentration; LIHC cis rs708547 0.599 rs2948348 chr4:57848772 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.69 12.36 0.56 2.79e-29 Response to bleomycin (chromatid breaks); LIHC cis rs2404602 0.647 rs11633869 chr15:77133322 G/T cg23625390 chr15:77176239 SCAPER 0.55 9.26 0.45 2.36e-18 Blood metabolite levels; LIHC cis rs7635838 0.687 rs7625495 chr3:11377918 G/T cg00170343 chr3:11313890 ATG7 0.6 10.03 0.48 6.14e-21 HDL cholesterol; LIHC cis rs2816062 1.000 rs2816062 chr1:18903902 G/A cg18795169 chr1:18902165 NA -0.73 -15.08 -0.63 9.44e-40 Urate levels in lean individuals; LIHC cis rs6952808 0.691 rs2398709 chr7:2112548 C/T cg02951883 chr7:2050386 MAD1L1 -0.65 -10.56 -0.5 9.37e-23 Bipolar disorder and schizophrenia; LIHC cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg23758822 chr17:41437982 NA 0.94 18.01 0.7 1.79e-51 Menopause (age at onset); LIHC cis rs9902453 0.689 rs7216948 chr17:28203173 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.82 14.01 0.6 1.53e-35 Coffee consumption (cups per day); LIHC cis rs17376456 0.825 rs28534784 chr5:93063332 C/A cg25358565 chr5:93447407 FAM172A 1.04 9.47 0.46 4.9e-19 Diabetic retinopathy; LIHC cis rs926392 0.932 rs6513589 chr20:37686585 A/G cg16355469 chr20:37678765 NA 0.37 5.9 0.3 8.89e-9 Dialysis-related mortality; LIHC cis rs4631830 0.540 rs2843562 chr10:51496796 A/G cg20129853 chr10:51489980 NA 0.38 8.39 0.41 1.31e-15 Prostate-specific antigen levels; LIHC cis rs9611565 0.500 rs10775759 chr22:42088158 T/C cg03806693 chr22:41940476 POLR3H 0.83 9.52 0.46 3.24e-19 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18501264 chr19:33555827 RHPN2 -0.43 -6.54 -0.33 2.19e-10 Pancreatic cancer; LIHC cis rs709400 0.526 rs11622835 chr14:103967504 G/A cg26031613 chr14:104095156 KLC1 0.89 9.01 0.44 1.46e-17 Body mass index; LIHC cis rs7238033 0.663 rs17675121 chr18:43318185 T/C cg20610511 chr18:43302872 SLC14A1 0.4 6.77 0.34 5.65e-11 Bladder cancer; LIHC cis rs1451375 0.617 rs2329366 chr7:50544966 G/A cg14593290 chr7:50529359 DDC -0.62 -10.13 -0.48 2.9e-21 Malaria; LIHC cis rs116095464 0.558 rs7356535 chr5:284117 G/T cg22857025 chr5:266934 NA -1.52 -15.89 -0.65 5.89e-43 Breast cancer; LIHC cis rs11122272 0.735 rs722302 chr1:231480152 A/C cg06096015 chr1:231504339 EGLN1 0.5 9.14 0.44 5.69e-18 Hemoglobin concentration; LIHC cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.87 0.3 1.05e-8 Menopause (age at onset); LIHC cis rs920590 0.642 rs6993525 chr8:19671104 A/G cg17834443 chr8:19674713 INTS10 -0.49 -7.45 -0.37 7.6e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs9527 0.501 rs12244388 chr10:104640052 G/A cg04362960 chr10:104952993 NT5C2 0.4 5.85 0.3 1.15e-8 Arsenic metabolism; LIHC cis rs7309 0.810 rs11684253 chr2:162034536 G/T cg08807892 chr2:162101083 NA 0.45 7.64 0.38 2.25e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 7.33 0.37 1.63e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs929354 0.713 rs7798816 chr7:156940574 A/G cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg06873352 chr17:61820015 STRADA 0.74 13.03 0.58 8.81e-32 Prudent dietary pattern; LIHC cis rs796364 0.616 rs6718118 chr2:200691852 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.55 -6.18 -0.32 1.84e-9 Schizophrenia; LIHC trans rs561341 1.000 rs561341 chr17:30316385 T/G cg20587970 chr11:113659929 NA -1.38 -11.7 -0.53 8.09e-27 Hip circumference adjusted for BMI; LIHC trans rs11098499 0.913 rs11098496 chr4:120167466 C/G cg25214090 chr10:38739885 LOC399744 0.52 7.96 0.4 2.55e-14 Corneal astigmatism; LIHC cis rs2176862 1.000 rs73073734 chr3:46620518 T/C cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.3 -0.32 9.3e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs11758351 1.000 rs16891405 chr6:26204506 A/G cg01420254 chr6:26195488 NA 0.52 5.73 0.3 2.18e-8 Gout;Renal underexcretion gout; LIHC cis rs4808199 0.895 rs10419672 chr19:19471241 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.69 0.38 1.53e-13 Nonalcoholic fatty liver disease; LIHC cis rs2574704 0.683 rs6793495 chr3:11647942 G/A cg15876825 chr3:11651881 VGLL4 0.41 6.45 0.33 3.81e-10 Body mass index; LIHC cis rs2274273 0.744 rs8011808 chr14:55823344 A/T cg01864836 chr14:55583639 NA -0.4 -7.48 -0.38 6.13e-13 Protein biomarker; LIHC cis rs9918079 0.560 rs7438356 chr4:15624770 C/T cg24225360 chr4:15471699 CC2D2A -0.41 -6.69 -0.34 9.09e-11 Obesity-related traits; LIHC cis rs2072438 0.503 rs4837810 chr9:123881199 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.19 0.32 1.77e-9 Rheumatoid arthritis; LIHC cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.12 -0.36 6.31e-12 Diabetic kidney disease; LIHC cis rs7192750 0.562 rs9921412 chr16:71988106 C/T cg06353428 chr16:71660113 MARVELD3 0.77 8.89 0.43 3.46e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs6762 0.748 rs1130719 chr11:838760 T/A cg15787769 chr11:842744 TSPAN4;POLR2L -0.61 -7.43 -0.37 8.73e-13 Mean platelet volume; LIHC cis rs7408868 0.831 rs11672004 chr19:15277282 T/A cg02272795 chr19:15279244 NOTCH3 -0.31 -6.38 -0.33 5.67e-10 Pulse pressure; LIHC cis rs72653721 0.838 rs3756962 chr6:11006861 C/T cg13562911 chr6:11044106 ELOVL2 0.5 7.22 0.36 3.36e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs17685 0.753 rs10233282 chr7:75790081 C/T cg01364799 chr7:75623366 TMEM120A -0.52 -7.84 -0.39 5.62e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12928939 0.518 rs12445564 chr16:71943309 C/T cg03805757 chr16:71968109 PKD1L3 -0.95 -12.57 -0.56 4.62e-30 Post bronchodilator FEV1; LIHC cis rs11671005 0.693 rs11668821 chr19:58955813 G/A cg25952890 chr19:58913133 NA 0.71 7.75 0.39 1.09e-13 Mean platelet volume; LIHC cis rs11030122 0.673 rs66596383 chr11:3979745 C/T cg18678763 chr11:4115507 RRM1 -0.56 -8.31 -0.41 2.23e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs1577917 0.696 rs2842603 chr6:86336337 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.48 -9.28 -0.45 2.03e-18 Response to antipsychotic treatment; LIHC cis rs7534824 0.625 rs61780286 chr1:101359898 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.64 6.55 0.33 2.15e-10 Refractive astigmatism; LIHC cis rs490234 0.932 rs577026 chr9:128341023 C/T cg14078157 chr9:128172775 NA -0.35 -5.94 -0.31 6.83e-9 Mean arterial pressure; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg05025164 chr4:1340916 KIAA1530 0.78 11.96 0.54 8.59e-28 Longevity; LIHC cis rs903552 0.932 rs9806551 chr15:102008206 C/T cg19295451 chr15:102010161 PCSK6 -0.54 -7.65 -0.38 2.1e-13 Diabetic kidney disease; LIHC cis rs67981189 0.593 rs2097975 chr14:71480404 G/A cg15816911 chr14:71606274 NA 0.39 6.22 0.32 1.48e-9 Schizophrenia; LIHC cis rs9486715 1.000 rs9373985 chr6:97063522 C/G cg18709589 chr6:96969512 KIAA0776 -0.35 -6.11 -0.31 2.75e-9 Headache; LIHC cis rs1552244 0.572 rs57268864 chr3:10164233 C/A cg00149659 chr3:10157352 C3orf10 0.95 8.89 0.43 3.47e-17 Alzheimer's disease; LIHC cis rs7223966 1.000 rs2854219 chr17:61942682 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.85 0.35 3.44e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg02187348 chr16:89574699 SPG7 -0.59 -9.34 -0.45 1.29e-18 Multiple myeloma (IgH translocation); LIHC cis rs4665809 1.000 rs1550382 chr2:26266877 T/G cg04944784 chr2:26401820 FAM59B -0.71 -8.92 -0.43 2.85e-17 Gut microbiome composition (summer); LIHC cis rs12960505 0.506 rs9964174 chr18:51010181 A/C cg24270629 chr18:50823537 DCC -0.47 -6.44 -0.33 3.94e-10 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg07677032 chr17:61819896 STRADA 0.43 6.31 0.32 8.5e-10 Prudent dietary pattern; LIHC trans rs1814175 0.791 rs10839468 chr11:49986288 A/G cg15704280 chr7:45808275 SEPT13 -1.01 -23.93 -0.79 5e-75 Height; LIHC cis rs2153535 0.580 rs1115079 chr6:8449615 G/C cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC cis rs4853036 0.904 rs2278934 chr2:70121197 T/C cg02498382 chr2:70120550 SNRNP27 -0.43 -6.87 -0.35 3.02e-11 Colorectal or endometrial cancer; LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.99 -0.4 2.14e-14 Lymphocyte counts; LIHC trans rs7246657 0.943 rs1015849 chr19:37946180 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg11301795 chr4:187892539 NA 0.26 7.0 0.35 1.33e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2404602 0.692 rs4886503 chr15:77108874 C/T cg03037974 chr15:76606532 NA -0.75 -14.66 -0.62 4.18e-38 Blood metabolite levels; LIHC cis rs62402013 1 rs62402013 chr6:26915000 A/G cg12292205 chr6:26970375 C6orf41 0.45 7.68 0.38 1.66e-13 Schizophrenia; LIHC cis rs9534288 0.912 rs4942468 chr13:46618290 C/A cg15192986 chr13:46630673 CPB2 -0.57 -8.52 -0.42 5.29e-16 Blood protein levels; LIHC cis rs7937682 0.855 rs11213985 chr11:111581521 C/A cg09085632 chr11:111637200 PPP2R1B -1.08 -16.64 -0.67 5.81e-46 Primary sclerosing cholangitis; LIHC cis rs4721295 0.502 rs2058430 chr7:2206110 A/G cg02951883 chr7:2050386 MAD1L1 -0.59 -9.0 -0.44 1.64e-17 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg18357526 chr6:26021779 HIST1H4A 1.06 15.99 0.65 2.22e-43 Intelligence (multi-trait analysis); LIHC cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg16049864 chr8:95962084 TP53INP1 -0.66 -12.8 -0.57 6.34e-31 Type 2 diabetes; LIHC cis rs709400 0.628 rs11622320 chr14:103912194 A/T cg26031613 chr14:104095156 KLC1 0.77 9.97 0.47 9.88e-21 Body mass index; LIHC cis rs11577318 0.796 rs4625269 chr1:26626967 C/A cg00852783 chr1:26633632 UBXN11 0.42 6.8 0.35 4.66e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs10207060 0.500 rs7585903 chr2:240682481 A/C cg07506560 chr2:240697449 NA 0.41 6.15 0.32 2.2e-9 Obesity-related traits; LIHC cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.91 -10.39 -0.49 3.75e-22 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07721005 chr5:87564621 TMEM161B 0.45 6.55 0.33 2.07e-10 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16755220 chr16:12070685 RUNDC2A -0.42 -6.43 -0.33 4.36e-10 Pancreatic cancer; LIHC cis rs7769051 1.000 rs9493445 chr6:133125409 C/T cg07930552 chr6:133119739 C6orf192 0.65 6.45 0.33 3.78e-10 Type 2 diabetes nephropathy; LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg24503407 chr1:205819492 PM20D1 0.87 12.39 0.56 2.17e-29 Menarche (age at onset); LIHC cis rs769267 0.965 rs6511026 chr19:19391402 C/T cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg08219700 chr8:58056026 NA 0.52 6.39 0.33 5.41e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg11764359 chr7:65958608 NA 0.59 6.01 0.31 4.63e-9 Diabetic kidney disease; LIHC cis rs9733 0.818 rs4970924 chr1:150633079 A/G cg18016565 chr1:150552671 MCL1 -0.51 -10.49 -0.49 1.72e-22 Tonsillectomy; LIHC cis rs929354 0.685 rs1808217 chr7:157002741 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.87 0.3 1.02e-8 Body mass index; LIHC cis rs3096299 0.838 rs3102376 chr16:89402473 A/C cg06640241 chr16:89574553 SPG7 0.56 8.58 0.42 3.45e-16 Multiple myeloma (IgH translocation); LIHC cis rs61990749 0.597 rs176943 chr14:78175797 T/G cg23188588 chr14:78226832 SNW1;C14orf178 -0.61 -10.17 -0.48 2.11e-21 Fibroblast growth factor basic levels; LIHC cis rs7116495 1.000 rs7931941 chr11:71667604 C/T cg26138937 chr11:71823887 C11orf51 -0.67 -6.83 -0.35 3.92e-11 Severe influenza A (H1N1) infection; LIHC cis rs12477438 0.520 rs7604557 chr2:99747829 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC trans rs1005277 0.505 rs200936 chr10:38134935 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.86 0.35 3.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs2380220 0.574 rs7766765 chr6:95997362 G/A cg04719120 chr6:96025338 MANEA 0.47 5.72 0.3 2.37e-8 Behavioural disinhibition (generation interaction); LIHC cis rs6831256 1.000 rs10007119 chr4:3473066 A/G cg23495837 chr4:3480318 DOK7 -0.38 -6.81 -0.35 4.3e-11 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs4474465 0.688 rs7940720 chr11:78276674 C/T cg27205649 chr11:78285834 NARS2 0.48 7.36 0.37 1.42e-12 Alzheimer's disease (survival time); LIHC trans rs116095464 0.558 rs7725227 chr5:233517 G/A cg00938859 chr5:1591904 SDHAP3 0.58 7.08 0.36 8.15e-12 Breast cancer; LIHC cis rs7208859 0.673 rs9913782 chr17:29237384 A/G cg14067834 chr17:29058358 SUZ12P 0.69 6.65 0.34 1.16e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6942756 1.000 rs10954226 chr7:128953095 T/G cg02491457 chr7:128862824 NA -0.65 -9.49 -0.46 4.17e-19 White matter hyperintensity burden; LIHC cis rs7618501 1.000 rs1049256 chr3:49763338 T/C cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs7582180 0.663 rs6542930 chr2:100944383 T/A cg14675211 chr2:100938903 LONRF2 0.54 8.46 0.42 7.66e-16 Intelligence (multi-trait analysis); LIHC cis rs600806 0.850 rs12073497 chr1:109974450 A/C cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.85 -0.3 1.16e-8 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.681 rs2866362 chr11:49379316 A/G cg18944383 chr4:111397179 ENPEP 0.26 6.3 0.32 9.32e-10 Coronary artery disease; LIHC cis rs344364 0.511 rs1657132 chr16:1949924 C/T cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs477692 0.905 rs509041 chr10:131424948 A/G cg19680672 chr10:131412579 MGMT -0.42 -6.52 -0.33 2.46e-10 Response to temozolomide; LIHC cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg18357526 chr6:26021779 HIST1H4A 0.62 8.69 0.43 1.58e-16 Blood metabolite levels; LIHC cis rs28374715 0.681 rs28687846 chr15:41599902 C/T cg18705301 chr15:41695430 NDUFAF1 -1.17 -15.58 -0.64 9.57e-42 Ulcerative colitis; LIHC cis rs11645898 0.935 rs72787091 chr16:72190184 C/T cg14768367 chr16:72042858 DHODH -0.53 -5.78 -0.3 1.67e-8 Blood protein levels; LIHC cis rs11190604 1.000 rs2295770 chr10:102239829 G/A cg07080220 chr10:102295463 HIF1AN 0.5 7.09 0.36 7.71e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1144333 0.737 rs1144331 chr1:76272357 G/A cg10523679 chr1:76189770 ACADM -0.46 -6.75 -0.34 6.26e-11 Attention function in attention deficit hyperactive disorder; LIHC trans rs1814175 0.645 rs7952104 chr11:49964180 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs57221529 0.766 rs12521051 chr5:560440 A/G cg09021430 chr5:549028 NA 0.44 8.92 0.43 2.97e-17 Lung disease severity in cystic fibrosis; LIHC cis rs600806 0.778 rs10745357 chr1:110001876 G/C cg02415029 chr1:110025642 ATXN7L2 -0.53 -6.8 -0.35 4.54e-11 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.703 rs9911583 chr17:57210721 A/G cg12560992 chr17:57184187 TRIM37 -0.52 -7.3 -0.37 2.03e-12 Cognitive test performance; LIHC cis rs61990749 0.571 rs2364841 chr14:78284036 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.56 7.45 0.37 7.89e-13 Fibroblast growth factor basic levels; LIHC cis rs9733 0.596 rs2867301 chr1:150653795 C/T cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Tonsillectomy; LIHC cis rs12458462 0.892 rs58675823 chr18:77463672 G/A cg11879182 chr18:77439856 CTDP1 0.82 13.77 0.6 1.29e-34 Monocyte count; LIHC cis rs921968 0.565 rs4672897 chr2:219588134 A/G cg02985541 chr2:219472218 PLCD4 -0.38 -6.66 -0.34 1.07e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2749592 0.918 rs1208653 chr10:38253826 C/G cg25427524 chr10:38739819 LOC399744 0.58 10.26 0.49 1.05e-21 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7520050 0.966 rs785464 chr1:46523089 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.84 0.3 1.24e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7312933 0.618 rs6582390 chr12:42634586 C/T cg01256987 chr12:42539512 GXYLT1 -0.42 -6.97 -0.35 1.65e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs66569888 0.789 rs1317569 chr2:106735490 C/A cg16099169 chr2:106886729 NA -0.83 -8.85 -0.43 4.94e-17 Facial morphology (factor 23); LIHC cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg22105103 chr4:187893119 NA 0.34 8.48 0.42 7.07e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs748404 0.660 rs518288 chr15:43763999 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.88 0.39 4.43e-14 Lung cancer; LIHC trans rs11148252 0.740 rs9536046 chr13:52955899 T/G cg18335740 chr13:41363409 SLC25A15 0.35 6.06 0.31 3.57e-9 Lewy body disease; LIHC cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg07414643 chr4:187882934 NA 0.24 6.09 0.31 3.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.12 13.51 0.59 1.26e-33 Gut microbiome composition (summer); LIHC cis rs10870270 1.000 rs11146354 chr10:133774757 A/G cg26149184 chr10:133730230 NA 0.47 7.47 0.37 6.73e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs1005277 0.505 rs10827835 chr10:38150709 G/A cg17830980 chr10:43048298 ZNF37B 0.46 8.77 0.43 8.69e-17 Extrinsic epigenetic age acceleration; LIHC cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg25072359 chr17:41440525 NA 0.37 5.91 0.3 8.06e-9 Menopause (age at onset); LIHC cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg13395646 chr4:1353034 KIAA1530 -0.65 -9.37 -0.45 1.05e-18 Obesity-related traits; LIHC cis rs11724804 0.532 rs7657611 chr4:880558 G/C cg20916646 chr4:852691 GAK 0.59 7.77 0.39 9.29e-14 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs12893668 0.703 rs8017993 chr14:104047734 A/G cg19000871 chr14:103996768 TRMT61A -0.43 -7.21 -0.36 3.69e-12 Reticulocyte count; LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg20102877 chr2:27665638 KRTCAP3 -0.44 -5.98 -0.31 5.62e-9 Total body bone mineral density; LIHC cis rs1043515 0.935 rs2338115 chr17:36929578 C/T cg09592244 chr17:37024020 NA 0.37 6.01 0.31 4.88e-9 Height; LIHC cis rs2625529 0.761 rs8028532 chr15:72348054 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.92 -0.3 7.89e-9 Red blood cell count; LIHC cis rs1799949 0.683 rs55737636 chr17:41264739 C/T cg25072359 chr17:41440525 NA 0.38 5.98 0.31 5.68e-9 Menopause (age at onset); LIHC cis rs9910055 0.509 rs9916444 chr17:42313512 C/G cg13607699 chr17:42295918 UBTF 0.65 11.64 0.53 1.38e-26 Total body bone mineral density; LIHC cis rs9486715 1.000 rs9398148 chr6:97063555 A/G cg06623918 chr6:96969491 KIAA0776 -0.85 -14.12 -0.61 5.42e-36 Headache; LIHC cis rs7249142 0.562 rs10417796 chr19:19287072 A/G cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.36 -6.04 -0.31 4.11e-9 IgG glycosylation; LIHC cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.12 13.54 0.59 9.92e-34 Gut microbiome composition (summer); LIHC trans rs11148252 0.875 rs7987115 chr13:52962097 C/T cg18335740 chr13:41363409 SLC25A15 0.36 6.34 0.32 7.17e-10 Lewy body disease; LIHC cis rs10870270 0.917 rs9971362 chr10:133790150 T/C cg08754478 chr10:133766260 PPP2R2D -0.54 -7.88 -0.39 4.36e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg23172400 chr8:95962367 TP53INP1 -0.35 -8.02 -0.4 1.66e-14 Type 2 diabetes; LIHC cis rs10193935 0.901 rs10201586 chr2:42622594 C/G cg27598129 chr2:42591480 NA -0.72 -11.21 -0.52 4.6e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs4906332 1.000 rs8012127 chr14:103942762 G/A cg04998671 chr14:104000505 TRMT61A -0.46 -6.21 -0.32 1.53e-9 Coronary artery disease; LIHC cis rs6088590 0.965 rs6120727 chr20:33374102 T/C cg24642439 chr20:33292090 TP53INP2 0.78 10.6 0.5 6.72e-23 Coronary artery disease; LIHC cis rs1003719 0.680 rs2257091 chr21:38522618 G/T cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -11.12 -0.52 1.01e-24 Eye color traits; LIHC cis rs798554 0.757 rs1182172 chr7:2878103 G/A cg19346786 chr7:2764209 NA -0.44 -6.01 -0.31 4.64e-9 Height; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC cis rs7727544 0.684 rs274560 chr5:131719450 T/C cg24060327 chr5:131705240 SLC22A5 0.6 8.59 0.42 3.02e-16 Blood metabolite levels; LIHC cis rs9640161 0.742 rs11767726 chr7:150018096 A/C cg10018233 chr7:150070692 REPIN1 -0.53 -9.09 -0.44 8.02e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs9916302 0.904 rs12952384 chr17:37669536 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC cis rs11190604 1.000 rs2295780 chr10:102305965 A/G cg07080220 chr10:102295463 HIF1AN 0.52 7.14 0.36 5.67e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs4713118 0.512 rs2622319 chr6:28120401 G/C cg23485639 chr6:28045615 ZNF165 0.38 5.96 0.31 6.31e-9 Parkinson's disease; LIHC cis rs1003719 1.000 rs2154536 chr21:38492147 G/C cg10648535 chr21:38446584 PIGP;TTC3 0.75 11.45 0.53 6.52e-26 Eye color traits; LIHC cis rs910316 0.967 rs4903293 chr14:75656568 A/G cg08847533 chr14:75593920 NEK9 -0.84 -17.52 -0.69 1.73e-49 Height; LIHC cis rs992157 0.767 rs2014615 chr2:219171191 A/G cg00012203 chr2:219082015 ARPC2 0.81 13.14 0.58 3.19e-32 Colorectal cancer; LIHC cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg18225595 chr11:63971243 STIP1 -0.68 -8.45 -0.42 8.27e-16 Mean platelet volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02653728 chr5:132165751 NA 0.45 6.78 0.34 5.18e-11 Lung function (FEV1/FVC); LIHC cis rs3857067 0.806 rs12505596 chr4:95109600 A/G cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.11 -0.36 6.92e-12 QT interval; LIHC cis rs939574 0.512 rs10194278 chr2:220138408 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.61 7.42 0.37 9.22e-13 Platelet distribution width; LIHC cis rs986417 0.901 rs7157458 chr14:60999852 C/T cg27398547 chr14:60952738 C14orf39 0.83 9.59 0.46 1.95e-19 Gut microbiota (bacterial taxa); LIHC cis rs1559088 0.600 rs58173463 chr19:33596749 C/T cg17764715 chr19:33622953 WDR88 0.58 8.18 0.4 5.53e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9399135 0.967 rs4896121 chr6:135293645 T/C cg22676075 chr6:135203613 NA 0.39 6.36 0.33 6.53e-10 Red blood cell count; LIHC cis rs4665809 1.000 rs6720314 chr2:26334852 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.77 -9.58 -0.46 2.13e-19 Gut microbiome composition (summer); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06441968 chr1:40627537 RLF 0.43 6.43 0.33 4.39e-10 Lung function (FEV1/FVC); LIHC cis rs11190604 0.767 rs10883478 chr10:102162852 C/T cg07080220 chr10:102295463 HIF1AN 0.45 6.3 0.32 8.95e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs79149102 0.579 rs12591994 chr15:75320306 A/G cg09165964 chr15:75287851 SCAMP5 -0.62 -8.05 -0.4 1.36e-14 Lung cancer; LIHC cis rs6723226 0.806 rs2249109 chr2:32750879 G/A cg02381751 chr2:32503542 YIPF4 0.78 11.43 0.53 7.37e-26 Intelligence (multi-trait analysis); LIHC cis rs422249 0.512 rs174583 chr11:61609750 A/G cg07689907 chr11:61582574 FADS1 -0.37 -5.72 -0.3 2.3e-8 Trans fatty acid levels; LIHC cis rs7618501 1.000 rs11709680 chr3:49745188 C/T cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.34e-11 Intelligence (multi-trait analysis); LIHC cis rs7937890 0.874 rs6486191 chr11:14403739 G/A cg02886208 chr11:14281011 SPON1 -0.55 -8.12 -0.4 8.39e-15 Mitochondrial DNA levels; LIHC cis rs7258015 0.909 rs2304237 chr19:10446568 T/C cg13981319 chr19:10446556 ICAM3 0.47 7.14 0.36 5.66e-12 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs7616330 0.887 rs2100142 chr3:71112560 A/G cg01511742 chr3:71112437 FOXP1 -0.57 -7.85 -0.39 5.51e-14 QT interval; LIHC cis rs3736485 0.966 rs8042221 chr15:51774613 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.16 -0.32 2.08e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs769267 0.930 rs751856 chr19:19602945 A/G cg03709012 chr19:19516395 GATAD2A 1.0 18.21 0.7 2.91e-52 Tonsillectomy; LIHC cis rs9818758 0.607 rs34580506 chr3:49113713 C/A cg07636037 chr3:49044803 WDR6 -0.84 -8.52 -0.42 5.33e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs10751667 0.600 rs1128413 chr11:1010694 C/T cg10932868 chr11:921992 NA 0.32 6.05 0.31 3.87e-9 Alzheimer's disease (late onset); LIHC cis rs17401966 1.000 rs2275424 chr1:10356562 C/A cg19773385 chr1:10388646 KIF1B -0.48 -8.29 -0.41 2.64e-15 Hepatocellular carcinoma; LIHC cis rs7659604 0.502 rs13106764 chr4:122699630 C/G cg19671926 chr4:122722719 EXOSC9 0.54 8.51 0.42 5.73e-16 Type 2 diabetes; LIHC cis rs826838 0.874 rs10880943 chr12:38734317 C/T cg13010199 chr12:38710504 ALG10B 0.65 7.92 0.39 3.46e-14 Heart rate; LIHC cis rs11098499 0.754 rs17595608 chr4:120250506 C/T cg09307838 chr4:120376055 NA 0.71 11.14 0.52 8.4e-25 Corneal astigmatism; LIHC cis rs8044995 0.517 rs2863973 chr16:68409435 A/C cg09835421 chr16:68378352 PRMT7 -0.6 -7.01 -0.35 1.24e-11 Schizophrenia; LIHC trans rs208520 0.690 rs74707865 chr6:66717352 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.89 0.43 3.55e-17 Exhaled nitric oxide output; LIHC cis rs6547741 0.816 rs10201652 chr2:27874332 A/C cg27432699 chr2:27873401 GPN1 -0.85 -14.65 -0.62 4.54e-38 Oral cavity cancer; LIHC cis rs10256972 0.616 rs6957733 chr7:1106327 T/G cg16145915 chr7:1198662 ZFAND2A -0.26 -5.9 -0.3 8.73e-9 Longevity;Endometriosis; LIHC cis rs12497850 0.931 rs7626445 chr3:49114544 C/T cg06212747 chr3:49208901 KLHDC8B 0.57 7.45 0.37 7.81e-13 Parkinson's disease; LIHC trans rs1552244 0.572 rs68013239 chr3:10165711 G/T cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg03874509 chr1:107600012 PRMT6 0.73 11.65 0.53 1.26e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7843479 1.000 rs66824050 chr8:21815425 T/G cg17168535 chr8:21777572 XPO7 0.37 5.9 0.3 8.55e-9 Mean corpuscular volume; LIHC cis rs6582630 0.555 rs7956782 chr12:38603641 C/G cg26384229 chr12:38710491 ALG10B 0.87 10.03 0.48 6.16e-21 Drug-induced liver injury (flucloxacillin); LIHC cis rs9527 0.615 rs7073295 chr10:104672233 A/G cg15744005 chr10:104629667 AS3MT -0.29 -5.81 -0.3 1.41e-8 Arsenic metabolism; LIHC cis rs9457247 0.544 rs6920858 chr6:167464630 G/A cg23791538 chr6:167370224 RNASET2 -0.51 -7.81 -0.39 6.86e-14 Crohn's disease; LIHC trans rs916888 0.773 rs199445 chr17:44817408 C/T cg26692224 chr17:62915920 LRRC37A3 -0.71 -6.87 -0.35 2.97e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs7721647 0.853 rs6867266 chr5:90873294 T/C cg11567849 chr6:111751012 REV3L -0.49 -6.08 -0.31 3.14e-9 Breast cancer; LIHC cis rs734999 0.545 rs6684865 chr1:2546229 A/G cg18854424 chr1:2615690 NA -0.37 -8.42 -0.41 1.05e-15 Ulcerative colitis; LIHC cis rs751728 1.000 rs9394166 chr6:33751122 G/C cg25922239 chr6:33757077 LEMD2 0.45 7.54 0.38 4.19e-13 Crohn's disease; LIHC trans rs2727020 0.894 rs1880438 chr11:49370698 A/G cg15704280 chr7:45808275 SEPT13 -0.74 -11.25 -0.52 3.48e-25 Coronary artery disease; LIHC cis rs1552244 0.882 rs13084194 chr3:10031492 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.29 0.49 8.41e-22 Alzheimer's disease; LIHC cis rs7937682 0.961 rs11828343 chr11:111491322 A/G cg09085632 chr11:111637200 PPP2R1B 0.9 10.56 0.5 9.14e-23 Primary sclerosing cholangitis; LIHC cis rs644148 0.836 rs2686777 chr19:45000386 T/C cg15540054 chr19:45004280 ZNF180 -0.78 -11.67 -0.53 1.01e-26 Personality dimensions; LIHC cis rs7843479 0.898 rs4311656 chr8:21802276 T/G cg17168535 chr8:21777572 XPO7 0.38 6.04 0.31 4.05e-9 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg12463550 chr7:65579703 CRCP 0.69 7.27 0.37 2.42e-12 Diabetic kidney disease; LIHC cis rs9309473 0.607 rs11686504 chr2:73579812 T/C cg20560298 chr2:73613845 ALMS1 -0.44 -7.01 -0.35 1.31e-11 Metabolite levels; LIHC cis rs2439831 1.000 rs2439841 chr15:43734749 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.61 8.7 0.43 1.4e-16 Lung cancer in ever smokers; LIHC cis rs7726839 0.578 rs10080150 chr5:593160 C/T cg16447950 chr5:562315 NA 0.38 6.97 0.35 1.61e-11 Obesity-related traits; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg08837587 chr8:30601672 UBXN8 -0.66 -6.92 -0.35 2.24e-11 Obesity-related traits; LIHC cis rs34245846 0.704 rs11264280 chr1:154862952 C/T cg03351412 chr1:154909251 PMVK -0.59 -7.23 -0.36 3.22e-12 Atrial fibrillation; LIHC cis rs10751667 0.666 rs7124480 chr11:971601 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.7 -0.62 3.07e-38 Alzheimer's disease (late onset); LIHC cis rs992157 1.000 rs992157 chr2:219154781 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.8 -12.89 -0.57 2.97e-31 Colorectal cancer; LIHC cis rs1023500 0.505 rs134901 chr22:42683520 C/T cg15557168 chr22:42548783 NA -0.36 -6.09 -0.31 2.97e-9 Schizophrenia; LIHC cis rs35883536 1.000 rs12410168 chr1:101115321 G/A cg14515779 chr1:101123966 NA -0.67 -13.36 -0.59 4.66e-33 Monocyte count; LIHC cis rs12594515 1.000 rs12592190 chr15:45994028 G/A cg19682013 chr15:45996608 NA 0.39 6.67 0.34 1.01e-10 Waist circumference;Weight; LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg17178900 chr1:205818956 PM20D1 0.74 10.89 0.51 6.79e-24 Menarche (age at onset); LIHC cis rs8060686 0.545 rs8056649 chr16:68260083 A/G cg05110241 chr16:68378359 PRMT7 0.53 6.29 0.32 9.74e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs6598955 0.724 rs12757113 chr1:26597144 C/T cg04990556 chr1:26633338 UBXN11 -0.65 -10.48 -0.49 1.84e-22 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24419099 chr11:47270565 NR1H3;ACP2 0.49 6.89 0.35 2.77e-11 Pancreatic cancer; LIHC cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg13607699 chr17:42295918 UBTF 0.44 7.05 0.36 9.71e-12 Total body bone mineral density; LIHC cis rs6429082 0.509 rs2789362 chr1:235521235 A/G cg26050004 chr1:235667680 B3GALNT2 0.42 6.33 0.32 7.79e-10 Adiposity; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19482537 chr5:156692823 CYFIP2 0.46 7.23 0.36 3.18e-12 Calcium levels; LIHC cis rs7572733 0.534 rs700662 chr2:198668751 T/C cg03934865 chr2:198174659 NA 0.46 6.61 0.34 1.47e-10 Dermatomyositis; LIHC cis rs743757 0.816 rs6792502 chr3:50531201 C/A cg12708802 chr3:50388878 TUSC4;CYB561D2 0.42 6.21 0.32 1.52e-9 Diastolic blood pressure; LIHC cis rs644148 0.785 rs118112019 chr19:44965091 T/G cg15540054 chr19:45004280 ZNF180 0.78 10.73 0.5 2.44e-23 Personality dimensions; LIHC cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs9503598 0.502 rs6938209 chr6:3430487 G/A cg00476032 chr6:3446245 SLC22A23 -0.32 -5.86 -0.3 1.08e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs1055129 0.537 rs1135640 chr17:73949540 C/G cg14829360 chr17:73884958 NA 0.37 6.21 0.32 1.52e-9 White matter hyperintensity burden; LIHC cis rs34779708 0.931 rs4934524 chr10:35270921 G/C cg03585969 chr10:35415529 CREM 0.86 13.01 0.58 9.87e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs796364 0.625 rs4673837 chr2:201131159 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.55 6.54 0.33 2.19e-10 Schizophrenia; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg20349687 chr2:88927127 EIF2AK3 -0.43 -6.54 -0.33 2.22e-10 Body mass index; LIHC trans rs7677751 0.806 rs7679903 chr4:55097373 T/C cg17183009 chr3:120277827 NA 0.52 6.09 0.31 3.02e-9 Corneal astigmatism; LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC trans rs10512049 0.655 rs11521830 chr9:78290840 A/C cg02083989 chr12:65153459 GNS 0.86 6.77 0.34 5.63e-11 Total ventricular volume (Alzheimer's disease interaction); LIHC cis rs4638749 0.677 rs10190865 chr2:108843624 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs10489202 0.657 rs201541 chr1:167992344 T/A cg24449463 chr1:168025552 DCAF6 -0.63 -9.51 -0.46 3.57e-19 Schizophrenia; LIHC cis rs9916302 0.851 rs612209 chr17:37442713 G/C cg00129232 chr17:37814104 STARD3 0.39 6.23 0.32 1.34e-9 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs1550582 1.000 rs1550582 chr8:135542084 A/G cg17885191 chr8:135476712 NA -0.34 -5.77 -0.3 1.82e-8 Educational attainment; LIHC cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg21782813 chr7:2030301 MAD1L1 0.41 6.85 0.35 3.42e-11 Bipolar disorder and schizophrenia; LIHC cis rs644799 0.710 rs56384142 chr11:95502075 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.25 0.58 1.22e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg13409248 chr3:40428643 ENTPD3 0.5 8.35 0.41 1.74e-15 Renal cell carcinoma; LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.7 10.01 0.48 7.71e-21 Lymphocyte counts; LIHC trans rs2243480 1.000 rs2420171 chr7:65637760 T/C cg10756647 chr7:56101905 PSPH -1.08 -13.29 -0.58 8.75e-33 Diabetic kidney disease; LIHC cis rs9916302 0.904 rs2061342 chr17:37405657 T/G cg03013999 chr17:37608204 MED1 0.34 5.75 0.3 2.03e-8 Glomerular filtration rate (creatinine); LIHC cis rs7707921 0.881 rs4391141 chr5:81263522 T/A cg15871215 chr5:81402204 ATG10 -0.61 -5.82 -0.3 1.35e-8 Breast cancer; LIHC cis rs12744310 0.887 rs12047161 chr1:41807528 G/T cg03387723 chr1:41708464 SCMH1 -0.32 -5.9 -0.3 8.91e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs769267 0.965 rs2074296 chr19:19373689 A/G cg03709012 chr19:19516395 GATAD2A 0.92 14.84 0.63 8.3e-39 Tonsillectomy; LIHC cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.95e-9 Menopause (age at onset); LIHC cis rs10791097 0.694 rs4937583 chr11:130741606 A/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs589448 0.872 rs315111 chr12:69784695 G/A cg22834771 chr12:69754056 YEATS4 -0.55 -10.07 -0.48 4.59e-21 Cerebrospinal fluid biomarker levels; LIHC cis rs10504229 0.953 rs6985942 chr8:58173412 T/C cg02290350 chr8:58132656 NA 0.41 8.7 0.43 1.43e-16 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6921964 chr6:8446395 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.66 0.53 1.09e-26 Motion sickness; LIHC cis rs11718455 0.960 rs11921995 chr3:44017301 C/A cg08738300 chr3:44038990 NA 0.52 8.94 0.44 2.54e-17 Coronary artery disease; LIHC cis rs7772486 0.597 rs2246132 chr6:146182515 C/G cg13319975 chr6:146136371 FBXO30 -0.55 -8.88 -0.43 3.9e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.754 rs4896839 chr6:146019689 T/G cg05347473 chr6:146136440 FBXO30 -0.37 -5.91 -0.3 8.48e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12479064 0.505 rs62153764 chr2:99818612 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -9.42 -0.45 6.71e-19 Chronic sinus infection; LIHC cis rs4906332 0.966 rs59858038 chr14:103867102 C/T cg19000871 chr14:103996768 TRMT61A -0.45 -7.56 -0.38 3.63e-13 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10345131 chr15:91475918 UNC45A;HDDC3 0.45 6.51 0.33 2.63e-10 Lung function (FEV1/FVC); LIHC trans rs62103177 0.759 rs7227794 chr18:77610925 C/T cg05926928 chr17:57297772 GDPD1 1.25 13.58 0.59 6.5e-34 Opioid sensitivity; LIHC cis rs9783347 0.857 rs2124374 chr11:18313911 A/C cg15585147 chr11:18324498 HPS5 0.45 6.88 0.35 2.92e-11 Pancreatic cancer; LIHC cis rs9560113 0.550 rs1163633 chr13:112231561 G/T cg10483660 chr13:112241077 NA -0.24 -6.29 -0.32 9.54e-10 Menarche (age at onset); LIHC cis rs904251 0.523 rs1776455 chr6:37482923 A/T cg25019722 chr6:37503610 NA -0.31 -5.74 -0.3 2.09e-8 Cognitive performance; LIHC cis rs2479724 0.875 rs2253961 chr6:41827011 A/G cg17623882 chr6:41773611 USP49 -0.55 -8.81 -0.43 6.4e-17 Menarche (age at onset); LIHC cis rs13086611 1 rs13086611 chr3:49385417 A/T cg03060546 chr3:49711283 APEH -0.48 -6.56 -0.33 2.03e-10 Educational attainment; LIHC cis rs4819052 0.851 rs8130285 chr21:46671701 G/C cg22633049 chr21:46681294 NA -0.37 -6.46 -0.33 3.6e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9733 0.526 rs11204696 chr1:150658721 T/C cg18016565 chr1:150552671 MCL1 0.59 11.57 0.53 2.44e-26 Tonsillectomy; LIHC cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg07424592 chr7:64974309 NA 0.83 9.54 0.46 2.85e-19 Diabetic kidney disease; LIHC cis rs2370759 1.000 rs75984055 chr10:32591276 T/C cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs2777491 0.915 rs28578057 chr15:41621921 G/A cg18705301 chr15:41695430 NDUFAF1 -0.55 -8.15 -0.4 7.18e-15 Ulcerative colitis; LIHC cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.36 0.45 1.11e-18 Bipolar disorder; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg01339444 chr6:118972232 C6orf204 0.59 5.82 0.3 1.32e-8 Diastolic blood pressure; LIHC cis rs600626 0.529 rs2008476 chr11:75470813 C/T cg24262691 chr11:75473276 NA 0.43 6.37 0.33 6e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs7617773 0.780 rs36121690 chr3:48345511 C/T cg11946769 chr3:48343235 NME6 0.91 11.37 0.52 1.23e-25 Coronary artery disease; LIHC cis rs72781680 0.752 rs72796116 chr2:23913769 C/T cg08917208 chr2:24149416 ATAD2B 0.96 8.01 0.4 1.84e-14 Lymphocyte counts; LIHC cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg03264133 chr6:25882463 NA -0.69 -8.98 -0.44 1.8e-17 Intelligence (multi-trait analysis); LIHC cis rs986417 1.000 rs11845369 chr14:60944959 A/G cg27398547 chr14:60952738 C14orf39 0.8 9.07 0.44 9.75e-18 Gut microbiota (bacterial taxa); LIHC cis rs1348850 0.914 rs11893448 chr2:178280013 T/C cg27490568 chr2:178487706 NA 0.36 5.72 0.3 2.31e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs79149102 0.579 rs6495146 chr15:75367630 A/T cg09165964 chr15:75287851 SCAMP5 -0.54 -7.16 -0.36 5.06e-12 Lung cancer; LIHC cis rs7100689 0.646 rs4468295 chr10:82119276 C/G cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10791097 0.667 rs12363163 chr11:130744509 A/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg10896456 chr17:42255109 ASB16;C17orf65 -0.52 -9.41 -0.45 7.66e-19 Total body bone mineral density; LIHC cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg27170947 chr2:26402098 FAM59B 0.66 8.34 0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs12586317 0.547 rs116499019 chr14:35441931 T/C cg16230307 chr14:35515116 FAM177A1 0.77 12.8 0.57 6.22e-31 Psoriasis; LIHC trans rs783540 0.592 rs2567632 chr15:83284804 A/G cg18393722 chr15:85113863 UBE2QP1 -0.43 -6.68 -0.34 9.55e-11 Schizophrenia; LIHC cis rs2404602 0.735 rs2436994 chr15:76801063 G/C cg03037974 chr15:76606532 NA -0.59 -10.19 -0.48 1.76e-21 Blood metabolite levels; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.6 0.38 2.91e-13 Prudent dietary pattern; LIHC trans rs1814175 0.727 rs2140597 chr11:49873946 G/A cg03929089 chr4:120376271 NA -0.89 -18.62 -0.71 6.08e-54 Height; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs1580019 0.587 rs10951338 chr7:32560089 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.2 0.32 1.66e-9 Cognitive ability; LIHC cis rs6973256 0.637 rs12539993 chr7:133418799 C/T cg03336402 chr7:133662267 EXOC4 -0.38 -5.89 -0.3 9.13e-9 Intelligence (multi-trait analysis); LIHC cis rs17125944 0.505 rs3783447 chr14:53191647 G/A cg13660082 chr14:53194042 PSMC6 -0.45 -7.77 -0.39 9.3e-14 Alzheimer's disease (late onset); LIHC cis rs9549328 0.718 rs7139939 chr13:113634409 G/A cg18289306 chr13:113640169 MCF2L 0.41 6.58 0.34 1.75e-10 Systolic blood pressure; LIHC cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg22800045 chr5:56110881 MAP3K1 -0.68 -8.77 -0.43 8.46e-17 Initial pursuit acceleration; LIHC cis rs4919694 0.901 rs74376228 chr10:104677662 G/C cg04362960 chr10:104952993 NT5C2 1.09 7.82 0.39 6.53e-14 Arsenic metabolism; LIHC cis rs60871478 0.945 rs62432254 chr7:804175 C/T cg27478167 chr7:817139 HEATR2 -0.41 -5.83 -0.3 1.32e-8 Cerebrospinal P-tau181p levels; LIHC cis rs8180040 0.705 rs73069104 chr3:47280733 T/C cg16586182 chr3:47516702 SCAP 0.5 8.72 0.43 1.21e-16 Colorectal cancer; LIHC cis rs79057730 0.599 rs9458 chr7:825494 A/G cg06242242 chr7:766104 PRKAR1B;HEATR2 -0.77 -8.68 -0.43 1.59e-16 Initial pursuit acceleration; LIHC cis rs6502050 0.799 rs34448080 chr17:80121275 A/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg08392591 chr16:89556376 ANKRD11 0.55 8.55 0.42 4.02e-16 Multiple myeloma (IgH translocation); LIHC cis rs986417 0.901 rs12886086 chr14:61042091 A/G cg27398547 chr14:60952738 C14orf39 0.73 7.88 0.39 4.46e-14 Gut microbiota (bacterial taxa); LIHC cis rs2354432 0.607 rs3766524 chr1:146729093 A/G cg25205988 chr1:146714368 CHD1L -0.91 -10.92 -0.51 5.23e-24 Mitochondrial DNA levels; LIHC cis rs155076 0.938 rs536209 chr13:21847714 C/T cg11317459 chr13:21872234 NA -1.17 -13.04 -0.58 8.22e-32 White matter hyperintensity burden; LIHC cis rs9517313 0.615 rs4772079 chr13:99090837 C/G cg07423050 chr13:99094983 FARP1 -0.6 -11.57 -0.53 2.35e-26 Neuroticism; LIHC cis rs15676 0.783 rs7860949 chr9:131586883 C/T cg00228799 chr9:131580591 ENDOG -0.48 -6.93 -0.35 2.16e-11 Blood metabolite levels; LIHC cis rs55665837 0.540 rs12290926 chr11:14695046 A/G cg00085434 chr11:14927489 NA 0.41 5.86 0.3 1.07e-8 Vitamin D levels; LIHC cis rs7131987 0.650 rs16934135 chr12:29483963 T/G cg14222432 chr12:29376421 FAR2 0.36 6.96 0.35 1.72e-11 QT interval; LIHC trans rs4566357 0.615 rs3769642 chr2:227917323 T/C cg16088116 chr21:44841560 SIK1 -0.42 -6.52 -0.33 2.59e-10 Coronary artery disease; LIHC cis rs8180040 0.652 rs13077398 chr3:47011120 G/C cg16586182 chr3:47516702 SCAP -0.47 -8.5 -0.42 6.1e-16 Colorectal cancer; LIHC cis rs2404602 0.692 rs12913810 chr15:77166675 T/C cg03037974 chr15:76606532 NA 0.74 14.54 0.62 1.27e-37 Blood metabolite levels; LIHC cis rs244293 1.000 rs2628313 chr17:53235352 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.08 -0.36 8.38e-12 Menarche (age at onset); LIHC cis rs11122272 0.735 rs2572249 chr1:231514829 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.78e-23 Hemoglobin concentration; LIHC cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg18252515 chr7:66147081 NA -1.26 -16.63 -0.67 6.04e-46 Diabetic kidney disease; LIHC cis rs1670533 0.872 rs11727135 chr4:1051803 G/C cg27284194 chr4:1044797 NA 0.6 8.96 0.44 2.09e-17 Recombination rate (females); LIHC trans rs2288327 0.643 rs1559908 chr2:179336347 C/T cg14011486 chr1:26737247 LIN28 -0.62 -8.89 -0.43 3.45e-17 Atrial fibrillation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25733613 chr11:111637437 PPP2R1B 0.44 6.16 0.32 2.07e-9 Lung function (FEV1/FVC); LIHC cis rs12188164 0.561 rs2251843 chr5:457955 C/T cg07599136 chr5:415885 AHRR -0.39 -6.77 -0.34 5.55e-11 Cystic fibrosis severity; LIHC cis rs910316 0.967 rs175502 chr14:75533679 A/G cg08847533 chr14:75593920 NEK9 -0.89 -19.7 -0.73 2.86e-58 Height; LIHC trans rs208520 0.690 rs207108 chr6:66794096 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs8180040 0.715 rs6772670 chr3:47191349 G/A cg02527881 chr3:46936655 PTH1R -0.32 -6.33 -0.32 7.83e-10 Colorectal cancer; LIHC cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs4908768 0.906 rs12405049 chr1:8626117 C/T cg20416874 chr1:8611966 RERE 0.57 8.72 0.43 1.22e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7927592 0.913 rs11228268 chr11:68287447 A/T cg20283391 chr11:68216788 NA -0.52 -7.75 -0.39 1.05e-13 Total body bone mineral density; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06090383 chr4:174292579 SAP30 -0.5 -6.33 -0.32 7.71e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg15691649 chr6:25882328 NA 0.45 5.77 0.3 1.78e-8 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.591 rs162390 chr21:44936826 C/T cg04455712 chr21:45112962 RRP1B 0.43 7.08 0.36 8.36e-12 Mean corpuscular volume; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs4713118 0.516 rs6931858 chr6:28078411 A/T cg16479474 chr6:28041457 NA 0.4 5.76 0.3 1.86e-8 Parkinson's disease; LIHC cis rs8067354 0.645 rs2665400 chr17:57880201 G/A cg13753209 chr17:57696993 CLTC 0.73 11.56 0.53 2.62e-26 Hemoglobin concentration; LIHC cis rs796364 0.806 rs34510964 chr2:201010676 C/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.54 -6.24 -0.32 1.28e-9 Schizophrenia; LIHC cis rs11122272 0.668 rs2472261 chr1:231505701 G/A cg06096015 chr1:231504339 EGLN1 0.48 8.78 0.43 7.71e-17 Hemoglobin concentration; LIHC cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg12292205 chr6:26970375 C6orf41 -0.41 -7.06 -0.36 9.22e-12 Schizophrenia; LIHC cis rs6942756 0.747 rs691124 chr7:129098439 A/G cg02491457 chr7:128862824 NA -0.57 -8.93 -0.43 2.59e-17 White matter hyperintensity burden; LIHC cis rs11122272 0.701 rs2491402 chr1:231494338 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.68e-19 Hemoglobin concentration; LIHC cis rs8062405 0.755 rs4787457 chr16:28555400 A/G cg00204512 chr16:28754710 NA 0.41 7.16 0.36 4.9e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12887734 0.546 rs4900597 chr14:104266664 A/G cg08213375 chr14:104286397 PPP1R13B -0.53 -9.43 -0.45 6.37e-19 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg14160804 chr18:12703040 PSMG2;CEP76 -0.49 -6.09 -0.31 3.11e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs3617 0.539 rs9825369 chr3:52953311 T/C cg18404041 chr3:52824283 ITIH1 0.39 5.81 0.3 1.43e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs2637266 0.686 rs1660915 chr10:78525318 T/A cg18941641 chr10:78392320 NA 0.28 6.05 0.31 3.77e-9 Pulmonary function; LIHC trans rs911555 0.723 rs12436956 chr14:103852607 G/T cg17675199 chr6:35436792 RPL10A -0.41 -8.56 -0.42 3.98e-16 Intelligence (multi-trait analysis); LIHC cis rs477895 0.838 rs12794145 chr11:64006484 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 9.41 0.45 7.45e-19 Mean platelet volume; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17935035 chr15:40763388 CHST14 -0.48 -6.21 -0.32 1.51e-9 Systolic blood pressure; LIHC cis rs8017423 0.967 rs11627528 chr14:90719697 C/A cg04374321 chr14:90722782 PSMC1 -0.75 -14.39 -0.61 4.74e-37 Mortality in heart failure; LIHC cis rs61990749 0.597 rs28534379 chr14:78172140 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.36 -0.49 4.8e-22 Fibroblast growth factor basic levels; LIHC cis rs4746818 1.000 rs4746817 chr10:70882515 T/C cg11621586 chr10:70884670 VPS26A 0.8 11.47 0.53 5.69e-26 Left atrial antero-posterior diameter; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11599998 chr3:160283537 KPNA4 -0.46 -6.42 -0.33 4.47e-10 Bilirubin levels; LIHC trans rs6912958 0.712 rs4706294 chr6:88317675 G/C cg23605328 chr1:201951606 RNPEP 0.39 6.1 0.31 2.92e-9 Monocyte percentage of white cells; LIHC cis rs10847980 0.590 rs1979236 chr12:123325993 G/A cg07706471 chr12:123319906 HIP1R 0.72 8.13 0.4 7.75e-15 Adiponectin levels; LIHC cis rs172166 0.694 rs536704 chr6:28092603 T/G cg16479474 chr6:28041457 NA 0.38 6.34 0.32 7.08e-10 Cardiac Troponin-T levels; LIHC cis rs937213 0.573 rs12592831 chr15:40302441 G/A cg16127683 chr15:40268777 EIF2AK4 -0.36 -5.89 -0.3 9.23e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs12701220 0.948 rs10275712 chr7:1082918 G/A cg00990874 chr7:1149470 C7orf50 -0.65 -8.93 -0.44 2.59e-17 Bronchopulmonary dysplasia; LIHC cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg05665937 chr4:1216051 CTBP1 0.45 6.05 0.31 3.86e-9 Obesity-related traits; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC trans rs11039798 0.588 rs59777067 chr11:49015350 C/T cg15704280 chr7:45808275 SEPT13 0.6 6.76 0.34 5.96e-11 Axial length; LIHC cis rs2976388 0.556 rs4736321 chr8:143822194 C/T cg24634471 chr8:143751801 JRK -0.43 -5.92 -0.3 7.86e-9 Urinary tract infection frequency; LIHC cis rs7572733 0.515 rs11887138 chr2:198805838 T/A cg03934865 chr2:198174659 NA 0.46 6.79 0.34 5.08e-11 Dermatomyositis; LIHC cis rs12130219 0.500 rs4845743 chr1:152184149 A/G cg25272121 chr1:152190972 HRNR -0.25 -5.74 -0.3 2.12e-8 Inflammatory skin disease; LIHC cis rs208520 0.690 rs10455595 chr6:66738034 T/C cg07460842 chr6:66804631 NA 0.78 9.07 0.44 9.76e-18 Exhaled nitric oxide output; LIHC cis rs7582720 1.000 rs72934765 chr2:203758551 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.31 0.32 8.68e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs769267 0.930 rs892022 chr19:19613381 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.94 0.39 3.03e-14 Tonsillectomy; LIHC cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg08392591 chr16:89556376 ANKRD11 0.58 9.33 0.45 1.33e-18 Multiple myeloma (IgH translocation); LIHC cis rs6558530 0.692 rs6558525 chr8:1702523 A/G cg24391279 chr8:1708526 NA -0.35 -5.85 -0.3 1.14e-8 Systolic blood pressure; LIHC cis rs4319547 0.695 rs6488958 chr12:122880704 A/G cg05707623 chr12:122985044 ZCCHC8 -0.53 -6.95 -0.35 1.88e-11 Body mass index; LIHC cis rs2730245 1.000 rs2730245 chr7:158724789 G/C cg24397884 chr7:158709396 WDR60 -0.43 -6.55 -0.33 2.15e-10 Height; LIHC trans rs208520 0.526 rs6455072 chr6:66797215 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.03 -20.09 -0.74 7.73e-60 Exhaled nitric oxide output; LIHC cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg13944838 chr5:179740914 GFPT2 0.51 7.21 0.36 3.71e-12 Height; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.33 0.41 1.94e-15 Height; LIHC cis rs16854884 0.586 rs11914731 chr3:143725594 A/G cg06585982 chr3:143692056 C3orf58 0.57 7.35 0.37 1.43e-12 Economic and political preferences (feminism/equality); LIHC cis rs34172651 0.917 rs200536 chr16:24749203 G/A cg04756594 chr16:24857601 SLC5A11 -0.46 -7.26 -0.37 2.64e-12 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.765 rs1794141 chr11:49914135 G/C cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs919433 0.680 rs788022 chr2:198280586 T/C cg10820045 chr2:198174542 NA 0.55 8.95 0.44 2.22e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3806843 0.801 rs801171 chr5:140115303 G/A cg19875535 chr5:140030758 IK -0.39 -6.3 -0.32 8.97e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -6.09 -0.31 2.99e-9 Bipolar disorder and schizophrenia; LIHC trans rs62103177 0.810 rs62103194 chr18:77629482 G/A cg05926928 chr17:57297772 GDPD1 1.1 11.26 0.52 3.23e-25 Opioid sensitivity; LIHC cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg12463550 chr7:65579703 CRCP 0.68 7.14 0.36 5.69e-12 Diabetic kidney disease; LIHC cis rs924607 1.000 rs4045344 chr5:595870 G/T cg04221910 chr5:616842 CEP72 -0.42 -7.34 -0.37 1.53e-12 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg00149659 chr3:10157352 C3orf10 0.73 7.48 0.38 6.15e-13 Alzheimer's disease; LIHC cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg24209194 chr3:40518798 ZNF619 0.52 7.7 0.38 1.45e-13 Renal cell carcinoma; LIHC cis rs8027181 0.839 rs2277598 chr15:73027478 T/C cg25632853 chr15:73088954 NA 0.36 5.94 0.31 6.95e-9 Triglyceride levels; LIHC cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.46 -6.38 -0.33 5.86e-10 Bipolar disorder; LIHC cis rs11971779 0.616 rs2883772 chr7:139072756 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs4586057 0.514 rs12246757 chr10:92634383 A/G cg14313238 chr10:92632228 RPP30 0.37 6.08 0.31 3.22e-9 Economic and political preferences (time); LIHC cis rs7208859 0.623 rs216423 chr17:28942109 G/C cg13385521 chr17:29058706 SUZ12P 0.58 5.87 0.3 1.01e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs986417 1.000 rs6573320 chr14:61092022 A/G cg27398547 chr14:60952738 C14orf39 0.58 5.99 0.31 5.29e-9 Gut microbiota (bacterial taxa); LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg11062466 chr8:58055876 NA 0.49 7.14 0.36 5.5e-12 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg20295408 chr7:1910781 MAD1L1 -0.41 -5.96 -0.31 6.22e-9 Bipolar disorder and schizophrenia; LIHC cis rs1707322 1.000 rs4660318 chr1:46334876 A/G cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2224391 1.000 rs9504370 chr6:5261601 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.42 -6.28 -0.32 1.02e-9 Height; LIHC cis rs7572733 0.534 rs11890137 chr2:198816662 G/A cg03934865 chr2:198174659 NA 0.48 6.9 0.35 2.57e-11 Dermatomyositis; LIHC cis rs903552 1.000 rs8043379 chr15:102005837 A/G cg06707286 chr15:102010195 PCSK6 -0.44 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC cis rs763121 0.853 rs5757204 chr22:39046700 A/C cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC trans rs2727020 0.702 rs609054 chr11:49219725 C/G cg03929089 chr4:120376271 NA 0.79 13.92 0.6 3.27e-35 Coronary artery disease; LIHC cis rs9303401 0.659 rs17822807 chr17:56687190 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.97 12.98 0.57 1.38e-31 Cognitive test performance; LIHC cis rs875971 0.825 rs6951503 chr7:65718936 T/G cg18876405 chr7:65276391 NA -0.34 -6.21 -0.32 1.57e-9 Aortic root size; LIHC trans rs7613875 0.620 rs7634441 chr3:50071677 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.42 -6.48 -0.33 3.26e-10 Body mass index; LIHC cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 11.6 0.53 1.85e-26 Alzheimer's disease; LIHC trans rs10242455 0.557 rs2404487 chr7:99038057 G/A cg09045935 chr12:6379348 NA 0.83 6.85 0.35 3.36e-11 Blood metabolite levels; LIHC cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.68 0.34 9.43e-11 Bipolar disorder; LIHC cis rs34779708 0.931 rs67261877 chr10:35386340 T/A cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs1005277 0.579 rs2103938 chr10:38493998 T/G cg23533926 chr12:111358616 MYL2 -0.35 -6.78 -0.34 5.43e-11 Extrinsic epigenetic age acceleration; LIHC cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg09323728 chr8:95962352 TP53INP1 -0.28 -6.06 -0.31 3.54e-9 Type 2 diabetes; LIHC cis rs8017423 1.000 rs4904644 chr14:90665689 A/G cg04374321 chr14:90722782 PSMC1 -0.75 -14.2 -0.61 2.6e-36 Mortality in heart failure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20264566 chr11:10316295 SBF2 0.46 6.31 0.32 8.71e-10 Lung function (FEV1/FVC); LIHC cis rs875971 0.520 rs2420597 chr7:65915986 A/G cg18252515 chr7:66147081 NA -0.41 -5.8 -0.3 1.47e-8 Aortic root size; LIHC cis rs62380364 0.602 rs610217 chr5:88065263 G/A cg22951263 chr5:87985283 NA -0.41 -7.18 -0.36 4.42e-12 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg11060661 chr22:24314208 DDT;DDTL 0.6 10.45 0.49 2.26e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4474465 1.000 rs7950813 chr11:78215082 A/T cg02023728 chr11:77925099 USP35 -0.33 -5.9 -0.3 8.97e-9 Alzheimer's disease (survival time); LIHC cis rs12477438 0.765 rs1054042 chr2:99614396 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.58 -0.38 3.34e-13 Chronic sinus infection; LIHC cis rs1003719 0.762 rs6517402 chr21:38447423 A/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs2635047 0.875 rs2251948 chr18:44681356 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.45 6.03 0.31 4.21e-9 Educational attainment; LIHC cis rs1113500 0.814 rs1592282 chr1:108601365 T/C cg06207961 chr1:108661230 NA 0.31 5.71 0.3 2.44e-8 Growth-regulated protein alpha levels; LIHC cis rs6782228 0.606 rs2811500 chr3:128366256 C/T cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs6867032 1.000 rs6867032 chr5:2015103 G/T cg26168224 chr5:2018326 NA -0.33 -8.47 -0.42 7.27e-16 Gut microbiome composition (winter); LIHC cis rs7520050 0.581 rs3855959 chr1:46633874 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.48 7.41 0.37 1.03e-12 Red blood cell count;Reticulocyte count; LIHC cis rs2073300 1.000 rs6106656 chr20:23444301 A/G cg16736954 chr20:23401023 NAPB 0.52 5.84 0.3 1.19e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1005277 0.565 rs2474565 chr10:38380828 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.96 -0.31 6.15e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7208859 0.623 rs56378576 chr17:29010120 C/T cg14067834 chr17:29058358 SUZ12P 0.62 6.08 0.31 3.18e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4555082 1.000 rs7146643 chr14:105757392 A/G cg06808227 chr14:105710500 BRF1 -0.57 -7.91 -0.39 3.65e-14 Mean platelet volume;Platelet distribution width; LIHC cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg06481639 chr22:41940642 POLR3H -0.66 -6.3 -0.32 9.4e-10 Vitiligo; LIHC cis rs600806 0.854 rs367586 chr1:109850122 C/A cg16275483 chr1:110013120 SYPL2 -0.51 -6.22 -0.32 1.47e-9 Intelligence (multi-trait analysis); LIHC cis rs910316 0.726 rs61979167 chr14:75663610 C/T cg08847533 chr14:75593920 NEK9 -0.82 -16.05 -0.66 1.27e-43 Height; LIHC cis rs8141529 0.732 rs6005881 chr22:29183133 A/G cg15103426 chr22:29168792 CCDC117 0.67 11.52 0.53 3.57e-26 Lymphocyte counts; LIHC cis rs7208859 0.623 rs216445 chr17:28933576 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.64 0.34 1.26e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4319547 0.695 rs4758662 chr12:122924778 G/A cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.46 -0.37 7.12e-13 Body mass index; LIHC cis rs7131987 0.868 rs11050151 chr12:29403008 T/A cg16970926 chr12:29381810 FAR2 0.33 7.24 0.36 2.91e-12 QT interval; LIHC cis rs2243480 0.901 rs778687 chr7:65835819 G/A cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC cis rs3820500 0.543 rs1146297 chr1:117910682 A/G cg20383390 chr1:117909022 MAN1A2 -0.46 -5.97 -0.31 5.96e-9 Pneumonia; LIHC cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg01017244 chr2:74357527 NA 0.63 11.33 0.52 1.7e-25 Gestational age at birth (maternal effect); LIHC cis rs8017423 1.000 rs4900028 chr14:90685594 C/T cg04374321 chr14:90722782 PSMC1 0.72 13.74 0.6 1.62e-34 Mortality in heart failure; LIHC cis rs4474465 0.850 rs4945289 chr11:78245334 G/T cg27205649 chr11:78285834 NARS2 0.39 6.15 0.32 2.14e-9 Alzheimer's disease (survival time); LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.697 rs28655325 chr4:120372999 A/G cg25214090 chr10:38739885 LOC399744 0.6 9.73 0.47 6.32e-20 Corneal astigmatism; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15889976 chr12:124432796 CCDC92 -0.39 -6.52 -0.33 2.56e-10 Systolic blood pressure; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg00280220 chr17:61926910 NA 0.43 6.85 0.35 3.35e-11 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15688767 chr3:125093330 ZNF148 0.49 6.97 0.35 1.68e-11 Pancreatic cancer; LIHC cis rs10193935 0.901 rs6544529 chr2:42510652 A/T cg27598129 chr2:42591480 NA -0.7 -10.82 -0.51 1.14e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs4561483 0.582 rs35063476 chr16:12044301 A/G cg08843971 chr16:11963173 GSPT1 -0.32 -6.5 -0.33 2.91e-10 Testicular germ cell tumor; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17683632 chr2:210883371 RPE -0.27 -6.29 -0.32 9.85e-10 Calcium levels; LIHC cis rs9359856 0.564 rs72915903 chr6:90420190 A/C cg13799429 chr6:90582589 CASP8AP2 -0.68 -6.54 -0.33 2.21e-10 Bipolar disorder; LIHC cis rs4243830 0.850 rs4908910 chr1:6599362 T/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.84 -9.45 -0.46 5.47e-19 Body mass index; LIHC cis rs4631830 0.863 rs2843546 chr10:51518688 A/C cg20129853 chr10:51489980 NA -0.42 -9.16 -0.44 4.9e-18 Prostate-specific antigen levels; LIHC cis rs875971 0.660 rs79009421 chr7:66068509 G/C cg11764359 chr7:65958608 NA -0.72 -10.93 -0.51 4.85e-24 Aortic root size; LIHC cis rs3008870 0.755 rs11208974 chr1:67398119 A/T cg02640540 chr1:67518911 SLC35D1 0.41 6.38 0.33 5.76e-10 Lymphocyte percentage of white cells; LIHC cis rs9534288 0.797 rs9526127 chr13:46571744 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC trans rs1005277 0.579 rs1740749 chr10:38521646 A/G cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs9596863 0.898 rs9568901 chr13:54321748 A/C ch.13.53330881F chr13:54432880 NA 0.42 5.73 0.3 2.19e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs875971 0.508 rs10242423 chr7:66059175 A/G cg11764359 chr7:65958608 NA -0.63 -9.52 -0.46 3.25e-19 Aortic root size; LIHC cis rs751728 1.000 rs2296747 chr6:33744882 C/G cg25922239 chr6:33757077 LEMD2 0.43 7.18 0.36 4.29e-12 Crohn's disease; LIHC cis rs801193 0.548 rs7805152 chr7:66209253 C/T cg11764359 chr7:65958608 NA 0.75 12.68 0.57 1.77e-30 Aortic root size; LIHC cis rs2033711 0.840 rs10423138 chr19:58928302 T/C cg13877915 chr19:58951672 ZNF132 0.57 8.92 0.43 2.94e-17 Uric acid clearance; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 9.04e-33 Prudent dietary pattern; LIHC cis rs2070488 0.861 rs1858740 chr3:38438372 T/C cg24069376 chr3:38537580 EXOG 0.38 6.87 0.35 3.12e-11 Electrocardiographic conduction measures; LIHC cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg00166722 chr3:10149974 C3orf24 0.53 6.15 0.32 2.11e-9 Alzheimer's disease; LIHC cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg17971929 chr21:40555470 PSMG1 -0.52 -8.03 -0.4 1.56e-14 Cognitive function; LIHC cis rs10870270 0.956 rs11146325 chr10:133767529 A/G cg26149184 chr10:133730230 NA 0.47 7.49 0.38 5.75e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs3762637 1.000 rs28434553 chr3:122229515 C/A cg24169773 chr3:122142474 KPNA1 -0.45 -8.96 -0.44 2.12e-17 LDL cholesterol levels; LIHC cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg07424592 chr7:64974309 NA -0.79 -9.51 -0.46 3.47e-19 Diabetic kidney disease; LIHC cis rs709400 0.628 rs11621510 chr14:103869620 T/C cg26031613 chr14:104095156 KLC1 0.79 10.09 0.48 4.12e-21 Body mass index; LIHC cis rs9517320 0.534 rs9554474 chr13:99140871 G/A cg07423050 chr13:99094983 FARP1 -0.5 -8.97 -0.44 1.93e-17 Longevity; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg07133347 chr1:107600762 PRMT6 0.43 6.34 0.32 7.27e-10 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24023618 chr6:114292459 HDAC2 0.47 6.83 0.35 3.79e-11 Pancreatic cancer; LIHC cis rs62380364 0.542 rs601499 chr5:88052687 A/C cg22951263 chr5:87985283 NA -0.39 -6.84 -0.35 3.67e-11 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg03806693 chr22:41940476 POLR3H -1.07 -12.47 -0.56 1.15e-29 Vitiligo; LIHC cis rs8180040 0.932 rs1038394 chr3:47464122 A/G cg27129171 chr3:47204927 SETD2 0.57 9.83 0.47 3.11e-20 Colorectal cancer; LIHC cis rs2012796 1.000 rs12436146 chr14:81821282 A/G cg02996355 chr14:81879375 NA 0.45 6.79 0.34 5.04e-11 Night sleep phenotypes; LIHC cis rs1801251 0.893 rs6733151 chr2:233592341 A/C cg25237894 chr2:233734115 C2orf82 0.57 10.99 0.51 2.93e-24 Coronary artery disease; LIHC cis rs9325144 0.534 rs1843887 chr12:38692380 T/C cg26384229 chr12:38710491 ALG10B 0.6 8.38 0.41 1.35e-15 Morning vs. evening chronotype; LIHC cis rs3540 0.576 rs12907587 chr15:91045851 G/C cg22089800 chr15:90895588 ZNF774 -0.58 -8.09 -0.4 1.05e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs6542838 0.609 rs13028500 chr2:99528296 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -6.56 -0.33 2e-10 Fear of minor pain; LIHC cis rs8017423 0.605 rs3742673 chr14:90735707 C/T cg04374321 chr14:90722782 PSMC1 0.56 9.36 0.45 1.12e-18 Mortality in heart failure; LIHC cis rs13040088 1.000 rs13040088 chr20:61549202 A/G cg23096297 chr20:61557774 DIDO1 0.84 11.67 0.53 1.02e-26 Menopause (age at onset); LIHC cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg13271783 chr10:134563150 INPP5A 0.56 6.93 0.35 2.1e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7772486 0.875 rs1412080 chr6:146417304 T/C cg23711669 chr6:146136114 FBXO30 0.57 9.82 0.47 3.37e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs9393692 0.905 rs9366649 chr6:26329103 A/T cg05868516 chr6:26286170 HIST1H4H -0.38 -5.96 -0.31 6.29e-9 Educational attainment; LIHC cis rs2274273 0.870 rs10145203 chr14:55784458 A/C cg01864836 chr14:55583639 NA -0.37 -6.61 -0.34 1.49e-10 Protein biomarker; LIHC cis rs1551570 0.755 rs2290687 chr19:10229521 C/T cg16327482 chr19:10226339 EIF3G 0.49 8.58 0.42 3.26e-16 Narcolepsy; LIHC cis rs7577696 0.512 rs212736 chr2:32473126 T/C cg02381751 chr2:32503542 YIPF4 0.44 5.77 0.3 1.74e-8 Inflammatory biomarkers; LIHC cis rs10540 0.908 rs12792111 chr11:520921 G/C cg03352830 chr11:487213 PTDSS2 0.79 6.36 0.33 6.32e-10 Body mass index; LIHC cis rs1144333 0.655 rs76612182 chr1:76451889 C/T cg10523679 chr1:76189770 ACADM 0.45 6.09 0.31 3.08e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7248779 0.512 rs7250002 chr19:2413188 A/G cg22729335 chr19:2427816 TIMM13 1.1 23.27 0.78 1.82e-72 Cortisol levels (saliva); LIHC cis rs9640161 0.673 rs34489187 chr7:150044379 G/A cg27494647 chr7:150038898 RARRES2 0.35 6.45 0.33 3.85e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg00149659 chr3:10157352 C3orf10 0.6 6.55 0.33 2.17e-10 Alzheimer's disease; LIHC cis rs6570726 0.935 rs449377 chr6:145852437 C/G cg23711669 chr6:146136114 FBXO30 0.53 9.26 0.45 2.24e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs644799 0.710 rs522536 chr11:95528714 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.64 0.56 2.6e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9303401 0.921 rs34102441 chr17:56877414 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.43 6.33 0.32 7.81e-10 Cognitive test performance; LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs16828019 0.852 rs10489520 chr1:41511755 C/A cg03387723 chr1:41708464 SCMH1 -0.41 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.966 rs34630580 chr10:35449228 A/G cg04310649 chr10:35416472 CREM -0.42 -5.76 -0.3 1.91e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4803468 1.000 rs10417997 chr19:41902361 G/A cg09537434 chr19:41945824 ATP5SL -0.99 -20.64 -0.74 4.81e-62 Height; LIHC cis rs4589502 0.800 rs1498499 chr15:67202620 C/T cg09911534 chr15:67153556 NA 0.44 6.8 0.35 4.62e-11 Lung cancer (smoking interaction); LIHC cis rs589448 1.000 rs589448 chr12:69752200 A/G cg22834771 chr12:69754056 YEATS4 -0.54 -9.55 -0.46 2.62e-19 Cerebrospinal fluid biomarker levels; LIHC cis rs7953249 0.935 rs7135337 chr12:121404155 A/C cg02403541 chr12:121454288 C12orf43 -0.37 -6.32 -0.32 8.23e-10 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs1707322 1.000 rs4390216 chr1:46266456 C/T cg03146154 chr1:46216737 IPP 0.47 7.69 0.38 1.54e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4566357 0.539 rs10933164 chr2:227860671 A/G cg11843606 chr2:227700838 RHBDD1 -0.82 -9.1 -0.44 7.44e-18 Coronary artery disease; LIHC cis rs35110281 0.667 rs7282122 chr21:45082365 G/A cg21573476 chr21:45109991 RRP1B -0.57 -10.59 -0.5 7.54e-23 Mean corpuscular volume; LIHC cis rs11122272 0.735 rs2790886 chr1:231529491 A/C cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg00280220 chr17:61926910 NA 0.44 7.06 0.36 9.25e-12 Prudent dietary pattern; LIHC cis rs7927771 0.864 rs11600581 chr11:47448497 T/C cg20307385 chr11:47447363 PSMC3 -0.49 -6.29 -0.32 9.47e-10 Subjective well-being; LIHC cis rs17776563 1.000 rs11638818 chr15:89119711 C/T cg05013243 chr15:89149849 MIR1179 0.44 7.28 0.37 2.28e-12 Thyroid hormone levels; LIHC cis rs12701220 0.655 rs10241018 chr7:1144774 G/C cg04025307 chr7:1156635 C7orf50 0.53 6.92 0.35 2.22e-11 Bronchopulmonary dysplasia; LIHC cis rs34172651 0.917 rs200538 chr16:24735736 C/T cg00339695 chr16:24857497 SLC5A11 -0.32 -5.83 -0.3 1.31e-8 Intelligence (multi-trait analysis); LIHC cis rs4660306 0.614 rs1765711 chr1:45936285 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.63 6.92 0.35 2.19e-11 Homocysteine levels; LIHC trans rs1005277 0.579 rs2474574 chr10:38387295 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC trans rs7618501 1.000 rs7649348 chr3:49772375 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC cis rs4076764 0.830 rs10917770 chr1:163442214 G/C cg24596788 chr1:163392923 NA -0.24 -7.29 -0.37 2.2e-12 Motion sickness; LIHC cis rs7945705 0.869 rs2742471 chr11:9003953 C/T cg12365402 chr11:9010492 NRIP3 -0.33 -8.46 -0.42 7.72e-16 Hemoglobin concentration; LIHC cis rs1023500 0.956 rs1894713 chr22:42335621 G/A cg04733989 chr22:42467013 NAGA -0.51 -5.9 -0.3 8.82e-9 Schizophrenia; LIHC cis rs6594499 0.872 rs10043631 chr5:110443228 C/T cg04022379 chr5:110408740 TSLP 0.5 8.37 0.41 1.53e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs9399135 0.967 rs6925424 chr6:135313948 T/A cg22676075 chr6:135203613 NA 0.38 6.29 0.32 9.78e-10 Red blood cell count; LIHC cis rs7769051 1.000 rs58832890 chr6:133127139 C/T cg22852734 chr6:133119734 C6orf192 0.95 9.27 0.45 2.13e-18 Type 2 diabetes nephropathy; LIHC cis rs17021463 0.902 rs13102926 chr4:95245527 C/T cg11021082 chr4:95130006 SMARCAD1 0.47 8.58 0.42 3.27e-16 Testicular germ cell tumor; LIHC cis rs11190604 0.943 rs9420792 chr10:102258439 C/T cg07080220 chr10:102295463 HIF1AN 0.53 7.74 0.39 1.12e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg05552183 chr6:42928497 GNMT 0.67 10.06 0.48 4.99e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs367615 0.552 rs2963024 chr5:108730773 C/T cg17395555 chr5:108820864 NA -0.27 -5.88 -0.3 9.96e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs6754311 0.638 rs1011361 chr2:136553639 G/A cg07305463 chr2:136567211 LCT 0.4 7.39 0.37 1.1e-12 Mosquito bite size; LIHC trans rs9747201 0.962 rs6502062 chr17:80086177 T/G cg07393940 chr7:158741817 NA -0.55 -6.53 -0.33 2.35e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs344364 0.602 rs2437745 chr16:1908431 G/C cg00564555 chr16:1970112 NA 0.26 6.0 0.31 5.13e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg19318889 chr4:1322082 MAEA 0.49 6.77 0.34 5.73e-11 Obesity-related traits; LIHC cis rs2422052 0.614 rs13004599 chr2:118647505 G/A cg22545206 chr2:118617499 NA 0.36 6.08 0.31 3.25e-9 Mosquito bite size; LIHC cis rs2204008 0.522 rs117743143 chr12:38030824 C/T cg26384229 chr12:38710491 ALG10B 0.49 6.7 0.34 8.79e-11 Bladder cancer; LIHC trans rs11689435 0.925 rs17807893 chr2:218351373 A/C cg13544946 chr9:35729779 TLN1 -0.41 -6.1 -0.31 2.82e-9 Metabolite levels (MHPG); LIHC cis rs3782089 1.000 rs11602375 chr11:65296540 C/T cg21890820 chr11:65308645 LTBP3 0.93 6.55 0.33 2.08e-10 Height; LIHC cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg25072359 chr17:41440525 NA 0.41 6.44 0.33 4.14e-10 Menopause (age at onset); LIHC cis rs4773330 0.925 rs7331226 chr13:111814205 A/G cg26911804 chr13:111806221 ARHGEF7 0.61 6.02 0.31 4.54e-9 Bilirubin levels; LIHC cis rs12586317 0.514 rs74590021 chr14:35490113 T/G cg05294307 chr14:35346193 BAZ1A -0.49 -7.42 -0.37 9.63e-13 Psoriasis; LIHC cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg06481639 chr22:41940642 POLR3H -0.7 -6.94 -0.35 1.97e-11 Vitiligo; LIHC trans rs1474747 0.931 rs965358 chr1:159140349 A/T cg00587465 chr19:45429910 APOC1P1 0.34 6.08 0.31 3.24e-9 Select biomarker traits; LIHC cis rs311392 0.867 rs434952 chr8:55091998 C/T cg20636351 chr8:55087400 NA -0.38 -7.73 -0.39 1.2e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs2302190 1.000 rs7207286 chr17:56514458 A/C cg12560992 chr17:57184187 TRIM37 -0.71 -9.15 -0.44 5.07e-18 Vitamin D levels; LIHC cis rs7552404 0.727 rs1146653 chr1:76280438 A/G cg10523679 chr1:76189770 ACADM 0.56 7.01 0.35 1.26e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7098414 0.511 rs10466236 chr10:82149717 C/T cg01528321 chr10:82214614 TSPAN14 -0.42 -6.47 -0.33 3.31e-10 Post bronchodilator FEV1; LIHC cis rs2108622 0.727 rs12609900 chr19:15982414 G/A cg13772218 chr19:15982569 NA 0.37 7.8 0.39 7.46e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg09455208 chr3:40491958 NA 0.41 8.27 0.41 3.08e-15 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11388866 chr21:40752116 WRB -0.43 -6.4 -0.33 5.18e-10 Pancreatic cancer; LIHC cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg20399509 chr21:47717575 C21orf57 -0.4 -6.13 -0.31 2.39e-9 Testicular germ cell tumor; LIHC cis rs6429082 0.783 rs291385 chr1:235646613 T/C cg26050004 chr1:235667680 B3GALNT2 0.49 7.49 0.38 5.74e-13 Adiposity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17139369 chr19:8478169 MARCH2 0.49 6.39 0.33 5.43e-10 Lung function (FEV1/FVC); LIHC cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg20887711 chr4:1340912 KIAA1530 0.49 7.67 0.38 1.86e-13 Obesity-related traits; LIHC cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg05564831 chr3:52568323 NT5DC2 0.35 5.83 0.3 1.27e-8 Bipolar disorder; LIHC cis rs4927850 0.794 rs4927849 chr3:195738482 A/G cg01181863 chr3:195395398 SDHAP2 -0.9 -8.19 -0.4 5.32e-15 Pancreatic cancer; LIHC cis rs72781680 1.000 rs11553491 chr2:24225901 G/C cg08917208 chr2:24149416 ATAD2B 0.87 7.73 0.39 1.21e-13 Lymphocyte counts; LIHC cis rs4589502 0.841 rs56401320 chr15:67140517 C/G cg09911534 chr15:67153556 NA -0.46 -6.11 -0.31 2.7e-9 Lung cancer (smoking interaction); LIHC cis rs10489202 1.000 rs12407660 chr1:167954363 C/T cg24449463 chr1:168025552 DCAF6 -0.53 -6.72 -0.34 7.5e-11 Schizophrenia; LIHC trans rs983392 0.709 rs1820428 chr11:59986333 A/T cg17275991 chr19:58003312 ZNF419 0.44 6.27 0.32 1.08e-9 Alzheimer's disease (late onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01538984 chr7:140396422 LOC100134713;NDUFB2 0.45 6.59 0.34 1.63e-10 Pancreatic cancer; LIHC cis rs7211079 0.719 rs2289535 chr17:78111449 A/C cg09238746 chr17:78121135 EIF4A3 -0.5 -7.19 -0.36 4.21e-12 Myocardial infarction; LIHC trans rs75804782 0.641 rs77448526 chr2:239353487 A/C cg01134436 chr17:81009848 B3GNTL1 0.8 6.64 0.34 1.27e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg24531977 chr5:56204891 C5orf35 0.65 8.87 0.43 4.17e-17 Initial pursuit acceleration; LIHC cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs7131987 0.621 rs6487805 chr12:29457550 A/T cg12903224 chr12:29470962 FAR2 0.4 6.61 0.34 1.5e-10 QT interval; LIHC cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg09323728 chr8:95962352 TP53INP1 0.27 6.06 0.31 3.59e-9 Type 2 diabetes; LIHC cis rs3540 0.553 rs12592611 chr15:91004093 C/T cg22089800 chr15:90895588 ZNF774 0.58 8.01 0.4 1.8e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs4076764 0.914 rs6689760 chr1:163358704 A/G cg06092702 chr1:163392909 NA 0.2 5.89 0.3 9.09e-9 Motion sickness; LIHC cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.75 0.47 5.42e-20 Mean platelet volume; LIHC cis rs7618501 0.501 rs35275715 chr3:49959148 A/G cg21467203 chr3:49911342 NA -0.58 -10.66 -0.5 4.16e-23 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.627 rs7282704 chr21:44966253 A/G cg04455712 chr21:45112962 RRP1B 0.4 6.58 0.34 1.73e-10 Mean corpuscular volume; LIHC cis rs172166 0.652 rs476167 chr6:28065888 T/C cg23485639 chr6:28045615 ZNF165 0.39 6.05 0.31 3.78e-9 Cardiac Troponin-T levels; LIHC cis rs55702914 0.742 rs34555121 chr2:198166053 C/T cg03934865 chr2:198174659 NA 0.4 5.73 0.3 2.16e-8 Major depression and alcohol dependence; LIHC cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg22907277 chr7:1156413 C7orf50 0.44 6.32 0.32 7.94e-10 Longevity;Endometriosis; LIHC trans rs3780486 0.541 rs10738909 chr9:33148834 T/C cg04842962 chr6:43655489 MRPS18A 0.8 15.39 0.64 5.49e-41 IgG glycosylation; LIHC cis rs8064299 0.934 rs895692 chr17:72766252 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.68 11.6 0.53 1.82e-26 Monocyte count; LIHC cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg06481639 chr22:41940642 POLR3H 0.7 6.85 0.35 3.35e-11 Vitiligo; LIHC cis rs2576037 0.583 rs9960463 chr18:44522808 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 10.17 0.48 2.19e-21 Personality dimensions; LIHC cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg18306943 chr3:40428807 ENTPD3 -0.35 -6.16 -0.32 2.03e-9 Renal cell carcinoma; LIHC cis rs11671005 0.696 rs73066211 chr19:58997079 C/T cg25952890 chr19:58913133 NA 0.73 7.45 0.37 7.64e-13 Mean platelet volume; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05969148 chr19:51307846 C19orf48 -0.48 -6.2 -0.32 1.63e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs34172651 0.517 rs2547040 chr16:24736408 G/C cg04756594 chr16:24857601 SLC5A11 -0.56 -8.43 -0.41 9.7e-16 Intelligence (multi-trait analysis); LIHC cis rs17854409 0.764 rs73613593 chr20:61471582 T/C cg06598544 chr20:61472147 COL9A3 -0.91 -7.86 -0.39 4.97e-14 Obesity-related traits; LIHC cis rs72781680 0.821 rs2339887 chr2:24198376 G/A cg08917208 chr2:24149416 ATAD2B 0.62 6.25 0.32 1.25e-9 Lymphocyte counts; LIHC trans rs259842 0.800 rs6725456 chr2:180718419 C/T cg16168311 chr1:156561947 APOA1BP 0.41 6.49 0.33 2.99e-10 Blood protein levels; LIHC cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.616 rs10839388 chr11:49842603 C/T cg03929089 chr4:120376271 NA -0.84 -15.87 -0.65 6.88e-43 Height; LIHC cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.82e-13 Bipolar disorder; LIHC cis rs1003719 0.751 rs10154032 chr21:38453459 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 12.11 0.55 2.48e-28 Eye color traits; LIHC cis rs4820539 0.966 rs5751587 chr22:23470090 G/A cg21100191 chr22:23484243 RTDR1 0.92 17.13 0.68 6.07e-48 Bone mineral density; LIHC cis rs801193 1.000 rs7785213 chr7:66138978 A/C cg18876405 chr7:65276391 NA -0.43 -7.56 -0.38 3.83e-13 Aortic root size; LIHC trans rs7448169 1.000 rs7705200 chr5:99147531 C/G cg11015893 chr7:135433540 FAM180A 0.25 6.11 0.31 2.72e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs735860 0.718 rs209488 chr6:53177540 A/T cg10236188 chr6:53219634 NA 0.4 7.33 0.37 1.66e-12 Glaucoma; LIHC cis rs8072100 0.840 rs4968319 chr17:45464967 A/G cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.92 -0.3 7.9e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T ch.14.1056569F chr14:73577815 RBM25 -0.39 -6.47 -0.33 3.42e-10 Hepatitis; LIHC cis rs7587476 1.000 rs7587476 chr2:215653887 T/C cg04530015 chr2:215796436 ABCA12 0.41 6.53 0.33 2.32e-10 Neuroblastoma; LIHC cis rs72627509 0.904 rs781663 chr4:57781754 A/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.55 -7.99 -0.4 2.14e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9611565 0.694 rs5758389 chr22:41941749 T/C cg03806693 chr22:41940476 POLR3H -0.51 -6.8 -0.35 4.54e-11 Vitiligo; LIHC cis rs7605378 0.528 rs281767 chr2:200823281 C/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.54 7.27 0.37 2.51e-12 Osteoporosis; LIHC cis rs75064307 0.834 rs4855561 chr3:108116331 T/C cg03329597 chr3:108125523 MYH15 0.5 6.63 0.34 1.32e-10 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.962 rs11789624 chr9:111796231 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.45 0.42 8.3e-16 Menarche (age at onset); LIHC cis rs7408868 0.764 rs62113791 chr19:15277009 C/T cg14696996 chr19:15285081 NOTCH3 0.53 7.1 0.36 7.41e-12 Pulse pressure; LIHC cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg16049864 chr8:95962084 TP53INP1 0.58 11.21 0.52 4.79e-25 Type 2 diabetes; LIHC cis rs2549003 1.000 rs7701588 chr5:131819970 T/C cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.25e-20 Asthma (sex interaction); LIHC cis rs11098499 0.954 rs11098525 chr4:120390152 G/A cg09307838 chr4:120376055 NA 0.77 12.27 0.55 6.06e-29 Corneal astigmatism; LIHC cis rs262150 0.579 rs73167299 chr7:158784367 C/T cg13444538 chr7:158905317 VIPR2 -0.31 -5.77 -0.3 1.74e-8 Facial morphology (factor 20); LIHC trans rs116095464 0.558 rs62344300 chr5:246336 A/G cg00938859 chr5:1591904 SDHAP3 0.57 7.07 0.36 8.57e-12 Breast cancer; LIHC cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg03806693 chr22:41940476 POLR3H -1.14 -13.43 -0.59 2.64e-33 Vitiligo; LIHC cis rs4654899 0.758 rs9426652 chr1:21458151 G/A cg08539965 chr1:21396338 EIF4G3 0.32 5.72 0.3 2.27e-8 Superior frontal gyrus grey matter volume; LIHC trans rs62103177 0.673 rs36087369 chr18:77589596 C/G cg05926928 chr17:57297772 GDPD1 0.55 7.22 0.36 3.49e-12 Opioid sensitivity; LIHC cis rs875971 0.862 rs11765791 chr7:65936574 A/G cg18876405 chr7:65276391 NA 0.35 6.46 0.33 3.65e-10 Aortic root size; LIHC cis rs12048904 0.505 rs6577209 chr1:101255080 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.57 9.0 0.44 1.64e-17 Multiple sclerosis; LIHC cis rs910316 0.935 rs2268620 chr14:75640403 G/A cg11812906 chr14:75593930 NEK9 -0.72 -13.95 -0.6 2.61e-35 Height; LIHC cis rs72772090 1.000 rs72772095 chr5:96053853 T/C cg17330273 chr5:96107758 CAST;ERAP1 -0.6 -6.76 -0.34 5.9e-11 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12477438 0.520 rs2516830 chr2:99773702 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs11098499 0.954 rs6847248 chr4:120225955 A/G cg09307838 chr4:120376055 NA 0.73 10.8 0.5 1.33e-23 Corneal astigmatism; LIHC cis rs9303401 0.659 rs7223708 chr17:56896398 A/G cg25039879 chr17:56429692 SUPT4H1 0.77 8.91 0.43 3e-17 Cognitive test performance; LIHC cis rs700651 0.821 rs770661 chr2:198725444 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Intracranial aneurysm; LIHC cis rs4595586 0.546 rs10876163 chr12:39244915 G/A cg26384229 chr12:38710491 ALG10B 0.52 6.94 0.35 1.95e-11 Morning vs. evening chronotype; LIHC cis rs2230307 0.536 rs640030 chr1:100574992 C/T cg24955406 chr1:100503596 HIAT1 -0.6 -5.98 -0.31 5.59e-9 Carotid intima media thickness; LIHC cis rs10792665 0.724 rs11233398 chr11:82691952 A/G cg24227371 chr11:82718527 RAB30 -0.36 -8.68 -0.42 1.64e-16 Obesity-related traits; LIHC cis rs7666738 0.830 rs7687315 chr4:98900613 A/G cg05340658 chr4:99064831 C4orf37 0.65 11.81 0.54 3.25e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7927592 0.731 rs11228288 chr11:68353550 A/G cg01657329 chr11:68192670 LRP5 -0.5 -7.38 -0.37 1.19e-12 Total body bone mineral density; LIHC trans rs561341 1.000 rs546748 chr17:30324293 A/C cg20587970 chr11:113659929 NA -0.64 -7.41 -0.37 9.95e-13 Hip circumference adjusted for BMI; LIHC cis rs2836974 0.644 rs1882779 chr21:40690938 T/C cg11890956 chr21:40555474 PSMG1 -0.46 -7.36 -0.37 1.37e-12 Cognitive function; LIHC cis rs4803468 1.000 rs4803469 chr19:41922775 A/C cg09537434 chr19:41945824 ATP5SL -1.03 -21.78 -0.76 1.34e-66 Height; LIHC cis rs7534824 0.625 rs7514731 chr1:101449675 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 7.69 0.38 1.54e-13 Refractive astigmatism; LIHC cis rs4820294 0.669 rs9622677 chr22:38054262 A/C cg26138144 chr22:38071188 LGALS1 0.42 7.83 0.39 6.21e-14 Fat distribution (HIV); LIHC cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.6 8.88 0.43 3.86e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs8044995 0.563 rs61746794 chr16:68387457 C/T cg03983715 chr16:68378420 PRMT7 -0.51 -6.03 -0.31 4.27e-9 Schizophrenia; LIHC cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 9.92 0.47 1.54e-20 Platelet count; LIHC trans rs11098499 0.954 rs2389802 chr4:120325732 C/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs7116495 0.609 rs79889241 chr11:71815585 T/C cg26138937 chr11:71823887 C11orf51 1.34 10.79 0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC cis rs8108269 1.000 rs7258890 chr19:46159609 T/C cg13320842 chr19:46175254 GIPR 0.41 7.7 0.38 1.5e-13 Type 2 diabetes; LIHC cis rs35110281 0.720 rs162376 chr21:44926759 G/T cg04455712 chr21:45112962 RRP1B -0.47 -7.61 -0.38 2.71e-13 Mean corpuscular volume; LIHC cis rs8180040 0.966 rs13079098 chr3:47442863 A/G cg16586182 chr3:47516702 SCAP -0.59 -11.48 -0.53 5.15e-26 Colorectal cancer; LIHC cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.6 0.56 3.6e-30 Alzheimer's disease; LIHC cis rs7615952 0.800 rs35390120 chr3:125599809 G/A cg05084668 chr3:125655381 ALG1L -0.8 -10.87 -0.51 8.03e-24 Blood pressure (smoking interaction); LIHC cis rs7772486 0.806 rs2265477 chr6:146212338 T/C cg05347473 chr6:146136440 FBXO30 0.36 6.0 0.31 4.95e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17427986 chr1:154402922 IL6R -0.42 -6.4 -0.33 5.01e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7246657 0.943 rs10417844 chr19:37837587 C/T cg23950597 chr19:37808831 NA -0.44 -5.97 -0.31 5.93e-9 Coronary artery calcification; LIHC cis rs7945718 0.870 rs3890064 chr11:12758766 C/A cg25843174 chr11:12811716 TEAD1 0.33 7.39 0.37 1.12e-12 Educational attainment (years of education); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18115022 chr15:65822705 PTPLAD1 -0.54 -7.1 -0.36 7.41e-12 Systolic blood pressure; LIHC trans rs1814175 0.588 rs10466497 chr11:49864381 A/T cg03929089 chr4:120376271 NA -0.83 -15.94 -0.65 3.68e-43 Height; LIHC cis rs7937890 0.559 rs2034480 chr11:14466923 G/A cg02886208 chr11:14281011 SPON1 -0.46 -6.46 -0.33 3.58e-10 Mitochondrial DNA levels; LIHC cis rs12431939 1.000 rs4567626 chr14:51647640 A/T cg23942311 chr14:51606299 NA 0.35 5.9 0.3 8.75e-9 Cancer; LIHC cis rs9457247 0.715 rs6923582 chr6:167437162 T/A cg12798992 chr6:167411361 FGFR1OP 0.5 7.61 0.38 2.69e-13 Crohn's disease; LIHC cis rs2952156 0.959 rs11653998 chr17:37877447 C/G cg00129232 chr17:37814104 STARD3 -0.5 -9.21 -0.45 3.47e-18 Asthma; LIHC cis rs34245846 0.704 rs11264278 chr1:154845534 G/C cg03351412 chr1:154909251 PMVK -0.58 -7.1 -0.36 7.47e-12 Atrial fibrillation; LIHC cis rs9399137 0.507 rs11754021 chr6:135308375 A/G cg24558204 chr6:135376177 HBS1L 0.6 10.38 0.49 4.14e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs4803468 1.000 rs2241709 chr19:41912250 C/T cg09537434 chr19:41945824 ATP5SL -1.01 -20.97 -0.75 2.29e-63 Height; LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg26338869 chr17:61819248 STRADA 0.52 6.91 0.35 2.33e-11 Height; LIHC cis rs1552244 0.882 rs13100734 chr3:10022878 A/G cg08888203 chr3:10149979 C3orf24 0.44 5.8 0.3 1.48e-8 Alzheimer's disease; LIHC cis rs6502050 0.835 rs4499294 chr17:80148346 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.78 -0.3 1.64e-8 Life satisfaction; LIHC cis rs3096299 0.582 rs12935119 chr16:89542874 A/T cg08392591 chr16:89556376 ANKRD11 0.4 6.17 0.32 1.94e-9 Multiple myeloma (IgH translocation); LIHC cis rs6701037 0.625 rs34270511 chr1:175128543 C/T cg00321850 chr1:175162397 KIAA0040 -0.43 -6.89 -0.35 2.77e-11 Alcohol dependence; LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg23131131 chr22:24373011 LOC391322 -0.62 -9.07 -0.44 9.26e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs55702914 1.000 rs55702914 chr2:198214396 C/G cg10820045 chr2:198174542 NA 0.38 5.83 0.3 1.31e-8 Major depression and alcohol dependence; LIHC cis rs782590 0.537 rs7575170 chr2:55886780 C/T cg03859395 chr2:55845619 SMEK2 -0.48 -7.69 -0.38 1.56e-13 Metabolic syndrome; LIHC cis rs17401966 0.898 rs12117635 chr1:10317445 C/T cg19773385 chr1:10388646 KIF1B -0.4 -7.28 -0.37 2.27e-12 Hepatocellular carcinoma; LIHC cis rs11971779 0.793 rs11772447 chr7:139033589 T/G cg07862535 chr7:139043722 LUC7L2 0.66 11.27 0.52 2.97e-25 Diisocyanate-induced asthma; LIHC cis rs2455799 0.634 rs6771390 chr3:15906637 C/G cg12698662 chr3:15914712 MIR563 -0.4 -7.51 -0.38 5.11e-13 Mean platelet volume; LIHC cis rs7317038 1.000 rs7317038 chr13:114012898 C/T cg24344662 chr13:114018021 GRTP1 -0.44 -6.59 -0.34 1.65e-10 Mean platelet volume; LIHC cis rs7914558 0.966 rs11191438 chr10:104637864 C/G cg04362960 chr10:104952993 NT5C2 0.39 5.86 0.3 1.08e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4665809 1.000 rs10048648 chr2:26320315 T/C cg27170947 chr2:26402098 FAM59B -0.61 -7.73 -0.39 1.22e-13 Gut microbiome composition (summer); LIHC cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg17554472 chr22:41940697 POLR3H 0.53 5.81 0.3 1.44e-8 Vitiligo; LIHC cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg06634786 chr22:41940651 POLR3H 0.79 9.1 0.44 7.43e-18 Vitiligo; LIHC cis rs1023500 0.551 rs2859438 chr22:42466980 A/T cg04733989 chr22:42467013 NAGA 0.67 9.79 0.47 4.03e-20 Schizophrenia; LIHC cis rs826838 0.967 rs7136593 chr12:39128265 C/T cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs2153535 0.601 rs2015281 chr6:8539673 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.66 0.42 1.89e-16 Motion sickness; LIHC cis rs2404602 0.647 rs11631394 chr15:76973209 G/T cg23625390 chr15:77176239 SCAPER -0.56 -9.5 -0.46 3.79e-19 Blood metabolite levels; LIHC cis rs56804039 1.000 rs17616779 chr8:8382374 A/G cg06636001 chr8:8085503 FLJ10661 0.53 7.25 0.37 2.71e-12 Cervical cancer; LIHC cis rs6466055 0.669 rs10953468 chr7:104741842 A/T cg04380332 chr7:105027541 SRPK2 -0.34 -6.32 -0.32 8.37e-10 Schizophrenia; LIHC cis rs6762477 0.748 rs2073726 chr3:50223593 T/A cg21467203 chr3:49911342 NA 0.37 6.44 0.33 4.06e-10 Menarche (age at onset); LIHC cis rs2932538 0.583 rs2932537 chr1:113230394 C/T cg22162597 chr1:113214053 CAPZA1 0.64 7.97 0.4 2.34e-14 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg26818010 chr10:134567672 INPP5A -0.77 -9.45 -0.46 5.46e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1904096 0.506 rs28701470 chr4:95167088 A/C cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.23 -0.45 2.99e-18 Type 2 diabetes; LIHC cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg07061783 chr6:25882402 NA 0.47 6.63 0.34 1.34e-10 Blood metabolite levels; LIHC cis rs262150 0.842 rs2657398 chr7:158784911 T/C cg19418458 chr7:158789849 NA -0.38 -6.51 -0.33 2.65e-10 Facial morphology (factor 20); LIHC cis rs7131987 0.622 rs7294598 chr12:29531989 A/C cg16970926 chr12:29381810 FAR2 -0.3 -6.38 -0.33 5.78e-10 QT interval; LIHC trans rs3780486 1.000 rs3780486 chr9:33139453 C/T cg04842962 chr6:43655489 MRPS18A 0.96 17.25 0.68 2.07e-48 IgG glycosylation; LIHC cis rs2816062 0.813 rs2745318 chr1:18895844 C/T cg18795169 chr1:18902165 NA 0.8 18.18 0.7 3.59e-52 Urate levels in lean individuals; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26446827 chr20:18268978 ZNF133 -0.49 -6.19 -0.32 1.73e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7487075 0.619 rs9669404 chr12:46798963 A/G cg23829395 chr12:46796953 NA -0.35 -6.25 -0.32 1.25e-9 Itch intensity from mosquito bite; LIHC cis rs2153535 0.580 rs2327067 chr6:8518482 C/G cg23788917 chr6:8435910 SLC35B3 0.61 8.68 0.42 1.64e-16 Motion sickness; LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.56 -8.07 -0.4 1.24e-14 Lymphocyte counts; LIHC cis rs55665837 0.502 rs4757269 chr11:14836192 A/C cg25251204 chr11:14927456 NA 0.42 6.03 0.31 4.32e-9 Vitamin D levels; LIHC cis rs4141404 0.923 rs2413035 chr22:31600460 A/G cg22777020 chr22:31556080 RNF185 -0.52 -5.84 -0.3 1.21e-8 Paclitaxel-induced neuropathy; LIHC cis rs11190604 0.767 rs11190509 chr10:102156208 G/A cg07080220 chr10:102295463 HIF1AN 0.45 5.98 0.31 5.5e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9297145 1.000 rs9297145 chr7:98759117 A/C cg05967295 chr7:98741636 SMURF1 0.66 10.51 0.49 1.4e-22 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs1371867 0.846 rs2047249 chr8:101234126 A/G cg06636551 chr8:101224915 SPAG1 0.46 8.72 0.43 1.24e-16 Atrioventricular conduction; LIHC cis rs8064024 0.582 rs2660241 chr16:4940023 T/C cg08329684 chr16:4932620 PPL 0.34 5.88 0.3 1e-8 Cancer; LIHC cis rs597539 0.652 rs686877 chr11:68637169 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.08e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs79057730 0.599 rs6944167 chr7:826274 G/C cg06242242 chr7:766104 PRKAR1B;HEATR2 0.75 8.37 0.41 1.53e-15 Initial pursuit acceleration; LIHC cis rs243505 0.691 rs243480 chr7:148452905 G/T cg09806900 chr7:148480153 CUL1 -0.43 -6.09 -0.31 3.01e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6762 0.719 rs4895 chr11:840477 A/G cg15787769 chr11:842744 TSPAN4;POLR2L -0.67 -8.08 -0.4 1.14e-14 Mean platelet volume; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.87 0.78 6.99e-71 Height; LIHC cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg03517284 chr6:25882590 NA 0.58 6.98 0.35 1.56e-11 Intelligence (multi-trait analysis); LIHC cis rs2455799 0.573 rs2470523 chr3:15768091 G/C cg12698662 chr3:15914712 MIR563 -0.39 -7.16 -0.36 5.03e-12 Mean platelet volume; LIHC cis rs75920871 0.557 rs7123336 chr11:116782819 T/C cg01368799 chr11:117014884 PAFAH1B2 -0.46 -5.93 -0.31 7.23e-9 Subjective well-being; LIHC cis rs344364 0.552 rs388928 chr16:1909657 G/C cg00564555 chr16:1970112 NA 0.27 6.29 0.32 9.59e-10 Glomerular filtration rate in chronic kidney disease; LIHC cis rs9911578 0.740 rs368243 chr17:56708979 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.57 8.03 0.4 1.57e-14 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.899 rs1562309 chr2:61770126 C/A cg14146966 chr2:61757674 XPO1 0.48 8.28 0.41 2.73e-15 Tuberculosis; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02951695 chr10:134400351 INPP5A 0.47 6.16 0.32 2.04e-9 Hepatitis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11933116 chr6:139349681 C6orf115 0.37 6.43 0.33 4.2e-10 Cognitive function; LIHC cis rs8078723 1.000 rs8070454 chr17:38160754 C/T cg17467752 chr17:38218738 THRA 0.76 13.98 0.6 1.96e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs11098499 0.909 rs1546502 chr4:120235898 A/G cg25214090 chr10:38739885 LOC399744 0.58 9.25 0.45 2.47e-18 Corneal astigmatism; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.7 0.38 1.51e-13 Height; LIHC cis rs4268898 0.662 rs58971404 chr2:24403753 G/A cg06627628 chr2:24431161 ITSN2 -0.69 -8.98 -0.44 1.9e-17 Asthma; LIHC cis rs7927592 0.763 rs7120876 chr11:68261398 C/G cg01657329 chr11:68192670 LRP5 -0.5 -7.27 -0.37 2.5e-12 Total body bone mineral density; LIHC cis rs3806843 0.966 rs11958868 chr5:140201420 T/C cg26395211 chr5:140044315 WDR55 -0.42 -6.25 -0.32 1.22e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9814567 0.806 rs1880375 chr3:134322163 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs782590 0.517 rs13013133 chr2:55889466 G/A cg18811423 chr2:55921094 PNPT1 -0.5 -7.16 -0.36 4.84e-12 Metabolic syndrome; LIHC cis rs6570726 0.791 rs9373466 chr6:145912016 T/C cg23711669 chr6:146136114 FBXO30 0.7 11.65 0.53 1.22e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08377569 chr16:30538014 ZNF768 0.45 6.52 0.33 2.46e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs9379206 chr6:8458021 C/A cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs9473924 0.505 rs4111288 chr6:50908094 G/A cg14470998 chr6:50812995 TFAP2B 0.91 10.51 0.49 1.39e-22 Body mass index; LIHC cis rs9611565 0.506 rs7364221 chr22:41650190 C/A cg03806693 chr22:41940476 POLR3H -0.65 -7.66 -0.38 1.99e-13 Vitiligo; LIHC cis rs7772486 0.790 rs2253764 chr6:146199881 T/A cg05347473 chr6:146136440 FBXO30 0.36 5.93 0.31 7.39e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs738322 0.967 rs132985 chr22:38563471 C/T cg17652424 chr22:38574118 PLA2G6 -0.19 -5.92 -0.3 7.95e-9 Cutaneous nevi; LIHC cis rs3762637 1.000 rs3762637 chr3:122145324 C/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC trans rs7226229 0.950 rs2291037 chr17:20924523 C/T ch.21.43742285F chr21:44917857 NA -0.41 -6.06 -0.31 3.69e-9 Blood trace element (Se levels); LIHC cis rs8067545 0.611 rs2703777 chr17:20138891 C/T cg13482628 chr17:19912719 NA -0.42 -6.9 -0.35 2.45e-11 Schizophrenia; LIHC cis rs2549003 0.966 rs2070730 chr5:131819800 G/A cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.25e-20 Asthma (sex interaction); LIHC cis rs477692 0.569 rs10764886 chr10:131310680 C/T cg05714579 chr10:131428358 MGMT 0.41 6.62 0.34 1.42e-10 Response to temozolomide; LIHC cis rs8081395 0.576 rs1292032 chr17:57992343 A/C cg13753209 chr17:57696993 CLTC 0.38 5.9 0.3 8.64e-9 White blood cell count; LIHC cis rs11190604 0.943 rs7900678 chr10:102229016 T/C cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs5758659 0.716 rs2143138 chr22:42618340 T/C cg19513890 chr22:42538836 CYP2D7P1 -0.31 -5.89 -0.3 9.41e-9 Cognitive function; LIHC cis rs7100689 0.646 rs1934692 chr10:82125734 C/A cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs61990749 0.597 rs717683 chr14:78255453 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.14 0.48 2.63e-21 Fibroblast growth factor basic levels; LIHC trans rs8002861 0.664 rs1466005 chr13:44424210 T/C cg17145862 chr1:211918768 LPGAT1 0.5 9.27 0.45 2.17e-18 Leprosy; LIHC cis rs9611565 0.592 rs5751129 chr22:42015765 C/T cg06634786 chr22:41940651 POLR3H 0.55 6.11 0.31 2.76e-9 Vitiligo; LIHC cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg18252515 chr7:66147081 NA -1.26 -16.63 -0.67 6.04e-46 Diabetic kidney disease; LIHC cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg21724239 chr8:58056113 NA 0.49 6.38 0.33 5.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs9549367 0.724 rs7985335 chr13:113869244 G/T cg18105134 chr13:113819100 PROZ 0.55 9.94 0.47 1.24e-20 Platelet distribution width; LIHC cis rs9303401 0.659 rs36109237 chr17:56653834 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs9916302 0.904 rs6503503 chr17:37514373 G/A cg07936489 chr17:37558343 FBXL20 0.81 12.96 0.57 1.6e-31 Glomerular filtration rate (creatinine); LIHC cis rs8017423 0.935 rs8012303 chr14:90715829 G/A cg04374321 chr14:90722782 PSMC1 0.74 14.57 0.62 9.4e-38 Mortality in heart failure; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07466437 chr6:8086756 EEF1E1;SCARNA27 0.4 6.41 0.33 4.86e-10 Longevity; LIHC cis rs6545883 0.929 rs7561229 chr2:61737990 A/T cg14146966 chr2:61757674 XPO1 0.49 8.82 0.43 5.82e-17 Tuberculosis; LIHC cis rs1552244 0.882 rs3846168 chr3:9996925 C/T cg00149659 chr3:10157352 C3orf10 0.5 5.75 0.3 1.96e-8 Alzheimer's disease; LIHC cis rs2635047 0.699 rs2247578 chr18:44745056 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.43 5.87 0.3 1.01e-8 Educational attainment; LIHC cis rs10744422 1.000 rs10744422 chr12:123336789 T/C cg18912006 chr12:123335444 HIP1R -0.64 -7.68 -0.38 1.69e-13 Schizophrenia; LIHC cis rs6570726 0.791 rs6923074 chr6:145893332 T/C cg05347473 chr6:146136440 FBXO30 0.39 6.24 0.32 1.32e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11608355 0.515 rs7136048 chr12:109903926 A/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs1801251 1.000 rs283479 chr2:233648754 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.04 0.51 1.86e-24 Coronary artery disease; LIHC cis rs10174077 0.687 rs4664491 chr2:152479986 C/T cg06191203 chr2:152266755 RIF1 -0.41 -6.89 -0.35 2.69e-11 Squamous cell lung carcinoma; LIHC trans rs2727020 0.617 rs7102702 chr11:49401125 T/G cg18944383 chr4:111397179 ENPEP 0.31 7.27 0.37 2.46e-12 Coronary artery disease; LIHC cis rs67981189 0.555 rs11623266 chr14:71365940 A/T cg15816911 chr14:71606274 NA -0.42 -6.72 -0.34 7.84e-11 Schizophrenia; LIHC cis rs4638749 0.677 rs13023102 chr2:108837663 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs8014671 0.553 rs34866539 chr14:70873763 T/C cg25576086 chr14:70833871 SYNJ2BP -0.45 -7.09 -0.36 7.65e-12 Prostate cancer; LIHC cis rs9910055 0.509 rs9916444 chr17:42313512 C/G cg08499158 chr17:42289980 UBTF -0.49 -7.98 -0.4 2.21e-14 Total body bone mineral density; LIHC cis rs9486715 0.790 rs2971602 chr6:97022468 C/T cg06623918 chr6:96969491 KIAA0776 -0.87 -15.36 -0.64 7.28e-41 Headache; LIHC trans rs6058796 0.901 rs6087966 chr20:31255035 C/G cg02600331 chr11:130417168 NA 0.35 7.6 0.38 2.82e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs6582630 0.519 rs7294292 chr12:38349540 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.28 0.41 2.76e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs12744310 0.887 rs12757611 chr1:41808972 C/T cg03387723 chr1:41708464 SCMH1 -0.33 -6.06 -0.31 3.66e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7216064 1.000 rs55939964 chr17:65869297 G/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs12478296 1.000 rs4973685 chr2:243019089 A/C cg01596870 chr19:55963115 NA -0.63 -7.51 -0.38 5.05e-13 Obesity-related traits; LIHC cis rs992157 0.717 rs3817266 chr2:219142594 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.12 -0.55 2.19e-28 Colorectal cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg13551243 chr8:146052742 ZNF7 -0.41 -6.26 -0.32 1.16e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs365132 0.905 rs353463 chr5:176403170 A/C cg16309518 chr5:176445507 NA -0.53 -10.06 -0.48 5.09e-21 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs2762353 0.603 rs4145221 chr6:25763192 A/G cg12310025 chr6:25882481 NA 0.48 6.51 0.33 2.66e-10 Blood metabolite levels; LIHC cis rs3768617 0.510 rs3818417 chr1:183079376 G/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.66 0.5 4.09e-23 Fuchs's corneal dystrophy; LIHC cis rs898097 0.801 rs68141193 chr17:80878816 C/T cg15369054 chr17:80825471 TBCD 0.42 6.03 0.31 4.36e-9 Breast cancer; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg15382696 chr6:118971807 C6orf204 0.62 6.45 0.33 3.75e-10 Diastolic blood pressure; LIHC cis rs35110281 0.782 rs4818856 chr21:45043495 A/G cg04455712 chr21:45112962 RRP1B 0.47 7.85 0.39 5.34e-14 Mean corpuscular volume; LIHC cis rs611744 0.839 rs672552 chr8:109164223 A/G cg21045802 chr8:109455806 TTC35 0.57 9.86 0.47 2.31e-20 Dupuytren's disease; LIHC cis rs7208859 0.623 rs56812022 chr17:29068733 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.52 0.53 3.63e-26 Alzheimer's disease; LIHC cis rs67478160 0.643 rs12891175 chr14:104274166 T/C cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.48 -0.37 6.33e-13 Schizophrenia; LIHC cis rs61990749 0.597 rs12887282 chr14:78200585 C/A cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.81 -0.39 7.3e-14 Fibroblast growth factor basic levels; LIHC cis rs700651 0.789 rs1813106 chr2:198880589 A/G cg10820045 chr2:198174542 NA 0.43 6.55 0.33 2.16e-10 Intracranial aneurysm; LIHC cis rs8067545 0.611 rs8071274 chr17:20216928 T/C cg13482628 chr17:19912719 NA -0.42 -6.86 -0.35 3.19e-11 Schizophrenia; LIHC cis rs2576037 0.583 rs478820 chr18:44397782 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.86 0.51 8.19e-24 Personality dimensions; LIHC cis rs9581857 1.000 rs9581857 chr13:28027714 A/C cg22138327 chr13:27999177 GTF3A 0.7 6.12 0.31 2.55e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11792649 chr11:68664631 MRPL21 0.43 6.55 0.33 2.14e-10 Bilirubin levels; LIHC cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs17376456 0.825 rs56108532 chr5:93276342 C/T cg25358565 chr5:93447407 FAM172A 1.1 10.25 0.48 1.15e-21 Diabetic retinopathy; LIHC cis rs7903847 0.642 rs1537645 chr10:99149914 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.34 -0.32 7.38e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10416265 0.527 rs7246814 chr19:33538414 G/T cg17764715 chr19:33622953 WDR88 0.55 7.48 0.38 6.21e-13 Bone properties (heel); LIHC cis rs10791097 0.720 rs6590518 chr11:130733530 C/T cg22079354 chr11:130786696 SNX19 0.42 6.11 0.31 2.78e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7772486 0.654 rs6906402 chr6:146089307 C/G cg13319975 chr6:146136371 FBXO30 0.41 6.66 0.34 1.08e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7520050 0.966 rs61783220 chr1:46335312 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2412488 0.850 rs6828559 chr4:54235363 A/C cg22241045 chr4:54363911 LNX1 -0.37 -5.93 -0.31 7.4e-9 DNA methylation (variation); LIHC cis rs16944613 0.510 rs17180057 chr15:91155834 G/A cg26821196 chr15:91095069 CRTC3 0.35 6.23 0.32 1.34e-9 Colorectal cancer; LIHC cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg21724239 chr8:58056113 NA 0.64 7.34 0.37 1.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs7635838 0.617 rs2122031 chr3:11314143 G/A cg00170343 chr3:11313890 ATG7 0.62 10.53 0.49 1.21e-22 HDL cholesterol; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg27247225 chr6:26970382 C6orf41 0.47 6.31 0.32 8.42e-10 Hepatitis; LIHC cis rs1707322 0.721 rs28442079 chr1:46172001 A/G cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7927592 0.956 rs55816191 chr11:68262979 G/T cg01657329 chr11:68192670 LRP5 -0.46 -6.12 -0.31 2.57e-9 Total body bone mineral density; LIHC cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg18252515 chr7:66147081 NA 1.27 16.79 0.67 1.38e-46 Diabetic kidney disease; LIHC cis rs4700695 0.841 rs251294 chr5:65261848 A/G cg21114390 chr5:65439923 SFRS12 0.44 5.75 0.3 1.94e-8 Facial morphology (factor 19); LIHC cis rs7572733 0.555 rs7561950 chr2:198754244 C/T cg10820045 chr2:198174542 NA 0.46 6.92 0.35 2.24e-11 Dermatomyositis; LIHC cis rs2439831 0.681 rs2444036 chr15:43694108 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.88 15.73 0.65 2.44e-42 Lung cancer in ever smokers; LIHC cis rs12701220 0.725 rs13242971 chr7:1055515 C/T cg16145915 chr7:1198662 ZFAND2A -0.3 -5.75 -0.3 1.93e-8 Bronchopulmonary dysplasia; LIHC cis rs11690935 0.851 rs9808259 chr2:172648974 C/T cg13550731 chr2:172543902 DYNC1I2 -0.94 -18.14 -0.7 5.44e-52 Schizophrenia; LIHC cis rs782590 0.837 rs809732 chr2:55914621 T/C cg18811423 chr2:55921094 PNPT1 0.94 15.33 0.64 9.51e-41 Metabolic syndrome; LIHC cis rs11122272 0.705 rs2491411 chr1:231533448 C/G cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.73e-19 Hemoglobin concentration; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05735659 chr12:48099394 RPAP3 -0.4 -6.33 -0.32 7.64e-10 Calcium levels; LIHC cis rs1144333 1.000 rs17097841 chr1:76462641 T/A cg03433033 chr1:76189801 ACADM 0.51 7.48 0.38 6.2800000000000005e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs12478296 0.685 rs12473450 chr2:242991746 C/T cg06360820 chr2:242988706 NA -0.8 -12.4 -0.56 2.06e-29 Obesity-related traits; LIHC trans rs7874142 0.616 rs4072883 chr9:137686906 C/T cg18109838 chr5:88185987 MEF2C -0.36 -7.14 -0.36 5.56e-12 Longevity; LIHC cis rs2762353 0.603 rs10946798 chr6:25781853 T/G cg03264133 chr6:25882463 NA 0.47 6.35 0.32 6.75e-10 Blood metabolite levels; LIHC cis rs2075371 0.966 rs2544223 chr7:133995787 A/G cg20476274 chr7:133979776 SLC35B4 0.74 12.24 0.55 7.96e-29 Mean platelet volume; LIHC cis rs2637030 0.559 rs256087 chr5:52895233 G/A cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.24e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs2576037 0.583 rs9304336 chr18:44461687 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 11.01 0.51 2.5e-24 Personality dimensions; LIHC cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg05564831 chr3:52568323 NT5DC2 0.35 5.87 0.3 1e-8 Bipolar disorder; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg12538369 chr19:40932019 SERTAD1 0.37 6.04 0.31 4.12e-9 Alopecia areata; LIHC cis rs10911363 0.592 rs2702180 chr1:183517971 T/C cg09173681 chr1:183549694 NCF2 0.54 9.56 0.46 2.32e-19 Systemic lupus erythematosus; LIHC cis rs7818382 1.000 rs7818382 chr8:96054000 C/T cg13393036 chr8:95962371 TP53INP1 -0.32 -7.14 -0.36 5.69e-12 Alzheimer's disease (late onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09997638 chr19:17530742 FAM125A -0.47 -7.02 -0.35 1.22e-11 Cognitive function; LIHC trans rs79387448 0.626 rs80277428 chr2:103080056 G/A cg06832677 chr2:119976764 NA 0.56 6.18 0.32 1.8e-9 Gut microbiota (bacterial taxa); LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg18538332 chr22:24372958 LOC391322 0.65 9.29 0.45 1.82e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs763121 0.853 rs1056610 chr22:39080078 C/T cg21395723 chr22:39101663 GTPBP1 -0.42 -7.3 -0.37 2.03e-12 Menopause (age at onset); LIHC cis rs17125944 0.505 rs2295827 chr14:53174981 C/T cg13660082 chr14:53194042 PSMC6 -0.47 -7.7 -0.38 1.49e-13 Alzheimer's disease (late onset); LIHC cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg03806693 chr22:41940476 POLR3H 1.09 12.91 0.57 2.49e-31 Vitiligo; LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg05025164 chr4:1340916 KIAA1530 0.8 12.76 0.57 8.91e-31 Longevity; LIHC cis rs6964587 0.626 rs35849169 chr7:91507313 A/G cg17063962 chr7:91808500 NA 0.62 11.08 0.51 1.43e-24 Breast cancer; LIHC cis rs72843506 0.656 rs78408002 chr17:19985914 A/G cg12065943 chr17:19881925 AKAP10 -0.33 -5.76 -0.3 1.9e-8 Schizophrenia; LIHC cis rs2204008 0.628 rs10876106 chr12:37990767 A/G cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC cis rs10193935 0.901 rs222478 chr2:42656919 G/T cg27598129 chr2:42591480 NA -0.73 -10.69 -0.5 3.32e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs11098499 0.754 rs878372 chr4:120238780 A/C cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.06e-25 Corneal astigmatism; LIHC cis rs11971779 0.715 rs55714903 chr7:139074590 T/C cg07862535 chr7:139043722 LUC7L2 0.64 11.08 0.51 1.44e-24 Diisocyanate-induced asthma; LIHC cis rs2549003 1.000 rs6873426 chr5:131818631 G/T cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.25e-20 Asthma (sex interaction); LIHC cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.49e-11 Diabetic kidney disease; LIHC cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg11890956 chr21:40555474 PSMG1 -0.52 -8.48 -0.42 7.01e-16 Cognitive function; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg20607798 chr8:58055168 NA 0.62 7.87 0.39 4.63e-14 Developmental language disorder (linguistic errors); LIHC cis rs1538970 0.816 rs12029322 chr1:45970446 C/T cg24296786 chr1:45957014 TESK2 -0.51 -7.54 -0.38 4.36e-13 Platelet count; LIHC trans rs1005277 0.683 rs7923868 chr10:37989766 T/C cg17830980 chr10:43048298 ZNF37B -0.41 -7.66 -0.38 1.93e-13 Extrinsic epigenetic age acceleration; LIHC cis rs4642101 0.618 rs7612317 chr3:12820558 C/T cg24848339 chr3:12840334 CAND2 0.31 6.43 0.33 4.17e-10 QRS complex (12-leadsum); LIHC cis rs3008870 1.000 rs2815348 chr1:67472165 G/C cg02640540 chr1:67518911 SLC35D1 0.44 6.06 0.31 3.5e-9 Lymphocyte percentage of white cells; LIHC cis rs7927592 0.913 rs3758643 chr11:68367193 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.24 -0.32 1.27e-9 Total body bone mineral density; LIHC cis rs9303280 0.806 rs10445308 chr17:37938047 C/T cg11212589 chr17:38028394 ZPBP2 0.32 6.44 0.33 4.06e-10 Self-reported allergy; LIHC cis rs875971 1.000 rs2420168 chr7:65630631 C/G cg18876405 chr7:65276391 NA -0.38 -6.88 -0.35 2.82e-11 Aortic root size; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.51 0.62 1.6e-37 Prudent dietary pattern; LIHC cis rs1552244 0.882 rs112621205 chr3:10017916 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs425277 0.628 rs3107145 chr1:2047547 G/A cg04315214 chr1:2043799 PRKCZ 0.42 6.48 0.33 3.25e-10 Height; LIHC cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg08888203 chr3:10149979 C3orf24 0.62 6.93 0.35 2.15e-11 Alzheimer's disease; LIHC cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg13395646 chr4:1353034 KIAA1530 -0.52 -8.52 -0.42 5.08e-16 Obesity-related traits; LIHC cis rs921968 0.541 rs634590 chr2:219372768 C/A cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg02951883 chr7:2050386 MAD1L1 -0.76 -13.15 -0.58 3.05e-32 Bipolar disorder and schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00699235 chr12:49962218 MCRS1 0.45 6.92 0.35 2.27e-11 Cognitive function; LIHC cis rs8017423 0.967 rs61989980 chr14:90727635 C/T cg14092571 chr14:90743983 NA -0.38 -6.02 -0.31 4.54e-9 Mortality in heart failure; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg22487209 chr8:27950625 ELP3 -0.57 -6.39 -0.33 5.31e-10 Systolic blood pressure; LIHC cis rs7264396 0.676 rs6058380 chr20:34552900 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg20607798 chr8:58055168 NA 0.64 8.2 0.41 4.94e-15 Developmental language disorder (linguistic errors); LIHC cis rs6831352 0.879 rs29001229 chr4:100046823 A/G cg12011299 chr4:100065546 ADH4 -0.62 -10.53 -0.49 1.17e-22 Alcohol dependence; LIHC cis rs6570726 0.846 rs409553 chr6:145886963 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.62 0.53 1.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs17106184 1.000 rs72902755 chr1:51250908 G/T cg07174182 chr1:51127561 FAF1 -0.61 -6.65 -0.34 1.18e-10 Type 2 diabetes; LIHC cis rs6754311 0.731 rs10207652 chr2:136588478 T/A cg15123519 chr2:136567270 LCT 0.45 9.22 0.45 3.04e-18 Mosquito bite size; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg26338869 chr17:61819248 STRADA 0.6 8.76 0.43 9.47e-17 Prudent dietary pattern; LIHC cis rs9640161 0.789 rs2159234 chr7:150020422 A/T cg17279839 chr7:150038598 RARRES2 0.51 10.68 0.5 3.68e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs1003719 0.751 rs7280371 chr21:38450008 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 6.97e-29 Eye color traits; LIHC cis rs6430585 0.527 rs1446586 chr2:136407445 C/T cg07169764 chr2:136633963 MCM6 -0.64 -8.18 -0.4 5.76e-15 Corneal structure; LIHC cis rs7089973 0.604 rs1359079 chr10:116582502 A/G cg23260525 chr10:116636907 FAM160B1 0.36 7.03 0.36 1.1e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs6060960 0.537 rs6089103 chr20:30464919 G/T cg13852791 chr20:30311386 BCL2L1 0.73 6.88 0.35 2.93e-11 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; LIHC cis rs9388451 0.874 rs9398787 chr6:126090608 A/G cg06289844 chr6:126071538 HEY2 0.38 6.64 0.34 1.24e-10 Brugada syndrome; LIHC cis rs7551222 0.681 rs10900595 chr1:204511602 C/A cg20240347 chr1:204465584 NA -0.37 -7.85 -0.39 5.51e-14 Schizophrenia; LIHC cis rs1348850 0.874 rs4893822 chr2:178285727 G/T cg27490568 chr2:178487706 NA 0.38 5.87 0.3 1.01e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12477438 0.798 rs4622780 chr2:99631760 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.36 -0.64 7.55e-41 Chronic sinus infection; LIHC cis rs4555082 0.834 rs2975217 chr14:105710238 A/C cg13114125 chr14:105738426 BRF1 -0.73 -9.71 -0.46 7.43e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs4713118 0.513 rs149962 chr6:28015918 G/A cg16479474 chr6:28041457 NA 0.38 6.32 0.32 8.32e-10 Parkinson's disease; LIHC cis rs55665837 1.000 rs2305306 chr11:14534999 T/A cg19336497 chr11:14380999 RRAS2 -0.45 -8.01 -0.4 1.79e-14 Vitamin D levels; LIHC cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg13047869 chr3:10149882 C3orf24 0.5 6.07 0.31 3.46e-9 Alzheimer's disease; LIHC cis rs2997447 0.846 rs3008430 chr1:26390328 A/G cg19633962 chr1:26362018 EXTL1 -0.58 -6.53 -0.33 2.43e-10 QRS complex (12-leadsum); LIHC cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs12586317 0.547 rs28577270 chr14:35498443 G/A cg16230307 chr14:35515116 FAM177A1 0.78 13.24 0.58 1.39e-32 Psoriasis; LIHC cis rs258324 0.790 rs2162944 chr16:89717670 G/C cg04240660 chr16:89714849 CHMP1A -0.57 -7.28 -0.37 2.29e-12 Height; LIHC cis rs2115630 0.875 rs8039472 chr15:85361644 A/G cg11189052 chr15:85197271 WDR73 -0.45 -6.58 -0.34 1.8e-10 P wave terminal force; LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg14004847 chr7:1930337 MAD1L1 0.42 5.92 0.31 7.66e-9 Bipolar disorder and schizophrenia; LIHC cis rs1577917 0.958 rs34994386 chr6:86524135 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs2710642 0.611 rs1534418 chr2:62883920 A/G cg17519650 chr2:63277830 OTX1 -0.5 -7.39 -0.37 1.11e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs763121 0.819 rs5757169 chr22:39003495 G/A cg06022373 chr22:39101656 GTPBP1 0.75 15.06 0.63 1.09e-39 Menopause (age at onset); LIHC cis rs1003719 0.788 rs61701101 chr21:38450317 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 6.97e-29 Eye color traits; LIHC cis rs1552244 0.554 rs6443275 chr3:10008819 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.57 8.11 0.4 9.27e-15 Alzheimer's disease; LIHC cis rs1878931 0.501 rs37800 chr16:3423648 T/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.71 -10.63 -0.5 5.34e-23 Body mass index (adult); LIHC cis rs611744 0.967 rs627019 chr8:109222544 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs10489202 1.000 rs7523437 chr1:168029365 A/G cg24449463 chr1:168025552 DCAF6 -0.51 -6.53 -0.33 2.43e-10 Schizophrenia; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.54 0.8 2.06e-77 Prudent dietary pattern; LIHC cis rs34779708 0.931 rs13376801 chr10:35370443 T/C cg03585969 chr10:35415529 CREM 0.85 12.9 0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs918629 0.679 rs3822750 chr5:95276260 C/A cg10483112 chr5:95245456 ELL2 -0.35 -5.91 -0.3 8.46e-9 IgG glycosylation; LIHC cis rs875971 0.862 rs6962717 chr7:65883735 G/A cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs10791097 0.547 rs11222371 chr11:130745719 C/T cg12179176 chr11:130786555 SNX19 0.83 13.82 0.6 8.14e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs858239 0.570 rs10242166 chr7:23162799 A/G cg23682824 chr7:23144976 KLHL7 0.44 6.56 0.33 1.97e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs921968 0.643 rs579610 chr2:219327582 C/A cg18887096 chr2:219472410 PLCD4 0.38 6.88 0.35 2.79e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs6500602 0.627 rs1641866 chr16:4593040 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 7.19 0.36 4.05e-12 Schizophrenia; LIHC cis rs929354 0.772 rs1182364 chr7:157017912 T/C cg16102536 chr7:156981717 UBE3C -0.36 -6.11 -0.31 2.77e-9 Body mass index; LIHC cis rs7100689 0.622 rs2342816 chr10:82086546 G/A cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs763014 0.932 rs35067229 chr16:649638 T/C cg04709771 chr16:646395 RAB40C 0.43 7.97 0.4 2.39e-14 Height; LIHC cis rs3736594 0.513 rs62131882 chr2:27765480 T/C cg27432699 chr2:27873401 GPN1 0.46 6.85 0.35 3.39e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs807029 0.533 rs67692077 chr10:102740271 T/C cg17130504 chr10:102756923 LZTS2 0.56 7.77 0.39 9.27e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs67460515 0.527 rs34221255 chr3:160854123 T/C cg17135325 chr3:160939158 NMD3 0.55 7.62 0.38 2.55e-13 Parkinson's disease; LIHC cis rs929354 0.772 rs1182360 chr7:157020550 C/G cg16102536 chr7:156981717 UBE3C 0.36 6.07 0.31 3.34e-9 Body mass index; LIHC cis rs7552404 0.960 rs12085123 chr1:76149749 G/A cg22875332 chr1:76189707 ACADM 0.48 7.03 0.36 1.16e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6089584 0.854 rs6061985 chr20:60622362 T/C cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs1059312 0.500 rs12303338 chr12:129276641 C/T cg09035930 chr12:129282057 SLC15A4 -0.52 -7.98 -0.4 2.26e-14 Systemic lupus erythematosus; LIHC trans rs208520 0.661 rs851466 chr6:66840476 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.33 -0.41 1.94e-15 Exhaled nitric oxide output; LIHC cis rs7572733 0.555 rs35563720 chr2:198923075 A/G cg03934865 chr2:198174659 NA 0.45 6.32 0.32 8.2e-10 Dermatomyositis; LIHC cis rs9814567 1.000 rs9829092 chr3:134229866 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.06 -0.31 3.65e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12986413 1.000 rs12459350 chr19:2176586 A/G cg09261902 chr19:2140048 AP3D1 0.39 6.67 0.34 1.01e-10 Height; LIHC cis rs10416265 0.527 rs11084699 chr19:33538393 A/T cg27124370 chr19:33622961 WDR88 0.56 8.27 0.41 3.08e-15 Bone properties (heel); LIHC cis rs17102423 0.964 rs11627859 chr14:65602384 G/A cg11161011 chr14:65562177 MAX -0.44 -6.0 -0.31 5.08e-9 Obesity-related traits; LIHC cis rs826838 0.651 rs1843896 chr12:38612913 G/C cg26384229 chr12:38710491 ALG10B 0.45 6.96 0.35 1.73e-11 Heart rate; LIHC cis rs4727027 0.754 rs11764892 chr7:148858916 G/A cg23583168 chr7:148888333 NA -0.7 -8.98 -0.44 1.91e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs4718428 0.705 rs68168107 chr7:66255238 G/A cg10756647 chr7:56101905 PSPH 0.62 8.5 0.42 6.09e-16 Corneal structure; LIHC cis rs11031096 0.655 rs1822289 chr11:4212184 T/C cg18678763 chr11:4115507 RRM1 -0.4 -5.91 -0.3 8.4e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg00684032 chr4:1343700 KIAA1530 0.5 7.28 0.37 2.36e-12 Obesity-related traits; LIHC cis rs9296092 0.560 rs9469505 chr6:33527348 A/G cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs4474465 0.850 rs7938816 chr11:78266227 T/C cg27205649 chr11:78285834 NARS2 0.45 6.72 0.34 7.79e-11 Alzheimer's disease (survival time); LIHC cis rs4920343 0.698 rs591009 chr1:19086869 A/G cg26220594 chr1:19110978 NA 0.28 5.72 0.3 2.38e-8 Knee osteoarthritis; LIHC cis rs3749237 0.615 rs11130202 chr3:49566715 C/T cg06212747 chr3:49208901 KLHDC8B 0.48 6.17 0.32 1.91e-9 Resting heart rate; LIHC cis rs6840360 0.615 rs6836249 chr4:152465829 T/G cg22705602 chr4:152727874 NA -0.32 -6.34 -0.32 7.15e-10 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.643 rs10751671 chr11:944479 T/G ch.11.42038R chr11:967971 AP2A2 0.55 10.04 0.48 5.67e-21 Alzheimer's disease (late onset); LIHC cis rs4908760 0.827 rs10864362 chr1:8732454 A/C cg20416874 chr1:8611966 RERE -0.66 -13.5 -0.59 1.4e-33 Vitiligo; LIHC cis rs1865760 0.892 rs2328903 chr6:25935765 T/C cg12310025 chr6:25882481 NA -0.42 -6.32 -0.32 8.09e-10 Height; LIHC cis rs17685 0.753 rs10952840 chr7:75772878 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg23978390 chr7:1156363 C7orf50 0.48 7.4 0.37 1.05e-12 Longevity;Endometriosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12447188 chr16:4743522 NUDT16L1 -0.5 -6.7 -0.34 8.6e-11 Pancreatic cancer; LIHC cis rs17608059 1.000 rs17608059 chr17:13910549 C/T cg11395062 chr17:14139857 CDRT15 0.51 9.36 0.45 1.07e-18 Temperament; LIHC cis rs7027203 0.828 rs10761288 chr9:96609363 C/T cg13679303 chr9:96623674 NA -0.29 -6.43 -0.33 4.31e-10 DNA methylation (variation); LIHC cis rs9625935 0.518 rs5752972 chr22:30250312 A/T cg01021169 chr22:30184971 ASCC2 0.34 5.92 0.31 7.71e-9 Tonsillectomy; LIHC cis rs2439831 0.850 rs7174208 chr15:44052682 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.43 0.33 4.32e-10 Lung cancer in ever smokers; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg21293397 chr19:35454992 ZNF792 0.49 6.51 0.33 2.6200000000000003e-10 Hepatitis; LIHC cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg12310025 chr6:25882481 NA -1.01 -13.22 -0.58 1.64e-32 Intelligence (multi-trait analysis); LIHC cis rs937213 0.573 rs12592831 chr15:40302441 G/A cg01081584 chr15:40268610 EIF2AK4 -0.36 -6.05 -0.31 3.75e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs4665809 1.000 rs6750681 chr2:26329677 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.75 -0.43 1.02e-16 Gut microbiome composition (summer); LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg07677032 chr17:61819896 STRADA 0.43 6.34 0.32 7.29e-10 Prudent dietary pattern; LIHC cis rs3736485 0.966 rs4775965 chr15:51908251 A/G cg08986416 chr15:51914746 DMXL2 -0.47 -6.97 -0.35 1.64e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9359856 0.564 rs3818133 chr6:90374456 A/G cg13799429 chr6:90582589 CASP8AP2 -0.65 -6.11 -0.31 2.64e-9 Bipolar disorder; LIHC cis rs3859192 0.599 rs2302777 chr17:38179492 A/G cg10374813 chr17:38183790 MED24;SNORD124 -0.32 -5.84 -0.3 1.22e-8 White blood cell count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19552494 chr11:60674271 PRPF19 0.5 7.22 0.36 3.38e-12 Pancreatic cancer; LIHC cis rs4555082 0.718 rs28513571 chr14:105709592 C/A cg10792982 chr14:105748885 BRF1 0.45 6.09 0.31 2.96e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9811920 0.609 rs17174947 chr3:99598884 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs60871478 1.000 rs62432899 chr7:826542 G/C cg27478167 chr7:817139 HEATR2 -0.51 -6.82 -0.35 4.1e-11 Cerebrospinal P-tau181p levels; LIHC trans rs8056893 0.610 rs3803650 chr16:68344696 C/T cg18587063 chr11:122940457 NA 0.37 6.67 0.34 1.02e-10 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs1800469 1.000 rs1549933 chr19:41871142 A/G cg09537434 chr19:41945824 ATP5SL -0.72 -10.09 -0.48 3.9e-21 Colorectal cancer; LIHC cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg05025164 chr4:1340916 KIAA1530 0.43 6.74 0.34 6.8e-11 Obesity-related traits; LIHC cis rs1707322 0.827 rs6683274 chr1:46241638 T/G cg03146154 chr1:46216737 IPP 0.56 9.03 0.44 1.25e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1865760 0.964 rs3799373 chr6:25929173 A/C cg03264133 chr6:25882463 NA -0.38 -5.74 -0.3 2.14e-8 Height; LIHC cis rs611744 0.647 rs631775 chr8:109252746 T/C cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs12915845 0.584 rs7403482 chr15:89062709 A/T cg05013243 chr15:89149849 MIR1179 -0.39 -7.1 -0.36 7.47e-12 Menarche (age at onset); LIHC cis rs904251 0.797 rs1757177 chr6:37486370 C/T cg24148817 chr6:37461033 C6orf129 -0.37 -5.71 -0.3 2.44e-8 Cognitive performance; LIHC cis rs10489202 0.633 rs4657734 chr1:168086743 C/T cg24449463 chr1:168025552 DCAF6 -0.52 -7.74 -0.39 1.15e-13 Schizophrenia; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg24209194 chr3:40518798 ZNF619 0.56 8.12 0.4 8.41e-15 Renal cell carcinoma; LIHC cis rs6461049 0.608 rs3800923 chr7:2184673 A/G cg20295408 chr7:1910781 MAD1L1 -0.4 -6.0 -0.31 4.89e-9 Schizophrenia; LIHC trans rs4843747 0.749 rs72818535 chr16:88074039 G/A cg26811252 chr16:29126840 RRN3P2 0.47 7.32 0.37 1.81e-12 Menopause (age at onset); LIHC cis rs2273669 0.667 rs11153147 chr6:109304058 A/G cg05315195 chr6:109294784 ARMC2 -0.53 -5.83 -0.3 1.29e-8 Prostate cancer; LIHC cis rs9733 0.596 rs17606613 chr1:150683015 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs7777754 0.512 rs7785224 chr7:50562361 T/C cg14593290 chr7:50529359 DDC -0.5 -8.41 -0.41 1.16e-15 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC cis rs4713118 0.662 rs9380045 chr6:28025279 A/G cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC trans rs877282 0.945 rs11253397 chr10:789774 A/G cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg06873352 chr17:61820015 STRADA 0.53 8.6 0.42 2.93e-16 Prudent dietary pattern; LIHC cis rs6570726 0.791 rs379040 chr6:145889035 T/C cg23711669 chr6:146136114 FBXO30 0.65 11.6 0.53 1.83e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC cis rs6450176 0.625 rs35027270 chr5:53289068 T/C ch.5.1024479R chr5:53302184 ARL15 -0.89 -16.49 -0.67 2.23e-45 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs765787 0.530 rs4270107 chr15:45535350 A/G cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs2839186 0.500 rs13052701 chr21:47660045 A/T cg00612595 chr21:47717864 NA -0.42 -6.61 -0.34 1.49e-10 Testicular germ cell tumor; LIHC cis rs7659604 0.521 rs13130789 chr4:122690166 G/A cg19671926 chr4:122722719 EXOSC9 0.55 8.37 0.41 1.5e-15 Type 2 diabetes; LIHC cis rs7116495 0.737 rs634829 chr11:71555128 G/A cg26138937 chr11:71823887 C11orf51 0.64 5.93 0.31 7.44e-9 Severe influenza A (H1N1) infection; LIHC cis rs3812831 0.635 rs6560937 chr13:114945991 C/G cg06611532 chr13:114900021 NA 0.41 7.55 0.38 4.1e-13 Schizophrenia; LIHC cis rs7208859 0.725 rs9897673 chr17:29243366 T/C cg13385521 chr17:29058706 SUZ12P 0.73 7.49 0.38 5.94e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs35306767 0.807 rs61831436 chr10:837882 G/A cg20503657 chr10:835505 NA 1.27 13.03 0.58 8.96e-32 Eosinophil percentage of granulocytes; LIHC cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.33 0.41 1.99e-15 Platelet count; LIHC cis rs7959452 0.535 rs4761228 chr12:69682327 G/A cg14784868 chr12:69753453 YEATS4 0.88 16.66 0.67 4.72e-46 Blood protein levels; LIHC cis rs1691799 0.899 rs1168322 chr12:66743769 C/T cg16791601 chr12:66731901 HELB -0.57 -14.06 -0.61 9.04e-36 White blood cell count (basophil); LIHC cis rs6582630 0.555 rs10748382 chr12:38504529 C/T cg26384229 chr12:38710491 ALG10B 0.68 9.77 0.47 4.85e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs13161895 0.941 rs12519642 chr5:179438626 T/G cg06664874 chr5:179499304 RNF130 -0.58 -7.12 -0.36 6.37e-12 LDL cholesterol; LIHC cis rs1865760 0.786 rs1436308 chr6:25939567 T/G cg15691649 chr6:25882328 NA -0.39 -6.15 -0.32 2.17e-9 Height; LIHC cis rs11229555 0.645 rs12269928 chr11:58184358 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs611744 0.538 rs2298605 chr8:109272006 T/C cg18478394 chr8:109455254 TTC35 0.39 6.64 0.34 1.24e-10 Dupuytren's disease; LIHC cis rs7937682 0.814 rs1784788 chr11:111486136 T/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.71 -0.5 2.78e-23 Primary sclerosing cholangitis; LIHC cis rs140365914 1 rs140365914 chr7:155106570 C/T cg14927855 chr7:155151427 NA 0.35 6.77 0.34 5.68e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg27432699 chr2:27873401 GPN1 -0.5 -7.14 -0.36 5.69e-12 Total body bone mineral density; LIHC cis rs11688816 1.000 rs11688816 chr2:63053048 G/A cg17519650 chr2:63277830 OTX1 -0.5 -7.61 -0.38 2.63e-13 Body mass index; LIHC cis rs17826219 0.636 rs7221463 chr17:29080551 A/C cg14067834 chr17:29058358 SUZ12P 0.69 6.82 0.35 4.05e-11 Body mass index; LIHC cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg11890956 chr21:40555474 PSMG1 1.07 16.08 0.66 1.01e-43 Cognitive function; LIHC cis rs6089829 0.962 rs1060490 chr20:61665871 A/G cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs3859192 0.539 rs2302774 chr17:38183090 G/T cg17467752 chr17:38218738 THRA -0.52 -9.0 -0.44 1.56e-17 White blood cell count; LIHC cis rs826838 0.809 rs11169666 chr12:39211300 T/C cg26384229 chr12:38710491 ALG10B 0.84 10.92 0.51 5.28e-24 Heart rate; LIHC cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg10360323 chr17:41437877 NA 0.4 6.05 0.31 3.83e-9 Menopause (age at onset); LIHC cis rs17376456 0.825 rs10064368 chr5:93266396 C/A cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs9303280 0.628 rs12939565 chr17:38038389 A/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.87 0.3 1.01e-8 Self-reported allergy; LIHC cis rs7474896 0.583 rs1735621 chr10:38167723 G/T cg25427524 chr10:38739819 LOC399744 0.47 5.95 0.31 6.6e-9 Obesity (extreme); LIHC cis rs2991971 0.810 rs781058 chr1:45935056 C/G cg05343316 chr1:45956843 TESK2 0.42 6.16 0.32 2.04e-9 High light scatter reticulocyte count; LIHC cis rs7914558 0.966 rs10748837 chr10:104880236 T/C cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1976403 0.659 rs10799699 chr1:21820961 C/T cg20417195 chr1:21767127 NBPF3 0.38 5.91 0.3 8.49e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs116095464 0.558 rs61689490 chr5:224904 T/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs77637988 0.631 rs7587385 chr2:48600691 T/G cg00032884 chr2:48540671 FOXN2 0.41 6.43 0.33 4.38e-10 Joint mobility (Beighton score); LIHC cis rs600806 0.742 rs12753439 chr1:110015519 G/A cg08911820 chr1:110026001 ATXN7L2 -0.55 -7.04 -0.36 1.04e-11 Intelligence (multi-trait analysis); LIHC cis rs7249142 0.562 rs10417796 chr19:19287072 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.36 -6.06 -0.31 3.56e-9 IgG glycosylation; LIHC cis rs427394 0.664 rs274697 chr5:6731477 A/C cg10857441 chr5:6722123 POLS -0.35 -6.06 -0.31 3.69e-9 Menopause (age at onset); LIHC cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg00149659 chr3:10157352 C3orf10 0.52 5.79 0.3 1.56e-8 Alzheimer's disease; LIHC cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 12.25 0.55 7.7e-29 Colorectal cancer; LIHC cis rs2204008 0.640 rs2320744 chr12:38162389 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs7223966 1.000 rs55674647 chr17:61794195 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 7.31 0.37 1.91e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7264396 0.570 rs1970576 chr20:34336720 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.67 -0.53 1.02e-26 Total cholesterol levels; LIHC cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg17747265 chr1:1875780 NA -0.59 -11.23 -0.52 4.11e-25 Body mass index; LIHC cis rs2115536 1.000 rs11072871 chr15:80197931 T/C cg00225070 chr15:80189496 MTHFS 0.54 8.88 0.43 3.98e-17 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05741837 chr8:27632005 ESCO2 -0.54 -6.25 -0.32 1.22e-9 Systolic blood pressure; LIHC cis rs11758351 1.000 rs16891397 chr6:26200256 C/T cg16070018 chr6:26224392 HIST1H3E 0.55 6.52 0.33 2.6e-10 Gout;Renal underexcretion gout; LIHC cis rs9427116 0.702 rs9427108 chr1:154607914 G/A cg17218026 chr1:154582156 ADAR 0.34 6.51 0.33 2.65e-10 Blood protein levels; LIHC cis rs9303401 0.659 rs35103007 chr17:56900738 G/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.86 0.43 4.46e-17 Cognitive test performance; LIHC cis rs9814567 0.806 rs7648616 chr3:134318074 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs9858542 0.903 rs11917431 chr3:49644012 C/T cg21659725 chr3:3221576 CRBN -0.6 -6.52 -0.33 2.6e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs904251 0.523 rs2776870 chr6:37481364 C/A cg01843034 chr6:37503916 NA -0.48 -8.26 -0.41 3.26e-15 Cognitive performance; LIHC cis rs15676 0.812 rs10819447 chr9:131576416 T/G cg00228799 chr9:131580591 ENDOG 0.47 7.1 0.36 7.14e-12 Blood metabolite levels; LIHC cis rs1005277 0.579 rs1548255 chr10:38417193 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.82e-23 Extrinsic epigenetic age acceleration; LIHC cis rs72781680 0.898 rs72780125 chr2:24000145 T/C cg08917208 chr2:24149416 ATAD2B 0.91 7.89 0.39 4.18e-14 Lymphocyte counts; LIHC cis rs6138458 1.000 rs227624 chr20:24911562 T/C cg26195577 chr20:24973756 C20orf3 1.13 14.83 0.63 9.14e-39 Blood protein levels; LIHC cis rs11958404 0.789 rs72800604 chr5:157502940 C/T cg05962755 chr5:157440814 NA 1.02 11.77 0.54 4.45e-27 IgG glycosylation; LIHC cis rs2742417 1.000 rs1969624 chr3:45734818 C/T cg04837898 chr3:45731254 SACM1L 0.35 5.72 0.3 2.28e-8 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs2439831 0.681 rs7168940 chr15:43633334 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.9 16.72 0.67 2.64e-46 Lung cancer in ever smokers; LIHC cis rs9560113 1.000 rs4773383 chr13:112177764 C/T cg14154082 chr13:112174009 NA 0.29 6.09 0.31 3.03e-9 Menarche (age at onset); LIHC cis rs10078 0.571 rs2241597 chr5:480509 A/G cg24955955 chr5:415729 AHRR 0.58 11.18 0.52 6.04e-25 Fat distribution (HIV); LIHC cis rs7584330 0.554 rs13431733 chr2:238430275 A/G cg08992911 chr2:238395768 MLPH 0.55 6.42 0.33 4.5e-10 Prostate cancer; LIHC cis rs57590327 0.555 rs3772884 chr3:81802720 G/T cg07356753 chr3:81810745 GBE1 -0.54 -8.41 -0.41 1.16e-15 Extraversion; LIHC cis rs9389248 0.690 rs6939543 chr6:135255143 A/G cg24558204 chr6:135376177 HBS1L -0.59 -9.72 -0.47 7.04e-20 High light scatter reticulocyte percentage of red cells; LIHC cis rs9993613 0.935 rs17775434 chr4:73525567 T/C cg15102770 chr4:73434591 ADAMTS3 -0.39 -5.87 -0.3 1.05e-8 Hip circumference adjusted for BMI;Height; LIHC cis rs7223966 1.000 rs11871767 chr17:61698723 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.71 0.34 8.15e-11 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs1814175 0.817 rs10769617 chr11:49810421 G/A cg03929089 chr4:120376271 NA -0.9 -18.4 -0.71 4.84e-53 Height; LIHC cis rs4684776 0.935 rs3816380 chr3:11381973 A/C cg00170343 chr3:11313890 ATG7 -0.49 -6.61 -0.34 1.45e-10 Small vessel stroke; LIHC cis rs9549328 0.800 rs9549326 chr13:113630453 C/T cg08890338 chr13:113700818 MCF2L -0.36 -5.89 -0.3 9.01e-9 Systolic blood pressure; LIHC cis rs950169 0.922 rs67804993 chr15:85104030 T/G cg03959625 chr15:84868606 LOC388152 0.47 6.62 0.34 1.38e-10 Schizophrenia; LIHC cis rs904251 0.737 rs914347 chr6:37484970 A/C cg01843034 chr6:37503916 NA -0.51 -8.23 -0.41 4.1e-15 Cognitive performance; LIHC cis rs74233809 1.000 rs11191582 chr10:104913653 G/A cg03493300 chr10:104813866 CNNM2 0.47 5.88 0.3 9.74e-9 Birth weight; LIHC cis rs1707322 0.685 rs11211177 chr1:46226349 A/G cg03146154 chr1:46216737 IPP 0.55 8.75 0.43 9.62e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 0.572 rs58862481 chr3:10164308 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.89 -9.44 -0.45 6.11e-19 Alzheimer's disease; LIHC cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg06481639 chr22:41940642 POLR3H -0.65 -6.6 -0.34 1.57e-10 Vitiligo; LIHC cis rs1707322 0.752 rs12027622 chr1:46130252 A/C cg03146154 chr1:46216737 IPP 0.57 9.74 0.47 5.94e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10540 1.000 rs61877760 chr11:506596 C/T cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.71e-15 Body mass index; LIHC cis rs1552244 0.882 rs13063929 chr3:10010308 T/C cg08888203 chr3:10149979 C3orf24 0.49 6.13 0.31 2.4e-9 Alzheimer's disease; LIHC cis rs1030877 1.000 rs1030877 chr2:105910513 G/A cg02079111 chr2:105885981 TGFBRAP1 0.68 12.02 0.55 5.23e-28 Obesity-related traits; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg07167872 chr1:205819463 PM20D1 0.63 9.19 0.44 4.03e-18 Menarche (age at onset); LIHC cis rs7216064 1.000 rs2046323 chr17:65849927 T/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7523273 0.565 rs11118451 chr1:207887493 A/G cg22525895 chr1:207977042 MIR29B2 0.53 7.91 0.39 3.54e-14 Schizophrenia; LIHC cis rs10504229 0.679 rs4737454 chr8:58033965 A/T cg20607798 chr8:58055168 NA 0.46 6.71 0.34 7.96e-11 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.06e-11 Alzheimer's disease; LIHC trans rs6693295 0.793 rs2788016 chr1:246244622 A/T cg13514129 chr1:39547527 MACF1 0.4 6.09 0.31 3.02e-9 Migraine - clinic-based;Migraine with aura; LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg04013166 chr16:89971882 TCF25 0.62 8.7 0.43 1.37e-16 Skin colour saturation; LIHC cis rs3096299 0.967 rs16965692 chr16:89471482 C/T cg08822215 chr16:89438651 ANKRD11 -0.41 -6.39 -0.33 5.58e-10 Multiple myeloma (IgH translocation); LIHC cis rs17685 0.753 rs10262501 chr7:75668172 G/A cg16489192 chr7:75678113 MDH2;STYXL1 0.39 6.29 0.32 9.51e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1801251 0.835 rs1446310 chr2:233683245 G/C cg25237894 chr2:233734115 C2orf82 -0.55 -10.17 -0.48 2.04e-21 Coronary artery disease; LIHC cis rs9814567 1.000 rs1880376 chr3:134270347 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11164142 chr4:141565589 TBC1D9 0.51 6.99 0.35 1.45e-11 Pancreatic cancer; LIHC cis rs12701220 0.894 rs8591 chr7:1036799 C/T cg00990874 chr7:1149470 C7orf50 -0.67 -9.33 -0.45 1.34e-18 Bronchopulmonary dysplasia; LIHC cis rs3780378 0.967 rs7023146 chr9:5040163 G/A cg02405213 chr9:5042618 JAK2 -0.56 -9.87 -0.47 2.27e-20 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs11822910 0.911 rs2250887 chr11:57202184 G/A cg00522883 chr11:57194120 SLC43A3 0.68 9.01 0.44 1.48e-17 Platelet distribution width; LIHC cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg17372223 chr3:52568218 NT5DC2 0.37 5.71 0.3 2.41e-8 Bipolar disorder; LIHC cis rs3812831 0.669 rs7327370 chr13:114946858 A/G cg08824895 chr13:115047677 UPF3A 0.51 7.36 0.37 1.38e-12 Schizophrenia; LIHC cis rs8016982 0.962 rs8007841 chr14:81647878 C/T cg01989461 chr14:81687754 GTF2A1 -0.57 -11.2 -0.52 5.17e-25 Schizophrenia; LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.96 -0.31 6.12e-9 Total body bone mineral density; LIHC cis rs1008375 1.000 rs3815413 chr4:17654648 T/C cg16339924 chr4:17578868 LAP3 0.44 6.16 0.32 2.02e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3736485 0.868 rs8034197 chr15:51922506 C/G cg08986416 chr15:51914746 DMXL2 -0.42 -5.9 -0.3 8.86e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9616064 0.557 rs5767318 chr22:47048792 A/G cg05621596 chr22:47072043 GRAMD4 -0.69 -10.7 -0.5 3.08e-23 Urate levels in obese individuals; LIHC cis rs243505 0.660 rs7785022 chr7:148533384 C/T cg09806900 chr7:148480153 CUL1 0.42 6.03 0.31 4.26e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs34172651 0.517 rs1465423 chr16:24772680 C/G cg00339695 chr16:24857497 SLC5A11 -0.72 -10.95 -0.51 3.88e-24 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.577 rs867056 chr6:145784805 A/C cg13319975 chr6:146136371 FBXO30 0.56 8.38 0.41 1.42e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs6430585 0.528 rs7606267 chr2:136668123 T/C cg07169764 chr2:136633963 MCM6 1.28 22.06 0.77 1.09e-67 Corneal structure; LIHC cis rs4474465 0.790 rs10751295 chr11:78266047 T/A cg27205649 chr11:78285834 NARS2 0.39 5.95 0.31 6.6e-9 Alzheimer's disease (survival time); LIHC cis rs4911259 0.552 rs11697394 chr20:31460076 G/A cg13636640 chr20:31349939 DNMT3B -0.61 -10.73 -0.5 2.32e-23 Inflammatory bowel disease; LIHC cis rs7131987 0.617 rs3764953 chr12:29502236 T/C cg14222432 chr12:29376421 FAR2 0.34 6.28 0.32 1.03e-9 QT interval; LIHC cis rs7727544 0.660 rs2631361 chr5:131707380 C/A cg07395648 chr5:131743802 NA 0.31 6.49 0.33 2.97e-10 Blood metabolite levels; LIHC cis rs611744 0.967 rs684904 chr8:109199417 G/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg06558623 chr16:89946397 TCF25 0.95 14.44 0.62 3.05e-37 Skin colour saturation; LIHC cis rs10916814 0.704 rs4655221 chr1:20899265 C/A cg24502330 chr1:20914028 CDA -0.3 -6.7 -0.34 8.63e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs703842 1.000 rs10877015 chr12:58167788 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.86 14.01 0.6 1.51e-35 Multiple sclerosis; LIHC trans rs17685 0.753 rs869804 chr7:75688954 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.32 0.72 9.13e-57 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4555082 0.794 rs2735829 chr14:105708472 C/T cg13114125 chr14:105738426 BRF1 -0.78 -10.12 -0.48 3.16e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs9494142 0.592 rs1547247 chr6:135390836 C/T cg24558204 chr6:135376177 HBS1L 0.54 7.87 0.39 4.87e-14 Lymphocyte counts;Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs870825 0.616 rs1401361 chr4:185643742 G/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs11148252 0.846 rs1056335 chr13:52989863 C/T cg00495681 chr13:53174319 NA 0.38 6.38 0.33 5.86e-10 Lewy body disease; LIHC cis rs3824867 0.920 rs7108143 chr11:47453722 T/G cg20307385 chr11:47447363 PSMC3 -0.57 -7.83 -0.39 6.27e-14 Mean corpuscular hemoglobin; LIHC cis rs9649213 0.613 rs10953256 chr7:97951886 G/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs28735056 0.933 rs72980085 chr18:77631679 A/C cg20368463 chr18:77673604 PQLC1 -0.38 -6.72 -0.34 7.5e-11 Schizophrenia; LIHC cis rs9902453 0.765 rs2447935 chr17:28057524 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -13.61 -0.59 5.27e-34 Coffee consumption (cups per day); LIHC trans rs2727020 0.729 rs2204366 chr11:49349367 A/C cg15704280 chr7:45808275 SEPT13 0.92 16.97 0.68 2.79e-47 Coronary artery disease; LIHC trans rs7677751 0.806 rs67432867 chr4:55104454 A/T cg17183009 chr3:120277827 NA 0.52 6.23 0.32 1.38e-9 Corneal astigmatism; LIHC cis rs589448 0.902 rs528974 chr12:69765918 A/T cg22834771 chr12:69754056 YEATS4 -0.55 -9.98 -0.47 9.62e-21 Cerebrospinal fluid biomarker levels; LIHC cis rs17445774 0.857 rs6435043 chr2:200900974 C/G cg17644776 chr2:200775616 C2orf69 0.52 6.02 0.31 4.41e-9 LDL cholesterol to HDL cholesterol ratio; LIHC cis rs1023500 0.552 rs133368 chr22:42463689 T/C cg04733989 chr22:42467013 NAGA 0.66 9.52 0.46 3.33e-19 Schizophrenia; LIHC cis rs7312774 0.618 rs7979117 chr12:107345883 C/T cg16260113 chr12:107380972 MTERFD3 0.85 11.13 0.52 9.19e-25 Severe influenza A (H1N1) infection; LIHC cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg03452623 chr4:187889614 NA -0.32 -8.21 -0.41 4.56e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs3741404 0.560 rs7938819 chr11:63910116 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.75 -11.8 -0.54 3.38e-27 Platelet count; LIHC cis rs2073499 1.000 rs2071802 chr3:50412945 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.79 8.21 0.41 4.49e-15 Schizophrenia; LIHC cis rs9733 0.596 rs2175615 chr1:150624101 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs7412746 0.611 rs111905669 chr1:150777565 T/C cg17724175 chr1:150552817 MCL1 0.47 9.43 0.45 6.3e-19 Melanoma; LIHC cis rs9303401 1.000 rs1390006 chr17:56890663 C/T cg05425664 chr17:57184151 TRIM37 0.53 7.59 0.38 3.07e-13 Cognitive test performance; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg22528358 chr1:107598549 PRMT6 0.63 10.08 0.48 4.4e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7208859 0.673 rs216410 chr17:28903831 C/G cg13385521 chr17:29058706 SUZ12P -0.6 -5.92 -0.31 7.69e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4555082 0.756 rs76863138 chr14:105736379 C/T cg10792982 chr14:105748885 BRF1 0.45 5.99 0.31 5.18e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg00091569 chr3:40428383 ENTPD3 0.39 6.74 0.34 6.75e-11 Renal cell carcinoma; LIHC cis rs36051895 0.623 rs7870536 chr9:5245493 C/T cg02405213 chr9:5042618 JAK2 -0.63 -10.52 -0.49 1.28e-22 Pediatric autoimmune diseases; LIHC cis rs10792665 0.844 rs7130899 chr11:82644904 G/A cg24227371 chr11:82718527 RAB30 -0.31 -7.42 -0.37 9.15e-13 Obesity-related traits; LIHC cis rs2412488 0.927 rs7691578 chr4:54311275 C/T cg22241045 chr4:54363911 LNX1 -0.42 -6.79 -0.34 4.97e-11 DNA methylation (variation); LIHC cis rs17685 0.712 rs7785025 chr7:75628101 C/T cg16684958 chr7:75615977 POR -0.5 -8.45 -0.42 8.79e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6461049 0.519 rs3778992 chr7:2175313 C/G cg14004847 chr7:1930337 MAD1L1 -0.51 -7.65 -0.38 2e-13 Schizophrenia; LIHC cis rs7617773 0.539 rs13082217 chr3:48383264 T/C cg11946769 chr3:48343235 NME6 0.61 7.52 0.38 4.92e-13 Coronary artery disease; LIHC cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg21016266 chr12:122356598 WDR66 0.51 7.12 0.36 6.23e-12 Mean corpuscular volume; LIHC cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg18357526 chr6:26021779 HIST1H4A 0.45 6.74 0.34 6.82e-11 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15231902 chr12:56618064 OBFC2B -0.46 -6.42 -0.33 4.67e-10 Pancreatic cancer; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg24805985 chr8:25045589 DOCK5 -0.31 -6.2 -0.32 1.6e-9 Monocyte count; LIHC cis rs9911578 0.967 rs686425 chr17:56776730 A/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.61 -0.42 2.72e-16 Intelligence (multi-trait analysis); LIHC cis rs11229555 0.645 rs17474373 chr11:58191243 G/A cg15696309 chr11:58395628 NA -0.65 -7.67 -0.38 1.76e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9368481 0.594 rs7768643 chr6:26891919 C/T cg18867708 chr6:26865862 GUSBL1 0.56 8.5 0.42 5.94e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs910316 1.000 rs13099 chr14:75599155 G/A cg11812906 chr14:75593930 NEK9 -0.76 -15.09 -0.63 8.57e-40 Height; LIHC cis rs2710642 0.611 rs6705835 chr2:62870408 C/T cg17519650 chr2:63277830 OTX1 0.52 7.52 0.38 4.73e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs6831352 0.725 rs2602846 chr4:100025151 T/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Alcohol dependence; LIHC cis rs6430585 0.702 rs3213890 chr2:136552188 G/A cg07169764 chr2:136633963 MCM6 1.17 17.26 0.68 1.82e-48 Corneal structure; LIHC cis rs7551222 0.752 rs4252687 chr1:204497335 G/C cg20240347 chr1:204465584 NA -0.36 -7.68 -0.38 1.64e-13 Schizophrenia; LIHC cis rs12701220 0.894 rs10257744 chr7:1045612 C/T cg00990874 chr7:1149470 C7orf50 -0.68 -9.56 -0.46 2.4e-19 Bronchopulmonary dysplasia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg27056175 chr8:141556352 EIF2C2 -0.43 -6.62 -0.34 1.36e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.85 0.3 1.14e-8 Calcium levels; LIHC cis rs919433 0.647 rs6741205 chr2:198525997 G/C cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1008375 1.000 rs10939743 chr4:17662731 G/A cg16339924 chr4:17578868 LAP3 0.43 6.17 0.32 1.93e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg25072359 chr17:41440525 NA 0.37 5.99 0.31 5.46e-9 Menopause (age at onset); LIHC cis rs4930103 0.935 rs11042167 chr11:2020901 G/A cg06197492 chr11:2016605 H19 0.37 5.93 0.31 7.22e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg02951883 chr7:2050386 MAD1L1 -0.76 -13.15 -0.58 3.05e-32 Bipolar disorder and schizophrenia; LIHC cis rs11644362 1.000 rs976243 chr16:12991679 A/T cg06890432 chr16:12997467 SHISA9 -0.39 -6.63 -0.34 1.34e-10 Positive affect;Subjective well-being; LIHC trans rs4332037 0.950 rs56403963 chr7:1946130 C/G cg11693508 chr17:37793320 STARD3 0.74 7.6 0.38 2.79e-13 Bipolar disorder; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.52 0.56 7.34e-30 Prudent dietary pattern; LIHC cis rs8017423 0.866 rs10184 chr14:90744672 G/A cg04374321 chr14:90722782 PSMC1 -0.78 -14.61 -0.62 6.92e-38 Mortality in heart failure; LIHC cis rs7116495 0.609 rs6592447 chr11:71641093 A/T cg10381502 chr11:71823885 C11orf51 -0.95 -8.2 -0.41 5.03e-15 Severe influenza A (H1N1) infection; LIHC cis rs2235642 0.750 rs1894649 chr16:1657284 C/G cg09025071 chr16:1593152 IFT140;TMEM204 0.3 5.95 0.31 6.54e-9 Coronary artery disease; LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg10755058 chr3:40428713 ENTPD3 0.39 6.62 0.34 1.37e-10 Renal cell carcinoma; LIHC cis rs7208859 0.623 rs11657369 chr17:29136468 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs477692 1.000 rs485576 chr10:131425496 G/C cg05714579 chr10:131428358 MGMT 0.47 7.93 0.39 3.22e-14 Response to temozolomide; LIHC cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg18252515 chr7:66147081 NA -1.24 -15.92 -0.65 4.31e-43 Diabetic kidney disease; LIHC trans rs11088226 0.692 rs8127603 chr21:33886658 T/C cg09050820 chr6:167586206 TCP10L2 0.45 6.76 0.34 5.88e-11 Gastritis; LIHC trans rs3749237 1.000 rs11130216 chr3:49736172 C/A cg21659725 chr3:3221576 CRBN 0.79 12.32 0.55 4.18e-29 Resting heart rate; LIHC cis rs12477438 0.798 rs7570657 chr2:99654281 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.37 -0.41 1.44e-15 Chronic sinus infection; LIHC trans rs9914544 0.564 rs12451220 chr17:18778421 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.59 -0.34 1.68e-10 Educational attainment (years of education); LIHC cis rs904251 0.523 rs2776872 chr6:37482787 C/G cg01843034 chr6:37503916 NA -0.46 -8.06 -0.4 1.3e-14 Cognitive performance; LIHC cis rs10870270 1.000 rs10870232 chr10:133738537 T/G cg08754478 chr10:133766260 PPP2R2D -0.55 -8.16 -0.4 6.45e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs77106637 1.000 rs11602858 chr11:72615069 C/G cg03713592 chr11:72463424 ARAP1 0.77 6.52 0.33 2.49e-10 Type 2 diabetes; LIHC cis rs6121246 0.909 rs6119651 chr20:30259246 G/T cg13852791 chr20:30311386 BCL2L1 0.96 9.51 0.46 3.39e-19 Mean corpuscular hemoglobin; LIHC cis rs10791097 0.739 rs4936120 chr11:130723452 G/A cg09137382 chr11:130731461 NA 0.41 6.26 0.32 1.15e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs16828019 0.789 rs34216154 chr1:41670907 G/A cg03962019 chr1:41807865 NA 0.53 7.64 0.38 2.27e-13 Intelligence (multi-trait analysis); LIHC cis rs13217239 0.646 rs7451149 chr6:27057518 A/G cg12292205 chr6:26970375 C6orf41 -0.43 -7.41 -0.37 1.03e-12 Schizophrenia; LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg14709524 chr16:89940631 TCF25 0.58 7.44 0.37 8.46e-13 Skin colour saturation; LIHC cis rs7044106 1.000 rs7044106 chr9:123494062 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.76 10.95 0.51 3.91e-24 Hip circumference adjusted for BMI; LIHC cis rs1034435 0.547 rs5767174 chr22:48898857 A/G cg05992904 chr22:48892994 FAM19A5 -0.46 -8.33 -0.41 2.04e-15 Late-onset Alzheimer's disease; LIHC cis rs9911578 1.000 rs302840 chr17:56673079 C/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.67 -0.42 1.72e-16 Intelligence (multi-trait analysis); LIHC cis rs76419734 0.510 rs12511885 chr4:106662118 G/A cg24545054 chr4:106630052 GSTCD;INTS12 0.78 9.03 0.44 1.23e-17 Post bronchodilator FEV1; LIHC cis rs7520050 0.933 rs6656022 chr1:46394315 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.37e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2239815 0.515 rs6005917 chr22:29233486 A/G cg15103426 chr22:29168792 CCDC117 0.43 5.74 0.3 2.12e-8 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC cis rs6938 0.618 rs12911254 chr15:75166335 G/A cg14664628 chr15:75095509 CSK -0.49 -6.39 -0.33 5.58e-10 Breast cancer; LIHC cis rs12477438 0.765 rs72957180 chr2:99694452 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.91 -0.54 1.38e-27 Chronic sinus infection; LIHC cis rs17106184 1.000 rs72902785 chr1:51290830 G/A cg07174182 chr1:51127561 FAF1 -0.6 -6.47 -0.33 3.47e-10 Type 2 diabetes; LIHC cis rs9611565 0.592 rs9611613 chr22:41961831 T/C cg03806693 chr22:41940476 POLR3H -0.87 -9.73 -0.47 6.39e-20 Vitiligo; LIHC cis rs9457247 1.000 rs932644 chr6:167404187 A/C cg12798992 chr6:167411361 FGFR1OP 0.6 10.02 0.48 6.67e-21 Crohn's disease; LIHC trans rs3749237 0.964 rs13084243 chr3:49821878 G/C cg21665057 chr3:196295764 WDR53;FBXO45 0.67 10.37 0.49 4.17e-22 Resting heart rate; LIHC cis rs9911578 0.967 rs405684 chr17:56777148 T/C cg05425664 chr17:57184151 TRIM37 -0.58 -8.61 -0.42 2.72e-16 Intelligence (multi-trait analysis); LIHC cis rs317689 0.690 rs317630 chr12:69637847 T/C cg14784868 chr12:69753453 YEATS4 0.51 7.12 0.36 6.25e-12 Response to diuretic therapy; LIHC cis rs4919087 0.926 rs10882884 chr10:99025611 T/A cg25902810 chr10:99078978 FRAT1 0.67 9.82 0.47 3.25e-20 Monocyte count; LIHC cis rs920590 0.679 rs4577973 chr8:19658017 A/G cg03894339 chr8:19674705 INTS10 0.54 8.41 0.41 1.13e-15 Acute lymphoblastic leukemia (childhood); LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg02782426 chr3:40428986 ENTPD3 0.33 6.15 0.32 2.14e-9 Renal cell carcinoma; LIHC cis rs548181 0.736 rs497344 chr11:125470524 T/C cg03464685 chr11:125439445 EI24 0.89 9.79 0.47 4.14e-20 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20999901 chr10:105615046 SH3PXD2A -0.39 -6.24 -0.32 1.28e-9 Calcium levels; LIHC cis rs1568889 0.838 rs7125749 chr11:28154692 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.18 0.61 3.24e-36 Bipolar disorder; LIHC cis rs10751667 0.621 rs7396107 chr11:970029 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs929354 0.742 rs3808317 chr7:156944460 A/G cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6942756 0.956 rs7792317 chr7:128963971 G/A cg02491457 chr7:128862824 NA -0.63 -9.1 -0.44 7.75e-18 White matter hyperintensity burden; LIHC cis rs2075371 0.796 rs12672752 chr7:134007382 C/T cg20476274 chr7:133979776 SLC35B4 0.69 9.38 0.45 9.44e-19 Mean platelet volume; LIHC cis rs4268898 0.717 rs3731626 chr2:24427864 G/A cg06627628 chr2:24431161 ITSN2 -0.64 -8.7 -0.43 1.39e-16 Asthma; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04454426 chr16:70507104 FUK 0.45 6.75 0.34 6.49e-11 Longevity; LIHC cis rs7582180 0.676 rs1437969 chr2:100983482 A/C cg14675211 chr2:100938903 LONRF2 0.52 7.75 0.39 1.08e-13 Intelligence (multi-trait analysis); LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg18918831 chr3:195489782 MUC4 0.69 10.57 0.5 8.65e-23 Lung disease severity in cystic fibrosis; LIHC cis rs921968 0.643 rs3770218 chr2:219525335 C/T cg18887096 chr2:219472410 PLCD4 0.4 6.84 0.35 3.59e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs12699921 0.599 rs6973480 chr7:17978129 C/T cg23563507 chr2:44001149 DYNC2LI1 0.34 6.24 0.32 1.32e-9 Fibrinogen levels; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs713477 0.935 rs7147968 chr14:55909040 G/A cg13175173 chr14:55914753 NA -0.34 -7.99 -0.4 2.14e-14 Pediatric bone mineral content (femoral neck); LIHC trans rs801193 0.660 rs2659897 chr7:66187715 A/G cg10756647 chr7:56101905 PSPH -0.45 -6.8 -0.35 4.81e-11 Aortic root size; LIHC cis rs7940866 0.770 rs10750456 chr11:130819634 A/G cg12179176 chr11:130786555 SNX19 0.64 9.29 0.45 1.8e-18 Schizophrenia; LIHC cis rs6582630 0.519 rs11495699 chr12:38286219 G/T cg26384229 chr12:38710491 ALG10B 0.91 11.48 0.53 5.09e-26 Drug-induced liver injury (flucloxacillin); LIHC cis rs651907 0.535 rs13094911 chr3:101519021 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs6912958 0.684 rs6931069 chr6:88367082 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.43 -7.72 -0.39 1.33e-13 Monocyte percentage of white cells; LIHC cis rs8017423 0.967 rs8022531 chr14:90729931 T/C cg04374321 chr14:90722782 PSMC1 0.78 15.26 0.64 1.75e-40 Mortality in heart failure; LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg06656553 chr16:89960601 TCF25 -0.49 -6.19 -0.32 1.71e-9 Skin colour saturation; LIHC cis rs344364 0.511 rs2917519 chr16:1950479 C/A cg26897989 chr16:1907736 C16orf73 -0.49 -6.14 -0.32 2.25e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs6121246 0.821 rs6058448 chr20:30332396 C/T cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC cis rs9858542 1.000 rs34762726 chr3:49689210 G/A cg03060546 chr3:49711283 APEH -0.63 -8.51 -0.42 5.61e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs16912285 0.748 rs7104550 chr11:24345162 A/G ch.11.24196551F chr11:24239977 NA 0.58 6.13 0.31 2.37e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs798554 0.757 rs2533879 chr7:2859847 G/A cg19717773 chr7:2847554 GNA12 -0.44 -6.95 -0.35 1.81e-11 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07761912 chr1:179846929 TOR1AIP2 0.48 6.46 0.33 3.52e-10 Lung function (FEV1/FVC); LIHC cis rs1005277 0.579 rs2749616 chr10:38510993 A/T cg25427524 chr10:38739819 LOC399744 -0.72 -13.99 -0.6 1.75e-35 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs11644362 1.000 rs4505301 chr16:12989467 A/G cg06890432 chr16:12997467 SHISA9 -0.4 -6.86 -0.35 3.34e-11 Positive affect;Subjective well-being; LIHC cis rs7412746 0.658 rs6669855 chr1:150861229 C/T cg17724175 chr1:150552817 MCL1 0.43 8.61 0.42 2.71e-16 Melanoma; LIHC cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg02503808 chr4:7069936 GRPEL1 0.79 11.74 0.54 5.51e-27 Monocyte percentage of white cells; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg11015505 chr11:64645556 EHD1 0.43 6.11 0.31 2.68e-9 Hepatitis; LIHC cis rs7098414 0.511 rs10887828 chr10:82151470 T/C cg00277334 chr10:82204260 NA -0.61 -10.14 -0.48 2.58e-21 Post bronchodilator FEV1; LIHC cis rs651907 0.535 rs13065944 chr3:101473088 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.4 0.49 3.31e-22 Colorectal cancer; LIHC cis rs6963495 0.585 rs1728653 chr7:105191335 A/G cg19920283 chr7:105172520 RINT1 0.62 7.45 0.37 7.92e-13 Bipolar disorder (body mass index interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12580275 chr1:205744413 RAB7L1 0.41 6.15 0.32 2.13e-9 Cognitive function; LIHC cis rs1348850 0.567 rs880897 chr2:178532503 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.67 0.38 1.84e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs17401966 0.867 rs12403443 chr1:10423988 A/G cg19773385 chr1:10388646 KIF1B -0.46 -7.57 -0.38 3.55e-13 Hepatocellular carcinoma; LIHC cis rs6582630 0.599 rs1589392 chr12:38418535 G/C cg26384229 chr12:38710491 ALG10B -0.46 -5.97 -0.31 5.87e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs2439831 0.850 rs524417 chr15:43772374 C/T cg15269541 chr15:43626905 ADAL -0.3 -5.91 -0.3 8.21e-9 Lung cancer in ever smokers; LIHC cis rs208520 0.526 rs6455072 chr6:66797215 A/G cg07460842 chr6:66804631 NA -1.01 -19.45 -0.72 2.87e-57 Exhaled nitric oxide output; LIHC cis rs11971779 0.616 rs6944244 chr7:139051186 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC trans rs916888 0.821 rs199513 chr17:44856932 A/G cg07870213 chr5:140052090 DND1 -0.85 -8.87 -0.43 4.05e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs965469 1.000 rs2236092 chr20:3258188 G/C cg25506879 chr20:3388711 C20orf194 -0.6 -7.17 -0.36 4.77e-12 IFN-related cytopenia; LIHC cis rs4699052 0.963 rs4698890 chr4:104181878 T/C cg16532752 chr4:104119610 CENPE -0.4 -6.33 -0.32 7.56e-10 Testicular germ cell tumor; LIHC cis rs875971 0.545 rs7810213 chr7:65946579 G/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.34 6.78 0.34 5.43e-11 Aortic root size; LIHC cis rs12594515 1.000 rs8039622 chr15:45986431 A/G cg19682013 chr15:45996608 NA 0.41 7.25 0.37 2.78e-12 Waist circumference;Weight; LIHC cis rs11122272 0.766 rs2808608 chr1:231543175 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.26 0.45 2.39e-18 Hemoglobin concentration; LIHC cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.57 8.61 0.42 2.64e-16 Schizophrenia; LIHC cis rs1577917 0.958 rs12209259 chr6:86502348 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.32 -5.72 -0.3 2.34e-8 Response to antipsychotic treatment; LIHC cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.850 rs11076623 chr16:89844120 G/T cg19635926 chr16:89946313 TCF25 0.52 6.54 0.33 2.24e-10 Skin colour saturation; LIHC cis rs1799949 0.965 rs8067269 chr17:41235799 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.16e-8 Menopause (age at onset); LIHC cis rs6964587 0.692 rs7807490 chr7:91773359 A/G cg17063962 chr7:91808500 NA 0.68 12.24 0.55 8.15e-29 Breast cancer; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg11494091 chr17:61959527 GH2 0.46 8.31 0.41 2.24e-15 Prudent dietary pattern; LIHC cis rs3018712 0.508 rs4930581 chr11:68411093 A/G cg16797656 chr11:68205561 LRP5 -0.44 -5.83 -0.3 1.28e-8 Total body bone mineral density; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg02853322 chr7:39989723 CDK13 -0.48 -6.19 -0.32 1.74e-9 Lung function (FEV1); LIHC cis rs477692 0.685 rs551491 chr10:131397821 G/A cg19680672 chr10:131412579 MGMT -0.41 -6.44 -0.33 3.98e-10 Response to temozolomide; LIHC cis rs9818758 0.607 rs12715434 chr3:49295025 G/C cg00383909 chr3:49044727 WDR6 0.79 6.68 0.34 9.53e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2730245 1.000 rs2527199 chr7:158737113 G/A cg24397884 chr7:158709396 WDR60 -0.41 -6.42 -0.33 4.48e-10 Height; LIHC cis rs74417235 0.517 rs13179034 chr5:154059487 C/A cg08754654 chr5:154026448 NA 0.32 7.17 0.36 4.54e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs1003719 0.725 rs2187101 chr21:38452379 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.79 12.29 0.55 5.25e-29 Eye color traits; LIHC cis rs7520050 0.966 rs4073846 chr1:46462881 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 -0.39 -5.78 -0.3 1.68e-8 Red blood cell count;Reticulocyte count; LIHC trans rs2727020 0.930 rs1164688 chr11:49290604 C/G cg15704280 chr7:45808275 SEPT13 0.77 11.7 0.53 8.12e-27 Coronary artery disease; LIHC cis rs3020736 0.500 rs6002597 chr22:42488160 C/A cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.23 -0.32 1.39e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg20607798 chr8:58055168 NA 0.49 6.07 0.31 3.33e-9 Developmental language disorder (linguistic errors); LIHC cis rs992157 0.560 rs7605980 chr2:219100869 C/G cg20019365 chr2:219134978 PNKD;AAMP 0.74 11.98 0.54 7.37e-28 Colorectal cancer; LIHC cis rs11951515 0.508 rs7706431 chr5:43582423 C/T cg01983248 chr5:43482804 C5orf28 -0.37 -6.06 -0.31 3.64e-9 Metabolite levels (X-11787); LIHC cis rs8103278 0.507 rs16939 chr19:46276056 C/A cg12641515 chr19:46296257 DMWD 0.46 7.03 0.36 1.16e-11 Coronary artery disease; LIHC cis rs17401966 0.898 rs11587495 chr1:10448999 T/C cg19773385 chr1:10388646 KIF1B -0.38 -6.39 -0.33 5.34e-10 Hepatocellular carcinoma; LIHC cis rs7772486 0.754 rs4360151 chr6:146255079 A/C cg05347473 chr6:146136440 FBXO30 -0.35 -5.79 -0.3 1.63e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7528419 0.895 rs583104 chr1:109821307 G/T cg00908766 chr1:109817496 CELSR2 0.42 7.85 0.39 5.34e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs6426558 0.502 rs1929858 chr1:227220175 C/A cg10327440 chr1:227177885 CDC42BPA 0.43 6.29 0.32 9.83e-10 Neutrophil percentage of white cells; LIHC cis rs6912958 0.631 rs9450704 chr6:88182704 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.04 -0.36 1.07e-11 Monocyte percentage of white cells; LIHC cis rs8180040 0.620 rs11715121 chr3:47072621 T/A cg27129171 chr3:47204927 SETD2 -0.54 -9.08 -0.44 8.92e-18 Colorectal cancer; LIHC cis rs7572733 0.534 rs1518361 chr2:198812874 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.91 0.35 2.32e-11 Dermatomyositis; LIHC cis rs1023500 0.573 rs133370 chr22:42465260 T/C cg15557168 chr22:42548783 NA -0.42 -6.7 -0.34 8.59e-11 Schizophrenia; LIHC cis rs11252926 0.574 rs4881313 chr10:487973 C/T cg16386425 chr10:429943 DIP2C 0.35 5.93 0.31 7.61e-9 Psychosis in Alzheimer's disease; LIHC cis rs4906332 1.000 rs7155822 chr14:103922390 A/G cg19000871 chr14:103996768 TRMT61A -0.45 -7.61 -0.38 2.63e-13 Coronary artery disease; LIHC cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.44 6.2 0.32 1.65e-9 Schizophrenia; LIHC cis rs7592578 0.766 rs35818159 chr2:191409616 C/G cg27211696 chr2:191398769 TMEM194B -0.65 -8.46 -0.42 7.96e-16 Diastolic blood pressure; LIHC cis rs10489202 1.000 rs11587594 chr1:167989180 A/T cg24449463 chr1:168025552 DCAF6 -0.52 -6.38 -0.33 5.84e-10 Schizophrenia; LIHC cis rs4237845 0.742 rs6650219 chr12:58289100 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.43 5.95 0.31 6.68e-9 Intelligence (multi-trait analysis); LIHC cis rs9486719 1.000 rs2472887 chr6:96865437 A/G cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC trans rs7618501 1.000 rs1049256 chr3:49763338 T/C cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.505 rs13503 chr10:38239843 C/A cg00409905 chr10:38381863 ZNF37A 0.56 9.74 0.47 6.01e-20 Extrinsic epigenetic age acceleration; LIHC cis rs7520050 0.966 rs6661910 chr1:46290632 A/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.12 0.31 2.54e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1395 0.744 rs11126935 chr2:27476740 G/T cg22903471 chr2:27725779 GCKR -0.4 -6.0 -0.31 4.98e-9 Blood metabolite levels; LIHC trans rs1814175 0.645 rs1721996 chr11:49915527 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs5769765 0.773 rs9616378 chr22:50311973 A/G cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs7582180 0.606 rs12618908 chr2:100947026 A/T cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.97e-16 Intelligence (multi-trait analysis); LIHC cis rs2439831 1.000 rs2254321 chr15:43707542 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.64 8.93 0.43 2.72e-17 Lung cancer in ever smokers; LIHC cis rs7572733 0.534 rs6434943 chr2:198762192 T/G cg03934865 chr2:198174659 NA 0.47 6.74 0.34 6.87e-11 Dermatomyositis; LIHC cis rs4555082 0.645 rs2816605 chr14:105715515 C/T cg13114125 chr14:105738426 BRF1 -0.81 -10.37 -0.49 4.36e-22 Mean platelet volume;Platelet distribution width; LIHC cis rs2839186 0.585 rs2839154 chr21:47637760 C/T cg00612595 chr21:47717864 NA 0.34 5.85 0.3 1.17e-8 Testicular germ cell tumor; LIHC cis rs2067615 0.542 rs11113120 chr12:107203460 T/C cg15890332 chr12:107067104 RFX4 0.26 6.11 0.31 2.79e-9 Heart rate; LIHC cis rs875971 0.862 rs6958294 chr7:65794796 C/A cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs9733 0.565 rs11804276 chr1:150685761 T/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs6582630 0.519 rs1607882 chr12:38361657 G/A cg26384229 chr12:38710491 ALG10B 0.56 7.78 0.39 8.61e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.49 0.56 9.6e-30 Prudent dietary pattern; LIHC cis rs1003719 0.737 rs9974374 chr21:38479885 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.76 11.71 0.54 7.21e-27 Eye color traits; LIHC cis rs7666738 0.830 rs28619044 chr4:98789814 G/C cg05340658 chr4:99064831 C4orf37 0.63 11.49 0.53 4.5e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs7927771 0.542 rs6485775 chr11:47773518 A/G cg20307385 chr11:47447363 PSMC3 -0.65 -9.63 -0.46 1.42e-19 Subjective well-being; LIHC cis rs798554 0.757 rs1182187 chr7:2870454 T/G cg19346786 chr7:2764209 NA -0.41 -5.84 -0.3 1.21e-8 Height; LIHC cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs11671005 0.735 rs12977592 chr19:58961056 C/G cg13877915 chr19:58951672 ZNF132 0.54 6.18 0.32 1.87e-9 Mean platelet volume; LIHC cis rs227584 0.501 rs62078931 chr17:42198059 A/C cg10896456 chr17:42255109 ASB16;C17orf65 -0.41 -7.42 -0.37 9.58e-13 Bone mineral density (hip);Bone mineral density; LIHC cis rs1552244 0.882 rs28366039 chr3:10028988 C/A cg08888203 chr3:10149979 C3orf24 0.48 6.1 0.31 2.81e-9 Alzheimer's disease; LIHC cis rs9916302 0.706 rs6503500 chr17:37485925 C/T cg07936489 chr17:37558343 FBXL20 -0.86 -12.33 -0.55 3.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs8058578 1.000 rs67128646 chr16:30672097 A/C cg02466173 chr16:30829666 NA -0.46 -7.03 -0.36 1.14e-11 Multiple myeloma; LIHC cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg27572855 chr1:25598939 RHD 0.41 8.82 0.43 5.95e-17 Plateletcrit;Mean corpuscular volume; LIHC cis rs1577917 0.816 rs9353349 chr6:86707725 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.33 5.75 0.3 2e-8 Response to antipsychotic treatment; LIHC cis rs6690583 0.623 rs12042160 chr1:85504516 A/G cg22153463 chr1:85462885 MCOLN2 0.49 5.87 0.3 1.03e-8 Serum sulfate level; LIHC cis rs1789 0.872 rs4333182 chr4:15684712 G/A cg24225360 chr4:15471699 CC2D2A -0.38 -5.82 -0.3 1.37e-8 Blood protein levels; LIHC cis rs10504229 1.000 rs72652905 chr8:58188355 A/G cg02290350 chr8:58132656 NA 0.38 7.9 0.39 3.9e-14 Developmental language disorder (linguistic errors); LIHC cis rs2257205 0.588 rs77430462 chr17:56804085 C/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.56 -0.33 2e-10 Pancreatic cancer; LIHC trans rs8073060 0.544 rs1080352 chr17:34002362 A/G cg19694781 chr19:47549865 TMEM160 -1.25 -13.18 -0.58 2.36e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg20887711 chr4:1340912 KIAA1530 0.81 12.35 0.56 3.16e-29 Longevity; LIHC cis rs2574704 0.851 rs2251175 chr3:11661600 G/A cg15876825 chr3:11651881 VGLL4 -0.49 -7.93 -0.39 3.12e-14 Body mass index; LIHC cis rs1008375 1.000 rs3846357 chr4:17635887 A/T cg15017067 chr4:17643749 FAM184B 0.34 5.84 0.3 1.23e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs483180 0.512 rs606312 chr1:120222582 G/A cg19096424 chr1:120255104 PHGDH 0.62 7.79 0.39 8.1e-14 Macular telangiectasia type 2; LIHC cis rs10089 0.953 rs4836359 chr5:127385518 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.16e-11 Ileal carcinoids; LIHC cis rs9918079 0.560 rs10008376 chr4:15623955 A/G cg24225360 chr4:15471699 CC2D2A 0.38 6.0 0.31 4.97e-9 Obesity-related traits; LIHC cis rs7520050 1.000 rs785511 chr1:46534498 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.73 0.3 2.18e-8 Red blood cell count;Reticulocyte count; LIHC cis rs17286411 0.750 rs11075910 chr16:71936733 A/G cg03805757 chr16:71968109 PKD1L3 0.43 6.06 0.31 3.53e-9 Blood protein levels; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs74181299 1.000 rs74181299 chr2:65283972 T/C cg05010058 chr2:65284262 CEP68 0.41 7.03 0.36 1.13e-11 Pulse pressure; LIHC cis rs344364 0.511 rs1742469 chr16:1950244 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.27 -0.37 2.54e-12 Glomerular filtration rate in chronic kidney disease; LIHC trans rs1814175 0.645 rs11040702 chr11:50024827 C/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC trans rs875971 1.000 rs6460295 chr7:65882728 T/C cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs4555082 0.874 rs4677 chr14:105717279 T/C cg13114125 chr14:105738426 BRF1 -0.71 -9.46 -0.46 5.2e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs3849570 1.000 rs78242412 chr3:81747219 A/G cg07356753 chr3:81810745 GBE1 -0.6 -9.65 -0.46 1.21e-19 Waist circumference;Body mass index; LIHC cis rs7572733 0.534 rs6760891 chr2:198768166 T/G cg10820045 chr2:198174542 NA 0.49 7.4 0.37 1.05e-12 Dermatomyositis; LIHC cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg17554472 chr22:41940697 POLR3H 0.57 6.4 0.33 5.03e-10 Vitiligo; LIHC cis rs11864453 0.826 rs12325142 chr16:72138112 G/T cg16558253 chr16:72132732 DHX38 -0.51 -8.15 -0.4 6.91e-15 Fibrinogen levels; LIHC cis rs10416265 0.528 rs3786932 chr19:33620488 T/A cg27124370 chr19:33622961 WDR88 0.52 7.32 0.37 1.75e-12 Bone properties (heel); LIHC cis rs13392177 0.684 rs6720105 chr2:219080718 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.56 -7.9 -0.39 3.86e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs12477438 1.000 rs6732980 chr2:99921613 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -7.65 -0.38 2.05e-13 Chronic sinus infection; LIHC cis rs11626933 1.000 rs3825661 chr14:90767607 C/T cg14092571 chr14:90743983 NA 0.9 14.89 0.63 5.5e-39 Gut microbiota (bacterial taxa); LIHC cis rs1046896 0.503 rs12947062 chr17:80686370 A/G cg02398342 chr17:80708632 TBCD;FN3K -0.45 -6.9 -0.35 2.54e-11 Glycated hemoglobin levels; LIHC trans rs637571 0.726 rs689274 chr11:65665988 A/G cg17712092 chr4:129076599 LARP1B -0.76 -11.83 -0.54 2.63e-27 Eosinophil percentage of white cells; LIHC trans rs11098499 0.955 rs7685268 chr4:120162188 G/A cg25214090 chr10:38739885 LOC399744 0.52 7.89 0.39 4.08e-14 Corneal astigmatism; LIHC cis rs10493773 0.894 rs12067749 chr1:86197922 T/C cg17807903 chr1:86174739 ZNHIT6 -0.51 -8.5 -0.42 6.12e-16 Urate levels in overweight individuals; LIHC trans rs10028773 0.546 rs13117947 chr4:120257060 A/G cg25214090 chr10:38739885 LOC399744 0.4 6.58 0.34 1.72e-10 Educational attainment; LIHC cis rs35110281 0.506 rs13051661 chr21:45111518 A/T cg04455712 chr21:45112962 RRP1B 0.55 9.32 0.45 1.53e-18 Mean corpuscular volume; LIHC cis rs9916302 0.861 rs11658219 chr17:37709782 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.12 -0.58 4.01e-32 Glomerular filtration rate (creatinine); LIHC cis rs6952808 0.756 rs12537348 chr7:1948172 C/G cg20295408 chr7:1910781 MAD1L1 -0.52 -7.47 -0.37 6.61e-13 Bipolar disorder and schizophrenia; LIHC cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg09904177 chr6:26538194 HMGN4 0.56 10.96 0.51 3.78e-24 Intelligence (multi-trait analysis); LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg21843114 chr4:26334859 RBPJ 0.47 6.81 0.35 4.33e-11 Thyroid stimulating hormone; LIHC trans rs11098499 0.738 rs28687057 chr4:120280812 A/G cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs11148252 0.553 rs2147692 chr13:53287023 C/G cg12458913 chr13:53173898 NA 0.51 8.39 0.41 1.3e-15 Lewy body disease; LIHC cis rs7552404 0.924 rs7546641 chr1:76158035 T/C cg03433033 chr1:76189801 ACADM 0.69 10.58 0.5 8e-23 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2997447 0.846 rs3008230 chr1:26401331 A/G cg19633962 chr1:26362018 EXTL1 -0.52 -5.94 -0.31 6.97e-9 QRS complex (12-leadsum); LIHC trans rs7120489 0.643 rs6485725 chr11:12446262 A/G cg08537300 chr5:179058959 NA 0.57 6.18 0.32 1.84e-9 Mortality in heart failure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02926110 chr15:72411069 MYO9A;SENP8 0.44 6.35 0.32 6.96e-10 Cognitive function; LIHC cis rs2439831 0.717 rs7165471 chr15:43644788 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs801193 1.000 rs2659889 chr7:66217112 A/G cg11764359 chr7:65958608 NA 0.71 10.63 0.5 5.35e-23 Aortic root size; LIHC cis rs8053891 0.756 rs12708921 chr16:71999589 G/A cg01557791 chr16:72042693 DHODH -0.46 -6.75 -0.34 6.37e-11 Coronary artery disease; LIHC cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg14004847 chr7:1930337 MAD1L1 -0.42 -6.15 -0.32 2.14e-9 Bipolar disorder and schizophrenia; LIHC cis rs763121 0.853 rs1062687 chr22:39134715 T/C cg06022373 chr22:39101656 GTPBP1 0.72 13.96 0.6 2.39e-35 Menopause (age at onset); LIHC cis rs2439831 1.000 rs2245908 chr15:43731454 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.94 0.44 2.42e-17 Lung cancer in ever smokers; LIHC cis rs11190604 1.000 rs10883508 chr10:102294413 G/A cg07080220 chr10:102295463 HIF1AN 0.55 8.03 0.4 1.58e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9916302 0.904 rs8081338 chr17:37406139 C/T cg03013999 chr17:37608204 MED1 0.34 5.75 0.3 2.03e-8 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg18252515 chr7:66147081 NA 1.28 17.42 0.69 4.2e-49 Diabetic kidney disease; LIHC cis rs2991971 0.810 rs12119202 chr1:45925931 A/T cg05343316 chr1:45956843 TESK2 0.44 6.51 0.33 2.63e-10 High light scatter reticulocyte count; LIHC cis rs66569888 0.633 rs11680226 chr2:106745044 A/G cg16099169 chr2:106886729 NA 0.63 6.75 0.34 6.44e-11 Facial morphology (factor 23); LIHC cis rs17401966 0.838 rs12120042 chr1:10345325 A/T cg19773385 chr1:10388646 KIF1B -0.4 -7.3 -0.37 2.02e-12 Hepatocellular carcinoma; LIHC cis rs711245 0.699 rs3770818 chr2:36769497 T/G cg09467607 chr2:36825704 FEZ2 0.51 7.48 0.37 6.36e-13 Height; LIHC cis rs10791097 0.694 rs1050071 chr11:130747231 C/G cg12179176 chr11:130786555 SNX19 0.8 12.1 0.55 2.62e-28 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs8017423 0.935 rs59444150 chr14:90767175 T/C cg14092571 chr14:90743983 NA -0.4 -6.3 -0.32 8.9e-10 Mortality in heart failure; LIHC cis rs59698941 0.943 rs67462411 chr5:132220031 C/T cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -12.86 -0.57 3.77e-31 Alzheimer's disease; LIHC cis rs28830936 0.966 rs4924576 chr15:42119593 C/A cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.07 -0.31 3.48e-9 Diastolic blood pressure; LIHC trans rs66887589 0.807 rs13134517 chr4:120405262 G/A cg25214090 chr10:38739885 LOC399744 0.39 6.51 0.33 2.75e-10 Diastolic blood pressure; LIHC cis rs2997447 0.655 rs2275947 chr1:26383875 A/G cg19633962 chr1:26362018 EXTL1 -0.6 -7.36 -0.37 1.38e-12 QRS complex (12-leadsum); LIHC cis rs72781680 0.821 rs12623521 chr2:24181670 C/T cg08917208 chr2:24149416 ATAD2B 0.62 6.25 0.32 1.25e-9 Lymphocyte counts; LIHC cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg03806693 chr22:41940476 POLR3H -0.96 -11.2 -0.52 5.16e-25 Vitiligo; LIHC cis rs826838 1.000 rs1393537 chr12:38920961 C/T cg26384229 chr12:38710491 ALG10B 0.97 13.1 0.58 4.65e-32 Heart rate; LIHC trans rs61931739 0.500 rs11053140 chr12:34316122 T/C cg26384229 chr12:38710491 ALG10B 0.57 7.41 0.37 9.8e-13 Morning vs. evening chronotype; LIHC cis rs894734 0.535 rs7301643 chr12:54325796 G/T cg17410650 chr12:54324560 NA -0.41 -7.93 -0.39 3.16e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs2153535 0.580 rs9406159 chr6:8464859 C/G cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs17685 0.712 rs10271413 chr7:75754858 G/A cg01364799 chr7:75623366 TMEM120A -0.5 -7.52 -0.38 4.97e-13 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10620530 chr9:139922595 C9orf139;ABCA2 0.4 6.43 0.33 4.38e-10 Pancreatic cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08128889 chr17:80828176 TBCD -0.37 -6.27 -0.32 1.11e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs798554 1.000 rs798548 chr7:2760935 A/G cg04166393 chr7:2884313 GNA12 0.43 6.07 0.31 3.49e-9 Height; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg09951433 chr7:101843287 CUX1 0.37 6.27 0.32 1.06e-9 Calcium levels; LIHC cis rs921968 0.643 rs832806 chr2:219473914 A/T cg18887096 chr2:219472410 PLCD4 0.34 5.8 0.3 1.54e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs67478160 0.643 rs12880821 chr14:104276049 C/T cg24130564 chr14:104152367 KLC1 -0.35 -5.74 -0.3 2.07e-8 Schizophrenia; LIHC cis rs801193 1.000 rs2707850 chr7:66203870 G/T cg18876405 chr7:65276391 NA 0.42 7.32 0.37 1.79e-12 Aortic root size; LIHC cis rs35306767 0.903 rs12244355 chr10:944465 T/C cg20503657 chr10:835505 NA 1.03 12.24 0.55 8.27e-29 Eosinophil percentage of granulocytes; LIHC cis rs919433 0.929 rs7592511 chr2:198177974 A/G cg10820045 chr2:198174542 NA -0.61 -10.35 -0.49 5.05e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs916888 0.821 rs199512 chr17:44857352 T/C cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs722599 1.000 rs722599 chr14:75327443 T/C cg08847533 chr14:75593920 NEK9 -0.47 -7.46 -0.37 7.3e-13 IgG glycosylation; LIHC cis rs2952156 0.684 rs931992 chr17:37821435 G/T cg00129232 chr17:37814104 STARD3 -0.59 -11.55 -0.53 2.8e-26 Asthma; LIHC cis rs7904368 0.806 rs3858182 chr10:16855094 C/T cg14835575 chr10:16859367 RSU1 0.65 8.95 0.44 2.24e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs4908760 0.792 rs11121215 chr1:8733128 T/C cg20416874 chr1:8611966 RERE -0.63 -12.27 -0.55 6.37e-29 Vitiligo; LIHC cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg12311346 chr5:56204834 C5orf35 0.67 8.61 0.42 2.62e-16 Initial pursuit acceleration; LIHC cis rs5769707 0.967 rs763127 chr22:50006078 C/T cg07959070 chr22:50026188 C22orf34 -0.33 -8.7 -0.43 1.47e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg06634786 chr22:41940651 POLR3H -0.69 -7.65 -0.38 2.01e-13 Vitiligo; LIHC cis rs13191362 1.000 rs13199223 chr6:163001083 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs868943 0.582 rs12196141 chr6:116489550 C/T cg08036074 chr6:116424633 NT5DC1 0.58 6.15 0.32 2.18e-9 Total cholesterol levels; LIHC cis rs4665809 0.590 rs7606351 chr2:26292545 A/C cg04944784 chr2:26401820 FAM59B -0.71 -8.97 -0.44 1.97e-17 Gut microbiome composition (summer); LIHC cis rs7264396 0.790 rs6121026 chr20:34266883 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.61 -0.53 1.76e-26 Total cholesterol levels; LIHC cis rs4788570 0.584 rs8051968 chr16:71761978 C/A cg06353428 chr16:71660113 MARVELD3 1.42 15.9 0.65 5.23e-43 Intelligence (multi-trait analysis); LIHC cis rs4808199 0.947 rs4808960 chr19:19574277 G/C cg21559469 chr19:19431446 KIAA0892;SF4 0.42 5.73 0.3 2.21e-8 Nonalcoholic fatty liver disease; LIHC cis rs700651 0.752 rs7592556 chr2:198891021 G/A cg03934865 chr2:198174659 NA 0.45 6.54 0.33 2.22e-10 Intracranial aneurysm; LIHC cis rs1055129 0.560 rs56248937 chr17:73915153 T/A cg08125733 chr17:73851984 WBP2 0.55 8.59 0.42 3.08e-16 White matter hyperintensity burden; LIHC cis rs875971 0.545 rs316324 chr7:65610614 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.37 -7.5 -0.38 5.7e-13 Aortic root size; LIHC cis rs9473924 0.542 rs2744504 chr6:50798668 G/C cg14470998 chr6:50812995 TFAP2B 0.98 11.01 0.51 2.45e-24 Body mass index; LIHC cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg03517284 chr6:25882590 NA -1.01 -12.33 -0.55 3.63e-29 Intelligence (multi-trait analysis); LIHC cis rs7512552 0.839 rs1694385 chr1:150377960 G/A cg15654264 chr1:150340011 RPRD2 0.69 11.25 0.52 3.29e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs4689592 0.503 rs59640165 chr4:7051661 G/A cg26116260 chr4:7069785 GRPEL1 -1.0 -16.82 -0.67 1.07e-46 Monocyte percentage of white cells; LIHC cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg11644478 chr21:40555479 PSMG1 0.83 10.86 0.51 8.58e-24 Cognitive function; LIHC cis rs10744422 0.800 rs6489240 chr12:123275030 T/C cg22842854 chr12:123319900 HIP1R -0.64 -8.02 -0.4 1.68e-14 Schizophrenia; LIHC trans rs9929218 0.954 rs17715762 chr16:68828250 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -8.01 -0.4 1.83e-14 Colorectal cancer; LIHC cis rs11123170 0.650 rs2289897 chr2:113977454 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.55 6.74 0.34 6.86e-11 Renal function-related traits (BUN); LIHC cis rs7236492 0.532 rs8090536 chr18:77195553 C/T cg15644404 chr18:77186268 NFATC1 -0.37 -5.75 -0.3 2e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7296418 0.699 rs11057254 chr12:123794581 A/C cg05973401 chr12:123451056 ABCB9 0.41 6.29 0.32 9.5e-10 Platelet count; LIHC trans rs4650994 0.525 rs2493865 chr1:178545016 G/A cg05059571 chr16:84539110 KIAA1609 0.45 7.51 0.38 5.3e-13 HDL cholesterol levels;HDL cholesterol; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg12152193 chr5:175954583 RNF44 0.42 6.22 0.32 1.47e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs12971120 0.891 rs11151961 chr18:72177340 C/T cg26446133 chr18:72167187 CNDP2 -0.79 -14.23 -0.61 2e-36 Refractive error; LIHC cis rs1728785 1.000 rs1170433 chr16:68606081 A/G cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs2073300 1.000 rs6114126 chr20:23452127 A/T cg12062639 chr20:23401060 NAPB 0.81 9.62 0.46 1.56e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6918586 0.615 rs198824 chr6:26122783 T/C cg18357526 chr6:26021779 HIST1H4A -0.59 -8.88 -0.43 3.85e-17 Schizophrenia; LIHC cis rs6088580 0.634 rs4911420 chr20:32998654 A/G cg08999081 chr20:33150536 PIGU -0.66 -13.01 -0.58 1.08e-31 Glomerular filtration rate (creatinine); LIHC cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg25072359 chr17:41440525 NA 0.38 6.1 0.31 2.85e-9 Menopause (age at onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21044577 chr13:111364847 ING1 0.47 6.84 0.35 3.68e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2625529 0.824 rs4777480 chr15:72328997 A/C cg16672083 chr15:72433130 SENP8 -0.31 -5.93 -0.31 7.22e-9 Red blood cell count; LIHC cis rs12464559 1.000 rs12464559 chr2:152597660 G/A cg01189475 chr2:152685088 ARL5A 0.67 6.77 0.34 5.68e-11 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs798554 0.836 rs2260230 chr7:2822986 T/A cg04166393 chr7:2884313 GNA12 0.44 6.17 0.32 1.93e-9 Height; LIHC cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.1 -0.44 7.39e-18 Bipolar disorder; LIHC cis rs8017423 0.647 rs4904677 chr14:90819245 C/T cg04374321 chr14:90722782 PSMC1 -0.5 -7.26 -0.37 2.64e-12 Mortality in heart failure; LIHC cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg10546459 chr2:36825355 FEZ2 0.61 7.79 0.39 8.19e-14 Height; LIHC cis rs763121 0.853 rs1056610 chr22:39080078 C/T cg06022373 chr22:39101656 GTPBP1 -0.75 -15.34 -0.64 8.83e-41 Menopause (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05264915 chr2:210867333 RPE 0.55 6.69 0.34 9.21e-11 Hepatitis; LIHC cis rs1862618 0.671 rs2591958 chr5:56239369 C/G cg12311346 chr5:56204834 C5orf35 0.45 6.13 0.31 2.48e-9 Initial pursuit acceleration; LIHC cis rs9916302 0.808 rs12943928 chr17:37611330 G/A cg03013999 chr17:37608204 MED1 0.35 5.93 0.31 7.47e-9 Glomerular filtration rate (creatinine); LIHC cis rs3096299 0.781 rs2170839 chr16:89409452 C/G cg08822215 chr16:89438651 ANKRD11 -0.42 -6.61 -0.34 1.52e-10 Multiple myeloma (IgH translocation); LIHC cis rs6977660 1.000 rs4719584 chr7:19823388 T/C cg07541023 chr7:19748670 TWISTNB 0.37 5.85 0.3 1.13e-8 Thyroid stimulating hormone; LIHC cis rs208515 0.525 rs12204706 chr6:66669930 A/G cg07460842 chr6:66804631 NA -0.74 -8.63 -0.42 2.37e-16 Exhaled nitric oxide levels; LIHC cis rs7786877 0.761 rs11772705 chr7:100298904 T/C cg16850897 chr7:100343110 ZAN -0.39 -5.94 -0.31 7.02e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10540 1.000 rs35874808 chr11:506442 G/T cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.22e-11 Body mass index; LIHC cis rs908922 0.676 rs11205014 chr1:152483634 C/T cg20991723 chr1:152506922 NA 0.57 10.25 0.48 1.13e-21 Hair morphology; LIHC cis rs7617773 0.780 rs71323395 chr3:48374077 G/A cg11946769 chr3:48343235 NME6 0.92 11.74 0.54 5.69e-27 Coronary artery disease; LIHC cis rs2832191 1.000 rs2832191 chr21:30489300 A/C cg24692254 chr21:30365293 RNF160 -0.62 -10.78 -0.5 1.64e-23 Dental caries; LIHC cis rs17685 0.712 rs10235086 chr7:75833138 G/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.37 -5.99 -0.31 5.32e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs875971 0.862 rs1695820 chr7:65844563 G/A cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03634887 chr16:66730948 CMTM4 0.46 6.41 0.33 4.9e-10 Pancreatic cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13131519 chr7:127032423 ZNF800 0.45 6.31 0.32 8.73e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.967 rs6575117 chr14:90715412 G/A cg14092571 chr14:90743983 NA -0.38 -6.04 -0.31 4.12e-9 Mortality in heart failure; LIHC trans rs6598955 0.572 rs6598951 chr1:26592714 G/T cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.59 -0.42 3.07e-16 Obesity-related traits; LIHC cis rs7772486 0.654 rs1011597 chr6:146075672 A/C cg13319975 chr6:146136371 FBXO30 0.35 5.87 0.3 1.03e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2997447 0.761 rs2783637 chr1:26439226 C/T cg19633962 chr1:26362018 EXTL1 -0.51 -5.74 -0.3 2.06e-8 QRS complex (12-leadsum); LIHC cis rs523522 0.962 rs3213565 chr12:120992401 C/T cg12219531 chr12:120966889 COQ5 0.68 13.4 0.59 3.38e-33 High light scatter reticulocyte count; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg12830327 chr11:85339628 TMEM126B;DLG2 -0.45 -6.59 -0.34 1.67e-10 Triglycerides; LIHC cis rs35306767 0.953 rs12357633 chr10:957246 C/T cg20503657 chr10:835505 NA 1.09 11.36 0.52 1.33e-25 Eosinophil percentage of granulocytes; LIHC cis rs9527 1.000 rs4919690 chr10:104616500 C/T cg15744005 chr10:104629667 AS3MT 0.4 7.31 0.37 1.95e-12 Arsenic metabolism; LIHC cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs9640161 0.711 rs3735170 chr7:150034184 T/C cg17279839 chr7:150038598 RARRES2 0.59 11.97 0.54 7.99e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs708547 0.874 rs1718837 chr4:57871203 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.6 8.68 0.42 1.68e-16 Response to bleomycin (chromatid breaks); LIHC cis rs9309711 0.643 rs4535074 chr2:3481637 A/G cg04359351 chr2:3481828 TTC15 0.29 6.17 0.32 1.88e-9 Neurofibrillary tangles; LIHC cis rs801193 0.773 rs801207 chr7:66020590 T/C cg14393609 chr7:65229607 NA -0.35 -5.71 -0.3 2.4e-8 Aortic root size; LIHC cis rs4819052 0.851 rs1999334 chr21:46670457 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.63 9.79 0.47 4.13e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs6885147 1.000 rs16893468 chr5:64467770 A/G cg27019278 chr4:101438804 EMCN 0.68 6.4 0.33 5.17e-10 Body mass index (change over time) in lung cancer or chronic obstructive pulmonary disease; LIHC cis rs1336900 0.641 rs6587756 chr1:150546865 A/T cg17724175 chr1:150552817 MCL1 -0.55 -10.83 -0.51 1.07e-23 Blood protein levels; LIHC cis rs589448 0.933 rs2249093 chr12:69753512 G/C cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 1.02e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg21782813 chr7:2030301 MAD1L1 0.42 6.88 0.35 2.9100000000000002e-11 Bipolar disorder and schizophrenia; LIHC cis rs11148252 1.000 rs11148252 chr13:53009048 C/T cg00495681 chr13:53174319 NA 0.4 6.58 0.34 1.76e-10 Lewy body disease; LIHC cis rs2070433 0.904 rs8130209 chr21:47925984 T/C cg12379764 chr21:47803548 PCNT 0.6 8.76 0.43 9.25e-17 Lymphocyte counts; LIHC cis rs7520050 0.966 rs12144263 chr1:46352446 G/A cg03146154 chr1:46216737 IPP -0.39 -6.46 -0.33 3.65e-10 Red blood cell count;Reticulocyte count; LIHC cis rs908922 0.676 rs493133 chr1:152493875 G/C cg23254163 chr1:152506842 NA 0.23 5.95 0.31 6.79e-9 Hair morphology; LIHC cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg18404041 chr3:52824283 ITIH1 -0.55 -8.91 -0.43 3.01e-17 Bipolar disorder; LIHC cis rs10197940 0.532 rs13425170 chr2:152387112 A/C cg19508488 chr2:152266495 RIF1 0.52 7.05 0.36 9.94e-12 Lung cancer; LIHC cis rs17106184 1.000 rs112780433 chr1:51401419 C/T cg07174182 chr1:51127561 FAF1 -0.74 -7.94 -0.39 2.99e-14 Type 2 diabetes; LIHC cis rs986417 1.000 rs6573318 chr14:61087985 A/G cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg25204440 chr1:209979598 IRF6 0.49 8.06 0.4 1.28e-14 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC cis rs10751667 0.666 rs10902243 chr11:949900 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.16 0.48 2.3e-21 Alzheimer's disease (late onset); LIHC cis rs875971 0.862 rs778697 chr7:65870426 G/A cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg08015704 chr19:12868765 BEST2 -0.47 -6.18 -0.32 1.83e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs12824058 0.831 rs4759658 chr12:130815872 C/T cg24229701 chr12:130821962 PIWIL1 0.44 6.77 0.34 5.55e-11 Menopause (age at onset); LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.765 rs17708262 chr2:99696313 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.35 -0.41 1.74e-15 Chronic sinus infection; LIHC trans rs2262909 0.962 rs4932952 chr19:22246788 G/A cg17074339 chr11:11642133 GALNTL4 0.4 6.09 0.31 3.09e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs1008375 1.000 rs28545485 chr4:17645376 C/T cg02297831 chr4:17616191 MED28 0.49 7.76 0.39 9.95e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9457247 0.765 rs6900701 chr6:167434112 A/G cg12798992 chr6:167411361 FGFR1OP 0.49 7.5 0.38 5.51e-13 Crohn's disease; LIHC cis rs1552244 0.882 rs55840655 chr3:10042690 C/T cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs2839627 0.561 rs7281655 chr21:44269743 A/G cg03543861 chr21:44258195 NA 0.52 8.63 0.42 2.35e-16 Information processing speed; LIHC cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.15 -0.44 5.33e-18 Bipolar disorder; LIHC cis rs9902453 0.868 rs7212162 chr17:28321328 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.87 0.6 5.03e-35 Coffee consumption (cups per day); LIHC cis rs2282802 0.685 rs1347143 chr5:139669386 A/G cg26211634 chr5:139558579 C5orf32 -0.37 -5.74 -0.3 2.07e-8 Intelligence (multi-trait analysis); LIHC cis rs11628318 0.617 rs11626481 chr14:103086356 A/G cg01864069 chr14:103024347 NA -0.49 -7.4 -0.37 1.04e-12 Platelet count; LIHC cis rs6963495 0.872 rs73190193 chr7:105164852 A/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs1664789 0.743 rs1694104 chr5:53263103 C/T ch.5.1024479R chr5:53302184 ARL15 0.44 6.63 0.34 1.28e-10 Waist circumference adjusted for body mass index; LIHC cis rs8077889 0.956 rs17742347 chr17:41846468 A/G cg26893861 chr17:41843967 DUSP3 -1.02 -11.32 -0.52 1.91e-25 Triglycerides; LIHC cis rs861318 0.702 rs6940 chr1:159024668 A/T cg11003133 chr1:159046391 AIM2 -0.33 -6.38 -0.33 5.77e-10 Obesity-related traits; LIHC cis rs875971 0.862 rs6962717 chr7:65883735 G/A cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs546131 0.642 rs11600239 chr11:34821699 G/A cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.36 -0.33 6.29e-10 Lung disease severity in cystic fibrosis; LIHC cis rs2289583 0.642 rs67624860 chr15:75391557 A/G cg15902774 chr15:75289873 SCAMP5 0.34 5.96 0.31 6.21e-9 Systemic lupus erythematosus; LIHC cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6964587 0.869 rs34791781 chr7:91532720 C/T cg17063962 chr7:91808500 NA -0.98 -18.7 -0.71 3.06e-54 Breast cancer; LIHC cis rs79149102 0.579 rs7342591 chr15:75306863 C/T cg17294928 chr15:75287854 SCAMP5 0.5 6.73 0.34 7.34e-11 Lung cancer; LIHC cis rs929354 0.742 rs7806775 chr7:156947199 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg06558623 chr16:89946397 TCF25 0.96 15.09 0.63 8.93e-40 Skin colour saturation; LIHC trans rs916888 0.773 rs199447 chr17:44812188 C/T cg16836995 chr17:43662488 NA -0.77 -7.89 -0.39 4.06e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25387593 chr11:118927868 HYOU1 0.51 6.88 0.35 2.88e-11 Lung function (FEV1/FVC); LIHC cis rs8062405 0.656 rs7189927 chr16:28913787 T/C cg00204512 chr16:28754710 NA -0.35 -6.14 -0.32 2.29e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12188164 0.561 rs2721010 chr5:456915 A/G cg07599136 chr5:415885 AHRR 0.39 6.66 0.34 1.1e-10 Cystic fibrosis severity; LIHC cis rs7772486 0.603 rs2223411 chr6:146028767 T/C cg23711669 chr6:146136114 FBXO30 -0.64 -10.16 -0.48 2.31e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs6728642 0.908 rs17842456 chr2:98014319 C/T cg26665480 chr2:98280029 ACTR1B 0.65 6.42 0.33 4.46e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC trans rs208520 0.690 rs12213575 chr6:66735989 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.95 0.44 2.35e-17 Exhaled nitric oxide output; LIHC cis rs311392 0.554 rs689591 chr8:55096050 A/G cg11783602 chr8:55087084 NA -0.31 -6.16 -0.32 2.05e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs782590 0.967 rs17278044 chr2:55748217 G/C cg03859395 chr2:55845619 SMEK2 0.92 15.71 0.65 3.07e-42 Metabolic syndrome; LIHC cis rs950169 0.960 rs35159785 chr15:84804014 G/A cg17507749 chr15:85114479 UBE2QP1 0.77 7.95 0.39 2.82e-14 Schizophrenia; LIHC cis rs3814244 0.528 rs10878723 chr12:68399273 A/G cg15249341 chr12:68405565 NA -0.32 -6.24 -0.32 1.33e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg00280220 chr17:61926910 NA 0.43 6.69 0.34 9.03e-11 Prudent dietary pattern; LIHC cis rs4663866 0.901 rs35713061 chr2:239183774 C/T cg16914508 chr2:239161102 PER2 0.8 5.84 0.3 1.23e-8 Irritable bowel syndrome; LIHC cis rs12549902 0.800 rs4736999 chr8:41506152 C/G cg21772509 chr8:41503840 NKX6-3 0.39 6.36 0.33 6.33e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.94 19.28 0.72 1.38e-56 Height; LIHC cis rs208520 0.661 rs150263 chr6:66777620 T/C cg07460842 chr6:66804631 NA -0.79 -8.86 -0.43 4.48e-17 Exhaled nitric oxide output; LIHC cis rs10794720 0.748 rs11250275 chr10:1171823 A/G cg08668510 chr10:1095578 IDI1 -0.82 -5.83 -0.3 1.29e-8 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease; LIHC cis rs6733011 0.508 rs4851173 chr2:99520608 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.87 -0.35 3.1e-11 Bipolar disorder; LIHC trans rs1005277 0.577 rs4934906 chr10:38015028 C/T cg27523141 chr10:43048294 ZNF37B 0.38 6.61 0.34 1.45e-10 Extrinsic epigenetic age acceleration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22588542 chr2:228190772 MFF -0.43 -6.06 -0.31 3.59e-9 Pancreatic cancer; LIHC cis rs6840360 0.615 rs4696097 chr4:152479765 C/T cg22705602 chr4:152727874 NA 0.33 6.54 0.33 2.19e-10 Intelligence (multi-trait analysis); LIHC cis rs79149102 0.579 rs74023936 chr15:75362084 C/T cg17294928 chr15:75287854 SCAMP5 -0.46 -5.83 -0.3 1.3e-8 Lung cancer; LIHC cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Bipolar disorder; LIHC cis rs4845459 0.967 rs1886734 chr1:152591142 A/C cg20634798 chr1:152595351 LCE3A -0.32 -6.2 -0.32 1.63e-9 Psoriasis; LIHC cis rs2180341 0.924 rs6930849 chr6:127630963 A/T cg24812749 chr6:127587940 RNF146 1.07 16.09 0.66 9.4e-44 Breast cancer; LIHC cis rs6088580 0.524 rs2378251 chr20:33276750 C/T cg07148914 chr20:33460835 GGT7 -0.49 -6.95 -0.35 1.87e-11 Glomerular filtration rate (creatinine); LIHC cis rs2304069 0.954 rs1962603 chr5:149393006 G/T cg12661370 chr5:149340060 SLC26A2 0.51 6.13 0.31 2.49e-9 HIV-1 control; LIHC cis rs7312933 0.966 rs6582375 chr12:42423185 A/T cg17420585 chr12:42539391 GXYLT1 -0.36 -5.72 -0.3 2.33e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11676348 0.783 rs13035513 chr2:218960680 C/T cg00012203 chr2:219082015 ARPC2 -0.55 -7.64 -0.38 2.16e-13 Ulcerative colitis; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg00656387 chr3:40428638 ENTPD3 0.49 8.25 0.41 3.48e-15 Renal cell carcinoma; LIHC cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg07414643 chr4:187882934 NA 0.23 6.06 0.31 3.59e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4700695 0.668 rs253212 chr5:65497553 C/T cg21114390 chr5:65439923 SFRS12 -0.56 -7.97 -0.4 2.43e-14 Facial morphology (factor 19); LIHC trans rs61931739 0.500 rs7313094 chr12:34457508 T/C cg26384229 chr12:38710491 ALG10B 0.64 8.13 0.4 8.12e-15 Morning vs. evening chronotype; LIHC cis rs7635838 0.650 rs1375206 chr3:11339117 C/G cg00170343 chr3:11313890 ATG7 0.59 10.11 0.48 3.27e-21 HDL cholesterol; LIHC cis rs2749592 0.550 rs9733309 chr10:37882405 G/A cg00409905 chr10:38381863 ZNF37A 0.51 8.54 0.42 4.38e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg24549020 chr5:56110836 MAP3K1 0.49 6.34 0.32 7.22e-10 Initial pursuit acceleration; LIHC cis rs2370759 1.000 rs2370759 chr10:32634972 G/A cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs2463822 1.000 rs2513749 chr11:62105391 C/T cg06239285 chr11:62104954 ASRGL1 0.87 6.74 0.34 6.93e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs7220401 0.789 rs4794859 chr17:27962393 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.64 -9.59 -0.46 1.93e-19 Coronary artery disease; LIHC trans rs2262909 0.962 rs17459246 chr19:22278121 T/C cg05197062 chr11:11642011 GALNTL4 0.44 6.45 0.33 3.74e-10 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC trans rs3749237 1.000 rs4768 chr3:49758764 A/G cg21659725 chr3:3221576 CRBN 0.78 12.34 0.56 3.41e-29 Resting heart rate; LIHC cis rs11864453 0.713 rs7190995 chr16:72124157 A/G cg01557791 chr16:72042693 DHODH -0.47 -7.62 -0.38 2.58e-13 Fibrinogen levels; LIHC cis rs72627123 0.656 rs117129791 chr14:74520871 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.88 8.7 0.43 1.38e-16 Morning vs. evening chronotype; LIHC cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg04267008 chr7:1944627 MAD1L1 -0.55 -8.53 -0.42 4.75e-16 Schizophrenia; LIHC cis rs4423214 1.000 rs11606612 chr11:71164047 C/A cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC cis rs4713118 0.869 rs9283880 chr6:27715243 A/C cg20933634 chr6:27740509 NA 0.47 6.19 0.32 1.69e-9 Parkinson's disease; LIHC cis rs2153535 0.580 rs986060 chr6:8465428 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC trans rs7657257 1.000 rs16892283 chr4:15731534 A/G cg17675199 chr6:35436792 RPL10A -0.42 -6.57 -0.33 1.85e-10 Blood protein levels; LIHC cis rs9818758 0.545 rs11717978 chr3:48969036 T/A cg07636037 chr3:49044803 WDR6 -0.79 -7.76 -0.39 9.98e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1144333 1.000 rs17097841 chr1:76462641 T/A cg22875332 chr1:76189707 ACADM 0.4 6.24 0.32 1.26e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2228479 0.702 rs11076621 chr16:89837927 A/G cg05185784 chr16:90016020 DEF8 -0.46 -5.72 -0.3 2.27e-8 Skin colour saturation; LIHC cis rs2050392 0.762 rs306587 chr10:30722908 G/C cg25182066 chr10:30743637 MAP3K8 -0.5 -8.05 -0.4 1.37e-14 Inflammatory bowel disease; LIHC cis rs6840360 0.615 rs7669465 chr4:152609289 C/T cg22705602 chr4:152727874 NA -0.35 -7.39 -0.37 1.1e-12 Intelligence (multi-trait analysis); LIHC cis rs950169 0.959 rs12911210 chr15:84792083 A/C cg17507749 chr15:85114479 UBE2QP1 0.76 7.89 0.39 4.07e-14 Schizophrenia; LIHC cis rs9393777 0.513 rs6924727 chr6:26491234 A/G cg12826209 chr6:26865740 GUSBL1 0.68 8.14 0.4 7.54e-15 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs933688 1.000 rs1895448 chr5:90743854 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.62 0.69 6.85e-50 Smoking behavior; LIHC cis rs4845570 1.000 rs6683364 chr1:151746202 T/A cg07092448 chr1:151763213 TDRKH -0.72 -7.97 -0.4 2.33e-14 Coronary artery disease; LIHC cis rs2070488 0.689 rs6809352 chr3:38544349 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.73 -12.17 -0.55 1.47e-28 Electrocardiographic conduction measures; LIHC cis rs365132 1.000 rs353467 chr5:176445698 T/C cg16309518 chr5:176445507 NA -0.58 -11.34 -0.52 1.62e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs4819052 0.851 rs8131143 chr21:46671646 C/G cg22633049 chr21:46681294 NA 0.36 6.22 0.32 1.46e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1555322 0.505 rs591590 chr20:33866028 A/G cg08210727 chr20:33865349 NA -0.51 -5.9 -0.3 8.9e-9 Attention deficit hyperactivity disorder; LIHC cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg08888203 chr3:10149979 C3orf24 0.57 6.49 0.33 3.06e-10 Alzheimer's disease; LIHC cis rs6545883 0.894 rs7566035 chr2:61520815 C/T cg14146966 chr2:61757674 XPO1 -0.43 -7.32 -0.37 1.75e-12 Tuberculosis; LIHC cis rs763121 0.853 rs9610993 chr22:39042818 C/A cg14440974 chr22:39074834 NA -0.41 -6.65 -0.34 1.13e-10 Menopause (age at onset); LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg09455208 chr3:40491958 NA 0.39 7.91 0.39 3.67e-14 Renal cell carcinoma; LIHC cis rs35661897 0.764 rs67648943 chr2:227259665 C/A cg03426602 chr2:227312417 NA -0.56 -5.95 -0.31 6.58e-9 Urinary tract infection frequency; LIHC cis rs9549367 0.789 rs9604040 chr13:113910611 A/G cg18105134 chr13:113819100 PROZ 0.56 9.83 0.47 3.12e-20 Platelet distribution width; LIHC cis rs7487075 0.823 rs34472481 chr12:46836348 C/G cg11331445 chr12:47219877 SLC38A4 0.26 5.73 0.3 2.18e-8 Itch intensity from mosquito bite; LIHC cis rs7772486 0.764 rs9399569 chr6:146242942 C/T cg05347473 chr6:146136440 FBXO30 -0.35 -5.78 -0.3 1.71e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.503 rs5751156 chr22:42170025 A/G cg06634786 chr22:41940651 POLR3H 0.72 7.28 0.37 2.25e-12 Vitiligo; LIHC cis rs743757 1.000 rs743757 chr3:50476378 C/G cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.44 -6.18 -0.32 1.8e-9 Diastolic blood pressure; LIHC cis rs637571 0.780 rs677029 chr11:65683531 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.47 7.64 0.38 2.24e-13 Eosinophil percentage of white cells; LIHC cis rs11105298 0.891 rs10858851 chr12:89830870 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.63 -6.91 -0.35 2.34e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs4689592 0.503 rs10516184 chr4:7060959 C/T cg02503808 chr4:7069936 GRPEL1 0.78 11.01 0.51 2.56e-24 Monocyte percentage of white cells; LIHC cis rs875971 0.862 rs10250544 chr7:65766561 A/G cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs17384381 0.953 rs11161599 chr1:85795965 A/G cg16011679 chr1:85725395 C1orf52 -0.77 -8.5 -0.42 6.16e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg13699009 chr12:122356056 WDR66 0.6 9.23 0.45 2.82e-18 Mean corpuscular volume; LIHC cis rs11148252 0.574 rs3742297 chr13:53278067 T/C cg00495681 chr13:53174319 NA 0.7 12.6 0.56 3.78e-30 Lewy body disease; LIHC cis rs2439831 0.850 rs8023458 chr15:44080939 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.43 0.41 1.01e-15 Lung cancer in ever smokers; LIHC cis rs651907 0.535 rs13085776 chr3:101505507 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 10.09 0.48 3.86e-21 Colorectal cancer; LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg00091569 chr3:40428383 ENTPD3 0.39 6.57 0.33 1.82e-10 Renal cell carcinoma; LIHC cis rs2832191 0.545 rs2251381 chr21:30530692 T/G cg08807101 chr21:30365312 RNF160 0.52 7.53 0.38 4.66e-13 Dental caries; LIHC cis rs7542091 0.635 rs985431 chr1:210043948 A/T cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC trans rs10411161 0.810 rs76098421 chr19:52404645 T/C cg22319618 chr22:45562946 NUP50 -0.61 -7.18 -0.36 4.32e-12 Breast cancer; LIHC cis rs8064299 0.597 rs7210318 chr17:72783385 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.73 12.81 0.57 6.08e-31 Monocyte count; LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg10150615 chr22:24372951 LOC391322 -0.59 -8.48 -0.42 6.94e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6089584 0.566 rs6061401 chr20:60607482 G/A cg06108461 chr20:60628389 TAF4 -0.65 -9.17 -0.44 4.4e-18 Body mass index; LIHC cis rs6089584 0.586 rs4925216 chr20:60599923 G/A cg06108461 chr20:60628389 TAF4 -0.56 -7.37 -0.37 1.33e-12 Body mass index; LIHC cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg00343986 chr7:65444356 GUSB 0.43 6.06 0.31 3.68e-9 Aortic root size; LIHC cis rs10504229 0.679 rs1442125 chr8:58036258 A/C cg20607798 chr8:58055168 NA -0.44 -6.47 -0.33 3.42e-10 Developmental language disorder (linguistic errors); LIHC cis rs17826219 0.500 rs9891256 chr17:29072692 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.33 0.41 1.98e-15 Body mass index; LIHC cis rs3815700 0.920 rs10424732 chr19:33096487 C/T cg02997394 chr19:33096574 ANKRD27 0.75 9.83 0.47 2.94e-20 Eosinophilic esophagitis; LIHC cis rs6424115 0.964 rs2473375 chr1:24136545 C/T cg10978503 chr1:24200527 CNR2 0.38 8.97 0.44 1.93e-17 Immature fraction of reticulocytes; LIHC trans rs2243480 1.000 rs1618893 chr7:66096119 C/T cg07424592 chr7:64974309 NA 0.65 7.92 0.39 3.35e-14 Diabetic kidney disease; LIHC cis rs1577917 0.839 rs6929514 chr6:86525768 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.6 -0.38 2.92e-13 Response to antipsychotic treatment; LIHC cis rs10463316 0.862 rs10062928 chr5:150768355 C/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.68 -0.34 9.73e-11 Metabolite levels (Pyroglutamine); LIHC cis rs72781680 0.898 rs72786279 chr2:24063266 C/T cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg04944784 chr2:26401820 FAM59B -0.71 -9.12 -0.44 6.46e-18 Gut microbiome composition (summer); LIHC trans rs4714291 1.000 rs847752 chr6:40034557 T/C cg02267698 chr19:7991119 CTXN1 0.4 6.33 0.32 7.66e-10 Strep throat; LIHC cis rs9318086 0.712 rs12875437 chr13:24453956 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.55 10.94 0.51 4.28e-24 Myopia (pathological); LIHC cis rs1577917 0.917 rs13196576 chr6:86534066 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.11 -0.4 8.96e-15 Response to antipsychotic treatment; LIHC trans rs208520 0.754 rs7753158 chr6:66875633 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.71 -7.69 -0.38 1.58e-13 Exhaled nitric oxide output; LIHC cis rs11583043 1.000 rs17100939 chr1:101443701 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 8.3 0.41 2.45e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7534824 0.625 rs12568338 chr1:101500622 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.72 7.23 0.36 3.18e-12 Refractive astigmatism; LIHC cis rs748404 0.697 rs554001 chr15:43551919 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.43 6.55 0.33 2.08e-10 Lung cancer; LIHC cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg06640241 chr16:89574553 SPG7 0.84 15.18 0.63 3.78e-40 Multiple myeloma (IgH translocation); LIHC cis rs2204008 0.774 rs11495721 chr12:38337224 A/C cg26384229 chr12:38710491 ALG10B 0.57 7.78 0.39 8.78e-14 Bladder cancer; LIHC cis rs11190604 1.000 rs4244338 chr10:102272802 A/G cg07080220 chr10:102295463 HIF1AN 0.56 8.03 0.4 1.63e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs875971 0.767 rs12668005 chr7:65909021 T/C cg11764359 chr7:65958608 NA 0.76 12.78 0.57 7.43e-31 Aortic root size; LIHC cis rs2380220 1.000 rs9400318 chr6:95972381 T/A cg04719120 chr6:96025338 MANEA 0.64 6.77 0.34 5.48e-11 Behavioural disinhibition (generation interaction); LIHC cis rs7945718 0.775 rs10500759 chr11:12822588 A/G cg25843174 chr11:12811716 TEAD1 -0.3 -6.93 -0.35 2.07e-11 Educational attainment (years of education); LIHC cis rs7552404 1.000 rs4949875 chr1:76173080 G/A cg10523679 chr1:76189770 ACADM 0.64 8.7 0.43 1.43e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4409675 0.576 rs2078328 chr1:28224976 A/G cg23691781 chr1:28212827 C1orf38 0.31 7.46 0.37 7.21e-13 Corneal astigmatism; LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg06873352 chr17:61820015 STRADA -0.69 -11.58 -0.53 2.1e-26 Prudent dietary pattern; LIHC cis rs1371867 0.875 rs1788176 chr8:101332112 A/G cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC cis rs3749237 0.595 rs1464566 chr3:49459376 T/C cg02487422 chr3:49467188 NICN1 0.42 6.57 0.33 1.9e-10 Resting heart rate; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg16103275 chr6:290800 DUSP22 0.5 6.44 0.33 4.07e-10 Menopause (age at onset); LIHC cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg00684032 chr4:1343700 KIAA1530 0.51 7.39 0.37 1.15e-12 Obesity-related traits; LIHC cis rs5753618 0.583 rs5749279 chr22:31854209 A/G cg02404636 chr22:31891804 SFI1 0.34 6.02 0.31 4.45e-9 Colorectal cancer; LIHC cis rs7208859 0.673 rs9915139 chr17:29158515 A/G cg13385521 chr17:29058706 SUZ12P 0.81 7.9 0.39 3.85e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2573652 1.000 rs1469829 chr15:100517332 A/G cg09918751 chr15:100517450 ADAMTS17 -0.85 -16.75 -0.67 2.06e-46 Height; LIHC cis rs6466055 0.669 rs2299304 chr7:104771857 T/C cg04380332 chr7:105027541 SRPK2 -0.33 -6.3 -0.32 8.99e-10 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13077517 chr20:2082435 STK35 0.41 6.12 0.31 2.59e-9 Lung function (FEV1/FVC); LIHC cis rs4665809 0.938 rs6742226 chr2:26342537 A/G cg04944784 chr2:26401820 FAM59B -0.68 -8.7 -0.43 1.44e-16 Gut microbiome composition (summer); LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.64 0.38 2.16e-13 Prudent dietary pattern; LIHC cis rs7523273 0.925 rs6540443 chr1:208002010 T/A cg22525895 chr1:207977042 MIR29B2 -0.69 -10.59 -0.5 7.74e-23 Schizophrenia; LIHC cis rs2479724 0.870 rs7766817 chr6:41918104 T/A cg17623882 chr6:41773611 USP49 -0.5 -7.4 -0.37 1.09e-12 Menarche (age at onset); LIHC cis rs7312933 0.558 rs11181501 chr12:42822671 G/A cg17420585 chr12:42539391 GXYLT1 -0.36 -5.92 -0.3 7.91e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs273218 0.590 rs156828 chr5:53364230 C/T ch.5.1024479R chr5:53302184 ARL15 0.56 9.86 0.47 2.36e-20 Migraine; LIHC trans rs71658797 0.536 rs9324162 chr1:77954804 A/G cg04606550 chr5:14226569 TRIO 0.41 6.18 0.32 1.83e-9 Lung cancer in ever smokers;Lung cancer;Lung adenocarcinoma; LIHC cis rs12744310 0.943 rs7521544 chr1:41772126 G/A cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11676855 0.924 rs11680626 chr2:235927511 A/T cg14917874 chr2:235941519 SH3BP4 -0.6 -8.46 -0.42 8.07e-16 Dialysis-related mortality; LIHC cis rs17826219 0.568 rs9898097 chr17:29072672 T/G cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Body mass index; LIHC cis rs1865721 0.656 rs724765 chr18:73139794 A/G cg26385618 chr18:73139727 C18orf62 -0.29 -8.35 -0.41 1.67e-15 Intelligence; LIHC cis rs7107174 1.000 rs2511185 chr11:77982496 C/A cg02023728 chr11:77925099 USP35 0.45 8.65 0.42 2.05e-16 Testicular germ cell tumor; LIHC cis rs896854 0.818 rs896855 chr8:95959808 A/G cg13393036 chr8:95962371 TP53INP1 -0.4 -9.53 -0.46 2.98e-19 Type 2 diabetes; LIHC cis rs2976388 1.000 rs2920297 chr8:143763083 A/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs881375 0.934 rs2159778 chr9:123678129 G/A cg14580859 chr9:123691850 NA 0.35 6.17 0.32 1.95e-9 Rheumatoid arthritis; LIHC cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg04025307 chr7:1156635 C7orf50 0.67 11.68 0.53 9.55e-27 Longevity;Endometriosis; LIHC cis rs11608355 0.515 rs7311488 chr12:109930905 C/G cg05360138 chr12:110035743 NA -0.95 -10.85 -0.51 9.18e-24 Neuroticism; LIHC cis rs7412746 0.611 rs4970931 chr1:150910727 G/A cg15448220 chr1:150897856 SETDB1 0.39 6.25 0.32 1.22e-9 Melanoma; LIHC cis rs59901009 0.863 rs2278634 chr11:10184463 C/A cg01453529 chr11:10209919 SBF2 -0.33 -6.49 -0.33 2.99e-10 Hematocrit;Hemoglobin concentration; LIHC cis rs4727027 0.727 rs3801980 chr7:148878620 T/A cg23583168 chr7:148888333 NA -0.73 -9.49 -0.46 4.15e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.83 8.67 0.42 1.78e-16 Platelet count; LIHC cis rs651907 0.535 rs17347156 chr3:101504674 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.66 10.71 0.5 2.83e-23 Colorectal cancer; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg25461793 chr19:17212553 MYO9B 0.42 6.5 0.33 2.87e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7258015 1.000 rs7250300 chr19:10448660 C/A cg13981319 chr19:10446556 ICAM3 0.45 6.57 0.33 1.9e-10 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg02990361 chr1:107599529 PRMT6 0.64 10.66 0.5 4.15e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs988712 0.705 rs4923461 chr11:27656910 A/G cg18117895 chr11:27722066 BDNF 0.45 6.14 0.32 2.3e-9 Obesity; LIHC cis rs7584330 0.822 rs13390494 chr2:238388792 G/A cg14458575 chr2:238380390 NA 0.37 5.98 0.31 5.66e-9 Prostate cancer; LIHC cis rs4073582 0.555 rs521109 chr11:66030948 G/A cg14036092 chr11:66035641 RAB1B 0.45 6.72 0.34 7.4e-11 Gout; LIHC cis rs9388451 0.839 rs4897155 chr6:126095144 C/A cg06289844 chr6:126071538 HEY2 0.34 5.96 0.31 6.33e-9 Brugada syndrome; LIHC cis rs17253792 0.822 rs77250916 chr14:56042208 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs332507 0.830 rs3772789 chr3:124395607 A/G cg05980111 chr3:124395277 KALRN 0.45 6.99 0.35 1.49e-11 Plateletcrit; LIHC cis rs2576037 0.523 rs4890705 chr18:44509758 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.72 11.56 0.53 2.55e-26 Personality dimensions; LIHC cis rs25645 0.502 rs9895948 chr17:38108363 T/C cg17344932 chr17:38183730 MED24;SNORD124 -0.47 -7.06 -0.36 9.28e-12 Myeloid white cell count; LIHC cis rs919433 0.679 rs67492914 chr2:198523402 T/G cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs34172651 0.876 rs964782 chr16:24811740 T/C cg04756594 chr16:24857601 SLC5A11 0.48 7.5 0.38 5.38e-13 Intelligence (multi-trait analysis); LIHC cis rs7617773 0.780 rs11720026 chr3:48377921 T/C cg11946769 chr3:48343235 NME6 0.93 11.81 0.54 3.03e-27 Coronary artery disease; LIHC cis rs12413816 0.784 rs11258560 chr10:13770137 A/G cg16485048 chr10:13749193 FRMD4A 0.49 6.62 0.34 1.36e-10 Red cell distribution width; LIHC cis rs7917772 0.505 rs61869211 chr10:104449836 A/G cg22532475 chr10:104410764 TRIM8 -0.37 -6.5 -0.33 2.93e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs782590 0.837 rs782585 chr2:55922930 C/T cg18811423 chr2:55921094 PNPT1 1.05 17.36 0.68 7.23e-49 Metabolic syndrome; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00802484 chr4:39773226 UBE2K 0.46 6.74 0.34 6.82e-11 Bilirubin levels; LIHC cis rs3770081 1.000 rs60479377 chr2:86283948 A/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.57 8.85 0.43 4.86e-17 Facial emotion recognition (sad faces); LIHC cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg07424592 chr7:64974309 NA 0.75 8.79 0.43 7.66e-17 Diabetic kidney disease; LIHC cis rs3736485 0.932 rs4775966 chr15:51913788 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.15 -0.32 2.19e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2637266 0.875 rs2395409 chr10:78381004 A/G cg18941641 chr10:78392320 NA 0.27 5.73 0.3 2.2e-8 Pulmonary function; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg07466437 chr6:8086756 EEF1E1;SCARNA27 0.37 6.07 0.31 3.49e-9 Immature fraction of reticulocytes; LIHC cis rs9858542 0.953 rs6766131 chr3:49538932 T/C cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4665809 1.000 rs750452 chr2:26324995 G/A cg27170947 chr2:26402098 FAM59B -0.65 -8.28 -0.41 2.75e-15 Gut microbiome composition (summer); LIHC cis rs1862618 0.620 rs2591967 chr5:56233551 C/G cg12311346 chr5:56204834 C5orf35 0.46 6.28 0.32 1.02e-9 Initial pursuit acceleration; LIHC cis rs655641 0.953 rs472618 chr11:85662839 T/G cg09030501 chr11:85779252 PICALM -0.49 -5.94 -0.31 6.86e-9 Platelet count; LIHC trans rs1875517 0.510 rs11721241 chr3:117329656 A/C cg23682007 chr1:167523064 CREG1 0.34 6.29 0.32 9.87e-10 Waist circumference; LIHC cis rs34375054 0.687 rs35540170 chr12:125669122 C/G cg25124228 chr12:125621409 AACS -0.44 -7.06 -0.36 9.1e-12 Post bronchodilator FEV1/FVC ratio; LIHC cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg25894440 chr7:65020034 NA -0.53 -6.17 -0.32 1.93e-9 Diabetic kidney disease; LIHC cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg13866156 chr1:1669148 SLC35E2 -0.61 -10.79 -0.5 1.53e-23 Body mass index; LIHC cis rs887797 0.518 rs8075979 chr17:64576138 C/T cg27019712 chr17:64599478 PRKCA -0.34 -5.92 -0.3 7.9e-9 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17376456 0.877 rs28637444 chr5:93495548 C/T cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.58e-21 Diabetic retinopathy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14197205 chr17:28256862 EFCAB5;SSH2 0.42 6.12 0.31 2.6e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs965469 0.724 rs6037527 chr20:3254412 T/G cg25506879 chr20:3388711 C20orf194 -0.52 -6.46 -0.33 3.58e-10 IFN-related cytopenia; LIHC cis rs10781543 0.817 rs1128874 chr9:139323424 T/C cg14169450 chr9:139327907 INPP5E 0.36 5.79 0.3 1.62e-8 Monocyte percentage of white cells; LIHC cis rs78456975 0.527 rs72778003 chr2:1571487 G/A cg01028140 chr2:1542097 TPO -0.42 -6.66 -0.34 1.08e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1443512 0.773 rs2366146 chr12:54331002 G/A cg12374095 chr12:54320830 NA 0.44 6.36 0.33 6.39e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs831571 0.695 rs73120926 chr3:64036950 G/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.51 -5.87 -0.3 1.04e-8 Type 2 diabetes; LIHC cis rs10791097 0.739 rs4936120 chr11:130723452 G/A cg14779329 chr11:130786720 SNX19 0.38 5.88 0.3 9.87e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7937682 0.883 rs1784776 chr11:111472392 C/T cg09085632 chr11:111637200 PPP2R1B -0.93 -11.29 -0.52 2.55e-25 Primary sclerosing cholangitis; LIHC cis rs116248771 0.549 rs9811858 chr3:158443093 T/C cg16708174 chr3:158430962 RARRES1 0.71 9.47 0.46 4.69e-19 diarrhoeal disease at age 2; LIHC cis rs9457247 0.515 rs1951459 chr6:167402536 G/A cg23791538 chr6:167370224 RNASET2 0.76 14.06 0.61 9.19e-36 Crohn's disease; LIHC cis rs332507 0.601 rs13064734 chr3:124374940 C/T cg05980111 chr3:124395277 KALRN 0.32 6.21 0.32 1.57e-9 Plateletcrit; LIHC cis rs9341808 0.718 rs9343978 chr6:80971978 A/G cg08355045 chr6:80787529 NA 0.35 7.34 0.37 1.55e-12 Sitting height ratio; LIHC cis rs2439831 1.000 rs527921 chr15:43770416 G/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.67 -8.67 -0.42 1.81e-16 Lung cancer in ever smokers; LIHC cis rs2439831 0.717 rs9806227 chr15:43680115 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.97 0.51 3.47e-24 Lung cancer in ever smokers; LIHC cis rs875971 1.000 rs6956179 chr7:65806659 C/T cg11764359 chr7:65958608 NA -0.91 -16.94 -0.68 3.63e-47 Aortic root size; LIHC cis rs60871478 1.000 rs4720917 chr7:806998 C/G cg13844804 chr7:814759 HEATR2 0.44 5.95 0.31 6.72e-9 Cerebrospinal P-tau181p levels; LIHC cis rs7095607 0.606 rs10998015 chr10:69959624 A/G cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.66e-9 Lung function (FVC); LIHC cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg17971929 chr21:40555470 PSMG1 -0.4 -6.05 -0.31 3.79e-9 Menarche (age at onset); LIHC cis rs704795 0.651 rs11693959 chr2:27574159 T/C cg27432699 chr2:27873401 GPN1 -0.63 -6.11 -0.31 2.64e-9 Menopause (age at onset); LIHC cis rs12477438 0.765 rs10193039 chr2:99692373 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.69 -9.89 -0.47 1.95e-20 Chronic sinus infection; LIHC cis rs7312933 0.934 rs11181289 chr12:42402342 C/T cg01256987 chr12:42539512 GXYLT1 -0.39 -6.32 -0.32 8.07e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs3857067 0.806 rs7654565 chr4:95112939 G/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.68 0.57 1.91e-30 Alzheimer's disease; LIHC cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg18230493 chr5:56204884 C5orf35 -0.44 -6.12 -0.31 2.62e-9 Initial pursuit acceleration; LIHC cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg03806693 chr22:41940476 POLR3H -0.97 -9.78 -0.47 4.4e-20 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03261162 chr17:79791653 DYSFIP1;FAM195B 0.46 6.28 0.32 1.05e-9 Pancreatic cancer; LIHC cis rs8062405 1.000 rs7498665 chr16:28883241 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7296418 0.630 rs11608305 chr12:123791165 C/G cg05973401 chr12:123451056 ABCB9 0.41 6.31 0.32 8.89e-10 Platelet count; LIHC cis rs9814567 1.000 rs2177601 chr3:134245434 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9905704 0.624 rs34718875 chr17:57072461 G/A cg12560992 chr17:57184187 TRIM37 0.66 9.77 0.47 4.67e-20 Testicular germ cell tumor; LIHC cis rs4819052 0.765 rs2838868 chr21:46714641 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.55 -7.04 -0.36 1.05e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7412746 0.658 rs3768015 chr1:150812954 C/T cg15448220 chr1:150897856 SETDB1 0.39 5.86 0.3 1.08e-8 Melanoma; LIHC cis rs3782089 0.744 rs11545200 chr11:65319751 G/A cg00206168 chr11:65308501 LTBP3 1.09 7.67 0.38 1.8e-13 Height; LIHC cis rs9513627 0.831 rs9582301 chr13:100125814 C/T cg25919922 chr13:100150906 NA -0.76 -6.66 -0.34 1.07e-10 Obesity-related traits; LIHC cis rs593982 1.000 rs593982 chr11:65513107 T/C cg08755490 chr11:65554678 OVOL1 0.55 8.54 0.42 4.46e-16 Atopic dermatitis; LIHC cis rs66887589 1.000 rs66887589 chr4:120509279 T/C cg09307838 chr4:120376055 NA -0.49 -7.34 -0.37 1.58e-12 Diastolic blood pressure; LIHC cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 11.6 0.53 1.85e-26 Alzheimer's disease; LIHC cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg12463550 chr7:65579703 CRCP 0.68 7.32 0.37 1.74e-12 Diabetic kidney disease; LIHC cis rs7917772 0.604 rs7908249 chr10:104373300 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.03e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs4332037 1.000 rs6947019 chr7:1950337 G/A cg11693508 chr17:37793320 STARD3 0.69 7.23 0.36 3.17e-12 Bipolar disorder; LIHC cis rs11098499 0.954 rs28572238 chr4:120316686 T/G cg09307838 chr4:120376055 NA 0.77 11.88 0.54 1.75e-27 Corneal astigmatism; LIHC cis rs11098499 1.000 rs7659194 chr4:120207147 T/G cg09307838 chr4:120376055 NA 0.71 10.58 0.5 8.06e-23 Corneal astigmatism; LIHC cis rs12995491 0.569 rs6724281 chr2:88529531 T/G cg04511125 chr2:88470314 THNSL2 -0.8 -10.88 -0.51 7.16e-24 Response to metformin (IC50); LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg00815214 chr21:47717953 NA -0.36 -6.11 -0.31 2.77e-9 Testicular germ cell tumor; LIHC cis rs9503598 0.662 rs2326232 chr6:3451953 A/G cg00476032 chr6:3446245 SLC22A23 0.37 7.47 0.37 6.65e-13 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.18 0.32 1.77e-9 Renal cell carcinoma; LIHC cis rs9596863 1.000 rs9568941 chr13:54419426 A/G ch.13.53330881F chr13:54432880 NA 0.44 5.97 0.31 5.84e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs12701220 0.817 rs1058727 chr7:1087095 A/G cg18765753 chr7:1198926 ZFAND2A -0.4 -5.77 -0.3 1.82e-8 Bronchopulmonary dysplasia; LIHC cis rs9309473 1.000 rs7582606 chr2:73813945 A/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.56 -0.33 1.94e-10 Metabolite levels; LIHC cis rs10744422 1.000 rs2135014 chr12:123333065 C/T cg07706471 chr12:123319906 HIP1R -0.62 -8.23 -0.41 4.12e-15 Schizophrenia; LIHC cis rs244293 0.831 rs11654268 chr17:53151290 A/G cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.41 0.37 9.92e-13 Menarche (age at onset); LIHC cis rs990171 0.607 rs871659 chr2:102771855 C/T cg22835712 chr2:102737379 NA 0.51 7.34 0.37 1.61e-12 Lymphocyte counts; LIHC cis rs425277 0.585 rs3107156 chr1:2060630 T/C cg04315214 chr1:2043799 PRKCZ 0.43 6.45 0.33 3.87e-10 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05739825 chr11:125439882 EI24 0.41 6.04 0.31 4.12e-9 Pancreatic cancer; LIHC cis rs4888262 0.545 rs36097721 chr16:74648267 C/G cg01733217 chr16:74700730 RFWD3 0.86 16.84 0.67 9.26e-47 Testicular germ cell tumor; LIHC cis rs67460515 0.563 rs9876142 chr3:160780968 A/G cg03342759 chr3:160939853 NMD3 0.57 7.94 0.39 2.96e-14 Parkinson's disease; LIHC cis rs6066825 0.644 rs761271 chr20:47315637 A/G cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.76e-12 Colorectal cancer; LIHC cis rs8062405 0.755 rs56272201 chr16:28580685 A/G cg16576597 chr16:28551801 NUPR1 0.47 7.15 0.36 5.35e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs72781680 0.851 rs12612830 chr2:24134599 C/T cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs11025559 0.796 rs10833317 chr11:20412277 A/T cg19653624 chr11:20408972 PRMT3 -0.5 -6.39 -0.33 5.34e-10 Pursuit maintenance gain; LIHC cis rs716804 0.703 rs4910115 chr11:10269375 A/T cg01453529 chr11:10209919 SBF2 -0.29 -5.89 -0.3 9.21e-9 Neuroticism; LIHC cis rs1144333 1.000 rs5745327 chr1:76270040 A/T cg10523679 chr1:76189770 ACADM -0.44 -6.5 -0.33 2.76e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs3106136 0.807 rs7657805 chr4:95273659 C/T cg11021082 chr4:95130006 SMARCAD1 0.43 7.46 0.37 7.08e-13 Capecitabine sensitivity; LIHC cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs35883536 1.000 rs1577508 chr1:101089289 T/C cg14515779 chr1:101123966 NA -0.68 -13.21 -0.58 1.81e-32 Monocyte count; LIHC trans rs10411161 0.810 rs77458785 chr19:52384295 T/G cg22319618 chr22:45562946 NUP50 -0.6 -7.09 -0.36 7.95e-12 Breast cancer; LIHC cis rs74417235 0.610 rs35212808 chr5:154057808 A/G cg08893839 chr5:154027129 NA 0.49 6.69 0.34 9.21e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs3008870 1.000 rs2815357 chr1:67491854 T/C cg02640540 chr1:67518911 SLC35D1 0.44 6.08 0.31 3.29e-9 Lymphocyte percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20697630 chr1:20960374 PINK1 0.52 7.36 0.37 1.34e-12 Lung function (FEV1/FVC); LIHC cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg02290350 chr8:58132656 NA 0.41 8.59 0.42 3.16e-16 Developmental language disorder (linguistic errors); LIHC cis rs1707322 0.721 rs6665808 chr1:46162283 C/T cg06784218 chr1:46089804 CCDC17 0.4 7.49 0.38 6.04e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8180040 0.966 rs9683177 chr3:47490493 G/A cg16586182 chr3:47516702 SCAP -0.57 -11.05 -0.51 1.77e-24 Colorectal cancer; LIHC cis rs3862030 0.720 rs7081467 chr10:104231662 G/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -7.26 -0.37 2.68e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs769267 0.930 rs2099334 chr19:19578450 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.95 0.31 6.6e-9 Tonsillectomy; LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg05484376 chr2:27715224 FNDC4 0.39 6.5 0.33 2.78e-10 Menopause (age at onset); LIHC cis rs7552404 0.696 rs1417405 chr1:76457797 T/C cg03433033 chr1:76189801 ACADM 0.59 7.03 0.36 1.13e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs3736485 0.932 rs2278988 chr15:51915234 A/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.15 -0.32 2.22e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1577917 0.740 rs9344533 chr6:86236188 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.66 0.34 1.12e-10 Response to antipsychotic treatment; LIHC cis rs67981189 0.593 rs221918 chr14:71588415 C/G cg15816911 chr14:71606274 NA -0.44 -6.98 -0.35 1.51e-11 Schizophrenia; LIHC cis rs7216064 1.000 rs9897982 chr17:65879592 G/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.59 -0.46 1.85e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs11758351 1.000 rs80095925 chr6:26184942 C/T cg03785755 chr6:26196794 NA 0.53 5.76 0.3 1.89e-8 Gout;Renal underexcretion gout; LIHC cis rs4423214 1.000 rs2852853 chr11:71150217 C/T cg24826892 chr11:71159390 DHCR7 0.51 6.64 0.34 1.22e-10 Vitamin D levels; LIHC cis rs9612 0.718 rs173202 chr19:44253588 C/T cg08581076 chr19:44259116 C19orf61 0.6 7.83 0.39 6.17e-14 Exhaled nitric oxide output; LIHC cis rs9325144 0.600 rs34138871 chr12:38735261 A/G cg26384229 chr12:38710491 ALG10B 0.59 8.28 0.41 2.77e-15 Morning vs. evening chronotype; LIHC cis rs12971120 0.891 rs2303463 chr18:72168608 G/A cg26446133 chr18:72167187 CNDP2 -0.8 -14.74 -0.62 2.02e-38 Refractive error; LIHC cis rs17685 0.753 rs1104878 chr7:75685593 G/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.34 -0.32 7.24e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9733 0.744 rs12568757 chr1:150729793 C/T cg13175981 chr1:150552382 MCL1 0.5 7.33 0.37 1.66e-12 Tonsillectomy; LIHC cis rs4665809 1.000 rs10048683 chr2:26320519 C/T cg27170947 chr2:26402098 FAM59B -0.62 -7.71 -0.38 1.37e-13 Gut microbiome composition (summer); LIHC cis rs60733400 0.818 rs10909839 chr1:2708430 G/A cg18854424 chr1:2615690 NA 0.32 7.04 0.36 1.04e-11 Multiple sclerosis; LIHC cis rs6542838 0.582 rs6542845 chr2:99537600 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -6.89 -0.35 2.63e-11 Fear of minor pain; LIHC cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg08499158 chr17:42289980 UBTF -0.51 -8.96 -0.44 2.15e-17 Total body bone mineral density; LIHC cis rs8103278 1.000 rs36091860 chr19:46312880 G/A cg02376097 chr19:46275166 DMPK -0.44 -6.91 -0.35 2.33e-11 Coronary artery disease; LIHC cis rs7131987 0.675 rs1436322 chr12:29554805 A/G cg14222432 chr12:29376421 FAR2 -0.31 -6.1 -0.31 2.95e-9 QT interval; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18185028 chr3:154042079 DHX36 0.39 6.18 0.32 1.83e-9 Calcium levels; LIHC cis rs6545883 0.931 rs12713437 chr2:61722904 C/T cg14146966 chr2:61757674 XPO1 0.47 8.17 0.4 6.05e-15 Tuberculosis; LIHC cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg05555928 chr11:63887634 MACROD1 0.54 7.21 0.36 3.64e-12 Mean platelet volume; LIHC cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg13047869 chr3:10149882 C3orf24 0.54 6.41 0.33 4.82e-10 Alzheimer's disease; LIHC cis rs11588062 0.628 rs3737744 chr1:46810530 C/T cg15696662 chr1:46669221 C1orf190;POMGNT1 -0.41 -6.56 -0.33 2.04e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs4919087 0.683 rs1687371 chr10:98978183 T/A cg25902810 chr10:99078978 FRAT1 -0.55 -6.32 -0.32 8.02e-10 Monocyte count; LIHC trans rs10213084 1.000 rs13147096 chr4:147495321 A/G cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs6952808 0.630 rs1860832 chr7:2161849 G/A cg21782813 chr7:2030301 MAD1L1 0.37 6.28 0.32 1e-9 Bipolar disorder and schizophrenia; LIHC cis rs829880 1.000 rs829880 chr12:98845331 G/T cg25150519 chr12:98850993 NA 0.62 9.48 0.46 4.43e-19 Colonoscopy-negative controls vs population controls; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05663655 chr7:107532014 DLD 0.43 6.55 0.33 2.16e-10 Cognitive function; LIHC trans rs867371 0.717 rs3858954 chr15:82558034 G/C cg18393722 chr15:85113863 UBE2QP1 -0.44 -7.48 -0.37 6.23e-13 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7208859 0.673 rs1347359 chr17:28914529 T/C cg14067834 chr17:29058358 SUZ12P 0.6 6.32 0.32 7.98e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12744310 1.000 rs12032191 chr1:41769218 A/G cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2839186 0.934 rs17182538 chr21:47705673 C/A cg12016809 chr21:47604291 C21orf56 0.41 6.03 0.31 4.27e-9 Testicular germ cell tumor; LIHC trans rs66887589 0.870 rs10518336 chr4:120522934 G/A cg25214090 chr10:38739885 LOC399744 0.43 7.17 0.36 4.59e-12 Diastolic blood pressure; LIHC cis rs4665809 1.000 rs7588802 chr2:26277789 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.74 -9.21 -0.45 3.35e-18 Gut microbiome composition (summer); LIHC cis rs748404 0.516 rs523156 chr15:43811843 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.4 -6.55 -0.33 2.11e-10 Lung cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03160445 chr3:100120349 LNP1;TOMM70A 0.36 6.06 0.31 3.64e-9 Cognitive function; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.17 -0.32 1.91e-9 Total body bone mineral density; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg16449302 chr5:108744973 PJA2 0.36 6.27 0.32 1.09e-9 Calcium levels; LIHC cis rs6964587 1.000 rs12540055 chr7:91707921 A/G cg17063962 chr7:91808500 NA 0.96 19.09 0.72 7.83e-56 Breast cancer; LIHC cis rs311392 0.967 rs4463399 chr8:55089449 T/C cg20636351 chr8:55087400 NA -0.39 -7.89 -0.39 4.05e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs4819052 0.851 rs35064782 chr21:46674360 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.54 0.38 4.13e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs611744 0.604 rs13248461 chr8:109285833 C/T cg21045802 chr8:109455806 TTC35 0.59 10.47 0.49 1.9e-22 Dupuytren's disease; LIHC cis rs4148883 0.645 rs2851287 chr4:100014548 G/A cg12011299 chr4:100065546 ADH4 0.36 7.23 0.36 3.09e-12 Alcohol dependence; LIHC cis rs2839186 0.967 rs2839191 chr21:47695395 C/G cg00612595 chr21:47717864 NA -0.35 -5.77 -0.3 1.81e-8 Testicular germ cell tumor; LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs10779751 1.000 rs1010447 chr1:11269796 A/G cg08854313 chr1:11322531 MTOR 0.68 9.69 0.46 8.89e-20 Body mass index; LIHC cis rs919433 0.963 rs4850787 chr2:198181750 G/A cg10820045 chr2:198174542 NA -0.57 -9.68 -0.46 9.35e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7937682 1.000 rs2186839 chr11:111534442 T/G cg09085632 chr11:111637200 PPP2R1B -1.06 -13.52 -0.59 1.14e-33 Primary sclerosing cholangitis; LIHC cis rs4722166 0.597 rs2069845 chr7:22770149 G/A cg05472934 chr7:22766657 IL6 0.48 7.82 0.39 6.52e-14 Lung cancer; LIHC cis rs1577917 0.958 rs2197648 chr6:86543887 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.1 -0.4 9.8e-15 Response to antipsychotic treatment; LIHC cis rs6750047 0.546 rs2082255 chr2:38273758 C/A cg07380506 chr2:38303506 CYP1B1 0.6 7.72 0.39 1.28e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg11494091 chr17:61959527 GH2 0.35 5.95 0.31 6.79e-9 Height; LIHC cis rs10949834 0.689 rs2269081 chr7:73519887 T/G cg07137043 chr7:73588983 EIF4H -0.63 -6.48 -0.33 3.17e-10 Verbal memory performance (residualized delayed recall change); LIHC cis rs1775715 0.835 rs12266771 chr10:32231380 G/A cg14930904 chr10:32216787 ARHGAP12 0.37 6.4 0.33 5.1e-10 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg06617136 chr1:145470297 ANKRD34A;POLR3GL 0.35 6.07 0.31 3.31e-9 Metabolic traits; LIHC cis rs11122272 0.668 rs2808616 chr1:231554993 C/G cg06096015 chr1:231504339 EGLN1 -0.47 -8.79 -0.43 7.46e-17 Hemoglobin concentration; LIHC cis rs56235845 0.964 rs11746443 chr5:176798306 G/A cg17509989 chr5:176798049 RGS14 0.83 11.97 0.54 7.86e-28 Hemoglobin concentration;Hematocrit; LIHC trans rs208520 0.731 rs12206488 chr6:66999917 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.68 6.79 0.34 5.03e-11 Exhaled nitric oxide output; LIHC cis rs6502050 0.835 rs6502065 chr17:80095642 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.59e-9 Life satisfaction; LIHC cis rs858239 0.601 rs764534 chr7:23153935 C/T cg18081818 chr7:23246105 NA -0.4 -5.98 -0.31 5.71e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs11605275 1.000 rs77993017 chr11:20031388 C/G cg14835545 chr11:20032148 NAV2 -0.8 -7.39 -0.37 1.14e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9303280 0.901 rs883770 chr17:38063381 C/T cg11212589 chr17:38028394 ZPBP2 0.36 7.32 0.37 1.73e-12 Self-reported allergy; LIHC cis rs6061231 0.701 rs6061505 chr20:60960211 G/A cg03945807 chr20:60948434 NA 0.35 6.09 0.31 3.03e-9 Colorectal cancer; LIHC cis rs10463316 0.894 rs4246024 chr5:150740987 C/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.67 -0.34 1.05e-10 Metabolite levels (Pyroglutamine); LIHC cis rs400736 0.800 rs225095 chr1:8102801 T/C cg25007680 chr1:8021821 PARK7 0.63 9.77 0.47 4.77e-20 Response to antidepressants and depression; LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg18306943 chr3:40428807 ENTPD3 0.41 7.34 0.37 1.58e-12 Renal cell carcinoma; LIHC cis rs7937682 0.924 rs495460 chr11:111504777 G/A cg09085632 chr11:111637200 PPP2R1B -1.03 -12.34 -0.56 3.41e-29 Primary sclerosing cholangitis; LIHC cis rs11122272 0.735 rs2486740 chr1:231517552 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs10420951 0.579 rs75445489 chr19:18571150 G/A cg10790698 chr19:18539756 SSBP4 -0.42 -6.03 -0.31 4.15e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6840360 0.615 rs72728171 chr4:152469372 C/A cg22705602 chr4:152727874 NA -0.32 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.873 rs9295698 chr6:26566099 T/A cg11502198 chr6:26597334 ABT1 0.45 6.51 0.33 2.66e-10 Intelligence (multi-trait analysis); LIHC cis rs921968 0.613 rs1344642 chr2:219555262 G/A cg02985541 chr2:219472218 PLCD4 -0.38 -6.47 -0.33 3.47e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs26949 0.511 rs11740327 chr5:59899413 G/A cg02684056 chr5:59996105 DEPDC1B 0.4 5.99 0.31 5.32e-9 Intelligence (multi-trait analysis); LIHC cis rs7107174 0.792 rs12291726 chr11:78088210 A/G cg02023728 chr11:77925099 USP35 0.45 8.32 0.41 2.08e-15 Testicular germ cell tumor; LIHC cis rs17608059 0.545 rs9915045 chr17:13902636 G/T cg27005118 chr17:13972210 COX10 -0.36 -6.63 -0.34 1.32e-10 Temperament; LIHC cis rs651907 0.557 rs34181125 chr3:101490278 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 11.95 0.54 9.43e-28 Colorectal cancer; LIHC cis rs12464559 0.522 rs4316939 chr2:152525120 C/T cg01189475 chr2:152685088 ARL5A -0.71 -9.2 -0.45 3.49e-18 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs8114671 0.935 rs6058198 chr20:33748253 T/A cg07148914 chr20:33460835 GGT7 0.43 5.94 0.31 6.9e-9 Height; LIHC cis rs208520 0.690 rs4386800 chr6:66755242 A/G cg07460842 chr6:66804631 NA 0.77 8.96 0.44 2.12e-17 Exhaled nitric oxide output; LIHC cis rs17125944 0.556 rs12588482 chr14:53311552 G/A cg00686598 chr14:53173677 PSMC6 -0.86 -9.99 -0.48 8.71e-21 Alzheimer's disease (late onset); LIHC cis rs35110281 0.774 rs2838327 chr21:45018566 A/C cg04455712 chr21:45112962 RRP1B 0.45 7.72 0.39 1.29e-13 Mean corpuscular volume; LIHC cis rs1005277 0.565 rs2474565 chr10:38380828 A/G cg00409905 chr10:38381863 ZNF37A -0.6 -10.3 -0.49 7.81e-22 Extrinsic epigenetic age acceleration; LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg06873352 chr17:61820015 STRADA 0.55 8.62 0.42 2.44e-16 Height; LIHC cis rs611744 0.870 rs634216 chr8:109174803 A/G cg21045802 chr8:109455806 TTC35 0.59 10.04 0.48 5.95e-21 Dupuytren's disease; LIHC cis rs6456156 0.565 rs2181058 chr6:167465330 A/T cg12798992 chr6:167411361 FGFR1OP 0.42 6.61 0.34 1.48e-10 Primary biliary cholangitis; LIHC cis rs1403694 0.966 rs1648715 chr3:186439618 A/G cg12454167 chr3:186435060 KNG1 0.29 7.17 0.36 4.62e-12 Blood protein levels; LIHC cis rs6714710 0.603 rs34502870 chr2:98405929 A/G cg26665480 chr2:98280029 ACTR1B 0.44 6.22 0.32 1.44e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg24209194 chr3:40518798 ZNF619 -0.66 -10.13 -0.48 2.81e-21 Renal cell carcinoma; LIHC cis rs4820539 1.000 rs916585 chr22:23469438 G/A cg21100191 chr22:23484243 RTDR1 0.92 17.13 0.68 6.07e-48 Bone mineral density; LIHC cis rs9868809 0.881 rs3806694 chr3:48672334 G/C cg07636037 chr3:49044803 WDR6 -0.56 -6.45 -0.33 3.85e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22456539 chr1:11741693 MAD2L2 0.42 6.23 0.32 1.39e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2018683 0.899 rs10479817 chr7:28978148 A/C cg19402173 chr7:128379420 CALU -0.39 -6.27 -0.32 1.09e-9 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs8062405 1.000 rs56358680 chr16:28843118 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.21 0.32 1.52e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg24846343 chr22:24311635 DDTL -0.66 -12.48 -0.56 1.02e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1707322 0.964 rs785483 chr1:46559171 T/C cg03146154 chr1:46216737 IPP -0.45 -7.27 -0.37 2.52e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7523273 0.597 rs2761437 chr1:207923081 A/G cg22525895 chr1:207977042 MIR29B2 0.64 7.52 0.38 4.85e-13 Schizophrenia; LIHC trans rs1005277 0.541 rs2263163 chr10:38389887 G/A cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs17286411 0.750 rs4788575 chr16:71931126 T/G cg06353428 chr16:71660113 MARVELD3 0.54 6.82 0.35 4.02e-11 Blood protein levels; LIHC cis rs1904096 0.506 rs8336 chr4:95211610 A/G cg11021082 chr4:95130006 SMARCAD1 -0.46 -8.72 -0.43 1.26e-16 Type 2 diabetes; LIHC cis rs5769765 0.865 rs10854860 chr22:50320029 G/T cg09182678 chr22:50328711 NA -0.39 -5.82 -0.3 1.36e-8 Schizophrenia; LIHC cis rs6449957 0.590 rs6881033 chr5:67529191 A/G cg23036683 chr5:67512108 NA -0.4 -5.8 -0.3 1.5e-8 Cleft lip with or without cleft palate; LIHC cis rs140364877 1 rs140364877 chr7:1885178 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -6.28 -0.32 1.03e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs2404602 0.669 rs12438540 chr15:76943213 C/G cg03037974 chr15:76606532 NA 0.74 14.44 0.62 3.1e-37 Blood metabolite levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14485789 chr2:236586744 AGAP1 0.41 6.05 0.31 3.76e-9 Longevity; LIHC cis rs67311347 0.866 rs11712426 chr3:40330322 G/A cg09455208 chr3:40491958 NA 0.32 6.11 0.31 2.71e-9 Renal cell carcinoma; LIHC cis rs4474465 0.688 rs7927494 chr11:78280578 G/A cg02023728 chr11:77925099 USP35 -0.36 -6.29 -0.32 9.63e-10 Alzheimer's disease (survival time); LIHC cis rs1005277 0.579 rs2474574 chr10:38387295 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs9818758 0.607 rs11710247 chr3:49249800 G/T cg07636037 chr3:49044803 WDR6 -0.8 -8.17 -0.4 6.25e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg19539972 chr4:7069911 GRPEL1 0.65 9.53 0.46 3.02e-19 Monocyte percentage of white cells; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg11494091 chr17:61959527 GH2 0.43 7.85 0.39 5.26e-14 Prudent dietary pattern; LIHC cis rs2404602 0.692 rs10444858 chr15:76962504 T/C cg03037974 chr15:76606532 NA 0.74 14.47 0.62 2.47e-37 Blood metabolite levels; LIHC cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9503598 0.636 rs7775474 chr6:3468224 T/C cg00476032 chr6:3446245 SLC22A23 0.4 7.67 0.38 1.77e-13 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg09417038 chr21:47716443 C21orf57 0.46 7.03 0.36 1.11e-11 Testicular germ cell tumor; LIHC cis rs988712 0.705 rs10501087 chr11:27670108 C/T cg18117895 chr11:27722066 BDNF -0.5 -6.91 -0.35 2.33e-11 Obesity; LIHC cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg09222892 chr1:25734099 RHCE -0.47 -8.72 -0.43 1.26e-16 Plateletcrit;Mean corpuscular volume; LIHC cis rs68170813 0.559 rs11761181 chr7:106954879 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.88 -0.3 9.71e-9 Coronary artery disease; LIHC cis rs7592578 0.599 rs62180992 chr2:191285732 A/G cg27211696 chr2:191398769 TMEM194B -0.51 -6.57 -0.33 1.87e-10 Diastolic blood pressure; LIHC cis rs17685 0.753 rs12531559 chr7:75631697 C/T cg01364799 chr7:75623366 TMEM120A 0.54 8.42 0.41 1.09e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs74417235 0.610 rs35212808 chr5:154057808 A/G cg08754654 chr5:154026448 NA 0.32 7.03 0.36 1.14e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs67311347 0.955 rs1129200 chr3:40532257 T/C cg13409248 chr3:40428643 ENTPD3 0.39 6.17 0.32 1.94e-9 Renal cell carcinoma; LIHC cis rs561341 0.739 rs6505267 chr17:30225950 A/C cg13647721 chr17:30228624 UTP6 0.75 8.32 0.41 2.13e-15 Hip circumference adjusted for BMI; LIHC cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs12477438 0.953 rs3851334 chr2:99794704 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -7.75 -0.39 1.07e-13 Chronic sinus infection; LIHC cis rs6963495 0.745 rs818620 chr7:105172685 G/C cg19920283 chr7:105172520 RINT1 0.77 8.62 0.42 2.6e-16 Bipolar disorder (body mass index interaction); LIHC cis rs7799006 0.657 rs10447540 chr7:2301484 A/G cg02951883 chr7:2050386 MAD1L1 -0.4 -6.08 -0.31 3.13e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2455601 0.882 rs11042116 chr11:8928472 G/C cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -6.17 -0.32 1.91e-9 Schizophrenia; LIHC cis rs611744 0.934 rs609102 chr8:109227406 A/G cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs12540874 0.698 rs10899736 chr7:50546925 C/T cg18232548 chr7:50535776 DDC -0.41 -6.38 -0.33 5.85e-10 Systemic sclerosis; LIHC cis rs13161895 1.000 rs12654148 chr5:179438920 T/A cg06664874 chr5:179499304 RNF130 -0.58 -7.12 -0.36 6.37e-12 LDL cholesterol; LIHC cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.93 8.42 0.41 1.04e-15 Platelet count; LIHC cis rs12908161 0.959 rs12908699 chr15:85240403 G/T cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC cis rs709400 1.000 rs6593 chr14:104163282 G/A cg26031613 chr14:104095156 KLC1 1.03 13.02 0.58 9.24e-32 Body mass index; LIHC cis rs11763147 1 rs11763147 chr7:65326821 C/T cg26939375 chr7:64535504 NA -0.46 -6.97 -0.35 1.6e-11 Corneal structure; LIHC cis rs72634258 0.503 rs34177663 chr1:7833228 A/G cg26816564 chr1:7831052 VAMP3 0.72 6.87 0.35 3.09e-11 Inflammatory bowel disease; LIHC cis rs4927850 0.881 rs7624638 chr3:195748729 C/T cg01181863 chr3:195395398 SDHAP2 -0.53 -6.91 -0.35 2.42e-11 Pancreatic cancer; LIHC cis rs4788570 0.566 rs72791974 chr16:71478574 A/T cg06353428 chr16:71660113 MARVELD3 -1.11 -10.04 -0.48 6.1e-21 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.692 rs35170561 chr15:77130695 C/T cg03037974 chr15:76606532 NA 0.74 14.63 0.62 5.72e-38 Blood metabolite levels; LIHC cis rs74417235 0.639 rs7443642 chr5:154053450 A/G cg08754654 chr5:154026448 NA -0.32 -7.2 -0.36 3.8e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs116248771 0.739 rs114379619 chr3:158338781 C/T cg16708174 chr3:158430962 RARRES1 0.47 6.28 0.32 1.04e-9 diarrhoeal disease at age 2; LIHC cis rs9486719 0.947 rs11153071 chr6:97039741 G/A cg18709589 chr6:96969512 KIAA0776 -0.47 -5.76 -0.3 1.83e-8 Migraine;Coronary artery disease; LIHC cis rs10078 0.571 rs2561664 chr5:459793 T/C cg08916839 chr5:415575 AHRR 0.6 12.6 0.56 3.64e-30 Fat distribution (HIV); LIHC cis rs9560113 0.573 rs1888304 chr13:112242454 A/G cg10483660 chr13:112241077 NA 0.26 6.56 0.33 2e-10 Menarche (age at onset); LIHC cis rs7520050 0.966 rs1707335 chr1:46571921 C/T cg03146154 chr1:46216737 IPP -0.38 -6.25 -0.32 1.22e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs2286885 1.000 rs4837093 chr9:129254443 G/A cg15282417 chr9:129245246 FAM125B 0.39 6.28 0.32 1.01e-9 Intraocular pressure; LIHC cis rs3806843 0.966 rs11741994 chr5:140145949 G/A cg26395211 chr5:140044315 WDR55 -0.41 -6.0 -0.31 4.91e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs3820068 0.581 rs59991988 chr1:15950552 T/A cg17385448 chr1:15911702 AGMAT 0.34 6.03 0.31 4.2e-9 Systolic blood pressure; LIHC cis rs1568889 0.838 rs10767708 chr11:28294847 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.23 0.61 2.02e-36 Bipolar disorder; LIHC trans rs1814175 0.645 rs11040661 chr11:49952146 G/T cg03929089 chr4:120376271 NA -0.84 -15.86 -0.65 7.39e-43 Height; LIHC cis rs4969178 0.620 rs7219625 chr17:76390080 C/T cg02836325 chr17:76403955 PGS1 0.34 6.62 0.34 1.36e-10 HDL cholesterol levels; LIHC cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg02034447 chr16:89574710 SPG7 0.49 7.38 0.37 1.25e-12 Multiple myeloma (IgH translocation); LIHC cis rs17685 0.753 rs1639609 chr7:75683581 T/C cg04610667 chr7:75704037 NA -0.34 -6.1 -0.31 2.91e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7412746 0.658 rs57818453 chr1:150763139 G/A cg17724175 chr1:150552817 MCL1 0.48 9.4 0.45 8.03e-19 Melanoma; LIHC cis rs11671005 0.656 rs11672609 chr19:59006924 C/T cg25952890 chr19:58913133 NA 0.68 6.55 0.33 2.08e-10 Mean platelet volume; LIHC cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.59 -0.56 4.11e-30 Alzheimer's disease; LIHC cis rs4689592 0.503 rs56099074 chr4:7071259 A/G cg26116260 chr4:7069785 GRPEL1 -1.04 -17.61 -0.69 7.19e-50 Monocyte percentage of white cells; LIHC cis rs317689 0.513 rs317678 chr12:69692166 C/G cg20891283 chr12:69753455 YEATS4 0.65 11.14 0.52 8.5e-25 Response to diuretic therapy; LIHC cis rs2354432 1.000 rs2120003 chr1:146690635 A/G cg25205988 chr1:146714368 CHD1L 0.76 8.81 0.43 6.58e-17 Mitochondrial DNA levels; LIHC cis rs3020736 0.500 rs5996110 chr22:42493767 A/G cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs2153535 0.563 rs1737584 chr6:8536742 C/T cg21535247 chr6:8435926 SLC35B3 0.64 8.35 0.41 1.72e-15 Motion sickness; LIHC cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.06 12.24 0.55 8.24e-29 Platelet count; LIHC cis rs599083 0.530 rs2508834 chr11:68175354 C/T cg01657329 chr11:68192670 LRP5 0.58 7.84 0.39 5.89e-14 Bone mineral density (spine); LIHC trans rs10411161 1.000 rs4514789 chr19:52365654 A/G cg22319618 chr22:45562946 NUP50 -0.49 -6.84 -0.35 3.7e-11 Breast cancer; LIHC cis rs9303401 0.615 rs7502342 chr17:56922629 C/A cg25039879 chr17:56429692 SUPT4H1 0.78 8.84 0.43 5.15e-17 Cognitive test performance; LIHC cis rs7727544 0.735 rs273913 chr5:131661156 A/G cg07395648 chr5:131743802 NA -0.29 -6.02 -0.31 4.43e-9 Blood metabolite levels; LIHC cis rs9616064 0.853 rs7284865 chr22:46996529 C/T cg05621596 chr22:47072043 GRAMD4 -0.48 -7.02 -0.35 1.22e-11 Urate levels in obese individuals; LIHC cis rs6546550 0.901 rs897119 chr2:70160658 T/C cg02498382 chr2:70120550 SNRNP27 -0.43 -7.46 -0.37 6.98e-13 Prevalent atrial fibrillation; LIHC trans rs2727020 0.734 rs1164663 chr11:49294723 A/T cg15704280 chr7:45808275 SEPT13 0.76 10.9 0.51 6.19e-24 Coronary artery disease; LIHC cis rs7520050 0.966 rs11211234 chr1:46438787 C/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.43 6.35 0.32 6.93e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7903847 0.642 rs3814553 chr10:99155984 G/A cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.53e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6466055 0.748 rs10266871 chr7:104812129 G/A cg04380332 chr7:105027541 SRPK2 -0.35 -6.56 -0.33 2e-10 Schizophrenia; LIHC cis rs600806 0.850 rs10745354 chr1:109931908 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg07424592 chr7:64974309 NA 0.75 8.73 0.43 1.16e-16 Diabetic kidney disease; LIHC cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg16145915 chr7:1198662 ZFAND2A -0.4 -10.38 -0.49 4.05e-22 Longevity;Endometriosis; LIHC cis rs1986734 0.597 rs4859684 chr4:77419107 C/T cg24201034 chr4:77507246 SHROOM3 -0.38 -6.0 -0.31 5.16e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs4979906 1.000 rs4979906 chr10:79444753 A/G cg07817648 chr10:79422355 NA -0.28 -6.05 -0.31 3.8e-9 Mortality in heart failure; LIHC cis rs10791097 0.694 rs2155750 chr11:130751261 A/C cg14779329 chr11:130786720 SNX19 0.42 6.36 0.33 6.33e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2576037 0.526 rs2571024 chr18:44557877 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.7 -10.99 -0.51 2.84e-24 Personality dimensions; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08595667 chr16:89445453 ANKRD11 0.43 6.05 0.31 3.82e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs919433 0.679 rs61155920 chr2:198528881 C/T cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs367615 0.660 rs10061221 chr5:108839038 C/T cg17395555 chr5:108820864 NA 0.4 8.55 0.42 4.13e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs4246215 1 rs4246215 chr11:61564299 G/T cg27386326 chr11:61587980 NA 0.69 14.85 0.63 7.29e-39 Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid);Platelet count;Inflammatory bowel disease;Trans fatty acid levels;Crohn's disease;Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid);Red blood cell fatty acid levels;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid); LIHC cis rs12701220 0.655 rs34696066 chr7:1140919 C/T cg04025307 chr7:1156635 C7orf50 0.55 7.19 0.36 4.2e-12 Bronchopulmonary dysplasia; LIHC cis rs116248771 0.739 rs10276 chr3:158415166 C/T cg16708174 chr3:158430962 RARRES1 0.49 6.53 0.33 2.43e-10 diarrhoeal disease at age 2; LIHC cis rs2153535 0.580 rs9379222 chr6:8514788 T/C cg23788917 chr6:8435910 SLC35B3 0.62 8.74 0.43 1.08e-16 Motion sickness; LIHC cis rs2386661 0.547 rs57893347 chr10:5646191 G/A cg17085576 chr10:5658249 NA -0.34 -6.18 -0.32 1.83e-9 Breast cancer; LIHC cis rs7617480 0.587 rs9311431 chr3:48848787 T/A cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.28 0.32 1.03e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg14709524 chr16:89940631 TCF25 0.51 6.9 0.35 2.59e-11 Interleukin-17 levels; LIHC cis rs67478160 0.625 rs7141473 chr14:104316055 A/C cg08213375 chr14:104286397 PPP1R13B -0.65 -12.42 -0.56 1.74e-29 Schizophrenia; LIHC cis rs3806843 1.000 rs10477034 chr5:140169730 A/G cg26395211 chr5:140044315 WDR55 -0.43 -6.47 -0.33 3.45e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs9828933 0.832 rs2292662 chr3:63897215 C/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.73 -9.55 -0.46 2.67e-19 Type 2 diabetes; LIHC cis rs16828019 0.852 rs2300649 chr1:41569203 T/C cg20697417 chr1:41786797 NA 0.31 5.91 0.3 8.23e-9 Intelligence (multi-trait analysis); LIHC cis rs4908768 0.906 rs12409937 chr1:8538302 G/C cg25722041 chr1:8623473 RERE 0.41 6.02 0.31 4.5e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6138458 1.000 rs1977540 chr20:24900290 G/T cg26195577 chr20:24973756 C20orf3 -1.09 -13.71 -0.6 2.13e-34 Blood protein levels; LIHC cis rs11971779 0.618 rs10085814 chr7:139064089 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg23758822 chr17:41437982 NA 0.94 17.91 0.7 4.47e-51 Menopause (age at onset); LIHC cis rs9527 0.518 rs11191487 chr10:104734623 A/G cg15744005 chr10:104629667 AS3MT -0.44 -5.98 -0.31 5.6e-9 Arsenic metabolism; LIHC trans rs3812049 0.826 rs6860245 chr5:127367998 G/C cg16011800 chr17:1958478 HIC1 0.51 7.37 0.37 1.26e-12 Lymphocyte counts;Red cell distribution width; LIHC cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg10862848 chr6:42927986 GNMT 0.24 6.0 0.31 5e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7520050 0.966 rs785495 chr1:46587887 A/G cg03146154 chr1:46216737 IPP -0.38 -6.29 -0.32 9.92e-10 Red blood cell count;Reticulocyte count; LIHC cis rs35306767 0.903 rs12264711 chr10:929525 T/C cg20503657 chr10:835505 NA 1.04 11.8 0.54 3.42e-27 Eosinophil percentage of granulocytes; LIHC cis rs589448 0.902 rs315138 chr12:69764850 A/T cg19645103 chr12:69753606 YEATS4 -0.39 -5.87 -0.3 1.02e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs9394841 0.692 rs9349202 chr6:41805581 A/C cg17623882 chr6:41773611 USP49 -0.43 -5.76 -0.3 1.91e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs2573652 1.000 rs12440866 chr15:100517010 G/A cg09918751 chr15:100517450 ADAMTS17 -0.86 -17.03 -0.68 1.55e-47 Height; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs78456975 0.527 rs11884165 chr2:1561052 A/G cg01028140 chr2:1542097 TPO -0.42 -6.6 -0.34 1.61e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2933343 0.621 rs789241 chr3:128585752 G/A cg24203234 chr3:128598194 ACAD9 0.43 5.95 0.31 6.79e-9 IgG glycosylation; LIHC cis rs67478160 0.643 rs2295141 chr14:104212949 T/C cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.57 -0.38 3.54e-13 Schizophrenia; LIHC cis rs116095464 0.558 rs6866776 chr5:264495 C/T cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs13118159 0.801 rs10024996 chr4:1328297 G/A cg16405210 chr4:1374714 KIAA1530 -0.51 -6.43 -0.33 4.24e-10 Longevity; LIHC cis rs6964587 0.869 rs10250014 chr7:91490208 T/C cg17063962 chr7:91808500 NA -0.95 -18.25 -0.7 1.86e-52 Breast cancer; LIHC cis rs2953145 0.617 rs7557192 chr2:241541274 T/C cg07929629 chr2:241523174 NA 0.64 9.17 0.44 4.53e-18 Bipolar disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22246692 chr19:2475189 GADD45B 0.45 6.25 0.32 1.23e-9 Lung function (FEV1/FVC); LIHC cis rs9911578 0.933 rs2531725 chr17:56517962 G/A cg05425664 chr17:57184151 TRIM37 -0.57 -8.41 -0.41 1.14e-15 Intelligence (multi-trait analysis); LIHC cis rs7246657 0.943 rs8106839 chr19:37958475 C/G cg23950597 chr19:37808831 NA -0.47 -6.13 -0.31 2.48e-9 Coronary artery calcification; LIHC cis rs807029 0.577 rs7902510 chr10:102757934 C/T cg25179470 chr10:102756915 LZTS2 0.45 6.23 0.32 1.36e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg06873352 chr17:61820015 STRADA 0.6 9.28 0.45 1.96e-18 Height; LIHC cis rs332507 0.830 rs879535 chr3:124400107 A/G cg05980111 chr3:124395277 KALRN 0.46 7.07 0.36 8.83e-12 Plateletcrit; LIHC cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg09323728 chr8:95962352 TP53INP1 -0.34 -7.49 -0.38 5.95e-13 Type 2 diabetes; LIHC trans rs7618501 0.665 rs7621352 chr3:50070763 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.59 -9.59 -0.46 1.86e-19 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2997447 0.792 rs61775432 chr1:26416376 A/G cg19633962 chr1:26362018 EXTL1 -0.76 -6.75 -0.34 6.25e-11 QRS complex (12-leadsum); LIHC cis rs6430585 0.583 rs58509842 chr2:136586027 G/A cg07169764 chr2:136633963 MCM6 1.33 20.83 0.75 8.23e-63 Corneal structure; LIHC cis rs798554 1.000 rs798545 chr7:2762386 C/T cg13628971 chr7:2884303 GNA12 0.51 7.48 0.37 6.44e-13 Height; LIHC cis rs703842 0.642 rs10876994 chr12:58064737 A/C cg18357645 chr12:58087776 OS9 -0.51 -7.78 -0.39 8.63e-14 Multiple sclerosis; LIHC cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg21724239 chr8:58056113 NA 0.64 7.89 0.39 4.03e-14 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.763 rs7120876 chr11:68261398 C/G cg16797656 chr11:68205561 LRP5 0.52 9.13 0.44 6.32e-18 Total body bone mineral density; LIHC cis rs2180341 0.883 rs6904630 chr6:127696869 A/G cg24812749 chr6:127587940 RNF146 1.06 16.14 0.66 5.7e-44 Breast cancer; LIHC trans rs1005277 0.579 rs2021649 chr10:38392122 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs611744 0.647 rs1448150 chr8:109276161 T/C cg21045802 chr8:109455806 TTC35 0.59 10.35 0.49 5.15e-22 Dupuytren's disease; LIHC cis rs4555082 0.874 rs2816611 chr14:105722976 G/C cg06808227 chr14:105710500 BRF1 -0.62 -8.47 -0.42 7.3e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs12701220 0.655 rs12702117 chr7:1148702 T/C cg09177884 chr7:1199841 ZFAND2A -0.52 -6.06 -0.31 3.69e-9 Bronchopulmonary dysplasia; LIHC cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg14983838 chr19:29218262 NA 0.48 7.51 0.38 5.23e-13 Methadone dose in opioid dependence; LIHC cis rs34540877 1.000 rs117920513 chr19:33147520 C/T cg22980127 chr19:33182716 NUDT19 0.87 6.07 0.31 3.49e-9 Red cell distribution width; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs9790314 0.645 rs10936224 chr3:160902531 G/A cg03342759 chr3:160939853 NMD3 -0.83 -13.65 -0.59 3.62e-34 Morning vs. evening chronotype; LIHC cis rs244731 0.959 rs6556307 chr5:176641434 C/T cg16006841 chr5:176797999 RGS14 0.58 5.76 0.3 1.88e-8 Urate levels in lean individuals; LIHC cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.5 -6.72 -0.34 7.57e-11 Bipolar disorder; LIHC cis rs249954 0.512 rs35634 chr16:23697679 C/T cg09867953 chr16:23706666 ERN2 0.35 5.88 0.3 9.91e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9933309 1.000 rs9933309 chr16:88844932 A/G cg04602696 chr16:88846723 FAM38A -0.5 -9.09 -0.44 8.33e-18 Glycated hemoglobin levels; LIHC cis rs875971 0.862 rs17747530 chr7:65994729 G/C cg11764359 chr7:65958608 NA 0.78 13.62 0.59 4.71e-34 Aortic root size; LIHC cis rs8060686 0.641 rs12446007 chr16:68189054 C/T cg05110241 chr16:68378359 PRMT7 -0.57 -6.31 -0.32 8.81e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs6547741 1.000 rs6750943 chr2:27777904 T/G cg27432699 chr2:27873401 GPN1 0.73 11.78 0.54 4.22e-27 Oral cavity cancer; LIHC cis rs9309473 0.528 rs11126396 chr2:73565143 C/T cg20560298 chr2:73613845 ALMS1 -0.46 -7.33 -0.37 1.67e-12 Metabolite levels; LIHC cis rs9918079 0.542 rs1789 chr4:15664535 G/A cg16509355 chr4:15471240 CC2D2A -0.46 -7.09 -0.36 7.61e-12 Obesity-related traits; LIHC cis rs1443512 0.812 rs1561987 chr12:54335268 C/T cg12374095 chr12:54320830 NA 0.4 5.86 0.3 1.08e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC trans rs61931739 0.534 rs11053049 chr12:34164537 T/C cg26384229 chr12:38710491 ALG10B 0.59 7.5 0.38 5.55e-13 Morning vs. evening chronotype; LIHC cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg04632378 chr13:21900426 NA 0.37 6.13 0.31 2.48e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs875971 0.862 rs6952182 chr7:65683317 T/G cg18252515 chr7:66147081 NA 0.43 6.16 0.32 2.08e-9 Aortic root size; LIHC trans rs1005277 0.579 rs2504140 chr10:38387579 T/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs10493773 1.000 rs55654440 chr1:86176158 G/C cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.45 -0.37 7.71e-13 Urate levels in overweight individuals; LIHC trans rs2727020 0.521 rs7946190 chr11:49521964 T/A cg15704280 chr7:45808275 SEPT13 0.8 11.94 0.54 1.04e-27 Coronary artery disease; LIHC cis rs17685 0.753 rs6951943 chr7:75772452 A/G cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2274273 0.870 rs8023197 chr14:55767395 G/T cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.37e-9 Protein biomarker; LIHC cis rs2115630 0.875 rs8039472 chr15:85361644 A/G cg12501888 chr15:85177176 SCAND2 -0.54 -8.13 -0.4 7.72e-15 P wave terminal force; LIHC trans rs17685 0.712 rs28506984 chr7:75763484 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17539620 0.624 rs7770107 chr6:154836862 A/G cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC cis rs6754311 0.550 rs3213889 chr2:136511575 A/G cg07169764 chr2:136633963 MCM6 -0.69 -9.95 -0.47 1.15e-20 Mosquito bite size; LIHC cis rs67311347 0.911 rs9849224 chr3:40392562 T/C cg24209194 chr3:40518798 ZNF619 0.42 5.97 0.31 6.06e-9 Renal cell carcinoma; LIHC trans rs6446298 1.000 rs6446298 chr3:49860854 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.59 9.52 0.46 3.18e-19 Intelligence (multi-trait analysis); LIHC trans rs12478296 0.581 rs56142391 chr2:242992248 C/T cg01596870 chr19:55963115 NA -0.65 -9.5 -0.46 3.64e-19 Obesity-related traits; LIHC cis rs11626933 1.000 rs2236402 chr14:90734378 C/G cg04374321 chr14:90722782 PSMC1 0.44 6.08 0.31 3.23e-9 Gut microbiota (bacterial taxa); LIHC cis rs919433 0.648 rs3097384 chr2:198278834 T/A cg03934865 chr2:198174659 NA 0.54 8.27 0.41 3.03e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg15691649 chr6:25882328 NA -0.51 -7.38 -0.37 1.22e-12 Blood metabolite levels; LIHC cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg03264133 chr6:25882463 NA -0.87 -12.58 -0.56 4.33e-30 Blood metabolite levels; LIHC cis rs10504073 0.669 rs341802 chr8:50039313 C/T cg00325661 chr8:49890786 NA 0.31 7.04 0.36 1.07e-11 Blood metabolite ratios; LIHC cis rs295140 0.605 rs295149 chr2:201175244 A/G cg23649088 chr2:200775458 C2orf69 -0.43 -6.01 -0.31 4.86e-9 QT interval; LIHC cis rs7927592 0.913 rs11228268 chr11:68287447 A/T cg16797656 chr11:68205561 LRP5 0.52 8.27 0.41 2.96e-15 Total body bone mineral density; LIHC cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.28 0.45 1.98e-18 Bipolar disorder; LIHC cis rs17253792 0.822 rs79291233 chr14:56065302 G/C cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs9649465 1.000 rs7803287 chr7:123354807 T/C cg03229431 chr7:123269106 ASB15 -0.37 -7.96 -0.4 2.58e-14 Migraine; LIHC cis rs2834188 0.924 rs6517160 chr21:34683512 A/G cg14352951 chr21:34696688 IFNAR1 0.46 6.39 0.33 5.51e-10 Narcolepsy; LIHC cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg24879335 chr3:133465180 TF 0.28 6.35 0.32 6.74e-10 Iron status biomarkers; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg11060661 chr22:24314208 DDT;DDTL -0.61 -10.08 -0.48 4.32e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7727544 0.684 rs274560 chr5:131719450 T/C cg07395648 chr5:131743802 NA 0.32 6.56 0.33 1.97e-10 Blood metabolite levels; LIHC cis rs7223966 1.000 rs56383601 chr17:61929968 A/C cg05941027 chr17:61774174 LIMD2 0.37 7.75 0.39 1.07e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7666738 0.830 rs1813972 chr4:98886828 C/A cg05340658 chr4:99064831 C4orf37 0.66 11.92 0.54 1.23e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs68170813 0.559 rs75723759 chr7:106962407 A/G cg02696742 chr7:106810147 HBP1 -0.5 -5.85 -0.3 1.17e-8 Coronary artery disease; LIHC cis rs4148883 0.545 rs17595102 chr4:99986316 C/G cg12011299 chr4:100065546 ADH4 0.33 6.25 0.32 1.21e-9 Alcohol dependence; LIHC cis rs986417 0.748 rs10147346 chr14:61083334 G/C cg27398547 chr14:60952738 C14orf39 0.66 7.26 0.37 2.57e-12 Gut microbiota (bacterial taxa); LIHC cis rs1707322 1.000 rs785517 chr1:46567535 A/T cg03146154 chr1:46216737 IPP -0.46 -7.35 -0.37 1.47e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4853012 0.838 rs58759652 chr2:74344902 A/T cg05890377 chr2:74357713 NA 0.63 12.68 0.57 1.89e-30 Gestational age at birth (maternal effect); LIHC cis rs875971 1.000 rs1167612 chr7:65567976 C/A cg18876405 chr7:65276391 NA -0.43 -7.73 -0.39 1.24e-13 Aortic root size; LIHC cis rs716804 0.819 rs716803 chr11:10247283 C/A cg01453529 chr11:10209919 SBF2 -0.3 -5.92 -0.3 7.89e-9 Neuroticism; LIHC cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg11644478 chr21:40555479 PSMG1 -0.39 -6.06 -0.31 3.52e-9 Cognitive function; LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg06558623 chr16:89946397 TCF25 0.94 14.48 0.62 2.22e-37 Skin colour saturation; LIHC cis rs6952808 0.531 rs4721441 chr7:2184060 A/G cg04267008 chr7:1944627 MAD1L1 -0.47 -7.29 -0.37 2.13e-12 Bipolar disorder and schizophrenia; LIHC cis rs7520050 0.872 rs2486445 chr1:46605369 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.43 6.58 0.34 1.76e-10 Red blood cell count;Reticulocyte count; LIHC cis rs1789 0.868 rs4631041 chr4:15673395 A/T cg24225360 chr4:15471699 CC2D2A -0.38 -5.91 -0.3 8.24e-9 Blood protein levels; LIHC cis rs9611565 0.649 rs4822050 chr22:42177453 C/G cg03806693 chr22:41940476 POLR3H -0.62 -7.39 -0.37 1.15e-12 Vitiligo; LIHC trans rs2243480 1.000 rs1873494 chr7:65649899 T/C cg10756647 chr7:56101905 PSPH -1.07 -13.17 -0.58 2.44e-32 Diabetic kidney disease; LIHC cis rs7512552 0.839 rs1694369 chr1:150351101 A/G cg15654264 chr1:150340011 RPRD2 0.68 11.31 0.52 2.09e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs763121 0.853 rs2284073 chr22:39105948 T/C cg14440974 chr22:39074834 NA -0.36 -6.05 -0.31 3.78e-9 Menopause (age at onset); LIHC cis rs58688157 0.705 rs7941547 chr11:611503 G/A cg16486109 chr11:613632 IRF7 0.61 6.81 0.35 4.44e-11 Systemic lupus erythematosus; LIHC cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg05368731 chr17:41323189 NBR1 0.73 12.53 0.56 6.58e-30 Menopause (age at onset); LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg00106254 chr7:1943704 MAD1L1 -0.42 -6.82 -0.35 4.15e-11 Bipolar disorder and schizophrenia; LIHC cis rs11958404 0.932 rs112683473 chr5:157437819 T/C cg05962755 chr5:157440814 NA 0.99 11.5 0.53 4.32e-26 IgG glycosylation; LIHC cis rs921968 0.643 rs4674320 chr2:219510768 A/G cg18887096 chr2:219472410 PLCD4 0.39 6.74 0.34 6.62e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs5758511 0.634 rs1001587 chr22:42670111 C/T cg20195005 chr22:42527684 CYP2D6 0.31 5.89 0.3 9.43e-9 Birth weight; LIHC cis rs7818688 0.697 rs78777150 chr8:95984411 C/G cg16049864 chr8:95962084 TP53INP1 0.6 6.55 0.33 2.08e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg07061783 chr6:25882402 NA -0.47 -6.48 -0.33 3.29e-10 Blood metabolite levels; LIHC cis rs74544699 1.000 rs57274239 chr4:74789027 A/G cg02530824 chr4:74847766 PF4 0.64 6.68 0.34 9.72e-11 Growth-regulated protein alpha levels; LIHC cis rs6570726 0.935 rs429306 chr6:145827016 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs16828019 0.929 rs11209734 chr1:41698074 C/T cg20697417 chr1:41786797 NA 0.34 6.51 0.33 2.61e-10 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16512924 chr15:28394682 HERC2 0.47 7.35 0.37 1.5e-12 Longevity; LIHC cis rs769267 0.895 rs2916073 chr19:19528324 T/G cg03709012 chr19:19516395 GATAD2A 1.02 18.05 0.7 1.27e-51 Tonsillectomy; LIHC cis rs3823572 0.564 rs2953624 chr7:133659125 C/G cg03336402 chr7:133662267 EXOC4 -0.49 -5.93 -0.31 7.43e-9 Intelligence (multi-trait analysis); LIHC cis rs7674212 0.537 rs2623060 chr4:104047504 G/A cg16532752 chr4:104119610 CENPE -0.46 -7.15 -0.36 5.35e-12 Type 2 diabetes; LIHC cis rs11711311 1.000 rs9855613 chr3:113448455 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.45 -0.37 7.82e-13 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27180563 chr19:13056485 RAD23A -0.41 -6.35 -0.32 6.99e-10 Pancreatic cancer; LIHC cis rs8060686 0.623 rs2418736 chr16:68154862 A/G cg05110241 chr16:68378359 PRMT7 0.48 5.76 0.3 1.91e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs6442522 1.000 rs9847430 chr3:15449640 G/T cg16303742 chr3:15540471 COLQ 0.41 6.95 0.35 1.91e-11 Uric acid levels; LIHC cis rs1403694 0.695 rs11924390 chr3:186433099 T/C cg12454167 chr3:186435060 KNG1 0.4 9.06 0.44 1.01e-17 Blood protein levels; LIHC cis rs1506636 0.646 rs805778 chr7:123214655 C/T cg03229431 chr7:123269106 ASB15 -0.45 -9.07 -0.44 9.84e-18 Plateletcrit;Platelet count; LIHC cis rs4969178 0.965 rs3817294 chr17:76396963 A/G cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs763121 0.886 rs1013339 chr22:38974680 C/T cg21395723 chr22:39101663 GTPBP1 0.39 6.72 0.34 7.71e-11 Menopause (age at onset); LIHC cis rs6831352 0.734 rs2851259 chr4:100033986 C/T cg12011299 chr4:100065546 ADH4 0.56 9.84 0.47 2.69e-20 Alcohol dependence; LIHC cis rs7707921 0.705 rs226194 chr5:81585026 G/T cg15871215 chr5:81402204 ATG10 0.68 8.24 0.41 3.82e-15 Breast cancer; LIHC cis rs763121 0.889 rs2267390 chr22:38889657 C/T cg14440974 chr22:39074834 NA -0.37 -5.84 -0.3 1.2e-8 Menopause (age at onset); LIHC cis rs12477438 0.798 rs10202452 chr2:99569409 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.08 -14.97 -0.63 2.54e-39 Chronic sinus infection; LIHC cis rs713477 0.654 rs12886848 chr14:55911138 G/A cg13175173 chr14:55914753 NA -0.31 -6.74 -0.34 6.64e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs1190552 0.747 rs1190538 chr14:102890919 T/C cg10241871 chr14:102965420 TECPR2 0.41 6.09 0.31 2.96e-9 Blood protein levels; LIHC trans rs4843747 0.708 rs11866437 chr16:88072279 A/G cg26811252 chr16:29126840 RRN3P2 -0.52 -8.24 -0.41 3.72e-15 Menopause (age at onset); LIHC cis rs12188164 0.543 rs2672757 chr5:454732 A/G cg08916839 chr5:415575 AHRR 0.29 6.27 0.32 1.09e-9 Cystic fibrosis severity; LIHC cis rs116095464 0.558 rs7715108 chr5:264661 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs1707322 1.000 rs4606257 chr1:46307268 G/A cg03146154 chr1:46216737 IPP 0.48 7.59 0.38 3.07e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7309 0.935 rs11884495 chr2:162059969 A/T cg21211367 chr2:162094118 NA 0.37 5.73 0.3 2.25e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg09074113 chr2:20870087 GDF7 0.47 10.23 0.48 1.31e-21 Abdominal aortic aneurysm; LIHC cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 7.36 0.37 1.4e-12 Platelet count; LIHC cis rs240764 0.817 rs6938440 chr6:101152009 T/C cg09795085 chr6:101329169 ASCC3 -0.52 -7.25 -0.36 2.82e-12 Neuroticism; LIHC cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg11764359 chr7:65958608 NA 0.69 9.4 0.45 8.19e-19 Calcium levels; LIHC cis rs892961 0.932 rs67415822 chr17:75412678 A/G cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs8038465 0.594 rs55816897 chr15:73869767 G/T cg15420318 chr15:73925796 NPTN 0.49 7.45 0.37 7.58e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs950776 0.518 rs1979907 chr15:78842239 T/C cg06917634 chr15:78832804 PSMA4 -0.89 -13.32 -0.58 6.91e-33 Sudden cardiac arrest; LIHC cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg27286337 chr10:134555280 INPP5A 0.94 13.39 0.59 3.63e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs67478160 0.704 rs12894254 chr14:104290949 G/C cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.41 -0.37 1.03e-12 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12639422 chr2:64069082 UGP2 0.43 6.14 0.32 2.25e-9 Pancreatic cancer; LIHC cis rs1215050 0.791 rs783950 chr4:98878395 C/T cg05340658 chr4:99064831 C4orf37 -0.38 -5.73 -0.3 2.17e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1577917 0.727 rs9351065 chr6:86360428 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.6 -0.56 3.81e-30 Response to antipsychotic treatment; LIHC cis rs67460515 0.528 rs11915989 chr3:160902259 A/G cg17135325 chr3:160939158 NMD3 0.62 9.17 0.44 4.65e-18 Parkinson's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09097040 chr12:68726427 MDM1 -0.42 -6.46 -0.33 3.54e-10 Cognitive function; LIHC cis rs4631830 0.720 rs113082846 chr10:51502802 G/C cg16070123 chr10:51489643 NA -0.38 -5.97 -0.31 6.05e-9 Prostate-specific antigen levels; LIHC cis rs35306767 0.903 rs12250937 chr10:900209 C/T cg20503657 chr10:835505 NA 1.07 12.04 0.55 4.32e-28 Eosinophil percentage of granulocytes; LIHC cis rs12579753 0.913 rs17749243 chr12:82178079 A/C cg07988820 chr12:82153109 PPFIA2 -0.48 -5.9 -0.3 8.92e-9 Resting heart rate; LIHC cis rs3008870 0.755 rs2815349 chr1:67472280 G/A cg02640540 chr1:67518911 SLC35D1 0.44 6.83 0.35 3.83e-11 Lymphocyte percentage of white cells; LIHC trans rs916888 0.779 rs199528 chr17:44843136 C/T cg16836995 chr17:43662488 NA -0.73 -7.2 -0.36 3.74e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7572733 0.534 rs13026569 chr2:198783330 C/G cg10820045 chr2:198174542 NA -0.47 -7.19 -0.36 4.07e-12 Dermatomyositis; LIHC cis rs2032447 0.613 rs6456708 chr6:26032847 G/C cg18357526 chr6:26021779 HIST1H4A 0.61 9.11 0.44 7.09e-18 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.78 0.62 1.38e-38 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs11671005 0.735 rs3826683 chr19:58918733 T/C cg25952890 chr19:58913133 NA 0.69 7.4 0.37 1.07e-12 Mean platelet volume; LIHC trans rs1005277 0.579 rs1740742 chr10:38518860 C/T cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs9926296 0.609 rs4785714 chr16:89798404 G/T cg27121462 chr16:89883253 FANCA -0.37 -5.95 -0.31 6.54e-9 Vitiligo; LIHC cis rs5769765 0.542 rs1535189 chr22:50249131 T/C cg09182678 chr22:50328711 NA 0.46 6.0 0.31 5.01e-9 Schizophrenia; LIHC cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.73 -0.3 2.25e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10193935 1.000 rs13391906 chr2:42538617 C/G cg27598129 chr2:42591480 NA -0.72 -10.75 -0.5 2e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs2274273 0.905 rs10134800 chr14:55635209 A/G cg01864836 chr14:55583639 NA -0.42 -8.19 -0.4 5.21e-15 Protein biomarker; LIHC trans rs11098499 0.697 rs35280960 chr4:120257059 G/A cg25214090 chr10:38739885 LOC399744 0.53 8.3 0.41 2.49e-15 Corneal astigmatism; LIHC cis rs11112613 0.775 rs61200462 chr12:105969271 G/A cg03607813 chr12:105948248 NA 0.62 11.63 0.53 1.45e-26 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs10028773 0.515 rs9994651 chr4:120587803 C/T cg09307838 chr4:120376055 NA 0.49 7.16 0.36 4.87e-12 Educational attainment; LIHC trans rs7618501 0.516 rs2856236 chr3:50161717 A/C cg21659725 chr3:3221576 CRBN -0.64 -10.03 -0.48 6.44e-21 Intelligence (multi-trait analysis); LIHC cis rs546131 0.642 rs508062 chr11:34843820 C/G cg11058730 chr11:34937778 PDHX;APIP 0.65 9.31 0.45 1.64e-18 Lung disease severity in cystic fibrosis; LIHC cis rs769267 0.930 rs9917108 chr19:19572785 A/G cg03709012 chr19:19516395 GATAD2A 1.03 18.52 0.71 1.52e-53 Tonsillectomy; LIHC cis rs12477438 0.501 rs11123770 chr2:99825102 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.58 10.41 0.49 3.27e-22 Chronic sinus infection; LIHC cis rs7647973 0.626 rs9824435 chr3:49674343 A/G cg03060546 chr3:49711283 APEH -0.55 -6.01 -0.31 4.81e-9 Menarche (age at onset); LIHC cis rs7927592 0.956 rs11228269 chr11:68289796 A/G cg01657329 chr11:68192670 LRP5 -0.46 -6.03 -0.31 4.3e-9 Total body bone mineral density; LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg05025164 chr4:1340916 KIAA1530 0.76 11.79 0.54 3.75e-27 Longevity; LIHC cis rs3924048 0.559 rs6541038 chr1:12626210 G/T cg00291366 chr1:12616550 NA 0.36 7.66 0.38 1.95e-13 Optic cup area; LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs72627123 0.656 rs77660260 chr14:74569573 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.86 8.36 0.41 1.65e-15 Morning vs. evening chronotype; LIHC cis rs79057730 0.599 rs112891948 chr7:816059 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.85 9.71 0.46 7.86e-20 Initial pursuit acceleration; LIHC cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.38e-12 Bipolar disorder; LIHC cis rs703842 1.000 rs11172333 chr12:58170335 A/G cg18357645 chr12:58087776 OS9 -0.44 -6.82 -0.35 4.17e-11 Multiple sclerosis; LIHC cis rs1577917 0.958 rs12212480 chr6:86458777 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.25 -0.37 2.79e-12 Response to antipsychotic treatment; LIHC cis rs508618 0.697 rs7534248 chr1:231554531 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.67 9.6 0.46 1.76e-19 Red blood cell count; LIHC cis rs600806 0.893 rs370088 chr1:109858119 T/C cg23091122 chr1:110024289 SYPL2 -0.45 -5.93 -0.31 7.4e-9 Intelligence (multi-trait analysis); LIHC cis rs9649465 0.967 rs1005568 chr7:123306470 G/A cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.56e-14 Migraine; LIHC cis rs365132 1.000 rs2055619 chr5:176415964 A/G cg16309518 chr5:176445507 NA -0.58 -11.56 -0.53 2.58e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg17371911 chr8:10683139 PINX1;MIR1322 -0.47 -6.06 -0.31 3.52e-9 Monocyte count; LIHC cis rs2075371 0.547 rs12666682 chr7:134021784 C/A cg20476274 chr7:133979776 SLC35B4 0.47 6.27 0.32 1.08e-9 Mean platelet volume; LIHC cis rs3796619 1.000 rs28620427 chr4:1086247 T/G cg27284194 chr4:1044797 NA 0.62 10.41 0.49 3.16e-22 Recombination rate (males); LIHC cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg16497277 chr3:49208875 KLHDC8B -0.5 -6.3 -0.32 8.97e-10 Menarche (age at onset); LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.89 -0.3 9.32e-9 Menopause (age at onset); LIHC cis rs9457247 1.000 rs2769354 chr6:167379771 G/T cg23791538 chr6:167370224 RNASET2 0.69 11.76 0.54 4.7e-27 Crohn's disease; LIHC cis rs9534288 0.797 rs4294711 chr13:46575557 C/T cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs11792861 0.926 rs12683988 chr9:111867290 T/C cg05043794 chr9:111880884 C9orf5 -0.31 -7.24 -0.36 3.07e-12 Menarche (age at onset); LIHC cis rs67478160 0.619 rs12878682 chr14:104233627 G/C cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.75 -0.39 1.09e-13 Schizophrenia; LIHC cis rs1336900 0.544 rs10888386 chr1:150611957 A/G cg15448220 chr1:150897856 SETDB1 -0.38 -5.91 -0.3 8.22e-9 Blood protein levels; LIHC cis rs9513627 1.000 rs3928270 chr13:100184268 A/G cg25919922 chr13:100150906 NA 0.78 7.13 0.36 5.91e-12 Obesity-related traits; LIHC cis rs12602486 1.000 rs78867692 chr17:42263873 G/C cg13607699 chr17:42295918 UBTF -0.74 -6.4 -0.33 5.05e-10 Glycated hemoglobin levels; LIHC cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg23172400 chr8:95962367 TP53INP1 -0.38 -7.62 -0.38 2.59e-13 Type 2 diabetes; LIHC cis rs3845702 0.736 rs16867131 chr2:180848651 A/G cg01881094 chr2:180872142 CWC22 -1.12 -9.88 -0.47 2.02e-20 Schizophrenia; LIHC cis rs7666738 0.752 rs35436270 chr4:99088280 G/A cg05340658 chr4:99064831 C4orf37 0.7 10.67 0.5 3.88e-23 Colonoscopy-negative controls vs population controls; LIHC trans rs35110281 0.782 rs4818856 chr21:45043495 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.21e-9 Mean corpuscular volume; LIHC cis rs7582180 0.629 rs4850926 chr2:100954117 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.53 0.42 4.82e-16 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.67e-12 Bipolar disorder; LIHC cis rs425277 1.000 rs262676 chr1:2078482 T/A cg24578937 chr1:2090814 PRKCZ 0.5 8.92 0.43 2.77e-17 Height; LIHC cis rs7937682 0.889 rs7926485 chr11:111536670 G/A cg09085632 chr11:111637200 PPP2R1B -1.04 -13.27 -0.58 1.06e-32 Primary sclerosing cholangitis; LIHC cis rs4665809 1.000 rs2384321 chr2:26290054 A/G cg27170947 chr2:26402098 FAM59B -0.68 -8.34 -0.41 1.88e-15 Gut microbiome composition (summer); LIHC cis rs1552244 0.572 rs6783705 chr3:10164783 A/G cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs7914558 0.901 rs35525740 chr10:104941112 A/T cg15744005 chr10:104629667 AS3MT -0.38 -8.65 -0.42 2.09e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs35110281 0.805 rs8131005 chr21:45041954 T/C cg21573476 chr21:45109991 RRP1B -0.47 -9.16 -0.44 4.95e-18 Mean corpuscular volume; LIHC cis rs3806843 0.966 rs2240693 chr5:140183325 G/C cg19875535 chr5:140030758 IK 0.36 5.82 0.3 1.34e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs807029 0.533 rs3740486 chr10:102750623 T/C cg25179470 chr10:102756915 LZTS2 0.45 6.32 0.32 8.06e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9326248 1.000 rs7946257 chr11:117053165 A/G cg26566898 chr11:117069891 TAGLN 0.48 7.66 0.38 1.95e-13 Blood protein levels; LIHC cis rs11190604 1.000 rs7090431 chr10:102261753 A/G cg07080220 chr10:102295463 HIF1AN 0.55 8.01 0.4 1.88e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs897984 0.568 rs4889653 chr16:30895713 C/T cg02466173 chr16:30829666 NA 0.43 6.3 0.32 9.04e-10 Dementia with Lewy bodies; LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs34540877 1.000 rs35017666 chr19:33161314 G/A cg22980127 chr19:33182716 NUDT19 0.86 5.98 0.31 5.74e-9 Red cell distribution width; LIHC cis rs1577917 0.917 rs2197651 chr6:86495442 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.12 -0.36 6.3e-12 Response to antipsychotic treatment; LIHC cis rs7258465 0.931 rs8107351 chr19:18612758 G/A cg10790698 chr19:18539756 SSBP4 -0.35 -7.35 -0.37 1.46e-12 Breast cancer; LIHC cis rs4746818 0.793 rs2805914 chr10:70859291 A/G cg11621586 chr10:70884670 VPS26A 0.73 10.21 0.48 1.49e-21 Left atrial antero-posterior diameter; LIHC cis rs7552404 0.696 rs12140121 chr1:76455001 A/G cg03433033 chr1:76189801 ACADM 0.58 6.88 0.35 2.9100000000000002e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs801193 0.591 rs9986881 chr7:66173040 A/G cg14393609 chr7:65229607 NA 0.39 6.47 0.33 3.37e-10 Aortic root size; LIHC cis rs4746818 1.000 rs4746818 chr10:70884687 G/T cg11621586 chr10:70884670 VPS26A 0.9 15.02 0.63 1.55e-39 Left atrial antero-posterior diameter; LIHC cis rs763121 0.752 rs5757222 chr22:39060473 C/T cg14440974 chr22:39074834 NA -0.43 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC cis rs7020830 0.861 rs6476622 chr9:37308049 T/A cg14294708 chr9:37120828 ZCCHC7 1.04 21.14 0.75 4.79e-64 Schizophrenia; LIHC cis rs344364 0.511 rs911392 chr16:1947259 A/G cg00046913 chr16:1877150 HAGH;FAHD1 -0.48 -5.8 -0.3 1.51e-8 Glomerular filtration rate in chronic kidney disease; LIHC trans rs10242455 0.557 rs73403272 chr7:99134208 T/G cg09045935 chr12:6379348 NA 0.84 7.17 0.36 4.54e-12 Blood metabolite levels; LIHC cis rs8014204 0.868 rs2230237 chr14:75359670 G/A cg08847533 chr14:75593920 NEK9 -0.39 -6.54 -0.33 2.28e-10 Caffeine consumption; LIHC cis rs55665837 0.540 rs12788030 chr11:14764684 C/T cg25251204 chr11:14927456 NA 0.4 5.74 0.3 2.11e-8 Vitamin D levels; LIHC cis rs12477438 0.798 rs972768 chr2:99682397 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.67 -0.53 1.03e-26 Chronic sinus infection; LIHC cis rs826838 1.000 rs860400 chr12:39081279 A/G cg13010199 chr12:38710504 ALG10B -0.41 -5.97 -0.31 5.82e-9 Heart rate; LIHC cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg09904177 chr6:26538194 HMGN4 0.56 10.86 0.51 8.42e-24 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs4238376 chr15:45541887 T/C cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg18357526 chr6:26021779 HIST1H4A 1.01 14.44 0.62 3.14e-37 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.512 rs2425072 chr20:34293686 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.58 -8.21 -0.41 4.47e-15 Total cholesterol levels; LIHC cis rs9534288 0.797 rs7328081 chr13:46611695 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs4555082 0.834 rs2816651 chr14:105708470 A/G cg13114125 chr14:105738426 BRF1 -0.7 -9.43 -0.45 6.54e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs3767633 0.800 rs6685369 chr1:161754834 T/C cg09175582 chr1:161736000 ATF6 0.57 5.88 0.3 9.8e-9 IgG glycosylation; LIHC cis rs703842 1.000 rs10877014 chr12:58167661 A/G cg18357645 chr12:58087776 OS9 -0.44 -6.89 -0.35 2.69e-11 Multiple sclerosis; LIHC cis rs9486719 0.895 rs3798294 chr6:97049587 G/A cg06623918 chr6:96969491 KIAA0776 -0.68 -6.85 -0.35 3.49e-11 Migraine;Coronary artery disease; LIHC cis rs12824058 0.831 rs12310049 chr12:130811260 C/G cg24838063 chr12:130822603 PIWIL1 0.67 9.96 0.47 1.1e-20 Menopause (age at onset); LIHC cis rs1865760 0.532 rs2794719 chr6:26088890 T/G cg18357526 chr6:26021779 HIST1H4A 0.44 6.43 0.33 4.17e-10 Height; LIHC cis rs2073300 1.000 rs6036418 chr20:23449698 A/G cg12062639 chr20:23401060 NAPB 0.61 7.34 0.37 1.6e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9921222 0.500 rs8046256 chr16:393948 C/T cg12437481 chr16:420112 MRPL28 -0.79 -10.75 -0.5 2.11e-23 Bone mineral density (spine);Bone mineral density; LIHC cis rs7432375 0.901 rs7616204 chr3:136444589 C/T cg21827317 chr3:136751795 NA -0.44 -5.83 -0.3 1.27e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs780096 0.546 rs8179225 chr2:27737181 A/G cg05484376 chr2:27715224 FNDC4 0.4 6.61 0.34 1.52e-10 Total body bone mineral density; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg12419862 chr22:24373484 LOC391322 -0.71 -10.71 -0.5 2.83e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10791097 0.967 rs10750450 chr11:130719061 G/T cg12179176 chr11:130786555 SNX19 0.61 9.52 0.46 3.33e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs72634258 0.503 rs72632055 chr1:7835774 T/G cg00864860 chr1:7907996 UTS2 0.6 5.93 0.31 7.29e-9 Inflammatory bowel disease; LIHC cis rs61677309 0.638 rs58162302 chr11:118146199 A/T cg06090739 chr11:118230722 UBE4A 0.32 6.04 0.31 3.98e-9 Lung cancer in ever smokers; LIHC cis rs1448094 0.512 rs7133591 chr12:86239752 G/C cg02569458 chr12:86230093 RASSF9 0.48 6.38 0.33 5.82e-10 Major depressive disorder; LIHC cis rs6545883 0.894 rs6545845 chr2:61437044 G/C cg14146966 chr2:61757674 XPO1 -0.43 -7.25 -0.36 2.8e-12 Tuberculosis; LIHC cis rs7412746 0.611 rs10888395 chr1:150762171 C/T cg17724175 chr1:150552817 MCL1 0.46 9.13 0.44 6.32e-18 Melanoma; LIHC cis rs8180040 1.000 rs295458 chr3:47385585 C/A cg16586182 chr3:47516702 SCAP -0.54 -9.89 -0.47 1.96e-20 Colorectal cancer; LIHC cis rs7520050 0.966 rs7522601 chr1:46419021 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.42 6.24 0.32 1.3e-9 Red blood cell count;Reticulocyte count; LIHC cis rs28735056 1.000 rs59183289 chr18:77631198 A/G cg20368463 chr18:77673604 PQLC1 -0.36 -6.32 -0.32 8.1e-10 Schizophrenia; LIHC cis rs367615 0.704 rs17161885 chr5:108852642 A/G cg17395555 chr5:108820864 NA 0.39 8.34 0.41 1.85e-15 Colorectal cancer (SNP x SNP interaction); LIHC cis rs2280018 1.000 rs2280017 chr16:15151361 A/G cg27102117 chr16:15229624 NA -0.28 -6.04 -0.31 3.93e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg10096929 chr1:156261403 TMEM79 0.41 6.77 0.34 5.47e-11 Tonsillectomy; LIHC cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 11.33 0.52 1.75e-25 Platelet count; LIHC cis rs36051895 0.632 rs7849717 chr9:5170080 G/A cg02405213 chr9:5042618 JAK2 -0.69 -10.5 -0.49 1.54e-22 Pediatric autoimmune diseases; LIHC cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg06618935 chr21:46677482 NA -0.29 -5.73 -0.3 2.21e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs919433 0.713 rs6719729 chr2:198480072 G/A cg10820045 chr2:198174542 NA 0.49 7.76 0.39 1.02e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3731896 1.000 rs3731896 chr2:220146402 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.59 7.08 0.36 8.04e-12 Educational attainment; LIHC cis rs16828019 0.929 rs10524 chr1:41726473 T/C cg20697417 chr1:41786797 NA 0.34 6.53 0.33 2.31e-10 Intelligence (multi-trait analysis); LIHC cis rs2092850 1 rs2092850 chr6:88100419 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.38 -5.82 -0.3 1.36e-8 Itch intensity from mosquito bite; LIHC cis rs7487075 0.558 rs7959095 chr12:46633328 G/T cg15584813 chr12:47219626 SLC38A4 0.32 5.83 0.3 1.26e-8 Itch intensity from mosquito bite; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg10150615 chr22:24372951 LOC391322 -0.45 -6.24 -0.32 1.26e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12477438 1.000 rs12477438 chr2:99841085 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.03 -12.18 -0.55 1.37e-28 Chronic sinus infection; LIHC cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg27572855 chr1:25598939 RHD 0.38 8.17 0.4 5.92e-15 Erythrocyte sedimentation rate; LIHC cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.57 9.75 0.47 5.77e-20 Bipolar disorder; LIHC trans rs2243480 1.000 rs313799 chr7:65494330 A/G cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs736408 0.648 rs3774354 chr3:52817675 G/A cg18404041 chr3:52824283 ITIH1 -0.66 -10.95 -0.51 4.08e-24 Bipolar disorder; LIHC cis rs1163251 0.837 rs517533 chr1:120229170 T/G cg19096424 chr1:120255104 PHGDH 0.64 8.18 0.4 5.57e-15 Blood metabolite levels; LIHC cis rs6121246 0.909 rs6060793 chr20:30288830 T/G cg13852791 chr20:30311386 BCL2L1 0.93 9.54 0.46 2.9e-19 Mean corpuscular hemoglobin; LIHC cis rs7224737 1.000 rs35184688 chr17:40272406 G/C cg00647820 chr17:40259828 DHX58 -0.29 -5.82 -0.3 1.39e-8 Fibrinogen levels; LIHC cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg18404041 chr3:52824283 ITIH1 -0.49 -7.85 -0.39 5.29e-14 Electroencephalogram traits; LIHC cis rs1865721 0.804 rs7229401 chr18:73148127 T/G cg26385618 chr18:73139727 C18orf62 -0.3 -7.85 -0.39 5.35e-14 Intelligence; LIHC cis rs12286929 0.644 rs12099024 chr11:115082142 A/G cg04055981 chr11:115044050 NA 0.46 6.76 0.34 6.05e-11 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05030077 chr16:2255199 MLST8 0.47 6.54 0.33 2.31e-10 Lung function (FEV1/FVC); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08882882 chr6:84937375 KIAA1009 0.42 6.35 0.32 6.81e-10 Cognitive function; LIHC cis rs116095464 0.558 rs10057626 chr5:239720 T/G cg22496380 chr5:211416 CCDC127 -1.02 -10.56 -0.5 9.22e-23 Breast cancer; LIHC cis rs2404602 0.716 rs7164060 chr15:76707694 T/C cg03037974 chr15:76606532 NA 0.8 16.57 0.67 1.05e-45 Blood metabolite levels; LIHC cis rs9399135 0.935 rs4445070 chr6:135309212 C/T cg22676075 chr6:135203613 NA 0.38 6.23 0.32 1.4e-9 Red blood cell count; LIHC cis rs523522 0.962 rs3759394 chr12:120933173 C/A cg12219531 chr12:120966889 COQ5 0.67 13.22 0.58 1.57e-32 High light scatter reticulocyte count; LIHC cis rs72781680 0.821 rs72796378 chr2:24167385 G/A cg08917208 chr2:24149416 ATAD2B 0.65 6.57 0.33 1.86e-10 Lymphocyte counts; LIHC cis rs72781680 1.000 rs6751655 chr2:24155478 A/G cg08917208 chr2:24149416 ATAD2B 0.89 7.89 0.39 4.06e-14 Lymphocyte counts; LIHC cis rs7487075 0.619 rs4768717 chr12:46831561 C/T cg23829395 chr12:46796953 NA 0.34 6.05 0.31 3.81e-9 Itch intensity from mosquito bite; LIHC cis rs589448 0.967 rs2617835 chr12:69753420 C/A cg20891283 chr12:69753455 YEATS4 0.95 22.44 0.77 3.39e-69 Cerebrospinal fluid biomarker levels; LIHC trans rs1432089 0.773 rs62344305 chr4:171787203 C/T cg02328223 chr3:127541927 MGLL -0.42 -6.09 -0.31 3.02e-9 Endometriosis; LIHC cis rs11792861 0.926 rs72607171 chr9:111837776 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.67 0.42 1.82e-16 Menarche (age at onset); LIHC cis rs6598955 0.670 rs7522905 chr1:26609259 C/T cg04990556 chr1:26633338 UBXN11 -0.61 -9.99 -0.48 8.48e-21 Obesity-related traits; LIHC cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg25894440 chr7:65020034 NA -0.58 -6.27 -0.32 1.08e-9 Diabetic kidney disease; LIHC cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.32 0.41 2.15e-15 Platelet count; LIHC cis rs4243830 0.850 rs4908911 chr1:6599523 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.84 -9.45 -0.46 5.47e-19 Body mass index; LIHC cis rs11585357 0.895 rs72633814 chr1:17626456 T/C cg08277548 chr1:17600880 PADI3 -0.65 -6.85 -0.35 3.5e-11 Hair shape; LIHC cis rs1775715 0.870 rs1419168 chr10:32257332 A/C cg14930904 chr10:32216787 ARHGAP12 0.4 7.1 0.36 7.47e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs2236918 0.710 rs1635507 chr1:242028358 G/T cg17736920 chr1:242011382 EXO1 0.6 9.04 0.44 1.16e-17 Menopause (age at onset); LIHC cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg12373951 chr3:133503437 NA 0.43 7.09 0.36 7.95e-12 Iron status biomarkers; LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg09177884 chr7:1199841 ZFAND2A -0.45 -6.52 -0.33 2.58e-10 Longevity;Endometriosis; LIHC cis rs16922576 0.640 rs12343727 chr9:5215926 A/G cg02405213 chr9:5042618 JAK2 -0.59 -9.4 -0.45 7.97e-19 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7216064 1.000 rs11079706 chr17:65835470 G/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.34 -0.45 1.31e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs12980942 0.872 rs10421990 chr19:41797099 C/T cg25627403 chr19:41769009 HNRNPUL1 0.49 6.18 0.32 1.83e-9 Coronary artery disease; LIHC cis rs941873 0.772 rs1892498 chr10:81103862 A/G cg09469691 chr10:81107165 PPIF 0.69 10.52 0.49 1.28e-22 Height; LIHC cis rs7666738 0.579 rs7672718 chr4:98645122 A/G cg05340658 chr4:99064831 C4orf37 0.5 6.48 0.33 3.16e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs11577318 0.853 rs4333841 chr1:26631927 T/C cg10402321 chr1:26617780 UBXN11 -0.38 -5.78 -0.3 1.65e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.55 -0.46 2.52e-19 Initial pursuit acceleration; LIHC cis rs3936840 1.000 rs3936840 chr14:102984274 G/C cg10241871 chr14:102965420 TECPR2 -0.43 -6.69 -0.34 9.13e-11 Plateletcrit; LIHC cis rs7927592 0.956 rs60212556 chr11:68305494 C/T cg20283391 chr11:68216788 NA -0.51 -7.64 -0.38 2.27e-13 Total body bone mineral density; LIHC cis rs1401454 0.967 rs11023881 chr11:16246700 T/A cg02656851 chr11:16430247 SOX6 -0.32 -6.11 -0.31 2.66e-9 Blood pressure; LIHC cis rs7771547 0.507 rs6457918 chr6:36414308 A/T cg07856975 chr6:36356162 ETV7 -0.35 -5.78 -0.3 1.69e-8 Platelet distribution width; LIHC cis rs10751667 0.621 rs7396107 chr11:970029 C/T cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs10463316 0.817 rs1318783 chr5:150814807 T/G cg03212797 chr5:150827313 SLC36A1 -0.46 -6.82 -0.35 4.02e-11 Metabolite levels (Pyroglutamine); LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.67 0.38 1.75e-13 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.843 rs9784070 chr2:172785007 C/T cg13550731 chr2:172543902 DYNC1I2 -0.81 -14.37 -0.61 5.58e-37 Schizophrenia; LIHC cis rs425277 1.000 rs196128 chr1:2078444 T/G cg24578937 chr1:2090814 PRKCZ 0.5 8.92 0.43 2.77e-17 Height; LIHC cis rs7264396 0.563 rs6058296 chr20:34269225 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.51 -6.32 -0.32 8.19e-10 Total cholesterol levels; LIHC cis rs8067545 0.750 rs7208025 chr17:19997870 T/C cg13482628 chr17:19912719 NA 0.49 8.18 0.4 5.6e-15 Schizophrenia; LIHC cis rs546131 0.928 rs546521 chr11:34824773 G/C cg06937548 chr11:34938143 PDHX;APIP 0.53 7.14 0.36 5.62e-12 Lung disease severity in cystic fibrosis; LIHC cis rs10832963 1.000 rs10832962 chr11:18656271 C/T cg09201001 chr11:18656081 SPTY2D1 0.93 17.09 0.68 9.35e-48 Breast cancer; LIHC cis rs801193 0.527 rs2707837 chr7:66181073 G/C cg18252515 chr7:66147081 NA -0.47 -6.86 -0.35 3.24e-11 Aortic root size; LIHC trans rs79976124 0.837 rs10944858 chr6:66646039 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.77 0.34 5.54e-11 Type 2 diabetes; LIHC cis rs7909074 1.000 rs10736831 chr10:45402311 G/A cg05187965 chr10:45406764 TMEM72 -0.27 -6.68 -0.34 9.98e-11 Mean corpuscular volume; LIHC cis rs2239547 0.657 rs6445539 chr3:52874296 G/A cg18404041 chr3:52824283 ITIH1 -0.42 -5.88 -0.3 9.64e-9 Schizophrenia; LIHC cis rs780094 0.544 rs2303370 chr2:27651375 C/T cg21248554 chr2:27665150 KRTCAP3 -0.42 -5.76 -0.3 1.87e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs7131987 0.903 rs7308125 chr12:29425211 T/C cg21522988 chr12:29376872 FAR2 0.27 6.17 0.32 1.98e-9 QT interval; LIHC cis rs473651 0.740 rs502349 chr2:239318389 C/T cg18131467 chr2:239335373 ASB1 1.03 18.4 0.71 4.71e-53 Multiple system atrophy; LIHC cis rs7044106 0.537 rs4434680 chr9:123489688 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.27 0.37 2.41e-12 Hip circumference adjusted for BMI; LIHC cis rs397020 0.904 rs203547 chr20:1195245 T/A cg03932398 chr20:1206703 RAD21L1 0.44 7.22 0.36 3.45e-12 Multiple sclerosis; LIHC cis rs10197940 0.624 rs10497081 chr2:152353395 T/G cg19508488 chr2:152266495 RIF1 0.55 7.77 0.39 9.38e-14 Lung cancer; LIHC cis rs3762637 0.941 rs77599736 chr3:122179509 A/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs35110281 0.565 rs7278003 chr21:44966069 T/C cg01579765 chr21:45077557 HSF2BP -0.32 -6.02 -0.31 4.53e-9 Mean corpuscular volume; LIHC cis rs9381040 0.655 rs2268190 chr6:41030226 C/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.09 -0.31 3.08e-9 Alzheimer's disease (late onset); LIHC cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.25e-12 Bipolar disorder; LIHC cis rs2842992 0.724 rs9347340 chr6:160188891 C/T cg16489826 chr6:160211363 TCP1;MRPL18 -0.57 -10.48 -0.49 1.82e-22 Age-related macular degeneration (geographic atrophy); LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg03721293 chr16:90014378 DEF8 0.41 6.89 0.35 2.62e-11 Skin colour saturation; LIHC cis rs9733 0.818 rs12403609 chr1:150676485 T/C cg18016565 chr1:150552671 MCL1 -0.5 -10.31 -0.49 6.9e-22 Tonsillectomy; LIHC cis rs763121 0.719 rs138699 chr22:39129708 G/A cg14440974 chr22:39074834 NA -0.39 -6.24 -0.32 1.28e-9 Menopause (age at onset); LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.43 0.56 1.58e-29 Prudent dietary pattern; LIHC cis rs919433 0.684 rs55775495 chr2:198245965 C/T cg03934865 chr2:198174659 NA 0.54 8.37 0.41 1.51e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.89 0.3 9.32e-9 Menopause (age at onset); LIHC cis rs6545883 0.929 rs3732171 chr2:61749690 C/T cg14146966 chr2:61757674 XPO1 0.48 8.46 0.42 7.73e-16 Tuberculosis; LIHC cis rs7089973 0.604 rs55759483 chr10:116573423 T/C cg03647239 chr10:116582469 FAM160B1 0.44 6.32 0.32 8.22e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7258015 1.000 rs3176767 chr19:10449751 A/C cg13981319 chr19:10446556 ICAM3 0.39 6.34 0.32 7.06e-10 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs7635838 0.718 rs2594981 chr3:11380638 C/G cg00170343 chr3:11313890 ATG7 0.6 10.02 0.48 6.61e-21 HDL cholesterol; LIHC cis rs929354 0.772 rs1182442 chr7:157026633 G/A cg16102536 chr7:156981717 UBE3C -0.35 -5.9 -0.3 8.69e-9 Body mass index; LIHC cis rs2963155 0.518 rs853176 chr5:142636456 A/G cg17617527 chr5:142782415 NR3C1 -0.89 -10.22 -0.48 1.44e-21 Breast cancer; LIHC cis rs3859192 0.557 rs12602514 chr17:38159745 A/G cg17467752 chr17:38218738 THRA -0.5 -8.62 -0.42 2.53e-16 White blood cell count; LIHC cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg02931644 chr1:25747376 RHCE 0.34 7.29 0.37 2.21e-12 Erythrocyte sedimentation rate; LIHC cis rs7772486 0.846 rs7755440 chr6:146375906 T/C cg23711669 chr6:146136114 FBXO30 0.66 11.66 0.53 1.15e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs9406163 chr6:8466642 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs10883723 0.810 rs61873733 chr10:104251458 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.09 0.58 5.25e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7772486 0.720 rs4896844 chr6:146075224 T/C cg05347473 chr6:146136440 FBXO30 -0.37 -6.0 -0.31 4.96e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4975616 0.869 rs455433 chr5:1336243 A/G cg07493874 chr5:1342172 CLPTM1L -0.68 -11.03 -0.51 2.15e-24 Lung cancer; LIHC cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.15 -16.72 -0.67 2.81e-46 Gut microbiome composition (summer); LIHC cis rs7100689 0.622 rs7897994 chr10:82133304 T/G cg01528321 chr10:82214614 TSPAN14 0.78 10.38 0.49 4e-22 Post bronchodilator FEV1; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01704976 chr3:52273381 TWF2 -0.42 -6.55 -0.33 2.16e-10 Cognitive function; LIHC cis rs17095355 0.786 rs58096078 chr10:111734286 C/G cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.85 -0.3 1.18e-8 Biliary atresia; LIHC cis rs896854 0.548 rs574183 chr8:95973816 A/G cg23172400 chr8:95962367 TP53INP1 0.37 7.02 0.35 1.19e-11 Type 2 diabetes; LIHC cis rs8062405 0.789 rs1968751 chr16:28631759 T/C cg07451762 chr16:28383216 NA -0.38 -6.43 -0.33 4.24e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs916888 0.773 rs169201 chr17:44790203 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.74 6.97 0.35 1.65e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14968603 chr10:102046143 BLOC1S2 -0.39 -6.06 -0.31 3.67e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs79389047 1.000 rs76212864 chr4:157669091 A/T cg18148021 chr14:56616059 PELI2 0.42 6.28 0.32 1.04e-9 Plateletcrit; LIHC cis rs6951245 1.000 rs79443843 chr7:1075245 G/A cg08132940 chr7:1081526 C7orf50 -0.79 -6.69 -0.34 9.08e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3764618 1.000 rs2303049 chr19:49494812 C/T cg14640682 chr19:49496473 GYS1;RUVBL2 -0.73 -5.95 -0.31 6.8e-9 Follicule stimulating hormone; LIHC cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.65 0.38 2e-13 Bipolar disorder; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg00280220 chr17:61926910 NA 0.42 6.73 0.34 7.18e-11 Prudent dietary pattern; LIHC cis rs6667605 0.527 rs12046118 chr1:2540343 A/C cg18854424 chr1:2615690 NA 0.33 7.42 0.37 9.44e-13 Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs317689 0.658 rs490872 chr12:69645864 A/G cg20891283 chr12:69753455 YEATS4 0.48 6.98 0.35 1.55e-11 Response to diuretic therapy; LIHC cis rs10751667 0.600 rs6597948 chr11:1005308 C/T cg20946044 chr11:1010712 AP2A2 -0.34 -5.97 -0.31 6.11e-9 Alzheimer's disease (late onset); LIHC cis rs10911363 0.592 rs2702177 chr1:183450622 G/C cg09173681 chr1:183549694 NCF2 0.54 9.51 0.46 3.46e-19 Systemic lupus erythematosus; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10102242 chr16:4422216 VASN;CORO7 -0.48 -6.71 -0.34 8.06e-11 Pancreatic cancer; LIHC cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg18654377 chr3:49208889 KLHDC8B -0.5 -5.9 -0.3 8.98e-9 Menarche (age at onset); LIHC cis rs7635838 0.750 rs7625680 chr3:11378069 G/A cg00170343 chr3:11313890 ATG7 0.6 10.03 0.48 6.14e-21 HDL cholesterol; LIHC cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg10802521 chr3:52805072 NEK4 -0.43 -7.23 -0.36 3.09e-12 Bipolar disorder; LIHC cis rs4478037 0.822 rs9875140 chr3:33117068 T/A cg27203090 chr3:33138513 GLB1;TMPPE -0.58 -7.42 -0.37 9.39e-13 Major depressive disorder; LIHC cis rs908922 0.676 rs2181172 chr1:152491794 A/G cg20991723 chr1:152506922 NA 0.59 10.48 0.49 1.85e-22 Hair morphology; LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg04025307 chr7:1156635 C7orf50 0.59 10.33 0.49 6.08e-22 Longevity;Endometriosis; LIHC trans rs916888 0.738 rs199515 chr17:44856641 C/G cg16836995 chr17:43662488 NA 0.61 6.46 0.33 3.53e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs12922040 1.000 rs2075516 chr16:15869525 C/T cg27174420 chr16:15820903 MYH11 0.36 6.13 0.31 2.48e-9 Serum uric acid levels in response to allopurinol in gout; LIHC cis rs2832191 0.626 rs2254796 chr21:30341891 A/G cg24692254 chr21:30365293 RNF160 -0.81 -13.72 -0.6 2.01e-34 Dental caries; LIHC trans rs911555 0.723 rs11160751 chr14:103925740 T/C cg17675199 chr6:35436792 RPL10A 0.41 8.42 0.41 1.06e-15 Intelligence (multi-trait analysis); LIHC cis rs6504622 0.537 rs197918 chr17:45003080 A/G cg16759221 chr17:45003025 GOSR2 -0.33 -5.74 -0.3 2.07e-8 Orofacial clefts; LIHC cis rs1461503 0.966 rs4936764 chr11:122844492 G/A cg14473756 chr11:122847823 NA -0.37 -6.79 -0.34 4.99e-11 Menarche (age at onset); LIHC cis rs4713118 0.955 rs9468204 chr6:27688809 C/T cg20933634 chr6:27740509 NA 0.46 6.2 0.32 1.64e-9 Parkinson's disease; LIHC cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg15691649 chr6:25882328 NA -0.39 -6.22 -0.32 1.44e-9 Height; LIHC cis rs7715806 0.500 rs77544433 chr5:75001025 C/A cg00601450 chr5:74908170 NA 0.49 6.24 0.32 1.31e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs56104184 0.775 rs73063505 chr19:49402765 T/C cg21252483 chr19:49399788 TULP2 -1.06 -12.19 -0.55 1.27e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs2288073 0.801 rs72797831 chr2:24366829 G/A cg06627628 chr2:24431161 ITSN2 -0.52 -6.85 -0.35 3.49e-11 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.92 -0.3 8e-9 Total body bone mineral density; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg21747090 chr2:27597821 SNX17 -0.44 -6.71 -0.34 8.05e-11 Total body bone mineral density; LIHC cis rs74233809 1.000 rs11191499 chr10:104764271 A/G cg03493300 chr10:104813866 CNNM2 0.47 6.48 0.33 3.15e-10 Birth weight; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14108394 chr12:62997291 MIRLET7I;C12orf61 -0.44 -6.52 -0.33 2.51e-10 Pancreatic cancer; LIHC cis rs611744 0.647 rs1584373 chr8:109263399 C/A cg21045802 chr8:109455806 TTC35 0.59 10.51 0.49 1.41e-22 Dupuytren's disease; LIHC cis rs1707322 0.721 rs11211178 chr1:46227566 G/T cg06784218 chr1:46089804 CCDC17 0.42 7.71 0.38 1.4e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28735056 0.591 rs2277724 chr18:77694294 C/A cg20368463 chr18:77673604 PQLC1 -0.54 -10.3 -0.49 7.38e-22 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25525087 chr17:17743565 NA -0.46 -6.46 -0.33 3.63e-10 Pancreatic cancer; LIHC cis rs1200821 0.529 rs2475206 chr10:37802532 A/G cg00409905 chr10:38381863 ZNF37A 0.44 7.04 0.36 1.07e-11 Hemostatic factors and hematological phenotypes; LIHC cis rs57221529 0.608 rs11749927 chr5:668842 C/T cg09021430 chr5:549028 NA -0.36 -7.66 -0.38 1.98e-13 Lung disease severity in cystic fibrosis; LIHC cis rs1577917 0.682 rs1173419 chr6:86402163 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.36 -6.77 -0.34 5.61e-11 Response to antipsychotic treatment; LIHC cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg03806693 chr22:41940476 POLR3H -0.95 -10.89 -0.51 6.74e-24 Vitiligo; LIHC cis rs7188697 0.922 rs37060 chr16:58566304 C/T cg02549819 chr16:58548995 SETD6 -0.43 -6.84 -0.35 3.6e-11 QT interval; LIHC cis rs2576037 0.901 rs2571021 chr18:44583498 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.44 -6.49 -0.33 2.94e-10 Personality dimensions; LIHC trans rs11098499 0.863 rs9884402 chr4:120489982 A/G cg25214090 chr10:38739885 LOC399744 0.57 9.39 0.45 9.01e-19 Corneal astigmatism; LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg02990361 chr1:107599529 PRMT6 0.65 11.07 0.51 1.48e-24 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs875971 0.660 rs801190 chr7:66033033 C/T cg26939375 chr7:64535504 NA -0.43 -6.94 -0.35 2.02e-11 Aortic root size; LIHC cis rs12477438 0.520 rs7605843 chr2:99811894 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 13.11 0.58 4.31e-32 Chronic sinus infection; LIHC cis rs11864453 0.647 rs9941346 chr16:72135707 C/G cg01557791 chr16:72042693 DHODH -0.45 -7.52 -0.38 4.95e-13 Fibrinogen levels; LIHC cis rs7319311 0.565 rs9588148 chr13:111021081 G/T cg05272587 chr13:111038400 COL4A2 0.36 7.37 0.37 1.31e-12 Bipolar disorder and schizophrenia; LIHC cis rs17445774 1.000 rs17445774 chr2:200859249 A/G cg23649088 chr2:200775458 C2orf69 -0.66 -7.88 -0.39 4.4e-14 LDL cholesterol to HDL cholesterol ratio; LIHC cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg20090690 chr10:134436459 INPP5A 0.45 5.99 0.31 5.44e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4713118 0.662 rs469228 chr6:27970704 A/G cg16479474 chr6:28041457 NA 0.43 6.65 0.34 1.15e-10 Parkinson's disease; LIHC cis rs7395581 0.959 rs901746 chr11:47260319 A/G cg26139080 chr11:47293733 MADD -0.48 -8.03 -0.4 1.63e-14 HDL cholesterol; LIHC cis rs826838 1.000 rs826851 chr12:39112639 A/G cg26384229 chr12:38710491 ALG10B -0.65 -9.6 -0.46 1.79e-19 Heart rate; LIHC cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg03351412 chr1:154909251 PMVK 0.72 10.6 0.5 6.95e-23 Prostate cancer; LIHC cis rs12286929 0.669 rs11606837 chr11:115042837 C/T cg04055981 chr11:115044050 NA 0.53 8.51 0.42 5.53e-16 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10752881 0.935 rs10797834 chr1:183048749 T/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.91e-23 Colorectal cancer; LIHC cis rs10504229 1.000 rs59708460 chr8:58196526 G/A cg02290350 chr8:58132656 NA 0.47 9.11 0.44 7.19e-18 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg12379764 chr21:47803548 PCNT 0.58 8.73 0.43 1.16e-16 Testicular germ cell tumor; LIHC cis rs17401966 0.838 rs4846207 chr1:10313811 T/C cg15208524 chr1:10270712 KIF1B 0.37 5.71 0.3 2.46e-8 Hepatocellular carcinoma; LIHC cis rs1816752 0.870 rs9511261 chr13:25012018 C/T cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.78e-10 Obesity-related traits; LIHC cis rs765787 0.530 rs4238377 chr15:45541981 A/G cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC trans rs4332037 0.619 rs78443464 chr7:1970229 C/T cg11693508 chr17:37793320 STARD3 0.78 7.98 0.4 2.19e-14 Bipolar disorder; LIHC trans rs1875517 0.510 rs11721241 chr3:117329656 A/C cg18115495 chr7:65579946 CRCP -0.41 -6.36 -0.33 6.58e-10 Waist circumference; LIHC cis rs13108904 0.539 rs13141169 chr4:1340353 C/T cg00684032 chr4:1343700 KIAA1530 0.59 8.57 0.42 3.54e-16 Obesity-related traits; LIHC cis rs2073300 1.000 rs6048827 chr20:23458080 T/C cg12062639 chr20:23401060 NAPB 0.82 10.06 0.48 4.89e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs11098499 0.863 rs7669520 chr4:120515278 T/C cg25214090 chr10:38739885 LOC399744 0.57 9.35 0.45 1.15e-18 Corneal astigmatism; LIHC cis rs933688 0.583 rs10036206 chr5:90609178 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.47 6.85 0.35 3.41e-11 Smoking behavior; LIHC cis rs10193935 0.901 rs13375 chr2:42559288 A/G cg27598129 chr2:42591480 NA -0.72 -11.39 -0.52 1.11e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs4917833 0.738 rs7067713 chr10:100221120 T/C cg19043522 chr10:100227446 HPSE2 0.4 5.76 0.3 1.83e-8 Pediatric bone mineral density (femoral neck); LIHC trans rs4332037 1.000 rs4332037 chr7:1950809 C/T cg11693508 chr17:37793320 STARD3 0.66 7.0 0.35 1.4e-11 Bipolar disorder; LIHC trans rs7395662 0.517 rs2021248 chr11:49013054 C/T cg03929089 chr4:120376271 NA -0.44 -6.46 -0.33 3.57e-10 HDL cholesterol; LIHC cis rs933688 1.000 rs6867219 chr5:90718008 T/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.61 0.67 7.88e-46 Smoking behavior; LIHC cis rs896854 0.812 rs4582532 chr8:95969257 G/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.94 -0.39 2.89e-14 Type 2 diabetes; LIHC cis rs875971 0.862 rs10263690 chr7:65766453 G/C cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs826838 0.967 rs1684414 chr12:39129553 A/G cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs11583043 0.958 rs12730160 chr1:101438791 G/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.49 5.95 0.31 6.5e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4407350 0.870 rs4823329 chr22:44910117 T/C cg26276947 chr22:44892394 LDOC1L 0.34 6.56 0.33 1.99e-10 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs1498312 chr1:76177849 C/T cg10523679 chr1:76189770 ACADM 0.66 9.12 0.44 6.78e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1005277 0.579 rs1614236 chr10:38502996 C/T cg00409905 chr10:38381863 ZNF37A -0.57 -9.46 -0.46 5.22e-19 Extrinsic epigenetic age acceleration; LIHC cis rs34779708 0.966 rs10827492 chr10:35429825 A/G cg04310649 chr10:35416472 CREM 0.42 5.75 0.3 1.95e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs921968 0.509 rs10932782 chr2:219353195 C/T cg02985541 chr2:219472218 PLCD4 0.43 6.95 0.35 1.84e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs801193 0.967 rs2707849 chr7:66152712 T/C cg00343986 chr7:65444356 GUSB 0.39 5.85 0.3 1.14e-8 Aortic root size; LIHC cis rs921968 0.643 rs508157 chr2:219435288 G/A cg17980119 chr2:219472607 PLCD4 0.34 5.74 0.3 2.08e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs11098499 0.909 rs7681214 chr4:120385320 C/A cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs7264396 0.623 rs11698601 chr20:34205035 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -8.82 -0.43 5.91e-17 Total cholesterol levels; LIHC cis rs868036 0.681 rs1026737 chr15:68107072 A/C cg24579218 chr15:68104479 NA -0.34 -5.77 -0.3 1.81e-8 Restless legs syndrome; LIHC cis rs546131 0.928 rs552171 chr11:34830709 G/T cg11058730 chr11:34937778 PDHX;APIP 0.64 9.39 0.45 8.48e-19 Lung disease severity in cystic fibrosis; LIHC trans rs3960554 0.600 rs2302429 chr7:75614777 G/A cg19862616 chr7:65841803 NCRNA00174 0.53 6.84 0.35 3.65e-11 Eotaxin levels; LIHC cis rs2153535 0.541 rs6932434 chr6:8467679 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC trans rs916888 0.821 rs199499 chr17:44865498 C/T cg26692224 chr17:62915920 LRRC37A3 -0.76 -6.27 -0.32 1.11e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs10506458 0.915 rs12426308 chr12:63405778 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.73 -10.39 -0.49 3.73e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs600806 0.683 rs10857789 chr1:110012293 C/T cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.48 -0.38 6.2e-13 Intelligence (multi-trait analysis); LIHC cis rs2731664 0.792 rs337374 chr5:176890416 A/G cg23176889 chr5:176863531 GRK6 0.68 12.32 0.55 4.25e-29 Intelligence (multi-trait analysis); LIHC cis rs7116495 0.609 rs4945378 chr11:71668866 G/A cg10381502 chr11:71823885 C11orf51 -1.02 -8.51 -0.42 5.38e-16 Severe influenza A (H1N1) infection; LIHC cis rs9309473 1.000 rs13398956 chr2:73720258 C/A cg20560298 chr2:73613845 ALMS1 -0.56 -6.5 -0.33 2.87e-10 Metabolite levels; LIHC cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg06481639 chr22:41940642 POLR3H -0.7 -7.15 -0.36 5.16e-12 Vitiligo; LIHC cis rs7618501 1.000 rs7618501 chr3:49772647 A/G cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC trans rs1147813 0.654 rs993232 chr9:25890597 A/G cg08816869 chr17:79829959 ARHGDIA 0.49 6.08 0.31 3.18e-9 Morning vs. evening chronotype; LIHC cis rs4268898 0.722 rs35520052 chr2:24415277 C/T cg06627628 chr2:24431161 ITSN2 0.49 7.07 0.36 8.72e-12 Asthma; LIHC trans rs4604234 0.803 rs73463522 chr6:80979758 A/G cg08069338 chr6:160207898 SNORA29;TCP1 0.64 6.2 0.32 1.63e-9 Cancer; LIHC trans rs1814175 0.527 rs3974435 chr11:49619533 G/A cg03929089 chr4:120376271 NA -0.67 -9.83 -0.47 3.09e-20 Height; LIHC cis rs11122272 0.735 rs2437150 chr1:231488524 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.65 10.65 0.5 4.46e-23 Hemoglobin concentration; LIHC cis rs655641 1.000 rs547767 chr11:85743449 A/G cg09030501 chr11:85779252 PICALM -0.54 -6.22 -0.32 1.45e-9 Platelet count; LIHC cis rs3770081 1.000 rs17026854 chr2:86280496 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.85 -8.88 -0.43 3.77e-17 Facial emotion recognition (sad faces); LIHC cis rs17401966 0.931 rs17034821 chr1:10414645 A/G cg19773385 chr1:10388646 KIF1B -0.4 -6.81 -0.35 4.5e-11 Hepatocellular carcinoma; LIHC cis rs769267 0.895 rs2315279 chr19:19479936 C/A cg26732615 chr19:19648335 CILP2;YJEFN3 -0.39 -5.94 -0.31 6.83e-9 Tonsillectomy; LIHC cis rs4919087 0.590 rs1253396 chr10:99045230 C/T cg25902810 chr10:99078978 FRAT1 -0.6 -6.79 -0.34 4.92e-11 Monocyte count; LIHC cis rs6964587 0.610 rs2888850 chr7:91430027 T/C cg17063962 chr7:91808500 NA 0.65 10.79 0.5 1.54e-23 Breast cancer; LIHC cis rs17685 0.753 rs6464999 chr7:75787315 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9896052 0.614 rs4073989 chr17:73450862 G/A cg25649188 chr17:73499917 CASKIN2 0.46 6.92 0.35 2.21e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs597539 0.652 rs627731 chr11:68698663 A/C cg06028808 chr11:68637592 NA 0.45 5.82 0.3 1.36e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs763014 1.000 rs763014 chr16:675680 T/C cg00908189 chr16:619842 PIGQ 0.83 13.13 0.58 3.52e-32 Height; LIHC cis rs965469 0.779 rs3746630 chr20:3320902 C/T cg25506879 chr20:3388711 C20orf194 -0.54 -6.63 -0.34 1.33e-10 IFN-related cytopenia; LIHC cis rs2777491 0.957 rs16971798 chr15:41657144 A/T cg18705301 chr15:41695430 NDUFAF1 0.59 9.12 0.44 6.8e-18 Ulcerative colitis; LIHC cis rs9790314 0.747 rs7619011 chr3:160855676 A/G cg03342759 chr3:160939853 NMD3 -0.68 -9.36 -0.45 1.08e-18 Morning vs. evening chronotype; LIHC cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg12311346 chr5:56204834 C5orf35 -0.56 -7.35 -0.37 1.45e-12 Initial pursuit acceleration; LIHC cis rs7552404 0.924 rs7544117 chr1:76158246 A/G cg03433033 chr1:76189801 ACADM 0.69 10.58 0.5 8e-23 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs4906332 0.966 rs7401563 chr14:103964425 G/A cg17675199 chr6:35436792 RPL10A 0.34 6.76 0.34 6.06e-11 Coronary artery disease; LIHC cis rs274567 0.602 rs272853 chr5:131688561 A/G cg24060327 chr5:131705240 SLC22A5 -0.77 -12.11 -0.55 2.38e-28 Blood metabolite levels; LIHC cis rs35883536 0.647 rs2783703 chr1:101040794 T/C cg14515779 chr1:101123966 NA -0.45 -6.38 -0.33 5.67e-10 Monocyte count; LIHC cis rs4555082 0.756 rs76863138 chr14:105736379 C/T cg06808227 chr14:105710500 BRF1 -0.56 -7.24 -0.36 3.03e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs17756712 0.528 rs2073007 chr6:638267 C/T cg14374089 chr6:596013 EXOC2 -0.44 -5.74 -0.3 2.14e-8 Vertical cup-disc ratio; LIHC trans rs7618501 1.000 rs7374277 chr3:49784777 T/C cg21659725 chr3:3221576 CRBN -0.99 -19.67 -0.73 3.83e-58 Intelligence (multi-trait analysis); LIHC cis rs2839627 0.561 rs2839601 chr21:44317381 A/G cg03543861 chr21:44258195 NA 0.54 7.94 0.39 2.92e-14 Information processing speed; LIHC cis rs1904096 0.506 rs6532476 chr4:95192461 C/A cg11021082 chr4:95130006 SMARCAD1 -0.5 -9.33 -0.45 1.33e-18 Type 2 diabetes; LIHC cis rs9583531 0.527 rs12875067 chr13:111365104 A/G cg24331049 chr13:111365604 ING1 0.78 13.23 0.58 1.48e-32 Coronary artery disease; LIHC cis rs6964587 0.621 rs38799 chr7:92045139 C/T cg17063962 chr7:91808500 NA -0.61 -9.96 -0.47 1.09e-20 Breast cancer; LIHC cis rs1059312 1.000 rs12814773 chr12:129280786 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.73 -14.43 -0.62 3.3e-37 Systemic lupus erythematosus; LIHC cis rs4665809 0.549 rs72809635 chr2:26411674 G/A cg27170947 chr2:26402098 FAM59B 0.61 6.34 0.32 7.31e-10 Gut microbiome composition (summer); LIHC cis rs7149337 0.717 rs4309324 chr14:51606336 A/T cg23942311 chr14:51606299 NA -0.39 -8.32 -0.41 2.17e-15 Cancer; LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg05552183 chr6:42928497 GNMT 0.68 10.12 0.48 3.11e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs11888559 0.655 rs13397552 chr2:203969436 C/T cg24605529 chr2:203879461 NBEAL1 0.78 5.92 0.3 7.94e-9 Height; LIHC cis rs769267 1.000 rs2074090 chr19:19449686 G/T cg03709012 chr19:19516395 GATAD2A -0.92 -16.02 -0.65 1.72e-43 Tonsillectomy; LIHC cis rs9420 0.925 rs10896636 chr11:57448032 C/G cg19752551 chr11:57585705 CTNND1 -0.49 -6.76 -0.34 6.14e-11 Schizophrenia; LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.65 -11.42 -0.53 8.01e-26 Prudent dietary pattern; LIHC cis rs151997 1.000 rs32483 chr5:50205230 C/T cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs2836974 0.644 rs719230 chr21:40676307 C/T cg17971929 chr21:40555470 PSMG1 -0.48 -7.08 -0.36 8.34e-12 Cognitive function; LIHC cis rs600806 0.850 rs7518013 chr1:109944078 C/T cg02415029 chr1:110025642 ATXN7L2 0.45 5.73 0.3 2.23e-8 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.931 rs13064911 chr3:48952385 A/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.2 0.36 3.92e-12 Parkinson's disease; LIHC cis rs2439831 0.702 rs8033995 chr15:44013509 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.48 5.99 0.31 5.25e-9 Lung cancer in ever smokers; LIHC cis rs921968 0.541 rs3755041 chr2:219442499 A/T cg02985541 chr2:219472218 PLCD4 -0.4 -6.46 -0.33 3.59e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs904251 0.523 rs2797796 chr6:37480886 T/C cg25019722 chr6:37503610 NA -0.32 -5.74 -0.3 2.07e-8 Cognitive performance; LIHC cis rs9916302 0.904 rs9898170 chr17:37510092 T/C cg00129232 chr17:37814104 STARD3 0.38 6.11 0.31 2.67e-9 Glomerular filtration rate (creatinine); LIHC cis rs6674970 0.748 rs56299877 chr1:151115645 C/T cg11822372 chr1:151115635 SEMA6C -0.92 -10.7 -0.5 3.15e-23 Childhood ear infection; LIHC cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg04025307 chr7:1156635 C7orf50 0.63 10.9 0.51 5.98e-24 Longevity;Endometriosis; LIHC cis rs9291683 0.552 rs11736410 chr4:10017241 G/A cg11266682 chr4:10021025 SLC2A9 0.33 6.98 0.35 1.59e-11 Bone mineral density; LIHC cis rs7552404 0.924 rs1498317 chr1:76171984 A/C cg03433033 chr1:76189801 ACADM 0.68 10.47 0.49 1.89e-22 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9457247 1.000 rs2757047 chr6:167374489 C/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.93 -0.47 1.42e-20 Crohn's disease; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg01125608 chr5:646071 CEP72 0.42 6.16 0.32 2.08e-9 Bilirubin levels; LIHC cis rs6952808 0.594 rs3778965 chr7:2138296 G/A cg02951883 chr7:2050386 MAD1L1 -0.65 -10.67 -0.5 3.98e-23 Bipolar disorder and schizophrenia; LIHC cis rs9443189 0.615 rs618239 chr6:76350038 A/G cg01950844 chr6:76311363 SENP6 0.88 10.95 0.51 4.09e-24 Prostate cancer; LIHC trans rs975809 0.966 rs11004607 chr10:56622686 G/T cg09782621 chr19:56653147 ZNF444 0.39 6.16 0.32 2.09e-9 Carotid intima media thickness; LIHC cis rs8060686 0.920 rs73593810 chr16:67866783 C/T cg05110241 chr16:68378359 PRMT7 -0.64 -5.72 -0.3 2.29e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs3020736 0.500 rs2413669 chr22:42507748 A/C cg04733989 chr22:42467013 NAGA -0.64 -9.18 -0.44 4.09e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs9790314 0.967 rs336586 chr3:161081347 G/A cg03342759 chr3:160939853 NMD3 -0.7 -8.33 -0.41 2.02e-15 Morning vs. evening chronotype; LIHC cis rs17106184 1.000 rs12096626 chr1:51286155 G/A cg07174182 chr1:51127561 FAF1 -0.65 -7.21 -0.36 3.53e-12 Type 2 diabetes; LIHC cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.76 5.84 0.3 1.24e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs783540 0.934 rs4779050 chr15:83368738 T/G cg18393722 chr15:85113863 UBE2QP1 0.37 6.45 0.33 3.72e-10 Schizophrenia; LIHC cis rs332507 0.830 rs35816663 chr3:124405513 G/T cg05980111 chr3:124395277 KALRN 0.45 6.88 0.35 2.9100000000000002e-11 Plateletcrit; LIHC cis rs3736485 0.966 rs12441167 chr15:51850652 T/C cg08986416 chr15:51914746 DMXL2 -0.4 -5.74 -0.3 2.12e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs939574 0.790 rs72955440 chr2:220091765 A/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.87 6.36 0.33 6.41e-10 Platelet distribution width; LIHC cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.55 -9.37 -0.45 9.77e-19 Bipolar disorder; LIHC cis rs1577917 0.958 rs66807489 chr6:86440702 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.27 -0.32 1.1e-9 Response to antipsychotic treatment; LIHC trans rs1814175 0.692 rs1851873 chr11:49937767 A/G cg15704280 chr7:45808275 SEPT13 -0.71 -12.15 -0.55 1.7e-28 Height; LIHC cis rs6963495 0.818 rs6961863 chr7:105180953 C/T cg19920283 chr7:105172520 RINT1 0.66 6.42 0.33 4.55e-10 Bipolar disorder (body mass index interaction); LIHC cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg08645402 chr16:4508243 NA 0.42 7.92 0.39 3.41e-14 Schizophrenia; LIHC cis rs9522267 0.535 rs9522302 chr13:112236874 C/T cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC trans rs4596713 0.508 rs59620993 chr9:71771911 C/T cg16512924 chr15:28394682 HERC2 0.4 6.47 0.33 3.43e-10 Headache; LIHC trans rs1814175 0.588 rs7481648 chr11:49754910 A/G cg15704280 chr7:45808275 SEPT13 -0.97 -20.37 -0.74 5.91e-61 Height; LIHC cis rs875971 0.619 rs2302918 chr7:66000932 A/G cg11764359 chr7:65958608 NA 0.72 10.95 0.51 4.14e-24 Aortic root size; LIHC cis rs7927771 0.542 rs10769300 chr11:47865560 C/T cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC trans rs875971 0.502 rs1796227 chr7:66087019 G/C cg26939375 chr7:64535504 NA -0.39 -6.12 -0.31 2.57e-9 Aortic root size; LIHC cis rs2637266 0.626 rs2588329 chr10:78552782 C/T cg18941641 chr10:78392320 NA 0.3 6.55 0.33 2.14e-10 Pulmonary function; LIHC cis rs738321 0.756 rs11089863 chr22:38512402 G/A cg25457927 chr22:38595422 NA -0.29 -6.47 -0.33 3.49e-10 Breast cancer; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg24846343 chr22:24311635 DDTL 0.66 13.14 0.58 3.42e-32 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7927592 0.763 rs10791982 chr11:68337664 T/G cg20283391 chr11:68216788 NA 0.36 5.74 0.3 2.12e-8 Total body bone mineral density; LIHC trans rs17586843 0.528 rs13119466 chr4:116805008 C/G cg25881869 chr10:114609298 LOC143188 0.41 6.15 0.32 2.18e-9 Age-related macular degeneration; LIHC cis rs11252926 0.545 rs10466270 chr10:556129 A/G cg09445902 chr10:555545 DIP2C -0.4 -6.48 -0.33 3.17e-10 Psychosis in Alzheimer's disease; LIHC trans rs7666738 0.830 rs4292341 chr4:98959724 C/T cg16398128 chr5:16465888 ZNF622 0.39 6.24 0.32 1.33e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs8056893 0.842 rs1111571 chr16:68363181 A/G cg02226672 chr16:68398533 SMPD3 -0.43 -6.17 -0.32 1.89e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs965469 0.779 rs2236112 chr20:3294983 C/G cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs10256972 0.669 rs10229964 chr7:1051776 A/G cg23978390 chr7:1156363 C7orf50 0.42 6.16 0.32 2.02e-9 Longevity;Endometriosis; LIHC trans rs2363709 1.000 rs2363714 chr3:67421846 C/G cg25028035 chr6:42016671 CCND3 0.83 6.16 0.32 2.04e-9 IgE levels; LIHC cis rs6570726 0.967 rs373704 chr6:145860618 C/A cg23711669 chr6:146136114 FBXO30 0.53 9.29 0.45 1.79e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs7582180 0.764 rs11691684 chr2:100921776 T/A cg14675211 chr2:100938903 LONRF2 0.51 7.69 0.38 1.59e-13 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg13395646 chr4:1353034 KIAA1530 -0.65 -9.37 -0.45 1.05e-18 Obesity-related traits; LIHC cis rs2842992 0.662 rs2273825 chr6:160211424 A/C cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.14 0.44 5.61e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs8027181 0.804 rs34661924 chr15:72994564 A/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.49 7.65 0.38 2.12e-13 Triglyceride levels; LIHC cis rs12142240 0.667 rs66990604 chr1:46822073 G/A cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs7208859 0.673 rs2470251 chr17:29095061 T/C cg13385521 chr17:29058706 SUZ12P 0.8 8.14 0.4 7.44e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7903847 0.642 rs9888026 chr10:99159869 G/T cg06359132 chr10:99160096 RRP12 0.41 6.38 0.33 5.64e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs28374715 0.532 rs316607 chr15:41772693 G/A cg18705301 chr15:41695430 NDUFAF1 -1.25 -17.87 -0.69 6.28e-51 Ulcerative colitis; LIHC cis rs295140 0.605 rs10931893 chr2:201114652 A/G cg23649088 chr2:200775458 C2orf69 -0.44 -6.12 -0.31 2.59e-9 QT interval; LIHC cis rs8044995 0.563 rs56220628 chr16:68384837 G/A cg03983715 chr16:68378420 PRMT7 -0.53 -6.45 -0.33 3.8e-10 Schizophrenia; LIHC cis rs595982 0.546 rs9941490 chr19:49396737 G/A cg21252483 chr19:49399788 TULP2 -0.6 -9.41 -0.45 7.76e-19 Red cell distribution width; LIHC cis rs11212260 0.655 rs11212234 chr11:107306877 C/A cg25435332 chr11:107328525 CWF19L2 0.82 8.3 0.41 2.4e-15 IgG glycosylation; LIHC trans rs9858542 1.000 rs9858542 chr3:49701983 A/G cg21659725 chr3:3221576 CRBN 0.54 6.04 0.31 4.01e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs12286929 0.646 rs12805914 chr11:115019739 T/A cg04055981 chr11:115044050 NA 0.38 5.72 0.3 2.39e-8 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4819052 0.807 rs4819047 chr21:46665139 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.55 0.53 2.91e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9486719 0.947 rs11755945 chr6:96908038 G/C cg06623918 chr6:96969491 KIAA0776 -0.71 -7.13 -0.36 6.08e-12 Migraine;Coronary artery disease; LIHC trans rs11098499 1.000 rs10029750 chr4:120172543 A/G cg25214090 chr10:38739885 LOC399744 0.52 7.92 0.39 3.35e-14 Corneal astigmatism; LIHC cis rs9911578 1.000 rs8076121 chr17:57041699 G/A cg05425664 chr17:57184151 TRIM37 -0.59 -8.79 -0.43 7.66e-17 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.500 rs34703942 chr12:34583776 T/C cg26384229 chr12:38710491 ALG10B -0.62 -7.76 -0.39 1.01e-13 Morning vs. evening chronotype; LIHC cis rs3106136 0.772 rs2865353 chr4:95270878 T/C cg11021082 chr4:95130006 SMARCAD1 0.41 7.32 0.37 1.73e-12 Capecitabine sensitivity; LIHC trans rs637571 0.780 rs653914 chr11:65676516 A/G cg17712092 chr4:129076599 LARP1B 0.9 16.89 0.67 5.5e-47 Eosinophil percentage of white cells; LIHC cis rs4319547 0.876 rs10846978 chr12:122964708 T/C cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.2 -0.41 4.94e-15 Body mass index; LIHC cis rs11122272 0.735 rs2486729 chr1:231535584 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.53 -0.49 1.17e-22 Hemoglobin concentration; LIHC cis rs57677839 1 rs57677839 chr11:17028189 G/A cg15084286 chr11:17036142 PLEKHA7 0.94 13.55 0.59 8.74e-34 Coronary artery disease; LIHC cis rs10489202 1.000 rs67600256 chr1:167972357 T/C cg24449463 chr1:168025552 DCAF6 -0.52 -6.5 -0.33 2.9e-10 Schizophrenia; LIHC cis rs7917772 0.636 rs7911747 chr10:104528890 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -5.78 -0.3 1.66e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4808199 0.649 rs12983940 chr19:19516431 G/A cg03709012 chr19:19516395 GATAD2A 1.08 19.26 0.72 1.67e-56 Nonalcoholic fatty liver disease; LIHC cis rs26949 0.511 rs1562235 chr5:59877538 T/G cg02684056 chr5:59996105 DEPDC1B 0.4 5.93 0.31 7.57e-9 Intelligence (multi-trait analysis); LIHC cis rs858239 0.601 rs6969733 chr7:23168377 T/C cg23682824 chr7:23144976 KLHL7 0.39 5.83 0.3 1.26e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs801193 0.591 rs2707839 chr7:66193084 A/G cg18876405 chr7:65276391 NA 0.34 6.21 0.32 1.53e-9 Aortic root size; LIHC cis rs17253792 0.822 rs10136155 chr14:56049129 G/A cg01858014 chr14:56050164 KTN1 -0.75 -8.07 -0.4 1.22e-14 Putamen volume; LIHC cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg23283495 chr1:209979779 IRF6 -0.45 -7.18 -0.36 4.3e-12 Cleft lip with or without cleft palate; LIHC cis rs6442522 0.640 rs13095087 chr3:15518841 A/G cg16303742 chr3:15540471 COLQ -0.41 -6.63 -0.34 1.3e-10 Uric acid levels; LIHC cis rs1215050 0.904 rs2903153 chr4:99057457 C/T cg05340658 chr4:99064831 C4orf37 0.42 6.24 0.32 1.27e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9790314 1.000 rs336579 chr3:161086610 G/A cg03342759 chr3:160939853 NMD3 -0.67 -7.93 -0.39 3.24e-14 Morning vs. evening chronotype; LIHC cis rs743757 0.878 rs1467913 chr3:50525017 G/T cg09545109 chr3:50388910 TUSC4;CYB561D2 0.46 7.05 0.36 1.02e-11 Diastolic blood pressure; LIHC cis rs911119 1.000 rs67567111 chr20:23619075 G/T cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs9921222 0.542 rs9926968 chr16:381561 A/C cg26944245 chr16:421049 TMEM8A;MRPL28 0.41 7.01 0.35 1.27e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs910316 0.503 rs12894709 chr14:75441734 G/A cg11812906 chr14:75593930 NEK9 0.69 12.4 0.56 2.1e-29 Height; LIHC cis rs2116941 1.000 rs7250265 chr19:10339818 G/C cg01850179 chr19:10340795 S1PR2 -0.57 -9.27 -0.45 2.1e-18 Pulse pressure; LIHC trans rs877282 0.945 rs34367686 chr10:791868 G/C cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg10920230 chr7:150757210 SLC4A2 0.54 6.31 0.32 8.79e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs72843506 0.722 rs117096120 chr17:20167693 G/A cg12065943 chr17:19881925 AKAP10 -0.38 -6.34 -0.32 7.14e-10 Schizophrenia; LIHC cis rs4555082 0.834 rs2735826 chr14:105710866 G/A cg06808227 chr14:105710500 BRF1 -0.49 -6.14 -0.32 2.23e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs12701220 0.696 rs12112029 chr7:1137889 G/A cg16145915 chr7:1198662 ZFAND2A -0.35 -6.94 -0.35 1.95e-11 Bronchopulmonary dysplasia; LIHC trans rs3942852 0.726 rs10742836 chr11:48175831 G/A cg15704280 chr7:45808275 SEPT13 -0.59 -8.01 -0.4 1.77e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs875971 0.545 rs2279757 chr7:65828663 T/C cg11764359 chr7:65958608 NA 0.6 8.43 0.41 1.01e-15 Aortic root size; LIHC cis rs4665809 0.877 rs35224700 chr2:26298037 T/C cg26119090 chr2:26468346 HADHA;HADHB 0.71 7.74 0.39 1.17e-13 Gut microbiome composition (summer); LIHC cis rs317689 0.718 rs645026 chr12:69757931 G/A cg20891283 chr12:69753455 YEATS4 0.68 10.67 0.5 3.83e-23 Response to diuretic therapy; LIHC cis rs6450176 0.951 rs5013866 chr5:53300947 A/G ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6964587 0.839 rs17731846 chr7:91440342 A/G cg17063962 chr7:91808500 NA 0.96 17.52 0.69 1.76e-49 Breast cancer; LIHC cis rs28374715 0.532 rs28703570 chr15:41679492 G/A cg18705301 chr15:41695430 NDUFAF1 -1.23 -18.59 -0.71 8.2e-54 Ulcerative colitis; LIHC cis rs3892630 0.824 rs2287882 chr19:33332952 C/T cg22980127 chr19:33182716 NUDT19 0.99 11.8 0.54 3.46e-27 Red blood cell traits; LIHC cis rs7937682 0.883 rs12366001 chr11:111433916 A/G cg09085632 chr11:111637200 PPP2R1B 0.9 10.79 0.5 1.52e-23 Primary sclerosing cholangitis; LIHC cis rs7772486 0.790 rs6917482 chr6:146243581 C/T cg13319975 chr6:146136371 FBXO30 0.35 5.78 0.3 1.66e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs801193 0.844 rs2244022 chr7:66202430 A/G cg26939375 chr7:64535504 NA 0.42 7.03 0.36 1.13e-11 Aortic root size; LIHC cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg25894440 chr7:65020034 NA -0.53 -6.17 -0.32 1.93e-9 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03402805 chr12:2921865 ITFG2 -0.46 -6.49 -0.33 2.99e-10 Pancreatic cancer; LIHC cis rs72781680 0.950 rs72796402 chr2:24180104 A/G cg08917208 chr2:24149416 ATAD2B 0.96 8.25 0.41 3.52e-15 Lymphocyte counts; LIHC cis rs10744422 0.925 rs897391 chr12:123326374 G/A cg18912006 chr12:123335444 HIP1R -0.58 -7.11 -0.36 6.8e-12 Schizophrenia; LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg06873352 chr17:61820015 STRADA 0.75 13.58 0.59 6.97e-34 Prudent dietary pattern; LIHC cis rs919433 0.647 rs13404366 chr2:198522632 A/G cg10820045 chr2:198174542 NA 0.46 7.18 0.36 4.27e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1707322 0.890 rs2297883 chr1:46511487 G/C cg03146154 chr1:46216737 IPP -0.45 -7.4 -0.37 1.05e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4665809 0.878 rs6720312 chr2:26364934 A/G cg27170947 chr2:26402098 FAM59B 0.66 8.28 0.41 2.77e-15 Gut microbiome composition (summer); LIHC cis rs1008375 0.931 rs6813374 chr4:17649494 T/C cg15017067 chr4:17643749 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4934494 0.768 rs11330 chr10:91394079 G/T cg19698084 chr10:91461284 KIF20B 0.47 6.43 0.33 4.31e-10 Red blood cell count; LIHC cis rs2439831 0.867 rs2264876 chr15:43757419 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.96 0.44 2.2e-17 Lung cancer in ever smokers; LIHC cis rs1023500 0.573 rs133381 chr22:42470608 C/G cg15557168 chr22:42548783 NA -0.44 -6.96 -0.35 1.75e-11 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08674093 chr3:182697846 DCUN1D1 0.44 6.07 0.31 3.43e-9 Hepatitis; LIHC cis rs782590 0.902 rs782595 chr2:55845596 C/G cg03859395 chr2:55845619 SMEK2 0.94 17.02 0.68 1.66e-47 Metabolic syndrome; LIHC trans rs911119 0.657 rs2145231 chr20:23625547 A/G cg23114964 chr1:42217077 HIVEP3 -0.43 -6.71 -0.34 8.26e-11 Chronic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20449327 chr14:59951241 C14orf149;JKAMP 0.48 6.22 0.32 1.42e-9 Lung function (FEV1/FVC); LIHC cis rs4788570 0.615 rs7206470 chr16:71668800 G/A cg06353428 chr16:71660113 MARVELD3 1.44 15.41 0.64 4.85e-41 Intelligence (multi-trait analysis); LIHC trans rs7690819 0.589 rs12505855 chr4:112131601 A/C cg06972903 chr1:6580525 PLEKHG5 0.37 6.32 0.32 7.95e-10 Medication adherence in chronic diseases; LIHC cis rs7959452 0.640 rs10878957 chr12:69699638 G/C cg14784868 chr12:69753453 YEATS4 0.88 16.95 0.68 3.41e-47 Blood protein levels; LIHC cis rs4665809 1.000 rs6729080 chr2:26301282 G/A cg27170947 chr2:26402098 FAM59B -0.62 -7.72 -0.39 1.27e-13 Gut microbiome composition (summer); LIHC cis rs113352275 1 rs113352275 chr15:78840567 C/T cg06917634 chr15:78832804 PSMA4 -0.58 -7.24 -0.36 3.03e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg12463550 chr7:65579703 CRCP 0.67 7.02 0.36 1.17e-11 Diabetic kidney disease; LIHC cis rs2760061 0.626 rs596675 chr1:228117892 G/A cg01200585 chr1:228362443 C1orf69 -0.41 -5.97 -0.31 6.09e-9 Diastolic blood pressure; LIHC trans rs2273156 0.929 rs4573843 chr14:35391769 A/G cg20620338 chr15:102077239 NA -0.41 -6.04 -0.31 3.97e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs367615 0.512 rs246105 chr5:108672946 C/T cg17395555 chr5:108820864 NA 0.28 5.99 0.31 5.45e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg02290350 chr8:58132656 NA 0.51 11.04 0.51 1.9e-24 Developmental language disorder (linguistic errors); LIHC cis rs7589728 0.563 rs12479338 chr2:88444513 C/T cg04511125 chr2:88470314 THNSL2 0.98 9.92 0.47 1.56e-20 Plasma clusterin levels; LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg02782426 chr3:40428986 ENTPD3 0.34 6.21 0.32 1.51e-9 Renal cell carcinoma; LIHC cis rs1008375 1.000 rs555 chr4:17625658 A/G cg16339924 chr4:17578868 LAP3 0.44 6.15 0.32 2.18e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8017423 0.935 rs12880102 chr14:90793526 G/T cg14092571 chr14:90743983 NA 0.44 6.94 0.35 1.93e-11 Mortality in heart failure; LIHC cis rs6831352 0.838 rs2851250 chr4:100044113 G/C cg12011299 chr4:100065546 ADH4 0.62 10.4 0.49 3.54e-22 Alcohol dependence; LIHC cis rs250677 0.687 rs36046 chr5:148441257 A/C cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg23978390 chr7:1156363 C7orf50 0.65 10.02 0.48 6.9e-21 Longevity;Endometriosis; LIHC cis rs2617583 0.967 rs2652510 chr5:1447860 C/T cg07151155 chr5:1473589 LPCAT1 -0.4 -6.15 -0.32 2.21e-9 Breast cancer; LIHC cis rs7772486 0.875 rs6570736 chr6:146388320 C/T cg13319975 chr6:146136371 FBXO30 -0.36 -6.0 -0.31 4.9e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs3780486 0.801 rs56687083 chr9:33132134 A/G cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs611744 0.905 rs408506 chr8:109154233 A/C cg21045802 chr8:109455806 TTC35 -0.47 -8.17 -0.4 6.13e-15 Dupuytren's disease; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.655 rs34344742 chr7:1149288 C/G cg18765753 chr7:1198926 ZFAND2A -0.43 -6.06 -0.31 3.57e-9 Bronchopulmonary dysplasia; LIHC cis rs10078 0.571 rs2671890 chr5:456457 A/G cg08916839 chr5:415575 AHRR 0.61 12.64 0.56 2.53e-30 Fat distribution (HIV); LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg26338869 chr17:61819248 STRADA 0.6 8.75 0.43 9.91e-17 Prudent dietary pattern; LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs600806 0.778 rs2043059 chr1:109991009 C/A cg11161837 chr1:110010384 SYPL2 0.44 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis); LIHC cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.53 -0.38 4.56e-13 Bipolar disorder; LIHC cis rs72781680 0.848 rs6754694 chr2:24155448 T/C cg08917208 chr2:24149416 ATAD2B 0.85 7.82 0.39 6.77e-14 Lymphocyte counts; LIHC cis rs796364 0.806 rs203767 chr2:200902411 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs2841277 0.771 rs2819469 chr14:105394859 G/A cg15352829 chr14:105391018 PLD4 0.44 8.88 0.43 3.98e-17 Rheumatoid arthritis; LIHC cis rs490234 0.616 rs2648318 chr9:128163447 T/C cg14078157 chr9:128172775 NA -0.44 -7.36 -0.37 1.41e-12 Mean arterial pressure; LIHC cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg18225595 chr11:63971243 STIP1 0.67 8.42 0.41 1.06e-15 Mean platelet volume; LIHC cis rs3770081 1.000 rs2289237 chr2:86266274 C/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.86 9.03 0.44 1.32e-17 Facial emotion recognition (sad faces); LIHC cis rs1707322 0.717 rs28396194 chr1:46213227 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2303745 0.589 rs1965717 chr19:17398559 C/T cg02221750 chr19:17393354 ANKLE1 -0.41 -5.82 -0.3 1.36e-8 Systemic lupus erythematosus; LIHC cis rs1664789 0.844 rs1694062 chr5:53278982 C/T ch.5.1024479R chr5:53302184 ARL15 0.5 7.87 0.39 4.63e-14 Waist circumference adjusted for body mass index; LIHC cis rs80282103 0.867 rs11250242 chr10:1100064 A/C cg18964960 chr10:1102726 WDR37 -0.71 -6.55 -0.33 2.13e-10 Glomerular filtration rate (creatinine); LIHC cis rs7572733 0.515 rs13382697 chr2:198920560 A/C cg10820045 chr2:198174542 NA 0.4 5.92 0.3 7.95e-9 Dermatomyositis; LIHC trans rs2727020 0.930 rs1164686 chr11:49291822 C/T cg15704280 chr7:45808275 SEPT13 0.78 11.75 0.54 5.43e-27 Coronary artery disease; LIHC cis rs3806843 1.000 rs7732179 chr5:140199039 G/A cg26395211 chr5:140044315 WDR55 -0.44 -6.48 -0.33 3.25e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7412746 0.646 rs10399947 chr1:150861960 G/A cg17724175 chr1:150552817 MCL1 0.4 8.0 0.4 1.93e-14 Melanoma; LIHC cis rs62005083 0.500 rs10135300 chr14:74574561 G/T cg05179529 chr14:74551516 LIN52;ALDH6A1 0.53 7.18 0.36 4.26e-12 Mean corpuscular volume; LIHC cis rs3096299 0.802 rs3102336 chr16:89442006 C/T cg08822215 chr16:89438651 ANKRD11 -0.51 -8.19 -0.4 5.23e-15 Multiple myeloma (IgH translocation); LIHC cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg17971929 chr21:40555470 PSMG1 -0.46 -6.91 -0.35 2.45e-11 Cognitive function; LIHC cis rs4742903 0.967 rs4743690 chr9:106909577 T/C cg14250997 chr9:106856677 SMC2 0.4 7.19 0.36 4.21e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs17384381 0.953 rs2076699 chr1:85817295 G/A cg16011679 chr1:85725395 C1orf52 0.82 8.5 0.42 6.01e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7552404 1.000 rs7548962 chr1:76139266 G/A cg03433033 chr1:76189801 ACADM 0.67 9.65 0.46 1.24e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2549003 1.000 rs10068129 chr5:131821246 A/G cg02551604 chr5:131831745 NA 0.43 6.59 0.34 1.69e-10 Asthma (sex interaction); LIHC cis rs17401966 0.838 rs2105212 chr1:10281012 T/C cg19773385 chr1:10388646 KIF1B -0.37 -6.79 -0.34 4.95e-11 Hepatocellular carcinoma; LIHC cis rs3862260 0.509 rs2281493 chr1:120162787 T/C cg16322792 chr1:120165303 ZNF697 0.53 9.71 0.47 7.38e-20 Systemic lupus erythematosus; LIHC cis rs9399135 0.933 rs41294852 chr6:135376379 T/G cg24558204 chr6:135376177 HBS1L 0.43 7.09 0.36 7.64e-12 Red blood cell count; LIHC cis rs7312933 1.000 rs7312933 chr12:42503467 C/T cg01256987 chr12:42539512 GXYLT1 0.4 6.8 0.34 4.8e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs919433 0.680 rs788021 chr2:198293691 T/C cg10820045 chr2:198174542 NA 0.56 9.02 0.44 1.35e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg27286337 chr10:134555280 INPP5A 0.94 13.39 0.59 3.54e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg05368731 chr17:41323189 NBR1 0.73 12.6 0.56 3.78e-30 Menopause (age at onset); LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.72 10.57 0.5 8.58e-23 Lymphocyte counts; LIHC cis rs11758351 0.660 rs11757754 chr6:26219744 A/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs738322 0.967 rs4385 chr22:38573229 T/C cg25457927 chr22:38595422 NA -0.27 -6.62 -0.34 1.41e-10 Cutaneous nevi; LIHC cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg16434002 chr17:42200994 HDAC5 0.5 7.26 0.37 2.64e-12 Total body bone mineral density; LIHC cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg03517284 chr6:25882590 NA -0.82 -12.18 -0.55 1.3e-28 Blood metabolite levels; LIHC cis rs4332037 0.539 rs11764590 chr7:2032803 C/T cg23422044 chr7:1970798 MAD1L1 -0.62 -7.0 -0.35 1.35e-11 Bipolar disorder; LIHC cis rs2404602 0.692 rs12902452 chr15:76921465 T/C cg03037974 chr15:76606532 NA 0.74 14.39 0.61 4.85e-37 Blood metabolite levels; LIHC cis rs17739167 0.550 rs11634233 chr15:42224563 G/A cg20935245 chr15:42234343 EHD4 0.4 7.34 0.37 1.62e-12 Monocyte count; LIHC cis rs644799 0.544 rs1622515 chr11:95523433 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.68 11.1 0.51 1.13e-24 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg24209194 chr3:40518798 ZNF619 0.63 9.73 0.47 6.66e-20 Renal cell carcinoma; LIHC cis rs4713118 0.621 rs9295755 chr6:28033174 C/T cg16479474 chr6:28041457 NA -0.45 -6.68 -0.34 9.49e-11 Parkinson's disease; LIHC cis rs79149102 0.579 rs7163390 chr15:75280426 T/C cg09165964 chr15:75287851 SCAMP5 -0.57 -7.76 -0.39 9.98e-14 Lung cancer; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg27432699 chr2:27873401 GPN1 -0.52 -7.38 -0.37 1.19e-12 Total body bone mineral density; LIHC cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7408868 0.908 rs62113793 chr19:15277336 G/A cg09752223 chr19:15281200 NOTCH3 -0.37 -5.83 -0.3 1.28e-8 Pulse pressure; LIHC cis rs11663156 1.000 rs1010360 chr18:50928441 A/C cg24270629 chr18:50823537 DCC -0.49 -6.76 -0.34 6.02e-11 Intelligence (multi-trait analysis); LIHC cis rs3008870 1.000 rs2755244 chr1:67484470 C/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.79 -0.3 1.63e-8 Lymphocyte percentage of white cells; LIHC cis rs17685 0.816 rs11763076 chr7:75765963 C/T cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8067354 0.831 rs2333617 chr17:57896220 T/A cg02344993 chr17:57696989 CLTC -0.57 -9.29 -0.45 1.78e-18 Hemoglobin concentration; LIHC trans rs2243480 0.711 rs2460426 chr7:65623129 A/G cg10756647 chr7:56101905 PSPH -1.1 -13.4 -0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs17384381 1.000 rs12743049 chr1:85897386 G/A cg16011679 chr1:85725395 C1orf52 0.79 8.38 0.41 1.42e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs4474465 0.688 rs7927494 chr11:78280578 G/A cg27205649 chr11:78285834 NARS2 0.49 7.6 0.38 2.95e-13 Alzheimer's disease (survival time); LIHC cis rs7592578 0.766 rs12472081 chr2:191398545 G/A cg27211696 chr2:191398769 TMEM194B -0.69 -8.91 -0.43 3.16e-17 Diastolic blood pressure; LIHC cis rs4076764 0.515 rs4657268 chr1:163376507 A/T cg24596788 chr1:163392923 NA -0.21 -6.59 -0.34 1.69e-10 Motion sickness; LIHC cis rs986417 0.818 rs12880313 chr14:60935504 T/C cg27398547 chr14:60952738 C14orf39 0.77 8.77 0.43 8.38e-17 Gut microbiota (bacterial taxa); LIHC cis rs3806843 0.966 rs3756341 chr5:140171194 C/T cg26395211 chr5:140044315 WDR55 -0.43 -6.43 -0.33 4.19e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6964587 1.000 rs13231578 chr7:91663266 C/T cg17063962 chr7:91808500 NA 0.99 18.54 0.71 1.32e-53 Breast cancer; LIHC trans rs12752401 0.717 rs34542611 chr1:103028047 C/T cg24921808 chr19:740313 PALM 0.48 6.31 0.32 8.9e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg18252515 chr7:66147081 NA -1.27 -16.34 -0.66 9.2e-45 Diabetic kidney disease; LIHC cis rs9303280 0.836 rs12453507 chr17:38053207 C/G cg11212589 chr17:38028394 ZPBP2 0.39 8.09 0.4 1.03e-14 Self-reported allergy; LIHC cis rs4631830 0.720 rs12763717 chr10:51500874 C/G cg16070123 chr10:51489643 NA 0.38 5.92 0.3 7.8e-9 Prostate-specific antigen levels; LIHC cis rs7572733 0.555 rs7600269 chr2:198923468 C/G cg10820045 chr2:198174542 NA 0.42 6.13 0.31 2.43e-9 Dermatomyositis; LIHC cis rs8141529 0.748 rs1318026 chr22:29283518 A/G cg02153584 chr22:29168773 CCDC117 0.52 8.12 0.4 8.73e-15 Lymphocyte counts; LIHC cis rs12702595 0.509 rs2159191 chr7:7266939 A/G cg04827551 chr7:7268805 C1GALT1 0.33 6.18 0.32 1.84e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg15382696 chr6:118971807 C6orf204 0.64 6.24 0.32 1.28e-9 Diastolic blood pressure; LIHC cis rs9291683 0.609 rs55959894 chr4:10026580 G/A cg11266682 chr4:10021025 SLC2A9 0.34 7.34 0.37 1.59e-12 Bone mineral density; LIHC cis rs7086627 0.515 rs11202957 chr10:82209592 A/G cg01528321 chr10:82214614 TSPAN14 0.52 7.42 0.37 9.28e-13 Post bronchodilator FEV1; LIHC cis rs8053891 0.615 rs2287997 chr16:72140553 G/A cg16558253 chr16:72132732 DHX38 -0.45 -6.04 -0.31 4.01e-9 Coronary artery disease; LIHC cis rs916888 0.773 rs199439 chr17:44793503 A/G cg15921436 chr17:44337874 NA 0.65 6.61 0.34 1.47e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4713118 0.513 rs156738 chr6:28014025 G/C cg23485639 chr6:28045615 ZNF165 0.38 5.87 0.3 1.03e-8 Parkinson's disease; LIHC cis rs12497850 0.797 rs61583136 chr3:49189195 C/T cg06212747 chr3:49208901 KLHDC8B 0.6 7.93 0.39 3.18e-14 Parkinson's disease; LIHC cis rs12984174 1.000 rs403439 chr19:18142075 A/G cg21649277 chr19:18117794 ARRDC2 -0.68 -6.58 -0.34 1.75e-10 Pulmonary function in asthmatics; LIHC cis rs8114671 0.804 rs6060139 chr20:33566499 T/C cg07148914 chr20:33460835 GGT7 0.56 8.59 0.42 3.08e-16 Height; LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.65 -6.96 -0.35 1.7e-11 Diastolic blood pressure; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg20887711 chr4:1340912 KIAA1530 0.82 12.99 0.57 1.22e-31 Longevity; LIHC cis rs3748682 0.821 rs12751325 chr1:38289383 T/C cg12658694 chr1:38397304 INPP5B 0.43 5.92 0.3 7.76e-9 Hypothyroidism; LIHC cis rs4820294 0.926 rs62236671 chr22:38069305 G/A cg00292662 chr22:38071168 LGALS1 0.64 10.16 0.48 2.34e-21 Fat distribution (HIV); LIHC cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg08219700 chr8:58056026 NA 0.44 5.72 0.3 2.27e-8 Developmental language disorder (linguistic errors); LIHC cis rs910316 0.967 rs11624893 chr14:75660124 A/G cg08847533 chr14:75593920 NEK9 -0.81 -16.32 -0.66 1.06e-44 Height; LIHC cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg11890956 chr21:40555474 PSMG1 1.02 13.88 0.6 4.91e-35 Cognitive function; LIHC cis rs2180341 0.960 rs7753913 chr6:127671296 A/G cg24812749 chr6:127587940 RNF146 1.05 15.38 0.64 6.23e-41 Breast cancer; LIHC cis rs9368481 0.761 rs6918835 chr6:27017827 T/G cg12292205 chr6:26970375 C6orf41 -0.46 -7.78 -0.39 8.54e-14 Autism spectrum disorder or schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02073427 chr10:15252052 NA 0.46 7.01 0.35 1.28e-11 Pancreatic cancer; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC trans rs208520 1.000 rs12190316 chr6:66973365 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.7 0.34 8.37e-11 Exhaled nitric oxide output; LIHC cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg02353165 chr6:42928485 GNMT 0.76 11.97 0.54 8.4e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2404602 0.716 rs17461634 chr15:76764107 G/A cg23625390 chr15:77176239 SCAPER 0.37 6.1 0.31 2.83e-9 Blood metabolite levels; LIHC cis rs921968 0.643 rs2278530 chr2:219501133 G/A cg18887096 chr2:219472410 PLCD4 0.34 5.77 0.3 1.74e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs6782228 0.675 rs4443194 chr3:128383446 T/A cg16766828 chr3:128327626 NA -0.43 -6.8 -0.35 4.66e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg09455208 chr3:40491958 NA -0.36 -7.38 -0.37 1.22e-12 Renal cell carcinoma; LIHC cis rs7208859 0.623 rs2035494 chr17:29130393 T/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1051424 0.642 rs115869798 chr17:57892829 T/A cg13753209 chr17:57696993 CLTC 0.74 11.66 0.53 1.11e-26 Obesity-related traits; LIHC cis rs13191362 1.000 rs71567659 chr6:163001736 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs763121 0.849 rs12004 chr22:38877461 T/G cg06022373 chr22:39101656 GTPBP1 0.62 10.42 0.49 2.82e-22 Menopause (age at onset); LIHC cis rs11229555 0.645 rs7116847 chr11:58178478 C/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs8103278 1.000 rs8108864 chr19:46301671 G/A cg14061069 chr19:46274453 DMPK -0.55 -8.58 -0.42 3.39e-16 Coronary artery disease; LIHC cis rs11608355 0.515 rs4766605 chr12:109895636 C/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs7100689 0.784 rs1972370 chr10:82127180 A/G cg00277334 chr10:82204260 NA -0.54 -6.68 -0.34 9.51e-11 Post bronchodilator FEV1; LIHC cis rs6701037 1.000 rs6681020 chr1:175125264 G/A cg17845761 chr1:175162550 KIAA0040 -0.35 -5.74 -0.3 2.11e-8 Alcohol dependence; LIHC cis rs17776563 0.959 rs13329353 chr15:89113877 A/G cg05013243 chr15:89149849 MIR1179 0.46 7.68 0.38 1.69e-13 Thyroid hormone levels; LIHC cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg16049864 chr8:95962084 TP53INP1 -0.6 -11.49 -0.53 4.52e-26 Type 2 diabetes; LIHC cis rs9303401 0.614 rs34058624 chr17:57118121 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.85 0.54 2.26e-27 Cognitive test performance; LIHC cis rs11077998 0.935 rs11653926 chr17:80484953 G/A cg10255544 chr17:80519551 FOXK2 0.48 8.71 0.43 1.34e-16 Reticulocyte fraction of red cells; LIHC cis rs9993613 1.000 rs7697556 chr4:73515313 C/T cg15102770 chr4:73434591 ADAMTS3 0.38 6.06 0.31 3.69e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs17106184 1.000 rs12085022 chr1:51269018 T/C cg07174182 chr1:51127561 FAF1 -0.64 -7.03 -0.36 1.09e-11 Type 2 diabetes; LIHC cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg14004847 chr7:1930337 MAD1L1 -0.5 -7.18 -0.36 4.4e-12 Bipolar disorder and schizophrenia; LIHC cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg23978390 chr7:1156363 C7orf50 0.47 7.19 0.36 4.18e-12 Longevity;Endometriosis; LIHC cis rs9911578 0.933 rs74370218 chr17:57095212 C/T cg05425664 chr17:57184151 TRIM37 0.6 8.99 0.44 1.67e-17 Intelligence (multi-trait analysis); LIHC cis rs8141529 0.702 rs469991 chr22:29307859 G/C cg15103426 chr22:29168792 CCDC117 -0.57 -9.27 -0.45 2.21e-18 Lymphocyte counts; LIHC cis rs694739 0.628 rs645078 chr11:64135298 A/C cg02228329 chr11:64053129 BAD;GPR137 0.57 7.89 0.39 4.06e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs611744 0.658 rs2443774 chr8:109064957 T/C cg21045802 chr8:109455806 TTC35 0.43 7.22 0.36 3.4e-12 Dupuytren's disease; LIHC cis rs911119 0.913 rs6048923 chr20:23578206 C/T cg16589663 chr20:23618590 CST3 0.73 7.41 0.37 1.03e-12 Chronic kidney disease; LIHC cis rs1593 0.565 rs10025152 chr4:187225304 C/T cg14349977 chr4:187219430 NA 0.42 6.8 0.35 4.67e-11 Activated partial thromboplastin time; LIHC cis rs7772486 0.720 rs9403757 chr6:146261271 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -5.86 -0.3 1.07e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2952156 0.876 rs903504 chr17:37829570 C/G cg00129232 chr17:37814104 STARD3 -0.54 -10.07 -0.48 4.6e-21 Asthma; LIHC cis rs10129255 0.576 rs2157616 chr14:107176045 T/C cg07958169 chr14:107095056 NA -0.33 -5.71 -0.3 2.43e-8 Kawasaki disease; LIHC cis rs933688 1.000 rs6866191 chr5:90746852 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.97 19.54 0.73 1.28e-57 Smoking behavior; LIHC cis rs7238033 0.663 rs11082468 chr18:43321028 A/G cg20610511 chr18:43302872 SLC14A1 0.37 6.15 0.32 2.17e-9 Bladder cancer; LIHC trans rs10411161 0.702 rs7247017 chr19:52391769 T/C cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs34779708 0.966 rs35146199 chr10:35460939 T/C cg03585969 chr10:35415529 CREM 0.87 13.09 0.58 4.92e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3213545 0.700 rs2260399 chr12:121469653 C/T cg15155738 chr12:121454335 C12orf43 0.45 6.54 0.33 2.27e-10 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs10464366 0.544 rs1525799 chr7:39153131 C/G cg20302533 chr7:39170763 POU6F2 -0.37 -6.75 -0.34 6.34e-11 IgG glycosylation; LIHC cis rs17152411 1.000 rs17152374 chr10:126592644 T/C cg07906193 chr10:126599966 NA 0.46 6.94 0.35 1.99e-11 Height; LIHC trans rs4865875 0.792 rs6891667 chr5:54139679 C/T cg04079215 chr1:95095221 NA -0.41 -6.07 -0.31 3.43e-9 Sense of smell; LIHC trans rs10411161 0.702 rs7251689 chr19:52389117 A/T cg22319618 chr22:45562946 NUP50 -0.62 -8.49 -0.42 6.32e-16 Breast cancer; LIHC cis rs4684776 0.935 rs11713733 chr3:11400552 G/A cg00170343 chr3:11313890 ATG7 -0.46 -6.27 -0.32 1.06e-9 Small vessel stroke; LIHC cis rs8027181 1.000 rs3850986 chr15:73091283 G/T cg25632853 chr15:73088954 NA 0.37 6.17 0.32 1.93e-9 Triglyceride levels; LIHC cis rs7927592 0.913 rs67605986 chr11:68300955 C/T cg16797656 chr11:68205561 LRP5 0.51 8.1 0.4 9.54e-15 Total body bone mineral density; LIHC cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg11890956 chr21:40555474 PSMG1 -0.46 -7.61 -0.38 2.72e-13 Cognitive function; LIHC cis rs2933343 0.700 rs1683779 chr3:128642048 A/G cg24203234 chr3:128598194 ACAD9 0.46 6.43 0.33 4.19e-10 IgG glycosylation; LIHC cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg12310025 chr6:25882481 NA 0.6 8.16 0.4 6.29e-15 Blood metabolite levels; LIHC cis rs6430585 0.528 rs309113 chr2:136737460 C/A cg07169764 chr2:136633963 MCM6 0.95 14.54 0.62 1.28e-37 Corneal structure; LIHC cis rs651907 0.535 rs11707250 chr3:101509371 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.67 -10.97 -0.51 3.32e-24 Colorectal cancer; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg26338869 chr17:61819248 STRADA 0.61 8.9 0.43 3.37e-17 Prudent dietary pattern; LIHC cis rs72627509 0.904 rs17081933 chr4:57822869 T/A cg26694713 chr4:57773883 REST 0.7 9.68 0.46 9.36e-20 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2180341 0.889 rs9321074 chr6:127618019 G/A cg24812749 chr6:127587940 RNF146 1.07 16.08 0.66 9.77e-44 Breast cancer; LIHC cis rs651907 0.557 rs11712748 chr3:101383562 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.47 -6.75 -0.34 6.39e-11 Colorectal cancer; LIHC cis rs2576037 0.583 rs1970668 chr18:44523220 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.72 11.19 0.52 5.7e-25 Personality dimensions; LIHC cis rs916888 0.821 rs199513 chr17:44856932 A/G cg01570182 chr17:44337453 NA -0.89 -9.17 -0.44 4.48e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs79149102 0.579 rs3910748 chr15:75318652 A/G cg15902774 chr15:75289873 SCAMP5 0.43 6.56 0.33 2.04e-10 Lung cancer; LIHC cis rs1691799 0.899 rs1168299 chr12:66736074 C/G cg16791601 chr12:66731901 HELB -0.57 -13.94 -0.6 2.75e-35 White blood cell count (basophil); LIHC cis rs7131987 0.621 rs3782506 chr12:29445422 A/C cg21522988 chr12:29376872 FAR2 -0.26 -5.91 -0.3 8.23e-9 QT interval; LIHC cis rs2997447 0.846 rs3008417 chr1:26403470 G/A cg19633962 chr1:26362018 EXTL1 -0.53 -6.05 -0.31 3.79e-9 QRS complex (12-leadsum); LIHC cis rs7602441 0.521 rs74742552 chr2:14773375 G/T cg06545361 chr2:14773388 FAM84A 0.52 5.84 0.3 1.22e-8 Visceral adipose tissue adjusted for BMI; LIHC cis rs6089584 0.566 rs6061972 chr20:60610245 C/T cg23262073 chr20:60523788 NA -0.28 -5.95 -0.31 6.51e-9 Body mass index; LIHC cis rs6912958 0.712 rs4706294 chr6:88317675 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.93 -0.39 3.15e-14 Monocyte percentage of white cells; LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg00656387 chr3:40428638 ENTPD3 -0.51 -8.72 -0.43 1.24e-16 Renal cell carcinoma; LIHC cis rs10870270 0.912 rs7079991 chr10:133736130 A/G cg08754478 chr10:133766260 PPP2R2D -0.56 -8.27 -0.41 3.08e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7542091 0.813 rs2049999 chr1:210031331 A/G cg22029157 chr1:209979665 IRF6 0.37 6.08 0.31 3.3e-9 Monobrow; LIHC cis rs25645 0.502 rs17609240 chr17:38110689 T/G cg17467752 chr17:38218738 THRA 0.4 5.85 0.3 1.12e-8 Myeloid white cell count; LIHC cis rs2292864 0.764 rs36046953 chr17:45381791 A/G cg18085866 chr17:45331354 ITGB3 -0.64 -6.68 -0.34 9.87e-11 Left atrial antero-posterior diameter; LIHC cis rs9814567 1.000 rs1534025 chr3:134313304 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.22 0.32 1.49e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs17685 0.712 rs2158867 chr7:75815141 C/A cg19862616 chr7:65841803 NCRNA00174 0.89 18.14 0.7 5.21e-52 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg24431193 chr11:63883947 FLRT1;MACROD1 -0.36 -5.72 -0.3 2.32e-8 Platelet count; LIHC cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg02290350 chr8:58132656 NA 0.41 8.59 0.42 3.16e-16 Developmental language disorder (linguistic errors); LIHC cis rs11252926 0.527 rs11252754 chr10:538637 G/A cg09445902 chr10:555545 DIP2C -0.39 -6.3 -0.32 9.15e-10 Psychosis in Alzheimer's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg02995680 chr14:103430766 CDC42BPB 0.47 7.11 0.36 6.86e-12 Longevity; LIHC cis rs11190604 0.767 rs10883491 chr10:102196071 G/T cg07080220 chr10:102295463 HIF1AN 0.48 6.94 0.35 1.96e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg23131131 chr22:24373011 LOC391322 -0.6 -8.46 -0.42 8.01e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2549003 0.966 rs2070730 chr5:131819800 G/A cg02551604 chr5:131831745 NA -0.44 -6.54 -0.33 2.24e-10 Asthma (sex interaction); LIHC cis rs8141529 0.551 rs16986864 chr22:29350911 G/T cg15103426 chr22:29168792 CCDC117 0.44 6.15 0.32 2.14e-9 Lymphocyte counts; LIHC trans rs2243480 1.000 rs316334 chr7:65602126 G/T cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs1552244 0.882 rs13063929 chr3:10010308 T/C cg00149659 chr3:10157352 C3orf10 0.53 6.1 0.31 2.93e-9 Alzheimer's disease; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg16318947 chr17:78355466 RNF213;LOC100294362 0.44 6.58 0.34 1.78e-10 Alopecia areata; LIHC cis rs9513627 1.000 rs2147625 chr13:100140645 G/T cg25919922 chr13:100150906 NA 0.79 7.14 0.36 5.57e-12 Obesity-related traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19355919 chr18:48346593 MRO -0.46 -6.09 -0.31 3.1e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9658691 0.607 rs12411483 chr10:90780910 G/T cg03111039 chr10:90751583 FAS;ACTA2 -0.93 -6.71 -0.34 8.01e-11 Mosquito bite size; LIHC cis rs7918232 0.941 rs1755399 chr10:27394958 A/G cg14240646 chr10:27532245 ACBD5 -0.69 -6.41 -0.33 4.77e-10 Breast cancer; LIHC cis rs11105298 0.891 rs10858864 chr12:89846230 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.37 -0.37 1.25e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs17017235 0.649 rs6845910 chr4:91481236 A/C cg17163168 chr1:3600735 TP73 -0.58 -6.08 -0.31 3.15e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6665290 0.669 rs3768424 chr1:227177444 A/G cg10327440 chr1:227177885 CDC42BPA -1.14 -28.17 -0.84 3.99e-91 Myeloid white cell count; LIHC cis rs240764 0.680 rs239234 chr6:101101234 G/A cg09795085 chr6:101329169 ASCC3 0.46 6.66 0.34 1.08e-10 Neuroticism; LIHC cis rs4474465 0.920 rs7113559 chr11:78205703 T/G cg27205649 chr11:78285834 NARS2 0.4 6.2 0.32 1.6e-9 Alzheimer's disease (survival time); LIHC cis rs2439831 0.702 rs16977724 chr15:44151299 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.58 7.13 0.36 6.07e-12 Lung cancer in ever smokers; LIHC cis rs7219014 1 rs7219014 chr17:37624790 A/G cg00129232 chr17:37814104 STARD3 -0.42 -6.81 -0.35 4.53e-11 Urinary metabolites; LIHC cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg26116260 chr4:7069785 GRPEL1 1.0 18.45 0.71 2.99e-53 Monocyte percentage of white cells; LIHC cis rs80282103 0.764 rs12247779 chr10:1107957 T/G cg18964960 chr10:1102726 WDR37 0.65 5.86 0.3 1.1e-8 Glomerular filtration rate (creatinine); LIHC cis rs9303401 0.659 rs62081315 chr17:56781468 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs507080 0.922 rs514143 chr11:118558449 G/A cg04173919 chr11:118528438 PHLDB1 0.35 6.6 0.34 1.56e-10 Serum metabolite levels; LIHC cis rs6667605 0.527 rs4422947 chr1:2539590 C/T cg18854424 chr1:2615690 NA 0.33 7.38 0.37 1.19e-12 Inflammatory bowel disease;Ulcerative colitis; LIHC trans rs7618501 1.000 rs9859153 chr3:49807085 G/T cg21659725 chr3:3221576 CRBN 0.99 19.71 0.73 2.65e-58 Intelligence (multi-trait analysis); LIHC cis rs12079745 0.793 rs12081030 chr1:169350003 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 2.01e-11 QT interval; LIHC cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.11 -15.52 -0.64 1.77e-41 Gut microbiome composition (summer); LIHC cis rs8180040 0.966 rs11705957 chr3:47443262 T/G cg16586182 chr3:47516702 SCAP 0.6 11.59 0.53 2.08e-26 Colorectal cancer; LIHC cis rs919433 0.680 rs12621129 chr2:198265350 T/C cg10820045 chr2:198174542 NA -0.55 -8.82 -0.43 5.83e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg06481639 chr22:41940642 POLR3H 0.71 7.06 0.36 9.26e-12 Vitiligo; LIHC cis rs6088590 0.930 rs6120723 chr20:33364655 C/T cg06115741 chr20:33292138 TP53INP2 0.59 8.18 0.4 5.81e-15 Coronary artery disease; LIHC cis rs780096 0.587 rs10205219 chr2:27568565 T/C cg05484376 chr2:27715224 FNDC4 0.34 5.75 0.3 2.03e-8 Total body bone mineral density; LIHC cis rs9640161 0.636 rs3735171 chr7:150033882 A/G cg10018233 chr7:150070692 REPIN1 0.56 8.62 0.42 2.44e-16 Blood protein levels;Circulating chemerin levels; LIHC trans rs2727020 0.729 rs1917325 chr11:49370004 G/A cg18944383 chr4:111397179 ENPEP 0.26 6.31 0.32 8.62e-10 Coronary artery disease; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.03 0.36 1.1e-11 Renal cell carcinoma; LIHC cis rs7729447 0.804 rs4867471 chr5:32693456 A/T cg16267343 chr5:32710456 NPR3 0.47 5.78 0.3 1.71e-8 Blood pressure; LIHC cis rs253664 0.898 rs1624314 chr3:138084976 T/C cg25188949 chr3:137893707 DBR1 -0.56 -5.72 -0.3 2.36e-8 Body mass index; LIHC cis rs769267 0.965 rs2074299 chr19:19380646 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.01 0.31 4.74e-9 Tonsillectomy; LIHC cis rs1005277 0.522 rs1208767 chr10:38042295 G/T cg00409905 chr10:38381863 ZNF37A -0.56 -9.61 -0.46 1.63e-19 Extrinsic epigenetic age acceleration; LIHC cis rs7618501 1.000 rs6446295 chr3:49809063 G/T cg21467203 chr3:49911342 NA -0.41 -7.09 -0.36 7.66e-12 Intelligence (multi-trait analysis); LIHC cis rs17270561 0.609 rs9467572 chr6:25704126 T/G cg17691542 chr6:26056736 HIST1H1C -0.44 -5.99 -0.31 5.44e-9 Iron status biomarkers; LIHC cis rs3762637 1.000 rs10934602 chr3:122223182 A/C cg24169773 chr3:122142474 KPNA1 0.45 8.91 0.43 2.98e-17 LDL cholesterol levels; LIHC cis rs12144094 0.882 rs1441011 chr1:120245374 T/C cg20995928 chr1:120229863 NA 0.42 7.23 0.36 3.14e-12 Height; LIHC cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg19729930 chr2:74357872 NA 0.66 12.96 0.57 1.6e-31 Gestational age at birth (maternal effect); LIHC cis rs9916302 0.706 rs12937013 chr17:37665571 G/A cg07936489 chr17:37558343 FBXL20 -0.84 -12.09 -0.55 2.86e-28 Glomerular filtration rate (creatinine); LIHC trans rs7246657 0.943 rs7259968 chr19:37811854 T/C cg10208301 chr11:6592745 DNHD1 0.47 6.75 0.34 6.31e-11 Coronary artery calcification; LIHC cis rs6964587 0.934 rs2961019 chr7:91572749 T/G cg17063962 chr7:91808500 NA -0.99 -15.84 -0.65 9.03e-43 Breast cancer; LIHC cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs6782228 0.527 rs2712371 chr3:128346214 G/A cg16766828 chr3:128327626 NA -0.41 -6.51 -0.33 2.69e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs77633900 0.614 rs2629021 chr15:76974083 C/T cg21673338 chr15:77095150 SCAPER -0.49 -7.52 -0.38 4.89e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs6690583 0.623 rs2083284 chr1:85440023 C/T cg22153463 chr1:85462885 MCOLN2 0.52 6.17 0.32 1.93e-9 Serum sulfate level; LIHC cis rs10489202 0.632 rs12401555 chr1:168069473 G/C cg24449463 chr1:168025552 DCAF6 -0.51 -6.87 -0.35 2.99e-11 Schizophrenia; LIHC cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg18230493 chr5:56204884 C5orf35 -0.45 -6.22 -0.32 1.47e-9 Initial pursuit acceleration; LIHC cis rs9640161 0.789 rs28439010 chr7:150046276 C/T cg27494647 chr7:150038898 RARRES2 0.36 6.81 0.35 4.4e-11 Blood protein levels;Circulating chemerin levels; LIHC cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg00166722 chr3:10149974 C3orf24 0.46 5.8 0.3 1.53e-8 Alzheimer's disease; LIHC cis rs875971 0.830 rs6976714 chr7:65891461 G/A cg18876405 chr7:65276391 NA 0.37 6.68 0.34 9.57e-11 Aortic root size; LIHC cis rs763121 0.925 rs9611008 chr22:39098787 T/C cg06022373 chr22:39101656 GTPBP1 0.7 13.9 0.6 4.06e-35 Menopause (age at onset); LIHC cis rs6434928 1 rs6434928 chr2:198304577 G/A cg10820045 chr2:198174542 NA 0.56 9.02 0.44 1.35e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg18252515 chr7:66147081 NA -1.24 -15.89 -0.65 5.57e-43 Diabetic kidney disease; LIHC cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg23758822 chr17:41437982 NA 0.95 17.63 0.69 5.92e-50 Menopause (age at onset); LIHC cis rs10883723 0.810 rs10748824 chr10:104274466 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs2197308 0.765 rs11182900 chr12:37934009 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs4975709 0.569 rs931509 chr5:1858821 A/T cg14773178 chr5:1868261 NA 0.26 6.67 0.34 1.01e-10 Cardiovascular disease risk factors; LIHC cis rs17102884 0.506 rs11845397 chr14:75404587 G/A cg08847533 chr14:75593920 NEK9 -0.61 -10.86 -0.51 8.27e-24 Neuroticism; LIHC cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg05552183 chr6:42928497 GNMT 0.68 10.19 0.48 1.85e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs5758511 0.680 rs34107327 chr22:42648353 T/G cg20195005 chr22:42527684 CYP2D6 0.31 5.88 0.3 9.93e-9 Birth weight; LIHC cis rs6754311 0.597 rs6760329 chr2:136544752 A/G cg15123519 chr2:136567270 LCT 0.35 6.72 0.34 7.75e-11 Mosquito bite size; LIHC cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg12463550 chr7:65579703 CRCP 0.67 7.06 0.36 9.27e-12 Diabetic kidney disease; LIHC trans rs8073060 0.586 rs6505484 chr17:33993152 G/A cg19694781 chr19:47549865 TMEM160 -1.28 -13.83 -0.6 7.33e-35 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7512552 0.839 rs11590787 chr1:150398531 G/A cg15654264 chr1:150340011 RPRD2 0.69 11.23 0.52 4.11e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2073300 0.609 rs6137938 chr20:23389127 C/G cg12062639 chr20:23401060 NAPB 1.07 14.42 0.61 3.64e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2549003 1.000 rs7735073 chr5:131815357 G/A cg21138405 chr5:131827807 IRF1 0.37 9.6 0.46 1.71e-19 Asthma (sex interaction); LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg10774155 chr7:65338427 VKORC1L1 -0.44 -6.58 -0.34 1.78e-10 Calcium levels; LIHC cis rs4803468 1.000 rs2241706 chr19:41912807 A/G cg14132834 chr19:41945861 ATP5SL -0.43 -6.34 -0.32 7.13e-10 Height; LIHC cis rs3806843 1.000 rs11167600 chr5:140174865 G/C cg19875535 chr5:140030758 IK 0.37 5.96 0.31 6.29e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4970988 0.501 rs11204713 chr1:150694623 T/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Urate levels; LIHC cis rs2070488 0.965 rs13079145 chr3:38517992 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.01 0.65 1.98e-43 Electrocardiographic conduction measures; LIHC cis rs7769051 0.614 rs6912936 chr6:133102664 A/G cg22852734 chr6:133119734 C6orf192 0.94 9.28 0.45 1.95e-18 Type 2 diabetes nephropathy; LIHC cis rs11758351 0.660 rs77130538 chr6:26210723 T/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.43 0.33 4.36e-10 Gout;Renal underexcretion gout; LIHC cis rs4332037 0.707 rs4721096 chr7:1877311 T/C cg23422044 chr7:1970798 MAD1L1 0.59 6.95 0.35 1.86e-11 Bipolar disorder; LIHC cis rs9901225 1 rs9901225 chr17:40755811 C/T cg03582285 chr17:40700314 NA -0.41 -7.06 -0.36 9.18e-12 Colorectal or endometrial cancer; LIHC cis rs9916302 0.851 rs6503518 chr17:37660469 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.34 -0.59 5.58e-33 Glomerular filtration rate (creatinine); LIHC cis rs7829975 0.623 rs10087493 chr8:8373557 A/G cg15556689 chr8:8085844 FLJ10661 -0.37 -5.8 -0.3 1.5e-8 Mood instability; LIHC cis rs7927771 0.524 rs10838760 chr11:47786414 A/G cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg23982607 chr1:1823379 GNB1 -0.75 -15.55 -0.64 1.24e-41 Body mass index; LIHC cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.12 11.22 0.52 4.26e-25 Platelet count; LIHC cis rs4144743 0.702 rs16941733 chr17:45318289 T/C cg18085866 chr17:45331354 ITGB3 -0.64 -7.51 -0.38 5.05e-13 Body mass index; LIHC cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg07424592 chr7:64974309 NA 0.8 9.08 0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.47 0.33 3.39e-10 Mean platelet volume; LIHC cis rs5769765 0.908 rs9627788 chr22:50300438 T/C cg26441486 chr22:50317300 CRELD2 0.34 6.08 0.31 3.14e-9 Schizophrenia; LIHC cis rs28595532 0.748 rs113336496 chr4:119336957 C/T cg21605333 chr4:119757512 SEC24D 0.97 8.11 0.4 9.41e-15 Cannabis dependence symptom count; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.73 -0.3 2.25e-8 Total body bone mineral density; LIHC cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg11764359 chr7:65958608 NA -0.58 -6.04 -0.31 3.97e-9 Diabetic kidney disease; LIHC cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg06238570 chr21:40685208 BRWD1 0.6 7.3 0.37 1.98e-12 Cognitive function; LIHC cis rs8103278 0.507 rs3745802 chr19:46271177 G/T cg02376097 chr19:46275166 DMPK 0.51 8.98 0.44 1.9e-17 Coronary artery disease; LIHC cis rs780096 0.565 rs13022659 chr2:27743630 C/T cg27432699 chr2:27873401 GPN1 -0.6 -8.65 -0.42 1.99e-16 Total body bone mineral density; LIHC cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg17971929 chr21:40555470 PSMG1 0.86 10.34 0.49 5.57e-22 Cognitive function; LIHC cis rs12464559 0.522 rs6715027 chr2:152626657 T/C cg01189475 chr2:152685088 ARL5A 0.66 8.12 0.4 8.31e-15 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs1865760 1.000 rs9358893 chr6:25921761 A/G cg17691542 chr6:26056736 HIST1H1C 0.42 6.27 0.32 1.06e-9 Height; LIHC cis rs12200782 0.505 rs7765920 chr6:26514771 C/T cg09904177 chr6:26538194 HMGN4 0.49 6.81 0.35 4.39e-11 Small cell lung carcinoma; LIHC cis rs7927771 0.931 rs4752801 chr11:47907641 A/G cg20307385 chr11:47447363 PSMC3 -0.48 -6.37 -0.33 6.15e-10 Subjective well-being; LIHC cis rs2839186 0.560 rs9975345 chr21:47843004 T/C cg05896524 chr21:47604654 C21orf56 -0.4 -6.34 -0.32 7.18e-10 Testicular germ cell tumor; LIHC cis rs1552244 0.572 rs67227131 chr3:10172744 G/A cg00149659 chr3:10157352 C3orf10 1.13 9.34 0.45 1.31e-18 Alzheimer's disease; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg11644478 chr21:40555479 PSMG1 0.79 9.9 0.47 1.7e-20 Cognitive function; LIHC cis rs311392 0.902 rs423150 chr8:55092804 C/T cg20636351 chr8:55087400 NA -0.38 -7.71 -0.38 1.41e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs4665809 0.680 rs3955310 chr2:26290828 T/G cg04944784 chr2:26401820 FAM59B -0.65 -8.26 -0.41 3.22e-15 Gut microbiome composition (summer); LIHC cis rs2576037 0.526 rs10853545 chr18:44475220 A/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.5 -7.36 -0.37 1.36e-12 Personality dimensions; LIHC cis rs9640161 0.617 rs56019796 chr7:150009226 T/C cg27494647 chr7:150038898 RARRES2 0.3 5.79 0.3 1.63e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs4934494 0.911 rs34486602 chr10:91415652 T/C cg19698084 chr10:91461284 KIF20B -0.45 -6.18 -0.32 1.85e-9 Red blood cell count; LIHC cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg17971929 chr21:40555470 PSMG1 0.85 10.27 0.49 9.85e-22 Cognitive function; LIHC cis rs7264396 0.790 rs10211771 chr20:34219994 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.71 -11.77 -0.54 4.44e-27 Total cholesterol levels; LIHC cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg18876405 chr7:65276391 NA -0.55 -9.16 -0.44 4.79e-18 Aortic root size; LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs11958404 0.615 rs7737601 chr5:157448269 C/T cg05962755 chr5:157440814 NA -0.61 -8.12 -0.4 8.43e-15 IgG glycosylation; LIHC cis rs10876993 0.890 rs1585781 chr12:58056701 T/G cg15848620 chr12:58087721 OS9 -0.54 -7.31 -0.37 1.96e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg11279151 chr3:101281821 RG9MTD1 -0.52 -7.85 -0.39 5.54e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs4727027 0.933 rs12704063 chr7:148827909 T/C cg23583168 chr7:148888333 NA -0.74 -10.41 -0.49 3.17e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs67311347 1.000 rs7617989 chr3:40512463 A/G cg13409248 chr3:40428643 ENTPD3 -0.44 -7.45 -0.37 7.75e-13 Renal cell carcinoma; LIHC cis rs748404 0.723 rs565658 chr15:43556307 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.8 0.35 4.71e-11 Lung cancer; LIHC cis rs6690583 0.943 rs1837329 chr1:85469614 G/A cg22153463 chr1:85462885 MCOLN2 -0.46 -6.21 -0.32 1.56e-9 Serum sulfate level; LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg26354017 chr1:205819088 PM20D1 0.8 11.85 0.54 2.2e-27 Menarche (age at onset); LIHC cis rs8180040 0.701 rs13066214 chr3:47033937 C/T cg27129171 chr3:47204927 SETD2 0.65 11.32 0.52 1.84e-25 Colorectal cancer; LIHC cis rs743757 0.938 rs2236959 chr3:50441627 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.54 8.54 0.42 4.53e-16 Diastolic blood pressure; LIHC cis rs9790314 0.846 rs9815222 chr3:160994897 C/T cg03342759 chr3:160939853 NMD3 -0.82 -13.5 -0.59 1.33e-33 Morning vs. evening chronotype; LIHC cis rs600806 0.854 rs3768496 chr1:109866569 T/A cg23091122 chr1:110024289 SYPL2 -0.45 -5.93 -0.31 7.4e-9 Intelligence (multi-trait analysis); LIHC cis rs10752881 1.000 rs10752885 chr1:182982878 C/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.68 0.5 3.61e-23 Colorectal cancer; LIHC cis rs736408 0.648 rs3774354 chr3:52817675 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.48 7.66 0.38 1.92e-13 Bipolar disorder; LIHC cis rs1843834 0.539 rs6713629 chr2:225410973 A/T cg22455342 chr2:225449267 CUL3 0.58 8.33 0.41 2.04e-15 IgE levels in asthmatics (D.p. specific); LIHC cis rs10503871 0.740 rs13249960 chr8:30417532 C/G cg26383811 chr8:30366931 RBPMS 0.45 7.47 0.37 6.94e-13 Metabolite levels (X-11787); LIHC cis rs9818758 0.607 rs73074866 chr3:49626666 C/T cg07636037 chr3:49044803 WDR6 -0.66 -6.17 -0.32 1.95e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2250402 0.510 rs6492926 chr15:40325829 T/G cg10636054 chr15:40330586 SRP14 0.69 8.3 0.41 2.53e-15 Corneal curvature; LIHC trans rs4843747 0.749 rs13333619 chr16:88072076 C/T cg26811252 chr16:29126840 RRN3P2 0.54 8.77 0.43 8.31e-17 Menopause (age at onset); LIHC cis rs11971779 0.680 rs6960876 chr7:139112176 C/T cg07862535 chr7:139043722 LUC7L2 -0.59 -10.17 -0.48 2.15e-21 Diisocyanate-induced asthma; LIHC cis rs644148 0.803 rs2686771 chr19:44999494 T/C cg15540054 chr19:45004280 ZNF180 -0.76 -11.46 -0.53 5.97e-26 Personality dimensions; LIHC cis rs1577917 1.000 rs955196 chr6:86729951 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.51 8.85 0.43 4.63e-17 Response to antipsychotic treatment; LIHC cis rs7666738 0.791 rs34790496 chr4:98930516 C/T cg05340658 chr4:99064831 C4orf37 0.7 12.96 0.57 1.54e-31 Colonoscopy-negative controls vs population controls; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg05871582 chr8:648014 ERICH1 0.44 6.29 0.32 9.84e-10 Bilirubin levels; LIHC cis rs2066819 1.000 rs773664 chr12:56702176 C/T cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Psoriasis vulgaris; LIHC cis rs17270561 0.514 rs10946805 chr6:26077891 C/T cg17691542 chr6:26056736 HIST1H1C 1.02 12.83 0.57 5.14e-31 Iron status biomarkers; LIHC cis rs9918079 0.560 rs10008975 chr4:15624571 C/T cg21329975 chr4:15471214 CC2D2A -0.41 -6.16 -0.32 2.06e-9 Obesity-related traits; LIHC cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg16822855 chr3:40428330 ENTPD3 0.34 6.18 0.32 1.82e-9 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20390613 chr1:12678355 DHRS3 0.43 6.04 0.31 4.03e-9 Pancreatic cancer; LIHC trans rs11039798 0.920 rs8186465 chr11:48796771 T/C cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs1348850 0.554 rs7595576 chr2:178371921 C/T cg27490568 chr2:178487706 NA 1.11 12.06 0.55 3.7e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs722599 0.683 rs10144845 chr14:75237770 C/T cg08847533 chr14:75593920 NEK9 0.48 7.31 0.37 1.88e-12 IgG glycosylation; LIHC cis rs1008375 1.000 rs1008375 chr4:17682834 T/C cg02297831 chr4:17616191 MED28 0.4 6.48 0.33 3.14e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6783573 0.965 rs3806703 chr3:46618501 T/C cg21489266 chr3:46619131 LRRC2;TDGF1 -0.41 -6.56 -0.33 2.04e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2070488 0.930 rs928813 chr3:38528537 G/T cg24069376 chr3:38537580 EXOG 0.43 8.0 0.4 1.98e-14 Electrocardiographic conduction measures; LIHC trans rs1005277 0.563 rs2505216 chr10:38482830 T/C cg17830980 chr10:43048298 ZNF37B -0.52 -10.18 -0.48 2e-21 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.683 rs11522927 chr12:38137537 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.84 0.3 1.24e-8 Bladder cancer; LIHC cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg13047869 chr3:10149882 C3orf24 0.55 6.95 0.35 1.82e-11 Alzheimer's disease; LIHC cis rs7904368 0.901 rs7923189 chr10:16850214 C/T cg23933602 chr10:16859644 RSU1 0.6 6.21 0.32 1.56e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs2997447 0.846 rs61775425 chr1:26405634 A/T cg19633962 chr1:26362018 EXTL1 -0.64 -5.91 -0.3 8.34e-9 QRS complex (12-leadsum); LIHC cis rs1552244 0.554 rs7349576 chr3:10050893 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.75 0.39 1.03e-13 Alzheimer's disease; LIHC cis rs6752107 0.901 rs2289477 chr2:234160345 T/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.29 0.41 2.57e-15 Crohn's disease;Inflammatory bowel disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00137585 chr16:3450828 ZNF174;ZNF434 0.49 6.18 0.32 1.83e-9 Lung function (FEV1/FVC); LIHC cis rs1707322 0.721 rs11211165 chr1:46157906 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.74 0.39 1.11e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs34172651 0.517 rs11862923 chr16:24767303 G/T cg00339695 chr16:24857497 SLC5A11 0.73 11.09 0.51 1.23e-24 Intelligence (multi-trait analysis); LIHC cis rs8103278 0.507 rs4802276 chr19:46260748 T/C cg14061069 chr19:46274453 DMPK 0.71 13.27 0.58 1.06e-32 Coronary artery disease; LIHC cis rs7539409 0.915 rs4001467 chr1:84275858 A/T cg10977910 chr1:84465055 TTLL7 -0.75 -6.56 -0.33 1.94e-10 Alzheimer's disease; LIHC cis rs1401454 1.000 rs1519125 chr11:16244588 G/C cg02656851 chr11:16430247 SOX6 -0.32 -6.14 -0.32 2.23e-9 Blood pressure; LIHC cis rs7666738 0.830 rs17026973 chr4:98680041 T/A cg05340658 chr4:99064831 C4orf37 0.63 11.07 0.51 1.56e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg00091569 chr3:40428383 ENTPD3 0.39 6.52 0.33 2.5e-10 Renal cell carcinoma; LIHC cis rs763121 0.853 rs2267394 chr22:39101633 T/C cg21395723 chr22:39101663 GTPBP1 0.4 6.67 0.34 1.04e-10 Menopause (age at onset); LIHC cis rs7044106 0.791 rs3904196 chr9:123480369 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.12 0.52 1.02e-24 Hip circumference adjusted for BMI; LIHC trans rs875971 0.545 rs6969224 chr7:65834998 T/G cg26939375 chr7:64535504 NA 0.4 6.25 0.32 1.24e-9 Aortic root size; LIHC cis rs4908768 1.000 rs11121203 chr1:8648240 T/C cg20416874 chr1:8611966 RERE 0.54 6.93 0.35 2.15e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6942756 0.713 rs692597 chr7:129132554 T/G cg02491457 chr7:128862824 NA -0.54 -8.31 -0.41 2.21e-15 White matter hyperintensity burden; LIHC trans rs7714584 1.000 rs73284141 chr5:150266086 A/G cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs700651 0.789 rs1813106 chr2:198880589 A/G cg03934865 chr2:198174659 NA 0.43 6.23 0.32 1.33e-9 Intracranial aneurysm; LIHC cis rs11676348 0.818 rs6436031 chr2:218979259 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.43 -5.93 -0.31 7.47e-9 Ulcerative colitis; LIHC cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg27211696 chr2:191398769 TMEM194B -0.66 -11.07 -0.51 1.48e-24 Pulse pressure; LIHC cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.39 -0.33 5.31e-10 Gut microbiome composition (summer); LIHC cis rs1552244 0.882 rs7633769 chr3:10020622 C/T cg13047869 chr3:10149882 C3orf24 0.41 5.76 0.3 1.87e-8 Alzheimer's disease; LIHC trans rs3942852 0.688 rs10742834 chr11:48169717 G/A cg15704280 chr7:45808275 SEPT13 -0.59 -8.01 -0.4 1.77e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs9457247 1.000 rs422780 chr6:167406209 A/G cg12798992 chr6:167411361 FGFR1OP 0.6 9.93 0.47 1.36e-20 Crohn's disease; LIHC cis rs2242420 0.920 rs829413 chr1:21956050 C/G cg18150885 chr1:21978612 RAP1GAP -0.46 -5.73 -0.3 2.25e-8 Hematological and biochemical traits; LIHC cis rs7267979 1.000 rs910997 chr20:25267301 G/A cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg07414643 chr4:187882934 NA -0.23 -5.89 -0.3 9.47e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12594515 1.000 rs12595137 chr15:45986105 G/T cg01629716 chr15:45996671 NA 0.52 9.6 0.46 1.77e-19 Waist circumference;Weight; LIHC cis rs11955398 0.716 rs1379114 chr5:59997798 A/G cg02684056 chr5:59996105 DEPDC1B 0.4 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.721 rs7520123 chr1:46235219 C/G cg03146154 chr1:46216737 IPP 0.56 9.75 0.47 5.44e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.928 rs7527244 chr1:46368772 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.39 0.33 5.51e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2243480 1.000 rs13237037 chr7:65997882 T/C cg07424592 chr7:64974309 NA 0.78 8.94 0.44 2.44e-17 Diabetic kidney disease; LIHC cis rs1707322 1.000 rs11211219 chr1:46359478 G/C cg06784218 chr1:46089804 CCDC17 0.35 6.24 0.32 1.32e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1799949 0.536 rs4793227 chr17:41412250 A/C cg05368731 chr17:41323189 NBR1 0.66 10.91 0.51 5.54e-24 Menopause (age at onset); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13559217 chr19:5119331 KDM4B 0.49 6.41 0.33 4.7e-10 Systolic blood pressure; LIHC cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg19318889 chr4:1322082 MAEA -0.63 -10.11 -0.48 3.46e-21 Obesity-related traits; LIHC cis rs2404602 0.735 rs4886805 chr15:76739384 A/G cg03037974 chr15:76606532 NA 0.63 11.16 0.52 7.43e-25 Blood metabolite levels; LIHC cis rs2710247 1 rs2710247 chr2:219467508 A/G cg18887096 chr2:219472410 PLCD4 0.36 6.31 0.32 8.61e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs7618501 0.669 rs2230590 chr3:49936102 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.61 9.66 0.46 1.12e-19 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg00166722 chr3:10149974 C3orf24 0.47 5.75 0.3 1.94e-8 Alzheimer's disease; LIHC cis rs7818688 0.697 rs75349998 chr8:95990918 G/A cg16049864 chr8:95962084 TP53INP1 0.59 6.37 0.33 6.09e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1670533 1.000 rs10026482 chr4:1051128 C/G cg27284194 chr4:1044797 NA 0.6 9.02 0.44 1.36e-17 Recombination rate (females); LIHC cis rs12477438 0.520 rs2516830 chr2:99773702 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs7937890 0.559 rs2597217 chr11:14532883 A/G cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs9660992 0.710 rs1768586 chr1:205238275 A/G cg21545522 chr1:205238299 TMCC2 0.39 7.62 0.38 2.54e-13 Mean corpuscular volume;Mean platelet volume; LIHC cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg14393609 chr7:65229607 NA -0.43 -6.36 -0.33 6.33e-10 Aortic root size; LIHC cis rs763121 0.853 rs5757193 chr22:39034867 A/G cg14440974 chr22:39074834 NA 0.43 6.71 0.34 8.11e-11 Menopause (age at onset); LIHC cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg07424592 chr7:64974309 NA 0.82 9.55 0.46 2.54e-19 Diabetic kidney disease; LIHC cis rs3924048 0.574 rs11121930 chr1:12616956 C/A cg00291366 chr1:12616550 NA 0.44 8.97 0.44 1.95e-17 Optic cup area; LIHC cis rs924607 0.966 rs1709554 chr5:637443 A/G cg24163568 chr5:669837 TPPP 0.39 8.21 0.41 4.7e-15 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4474465 1.000 rs10793313 chr11:78169310 C/T cg02023728 chr11:77925099 USP35 0.35 6.29 0.32 9.61e-10 Alzheimer's disease (survival time); LIHC cis rs2153535 0.580 rs1932284 chr6:8477694 A/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.03e-14 Motion sickness; LIHC cis rs1664789 0.935 rs1694055 chr5:53276568 G/A ch.5.1024479R chr5:53302184 ARL15 0.5 8.09 0.4 1.06e-14 Waist circumference adjusted for body mass index; LIHC cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg24675658 chr1:53192096 ZYG11B 0.63 10.23 0.48 1.29e-21 Monocyte count; LIHC cis rs11105298 0.891 rs4842662 chr12:89933446 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.44 -0.37 8.21e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs9682041 0.660 rs13089256 chr3:170113601 G/A cg11886554 chr3:170076028 SKIL 0.63 5.84 0.3 1.23e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg22800045 chr5:56110881 MAP3K1 0.67 8.54 0.42 4.55e-16 Initial pursuit acceleration; LIHC cis rs950776 0.616 rs12901300 chr15:78892952 G/A cg06917634 chr15:78832804 PSMA4 0.64 8.91 0.43 3.17e-17 Sudden cardiac arrest; LIHC cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg06640241 chr16:89574553 SPG7 0.81 15.06 0.63 1.13e-39 Multiple myeloma (IgH translocation); LIHC cis rs7095944 0.614 rs61872084 chr10:126439062 C/T cg08799069 chr10:126477246 METTL10 -0.37 -6.48 -0.33 3.29e-10 Asthma; LIHC cis rs6430585 0.528 rs75667274 chr2:136682486 C/T cg25344623 chr2:136566232 LCT -0.39 -6.04 -0.31 3.95e-9 Corneal structure; LIHC cis rs7727544 0.735 rs272842 chr5:131656517 A/G cg07395648 chr5:131743802 NA -0.33 -6.95 -0.35 1.89e-11 Blood metabolite levels; LIHC cis rs2075371 0.764 rs1643034 chr7:134006176 A/G cg11752832 chr7:134001865 SLC35B4 0.42 6.38 0.33 5.61e-10 Mean platelet volume; LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg06873352 chr17:61820015 STRADA 0.74 13.44 0.59 2.25e-33 Prudent dietary pattern; LIHC trans rs4843747 0.518 rs4072777 chr16:88107030 G/A cg26811252 chr16:29126840 RRN3P2 0.42 6.8 0.35 4.59e-11 Menopause (age at onset); LIHC cis rs506338 0.517 rs490192 chr11:64471369 C/T cg08800856 chr11:64428347 NRXN2 0.38 5.9 0.3 8.6e-9 Body mass index;Urate levels; LIHC cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.55 0.38 3.95e-13 Electroencephalogram traits; LIHC cis rs8141529 0.702 rs469990 chr22:29304200 A/T cg02153584 chr22:29168773 CCDC117 0.51 7.99 0.4 2.09e-14 Lymphocyte counts; LIHC cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg25072359 chr17:41440525 NA 0.39 6.19 0.32 1.73e-9 Menopause (age at onset); LIHC cis rs2274273 0.905 rs28429419 chr14:55574793 T/C cg01864836 chr14:55583639 NA -0.43 -8.44 -0.42 9.04e-16 Protein biomarker; LIHC cis rs9818758 0.607 rs34326553 chr3:49134429 A/G cg07636037 chr3:49044803 WDR6 -0.81 -8.4 -0.41 1.2e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9682041 0.696 rs16855034 chr3:170097842 C/G cg11886554 chr3:170076028 SKIL 0.63 5.8 0.3 1.5e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs8103278 0.507 rs7246377 chr19:46292259 G/A cg11657440 chr19:46296263 DMWD 0.67 12.33 0.55 3.64e-29 Coronary artery disease; LIHC cis rs1577917 1.000 rs13199006 chr6:86608708 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.76 -0.39 9.97e-14 Response to antipsychotic treatment; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg15910486 chr5:142783621 NR3C1 -0.46 -6.12 -0.31 2.62e-9 Longevity; LIHC trans rs867371 1.000 rs1174543 chr15:82448073 C/T cg18393722 chr15:85113863 UBE2QP1 0.41 7.0 0.35 1.39e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs4862750 0.872 rs4862748 chr4:187877388 C/T cg22105103 chr4:187893119 NA -0.23 -5.73 -0.3 2.17e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs929354 0.685 rs7807856 chr7:156934498 T/C cg17757837 chr7:157058334 UBE3C 0.72 11.6 0.53 1.79e-26 Body mass index; LIHC cis rs9790314 1.000 rs336585 chr3:161081670 A/G cg03342759 chr3:160939853 NMD3 -0.71 -8.45 -0.42 8.65e-16 Morning vs. evening chronotype; LIHC cis rs1008375 1.000 rs2058337 chr4:17678649 C/T cg02297831 chr4:17616191 MED28 0.4 6.56 0.33 1.98e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2120019 0.938 rs59094290 chr15:75308561 G/T cg09165964 chr15:75287851 SCAMP5 -0.61 -9.46 -0.46 5.24e-19 Blood trace element (Zn levels); LIHC cis rs35306767 0.953 rs12259338 chr10:969377 C/T cg20503657 chr10:835505 NA 0.89 10.69 0.5 3.45e-23 Eosinophil percentage of granulocytes; LIHC cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg19729930 chr2:74357872 NA 0.85 19.65 0.73 4.55e-58 Gestational age at birth (maternal effect); LIHC cis rs317689 0.690 rs10878947 chr12:69642683 A/T cg20891283 chr12:69753455 YEATS4 0.48 6.82 0.35 4.18e-11 Response to diuretic therapy; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.03 -0.31 4.34e-9 Total body bone mineral density; LIHC cis rs908922 0.676 rs10888494 chr1:152514709 T/C cg20991723 chr1:152506922 NA 0.53 9.23 0.45 2.89e-18 Hair morphology; LIHC cis rs9733 0.596 rs2065900 chr1:150652202 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.2 0.32 1.67e-9 Tonsillectomy; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg12311636 chr6:118886798 C6orf204 -0.52 -6.23 -0.32 1.35e-9 Diastolic blood pressure; LIHC cis rs12701220 0.947 rs1007765 chr7:1032805 G/C cg00990874 chr7:1149470 C7orf50 -0.7 -9.36 -0.45 1.1e-18 Bronchopulmonary dysplasia; LIHC cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC cis rs11971779 0.680 rs11760420 chr7:139114768 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.29 0.49 8.39e-22 Diisocyanate-induced asthma; LIHC cis rs6840360 0.550 rs7683134 chr4:152503362 A/C cg22705602 chr4:152727874 NA -0.33 -6.36 -0.33 6.35e-10 Intelligence (multi-trait analysis); LIHC trans rs208520 0.690 rs1351867 chr6:66760995 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.81 9.14 0.44 5.59e-18 Exhaled nitric oxide output; LIHC cis rs12477438 0.798 rs10198293 chr2:99602929 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.71 -0.65 3.04e-42 Chronic sinus infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20743544 chr7:32982957 RP9P 0.45 6.34 0.32 7.26e-10 Pancreatic cancer; LIHC cis rs6912958 1.000 rs2223880 chr6:88167897 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.14 -0.36 5.71e-12 Monocyte percentage of white cells; LIHC cis rs9649213 0.593 rs7797943 chr7:97946902 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs79057730 0.528 rs6965219 chr7:821807 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.74 8.4 0.41 1.19e-15 Initial pursuit acceleration; LIHC cis rs11711311 1.000 rs2566970 chr3:113462123 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 -0.41 -7.57 -0.38 3.39e-13 IgG glycosylation; LIHC cis rs17376456 0.825 rs6874766 chr5:93213807 C/G cg25358565 chr5:93447407 FAM172A -1.03 -9.32 -0.45 1.46e-18 Diabetic retinopathy; LIHC cis rs36051895 0.658 rs10974914 chr9:5014332 C/T cg02405213 chr9:5042618 JAK2 -0.69 -12.4 -0.56 2e-29 Pediatric autoimmune diseases; LIHC cis rs2239547 0.563 rs4687560 chr3:52898121 T/G cg11645453 chr3:52864694 ITIH4 0.33 8.52 0.42 5.22e-16 Schizophrenia; LIHC cis rs8017423 0.935 rs7158410 chr14:90704370 T/C cg14092571 chr14:90743983 NA -0.37 -5.87 -0.3 1.04e-8 Mortality in heart failure; LIHC cis rs6570726 0.791 rs6900040 chr6:145893134 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.24 0.32 1.32e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7481584 0.581 rs399565 chr11:3061780 C/T cg25174290 chr11:3078921 CARS -0.42 -6.29 -0.32 9.9e-10 Calcium levels; LIHC cis rs765787 0.530 rs4774542 chr15:45526026 A/C cg24006582 chr15:45444508 DUOX1 0.49 6.93 0.35 2.13e-11 Uric acid levels; LIHC cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg19539972 chr4:7069911 GRPEL1 0.67 9.68 0.46 9.29e-20 Monocyte percentage of white cells; LIHC cis rs17539620 0.628 rs62432728 chr6:154829511 G/C cg17771515 chr6:154831774 CNKSR3 0.59 6.27 0.32 1.1e-9 Lipoprotein (a) levels; LIHC cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg00149659 chr3:10157352 C3orf10 0.66 6.49 0.33 2.94e-10 Alzheimer's disease; LIHC cis rs11148252 0.557 rs9536223 chr13:53233194 A/T cg02158880 chr13:53174818 NA 0.38 5.91 0.3 8.14e-9 Lewy body disease; LIHC cis rs67311347 0.955 rs6764102 chr3:40378153 C/G cg00656387 chr3:40428638 ENTPD3 0.41 6.62 0.34 1.38e-10 Renal cell carcinoma; LIHC cis rs8078723 1.000 rs4795418 chr17:38164851 T/C cg17467752 chr17:38218738 THRA 0.76 13.99 0.6 1.82e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6748734 0.948 rs4471886 chr2:241838622 T/C cg04034577 chr2:241836375 C2orf54 -0.49 -11.5 -0.53 4.35e-26 Urinary metabolites; LIHC cis rs796364 0.616 rs2140486 chr2:200690102 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.16 0.32 2.03e-9 Schizophrenia; LIHC cis rs2302190 0.882 rs6503859 chr17:56460852 C/G cg05425664 chr17:57184151 TRIM37 -0.46 -5.75 -0.3 1.93e-8 Vitamin D levels; LIHC cis rs3806843 0.933 rs2879087 chr5:140188575 G/C cg26395211 chr5:140044315 WDR55 -0.42 -6.22 -0.32 1.46e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1043515 0.748 rs11653487 chr17:36942631 A/G cg09592244 chr17:37024020 NA -0.4 -6.74 -0.34 6.89e-11 Height; LIHC cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg09222892 chr1:25734099 RHCE 0.41 7.3 0.37 2.05e-12 Plateletcrit;Mean corpuscular volume; LIHC trans rs2243480 0.901 rs35823062 chr7:65965821 A/G cg10756647 chr7:56101905 PSPH 1.03 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs1878931 0.624 rs37810 chr16:3451881 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -8.1 -0.4 9.64e-15 Body mass index (adult); LIHC cis rs10840270 0.672 rs12273601 chr11:9636854 C/T cg26541003 chr11:9594436 WEE1 -0.42 -5.78 -0.3 1.7e-8 Bacteremia; LIHC cis rs965469 0.779 rs967366 chr20:3266935 T/G cg25506879 chr20:3388711 C20orf194 -0.54 -6.63 -0.34 1.3e-10 IFN-related cytopenia; LIHC cis rs4820539 0.966 rs5751590 chr22:23486830 A/C cg14186256 chr22:23484241 RTDR1 0.96 20.32 0.74 9.35e-61 Bone mineral density; LIHC cis rs7216064 1.000 rs2365468 chr17:65841318 C/T cg12091567 chr17:66097778 LOC651250 -0.67 -9.7 -0.46 8.36e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2204008 0.775 rs2387809 chr12:38363338 T/A cg26384229 chr12:38710491 ALG10B 0.57 7.83 0.39 6.11e-14 Bladder cancer; LIHC cis rs7824557 0.767 rs3808513 chr8:11157460 G/T cg21775007 chr8:11205619 TDH -0.52 -8.06 -0.4 1.25e-14 Retinal vascular caliber; LIHC cis rs4713118 0.869 rs9461400 chr6:27700559 A/G cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs12458462 0.859 rs2242177 chr18:77477379 G/A cg11879182 chr18:77439856 CTDP1 0.82 13.71 0.6 2.09e-34 Monocyte count; LIHC cis rs1144333 0.655 rs968018 chr1:76395662 G/A cg03433033 chr1:76189801 ACADM 0.53 7.55 0.38 4.02e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs9308433 0.529 rs4655246 chr1:214502898 G/C cg06198575 chr1:214491504 SMYD2 0.55 5.76 0.3 1.87e-8 IgG glycosylation; LIHC cis rs929354 1.000 rs1182381 chr7:157043473 G/A cg17757837 chr7:157058334 UBE3C -0.8 -14.12 -0.61 5.66e-36 Body mass index; LIHC cis rs74233809 1.000 rs10883806 chr10:104713076 C/T cg03493300 chr10:104813866 CNNM2 0.45 5.91 0.3 8.45e-9 Birth weight; LIHC cis rs7223966 1.000 rs8077265 chr17:61732727 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 7.0 0.35 1.36e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2153535 0.580 rs2327057 chr6:8443319 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.66 0.42 1.91e-16 Motion sickness; LIHC cis rs2115536 1.000 rs2115540 chr15:80190308 A/G cg00225070 chr15:80189496 MTHFS 0.67 11.22 0.52 4.36e-25 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06970076 chr16:1560791 IFT140 0.45 6.48 0.33 3.25e-10 Longevity; LIHC cis rs9914988 0.943 rs4313850 chr17:27080768 T/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.96 -0.35 1.69e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.96 20.75 0.75 1.74e-62 Height; LIHC cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg11764359 chr7:65958608 NA 0.58 6.02 0.31 4.53e-9 Diabetic kidney disease; LIHC cis rs9612 0.950 rs7256472 chr19:44246970 C/T cg08581076 chr19:44259116 C19orf61 0.66 8.45 0.42 8.31e-16 Exhaled nitric oxide output; LIHC cis rs79387448 0.810 rs75218113 chr2:103239356 C/G cg09003973 chr2:102972529 NA 0.86 6.22 0.32 1.49e-9 Gut microbiota (bacterial taxa); LIHC cis rs4700695 0.719 rs153390 chr5:65431087 G/C cg21114390 chr5:65439923 SFRS12 -0.59 -8.46 -0.42 7.85e-16 Facial morphology (factor 19); LIHC cis rs2832191 0.935 rs11910316 chr21:30519729 G/A cg24692254 chr21:30365293 RNF160 -0.52 -9.11 -0.44 6.93e-18 Dental caries; LIHC cis rs3736485 0.966 rs7170217 chr15:51890678 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.37 -0.33 5.94e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7927771 0.524 rs1563821 chr11:47756568 C/T cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg08280861 chr8:58055591 NA 0.52 6.16 0.32 2.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs1335628 chr6:8491742 A/T cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs2066819 1.000 rs871130 chr12:56648777 A/G cg26734620 chr12:56694298 CS -1.21 -10.41 -0.49 3.22e-22 Psoriasis vulgaris; LIHC cis rs748404 0.697 rs579651 chr15:43558376 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.8 0.35 4.71e-11 Lung cancer; LIHC cis rs9420 0.961 rs11606396 chr11:57435211 C/T cg19752551 chr11:57585705 CTNND1 -0.53 -7.44 -0.37 8.4e-13 Schizophrenia; LIHC cis rs6746896 0.959 rs58361269 chr2:97403110 G/A cg26665480 chr2:98280029 ACTR1B 0.45 5.84 0.3 1.21e-8 Bipolar disorder; LIHC cis rs7312933 0.558 rs11181483 chr12:42798384 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 8.05 0.4 1.37e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4906332 1.000 rs12892062 chr14:103883512 A/G cg19000871 chr14:103996768 TRMT61A -0.45 -7.71 -0.38 1.41e-13 Coronary artery disease; LIHC cis rs10870270 1.000 rs10870270 chr10:133754334 G/A cg08754478 chr10:133766260 PPP2R2D -0.56 -8.23 -0.41 3.96e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9790314 0.779 rs1599374 chr3:160891727 G/A cg03342759 chr3:160939853 NMD3 -0.75 -9.31 -0.45 1.62e-18 Morning vs. evening chronotype; LIHC cis rs7172677 0.768 rs72730583 chr15:75351630 T/C cg09165964 chr15:75287851 SCAMP5 0.52 7.5 0.38 5.72e-13 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2836950 0.501 rs13047518 chr21:40707307 G/A cg11890956 chr21:40555474 PSMG1 -0.46 -7.4 -0.37 1.07e-12 Menarche (age at onset); LIHC cis rs1559088 0.576 rs4805852 chr19:33609441 C/T cg27124370 chr19:33622961 WDR88 0.59 8.88 0.43 3.93e-17 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs151997 0.671 rs395557 chr5:50215832 G/T cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC cis rs2832191 0.716 rs2249028 chr21:30365322 G/A cg24692254 chr21:30365293 RNF160 0.86 15.65 0.65 5.1e-42 Dental caries; LIHC cis rs9549367 0.713 rs1755690 chr13:113824266 T/C cg00898013 chr13:113819073 PROZ 0.34 5.9 0.3 8.78e-9 Platelet distribution width; LIHC cis rs2991971 0.869 rs2453404 chr1:46014735 A/G cg24296786 chr1:45957014 TESK2 0.5 7.18 0.36 4.44e-12 High light scatter reticulocyte count; LIHC cis rs9858542 0.953 rs10640 chr3:49454277 G/A cg03060546 chr3:49711283 APEH -0.47 -6.46 -0.33 3.56e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9649213 0.614 rs2240348 chr7:97984077 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.57 -10.06 -0.48 4.98e-21 Prostate cancer (SNP x SNP interaction); LIHC trans rs1075232 1.000 rs34959140 chr15:31725223 G/A cg17859187 chr1:168147929 TIPRL 0.75 6.04 0.31 3.96e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg03721293 chr16:90014378 DEF8 0.39 6.52 0.33 2.48e-10 Skin colour saturation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13961709 chr14:74486189 C14orf45;ENTPD5 0.44 6.59 0.34 1.69e-10 Cognitive function; LIHC cis rs74417235 0.517 rs13179034 chr5:154059487 C/A cg08893839 chr5:154027129 NA 0.49 6.74 0.34 6.64e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs546131 0.642 rs35617374 chr11:34832373 A/G cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.62 -0.34 1.36e-10 Lung disease severity in cystic fibrosis; LIHC cis rs1728785 1.000 rs1624718 chr16:68580385 A/G cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs1023500 0.505 rs134891 chr22:42675882 T/C cg15557168 chr22:42548783 NA -0.36 -6.24 -0.32 1.28e-9 Schizophrenia; LIHC cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg02564969 chr6:151773285 C6orf211;RMND1 0.52 7.99 0.4 2.03e-14 Menarche (age at onset); LIHC cis rs875971 0.862 rs1968126 chr7:66057004 A/G cg18876405 chr7:65276391 NA -0.34 -6.3 -0.32 9.23e-10 Aortic root size; LIHC cis rs1419980 0.673 rs12146828 chr12:7739341 C/G cg14906510 chr12:7781169 NA -0.43 -6.58 -0.34 1.81e-10 HDL cholesterol levels; LIHC cis rs769267 0.929 rs2905431 chr19:19482882 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 -0.39 -5.94 -0.31 6.83e-9 Tonsillectomy; LIHC cis rs2522056 1.000 rs1003533 chr5:131755651 C/T cg24060327 chr5:131705240 SLC22A5 0.62 8.39 0.41 1.29e-15 Lymphocyte counts;Fibrinogen; LIHC cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg22800045 chr5:56110881 MAP3K1 0.67 8.53 0.42 4.66e-16 Initial pursuit acceleration; LIHC cis rs10504229 0.593 rs113184543 chr8:58042950 A/G cg02290350 chr8:58132656 NA 0.32 7.09 0.36 7.94e-12 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.08 -0.31 3.3e-9 Total body bone mineral density; LIHC cis rs7223966 0.921 rs3020612 chr17:61960878 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.52 0.33 2.51e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9733 0.596 rs34600506 chr1:150687808 C/G cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC trans rs1814175 0.817 rs28544182 chr11:50049577 G/T cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs9918079 0.560 rs4270584 chr4:15600799 A/G cg04067612 chr4:15429572 C1QTNF7 0.3 6.4 0.33 4.99e-10 Obesity-related traits; LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg17280350 chr2:20853360 NA -0.43 -6.32 -0.32 8.14e-10 Gut microbiome composition (summer); LIHC cis rs6545883 0.860 rs13023037 chr2:61620989 C/T cg14146966 chr2:61757674 XPO1 -0.44 -7.48 -0.38 6.25e-13 Tuberculosis; LIHC cis rs7546 0.504 rs2075636 chr16:4938321 A/T cg08329684 chr16:4932620 PPL -0.42 -7.34 -0.37 1.53e-12 Cancer; LIHC cis rs7520050 0.872 rs2486445 chr1:46605369 C/T cg23431851 chr1:46668822 C1orf190;POMGNT1 0.38 5.78 0.3 1.72e-8 Red blood cell count;Reticulocyte count; LIHC cis rs6728642 0.908 rs11901495 chr2:98017804 A/G cg26665480 chr2:98280029 ACTR1B 0.61 6.92 0.35 2.27e-11 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs72781680 0.612 rs33913065 chr2:24344060 T/G cg06627628 chr2:24431161 ITSN2 -0.62 -7.33 -0.37 1.64e-12 Lymphocyte counts; LIHC trans rs9388451 0.839 rs3799709 chr6:126078361 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.56 -9.11 -0.44 7.02e-18 Brugada syndrome; LIHC cis rs62158211 0.691 rs1964463 chr2:114069021 C/T cg17784749 chr2:114082611 LOC440839 -0.58 -7.44 -0.37 8.11e-13 Sleep duration (oversleepers vs undersleepers);Sleep traits (multi-trait analysis);Sleep duration; LIHC cis rs1348850 0.915 rs10930798 chr2:178446141 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.75 11.25 0.52 3.38e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7927771 0.524 rs12421563 chr11:47780222 G/A cg20307385 chr11:47447363 PSMC3 -0.65 -9.85 -0.47 2.68e-20 Subjective well-being; LIHC cis rs7552404 1.000 rs7552404 chr1:76135946 A/G cg10523679 chr1:76189770 ACADM 0.65 9.23 0.45 2.86e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2153535 0.580 rs1115078 chr6:8449638 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs6542838 0.704 rs12474283 chr2:99527310 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.63 -0.34 1.33e-10 Fear of minor pain; LIHC cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg13271783 chr10:134563150 INPP5A 0.61 7.28 0.37 2.33e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg11062466 chr8:58055876 NA 0.51 6.66 0.34 1.07e-10 Developmental language disorder (linguistic errors); LIHC cis rs7587476 0.601 rs1129804 chr2:215674323 C/G cg04004882 chr2:215674386 BARD1 -0.58 -8.18 -0.4 5.5e-15 Neuroblastoma; LIHC cis rs3768617 0.677 rs12739316 chr1:183052080 G/A ch.1.3577855R chr1:183094577 LAMC1 0.52 8.33 0.41 1.95e-15 Fuchs's corneal dystrophy; LIHC cis rs7106204 0.748 rs6484024 chr11:24210079 T/C ch.11.24196551F chr11:24239977 NA 0.76 10.01 0.48 7.62e-21 Response to Homoharringtonine (cytotoxicity); LIHC cis rs7818688 0.697 rs77805255 chr8:95983566 G/A cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7959452 0.535 rs10784771 chr12:69621264 A/G cg20891283 chr12:69753455 YEATS4 0.74 13.56 0.59 7.94e-34 Blood protein levels; LIHC cis rs10876993 0.890 rs812304 chr12:58074853 A/C cg18357645 chr12:58087776 OS9 0.51 8.46 0.42 7.74e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs116095464 0.558 rs10068203 chr5:206618 C/T cg22496380 chr5:211416 CCDC127 -1.19 -10.49 -0.49 1.66e-22 Breast cancer; LIHC cis rs6840360 0.571 rs4696270 chr4:152498289 G/A cg22705602 chr4:152727874 NA -0.33 -6.48 -0.33 3.29e-10 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.967 rs4900030 chr14:90689813 T/A cg14092571 chr14:90743983 NA -0.37 -5.79 -0.3 1.59e-8 Mortality in heart failure; LIHC cis rs35110281 0.627 rs56369437 chr21:44970275 A/G cg01579765 chr21:45077557 HSF2BP -0.31 -5.97 -0.31 5.91e-9 Mean corpuscular volume; LIHC cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs826838 0.967 rs1719854 chr12:39127707 G/A cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs861020 0.563 rs12046618 chr1:210043135 C/T cg05527609 chr1:210001259 C1orf107 0.84 11.15 0.52 7.6e-25 Orofacial clefts; LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.1 0.4 9.76e-15 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13425677 chr5:56112090 MAP3K1 -0.54 -7.15 -0.36 5.14e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg13552506 chr1:946444 NA 0.47 6.84 0.35 3.67e-11 Bilirubin levels; LIHC cis rs11792861 0.781 rs2151426 chr9:111743797 A/C cg05043794 chr9:111880884 C9orf5 -0.3 -7.04 -0.36 1.06e-11 Menarche (age at onset); LIHC cis rs35110281 0.807 rs9976441 chr21:45046591 G/A cg21573476 chr21:45109991 RRP1B -0.53 -10.05 -0.48 5.31e-21 Mean corpuscular volume; LIHC cis rs990171 0.607 rs2192752 chr2:102769373 A/C cg22835712 chr2:102737379 NA -0.52 -7.61 -0.38 2.72e-13 Lymphocyte counts; LIHC trans rs1728785 1.000 rs1728784 chr16:68591156 T/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.44 0.33 3.97e-10 Ulcerative colitis; LIHC cis rs10791097 0.677 rs11222359 chr11:130730648 A/G cg14779329 chr11:130786720 SNX19 0.39 5.95 0.31 6.72e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs17685 0.753 rs12531559 chr7:75631697 C/T cg19862616 chr7:65841803 NCRNA00174 -0.89 -17.88 -0.7 6.17e-51 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9467773 1.000 rs9467783 chr6:26542894 C/T cg09904177 chr6:26538194 HMGN4 0.66 13.99 0.6 1.8e-35 Intelligence (multi-trait analysis); LIHC cis rs546131 0.614 rs12791769 chr11:34834268 A/G cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.59 -0.34 1.66e-10 Lung disease severity in cystic fibrosis; LIHC cis rs55665837 0.701 rs12286408 chr11:14579376 G/A cg25251204 chr11:14927456 NA 0.44 6.14 0.31 2.35e-9 Vitamin D levels; LIHC cis rs9910055 0.530 rs2269906 chr17:42294337 G/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.62 -8.91 -0.43 3.19e-17 Total body bone mineral density; LIHC cis rs882732 1.000 rs10139745 chr14:95035374 C/T cg14866387 chr14:95027382 SERPINA4 -0.43 -5.95 -0.31 6.5e-9 Blood protein levels; LIHC cis rs637571 0.522 rs1786175 chr11:65754808 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.4 6.02 0.31 4.48e-9 Eosinophil percentage of white cells; LIHC cis rs9818758 0.607 rs10049462 chr3:49309684 C/T cg07636037 chr3:49044803 WDR6 -0.82 -8.32 -0.41 2.09e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs875971 0.862 rs709596 chr7:65825913 A/G cg11764359 chr7:65958608 NA 0.84 14.95 0.63 3.09e-39 Aortic root size; LIHC cis rs7909074 1.000 rs4948927 chr10:45397071 G/A cg05187965 chr10:45406764 TMEM72 -0.27 -6.78 -0.34 5.29e-11 Mean corpuscular volume; LIHC cis rs644799 0.648 rs1016031 chr11:95473365 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.68 -11.3 -0.52 2.2e-25 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17258537 chr5:179401804 RNF130 -0.48 -7.14 -0.36 5.5e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs599083 0.530 rs640569 chr11:68184820 A/G cg01657329 chr11:68192670 LRP5 0.58 7.85 0.39 5.57e-14 Bone mineral density (spine); LIHC cis rs56235845 0.964 rs4075958 chr5:176784512 A/G cg17509989 chr5:176798049 RGS14 -0.85 -12.39 -0.56 2.3e-29 Hemoglobin concentration;Hematocrit; LIHC cis rs194045 0.609 rs252344 chr16:29184882 G/A cg16691023 chr16:29205632 NA -0.58 -8.67 -0.42 1.72e-16 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs9457247 0.561 rs916331 chr6:167470559 T/G cg23791538 chr6:167370224 RNASET2 -0.52 -7.84 -0.39 5.63e-14 Crohn's disease; LIHC cis rs8078723 1.000 rs3826331 chr17:38150492 T/C cg17467752 chr17:38218738 THRA -0.72 -13.0 -0.58 1.11e-31 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs35306767 0.807 rs61831436 chr10:837882 G/A cg10556349 chr10:835070 NA 0.65 5.75 0.3 1.94e-8 Eosinophil percentage of granulocytes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04578738 chr17:34136331 TAF15 0.39 6.21 0.32 1.5e-9 Cognitive function; LIHC trans rs79976124 0.879 rs12214239 chr6:66636059 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.62 0.34 1.36e-10 Type 2 diabetes; LIHC trans rs6600671 1.000 rs4844380 chr1:121193620 A/T cg09829573 chr1:144692074 NBPF9 -0.41 -7.27 -0.37 2.5e-12 Hip geometry; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02092906 chr6:83903419 PGM3;RWDD2A 0.49 6.54 0.33 2.26e-10 Lung function (FEV1/FVC); LIHC cis rs12594515 0.967 rs11856523 chr15:45989495 C/T cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC cis rs9914988 0.943 rs9890377 chr17:27111111 A/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs2841277 0.708 rs11623422 chr14:105407031 A/G cg15352829 chr14:105391018 PLD4 -0.43 -9.23 -0.45 2.83e-18 Rheumatoid arthritis; LIHC cis rs6088590 1.000 rs1998028 chr20:33344595 A/T cg24642439 chr20:33292090 TP53INP2 0.8 11.62 0.53 1.57e-26 Coronary artery disease; LIHC cis rs7131987 0.903 rs11050152 chr12:29404424 G/T cg12903224 chr12:29470962 FAR2 -0.4 -6.42 -0.33 4.56e-10 QT interval; LIHC cis rs57590327 0.503 rs13075250 chr3:81907952 T/C cg07356753 chr3:81810745 GBE1 -0.5 -7.63 -0.38 2.3e-13 Extraversion; LIHC cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg11890956 chr21:40555474 PSMG1 1.06 15.39 0.64 5.35e-41 Cognitive function; LIHC cis rs116095464 0.558 rs7731089 chr5:290422 A/C cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs829883 0.616 rs249832 chr12:98832387 C/T cg25150519 chr12:98850993 NA 0.68 10.72 0.5 2.59e-23 Colorectal adenoma (advanced); LIHC cis rs35306767 0.807 rs34885925 chr10:919032 G/C cg26597838 chr10:835615 NA 1.46 16.73 0.67 2.42e-46 Eosinophil percentage of granulocytes; LIHC cis rs13108904 0.901 rs12641735 chr4:1304434 G/C cg00684032 chr4:1343700 KIAA1530 0.37 5.98 0.31 5.61e-9 Obesity-related traits; LIHC cis rs523522 0.962 rs4767902 chr12:120910004 C/T cg12219531 chr12:120966889 COQ5 0.65 12.61 0.56 3.24e-30 High light scatter reticulocyte count; LIHC cis rs611744 0.967 rs689256 chr8:109186398 T/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs9733 0.596 rs34140753 chr1:150642583 T/C cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs34638657 0.827 rs3829548 chr16:82206238 C/A cg07918374 chr16:82182319 MPHOSPH6 0.35 7.02 0.35 1.19e-11 Lung adenocarcinoma; LIHC trans rs459571 0.629 rs441233 chr9:136876021 A/G cg10765909 chr12:53715428 AAAS 0.43 6.56 0.33 1.98e-10 Platelet distribution width; LIHC cis rs5771242 0.518 rs6010216 chr22:50679471 C/T cg16473166 chr22:50639996 SELO 0.53 6.15 0.32 2.19e-9 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); LIHC cis rs6586163 1.000 rs7072828 chr10:90754953 T/G cg03111039 chr10:90751583 FAS;ACTA2 -0.56 -8.22 -0.41 4.2e-15 Chronic lymphocytic leukemia; LIHC trans rs801193 0.660 rs1016265 chr7:66214567 C/T cg10756647 chr7:56101905 PSPH 0.47 6.95 0.35 1.86e-11 Aortic root size; LIHC cis rs7572733 0.536 rs6732517 chr2:198912902 G/C cg03934865 chr2:198174659 NA 0.45 6.5 0.33 2.83e-10 Dermatomyositis; LIHC cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg17971929 chr21:40555470 PSMG1 0.85 10.53 0.49 1.2e-22 Cognitive function; LIHC cis rs240764 0.687 rs239248 chr6:101088315 T/A cg09795085 chr6:101329169 ASCC3 0.53 7.54 0.38 4.18e-13 Neuroticism; LIHC cis rs7071206 0.947 rs1356090 chr10:79395312 T/C cg07817648 chr10:79422355 NA -0.34 -7.2 -0.36 3.96e-12 Bone mineral density; LIHC trans rs1973993 0.567 rs2800433 chr1:96998126 T/A cg10631902 chr5:14652156 NA 0.34 8.06 0.4 1.33e-14 Weight; LIHC trans rs9836270 1.000 rs9836270 chr3:131916996 G/T cg14990970 chr19:58967158 ZNF324B -0.39 -6.18 -0.32 1.87e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7100689 0.622 rs1417221 chr10:82100428 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.38 0.49 3.89e-22 Post bronchodilator FEV1; LIHC trans rs11098499 0.863 rs34868248 chr4:120442430 A/G cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs1451375 0.652 rs7803788 chr7:50625898 A/G cg14593290 chr7:50529359 DDC -0.49 -7.96 -0.4 2.55e-14 Malaria; LIHC cis rs7772486 0.754 rs6922507 chr6:146250155 A/T cg13319975 chr6:146136371 FBXO30 0.38 6.04 0.31 3.92e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9291683 0.609 rs4622999 chr4:10003395 C/G cg11266682 chr4:10021025 SLC2A9 0.31 6.54 0.33 2.23e-10 Bone mineral density; LIHC cis rs9948 1.000 rs9973492 chr2:97498481 T/A cg01990225 chr2:97406019 LMAN2L -0.57 -5.89 -0.3 9.12e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs5769765 0.862 rs138870 chr22:50209737 C/T cg02269571 chr22:50332266 NA -0.65 -8.62 -0.42 2.55e-16 Schizophrenia; LIHC cis rs896854 0.517 rs10112447 chr8:95955701 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -7.45 -0.37 7.74e-13 Type 2 diabetes; LIHC trans rs2727020 0.729 rs685789 chr11:49241228 G/A cg03929089 chr4:120376271 NA 0.79 13.78 0.6 1.16e-34 Coronary artery disease; LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs72781680 0.898 rs12619525 chr2:23999565 G/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs311392 0.526 rs167474 chr8:55101321 A/C cg20636351 chr8:55087400 NA -0.34 -7.09 -0.36 7.97e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs765787 0.530 rs1648285 chr15:45517505 C/G cg25801113 chr15:45476975 SHF 0.36 6.01 0.31 4.63e-9 Uric acid levels; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg10150615 chr22:24372951 LOC391322 -0.47 -6.6 -0.34 1.58e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7552404 0.727 rs7521344 chr1:76318325 C/T cg10523679 chr1:76189770 ACADM -0.55 -6.9 -0.35 2.48e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs317689 0.718 rs160827 chr12:69770147 G/A cg19645103 chr12:69753606 YEATS4 -0.46 -6.28 -0.32 1e-9 Response to diuretic therapy; LIHC cis rs244293 0.965 rs244334 chr17:53204055 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.46 6.81 0.35 4.33e-11 Menarche (age at onset); LIHC cis rs17376456 1.000 rs61132622 chr5:93539684 G/A cg25358565 chr5:93447407 FAM172A 1.08 9.8 0.47 3.68e-20 Diabetic retinopathy; LIHC cis rs11673344 0.796 rs16971886 chr19:37487975 G/A cg27390819 chr19:37464633 NA -0.5 -6.05 -0.31 3.82e-9 Obesity-related traits; LIHC cis rs1003719 0.788 rs2835593 chr21:38465873 G/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs35110281 0.777 rs7276215 chr21:44990697 A/G cg01579765 chr21:45077557 HSF2BP -0.37 -6.88 -0.35 2.95e-11 Mean corpuscular volume; LIHC cis rs3617 0.625 rs6769789 chr3:52874446 C/T cg11645453 chr3:52864694 ITIH4 -0.22 -6.09 -0.31 2.97e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9534288 0.700 rs57192057 chr13:46592327 C/G cg15192986 chr13:46630673 CPB2 -0.54 -8.28 -0.41 2.9e-15 Blood protein levels; LIHC cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg13866156 chr1:1669148 SLC35E2 -0.67 -12.53 -0.56 6.71e-30 Body mass index; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg26816438 chr1:45139524 TMEM53;C1orf228 -0.38 -6.09 -0.31 2.99e-9 Triglycerides; LIHC trans rs4290604 0.748 rs10929216 chr2:238080938 C/T cg15676719 chr1:167598521 RCSD1 -0.46 -6.19 -0.32 1.77e-9 Asthma; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.692 rs12904198 chr15:77146978 G/A cg23625390 chr15:77176239 SCAPER 0.35 5.8 0.3 1.49e-8 Blood metabolite levels; LIHC cis rs3741404 0.583 rs640999 chr11:63869425 C/A cg05016508 chr11:63871570 FLRT1;MACROD1 0.41 6.58 0.34 1.78e-10 Platelet count; LIHC cis rs6714710 0.603 rs11678591 chr2:98541001 T/C cg26665480 chr2:98280029 ACTR1B 0.42 5.91 0.3 8.41e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs1577917 0.876 rs11752223 chr6:86573394 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.09 -0.4 1.06e-14 Response to antipsychotic treatment; LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.13 0.4 8.12e-15 Height; LIHC cis rs2153535 0.580 rs6920779 chr6:8437624 C/T cg07606381 chr6:8435919 SLC35B3 0.8 11.72 0.54 6.88e-27 Motion sickness; LIHC cis rs6840360 0.571 rs72730104 chr4:152543857 A/G cg22705602 chr4:152727874 NA -0.34 -6.44 -0.33 4.01e-10 Intelligence (multi-trait analysis); LIHC cis rs9378688 0.872 rs3800185 chr6:2212169 A/C cg12303981 chr6:2244766 GMDS -0.44 -5.84 -0.3 1.2e-8 Caudate nucleus volume; LIHC trans rs1552244 0.572 rs59074548 chr3:10164347 G/C cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs2228479 0.717 rs34027607 chr16:89808939 T/C cg00800038 chr16:89945340 TCF25 -0.61 -9.42 -0.45 7.08e-19 Skin colour saturation; LIHC cis rs644799 1.000 rs509720 chr11:95562771 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12893668 0.703 rs4906335 chr14:104021141 C/A cg19000871 chr14:103996768 TRMT61A -0.42 -6.83 -0.35 3.79e-11 Reticulocyte count; LIHC cis rs2574704 0.816 rs2616555 chr3:11661114 T/A cg15876825 chr3:11651881 VGLL4 0.49 7.92 0.39 3.36e-14 Body mass index; LIHC cis rs8180040 0.620 rs11720139 chr3:47036756 C/G cg16586182 chr3:47516702 SCAP 0.47 8.46 0.42 7.78e-16 Colorectal cancer; LIHC cis rs2932538 0.885 rs6693880 chr1:113110261 A/G cg22162597 chr1:113214053 CAPZA1 0.73 11.01 0.51 2.45e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs8180040 0.715 rs6772670 chr3:47191349 G/A cg27129171 chr3:47204927 SETD2 0.69 12.1 0.55 2.64e-28 Colorectal cancer; LIHC cis rs12597458 0.763 rs7195958 chr16:72036577 A/G cg01557791 chr16:72042693 DHODH 0.72 13.01 0.58 1.05e-31 Prostate cancer; LIHC cis rs769267 0.792 rs4808961 chr19:19577215 C/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.79 0.3 1.6e-8 Tonsillectomy; LIHC cis rs10744422 0.858 rs4759389 chr12:123308615 A/G cg07706471 chr12:123319906 HIP1R -0.6 -7.97 -0.4 2.4e-14 Schizophrenia; LIHC trans rs6906287 0.625 rs9320649 chr6:118693665 A/G cg11781535 chr10:38893821 NA 0.4 7.09 0.36 7.57e-12 Electrocardiographic conduction measures; LIHC cis rs734999 0.505 rs60687045 chr1:2539603 G/A cg18854424 chr1:2615690 NA 0.33 7.06 0.36 9.23e-12 Ulcerative colitis; LIHC cis rs262150 0.522 rs2527182 chr7:158813812 A/G cg19418458 chr7:158789849 NA -0.41 -6.84 -0.35 3.55e-11 Facial morphology (factor 20); LIHC trans rs7618501 0.521 rs11130222 chr3:49901060 A/T cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.61 0.34 1.45e-10 Intelligence (multi-trait analysis); LIHC cis rs4908768 0.906 rs10492966 chr1:8598005 C/T cg20416874 chr1:8611966 RERE 0.58 9.41 0.45 7.38e-19 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg08132940 chr7:1081526 C7orf50 -0.77 -6.47 -0.33 3.47e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6684514 1.000 rs2241106 chr1:156218910 C/G cg16558208 chr1:156270281 VHLL 0.51 9.03 0.44 1.26e-17 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7572733 0.534 rs700664 chr2:198671145 C/T cg10820045 chr2:198174542 NA 0.47 7.03 0.36 1.12e-11 Dermatomyositis; LIHC cis rs597539 0.615 rs583182 chr11:68678634 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 12.08 0.55 3.15e-28 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs10861342 0.892 rs11112378 chr12:105514033 A/G cg23923672 chr12:105501055 KIAA1033 0.66 7.75 0.39 1.08e-13 IgG glycosylation; LIHC cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg03806693 chr22:41940476 POLR3H -1.1 -12.96 -0.57 1.57e-31 Vitiligo; LIHC cis rs12048904 0.619 rs10783153 chr1:101328230 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 10.25 0.48 1.16e-21 Multiple sclerosis; LIHC cis rs1421811 0.630 rs72740637 chr5:32710486 G/A cg16267343 chr5:32710456 NPR3 0.65 6.56 0.33 2.03e-10 Blood pressure; LIHC cis rs4808199 0.948 rs757001 chr19:19448808 G/A cg03709012 chr19:19516395 GATAD2A 0.99 15.84 0.65 9.42e-43 Nonalcoholic fatty liver disease; LIHC cis rs10489202 1.000 rs7535138 chr1:167931462 T/G cg24449463 chr1:168025552 DCAF6 -0.53 -6.73 -0.34 7.36e-11 Schizophrenia; LIHC cis rs6089829 0.816 rs6062397 chr20:61668268 A/G cg03213289 chr20:61660250 NA 0.51 9.04 0.44 1.16e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs898097 0.841 rs4986122 chr17:80825500 C/T cg15664640 chr17:80829946 TBCD -0.74 -12.07 -0.55 3.42e-28 Breast cancer; LIHC cis rs870825 0.616 rs7694899 chr4:185625390 C/T cg04058563 chr4:185651563 MLF1IP 0.79 7.82 0.39 6.42e-14 Blood protein levels; LIHC cis rs9916302 0.731 rs11868030 chr17:37650332 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC cis rs7937890 0.684 rs12799007 chr11:14426484 T/A cg22961513 chr11:14280813 SPON1 -0.45 -6.8 -0.35 4.6e-11 Mitochondrial DNA levels; LIHC cis rs929354 0.772 rs1182364 chr7:157017912 T/C cg17757837 chr7:157058334 UBE3C -0.73 -11.97 -0.54 7.94e-28 Body mass index; LIHC cis rs919433 0.680 rs2564389 chr2:198260098 A/T cg03934865 chr2:198174659 NA 0.52 7.99 0.4 2.09e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg26831259 chr4:1366826 KIAA1530 -0.36 -5.99 -0.31 5.27e-9 Obesity-related traits; LIHC trans rs7726839 0.540 rs72705102 chr5:659437 T/C cg25482853 chr8:67687455 SGK3 0.61 6.11 0.31 2.68e-9 Obesity-related traits; LIHC cis rs8062405 0.722 rs3785354 chr16:28550667 C/T cg16576597 chr16:28551801 NUPR1 0.5 7.94 0.39 2.99e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs5769765 0.624 rs2285187 chr22:50185432 A/G cg02269571 chr22:50332266 NA -0.59 -8.01 -0.4 1.85e-14 Schizophrenia; LIHC cis rs2066819 1.000 rs11171806 chr12:56733531 A/G cg26714650 chr12:56694279 CS 1.35 13.29 0.58 8.96e-33 Psoriasis vulgaris; LIHC cis rs861020 0.677 rs12723578 chr1:210032392 G/A cg05527609 chr1:210001259 C1orf107 -0.91 -12.14 -0.55 1.97e-28 Orofacial clefts; LIHC cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.9 0.35 2.6e-11 Bipolar disorder; LIHC trans rs875971 0.545 rs73150604 chr7:65945532 T/A cg26939375 chr7:64535504 NA 0.41 6.49 0.33 2.98e-10 Aortic root size; LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg21448741 chr8:58168803 NA 0.35 6.51 0.33 2.73e-10 Developmental language disorder (linguistic errors); LIHC trans rs877282 0.945 rs71491311 chr10:791747 G/A cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs8072100 0.777 rs9914653 chr17:45537395 T/C cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.38 -6.04 -0.31 4.11e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs79387448 0.683 rs7571985 chr2:103147561 G/A cg09003973 chr2:102972529 NA 0.85 7.4 0.37 1.04e-12 Gut microbiota (bacterial taxa); LIHC cis rs11626933 1.000 rs11621007 chr14:90743967 G/A cg04374321 chr14:90722782 PSMC1 0.47 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs6840360 1.000 rs6817586 chr4:152643184 G/A cg22705602 chr4:152727874 NA -0.34 -7.3 -0.37 2.03e-12 Intelligence (multi-trait analysis); LIHC cis rs9341808 0.935 rs2322633 chr6:80845989 C/T cg08355045 chr6:80787529 NA -0.31 -5.73 -0.3 2.26e-8 Sitting height ratio; LIHC cis rs1801251 0.574 rs2250660 chr2:233752551 G/C cg25237894 chr2:233734115 C2orf82 -0.4 -7.22 -0.36 3.42e-12 Coronary artery disease; LIHC cis rs4478037 0.822 rs4528891 chr3:33121392 G/T cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.07 -0.36 9e-12 Major depressive disorder; LIHC cis rs904251 0.737 rs914347 chr6:37484970 A/C cg08126542 chr6:37504118 NA -0.4 -6.46 -0.33 3.63e-10 Cognitive performance; LIHC cis rs6963495 0.818 rs73192107 chr7:105168095 G/A cg19920283 chr7:105172520 RINT1 0.69 6.5 0.33 2.86e-10 Bipolar disorder (body mass index interaction); LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.1 -0.31 2.79e-9 Total body bone mineral density; LIHC cis rs4555082 0.794 rs2735829 chr14:105708472 C/T cg10792982 chr14:105748885 BRF1 0.48 6.31 0.32 8.84e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs7587476 0.689 rs10498025 chr2:215749256 A/G cg04004882 chr2:215674386 BARD1 0.54 7.3 0.37 2.01e-12 Neuroblastoma; LIHC cis rs9322817 0.691 rs2499659 chr6:105286124 A/T cg02098413 chr6:105308735 HACE1 0.45 8.41 0.41 1.16e-15 Thyroid stimulating hormone; LIHC cis rs903552 0.736 rs2412008 chr15:102006841 C/T cg06707286 chr15:102010195 PCSK6 -0.52 -7.42 -0.37 9.5e-13 Diabetic kidney disease; LIHC cis rs5769765 0.955 rs9616204 chr22:50303530 T/C cg09182678 chr22:50328711 NA -0.43 -6.09 -0.31 2.99e-9 Schizophrenia; LIHC cis rs2153535 0.580 rs9379206 chr6:8458021 C/A cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs7727544 0.660 rs2631361 chr5:131707380 C/A cg24060327 chr5:131705240 SLC22A5 0.6 8.64 0.42 2.25e-16 Blood metabolite levels; LIHC cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg00656387 chr3:40428638 ENTPD3 0.42 6.95 0.35 1.81e-11 Renal cell carcinoma; LIHC cis rs9457247 0.935 rs9348211 chr6:167375173 G/C cg23791538 chr6:167370224 RNASET2 0.6 9.48 0.46 4.34e-19 Crohn's disease; LIHC cis rs7959452 0.503 rs7300266 chr12:69654187 A/G cg22834771 chr12:69754056 YEATS4 -0.48 -8.39 -0.41 1.3e-15 Blood protein levels; LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg05025164 chr4:1340916 KIAA1530 0.75 11.85 0.54 2.17e-27 Longevity; LIHC cis rs10256972 0.869 rs4720158 chr7:1040325 A/G cg23978390 chr7:1156363 C7orf50 0.49 7.53 0.38 4.62e-13 Longevity;Endometriosis; LIHC cis rs9648428 0.731 rs11496028 chr7:36203759 A/G cg14708893 chr7:36124863 NA -0.65 -8.42 -0.41 1.03e-15 Obesity-related traits; LIHC cis rs2070488 0.775 rs961179 chr3:38509618 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.59 0.56 4.07e-30 Electrocardiographic conduction measures; LIHC cis rs754466 0.580 rs2289311 chr10:79565655 G/A cg17075019 chr10:79541650 NA -0.75 -11.43 -0.53 7.65e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs853679 0.517 rs9380061 chr6:28132803 T/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.59 0.5 7.49e-23 Vitiligo; LIHC trans rs11039798 0.588 rs11039782 chr11:48524785 A/G cg15704280 chr7:45808275 SEPT13 0.57 6.32 0.32 8.19e-10 Axial length; LIHC cis rs739401 0.611 rs12284275 chr11:3024384 T/C cg05729581 chr11:3078854 CARS -0.45 -6.26 -0.32 1.15e-9 Longevity; LIHC cis rs60871478 0.945 rs62432254 chr7:804175 C/T cg13844804 chr7:814759 HEATR2 0.44 5.95 0.31 6.72e-9 Cerebrospinal P-tau181p levels; LIHC trans rs3749237 1.000 rs11920900 chr3:49823024 G/C cg21665057 chr3:196295764 WDR53;FBXO45 0.67 10.37 0.49 4.17e-22 Resting heart rate; LIHC cis rs9911578 0.874 rs302874 chr17:56767996 A/G cg05425664 chr17:57184151 TRIM37 -0.55 -8.12 -0.4 8.43e-15 Intelligence (multi-trait analysis); LIHC cis rs10426930 0.844 rs56386046 chr19:5037230 C/T cg18473234 chr19:5097819 KDM4B 0.54 6.79 0.34 5.11e-11 Monocyte percentage of white cells; LIHC cis rs12048904 0.541 rs6699536 chr1:101276544 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.44 6.47 0.33 3.33e-10 Multiple sclerosis; LIHC cis rs7799006 0.527 rs73039284 chr7:2221583 C/G cg02951883 chr7:2050386 MAD1L1 -0.48 -7.54 -0.38 4.27e-13 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6938 0.575 rs12909335 chr15:75214789 T/G cg14664628 chr15:75095509 CSK -0.46 -5.78 -0.3 1.7e-8 Breast cancer; LIHC cis rs10845606 0.581 rs11055015 chr12:12836679 T/G cg04607235 chr12:12878440 APOLD1 -0.46 -6.35 -0.32 6.88e-10 Systemic lupus erythematosus; LIHC cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg18357526 chr6:26021779 HIST1H4A 0.83 11.45 0.53 6.63e-26 Intelligence (multi-trait analysis); LIHC cis rs6942756 0.876 rs57263220 chr7:129010858 C/A cg02491457 chr7:128862824 NA -0.59 -8.82 -0.43 6.01e-17 White matter hyperintensity burden; LIHC cis rs6840360 1.000 rs751014 chr4:152601902 G/A cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.42e-10 Intelligence (multi-trait analysis); LIHC cis rs9399137 0.507 rs4895437 chr6:135317354 G/A cg24558204 chr6:135376177 HBS1L 0.61 10.4 0.49 3.53e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs2760061 0.583 rs708123 chr1:228220495 A/G cg01200585 chr1:228362443 C1orf69 0.58 8.61 0.42 2.79e-16 Diastolic blood pressure; LIHC trans rs208520 0.690 rs12209753 chr6:66703951 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.74 8.52 0.42 5.1e-16 Exhaled nitric oxide output; LIHC cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg03060546 chr3:49711283 APEH 0.41 6.14 0.32 2.24e-9 Menarche (age at onset); LIHC cis rs763014 0.966 rs12935215 chr16:670605 T/C cg04709771 chr16:646395 RAB40C 0.47 8.33 0.41 1.99e-15 Height; LIHC cis rs2239547 0.563 rs9876403 chr3:52916916 C/T cg11645453 chr3:52864694 ITIH4 0.33 8.6 0.42 2.86e-16 Schizophrenia; LIHC trans rs11148252 0.755 rs116860555 chr13:52936937 C/T cg18335740 chr13:41363409 SLC25A15 -0.37 -6.47 -0.33 3.46e-10 Lewy body disease; LIHC cis rs881375 0.933 rs10818485 chr9:123667816 G/C cg14580859 chr9:123691850 NA 0.39 6.83 0.35 3.96e-11 Rheumatoid arthritis; LIHC cis rs11955398 0.521 rs4298206 chr5:60012235 T/C cg02684056 chr5:59996105 DEPDC1B -0.41 -5.79 -0.3 1.63e-8 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.887 rs28699126 chr2:26357294 C/T cg27170947 chr2:26402098 FAM59B -0.63 -7.99 -0.4 2.08e-14 Gut microbiome composition (summer); LIHC cis rs3015497 0.904 rs3015501 chr14:51108524 C/T cg09863266 chr14:51125203 SAV1 -0.39 -6.34 -0.32 7.3e-10 Mean platelet volume; LIHC cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg23205692 chr1:25664452 TMEM50A -0.37 -6.01 -0.31 4.67e-9 Erythrocyte sedimentation rate; LIHC cis rs1633360 1 rs1633360 chr12:58108052 C/T cg15848620 chr12:58087721 OS9 -0.43 -5.92 -0.31 7.69e-9 Rheumatoid arthritis; LIHC cis rs796364 1.000 rs281760 chr2:200787804 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.11 0.44 6.98e-18 Schizophrenia; LIHC cis rs35110281 0.667 rs2250773 chr21:45087786 T/C cg21573476 chr21:45109991 RRP1B -0.58 -11.11 -0.51 1.13e-24 Mean corpuscular volume; LIHC trans rs1814175 0.645 rs7123448 chr11:49764865 T/G cg15704280 chr7:45808275 SEPT13 -0.95 -19.65 -0.73 4.32e-58 Height; LIHC cis rs864537 0.618 rs2988277 chr1:167431352 A/G cg22356347 chr1:167427500 CD247 0.39 6.43 0.33 4.4e-10 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs10871290 1.000 rs11149710 chr16:74472546 G/T cg01733217 chr16:74700730 RFWD3 -0.41 -6.91 -0.35 2.33e-11 Breast cancer; LIHC cis rs9303280 0.806 rs36095411 chr17:38031865 T/G cg11212589 chr17:38028394 ZPBP2 0.35 7.16 0.36 4.95e-12 Self-reported allergy; LIHC cis rs6138458 0.961 rs227625 chr20:24911618 T/C cg26195577 chr20:24973756 C20orf3 1.13 14.83 0.63 9.14e-39 Blood protein levels; LIHC cis rs9916302 0.904 rs620686 chr17:37453617 A/G cg00129232 chr17:37814104 STARD3 0.39 6.25 0.32 1.23e-9 Glomerular filtration rate (creatinine); LIHC cis rs7635838 0.819 rs2454481 chr3:11535178 C/T cg00170343 chr3:11313890 ATG7 0.4 6.19 0.32 1.67e-9 HDL cholesterol; LIHC cis rs1577917 0.958 rs2324817 chr6:86462654 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.47 -0.42 7.18e-16 Response to antipsychotic treatment; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg24129382 chr3:119529158 NR1I2 -0.22 -6.22 -0.32 1.49e-9 Pain; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11642254 chr7:156684974 LMBR1 0.48 6.98 0.35 1.52e-11 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02315113 chr1:173684045 KLHL20 0.41 6.41 0.33 4.71e-10 Cognitive function; LIHC cis rs7224685 0.501 rs2054038 chr17:4014391 A/C cg09695851 chr17:3907499 NA 0.67 11.13 0.52 8.99e-25 Type 2 diabetes; LIHC cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.28e-9 Menopause (age at onset); LIHC cis rs6952808 0.501 rs3778999 chr7:2180885 G/A cg04267008 chr7:1944627 MAD1L1 -0.49 -7.63 -0.38 2.38e-13 Bipolar disorder and schizophrenia; LIHC cis rs2072499 0.833 rs2251636 chr1:156202809 G/C cg25208724 chr1:156163844 SLC25A44 0.59 10.14 0.48 2.61e-21 Testicular germ cell tumor; LIHC cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg21448741 chr8:58168803 NA 0.38 6.23 0.32 1.35e-9 Developmental language disorder (linguistic errors); LIHC cis rs7249142 0.562 rs10854009 chr19:19284705 A/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.47 -7.88 -0.39 4.53e-14 IgG glycosylation; LIHC cis rs12611088 0.571 rs2599447 chr19:44007012 G/A cg13740135 chr19:44006432 PHLDB3 -0.42 -6.38 -0.33 5.61e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs735860 0.726 rs209507 chr6:53194768 T/A cg10236188 chr6:53219634 NA 0.41 7.41 0.37 1.01e-12 Glaucoma; LIHC cis rs7937890 0.559 rs2597221 chr11:14527075 C/T cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs9513627 0.573 rs7325697 chr13:100117793 A/G cg25919922 chr13:100150906 NA 0.75 8.44 0.42 9.31e-16 Obesity-related traits; LIHC cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg25364880 chr3:44379878 C3orf23 0.59 8.1 0.4 9.87e-15 Depressive symptoms; LIHC trans rs7615952 0.799 rs13315434 chr3:125641394 T/G cg07211511 chr3:129823064 LOC729375 -0.84 -10.68 -0.5 3.74e-23 Blood pressure (smoking interaction); LIHC cis rs67981189 0.593 rs2240341 chr14:71373580 T/C cg15816911 chr14:71606274 NA -0.41 -6.51 -0.33 2.6200000000000003e-10 Schizophrenia; LIHC cis rs8014204 0.819 rs2003490 chr14:75377555 C/A cg08847533 chr14:75593920 NEK9 0.4 6.67 0.34 1.03e-10 Caffeine consumption; LIHC cis rs9911578 0.967 rs7502208 chr17:57165097 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -9.0 -0.44 1.59e-17 Intelligence (multi-trait analysis); LIHC cis rs11608355 0.515 rs4766476 chr12:109934700 A/G cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg01171360 chr6:293285 DUSP22 -0.46 -6.86 -0.35 3.28e-11 Menopause (age at onset); LIHC trans rs208520 0.837 rs208489 chr6:66927584 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.24 -0.41 3.72e-15 Exhaled nitric oxide output; LIHC cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg18252515 chr7:66147081 NA -1.3 -16.67 -0.67 4.52e-46 Diabetic kidney disease; LIHC cis rs3736485 0.932 rs4774592 chr15:51778879 C/T cg08986416 chr15:51914746 DMXL2 -0.4 -6.05 -0.31 3.78e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs17666538 0.585 rs1669733 chr8:606696 C/T cg23958373 chr8:599963 NA -0.75 -6.19 -0.32 1.69e-9 IgG glycosylation; LIHC cis rs801193 0.844 rs7779971 chr7:66161790 T/C cg11764359 chr7:65958608 NA 0.71 10.55 0.5 1.02e-22 Aortic root size; LIHC trans rs9951602 0.512 rs3859325 chr18:76652175 A/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.58 0.5 8.16e-23 Obesity-related traits; LIHC cis rs858239 0.539 rs2141306 chr7:23191664 G/A cg23682824 chr7:23144976 KLHL7 0.46 6.83 0.35 3.89e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs17125944 0.686 rs7155860 chr14:53335229 G/C cg00686598 chr14:53173677 PSMC6 -0.74 -8.52 -0.42 5.34e-16 Alzheimer's disease (late onset); LIHC cis rs317689 0.581 rs315132 chr12:69761996 G/C cg22834771 chr12:69754056 YEATS4 -0.47 -8.0 -0.4 1.95e-14 Response to diuretic therapy; LIHC cis rs807669 0.504 rs8141941 chr22:19166263 G/A cg02655711 chr22:19163373 SLC25A1 0.34 5.84 0.3 1.2e-8 Metabolite levels; LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.26 0.75 1.62e-64 Height; LIHC cis rs7106204 0.748 rs4636667 chr11:24238615 T/C ch.11.24196551F chr11:24239977 NA 0.8 11.22 0.52 4.32e-25 Response to Homoharringtonine (cytotoxicity); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg21408716 chr3:52279700 PPM1M -0.46 -6.16 -0.32 2.01e-9 Hepatitis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18827097 chr2:3522506 ADI1 0.41 6.59 0.34 1.65e-10 Cognitive function; LIHC cis rs597539 0.654 rs655816 chr11:68626405 A/G cg04772025 chr11:68637568 NA 0.45 6.1 0.31 2.91e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg24947615 chr21:44515479 U2AF1 0.41 6.08 0.31 3.28e-9 Alopecia areata; LIHC cis rs4819052 0.851 rs2838848 chr21:46671017 A/G cg22633049 chr21:46681294 NA -0.37 -6.34 -0.32 7.23e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9549367 0.789 rs2025247 chr13:113882564 C/G cg00898013 chr13:113819073 PROZ -0.43 -7.49 -0.38 5.86e-13 Platelet distribution width; LIHC cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg08499158 chr17:42289980 UBTF -0.49 -8.1 -0.4 9.85e-15 Total body bone mineral density; LIHC cis rs10876993 0.928 rs2640631 chr12:58067532 A/T cg18357645 chr12:58087776 OS9 0.49 8.16 0.4 6.68e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs8062405 0.895 rs56186137 chr16:28825953 A/G cg07451762 chr16:28383216 NA 0.34 6.47 0.33 3.31e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11252926 0.673 rs816620 chr10:645916 A/G cg09445902 chr10:555545 DIP2C 0.36 5.75 0.3 1.96e-8 Psychosis in Alzheimer's disease; LIHC cis rs66573146 0.831 rs56320732 chr4:6974319 G/A cg15105060 chr4:7024189 TBC1D14 -0.71 -6.02 -0.31 4.41e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6430585 0.583 rs73957037 chr2:136588031 C/A cg25344623 chr2:136566232 LCT -0.34 -5.92 -0.3 7.92e-9 Corneal structure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00116058 chr5:154320652 MRPL22 0.43 6.08 0.31 3.16e-9 Lung function (FEV1/FVC); LIHC cis rs4819052 1.000 rs13053002 chr21:46677854 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 10.35 0.49 4.97e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs950169 0.649 rs12911612 chr15:84691014 T/C cg17507749 chr15:85114479 UBE2QP1 0.67 6.39 0.33 5.38e-10 Schizophrenia; LIHC cis rs546131 0.642 rs473848 chr11:34851977 A/C cg06937548 chr11:34938143 PDHX;APIP 0.57 7.45 0.37 7.55e-13 Lung disease severity in cystic fibrosis; LIHC cis rs9942416 0.601 rs114547168 chr5:74991903 A/G cg19683494 chr5:74908142 NA 0.54 7.16 0.36 5.12e-12 Age-related disease endophenotypes; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg23933339 chr15:57731055 CGNL1 0.56 6.6 0.34 1.54e-10 Mean platelet volume; LIHC cis rs765787 0.530 rs1648286 chr15:45517386 G/C cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg18306943 chr3:40428807 ENTPD3 0.41 7.12 0.36 6.48e-12 Renal cell carcinoma; LIHC cis rs6089584 0.546 rs6089308 chr20:60583529 C/T cg06108461 chr20:60628389 TAF4 -0.53 -7.18 -0.36 4.31e-12 Body mass index; LIHC cis rs743757 1.000 rs743857 chr3:50493550 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.49 7.73 0.39 1.25e-13 Diastolic blood pressure; LIHC cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg13047869 chr3:10149882 C3orf24 0.51 6.66 0.34 1.13e-10 Alzheimer's disease; LIHC cis rs10870270 0.913 rs4550 chr10:133781798 C/T cg17892150 chr10:133769511 PPP2R2D -0.68 -12.89 -0.57 2.93e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9902453 0.967 rs8067576 chr17:28444254 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.62 9.69 0.46 9.11e-20 Coffee consumption (cups per day); LIHC cis rs2842992 0.915 rs2842980 chr6:160100116 A/T cg11366901 chr6:160182831 ACAT2 0.9 14.0 0.6 1.66e-35 Age-related macular degeneration (geographic atrophy); LIHC cis rs2180341 0.960 rs1543432 chr6:127698018 T/C cg27446573 chr6:127587934 RNF146 1.03 16.24 0.66 2.33e-44 Breast cancer; LIHC cis rs2439831 1.000 rs2254321 chr15:43707542 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.1 0.58 4.59e-32 Lung cancer in ever smokers; LIHC cis rs3809566 0.963 rs4775608 chr15:63331940 A/G cg12160578 chr15:63334699 TPM1 -0.6 -8.66 -0.42 1.93e-16 Platelet count; LIHC cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg08499158 chr17:42289980 UBTF -0.52 -9.04 -0.44 1.16e-17 Total body bone mineral density; LIHC cis rs12451471 0.500 rs8077056 chr17:78076006 C/T cg06718696 chr17:78121285 EIF4A3 0.89 10.12 0.48 3.02e-21 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs2180341 0.920 rs1073932 chr6:127682009 G/T cg24812749 chr6:127587940 RNF146 1.04 15.21 0.64 3.01e-40 Breast cancer; LIHC cis rs35883536 0.647 rs2809790 chr1:101040461 C/T cg14515779 chr1:101123966 NA -0.45 -6.38 -0.33 5.67e-10 Monocyte count; LIHC cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg16049864 chr8:95962084 TP53INP1 -0.63 -11.87 -0.54 1.88e-27 Type 2 diabetes; LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg18279126 chr7:2041391 MAD1L1 -0.36 -6.0 -0.31 4.9e-9 Bipolar disorder and schizophrenia; LIHC cis rs10464366 0.544 rs4540324 chr7:39185299 G/C cg15212455 chr7:39170539 POU6F2 0.47 8.45 0.42 8.36e-16 IgG glycosylation; LIHC cis rs7582180 0.590 rs11123828 chr2:100960918 T/G cg14675211 chr2:100938903 LONRF2 0.54 8.06 0.4 1.27e-14 Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14379462 chr9:136234288 SURF4 0.46 6.1 0.31 2.83e-9 Systolic blood pressure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04015759 chr2:27718181 FNDC4 0.39 6.27 0.32 1.1e-9 Lung function (FEV1/FVC); LIHC cis rs58785573 0.504 rs9522 chr4:38666972 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.57 8.05 0.4 1.34e-14 Lymphocyte percentage of white cells; LIHC cis rs4970988 0.556 rs6681426 chr1:150586971 G/A cg15448220 chr1:150897856 SETDB1 -0.43 -6.63 -0.34 1.33e-10 Urate levels; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs2075165 0.836 rs7512751 chr1:156234439 T/G cg20302342 chr1:156215951 PAQR6 0.35 6.69 0.34 8.99e-11 Tonsillectomy; LIHC trans rs11039798 0.582 rs1304193 chr11:48688588 C/T cg15704280 chr7:45808275 SEPT13 0.61 6.99 0.35 1.44e-11 Axial length; LIHC cis rs10870270 0.830 rs10781571 chr10:133774316 G/C cg17892150 chr10:133769511 PPP2R2D -0.66 -12.09 -0.55 2.85e-28 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10832963 1.000 rs11024739 chr11:18645843 A/C cg20219074 chr11:18656078 SPTY2D1 -0.84 -13.87 -0.6 4.92e-35 Breast cancer; LIHC cis rs17106184 0.892 rs17106175 chr1:50904241 G/A cg07174182 chr1:51127561 FAF1 -0.62 -6.88 -0.35 2.88e-11 Type 2 diabetes; LIHC cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg06238570 chr21:40685208 BRWD1 0.61 7.28 0.37 2.36e-12 Cognitive function; LIHC cis rs2576037 0.526 rs2571024 chr18:44557877 G/T cg19077165 chr18:44547161 KATNAL2 0.43 6.49 0.33 3.09e-10 Personality dimensions; LIHC cis rs2574704 0.701 rs1561073 chr3:11642114 T/A cg15876825 chr3:11651881 VGLL4 -0.47 -6.99 -0.35 1.47e-11 Body mass index; LIHC cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg21226059 chr5:178986404 RUFY1 -0.37 -5.72 -0.3 2.29e-8 Lung cancer; LIHC cis rs2302190 0.882 rs8072873 chr17:56669049 G/C cg05425664 chr17:57184151 TRIM37 -0.47 -5.89 -0.3 9.43e-9 Vitamin D levels; LIHC cis rs10089 1.000 rs3816006 chr5:127450581 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.03e-11 Ileal carcinoids; LIHC cis rs4925386 0.765 rs6142737 chr20:60919800 C/G cg06026331 chr20:60912101 LAMA5 0.63 9.39 0.45 8.71e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7027203 0.828 rs10761287 chr9:96609150 A/G cg14396892 chr9:96623032 NA -0.33 -6.3 -0.32 9.26e-10 DNA methylation (variation); LIHC cis rs6121246 0.909 rs6060644 chr20:30265652 G/A cg13852791 chr20:30311386 BCL2L1 0.97 9.8 0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg22963979 chr7:1858916 MAD1L1 -0.46 -7.65 -0.38 2.08e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs8017423 0.967 rs8009493 chr14:90690083 G/C cg04374321 chr14:90722782 PSMC1 0.72 13.55 0.59 8.78e-34 Mortality in heart failure; LIHC cis rs11229555 0.645 rs12294062 chr11:58175603 G/T cg15696309 chr11:58395628 NA -0.63 -7.49 -0.38 5.92e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs1459104 0.636 rs559362 chr11:55275456 T/G cg15704280 chr7:45808275 SEPT13 0.7 7.16 0.36 5.01e-12 Body mass index; LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg13126279 chr21:47581558 C21orf56 -0.46 -7.22 -0.36 3.35e-12 Testicular germ cell tumor; LIHC cis rs12744310 0.830 rs4406620 chr1:41792765 A/G cg03962019 chr1:41807865 NA 0.39 6.38 0.33 5.89e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11190604 0.767 rs10883484 chr10:102174803 G/C cg07080220 chr10:102295463 HIF1AN 0.45 6.15 0.32 2.12e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10193935 0.786 rs13399052 chr2:42385151 G/A cg27598129 chr2:42591480 NA -0.74 -11.56 -0.53 2.59e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2404602 0.735 rs2048856 chr15:76800083 C/T cg23625390 chr15:77176239 SCAPER -0.46 -7.6 -0.38 2.79e-13 Blood metabolite levels; LIHC trans rs561341 0.941 rs17780080 chr17:30343146 G/A cg20587970 chr11:113659929 NA -1.45 -12.12 -0.55 2.26e-28 Hip circumference adjusted for BMI; LIHC cis rs34172651 0.537 rs8049014 chr16:24698903 A/G cg00339695 chr16:24857497 SLC5A11 0.48 7.38 0.37 1.19e-12 Intelligence (multi-trait analysis); LIHC cis rs4853012 0.793 rs6723185 chr2:74344884 T/A cg20011983 chr2:74347215 NA -0.39 -5.83 -0.3 1.31e-8 Gestational age at birth (maternal effect); LIHC cis rs2380220 0.510 rs9387562 chr6:96057006 G/T cg04719120 chr6:96025338 MANEA 0.6 7.15 0.36 5.22e-12 Behavioural disinhibition (generation interaction); LIHC cis rs6690583 0.623 rs12047435 chr1:85452927 T/G cg22153463 chr1:85462885 MCOLN2 0.52 6.26 0.32 1.16e-9 Serum sulfate level; LIHC cis rs963731 0.737 rs6544197 chr2:39315388 T/C cg04010122 chr2:39346883 SOS1 -0.68 -6.03 -0.31 4.15e-9 Corticobasal degeneration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23250374 chr4:57253573 AASDH -0.5 -6.05 -0.31 3.84e-9 Systolic blood pressure; LIHC cis rs7572733 0.534 rs1518361 chr2:198812874 A/G cg03934865 chr2:198174659 NA 0.48 6.96 0.35 1.78e-11 Dermatomyositis; LIHC cis rs796364 1.000 rs11680723 chr2:200810957 C/G cg23649088 chr2:200775458 C2orf69 -0.57 -5.87 -0.3 1.02e-8 Schizophrenia; LIHC cis rs3849570 0.961 rs3772896 chr3:81751968 C/T cg07356753 chr3:81810745 GBE1 -0.61 -10.07 -0.48 4.75e-21 Waist circumference;Body mass index; LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg06558623 chr16:89946397 TCF25 0.87 13.12 0.58 3.91e-32 Skin colour saturation; LIHC cis rs10489202 0.583 rs201539 chr1:167995407 A/G cg24449463 chr1:168025552 DCAF6 -0.64 -9.84 -0.47 2.89e-20 Schizophrenia; LIHC cis rs1005277 0.579 rs2504140 chr10:38387579 T/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC trans rs11039798 0.623 rs6485879 chr11:48587984 G/T cg15704280 chr7:45808275 SEPT13 0.58 6.47 0.33 3.44e-10 Axial length; LIHC cis rs965469 1.000 rs6037590 chr20:3374085 G/A cg25506879 chr20:3388711 C20orf194 -0.58 -6.63 -0.34 1.3e-10 IFN-related cytopenia; LIHC cis rs9325144 0.555 rs2387855 chr12:38687964 T/G cg26384229 chr12:38710491 ALG10B 0.6 8.43 0.41 9.62e-16 Morning vs. evening chronotype; LIHC cis rs1552244 0.882 rs6443279 chr3:10053599 C/A cg00149659 chr3:10157352 C3orf10 0.54 6.07 0.31 3.45e-9 Alzheimer's disease; LIHC cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg27297192 chr10:134578999 INPP5A 0.54 7.87 0.39 4.76e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11030122 0.673 rs10835601 chr11:4106416 G/A cg18678763 chr11:4115507 RRM1 -0.59 -8.63 -0.42 2.4e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs34540877 1.000 rs35413309 chr19:33167837 C/T cg22980127 chr19:33182716 NUDT19 0.97 6.06 0.31 3.68e-9 Red cell distribution width; LIHC cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg10862848 chr6:42927986 GNMT -0.26 -6.2 -0.32 1.62e-9 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs17685 0.702 rs6960598 chr7:75772991 T/C cg19862616 chr7:65841803 NCRNA00174 0.78 14.69 0.62 3.25e-38 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8067545 0.611 rs11653869 chr17:20197586 T/G cg13482628 chr17:19912719 NA -0.41 -6.77 -0.34 5.62e-11 Schizophrenia; LIHC cis rs1198430 1.000 rs1198431 chr1:23755716 C/T cg13183780 chr1:23809682 ASAP3 0.55 8.1 0.4 9.75e-15 Total cholesterol levels; LIHC cis rs910316 0.737 rs175084 chr14:75519175 C/T cg11812906 chr14:75593930 NEK9 -0.75 -13.88 -0.6 4.5e-35 Height; LIHC cis rs860295 0.580 rs12032720 chr1:155274960 G/C cg02153340 chr1:155202674 NA -0.35 -6.16 -0.32 2.08e-9 Body mass index; LIHC cis rs6570726 0.935 rs385134 chr6:145851005 C/T cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs4908768 0.906 rs55830087 chr1:8681550 C/T cg25722041 chr1:8623473 RERE 0.43 5.75 0.3 2.01e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6088580 0.601 rs6059827 chr20:33016358 C/T cg08999081 chr20:33150536 PIGU 0.66 13.22 0.58 1.58e-32 Glomerular filtration rate (creatinine); LIHC cis rs2463822 0.687 rs118012228 chr11:62155914 G/A cg06239285 chr11:62104954 ASRGL1 -0.97 -6.62 -0.34 1.39e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs11690935 0.838 rs10432423 chr2:172753295 G/A cg13550731 chr2:172543902 DYNC1I2 -0.49 -8.13 -0.4 7.91e-15 Schizophrenia; LIHC trans rs8012283 0.591 rs72683631 chr14:51261114 C/A cg07338119 chr7:157211683 NA -0.67 -6.08 -0.31 3.2e-9 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs4660306 0.614 rs1007859 chr1:45911906 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.66 6.86 0.35 3.31e-11 Homocysteine levels; LIHC cis rs7914558 0.966 rs11191518 chr10:104782853 C/G cg04362960 chr10:104952993 NT5C2 0.38 5.75 0.3 1.98e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2386661 0.736 rs11818357 chr10:5661667 C/T cg17085576 chr10:5658249 NA -0.36 -6.44 -0.33 4.05e-10 Breast cancer; LIHC cis rs12701220 0.655 rs7784403 chr7:1153077 G/A cg16145915 chr7:1198662 ZFAND2A -0.35 -6.87 -0.35 2.97e-11 Bronchopulmonary dysplasia; LIHC cis rs2439831 0.702 rs7175032 chr15:44060236 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.42 0.41 1.09e-15 Lung cancer in ever smokers; LIHC cis rs5167 0.566 rs204905 chr19:45460764 G/A cg09555818 chr19:45449301 APOC2 0.23 6.57 0.33 1.87e-10 Blood protein levels; LIHC cis rs61990749 0.597 rs8016447 chr14:78222068 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.6 9.98 0.47 9.71e-21 Fibroblast growth factor basic levels; LIHC cis rs875971 0.862 rs35034167 chr7:65580166 C/G cg18252515 chr7:66147081 NA 0.43 5.98 0.31 5.63e-9 Aortic root size; LIHC cis rs4589502 0.800 rs2035150 chr15:67201794 A/C cg12317470 chr15:67143691 NA -0.6 -7.32 -0.37 1.77e-12 Lung cancer (smoking interaction); LIHC cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.66 -0.46 1.13e-19 Bipolar disorder; LIHC cis rs13217239 0.646 rs12209886 chr6:26984757 G/A cg18867708 chr6:26865862 GUSBL1 0.52 8.1 0.4 9.8e-15 Schizophrenia; LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg00149659 chr3:10157352 C3orf10 0.68 6.93 0.35 2.11e-11 Alzheimer's disease; LIHC cis rs3768617 0.510 rs7542640 chr1:183063738 G/A ch.1.3577855R chr1:183094577 LAMC1 0.63 10.94 0.51 4.35e-24 Fuchs's corneal dystrophy; LIHC cis rs6964587 1.000 rs35653487 chr7:91745441 C/G cg17063962 chr7:91808500 NA 1.02 19.7 0.73 2.9e-58 Breast cancer; LIHC cis rs1790761 0.632 rs625978 chr11:67344664 C/T cg21734168 chr11:67353974 GSTP1 -0.28 -6.78 -0.34 5.17e-11 Mean corpuscular volume; LIHC cis rs17685 0.672 rs10952841 chr7:75778626 A/C cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1348850 0.567 rs7605493 chr2:178534983 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.62 0.38 2.46e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1559088 0.948 rs10408093 chr19:33597816 T/C cg27124370 chr19:33622961 WDR88 0.52 8.21 0.41 4.63e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4517514 0.509 rs10830434 chr11:89912652 T/C cg05041596 chr11:89867385 NAALAD2 0.42 6.77 0.34 5.49e-11 Trans fatty acid levels; LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 23.22 0.78 2.96e-72 Prudent dietary pattern; LIHC cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg24642844 chr7:1081250 C7orf50 -0.6 -6.53 -0.33 2.37e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07327967 chr16:87926682 CA5A 0.4 6.13 0.31 2.38e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10751667 0.643 rs10902244 chr11:949981 A/G ch.11.42038R chr11:967971 AP2A2 0.55 9.83 0.47 3.11e-20 Alzheimer's disease (late onset); LIHC trans rs12496230 0.953 rs12494775 chr3:66874105 A/G cg16290275 chr1:208042910 NA -0.53 -6.09 -0.31 3.08e-9 Type 2 diabetes; LIHC cis rs11671005 0.735 rs12981875 chr19:58935130 A/C cg25952890 chr19:58913133 NA 0.68 7.26 0.37 2.62e-12 Mean platelet volume; LIHC cis rs2282802 0.677 rs9686454 chr5:139627813 T/C cg26211634 chr5:139558579 C5orf32 0.4 6.18 0.32 1.87e-9 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs709400 0.628 rs7150317 chr14:103921691 C/G cg26031613 chr14:104095156 KLC1 0.72 9.71 0.46 7.42e-20 Body mass index; LIHC cis rs9486719 1.000 rs11757063 chr6:96884886 C/T cg06623918 chr6:96969491 KIAA0776 -0.66 -6.86 -0.35 3.27e-11 Migraine;Coronary artery disease; LIHC cis rs8103278 1.000 rs7258283 chr19:46335511 C/T cg14061069 chr19:46274453 DMPK -0.56 -8.55 -0.42 4.11e-16 Coronary artery disease; LIHC cis rs597539 0.615 rs629426 chr11:68671104 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.15 0.52 8.09e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14416316 chr13:111145583 COL4A2 0.4 7.35 0.37 1.44e-12 Cognitive function; LIHC cis rs7937890 0.874 rs2303972 chr11:14303282 T/A cg02886208 chr11:14281011 SPON1 0.63 9.21 0.45 3.48e-18 Mitochondrial DNA levels; LIHC cis rs265548 0.646 rs36692 chr19:17906839 C/T cg16024904 chr19:17905718 B3GNT3 0.44 6.25 0.32 1.25e-9 Tumor biomarkers; LIHC cis rs2404602 0.684 rs10851888 chr15:76902506 C/T cg23625390 chr15:77176239 SCAPER -0.53 -8.7 -0.43 1.43e-16 Blood metabolite levels; LIHC cis rs7249142 0.549 rs12975253 chr19:19279745 A/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.34 -5.82 -0.3 1.38e-8 IgG glycosylation; LIHC cis rs11190604 1.000 rs11190558 chr10:102209397 C/A cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1577917 0.771 rs12205013 chr6:86333029 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.38 -0.56 2.37e-29 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg07424592 chr7:64974309 NA 0.84 9.58 0.46 2.05e-19 Diabetic kidney disease; LIHC cis rs11690935 0.549 rs62183819 chr2:172904520 G/T cg13550731 chr2:172543902 DYNC1I2 0.47 6.92 0.35 2.27e-11 Schizophrenia; LIHC cis rs7917772 0.636 rs2486757 chr10:104535145 C/T cg22532475 chr10:104410764 TRIM8 -0.35 -6.31 -0.32 8.56e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs34779708 0.966 rs4934538 chr10:35472150 T/C cg03585969 chr10:35415529 CREM 0.87 13.09 0.58 4.92e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9303401 0.614 rs3803753 chr17:56540110 G/A cg25039879 chr17:56429692 SUPT4H1 0.75 8.41 0.41 1.1e-15 Cognitive test performance; LIHC cis rs35306767 0.903 rs765867 chr10:869901 G/T cg20503657 chr10:835505 NA 1.03 11.77 0.54 4.55e-27 Eosinophil percentage of granulocytes; LIHC cis rs9814567 1.000 rs4955555 chr3:134286427 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9486719 1.000 rs2064947 chr6:97052754 C/T cg06623918 chr6:96969491 KIAA0776 -0.63 -6.5 -0.33 2.83e-10 Migraine;Coronary artery disease; LIHC cis rs1707322 0.964 rs1707339 chr1:46513179 A/G cg03146154 chr1:46216737 IPP -0.44 -7.16 -0.36 4.84e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1577917 0.771 rs4145082 chr6:86352016 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -8.2 -0.41 4.88e-15 Response to antipsychotic treatment; LIHC cis rs11233413 0.508 rs10792666 chr11:82650000 A/T cg24227371 chr11:82718527 RAB30 -0.29 -6.51 -0.33 2.6200000000000003e-10 Economic and political preferences (feminism/equality); LIHC cis rs1800469 1.000 rs2241712 chr19:41869756 C/T cg08477640 chr19:41863820 B9D2 0.35 5.76 0.3 1.9e-8 Colorectal cancer; LIHC cis rs10792665 0.510 rs7116170 chr11:82630702 G/A cg24227371 chr11:82718527 RAB30 -0.28 -6.59 -0.34 1.66e-10 Obesity-related traits; LIHC cis rs6920364 1 rs6920364 chr6:167376466 G/C cg23791538 chr6:167370224 RNASET2 0.6 9.48 0.46 4.34e-19 Lung cancer; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg14257396 chr1:107603778 NA -0.37 -6.15 -0.32 2.17e-9 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22719782 chr11:114310057 REXO2 0.52 6.52 0.33 2.59e-10 Lung function (FEV1/FVC); LIHC cis rs2153535 0.580 rs2184585 chr6:8474168 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg15320075 chr8:145703422 NA -0.66 -12.67 -0.57 2.05e-30 Age at first birth; LIHC cis rs11229555 0.874 rs10896788 chr11:58292976 G/A cg15696309 chr11:58395628 NA -0.73 -9.0 -0.44 1.64e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7264396 0.561 rs6060741 chr20:34571484 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.49 8.29 0.41 2.6e-15 Total cholesterol levels; LIHC cis rs1707322 1.000 rs1768817 chr1:46514534 C/G cg03146154 chr1:46216737 IPP -0.44 -7.16 -0.36 4.84e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7107174 1.000 rs11237469 chr11:78072875 A/T cg02023728 chr11:77925099 USP35 0.46 8.81 0.43 6.43e-17 Testicular germ cell tumor; LIHC cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.68 0.46 9.69e-20 Bipolar disorder; LIHC cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg03517284 chr6:25882590 NA -0.39 -6.06 -0.31 3.56e-9 Height; LIHC cis rs8062405 0.723 rs4788079 chr16:28559363 C/A cg07451762 chr16:28383216 NA 0.39 7.08 0.36 8.46e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3824867 1.000 rs3824867 chr11:47468569 A/G cg20307385 chr11:47447363 PSMC3 0.6 8.18 0.4 5.74e-15 Mean corpuscular hemoglobin; LIHC cis rs80282103 0.618 rs74117848 chr10:1160974 T/G cg08668510 chr10:1095578 IDI1 0.64 6.13 0.31 2.37e-9 Glomerular filtration rate (creatinine); LIHC cis rs12493885 0.725 rs11718315 chr3:153724197 A/G cg10247383 chr3:153839028 SGEF 0.65 6.1 0.31 2.89e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs7980799 0.682 rs4931719 chr12:33602986 G/A cg26384229 chr12:38710491 ALG10B -0.45 -6.06 -0.31 3.52e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg08219700 chr8:58056026 NA 0.5 6.31 0.32 8.65e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27498675 chr19:41945691 ATP5SL 0.4 6.05 0.31 3.79e-9 Cognitive function; LIHC cis rs7613875 0.620 rs7624030 chr3:50071279 A/C cg24110177 chr3:50126178 RBM5 0.54 8.82 0.43 6e-17 Body mass index; LIHC cis rs6461049 0.765 rs10224497 chr7:2149967 A/G cg21782813 chr7:2030301 MAD1L1 0.43 7.49 0.38 5.97e-13 Schizophrenia; LIHC cis rs7552404 0.807 rs2066183 chr1:76153745 A/G cg03433033 chr1:76189801 ACADM 0.69 10.59 0.5 7.39e-23 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg06634786 chr22:41940651 POLR3H -0.77 -7.75 -0.39 1.09e-13 Vitiligo; LIHC cis rs12701220 0.655 rs10215292 chr7:1135263 A/G cg09177884 chr7:1199841 ZFAND2A -0.51 -6.02 -0.31 4.48e-9 Bronchopulmonary dysplasia; LIHC trans rs61931739 0.534 rs4539411 chr12:34014807 T/C cg26384229 chr12:38710491 ALG10B 0.48 6.79 0.34 5.09e-11 Morning vs. evening chronotype; LIHC cis rs10088262 0.629 rs7833650 chr8:124822969 C/T cg20713898 chr8:124780851 FAM91A1 -0.52 -7.06 -0.36 9.42e-12 Pancreatic cancer; LIHC cis rs2288073 0.965 rs10199334 chr2:24392618 T/C cg06627628 chr2:24431161 ITSN2 -0.56 -7.21 -0.36 3.61e-12 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs10504073 0.647 rs10957357 chr8:49988587 C/A cg00325661 chr8:49890786 NA 0.32 7.55 0.38 3.88e-13 Blood metabolite ratios; LIHC cis rs7119038 0.774 rs7945144 chr11:118608716 A/G cg19308663 chr11:118741387 NA 0.42 6.47 0.33 3.3e-10 Sjögren's syndrome; LIHC cis rs1443512 0.773 rs2366146 chr12:54331002 G/A cg25024717 chr12:54324583 NA -0.32 -6.3 -0.32 8.9e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs3780378 0.935 rs2230724 chr9:5081780 G/A cg02405213 chr9:5042618 JAK2 -0.51 -8.69 -0.43 1.49e-16 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs4409675 0.576 rs2295367 chr1:28224312 C/T cg23691781 chr1:28212827 C1orf38 0.32 7.89 0.39 4.23e-14 Corneal astigmatism; LIHC cis rs1371867 0.846 rs1788189 chr8:101249762 G/T cg06636551 chr8:101224915 SPAG1 0.49 9.35 0.45 1.14e-18 Atrioventricular conduction; LIHC cis rs10791097 0.694 rs2236717 chr11:130739887 G/T cg22079354 chr11:130786696 SNX19 0.42 6.02 0.31 4.43e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs28374715 0.532 rs1899 chr15:41689232 C/T cg18705301 chr15:41695430 NDUFAF1 -1.16 -14.99 -0.63 2.16e-39 Ulcerative colitis; LIHC cis rs4853525 0.522 rs62179715 chr2:191570072 C/T cg10560079 chr2:191398806 TMEM194B -0.42 -5.96 -0.31 6.45e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs12594515 0.967 rs67854274 chr15:45990518 A/G cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs7633770 0.841 rs11130100 chr3:46679198 A/T cg11219411 chr3:46661640 NA -0.54 -9.53 -0.46 3.02e-19 Coronary artery disease; LIHC cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.42 0.45 7.02e-19 Bipolar disorder; LIHC cis rs9457247 1.000 rs408080 chr6:167392522 T/C cg12798992 chr6:167411361 FGFR1OP 0.52 8.05 0.4 1.37e-14 Crohn's disease; LIHC cis rs7552404 0.765 rs211717 chr1:76106969 G/A cg03433033 chr1:76189801 ACADM -0.69 -9.95 -0.47 1.23e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs425277 0.606 rs2257684 chr1:2077872 A/G cg24578937 chr1:2090814 PRKCZ 0.33 6.06 0.31 3.52e-9 Height; LIHC cis rs17021463 0.673 rs4699459 chr4:95292702 G/A cg11021082 chr4:95130006 SMARCAD1 0.44 7.59 0.38 3e-13 Testicular germ cell tumor; LIHC cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg16926213 chr1:1841314 NA 0.32 5.9 0.3 8.86e-9 Body mass index; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg10687131 chr2:20871002 GDF7 0.33 6.71 0.34 8.07e-11 Abdominal aortic aneurysm; LIHC cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg07414643 chr4:187882934 NA 0.24 6.09 0.31 3.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7914558 1.000 rs11191542 chr10:104824324 T/A cg15744005 chr10:104629667 AS3MT -0.37 -8.16 -0.4 6.35e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10791323 0.604 rs2723605 chr11:133711241 C/G cg06766960 chr11:133703094 NA -0.67 -11.24 -0.52 3.68e-25 Childhood ear infection; LIHC cis rs7914558 0.966 rs10786725 chr10:104682357 T/C cg15744005 chr10:104629667 AS3MT -0.4 -9.05 -0.44 1.1e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7909074 0.831 rs11239271 chr10:45376294 A/G cg05187965 chr10:45406764 TMEM72 -0.26 -6.29 -0.32 9.9e-10 Mean corpuscular volume; LIHC cis rs240764 0.853 rs1875401 chr6:101023588 G/A cg09795085 chr6:101329169 ASCC3 -0.49 -6.67 -0.34 1.04e-10 Neuroticism; LIHC cis rs2075371 0.673 rs35290398 chr7:134011773 C/T cg20476274 chr7:133979776 SLC35B4 0.59 7.93 0.39 3.08e-14 Mean platelet volume; LIHC cis rs798554 0.610 rs2644304 chr7:2878779 T/C cg19717773 chr7:2847554 GNA12 -0.41 -7.24 -0.36 2.9e-12 Height; LIHC cis rs765787 0.530 rs1648289 chr15:45516494 A/G cg24006582 chr15:45444508 DUOX1 -0.55 -7.91 -0.39 3.5e-14 Uric acid levels; LIHC cis rs11122272 0.701 rs11122273 chr1:231476789 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -10.39 -0.49 3.69e-22 Hemoglobin concentration; LIHC cis rs796364 0.806 rs74266490 chr2:201005995 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs796364 0.806 rs35200468 chr2:201110368 G/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.81 -8.92 -0.43 2.78e-17 Schizophrenia; LIHC cis rs6912958 0.702 rs2300909 chr6:88212100 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.05 -0.4 1.37e-14 Monocyte percentage of white cells; LIHC cis rs875971 0.862 rs6978028 chr7:65886300 G/C cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs2760061 0.626 rs2527615 chr1:228119283 A/G cg02753203 chr1:228287806 NA -0.48 -7.67 -0.38 1.76e-13 Diastolic blood pressure; LIHC cis rs736408 0.677 rs1042779 chr3:52821011 A/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.21 -0.45 3.27e-18 Bipolar disorder; LIHC trans rs61931739 0.500 rs11052990 chr12:34058647 T/A cg26384229 chr12:38710491 ALG10B 0.51 7.07 0.36 8.59e-12 Morning vs. evening chronotype; LIHC cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg26944245 chr16:421049 TMEM8A;MRPL28 0.41 7.06 0.36 9.54e-12 Bone mineral density (spine);Bone mineral density; LIHC cis rs4819052 0.851 rs28616694 chr21:46674786 G/C cg11663144 chr21:46675770 NA -0.32 -5.96 -0.31 6.38e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs703410 0.545 rs242962 chr10:119313030 G/T cg10846980 chr10:119306025 EMX2;EMX2OS -0.56 -8.52 -0.42 5.19e-16 Subjective well-being (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7953249 0.656 rs6489786 chr12:121397875 A/G cg02403541 chr12:121454288 C12orf43 -0.42 -7.37 -0.37 1.29e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs2549003 1.000 rs2549004 chr5:131827825 C/G cg02551604 chr5:131831745 NA 0.46 6.88 0.35 2.92e-11 Asthma (sex interaction); LIHC cis rs8072100 1.000 rs8065437 chr17:45721653 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.4 -6.35 -0.32 7e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg03351412 chr1:154909251 PMVK 0.7 10.34 0.49 5.29e-22 Prostate cancer; LIHC cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -9.75 -0.47 5.44e-20 Platelet count; LIHC cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 11.25 0.52 3.43e-25 Platelet count; LIHC cis rs9486719 0.947 rs12210834 chr6:96890407 A/T cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs4319547 0.695 rs6489002 chr12:122929822 T/C cg23029597 chr12:123009494 RSRC2 -0.53 -7.42 -0.37 9.25e-13 Body mass index; LIHC cis rs918629 0.798 rs2548595 chr5:95284341 C/T cg10483112 chr5:95245456 ELL2 -0.36 -6.3 -0.32 9.17e-10 IgG glycosylation; LIHC cis rs7617773 0.817 rs13059037 chr3:48287879 A/G cg11946769 chr3:48343235 NME6 0.89 11.15 0.52 8.01e-25 Coronary artery disease; LIHC trans rs1814175 0.617 rs6486020 chr11:49769149 T/G cg15704280 chr7:45808275 SEPT13 -0.95 -19.82 -0.73 8.91e-59 Height; LIHC cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg00149659 chr3:10157352 C3orf10 0.49 5.82 0.3 1.39e-8 Alzheimer's disease; LIHC cis rs912057 0.797 rs1294430 chr6:6744698 A/G cg06612196 chr6:6737390 NA 0.53 9.98 0.48 9.08e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs10752881 0.967 rs10911186 chr1:182972542 A/G ch.1.3577855R chr1:183094577 LAMC1 0.58 10.04 0.48 5.83e-21 Colorectal cancer; LIHC cis rs72781680 0.898 rs112985192 chr2:24102797 G/A cg08917208 chr2:24149416 ATAD2B 0.86 8.11 0.4 9.37e-15 Lymphocyte counts; LIHC cis rs744487 1.000 rs744487 chr1:234726012 A/C cg09691134 chr1:234734475 NA 0.39 6.59 0.34 1.67e-10 LDL cholesterol; LIHC trans rs61931739 0.500 rs10844848 chr12:34409705 A/C cg26384229 chr12:38710491 ALG10B 0.77 9.55 0.46 2.55e-19 Morning vs. evening chronotype; LIHC cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg03517284 chr6:25882590 NA 0.89 12.6 0.56 3.55e-30 Blood metabolite levels; LIHC trans rs1814175 0.817 rs10769648 chr11:50013992 T/C cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs7843479 0.582 rs7818254 chr8:21798316 C/T cg17168535 chr8:21777572 XPO7 0.57 10.65 0.5 4.52e-23 Mean corpuscular volume; LIHC cis rs7408868 1.000 rs6512018 chr19:15282138 T/C cg14696996 chr19:15285081 NOTCH3 0.54 7.08 0.36 8.09e-12 Pulse pressure; LIHC cis rs6665290 0.935 rs6659424 chr1:227197875 A/G cg10327440 chr1:227177885 CDC42BPA -1.2 -26.0 -0.81 5.29e-83 Myeloid white cell count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02726883 chr17:29421732 NF1 0.48 6.55 0.33 2.09e-10 Lung function (FEV1/FVC); LIHC cis rs6882046 0.513 rs446219 chr5:88005827 T/C cg22951263 chr5:87985283 NA -0.38 -6.62 -0.34 1.42e-10 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs9814567 0.727 rs4437193 chr3:134352344 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.53 -8.58 -0.42 3.41e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1799949 0.965 rs8176310 chr17:41199913 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.08 0.31 3.16e-9 Menopause (age at onset); LIHC cis rs7666738 0.830 rs10001479 chr4:98918764 A/G cg05340658 chr4:99064831 C4orf37 -0.66 -12.0 -0.54 6.23e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs5769707 0.837 rs1573726 chr22:50032872 G/A cg01652190 chr22:50026171 C22orf34 -0.31 -6.87 -0.35 3.1e-11 Monocyte count;Monocyte percentage of white cells; LIHC trans rs875971 0.545 rs6460276 chr7:65647277 G/A cg26939375 chr7:64535504 NA 0.4 6.43 0.33 4.35e-10 Aortic root size; LIHC trans rs3783890 0.887 rs35803481 chr14:93803409 G/A cg02802420 chr16:69363236 PDF;COG8 0.34 6.47 0.33 3.44e-10 Body mass index; LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg15382696 chr6:118971807 C6orf204 0.63 6.37 0.33 6.05e-10 Diastolic blood pressure; LIHC trans rs1941687 0.509 rs2282632 chr18:31320229 A/G cg27147174 chr7:100797783 AP1S1 -0.44 -6.18 -0.32 1.77e-9 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs6952808 0.862 rs4721167 chr7:1933224 C/T cg04267008 chr7:1944627 MAD1L1 -0.67 -10.52 -0.49 1.28e-22 Bipolar disorder and schizophrenia; LIHC cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs6570726 1.000 rs386678 chr6:145869010 A/G cg23711669 chr6:146136114 FBXO30 0.52 9.08 0.44 8.79e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs11676348 0.808 rs12694430 chr2:219015799 T/C cg00012203 chr2:219082015 ARPC2 -0.48 -6.13 -0.31 2.4e-9 Ulcerative colitis; LIHC cis rs8180040 0.966 rs13075233 chr3:47420627 T/C cg16586182 chr3:47516702 SCAP -0.57 -10.91 -0.51 5.7e-24 Colorectal cancer; LIHC cis rs35306767 0.855 rs35825568 chr10:950760 C/T cg26597838 chr10:835615 NA 1.08 12.48 0.56 9.9e-30 Eosinophil percentage of granulocytes; LIHC cis rs1008375 0.797 rs6843530 chr4:17593605 G/T cg02297831 chr4:17616191 MED28 0.46 7.1 0.36 7.4e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs798554 0.797 rs1182174 chr7:2875420 G/A cg13628971 chr7:2884303 GNA12 0.5 6.96 0.35 1.71e-11 Height; LIHC cis rs1577917 0.958 rs7453105 chr6:86500761 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -5.94 -0.31 7.01e-9 Response to antipsychotic treatment; LIHC cis rs2404602 0.647 rs11629727 chr15:77009038 G/C cg23625390 chr15:77176239 SCAPER -0.54 -8.93 -0.43 2.6e-17 Blood metabolite levels; LIHC cis rs11958404 0.932 rs113494689 chr5:157428078 G/T cg05962755 chr5:157440814 NA 0.92 10.57 0.5 8.6e-23 IgG glycosylation; LIHC cis rs1865760 0.602 rs9467662 chr6:26021327 G/A cg18357526 chr6:26021779 HIST1H4A 0.49 7.25 0.37 2.78e-12 Height; LIHC cis rs727505 0.954 rs28728448 chr7:124532938 T/A cg23710748 chr7:124431027 NA -0.33 -5.95 -0.31 6.81e-9 Lewy body disease; LIHC cis rs6088590 0.965 rs6088620 chr20:33412022 A/G cg24642439 chr20:33292090 TP53INP2 0.77 10.41 0.49 3.11e-22 Coronary artery disease; LIHC cis rs4908768 0.501 rs6577492 chr1:8575064 C/A cg20416874 chr1:8611966 RERE -0.66 -13.86 -0.6 5.69e-35 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs798554 0.759 rs2644291 chr7:2890456 T/C cg13628971 chr7:2884303 GNA12 0.6 10.08 0.48 4.41e-21 Height; LIHC cis rs3018712 0.532 rs28551086 chr11:68400739 G/A cg20283391 chr11:68216788 NA -0.52 -6.24 -0.32 1.3e-9 Total body bone mineral density; LIHC trans rs6600671 0.932 rs6600663 chr1:121222437 A/T cg09829573 chr1:144692074 NBPF9 -0.39 -6.94 -0.35 1.92e-11 Hip geometry; LIHC cis rs4889911 1.000 rs4889910 chr17:77839795 C/T cg16296745 chr17:78355552 RNF213;LOC100294362 0.39 5.82 0.3 1.37e-8 Electroencephalogram traits; LIHC trans rs9951602 0.833 rs9953548 chr18:76640601 C/T cg02800362 chr5:177631904 HNRNPAB 0.58 7.9 0.39 3.82e-14 Obesity-related traits; LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.29 0.55 5.29e-29 Prudent dietary pattern; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06083525 chr1:27216957 GPN2 -0.49 -6.23 -0.32 1.33e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs62158211 1.000 rs1807282 chr2:114110036 A/T cg17784749 chr2:114082611 LOC440839 0.59 7.2 0.36 3.75e-12 Sleep duration (oversleepers vs undersleepers);Sleep traits (multi-trait analysis);Sleep duration; LIHC cis rs921968 0.509 rs7571743 chr2:219352572 C/T cg02176678 chr2:219576539 TTLL4 0.52 7.09 0.36 7.61e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC trans rs2270927 0.510 rs2937750 chr5:75571511 C/T cg13563193 chr19:33072644 PDCD5 0.85 8.05 0.4 1.4e-14 Mean corpuscular volume; LIHC cis rs4900538 0.787 rs11704 chr14:102808655 C/G cg18135206 chr14:102964638 TECPR2 0.64 9.77 0.47 4.68e-20 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs12135062 0.851 rs2651926 chr1:3101820 C/T cg25382214 chr1:3105252 PRDM16 -0.26 -5.84 -0.3 1.19e-8 Migraine; LIHC cis rs17106184 0.892 rs72900979 chr1:51190314 T/C cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs12479064 0.724 rs112900993 chr2:99948805 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -7.04 -0.36 1.08e-11 Chronic sinus infection; LIHC cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs1552244 0.572 rs67439440 chr3:10169503 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs9911578 1.000 rs8071280 chr17:57010225 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.83 -0.43 5.68e-17 Intelligence (multi-trait analysis); LIHC cis rs40363 0.523 rs757270 chr16:3534451 C/T cg22508957 chr16:3507546 NAT15 -0.41 -7.21 -0.36 3.59e-12 Tuberculosis; LIHC cis rs600806 0.745 rs12136063 chr1:110014170 A/G cg02415029 chr1:110025642 ATXN7L2 0.46 6.3 0.32 9.27e-10 Intelligence (multi-trait analysis); LIHC cis rs2832191 0.755 rs2832192 chr21:30491173 G/T cg08807101 chr21:30365312 RNF160 -0.47 -7.39 -0.37 1.11e-12 Dental caries; LIHC cis rs6442522 0.799 rs4395387 chr3:15503055 G/A cg16303742 chr3:15540471 COLQ 0.49 8.32 0.41 2.14e-15 Uric acid levels; LIHC cis rs477692 0.905 rs485579 chr10:131425492 T/G cg05714579 chr10:131428358 MGMT 0.51 8.65 0.42 1.98e-16 Response to temozolomide; LIHC cis rs1059312 0.932 rs11059916 chr12:129287609 C/A cg09035930 chr12:129282057 SLC15A4 0.68 12.98 0.57 1.29e-31 Systemic lupus erythematosus; LIHC cis rs12744310 0.887 rs36040148 chr1:41801448 T/C cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg15691649 chr6:25882328 NA -0.53 -7.62 -0.38 2.55e-13 Blood metabolite levels; LIHC cis rs11105298 0.891 rs1054807 chr12:89913419 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.33 -0.37 1.63e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1799949 0.628 rs4474733 chr17:41433660 G/T cg05368731 chr17:41323189 NBR1 0.65 10.24 0.48 1.23e-21 Menopause (age at onset); LIHC cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg21782813 chr7:2030301 MAD1L1 0.48 8.15 0.4 7.18e-15 Bipolar disorder and schizophrenia; LIHC cis rs1555399 0.905 rs12879556 chr14:67980074 G/C cg16224230 chr14:67978224 TMEM229B -0.24 -5.82 -0.3 1.37e-8 Parkinson's disease; LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg16145915 chr7:1198662 ZFAND2A -0.44 -12.29 -0.55 5.18e-29 Longevity;Endometriosis; LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg00106254 chr7:1943704 MAD1L1 -0.48 -7.9 -0.39 3.95e-14 Bipolar disorder and schizophrenia; LIHC cis rs7267979 0.932 rs446649 chr20:25467359 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.68 0.34 9.53e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs57590327 0.503 rs13062741 chr3:81887124 C/T cg07356753 chr3:81810745 GBE1 -0.52 -8.09 -0.4 1.07e-14 Extraversion; LIHC trans rs12478296 0.792 rs3924263 chr2:243005167 A/C cg01596870 chr19:55963115 NA -0.67 -9.61 -0.46 1.58e-19 Obesity-related traits; LIHC cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs250677 0.687 rs250678 chr5:148434830 C/T cg18129178 chr5:148520854 ABLIM3 -0.48 -7.52 -0.38 4.9e-13 Breast cancer; LIHC cis rs6466055 0.645 rs4730073 chr7:104855871 A/C cg04380332 chr7:105027541 SRPK2 -0.31 -6.03 -0.31 4.21e-9 Schizophrenia; LIHC cis rs7208859 0.623 rs11657990 chr17:29124200 C/T cg14067834 chr17:29058358 SUZ12P 0.72 7.17 0.36 4.8e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 0.545 rs10950027 chr7:65634151 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.49 0.38 5.77e-13 Aortic root size; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.81 14.8 0.62 1.22e-38 Prudent dietary pattern; LIHC cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg16405210 chr4:1374714 KIAA1530 -0.45 -6.93 -0.35 2.13e-11 Obesity-related traits; LIHC cis rs11031096 0.711 rs10767882 chr11:4205841 G/A cg18678763 chr11:4115507 RRM1 -0.4 -5.86 -0.3 1.08e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs208520 0.690 rs207091 chr6:66799847 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.13 -0.44 5.97e-18 Exhaled nitric oxide output; LIHC cis rs4718428 0.576 rs12698546 chr7:66266906 G/T cg12165864 chr7:66369176 NA -0.45 -6.42 -0.33 4.63e-10 Corneal structure; LIHC cis rs10193935 0.901 rs12619348 chr2:42625586 C/T cg27598129 chr2:42591480 NA -0.69 -10.46 -0.49 2.11e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs4906332 1.000 rs2065015 chr14:103904061 G/T cg04998671 chr14:104000505 TRMT61A 0.42 5.76 0.3 1.86e-8 Coronary artery disease; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg12379764 chr21:47803548 PCNT 0.57 8.57 0.42 3.65e-16 Testicular germ cell tumor; LIHC cis rs11577318 0.579 rs11548246 chr1:26697166 G/A cg18121669 chr1:26560928 CCDC21 -0.49 -7.24 -0.36 3.02e-12 Granulocyte percentage of myeloid white cells; LIHC trans rs1552244 0.572 rs66514627 chr3:10166632 A/C cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs4466137 0.951 rs336958 chr5:82973396 A/G cg16102102 chr5:83017553 HAPLN1 -0.57 -8.39 -0.41 1.34e-15 Prostate cancer; LIHC cis rs9916302 0.904 rs8076546 chr17:37555403 G/A cg03013999 chr17:37608204 MED1 -0.35 -5.78 -0.3 1.71e-8 Glomerular filtration rate (creatinine); LIHC cis rs10751667 0.961 rs7480178 chr11:927108 T/C cg06064525 chr11:970664 AP2A2 -0.49 -12.06 -0.55 3.7e-28 Alzheimer's disease (late onset); LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.75 0.39 1.07e-13 Prudent dietary pattern; LIHC cis rs700651 0.789 rs1976772 chr2:198868201 G/T cg03934865 chr2:198174659 NA 0.46 6.54 0.33 2.25e-10 Intracranial aneurysm; LIHC cis rs614226 0.872 rs787827 chr12:120937794 A/G cg01236616 chr12:121019343 POP5 1.24 19.18 0.72 3.64e-56 Type 1 diabetes nephropathy; LIHC cis rs2839186 0.721 rs13051200 chr21:47701693 A/T cg00612595 chr21:47717864 NA -0.36 -5.86 -0.3 1.1e-8 Testicular germ cell tumor; LIHC cis rs12479064 0.703 rs28382977 chr2:100018304 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -8.89 -0.43 3.62e-17 Chronic sinus infection; LIHC cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.61 -0.46 1.65e-19 Bipolar disorder; LIHC cis rs801193 1.000 rs2707836 chr7:66160435 A/C cg18876405 chr7:65276391 NA 0.43 7.38 0.37 1.24e-12 Aortic root size; LIHC cis rs801193 0.935 rs2286683 chr7:66129843 G/A cg00343986 chr7:65444356 GUSB -0.39 -5.84 -0.3 1.2e-8 Aortic root size; LIHC cis rs6546550 0.901 rs12613947 chr2:70161342 A/G cg02498382 chr2:70120550 SNRNP27 -0.43 -7.46 -0.37 6.98e-13 Prevalent atrial fibrillation; LIHC cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.754 rs17595608 chr4:120250506 C/T cg25214090 chr10:38739885 LOC399744 0.5 8.18 0.4 5.7e-15 Corneal astigmatism; LIHC cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg18357526 chr6:26021779 HIST1H4A 0.9 11.17 0.52 6.86e-25 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg11890956 chr21:40555474 PSMG1 -0.57 -9.55 -0.46 2.63e-19 Cognitive function; LIHC cis rs12493885 0.818 rs11928425 chr3:153773565 G/T cg10247383 chr3:153839028 SGEF 0.65 6.13 0.31 2.41e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.56 7.81 0.39 7.04e-14 Intelligence (multi-trait analysis); LIHC cis rs4979906 1.000 rs2395494 chr10:79458340 C/T cg07817648 chr10:79422355 NA -0.34 -7.4 -0.37 1.1e-12 Mortality in heart failure; LIHC cis rs1823913 0.892 rs35596292 chr2:192111616 C/T cg12404831 chr2:192114017 MYO1B 0.33 6.51 0.33 2.67e-10 Obesity-related traits; LIHC cis rs9640161 0.702 rs3735175 chr7:150020457 C/T cg17279839 chr7:150038598 RARRES2 0.51 10.68 0.5 3.68e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs17401966 0.838 rs12738317 chr1:10419663 C/T cg19773385 chr1:10388646 KIF1B -0.39 -6.97 -0.35 1.67e-11 Hepatocellular carcinoma; LIHC cis rs4808199 0.895 rs8105984 chr19:19374068 T/C cg03709012 chr19:19516395 GATAD2A 0.97 14.67 0.62 4.02e-38 Nonalcoholic fatty liver disease; LIHC cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg16680214 chr1:154839983 KCNN3 -0.34 -5.84 -0.3 1.25e-8 Prostate cancer; LIHC cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 10.0 0.48 8.11e-21 Platelet count; LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg08219700 chr8:58056026 NA 0.52 7.15 0.36 5.24e-12 Developmental language disorder (linguistic errors); LIHC cis rs4788570 0.615 rs4788550 chr16:71720523 C/T cg06353428 chr16:71660113 MARVELD3 1.41 14.74 0.62 2.12e-38 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.512 rs715498 chr22:42148467 G/A cg06634786 chr22:41940651 POLR3H 0.73 7.39 0.37 1.16e-12 Vitiligo; LIHC cis rs7192750 0.586 rs11648353 chr16:71986764 G/A cg06353428 chr16:71660113 MARVELD3 0.77 8.89 0.43 3.46e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs1018836 0.886 rs10112242 chr8:91642631 G/C cg16814680 chr8:91681699 NA -0.62 -9.9 -0.47 1.77e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs3796352 1.000 rs60942590 chr3:53016421 G/A cg07884673 chr3:53033167 SFMBT1 0.91 6.6 0.34 1.58e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs8180040 0.545 rs9311403 chr3:47138878 T/C cg16586182 chr3:47516702 SCAP -0.48 -8.69 -0.43 1.55e-16 Colorectal cancer; LIHC cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg03806693 chr22:41940476 POLR3H -1.14 -13.48 -0.59 1.66e-33 Vitiligo; LIHC cis rs10484885 0.878 rs17763820 chr6:90569634 A/G cg13799429 chr6:90582589 CASP8AP2 -0.67 -6.36 -0.33 6.56e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7107174 0.892 rs2510033 chr11:77941771 T/G cg02023728 chr11:77925099 USP35 0.46 8.54 0.42 4.63e-16 Testicular germ cell tumor; LIHC cis rs35110281 0.837 rs7279968 chr21:45077398 C/G cg21573476 chr21:45109991 RRP1B -0.49 -9.48 -0.46 4.54e-19 Mean corpuscular volume; LIHC cis rs10504229 1.000 rs72652905 chr8:58188355 A/G cg21724239 chr8:58056113 NA 0.46 6.2 0.32 1.64e-9 Developmental language disorder (linguistic errors); LIHC cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -8.02 -0.4 1.7e-14 Type 2 diabetes; LIHC cis rs2243480 1.000 rs58669269 chr7:65951953 T/C cg18252515 chr7:66147081 NA -1.3 -16.7 -0.67 3.38e-46 Diabetic kidney disease; LIHC cis rs2404602 0.647 rs12898416 chr15:77042292 C/G cg03037974 chr15:76606532 NA -0.6 -9.99 -0.48 8.46e-21 Blood metabolite levels; LIHC cis rs337161 0.604 rs11118593 chr1:220878164 C/T cg06786860 chr1:220876396 NA -0.46 -7.45 -0.37 7.75e-13 Response to antipsychotic therapy (extrapyramidal side effects); LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg13922166 chr19:54693569 MBOAT7;TSEN34 0.4 6.24 0.32 1.32e-9 Brain volume in infants (cerebrospinal fluid); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08667777 chr3:51422532 MANF 0.49 7.22 0.36 3.32e-12 Pancreatic cancer; LIHC cis rs644799 0.622 rs1255167 chr11:95500213 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.66 9.67 0.46 9.99e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7945705 0.837 rs10769981 chr11:9024460 T/C cg12365402 chr11:9010492 NRIP3 0.32 7.86 0.39 5.04e-14 Hemoglobin concentration; LIHC cis rs6456156 0.586 rs13208636 chr6:167461965 T/G cg07741184 chr6:167504864 NA 0.29 6.93 0.35 2.04e-11 Primary biliary cholangitis; LIHC trans rs12752401 1.000 rs35190459 chr1:103089554 T/A cg03332897 chr19:740442 PALM 0.5 6.15 0.32 2.2e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs4716602 0.596 rs28451598 chr7:156158974 G/A cg16983916 chr7:156159713 NA -0.32 -5.87 -0.3 1.02e-8 Anti-saccade response; LIHC cis rs9326248 0.798 rs10892079 chr11:117016824 T/G cg26566898 chr11:117069891 TAGLN 0.45 7.12 0.36 6.47e-12 Blood protein levels; LIHC cis rs2412459 1.000 rs8023482 chr15:40307095 A/C cg20255370 chr15:40268687 EIF2AK4 -0.62 -8.1 -0.4 9.64e-15 Response to haloperidol in psychosis; LIHC cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.32 0.41 2.15e-15 Platelet count; LIHC cis rs67311347 0.955 rs1129200 chr3:40532257 T/C cg00656387 chr3:40428638 ENTPD3 0.4 6.35 0.32 6.8e-10 Renal cell carcinoma; LIHC cis rs7131987 0.650 rs7973786 chr12:29462744 C/T cg00204748 chr12:29376779 FAR2 0.38 7.0 0.35 1.4e-11 QT interval; LIHC cis rs6893300 0.542 rs7736300 chr5:179196898 G/A cg14593053 chr5:179126677 CANX 0.45 8.14 0.4 7.48e-15 Resting heart rate; LIHC cis rs240764 0.746 rs240141 chr6:101084946 G/A cg09795085 chr6:101329169 ASCC3 0.51 7.22 0.36 3.3e-12 Neuroticism; LIHC trans rs7613875 0.663 rs6762477 chr3:50093209 G/A cg21659725 chr3:3221576 CRBN -0.54 -8.06 -0.4 1.25e-14 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00777555 chr3:57583074 ARF4 0.42 7.03 0.36 1.13e-11 Cognitive function; LIHC cis rs8062405 0.755 rs55792032 chr16:28599411 A/G cg07382826 chr16:28625726 SULT1A1 0.49 7.72 0.39 1.3e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2108225 0.934 rs2301988 chr7:107443833 A/G cg18560240 chr7:107437656 SLC26A3 0.48 7.41 0.37 1.03e-12 Ulcerative colitis; LIHC cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs10489202 1.000 rs34774552 chr1:168032245 G/A cg24449463 chr1:168025552 DCAF6 -0.51 -6.52 -0.33 2.54e-10 Schizophrenia; LIHC cis rs9611565 0.568 rs2413656 chr22:42129357 G/T cg06634786 chr22:41940651 POLR3H 0.57 6.36 0.33 6.55e-10 Vitiligo; LIHC cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg07414643 chr4:187882934 NA 0.23 5.97 0.31 6.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs858239 0.600 rs7776644 chr7:23119307 C/T cg23682824 chr7:23144976 KLHL7 0.4 5.9 0.3 8.57e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7937890 0.532 rs2575832 chr11:14488810 A/G cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.3 0.61 1.06e-36 Prudent dietary pattern; LIHC cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg17554472 chr22:41940697 POLR3H 0.55 5.89 0.3 9.21e-9 Vitiligo; LIHC trans rs4718428 0.672 rs12530806 chr7:66390724 A/G cg10756647 chr7:56101905 PSPH 0.63 8.75 0.43 9.95e-17 Corneal structure; LIHC cis rs9457247 0.740 rs10946204 chr6:167451129 T/C cg07741184 chr6:167504864 NA 0.32 7.19 0.36 4.24e-12 Crohn's disease; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs5758511 0.633 rs5758690 chr22:42668295 C/G cg20195005 chr22:42527684 CYP2D6 0.31 5.83 0.3 1.29e-8 Birth weight; LIHC trans rs4714291 0.698 rs9296321 chr6:40118352 C/T cg02267698 chr19:7991119 CTXN1 -0.37 -6.2 -0.32 1.59e-9 Strep throat; LIHC cis rs2439831 0.850 rs694985 chr15:43813387 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.53 7.2 0.36 3.93e-12 Lung cancer in ever smokers; LIHC cis rs7584330 0.554 rs74449293 chr2:238426458 G/A cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs2408955 0.521 rs10875753 chr12:48557141 C/T cg21466736 chr12:48725269 NA -0.63 -9.28 -0.45 2e-18 Glycated hemoglobin levels; LIHC cis rs11190604 0.945 rs7091356 chr10:102292268 G/C cg07080220 chr10:102295463 HIF1AN 0.57 8.11 0.4 9.3e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1873147 0.569 rs12593573 chr15:63309919 G/A cg12160578 chr15:63334699 TPM1 0.67 8.87 0.43 4.13e-17 Orofacial clefts; LIHC cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs72781680 0.898 rs56216411 chr2:23934533 G/A cg08917208 chr2:24149416 ATAD2B 0.97 8.25 0.41 3.56e-15 Lymphocyte counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21819024 chr1:52344978 NRD1 0.53 7.57 0.38 3.56e-13 Pancreatic cancer; LIHC cis rs2288073 0.896 rs13404513 chr2:24410780 G/A cg06627628 chr2:24431161 ITSN2 -0.58 -7.63 -0.38 2.32e-13 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs67311347 1.000 rs12638199 chr3:40475285 A/G cg24209194 chr3:40518798 ZNF619 0.49 7.26 0.37 2.71e-12 Renal cell carcinoma; LIHC cis rs11792861 0.926 rs12686736 chr9:111888739 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.55 0.42 4.08e-16 Menarche (age at onset); LIHC cis rs12602486 0.744 rs12603404 chr17:42223914 G/A cg08193365 chr17:42277699 NA 1.08 7.74 0.39 1.12e-13 Glycated hemoglobin levels; LIHC cis rs965469 0.843 rs6051842 chr20:3397434 T/C cg25506879 chr20:3388711 C20orf194 -0.53 -6.21 -0.32 1.51e-9 IFN-related cytopenia; LIHC cis rs13088318 0.504 rs55759062 chr3:101202152 C/T cg19452782 chr3:101232218 SENP7 0.41 6.12 0.31 2.5e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9517302 0.615 rs3752974 chr13:99097827 T/C cg24044564 chr13:99115944 STK24 0.49 6.93 0.35 2.07e-11 Obesity-related traits; LIHC cis rs548181 0.736 rs540436 chr11:125512619 A/G cg03464685 chr11:125439445 EI24 0.78 8.77 0.43 8.75e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4969178 0.896 rs11077361 chr17:76397128 A/G cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC trans rs1005277 0.522 rs11011343 chr10:38002698 A/G cg27523141 chr10:43048294 ZNF37B 0.39 6.91 0.35 2.32e-11 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.13 0.55 2e-28 Prudent dietary pattern; LIHC cis rs12586317 0.511 rs11540758 chr14:35498485 C/T cg16230307 chr14:35515116 FAM177A1 0.78 13.24 0.58 1.39e-32 Psoriasis; LIHC cis rs9534288 0.731 rs2404730 chr13:46617381 G/A cg15192986 chr13:46630673 CPB2 -0.55 -8.24 -0.41 3.66e-15 Blood protein levels; LIHC cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg23758822 chr17:41437982 NA 0.94 17.82 0.69 1.05e-50 Menopause (age at onset); LIHC cis rs7772486 0.875 rs1331644 chr6:146398660 T/C cg23711669 chr6:146136114 FBXO30 0.57 9.82 0.47 3.34e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs10792665 0.575 rs10736756 chr11:82560810 A/G cg24227371 chr11:82718527 RAB30 0.26 6.18 0.32 1.81e-9 Obesity-related traits; LIHC cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg18404041 chr3:52824283 ITIH1 -0.47 -7.79 -0.39 8.26e-14 Electroencephalogram traits; LIHC cis rs4423214 1.000 rs2276360 chr11:71169547 C/G cg24826892 chr11:71159390 DHCR7 0.49 6.23 0.32 1.39e-9 Vitamin D levels; LIHC cis rs921968 0.643 rs535830 chr2:219372233 C/G cg17980119 chr2:219472607 PLCD4 0.36 6.14 0.31 2.34e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7937682 0.632 rs10891294 chr11:111699224 C/T cg09085632 chr11:111637200 PPP2R1B 0.94 13.88 0.6 4.66e-35 Primary sclerosing cholangitis; LIHC cis rs875971 1.000 rs7801282 chr7:65613687 C/T cg18876405 chr7:65276391 NA -0.39 -6.89 -0.35 2.67e-11 Aortic root size; LIHC cis rs2153535 0.504 rs5001323 chr6:8451605 C/T cg07606381 chr6:8435919 SLC35B3 0.8 11.89 0.54 1.65e-27 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02996269 chr4:106394692 PPA2 0.43 6.56 0.33 2.01e-10 Lung function (FEV1/FVC); LIHC cis rs60515486 0.702 rs11039197 chr11:47378399 A/G cg20307385 chr11:47447363 PSMC3 -0.5 -5.74 -0.3 2.03e-8 Lymphocyte counts; LIHC cis rs10499694 0.697 rs3779074 chr7:50612202 A/G cg14593290 chr7:50529359 DDC -0.41 -6.83 -0.35 3.81e-11 Body mass index; LIHC cis rs2075165 0.935 rs933489 chr1:156235120 T/C cg08469215 chr1:156261351 TMEM79 0.39 6.25 0.32 1.21e-9 Tonsillectomy; LIHC cis rs15676 0.561 rs10739736 chr9:131577981 A/T cg00228799 chr9:131580591 ENDOG 0.47 7.14 0.36 5.51e-12 Blood metabolite levels; LIHC cis rs782590 0.967 rs62165173 chr2:55741666 T/C cg03859395 chr2:55845619 SMEK2 0.92 15.84 0.65 9.33e-43 Metabolic syndrome; LIHC cis rs11112613 0.775 rs12371537 chr12:105971425 T/C cg03607813 chr12:105948248 NA 0.62 11.86 0.54 2.07e-27 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs875971 0.862 rs6960446 chr7:65733259 A/G cg18252515 chr7:66147081 NA 0.47 6.89 0.35 2.67e-11 Aortic root size; LIHC cis rs2280018 0.526 rs2966129 chr16:15152927 A/C cg07549590 chr16:15018862 NA 0.41 7.7 0.38 1.52e-13 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11098499 0.826 rs4472123 chr4:120236630 T/A cg09307838 chr4:120376055 NA 0.69 10.68 0.5 3.71e-23 Corneal astigmatism; LIHC cis rs722599 0.562 rs2287400 chr14:75182937 G/A cg11812906 chr14:75593930 NEK9 0.38 5.94 0.31 7.21e-9 IgG glycosylation; LIHC trans rs12478296 0.681 rs6598999 chr2:242994405 C/A cg01596870 chr19:55963115 NA -0.65 -9.5 -0.46 3.68e-19 Obesity-related traits; LIHC trans rs1814175 0.511 rs61905634 chr11:49819736 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.22e-11 Height; LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs2251381 0.750 rs2251087 chr21:30527999 C/T cg08807101 chr21:30365312 RNF160 0.76 10.14 0.48 2.64e-21 Selective IgA deficiency; LIHC cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg02891314 chr5:179741120 GFPT2 -0.43 -6.01 -0.31 4.71e-9 Height; LIHC cis rs9303401 0.527 rs12946522 chr17:56768103 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.9 11.64 0.53 1.32e-26 Cognitive test performance; LIHC cis rs4423214 0.802 rs4616066 chr11:71183846 G/A cg05163923 chr11:71159392 DHCR7 -0.6 -7.9 -0.39 3.79e-14 Vitamin D levels; LIHC cis rs2303759 0.709 rs8102658 chr19:49828855 C/T cg22307029 chr19:49891270 CCDC155 0.57 8.81 0.43 6.63e-17 Multiple sclerosis; LIHC cis rs2637030 0.559 rs370594 chr5:52955554 C/T cg06476337 chr5:52856530 NDUFS4 0.43 6.76 0.34 5.88e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs4689592 0.622 rs2276968 chr4:7070118 T/G cg02503808 chr4:7069936 GRPEL1 0.79 11.4 0.52 9.42e-26 Monocyte percentage of white cells; LIHC cis rs8062405 0.895 rs62036658 chr16:28850371 T/G cg00204512 chr16:28754710 NA 0.36 6.49 0.33 2.98e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7520050 0.807 rs6671802 chr1:46124663 A/G cg03146154 chr1:46216737 IPP 0.5 8.54 0.42 4.4e-16 Red blood cell count;Reticulocyte count; LIHC cis rs6952808 0.929 rs11761270 chr7:1923695 C/T cg04267008 chr7:1944627 MAD1L1 -0.69 -11.0 -0.51 2.78e-24 Bipolar disorder and schizophrenia; LIHC cis rs4076764 0.914 rs4638099 chr1:163365521 A/G cg24596788 chr1:163392923 NA 0.21 6.49 0.33 3.1e-10 Motion sickness; LIHC cis rs9303401 0.704 rs740605 chr17:56604811 C/T cg05425664 chr17:57184151 TRIM37 -0.5 -7.25 -0.37 2.77e-12 Cognitive test performance; LIHC trans rs875971 0.502 rs11769702 chr7:65720516 A/C cg26939375 chr7:64535504 NA 0.4 6.39 0.33 5.4e-10 Aortic root size; LIHC cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg03264133 chr6:25882463 NA 0.59 7.87 0.39 4.73e-14 Blood metabolite levels; LIHC cis rs25645 0.830 rs4072639 chr17:38189049 G/A cg17467752 chr17:38218738 THRA -0.53 -9.29 -0.45 1.84e-18 Myeloid white cell count; LIHC cis rs11627756 0.957 rs6575929 chr14:103149447 T/G cg12046867 chr14:103022105 NA 0.39 5.95 0.31 6.78e-9 Mean platelet volume; LIHC cis rs651907 0.535 rs35810977 chr3:101531380 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.63 9.93 0.47 1.39e-20 Colorectal cancer; LIHC cis rs116095464 0.558 rs10043002 chr5:226753 G/A cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs7618501 0.521 rs11130222 chr3:49901060 A/T cg05623727 chr3:50126028 RBM5 0.36 5.99 0.31 5.43e-9 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.855 rs12761180 chr10:872086 C/T cg20503657 chr10:835505 NA 1.34 13.9 0.6 3.84e-35 Eosinophil percentage of granulocytes; LIHC cis rs4450131 0.522 rs4962680 chr10:126358833 C/T cg20435097 chr10:126320824 FAM53B 0.67 12.33 0.55 3.71e-29 White blood cell count (basophil); LIHC cis rs7572733 0.534 rs1983359 chr2:198805098 C/T cg10820045 chr2:198174542 NA 0.48 7.47 0.37 6.93e-13 Dermatomyositis; LIHC cis rs7223966 1.000 rs7223966 chr17:61893398 G/A cg05941027 chr17:61774174 LIMD2 0.35 7.47 0.37 6.95e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9911578 1.000 rs9892795 chr17:57023054 G/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.89e-17 Intelligence (multi-trait analysis); LIHC trans rs4927850 0.723 rs7630825 chr3:195753740 T/C cg16724585 chr3:197361211 NA -0.44 -6.37 -0.33 5.95e-10 Pancreatic cancer; LIHC cis rs593982 0.858 rs537385 chr11:65504900 G/A cg08755490 chr11:65554678 OVOL1 0.55 8.56 0.42 3.82e-16 Atopic dermatitis; LIHC cis rs4006360 0.646 rs8080447 chr17:39301276 T/A cg20663846 chr17:39254439 KRTAP4-8 0.2 5.8 0.3 1.48e-8 Bipolar disorder and schizophrenia; LIHC cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg04267008 chr7:1944627 MAD1L1 -0.62 -9.93 -0.47 1.36e-20 Bipolar disorder and schizophrenia; LIHC cis rs7408868 1.000 rs10407320 chr19:15275716 G/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.79 -0.3 1.61e-8 Pulse pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25936770 chr7:122321411 CADPS2 0.42 6.41 0.33 4.95e-10 Pancreatic cancer; LIHC trans rs7668874 0.779 rs1992270 chr4:116806638 C/T cg08917878 chr5:172668965 NA -0.31 -6.03 -0.31 4.17e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs12142240 0.698 rs932816 chr1:46859749 G/A cg00530320 chr1:46809349 NSUN4 0.53 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg14004847 chr7:1930337 MAD1L1 -0.48 -6.98 -0.35 1.5e-11 Bipolar disorder and schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21583412 chr17:27621436 NUFIP2 0.38 6.07 0.31 3.35e-9 Lung function (FEV1/FVC); LIHC cis rs360798 0.532 rs13013218 chr2:63011671 C/T cg17519650 chr2:63277830 OTX1 -0.53 -8.17 -0.4 6.25e-15 Coronary artery disease; LIHC cis rs62458065 0.640 rs10271491 chr7:32530665 C/A cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -7.27 -0.37 2.39e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs2404602 0.532 rs206205 chr15:76736091 T/G cg03037974 chr15:76606532 NA 0.66 12.17 0.55 1.53e-28 Blood metabolite levels; LIHC cis rs2204008 0.744 rs11182316 chr12:38499552 G/A cg13010199 chr12:38710504 ALG10B 0.57 6.65 0.34 1.19e-10 Bladder cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13671128 chr19:1612344 TCF3 0.5 6.26 0.32 1.16e-9 Systolic blood pressure; LIHC trans rs7980799 0.682 rs10161491 chr12:33623806 T/C cg26384229 chr12:38710491 ALG10B -0.45 -6.1 -0.31 2.86e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs5758511 0.514 rs5751221 chr22:42516366 C/T cg20195005 chr22:42527684 CYP2D6 0.32 6.23 0.32 1.39e-9 Birth weight; LIHC cis rs6952808 0.595 rs2398705 chr7:2164995 G/A cg21782813 chr7:2030301 MAD1L1 0.39 6.63 0.34 1.33e-10 Bipolar disorder and schizophrenia; LIHC cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg13047869 chr3:10149882 C3orf24 0.55 6.5 0.33 2.83e-10 Alzheimer's disease; LIHC cis rs651907 0.557 rs7612283 chr3:101434919 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.61 0.5 6.33e-23 Colorectal cancer; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07697189 chr5:171766855 SH3PXD2B 0.38 6.15 0.32 2.21e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2033711 0.870 rs7408188 chr19:58939389 T/G cg03735888 chr19:58951602 ZNF132 0.36 5.95 0.31 6.5e-9 Uric acid clearance; LIHC cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg13397359 chr6:42928475 GNMT 0.83 12.2 0.55 1.1e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6463523 0.864 rs73047957 chr7:759373 A/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.97 16.89 0.67 5.92e-47 Subjective well-being; LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg19635926 chr16:89946313 TCF25 0.55 7.39 0.37 1.11e-12 Skin colour saturation; LIHC cis rs6121246 0.909 rs2376992 chr20:30263418 T/C cg13852791 chr20:30311386 BCL2L1 0.97 9.8 0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs55665837 0.559 rs9667144 chr11:14421101 C/T cg19336497 chr11:14380999 RRAS2 0.56 10.28 0.49 9.19e-22 Vitamin D levels; LIHC cis rs3736485 0.966 rs9920124 chr15:51908942 T/A cg08986416 chr15:51914746 DMXL2 -0.47 -6.97 -0.35 1.64e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7208859 0.623 rs8075163 chr17:29106310 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC cis rs10751667 0.643 rs10794352 chr11:946294 T/C cg06064525 chr11:970664 AP2A2 -0.56 -15.07 -0.63 1.01e-39 Alzheimer's disease (late onset); LIHC trans rs1814175 0.645 rs847635 chr11:49923323 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs7129556 0.520 rs4945185 chr11:77318142 G/A cg21573582 chr11:77300763 AQP11 0.38 5.71 0.3 2.45e-8 Weight loss (gastric bypass surgery); LIHC cis rs6964587 0.626 rs10234074 chr7:91520119 C/T cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.22e-24 Breast cancer; LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.19e-10 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.913 rs59056571 chr11:68272973 T/G cg20283391 chr11:68216788 NA -0.52 -7.74 -0.39 1.14e-13 Total body bone mineral density; LIHC cis rs77633900 0.772 rs284903 chr15:76744813 G/A cg21673338 chr15:77095150 SCAPER -0.53 -6.1 -0.31 2.79e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs1059312 1.000 rs2291350 chr12:129283711 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.71 -14.08 -0.61 8.16e-36 Systemic lupus erythematosus; LIHC cis rs1395 0.744 rs11686131 chr2:27508710 C/T cg22903471 chr2:27725779 GCKR -0.43 -6.32 -0.32 7.98e-10 Blood metabolite levels; LIHC cis rs1355223 0.902 rs836462 chr11:34743263 G/A cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7772486 0.817 rs2144477 chr6:146406248 C/T cg05347473 chr6:146136440 FBXO30 0.37 5.95 0.31 6.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12908161 0.959 rs35557864 chr15:85331629 A/G cg12863693 chr15:85201151 NMB 0.45 6.33 0.32 7.53e-10 Schizophrenia; LIHC cis rs10193935 0.901 rs1390609 chr2:42666230 G/T cg27598129 chr2:42591480 NA 0.71 10.51 0.49 1.36e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs9322817 0.691 rs17680345 chr6:105337409 A/T cg02098413 chr6:105308735 HACE1 0.39 7.48 0.38 6.25e-13 Thyroid stimulating hormone; LIHC cis rs7089973 0.584 rs7908665 chr10:116611337 G/A cg03647239 chr10:116582469 FAM160B1 0.46 6.77 0.34 5.47e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs919433 0.679 rs13394214 chr2:198527371 C/T cg03934865 chr2:198174659 NA 0.47 6.99 0.35 1.42e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6570726 0.818 rs398812 chr6:145817271 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.69 0.46 9.2e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6089829 0.962 rs6122344 chr20:61661738 C/T cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs7582720 1.000 rs114393235 chr2:203795987 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02006803 chr2:128990870 NA -0.46 -6.06 -0.31 3.52e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs2559856 1.000 rs2695292 chr12:102087290 G/A cg12924262 chr12:102091054 CHPT1 0.53 8.5 0.42 5.98e-16 Blood protein levels; LIHC cis rs7264396 1.000 rs6088881 chr20:34165609 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.41 6.99 0.35 1.43e-11 Total cholesterol levels; LIHC cis rs4671400 0.571 rs6738482 chr2:61494901 A/G cg14146966 chr2:61757674 XPO1 -0.36 -5.75 -0.3 2.01e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs10751667 0.643 rs10902257 chr11:973577 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.2 0.48 1.73e-21 Alzheimer's disease (late onset); LIHC cis rs13217239 0.646 rs12201393 chr6:26975690 C/A cg18867708 chr6:26865862 GUSBL1 0.52 8.1 0.4 9.8e-15 Schizophrenia; LIHC cis rs477895 0.713 rs12787852 chr11:63954648 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.57 0.46 2.25e-19 Mean platelet volume; LIHC cis rs35110281 0.837 rs7279968 chr21:45077398 C/G cg04455712 chr21:45112962 RRP1B 0.44 7.63 0.38 2.42e-13 Mean corpuscular volume; LIHC cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg15691649 chr6:25882328 NA -0.54 -7.75 -0.39 1.07e-13 Blood metabolite levels; LIHC cis rs1113500 0.897 rs10785832 chr1:108638899 G/A cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.87e-12 Growth-regulated protein alpha levels; LIHC cis rs2933343 0.903 rs2638846 chr3:128587163 A/T cg25356066 chr3:128598488 ACAD9 0.55 7.36 0.37 1.4e-12 IgG glycosylation; LIHC cis rs763121 0.853 rs4820345 chr22:39091151 T/C cg06022373 chr22:39101656 GTPBP1 0.67 11.59 0.53 1.95e-26 Menopause (age at onset); LIHC trans rs7395662 0.500 rs1605360 chr11:48685714 G/A cg03929089 chr4:120376271 NA -0.43 -6.49 -0.33 3.07e-10 HDL cholesterol; LIHC cis rs7826238 0.566 rs2945886 chr8:8148270 C/G cg06636001 chr8:8085503 FLJ10661 0.61 10.55 0.5 1.03e-22 Systolic blood pressure; LIHC cis rs1046896 0.586 rs9897951 chr17:80810662 T/C cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.43 0.37 8.76e-13 Glycated hemoglobin levels; LIHC cis rs1005277 0.579 rs1780136 chr10:38501453 A/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs2242116 0.896 rs724448 chr3:46935734 A/C cg27129171 chr3:47204927 SETD2 0.48 7.67 0.38 1.79e-13 Birth weight; LIHC cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg21951975 chr1:209979733 IRF6 0.44 7.08 0.36 8.02e-12 Cleft lip with or without cleft palate; LIHC cis rs4788570 0.667 rs8052910 chr16:71790221 A/G cg06353428 chr16:71660113 MARVELD3 1.38 14.61 0.62 6.7e-38 Intelligence (multi-trait analysis); LIHC cis rs1538970 0.781 rs713358 chr1:45988267 C/G cg24296786 chr1:45957014 TESK2 -0.47 -6.46 -0.33 3.58e-10 Platelet count; LIHC cis rs2933343 0.700 rs1680779 chr3:128614770 G/A cg24203234 chr3:128598194 ACAD9 0.44 6.02 0.31 4.46e-9 IgG glycosylation; LIHC cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg11062466 chr8:58055876 NA 0.51 6.98 0.35 1.52e-11 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01111842 chr9:140444966 PNPLA7;MRPL41 -0.53 -6.85 -0.35 3.54e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7715806 0.500 rs72633986 chr5:75006449 T/A cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7904368 0.951 rs7905776 chr10:16853609 C/T cg14835575 chr10:16859367 RSU1 0.59 8.28 0.41 2.72e-15 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs9902453 0.845 rs12601963 chr17:28246358 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.07e-27 Coffee consumption (cups per day); LIHC cis rs4665809 1.000 rs4665308 chr2:26330514 C/A cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs10845606 1.000 rs10845606 chr12:12834894 G/T cg04607235 chr12:12878440 APOLD1 -0.71 -9.04 -0.44 1.18e-17 Systemic lupus erythematosus; LIHC cis rs4820294 0.669 rs35662099 chr22:38053909 C/T cg26138144 chr22:38071188 LGALS1 0.42 7.81 0.39 7.3e-14 Fat distribution (HIV); LIHC cis rs1997103 1.000 rs6949244 chr7:55411301 C/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2758596 1.000 rs2758596 chr1:156189286 C/T cg25208724 chr1:156163844 SLC25A44 0.74 7.79 0.39 8.02e-14 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs7208859 0.623 rs55814012 chr17:29077697 T/A cg13385521 chr17:29058706 SUZ12P 0.81 7.96 0.4 2.64e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7826238 0.720 rs12546760 chr8:8374836 A/G cg06636001 chr8:8085503 FLJ10661 -0.49 -7.34 -0.37 1.54e-12 Systolic blood pressure; LIHC cis rs2066819 1.000 rs118130855 chr12:56677979 T/A cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs9399135 0.935 rs987690 chr6:135350379 A/G cg22676075 chr6:135203613 NA 0.4 6.45 0.33 3.83e-10 Red blood cell count; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs3820068 0.705 rs2145397 chr1:15896199 G/A cg17385448 chr1:15911702 AGMAT 0.4 6.74 0.34 6.62e-11 Systolic blood pressure; LIHC cis rs2645694 0.532 rs2645706 chr4:77829606 A/C cg06046430 chr4:77819534 ANKRD56 0.53 6.55 0.33 2.13e-10 Emphysema distribution in smoking; LIHC cis rs796364 1.000 rs281760 chr2:200787804 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.24 0.41 3.73e-15 Schizophrenia; LIHC cis rs17685 0.753 rs4728550 chr7:75670988 C/A cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.29 0.32 9.72e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg23262073 chr20:60523788 NA -0.38 -7.65 -0.38 2e-13 Obesity-related traits; LIHC cis rs9921222 0.521 rs78867928 chr16:368986 C/T cg08923669 chr16:420230 MRPL28 -0.45 -5.88 -0.3 9.97e-9 Bone mineral density (spine);Bone mineral density; LIHC trans rs2243480 1.000 rs451396 chr7:65484074 T/A cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs11098499 0.821 rs10032151 chr4:120391628 C/T cg09307838 chr4:120376055 NA 0.77 12.18 0.55 1.32e-28 Corneal astigmatism; LIHC cis rs9640161 0.659 rs17837498 chr7:150009679 A/G cg17279839 chr7:150038598 RARRES2 0.49 10.02 0.48 6.78e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg12311346 chr5:56204834 C5orf35 -0.58 -7.65 -0.38 2.08e-13 Initial pursuit acceleration; LIHC cis rs10845606 1.000 rs10845609 chr12:12838920 T/A cg04607235 chr12:12878440 APOLD1 -0.71 -8.79 -0.43 7.44e-17 Systemic lupus erythematosus; LIHC cis rs9303401 0.659 rs12952325 chr17:56899371 G/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.82 0.43 5.9e-17 Cognitive test performance; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg23174392 chr13:114009751 GRTP1 -0.39 -6.65 -0.34 1.19e-10 Pain; LIHC cis rs4819052 0.851 rs8130285 chr21:46671701 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.73 0.54 6.22e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs801193 1.000 rs2659912 chr7:66157999 G/C cg26939375 chr7:64535504 NA 0.43 6.84 0.35 3.64e-11 Aortic root size; LIHC cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg13395646 chr4:1353034 KIAA1530 -0.64 -9.13 -0.44 5.98e-18 Obesity-related traits; LIHC cis rs6762477 0.748 rs9831967 chr3:50217234 C/T cg24110177 chr3:50126178 RBM5 0.48 7.9 0.39 3.86e-14 Menarche (age at onset); LIHC cis rs2153535 0.580 rs9406161 chr6:8466144 G/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs6684514 1.000 rs12563631 chr1:156258953 T/C cg16558208 chr1:156270281 VHLL 0.53 10.01 0.48 7.3e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs78062588 0.892 rs6680410 chr1:154550724 C/T cg24304309 chr1:154577895 ADAR -0.56 -6.3 -0.32 9.35e-10 Lung cancer; LIHC cis rs986417 0.818 rs1998189 chr14:60974987 A/T cg27398547 chr14:60952738 C14orf39 0.78 8.57 0.42 3.61e-16 Gut microbiota (bacterial taxa); LIHC cis rs7727544 0.684 rs272889 chr5:131665378 A/G cg07395648 chr5:131743802 NA -0.29 -6.01 -0.31 4.74e-9 Blood metabolite levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27010136 chr7:1131122 GPER;C7orf50 0.42 6.52 0.33 2.59e-10 Longevity; LIHC cis rs9814567 0.929 rs13088413 chr3:134309977 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.15 0.55 1.74e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg20891558 chr2:74357851 NA 0.82 16.82 0.67 1.06e-46 Gestational age at birth (maternal effect); LIHC cis rs2836974 0.644 rs2836982 chr21:40689171 C/A cg11890956 chr21:40555474 PSMG1 -0.48 -7.7 -0.38 1.43e-13 Cognitive function; LIHC cis rs1775715 0.870 rs11008702 chr10:32244818 T/G cg14930904 chr10:32216787 ARHGAP12 0.39 7.01 0.35 1.31e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs400736 0.655 rs11121086 chr1:8151224 C/T cg25007680 chr1:8021821 PARK7 -0.53 -8.05 -0.4 1.39e-14 Response to antidepressants and depression; LIHC trans rs1814175 0.765 rs11493326 chr11:50018063 T/C cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.21e-53 Height; LIHC trans rs7618501 0.601 rs2624825 chr3:50154989 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.57 -9.22 -0.45 3.13e-18 Intelligence (multi-trait analysis); LIHC cis rs7078219 0.505 rs6584281 chr10:101286480 A/G cg06854084 chr10:101292507 NKX2-3 -0.32 -5.89 -0.3 9.12e-9 Dental caries; LIHC cis rs79976124 0.797 rs79522358 chr6:66641140 C/G cg07460842 chr6:66804631 NA 0.65 6.92 0.35 2.19e-11 Type 2 diabetes; LIHC cis rs11628318 0.515 rs8009257 chr14:103155594 A/G cg01864069 chr14:103024347 NA 0.36 5.88 0.3 9.68e-9 Platelet count; LIHC cis rs9303401 0.659 rs72828726 chr17:56951217 C/G cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.23 0.55 8.67e-29 Cognitive test performance; LIHC cis rs2274273 0.870 rs3825616 chr14:55853288 G/C cg04306507 chr14:55594613 LGALS3 0.33 6.05 0.31 3.79e-9 Protein biomarker; LIHC cis rs2108225 0.900 rs2051956 chr7:107441358 G/C cg18560240 chr7:107437656 SLC26A3 -0.49 -7.72 -0.39 1.26e-13 Ulcerative colitis; LIHC cis rs10870270 0.956 rs7904594 chr10:133734671 C/T cg08754478 chr10:133766260 PPP2R2D -0.56 -8.27 -0.41 3.08e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6717918 0.781 rs4640379 chr2:233141377 A/G ch.2.233013039R chr2:233304795 NA -0.49 -5.81 -0.3 1.46e-8 Height; LIHC cis rs4144743 1.000 rs4144743 chr17:45323125 A/G cg18085866 chr17:45331354 ITGB3 -0.57 -8.57 -0.42 3.54e-16 Body mass index; LIHC cis rs11628318 0.713 rs1998419 chr14:103050397 C/G cg12046867 chr14:103022105 NA -0.59 -8.57 -0.42 3.55e-16 Platelet count; LIHC cis rs7684253 0.550 rs4566710 chr4:57745463 G/A cg26694713 chr4:57773883 REST -0.41 -5.84 -0.3 1.19e-8 Migraine; LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.19 -0.32 1.73e-9 Total body bone mineral density; LIHC cis rs7615952 0.558 rs17334039 chr3:125540308 A/G cg05084668 chr3:125655381 ALG1L -0.35 -6.38 -0.33 5.75e-10 Blood pressure (smoking interaction); LIHC cis rs116095464 0.558 rs9312977 chr5:221916 G/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs11190604 1.000 rs11190599 chr10:102295420 C/T cg07080220 chr10:102295463 HIF1AN 0.55 8.07 0.4 1.17e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs11626933 0.885 rs28517514 chr14:90788709 G/A cg14092571 chr14:90743983 NA -0.78 -12.8 -0.57 6.17e-31 Gut microbiota (bacterial taxa); LIHC cis rs2230307 0.536 rs554742 chr1:100512568 G/A cg24955406 chr1:100503596 HIAT1 0.67 6.48 0.33 3.19e-10 Carotid intima media thickness; LIHC cis rs11792861 0.926 rs59904140 chr9:111910051 C/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.71 -0.34 8e-11 Menarche (age at onset); LIHC cis rs875971 0.790 rs10257911 chr7:65743770 A/G cg18252515 chr7:66147081 NA 0.45 6.59 0.34 1.69e-10 Aortic root size; LIHC cis rs9814567 1.000 rs4417907 chr3:134291363 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.94 -0.31 6.88e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs933688 1.000 rs10058025 chr5:90689052 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.44 0.66 3.67e-45 Smoking behavior; LIHC cis rs7772486 0.686 rs857880 chr6:145971115 T/C cg13319975 chr6:146136371 FBXO30 0.37 6.02 0.31 4.42e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6442522 0.673 rs1869855 chr3:15501142 G/T cg16303742 chr3:15540471 COLQ 0.43 7.25 0.36 2.81e-12 Uric acid levels; LIHC cis rs225245 0.791 rs7406966 chr17:34013636 A/C cg05299278 chr17:33885742 SLFN14 0.23 6.38 0.33 5.83e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs11958404 0.789 rs7736318 chr5:157477593 A/G cg05962755 chr5:157440814 NA 1.0 11.73 0.54 6.05e-27 IgG glycosylation; LIHC cis rs4073582 0.595 rs555360 chr11:65960061 T/C cg14036092 chr11:66035641 RAB1B -0.43 -6.33 -0.32 7.66e-10 Gout; LIHC cis rs7552404 0.731 rs1689275 chr1:76409655 T/C cg10523679 chr1:76189770 ACADM -0.58 -6.84 -0.35 3.59e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.27 0.37 2.44e-12 Prudent dietary pattern; LIHC cis rs7726839 0.561 rs3915384 chr5:573395 G/T cg09021430 chr5:549028 NA -0.4 -8.77 -0.43 8.65e-17 Obesity-related traits; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg21448741 chr8:58168803 NA 0.36 6.5 0.33 2.8e-10 Developmental language disorder (linguistic errors); LIHC cis rs6502050 0.835 rs56095560 chr17:80151304 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.79 -0.3 1.56e-8 Life satisfaction; LIHC cis rs6502050 0.635 rs11867440 chr17:80147185 A/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.78 -0.3 1.64e-8 Life satisfaction; LIHC cis rs77633900 0.881 rs80003765 chr15:76657075 T/A cg21673338 chr15:77095150 SCAPER -0.53 -5.93 -0.31 7.22e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs2839186 0.814 rs12482209 chr21:47664275 C/G cg09417038 chr21:47716443 C21orf57 0.46 6.86 0.35 3.2e-11 Testicular germ cell tumor; LIHC cis rs7027203 1.000 rs13288708 chr9:96509653 T/C cg14598338 chr9:96623480 NA 0.31 6.07 0.31 3.43e-9 DNA methylation (variation); LIHC cis rs16854884 0.657 rs13078840 chr3:143700753 A/G cg06585982 chr3:143692056 C3orf58 0.57 7.53 0.38 4.44e-13 Economic and political preferences (feminism/equality); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg04904834 chr1:179851103 TOR1AIP1 0.4 6.1 0.31 2.87e-9 Morning vs. evening chronotype; LIHC cis rs6450176 1.000 rs4334836 chr5:53300835 T/C ch.5.1024479R chr5:53302184 ARL15 -0.81 -14.69 -0.62 3.22e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs7762018 0.770 rs3823466 chr6:170189926 C/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.63 0.34 1.3e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs922107 0.967 rs922104 chr1:90041899 C/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.77 -0.39 9.52e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs35110281 0.782 rs6518309 chr21:45047992 C/A cg21573476 chr21:45109991 RRP1B -0.56 -10.05 -0.48 5.43e-21 Mean corpuscular volume; LIHC cis rs11122272 0.735 rs2474630 chr1:231535335 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.18e-23 Hemoglobin concentration; LIHC cis rs11105298 0.891 rs10858872 chr12:89872932 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.54 -0.38 4.24e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10791097 0.694 rs61910787 chr11:130744473 G/A cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs295137 0.836 rs1217429 chr2:201094151 G/T cg23649088 chr2:200775458 C2orf69 0.49 6.79 0.34 5e-11 Asthma (bronchodilator response); LIHC cis rs7769051 0.522 rs3736725 chr6:133095172 A/G cg22852734 chr6:133119734 C6orf192 0.89 7.13 0.36 6.2e-12 Type 2 diabetes nephropathy; LIHC cis rs6545883 0.965 rs3771258 chr2:61764140 C/T cg14146966 chr2:61757674 XPO1 0.47 8.18 0.4 5.8e-15 Tuberculosis; LIHC cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg21724239 chr8:58056113 NA 0.5 6.68 0.34 9.98e-11 Developmental language disorder (linguistic errors); LIHC cis rs6089829 0.962 rs6062778 chr20:61663959 A/G cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.24 0.36 3e-12 Height; LIHC cis rs7523273 0.565 rs34355011 chr1:207887322 T/G cg22525895 chr1:207977042 MIR29B2 0.52 7.72 0.39 1.33e-13 Schizophrenia; LIHC cis rs9905704 0.647 rs11659035 chr17:56966052 C/T cg05425664 chr17:57184151 TRIM37 -0.44 -6.15 -0.32 2.19e-9 Testicular germ cell tumor; LIHC cis rs4660306 0.961 rs4660868 chr1:45986497 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.67 -0.34 1.02e-10 Homocysteine levels; LIHC cis rs2120019 0.638 rs12050628 chr15:75333494 G/A cg17294928 chr15:75287854 SCAMP5 0.71 10.91 0.51 5.6e-24 Blood trace element (Zn levels); LIHC cis rs9393692 0.905 rs7747133 chr6:26293470 C/T cg13736514 chr6:26305472 NA -0.37 -6.2 -0.32 1.63e-9 Educational attainment; LIHC cis rs988712 0.705 rs4923457 chr11:27648580 A/T cg18117895 chr11:27722066 BDNF 0.45 6.2 0.32 1.63e-9 Obesity; LIHC cis rs2073300 1.000 rs6132622 chr20:23442240 A/T cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8062405 0.755 rs17640009 chr16:28595700 A/G cg07382826 chr16:28625726 SULT1A1 0.5 7.86 0.39 5.17e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10751667 0.600 rs11246377 chr11:999796 G/T cg06064525 chr11:970664 AP2A2 -0.44 -10.79 -0.5 1.53e-23 Alzheimer's disease (late onset); LIHC cis rs7572733 0.534 rs700667 chr2:198677508 T/C cg03934865 chr2:198174659 NA 0.45 6.56 0.33 1.97e-10 Dermatomyositis; LIHC cis rs2997447 0.761 rs55815920 chr1:26457662 A/C cg19633962 chr1:26362018 EXTL1 -0.65 -5.76 -0.3 1.87e-8 QRS complex (12-leadsum); LIHC cis rs644799 0.542 rs10831415 chr11:95466159 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.52 6.59 0.34 1.7e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9733 0.519 rs1336900 chr1:150679033 C/T cg17724175 chr1:150552817 MCL1 0.47 9.74 0.47 5.99e-20 Tonsillectomy; LIHC cis rs568617 0.626 rs78028320 chr11:65582015 G/A cg04055107 chr11:65626734 MUS81;CFL1 0.52 6.34 0.32 7.2e-10 Crohn's disease; LIHC cis rs2180341 0.804 rs6902233 chr6:127555963 A/G cg27446573 chr6:127587934 RNF146 1.02 14.32 0.61 9.09e-37 Breast cancer; LIHC cis rs1670533 1.000 rs2045068 chr4:1052212 G/A cg27284194 chr4:1044797 NA 0.61 9.14 0.44 5.63e-18 Recombination rate (females); LIHC cis rs611744 0.810 rs619227 chr8:109215100 C/A cg21045802 chr8:109455806 TTC35 0.58 9.69 0.46 8.63e-20 Dupuytren's disease; LIHC cis rs7017697 1.000 rs10092772 chr8:19686385 A/T cg03894339 chr8:19674705 INTS10 -0.49 -7.93 -0.39 3.07e-14 Breast cancer; LIHC cis rs2180341 0.960 rs6913424 chr6:127707010 A/C cg27446573 chr6:127587934 RNF146 1.02 16.27 0.66 1.67e-44 Breast cancer; LIHC cis rs9916302 0.904 rs7208274 chr17:37513796 C/T cg07936489 chr17:37558343 FBXL20 0.84 13.6 0.59 5.67e-34 Glomerular filtration rate (creatinine); LIHC cis rs611744 0.538 rs59930666 chr8:109262296 T/C cg18478394 chr8:109455254 TTC35 0.37 6.26 0.32 1.15e-9 Dupuytren's disease; LIHC cis rs908922 0.676 rs2105117 chr1:152484129 G/A cg20991723 chr1:152506922 NA 0.53 9.06 0.44 1.05e-17 Hair morphology; LIHC cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg10802521 chr3:52805072 NEK4 0.35 5.73 0.3 2.15e-8 Bipolar disorder; LIHC trans rs1552244 0.515 rs67342818 chr3:10166406 G/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs9457247 0.668 rs2236313 chr6:167360389 C/T cg12798992 chr6:167411361 FGFR1OP 0.39 6.14 0.32 2.28e-9 Crohn's disease; LIHC cis rs4808199 1.000 rs17288409 chr19:19504167 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.42 6.0 0.31 4.93e-9 Nonalcoholic fatty liver disease; LIHC cis rs2303759 0.918 rs10405465 chr19:49869298 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 9.02 0.44 1.39e-17 Multiple sclerosis; LIHC cis rs7917772 0.582 rs10786696 chr10:104378134 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.03e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9457247 0.534 rs1130033 chr6:167385623 C/T cg12798992 chr6:167411361 FGFR1OP 0.47 7.3 0.37 2.04e-12 Crohn's disease; LIHC cis rs1865760 0.963 rs1540273 chr6:25924158 T/C cg17691542 chr6:26056736 HIST1H1C 0.4 6.09 0.31 3.09e-9 Height; LIHC cis rs4713118 0.868 rs9468220 chr6:27732976 A/G cg20933634 chr6:27740509 NA -0.46 -5.94 -0.31 7.2e-9 Parkinson's disease; LIHC cis rs72772090 0.634 rs17402639 chr5:96107005 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.63 -7.08 -0.36 8.02e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs875971 1.000 rs1544549 chr7:66090663 T/A cg18252515 chr7:66147081 NA 0.45 6.47 0.33 3.42e-10 Aortic root size; LIHC cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg04267008 chr7:1944627 MAD1L1 -0.69 -11.26 -0.52 3.17e-25 Bipolar disorder and schizophrenia; LIHC cis rs7412746 0.597 rs868751 chr1:150669414 T/G cg17724175 chr1:150552817 MCL1 0.5 10.07 0.48 4.53e-21 Melanoma; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg10553204 chr2:20871195 GDF7 0.39 7.9 0.39 3.97e-14 Abdominal aortic aneurysm; LIHC cis rs6584283 0.846 rs10883370 chr10:101291472 T/C cg06854084 chr10:101292507 NKX2-3 -0.33 -6.13 -0.31 2.44e-9 Ulcerative colitis; LIHC cis rs6570726 0.791 rs9403730 chr6:145907233 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.25 -0.32 1.24e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg10802521 chr3:52805072 NEK4 0.44 7.5 0.38 5.37e-13 Bipolar disorder; LIHC cis rs11690935 0.550 rs62183769 chr2:172838074 A/C cg13550731 chr2:172543902 DYNC1I2 0.43 6.44 0.33 4.02e-10 Schizophrenia; LIHC cis rs611744 0.647 rs579162 chr8:109254842 A/G cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs910316 0.935 rs175448 chr14:75591071 G/A cg08847533 chr14:75593920 NEK9 -0.9 -19.49 -0.73 2.02e-57 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20228115 chr3:167813730 GOLIM4 0.43 6.23 0.32 1.34e-9 Lung function (FEV1/FVC); LIHC cis rs2286885 1.000 rs10733678 chr9:129242280 G/A cg15282417 chr9:129245246 FAM125B 0.41 6.77 0.34 5.52e-11 Intraocular pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27574168 chr18:54318782 WDR7 0.51 7.58 0.38 3.34e-13 Cognitive function; LIHC cis rs35110281 0.782 rs2246602 chr21:45064296 C/A cg04455712 chr21:45112962 RRP1B 0.48 8.22 0.41 4.35e-15 Mean corpuscular volume; LIHC cis rs35883536 0.626 rs12135243 chr1:101092955 G/A cg14515779 chr1:101123966 NA 0.55 7.59 0.38 3.12e-13 Monocyte count; LIHC cis rs3540 0.513 rs2589974 chr15:90891566 C/T cg22089800 chr15:90895588 ZNF774 -0.64 -8.93 -0.43 2.72e-17 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2075165 1.000 rs2075165 chr1:156215899 G/A cg07234388 chr1:156261841 TMEM79 0.52 8.93 0.44 2.59e-17 Tonsillectomy; LIHC cis rs739401 0.588 rs10219272 chr11:3020789 G/A cg25174290 chr11:3078921 CARS 0.59 9.0 0.44 1.64e-17 Longevity; LIHC cis rs769267 0.965 rs4808937 chr19:19398005 A/G cg03709012 chr19:19516395 GATAD2A 0.94 15.76 0.65 1.93e-42 Tonsillectomy; LIHC cis rs546131 0.614 rs7106579 chr11:34835502 C/A cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.59 -0.34 1.66e-10 Lung disease severity in cystic fibrosis; LIHC cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg06108461 chr20:60628389 TAF4 -0.6 -7.7 -0.38 1.47e-13 Obesity-related traits; LIHC cis rs2075371 1.000 rs1862051 chr7:133981021 G/A cg11752832 chr7:134001865 SLC35B4 0.52 7.83 0.39 6.08e-14 Mean platelet volume; LIHC cis rs600806 0.889 rs585545 chr1:109841662 A/T cg08911820 chr1:110026001 ATXN7L2 -0.52 -6.09 -0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs722599 0.683 rs7142898 chr14:75254310 A/T cg08847533 chr14:75593920 NEK9 0.54 8.16 0.4 6.38e-15 IgG glycosylation; LIHC cis rs6570726 1.000 rs444564 chr6:145859795 G/C cg23711669 chr6:146136114 FBXO30 0.53 9.21 0.45 3.29e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg12463550 chr7:65579703 CRCP 0.66 6.92 0.35 2.18e-11 Diabetic kidney disease; LIHC cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg02951883 chr7:2050386 MAD1L1 -0.51 -7.73 -0.39 1.22e-13 Bipolar disorder and schizophrenia; LIHC cis rs1144333 1.000 rs12410724 chr1:76459134 A/G cg22875332 chr1:76189707 ACADM 0.4 6.27 0.32 1.11e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg00656387 chr3:40428638 ENTPD3 0.5 8.29 0.41 2.68e-15 Renal cell carcinoma; LIHC cis rs2760061 0.598 rs2796056 chr1:228122901 G/A cg01200585 chr1:228362443 C1orf69 -0.4 -5.95 -0.31 6.54e-9 Diastolic blood pressure; LIHC cis rs1707322 0.964 rs6675259 chr1:46502295 G/A cg06784218 chr1:46089804 CCDC17 -0.39 -6.85 -0.35 3.47e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9611565 0.512 rs139560 chr22:42194962 A/G cg03806693 chr22:41940476 POLR3H -0.99 -10.54 -0.5 1.15e-22 Vitiligo; LIHC cis rs1023500 0.596 rs133352 chr22:42434022 C/A cg15557168 chr22:42548783 NA -0.42 -6.62 -0.34 1.36e-10 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13673319 chr1:174968334 CACYBP 0.45 6.85 0.35 3.53e-11 Cognitive function; LIHC trans rs6732426 0.792 rs3901678 chr2:43587451 A/C cg10773526 chr4:143327279 INPP4B -0.35 -6.1 -0.31 2.93e-9 Hair morphology; LIHC cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg18225595 chr11:63971243 STIP1 0.66 8.28 0.41 2.87e-15 Mean platelet volume; LIHC cis rs35110281 0.720 rs162393 chr21:44942692 G/A cg04455712 chr21:45112962 RRP1B 0.46 7.72 0.39 1.27e-13 Mean corpuscular volume; LIHC cis rs17125944 0.556 rs11625479 chr14:53354172 A/C cg00686598 chr14:53173677 PSMC6 -0.78 -8.8 -0.43 6.93e-17 Alzheimer's disease (late onset); LIHC trans rs7246657 0.943 rs7255996 chr19:37971699 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.24e-10 Coronary artery calcification; LIHC cis rs2050392 0.767 rs10763787 chr10:30700753 G/A cg25182066 chr10:30743637 MAP3K8 0.6 9.48 0.46 4.52e-19 Inflammatory bowel disease; LIHC trans rs1945213 0.694 rs11227181 chr11:55856053 C/T cg03929089 chr4:120376271 NA 0.53 6.87 0.35 3.01e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs6964587 1.000 rs7781066 chr7:91691946 G/T cg17063962 chr7:91808500 NA 1.01 19.31 0.72 1.04e-56 Breast cancer; LIHC trans rs116095464 0.614 rs10067482 chr5:219328 T/G cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08584230 chr13:113666091 MCF2L 0.44 6.89 0.35 2.62e-11 Calcium levels; LIHC trans rs3780486 0.713 rs3780489 chr9:33129844 G/T cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs1499614 1.000 rs1267817 chr7:66110040 G/T cg05590025 chr7:65112418 INTS4L2 -0.55 -5.87 -0.3 1.02e-8 Gout; LIHC cis rs7192750 0.586 rs2335714 chr16:71897926 A/G cg06353428 chr16:71660113 MARVELD3 0.79 8.9 0.43 3.23e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg23982607 chr1:1823379 GNB1 -0.75 -15.36 -0.64 7.53e-41 Body mass index; LIHC cis rs55783344 1.000 rs3999410 chr12:121445427 G/A cg02403541 chr12:121454288 C12orf43 -0.71 -5.73 -0.3 2.2e-8 Type 2 diabetes; LIHC trans rs1005277 0.579 rs1780139 chr10:38503018 C/T cg27523141 chr10:43048294 ZNF37B 0.38 6.51 0.33 2.66e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg06481639 chr22:41940642 POLR3H -0.72 -7.25 -0.36 2.88e-12 Vitiligo; LIHC cis rs9814567 1.000 rs13081688 chr3:134259954 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg05590025 chr7:65112418 INTS4L2 -0.58 -6.42 -0.33 4.57e-10 Diabetic kidney disease; LIHC cis rs11711311 0.955 rs10934241 chr3:113394705 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.4 6.76 0.34 5.95e-11 IgG glycosylation; LIHC cis rs7666738 0.578 rs1989109 chr4:98881246 T/A cg05340658 chr4:99064831 C4orf37 0.67 12.33 0.55 3.73e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs3096299 0.933 rs2965823 chr16:89454924 G/A cg06640241 chr16:89574553 SPG7 0.64 10.47 0.49 1.89e-22 Multiple myeloma (IgH translocation); LIHC cis rs2576037 0.501 rs557661 chr18:44365657 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.46 -6.77 -0.34 5.77e-11 Personality dimensions; LIHC cis rs2839627 0.598 rs56098337 chr21:44271365 G/T cg03543861 chr21:44258195 NA 0.53 8.63 0.42 2.29e-16 Information processing speed; LIHC cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.02 0.44 1.38e-17 Platelet count; LIHC cis rs2228479 0.717 rs9282682 chr16:89805794 A/G cg00800038 chr16:89945340 TCF25 -0.62 -9.28 -0.45 1.94e-18 Skin colour saturation; LIHC cis rs10911251 0.528 rs10911265 chr1:183115071 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.51e-22 Colorectal cancer; LIHC cis rs6570726 0.791 rs9399558 chr6:145911730 T/C cg23711669 chr6:146136114 FBXO30 0.73 12.2 0.55 1.17e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs8016982 0.674 rs8004096 chr14:81701082 T/G cg01989461 chr14:81687754 GTF2A1 0.63 12.49 0.56 9.32e-30 Schizophrenia; LIHC cis rs9549367 0.789 rs3850451 chr13:113905812 C/G cg00898013 chr13:113819073 PROZ -0.42 -7.17 -0.36 4.58e-12 Platelet distribution width; LIHC cis rs7103648 0.966 rs10838702 chr11:47410888 G/T cg20307385 chr11:47447363 PSMC3 0.96 16.31 0.66 1.25e-44 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs7474896 0.583 rs10740950 chr10:38003496 C/T cg25427524 chr10:38739819 LOC399744 -0.5 -7.33 -0.37 1.63e-12 Obesity (extreme); LIHC cis rs459571 0.959 rs2810491 chr9:136923331 C/T cg13789015 chr9:136890014 NCRNA00094 -0.43 -7.73 -0.39 1.2e-13 Platelet distribution width; LIHC cis rs6442522 0.867 rs12637268 chr3:15500248 T/C cg16303742 chr3:15540471 COLQ 0.5 8.34 0.41 1.86e-15 Uric acid levels; LIHC cis rs9549328 0.800 rs9549617 chr13:113628070 C/A cg04958157 chr13:113748321 MCF2L -0.35 -5.74 -0.3 2.09e-8 Systolic blood pressure; LIHC cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg25894440 chr7:65020034 NA 0.53 6.12 0.31 2.53e-9 Diabetic kidney disease; LIHC cis rs2369473 1 rs2369473 chr1:160210727 C/A cg02974968 chr1:160236444 NA -0.38 -7.79 -0.39 7.83e-14 Squamous cell lung carcinoma; LIHC cis rs9399135 0.933 rs9389262 chr6:135376409 G/T cg22676075 chr6:135203613 NA 0.42 6.66 0.34 1.11e-10 Red blood cell count; LIHC cis rs4925386 0.681 rs2427294 chr20:60927257 G/A cg06026331 chr20:60912101 LAMA5 0.61 8.98 0.44 1.89e-17 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs17376456 0.877 rs13153245 chr5:93374891 G/A cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs3812111 0.676 rs958738 chr6:116470561 A/G cg08036074 chr6:116424633 NT5DC1 -0.48 -8.06 -0.4 1.31e-14 Age-related macular degeneration; LIHC cis rs1355223 0.552 rs2421743 chr11:34882840 C/T cg24088639 chr11:34937564 PDHX;APIP -0.38 -5.96 -0.31 6.21e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2842992 0.747 rs733319 chr6:160221475 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.52 9.03 0.44 1.27e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs7772486 0.875 rs7761033 chr6:146356106 C/T cg23711669 chr6:146136114 FBXO30 0.66 11.76 0.54 4.95e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs9911578 1.000 rs3744108 chr17:56585872 G/C cg05425664 chr17:57184151 TRIM37 0.57 8.38 0.41 1.4e-15 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg00149659 chr3:10157352 C3orf10 0.61 6.71 0.34 7.86e-11 Alzheimer's disease; LIHC cis rs6545883 0.895 rs2256617 chr2:61679924 A/G cg15711740 chr2:61764176 XPO1 -0.43 -6.03 -0.31 4.19e-9 Tuberculosis; LIHC cis rs9457247 0.765 rs9457251 chr6:167426707 T/C cg23791538 chr6:167370224 RNASET2 -0.51 -7.94 -0.39 2.89e-14 Crohn's disease; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs7089973 0.604 rs11196942 chr10:116596872 G/A cg23260525 chr10:116636907 FAM160B1 0.39 7.62 0.38 2.52e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg17971929 chr21:40555470 PSMG1 0.84 10.05 0.48 5.24e-21 Cognitive function; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg11073931 chr20:57269626 NPEPL1 0.44 6.31 0.32 8.55e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs875971 0.965 rs7794930 chr7:65778546 A/C cg18876405 chr7:65276391 NA -0.36 -6.47 -0.33 3.31e-10 Aortic root size; LIHC cis rs1018836 0.886 rs4734246 chr8:91569028 A/C cg16814680 chr8:91681699 NA -0.61 -9.75 -0.47 5.44e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs34779708 0.897 rs9665538 chr10:35461038 T/C cg03585969 chr10:35415529 CREM 0.85 12.82 0.57 5.2e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10242455 0.702 rs45448997 chr7:99041598 G/C cg18809830 chr7:99032528 PTCD1 -0.82 -6.37 -0.33 5.95e-10 Blood metabolite levels; LIHC trans rs877282 0.898 rs12356709 chr10:763365 A/G cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs2832077 0.527 rs2250141 chr21:30241984 A/T cg24692254 chr21:30365293 RNF160 0.44 6.66 0.34 1.12e-10 Cognitive test performance; LIHC cis rs3744061 0.520 rs4322697 chr17:74648642 C/T cg02128979 chr17:74682217 MXRA7 0.33 5.82 0.3 1.33e-8 Retinal arteriolar caliber; LIHC cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg26939375 chr7:64535504 NA -0.47 -7.04 -0.36 1.08e-11 Calcium levels; LIHC cis rs2180341 0.694 rs2875972 chr6:127585522 T/C cg27446573 chr6:127587934 RNF146 0.71 10.74 0.5 2.28e-23 Breast cancer; LIHC cis rs2933343 0.700 rs1680788 chr3:128625318 C/T cg25356066 chr3:128598488 ACAD9 0.53 7.47 0.37 6.95e-13 IgG glycosylation; LIHC cis rs4423214 1.000 rs2040323 chr11:71172783 A/C cg05163923 chr11:71159392 DHCR7 0.84 12.57 0.56 4.6e-30 Vitamin D levels; LIHC trans rs62103177 0.513 rs9945153 chr18:77598450 C/T cg05926928 chr17:57297772 GDPD1 1.23 13.26 0.58 1.14e-32 Opioid sensitivity; LIHC cis rs2404602 0.716 rs12917430 chr15:76674360 T/C cg03037974 chr15:76606532 NA 0.8 16.71 0.67 2.93e-46 Blood metabolite levels; LIHC cis rs96067 0.740 rs10752586 chr1:36614713 C/G cg24686825 chr1:36642396 MAP7D1 -0.49 -6.73 -0.34 7.04e-11 Corneal structure; LIHC cis rs317689 0.918 rs610192 chr12:69739941 T/C cg20891283 chr12:69753455 YEATS4 0.69 10.73 0.5 2.45e-23 Response to diuretic therapy; LIHC cis rs8114671 0.562 rs6087653 chr20:33522054 T/C cg07148914 chr20:33460835 GGT7 0.64 9.68 0.46 9.72e-20 Height; LIHC cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.0 -0.35 1.4e-11 Bipolar disorder; LIHC cis rs9393692 0.645 rs766406 chr6:26319588 G/T cg00631329 chr6:26305371 NA -0.51 -8.0 -0.4 1.93e-14 Educational attainment; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg11598736 chr3:195384522 SDHAP2 -0.72 -8.58 -0.42 3.47e-16 Lung disease severity in cystic fibrosis; LIHC cis rs2576037 0.623 rs2571000 chr18:44580347 G/A cg19077165 chr18:44547161 KATNAL2 0.48 7.06 0.36 9.15e-12 Personality dimensions; LIHC cis rs921968 0.643 rs645796 chr2:219389236 A/G cg18887096 chr2:219472410 PLCD4 0.36 6.46 0.33 3.52e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs11673344 0.542 rs1667380 chr19:37492750 C/T cg27390819 chr19:37464633 NA -0.47 -6.26 -0.32 1.13e-9 Obesity-related traits; LIHC trans rs4843747 0.519 rs12599755 chr16:88107006 A/G cg26811252 chr16:29126840 RRN3P2 0.44 7.26 0.37 2.71e-12 Menopause (age at onset); LIHC trans rs1728785 0.748 rs889560 chr16:68605784 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs2228479 0.850 rs17226666 chr16:89835401 G/A cg04013166 chr16:89971882 TCF25 0.51 6.39 0.33 5.51e-10 Skin colour saturation; LIHC cis rs7208859 0.524 rs28760584 chr17:29141017 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9457247 0.765 rs9457259 chr6:167444281 C/T cg07741184 chr6:167504864 NA 0.31 7.09 0.36 7.82e-12 Crohn's disease; LIHC cis rs1580019 0.922 rs59938271 chr7:32484844 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.92 15.12 0.63 6.59e-40 Cognitive ability; LIHC cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg20891558 chr2:74357851 NA 0.83 16.96 0.68 2.94e-47 Gestational age at birth (maternal effect); LIHC cis rs9649213 0.614 rs4236537 chr7:97996593 T/C cg09267113 chr7:98030324 BAIAP2L1 -0.57 -10.12 -0.48 3.08e-21 Prostate cancer (SNP x SNP interaction); LIHC cis rs6754311 0.638 rs1011361 chr2:136553639 G/A cg15123519 chr2:136567270 LCT 0.44 8.68 0.42 1.63e-16 Mosquito bite size; LIHC cis rs6545883 0.718 rs2694624 chr2:61672313 C/A cg15711740 chr2:61764176 XPO1 -0.44 -6.06 -0.31 3.51e-9 Tuberculosis; LIHC trans rs3783890 1.000 rs61375994 chr14:93758073 G/A cg02802420 chr16:69363236 PDF;COG8 0.33 6.29 0.32 9.7e-10 Body mass index; LIHC trans rs7618501 0.602 rs2245365 chr3:50097319 C/A cg21659725 chr3:3221576 CRBN -0.69 -11.23 -0.52 3.87e-25 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.934 rs2216854 chr12:29423460 G/A cg14222432 chr12:29376421 FAR2 0.36 6.86 0.35 3.2e-11 QT interval; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06925236 chr11:68039653 C11orf24 0.47 6.96 0.35 1.76e-11 Pancreatic cancer; LIHC cis rs1707322 1.000 rs6675222 chr1:46326576 G/T cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8081395 0.836 rs2063353 chr17:57889192 T/G cg02344993 chr17:57696989 CLTC -0.46 -7.61 -0.38 2.77e-13 White blood cell count; LIHC trans rs11098499 0.691 rs12510133 chr4:120271344 A/C cg25214090 chr10:38739885 LOC399744 0.44 7.28 0.37 2.26e-12 Corneal astigmatism; LIHC cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg07424592 chr7:64974309 NA 0.87 9.34 0.45 1.26e-18 Diabetic kidney disease; LIHC cis rs57221529 0.766 rs58015612 chr5:580665 A/T cg09021430 chr5:549028 NA -0.45 -8.73 -0.43 1.14e-16 Lung disease severity in cystic fibrosis; LIHC cis rs8060686 0.545 rs12444313 chr16:68254404 A/C cg05110241 chr16:68378359 PRMT7 -0.61 -6.77 -0.34 5.71e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs6500602 0.702 rs6500606 chr16:4502514 A/G cg08645402 chr16:4508243 NA -0.45 -8.82 -0.43 5.76e-17 Schizophrenia; LIHC cis rs911119 0.955 rs6048946 chr20:23602307 G/T cg16589663 chr20:23618590 CST3 0.74 7.78 0.39 8.48e-14 Chronic kidney disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08585897 chr16:75680535 KARS;TERF2IP 0.44 6.69 0.34 9.36e-11 Longevity; LIHC cis rs35883536 0.967 rs9434126 chr1:101106981 A/G cg14515779 chr1:101123966 NA 0.64 12.18 0.55 1.36e-28 Monocyte count; LIHC cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg02951883 chr7:2050386 MAD1L1 -0.53 -7.88 -0.39 4.39e-14 Bipolar disorder and schizophrenia; LIHC trans rs9641123 0.639 rs2528521 chr7:93204544 C/T cg09745688 chr16:2908918 PRSS22 -0.37 -6.35 -0.32 6.93e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs2629540 0.765 rs7097254 chr10:126512248 A/C cg08799069 chr10:126477246 METTL10 -0.48 -8.06 -0.4 1.28e-14 Cocaine dependence; LIHC cis rs1506636 0.962 rs1019220 chr7:123365122 G/A cg03229431 chr7:123269106 ASB15 -0.62 -12.58 -0.56 4.45e-30 Plateletcrit;Platelet count; LIHC cis rs4819052 0.851 rs8133045 chr21:46658137 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.51 7.3 0.37 2.09e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6582630 0.555 rs7133706 chr12:38475465 G/A cg26384229 chr12:38710491 ALG10B -0.66 -9.43 -0.45 6.22e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs2952156 0.920 rs2517958 chr17:37838751 G/A cg00129232 chr17:37814104 STARD3 -0.56 -10.55 -0.5 9.98e-23 Asthma; LIHC cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs7618501 1.000 rs11130221 chr3:49819102 C/G cg21582582 chr3:182698605 DCUN1D1 0.53 6.9 0.35 2.56e-11 Intelligence (multi-trait analysis); LIHC cis rs10492096 0.947 rs11064227 chr12:6598043 A/G cg13857086 chr12:6580257 VAMP1 0.6 6.34 0.32 7.18e-10 Hip geometry; LIHC cis rs7700895 0.691 rs3777183 chr5:95263735 G/A cg10483112 chr5:95245456 ELL2 -0.38 -6.63 -0.34 1.33e-10 IgG glycosylation; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg11060661 chr22:24314208 DDT;DDTL 0.59 10.16 0.48 2.22e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2153535 0.542 rs9378553 chr6:8472632 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs9517320 0.967 rs6491430 chr13:99178276 G/A cg07423050 chr13:99094983 FARP1 0.35 5.78 0.3 1.68e-8 Longevity; LIHC cis rs8010715 1.000 rs8010715 chr14:24609147 T/C cg23112188 chr14:24563095 PCK2 -0.31 -6.1 -0.31 2.89e-9 IgG glycosylation; LIHC cis rs8067545 0.750 rs4925072 chr17:19956899 C/T cg13482628 chr17:19912719 NA -0.47 -7.85 -0.39 5.25e-14 Schizophrenia; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg11494091 chr17:61959527 GH2 0.35 5.8 0.3 1.5e-8 Height; LIHC cis rs9611565 0.512 rs139562 chr22:42196684 G/C cg06481639 chr22:41940642 POLR3H -0.61 -5.83 -0.3 1.27e-8 Vitiligo; LIHC trans rs10028773 0.568 rs6838457 chr4:120267367 A/G cg25214090 chr10:38739885 LOC399744 0.44 7.16 0.36 5.01e-12 Educational attainment; LIHC cis rs9896933 0.778 rs80243549 chr17:80821485 G/T cg20578329 chr17:80767326 TBCD -0.66 -6.14 -0.32 2.31e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs2033908 0.620 rs1440271 chr11:12852068 A/G cg25843174 chr11:12811716 TEAD1 -0.33 -7.67 -0.38 1.78e-13 Sitting height ratio; LIHC cis rs35160687 0.623 rs718292 chr2:86473740 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.39 -6.32 -0.32 8.36e-10 Night sleep phenotypes; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs2430307 0.556 rs3905501 chr7:76542080 C/T cg15770687 chr7:76625569 PMS2L11 -0.46 -5.74 -0.3 2.05e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs17666538 0.585 rs1669733 chr8:606696 C/T cg13264159 chr8:625131 ERICH1 0.58 6.3 0.32 9.18e-10 IgG glycosylation; LIHC cis rs965469 0.779 rs6037571 chr20:3334322 C/T cg25506879 chr20:3388711 C20orf194 -0.53 -6.54 -0.33 2.22e-10 IFN-related cytopenia; LIHC cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg12463550 chr7:65579703 CRCP 0.68 7.05 0.36 9.9e-12 Diabetic kidney disease; LIHC cis rs11148252 0.532 rs9526975 chr13:53255804 C/T cg12458913 chr13:53173898 NA 0.52 8.5 0.42 5.89e-16 Lewy body disease; LIHC cis rs3741798 1.000 rs55865572 chr12:12497333 T/C cg08615371 chr12:12503544 MANSC1 0.91 7.34 0.37 1.54e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs5769765 0.908 rs9616213 chr22:50317851 T/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.34 -0.45 1.28e-18 Schizophrenia; LIHC cis rs7116495 0.737 rs661290 chr11:71766014 A/G cg26138937 chr11:71823887 C11orf51 -1.27 -10.41 -0.49 3.03e-22 Severe influenza A (H1N1) infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02326931 chr13:37572901 ALG5 0.47 6.39 0.33 5.47e-10 Pancreatic cancer; LIHC cis rs12602486 1.000 rs79296687 chr17:42262067 C/T cg13607699 chr17:42295918 UBTF -0.78 -6.64 -0.34 1.24e-10 Glycated hemoglobin levels; LIHC cis rs7089973 0.604 rs2181563 chr10:116604344 T/C cg23260525 chr10:116636907 FAM160B1 0.39 7.76 0.39 9.83e-14 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs6684514 1.000 rs11264468 chr1:156274585 C/G cg16558208 chr1:156270281 VHLL 0.54 10.28 0.49 8.88e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs526231 0.819 rs366437 chr5:102605601 T/C cg05225461 chr5:102596755 C5orf30 0.38 5.93 0.31 7.22e-9 Primary biliary cholangitis; LIHC cis rs10838687 0.800 rs3729805 chr11:47352757 C/T cg26139080 chr11:47293733 MADD -0.42 -5.83 -0.3 1.27e-8 Proinsulin levels; LIHC trans rs804280 0.509 rs12719915 chr8:11786255 A/G cg23539780 chr8:10696689 PINX1 0.41 6.09 0.31 3.02e-9 Myopia (pathological); LIHC cis rs7412746 0.634 rs12409208 chr1:150860055 A/G cg15448220 chr1:150897856 SETDB1 0.41 6.34 0.32 7.18e-10 Melanoma; LIHC cis rs7659604 0.791 rs57316471 chr4:122663939 A/G cg19748678 chr4:122722346 EXOSC9 0.41 6.87 0.35 3.05e-11 Type 2 diabetes; LIHC cis rs921968 0.643 rs832799 chr2:219490111 C/A cg02985541 chr2:219472218 PLCD4 0.43 7.99 0.4 2.14e-14 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.645 rs1851857 chr11:49855589 A/C cg03929089 chr4:120376271 NA -0.84 -15.93 -0.65 3.87e-43 Height; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg03721293 chr16:90014378 DEF8 0.36 6.24 0.32 1.26e-9 Skin colour saturation; LIHC cis rs12479064 0.505 rs62153764 chr2:99818612 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -10.1 -0.48 3.69e-21 Chronic sinus infection; LIHC trans rs11098499 0.618 rs35265692 chr4:120325135 T/C cg25214090 chr10:38739885 LOC399744 0.59 9.6 0.46 1.82e-19 Corneal astigmatism; LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg20607798 chr8:58055168 NA 0.62 7.91 0.39 3.52e-14 Developmental language disorder (linguistic errors); LIHC cis rs12995491 0.569 rs6724281 chr2:88529531 T/G cg18490616 chr2:88469792 THNSL2 -0.63 -7.93 -0.39 3.15e-14 Response to metformin (IC50); LIHC cis rs400736 0.894 rs226253 chr1:8027706 T/C cg25007680 chr1:8021821 PARK7 0.61 9.64 0.46 1.25e-19 Response to antidepressants and depression; LIHC cis rs67478160 0.595 rs12879501 chr14:104272634 G/T cg08213375 chr14:104286397 PPP1R13B 0.65 12.86 0.57 3.97e-31 Schizophrenia; LIHC cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg06618935 chr21:46677482 NA 0.3 5.71 0.3 2.45e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs116095464 0.558 rs57335027 chr5:262907 A/G cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC trans rs1488564 1.000 rs1488564 chr3:173453868 A/G cg08935021 chr1:28832541 SNHG3-RCC1;SNHG3 0.43 6.07 0.31 3.31e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03157738 chr19:11308118 KANK2 0.46 6.87 0.35 3.01e-11 Pancreatic cancer; LIHC cis rs4713118 0.662 rs9357060 chr6:28024486 C/G cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs1865760 0.929 rs1436307 chr6:25939723 C/T cg12310025 chr6:25882481 NA -0.42 -6.34 -0.32 7.27e-10 Height; LIHC cis rs7508 0.511 rs208026 chr8:17878155 A/G cg01800426 chr8:17659068 MTUS1 -0.4 -6.08 -0.31 3.22e-9 Atrial fibrillation; LIHC cis rs80282103 0.764 rs12247779 chr10:1107957 T/G cg08668510 chr10:1095578 IDI1 0.69 6.7 0.34 8.81e-11 Glomerular filtration rate (creatinine); LIHC cis rs4409675 0.597 rs1000431 chr1:28225114 C/T cg23691781 chr1:28212827 C1orf38 0.32 7.75 0.39 1.08e-13 Corneal astigmatism; LIHC cis rs9309473 0.607 rs10196402 chr2:73572081 A/C cg20560298 chr2:73613845 ALMS1 -0.42 -6.5 -0.33 2.85e-10 Metabolite levels; LIHC trans rs783540 0.900 rs4778686 chr15:83310835 C/T cg18393722 chr15:85113863 UBE2QP1 -0.37 -6.42 -0.33 4.44e-10 Schizophrenia; LIHC cis rs9300255 0.507 rs1727302 chr12:123632930 G/A cg05973401 chr12:123451056 ABCB9 0.49 7.11 0.36 6.62e-12 Neutrophil percentage of white cells; LIHC cis rs4819052 0.851 rs4819040 chr21:46659762 T/C cg22633049 chr21:46681294 NA -0.35 -6.25 -0.32 1.24e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs734999 0.967 rs4486391 chr1:2513055 A/T cg18854424 chr1:2615690 NA 0.33 7.17 0.36 4.62e-12 Ulcerative colitis; LIHC cis rs11148252 0.500 rs342768 chr13:53208882 C/T cg00495681 chr13:53174319 NA 0.66 11.68 0.53 9.19e-27 Lewy body disease; LIHC cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg13607699 chr17:42295918 UBTF 0.44 7.1 0.36 7.46e-12 Total body bone mineral density; LIHC cis rs1580019 0.563 rs896137 chr7:32579345 G/T cg07520158 chr7:32535189 LSM5;AVL9 0.61 9.02 0.44 1.37e-17 Cognitive ability; LIHC cis rs10751667 0.961 rs7480178 chr11:927108 T/C cg10932868 chr11:921992 NA 0.35 6.57 0.33 1.93e-10 Alzheimer's disease (late onset); LIHC cis rs249954 0.512 rs703767 chr16:23661639 G/C cg01460202 chr16:23706506 ERN2 0.35 5.93 0.31 7.24e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7044106 0.664 rs7861679 chr9:123375589 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.51 -7.72 -0.39 1.31e-13 Hip circumference adjusted for BMI; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23434193 chr8:74884752 TCEB1 0.45 6.9 0.35 2.5e-11 Cognitive function; LIHC cis rs9296092 0.522 rs62405955 chr6:33527176 T/C cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs240764 0.817 rs239219 chr6:101116146 C/T cg09795085 chr6:101329169 ASCC3 0.52 7.4 0.37 1.06e-12 Neuroticism; LIHC cis rs6456156 0.565 rs6921588 chr6:167494397 G/T cg23791538 chr6:167370224 RNASET2 -0.64 -10.18 -0.48 1.98e-21 Primary biliary cholangitis; LIHC cis rs7917772 0.536 rs3961456 chr10:104425304 A/T cg22532475 chr10:104410764 TRIM8 0.41 7.3 0.37 2.03e-12 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9303401 0.614 rs17175663 chr17:57108437 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.02 0.58 9.58e-32 Cognitive test performance; LIHC cis rs986417 0.901 rs1884094 chr14:61016933 C/G cg27398547 chr14:60952738 C14orf39 0.66 7.5 0.38 5.66e-13 Gut microbiota (bacterial taxa); LIHC cis rs2070488 0.965 rs2366123 chr3:38493153 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC cis rs6867032 0.958 rs4505990 chr5:2015811 A/G cg26168224 chr5:2018326 NA 0.31 7.54 0.38 4.32e-13 Gut microbiome composition (winter); LIHC cis rs8072100 0.537 rs9912450 chr17:45402208 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.36 -5.71 -0.3 2.46e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg15586393 chr4:1244086 CTBP1;C4orf42 -0.43 -6.04 -0.31 3.97e-9 Longevity; LIHC cis rs4665809 0.941 rs41285975 chr2:26351144 T/C cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs7582180 0.663 rs10199518 chr2:100946041 G/A cg14675211 chr2:100938903 LONRF2 0.55 8.23 0.41 4.03e-15 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03076246 chr16:67906784 EDC4 0.39 6.74 0.34 6.63e-11 Cognitive function; LIHC cis rs7072216 0.763 rs10736129 chr10:100171571 C/T cg26618903 chr10:100175079 PYROXD2 0.39 6.25 0.32 1.22e-9 Metabolite levels; LIHC cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.31 0.45 1.56e-18 Electroencephalogram traits; LIHC cis rs911119 0.657 rs2104005 chr20:23630761 G/A cg16589663 chr20:23618590 CST3 0.67 6.32 0.32 7.98e-10 Chronic kidney disease; LIHC cis rs7106204 0.514 rs7126508 chr11:24255147 G/A ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.24e-27 Response to Homoharringtonine (cytotoxicity); LIHC trans rs11722228 0.539 rs62287552 chr4:10153197 C/T cg26043149 chr18:55253948 FECH 0.99 14.54 0.62 1.29e-37 Gout;Urate levels;Serum uric acid levels; LIHC cis rs13108904 0.901 rs7695691 chr4:1304632 A/G cg00684032 chr4:1343700 KIAA1530 0.37 6.09 0.31 3.07e-9 Obesity-related traits; LIHC cis rs826838 0.872 rs826878 chr12:39088837 A/T cg26384229 chr12:38710491 ALG10B -0.5 -7.91 -0.39 3.49e-14 Heart rate; LIHC trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg07332563 chr6:291687 DUSP22 -0.47 -6.79 -0.34 5.03e-11 Menopause (age at onset); LIHC cis rs9633740 0.945 rs6586030 chr10:82254047 C/T cg01528321 chr10:82214614 TSPAN14 -0.91 -10.15 -0.48 2.47e-21 Post bronchodilator FEV1; LIHC cis rs9420 0.961 rs11229148 chr11:57621460 A/T cg19752551 chr11:57585705 CTNND1 -0.5 -6.9 -0.35 2.53e-11 Schizophrenia; LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg09417038 chr21:47716443 C21orf57 0.45 7.02 0.35 1.24e-11 Testicular germ cell tumor; LIHC cis rs17270561 0.636 rs9393671 chr6:25789189 G/C cg17691542 chr6:26056736 HIST1H1C -0.44 -6.01 -0.31 4.75e-9 Iron status biomarkers; LIHC cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg21280719 chr6:42927975 GNMT -0.36 -7.84 -0.39 5.77e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs13191362 1.000 rs35723993 chr6:163008197 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs11098499 0.754 rs4443261 chr4:120249301 T/C cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.01e-25 Corneal astigmatism; LIHC cis rs735860 0.763 rs2817111 chr6:53125700 G/C cg10236188 chr6:53219634 NA -0.4 -7.29 -0.37 2.14e-12 Glaucoma; LIHC cis rs2153535 0.580 rs2184582 chr6:8447793 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs3770081 1.000 rs12620810 chr2:86391481 G/A cg01119172 chr2:86362222 SNORD94;PTCD3 0.43 6.21 0.32 1.51e-9 Facial emotion recognition (sad faces); LIHC trans rs3780486 0.846 rs4584234 chr9:33147479 G/A cg20290983 chr6:43655470 MRPS18A 1.04 21.39 0.76 4.96e-65 IgG glycosylation; LIHC cis rs7772486 0.875 rs6938972 chr6:146410608 G/A cg23711669 chr6:146136114 FBXO30 0.64 10.83 0.51 1.07e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs17253792 0.822 rs10151664 chr14:56029533 A/G cg24579896 chr14:56047964 C14orf33;KTN1 0.69 5.88 0.3 9.77e-9 Putamen volume; LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg14709524 chr16:89940631 TCF25 0.55 7.23 0.36 3.15e-12 Skin colour saturation; LIHC cis rs875971 0.638 rs35986979 chr7:66088990 G/A cg11764359 chr7:65958608 NA -0.72 -10.75 -0.5 2.11e-23 Aortic root size; LIHC cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg07414643 chr4:187882934 NA 0.24 6.17 0.32 1.93e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12477438 0.520 rs6542869 chr2:99783403 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.21 21.23 0.75 2.06e-64 Chronic sinus infection; LIHC cis rs9467773 0.626 rs6935803 chr6:26350495 A/G cg09904177 chr6:26538194 HMGN4 -0.37 -5.95 -0.31 6.82e-9 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs28756676 chr15:45540360 G/A cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC cis rs9486719 1.000 rs12208124 chr6:97027942 C/T cg06623918 chr6:96969491 KIAA0776 -0.7 -7.24 -0.36 3.06e-12 Migraine;Coronary artery disease; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg10217327 chr6:118973057 C6orf204 0.7 7.26 0.37 2.67e-12 Diastolic blood pressure; LIHC cis rs11971779 0.646 rs58682779 chr7:139084712 C/T cg07862535 chr7:139043722 LUC7L2 0.69 11.19 0.52 5.54e-25 Diisocyanate-induced asthma; LIHC cis rs2153535 0.580 rs7769020 chr6:8457724 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg04267008 chr7:1944627 MAD1L1 0.71 11.53 0.53 3.42e-26 Bipolar disorder and schizophrenia; LIHC cis rs4319547 1.000 rs6489156 chr12:123100397 C/T cg05707623 chr12:122985044 ZCCHC8 -0.58 -7.66 -0.38 1.89e-13 Body mass index; LIHC cis rs7582720 1.000 rs115396314 chr2:203721314 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.03 0.31 4.17e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs72960926 0.744 rs72954314 chr6:74939737 A/G cg07247405 chr1:2484626 LOC115110 0.53 6.38 0.33 5.78e-10 Metabolite levels (MHPG); LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg00656387 chr3:40428638 ENTPD3 -0.5 -8.54 -0.42 4.56e-16 Renal cell carcinoma; LIHC trans rs4820294 0.669 rs9622677 chr22:38054262 A/C cg19894588 chr14:64061835 NA -0.47 -7.44 -0.37 8.1e-13 Fat distribution (HIV); LIHC cis rs1451375 0.583 rs3779078 chr7:50610918 C/T cg14593290 chr7:50529359 DDC 0.62 9.68 0.46 9.37e-20 Malaria; LIHC cis rs9649213 0.593 rs7776638 chr7:97993506 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.24e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs6952808 0.771 rs10244946 chr7:1921068 A/G cg21782813 chr7:2030301 MAD1L1 -0.41 -6.9 -0.35 2.52e-11 Bipolar disorder and schizophrenia; LIHC cis rs9372253 0.818 rs2207360 chr6:110706337 G/C cg19196401 chr6:110721138 DDO -0.32 -6.49 -0.33 3.02e-10 Platelet distribution width; LIHC cis rs722599 0.683 rs10144860 chr14:75286426 T/C cg08847533 chr14:75593920 NEK9 0.53 8.17 0.4 6.15e-15 IgG glycosylation; LIHC cis rs1215050 0.791 rs155019 chr4:98759126 G/A cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg17554472 chr22:41940697 POLR3H 0.56 6.06 0.31 3.53e-9 Vitiligo; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16595246 chr2:48009933 MSH6 0.45 6.3 0.32 8.98e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2404602 0.647 rs11855296 chr15:77092962 C/T cg03037974 chr15:76606532 NA -0.6 -9.96 -0.47 1.14e-20 Blood metabolite levels; LIHC cis rs79976124 0.879 rs78012385 chr6:66618091 G/A cg07460842 chr6:66804631 NA 0.62 6.36 0.33 6.59e-10 Type 2 diabetes; LIHC cis rs6782228 0.606 rs9828893 chr3:128332925 T/C cg16766828 chr3:128327626 NA -0.41 -6.42 -0.33 4.54e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7020830 0.898 rs308523 chr9:37338785 C/T cg14294708 chr9:37120828 ZCCHC7 1.0 20.05 0.74 1.12e-59 Schizophrenia; LIHC cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg00684032 chr4:1343700 KIAA1530 -0.35 -5.79 -0.3 1.61e-8 Obesity-related traits; LIHC cis rs7100689 0.646 rs1047952 chr10:82126808 C/G cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs1008375 1.000 rs6854733 chr4:17640526 C/T cg16339924 chr4:17578868 LAP3 0.44 6.19 0.32 1.68e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs870825 0.616 rs6843185 chr4:185649878 A/C cg04058563 chr4:185651563 MLF1IP 0.67 7.2 0.36 3.79e-12 Blood protein levels; LIHC cis rs6840360 0.593 rs867800 chr4:152691470 T/C cg22705602 chr4:152727874 NA -0.4 -8.47 -0.42 7.54e-16 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg12516959 chr21:47718080 NA -0.36 -6.0 -0.31 4.99e-9 Testicular germ cell tumor; LIHC cis rs6964587 0.967 rs9656003 chr7:91766322 A/C cg17063962 chr7:91808500 NA 1.05 21.66 0.76 4.03e-66 Breast cancer; LIHC cis rs12134245 0.776 rs12124682 chr1:91995542 A/G cg07090678 chr1:91966139 CDC7 0.51 7.01 0.35 1.29e-11 Breast cancer; LIHC cis rs651907 0.535 rs34743741 chr3:101532448 C/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.82 -0.3 1.36e-8 Colorectal cancer; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg12379764 chr21:47803548 PCNT -0.57 -8.4 -0.41 1.18e-15 Testicular germ cell tumor; LIHC cis rs2842992 0.830 rs752779 chr6:160133957 G/A cg11366901 chr6:160182831 ACAT2 0.94 16.18 0.66 3.95e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs738322 0.839 rs133015 chr22:38572526 C/G cg25457927 chr22:38595422 NA -0.39 -9.61 -0.46 1.65e-19 Cutaneous nevi; LIHC trans rs1005277 0.602 rs1780141 chr10:38504299 T/C cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs597539 0.690 rs635529 chr11:68626294 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.72 9.78 0.47 4.59e-20 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1707322 1.000 rs11211243 chr1:46455433 G/C cg03146154 chr1:46216737 IPP 0.48 7.93 0.39 3.23e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs66573146 0.656 rs66905212 chr4:6949508 G/C cg07817883 chr1:32538562 TMEM39B 1.2 10.01 0.48 7.28e-21 Granulocyte percentage of myeloid white cells; LIHC cis rs6748734 0.817 rs10182575 chr2:241806690 C/T cg08694578 chr2:241835147 C2orf54 -0.52 -8.03 -0.4 1.55e-14 Urinary metabolites; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09920427 chr19:12777674 MORG1;MAN2B1 0.49 7.48 0.37 6.2800000000000005e-13 Pancreatic cancer; LIHC cis rs116979167 0.575 rs1728649 chr7:105170570 A/G cg19920283 chr7:105172520 RINT1 0.49 6.08 0.31 3.16e-9 Bipolar disorder (body mass index interaction); LIHC cis rs12602486 1.000 rs2285953 chr17:42268255 G/C cg13607699 chr17:42295918 UBTF -0.76 -6.42 -0.33 4.65e-10 Glycated hemoglobin levels; LIHC cis rs4700695 0.841 rs152996 chr5:65256506 A/G cg21114390 chr5:65439923 SFRS12 0.44 5.77 0.3 1.8e-8 Facial morphology (factor 19); LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg16132339 chr22:24313637 DDTL;DDT 0.7 12.83 0.57 5.08e-31 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12744310 0.887 rs12024263 chr1:41820949 A/G cg03962019 chr1:41807865 NA 0.39 6.18 0.32 1.86e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs8141529 1.000 rs132534 chr22:29299806 T/C cg02153584 chr22:29168773 CCDC117 -0.39 -5.95 -0.31 6.71e-9 Lymphocyte counts; LIHC cis rs6960043 0.818 rs6967891 chr7:15065074 T/C cg19272540 chr7:15055459 NA -0.25 -6.86 -0.35 3.18e-11 Type 2 diabetes; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.48 -6.76 -0.34 6.05e-11 Lymphocyte counts; LIHC cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg04317338 chr11:64019027 PLCB3 0.84 10.19 0.48 1.86e-21 Mean platelet volume; LIHC cis rs7089973 0.604 rs11196932 chr10:116584386 C/T cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1577917 0.959 rs12201739 chr6:86720739 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.82 -0.35 4.09e-11 Response to antipsychotic treatment; LIHC cis rs10911232 0.507 rs12037623 chr1:183000148 G/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7944735 0.508 rs4752783 chr11:47558220 G/A cg20307385 chr11:47447363 PSMC3 -0.54 -5.76 -0.3 1.91e-8 Intraocular pressure; LIHC cis rs2742417 0.603 rs2742448 chr3:45764246 C/T cg04837898 chr3:45731254 SACM1L 0.44 6.62 0.34 1.38e-10 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs2380220 0.574 rs7766765 chr6:95997362 G/A cg23517279 chr6:96025343 MANEA 0.57 6.3 0.32 9.19e-10 Behavioural disinhibition (generation interaction); LIHC trans rs11098499 0.739 rs7441137 chr4:120133221 G/T cg25214090 chr10:38739885 LOC399744 -0.38 -6.26 -0.32 1.12e-9 Corneal astigmatism; LIHC cis rs12887734 0.524 rs4906364 chr14:104214342 C/G cg01849466 chr14:104193079 ZFYVE21 -0.41 -6.18 -0.32 1.82e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs11165623 0.564 rs6593612 chr1:97002041 C/A cg10631902 chr5:14652156 NA -0.29 -6.62 -0.34 1.36e-10 Hip circumference;Waist circumference; LIHC cis rs763121 0.853 rs5750626 chr22:38977890 G/C cg06022373 chr22:39101656 GTPBP1 0.69 12.02 0.54 5.37e-28 Menopause (age at onset); LIHC cis rs801193 1.000 rs7783924 chr7:66209057 A/C cg18876405 chr7:65276391 NA 0.42 7.32 0.37 1.79e-12 Aortic root size; LIHC cis rs2303759 0.709 rs8102574 chr19:49828897 A/G cg22307029 chr19:49891270 CCDC155 0.57 8.81 0.43 6.63e-17 Multiple sclerosis; LIHC cis rs600806 0.850 rs115935180 chr1:109976775 C/G cg23091122 chr1:110024289 SYPL2 -0.5 -6.66 -0.34 1.09e-10 Intelligence (multi-trait analysis); LIHC cis rs12971120 0.947 rs8084410 chr18:72168486 T/C cg26446133 chr18:72167187 CNDP2 -0.79 -15.73 -0.65 2.38e-42 Refractive error; LIHC cis rs765787 0.530 rs11639403 chr15:45538350 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs67478160 0.679 rs8011109 chr14:104279974 G/A cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.5 -0.38 5.56e-13 Schizophrenia; LIHC cis rs7903847 0.642 rs11189204 chr10:99164394 C/T cg08345082 chr10:99160200 RRP12 -0.4 -6.91 -0.35 2.39e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs79149102 0.579 rs8034149 chr15:75311842 G/C cg15902774 chr15:75289873 SCAMP5 0.41 6.08 0.31 3.2e-9 Lung cancer; LIHC cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg00149659 chr3:10157352 C3orf10 0.68 7.2 0.36 3.97e-12 Alzheimer's disease; LIHC trans rs7674212 0.570 rs2126470 chr4:104061762 T/C cg16471864 chr4:38666270 KLF3;FLJ13197 -0.44 -6.13 -0.31 2.45e-9 Type 2 diabetes; LIHC cis rs67311347 0.577 rs1317217 chr3:40271697 T/G cg18306943 chr3:40428807 ENTPD3 0.38 6.36 0.33 6.38e-10 Renal cell carcinoma; LIHC cis rs7534824 0.507 rs7518380 chr1:101451262 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 7.63 0.38 2.34e-13 Refractive astigmatism; LIHC cis rs2404602 0.647 rs12440965 chr15:76958591 G/A cg23625390 chr15:77176239 SCAPER -0.54 -8.85 -0.43 4.9e-17 Blood metabolite levels; LIHC cis rs963731 0.522 rs297128 chr2:39298403 C/G cg04010122 chr2:39346883 SOS1 -0.68 -6.02 -0.31 4.46e-9 Corticobasal degeneration; LIHC cis rs7772486 0.840 rs2777478 chr6:146309117 T/C cg13319975 chr6:146136371 FBXO30 -0.39 -6.3 -0.32 9.41e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10911251 0.546 rs12034436 chr1:183114797 A/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.54 0.5 1.12e-22 Colorectal cancer; LIHC cis rs4820294 1.000 rs62236668 chr22:38063870 G/A cg26138144 chr22:38071188 LGALS1 0.75 13.96 0.6 2.28e-35 Fat distribution (HIV); LIHC cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.46 0.46 5.3e-19 Platelet count; LIHC cis rs763014 0.932 rs2269559 chr16:682297 T/C cg07343612 chr16:622815 PIGQ -0.86 -14.81 -0.63 1.06e-38 Height; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg14828511 chr1:107599125 PRMT6 0.41 6.0 0.31 4.95e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12249377 0.519 rs11186320 chr10:92576448 C/T cg14313238 chr10:92632228 RPP30 -0.38 -6.53 -0.33 2.39e-10 White matter microstructure (global fractional anisotropy); LIHC cis rs2439831 1.000 rs7173487 chr15:43750239 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.61 7.72 0.39 1.33e-13 Lung cancer in ever smokers; LIHC cis rs11758351 0.866 rs2022448 chr6:26207928 C/T cg16070018 chr6:26224392 HIST1H3E 0.48 6.53 0.33 2.32e-10 Gout;Renal underexcretion gout; LIHC cis rs7131987 0.801 rs962866 chr12:29434147 A/G cg14222432 chr12:29376421 FAR2 0.34 6.69 0.34 9.16e-11 QT interval; LIHC cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg05564831 chr3:52568323 NT5DC2 0.35 5.84 0.3 1.21e-8 Bipolar disorder; LIHC cis rs7647973 0.710 rs11130207 chr3:49611666 T/G cg03060546 chr3:49711283 APEH 0.62 6.96 0.35 1.76e-11 Menarche (age at onset); LIHC cis rs4728302 0.838 rs10224828 chr7:133591071 G/A cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs2180341 1.000 rs6903878 chr6:127638600 C/G cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs2153535 0.580 rs9392223 chr6:8468650 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.8 0.39 7.36e-14 Motion sickness; LIHC cis rs1691799 0.863 rs1168291 chr12:66732488 T/C cg16791601 chr12:66731901 HELB -0.57 -13.85 -0.6 6.39e-35 White blood cell count (basophil); LIHC cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg18404041 chr3:52824283 ITIH1 -0.51 -8.46 -0.42 8.17e-16 Electroencephalogram traits; LIHC cis rs26949 0.511 rs2898287 chr5:59884233 C/G cg02684056 chr5:59996105 DEPDC1B -0.39 -5.95 -0.31 6.54e-9 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg07092213 chr7:1199455 ZFAND2A -0.43 -6.33 -0.32 7.84e-10 Longevity;Endometriosis; LIHC cis rs9911578 0.835 rs723991 chr17:56482039 G/A cg05425664 chr17:57184151 TRIM37 0.57 8.19 0.41 5.15e-15 Intelligence (multi-trait analysis); LIHC cis rs739401 0.572 rs404629 chr11:3077025 A/G cg05729581 chr11:3078854 CARS -0.43 -5.83 -0.3 1.26e-8 Longevity; LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs6089584 0.566 rs6061963 chr20:60607480 C/G cg23262073 chr20:60523788 NA -0.29 -6.18 -0.32 1.87e-9 Body mass index; LIHC cis rs7587476 0.689 rs10498025 chr2:215749256 A/G cg04530015 chr2:215796436 ABCA12 -0.37 -5.91 -0.3 8.2e-9 Neuroblastoma; LIHC cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.82 7.77 0.39 9.04e-14 Platelet count; LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg02782426 chr3:40428986 ENTPD3 0.35 6.48 0.33 3.23e-10 Renal cell carcinoma; LIHC cis rs1707322 0.682 rs28490344 chr1:46197948 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2070433 0.500 rs9306156 chr21:47960493 T/C cg12379764 chr21:47803548 PCNT 0.62 9.64 0.46 1.32e-19 Lymphocyte counts; LIHC trans rs61931739 0.534 rs6488189 chr12:33995865 C/T cg26384229 chr12:38710491 ALG10B 0.49 6.95 0.35 1.83e-11 Morning vs. evening chronotype; LIHC cis rs9900497 0.569 rs2072327 chr17:19651482 G/T cg22552966 chr17:19620595 SLC47A2 -0.47 -10.29 -0.49 7.91e-22 Response to paliperidone in schizophrenia (CGI-S score); LIHC cis rs8064299 0.597 rs6501737 chr17:72780830 C/T cg25054828 chr17:72772726 NAT9;TMEM104 -0.7 -12.22 -0.55 9.79e-29 Monocyte count; LIHC cis rs1075232 0.826 rs12438813 chr15:31705913 C/T cg01030201 chr15:31746330 NA -0.86 -6.64 -0.34 1.22e-10 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.66 -0.56 2.17e-30 Alzheimer's disease; LIHC cis rs8180040 0.701 rs13066214 chr3:47033937 C/T cg16586182 chr3:47516702 SCAP -0.49 -8.84 -0.43 5.22e-17 Colorectal cancer; LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.54 0.38 4.19e-13 Prudent dietary pattern; LIHC trans rs1814175 0.817 rs10839397 chr11:49857074 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.13 0.36 6.13e-12 Height; LIHC cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg13395646 chr4:1353034 KIAA1530 -0.66 -9.5 -0.46 3.75e-19 Obesity-related traits; LIHC cis rs10883723 0.738 rs3781290 chr10:104244948 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.31 0.55 4.54e-29 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg24846343 chr22:24311635 DDTL 0.55 9.8 0.47 3.86e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10791097 0.694 rs10791103 chr11:130757161 G/A cg14779329 chr11:130786720 SNX19 0.42 6.41 0.33 4.72e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1801251 0.896 rs2305141 chr2:233684402 A/G cg08000102 chr2:233561755 GIGYF2 -0.74 -10.72 -0.5 2.54e-23 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06451949 chr17:48942959 NA 0.48 7.45 0.37 7.54e-13 Pancreatic cancer; LIHC cis rs2153535 0.580 rs6920779 chr6:8437624 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.99e-16 Motion sickness; LIHC cis rs7613875 0.641 rs6446194 chr3:50067298 T/A cg24110177 chr3:50126178 RBM5 0.54 8.81 0.43 6.41e-17 Body mass index; LIHC cis rs739401 0.572 rs389128 chr11:3083873 G/T cg25174290 chr11:3078921 CARS 0.68 10.4 0.49 3.49e-22 Longevity; LIHC cis rs1552244 0.554 rs34391585 chr3:9999208 G/C cg21531657 chr3:10005747 TMEM111 0.39 5.83 0.3 1.28e-8 Alzheimer's disease; LIHC cis rs11758351 0.660 rs2143345 chr6:26229148 C/T cg03854865 chr6:26224070 HIST1H3E 0.56 6.36 0.33 6.64e-10 Gout;Renal underexcretion gout; LIHC cis rs7772486 0.902 rs1331643 chr6:146398873 T/A cg05347473 chr6:146136440 FBXO30 0.34 5.82 0.3 1.34e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg10802521 chr3:52805072 NEK4 0.4 6.76 0.34 6.01e-11 Bipolar disorder; LIHC cis rs858239 0.571 rs6953020 chr7:23172132 T/C cg23682824 chr7:23144976 KLHL7 0.39 5.84 0.3 1.23e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs2303745 0.589 rs8103523 chr19:17398269 A/G cg02221750 chr19:17393354 ANKLE1 -0.41 -5.86 -0.3 1.07e-8 Systemic lupus erythematosus; LIHC cis rs9303401 1.000 rs9303401 chr17:56847945 C/T cg12560992 chr17:57184187 TRIM37 0.73 10.84 0.51 9.51e-24 Cognitive test performance; LIHC trans rs61931739 0.517 rs11513519 chr12:34075077 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.83 0.35 4.01e-11 Morning vs. evening chronotype; LIHC cis rs10927875 0.632 rs4661667 chr1:16162731 C/T cg07117364 chr1:16154769 NA -0.39 -7.03 -0.36 1.09e-11 Dilated cardiomyopathy; LIHC cis rs2153535 0.580 rs9379222 chr6:8514788 T/C cg21535247 chr6:8435926 SLC35B3 0.63 8.22 0.41 4.32e-15 Motion sickness; LIHC trans rs10242455 0.571 rs11972210 chr7:99206943 A/C cg09045935 chr12:6379348 NA 0.8 6.76 0.34 6.1e-11 Blood metabolite levels; LIHC cis rs826838 0.935 rs11168761 chr12:38997211 C/A cg26384229 chr12:38710491 ALG10B 0.92 12.12 0.55 2.31e-28 Heart rate; LIHC cis rs67311347 0.956 rs11714871 chr3:40428938 T/G cg00656387 chr3:40428638 ENTPD3 0.4 6.48 0.33 3.27e-10 Renal cell carcinoma; LIHC cis rs2777491 0.874 rs7161772 chr15:41611066 A/T cg18705301 chr15:41695430 NDUFAF1 -0.56 -8.28 -0.41 2.89e-15 Ulcerative colitis; LIHC cis rs2836974 0.666 rs12626405 chr21:40663121 G/T cg11890956 chr21:40555474 PSMG1 -0.49 -8.01 -0.4 1.86e-14 Cognitive function; LIHC cis rs7312933 0.584 rs7974654 chr12:42630466 C/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.95 0.39 2.73e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs965469 0.901 rs6037586 chr20:3368114 G/A cg25506879 chr20:3388711 C20orf194 -0.56 -6.69 -0.34 8.95e-11 IFN-related cytopenia; LIHC cis rs2153535 0.580 rs9393019 chr6:8462091 G/A cg21535247 chr6:8435926 SLC35B3 0.63 8.24 0.41 3.84e-15 Motion sickness; LIHC cis rs11758351 1.000 rs77957229 chr6:26185226 A/G cg16070018 chr6:26224392 HIST1H3E 0.62 7.5 0.38 5.6e-13 Gout;Renal underexcretion gout; LIHC cis rs600626 0.588 rs10793124 chr11:75452267 C/G cg24262691 chr11:75473276 NA 0.4 5.88 0.3 9.98e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs11758351 1.000 rs16891401 chr6:26202337 G/A cg03854865 chr6:26224070 HIST1H3E 0.62 6.86 0.35 3.24e-11 Gout;Renal underexcretion gout; LIHC cis rs2806561 0.765 rs605367 chr1:23518524 T/C cg12483005 chr1:23474871 LUZP1 0.44 6.94 0.35 2.01e-11 Height; LIHC cis rs425277 1.000 rs262651 chr1:2091397 A/G cg24578937 chr1:2090814 PRKCZ 0.5 9.12 0.44 6.5e-18 Height; LIHC cis rs2073300 1.000 rs61080017 chr20:23457569 A/G cg12062639 chr20:23401060 NAPB 0.78 9.7 0.46 8.37e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10504229 1.000 rs66479724 chr8:58188309 T/G cg20607798 chr8:58055168 NA 0.46 5.88 0.3 9.96e-9 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.680 rs11772026 chr7:139052589 T/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs12477438 0.605 rs4585080 chr2:99557327 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.57 -8.97 -0.44 1.94e-17 Chronic sinus infection; LIHC cis rs1043515 0.748 rs11653487 chr17:36942631 A/G cg20826740 chr17:37024042 NA -0.39 -6.68 -0.34 9.76e-11 Height; LIHC cis rs6540556 0.517 rs11807619 chr1:209881373 G/T cg05527609 chr1:210001259 C1orf107 -0.54 -7.56 -0.38 3.8e-13 Red blood cell count; LIHC cis rs3770081 1.000 rs3770066 chr2:86392350 A/T cg01119172 chr2:86362222 SNORD94;PTCD3 0.41 5.96 0.31 6.35e-9 Facial emotion recognition (sad faces); LIHC cis rs4788570 0.667 rs8053186 chr16:71790166 G/A cg06353428 chr16:71660113 MARVELD3 1.36 14.03 0.6 1.21e-35 Intelligence (multi-trait analysis); LIHC trans rs11039798 0.588 rs10838970 chr11:48606267 G/T cg15704280 chr7:45808275 SEPT13 0.57 6.34 0.32 7.24e-10 Axial length; LIHC cis rs11626933 1.000 rs4559843 chr14:90747488 T/C cg14092571 chr14:90743983 NA -0.9 -14.86 -0.63 6.84e-39 Gut microbiota (bacterial taxa); LIHC cis rs3540 0.576 rs1974519 chr15:91036460 A/G cg22089800 chr15:90895588 ZNF774 0.6 8.17 0.4 6.1e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs7224685 0.569 rs10521129 chr17:4008820 C/T cg09597638 chr17:3907349 NA 0.55 7.08 0.36 8.18e-12 Type 2 diabetes; LIHC cis rs2236918 0.932 rs2488471 chr1:242019831 T/C cg17736920 chr1:242011382 EXO1 0.6 8.72 0.43 1.19e-16 Menopause (age at onset); LIHC cis rs8014204 0.901 rs6574200 chr14:75364451 C/T cg08847533 chr14:75593920 NEK9 -0.37 -6.24 -0.32 1.28e-9 Caffeine consumption; LIHC cis rs16828019 0.777 rs12047657 chr1:41461513 G/C cg03387723 chr1:41708464 SCMH1 -0.45 -6.66 -0.34 1.07e-10 Intelligence (multi-trait analysis); LIHC cis rs13161895 0.591 rs12655422 chr5:179480825 C/A cg02702477 chr5:179499311 RNF130 0.89 11.71 0.53 7.31e-27 LDL cholesterol; LIHC trans rs66573146 0.831 rs67702333 chr4:6983040 C/G cg07817883 chr1:32538562 TMEM39B 1.1 9.18 0.44 4.1e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs6088590 0.561 rs6059918 chr20:33150503 C/T cg08999081 chr20:33150536 PIGU 0.69 13.8 0.6 9.3e-35 Coronary artery disease; LIHC cis rs9911578 0.757 rs117987711 chr17:57111269 A/C cg12560992 chr17:57184187 TRIM37 -0.81 -12.41 -0.56 1.93e-29 Intelligence (multi-trait analysis); LIHC cis rs12478296 0.748 rs10185596 chr2:243001029 C/A cg06360820 chr2:242988706 NA -0.76 -10.88 -0.51 6.99e-24 Obesity-related traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08664849 chr16:2546474 TBC1D24 -0.36 -6.13 -0.31 2.4e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs116095464 0.558 rs56342538 chr5:225796 T/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs12986413 1.000 rs12983458 chr19:2168612 A/G cg09261902 chr19:2140048 AP3D1 0.37 6.24 0.32 1.26e-9 Height; LIHC cis rs4919087 0.851 rs2297987 chr10:98989454 C/T cg25902810 chr10:99078978 FRAT1 -0.63 -9.03 -0.44 1.26e-17 Monocyte count; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg27432699 chr2:27873401 GPN1 -0.49 -7.07 -0.36 8.55e-12 Total body bone mineral density; LIHC cis rs6754311 0.731 rs12988076 chr2:136569848 C/A cg15123519 chr2:136567270 LCT 0.45 9.45 0.45 5.73e-19 Mosquito bite size; LIHC cis rs559928 0.606 rs78038516 chr11:63978067 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 8.2 0.41 4.96e-15 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7584330 0.554 rs56853932 chr2:238428327 T/C cg08992911 chr2:238395768 MLPH 0.52 6.34 0.32 7.29e-10 Prostate cancer; LIHC cis rs477895 0.713 rs11607165 chr11:63963947 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 9.65 0.46 1.17e-19 Mean platelet volume; LIHC trans rs875971 1.000 rs778696 chr7:65870813 C/G cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg10815395 chr12:49237807 DDX23 0.45 6.27 0.32 1.09e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg26668828 chr6:292823 DUSP22 -0.62 -8.66 -0.42 1.9e-16 Menopause (age at onset); LIHC cis rs13191362 1.000 rs67646369 chr6:163003233 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10454142 0.807 rs13399936 chr2:48654126 T/G cg15846641 chr2:48541264 FOXN2 0.46 6.06 0.31 3.54e-9 Sex hormone-binding globulin levels; LIHC cis rs4730250 0.707 rs80095766 chr7:106901394 G/T cg02696742 chr7:106810147 HBP1 -0.53 -6.28 -0.32 1.05e-9 Osteoarthritis; LIHC trans rs3758911 0.796 rs10890720 chr11:107206018 C/T cg21068293 chr15:74496576 STRA6 -0.27 -6.31 -0.32 8.86e-10 Coronary artery disease; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.69 9.97 0.47 9.89e-21 Lymphocyte counts; LIHC cis rs11122272 0.735 rs2790883 chr1:231532726 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.14e-23 Hemoglobin concentration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18906815 chr12:124996063 NCOR2 -0.4 -6.08 -0.31 3.26e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8014204 0.604 rs11159109 chr14:75389074 G/A cg08847533 chr14:75593920 NEK9 0.47 7.65 0.38 2.01e-13 Caffeine consumption; LIHC cis rs12477438 0.871 rs13396584 chr2:99611768 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.66 9.05 0.44 1.14e-17 Chronic sinus infection; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg07677032 chr17:61819896 STRADA 0.43 6.28 0.32 1.03e-9 Prudent dietary pattern; LIHC cis rs11971779 0.938 rs11981688 chr7:139088895 A/G cg07862535 chr7:139043722 LUC7L2 0.68 11.23 0.52 4.18e-25 Diisocyanate-induced asthma; LIHC cis rs798554 0.679 rs1636254 chr7:2885724 T/C cg13628971 chr7:2884303 GNA12 0.59 10.08 0.48 4.36e-21 Height; LIHC cis rs4919694 1.000 rs12253284 chr10:104665145 G/C cg04362960 chr10:104952993 NT5C2 0.78 7.9 0.39 3.79e-14 Arsenic metabolism; LIHC cis rs4407350 0.870 rs5764877 chr22:44915530 T/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.35 -0.32 6.82e-10 Intelligence (multi-trait analysis); LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg10553204 chr2:20871195 GDF7 -0.38 -7.02 -0.35 1.19e-11 Abdominal aortic aneurysm; LIHC cis rs875971 1.000 rs6961990 chr7:65888570 C/A cg18252515 chr7:66147081 NA -0.41 -5.76 -0.3 1.86e-8 Aortic root size; LIHC cis rs7412746 0.658 rs10305711 chr1:150802996 T/C cg18016565 chr1:150552671 MCL1 0.54 10.25 0.48 1.16e-21 Melanoma; LIHC cis rs2070433 0.500 rs2070435 chr21:47961711 C/T cg12379764 chr21:47803548 PCNT 0.61 9.19 0.44 4.04e-18 Lymphocyte counts; LIHC cis rs11098499 0.909 rs6842762 chr4:120398236 A/T cg09307838 chr4:120376055 NA 0.76 12.3 0.55 4.72e-29 Corneal astigmatism; LIHC cis rs4759375 1.000 rs28410096 chr12:123880862 T/C cg00376283 chr12:123451042 ABCB9 0.49 6.1 0.31 2.93e-9 HDL cholesterol; LIHC cis rs17125944 0.505 rs77137752 chr14:53230496 G/T cg00686598 chr14:53173677 PSMC6 1.2 15.24 0.64 2.21e-40 Alzheimer's disease (late onset); LIHC cis rs9929218 0.953 rs9927329 chr16:68750331 C/T cg01231543 chr16:68741748 NA 0.4 6.15 0.32 2.11e-9 Colorectal cancer; LIHC trans rs4718428 0.576 rs12698546 chr7:66266906 G/T cg10756647 chr7:56101905 PSPH 0.59 7.84 0.39 5.64e-14 Corneal structure; LIHC cis rs12594515 1.000 rs12906442 chr15:45985254 C/A cg01629716 chr15:45996671 NA 0.52 9.56 0.46 2.41e-19 Waist circumference;Weight; LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg20607798 chr8:58055168 NA 0.62 7.88 0.39 4.46e-14 Developmental language disorder (linguistic errors); LIHC cis rs9399135 0.967 rs9399129 chr6:135285148 C/A cg24558204 chr6:135376177 HBS1L 0.39 6.43 0.33 4.24e-10 Red blood cell count; LIHC cis rs9902453 0.765 rs3115087 chr17:28030267 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 12.2 0.55 1.15e-28 Coffee consumption (cups per day); LIHC cis rs875971 0.862 rs2420611 chr7:65999320 A/G cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.34e-9 Aortic root size; LIHC cis rs6960043 0.818 rs4719433 chr7:15065003 A/G cg19272540 chr7:15055459 NA -0.23 -6.35 -0.32 6.66e-10 Type 2 diabetes; LIHC cis rs6138458 1.000 rs2387361 chr20:24899905 C/T cg26195577 chr20:24973756 C20orf3 -1.09 -13.71 -0.6 2.13e-34 Blood protein levels; LIHC cis rs2108622 0.958 rs56340170 chr19:15981877 G/C cg13772218 chr19:15982569 NA 0.42 8.58 0.42 3.34e-16 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs10751667 0.600 rs10751665 chr11:941300 G/A cg10932868 chr11:921992 NA 0.38 7.34 0.37 1.59e-12 Alzheimer's disease (late onset); LIHC cis rs875971 0.862 rs778702 chr7:65864835 G/A cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs6466055 0.720 rs12668097 chr7:104996472 A/G cg04380332 chr7:105027541 SRPK2 0.35 6.65 0.34 1.19e-10 Schizophrenia; LIHC cis rs3008870 1.000 rs3008856 chr1:67387901 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.46 0.66 3.08e-45 Lymphocyte percentage of white cells; LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.58 8.85 0.43 4.79e-17 Height; LIHC cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg06634786 chr22:41940651 POLR3H -0.82 -8.94 -0.44 2.48e-17 Vitiligo; LIHC cis rs17270561 0.779 rs12210620 chr6:25884785 T/C cg17691542 chr6:26056736 HIST1H1C 0.83 9.78 0.47 4.26e-20 Iron status biomarkers; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05573837 chr3:42696434 ZBTB47 -0.54 -6.24 -0.32 1.32e-9 Systolic blood pressure; LIHC cis rs6582630 0.555 rs7969922 chr12:38529491 C/T cg13010199 chr12:38710504 ALG10B 0.43 5.87 0.3 1.03e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs5769765 0.542 rs5770720 chr22:50253101 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.58 5.81 0.3 1.44e-8 Schizophrenia; LIHC cis rs12477438 0.798 rs6705583 chr2:99602625 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.76 -11.41 -0.53 9.08e-26 Chronic sinus infection; LIHC cis rs7772486 0.875 rs2748498 chr6:146319166 C/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.3 -0.32 9.17e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2242116 0.734 rs4683294 chr3:46979013 C/G cg27129171 chr3:47204927 SETD2 -0.45 -6.98 -0.35 1.57e-11 Birth weight; LIHC cis rs1865760 0.602 rs9467662 chr6:26021327 G/A cg17691542 chr6:26056736 HIST1H1C 0.4 5.77 0.3 1.75e-8 Height; LIHC cis rs2274273 0.661 rs2147964 chr14:55564395 T/G cg01864836 chr14:55583639 NA -0.35 -6.64 -0.34 1.26e-10 Protein biomarker; LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.42 -0.41 1.02e-15 Lymphocyte counts; LIHC cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg19016816 chr7:1267987 NA 0.26 5.74 0.3 2.05e-8 Bipolar disorder and schizophrenia; LIHC cis rs4653663 0.533 rs12081218 chr1:225903098 G/A cg20799095 chr1:225924665 NA 0.38 5.76 0.3 1.9e-8 Neuroticism; LIHC cis rs861318 0.646 rs3768513 chr1:159012217 A/T cg11003133 chr1:159046391 AIM2 -0.35 -6.86 -0.35 3.32e-11 Obesity-related traits; LIHC cis rs8017423 0.967 rs11621045 chr14:90714003 C/T cg14092571 chr14:90743983 NA -0.38 -6.16 -0.32 2.09e-9 Mortality in heart failure; LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg14159672 chr1:205819179 PM20D1 0.86 12.54 0.56 6.28e-30 Menarche (age at onset); LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg09033563 chr22:24373618 LOC391322 -0.47 -6.71 -0.34 7.95e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03587843 chr5:1885516 NA 0.37 7.15 0.36 5.26e-12 Cognitive function; LIHC cis rs600806 0.813 rs4970759 chr1:109982213 C/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.08 -0.36 8.06e-12 Intelligence (multi-trait analysis); LIHC cis rs2645694 0.626 rs2645705 chr4:77830434 G/A cg06046430 chr4:77819534 ANKRD56 0.5 6.18 0.32 1.82e-9 Emphysema distribution in smoking; LIHC cis rs7131987 0.903 rs7974221 chr12:29399448 A/G cg16970926 chr12:29381810 FAR2 0.34 7.41 0.37 9.7e-13 QT interval; LIHC trans rs11165623 0.624 rs11165665 chr1:97007925 T/C cg10631902 chr5:14652156 NA -0.25 -6.28 -0.32 9.99e-10 Hip circumference;Waist circumference; LIHC cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg05552183 chr6:42928497 GNMT -0.71 -10.48 -0.49 1.74e-22 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg20887711 chr4:1340912 KIAA1530 -0.48 -7.45 -0.37 7.76e-13 Obesity-related traits; LIHC cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg05368731 chr17:41323189 NBR1 0.71 12.09 0.55 2.96e-28 Menopause (age at onset); LIHC cis rs6582630 0.502 rs11181210 chr12:38298069 G/A cg26384229 chr12:38710491 ALG10B 0.6 8.19 0.4 5.23e-15 Drug-induced liver injury (flucloxacillin); LIHC trans rs1814175 0.645 rs7395438 chr11:49877379 G/T cg03929089 chr4:120376271 NA -0.83 -15.84 -0.65 8.89e-43 Height; LIHC cis rs6430585 0.583 rs12472293 chr2:136648077 T/C cg07169764 chr2:136633963 MCM6 1.35 23.43 0.78 4.43e-73 Corneal structure; LIHC cis rs7098414 0.511 rs10788603 chr10:82148137 G/T cg01528321 chr10:82214614 TSPAN14 0.45 6.83 0.35 3.89e-11 Post bronchodilator FEV1; LIHC cis rs60871478 0.947 rs62432239 chr7:794576 C/T cg04727924 chr7:799746 HEATR2 -0.58 -8.64 -0.42 2.11e-16 Cerebrospinal P-tau181p levels; LIHC cis rs9733 0.596 rs72702504 chr1:150635374 G/C cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs17152411 0.625 rs12265337 chr10:126618620 G/A cg07906193 chr10:126599966 NA -0.3 -5.86 -0.3 1.06e-8 Height; LIHC trans rs3812049 0.826 rs34576922 chr5:127364103 C/G cg16011800 chr17:1958478 HIC1 0.51 7.35 0.37 1.5e-12 Lymphocyte counts;Red cell distribution width; LIHC cis rs12701220 0.655 rs7799656 chr7:1140515 C/T cg26769984 chr7:1090371 C7orf50 0.46 5.82 0.3 1.34e-8 Bronchopulmonary dysplasia; LIHC cis rs1670533 1.000 rs10007978 chr4:1060984 A/T cg27284194 chr4:1044797 NA 0.59 8.71 0.43 1.37e-16 Recombination rate (females); LIHC cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg12310025 chr6:25882481 NA 0.53 6.91 0.35 2.45e-11 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.41 0.45 7.44e-19 Bipolar disorder; LIHC cis rs4474465 0.850 rs10793322 chr11:78242615 T/C cg27205649 chr11:78285834 NARS2 0.39 5.98 0.31 5.63e-9 Alzheimer's disease (survival time); LIHC cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs2250402 0.510 rs2291621 chr15:40324837 C/T cg20255370 chr15:40268687 EIF2AK4 -0.51 -5.8 -0.3 1.48e-8 Corneal curvature; LIHC cis rs28374715 0.783 rs11635269 chr15:41570710 A/G cg18705301 chr15:41695430 NDUFAF1 -1.14 -15.18 -0.63 3.67e-40 Ulcerative colitis; LIHC cis rs244293 0.864 rs244374 chr17:53183754 A/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.52 0.38 4.85e-13 Menarche (age at onset); LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg06873352 chr17:61820015 STRADA 0.57 8.7 0.43 1.44e-16 Height; LIHC cis rs7772486 0.790 rs9497427 chr6:146238302 T/A cg23711669 chr6:146136114 FBXO30 -0.62 -10.87 -0.51 7.96e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs77633900 0.614 rs280013 chr15:76978139 C/T cg21673338 chr15:77095150 SCAPER 0.51 7.6 0.38 2.89e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs929354 0.605 rs7806314 chr7:156946903 A/T cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs5769765 0.773 rs7410304 chr22:50316835 T/C cg09182678 chr22:50328711 NA -0.39 -5.79 -0.3 1.61e-8 Schizophrenia; LIHC cis rs10870270 1.000 rs7898755 chr10:133777122 G/A cg26149184 chr10:133730230 NA 0.47 7.51 0.38 5.31e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1403694 0.695 rs3806689 chr3:186435077 A/G cg12454167 chr3:186435060 KNG1 0.38 8.97 0.44 2.01e-17 Blood protein levels; LIHC cis rs367615 0.679 rs10070786 chr5:108815081 T/G cg17395555 chr5:108820864 NA 0.39 8.65 0.42 2.08e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs7296418 0.961 rs1790121 chr12:123604492 G/A cg00376283 chr12:123451042 ABCB9 0.74 13.01 0.58 1.05e-31 Platelet count; LIHC cis rs2839186 1.000 rs2839186 chr21:47690068 C/T cg12379764 chr21:47803548 PCNT -0.57 -8.18 -0.4 5.78e-15 Testicular germ cell tumor; LIHC cis rs9818758 0.607 rs80170003 chr3:48951640 T/C cg00383909 chr3:49044727 WDR6 1.1 7.87 0.39 4.78e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg13409248 chr3:40428643 ENTPD3 -0.51 -8.63 -0.42 2.29e-16 Renal cell carcinoma; LIHC cis rs35110281 0.548 rs2838350 chr21:45109972 T/C cg04455712 chr21:45112962 RRP1B 0.54 9.09 0.44 8.33e-18 Mean corpuscular volume; LIHC cis rs7615952 0.641 rs4490307 chr3:125712676 T/G cg05084668 chr3:125655381 ALG1L -0.45 -7.5 -0.38 5.49e-13 Blood pressure (smoking interaction); LIHC cis rs1580019 0.665 rs34147895 chr7:32531796 G/C cg06627557 chr7:32535165 LSM5;AVL9 1.1 23.48 0.79 2.81e-73 Cognitive ability; LIHC cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg18252515 chr7:66147081 NA -1.3 -17.27 -0.68 1.73e-48 Diabetic kidney disease; LIHC cis rs11626933 1.000 rs61986782 chr14:90751344 C/T cg14092571 chr14:90743983 NA -0.9 -14.86 -0.63 6.84e-39 Gut microbiota (bacterial taxa); LIHC trans rs6011368 0.840 rs6062361 chr20:62904542 C/T cg13869341 chr1:15865 WASH5P -0.38 -6.67 -0.34 1.01e-10 Clozapine-induced cytotoxicity; LIHC cis rs12291225 0.679 rs10832240 chr11:14304744 C/T cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.1e-31 Sense of smell; LIHC cis rs6570726 0.577 rs867056 chr6:145784805 A/C cg05347473 chr6:146136440 FBXO30 -0.49 -7.06 -0.36 9.21e-12 Lobe attachment (rater-scored or self-reported); LIHC trans rs10411161 0.721 rs10401778 chr19:52384315 C/T cg22319618 chr22:45562946 NUP50 -0.6 -8.17 -0.4 6.12e-15 Breast cancer; LIHC cis rs7940866 0.801 rs10894296 chr11:130840433 T/G cg12179176 chr11:130786555 SNX19 0.63 9.1 0.44 7.59e-18 Schizophrenia; LIHC cis rs12368653 1.000 rs12371356 chr12:58135420 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.7 -0.34 8.45e-11 Multiple sclerosis; LIHC cis rs919433 0.588 rs11690163 chr2:198527507 A/T cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg03806693 chr22:41940476 POLR3H -1.14 -13.49 -0.59 1.54e-33 Vitiligo; LIHC cis rs10791323 0.628 rs2853117 chr11:133705266 T/G cg06766960 chr11:133703094 NA -0.66 -10.98 -0.51 3.27e-24 Childhood ear infection; LIHC cis rs7309 0.935 rs6432674 chr2:162025322 G/T cg08807892 chr2:162101083 NA 0.45 7.64 0.38 2.25e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs7503807 1.000 rs8079537 chr17:78600818 A/G cg09596252 chr17:78655493 RPTOR 0.39 7.07 0.36 8.85e-12 Obesity; LIHC cis rs1401999 1.000 rs6443927 chr3:183718864 A/G cg01324343 chr3:183735012 ABCC5 0.77 13.12 0.58 3.93e-32 Anterior chamber depth; LIHC cis rs6582630 0.555 rs11182429 chr12:38526679 A/C cg13010199 chr12:38710504 ALG10B 0.42 5.78 0.3 1.67e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs2845885 0.793 rs35927325 chr11:63882495 C/T cg05555928 chr11:63887634 MACROD1 -0.51 -6.38 -0.33 5.61e-10 Body mass index; LIHC cis rs1008375 1.000 rs10805357 chr4:17652352 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.9 0.3 8.54e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs909002 0.811 rs11575883 chr1:32085485 G/A cg13919466 chr1:32135498 COL16A1 -0.33 -6.28 -0.32 1.02e-9 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs1558377 chr4:17650758 A/G cg02297831 chr4:17616191 MED28 0.5 7.8 0.39 7.38e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3008870 0.816 rs1118392 chr1:67366549 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.82 -14.36 -0.61 6.23e-37 Lymphocyte percentage of white cells; LIHC cis rs9640161 0.750 rs59211922 chr7:150023790 T/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.89 -0.43 3.45e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs3823572 0.542 rs2971974 chr7:133644598 C/T cg03336402 chr7:133662267 EXOC4 0.49 6.18 0.32 1.79e-9 Intelligence (multi-trait analysis); LIHC cis rs11583043 0.874 rs6577219 chr1:101415707 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 9.45 0.46 5.4e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1506636 1.000 rs2429617 chr7:123418027 A/G cg03229431 chr7:123269106 ASB15 0.6 11.85 0.54 2.27e-27 Plateletcrit;Platelet count; LIHC cis rs7089973 0.604 rs3758603 chr10:116605368 T/C cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs244293 0.965 rs244363 chr17:53188893 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.47 -0.37 6.93e-13 Menarche (age at onset); LIHC cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg02290350 chr8:58132656 NA 0.37 7.63 0.38 2.32e-13 Developmental language disorder (linguistic errors); LIHC cis rs10792665 0.512 rs2127363 chr11:82641001 C/A cg24227371 chr11:82718527 RAB30 -0.28 -6.59 -0.34 1.67e-10 Obesity-related traits; LIHC cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg17971929 chr21:40555470 PSMG1 -0.43 -6.45 -0.33 3.89e-10 Cognitive function; LIHC cis rs79387448 0.745 rs7583683 chr2:103113763 C/T cg09003973 chr2:102972529 NA -0.91 -7.31 -0.37 1.94e-12 Gut microbiota (bacterial taxa); LIHC cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg02290350 chr8:58132656 NA -0.43 -8.75 -0.43 9.56e-17 Developmental language disorder (linguistic errors); LIHC cis rs1775715 0.737 rs2808072 chr10:32205504 A/T cg14930904 chr10:32216787 ARHGAP12 0.36 6.29 0.32 9.94e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs2281845 0.929 rs7549337 chr1:201097609 T/G cg24849736 chr1:201084428 NA -0.31 -6.1 -0.31 2.93e-9 Permanent tooth development; LIHC cis rs6840360 0.550 rs6836343 chr4:152497564 A/G cg22705602 chr4:152727874 NA -0.33 -6.49 -0.33 2.93e-10 Intelligence (multi-trait analysis); LIHC cis rs9583531 0.600 rs7986286 chr13:111357207 A/G cg15841412 chr13:111365552 ING1 0.47 5.93 0.31 7.54e-9 Coronary artery disease; LIHC cis rs9611565 0.592 rs8779 chr22:42070276 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.61 0.5 6.31e-23 Vitiligo; LIHC cis rs7572733 0.534 rs700685 chr2:198715972 A/G cg03934865 chr2:198174659 NA 0.46 6.67 0.34 1.03e-10 Dermatomyositis; LIHC cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.13 -0.31 2.46e-9 Aortic root size; LIHC cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg18305652 chr10:134549665 INPP5A 0.48 7.62 0.38 2.5e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg26570765 chr4:1273065 NA 0.3 5.95 0.31 6.67e-9 Obesity-related traits; LIHC cis rs875971 0.867 rs1002053 chr7:65798545 G/A cg11764359 chr7:65958608 NA -0.9 -16.66 -0.67 4.73e-46 Aortic root size; LIHC cis rs903552 1.000 rs12908310 chr15:102003635 A/G cg25677261 chr15:102009856 PCSK6 -0.43 -5.92 -0.3 7.76e-9 Diabetic kidney disease; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.41 0.33 4.8e-10 Total body bone mineral density; LIHC cis rs7829975 0.606 rs6422352 chr8:8794193 A/G cg06636001 chr8:8085503 FLJ10661 -0.41 -6.49 -0.33 2.99e-10 Mood instability; LIHC cis rs1401999 0.668 rs6806313 chr3:183642152 G/C cg01324343 chr3:183735012 ABCC5 0.54 8.68 0.43 1.61e-16 Anterior chamber depth; LIHC cis rs950169 0.959 rs66801143 chr15:84736657 C/T cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs2404602 0.647 rs11072625 chr15:77084984 A/G cg23625390 chr15:77176239 SCAPER 0.53 8.68 0.42 1.67e-16 Blood metabolite levels; LIHC cis rs473651 0.935 rs483166 chr2:239346641 C/T cg18131467 chr2:239335373 ASB1 -1.07 -20.41 -0.74 4.11e-61 Multiple system atrophy; LIHC cis rs79387448 0.745 rs17027413 chr2:103153667 A/G cg09003973 chr2:102972529 NA -0.97 -8.49 -0.42 6.33e-16 Gut microbiota (bacterial taxa); LIHC cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg00149659 chr3:10157352 C3orf10 0.68 6.93 0.35 2.11e-11 Alzheimer's disease; LIHC cis rs74181299 0.717 rs11893423 chr2:65350949 G/A cg05010058 chr2:65284262 CEP68 -0.42 -6.91 -0.35 2.4e-11 Pulse pressure; LIHC cis rs6547741 1.000 rs2384654 chr2:27847364 C/T cg27432699 chr2:27873401 GPN1 0.78 12.7 0.57 1.55e-30 Oral cavity cancer; LIHC cis rs9399137 0.529 rs7739722 chr6:135282225 T/C cg24558204 chr6:135376177 HBS1L 0.56 9.44 0.45 5.83e-19 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC trans rs916888 0.821 rs70600 chr17:44860021 C/T cg16836995 chr17:43662488 NA -0.75 -7.61 -0.38 2.7e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1005277 0.505 rs7069702 chr10:38247359 G/T cg00409905 chr10:38381863 ZNF37A 0.56 9.74 0.47 6.01e-20 Extrinsic epigenetic age acceleration; LIHC cis rs921968 0.608 rs7598056 chr2:219352511 A/C cg18887096 chr2:219472410 PLCD4 0.36 6.39 0.33 5.46e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2153535 0.601 rs2327054 chr6:8443130 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.77 0.54 4.25e-27 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01586524 chr8:67341819 RRS1 0.47 6.99 0.35 1.43e-11 Pancreatic cancer; LIHC cis rs769267 0.895 rs2916069 chr19:19520358 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.8 0.3 1.5e-8 Tonsillectomy; LIHC cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg05368731 chr17:41323189 NBR1 0.73 12.12 0.55 2.36e-28 Menopause (age at onset); LIHC cis rs1003719 0.628 rs2252402 chr21:38520720 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.52 6.64 0.34 1.27e-10 Eye color traits; LIHC cis rs6586163 0.872 rs1926200 chr10:90746533 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.53 -7.76 -0.39 1.02e-13 Chronic lymphocytic leukemia; LIHC cis rs10870270 1.000 rs4880263 chr10:133787629 C/T cg26149184 chr10:133730230 NA 0.49 7.78 0.39 8.54e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs597539 0.652 rs546382 chr11:68704264 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.25 0.48 1.14e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs870825 0.616 rs4437299 chr4:185643223 T/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs17125944 0.773 rs1952089 chr14:53339777 C/T cg00686598 chr14:53173677 PSMC6 -0.8 -8.77 -0.43 8.43e-17 Alzheimer's disease (late onset); LIHC cis rs796364 0.715 rs11688872 chr2:201052418 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.63 -6.73 -0.34 7.05e-11 Schizophrenia; LIHC cis rs4665809 1.000 rs4233708 chr2:26291345 C/T cg04944784 chr2:26401820 FAM59B -0.69 -8.69 -0.43 1.55e-16 Gut microbiome composition (summer); LIHC cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg00750074 chr16:89608354 SPG7 -0.54 -8.72 -0.43 1.22e-16 Multiple myeloma (IgH translocation); LIHC cis rs5758343 1 rs5758343 chr22:41816652 A/T cg03806693 chr22:41940476 POLR3H 1.12 12.8 0.57 6.57e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs75920871 0.588 rs721783 chr11:116907449 C/T cg01368799 chr11:117014884 PAFAH1B2 -0.44 -5.81 -0.3 1.44e-8 Subjective well-being; LIHC cis rs1997103 1.000 rs6958022 chr7:55397389 G/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9549367 0.713 rs11620600 chr13:113829090 G/A cg18105134 chr13:113819100 PROZ -0.76 -13.02 -0.58 9.81e-32 Platelet distribution width; LIHC cis rs6001982 0.541 rs17002067 chr22:41050306 C/G cg14879645 chr22:41048474 NA 0.4 5.91 0.3 8.13e-9 Breast cancer; LIHC cis rs6500602 0.893 rs934888 chr16:4462832 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 5.94 0.31 6.92e-9 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03172837 chr2:236949449 AGAP1 0.41 6.34 0.32 7.11e-10 Pancreatic cancer; LIHC cis rs2070433 0.539 rs1008548 chr21:47959692 G/A cg12379764 chr21:47803548 PCNT 0.64 9.64 0.46 1.34e-19 Lymphocyte counts; LIHC cis rs6748734 0.948 rs4471886 chr2:241838622 T/C cg08694578 chr2:241835147 C2orf54 -0.63 -10.16 -0.48 2.3e-21 Urinary metabolites; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16451004 chr11:27494421 LGR4 0.45 6.35 0.32 7.02e-10 Lung function (FEV1/FVC); LIHC cis rs7677751 0.806 rs7681399 chr4:55090886 T/G cg17187183 chr4:55093834 PDGFRA 0.66 8.37 0.41 1.54e-15 Corneal astigmatism; LIHC cis rs12478296 0.901 rs67423532 chr2:243004719 A/G cg18898632 chr2:242989856 NA -0.47 -6.5 -0.33 2.86e-10 Obesity-related traits; LIHC cis rs2976388 1.000 rs1045574 chr8:143763958 C/T cg06565975 chr8:143823917 SLURP1 -0.33 -6.29 -0.32 9.6e-10 Urinary tract infection frequency; LIHC cis rs3741404 0.574 rs638227 chr11:63871549 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 10.94 0.51 4.5e-24 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14195458 chr4:89381447 HERC5 0.27 6.49 0.33 3e-10 Cognitive function; LIHC cis rs1733410 0.504 rs11181874 chr12:37912890 C/A cg26384229 chr12:38710491 ALG10B -0.47 -6.64 -0.34 1.23e-10 Morning vs. evening chronotype; LIHC cis rs875971 0.545 rs7783889 chr7:65748353 T/A cg11764359 chr7:65958608 NA 0.58 8.18 0.4 5.67e-15 Aortic root size; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs9911578 0.967 rs9907940 chr17:56663842 A/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.63 -0.42 2.41e-16 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.904 rs8078638 chr17:28290358 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 13.3 0.58 8.25e-33 Coffee consumption (cups per day); LIHC cis rs963731 0.649 rs297150 chr2:39326164 C/T cg04010122 chr2:39346883 SOS1 -0.67 -6.07 -0.31 3.31e-9 Corticobasal degeneration; LIHC trans rs1728785 1.000 rs3203684 chr16:68600440 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.51 -6.19 -0.32 1.68e-9 Ulcerative colitis; LIHC cis rs34779708 1.000 rs34779708 chr10:35466185 T/G cg03585969 chr10:35415529 CREM 0.8 11.86 0.54 2e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1008375 1.000 rs4698198 chr4:17656536 G/A cg02297831 chr4:17616191 MED28 0.5 7.81 0.39 6.97e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9811920 0.609 rs793466 chr3:99609837 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs1023500 0.596 rs5758562 chr22:42448238 C/G cg05082376 chr22:42548792 NA -0.4 -5.89 -0.3 9.43e-9 Schizophrenia; LIHC cis rs35306767 0.953 rs35174953 chr10:961191 C/A cg26597838 chr10:835615 NA 0.98 11.98 0.54 7.58e-28 Eosinophil percentage of granulocytes; LIHC cis rs10197940 0.510 rs7557092 chr2:152423459 T/A cg19508488 chr2:152266495 RIF1 0.5 6.83 0.35 3.97e-11 Lung cancer; LIHC cis rs1577917 0.917 rs1414201 chr6:86500316 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.86 -0.39 4.91e-14 Response to antipsychotic treatment; LIHC cis rs10883723 0.847 rs3808934 chr10:104264280 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6964587 0.900 rs7783674 chr7:91784212 T/A cg17063962 chr7:91808500 NA 1.06 22.64 0.77 5.25e-70 Breast cancer; LIHC cis rs7107174 0.681 rs3102742 chr11:77949334 G/T cg02023728 chr11:77925099 USP35 0.51 9.4 0.45 8.16e-19 Testicular germ cell tumor; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01052087 chr20:10414899 C20orf94;MKKS 0.42 6.32 0.32 8.37e-10 Calcium levels; LIHC cis rs1552244 0.608 rs6764807 chr3:9998803 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.81 0.39 6.86e-14 Alzheimer's disease; LIHC cis rs6545883 0.929 rs10193666 chr2:61629408 C/T cg15711740 chr2:61764176 XPO1 0.43 6.0 0.31 5e-9 Tuberculosis; LIHC cis rs3812831 0.629 rs7318527 chr13:114946956 C/T cg08824895 chr13:115047677 UPF3A 0.48 6.89 0.35 2.73e-11 Schizophrenia; LIHC cis rs10751667 0.557 rs4077531 chr11:1013167 G/A cg10932868 chr11:921992 NA 0.32 5.88 0.3 9.97e-9 Alzheimer's disease (late onset); LIHC cis rs1865721 1.000 rs62089509 chr18:73194519 G/A cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.17e-13 Intelligence; LIHC cis rs3736594 1.000 rs13013484 chr2:27988821 G/A cg27432699 chr2:27873401 GPN1 -0.4 -6.34 -0.32 7.21e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs7647973 1.000 rs11720542 chr3:49357427 A/G cg07636037 chr3:49044803 WDR6 0.51 6.23 0.32 1.38e-9 Menarche (age at onset); LIHC cis rs4555082 1.000 rs7146683 chr14:105759385 A/G cg06808227 chr14:105710500 BRF1 -0.55 -7.57 -0.38 3.5e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs4319547 0.656 rs6488951 chr12:122873928 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.28 -0.37 2.3e-12 Body mass index; LIHC trans rs2579103 0.767 rs2579096 chr12:90662255 C/G cg00091569 chr3:40428383 ENTPD3 0.37 6.08 0.31 3.19e-9 Body mass index; LIHC cis rs9733 0.628 rs11807409 chr1:150683423 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.13e-9 Tonsillectomy; LIHC trans rs9951602 0.512 rs9949512 chr18:76641845 T/C cg02800362 chr5:177631904 HNRNPAB 0.64 10.24 0.48 1.24e-21 Obesity-related traits; LIHC cis rs2115630 0.755 rs7169629 chr15:85191274 C/G cg12501888 chr15:85177176 SCAND2 0.49 7.64 0.38 2.2e-13 P wave terminal force; LIHC trans rs2096176 0.581 rs7895318 chr10:26423091 A/G cg01396774 chr2:218299024 DIRC3 -0.31 -6.09 -0.31 3.04e-9 Obesity-related traits; LIHC cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg18654377 chr3:49208889 KLHDC8B -0.5 -5.99 -0.31 5.19e-9 Menarche (age at onset); LIHC cis rs13217239 0.646 rs10946897 chr6:26995251 A/C cg18867708 chr6:26865862 GUSBL1 0.52 8.07 0.4 1.19e-14 Schizophrenia; LIHC cis rs6429082 0.818 rs291340 chr1:235674379 C/T cg26050004 chr1:235667680 B3GALNT2 0.48 7.4 0.37 1.05e-12 Adiposity; LIHC cis rs2625529 0.824 rs12901886 chr15:72408069 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.86 -0.3 1.06e-8 Red blood cell count; LIHC cis rs10870270 0.956 rs7915388 chr10:133734972 G/A cg17892150 chr10:133769511 PPP2R2D -0.69 -13.16 -0.58 2.7e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7312933 1.000 rs12372623 chr12:42531666 G/A cg17420585 chr12:42539391 GXYLT1 -0.37 -5.94 -0.31 6.95e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6502050 0.835 rs7209474 chr17:80136418 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -6.0 -0.31 5.01e-9 Life satisfaction; LIHC cis rs4845459 0.933 rs11205044 chr1:152593437 T/C cg20634798 chr1:152595351 LCE3A -0.31 -6.02 -0.31 4.48e-9 Psoriasis; LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs67478160 0.608 rs11160760 chr14:104248938 G/T cg08213375 chr14:104286397 PPP1R13B 0.66 12.8 0.57 6.45e-31 Schizophrenia; LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg02951883 chr7:2050386 MAD1L1 0.7 11.58 0.53 2.27e-26 Bipolar disorder and schizophrenia; LIHC cis rs734999 0.545 rs10910105 chr1:2538209 G/A cg18854424 chr1:2615690 NA 0.33 7.08 0.36 8e-12 Ulcerative colitis; LIHC cis rs2073300 0.609 rs2295238 chr20:23387946 C/G cg16736954 chr20:23401023 NAPB 0.71 8.48 0.42 6.86e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs929354 0.772 rs1182448 chr7:157021415 G/A cg16102536 chr7:156981717 UBE3C -0.35 -5.9 -0.3 8.56e-9 Body mass index; LIHC cis rs58688157 0.924 rs35865896 chr11:584591 A/G cg16486109 chr11:613632 IRF7 0.6 6.48 0.33 3.28e-10 Systemic lupus erythematosus; LIHC cis rs2236918 0.710 rs1776159 chr1:242018583 C/G cg17736920 chr1:242011382 EXO1 0.44 6.53 0.33 2.41e-10 Menopause (age at onset); LIHC cis rs763121 0.853 rs5757213 chr22:39053888 C/T cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs11971779 0.680 rs10229358 chr7:139052545 C/T cg07862535 chr7:139043722 LUC7L2 -0.59 -10.2 -0.48 1.73e-21 Diisocyanate-induced asthma; LIHC cis rs11212737 0.765 rs2640764 chr11:108511063 G/A cg22776369 chr11:108536276 DDX10 0.35 5.88 0.3 9.82e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04784546 chr15:50646617 GABPB1;FLJ10038;LOC100129387 -0.5 -6.29 -0.32 9.85e-10 Systolic blood pressure; LIHC cis rs2842992 0.915 rs1967802 chr6:160097791 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.53 8.91 0.43 3e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs7927771 0.507 rs3740699 chr11:47504075 G/T cg20307385 chr11:47447363 PSMC3 0.74 10.55 0.5 1.04e-22 Subjective well-being; LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.51 -7.33 -0.37 1.73e-12 Lymphocyte counts; LIHC cis rs1018836 0.851 rs7014073 chr8:91618548 T/C cg16814680 chr8:91681699 NA -0.61 -9.76 -0.47 5.08e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2290416 0.892 rs62522168 chr8:144679776 G/A cg26536354 chr8:144654954 C8orf73 0.55 6.19 0.32 1.72e-9 Attention deficit hyperactivity disorder; LIHC cis rs7917772 0.503 rs7902306 chr10:104290462 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.78 11.23 0.52 4.18e-25 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1401999 1.000 rs6802849 chr3:183698943 A/C cg01324343 chr3:183735012 ABCC5 0.76 12.9 0.57 2.74e-31 Anterior chamber depth; LIHC cis rs6121246 0.909 rs6089070 chr20:30377773 A/G cg13852791 chr20:30311386 BCL2L1 -0.89 -8.61 -0.42 2.8e-16 Mean corpuscular hemoglobin; LIHC trans rs13381277 1.000 rs9956431 chr18:74329251 G/T cg17352830 chr21:37617589 DOPEY2 -0.55 -6.4 -0.33 5e-10 Dental caries; LIHC cis rs12594515 0.694 rs2068294 chr15:45985548 G/T cg19682013 chr15:45996608 NA 0.4 6.85 0.35 3.34e-11 Waist circumference;Weight; LIHC cis rs769267 0.930 rs747050 chr19:19584987 C/G cg03709012 chr19:19516395 GATAD2A 1.02 18.35 0.7 7.4e-53 Tonsillectomy; LIHC cis rs735396 0.770 rs2264782 chr12:121432603 C/T cg25281562 chr12:121454272 C12orf43 0.34 5.98 0.31 5.66e-9 N-glycan levels; LIHC cis rs11098499 0.588 rs2389874 chr4:120554991 A/G cg09307838 chr4:120376055 NA -0.57 -8.74 -0.43 1.07e-16 Corneal astigmatism; LIHC cis rs907683 0.584 rs2854903 chr2:220288979 C/T cg15015639 chr2:220282977 DES -0.37 -8.71 -0.43 1.3e-16 Resting heart rate; LIHC cis rs933688 0.941 rs2887007 chr5:90740531 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.8 0.69 1.24e-50 Smoking behavior; LIHC cis rs7647973 0.626 rs1352889 chr3:49652148 T/C cg03060546 chr3:49711283 APEH 0.59 6.78 0.34 5.41e-11 Menarche (age at onset); LIHC cis rs60871478 0.545 rs35400476 chr7:795686 A/G cg13798912 chr7:905769 UNC84A 0.44 5.81 0.3 1.45e-8 Cerebrospinal P-tau181p levels; LIHC cis rs6456156 0.583 rs7748224 chr6:167456860 C/T cg07741184 chr6:167504864 NA 0.28 6.55 0.33 2.1e-10 Primary biliary cholangitis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00734800 chr3:50388182 TUSC4;CYB561D2 0.45 7.14 0.36 5.75e-12 Pancreatic cancer; LIHC cis rs738321 0.757 rs2284062 chr22:38544221 A/G cg25457927 chr22:38595422 NA -0.34 -7.69 -0.38 1.59e-13 Breast cancer; LIHC cis rs10454142 0.700 rs17037289 chr2:48587198 A/G cg15846641 chr2:48541264 FOXN2 0.5 6.09 0.31 3.12e-9 Sex hormone-binding globulin levels; LIHC cis rs6430585 0.591 rs3098103 chr2:136656094 T/C cg07169764 chr2:136633963 MCM6 1.29 21.47 0.76 2.32e-65 Corneal structure; LIHC cis rs3741151 1.000 rs74776668 chr11:73065909 G/A cg17517138 chr11:73019481 ARHGEF17 0.93 6.79 0.34 4.98e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs78545713 0.649 rs11751062 chr6:26216165 C/T cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC trans rs12478296 0.685 rs12473450 chr2:242991746 C/T cg01596870 chr19:55963115 NA -0.64 -9.37 -0.45 1.03e-18 Obesity-related traits; LIHC cis rs2549003 0.934 rs2549006 chr5:131827065 A/G cg21138405 chr5:131827807 IRF1 -0.38 -9.69 -0.46 8.99e-20 Asthma (sex interaction); LIHC cis rs4631830 0.657 rs2611502 chr10:51500301 A/G cg20129853 chr10:51489980 NA -0.4 -8.72 -0.43 1.21e-16 Prostate-specific antigen levels; LIHC trans rs9951602 0.512 rs4799245 chr18:76653397 T/C cg02800362 chr5:177631904 HNRNPAB 0.66 10.52 0.49 1.33e-22 Obesity-related traits; LIHC cis rs1008375 1.000 rs56308330 chr4:17643050 G/A cg02297831 chr4:17616191 MED28 0.49 7.61 0.38 2.77e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs40363 0.523 rs757270 chr16:3534451 C/T cg21433313 chr16:3507492 NAT15 -0.39 -6.4 -0.33 4.99e-10 Tuberculosis; LIHC cis rs2274273 0.870 rs946059 chr14:55847466 A/G cg04306507 chr14:55594613 LGALS3 0.32 5.96 0.31 6.31e-9 Protein biomarker; LIHC cis rs9291683 0.632 rs11734375 chr4:10046298 A/G cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.6e-13 Bone mineral density; LIHC cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg06238570 chr21:40685208 BRWD1 -0.53 -8.69 -0.43 1.56e-16 Cognitive function; LIHC cis rs5769765 0.954 rs5769762 chr22:50264042 G/A cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs9814567 0.752 rs4306899 chr3:134334513 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.59 9.47 0.46 4.71e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3741404 0.791 rs11603192 chr11:63927695 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.95 16.13 0.66 6.44e-44 Platelet count; LIHC cis rs12477438 0.501 rs11123770 chr2:99825102 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 13.84 0.6 6.87e-35 Chronic sinus infection; LIHC cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg25894440 chr7:65020034 NA -0.55 -6.33 -0.32 7.79e-10 Diabetic kidney disease; LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg14828511 chr1:107599125 PRMT6 -0.46 -6.58 -0.34 1.79e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7107174 1.000 rs10899452 chr11:77995143 A/C cg02023728 chr11:77925099 USP35 0.53 10.01 0.48 7.45e-21 Testicular germ cell tumor; LIHC trans rs916888 0.821 rs199509 chr17:44858728 G/A cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2976388 0.609 rs2585144 chr8:143800269 A/T cg06565975 chr8:143823917 SLURP1 0.34 6.66 0.34 1.1e-10 Urinary tract infection frequency; LIHC cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg11890956 chr21:40555474 PSMG1 -0.87 -11.73 -0.54 5.98e-27 Cognitive function; LIHC cis rs2072499 0.932 rs2540183 chr1:156164885 C/G cg25208724 chr1:156163844 SLC25A44 0.88 14.17 0.61 3.41e-36 Testicular germ cell tumor; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg05309934 chr10:5855475 GDI2 -0.53 -6.2 -0.32 1.62e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg27121462 chr16:89883253 FANCA 0.42 6.63 0.34 1.3e-10 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23104823 chr14:45553408 PRPF39 0.44 6.54 0.33 2.29e-10 Pancreatic cancer; LIHC cis rs713477 0.817 rs55868790 chr14:55913275 T/C cg13175173 chr14:55914753 NA -0.35 -8.1 -0.4 9.62e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs6430585 0.528 rs586964 chr2:136652491 G/A cg07169764 chr2:136633963 MCM6 1.32 21.74 0.76 2.04e-66 Corneal structure; LIHC cis rs11951515 0.508 rs11958046 chr5:43583389 T/C cg01983248 chr5:43482804 C5orf28 -0.37 -6.1 -0.31 2.9e-9 Metabolite levels (X-11787); LIHC cis rs35110281 0.517 rs11089020 chr21:44939991 C/T cg21573476 chr21:45109991 RRP1B -0.48 -8.7 -0.43 1.45e-16 Mean corpuscular volume; LIHC trans rs7246657 0.943 rs2045908 chr19:37979768 C/G cg10208301 chr11:6592745 DNHD1 0.45 6.45 0.33 3.73e-10 Coronary artery calcification; LIHC cis rs826838 0.900 rs9739128 chr12:38948960 A/T cg13010199 chr12:38710504 ALG10B 0.6 7.48 0.38 6.18e-13 Heart rate; LIHC trans rs7674212 0.541 rs2623070 chr4:104037388 A/G cg16471864 chr4:38666270 KLF3;FLJ13197 0.42 6.05 0.31 3.75e-9 Type 2 diabetes; LIHC cis rs9916302 0.904 rs12450559 chr17:37694709 G/A cg03013999 chr17:37608204 MED1 0.35 5.78 0.3 1.71e-8 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.913 rs55883802 chr11:68278829 G/A cg16797656 chr11:68205561 LRP5 0.52 8.25 0.41 3.4e-15 Total body bone mineral density; LIHC cis rs6582630 0.519 rs4405392 chr12:38293661 A/C cg26384229 chr12:38710491 ALG10B 0.59 8.13 0.4 7.95e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs8114671 0.562 rs2378292 chr20:33485178 T/C cg07148914 chr20:33460835 GGT7 0.66 10.12 0.48 3.15e-21 Height; LIHC cis rs1997103 1.000 rs9649851 chr7:55398692 C/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1165668 0.785 rs1165681 chr12:104325111 A/G cg21863207 chr12:104234989 NT5DC3 -0.41 -6.87 -0.35 3.03e-11 Coronary heart disease (SNP X SNP interaction); LIHC cis rs8013055 0.846 rs8013827 chr14:105970176 C/T cg19700328 chr14:106028568 NA 0.32 7.07 0.36 8.81e-12 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs722599 0.683 rs17102847 chr14:75324780 A/G cg11812906 chr14:75593930 NEK9 -0.4 -6.18 -0.32 1.85e-9 IgG glycosylation; LIHC cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.88 7.96 0.4 2.52e-14 Platelet count; LIHC cis rs13064411 0.696 rs6768979 chr3:113204149 G/A cg18753928 chr3:113234510 CCDC52 -0.44 -6.25 -0.32 1.21e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs7582180 0.585 rs6736311 chr2:100950599 C/G cg14675211 chr2:100938903 LONRF2 0.53 8.58 0.42 3.45e-16 Intelligence (multi-trait analysis); LIHC cis rs6546550 0.901 rs3732266 chr2:70057448 T/G cg02498382 chr2:70120550 SNRNP27 -0.4 -6.49 -0.33 2.94e-10 Prevalent atrial fibrillation; LIHC cis rs7903847 0.642 rs10882923 chr10:99159018 G/A cg08345082 chr10:99160200 RRP12 -0.39 -6.72 -0.34 7.76e-11 Granulocyte percentage of myeloid white cells; LIHC trans rs637571 0.524 rs674363 chr11:65699134 G/A cg17712092 chr4:129076599 LARP1B -0.71 -10.38 -0.49 4.11e-22 Eosinophil percentage of white cells; LIHC cis rs7903847 0.612 rs72838764 chr10:99142107 T/C cg06359132 chr10:99160096 RRP12 -0.41 -6.05 -0.31 3.71e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs66569888 0.789 rs1317569 chr2:106735490 C/A cg15412446 chr2:106886593 NA -0.69 -6.87 -0.35 3.07e-11 Facial morphology (factor 23); LIHC cis rs2737618 0.651 rs2249156 chr1:200083541 A/G cg21825944 chr1:200113062 NR5A2 0.49 8.14 0.4 7.41e-15 Uric acid levels; LIHC cis rs9457247 1.000 rs2757042 chr6:167371234 A/T cg23791538 chr6:167370224 RNASET2 0.61 9.47 0.46 4.92e-19 Crohn's disease; LIHC cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg18252515 chr7:66147081 NA -1.24 -15.92 -0.65 4.31e-43 Diabetic kidney disease; LIHC cis rs9467773 1.000 rs6456734 chr6:26566965 G/T cg09904177 chr6:26538194 HMGN4 0.66 13.75 0.6 1.5e-34 Intelligence (multi-trait analysis); LIHC cis rs12220238 1.000 rs10824112 chr10:75969003 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.55 0.33 2.15e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10492096 0.947 rs11559082 chr12:6602367 C/T cg13857086 chr12:6580257 VAMP1 0.58 6.14 0.31 2.32e-9 Hip geometry; LIHC cis rs11628318 0.515 rs7152144 chr14:103126101 C/T cg01864069 chr14:103024347 NA 0.36 5.99 0.31 5.22e-9 Platelet count; LIHC cis rs7903847 0.596 rs10882934 chr10:99170995 T/G cg06359132 chr10:99160096 RRP12 -0.38 -5.97 -0.31 6.01e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs921968 0.643 rs2556385 chr2:219532905 G/A cg18887096 chr2:219472410 PLCD4 -0.39 -6.69 -0.34 9.17e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg02931644 chr1:25747376 RHCE 0.35 7.73 0.39 1.2e-13 Erythrocyte sedimentation rate; LIHC cis rs875971 0.862 rs11773628 chr7:65982631 G/T cg18252515 chr7:66147081 NA 0.43 6.24 0.32 1.27e-9 Aortic root size; LIHC cis rs10504229 0.817 rs55891651 chr8:58167600 C/T cg21724239 chr8:58056113 NA 0.42 5.71 0.3 2.39e-8 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.692 rs10444858 chr15:76962504 T/C cg23625390 chr15:77176239 SCAPER 0.35 5.76 0.3 1.91e-8 Blood metabolite levels; LIHC trans rs4799915 1.000 rs4799915 chr18:34928639 A/G cg11874882 chr17:31910113 ACCN1 0.27 6.38 0.33 5.61e-10 Response to iloperidone treatment (QT prolongation); LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg26570765 chr4:1273065 NA 0.31 6.15 0.32 2.16e-9 Obesity-related traits; LIHC cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg07424592 chr7:64974309 NA 0.79 9.02 0.44 1.37e-17 Diabetic kidney disease; LIHC cis rs1005277 0.579 rs2474586 chr10:38418882 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.96 -0.31 6.38e-9 Extrinsic epigenetic age acceleration; LIHC cis rs6582630 0.555 rs11613249 chr12:38519339 T/C cg26384229 chr12:38710491 ALG10B 0.7 9.86 0.47 2.39e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs908922 0.676 rs4845789 chr1:152528100 A/G cg20991723 chr1:152506922 NA 0.53 8.88 0.43 3.78e-17 Hair morphology; LIHC cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg12311346 chr5:56204834 C5orf35 -0.58 -7.55 -0.38 4.07e-13 Initial pursuit acceleration; LIHC trans rs78049276 0.688 rs73855809 chr4:148380348 G/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.59 -7.67 -0.38 1.76e-13 Pulse pressure; LIHC cis rs1559088 0.948 rs12610266 chr19:33581237 C/G cg27124370 chr19:33622961 WDR88 -0.53 -8.43 -0.41 9.54e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00828616 chr10:81838587 LOC219347;C10orf57 0.41 6.07 0.31 3.46e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2280018 1.000 rs2280018 chr16:15150833 A/C cg07549590 chr16:15018862 NA -0.34 -6.43 -0.33 4.25e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs769267 0.930 rs4808955 chr19:19552413 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 6.0 0.31 5.04e-9 Tonsillectomy; LIHC cis rs3008870 1.000 rs1137656 chr1:67451602 A/C cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs600806 0.888 rs444387 chr1:109851127 A/G cg02415029 chr1:110025642 ATXN7L2 -0.48 -5.97 -0.31 6.01e-9 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg19635926 chr16:89946313 TCF25 0.54 7.33 0.37 1.65e-12 Skin colour saturation; LIHC trans rs6489882 0.867 rs6489874 chr12:113367895 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs6429082 0.521 rs291390 chr1:235649678 T/C cg26050004 chr1:235667680 B3GALNT2 0.83 14.9 0.63 5.03e-39 Adiposity; LIHC cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg16405210 chr4:1374714 KIAA1530 -0.92 -15.37 -0.64 6.67e-41 Longevity; LIHC cis rs10504229 0.871 rs10504227 chr8:58162005 G/A cg21724239 chr8:58056113 NA 0.45 6.14 0.32 2.26e-9 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs763376 chr6:8492776 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg18252515 chr7:66147081 NA -1.26 -16.93 -0.68 3.82e-47 Diabetic kidney disease; LIHC cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg12310025 chr6:25882481 NA 0.59 7.96 0.4 2.5e-14 Blood metabolite levels; LIHC cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg24531977 chr5:56204891 C5orf35 -0.71 -10.13 -0.48 2.87e-21 Initial pursuit acceleration; LIHC cis rs644799 1.000 rs651445 chr11:95539122 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00498163 chr2:242821619 NA 0.37 6.24 0.32 1.29e-9 Cognitive function; LIHC cis rs35110281 0.744 rs230645 chr21:44918607 A/G cg04455712 chr21:45112962 RRP1B -0.46 -7.72 -0.39 1.32e-13 Mean corpuscular volume; LIHC trans rs8073060 0.545 rs3859282 chr17:34006111 T/C cg19694781 chr19:47549865 TMEM160 -1.25 -13.18 -0.58 2.36e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs950169 0.579 rs12912716 chr15:84664263 A/T cg17507749 chr15:85114479 UBE2QP1 0.64 5.89 0.3 9.33e-9 Schizophrenia; LIHC cis rs7412746 0.611 rs6660084 chr1:150748803 T/C cg17724175 chr1:150552817 MCL1 0.46 9.16 0.44 4.94e-18 Melanoma; LIHC cis rs2153535 0.580 rs1414342 chr6:8462552 A/G cg21535247 chr6:8435926 SLC35B3 0.62 8.13 0.4 7.76e-15 Motion sickness; LIHC cis rs6461049 0.765 rs10224497 chr7:2149967 A/G cg14004847 chr7:1930337 MAD1L1 -0.5 -7.54 -0.38 4.31e-13 Schizophrenia; LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg00800038 chr16:89945340 TCF25 -0.59 -9.61 -0.46 1.58e-19 Interleukin-17 levels; LIHC cis rs9911578 0.935 rs117819974 chr17:57002324 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs7727544 0.735 rs2569266 chr5:131706791 T/C cg24060327 chr5:131705240 SLC22A5 0.6 8.64 0.42 2.24e-16 Blood metabolite levels; LIHC cis rs10927875 0.864 rs6674071 chr1:16144855 G/C cg07117364 chr1:16154769 NA -0.4 -5.9 -0.3 8.51e-9 Dilated cardiomyopathy; LIHC cis rs9611565 0.802 rs132916 chr22:41806768 C/G cg03806693 chr22:41940476 POLR3H 0.56 7.52 0.38 4.94e-13 Vitiligo; LIHC cis rs2361718 0.631 rs2289539 chr17:78152119 T/C cg09238746 chr17:78121135 EIF4A3 -0.67 -11.03 -0.51 2.16e-24 Yeast infection; LIHC cis rs7107174 0.581 rs11237485 chr11:78126011 G/A cg02023728 chr11:77925099 USP35 0.41 7.41 0.37 9.96e-13 Testicular germ cell tumor; LIHC cis rs7508679 1.000 rs7248104 chr19:7224431 A/G cg09779027 chr19:7224513 INSR 0.31 6.73 0.34 7.14e-11 Hypothyroidism; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg21635948 chr2:53994617 LOC100302652;ASB3;CHAC2 0.3 6.13 0.31 2.47e-9 Calcium levels; LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg20295408 chr7:1910781 MAD1L1 -0.49 -7.01 -0.35 1.26e-11 Bipolar disorder and schizophrenia; LIHC cis rs10791097 0.694 rs11222370 chr11:130744767 T/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11676348 0.967 rs4674258 chr2:218990586 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.42 -5.79 -0.3 1.58e-8 Ulcerative colitis; LIHC cis rs12048904 0.505 rs10493936 chr1:101213335 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.55 -8.31 -0.41 2.27e-15 Multiple sclerosis; LIHC cis rs7914558 1.000 rs1890184 chr10:104748459 A/C cg15744005 chr10:104629667 AS3MT -0.37 -8.39 -0.41 1.32e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.68 0.38 1.68e-13 Height; LIHC cis rs2191566 0.821 rs59756444 chr19:44513656 C/G cg20607764 chr19:44506953 ZNF230 -0.43 -7.02 -0.35 1.19e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs10089 1.000 rs10463838 chr5:127518305 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.39 0.33 5.52e-10 Ileal carcinoids; LIHC cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg03396347 chr1:1875803 NA -0.48 -8.81 -0.43 6.61e-17 Body mass index; LIHC cis rs2303759 0.543 rs7255778 chr19:49906608 G/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.88 0.43 3.71e-17 Multiple sclerosis; LIHC cis rs6582630 0.502 rs1607867 chr12:38385463 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.38 0.41 1.36e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs57244997 1.000 rs57244997 chr6:162397506 G/A cg17173639 chr6:162384350 PARK2 -0.63 -7.32 -0.37 1.73e-12 Mosquito bite size; LIHC cis rs9611565 0.559 rs1006407 chr22:41972032 T/C cg06634786 chr22:41940651 POLR3H -0.81 -7.87 -0.39 4.79e-14 Vitiligo; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg26939375 chr7:64535504 NA 0.44 7.48 0.38 6.18e-13 Calcium levels; LIHC cis rs950169 0.922 rs8037078 chr15:84818871 A/G cg12863693 chr15:85201151 NMB -0.41 -5.78 -0.3 1.68e-8 Schizophrenia; LIHC cis rs9486715 0.867 rs4839828 chr6:96863326 G/A cg06623918 chr6:96969491 KIAA0776 0.85 14.95 0.63 2.96e-39 Headache; LIHC cis rs16828019 0.852 rs12729586 chr1:41522377 C/A cg03962019 chr1:41807865 NA 0.49 7.06 0.36 9.32e-12 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.659 rs11079357 chr17:56902778 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.24 0.58 1.36e-32 Cognitive test performance; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs4919694 1.000 rs10509760 chr10:104634107 A/G cg04362960 chr10:104952993 NT5C2 1.04 8.3 0.41 2.41e-15 Arsenic metabolism; LIHC cis rs10878977 0.586 rs732214 chr12:69815826 T/C cg17330252 chr12:69809627 NA 0.37 5.88 0.3 9.79e-9 Colorectal cancer; LIHC cis rs1568889 0.838 rs7943538 chr11:28288955 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 14.3 0.61 1.12e-36 Bipolar disorder; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02228635 chr1:93298093 RPL5 -0.51 -6.48 -0.33 3.19e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs1814175 0.645 rs1851844 chr11:50021773 T/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs10771431 0.967 rs7137443 chr12:9372029 C/T cg08997352 chr12:9597637 DDX12 -0.51 -7.4 -0.37 1.05e-12 Breast size; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg17512779 chr8:17104072 CNOT7;VPS37A -0.52 -6.12 -0.31 2.63e-9 Obesity-related traits; LIHC cis rs67460515 0.529 rs11712713 chr3:160852471 A/G cg03342759 chr3:160939853 NMD3 -0.56 -8.09 -0.4 1.05e-14 Parkinson's disease; LIHC cis rs36051895 0.554 rs10975027 chr9:5248827 G/A cg02405213 chr9:5042618 JAK2 -0.64 -10.29 -0.49 8.2e-22 Pediatric autoimmune diseases; LIHC cis rs6570726 0.935 rs391524 chr6:145823844 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs12701220 0.503 rs12702047 chr7:1132720 G/A cg00990874 chr7:1149470 C7orf50 -0.59 -5.8 -0.3 1.53e-8 Bronchopulmonary dysplasia; LIHC cis rs4252707 1 rs4252707 chr1:204508147 G/A cg17419461 chr1:204415978 PIK3C2B -0.4 -6.27 -0.32 1.06e-9 Glioma;Non-glioblastoma glioma; LIHC cis rs6570726 0.935 rs366621 chr6:145861275 A/G cg23711669 chr6:146136114 FBXO30 0.53 9.26 0.45 2.24e-18 Lobe attachment (rater-scored or self-reported); LIHC trans rs7668874 0.731 rs4339279 chr4:116751046 T/A cg08917878 chr5:172668965 NA -0.31 -6.15 -0.32 2.12e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs1005277 0.541 rs2505193 chr10:38394638 G/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs1669338 0.588 rs3864049 chr3:3186719 T/G cg16797762 chr3:3221439 CRBN -0.95 -8.41 -0.41 1.09e-15 White matter integrity; LIHC cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg10360323 chr17:41437877 NA 0.4 5.97 0.31 5.87e-9 Menopause (age at onset); LIHC cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg21782813 chr7:2030301 MAD1L1 -0.5 -8.62 -0.42 2.62e-16 Bipolar disorder and schizophrenia; LIHC cis rs3820500 0.543 rs1290539 chr1:118029601 T/G cg20383390 chr1:117909022 MAN1A2 0.46 5.93 0.31 7.33e-9 Pneumonia; LIHC cis rs651907 0.535 rs13094911 chr3:101519021 T/C cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs7923837 0.651 rs11187096 chr10:94369588 G/T cg25506282 chr10:94462361 NA 0.34 5.76 0.3 1.85e-8 Body mass index;Multiple sclerosis; LIHC cis rs6952809 0.532 rs6953297 chr7:2440874 C/G cg23289794 chr7:2394357 EIF3B -0.66 -6.57 -0.33 1.93e-10 Multiple sclerosis; LIHC cis rs2180341 0.842 rs7739679 chr6:127545428 G/A cg24812749 chr6:127587940 RNF146 1.0 13.27 0.58 1.01e-32 Breast cancer; LIHC cis rs4969178 0.965 rs12451715 chr17:76397334 A/C cg20026190 chr17:76395443 PGS1 0.46 7.29 0.37 2.11e-12 HDL cholesterol levels; LIHC trans rs7615952 0.932 rs13314869 chr3:125644669 G/A cg07211511 chr3:129823064 LOC729375 -0.85 -10.5 -0.49 1.5e-22 Blood pressure (smoking interaction); LIHC cis rs2839186 0.706 rs2839188 chr21:47692798 C/T cg05896524 chr21:47604654 C21orf56 0.43 6.13 0.31 2.43e-9 Testicular germ cell tumor; LIHC trans rs1728785 1.000 rs1749792 chr16:68569440 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.49 6.11 0.31 2.65e-9 Ulcerative colitis; LIHC cis rs722599 0.748 rs17093914 chr14:75363641 A/G cg11812906 chr14:75593930 NEK9 0.41 6.67 0.34 1.03e-10 IgG glycosylation; LIHC cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg18252515 chr7:66147081 NA -1.25 -16.5 -0.67 2.19e-45 Diabetic kidney disease; LIHC cis rs4407350 0.788 rs5764879 chr22:44920771 T/C cg11695653 chr22:44894386 LDOC1L -0.37 -6.16 -0.32 2.05e-9 Intelligence (multi-trait analysis); LIHC cis rs12479064 0.724 rs28369945 chr2:100080928 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.63 -6.7 -0.34 8.58e-11 Chronic sinus infection; LIHC cis rs1023500 0.505 rs134891 chr22:42675882 T/C cg00645731 chr22:42541494 CYP2D7P1 0.35 6.05 0.31 3.85e-9 Schizophrenia; LIHC cis rs12744310 1.000 rs12038924 chr1:41760317 C/T cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.72e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs636291 0.517 rs670666 chr1:10549380 C/T cg17425144 chr1:10567563 PEX14 -0.53 -10.69 -0.5 3.46e-23 Prostate cancer; LIHC cis rs9612 1.000 rs7246677 chr19:44248625 G/A cg08581076 chr19:44259116 C19orf61 0.67 8.54 0.42 4.35e-16 Exhaled nitric oxide output; LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.61 8.67 0.42 1.81e-16 Lymphocyte counts; LIHC cis rs907683 0.545 rs3755054 chr2:220280974 C/T cg15015639 chr2:220282977 DES 0.31 7.82 0.39 6.64e-14 Resting heart rate; LIHC cis rs1577917 1.000 rs12205548 chr6:86759770 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.21 -0.36 3.61e-12 Response to antipsychotic treatment; LIHC cis rs992157 0.764 rs2891077 chr2:219184430 A/C cg00012203 chr2:219082015 ARPC2 0.75 10.52 0.49 1.33e-22 Colorectal cancer; LIHC cis rs6964587 0.934 rs7798973 chr7:91588360 G/A cg17063962 chr7:91808500 NA 1.02 19.53 0.73 1.36e-57 Breast cancer; LIHC cis rs5997397 0.720 rs132549 chr22:29318724 C/T cg15103426 chr22:29168792 CCDC117 -0.48 -6.34 -0.32 7.29e-10 Red cell distribution width; LIHC cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg18357526 chr6:26021779 HIST1H4A -0.55 -6.55 -0.33 2.14e-10 Blood metabolite levels; LIHC cis rs6754311 0.593 rs10195620 chr2:136495619 A/T cg17750252 chr2:136567154 LCT 0.35 6.23 0.32 1.36e-9 Mosquito bite size; LIHC cis rs1801251 0.896 rs6719061 chr2:233695885 C/T cg25237894 chr2:233734115 C2orf82 -0.55 -10.35 -0.49 5.06e-22 Coronary artery disease; LIHC cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg25364880 chr3:44379878 C3orf23 0.46 6.63 0.34 1.28e-10 Depressive symptoms; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03130149 chr11:3819041 PGAP2;NUP98 0.44 6.46 0.33 3.56e-10 Pancreatic cancer; LIHC cis rs4407350 0.655 rs135623 chr22:44890672 C/T cg26276947 chr22:44892394 LDOC1L 0.33 6.22 0.32 1.45e-9 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg26338869 chr17:61819248 STRADA 0.6 8.61 0.42 2.73e-16 Prudent dietary pattern; LIHC cis rs921968 0.541 rs667251 chr2:219384384 C/G cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.48 -6.48 -0.33 3.17e-10 Bipolar disorder; LIHC cis rs4900538 0.855 rs762105 chr14:102830175 A/G cg18135206 chr14:102964638 TECPR2 -0.72 -11.29 -0.52 2.39e-25 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs798554 0.759 rs798495 chr7:2797267 T/C cg04166393 chr7:2884313 GNA12 0.45 6.24 0.32 1.28e-9 Height; LIHC cis rs921968 0.643 rs833083 chr2:219336959 A/T cg17980119 chr2:219472607 PLCD4 -0.37 -6.24 -0.32 1.3e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7937682 0.883 rs490492 chr11:111465150 C/T cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs7258465 0.965 rs8100767 chr19:18589088 T/C cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC cis rs6748734 1.000 rs4675868 chr2:241828542 A/C cg08694578 chr2:241835147 C2orf54 -0.51 -7.16 -0.36 4.88e-12 Urinary metabolites; LIHC cis rs765787 0.530 rs11070451 chr15:45533541 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs4727027 0.704 rs12704073 chr7:148905067 G/A cg23583168 chr7:148888333 NA -0.76 -11.65 -0.53 1.17e-26 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -10.41 -0.49 3.04e-22 Platelet count; LIHC cis rs425277 0.606 rs262663 chr1:2084598 T/C cg24578937 chr1:2090814 PRKCZ 0.32 5.98 0.31 5.52e-9 Height; LIHC cis rs2286885 1.000 rs2277159 chr9:129243383 C/T cg15282417 chr9:129245246 FAM125B 0.41 6.75 0.34 6.28e-11 Intraocular pressure; LIHC cis rs4638749 0.627 rs1522020 chr2:108833346 C/G cg06795125 chr2:108905320 SULT1C2 -0.3 -6.02 -0.31 4.52e-9 Blood pressure; LIHC cis rs57590327 0.679 rs13071810 chr3:81618478 T/C cg07356753 chr3:81810745 GBE1 -0.49 -6.69 -0.34 9.09e-11 Extraversion; LIHC cis rs12477438 0.765 rs7591992 chr2:99668954 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs11673344 0.830 rs3745770 chr19:37488565 C/G cg27390819 chr19:37464633 NA -0.5 -6.05 -0.31 3.82e-9 Obesity-related traits; LIHC cis rs950169 0.509 rs71395455 chr15:85153804 A/G cg17507749 chr15:85114479 UBE2QP1 0.69 7.81 0.39 6.89e-14 Schizophrenia; LIHC trans rs7246657 0.943 rs3745765 chr19:37854235 G/T cg10208301 chr11:6592745 DNHD1 0.47 6.76 0.34 5.93e-11 Coronary artery calcification; LIHC cis rs240764 0.658 rs6570922 chr6:101177262 C/T cg09795085 chr6:101329169 ASCC3 -0.53 -7.6 -0.38 2.8e-13 Neuroticism; LIHC cis rs11098499 0.954 rs2306455 chr4:120421969 G/A cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC cis rs79976124 0.797 rs77895756 chr6:66626782 C/T cg07460842 chr6:66804631 NA 0.64 6.84 0.35 3.58e-11 Type 2 diabetes; LIHC cis rs735860 0.712 rs6909592 chr6:53163090 C/G cg10236188 chr6:53219634 NA 0.41 7.48 0.37 6.36e-13 Glaucoma; LIHC cis rs4268898 0.722 rs12185638 chr2:24382030 C/G cg06627628 chr2:24431161 ITSN2 0.45 6.36 0.33 6.46e-10 Asthma; LIHC cis rs8067545 0.611 rs2158472 chr17:20171524 C/T cg13482628 chr17:19912719 NA -0.42 -6.79 -0.34 5.01e-11 Schizophrenia; LIHC cis rs2153535 0.580 rs2327057 chr6:8443319 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.51 0.53 3.97e-26 Motion sickness; LIHC cis rs397020 0.904 rs203547 chr20:1195245 T/A cg23117778 chr20:1206693 RAD21L1 0.37 6.34 0.32 7.29e-10 Multiple sclerosis; LIHC cis rs67478160 0.595 rs8022783 chr14:104245573 T/C cg08213375 chr14:104286397 PPP1R13B 0.66 12.88 0.57 3.24e-31 Schizophrenia; LIHC trans rs9929218 1.000 rs8044058 chr16:68807088 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.61 -0.42 2.81e-16 Colorectal cancer; LIHC cis rs6442522 0.772 rs2278962 chr3:15492786 A/T cg16303742 chr3:15540471 COLQ 0.43 7.25 0.37 2.76e-12 Uric acid levels; LIHC cis rs4660306 1.000 rs6667191 chr1:45982844 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.64 -7.58 -0.38 3.36e-13 Homocysteine levels; LIHC cis rs5769765 0.908 rs9627788 chr22:50300438 T/C cg02269571 chr22:50332266 NA -0.61 -8.71 -0.43 1.29e-16 Schizophrenia; LIHC cis rs74233809 1.000 rs74444347 chr10:104769275 A/C cg03493300 chr10:104813866 CNNM2 0.45 6.06 0.31 3.69e-9 Birth weight; LIHC trans rs983392 0.709 rs4492839 chr11:59986399 T/A cg17275991 chr19:58003312 ZNF419 0.44 6.27 0.32 1.08e-9 Alzheimer's disease (late onset); LIHC cis rs60871478 1.000 rs62432252 chr7:802886 C/G cg05535760 chr7:792225 HEATR2 0.79 11.04 0.51 1.98e-24 Cerebrospinal P-tau181p levels; LIHC cis rs9902453 0.967 rs4533341 chr17:28495672 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.88 0.43 3.97e-17 Coffee consumption (cups per day); LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg00960700 chr17:80709150 TBCD 0.36 5.98 0.31 5.73e-9 Glycated hemoglobin levels; LIHC cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg13395646 chr4:1353034 KIAA1530 -0.65 -9.37 -0.45 1.05e-18 Obesity-related traits; LIHC cis rs1707322 1.000 rs6682683 chr1:46342337 A/G cg06784218 chr1:46089804 CCDC17 0.35 6.36 0.32 6.65e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2404602 0.647 rs907594 chr15:77197745 C/A cg03037974 chr15:76606532 NA -0.57 -9.54 -0.46 2.74e-19 Blood metabolite levels; LIHC cis rs67311347 1.000 rs4246666 chr3:40407670 C/T cg24209194 chr3:40518798 ZNF619 0.42 5.97 0.31 6.06e-9 Renal cell carcinoma; LIHC cis rs1008375 1.000 rs2058338 chr4:17678600 A/G cg16339924 chr4:17578868 LAP3 -0.42 -6.13 -0.31 2.45e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9467773 1.000 rs6940053 chr6:26562122 C/T cg11502198 chr6:26597334 ABT1 0.44 6.47 0.33 3.46e-10 Intelligence (multi-trait analysis); LIHC cis rs11673344 0.864 rs12151313 chr19:37563211 C/T cg27390819 chr19:37464633 NA -0.51 -6.25 -0.32 1.23e-9 Obesity-related traits; LIHC cis rs644148 0.781 rs630469 chr19:44970167 T/C cg15540054 chr19:45004280 ZNF180 -0.77 -11.42 -0.53 8.63e-26 Personality dimensions; LIHC cis rs1865760 0.566 rs4529296 chr6:26083135 C/G cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs7089973 0.604 rs7914792 chr10:116591391 T/C cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9902453 0.845 rs10853135 chr17:28188675 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.98 0.54 7.29e-28 Coffee consumption (cups per day); LIHC cis rs2115630 0.645 rs3825877 chr15:85174631 G/A cg11189052 chr15:85197271 WDR73 -0.53 -8.23 -0.41 4e-15 P wave terminal force; LIHC cis rs7020830 0.894 rs13300951 chr9:37146627 A/G cg14294708 chr9:37120828 ZCCHC7 1.2 28.29 0.84 1.44e-91 Schizophrenia; LIHC cis rs748404 0.646 rs2253268 chr15:43800968 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.48 7.41 0.37 1.02e-12 Lung cancer; LIHC cis rs875971 1.000 rs778685 chr7:65836176 G/T cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs172166 0.694 rs9295760 chr6:28147385 G/A cg16479474 chr6:28041457 NA 0.38 6.43 0.33 4.2e-10 Cardiac Troponin-T levels; LIHC cis rs509477 0.962 rs562412 chr18:32576305 T/C cg23791764 chr18:32556832 MAPRE2 -0.53 -7.53 -0.38 4.44e-13 Cerebrospinal fluid AB1-42 levels; LIHC cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.26 0.45 2.33e-18 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25397718 chr9:140317786 EXD3;NOXA1 0.44 6.41 0.33 4.94e-10 Pancreatic cancer; LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg21782813 chr7:2030301 MAD1L1 -0.55 -9.94 -0.47 1.29e-20 Bipolar disorder and schizophrenia; LIHC cis rs7937890 0.598 rs10734225 chr11:14442994 C/G cg23387056 chr11:14280742 SPON1 -0.46 -6.01 -0.31 4.74e-9 Mitochondrial DNA levels; LIHC cis rs1538970 0.810 rs12067642 chr1:45927517 G/T cg05343316 chr1:45956843 TESK2 0.58 8.57 0.42 3.74e-16 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11411107 chr3:160473611 PPM1L 0.47 6.86 0.35 3.21e-11 Lung function (FEV1/FVC); LIHC cis rs2180341 1.000 rs9398837 chr6:127635217 G/A cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.4e-11 Diabetic kidney disease; LIHC cis rs597539 0.731 rs664229 chr11:68624483 C/G cg04772025 chr11:68637568 NA 0.45 5.85 0.3 1.16e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg11494091 chr17:61959527 GH2 0.45 8.13 0.4 7.75e-15 Prudent dietary pattern; LIHC cis rs240764 0.717 rs239236 chr6:101099217 A/G cg09795085 chr6:101329169 ASCC3 0.46 6.65 0.34 1.14e-10 Neuroticism; LIHC cis rs1816752 0.776 rs9511268 chr13:25018320 A/G cg02811702 chr13:24901961 NA 0.25 6.42 0.33 4.48e-10 Obesity-related traits; LIHC cis rs2228479 0.850 rs11645916 chr16:89835234 G/A cg00800038 chr16:89945340 TCF25 -0.61 -8.97 -0.44 1.96e-17 Skin colour saturation; LIHC cis rs4684776 0.867 rs11706990 chr3:11343663 G/A cg00170343 chr3:11313890 ATG7 -0.52 -7.21 -0.36 3.53e-12 Small vessel stroke; LIHC cis rs78456975 1.000 rs10208340 chr2:1563100 G/A cg01028140 chr2:1542097 TPO -0.53 -6.32 -0.32 8.09e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs651907 0.535 rs11716558 chr3:101528481 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs9527 0.637 rs7085104 chr10:104628873 A/G cg15744005 chr10:104629667 AS3MT -0.4 -9.0 -0.44 1.58e-17 Arsenic metabolism; LIHC cis rs2204008 0.777 rs8189597 chr12:38307739 G/C cg26384229 chr12:38710491 ALG10B -0.87 -10.8 -0.5 1.39e-23 Bladder cancer; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg05025164 chr4:1340916 KIAA1530 0.78 11.96 0.54 8.59e-28 Longevity; LIHC cis rs12602486 1.000 rs2285954 chr17:42232938 T/G cg08193365 chr17:42277699 NA 1.05 7.39 0.37 1.16e-12 Glycated hemoglobin levels; LIHC cis rs225245 0.791 rs3890901 chr17:34011322 A/C cg05299278 chr17:33885742 SLFN14 0.23 6.34 0.32 7.08e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs72653721 0.838 rs17764592 chr6:11003144 G/T cg13562911 chr6:11044106 ELOVL2 -0.5 -7.27 -0.37 2.51e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs5769765 0.565 rs8137232 chr22:50256885 G/C cg02269571 chr22:50332266 NA 0.7 8.05 0.4 1.38e-14 Schizophrenia; LIHC cis rs700651 0.789 rs2196176 chr2:198904914 A/G cg03934865 chr2:198174659 NA 0.47 6.56 0.33 1.95e-10 Intracranial aneurysm; LIHC cis rs11605275 1.000 rs73434177 chr11:20023995 G/A cg14835545 chr11:20032148 NAV2 -0.85 -7.68 -0.38 1.73e-13 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4665809 1.000 rs6729080 chr2:26301282 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.99 -0.44 1.69e-17 Gut microbiome composition (summer); LIHC cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg14393609 chr7:65229607 NA 0.44 6.58 0.34 1.81e-10 Aortic root size; LIHC cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg12379764 chr21:47803548 PCNT -0.58 -8.46 -0.42 7.96e-16 Testicular germ cell tumor; LIHC cis rs2033711 0.905 rs893186 chr19:58969179 C/A cg00825309 chr19:58991885 ZNF446 -0.69 -10.71 -0.5 2.72e-23 Uric acid clearance; LIHC cis rs72717009 0.825 rs12722986 chr1:161465420 A/G cg23840854 chr1:161414152 NA -0.57 -5.79 -0.3 1.55e-8 Rheumatoid arthritis; LIHC cis rs6598955 0.543 rs12122527 chr1:26549748 C/T cg04990556 chr1:26633338 UBXN11 0.73 10.63 0.5 5.51e-23 Obesity-related traits; LIHC cis rs2412488 0.893 rs2271559 chr4:54362676 A/G cg22241045 chr4:54363911 LNX1 0.46 7.64 0.38 2.15e-13 DNA methylation (variation); LIHC cis rs614226 0.938 rs7963543 chr12:120923948 C/A cg01236616 chr12:121019343 POP5 0.98 15.37 0.64 6.88e-41 Type 1 diabetes nephropathy; LIHC cis rs1691799 0.899 rs1168328 chr12:66729250 T/C cg16791601 chr12:66731901 HELB -0.56 -13.77 -0.6 1.21e-34 White blood cell count (basophil); LIHC cis rs7772486 0.727 rs11155442 chr6:146140725 T/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.2 -0.32 1.63e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg05484376 chr2:27715224 FNDC4 0.36 6.16 0.32 2.07e-9 Total body bone mineral density; LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg17178900 chr1:205818956 PM20D1 0.7 10.46 0.49 2.16e-22 Menarche (age at onset); LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs6977660 0.607 rs10243965 chr7:19797893 G/A cg07541023 chr7:19748670 TWISTNB 0.47 7.09 0.36 7.78e-12 Thyroid stimulating hormone; LIHC cis rs2573652 1.000 rs2581359 chr15:100513707 A/G cg09918751 chr15:100517450 ADAMTS17 -0.84 -15.41 -0.64 4.78e-41 Height; LIHC cis rs918629 0.761 rs3777166 chr5:95291056 G/C cg10483112 chr5:95245456 ELL2 -0.37 -6.22 -0.32 1.42e-9 IgG glycosylation; LIHC cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg25036284 chr2:26402008 FAM59B 0.5 5.79 0.3 1.61e-8 Gut microbiome composition (summer); LIHC cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg20607798 chr8:58055168 NA 0.72 8.07 0.4 1.19e-14 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.538 rs8078280 chr17:56473132 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.78 10.02 0.48 6.87e-21 Cognitive test performance; LIHC cis rs1866706 1.000 rs2099744 chr11:12866146 A/G cg25843174 chr11:12811716 TEAD1 0.3 6.31 0.32 8.53e-10 Intelligence (multi-trait analysis); LIHC cis rs6598163 0.712 rs10751695 chr12:132291061 A/C cg13251533 chr12:132286017 NA 0.48 8.81 0.43 6.25e-17 Migraine; LIHC cis rs9914988 0.887 rs12947735 chr17:27156866 A/T cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg07308232 chr7:1071921 C7orf50 -0.38 -6.12 -0.31 2.61e-9 Longevity;Endometriosis; LIHC trans rs916888 0.697 rs199516 chr17:44856485 C/T cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg11644478 chr21:40555479 PSMG1 0.86 11.04 0.51 1.9e-24 Cognitive function; LIHC cis rs2180341 1.000 rs9385419 chr6:127597591 A/G cg24812749 chr6:127587940 RNF146 1.05 15.71 0.65 2.87e-42 Breast cancer; LIHC cis rs2522056 1.000 rs2106854 chr5:131769174 C/T cg24060327 chr5:131705240 SLC22A5 0.58 8.02 0.4 1.7e-14 Lymphocyte counts;Fibrinogen; LIHC cis rs2075371 0.829 rs10954442 chr7:134007587 A/G cg11752832 chr7:134001865 SLC35B4 -0.46 -5.82 -0.3 1.37e-8 Mean platelet volume; LIHC cis rs2579500 0.807 rs11891926 chr2:97339781 A/G cg26665480 chr2:98280029 ACTR1B -0.42 -5.84 -0.3 1.22e-8 Eosinophil counts;Eosinophil percentage of white cells; LIHC cis rs9649465 0.967 rs11765790 chr7:123293152 A/C cg03229431 chr7:123269106 ASB15 -0.38 -8.04 -0.4 1.49e-14 Migraine; LIHC cis rs2645694 0.626 rs2645684 chr4:77819892 A/C cg06046430 chr4:77819534 ANKRD56 0.48 6.41 0.33 4.97e-10 Emphysema distribution in smoking; LIHC cis rs2637266 1.000 rs7478008 chr10:78355575 T/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs17401966 0.838 rs12120042 chr1:10345325 A/T cg15208524 chr1:10270712 KIF1B 0.38 5.86 0.3 1.09e-8 Hepatocellular carcinoma; LIHC cis rs9325144 0.600 rs10748442 chr12:38732939 A/T cg26384229 chr12:38710491 ALG10B 0.59 8.28 0.41 2.77e-15 Morning vs. evening chronotype; LIHC cis rs6121246 0.909 rs6060979 chr20:30417522 C/T cg13852791 chr20:30311386 BCL2L1 0.82 8.75 0.43 9.6e-17 Mean corpuscular hemoglobin; LIHC cis rs651907 0.535 rs35810977 chr3:101531380 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.08 0.51 1.43e-24 Colorectal cancer; LIHC cis rs5758511 0.680 rs58654759 chr22:42642576 T/C cg20195005 chr22:42527684 CYP2D6 0.31 5.85 0.3 1.12e-8 Birth weight; LIHC cis rs1552244 0.572 rs17032440 chr3:10169819 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 0.86 10.46 0.49 2.13e-22 Alzheimer's disease; LIHC cis rs1023500 0.552 rs133368 chr22:42463689 T/C cg15557168 chr22:42548783 NA -0.42 -6.53 -0.33 2.44e-10 Schizophrenia; LIHC cis rs1577917 1.000 rs955197 chr6:86729675 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -7.01 -0.35 1.26e-11 Response to antipsychotic treatment; LIHC cis rs765787 0.530 rs55771002 chr15:45541566 T/C cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC cis rs875971 0.545 rs2707851 chr7:66089165 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.35 -7.06 -0.36 9.33e-12 Aortic root size; LIHC cis rs9926296 0.607 rs11076629 chr16:89875259 T/C cg04287289 chr16:89883240 FANCA 0.52 8.43 0.41 9.46e-16 Vitiligo; LIHC cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg17554472 chr22:41940697 POLR3H 0.53 5.88 0.3 9.54e-9 Vitiligo; LIHC cis rs10871290 0.551 rs3863435 chr16:74465396 C/G cg01733217 chr16:74700730 RFWD3 -0.37 -6.46 -0.33 3.57e-10 Breast cancer; LIHC cis rs7818688 0.697 rs11782818 chr8:95978221 A/G cg16049864 chr8:95962084 TP53INP1 0.57 6.33 0.32 7.76e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7107174 0.892 rs10899487 chr11:78085474 G/A cg02023728 chr11:77925099 USP35 0.45 8.26 0.41 3.22e-15 Testicular germ cell tumor; LIHC trans rs11098499 0.542 rs10440343 chr4:120309787 G/C cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs11252926 0.537 rs61836851 chr10:447231 T/C cg16346588 chr10:242978 ZMYND11 0.38 5.88 0.3 9.97e-9 Psychosis in Alzheimer's disease; LIHC trans rs1994135 0.715 rs10844624 chr12:33691010 A/G cg26384229 chr12:38710491 ALG10B 0.51 6.78 0.34 5.17e-11 Resting heart rate; LIHC cis rs763121 0.853 rs2267395 chr22:39113903 C/T cg21395723 chr22:39101663 GTPBP1 0.37 6.19 0.32 1.7e-9 Menopause (age at onset); LIHC cis rs17376456 0.825 rs17314797 chr5:93234845 T/A cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs34172651 0.517 rs11639856 chr16:24788645 A/T cg04756594 chr16:24857601 SLC5A11 -0.51 -7.71 -0.38 1.41e-13 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08050352 chr16:46864715 C16orf87 0.42 6.42 0.33 4.58e-10 Lung function (FEV1/FVC); LIHC cis rs929354 0.772 rs1182360 chr7:157020550 C/G cg05182265 chr7:156933206 UBE3C -0.33 -6.2 -0.32 1.66e-9 Body mass index; LIHC cis rs12586317 0.582 rs731906 chr14:35604543 C/T cg05294307 chr14:35346193 BAZ1A -0.47 -6.94 -0.35 1.93e-11 Psoriasis; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg17707966 chr8:144718525 ZNF623 -0.48 -6.11 -0.31 2.67e-9 Lung function (FEV1); LIHC cis rs10752881 0.967 rs4652757 chr1:182974750 T/A ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC trans rs801193 1.000 rs17566701 chr7:66193183 T/C cg26939375 chr7:64535504 NA 0.39 6.12 0.31 2.63e-9 Aortic root size; LIHC cis rs6546550 0.935 rs1531025 chr2:70055505 G/T cg02498382 chr2:70120550 SNRNP27 -0.4 -6.52 -0.33 2.5e-10 Prevalent atrial fibrillation; LIHC cis rs7615952 0.611 rs2947646 chr3:125593602 C/T cg05084668 chr3:125655381 ALG1L 0.65 8.25 0.41 3.45e-15 Blood pressure (smoking interaction); LIHC cis rs9911578 0.967 rs2567892 chr17:56668929 T/C cg12560992 chr17:57184187 TRIM37 0.97 17.74 0.69 2.19e-50 Intelligence (multi-trait analysis); LIHC trans rs561341 0.739 rs8070554 chr17:30216868 A/T cg20587970 chr11:113659929 NA 0.53 6.95 0.35 1.85e-11 Hip circumference adjusted for BMI; LIHC trans rs1814175 0.519 rs10839291 chr11:49514321 G/A cg03929089 chr4:120376271 NA 0.7 10.26 0.49 1.06e-21 Height; LIHC cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC trans rs11098499 0.909 rs10014719 chr4:120320715 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.75 0.47 5.57e-20 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06742493 chr19:13056745 RAD23A -0.44 -6.16 -0.32 2.08e-9 Pancreatic cancer; LIHC cis rs12887734 0.524 rs4906363 chr14:104210239 G/A cg24130564 chr14:104152367 KLC1 -0.42 -6.92 -0.35 2.26e-11 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs17001868 0.568 rs742140 chr22:40781586 G/A cg07138101 chr22:40742427 ADSL 0.55 6.42 0.33 4.68e-10 Mammographic density (dense area); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21012729 chr14:51297401 NIN 0.42 6.35 0.32 6.99e-10 Lung function (FEV1/FVC); LIHC cis rs2060793 0.506 rs10741658 chr11:14924736 T/C cg25251204 chr11:14927456 NA 0.42 5.94 0.31 6.84e-9 Vitamin D levels; LIHC cis rs7224685 1.000 rs1377807 chr17:4045440 C/G cg09597638 chr17:3907349 NA 0.63 8.28 0.41 2.83e-15 Type 2 diabetes; LIHC cis rs2370759 0.945 rs10508773 chr10:32575444 C/T cg01819863 chr10:32635814 EPC1 1.11 16.42 0.66 4.34e-45 Sexual dysfunction (female); LIHC cis rs1008375 1.000 rs555 chr4:17625658 A/G cg02297831 chr4:17616191 MED28 0.48 7.46 0.37 7.18e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9660180 0.620 rs3817856 chr1:1663831 C/T cg27541892 chr1:1571801 CDK11B -0.58 -8.55 -0.42 4.04e-16 Body mass index; LIHC cis rs1538970 0.962 rs2298018 chr1:45813441 T/C cg05343316 chr1:45956843 TESK2 0.54 8.08 0.4 1.11e-14 Platelet count; LIHC cis rs4919087 1.000 rs4919090 chr10:99088419 C/G cg25902810 chr10:99078978 FRAT1 -0.66 -9.91 -0.47 1.63e-20 Monocyte count; LIHC cis rs2404602 0.716 rs7179142 chr15:76698268 G/A cg23625390 chr15:77176239 SCAPER 0.37 6.22 0.32 1.42e-9 Blood metabolite levels; LIHC cis rs6762 0.748 rs28735718 chr11:839629 A/G cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.78 -0.47 4.28e-20 Mean platelet volume; LIHC cis rs7633770 0.643 rs58413466 chr3:46689154 G/T cg11219411 chr3:46661640 NA -0.36 -5.95 -0.31 6.55e-9 Coronary artery disease; LIHC cis rs9790314 0.936 rs466399 chr3:161091194 G/T cg04691961 chr3:161091175 C3orf57 -0.45 -7.32 -0.37 1.75e-12 Morning vs. evening chronotype; LIHC cis rs67478160 0.643 rs8005225 chr14:104300151 C/T cg08213375 chr14:104286397 PPP1R13B -0.64 -12.74 -0.57 1.08e-30 Schizophrenia; LIHC cis rs244293 1.000 rs244316 chr17:53215223 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.45 -0.37 7.67e-13 Menarche (age at onset); LIHC trans rs57221529 0.709 rs72706612 chr5:561198 C/T cg25482853 chr8:67687455 SGK3 0.67 6.66 0.34 1.09e-10 Lung disease severity in cystic fibrosis; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg26115276 chr5:178977181 RUFY1 -0.52 -6.84 -0.35 3.76e-11 Myopia (pathological); LIHC cis rs7587476 0.784 rs34112702 chr2:215696002 A/G cg04004882 chr2:215674386 BARD1 0.57 7.81 0.39 6.92e-14 Neuroblastoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07280387 chr12:120763487 PLA2G1B 0.49 7.13 0.36 5.9e-12 Cognitive function; LIHC cis rs151997 0.925 rs27847 chr5:50176197 G/T cg06027927 chr5:50259733 NA 0.57 7.57 0.38 3.59e-13 Callous-unemotional behaviour; LIHC cis rs11122272 0.705 rs2790879 chr1:231534389 A/C cg06096015 chr1:231504339 EGLN1 0.51 9.2 0.45 3.52e-18 Hemoglobin concentration; LIHC cis rs2932538 0.922 rs3790611 chr1:113067792 A/G cg22162597 chr1:113214053 CAPZA1 0.69 10.73 0.5 2.47e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7258465 0.931 rs875396 chr19:18611147 A/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.2e-13 Breast cancer; LIHC trans rs459571 0.920 rs417142 chr9:136891370 G/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.61 -9.44 -0.45 6.01e-19 Platelet distribution width; LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC trans rs801193 0.660 rs2659914 chr7:66156914 C/T cg10756647 chr7:56101905 PSPH 0.47 6.95 0.35 1.81e-11 Aortic root size; LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg11494091 chr17:61959527 GH2 -0.55 -10.55 -0.5 1.04e-22 Prudent dietary pattern; LIHC cis rs711245 0.637 rs11894187 chr2:36781708 T/A cg01206211 chr2:36825736 FEZ2 0.45 7.29 0.37 2.14e-12 Height; LIHC cis rs6570726 0.791 rs414297 chr6:145887556 C/T cg23711669 chr6:146136114 FBXO30 0.65 11.58 0.53 2.16e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2273669 0.667 rs12206834 chr6:109303967 T/G cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs7071206 0.947 rs10509391 chr10:79422369 G/A cg07817648 chr10:79422355 NA -0.33 -7.02 -0.35 1.21e-11 Bone mineral density; LIHC cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.06 -0.36 9.52e-12 Bipolar disorder; LIHC cis rs6964587 0.869 rs10256780 chr7:91527176 T/A cg17063962 chr7:91808500 NA -0.96 -17.88 -0.7 5.74e-51 Breast cancer; LIHC cis rs3106136 0.843 rs1991316 chr4:95268272 G/T cg11021082 chr4:95130006 SMARCAD1 0.41 7.63 0.38 2.41e-13 Capecitabine sensitivity; LIHC cis rs2997447 0.669 rs61776624 chr1:26474580 A/C cg19633962 chr1:26362018 EXTL1 -0.69 -6.47 -0.33 3.44e-10 QRS complex (12-leadsum); LIHC cis rs7552404 1.000 rs1498315 chr1:76159225 G/A cg10523679 chr1:76189770 ACADM 0.66 9.11 0.44 7.16e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2404602 0.716 rs12437627 chr15:76845050 T/C cg03037974 chr15:76606532 NA 0.79 16.05 0.66 1.36e-43 Blood metabolite levels; LIHC cis rs968567 0.539 rs174549 chr11:61571382 A/G cg27386326 chr11:61587980 NA -0.68 -14.17 -0.61 3.61e-36 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.69 0.8 5.26e-78 Prudent dietary pattern; LIHC cis rs7772486 0.686 rs1292337 chr6:145967807 A/G cg23711669 chr6:146136114 FBXO30 -0.62 -11.19 -0.52 5.8e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs7208859 0.673 rs55658077 chr17:29156519 A/G cg13385521 chr17:29058706 SUZ12P 0.82 7.99 0.4 2.16e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs16858210 0.874 rs1879256 chr3:183609061 A/G cg25686905 chr3:183603175 PARL -0.48 -9.02 -0.44 1.35e-17 Menopause (age at onset); LIHC cis rs17685 0.523 rs10246583 chr7:75746667 C/A cg16684958 chr7:75615977 POR 0.51 8.59 0.42 3.18e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4820539 0.966 rs2157709 chr22:23457420 T/C cg14186256 chr22:23484241 RTDR1 0.93 19.36 0.72 6.34e-57 Bone mineral density; LIHC cis rs11792861 0.888 rs11794648 chr9:111829792 C/T cg13535736 chr9:111863775 C9orf5 -0.4 -6.17 -0.32 1.91e-9 Menarche (age at onset); LIHC cis rs2439831 0.867 rs16957630 chr15:43642780 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC cis rs929354 0.772 rs3802125 chr7:156970563 A/C cg17757837 chr7:157058334 UBE3C 0.71 10.95 0.51 3.9e-24 Body mass index; LIHC cis rs7615952 0.641 rs12495947 chr3:125771698 C/T cg05084668 chr3:125655381 ALG1L -0.41 -6.38 -0.33 5.63e-10 Blood pressure (smoking interaction); LIHC cis rs360798 0.512 rs6545973 chr2:63089434 C/T cg17519650 chr2:63277830 OTX1 0.45 7.1 0.36 7.43e-12 Coronary artery disease; LIHC cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg02034447 chr16:89574710 SPG7 0.47 7.38 0.37 1.25e-12 Multiple myeloma (IgH translocation); LIHC trans rs3794271 0.706 rs9971816 chr12:20826911 C/T cg13245912 chr11:63449340 RTN3 -0.43 -6.79 -0.34 5.07e-11 Response to TNF-alpha inhibitors in rheumatoid arthritis; LIHC cis rs17685 0.884 rs6978677 chr7:75636240 C/T cg16684958 chr7:75615977 POR 0.5 8.57 0.42 3.56e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10876993 0.890 rs1585781 chr12:58056701 T/G cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.57 -0.33 1.86e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8180040 0.701 rs12491473 chr3:46989904 G/A cg02527881 chr3:46936655 PTH1R 0.32 6.42 0.33 4.68e-10 Colorectal cancer; LIHC cis rs7937890 0.559 rs1116739 chr11:14489182 G/C cg02886208 chr11:14281011 SPON1 -0.47 -6.64 -0.34 1.23e-10 Mitochondrial DNA levels; LIHC cis rs477692 1.000 rs580745 chr10:131414401 G/A cg19680672 chr10:131412579 MGMT -0.44 -6.66 -0.34 1.1e-10 Response to temozolomide; LIHC cis rs8027181 0.682 rs4777546 chr15:73104435 C/T cg25996835 chr15:72978165 BBS4;HIGD2B -0.44 -6.84 -0.35 3.67e-11 Triglyceride levels; LIHC cis rs7086627 0.515 rs10887894 chr10:82209952 A/G cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs72781680 0.898 rs72786278 chr2:24063243 C/T cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs763121 0.962 rs1980455 chr22:38925719 A/C cg06022373 chr22:39101656 GTPBP1 0.6 11.06 0.51 1.62e-24 Menopause (age at onset); LIHC cis rs4268898 0.722 rs2288072 chr2:24390517 G/A cg06627628 chr2:24431161 ITSN2 0.44 6.34 0.32 7.07e-10 Asthma; LIHC cis rs1200821 0.529 rs4934856 chr10:37807847 T/C cg00409905 chr10:38381863 ZNF37A 0.46 7.25 0.36 2.8e-12 Hemostatic factors and hematological phenotypes; LIHC cis rs17685 0.712 rs4552844 chr7:75718095 A/G cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03120789 chr1:20208808 OTUD3 0.44 6.63 0.34 1.29e-10 Cognitive function; LIHC cis rs10463316 0.894 rs4099169 chr5:150766526 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -6.08 -0.31 3.19e-9 Metabolite levels (Pyroglutamine); LIHC cis rs2857078 0.654 rs4793083 chr17:42312973 C/T cg08499158 chr17:42289980 UBTF 0.47 7.73 0.39 1.18e-13 Red cell distribution width;Reticulocyte count; LIHC cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg21782813 chr7:2030301 MAD1L1 0.48 8.24 0.41 3.64e-15 Bipolar disorder and schizophrenia; LIHC cis rs861318 0.640 rs2793844 chr1:159016967 A/G cg11003133 chr1:159046391 AIM2 0.32 6.27 0.32 1.08e-9 Obesity-related traits; LIHC cis rs3770081 1.000 rs58898686 chr2:86216909 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -8.52 -0.42 5.32e-16 Facial emotion recognition (sad faces); LIHC cis rs2839186 1.000 rs2839181 chr21:47685939 A/G cg12016809 chr21:47604291 C21orf56 0.45 6.63 0.34 1.34e-10 Testicular germ cell tumor; LIHC cis rs2760061 0.819 rs708115 chr1:228198046 C/T cg02753203 chr1:228287806 NA 0.48 7.97 0.4 2.43e-14 Diastolic blood pressure; LIHC trans rs4332037 0.707 rs11763813 chr7:1896690 C/T cg11693508 chr17:37793320 STARD3 0.61 6.23 0.32 1.41e-9 Bipolar disorder; LIHC trans rs459571 0.959 rs392134 chr9:136909008 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.58 -9.03 -0.44 1.26e-17 Platelet distribution width; LIHC cis rs6582630 0.502 rs7311700 chr12:38463232 T/A cg13010199 chr12:38710504 ALG10B 0.52 6.11 0.31 2.75e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7829975 0.606 rs10112585 chr8:8795030 A/T cg06636001 chr8:8085503 FLJ10661 -0.42 -6.7 -0.34 8.52e-11 Mood instability; LIHC cis rs7412746 0.621 rs11204749 chr1:150929563 G/A cg15448220 chr1:150897856 SETDB1 0.38 5.98 0.31 5.6e-9 Melanoma; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg04013166 chr16:89971882 TCF25 0.56 7.37 0.37 1.3e-12 Skin colour saturation; LIHC cis rs4788570 0.625 rs4788810 chr16:71621637 C/T cg06353428 chr16:71660113 MARVELD3 -1.35 -12.76 -0.57 9.25e-31 Intelligence (multi-trait analysis); LIHC cis rs9467773 1.000 rs1884948 chr6:26567988 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.75 0.6 1.5e-34 Intelligence (multi-trait analysis); LIHC cis rs918629 0.567 rs1841010 chr5:95251911 G/C cg10483112 chr5:95245456 ELL2 -0.36 -6.72 -0.34 7.41e-11 IgG glycosylation; LIHC cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.82 0.35 4.07e-11 Gut microbiome composition (summer); LIHC cis rs968567 0.638 rs7943728 chr11:61547068 G/A cg06781209 chr11:61594997 FADS2 -0.63 -5.86 -0.3 1.08e-8 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs12701220 0.604 rs34904312 chr7:1135883 G/A cg04498913 chr7:1135747 C7orf50 0.45 7.24 0.36 2.9e-12 Bronchopulmonary dysplasia; LIHC cis rs3768617 0.811 rs12138049 chr1:182979546 C/T ch.1.3577855R chr1:183094577 LAMC1 0.48 7.55 0.38 4.03e-13 Fuchs's corneal dystrophy; LIHC cis rs1577917 1.000 rs6923148 chr6:86767786 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.32 0.32 8.3e-10 Response to antipsychotic treatment; LIHC cis rs7520050 0.966 rs4376778 chr1:46288846 C/G cg03146154 chr1:46216737 IPP -0.4 -6.54 -0.33 2.27e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2832077 0.527 rs2705690 chr21:30239245 T/A cg24692254 chr21:30365293 RNF160 0.45 6.83 0.35 3.99e-11 Cognitive test performance; LIHC cis rs7927771 0.965 rs3817335 chr11:47643891 T/A cg20135002 chr11:47629003 NA -0.57 -9.85 -0.47 2.63e-20 Subjective well-being; LIHC cis rs7246657 0.943 rs1373991 chr19:37838911 T/C cg23950597 chr19:37808831 NA -0.44 -5.97 -0.31 5.93e-9 Coronary artery calcification; LIHC cis rs11958404 0.615 rs7704746 chr5:157450601 C/G cg05962755 chr5:157440814 NA 0.59 7.83 0.39 6.15e-14 IgG glycosylation; LIHC cis rs6060717 0.698 rs8123175 chr20:34609872 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -8.04 -0.4 1.5e-14 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs12579753 0.913 rs12579018 chr12:82231943 T/C cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC trans rs800082 0.734 rs1726536 chr3:144249504 G/T cg24215973 chr2:240111563 HDAC4 0.44 6.43 0.33 4.29e-10 Smoking behavior; LIHC cis rs55702914 0.742 rs34555121 chr2:198166053 C/T cg10820045 chr2:198174542 NA 0.41 6.19 0.32 1.76e-9 Major depression and alcohol dependence; LIHC cis rs801193 0.844 rs7779971 chr7:66161790 T/C cg14393609 chr7:65229607 NA 0.38 5.91 0.3 8.22e-9 Aortic root size; LIHC cis rs2153535 0.580 rs1832101 chr6:8460177 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.35 0.41 1.77e-15 Motion sickness; LIHC cis rs1005277 0.557 rs176887 chr10:38406094 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg05325390 chr16:23464715 COG7 -0.46 -7.19 -0.36 4.01e-12 Body mass index; LIHC cis rs5758659 0.967 rs5751250 chr22:42639645 T/G cg19513890 chr22:42538836 CYP2D7P1 -0.39 -7.61 -0.38 2.7e-13 Cognitive function; LIHC cis rs4970988 0.640 rs7524734 chr1:150655686 C/T cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Urate levels; LIHC cis rs35110281 0.805 rs3788062 chr21:44991159 C/T cg04455712 chr21:45112962 RRP1B 0.45 7.76 0.39 1.01e-13 Mean corpuscular volume; LIHC cis rs9359856 0.564 rs55722352 chr6:90365853 C/T cg13799429 chr6:90582589 CASP8AP2 -0.66 -6.15 -0.32 2.18e-9 Bipolar disorder; LIHC cis rs807669 0.903 rs756651 chr22:19179367 T/C cg02655711 chr22:19163373 SLC25A1 0.73 11.2 0.52 5.32e-25 Metabolite levels; LIHC cis rs9325144 0.555 rs2387843 chr12:38711203 T/C cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.42e-14 Morning vs. evening chronotype; LIHC cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7089973 0.604 rs7919649 chr10:116609576 T/C cg03647239 chr10:116582469 FAM160B1 0.46 6.77 0.34 5.78e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg27572855 chr1:25598939 RHD 0.4 8.68 0.43 1.59e-16 Erythrocyte sedimentation rate; LIHC trans rs75804782 0.521 rs72993033 chr2:239382882 A/G cg01134436 chr17:81009848 B3GNTL1 0.86 7.2 0.36 3.82e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs11663156 0.921 rs67915568 chr18:50921507 C/T cg24270629 chr18:50823537 DCC -0.49 -6.69 -0.34 9.18e-11 Intelligence (multi-trait analysis); LIHC trans rs1961637 0.603 rs1550423 chr2:223885812 C/T cg22481606 chr17:56429567 SUPT4H1 -0.4 -6.65 -0.34 1.19e-10 Oropharynx cancer; LIHC cis rs9811920 0.609 rs2452320 chr3:99645216 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs7523273 0.517 rs2985106 chr1:207892033 T/G cg22525895 chr1:207977042 MIR29B2 -0.53 -7.72 -0.39 1.28e-13 Schizophrenia; LIHC trans rs2243480 1.000 rs4718309 chr7:65627764 G/C cg10756647 chr7:56101905 PSPH -1.1 -13.4 -0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs6815814 0.950 rs5743593 chr4:38802913 A/G cg06935464 chr4:38784597 TLR10 0.48 7.44 0.37 8.27e-13 Breast cancer; LIHC cis rs9674544 0.646 rs8069452 chr17:47140999 A/G cg07075026 chr17:47091521 IGF2BP1 0.42 5.84 0.3 1.24e-8 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); LIHC cis rs17685 0.753 rs10952840 chr7:75772878 C/T cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs367615 0.512 rs414724 chr5:108670421 A/G cg17395555 chr5:108820864 NA 0.3 6.35 0.32 6.81e-10 Colorectal cancer (SNP x SNP interaction); LIHC cis rs611744 0.967 rs671139 chr8:109191260 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24141115 chr1:52831603 CC2D1B 0.45 6.33 0.32 7.65e-10 Lung function (FEV1/FVC); LIHC cis rs2204008 0.693 rs12372025 chr12:38202028 G/A cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.25e-8 Bladder cancer; LIHC cis rs1211375 0.628 rs3859141 chr16:245079 T/C cg08400316 chr16:204221 HBZ 0.38 5.96 0.31 6.42e-9 Hematology traits;Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg18357526 chr6:26021779 HIST1H4A 0.58 8.04 0.4 1.49e-14 Blood metabolite levels; LIHC cis rs941873 0.805 rs10762860 chr10:81117794 C/G cg11057378 chr10:81107060 PPIF 0.36 5.84 0.3 1.23e-8 Height; LIHC cis rs2153535 0.580 rs7741403 chr6:8530578 C/T cg23788917 chr6:8435910 SLC35B3 -0.62 -8.79 -0.43 7.58e-17 Motion sickness; LIHC cis rs11971779 0.616 rs6965143 chr7:139026608 C/G cg07862535 chr7:139043722 LUC7L2 0.58 10.03 0.48 6.38e-21 Diisocyanate-induced asthma; LIHC cis rs2370759 1.000 rs11008865 chr10:32574842 C/T cg05361325 chr10:32636312 EPC1 -0.52 -6.41 -0.33 4.77e-10 Sexual dysfunction (female); LIHC cis rs11628318 0.614 rs10140498 chr14:103154191 A/G cg12046867 chr14:103022105 NA 0.49 6.96 0.35 1.73e-11 Platelet count; LIHC cis rs9649213 0.593 rs6970990 chr7:97925382 T/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.85 -0.3 1.17e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs7618501 0.933 rs1128535 chr3:49866392 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.8 14.65 0.62 4.81e-38 Intelligence (multi-trait analysis); LIHC cis rs7584330 0.554 rs76980036 chr2:238426750 G/A cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs13064411 0.696 rs6787026 chr3:113162117 A/G cg18753928 chr3:113234510 CCDC52 -0.44 -6.2 -0.32 1.6e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs7474896 1.000 rs35258216 chr10:38018220 G/A cg25427524 chr10:38739819 LOC399744 -0.5 -6.29 -0.32 9.83e-10 Obesity (extreme); LIHC cis rs9790314 0.871 rs336551 chr3:161109720 T/C cg03342759 chr3:160939853 NMD3 -0.64 -7.87 -0.39 4.67e-14 Morning vs. evening chronotype; LIHC cis rs753778 0.570 rs4961335 chr8:142209142 A/G cg18755752 chr8:142205143 DENND3 -0.32 -5.88 -0.3 9.94e-9 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs1355223 0.583 rs2941060 chr11:34879154 G/A cg11058730 chr11:34937778 PDHX;APIP 0.74 12.63 0.56 2.74e-30 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2979489 0.891 rs2915625 chr8:30382651 G/A cg26383811 chr8:30366931 RBPMS -0.71 -11.11 -0.52 1.06e-24 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs6442522 0.772 rs2278961 chr3:15492807 G/A cg16303742 chr3:15540471 COLQ 0.43 7.24 0.36 2.97e-12 Uric acid levels; LIHC cis rs6089584 0.627 rs6089303 chr20:60565797 G/A cg06108461 chr20:60628389 TAF4 -0.53 -6.93 -0.35 2.08e-11 Body mass index; LIHC cis rs12701220 0.655 rs7784403 chr7:1153077 G/A cg04025307 chr7:1156635 C7orf50 0.53 6.94 0.35 1.99e-11 Bronchopulmonary dysplasia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13378865 chr6:26660005 ZNF322A 0.41 6.11 0.31 2.78e-9 Lung function (FEV1/FVC); LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs4919694 1.000 rs10509758 chr10:104681710 T/C cg04362960 chr10:104952993 NT5C2 0.79 7.86 0.39 5.13e-14 Arsenic metabolism; LIHC cis rs12744310 0.887 rs12047439 chr1:41809640 A/T cg03962019 chr1:41807865 NA 0.38 6.17 0.32 1.96e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11122272 0.735 rs2749711 chr1:231537543 G/A cg06096015 chr1:231504339 EGLN1 0.49 9.17 0.44 4.55e-18 Hemoglobin concentration; LIHC trans rs4290604 0.748 rs4621125 chr2:238080214 G/A cg15676719 chr1:167598521 RCSD1 -0.48 -6.23 -0.32 1.33e-9 Asthma; LIHC cis rs6500602 0.793 rs4785964 chr16:4484613 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.45 6.34 0.32 7.28e-10 Schizophrenia; LIHC cis rs4808199 0.895 rs2285628 chr19:19467996 T/A cg03709012 chr19:19516395 GATAD2A 1.03 16.41 0.66 4.83e-45 Nonalcoholic fatty liver disease; LIHC cis rs1215050 0.765 rs783947 chr4:99012943 T/C cg05340658 chr4:99064831 C4orf37 -0.4 -6.21 -0.32 1.51e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs5753618 0.561 rs5753543 chr22:31685458 G/A cg07713946 chr22:31675144 LIMK2 -0.44 -7.91 -0.39 3.52e-14 Colorectal cancer; LIHC cis rs9368481 0.502 rs3933232 chr6:26877446 T/C cg18867708 chr6:26865862 GUSBL1 0.55 8.3 0.41 2.37e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs11690462 0.817 rs7571948 chr2:26542155 C/A cg26119090 chr2:26468346 HADHA;HADHB 0.48 6.82 0.35 4.11e-11 Coronary artery disease; LIHC cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg06634786 chr22:41940651 POLR3H -0.82 -8.91 -0.43 3.12e-17 Vitiligo; LIHC cis rs921968 0.648 rs538483 chr2:219458656 T/C cg18887096 chr2:219472410 PLCD4 0.36 6.32 0.32 8.27e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs36051895 0.623 rs7025005 chr9:5261794 T/C cg02405213 chr9:5042618 JAK2 -0.57 -9.22 -0.45 3.02e-18 Pediatric autoimmune diseases; LIHC cis rs743757 1.000 rs1107265 chr3:50431995 A/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.53 8.38 0.41 1.38e-15 Diastolic blood pressure; LIHC cis rs8081395 0.711 rs1292034 chr17:57989860 G/A cg13753209 chr17:57696993 CLTC 0.38 5.82 0.3 1.33e-8 White blood cell count; LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg26338869 chr17:61819248 STRADA 0.61 8.9 0.43 3.37e-17 Prudent dietary pattern; LIHC cis rs11583043 0.831 rs6667818 chr1:101412313 A/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.13 0.31 2.41e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9326248 1.000 rs7946257 chr11:117053165 A/G cg10130564 chr11:117069849 TAGLN 0.35 5.97 0.31 5.91e-9 Blood protein levels; LIHC cis rs818427 0.896 rs351770 chr5:112199199 C/A cg07820702 chr5:112228657 REEP5 0.36 5.76 0.3 1.92e-8 Total body bone mineral density; LIHC cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.33 5.99 0.31 5.41e-9 Calcium levels; LIHC cis rs903552 0.800 rs6598479 chr15:102005913 A/C cg06707286 chr15:102010195 PCSK6 -0.48 -6.72 -0.34 7.56e-11 Diabetic kidney disease; LIHC cis rs875971 1.000 rs6961155 chr7:65933295 T/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs1215050 0.791 rs1727278 chr4:98853576 A/G cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.61e-8 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02732134 chr10:101732382 DNMBP 0.4 6.98 0.35 1.5e-11 Cognitive function; LIHC cis rs921968 0.541 rs578450 chr2:219401237 C/T cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs798554 0.757 rs1182176 chr7:2874601 A/G cg04166393 chr7:2884313 GNA12 0.47 6.32 0.32 8.15e-10 Height; LIHC cis rs11080107 0.542 rs894606 chr17:27909352 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.48 7.14 0.36 5.56e-12 Coronary artery disease; LIHC cis rs734999 0.588 rs2843402 chr1:2528682 T/C cg18854424 chr1:2615690 NA -0.33 -7.25 -0.36 2.83e-12 Ulcerative colitis; LIHC cis rs17854409 1.000 rs66956644 chr20:61484499 T/C cg06598544 chr20:61472147 COL9A3 -0.81 -7.65 -0.38 2.01e-13 Obesity-related traits; LIHC cis rs2257205 0.667 rs7221142 chr17:56758786 A/G cg12560992 chr17:57184187 TRIM37 0.71 7.79 0.39 8.05e-14 Pancreatic cancer; LIHC cis rs919433 0.680 rs2244271 chr2:198286581 C/T cg10820045 chr2:198174542 NA 0.55 8.83 0.43 5.41e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs258324 0.790 rs2162944 chr16:89717670 G/C cg03597607 chr16:89714999 CHMP1A -0.46 -5.98 -0.31 5.51e-9 Height; LIHC cis rs760762 0.636 rs12480916 chr20:39932356 T/G cg06424997 chr20:39929561 ZHX3 0.36 5.94 0.31 6.86e-9 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; LIHC cis rs10464366 0.746 rs62442210 chr7:39146328 G/T cg20302533 chr7:39170763 POU6F2 0.37 6.74 0.34 6.65e-11 IgG glycosylation; LIHC cis rs992157 0.643 rs10191283 chr2:219056755 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.77 12.51 0.56 7.9e-30 Colorectal cancer; LIHC cis rs244293 0.965 rs244365 chr17:53187401 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.47 -0.37 6.93e-13 Menarche (age at onset); LIHC cis rs3540 0.533 rs2256097 chr15:90971331 A/T cg22089800 chr15:90895588 ZNF774 0.56 7.83 0.39 6.23e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs9993613 0.967 rs35631249 chr4:73443865 C/A cg15102770 chr4:73434591 ADAMTS3 0.38 6.15 0.32 2.11e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs459571 0.606 rs457420 chr9:136909261 A/G cg13789015 chr9:136890014 NCRNA00094 -0.39 -7.63 -0.38 2.42e-13 Platelet distribution width; LIHC cis rs9503598 0.502 rs6939192 chr6:3430282 C/T cg00476032 chr6:3446245 SLC22A23 -0.32 -5.86 -0.3 1.08e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg13047869 chr3:10149882 C3orf24 0.51 5.84 0.3 1.23e-8 Alzheimer's disease; LIHC trans rs11039798 0.588 rs12278284 chr11:48612063 G/C cg15704280 chr7:45808275 SEPT13 0.57 6.31 0.32 8.6e-10 Axial length; LIHC trans rs6600671 0.934 rs11249431 chr1:121286203 A/G cg09829573 chr1:144692074 NBPF9 0.42 7.03 0.36 1.16e-11 Hip geometry; LIHC cis rs765787 0.556 rs2413778 chr15:45539397 C/A cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC cis rs644799 0.601 rs568878 chr11:95578694 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.64 10.57 0.5 8.8e-23 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs801193 1.000 rs3778909 chr7:66255646 G/C cg00343986 chr7:65444356 GUSB 0.41 6.1 0.31 2.9e-9 Aortic root size; LIHC cis rs61990749 0.597 rs6574402 chr14:78267950 C/A cg23188588 chr14:78226832 SNW1;C14orf178 0.6 9.82 0.47 3.28e-20 Fibroblast growth factor basic levels; LIHC cis rs2404602 0.647 rs12914196 chr15:76941361 C/T cg03037974 chr15:76606532 NA -0.6 -9.93 -0.47 1.38e-20 Blood metabolite levels; LIHC cis rs2050392 0.517 rs593400 chr10:30762088 A/G cg25182066 chr10:30743637 MAP3K8 0.63 10.48 0.49 1.8e-22 Inflammatory bowel disease; LIHC cis rs9596863 0.851 rs1379832 chr13:54429818 C/T ch.13.53330881F chr13:54432880 NA 0.45 5.98 0.31 5.65e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs738321 0.701 rs4821754 chr22:38581503 A/G cg25457927 chr22:38595422 NA 0.39 9.46 0.46 5.12e-19 Breast cancer; LIHC trans rs35110281 0.666 rs2838348 chr21:45107285 C/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO -0.47 -6.31 -0.32 8.81e-10 Mean corpuscular volume; LIHC cis rs17376456 0.825 rs10075217 chr5:93176774 C/G cg25358565 chr5:93447407 FAM172A 0.97 9.55 0.46 2.49e-19 Diabetic retinopathy; LIHC cis rs727505 1.000 rs28392553 chr7:124442944 C/T cg23710748 chr7:124431027 NA -0.35 -6.19 -0.32 1.73e-9 Lewy body disease; LIHC cis rs1577917 0.771 rs9362237 chr6:86409064 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.68 13.24 0.58 1.37e-32 Response to antipsychotic treatment; LIHC cis rs7116495 1.000 rs3886589 chr11:71669487 G/T cg26138937 chr11:71823887 C11orf51 -0.82 -8.17 -0.4 6.02e-15 Severe influenza A (H1N1) infection; LIHC cis rs3008870 1.000 rs3008874 chr1:67431365 A/T cg02640540 chr1:67518911 SLC35D1 0.43 5.96 0.31 6.44e-9 Lymphocyte percentage of white cells; LIHC cis rs1348850 0.632 rs12471621 chr2:178502353 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.87 0.39 4.83e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg26818010 chr10:134567672 INPP5A -0.79 -9.72 -0.47 7.2e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1865760 1.000 rs3799371 chr6:25912816 A/G cg03264133 chr6:25882463 NA 0.39 5.74 0.3 2.07e-8 Height; LIHC cis rs9916302 0.904 rs6503507 chr17:37525274 C/T cg03013999 chr17:37608204 MED1 -0.35 -5.88 -0.3 9.53e-9 Glomerular filtration rate (creatinine); LIHC cis rs916888 0.773 rs538628 chr17:44787313 G/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.92 0.35 2.29e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs933688 0.532 rs10072084 chr5:90539203 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.41 6.62 0.34 1.37e-10 Smoking behavior; LIHC cis rs8064299 0.597 rs2016126 chr17:72784932 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.73 12.85 0.57 4.17e-31 Monocyte count; LIHC cis rs2075371 0.932 rs1862052 chr7:133981227 G/A cg20476274 chr7:133979776 SLC35B4 0.71 9.53 0.46 3.07e-19 Mean platelet volume; LIHC cis rs61990749 0.597 rs12887606 chr14:78200620 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.63 10.5 0.49 1.59e-22 Fibroblast growth factor basic levels; LIHC cis rs5769707 0.681 rs2071902 chr22:50034538 G/C cg07959070 chr22:50026188 C22orf34 -0.35 -8.49 -0.42 6.29e-16 Monocyte count;Monocyte percentage of white cells; LIHC trans rs875971 1.000 rs6460292 chr7:65810075 G/A cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.2e-10 Aortic root size; LIHC cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg10862848 chr6:42927986 GNMT -0.3 -6.77 -0.34 5.75e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1355223 0.583 rs1828298 chr11:34870439 A/G cg11058730 chr11:34937778 PDHX;APIP 0.74 12.63 0.56 2.74e-30 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6912958 0.547 rs451089 chr6:88041859 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.92 0.51 5.13e-24 Monocyte percentage of white cells; LIHC cis rs4900538 0.855 rs72698597 chr14:102868633 C/T cg18135206 chr14:102964638 TECPR2 -0.71 -10.95 -0.51 3.86e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs12477438 0.765 rs6542846 chr2:99563654 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.44 -0.49 2.4e-22 Chronic sinus infection; LIHC cis rs10876993 0.890 rs799575 chr12:58069107 A/G cg18357645 chr12:58087776 OS9 0.51 8.38 0.41 1.37e-15 Celiac disease or Rheumatoid arthritis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07501049 chr1:981392 AGRN 0.48 7.34 0.37 1.6e-12 Cognitive function; LIHC cis rs2576037 0.526 rs2187092 chr18:44526798 A/C cg19077165 chr18:44547161 KATNAL2 -0.43 -6.54 -0.33 2.21e-10 Personality dimensions; LIHC cis rs7129220 0.588 rs7950718 chr11:10086624 C/A cg01453529 chr11:10209919 SBF2 -0.41 -7.44 -0.37 8.44e-13 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs10791097 0.720 rs6590517 chr11:130733505 C/T cg12179176 chr11:130786555 SNX19 0.79 12.74 0.57 1.1e-30 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2439831 1.000 rs2444029 chr15:43737484 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.94 0.44 2.42e-17 Lung cancer in ever smokers; LIHC cis rs67311347 0.955 rs6773383 chr3:40377412 A/T cg24209194 chr3:40518798 ZNF619 0.43 6.24 0.32 1.31e-9 Renal cell carcinoma; LIHC cis rs7100689 0.725 rs10736340 chr10:82061071 C/T cg01528321 chr10:82214614 TSPAN14 0.87 11.96 0.54 8.55e-28 Post bronchodilator FEV1; LIHC cis rs7726839 0.526 rs11960159 chr5:568685 C/T cg09021430 chr5:549028 NA -0.42 -8.84 -0.43 5.19e-17 Obesity-related traits; LIHC cis rs870825 0.616 rs1401358 chr4:185640057 C/T cg04058563 chr4:185651563 MLF1IP 0.61 7.0 0.35 1.32e-11 Blood protein levels; LIHC cis rs763121 0.813 rs2179143 chr22:39037984 A/G cg21395723 chr22:39101663 GTPBP1 0.34 5.73 0.3 2.16e-8 Menopause (age at onset); LIHC cis rs4891159 0.724 rs690401 chr18:74108576 C/T cg24786174 chr18:74118243 ZNF516 0.79 14.02 0.6 1.38e-35 Longevity; LIHC cis rs807669 0.934 rs762523 chr22:19180589 A/G cg02655711 chr22:19163373 SLC25A1 0.73 11.2 0.52 5.32e-25 Metabolite levels; LIHC cis rs225245 0.817 rs225297 chr17:33924587 G/A cg05299278 chr17:33885742 SLFN14 0.22 6.0 0.31 5.1e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06620762 chr15:76136437 UBE2Q2 0.41 6.35 0.32 6.82e-10 Cognitive function; LIHC cis rs875971 0.830 rs6967708 chr7:65657313 A/T cg18876405 chr7:65276391 NA -0.36 -6.37 -0.33 5.93e-10 Aortic root size; LIHC cis rs7107174 1.000 rs55761949 chr11:77993860 A/G cg02023728 chr11:77925099 USP35 0.51 9.79 0.47 4.25e-20 Testicular germ cell tumor; LIHC trans rs916888 0.821 rs199505 chr17:44859410 A/G cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9303401 0.659 rs35828828 chr17:56718205 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.31 0.55 4.45e-29 Cognitive test performance; LIHC cis rs7224314 1.000 rs57672368 chr17:65358688 G/C cg01507342 chr17:65387096 PITPNC1 -0.46 -5.96 -0.31 6.17e-9 Diisocyanate-induced asthma; LIHC cis rs769267 0.965 rs6511026 chr19:19391402 C/T cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs4906332 0.811 rs2756138 chr14:103996733 C/G cg19000871 chr14:103996768 TRMT61A 0.56 9.48 0.46 4.43e-19 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10283155 chr3:42642604 NKTR 0.45 6.4 0.33 5.11e-10 Lung function (FEV1/FVC); LIHC cis rs2033711 0.654 rs734380 chr19:58898963 A/C cg00825309 chr19:58991885 ZNF446 -0.44 -6.52 -0.33 2.54e-10 Uric acid clearance; LIHC trans rs6058796 1.000 rs6057614 chr20:31255800 C/T cg02600331 chr11:130417168 NA 0.35 7.51 0.38 5.18e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs1008375 1.000 rs4642241 chr4:17617111 T/C cg15017067 chr4:17643749 FAM184B 0.34 5.85 0.3 1.13e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11971779 0.941 rs7800795 chr7:139080348 A/G cg07862535 chr7:139043722 LUC7L2 0.69 11.24 0.52 3.71e-25 Diisocyanate-induced asthma; LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg04234412 chr22:24373322 LOC391322 -0.63 -8.74 -0.43 1.05e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs116248771 0.739 rs4680454 chr3:158377913 C/T cg16708174 chr3:158430962 RARRES1 0.48 6.38 0.33 5.61e-10 diarrhoeal disease at age 2; LIHC cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg06481639 chr22:41940642 POLR3H 0.71 7.12 0.36 6.44e-12 Vitiligo; LIHC trans rs11165623 0.602 rs7527155 chr1:97016690 T/C cg10631902 chr5:14652156 NA -0.25 -6.28 -0.32 1.04e-9 Hip circumference;Waist circumference; LIHC cis rs7552404 0.889 rs380075 chr1:76106961 T/A cg10523679 chr1:76189770 ACADM -0.66 -9.21 -0.45 3.36e-18 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13819586 chr14:24685205 MDP1 0.5 7.23 0.36 3.28e-12 Lung function (FEV1/FVC); LIHC cis rs1707322 0.721 rs28501477 chr1:46199084 A/G cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 9.3 0.45 1.69e-18 Platelet count; LIHC cis rs921968 0.565 rs6436072 chr2:219598095 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs3785309 0.519 rs7197253 chr16:276549 C/T cg14162552 chr9:139744532 PHPT1 0.61 6.54 0.33 2.21e-10 Immature fraction of reticulocytes; LIHC cis rs7095944 0.614 rs3824765 chr10:126433570 C/G cg08799069 chr10:126477246 METTL10 -0.37 -6.48 -0.33 3.29e-10 Asthma; LIHC cis rs875971 0.825 rs66981195 chr7:66079035 C/A cg11764359 chr7:65958608 NA -0.78 -13.64 -0.59 4.13e-34 Aortic root size; LIHC cis rs1008375 0.932 rs2302394 chr4:17641188 A/G cg16339924 chr4:17578868 LAP3 0.51 6.77 0.34 5.51e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs763014 1.000 rs7205409 chr16:642610 A/G cg07343612 chr16:622815 PIGQ -0.77 -12.52 -0.56 7.04e-30 Height; LIHC cis rs2836950 0.545 rs2836940 chr21:40588696 T/C cg17971929 chr21:40555470 PSMG1 -0.38 -5.79 -0.3 1.62e-8 Menarche (age at onset); LIHC trans rs4596713 0.538 rs10114369 chr9:71799697 T/A cg16512924 chr15:28394682 HERC2 0.39 6.23 0.32 1.33e-9 Headache; LIHC cis rs116248771 0.739 rs116045655 chr3:158335368 G/A cg16708174 chr3:158430962 RARRES1 0.47 6.28 0.32 1.04e-9 diarrhoeal disease at age 2; LIHC cis rs11626933 0.959 rs2149649 chr14:90774974 A/G cg14092571 chr14:90743983 NA 0.87 14.18 0.61 3.16e-36 Gut microbiota (bacterial taxa); LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg22903471 chr2:27725779 GCKR -0.46 -7.92 -0.39 3.38e-14 Total body bone mineral density; LIHC cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Electroencephalogram traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16404460 chr10:89622595 PTEN;KILLIN 0.48 6.51 0.33 2.6200000000000003e-10 Pancreatic cancer; LIHC cis rs929354 0.772 rs6967764 chr7:156994964 C/T cg05182265 chr7:156933206 UBE3C -0.32 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs288342 0.832 rs288306 chr2:183652286 C/T cg02625481 chr2:183667124 NA -0.29 -6.11 -0.31 2.67e-9 Recurrent major depressive disorder; LIHC cis rs8078723 0.714 rs9915252 chr17:38145088 C/G cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.29 0.52 2.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs13118159 0.801 rs1128427 chr4:1330759 T/C cg13395646 chr4:1353034 KIAA1530 -0.41 -6.04 -0.31 4.09e-9 Longevity; LIHC cis rs9486719 0.901 rs13206547 chr6:97006942 T/C cg06623918 chr6:96969491 KIAA0776 -0.71 -7.26 -0.37 2.62e-12 Migraine;Coronary artery disease; LIHC cis rs8044995 0.563 rs8058517 chr16:68379860 A/G cg05110241 chr16:68378359 PRMT7 0.71 8.36 0.41 1.62e-15 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18964732 chr1:165737775 TMCO1 0.46 6.62 0.34 1.41e-10 Cognitive function; LIHC cis rs875971 0.862 rs10263690 chr7:65766453 G/C cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs3106136 0.967 rs12499309 chr4:95171284 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.93 -0.39 3.04e-14 Capecitabine sensitivity; LIHC cis rs9814567 0.964 rs9833753 chr3:134213665 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.13 -0.55 2.01e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg19318889 chr4:1322082 MAEA -0.48 -7.99 -0.4 2.05e-14 Obesity-related traits; LIHC cis rs9896933 0.830 rs8074277 chr17:80789628 T/C cg20578329 chr17:80767326 TBCD -0.66 -6.64 -0.34 1.24e-10 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs713477 1.000 rs12886860 chr14:55911150 G/C cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.64e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs10464366 0.519 rs6974609 chr7:39219149 C/T cg20302533 chr7:39170763 POU6F2 0.33 6.08 0.31 3.17e-9 IgG glycosylation; LIHC cis rs9733 0.628 rs7540874 chr1:150702663 A/C cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs1801251 1.000 rs7587309 chr2:233705702 G/T cg25237894 chr2:233734115 C2orf82 -0.58 -11.51 -0.53 3.96e-26 Coronary artery disease; LIHC cis rs4906332 1.000 rs17680085 chr14:103953154 T/C cg04998671 chr14:104000505 TRMT61A -0.46 -6.24 -0.32 1.29e-9 Coronary artery disease; LIHC cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg06634786 chr22:41940651 POLR3H -0.79 -8.69 -0.43 1.58e-16 Vitiligo; LIHC cis rs2361718 0.631 rs4889989 chr17:78151860 C/G cg09238746 chr17:78121135 EIF4A3 0.64 10.61 0.5 6.26e-23 Yeast infection; LIHC cis rs9303401 0.659 rs12602389 chr17:56779778 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC trans rs7395662 0.500 rs1304199 chr11:48699032 A/G cg15704280 chr7:45808275 SEPT13 -0.51 -7.69 -0.38 1.55e-13 HDL cholesterol; LIHC cis rs4788570 0.615 rs2032918 chr16:71703436 T/G cg06353428 chr16:71660113 MARVELD3 1.39 14.48 0.62 2.14e-37 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11668638 chr6:42952412 PPP2R5D 0.48 7.1 0.36 7.46e-12 Pancreatic cancer; LIHC cis rs1348850 0.668 rs2365619 chr2:178497366 A/G cg27490568 chr2:178487706 NA -0.67 -8.69 -0.43 1.53e-16 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg07677032 chr17:61819896 STRADA -0.39 -5.73 -0.3 2.18e-8 Prudent dietary pattern; LIHC cis rs1577917 1.000 rs12215037 chr6:86727631 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.93 -0.35 2.1e-11 Response to antipsychotic treatment; LIHC cis rs4803468 0.935 rs284660 chr19:41932084 G/T cg09537434 chr19:41945824 ATP5SL -1.01 -20.37 -0.74 5.93e-61 Height; LIHC cis rs765787 0.530 rs4774550 chr15:45542312 C/T cg25801113 chr15:45476975 SHF 0.37 6.37 0.33 6.28e-10 Uric acid levels; LIHC cis rs66569888 0.754 rs6719028 chr2:106895212 T/C cg23109721 chr2:106886537 NA 0.71 6.83 0.35 3.99e-11 Facial morphology (factor 23); LIHC cis rs9611565 0.503 rs5996062 chr22:42167464 C/G cg06634786 chr22:41940651 POLR3H 0.73 7.39 0.37 1.15e-12 Vitiligo; LIHC cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg24675658 chr1:53192096 ZYG11B 0.63 10.19 0.48 1.83e-21 Monocyte count; LIHC cis rs870825 0.655 rs10013685 chr4:185617785 C/T cg04058563 chr4:185651563 MLF1IP 0.77 7.67 0.38 1.81e-13 Blood protein levels; LIHC cis rs694739 0.930 rs574087 chr11:64102948 A/G cg23796481 chr11:64053134 BAD;GPR137 0.6 8.2 0.41 4.8e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs11971779 0.680 rs10229249 chr7:139052510 A/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs116248771 0.690 rs73156439 chr3:158359462 G/C cg16708174 chr3:158430962 RARRES1 0.48 6.42 0.33 4.46e-10 diarrhoeal disease at age 2; LIHC trans rs73389468 1 rs73389468 chr10:134295815 C/T cg20713102 chr15:85144157 ZSCAN2 -0.85 -6.27 -0.32 1.11e-9 Periodontitis (CDC/AAP); LIHC cis rs6061231 0.675 rs755726 chr20:60962624 T/C cg03945807 chr20:60948434 NA 0.37 6.27 0.32 1.11e-9 Colorectal cancer; LIHC cis rs3758785 0.737 rs12270338 chr11:94147464 A/C cg21580213 chr11:94231278 ANKRD49 0.36 6.27 0.32 1.11e-9 Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy); LIHC cis rs7520050 0.831 rs61783170 chr1:46256329 T/C cg03146154 chr1:46216737 IPP -0.41 -6.63 -0.34 1.3100000000000001e-10 Red blood cell count;Reticulocyte count; LIHC cis rs589448 0.967 rs2617834 chr12:69753365 T/C cg14784868 chr12:69753453 YEATS4 0.99 23.08 0.78 1.05e-71 Cerebrospinal fluid biomarker levels; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg21548813 chr6:291882 DUSP22 -0.56 -7.52 -0.38 4.77e-13 Menopause (age at onset); LIHC trans rs2749592 0.550 rs9733309 chr10:37882405 G/A cg27523141 chr10:43048294 ZNF37B -0.37 -6.3 -0.32 8.92e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6788895 1.000 rs73006998 chr3:150464271 G/A cg09723797 chr3:150481914 SIAH2 0.78 9.87 0.47 2.17e-20 Breast cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03350042 chr15:40733177 BAHD1 0.45 6.59 0.34 1.63e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21767703 chr1:236444768 ERO1LB -0.51 -6.67 -0.34 1.05e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs2096176 0.606 rs11819592 chr10:26422407 G/A cg01396774 chr2:218299024 DIRC3 -0.31 -6.09 -0.31 3.04e-9 Obesity-related traits; LIHC cis rs9918079 0.560 rs4698402 chr4:15629803 G/A cg21329975 chr4:15471214 CC2D2A -0.38 -5.77 -0.3 1.75e-8 Obesity-related traits; LIHC cis rs4253772 0.591 rs12167567 chr22:46659942 G/C cg09491104 chr22:46646882 C22orf40 -0.69 -8.11 -0.4 9.08e-15 LDL cholesterol;Cholesterol, total; LIHC cis rs7635838 0.617 rs13071193 chr3:11284226 G/T cg00170343 chr3:11313890 ATG7 -0.59 -9.42 -0.45 6.98e-19 HDL cholesterol; LIHC cis rs7772486 0.875 rs9373485 chr6:146401429 A/T cg13319975 chr6:146136371 FBXO30 -0.38 -6.18 -0.32 1.77e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7223966 1.000 rs8064261 chr17:61705212 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.62 0.34 1.37e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs34172651 0.917 rs200539 chr16:24735178 T/C cg04756594 chr16:24857601 SLC5A11 -0.47 -7.33 -0.37 1.73e-12 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.56 0.62 1.09e-37 Prudent dietary pattern; LIHC cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.42 0.45 6.79e-19 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11444135 chr17:72428287 GPRC5C 0.47 6.88 0.35 2.94e-11 Lung function (FEV1/FVC); LIHC trans rs3780486 0.874 rs10813955 chr9:33141791 C/T cg04842962 chr6:43655489 MRPS18A 1.07 25.2 0.81 6.09e-80 IgG glycosylation; LIHC cis rs9467773 1.000 rs6456733 chr6:26566804 C/T cg09904177 chr6:26538194 HMGN4 0.65 13.65 0.59 3.68e-34 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01669482 chr16:25043131 NA 0.5 6.91 0.35 2.31e-11 Pancreatic cancer; LIHC cis rs1144333 0.850 rs1144342 chr1:76284364 A/G cg10523679 chr1:76189770 ACADM -0.46 -6.63 -0.34 1.29e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs801193 0.967 rs3800823 chr7:66147110 C/A cg18252515 chr7:66147081 NA 0.43 5.71 0.3 2.45e-8 Aortic root size; LIHC cis rs6088590 0.931 rs6088624 chr20:33436852 T/A cg24642439 chr20:33292090 TP53INP2 0.74 9.77 0.47 4.79e-20 Coronary artery disease; LIHC cis rs8077889 0.956 rs58242860 chr17:41847300 T/C cg26893861 chr17:41843967 DUSP3 0.88 9.85 0.47 2.52e-20 Triglycerides; LIHC trans rs12310956 0.532 rs1525904 chr12:33962448 T/C cg26384229 chr12:38710491 ALG10B 0.53 7.28 0.37 2.27e-12 Morning vs. evening chronotype; LIHC cis rs60871478 0.898 rs62432897 chr7:825429 A/G cg04727924 chr7:799746 HEATR2 -0.61 -8.55 -0.42 4.2e-16 Cerebrospinal P-tau181p levels; LIHC cis rs4906332 1.000 rs10459573 chr14:103925457 A/C cg04998671 chr14:104000505 TRMT61A -0.45 -6.18 -0.32 1.86e-9 Coronary artery disease; LIHC cis rs7918232 1.000 rs7918232 chr10:27369162 A/G cg14442939 chr10:27389572 ANKRD26 0.69 6.86 0.35 3.22e-11 Breast cancer; LIHC cis rs4319547 0.585 rs7953007 chr12:122816977 A/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.36 -0.37 1.4e-12 Body mass index; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg21747090 chr2:27597821 SNX17 -0.46 -7.0 -0.35 1.37e-11 Menopause (age at onset); LIHC cis rs9649465 0.967 rs2402666 chr7:123285478 A/T cg03229431 chr7:123269106 ASB15 -0.38 -8.24 -0.41 3.79e-15 Migraine; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg12315363 chr17:34136012 TAF15 -0.42 -6.43 -0.33 4.34e-10 Systolic blood pressure; LIHC cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg12310025 chr6:25882481 NA -0.63 -9.02 -0.44 1.33e-17 Blood metabolite levels; LIHC cis rs9768139 0.733 rs34173461 chr7:158122175 C/G cg25566285 chr7:158114605 PTPRN2 0.23 6.12 0.31 2.55e-9 Calcium levels; LIHC cis rs2108622 0.545 rs59140933 chr19:15975308 C/T cg13772218 chr19:15982569 NA 0.34 7.23 0.36 3.19e-12 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg06873352 chr17:61820015 STRADA 0.74 13.58 0.59 7.01e-34 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC cis rs6754311 0.638 rs2322659 chr2:136555659 A/G cg25344623 chr2:136566232 LCT 0.38 7.3 0.37 1.98e-12 Mosquito bite size; LIHC cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg13395646 chr4:1353034 KIAA1530 0.41 5.86 0.3 1.08e-8 Longevity; LIHC cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg10360323 chr17:41437877 NA 0.41 6.09 0.31 3.1e-9 Menopause (age at onset); LIHC cis rs929354 0.742 rs6956046 chr7:156962874 G/A cg16102536 chr7:156981717 UBE3C 0.35 5.92 0.3 7.91e-9 Body mass index; LIHC cis rs8177253 0.509 rs6762415 chr3:133478557 T/G cg12373951 chr3:133503437 NA 0.45 7.29 0.37 2.21e-12 Iron status biomarkers; LIHC cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg07061783 chr6:25882402 NA -0.49 -6.23 -0.32 1.41e-9 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg21782813 chr7:2030301 MAD1L1 -0.46 -7.68 -0.38 1.7e-13 Bipolar disorder and schizophrenia; LIHC cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg24642844 chr7:1081250 C7orf50 -0.95 -9.26 -0.45 2.25e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2279817 1.000 rs1339800 chr1:18020201 C/G cg21791023 chr1:18019539 ARHGEF10L -0.61 -8.53 -0.42 4.81e-16 Neuroticism; LIHC cis rs507080 0.922 rs582630 chr11:118562799 C/A cg04173919 chr11:118528438 PHLDB1 0.35 6.58 0.34 1.77e-10 Serum metabolite levels; LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg14671364 chr1:107599128 PRMT6 -0.54 -7.93 -0.39 3.08e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2153535 0.580 rs1577472 chr6:8486215 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs1997103 0.954 rs6593236 chr7:55410992 C/T cg17469321 chr7:55412551 NA 0.48 6.95 0.35 1.81e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2760061 0.626 rs1636192 chr1:228124688 A/G cg02753203 chr1:228287806 NA -0.47 -7.56 -0.38 3.74e-13 Diastolic blood pressure; LIHC trans rs11722228 0.508 rs3796826 chr4:10092728 G/A cg26043149 chr18:55253948 FECH 0.95 13.92 0.6 3.3e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs1204798 0.589 rs6909133 chr6:116601532 A/G cg23214565 chr6:116600728 DSE;TSPYL1 -0.42 -6.16 -0.32 2e-9 Dental caries; LIHC cis rs400736 0.602 rs11121090 chr1:8168634 A/G cg25007680 chr1:8021821 PARK7 0.55 8.23 0.41 4.09e-15 Response to antidepressants and depression; LIHC cis rs317689 0.718 rs315130 chr12:69761444 T/C cg19645103 chr12:69753606 YEATS4 -0.45 -6.15 -0.32 2.17e-9 Response to diuretic therapy; LIHC cis rs17125944 0.615 rs1998779 chr14:53295950 T/A cg00686598 chr14:53173677 PSMC6 -0.82 -9.68 -0.46 9.22e-20 Alzheimer's disease (late onset); LIHC cis rs2797369 0.546 rs11963911 chr6:101308421 T/C cg12253828 chr6:101329408 ASCC3 0.44 6.37 0.33 6.13e-10 Renal function-related traits (eGRFcrea); LIHC cis rs4906332 1.000 rs7155980 chr14:103922419 C/G cg19000871 chr14:103996768 TRMT61A -0.45 -7.78 -0.39 8.9e-14 Coronary artery disease; LIHC cis rs8180040 0.764 rs13062022 chr3:47169375 G/A cg27129171 chr3:47204927 SETD2 0.68 11.98 0.54 7.74e-28 Colorectal cancer; LIHC cis rs1577917 1.000 rs1415753 chr6:86753074 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.04 -0.48 5.98e-21 Response to antipsychotic treatment; LIHC cis rs9318086 0.904 rs9580769 chr13:24439724 T/C cg25267304 chr13:24462978 PCOTH;MIPEP -0.54 -10.88 -0.51 6.85e-24 Myopia (pathological); LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg06873352 chr17:61820015 STRADA 0.74 13.21 0.58 1.74e-32 Prudent dietary pattern; LIHC cis rs2576037 0.583 rs504668 chr18:44410749 T/C cg19077165 chr18:44547161 KATNAL2 -0.47 -7.11 -0.36 6.68e-12 Personality dimensions; LIHC cis rs6121246 0.529 rs6120862 chr20:30199459 T/C cg13852791 chr20:30311386 BCL2L1 0.76 6.82 0.35 4.02e-11 Mean corpuscular hemoglobin; LIHC cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg11062466 chr8:58055876 NA 0.39 5.72 0.3 2.34e-8 Developmental language disorder (linguistic errors); LIHC cis rs7267979 1.000 rs2297496 chr20:25295787 T/C cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.72 -0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7089973 0.668 rs61868024 chr10:116637939 A/G cg03647239 chr10:116582469 FAM160B1 0.47 6.86 0.35 3.3e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.62 0.38 2.44e-13 Prudent dietary pattern; LIHC cis rs1577917 0.839 rs1838956 chr6:86565263 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.47 -0.37 6.61e-13 Response to antipsychotic treatment; LIHC cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.81 8.07 0.4 1.18e-14 Platelet count; LIHC cis rs34779708 0.966 rs7913615 chr10:35422957 T/G cg04310649 chr10:35416472 CREM -0.43 -5.9 -0.3 8.97e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1801251 0.964 rs6748027 chr2:233629552 T/C cg08000102 chr2:233561755 GIGYF2 0.77 11.55 0.53 2.9e-26 Coronary artery disease; LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg16070018 chr6:26224392 HIST1H3E 0.59 7.45 0.37 7.55e-13 Gout;Renal underexcretion gout; LIHC trans rs4927850 1.000 rs7627868 chr3:195753473 A/T cg16724585 chr3:197361211 NA -0.46 -6.44 -0.33 4.17e-10 Pancreatic cancer; LIHC trans rs867371 1.000 rs7181655 chr15:82455616 T/C cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.37 -0.33 6.01e-10 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs9486719 1.000 rs12205728 chr6:96891838 T/C cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.84e-10 Diabetic kidney disease; LIHC cis rs7647973 0.922 rs57273516 chr3:49483074 A/G cg07636037 chr3:49044803 WDR6 0.51 6.5 0.33 2.9e-10 Menarche (age at onset); LIHC cis rs7756236 0.521 rs9394368 chr6:36630525 C/G cg00935119 chr6:36647544 CDKN1A 0.46 6.56 0.33 1.94e-10 QRS duration; LIHC cis rs1355223 0.583 rs2941044 chr11:34867444 A/C cg06937548 chr11:34938143 PDHX;APIP 0.41 5.84 0.3 1.19e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs4319547 0.695 rs6488958 chr12:122880704 A/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.35 -0.37 1.52e-12 Body mass index; LIHC cis rs7618501 0.966 rs7372966 chr3:49788969 T/C cg24110177 chr3:50126178 RBM5 0.42 6.49 0.33 3.1e-10 Intelligence (multi-trait analysis); LIHC cis rs10779751 0.770 rs11585553 chr1:11233814 G/A cg08854313 chr1:11322531 MTOR -0.73 -8.91 -0.43 3.1e-17 Body mass index; LIHC cis rs208520 0.526 rs9354370 chr6:66808209 C/T cg07460842 chr6:66804631 NA 1.0 19.33 0.72 8.35e-57 Exhaled nitric oxide output; LIHC cis rs2204008 0.606 rs1581358 chr12:38391582 G/T cg26384229 chr12:38710491 ALG10B 0.82 9.83 0.47 3.08e-20 Bladder cancer; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.41 0.8 6.42e-77 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11102324 chr15:49658865 C15orf33 0.41 6.09 0.31 3.11e-9 Pancreatic cancer; LIHC cis rs1552244 0.554 rs58020561 chr3:10054682 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.57 -0.38 3.57e-13 Alzheimer's disease; LIHC cis rs17270561 0.636 rs1165216 chr6:25797971 G/A cg17691542 chr6:26056736 HIST1H1C 0.43 5.9 0.3 8.51e-9 Iron status biomarkers; LIHC cis rs12611088 0.600 rs12978269 chr19:44004419 T/C cg13740135 chr19:44006432 PHLDB3 -0.43 -6.24 -0.32 1.28e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs7944584 0.632 rs11039159 chr11:47294021 G/T cg20307385 chr11:47447363 PSMC3 0.58 6.42 0.33 4.49e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs17253792 0.822 rs13379353 chr14:56050478 G/C cg01858014 chr14:56050164 KTN1 -0.76 -8.12 -0.4 8.74e-15 Putamen volume; LIHC cis rs7071206 0.947 rs716255 chr10:79419679 A/T cg07817648 chr10:79422355 NA -0.35 -7.15 -0.36 5.46e-12 Bone mineral density; LIHC cis rs1005277 0.579 rs1780116 chr10:38526621 C/T cg25427524 chr10:38739819 LOC399744 -0.72 -14.01 -0.6 1.41e-35 Extrinsic epigenetic age acceleration; LIHC cis rs2180341 1.000 rs6903878 chr6:127638600 C/G cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC trans rs6951245 0.529 rs76001997 chr7:1152615 C/T cg13565492 chr6:43139072 SRF -0.78 -7.26 -0.37 2.7e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2257205 0.667 rs6503872 chr17:56696008 C/T cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs1577917 1.000 rs10455455 chr6:86670214 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.8 -0.35 4.72e-11 Response to antipsychotic treatment; LIHC cis rs6448317 0.556 rs6814108 chr4:24904781 C/T cg21108841 chr4:24914750 CCDC149 0.52 6.39 0.33 5.45e-10 Heschl's gyrus morphology; LIHC cis rs2257205 0.667 rs8070007 chr17:56709169 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs3106136 0.872 rs10033662 chr4:95239462 G/A cg11021082 chr4:95130006 SMARCAD1 0.43 7.7 0.38 1.46e-13 Capecitabine sensitivity; LIHC trans rs4650994 1.000 rs10913568 chr1:178513411 C/T cg05059571 chr16:84539110 KIAA1609 -0.39 -6.53 -0.33 2.36e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2839186 0.732 rs8131458 chr21:47694712 G/A cg12516959 chr21:47718080 NA -0.38 -6.0 -0.31 4.93e-9 Testicular germ cell tumor; LIHC cis rs10779751 1.000 rs4845856 chr1:11274547 T/C cg08854313 chr1:11322531 MTOR 0.87 15.81 0.65 1.15e-42 Body mass index; LIHC cis rs6964587 0.869 rs2013334 chr7:91549657 G/A cg17063962 chr7:91808500 NA -0.98 -18.68 -0.71 3.49e-54 Breast cancer; LIHC cis rs68170813 0.559 rs76843318 chr7:106863173 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs1555322 0.530 rs2425043 chr20:33868702 T/C cg03689076 chr20:33865952 NA 0.57 6.7 0.34 8.63e-11 Attention deficit hyperactivity disorder; LIHC cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg13393036 chr8:95962371 TP53INP1 -0.44 -10.28 -0.49 8.82e-22 Type 2 diabetes; LIHC cis rs151997 0.538 rs62367392 chr5:50270298 T/C cg06027927 chr5:50259733 NA 0.54 6.41 0.33 4.87e-10 Callous-unemotional behaviour; LIHC cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg12463550 chr7:65579703 CRCP 0.67 6.86 0.35 3.29e-11 Diabetic kidney disease; LIHC trans rs9914544 0.966 rs7210746 chr17:18798593 T/C cg04702396 chr17:15466718 FAM18B2 0.44 6.65 0.34 1.18e-10 Educational attainment (years of education); LIHC cis rs6942756 0.806 rs2694572 chr7:128911721 A/G cg02491457 chr7:128862824 NA 0.6 9.57 0.46 2.3e-19 White matter hyperintensity burden; LIHC cis rs7100689 0.556 rs946893 chr10:82023524 A/G cg00277334 chr10:82204260 NA -0.51 -6.3 -0.32 9.21e-10 Post bronchodilator FEV1; LIHC cis rs5769765 0.773 rs9616395 chr22:50317803 A/G cg26441486 chr22:50317300 CRELD2 0.39 6.64 0.34 1.21e-10 Schizophrenia; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg17178900 chr1:205818956 PM20D1 0.67 10.06 0.48 5.03e-21 Menarche (age at onset); LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg26338869 chr17:61819248 STRADA 0.52 6.89 0.35 2.61e-11 Height; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg10360139 chr7:1886902 MAD1L1 -0.41 -6.28 -0.32 1.01e-9 Bipolar disorder and schizophrenia; LIHC trans rs1144333 0.655 rs76612182 chr1:76451889 C/T cg10154597 chr10:134910271 GPR123 0.31 6.11 0.31 2.72e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.44 -0.45 5.93e-19 Bipolar disorder; LIHC trans rs8002861 0.967 rs7984393 chr13:44484361 T/C cg17145862 chr1:211918768 LPGAT1 0.67 13.33 0.58 6e-33 Leprosy; LIHC cis rs7086627 0.515 rs10887894 chr10:82209952 A/G cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg13395646 chr4:1353034 KIAA1530 -0.63 -9.0 -0.44 1.55e-17 Obesity-related traits; LIHC cis rs7412746 0.634 rs4451553 chr1:150937329 C/T cg18016565 chr1:150552671 MCL1 0.52 9.7 0.46 8.02e-20 Melanoma; LIHC cis rs4319547 0.656 rs10161534 chr12:122873864 T/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.26 -0.37 2.68e-12 Body mass index; LIHC cis rs10540 0.908 rs35608427 chr11:498976 T/C cg03352830 chr11:487213 PTDSS2 0.83 6.98 0.35 1.55e-11 Body mass index; LIHC cis rs12887734 0.524 rs4906363 chr14:104210239 G/A cg08213375 chr14:104286397 PPP1R13B 0.51 8.75 0.43 1.02e-16 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs1461503 0.966 rs1461504 chr11:122845129 T/C cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs9388451 0.626 rs9385383 chr6:126086290 G/T cg05901451 chr6:126070800 HEY2 -0.66 -13.85 -0.6 6.4e-35 Brugada syndrome; LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.99 -0.31 5.41e-9 Menopause (age at onset); LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs12142240 0.698 rs7548675 chr1:46809321 C/G cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs59901009 1.000 rs59901009 chr11:10178437 T/C cg01453529 chr11:10209919 SBF2 -0.3 -5.89 -0.3 9.4e-9 Hematocrit;Hemoglobin concentration; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg05904041 chr7:4802774 FOXK1 0.61 6.29 0.32 9.48e-10 Mean platelet volume; LIHC cis rs6456156 0.586 rs720325 chr6:167467349 G/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.65 -0.42 2.09e-16 Primary biliary cholangitis; LIHC cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg21280719 chr6:42927975 GNMT -0.35 -7.53 -0.38 4.51e-13 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs903552 1.000 rs4965872 chr15:102004002 C/T cg00659931 chr15:102010125 PCSK6 -0.45 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg17971929 chr21:40555470 PSMG1 0.79 9.51 0.46 3.56e-19 Cognitive function; LIHC cis rs8062405 1.000 rs72793811 chr16:28839392 G/A cg00204512 chr16:28754710 NA 0.37 6.64 0.34 1.2e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs904251 0.525 rs12200378 chr6:37425304 A/G cg01843034 chr6:37503916 NA -0.37 -5.95 -0.31 6.61e-9 Cognitive performance; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg06853376 chr5:125937059 PHAX 0.42 6.64 0.34 1.24e-10 Calcium levels; LIHC trans rs61931739 0.517 rs4931771 chr12:34044557 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.82 0.35 4.04e-11 Morning vs. evening chronotype; LIHC cis rs2839186 0.872 rs13046834 chr21:47701485 T/C cg09417038 chr21:47716443 C21orf57 -0.5 -7.36 -0.37 1.35e-12 Testicular germ cell tumor; LIHC cis rs2439831 0.867 rs2255440 chr15:43830467 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 7.28 0.37 2.37e-12 Lung cancer in ever smokers; LIHC cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg05368731 chr17:41323189 NBR1 0.72 12.26 0.55 6.95e-29 Menopause (age at onset); LIHC trans rs11039798 0.588 rs7483361 chr11:48593786 G/A cg15704280 chr7:45808275 SEPT13 0.57 6.35 0.32 6.75e-10 Axial length; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26512142 chr11:2554198 KCNQ1 0.4 6.36 0.33 6.51e-10 Pancreatic cancer; LIHC cis rs8062405 1.000 rs2008514 chr16:28825605 A/G cg00204512 chr16:28754710 NA -0.36 -6.78 -0.34 5.34e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs597539 0.652 rs478647 chr11:68700424 C/T cg06028808 chr11:68637592 NA 0.44 5.81 0.3 1.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1577917 0.958 rs11756615 chr6:86679835 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.09 -0.48 3.82e-21 Response to antipsychotic treatment; LIHC cis rs904251 0.861 rs2776875 chr6:37486796 G/C cg08126542 chr6:37504118 NA -0.39 -6.15 -0.32 2.16e-9 Cognitive performance; LIHC cis rs3761847 0.593 rs1468673 chr9:123809890 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 5.96 0.31 6.2e-9 Rheumatoid arthritis; LIHC cis rs2274273 0.837 rs6573010 chr14:55721592 T/C cg01864836 chr14:55583639 NA -0.44 -8.26 -0.41 3.22e-15 Protein biomarker; LIHC trans rs783540 1.000 rs803688 chr15:83216793 A/G cg18393722 chr15:85113863 UBE2QP1 -0.43 -7.46 -0.37 6.98e-13 Schizophrenia; LIHC cis rs35110281 0.667 rs4819287 chr21:45120147 A/G cg21573476 chr21:45109991 RRP1B -0.57 -10.99 -0.51 2.9e-24 Mean corpuscular volume; LIHC cis rs7552404 0.765 rs211717 chr1:76106969 G/A cg22875332 chr1:76189707 ACADM -0.49 -7.3 -0.37 2.08e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg23835219 chr4:1244017 CTBP1;C4orf42 -0.4 -5.74 -0.3 2.14e-8 Longevity; LIHC cis rs875971 0.862 rs7798630 chr7:65771479 G/C cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs4407350 0.870 rs5765712 chr22:44914711 A/G cg11695653 chr22:44894386 LDOC1L -0.36 -6.2 -0.32 1.6e-9 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg00149659 chr3:10157352 C3orf10 0.64 6.91 0.35 2.31e-11 Alzheimer's disease; LIHC cis rs9596863 0.898 rs9568904 chr13:54330100 A/G ch.13.53330881F chr13:54432880 NA 0.44 6.04 0.31 4e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2842992 0.830 rs2758320 chr6:160070676 T/G cg11366901 chr6:160182831 ACAT2 0.94 14.88 0.63 5.99e-39 Age-related macular degeneration (geographic atrophy); LIHC cis rs2303745 0.589 rs10401700 chr19:17397700 A/C cg04248312 chr19:17393744 ANKLE1 -0.73 -12.33 -0.55 3.76e-29 Systemic lupus erythematosus; LIHC cis rs1348850 0.632 rs13008857 chr2:178514468 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.57 7.75 0.39 1.03e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1789 0.786 rs6414768 chr4:15695363 A/G cg16509355 chr4:15471240 CC2D2A -0.46 -6.92 -0.35 2.29e-11 Blood protein levels; LIHC trans rs3780486 0.846 rs7850878 chr9:33126570 A/G cg04842962 chr6:43655489 MRPS18A 1.07 25.66 0.81 1.04e-81 IgG glycosylation; LIHC cis rs1983891 0.874 rs1326322 chr6:41512462 G/T cg20194872 chr6:41519635 FOXP4 0.41 6.64 0.34 1.23e-10 Prostate cancer; LIHC cis rs6430585 0.528 rs6750549 chr2:136707480 A/G cg07305463 chr2:136567211 LCT -0.38 -5.88 -0.3 9.67e-9 Corneal structure; LIHC trans rs1005277 0.579 rs1780121 chr10:38529437 C/A cg27523141 chr10:43048294 ZNF37B 0.39 6.6 0.34 1.59e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9430161 0.579 rs11121669 chr1:11039567 T/C cg02454025 chr1:11042201 C1orf127 0.74 13.37 0.59 4.2e-33 Ewing sarcoma; LIHC cis rs600806 0.815 rs10745356 chr1:109960270 C/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.19 -0.36 4.04e-12 Intelligence (multi-trait analysis); LIHC cis rs6882046 0.513 rs35148765 chr5:88046158 C/A cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs10197940 0.638 rs2288193 chr2:152348842 T/A cg06191203 chr2:152266755 RIF1 -0.46 -7.7 -0.38 1.45e-13 Lung cancer; LIHC cis rs11122272 0.735 rs2808601 chr1:231536571 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.37 0.45 9.83e-19 Hemoglobin concentration; LIHC cis rs2153535 0.580 rs4960422 chr6:8459309 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC trans rs3780486 0.629 rs10971439 chr9:33180813 C/T cg04842962 chr6:43655489 MRPS18A -0.72 -10.36 -0.49 4.68e-22 IgG glycosylation; LIHC cis rs2120019 1.000 rs7162900 chr15:75368017 T/C cg06012730 chr15:75315579 PPCDC -0.32 -5.94 -0.31 7.02e-9 Blood trace element (Zn levels); LIHC cis rs72781680 0.821 rs72796361 chr2:24160689 A/T cg08917208 chr2:24149416 ATAD2B 0.65 6.57 0.33 1.86e-10 Lymphocyte counts; LIHC cis rs2304069 0.954 rs4705408 chr5:149412545 A/G cg12661370 chr5:149340060 SLC26A2 -0.5 -5.97 -0.31 5.81e-9 HIV-1 control; LIHC cis rs7264396 0.690 rs2425171 chr20:34443173 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.83 -0.51 1.07e-23 Total cholesterol levels; LIHC cis rs8017423 0.967 rs11159958 chr14:90716051 T/C cg04374321 chr14:90722782 PSMC1 0.74 14.44 0.62 2.96e-37 Mortality in heart failure; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg19687152 chr14:102968497 TECPR2 0.43 6.16 0.32 2.02e-9 Myopia (pathological); LIHC cis rs916888 0.697 rs199516 chr17:44856485 C/T cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs477895 1.000 rs34292685 chr11:64049021 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 8.29 0.41 2.58e-15 Mean platelet volume; LIHC cis rs2274273 0.624 rs8015211 chr14:55841447 A/G cg01864836 chr14:55583639 NA -0.35 -5.87 -0.3 1.03e-8 Protein biomarker; LIHC cis rs6542838 0.553 rs6739503 chr2:99537295 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.41 -6.67 -0.34 1.03e-10 Fear of minor pain; LIHC cis rs7208859 0.573 rs216443 chr17:28931871 A/G cg14067834 chr17:29058358 SUZ12P 0.6 6.21 0.32 1.5e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs933688 0.532 rs10072084 chr5:90539203 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.37 6.57 0.33 1.91e-10 Smoking behavior; LIHC cis rs9918079 0.560 rs4557256 chr4:15626647 A/C cg16509355 chr4:15471240 CC2D2A -0.46 -7.17 -0.36 4.71e-12 Obesity-related traits; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg19635926 chr16:89946313 TCF25 0.48 6.71 0.34 8.23e-11 Skin colour saturation; LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17662584 chr22:40440687 TNRC6B 0.44 6.21 0.32 1.53e-9 Pancreatic cancer; LIHC cis rs600806 0.850 rs115935180 chr1:109976775 C/G cg16275483 chr1:110013120 SYPL2 -0.48 -5.94 -0.31 6.99e-9 Intelligence (multi-trait analysis); LIHC cis rs9640161 0.789 rs2098053 chr7:150043205 G/A cg17279839 chr7:150038598 RARRES2 0.58 11.8 0.54 3.41e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg11764359 chr7:65958608 NA 0.57 5.82 0.3 1.39e-8 Diabetic kidney disease; LIHC cis rs6545883 0.894 rs2177962 chr2:61588070 T/A cg14146966 chr2:61757674 XPO1 -0.44 -7.29 -0.37 2.13e-12 Tuberculosis; LIHC cis rs8180040 0.620 rs9844122 chr3:47108330 C/T cg16586182 chr3:47516702 SCAP -0.49 -8.78 -0.43 7.8e-17 Colorectal cancer; LIHC cis rs8056893 0.714 rs1110570 chr16:68408119 G/C cg02226672 chr16:68398533 SMPD3 0.42 5.9 0.3 8.72e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs782590 0.643 rs13032503 chr2:55739093 C/T cg03859395 chr2:55845619 SMEK2 -0.49 -8.18 -0.4 5.71e-15 Metabolic syndrome; LIHC cis rs6963495 0.556 rs818481 chr7:105158467 G/C cg19920283 chr7:105172520 RINT1 0.47 5.96 0.31 6.26e-9 Bipolar disorder (body mass index interaction); LIHC cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg11644478 chr21:40555479 PSMG1 0.86 10.95 0.51 4.13e-24 Cognitive function; LIHC cis rs2836950 0.520 rs8133928 chr21:40689963 G/A cg06238570 chr21:40685208 BRWD1 -0.45 -7.42 -0.37 9.54e-13 Menarche (age at onset); LIHC cis rs1577917 1.000 rs12154056 chr6:86634094 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg17391518 chr19:59028285 ZBTB45 0.47 6.77 0.34 5.59e-11 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6840360 0.967 rs6832562 chr4:152602798 A/G cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.42e-10 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.807 rs12816136 chr12:38456037 A/G cg26384229 chr12:38710491 ALG10B -0.64 -9.18 -0.44 4.1e-18 Bladder cancer; LIHC cis rs4563143 0.514 rs55727361 chr19:29300415 A/T cg04546413 chr19:29218101 NA 0.5 8.58 0.42 3.41e-16 Methadone dose in opioid dependence; LIHC cis rs2637266 0.626 rs846603 chr10:78570793 A/G cg18941641 chr10:78392320 NA -0.3 -6.33 -0.32 7.57e-10 Pulmonary function; LIHC cis rs10504229 1.000 rs73591706 chr8:58195633 C/T cg02290350 chr8:58132656 NA 0.47 9.18 0.44 4.31e-18 Developmental language disorder (linguistic errors); LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg24693881 chr1:107596107 NA 0.56 9.71 0.46 7.52e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4819052 0.851 rs2838855 chr21:46680566 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.51 -7.39 -0.37 1.12e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.58 0.46 2.13e-19 Bipolar disorder; LIHC cis rs4927850 0.958 rs1975582 chr3:195751439 G/T cg01181863 chr3:195395398 SDHAP2 -0.52 -6.84 -0.35 3.62e-11 Pancreatic cancer; LIHC cis rs3008870 1.000 rs2815352 chr1:67482104 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 15.93 0.65 3.95e-43 Lymphocyte percentage of white cells; LIHC cis rs929354 0.742 rs7785227 chr7:156999297 C/T cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.88e-9 Body mass index; LIHC cis rs7662987 0.517 rs2602876 chr4:100039535 A/T cg12011299 chr4:100065546 ADH4 0.65 10.83 0.51 1.09e-23 Smoking initiation; LIHC cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg11890956 chr21:40555474 PSMG1 1.03 14.59 0.62 7.75e-38 Cognitive function; LIHC cis rs2073300 1.000 rs6114144 chr20:23462022 A/T cg12062639 chr20:23401060 NAPB 0.78 9.75 0.47 5.71e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11056748 chr11:66036038 RAB1B -0.54 -6.05 -0.31 3.73e-9 Systolic blood pressure; LIHC cis rs17826219 0.500 rs61685770 chr17:29085713 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 8.11e-15 Body mass index; LIHC cis rs7124681 0.505 rs7126378 chr11:47585348 G/T cg20307385 chr11:47447363 PSMC3 0.8 12.07 0.55 3.5e-28 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs763121 0.925 rs1056661 chr22:39080245 A/G cg14440974 chr22:39074834 NA -0.35 -6.04 -0.31 4.09e-9 Menopause (age at onset); LIHC cis rs9549367 0.737 rs11619691 chr13:113904636 T/C cg00898013 chr13:113819073 PROZ -0.42 -7.18 -0.36 4.24e-12 Platelet distribution width; LIHC cis rs7772486 0.719 rs702317 chr6:146005010 C/T cg13319975 chr6:146136371 FBXO30 0.4 6.45 0.33 3.78e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1005277 0.579 rs1985707 chr10:38434098 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2070433 0.615 rs2073379 chr21:47863025 C/T cg12379764 chr21:47803548 PCNT 0.73 10.45 0.49 2.21e-22 Lymphocyte counts; LIHC cis rs10751667 0.961 rs7396670 chr11:929269 A/G ch.11.42038R chr11:967971 AP2A2 0.57 10.49 0.49 1.7e-22 Alzheimer's disease (late onset); LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg07424592 chr7:64974309 NA -0.44 -6.72 -0.34 7.5e-11 Calcium levels; LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg24846343 chr22:24311635 DDTL -0.67 -12.34 -0.56 3.32e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs11148252 0.553 rs9536236 chr13:53255012 T/A cg18335740 chr13:41363409 SLC25A15 0.55 10.17 0.48 2.04e-21 Lewy body disease; LIHC cis rs2777491 0.957 rs7181911 chr15:41674060 T/C cg18705301 chr15:41695430 NDUFAF1 -0.59 -9.06 -0.44 1e-17 Ulcerative colitis; LIHC cis rs12142240 0.667 rs12062 chr1:46830447 G/T cg14993813 chr1:46806288 NSUN4 0.65 6.1 0.31 2.95e-9 Menopause (age at onset); LIHC cis rs2439831 0.867 rs496584 chr15:43831923 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.56 7.44 0.37 8.29e-13 Lung cancer in ever smokers; LIHC cis rs2380220 0.938 rs6923253 chr6:95970141 C/G cg04719120 chr6:96025338 MANEA 0.64 6.78 0.34 5.19e-11 Behavioural disinhibition (generation interaction); LIHC cis rs4746818 0.793 rs2008553 chr10:70860475 C/G cg11621586 chr10:70884670 VPS26A 0.65 9.37 0.45 1e-18 Left atrial antero-posterior diameter; LIHC cis rs6089584 1.000 rs3787424 chr20:60559219 G/A cg13770153 chr20:60521292 NA -0.36 -7.04 -0.36 1.03e-11 Body mass index; LIHC cis rs870825 0.860 rs56180712 chr4:185600223 A/G cg04058563 chr4:185651563 MLF1IP 0.84 7.01 0.35 1.31e-11 Blood protein levels; LIHC cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.38 5.73 0.3 2.24e-8 Schizophrenia; LIHC cis rs796364 1.000 rs281763 chr2:200794870 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.27 0.41 2.94e-15 Schizophrenia; LIHC cis rs57920188 0.584 rs12068729 chr1:4091650 A/G cg20703997 chr1:4087676 NA 0.49 6.08 0.31 3.22e-9 Interleukin-17 levels; LIHC cis rs2749592 0.725 rs9417245 chr10:37826322 C/T cg00409905 chr10:38381863 ZNF37A 0.42 6.4 0.33 5.14e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10464366 0.544 rs12668821 chr7:39167846 T/A cg10621924 chr7:39171070 POU6F2 0.42 6.51 0.33 2.67e-10 IgG glycosylation; LIHC trans rs62103177 0.759 rs9956512 chr18:77607517 G/A cg05926928 chr17:57297772 GDPD1 1.25 13.63 0.59 4.42e-34 Opioid sensitivity; LIHC cis rs7552404 1.000 rs4949876 chr1:76173377 C/T cg03433033 chr1:76189801 ACADM 0.67 9.47 0.46 4.64e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg07677032 chr17:61819896 STRADA 0.44 6.35 0.32 6.89e-10 Prudent dietary pattern; LIHC cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg24879335 chr3:133465180 TF 0.26 5.89 0.3 9.49e-9 Iron status biomarkers; LIHC cis rs1005277 0.579 rs1740737 chr10:38499365 G/T cg17219203 chr10:38645113 HSD17B7P2 -0.4 -5.83 -0.3 1.26e-8 Extrinsic epigenetic age acceleration; LIHC cis rs7914558 1.000 rs943038 chr10:104826261 T/C cg15744005 chr10:104629667 AS3MT -0.39 -8.86 -0.43 4.32e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2576037 0.583 rs545344 chr18:44367079 A/G cg19077165 chr18:44547161 KATNAL2 -0.47 -6.84 -0.35 3.73e-11 Personality dimensions; LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg03721293 chr16:90014378 DEF8 0.37 6.47 0.33 3.37e-10 Interleukin-17 levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19102404 chr1:116941269 C1orf203;ATP1A1 -0.36 -6.3 -0.32 9.36e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9649213 0.574 rs7794187 chr7:97889758 A/C cg08684580 chr7:98029266 BAIAP2L1 -0.42 -6.25 -0.32 1.19e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.98 -0.31 5.63e-9 Colorectal cancer; LIHC cis rs2281845 0.929 rs6704363 chr1:201096383 A/G cg24849736 chr1:201084428 NA -0.38 -7.41 -0.37 1.01e-12 Permanent tooth development; LIHC cis rs1800469 1.000 rs2241712 chr19:41869756 C/T cg09537434 chr19:41945824 ATP5SL -0.72 -10.09 -0.48 3.9e-21 Colorectal cancer; LIHC cis rs3749237 0.595 rs3924462 chr3:49524236 T/G cg06212747 chr3:49208901 KLHDC8B 0.46 6.01 0.31 4.66e-9 Resting heart rate; LIHC cis rs7091068 0.566 rs1326220 chr10:95486155 G/A cg20715218 chr10:95462985 C10orf4 0.58 6.18 0.32 1.86e-9 Urinary tract infection frequency; LIHC cis rs1023500 0.551 rs61665536 chr22:42512613 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.2 -0.32 1.67e-9 Schizophrenia; LIHC cis rs611744 0.647 rs2859813 chr8:109263497 G/A cg21045802 chr8:109455806 TTC35 0.59 10.46 0.49 2.08e-22 Dupuytren's disease; LIHC cis rs7659604 0.539 rs7660548 chr4:122730821 G/C cg20573242 chr4:122745356 CCNA2 0.53 7.69 0.38 1.58e-13 Type 2 diabetes; LIHC cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg03806693 chr22:41940476 POLR3H -1.14 -13.43 -0.59 2.64e-33 Vitiligo; LIHC cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg12292205 chr6:26970375 C6orf41 -0.48 -8.15 -0.4 6.74e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg13770153 chr20:60521292 NA -0.35 -7.06 -0.36 9.56e-12 Body mass index; LIHC cis rs77633900 0.614 rs113557153 chr15:76994445 A/G cg21673338 chr15:77095150 SCAPER -0.52 -7.17 -0.36 4.66e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs7208859 0.614 rs216412 chr17:28903394 A/G cg14067834 chr17:29058358 SUZ12P -0.59 -6.34 -0.32 7.33e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8063761 0.589 rs4238833 chr16:90050689 G/T cg12064134 chr16:90016061 DEF8 0.35 5.86 0.3 1.11e-8 Squamous cell carcinoma; LIHC trans rs561341 0.714 rs473535 chr17:30312365 A/G cg20587970 chr11:113659929 NA -1.32 -11.06 -0.51 1.68e-24 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg20607798 chr8:58055168 NA 0.5 6.16 0.32 2.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.882 rs13099136 chr3:10031431 G/A cg08888203 chr3:10149979 C3orf24 0.45 5.96 0.31 6.11e-9 Alzheimer's disease; LIHC cis rs2637266 0.935 rs2583055 chr10:78400029 C/T cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs9902453 0.845 rs3102559 chr17:28029723 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.81 0.54 3.07e-27 Coffee consumption (cups per day); LIHC cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.15 0.52 7.72e-25 Colorectal cancer; LIHC cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg18357526 chr6:26021779 HIST1H4A 0.81 11.32 0.52 1.89e-25 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.935 rs2149093 chr6:167373045 T/C cg23791538 chr6:167370224 RNASET2 0.59 9.4 0.45 8.27e-19 Crohn's disease; LIHC cis rs6582630 0.598 rs10880614 chr12:38509766 G/A cg26384229 chr12:38710491 ALG10B -0.49 -6.79 -0.34 4.84e-11 Drug-induced liver injury (flucloxacillin); LIHC trans rs78049276 0.688 rs56024659 chr4:148378604 C/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.62 -7.94 -0.39 2.94e-14 Pulse pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19787033 chr11:77850962 ALG8 0.45 6.26 0.32 1.13e-9 Pancreatic cancer; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.65 0.62 4.57e-38 Prudent dietary pattern; LIHC cis rs765787 0.530 rs11636440 chr15:45535982 C/T cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs2933343 0.700 rs2249514 chr3:128643812 C/T cg25356066 chr3:128598488 ACAD9 0.52 7.21 0.36 3.68e-12 IgG glycosylation; LIHC cis rs17854409 1.000 rs16983290 chr20:61478894 A/G cg06598544 chr20:61472147 COL9A3 0.8 7.97 0.4 2.46e-14 Obesity-related traits; LIHC cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg16497277 chr3:49208875 KLHDC8B -0.51 -6.38 -0.33 5.61e-10 Menarche (age at onset); LIHC cis rs2625529 0.627 rs11858015 chr15:72552492 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.73 -0.3 2.16e-8 Red blood cell count; LIHC cis rs3796352 1.000 rs11713206 chr3:52999243 A/G cg07884673 chr3:53033167 SFMBT1 0.99 6.93 0.35 2.11e-11 Immune reponse to smallpox (secreted IL-2); LIHC trans rs10915437 0.531 rs4233259 chr1:4197842 G/A cg23269655 chr10:75541687 CHCHD1 0.41 6.04 0.31 3.99e-9 Migraine - clinic-based; LIHC cis rs2274273 0.870 rs10134339 chr14:55814380 T/C cg04306507 chr14:55594613 LGALS3 0.32 6.08 0.31 3.13e-9 Protein biomarker; LIHC cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg18357526 chr6:26021779 HIST1H4A 0.9 12.45 0.56 1.36e-29 Intelligence (multi-trait analysis); LIHC cis rs9640161 0.711 rs3735170 chr7:150034184 T/C cg10018233 chr7:150070692 REPIN1 0.56 8.61 0.42 2.75e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs597539 0.652 rs613128 chr11:68638058 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.08e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24294857 chr1:20812821 CAMK2N1 0.4 6.12 0.31 2.53e-9 Lung function (FEV1/FVC); LIHC trans rs4824093 0.610 rs58888255 chr22:50315627 G/A cg09872104 chr7:134855509 C7orf49 -0.78 -6.18 -0.32 1.84e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs9596863 0.898 rs34617186 chr13:54370594 A/G ch.13.53330881F chr13:54432880 NA 0.43 5.79 0.3 1.63e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs116095464 0.558 rs57335027 chr5:262907 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs9517313 0.584 rs9556974 chr13:99216302 G/C cg20487152 chr13:99095054 FARP1 -0.39 -6.3 -0.32 9.4e-10 Neuroticism; LIHC cis rs7520050 0.966 rs7524495 chr1:46266932 T/C cg03146154 chr1:46216737 IPP -0.4 -6.55 -0.33 2.11e-10 Red blood cell count;Reticulocyte count; LIHC cis rs4243830 0.850 rs12744992 chr1:6601290 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.94 -11.68 -0.53 9.75e-27 Body mass index; LIHC trans rs13405020 0.578 rs1453290 chr2:138219404 T/C cg10008445 chr10:105630969 NA -0.37 -6.09 -0.31 2.99e-9 Non-small cell lung cancer; LIHC cis rs365132 0.875 rs187114 chr5:176364039 A/G cg16309518 chr5:176445507 NA -0.53 -9.84 -0.47 2.76e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs2274273 0.837 rs10131913 chr14:55787420 A/G cg01864836 chr14:55583639 NA -0.4 -7.45 -0.37 7.51e-13 Protein biomarker; LIHC cis rs1863824 0.625 rs10887600 chr10:88169072 C/T cg07322936 chr10:88137208 NA -0.47 -5.99 -0.31 5.43e-9 Schizophrenia; LIHC cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg00684032 chr4:1343700 KIAA1530 0.51 7.75 0.39 1.03e-13 Obesity-related traits; LIHC cis rs875971 0.965 rs9969301 chr7:65781655 G/A cg18876405 chr7:65276391 NA -0.37 -6.73 -0.34 7.2e-11 Aortic root size; LIHC cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg07092213 chr7:1199455 ZFAND2A -0.4 -5.94 -0.31 7.06e-9 Longevity;Endometriosis; LIHC cis rs3091242 0.934 rs686631 chr1:25719599 A/T cg09222892 chr1:25734099 RHCE -0.44 -8.1 -0.4 9.96e-15 Erythrocyte sedimentation rate; LIHC cis rs3008870 0.755 rs1925410 chr1:67365230 C/T cg02640540 chr1:67518911 SLC35D1 -0.48 -7.47 -0.37 6.83e-13 Lymphocyte percentage of white cells; LIHC cis rs7927771 0.524 rs6485763 chr11:47627302 C/T cg20307385 chr11:47447363 PSMC3 0.8 12.06 0.55 3.89e-28 Subjective well-being; LIHC cis rs651907 0.535 rs13094911 chr3:101519021 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs7131987 0.868 rs11050151 chr12:29403008 T/A cg21522988 chr12:29376872 FAR2 0.3 7.0 0.35 1.33e-11 QT interval; LIHC cis rs1865760 0.566 rs3752419 chr6:26027433 C/T cg18357526 chr6:26021779 HIST1H4A 0.44 6.37 0.33 6.04e-10 Height; LIHC cis rs6754311 0.731 rs2164210 chr2:136580287 T/C cg25344623 chr2:136566232 LCT 0.42 8.59 0.42 3.11e-16 Mosquito bite size; LIHC cis rs1707322 0.686 rs2230658 chr1:46078854 A/G cg03146154 chr1:46216737 IPP -0.57 -9.53 -0.46 3.09e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11583043 1.000 rs12567858 chr1:101517688 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.67 8.5 0.42 6.15e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7772486 0.743 rs9376955 chr6:145949404 T/A cg05347473 chr6:146136440 FBXO30 0.33 5.74 0.3 2.08e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs727505 1.000 rs10271646 chr7:124549573 T/C cg23710748 chr7:124431027 NA -0.32 -5.91 -0.3 8.38e-9 Lewy body disease; LIHC cis rs1577917 0.771 rs9362239 chr6:86429263 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 10.45 0.49 2.24e-22 Response to antipsychotic treatment; LIHC cis rs208520 0.690 rs7764570 chr6:66827600 G/C cg07460842 chr6:66804631 NA -0.76 -8.61 -0.42 2.67e-16 Exhaled nitric oxide output; LIHC cis rs10876993 0.890 rs1092472 chr12:58036688 G/T cg18357645 chr12:58087776 OS9 0.49 8.09 0.4 1.06e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs11718455 0.921 rs1404482 chr3:43997282 A/G cg08738300 chr3:44038990 NA 0.51 9.02 0.44 1.35e-17 Coronary artery disease; LIHC trans rs7246657 0.941 rs7256130 chr19:37933981 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg05025164 chr4:1340916 KIAA1530 0.79 12.8 0.57 6.35e-31 Longevity; LIHC cis rs17286411 0.671 rs8062477 chr16:71803974 A/G cg06353428 chr16:71660113 MARVELD3 -0.42 -6.18 -0.32 1.83e-9 Blood protein levels; LIHC cis rs11077998 0.967 rs7350963 chr17:80491067 G/A cg10255544 chr17:80519551 FOXK2 0.49 8.93 0.43 2.72e-17 Reticulocyte fraction of red cells; LIHC cis rs1552244 0.882 rs67762674 chr3:10014485 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.64 -9.37 -0.45 1.05e-18 Alzheimer's disease; LIHC cis rs6456156 0.846 rs7749827 chr6:167515624 C/T cg23791538 chr6:167370224 RNASET2 0.4 6.45 0.33 3.84e-10 Primary biliary cholangitis; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg25811766 chr13:21894605 NA 0.75 13.41 0.59 2.94e-33 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs3784262 0.669 rs4646595 chr15:58302341 C/T cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.72 -0.3 2.32e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs9910055 0.573 rs113184718 chr17:42206543 A/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.54 -9.81 -0.47 3.59e-20 Total body bone mineral density; LIHC cis rs10883723 0.773 rs2296578 chr10:104240974 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.58 0.56 4.5e-30 Allergic disease (asthma, hay fever or eczema); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12315590 chr3:128997497 C3orf37 0.42 6.63 0.34 1.3100000000000001e-10 Cognitive function; LIHC cis rs4319547 0.626 rs10744210 chr12:122931793 A/G cg23029597 chr12:123009494 RSRC2 -0.53 -7.35 -0.37 1.45e-12 Body mass index; LIHC cis rs61990749 0.500 rs8011337 chr14:78272626 T/G cg23188588 chr14:78226832 SNW1;C14orf178 0.6 9.82 0.47 3.28e-20 Fibroblast growth factor basic levels; LIHC cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs8017423 1.000 rs8011810 chr14:90685669 A/G cg04374321 chr14:90722782 PSMC1 0.73 14.04 0.6 1.08e-35 Mortality in heart failure; LIHC cis rs798554 0.757 rs1182176 chr7:2874601 A/G cg13628971 chr7:2884303 GNA12 0.53 7.38 0.37 1.25e-12 Height; LIHC cis rs3780378 0.840 rs10119004 chr9:5071049 C/T cg02405213 chr9:5042618 JAK2 -0.52 -9.21 -0.45 3.25e-18 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs16854884 0.657 rs6778627 chr3:143720869 G/T cg06585982 chr3:143692056 C3orf58 0.55 7.18 0.36 4.48e-12 Economic and political preferences (feminism/equality); LIHC cis rs10256972 0.706 rs12701969 chr7:1121849 A/G cg16145915 chr7:1198662 ZFAND2A -0.37 -9.47 -0.46 4.91e-19 Longevity;Endometriosis; LIHC cis rs12479064 0.694 rs11896520 chr2:99995517 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.59 -6.56 -0.33 2.05e-10 Chronic sinus infection; LIHC cis rs7408868 1.000 rs10410514 chr19:15277610 C/T cg14696996 chr19:15285081 NOTCH3 0.53 7.1 0.36 7.41e-12 Pulse pressure; LIHC cis rs7173389 0.530 rs6495062 chr15:73682691 T/C cg01796676 chr15:73680284 NA 0.53 8.69 0.43 1.56e-16 Resting heart rate; LIHC cis rs9583531 0.600 rs9555724 chr13:111354110 C/T cg24331049 chr13:111365604 ING1 -0.64 -10.91 -0.51 5.46e-24 Coronary artery disease; LIHC cis rs4819052 0.851 rs10470247 chr21:46659018 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.04e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs477895 0.938 rs28395875 chr11:64024048 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 7.79 0.39 8.01e-14 Mean platelet volume; LIHC cis rs3770081 1.000 rs56104203 chr2:86336256 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.89 -10.0 -0.48 8.11e-21 Facial emotion recognition (sad faces); LIHC cis rs1865721 1.000 rs11659761 chr18:73186974 A/G cg26385618 chr18:73139727 C18orf62 -0.26 -6.66 -0.34 1.08e-10 Intelligence; LIHC cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs67460515 0.563 rs34630898 chr3:160827038 A/G cg03342759 chr3:160939853 NMD3 -0.62 -9.08 -0.44 8.78e-18 Parkinson's disease; LIHC cis rs7296418 0.961 rs7957096 chr12:123544878 A/G cg00376283 chr12:123451042 ABCB9 0.74 13.42 0.59 2.82e-33 Platelet count; LIHC cis rs10878977 0.565 rs7295234 chr12:69811369 A/C cg17330252 chr12:69809627 NA 0.37 5.82 0.3 1.34e-8 Colorectal cancer; LIHC cis rs911119 0.913 rs12710327 chr20:23569689 C/T cg16589663 chr20:23618590 CST3 0.68 7.12 0.36 6.6e-12 Chronic kidney disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg22843129 chr8:669177 ERICH1 0.4 6.18 0.32 1.83e-9 Longevity; LIHC cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg06481639 chr22:41940642 POLR3H -0.69 -7.0 -0.35 1.39e-11 Vitiligo; LIHC cis rs79149102 0.579 rs7342601 chr15:75306795 G/T cg17294928 chr15:75287854 SCAMP5 0.47 6.27 0.32 1.1e-9 Lung cancer; LIHC cis rs3733606 0.538 rs11734099 chr4:6891435 G/A cg05012661 chr4:6891264 NA 0.39 6.22 0.32 1.46e-9 Platelet count; LIHC cis rs11098499 0.697 rs4373140 chr4:120307698 A/G cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs9326248 1.000 rs585849 chr11:117069061 A/G cg26566898 chr11:117069891 TAGLN 0.47 7.34 0.37 1.59e-12 Blood protein levels; LIHC cis rs769267 0.930 rs2099334 chr19:19578450 A/G cg03709012 chr19:19516395 GATAD2A 1.03 18.52 0.71 1.52e-53 Tonsillectomy; LIHC cis rs13040088 1.000 rs6090159 chr20:61531351 C/G cg23096297 chr20:61557774 DIDO1 0.81 10.85 0.51 8.82e-24 Menopause (age at onset); LIHC cis rs4144743 0.759 rs16969966 chr17:45318452 G/T cg18085866 chr17:45331354 ITGB3 -0.64 -7.76 -0.39 1.01e-13 Body mass index; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.97 -0.35 1.6e-11 Diastolic blood pressure; LIHC cis rs12497850 0.829 rs8926 chr3:49052785 T/A cg06212747 chr3:49208901 KLHDC8B 0.59 7.76 0.39 9.77e-14 Parkinson's disease; LIHC cis rs1865760 0.566 rs9366634 chr6:26072396 C/G cg17691542 chr6:26056736 HIST1H1C 0.43 6.29 0.32 9.83e-10 Height; LIHC cis rs10744422 1.000 rs936083 chr12:123338964 A/G cg07706471 chr12:123319906 HIP1R -0.63 -8.28 -0.41 2.88e-15 Schizophrenia; LIHC cis rs782590 0.935 rs6739513 chr2:55749902 G/A cg03859395 chr2:55845619 SMEK2 0.92 15.71 0.65 3.07e-42 Metabolic syndrome; LIHC cis rs2629540 0.889 rs10901815 chr10:126435598 G/A cg08799069 chr10:126477246 METTL10 -0.53 -8.59 -0.42 3.15e-16 Cocaine dependence; LIHC cis rs116095464 0.558 rs10060089 chr5:205565 G/A cg22857025 chr5:266934 NA -1.65 -16.58 -0.67 9.67e-46 Breast cancer; LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg24846343 chr22:24311635 DDTL -0.56 -9.77 -0.47 4.71e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1823913 0.927 rs35339956 chr2:192126394 C/T cg12404831 chr2:192114017 MYO1B 0.33 6.69 0.34 9.35e-11 Obesity-related traits; LIHC cis rs7572733 0.534 rs58374969 chr2:198764363 C/T cg03934865 chr2:198174659 NA 0.49 6.95 0.35 1.89e-11 Dermatomyositis; LIHC cis rs4689642 0.756 rs4689089 chr4:7225587 C/G cg21353189 chr4:7228343 SORCS2 0.38 6.46 0.33 3.51e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg19318889 chr4:1322082 MAEA 0.4 5.77 0.3 1.81e-8 Obesity-related traits; LIHC cis rs477895 0.713 rs882146 chr11:63976699 G/A cg18225595 chr11:63971243 STIP1 0.68 8.5 0.42 5.94e-16 Mean platelet volume; LIHC cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg00166722 chr3:10149974 C3orf24 0.53 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC cis rs7098414 0.530 rs10749572 chr10:82136664 G/T cg01528321 chr10:82214614 TSPAN14 0.41 6.07 0.31 3.43e-9 Post bronchodilator FEV1; LIHC cis rs3749237 0.576 rs3877784 chr3:49539417 C/T cg03060546 chr3:49711283 APEH 0.64 10.52 0.49 1.31e-22 Resting heart rate; LIHC cis rs7312774 0.618 rs28716736 chr12:107364410 A/G cg16260113 chr12:107380972 MTERFD3 0.86 11.16 0.52 7.22e-25 Severe influenza A (H1N1) infection; LIHC cis rs56804039 1.000 rs17616779 chr8:8382374 A/G cg08975724 chr8:8085496 FLJ10661 0.46 6.46 0.33 3.64e-10 Cervical cancer; LIHC cis rs5769765 0.908 rs138864 chr22:50204712 G/A cg02269571 chr22:50332266 NA -0.65 -8.73 -0.43 1.17e-16 Schizophrenia; LIHC cis rs7903847 0.642 rs2297667 chr10:99145492 A/T cg06359132 chr10:99160096 RRP12 -0.41 -6.41 -0.33 4.88e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -6.52 -0.33 2.55e-10 Bipolar disorder and schizophrenia; LIHC cis rs7572733 0.534 rs1436131 chr2:198731230 A/C cg03934865 chr2:198174659 NA 0.46 6.64 0.34 1.25e-10 Dermatomyositis; LIHC cis rs8062405 0.965 rs56040780 chr16:28861881 C/T cg07451762 chr16:28383216 NA 0.31 5.94 0.31 7.12e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg10295955 chr4:187884368 NA -0.95 -22.99 -0.78 2.31e-71 Lobe attachment (rater-scored or self-reported); LIHC cis rs9467773 1.000 rs6925703 chr6:26521589 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.86 0.6 5.82e-35 Intelligence (multi-trait analysis); LIHC cis rs7587476 0.906 rs17487827 chr2:215644335 C/G cg04004882 chr2:215674386 BARD1 0.48 5.9 0.3 8.57e-9 Neuroblastoma; LIHC trans rs11098499 0.866 rs12374244 chr4:120281972 A/T cg25214090 chr10:38739885 LOC399744 0.48 7.67 0.38 1.8e-13 Corneal astigmatism; LIHC cis rs483180 0.512 rs866321 chr1:120224469 T/C cg19096424 chr1:120255104 PHGDH 0.62 7.62 0.38 2.54e-13 Macular telangiectasia type 2; LIHC cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg20607798 chr8:58055168 NA 0.69 8.23 0.41 3.93e-15 Developmental language disorder (linguistic errors); LIHC cis rs7224685 0.539 rs2054039 chr17:4014538 C/A cg09597638 chr17:3907349 NA 0.61 10.74 0.5 2.17e-23 Type 2 diabetes; LIHC cis rs10870270 0.956 rs11146425 chr10:133734261 C/T cg08754478 chr10:133766260 PPP2R2D -0.56 -8.27 -0.41 3.08e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2576037 0.583 rs9304336 chr18:44461687 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.9 -0.3 8.6e-9 Personality dimensions; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg12463550 chr7:65579703 CRCP 0.67 7.02 0.35 1.23e-11 Diabetic kidney disease; LIHC cis rs16854884 0.657 rs35193361 chr3:143716420 A/G cg06585982 chr3:143692056 C3orf58 0.51 6.17 0.32 1.9e-9 Economic and political preferences (feminism/equality); LIHC trans rs12620999 0.941 rs4663240 chr2:238036632 G/T cg15676719 chr1:167598521 RCSD1 -0.37 -6.65 -0.34 1.18e-10 Systemic lupus erythematosus; LIHC cis rs1005277 0.579 rs2474563 chr10:38375938 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs1030877 0.960 rs3792049 chr2:105901908 A/C cg02079111 chr2:105885981 TGFBRAP1 -0.69 -12.41 -0.56 1.86e-29 Obesity-related traits; LIHC cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg14004847 chr7:1930337 MAD1L1 -0.43 -6.1 -0.31 2.92e-9 Bipolar disorder and schizophrenia; LIHC cis rs2228479 0.850 rs17226666 chr16:89835401 G/A cg06558623 chr16:89946397 TCF25 0.85 11.76 0.54 4.68e-27 Skin colour saturation; LIHC cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg18305652 chr10:134549665 INPP5A 0.48 7.81 0.39 6.99e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs826838 1.000 rs11168676 chr12:38977304 A/G cg13010199 chr12:38710504 ALG10B 0.55 6.74 0.34 6.57e-11 Heart rate; LIHC cis rs3749237 0.595 rs4855873 chr3:49459114 A/C cg03060546 chr3:49711283 APEH 0.6 10.07 0.48 4.76e-21 Resting heart rate; LIHC cis rs35306767 0.668 rs12356612 chr10:1055055 C/T cg20503657 chr10:835505 NA 0.8 7.82 0.39 6.44e-14 Eosinophil percentage of granulocytes; LIHC cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg19318889 chr4:1322082 MAEA 0.47 6.55 0.33 2.13e-10 Obesity-related traits; LIHC cis rs11229555 1.000 rs1938598 chr11:58413910 T/C cg15696309 chr11:58395628 NA -0.73 -9.04 -0.44 1.23e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.23 0.81 4.46e-80 Prudent dietary pattern; LIHC cis rs709400 0.663 rs11624367 chr14:103892818 T/A cg26031613 chr14:104095156 KLC1 0.79 10.34 0.49 5.46e-22 Body mass index; LIHC cis rs8180040 0.966 rs6792488 chr3:47503349 C/T cg16586182 chr3:47516702 SCAP 0.61 11.95 0.54 9.64e-28 Colorectal cancer; LIHC cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.89 0.57 2.95e-31 Alzheimer's disease; LIHC cis rs10751667 0.666 rs10794354 chr11:954615 A/T cg06064525 chr11:970664 AP2A2 -0.56 -15.03 -0.63 1.52e-39 Alzheimer's disease (late onset); LIHC cis rs2070488 0.804 rs6764551 chr3:38460305 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.5 0.56 8.65e-30 Electrocardiographic conduction measures; LIHC trans rs916888 0.773 rs199534 chr17:44824213 T/G cg22968622 chr17:43663579 NA 1.17 12.95 0.57 1.73e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs17685 0.753 rs4398845 chr7:75716781 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.15 -0.32 2.13e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs3780486 0.801 rs6476398 chr9:33119241 C/T cg04842962 chr6:43655489 MRPS18A 1.08 24.35 0.8 1.1e-76 IgG glycosylation; LIHC cis rs1816752 0.713 rs7336357 chr13:25017590 T/C cg22771759 chr13:24902376 NA 0.31 6.47 0.33 3.49e-10 Obesity-related traits; LIHC trans rs1005277 0.522 rs1208681 chr10:38092975 C/T cg23533926 chr12:111358616 MYL2 -0.32 -6.23 -0.32 1.39e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12744310 0.887 rs12724625 chr1:41782270 G/C cg03962019 chr1:41807865 NA 0.39 6.23 0.32 1.38e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs801193 0.548 rs6975044 chr7:66227482 C/T cg11764359 chr7:65958608 NA 0.74 12.32 0.55 4.17e-29 Aortic root size; LIHC cis rs13161895 0.887 rs863231 chr5:179409613 C/T cg06664874 chr5:179499304 RNF130 0.49 6.35 0.32 6.84e-10 LDL cholesterol; LIHC cis rs908922 0.676 rs11581947 chr1:152482587 G/A cg20991723 chr1:152506922 NA 0.54 9.36 0.45 1.12e-18 Hair morphology; LIHC cis rs9902453 0.933 rs7221154 chr17:28505024 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.58 -8.95 -0.44 2.37e-17 Coffee consumption (cups per day); LIHC cis rs858239 0.730 rs858290 chr7:23248036 A/G cg18081818 chr7:23246105 NA -0.46 -7.08 -0.36 8.25e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs8180040 0.903 rs6791842 chr3:47279810 T/C cg27129171 chr3:47204927 SETD2 0.69 12.04 0.55 4.33e-28 Colorectal cancer; LIHC cis rs12744310 0.887 rs35807669 chr1:41801652 C/T cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs7249142 0.549 rs2283623 chr19:19283027 G/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.44 -7.26 -0.37 2.63e-12 IgG glycosylation; LIHC cis rs1670533 1.000 rs4690213 chr4:1054868 C/T cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.38e-17 Recombination rate (females); LIHC cis rs6459804 0.967 rs4289696 chr7:157508399 C/T cg05731713 chr7:157510257 PTPRN2 0.23 6.33 0.32 7.68e-10 Bipolar disorder and schizophrenia; LIHC cis rs10871290 0.881 rs4099290 chr16:74468889 A/G cg01733217 chr16:74700730 RFWD3 -0.42 -7.07 -0.36 8.8e-12 Breast cancer; LIHC cis rs7737355 0.947 rs4705894 chr5:131079288 A/G cg06307176 chr5:131281290 NA 0.4 5.84 0.3 1.19e-8 Life satisfaction; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg02290350 chr8:58132656 NA 0.5 10.4 0.49 3.31e-22 Developmental language disorder (linguistic errors); LIHC cis rs35883536 1.000 rs12409831 chr1:101107670 A/T cg14515779 chr1:101123966 NA -0.67 -13.22 -0.58 1.65e-32 Monocyte count; LIHC cis rs6912958 0.582 rs242285 chr6:88070743 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.24 0.52 3.71e-25 Monocyte percentage of white cells; LIHC cis rs11792861 0.591 rs2275641 chr9:111696389 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.69 11.39 0.52 1.05e-25 Menarche (age at onset); LIHC cis rs1348850 0.574 rs4893834 chr2:178442288 C/T cg27490568 chr2:178487706 NA -0.94 -10.98 -0.51 3.04e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9399135 0.967 rs12527683 chr6:135324534 C/T cg24558204 chr6:135376177 HBS1L 0.41 6.71 0.34 8.1e-11 Red blood cell count; LIHC cis rs4332037 0.510 rs11764040 chr7:1884830 G/C cg23422044 chr7:1970798 MAD1L1 -0.54 -8.95 -0.44 2.24e-17 Bipolar disorder; LIHC trans rs116095464 0.558 rs1971229 chr5:268187 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.15 0.36 5.43e-12 Breast cancer; LIHC cis rs9486719 0.895 rs3734238 chr6:96996228 A/T cg06623918 chr6:96969491 KIAA0776 -0.72 -7.23 -0.36 3.08e-12 Migraine;Coronary artery disease; LIHC cis rs244293 0.965 rs244352 chr17:53195478 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.51 7.52 0.38 4.77e-13 Menarche (age at onset); LIHC cis rs1559088 0.948 rs3760893 chr19:33597930 C/A cg27124370 chr19:33622961 WDR88 0.52 8.21 0.41 4.63e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg23758822 chr17:41437982 NA 0.92 17.07 0.68 1.09e-47 Menopause (age at onset); LIHC cis rs4969178 0.965 rs8071884 chr17:76398058 C/G cg20026190 chr17:76395443 PGS1 0.45 7.04 0.36 1.09e-11 HDL cholesterol levels; LIHC cis rs11711311 0.955 rs9851812 chr3:113412362 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.41 7.64 0.38 2.14e-13 IgG glycosylation; LIHC cis rs11212737 0.765 rs2624146 chr11:108520716 G/C cg22776369 chr11:108536276 DDX10 0.38 6.32 0.32 8.28e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs986417 1.000 rs8004736 chr14:61053061 T/C cg27398547 chr14:60952738 C14orf39 0.67 6.61 0.34 1.46e-10 Gut microbiota (bacterial taxa); LIHC cis rs919433 0.617 rs4850809 chr2:198583403 C/T cg00792783 chr2:198669748 PLCL1 -0.44 -6.39 -0.33 5.42e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs68170813 0.559 rs9641378 chr7:106868003 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.93 -0.31 7.49e-9 Coronary artery disease; LIHC cis rs10744422 0.800 rs6489240 chr12:123275030 T/C cg25930673 chr12:123319894 HIP1R -0.83 -10.27 -0.49 9.91e-22 Schizophrenia; LIHC cis rs2243480 1.000 rs1267820 chr7:66050295 C/G cg05590025 chr7:65112418 INTS4L2 -0.53 -5.75 -0.3 2.01e-8 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg18306943 chr3:40428807 ENTPD3 0.37 6.47 0.33 3.44e-10 Renal cell carcinoma; LIHC cis rs644799 0.526 rs506180 chr11:95623109 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.57 7.85 0.39 5.35e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1801251 1.000 rs11676216 chr2:233706368 C/T cg08000102 chr2:233561755 GIGYF2 -0.76 -11.51 -0.53 3.76e-26 Coronary artery disease; LIHC cis rs116095464 0.558 rs28418643 chr5:240859 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.71 -0.5 2.89e-23 Breast cancer; LIHC cis rs7395581 0.959 rs2167079 chr11:47270255 C/T cg25783544 chr11:47291846 MADD 0.43 6.34 0.32 7.42e-10 HDL cholesterol; LIHC cis rs10838687 0.736 rs11039144 chr11:47264044 G/A cg25783544 chr11:47291846 MADD 0.46 5.78 0.3 1.64e-8 Proinsulin levels; LIHC cis rs9457247 0.646 rs239934 chr6:167412048 G/A cg12798992 chr6:167411361 FGFR1OP 0.53 8.29 0.41 2.58e-15 Crohn's disease; LIHC trans rs801193 0.967 rs3800823 chr7:66147110 C/A cg26939375 chr7:64535504 NA -0.4 -6.27 -0.32 1.08e-9 Aortic root size; LIHC cis rs2573652 0.722 rs12903458 chr15:100542673 T/G cg09918751 chr15:100517450 ADAMTS17 -0.71 -12.63 -0.56 2.79e-30 Height; LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg07234388 chr1:156261841 TMEM79 0.51 9.21 0.45 3.42e-18 Tonsillectomy; LIHC cis rs4319547 0.661 rs10846830 chr12:122897220 C/G cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.35 -0.37 1.47e-12 Body mass index; LIHC cis rs651907 0.557 rs13099674 chr3:101489629 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.44 -0.33 4.09e-10 Colorectal cancer; LIHC cis rs8017423 0.935 rs17188598 chr14:90722473 A/T cg04374321 chr14:90722782 PSMC1 0.76 15.25 0.64 1.91e-40 Mortality in heart failure; LIHC trans rs2727020 0.729 rs10839283 chr11:49490943 T/C cg15704280 chr7:45808275 SEPT13 0.84 14.14 0.61 4.57e-36 Coronary artery disease; LIHC cis rs875971 0.862 rs11760844 chr7:65739883 C/G cg18876405 chr7:65276391 NA -0.35 -6.37 -0.33 6.12e-10 Aortic root size; LIHC cis rs9921222 0.585 rs7195617 chr16:376781 A/G cg26913058 chr16:419975 MRPL28 0.5 7.76 0.39 9.8e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs35110281 0.501 rs162378 chr21:44925905 A/G cg04455712 chr21:45112962 RRP1B -0.41 -6.76 -0.34 5.8200000000000003e-11 Mean corpuscular volume; LIHC cis rs1707322 0.716 rs10890342 chr1:46157087 C/T cg03146154 chr1:46216737 IPP 0.58 9.58 0.46 2.05e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7618501 0.633 rs2008877 chr3:50162291 T/G cg24110177 chr3:50126178 RBM5 0.51 8.22 0.41 4.13e-15 Intelligence (multi-trait analysis); LIHC cis rs611744 0.647 rs2859813 chr8:109263497 G/A cg18478394 chr8:109455254 TTC35 0.41 7.1 0.36 7.08e-12 Dupuytren's disease; LIHC cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg03517284 chr6:25882590 NA -0.6 -7.41 -0.37 1.01e-12 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.79 0.39 8.37e-14 Prudent dietary pattern; LIHC cis rs1008375 1.000 rs1006722 chr4:17618713 A/G cg15017067 chr4:17643749 FAM184B -0.33 -5.84 -0.3 1.23e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4242434 0.927 rs3736147 chr8:22471824 A/G cg03733263 chr8:22462867 KIAA1967 -0.84 -15.35 -0.64 7.87e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs3772130 0.564 rs28620947 chr3:121585631 G/A cg20356878 chr3:121714668 ILDR1 0.36 6.16 0.32 2.09e-9 Cognitive performance; LIHC cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg19318889 chr4:1322082 MAEA 0.47 7.4 0.37 1.07e-12 Longevity; LIHC cis rs526821 0.595 rs504661 chr11:55312683 A/G cg04317927 chr11:55418816 OR4S2 0.47 9.04 0.44 1.17e-17 Pediatric bone mineral density (spine); LIHC cis rs1198430 0.683 rs7551124 chr1:23785760 C/T cg19827787 chr1:23763612 ASAP3 0.31 6.68 0.34 9.89e-11 Total cholesterol levels; LIHC cis rs763121 1.000 rs138457 chr22:38898051 T/C cg06022373 chr22:39101656 GTPBP1 -0.59 -10.95 -0.51 4.18e-24 Menopause (age at onset); LIHC cis rs6977660 0.714 rs10486365 chr7:19801364 A/G cg07541023 chr7:19748670 TWISTNB 0.45 6.92 0.35 2.2e-11 Thyroid stimulating hormone; LIHC cis rs7216064 0.532 rs8065296 chr17:66018562 T/A cg12091567 chr17:66097778 LOC651250 0.84 14.14 0.61 4.52e-36 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs1030268 0.546 rs12707100 chr7:133274376 T/C cg10665199 chr7:133106180 EXOC4 0.5 5.98 0.31 5.53e-9 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 6.02e-12 Diabetic kidney disease; LIHC cis rs10744422 0.925 rs2880678 chr12:123317099 C/T cg18912006 chr12:123335444 HIP1R -0.56 -6.69 -0.34 8.9e-11 Schizophrenia; LIHC cis rs1256061 0.646 rs1256059 chr14:64710417 A/G cg23250157 chr14:64679961 SYNE2 0.43 6.35 0.32 6.72e-10 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.07e-8 Electroencephalogram traits; LIHC cis rs2806561 0.765 rs668234 chr1:23515467 G/A cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.45e-11 Height; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg09623986 chr2:74753896 AUP1;DQX1 0.44 6.67 0.34 1.03e-10 Alopecia areata; LIHC trans rs7668874 0.779 rs9784432 chr4:116742879 A/C cg08917878 chr5:172668965 NA -0.3 -6.05 -0.31 3.89e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs9902453 0.935 rs4310926 chr17:28433275 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 11.02 0.51 2.26e-24 Coffee consumption (cups per day); LIHC cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.82 8.08 0.4 1.1e-14 Platelet count; LIHC cis rs25645 0.744 rs66826786 chr17:38206092 T/C cg17467752 chr17:38218738 THRA -0.55 -9.24 -0.45 2.75e-18 Myeloid white cell count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18615184 chr17:61678500 TACO1 0.5 7.14 0.36 5.74e-12 Lung function (FEV1/FVC); LIHC cis rs11792861 0.926 rs17729523 chr9:111773317 T/C cg05043794 chr9:111880884 C9orf5 -0.3 -6.88 -0.35 2.88e-11 Menarche (age at onset); LIHC cis rs9399135 0.967 rs4895439 chr6:135318854 A/T cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.02e-11 Red blood cell count; LIHC cis rs10489202 0.632 rs202268 chr1:167927339 T/C cg24449463 chr1:168025552 DCAF6 -0.62 -9.69 -0.46 9.19e-20 Schizophrenia; LIHC cis rs12602486 1.000 rs76913347 chr17:42267048 C/T cg13607699 chr17:42295918 UBTF -0.76 -6.42 -0.33 4.65e-10 Glycated hemoglobin levels; LIHC cis rs7666738 0.546 rs1813970 chr4:98887167 A/G cg05340658 chr4:99064831 C4orf37 -0.53 -6.87 -0.35 3.13e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg18305652 chr10:134549665 INPP5A 0.44 6.46 0.33 3.67e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg20607798 chr8:58055168 NA 0.49 6.3 0.32 9.41e-10 Developmental language disorder (linguistic errors); LIHC cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg16325326 chr1:53192061 ZYG11B -0.5 -8.78 -0.43 8.15e-17 Monocyte count; LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg08219700 chr8:58056026 NA -0.5 -6.84 -0.35 3.72e-11 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.959 rs10166005 chr2:172607294 C/T cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.97 -0.7 2.53e-51 Schizophrenia; LIHC cis rs9359856 0.673 rs1179901 chr6:90321196 C/T cg13799429 chr6:90582589 CASP8AP2 -0.63 -6.78 -0.34 5.27e-11 Bipolar disorder; LIHC cis rs6429082 0.715 rs2131923 chr1:235580821 A/G cg26050004 chr1:235667680 B3GALNT2 -0.49 -7.42 -0.37 9.23e-13 Adiposity; LIHC cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6121246 0.529 rs750144 chr20:30179027 C/T cg13852791 chr20:30311386 BCL2L1 -0.71 -6.43 -0.33 4.3e-10 Mean corpuscular hemoglobin; LIHC cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg07092213 chr7:1199455 ZFAND2A -0.4 -6.12 -0.31 2.5e-9 Longevity;Endometriosis; LIHC cis rs35110281 0.666 rs2236665 chr21:45108987 C/A cg01579765 chr21:45077557 HSF2BP -0.32 -5.82 -0.3 1.33e-8 Mean corpuscular volume; LIHC cis rs473651 0.935 rs10170056 chr2:239339291 G/C cg18131467 chr2:239335373 ASB1 0.79 12.23 0.55 9.12e-29 Multiple system atrophy; LIHC cis rs1005277 0.579 rs2472173 chr10:38374638 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs9911578 0.835 rs10853006 chr17:56489076 G/A cg05425664 chr17:57184151 TRIM37 0.56 8.23 0.41 4.1e-15 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg16405210 chr4:1374714 KIAA1530 -0.41 -6.03 -0.31 4.36e-9 Obesity-related traits; LIHC cis rs9378688 0.654 rs12191002 chr6:2362070 A/G cg12303981 chr6:2244766 GMDS 0.45 6.28 0.32 1.05e-9 Caudate nucleus volume; LIHC cis rs11971779 0.616 rs10278377 chr7:139103071 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs875971 0.508 rs6947808 chr7:66045082 A/G cg14393609 chr7:65229607 NA -0.36 -5.86 -0.3 1.09e-8 Aortic root size; LIHC cis rs6752107 0.846 rs7559194 chr2:234206799 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.51 7.6 0.38 2.88e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7100689 0.577 rs1417219 chr10:82041409 C/T cg01528321 chr10:82214614 TSPAN14 0.87 11.76 0.54 4.85e-27 Post bronchodilator FEV1; LIHC trans rs6934970 1.000 rs12190989 chr6:113093127 C/T cg09308777 chr6:169852575 NA 0.62 6.16 0.32 2.08e-9 Bipolar disorder (body mass index interaction); LIHC cis rs1707322 1.000 rs7553924 chr1:46352624 T/C cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.78e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8078723 1.000 rs709592 chr17:38175553 C/T cg17467752 chr17:38218738 THRA 0.75 13.68 0.59 2.85e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs12971120 0.947 rs8083001 chr18:72165058 A/G cg26446133 chr18:72167187 CNDP2 -0.76 -15.54 -0.64 1.45e-41 Refractive error; LIHC cis rs9916302 0.904 rs755500 chr17:37409865 C/T cg00129232 chr17:37814104 STARD3 -0.39 -6.3 -0.32 9.2e-10 Glomerular filtration rate (creatinine); LIHC cis rs1816752 0.870 rs3825449 chr13:25014441 A/C cg22771759 chr13:24902376 NA 0.32 6.76 0.34 5.8e-11 Obesity-related traits; LIHC cis rs62179067 0.708 rs17363057 chr2:179936172 A/C cg27622325 chr2:179545785 TTN 0.66 5.75 0.3 1.95e-8 Late-onset Alzheimer's disease; LIHC cis rs6424115 0.830 rs2502999 chr1:24198321 A/G cg04160030 chr1:24195659 FUCA1 -0.36 -5.88 -0.3 9.82e-9 Immature fraction of reticulocytes; LIHC cis rs9309473 0.950 rs13391258 chr2:73848933 C/T cg20560298 chr2:73613845 ALMS1 -0.53 -6.65 -0.34 1.13e-10 Metabolite levels; LIHC cis rs2576037 0.526 rs10853545 chr18:44475220 A/T cg19077165 chr18:44547161 KATNAL2 -0.45 -6.9 -0.35 2.55e-11 Personality dimensions; LIHC cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg13152130 chr6:118910203 C6orf204 -0.62 -6.59 -0.34 1.63e-10 Diastolic blood pressure; LIHC cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg17971929 chr21:40555470 PSMG1 0.51 7.76 0.39 1e-13 Cognitive function; LIHC cis rs10131894 0.611 rs175001 chr14:75436452 A/C cg08847533 chr14:75593920 NEK9 0.86 16.22 0.66 2.69e-44 Coronary artery disease; LIHC cis rs2303745 0.589 rs1864116 chr19:17393015 C/T cg02221750 chr19:17393354 ANKLE1 -0.41 -5.9 -0.3 8.53e-9 Systemic lupus erythematosus; LIHC cis rs1790761 0.632 rs625978 chr11:67344664 C/T cg01069141 chr11:67398826 TBX10;NUDT8 0.38 6.7 0.34 8.77e-11 Mean corpuscular volume; LIHC cis rs12220238 1.000 rs10824098 chr10:75943579 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.86 0.35 3.21e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs4908768 0.501 rs6677736 chr1:8552804 A/T cg20416874 chr1:8611966 RERE -0.68 -14.36 -0.61 6.45e-37 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs35306767 0.633 rs17221491 chr10:1065191 A/G cg26597838 chr10:835615 NA 0.8 7.53 0.38 4.68e-13 Eosinophil percentage of granulocytes; LIHC cis rs7534824 0.582 rs61780297 chr1:101400855 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.41 0.37 1.02e-12 Refractive astigmatism; LIHC cis rs7216064 0.532 rs3890640 chr17:66053028 C/T cg12091567 chr17:66097778 LOC651250 0.86 14.45 0.62 2.9e-37 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6762 0.748 rs28636471 chr11:840639 T/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.81 -9.74 -0.47 5.84e-20 Mean platelet volume; LIHC cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg25894440 chr7:65020034 NA -0.54 -6.27 -0.32 1.08e-9 Diabetic kidney disease; LIHC cis rs1580019 0.587 rs1597555 chr7:32546118 T/G cg06627557 chr7:32535165 LSM5;AVL9 1.14 26.47 0.82 8.62e-85 Cognitive ability; LIHC cis rs12586317 0.547 rs60152856 chr14:35421373 G/A cg16230307 chr14:35515116 FAM177A1 0.77 12.35 0.56 3.23e-29 Psoriasis; LIHC cis rs3768617 0.510 rs2027076 chr1:183073407 C/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.91 0.51 5.56e-24 Fuchs's corneal dystrophy; LIHC cis rs12142240 0.698 rs1053628 chr1:46827769 C/T cg00530320 chr1:46809349 NSUN4 0.53 5.74 0.3 2.12e-8 Menopause (age at onset); LIHC cis rs3106136 0.546 rs2276910 chr4:95129238 T/C cg11021082 chr4:95130006 SMARCAD1 -0.52 -9.77 -0.47 4.93e-20 Capecitabine sensitivity; LIHC cis rs7089973 0.668 rs7898347 chr10:116644324 G/A cg23260525 chr10:116636907 FAM160B1 0.38 7.23 0.36 3.17e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9394841 0.667 rs3747749 chr6:41770604 G/A cg17623882 chr6:41773611 USP49 -0.44 -5.87 -0.3 1.04e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs2180341 0.883 rs7760748 chr6:127690062 C/T cg24812749 chr6:127587940 RNF146 1.03 15.33 0.64 9.68e-41 Breast cancer; LIHC cis rs1144333 0.655 rs76992868 chr1:76418916 G/A cg03433033 chr1:76189801 ACADM 0.53 7.56 0.38 3.79e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs4319547 0.656 rs6488951 chr12:122873928 A/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.19 -0.36 3.98e-12 Body mass index; LIHC cis rs11997175 0.646 rs4733177 chr8:33691754 A/G ch.8.33884649F chr8:33765107 NA 0.31 5.72 0.3 2.34e-8 Body mass index; LIHC cis rs6430585 0.528 rs16832205 chr2:136684632 G/A cg25344623 chr2:136566232 LCT -0.38 -6.1 -0.31 2.88e-9 Corneal structure; LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg08280861 chr8:58055591 NA 0.49 6.14 0.31 2.35e-9 Developmental language disorder (linguistic errors); LIHC cis rs796364 0.806 rs77853713 chr2:201006880 A/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs9611565 0.559 rs12483860 chr22:41961916 C/T cg06634786 chr22:41940651 POLR3H -0.61 -6.53 -0.33 2.39e-10 Vitiligo; LIHC trans rs867371 1.000 rs8041868 chr15:82472326 C/T cg18393722 chr15:85113863 UBE2QP1 -0.41 -6.95 -0.35 1.91e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7552404 1.000 rs1498316 chr1:76159198 G/A cg10523679 chr1:76189770 ACADM 0.64 8.63 0.42 2.37e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg12386194 chr3:101231763 SENP7 0.47 6.85 0.35 3.37e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs7937682 0.889 rs1789361 chr11:111485334 T/C cg09085632 chr11:111637200 PPP2R1B -0.92 -11.06 -0.51 1.66e-24 Primary sclerosing cholangitis; LIHC cis rs1144333 0.655 rs75578876 chr1:76395586 A/C cg22875332 chr1:76189707 ACADM 0.42 6.29 0.32 9.69e-10 Attention function in attention deficit hyperactive disorder; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg18866267 chr4:3310044 NA 0.36 6.07 0.31 3.33e-9 Oropharynx cancer; LIHC cis rs769267 0.931 rs2965193 chr19:19454828 G/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.3 -0.32 9.19e-10 Tonsillectomy; LIHC cis rs769267 0.896 rs11882123 chr19:19386339 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC cis rs4808199 0.948 rs757000 chr19:19448301 A/G cg03709012 chr19:19516395 GATAD2A 0.99 15.84 0.65 9.42e-43 Nonalcoholic fatty liver disease; LIHC cis rs75908454 1.000 rs77344335 chr6:169948501 G/A cg19338460 chr6:170058176 WDR27 -0.8 -7.48 -0.37 6.42e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC cis rs12744310 1.000 rs12722758 chr1:41757015 G/A cg03962019 chr1:41807865 NA 0.38 6.1 0.31 2.82e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9611565 0.592 rs57102627 chr22:41987627 T/C cg06634786 chr22:41940651 POLR3H -0.56 -5.92 -0.3 7.82e-9 Vitiligo; LIHC cis rs6424115 0.708 rs12748109 chr1:24181177 C/T cg08896387 chr1:24191740 FUCA1 0.38 6.05 0.31 3.89e-9 Immature fraction of reticulocytes; LIHC cis rs35883536 0.647 rs2783702 chr1:101040836 G/A cg14515779 chr1:101123966 NA -0.45 -6.38 -0.33 5.67e-10 Monocyte count; LIHC cis rs2762353 0.603 rs12201071 chr6:25778055 C/T cg03264133 chr6:25882463 NA 0.48 6.38 0.33 5.84e-10 Blood metabolite levels; LIHC cis rs11098499 0.604 rs10022185 chr4:120571765 C/G cg09307838 chr4:120376055 NA 0.65 9.53 0.46 2.92e-19 Corneal astigmatism; LIHC cis rs8010715 0.816 rs8015168 chr14:24599872 A/T cg23112188 chr14:24563095 PCK2 -0.29 -6.08 -0.31 3.25e-9 IgG glycosylation; LIHC cis rs7903847 0.642 rs11817875 chr10:99158414 G/A cg20016023 chr10:99160130 RRP12 -0.43 -6.58 -0.34 1.73e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9814567 0.752 rs7649910 chr3:134241310 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs924607 1.000 rs2455331 chr5:643593 T/C cg24163568 chr5:669837 TPPP 0.39 8.26 0.41 3.2e-15 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs9583531 0.600 rs1441043 chr13:111367650 A/G cg15841412 chr13:111365552 ING1 0.51 6.46 0.33 3.53e-10 Coronary artery disease; LIHC cis rs9911578 1.000 rs9904879 chr17:56864422 G/A cg05425664 chr17:57184151 TRIM37 -0.58 -8.69 -0.43 1.55e-16 Intelligence (multi-trait analysis); LIHC cis rs2806561 0.704 rs667330 chr1:23515257 A/G cg12483005 chr1:23474871 LUZP1 0.45 7.08 0.36 8.24e-12 Height; LIHC cis rs7258465 1.000 rs10409505 chr19:18590251 C/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC cis rs11030122 0.632 rs11030599 chr11:4031677 A/G cg18678763 chr11:4115507 RRM1 -0.57 -8.46 -0.42 7.89e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs9309473 0.950 rs10189885 chr2:73877055 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.25 -0.32 1.23e-9 Metabolite levels; LIHC trans rs983392 0.679 rs72920867 chr11:60005424 T/C cg17275991 chr19:58003312 ZNF419 0.43 6.1 0.31 2.87e-9 Alzheimer's disease (late onset); LIHC cis rs8177179 0.565 rs4355280 chr3:133468425 A/G cg12373951 chr3:133503437 NA 0.45 7.25 0.36 2.84e-12 Iron status biomarkers (transferrin levels); LIHC cis rs6728642 0.803 rs11891457 chr2:97632449 G/T cg26665480 chr2:98280029 ACTR1B -0.58 -6.44 -0.33 3.96e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs8141529 0.748 rs132528 chr22:29295898 C/T cg15103426 chr22:29168792 CCDC117 -0.6 -9.63 -0.46 1.41e-19 Lymphocyte counts; LIHC cis rs7944584 0.611 rs10838696 chr11:47363285 A/G cg20307385 chr11:47447363 PSMC3 -0.59 -6.33 -0.32 7.77e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6840360 0.615 rs12647616 chr4:152607662 G/A cg22705602 chr4:152727874 NA -0.33 -6.81 -0.35 4.5e-11 Intelligence (multi-trait analysis); LIHC cis rs4595586 0.545 rs17546137 chr12:39401124 G/A cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs138880 0.505 rs56248708 chr22:50306969 G/A cg02269571 chr22:50332266 NA -1.03 -10.62 -0.5 5.67e-23 Schizophrenia; LIHC cis rs921968 0.541 rs17462853 chr2:219345637 T/G cg02985541 chr2:219472218 PLCD4 -0.42 -6.78 -0.34 5.31e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.51 0.62 1.6e-37 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg08219700 chr8:58056026 NA 0.52 7.12 0.36 6.34e-12 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.735 rs2790897 chr1:231491712 C/A cg06096015 chr1:231504339 EGLN1 0.5 9.2 0.45 3.59e-18 Hemoglobin concentration; LIHC cis rs10791323 0.660 rs10791330 chr11:133727535 C/T cg06766960 chr11:133703094 NA -0.61 -9.57 -0.46 2.2e-19 Childhood ear infection; LIHC cis rs7258465 0.965 rs7254249 chr19:18591745 G/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC cis rs9733 0.650 rs11204680 chr1:150587140 T/G cg13175981 chr1:150552382 MCL1 0.6 9.33 0.45 1.42e-18 Tonsillectomy; LIHC cis rs7223966 1.000 rs8081541 chr17:61812483 C/T cg05941027 chr17:61774174 LIMD2 0.36 7.54 0.38 4.22e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg10295955 chr4:187884368 NA 0.96 20.63 0.74 5.47e-62 Lobe attachment (rater-scored or self-reported); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg21551704 chr5:80550860 RNU5E;RNU5D;CKMT2 0.44 6.19 0.32 1.77e-9 Hepatitis; LIHC cis rs7927592 0.956 rs10896348 chr11:68357368 T/C cg20283391 chr11:68216788 NA -0.53 -8.12 -0.4 8.65e-15 Total body bone mineral density; LIHC cis rs758324 0.947 rs1948704 chr5:131171653 A/G cg06307176 chr5:131281290 NA 0.4 5.78 0.3 1.64e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg06873352 chr17:61820015 STRADA 0.76 13.44 0.59 2.3e-33 Prudent dietary pattern; LIHC cis rs10461617 0.541 rs832575 chr5:56161787 C/T cg12311346 chr5:56204834 C5orf35 -0.57 -6.2 -0.32 1.63e-9 Type 2 diabetes; LIHC cis rs7116495 1.000 rs12283462 chr11:71835406 T/G cg26138937 chr11:71823887 C11orf51 0.82 8.33 0.41 2.03e-15 Severe influenza A (H1N1) infection; LIHC cis rs68170813 0.605 rs74632724 chr7:107136759 A/G cg02696742 chr7:106810147 HBP1 -0.53 -6.08 -0.31 3.16e-9 Coronary artery disease; LIHC trans rs801193 1.000 rs4717319 chr7:66242593 A/G cg26939375 chr7:64535504 NA 0.43 6.82 0.35 4.11e-11 Aortic root size; LIHC cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg27297192 chr10:134578999 INPP5A 0.54 8.24 0.41 3.74e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1865760 0.566 rs7772312 chr6:26049616 G/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.74 0.3 2.07e-8 Height; LIHC cis rs1790761 0.692 rs1148883 chr11:67304686 A/G cg01069141 chr11:67398826 TBX10;NUDT8 0.36 6.34 0.32 7.21e-10 Mean corpuscular volume; LIHC cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.59 0.56 3.89e-30 Colorectal cancer; LIHC cis rs1538970 0.961 rs7543428 chr1:45839643 A/G cg05343316 chr1:45956843 TESK2 0.56 8.47 0.42 7.22e-16 Platelet count; LIHC cis rs9393692 0.902 rs6456711 chr6:26302572 A/C cg00631329 chr6:26305371 NA -0.51 -8.05 -0.4 1.38e-14 Educational attainment; LIHC cis rs965469 1.000 rs6037526 chr20:3251248 T/C cg25506879 chr20:3388711 C20orf194 -0.59 -6.84 -0.35 3.75e-11 IFN-related cytopenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09658576 chr7:139477957 TBXAS1;HIPK2 0.37 6.24 0.32 1.27e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.754 rs4896832 chr6:145964151 G/A cg23711669 chr6:146136114 FBXO30 0.72 13.18 0.58 2.28e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs9467711 0.559 rs2295593 chr6:26501768 C/T cg12826209 chr6:26865740 GUSBL1 0.57 5.84 0.3 1.2e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg11644478 chr21:40555479 PSMG1 0.74 8.98 0.44 1.92e-17 Cognitive function; LIHC cis rs875971 0.862 rs6958294 chr7:65794796 C/A cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs9682041 0.696 rs10936626 chr3:170095019 G/A cg11886554 chr3:170076028 SKIL 0.63 5.82 0.3 1.35e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs2070488 1.000 rs4147025 chr3:38456531 C/T cg24069376 chr3:38537580 EXOG 0.42 7.65 0.38 2.1e-13 Electrocardiographic conduction measures; LIHC trans rs1488564 1.000 rs1488564 chr3:173453868 A/G cg10986814 chr5:109025713 MAN2A1 -0.48 -6.51 -0.33 2.69e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg12310025 chr6:25882481 NA -0.67 -8.39 -0.41 1.28e-15 Intelligence (multi-trait analysis); LIHC cis rs6584283 0.716 rs10786558 chr10:101287610 G/A cg17888390 chr10:101282816 NA -0.31 -5.83 -0.3 1.31e-8 Ulcerative colitis; LIHC cis rs7106204 0.609 rs12791360 chr11:24286239 T/G ch.11.24196551F chr11:24239977 NA 0.66 6.44 0.33 4.03e-10 Response to Homoharringtonine (cytotoxicity); LIHC cis rs921968 0.643 rs3931102 chr2:219520405 C/T cg02985541 chr2:219472218 PLCD4 0.43 7.96 0.4 2.57e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs2257205 0.667 rs16943200 chr17:56829611 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.64 -0.34 1.21e-10 Pancreatic cancer; LIHC cis rs2067615 0.524 rs10778498 chr12:107063340 C/A cg15890332 chr12:107067104 RFX4 0.28 6.54 0.33 2.24e-10 Heart rate; LIHC cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg18252515 chr7:66147081 NA 1.27 16.79 0.67 1.38e-46 Diabetic kidney disease; LIHC cis rs4845459 0.967 rs4845453 chr1:152591953 C/G cg20634798 chr1:152595351 LCE3A -0.31 -6.13 -0.31 2.44e-9 Psoriasis; LIHC cis rs2839186 0.814 rs2839167 chr21:47661587 A/G cg09417038 chr21:47716443 C21orf57 -0.46 -6.76 -0.34 5.8200000000000003e-11 Testicular germ cell tumor; LIHC cis rs10193935 0.901 rs7570083 chr2:42517859 G/A cg27598129 chr2:42591480 NA -0.67 -10.45 -0.49 2.33e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs7095944 0.585 rs7080838 chr10:126419841 A/G cg20435097 chr10:126320824 FAM53B -0.35 -5.86 -0.3 1.09e-8 Asthma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03352657 chr17:26684557 POLDIP2;TMEM199 -0.45 -6.78 -0.34 5.41e-11 Pancreatic cancer; LIHC cis rs1707322 0.686 rs1250 chr1:46094027 A/G cg06784218 chr1:46089804 CCDC17 0.42 7.84 0.39 5.73e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs7512552 0.839 rs696616 chr1:150336173 G/A cg15654264 chr1:150340011 RPRD2 0.7 11.49 0.53 4.66e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs4638749 0.677 rs1522021 chr2:108833263 C/T cg25838818 chr2:108905173 SULT1C2 -0.4 -6.97 -0.35 1.69e-11 Blood pressure; LIHC cis rs6089584 0.888 rs2386555 chr20:60612373 C/T cg23262073 chr20:60523788 NA -0.29 -5.99 -0.31 5.42e-9 Body mass index; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.69 10.05 0.48 5.52e-21 Lymphocyte counts; LIHC cis rs4803468 1.000 rs2304242 chr19:41944616 G/T cg09537434 chr19:41945824 ATP5SL 1.02 21.29 0.75 1.19e-64 Height; LIHC cis rs782590 0.902 rs782595 chr2:55845596 C/G cg18811423 chr2:55921094 PNPT1 1.0 16.28 0.66 1.57e-44 Metabolic syndrome; LIHC trans rs8073060 0.504 rs225271 chr17:33969836 C/T cg19694781 chr19:47549865 TMEM160 -1.27 -14.1 -0.61 6.28e-36 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25916527 chr5:72292534 FCHO2 -0.41 -6.34 -0.32 7.31e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs428668 0.523 rs3926389 chr5:150677806 C/T cg14086364 chr5:150678334 SLC36A3 0.29 7.75 0.39 1.07e-13 Skin aging (microtopography measurement); LIHC cis rs1577917 0.958 rs12665542 chr6:86544443 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.55 -0.38 3.91e-13 Response to antipsychotic treatment; LIHC trans rs1814175 0.715 rs7479622 chr11:49673340 T/G cg15704280 chr7:45808275 SEPT13 -1.01 -21.86 -0.76 6.73e-67 Height; LIHC cis rs68170813 0.559 rs77605964 chr7:106962948 G/A cg02696742 chr7:106810147 HBP1 -0.5 -5.85 -0.3 1.17e-8 Coronary artery disease; LIHC cis rs7707921 0.752 rs2897554 chr5:81276241 C/T cg15871215 chr5:81402204 ATG10 0.6 6.93 0.35 2.17e-11 Breast cancer; LIHC cis rs10752881 1.000 rs10911190 chr1:182979080 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg25072359 chr17:41440525 NA 0.37 5.95 0.31 6.5e-9 Menopause (age at onset); LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.1e-13 Prudent dietary pattern; LIHC trans rs2727020 0.595 rs11040328 chr11:49339055 T/C cg15704280 chr7:45808275 SEPT13 -0.58 -9.0 -0.44 1.6e-17 Coronary artery disease; LIHC cis rs172166 0.694 rs188105 chr6:28071393 C/T cg16479474 chr6:28041457 NA 0.39 6.68 0.34 9.59e-11 Cardiac Troponin-T levels; LIHC cis rs6456156 0.565 rs6456153 chr6:167472167 T/C cg12798992 chr6:167411361 FGFR1OP 0.44 6.8 0.34 4.81e-11 Primary biliary cholangitis; LIHC cis rs12142240 0.659 rs111723629 chr1:46853361 G/T cg00530320 chr1:46809349 NSUN4 0.53 5.77 0.3 1.82e-8 Menopause (age at onset); LIHC cis rs11583043 1.000 rs17100939 chr1:101443701 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.12 0.31 2.57e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11110643 chr11:72929135 P2RY2 0.39 6.04 0.31 3.92e-9 Lung function (FEV1/FVC); LIHC cis rs2439831 0.850 rs28858500 chr15:44156942 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.59 0.42 3.02e-16 Lung cancer in ever smokers; LIHC cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg03060546 chr3:49711283 APEH 0.42 6.3 0.32 9.2e-10 Menarche (age at onset); LIHC cis rs6570726 0.791 rs10457788 chr6:145921136 T/A cg13319975 chr6:146136371 FBXO30 -0.43 -6.71 -0.34 8e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1023500 0.507 rs6002600 chr22:42488906 G/A cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Schizophrenia; LIHC trans rs1005277 0.579 rs2474594 chr10:38426661 G/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs9303280 0.901 rs7359623 chr17:38049589 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.72 0.3 2.32e-8 Self-reported allergy; LIHC cis rs1707322 0.964 rs10890358 chr1:46319025 T/A cg03146154 chr1:46216737 IPP 0.47 7.4 0.37 1.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1395 1.000 rs1275530 chr2:27432547 A/G cg23587288 chr2:27483067 SLC30A3 0.3 5.87 0.3 1.03e-8 Blood metabolite levels; LIHC cis rs1865760 0.927 rs6915834 chr6:25935427 A/C cg03517284 chr6:25882590 NA -0.44 -6.64 -0.34 1.21e-10 Height; LIHC cis rs2032447 0.575 rs198847 chr6:26106619 C/A cg18357526 chr6:26021779 HIST1H4A -0.81 -10.66 -0.5 4.21e-23 Intelligence (multi-trait analysis); LIHC cis rs1461503 0.932 rs56778812 chr11:122840491 C/T cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs72615157 0.634 rs2272343 chr7:99778285 A/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.55 5.79 0.3 1.57e-8 Lung function (FEV1/FVC); LIHC trans rs10411161 0.702 rs8110461 chr19:52383569 A/C cg22319618 chr22:45562946 NUP50 -0.6 -8.08 -0.4 1.13e-14 Breast cancer; LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg21448741 chr8:58168803 NA 0.37 6.87 0.35 3.11e-11 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.916 rs4142546 chr6:86505311 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.77 -0.39 9.02e-14 Response to antipsychotic treatment; LIHC cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg00684032 chr4:1343700 KIAA1530 0.5 7.63 0.38 2.36e-13 Obesity-related traits; LIHC cis rs16958440 0.867 rs74346439 chr18:44677467 G/C cg17192377 chr18:44677553 HDHD2 0.93 8.68 0.42 1.66e-16 Sitting height ratio; LIHC cis rs1144333 0.655 rs76532097 chr1:76320759 G/C cg03433033 chr1:76189801 ACADM 0.58 8.65 0.42 1.97e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs7412746 0.646 rs1972060 chr1:150937594 T/C cg15448220 chr1:150897856 SETDB1 0.39 6.14 0.32 2.24e-9 Melanoma; LIHC cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg20295408 chr7:1910781 MAD1L1 -0.46 -6.74 -0.34 6.65e-11 Bipolar disorder and schizophrenia; LIHC cis rs1878931 0.501 rs42329 chr16:3425524 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.69 -9.88 -0.47 2.07e-20 Body mass index (adult); LIHC cis rs7945718 0.591 rs7102432 chr11:12700132 T/C cg25843174 chr11:12811716 TEAD1 0.33 7.59 0.38 3.11e-13 Educational attainment (years of education); LIHC cis rs7187994 0.848 rs34923260 chr16:84773460 A/G cg07647771 chr16:84786436 USP10 -0.33 -5.73 -0.3 2.16e-8 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs1577917 0.917 rs35283633 chr6:86690787 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -9.97 -0.47 1.04e-20 Response to antipsychotic treatment; LIHC cis rs735396 1.000 rs2464195 chr12:121435475 G/A cg25281562 chr12:121454272 C12orf43 0.34 5.92 0.3 7.73e-9 N-glycan levels; LIHC cis rs10242455 0.702 rs3528 chr7:99055940 T/C cg18809830 chr7:99032528 PTCD1 -0.82 -6.37 -0.33 5.95e-10 Blood metabolite levels; LIHC cis rs6120849 0.754 rs6120813 chr20:33642112 T/C cg24642439 chr20:33292090 TP53INP2 0.66 7.21 0.36 3.58e-12 Protein C levels; LIHC cis rs4727027 0.870 rs1105261 chr7:148794442 T/G cg23583168 chr7:148888333 NA -0.69 -9.61 -0.46 1.67e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs10411161 1.000 rs8108583 chr19:52364977 C/A cg22319618 chr22:45562946 NUP50 -0.51 -6.91 -0.35 2.31e-11 Breast cancer; LIHC cis rs34330 0.562 rs17212236 chr12:12855483 G/C cg09462578 chr12:12878428 APOLD1 -0.8 -10.47 -0.49 1.9e-22 Systemic lupus erythematosus; LIHC trans rs11098499 0.739 rs10031033 chr4:120151452 C/T cg25214090 chr10:38739885 LOC399744 0.44 7.21 0.36 3.63e-12 Corneal astigmatism; LIHC cis rs1577917 0.958 rs884842 chr6:86680397 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.08 -0.48 4.45e-21 Response to antipsychotic treatment; LIHC cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg05590025 chr7:65112418 INTS4L2 0.66 7.29 0.37 2.21e-12 Diabetic kidney disease; LIHC cis rs919433 1.000 rs919433 chr2:198166565 G/A cg03934865 chr2:198174659 NA -0.59 -9.6 -0.46 1.74e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9348739 1 rs9348739 chr6:26923099 G/C cg12826209 chr6:26865740 GUSBL1 0.76 7.5 0.38 5.53e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs933688 1.000 rs11959525 chr5:90703840 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.65 0.73 4.7e-58 Smoking behavior; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24174984 chr2:29117731 WDR43 -0.46 -6.44 -0.33 4.09e-10 Pancreatic cancer; LIHC cis rs9733 0.650 rs11204684 chr1:150608894 A/G cg18016565 chr1:150552671 MCL1 -0.56 -11.21 -0.52 4.68e-25 Tonsillectomy; LIHC cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg16405210 chr4:1374714 KIAA1530 0.42 6.3 0.32 9.07e-10 Obesity-related traits; LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg13395646 chr4:1353034 KIAA1530 -0.44 -6.16 -0.32 2.03e-9 Longevity; LIHC cis rs9443189 1.000 rs1280047 chr6:76527791 A/G cg01950844 chr6:76311363 SENP6 0.52 6.45 0.33 3.76e-10 Prostate cancer; LIHC cis rs10751667 0.666 rs7396059 chr11:970490 C/A ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs709400 0.567 rs1961600 chr14:103862144 G/A cg26031613 chr14:104095156 KLC1 0.79 9.94 0.47 1.29e-20 Body mass index; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.97 -0.31 5.99e-9 Total body bone mineral density; LIHC cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg13409248 chr3:40428643 ENTPD3 -0.42 -6.95 -0.35 1.81e-11 Renal cell carcinoma; LIHC cis rs11588062 0.601 rs11579255 chr1:46806959 C/T cg23431851 chr1:46668822 C1orf190;POMGNT1 0.45 7.21 0.36 3.57e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg08219700 chr8:58056026 NA 0.5 6.13 0.31 2.49e-9 Developmental language disorder (linguistic errors); LIHC cis rs1059312 0.808 rs2170989 chr12:129291317 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.76 16.6 0.67 8e-46 Systemic lupus erythematosus; LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg22907277 chr7:1156413 C7orf50 0.51 7.87 0.39 4.79e-14 Longevity;Endometriosis; LIHC cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg02951883 chr7:2050386 MAD1L1 -0.68 -11.32 -0.52 1.9e-25 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs1577917 1.000 rs6940458 chr6:86644992 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -7.03 -0.36 1.15e-11 Response to antipsychotic treatment; LIHC cis rs2439831 0.681 rs498837 chr15:43608024 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.78 11.85 0.54 2.19e-27 Lung cancer in ever smokers; LIHC cis rs12477438 0.765 rs7605734 chr2:99644068 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.2 -0.41 4.92e-15 Chronic sinus infection; LIHC cis rs8072100 0.539 rs36043200 chr17:45629406 G/A cg08085267 chr17:45401833 C17orf57 0.57 8.58 0.42 3.35e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs8177179 0.967 rs4287912 chr3:133437778 A/G cg18769074 chr3:133464867 TF 0.26 5.82 0.3 1.32e-8 Iron status biomarkers (transferrin levels); LIHC cis rs74417235 0.528 rs9324789 chr5:154074362 C/T cg08754654 chr5:154026448 NA -0.28 -5.87 -0.3 1.05e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs1707322 0.896 rs785518 chr1:46568422 A/T cg03146154 chr1:46216737 IPP -0.45 -7.26 -0.37 2.61e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6442522 0.809 rs17041143 chr3:15485845 C/G cg16303742 chr3:15540471 COLQ 0.39 6.15 0.32 2.11e-9 Uric acid levels; LIHC cis rs3806843 1.000 rs11167609 chr5:140200426 T/G cg19875535 chr5:140030758 IK 0.35 5.75 0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs6912958 0.525 rs59322 chr6:88020521 C/A cg12350822 chr6:88032061 C6orf162;GJB7 0.34 6.58 0.33 1.82e-10 Monocyte percentage of white cells; LIHC cis rs1113500 0.897 rs2336127 chr1:108640870 G/A cg06207961 chr1:108661230 NA 0.37 7.29 0.37 2.18e-12 Growth-regulated protein alpha levels; LIHC cis rs77633900 0.772 rs166933 chr15:76736265 G/A cg21673338 chr15:77095150 SCAPER -0.53 -5.92 -0.3 7.98e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs1801251 0.778 rs2675967 chr2:233736133 C/G cg25237894 chr2:233734115 C2orf82 -0.59 -11.37 -0.52 1.22e-25 Coronary artery disease; LIHC cis rs2274273 0.682 rs1201378 chr14:55493408 A/G cg01864836 chr14:55583639 NA 0.34 5.88 0.3 9.74e-9 Protein biomarker; LIHC cis rs1816752 0.905 rs9511264 chr13:25012217 C/T cg22771759 chr13:24902376 NA -0.32 -6.81 -0.35 4.43e-11 Obesity-related traits; LIHC cis rs876084 0.505 rs9969405 chr8:121107146 A/G cg06265175 chr8:121136014 COL14A1 0.48 7.72 0.39 1.34e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs35883536 1.000 rs2297715 chr1:101092594 A/G cg14515779 chr1:101123966 NA -0.67 -13.11 -0.58 4.4e-32 Monocyte count; LIHC cis rs11677370 0.561 rs13015012 chr2:3821252 C/G cg17052675 chr2:3827356 NA 0.57 7.67 0.38 1.79e-13 Type 2 diabetes; LIHC cis rs4450131 0.522 rs3781455 chr10:126347688 T/C cg20435097 chr10:126320824 FAM53B 0.68 12.41 0.56 1.85e-29 White blood cell count (basophil); LIHC cis rs7762018 0.607 rs80267898 chr6:170040306 G/A cg19338460 chr6:170058176 WDR27 -0.88 -8.92 -0.43 2.97e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11711311 1.000 rs9854504 chr3:113532381 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.4 7.26 0.37 2.61e-12 IgG glycosylation; LIHC cis rs875971 0.964 rs11765965 chr7:65842221 A/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs8067354 0.645 rs72838857 chr17:57836767 A/G cg13753209 chr17:57696993 CLTC 0.76 12.15 0.55 1.75e-28 Hemoglobin concentration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08031094 chr2:54013912 LOC100302652;ASB3;ERLEC1 0.46 6.25 0.32 1.22e-9 Lung function (FEV1/FVC); LIHC cis rs7607369 0.596 rs56304256 chr2:219276138 T/C cg02176678 chr2:219576539 TTLL4 -0.52 -7.16 -0.36 4.89e-12 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs3008870 1.000 rs2985811 chr1:67377722 G/T cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.29e-8 Lymphocyte percentage of white cells; LIHC cis rs6714710 0.535 rs13033383 chr2:98339513 C/T cg26665480 chr2:98280029 ACTR1B 0.53 6.08 0.31 3.17e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs2066819 1.000 rs2066818 chr12:56753822 C/A cg26734620 chr12:56694298 CS 1.21 10.14 0.48 2.67e-21 Psoriasis vulgaris; LIHC cis rs7772486 0.875 rs2777479 chr6:146309178 C/A cg23711669 chr6:146136114 FBXO30 0.59 10.21 0.48 1.6e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs35306767 0.903 rs11813210 chr10:919796 G/A cg20503657 chr10:835505 NA 1.07 12.48 0.56 9.98e-30 Eosinophil percentage of granulocytes; LIHC cis rs3749237 0.615 rs11130202 chr3:49566715 C/T cg03060546 chr3:49711283 APEH 0.63 10.2 0.48 1.63e-21 Resting heart rate; LIHC cis rs17376456 0.825 rs13357713 chr5:93145423 T/C cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg05552183 chr6:42928497 GNMT 0.68 10.31 0.49 7.18e-22 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs921968 0.643 rs711191 chr2:219386084 T/A cg18887096 chr2:219472410 PLCD4 0.36 6.46 0.33 3.52e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2370759 0.898 rs113412621 chr10:32579306 C/T cg01819863 chr10:32635814 EPC1 1.11 16.43 0.66 3.99e-45 Sexual dysfunction (female); LIHC cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg25072359 chr17:41440525 NA 0.36 5.76 0.3 1.89e-8 Menopause (age at onset); LIHC cis rs4474465 1.000 rs7935180 chr11:78169785 C/T cg02023728 chr11:77925099 USP35 0.35 6.29 0.32 9.61e-10 Alzheimer's disease (survival time); LIHC cis rs7312933 0.558 rs11181467 chr12:42765250 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.93 0.39 3.1e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4631830 0.863 rs10826127 chr10:51530757 G/A cg20129853 chr10:51489980 NA -0.41 -9.04 -0.44 1.2e-17 Prostate-specific antigen levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06116495 chr3:112280886 ATG3;SLC35A5 -0.5 -6.3 -0.32 9.09e-10 Systolic blood pressure; LIHC cis rs5769765 0.773 rs7410291 chr22:50300078 A/G cg02269571 chr22:50332266 NA -0.61 -8.73 -0.43 1.13e-16 Schizophrenia; LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg06873352 chr17:61820015 STRADA 0.73 13.06 0.58 6.74e-32 Prudent dietary pattern; LIHC cis rs7903847 0.642 rs10882923 chr10:99159018 G/A cg06359132 chr10:99160096 RRP12 -0.41 -6.41 -0.33 4.83e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7072216 0.763 rs9787550 chr10:100169051 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.34 -0.32 7.28e-10 Metabolite levels; LIHC cis rs12464559 0.649 rs9287998 chr2:152621356 C/T cg01189475 chr2:152685088 ARL5A 0.63 7.46 0.37 7.1e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10625758 chr17:73851514 WBP2 0.45 6.14 0.32 2.31e-9 Lung function (FEV1/FVC); LIHC cis rs2749592 0.531 rs994804 chr10:37900140 A/C cg25427524 chr10:38739819 LOC399744 0.57 10.29 0.49 7.98e-22 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs67460515 0.529 rs6441364 chr3:160897915 A/C cg22828804 chr20:3140466 UBOX5;FASTKD5 0.39 6.06 0.31 3.57e-9 Parkinson's disease; LIHC trans rs1814175 0.676 rs1721999 chr11:49917372 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs600626 0.636 rs10899110 chr11:75452342 C/G cg24262691 chr11:75473276 NA 0.39 5.91 0.3 8.34e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs4268898 0.931 rs7603997 chr2:24524958 C/T cg06627628 chr2:24431161 ITSN2 -0.55 -7.95 -0.4 2.69e-14 Asthma; LIHC cis rs12079745 0.793 rs12092506 chr1:169405517 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.71 -6.87 -0.35 2.99e-11 QT interval; LIHC cis rs72627509 0.951 rs72627508 chr4:57831564 C/G cg26694713 chr4:57773883 REST 0.65 8.98 0.44 1.83e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1475718 0.563 rs1041608 chr9:137116205 C/T cg21243944 chr9:137118148 NA -0.57 -8.14 -0.4 7.24e-15 Immature fraction of reticulocytes;Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs644799 0.932 rs523934 chr11:95641775 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.47 6.4 0.33 5.13e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg04267008 chr7:1944627 MAD1L1 -0.7 -11.24 -0.52 3.81e-25 Bipolar disorder and schizophrenia; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg21784052 chr20:47835958 DDX27 0.52 6.23 0.32 1.34e-9 Glycated hemoglobin levels; LIHC cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.72 12.48 0.56 1.05e-29 Colorectal cancer; LIHC cis rs992157 0.835 rs4674282 chr2:219144230 A/T cg00012203 chr2:219082015 ARPC2 -0.81 -12.98 -0.57 1.34e-31 Colorectal cancer; LIHC cis rs561341 1.000 rs4795669 chr17:30244701 C/T cg13647721 chr17:30228624 UTP6 0.79 7.44 0.37 8.4e-13 Hip circumference adjusted for BMI; LIHC cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg05368731 chr17:41323189 NBR1 0.73 12.11 0.55 2.4e-28 Menopause (age at onset); LIHC cis rs4919694 0.572 rs4917995 chr10:104845443 A/T cg04362960 chr10:104952993 NT5C2 -0.79 -7.14 -0.36 5.57e-12 Arsenic metabolism; LIHC cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg13770153 chr20:60521292 NA -0.35 -7.06 -0.36 9.2e-12 Body mass index; LIHC cis rs2073300 1.000 rs6132623 chr20:23442324 T/A cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs17685 0.523 rs10246583 chr7:75746667 C/A cg19862616 chr7:65841803 NCRNA00174 0.91 18.79 0.71 1.31e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs244293 0.730 rs2332314 chr17:53033007 T/G cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.07 -0.31 3.48e-9 Menarche (age at onset); LIHC cis rs250677 0.687 rs384979 chr5:148459267 C/T cg12140854 chr5:148520817 ABLIM3 0.45 6.11 0.31 2.64e-9 Breast cancer; LIHC cis rs2425143 0.598 rs2425118 chr20:34324098 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.47e-16 Blood protein levels; LIHC cis rs8058578 1.000 rs7204278 chr16:30730274 A/G cg02466173 chr16:30829666 NA -0.44 -7.1 -0.36 7.13e-12 Multiple myeloma; LIHC cis rs17685 0.587 rs1623759 chr7:75724679 A/T cg01364799 chr7:75623366 TMEM120A -0.5 -7.41 -0.37 9.97e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs875971 0.964 rs60193905 chr7:65971260 A/G cg11764359 chr7:65958608 NA 0.91 16.81 0.67 1.25e-46 Aortic root size; LIHC cis rs35306767 0.807 rs11253513 chr10:968450 C/T cg26597838 chr10:835615 NA 0.96 11.79 0.54 3.72e-27 Eosinophil percentage of granulocytes; LIHC cis rs10492096 0.783 rs11064220 chr12:6592574 C/T cg13857086 chr12:6580257 VAMP1 0.56 5.94 0.31 7.12e-9 Hip geometry; LIHC cis rs7662987 0.540 rs2851257 chr4:100039499 G/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs8017423 0.900 rs7141887 chr14:90705364 G/T cg04374321 chr14:90722782 PSMC1 0.75 14.41 0.61 4.2e-37 Mortality in heart failure; LIHC cis rs208520 1.000 rs72882086 chr6:66976671 G/A cg07460842 chr6:66804631 NA 0.69 7.27 0.37 2.52e-12 Exhaled nitric oxide output; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg20957396 chr2:135062876 MGAT5 0.35 6.35 0.32 6.78e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6570726 0.935 rs421690 chr6:145834594 A/C cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC trans rs3749237 0.964 rs1799843 chr3:49849723 G/A cg21659725 chr3:3221576 CRBN 0.78 12.12 0.55 2.34e-28 Resting heart rate; LIHC cis rs3845702 0.736 rs2678936 chr2:180872179 G/C cg01881094 chr2:180872142 CWC22 1.15 10.34 0.49 5.55e-22 Schizophrenia; LIHC cis rs17102423 0.755 rs7154852 chr14:65553822 C/A cg11161011 chr14:65562177 MAX -0.52 -7.49 -0.38 6.09e-13 Obesity-related traits; LIHC trans rs10242455 0.571 rs55830753 chr7:99292222 A/G cg09045935 chr12:6379348 NA 0.74 6.16 0.32 2.03e-9 Blood metabolite levels; LIHC cis rs7534824 0.582 rs17448827 chr1:101421407 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 7.48 0.38 6.25e-13 Refractive astigmatism; LIHC cis rs709400 0.628 rs6575983 chr14:103869849 C/G cg26031613 chr14:104095156 KLC1 0.71 9.32 0.45 1.5e-18 Body mass index; LIHC cis rs1348850 0.914 rs7573763 chr2:178249808 C/T cg27490568 chr2:178487706 NA 0.38 6.03 0.31 4.34e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs1005277 0.579 rs2505198 chr10:38393183 A/C cg17830980 chr10:43048298 ZNF37B -0.53 -10.74 -0.5 2.25e-23 Extrinsic epigenetic age acceleration; LIHC cis rs910316 0.503 rs4903273 chr14:75441795 G/A cg11812906 chr14:75593930 NEK9 -0.68 -12.07 -0.55 3.38e-28 Height; LIHC cis rs7086627 0.515 rs11202963 chr10:82210392 A/G cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06897120 chr16:4613204 LOC342346 0.37 6.39 0.33 5.33e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7903847 0.642 rs10882926 chr10:99160690 C/T cg20016023 chr10:99160130 RRP12 0.38 5.96 0.31 6.31e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6504950 0.800 rs9891704 chr17:53010755 A/G cg10237252 chr17:52977213 TOM1L1 -0.34 -5.99 -0.31 5.22e-9 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13095604 chr12:12966124 DDX47 0.43 6.46 0.33 3.7e-10 Cognitive function; LIHC cis rs7607369 0.609 rs13391398 chr2:219282429 A/G cg02176678 chr2:219576539 TTLL4 0.5 7.17 0.36 4.71e-12 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs3008870 1.000 rs12137403 chr1:67437043 C/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.9 -0.3 8.84e-9 Lymphocyte percentage of white cells; LIHC cis rs3741404 0.825 rs11603384 chr11:63949095 G/A cg04317338 chr11:64019027 PLCB3 0.5 6.84 0.35 3.68e-11 Platelet count; LIHC cis rs7250872 0.647 rs2304613 chr19:1817943 G/C cg18850929 chr19:1828978 REXO1 0.39 6.45 0.33 3.92e-10 Bipolar disorder; LIHC cis rs7959452 0.570 rs10878964 chr12:69720691 T/G cg22834771 chr12:69754056 YEATS4 -0.49 -8.47 -0.42 7.15e-16 Blood protein levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18088712 chr1:16810147 CROCCL2 -0.43 -6.6 -0.34 1.53e-10 Calcium levels; LIHC cis rs1005277 0.579 rs2749616 chr10:38510993 A/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.49e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.6 8.72 0.43 1.24e-16 Lymphocyte counts; LIHC cis rs6598955 0.724 rs12732295 chr1:26602251 C/T cg00852783 chr1:26633632 UBXN11 0.51 8.61 0.42 2.62e-16 Obesity-related traits; LIHC cis rs965469 0.779 rs6051746 chr20:3307290 C/G cg25506879 chr20:3388711 C20orf194 -0.51 -6.33 -0.32 7.55e-10 IFN-related cytopenia; LIHC cis rs9916302 0.784 rs34473775 chr17:37396201 G/T cg00129232 chr17:37814104 STARD3 -0.4 -6.38 -0.33 5.87e-10 Glomerular filtration rate (creatinine); LIHC cis rs2239547 0.562 rs2581810 chr3:52960859 C/T cg11645453 chr3:52864694 ITIH4 -0.24 -6.1 -0.31 2.86e-9 Schizophrenia; LIHC cis rs929354 0.772 rs3802120 chr7:156977794 C/T cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs903552 0.935 rs4965871 chr15:102003810 A/T cg00659931 chr15:102010125 PCSK6 -0.45 -6.31 -0.32 8.74e-10 Diabetic kidney disease; LIHC cis rs11190604 0.767 rs7392696 chr10:102182141 G/A cg07080220 chr10:102295463 HIF1AN 0.47 6.87 0.35 3.04e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg06873352 chr17:61820015 STRADA 0.7 11.94 0.54 1.07e-27 Prudent dietary pattern; LIHC trans rs11148252 1.000 rs4886018 chr13:52990717 C/T cg18335740 chr13:41363409 SLC25A15 0.36 6.37 0.33 6.11e-10 Lewy body disease; LIHC cis rs1023500 0.596 rs133352 chr22:42434022 C/A cg04733989 chr22:42467013 NAGA 0.67 9.58 0.46 2.05e-19 Schizophrenia; LIHC cis rs12824058 0.798 rs7968728 chr12:130804696 T/A cg24838063 chr12:130822603 PIWIL1 0.66 9.12 0.44 6.48e-18 Menopause (age at onset); LIHC cis rs13161895 1.000 rs394616 chr5:179418134 T/G cg02702477 chr5:179499311 RNF130 0.75 10.3 0.49 7.38e-22 LDL cholesterol; LIHC cis rs1775715 0.835 rs11008701 chr10:32241096 A/G cg14930904 chr10:32216787 ARHGAP12 0.39 7.05 0.36 1.02e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs1801251 1.000 rs1947105 chr2:233721455 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.35 0.52 1.46e-25 Coronary artery disease; LIHC cis rs13161895 1.000 rs4129403 chr5:179476610 A/G cg02702477 chr5:179499311 RNF130 0.83 11.48 0.53 4.88e-26 LDL cholesterol; LIHC cis rs8062405 0.824 rs4788083 chr16:28545449 A/G cg07451762 chr16:28383216 NA 0.32 6.59 0.34 1.62e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg06420487 chr17:61919686 SMARCD2 0.42 5.78 0.3 1.69e-8 Height; LIHC cis rs8077889 1.000 rs8077889 chr17:41878166 G/T cg26893861 chr17:41843967 DUSP3 -0.85 -9.53 -0.46 3.03e-19 Triglycerides; LIHC cis rs17685 0.784 rs1637043 chr7:75699099 G/A cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8017423 0.935 rs11159959 chr14:90733656 C/T cg14092571 chr14:90743983 NA 0.47 7.24 0.36 2.98e-12 Mortality in heart failure; LIHC cis rs1475911 0.671 rs12483409 chr21:43521902 G/A cg19766460 chr21:43528205 UMODL1;C21orf128 1.11 18.51 0.71 1.7e-53 IgG glycosylation; LIHC cis rs6598955 0.614 rs1134584 chr1:26608828 G/A cg04990556 chr1:26633338 UBXN11 -0.62 -10.04 -0.48 5.96e-21 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09477292 chr4:6577027 MAN2B2 0.52 7.27 0.37 2.47e-12 Lung function (FEV1/FVC); LIHC trans rs1814175 0.645 rs28436748 chr11:50046422 G/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg06481639 chr22:41940642 POLR3H 0.71 7.17 0.36 4.8e-12 Vitiligo; LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.62 10.36 0.49 4.65e-22 Glycated hemoglobin levels; LIHC cis rs798554 1.000 rs798544 chr7:2763102 A/G cg19346786 chr7:2764209 NA 0.45 6.8 0.34 4.82e-11 Height; LIHC cis rs2197308 0.549 rs10785517 chr12:38577992 G/T cg26384229 chr12:38710491 ALG10B 0.4 6.08 0.31 3.29e-9 Morning vs. evening chronotype; LIHC trans rs875971 0.545 rs6460298 chr7:65907770 T/C cg26939375 chr7:64535504 NA 0.42 6.63 0.34 1.32e-10 Aortic root size; LIHC cis rs644799 1.000 rs474252 chr11:95619292 G/C cg25478527 chr11:95522999 CEP57;FAM76B 0.43 5.85 0.3 1.14e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg23262073 chr20:60523788 NA -0.38 -7.69 -0.38 1.59e-13 Obesity-related traits; LIHC cis rs9948 0.786 rs62156225 chr2:97414118 T/C cg01990225 chr2:97406019 LMAN2L -0.72 -6.23 -0.32 1.37e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.78 0.69 1.5e-50 Gut microbiome composition (summer); LIHC cis rs763121 0.853 rs5757253 chr22:39104320 C/T cg14440974 chr22:39074834 NA -0.37 -6.17 -0.32 1.98e-9 Menopause (age at onset); LIHC cis rs7959452 0.640 rs1598543 chr12:69688757 G/T cg14784868 chr12:69753453 YEATS4 0.88 16.91 0.67 4.65e-47 Blood protein levels; LIHC cis rs7520050 0.933 rs4504835 chr1:46455571 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.44 6.46 0.33 3.66e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2991971 0.716 rs7532573 chr1:45915892 A/T cg15605315 chr1:45957053 TESK2 -0.51 -7.15 -0.36 5.41e-12 High light scatter reticulocyte count; LIHC cis rs4700695 0.614 rs153387 chr5:65422236 G/A cg21114390 chr5:65439923 SFRS12 -0.54 -6.04 -0.31 4.07e-9 Facial morphology (factor 19); LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg14709524 chr16:89940631 TCF25 0.57 7.28 0.37 2.27e-12 Skin colour saturation; LIHC cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.15e-9 Menopause (age at onset); LIHC cis rs2708977 0.966 rs2708978 chr2:97202243 A/C cg01950434 chr2:97203154 ARID5A -0.54 -8.16 -0.4 6.28e-15 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs7572733 0.534 rs1401091 chr2:198790423 T/G cg00792783 chr2:198669748 PLCL1 -0.45 -6.66 -0.34 1.09e-10 Dermatomyositis; LIHC cis rs11640734 0.609 rs11647746 chr16:89806343 C/A cg04013166 chr16:89971882 TCF25 0.48 6.02 0.31 4.62e-9 Interleukin-17 levels; LIHC cis rs2072499 0.750 rs55910626 chr1:156159909 C/G cg25208724 chr1:156163844 SLC25A44 0.72 8.0 0.4 2e-14 Testicular germ cell tumor; LIHC cis rs992157 0.710 rs10167446 chr2:219056866 A/G cg00012203 chr2:219082015 ARPC2 0.84 14.44 0.62 3.23e-37 Colorectal cancer; LIHC cis rs9467773 1.000 rs1321480 chr6:26532742 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.76 0.6 1.32e-34 Intelligence (multi-trait analysis); LIHC cis rs8060686 0.545 rs3826164 chr16:68280317 A/G cg05110241 chr16:68378359 PRMT7 0.61 6.89 0.35 2.74e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs2302190 1.000 rs2302190 chr17:56584508 A/G cg05425664 chr17:57184151 TRIM37 -0.46 -5.88 -0.3 9.65e-9 Vitamin D levels; LIHC cis rs12824058 1.000 rs12824058 chr12:130804334 A/G cg24229701 chr12:130821962 PIWIL1 0.4 5.82 0.3 1.37e-8 Menopause (age at onset); LIHC cis rs4665809 0.878 rs4665826 chr2:26367503 A/T cg25036284 chr2:26402008 FAM59B 0.51 5.87 0.3 1.03e-8 Gut microbiome composition (summer); LIHC trans rs7674212 0.537 rs2623060 chr4:104047504 G/A cg16471864 chr4:38666270 KLF3;FLJ13197 -0.43 -6.11 -0.31 2.76e-9 Type 2 diabetes; LIHC cis rs655641 0.823 rs2458493 chr11:85783875 A/G cg09030501 chr11:85779252 PICALM -0.5 -5.89 -0.3 9.43e-9 Platelet count; LIHC trans rs875971 0.660 rs7807944 chr7:66087195 C/G cg26939375 chr7:64535504 NA -0.43 -6.98 -0.35 1.57e-11 Aortic root size; LIHC cis rs6430585 0.646 rs12468768 chr2:136494985 C/T cg07169764 chr2:136633963 MCM6 1.16 16.23 0.66 2.6e-44 Corneal structure; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg09774412 chr22:50902130 SBF1 0.39 6.5 0.33 2.81e-10 Eotaxin levels; LIHC trans rs2243480 1.000 rs2420170 chr7:65656053 T/C cg10756647 chr7:56101905 PSPH -1.08 -13.18 -0.58 2.26e-32 Diabetic kidney disease; LIHC cis rs950169 1.000 rs62026530 chr15:84775840 G/T cg17507749 chr15:85114479 UBE2QP1 0.76 7.75 0.39 1.03e-13 Schizophrenia; LIHC cis rs6714710 0.603 rs2044458 chr2:98377512 A/T cg26665480 chr2:98280029 ACTR1B 0.45 6.41 0.33 4.73e-10 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs4243830 0.850 rs1064835 chr1:6585539 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.73 8.86 0.43 4.42e-17 Body mass index; LIHC cis rs7615952 0.599 rs2270986 chr3:125701099 T/C cg05084668 chr3:125655381 ALG1L -0.43 -6.85 -0.35 3.45e-11 Blood pressure (smoking interaction); LIHC cis rs3812111 0.899 rs9488836 chr6:116435795 C/T cg08036074 chr6:116424633 NT5DC1 -0.66 -11.48 -0.53 5.16e-26 Age-related macular degeneration; LIHC cis rs35883536 0.647 rs17402630 chr1:101046587 C/T cg14515779 chr1:101123966 NA 0.5 6.9 0.35 2.49e-11 Monocyte count; LIHC cis rs918629 0.679 rs72656689 chr5:95270872 A/G cg10483112 chr5:95245456 ELL2 -0.37 -6.32 -0.32 8.28e-10 IgG glycosylation; LIHC cis rs933688 1.000 rs10073935 chr5:90742188 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.82 0.69 1.01e-50 Smoking behavior; LIHC trans rs214034 0.825 rs2710675 chr2:17848189 T/C cg09061216 chr1:1558936 MIB2 0.51 6.04 0.31 4.01e-9 Response to amphetamines; LIHC cis rs35306767 0.855 rs55697724 chr10:885622 T/C cg26597838 chr10:835615 NA 1.49 17.34 0.68 8.86e-49 Eosinophil percentage of granulocytes; LIHC cis rs921968 0.541 rs581013 chr2:219432040 G/T cg02176678 chr2:219576539 TTLL4 0.53 7.43 0.37 8.67e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs597539 0.652 rs496616 chr11:68672800 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.04 0.51 1.93e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg16262614 chr3:133464971 TF 0.28 6.48 0.33 3.29e-10 Iron status biomarkers; LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg10150615 chr22:24372951 LOC391322 -0.55 -7.92 -0.39 3.25e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1568889 1.000 rs12803716 chr11:28055111 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.81 0.35 4.36e-11 Bipolar disorder; LIHC cis rs929354 0.772 rs3802117 chr7:156987000 C/T cg05182265 chr7:156933206 UBE3C -0.32 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs6466055 0.720 rs62484712 chr7:105005741 G/A cg04380332 chr7:105027541 SRPK2 -0.37 -6.9 -0.35 2.52e-11 Schizophrenia; LIHC cis rs1419980 0.630 rs2080126 chr12:7774524 A/C cg10578777 chr12:7781093 NA 0.5 8.9 0.43 3.35e-17 HDL cholesterol levels; LIHC cis rs916888 0.821 rs199507 chr17:44858855 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7592578 1.000 rs7592578 chr2:191439591 T/G cg10560079 chr2:191398806 TMEM194B 0.88 12.12 0.55 2.3e-28 Diastolic blood pressure; LIHC cis rs4975616 0.839 rs2447853 chr5:1333077 A/G cg07493874 chr5:1342172 CLPTM1L -0.67 -10.82 -0.51 1.12e-23 Lung cancer; LIHC cis rs11583043 0.918 rs17525451 chr1:101422409 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.18 0.44 4.07e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs614226 0.935 rs588132 chr12:121024066 A/G cg27489772 chr12:121021490 NA 0.53 5.84 0.3 1.23e-8 Type 1 diabetes nephropathy; LIHC cis rs10791323 0.569 rs2257004 chr11:133712473 C/T cg06766960 chr11:133703094 NA -0.65 -10.93 -0.51 4.88e-24 Childhood ear infection; LIHC trans rs61931739 0.534 rs2389276 chr12:34097891 T/C cg26384229 chr12:38710491 ALG10B 0.46 6.47 0.33 3.3e-10 Morning vs. evening chronotype; LIHC cis rs8114671 0.562 rs6120757 chr20:33488771 C/T cg07148914 chr20:33460835 GGT7 0.65 9.85 0.47 2.6e-20 Height; LIHC cis rs1198430 0.599 rs946269 chr1:23769359 T/C cg19827787 chr1:23763612 ASAP3 0.28 6.15 0.32 2.22e-9 Total cholesterol levels; LIHC cis rs250677 0.687 rs250666 chr5:148454622 A/G cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC cis rs6762 0.550 rs8672 chr11:838634 C/G cg16425592 chr11:842748 TSPAN4;POLR2L -0.78 -9.44 -0.45 6.04e-19 Mean platelet volume; LIHC trans rs7615952 0.932 rs13086087 chr3:125646281 A/C cg07211511 chr3:129823064 LOC729375 -0.84 -10.37 -0.49 4.23e-22 Blood pressure (smoking interaction); LIHC cis rs4975616 0.804 rs31489 chr5:1342714 C/A cg07493874 chr5:1342172 CLPTM1L -0.65 -10.44 -0.49 2.5e-22 Lung cancer; LIHC cis rs11792861 0.888 rs57314245 chr9:111813832 G/A cg05043794 chr9:111880884 C9orf5 -0.26 -5.86 -0.3 1.08e-8 Menarche (age at onset); LIHC cis rs7618501 0.573 rs2624824 chr3:50088266 T/C cg24110177 chr3:50126178 RBM5 0.5 8.16 0.4 6.38e-15 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC trans rs60843830 1.000 rs62114505 chr2:242426 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.67 9.6 0.46 1.74e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC trans rs12478296 0.901 rs59477854 chr2:243015490 T/C cg01596870 chr19:55963115 NA -0.67 -9.5 -0.46 3.67e-19 Obesity-related traits; LIHC cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg12310025 chr6:25882481 NA 0.59 8.37 0.41 1.49e-15 Blood metabolite levels; LIHC cis rs9399135 0.904 rs4895438 chr6:135317665 G/T cg24558204 chr6:135376177 HBS1L 0.39 6.37 0.33 6.02e-10 Red blood cell count; LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg06873352 chr17:61820015 STRADA 0.74 13.05 0.58 7.39e-32 Prudent dietary pattern; LIHC cis rs870825 0.616 rs35533356 chr4:185639134 A/G cg04058563 chr4:185651563 MLF1IP 0.77 7.79 0.39 8.15e-14 Blood protein levels; LIHC cis rs9399135 0.967 rs6909975 chr6:135315570 C/T cg24558204 chr6:135376177 HBS1L 0.38 6.33 0.32 7.67e-10 Red blood cell count; LIHC cis rs858239 0.665 rs858305 chr7:23242830 C/G cg18081818 chr7:23246105 NA 0.41 6.34 0.32 7.16e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2832191 0.692 rs2254872 chr21:30414724 C/T cg24692254 chr21:30365293 RNF160 0.87 15.78 0.65 1.55e-42 Dental caries; LIHC cis rs765787 0.530 rs4444275 chr15:45535347 T/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16466278 chr15:43429893 TMEM62 0.41 6.73 0.34 7.12e-11 Longevity; LIHC cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg07424592 chr7:64974309 NA 0.76 8.84 0.43 5.28e-17 Diabetic kidney disease; LIHC cis rs12286929 0.736 rs11215397 chr11:115044076 G/A cg04055981 chr11:115044050 NA 0.53 8.55 0.42 4.25e-16 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2836950 0.501 rs35994303 chr21:40686020 C/T cg11890956 chr21:40555474 PSMG1 -0.44 -7.05 -0.36 9.71e-12 Menarche (age at onset); LIHC cis rs8067354 0.645 rs2665403 chr17:57889985 G/A cg13753209 chr17:57696993 CLTC 0.77 12.28 0.55 6.02e-29 Hemoglobin concentration; LIHC cis rs9814567 1.000 rs13322305 chr3:134310791 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs79149102 0.579 rs74023935 chr15:75359184 T/C cg16226627 chr15:75307476 SCAMP5 0.51 8.81 0.43 6.34e-17 Lung cancer; LIHC cis rs2637266 1.000 rs1907305 chr10:78339512 C/G cg18941641 chr10:78392320 NA 0.29 6.19 0.32 1.74e-9 Pulmonary function; LIHC cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg13395646 chr4:1353034 KIAA1530 -0.64 -9.13 -0.44 5.98e-18 Obesity-related traits; LIHC cis rs11252926 0.550 rs11252134 chr10:442599 G/A cg16346588 chr10:242978 ZMYND11 0.38 5.84 0.3 1.22e-8 Psychosis in Alzheimer's disease; LIHC cis rs13118159 1.000 rs13118159 chr4:1365127 A/G cg20887711 chr4:1340912 KIAA1530 0.48 5.87 0.3 1.05e-8 Longevity; LIHC cis rs708547 0.723 rs35982175 chr4:57841365 C/T cg25525207 chr4:57843836 C4orf14;POLR2B -0.41 -6.42 -0.33 4.67e-10 Response to bleomycin (chromatid breaks); LIHC cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.41 0.52 9.38e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2067615 0.524 rs10778499 chr12:107068387 C/T cg15890332 chr12:107067104 RFX4 0.27 6.46 0.33 3.62e-10 Heart rate; LIHC cis rs9633740 1.000 rs7922621 chr10:82251544 C/A cg01528321 chr10:82214614 TSPAN14 0.93 12.13 0.55 2.12e-28 Post bronchodilator FEV1; LIHC cis rs9880406 0.833 rs938389 chr3:126058762 C/T cg15490784 chr3:126061950 KLF15 0.41 5.78 0.3 1.68e-8 Macular telangiectasia type 2; LIHC cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg05590025 chr7:65112418 INTS4L2 -0.62 -6.7 -0.34 8.76e-11 Diabetic kidney disease; LIHC trans rs1005277 0.540 rs289638 chr10:37923731 G/A cg17830980 chr10:43048298 ZNF37B -0.43 -8.3 -0.41 2.46e-15 Extrinsic epigenetic age acceleration; LIHC cis rs61990749 0.597 rs176971 chr14:78191599 T/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.71 -0.38 1.37e-13 Fibroblast growth factor basic levels; LIHC cis rs758324 0.947 rs6596040 chr5:131198777 C/T cg06307176 chr5:131281290 NA 0.4 5.81 0.3 1.42e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg10802521 chr3:52805072 NEK4 -0.44 -7.33 -0.37 1.71e-12 Bipolar disorder; LIHC cis rs365132 1.000 rs402511 chr5:176434440 G/A cg16309518 chr5:176445507 NA -0.58 -11.56 -0.53 2.58e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs11628318 0.515 rs4906245 chr14:103088182 G/C cg12046867 chr14:103022105 NA -0.37 -5.72 -0.3 2.28e-8 Platelet count; LIHC cis rs4728302 0.608 rs10254118 chr7:133158353 T/A cg10665199 chr7:133106180 EXOC4 0.53 8.79 0.43 7.35e-17 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7659604 0.540 rs7699289 chr4:122671553 G/A cg19671926 chr4:122722719 EXOSC9 0.49 7.16 0.36 4.87e-12 Type 2 diabetes; LIHC cis rs3820068 0.705 rs4646092 chr1:15821673 C/T cg17385448 chr1:15911702 AGMAT 0.37 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs3736594 0.559 rs1919129 chr2:27818721 C/G cg27432699 chr2:27873401 GPN1 0.45 6.76 0.34 5.98e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs1559088 0.576 rs10407255 chr19:33581150 A/G cg17764715 chr19:33622953 WDR88 -0.61 -8.57 -0.42 3.56e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.92 9.39 0.45 8.53e-19 Platelet count; LIHC cis rs9486719 0.895 rs12195315 chr6:96905711 T/G cg06623918 chr6:96969491 KIAA0776 -0.71 -7.13 -0.36 6.08e-12 Migraine;Coronary artery disease; LIHC cis rs10876993 0.890 rs1678516 chr12:58047458 G/A cg15848620 chr12:58087721 OS9 -0.55 -7.49 -0.38 5.89e-13 Celiac disease or Rheumatoid arthritis; LIHC trans rs2270927 1.000 rs13174383 chr5:75580416 T/G cg13563193 chr19:33072644 PDCD5 0.98 10.2 0.48 1.72e-21 Mean corpuscular volume; LIHC cis rs57244997 0.725 rs7746243 chr6:162436437 G/C cg17173639 chr6:162384350 PARK2 -0.49 -6.42 -0.33 4.48e-10 Mosquito bite size; LIHC cis rs909002 0.962 rs1474181 chr1:32136610 C/G cg13919466 chr1:32135498 COL16A1 -0.36 -6.93 -0.35 2.14e-11 Intelligence (multi-trait analysis); LIHC cis rs6964587 0.933 rs10271174 chr7:91785970 A/G cg17063962 chr7:91808500 NA 1.01 20.73 0.75 2.04e-62 Breast cancer; LIHC cis rs9399135 0.967 rs4896122 chr6:135295081 T/C cg22676075 chr6:135203613 NA 0.4 6.47 0.33 3.49e-10 Red blood cell count; LIHC cis rs763121 0.819 rs8137829 chr22:39061030 G/A cg14440974 chr22:39074834 NA -0.43 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC cis rs12477438 0.765 rs10181344 chr2:99692829 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.7 -0.5 3.03e-23 Chronic sinus infection; LIHC cis rs7584330 0.554 rs62186170 chr2:238425883 C/T cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs11673344 0.764 rs474017 chr19:37454119 A/G cg27390819 chr19:37464633 NA -0.53 -6.38 -0.33 5.61e-10 Obesity-related traits; LIHC cis rs3741798 0.614 rs61922044 chr12:12490914 G/A cg08615371 chr12:12503544 MANSC1 0.93 7.5 0.38 5.39e-13 Cerebrospinal fluid biomarker levels; LIHC cis rs11690935 0.571 rs1008151 chr2:172912098 G/A cg13550731 chr2:172543902 DYNC1I2 0.44 6.3 0.32 9.38e-10 Schizophrenia; LIHC cis rs921968 0.643 rs500317 chr2:219432953 G/C cg02985541 chr2:219472218 PLCD4 0.44 8.46 0.42 7.9e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs986417 0.818 rs767603 chr14:61098683 T/C cg27398547 chr14:60952738 C14orf39 0.66 7.32 0.37 1.81e-12 Gut microbiota (bacterial taxa); LIHC cis rs9916302 0.904 rs2338797 chr17:37548241 G/A cg03013999 chr17:37608204 MED1 -0.36 -5.97 -0.31 5.89e-9 Glomerular filtration rate (creatinine); LIHC cis rs12986413 0.967 rs2108524 chr19:2170764 A/G cg09261902 chr19:2140048 AP3D1 0.38 6.34 0.32 7.28e-10 Height; LIHC cis rs16912285 0.535 rs7936178 chr11:24252515 G/T ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.24e-27 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs7412746 0.597 rs868751 chr1:150669414 T/G cg13175981 chr1:150552382 MCL1 -0.43 -5.97 -0.31 5.98e-9 Melanoma; LIHC trans rs1552244 0.572 rs17032440 chr3:10169819 A/C cg26113512 chr3:38035601 VILL 0.55 6.41 0.33 4.8e-10 Alzheimer's disease; LIHC cis rs801193 0.935 rs2659899 chr7:66186721 A/G cg18876405 chr7:65276391 NA 0.43 7.48 0.37 6.44e-13 Aortic root size; LIHC cis rs34172651 0.517 rs11862923 chr16:24767303 G/T cg04756594 chr16:24857601 SLC5A11 0.61 9.31 0.45 1.58e-18 Intelligence (multi-trait analysis); LIHC cis rs2274273 0.837 rs7148171 chr14:55770744 G/C cg01864836 chr14:55583639 NA -0.4 -7.45 -0.37 7.51e-13 Protein biomarker; LIHC cis rs17286411 0.750 rs2288030 chr16:71914107 G/A cg03805757 chr16:71968109 PKD1L3 0.41 5.85 0.3 1.13e-8 Blood protein levels; LIHC cis rs611744 0.967 rs636399 chr8:109235569 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs1419980 0.730 rs1833148 chr12:7774680 C/T cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02038173 chr21:34852701 TMEM50B 0.48 6.42 0.33 4.67e-10 Lung function (FEV1/FVC); LIHC cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg06481639 chr22:41940642 POLR3H -0.7 -7.11 -0.36 6.64e-12 Vitiligo; LIHC cis rs3789045 0.774 rs12031912 chr1:204476113 A/G cg17419461 chr1:204415978 PIK3C2B -0.39 -5.93 -0.31 7.24e-9 Educational attainment (college completion); LIHC cis rs644799 0.763 rs2950521 chr11:95536870 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.7 10.14 0.48 2.71e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs17685 0.712 rs1859794 chr7:75821544 G/A cg19862616 chr7:65841803 NCRNA00174 0.89 18.14 0.7 5.62e-52 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg16103275 chr6:290800 DUSP22 -0.49 -6.48 -0.33 3.16e-10 Menopause (age at onset); LIHC cis rs6942756 1.000 rs6974155 chr7:128914545 C/G cg02491457 chr7:128862824 NA -0.67 -10.58 -0.5 8.2000000000000006e-23 White matter hyperintensity burden; LIHC cis rs17106184 1.000 rs12083647 chr1:51314649 A/G cg07174182 chr1:51127561 FAF1 -0.62 -6.62 -0.34 1.43e-10 Type 2 diabetes; LIHC cis rs763121 0.853 rs11704021 chr22:39074716 G/A cg06022373 chr22:39101656 GTPBP1 0.65 11.41 0.52 9.35e-26 Menopause (age at onset); LIHC cis rs7193541 0.965 rs28616016 chr16:74676964 T/C cg01733217 chr16:74700730 RFWD3 0.56 10.98 0.51 3.03e-24 Multiple myeloma; LIHC cis rs4808199 0.948 rs968525 chr19:19459215 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.57 8.32 0.41 2.07e-15 Nonalcoholic fatty liver disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26105702 chr2:209120195 IDH1 -0.43 -6.04 -0.31 4.04e-9 Pancreatic cancer; LIHC cis rs754466 0.580 rs12354903 chr10:79536465 T/C cg17075019 chr10:79541650 NA -0.8 -12.49 -0.56 9.23e-30 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1538970 0.924 rs1826691 chr1:45881262 A/G cg05343316 chr1:45956843 TESK2 -0.56 -7.93 -0.39 3.2e-14 Platelet count; LIHC cis rs17401966 1.000 rs17401966 chr1:10385471 C/T cg19773385 chr1:10388646 KIF1B 0.47 8.1 0.4 9.64e-15 Hepatocellular carcinoma; LIHC cis rs9473924 0.542 rs9473928 chr6:50842003 G/A cg14470998 chr6:50812995 TFAP2B 0.93 10.68 0.5 3.66e-23 Body mass index; LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg00656387 chr3:40428638 ENTPD3 0.5 8.42 0.41 1.07e-15 Renal cell carcinoma; LIHC cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.61e-21 Intelligence (multi-trait analysis); LIHC cis rs2749592 0.611 rs176888 chr10:38406161 C/A cg00409905 chr10:38381863 ZNF37A -0.52 -8.36 -0.41 1.58e-15 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7098414 0.511 rs10749592 chr10:82150891 C/T cg01528321 chr10:82214614 TSPAN14 0.41 6.32 0.32 8.35e-10 Post bronchodilator FEV1; LIHC cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg10360323 chr17:41437877 NA 0.4 5.95 0.31 6.7e-9 Menopause (age at onset); LIHC cis rs876084 0.505 rs7459865 chr8:121115611 A/T cg06265175 chr8:121136014 COL14A1 0.44 7.09 0.36 7.9e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs546131 0.614 rs35953213 chr11:34848769 A/G cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.55 -0.33 2.17e-10 Lung disease severity in cystic fibrosis; LIHC cis rs2997447 0.761 rs17184891 chr1:26447557 A/T cg19633962 chr1:26362018 EXTL1 -0.64 -5.88 -0.3 9.64e-9 QRS complex (12-leadsum); LIHC cis rs6120849 0.754 rs1885117 chr20:33600740 C/T cg24642439 chr20:33292090 TP53INP2 0.65 7.2 0.36 3.91e-12 Protein C levels; LIHC cis rs1144333 1.000 rs5745542 chr1:76365073 C/G cg10523679 chr1:76189770 ACADM 0.45 6.47 0.33 3.38e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs7248779 0.532 rs10153475 chr19:2413961 G/C cg22729335 chr19:2427816 TIMM13 1.1 23.58 0.79 1.08e-73 Cortisol levels (saliva); LIHC trans rs5756813 0.754 rs8137848 chr22:38185994 T/G cg19894588 chr14:64061835 NA -0.65 -9.18 -0.44 4.16e-18 Optic cup area;Vertical cup-disc ratio; LIHC cis rs6831352 0.840 rs35073321 chr4:100053276 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs2243480 1.000 rs160643 chr7:65558222 C/T cg05590025 chr7:65112418 INTS4L2 -0.54 -6.24 -0.32 1.28e-9 Diabetic kidney disease; LIHC cis rs6726292 0.500 rs1822617 chr2:55227231 C/G cg09592903 chr2:55203963 RTN4 -0.48 -7.43 -0.37 8.65e-13 Obesity (extreme); LIHC cis rs9929218 1.000 rs11865026 chr16:68774283 A/G cg01231543 chr16:68741748 NA 0.39 6.21 0.32 1.54e-9 Colorectal cancer; LIHC cis rs7945718 0.621 rs10831887 chr11:12665436 A/C cg25843174 chr11:12811716 TEAD1 0.33 7.71 0.38 1.41e-13 Educational attainment (years of education); LIHC cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.49 0.46 4e-19 Bipolar disorder; LIHC cis rs644799 0.526 rs534973 chr11:95633624 A/T cg03916912 chr11:95522834 CEP57;FAM76B 0.57 8.9 0.43 3.36e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs875971 1.000 rs6958271 chr7:65979331 A/C cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.75e-9 Aortic root size; LIHC cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg19318889 chr4:1322082 MAEA -0.48 -7.99 -0.4 2.05e-14 Obesity-related traits; LIHC cis rs611744 0.647 rs2594358 chr8:109256018 A/G cg21045802 chr8:109455806 TTC35 0.6 10.58 0.5 7.9e-23 Dupuytren's disease; LIHC cis rs7937682 0.575 rs7124696 chr11:111747297 A/G cg09085632 chr11:111637200 PPP2R1B 0.96 13.91 0.6 3.63e-35 Primary sclerosing cholangitis; LIHC cis rs9611565 0.592 rs28750375 chr22:41990644 A/C cg06634786 chr22:41940651 POLR3H -0.56 -5.92 -0.3 7.82e-9 Vitiligo; LIHC cis rs801193 1.000 rs2286684 chr7:66129830 G/T cg00343986 chr7:65444356 GUSB -0.39 -5.84 -0.3 1.2e-8 Aortic root size; LIHC cis rs2303759 0.626 rs12982246 chr19:49801169 A/G cg22590775 chr19:49891494 CCDC155 0.48 7.7 0.38 1.53e-13 Multiple sclerosis; LIHC cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg12310025 chr6:25882481 NA -0.61 -7.78 -0.39 8.75e-14 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.744 rs11168870 chr12:37973333 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs4820294 0.547 rs62236743 chr22:38096053 T/C cg00292662 chr22:38071168 LGALS1 0.65 8.48 0.42 6.78e-16 Fat distribution (HIV); LIHC cis rs11758351 0.660 rs55643278 chr6:26222888 C/A cg03854865 chr6:26224070 HIST1H3E 0.59 6.42 0.33 4.67e-10 Gout;Renal underexcretion gout; LIHC cis rs12142240 0.698 rs3991877 chr1:46853749 C/A cg00530320 chr1:46809349 NSUN4 0.53 5.77 0.3 1.82e-8 Menopause (age at onset); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg22867288 chr6:57086716 RAB23 0.42 6.13 0.31 2.48e-9 Migraine with aura; LIHC trans rs4566357 0.615 rs12618793 chr2:227909552 T/C cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.6e-9 Coronary artery disease; LIHC cis rs10464366 0.746 rs34792397 chr7:39146331 G/A cg10621924 chr7:39171070 POU6F2 0.39 6.09 0.31 2.98e-9 IgG glycosylation; LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg04267008 chr7:1944627 MAD1L1 0.61 9.81 0.47 3.47e-20 Bipolar disorder and schizophrenia; LIHC cis rs2836974 0.666 rs1888487 chr21:40683259 A/G cg11890956 chr21:40555474 PSMG1 -0.5 -7.82 -0.39 6.49e-14 Cognitive function; LIHC cis rs3020736 0.500 rs4147638 chr22:42487900 G/A cg04733989 chr22:42467013 NAGA -0.67 -9.64 -0.46 1.33e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg11502198 chr6:26597334 ABT1 0.61 9.76 0.47 5.35e-20 Intelligence (multi-trait analysis); LIHC cis rs11676348 0.811 rs4674255 chr2:218987325 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.45 -6.22 -0.32 1.45e-9 Ulcerative colitis; LIHC cis rs9649213 0.555 rs6955259 chr7:97892356 T/A cg08684580 chr7:98029266 BAIAP2L1 -0.4 -6.1 -0.31 2.85e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs6461049 0.734 rs1558465 chr7:2151398 G/C cg21782813 chr7:2030301 MAD1L1 0.36 6.15 0.32 2.12e-9 Schizophrenia; LIHC cis rs3540 0.553 rs4031431 chr15:90990782 G/T cg22089800 chr15:90895588 ZNF774 0.58 7.99 0.4 2.1e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs919433 0.783 rs788014 chr2:198228997 G/A cg10820045 chr2:198174542 NA 0.55 8.78 0.43 7.88e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9611565 0.559 rs132771 chr22:42025350 A/G cg03806693 chr22:41940476 POLR3H 0.98 10.67 0.5 4.01e-23 Vitiligo; LIHC cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.31 0.52 2.05e-25 Colorectal cancer; LIHC cis rs2302190 0.882 rs11650105 chr17:56588072 C/T cg12560992 chr17:57184187 TRIM37 0.7 8.9 0.43 3.38e-17 Vitamin D levels; LIHC trans rs4718428 0.672 rs36038499 chr7:66289615 A/G cg10756647 chr7:56101905 PSPH 0.63 8.68 0.42 1.62e-16 Corneal structure; LIHC cis rs793571 0.590 rs474875 chr15:59086703 A/C cg05156742 chr15:59063176 FAM63B 0.43 7.09 0.36 7.54e-12 Schizophrenia; LIHC cis rs3736485 0.966 rs2305708 chr15:51909960 C/T cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.56e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs116095464 0.558 rs6879656 chr5:264428 T/C cg22496380 chr5:211416 CCDC127 -1.12 -11.01 -0.51 2.51e-24 Breast cancer; LIHC cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg11764359 chr7:65958608 NA -0.57 -5.92 -0.31 7.72e-9 Diabetic kidney disease; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg26338869 chr17:61819248 STRADA 0.52 6.99 0.35 1.46e-11 Height; LIHC cis rs2663905 1.000 rs2663905 chr15:81359137 G/A cg09888468 chr15:81410853 NA -0.43 -7.08 -0.36 8.26e-12 QT interval (drug interaction); LIHC cis rs1577917 0.538 rs6454483 chr6:86418283 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.32 6.0 0.31 5.07e-9 Response to antipsychotic treatment; LIHC cis rs4555082 1.000 rs7146643 chr14:105757392 A/G cg13114125 chr14:105738426 BRF1 -0.67 -9.2 -0.45 3.5e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs611744 0.647 rs676654 chr8:109242303 A/G cg18478394 chr8:109455254 TTC35 0.41 6.99 0.35 1.44e-11 Dupuytren's disease; LIHC cis rs780094 0.544 rs2303370 chr2:27651375 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.77 -0.34 5.78e-11 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs2820292 0.967 rs2820290 chr1:201783682 A/G cg11586189 chr1:201857591 SHISA4 0.39 5.76 0.3 1.89e-8 Waist circumference;Body mass index (joint analysis main effects and smoking interaction);Body mass index;BMI in non-smokers;BMI (adjusted for smoking behaviour); LIHC cis rs1799949 1.000 rs2298862 chr17:41176688 T/C cg23758822 chr17:41437982 NA 0.93 17.2 0.68 3.13e-48 Menopause (age at onset); LIHC cis rs965469 0.779 rs6051752 chr20:3310452 C/T cg25506879 chr20:3388711 C20orf194 -0.5 -6.14 -0.32 2.28e-9 IFN-related cytopenia; LIHC trans rs57221529 0.545 rs55955015 chr5:575182 A/G cg25482853 chr8:67687455 SGK3 0.62 6.24 0.32 1.28e-9 Lung disease severity in cystic fibrosis; LIHC cis rs7100689 0.646 rs1934693 chr10:82125650 T/C cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs11212737 0.765 rs2128243 chr11:108509754 A/G cg22776369 chr11:108536276 DDX10 0.37 6.04 0.31 4.05e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs9733 0.744 rs3754211 chr1:150951857 G/A cg13175981 chr1:150552382 MCL1 -0.47 -6.67 -0.34 1.03e-10 Tonsillectomy; LIHC cis rs2180341 1.000 rs9285460 chr6:127640190 A/G cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg10295955 chr4:187884368 NA 0.94 21.3 0.76 1.11e-64 Lobe attachment (rater-scored or self-reported); LIHC cis rs12477438 0.520 rs1133978 chr2:99741964 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs79387448 0.745 rs9677607 chr2:103149520 A/T cg09003973 chr2:102972529 NA 0.85 7.47 0.37 6.82e-13 Gut microbiota (bacterial taxa); LIHC cis rs738322 0.753 rs2267372 chr22:38598234 A/G cg25457927 chr22:38595422 NA 0.42 10.58 0.5 7.93e-23 Cutaneous nevi; LIHC trans rs4604234 0.803 rs76568328 chr6:80977101 T/C cg08069338 chr6:160207898 SNORA29;TCP1 0.63 6.16 0.32 2.07e-9 Cancer; LIHC cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg13047869 chr3:10149882 C3orf24 0.41 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs7100689 0.622 rs4536152 chr10:82119242 C/T cg00277334 chr10:82204260 NA -0.53 -6.63 -0.34 1.29e-10 Post bronchodilator FEV1; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg18538332 chr22:24372958 LOC391322 -0.57 -7.94 -0.39 2.99e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17685 0.884 rs3823882 chr7:75631913 T/C cg01364799 chr7:75623366 TMEM120A 0.46 6.96 0.35 1.7e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs68170813 0.559 rs1548524 chr7:106944563 G/T cg02696742 chr7:106810147 HBP1 0.5 5.78 0.3 1.69e-8 Coronary artery disease; LIHC cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.01 -0.44 1.43e-17 Bipolar disorder; LIHC cis rs3780378 0.935 rs2149560 chr9:5082106 G/T cg02405213 chr9:5042618 JAK2 -0.51 -8.77 -0.43 8.67e-17 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs743757 0.878 rs12494849 chr3:50524558 C/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.29 0.37 2.16e-12 Diastolic blood pressure; LIHC cis rs875971 0.638 rs3898855 chr7:66036398 G/C cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs7089973 0.604 rs8181444 chr10:116588981 C/T cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9911578 0.967 rs7503190 chr17:57184162 A/C cg12560992 chr17:57184187 TRIM37 0.97 17.94 0.7 3.35e-51 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.894 rs2121661 chr2:61561658 A/G cg15711740 chr2:61764176 XPO1 0.43 5.86 0.3 1.08e-8 Tuberculosis; LIHC cis rs140364877 1 rs140364877 chr7:1885178 C/T cg04267008 chr7:1944627 MAD1L1 -0.58 -8.97 -0.44 1.96e-17 Autism spectrum disorder or schizophrenia; LIHC cis rs41271473 0.526 rs56043220 chr1:228783474 G/C cg10167378 chr1:228756711 NA 0.59 5.88 0.3 9.82e-9 Chronic lymphocytic leukemia; LIHC trans rs9951602 0.512 rs6506874 chr18:76653467 G/T cg02800362 chr5:177631904 HNRNPAB 0.66 10.52 0.49 1.33e-22 Obesity-related traits; LIHC cis rs1278769 0.735 rs9577395 chr13:113534984 C/G cg00823993 chr13:113535758 ATP11A 0.61 7.33 0.37 1.71e-12 Interstitial lung disease; LIHC cis rs11626933 1.000 rs11626933 chr14:90754311 A/G cg07150772 chr14:90864620 CALM1 -0.42 -5.88 -0.3 9.62e-9 Gut microbiota (bacterial taxa); LIHC cis rs738321 0.757 rs3788534 chr22:38533971 A/T cg25457927 chr22:38595422 NA -0.29 -6.73 -0.34 7.2e-11 Breast cancer; LIHC cis rs3748682 0.821 rs12030690 chr1:38258007 G/C cg12658694 chr1:38397304 INPP5B 0.48 6.72 0.34 7.72e-11 Hypothyroidism; LIHC trans rs2727020 0.513 rs10839307 chr11:49609843 A/C cg15704280 chr7:45808275 SEPT13 -1.02 -22.16 -0.77 4.26e-68 Coronary artery disease; LIHC cis rs10744422 1.000 rs2061101 chr12:123348925 C/A cg25930673 chr12:123319894 HIP1R -0.79 -9.13 -0.44 6.01e-18 Schizophrenia; LIHC trans rs9929218 0.871 rs1862748 chr16:68832943 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.56 -8.39 -0.41 1.33e-15 Colorectal cancer; LIHC cis rs34779708 0.898 rs4934695 chr10:35280605 C/T cg03585969 chr10:35415529 CREM 0.87 13.04 0.58 7.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC trans rs61931739 0.534 rs4547187 chr12:34041259 T/C cg26384229 chr12:38710491 ALG10B 0.43 6.08 0.31 3.16e-9 Morning vs. evening chronotype; LIHC cis rs8081395 0.580 rs180515 chr17:58024275 A/G cg02344993 chr17:57696989 CLTC 0.45 7.51 0.38 5.31e-13 White blood cell count; LIHC cis rs875971 0.862 rs801203 chr7:66023012 A/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC cis rs17685 0.712 rs1637049 chr7:75729975 C/G cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.33e-16 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01566283 chr6:28109239 ZNF192 0.36 6.64 0.34 1.26e-10 Calcium levels; LIHC cis rs7917772 0.503 rs2031602 chr10:104307955 G/C cg22532475 chr10:104410764 TRIM8 -0.3 -5.94 -0.31 6.86e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11588062 0.628 rs11211270 chr1:46838986 C/T cg06787764 chr1:46668870 C1orf190;POMGNT1 0.45 6.9 0.35 2.5e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs34172651 0.837 rs1978451 chr16:24818286 C/G cg00152838 chr16:24741724 TNRC6A -0.46 -6.16 -0.32 2.1e-9 Intelligence (multi-trait analysis); LIHC cis rs116095464 0.558 rs6866632 chr5:264429 C/G cg22496380 chr5:211416 CCDC127 -1.1 -11.22 -0.52 4.28e-25 Breast cancer; LIHC cis rs17125944 1.000 rs17125924 chr14:53391680 A/G cg00686598 chr14:53173677 PSMC6 0.77 8.33 0.41 2.02e-15 Alzheimer's disease (late onset); LIHC cis rs3862260 0.509 rs10754416 chr1:120163531 A/G cg16322792 chr1:120165303 ZNF697 0.51 9.33 0.45 1.34e-18 Systemic lupus erythematosus; LIHC cis rs7520050 0.751 rs2991975 chr1:46024526 A/G cg03146154 chr1:46216737 IPP -0.46 -7.26 -0.37 2.66e-12 Red blood cell count;Reticulocyte count; LIHC cis rs5753618 0.561 rs4603880 chr22:31744721 T/C cg07713946 chr22:31675144 LIMK2 0.42 7.53 0.38 4.67e-13 Colorectal cancer; LIHC cis rs921968 0.643 rs585859 chr2:219383121 C/T cg17980119 chr2:219472607 PLCD4 0.35 6.02 0.31 4.62e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07874155 chr5:138089656 CTNNA1 0.46 6.68 0.34 9.93e-11 Pancreatic cancer; LIHC cis rs992157 0.798 rs2382817 chr2:219151218 A/C cg00012203 chr2:219082015 ARPC2 0.84 13.58 0.59 6.56e-34 Colorectal cancer; LIHC cis rs9911578 0.933 rs2531726 chr17:56522533 C/T cg12560992 chr17:57184187 TRIM37 -0.9 -15.76 -0.65 1.88e-42 Intelligence (multi-trait analysis); LIHC cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg18305652 chr10:134549665 INPP5A 0.51 8.25 0.41 3.56e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12586317 0.586 rs74243591 chr14:35520917 C/T cg05294307 chr14:35346193 BAZ1A -0.48 -6.96 -0.35 1.78e-11 Psoriasis; LIHC cis rs3814244 0.528 rs7952790 chr12:68406452 C/T cg15249341 chr12:68405565 NA -0.31 -6.12 -0.31 2.59e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs2727020 0.553 rs3907576 chr11:49536639 A/C cg03929089 chr4:120376271 NA -0.88 -16.66 -0.67 4.74e-46 Coronary artery disease; LIHC cis rs853679 0.542 rs9393892 chr6:28081394 A/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs2180341 0.814 rs6905553 chr6:127727407 A/G cg24812749 chr6:127587940 RNF146 0.79 12.59 0.56 4.04e-30 Breast cancer; LIHC trans rs4843747 0.636 rs4075597 chr16:88107590 C/A cg09572067 chr16:29127029 RRN3P2 0.5 7.93 0.39 3.09e-14 Menopause (age at onset); LIHC cis rs16912285 0.688 rs7109312 chr11:24338974 G/A ch.11.24196551F chr11:24239977 NA 0.69 7.7 0.38 1.45e-13 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs2153535 0.580 rs2183112 chr6:8528212 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.5 0.53 4.42e-26 Motion sickness; LIHC cis rs16858210 0.913 rs1879255 chr3:183609445 C/A cg25686905 chr3:183603175 PARL -0.49 -9.09 -0.44 8.39e-18 Menopause (age at onset); LIHC cis rs2455799 0.574 rs2455801 chr3:15701857 C/T cg16303742 chr3:15540471 COLQ -0.34 -5.83 -0.3 1.28e-8 Mean platelet volume; LIHC cis rs796364 0.806 rs11679658 chr2:200923081 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs4474465 1.000 rs4474465 chr11:78204380 C/T cg27205649 chr11:78285834 NARS2 0.38 5.71 0.3 2.4e-8 Alzheimer's disease (survival time); LIHC cis rs6430585 0.528 rs309122 chr2:136761853 A/G cg07169764 chr2:136633963 MCM6 0.96 14.78 0.62 1.46e-38 Corneal structure; LIHC cis rs16828019 0.777 rs12023079 chr1:41470111 G/A cg03387723 chr1:41708464 SCMH1 -0.45 -6.91 -0.35 2.37e-11 Intelligence (multi-trait analysis); LIHC cis rs6456156 0.586 rs6909180 chr6:167460537 A/G cg07741184 chr6:167504864 NA 0.29 6.75 0.34 6.23e-11 Primary biliary cholangitis; LIHC cis rs2153535 0.601 rs969420 chr6:8451966 T/A cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC trans rs2739330 0.587 rs4820571 chr22:24242973 A/G cg06437703 chr8:37914619 EIF4EBP1 -0.54 -7.88 -0.39 4.41e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs1814175 0.626 rs1722008 chr11:49897676 A/T cg03929089 chr4:120376271 NA -0.89 -17.75 -0.69 2.04e-50 Height; LIHC cis rs13161895 1.000 rs35973843 chr5:179466502 T/C cg02702477 chr5:179499311 RNF130 0.8 11.17 0.52 6.67e-25 LDL cholesterol; LIHC cis rs2749592 0.505 rs7915670 chr10:37870212 T/C cg00409905 chr10:38381863 ZNF37A 0.51 8.63 0.42 2.33e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9534288 0.830 rs3783202 chr13:46631869 G/A cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg02869306 chr7:64672164 INTS4L1 -0.29 -6.41 -0.33 4.84e-10 Calcium levels; LIHC cis rs1059312 0.808 rs900982 chr12:129304369 G/A cg09035930 chr12:129282057 SLC15A4 0.61 11.32 0.52 1.86e-25 Systemic lupus erythematosus; LIHC cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg18305652 chr10:134549665 INPP5A 0.43 6.31 0.32 8.62e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2276314 1.000 rs4799832 chr18:33559646 T/C cg05985134 chr18:33552581 C18orf21 0.49 5.81 0.3 1.44e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs8058578 1.000 rs56656810 chr16:30788759 C/A cg02466173 chr16:30829666 NA -0.44 -6.88 -0.35 2.84e-11 Multiple myeloma; LIHC cis rs34779708 0.898 rs11595898 chr10:35326263 T/C cg03585969 chr10:35415529 CREM 0.84 12.76 0.57 9.4e-31 Inflammatory bowel disease;Crohn's disease; LIHC trans rs867371 0.892 rs4344697 chr15:82545214 A/T cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.06 -0.36 9.2e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs6951245 0.554 rs75075857 chr7:1140298 C/T cg13565492 chr6:43139072 SRF -0.78 -7.27 -0.37 2.4e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618501 0.633 rs2526748 chr3:50080439 A/G cg21467203 chr3:49911342 NA 0.43 7.65 0.38 2.09e-13 Intelligence (multi-trait analysis); LIHC cis rs1866706 1.000 rs6486066 chr11:12871127 A/G cg25843174 chr11:12811716 TEAD1 0.29 6.21 0.32 1.55e-9 Intelligence (multi-trait analysis); LIHC cis rs79976124 0.800 rs10944857 chr6:66637078 C/T cg07460842 chr6:66804631 NA 0.66 7.1 0.36 7.33e-12 Type 2 diabetes; LIHC cis rs4638749 0.677 rs12712017 chr2:108843556 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -5.97 -0.31 6.06e-9 Blood pressure; LIHC cis rs1799949 0.965 rs9911630 chr17:41188342 A/G cg25072359 chr17:41440525 NA 0.37 6.01 0.31 4.84e-9 Menopause (age at onset); LIHC cis rs11758351 1.000 rs17598927 chr6:26184640 C/G cg01420254 chr6:26195488 NA -0.53 -5.76 -0.3 1.83e-8 Gout;Renal underexcretion gout; LIHC cis rs17102423 0.755 rs12880781 chr14:65576257 C/T cg11161011 chr14:65562177 MAX -0.59 -8.24 -0.41 3.65e-15 Obesity-related traits; LIHC cis rs765787 0.530 rs2668737 chr15:45522799 C/T cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.88e-10 Uric acid levels; LIHC cis rs4727027 0.866 rs1405124 chr7:148779618 C/T cg23583168 chr7:148888333 NA -0.67 -9.64 -0.46 1.31e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2380220 0.678 rs4308568 chr6:96009525 A/C cg04719120 chr6:96025338 MANEA -0.57 -7.19 -0.36 4.02e-12 Behavioural disinhibition (generation interaction); LIHC cis rs9921222 0.565 rs1805105 chr16:396264 A/G cg12437481 chr16:420112 MRPL28 -0.51 -7.52 -0.38 5e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs11098499 0.909 rs28884220 chr4:120307211 A/G cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.38e-26 Corneal astigmatism; LIHC cis rs11122272 0.735 rs2491416 chr1:231547335 T/C cg06096015 chr1:231504339 EGLN1 -0.51 -9.5 -0.46 3.67e-19 Hemoglobin concentration; LIHC trans rs61931739 0.500 rs10844829 chr12:34304916 G/T cg26384229 chr12:38710491 ALG10B 0.58 7.54 0.38 4.35e-13 Morning vs. evening chronotype; LIHC trans rs116095464 0.558 rs62347678 chr5:227496 A/G cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs2404602 0.692 rs59088060 chr15:76859974 T/C cg03037974 chr15:76606532 NA 0.74 14.44 0.62 3.06e-37 Blood metabolite levels; LIHC cis rs12477438 0.501 rs11688004 chr2:99735052 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.13 0.61 5.14e-36 Chronic sinus infection; LIHC cis rs4930103 0.590 rs3809101 chr11:1967271 C/T cg23202291 chr11:1979235 NA 0.52 6.43 0.33 4.4e-10 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg25072359 chr17:41440525 NA 0.39 6.16 0.32 2e-9 Menopause (age at onset); LIHC cis rs6500602 0.702 rs2058812 chr16:4524443 C/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 6.21 0.32 1.56e-9 Schizophrenia; LIHC cis rs3008870 0.958 rs34367328 chr1:67445321 T/C cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs344364 0.511 rs56077812 chr16:1948870 T/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs7552404 0.590 rs1565717 chr1:76320441 T/C cg03433033 chr1:76189801 ACADM -0.55 -6.92 -0.35 2.3e-11 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09417774 chr12:112037791 ATXN2 0.48 6.31 0.32 8.54e-10 Pancreatic cancer; LIHC cis rs903552 0.935 rs4965387 chr15:102003209 G/A cg06707286 chr15:102010195 PCSK6 -0.45 -6.42 -0.33 4.43e-10 Diabetic kidney disease; LIHC cis rs8014204 1.000 rs8014374 chr14:75322914 G/A cg08847533 chr14:75593920 NEK9 -0.35 -5.73 -0.3 2.21e-8 Caffeine consumption; LIHC cis rs910316 0.737 rs175065 chr14:75494983 T/C cg08847533 chr14:75593920 NEK9 -0.89 -18.09 -0.7 8.17e-52 Height; LIHC cis rs765787 0.530 rs2458224 chr15:45522130 T/C cg24006582 chr15:45444508 DUOX1 -0.5 -7.26 -0.37 2.56e-12 Uric acid levels; LIHC cis rs1185460 0.565 rs2276060 chr11:118919132 G/A cg01677386 chr11:118938358 VPS11 0.43 5.75 0.3 1.97e-8 Coronary artery disease; LIHC trans rs5756813 0.727 rs4821703 chr22:38136676 C/T cg19894588 chr14:64061835 NA -0.6 -8.02 -0.4 1.65e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs748404 0.690 rs2467737 chr15:43737188 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.35 0.37 1.48e-12 Lung cancer; LIHC trans rs36715 0.953 rs36700 chr5:127551273 A/G cg16011800 chr17:1958478 HIC1 -0.41 -6.11 -0.31 2.74e-9 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05902063 chr12:96794315 CDK17 -0.48 -6.63 -0.34 1.33e-10 Pancreatic cancer; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.62 -8.89 -0.43 3.49e-17 Lymphocyte counts; LIHC cis rs68170813 0.559 rs17350182 chr7:106909637 T/A cg02696742 chr7:106810147 HBP1 -0.51 -5.9 -0.3 8.7e-9 Coronary artery disease; LIHC cis rs7772486 0.790 rs6926657 chr6:146255794 G/A cg05347473 chr6:146136440 FBXO30 -0.36 -5.83 -0.3 1.29e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs11588062 1.000 rs11588062 chr1:46779764 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.59 9.55 0.46 2.51e-19 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg21821726 chr22:50170866 BRD1 0.39 6.22 0.32 1.44e-9 Bilirubin levels; LIHC cis rs11625487 0.957 rs7156032 chr14:77951364 G/A cg20045696 chr14:77926864 AHSA1 -0.82 -7.71 -0.38 1.41e-13 Neutrophil percentage of white cells;Sum neutrophil eosinophil counts;Neutrophil count; LIHC cis rs7903847 0.642 rs11189200 chr10:99156273 C/G cg20016023 chr10:99160130 RRP12 -0.43 -6.69 -0.34 8.95e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs240764 0.658 rs12174806 chr6:101219581 C/T cg09795085 chr6:101329169 ASCC3 -0.42 -5.94 -0.31 7.04e-9 Neuroticism; LIHC cis rs9425766 0.640 rs9425756 chr1:173816586 C/T cg06124660 chr1:173389066 NA -0.34 -6.61 -0.34 1.44e-10 Life satisfaction; LIHC cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg18876405 chr7:65276391 NA 0.55 9.42 0.45 7.17e-19 Calcium levels; LIHC cis rs7584330 0.666 rs72620819 chr2:238354982 C/T cg14458575 chr2:238380390 NA 0.54 7.61 0.38 2.67e-13 Prostate cancer; LIHC cis rs4919087 0.683 rs11189121 chr10:99072036 T/C cg25902810 chr10:99078978 FRAT1 -0.6 -7.23 -0.36 3.16e-12 Monocyte count; LIHC cis rs16870629 1.000 rs16870629 chr5:1015063 C/T cg00278107 chr5:1061253 SLC12A7 -0.64 -9.96 -0.47 1.1e-20 QT interval; LIHC cis rs2257205 0.667 rs8081074 chr17:56836596 G/A cg12560992 chr17:57184187 TRIM37 0.68 7.44 0.37 8.24e-13 Pancreatic cancer; LIHC trans rs11098499 0.874 rs6832670 chr4:120118792 A/G cg25214090 chr10:38739885 LOC399744 0.45 7.27 0.37 2.49e-12 Corneal astigmatism; LIHC cis rs3809863 0.602 rs11650072 chr17:45393665 A/G cg25173405 chr17:45401733 C17orf57 -0.57 -8.27 -0.41 3.09e-15 Glaucoma (primary open-angle); LIHC cis rs12762955 0.561 rs7076107 chr10:1043647 T/C cg26597838 chr10:835615 NA -0.47 -5.88 -0.3 9.54e-9 Response to angiotensin II receptor blocker therapy; LIHC cis rs4638749 0.677 rs10185270 chr2:108838692 A/C cg25838818 chr2:108905173 SULT1C2 -0.4 -7.03 -0.36 1.15e-11 Blood pressure; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25423225 chr7:935108 C7orf20 0.42 6.36 0.33 6.38e-10 Bilirubin levels; LIHC cis rs1577917 0.771 rs9362232 chr6:86353622 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.36 -6.47 -0.33 3.45e-10 Response to antipsychotic treatment; LIHC cis rs2228479 0.850 rs11644213 chr16:89837367 C/T cg04013166 chr16:89971882 TCF25 -0.48 -5.76 -0.3 1.91e-8 Skin colour saturation; LIHC cis rs57244997 0.652 rs78477696 chr6:162428316 C/T cg17173639 chr6:162384350 PARK2 -0.54 -6.76 -0.34 6.14e-11 Mosquito bite size; LIHC cis rs7095944 0.584 rs4962692 chr10:126424823 G/A cg20435097 chr10:126320824 FAM53B 0.38 6.4 0.33 5.03e-10 Asthma; LIHC trans rs970548 0.697 rs11239540 chr10:45999209 T/C cg14222797 chr10:16859974 RSU1 -0.53 -6.2 -0.32 1.63e-9 Total cholesterol levels;Cholesterol, total;HDL cholesterol;HDL cholesterol levels; LIHC cis rs3820068 0.581 rs16851848 chr1:15927698 G/A cg17385448 chr1:15911702 AGMAT 0.34 5.85 0.3 1.12e-8 Systolic blood pressure; LIHC trans rs9929218 1.000 rs13333528 chr16:68790502 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.65 -9.58 -0.46 2.05e-19 Colorectal cancer; LIHC trans rs1814175 0.645 rs12364337 chr11:49942580 A/T cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC trans rs2262909 0.962 rs56369285 chr19:22267185 T/C cg17074339 chr11:11642133 GALNTL4 0.41 6.1 0.31 2.81e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs4975616 0.836 rs13178866 chr5:1323212 C/T cg07493874 chr5:1342172 CLPTM1L -0.68 -10.89 -0.51 6.66e-24 Lung cancer; LIHC cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg00149659 chr3:10157352 C3orf10 0.6 6.57 0.33 1.91e-10 Alzheimer's disease; LIHC cis rs116095464 0.614 rs10067482 chr5:219328 T/G cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs9303401 0.614 rs62084387 chr17:57148027 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 8.72 0.43 1.23e-16 Cognitive test performance; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg11905131 chr22:24372483 LOC391322 -0.63 -8.93 -0.43 2.66e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02179239 chr10:23002514 PIP4K2A 0.42 6.21 0.32 1.55e-9 Pancreatic cancer; LIHC cis rs11711311 1.000 rs11719303 chr3:113494524 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.9 -0.35 2.47e-11 IgG glycosylation; LIHC cis rs3096299 0.967 rs2965935 chr16:89481274 C/T cg08822215 chr16:89438651 ANKRD11 0.44 6.87 0.35 3.05e-11 Multiple myeloma (IgH translocation); LIHC cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg20887711 chr4:1340912 KIAA1530 -0.49 -7.44 -0.37 8.05e-13 Obesity-related traits; LIHC cis rs11711311 1.000 rs9851731 chr3:113502651 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 -0.37 -6.97 -0.35 1.6e-11 IgG glycosylation; LIHC cis rs2153535 0.580 rs9328486 chr6:8528008 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.19e-16 Motion sickness; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg12963096 chr13:39612675 NHLRC3;C13orf23 -0.44 -6.31 -0.32 8.52e-10 Triglycerides; LIHC cis rs9649465 0.905 rs3757504 chr7:123391750 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.04 -0.4 1.5e-14 Migraine; LIHC cis rs1691799 0.899 rs1183272 chr12:66735421 T/C cg16791601 chr12:66731901 HELB -0.57 -13.94 -0.6 2.8e-35 White blood cell count (basophil); LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg05590025 chr7:65112418 INTS4L2 0.61 6.71 0.34 7.92e-11 Diabetic kidney disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21902160 chr7:29689075 LOC646762 0.43 6.1 0.31 2.86e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg14159672 chr1:205819179 PM20D1 0.69 9.7 0.46 8.46e-20 Menarche (age at onset); LIHC cis rs9467773 0.967 rs9467775 chr6:26513435 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.89 0.6 4.28e-35 Intelligence (multi-trait analysis); LIHC cis rs28647808 0.881 rs7040821 chr9:136263584 C/A cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg03806693 chr22:41940476 POLR3H -1.08 -11.42 -0.53 8.04e-26 Vitiligo; LIHC cis rs6951245 0.554 rs75075857 chr7:1140298 C/T cg04025307 chr7:1156635 C7orf50 0.64 6.34 0.32 7.13e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg16132339 chr22:24313637 DDTL;DDT 0.71 13.66 0.59 3.41e-34 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7131987 0.903 rs11050162 chr12:29420054 T/G cg05697976 chr12:29376483 FAR2 0.31 6.24 0.32 1.33e-9 QT interval; LIHC cis rs4788570 0.624 rs9929985 chr16:71838458 A/G cg06353428 chr16:71660113 MARVELD3 1.29 12.98 0.57 1.4e-31 Intelligence (multi-trait analysis); LIHC cis rs2191566 0.821 rs59756444 chr19:44513656 C/G cg18700516 chr19:44507157 ZNF230 -0.35 -5.76 -0.3 1.84e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg11952622 chr19:58962976 ZNF324B -0.49 -7.57 -0.38 3.47e-13 Uric acid clearance; LIHC cis rs7208859 0.673 rs60020217 chr17:29185054 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7927592 0.913 rs4988291 chr11:68381607 G/A cg01657329 chr11:68192670 LRP5 -0.48 -6.21 -0.32 1.57e-9 Total body bone mineral density; LIHC cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg03264133 chr6:25882463 NA -0.67 -8.47 -0.42 7.61e-16 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.726 rs34344887 chr3:47042161 A/G cg27129171 chr3:47204927 SETD2 0.66 11.89 0.54 1.59e-27 Colorectal cancer; LIHC cis rs9486719 1.000 rs2179126 chr6:96871350 A/G cg06623918 chr6:96969491 KIAA0776 0.74 7.29 0.37 2.22e-12 Migraine;Coronary artery disease; LIHC cis rs61990749 0.597 rs17106157 chr14:78146878 C/T cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.71 0.38 1.35e-13 Fibroblast growth factor basic levels; LIHC cis rs6708331 0.517 rs7599072 chr2:70360006 C/T cg01613454 chr2:70366299 NA 0.38 6.11 0.31 2.75e-9 Obesity-related traits; LIHC cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg00656387 chr3:40428638 ENTPD3 -0.44 -7.42 -0.37 9.64e-13 Renal cell carcinoma; LIHC cis rs7412746 0.611 rs10888398 chr1:150886782 A/G cg18016565 chr1:150552671 MCL1 -0.5 -9.54 -0.46 2.73e-19 Melanoma; LIHC cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.1 -17.18 -0.68 3.93e-48 Gut microbiome composition (summer); LIHC cis rs17685 0.712 rs6976236 chr7:75741087 G/T cg16684958 chr7:75615977 POR 0.51 8.59 0.42 3.18e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2455826 0.500 rs2455852 chr3:15688688 C/T cg12698662 chr3:15914712 MIR563 -0.34 -6.22 -0.32 1.49e-9 Inflammatory skin disease; LIHC cis rs7618501 0.633 rs11925192 chr3:50038664 G/A cg21467203 chr3:49911342 NA -0.43 -7.87 -0.39 4.85e-14 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.528 rs309167 chr2:136669264 C/T cg07305463 chr2:136567211 LCT -0.39 -5.98 -0.31 5.48e-9 Corneal structure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06387028 chr7:72395397 POM121 0.44 6.35 0.32 6.77e-10 Pancreatic cancer; LIHC cis rs7772486 0.875 rs863820 chr6:146347402 C/T cg05347473 chr6:146136440 FBXO30 -0.4 -6.46 -0.33 3.62e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11764590 0.671 rs12669370 chr7:2081914 G/A cg23043544 chr7:2124092 MAD1L1 -0.45 -7.33 -0.37 1.64e-12 Neuroticism; LIHC cis rs7727544 0.735 rs274566 chr5:131715011 A/G cg07395648 chr5:131743802 NA 0.32 6.69 0.34 9.24e-11 Blood metabolite levels; LIHC cis rs4819052 0.765 rs2838854 chr21:46680364 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.66 0.53 1.08e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7772486 0.597 rs1970306 chr6:146154543 A/G cg05347473 chr6:146136440 FBXO30 0.48 7.21 0.36 3.71e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs2576037 0.526 rs626217 chr18:44429182 T/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.55 -0.33 2.06e-10 Personality dimensions; LIHC cis rs9419702 0.568 rs7075233 chr10:133545170 A/G cg20568497 chr10:133558893 NA -0.4 -6.03 -0.31 4.31e-9 Survival in rectal cancer; LIHC cis rs2816062 0.775 rs2745315 chr1:18897118 G/A cg18795169 chr1:18902165 NA -0.8 -18.05 -0.7 1.24e-51 Urate levels in lean individuals; LIHC trans rs561341 1.000 rs501957 chr17:30314504 C/T cg20587970 chr11:113659929 NA -1.18 -10.63 -0.5 5.45e-23 Hip circumference adjusted for BMI; LIHC cis rs7296418 0.961 rs1790094 chr12:123586688 T/C cg06742321 chr12:123595122 PITPNM2 0.31 5.75 0.3 1.98e-8 Platelet count; LIHC cis rs9309711 0.666 rs11127430 chr2:3485242 G/C cg04359351 chr2:3481828 TTC15 0.29 6.04 0.31 3.92e-9 Neurofibrillary tangles; LIHC cis rs35306767 0.903 rs35968821 chr10:910225 A/G cg20503657 chr10:835505 NA 1.07 12.48 0.56 9.98e-30 Eosinophil percentage of granulocytes; LIHC cis rs7617773 0.743 rs13071960 chr3:48367537 A/G cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.29 -0.45 1.83e-18 Bipolar disorder; LIHC cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.48 0.56 1.07e-29 Alzheimer's disease; LIHC cis rs11690935 0.959 rs6724337 chr2:172735329 C/T cg13550731 chr2:172543902 DYNC1I2 -0.9 -16.97 -0.68 2.62e-47 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg20686432 chr4:184365613 CDKN2AIP 0.52 6.73 0.34 7.26e-11 Hepatitis; LIHC cis rs9733 0.596 rs11582840 chr1:150688487 A/G cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs9814567 1.000 rs7432268 chr3:134242051 T/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7833790 0.724 rs6473310 chr8:82707981 A/G cg17211192 chr8:82754475 SNX16 -0.63 -11.89 -0.54 1.59e-27 Diastolic blood pressure; LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.72 12.45 0.56 1.35e-29 Prudent dietary pattern; LIHC cis rs28374715 0.532 rs11070328 chr15:41651569 T/C cg18705301 chr15:41695430 NDUFAF1 -1.22 -18.35 -0.7 7.66e-53 Ulcerative colitis; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg16396417 chr19:59085259 MZF1;LOC100131691 -0.54 -6.15 -0.32 2.16e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs9902453 0.899 rs8067580 chr17:28471248 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.41 0.45 7.5e-19 Coffee consumption (cups per day); LIHC cis rs7613875 0.543 rs34034116 chr3:49959156 C/A cg24110177 chr3:50126178 RBM5 -0.55 -8.78 -0.43 7.71e-17 Body mass index; LIHC trans rs2727020 0.521 rs7107178 chr11:49526668 G/A cg18944383 chr4:111397179 ENPEP -0.35 -8.1 -0.4 9.97e-15 Coronary artery disease; LIHC cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg13047869 chr3:10149882 C3orf24 0.51 6.18 0.32 1.82e-9 Alzheimer's disease; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs4795359 chr17:37573146 C/T cg00129232 chr17:37814104 STARD3 -0.4 -6.43 -0.33 4.4e-10 Glomerular filtration rate (creatinine); LIHC cis rs96067 0.805 rs3767705 chr1:36602044 A/T cg24686825 chr1:36642396 MAP7D1 -0.36 -6.03 -0.31 4.36e-9 Corneal structure; LIHC trans rs1728785 1.000 rs1728781 chr16:68567794 A/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.49 6.18 0.32 1.88e-9 Ulcerative colitis; LIHC cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg13770153 chr20:60521292 NA -0.59 -12.73 -0.57 1.18e-30 Obesity-related traits; LIHC cis rs10751667 0.643 rs7395592 chr11:934094 C/G cg06064525 chr11:970664 AP2A2 -0.55 -14.76 -0.62 1.69e-38 Alzheimer's disease (late onset); LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC cis rs2816062 0.775 rs2816048 chr1:18893763 T/C cg18795169 chr1:18902165 NA -0.8 -17.87 -0.69 6.82e-51 Urate levels in lean individuals; LIHC cis rs736408 0.812 rs2270197 chr3:52824095 T/G cg11645453 chr3:52864694 ITIH4 0.23 6.0 0.31 4.94e-9 Bipolar disorder; LIHC cis rs35110281 0.743 rs2329443 chr21:45059431 C/T cg21573476 chr21:45109991 RRP1B -0.57 -10.76 -0.5 1.85e-23 Mean corpuscular volume; LIHC cis rs7659604 0.540 rs13140070 chr4:122713899 C/T cg19671926 chr4:122722719 EXOSC9 0.56 8.61 0.42 2.64e-16 Type 2 diabetes; LIHC cis rs763121 0.853 rs3747172 chr22:39067524 A/G cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs965469 1.000 rs2236107 chr20:3285821 C/T cg25506879 chr20:3388711 C20orf194 -0.57 -6.54 -0.33 2.27e-10 IFN-related cytopenia; LIHC cis rs735860 0.726 rs209519 chr6:53208680 G/A cg10236188 chr6:53219634 NA 0.42 7.83 0.39 6.26e-14 Glaucoma; LIHC cis rs9911578 0.785 rs10853008 chr17:56993407 T/C cg12560992 chr17:57184187 TRIM37 -0.86 -13.49 -0.59 1.55e-33 Intelligence (multi-trait analysis); LIHC cis rs763121 0.853 rs2267395 chr22:39113903 C/T cg14440974 chr22:39074834 NA -0.36 -6.07 -0.31 3.36e-9 Menopause (age at onset); LIHC cis rs75908454 1.000 rs75712439 chr6:169982682 T/A cg19338460 chr6:170058176 WDR27 -0.79 -7.58 -0.38 3.35e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs7107174 1.000 rs10501426 chr11:78057122 C/T cg02023728 chr11:77925099 USP35 0.43 8.33 0.41 2.02e-15 Testicular germ cell tumor; LIHC cis rs9916302 0.861 rs7503514 chr17:37669884 G/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.3 -0.58 8.13e-33 Glomerular filtration rate (creatinine); LIHC cis rs5753037 0.543 rs140122 chr22:30138908 C/G cg01021169 chr22:30184971 ASCC2 -0.32 -5.97 -0.31 5.83e-9 Type 1 diabetes; LIHC cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg12034118 chr1:209979487 IRF6 0.38 5.8 0.3 1.52e-8 Cleft lip with or without cleft palate; LIHC cis rs11105298 0.891 rs10777184 chr12:89919568 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.28 -0.37 2.34e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs4650994 0.525 rs2493860 chr1:178541492 A/G cg05059571 chr16:84539110 KIAA1609 -0.45 -7.41 -0.37 9.97e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs6456156 0.603 rs2345754 chr6:167484361 T/C cg12798992 chr6:167411361 FGFR1OP 0.44 6.65 0.34 1.13e-10 Primary biliary cholangitis; LIHC cis rs72634258 0.554 rs12092614 chr1:7865710 C/T cg26816564 chr1:7831052 VAMP3 0.64 6.17 0.32 1.95e-9 Inflammatory bowel disease; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.96e-16 Prudent dietary pattern; LIHC cis rs35110281 0.840 rs7276633 chr21:45078800 C/T cg21573476 chr21:45109991 RRP1B -0.5 -9.36 -0.45 1.13e-18 Mean corpuscular volume; LIHC cis rs1559088 0.847 rs7254758 chr19:33608047 T/A cg27124370 chr19:33622961 WDR88 0.52 8.39 0.41 1.32e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg06636001 chr8:8085503 FLJ10661 -0.56 -9.44 -0.45 6.15e-19 Mood instability; LIHC cis rs9858542 0.953 rs9853683 chr3:49512588 A/G cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs644799 1.000 rs500054 chr11:95593806 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.75 0.3 1.95e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9790314 0.521 rs60625846 chr3:161084525 G/T cg03342759 chr3:160939853 NMD3 -0.43 -6.25 -0.32 1.23e-9 Morning vs. evening chronotype; LIHC cis rs644799 0.648 rs1255182 chr11:95472391 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.62 10.36 0.49 4.63e-22 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12908161 0.959 rs2175567 chr15:85200946 C/G cg17507749 chr15:85114479 UBE2QP1 0.68 7.71 0.38 1.36e-13 Schizophrenia; LIHC cis rs904251 0.828 rs1757178 chr6:37486310 C/T cg25019722 chr6:37503610 NA 0.38 6.37 0.33 5.95e-10 Cognitive performance; LIHC cis rs7534824 0.507 rs61780294 chr1:101398011 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.91 0.39 3.5e-14 Refractive astigmatism; LIHC cis rs7904368 0.707 rs12253979 chr10:16853415 T/C cg23933602 chr10:16859644 RSU1 0.59 5.82 0.3 1.32e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs6960043 0.714 rs4719430 chr7:15047280 C/G cg19272540 chr7:15055459 NA -0.25 -6.92 -0.35 2.21e-11 Type 2 diabetes; LIHC trans rs2243480 0.901 rs778693 chr7:65872345 T/G cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg06634786 chr22:41940651 POLR3H -0.78 -8.55 -0.42 4.1e-16 Vitiligo; LIHC cis rs597539 0.652 rs501799 chr11:68631240 G/T cg04772025 chr11:68637568 NA 0.47 6.41 0.33 4.95e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1801251 0.896 rs2305141 chr2:233684402 A/G cg25237894 chr2:233734115 C2orf82 -0.54 -9.96 -0.47 1.07e-20 Coronary artery disease; LIHC trans rs1814175 0.817 rs7483795 chr11:49704930 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.27 -0.78 1.83e-72 Height; LIHC cis rs17125944 0.505 rs28568967 chr14:53223060 A/G cg13660082 chr14:53194042 PSMC6 -0.44 -7.65 -0.38 2e-13 Alzheimer's disease (late onset); LIHC cis rs11122272 0.735 rs2256908 chr1:231506557 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs748404 0.697 rs493177 chr15:43543258 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.39 6.14 0.32 2.24e-9 Lung cancer; LIHC cis rs4727027 0.704 rs12704083 chr7:148909759 G/A cg23583168 chr7:148888333 NA -0.69 -10.81 -0.5 1.24e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs12497850 0.931 rs7628719 chr3:48995487 C/T cg07636037 chr3:49044803 WDR6 0.9 16.03 0.65 1.61e-43 Parkinson's disease; LIHC cis rs9303401 0.614 rs35245220 chr17:56510305 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.9 11.62 0.53 1.6e-26 Cognitive test performance; LIHC cis rs748404 0.631 rs6493084 chr15:43647627 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.99 0.48 9e-21 Lung cancer; LIHC cis rs12048904 0.619 rs10875346 chr1:101328083 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 10.28 0.49 8.81e-22 Multiple sclerosis; LIHC cis rs6570726 0.791 rs9390336 chr6:145896823 A/T cg23711669 chr6:146136114 FBXO30 0.71 12.52 0.56 7e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg06212747 chr3:49208901 KLHDC8B 0.63 8.61 0.42 2.74e-16 Menarche (age at onset); LIHC cis rs9902453 0.904 rs9900112 chr17:28282910 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.63 0.59 4.53e-34 Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12187049 chr5:70882888 MCCC2 0.48 6.63 0.34 1.28e-10 Pancreatic cancer; LIHC cis rs372883 0.638 rs371432 chr21:30710876 G/A cg24692254 chr21:30365293 RNF160 -0.5 -6.25 -0.32 1.19e-9 Pancreatic cancer; LIHC cis rs2073499 1.000 rs2071803 chr3:50407344 G/T cg09545109 chr3:50388910 TUSC4;CYB561D2 0.71 7.84 0.39 5.67e-14 Schizophrenia; LIHC cis rs785830 0.689 rs1536608 chr9:223613 T/G cg14500300 chr9:211689 NA 0.3 6.74 0.34 6.76e-11 Platelet distribution width; LIHC cis rs11098499 0.615 rs59867181 chr4:120556467 C/T cg09307838 chr4:120376055 NA -0.56 -8.67 -0.42 1.81e-16 Corneal astigmatism; LIHC cis rs992157 0.735 rs12990082 chr2:219102332 C/T cg00012203 chr2:219082015 ARPC2 0.92 16.75 0.67 2.14e-46 Colorectal cancer; LIHC cis rs7336332 0.511 rs7998978 chr13:27999457 T/C cg22138327 chr13:27999177 GTF3A 0.64 10.13 0.48 2.84e-21 Weight; LIHC cis rs60871478 1.000 rs34260834 chr7:822958 A/G cg04727924 chr7:799746 HEATR2 -0.57 -8.6 -0.42 2.97e-16 Cerebrospinal P-tau181p levels; LIHC cis rs9399135 0.935 rs987690 chr6:135350379 A/G cg24558204 chr6:135376177 HBS1L 0.43 7.0 0.35 1.37e-11 Red blood cell count; LIHC cis rs35883536 0.647 rs10875316 chr1:101044150 G/A cg14515779 chr1:101123966 NA 0.48 6.95 0.35 1.83e-11 Monocyte count; LIHC trans rs7618501 0.521 rs3796386 chr3:49899795 G/A cg21659725 chr3:3221576 CRBN 0.57 8.26 0.41 3.18e-15 Intelligence (multi-trait analysis); LIHC cis rs2075371 0.965 rs2544216 chr7:133987902 G/A cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC trans rs875971 0.660 rs79009421 chr7:66068509 G/C cg26939375 chr7:64535504 NA -0.43 -6.97 -0.35 1.65e-11 Aortic root size; LIHC cis rs600806 0.665 rs1368988 chr1:110012123 A/T cg11161837 chr1:110010384 SYPL2 0.46 6.46 0.33 3.6e-10 Intelligence (multi-trait analysis); LIHC cis rs7223966 1.000 rs7214312 chr17:61870863 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.76 0.34 5.99e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs8005677 1.000 rs10148215 chr14:23382345 C/T cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs769267 0.895 rs2916069 chr19:19520358 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.42 5.89 0.3 9.18e-9 Tonsillectomy; LIHC cis rs17152411 1.000 rs1807099 chr10:126593774 C/T cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs644799 0.965 rs598876 chr11:95560853 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg07649862 chr16:88897202 GALNS 0.44 6.56 0.33 2.03e-10 Immature fraction of reticulocytes; LIHC cis rs2108622 0.727 rs62106157 chr19:15980448 G/A cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.74 0.34 6.9e-11 Gut microbiome composition (summer); LIHC cis rs8177179 0.967 rs9820225 chr3:133449189 A/G cg16262614 chr3:133464971 TF 0.46 10.36 0.49 4.53e-22 Iron status biomarkers (transferrin levels); LIHC cis rs801193 0.967 rs2420827 chr7:66147101 G/A cg11764359 chr7:65958608 NA -0.68 -10.01 -0.48 7.6e-21 Aortic root size; LIHC cis rs8180040 0.587 rs1466741 chr3:47247214 C/T cg16586182 chr3:47516702 SCAP 0.48 8.63 0.42 2.29e-16 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08535411 chr7:151826219 NA 0.41 6.49 0.33 3.06e-10 Cognitive function; LIHC trans rs2727020 0.521 rs10839299 chr11:49573981 C/T cg18944383 chr4:111397179 ENPEP 0.35 8.19 0.4 5.35e-15 Coronary artery disease; LIHC cis rs6542838 0.702 rs6419564 chr2:99534113 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -6.69 -0.34 9.06e-11 Fear of minor pain; LIHC cis rs611744 0.647 rs676654 chr8:109242303 A/G cg21045802 chr8:109455806 TTC35 0.55 9.14 0.44 5.75e-18 Dupuytren's disease; LIHC cis rs9399135 0.527 rs61738492 chr6:135282771 G/A cg24558204 chr6:135376177 HBS1L 0.61 10.26 0.48 1.08e-21 Red blood cell count; LIHC cis rs12477438 0.834 rs1563106 chr2:99701381 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -9.08 -0.44 8.53e-18 Chronic sinus infection; LIHC cis rs2404602 0.692 rs35395069 chr15:76986334 C/T cg03037974 chr15:76606532 NA 0.74 14.58 0.62 8.72e-38 Blood metabolite levels; LIHC cis rs10751667 0.961 rs7396670 chr11:929269 A/G cg06064525 chr11:970664 AP2A2 -0.48 -12.05 -0.55 3.99e-28 Alzheimer's disease (late onset); LIHC cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg11644478 chr21:40555479 PSMG1 -0.39 -6.21 -0.32 1.55e-9 Menarche (age at onset); LIHC trans rs916888 0.821 rs199507 chr17:44858855 A/G cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg21724239 chr8:58056113 NA 0.62 7.88 0.39 4.48e-14 Developmental language disorder (linguistic errors); LIHC cis rs6061231 0.958 rs2379126 chr20:60953005 C/A cg24112000 chr20:60950667 NA -0.6 -8.34 -0.41 1.78e-15 Colorectal cancer; LIHC cis rs17253792 0.749 rs45458197 chr14:56145018 A/T cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC trans rs4566357 0.615 rs2272202 chr2:227914625 C/T cg16088116 chr21:44841560 SIK1 0.41 6.46 0.33 3.58e-10 Coronary artery disease; LIHC cis rs12477438 0.520 rs36071868 chr2:99737120 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC cis rs943466 0.513 rs755497 chr6:33734419 C/T cg25922239 chr6:33757077 LEMD2 -0.43 -7.0 -0.35 1.35e-11 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs172166 0.694 rs203876 chr6:28046673 T/C cg23485639 chr6:28045615 ZNF165 0.39 6.02 0.31 4.39e-9 Cardiac Troponin-T levels; LIHC cis rs7927592 0.763 rs624003 chr11:68231240 C/T cg01657329 chr11:68192670 LRP5 -0.49 -7.2 -0.36 3.74e-12 Total body bone mineral density; LIHC cis rs17152411 1.000 rs61873263 chr10:126589202 G/A cg07906193 chr10:126599966 NA 0.42 6.61 0.34 1.48e-10 Height; LIHC cis rs16854884 0.586 rs7650172 chr3:143729408 G/C cg06585982 chr3:143692056 C3orf58 0.56 7.28 0.37 2.32e-12 Economic and political preferences (feminism/equality); LIHC trans rs800082 0.501 rs9844730 chr3:144216886 T/G cg24215973 chr2:240111563 HDAC4 0.45 6.43 0.33 4.25e-10 Smoking behavior; LIHC cis rs10751667 0.643 rs7396623 chr11:934104 G/A ch.11.42038R chr11:967971 AP2A2 0.54 9.88 0.47 2.02e-20 Alzheimer's disease (late onset); LIHC cis rs11764590 0.651 rs12673687 chr7:2081873 C/T cg23043544 chr7:2124092 MAD1L1 -0.45 -7.31 -0.37 1.87e-12 Neuroticism; LIHC trans rs7668874 0.731 rs9990651 chr4:116814979 A/G cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs6964587 1.000 rs17164275 chr7:91590408 A/G cg17063962 chr7:91808500 NA 1.02 19.53 0.73 1.36e-57 Breast cancer; LIHC cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg16822855 chr3:40428330 ENTPD3 0.35 6.38 0.33 5.91e-10 Renal cell carcinoma; LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg07424592 chr7:64974309 NA -0.44 -6.69 -0.34 8.93e-11 Calcium levels; LIHC cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg10802521 chr3:52805072 NEK4 -0.45 -7.66 -0.38 1.88e-13 Electroencephalogram traits; LIHC cis rs7614311 0.681 rs73117036 chr3:63892725 G/C cg22134162 chr3:63841271 THOC7 -0.53 -6.03 -0.31 4.21e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs611744 0.608 rs1448152 chr8:109278249 C/T cg21045802 chr8:109455806 TTC35 0.59 10.33 0.49 5.93e-22 Dupuytren's disease; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25043602 chr13:113489734 ATP11A 0.43 6.21 0.32 1.55e-9 Bilirubin levels; LIHC trans rs1814175 0.817 rs11518158 chr11:49985633 G/T cg18944383 chr4:111397179 ENPEP 0.27 7.06 0.36 9.47e-12 Height; LIHC cis rs722599 0.748 rs2537824 chr14:75367349 T/C cg11812906 chr14:75593930 NEK9 -0.43 -6.99 -0.35 1.47e-11 IgG glycosylation; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.84 0.63 8.46e-39 Prudent dietary pattern; LIHC cis rs2153535 0.601 rs9505472 chr6:8538765 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.51 0.42 5.35e-16 Motion sickness; LIHC cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg12373951 chr3:133503437 NA 0.47 7.88 0.39 4.54e-14 Iron status biomarkers; LIHC cis rs10744422 0.528 rs6489245 chr12:123360151 G/A cg25930673 chr12:123319894 HIP1R -0.85 -9.91 -0.47 1.57e-20 Schizophrenia; LIHC cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg15691649 chr6:25882328 NA 0.5 7.07 0.36 8.51e-12 Blood metabolite levels; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 20.86 0.75 6.63e-63 Prudent dietary pattern; LIHC cis rs763121 0.853 rs4821809 chr22:39065743 G/C cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs616402 0.527 rs589151 chr1:10567711 C/T cg17425144 chr1:10567563 PEX14 0.63 13.25 0.58 1.25e-32 Breast size; LIHC cis rs11583043 0.831 rs6667818 chr1:101412313 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 8.49 0.42 6.56e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1862618 0.671 rs2255726 chr5:56243128 T/C cg12311346 chr5:56204834 C5orf35 0.46 6.18 0.32 1.84e-9 Initial pursuit acceleration; LIHC cis rs2153535 0.580 rs9328478 chr6:8519183 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.68 0.42 1.64e-16 Motion sickness; LIHC cis rs1215050 0.755 rs2952911 chr4:98850666 T/C cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.61e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg13047869 chr3:10149882 C3orf24 0.5 6.5 0.33 2.83e-10 Alzheimer's disease; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg06873352 chr17:61820015 STRADA -0.71 -12.63 -0.56 2.9e-30 Prudent dietary pattern; LIHC cis rs7772486 0.743 rs9376955 chr6:145949404 T/A cg23711669 chr6:146136114 FBXO30 0.59 10.77 0.5 1.69e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7512552 0.780 rs1260411 chr1:150382088 G/A cg15654264 chr1:150340011 RPRD2 0.68 11.1 0.51 1.2e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs68170813 0.559 rs10953531 chr7:106827867 A/G cg02696742 chr7:106810147 HBP1 0.5 5.73 0.3 2.23e-8 Coronary artery disease; LIHC cis rs9640161 0.659 rs7788316 chr7:150013995 A/T cg10018233 chr7:150070692 REPIN1 0.5 8.42 0.41 1.08e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs875971 0.660 rs13224319 chr7:66007363 A/G cg14393609 chr7:65229607 NA 0.37 5.84 0.3 1.22e-8 Aortic root size; LIHC cis rs10276381 0.579 rs73072543 chr7:28146850 A/G cg23620719 chr7:28220237 JAZF1 0.63 7.04 0.36 1.05e-11 Crohn's disease; LIHC cis rs1912483 0.545 rs35161461 chr17:45401757 A/G cg08085267 chr17:45401833 C17orf57 -0.61 -8.17 -0.4 6.16e-15 Coronary artery disease; LIHC cis rs858239 0.600 rs2072369 chr7:23146189 A/G cg23682824 chr7:23144976 KLHL7 0.47 7.09 0.36 7.74e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs2242116 0.727 rs10865943 chr3:46969970 T/C cg02527881 chr3:46936655 PTH1R -0.5 -10.86 -0.51 8.1e-24 Birth weight; LIHC cis rs2120019 0.938 rs8036573 chr15:75308690 C/T cg09165964 chr15:75287851 SCAMP5 -0.61 -9.46 -0.46 5.24e-19 Blood trace element (Zn levels); LIHC trans rs6461049 0.800 rs3800913 chr7:2163237 A/G cg04565464 chr8:145669602 NFKBIL2 0.38 6.33 0.32 7.57e-10 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06589161 chr5:180618230 NA 0.41 6.35 0.32 7e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4073582 0.555 rs521109 chr11:66030948 G/A cg16950941 chr11:66035639 RAB1B 0.6 9.12 0.44 6.67e-18 Gout; LIHC cis rs1059312 0.932 rs4760593 chr12:129287220 A/G cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -14.35 -0.61 6.85e-37 Systemic lupus erythematosus; LIHC cis rs3741404 0.620 rs882147 chr11:63976689 T/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 12.51 0.56 7.93e-30 Platelet count; LIHC trans rs944289 0.746 rs7145546 chr14:36558246 G/C cg15660807 chr2:220381734 ACCN4 -0.26 -6.3 -0.32 8.94e-10 Thyroid cancer; LIHC cis rs1577917 1.000 rs12199516 chr6:86726221 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.12 -0.48 3.03e-21 Response to antipsychotic treatment; LIHC cis rs12477438 0.798 rs1453562 chr2:99615850 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.55 -0.53 2.75e-26 Chronic sinus infection; LIHC cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg11764359 chr7:65958608 NA -0.56 -5.86 -0.3 1.09e-8 Diabetic kidney disease; LIHC cis rs17376456 0.809 rs10476602 chr5:93445255 T/C cg25358565 chr5:93447407 FAM172A 1.15 10.7 0.5 3.08e-23 Diabetic retinopathy; LIHC cis rs2708977 0.901 rs2579505 chr2:97167962 T/C cg01950434 chr2:97203154 ARID5A -0.51 -7.51 -0.38 5.14e-13 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs1005277 0.579 rs2474571 chr10:38384639 T/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs10256972 0.900 rs7812072 chr7:1053862 A/G cg07308232 chr7:1071921 C7orf50 -0.5 -8.31 -0.41 2.3e-15 Longevity;Endometriosis; LIHC cis rs11711311 0.955 rs12630833 chr3:113390883 G/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.36 6.18 0.32 1.8e-9 IgG glycosylation; LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg11766577 chr21:47581405 C21orf56 0.43 7.15 0.36 5.39e-12 Testicular germ cell tumor; LIHC cis rs9902453 0.716 rs3098949 chr17:27978694 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.89 0.57 2.91e-31 Coffee consumption (cups per day); LIHC cis rs7208859 0.673 rs9907197 chr17:29018263 C/T cg13385521 chr17:29058706 SUZ12P 0.69 7.3 0.37 2.04e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11673344 0.764 rs529468 chr19:37446200 T/G cg27390819 chr19:37464633 NA -0.53 -6.38 -0.33 5.79e-10 Obesity-related traits; LIHC cis rs4253772 0.637 rs9627350 chr22:46663017 A/G cg09491104 chr22:46646882 C22orf40 -0.69 -8.11 -0.4 9.08e-15 LDL cholesterol;Cholesterol, total; LIHC cis rs1570884 0.516 rs7334387 chr13:50172133 T/A cg08779649 chr13:50194554 NA 0.35 6.41 0.33 4.8e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs1215050 0.755 rs811479 chr4:98727398 A/T cg05340658 chr4:99064831 C4orf37 0.39 5.8 0.3 1.51e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs861020 0.527 rs614662 chr1:209962419 C/T cg21951975 chr1:209979733 IRF6 -0.37 -5.96 -0.31 6.4e-9 Orofacial clefts; LIHC cis rs11122272 0.735 rs2790880 chr1:231534259 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.63 0.46 1.45e-19 Hemoglobin concentration; LIHC cis rs9303401 0.615 rs35288118 chr17:56600748 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.99 13.46 0.59 2.04e-33 Cognitive test performance; LIHC cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.29 -5.94 -0.31 7.15e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs875971 0.929 rs34406470 chr7:65929956 A/G cg11764359 chr7:65958608 NA 0.89 15.98 0.65 2.56e-43 Aortic root size; LIHC cis rs847649 0.842 rs11976237 chr7:102641383 A/G cg18108683 chr7:102477205 FBXL13 0.44 6.6 0.34 1.57e-10 Morning vs. evening chronotype; LIHC cis rs11112613 0.762 rs73184077 chr12:105949999 G/A cg03607813 chr12:105948248 NA 0.67 13.37 0.59 4.49e-33 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs12701220 0.503 rs13222294 chr7:1172969 G/A cg02733842 chr7:1102375 C7orf50 -0.69 -7.24 -0.36 3.05e-12 Bronchopulmonary dysplasia; LIHC cis rs10979 1.000 rs12203151 chr6:143884856 C/T cg25407410 chr6:143891975 LOC285740 -0.39 -6.21 -0.32 1.55e-9 Hypospadias; LIHC cis rs9303280 0.776 rs9891174 chr17:38031802 T/A cg11212589 chr17:38028394 ZPBP2 0.36 7.25 0.37 2.75e-12 Self-reported allergy; LIHC cis rs910316 1.000 rs175436 chr14:75608683 C/G cg11812906 chr14:75593930 NEK9 -0.73 -14.38 -0.61 5.39e-37 Height; LIHC cis rs9649213 0.613 rs6961129 chr7:97975542 T/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.94 -0.31 7.14e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs34330 0.562 rs11055023 chr12:12853197 A/G cg09462578 chr12:12878428 APOLD1 -0.77 -10.24 -0.48 1.22e-21 Systemic lupus erythematosus; LIHC cis rs4975709 0.609 rs2232373 chr5:1882280 C/G cg15595755 chr5:1867978 NA 0.34 6.13 0.31 2.4e-9 Cardiovascular disease risk factors; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11011602 chr9:136215029 SNORD24;MED22;RPL7A -0.52 -6.67 -0.34 1.04e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.98 -0.4 2.17e-14 Lymphocyte counts; LIHC cis rs6754311 0.593 rs1438305 chr2:136502792 C/G cg15123519 chr2:136567270 LCT 0.44 8.69 0.43 1.52e-16 Mosquito bite size; LIHC cis rs9628987 0.569 rs11121176 chr1:8437032 T/C cg20416874 chr1:8611966 RERE 0.49 5.84 0.3 1.19e-8 Breast cancer; LIHC cis rs78062588 1.000 rs73001420 chr1:154586759 C/G cg24304309 chr1:154577895 ADAR -0.5 -5.86 -0.3 1.11e-8 Lung cancer; LIHC cis rs10876993 0.928 rs1689596 chr12:58053029 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.59 -0.34 1.65e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs7903847 0.600 rs2275582 chr10:99128983 G/A cg06359132 chr10:99160096 RRP12 -0.4 -5.82 -0.3 1.35e-8 Granulocyte percentage of myeloid white cells; LIHC trans rs61931739 0.534 rs11052984 chr12:34045904 T/C cg26384229 chr12:38710491 ALG10B 0.47 6.62 0.34 1.36e-10 Morning vs. evening chronotype; LIHC cis rs34172651 0.917 rs7204281 chr16:24784475 C/T cg00152838 chr16:24741724 TNRC6A -0.45 -6.1 -0.31 2.87e-9 Intelligence (multi-trait analysis); LIHC cis rs12478296 1.000 rs11899408 chr2:243014630 A/G cg05760424 chr2:242988095 NA -0.48 -6.76 -0.34 5.96e-11 Obesity-related traits; LIHC cis rs7584330 0.744 rs10929235 chr2:238380272 A/G cg14458575 chr2:238380390 NA 0.54 8.05 0.4 1.38e-14 Prostate cancer; LIHC cis rs459571 0.883 rs2520096 chr9:136919416 A/G cg13789015 chr9:136890014 NCRNA00094 0.46 8.42 0.41 1.07e-15 Platelet distribution width; LIHC cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg23172400 chr8:95962367 TP53INP1 -0.36 -8.03 -0.4 1.55e-14 Type 2 diabetes; LIHC cis rs950776 0.518 rs62008194 chr15:78813805 G/T cg06917634 chr15:78832804 PSMA4 0.93 14.06 0.61 9.61e-36 Sudden cardiac arrest; LIHC cis rs10744422 1.000 rs4759387 chr12:123377569 C/T cg25930673 chr12:123319894 HIP1R -0.86 -10.63 -0.5 5.33e-23 Schizophrenia; LIHC cis rs8002861 0.935 rs7318147 chr13:44445153 C/G cg17862404 chr13:45009330 TSC22D1 0.41 5.74 0.3 2.05e-8 Leprosy; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg26634121 chr16:88897219 GALNS 0.43 6.54 0.33 2.29e-10 Electroencephalogram traits; LIHC cis rs936229 0.654 rs762551 chr15:75041917 C/A cg14664628 chr15:75095509 CSK -0.84 -14.05 -0.61 9.87e-36 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs3099143 1.000 rs4243043 chr15:77178540 A/G cg21673338 chr15:77095150 SCAPER 0.48 7.63 0.38 2.3e-13 Recalcitrant atopic dermatitis; LIHC trans rs2727020 0.573 rs7925419 chr11:49231859 C/T cg03929089 chr4:120376271 NA -0.51 -8.21 -0.41 4.73e-15 Coronary artery disease; LIHC cis rs4148883 0.675 rs10000357 chr4:100099942 G/C cg12011299 chr4:100065546 ADH4 0.36 7.16 0.36 4.98e-12 Alcohol dependence; LIHC cis rs10256972 0.626 rs62433138 chr7:1050877 T/C cg16145915 chr7:1198662 ZFAND2A -0.26 -6.09 -0.31 3.01e-9 Longevity;Endometriosis; LIHC cis rs6952808 0.595 rs2398705 chr7:2164995 G/A cg04267008 chr7:1944627 MAD1L1 -0.53 -8.22 -0.41 4.26e-15 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.21 0.55 1.08e-28 Prudent dietary pattern; LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg06420487 chr17:61919686 SMARCD2 0.43 5.91 0.3 8.42e-9 Height; LIHC cis rs412000 0.554 rs2680700 chr17:56440542 G/T cg25039879 chr17:56429692 SUPT4H1 0.6 7.83 0.39 6.21e-14 Primary tooth development (time to first tooth eruption); LIHC cis rs2204008 0.640 rs2320744 chr12:38162389 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs1048238 0.506 rs698889 chr1:16267040 A/C cg00529422 chr1:16285251 ZBTB17 0.33 6.13 0.31 2.42e-9 Systolic blood pressure; LIHC cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg12463550 chr7:65579703 CRCP 0.71 7.44 0.37 8.23e-13 Diabetic kidney disease; LIHC cis rs7312933 0.510 rs1907705 chr12:42451122 T/A cg01256987 chr12:42539512 GXYLT1 -0.64 -11.79 -0.54 3.71e-27 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9858542 0.903 rs35999162 chr3:49597230 C/G cg03060546 chr3:49711283 APEH -0.47 -6.35 -0.32 6.85e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27001534 chr5:443220 C5orf55;EXOC3 0.55 7.09 0.36 7.61e-12 Lung function (FEV1/FVC); LIHC cis rs9467773 1.000 rs9461259 chr6:26504835 C/A cg09904177 chr6:26538194 HMGN4 0.66 13.85 0.6 6.03e-35 Intelligence (multi-trait analysis); LIHC cis rs2576037 0.526 rs2257027 chr18:44566990 A/T cg19077165 chr18:44547161 KATNAL2 0.45 6.94 0.35 1.92e-11 Personality dimensions; LIHC cis rs2075371 1.000 rs2241334 chr7:133979225 C/G cg20476274 chr7:133979776 SLC35B4 0.75 13.04 0.58 7.78e-32 Mean platelet volume; LIHC cis rs67460515 0.852 rs2404341 chr3:161092405 T/C cg17135325 chr3:160939158 NMD3 0.53 7.58 0.38 3.17e-13 Parkinson's disease; LIHC trans rs3960554 0.610 rs11971800 chr7:75731608 C/T cg19862616 chr7:65841803 NCRNA00174 0.61 8.63 0.42 2.43e-16 Eotaxin levels; LIHC cis rs829661 0.947 rs829665 chr2:30724701 T/A cg17749961 chr2:30669863 LCLAT1 0.97 9.37 0.45 1.01e-18 Midgestational circulating levels of PBDEs (fetal genetic effect); LIHC cis rs3806843 0.735 rs6849 chr5:140086191 G/T cg26395211 chr5:140044315 WDR55 0.41 5.97 0.31 5.94e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2845885 0.793 rs3751120 chr11:63884453 C/T cg19006947 chr11:64034861 PLCB3 -0.47 -7.36 -0.37 1.35e-12 Body mass index; LIHC cis rs6693567 0.874 rs698915 chr1:150388318 C/T cg18016565 chr1:150552671 MCL1 0.36 6.17 0.32 1.97e-9 Migraine; LIHC cis rs3806843 0.676 rs2245640 chr5:140029958 A/G cg16577123 chr5:140027231 NDUFA2;IK -0.41 -5.94 -0.31 7.18e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs8072100 0.967 rs4580230 chr17:45738861 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.4 -6.3 -0.32 9.22e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg00280220 chr17:61926910 NA 0.43 6.93 0.35 2.13e-11 Prudent dietary pattern; LIHC cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg13866156 chr1:1669148 SLC35E2 -0.7 -13.17 -0.58 2.47e-32 Body mass index; LIHC cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg19539972 chr4:7069911 GRPEL1 0.65 9.53 0.46 3.01e-19 Monocyte percentage of white cells; LIHC cis rs6942756 0.876 rs7789697 chr7:129060386 T/A cg02491457 chr7:128862824 NA -0.58 -8.99 -0.44 1.77e-17 White matter hyperintensity burden; LIHC cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1185460 0.565 rs584115 chr11:118938880 A/G cg01677386 chr11:118938358 VPS11 0.45 5.92 0.3 7.94e-9 Coronary artery disease; LIHC cis rs9916302 0.784 rs4795361 chr17:37573446 G/A cg03013999 chr17:37608204 MED1 0.35 5.74 0.3 2.09e-8 Glomerular filtration rate (creatinine); LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg14709524 chr16:89940631 TCF25 0.52 7.08 0.36 8.05e-12 Skin colour saturation; LIHC cis rs6545883 0.868 rs2518933 chr2:61797030 C/A cg14146966 chr2:61757674 XPO1 0.46 8.01 0.4 1.81e-14 Tuberculosis; LIHC cis rs7589728 0.514 rs78204719 chr2:88460747 G/C cg14558114 chr2:88469736 THNSL2 0.63 6.2 0.32 1.62e-9 Plasma clusterin levels; LIHC cis rs12497850 0.931 rs7643368 chr3:48992855 T/G cg07636037 chr3:49044803 WDR6 0.92 16.54 0.67 1.44e-45 Parkinson's disease; LIHC cis rs9549367 0.724 rs7985335 chr13:113869244 G/T cg00898013 chr13:113819073 PROZ 0.33 6.13 0.31 2.36e-9 Platelet distribution width; LIHC cis rs4654899 1.000 rs6703227 chr1:21374810 A/G cg08539965 chr1:21396338 EIF4G3 0.33 5.85 0.3 1.14e-8 Superior frontal gyrus grey matter volume; LIHC cis rs8103278 1.000 rs8108864 chr19:46301671 G/A cg11657440 chr19:46296263 DMWD -0.53 -8.35 -0.41 1.76e-15 Coronary artery disease; LIHC cis rs6582630 0.555 rs10880602 chr12:38505660 T/C cg26384229 chr12:38710491 ALG10B 0.66 9.54 0.46 2.87e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs2625529 0.824 rs16956452 chr15:72284092 T/C cg16672083 chr15:72433130 SENP8 -0.3 -5.78 -0.3 1.73e-8 Red blood cell count; LIHC cis rs807669 0.548 rs885978 chr22:19198226 A/G cg02655711 chr22:19163373 SLC25A1 0.34 5.87 0.3 1.04e-8 Metabolite levels; LIHC cis rs10979 0.965 rs9376758 chr6:143886878 G/A cg25407410 chr6:143891975 LOC285740 -0.36 -5.75 -0.3 2.02e-8 Hypospadias; LIHC cis rs8062405 0.755 rs62031607 chr16:28631530 A/T cg07451762 chr16:28383216 NA 0.41 7.03 0.36 1.16e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7312933 0.645 rs12049942 chr12:42587052 G/A cg01256987 chr12:42539512 GXYLT1 -0.41 -6.86 -0.35 3.33e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs765787 0.530 rs2899381 chr15:45529630 C/T cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.78 -0.3 1.71e-8 Uric acid levels; LIHC cis rs4797559 0.839 rs4797560 chr18:11583495 C/T cg14984255 chr18:11908827 MPPE1 0.33 5.77 0.3 1.8e-8 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs1555399 0.967 rs7161368 chr14:67983868 C/T cg16224230 chr14:67978224 TMEM229B -0.24 -5.91 -0.3 8.43e-9 Parkinson's disease; LIHC cis rs5769707 0.521 rs5769720 chr22:50062133 G/C cg07959070 chr22:50026188 C22orf34 -0.3 -7.19 -0.36 4.03e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs910316 0.687 rs175059 chr14:75490667 T/C cg11812906 chr14:75593930 NEK9 -0.73 -13.33 -0.58 6.34e-33 Height; LIHC cis rs7845219 0.539 rs13271644 chr8:95853948 A/G cg13393036 chr8:95962371 TP53INP1 -0.37 -8.12 -0.4 8.57e-15 Type 2 diabetes; LIHC cis rs9325144 0.510 rs6582599 chr12:38715965 T/G cg26384229 chr12:38710491 ALG10B 0.56 7.71 0.38 1.4e-13 Morning vs. evening chronotype; LIHC cis rs9902453 0.967 rs62070344 chr17:28476997 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.31 0.45 1.64e-18 Coffee consumption (cups per day); LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs4237845 0.537 rs7312623 chr12:58262523 G/T cg04478727 chr12:58166393 METTL1;FAM119B 0.58 8.05 0.4 1.43e-14 Intelligence (multi-trait analysis); LIHC cis rs10193935 0.901 rs10189710 chr2:42573102 C/G cg27598129 chr2:42591480 NA -0.74 -11.76 -0.54 4.69e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.08 0.44 9.16e-18 Platelet count; LIHC cis rs1448094 0.549 rs10863085 chr12:86236328 G/A cg02569458 chr12:86230093 RASSF9 0.49 6.51 0.33 2.68e-10 Major depressive disorder; LIHC cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.52 -7.28 -0.37 2.26e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs763121 0.886 rs1013339 chr22:38974680 C/T cg14440974 chr22:39074834 NA -0.35 -6.01 -0.31 4.79e-9 Menopause (age at onset); LIHC cis rs2204008 0.811 rs11525004 chr12:38333807 T/A cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.57e-15 Bladder cancer; LIHC cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs875971 0.862 rs10263690 chr7:65766453 G/C cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs6089584 0.627 rs55875402 chr20:60559925 G/A cg06108461 chr20:60628389 TAF4 -0.54 -7.35 -0.37 1.51e-12 Body mass index; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg10071602 chr16:2028740 TBL3 0.5 7.62 0.38 2.44e-13 Longevity; LIHC cis rs68170813 0.559 rs12532967 chr7:106937418 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs1185460 1.000 rs1799993 chr11:118958127 A/C cg23280166 chr11:118938394 VPS11 -0.51 -6.95 -0.35 1.87e-11 Coronary artery disease; LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg11070056 chr1:107600091 PRMT6 -0.66 -11.17 -0.52 6.77e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9399135 0.967 rs34546690 chr6:135369709 T/C cg24558204 chr6:135376177 HBS1L 0.44 7.14 0.36 5.58e-12 Red blood cell count; LIHC cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg06634786 chr22:41940651 POLR3H -0.79 -8.66 -0.42 1.96e-16 Vitiligo; LIHC cis rs34779708 0.931 rs2244100 chr10:35323636 G/A cg03585969 chr10:35415529 CREM -0.76 -11.44 -0.53 6.98e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7959452 0.901 rs1384 chr12:69747834 C/T cg20891283 chr12:69753455 YEATS4 0.7 11.96 0.54 8.91e-28 Blood protein levels; LIHC cis rs7100689 0.622 rs1340373 chr10:82129250 G/A cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs6570726 0.934 rs430003 chr6:145819506 C/T cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg12064134 chr16:90016061 DEF8 -0.47 -6.15 -0.32 2.19e-9 Skin colour saturation; LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.45 7.02 0.35 1.2e-11 Prudent dietary pattern; LIHC cis rs17666538 0.585 rs1669733 chr8:606696 C/T cg02524346 chr8:600233 NA -0.79 -6.51 -0.33 2.68e-10 IgG glycosylation; LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg12516959 chr21:47718080 NA -0.36 -5.96 -0.31 6.14e-9 Testicular germ cell tumor; LIHC cis rs1008375 1.000 rs7671752 chr4:17661398 C/T cg02297831 chr4:17616191 MED28 0.43 6.75 0.34 6.38e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17345786 0.906 rs59359251 chr3:101146362 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.57 7.16 0.36 4.83e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs3770081 1.000 rs2303340 chr2:86333193 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.87 -9.77 -0.47 4.65e-20 Facial emotion recognition (sad faces); LIHC cis rs853679 0.517 rs1853097 chr6:28058635 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs3020736 0.500 rs28791586 chr22:42500483 A/G cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs1008375 1.000 rs10011865 chr4:17645710 G/A cg16339924 chr4:17578868 LAP3 0.44 6.28 0.32 1.04e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3806843 0.735 rs801183 chr5:140091115 C/T cg16179182 chr5:140090404 VTRNA1-1 -0.38 -6.32 -0.32 8.14e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7945705 0.967 rs34842234 chr11:8891894 G/A cg12365402 chr11:9010492 NRIP3 0.29 7.54 0.38 4.21e-13 Hemoglobin concentration; LIHC cis rs9560113 1.000 rs9560103 chr13:112174253 G/A cg14154082 chr13:112174009 NA 0.29 6.1 0.31 2.81e-9 Menarche (age at onset); LIHC cis rs4474465 0.850 rs10751292 chr11:78242201 C/G cg27205649 chr11:78285834 NARS2 0.4 6.2 0.32 1.65e-9 Alzheimer's disease (survival time); LIHC cis rs4820539 0.966 rs5759600 chr22:23483769 C/A cg21100191 chr22:23484243 RTDR1 0.9 16.53 0.67 1.53e-45 Bone mineral density; LIHC cis rs9325144 0.555 rs1813392 chr12:38692203 C/T cg26384229 chr12:38710491 ALG10B -0.53 -7.66 -0.38 1.93e-13 Morning vs. evening chronotype; LIHC cis rs11098499 0.863 rs11723090 chr4:120490592 T/C cg09307838 chr4:120376055 NA 0.75 11.85 0.54 2.2e-27 Corneal astigmatism; LIHC cis rs9911578 0.967 rs6416932 chr17:57148991 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -8.99 -0.44 1.67e-17 Intelligence (multi-trait analysis); LIHC cis rs595982 0.702 rs626974 chr19:49375900 T/C cg21252483 chr19:49399788 TULP2 -0.46 -7.67 -0.38 1.85e-13 Red cell distribution width; LIHC cis rs6964587 0.626 rs6979235 chr7:91511776 T/C cg17063962 chr7:91808500 NA -0.61 -10.95 -0.51 4.15e-24 Breast cancer; LIHC trans rs9388451 0.874 rs3734634 chr6:126111800 G/A cg05039488 chr6:79577232 IRAK1BP1 -0.53 -8.56 -0.42 3.94e-16 Brugada syndrome; LIHC cis rs2120019 1.000 rs2083731 chr15:75368538 A/C cg11632617 chr15:75315747 PPCDC -0.43 -6.26 -0.32 1.15e-9 Blood trace element (Zn levels); LIHC cis rs2455799 0.593 rs13078487 chr3:15929590 G/T cg12698662 chr3:15914712 MIR563 -0.36 -6.82 -0.35 4.07e-11 Mean platelet volume; LIHC cis rs4665809 0.549 rs7577896 chr2:26524493 C/T cg04944784 chr2:26401820 FAM59B 0.57 5.87 0.3 1.04e-8 Gut microbiome composition (summer); LIHC cis rs2204008 0.902 rs11520218 chr12:38223227 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.72 0.5 2.64e-23 Bladder cancer; LIHC trans rs800082 1.000 rs7613909 chr3:144308606 A/G cg24215973 chr2:240111563 HDAC4 0.51 7.56 0.38 3.76e-13 Smoking behavior; LIHC cis rs12586317 0.513 rs74564132 chr14:35472882 C/T cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.03e-32 Psoriasis; LIHC cis rs1552244 0.626 rs2886396 chr3:10037670 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs17125944 0.505 rs75194546 chr14:53212069 A/C cg00686598 chr14:53173677 PSMC6 1.29 15.79 0.65 1.44e-42 Alzheimer's disease (late onset); LIHC cis rs10791097 0.694 rs4264159 chr11:130755784 G/T cg22079354 chr11:130786696 SNX19 0.41 5.76 0.3 1.84e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs801193 0.569 rs13242290 chr7:66121885 G/A cg18252515 chr7:66147081 NA 0.47 6.97 0.35 1.62e-11 Aortic root size; LIHC cis rs6456156 0.792 rs9366089 chr6:167512896 A/G cg07741184 chr6:167504864 NA 0.28 6.82 0.35 4.09e-11 Primary biliary cholangitis; LIHC cis rs7395581 0.918 rs1055510 chr11:47292237 A/G cg25783544 chr11:47291846 MADD 0.43 6.27 0.32 1.1e-9 HDL cholesterol; LIHC cis rs907683 0.570 rs2666104 chr2:220281010 C/T cg15015639 chr2:220282977 DES -0.32 -7.61 -0.38 2.64e-13 Resting heart rate; LIHC cis rs6089584 1.000 rs6089580 chr20:60558976 G/A cg13770153 chr20:60521292 NA -0.35 -6.9 -0.35 2.53e-11 Body mass index; LIHC cis rs1185460 0.934 rs10892328 chr11:118942654 T/A cg23280166 chr11:118938394 VPS11 0.55 7.04 0.36 1.04e-11 Coronary artery disease; LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg00656387 chr3:40428638 ENTPD3 0.49 8.34 0.41 1.81e-15 Renal cell carcinoma; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.19 -0.32 1.71e-9 Total body bone mineral density; LIHC cis rs1552244 0.554 rs55847233 chr3:9991101 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.52 -8.44 -0.42 9.2e-16 Alzheimer's disease; LIHC cis rs3741404 0.931 rs594942 chr11:64006292 T/C cg04317338 chr11:64019027 PLCB3 -0.55 -7.48 -0.37 6.53e-13 Platelet count; LIHC cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg11890956 chr21:40555474 PSMG1 1.07 15.39 0.64 5.41e-41 Cognitive function; LIHC cis rs1552244 0.882 rs13084194 chr3:10031492 T/A cg08888203 chr3:10149979 C3orf24 0.49 6.07 0.31 3.45e-9 Alzheimer's disease; LIHC cis rs16866061 0.888 rs6748341 chr2:225377574 C/G cg12698349 chr2:225449008 CUL3 0.79 13.49 0.59 1.48e-33 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs2625529 0.642 rs2200056 chr15:72302667 T/C cg16672083 chr15:72433130 SENP8 -0.3 -5.73 -0.3 2.24e-8 Red blood cell count; LIHC cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg11644478 chr21:40555479 PSMG1 -0.4 -6.16 -0.32 2.01e-9 Cognitive function; LIHC trans rs792448 0.743 rs351379 chr1:212423789 G/T cg20223728 chr6:6006398 NRN1 0.35 6.12 0.31 2.51e-9 White blood cell count (basophil); LIHC cis rs4936323 0.504 rs10891812 chr11:115096431 T/C cg04055981 chr11:115044050 NA 0.37 5.91 0.3 8.27e-9 Response to cytadine analogues (cytosine arabinoside); LIHC cis rs7208859 0.673 rs3764421 chr17:29167653 A/C cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs3780486 0.757 rs10121987 chr9:33119818 A/G cg20290983 chr6:43655470 MRPS18A 1.18 30.04 0.85 5.97e-98 IgG glycosylation; LIHC cis rs9905704 0.647 rs11652713 chr17:57079742 C/T cg12560992 chr17:57184187 TRIM37 0.6 9.08 0.44 9.03e-18 Testicular germ cell tumor; LIHC cis rs9309473 0.950 rs6735946 chr2:73790058 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.94e-10 Metabolite levels; LIHC cis rs2404602 0.583 rs3759853 chr15:76587777 C/T cg22467129 chr15:76604101 ETFA -0.39 -6.44 -0.33 4e-10 Blood metabolite levels; LIHC cis rs62103177 0.535 rs4799109 chr18:77675188 A/T cg20368463 chr18:77673604 PQLC1 0.55 6.85 0.35 3.45e-11 Opioid sensitivity; LIHC cis rs16828019 0.777 rs35044078 chr1:41474400 C/G cg03387723 chr1:41708464 SCMH1 -0.4 -6.25 -0.32 1.25e-9 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.586 rs2864882 chr1:150883037 C/T cg15448220 chr1:150897856 SETDB1 0.39 6.18 0.32 1.88e-9 Melanoma; LIHC cis rs11785400 1.000 rs6995314 chr8:143749718 A/G cg10596483 chr8:143751796 JRK -0.53 -8.51 -0.42 5.69e-16 Schizophrenia; LIHC cis rs12699477 0.545 rs117125814 chr7:1910681 T/G cg04267008 chr7:1944627 MAD1L1 -0.61 -9.44 -0.45 5.88e-19 Testicular germ cell tumor; LIHC cis rs7712401 0.791 rs4836244 chr5:122116232 A/G cg18764291 chr5:122110994 SNX2 0.37 6.36 0.33 6.38e-10 Mean platelet volume; LIHC cis rs11663156 1.000 rs72933414 chr18:50929489 C/T cg24270629 chr18:50823537 DCC -0.48 -6.59 -0.34 1.67e-10 Intelligence (multi-trait analysis); LIHC cis rs244293 0.965 rs244290 chr17:53231231 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.33 -0.37 1.65e-12 Menarche (age at onset); LIHC cis rs6121246 0.567 rs7266471 chr20:30220599 T/A cg13852791 chr20:30311386 BCL2L1 0.78 6.77 0.34 5.69e-11 Mean corpuscular hemoglobin; LIHC cis rs2070488 1.000 rs3792527 chr3:38493212 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC cis rs12477438 0.539 rs720228 chr2:99704547 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 23.98 0.79 3.01e-75 Chronic sinus infection; LIHC cis rs7075426 0.716 rs11598718 chr10:88294484 G/A cg07322936 chr10:88137208 NA 0.49 6.31 0.32 8.75e-10 Migraine without aura; LIHC cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg05896524 chr21:47604654 C21orf56 0.48 7.4 0.37 1.03e-12 Testicular germ cell tumor; LIHC cis rs4638749 0.734 rs4676191 chr2:108861242 A/G cg06795125 chr2:108905320 SULT1C2 -0.3 -6.0 -0.31 5.15e-9 Blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11087358 chr12:57940980 DCTN2 0.43 6.15 0.32 2.2e-9 Pancreatic cancer; LIHC cis rs7845219 0.544 rs34293080 chr8:95908078 G/T cg16049864 chr8:95962084 TP53INP1 -0.45 -6.71 -0.34 8.33e-11 Type 2 diabetes; LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.54 0.8 2.06e-77 Prudent dietary pattern; LIHC cis rs9303401 0.659 rs35928756 chr17:56702652 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs703842 0.532 rs238516 chr12:58117355 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.68 -0.34 9.6e-11 Multiple sclerosis; LIHC cis rs798554 0.644 rs1639040 chr7:2884116 G/T cg13628971 chr7:2884303 GNA12 0.6 10.11 0.48 3.5e-21 Height; LIHC cis rs11971779 0.680 rs6467837 chr7:139023575 A/G cg07862535 chr7:139043722 LUC7L2 0.58 10.01 0.48 7.65e-21 Diisocyanate-induced asthma; LIHC cis rs2346177 0.844 rs12991646 chr2:46643831 A/G cg02822958 chr2:46747628 ATP6V1E2 0.41 6.31 0.32 8.7e-10 HDL cholesterol; LIHC cis rs2346177 0.519 rs13003074 chr2:46671420 A/T cg02822958 chr2:46747628 ATP6V1E2 -0.47 -7.42 -0.37 9.14e-13 HDL cholesterol; LIHC cis rs8044995 0.925 rs9928653 chr16:68252079 T/C cg05110241 chr16:68378359 PRMT7 -0.51 -6.07 -0.31 3.45e-9 Schizophrenia; LIHC cis rs2243480 1.000 rs160652 chr7:65538431 A/G cg12463550 chr7:65579703 CRCP 0.69 7.23 0.36 3.24e-12 Diabetic kidney disease; LIHC cis rs77741769 0.571 rs4454799 chr12:121317075 A/C cg02419362 chr12:121203948 SPPL3 -0.33 -5.8 -0.3 1.5e-8 Mean corpuscular volume; LIHC cis rs3736485 0.808 rs28485410 chr15:51949885 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.02 -0.31 4.4e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8062405 0.755 rs17640009 chr16:28595700 A/G cg00204512 chr16:28754710 NA 0.4 6.92 0.35 2.29e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10464366 0.544 rs953874 chr7:39147916 G/A cg20302533 chr7:39170763 POU6F2 0.36 6.67 0.34 1.01e-10 IgG glycosylation; LIHC cis rs2574704 0.781 rs2616556 chr3:11659990 T/C cg15876825 chr3:11651881 VGLL4 0.49 7.9 0.39 3.94e-14 Body mass index; LIHC cis rs9517320 0.515 rs61969456 chr13:99174799 C/G cg07423050 chr13:99094983 FARP1 -0.5 -8.76 -0.43 9.11e-17 Longevity; LIHC cis rs12477438 1.000 rs57846982 chr2:99921574 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.99 -11.77 -0.54 4.56e-27 Chronic sinus infection; LIHC cis rs6500602 0.702 rs6500606 chr16:4502514 A/G cg04083430 chr16:4736063 MGRN1 0.41 5.74 0.3 2.12e-8 Schizophrenia; LIHC cis rs507506 0.771 rs929229 chr17:7105399 C/T cg25256661 chr17:7137939 DVL2 0.53 8.38 0.41 1.34e-15 Adiponectin levels; LIHC cis rs17401966 1.000 rs4846208 chr1:10313839 T/C cg15208524 chr1:10270712 KIF1B 0.45 6.44 0.33 4.13e-10 Hepatocellular carcinoma; LIHC cis rs6960043 0.818 rs13220985 chr7:15062694 A/G cg19272540 chr7:15055459 NA 0.25 6.76 0.34 6.04e-11 Type 2 diabetes; LIHC cis rs11098499 0.754 rs1980027 chr4:120251577 C/T cg09307838 chr4:120376055 NA 0.71 11.14 0.52 8.4e-25 Corneal astigmatism; LIHC cis rs644799 0.965 rs607039 chr11:95547086 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs9929218 1.000 rs8056538 chr16:68802282 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.54 -8.12 -0.4 8.63e-15 Colorectal cancer; LIHC trans rs875971 0.545 rs73148639 chr7:65855329 A/T cg26939375 chr7:64535504 NA 0.4 6.43 0.33 4.37e-10 Aortic root size; LIHC trans rs13325613 0.834 rs13092160 chr3:46254791 A/G cg24700663 chr4:77172643 FAM47E 0.54 6.15 0.32 2.12e-9 Monocyte count; LIHC cis rs3806843 0.735 rs801180 chr5:140092903 G/T cg19875535 chr5:140030758 IK -0.41 -6.82 -0.35 4.16e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs12464559 0.522 rs4414677 chr2:152624932 A/C cg01189475 chr2:152685088 ARL5A -0.65 -7.84 -0.39 5.76e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs16828019 0.852 rs3820090 chr1:41573652 A/G cg03387723 chr1:41708464 SCMH1 -0.43 -6.95 -0.35 1.8e-11 Intelligence (multi-trait analysis); LIHC cis rs11671005 0.735 rs34152946 chr19:58923263 C/T cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs7208859 0.673 rs9907197 chr17:29018263 C/T cg14067834 chr17:29058358 SUZ12P 0.57 6.04 0.31 3.99e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2153535 0.541 rs4637688 chr6:8446501 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.66 0.53 1.09e-26 Motion sickness; LIHC cis rs1707322 0.648 rs4439382 chr1:46150805 C/T cg03146154 chr1:46216737 IPP 0.58 9.65 0.46 1.23e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7107174 1.000 rs1893448 chr11:77969180 G/A cg02023728 chr11:77925099 USP35 0.45 8.76 0.43 9.18e-17 Testicular germ cell tumor; LIHC cis rs2412488 0.927 rs7689981 chr4:54314828 A/G cg22241045 chr4:54363911 LNX1 -0.42 -6.79 -0.34 4.97e-11 DNA methylation (variation); LIHC cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg13866156 chr1:1669148 SLC35E2 -0.66 -12.42 -0.56 1.77e-29 Body mass index; LIHC cis rs1348850 0.574 rs10195917 chr2:178443121 C/T cg27490568 chr2:178487706 NA 0.74 9.18 0.44 4.2e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs3008870 0.583 rs2815369 chr1:67500894 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.88 13.16 0.58 2.85e-32 Lymphocyte percentage of white cells; LIHC cis rs12497850 0.863 rs4974084 chr3:48939080 G/A cg06212747 chr3:49208901 KLHDC8B 0.55 7.07 0.36 8.95e-12 Parkinson's disease; LIHC cis rs11252926 0.528 rs11252090 chr10:436547 C/T cg18196295 chr10:418757 DIP2C -0.4 -5.94 -0.31 7.09e-9 Psychosis in Alzheimer's disease; LIHC cis rs9503598 0.644 rs4959240 chr6:3430674 C/T cg00476032 chr6:3446245 SLC22A23 0.34 6.46 0.33 3.53e-10 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg26308932 chr13:114088860 ADPRHL1 0.42 6.19 0.32 1.7e-9 Longevity; LIHC cis rs7552404 0.961 rs448710 chr1:76116554 T/C cg22875332 chr1:76189707 ACADM -0.49 -7.3 -0.37 2.08e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs709400 0.832 rs10145755 chr14:104121984 C/T cg26031613 chr14:104095156 KLC1 1.06 14.36 0.61 6.26e-37 Body mass index; LIHC cis rs17539620 0.624 rs117591255 chr6:154839118 G/A cg17771515 chr6:154831774 CNKSR3 0.58 6.08 0.31 3.14e-9 Lipoprotein (a) levels; LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg20302342 chr1:156215951 PAQR6 0.33 6.29 0.32 9.57e-10 Tonsillectomy; LIHC cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg06873352 chr17:61820015 STRADA -0.54 -8.77 -0.43 8.66e-17 Prudent dietary pattern; LIHC cis rs9309473 0.898 rs28879089 chr2:73812886 G/A cg20560298 chr2:73613845 ALMS1 -0.56 -6.58 -0.34 1.72e-10 Metabolite levels; LIHC cis rs8072100 0.934 rs9905583 chr17:45741016 C/T cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.36 -5.78 -0.3 1.68e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs4714291 0.832 rs1524087 chr6:40057504 A/G cg02267698 chr19:7991119 CTXN1 -0.4 -6.85 -0.35 3.5e-11 Strep throat; LIHC cis rs5769765 0.908 rs9616213 chr22:50317851 T/G cg02269571 chr22:50332266 NA -0.66 -9.07 -0.44 9.23e-18 Schizophrenia; LIHC cis rs11122272 0.735 rs2474634 chr1:231487017 T/C cg06096015 chr1:231504339 EGLN1 0.5 9.31 0.45 1.54e-18 Hemoglobin concentration; LIHC cis rs7917772 0.582 rs10748826 chr10:104354804 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11098499 0.954 rs4345162 chr4:120312959 G/A cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs11971779 0.680 rs73154134 chr7:139039951 G/A cg07862535 chr7:139043722 LUC7L2 0.66 10.45 0.49 2.22e-22 Diisocyanate-induced asthma; LIHC cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg26874164 chr19:58962979 ZNF324B 0.59 9.06 0.44 1.03e-17 Uric acid clearance; LIHC trans rs1728785 0.901 rs1183956 chr16:68606726 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs10791323 0.569 rs2187450 chr11:133743792 A/G cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.58e-9 Childhood ear infection; LIHC cis rs1401454 1.000 rs1837095 chr11:16245692 T/A cg02656851 chr11:16430247 SOX6 -0.32 -6.11 -0.31 2.66e-9 Blood pressure; LIHC cis rs9783347 1.000 rs9783386 chr11:18386625 G/A cg15585147 chr11:18324498 HPS5 0.43 6.55 0.33 2.09e-10 Pancreatic cancer; LIHC cis rs651907 0.557 rs34947019 chr3:101532235 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.68 11.31 0.52 2.13e-25 Colorectal cancer; LIHC cis rs10791323 0.598 rs10750550 chr11:133736083 A/G cg06766960 chr11:133703094 NA -0.46 -6.95 -0.35 1.89e-11 Childhood ear infection; LIHC cis rs1005277 0.602 rs1780141 chr10:38504299 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg05484376 chr2:27715224 FNDC4 0.38 6.35 0.32 6.88e-10 Total body bone mineral density; LIHC cis rs941873 0.868 rs12780295 chr10:81115438 G/A cg09469691 chr10:81107165 PPIF 0.67 10.26 0.49 1e-21 Height; LIHC cis rs7116495 0.881 rs680150 chr11:71605507 T/A cg26138937 chr11:71823887 C11orf51 0.68 6.85 0.35 3.52e-11 Severe influenza A (H1N1) infection; LIHC cis rs2625529 0.824 rs35167572 chr15:72378960 A/G cg16672083 chr15:72433130 SENP8 -0.31 -5.86 -0.3 1.06e-8 Red blood cell count; LIHC cis rs1538970 0.962 rs9429158 chr1:45821393 A/G cg24296786 chr1:45957014 TESK2 -0.5 -7.63 -0.38 2.36e-13 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16527491 chr14:38065127 FOXA1 0.48 6.5 0.33 2.85e-10 Lung function (FEV1/FVC); LIHC trans rs6058796 1.000 rs13036962 chr20:31239010 T/C cg02600331 chr11:130417168 NA 0.38 7.38 0.37 1.25e-12 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs10744422 1.000 rs7139055 chr12:123364198 A/G cg18912006 chr12:123335444 HIP1R 0.62 7.28 0.37 2.31e-12 Schizophrenia; LIHC cis rs7659604 0.537 rs6823818 chr4:122731699 G/C cg19748678 chr4:122722346 EXOSC9 0.67 11.07 0.51 1.47e-24 Type 2 diabetes; LIHC cis rs7927592 0.871 rs12941 chr11:68382193 C/T cg16797656 chr11:68205561 LRP5 0.49 7.71 0.38 1.39e-13 Total body bone mineral density; LIHC cis rs7927771 0.832 rs4752990 chr11:47410393 G/A cg20135002 chr11:47629003 NA -0.55 -9.17 -0.44 4.67e-18 Subjective well-being; LIHC trans rs12478296 0.591 rs12719765 chr2:242997202 C/G cg01596870 chr19:55963115 NA -0.69 -10.46 -0.49 2.19e-22 Obesity-related traits; LIHC cis rs8072100 0.576 rs7216112 chr17:45406345 C/T cg08085267 chr17:45401833 C17orf57 0.59 8.29 0.41 2.69e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg24879335 chr3:133465180 TF 0.28 6.36 0.33 6.59e-10 Iron status biomarkers; LIHC cis rs7903847 0.642 rs7084654 chr10:99135262 G/A cg06359132 chr10:99160096 RRP12 -0.42 -6.6 -0.34 1.57e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2242116 0.761 rs6780601 chr3:46965856 A/G cg27129171 chr3:47204927 SETD2 0.55 8.86 0.43 4.3e-17 Birth weight; LIHC cis rs611744 0.870 rs613261 chr8:109165949 A/G cg21045802 chr8:109455806 TTC35 0.57 9.86 0.47 2.31e-20 Dupuytren's disease; LIHC trans rs875971 0.895 rs778700 chr7:65866450 C/T cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs477692 0.905 rs4751106 chr10:131424653 G/T cg19680672 chr10:131412579 MGMT 0.41 6.4 0.33 5.26e-10 Response to temozolomide; LIHC cis rs506338 0.517 rs516117 chr11:64433444 T/C cg27209729 chr11:64428925 NRXN2 0.35 6.57 0.33 1.9e-10 Body mass index;Urate levels; LIHC cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.47 -6.69 -0.34 8.98e-11 Gut microbiome composition (summer); LIHC cis rs9814567 1.000 rs62271515 chr3:134300507 T/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.12 -0.31 2.57e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs10411161 0.810 rs57171871 chr19:52385332 T/C cg22319618 chr22:45562946 NUP50 -0.59 -7.01 -0.35 1.28e-11 Breast cancer; LIHC cis rs1443512 0.812 rs2044210 chr12:54335533 C/G cg12374095 chr12:54320830 NA 0.42 6.06 0.31 3.67e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs6951245 0.935 rs79067319 chr7:1065548 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -6.02 -0.31 4.58e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs950169 0.580 rs62021208 chr15:85196244 G/A cg12863693 chr15:85201151 NMB 0.48 7.01 0.35 1.27e-11 Schizophrenia; LIHC cis rs6964587 1.000 rs2299239 chr7:91654617 C/T cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg22800045 chr5:56110881 MAP3K1 -0.58 -6.91 -0.35 2.33e-11 Initial pursuit acceleration; LIHC trans rs1005277 0.579 rs2474563 chr10:38375938 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 9.06 0.44 1.04e-17 Platelet count; LIHC cis rs950169 0.922 rs12911223 chr15:84831671 G/A cg03959625 chr15:84868606 LOC388152 -0.44 -6.47 -0.33 3.31e-10 Schizophrenia; LIHC cis rs10870270 1.000 rs4880263 chr10:133787629 C/T cg17892150 chr10:133769511 PPP2R2D -0.67 -12.35 -0.56 3.21e-29 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs3204270 0.543 rs34034499 chr17:79638568 G/C cg18367735 chr17:79674897 NA 0.64 7.61 0.38 2.66e-13 Dental caries; LIHC cis rs713477 0.617 rs11627405 chr14:55911657 T/C cg13175173 chr14:55914753 NA -0.3 -6.73 -0.34 7.38e-11 Pediatric bone mineral content (femoral neck); LIHC trans rs1814175 0.616 rs10839349 chr11:49753748 C/A cg18944383 chr4:111397179 ENPEP 0.28 7.07 0.36 8.67e-12 Height; LIHC cis rs9790314 0.613 rs1447620 chr3:160616211 T/C cg03342759 chr3:160939853 NMD3 0.56 7.33 0.37 1.63e-12 Morning vs. evening chronotype; LIHC cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg06238570 chr21:40685208 BRWD1 -0.38 -6.09 -0.31 3.05e-9 Menarche (age at onset); LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg03874509 chr1:107600012 PRMT6 0.67 9.92 0.47 1.47e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs727563 0.594 rs132807 chr22:42071584 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.56 0.5 9.87e-23 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg10802521 chr3:52805072 NEK4 -0.44 -7.24 -0.36 2.92e-12 Bipolar disorder; LIHC cis rs5769765 0.908 rs9616396 chr22:50317825 T/C cg09182678 chr22:50328711 NA -0.39 -5.82 -0.3 1.34e-8 Schizophrenia; LIHC cis rs3823572 0.564 rs2971983 chr7:133652537 A/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.76 -0.3 1.89e-8 Intelligence (multi-trait analysis); LIHC cis rs9926296 0.715 rs2115401 chr16:89740609 A/G cg03605463 chr16:89740564 NA -0.46 -7.24 -0.36 2.96e-12 Vitiligo; LIHC cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg13607699 chr17:42295918 UBTF 0.44 7.1 0.36 7.46e-12 Total body bone mineral density; LIHC cis rs644799 0.710 rs3748253 chr11:95519506 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.74 0.57 1.07e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs858239 0.539 rs10279194 chr7:23191083 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.83 0.35 3.89e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs1113500 0.933 rs11185256 chr1:108633957 C/T cg06207961 chr1:108661230 NA 0.38 7.48 0.37 6.47e-13 Growth-regulated protein alpha levels; LIHC cis rs10463316 0.817 rs58892766 chr5:150776115 T/C cg03212797 chr5:150827313 SLC36A1 -0.41 -6.22 -0.32 1.47e-9 Metabolite levels (Pyroglutamine); LIHC cis rs6952808 0.743 rs10266703 chr7:1918941 C/A cg02951883 chr7:2050386 MAD1L1 -0.55 -8.0 -0.4 1.97e-14 Bipolar disorder and schizophrenia; LIHC cis rs9457247 0.967 rs430145 chr6:167410369 C/T cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC cis rs7223966 1.000 rs61360320 chr17:61800392 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.96 0.35 1.72e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6089584 0.888 rs6061966 chr20:60607936 C/G cg06108461 chr20:60628389 TAF4 -1.01 -17.29 -0.68 1.44e-48 Body mass index; LIHC cis rs7927592 0.956 rs7113287 chr11:68372186 A/T cg20283391 chr11:68216788 NA -0.53 -8.05 -0.4 1.35e-14 Total body bone mineral density; LIHC cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg03806693 chr22:41940476 POLR3H -0.99 -10.44 -0.49 2.57e-22 Vitiligo; LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg14159672 chr1:205819179 PM20D1 0.73 10.31 0.49 7.04e-22 Menarche (age at onset); LIHC cis rs6570726 0.935 rs390252 chr6:145856896 A/G cg23711669 chr6:146136114 FBXO30 0.56 10.03 0.48 6.55e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg27170947 chr2:26402098 FAM59B -0.67 -8.2 -0.41 4.95e-15 Gut microbiome composition (summer); LIHC cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg08392591 chr16:89556376 ANKRD11 -0.47 -7.41 -0.37 9.73e-13 Multiple myeloma (IgH translocation); LIHC cis rs2730245 1.000 rs6965685 chr7:158726462 C/T cg24397884 chr7:158709396 WDR60 0.41 6.37 0.33 5.99e-10 Height; LIHC cis rs2354432 0.556 rs4424557 chr1:146871119 A/G cg25205988 chr1:146714368 CHD1L 0.77 8.6 0.42 2.82e-16 Mitochondrial DNA levels; LIHC cis rs6723226 0.593 rs176401 chr2:32636511 A/T cg02381751 chr2:32503542 YIPF4 -0.7 -10.71 -0.5 2.86e-23 Intelligence (multi-trait analysis); LIHC cis rs17253792 0.822 rs78386830 chr14:56069224 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs6545883 0.965 rs778752 chr2:61776902 C/G cg14146966 chr2:61757674 XPO1 0.47 8.29 0.41 2.54e-15 Tuberculosis; LIHC trans rs11098499 0.863 rs1383532 chr4:120434404 A/T cg25214090 chr10:38739885 LOC399744 -0.59 -9.8 -0.47 3.93e-20 Corneal astigmatism; LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg07157834 chr1:205819609 PM20D1 0.77 11.41 0.53 8.73e-26 Menarche (age at onset); LIHC cis rs2777491 0.507 rs11854081 chr15:41646398 C/T cg18705301 chr15:41695430 NDUFAF1 -1.24 -18.41 -0.71 4.36e-53 Ulcerative colitis; LIHC cis rs1866706 0.896 rs4757955 chr11:12876492 C/A cg25843174 chr11:12811716 TEAD1 -0.28 -6.01 -0.31 4.78e-9 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.701 rs11582413 chr1:231530098 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs7903847 0.642 rs11189192 chr10:99149403 G/A cg06359132 chr10:99160096 RRP12 -0.42 -6.47 -0.33 3.3e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1403694 0.695 rs5029969 chr3:186434405 G/T cg12454167 chr3:186435060 KNG1 0.38 8.97 0.44 2.01e-17 Blood protein levels; LIHC cis rs17376456 0.825 rs35496867 chr5:93220400 T/C cg25358565 chr5:93447407 FAM172A 1.03 9.23 0.45 2.94e-18 Diabetic retinopathy; LIHC cis rs116975820 0.601 rs11181393 chr12:42657902 A/G cg01256987 chr12:42539512 GXYLT1 -0.53 -5.75 -0.3 2e-8 PR interval in Tripanosoma cruzi seropositivity; LIHC cis rs473651 0.935 rs520765 chr2:239354712 C/T cg21699342 chr2:239360505 ASB1 0.36 6.89 0.35 2.71e-11 Multiple system atrophy; LIHC trans rs4566357 0.615 rs10178260 chr2:227914458 G/T cg16088116 chr21:44841560 SIK1 -0.41 -6.39 -0.33 5.52e-10 Coronary artery disease; LIHC cis rs6088580 0.634 rs6088478 chr20:32971719 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.34 -0.58 5.73e-33 Glomerular filtration rate (creatinine); LIHC cis rs7412746 0.646 rs10399947 chr1:150861960 G/A cg18016565 chr1:150552671 MCL1 0.49 9.49 0.46 4.11e-19 Melanoma; LIHC trans rs867371 0.929 rs1045508 chr15:82449906 A/C cg18393722 chr15:85113863 UBE2QP1 0.44 7.66 0.38 1.91e-13 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs2075165 0.901 rs1804999 chr1:156219450 A/G cg10096929 chr1:156261403 TMEM79 0.37 6.01 0.31 4.73e-9 Tonsillectomy; LIHC trans rs13381277 0.850 rs9948412 chr18:74329454 A/C cg17352830 chr21:37617589 DOPEY2 -0.55 -6.4 -0.33 5e-10 Dental caries; LIHC cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.05e-17 Bipolar disorder; LIHC cis rs5753037 0.676 rs6006267 chr22:30216982 C/A cg01021169 chr22:30184971 ASCC2 -0.41 -8.2 -0.41 4.74e-15 Type 1 diabetes; LIHC cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg24642844 chr7:1081250 C7orf50 -0.6 -6.53 -0.33 2.37e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7927592 0.731 rs11228288 chr11:68353550 A/G cg20283391 chr11:68216788 NA -0.38 -6.05 -0.31 3.85e-9 Total body bone mineral density; LIHC cis rs7937890 0.504 rs2575847 chr11:14471172 C/T cg02886208 chr11:14281011 SPON1 -0.46 -6.58 -0.34 1.75e-10 Mitochondrial DNA levels; LIHC cis rs8028182 0.583 rs9944207 chr15:75912889 A/T cg20655648 chr15:75932815 IMP3 0.46 6.51 0.33 2.67e-10 Sudden cardiac arrest; LIHC cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg11062466 chr8:58055876 NA 0.51 6.95 0.35 1.87e-11 Developmental language disorder (linguistic errors); LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.59 11.11 0.51 1.11e-24 Prudent dietary pattern; LIHC cis rs250677 0.958 rs10056942 chr5:148416114 C/A cg18129178 chr5:148520854 ABLIM3 -0.47 -6.38 -0.33 5.75e-10 Breast cancer; LIHC cis rs57244997 0.582 rs73030429 chr6:162438902 A/G cg17173639 chr6:162384350 PARK2 -0.52 -6.79 -0.34 5.09e-11 Mosquito bite size; LIHC cis rs28830936 0.966 rs28373318 chr15:42126725 C/T cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.8 -0.3 1.51e-8 Diastolic blood pressure; LIHC cis rs11673344 0.523 rs10420330 chr19:37602171 G/A cg27390819 chr19:37464633 NA -0.43 -5.79 -0.3 1.61e-8 Obesity-related traits; LIHC cis rs10089 0.904 rs2195921 chr5:127489754 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.61 0.34 1.51e-10 Ileal carcinoids; LIHC cis rs898097 0.845 rs7213006 chr17:80899928 T/C cg15664640 chr17:80829946 TBCD 0.57 9.3 0.45 1.72e-18 Breast cancer; LIHC cis rs7572733 0.555 rs10202569 chr2:198934726 C/G cg03934865 chr2:198174659 NA 0.43 6.04 0.31 3.95e-9 Dermatomyositis; LIHC cis rs9916302 0.904 rs8081338 chr17:37406139 C/T cg00129232 chr17:37814104 STARD3 -0.41 -6.54 -0.33 2.22e-10 Glomerular filtration rate (creatinine); LIHC cis rs1003719 0.715 rs2835646 chr21:38546574 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs4563143 0.704 rs16961809 chr19:29226299 C/T cg12756686 chr19:29218302 NA 0.42 7.14 0.36 5.61e-12 Methadone dose in opioid dependence; LIHC trans rs1005277 0.522 rs289645 chr10:37943642 T/C cg17830980 chr10:43048298 ZNF37B -0.42 -8.06 -0.4 1.31e-14 Extrinsic epigenetic age acceleration; LIHC cis rs17253792 0.545 rs12886406 chr14:56027605 G/A cg01858014 chr14:56050164 KTN1 -0.74 -6.58 -0.34 1.72e-10 Putamen volume; LIHC cis rs8062405 1.000 rs62037371 chr16:28890131 C/A cg00204512 chr16:28754710 NA 0.34 6.26 0.32 1.15e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs780094 0.544 rs780110 chr2:27685388 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.56 -0.33 1.99e-10 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs35110281 0.720 rs162394 chr21:44943550 C/G cg01579765 chr21:45077557 HSF2BP 0.33 6.14 0.32 2.3e-9 Mean corpuscular volume; LIHC cis rs909002 0.772 rs6681414 chr1:32070234 G/A cg13919466 chr1:32135498 COL16A1 -0.32 -6.15 -0.32 2.16e-9 Intelligence (multi-trait analysis); LIHC cis rs4888262 0.508 rs4888258 chr16:74634198 G/T cg01733217 chr16:74700730 RFWD3 0.84 16.17 0.66 4.19e-44 Testicular germ cell tumor; LIHC cis rs7772486 0.754 rs6915718 chr6:146100676 A/G cg05347473 chr6:146136440 FBXO30 -0.37 -5.71 -0.3 2.43e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs11039798 0.582 rs60764175 chr11:48775856 T/G cg03929089 chr4:120376271 NA 0.53 6.13 0.31 2.36e-9 Axial length; LIHC cis rs950776 0.518 rs12910978 chr15:78810017 A/G cg22563815 chr15:78856949 CHRNA5 0.35 6.26 0.32 1.13e-9 Sudden cardiac arrest; LIHC cis rs12995491 0.569 rs6724281 chr2:88529531 T/G cg14558114 chr2:88469736 THNSL2 -0.71 -9.72 -0.47 6.89e-20 Response to metformin (IC50); LIHC cis rs753778 0.570 rs6578154 chr8:142210057 G/A cg18755752 chr8:142205143 DENND3 -0.31 -5.75 -0.3 1.98e-8 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01381637 chr19:50902842 POLD1 0.4 6.39 0.33 5.57e-10 Pancreatic cancer; LIHC cis rs9814567 1.000 rs4955555 chr3:134286427 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2380220 0.872 rs4546494 chr6:95990626 A/C cg04719120 chr6:96025338 MANEA 0.63 6.86 0.35 3.24e-11 Behavioural disinhibition (generation interaction); LIHC cis rs5769765 0.819 rs9616377 chr22:50310880 T/C cg26441486 chr22:50317300 CRELD2 0.36 5.73 0.3 2.16e-8 Schizophrenia; LIHC cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg00475322 chr7:917719 C7orf20 0.47 8.23 0.41 3.97e-15 Perceived unattractiveness to mosquitoes; LIHC cis rs3853824 0.898 rs6503767 chr17:54900047 C/T cg13675837 chr17:54910204 DGKE 0.42 5.93 0.31 7.59e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7953249 0.514 rs1169312 chr12:121441461 G/T cg02403541 chr12:121454288 C12orf43 0.47 8.33 0.41 2.02e-15 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs7223966 0.921 rs2854207 chr17:61947107 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.45 0.33 3.82e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7208859 0.623 rs7212991 chr17:29143749 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2303759 0.918 rs1054770 chr19:49878115 G/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.58 9.06 0.44 1.03e-17 Multiple sclerosis; LIHC trans rs2727020 0.796 rs7131672 chr11:49274421 A/C cg03929089 chr4:120376271 NA 0.67 9.47 0.46 4.65e-19 Coronary artery disease; LIHC cis rs9902453 0.817 rs62068625 chr17:28176581 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.32 0.55 4.05e-29 Coffee consumption (cups per day); LIHC cis rs7044106 0.762 rs4837789 chr9:123426256 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 8.1 0.4 1.01e-14 Hip circumference adjusted for BMI; LIHC trans rs1814175 0.817 rs4084376 chr11:49831160 T/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.53 -0.79 1.77e-73 Height; LIHC cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg20887711 chr4:1340912 KIAA1530 0.45 6.02 0.31 4.48e-9 Obesity-related traits; LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg09367891 chr1:107599246 PRMT6 -0.72 -11.91 -0.54 1.32e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6088590 0.542 rs6059956 chr20:33220070 A/G cg08999081 chr20:33150536 PIGU 0.69 14.07 0.61 8.35e-36 Coronary artery disease; LIHC trans rs2243480 1.000 rs3885839 chr7:65290403 G/T cg10756647 chr7:56101905 PSPH 1.11 13.27 0.58 1.06e-32 Diabetic kidney disease; LIHC cis rs6089829 0.851 rs6122346 chr20:61661822 C/G cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs1552244 0.572 rs17032440 chr3:10169819 A/C cg00149659 chr3:10157352 C3orf10 -0.88 -8.45 -0.42 8.25e-16 Alzheimer's disease; LIHC cis rs4555082 0.789 rs2816649 chr14:105708326 A/G cg06808227 chr14:105710500 BRF1 -0.62 -8.92 -0.43 2.8e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.53 0.56 6.56e-30 Prudent dietary pattern; LIHC cis rs6879260 1.000 rs7706951 chr5:179733407 C/T cg13944838 chr5:179740914 GFPT2 -0.51 -7.13 -0.36 5.86e-12 Height; LIHC cis rs1461503 0.966 rs1461501 chr11:122844416 A/G cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs3096299 0.748 rs3102339 chr16:89442711 C/T cg02187348 chr16:89574699 SPG7 0.44 6.43 0.33 4.2e-10 Multiple myeloma (IgH translocation); LIHC cis rs909002 0.830 rs10914461 chr1:32113217 G/A cg13919466 chr1:32135498 COL16A1 -0.37 -6.9 -0.35 2.48e-11 Intelligence (multi-trait analysis); LIHC cis rs1816752 0.870 rs3825449 chr13:25014441 A/C cg02811702 chr13:24901961 NA 0.26 6.64 0.34 1.25e-10 Obesity-related traits; LIHC cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg07061783 chr6:25882402 NA -0.46 -6.38 -0.33 5.67e-10 Blood metabolite levels; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.23 0.55 8.54e-29 Prudent dietary pattern; LIHC cis rs6582630 0.555 rs11181657 chr12:38381858 T/C cg26384229 chr12:38710491 ALG10B -0.57 -8.09 -0.4 1.06e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs11931598 0.702 rs10937780 chr4:7048842 A/G cg02503808 chr4:7069936 GRPEL1 -0.43 -6.69 -0.34 9.3e-11 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC trans rs208520 0.802 rs4710315 chr6:66887594 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.14 -0.4 7.28e-15 Exhaled nitric oxide output; LIHC cis rs875971 0.862 rs10240949 chr7:65804417 A/G cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs208520 0.874 rs208512 chr6:66943869 C/G cg07460842 chr6:66804631 NA -0.76 -8.28 -0.41 2.81e-15 Exhaled nitric oxide output; LIHC cis rs12701220 0.655 rs7784403 chr7:1153077 G/A cg26240231 chr7:1148101 C7orf50 -0.39 -5.85 -0.3 1.18e-8 Bronchopulmonary dysplasia; LIHC cis rs3736594 0.513 rs1881396 chr2:27844601 G/T cg27432699 chr2:27873401 GPN1 -0.46 -6.82 -0.35 4.17e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2637266 1.000 rs10219107 chr10:78364369 T/C cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.17e-8 Pulmonary function; LIHC cis rs10911363 0.615 rs9286848 chr1:183426249 C/G cg09173681 chr1:183549694 NCF2 -0.54 -9.51 -0.46 3.55e-19 Systemic lupus erythematosus; LIHC cis rs6500602 0.702 rs6500605 chr16:4502410 C/T cg08645402 chr16:4508243 NA 0.46 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg20102877 chr2:27665638 KRTCAP3 -0.44 -6.09 -0.31 3.02e-9 Total body bone mineral density; LIHC cis rs3806843 0.657 rs2563283 chr5:140105978 C/A cg26395211 chr5:140044315 WDR55 0.41 5.92 0.31 7.66e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs12478296 1.000 rs55777943 chr2:243040686 T/C cg18898632 chr2:242989856 NA -0.7 -8.76 -0.43 9.26e-17 Obesity-related traits; LIHC cis rs7666738 0.830 rs28878289 chr4:98855181 C/T cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07737236 chr3:161089327 C3orf57 0.49 7.0 0.35 1.35e-11 Lung function (FEV1/FVC); LIHC cis rs7772486 0.790 rs9390365 chr6:146235626 A/G cg05347473 chr6:146136440 FBXO30 -0.39 -6.1 -0.31 2.92e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1005277 0.579 rs2474588 chr10:38420870 A/G cg27523141 chr10:43048294 ZNF37B 0.37 6.47 0.33 3.32e-10 Extrinsic epigenetic age acceleration; LIHC cis rs55883249 0.957 rs16867083 chr2:9767441 C/T cg23886495 chr2:9695866 ADAM17 -0.72 -6.89 -0.35 2.63e-11 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; LIHC cis rs1865721 1.000 rs8091890 chr18:73197242 T/C cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.16e-13 Intelligence; LIHC cis rs10751667 1.000 rs7394449 chr11:962190 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.4 0.52 9.72e-26 Alzheimer's disease (late onset); LIHC cis rs6684514 1.000 rs12139321 chr1:156230429 A/G cg16558208 chr1:156270281 VHLL 0.51 9.28 0.45 2.02e-18 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs2073300 0.609 rs17757228 chr20:23351288 A/T cg12062639 chr20:23401060 NAPB 1.08 14.49 0.62 1.89e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7845219 0.525 rs7820818 chr8:95919231 G/A cg16049864 chr8:95962084 TP53INP1 -0.45 -6.58 -0.34 1.72e-10 Type 2 diabetes; LIHC cis rs2286503 0.839 rs1054471 chr7:22852643 T/A cg11367502 chr7:22862612 TOMM7 0.43 7.16 0.36 4.96e-12 Fibrinogen; LIHC cis rs1215050 0.791 rs984940 chr4:98811756 T/A cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.9e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6988636 1.000 rs4377946 chr8:124185887 T/C cg15893493 chr8:124194847 FAM83A 0.89 8.3 0.41 2.48e-15 Urinary uromodulin levels; LIHC trans rs61931739 0.500 rs11053222 chr12:34481100 C/A cg26384229 chr12:38710491 ALG10B 0.8 9.89 0.47 1.85e-20 Morning vs. evening chronotype; LIHC cis rs3749237 0.537 rs4459909 chr3:49469217 T/C cg06212747 chr3:49208901 KLHDC8B 0.44 5.85 0.3 1.13e-8 Resting heart rate; LIHC cis rs4555082 0.957 rs2735818 chr14:105714751 A/G cg06808227 chr14:105710500 BRF1 -0.63 -8.7 -0.43 1.44e-16 Mean platelet volume;Platelet distribution width; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg09324706 chr12:114395457 RBM19 0.42 6.42 0.33 4.68e-10 Alopecia areata; LIHC trans rs7618501 1.000 rs7374277 chr3:49784777 T/C cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.63 -0.34 1.3100000000000001e-10 Intelligence (multi-trait analysis); LIHC cis rs9914988 0.887 rs11080072 chr17:27081160 G/T cg20469991 chr17:27169893 C17orf63 -0.49 -6.04 -0.31 4.07e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg12292205 chr6:26970375 C6orf41 -0.41 -7.05 -0.36 9.67e-12 Schizophrenia; LIHC cis rs7260329 0.507 rs71358958 chr19:41530883 G/A cg10403441 chr19:41533888 NA 0.49 6.45 0.33 3.74e-10 Smoking behavior; LIHC cis rs10744422 1.000 rs7972447 chr12:123354545 C/G cg18912006 chr12:123335444 HIP1R -0.59 -6.79 -0.34 5.03e-11 Schizophrenia; LIHC cis rs3099143 1.000 rs3102709 chr15:77072260 C/T cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Recalcitrant atopic dermatitis; LIHC cis rs7771547 0.573 rs629721 chr6:36398229 T/C cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Platelet distribution width; LIHC cis rs6121246 0.567 rs6087700 chr20:30217560 A/G cg13852791 chr20:30311386 BCL2L1 0.78 6.77 0.34 5.69e-11 Mean corpuscular hemoglobin; LIHC cis rs7582720 1.000 rs114899426 chr2:203771652 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs1005277 0.502 rs2800484 chr10:38542415 C/T cg17830980 chr10:43048298 ZNF37B -0.49 -9.44 -0.45 5.8e-19 Extrinsic epigenetic age acceleration; LIHC cis rs10256972 0.684 rs2363279 chr7:1096143 A/G cg22907277 chr7:1156413 C7orf50 0.43 6.15 0.32 2.12e-9 Longevity;Endometriosis; LIHC cis rs17685 0.632 rs1859793 chr7:75821283 G/A cg16684958 chr7:75615977 POR 0.37 6.02 0.31 4.59e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10193935 1.000 rs13411405 chr2:42413811 C/A cg27598129 chr2:42591480 NA -0.73 -11.01 -0.51 2.42e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs1577917 0.958 rs12208227 chr6:86670944 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.82 -0.35 4.19e-11 Response to antipsychotic treatment; LIHC cis rs9911578 1.000 rs9904879 chr17:56864422 G/A cg12560992 chr17:57184187 TRIM37 0.97 17.46 0.69 2.94e-49 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.666 rs7396473 chr11:966181 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg16049864 chr8:95962084 TP53INP1 0.53 9.49 0.46 3.96e-19 Type 2 diabetes; LIHC cis rs7223966 1.000 rs113134232 chr17:61715461 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 7.17 0.36 4.68e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2380220 1.000 rs9632496 chr6:95976450 C/G cg04719120 chr6:96025338 MANEA 0.58 6.21 0.32 1.51e-9 Behavioural disinhibition (generation interaction); LIHC cis rs77861329 1.000 rs352147 chr3:52208285 A/G cg08692210 chr3:52188851 WDR51A 0.84 8.06 0.4 1.26e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs72627509 0.767 rs6853156 chr4:57774843 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.54 -7.93 -0.39 3.24e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs921968 0.541 rs523305 chr2:219402691 T/C cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs2727020 0.521 rs10839285 chr11:49496852 T/G cg15704280 chr7:45808275 SEPT13 0.8 12.51 0.56 7.98e-30 Coronary artery disease; LIHC cis rs965469 1.000 rs6051838 chr20:3389012 A/C cg25506879 chr20:3388711 C20orf194 -0.59 -6.75 -0.34 6.46e-11 IFN-related cytopenia; LIHC cis rs2842992 0.915 rs2758350 chr6:160118056 A/G cg26839252 chr6:160211577 TCP1;MRPL18 0.36 6.13 0.31 2.47e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs6089584 0.888 rs6061982 chr20:60620673 C/T cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01818597 chr11:63741913 COX8A 0.46 7.27 0.37 2.4e-12 Cognitive function; LIHC cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.16 0.32 2.01e-9 Menopause (age at onset); LIHC trans rs208520 0.837 rs208498 chr6:66931560 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.11 -0.4 9.46e-15 Exhaled nitric oxide output; LIHC cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.0 0.31 4.99e-9 Menopause (age at onset); LIHC cis rs2933343 0.951 rs789218 chr3:128592670 G/A cg25356066 chr3:128598488 ACAD9 0.54 6.99 0.35 1.49e-11 IgG glycosylation; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg18294483 chr11:96123194 JRKL;CCDC82 -0.43 -6.09 -0.31 3.05e-9 Eotaxin levels; LIHC cis rs2180341 1.000 rs7453272 chr6:127633959 C/T cg27446573 chr6:127587934 RNF146 -0.98 -14.73 -0.62 2.31e-38 Breast cancer; LIHC cis rs1008375 1.000 rs4698199 chr4:17656738 G/C cg16339924 chr4:17578868 LAP3 0.45 6.33 0.32 7.87e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1865760 0.516 rs9379819 chr6:26049819 A/C cg17691542 chr6:26056736 HIST1H1C 0.44 6.28 0.32 1.04e-9 Height; LIHC trans rs1814175 0.817 rs3974439 chr11:50022607 G/A cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs11696845 0.626 rs4810439 chr20:43377870 C/G cg25301532 chr20:43378953 KCNK15 -0.25 -5.87 -0.3 1.02e-8 Obesity-related traits; LIHC cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg00149659 chr3:10157352 C3orf10 0.7 7.1 0.36 7.09e-12 Alzheimer's disease; LIHC cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg11301795 chr4:187892539 NA 0.27 7.09 0.36 7.89e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.875 rs9376975 chr6:146355581 T/G cg05347473 chr6:146136440 FBXO30 0.37 5.95 0.31 6.49e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098699 0.821 rs6830451 chr4:124230386 G/A cg09941581 chr4:124220074 SPATA5 0.33 6.59 0.34 1.68e-10 Mosquito bite size; LIHC cis rs6570726 0.935 rs414646 chr6:145831685 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg17971929 chr21:40555470 PSMG1 0.51 7.77 0.39 9.55e-14 Cognitive function; LIHC cis rs9790314 0.934 rs9290074 chr3:160997823 T/C cg03342759 chr3:160939853 NMD3 -0.74 -9.13 -0.44 6.06e-18 Morning vs. evening chronotype; LIHC cis rs244293 0.730 rs12165058 chr17:53022049 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.03 -0.31 4.32e-9 Menarche (age at onset); LIHC cis rs1707322 0.721 rs12049027 chr1:46118184 A/T cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs950776 0.518 rs12900783 chr15:78815523 G/A cg22563815 chr15:78856949 CHRNA5 0.35 6.4 0.33 5.07e-10 Sudden cardiac arrest; LIHC cis rs2279817 0.731 rs78474704 chr1:18010154 T/C cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.76 -0.39 9.68e-14 Neuroticism; LIHC cis rs1843834 0.505 rs940317 chr2:225358118 C/T cg22509189 chr2:225307070 NA -0.83 -11.72 -0.54 6.47e-27 IgE levels in asthmatics (D.p. specific); LIHC cis rs7546 0.504 rs2075637 chr16:4938280 T/C cg08329684 chr16:4932620 PPL -0.42 -7.35 -0.37 1.43e-12 Cancer; LIHC cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs68170813 0.559 rs75007274 chr7:106814543 G/A cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs6456156 0.586 rs12528323 chr6:167461645 A/G cg07741184 chr6:167504864 NA 0.29 6.75 0.34 6.23e-11 Primary biliary cholangitis; LIHC cis rs875971 1.000 rs9986696 chr7:65704576 C/A cg11764359 chr7:65958608 NA -0.88 -15.37 -0.64 6.43e-41 Aortic root size; LIHC cis rs11098499 0.954 rs10006525 chr4:120408931 T/G cg09307838 chr4:120376055 NA 0.77 12.48 0.56 1.07e-29 Corneal astigmatism; LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg06601766 chr17:61851465 DDX42;CCDC47 0.58 8.86 0.43 4.47e-17 Height; LIHC cis rs870825 0.929 rs1405939 chr4:185591444 C/T cg04058563 chr4:185651563 MLF1IP 0.65 5.97 0.31 6.04e-9 Blood protein levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19049344 chr2:166095825 SCN2A -0.34 -6.74 -0.34 6.82e-11 Cognitive function; LIHC cis rs12477438 0.765 rs7571390 chr2:99626593 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.69 -10.17 -0.48 2.04e-21 Chronic sinus infection; LIHC cis rs1712517 0.744 rs4293063 chr10:105052976 G/T cg05636881 chr10:105038444 INA 0.46 7.01 0.35 1.31e-11 Migraine; LIHC cis rs10876993 0.893 rs3825078 chr12:58089413 A/T cg04478727 chr12:58166393 METTL1;FAM119B -0.42 -5.78 -0.3 1.64e-8 Celiac disease or Rheumatoid arthritis; LIHC cis rs35306767 0.909 rs12264390 chr10:959111 T/C cg20503657 chr10:835505 NA 0.9 10.72 0.5 2.52e-23 Eosinophil percentage of granulocytes; LIHC cis rs4843747 0.519 rs12599755 chr16:88107006 A/G cg06050784 chr16:88016603 BANP 0.38 6.94 0.35 1.93e-11 Menopause (age at onset); LIHC cis rs7107174 0.901 rs1055248 chr11:77925573 T/C cg02023728 chr11:77925099 USP35 0.54 10.46 0.49 2.08e-22 Testicular germ cell tumor; LIHC cis rs67311347 0.955 rs9821036 chr3:40379007 A/G cg13409248 chr3:40428643 ENTPD3 0.4 6.45 0.33 3.88e-10 Renal cell carcinoma; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.97 -0.31 5.99e-9 Total body bone mineral density; LIHC cis rs8084351 0.577 rs4578737 chr18:50664300 C/T cg24270629 chr18:50823537 DCC -0.44 -6.49 -0.33 3.1e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs367615 0.506 rs2963013 chr5:108775811 C/T cg17395555 chr5:108820864 NA -0.3 -6.48 -0.33 3.28e-10 Colorectal cancer (SNP x SNP interaction); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23868672 chr14:35344258 BAZ1A 0.42 6.37 0.33 5.96e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 1.000 rs422780 chr6:167406209 A/G cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.04e-24 Crohn's disease; LIHC cis rs4665809 1.000 rs6729080 chr2:26301282 G/A cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.02e-15 Gut microbiome composition (summer); LIHC cis rs11608355 0.515 rs3742018 chr12:109949134 C/T cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs12744310 1.000 rs56409354 chr1:41772971 G/A cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2834188 0.538 rs2026253 chr21:34687966 A/T cg14352951 chr21:34696688 IFNAR1 0.45 6.38 0.33 5.76e-10 Narcolepsy; LIHC trans rs11671005 0.504 rs2305119 chr19:59067623 C/T cg22037779 chr5:139682734 PFDN1 -0.52 -6.16 -0.32 2.07e-9 Mean platelet volume; LIHC cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg09904177 chr6:26538194 HMGN4 -0.55 -11.31 -0.52 2.06e-25 Intelligence (multi-trait analysis); LIHC cis rs7129220 0.588 rs61878581 chr11:10083808 C/T cg01453529 chr11:10209919 SBF2 -0.4 -7.04 -0.36 1.04e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs7818688 0.697 rs77055525 chr8:95980583 G/A cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4474465 1.000 rs1567889 chr11:78147055 A/G cg02023728 chr11:77925099 USP35 0.35 6.14 0.32 2.26e-9 Alzheimer's disease (survival time); LIHC cis rs6733011 0.508 rs925887 chr2:99514671 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.42 6.13 0.31 2.48e-9 Bipolar disorder; LIHC cis rs3767633 0.925 rs4657103 chr1:161740483 G/T cg09175582 chr1:161736000 ATF6 0.58 5.82 0.3 1.34e-8 IgG glycosylation; LIHC cis rs7119038 0.818 rs10892280 chr11:118611817 C/T cg19308663 chr11:118741387 NA 0.43 5.81 0.3 1.4e-8 Sjögren's syndrome; LIHC cis rs2228479 0.850 rs2238531 chr16:89856217 C/G cg19635926 chr16:89946313 TCF25 0.54 6.74 0.34 6.74e-11 Skin colour saturation; LIHC cis rs2066819 1.000 rs2306694 chr12:56680636 C/T cg26734620 chr12:56694298 CS -1.23 -11.01 -0.51 2.5300000000000002e-24 Psoriasis vulgaris; LIHC cis rs7927771 0.864 rs3781627 chr11:47441472 T/A cg20135002 chr11:47629003 NA 0.54 8.62 0.42 2.55e-16 Subjective well-being; LIHC cis rs11792861 0.589 rs75742991 chr9:111929624 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.55 6.9 0.35 2.55e-11 Menarche (age at onset); LIHC cis rs365132 0.934 rs149307 chr5:176471591 C/T cg16309518 chr5:176445507 NA -0.57 -10.94 -0.51 4.24e-24 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs929354 0.742 rs11980541 chr7:156988776 G/C cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs6430585 0.583 rs1435577 chr2:136624947 C/G cg15123519 chr2:136567270 LCT -0.37 -5.97 -0.31 5.9e-9 Corneal structure; LIHC cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.84 -0.54 2.51e-27 Alzheimer's disease; LIHC cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg06481639 chr22:41940642 POLR3H 0.61 5.87 0.3 1.02e-8 Vitiligo; LIHC trans rs8073060 0.586 rs3859284 chr17:34012792 C/T cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs8192917 1.000 rs10909625 chr14:25101629 A/G cg03875678 chr14:25103546 GZMB 0.43 7.63 0.38 2.34e-13 Vitiligo; LIHC cis rs1385374 0.858 rs10847692 chr12:129289679 A/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.7 0.38 1.46e-13 Systemic lupus erythematosus; LIHC cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs1335633 chr6:8448800 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs7187994 0.848 rs7498187 chr16:84770570 G/A cg07647771 chr16:84786436 USP10 -0.34 -6.17 -0.32 1.9e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs11628318 0.660 rs12887323 chr14:103083322 T/C cg23461800 chr14:103021989 NA -0.42 -5.87 -0.3 1.03e-8 Platelet count; LIHC cis rs637571 0.607 rs589253 chr11:65693080 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.4 0.41 1.25e-15 Eosinophil percentage of white cells; LIHC cis rs1707322 1.000 rs785506 chr1:46540652 C/T cg03146154 chr1:46216737 IPP -0.44 -7.05 -0.36 9.75e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6967414 0.786 rs7804259 chr7:6755448 C/G cg00387323 chr7:6746715 ZNF12 0.67 7.31 0.37 1.88e-12 Hematocrit;Hemoglobin concentration; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg02990361 chr1:107599529 PRMT6 0.58 9.71 0.46 7.79e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9470366 0.545 rs6930083 chr6:36634156 A/G cg08179530 chr6:36648295 CDKN1A -0.58 -8.73 -0.43 1.13e-16 QRS duration; LIHC cis rs4713118 0.513 rs149954 chr6:28035246 G/A cg16479474 chr6:28041457 NA 0.39 6.39 0.33 5.56e-10 Parkinson's disease; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.56 -7.77 -0.39 9.34e-14 Lymphocyte counts; LIHC cis rs4423214 0.879 rs4945008 chr11:71221248 A/G cg24826892 chr11:71159390 DHCR7 0.53 6.76 0.34 6.09e-11 Vitamin D levels; LIHC cis rs1799949 0.931 rs34474989 chr17:41445410 A/T cg05368731 chr17:41323189 NBR1 0.68 11.26 0.52 3.26e-25 Menopause (age at onset); LIHC cis rs847851 0.617 rs73403805 chr6:34964724 C/T cg13137465 chr6:34857473 ANKS1A 0.67 7.39 0.37 1.12e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs9341808 0.739 rs4706831 chr6:81007699 T/C cg08355045 chr6:80787529 NA 0.33 6.86 0.35 3.23e-11 Sitting height ratio; LIHC cis rs7927771 1.000 rs12363232 chr11:47623890 C/T cg20307385 chr11:47447363 PSMC3 -0.44 -5.81 -0.3 1.43e-8 Subjective well-being; LIHC cis rs36051895 0.587 rs16922785 chr9:5200409 C/G cg02405213 chr9:5042618 JAK2 -0.62 -9.7 -0.46 8.32e-20 Pediatric autoimmune diseases; LIHC cis rs965469 1.000 rs6051713 chr20:3265779 C/T cg25506879 chr20:3388711 C20orf194 0.57 6.96 0.35 1.79e-11 IFN-related cytopenia; LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs7584330 0.737 rs60187585 chr2:238365159 C/T cg14458575 chr2:238380390 NA 0.37 5.71 0.3 2.44e-8 Prostate cancer; LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03076246 chr16:67906784 EDC4 0.4 6.23 0.32 1.37e-9 Pancreatic cancer; LIHC cis rs611744 0.550 rs57045491 chr8:109279120 A/C cg18478394 chr8:109455254 TTC35 0.44 7.67 0.38 1.76e-13 Dupuytren's disease; LIHC cis rs2075371 0.897 rs12667905 chr7:134000812 A/C cg11752832 chr7:134001865 SLC35B4 0.48 6.08 0.31 3.3e-9 Mean platelet volume; LIHC cis rs3796352 1.000 rs11718834 chr3:52963668 A/C cg04865290 chr3:52927548 TMEM110 -0.49 -5.73 -0.3 2.22e-8 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2070488 0.804 rs13092473 chr3:38458958 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.28 0.55 5.77e-29 Electrocardiographic conduction measures; LIHC cis rs7618501 0.633 rs9853222 chr3:50022926 T/C cg24110177 chr3:50126178 RBM5 -0.48 -7.73 -0.39 1.21e-13 Intelligence (multi-trait analysis); LIHC cis rs17376456 0.825 rs10057130 chr5:93282557 C/T cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs4925386 1.000 rs6121990 chr20:60919263 G/A cg06026331 chr20:60912101 LAMA5 -0.51 -8.63 -0.42 2.36e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2971970 0.519 rs2346270 chr7:133647033 G/A cg03336402 chr7:133662267 EXOC4 -0.46 -5.74 -0.3 2.06e-8 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01534608 chr4:187646364 FAT1 0.48 6.82 0.35 4.18e-11 Pancreatic cancer; LIHC cis rs7615952 0.688 rs4422259 chr3:125545831 C/T cg05084668 chr3:125655381 ALG1L -0.34 -6.27 -0.32 1.11e-9 Blood pressure (smoking interaction); LIHC cis rs9303401 0.614 rs12948536 chr17:56580413 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.92 12.6 0.56 3.78e-30 Cognitive test performance; LIHC trans rs78049276 0.512 rs7659823 chr4:148398877 C/G cg13149281 chr14:23389818 RBM23;PRMT5 -0.68 -10.74 -0.5 2.29e-23 Pulse pressure; LIHC cis rs1707322 1.000 rs946524 chr1:46487560 A/G cg03146154 chr1:46216737 IPP -0.48 -7.88 -0.39 4.28e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs875971 0.929 rs10950041 chr7:65973875 T/C cg10756647 chr7:56101905 PSPH 0.44 6.46 0.33 3.62e-10 Aortic root size; LIHC cis rs765787 0.556 rs2413778 chr15:45539397 C/A cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg18306943 chr3:40428807 ENTPD3 0.42 7.37 0.37 1.3e-12 Renal cell carcinoma; LIHC cis rs12479064 0.671 rs62155807 chr2:100076579 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -6.93 -0.35 2.13e-11 Chronic sinus infection; LIHC cis rs1005277 0.579 rs2505240 chr10:38442419 G/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.58 -0.5 8.01e-23 Extrinsic epigenetic age acceleration; LIHC cis rs7131987 0.903 rs11050162 chr12:29420054 T/G cg16970926 chr12:29381810 FAR2 0.29 5.97 0.31 5.96e-9 QT interval; LIHC cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg18252515 chr7:66147081 NA -1.26 -17.06 -0.68 1.18e-47 Diabetic kidney disease; LIHC cis rs6973256 0.605 rs7792396 chr7:133345526 T/C cg10665199 chr7:133106180 EXOC4 0.34 5.86 0.3 1.1e-8 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs1498312 chr1:76177849 C/T cg22875332 chr1:76189707 ACADM 0.49 7.16 0.36 4.89e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9322817 0.691 rs2486141 chr6:105299930 G/A cg02098413 chr6:105308735 HACE1 0.43 8.14 0.4 7.25e-15 Thyroid stimulating hormone; LIHC cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg07061783 chr6:25882402 NA -0.47 -6.48 -0.33 3.29e-10 Blood metabolite levels; LIHC cis rs7927771 0.864 rs3781625 chr11:47443080 T/C cg20135002 chr11:47629003 NA -0.56 -9.59 -0.46 1.98e-19 Subjective well-being; LIHC cis rs60871478 0.945 rs62432254 chr7:804175 C/T cg05535760 chr7:792225 HEATR2 0.79 11.27 0.52 2.85e-25 Cerebrospinal P-tau181p levels; LIHC cis rs10193935 1.000 rs10173107 chr2:42420302 A/T cg27598129 chr2:42591480 NA -0.75 -11.47 -0.53 5.38e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs17401966 0.894 rs11587309 chr1:10446596 G/T cg19773385 chr1:10388646 KIF1B -0.38 -6.45 -0.33 3.76e-10 Hepatocellular carcinoma; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.4 0.33 5e-10 Renal cell carcinoma; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg19318889 chr4:1322082 MAEA 0.66 10.44 0.49 2.55e-22 Longevity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03705947 chr1:68152081 GADD45A 0.4 7.1 0.36 7.47e-12 Cognitive function; LIHC cis rs2425143 1.000 rs28685274 chr20:34358527 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.53 -6.89 -0.35 2.64e-11 Blood protein levels; LIHC cis rs10744422 0.920 rs897393 chr12:123312051 A/G cg18912006 chr12:123335444 HIP1R 0.56 6.77 0.34 5.6e-11 Schizophrenia; LIHC cis rs7613875 0.600 rs1138536 chr3:50153356 C/T cg05623727 chr3:50126028 RBM5 0.34 6.07 0.31 3.39e-9 Body mass index; LIHC cis rs2204008 0.775 rs8186812 chr12:38305055 C/T cg26384229 chr12:38710491 ALG10B 0.57 7.83 0.39 6.31e-14 Bladder cancer; LIHC cis rs2153535 0.542 rs6905925 chr6:8440030 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs644799 0.687 rs11021318 chr11:95522996 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.25 0.58 1.27e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs787274 0.543 rs4978509 chr9:115635641 C/G cg13803584 chr9:115635662 SNX30 -0.59 -8.46 -0.42 8.05e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs829883 0.664 rs865509 chr12:98854444 T/A cg25150519 chr12:98850993 NA 0.7 11.21 0.52 4.79e-25 Colorectal adenoma (advanced); LIHC cis rs2933343 0.951 rs1055128 chr3:128591048 C/T cg25356066 chr3:128598488 ACAD9 0.55 7.36 0.37 1.4e-12 IgG glycosylation; LIHC trans rs208520 0.690 rs864314 chr6:66814830 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.05 -20.79 -0.75 1.17e-62 Exhaled nitric oxide output; LIHC cis rs13118159 0.836 rs2276903 chr4:1343405 A/G cg19318889 chr4:1322082 MAEA 0.38 5.87 0.3 1.01e-8 Longevity; LIHC cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1707322 0.752 rs8179296 chr1:46143791 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.77 0.39 9.04e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3762637 1.000 rs9836309 chr3:122135195 G/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs8058578 1.000 rs2289442 chr16:30739919 A/G cg02466173 chr16:30829666 NA -0.46 -7.57 -0.38 3.41e-13 Multiple myeloma; LIHC cis rs727505 1.000 rs67084428 chr7:124499388 G/T cg23710748 chr7:124431027 NA -0.32 -5.78 -0.3 1.66e-8 Lewy body disease; LIHC cis rs12477438 0.700 rs12467679 chr2:99654449 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.93 -0.65 4.13e-43 Chronic sinus infection; LIHC cis rs10870270 1.000 rs9971066 chr10:133788233 G/A cg17892150 chr10:133769511 PPP2R2D -0.67 -12.32 -0.55 3.99e-29 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6882046 0.513 rs587490 chr5:88032522 C/T cg22951263 chr5:87985283 NA -0.39 -6.81 -0.35 4.53e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs919433 0.679 rs10497806 chr2:198508951 G/A cg03934865 chr2:198174659 NA 0.47 7.06 0.36 9.38e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2932538 0.961 rs12126494 chr1:113228623 G/A cg22162597 chr1:113214053 CAPZA1 0.71 9.25 0.45 2.54e-18 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs9733 0.596 rs7538493 chr1:150655421 T/C cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Tonsillectomy; LIHC cis rs61677309 0.964 rs55815657 chr11:118155074 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01635816 chr20:2082448 STK35 0.45 6.18 0.32 1.81e-9 Pancreatic cancer; LIHC cis rs2243480 0.901 rs778732 chr7:65822360 C/T cg18252515 chr7:66147081 NA -1.29 -17.35 -0.68 8.27e-49 Diabetic kidney disease; LIHC cis rs17666538 0.535 rs1669658 chr8:607380 A/G cg23958373 chr8:599963 NA 0.82 6.21 0.32 1.58e-9 IgG glycosylation; LIHC cis rs3806843 0.648 rs2530233 chr5:140082876 A/G cg26395211 chr5:140044315 WDR55 0.4 5.87 0.3 1.01e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs600806 0.854 rs3768496 chr1:109866569 T/A cg16275483 chr1:110013120 SYPL2 -0.49 -6.11 -0.31 2.76e-9 Intelligence (multi-trait analysis); LIHC cis rs6912958 1.000 rs2207144 chr6:88150816 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.4 -7.04 -0.36 1.04e-11 Monocyte percentage of white cells; LIHC cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg25204440 chr1:209979598 IRF6 0.52 8.0 0.4 1.91e-14 Cleft lip with or without cleft palate; LIHC cis rs4853012 0.838 rs59570457 chr2:74344282 T/C cg20891558 chr2:74357851 NA 0.82 17.05 0.68 1.3e-47 Gestational age at birth (maternal effect); LIHC cis rs6964587 1.000 rs416 chr7:91580571 A/G cg17063962 chr7:91808500 NA -1.01 -19.24 -0.72 1.97e-56 Breast cancer; LIHC trans rs60843830 1.000 rs55753056 chr2:243929 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.52 0.46 3.32e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs7223966 1.000 rs112143304 chr17:61822401 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.65 7.39 0.37 1.14e-12 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09745873 chr9:130653159 ST6GALNAC6 0.4 6.47 0.33 3.35e-10 Cognitive function; LIHC cis rs10464366 0.560 rs11763728 chr7:39145862 C/T cg18850127 chr7:39170497 POU6F2 0.4 7.58 0.38 3.35e-13 IgG glycosylation; LIHC cis rs8062405 0.755 rs62034355 chr16:28581038 G/C cg07451762 chr16:28383216 NA 0.4 6.99 0.35 1.42e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2425143 1.000 rs6058311 chr20:34321895 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs16877106 0.661 rs16877005 chr4:25313994 A/G cg04796973 chr4:25314218 ZCCHC4 0.54 5.8 0.3 1.54e-8 Weight; LIHC cis rs514406 0.760 rs475969 chr1:53292607 T/A cg08859206 chr1:53392774 SCP2 -0.39 -6.31 -0.32 8.72e-10 Monocyte count; LIHC cis rs10751667 0.600 rs7394783 chr11:1005108 C/T cg06064525 chr11:970664 AP2A2 0.43 10.36 0.49 4.87e-22 Alzheimer's disease (late onset); LIHC cis rs8062405 1.000 rs62037364 chr16:28868695 G/A cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10454142 0.666 rs11678403 chr2:48550497 G/A cg15846641 chr2:48541264 FOXN2 0.49 5.75 0.3 1.97e-8 Sex hormone-binding globulin levels; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg07677032 chr17:61819896 STRADA 0.41 6.05 0.31 3.91e-9 Prudent dietary pattern; LIHC cis rs76419734 0.510 rs28391170 chr4:106629246 A/C cg24545054 chr4:106630052 GSTCD;INTS12 0.77 8.77 0.43 8.36e-17 Post bronchodilator FEV1; LIHC cis rs1873147 0.569 rs8029221 chr15:63308583 C/T cg12160578 chr15:63334699 TPM1 0.68 8.88 0.43 3.8e-17 Orofacial clefts; LIHC cis rs739401 0.572 rs389128 chr11:3083873 G/T cg05729581 chr11:3078854 CARS -0.46 -6.32 -0.32 8.38e-10 Longevity; LIHC cis rs929354 0.772 rs933344 chr7:157011265 A/T cg05182265 chr7:156933206 UBE3C -0.33 -6.28 -0.32 1e-9 Body mass index; LIHC cis rs6459804 1.000 rs6459804 chr7:157510195 C/T cg05731713 chr7:157510257 PTPRN2 0.23 6.52 0.33 2.58e-10 Bipolar disorder and schizophrenia; LIHC cis rs11671005 0.735 rs34188294 chr19:58919557 G/A cg25952890 chr19:58913133 NA 0.66 6.81 0.35 4.31e-11 Mean platelet volume; LIHC cis rs4689592 0.503 rs4689064 chr4:7055603 A/G cg19539972 chr4:7069911 GRPEL1 -0.7 -9.9 -0.47 1.71e-20 Monocyte percentage of white cells; LIHC cis rs9612 1.000 rs1058 chr19:44268325 C/G cg08581076 chr19:44259116 C19orf61 0.61 7.49 0.38 6.11e-13 Exhaled nitric oxide output; LIHC trans rs4650994 0.544 rs4132058 chr1:178505557 A/C cg05059571 chr16:84539110 KIAA1609 -0.41 -7.06 -0.36 9.58e-12 HDL cholesterol levels;HDL cholesterol; LIHC trans rs1464321 0.951 rs7488867 chr12:103699685 C/T cg15403093 chr12:133312361 ANKLE2 0.39 6.14 0.32 2.26e-9 Body mass index; LIHC cis rs7917772 0.536 rs12357172 chr10:104388549 C/T cg22532475 chr10:104410764 TRIM8 -0.39 -6.37 -0.33 5.99e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs12142240 0.660 rs72885163 chr1:46807117 C/A cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs34779708 0.931 rs4934724 chr10:35393669 C/T cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7647973 0.710 rs7629322 chr3:49621994 C/T cg03060546 chr3:49711283 APEH 0.6 6.91 0.35 2.34e-11 Menarche (age at onset); LIHC cis rs826838 1.000 rs2129627 chr12:38653036 C/T cg13010199 chr12:38710504 ALG10B 0.64 7.58 0.38 3.2e-13 Heart rate; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17187048 chr2:122407283 CLASP1 0.51 8.0 0.4 2.01e-14 Cognitive function; LIHC cis rs903552 1.000 rs4965873 chr15:102004023 A/G cg00659931 chr15:102010125 PCSK6 0.46 6.35 0.32 6.91e-10 Diabetic kidney disease; LIHC cis rs4605213 0.686 rs8076111 chr17:49302782 C/G cg00965052 chr17:49230932 NME1;NME1-NME2 -0.45 -5.94 -0.31 6.91e-9 Height; LIHC cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg07061783 chr6:25882402 NA -0.47 -6.48 -0.33 3.29e-10 Blood metabolite levels; LIHC cis rs9902453 0.967 rs4356528 chr17:28489670 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.4 0.45 7.96e-19 Coffee consumption (cups per day); LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg09367891 chr1:107599246 PRMT6 0.65 9.93 0.47 1.34e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9517313 0.565 rs9556978 chr13:99234648 G/A cg20487152 chr13:99095054 FARP1 -0.4 -6.47 -0.33 3.41e-10 Neuroticism; LIHC cis rs10984561 0.588 rs1412055 chr9:122249965 G/A cg14242995 chr9:122249943 NA 0.38 6.03 0.31 4.3e-9 Pulmonary function decline; LIHC trans rs61931739 0.517 rs11053063 chr12:34181011 C/T cg26384229 chr12:38710491 ALG10B 0.6 7.67 0.38 1.83e-13 Morning vs. evening chronotype; LIHC cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg08499158 chr17:42289980 UBTF 0.52 8.51 0.42 5.47e-16 Total body bone mineral density; LIHC cis rs3741404 0.791 rs7102177 chr11:63909228 T/C cg24431193 chr11:63883947 FLRT1;MACROD1 -0.38 -5.9 -0.3 8.94e-9 Platelet count; LIHC cis rs11577318 0.853 rs2276712 chr1:26627478 T/C cg10402321 chr1:26617780 UBXN11 -0.38 -5.8 -0.3 1.48e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs8078723 0.546 rs8067817 chr17:38163936 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.64 -11.61 -0.53 1.76e-26 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2228479 0.681 rs10153055 chr16:89965842 C/T cg06558623 chr16:89946397 TCF25 0.81 11.12 0.52 1.02e-24 Skin colour saturation; LIHC cis rs295140 0.507 rs13019821 chr2:201106815 C/G cg23649088 chr2:200775458 C2orf69 -0.48 -6.65 -0.34 1.17e-10 QT interval; LIHC cis rs10949834 0.504 rs13238778 chr7:73567709 G/A cg07137043 chr7:73588983 EIF4H -0.71 -8.03 -0.4 1.59e-14 Verbal memory performance (residualized delayed recall change); LIHC cis rs9457247 0.534 rs9356551 chr6:167400345 T/C cg23791538 chr6:167370224 RNASET2 0.75 13.88 0.6 4.5e-35 Crohn's disease; LIHC cis rs11671005 0.616 rs12980907 chr19:58956326 C/T cg25952890 chr19:58913133 NA 0.71 7.75 0.39 1.09e-13 Mean platelet volume; LIHC cis rs7412746 0.658 rs4970988 chr1:150950062 A/G cg18016565 chr1:150552671 MCL1 -0.49 -9.32 -0.45 1.51e-18 Melanoma; LIHC cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg17554472 chr22:41940697 POLR3H 0.54 5.8 0.3 1.48e-8 Vitiligo; LIHC trans rs1005277 0.522 rs289647 chr10:37968278 A/G cg17830980 chr10:43048298 ZNF37B -0.39 -7.55 -0.38 3.9e-13 Extrinsic epigenetic age acceleration; LIHC cis rs7212590 0.655 rs16943969 chr17:58031153 A/G cg10252138 chr17:58120427 NA -0.58 -5.87 -0.3 1.01e-8 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs7843479 0.601 rs12056476 chr8:21854188 T/A cg17168535 chr8:21777572 XPO7 0.57 9.92 0.47 1.52e-20 Mean corpuscular volume; LIHC cis rs1062177 0.756 rs2964589 chr5:151118189 G/T cg00977110 chr5:151150581 G3BP1 -0.58 -7.22 -0.36 3.29e-12 Preschool internalizing problems; LIHC cis rs78456975 0.506 rs10167704 chr2:1571037 G/C cg01028140 chr2:1542097 TPO -0.35 -5.72 -0.3 2.37e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg13516796 chr16:5122251 ALG1 0.42 6.13 0.31 2.47e-9 Morning vs. evening chronotype; LIHC cis rs2836974 0.568 rs11910906 chr21:40685662 T/C cg06238570 chr21:40685208 BRWD1 -0.57 -9.53 -0.46 3e-19 Cognitive function; LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg09455208 chr3:40491958 NA 0.4 8.25 0.41 3.44e-15 Renal cell carcinoma; LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg11965913 chr1:205819406 PM20D1 0.63 9.24 0.45 2.71e-18 Menarche (age at onset); LIHC cis rs7615952 0.673 rs9841194 chr3:125635739 C/T cg05084668 chr3:125655381 ALG1L -0.81 -10.6 -0.5 6.61e-23 Blood pressure (smoking interaction); LIHC cis rs9911578 0.967 rs2643124 chr17:56741672 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.74 0.69 2.14e-50 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.520 rs2516835 chr2:99779131 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs3736485 0.934 rs17609924 chr15:51911592 G/A cg08986416 chr15:51914746 DMXL2 -0.47 -6.99 -0.35 1.49e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs72627509 0.638 rs78272732 chr4:57870537 T/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.63 -8.97 -0.44 2e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs780096 0.565 rs8179252 chr2:27746832 A/C cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.88e-10 Total body bone mineral density; LIHC cis rs9921222 0.521 rs11649255 chr16:357140 A/G cg00101154 chr16:420108 MRPL28 -0.52 -7.47 -0.37 6.67e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs796364 1.000 rs281788 chr2:200783705 A/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 8.99 0.44 1.71e-17 Schizophrenia; LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg07167872 chr1:205819463 PM20D1 0.59 8.75 0.43 1.01e-16 Menarche (age at onset); LIHC cis rs9649213 0.555 rs67132564 chr7:98014900 T/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.79 -0.3 1.56e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs6951245 0.580 rs77101766 chr7:1122438 A/G cg04025307 chr7:1156635 C7orf50 0.69 6.76 0.34 6.14e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6424115 1.000 rs7521961 chr1:24157634 C/T cg15997130 chr1:24165203 NA -0.45 -9.01 -0.44 1.51e-17 Immature fraction of reticulocytes; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg13492291 chr12:133312126 ANKLE2 0.36 6.54 0.33 2.24e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs798554 0.610 rs1182209 chr7:2808595 C/T cg13628971 chr7:2884303 GNA12 0.41 6.54 0.33 2.29e-10 Height; LIHC cis rs7107174 1.000 rs114142124 chr11:78047537 T/C cg02023728 chr11:77925099 USP35 0.45 8.4 0.41 1.18e-15 Testicular germ cell tumor; LIHC cis rs11628318 0.660 rs35258120 chr14:103058769 G/A cg12046867 chr14:103022105 NA -0.5 -7.2 -0.36 3.94e-12 Platelet count; LIHC cis rs12744310 0.887 rs35464028 chr1:41800474 T/G cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg05368731 chr17:41323189 NBR1 0.72 12.06 0.55 3.69e-28 Menopause (age at onset); LIHC cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg17372223 chr3:52568218 NT5DC2 0.35 5.83 0.3 1.28e-8 Bipolar disorder; LIHC cis rs3741404 0.609 rs651855 chr11:63870810 T/C cg18225595 chr11:63971243 STIP1 0.46 7.35 0.37 1.49e-12 Platelet count; LIHC cis rs17106184 0.892 rs12063007 chr1:51166302 G/T cg07174182 chr1:51127561 FAF1 -0.6 -6.77 -0.34 5.75e-11 Type 2 diabetes; LIHC cis rs7772486 0.686 rs4895684 chr6:146114023 A/C cg23711669 chr6:146136114 FBXO30 -0.64 -11.5 -0.53 4.35e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9816226 0.618 rs1516728 chr3:185829891 A/T cg00760338 chr3:185826511 ETV5 0.95 15.5 0.64 2.06e-41 Obesity;Body mass index; LIHC cis rs10716631 1 rs10716631 chr2:219138170 T/G cg20019365 chr2:219134978 PNKD;AAMP 0.79 12.66 0.56 2.23e-30 High light scatter reticulocyte percentage of red cells;Plateletcrit; LIHC cis rs6120849 0.754 rs3818253 chr20:33596876 C/T cg24642439 chr20:33292090 TP53INP2 0.66 7.38 0.37 1.21e-12 Protein C levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg16280946 chr22:20716554 NA 0.42 6.07 0.31 3.48e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs838721 0.574 rs13014016 chr2:234257454 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.41 5.85 0.3 1.12e-8 Total body bone mineral density; LIHC trans rs2727020 0.786 rs10839263 chr11:49354462 A/G cg18944383 chr4:111397179 ENPEP 0.28 6.55 0.33 2.14e-10 Coronary artery disease; LIHC cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.04 0.55 4.36e-28 Alzheimer's disease; LIHC cis rs208520 0.754 rs851594 chr6:66876695 A/G cg07460842 chr6:66804631 NA -0.79 -8.82 -0.43 5.87e-17 Exhaled nitric oxide output; LIHC cis rs7534824 0.543 rs61780317 chr1:101407139 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.86 0.39 5.2e-14 Refractive astigmatism; LIHC cis rs6840360 0.571 rs4696274 chr4:152528478 C/A cg22705602 chr4:152727874 NA -0.33 -6.27 -0.32 1.08e-9 Intelligence (multi-trait analysis); LIHC cis rs1559088 0.847 rs8110181 chr19:33605939 G/A cg27124370 chr19:33622961 WDR88 0.52 8.19 0.41 5.16e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2108225 0.872 rs6980029 chr7:107446127 T/C cg18560240 chr7:107437656 SLC26A3 -0.44 -6.78 -0.34 5.44e-11 Ulcerative colitis; LIHC cis rs35110281 0.805 rs2838319 chr21:44991901 A/G cg01579765 chr21:45077557 HSF2BP -0.34 -6.51 -0.33 2.73e-10 Mean corpuscular volume; LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.706 rs4795375 chr17:37662932 T/C cg07936489 chr17:37558343 FBXL20 -0.84 -12.09 -0.55 2.86e-28 Glomerular filtration rate (creatinine); LIHC cis rs959260 1.000 rs4789184 chr17:73383314 A/G cg20590849 chr17:73267439 MIF4GD -0.54 -5.8 -0.3 1.51e-8 Systemic lupus erythematosus; LIHC cis rs3762637 1.000 rs6777596 chr3:122133321 C/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.65 -0.46 1.19e-19 LDL cholesterol levels; LIHC cis rs7586673 1.000 rs7586673 chr2:161923520 C/A cg21518248 chr2:162101506 NA 0.39 5.81 0.3 1.4e-8 Intelligence (multi-trait analysis); LIHC cis rs477895 0.713 rs35095324 chr11:63948412 G/A cg04317338 chr11:64019027 PLCB3 0.85 10.22 0.48 1.41e-21 Mean platelet volume; LIHC cis rs12586317 0.547 rs10145723 chr14:35460954 G/A cg16230307 chr14:35515116 FAM177A1 0.78 13.14 0.58 3.26e-32 Psoriasis; LIHC cis rs7412746 0.552 rs4970980 chr1:150864992 A/C cg18016565 chr1:150552671 MCL1 0.49 9.4 0.45 8.09e-19 Melanoma; LIHC cis rs7131987 0.718 rs7976961 chr12:29463088 C/T cg12903224 chr12:29470962 FAR2 -0.42 -6.79 -0.34 4.9e-11 QT interval; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.43 -6.05 -0.31 3.77e-9 Longevity; LIHC cis rs765787 0.530 rs4775831 chr15:45534722 A/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs1577917 0.816 rs1838952 chr6:86601144 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.38 -7.01 -0.35 1.3e-11 Response to antipsychotic treatment; LIHC cis rs6466055 0.777 rs2299319 chr7:104877916 C/T cg04380332 chr7:105027541 SRPK2 -0.36 -6.74 -0.34 6.6e-11 Schizophrenia; LIHC cis rs11671005 0.656 rs73066226 chr19:59008213 T/C cg25952890 chr19:58913133 NA 0.67 6.44 0.33 4.15e-10 Mean platelet volume; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg00280220 chr17:61926910 NA 0.42 6.51 0.33 2.71e-10 Prudent dietary pattern; LIHC cis rs7107174 1.000 rs1318241 chr11:77930792 C/T cg02023728 chr11:77925099 USP35 0.51 9.49 0.46 3.99e-19 Testicular germ cell tumor; LIHC cis rs9467773 1.000 rs1078679 chr6:26568741 C/T cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.62e-34 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg24693881 chr1:107596107 NA -0.52 -9.16 -0.44 5e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.08e-11 Alzheimer's disease; LIHC cis rs10876993 0.821 rs1678522 chr12:58049923 G/A cg18357645 chr12:58087776 OS9 0.53 8.58 0.42 3.26e-16 Celiac disease or Rheumatoid arthritis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23685580 chr15:43940867 CATSPER2 -0.44 -6.4 -0.33 5.2400000000000005e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg06238570 chr21:40685208 BRWD1 -0.53 -8.77 -0.43 8.46e-17 Cognitive function; LIHC cis rs7520050 0.743 rs61789988 chr1:46085242 G/C cg03146154 chr1:46216737 IPP -0.48 -8.1 -0.4 9.55e-15 Red blood cell count;Reticulocyte count; LIHC cis rs9309473 0.950 rs6546849 chr2:73831037 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.88 -0.35 2.9100000000000002e-11 Metabolite levels; LIHC cis rs11098699 0.821 rs6811839 chr4:124222326 G/A cg09941581 chr4:124220074 SPATA5 0.34 6.79 0.34 4.84e-11 Mosquito bite size; LIHC cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg21724239 chr8:58056113 NA 0.58 7.23 0.36 3.14e-12 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.866 rs13125526 chr4:120288019 G/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs7487075 0.619 rs10785627 chr12:46824229 G/A cg23829395 chr12:46796953 NA 0.35 6.17 0.32 1.97e-9 Itch intensity from mosquito bite; LIHC cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs317689 0.718 rs315122 chr12:69771073 G/T cg19645103 chr12:69753606 YEATS4 -0.46 -6.28 -0.32 1e-9 Response to diuretic therapy; LIHC cis rs344364 0.511 rs56077812 chr16:1948870 T/G cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.99 -0.4 2.13e-14 Lymphocyte counts; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg05002041 chr16:23652837 DCTN5;PALB2 -0.34 -6.3 -0.32 9.18e-10 Bilirubin levels; LIHC cis rs60871478 1.000 rs4374882 chr7:821798 C/T cg27478167 chr7:817139 HEATR2 -0.41 -5.89 -0.3 9.18e-9 Cerebrospinal P-tau181p levels; LIHC cis rs7264396 0.690 rs2425175 chr20:34445563 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.83 -0.51 1.07e-23 Total cholesterol levels; LIHC cis rs1707322 1.000 rs785498 chr1:46592414 C/T cg03146154 chr1:46216737 IPP -0.47 -7.64 -0.38 2.16e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6545883 0.895 rs2421192 chr2:61643631 T/C cg15711740 chr2:61764176 XPO1 0.43 6.09 0.31 3.11e-9 Tuberculosis; LIHC cis rs6977660 1.000 rs5017193 chr7:19820103 G/A cg07541023 chr7:19748670 TWISTNB 0.36 5.74 0.3 2.1e-8 Thyroid stimulating hormone; LIHC cis rs4713118 0.513 rs149989 chr6:27998184 T/A cg23485639 chr6:28045615 ZNF165 0.39 5.94 0.31 7.13e-9 Parkinson's disease; LIHC cis rs3770081 1.000 rs6718632 chr2:86176084 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.39 5.79 0.3 1.64e-8 Facial emotion recognition (sad faces); LIHC cis rs875971 0.638 rs6960778 chr7:66071597 C/T cg11764359 chr7:65958608 NA -0.72 -10.77 -0.5 1.73e-23 Aortic root size; LIHC cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 2.97e-30 Menopause (age at onset); LIHC cis rs9911578 0.839 rs7208505 chr17:57187729 C/T cg05425664 chr17:57184151 TRIM37 -0.52 -7.64 -0.38 2.19e-13 Intelligence (multi-trait analysis); LIHC cis rs240764 0.658 rs12212435 chr6:101196080 T/C cg09795085 chr6:101329169 ASCC3 -0.45 -6.68 -0.34 9.69e-11 Neuroticism; LIHC cis rs6831352 0.673 rs1154403 chr4:100009590 C/T cg12011299 chr4:100065546 ADH4 0.49 7.88 0.39 4.54e-14 Alcohol dependence; LIHC cis rs6001982 0.541 rs5995890 chr22:41051302 G/C cg14879645 chr22:41048474 NA 0.4 5.8 0.3 1.53e-8 Breast cancer; LIHC cis rs2439831 0.850 rs2439832 chr15:43779686 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.64 8.93 0.43 2.72e-17 Lung cancer in ever smokers; LIHC cis rs9658691 0.607 rs12416581 chr10:90780440 C/T cg03111039 chr10:90751583 FAS;ACTA2 -0.76 -5.98 -0.31 5.47e-9 Mosquito bite size; LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg06497051 chr1:156261200 TMEM79 0.38 6.05 0.31 3.83e-9 Tonsillectomy; LIHC trans rs10915437 0.536 rs6663939 chr1:4197256 C/T cg23269655 chr10:75541687 CHCHD1 0.4 6.04 0.31 4.06e-9 Migraine - clinic-based; LIHC cis rs796364 0.774 rs112564437 chr2:201074048 G/C cg23649088 chr2:200775458 C2orf69 -0.43 -5.78 -0.3 1.7e-8 Schizophrenia; LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg01411255 chr17:61851458 DDX42;CCDC47 0.95 19.27 0.72 1.55e-56 Height; LIHC cis rs1538970 0.884 rs781232 chr1:45890399 C/T cg15605315 chr1:45957053 TESK2 0.44 5.95 0.31 6.59e-9 Platelet count; LIHC cis rs362296 0.698 rs3095083 chr4:3263499 G/A cg06533319 chr4:3265114 C4orf44 0.34 6.35 0.32 6.9e-10 Parental longevity (mother's age at death); LIHC cis rs3008870 0.959 rs2985816 chr1:67387750 G/T cg02640540 chr1:67518911 SLC35D1 0.42 5.78 0.3 1.64e-8 Lymphocyte percentage of white cells; LIHC cis rs7107174 0.901 rs7110387 chr11:78117875 A/G cg02023728 chr11:77925099 USP35 0.4 7.13 0.36 6.19e-12 Testicular germ cell tumor; LIHC cis rs12220238 1.000 rs11000925 chr10:75972601 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.54 0.33 2.25e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2072499 0.750 rs55910626 chr1:156159909 C/G cg24450063 chr1:156163899 SLC25A44 0.76 8.07 0.4 1.19e-14 Testicular germ cell tumor; LIHC cis rs782590 0.783 rs7594279 chr2:55812073 T/G cg03859395 chr2:55845619 SMEK2 0.85 15.05 0.63 1.22e-39 Metabolic syndrome; LIHC cis rs7772486 0.875 rs1331640 chr6:146427250 G/A cg05347473 chr6:146136440 FBXO30 0.37 5.78 0.3 1.64e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs17683430 0.614 rs2006253 chr22:32530256 A/C cg19942213 chr7:117476040 CTTNBP2 0.69 6.11 0.31 2.67e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC trans rs916888 0.773 rs199448 chr17:44809001 A/G cg16836995 chr17:43662488 NA -0.77 -7.92 -0.39 3.28e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2153535 0.563 rs6942177 chr6:8534460 A/G cg07606381 chr6:8435919 SLC35B3 -0.8 -11.81 -0.54 3.2e-27 Motion sickness; LIHC cis rs2404602 0.735 rs2957614 chr15:76696635 C/T cg23625390 chr15:77176239 SCAPER 0.46 7.68 0.38 1.65e-13 Blood metabolite levels; LIHC cis rs6499255 0.951 rs74026882 chr16:69635059 A/G cg15192750 chr16:69999425 NA 0.45 6.86 0.35 3.22e-11 IgE levels; LIHC cis rs11671005 0.651 rs10402325 chr19:58913507 A/G cg25952890 chr19:58913133 NA 0.69 7.08 0.36 8.04e-12 Mean platelet volume; LIHC cis rs7520050 1.000 rs785511 chr1:46534498 T/C cg03146154 chr1:46216737 IPP -0.36 -6.01 -0.31 4.78e-9 Red blood cell count;Reticulocyte count; LIHC trans rs2832191 0.740 rs13048618 chr21:30458684 A/G cg14791747 chr16:20752902 THUMPD1 -0.45 -6.32 -0.32 8.19e-10 Dental caries; LIHC cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg00825309 chr19:58991885 ZNF446 -0.53 -8.36 -0.41 1.64e-15 Uric acid clearance; LIHC cis rs8014204 0.604 rs11625594 chr14:75389833 G/A cg08847533 chr14:75593920 NEK9 0.45 7.38 0.37 1.2e-12 Caffeine consumption; LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg20570016 chr1:156261298 TMEM79 0.38 6.08 0.31 3.22e-9 Tonsillectomy; LIHC trans rs875971 0.545 rs3735147 chr7:65970528 A/C cg26939375 chr7:64535504 NA 0.42 6.63 0.34 1.32e-10 Aortic root size; LIHC cis rs6952808 0.771 rs10275045 chr7:1920826 C/T cg04267008 chr7:1944627 MAD1L1 -0.65 -10.34 -0.49 5.5e-22 Bipolar disorder and schizophrenia; LIHC cis rs929354 0.742 rs62491945 chr7:156955580 G/A cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs13064411 0.627 rs9872168 chr3:113233132 A/C cg18753928 chr3:113234510 CCDC52 -0.43 -6.08 -0.31 3.14e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 8.87e-33 Prudent dietary pattern; LIHC cis rs10870270 0.956 rs10870281 chr10:133762642 G/A cg08754478 chr10:133766260 PPP2R2D -0.54 -8.03 -0.4 1.58e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9640161 0.830 rs17173682 chr7:150059602 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.52 -0.42 5.34e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs17095355 1.000 rs12242642 chr10:111724213 G/A cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.84 -0.3 1.21e-8 Biliary atresia; LIHC cis rs2235642 0.621 rs2667665 chr16:1569524 A/C cg09065629 chr16:1709722 CRAMP1L 0.33 5.75 0.3 1.98e-8 Coronary artery disease; LIHC cis rs9611519 0.780 rs9611542 chr22:41677317 C/T cg06481639 chr22:41940642 POLR3H -0.53 -5.84 -0.3 1.19e-8 Neuroticism; LIHC cis rs67311347 1.000 rs7617989 chr3:40512463 A/G cg09455208 chr3:40491958 NA -0.36 -7.23 -0.36 3.18e-12 Renal cell carcinoma; LIHC cis rs12579753 0.956 rs35278765 chr12:82173126 T/C cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg13616963 chr3:57583610 ARF4 -0.41 -6.43 -0.33 4.29e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs365132 0.846 rs812246 chr5:176327644 G/A cg16309518 chr5:176445507 NA -0.51 -9.69 -0.46 8.59e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs9649465 0.967 rs2286831 chr7:123303477 A/G cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.59e-14 Migraine; LIHC cis rs7917772 0.636 rs2250580 chr10:104505687 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.48 5.86 0.3 1.11e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.68 0.34 9.67e-11 Bipolar disorder; LIHC cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg03517284 chr6:25882590 NA -0.63 -8.86 -0.43 4.45e-17 Blood metabolite levels; LIHC cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg02187348 chr16:89574699 SPG7 0.62 10.08 0.48 4.18e-21 Multiple myeloma (IgH translocation); LIHC cis rs10857712 0.950 rs11101744 chr10:135226041 G/C cg01444801 chr10:135216882 MTG1 -0.67 -10.36 -0.49 4.7e-22 Systemic lupus erythematosus; LIHC cis rs7903847 0.619 rs76094900 chr10:99158164 G/A cg08345082 chr10:99160200 RRP12 -0.39 -6.41 -0.33 4.72e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs8017423 0.935 rs12884698 chr14:90750566 G/A cg04374321 chr14:90722782 PSMC1 -0.77 -14.66 -0.62 4.39e-38 Mortality in heart failure; LIHC cis rs8060686 0.516 rs8062085 chr16:68289313 C/A cg05110241 chr16:68378359 PRMT7 -0.54 -6.51 -0.33 2.67e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs2842992 0.830 rs2273819 chr6:160183325 G/C cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.56 0.42 3.83e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs9303401 0.614 rs2333409 chr17:57139134 G/A cg25039879 chr17:56429692 SUPT4H1 0.76 8.79 0.43 7.19e-17 Cognitive test performance; LIHC cis rs6445975 0.715 rs4681835 chr3:58263351 T/G cg23715586 chr3:58305044 RPP14 -0.37 -6.21 -0.32 1.52e-9 Systemic lupus erythematosus; LIHC cis rs9916302 0.904 rs801426 chr17:37441109 C/T cg07936489 chr17:37558343 FBXL20 0.84 13.74 0.6 1.59e-34 Glomerular filtration rate (creatinine); LIHC cis rs12579753 1.000 rs11115015 chr12:82174543 T/C cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC cis rs10504229 0.610 rs6993531 chr8:58147283 A/G cg20607798 chr8:58055168 NA 0.51 6.37 0.33 5.93e-10 Developmental language disorder (linguistic errors); LIHC cis rs769267 0.930 rs2304098 chr19:19646272 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.6 0.38 2.91e-13 Tonsillectomy; LIHC cis rs7927771 0.864 rs112060627 chr11:47426956 G/A cg20135002 chr11:47629003 NA -0.58 -10.01 -0.48 7.32e-21 Subjective well-being; LIHC cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg04287289 chr16:89883240 FANCA 0.55 9.26 0.45 2.26e-18 Vitiligo; LIHC cis rs7582720 1.000 rs72934512 chr2:203926271 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9486715 0.867 rs9486181 chr6:96868132 G/A cg06623918 chr6:96969491 KIAA0776 0.86 14.87 0.63 6.41e-39 Headache; LIHC cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg11890956 chr21:40555474 PSMG1 -0.49 -8.26 -0.41 3.32e-15 Menarche (age at onset); LIHC cis rs9443189 0.570 rs9341532 chr6:76403674 A/G cg01950844 chr6:76311363 SENP6 0.87 10.9 0.51 6.08e-24 Prostate cancer; LIHC cis rs4407350 0.870 rs5765714 chr22:44915203 T/C cg26276947 chr22:44892394 LDOC1L 0.34 6.39 0.33 5.35e-10 Intelligence (multi-trait analysis); LIHC cis rs11871801 0.846 rs4792923 chr17:40690118 G/C cg14558262 chr17:40713999 COASY -0.51 -6.97 -0.35 1.6e-11 Crohn's disease; LIHC trans rs792448 0.743 rs351373 chr1:212426631 G/T cg20223728 chr6:6006398 NRN1 0.34 6.2 0.32 1.66e-9 White blood cell count (basophil); LIHC cis rs3096299 0.900 rs4785663 chr16:89434888 G/A cg06640241 chr16:89574553 SPG7 0.62 9.83 0.47 3.01e-20 Multiple myeloma (IgH translocation); LIHC cis rs17253792 0.822 rs10151664 chr14:56029533 A/G cg01858014 chr14:56050164 KTN1 -0.65 -7.18 -0.36 4.5e-12 Putamen volume; LIHC cis rs5758511 0.680 rs56111723 chr22:42664883 T/A cg00645731 chr22:42541494 CYP2D7P1 0.53 8.37 0.41 1.48e-15 Birth weight; LIHC cis rs1707322 0.662 rs11211160 chr1:46146229 T/A cg06784218 chr1:46089804 CCDC17 0.39 7.32 0.37 1.74e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs62244186 0.627 rs12386385 chr3:44457540 A/G cg25364880 chr3:44379878 C3orf23 0.72 10.45 0.49 2.36e-22 Depressive symptoms; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21144940 chr19:1993265 BTBD2 0.44 6.46 0.33 3.51e-10 Cognitive function; LIHC cis rs4790333 0.531 rs2447107 chr17:2257864 A/G cg02569219 chr17:2266849 SGSM2 0.42 6.35 0.32 6.92e-10 Proinsulin levels; LIHC cis rs2832191 0.671 rs73346699 chr21:30515529 C/T cg24692254 chr21:30365293 RNF160 -0.44 -6.77 -0.34 5.63e-11 Dental caries; LIHC cis rs1198430 0.636 rs2811963 chr1:23824242 A/C cg13183780 chr1:23809682 ASAP3 -0.59 -8.09 -0.4 1.04e-14 Total cholesterol levels; LIHC trans rs9375946 0.512 rs12191555 chr6:99537716 A/G cg01500633 chr6:86387148 SNORD50A;SNHG5 -0.45 -6.22 -0.32 1.46e-9 Depressive symptoms; LIHC cis rs17376456 1.000 rs34013242 chr5:93507947 C/T cg25358565 chr5:93447407 FAM172A 1.08 9.83 0.47 3.04e-20 Diabetic retinopathy; LIHC trans rs12478296 1.000 rs113129906 chr2:243004253 C/T cg01596870 chr19:55963115 NA -0.62 -7.33 -0.37 1.68e-12 Obesity-related traits; LIHC trans rs1493916 0.777 rs1493910 chr18:31318376 A/G cg27147174 chr7:100797783 AP1S1 -0.49 -6.86 -0.35 3.31e-11 Life satisfaction; LIHC cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.73 0.39 1.2e-13 Electroencephalogram traits; LIHC cis rs12474201 0.925 rs17822294 chr2:46960004 G/A cg06386533 chr2:46925753 SOCS5 0.77 8.7 0.43 1.45e-16 Height; LIHC cis rs6701037 0.748 rs11585368 chr1:175135448 G/A cg17845761 chr1:175162550 KIAA0040 -0.42 -6.84 -0.35 3.61e-11 Alcohol dependence; LIHC cis rs7613875 0.537 rs6446195 chr3:50070853 A/G cg05623727 chr3:50126028 RBM5 -0.34 -5.89 -0.3 9.31e-9 Body mass index; LIHC cis rs9467773 1.000 rs6903973 chr6:26499942 C/A cg09904177 chr6:26538194 HMGN4 0.66 13.79 0.6 1.01e-34 Intelligence (multi-trait analysis); LIHC cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.04 -10.69 -0.5 3.39e-23 Platelet count; LIHC cis rs317689 0.690 rs570256 chr12:69662929 A/T cg20891283 chr12:69753455 YEATS4 0.51 7.41 0.37 9.72e-13 Response to diuretic therapy; LIHC cis rs2404602 0.692 rs67010831 chr15:76965308 T/G cg03037974 chr15:76606532 NA 0.74 14.52 0.62 1.54e-37 Blood metabolite levels; LIHC cis rs11711311 1.000 rs13070720 chr3:113473754 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.44 8.47 0.42 7.11e-16 IgG glycosylation; LIHC cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg13699009 chr12:122356056 WDR66 0.49 8.32 0.41 2.18e-15 Mean corpuscular volume; LIHC cis rs2576037 0.526 rs642897 chr18:44396917 T/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.56 0.5 9.41e-23 Personality dimensions; LIHC cis rs875971 0.862 rs3893216 chr7:65790707 G/C cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs7615952 0.599 rs2279821 chr3:125734308 G/A cg05084668 chr3:125655381 ALG1L -0.42 -6.66 -0.34 1.13e-10 Blood pressure (smoking interaction); LIHC cis rs858239 0.669 rs6461687 chr7:23116580 A/G cg23682824 chr7:23144976 KLHL7 0.43 6.31 0.32 8.83e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs12464559 0.826 rs10196143 chr2:152599229 C/T cg01189475 chr2:152685088 ARL5A 0.65 6.56 0.33 2.05e-10 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs8017423 0.626 rs8003363 chr14:90826840 T/C cg04374321 chr14:90722782 PSMC1 -0.49 -7.1 -0.36 7.09e-12 Mortality in heart failure; LIHC cis rs3748682 0.821 rs71642605 chr1:38256427 T/C cg12658694 chr1:38397304 INPP5B 0.45 6.11 0.31 2.75e-9 Hypothyroidism; LIHC cis rs600806 0.778 rs4970731 chr1:109995459 T/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -5.9 -0.3 8.91e-9 Intelligence (multi-trait analysis); LIHC cis rs7639513 0.590 rs3729931 chr3:12626516 A/G cg23032965 chr3:12705835 RAF1 -0.57 -7.5 -0.38 5.57e-13 Itch intensity from mosquito bite; LIHC cis rs60871478 0.645 rs111968669 chr7:856683 C/T cg04727924 chr7:799746 HEATR2 0.53 6.76 0.34 5.98e-11 Cerebrospinal P-tau181p levels; LIHC cis rs7107174 0.901 rs2450137 chr11:77925233 C/G cg02023728 chr11:77925099 USP35 0.54 10.53 0.49 1.24e-22 Testicular germ cell tumor; LIHC cis rs225245 0.817 rs225290 chr17:33927904 C/G cg05299278 chr17:33885742 SLFN14 0.22 6.0 0.31 5.1e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15640707 chr5:89705759 CETN3 0.4 6.24 0.32 1.29e-9 Calcium levels; LIHC cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg03517284 chr6:25882590 NA -0.64 -9.06 -0.44 9.93e-18 Blood metabolite levels; LIHC cis rs2066819 0.786 rs111580405 chr12:56739557 A/G cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs11690935 0.959 rs1113389 chr2:172635365 C/T cg13550731 chr2:172543902 DYNC1I2 -0.94 -18.94 -0.72 3.09e-55 Schizophrenia; LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg08682334 chr16:737214 WDR24 -0.44 -6.27 -0.32 1.11e-9 Gut microbiome composition (summer); LIHC cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg11644478 chr21:40555479 PSMG1 -0.39 -6.2 -0.32 1.66e-9 Menarche (age at onset); LIHC cis rs5762813 0.566 rs4055 chr22:29352495 A/C cg15103426 chr22:29168792 CCDC117 0.44 6.09 0.31 2.96e-9 Hematocrit;Hemoglobin concentration; LIHC cis rs17253792 0.731 rs8008528 chr14:56062052 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC trans rs1814175 0.817 rs7947286 chr11:49874657 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.35 -0.78 8.99e-73 Height; LIHC cis rs6089584 1.000 rs6089581 chr20:60562394 G/A cg12751644 chr20:60527061 NA -0.37 -6.09 -0.31 3.12e-9 Body mass index; LIHC cis rs6684514 0.922 rs12047994 chr1:156284535 C/A cg16558208 chr1:156270281 VHLL 0.55 10.36 0.49 4.85e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs372883 0.648 rs1153288 chr21:30686091 A/G cg24692254 chr21:30365293 RNF160 0.47 5.93 0.31 7.4e-9 Pancreatic cancer; LIHC cis rs8014204 0.816 rs28426374 chr14:75346740 C/T cg08847533 chr14:75593920 NEK9 -0.36 -5.99 -0.31 5.23e-9 Caffeine consumption; LIHC cis rs1866706 1.000 rs10734205 chr11:12861267 C/T cg25843174 chr11:12811716 TEAD1 -0.31 -6.56 -0.33 1.94e-10 Intelligence (multi-trait analysis); LIHC cis rs1816752 0.905 rs1050112 chr13:25009297 G/T cg22771759 chr13:24902376 NA 0.33 6.79 0.34 4.98e-11 Obesity-related traits; LIHC cis rs9596863 0.898 rs9568902 chr13:54324954 G/A ch.13.53330881F chr13:54432880 NA 0.44 6.08 0.31 3.2e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs55665837 1.000 rs10832276 chr11:14483274 C/T cg19336497 chr11:14380999 RRAS2 -0.45 -8.22 -0.41 4.23e-15 Vitamin D levels; LIHC cis rs5758511 0.633 rs5758690 chr22:42668295 C/G cg00645731 chr22:42541494 CYP2D7P1 0.52 8.29 0.41 2.59e-15 Birth weight; LIHC cis rs735396 0.770 rs1169314 chr12:121443116 A/G cg02403541 chr12:121454288 C12orf43 0.52 9.16 0.44 4.88e-18 N-glycan levels; LIHC cis rs7618501 0.966 rs2352974 chr3:49890613 C/T cg21467203 chr3:49911342 NA -0.38 -6.48 -0.33 3.18e-10 Intelligence (multi-trait analysis); LIHC cis rs909341 0.716 rs71325463 chr20:62362834 G/A cg03999872 chr20:62272968 STMN3 -0.46 -6.81 -0.35 4.41e-11 Atopic dermatitis; LIHC cis rs1003719 0.667 rs2835606 chr21:38490851 G/C cg10648535 chr21:38446584 PIGP;TTC3 0.56 6.52 0.33 2.51e-10 Eye color traits; LIHC cis rs8177179 0.505 rs1405023 chr3:133481128 T/C cg24879335 chr3:133465180 TF -0.33 -6.81 -0.35 4.47e-11 Iron status biomarkers (transferrin levels); LIHC cis rs7572733 0.534 rs700674 chr2:198693703 C/T cg00792783 chr2:198669748 PLCL1 0.46 6.82 0.35 4.1e-11 Dermatomyositis; LIHC cis rs875971 0.862 rs11984115 chr7:65773859 C/T cg11764359 chr7:65958608 NA -0.78 -13.42 -0.59 2.76e-33 Aortic root size; LIHC cis rs4268898 0.965 rs4665673 chr2:24459737 A/T cg06627628 chr2:24431161 ITSN2 0.52 7.4 0.37 1.05e-12 Asthma; LIHC cis rs881375 0.715 rs7858209 chr9:123645760 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.41 6.13 0.31 2.48e-9 Rheumatoid arthritis; LIHC cis rs2380220 0.541 rs72928273 chr6:96079360 C/T cg04719120 chr6:96025338 MANEA -0.69 -8.18 -0.4 5.63e-15 Behavioural disinhibition (generation interaction); LIHC trans rs4843747 0.671 rs72818540 chr16:88078988 C/T cg09572067 chr16:29127029 RRN3P2 0.54 8.21 0.41 4.55e-15 Menopause (age at onset); LIHC trans rs11722228 0.508 rs73212864 chr4:10104191 G/A cg26043149 chr18:55253948 FECH 0.98 13.75 0.6 1.46e-34 Gout;Urate levels;Serum uric acid levels; LIHC cis rs7715806 0.509 rs34349 chr5:74944868 A/G cg19683494 chr5:74908142 NA -0.88 -10.95 -0.51 4.08e-24 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg27297192 chr10:134578999 INPP5A 0.55 8.08 0.4 1.1e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6570726 0.846 rs409553 chr6:145886963 C/T cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.2e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6463523 0.933 rs4724821 chr7:762544 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 1.04 19.22 0.72 2.37e-56 Subjective well-being; LIHC cis rs10916814 0.632 rs4439331 chr1:20897091 T/C cg24502330 chr1:20914028 CDA -0.31 -6.82 -0.35 4.1e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9381040 0.655 rs2294696 chr6:41036988 A/G cg25110423 chr6:41068646 NFYA;LOC221442 0.38 6.25 0.32 1.22e-9 Alzheimer's disease (late onset); LIHC cis rs858239 0.600 rs10233039 chr7:23143113 G/A cg18081818 chr7:23246105 NA -0.38 -5.83 -0.3 1.3e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg05590025 chr7:65112418 INTS4L2 -0.51 -6.2 -0.32 1.59e-9 Diabetic kidney disease; LIHC cis rs3736485 0.934 rs11634999 chr15:51871461 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1.05e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2549003 0.966 rs2706386 chr5:131832687 C/T cg21138405 chr5:131827807 IRF1 -0.37 -9.77 -0.47 4.66e-20 Asthma (sex interaction); LIHC cis rs1055129 0.655 rs3744006 chr17:73838816 G/A cg19302996 chr17:73780495 UNK -0.59 -9.41 -0.45 7.44e-19 White matter hyperintensity burden; LIHC cis rs754466 0.580 rs1054608 chr10:79543308 T/G cg17075019 chr10:79541650 NA -0.79 -12.41 -0.56 1.83e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.8e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2997447 0.669 rs61776584 chr1:26438455 T/C cg19633962 chr1:26362018 EXTL1 -0.5 -5.75 -0.3 1.97e-8 QRS complex (12-leadsum); LIHC cis rs4820294 1.000 rs7291867 chr22:38062112 C/G cg00292662 chr22:38071168 LGALS1 0.63 9.97 0.47 1.03e-20 Fat distribution (HIV); LIHC cis rs13191362 0.935 rs73023493 chr6:162952769 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.73 5.99 0.31 5.45e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6918586 0.658 rs198843 chr6:26110314 A/T cg18357526 chr6:26021779 HIST1H4A -0.54 -7.91 -0.39 3.58e-14 Schizophrenia; LIHC cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg03806693 chr22:41940476 POLR3H 1.08 12.81 0.57 6.14e-31 Vitiligo; LIHC cis rs7572733 0.534 rs1436131 chr2:198731230 A/C cg10820045 chr2:198174542 NA 0.47 7.07 0.36 8.78e-12 Dermatomyositis; LIHC trans rs9926296 0.607 rs11076629 chr16:89875259 T/C cg13698153 chr12:118541722 VSIG10 0.58 6.26 0.32 1.12e-9 Vitiligo; LIHC cis rs55665837 0.540 rs10832299 chr11:14769392 G/A cg00085434 chr11:14927489 NA 0.4 5.77 0.3 1.78e-8 Vitamin D levels; LIHC cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg21486233 chr12:29375141 FAR2 0.3 5.85 0.3 1.14e-8 QT interval; LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg02782426 chr3:40428986 ENTPD3 -0.33 -6.24 -0.32 1.29e-9 Renal cell carcinoma; LIHC cis rs10883723 0.810 rs7094751 chr10:104274818 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC cis rs743757 1.000 rs762897 chr3:50428766 C/A cg05260129 chr3:50388622 TUSC4;CYB561D2 0.43 5.9 0.3 8.95e-9 Diastolic blood pressure; LIHC cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg23758822 chr17:41437982 NA 0.94 17.54 0.69 1.39e-49 Menopause (age at onset); LIHC cis rs8067354 0.645 rs2645492 chr17:57875554 A/G cg13753209 chr17:57696993 CLTC -0.76 -12.25 -0.55 7.28e-29 Hemoglobin concentration; LIHC cis rs4780401 0.609 rs11639945 chr16:11824056 T/G cg01061890 chr16:11836724 TXNDC11 -0.64 -10.2 -0.48 1.69e-21 Rheumatoid arthritis; LIHC cis rs6684514 1.000 rs12121805 chr1:156257876 A/G cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7267979 1.000 rs1046073 chr20:25281333 G/A cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC trans rs4596713 0.538 rs10869961 chr9:71787071 C/T cg16512924 chr15:28394682 HERC2 0.38 6.22 0.32 1.45e-9 Headache; LIHC cis rs9596863 0.950 rs9563182 chr13:54395310 T/C ch.13.53330881F chr13:54432880 NA 0.43 5.74 0.3 2.08e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9341808 0.700 rs12215236 chr6:80975058 A/T cg08355045 chr6:80787529 NA 0.35 7.34 0.37 1.55e-12 Sitting height ratio; LIHC trans rs2727020 0.617 rs1917311 chr11:49422665 C/T cg15704280 chr7:45808275 SEPT13 -0.97 -19.92 -0.73 3.7e-59 Coronary artery disease; LIHC trans rs4650994 1.000 rs35810840 chr1:178522642 G/A cg05059571 chr16:84539110 KIAA1609 -0.38 -6.4 -0.33 5.09e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs12586317 0.620 rs12588810 chr14:35554484 C/T cg05294307 chr14:35346193 BAZ1A -0.46 -6.72 -0.34 7.6e-11 Psoriasis; LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg06420487 chr17:61919686 SMARCD2 0.43 5.85 0.3 1.16e-8 Height; LIHC cis rs2797160 0.547 rs1418645 chr6:125946476 T/A cg05901451 chr6:126070800 HEY2 -0.45 -8.06 -0.4 1.25e-14 Endometrial cancer; LIHC cis rs3784262 1.000 rs4646593 chr15:58302467 A/G cg12031962 chr15:58353849 ALDH1A2 -0.35 -7.02 -0.35 1.22e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs10911232 0.507 rs10797820 chr1:183011366 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.01e-22 Hypertriglyceridemia; LIHC cis rs1983891 1.000 rs6458228 chr6:41543793 C/A cg20194872 chr6:41519635 FOXP4 0.4 6.33 0.32 7.78e-10 Prostate cancer; LIHC cis rs10870270 0.956 rs10430618 chr10:133748996 C/T cg08754478 chr10:133766260 PPP2R2D -0.53 -7.75 -0.39 1.07e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs34172651 0.517 rs36113933 chr16:24838862 A/G cg04756594 chr16:24857601 SLC5A11 0.61 9.02 0.44 1.33e-17 Intelligence (multi-trait analysis); LIHC cis rs4589502 0.528 rs8039656 chr15:67208848 G/A cg12317470 chr15:67143691 NA -0.45 -5.88 -0.3 9.79e-9 Lung cancer (smoking interaction); LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg06656553 chr16:89960601 TCF25 -0.49 -6.2 -0.32 1.6e-9 Skin colour saturation; LIHC cis rs12291225 0.546 rs12795545 chr11:14355564 G/A cg05501817 chr11:14380813 RRAS2 -0.45 -6.29 -0.32 9.56e-10 Sense of smell; LIHC cis rs7223966 0.921 rs2727300 chr17:61965398 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.52 6.22 0.32 1.46e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg08219700 chr8:58056026 NA 0.54 7.02 0.35 1.19e-11 Developmental language disorder (linguistic errors); LIHC cis rs4808199 0.895 rs2163805 chr19:19575945 G/A cg21559469 chr19:19431446 KIAA0892;SF4 0.42 5.73 0.3 2.21e-8 Nonalcoholic fatty liver disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02429622 chr10:30024742 SVIL -0.53 -6.16 -0.32 2.06e-9 Systolic blood pressure; LIHC cis rs1801251 1.000 rs13003675 chr2:233584109 C/T cg25237894 chr2:233734115 C2orf82 0.57 11.03 0.51 2.06e-24 Coronary artery disease; LIHC cis rs7587476 0.954 rs3768708 chr2:215645046 C/T cg04004882 chr2:215674386 BARD1 -0.49 -6.54 -0.33 2.19e-10 Neuroblastoma; LIHC cis rs7927592 0.956 rs7126340 chr11:68257293 C/T cg20283391 chr11:68216788 NA -0.5 -7.52 -0.38 4.86e-13 Total body bone mineral density; LIHC cis rs9486719 0.790 rs2499790 chr6:96845078 G/A cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg13409248 chr3:40428643 ENTPD3 -0.5 -8.49 -0.42 6.42e-16 Renal cell carcinoma; LIHC cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg07424592 chr7:64974309 NA 0.83 9.5 0.46 3.78e-19 Diabetic kidney disease; LIHC cis rs8072100 0.764 rs4794371 chr17:45627693 G/C cg08085267 chr17:45401833 C17orf57 0.39 5.91 0.3 8.48e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4819052 0.851 rs2236445 chr21:46678453 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.71 0.38 1.43e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1008375 1.000 rs6811887 chr4:17640858 C/T cg02297831 chr4:17616191 MED28 0.51 7.96 0.4 2.49e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17818399 0.533 rs4384837 chr2:46789514 A/G cg02822958 chr2:46747628 ATP6V1E2 0.43 6.81 0.35 4.42e-11 Height; LIHC cis rs1499614 1.000 rs1267817 chr7:66110040 G/T cg12463550 chr7:65579703 CRCP 0.67 6.86 0.35 3.16e-11 Gout; LIHC cis rs7116495 1.000 rs2511114 chr11:71792147 T/C cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs9818758 0.607 rs73084135 chr3:49272218 A/G cg00383909 chr3:49044727 WDR6 1.08 7.83 0.39 6.23e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs172166 0.694 rs536704 chr6:28092603 T/G cg25329415 chr6:28076851 NA 0.27 5.71 0.3 2.41e-8 Cardiac Troponin-T levels; LIHC cis rs7647973 0.626 rs62262722 chr3:49769419 G/C cg03060546 chr3:49711283 APEH -0.56 -6.12 -0.31 2.55e-9 Menarche (age at onset); LIHC cis rs6430585 0.528 rs309159 chr2:136684940 C/T cg25344623 chr2:136566232 LCT -0.34 -5.89 -0.3 9e-9 Corneal structure; LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg05185784 chr16:90016020 DEF8 -0.45 -5.84 -0.3 1.21e-8 Skin colour saturation; LIHC cis rs9513627 0.510 rs4365162 chr13:100212614 G/C cg25919922 chr13:100150906 NA 0.78 7.03 0.36 1.13e-11 Obesity-related traits; LIHC cis rs908922 0.676 rs7545336 chr1:152527863 A/G cg20991723 chr1:152506922 NA 0.53 8.88 0.43 3.78e-17 Hair morphology; LIHC cis rs12586317 0.547 rs2273154 chr14:35433187 C/T cg05294307 chr14:35346193 BAZ1A -0.49 -7.19 -0.36 4.12e-12 Psoriasis; LIHC cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg12153709 chr19:56196971 EPN1 0.42 6.04 0.31 4e-9 Bilirubin levels; LIHC cis rs9952991 0.941 rs9952749 chr18:12780456 A/G cg23598886 chr18:12777645 NA 0.48 6.48 0.33 3.27e-10 Inflammatory skin disease; LIHC cis rs34779708 0.931 rs7079205 chr10:35324619 C/T cg03585969 chr10:35415529 CREM 0.89 12.94 0.57 1.93e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2991971 0.967 rs7526665 chr1:46005832 G/T cg15605315 chr1:45957053 TESK2 0.45 6.14 0.32 2.3e-9 High light scatter reticulocyte count; LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 -1.0 -11.0 -0.51 2.63e-24 Platelet count; LIHC cis rs4820294 0.669 rs9622678 chr22:38057338 A/G cg00142150 chr22:38071001 LGALS1 0.44 7.53 0.38 4.5e-13 Fat distribution (HIV); LIHC cis rs2731664 0.792 rs2544809 chr5:176885499 T/C cg23176889 chr5:176863531 GRK6 -0.72 -12.63 -0.56 2.81e-30 Intelligence (multi-trait analysis); LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg13773083 chr2:220197274 RESP18 -0.38 -6.22 -0.32 1.44e-9 Lung cancer in ever smokers; LIHC cis rs2370759 1.000 rs79442609 chr10:32608749 C/T cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs9942416 0.533 rs12109685 chr5:75024066 A/G cg19683494 chr5:74908142 NA 0.58 6.25 0.32 1.2e-9 Age-related disease endophenotypes; LIHC cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.43 7.27 0.37 2.53e-12 Electroencephalogram traits; LIHC cis rs6500602 0.727 rs8051389 chr16:4570570 C/T cg08645402 chr16:4508243 NA 0.44 8.25 0.41 3.35e-15 Schizophrenia; LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.55 -0.33 2.16e-10 Menopause (age at onset); LIHC cis rs2303759 0.881 rs10412811 chr19:49884495 G/A cg24324837 chr19:49891574 CCDC155 0.39 6.14 0.32 2.29e-9 Multiple sclerosis; LIHC cis rs920590 0.758 rs7012358 chr8:19662498 C/T cg17834443 chr8:19674713 INTS10 0.48 7.02 0.35 1.2e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs1538970 0.962 rs9429076 chr1:45819489 A/G cg24296786 chr1:45957014 TESK2 -0.47 -6.79 -0.34 5.09e-11 Platelet count; LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg02990361 chr1:107599529 PRMT6 -0.67 -11.17 -0.52 6.58e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6942756 1.000 rs67820265 chr7:128887925 A/G cg02491457 chr7:128862824 NA -0.71 -11.09 -0.51 1.24e-24 White matter hyperintensity burden; LIHC cis rs11229555 0.874 rs11605269 chr11:58350872 A/G cg15696309 chr11:58395628 NA -0.71 -8.73 -0.43 1.11e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2576037 0.583 rs8098948 chr18:44512332 C/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.4 -5.73 -0.3 2.23e-8 Personality dimensions; LIHC cis rs3736485 0.934 rs4775955 chr15:51873449 C/T cg08986416 chr15:51914746 DMXL2 0.42 6.28 0.32 1.04e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2072499 0.966 rs2253677 chr1:156171296 C/G cg24450063 chr1:156163899 SLC25A44 -1.06 -19.15 -0.72 4.8e-56 Testicular germ cell tumor; LIHC cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.4 0.45 8.18e-19 Platelet count; LIHC cis rs12594515 1.000 rs11070464 chr15:45984776 C/A cg01629716 chr15:45996671 NA 0.52 9.48 0.46 4.49e-19 Waist circumference;Weight; LIHC cis rs6088580 0.505 rs6058106 chr20:33278255 T/C cg08999081 chr20:33150536 PIGU -0.42 -6.94 -0.35 1.98e-11 Glomerular filtration rate (creatinine); LIHC cis rs7542091 0.704 rs1883331 chr1:210043483 A/G cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs910316 1.000 rs175436 chr14:75608683 C/G cg08847533 chr14:75593920 NEK9 -0.85 -17.99 -0.7 2.14e-51 Height; LIHC cis rs2242116 0.900 rs4683300 chr3:46934292 C/A cg02527881 chr3:46936655 PTH1R -0.54 -11.92 -0.54 1.2e-27 Birth weight; LIHC cis rs80282103 0.867 rs7075830 chr10:1091650 G/C cg18964960 chr10:1102726 WDR37 0.72 6.63 0.34 1.32e-10 Glomerular filtration rate (creatinine); LIHC cis rs10463316 0.928 rs4958267 chr5:150752643 A/T cg03212797 chr5:150827313 SLC36A1 -0.45 -6.88 -0.35 2.89e-11 Metabolite levels (Pyroglutamine); LIHC cis rs240764 0.817 rs239229 chr6:101105975 T/C cg09795085 chr6:101329169 ASCC3 0.53 7.46 0.37 7.07e-13 Neuroticism; LIHC cis rs6964587 0.810 rs408 chr7:91556284 A/G cg17063962 chr7:91808500 NA -0.97 -18.17 -0.7 4.14e-52 Breast cancer; LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg03785755 chr6:26196794 NA 0.51 5.97 0.31 5.8e-9 Gout;Renal underexcretion gout; LIHC cis rs8060686 0.641 rs112099181 chr16:68154230 T/C cg05110241 chr16:68378359 PRMT7 -0.57 -6.64 -0.34 1.27e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs2197308 0.643 rs1842597 chr12:37862142 C/G cg26384229 chr12:38710491 ALG10B -0.5 -6.94 -0.35 1.97e-11 Morning vs. evening chronotype; LIHC cis rs11711311 1.000 rs2305546 chr3:113503354 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.2 0.41 5.04e-15 IgG glycosylation; LIHC cis rs6963495 0.818 rs818619 chr7:105172505 A/T cg19920283 chr7:105172520 RINT1 0.77 8.55 0.42 4.13e-16 Bipolar disorder (body mass index interaction); LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg14630369 chr13:100803190 PCCA -0.38 -6.41 -0.33 4.83e-10 Pain; LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.18 -0.32 1.78e-9 Total body bone mineral density; LIHC cis rs35306767 0.761 rs12771539 chr10:1050653 A/G cg26597838 chr10:835615 NA 0.9 8.69 0.43 1.54e-16 Eosinophil percentage of granulocytes; LIHC trans rs10411161 0.752 rs8107388 chr19:52407286 C/A cg22319618 chr22:45562946 NUP50 -0.56 -7.0 -0.35 1.37e-11 Breast cancer; LIHC cis rs12286929 0.617 rs11607928 chr11:115102224 A/G cg04055981 chr11:115044050 NA 0.43 6.14 0.32 2.31e-9 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7617773 0.817 rs6791930 chr3:48329900 A/G cg11946769 chr3:48343235 NME6 0.87 11.29 0.52 2.49e-25 Coronary artery disease; LIHC cis rs67311347 0.869 rs7646899 chr3:40366982 A/G cg00656387 chr3:40428638 ENTPD3 0.43 6.96 0.35 1.75e-11 Renal cell carcinoma; LIHC cis rs12477438 0.798 rs2123686 chr2:99690135 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.7 -0.5 3.03e-23 Chronic sinus infection; LIHC cis rs11792861 0.619 rs2289481 chr9:111712924 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.69 11.42 0.53 8.18e-26 Menarche (age at onset); LIHC cis rs769267 0.930 rs2288852 chr19:19605348 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.94 0.31 7.05e-9 Tonsillectomy; LIHC cis rs9549367 0.789 rs9549711 chr13:113900557 C/T cg18105134 chr13:113819100 PROZ -0.68 -11.64 -0.53 1.29e-26 Platelet distribution width; LIHC cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg18404041 chr3:52824283 ITIH1 -0.54 -8.61 -0.42 2.76e-16 Bipolar disorder; LIHC cis rs3096299 0.559 rs9931073 chr16:89568513 G/C cg00750074 chr16:89608354 SPG7 -0.4 -6.32 -0.32 8.04e-10 Multiple myeloma (IgH translocation); LIHC cis rs2153535 0.584 rs9502723 chr6:8541504 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.33 0.41 2.02e-15 Motion sickness; LIHC cis rs9457247 0.534 rs4710149 chr6:167386346 T/C cg12798992 chr6:167411361 FGFR1OP -0.48 -7.79 -0.39 8.26e-14 Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09844907 chr16:15489619 MPV17L 0.65 8.74 0.43 1.04e-16 Lung function (FEV1/FVC); LIHC trans rs61931739 0.500 rs7965421 chr12:34523624 G/T cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs6062302 0.522 rs13038448 chr20:62218453 C/T cg09650180 chr20:62225654 GMEB2 -0.37 -5.77 -0.3 1.78e-8 Glioblastoma; LIHC trans rs13113376 0.517 rs9307624 chr4:131242185 A/G cg22022747 chr1:209237649 NA 0.28 6.04 0.31 3.94e-9 Intelligence; LIHC cis rs9399135 0.935 rs11759999 chr6:135370495 G/T cg22676075 chr6:135203613 NA 0.41 6.5 0.33 2.93e-10 Red blood cell count; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg06873352 chr17:61820015 STRADA 0.6 9.28 0.45 1.99e-18 Height; LIHC cis rs7192750 0.586 rs4788585 chr16:71993638 A/G cg06353428 chr16:71660113 MARVELD3 0.81 9.13 0.44 6.3e-18 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg04267008 chr7:1944627 MAD1L1 -0.61 -9.49 -0.46 4.07e-19 Bipolar disorder and schizophrenia; LIHC cis rs16828019 0.852 rs12729586 chr1:41522377 C/A cg03387723 chr1:41708464 SCMH1 -0.4 -6.46 -0.33 3.63e-10 Intelligence (multi-trait analysis); LIHC cis rs4908768 0.906 rs11121182 chr1:8522553 G/T cg20416874 chr1:8611966 RERE 0.56 8.72 0.43 1.25e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs17106184 1.000 rs12085666 chr1:51391569 A/G cg07174182 chr1:51127561 FAF1 -0.75 -8.32 -0.41 2.05e-15 Type 2 diabetes; LIHC cis rs9837602 0.529 rs793459 chr3:99520591 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.97 0.35 1.59e-11 Breast cancer; LIHC cis rs7116495 1.000 rs2511076 chr11:71783827 A/G cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs2479724 1.000 rs2254479 chr6:41831143 G/A cg17623882 chr6:41773611 USP49 -0.54 -8.22 -0.41 4.17e-15 Menarche (age at onset); LIHC cis rs929354 0.707 rs1182445 chr7:157024428 C/G cg16102536 chr7:156981717 UBE3C -0.35 -5.88 -0.3 9.69e-9 Body mass index; LIHC cis rs7116495 0.609 rs501308 chr11:71581325 C/G cg26138937 chr11:71823887 C11orf51 1.25 9.95 0.47 1.18e-20 Severe influenza A (H1N1) infection; LIHC cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg06634786 chr22:41940651 POLR3H 0.75 7.79 0.39 7.89e-14 Vitiligo; LIHC cis rs6088590 0.561 rs11167239 chr20:33140472 G/A cg08999081 chr20:33150536 PIGU 0.69 13.69 0.59 2.65e-34 Coronary artery disease; LIHC cis rs6448317 0.556 rs4697076 chr4:24908601 G/A cg21108841 chr4:24914750 CCDC149 0.53 6.57 0.33 1.92e-10 Heschl's gyrus morphology; LIHC trans rs1005277 0.579 rs2474580 chr10:38398713 G/A cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7927771 0.894 rs12798346 chr11:47583121 C/T cg20135002 chr11:47629003 NA -0.57 -10.06 -0.48 5.2e-21 Subjective well-being; LIHC trans rs10242455 0.702 rs73711280 chr7:99039604 C/T cg09045935 chr12:6379348 NA 0.83 6.85 0.35 3.36e-11 Blood metabolite levels; LIHC cis rs17826219 0.706 rs609472 chr17:28951427 T/C cg14067834 chr17:29058358 SUZ12P 0.62 6.24 0.32 1.28e-9 Body mass index; LIHC cis rs240764 0.658 rs1336251 chr6:101247698 C/T cg09795085 chr6:101329169 ASCC3 -0.42 -5.83 -0.3 1.31e-8 Neuroticism; LIHC cis rs918629 0.798 rs6898399 chr5:95289398 A/G cg10483112 chr5:95245456 ELL2 -0.37 -6.41 -0.33 4.82e-10 IgG glycosylation; LIHC cis rs7917772 0.503 rs1536308 chr10:104288777 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00628130 chr8:95908808 CCNE2 -0.44 -6.32 -0.32 7.98e-10 Cognitive function; LIHC cis rs734999 0.545 rs6698817 chr1:2564183 T/C cg18854424 chr1:2615690 NA -0.33 -7.13 -0.36 6.07e-12 Ulcerative colitis; LIHC cis rs7131987 0.509 rs11050173 chr12:29441473 T/A cg00204748 chr12:29376779 FAR2 0.37 6.31 0.32 8.87e-10 QT interval; LIHC cis rs4689592 0.619 rs3796908 chr4:7061378 G/A cg06697600 chr4:7070879 GRPEL1 -0.66 -10.72 -0.5 2.57e-23 Monocyte percentage of white cells; LIHC cis rs4908768 0.501 rs35865480 chr1:8603777 C/T cg20416874 chr1:8611966 RERE -0.7 -15.08 -0.63 9.46e-40 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg04546413 chr19:29218101 NA 0.56 10.17 0.48 2.16e-21 Methadone dose in opioid dependence; LIHC cis rs903552 0.736 rs9806369 chr15:102008430 A/C cg19295451 chr15:102010161 PCSK6 -0.57 -7.96 -0.4 2.64e-14 Diabetic kidney disease; LIHC cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg06481639 chr22:41940642 POLR3H -0.63 -5.95 -0.31 6.7e-9 Vitiligo; LIHC cis rs9486715 0.830 rs2475023 chr6:96996833 G/A cg06623918 chr6:96969491 KIAA0776 -0.87 -15.59 -0.64 9.19e-42 Headache; LIHC cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg01765077 chr12:122356316 WDR66 0.57 7.63 0.38 2.4e-13 Mean corpuscular volume; LIHC cis rs6808694 0.568 rs3913938 chr3:20221698 G/A cg00235661 chr3:20228976 SGOL1 0.37 6.51 0.33 2.74e-10 Ischemic stroke; LIHC cis rs965469 1.000 rs6037547 chr20:3299228 C/A cg25506879 chr20:3388711 C20orf194 -0.57 -6.83 -0.35 3.86e-11 IFN-related cytopenia; LIHC cis rs1348850 0.567 rs3770009 chr2:178536544 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.81 0.39 6.86e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs227584 0.663 rs3180912 chr17:42259463 A/G cg16434002 chr17:42200994 HDAC5 -0.4 -5.87 -0.3 1.03e-8 Bone mineral density (hip);Bone mineral density; LIHC trans rs7558233 0.614 rs4665214 chr2:23678795 A/G cg27615363 chr5:174120078 NA 0.41 6.08 0.31 3.17e-9 Cannabis use (initiation); LIHC cis rs2562152 0.744 rs1045001 chr16:107275 G/T cg02949481 chr16:131562 MPG -0.45 -7.04 -0.36 1.03e-11 Glioblastoma; LIHC cis rs1461503 0.966 rs10790546 chr11:122838426 C/A cg14473756 chr11:122847823 NA -0.37 -6.67 -0.34 1.02e-10 Menarche (age at onset); LIHC cis rs7927592 0.912 rs55767696 chr11:68375120 C/G cg01657329 chr11:68192670 LRP5 -0.48 -6.3 -0.32 9.02e-10 Total body bone mineral density; LIHC cis rs8180040 0.966 rs56351005 chr3:47430186 G/T cg27129171 chr3:47204927 SETD2 -0.58 -9.8 -0.47 3.94e-20 Colorectal cancer; LIHC cis rs875971 0.660 rs801217 chr7:66010577 C/T cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.72 0.3 2.32e-8 Menopause (age at onset); LIHC cis rs2455799 0.634 rs11128764 chr3:15902836 G/C cg12698662 chr3:15914712 MIR563 -0.4 -7.51 -0.38 5.11e-13 Mean platelet volume; LIHC cis rs11711311 1.000 rs62268169 chr3:113493860 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.23 0.45 2.8e-18 IgG glycosylation; LIHC cis rs10751667 0.600 rs11246376 chr11:999622 C/T cg10932868 chr11:921992 NA 0.33 6.26 0.32 1.16e-9 Alzheimer's disease (late onset); LIHC cis rs11190604 0.767 rs11190513 chr10:102165238 A/G cg07080220 chr10:102295463 HIF1AN 0.46 6.36 0.33 6.32e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs644799 0.562 rs1313288 chr11:95520695 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.67 11.02 0.51 2.34e-24 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3099143 1.000 rs1398241 chr15:77153386 C/T cg21673338 chr15:77095150 SCAPER -0.48 -7.57 -0.38 3.58e-13 Recalcitrant atopic dermatitis; LIHC cis rs4555082 0.915 rs79048296 chr14:105754944 G/A cg13114125 chr14:105738426 BRF1 -0.73 -9.68 -0.46 9.26e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs6931421 1.000 rs6931421 chr6:80880138 A/C cg08355045 chr6:80787529 NA 0.32 6.09 0.31 3e-9 Sitting height ratio; LIHC cis rs12477438 0.765 rs4851183 chr2:99629149 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.65 -0.38 2.08e-13 Chronic sinus infection; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11600697 chr3:37034814 EPM2AIP1;MLH1 -0.48 -6.1 -0.31 2.92e-9 Systolic blood pressure; LIHC cis rs4407350 0.756 rs131158 chr22:44891873 A/G cg26276947 chr22:44892394 LDOC1L 0.32 6.1 0.31 2.87e-9 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs4780401 0.933 rs11075010 chr16:11826013 C/T cg01061890 chr16:11836724 TXNDC11 -0.41 -6.04 -0.31 4.13e-9 Rheumatoid arthritis; LIHC cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg08392591 chr16:89556376 ANKRD11 0.56 9.06 0.44 1.03e-17 Multiple myeloma (IgH translocation); LIHC cis rs10791097 0.967 rs4366492 chr11:130717256 T/C cg12179176 chr11:130786555 SNX19 0.62 9.58 0.46 2.06e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs708547 0.624 rs1718886 chr4:57849251 C/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.69 12.38 0.56 2.49e-29 Response to bleomycin (chromatid breaks); LIHC cis rs1577917 0.958 rs884842 chr6:86680397 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.55 -0.33 2.1e-10 Response to antipsychotic treatment; LIHC cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg12373951 chr3:133503437 NA 0.74 13.69 0.59 2.56e-34 Iron status biomarkers; LIHC cis rs12478296 1.000 rs56292923 chr2:243039986 C/T cg18898632 chr2:242989856 NA -0.56 -7.47 -0.37 6.72e-13 Obesity-related traits; LIHC cis rs9517320 0.534 rs3858776 chr13:99161457 C/T cg20487152 chr13:99095054 FARP1 -0.36 -6.11 -0.31 2.72e-9 Longevity; LIHC trans rs7618501 0.521 rs6774354 chr3:49961780 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.76 0.34 5.98e-11 Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26915774 chr2:162094867 NA -0.48 -6.08 -0.31 3.17e-9 Systolic blood pressure; LIHC cis rs9513627 0.512 rs9517759 chr13:100180108 T/G cg15490075 chr13:100150979 NA 0.8 12.02 0.54 5.38e-28 Obesity-related traits; LIHC cis rs10464366 0.746 rs6945402 chr7:39145385 A/T cg10621924 chr7:39171070 POU6F2 0.43 6.6 0.34 1.57e-10 IgG glycosylation; LIHC cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8044868 0.530 rs12932845 chr16:72122765 G/A cg16558253 chr16:72132732 DHX38 -0.4 -6.75 -0.34 6.34e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs758324 0.947 rs683749 chr5:131283376 C/T cg06307176 chr5:131281290 NA -0.4 -5.83 -0.3 1.3e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs875971 0.862 rs1860469 chr7:66106875 A/G cg18876405 chr7:65276391 NA -0.32 -5.86 -0.3 1.08e-8 Aortic root size; LIHC cis rs1008375 0.966 rs3775923 chr4:17585625 T/C cg02297831 chr4:17616191 MED28 0.44 6.05 0.31 3.83e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs1355223 0.583 rs2956074 chr11:34864880 T/C cg06937548 chr11:34938143 PDHX;APIP 0.42 5.88 0.3 9.5e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg23809679 chr4:71554125 UTP3 -0.46 -6.04 -0.31 3.96e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9911578 0.757 rs4793954 chr17:56629527 G/T cg05425664 chr17:57184151 TRIM37 0.5 7.05 0.36 9.94e-12 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg22800045 chr5:56110881 MAP3K1 0.68 8.6 0.42 2.87e-16 Initial pursuit acceleration; LIHC cis rs7619427 1.000 rs6804901 chr3:44066663 G/A cg24966902 chr3:44043705 NA 0.55 7.79 0.39 8.19e-14 Schizophrenia; LIHC cis rs8180040 1.000 rs1638676 chr3:47327651 A/G cg27129171 chr3:47204927 SETD2 0.64 11.01 0.51 2.46e-24 Colorectal cancer; LIHC cis rs9402673 0.517 rs978036 chr6:135342903 C/T cg22676075 chr6:135203613 NA 0.4 6.41 0.33 4.74e-10 Reticulocyte count;High light scatter reticulocyte count; LIHC cis rs7428 0.527 rs1554110 chr2:85547963 C/T cg24342717 chr2:85555507 TGOLN2 -0.79 -10.2 -0.48 1.67e-21 Ear protrusion; LIHC cis rs6754311 0.593 rs55825471 chr2:136526981 T/A cg07169764 chr2:136633963 MCM6 -0.69 -9.92 -0.47 1.45e-20 Mosquito bite size; LIHC cis rs311392 0.967 rs4463399 chr8:55089449 T/C cg11783602 chr8:55087084 NA -0.31 -6.15 -0.32 2.19e-9 Pelvic organ prolapse (moderate/severe); LIHC trans rs9951602 0.512 rs4799248 chr18:76653459 G/A cg02800362 chr5:177631904 HNRNPAB 0.65 10.42 0.49 2.98e-22 Obesity-related traits; LIHC cis rs7296418 0.961 rs1790106 chr12:123591596 G/T cg05973401 chr12:123451056 ABCB9 0.49 7.72 0.39 1.32e-13 Platelet count; LIHC cis rs727505 0.954 rs2170352 chr7:124605584 G/A cg23710748 chr7:124431027 NA -0.34 -6.04 -0.31 4.07e-9 Lewy body disease; LIHC cis rs12220238 0.915 rs10824197 chr10:76282793 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.05 0.31 3.85e-9 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs72960926 0.744 rs11755740 chr6:74934131 C/T cg07247405 chr1:2484626 LOC115110 0.56 6.7 0.34 8.8e-11 Metabolite levels (MHPG); LIHC cis rs7772486 0.790 rs2254283 chr6:146204289 T/C cg05347473 chr6:146136440 FBXO30 0.37 6.03 0.31 4.29e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6089829 0.889 rs6090206 chr20:61668363 G/A cg03213289 chr20:61660250 NA 0.5 8.96 0.44 2.21e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs11711311 1.000 rs9865435 chr3:113450046 G/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.05 -0.36 9.75e-12 IgG glycosylation; LIHC cis rs7772486 0.686 rs9403746 chr6:146103768 C/A cg23711669 chr6:146136114 FBXO30 -0.72 -12.96 -0.57 1.61e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088580 0.634 rs6120669 chr20:33105028 T/C cg08999081 chr20:33150536 PIGU 0.67 13.47 0.59 1.73e-33 Glomerular filtration rate (creatinine); LIHC cis rs711245 0.637 rs11894187 chr2:36781708 T/A cg10546459 chr2:36825355 FEZ2 0.49 5.86 0.3 1.07e-8 Height; LIHC cis rs1904096 0.506 rs4558832 chr4:95148042 G/A cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.06 -0.44 1.02e-17 Type 2 diabetes; LIHC cis rs644799 1.000 rs474442 chr11:95583995 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.65 9.28 0.45 1.98e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4819052 0.788 rs2236449 chr21:46702506 C/T cg20896738 chr21:46707857 POFUT2;LOC642852 0.44 5.85 0.3 1.14e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6089584 1.000 rs6089585 chr20:60564395 G/A cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs1048238 0.525 rs848214 chr1:16265422 A/G cg00529422 chr1:16285251 ZBTB17 0.33 6.34 0.32 7.35e-10 Systolic blood pressure; LIHC cis rs2836974 0.644 rs7281853 chr21:40693490 A/G cg17971929 chr21:40555470 PSMG1 -0.45 -6.72 -0.34 7.63e-11 Cognitive function; LIHC cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg00091569 chr3:40428383 ENTPD3 0.38 6.58 0.34 1.82e-10 Renal cell carcinoma; LIHC cis rs12701220 0.842 rs10236293 chr7:1032637 G/A cg04498913 chr7:1135747 C7orf50 0.39 5.72 0.3 2.27e-8 Bronchopulmonary dysplasia; LIHC trans rs1814175 0.817 rs10128730 chr11:50023369 G/T cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs3099143 1.000 rs1114717 chr15:77086078 A/G cg21673338 chr15:77095150 SCAPER 0.47 7.25 0.36 2.82e-12 Recalcitrant atopic dermatitis; LIHC cis rs9611565 0.546 rs5758430 chr22:42109844 G/T cg06634786 chr22:41940651 POLR3H 0.59 6.39 0.33 5.54e-10 Vitiligo; LIHC cis rs1127311 1.000 rs1127311 chr1:154556663 G/A cg17218026 chr1:154582156 ADAR 0.34 6.55 0.33 2.18e-10 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs7618501 1.000 rs34451146 chr3:49813013 C/T cg21467203 chr3:49911342 NA -0.41 -7.09 -0.36 7.66e-12 Intelligence (multi-trait analysis); LIHC cis rs28489187 0.683 rs233093 chr1:85823120 C/T cg16011679 chr1:85725395 C1orf52 0.45 5.81 0.3 1.42e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs332507 0.830 rs10804562 chr3:124377196 C/T cg05980111 chr3:124395277 KALRN 0.37 6.17 0.32 1.97e-9 Plateletcrit; LIHC trans rs11098499 0.954 rs6857105 chr4:120222298 C/G cg25214090 chr10:38739885 LOC399744 0.55 8.51 0.42 5.65e-16 Corneal astigmatism; LIHC cis rs2540917 0.657 rs11125840 chr2:60627402 G/C cg00543073 chr2:60773386 BCL11A -0.33 -6.57 -0.33 1.87e-10 Mean corpuscular volume; LIHC cis rs7712401 0.791 rs10063253 chr5:122128711 T/C cg18764291 chr5:122110994 SNX2 0.37 6.28 0.32 1.01e-9 Mean platelet volume; LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg12034118 chr1:209979487 IRF6 0.38 5.76 0.3 1.85e-8 Cleft lip with or without cleft palate; LIHC cis rs2576037 0.526 rs2010834 chr18:44560875 C/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.7 -10.99 -0.51 2.84e-24 Personality dimensions; LIHC cis rs9522267 0.535 rs9522286 chr13:112230909 A/G cg10483660 chr13:112241077 NA -0.22 -5.88 -0.3 9.86e-9 Hepatitis; LIHC trans rs3780486 0.813 rs3780488 chr9:33133812 T/C cg20290983 chr6:43655470 MRPS18A 1.19 30.89 0.86 5.55e-101 IgG glycosylation; LIHC cis rs1348850 0.914 rs4893950 chr2:178304885 T/C cg27490568 chr2:178487706 NA 0.37 5.8 0.3 1.52e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs61931739 0.534 rs2636082 chr12:34061848 T/A cg26384229 chr12:38710491 ALG10B 0.47 6.62 0.34 1.36e-10 Morning vs. evening chronotype; LIHC trans rs916888 0.821 rs199525 chr17:44847834 T/G cg13957321 chr17:43675089 NA 0.5 7.69 0.38 1.62e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs3758785 0.679 rs13447595 chr11:94222690 A/G cg21580213 chr11:94231278 ANKRD49 -0.36 -6.23 -0.32 1.36e-9 Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy); LIHC cis rs5769707 0.837 rs5770599 chr22:50019981 C/G cg01652190 chr22:50026171 C22orf34 -0.31 -6.99 -0.35 1.42e-11 Monocyte count;Monocyte percentage of white cells; LIHC trans rs7246657 1.000 rs1823061 chr19:37800626 G/A cg10208301 chr11:6592745 DNHD1 0.48 6.35 0.32 6.68e-10 Coronary artery calcification; LIHC cis rs12971120 0.947 rs4891559 chr18:72170397 C/T cg25817165 chr18:72167213 CNDP2 -0.69 -12.86 -0.57 3.75e-31 Refractive error; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg26338869 chr17:61819248 STRADA 0.6 8.34 0.41 1.89e-15 Prudent dietary pattern; LIHC cis rs7914558 1.000 rs7071373 chr10:104771922 A/G cg04362960 chr10:104952993 NT5C2 0.38 5.75 0.3 1.93e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs3121446 0.889 rs3104041 chr6:107141728 A/G cg26014185 chr6:10033784 NA 0.2 6.18 0.32 1.83e-9 Daytime sleep phenotypes; LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs8114671 0.527 rs6060112 chr20:33489276 A/T cg07148914 chr20:33460835 GGT7 0.65 9.77 0.47 4.93e-20 Height; LIHC cis rs2302190 0.882 rs3803751 chr17:56650356 A/G cg05425664 chr17:57184151 TRIM37 -0.46 -5.79 -0.3 1.58e-8 Vitamin D levels; LIHC trans rs8073060 0.586 rs35542792 chr17:33903886 A/G cg19694781 chr19:47549865 TMEM160 1.24 12.8 0.57 6.47e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs11098499 0.710 rs4145952 chr4:120155806 C/A cg09307838 chr4:120376055 NA 0.59 8.96 0.44 2.21e-17 Corneal astigmatism; LIHC cis rs7845219 0.544 rs7016078 chr8:95922615 G/A cg13393036 chr8:95962371 TP53INP1 -0.32 -6.13 -0.31 2.36e-9 Type 2 diabetes; LIHC cis rs1707322 1.000 rs785504 chr1:46595696 C/T cg03146154 chr1:46216737 IPP -0.45 -7.21 -0.36 3.58e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg06873352 chr17:61820015 STRADA 0.72 12.14 0.55 1.85e-28 Prudent dietary pattern; LIHC trans rs1814175 0.754 rs28663627 chr11:50048829 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC trans rs6011368 0.840 rs2427638 chr20:62900717 C/T cg13869341 chr1:15865 WASH5P 0.43 7.48 0.37 6.26e-13 Clozapine-induced cytotoxicity; LIHC cis rs9814567 0.712 rs9838119 chr3:134331980 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6456156 0.792 rs4710183 chr6:167514083 A/G cg07741184 chr6:167504864 NA -0.3 -7.57 -0.38 3.49e-13 Primary biliary cholangitis; LIHC cis rs875971 0.638 rs3898855 chr7:66036398 G/C cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC cis rs9457247 0.765 rs9459836 chr6:167419105 G/A cg07741184 chr6:167504864 NA 0.31 7.28 0.37 2.35e-12 Crohn's disease; LIHC cis rs2760061 0.626 rs2313118 chr1:228118084 T/C cg01200585 chr1:228362443 C1orf69 -0.4 -5.82 -0.3 1.34e-8 Diastolic blood pressure; LIHC cis rs9467773 0.967 rs6924865 chr6:26521353 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.62 0.59 4.85e-34 Intelligence (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20036162 chr8:67404651 C8orf46 -0.39 -7.24 -0.36 2.92e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.35 0.32 6.81e-10 Gut microbiome composition (summer); LIHC cis rs6860806 0.631 rs6863548 chr5:131575920 G/A cg24060327 chr5:131705240 SLC22A5 -0.45 -5.85 -0.3 1.18e-8 Breast cancer; LIHC cis rs7572733 0.534 rs4850813 chr2:198775982 C/T cg10820045 chr2:198174542 NA -0.47 -7.2 -0.36 3.92e-12 Dermatomyositis; LIHC cis rs8141529 0.732 rs5762784 chr22:29171298 C/T cg02153584 chr22:29168773 CCDC117 0.58 9.31 0.45 1.63e-18 Lymphocyte counts; LIHC cis rs4474465 0.920 rs10899532 chr11:78208470 T/G cg27205649 chr11:78285834 NARS2 0.4 6.24 0.32 1.33e-9 Alzheimer's disease (survival time); LIHC cis rs9649465 1.000 rs3807635 chr7:123382152 A/C cg03229431 chr7:123269106 ASB15 -0.37 -7.89 -0.39 4.16e-14 Migraine; LIHC cis rs12477438 0.501 rs6751927 chr2:99740175 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC cis rs2404602 0.569 rs283793 chr15:76774752 G/A cg23625390 chr15:77176239 SCAPER 0.47 7.72 0.39 1.27e-13 Blood metabolite levels; LIHC cis rs9309711 0.736 rs28619526 chr2:3496804 T/C cg10845886 chr2:3471009 TTC15 -0.52 -8.95 -0.44 2.38e-17 Neurofibrillary tangles; LIHC cis rs11098499 0.691 rs9307471 chr4:120261262 G/A cg09307838 chr4:120376055 NA 0.62 9.89 0.47 1.93e-20 Corneal astigmatism; LIHC cis rs9649213 0.555 rs6956686 chr7:97997945 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs8017423 0.967 rs1959002 chr14:90670994 T/A cg04374321 chr14:90722782 PSMC1 0.71 13.53 0.59 1.03e-33 Mortality in heart failure; LIHC cis rs2153535 0.580 rs9379216 chr6:8481235 G/A cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs11229555 0.645 rs11229462 chr11:58209931 A/T cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.52e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs798554 0.660 rs2644274 chr7:2854380 A/T cg19717773 chr7:2847554 GNA12 -0.43 -7.63 -0.38 2.36e-13 Height; LIHC cis rs7208859 0.673 rs73271887 chr17:29154935 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.0 0.4 1.9e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600626 0.636 rs11236516 chr11:75451668 C/T cg24262691 chr11:75473276 NA -0.41 -6.04 -0.31 4e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs2404602 0.655 rs34748201 chr15:77221530 G/T cg03037974 chr15:76606532 NA 0.72 13.98 0.6 1.88e-35 Blood metabolite levels; LIHC cis rs1046896 0.628 rs12452314 chr17:80723362 A/G cg22325292 chr17:80708367 FN3K 0.39 6.13 0.31 2.49e-9 Glycated hemoglobin levels; LIHC cis rs1707322 0.721 rs61784796 chr1:46163256 A/G cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.686 rs1084086 chr1:46041100 A/C cg24296786 chr1:45957014 TESK2 0.41 5.72 0.3 2.39e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1144333 1.000 rs1340684 chr1:76471146 T/C cg22875332 chr1:76189707 ACADM 0.4 6.26 0.32 1.18e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs35306767 0.668 rs72760914 chr10:1070952 A/G cg26597838 chr10:835615 NA 0.61 6.76 0.34 5.94e-11 Eosinophil percentage of granulocytes; LIHC cis rs6964587 0.967 rs6465341 chr7:91596121 G/C cg17063962 chr7:91808500 NA 1.02 19.55 0.73 1.15e-57 Breast cancer; LIHC cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11122272 0.735 rs2808583 chr1:231512587 G/C cg06096015 chr1:231504339 EGLN1 0.51 9.32 0.45 1.43e-18 Hemoglobin concentration; LIHC cis rs7107174 1.000 rs2256051 chr11:77920457 G/A cg02023728 chr11:77925099 USP35 0.44 8.15 0.4 7.11e-15 Testicular germ cell tumor; LIHC cis rs2637266 0.756 rs846609 chr10:78551718 A/G cg18941641 chr10:78392320 NA 0.27 5.85 0.3 1.14e-8 Pulmonary function; LIHC cis rs9902453 0.791 rs3115100 chr17:28045744 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 13.59 0.59 6.14e-34 Coffee consumption (cups per day); LIHC cis rs1986734 0.576 rs4493564 chr4:77420407 A/G cg24201034 chr4:77507246 SHROOM3 -0.37 -5.88 -0.3 9.68e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs9486719 0.901 rs760619 chr6:96857431 A/G cg06623918 chr6:96969491 KIAA0776 0.7 6.74 0.34 6.64e-11 Migraine;Coronary artery disease; LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg09455208 chr3:40491958 NA 0.41 8.27 0.41 2.99e-15 Renal cell carcinoma; LIHC cis rs8114671 0.562 rs6088635 chr20:33466501 A/G cg07148914 chr20:33460835 GGT7 0.65 9.91 0.47 1.6e-20 Height; LIHC cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg00149659 chr3:10157352 C3orf10 -0.65 -7.01 -0.35 1.3e-11 Alzheimer's disease; LIHC cis rs694739 1.000 rs1783521 chr11:64106291 T/C cg02228329 chr11:64053129 BAD;GPR137 0.7 10.28 0.49 8.98e-22 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs1814175 0.645 rs11040703 chr11:50024961 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs2067615 0.579 rs6539283 chr12:107222989 C/T cg15890332 chr12:107067104 RFX4 0.25 5.81 0.3 1.43e-8 Heart rate; LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC cis rs7927592 0.956 rs12365160 chr11:68250419 A/G cg01657329 chr11:68192670 LRP5 -0.45 -5.9 -0.3 8.7e-9 Total body bone mineral density; LIHC cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg06634786 chr22:41940651 POLR3H 0.74 7.67 0.38 1.78e-13 Vitiligo; LIHC cis rs875971 1.000 rs6970030 chr7:65968679 T/C cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.64e-11 Aortic root size; LIHC cis rs17106184 1.000 rs2105211 chr1:51299810 G/C cg07174182 chr1:51127561 FAF1 -0.63 -7.19 -0.36 4.13e-12 Type 2 diabetes; LIHC cis rs12477438 0.520 rs1453563 chr2:99720267 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.8 0.5 1.35e-23 Chronic sinus infection; LIHC cis rs9783347 1.000 rs59150578 chr11:18340862 G/A cg15585147 chr11:18324498 HPS5 0.38 6.06 0.31 3.69e-9 Pancreatic cancer; LIHC cis rs6062509 1.000 rs6062509 chr20:62362563 G/T cg03999872 chr20:62272968 STMN3 0.41 6.08 0.31 3.19e-9 Prostate cancer; LIHC cis rs922107 0.664 rs1459637 chr1:90040758 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.6 -0.38 2.8e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs12188164 0.543 rs2434694 chr5:462734 C/T cg26072250 chr5:443457 EXOC3;C5orf55 0.47 7.07 0.36 8.74e-12 Cystic fibrosis severity; LIHC cis rs2304069 0.545 rs13168011 chr5:149392377 C/T cg12661370 chr5:149340060 SLC26A2 0.55 8.24 0.41 3.7e-15 HIV-1 control; LIHC cis rs7131987 0.650 rs16934135 chr12:29483963 T/G cg12903224 chr12:29470962 FAR2 -0.41 -6.67 -0.34 1.01e-10 QT interval; LIHC cis rs11758351 0.587 rs10484436 chr6:26237155 C/T cg16070018 chr6:26224392 HIST1H3E 0.6 7.2 0.36 3.79e-12 Gout;Renal underexcretion gout; LIHC cis rs7520050 0.966 rs785481 chr1:46554518 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.8 0.3 1.5e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2243480 1.000 rs67536397 chr7:65947917 G/A cg18252515 chr7:66147081 NA -1.3 -16.7 -0.67 3.38e-46 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg09455208 chr3:40491958 NA 0.37 7.42 0.37 9.12e-13 Renal cell carcinoma; LIHC cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg00149659 chr3:10157352 C3orf10 0.6 6.58 0.33 1.82e-10 Alzheimer's disease; LIHC cis rs7511006 0.893 rs2038049 chr22:50654888 G/C cg07895657 chr22:50616420 PANX2 -0.39 -6.94 -0.35 1.99e-11 Obesity-related traits; LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg00091569 chr3:40428383 ENTPD3 -0.4 -6.79 -0.34 4.83e-11 Renal cell carcinoma; LIHC cis rs10927875 0.597 rs61782184 chr1:16150976 G/A cg21385522 chr1:16154831 NA -1.05 -16.92 -0.68 4.2e-47 Dilated cardiomyopathy; LIHC cis rs734999 0.870 rs2147905 chr1:2482921 C/T cg18854424 chr1:2615690 NA -0.32 -6.7 -0.34 8.49e-11 Ulcerative colitis; LIHC cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg06466757 chr4:1255808 NA 0.35 5.93 0.31 7.24e-9 Obesity-related traits; LIHC cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.43 -8.0 -0.4 1.92e-14 Total body bone mineral density; LIHC cis rs2279817 0.675 rs1416853 chr1:18024880 G/C cg21791023 chr1:18019539 ARHGEF10L 0.42 6.44 0.33 3.98e-10 Neuroticism; LIHC cis rs2976388 0.578 rs13254358 chr8:143823876 G/A cg24634471 chr8:143751801 JRK -0.43 -5.97 -0.31 5.92e-9 Urinary tract infection frequency; LIHC cis rs2302190 0.882 rs7226008 chr17:56644633 T/C cg05425664 chr17:57184151 TRIM37 -0.46 -5.79 -0.3 1.58e-8 Vitamin D levels; LIHC cis rs523522 0.962 rs2168319 chr12:120933217 C/T cg12219531 chr12:120966889 COQ5 0.66 13.06 0.58 6.55e-32 High light scatter reticulocyte count; LIHC trans rs2727020 0.521 rs7101761 chr11:49598178 G/A cg18944383 chr4:111397179 ENPEP 0.33 7.52 0.38 4.93e-13 Coronary artery disease; LIHC cis rs4742903 0.935 rs10820618 chr9:106960503 T/A cg14250997 chr9:106856677 SMC2 0.35 5.87 0.3 1.01e-8 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs72829446 0.530 rs2301609 chr17:7399866 G/A cg02795151 chr17:7402630 POLR2A 0.52 5.9 0.3 8.95e-9 Androgen levels; LIHC cis rs4474465 1.000 rs10899511 chr11:78170923 T/A cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs35306767 0.761 rs12773961 chr10:1013215 C/G cg26597838 chr10:835615 NA 0.93 8.68 0.42 1.64e-16 Eosinophil percentage of granulocytes; LIHC cis rs7429990 0.896 rs7427648 chr3:48158239 C/T cg11946769 chr3:48343235 NME6 -0.47 -6.23 -0.32 1.35e-9 Educational attainment (years of education); LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.06 0.55 3.69e-28 Prudent dietary pattern; LIHC trans rs12620999 0.838 rs13007071 chr2:238038755 A/G cg15676719 chr1:167598521 RCSD1 -0.37 -6.65 -0.34 1.18e-10 Systemic lupus erythematosus; LIHC cis rs7412746 0.611 rs4970985 chr1:150887442 C/T cg17724175 chr1:150552817 MCL1 -0.38 -7.63 -0.38 2.36e-13 Melanoma; LIHC cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg11645453 chr3:52864694 ITIH4 0.21 5.71 0.3 2.46e-8 Electroencephalogram traits; LIHC cis rs9783347 1.000 rs1520884 chr11:18309700 C/T cg15585147 chr11:18324498 HPS5 -0.42 -6.65 -0.34 1.17e-10 Pancreatic cancer; LIHC cis rs1843834 0.539 rs12694643 chr2:225446603 A/G cg22455342 chr2:225449267 CUL3 0.6 8.83 0.43 5.64e-17 IgE levels in asthmatics (D.p. specific); LIHC trans rs2243480 1.000 rs10247526 chr7:65780696 T/G cg10756647 chr7:56101905 PSPH -1.03 -12.6 -0.56 3.61e-30 Diabetic kidney disease; LIHC cis rs7428 0.545 rs2366404 chr2:85551779 G/A cg24342717 chr2:85555507 TGOLN2 -0.78 -10.99 -0.51 2.79e-24 Ear protrusion; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg00656387 chr3:40428638 ENTPD3 0.48 8.05 0.4 1.36e-14 Renal cell carcinoma; LIHC cis rs7208859 0.673 rs3816780 chr17:29161358 C/T cg14067834 chr17:29058358 SUZ12P 0.63 6.27 0.32 1.11e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7651039 0.641 rs6773682 chr3:15676426 G/A cg16303742 chr3:15540471 COLQ 0.55 9.82 0.47 3.2e-20 Coronary heart disease; LIHC cis rs6088590 0.901 rs6087631 chr20:33403509 T/C cg24642439 chr20:33292090 TP53INP2 0.77 10.49 0.49 1.68e-22 Coronary artery disease; LIHC cis rs8114671 0.805 rs6060168 chr20:33621017 C/T cg07148914 chr20:33460835 GGT7 0.56 8.63 0.42 2.38e-16 Height; LIHC cis rs17253792 0.822 rs77182097 chr14:56136695 G/A cg01858014 chr14:56050164 KTN1 -0.66 -6.75 -0.34 6.43e-11 Putamen volume; LIHC trans rs10411161 0.752 rs4584941 chr19:52392141 C/T cg22319618 chr22:45562946 NUP50 -0.65 -8.52 -0.42 5.07e-16 Breast cancer; LIHC cis rs7487075 0.554 rs7967629 chr12:46628607 C/T cg15584813 chr12:47219626 SLC38A4 0.31 5.79 0.3 1.63e-8 Itch intensity from mosquito bite; LIHC cis rs2153535 0.580 rs2327067 chr6:8518482 C/G cg21535247 chr6:8435926 SLC35B3 0.62 8.22 0.41 4.22e-15 Motion sickness; LIHC cis rs2073499 1.000 rs76846888 chr3:50406058 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 0.82 8.45 0.42 8.78e-16 Schizophrenia; LIHC cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg08499158 chr17:42289980 UBTF -0.51 -8.45 -0.42 8.48e-16 Total body bone mineral density; LIHC cis rs6665290 0.935 rs17528667 chr1:227201770 C/T cg10327440 chr1:227177885 CDC42BPA -1.16 -28.66 -0.84 6.08e-93 Myeloid white cell count; LIHC trans rs1814175 0.754 rs10219245 chr11:49645052 C/T cg18944383 chr4:111397179 ENPEP 0.24 6.14 0.32 2.31e-9 Height; LIHC cis rs4843747 0.518 rs4072777 chr16:88107030 G/A cg06050784 chr16:88016603 BANP 0.36 6.57 0.33 1.93e-10 Menopause (age at onset); LIHC cis rs7959452 0.640 rs10878957 chr12:69699638 G/C cg20891283 chr12:69753455 YEATS4 0.81 15.31 0.64 1.21e-40 Blood protein levels; LIHC cis rs2033711 0.870 rs3764534 chr19:58929136 G/A cg00825309 chr19:58991885 ZNF446 -0.62 -9.59 -0.46 1.87e-19 Uric acid clearance; LIHC cis rs6963495 0.769 rs73192134 chr7:105189338 T/C cg19920283 chr7:105172520 RINT1 0.64 5.82 0.3 1.34e-8 Bipolar disorder (body mass index interaction); LIHC cis rs7674212 0.541 rs2720458 chr4:104052963 C/G cg16532752 chr4:104119610 CENPE -0.42 -6.61 -0.34 1.48e-10 Type 2 diabetes; LIHC cis rs1577917 1.000 rs34281561 chr6:86701872 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.81 -0.47 3.57e-20 Response to antipsychotic treatment; LIHC cis rs916888 0.821 rs70602 chr17:44859715 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs8031584 0.678 rs3122 chr15:31170290 A/T cg08109568 chr15:31115862 NA 0.41 6.49 0.33 3.05e-10 Huntington's disease progression; LIHC cis rs875971 0.619 rs2302918 chr7:66000932 A/G cg00343986 chr7:65444356 GUSB 0.41 6.21 0.32 1.5e-9 Aortic root size; LIHC cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg06108461 chr20:60628389 TAF4 -0.89 -14.15 -0.61 4.18e-36 Body mass index; LIHC cis rs2439831 0.850 rs16965120 chr15:44100342 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.3 0.41 2.45e-15 Lung cancer in ever smokers; LIHC cis rs8016982 1.000 rs12147118 chr14:81652975 A/C cg01989461 chr14:81687754 GTF2A1 -0.59 -11.7 -0.53 7.97e-27 Schizophrenia; LIHC cis rs600806 0.888 rs10858084 chr1:109882250 T/A cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.8 -0.39 7.78e-14 Intelligence (multi-trait analysis); LIHC cis rs7238033 0.624 rs9304323 chr18:43308315 A/G cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs78545713 1.000 rs78661760 chr6:26250033 A/T cg16070018 chr6:26224392 HIST1H3E 0.67 7.14 0.36 5.72e-12 Iron status biomarkers (total iron binding capacity); LIHC cis rs4727027 0.870 rs62507512 chr7:148799338 C/T cg23583168 chr7:148888333 NA -0.7 -9.81 -0.47 3.57e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs3106136 1.000 rs2664871 chr4:95146281 A/G cg11021082 chr4:95130006 SMARCAD1 0.45 8.2 0.41 4.88e-15 Capecitabine sensitivity; LIHC trans rs910316 0.737 rs175045 chr14:75475275 A/C cg10152585 chr3:50297680 NA -0.46 -6.22 -0.32 1.43e-9 Height; LIHC cis rs801193 0.967 rs2707849 chr7:66152712 T/C cg18876405 chr7:65276391 NA 0.43 7.36 0.37 1.34e-12 Aortic root size; LIHC cis rs28830936 0.510 rs7175346 chr15:42100674 G/A cg17847044 chr15:42102381 MAPKBP1 -0.48 -11.7 -0.53 7.69e-27 Diastolic blood pressure; LIHC cis rs9916302 0.904 rs55689507 chr17:37404436 G/C cg03013999 chr17:37608204 MED1 0.35 5.93 0.31 7.32e-9 Glomerular filtration rate (creatinine); LIHC cis rs9457247 1.000 rs408918 chr6:167399282 G/T cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.12e-23 Crohn's disease; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg11494091 chr17:61959527 GH2 0.45 8.06 0.4 1.26e-14 Prudent dietary pattern; LIHC trans rs4146653 0.706 rs10904328 chr10:4772604 G/A cg25345178 chr8:72459908 NA -0.32 -6.08 -0.31 3.26e-9 Major depressive disorder; LIHC cis rs72627123 0.656 rs17096314 chr14:74567952 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.85 8.21 0.41 4.66e-15 Morning vs. evening chronotype; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg14246617 chr3:69788840 MITF -0.46 -6.14 -0.32 2.33e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs11630290 0.736 rs2197259 chr15:64154156 T/C cg12036633 chr15:63758958 NA 0.64 6.12 0.31 2.53e-9 Iris characteristics; LIHC cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC cis rs17817600 0.866 rs12290316 chr11:85644998 T/C cg03102841 chr11:85646010 NA -0.48 -6.27 -0.32 1.06e-9 Alzheimer's disease; LIHC cis rs1355223 0.867 rs11821793 chr11:34681462 A/G cg11058730 chr11:34937778 PDHX;APIP -0.42 -5.76 -0.3 1.83e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs903552 0.736 rs9806369 chr15:102008430 A/C cg00659931 chr15:102010125 PCSK6 -0.53 -7.22 -0.36 3.45e-12 Diabetic kidney disease; LIHC cis rs3770081 1.000 rs735737 chr2:86177101 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -8.82 -0.43 6.02e-17 Facial emotion recognition (sad faces); LIHC cis rs2832191 0.791 rs2832179 chr21:30480366 C/T cg24692254 chr21:30365293 RNF160 -0.7 -12.91 -0.57 2.54e-31 Dental caries; LIHC cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg23205692 chr1:25664452 TMEM50A 0.41 6.62 0.34 1.37e-10 Erythrocyte sedimentation rate; LIHC cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg20887711 chr4:1340912 KIAA1530 0.81 12.84 0.57 4.73e-31 Longevity; LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg07133347 chr1:107600762 PRMT6 0.46 6.9 0.35 2.5e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1003719 0.680 rs2835621 chr21:38510616 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.45e-25 Eye color traits; LIHC cis rs2932538 0.961 rs1238 chr1:113214097 G/A cg22162597 chr1:113214053 CAPZA1 -0.73 -11.18 -0.52 5.9e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs3806843 0.735 rs2530240 chr5:140060547 T/C cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.6e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs34540877 1.000 rs12985259 chr19:33139230 T/G cg22980127 chr19:33182716 NUDT19 1.0 6.63 0.34 1.3e-10 Red cell distribution width; LIHC cis rs6582630 0.502 rs2204008 chr12:38439203 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.48 0.42 6.79e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg05564831 chr3:52568323 NT5DC2 0.35 5.79 0.3 1.59e-8 Bipolar disorder; LIHC cis rs9325144 0.560 rs11183090 chr12:38662293 G/C cg26384229 chr12:38710491 ALG10B -0.48 -7.36 -0.37 1.38e-12 Morning vs. evening chronotype; LIHC cis rs4819052 0.851 rs2838864 chr21:46711474 A/T cg02159808 chr21:46707872 POFUT2;LOC642852 -0.54 -7.84 -0.39 5.69e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1023500 0.551 rs2301521 chr22:42423110 G/C cg04733989 chr22:42467013 NAGA 0.69 9.55 0.46 2.63e-19 Schizophrenia; LIHC cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg18306943 chr3:40428807 ENTPD3 0.34 5.86 0.3 1.07e-8 Renal cell carcinoma; LIHC cis rs9549328 0.800 rs9549619 chr13:113632620 C/G cg18289306 chr13:113640169 MCF2L 0.42 6.67 0.34 1.02e-10 Systolic blood pressure; LIHC cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg27170947 chr2:26402098 FAM59B -0.67 -8.4 -0.41 1.24e-15 Gut microbiome composition (summer); LIHC cis rs3820500 0.585 rs1289954 chr1:117914309 G/A cg20383390 chr1:117909022 MAN1A2 0.44 5.77 0.3 1.79e-8 Pneumonia; LIHC cis rs12477438 0.520 rs6741773 chr2:99738962 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.88 0.6 4.52e-35 Chronic sinus infection; LIHC cis rs7520050 0.751 rs2230657 chr1:46073489 G/A cg03146154 chr1:46216737 IPP -0.47 -7.54 -0.38 4.18e-13 Red blood cell count;Reticulocyte count; LIHC trans rs7939886 0.920 rs10501343 chr11:55759573 G/T cg15704280 chr7:45808275 SEPT13 0.64 6.11 0.31 2.72e-9 Myopia (pathological); LIHC cis rs918629 0.798 rs7705279 chr5:95324375 C/T cg10483112 chr5:95245456 ELL2 -0.36 -6.36 -0.33 6.3e-10 IgG glycosylation; LIHC cis rs262150 0.714 rs2657397 chr7:158785095 C/T cg19418458 chr7:158789849 NA -0.38 -6.44 -0.33 4.06e-10 Facial morphology (factor 20); LIHC cis rs2204008 0.597 rs4002591 chr12:38133841 A/G cg26384229 chr12:38710491 ALG10B 0.83 10.28 0.49 8.84e-22 Bladder cancer; LIHC cis rs950169 1.000 rs12916348 chr15:84765527 C/T cg17507749 chr15:85114479 UBE2QP1 0.76 7.74 0.39 1.14e-13 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg22542420 chr17:43183176 NMT1 0.45 6.05 0.31 3.71e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg22903471 chr2:27725779 GCKR -0.5 -8.51 -0.42 5.64e-16 Total body bone mineral density; LIHC cis rs6500602 0.739 rs4786502 chr16:4537104 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.78 0.3 1.72e-8 Schizophrenia; LIHC cis rs8017423 0.607 rs12885664 chr14:90845697 T/C cg14092571 chr14:90743983 NA 0.42 6.07 0.31 3.47e-9 Mortality in heart failure; LIHC cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.37e-17 Developmental language disorder (linguistic errors); LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.34 0.32 7.32e-10 Menopause (age at onset); LIHC cis rs2710642 0.721 rs12328837 chr2:62896544 G/A cg17519650 chr2:63277830 OTX1 0.48 7.15 0.36 5.33e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg00091569 chr3:40428383 ENTPD3 0.4 6.73 0.34 7.09e-11 Renal cell carcinoma; LIHC cis rs9952991 0.883 rs2847293 chr18:12782448 A/T cg23598886 chr18:12777645 NA 0.46 6.28 0.32 1.01e-9 Inflammatory skin disease; LIHC trans rs7246657 0.882 rs4803539 chr19:37897522 A/C cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs360798 0.553 rs360804 chr2:62939397 C/T cg17519650 chr2:63277830 OTX1 -0.57 -8.98 -0.44 1.82e-17 Coronary artery disease; LIHC cis rs7552404 0.924 rs1146579 chr1:76209792 C/T cg22875332 chr1:76189707 ACADM -0.47 -7.42 -0.37 9.06e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11098499 0.863 rs1383533 chr4:120434576 G/A cg09307838 chr4:120376055 NA 0.77 11.93 0.54 1.14e-27 Corneal astigmatism; LIHC cis rs1008375 0.966 rs3775927 chr4:17599894 G/T cg02297831 chr4:17616191 MED28 0.48 7.3 0.37 2e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6762 0.550 rs8672 chr11:838634 C/G cg15787769 chr11:842744 TSPAN4;POLR2L -0.6 -7.12 -0.36 6.35e-12 Mean platelet volume; LIHC cis rs2070488 1.000 rs13058903 chr3:38513365 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.91 -16.05 -0.66 1.26e-43 Electrocardiographic conduction measures; LIHC cis rs11122272 0.675 rs1416913 chr1:231533206 A/C cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.73e-19 Hemoglobin concentration; LIHC cis rs7845219 0.544 rs2945554 chr8:95939594 C/A cg13393036 chr8:95962371 TP53INP1 -0.3 -5.86 -0.3 1.11e-8 Type 2 diabetes; LIHC cis rs270601 0.770 rs10463891 chr5:131597392 C/T cg24060327 chr5:131705240 SLC22A5 0.53 6.93 0.35 2.07e-11 Acylcarnitine levels; LIHC cis rs10744422 0.925 rs3825143 chr12:123352179 C/T cg07706471 chr12:123319906 HIP1R -0.61 -8.12 -0.4 8.33e-15 Schizophrenia; LIHC cis rs2278034 0.516 rs9829709 chr3:195616673 G/A cg20384732 chr3:195601375 TNK2 -0.4 -6.43 -0.33 4.39e-10 Bronchopulmonary dysplasia; LIHC cis rs40363 0.645 rs250633 chr16:3523002 C/T cg21433313 chr16:3507492 NAT15 0.47 8.58 0.42 3.34e-16 Tuberculosis; LIHC cis rs924607 1.000 rs4045344 chr5:595870 G/T cg04476341 chr5:669733 TPPP -0.41 -9.0 -0.44 1.62e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6964587 0.933 rs28671255 chr7:91770705 A/G cg17063962 chr7:91808500 NA 1.05 21.66 0.76 4.03e-66 Breast cancer; LIHC cis rs10791323 0.511 rs4937837 chr11:133731134 T/C cg06766960 chr11:133703094 NA -0.67 -11.31 -0.52 2.06e-25 Childhood ear infection; LIHC cis rs765787 0.530 rs2413786 chr15:45525394 C/A cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.78 -0.3 1.71e-8 Uric acid levels; LIHC cis rs2404602 0.735 rs11637490 chr15:76759565 A/G cg03037974 chr15:76606532 NA -0.64 -11.4 -0.52 1.01e-25 Blood metabolite levels; LIHC cis rs9916302 0.851 rs2338795 chr17:37399364 T/G cg00129232 chr17:37814104 STARD3 -0.4 -6.37 -0.33 6.17e-10 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.619 rs28502463 chr4:120257023 T/C cg09307838 chr4:120376055 NA 0.7 11.05 0.51 1.72e-24 Corneal astigmatism; LIHC cis rs701145 0.556 rs355751 chr3:153971602 T/C cg16511985 chr3:153974050 SGEF 0.41 8.78 0.43 7.86e-17 Coronary artery disease; LIHC cis rs965469 0.895 rs6037592 chr20:3392950 T/G cg25506879 chr20:3388711 C20orf194 -0.52 -6.19 -0.32 1.71e-9 IFN-related cytopenia; LIHC cis rs2637266 1.000 rs7082587 chr10:78386328 C/T cg18941641 chr10:78392320 NA 0.3 6.52 0.33 2.5e-10 Pulmonary function; LIHC cis rs3862260 0.509 rs3795662 chr1:120165135 G/T cg11530693 chr1:120165357 ZNF697 0.48 7.59 0.38 3.02e-13 Systemic lupus erythematosus; LIHC cis rs17376456 0.877 rs10055340 chr5:93317644 T/C cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs6977660 0.619 rs71526305 chr7:19785374 G/C cg07541023 chr7:19748670 TWISTNB 0.41 6.2 0.32 1.67e-9 Thyroid stimulating hormone; LIHC cis rs11630290 0.592 rs8028348 chr15:64156465 A/G cg12036633 chr15:63758958 NA 0.57 6.09 0.31 3.03e-9 Iris characteristics; LIHC cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg04944784 chr2:26401820 FAM59B -0.71 -9.26 -0.45 2.39e-18 Gut microbiome composition (summer); LIHC cis rs12497850 0.931 rs6442130 chr3:48778027 A/G cg06212747 chr3:49208901 KLHDC8B 0.52 6.38 0.33 5.91e-10 Parkinson's disease; LIHC cis rs7618501 1.000 rs11716575 chr3:49744890 A/G cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs2832191 1.000 rs6516891 chr21:30483070 C/T cg24692254 chr21:30365293 RNF160 -0.64 -11.37 -0.52 1.22e-25 Dental caries; LIHC cis rs9381040 0.610 rs742495 chr6:41018233 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.26 -0.32 1.12e-9 Alzheimer's disease (late onset); LIHC cis rs2073499 0.935 rs3755832 chr3:50305234 G/A cg03645007 chr3:50255295 SLC38A3 0.53 6.59 0.34 1.66e-10 Schizophrenia; LIHC cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg06618935 chr21:46677482 NA -0.3 -5.76 -0.3 1.86e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2153535 0.601 rs1737581 chr6:8539138 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.44 0.53 7.27e-26 Motion sickness; LIHC cis rs7927592 0.763 rs7119422 chr11:68331154 C/T cg01657329 chr11:68192670 LRP5 0.51 7.53 0.38 4.69e-13 Total body bone mineral density; LIHC cis rs769267 0.930 rs7254748 chr19:19397479 A/C cg21559469 chr19:19431446 KIAA0892;SF4 0.41 5.74 0.3 2.09e-8 Tonsillectomy; LIHC cis rs1005277 0.579 rs2474587 chr10:38420666 C/T cg25427524 chr10:38739819 LOC399744 -0.64 -12.28 -0.55 5.86e-29 Extrinsic epigenetic age acceleration; LIHC cis rs35110281 0.782 rs6518309 chr21:45047992 C/A cg04455712 chr21:45112962 RRP1B 0.46 7.39 0.37 1.13e-12 Mean corpuscular volume; LIHC cis rs748404 0.660 rs693510 chr15:43714625 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.1e-13 Lung cancer; LIHC cis rs992157 0.804 rs6758540 chr2:219138625 A/G cg00012203 chr2:219082015 ARPC2 -0.83 -13.05 -0.58 7.16e-32 Colorectal cancer; LIHC cis rs3806843 1.000 rs3822346 chr5:140187322 C/T cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10779751 0.690 rs2791646 chr1:11133242 C/T cg08854313 chr1:11322531 MTOR 0.66 10.0 0.48 7.83e-21 Body mass index; LIHC cis rs317689 0.559 rs710794 chr12:69747177 C/T cg14784868 chr12:69753453 YEATS4 0.66 6.27 0.32 1.09e-9 Response to diuretic therapy; LIHC cis rs9814567 0.929 rs9855013 chr3:134240414 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10838687 0.736 rs3781619 chr11:47255317 C/T cg25783544 chr11:47291846 MADD 0.47 5.98 0.31 5.6e-9 Proinsulin levels; LIHC trans rs208520 1.000 rs208535 chr6:66962286 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.69 -0.34 9.29e-11 Exhaled nitric oxide output; LIHC cis rs6570726 0.791 rs12208812 chr6:145900924 T/G cg23711669 chr6:146136114 FBXO30 0.74 12.78 0.57 7.66e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg11952622 chr19:58962976 ZNF324B 0.47 7.12 0.36 6.31e-12 Uric acid clearance; LIHC cis rs10540 1.000 rs12794284 chr11:477623 C/T cg03352830 chr11:487213 PTDSS2 0.68 5.86 0.3 1.1e-8 Body mass index; LIHC cis rs999943 0.846 rs9366826 chr6:33619184 C/G cg14003231 chr6:33640908 ITPR3 0.36 7.64 0.38 2.26e-13 Obesity (extreme); LIHC trans rs1814175 0.616 rs847641 chr11:49919261 T/C cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs4668356 0.773 rs60091560 chr2:172031406 T/C cg13882835 chr2:172017928 TLK1 0.45 6.01 0.31 4.76e-9 Cognitive performance; LIHC cis rs7772486 0.754 rs9386134 chr6:146145508 G/A cg05347473 chr6:146136440 FBXO30 0.42 6.68 0.34 9.55e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs763121 0.853 rs5750672 chr22:39104168 C/T cg14440974 chr22:39074834 NA 0.44 7.04 0.36 1.06e-11 Menopause (age at onset); LIHC cis rs7909074 1.000 rs12777258 chr10:45394961 A/G cg04218760 chr10:45406644 TMEM72 0.24 7.39 0.37 1.17e-12 Mean corpuscular volume; LIHC cis rs2933343 0.729 rs1683816 chr3:128651195 G/T cg25356066 chr3:128598488 ACAD9 -0.53 -7.59 -0.38 3.15e-13 IgG glycosylation; LIHC cis rs6545883 0.965 rs6545872 chr2:61724568 G/A cg14146966 chr2:61757674 XPO1 0.47 8.24 0.41 3.71e-15 Tuberculosis; LIHC trans rs561341 0.769 rs9899093 chr17:30191954 C/G cg20587970 chr11:113659929 NA -0.62 -6.41 -0.33 4.93e-10 Hip circumference adjusted for BMI; LIHC cis rs9649465 0.935 rs7780086 chr7:123378471 C/A cg03229431 chr7:123269106 ASB15 -0.38 -8.16 -0.4 6.39e-15 Migraine; LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg08677398 chr8:58056175 NA 0.39 6.02 0.31 4.39e-9 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg06481639 chr22:41940642 POLR3H -0.71 -7.15 -0.36 5.35e-12 Vitiligo; LIHC cis rs56104184 0.830 rs55966626 chr19:49342396 G/T cg15549821 chr19:49342101 PLEKHA4 -1.22 -10.23 -0.48 1.34e-21 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg12311346 chr5:56204834 C5orf35 -0.5 -6.52 -0.33 2.56e-10 Initial pursuit acceleration; LIHC cis rs10870270 1.000 rs7098014 chr10:133775029 G/A cg26149184 chr10:133730230 NA 0.47 7.48 0.37 6.46e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs11031096 0.711 rs1348309 chr11:4202000 A/T cg18678763 chr11:4115507 RRM1 -0.41 -5.94 -0.31 6.88e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs898097 0.625 rs6502017 chr17:80891135 C/T cg15664640 chr17:80829946 TBCD 0.43 7.26 0.37 2.61e-12 Breast cancer; LIHC cis rs228769 0.543 rs170634 chr17:42175821 C/A cg16434002 chr17:42200994 HDAC5 0.45 5.77 0.3 1.73e-8 Bone mineral density (hip);Bone mineral density (spine); LIHC cis rs9733 0.519 rs6700022 chr1:150670484 G/T cg18016565 chr1:150552671 MCL1 -0.57 -11.25 -0.52 3.45e-25 Tonsillectomy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20786246 chr2:72377174 NA 0.42 6.48 0.33 3.29e-10 Cognitive function; LIHC cis rs4820294 0.669 rs1894532 chr22:38059750 T/C cg00142150 chr22:38071001 LGALS1 0.43 7.14 0.36 5.52e-12 Fat distribution (HIV); LIHC cis rs12926788 0.640 rs12924246 chr16:24844629 A/G cg00152838 chr16:24741724 TNRC6A -0.5 -6.19 -0.32 1.73e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9359856 0.564 rs56084221 chr6:90365349 T/C cg13799429 chr6:90582589 CASP8AP2 -0.66 -6.24 -0.32 1.28e-9 Bipolar disorder; LIHC cis rs763121 0.853 rs8140617 chr22:38970439 A/G cg14440974 chr22:39074834 NA 0.39 6.05 0.31 3.86e-9 Menopause (age at onset); LIHC cis rs10779751 0.881 rs2744820 chr1:11365015 G/A cg08854313 chr1:11322531 MTOR -0.77 -12.77 -0.57 8.69e-31 Body mass index; LIHC cis rs8062405 0.721 rs151181 chr16:28490517 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.27 0.32 1.06e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9420 0.807 rs12807357 chr11:57656902 C/T cg19752551 chr11:57585705 CTNND1 -0.46 -6.42 -0.33 4.45e-10 Schizophrenia; LIHC cis rs9388451 0.874 rs9398787 chr6:126090608 A/G cg05901451 chr6:126070800 HEY2 -0.76 -17.95 -0.7 3.19e-51 Brugada syndrome; LIHC cis rs2522056 1.000 rs6874639 chr5:131778716 C/T cg24060327 chr5:131705240 SLC22A5 -0.6 -8.35 -0.41 1.68e-15 Lymphocyte counts;Fibrinogen; LIHC cis rs6723226 0.721 rs10172510 chr2:32620888 A/G cg02381751 chr2:32503542 YIPF4 0.56 8.6 0.42 2.92e-16 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg13395646 chr4:1353034 KIAA1530 -0.61 -8.73 -0.43 1.16e-16 Obesity-related traits; LIHC cis rs10493773 1.000 rs10493773 chr1:86125753 C/T cg17807903 chr1:86174739 ZNHIT6 0.5 7.69 0.38 1.5700000000000001e-13 Urate levels in overweight individuals; LIHC cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg07424592 chr7:64974309 NA 0.79 9.11 0.44 7.25e-18 Diabetic kidney disease; LIHC cis rs7572733 0.515 rs13382697 chr2:198920560 A/C cg00792783 chr2:198669748 PLCL1 0.41 5.97 0.31 5.97e-9 Dermatomyositis; LIHC cis rs765787 0.530 rs28524974 chr15:45543528 C/T cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.79 -0.3 1.61e-8 Uric acid levels; LIHC trans rs7618501 1.000 rs7618501 chr3:49772647 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC cis rs11190604 1.000 rs10883511 chr10:102299407 A/G cg07080220 chr10:102295463 HIF1AN 0.54 7.91 0.39 3.72e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs77861329 1.000 rs72964044 chr3:52092670 G/C cg08692210 chr3:52188851 WDR51A 0.85 7.73 0.39 1.22e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs6062302 0.522 rs3761126 chr20:62252044 C/T cg06363034 chr20:62225388 GMEB2 -0.45 -7.63 -0.38 2.4e-13 Glioblastoma; LIHC cis rs6089584 0.962 rs6142913 chr20:60566950 A/G cg23262073 chr20:60523788 NA -0.28 -5.89 -0.3 9.17e-9 Body mass index; LIHC cis rs459571 0.959 rs461462 chr9:136911272 C/T cg13789015 chr9:136890014 NCRNA00094 0.42 7.74 0.39 1.16e-13 Platelet distribution width; LIHC trans rs2235573 0.551 rs139892 chr22:38388203 C/T cg19894588 chr14:64061835 NA 0.46 6.14 0.32 2.34e-9 Glioblastoma;Glioma; LIHC cis rs2760061 0.626 rs672907 chr1:228120345 G/A cg01200585 chr1:228362443 C1orf69 -0.39 -5.85 -0.3 1.17e-8 Diastolic blood pressure; LIHC cis rs3020736 0.500 rs6002601 chr22:42489058 A/T cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs9640161 0.673 rs11773351 chr7:150030963 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.54 -8.87 -0.43 4.15e-17 Blood protein levels;Circulating chemerin levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21937244 chr14:103406412 CDC42BPB 0.45 7.16 0.36 5e-12 Cognitive function; LIHC cis rs921968 0.545 rs2433738 chr2:219551036 T/A cg02985541 chr2:219472218 PLCD4 -0.39 -6.48 -0.33 3.18e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs4332037 0.906 rs62442903 chr7:1953416 G/A cg23422044 chr7:1970798 MAD1L1 -0.59 -6.75 -0.34 6.32e-11 Bipolar disorder; LIHC cis rs354225 0.546 rs10170646 chr2:54799606 T/C cg26097391 chr2:54893211 SPTBN1 0.44 6.48 0.33 3.18e-10 Schizophrenia; LIHC cis rs918629 0.798 rs2161318 chr5:95288576 C/T cg10483112 chr5:95245456 ELL2 0.37 6.5 0.33 2.81e-10 IgG glycosylation; LIHC cis rs1003719 0.680 rs2835664 chr21:38573429 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs6088580 0.634 rs3746455 chr20:32957216 G/A cg08999081 chr20:33150536 PIGU -0.66 -13.2 -0.58 1.87e-32 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg02290350 chr8:58132656 NA 0.47 9.55 0.46 2.57e-19 Developmental language disorder (linguistic errors); LIHC cis rs6860806 0.531 rs270607 chr5:131649186 A/G cg24060327 chr5:131705240 SLC22A5 -0.8 -12.28 -0.55 5.94e-29 Breast cancer; LIHC cis rs4713118 0.662 rs149948 chr6:27974817 C/G cg16479474 chr6:28041457 NA 0.44 6.67 0.34 1.03e-10 Parkinson's disease; LIHC cis rs8067545 0.636 rs11204300 chr17:20195438 C/T cg13482628 chr17:19912719 NA -0.41 -6.77 -0.34 5.62e-11 Schizophrenia; LIHC cis rs172166 0.611 rs203882 chr6:28078502 G/A cg23485639 chr6:28045615 ZNF165 0.4 6.3 0.32 9.03e-10 Cardiac Troponin-T levels; LIHC cis rs11608355 0.515 rs2241204 chr12:109972037 G/A cg05360138 chr12:110035743 NA 0.91 10.32 0.49 6.65e-22 Neuroticism; LIHC cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.55 8.71 0.43 1.34e-16 Schizophrenia; LIHC cis rs4423214 0.610 rs3763856 chr11:71125345 G/A cg05163923 chr11:71159392 DHCR7 0.76 11.64 0.53 1.36e-26 Vitamin D levels; LIHC cis rs1790761 0.692 rs611663 chr11:67312221 C/T cg21734168 chr11:67353974 GSTP1 -0.27 -6.57 -0.33 1.92e-10 Mean corpuscular volume; LIHC cis rs9902453 0.765 rs2628167 chr17:28064498 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.36 -0.59 4.92e-33 Coffee consumption (cups per day); LIHC trans rs116095464 0.558 rs7714335 chr5:263513 T/C cg00938859 chr5:1591904 SDHAP3 0.61 7.32 0.37 1.75e-12 Breast cancer; LIHC cis rs11690935 0.959 rs7572215 chr2:172634228 G/A cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.71 -0.69 2.95e-50 Schizophrenia; LIHC cis rs7584330 0.554 rs9646716 chr2:238443784 C/T cg08992911 chr2:238395768 MLPH 0.5 6.01 0.31 4.86e-9 Prostate cancer; LIHC cis rs919433 0.647 rs2045242 chr2:198507649 G/A cg03934865 chr2:198174659 NA 0.46 6.81 0.35 4.35e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7208859 0.623 rs9900144 chr17:29208389 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs12477438 0.605 rs4585080 chr2:99557327 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.56 -7.66 -0.38 1.91e-13 Chronic sinus infection; LIHC cis rs7534824 0.507 rs7518380 chr1:101451262 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 7.91 0.39 3.59e-14 Refractive astigmatism; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg19569686 chr19:1555141 MEX3D 0.4 6.08 0.31 3.21e-9 Bilirubin levels; LIHC trans rs783540 0.934 rs36109438 chr15:83264459 T/G cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.66 -0.34 1.09e-10 Schizophrenia; LIHC cis rs1707322 0.682 rs28508523 chr1:46189625 G/A cg03146154 chr1:46216737 IPP 0.59 10.17 0.48 2.07e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2066819 1.000 rs77768890 chr12:56725121 A/G cg26734620 chr12:56694298 CS 1.29 11.3 0.52 2.28e-25 Psoriasis vulgaris; LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg25894440 chr7:65020034 NA 0.4 6.32 0.32 8.19e-10 Calcium levels; LIHC cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg08219700 chr8:58056026 NA 0.46 5.78 0.3 1.71e-8 Developmental language disorder (linguistic errors); LIHC cis rs798766 1.000 rs798766 chr4:1734239 C/T cg21231739 chr4:1642635 FAM53A 0.37 6.16 0.32 2.08e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs17102423 0.859 rs34184001 chr14:65596027 T/C cg11161011 chr14:65562177 MAX -0.41 -5.97 -0.31 5.95e-9 Obesity-related traits; LIHC cis rs6860806 0.531 rs2631359 chr5:131707892 C/T cg24060327 chr5:131705240 SLC22A5 0.79 12.43 0.56 1.53e-29 Breast cancer; LIHC cis rs9399135 0.967 rs9389258 chr6:135361140 T/C cg22676075 chr6:135203613 NA 0.42 6.65 0.34 1.15e-10 Red blood cell count; LIHC cis rs5753618 0.509 rs5749224 chr22:31558549 C/T cg07713946 chr22:31675144 LIMK2 -0.43 -7.72 -0.39 1.25e-13 Colorectal cancer; LIHC cis rs116095464 0.558 rs7713524 chr5:276200 C/T cg22857025 chr5:266934 NA 1.37 18.17 0.7 3.95e-52 Breast cancer; LIHC cis rs7106204 0.702 rs11826172 chr11:24233998 G/A ch.11.24196551F chr11:24239977 NA 0.78 11.03 0.51 2.18e-24 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4450131 0.902 rs10794174 chr10:126357981 T/C cg20435097 chr10:126320824 FAM53B -0.49 -8.99 -0.44 1.68e-17 White blood cell count (basophil); LIHC cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg10360323 chr17:41437877 NA 0.39 5.71 0.3 2.44e-8 Menopause (age at onset); LIHC cis rs8017423 0.647 rs4904674 chr14:90817412 G/A cg04374321 chr14:90722782 PSMC1 -0.5 -7.25 -0.36 2.83e-12 Mortality in heart failure; LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg20607798 chr8:58055168 NA 0.62 7.92 0.39 3.38e-14 Developmental language disorder (linguistic errors); LIHC cis rs7520050 0.931 rs11576305 chr1:46460046 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 6.02 0.31 4.5e-9 Red blood cell count;Reticulocyte count; LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg11965913 chr1:205819406 PM20D1 0.76 11.34 0.52 1.65e-25 Menarche (age at onset); LIHC cis rs11792861 0.589 rs75742991 chr9:111929624 C/G cg05043794 chr9:111880884 C9orf5 -0.27 -5.9 -0.3 8.73e-9 Menarche (age at onset); LIHC cis rs1401999 1.000 rs7620350 chr3:183710053 A/T cg05044414 chr3:183734942 ABCC5 0.34 6.02 0.31 4.46e-9 Anterior chamber depth; LIHC cis rs7919006 1.000 rs2395127 chr10:76772778 A/T cg01390419 chr10:76803856 DUPD1 0.44 6.84 0.35 3.59e-11 Weight; LIHC cis rs986417 1.000 rs1254296 chr14:60870389 T/C cg27398547 chr14:60952738 C14orf39 -0.71 -8.02 -0.4 1.74e-14 Gut microbiota (bacterial taxa); LIHC trans rs1814175 0.791 rs11040472 chr11:49703116 C/T cg15704280 chr7:45808275 SEPT13 -1.04 -23.92 -0.79 5.38e-75 Height; LIHC cis rs12765878 0.934 rs11191841 chr10:105639611 C/T cg11005552 chr10:105648138 OBFC1 -0.38 -5.96 -0.31 6.19e-9 Coronary artery disease; LIHC cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg11764359 chr7:65958608 NA 0.56 5.96 0.31 6.14e-9 Diabetic kidney disease; LIHC cis rs7927592 0.731 rs488381 chr11:68291693 G/A cg20283391 chr11:68216788 NA 0.36 5.73 0.3 2.16e-8 Total body bone mineral density; LIHC cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg18404041 chr3:52824283 ITIH1 0.58 9.37 0.45 1.03e-18 Bipolar disorder; LIHC cis rs10420951 0.542 rs2303693 chr19:18557673 A/G cg10790698 chr19:18539756 SSBP4 0.43 6.06 0.31 3.58e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67460515 0.892 rs35310734 chr3:160943209 T/G cg03342759 chr3:160939853 NMD3 -0.67 -10.1 -0.48 3.57e-21 Parkinson's disease; LIHC cis rs921968 0.541 rs514356 chr2:219375018 C/T cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs13161895 0.877 rs75654641 chr5:179486021 C/T cg06664874 chr5:179499304 RNF130 0.67 7.72 0.39 1.3e-13 LDL cholesterol; LIHC cis rs9326248 1.000 rs7107152 chr11:117056080 C/T cg15534755 chr11:117069859 TAGLN -0.37 -6.25 -0.32 1.25e-9 Blood protein levels; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg02592271 chr2:27665507 KRTCAP3 -0.46 -6.41 -0.33 4.78e-10 Total body bone mineral density; LIHC cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.16 -0.36 5.11e-12 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg05590025 chr7:65112418 INTS4L2 -0.63 -6.87 -0.35 3e-11 Diabetic kidney disease; LIHC trans rs9747201 0.962 rs35051180 chr17:80135046 G/A cg07393940 chr7:158741817 NA -0.57 -6.76 -0.34 5.84e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg06453172 chr10:134556979 INPP5A -0.62 -7.77 -0.39 9.51e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg13770153 chr20:60521292 NA -0.36 -7.2 -0.36 3.88e-12 Body mass index; LIHC cis rs1008375 1.000 rs1974624 chr4:17650281 A/G cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.64e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11871801 0.750 rs7216927 chr17:40651497 T/A cg14558262 chr17:40713999 COASY 0.49 6.83 0.35 3.88e-11 Crohn's disease; LIHC cis rs6754311 0.773 rs666407 chr2:136640233 A/G cg17750252 chr2:136567154 LCT -0.34 -6.13 -0.31 2.47e-9 Mosquito bite size; LIHC cis rs73001065 0.901 rs73004962 chr19:19713069 A/T cg03709012 chr19:19516395 GATAD2A 0.86 7.93 0.39 3.16e-14 LDL cholesterol; LIHC cis rs34779708 0.733 rs7081597 chr10:35546331 G/C cg03585969 chr10:35415529 CREM 0.75 10.83 0.51 1.04e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs910316 0.967 rs4899549 chr14:75647494 G/A cg11812906 chr14:75593930 NEK9 -0.73 -13.8 -0.6 9.43e-35 Height; LIHC cis rs12497850 0.931 rs9311432 chr3:48850443 T/A cg06212747 chr3:49208901 KLHDC8B 0.55 7.12 0.36 6.57e-12 Parkinson's disease; LIHC cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg12379764 chr21:47803548 PCNT -0.57 -8.6 -0.42 2.95e-16 Testicular germ cell tumor; LIHC cis rs12431939 0.947 rs56156789 chr14:51633899 C/G cg23942311 chr14:51606299 NA -0.36 -5.87 -0.3 1.02e-8 Cancer; LIHC cis rs4974559 1.000 rs4974559 chr4:1380848 C/T cg02980000 chr4:1222292 CTBP1 -0.52 -7.05 -0.36 9.95e-12 Systolic blood pressure; LIHC cis rs7927771 0.839 rs3817334 chr11:47650993 C/T cg20135002 chr11:47629003 NA -0.5 -8.67 -0.42 1.78e-16 Subjective well-being; LIHC cis rs600806 0.778 rs11101961 chr1:110008813 T/C cg23091122 chr1:110024289 SYPL2 -0.47 -6.36 -0.33 6.47e-10 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs2327053 chr6:8443127 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.63 0.53 1.38e-26 Motion sickness; LIHC cis rs10751667 0.666 rs10902248 chr11:957742 A/G cg06064525 chr11:970664 AP2A2 -0.56 -15.03 -0.63 1.52e-39 Alzheimer's disease (late onset); LIHC cis rs10791097 0.694 rs7125622 chr11:130743388 T/C cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9916302 0.904 rs4795357 chr17:37569551 T/C cg00129232 chr17:37814104 STARD3 -0.41 -6.49 -0.33 2.95e-10 Glomerular filtration rate (creatinine); LIHC cis rs4803468 0.967 rs3213860 chr19:41920211 T/C cg09537434 chr19:41945824 ATP5SL -1.04 -22.17 -0.77 3.79e-68 Height; LIHC cis rs807029 0.533 rs3740485 chr10:102750621 C/T cg27255678 chr10:102756921 LZTS2 0.51 7.31 0.37 1.89e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2273669 0.667 rs4527738 chr6:109309150 T/C cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs10791323 0.569 rs11223609 chr11:133741766 C/T cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.53e-9 Childhood ear infection; LIHC cis rs116095464 0.558 rs13357299 chr5:242211 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.7 -0.5 3.15e-23 Breast cancer; LIHC cis rs10744422 0.925 rs2292132 chr12:123332834 T/C cg07706471 chr12:123319906 HIP1R -0.62 -8.23 -0.41 4.12e-15 Schizophrenia; LIHC cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg11062466 chr8:58055876 NA 0.48 6.63 0.34 1.28e-10 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.553 rs2984099 chr6:8637274 C/T cg07606381 chr6:8435919 SLC35B3 -0.81 -11.84 -0.54 2.39e-27 Motion sickness; LIHC cis rs1030268 0.651 rs12707118 chr7:133474900 C/T cg03336402 chr7:133662267 EXOC4 0.47 6.08 0.31 3.21e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs2439831 0.618 rs8023508 chr15:44176103 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.53 -6.65 -0.34 1.15e-10 Lung cancer in ever smokers; LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg16070018 chr6:26224392 HIST1H3E 0.59 7.45 0.37 7.55e-13 Gout;Renal underexcretion gout; LIHC cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg00684032 chr4:1343700 KIAA1530 0.36 5.9 0.3 8.67e-9 Obesity-related traits; LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs74544699 1.000 rs7666671 chr4:74807007 G/A cg16072462 chr4:74847758 PF4 0.59 6.02 0.31 4.45e-9 Growth-regulated protein alpha levels; LIHC cis rs2072499 1.000 rs2072499 chr1:156169610 A/G cg25208724 chr1:156163844 SLC25A44 0.93 15.89 0.65 5.65e-43 Testicular germ cell tumor; LIHC cis rs12477438 0.748 rs10200974 chr2:99675227 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs1865721 1.000 rs72977879 chr18:73193696 T/C cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.17e-13 Intelligence; LIHC cis rs9534288 0.797 rs7989351 chr13:46534080 C/A cg15192986 chr13:46630673 CPB2 -0.54 -8.39 -0.41 1.29e-15 Blood protein levels; LIHC cis rs611744 0.870 rs685358 chr8:109161413 T/C cg18478394 chr8:109455254 TTC35 0.39 6.66 0.34 1.1e-10 Dupuytren's disease; LIHC cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg15691649 chr6:25882328 NA 0.5 7.23 0.36 3.17e-12 Blood metabolite levels; LIHC cis rs6450176 1.000 rs3776716 chr5:53298923 A/G ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1949733 1.000 rs2631745 chr4:8490530 T/C cg11789530 chr4:8429930 ACOX3 -0.81 -11.91 -0.54 1.39e-27 Response to antineoplastic agents; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.54 -7.64 -0.38 2.17e-13 Lymphocyte counts; LIHC cis rs12497850 0.864 rs6779394 chr3:49157771 G/A cg06212747 chr3:49208901 KLHDC8B 0.59 7.55 0.38 3.96e-13 Parkinson's disease; LIHC cis rs7258465 1.000 rs271621 chr19:18631332 C/A cg01065977 chr19:18549689 ISYNA1 -0.38 -5.98 -0.31 5.67e-9 Breast cancer; LIHC cis rs763014 0.932 rs2384972 chr16:674424 G/A cg00908189 chr16:619842 PIGQ 0.83 13.13 0.58 3.52e-32 Height; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs8072100 0.840 rs9900360 chr17:45491979 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.36 -5.83 -0.3 1.3e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs11603020 0.950 rs28362947 chr11:57369008 C/G cg19752551 chr11:57585705 CTNND1 -0.54 -6.73 -0.34 7.15e-11 Blood protein levels; LIHC cis rs782590 0.902 rs782602 chr2:55849309 A/G cg03859395 chr2:55845619 SMEK2 0.89 15.32 0.64 1.04e-40 Metabolic syndrome; LIHC cis rs2243480 1.000 rs2243480 chr7:65599196 C/T cg18252515 chr7:66147081 NA -1.26 -15.71 -0.65 2.88e-42 Diabetic kidney disease; LIHC cis rs2806561 0.929 rs627304 chr1:23537555 A/G cg19743168 chr1:23544995 NA 0.4 7.41 0.37 9.69e-13 Height; LIHC cis rs11148252 0.774 rs7334583 chr13:52930352 G/T cg00495681 chr13:53174319 NA -0.41 -6.67 -0.34 1.02e-10 Lewy body disease; LIHC cis rs4728302 0.869 rs13231079 chr7:133604373 C/G cg10665199 chr7:133106180 EXOC4 0.39 6.81 0.35 4.51e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs9486715 1.000 rs7752277 chr6:97065131 C/T cg06623918 chr6:96969491 KIAA0776 -0.83 -13.65 -0.59 3.51e-34 Headache; LIHC cis rs6582630 0.555 rs1906260 chr12:38601013 T/G cg26384229 chr12:38710491 ALG10B 0.98 12.83 0.57 4.89e-31 Drug-induced liver injury (flucloxacillin); LIHC cis rs6963495 0.745 rs75805443 chr7:105162828 A/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs4319547 0.697 rs7974262 chr12:122896385 C/T cg23029597 chr12:123009494 RSRC2 0.52 7.34 0.37 1.54e-12 Body mass index; LIHC cis rs6938 0.618 rs11633472 chr15:75184084 T/G cg14664628 chr15:75095509 CSK -0.46 -5.74 -0.3 2.05e-8 Breast cancer; LIHC cis rs1707322 1.000 rs11211204 chr1:46317864 A/G cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg00149659 chr3:10157352 C3orf10 0.6 6.62 0.34 1.36e-10 Alzheimer's disease; LIHC cis rs2153535 0.580 rs1335641 chr6:8487860 G/T cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg06951627 chr6:26196580 NA 0.55 6.43 0.33 4.39e-10 Gout;Renal underexcretion gout; LIHC cis rs17685 0.753 rs11972240 chr7:75694079 A/C cg04592579 chr7:75616294 TMEM120A 0.41 6.98 0.35 1.52e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4742903 0.935 rs4742907 chr9:106968226 G/A cg14250997 chr9:106856677 SMC2 0.35 5.87 0.3 1.04e-8 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs9914988 0.943 rs9913801 chr17:27132105 G/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.86 -0.35 3.23e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6061231 0.518 rs639836 chr20:60926223 G/A cg03945807 chr20:60948434 NA -0.38 -6.9 -0.35 2.5e-11 Colorectal cancer; LIHC cis rs546131 0.571 rs11601422 chr11:34793759 G/A cg11058730 chr11:34937778 PDHX;APIP -0.51 -6.23 -0.32 1.4e-9 Lung disease severity in cystic fibrosis; LIHC cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg06238570 chr21:40685208 BRWD1 0.62 7.52 0.38 4.77e-13 Cognitive function; LIHC cis rs2153535 0.580 rs1319169 chr6:8464456 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs1878931 0.531 rs9635548 chr16:3417156 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.71 10.67 0.5 3.76e-23 Body mass index (adult); LIHC cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg07424592 chr7:64974309 NA 0.8 9.15 0.44 5.17e-18 Diabetic kidney disease; LIHC cis rs4819052 0.851 rs914214 chr21:46697820 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 11.83 0.54 2.59e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs556990 0.574 rs473598 chr13:113801189 C/T cg18105134 chr13:113819100 PROZ -0.42 -6.76 -0.34 6.13e-11 Blood protein levels; LIHC cis rs798554 0.757 rs1182176 chr7:2874601 A/G cg19346786 chr7:2764209 NA -0.45 -6.41 -0.33 4.95e-10 Height; LIHC cis rs6500602 0.647 rs1641868 chr16:4594503 G/C cg08645402 chr16:4508243 NA 0.37 6.82 0.35 4.12e-11 Schizophrenia; LIHC trans rs6717918 0.517 rs2853362 chr2:233122412 A/G cg19760917 chr1:2411643 PLCH2 -0.41 -6.41 -0.33 4.69e-10 Height; LIHC trans rs208520 1.000 rs72884017 chr6:66992513 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 7.14 0.36 5.52e-12 Exhaled nitric oxide output; LIHC cis rs7122539 0.646 rs608248 chr11:66562248 C/T cg04006266 chr11:66300458 BBS1 -0.33 -5.75 -0.3 2e-8 HIV-1 susceptibility; LIHC cis rs734999 0.611 rs10797431 chr1:2501222 G/T cg18854424 chr1:2615690 NA 0.33 7.18 0.36 4.26e-12 Ulcerative colitis; LIHC cis rs858239 0.570 rs10235467 chr7:23148808 C/T cg23682824 chr7:23144976 KLHL7 0.44 6.68 0.34 9.75e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs17135159 0.625 rs11251873 chr10:3436109 A/G cg20417998 chr20:34252789 CPNE1;RBM12 -0.5 -6.11 -0.31 2.7e-9 Reading and spelling; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.29 0.52 2.46e-25 Prudent dietary pattern; LIHC cis rs9560113 1.000 rs914026 chr13:112182029 G/A cg14154082 chr13:112174009 NA 0.3 6.26 0.32 1.16e-9 Menarche (age at onset); LIHC cis rs7208859 0.623 rs1061346 chr17:29114229 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10751667 0.600 rs6597948 chr11:1005308 C/T cg06064525 chr11:970664 AP2A2 -0.44 -10.55 -0.5 9.97e-23 Alzheimer's disease (late onset); LIHC cis rs1707322 0.928 rs6681068 chr1:46398382 G/A cg03146154 chr1:46216737 IPP 0.47 7.65 0.38 2.12e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8017423 1.000 rs4900028 chr14:90685594 C/T cg14092571 chr14:90743983 NA -0.37 -5.89 -0.3 9.22e-9 Mortality in heart failure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06625838 chr5:162865006 CCNG1 0.45 6.18 0.32 1.81e-9 Pancreatic cancer; LIHC cis rs870825 0.860 rs62339895 chr4:185598681 A/G cg04058563 chr4:185651563 MLF1IP -0.7 -6.39 -0.33 5.43e-10 Blood protein levels; LIHC cis rs4727027 0.635 rs12111923 chr7:148885877 G/A cg23583168 chr7:148888333 NA -0.76 -9.68 -0.46 9.89e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs3780486 1.000 rs10813957 chr9:33153527 G/T cg20290983 chr6:43655470 MRPS18A 1.08 20.28 0.74 1.34e-60 IgG glycosylation; LIHC cis rs4319547 0.774 rs7959238 chr12:123131498 A/T cg05707623 chr12:122985044 ZCCHC8 -0.5 -6.79 -0.34 4.85e-11 Body mass index; LIHC cis rs748404 0.650 rs518261 chr15:43573429 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.02 0.35 1.21e-11 Lung cancer; LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg00800038 chr16:89945340 TCF25 -0.69 -10.96 -0.51 3.81e-24 Skin colour saturation; LIHC cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg03452623 chr4:187889614 NA -0.35 -9.19 -0.44 4e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 1.000 rs444988 chr6:167389674 A/T cg23791538 chr6:167370224 RNASET2 -0.59 -9.37 -0.45 1.02e-18 Crohn's disease; LIHC cis rs875971 1.000 rs55962648 chr7:65625751 C/G cg11764359 chr7:65958608 NA -0.88 -15.37 -0.64 6.43e-41 Aortic root size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02424695 chr17:17399795 RASD1 0.45 6.6 0.34 1.61e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs561341 1.000 rs72823785 chr17:30273784 C/T cg20587970 chr11:113659929 NA -1.46 -11.85 -0.54 2.34e-27 Hip circumference adjusted for BMI; LIHC trans rs3785309 0.519 rs7197253 chr16:276549 C/T cg04806177 chr16:1991447 SEPX1 0.42 6.08 0.31 3.2e-9 Immature fraction of reticulocytes; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg15160873 chr2:128471243 WDR33 0.41 6.4 0.33 5.12e-10 Immature fraction of reticulocytes; LIHC cis rs7666738 0.830 rs7659420 chr4:98878714 G/C cg05340658 chr4:99064831 C4orf37 0.67 12.29 0.55 5.33e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg12016809 chr21:47604291 C21orf56 0.4 5.85 0.3 1.16e-8 Testicular germ cell tumor; LIHC cis rs1008375 1.000 rs3846357 chr4:17635887 A/T cg02297831 chr4:17616191 MED28 0.5 7.9 0.39 3.86e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10744422 0.925 rs2880678 chr12:123317099 C/T cg22842854 chr12:123319900 HIP1R -0.65 -8.39 -0.41 1.28e-15 Schizophrenia; LIHC cis rs903552 0.736 rs9806495 chr15:102008059 G/A cg19295451 chr15:102010161 PCSK6 -0.55 -7.7 -0.38 1.53e-13 Diabetic kidney disease; LIHC cis rs9630089 0.622 rs4919083 chr10:98958738 T/C cg25902810 chr10:99078978 FRAT1 0.42 5.86 0.3 1.1e-8 Neutrophil percentage of white cells; LIHC cis rs4319547 0.695 rs4758643 chr12:122924819 A/T cg23029597 chr12:123009494 RSRC2 -0.52 -7.32 -0.37 1.73e-12 Body mass index; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.51e-13 Prudent dietary pattern; LIHC cis rs9560113 1.000 rs4773384 chr13:112177987 A/G cg14154082 chr13:112174009 NA 0.29 6.14 0.32 2.28e-9 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10139015 chr11:47448256 PSMC3 0.37 6.1 0.31 2.91e-9 Pancreatic cancer; LIHC cis rs367615 0.731 rs58241713 chr5:108853664 G/A cg17395555 chr5:108820864 NA 0.38 8.12 0.4 8.58e-15 Colorectal cancer (SNP x SNP interaction); LIHC cis rs2839186 0.681 rs13047198 chr21:47701835 T/C cg00612595 chr21:47717864 NA -0.39 -6.34 -0.32 7.47e-10 Testicular germ cell tumor; LIHC cis rs12791968 1.000 rs1552301 chr11:45002551 A/G cg11846598 chr11:44996168 LOC221122 -0.44 -7.89 -0.39 4.26e-14 Inhibitory control; LIHC cis rs7615952 0.866 rs1976459 chr3:125647486 A/T cg05084668 chr3:125655381 ALG1L -0.6 -8.59 -0.42 3.09e-16 Blood pressure (smoking interaction); LIHC cis rs6500602 0.702 rs11645519 chr16:4538989 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.49 7.58 0.38 3.2e-13 Schizophrenia; LIHC cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs4908768 0.906 rs6678982 chr1:8577185 C/A cg20416874 chr1:8611966 RERE 0.58 9.11 0.44 6.9e-18 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs17685 0.712 rs869805 chr7:75688596 C/T cg04610667 chr7:75704037 NA -0.35 -6.25 -0.32 1.23e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs5753618 0.561 rs4820963 chr22:31698166 C/T cg07713946 chr22:31675144 LIMK2 -0.43 -7.8 -0.39 7.68e-14 Colorectal cancer; LIHC cis rs9399135 0.816 rs4134030 chr6:135354094 G/T cg22676075 chr6:135203613 NA 0.4 6.55 0.33 2.13e-10 Red blood cell count; LIHC cis rs7659604 0.676 rs6855269 chr4:122697418 T/G cg19748678 chr4:122722346 EXOSC9 0.65 10.67 0.5 3.83e-23 Type 2 diabetes; LIHC cis rs769267 0.598 rs8108705 chr19:19675367 G/T cg03709012 chr19:19516395 GATAD2A -0.86 -12.44 -0.56 1.4e-29 Tonsillectomy; LIHC cis rs875971 0.660 rs3764903 chr7:66098482 G/A cg18876405 chr7:65276391 NA -0.45 -7.88 -0.39 4.48e-14 Aortic root size; LIHC cis rs2153535 0.580 rs1928184 chr6:8532108 T/A cg21535247 chr6:8435926 SLC35B3 0.66 8.73 0.43 1.16e-16 Motion sickness; LIHC cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg11764359 chr7:65958608 NA 0.57 6.0 0.31 4.9e-9 Diabetic kidney disease; LIHC cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.15e-51 Menopause (age at onset); LIHC cis rs9733 0.596 rs6661872 chr1:150628357 C/G cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs8062405 1.000 rs7205323 chr16:28865892 C/T cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4665809 1.000 rs4665308 chr2:26330514 C/A cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs9457247 0.602 rs10484530 chr6:167461562 C/T cg23791538 chr6:167370224 RNASET2 -0.51 -7.79 -0.39 7.91e-14 Crohn's disease; LIHC cis rs1163251 0.902 rs627707 chr1:120217133 C/G cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC trans rs2243480 1.000 rs35421653 chr7:65363429 C/A cg10756647 chr7:56101905 PSPH 1.11 13.23 0.58 1.43e-32 Diabetic kidney disease; LIHC cis rs3806843 0.706 rs1089305 chr5:140066306 T/C cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20091523 chr11:58909996 FAM111A 0.44 6.57 0.33 1.89e-10 Calcium levels; LIHC cis rs12477438 0.520 rs11689265 chr2:99799267 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.24 24.53 0.8 2.3e-77 Chronic sinus infection; LIHC cis rs6684514 1.000 rs10752615 chr1:156248609 T/C cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7208859 0.623 rs216446 chr17:28933718 T/G cg14067834 chr17:29058358 SUZ12P 0.66 6.64 0.34 1.26e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9549260 0.755 rs9549236 chr13:41147158 C/T cg21288729 chr13:41239152 FOXO1 -0.59 -10.02 -0.48 6.64e-21 Red blood cell count; LIHC cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg14222432 chr12:29376421 FAR2 0.38 7.19 0.36 4.1e-12 QT interval; LIHC cis rs4700695 0.686 rs27075 chr5:65370379 C/T cg21114390 chr5:65439923 SFRS12 -0.47 -6.04 -0.31 3.91e-9 Facial morphology (factor 19); LIHC cis rs7044106 0.690 rs10739569 chr9:123361027 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.48 0.38 6.29e-13 Hip circumference adjusted for BMI; LIHC cis rs4006360 0.646 rs8080164 chr17:39292845 A/G cg20663846 chr17:39254439 KRTAP4-8 0.2 5.77 0.3 1.78e-8 Bipolar disorder and schizophrenia; LIHC cis rs1005277 0.577 rs4934906 chr10:38015028 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.67 -0.46 1.04e-19 Extrinsic epigenetic age acceleration; LIHC cis rs10078 0.515 rs890984 chr5:479540 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.73 9.72 0.47 7.02e-20 Fat distribution (HIV); LIHC cis rs9303280 0.806 rs11078927 chr17:38064405 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.73 0.3 2.17e-8 Self-reported allergy; LIHC cis rs8027181 0.959 rs11631352 chr15:73086473 A/G cg25632853 chr15:73088954 NA -0.4 -6.66 -0.34 1.07e-10 Triglyceride levels; LIHC cis rs9549367 0.789 rs12866090 chr13:113869410 G/A cg18105134 chr13:113819100 PROZ -0.66 -11.36 -0.52 1.39e-25 Platelet distribution width; LIHC cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -8.98 -0.44 1.87e-17 Bipolar disorder; LIHC cis rs6570726 0.791 rs10872577 chr6:145900560 G/T cg23711669 chr6:146136114 FBXO30 0.71 12.2 0.55 1.19e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs2303759 0.918 rs8107548 chr19:49870643 T/C cg05022225 chr19:49866942 DKKL1;TEAD2 0.56 8.66 0.42 1.92e-16 Multiple sclerosis; LIHC cis rs709400 0.663 rs62007681 chr14:103884651 G/A cg26031613 chr14:104095156 KLC1 0.79 10.32 0.49 6.46e-22 Body mass index; LIHC cis rs11630290 0.575 rs7169210 chr15:64165069 T/C cg12036633 chr15:63758958 NA 0.57 5.79 0.3 1.59e-8 Iris characteristics; LIHC cis rs12744310 0.887 rs12045979 chr1:41809477 A/G cg03387723 chr1:41708464 SCMH1 -0.32 -5.71 -0.3 2.4e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs778371 0.723 rs12105766 chr2:233617647 A/G cg08000102 chr2:233561755 GIGYF2 0.88 14.57 0.62 9.52e-38 Schizophrenia; LIHC cis rs9682041 1.000 rs9682041 chr3:170091902 C/T cg11886554 chr3:170076028 SKIL 0.72 6.21 0.32 1.57e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs9649465 0.967 rs11769381 chr7:123264804 C/T cg03229431 chr7:123269106 ASB15 -0.41 -9.15 -0.44 5.34e-18 Migraine; LIHC cis rs17376456 0.877 rs7736620 chr5:93305762 C/T cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs9443189 0.570 rs485906 chr6:76300550 A/C cg01950844 chr6:76311363 SENP6 0.89 11.02 0.51 2.3e-24 Prostate cancer; LIHC cis rs10791097 0.694 rs7125622 chr11:130743388 T/C cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2112347 0.502 rs34339 chr5:74931333 G/T cg06933384 chr5:74808293 COL4A3BP;POLK -0.45 -6.34 -0.32 7.38e-10 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs5769765 0.837 rs4824110 chr22:50271631 T/A cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs9583531 0.843 rs7999702 chr13:111382264 A/C cg24331049 chr13:111365604 ING1 -0.67 -9.21 -0.45 3.31e-18 Coronary artery disease; LIHC cis rs7296418 0.885 rs1790104 chr12:123709409 C/T cg05973401 chr12:123451056 ABCB9 0.44 6.39 0.33 5.28e-10 Platelet count; LIHC cis rs7089973 0.604 rs2420066 chr10:116583897 A/G cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4407350 1.000 rs9626478 chr22:44923619 A/G cg26276947 chr22:44892394 LDOC1L 0.33 6.08 0.31 3.12e-9 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.557 rs2983338 chr10:38550734 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.08 -0.44 9.06e-18 Extrinsic epigenetic age acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16012478 chr7:98609764 TRRAP 0.39 6.54 0.33 2.29e-10 Longevity; LIHC cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg17554472 chr22:41940697 POLR3H 0.56 6.23 0.32 1.34e-9 Vitiligo; LIHC cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg11062466 chr8:58055876 NA 0.4 5.82 0.3 1.36e-8 Developmental language disorder (linguistic errors); LIHC cis rs1577917 1.000 rs68171315 chr6:86707400 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.63 -0.46 1.43e-19 Response to antipsychotic treatment; LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg11070056 chr1:107600091 PRMT6 0.68 11.54 0.53 3.02e-26 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06320982 chr16:58718767 SLC38A7 0.35 6.3 0.32 9.41e-10 Cognitive function; LIHC cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg02187348 chr16:89574699 SPG7 0.66 10.57 0.5 9.03e-23 Multiple myeloma (IgH translocation); LIHC cis rs12472274 0.646 rs2305171 chr2:239097140 G/A cg17459225 chr2:239074497 NA 0.72 11.23 0.52 4.11e-25 Phospholipid levels (plasma); LIHC cis rs6754311 0.731 rs309134 chr2:136755684 A/G cg25344623 chr2:136566232 LCT 0.35 7.14 0.36 5.72e-12 Mosquito bite size; LIHC cis rs763121 0.962 rs6001193 chr22:39074737 A/G cg14440974 chr22:39074834 NA -0.34 -5.77 -0.3 1.77e-8 Menopause (age at onset); LIHC cis rs3008870 1.000 rs975451 chr1:67480060 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 15.93 0.65 3.95e-43 Lymphocyte percentage of white cells; LIHC trans rs561341 0.602 rs114562703 chr17:30233899 G/T cg20587970 chr11:113659929 NA -0.57 -7.14 -0.36 5.56e-12 Hip circumference adjusted for BMI; LIHC cis rs11098499 0.691 rs9996644 chr4:120238877 G/T cg09307838 chr4:120376055 NA 0.72 11.27 0.52 2.89e-25 Corneal astigmatism; LIHC cis rs12701220 0.553 rs9639882 chr7:1133731 G/A cg16145915 chr7:1198662 ZFAND2A -0.35 -7.01 -0.35 1.31e-11 Bronchopulmonary dysplasia; LIHC cis rs763121 0.853 rs2267393 chr22:39101619 G/C cg21395723 chr22:39101663 GTPBP1 0.4 6.67 0.34 1.04e-10 Menopause (age at onset); LIHC cis rs7635838 0.619 rs347614 chr3:11276399 T/C cg00170343 chr3:11313890 ATG7 0.54 8.32 0.41 2.2e-15 HDL cholesterol; LIHC trans rs1814175 0.817 rs28679516 chr11:50055998 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -23.11 -0.78 7.6e-72 Height; LIHC cis rs3096299 0.754 rs3096296 chr16:89411010 C/A cg08822215 chr16:89438651 ANKRD11 -0.44 -6.82 -0.35 4.18e-11 Multiple myeloma (IgH translocation); LIHC cis rs1707322 0.717 rs3014249 chr1:46079493 A/G cg24296786 chr1:45957014 TESK2 0.41 5.81 0.3 1.43e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12594515 1.000 rs6493175 chr15:45989898 T/C cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs344364 0.529 rs186941 chr16:1930088 T/C cg09830162 chr16:1889614 FAHD1;C16orf73 0.69 9.05 0.44 1.08e-17 Glomerular filtration rate in chronic kidney disease; LIHC cis rs739401 0.595 rs2237903 chr11:2967901 C/T cg25174290 chr11:3078921 CARS 0.55 8.42 0.41 1.03e-15 Longevity; LIHC cis rs4604732 0.536 rs12058821 chr1:247649651 G/T cg02104434 chr1:247694406 LOC148824;OR2C3 0.26 6.11 0.31 2.65e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs7572733 0.515 rs6752458 chr2:198835106 G/T cg10820045 chr2:198174542 NA 0.48 7.31 0.37 1.91e-12 Dermatomyositis; LIHC cis rs17106184 0.892 rs72900903 chr1:51053585 A/G cg07174182 chr1:51127561 FAF1 -0.67 -7.1 -0.36 7.38e-12 Type 2 diabetes; LIHC cis rs7959452 0.535 rs4761228 chr12:69682327 G/A cg22834771 chr12:69754056 YEATS4 -0.48 -8.18 -0.4 5.53e-15 Blood protein levels; LIHC cis rs9534288 0.797 rs2182483 chr13:46582600 C/T cg15192986 chr13:46630673 CPB2 -0.54 -8.28 -0.41 2.73e-15 Blood protein levels; LIHC cis rs2933343 0.553 rs789212 chr3:128686912 A/C cg25356066 chr3:128598488 ACAD9 0.46 6.22 0.32 1.44e-9 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23803311 chr5:147763284 FBXO38 0.43 6.27 0.32 1.11e-9 Cognitive function; LIHC cis rs6500602 0.702 rs56895104 chr16:4548132 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.41 0.33 4.83e-10 Schizophrenia; LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg23283495 chr1:209979779 IRF6 0.46 7.38 0.37 1.21e-12 Cleft lip with or without cleft palate; LIHC cis rs55665837 0.520 rs10766189 chr11:14733923 G/A cg16394018 chr11:14927549 NA 0.4 5.72 0.3 2.27e-8 Vitamin D levels; LIHC cis rs7020830 0.898 rs13284651 chr9:37222681 G/T cg14294708 chr9:37120828 ZCCHC7 -1.07 -22.47 -0.77 2.53e-69 Schizophrenia; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.46 0.62 2.68e-37 Prudent dietary pattern; LIHC cis rs921968 0.541 rs12617603 chr2:219369288 A/G cg02176678 chr2:219576539 TTLL4 -0.55 -7.7 -0.38 1.5e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7617773 0.780 rs11718350 chr3:48360992 T/G cg11946769 chr3:48343235 NME6 0.91 11.52 0.53 3.48e-26 Coronary artery disease; LIHC cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs7587476 1.000 rs3768707 chr2:215645135 C/T cg04530015 chr2:215796436 ABCA12 -0.4 -6.55 -0.33 2.12e-10 Neuroblastoma; LIHC cis rs920590 0.758 rs1907799 chr8:19664668 A/G cg03894339 chr8:19674705 INTS10 -0.59 -9.62 -0.46 1.5700000000000001e-19 Acute lymphoblastic leukemia (childhood); LIHC cis rs539514 0.637 rs552030 chr13:76322065 G/T cg04757411 chr13:76259545 LMO7 -0.42 -7.13 -0.36 5.87e-12 Type 1 diabetes; LIHC cis rs10883723 0.810 rs10786671 chr10:104271303 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.05 0.58 7.58e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7429990 0.932 rs6766641 chr3:48145224 G/A cg11946769 chr3:48343235 NME6 -0.48 -6.17 -0.32 1.96e-9 Educational attainment (years of education); LIHC cis rs8017423 0.967 rs11628881 chr14:90713833 C/T cg04374321 chr14:90722782 PSMC1 0.75 14.71 0.62 2.72e-38 Mortality in heart failure; LIHC cis rs11098499 0.644 rs7693919 chr4:120540571 G/A cg09307838 chr4:120376055 NA 0.67 10.29 0.49 8.05e-22 Corneal astigmatism; LIHC cis rs950169 0.881 rs4842852 chr15:84941961 A/G cg17507749 chr15:85114479 UBE2QP1 0.74 8.65 0.42 2.04e-16 Schizophrenia; LIHC trans rs72960926 0.744 rs3897895 chr6:74917550 C/T cg07247405 chr1:2484626 LOC115110 0.52 6.17 0.32 1.93e-9 Metabolite levels (MHPG); LIHC cis rs4665809 0.877 rs34536218 chr2:26287376 T/A cg27170947 chr2:26402098 FAM59B 0.56 6.06 0.31 3.69e-9 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg11062466 chr8:58055876 NA 0.54 7.69 0.38 1.61e-13 Developmental language disorder (linguistic errors); LIHC cis rs477895 0.838 rs11605738 chr11:64013406 G/A cg04317338 chr11:64019027 PLCB3 0.87 10.6 0.5 6.69e-23 Mean platelet volume; LIHC cis rs634534 0.622 rs501353 chr11:65739549 T/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.44 6.95 0.35 1.88e-11 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs5756813 1.000 rs1074407 chr22:38156183 T/A cg19894588 chr14:64061835 NA 0.65 9.94 0.47 1.23e-20 Optic cup area;Vertical cup-disc ratio; LIHC cis rs1336900 0.641 rs6587756 chr1:150546865 A/T cg13175981 chr1:150552382 MCL1 0.54 7.26 0.37 2.62e-12 Blood protein levels; LIHC cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg06634786 chr22:41940651 POLR3H 0.8 8.85 0.43 4.81e-17 Vitiligo; LIHC cis rs17106184 1.000 rs72902729 chr1:51231935 A/G cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg06640241 chr16:89574553 SPG7 0.82 14.59 0.62 7.86e-38 Multiple myeloma (IgH translocation); LIHC cis rs6754311 0.773 rs309180 chr2:136614255 A/G cg07169764 chr2:136633963 MCM6 0.65 9.91 0.47 1.61e-20 Mosquito bite size; LIHC cis rs6964587 1.000 rs6970277 chr7:91680655 T/C cg17063962 chr7:91808500 NA 1.02 19.46 0.72 2.57e-57 Breast cancer; LIHC cis rs10751667 0.961 rs10902263 chr11:992691 A/C cg06064525 chr11:970664 AP2A2 0.5 12.5 0.56 8.99e-30 Alzheimer's disease (late onset); LIHC cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg03517284 chr6:25882590 NA 0.5 6.27 0.32 1.08e-9 Intelligence (multi-trait analysis); LIHC cis rs61542988 0.606 rs4722185 chr7:22832711 G/A cg11367502 chr7:22862612 TOMM7 0.58 9.37 0.45 9.77e-19 Fibrinogen levels; LIHC trans rs867371 1.000 rs2867579 chr15:82475384 G/C cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.75 -0.34 6.31e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs3960554 0.808 rs13438599 chr7:75768022 G/A cg19862616 chr7:65841803 NCRNA00174 0.6 8.28 0.41 2.77e-15 Eotaxin levels; LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg07157834 chr1:205819609 PM20D1 0.66 9.91 0.47 1.57e-20 Menarche (age at onset); LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg04701394 chr12:92489468 NA 0.43 6.23 0.32 1.38e-9 Myopia (pathological); LIHC cis rs10484885 0.878 rs72921916 chr6:90555990 C/T cg13799429 chr6:90582589 CASP8AP2 -0.69 -6.36 -0.33 6.49e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7223966 1.000 rs8070650 chr17:61744040 A/G cg05941027 chr17:61774174 LIMD2 0.33 6.71 0.34 8.24e-11 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs11098499 0.913 rs10006304 chr4:120124305 A/G cg25214090 chr10:38739885 LOC399744 0.46 7.45 0.37 7.5e-13 Corneal astigmatism; LIHC cis rs1144333 1.000 rs75399471 chr1:76339092 A/T cg22875332 chr1:76189707 ACADM 0.44 6.44 0.33 4.14e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg20090690 chr10:134436459 INPP5A 0.44 5.77 0.3 1.76e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs3852053 1.000 rs3852053 chr3:186937200 A/C cg12634932 chr5:43397230 CCL28 0.45 6.25 0.32 1.25e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs9649213 0.593 rs7795176 chr7:97978287 A/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.24e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg03264133 chr6:25882463 NA -0.63 -8.85 -0.43 4.88e-17 Blood metabolite levels; LIHC cis rs546131 0.642 rs566798 chr11:34852277 A/G cg06937548 chr11:34938143 PDHX;APIP -0.56 -7.17 -0.36 4.58e-12 Lung disease severity in cystic fibrosis; LIHC cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.59 -0.46 1.87e-19 Initial pursuit acceleration; LIHC cis rs2228479 0.702 rs62052710 chr16:89854893 C/T cg06558623 chr16:89946397 TCF25 0.84 10.93 0.51 4.91e-24 Skin colour saturation; LIHC cis rs2274273 0.684 rs2340921 chr14:55563705 A/G cg01864836 chr14:55583639 NA -0.36 -6.68 -0.34 9.45e-11 Protein biomarker; LIHC cis rs10916814 0.610 rs1890005 chr1:20899016 T/C cg24502330 chr1:20914028 CDA -0.3 -6.7 -0.34 8.63e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10751667 0.714 rs7395879 chr11:963855 G/C ch.11.42038R chr11:967971 AP2A2 0.56 10.13 0.48 2.88e-21 Alzheimer's disease (late onset); LIHC cis rs11971779 0.588 rs6972408 chr7:139071474 T/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg27286337 chr10:134555280 INPP5A 0.87 13.54 0.59 9.67e-34 Migraine; LIHC cis rs7312933 0.703 rs12370778 chr12:42599696 T/A cg17420585 chr12:42539391 GXYLT1 -0.37 -5.9 -0.3 8.94e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.81 8.04 0.4 1.49e-14 Platelet count; LIHC cis rs9560113 1.000 rs11620313 chr13:112179363 G/A cg14154082 chr13:112174009 NA 0.29 6.15 0.32 2.13e-9 Menarche (age at onset); LIHC trans rs637571 0.544 rs56239996 chr11:65730003 A/T cg17712092 chr4:129076599 LARP1B 0.75 13.27 0.58 1.08e-32 Eosinophil percentage of white cells; LIHC cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg16049864 chr8:95962084 TP53INP1 -0.66 -13.04 -0.58 7.95e-32 Type 2 diabetes; LIHC cis rs11077998 1.000 rs11077998 chr17:80483946 C/G cg10255544 chr17:80519551 FOXK2 -0.47 -8.61 -0.42 2.72e-16 Reticulocyte fraction of red cells; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg05484376 chr2:27715224 FNDC4 -0.38 -6.46 -0.33 3.63e-10 Total body bone mineral density; LIHC cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg03735888 chr19:58951602 ZNF132 0.39 6.59 0.34 1.67e-10 Uric acid clearance; LIHC cis rs1865760 0.927 rs6915834 chr6:25935427 A/C cg03264133 chr6:25882463 NA -0.41 -6.22 -0.32 1.48e-9 Height; LIHC cis rs3892630 0.588 rs7245709 chr19:33242755 C/T cg22980127 chr19:33182716 NUDT19 1.06 13.86 0.6 5.48e-35 Red blood cell traits; LIHC cis rs860295 0.627 rs11264410 chr1:155745349 G/A cg02153340 chr1:155202674 NA -0.36 -6.54 -0.33 2.26e-10 Body mass index; LIHC cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg13770153 chr20:60521292 NA 0.38 7.4 0.37 1.09e-12 Body mass index; LIHC cis rs4689592 0.587 rs6825954 chr4:7074226 T/C cg26116260 chr4:7069785 GRPEL1 0.98 17.59 0.69 9.08e-50 Monocyte percentage of white cells; LIHC cis rs11785400 0.928 rs750529 chr8:143744877 G/C cg10596483 chr8:143751796 JRK 0.51 8.32 0.41 2.06e-15 Schizophrenia; LIHC cis rs2073300 1.000 rs6137959 chr20:23442640 T/C cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs7552404 0.731 rs61770556 chr1:76421902 T/C cg10523679 chr1:76189770 ACADM 0.58 6.82 0.35 4.24e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs116095464 0.558 rs10057674 chr5:266813 C/T cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01398529 chr4:26322459 RBPJ 0.49 6.31 0.32 8.73e-10 Lung function (FEV1/FVC); LIHC trans rs412658 0.812 rs17554725 chr19:22317759 A/G cg17074339 chr11:11642133 GALNTL4 -0.48 -7.1 -0.36 7.41e-12 Telomere length; LIHC cis rs7847628 0.587 rs3793638 chr9:123582697 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.76 13.02 0.58 9.61e-32 Birth weight; LIHC cis rs10078 0.559 rs2037077 chr5:447226 A/G cg07599136 chr5:415885 AHRR 0.81 13.16 0.58 2.86e-32 Fat distribution (HIV); LIHC cis rs2204008 0.744 rs11181635 chr12:38378420 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 2.97e-23 Bladder cancer; LIHC trans rs903027 0.752 rs11774171 chr8:62477247 C/T cg25338577 chr2:201391149 SGOL2 0.47 7.12 0.36 6.22e-12 Whole-brain volume; LIHC cis rs34172651 0.687 rs8044992 chr16:24811207 T/C cg00152838 chr16:24741724 TNRC6A -0.51 -6.96 -0.35 1.72e-11 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.5 0.77 1.96e-69 Height; LIHC cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg05665937 chr4:1216051 CTBP1 0.39 6.2 0.32 1.59e-9 Obesity-related traits; LIHC cis rs2645694 0.626 rs2703136 chr4:77828957 T/A cg03477792 chr4:77819574 ANKRD56 0.58 7.73 0.39 1.18e-13 Emphysema distribution in smoking; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg16246252 chr11:119535621 PVRL1 0.36 6.17 0.32 1.92e-9 Calcium levels; LIHC cis rs57920188 0.568 rs10915665 chr1:4093717 G/T cg20703997 chr1:4087676 NA 0.49 5.86 0.3 1.07e-8 Interleukin-17 levels; LIHC cis rs1003719 0.591 rs2835633 chr21:38525019 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.83 -0.51 1.09e-23 Eye color traits; LIHC cis rs2251381 0.808 rs7364112 chr21:30548968 C/A cg08807101 chr21:30365312 RNF160 0.74 9.48 0.46 4.39e-19 Selective IgA deficiency; LIHC cis rs35110281 0.748 rs2838322 chr21:44998615 G/C cg04455712 chr21:45112962 RRP1B 0.49 8.19 0.41 5.13e-15 Mean corpuscular volume; LIHC cis rs3917254 0.543 rs11123911 chr2:102761538 C/T cg22835712 chr2:102737379 NA -0.47 -5.81 -0.3 1.42e-8 Blood protein levels; LIHC cis rs61160187 0.522 rs2045356 chr5:59947354 C/T cg02684056 chr5:59996105 DEPDC1B 0.42 5.9 0.3 8.62e-9 Educational attainment (years of education);Educational attainment (college completion); LIHC cis rs7246657 1.000 rs35398388 chr19:37740358 A/G cg23950597 chr19:37808831 NA -0.52 -6.63 -0.34 1.34e-10 Coronary artery calcification; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg11494091 chr17:61959527 GH2 0.36 6.1 0.31 2.85e-9 Height; LIHC cis rs9896052 0.580 rs8078577 chr17:73464294 G/T cg25649188 chr17:73499917 CASKIN2 0.48 7.16 0.36 5.1e-12 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs765787 0.530 rs1706764 chr15:45524256 T/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.5 -0.38 5.73e-13 Uric acid levels; LIHC cis rs4240897 0.935 rs4846082 chr1:12042443 C/T cg13216073 chr1:12042593 MFN2 0.47 7.71 0.38 1.4e-13 Tuberculosis; LIHC cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg07061783 chr6:25882402 NA -0.43 -6.05 -0.31 3.77e-9 Blood metabolite levels; LIHC cis rs9611519 1.000 rs6002271 chr22:41566595 C/T cg03806693 chr22:41940476 POLR3H -0.67 -7.15 -0.36 5.13e-12 Neuroticism; LIHC cis rs17401966 0.964 rs17400510 chr1:10290421 T/C cg15208524 chr1:10270712 KIF1B 0.44 6.38 0.33 5.61e-10 Hepatocellular carcinoma; LIHC cis rs6835098 0.962 rs10027704 chr4:174083107 T/C cg08422745 chr4:174089978 GALNT7 -0.32 -5.71 -0.3 2.43e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs8067354 0.507 rs72840511 chr17:57806011 G/T cg02344993 chr17:57696989 CLTC 0.72 12.1 0.55 2.68e-28 Hemoglobin concentration; LIHC cis rs838721 0.574 rs11679046 chr2:234258101 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.4 5.71 0.3 2.4e-8 Total body bone mineral density; LIHC cis rs7927592 0.913 rs67947146 chr11:68314980 C/T cg16797656 chr11:68205561 LRP5 0.51 8.04 0.4 1.47e-14 Total body bone mineral density; LIHC cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg20607798 chr8:58055168 NA 0.59 6.91 0.35 2.36e-11 Developmental language disorder (linguistic errors); LIHC cis rs912057 0.833 rs1294421 chr6:6743149 A/C cg06612196 chr6:6737390 NA 0.52 9.85 0.47 2.52e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs2836950 0.501 rs4818018 chr21:40694072 C/T cg11890956 chr21:40555474 PSMG1 -0.41 -6.66 -0.34 1.08e-10 Menarche (age at onset); LIHC cis rs6701037 0.748 rs10912901 chr1:175138602 G/A cg00321850 chr1:175162397 KIAA0040 -0.47 -7.33 -0.37 1.65e-12 Alcohol dependence; LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg07133347 chr1:107600762 PRMT6 0.45 6.73 0.34 6.98e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg21724239 chr8:58056113 NA 0.57 7.62 0.38 2.58e-13 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg02951883 chr7:2050386 MAD1L1 -0.76 -13.15 -0.58 3.05e-32 Bipolar disorder and schizophrenia; LIHC cis rs9911578 0.967 rs6503890 chr17:57064167 A/G cg12560992 chr17:57184187 TRIM37 0.97 17.27 0.68 1.7e-48 Intelligence (multi-trait analysis); LIHC cis rs225245 0.782 rs321618 chr17:33912404 A/G cg05299278 chr17:33885742 SLFN14 0.22 5.78 0.3 1.66e-8 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs11628318 0.853 rs6575925 chr14:103034507 C/T cg01864069 chr14:103024347 NA -0.54 -8.97 -0.44 2.02e-17 Platelet count; LIHC cis rs6860806 0.507 rs273915 chr5:131660119 G/C cg24060327 chr5:131705240 SLC22A5 -0.82 -12.88 -0.57 3.09e-31 Breast cancer; LIHC cis rs8062405 1.000 rs3088215 chr16:28853996 A/C cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3862260 0.509 rs10754416 chr1:120163531 A/G cg11530693 chr1:120165357 ZNF697 0.47 7.36 0.37 1.34e-12 Systemic lupus erythematosus; LIHC trans rs1005277 0.579 rs2472173 chr10:38374638 G/A cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg09367891 chr1:107599246 PRMT6 -0.67 -10.87 -0.51 7.54e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11676348 0.729 rs13013361 chr2:218947515 A/T cg00012203 chr2:219082015 ARPC2 -0.46 -6.37 -0.33 6.21e-10 Ulcerative colitis; LIHC cis rs9297145 0.916 rs4236540 chr7:98769025 A/C cg05967295 chr7:98741636 SMURF1 0.7 11.78 0.54 4.2e-27 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs9470366 0.527 rs10807170 chr6:36629444 C/T cg00935119 chr6:36647544 CDKN1A 0.41 5.94 0.31 7.14e-9 QRS duration; LIHC cis rs332507 0.830 rs3772781 chr3:124387439 G/T cg05980111 chr3:124395277 KALRN 0.46 7.11 0.36 6.65e-12 Plateletcrit; LIHC cis rs4742903 0.904 rs7047747 chr9:106939922 G/A cg14250997 chr9:106856677 SMC2 0.35 5.94 0.31 7.03e-9 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19259030 chr15:76553926 ETFA;TYRO3P -0.35 -6.15 -0.32 2.15e-9 Calcium levels; LIHC cis rs858239 0.601 rs764533 chr7:23153875 C/T cg23682824 chr7:23144976 KLHL7 0.4 6.01 0.31 4.76e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7100689 1.000 rs7100689 chr10:82222178 C/A cg01528321 chr10:82214614 TSPAN14 1.14 15.15 0.63 4.96e-40 Post bronchodilator FEV1; LIHC cis rs7044106 0.791 rs7043969 chr9:123493989 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.78 13.2 0.58 1.95e-32 Hip circumference adjusted for BMI; LIHC cis rs7619427 0.908 rs9682281 chr3:44082811 A/T cg24966902 chr3:44043705 NA 0.43 6.17 0.32 1.95e-9 Schizophrenia; LIHC cis rs919433 0.713 rs10178946 chr2:198463090 G/T cg03934865 chr2:198174659 NA 0.51 7.86 0.39 4.97e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs62380364 0.602 rs591228 chr5:88064809 G/A cg22951263 chr5:87985283 NA -0.41 -7.18 -0.36 4.38e-12 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg14004847 chr7:1930337 MAD1L1 -0.48 -7.18 -0.36 4.37e-12 Bipolar disorder and schizophrenia; LIHC cis rs11583043 0.958 rs11583674 chr1:101396560 C/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.42 0.41 1.05e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg23172400 chr8:95962367 TP53INP1 0.38 7.64 0.38 2.27e-13 Type 2 diabetes; LIHC cis rs9790314 0.871 rs336561 chr3:161125305 C/T cg03342759 chr3:160939853 NMD3 -0.64 -7.76 -0.39 9.72e-14 Morning vs. evening chronotype; LIHC cis rs10089 1.000 rs1962291 chr5:127445373 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.54 -6.61 -0.34 1.44e-10 Ileal carcinoids; LIHC cis rs7927771 0.864 rs11604680 chr11:47457539 A/G cg20135002 chr11:47629003 NA -0.59 -9.99 -0.48 8.61e-21 Subjective well-being; LIHC cis rs7116495 1.000 rs2508858 chr11:71805405 C/G cg26138937 chr11:71823887 C11orf51 0.8 7.88 0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs12477438 0.520 rs6739579 chr2:99731552 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.4 0.77 4.86e-69 Chronic sinus infection; LIHC trans rs17034615 0.510 rs17034560 chr1:10229158 A/G cg13617753 chr19:58096512 ZIK1 -0.5 -6.09 -0.31 3.09e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs11122272 0.735 rs1416916 chr1:231533027 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.73e-19 Hemoglobin concentration; LIHC cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.3 0.45 1.74e-18 Bipolar disorder; LIHC cis rs1799949 0.965 rs8070179 chr17:41202688 G/A cg25072359 chr17:41440525 NA 0.4 6.39 0.33 5.36e-10 Menopause (age at onset); LIHC trans rs208520 1.000 rs12193077 chr6:66989548 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.07 0.36 8.67e-12 Exhaled nitric oxide output; LIHC cis rs17685 0.712 rs56965035 chr7:75795670 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.33 -0.32 7.51e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7552404 0.727 rs2172507 chr1:76331320 A/G cg10523679 chr1:76189770 ACADM -0.56 -7.17 -0.36 4.67e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7582180 0.663 rs4850929 chr2:100990707 A/C cg14675211 chr2:100938903 LONRF2 0.56 8.23 0.41 3.98e-15 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg18279126 chr7:2041391 MAD1L1 0.39 6.51 0.33 2.69e-10 Bipolar disorder and schizophrenia; LIHC cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg23758822 chr17:41437982 NA 0.94 17.9 0.7 5.08e-51 Menopause (age at onset); LIHC cis rs2404602 0.710 rs2469541 chr15:76562118 C/T cg03037974 chr15:76606532 NA -0.81 -18.16 -0.7 4.36e-52 Blood metabolite levels; LIHC cis rs8180040 1.000 rs8180040 chr3:47388947 A/T cg16586182 chr3:47516702 SCAP -0.58 -10.97 -0.51 3.32e-24 Colorectal cancer; LIHC cis rs8141529 0.702 rs469991 chr22:29307859 G/C cg02153584 chr22:29168773 CCDC117 -0.52 -8.05 -0.4 1.39e-14 Lymphocyte counts; LIHC cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg18357526 chr6:26021779 HIST1H4A -0.53 -6.46 -0.33 3.61e-10 Blood metabolite levels; LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg00612595 chr21:47717864 NA -0.4 -6.76 -0.34 5.88e-11 Testicular germ cell tumor; LIHC cis rs2262909 0.962 rs439574 chr19:22232024 A/C cg11619707 chr19:22235551 ZNF257 -0.32 -5.82 -0.3 1.37e-8 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs7772486 0.534 rs34541797 chr6:146205304 A/G cg23711669 chr6:146136114 FBXO30 0.64 9.55 0.46 2.62e-19 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15459742 chr9:111775564 CTNNAL1 0.41 6.34 0.32 7.39e-10 Pancreatic cancer; LIHC cis rs546131 0.928 rs483976 chr11:34840167 C/G cg11058730 chr11:34937778 PDHX;APIP 0.6 9.23 0.45 2.98e-18 Lung disease severity in cystic fibrosis; LIHC cis rs8044995 0.563 rs3785127 chr16:68399590 C/G cg09835421 chr16:68378352 PRMT7 -0.82 -9.6 -0.46 1.8e-19 Schizophrenia; LIHC cis rs9640161 0.750 rs11538922 chr7:150035183 C/T cg27494647 chr7:150038898 RARRES2 0.34 6.15 0.32 2.16e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs7258465 1.000 rs3810429 chr19:18543270 G/T cg10790698 chr19:18539756 SSBP4 -0.36 -7.25 -0.36 2.8e-12 Breast cancer; LIHC cis rs8081395 0.711 rs11368 chr17:58031412 A/G cg02344993 chr17:57696989 CLTC 0.36 5.85 0.3 1.14e-8 White blood cell count; LIHC cis rs2204008 0.837 rs11168334 chr12:37961768 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.82 0.51 1.12e-23 Bladder cancer; LIHC cis rs13064411 0.696 rs7610638 chr3:113139656 A/G cg18753928 chr3:113234510 CCDC52 -0.42 -5.71 -0.3 2.45e-8 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs477895 0.941 rs35692796 chr11:64110805 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 6.76 0.34 6.01e-11 Mean platelet volume; LIHC cis rs7937682 0.961 rs4936682 chr11:111629743 T/G cg09085632 chr11:111637200 PPP2R1B 1.21 19.87 0.73 5.66e-59 Primary sclerosing cholangitis; LIHC cis rs3749237 0.595 rs4855861 chr3:49525962 G/T cg06212747 chr3:49208901 KLHDC8B 0.46 6.01 0.31 4.66e-9 Resting heart rate; LIHC cis rs12744310 1.000 rs12739950 chr1:41759891 C/T cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.72e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs17685 0.753 rs2868203 chr7:75680026 G/A cg04592579 chr7:75616294 TMEM120A -0.4 -7.0 -0.35 1.32e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg10802521 chr3:52805072 NEK4 -0.37 -5.81 -0.3 1.41e-8 Bipolar disorder; LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs7666738 0.618 rs10856932 chr4:98819992 C/T cg05340658 chr4:99064831 C4orf37 0.63 11.49 0.53 4.74e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs892961 0.965 rs312856 chr17:75401598 A/G cg05865280 chr17:75406074 SEPT9 0.57 15.02 0.63 1.62e-39 Airflow obstruction; LIHC cis rs2710642 0.576 rs6545968 chr2:62871184 C/A cg17519650 chr2:63277830 OTX1 0.5 7.27 0.37 2.39e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1144333 0.655 rs77244403 chr1:76304872 A/G cg10523679 chr1:76189770 ACADM 0.44 5.95 0.31 6.73e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7520050 0.931 rs785472 chr1:46518288 T/A cg03146154 chr1:46216737 IPP -0.36 -5.94 -0.31 7.06e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7100689 0.646 rs1538819 chr10:82122523 A/G cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs17253792 0.545 rs12879705 chr14:56017684 C/G cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg06466757 chr4:1255808 NA 0.34 5.8 0.3 1.53e-8 Obesity-related traits; LIHC cis rs67478160 0.619 rs10083367 chr14:104314183 C/G cg01849466 chr14:104193079 ZFYVE21 0.48 7.59 0.38 3.01e-13 Schizophrenia; LIHC cis rs28830936 0.966 rs2241522 chr15:42127734 A/G cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.86 -0.3 1.11e-8 Diastolic blood pressure; LIHC cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs34172651 0.517 rs2303084 chr16:24834581 G/C cg00339695 chr16:24857497 SLC5A11 0.75 10.49 0.49 1.65e-22 Intelligence (multi-trait analysis); LIHC cis rs17125944 0.505 rs75838476 chr14:53242362 G/A cg00686598 chr14:53173677 PSMC6 1.27 15.78 0.65 1.51e-42 Alzheimer's disease (late onset); LIHC cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs722599 0.748 rs731952 chr14:75366447 A/G cg08847533 chr14:75593920 NEK9 0.52 8.73 0.43 1.12e-16 IgG glycosylation; LIHC cis rs240764 0.658 rs12213201 chr6:101176285 C/A cg09795085 chr6:101329169 ASCC3 -0.45 -6.46 -0.33 3.5e-10 Neuroticism; LIHC cis rs17401966 0.838 rs4475756 chr1:10387788 A/G cg19773385 chr1:10388646 KIF1B -0.39 -6.93 -0.35 2.05e-11 Hepatocellular carcinoma; LIHC cis rs4407350 0.933 rs5765732 chr22:44922761 A/G cg11695653 chr22:44894386 LDOC1L -0.38 -6.22 -0.32 1.47e-9 Intelligence (multi-trait analysis); LIHC cis rs736408 0.812 rs2240920 chr3:52831009 A/G cg18404041 chr3:52824283 ITIH1 0.53 8.52 0.42 5.02e-16 Bipolar disorder; LIHC cis rs67478160 0.619 rs10083370 chr14:104314182 G/A cg01849466 chr14:104193079 ZFYVE21 0.48 7.59 0.38 3.01e-13 Schizophrenia; LIHC cis rs2668423 0.502 rs2074898 chr19:1391361 A/G cg02639931 chr19:1387894 NDUFS7 -0.85 -16.17 -0.66 4.54e-44 Nonalcoholic fatty liver disease; LIHC cis rs6939532 0.522 rs9358933 chr6:26363688 C/T cg14345882 chr6:26364793 BTN3A2 0.39 5.76 0.3 1.88e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs6831352 0.918 rs17218288 chr4:100058030 A/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs6690583 0.623 rs75918067 chr1:85453413 T/C cg22153463 chr1:85462885 MCOLN2 0.51 6.1 0.31 2.92e-9 Serum sulfate level; LIHC cis rs3770081 1.000 rs111295372 chr2:86283357 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.95 -11.58 -0.53 2.24e-26 Facial emotion recognition (sad faces); LIHC cis rs9790314 0.613 rs4679666 chr3:160629025 C/G cg03342759 chr3:160939853 NMD3 0.54 7.19 0.36 4.05e-12 Morning vs. evening chronotype; LIHC cis rs2153535 0.525 rs1335644 chr6:8488041 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs9381040 0.610 rs4140580 chr6:41041742 C/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.3 -0.32 9.3e-10 Alzheimer's disease (late onset); LIHC cis rs7107174 1.000 rs10899476 chr11:78051794 A/G cg02023728 chr11:77925099 USP35 0.47 8.83 0.43 5.41e-17 Testicular germ cell tumor; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg06873352 chr17:61820015 STRADA 0.71 12.65 0.56 2.48e-30 Prudent dietary pattern; LIHC cis rs8180040 0.966 rs13075233 chr3:47420627 T/C cg27129171 chr3:47204927 SETD2 0.56 9.49 0.46 4.11e-19 Colorectal cancer; LIHC cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg16497277 chr3:49208875 KLHDC8B -0.49 -5.88 -0.3 9.51e-9 Parkinson's disease; LIHC cis rs4891159 0.526 rs2848961 chr18:74129886 C/G cg24786174 chr18:74118243 ZNF516 -0.83 -16.79 -0.67 1.47e-46 Longevity; LIHC cis rs965469 1.000 rs6051751 chr20:3310049 G/C cg25506879 chr20:3388711 C20orf194 -0.57 -6.83 -0.35 3.86e-11 IFN-related cytopenia; LIHC cis rs7520050 0.966 rs6677007 chr1:46400590 A/G cg03146154 chr1:46216737 IPP -0.38 -6.25 -0.32 1.21e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1008375 0.932 rs4698627 chr4:17605959 T/C cg16339924 chr4:17578868 LAP3 0.41 5.75 0.3 1.93e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs6582630 0.576 rs2387836 chr12:38560070 A/G cg05848834 chr11:43543746 NA 0.31 6.25 0.32 1.21e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7572733 0.515 rs893808 chr2:198860837 C/G cg03934865 chr2:198174659 NA 0.46 6.61 0.34 1.44e-10 Dermatomyositis; LIHC cis rs7395581 0.879 rs3758673 chr11:47278917 C/T cg26139080 chr11:47293733 MADD -0.5 -8.53 -0.42 4.94e-16 HDL cholesterol; LIHC cis rs941873 0.836 rs6480931 chr10:81108482 T/C cg09469691 chr10:81107165 PPIF 0.7 10.58 0.5 8.1e-23 Height; LIHC cis rs9583531 0.689 rs9521905 chr13:111352600 G/A cg24331049 chr13:111365604 ING1 -0.75 -11.62 -0.53 1.55e-26 Coronary artery disease; LIHC cis rs1018836 0.923 rs4735260 chr8:91617157 C/G cg16814680 chr8:91681699 NA 0.67 10.82 0.51 1.14e-23 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg03721293 chr16:90014378 DEF8 0.36 6.31 0.32 8.77e-10 Skin colour saturation; LIHC cis rs7613875 0.600 rs1138536 chr3:50153356 C/T cg24110177 chr3:50126178 RBM5 -0.56 -9.2 -0.45 3.75e-18 Body mass index; LIHC cis rs703842 1.000 rs2072052 chr12:58146719 A/C cg18357645 chr12:58087776 OS9 -0.47 -7.1 -0.36 7.22e-12 Multiple sclerosis; LIHC cis rs763014 0.932 rs2269559 chr16:682297 T/C cg00802000 chr16:706648 WDR90 -0.39 -6.29 -0.32 9.45e-10 Height; LIHC cis rs1204798 0.617 rs6909152 chr6:116601557 A/G cg23214565 chr6:116600728 DSE;TSPYL1 -0.41 -6.07 -0.31 3.45e-9 Dental caries; LIHC cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2180341 0.960 rs6900074 chr6:127685893 A/G cg24812749 chr6:127587940 RNF146 1.06 15.49 0.64 2.27e-41 Breast cancer; LIHC cis rs7511006 1.000 rs7511006 chr22:50676259 T/C cg07895657 chr22:50616420 PANX2 -0.34 -5.73 -0.3 2.25e-8 Obesity-related traits; LIHC trans rs2749592 0.550 rs12255038 chr10:37869332 T/C cg17830980 chr10:43048298 ZNF37B 0.42 7.91 0.39 3.5e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2933343 0.729 rs1680794 chr3:128620390 A/G cg24203234 chr3:128598194 ACAD9 0.45 6.29 0.32 9.67e-10 IgG glycosylation; LIHC cis rs17428076 0.831 rs3736499 chr2:172690418 C/T cg13550731 chr2:172543902 DYNC1I2 0.38 6.22 0.32 1.47e-9 Myopia; LIHC cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.04 -0.48 5.96e-21 Platelet count; LIHC cis rs8114671 0.836 rs6142294 chr20:33671497 A/G cg07148914 chr20:33460835 GGT7 -0.56 -8.41 -0.41 1.12e-15 Height; LIHC cis rs8067354 0.645 rs2173120 chr17:57892640 A/T cg13753209 chr17:57696993 CLTC 0.77 12.28 0.55 6.02e-29 Hemoglobin concentration; LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg06558623 chr16:89946397 TCF25 0.95 14.44 0.62 3.05e-37 Skin colour saturation; LIHC cis rs12478296 0.901 rs67423532 chr2:243004719 A/G cg06360820 chr2:242988706 NA -0.82 -12.26 -0.55 6.88e-29 Obesity-related traits; LIHC trans rs2243480 1.000 rs2707844 chr7:66059509 G/A cg07424592 chr7:64974309 NA 0.77 8.87 0.43 4.13e-17 Diabetic kidney disease; LIHC cis rs17095355 1.000 rs13377169 chr10:111729414 A/G cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.96 -0.31 6.35e-9 Biliary atresia; LIHC cis rs1552244 0.816 rs17050701 chr3:10041554 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs4555082 0.957 rs2816622 chr14:105733114 T/C cg10792982 chr14:105748885 BRF1 0.44 6.02 0.31 4.43e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs8017423 0.967 rs55667096 chr14:90714798 C/T cg14092571 chr14:90743983 NA -0.37 -5.88 -0.3 9.67e-9 Mortality in heart failure; LIHC cis rs9583531 0.689 rs9515273 chr13:111383427 G/C cg15841412 chr13:111365552 ING1 0.53 6.46 0.33 3.6e-10 Coronary artery disease; LIHC cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.83 -0.35 3.84e-11 Gut microbiome composition (summer); LIHC cis rs6748734 1.000 rs10933518 chr2:241838091 A/C cg04034577 chr2:241836375 C2orf54 -0.49 -11.29 -0.52 2.46e-25 Urinary metabolites; LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.61 -8.68 -0.42 1.67e-16 Lymphocyte counts; LIHC cis rs10504073 0.584 rs1511368 chr8:49949523 A/T cg00325661 chr8:49890786 NA 0.34 7.78 0.39 8.88e-14 Blood metabolite ratios; LIHC cis rs10744422 1.000 rs7294991 chr12:123286780 C/T cg25930673 chr12:123319894 HIP1R -0.87 -10.46 -0.49 2.1e-22 Schizophrenia; LIHC cis rs7089973 0.604 rs58587374 chr10:116597572 A/G cg23260525 chr10:116636907 FAM160B1 0.35 7.05 0.36 1.02e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs1005277 0.579 rs2474580 chr10:38398713 G/A cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg06634786 chr22:41940651 POLR3H -0.81 -8.95 -0.44 2.26e-17 Vitiligo; LIHC cis rs12474201 0.822 rs897530 chr2:46948150 C/G cg06386533 chr2:46925753 SOCS5 0.68 7.84 0.39 5.76e-14 Height; LIHC cis rs600806 0.683 rs10857788 chr1:110012289 G/A cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.34 -0.32 7.42e-10 Intelligence (multi-trait analysis); LIHC cis rs1790761 0.692 rs10896179 chr11:67316928 C/A cg21734168 chr11:67353974 GSTP1 -0.26 -6.49 -0.33 3.07e-10 Mean corpuscular volume; LIHC cis rs17401966 0.838 rs1013952 chr1:10319247 G/A cg15208524 chr1:10270712 KIF1B 0.37 5.72 0.3 2.3e-8 Hepatocellular carcinoma; LIHC cis rs9814567 0.806 rs1880374 chr3:134322113 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4129767 0.869 rs4969142 chr17:76398304 G/A cg20026190 chr17:76395443 PGS1 0.4 5.92 0.3 8.01e-9 HDL cholesterol; LIHC cis rs317689 0.819 rs317660 chr12:69686203 G/A cg20891283 chr12:69753455 YEATS4 0.57 8.24 0.41 3.74e-15 Response to diuretic therapy; LIHC cis rs6695567 0.902 rs6588469 chr1:53630705 C/T cg20326410 chr1:53600821 SLC1A7 0.3 6.34 0.32 7.22e-10 Systemic lupus erythematosus; LIHC cis rs151997 1.000 rs152690 chr5:50213584 A/T cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg00149659 chr3:10157352 C3orf10 0.68 6.93 0.35 2.11e-11 Alzheimer's disease; LIHC cis rs2439831 0.867 rs16957632 chr15:43642897 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs6665290 0.582 rs72764213 chr1:227207391 C/T cg10327440 chr1:227177885 CDC42BPA -1.14 -22.29 -0.77 1.37e-68 Myeloid white cell count; LIHC cis rs11190604 0.767 rs7078070 chr10:102166415 A/C cg07080220 chr10:102295463 HIF1AN 0.45 6.13 0.31 2.39e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs16854884 0.657 rs6791078 chr3:143736876 A/G cg06585982 chr3:143692056 C3orf58 0.55 7.15 0.36 5.36e-12 Economic and political preferences (feminism/equality); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg16466278 chr15:43429893 TMEM62 0.38 6.16 0.32 2.02e-9 Bilirubin levels; LIHC cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.11 -0.44 6.94e-18 Bipolar disorder; LIHC cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg07092213 chr7:1199455 ZFAND2A -0.44 -6.75 -0.34 6.37e-11 Longevity;Endometriosis; LIHC cis rs6433857 0.627 rs6741769 chr2:181500545 G/A cg23363182 chr2:181467187 NA -0.36 -5.84 -0.3 1.2e-8 Body mass index; LIHC cis rs6952808 0.609 rs4721190 chr7:1954732 A/G cg21782813 chr7:2030301 MAD1L1 -0.46 -7.72 -0.39 1.32e-13 Bipolar disorder and schizophrenia; LIHC cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg21951975 chr1:209979733 IRF6 -0.39 -6.2 -0.32 1.61e-9 Monobrow; LIHC cis rs8014204 0.935 rs3742786 chr14:75373011 A/G cg08847533 chr14:75593920 NEK9 -0.38 -6.4 -0.33 5.15e-10 Caffeine consumption; LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04335562 chr19:2945000 ZNF77 0.49 6.9 0.35 2.53e-11 Lung function (FEV1/FVC); LIHC cis rs2797685 1.000 rs707466 chr1:7861600 C/A cg04725166 chr1:7887271 PER3 -0.4 -7.12 -0.36 6.46e-12 Crohn's disease; LIHC cis rs1801251 0.896 rs7573208 chr2:233696701 C/A cg25237894 chr2:233734115 C2orf82 -0.54 -10.38 -0.49 4.12e-22 Coronary artery disease; LIHC cis rs9325144 0.647 rs12830095 chr12:38864199 C/T cg26384229 chr12:38710491 ALG10B -0.56 -7.58 -0.38 3.24e-13 Morning vs. evening chronotype; LIHC cis rs10744422 1.000 rs3852537 chr12:123361501 T/C cg25930673 chr12:123319894 HIP1R -0.89 -11.7 -0.53 8.16e-27 Schizophrenia; LIHC cis rs912057 0.601 rs1294413 chr6:6739924 C/A cg06612196 chr6:6737390 NA 0.55 10.16 0.48 2.32e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs7116495 0.609 rs949323 chr11:71714528 T/G cg26138937 chr11:71823887 C11orf51 -1.25 -10.59 -0.5 7.2e-23 Severe influenza A (H1N1) infection; LIHC cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.11e-8 Bipolar disorder; LIHC cis rs13191362 1.000 rs35126854 chr6:163012443 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.58 5.75 0.3 1.96e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs765787 0.530 rs4775836 chr15:45537664 T/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg17372223 chr3:52568218 NT5DC2 0.36 5.78 0.3 1.7e-8 Intelligence (multi-trait analysis); LIHC cis rs4803468 0.935 rs12602 chr19:41889748 T/C cg14132834 chr19:41945861 ATP5SL -0.41 -5.94 -0.31 6.99e-9 Height; LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg02290350 chr8:58132656 NA 0.38 7.79 0.39 8.16e-14 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.565 rs34304022 chr21:40579619 G/A cg11644478 chr21:40555479 PSMG1 0.7 6.42 0.33 4.62e-10 Cognitive function; LIHC cis rs1046896 0.739 rs28459016 chr17:80741194 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.53 8.17 0.4 6.17e-15 Glycated hemoglobin levels; LIHC cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.04 0.31 4.08e-9 Menopause (age at onset); LIHC cis rs250677 0.687 rs250678 chr5:148434830 C/T cg12140854 chr5:148520817 ABLIM3 -0.45 -6.1 -0.31 2.85e-9 Breast cancer; LIHC cis rs67311347 1.000 rs4974017 chr3:40473519 C/T cg18306943 chr3:40428807 ENTPD3 0.33 5.88 0.3 9.6e-9 Renal cell carcinoma; LIHC cis rs797680 0.856 rs6680107 chr1:93770880 G/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.97 -0.31 5.84e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs921968 0.678 rs660432 chr2:219432127 C/T cg02985541 chr2:219472218 PLCD4 0.44 8.35 0.41 1.7e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs8017423 0.967 rs7155315 chr14:90700787 G/A cg04374321 chr14:90722782 PSMC1 0.75 14.45 0.62 2.74e-37 Mortality in heart failure; LIHC cis rs8084351 0.539 rs6508193 chr18:50584544 A/G cg24270629 chr18:50823537 DCC 0.45 6.89 0.35 2.62e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs1075232 1.000 rs66581165 chr15:31743767 A/G cg01030201 chr15:31746330 NA -0.8 -6.32 -0.32 8.37e-10 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg22800045 chr5:56110881 MAP3K1 0.67 8.46 0.42 8.07e-16 Initial pursuit acceleration; LIHC cis rs7903847 0.642 rs7092350 chr10:99140218 A/T cg06359132 chr10:99160096 RRP12 -0.4 -6.37 -0.33 6.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1707322 1.000 rs10890360 chr1:46338444 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7208859 0.623 rs7208088 chr17:29143667 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10791097 0.694 rs10894273 chr11:130742155 G/T cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2334880 0.678 rs12444714 chr16:71452606 C/T cg06353428 chr16:71660113 MARVELD3 -0.86 -8.15 -0.4 6.78e-15 Malaria; LIHC cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg06238570 chr21:40685208 BRWD1 0.48 7.7 0.38 1.52e-13 Cognitive function; LIHC cis rs782590 0.967 rs6545506 chr2:55798108 A/G cg18811423 chr2:55921094 PNPT1 -0.94 -15.69 -0.65 3.5e-42 Metabolic syndrome; LIHC cis rs16828019 0.852 rs12408956 chr1:41651952 G/A cg03387723 chr1:41708464 SCMH1 -0.45 -7.23 -0.36 3.13e-12 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg11494091 chr17:61959527 GH2 0.46 8.31 0.41 2.24e-15 Prudent dietary pattern; LIHC cis rs10791097 0.608 rs12363140 chr11:130744268 A/C cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs916888 0.821 rs70600 chr17:44860021 C/T cg07870213 chr5:140052090 DND1 1.03 10.42 0.49 2.85e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2224391 1.000 rs2753247 chr6:5261987 A/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs3790844 0.667 rs3790843 chr1:200010824 A/G cg13229857 chr1:200006247 NR5A2 -0.41 -6.84 -0.35 3.57e-11 Pancreatic cancer; LIHC cis rs10847980 0.590 rs75794148 chr12:123287329 C/G cg07706471 chr12:123319906 HIP1R 0.75 8.16 0.4 6.55e-15 Adiponectin levels; LIHC cis rs61677309 0.964 rs56020103 chr11:118172132 C/T cg06090739 chr11:118230722 UBE4A 0.34 6.32 0.32 8.33e-10 Lung cancer in ever smokers; LIHC cis rs2836950 0.520 rs59916147 chr21:40634702 T/G cg11890956 chr21:40555474 PSMG1 -0.43 -6.91 -0.35 2.44e-11 Menarche (age at onset); LIHC cis rs9611519 0.929 rs73174657 chr22:41434158 G/A cg03806693 chr22:41940476 POLR3H -0.69 -7.78 -0.39 8.93e-14 Neuroticism; LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg24209194 chr3:40518798 ZNF619 0.64 9.61 0.46 1.66e-19 Renal cell carcinoma; LIHC cis rs1055129 0.560 rs2305913 chr17:73922941 T/C cg19302996 chr17:73780495 UNK -0.46 -6.52 -0.33 2.57e-10 White matter hyperintensity burden; LIHC cis rs9303401 0.659 rs12946397 chr17:56769979 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs1865721 0.958 rs72977878 chr18:73193037 T/G cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.17e-13 Intelligence; LIHC cis rs3762637 0.941 rs6788746 chr3:122106743 G/A cg24169773 chr3:122142474 KPNA1 -0.47 -9.23 -0.45 2.87e-18 LDL cholesterol levels; LIHC cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4727027 0.866 rs2373437 chr7:148779032 T/C cg23583168 chr7:148888333 NA -0.66 -9.29 -0.45 1.89e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7223966 1.000 rs8067064 chr17:61825984 A/C cg05941027 chr17:61774174 LIMD2 0.35 7.43 0.37 8.8e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3018712 0.532 rs55761963 chr11:68402629 G/T cg16797656 chr11:68205561 LRP5 0.5 6.22 0.32 1.45e-9 Total body bone mineral density; LIHC cis rs208520 0.690 rs2144081 chr6:66824972 G/A cg07460842 chr6:66804631 NA -0.76 -8.38 -0.41 1.42e-15 Exhaled nitric oxide output; LIHC cis rs35110281 0.806 rs1454649 chr21:45032982 C/T cg21573476 chr21:45109991 RRP1B -0.57 -10.83 -0.51 1.04e-23 Mean corpuscular volume; LIHC cis rs250677 0.687 rs168750 chr5:148446756 A/G cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs2836974 0.644 rs11088471 chr21:40699313 A/G cg17971929 chr21:40555470 PSMG1 -0.42 -6.26 -0.32 1.16e-9 Cognitive function; LIHC cis rs7249142 0.562 rs2314035 chr19:19284920 T/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.12 -0.31 2.6e-9 IgG glycosylation; LIHC cis rs1552244 0.554 rs2272118 chr3:10049287 T/C cg21531657 chr3:10005747 TMEM111 0.39 5.72 0.3 2.28e-8 Alzheimer's disease; LIHC cis rs7582720 1.000 rs114123510 chr2:203831212 T/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs12497850 0.797 rs61583136 chr3:49189195 C/T cg07636037 chr3:49044803 WDR6 0.88 15.46 0.64 2.85e-41 Parkinson's disease; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg02016892 chr7:22122612 NA -0.52 -6.24 -0.32 1.3e-9 Lung function (FEV1); LIHC trans rs881375 0.678 rs2416804 chr9:123676396 C/G cg01530962 chr3:9027157 SRGAP3 0.35 6.07 0.31 3.33e-9 Rheumatoid arthritis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23088989 chr10:38301786 ZNF33A 0.42 6.29 0.32 9.48e-10 Longevity; LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs3018712 0.532 rs2510399 chr11:68421458 A/G cg16797656 chr11:68205561 LRP5 -0.44 -5.81 -0.3 1.41e-8 Total body bone mineral density; LIHC cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg12373951 chr3:133503437 NA 0.47 7.88 0.39 4.54e-14 Iron status biomarkers; LIHC cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg12756686 chr19:29218302 NA 0.44 6.78 0.34 5.13e-11 Methadone dose in opioid dependence; LIHC trans rs875971 0.965 rs7794930 chr7:65778546 A/C cg10756647 chr7:56101905 PSPH -0.44 -6.38 -0.33 5.64e-10 Aortic root size; LIHC cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg17747265 chr1:1875780 NA -0.59 -11.11 -0.51 1.12e-24 Body mass index; LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg14709524 chr16:89940631 TCF25 0.52 7.08 0.36 8.05e-12 Skin colour saturation; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs912330 0.529 rs4772100 chr13:99196573 G/T cg07423050 chr13:99094983 FARP1 -0.38 -6.78 -0.34 5.17e-11 Alzheimer's disease; LIHC trans rs4843747 0.671 rs28671027 chr16:88116323 G/A cg26811252 chr16:29126840 RRN3P2 0.41 6.82 0.35 4.14e-11 Menopause (age at onset); LIHC cis rs7408868 0.908 rs10416865 chr19:15277601 T/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.89 -0.3 9.39e-9 Pulse pressure; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg26338869 chr17:61819248 STRADA -0.61 -8.82 -0.43 5.75e-17 Prudent dietary pattern; LIHC cis rs7546668 0.947 rs10803391 chr1:15876578 A/G cg11706911 chr1:15910989 AGMAT 0.44 6.71 0.34 8.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs4925386 0.681 rs2427295 chr20:60927431 G/A cg24112000 chr20:60950667 NA -0.45 -6.03 -0.31 4.23e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs4555082 0.957 rs2816627 chr14:105736109 A/G cg10792982 chr14:105748885 BRF1 0.44 6.12 0.31 2.5e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs7149337 0.805 rs2999357 chr14:51606001 C/G cg23942311 chr14:51606299 NA 0.36 7.37 0.37 1.31e-12 Cancer; LIHC cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg08975724 chr8:8085496 FLJ10661 -0.38 -6.25 -0.32 1.2e-9 Mood instability; LIHC cis rs2463822 1.000 rs7481995 chr11:62129312 G/C cg06239285 chr11:62104954 ASRGL1 0.91 6.85 0.35 3.55e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs7772486 0.875 rs2474353 chr6:146323883 G/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.27 -0.32 1.12e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.546 rs4425043 chr2:27733452 G/A cg21747090 chr2:27597821 SNX17 -0.41 -5.97 -0.31 6e-9 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03383553 chr7:5349072 TNRC18 0.42 6.15 0.32 2.14e-9 Pancreatic cancer; LIHC cis rs17094222 0.812 rs10883519 chr10:102435648 T/C cg26540559 chr10:102447443 NA 0.32 6.17 0.32 1.96e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4474465 0.688 rs4277140 chr11:78285096 G/T cg02023728 chr11:77925099 USP35 0.34 6.18 0.32 1.83e-9 Alzheimer's disease (survival time); LIHC cis rs9430161 0.579 rs7542158 chr1:11040193 G/A cg02454025 chr1:11042201 C1orf127 0.74 13.42 0.59 2.89e-33 Ewing sarcoma; LIHC cis rs6964587 0.620 rs6967588 chr7:91643402 G/T cg17063962 chr7:91808500 NA 0.63 11.29 0.52 2.48e-25 Breast cancer; LIHC cis rs7267979 1.000 rs2424704 chr20:25273929 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.48 7.04 0.36 1.07e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7903847 0.642 rs10882914 chr10:99142057 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12079745 0.793 rs12094791 chr1:169387911 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.8 -7.11 -0.36 7e-12 QT interval; LIHC cis rs12286929 0.556 rs11605461 chr11:115053011 C/T cg04055981 chr11:115044050 NA -0.5 -8.15 -0.4 6.92e-15 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1348850 1.000 rs1348850 chr2:178418575 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.78 11.58 0.53 2.19e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04688917 chr3:179040469 ZNF639 0.43 6.6 0.34 1.58e-10 Pancreatic cancer; LIHC cis rs7917772 0.565 rs1043450 chr10:104434209 A/G cg22532475 chr10:104410764 TRIM8 -0.41 -7.21 -0.36 3.58e-12 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs611744 0.870 rs635941 chr8:109235457 G/A cg18478394 chr8:109455254 TTC35 0.37 6.16 0.32 1.99e-9 Dupuytren's disease; LIHC cis rs7223966 1.000 rs992416 chr17:61745905 A/C cg05941027 chr17:61774174 LIMD2 0.33 6.71 0.34 8.24e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs11785400 1.000 rs4266629 chr8:143736635 A/G cg24634471 chr8:143751801 JRK 0.51 8.28 0.41 2.72e-15 Schizophrenia; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.09 0.55 3.01e-28 Prudent dietary pattern; LIHC cis rs7246657 0.943 rs12981532 chr19:37889280 G/A cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs3740540 0.530 rs10751598 chr10:126290951 A/G cg04949429 chr10:126290192 LHPP -0.44 -7.29 -0.37 2.22e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg07308232 chr7:1071921 C7orf50 -0.52 -8.47 -0.42 7.51e-16 Longevity;Endometriosis; LIHC cis rs950776 0.518 rs62008194 chr15:78813805 G/T cg22563815 chr15:78856949 CHRNA5 0.35 6.4 0.33 5.07e-10 Sudden cardiac arrest; LIHC cis rs7412746 0.611 rs11204748 chr1:150927369 G/T cg15448220 chr1:150897856 SETDB1 0.39 6.18 0.32 1.78e-9 Melanoma; LIHC cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg25072359 chr17:41440525 NA 0.38 6.03 0.31 4.34e-9 Menopause (age at onset); LIHC cis rs7107174 0.901 rs2512522 chr11:77925855 G/C cg02023728 chr11:77925099 USP35 0.52 9.81 0.47 3.46e-20 Testicular germ cell tumor; LIHC cis rs7044106 0.537 rs10739573 chr9:123489818 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.48 6.9 0.35 2.57e-11 Hip circumference adjusted for BMI; LIHC trans rs1464321 1.000 rs1464321 chr12:103656233 A/C cg15403093 chr12:133312361 ANKLE2 0.38 6.05 0.31 3.78e-9 Body mass index; LIHC cis rs2274273 0.905 rs2147961 chr14:55585381 T/C cg01864836 chr14:55583639 NA -0.44 -8.65 -0.42 2.05e-16 Protein biomarker; LIHC cis rs10208940 0.502 rs10203846 chr2:68670921 G/A cg12452813 chr2:68675892 NA -0.71 -8.18 -0.4 5.77e-15 Urate levels in lean individuals; LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs7937890 0.559 rs2597196 chr11:14491601 C/T cg02886208 chr11:14281011 SPON1 0.44 6.13 0.31 2.44e-9 Mitochondrial DNA levels; LIHC cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg14983838 chr19:29218262 NA 0.48 7.46 0.37 7.4e-13 Methadone dose in opioid dependence; LIHC cis rs12701220 0.655 rs34344742 chr7:1149288 C/G cg04498913 chr7:1135747 C7orf50 0.44 6.98 0.35 1.51e-11 Bronchopulmonary dysplasia; LIHC cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg19045956 chr2:200819837 C2orf60;C2orf47 0.33 5.79 0.3 1.61e-8 Osteoporosis; LIHC cis rs826838 1.000 rs1095575 chr12:39110284 C/G cg26384229 chr12:38710491 ALG10B -0.55 -8.24 -0.41 3.62e-15 Heart rate; LIHC trans rs875971 0.545 rs316323 chr7:65610989 C/T cg26939375 chr7:64535504 NA -0.41 -6.47 -0.33 3.32e-10 Aortic root size; LIHC cis rs13191362 1.000 rs35754151 chr6:163074867 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.75 6.53 0.33 2.44e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2274273 0.901 rs7147136 chr14:55826688 G/C cg01864836 chr14:55583639 NA -0.38 -6.58 -0.34 1.72e-10 Protein biomarker; LIHC cis rs7107174 0.681 rs881337 chr11:78128335 G/C cg02023728 chr11:77925099 USP35 0.41 7.37 0.37 1.33e-12 Testicular germ cell tumor; LIHC cis rs933688 0.532 rs10072084 chr5:90539203 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.44 7.3 0.37 1.97e-12 Smoking behavior; LIHC cis rs9859260 0.744 rs3933 chr3:195784997 C/T cg03462622 chr3:195777018 TFRC -0.33 -5.71 -0.3 2.4e-8 Mean corpuscular volume; LIHC cis rs7659604 0.521 rs4833773 chr4:122689245 C/T cg19671926 chr4:122722719 EXOSC9 0.54 8.32 0.41 2.15e-15 Type 2 diabetes; LIHC cis rs1371867 0.875 rs1788184 chr8:101335106 A/G cg06636551 chr8:101224915 SPAG1 -0.47 -8.72 -0.43 1.26e-16 Atrioventricular conduction; LIHC cis rs1552244 0.554 rs34883592 chr3:10046165 C/T cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs311392 0.525 rs311391 chr8:55103542 T/G cg20636351 chr8:55087400 NA -0.34 -7.1 -0.36 7.46e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs7534824 0.625 rs2391574 chr1:101373298 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 6.61 0.34 1.52e-10 Refractive astigmatism; LIHC cis rs3806843 0.648 rs2530233 chr5:140082876 A/G cg16179182 chr5:140090404 VTRNA1-1 0.37 6.08 0.31 3.24e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9916302 0.731 rs11868030 chr17:37650332 A/G cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC cis rs6964587 1.000 rs7789492 chr7:91668854 C/T cg17063962 chr7:91808500 NA 1.03 20.91 0.75 3.97e-63 Breast cancer; LIHC cis rs2180341 1.000 rs6569478 chr6:127598619 G/A cg27446573 chr6:127587934 RNF146 1.0 15.32 0.64 1.06e-40 Breast cancer; LIHC trans rs7668874 0.779 rs7688219 chr4:116814062 T/C cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs2576037 0.501 rs557661 chr18:44365657 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.62 9.58 0.46 2.09e-19 Personality dimensions; LIHC cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.9 0.3 8.95e-9 Menopause (age at onset); LIHC cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg03806693 chr22:41940476 POLR3H -0.95 -10.95 -0.51 4.14e-24 Vitiligo; LIHC cis rs8180040 0.966 rs2101247 chr3:47494303 G/A cg27129171 chr3:47204927 SETD2 -0.56 -9.39 -0.45 8.75e-19 Colorectal cancer; LIHC trans rs2262909 0.889 rs61268244 chr19:22310130 C/T cg17074339 chr11:11642133 GALNTL4 0.47 7.38 0.37 1.25e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs7131987 1.000 rs7131987 chr12:29406488 G/T cg16970926 chr12:29381810 FAR2 0.31 6.71 0.34 8.23e-11 QT interval; LIHC cis rs597539 0.654 rs619727 chr11:68627535 A/G cg06028808 chr11:68637592 NA 0.46 6.24 0.32 1.33e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.07 0.31 3.47e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2153535 0.580 rs1414349 chr6:8472290 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs2115630 1.000 rs1030863 chr15:85282635 C/T cg12501888 chr15:85177176 SCAND2 -0.5 -7.79 -0.39 7.99e-14 P wave terminal force; LIHC cis rs9790314 1.000 rs459697 chr3:161093420 G/A cg04691961 chr3:161091175 C3orf57 -0.43 -6.86 -0.35 3.17e-11 Morning vs. evening chronotype; LIHC cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg13877915 chr19:58951672 ZNF132 0.63 10.74 0.5 2.31e-23 Uric acid clearance; LIHC cis rs5753618 0.561 rs2283879 chr22:31638448 G/A cg07713946 chr22:31675144 LIMK2 -0.43 -7.81 -0.39 7.12e-14 Colorectal cancer; LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg14893161 chr1:205819251 PM20D1 -0.67 -9.77 -0.47 4.87e-20 Menarche (age at onset); LIHC cis rs3008870 1.000 rs2065000 chr1:67468124 G/C cg08660285 chr1:67390436 MIER1;WDR78 -0.93 -16.06 -0.66 1.26e-43 Lymphocyte percentage of white cells; LIHC cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6089584 0.927 rs1886007 chr20:60581049 G/A cg06108461 chr20:60628389 TAF4 -0.89 -13.72 -0.6 1.87e-34 Body mass index; LIHC cis rs9733 0.596 rs12086472 chr1:150697710 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg24693881 chr1:107596107 NA -0.53 -9.13 -0.44 6.24e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7224737 1.000 rs12603327 chr17:40290552 T/C cg20291162 chr17:40259547 DHX58 -0.4 -6.38 -0.33 5.82e-10 Fibrinogen levels; LIHC cis rs15676 0.783 rs10988121 chr9:131564926 A/T cg00228799 chr9:131580591 ENDOG -0.48 -6.8 -0.34 4.79e-11 Blood metabolite levels; LIHC cis rs9911578 1.000 rs2270097 chr17:56572070 G/A cg05425664 chr17:57184151 TRIM37 0.58 8.54 0.42 4.32e-16 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg17971929 chr21:40555470 PSMG1 0.83 10.09 0.48 4.04e-21 Cognitive function; LIHC cis rs8103278 1.000 rs1548029 chr19:46309203 A/C cg02376097 chr19:46275166 DMPK -0.44 -6.88 -0.35 2.87e-11 Coronary artery disease; LIHC cis rs6964587 0.605 rs6956022 chr7:91553199 A/G cg17063962 chr7:91808500 NA -0.62 -11.21 -0.52 4.59e-25 Breast cancer; LIHC trans rs35110281 0.616 rs2236666 chr21:45109856 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.49 6.4 0.33 5.23e-10 Mean corpuscular volume; LIHC cis rs2717559 0.542 rs2717590 chr8:143900712 A/G cg07661805 chr8:143867942 LY6D -0.27 -5.92 -0.3 7.8e-9 Urinary tract infection frequency; LIHC cis rs1707322 1.000 rs12097761 chr1:46291162 T/C cg06784218 chr1:46089804 CCDC17 0.38 6.7 0.34 8.73e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs11098499 0.954 rs9685777 chr4:120365965 C/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs7617480 0.648 rs7653408 chr3:48972351 A/C cg07636037 chr3:49044803 WDR6 0.74 9.04 0.44 1.17e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs16854884 0.632 rs60505453 chr3:143643864 C/G cg06585982 chr3:143692056 C3orf58 0.63 8.79 0.43 7.66e-17 Economic and political preferences (feminism/equality); LIHC cis rs6570726 0.935 rs409121 chr6:145839793 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2380220 0.576 rs7751219 chr6:96018915 G/A cg23517279 chr6:96025343 MANEA 0.57 5.78 0.3 1.68e-8 Behavioural disinhibition (generation interaction); LIHC cis rs4700695 0.614 rs446618 chr5:65210062 G/A cg21114390 chr5:65439923 SFRS12 0.46 5.83 0.3 1.3e-8 Facial morphology (factor 19); LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs1728785 0.901 rs11642189 chr16:68583990 G/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs7674212 0.570 rs2251634 chr4:104082349 C/T cg16532752 chr4:104119610 CENPE -0.46 -7.39 -0.37 1.11e-12 Type 2 diabetes; LIHC cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg10295955 chr4:187884368 NA -0.98 -22.77 -0.78 1.69e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.863 rs2170276 chr4:120485824 A/C cg09307838 chr4:120376055 NA 0.75 11.33 0.52 1.79e-25 Corneal astigmatism; LIHC trans rs875971 0.545 rs7787063 chr7:65628999 G/A cg26939375 chr7:64535504 NA 0.41 6.51 0.33 2.63e-10 Aortic root size; LIHC cis rs11718455 0.960 rs11720974 chr3:43999111 G/C cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC trans rs1814175 0.715 rs1722007 chr11:49897319 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg25533220 chr19:2328480 SPPL2B;LSM7 -0.46 -6.05 -0.31 3.8e-9 Facial morphology (factor 20); LIHC cis rs2066819 1.000 rs57137641 chr12:56741228 G/A cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs4631830 0.900 rs7075009 chr10:51544143 T/G cg20129853 chr10:51489980 NA -0.41 -8.93 -0.43 2.64e-17 Prostate-specific antigen levels; LIHC cis rs903552 1.000 rs4965386 chr15:102003207 G/A cg00659931 chr15:102010125 PCSK6 -0.45 -6.15 -0.32 2.2e-9 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16439512 chr15:57598924 LOC283663 0.44 6.22 0.32 1.48e-9 Lung function (FEV1/FVC); LIHC cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg13047869 chr3:10149882 C3orf24 0.56 7.03 0.36 1.15e-11 Alzheimer's disease; LIHC cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs2991971 0.729 rs10890328 chr1:45905383 G/T cg24296786 chr1:45957014 TESK2 -0.53 -8.05 -0.4 1.43e-14 High light scatter reticulocyte count; LIHC trans rs11098499 0.863 rs1010740 chr4:120463409 C/T cg25214090 chr10:38739885 LOC399744 -0.57 -9.03 -0.44 1.3e-17 Corneal astigmatism; LIHC cis rs1003719 0.715 rs2835642 chr21:38539066 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18573204 chr11:798458 NA -0.5 -6.22 -0.32 1.49e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1005277 0.522 rs289647 chr10:37968278 A/G cg00409905 chr10:38381863 ZNF37A -0.54 -9.31 -0.45 1.62e-18 Extrinsic epigenetic age acceleration; LIHC cis rs7523273 0.606 rs10449303 chr1:207961058 A/G cg22525895 chr1:207977042 MIR29B2 -0.65 -10.52 -0.49 1.34e-22 Schizophrenia; LIHC cis rs12928939 0.815 rs11648483 chr16:71707398 T/C cg03805757 chr16:71968109 PKD1L3 -0.67 -7.66 -0.38 1.97e-13 Post bronchodilator FEV1; LIHC trans rs7246657 0.943 rs7248733 chr19:37996361 A/C cg10208301 chr11:6592745 DNHD1 0.45 6.42 0.33 4.58e-10 Coronary artery calcification; LIHC trans rs1005277 0.579 rs2474572 chr10:38385316 A/G cg23533926 chr12:111358616 MYL2 -0.33 -6.37 -0.33 6.02e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6754311 0.731 rs892715 chr2:136576577 T/C cg07305463 chr2:136567211 LCT 0.39 7.54 0.38 4.34e-13 Mosquito bite size; LIHC cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 11.55 0.53 2.78e-26 Platelet count; LIHC cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg01069141 chr11:67398826 TBX10;NUDT8 0.38 6.73 0.34 7.22e-11 Mean corpuscular volume; LIHC cis rs2797160 0.967 rs1343120 chr6:125992810 A/G cg05901451 chr6:126070800 HEY2 -0.4 -6.77 -0.34 5.66e-11 Endometrial cancer; LIHC cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg16680214 chr1:154839983 KCNN3 -0.34 -5.89 -0.3 9.24e-9 Prostate cancer; LIHC cis rs1862618 0.671 rs173763 chr5:56225418 G/A cg12311346 chr5:56204834 C5orf35 -0.46 -6.27 -0.32 1.09e-9 Initial pursuit acceleration; LIHC cis rs78545713 0.536 rs116337444 chr6:26208269 G/A cg16070018 chr6:26224392 HIST1H3E 0.8 7.54 0.38 4.2e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs11690935 0.959 rs10184866 chr2:172608956 T/G cg13550731 chr2:172543902 DYNC1I2 -0.95 -19.26 -0.72 1.68e-56 Schizophrenia; LIHC cis rs921968 0.540 rs10190250 chr2:219457731 C/T cg02176678 chr2:219576539 TTLL4 -0.55 -7.6 -0.38 2.81e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7551222 0.752 rs12032733 chr1:204481209 G/A cg20240347 chr1:204465584 NA -0.35 -7.42 -0.37 9.64e-13 Schizophrenia; LIHC cis rs7927592 0.830 rs10896339 chr11:68302846 G/C cg20283391 chr11:68216788 NA -0.53 -8.11 -0.4 9.35e-15 Total body bone mineral density; LIHC trans rs875971 0.545 rs12671152 chr7:65776127 G/T cg26939375 chr7:64535504 NA 0.41 6.15 0.32 2.15e-9 Aortic root size; LIHC cis rs7044106 0.708 rs991121 chr9:123370345 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.81 0.39 6.88e-14 Hip circumference adjusted for BMI; LIHC cis rs4407350 0.870 rs5765712 chr22:44914711 A/G cg26276947 chr22:44892394 LDOC1L 0.34 6.39 0.33 5.35e-10 Intelligence (multi-trait analysis); LIHC cis rs7582720 0.945 rs72936875 chr2:203791912 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03260790 chr12:56211718 ORMDL2;SARNP 0.5 7.5 0.38 5.65e-13 Pancreatic cancer; LIHC cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg05552183 chr6:42928497 GNMT 0.68 10.29 0.49 8.11e-22 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs11098499 0.863 rs12498539 chr4:120468370 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.41 0.45 7.58e-19 Corneal astigmatism; LIHC cis rs7474896 0.537 rs598857 chr10:38302926 A/G cg25427524 chr10:38739819 LOC399744 0.45 5.9 0.3 8.53e-9 Obesity (extreme); LIHC cis rs4718428 1.000 rs1830070 chr7:66349671 T/C cg11764359 chr7:65958608 NA 0.5 6.65 0.34 1.19e-10 Corneal structure; LIHC trans rs6951245 0.554 rs4724294 chr7:1139695 G/A cg13565492 chr6:43139072 SRF -0.79 -7.32 -0.37 1.81e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1843834 0.721 rs1601730 chr2:225590153 G/A cg22509189 chr2:225307070 NA -0.53 -6.35 -0.32 6.96e-10 IgE levels in asthmatics (D.p. specific); LIHC cis rs17253792 0.822 rs10083493 chr14:56045411 C/T cg24579896 chr14:56047964 C14orf33;KTN1 0.7 5.82 0.3 1.38e-8 Putamen volume; LIHC cis rs10489202 0.913 rs380753 chr1:168035273 G/T cg24449463 chr1:168025552 DCAF6 -0.57 -8.19 -0.41 5.19e-15 Schizophrenia; LIHC cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg13271783 chr10:134563150 INPP5A -0.6 -7.22 -0.36 3.32e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3008870 0.959 rs2815353 chr1:67483372 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.93 15.91 0.65 4.79e-43 Lymphocyte percentage of white cells; LIHC cis rs7107174 0.711 rs66583694 chr11:78037773 C/T cg02023728 chr11:77925099 USP35 0.45 8.83 0.43 5.37e-17 Testicular germ cell tumor; LIHC cis rs10744422 1.000 rs7139055 chr12:123364198 A/G cg07706471 chr12:123319906 HIP1R 0.58 7.32 0.37 1.79e-12 Schizophrenia; LIHC trans rs1814175 0.645 rs847627 chr11:49927177 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs10751667 0.961 rs6597971 chr11:928598 T/A cg06064525 chr11:970664 AP2A2 -0.48 -12.05 -0.55 3.99e-28 Alzheimer's disease (late onset); LIHC cis rs12079745 0.793 rs10800445 chr1:169374793 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.96 -0.35 1.74e-11 QT interval; LIHC cis rs11077998 0.967 rs60488670 chr17:80522667 T/C cg10255544 chr17:80519551 FOXK2 0.49 8.84 0.43 5.32e-17 Reticulocyte fraction of red cells; LIHC cis rs2404602 0.647 rs11632765 chr15:76974261 A/T cg23625390 chr15:77176239 SCAPER 0.56 9.43 0.45 6.19e-19 Blood metabolite levels; LIHC cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg27572855 chr1:25598939 RHD 0.4 8.61 0.42 2.66e-16 Erythrocyte sedimentation rate; LIHC cis rs2153535 0.580 rs6920779 chr6:8437624 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.85 0.39 5.3e-14 Motion sickness; LIHC cis rs10242455 0.571 rs11734 chr7:99229768 C/G cg18809830 chr7:99032528 PTCD1 0.71 5.99 0.31 5.37e-9 Blood metabolite levels; LIHC cis rs12497850 0.897 rs6795025 chr3:49081247 T/C cg06212747 chr3:49208901 KLHDC8B 0.59 7.56 0.38 3.72e-13 Parkinson's disease; LIHC cis rs5753037 0.653 rs131272 chr22:30153655 A/G cg01021169 chr22:30184971 ASCC2 -0.31 -5.75 -0.3 1.96e-8 Type 1 diabetes; LIHC cis rs3784262 1.000 rs12915901 chr15:58279432 G/A cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.37 -0.33 5.97e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6597981 0.592 rs10902218 chr11:743813 C/T cg21775979 chr11:780331 NA 0.55 9.06 0.44 9.99e-18 Breast cancer; LIHC cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg03264133 chr6:25882463 NA -0.71 -8.83 -0.43 5.7e-17 Intelligence (multi-trait analysis); LIHC cis rs16958440 0.867 rs78720782 chr18:44664015 A/T cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs2839186 0.706 rs2839188 chr21:47692798 C/T cg13126279 chr21:47581558 C21orf56 -0.4 -5.91 -0.3 8.11e-9 Testicular germ cell tumor; LIHC cis rs4474465 0.850 rs4944205 chr11:78227790 T/A cg27205649 chr11:78285834 NARS2 0.39 5.96 0.31 6.31e-9 Alzheimer's disease (survival time); LIHC cis rs7546094 0.509 rs7415988 chr1:113159730 G/T cg22162597 chr1:113214053 CAPZA1 -0.72 -9.64 -0.46 1.33e-19 Platelet distribution width; LIHC cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg27297192 chr10:134578999 INPP5A 0.55 7.7 0.38 1.52e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs11098499 0.863 rs12508173 chr4:120318526 T/C cg25214090 chr10:38739885 LOC399744 0.6 9.72 0.47 7.01e-20 Corneal astigmatism; LIHC cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg12463550 chr7:65579703 CRCP -0.66 -6.85 -0.35 3.41e-11 Diabetic kidney disease; LIHC cis rs16828019 0.929 rs35813191 chr1:41742800 T/C cg03387723 chr1:41708464 SCMH1 -0.44 -7.06 -0.36 9.06e-12 Intelligence (multi-trait analysis); LIHC cis rs6598955 0.640 rs4233460 chr1:26633387 A/G cg00852783 chr1:26633632 UBXN11 0.53 8.78 0.43 7.99e-17 Obesity-related traits; LIHC cis rs9611519 0.894 rs13053242 chr22:41459486 G/A cg06634786 chr22:41940651 POLR3H -0.52 -5.73 -0.3 2.26e-8 Neuroticism; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg01032570 chr8:22224534 SLC39A14 -0.46 -6.36 -0.33 6.4e-10 Monocyte count; LIHC cis rs6570726 0.764 rs9403726 chr6:145901686 G/T cg23711669 chr6:146136114 FBXO30 0.64 10.93 0.51 4.64e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs11190604 1.000 rs11190601 chr10:102296730 A/G cg07080220 chr10:102295463 HIF1AN 0.53 7.56 0.38 3.75e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs561341 0.609 rs7209493 chr17:30197323 A/G cg13647721 chr17:30228624 UTP6 -0.65 -6.81 -0.35 4.46e-11 Hip circumference adjusted for BMI; LIHC cis rs600806 0.676 rs2781553 chr1:110026989 G/T cg08911820 chr1:110026001 ATXN7L2 0.55 6.59 0.34 1.7e-10 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.931 rs11211189 chr1:46261584 A/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.98 0.31 5.65e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6546550 0.867 rs4401231 chr2:70063563 G/C cg02498382 chr2:70120550 SNRNP27 -0.39 -6.49 -0.33 3.03e-10 Prevalent atrial fibrillation; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03578013 chr3:24145718 LOC152024 -0.4 -6.5 -0.33 2.86e-10 Systolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19280121 chr17:21117780 TMEM11 0.4 6.32 0.32 8.29e-10 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25887850 chr20:44509743 ZSWIM1 0.48 6.66 0.34 1.07e-10 Pancreatic cancer; LIHC cis rs875971 0.545 rs1796226 chr7:66087710 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.34 6.88 0.35 2.9100000000000002e-11 Aortic root size; LIHC cis rs611744 0.659 rs669584 chr8:109138107 G/A cg21045802 chr8:109455806 TTC35 0.51 8.59 0.42 3.15e-16 Dupuytren's disease; LIHC cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3096299 0.582 rs12935119 chr16:89542874 A/T cg02034447 chr16:89574710 SPG7 0.38 5.83 0.3 1.29e-8 Multiple myeloma (IgH translocation); LIHC cis rs7546668 1.000 rs10803394 chr1:15909480 G/C cg11706911 chr1:15910989 AGMAT 0.47 7.16 0.36 4.97e-12 Glomerular filtration rate (creatinine); LIHC cis rs11792861 0.926 rs1333344 chr9:111776224 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.63 0.42 2.31e-16 Menarche (age at onset); LIHC cis rs10193935 0.901 rs13429697 chr2:42529818 C/T cg27598129 chr2:42591480 NA -0.7 -10.65 -0.5 4.56e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg11905131 chr22:24372483 LOC391322 -0.7 -10.74 -0.5 2.27e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618501 0.521 rs3733134 chr3:49939503 C/T cg21467203 chr3:49911342 NA -0.59 -10.75 -0.5 1.99e-23 Intelligence (multi-trait analysis); LIHC trans rs7618501 0.573 rs7634917 chr3:50049299 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.59 -9.6 -0.46 1.73e-19 Intelligence (multi-trait analysis); LIHC cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg19723775 chr5:179050963 HNRNPH1 -0.42 -6.58 -0.34 1.81e-10 Lung cancer; LIHC cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.837 rs2838343 chr21:45078035 C/T cg01579765 chr21:45077557 HSF2BP -0.31 -5.92 -0.31 7.64e-9 Mean corpuscular volume; LIHC cis rs10420951 0.617 rs77852139 chr19:18606526 T/G cg10790698 chr19:18539756 SSBP4 -0.42 -5.86 -0.3 1.11e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17376456 0.877 rs7701974 chr5:93311417 C/T cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs7772486 0.686 rs9390348 chr6:146044748 C/T cg23711669 chr6:146136114 FBXO30 -0.64 -11.7 -0.53 8.18e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg05590025 chr7:65112418 INTS4L2 -0.61 -6.78 -0.34 5.22e-11 Diabetic kidney disease; LIHC cis rs10779751 0.960 rs4845988 chr1:11319587 A/G cg08854313 chr1:11322531 MTOR 0.88 15.9 0.65 5.36e-43 Body mass index; LIHC cis rs9464760 0.527 rs13194276 chr6:15158452 G/C cg15799072 chr6:15248335 JARID2 0.59 5.92 0.3 7.97e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs11673344 0.864 rs56208574 chr19:37498745 C/T cg27390819 chr19:37464633 NA -0.51 -6.21 -0.32 1.57e-9 Obesity-related traits; LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg09367891 chr1:107599246 PRMT6 0.7 11.5 0.53 4.21e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2425143 1.000 rs2295356 chr20:34252856 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.89 -0.3 9.45e-9 Blood protein levels; LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg27432699 chr2:27873401 GPN1 -0.49 -6.9 -0.35 2.47e-11 Menopause (age at onset); LIHC trans rs6489882 0.703 rs11066451 chr12:113361443 G/A cg10175203 chr3:128143634 NA 0.4 6.41 0.33 4.85e-10 Chronic lymphocytic leukemia; LIHC cis rs875971 0.545 rs6979636 chr7:65741625 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.38 7.67 0.38 1.78e-13 Aortic root size; LIHC cis rs225245 0.755 rs226441 chr17:34033072 C/T cg05299278 chr17:33885742 SLFN14 0.23 6.23 0.32 1.35e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs959260 1.000 rs2117563 chr17:73368985 A/G cg20590849 chr17:73267439 MIF4GD -0.53 -5.75 -0.3 1.96e-8 Systemic lupus erythematosus; LIHC cis rs6137287 0.668 rs6047258 chr20:21098277 A/C cg04219410 chr20:21106687 PLK1S1 0.34 6.02 0.31 4.43e-9 Height; LIHC cis rs16828019 0.852 rs12408956 chr1:41651952 G/A cg20697417 chr1:41786797 NA 0.35 6.65 0.34 1.15e-10 Intelligence (multi-trait analysis); LIHC cis rs9522267 0.535 rs9515452 chr13:112234553 A/G cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg06618935 chr21:46677482 NA -0.3 -5.76 -0.3 1.92e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1912483 0.505 rs3760372 chr17:45380002 T/C cg08085267 chr17:45401833 C17orf57 -0.56 -7.24 -0.36 3.01e-12 Coronary artery disease; LIHC cis rs13108904 0.901 rs1316393 chr4:1315619 A/G cg13395646 chr4:1353034 KIAA1530 0.68 9.83 0.47 2.93e-20 Obesity-related traits; LIHC cis rs6964587 0.773 rs59242586 chr7:91918145 A/G cg17063962 chr7:91808500 NA 0.97 16.94 0.68 3.52e-47 Breast cancer; LIHC cis rs9818758 0.607 rs34823813 chr3:49749976 G/A cg00383909 chr3:49044727 WDR6 0.94 6.69 0.34 9.3e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7937682 0.855 rs7934922 chr11:111500026 T/C cg09085632 chr11:111637200 PPP2R1B -1.03 -12.24 -0.55 7.9e-29 Primary sclerosing cholangitis; LIHC cis rs11212260 0.512 rs77832235 chr11:107149713 T/C cg25435332 chr11:107328525 CWF19L2 0.73 6.79 0.34 4.93e-11 IgG glycosylation; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg24846343 chr22:24311635 DDTL 0.59 10.66 0.5 4.22e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7208859 0.673 rs2433 chr17:29226228 T/C cg14067834 chr17:29058358 SUZ12P 0.67 6.5 0.33 2.86e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs35110281 0.807 rs4818850 chr21:45028071 T/G cg21573476 chr21:45109991 RRP1B -0.53 -9.99 -0.48 8.99e-21 Mean corpuscular volume; LIHC cis rs34172651 0.917 rs200539 chr16:24735178 T/C cg00339695 chr16:24857497 SLC5A11 -0.56 -8.6 -0.42 2.92e-16 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.521 rs2088526 chr11:49531968 G/A cg18944383 chr4:111397179 ENPEP -0.35 -8.1 -0.4 9.97e-15 Coronary artery disease; LIHC trans rs877282 0.853 rs11596346 chr10:756673 A/T cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs74417235 0.673 rs6873342 chr5:154051835 A/G cg08754654 chr5:154026448 NA -0.32 -7.06 -0.36 9.17e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs7618501 0.633 rs2856234 chr3:50139142 A/G cg24110177 chr3:50126178 RBM5 0.51 8.27 0.41 3.02e-15 Intelligence (multi-trait analysis); LIHC trans rs12249377 0.528 rs11186299 chr10:92513343 C/A cg12165685 chr19:47288109 SLC1A5 -0.53 -6.1 -0.31 2.81e-9 White matter microstructure (global fractional anisotropy); LIHC cis rs8072100 0.905 rs9895274 chr17:45539117 C/T cg08085267 chr17:45401833 C17orf57 -0.57 -8.58 -0.42 3.31e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs244293 0.965 rs244360 chr17:53191703 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.54 -0.38 4.36e-13 Menarche (age at onset); LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs7264396 0.779 rs6087723 chr20:34175783 G/A cg04508476 chr20:34239394 CPNE1;RBM12 0.54 8.56 0.42 3.92e-16 Total cholesterol levels; LIHC cis rs36051895 0.623 rs12720 chr9:5231712 T/A cg02405213 chr9:5042618 JAK2 -0.69 -11.02 -0.51 2.26e-24 Pediatric autoimmune diseases; LIHC cis rs4319547 0.915 rs11058402 chr12:122981053 A/G cg23029597 chr12:123009494 RSRC2 -0.54 -7.7 -0.38 1.5e-13 Body mass index; LIHC cis rs5769765 1.000 rs5770742 chr22:50270309 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13495025 chr9:130230056 LRSAM1 0.46 6.31 0.32 8.56e-10 Hepatitis; LIHC cis rs1003719 0.707 rs9976360 chr21:38587860 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.23 -0.48 1.3e-21 Eye color traits; LIHC cis rs3008870 1.000 rs12039172 chr1:67447450 A/G cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs9611565 1.000 rs5751086 chr22:41768862 C/T cg03806693 chr22:41940476 POLR3H -0.46 -6.37 -0.33 6e-10 Vitiligo; LIHC cis rs11030122 0.702 rs12281293 chr11:3963814 C/T cg18678763 chr11:4115507 RRM1 -0.57 -8.45 -0.42 8.6e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs798554 0.757 rs1182179 chr7:2873648 A/G cg19717773 chr7:2847554 GNA12 -0.42 -6.47 -0.33 3.32e-10 Height; LIHC cis rs916888 0.821 rs199505 chr17:44859410 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1997103 1.000 rs6953494 chr7:55412157 G/A cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg17971929 chr21:40555470 PSMG1 0.85 10.16 0.48 2.26e-21 Cognitive function; LIHC cis rs916888 0.821 rs199512 chr17:44857352 T/C cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs263063 0.834 rs11673509 chr19:5080647 A/G cg18473234 chr19:5097819 KDM4B -0.57 -7.17 -0.36 4.73e-12 Periodontitis (CDC/AAP); LIHC cis rs9420 0.961 rs7938083 chr11:57493622 C/A cg19752551 chr11:57585705 CTNND1 -0.48 -5.87 -0.3 1.02e-8 Schizophrenia; LIHC trans rs8002861 0.870 rs4942251 chr13:44440048 G/T cg17145862 chr1:211918768 LPGAT1 0.58 10.69 0.5 3.33e-23 Leprosy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24125890 chr12:21654287 RECQL;GOLT1B 0.47 6.91 0.35 2.42e-11 Pancreatic cancer; LIHC cis rs36051895 0.664 rs10815157 chr9:5108771 C/G cg02405213 chr9:5042618 JAK2 -0.64 -11.0 -0.51 2.67e-24 Pediatric autoimmune diseases; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs7264396 0.836 rs41293080 chr20:34187697 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -8.64 -0.42 2.21e-16 Total cholesterol levels; LIHC cis rs2637266 0.967 rs12246605 chr10:78352994 G/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs9467773 1.000 rs9393732 chr6:26530898 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC cis rs67981189 0.537 rs917067 chr14:71371904 C/T cg15816911 chr14:71606274 NA -0.41 -6.5 -0.33 2.83e-10 Schizophrenia; LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg02711726 chr17:80685570 FN3KRP -0.43 -7.84 -0.39 5.72e-14 Glycated hemoglobin levels; LIHC cis rs75920871 0.588 rs7112111 chr11:116980858 T/G cg01368799 chr11:117014884 PAFAH1B2 -0.47 -6.44 -0.33 4.01e-10 Subjective well-being; LIHC cis rs13191362 1.000 rs7764785 chr6:163009967 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg07167872 chr1:205819463 PM20D1 0.71 10.45 0.49 2.38e-22 Menarche (age at onset); LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg05185784 chr16:90016020 DEF8 -0.47 -6.13 -0.31 2.37e-9 Skin colour saturation; LIHC cis rs1823913 1.000 rs12623832 chr2:192125644 A/C cg12404831 chr2:192114017 MYO1B -0.33 -6.81 -0.35 4.5e-11 Obesity-related traits; LIHC cis rs8078723 1.000 rs59925331 chr17:38169273 C/G cg17467752 chr17:38218738 THRA 0.75 13.71 0.6 2.07e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs919433 0.783 rs788007 chr2:198233676 T/G cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.8e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs372883 0.638 rs117213 chr21:30720536 G/A cg24692254 chr21:30365293 RNF160 -0.49 -6.13 -0.31 2.37e-9 Pancreatic cancer; LIHC cis rs2224391 1.000 rs2753248 chr6:5262154 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg22907277 chr7:1156413 C7orf50 0.43 6.2 0.32 1.59e-9 Longevity;Endometriosis; LIHC cis rs3820068 0.581 rs72645877 chr1:15928106 G/T cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs9911578 0.967 rs3826353 chr17:57075299 C/T cg12560992 chr17:57184187 TRIM37 0.96 17.48 0.69 2.53e-49 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.926 rs11788825 chr9:111829757 T/G cg05043794 chr9:111880884 C9orf5 -0.27 -6.18 -0.32 1.78e-9 Menarche (age at onset); LIHC cis rs2070488 0.662 rs7372545 chr3:38507570 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.58 8.1 0.4 9.9e-15 Electrocardiographic conduction measures; LIHC cis rs4474465 1.000 rs873311 chr11:78145886 G/C cg02023728 chr11:77925099 USP35 0.37 6.35 0.32 7.04e-10 Alzheimer's disease (survival time); LIHC cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg18357526 chr6:26021779 HIST1H4A 0.6 8.53 0.42 4.77e-16 Blood metabolite levels; LIHC trans rs1005277 0.579 rs1780139 chr10:38503018 C/T cg04469686 chr1:162760199 HSD17B7 -0.39 -6.03 -0.31 4.17e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2933343 0.729 rs1680785 chr3:128644816 C/T cg24203234 chr3:128598194 ACAD9 0.46 6.47 0.33 3.43e-10 IgG glycosylation; LIHC cis rs1494950 0.661 rs10433859 chr4:15072329 C/G cg12377275 chr4:15005593 CPEB2 -0.81 -7.23 -0.36 3.21e-12 Political ideology; LIHC cis rs787274 1.000 rs1361720 chr9:115535579 G/A cg13803584 chr9:115635662 SNX30 -0.54 -6.04 -0.31 4.12e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03170881 chr6:136571050 FAM54A -0.52 -6.15 -0.32 2.15e-9 Systolic blood pressure; LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs6450176 1.000 rs3776707 chr5:53304873 T/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.69 -0.62 3.11e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg20607798 chr8:58055168 NA 0.71 8.66 0.42 1.96e-16 Developmental language disorder (linguistic errors); LIHC cis rs7129220 0.512 rs57618276 chr11:10129276 C/T cg01453529 chr11:10209919 SBF2 -0.39 -6.8 -0.35 4.7e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs9303401 1.000 rs9904677 chr17:56873025 A/G cg05425664 chr17:57184151 TRIM37 -0.53 -7.51 -0.38 5.17e-13 Cognitive test performance; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg24846343 chr22:24311635 DDTL 0.68 13.29 0.58 8.94e-33 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs526821 0.595 rs532278 chr11:55344983 A/G cg04317927 chr11:55418816 OR4S2 0.47 8.98 0.44 1.87e-17 Pediatric bone mineral density (spine); LIHC cis rs4803468 1.000 rs4803468 chr19:41922352 A/G cg09537434 chr19:41945824 ATP5SL -1.03 -21.78 -0.76 1.34e-66 Height; LIHC cis rs9534288 0.619 rs9526143 chr13:46675991 C/T cg15192986 chr13:46630673 CPB2 -0.44 -6.11 -0.31 2.64e-9 Blood protein levels; LIHC cis rs796364 0.906 rs1658810 chr2:200816382 C/T cg23649088 chr2:200775458 C2orf69 0.5 5.92 0.3 7.77e-9 Schizophrenia; LIHC cis rs1865760 1.000 rs7739966 chr6:25906040 T/C cg03517284 chr6:25882590 NA -0.38 -5.72 -0.3 2.27e-8 Height; LIHC trans rs2727020 0.595 rs10466496 chr11:49501514 C/T cg03929089 chr4:120376271 NA -0.89 -17.99 -0.7 2.08e-51 Coronary artery disease; LIHC cis rs7945705 0.902 rs10769980 chr11:9014180 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.4 6.53 0.33 2.34e-10 Hemoglobin concentration; LIHC cis rs9811920 0.638 rs793440 chr3:99643176 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.49 -6.91 -0.35 2.37e-11 Axial length; LIHC cis rs2933343 0.818 rs6764681 chr3:128568380 G/C cg25356066 chr3:128598488 ACAD9 -0.52 -6.78 -0.34 5.27e-11 IgG glycosylation; LIHC cis rs7246657 0.943 rs7258692 chr19:37818829 C/A cg23950597 chr19:37808831 NA -0.55 -7.12 -0.36 6.56e-12 Coronary artery calcification; LIHC cis rs8141529 0.764 rs8137969 chr22:29228484 G/C cg15103426 chr22:29168792 CCDC117 0.67 11.37 0.52 1.29e-25 Lymphocyte counts; LIHC cis rs7945705 0.869 rs11042154 chr11:9029700 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.38 -6.19 -0.32 1.71e-9 Hemoglobin concentration; LIHC cis rs9902453 0.904 rs12952179 chr17:28412687 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.69 -11.01 -0.51 2.56e-24 Coffee consumption (cups per day); LIHC cis rs798554 0.704 rs798513 chr7:2782493 C/T cg19717773 chr7:2847554 GNA12 -0.4 -7.07 -0.36 8.52e-12 Height; LIHC cis rs943466 1.000 rs2395400 chr6:33770076 G/A cg25922239 chr6:33757077 LEMD2 -0.5 -6.29 -0.32 9.86e-10 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg07061783 chr6:25882402 NA -0.43 -6.03 -0.31 4.14e-9 Blood metabolite levels; LIHC cis rs1670533 1.000 rs6822863 chr4:1055606 G/A cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.38e-17 Recombination rate (females); LIHC cis rs9388451 0.874 rs1159974 chr6:126090277 C/T cg05901451 chr6:126070800 HEY2 0.75 17.42 0.69 4.11e-49 Brugada syndrome; LIHC cis rs61990749 0.597 rs59848135 chr14:78129000 G/C cg21497246 chr14:78225524 SNW1;C14orf178 0.45 6.76 0.34 5.84e-11 Fibroblast growth factor basic levels; LIHC cis rs12824058 0.831 rs4759657 chr12:130815818 G/A cg24838063 chr12:130822603 PIWIL1 0.66 9.79 0.47 4.16e-20 Menopause (age at onset); LIHC cis rs9790314 0.631 rs9867582 chr3:160797405 A/G cg03342759 chr3:160939853 NMD3 -0.67 -9.1 -0.44 7.46e-18 Morning vs. evening chronotype; LIHC cis rs4925386 1.000 rs2151512 chr20:60913495 T/C cg03945807 chr20:60948434 NA -0.35 -6.26 -0.32 1.17e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7447593 0.626 rs3812036 chr5:176813404 C/T cg16006841 chr5:176797999 RGS14 0.71 10.65 0.5 4.53e-23 Urinary electrolytes (magnesium/calcium ratio); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24980700 chr20:30410739 MYLK2 0.44 6.14 0.32 2.27e-9 Lung function (FEV1/FVC); LIHC cis rs3736485 0.903 rs750162 chr15:51907153 A/C cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.57e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9790314 1.000 rs9790314 chr3:161019558 T/C cg03342759 chr3:160939853 NMD3 -0.76 -10.83 -0.51 1.03e-23 Morning vs. evening chronotype; LIHC cis rs8180040 0.902 rs73081205 chr3:47517670 A/C cg27129171 chr3:47204927 SETD2 -0.57 -9.77 -0.47 4.76e-20 Colorectal cancer; LIHC cis rs67478160 0.643 rs4906369 chr14:104242458 T/C cg08213375 chr14:104286397 PPP1R13B 0.66 12.83 0.57 4.78e-31 Schizophrenia; LIHC cis rs8192917 0.895 rs2236338 chr14:25100282 A/G cg03875678 chr14:25103546 GZMB 0.4 7.33 0.37 1.63e-12 Vitiligo; LIHC cis rs1691799 0.899 rs1168300 chr12:66736467 C/A cg16791601 chr12:66731901 HELB -0.57 -13.85 -0.6 6.11e-35 White blood cell count (basophil); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01218756 chr4:48695242 FRYL 0.3 6.06 0.31 3.56e-9 Pancreatic cancer; LIHC cis rs4906332 1.000 rs34479426 chr14:103881823 G/C cg04998671 chr14:104000505 TRMT61A -0.45 -6.28 -0.32 1.04e-9 Coronary artery disease; LIHC cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg06481639 chr22:41940642 POLR3H -0.65 -6.64 -0.34 1.23e-10 Vitiligo; LIHC cis rs7833986 0.501 rs72653967 chr8:56999432 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.06e-16 Height; LIHC cis rs600806 0.850 rs10858092 chr1:109943893 A/G cg23091122 chr1:110024289 SYPL2 0.48 6.5 0.33 2.8e-10 Intelligence (multi-trait analysis); LIHC cis rs7937682 0.924 rs7924683 chr11:111555796 C/A cg09085632 chr11:111637200 PPP2R1B -1.07 -14.24 -0.61 1.88e-36 Primary sclerosing cholangitis; LIHC cis rs9590974 0.705 rs9526209 chr13:47219780 A/G cg04092803 chr13:47240378 LRCH1 0.28 6.01 0.31 4.76e-9 PR segment; LIHC cis rs875971 0.545 rs801199 chr7:66025273 A/G cg11764359 chr7:65958608 NA -0.62 -8.95 -0.44 2.34e-17 Aortic root size; LIHC cis rs9733 0.596 rs6685702 chr1:150656307 A/G cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Tonsillectomy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01028844 chr5:122736986 CEP120 -0.41 -6.64 -0.34 1.23e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs36051895 0.632 rs10121316 chr9:5147539 C/T cg02405213 chr9:5042618 JAK2 0.67 12.06 0.55 3.93e-28 Pediatric autoimmune diseases; LIHC cis rs1552244 0.554 rs3774207 chr3:9985656 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.57 8.06 0.4 1.29e-14 Alzheimer's disease; LIHC cis rs7582180 0.591 rs2241810 chr2:101011877 T/C cg14675211 chr2:100938903 LONRF2 0.54 8.24 0.41 3.59e-15 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg26338869 chr17:61819248 STRADA 0.59 8.69 0.43 1.5e-16 Prudent dietary pattern; LIHC cis rs6963495 0.818 rs73190202 chr7:105166510 A/G cg19920283 chr7:105172520 RINT1 0.7 6.58 0.34 1.76e-10 Bipolar disorder (body mass index interaction); LIHC cis rs7954584 0.520 rs1169096 chr12:122465836 G/C cg21171335 chr12:122356390 WDR66 -0.41 -6.73 -0.34 7.08e-11 Mean corpuscular volume; LIHC cis rs7116495 0.609 rs949326 chr11:71730306 A/G cg10381502 chr11:71823885 C11orf51 1.04 9.61 0.46 1.62e-19 Severe influenza A (H1N1) infection; LIHC trans rs10506458 1.000 rs12425932 chr12:63410497 C/A cg22491629 chr6:157744540 C6orf35 -0.59 -10.83 -0.51 1.05e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs8180040 0.966 rs34634681 chr3:47579102 G/A cg27129171 chr3:47204927 SETD2 -0.54 -8.61 -0.42 2.68e-16 Colorectal cancer; LIHC trans rs7618501 0.602 rs2240326 chr3:50128386 G/A cg21659725 chr3:3221576 CRBN -0.72 -11.53 -0.53 3.33e-26 Intelligence (multi-trait analysis); LIHC cis rs17095355 1.000 rs61614979 chr10:111743994 A/G cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.85 -0.3 1.15e-8 Biliary atresia; LIHC cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg03806693 chr22:41940476 POLR3H -0.96 -10.28 -0.49 8.78e-22 Vitiligo; LIHC cis rs1577917 1.000 rs12200330 chr6:86656653 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.22 -0.36 3.3e-12 Response to antipsychotic treatment; LIHC cis rs9427116 0.702 rs9427109 chr1:154609009 A/G cg17218026 chr1:154582156 ADAR 0.34 6.51 0.33 2.65e-10 Blood protein levels; LIHC trans rs1005277 0.540 rs2145487 chr10:38010077 A/G cg27523141 chr10:43048294 ZNF37B 0.4 7.01 0.35 1.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg05590025 chr7:65112418 INTS4L2 -0.62 -6.85 -0.35 3.39e-11 Diabetic kidney disease; LIHC cis rs908922 0.676 rs493133 chr1:152493875 G/C cg20991723 chr1:152506922 NA 0.59 10.39 0.49 3.62e-22 Hair morphology; LIHC cis rs796364 0.806 rs10445791 chr2:201078307 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -7.99 -0.4 2.16e-14 Schizophrenia; LIHC cis rs155076 0.938 rs9509630 chr13:21844314 G/A cg11317459 chr13:21872234 NA -1.17 -13.06 -0.58 6.87e-32 White matter hyperintensity burden; LIHC cis rs10751667 0.666 rs7936830 chr11:959686 A/G cg10932868 chr11:921992 NA 0.39 7.27 0.37 2.53e-12 Alzheimer's disease (late onset); LIHC trans rs2727020 0.894 rs2866361 chr11:49372481 A/G cg15704280 chr7:45808275 SEPT13 -0.74 -11.25 -0.52 3.48e-25 Coronary artery disease; LIHC cis rs703842 1.000 rs11172351 chr12:58213485 C/T cg18357645 chr12:58087776 OS9 -0.41 -6.28 -0.32 1.05e-9 Multiple sclerosis; LIHC cis rs6060717 0.553 rs2590958 chr20:34616590 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -7.91 -0.39 3.49e-14 Hip circumference adjusted for BMI; LIHC cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10242455 0.702 rs73397499 chr7:99039627 T/C cg18809830 chr7:99032528 PTCD1 -0.83 -6.45 -0.33 3.76e-10 Blood metabolite levels; LIHC cis rs6964587 0.967 rs12538325 chr7:91757479 A/G cg17063962 chr7:91808500 NA 1.02 19.48 0.73 2.12e-57 Breast cancer; LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg07332563 chr6:291687 DUSP22 -0.52 -7.19 -0.36 4e-12 Menopause (age at onset); LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg04234412 chr22:24373322 LOC391322 0.66 9.55 0.46 2.6e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg08219700 chr8:58056026 NA 0.52 6.93 0.35 2.08e-11 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs35871601 chr21:46675214 C/T cg11663144 chr21:46675770 NA -0.32 -5.92 -0.31 7.69e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs61931739 0.500 rs7309421 chr12:34553795 C/T cg26384229 chr12:38710491 ALG10B 0.77 9.43 0.45 6.43e-19 Morning vs. evening chronotype; LIHC cis rs265548 0.646 rs36692 chr19:17906839 C/T cg04517722 chr19:17905589 B3GNT3 0.45 6.97 0.35 1.59e-11 Tumor biomarkers; LIHC cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg03264133 chr6:25882463 NA 0.6 8.4 0.41 1.2e-15 Blood metabolite levels; LIHC trans rs877282 0.898 rs11253346 chr10:765313 A/G cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs703842 1.000 rs2069502 chr12:58144665 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.84 -12.65 -0.56 2.4e-30 Multiple sclerosis; LIHC cis rs2268241 0.938 rs2268242 chr21:34781104 C/T cg14850771 chr21:34775459 IFNGR2 0.91 13.78 0.6 1.18e-34 Obesity-related traits; LIHC cis rs2404602 0.692 rs3110382 chr15:77148688 G/A cg23625390 chr15:77176239 SCAPER -0.35 -5.86 -0.3 1.08e-8 Blood metabolite levels; LIHC cis rs6088580 0.524 rs6088564 chr20:33249444 A/G cg07148914 chr20:33460835 GGT7 -0.51 -7.19 -0.36 4.11e-12 Glomerular filtration rate (creatinine); LIHC cis rs7264396 1.000 rs224418 chr20:34142527 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.38 -6.67 -0.34 1e-10 Total cholesterol levels; LIHC cis rs4891159 0.548 rs11150952 chr18:74128188 T/C cg24786174 chr18:74118243 ZNF516 0.84 17.43 0.69 3.78e-49 Longevity; LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg09033563 chr22:24373618 LOC391322 0.45 5.98 0.31 5.77e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9911578 1.000 rs6503887 chr17:56993320 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.602 rs1780141 chr10:38504299 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3096299 0.933 rs2965824 chr16:89455306 A/G cg02187348 chr16:89574699 SPG7 0.46 6.83 0.35 3.94e-11 Multiple myeloma (IgH translocation); LIHC cis rs7727544 0.645 rs272857 chr5:131685297 G/A cg07395648 chr5:131743802 NA -0.3 -6.22 -0.32 1.42e-9 Blood metabolite levels; LIHC cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg05590025 chr7:65112418 INTS4L2 0.58 6.43 0.33 4.21e-10 Diabetic kidney disease; LIHC cis rs1385374 0.698 rs2170988 chr12:129290876 A/C cg09035930 chr12:129282057 SLC15A4 -0.5 -5.96 -0.31 6.13e-9 Systemic lupus erythematosus; LIHC cis rs9318086 0.534 rs17338049 chr13:24382148 G/C cg25267304 chr13:24462978 PCOTH;MIPEP -0.35 -5.89 -0.3 9.42e-9 Myopia (pathological); LIHC cis rs1577917 0.771 rs4383777 chr6:86435960 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.39 7.15 0.36 5.17e-12 Response to antipsychotic treatment; LIHC cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.76 5.84 0.3 1.24e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4843747 0.636 rs11864872 chr16:88105966 A/G cg00677901 chr16:88017247 BANP 0.51 7.85 0.39 5.52e-14 Menopause (age at onset); LIHC cis rs6088580 0.524 rs6088552 chr20:33226491 A/G cg07148914 chr20:33460835 GGT7 -0.5 -7.14 -0.36 5.77e-12 Glomerular filtration rate (creatinine); LIHC trans rs561341 0.843 rs4795666 chr17:30241409 A/G cg20587970 chr11:113659929 NA -0.58 -7.1 -0.36 7.31e-12 Hip circumference adjusted for BMI; LIHC cis rs738322 0.967 rs4380 chr22:38569529 T/C cg25457927 chr22:38595422 NA -0.25 -6.27 -0.32 1.07e-9 Cutaneous nevi; LIHC cis rs986417 0.901 rs1007152 chr14:60999493 C/T cg27398547 chr14:60952738 C14orf39 0.74 8.26 0.41 3.28e-15 Gut microbiota (bacterial taxa); LIHC cis rs6942756 0.531 rs7800983 chr7:128971130 C/T cg02491457 chr7:128862824 NA 0.5 7.87 0.39 4.64e-14 White matter hyperintensity burden; LIHC cis rs9640161 0.673 rs34489187 chr7:150044379 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.2 -0.41 4.94e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs4713118 0.513 rs149944 chr6:28002818 C/T cg23485639 chr6:28045615 ZNF165 0.39 5.94 0.31 7.13e-9 Parkinson's disease; LIHC cis rs9297145 0.565 rs941001 chr7:98735185 A/T cg05967295 chr7:98741636 SMURF1 -0.37 -6.2 -0.32 1.58e-9 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs13108904 0.875 rs1564509 chr4:1236562 C/G cg00684032 chr4:1343700 KIAA1530 0.38 6.45 0.33 3.75e-10 Obesity-related traits; LIHC cis rs2455601 0.638 rs3815991 chr11:9007669 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.47 6.62 0.34 1.42e-10 Schizophrenia; LIHC cis rs4794202 0.629 rs7214694 chr17:45895353 C/T cg10638573 chr17:45915098 SCRN2 0.56 5.95 0.31 6.47e-9 Alzheimer's disease (cognitive decline); LIHC cis rs7772486 0.727 rs10447449 chr6:146138707 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -6.1 -0.31 2.86e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 1.000 rs3088215 chr16:28853996 A/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs6952808 0.656 rs11764212 chr7:2067593 C/A cg04565464 chr8:145669602 NFKBIL2 0.4 6.72 0.34 7.64e-11 Bipolar disorder and schizophrenia; LIHC cis rs35146811 0.961 rs11771139 chr7:99736059 C/T cg13334819 chr7:99746414 C7orf59 -0.57 -8.07 -0.4 1.24e-14 Coronary artery disease; LIHC cis rs6089584 0.546 rs4925337 chr20:60637637 T/C cg06108461 chr20:60628389 TAF4 -0.57 -7.32 -0.37 1.75e-12 Body mass index; LIHC cis rs2153535 0.580 rs6912374 chr6:8456423 T/C cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs7635838 0.964 rs7624086 chr3:11412620 C/G cg00170343 chr3:11313890 ATG7 0.45 7.24 0.36 2.91e-12 HDL cholesterol; LIHC cis rs11122272 0.525 rs2749713 chr1:231537921 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.49 -0.49 1.66e-22 Hemoglobin concentration; LIHC cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg22800045 chr5:56110881 MAP3K1 0.59 7.06 0.36 9.36e-12 Type 2 diabetes; LIHC cis rs7296418 0.738 rs10846489 chr12:123743927 A/G cg05973401 chr12:123451056 ABCB9 -0.42 -6.23 -0.32 1.34e-9 Platelet count; LIHC cis rs881375 1.000 rs1609810 chr9:123642351 C/T cg14580859 chr9:123691850 NA 0.37 6.55 0.33 2.07e-10 Rheumatoid arthritis; LIHC cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg13047869 chr3:10149882 C3orf24 0.53 6.86 0.35 3.24e-11 Alzheimer's disease; LIHC cis rs6964587 1.000 rs2106171 chr7:91750450 A/G cg17063962 chr7:91808500 NA 1.02 19.7 0.73 2.9e-58 Breast cancer; LIHC cis rs3862260 0.509 rs10923879 chr1:120163831 A/G cg16322792 chr1:120165303 ZNF697 0.52 9.46 0.46 5.04e-19 Systemic lupus erythematosus; LIHC cis rs7264396 1.000 rs7264396 chr20:34154741 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.38 6.78 0.34 5.19e-11 Total cholesterol levels; LIHC cis rs7772486 0.790 rs2254283 chr6:146204289 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.92 -0.3 8.03e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2180341 0.695 rs6569487 chr6:127726196 C/T cg27446573 chr6:127587934 RNF146 -0.59 -9.4 -0.45 8.16e-19 Breast cancer; LIHC cis rs875971 0.545 rs73152714 chr7:65999628 G/A cg11764359 chr7:65958608 NA 0.61 8.83 0.43 5.48e-17 Aortic root size; LIHC cis rs7659604 1.000 rs34952897 chr4:122664409 C/T cg19748678 chr4:122722346 EXOSC9 0.36 6.0 0.31 5.03e-9 Type 2 diabetes; LIHC cis rs9811920 0.609 rs13317017 chr3:99665521 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.15 0.36 5.37e-12 Axial length; LIHC trans rs35110281 0.627 rs1436291 chr21:44965485 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.49 6.74 0.34 6.68e-11 Mean corpuscular volume; LIHC cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs34779708 0.931 rs11010132 chr10:35517265 C/G cg03585969 chr10:35415529 CREM 0.84 12.63 0.56 2.91e-30 Inflammatory bowel disease;Crohn's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17258537 chr5:179401804 RNF130 0.46 6.72 0.34 7.68e-11 Longevity; LIHC cis rs11955398 0.716 rs56191602 chr5:59954444 T/A cg02684056 chr5:59996105 DEPDC1B 0.4 5.91 0.3 8.27e-9 Intelligence (multi-trait analysis); LIHC cis rs9300255 0.568 rs1627724 chr12:123638580 T/A cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs950776 0.616 rs56276142 chr15:78889795 T/C cg06917634 chr15:78832804 PSMA4 0.64 8.91 0.43 3.17e-17 Sudden cardiac arrest; LIHC cis rs2439831 0.850 rs12702 chr15:44093927 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.44 -6.69 -0.34 9.4e-11 Lung cancer in ever smokers; LIHC cis rs713477 0.967 rs4901565 chr14:55912508 T/G cg13175173 chr14:55914753 NA -0.36 -8.26 -0.41 3.34e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs6502050 0.871 rs62079998 chr17:80077245 A/C cg11859384 chr17:80120422 CCDC57 0.42 5.74 0.3 2.07e-8 Life satisfaction; LIHC cis rs11048434 0.736 rs11048338 chr12:9121362 C/G cg04155231 chr12:9217510 LOC144571 0.31 5.85 0.3 1.12e-8 Sjögren's syndrome; LIHC cis rs17401966 1.000 rs1536263 chr1:10378914 T/C cg19773385 chr1:10388646 KIF1B -0.47 -8.15 -0.4 6.71e-15 Hepatocellular carcinoma; LIHC trans rs12478296 0.681 rs55802421 chr2:243033962 C/T cg01596870 chr19:55963115 NA -0.62 -8.17 -0.4 5.86e-15 Obesity-related traits; LIHC cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg19318889 chr4:1322082 MAEA 0.47 6.59 0.34 1.68e-10 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02181963 chr13:111358803 CARS2 0.48 6.05 0.31 3.73e-9 Lung function (FEV1/FVC); LIHC cis rs7572733 0.534 rs700673 chr2:198692929 A/G cg00792783 chr2:198669748 PLCL1 0.46 6.82 0.35 4.1e-11 Dermatomyositis; LIHC cis rs5769765 0.955 rs2295406 chr22:50260169 G/A cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs6456156 0.586 rs6456149 chr6:167463902 T/C cg12798992 chr6:167411361 FGFR1OP 0.41 6.47 0.33 3.49e-10 Primary biliary cholangitis; LIHC cis rs2404602 0.735 rs4886495 chr15:76738959 C/T cg23625390 chr15:77176239 SCAPER 0.49 8.16 0.4 6.5e-15 Blood metabolite levels; LIHC cis rs372883 0.563 rs1153293 chr21:30691325 C/T cg24692254 chr21:30365293 RNF160 0.58 7.64 0.38 2.2e-13 Pancreatic cancer; LIHC cis rs7923837 0.687 rs1111875 chr10:94462882 C/T cg25506282 chr10:94462361 NA 0.37 6.64 0.34 1.24e-10 Body mass index;Multiple sclerosis; LIHC cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg09417038 chr21:47716443 C21orf57 -0.52 -7.99 -0.4 2.03e-14 Testicular germ cell tumor; LIHC cis rs9473924 0.580 rs58105163 chr6:50832730 C/T cg14470998 chr6:50812995 TFAP2B 0.89 10.22 0.48 1.42e-21 Body mass index; LIHC cis rs2404602 0.692 rs55676827 chr15:76961716 C/T cg03037974 chr15:76606532 NA 0.74 14.52 0.62 1.54e-37 Blood metabolite levels; LIHC cis rs35306767 0.807 rs61831436 chr10:837882 G/A cg26597838 chr10:835615 NA 1.4 15.14 0.63 5.6e-40 Eosinophil percentage of granulocytes; LIHC cis rs10791097 0.694 rs4457753 chr11:130755575 A/G cg22079354 chr11:130786696 SNX19 0.42 5.95 0.31 6.74e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs9837602 0.938 rs1021341 chr3:99786289 A/G cg08687515 chr19:58661962 ZNF329 0.47 6.16 0.32 2e-9 Breast cancer; LIHC trans rs1493916 0.748 rs4799355 chr18:31313124 G/T cg27147174 chr7:100797783 AP1S1 -0.46 -6.69 -0.34 9.28e-11 Life satisfaction; LIHC cis rs116095464 0.558 rs9654452 chr5:299561 C/T cg22857025 chr5:266934 NA -1.48 -18.06 -0.7 1.11e-51 Breast cancer; LIHC cis rs950027 0.787 rs1547487 chr15:45723983 A/G cg26924012 chr15:45694286 SPATA5L1 0.63 10.09 0.48 4.09e-21 Response to fenofibrate (adiponectin levels); LIHC cis rs1336900 0.544 rs10888386 chr1:150611957 A/G cg13175981 chr1:150552382 MCL1 0.51 7.2 0.36 3.96e-12 Blood protein levels; LIHC cis rs12477438 0.748 rs10200974 chr2:99675227 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs6062302 0.522 rs2297427 chr20:62221364 G/A cg06363034 chr20:62225388 GMEB2 -0.45 -7.58 -0.38 3.23e-13 Glioblastoma; LIHC cis rs1975974 1.000 rs67946006 chr17:21723940 T/C cg18423549 chr17:21743878 NA -0.45 -5.94 -0.31 7.19e-9 Psoriasis; LIHC trans rs1814175 0.615 rs12417290 chr11:49876951 G/A cg15704280 chr7:45808275 SEPT13 -0.95 -19.96 -0.73 2.55e-59 Height; LIHC cis rs10791323 0.575 rs4489760 chr11:133732265 A/T cg06766960 chr11:133703094 NA -0.59 -9.38 -0.45 9.64e-19 Childhood ear infection; LIHC cis rs7937890 0.631 rs7118886 chr11:14427517 T/C cg22961513 chr11:14280813 SPON1 -0.44 -6.43 -0.33 4.28e-10 Mitochondrial DNA levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09637470 chr11:109963583 ZC3H12C 0.48 6.71 0.34 8.24e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.863 rs13136462 chr4:120543173 C/T cg25214090 chr10:38739885 LOC399744 0.56 8.99 0.44 1.72e-17 Corneal astigmatism; LIHC trans rs561341 0.739 rs9906455 chr17:30215669 G/A cg20587970 chr11:113659929 NA 0.53 6.95 0.35 1.85e-11 Hip circumference adjusted for BMI; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg05185784 chr16:90016020 DEF8 -0.46 -5.95 -0.31 6.75e-9 Skin colour saturation; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02878701 chr21:47706221 MCM3AP;C21orf57 0.43 6.15 0.32 2.18e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs769267 0.965 rs2905425 chr19:19475717 G/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.58 -8.98 -0.44 1.78e-17 Tonsillectomy; LIHC trans rs2073499 0.872 rs7642692 chr3:50222693 T/C cg21659725 chr3:3221576 CRBN 0.67 8.08 0.4 1.16e-14 Schizophrenia; LIHC trans rs1920116 0.778 rs4352416 chr3:169554084 G/A cg00669760 chr2:44735195 C2orf34 0.38 6.05 0.31 3.79e-9 Glioma (high-grade); LIHC cis rs7647973 0.626 rs4855849 chr3:49653378 A/G cg03060546 chr3:49711283 APEH 0.59 6.78 0.34 5.41e-11 Menarche (age at onset); LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg04267008 chr7:1944627 MAD1L1 -0.59 -9.0 -0.44 1.6e-17 Bipolar disorder and schizophrenia; LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.95 -0.4 2.68e-14 Lymphocyte counts; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg14417382 chr12:64616000 C12orf66 -0.4 -6.19 -0.32 1.71e-9 Immature fraction of reticulocytes; LIHC cis rs7552404 0.690 rs11161620 chr1:76255228 A/G cg03433033 chr1:76189801 ACADM -0.59 -7.7 -0.38 1.48e-13 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00594016 chr16:19721831 C16orf88 0.39 6.72 0.34 7.41e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25618672 chr7:65939712 NA 0.42 6.43 0.33 4.18e-10 Immature fraction of reticulocytes; LIHC cis rs965469 0.779 rs6037515 chr20:3233091 C/A cg25506879 chr20:3388711 C20orf194 -0.51 -6.24 -0.32 1.3e-9 IFN-related cytopenia; LIHC cis rs17106184 1.000 rs1015085 chr1:51260668 C/A cg07174182 chr1:51127561 FAF1 -0.64 -6.93 -0.35 2.1e-11 Type 2 diabetes; LIHC cis rs1448094 0.512 rs60986162 chr12:86247054 T/G cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC cis rs4319547 1.000 rs6489157 chr12:123101673 C/G cg23029597 chr12:123009494 RSRC2 0.49 6.95 0.35 1.88e-11 Body mass index; LIHC cis rs1008375 1.000 rs9291659 chr4:17662360 A/C cg02297831 chr4:17616191 MED28 0.42 6.56 0.33 1.98e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11190604 1.000 rs7099965 chr10:102301165 A/G cg07080220 chr10:102295463 HIF1AN 0.52 7.23 0.36 3.13e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3761847 0.622 rs1323471 chr9:123826315 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.42 5.85 0.3 1.17e-8 Rheumatoid arthritis; LIHC cis rs7520050 0.966 rs6675946 chr1:46371774 G/T cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.97e-9 Red blood cell count;Reticulocyte count; LIHC cis rs425277 0.500 rs908744 chr1:2038893 G/A cg04315214 chr1:2043799 PRKCZ 0.37 6.01 0.31 4.72e-9 Height; LIHC cis rs12701220 0.522 rs12701455 chr7:1055409 A/G cg16145915 chr7:1198662 ZFAND2A -0.28 -6.01 -0.31 4.74e-9 Bronchopulmonary dysplasia; LIHC trans rs6912958 0.712 rs6930600 chr6:88349787 G/A cg23605328 chr1:201951606 RNPEP 0.38 6.07 0.31 3.35e-9 Monocyte percentage of white cells; LIHC cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg00166722 chr3:10149974 C3orf24 0.51 5.84 0.3 1.19e-8 Alzheimer's disease; LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg00091569 chr3:40428383 ENTPD3 0.41 6.78 0.34 5.36e-11 Renal cell carcinoma; LIHC cis rs7772486 0.754 rs1415747 chr6:146077249 A/G cg13319975 chr6:146136371 FBXO30 -0.4 -6.65 -0.34 1.18e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1577917 0.958 rs12193904 chr6:86452703 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.45 -0.37 7.86e-13 Response to antipsychotic treatment; LIHC cis rs9640161 0.830 rs76741564 chr7:150059529 A/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.41 -0.41 1.12e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs7635838 0.586 rs379241 chr3:11291565 G/A cg00170343 chr3:11313890 ATG7 0.59 9.75 0.47 5.42e-20 HDL cholesterol; LIHC trans rs116095464 0.614 rs28736753 chr5:274081 G/A cg00938859 chr5:1591904 SDHAP3 0.54 6.59 0.34 1.63e-10 Breast cancer; LIHC cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg07092213 chr7:1199455 ZFAND2A -0.46 -6.85 -0.35 3.48e-11 Longevity;Endometriosis; LIHC cis rs17253792 0.822 rs113350960 chr14:56087713 G/A cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs907683 0.584 rs2070927 chr2:220282955 C/T cg15015639 chr2:220282977 DES 0.36 8.53 0.42 4.88e-16 Resting heart rate; LIHC cis rs634534 0.561 rs613924 chr11:65769295 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.25 0.45 2.51e-18 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs2153535 0.580 rs2327056 chr6:8443305 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs600806 0.850 rs10776807 chr1:109956156 A/G cg02415029 chr1:110025642 ATXN7L2 0.45 5.95 0.31 6.75e-9 Intelligence (multi-trait analysis); LIHC cis rs2180341 1.000 rs9375499 chr6:127618072 T/C cg24812749 chr6:127587940 RNF146 1.07 16.08 0.66 9.77e-44 Breast cancer; LIHC cis rs34779708 0.931 rs1926554 chr10:35344969 C/T cg03585969 chr10:35415529 CREM 0.86 12.99 0.57 1.26e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9291683 0.609 rs34709913 chr4:10028955 T/C cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.77e-13 Bone mineral density; LIHC cis rs66573146 0.572 rs67922134 chr4:6955772 G/A cg00086871 chr4:6988644 TBC1D14 0.8 6.06 0.31 3.61e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs77861329 1.000 rs57335685 chr3:52098458 C/T cg08692210 chr3:52188851 WDR51A 0.79 6.99 0.35 1.44e-11 Macrophage inflammatory protein 1b levels; LIHC cis rs10847980 0.590 rs12319654 chr12:123327160 C/T cg25930673 chr12:123319894 HIP1R 1.14 12.88 0.57 3.08e-31 Adiponectin levels; LIHC cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs240764 0.658 rs705585 chr6:101262409 A/G cg09795085 chr6:101329169 ASCC3 0.55 7.72 0.39 1.28e-13 Neuroticism; LIHC cis rs853679 0.517 rs11552219 chr6:28126834 C/T cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC trans rs7714584 1.000 rs11955172 chr5:150254378 T/C cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs78545713 1.000 rs77281308 chr6:26250029 C/T cg16070018 chr6:26224392 HIST1H3E 0.67 7.14 0.36 5.72e-12 Iron status biomarkers (total iron binding capacity); LIHC cis rs6964587 0.626 rs6951795 chr7:91543764 T/C cg17063962 chr7:91808500 NA -0.61 -10.93 -0.51 4.8e-24 Breast cancer; LIHC cis rs6598955 0.612 rs12738188 chr1:26548029 G/C cg04990556 chr1:26633338 UBXN11 -0.55 -9.05 -0.44 1.12e-17 Obesity-related traits; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.23 -0.32 1.39e-9 Total body bone mineral density; LIHC cis rs7107174 1.000 rs2511187 chr11:77985849 T/A cg02023728 chr11:77925099 USP35 0.49 9.39 0.45 8.68e-19 Testicular germ cell tumor; LIHC cis rs9303401 0.614 rs34683543 chr17:56520036 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.89 12.11 0.55 2.56e-28 Cognitive test performance; LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg10755058 chr3:40428713 ENTPD3 0.4 6.91 0.35 2.44e-11 Renal cell carcinoma; LIHC cis rs1983891 0.874 rs3747744 chr6:41516351 A/G cg20194872 chr6:41519635 FOXP4 0.41 6.5 0.33 2.78e-10 Prostate cancer; LIHC trans rs1814175 0.645 rs1722000 chr11:49917928 A/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs7264396 0.836 rs6058275 chr20:34186331 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -8.75 -0.43 9.96e-17 Total cholesterol levels; LIHC cis rs3806843 0.735 rs778595 chr5:140036681 G/A cg16179182 chr5:140090404 VTRNA1-1 0.36 5.95 0.31 6.72e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7106204 1.000 rs7106204 chr11:24236096 C/T ch.11.24196551F chr11:24239977 NA -0.6 -6.61 -0.34 1.47e-10 Response to Homoharringtonine (cytotoxicity); LIHC cis rs7246657 0.943 rs7259968 chr19:37811854 T/C cg23950597 chr19:37808831 NA -0.44 -6.04 -0.31 4.12e-9 Coronary artery calcification; LIHC cis rs11098499 0.866 rs12501602 chr4:120287935 A/T cg09307838 chr4:120376055 NA 0.64 9.64 0.46 1.32e-19 Corneal astigmatism; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg18538332 chr22:24372958 LOC391322 -0.65 -9.85 -0.47 2.62e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7659604 0.521 rs4833234 chr4:122694799 T/C cg19671926 chr4:122722719 EXOSC9 0.56 8.52 0.42 5.25e-16 Type 2 diabetes; LIHC cis rs2976388 0.578 rs3736010 chr8:143817503 T/C cg24634471 chr8:143751801 JRK -0.43 -5.99 -0.31 5.35e-9 Urinary tract infection frequency; LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs6835098 0.923 rs7671278 chr4:174095769 A/G cg27433088 chr4:174089019 GALNT7 0.41 7.0 0.35 1.39e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs2239547 0.657 rs4687554 chr3:52864135 T/C cg11645453 chr3:52864694 ITIH4 0.34 8.85 0.43 4.91e-17 Schizophrenia; LIHC cis rs36051895 0.659 rs12339666 chr9:5063296 A/C cg02405213 chr9:5042618 JAK2 0.7 13.13 0.58 3.49e-32 Pediatric autoimmune diseases; LIHC trans rs3758911 0.796 rs56753250 chr11:107209225 T/A cg21068293 chr15:74496576 STRA6 0.26 6.19 0.32 1.74e-9 Coronary artery disease; LIHC cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg00149659 chr3:10157352 C3orf10 0.7 7.14 0.36 5.55e-12 Alzheimer's disease; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg08331733 chr4:113332969 ALPK1 0.46 6.8 0.35 4.6e-11 Bilirubin levels; LIHC trans rs7618501 1.000 rs9872864 chr3:49792023 A/G cg21659725 chr3:3221576 CRBN -0.99 -19.64 -0.73 4.88e-58 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs1414345 chr6:8471537 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs9768139 0.733 rs12698208 chr7:158117575 C/T cg25566285 chr7:158114605 PTPRN2 0.23 6.19 0.32 1.68e-9 Calcium levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21942256 chr3:156892528 NA 0.46 6.09 0.31 2.99e-9 Lung function (FEV1/FVC); LIHC cis rs28655083 0.828 rs11640648 chr16:77122494 T/C cg09454613 chr16:77233327 SYCE1L;MON1B -0.4 -6.06 -0.31 3.58e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1670533 0.818 rs643484 chr4:1085826 A/G cg27284194 chr4:1044797 NA 0.61 8.97 0.44 1.94e-17 Recombination rate (females); LIHC cis rs2599510 0.703 rs762023 chr2:32713170 G/A cg02381751 chr2:32503542 YIPF4 0.48 6.2 0.32 1.64e-9 Interleukin-18 levels; LIHC cis rs765787 0.530 rs4444275 chr15:45535347 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs8141529 0.843 rs1065497 chr22:29279991 C/T cg02153584 chr22:29168773 CCDC117 0.53 8.09 0.4 1.02e-14 Lymphocyte counts; LIHC cis rs904251 0.772 rs2252920 chr6:37418327 A/G cg01843034 chr6:37503916 NA -0.39 -6.22 -0.32 1.48e-9 Cognitive performance; LIHC trans rs1814175 0.935 rs11040462 chr11:49683158 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -21.89 -0.76 4.92e-67 Height; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg07332563 chr6:291687 DUSP22 -0.52 -7.24 -0.36 3.05e-12 Menopause (age at onset); LIHC cis rs10744422 1.000 rs936083 chr12:123338964 A/G cg25930673 chr12:123319894 HIP1R -0.96 -12.76 -0.57 9.14e-31 Schizophrenia; LIHC cis rs7100689 0.753 rs2185426 chr10:82120887 G/A cg01528321 chr10:82214614 TSPAN14 0.87 11.84 0.54 2.43e-27 Post bronchodilator FEV1; LIHC cis rs6951245 0.529 rs76001997 chr7:1152615 C/T cg22907277 chr7:1156413 C7orf50 0.82 7.72 0.39 1.31e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2153535 0.580 rs4587214 chr6:8454119 T/C cg21535247 chr6:8435926 SLC35B3 0.64 8.54 0.42 4.51e-16 Motion sickness; LIHC cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg25072359 chr17:41440525 NA 0.37 5.81 0.3 1.4e-8 Menopause (age at onset); LIHC cis rs875971 0.545 rs10261710 chr7:65714189 T/A cg11764359 chr7:65958608 NA 0.5 6.8 0.35 4.71e-11 Aortic root size; LIHC cis rs875971 0.862 rs7803416 chr7:65954199 A/G cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg22903471 chr2:27725779 GCKR -0.51 -8.91 -0.43 2.99e-17 Total body bone mineral density; LIHC cis rs1577917 0.876 rs1582126 chr6:86697205 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.53 -0.33 2.32e-10 Response to antipsychotic treatment; LIHC cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg18357526 chr6:26021779 HIST1H4A 0.6 8.47 0.42 7.14e-16 Blood metabolite levels; LIHC cis rs10752881 1.000 rs10797802 chr1:182973158 A/T ch.1.3577855R chr1:183094577 LAMC1 -0.57 -10.0 -0.48 7.99e-21 Colorectal cancer; LIHC cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.33e-30 Menopause (age at onset); LIHC cis rs11971779 0.584 rs10236055 chr7:139069991 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs9309711 0.772 rs9752251 chr2:3489869 C/T cg10845886 chr2:3471009 TTC15 -0.57 -10.63 -0.5 5.57e-23 Neurofibrillary tangles; LIHC cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg18306943 chr3:40428807 ENTPD3 -0.34 -6.12 -0.31 2.62e-9 Renal cell carcinoma; LIHC cis rs1552244 0.572 rs59132826 chr3:10169725 G/A cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs6426558 0.572 rs2670471 chr1:227454328 T/C cg10327440 chr1:227177885 CDC42BPA 0.4 6.15 0.32 2.2e-9 Neutrophil percentage of white cells; LIHC cis rs9303401 0.659 rs34170300 chr17:56789905 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs2976388 0.578 rs13254358 chr8:143823876 G/A cg06565975 chr8:143823917 SLURP1 -0.46 -8.43 -0.41 1.01e-15 Urinary tract infection frequency; LIHC cis rs2303759 0.670 rs45549132 chr19:49794028 G/T cg22590775 chr19:49891494 CCDC155 0.5 7.93 0.39 3.1e-14 Multiple sclerosis; LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg03874509 chr1:107600012 PRMT6 0.76 12.17 0.55 1.44e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4713118 0.662 rs9468276 chr6:28027688 A/C cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs244293 0.965 rs244333 chr17:53204178 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.46 -6.75 -0.34 6.25e-11 Menarche (age at onset); LIHC cis rs3736594 1.000 rs12477908 chr2:27987046 A/C cg27432699 chr2:27873401 GPN1 -0.4 -6.25 -0.32 1.2e-9 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs769267 0.930 rs2304098 chr19:19646272 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.45 6.14 0.32 2.31e-9 Tonsillectomy; LIHC cis rs13161895 1.000 rs35135297 chr5:179469532 T/C cg02702477 chr5:179499311 RNF130 0.8 11.17 0.52 6.67e-25 LDL cholesterol; LIHC cis rs8180040 0.726 rs7628747 chr3:47001990 A/T cg27129171 chr3:47204927 SETD2 0.63 10.83 0.51 1.03e-23 Colorectal cancer; LIHC cis rs7089973 0.604 rs11196929 chr10:116582080 G/C cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs6674176 0.628 rs2301993 chr1:44426025 G/A cg12908607 chr1:44402522 ARTN -0.49 -8.3 -0.41 2.43e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3768617 0.510 rs4651140 chr1:183096952 G/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs425277 1.000 rs809912 chr1:2078385 C/T cg24578937 chr1:2090814 PRKCZ 0.5 8.92 0.43 2.77e-17 Height; LIHC cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg05665937 chr4:1216051 CTBP1 0.46 6.07 0.31 3.48e-9 Obesity-related traits; LIHC cis rs151997 0.569 rs10035173 chr5:50276059 C/G cg06027927 chr5:50259733 NA 0.54 6.6 0.34 1.61e-10 Callous-unemotional behaviour; LIHC cis rs1568889 1.000 rs34337978 chr11:28136746 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.91 0.35 2.36e-11 Bipolar disorder; LIHC cis rs2273156 0.706 rs7155696 chr14:35496754 G/A cg16230307 chr14:35515116 FAM177A1 -0.43 -6.19 -0.32 1.72e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs933688 1.000 rs6867219 chr5:90718008 T/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.37 0.66 6.68e-45 Smoking behavior; LIHC cis rs916888 0.773 rs199451 chr17:44801784 G/A cg01570182 chr17:44337453 NA 1.02 10.2 0.48 1.68e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4900538 0.927 rs1190547 chr14:102905087 G/C cg18135206 chr14:102964638 TECPR2 -0.94 -16.48 -0.67 2.41e-45 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6442522 0.533 rs2100544 chr3:15521665 G/A cg16303742 chr3:15540471 COLQ 0.36 5.76 0.3 1.87e-8 Uric acid levels; LIHC cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg14393609 chr7:65229607 NA 0.44 6.55 0.33 2.09e-10 Calcium levels; LIHC cis rs17685 0.753 rs10251863 chr7:75790192 T/C cg16684958 chr7:75615977 POR 0.52 8.53 0.42 4.68e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6963495 0.818 rs55825845 chr7:105166713 A/G cg19920283 chr7:105172520 RINT1 0.7 6.58 0.34 1.76e-10 Bipolar disorder (body mass index interaction); LIHC cis rs4901869 0.966 rs12148052 chr14:59338970 C/T cg02291164 chr14:59296302 NA 0.47 6.07 0.31 3.48e-9 Panic disorder; LIHC cis rs6920965 0.545 rs614031 chr6:126165720 A/C cg05901451 chr6:126070800 HEY2 -0.36 -6.29 -0.32 9.9e-10 High light scatter reticulocyte count; LIHC cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs748404 0.690 rs2244981 chr15:43752751 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.88 0.39 4.54e-14 Lung cancer; LIHC cis rs6582630 0.555 rs11610015 chr12:38508856 A/G cg26384229 chr12:38710491 ALG10B 0.66 9.54 0.46 2.87e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs7589728 0.514 rs78204719 chr2:88460747 G/C cg07952391 chr2:88470173 THNSL2 0.83 8.06 0.4 1.29e-14 Plasma clusterin levels; LIHC cis rs1707322 0.686 rs11211179 chr1:46228082 A/C cg03146154 chr1:46216737 IPP 0.55 9.47 0.46 4.84e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7188697 0.775 rs8056620 chr16:58604387 T/A cg02549819 chr16:58548995 SETD6 0.48 7.56 0.38 3.8e-13 QT interval; LIHC cis rs9457247 0.905 rs453184 chr6:167387404 A/C cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs769267 0.930 rs4808957 chr19:19567248 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.87 0.3 1.01e-8 Tonsillectomy; LIHC cis rs9858542 0.903 rs9875617 chr3:49634696 G/A cg03060546 chr3:49711283 APEH -0.52 -7.04 -0.36 1.04e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs10463316 0.894 rs6579865 chr5:150762335 A/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.02e-10 Metabolite levels (Pyroglutamine); LIHC trans rs6951245 0.554 rs11761322 chr7:1151657 A/G cg13565492 chr6:43139072 SRF -0.79 -7.4 -0.37 1.03e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg01995718 chr19:53913889 ZNF765 0.41 6.22 0.32 1.44e-9 Thyroid stimulating hormone; LIHC cis rs875971 0.895 rs12531677 chr7:65769086 G/A cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs870825 0.616 rs6419939 chr4:185642869 C/T cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs7208859 0.623 rs11651857 chr17:28926362 G/T cg13385521 chr17:29058706 SUZ12P 0.69 6.61 0.34 1.48e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 1.000 rs11974219 chr7:65647410 C/T cg11764359 chr7:65958608 NA -0.88 -15.37 -0.64 6.43e-41 Aortic root size; LIHC cis rs1008375 0.932 rs11941874 chr4:17666416 C/T cg16339924 chr4:17578868 LAP3 -0.46 -6.15 -0.32 2.19e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9682041 0.932 rs1525362 chr3:170070702 C/T cg11886554 chr3:170076028 SKIL 0.79 6.54 0.33 2.25e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs17270561 0.609 rs1165211 chr6:25800922 T/C cg17691542 chr6:26056736 HIST1H1C 0.43 5.97 0.31 5.84e-9 Iron status biomarkers; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.59 0.56 4.01e-30 Prudent dietary pattern; LIHC cis rs11628318 0.591 rs8010679 chr14:103155637 T/G cg12046867 chr14:103022105 NA 0.44 6.78 0.34 5.21e-11 Platelet count; LIHC cis rs10911232 0.507 rs35782443 chr1:183051502 A/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Hypertriglyceridemia; LIHC cis rs1863824 0.625 rs7091192 chr10:88167456 A/G cg07322936 chr10:88137208 NA -0.47 -6.04 -0.31 3.96e-9 Schizophrenia; LIHC cis rs600806 0.888 rs4970749 chr1:109873573 G/A cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.87 -0.3 1.04e-8 Intelligence (multi-trait analysis); LIHC cis rs7789940 1.000 rs17149161 chr7:75978229 C/A cg10167463 chr7:75959203 YWHAG -0.45 -7.06 -0.36 9.56e-12 Multiple sclerosis; LIHC cis rs11958404 0.932 rs72816563 chr5:157427447 C/T cg05962755 chr5:157440814 NA 0.97 10.89 0.51 6.51e-24 IgG glycosylation; LIHC cis rs4805272 0.626 rs12610050 chr19:29331324 A/T cg04546413 chr19:29218101 NA 0.4 6.79 0.34 5e-11 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs11711311 1.000 rs12637067 chr3:113527606 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.84 -0.35 3.76e-11 IgG glycosylation; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.25 -0.32 1.25e-9 Menopause (age at onset); LIHC cis rs709400 0.628 rs11622356 chr14:103912195 C/T cg26031613 chr14:104095156 KLC1 0.77 9.97 0.47 9.88e-21 Body mass index; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg14694896 chr8:104427370 SLC25A32;DCAF13 -0.45 -6.12 -0.31 2.53e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs17401966 1.000 rs11121532 chr1:10277898 G/T cg15208524 chr1:10270712 KIF1B 0.44 6.39 0.33 5.34e-10 Hepatocellular carcinoma; LIHC cis rs2421770 0.530 rs10836375 chr11:35353842 C/T cg13971030 chr11:35366721 SLC1A2 -0.4 -6.79 -0.34 4.83e-11 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs208515 0.525 rs10944863 chr6:66676238 C/T cg07460842 chr6:66804631 NA 0.76 8.85 0.43 4.72e-17 Exhaled nitric oxide levels; LIHC cis rs1062177 0.826 rs2915822 chr5:151130901 G/T cg00977110 chr5:151150581 G3BP1 -0.54 -6.86 -0.35 3.22e-11 Preschool internalizing problems; LIHC cis rs2066819 1.000 rs17118403 chr12:56630067 C/T cg26714650 chr12:56694279 CS -1.34 -12.2 -0.55 1.1e-28 Psoriasis vulgaris; LIHC cis rs1023500 0.596 rs133369 chr22:42463814 C/T cg00645731 chr22:42541494 CYP2D7P1 0.4 6.3 0.32 9.31e-10 Schizophrenia; LIHC cis rs72772090 0.710 rs11750399 chr5:96077940 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.64 -7.26 -0.37 2.71e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.72 0.3 2.33e-8 Electroencephalogram traits; LIHC cis rs1348850 0.872 rs4893959 chr2:178400204 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.82 12.56 0.56 5.04e-30 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs763121 0.853 rs1569492 chr22:38975511 A/G cg06544989 chr22:39130855 UNC84B -0.35 -5.86 -0.3 1.07e-8 Menopause (age at onset); LIHC cis rs9297145 0.724 rs6958790 chr7:98774738 C/T cg05967295 chr7:98741636 SMURF1 -0.72 -10.68 -0.5 3.55e-23 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg12792011 chr19:58661915 ZNF329 0.95 7.77 0.39 9.44e-14 Cholesterol, total; LIHC cis rs7296418 0.961 rs10773921 chr12:123541606 C/T cg06742321 chr12:123595122 PITPNM2 0.31 5.83 0.3 1.31e-8 Platelet count; LIHC cis rs3768617 0.510 rs10911247 chr1:183076993 A/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.66 0.5 4.19e-23 Fuchs's corneal dystrophy; LIHC cis rs2204008 0.747 rs11514040 chr12:38201040 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.67 0.5 3.86e-23 Bladder cancer; LIHC cis rs9309711 0.772 rs9309714 chr2:3491830 G/C cg10845886 chr2:3471009 TTC15 -0.61 -11.04 -0.51 1.86e-24 Neurofibrillary tangles; LIHC cis rs72781680 0.898 rs12612492 chr2:24093756 C/T cg08917208 chr2:24149416 ATAD2B 0.91 8.45 0.42 8.67e-16 Lymphocyte counts; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg04125373 chr11:65430610 RELA 0.48 6.12 0.31 2.6e-9 Hepatitis; LIHC cis rs61008539 0.741 rs11767322 chr7:867405 A/G cg15782153 chr7:917662 C7orf20 0.41 5.94 0.31 6.95e-9 Perceived unattractiveness to mosquitoes; LIHC cis rs56775891 1.000 rs4799088 chr18:77573548 A/G cg13263691 chr18:77568018 NA 0.24 6.73 0.34 7.32e-11 Schizophrenia; LIHC cis rs1419980 0.722 rs752452 chr12:7781021 G/A cg25828445 chr12:7781288 NA 0.44 6.82 0.35 4.27e-11 HDL cholesterol levels; LIHC cis rs703842 0.642 rs73123375 chr12:58063664 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.56 7.61 0.38 2.67e-13 Multiple sclerosis; LIHC cis rs864643 1.000 rs1340224 chr3:39549563 C/A cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs7520050 0.581 rs6671303 chr1:46629653 A/C cg15696662 chr1:46669221 C1orf190;POMGNT1 -0.43 -6.65 -0.34 1.17e-10 Red blood cell count;Reticulocyte count; LIHC cis rs1559088 0.948 rs12460195 chr19:33584479 G/A cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs35306767 0.855 rs12761180 chr10:872086 C/T cg26597838 chr10:835615 NA 1.5 16.55 0.67 1.29e-45 Eosinophil percentage of granulocytes; LIHC cis rs1005277 0.579 rs2505196 chr10:38393563 G/A cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg21724239 chr8:58056113 NA 0.47 6.34 0.32 7.19e-10 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.790 rs9403755 chr6:146231470 C/A cg23711669 chr6:146136114 FBXO30 -0.64 -11.19 -0.52 5.72e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs3736485 0.966 rs7161973 chr15:51854163 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.3 -0.32 9.35e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1994135 0.630 rs11052760 chr12:33724949 A/T cg26384229 chr12:38710491 ALG10B 0.48 6.45 0.33 3.84e-10 Resting heart rate; LIHC cis rs727505 1.000 rs66922607 chr7:124512555 T/A cg23710748 chr7:124431027 NA -0.32 -5.71 -0.3 2.44e-8 Lewy body disease; LIHC cis rs9929218 0.906 rs4783565 chr16:68750190 G/A cg01231543 chr16:68741748 NA 0.39 6.09 0.31 2.99e-9 Colorectal cancer; LIHC cis rs3806843 0.868 rs2262573 chr5:140123627 T/A cg26395211 chr5:140044315 WDR55 0.38 5.77 0.3 1.8e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg18654377 chr3:49208889 KLHDC8B -0.53 -6.25 -0.32 1.2e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06466203 chr10:89623360 PTEN;KILLIN 0.38 6.5 0.33 2.78e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2108622 0.727 rs62106156 chr19:15980424 C/T cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.73e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs916888 0.821 rs199504 chr17:44861003 C/T cg22968622 chr17:43663579 NA -1.2 -13.38 -0.59 4.14e-33 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs651907 0.535 rs12633089 chr3:101528763 C/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg00750074 chr16:89608354 SPG7 -0.51 -8.16 -0.4 6.62e-15 Multiple myeloma (IgH translocation); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg04486506 chr20:62577863 UCKL1 0.4 6.22 0.32 1.49e-9 Alopecia areata; LIHC cis rs9611565 0.649 rs2064189 chr22:42127999 A/G cg03806693 chr22:41940476 POLR3H 0.77 8.64 0.42 2.17e-16 Vitiligo; LIHC cis rs2243480 0.901 rs35823062 chr7:65965821 A/G cg05590025 chr7:65112418 INTS4L2 -0.55 -5.98 -0.31 5.61e-9 Diabetic kidney disease; LIHC cis rs477692 0.905 rs555545 chr10:131411586 G/A cg19680672 chr10:131412579 MGMT -0.42 -6.59 -0.34 1.67e-10 Response to temozolomide; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20859525 chr6:80714300 TTK 0.53 7.5 0.38 5.46e-13 Pancreatic cancer; LIHC trans rs62103177 0.810 rs62103192 chr18:77629050 A/T cg05926928 chr17:57297772 GDPD1 1.1 11.26 0.52 3.23e-25 Opioid sensitivity; LIHC cis rs2637266 0.935 rs2583050 chr10:78403615 C/T cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs10789491 1.000 rs1258061 chr1:47105000 G/A cg15501359 chr1:47185051 KIAA0494 -0.78 -10.63 -0.5 5.23e-23 Response to hepatitis C treatment; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg24842223 chr10:1129728 WDR37 -0.38 -6.11 -0.31 2.74e-9 Calcium levels; LIHC cis rs9420 0.961 rs7949841 chr11:57524700 G/C cg19752551 chr11:57585705 CTNND1 -0.51 -7.17 -0.36 4.8e-12 Schizophrenia; LIHC cis rs7085104 0.572 rs284856 chr10:104574329 A/T cg15744005 chr10:104629667 AS3MT 0.38 8.17 0.4 5.87e-15 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs10916814 0.959 rs2101731 chr1:20901922 G/A cg24502330 chr1:20914028 CDA -0.28 -5.86 -0.3 1.07e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7250872 0.606 rs12985022 chr19:1825401 A/G cg18850929 chr19:1828978 REXO1 0.39 6.25 0.32 1.24e-9 Bipolar disorder; LIHC cis rs10838687 0.867 rs2633082 chr11:47248050 C/G cg26139080 chr11:47293733 MADD 0.42 6.01 0.31 4.67e-9 Proinsulin levels; LIHC cis rs2645694 0.533 rs2645674 chr4:77818202 T/C cg06046430 chr4:77819534 ANKRD56 0.49 6.51 0.33 2.71e-10 Emphysema distribution in smoking; LIHC cis rs4919087 0.590 rs2861877 chr10:99053316 C/A cg25902810 chr10:99078978 FRAT1 -0.63 -6.98 -0.35 1.57e-11 Monocyte count; LIHC cis rs2273156 0.929 rs8017225 chr14:35470049 G/A cg16230307 chr14:35515116 FAM177A1 -0.4 -5.87 -0.3 1.05e-8 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs6754311 0.731 rs745500 chr2:136583192 G/A cg07169764 chr2:136633963 MCM6 -0.67 -10.02 -0.48 6.84e-21 Mosquito bite size; LIHC trans rs1814175 0.586 rs2866862 chr11:49954588 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.83 0.35 3.93e-11 Height; LIHC cis rs9910055 0.529 rs400460 chr17:42182770 A/G cg19774624 chr17:42201019 HDAC5 0.46 5.79 0.3 1.6e-8 Total body bone mineral density; LIHC cis rs875971 0.545 rs801199 chr7:66025273 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.79 -0.34 4.93e-11 Aortic root size; LIHC cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg24642844 chr7:1081250 C7orf50 -0.91 -8.95 -0.44 2.36e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9341808 0.586 rs3805869 chr6:81045917 T/C cg08355045 chr6:80787529 NA 0.34 6.83 0.35 3.92e-11 Sitting height ratio; LIHC cis rs11098499 0.863 rs11731756 chr4:120478696 T/G cg09307838 chr4:120376055 NA 0.75 11.33 0.52 1.79e-25 Corneal astigmatism; LIHC trans rs801193 0.935 rs2659899 chr7:66186721 A/G cg26939375 chr7:64535504 NA 0.42 6.75 0.34 6.45e-11 Aortic root size; LIHC cis rs826838 1.000 rs11183747 chr12:38822595 A/G cg13010199 chr12:38710504 ALG10B -0.65 -7.8 -0.39 7.55e-14 Heart rate; LIHC cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg11301795 chr4:187892539 NA 0.26 6.68 0.34 9.55e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7635838 0.819 rs2454482 chr3:11534031 C/T cg00170343 chr3:11313890 ATG7 0.4 6.19 0.32 1.68e-9 HDL cholesterol; LIHC cis rs11628318 0.614 rs10782496 chr14:103079725 C/G cg12046867 chr14:103022105 NA -0.43 -6.78 -0.34 5.22e-11 Platelet count; LIHC cis rs7945718 0.621 rs11022463 chr11:12685395 T/C cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs10088262 0.629 rs7827665 chr8:124804190 G/A cg20713898 chr8:124780851 FAM91A1 -0.55 -7.56 -0.38 3.78e-13 Pancreatic cancer; LIHC cis rs1707322 0.682 rs10890335 chr1:46100394 G/C cg06784218 chr1:46089804 CCDC17 0.42 7.67 0.38 1.79e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg08280861 chr8:58055591 NA 0.49 6.05 0.31 3.9e-9 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg00149659 chr3:10157352 C3orf10 0.61 6.71 0.34 7.86e-11 Alzheimer's disease; LIHC cis rs9905704 0.624 rs6503891 chr17:57065924 A/C cg05425664 chr17:57184151 TRIM37 -0.43 -5.85 -0.3 1.18e-8 Testicular germ cell tumor; LIHC cis rs7917772 0.539 rs12572775 chr10:104285594 A/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -7.97 -0.4 2.4e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg10295955 chr4:187884368 NA -0.96 -22.67 -0.77 4.29e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs4409675 0.576 rs6598912 chr1:28233289 C/T cg23691781 chr1:28212827 C1orf38 0.31 7.56 0.38 3.64e-13 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23337289 chr2:27603239 ZNF513 0.42 6.34 0.32 7.3e-10 Pancreatic cancer; LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.29 -0.32 9.81e-10 Menopause (age at onset); LIHC cis rs798554 0.567 rs2527695 chr7:2858267 T/G cg13628971 chr7:2884303 GNA12 0.44 7.01 0.35 1.24e-11 Height; LIHC trans rs10411161 0.810 rs17778661 chr19:52383288 C/G cg22319618 chr22:45562946 NUP50 -0.6 -7.02 -0.35 1.24e-11 Breast cancer; LIHC cis rs6942756 0.747 rs692432 chr7:129113287 G/A cg02491457 chr7:128862824 NA -0.55 -8.44 -0.42 8.92e-16 White matter hyperintensity burden; LIHC cis rs67311347 0.822 rs9826847 chr3:40345312 A/T cg18306943 chr3:40428807 ENTPD3 0.35 5.85 0.3 1.13e-8 Renal cell carcinoma; LIHC trans rs11174436 0.571 rs11174401 chr12:62655061 T/A cg14249155 chr9:124976040 LHX6 0.46 6.09 0.31 3.03e-9 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs9467160 0.559 rs2753911 chr6:24442288 C/T cg20631270 chr6:24437470 GPLD1 0.5 7.6 0.38 2.89e-13 Liver enzyme levels; LIHC trans rs916888 0.821 rs199513 chr17:44856932 A/G cg22968622 chr17:43663579 NA -1.02 -11.4 -0.52 9.83e-26 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg09417038 chr21:47716443 C21orf57 -0.5 -7.27 -0.37 2.49e-12 Testicular germ cell tumor; LIHC cis rs9486719 1.000 rs13210597 chr6:96969694 C/A cg06623918 chr6:96969491 KIAA0776 -0.71 -7.19 -0.36 4.2e-12 Migraine;Coronary artery disease; LIHC cis rs12744310 0.778 rs61477144 chr1:41771793 A/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs8192282 0.739 rs9427415 chr1:154508437 A/T cg16683920 chr1:154474344 TDRD10;SHE 0.45 5.72 0.3 2.34e-8 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); LIHC cis rs2991971 0.934 rs11211129 chr1:45983080 C/T cg24296786 chr1:45957014 TESK2 0.54 8.03 0.4 1.64e-14 High light scatter reticulocyte count; LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg11598736 chr3:195384522 SDHAP2 0.71 8.55 0.42 4.15e-16 Lung disease severity in cystic fibrosis; LIHC cis rs2066819 1.000 rs2306694 chr12:56680636 C/T cg26714650 chr12:56694279 CS 1.35 13.72 0.6 1.87e-34 Psoriasis vulgaris; LIHC cis rs1534166 0.601 rs13324779 chr3:133510413 G/A cg12373951 chr3:133503437 NA -0.49 -6.89 -0.35 2.61e-11 Alcohol consumption (transferrin glycosylation); LIHC cis rs9733 0.596 rs3087960 chr1:150620569 C/G cg13175981 chr1:150552382 MCL1 -0.42 -5.83 -0.3 1.25e-8 Tonsillectomy; LIHC cis rs798554 0.959 rs798558 chr7:2758935 T/G cg19717773 chr7:2847554 GNA12 -0.39 -6.04 -0.31 4.07e-9 Height; LIHC cis rs2274273 0.840 rs10467798 chr14:55724927 C/T cg01864836 chr14:55583639 NA -0.41 -7.86 -0.39 4.89e-14 Protein biomarker; LIHC cis rs4268898 0.931 rs55642516 chr2:24502305 A/G cg06627628 chr2:24431161 ITSN2 -0.56 -8.12 -0.4 8.28e-15 Asthma; LIHC trans rs2235573 0.551 rs139893 chr22:38393608 G/A cg19894588 chr14:64061835 NA 0.46 6.08 0.31 3.21e-9 Glioblastoma;Glioma; LIHC cis rs8044995 0.501 rs55793998 chr16:68378985 G/T cg05110241 chr16:68378359 PRMT7 -0.86 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs858239 0.539 rs6965833 chr7:23192366 T/C cg23682824 chr7:23144976 KLHL7 0.4 5.93 0.31 7.21e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs4141404 0.851 rs5749222 chr22:31556759 C/G cg07713946 chr22:31675144 LIMK2 -0.28 -6.16 -0.32 2.05e-9 Paclitaxel-induced neuropathy; LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs7712401 0.791 rs154507 chr5:122200907 C/G cg18764291 chr5:122110994 SNX2 -0.36 -6.12 -0.31 2.54e-9 Mean platelet volume; LIHC trans rs637571 0.522 rs491973 chr11:65727301 A/G cg17712092 chr4:129076599 LARP1B 0.74 12.98 0.57 1.38e-31 Eosinophil percentage of white cells; LIHC cis rs2228479 0.850 rs2302162 chr16:89845287 A/G cg04013166 chr16:89971882 TCF25 0.49 6.01 0.31 4.68e-9 Skin colour saturation; LIHC cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg17328964 chr8:145687451 CYHR1 0.55 9.66 0.46 1.1e-19 Age at first birth; LIHC cis rs10540 1.000 rs61877775 chr11:521462 C/T cg03352830 chr11:487213 PTDSS2 0.81 6.12 0.31 2.5e-9 Body mass index; LIHC cis rs7772486 0.764 rs2265468 chr6:146218346 A/C cg13319975 chr6:146136371 FBXO30 -0.4 -6.38 -0.33 5.9e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17433710 0.543 rs12024691 chr1:162654790 G/A cg01063088 chr1:162760584 HSD17B7 0.43 5.97 0.31 6.08e-9 Dupuytren's disease; LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg06558623 chr16:89946397 TCF25 0.98 15.17 0.63 4.19e-40 Skin colour saturation; LIHC trans rs6489882 0.671 rs4767028 chr12:113359188 A/G cg10175203 chr3:128143634 NA 0.39 6.4 0.33 5.08e-10 Chronic lymphocytic leukemia; LIHC cis rs861318 0.702 rs3754460 chr1:159006846 T/C cg11003133 chr1:159046391 AIM2 -0.35 -6.72 -0.34 7.84e-11 Obesity-related traits; LIHC trans rs116095464 0.558 rs3213838 chr5:223890 G/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg07424592 chr7:64974309 NA -0.8 -9.28 -0.45 1.96e-18 Diabetic kidney disease; LIHC cis rs875971 0.862 rs949930 chr7:65766822 C/G cg18252515 chr7:66147081 NA 0.44 6.34 0.32 7.48e-10 Aortic root size; LIHC trans rs7849581 1 rs7849581 chr9:9924724 A/G cg01301323 chr12:77252588 CSRP2 0.52 6.1 0.31 2.85e-9 Myopia (pathological); LIHC cis rs12594515 0.935 rs8042519 chr15:45996341 G/C cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC cis rs2279817 0.863 rs34820073 chr1:18010535 C/T cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.76 -0.39 9.68e-14 Neuroticism; LIHC cis rs4862750 0.872 rs4862748 chr4:187877388 C/T cg11301795 chr4:187892539 NA 0.21 5.76 0.3 1.92e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.820 rs28394116 chr4:120524283 T/G cg09307838 chr4:120376055 NA 0.73 11.07 0.51 1.54e-24 Corneal astigmatism; LIHC cis rs1580019 0.587 rs6951955 chr7:32548761 A/T cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.12 0.31 2.56e-9 Cognitive ability; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25454546 chr8:17781589 PCM1 0.46 6.46 0.33 3.54e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg22963979 chr7:1858916 MAD1L1 -0.44 -7.03 -0.36 1.16e-11 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg11764359 chr7:65958608 NA 0.56 5.74 0.3 2.04e-8 Diabetic kidney disease; LIHC cis rs4843747 0.697 rs72818533 chr16:88073841 G/A cg00677901 chr16:88017247 BANP 0.58 8.47 0.42 7.32e-16 Menopause (age at onset); LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg02290350 chr8:58132656 NA 0.49 10.6 0.5 6.68e-23 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg07424592 chr7:64974309 NA -0.8 -9.23 -0.45 2.9e-18 Diabetic kidney disease; LIHC cis rs79057730 0.599 rs9458 chr7:825494 A/G cg11064039 chr7:766100 PRKAR1B;HEATR2 -0.83 -9.59 -0.46 1.86e-19 Initial pursuit acceleration; LIHC cis rs7552404 0.731 rs1770887 chr1:76401812 A/G cg10523679 chr1:76189770 ACADM -0.59 -6.82 -0.35 4.11e-11 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20444381 chr8:109456000 TTC35 -0.44 -6.38 -0.33 5.74e-10 Systolic blood pressure; LIHC cis rs1129187 0.748 rs6458312 chr6:42904274 G/T cg21280719 chr6:42927975 GNMT -0.31 -7.26 -0.37 2.69e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs13108904 0.517 rs13134568 chr4:1334289 G/A cg13395646 chr4:1353034 KIAA1530 -0.82 -12.49 -0.56 9.48e-30 Obesity-related traits; LIHC cis rs9394159 0.583 rs6457738 chr6:33617464 C/T cg14003231 chr6:33640908 ITPR3 -0.27 -6.09 -0.31 3.05e-9 Graves' disease; LIHC cis rs7089973 0.604 rs11196952 chr10:116607592 G/A cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4407350 1.000 rs5765745 chr22:44924894 A/G cg26276947 chr22:44892394 LDOC1L 0.33 6.05 0.31 3.77e-9 Intelligence (multi-trait analysis); LIHC cis rs6540556 0.723 rs7539852 chr1:209898539 A/G cg05527609 chr1:210001259 C1orf107 -0.54 -7.39 -0.37 1.1e-12 Red blood cell count; LIHC cis rs787274 0.850 rs7862183 chr9:115529696 C/T cg13803584 chr9:115635662 SNX30 -0.56 -6.18 -0.32 1.79e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2180341 0.855 rs4308584 chr6:127714874 A/G cg24812749 chr6:127587940 RNF146 0.84 13.13 0.58 3.57e-32 Breast cancer; LIHC cis rs2204008 0.628 rs10876106 chr12:37990767 A/G cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs4660306 1.000 rs2356561 chr1:45980862 T/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.57 -6.83 -0.35 3.93e-11 Homocysteine levels; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg03874509 chr1:107600012 PRMT6 0.73 11.29 0.52 2.45e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs72781680 0.821 rs72781644 chr2:24209348 T/C cg08917208 chr2:24149416 ATAD2B 0.62 6.25 0.32 1.25e-9 Lymphocyte counts; LIHC cis rs2290416 0.584 rs3816477 chr8:144685271 T/C cg26536354 chr8:144654954 C8orf73 -0.45 -5.81 -0.3 1.45e-8 Attention deficit hyperactivity disorder; LIHC cis rs9818758 0.607 rs73084135 chr3:49272218 A/G cg07636037 chr3:49044803 WDR6 -0.83 -7.1 -0.36 7.41e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs769267 0.831 rs2872878 chr19:19480521 G/C cg26732615 chr19:19648335 CILP2;YJEFN3 -0.4 -5.92 -0.3 7.79e-9 Tonsillectomy; LIHC cis rs11098499 0.909 rs10017335 chr4:120381523 C/G cg09307838 chr4:120376055 NA -0.78 -11.83 -0.54 2.62e-27 Corneal astigmatism; LIHC cis rs72781680 0.898 rs72790310 chr2:24116716 C/T cg08917208 chr2:24149416 ATAD2B 0.84 7.73 0.39 1.21e-13 Lymphocyte counts; LIHC cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg13395646 chr4:1353034 KIAA1530 -0.53 -8.21 -0.41 4.46e-15 Longevity; LIHC cis rs7833986 0.501 rs2976012 chr8:56974343 T/C cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.76 0.43 9.13e-17 Height; LIHC cis rs1775715 0.677 rs2808074 chr10:32179184 A/C cg14930904 chr10:32216787 ARHGAP12 0.36 6.29 0.32 9.98e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs7927771 0.832 rs10769262 chr11:47411581 G/A cg20307385 chr11:47447363 PSMC3 0.45 5.87 0.3 1.02e-8 Subjective well-being; LIHC cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.84 0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs7044106 0.791 rs10984995 chr9:123479210 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.04 0.51 1.88e-24 Hip circumference adjusted for BMI; LIHC cis rs6461049 0.734 rs1558465 chr7:2151398 G/C cg02951883 chr7:2050386 MAD1L1 -0.63 -10.22 -0.48 1.37e-21 Schizophrenia; LIHC cis rs9309711 0.621 rs12993215 chr2:3473727 T/C cg15506890 chr2:3487001 NA -0.54 -8.54 -0.42 4.58e-16 Neurofibrillary tangles; LIHC cis rs921968 0.541 rs7604319 chr2:219538799 A/C cg02176678 chr2:219576539 TTLL4 -0.54 -7.06 -0.36 9.08e-12 Mean corpuscular hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11207507 chr13:80915118 SPRY2 0.44 6.35 0.32 6.93e-10 Pancreatic cancer; LIHC cis rs2282526 0.615 rs463738 chr21:44921166 G/A cg21573476 chr21:45109991 RRP1B 0.53 8.9 0.43 3.43e-17 Mean corpuscular hemoglobin; LIHC cis rs7707921 0.767 rs862245 chr5:81585737 A/C cg15871215 chr5:81402204 ATG10 -0.69 -8.31 -0.41 2.36e-15 Breast cancer; LIHC cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg27297192 chr10:134578999 INPP5A 0.54 7.58 0.38 3.3e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs921968 0.608 rs832817 chr2:219358603 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.65 0.42 2.09e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs9309473 0.848 rs9750915 chr2:73811880 T/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.58 -0.34 1.72e-10 Metabolite levels; LIHC cis rs7223966 0.961 rs17631783 chr17:61687600 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.57 -6.44 -0.33 4e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7607369 0.680 rs533760 chr2:219381405 T/C cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Red blood cell count;Amyotrophic lateral sclerosis; LIHC trans rs7714584 1.000 rs7705542 chr5:150228318 G/A cg20675040 chr8:143813288 C8orf55 0.34 6.13 0.31 2.41e-9 Crohn's disease; LIHC cis rs6545883 0.929 rs7563678 chr2:61741811 C/T cg15711740 chr2:61764176 XPO1 0.43 6.06 0.31 3.53e-9 Tuberculosis; LIHC cis rs4927850 1.000 rs10881564 chr3:195750326 C/T cg12923728 chr3:195709715 SDHAP1 -0.75 -10.71 -0.5 2.88e-23 Pancreatic cancer; LIHC cis rs4759375 0.598 rs11060725 chr12:123399478 G/T cg25930673 chr12:123319894 HIP1R 0.63 7.12 0.36 6.31e-12 HDL cholesterol; LIHC cis rs796364 0.951 rs3098341 chr2:200792498 G/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.27 0.41 2.94e-15 Schizophrenia; LIHC trans rs11098499 0.909 rs1809406 chr4:120377122 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.71 0.46 7.58e-20 Corneal astigmatism; LIHC trans rs2251381 0.750 rs2255055 chr21:30537045 C/T cg14791747 chr16:20752902 THUMPD1 -0.47 -6.33 -0.32 7.66e-10 Selective IgA deficiency; LIHC cis rs965469 0.779 rs6037543 chr20:3289505 A/G cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs950169 0.580 rs11636189 chr15:85193554 G/A cg03959625 chr15:84868606 LOC388152 0.45 6.35 0.32 7.05e-10 Schizophrenia; LIHC cis rs288342 0.832 rs208393 chr2:183649428 C/T cg02625481 chr2:183667124 NA -0.29 -5.95 -0.31 6.48e-9 Recurrent major depressive disorder; LIHC cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg07061783 chr6:25882402 NA -0.47 -6.48 -0.33 3.29e-10 Blood metabolite levels; LIHC cis rs10504073 0.647 rs10105794 chr8:50012793 G/C cg00325661 chr8:49890786 NA 0.31 7.19 0.36 4.24e-12 Blood metabolite ratios; LIHC cis rs600626 0.529 rs10899113 chr11:75468464 T/A cg24262691 chr11:75473276 NA 0.39 5.82 0.3 1.36e-8 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs10751667 0.600 rs1128419 chr11:1010750 G/A ch.11.42038R chr11:967971 AP2A2 0.6 11.04 0.51 1.88e-24 Alzheimer's disease (late onset); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg13572638 chr1:227173653 CABC1 0.42 6.09 0.31 3.11e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs7586673 0.930 rs7591506 chr2:161960925 T/G cg21518248 chr2:162101506 NA 0.42 6.26 0.32 1.16e-9 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg08888203 chr3:10149979 C3orf24 0.62 6.93 0.35 2.15e-11 Alzheimer's disease; LIHC cis rs16828019 0.929 rs111309254 chr1:41736000 A/G cg03387723 chr1:41708464 SCMH1 -0.44 -7.17 -0.36 4.74e-12 Intelligence (multi-trait analysis); LIHC cis rs4906332 0.811 rs2021965 chr14:103997248 C/A cg04998671 chr14:104000505 TRMT61A 0.59 7.86 0.39 5.15e-14 Coronary artery disease; LIHC trans rs7980799 0.682 rs1384599 chr12:33624579 G/A cg26384229 chr12:38710491 ALG10B -0.45 -6.1 -0.31 2.86e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06438815 chr21:46292710 PTTG1IP 0.37 6.12 0.31 2.53e-9 Cognitive function; LIHC cis rs7552404 0.731 rs12090849 chr1:76400261 A/G cg10523679 chr1:76189770 ACADM 0.56 7.24 0.36 3.06e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1461503 0.966 rs10892937 chr11:122841904 T/C cg14473756 chr11:122847823 NA -0.37 -6.74 -0.34 6.82e-11 Menarche (age at onset); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg03533979 chr22:47097306 CERK 0.39 6.34 0.32 7.36e-10 Alopecia areata; LIHC cis rs7208859 0.673 rs11657270 chr17:29214387 A/G cg13385521 chr17:29058706 SUZ12P 0.82 7.96 0.4 2.57e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11207507 chr13:80915118 SPRY2 0.4 6.27 0.32 1.06e-9 Cognitive function; LIHC cis rs1538970 1.000 rs7417107 chr1:45831915 G/C cg05343316 chr1:45956843 TESK2 0.54 8.12 0.4 8.47e-15 Platelet count; LIHC cis rs2286503 0.839 rs2270105 chr7:22862467 G/A cg11367502 chr7:22862612 TOMM7 0.45 7.51 0.38 5.08e-13 Fibrinogen; LIHC cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg02359409 chr6:42947317 PEX6 -0.48 -6.8 -0.35 4.69e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7044106 0.708 rs959558 chr9:123368911 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.71 11.13 0.52 9.28e-25 Hip circumference adjusted for BMI; LIHC cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg23758822 chr17:41437982 NA 0.93 17.47 0.69 2.79e-49 Menopause (age at onset); LIHC cis rs7582180 0.629 rs74177696 chr2:100938481 C/G cg14675211 chr2:100938903 LONRF2 0.53 8.29 0.41 2.59e-15 Intelligence (multi-trait analysis); LIHC cis rs9287719 0.967 rs1541573 chr2:10773385 T/G cg02829992 chr2:10710499 NA -0.38 -6.05 -0.31 3.75e-9 Prostate cancer; LIHC cis rs34375054 0.641 rs34624329 chr12:125608028 T/G cg25124228 chr12:125621409 AACS -0.39 -6.62 -0.34 1.35e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs10463316 0.779 rs6861968 chr5:150817725 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -6.21 -0.32 1.49e-9 Metabolite levels (Pyroglutamine); LIHC cis rs7818688 0.697 rs76215523 chr8:95987015 T/C cg16049864 chr8:95962084 TP53INP1 0.59 6.42 0.33 4.5e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4820294 0.669 rs7287358 chr22:38054403 A/G cg26138144 chr22:38071188 LGALS1 0.42 7.83 0.39 6.21e-14 Fat distribution (HIV); LIHC cis rs9911578 0.935 rs304261 chr17:56813782 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.91 0.7 4.42e-51 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.765 rs8071576 chr17:28188554 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 14.19 0.61 3.04e-36 Coffee consumption (cups per day); LIHC cis rs9916302 0.904 rs9894500 chr17:37515735 G/C cg00129232 chr17:37814104 STARD3 0.38 6.11 0.31 2.67e-9 Glomerular filtration rate (creatinine); LIHC cis rs11675119 0.513 rs9752321 chr2:3494374 A/G cg15506890 chr2:3487001 NA -0.44 -6.6 -0.34 1.58e-10 Neurofibrillary tangles; LIHC cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg08219700 chr8:58056026 NA 0.53 6.36 0.33 6.6e-10 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.503 rs12702047 chr7:1132720 G/A cg02733842 chr7:1102375 C7orf50 -0.76 -7.63 -0.38 2.28e-13 Bronchopulmonary dysplasia; LIHC cis rs9911578 0.935 rs7216698 chr17:57007495 G/A cg12560992 chr17:57184187 TRIM37 0.9 15.98 0.65 2.55e-43 Intelligence (multi-trait analysis); LIHC cis rs74233809 1.000 rs12217501 chr10:104851889 T/C cg03493300 chr10:104813866 CNNM2 0.46 6.11 0.31 2.71e-9 Birth weight; LIHC cis rs34779708 1.000 rs12769189 chr10:35399668 A/G cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11122272 0.735 rs2246645 chr1:231497393 T/G cg06096015 chr1:231504339 EGLN1 0.51 9.39 0.45 8.59e-19 Hemoglobin concentration; LIHC cis rs61990749 0.597 rs11624101 chr14:78138059 G/A cg21497246 chr14:78225524 SNW1;C14orf178 0.49 7.44 0.37 8.42e-13 Fibroblast growth factor basic levels; LIHC cis rs651907 0.535 rs61396602 chr3:101509046 T/C cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.84 -0.3 1.22e-8 Colorectal cancer; LIHC cis rs3806843 1.000 rs1030165 chr5:140185448 G/A cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9303401 0.659 rs35797125 chr17:56736547 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg27432699 chr2:27873401 GPN1 -0.52 -7.47 -0.37 6.89e-13 Total body bone mineral density; LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg02475777 chr4:1388615 CRIPAK 0.53 7.88 0.39 4.46e-14 Longevity; LIHC cis rs9733 0.544 rs2867302 chr1:150653650 T/C cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Tonsillectomy; LIHC cis rs7546668 1.000 rs6429746 chr1:15815579 A/G cg11706911 chr1:15910989 AGMAT -0.39 -5.82 -0.3 1.39e-8 Glomerular filtration rate (creatinine); LIHC cis rs712039 0.652 rs8069062 chr17:35829306 C/T cg16670864 chr17:35848621 DUSP14 0.34 5.73 0.3 2.19e-8 Tuberculosis; LIHC cis rs80282103 0.867 rs13377037 chr10:1068639 C/T cg08668510 chr10:1095578 IDI1 0.67 7.05 0.36 9.86e-12 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04232466 chr8:21988724 HR 0.45 6.58 0.34 1.72e-10 Pancreatic cancer; LIHC trans rs9747201 0.926 rs8065606 chr17:80063526 G/A cg07393940 chr7:158741817 NA -0.56 -6.59 -0.34 1.66e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1728785 0.681 rs4783649 chr16:68558467 G/A cg02972257 chr16:68554789 NA 0.61 6.45 0.33 3.74e-10 Ulcerative colitis; LIHC cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg06238570 chr21:40685208 BRWD1 0.6 7.07 0.36 8.73e-12 Cognitive function; LIHC cis rs7615952 0.932 rs11922218 chr3:125631289 C/T cg05084668 chr3:125655381 ALG1L -0.57 -8.14 -0.4 7.19e-15 Blood pressure (smoking interaction); LIHC cis rs7551222 0.752 rs4951400 chr1:204534571 C/G cg20240347 chr1:204465584 NA -0.34 -7.13 -0.36 5.89e-12 Schizophrenia; LIHC cis rs2637030 0.559 rs31303 chr5:52942197 C/T cg06476337 chr5:52856530 NDUFS4 -0.42 -6.73 -0.34 7.19e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs10916814 0.632 rs6691041 chr1:20898650 A/G cg24502330 chr1:20914028 CDA -0.3 -6.7 -0.34 8.63e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg12463550 chr7:65579703 CRCP -0.73 -7.64 -0.38 2.26e-13 Diabetic kidney disease; LIHC cis rs6952808 0.534 rs1113736 chr7:1992992 T/C cg14004847 chr7:1930337 MAD1L1 -0.43 -6.4 -0.33 5.07e-10 Bipolar disorder and schizophrenia; LIHC cis rs72781680 0.533 rs34668726 chr2:23895901 C/G cg08917208 chr2:24149416 ATAD2B 0.92 7.8 0.39 7.56e-14 Lymphocyte counts; LIHC cis rs909002 0.830 rs7542583 chr1:32110813 A/G cg13919466 chr1:32135498 COL16A1 -0.36 -6.65 -0.34 1.18e-10 Intelligence (multi-trait analysis); LIHC cis rs870825 0.860 rs10015194 chr4:185598925 C/T cg04058563 chr4:185651563 MLF1IP 0.78 6.95 0.35 1.83e-11 Blood protein levels; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg09074113 chr2:20870087 GDF7 -0.52 -10.35 -0.49 5.22e-22 Abdominal aortic aneurysm; LIHC cis rs709400 0.659 rs3825566 chr14:103852725 C/T cg26031613 chr14:104095156 KLC1 -0.73 -9.24 -0.45 2.61e-18 Body mass index; LIHC cis rs151349 1.000 rs151344 chr20:57585301 A/G cg23907860 chr20:57583709 CTSZ -0.42 -7.01 -0.35 1.27e-11 Platelet distribution width; LIHC trans rs1974653 0.813 rs1974652 chr22:20134147 A/G cg20152630 chr19:46405944 MYPOP 0.51 6.64 0.34 1.25e-10 Schizophrenia; LIHC trans rs1005277 0.579 rs2474608 chr10:38457109 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs738321 0.725 rs4821747 chr22:38538856 T/C cg25457927 chr22:38595422 NA -0.32 -7.34 -0.37 1.52e-12 Breast cancer; LIHC cis rs6502050 0.835 rs8071737 chr17:80117537 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs7572733 0.534 rs1607375 chr2:198800387 C/T cg00792783 chr2:198669748 PLCL1 0.46 6.86 0.35 3.19e-11 Dermatomyositis; LIHC cis rs9303401 0.538 rs12603174 chr17:56489279 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.84 11.41 0.52 9.39e-26 Cognitive test performance; LIHC cis rs12701220 0.744 rs35588238 chr7:1012006 G/A cg00990874 chr7:1149470 C7orf50 -0.43 -6.44 -0.33 3.93e-10 Bronchopulmonary dysplasia; LIHC cis rs28735056 0.967 rs8091497 chr18:77632565 G/A cg20368463 chr18:77673604 PQLC1 -0.38 -6.72 -0.34 7.5e-11 Schizophrenia; LIHC cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg19729930 chr2:74357872 NA 0.84 18.46 0.71 2.84e-53 Gestational age at birth (maternal effect); LIHC cis rs344364 0.511 rs2982453 chr16:1949520 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs918629 0.716 rs3777178 chr5:95273915 G/C cg10483112 chr5:95245456 ELL2 -0.36 -6.28 -0.32 1.04e-9 IgG glycosylation; LIHC cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg03517284 chr6:25882590 NA -0.64 -9.17 -0.44 4.62e-18 Blood metabolite levels; LIHC trans rs3812049 0.784 rs2250127 chr5:127388844 G/A cg16011800 chr17:1958478 HIC1 0.52 7.31 0.37 1.96e-12 Lymphocyte counts;Red cell distribution width; LIHC cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg21724239 chr8:58056113 NA 0.56 7.07 0.36 8.9e-12 Developmental language disorder (linguistic errors); LIHC cis rs7044106 0.762 rs7849566 chr9:123460769 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.99 0.4 2.14e-14 Hip circumference adjusted for BMI; LIHC cis rs2637266 1.000 rs7897348 chr10:78359620 G/A cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.14e-8 Pulmonary function; LIHC cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg19723775 chr5:179050963 HNRNPH1 0.37 5.89 0.3 9.48e-9 Lung cancer; LIHC cis rs1577917 0.959 rs34258068 chr6:86679449 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.08 -0.48 4.45e-21 Response to antipsychotic treatment; LIHC cis rs600231 0.706 rs11227221 chr11:65319265 T/C cg17120908 chr11:65337727 SSSCA1 0.46 6.52 0.33 2.53e-10 Bone mineral density; LIHC cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg21724239 chr8:58056113 NA 0.57 7.54 0.38 4.31e-13 Developmental language disorder (linguistic errors); LIHC cis rs903552 1.000 rs12906575 chr15:102003617 G/A cg25677261 chr15:102009856 PCSK6 -0.44 -5.99 -0.31 5.4e-9 Diabetic kidney disease; LIHC cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.95 9.69 0.46 8.64e-20 Platelet count; LIHC cis rs7945705 0.840 rs10840136 chr11:8885024 C/T cg12365402 chr11:9010492 NRIP3 -0.26 -6.65 -0.34 1.17e-10 Hemoglobin concentration; LIHC cis rs2795502 0.938 rs3121324 chr10:43379515 C/T cg20628663 chr10:43360327 NA 0.46 7.12 0.36 6.45e-12 Blood protein levels; LIHC cis rs3849570 0.925 rs6799080 chr3:81905591 G/A cg07356753 chr3:81810745 GBE1 -0.55 -8.63 -0.42 2.28e-16 Waist circumference;Body mass index; LIHC cis rs10779751 1.000 rs6670821 chr1:11308762 T/C cg08854313 chr1:11322531 MTOR 0.82 11.65 0.53 1.17e-26 Body mass index; LIHC cis rs11971779 0.680 rs4732379 chr7:139122814 T/C cg07862535 chr7:139043722 LUC7L2 0.59 9.7 0.46 8.15e-20 Diisocyanate-induced asthma; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg05064044 chr6:292385 DUSP22 -0.54 -7.11 -0.36 6.83e-12 Menopause (age at onset); LIHC cis rs7122539 0.646 rs569818 chr11:66570749 G/A cg24851651 chr11:66362959 CCS 0.36 6.43 0.33 4.21e-10 HIV-1 susceptibility; LIHC cis rs12142240 0.698 rs1053627 chr1:46827728 A/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs7249142 0.527 rs12975096 chr19:19279409 G/T cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.47 -7.82 -0.39 6.84e-14 IgG glycosylation; LIHC cis rs2066819 1.000 rs2643626 chr12:56726518 C/T cg26714650 chr12:56694279 CS 1.25 15.27 0.64 1.6e-40 Psoriasis vulgaris; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg20786246 chr2:72377174 NA -0.5 -6.3 -0.32 9.39e-10 Facial morphology (factor 20); LIHC cis rs6500602 1.000 rs6500602 chr16:4497451 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.45 6.73 0.34 7.32e-11 Schizophrenia; LIHC cis rs4332037 0.802 rs73048106 chr7:1929019 G/T cg23422044 chr7:1970798 MAD1L1 -0.66 -7.47 -0.37 6.67e-13 Bipolar disorder; LIHC cis rs4253772 0.530 rs9615362 chr22:46795141 A/C cg18190219 chr22:46762943 CELSR1 0.72 6.69 0.34 9.02e-11 LDL cholesterol;Cholesterol, total; LIHC cis rs68170813 0.559 rs76208112 chr7:106964222 C/T cg02696742 chr7:106810147 HBP1 -0.5 -5.86 -0.3 1.08e-8 Coronary artery disease; LIHC cis rs151997 0.893 rs27607 chr5:50228977 A/G cg06027927 chr5:50259733 NA -0.57 -7.68 -0.38 1.69e-13 Callous-unemotional behaviour; LIHC cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.46 10.14 0.48 2.72e-21 Calcium levels; LIHC cis rs4474465 1.000 rs4945277 chr11:78166967 C/T cg02023728 chr11:77925099 USP35 0.32 5.85 0.3 1.14e-8 Alzheimer's disease (survival time); LIHC cis rs4595586 0.525 rs11611705 chr12:39426828 C/T cg26384229 chr12:38710491 ALG10B 0.5 6.0 0.31 4.92e-9 Morning vs. evening chronotype; LIHC cis rs2760061 0.598 rs673726 chr1:228120173 T/C cg02753203 chr1:228287806 NA -0.49 -7.87 -0.39 4.68e-14 Diastolic blood pressure; LIHC cis rs12701220 0.655 rs34696066 chr7:1140919 C/T cg26769984 chr7:1090371 C7orf50 0.46 5.73 0.3 2.21e-8 Bronchopulmonary dysplasia; LIHC cis rs35306767 0.953 rs10904581 chr10:964685 A/T cg26597838 chr10:835615 NA 0.97 11.78 0.54 4.14e-27 Eosinophil percentage of granulocytes; LIHC cis rs7619427 0.544 rs58289556 chr3:44034726 C/T cg24966902 chr3:44043705 NA 0.53 8.23 0.41 4.07e-15 Schizophrenia; LIHC cis rs7659604 1.000 rs28618203 chr4:122663935 T/C cg19748678 chr4:122722346 EXOSC9 0.38 6.45 0.33 3.86e-10 Type 2 diabetes; LIHC cis rs1577917 0.958 rs12216074 chr6:86520002 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.15 -0.32 2.2e-9 Response to antipsychotic treatment; LIHC cis rs7937682 0.889 rs11213971 chr11:111529829 A/G cg09085632 chr11:111637200 PPP2R1B -1.06 -13.58 -0.59 6.77e-34 Primary sclerosing cholangitis; LIHC cis rs8067545 0.750 rs4005937 chr17:19959828 A/C cg13482628 chr17:19912719 NA 0.49 8.33 0.41 2e-15 Schizophrenia; LIHC cis rs4820539 1.000 rs4822362 chr22:23482744 C/A cg21100191 chr22:23484243 RTDR1 0.91 17.01 0.68 1.88e-47 Bone mineral density; LIHC cis rs6542838 0.609 rs13028500 chr2:99528296 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.24 -0.32 1.29e-9 Fear of minor pain; LIHC cis rs2303759 0.914 rs2288481 chr19:49878196 G/A cg24324837 chr19:49891574 CCDC155 0.38 5.77 0.3 1.77e-8 Multiple sclerosis; LIHC cis rs13161895 0.646 rs75894617 chr5:179499854 G/C cg02702477 chr5:179499311 RNF130 0.96 11.78 0.54 4.13e-27 LDL cholesterol; LIHC cis rs11673344 0.864 rs8106386 chr19:37503899 C/T cg27390819 chr19:37464633 NA 0.5 6.1 0.31 2.87e-9 Obesity-related traits; LIHC cis rs611744 0.647 rs615126 chr8:109247619 C/T cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs367615 0.918 rs10051855 chr5:108859958 G/A cg17395555 chr5:108820864 NA 0.35 7.26 0.37 2.69e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.8 -0.57 6.21e-31 Alzheimer's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13240253 chr3:71245529 FOXP1 0.45 7.25 0.36 2.86e-12 Longevity; LIHC cis rs1000083 0.748 rs3108530 chr5:96628139 C/G ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs7818688 0.653 rs16893774 chr8:95895976 C/G cg16049864 chr8:95962084 TP53INP1 -0.52 -6.04 -0.31 4.07e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs116095464 0.558 rs6555055 chr5:226160 A/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs17818399 0.684 rs62134759 chr2:46791849 G/A cg02822958 chr2:46747628 ATP6V1E2 0.51 7.42 0.37 9.47e-13 Height; LIHC trans rs1941687 0.509 rs6507060 chr18:31322278 C/T cg27147174 chr7:100797783 AP1S1 0.45 6.22 0.32 1.48e-9 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs644799 0.965 rs499076 chr11:95546341 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.14 0.68 5.42e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4728302 0.869 rs2059298 chr7:133603245 C/G cg10665199 chr7:133106180 EXOC4 0.39 6.82 0.35 4.1e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs533581 0.708 rs2968475 chr16:88976663 C/G cg03970086 chr16:88974840 CBFA2T3 0.33 6.37 0.33 6.17e-10 Social autistic-like traits; LIHC cis rs2710642 0.962 rs6545972 chr2:63084682 G/A cg17519650 chr2:63277830 OTX1 0.44 7.01 0.35 1.28e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.27 -0.55 6.47e-29 Alzheimer's disease; LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg00800038 chr16:89945340 TCF25 -0.7 -11.35 -0.52 1.51e-25 Skin colour saturation; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15725733 chr2:236949415 AGAP1 -0.34 -6.31 -0.32 8.51e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2180341 1.000 rs6569486 chr6:127708424 A/C cg27446573 chr6:127587934 RNF146 1.03 16.27 0.66 1.75e-44 Breast cancer; LIHC cis rs9911578 0.967 rs4076229 chr17:56937256 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.82 0.69 1.04e-50 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg03517284 chr6:25882590 NA -0.64 -8.25 -0.41 3.51e-15 Intelligence (multi-trait analysis); LIHC cis rs2115630 0.691 rs8040066 chr15:85176465 G/C cg11189052 chr15:85197271 WDR73 -0.49 -7.6 -0.38 2.93e-13 P wave terminal force; LIHC cis rs6988985 0.560 rs2078674 chr8:143928233 G/T cg23373978 chr8:143916136 GML -0.29 -6.12 -0.31 2.56e-9 Plasma androstenedione levels in resected early stage-receptor positive breast cancer; LIHC cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg06481639 chr22:41940642 POLR3H -0.58 -6.05 -0.31 3.73e-9 Vitiligo; LIHC cis rs919433 0.783 rs787980 chr2:198239225 C/T cg10820045 chr2:198174542 NA 0.56 9.01 0.44 1.46e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs911119 1.000 rs6114209 chr20:23622266 G/C cg16589663 chr20:23618590 CST3 0.74 7.56 0.38 3.64e-13 Chronic kidney disease; LIHC cis rs600806 0.850 rs115935180 chr1:109976775 C/G cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.48 -0.37 6.42e-13 Intelligence (multi-trait analysis); LIHC cis rs72627509 0.523 rs12650282 chr4:57733604 A/G cg26694713 chr4:57773883 REST -0.42 -5.82 -0.3 1.35e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9916302 0.752 rs8071300 chr17:37508524 G/C cg07936489 chr17:37558343 FBXL20 0.85 12.19 0.55 1.26e-28 Glomerular filtration rate (creatinine); LIHC cis rs2932538 1.000 rs2932538 chr1:113216543 A/G cg22162597 chr1:113214053 CAPZA1 -0.72 -11.07 -0.51 1.49e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1691799 0.899 rs1168310 chr12:66726355 A/G cg16791601 chr12:66731901 HELB 0.53 12.44 0.56 1.46e-29 White blood cell count (basophil); LIHC cis rs2404602 0.662 rs908817 chr15:76639191 G/A cg23625390 chr15:77176239 SCAPER -0.46 -7.67 -0.38 1.86e-13 Blood metabolite levels; LIHC cis rs600806 0.888 rs444387 chr1:109851127 A/G cg16275483 chr1:110013120 SYPL2 -0.5 -6.13 -0.31 2.38e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg02290350 chr8:58132656 NA 0.48 9.39 0.45 8.97e-19 Developmental language disorder (linguistic errors); LIHC cis rs2274273 0.868 rs6573007 chr14:55625938 T/G cg04306507 chr14:55594613 LGALS3 0.32 6.17 0.32 1.94e-9 Protein biomarker; LIHC cis rs9790314 1.000 rs7653361 chr3:160992291 C/T cg03342759 chr3:160939853 NMD3 -0.74 -9.05 -0.44 1.1e-17 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg05564831 chr3:52568323 NT5DC2 0.37 6.04 0.31 3.93e-9 Bipolar disorder; LIHC trans rs2262909 0.962 rs11667209 chr19:22259467 A/G cg05197062 chr11:11642011 GALNTL4 0.42 6.08 0.31 3.17e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs861020 0.604 rs3766612 chr1:210020013 G/T cg05527609 chr1:210001259 C1orf107 -0.95 -14.87 -0.63 6.08e-39 Orofacial clefts; LIHC cis rs3812111 0.677 rs1204849 chr6:116525269 C/T cg08036074 chr6:116424633 NT5DC1 -0.39 -6.31 -0.32 8.7e-10 Age-related macular degeneration; LIHC cis rs6933660 0.536 rs3800274 chr6:151759192 T/G cg10883421 chr6:151773342 RMND1;C6orf211 0.43 6.12 0.31 2.51e-9 Menarche (age at onset); LIHC cis rs6912958 1.000 rs6454630 chr6:88171357 C/G cg08069147 chr6:88032118 GJB7;C6orf162 0.37 6.39 0.33 5.47e-10 Monocyte percentage of white cells; LIHC trans rs75804782 0.581 rs55931535 chr2:239372632 A/G cg01134436 chr17:81009848 B3GNTL1 0.86 7.2 0.36 3.75e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs943466 0.513 rs943467 chr6:33731811 A/T cg25922239 chr6:33757077 LEMD2 0.44 7.46 0.37 6.98e-13 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs8078723 0.933 rs4794822 chr17:38156712 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.22 -0.45 3.18e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2559856 1.000 rs2695296 chr12:102085487 T/C cg12924262 chr12:102091054 CHPT1 0.51 8.21 0.41 4.64e-15 Blood protein levels; LIHC cis rs7267979 1.000 rs2424700 chr20:25266513 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs763121 0.785 rs6001203 chr22:39099602 T/C cg21395723 chr22:39101663 GTPBP1 0.4 6.67 0.34 1.04e-10 Menopause (age at onset); LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.49 0.76 2.02e-65 Height; LIHC cis rs9443189 0.526 rs10943255 chr6:76225928 T/A cg01950844 chr6:76311363 SENP6 0.89 10.75 0.5 2.11e-23 Prostate cancer; LIHC cis rs4450131 0.898 rs3824804 chr10:126326606 C/T cg20435097 chr10:126320824 FAM53B 0.53 9.7 0.46 8.51e-20 White blood cell count (basophil); LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.72 12.3 0.55 4.83e-29 Prudent dietary pattern; LIHC cis rs1005277 0.522 rs200943 chr10:38148730 A/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.5 -0.46 3.79e-19 Extrinsic epigenetic age acceleration; LIHC cis rs10876993 0.890 rs115106209 chr12:58059331 G/A cg15848620 chr12:58087721 OS9 -0.54 -7.41 -0.37 9.97e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs4919087 0.561 rs34288920 chr10:99083483 C/T cg25902810 chr10:99078978 FRAT1 -0.59 -6.96 -0.35 1.75e-11 Monocyte count; LIHC trans rs3749237 1.000 rs11130214 chr3:49735746 C/G cg21659725 chr3:3221576 CRBN -0.78 -12.6 -0.56 3.76e-30 Resting heart rate; LIHC cis rs35306767 0.714 rs67696450 chr10:1090684 C/T cg26597838 chr10:835615 NA 0.77 7.44 0.37 7.95e-13 Eosinophil percentage of granulocytes; LIHC cis rs600806 0.745 rs12136063 chr1:110014170 A/G cg08911820 chr1:110026001 ATXN7L2 0.55 7.22 0.36 3.32e-12 Intelligence (multi-trait analysis); LIHC cis rs600806 0.888 rs3879449 chr1:109904971 A/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.896 rs809774 chr1:46560244 T/A cg06784218 chr1:46089804 CCDC17 -0.38 -7.0 -0.35 1.35e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13256369 0.950 rs13248096 chr8:8577476 C/T cg00074818 chr8:8560427 CLDN23 0.37 6.24 0.32 1.27e-9 Obesity-related traits; LIHC cis rs2228479 0.850 rs11645240 chr16:89837326 T/C cg19635926 chr16:89946313 TCF25 0.49 6.3 0.32 9.24e-10 Skin colour saturation; LIHC cis rs8062405 1.000 rs12325113 chr16:28848668 T/C cg00204512 chr16:28754710 NA 0.36 6.43 0.33 4.28e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10080237 0.564 rs2490230 chr6:80812464 G/A cg08355045 chr6:80787529 NA 0.35 7.1 0.36 7.45e-12 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals; LIHC cis rs7937682 0.737 rs663763 chr11:111422217 C/T cg09085632 chr11:111637200 PPP2R1B -0.75 -9.35 -0.45 1.18e-18 Primary sclerosing cholangitis; LIHC cis rs9611519 0.894 rs9611488 chr22:41462592 G/T cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.14e-14 Neuroticism; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg26338869 chr17:61819248 STRADA 0.61 8.91 0.43 3.16e-17 Prudent dietary pattern; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11897690 chr12:111051732 TCTN1 0.38 6.1 0.31 2.86e-9 Immature fraction of reticulocytes; LIHC cis rs986417 1.000 rs1950319 chr14:61048844 T/C cg27398547 chr14:60952738 C14orf39 0.71 7.69 0.38 1.61e-13 Gut microbiota (bacterial taxa); LIHC cis rs992157 0.767 rs2014615 chr2:219171191 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.76 12.2 0.55 1.15e-28 Colorectal cancer; LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg21747090 chr2:27597821 SNX17 -0.44 -6.68 -0.34 9.87e-11 Total body bone mineral density; LIHC cis rs8114671 0.804 rs6088666 chr20:33564570 A/G cg07148914 chr20:33460835 GGT7 0.6 9.22 0.45 3.01e-18 Height; LIHC cis rs7917772 0.636 rs2249845 chr10:104512095 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -6.1 -0.31 2.9e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 15.16 0.63 4.74e-40 Prudent dietary pattern; LIHC cis rs67311347 0.506 rs55962832 chr3:40244451 T/C cg00091569 chr3:40428383 ENTPD3 0.36 5.73 0.3 2.18e-8 Renal cell carcinoma; LIHC cis rs11792861 0.926 rs58795279 chr9:111851902 A/T cg13535736 chr9:111863775 C9orf5 -0.38 -5.73 -0.3 2.21e-8 Menarche (age at onset); LIHC cis rs916888 0.773 rs199443 chr17:44819565 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.72 6.92 0.35 2.18e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs3806843 0.898 rs3756335 chr5:140213510 A/T cg26395211 chr5:140044315 WDR55 -0.42 -6.11 -0.31 2.76e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10504073 0.647 rs11785310 chr8:50025035 G/A cg00325661 chr8:49890786 NA 0.33 7.37 0.37 1.27e-12 Blood metabolite ratios; LIHC cis rs9549367 0.577 rs3024713 chr13:113813321 G/A cg18105134 chr13:113819100 PROZ -0.77 -12.05 -0.55 4.03e-28 Platelet distribution width; LIHC cis rs7659604 0.539 rs7686084 chr4:122764725 A/C cg20573242 chr4:122745356 CCNA2 0.53 7.81 0.39 6.92e-14 Type 2 diabetes; LIHC cis rs2760061 0.626 rs672907 chr1:228120345 G/A cg02753203 chr1:228287806 NA -0.49 -7.87 -0.39 4.68e-14 Diastolic blood pressure; LIHC trans rs11098499 0.542 rs7677836 chr4:120310638 T/A cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs2439831 0.850 rs12442129 chr15:44055856 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.42 0.41 1.09e-15 Lung cancer in ever smokers; LIHC cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg06481639 chr22:41940642 POLR3H 0.6 5.77 0.3 1.81e-8 Cannabis dependence symptom count; LIHC cis rs6459788 0.585 rs6950818 chr7:157235364 C/G cg17306686 chr7:157230923 NA 0.39 8.51 0.42 5.73e-16 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs7131987 0.903 rs11050162 chr12:29420054 T/G cg21522988 chr12:29376872 FAR2 0.28 6.38 0.33 5.81e-10 QT interval; LIHC cis rs35110281 0.807 rs2838326 chr21:45014315 C/T cg01579765 chr21:45077557 HSF2BP -0.33 -6.63 -0.34 1.29e-10 Mean corpuscular volume; LIHC cis rs797680 0.927 rs1000607 chr1:93772001 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.97 -0.31 5.84e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs1003719 0.591 rs2018521 chr21:38517264 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.54 -6.84 -0.35 3.65e-11 Eye color traits; LIHC cis rs67460515 0.500 rs1345156 chr3:160649272 G/T cg03342759 chr3:160939853 NMD3 0.5 6.97 0.35 1.63e-11 Parkinson's disease; LIHC cis rs1008375 0.966 rs2872957 chr4:17651757 C/A cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs160652 chr7:65538431 A/G cg18252515 chr7:66147081 NA -1.21 -15.29 -0.64 1.45e-40 Diabetic kidney disease; LIHC cis rs4819052 0.851 rs4819049 chr21:46673086 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.82 0.39 6.79e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg05555928 chr11:63887634 MACROD1 0.55 7.41 0.37 1.03e-12 Mean platelet volume; LIHC cis rs2370759 1.000 rs16933177 chr10:32565705 G/A cg05361325 chr10:32636312 EPC1 -0.51 -6.24 -0.32 1.31e-9 Sexual dysfunction (female); LIHC cis rs8060686 0.545 rs12596883 chr16:68172416 A/T cg09835421 chr16:68378352 PRMT7 -0.54 -6.05 -0.31 3.78e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs7552404 1.000 rs4646961 chr1:76217169 G/A cg03433033 chr1:76189801 ACADM 0.65 9.18 0.44 4.29e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9918079 0.542 rs12499412 chr4:15602252 G/C cg21123203 chr4:15471301 CC2D2A 0.45 7.23 0.36 3.24e-12 Obesity-related traits; LIHC cis rs2370759 0.945 rs10508773 chr10:32575444 C/T cg18270830 chr10:32634957 EPC1 0.53 6.44 0.33 4.04e-10 Sexual dysfunction (female); LIHC cis rs2282802 0.685 rs13177186 chr5:139640476 A/G cg26211634 chr5:139558579 C5orf32 0.39 5.97 0.31 6.1e-9 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.731 rs10896350 chr11:68386373 A/C cg20283391 chr11:68216788 NA -0.39 -6.23 -0.32 1.34e-9 Total body bone mineral density; LIHC cis rs4853036 0.951 rs13393656 chr2:70119255 C/A cg02498382 chr2:70120550 SNRNP27 -0.43 -6.87 -0.35 2.95e-11 Colorectal or endometrial cancer; LIHC cis rs17401966 0.931 rs12130563 chr1:10428452 G/A cg15208524 chr1:10270712 KIF1B 0.41 6.16 0.32 2.03e-9 Hepatocellular carcinoma; LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs1003719 0.788 rs59637309 chr21:38475398 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs9910055 0.530 rs2269908 chr17:42294198 G/C cg19774624 chr17:42201019 HDAC5 -0.56 -7.86 -0.39 5.16e-14 Total body bone mineral density; LIHC cis rs7534824 0.543 rs6577221 chr1:101420406 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.62 7.33 0.37 1.66e-12 Refractive astigmatism; LIHC cis rs5769765 0.955 rs5769761 chr22:50263641 G/T cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg23758822 chr17:41437982 NA 0.94 17.94 0.7 3.44e-51 Menopause (age at onset); LIHC cis rs4700695 0.640 rs27083 chr5:65435865 C/T cg21114390 chr5:65439923 SFRS12 -0.59 -8.6 -0.42 2.84e-16 Facial morphology (factor 19); LIHC cis rs2439831 0.681 rs1095386 chr15:43609509 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.75 11.26 0.52 3.23e-25 Lung cancer in ever smokers; LIHC cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg12463550 chr7:65579703 CRCP 0.68 7.09 0.36 7.69e-12 Diabetic kidney disease; LIHC cis rs644799 0.542 rs10831418 chr11:95468828 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.56 7.06 0.36 9.53e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1801251 0.964 rs10933411 chr2:233706847 A/G cg25237894 chr2:233734115 C2orf82 -0.58 -11.39 -0.52 1.1e-25 Coronary artery disease; LIHC cis rs7223966 0.961 rs35844156 chr17:61837568 G/A cg05941027 chr17:61774174 LIMD2 0.38 7.88 0.39 4.54e-14 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7762018 1.000 rs6904601 chr6:170131905 T/G cg19338460 chr6:170058176 WDR27 -0.39 -5.98 -0.31 5.58e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs7777677 0.925 rs2156964 chr7:142372587 C/T cg21680980 chr1:221069572 NA -0.48 -6.08 -0.31 3.27e-9 Alcoholic chronic pancreatitis; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.21 -0.32 1.5e-9 Total body bone mineral density; LIHC cis rs77633900 0.614 rs2469242 chr15:76876710 A/G cg21673338 chr15:77095150 SCAPER -0.5 -7.24 -0.36 2.93e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs9486719 1.000 rs12213426 chr6:96896035 T/C cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs2976388 0.565 rs2572905 chr8:143797104 C/T cg06565975 chr8:143823917 SLURP1 0.33 6.16 0.32 2.07e-9 Urinary tract infection frequency; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00137585 chr16:3450828 ZNF174;ZNF434 -0.49 -6.37 -0.33 6.02e-10 Pancreatic cancer; LIHC cis rs7618501 0.521 rs7615206 chr3:49937505 T/C cg21467203 chr3:49911342 NA -0.59 -10.62 -0.5 5.81e-23 Intelligence (multi-trait analysis); LIHC cis rs929354 0.713 rs3802129 chr7:156965297 G/A cg17757837 chr7:157058334 UBE3C 0.73 11.94 0.54 1.05e-27 Body mass index; LIHC cis rs17125944 0.505 rs17125746 chr14:53236079 C/T cg13660082 chr14:53194042 PSMC6 -0.45 -7.5 -0.38 5.52e-13 Alzheimer's disease (late onset); LIHC cis rs12477438 0.520 rs11695751 chr2:99708247 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 24.89 0.8 9.36e-79 Chronic sinus infection; LIHC cis rs10876993 0.784 rs10083154 chr12:58020933 G/A cg18357645 chr12:58087776 OS9 -0.51 -8.03 -0.4 1.61e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs2777491 0.957 rs2015781 chr15:41648967 C/G cg18705301 chr15:41695430 NDUFAF1 -0.58 -8.96 -0.44 2.15e-17 Ulcerative colitis; LIHC cis rs17401966 0.558 rs6541090 chr1:10402842 A/G cg19773385 chr1:10388646 KIF1B -0.32 -5.73 -0.3 2.19e-8 Hepatocellular carcinoma; LIHC cis rs896854 0.967 rs896853 chr8:95960855 G/C cg23172400 chr8:95962367 TP53INP1 -0.44 -10.2 -0.48 1.67e-21 Type 2 diabetes; LIHC cis rs892961 0.965 rs2411111 chr17:75402540 A/T cg01320579 chr17:75405842 SEPT9 0.51 8.57 0.42 3.64e-16 Airflow obstruction; LIHC cis rs892961 0.899 rs66749226 chr17:75412826 G/A cg01320579 chr17:75405842 SEPT9 0.54 7.72 0.39 1.31e-13 Airflow obstruction; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg08556938 chr17:58512855 NA 0.41 6.43 0.33 4.21e-10 Immature fraction of reticulocytes; LIHC cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg00684032 chr4:1343700 KIAA1530 0.36 5.92 0.3 7.91e-9 Obesity-related traits; LIHC cis rs2204008 0.627 rs1851117 chr12:38398987 G/T cg26384229 chr12:38710491 ALG10B 0.6 8.29 0.41 2.71e-15 Bladder cancer; LIHC cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg18357526 chr6:26021779 HIST1H4A -0.6 -8.4 -0.41 1.24e-15 Blood metabolite levels; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg08219700 chr8:58056026 NA 0.51 6.89 0.35 2.73e-11 Developmental language disorder (linguistic errors); LIHC cis rs9807989 0.507 rs6543133 chr2:103040177 A/T cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma; LIHC cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.44 0.45 6.09e-19 Bipolar disorder; LIHC cis rs1005277 0.540 rs116205409 chr10:38478970 G/A cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.27 -0.32 1.06e-9 Extrinsic epigenetic age acceleration; LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg21747090 chr2:27597821 SNX17 -0.4 -5.82 -0.3 1.36e-8 Total body bone mineral density; LIHC trans rs6600671 0.934 rs67718113 chr1:121238910 C/T cg09829573 chr1:144692074 NBPF9 0.42 7.11 0.36 6.93e-12 Hip geometry; LIHC cis rs6783573 0.894 rs939408 chr3:46599079 C/A cg21489266 chr3:46619131 LRRC2;TDGF1 -0.4 -6.02 -0.31 4.38e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs11122272 0.735 rs2749704 chr1:231526243 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs7085104 0.632 rs4290163 chr10:104610926 G/T cg15744005 chr10:104629667 AS3MT -0.43 -9.64 -0.46 1.34e-19 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs4878497 0.646 rs10511906 chr9:32442492 A/G cg14296220 chr9:32431791 ACO1 0.6 10.43 0.49 2.59e-22 Inflammatory skin disease; LIHC cis rs1865721 0.848 rs12966327 chr18:73208445 C/T cg26385618 chr18:73139727 C18orf62 -0.29 -7.3 -0.37 1.99e-12 Intelligence; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg21248554 chr2:27665150 KRTCAP3 -0.44 -6.12 -0.31 2.63e-9 Total body bone mineral density; LIHC cis rs2439831 0.867 rs935901 chr15:43651256 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.79 8.63 0.42 2.42e-16 Lung cancer in ever smokers; LIHC cis rs4908768 0.539 rs1809332 chr1:8656434 C/T cg20416874 chr1:8611966 RERE -0.62 -11.27 -0.52 2.9e-25 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7843479 0.509 rs3758156 chr8:21770796 A/G cg17168535 chr8:21777572 XPO7 0.52 9.36 0.45 1.05e-18 Mean corpuscular volume; LIHC cis rs7927771 0.542 rs11039336 chr11:47706141 A/G cg20307385 chr11:47447363 PSMC3 -0.71 -10.68 -0.5 3.68e-23 Subjective well-being; LIHC cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg26939375 chr7:64535504 NA 0.47 7.19 0.36 4.13e-12 Calcium levels; LIHC cis rs12477438 0.520 rs13023744 chr2:99738224 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs4555082 0.874 rs28625632 chr14:105748849 G/T cg10792982 chr14:105748885 BRF1 0.45 6.06 0.31 3.66e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9457247 1.000 rs398278 chr6:167388169 A/G cg23791538 chr6:167370224 RNASET2 -0.59 -9.35 -0.45 1.15e-18 Crohn's disease; LIHC trans rs11088226 1.000 rs2833889 chr21:33927768 G/T cg09050820 chr6:167586206 TCP10L2 -0.73 -11.35 -0.52 1.52e-25 Gastritis; LIHC cis rs11628318 0.614 rs7143048 chr14:103119800 C/T cg01864069 chr14:103024347 NA 0.45 7.03 0.36 1.13e-11 Platelet count; LIHC cis rs2404602 0.618 rs12442266 chr15:76567142 T/C cg22467129 chr15:76604101 ETFA -0.38 -6.34 -0.32 7.16e-10 Blood metabolite levels; LIHC cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg18357526 chr6:26021779 HIST1H4A 0.6 8.53 0.42 4.77e-16 Blood metabolite levels; LIHC cis rs763121 0.819 rs138700 chr22:39129999 A/G cg06022373 chr22:39101656 GTPBP1 0.7 13.6 0.59 5.91e-34 Menopause (age at onset); LIHC trans rs208520 0.690 rs207096 chr6:66797287 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.13 -0.44 5.97e-18 Exhaled nitric oxide output; LIHC trans rs4843747 0.671 rs28465438 chr16:88103714 G/A cg09572067 chr16:29127029 RRN3P2 0.53 8.55 0.42 4.2e-16 Menopause (age at onset); LIHC cis rs1494373 0.722 rs6659246 chr1:220931227 A/C cg06786860 chr1:220876396 NA 0.38 5.82 0.3 1.32e-8 Response to antipsychotic therapy (extrapyramidal side effects); LIHC cis rs1577917 0.538 rs7755996 chr6:86423720 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.42 0.33 4.62e-10 Response to antipsychotic treatment; LIHC cis rs6785206 0.772 rs2811493 chr3:128357299 C/G cg16766828 chr3:128327626 NA -0.63 -6.98 -0.35 1.52e-11 Lymphocyte percentage of white cells; LIHC cis rs1816752 0.905 rs9581026 chr13:24997926 C/A cg22771759 chr13:24902376 NA 0.32 6.59 0.34 1.71e-10 Obesity-related traits; LIHC cis rs2153535 0.580 rs9406161 chr6:8466144 G/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs16828019 0.777 rs16911 chr1:41498021 C/T cg03387723 chr1:41708464 SCMH1 -0.41 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs9733 0.596 rs6692960 chr1:150695965 G/A cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs7923452 0.507 rs103441 chr10:30778184 C/T cg25182066 chr10:30743637 MAP3K8 -0.69 -11.21 -0.52 4.68e-25 Itch intensity from mosquito bite; LIHC cis rs6964587 0.967 rs10231350 chr7:91808499 G/T cg17063962 chr7:91808500 NA 1.06 22.31 0.77 1.12e-68 Breast cancer; LIHC trans rs10411161 0.810 rs59911578 chr19:52385597 G/C cg22319618 chr22:45562946 NUP50 -0.59 -7.05 -0.36 9.8e-12 Breast cancer; LIHC cis rs769267 0.825 rs1469713 chr19:19528806 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.8 0.3 1.54e-8 Tonsillectomy; LIHC cis rs9399135 0.935 rs4445070 chr6:135309212 C/T cg24558204 chr6:135376177 HBS1L 0.39 6.39 0.33 5.57e-10 Red blood cell count; LIHC cis rs10508774 0.810 rs12252927 chr10:32726139 G/T cg01819863 chr10:32635814 EPC1 0.61 5.88 0.3 9.61e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8078723 0.866 rs7502514 chr17:38188844 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.53 8.55 0.42 4.12e-16 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs7714584 0.590 rs115823027 chr5:150265951 G/A cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs67478160 0.572 rs8016014 chr14:104293798 G/C cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.06 -0.36 9.1e-12 Schizophrenia; LIHC cis rs9926296 0.593 rs6500456 chr16:89888341 T/C cg27121462 chr16:89883253 FANCA 0.46 7.18 0.36 4.39e-12 Vitiligo; LIHC cis rs7772486 0.754 rs9390358 chr6:146145678 C/T cg23711669 chr6:146136114 FBXO30 0.66 11.87 0.54 1.9e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs898097 0.756 rs11655103 chr17:80813467 T/C cg15369054 chr17:80825471 TBCD 0.42 6.03 0.31 4.31e-9 Breast cancer; LIHC cis rs11628318 0.614 rs11847932 chr14:103185435 T/G cg01864069 chr14:103024347 NA 0.47 7.18 0.36 4.29e-12 Platelet count; LIHC cis rs28374715 0.662 rs521890 chr15:41473143 C/T cg18705301 chr15:41695430 NDUFAF1 -0.83 -9.69 -0.46 9.18e-20 Ulcerative colitis; LIHC cis rs7772486 0.686 rs2328708 chr6:146095739 G/A cg23711669 chr6:146136114 FBXO30 -0.62 -11.07 -0.51 1.45e-24 Lobe attachment (rater-scored or self-reported); LIHC trans rs2018683 0.932 rs4386882 chr7:28989270 C/T cg19402173 chr7:128379420 CALU -0.41 -6.3 -0.32 8.91e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.7 10.06 0.48 5.15e-21 Lymphocyte counts; LIHC cis rs362296 0.597 rs3129320 chr4:3265130 G/C cg06533319 chr4:3265114 C4orf44 0.38 7.5 0.38 5.55e-13 Parental longevity (mother's age at death); LIHC cis rs7917772 0.503 rs11191320 chr10:104293394 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6669384 0.737 rs882198 chr1:208036509 A/G cg22525895 chr1:207977042 MIR29B2 0.51 6.08 0.31 3.15e-9 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs9790314 0.846 rs7652267 chr3:160998497 A/G cg03342759 chr3:160939853 NMD3 -0.81 -13.34 -0.59 5.67e-33 Morning vs. evening chronotype; LIHC trans rs983392 0.680 rs11230201 chr11:59996994 C/G cg17275991 chr19:58003312 ZNF419 0.43 6.19 0.32 1.7e-9 Alzheimer's disease (late onset); LIHC cis rs2933343 0.700 rs1680779 chr3:128614770 G/A cg25356066 chr3:128598488 ACAD9 0.56 7.56 0.38 3.76e-13 IgG glycosylation; LIHC cis rs734999 1.000 rs10797432 chr1:2501338 C/T cg18854424 chr1:2615690 NA 0.3 6.6 0.34 1.58e-10 Ulcerative colitis; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg02290350 chr8:58132656 NA 0.51 11.04 0.51 1.9e-24 Developmental language disorder (linguistic errors); LIHC cis rs8027181 0.958 rs4776614 chr15:73082468 C/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 7.76 0.39 9.83e-14 Triglyceride levels; LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.64 -9.46 -0.46 4.96e-19 Lymphocyte counts; LIHC cis rs875971 0.830 rs778711 chr7:65851657 G/A cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC cis rs6435862 0.517 rs6757091 chr2:215672793 G/C cg04530015 chr2:215796436 ABCA12 0.49 9.01 0.44 1.46e-17 Neuroblastoma (high-risk); LIHC cis rs748404 0.660 rs2467742 chr15:43750237 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.35 0.37 1.44e-12 Lung cancer; LIHC cis rs2279817 0.863 rs871089 chr1:18017704 C/T cg21791023 chr1:18019539 ARHGEF10L 0.68 8.05 0.4 1.36e-14 Neuroticism; LIHC cis rs7927592 0.956 rs12365160 chr11:68250419 A/G cg16797656 chr11:68205561 LRP5 0.54 8.67 0.42 1.78e-16 Total body bone mineral density; LIHC cis rs1639906 0.895 rs62443039 chr7:2209354 C/T cg04267008 chr7:1944627 MAD1L1 0.43 5.77 0.3 1.81e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs875971 0.638 rs35986979 chr7:66088990 G/A cg18876405 chr7:65276391 NA -0.45 -7.93 -0.39 3.07e-14 Aortic root size; LIHC cis rs10504073 0.669 rs62507253 chr8:50028836 C/T cg00325661 chr8:49890786 NA 0.33 7.35 0.37 1.48e-12 Blood metabolite ratios; LIHC cis rs4906332 1.000 rs8004780 chr14:103853360 A/C cg19000871 chr14:103996768 TRMT61A -0.4 -6.86 -0.35 3.3e-11 Coronary artery disease; LIHC cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg03806693 chr22:41940476 POLR3H 1.02 11.8 0.54 3.5e-27 Vitiligo; LIHC cis rs9300255 0.537 rs10772993 chr12:123644714 A/G cg00376283 chr12:123451042 ABCB9 0.65 7.04 0.36 1.06e-11 Neutrophil percentage of white cells; LIHC cis rs8060686 0.641 rs59708959 chr16:68123916 A/T cg05110241 chr16:68378359 PRMT7 -0.6 -6.86 -0.35 3.29e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs2120019 1.000 rs7175720 chr15:75348962 C/G cg17294928 chr15:75287854 SCAMP5 0.52 8.02 0.4 1.66e-14 Blood trace element (Zn levels); LIHC cis rs2070488 1.000 rs4147024 chr3:38456664 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.66 0.65 4.59e-42 Electrocardiographic conduction measures; LIHC cis rs12594515 1.000 rs11070464 chr15:45984776 C/A cg19682013 chr15:45996608 NA 0.4 7.09 0.36 7.7e-12 Waist circumference;Weight; LIHC cis rs11690935 0.921 rs7355523 chr2:172744421 T/C cg13550731 chr2:172543902 DYNC1I2 -0.89 -16.66 -0.67 4.74e-46 Schizophrenia; LIHC cis rs10540 1.000 rs12786555 chr11:506229 C/T cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.71e-15 Body mass index; LIHC cis rs6089584 0.566 rs2181589 chr20:60622817 C/T cg23262073 chr20:60523788 NA 0.28 5.91 0.3 8.22e-9 Body mass index; LIHC cis rs2574704 1.000 rs2574704 chr3:11655381 T/C cg15876825 chr3:11651881 VGLL4 0.5 8.2 0.41 4.88e-15 Body mass index; LIHC cis rs2797160 1.000 rs2797160 chr6:126010116 A/G cg05901451 chr6:126070800 HEY2 0.45 7.45 0.37 7.66e-13 Endometrial cancer; LIHC trans rs1814175 0.538 rs1684260 chr11:49224231 G/A cg03929089 chr4:120376271 NA 0.78 13.71 0.6 2.06e-34 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06586915 chr7:65958596 NA 0.44 6.25 0.32 1.24e-9 Pancreatic cancer; LIHC cis rs13223928 0.565 rs10951053 chr7:3155579 C/T cg19214707 chr7:3157722 NA -0.43 -8.23 -0.41 3.9e-15 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs6089829 0.962 rs3899032 chr20:61658542 G/A cg03213289 chr20:61660250 NA 0.51 9.06 0.44 1.04e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs4906332 1.000 rs7155980 chr14:103922419 C/G cg04998671 chr14:104000505 TRMT61A -0.46 -6.3 -0.32 9.31e-10 Coronary artery disease; LIHC cis rs9303280 0.806 rs12936409 chr17:38043649 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.85 0.3 1.15e-8 Self-reported allergy; LIHC cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg00484396 chr16:3507460 NAT15 -0.44 -8.61 -0.42 2.79e-16 Tuberculosis; LIHC cis rs9790314 1.000 rs6794601 chr3:160946769 C/T cg04691961 chr3:161091175 C3orf57 -0.33 -5.73 -0.3 2.23e-8 Morning vs. evening chronotype; LIHC cis rs1055129 0.560 rs2305913 chr17:73922941 T/C cg10935138 chr17:73851978 WBP2 0.48 7.09 0.36 7.83e-12 White matter hyperintensity burden; LIHC cis rs7119 0.717 rs11636412 chr15:77767291 C/T cg17802220 chr15:77601643 NA -0.4 -6.9 -0.35 2.52e-11 Type 2 diabetes; LIHC cis rs7193541 0.684 rs4888262 chr16:74670458 C/T cg01733217 chr16:74700730 RFWD3 0.92 22.57 0.77 1.05e-69 Multiple myeloma; LIHC cis rs4819052 0.851 rs13047104 chr21:46673562 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.88 0.39 4.48e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7927592 0.956 rs12271290 chr11:68326236 A/G cg16797656 chr11:68205561 LRP5 -0.5 -8.03 -0.4 1.56e-14 Total body bone mineral density; LIHC cis rs858239 0.600 rs9691762 chr7:23125922 G/C cg23682824 chr7:23144976 KLHL7 0.44 6.64 0.34 1.26e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs11627756 0.957 rs7144340 chr14:103128777 G/T cg12046867 chr14:103022105 NA 0.39 5.87 0.3 1.02e-8 Mean platelet volume; LIHC cis rs7772486 0.597 rs2485631 chr6:146190077 G/C cg23711669 chr6:146136114 FBXO30 0.62 9.49 0.46 3.93e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs9911578 0.967 rs8082544 chr17:57185807 C/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.94 -0.7 3.35e-51 Intelligence (multi-trait analysis); LIHC cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg02359409 chr6:42947317 PEX6 -0.48 -6.79 -0.34 4.99e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs78456975 0.506 rs6756310 chr2:1549809 A/G cg01028140 chr2:1542097 TPO -0.45 -7.16 -0.36 4.98e-12 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2197308 0.565 rs12809769 chr12:37909968 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs7249142 0.562 rs2239370 chr19:19292674 T/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.45 -7.55 -0.38 3.94e-13 IgG glycosylation; LIHC cis rs9399135 0.967 rs6925424 chr6:135313948 T/A cg24558204 chr6:135376177 HBS1L 0.4 6.65 0.34 1.15e-10 Red blood cell count; LIHC cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg10360323 chr17:41437877 NA 0.39 5.71 0.3 2.44e-8 Menopause (age at onset); LIHC trans rs1624005 0.933 rs1667657 chr14:43398628 T/C cg11960719 chr5:1510684 LPCAT1 -0.36 -6.26 -0.32 1.16e-9 Methotrexate-induced interstitial lung disease in rheumatoid arthritis; LIHC cis rs970821 1.000 rs17258588 chr8:124746618 C/T cg00283535 chr8:124749564 ANXA13 0.35 5.91 0.3 8.29e-9 Breast cancer; LIHC cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg12310025 chr6:25882481 NA -0.68 -8.92 -0.43 2.88e-17 Intelligence (multi-trait analysis); LIHC cis rs11098699 0.821 rs4833890 chr4:124217864 G/C cg09941581 chr4:124220074 SPATA5 0.33 6.72 0.34 7.55e-11 Mosquito bite size; LIHC cis rs11583043 0.918 rs58029001 chr1:101393409 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.3 0.32 8.96e-10 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1046896 0.503 rs12947062 chr17:80686370 A/G cg02711726 chr17:80685570 FN3KRP 0.58 11.69 0.53 8.52e-27 Glycated hemoglobin levels; LIHC cis rs6545883 0.899 rs1562309 chr2:61770126 C/A cg15711740 chr2:61764176 XPO1 -0.43 -6.08 -0.31 3.18e-9 Tuberculosis; LIHC trans rs9929218 0.861 rs4783667 chr16:68752878 C/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -9.17 -0.44 4.46e-18 Colorectal cancer; LIHC cis rs9902453 0.868 rs8066731 chr17:28523121 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.61 9.55 0.46 2.51e-19 Coffee consumption (cups per day); LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC trans rs17154702 0.506 rs2427 chr8:8641125 A/G cg06710121 chr8:12235606 FAM66A -0.52 -6.09 -0.31 3.04e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC trans rs11722228 0.549 rs56146302 chr4:10081052 C/T cg26043149 chr18:55253948 FECH 0.96 14.01 0.6 1.46e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs55882075 0.808 rs6867806 chr5:179179585 C/G cg14593053 chr5:179126677 CANX 0.41 7.33 0.37 1.69e-12 Monocyte percentage of white cells; LIHC cis rs459571 1.000 rs2810489 chr9:136922700 C/T cg13789015 chr9:136890014 NCRNA00094 0.4 7.36 0.37 1.39e-12 Platelet distribution width; LIHC cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg06640241 chr16:89574553 SPG7 0.85 15.64 0.65 5.69e-42 Multiple myeloma (IgH translocation); LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.47 0.62 2.37e-37 Prudent dietary pattern; LIHC cis rs1005277 0.579 rs2474572 chr10:38385316 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.39 -5.77 -0.3 1.81e-8 Extrinsic epigenetic age acceleration; LIHC trans rs7209395 0.700 rs17690171 chr17:64202857 C/T cg27381822 chr6:149304457 UST -0.32 -6.08 -0.31 3.17e-9 &beta2-Glycoprotein I (β2-GPI) plasma levels;Weight; LIHC cis rs769267 0.931 rs2965197 chr19:19470910 C/T cg03709012 chr19:19516395 GATAD2A -0.93 -15.77 -0.65 1.66e-42 Tonsillectomy; LIHC cis rs17253792 0.915 rs17832389 chr14:56185836 A/G cg01858014 chr14:56050164 KTN1 -0.78 -7.77 -0.39 8.98e-14 Putamen volume; LIHC cis rs903552 1.000 rs12907048 chr15:102003873 G/T cg25677261 chr15:102009856 PCSK6 -0.44 -6.0 -0.31 5.1e-9 Diabetic kidney disease; LIHC cis rs7264396 0.563 rs6058302 chr20:34290037 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.5 -0.42 6.02e-16 Total cholesterol levels; LIHC cis rs13108904 0.517 rs4974551 chr4:1336410 C/A cg05665937 chr4:1216051 CTBP1 0.44 5.83 0.3 1.29e-8 Obesity-related traits; LIHC cis rs950169 0.887 rs220333 chr15:85091133 C/T cg12863693 chr15:85201151 NMB 0.44 6.09 0.31 3.03e-9 Schizophrenia; LIHC cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg13047869 chr3:10149882 C3orf24 0.54 6.41 0.33 4.82e-10 Alzheimer's disease; LIHC cis rs2303759 0.709 rs2278405 chr19:49812403 A/C cg22590775 chr19:49891494 CCDC155 -0.46 -7.22 -0.36 3.3e-12 Multiple sclerosis; LIHC cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.63 0.53 1.49e-26 Alzheimer's disease; LIHC cis rs2243480 1.000 rs709607 chr7:65449541 C/G cg18252515 chr7:66147081 NA 1.13 13.45 0.59 2.2e-33 Diabetic kidney disease; LIHC cis rs3736485 0.966 rs7182977 chr15:51854130 C/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg01788221 chr16:89496183 ANKRD11 -0.38 -5.85 -0.3 1.14e-8 Multiple myeloma (IgH translocation); LIHC cis rs8062405 1.000 rs62037367 chr16:28874547 C/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12497850 0.931 rs13316620 chr3:49045355 T/C cg06212747 chr3:49208901 KLHDC8B 0.6 7.7 0.38 1.49e-13 Parkinson's disease; LIHC cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg00149659 chr3:10157352 C3orf10 0.63 6.86 0.35 3.27e-11 Alzheimer's disease; LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.71 0.76 2.62e-66 Height; LIHC cis rs6582630 0.599 rs1851114 chr12:38424671 C/T cg26384229 chr12:38710491 ALG10B -0.45 -5.88 -0.3 1e-8 Drug-induced liver injury (flucloxacillin); LIHC trans rs116095464 0.558 rs6869925 chr5:264036 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC trans rs208520 1.000 rs72884033 chr6:66995747 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.67 7.2 0.36 3.84e-12 Exhaled nitric oxide output; LIHC cis rs2235642 0.582 rs2072990 chr16:1567651 A/G cg09065629 chr16:1709722 CRAMP1L 0.34 5.88 0.3 9.66e-9 Coronary artery disease; LIHC trans rs875971 0.660 rs3857686 chr7:66036191 C/T cg26939375 chr7:64535504 NA -0.43 -6.94 -0.35 2.02e-11 Aortic root size; LIHC cis rs2540917 0.728 rs11125841 chr2:60627565 A/G cg00543073 chr2:60773386 BCL11A -0.34 -6.7 -0.34 8.8e-11 Mean corpuscular volume; LIHC cis rs739401 0.595 rs2073843 chr11:2970855 A/G cg25174290 chr11:3078921 CARS 0.58 8.7 0.43 1.38e-16 Longevity; LIHC cis rs8072100 0.512 rs9303533 chr17:45386540 A/G cg08085267 chr17:45401833 C17orf57 -0.6 -8.77 -0.43 8.67e-17 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs12824058 0.831 rs7310433 chr12:130809289 C/T cg24229701 chr12:130821962 PIWIL1 0.44 6.78 0.34 5.4e-11 Menopause (age at onset); LIHC cis rs9322817 0.691 rs4591886 chr6:105249970 G/C cg02098413 chr6:105308735 HACE1 -0.41 -7.68 -0.38 1.68e-13 Thyroid stimulating hormone; LIHC cis rs2153535 0.580 rs6926759 chr6:8456176 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.78 0.43 8.18e-17 Motion sickness; LIHC cis rs1982963 0.585 rs77091361 chr14:52486961 C/T cg10843707 chr14:52510701 NID2 0.39 6.08 0.31 3.3e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs3820068 0.581 rs16851851 chr1:15929628 C/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs7635838 0.892 rs34830847 chr3:11437798 A/C cg00170343 chr3:11313890 ATG7 0.45 7.02 0.35 1.23e-11 HDL cholesterol; LIHC cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg27572855 chr1:25598939 RHD 0.4 8.64 0.42 2.23e-16 Plateletcrit;Mean corpuscular volume; LIHC trans rs2460905 0.867 rs2466273 chr8:12866004 A/C cg05956521 chr1:157668115 FCRL3 -0.44 -6.45 -0.33 3.74e-10 Post-traumatic stress disorder; LIHC cis rs9381040 0.655 rs2294695 chr6:41036770 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -6.07 -0.31 3.38e-9 Alzheimer's disease (late onset); LIHC cis rs4555082 0.874 rs2245329 chr14:105719181 T/C cg13114125 chr14:105738426 BRF1 -0.69 -9.08 -0.44 8.83e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg12016809 chr21:47604291 C21orf56 -0.47 -7.32 -0.37 1.75e-12 Testicular germ cell tumor; LIHC cis rs7617773 0.815 rs7624450 chr3:48350375 A/G cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs8017423 0.967 rs2277515 chr14:90723000 A/G cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.18e-41 Mortality in heart failure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08749122 chr1:150459996 TARS2 0.42 6.21 0.32 1.5e-9 Pancreatic cancer; LIHC cis rs1395 0.744 rs11126932 chr2:27476282 G/A cg22903471 chr2:27725779 GCKR -0.4 -6.0 -0.31 4.95e-9 Blood metabolite levels; LIHC cis rs10216189 1.000 rs7799665 chr7:5527501 G/A cg05318486 chr7:5553423 FBXL18 -0.56 -8.12 -0.4 8.47e-15 Relative hand skill in reading disability; LIHC cis rs72781680 0.752 rs72796130 chr2:23919740 T/C cg08917208 chr2:24149416 ATAD2B 0.97 8.16 0.4 6.38e-15 Lymphocyte counts; LIHC cis rs3815700 1.000 rs3815700 chr19:33093252 T/C cg02997394 chr19:33096574 ANKRD27 0.72 9.25 0.45 2.55e-18 Eosinophilic esophagitis; LIHC cis rs9486715 1.000 rs11153085 chr6:97066355 A/T cg18709589 chr6:96969512 KIAA0776 -0.35 -6.05 -0.31 3.81e-9 Headache; LIHC cis rs9611565 0.649 rs6002480 chr22:42176917 A/T cg03806693 chr22:41940476 POLR3H -0.82 -8.92 -0.43 2.86e-17 Vitiligo; LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg14004847 chr7:1930337 MAD1L1 -0.47 -6.9 -0.35 2.49e-11 Bipolar disorder and schizophrenia; LIHC cis rs6598955 0.670 rs7520517 chr1:26556385 A/C cg04990556 chr1:26633338 UBXN11 -0.57 -9.35 -0.45 1.17e-18 Obesity-related traits; LIHC cis rs7727544 0.684 rs274561 chr5:131719228 A/C cg24060327 chr5:131705240 SLC22A5 -0.6 -8.61 -0.42 2.77e-16 Blood metabolite levels; LIHC cis rs796364 0.806 rs11674293 chr2:201026743 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.66 -0.34 1.13e-10 Schizophrenia; LIHC cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg17554472 chr22:41940697 POLR3H 0.56 6.01 0.31 4.84e-9 Vitiligo; LIHC cis rs12791968 1.000 rs1005935 chr11:45002498 A/C cg11846598 chr11:44996168 LOC221122 -0.45 -7.98 -0.4 2.28e-14 Inhibitory control; LIHC cis rs6061231 0.793 rs6061512 chr20:60976929 G/A cg24112000 chr20:60950667 NA -0.62 -8.2 -0.41 5.05e-15 Colorectal cancer; LIHC cis rs7772486 0.790 rs9390365 chr6:146235626 A/G cg13319975 chr6:146136371 FBXO30 0.38 6.04 0.31 4.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg25364880 chr3:44379878 C3orf23 0.45 6.33 0.32 7.77e-10 Depressive symptoms; LIHC cis rs4638749 0.677 rs6713634 chr2:108827907 T/G cg25838818 chr2:108905173 SULT1C2 -0.4 -7.0 -0.35 1.37e-11 Blood pressure; LIHC cis rs274567 0.501 rs272856 chr5:131687081 G/C cg24060327 chr5:131705240 SLC22A5 -0.78 -12.1 -0.55 2.58e-28 Blood metabolite levels; LIHC cis rs12928939 0.774 rs7192860 chr16:71643622 G/A cg03805757 chr16:71968109 PKD1L3 -0.51 -5.86 -0.3 1.07e-8 Post bronchodilator FEV1; LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.42 -0.41 1.04e-15 Lymphocyte counts; LIHC cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg10802521 chr3:52805072 NEK4 -0.42 -7.02 -0.35 1.23e-11 Bipolar disorder; LIHC cis rs3762637 1.000 rs9882100 chr3:122169908 T/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC trans rs75804782 0.641 rs72987309 chr2:239348025 A/G cg01134436 chr17:81009848 B3GNTL1 0.83 7.3 0.37 2.04e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs6988636 1.000 rs13260626 chr8:124190317 C/T cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs2625529 0.824 rs4131630 chr15:72355398 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.92 -0.3 7.89e-9 Red blood cell count; LIHC cis rs921968 0.643 rs833083 chr2:219336959 A/T cg18887096 chr2:219472410 PLCD4 -0.38 -6.7 -0.34 8.8e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs12765878 1.000 rs2902639 chr10:105658588 G/C cg11005552 chr10:105648138 OBFC1 0.38 6.08 0.31 3.26e-9 Coronary artery disease; LIHC cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg03034668 chr16:1723424 CRAMP1L -0.39 -6.76 -0.34 6.01e-11 Coronary artery disease; LIHC cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.73 -0.3 2.25e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7131987 0.903 rs67517901 chr12:29421346 A/G cg05697976 chr12:29376483 FAR2 0.32 6.44 0.33 4.12e-10 QT interval; LIHC cis rs208520 0.802 rs208499 chr6:66932146 C/T cg07460842 chr6:66804631 NA -0.76 -8.39 -0.41 1.34e-15 Exhaled nitric oxide output; LIHC cis rs34779708 0.966 rs34776628 chr10:35426324 G/A cg04310649 chr10:35416472 CREM -0.43 -5.86 -0.3 1.11e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9326248 0.501 rs4938351 chr11:117022352 A/C cg01368799 chr11:117014884 PAFAH1B2 0.68 10.56 0.5 9.22e-23 Blood protein levels; LIHC cis rs16828019 0.852 rs11209531 chr1:41571021 C/T cg03962019 chr1:41807865 NA 0.5 7.36 0.37 1.35e-12 Intelligence (multi-trait analysis); LIHC cis rs10876993 0.928 rs2169988 chr12:58071165 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.05 -0.31 3.75e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs9910055 0.530 rs11656758 chr17:42301541 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.42 7.32 0.37 1.81e-12 Total body bone mineral density; LIHC cis rs7116495 0.541 rs579320 chr11:71794954 G/T cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs2880765 0.545 rs11631739 chr15:86012578 T/C cg10818794 chr15:86012489 AKAP13 -0.43 -6.5 -0.33 2.77e-10 Coronary artery disease; LIHC cis rs769267 0.965 rs10419245 chr19:19383755 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.43 5.9 0.3 8.88e-9 Tonsillectomy; LIHC cis rs4474465 0.850 rs7127028 chr11:78262324 A/G cg27205649 chr11:78285834 NARS2 0.44 6.77 0.34 5.56e-11 Alzheimer's disease (survival time); LIHC cis rs9899728 0.572 rs9915968 chr17:73059616 G/C cg27626185 chr17:73056755 KCTD2 -0.66 -11.83 -0.54 2.78e-27 Alzheimer's disease or small vessel stroke; LIHC cis rs9902453 0.904 rs4994353 chr17:28386280 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.82 -0.54 2.95e-27 Coffee consumption (cups per day); LIHC cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg12386194 chr3:101231763 SENP7 0.47 7.03 0.36 1.1e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs8177253 0.965 rs3811658 chr3:133476852 C/T cg12373951 chr3:133503437 NA 0.69 12.56 0.56 5.2e-30 Iron status biomarkers; LIHC cis rs757110 0.590 rs7484027 chr11:17368381 T/A cg15432903 chr11:17409602 KCNJ11 -0.56 -8.57 -0.42 3.66e-16 Type 2 diabetes; LIHC cis rs2576037 0.583 rs2164104 chr18:44567743 G/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.71 -10.95 -0.51 3.91e-24 Personality dimensions; LIHC cis rs727505 1.000 rs67585224 chr7:124537476 A/C cg23710748 chr7:124431027 NA -0.32 -5.71 -0.3 2.44e-8 Lewy body disease; LIHC cis rs7617773 0.963 rs6766754 chr3:48182589 T/C cg11946769 chr3:48343235 NME6 -0.57 -7.63 -0.38 2.28e-13 Coronary artery disease; LIHC cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg11764359 chr7:65958608 NA -0.56 -5.87 -0.3 1.03e-8 Diabetic kidney disease; LIHC cis rs12971120 0.891 rs11151960 chr18:72177232 G/A cg25817165 chr18:72167213 CNDP2 -0.71 -12.33 -0.55 3.73e-29 Refractive error; LIHC cis rs35306767 0.855 rs61830900 chr10:871481 C/G cg26597838 chr10:835615 NA 1.5 16.55 0.67 1.29e-45 Eosinophil percentage of granulocytes; LIHC cis rs477692 0.629 rs945231 chr10:131294827 A/G cg19680672 chr10:131412579 MGMT -0.39 -5.9 -0.3 8.73e-9 Response to temozolomide; LIHC cis rs916888 0.697 rs199516 chr17:44856485 C/T cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs28830936 1.000 rs28754734 chr15:42093152 C/T cg17847044 chr15:42102381 MAPKBP1 -0.33 -6.59 -0.34 1.64e-10 Diastolic blood pressure; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg11905131 chr22:24372483 LOC391322 -0.67 -9.84 -0.47 2.83e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12594515 1.000 rs8043291 chr15:45996247 T/A cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs644799 1.000 rs11021319 chr11:95523123 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.86 0.47 2.37e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg03464473 chr7:72343742 NA -0.3 -6.06 -0.31 3.53e-9 Migraine with aura; LIHC cis rs1355223 0.752 rs286893 chr11:34674882 C/G cg11058730 chr11:34937778 PDHX;APIP 0.47 6.47 0.33 3.44e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg08499158 chr17:42289980 UBTF -0.52 -8.55 -0.42 4.12e-16 Total body bone mineral density; LIHC cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg23758822 chr17:41437982 NA 0.94 17.49 0.69 2.15e-49 Menopause (age at onset); LIHC cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg12751644 chr20:60527061 NA -0.54 -9.1 -0.44 7.46e-18 Obesity-related traits; LIHC cis rs3736485 0.966 rs12102203 chr15:51791559 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.15 -0.32 2.18e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7044106 0.762 rs1547267 chr9:123408736 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.25 0.52 3.29e-25 Hip circumference adjusted for BMI; LIHC cis rs765787 0.530 rs2554453 chr15:45522107 A/G cg24006582 chr15:45444508 DUOX1 -0.5 -7.26 -0.37 2.56e-12 Uric acid levels; LIHC cis rs807669 0.903 rs1780642 chr22:19170604 T/C cg02655711 chr22:19163373 SLC25A1 0.74 11.47 0.53 5.53e-26 Metabolite levels; LIHC cis rs11122272 0.735 rs11122280 chr1:231519816 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.25 -0.48 1.15e-21 Hemoglobin concentration; LIHC cis rs11676348 0.818 rs7425447 chr2:218980183 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.1 -0.31 2.94e-9 Ulcerative colitis; LIHC cis rs10779751 0.770 rs11121696 chr1:11238063 A/G cg08854313 chr1:11322531 MTOR -0.63 -8.12 -0.4 8.65e-15 Body mass index; LIHC cis rs7412746 0.658 rs6657388 chr1:150748786 A/G cg17724175 chr1:150552817 MCL1 0.48 9.3 0.45 1.65e-18 Melanoma; LIHC cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg18252515 chr7:66147081 NA 1.29 17.4 0.69 4.95e-49 Diabetic kidney disease; LIHC cis rs1801251 0.778 rs2675967 chr2:233736133 C/G cg08000102 chr2:233561755 GIGYF2 -0.7 -9.91 -0.47 1.59e-20 Coronary artery disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19143760 chr3:148709578 GYG1 0.43 6.06 0.31 3.67e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1005277 0.541 rs2472177 chr10:38384015 T/G cg27523141 chr10:43048294 ZNF37B 0.37 6.4 0.33 5.12e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9399135 0.967 rs9376077 chr6:135299713 C/G cg24558204 chr6:135376177 HBS1L 0.39 6.37 0.33 5.98e-10 Red blood cell count; LIHC cis rs7582720 1.000 rs72926767 chr2:203796814 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9918079 0.506 rs7696127 chr4:15642953 T/A cg24225360 chr4:15471699 CC2D2A -0.39 -6.23 -0.32 1.4e-9 Obesity-related traits; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg04727924 chr7:799746 HEATR2 0.41 6.36 0.33 6.53e-10 Perceived unattractiveness to mosquitoes; LIHC cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg15691649 chr6:25882328 NA 0.51 7.34 0.37 1.58e-12 Blood metabolite levels; LIHC cis rs4906332 0.811 rs2296487 chr14:103996205 T/C cg19000871 chr14:103996768 TRMT61A -0.55 -9.08 -0.44 9.02e-18 Coronary artery disease; LIHC cis rs34779708 0.801 rs34592588 chr10:35540134 A/G cg03585969 chr10:35415529 CREM 0.78 11.45 0.53 6.52e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs16958440 1.000 rs62096474 chr18:44647504 G/A cg17192377 chr18:44677553 HDHD2 0.6 6.74 0.34 6.88e-11 Sitting height ratio; LIHC cis rs1538970 0.924 rs1494812 chr1:45876999 C/T cg24296786 chr1:45957014 TESK2 -0.5 -7.3 -0.37 2.09e-12 Platelet count; LIHC cis rs17685 0.753 rs10476 chr7:75696420 C/T cg04610667 chr7:75704037 NA 0.34 6.15 0.32 2.2e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1046896 1.000 rs9909940 chr17:80689036 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.46 7.06 0.36 9.44e-12 Glycated hemoglobin levels; LIHC trans rs11098499 0.955 rs35434465 chr4:120169378 C/G cg25214090 chr10:38739885 LOC399744 0.51 7.72 0.39 1.27e-13 Corneal astigmatism; LIHC cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg26939375 chr7:64535504 NA 0.48 7.29 0.37 2.1e-12 Aortic root size; LIHC cis rs13161895 0.938 rs594202 chr5:179417335 C/T cg06664874 chr5:179499304 RNF130 0.57 7.02 0.35 1.21e-11 LDL cholesterol; LIHC cis rs9916302 0.861 rs593480 chr17:37453780 A/C cg00129232 chr17:37814104 STARD3 0.38 6.08 0.31 3.15e-9 Glomerular filtration rate (creatinine); LIHC cis rs35306767 0.953 rs1106064 chr10:957211 G/A cg20503657 chr10:835505 NA 0.9 10.77 0.5 1.76e-23 Eosinophil percentage of granulocytes; LIHC cis rs10792665 0.934 rs11233383 chr11:82659498 T/C cg24227371 chr11:82718527 RAB30 -0.29 -6.81 -0.35 4.53e-11 Obesity-related traits; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg06873352 chr17:61820015 STRADA 0.69 11.62 0.53 1.57e-26 Prudent dietary pattern; LIHC cis rs634534 0.563 rs470192 chr11:65724291 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.38 5.77 0.3 1.78e-8 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs1865760 0.820 rs9348697 chr6:25890834 C/T cg17691542 chr6:26056736 HIST1H1C 0.39 5.85 0.3 1.18e-8 Height; LIHC cis rs240764 0.853 rs12191199 chr6:101008093 C/T cg09795085 chr6:101329169 ASCC3 -0.49 -6.65 -0.34 1.14e-10 Neuroticism; LIHC cis rs10791097 0.690 rs12284540 chr11:130729772 T/C cg09137382 chr11:130731461 NA 0.41 6.16 0.32 2.07e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2834188 1.000 rs2843994 chr21:34706870 G/A cg04842828 chr21:34696676 IFNAR1 0.48 6.26 0.32 1.14e-9 Narcolepsy; LIHC cis rs2290405 0.527 rs4690329 chr4:931385 T/A cg04824913 chr4:887549 GAK 0.53 8.03 0.4 1.63e-14 Systemic sclerosis; LIHC cis rs2153535 0.580 rs7741456 chr6:8452424 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC cis rs8016982 0.963 rs2099108 chr14:81675420 C/G cg01989461 chr14:81687754 GTF2A1 0.56 11.06 0.51 1.65e-24 Schizophrenia; LIHC cis rs2806561 1.000 rs2473851 chr1:23489869 A/G cg19743168 chr1:23544995 NA 0.4 7.37 0.37 1.32e-12 Height; LIHC cis rs66573146 1.000 rs55672215 chr4:6970529 T/C cg15105060 chr4:7024189 TBC1D14 -0.85 -6.71 -0.34 7.95e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs11122272 0.735 rs910823 chr1:231498766 G/T cg06096015 chr1:231504339 EGLN1 0.51 9.46 0.46 5.03e-19 Hemoglobin concentration; LIHC cis rs72843506 1.000 rs7223910 chr17:19982768 G/A cg13482628 chr17:19912719 NA 0.48 6.29 0.32 9.74e-10 Schizophrenia; LIHC cis rs12291225 0.877 rs2303974 chr11:14264979 G/T cg19336497 chr11:14380999 RRAS2 -0.55 -10.31 -0.49 7.25e-22 Sense of smell; LIHC cis rs1707322 0.752 rs11211173 chr1:46219376 C/T cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs763121 0.651 rs738249 chr22:39037979 T/C cg06022373 chr22:39101656 GTPBP1 0.69 11.97 0.54 8.45e-28 Menopause (age at onset); LIHC trans rs1728785 1.000 rs1749791 chr16:68572347 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.82e-9 Ulcerative colitis; LIHC cis rs2073300 1.000 rs6132622 chr20:23442240 A/T cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22867288 chr6:57086716 RAB23 0.49 6.84 0.35 3.62e-11 Lung function (FEV1/FVC); LIHC cis rs798554 0.757 rs1183085 chr7:2875570 G/A cg13628971 chr7:2884303 GNA12 0.52 7.25 0.36 2.84e-12 Height; LIHC cis rs6912958 0.712 rs7746465 chr6:88348996 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.91 -0.39 3.48e-14 Monocyte percentage of white cells; LIHC cis rs1008375 1.000 rs1974624 chr4:17650281 A/G cg02297831 chr4:17616191 MED28 0.49 7.59 0.38 3.11e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7264396 0.563 rs2425130 chr20:34335059 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.75 -0.43 1.02e-16 Total cholesterol levels; LIHC trans rs2739330 0.791 rs9612520 chr22:24269459 G/T cg06437703 chr8:37914619 EIF4EBP1 -0.59 -8.99 -0.44 1.73e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6089584 0.924 rs6142906 chr20:60552554 G/C cg23262073 chr20:60523788 NA -0.28 -5.76 -0.3 1.89e-8 Body mass index; LIHC cis rs1866706 0.896 rs1866711 chr11:12875301 C/T cg25843174 chr11:12811716 TEAD1 -0.29 -6.08 -0.31 3.13e-9 Intelligence (multi-trait analysis); LIHC cis rs9942416 0.660 rs67054144 chr5:74991443 G/A cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs6960043 0.560 rs7811965 chr7:15041076 A/T cg19272540 chr7:15055459 NA 0.24 6.56 0.33 2.02e-10 Type 2 diabetes; LIHC cis rs66573146 0.539 rs56659624 chr4:7069377 G/C cg19539972 chr4:7069911 GRPEL1 -0.7 -7.62 -0.38 2.54e-13 Granulocyte percentage of myeloid white cells; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01744729 chr13:113474194 ATP11A 0.42 6.05 0.31 3.79e-9 Longevity; LIHC cis rs1005277 0.579 rs1740749 chr10:38521646 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg11905131 chr22:24372483 LOC391322 -0.73 -11.08 -0.51 1.42e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7165170 0.549 rs10775250 chr15:91099156 T/C cg26821196 chr15:91095069 CRTC3 0.39 7.09 0.36 7.92e-12 Crohn's disease;Inflammatory bowel disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13559217 chr19:5119331 KDM4B -0.4 -6.21 -0.32 1.55e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1499614 1.000 rs60326618 chr7:66166358 G/A cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs2066819 1.000 rs77032009 chr12:56679971 A/G cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs644799 0.582 rs473157 chr11:95596874 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.55 7.81 0.39 7.29e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -5.9 -0.3 8.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6967414 0.786 rs3757482 chr7:6748927 A/G cg00387323 chr7:6746715 ZNF12 0.64 7.01 0.35 1.28e-11 Hematocrit;Hemoglobin concentration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08655493 chr21:33765248 URB1;C21orf119 0.4 6.25 0.32 1.2e-9 Cognitive function; LIHC cis rs7131987 0.650 rs4331146 chr12:29440083 G/T cg16970926 chr12:29381810 FAR2 0.28 5.91 0.3 8.13e-9 QT interval; LIHC cis rs6570726 0.846 rs9376954 chr6:145943737 T/A cg23711669 chr6:146136114 FBXO30 0.64 11.5 0.53 4.37e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.967 rs17411375 chr3:47395135 C/T cg16586182 chr3:47516702 SCAP 0.58 10.71 0.5 2.8e-23 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15188491 chr1:146644106 PRKAB2 0.39 6.06 0.31 3.65e-9 Cognitive function; LIHC cis rs1801251 0.656 rs10211596 chr2:233699415 C/T cg25237894 chr2:233734115 C2orf82 -0.38 -7.34 -0.37 1.57e-12 Coronary artery disease; LIHC cis rs6466055 0.720 rs13239067 chr7:105011629 T/A cg04380332 chr7:105027541 SRPK2 -0.37 -6.9 -0.35 2.52e-11 Schizophrenia; LIHC cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.79 0.5 1.49e-23 Platelet count; LIHC cis rs950169 0.922 rs4842939 chr15:84827966 C/T cg17507749 chr15:85114479 UBE2QP1 -0.63 -7.33 -0.37 1.65e-12 Schizophrenia; LIHC cis rs7224737 0.956 rs8081900 chr17:40289875 G/A cg00647820 chr17:40259828 DHX58 -0.28 -5.91 -0.3 8.45e-9 Fibrinogen levels; LIHC cis rs7772486 0.790 rs6926076 chr6:146232804 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -5.94 -0.31 6.91e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2795502 0.873 rs2077626 chr10:43410962 A/G cg27426351 chr10:43362370 NA 0.47 5.75 0.3 1.95e-8 Blood protein levels; LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg24209194 chr3:40518798 ZNF619 0.61 9.09 0.44 8.13e-18 Renal cell carcinoma; LIHC cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg13395646 chr4:1353034 KIAA1530 -0.65 -8.95 -0.44 2.34e-17 Obesity-related traits; LIHC cis rs9457247 0.935 rs1794697 chr6:167395410 C/T cg23791538 chr6:167370224 RNASET2 -0.68 -11.75 -0.54 5.28e-27 Crohn's disease; LIHC cis rs6435862 0.593 rs34732883 chr2:215674371 C/T cg04004882 chr2:215674386 BARD1 -0.59 -9.01 -0.44 1.47e-17 Neuroblastoma (high-risk); LIHC cis rs2842992 0.830 rs2758320 chr6:160070676 T/G cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.13 0.4 7.9e-15 Age-related macular degeneration (geographic atrophy); LIHC cis rs8017423 0.586 rs2896134 chr14:90831293 G/A cg04374321 chr14:90722782 PSMC1 -0.52 -7.6 -0.38 2.93e-13 Mortality in heart failure; LIHC cis rs9911578 1.000 rs302848 chr17:56686454 C/T cg05425664 chr17:57184151 TRIM37 -0.56 -8.48 -0.42 6.81e-16 Intelligence (multi-trait analysis); LIHC cis rs79387448 0.638 rs11465698 chr2:103054577 T/C cg09003973 chr2:102972529 NA 1.11 9.33 0.45 1.38e-18 Gut microbiota (bacterial taxa); LIHC cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg06238570 chr21:40685208 BRWD1 -0.53 -9.0 -0.44 1.62e-17 Cognitive function; LIHC cis rs9393692 0.905 rs9366649 chr6:26329103 A/T cg00631329 chr6:26305371 NA 0.43 7.51 0.38 5.15e-13 Educational attainment; LIHC cis rs13064411 0.696 rs6438161 chr3:113227637 G/A cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC trans rs17685 0.712 rs56965035 chr7:75795670 G/A cg19862616 chr7:65841803 NCRNA00174 0.94 19.23 0.72 2.29e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs311392 0.966 rs404354 chr8:55087196 A/G cg20636351 chr8:55087400 NA -0.4 -8.06 -0.4 1.31e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs2839186 0.721 rs3788252 chr21:47661235 C/T cg09417038 chr21:47716443 C21orf57 -0.46 -6.88 -0.35 2.9100000000000002e-11 Testicular germ cell tumor; LIHC cis rs9457247 0.582 rs9459855 chr6:167466150 G/T cg07741184 chr6:167504864 NA 0.36 8.32 0.41 2.16e-15 Crohn's disease; LIHC cis rs875971 0.830 rs778711 chr7:65851657 G/A cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs11583043 1.000 rs6700743 chr1:101447384 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 8.3 0.41 2.45e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs60843830 0.964 rs7584915 chr2:264227 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.67 9.69 0.46 9.01e-20 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs6542838 0.641 rs13005124 chr2:99527680 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.75 -0.34 6.48e-11 Fear of minor pain; LIHC cis rs9790314 0.502 rs34972965 chr3:160984296 G/A cg03342759 chr3:160939853 NMD3 -0.67 -10.11 -0.48 3.36e-21 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs743757 1.000 rs2298955 chr3:50431194 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.46 -7.02 -0.35 1.22e-11 Diastolic blood pressure; LIHC cis rs7193541 0.585 rs3851729 chr16:74485529 A/G cg01733217 chr16:74700730 RFWD3 -0.67 -12.99 -0.57 1.28e-31 Multiple myeloma; LIHC cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg10360323 chr17:41437877 NA 0.41 6.06 0.31 3.58e-9 Menopause (age at onset); LIHC trans rs9940464 0.901 rs12597147 chr16:83367049 G/A cg13016115 chr14:23388406 RBM23 0.39 6.26 0.32 1.18e-9 Malaria; LIHC cis rs9457247 1.000 rs2769354 chr6:167379771 G/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.85 -0.47 2.62e-20 Crohn's disease; LIHC cis rs916888 0.697 rs199516 chr17:44856485 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2242116 1.000 rs1138518 chr3:46944274 T/C cg02527881 chr3:46936655 PTH1R -0.5 -10.22 -0.48 1.47e-21 Birth weight; LIHC cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg06497051 chr1:156261200 TMEM79 -0.36 -5.73 -0.3 2.21e-8 Tonsillectomy; LIHC cis rs6089829 0.962 rs6062778 chr20:61663959 A/G cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs10791097 0.694 rs10160281 chr11:130742788 T/C cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs796364 1.000 rs11694369 chr2:200741720 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -5.74 -0.3 2.07e-8 Schizophrenia; LIHC cis rs600806 1.000 rs600806 chr1:109840629 A/G cg08911820 chr1:110026001 ATXN7L2 0.5 6.01 0.31 4.66e-9 Intelligence (multi-trait analysis); LIHC cis rs2302190 0.769 rs7218778 chr17:56664248 T/G cg12560992 chr17:57184187 TRIM37 0.69 8.91 0.43 3.17e-17 Vitamin D levels; LIHC cis rs7927771 1.000 rs4752857 chr11:47655752 C/T cg20307385 chr11:47447363 PSMC3 -0.45 -5.88 -0.3 9.64e-9 Subjective well-being; LIHC cis rs11098499 0.863 rs3822190 chr4:120428098 G/A cg09307838 chr4:120376055 NA 0.76 11.62 0.53 1.52e-26 Corneal astigmatism; LIHC trans rs11146838 1 rs11146838 chr10:39149977 A/T cg23533926 chr12:111358616 MYL2 -0.35 -6.51 -0.33 2.63e-10 Breast cancer; LIHC cis rs6089584 0.889 rs6142923 chr20:60596617 C/T cg23262073 chr20:60523788 NA 0.3 5.96 0.31 6.4e-9 Body mass index; LIHC cis rs3924048 0.574 rs11121928 chr1:12615888 C/G cg00291366 chr1:12616550 NA 0.42 8.83 0.43 5.6e-17 Optic cup area; LIHC cis rs7107174 1.000 rs2373009 chr11:77945815 T/A cg02023728 chr11:77925099 USP35 0.5 9.29 0.45 1.84e-18 Testicular germ cell tumor; LIHC cis rs8077889 0.672 rs1230397 chr17:41844689 A/G cg26893861 chr17:41843967 DUSP3 1.16 21.94 0.76 3.11e-67 Triglycerides; LIHC cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg15691649 chr6:25882328 NA -0.54 -7.08 -0.36 8.5e-12 Intelligence (multi-trait analysis); LIHC cis rs3008870 1.000 rs3008894 chr1:67377739 A/G cg02640540 chr1:67518911 SLC35D1 0.43 5.88 0.3 9.82e-9 Lymphocyte percentage of white cells; LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg22903471 chr2:27725779 GCKR -0.49 -8.48 -0.42 6.86e-16 Total body bone mineral density; LIHC cis rs1401999 1.000 rs9858774 chr3:183652736 G/A cg01324343 chr3:183735012 ABCC5 0.74 12.14 0.55 1.93e-28 Anterior chamber depth; LIHC cis rs611744 0.967 rs584555 chr8:109218612 C/G cg21045802 chr8:109455806 TTC35 0.52 8.87 0.43 4.22e-17 Dupuytren's disease; LIHC cis rs8067545 0.750 rs7223305 chr17:19990986 A/G cg13482628 chr17:19912719 NA 0.52 8.83 0.43 5.45e-17 Schizophrenia; LIHC cis rs769267 0.929 rs2905431 chr19:19482882 G/A cg03709012 chr19:19516395 GATAD2A -1.01 -18.1 -0.7 7.56e-52 Tonsillectomy; LIHC cis rs1005277 0.579 rs2505194 chr10:38393881 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.68 -0.5 3.57e-23 Extrinsic epigenetic age acceleration; LIHC cis rs10504073 0.584 rs56078938 chr8:49940342 A/C cg00325661 chr8:49890786 NA 0.36 7.95 0.39 2.74e-14 Blood metabolite ratios; LIHC cis rs10791097 0.694 rs4456262 chr11:130755813 C/T cg22079354 chr11:130786696 SNX19 -0.46 -6.33 -0.32 7.77e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11630290 0.649 rs1036910 chr15:64157015 T/C cg12036633 chr15:63758958 NA 0.62 6.6 0.34 1.59e-10 Iris characteristics; LIHC cis rs2412488 0.893 rs35978987 chr4:54358819 A/G cg22241045 chr4:54363911 LNX1 0.46 7.66 0.38 1.93e-13 DNA methylation (variation); LIHC cis rs17854409 0.764 rs8114722 chr20:61478492 G/A cg06598544 chr20:61472147 COL9A3 -0.84 -7.24 -0.36 3.07e-12 Obesity-related traits; LIHC cis rs5758511 0.514 rs5751222 chr22:42517922 T/A cg00645731 chr22:42541494 CYP2D7P1 0.52 8.34 0.41 1.84e-15 Birth weight; LIHC cis rs7903847 0.620 rs3737194 chr10:99130127 A/G cg08345082 chr10:99160200 RRP12 -0.35 -6.01 -0.31 4.78e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs12701220 0.655 rs10215292 chr7:1135263 A/G cg04498913 chr7:1135747 C7orf50 0.44 7.04 0.36 1.03e-11 Bronchopulmonary dysplasia; LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg02475777 chr4:1388615 CRIPAK 0.55 8.1 0.4 9.84e-15 Longevity; LIHC cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg16414030 chr3:133502952 NA -0.38 -5.74 -0.3 2.06e-8 Iron status biomarkers; LIHC cis rs1707322 0.752 rs28507722 chr1:46206540 A/G cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs881375 1.000 rs10117059 chr9:123653477 G/C cg14580859 chr9:123691850 NA 0.38 6.58 0.34 1.79e-10 Rheumatoid arthritis; LIHC cis rs7715806 0.500 rs17649248 chr5:74998426 C/T cg19683494 chr5:74908142 NA 0.69 7.79 0.39 7.91e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs757110 0.866 rs5213 chr11:17408404 C/T cg15432903 chr11:17409602 KCNJ11 0.68 10.84 0.51 1.01e-23 Type 2 diabetes; LIHC cis rs66573146 0.831 rs67665838 chr4:7064870 G/A cg06697600 chr4:7070879 GRPEL1 0.74 8.91 0.43 3.01e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs6831352 0.918 rs13129488 chr4:100053025 G/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs8017423 0.904 rs11623741 chr14:90804474 C/T cg14092571 chr14:90743983 NA -0.41 -6.52 -0.33 2.49e-10 Mortality in heart failure; LIHC cis rs1538970 0.924 rs1494812 chr1:45876999 C/T cg05343316 chr1:45956843 TESK2 0.59 8.54 0.42 4.33e-16 Platelet count; LIHC cis rs875971 1.000 rs6460292 chr7:65810075 G/A cg18252515 chr7:66147081 NA 0.42 6.03 0.31 4.37e-9 Aortic root size; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00166836 chr6:149721425 MAP3K7IP2;SUMO4 0.41 6.05 0.31 3.78e-9 Longevity; LIHC cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg11890956 chr21:40555474 PSMG1 0.97 13.01 0.58 1.05e-31 Cognitive function; LIHC cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg06212747 chr3:49208901 KLHDC8B 0.62 8.38 0.41 1.39e-15 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg06634786 chr22:41940651 POLR3H 0.72 7.46 0.37 7.03e-13 Vitiligo; LIHC cis rs2072499 0.966 rs1060604 chr1:156184268 T/C cg24450063 chr1:156163899 SLC25A44 1.05 17.2 0.68 3.19e-48 Testicular germ cell tumor; LIHC cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg17747265 chr1:1875780 NA -0.59 -11.12 -0.52 9.71e-25 Body mass index; LIHC cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.59 -0.56 4.11e-30 Alzheimer's disease; LIHC cis rs7904368 0.754 rs12269366 chr10:16850344 G/A cg14835575 chr10:16859367 RSU1 0.65 8.77 0.43 8.35e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs12824058 0.831 rs12322456 chr12:130813594 A/G cg24838063 chr12:130822603 PIWIL1 0.67 9.89 0.47 1.86e-20 Menopause (age at onset); LIHC cis rs4728302 0.869 rs10224575 chr7:133590875 G/A cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs11167764 0.945 rs13161849 chr5:141473395 A/G cg23435118 chr5:141488016 NDFIP1 -0.43 -5.77 -0.3 1.8e-8 Crohn's disease; LIHC cis rs7100689 0.784 rs7082705 chr10:82170856 C/T cg01528321 chr10:82214614 TSPAN14 -0.91 -13.45 -0.59 2.22e-33 Post bronchodilator FEV1; LIHC cis rs9916302 0.904 rs588193 chr17:37440439 A/C cg00129232 chr17:37814104 STARD3 0.39 6.23 0.32 1.34e-9 Glomerular filtration rate (creatinine); LIHC cis rs2439831 0.850 rs61390361 chr15:44159842 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.6 7.31 0.37 1.95e-12 Lung cancer in ever smokers; LIHC cis rs853679 0.517 rs2275508 chr6:28094731 T/C cg23485639 chr6:28045615 ZNF165 0.45 6.03 0.31 4.28e-9 Depression; LIHC cis rs992157 0.710 rs7569907 chr2:219070551 C/T cg00012203 chr2:219082015 ARPC2 0.92 16.59 0.67 9.39e-46 Colorectal cancer; LIHC trans rs747782 0.582 rs7949865 chr11:48346202 A/C cg15704280 chr7:45808275 SEPT13 -0.58 -6.1 -0.31 2.9e-9 Intraocular pressure; LIHC cis rs7503168 0.908 rs9907772 chr17:34000628 G/A cg05299278 chr17:33885742 SLFN14 -0.25 -5.77 -0.3 1.82e-8 Plateletcrit; LIHC cis rs804280 0.525 rs1004712 chr8:11622293 C/T cg12395012 chr8:11607386 GATA4 -0.45 -6.93 -0.35 2.08e-11 Myopia (pathological); LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg14709524 chr16:89940631 TCF25 0.51 6.82 0.35 4.18e-11 Skin colour saturation; LIHC cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg18252515 chr7:66147081 NA -1.26 -16.8 -0.67 1.31e-46 Diabetic kidney disease; LIHC cis rs7635838 0.785 rs2606735 chr3:11400714 A/C cg00170343 chr3:11313890 ATG7 0.49 7.79 0.39 8e-14 HDL cholesterol; LIHC cis rs2290416 0.892 rs59742520 chr8:144676234 G/C cg26536354 chr8:144654954 C8orf73 0.56 6.23 0.32 1.35e-9 Attention deficit hyperactivity disorder; LIHC cis rs16958440 0.867 rs16948928 chr18:44675821 C/T cg17192377 chr18:44677553 HDHD2 0.56 6.46 0.33 3.6e-10 Sitting height ratio; LIHC cis rs1816752 0.870 rs2033954 chr13:25010567 C/T cg02811702 chr13:24901961 NA 0.25 6.33 0.32 7.79e-10 Obesity-related traits; LIHC cis rs3784262 1.000 rs10851631 chr15:58242193 C/T cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.09 -0.31 2.97e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs4803468 0.967 rs284661 chr19:41932120 C/T cg09537434 chr19:41945824 ATP5SL -1.03 -21.09 -0.75 7.8e-64 Height; LIHC cis rs10463316 0.817 rs6880228 chr5:150778145 A/T cg03212797 chr5:150827313 SLC36A1 0.42 6.32 0.32 8.13e-10 Metabolite levels (Pyroglutamine); LIHC cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg24531977 chr5:56204891 C5orf35 -0.68 -9.88 -0.47 1.99e-20 Initial pursuit acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg19497325 chr3:43121668 C3orf39 0.42 6.09 0.31 3e-9 Longevity; LIHC cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg11764359 chr7:65958608 NA -0.58 -6.04 -0.31 4e-9 Diabetic kidney disease; LIHC cis rs6964587 0.773 rs38793 chr7:92027187 A/G cg17063962 chr7:91808500 NA -0.97 -16.23 -0.66 2.63e-44 Breast cancer; LIHC cis rs2404602 0.583 rs12438741 chr15:76542114 C/A cg22467129 chr15:76604101 ETFA -0.39 -6.49 -0.33 3.08e-10 Blood metabolite levels; LIHC cis rs933688 1.000 rs12654787 chr5:90713259 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.7 0.73 2.92e-58 Smoking behavior; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27654529 chr19:35418345 ZNF30 0.41 6.91 0.35 2.37e-11 Cognitive function; LIHC cis rs77637988 0.604 rs6722246 chr2:48597045 T/G cg15846641 chr2:48541264 FOXN2 0.58 7.77 0.39 9.18e-14 Joint mobility (Beighton score); LIHC cis rs8062405 0.964 rs7187333 chr16:28865916 G/A cg00204512 chr16:28754710 NA 0.36 6.43 0.33 4.28e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs34779708 0.897 rs12830 chr10:35302705 C/T cg03585969 chr10:35415529 CREM 0.87 13.18 0.58 2.4e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg13126279 chr21:47581558 C21orf56 -0.47 -7.7 -0.38 1.43e-13 Testicular germ cell tumor; LIHC trans rs66887589 0.720 rs2036858 chr4:120249237 A/C cg25214090 chr10:38739885 LOC399744 0.44 7.38 0.37 1.18e-12 Diastolic blood pressure; LIHC cis rs7903847 0.642 rs11189183 chr10:99144321 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9660992 0.789 rs1768584 chr1:205240145 A/G cg21545522 chr1:205238299 TMCC2 0.3 6.29 0.32 9.6e-10 Mean corpuscular volume;Mean platelet volume; LIHC cis rs6964587 0.610 rs6942852 chr7:91437883 A/C cg17063962 chr7:91808500 NA 0.6 9.77 0.47 4.71e-20 Breast cancer; LIHC cis rs9790314 0.779 rs12493960 chr3:160899772 T/C cg03342759 chr3:160939853 NMD3 -0.75 -9.24 -0.45 2.7e-18 Morning vs. evening chronotype; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg20349687 chr2:88927127 EIF2AK3 -0.4 -6.3 -0.32 9.23e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7959452 0.562 rs10878975 chr12:69782044 G/C cg14784868 chr12:69753453 YEATS4 0.94 20.44 0.74 3.16e-61 Blood protein levels; LIHC cis rs10744422 1.000 rs897386 chr12:123341289 A/C cg18912006 chr12:123335444 HIP1R -0.6 -7.29 -0.37 2.18e-12 Schizophrenia; LIHC trans rs2727020 0.681 rs2866362 chr11:49379316 A/G cg03929089 chr4:120376271 NA -0.84 -15.19 -0.63 3.57e-40 Coronary artery disease; LIHC cis rs611744 0.934 rs682954 chr8:109210559 C/T cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs12995491 0.569 rs6724281 chr2:88529531 T/G cg04169830 chr2:88471460 THNSL2 0.42 5.71 0.3 2.4e-8 Response to metformin (IC50); LIHC cis rs7208859 0.725 rs7210904 chr17:29170205 G/A cg14067834 chr17:29058358 SUZ12P 0.62 6.38 0.33 5.64e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg06481639 chr22:41940642 POLR3H 0.7 6.89 0.35 2.65e-11 Vitiligo; LIHC cis rs61542988 0.532 rs12673996 chr7:22833400 C/T cg11367502 chr7:22862612 TOMM7 0.54 8.68 0.42 1.67e-16 Fibrinogen levels; LIHC cis rs28374715 0.662 rs28382348 chr15:41487934 G/C cg18705301 chr15:41695430 NDUFAF1 -0.88 -9.72 -0.47 7.19e-20 Ulcerative colitis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13272430 chr14:67708475 MPP5 -0.49 -7.34 -0.37 1.58e-12 Cognitive function; LIHC cis rs919433 0.679 rs6737060 chr2:198524885 G/C cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs853679 0.542 rs34131763 chr6:28075000 A/C cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.49 0.38 6.02e-13 Electroencephalogram traits; LIHC cis rs67311347 1.000 rs6599094 chr3:40399593 A/G cg09455208 chr3:40491958 NA 0.33 6.5 0.33 2.83e-10 Renal cell carcinoma; LIHC cis rs2455799 0.613 rs6802048 chr3:15883933 A/G cg12698662 chr3:15914712 MIR563 -0.38 -7.09 -0.36 7.59e-12 Mean platelet volume; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs72653721 0.689 rs17697071 chr6:11052580 C/T cg13562911 chr6:11044106 ELOVL2 0.52 7.41 0.37 1.03e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs6504950 0.720 rs9895901 chr17:52984885 A/G cg10237252 chr17:52977213 TOM1L1 -0.38 -6.64 -0.34 1.23e-10 Breast cancer; LIHC cis rs6952808 0.965 rs11768541 chr7:1894884 G/A cg02951883 chr7:2050386 MAD1L1 -0.55 -8.0 -0.4 1.89e-14 Bipolar disorder and schizophrenia; LIHC cis rs7107174 1.000 rs2510050 chr11:77982564 A/G cg02023728 chr11:77925099 USP35 0.5 9.49 0.46 4.13e-19 Testicular germ cell tumor; LIHC cis rs5769707 0.632 rs135872 chr22:50009300 T/C cg01652190 chr22:50026171 C22orf34 -0.34 -7.61 -0.38 2.65e-13 Monocyte count;Monocyte percentage of white cells; LIHC trans rs1422110 0.515 rs1155791 chr5:85417582 A/C cg01787110 chr1:109008453 NBPF6 0.29 6.5 0.33 2.81e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs986417 0.748 rs4400969 chr14:61013298 A/C cg27398547 chr14:60952738 C14orf39 0.74 8.02 0.4 1.71e-14 Gut microbiota (bacterial taxa); LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg08469215 chr1:156261351 TMEM79 0.4 6.62 0.34 1.39e-10 Tonsillectomy; LIHC cis rs61990749 0.597 rs2267759 chr14:78147615 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.3 -0.49 7.3e-22 Fibroblast growth factor basic levels; LIHC cis rs244731 0.959 rs7721671 chr5:176630984 A/G cg17509989 chr5:176798049 RGS14 -0.66 -6.42 -0.33 4.57e-10 Urate levels in lean individuals; LIHC cis rs45430 1.000 rs443099 chr21:42743327 G/T cg06102954 chr21:42741788 MX2 0.36 6.27 0.32 1.07e-9 Melanoma; LIHC cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg05025164 chr4:1340916 KIAA1530 0.43 6.62 0.34 1.38e-10 Obesity-related traits; LIHC cis rs2361718 0.568 rs1042397 chr17:78092063 G/A cg09238746 chr17:78121135 EIF4A3 -0.51 -7.23 -0.36 3.22e-12 Yeast infection; LIHC cis rs2997447 0.761 rs61776620 chr1:26457980 T/C cg19633962 chr1:26362018 EXTL1 -0.67 -6.07 -0.31 3.37e-9 QRS complex (12-leadsum); LIHC cis rs7909074 1.000 rs10751360 chr10:45396971 G/A cg04218760 chr10:45406644 TMEM72 -0.23 -7.26 -0.37 2.67e-12 Mean corpuscular volume; LIHC trans rs4927850 1.000 rs7614767 chr3:195753451 C/T cg16724585 chr3:197361211 NA -0.47 -6.62 -0.34 1.4e-10 Pancreatic cancer; LIHC cis rs1797081 1.000 rs1797081 chr10:16874565 A/G cg23933602 chr10:16859644 RSU1 0.98 18.66 0.71 4.27e-54 Platelet distribution width; LIHC trans rs9388451 0.839 rs10457469 chr6:126083658 G/A cg05039488 chr6:79577232 IRAK1BP1 -0.56 -9.11 -0.44 7.25e-18 Brugada syndrome; LIHC cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg03452623 chr4:187889614 NA -0.33 -8.46 -0.42 7.86e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs67460515 0.926 rs66508859 chr3:160946351 C/T cg03342759 chr3:160939853 NMD3 -0.66 -9.89 -0.47 1.92e-20 Parkinson's disease; LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.89 -0.3 9.32e-9 Menopause (age at onset); LIHC cis rs9616064 0.506 rs2542038 chr22:47059282 C/T cg25730555 chr22:47059586 GRAMD4 0.36 6.04 0.31 3.98e-9 Urate levels in obese individuals; LIHC trans rs2262909 0.962 rs11669110 chr19:22296485 A/G cg05197062 chr11:11642011 GALNTL4 0.45 6.7 0.34 8.85e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2075371 0.932 rs11766132 chr7:133993062 T/C cg11752832 chr7:134001865 SLC35B4 0.48 6.07 0.31 3.46e-9 Mean platelet volume; LIHC cis rs8044995 0.563 rs73615919 chr16:68398862 C/T cg05110241 chr16:68378359 PRMT7 -0.82 -9.5 -0.46 3.69e-19 Schizophrenia; LIHC cis rs875971 0.929 rs6970860 chr7:65976634 A/G cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.47e-9 Aortic root size; LIHC cis rs727505 1.000 rs10233385 chr7:124498707 C/G cg23710748 chr7:124431027 NA -0.32 -5.78 -0.3 1.66e-8 Lewy body disease; LIHC cis rs4407350 0.748 rs131170 chr22:44901601 C/A cg11695653 chr22:44894386 LDOC1L -0.38 -6.54 -0.33 2.27e-10 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg14004847 chr7:1930337 MAD1L1 -0.41 -5.89 -0.3 9.26e-9 Bipolar disorder and schizophrenia; LIHC cis rs17854409 0.764 rs3761301 chr20:61494021 C/T cg05147244 chr20:61493195 TCFL5 1.28 10.3 0.49 7.83e-22 Obesity-related traits; LIHC cis rs344364 0.511 rs1742460 chr16:1945441 G/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.57 -7.34 -0.37 1.56e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs36051895 0.659 rs10974944 chr9:5070831 C/G cg02405213 chr9:5042618 JAK2 -0.67 -11.18 -0.52 6.09e-25 Pediatric autoimmune diseases; LIHC cis rs10193935 0.901 rs2286702 chr2:42555473 C/T cg27598129 chr2:42591480 NA -0.74 -11.16 -0.52 6.95e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg09417038 chr21:47716443 C21orf57 -0.49 -7.14 -0.36 5.51e-12 Testicular germ cell tumor; LIHC cis rs6754311 0.513 rs1438304 chr2:136503157 A/G cg07305463 chr2:136567211 LCT 0.39 7.22 0.36 3.4e-12 Mosquito bite size; LIHC cis rs2404602 0.692 rs4886829 chr15:77091182 G/T cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.81e-9 Blood metabolite levels; LIHC cis rs17253792 0.822 rs111467375 chr14:56046159 T/G cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs8067354 0.645 rs2173119 chr17:57859705 C/T cg02344993 chr17:57696989 CLTC 0.7 11.66 0.53 1.16e-26 Hemoglobin concentration; LIHC cis rs9814567 0.896 rs6790338 chr3:134208167 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.47 -0.56 1.16e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11758351 0.789 rs2069020 chr6:26205500 C/T cg06951627 chr6:26196580 NA 0.55 6.39 0.33 5.5e-10 Gout;Renal underexcretion gout; LIHC cis rs1577917 1.000 rs1415753 chr6:86753074 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.31 -0.37 1.84e-12 Response to antipsychotic treatment; LIHC cis rs28374715 0.662 rs28554139 chr15:41531084 C/T cg18705301 chr15:41695430 NDUFAF1 -0.9 -10.2 -0.48 1.71e-21 Ulcerative colitis; LIHC cis rs10504229 0.610 rs6993531 chr8:58147283 A/G cg11062466 chr8:58055876 NA 0.42 6.12 0.31 2.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.958 rs1335442 chr6:86466692 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -11.33 -0.52 1.78e-25 Response to antipsychotic treatment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06162493 chr17:34900563 GGNBP2 0.48 6.41 0.33 4.96e-10 Lung function (FEV1/FVC); LIHC cis rs9303401 0.704 rs740605 chr17:56604811 C/T cg25039879 chr17:56429692 SUPT4H1 0.42 5.81 0.3 1.44e-8 Cognitive test performance; LIHC cis rs12477438 0.700 rs10190421 chr2:99670711 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.85 -0.65 8.31e-43 Chronic sinus infection; LIHC trans rs1005277 0.579 rs1548255 chr10:38417193 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.25 -0.52 3.46e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9457247 0.967 rs424185 chr6:167410907 C/T cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC cis rs74544699 1.000 rs4082827 chr4:74831180 A/C cg02530824 chr4:74847766 PF4 -0.66 -7.51 -0.38 5.17e-13 Growth-regulated protein alpha levels; LIHC trans rs877282 0.583 rs11253425 chr10:815173 G/A cg22713356 chr15:30763199 NA 0.85 7.27 0.37 2.44e-12 Uric acid levels; LIHC cis rs7980687 0.596 rs1727319 chr12:123701353 T/C cg00376283 chr12:123451042 ABCB9 0.69 10.43 0.49 2.75e-22 Height;Educational attainment;Head circumference (infant); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg02381965 chr2:3418480 TTC15 0.53 6.6 0.34 1.57e-10 Lung function (FEV1); LIHC cis rs7635838 0.827 rs4273358 chr3:11415160 T/G cg00170343 chr3:11313890 ATG7 0.44 7.03 0.36 1.1e-11 HDL cholesterol; LIHC cis rs17826219 0.706 rs57698184 chr17:29064918 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.33 0.41 1.98e-15 Body mass index; LIHC cis rs35306767 0.855 rs12771179 chr10:872347 A/G cg10556349 chr10:835070 NA 0.67 5.85 0.3 1.13e-8 Eosinophil percentage of granulocytes; LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.55 7.73 0.39 1.19e-13 Lymphocyte counts; LIHC cis rs78456975 0.628 rs13426896 chr2:1554768 C/T cg01028140 chr2:1542097 TPO -0.61 -7.77 -0.39 9.01e-14 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg15691649 chr6:25882328 NA -0.62 -7.83 -0.39 5.98e-14 Intelligence (multi-trait analysis); LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg25894440 chr7:65020034 NA 0.4 6.27 0.32 1.12e-9 Calcium levels; LIHC cis rs6500602 0.727 rs6500607 chr16:4503631 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.37 5.73 0.3 2.15e-8 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09311052 chr1:154531418 UBE2Q1 0.41 7.09 0.36 7.5e-12 Cognitive function; LIHC cis rs12701220 0.803 rs12701432 chr7:1052453 C/T cg00990874 chr7:1149470 C7orf50 -0.66 -9.19 -0.45 3.86e-18 Bronchopulmonary dysplasia; LIHC cis rs4819052 0.959 rs8130866 chr21:46672112 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 10.03 0.48 6.31e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs35306767 0.761 rs11253560 chr10:1047226 T/G cg26597838 chr10:835615 NA 0.9 8.69 0.43 1.54e-16 Eosinophil percentage of granulocytes; LIHC cis rs7659604 0.539 rs11098648 chr4:122759872 C/T cg20573242 chr4:122745356 CCNA2 0.53 7.79 0.39 8.06e-14 Type 2 diabetes; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg15641998 chr4:88312323 HSD17B11 -0.28 -6.17 -0.32 1.88e-9 Oropharynx cancer; LIHC cis rs9633740 1.000 rs6586028 chr10:82253984 C/T cg01528321 chr10:82214614 TSPAN14 0.94 12.08 0.55 3.14e-28 Post bronchodilator FEV1; LIHC cis rs4803468 0.904 rs60781668 chr19:41944842 A/T cg09537434 chr19:41945824 ATP5SL 1.01 20.35 0.74 6.81e-61 Height; LIHC cis rs28374715 0.532 rs28463309 chr15:41666716 A/G cg18705301 chr15:41695430 NDUFAF1 -1.2 -18.07 -0.7 1e-51 Ulcerative colitis; LIHC cis rs7481584 0.624 rs412149 chr11:3069943 G/A cg25174290 chr11:3078921 CARS -0.42 -6.31 -0.32 8.58e-10 Calcium levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22596738 chr1:236688128 LGALS8 0.51 7.71 0.38 1.41e-13 Cognitive function; LIHC cis rs6089829 0.962 rs1116450 chr20:61658210 T/C cg08564027 chr20:61660810 NA 0.4 7.71 0.38 1.38e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg05564831 chr3:52568323 NT5DC2 0.37 6.03 0.31 4.19e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs892961 0.932 rs7222170 chr17:75413096 G/A cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs868036 0.718 rs28463100 chr15:68078769 T/C cg24579218 chr15:68104479 NA -0.34 -5.94 -0.31 7.12e-9 Restless legs syndrome; LIHC cis rs918629 0.530 rs3777192 chr5:95246867 G/A cg10483112 chr5:95245456 ELL2 -0.37 -6.89 -0.35 2.77e-11 IgG glycosylation; LIHC cis rs4319547 0.695 rs55834409 chr12:122862560 C/G cg05707623 chr12:122985044 ZCCHC8 0.54 7.15 0.36 5.15e-12 Body mass index; LIHC cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg05368731 chr17:41323189 NBR1 0.72 12.47 0.56 1.08e-29 Menopause (age at onset); LIHC cis rs2933343 0.951 rs789251 chr3:128576770 G/A cg25356066 chr3:128598488 ACAD9 0.55 7.24 0.36 3.06e-12 IgG glycosylation; LIHC cis rs1707322 0.656 rs9429172 chr1:46092476 C/G cg24296786 chr1:45957014 TESK2 0.4 5.75 0.3 1.99e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2239547 0.657 rs6445539 chr3:52874296 G/A cg11645453 chr3:52864694 ITIH4 0.36 9.36 0.45 1.09e-18 Schizophrenia; LIHC cis rs7715806 0.500 rs17649350 chr5:75006156 C/T cg00601450 chr5:74908170 NA -0.57 -6.96 -0.35 1.72e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8072100 0.935 rs78737171 chr17:45668760 A/T cg08085267 chr17:45401833 C17orf57 0.41 6.11 0.31 2.68e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs17685 0.753 rs3757593 chr7:75678735 G/A cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.75 -0.71 1.96e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs28647808 0.881 rs4246171 chr9:136264731 G/A cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs1018836 0.632 rs7002775 chr8:91476765 C/T cg16814680 chr8:91681699 NA 0.38 6.16 0.32 2e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs8067354 0.958 rs2333563 chr17:57839568 A/G cg13753209 chr17:57696993 CLTC 0.58 8.76 0.43 9.51e-17 Hemoglobin concentration; LIHC cis rs644799 1.000 rs488246 chr11:95560473 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11098499 0.866 rs3756156 chr4:120524841 G/A cg09307838 chr4:120376055 NA 0.73 11.07 0.51 1.5e-24 Corneal astigmatism; LIHC cis rs2281558 0.793 rs6115227 chr20:25591377 A/C cg13962466 chr20:25176127 ENTPD6 -0.41 -5.84 -0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction);Calcium levels; LIHC cis rs67460515 0.892 rs11711413 chr3:160998910 C/G cg03342759 chr3:160939853 NMD3 -0.67 -10.11 -0.48 3.36e-21 Parkinson's disease; LIHC cis rs798554 0.796 rs2158694 chr7:2863443 T/G cg04166393 chr7:2884313 GNA12 0.45 6.17 0.32 1.89e-9 Height; LIHC cis rs17711722 0.690 rs116823227 chr7:65331001 A/G cg11764359 chr7:65958608 NA 0.7 8.57 0.42 3.59e-16 Calcium levels; LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg09033563 chr22:24373618 LOC391322 -0.48 -6.79 -0.34 4.93e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg17554472 chr22:41940697 POLR3H -0.56 -6.11 -0.31 2.77e-9 Vitiligo; LIHC cis rs7772486 0.719 rs7753770 chr6:146066161 G/A cg23711669 chr6:146136114 FBXO30 -0.73 -13.51 -0.59 1.28e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs2279817 0.863 rs871088 chr1:18017558 A/G cg21791023 chr1:18019539 ARHGEF10L 0.68 8.05 0.4 1.36e-14 Neuroticism; LIHC cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg07061783 chr6:25882402 NA -0.48 -6.73 -0.34 7.1e-11 Blood metabolite levels; LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.54 -7.57 -0.38 3.5e-13 Lymphocyte counts; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.63 0.46 1.44e-19 Height; LIHC cis rs16866061 0.515 rs114968850 chr2:225352461 C/G cg22509189 chr2:225307070 NA -0.5 -7.46 -0.37 7.2e-13 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs6960043 0.791 rs2191346 chr7:15053878 C/G cg19272540 chr7:15055459 NA -0.25 -6.85 -0.35 3.53e-11 Type 2 diabetes; LIHC cis rs9303280 0.836 rs11557467 chr17:38028634 G/T cg11212589 chr17:38028394 ZPBP2 0.38 7.98 0.4 2.22e-14 Self-reported allergy; LIHC cis rs6964587 1.000 rs10245095 chr7:91710845 A/G cg17063962 chr7:91808500 NA 1.03 20.53 0.74 1.35e-61 Breast cancer; LIHC cis rs2050392 0.965 rs1543725 chr10:30698873 A/G cg25182066 chr10:30743637 MAP3K8 -0.43 -6.93 -0.35 2.06e-11 Inflammatory bowel disease; LIHC cis rs858239 0.539 rs10225608 chr7:23188908 A/G cg23682824 chr7:23144976 KLHL7 0.46 6.96 0.35 1.71e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs6446731 0.500 rs2858085 chr4:3271226 T/G cg06533319 chr4:3265114 C4orf44 0.31 5.76 0.3 1.9e-8 Mean platelet volume; LIHC cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg22974920 chr21:40686053 BRWD1 -0.41 -5.92 -0.3 7.72e-9 Cognitive function; LIHC cis rs28735056 0.584 rs11664834 chr18:77644876 G/T cg20368463 chr18:77673604 PQLC1 0.57 8.08 0.4 1.14e-14 Schizophrenia; LIHC cis rs10847980 0.590 rs2292131 chr12:123332354 C/T cg18912006 chr12:123335444 HIP1R 0.76 7.79 0.39 8.13e-14 Adiponectin levels; LIHC cis rs611744 0.837 rs399131 chr8:109105285 C/T cg21045802 chr8:109455806 TTC35 -0.46 -7.9 -0.39 3.76e-14 Dupuytren's disease; LIHC cis rs4919087 0.561 rs61861844 chr10:99064171 G/A cg25902810 chr10:99078978 FRAT1 -0.63 -7.39 -0.37 1.13e-12 Monocyte count; LIHC trans rs875971 0.545 rs11766183 chr7:65839160 G/C cg26939375 chr7:64535504 NA 0.4 6.29 0.32 9.67e-10 Aortic root size; LIHC cis rs412000 0.553 rs2680702 chr17:56431549 A/G cg25039879 chr17:56429692 SUPT4H1 0.56 7.53 0.38 4.43e-13 Primary tooth development (time to first tooth eruption); LIHC cis rs6424115 0.830 rs6672157 chr1:24198840 C/G cg10978503 chr1:24200527 CNR2 0.34 8.06 0.4 1.33e-14 Immature fraction of reticulocytes; LIHC trans rs2727020 0.634 rs11040331 chr11:49345726 T/C cg18944383 chr4:111397179 ENPEP 0.31 6.86 0.35 3.24e-11 Coronary artery disease; LIHC cis rs8060686 0.516 rs7194894 chr16:68145062 C/T cg05110241 chr16:68378359 PRMT7 -0.57 -6.61 -0.34 1.48e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs9649465 1.000 rs9641715 chr7:123348623 A/G cg03229431 chr7:123269106 ASB15 -0.37 -8.0 -0.4 1.96e-14 Migraine; LIHC cis rs7107174 1.000 rs10899475 chr11:78051610 T/C cg02023728 chr11:77925099 USP35 0.43 8.22 0.41 4.21e-15 Testicular germ cell tumor; LIHC cis rs11077998 0.840 rs9894993 chr17:80481088 T/C cg10255544 chr17:80519551 FOXK2 0.49 8.88 0.43 3.95e-17 Reticulocyte fraction of red cells; LIHC cis rs11673344 0.734 rs496872 chr19:37439481 C/T cg27390819 chr19:37464633 NA -0.52 -6.22 -0.32 1.42e-9 Obesity-related traits; LIHC cis rs7572733 0.555 rs700671 chr2:198690001 T/C cg00792783 chr2:198669748 PLCL1 0.45 6.7 0.34 8.84e-11 Dermatomyositis; LIHC cis rs4555082 0.794 rs2735829 chr14:105708472 C/T cg06808227 chr14:105710500 BRF1 -0.49 -6.14 -0.32 2.27e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg20887711 chr4:1340912 KIAA1530 0.79 12.29 0.55 5.29e-29 Longevity; LIHC cis rs7927771 0.524 rs2869024 chr11:47674101 G/A cg20307385 chr11:47447363 PSMC3 -0.75 -11.32 -0.52 1.84e-25 Subjective well-being; LIHC trans rs11098499 0.731 rs10015579 chr4:120271802 T/C cg25214090 chr10:38739885 LOC399744 0.45 7.48 0.37 6.21e-13 Corneal astigmatism; LIHC cis rs7312933 0.618 rs7315968 chr12:42637086 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 8.02 0.4 1.73e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1865760 0.566 rs7772312 chr6:26049616 G/C cg18357526 chr6:26021779 HIST1H4A 0.48 7.06 0.36 9.55e-12 Height; LIHC cis rs1868673 0.503 rs4129188 chr3:150241673 C/T cg10752315 chr3:150238463 NA 0.3 5.92 0.3 7.73e-9 Waist circumference; LIHC cis rs2576037 0.507 rs2571019 chr18:44585287 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.59 -8.86 -0.43 4.49e-17 Personality dimensions; LIHC cis rs7615952 0.673 rs34209763 chr3:125599595 G/A cg05084668 chr3:125655381 ALG1L -0.8 -10.87 -0.51 8.03e-24 Blood pressure (smoking interaction); LIHC trans rs875971 1.000 rs10215948 chr7:65747786 G/A cg10756647 chr7:56101905 PSPH -0.44 -6.49 -0.33 3.03e-10 Aortic root size; LIHC cis rs12220238 1.000 rs10824088 chr10:75921490 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.4 0.33 5.2e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs4927850 0.709 rs6765762 chr3:195652851 G/A cg00031303 chr3:195681400 NA 0.55 7.62 0.38 2.53e-13 Pancreatic cancer; LIHC cis rs17685 0.558 rs60787921 chr7:75792844 C/A cg01364799 chr7:75623366 TMEM120A -0.52 -7.74 -0.39 1.13e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9513627 1.000 rs7334844 chr13:100121047 G/C cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs10911232 0.507 rs7547953 chr1:183031641 T/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.54 0.5 1.15e-22 Hypertriglyceridemia; LIHC trans rs7246657 0.943 rs35540940 chr19:38008235 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.04 0.31 4.11e-9 Coronary artery calcification; LIHC cis rs9649465 1.000 rs1006764 chr7:123337873 C/T cg03229431 chr7:123269106 ASB15 -0.37 -7.99 -0.4 2.04e-14 Migraine; LIHC cis rs13064411 0.735 rs7631138 chr3:113231925 A/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg23205692 chr1:25664452 TMEM50A -0.37 -6.01 -0.31 4.67e-9 Erythrocyte sedimentation rate; LIHC cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.7 0.69 3.05e-50 Gut microbiome composition (summer); LIHC cis rs10876993 0.890 rs1689597 chr12:58051886 G/A cg18357645 chr12:58087776 OS9 0.53 8.6 0.42 2.93e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs34779708 0.966 rs11010129 chr10:35510822 T/C cg03585969 chr10:35415529 CREM 0.87 13.06 0.58 6.74e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2834188 1.000 rs2834188 chr21:34689253 A/G cg14352951 chr21:34696688 IFNAR1 0.47 6.53 0.33 2.35e-10 Narcolepsy; LIHC cis rs2075371 1.000 rs1862050 chr7:133980999 T/C cg20476274 chr7:133979776 SLC35B4 0.75 12.65 0.56 2.3e-30 Mean platelet volume; LIHC cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.81 0.3 1.39e-8 Menopause (age at onset); LIHC cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg12311346 chr5:56204834 C5orf35 -0.5 -6.52 -0.33 2.56e-10 Initial pursuit acceleration; LIHC cis rs12530845 0.943 rs55889179 chr7:135331631 C/T cg23117316 chr7:135346802 PL-5283 -0.34 -5.78 -0.3 1.72e-8 Red blood cell traits; LIHC cis rs72653721 0.617 rs57940154 chr6:11035425 C/T cg13562911 chr6:11044106 ELOVL2 0.39 5.79 0.3 1.56e-8 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs875971 1.000 rs778710 chr7:65854834 T/C cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs9660180 0.620 rs34298494 chr1:1663402 A/C cg13866156 chr1:1669148 SLC35E2 0.74 11.29 0.52 2.39e-25 Body mass index; LIHC cis rs4555082 0.874 rs2816612 chr14:105723103 C/T cg13114125 chr14:105738426 BRF1 -0.72 -9.35 -0.45 1.21e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs629922 0.671 rs1184748 chr11:114037061 A/G cg01914181 chr11:114070210 ZBTB16 0.41 5.92 0.3 7.93e-9 Paneth cell defects in Crohn's disease; LIHC cis rs1580019 0.520 rs13228793 chr7:32711465 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.87 13.17 0.58 2.48e-32 Cognitive ability; LIHC cis rs911119 0.908 rs8114619 chr20:23601813 G/T cg16589663 chr20:23618590 CST3 0.73 7.67 0.38 1.75e-13 Chronic kidney disease; LIHC cis rs595982 0.661 rs606400 chr19:49371498 T/C cg21252483 chr19:49399788 TULP2 -0.45 -7.54 -0.38 4.28e-13 Red cell distribution width; LIHC cis rs11673344 0.704 rs484001 chr19:37422222 C/T cg27390819 chr19:37464633 NA -0.5 -6.09 -0.31 3.05e-9 Obesity-related traits; LIHC trans rs116095464 0.558 rs6881920 chr5:222411 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs10197940 0.624 rs4461258 chr2:152429679 A/G cg06191203 chr2:152266755 RIF1 0.43 7.33 0.37 1.7e-12 Lung cancer; LIHC cis rs7937682 0.921 rs7130753 chr11:111470567 C/T cg09085632 chr11:111637200 PPP2R1B 0.86 9.82 0.47 3.36e-20 Primary sclerosing cholangitis; LIHC cis rs7216064 1.000 rs7223930 chr17:65842186 G/A cg12091567 chr17:66097778 LOC651250 -0.67 -9.78 -0.47 4.54e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs1863824 0.625 rs11202024 chr10:88168024 C/A cg07322936 chr10:88137208 NA -0.47 -5.99 -0.31 5.43e-9 Schizophrenia; LIHC cis rs9918079 0.542 rs6414765 chr4:15626493 G/A cg04067612 chr4:15429572 C1QTNF7 -0.27 -5.75 -0.3 2.03e-8 Obesity-related traits; LIHC cis rs208515 0.556 rs10455193 chr6:66691456 G/A cg07460842 chr6:66804631 NA 0.79 8.97 0.44 1.94e-17 Exhaled nitric oxide levels; LIHC cis rs1030877 0.521 rs2576747 chr2:105978676 A/T cg02079111 chr2:105885981 TGFBRAP1 0.52 8.4 0.41 1.23e-15 Obesity-related traits; LIHC cis rs858239 0.863 rs274058 chr7:23391509 C/G cg00469287 chr7:23338798 C7orf30 0.48 6.48 0.33 3.25e-10 Cerebrospinal fluid biomarker levels; LIHC trans rs1493916 0.748 rs1845386 chr18:31318256 C/G cg27147174 chr7:100797783 AP1S1 -0.49 -6.71 -0.34 8.13e-11 Life satisfaction; LIHC cis rs13108904 0.901 rs6851528 chr4:1296009 G/A cg25897951 chr4:1244024 CTBP1;C4orf42 -0.37 -5.72 -0.3 2.34e-8 Obesity-related traits; LIHC cis rs7208859 0.573 rs8078182 chr17:29149664 C/T cg14067834 chr17:29058358 SUZ12P 0.62 6.25 0.32 1.25e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600806 0.850 rs10745355 chr1:109951711 T/C cg23091122 chr1:110024289 SYPL2 -0.45 -5.96 -0.31 6.44e-9 Intelligence (multi-trait analysis); LIHC cis rs11030122 0.673 rs11030660 chr11:4043268 T/C cg18678763 chr11:4115507 RRM1 -0.57 -8.38 -0.41 1.43e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs796364 1.000 rs11895190 chr2:200838613 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.7 -8.26 -0.41 3.21e-15 Schizophrenia; LIHC cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.77 -0.5 1.68e-23 Platelet count; LIHC cis rs8017423 0.935 rs2149653 chr14:90669333 G/A cg04374321 chr14:90722782 PSMC1 0.71 13.52 0.59 1.11e-33 Mortality in heart failure; LIHC cis rs2625529 0.775 rs62023342 chr15:72161305 A/C cg16672083 chr15:72433130 SENP8 -0.31 -5.82 -0.3 1.39e-8 Red blood cell count; LIHC trans rs4720750 0.502 rs4140803 chr7:7710369 A/C cg27619457 chr5:1298761 NA 0.42 6.54 0.33 2.24e-10 Neuroticism; LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs4906332 1.000 rs55731474 chr14:103878481 G/A cg19000871 chr14:103996768 TRMT61A -0.42 -7.25 -0.37 2.77e-12 Coronary artery disease; LIHC cis rs763121 0.819 rs8137829 chr22:39061030 G/A cg06022373 chr22:39101656 GTPBP1 0.66 11.49 0.53 4.72e-26 Menopause (age at onset); LIHC cis rs8077889 0.719 rs57227660 chr17:41858984 T/C cg26893861 chr17:41843967 DUSP3 1.06 18.38 0.7 5.89e-53 Triglycerides; LIHC cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC cis rs12594515 0.694 rs2068295 chr15:45985546 T/C cg01629716 chr15:45996671 NA 0.51 9.24 0.45 2.66e-18 Waist circumference;Weight; LIHC cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg11764359 chr7:65958608 NA 0.57 5.85 0.3 1.13e-8 Diabetic kidney disease; LIHC cis rs3806843 0.801 rs2531358 chr5:140117437 A/G cg16179182 chr5:140090404 VTRNA1-1 0.35 5.86 0.3 1.08e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg00149659 chr3:10157352 C3orf10 0.68 6.93 0.35 2.11e-11 Alzheimer's disease; LIHC cis rs3770081 1.000 rs2278086 chr2:86281905 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.95 -11.58 -0.53 2.24e-26 Facial emotion recognition (sad faces); LIHC cis rs7726839 0.574 rs72705014 chr5:619815 C/G cg09021430 chr5:549028 NA -0.42 -8.48 -0.42 7.01e-16 Obesity-related traits; LIHC cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg02503808 chr4:7069936 GRPEL1 0.79 11.81 0.54 3.14e-27 Monocyte percentage of white cells; LIHC cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.07 -0.31 3.4e-9 Colorectal cancer; LIHC cis rs17685 0.753 rs10476 chr7:75696420 C/T cg01364799 chr7:75623366 TMEM120A 0.48 7.22 0.36 3.33e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8062405 0.964 rs78613234 chr16:28839425 T/C cg07451762 chr16:28383216 NA 0.32 6.12 0.31 2.56e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12477438 0.798 rs10167015 chr2:99570707 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.08 -15.36 -0.64 7.54e-41 Chronic sinus infection; LIHC cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.89 0.57 2.95e-31 Alzheimer's disease; LIHC cis rs9419702 0.568 rs7920966 chr10:133555185 G/T cg04492858 chr10:133558786 NA 0.44 6.74 0.34 6.88e-11 Survival in rectal cancer; LIHC cis rs703842 1.000 rs3782130 chr12:58161898 G/C cg04478727 chr12:58166393 METTL1;FAM119B 0.86 13.98 0.6 1.85e-35 Multiple sclerosis; LIHC cis rs422249 0.504 rs174538 chr11:61560081 G/A cg27386326 chr11:61587980 NA 0.69 14.12 0.61 5.62e-36 Trans fatty acid levels; LIHC cis rs6430585 0.528 rs75524146 chr2:136725459 C/T cg25344623 chr2:136566232 LCT -0.37 -5.92 -0.3 7.94e-9 Corneal structure; LIHC cis rs2304069 0.826 rs184960 chr5:149343370 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.69 -9.01 -0.44 1.51e-17 HIV-1 control; LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.95 0.57 1.78e-31 Prudent dietary pattern; LIHC cis rs12928939 0.517 rs11865456 chr16:71969497 C/T cg03805757 chr16:71968109 PKD1L3 -0.91 -13.05 -0.58 7.02e-32 Post bronchodilator FEV1; LIHC cis rs11864453 0.713 rs6680 chr16:72146570 T/C cg16558253 chr16:72132732 DHX38 -0.5 -8.16 -0.4 6.65e-15 Fibrinogen levels; LIHC cis rs288342 0.832 rs288299 chr2:183657289 C/T cg02625481 chr2:183667124 NA -0.29 -5.99 -0.31 5.43e-9 Recurrent major depressive disorder; LIHC cis rs2066819 1.000 rs11575229 chr12:56750737 C/T cg26734620 chr12:56694298 CS 1.21 10.14 0.48 2.67e-21 Psoriasis vulgaris; LIHC cis rs763121 0.819 rs5757133 chr22:38947835 A/G cg06022373 chr22:39101656 GTPBP1 -0.63 -10.77 -0.5 1.69e-23 Menopause (age at onset); LIHC cis rs921968 0.643 rs3770218 chr2:219525335 C/T cg02985541 chr2:219472218 PLCD4 0.44 8.12 0.4 8.52e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs4253772 0.591 rs12167567 chr22:46659942 G/C cg24881330 chr22:46731750 TRMU 0.55 5.83 0.3 1.3e-8 LDL cholesterol;Cholesterol, total; LIHC cis rs12220238 0.822 rs7919517 chr10:76111355 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs3820500 0.543 rs1290543 chr1:118036420 A/G cg20383390 chr1:117909022 MAN1A2 -0.46 -6.03 -0.31 4.33e-9 Pneumonia; LIHC cis rs1023500 0.505 rs2143139 chr22:42614401 G/C cg15557168 chr22:42548783 NA -0.34 -5.87 -0.3 1.06e-8 Schizophrenia; LIHC cis rs61712019 0.599 rs17595137 chr2:77728001 G/C cg11252801 chr2:77748917 LRRTM4 0.45 6.31 0.32 8.65e-10 Schizophrenia; LIHC cis rs700651 0.821 rs770661 chr2:198725444 A/G cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Intracranial aneurysm; LIHC cis rs9993613 1.000 rs753944 chr4:73449917 T/C cg15102770 chr4:73434591 ADAMTS3 -0.38 -6.06 -0.31 3.58e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg27432699 chr2:27873401 GPN1 -0.54 -7.84 -0.39 5.98e-14 Total body bone mineral density; LIHC cis rs35306767 0.807 rs1013505 chr10:953273 C/T cg20503657 chr10:835505 NA 1.0 10.97 0.51 3.33e-24 Eosinophil percentage of granulocytes; LIHC cis rs950169 0.580 rs4603535 chr15:85173872 C/T cg03959625 chr15:84868606 LOC388152 0.44 6.08 0.31 3.13e-9 Schizophrenia; LIHC cis rs2635047 0.638 rs1434529 chr18:44730142 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.93 0.31 7.21e-9 Educational attainment; LIHC cis rs3015497 0.616 rs34061700 chr14:51084860 G/A cg09863266 chr14:51125203 SAV1 -0.39 -6.18 -0.32 1.8e-9 Mean platelet volume; LIHC cis rs8084351 0.512 rs11664776 chr18:50797415 T/C cg24270629 chr18:50823537 DCC -0.52 -7.96 -0.4 2.63e-14 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs4727027 0.901 rs1534197 chr7:148771970 T/C cg23583168 chr7:148888333 NA -0.67 -9.23 -0.45 2.84e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01357671 chr17:3626806 ITGAE;GSG2 0.43 6.27 0.32 1.06e-9 Lung function (FEV1/FVC); LIHC cis rs11098499 0.863 rs28718422 chr4:120466304 C/A cg09307838 chr4:120376055 NA 0.76 11.71 0.54 7.22e-27 Corneal astigmatism; LIHC cis rs9902453 0.740 rs2244247 chr17:28110174 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs3796352 1.000 rs13076033 chr3:52898427 T/C cg04865290 chr3:52927548 TMEM110 -0.59 -6.69 -0.34 9.1e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg19318889 chr4:1322082 MAEA 0.43 5.95 0.31 6.65e-9 Obesity-related traits; LIHC cis rs2404602 0.647 rs11072626 chr15:77090826 A/G cg03037974 chr15:76606532 NA -0.61 -10.23 -0.48 1.35e-21 Blood metabolite levels; LIHC trans rs1814175 0.527 rs7110797 chr11:49644096 T/C cg15704280 chr7:45808275 SEPT13 -0.79 -11.69 -0.53 8.82e-27 Height; LIHC cis rs2404602 0.552 rs11072613 chr15:76961526 A/C cg23625390 chr15:77176239 SCAPER -0.44 -6.82 -0.35 4.07e-11 Blood metabolite levels; LIHC cis rs13108904 0.517 rs4974551 chr4:1336410 C/A cg00684032 chr4:1343700 KIAA1530 0.59 8.71 0.43 1.36e-16 Obesity-related traits; LIHC cis rs6952808 1.000 rs4721121 chr7:1892565 A/G cg04267008 chr7:1944627 MAD1L1 -0.58 -8.83 -0.43 5.66e-17 Bipolar disorder and schizophrenia; LIHC cis rs12477438 0.798 rs1453561 chr2:99613924 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.68 -0.53 9.81e-27 Chronic sinus infection; LIHC cis rs77106637 0.929 rs77464186 chr11:72460398 A/C cg03713592 chr11:72463424 ARAP1 1.17 10.73 0.5 2.37e-23 Type 2 diabetes; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.32 -0.32 8.17e-10 Diastolic blood pressure; LIHC cis rs8017423 0.607 rs10142482 chr14:90848280 G/T cg14092571 chr14:90743983 NA 0.45 6.36 0.33 6.62e-10 Mortality in heart failure; LIHC cis rs9534288 0.762 rs1571052 chr13:46554849 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg13944838 chr5:179740914 GFPT2 -0.5 -7.14 -0.36 5.69e-12 Height; LIHC cis rs13108904 0.539 rs13141169 chr4:1340353 C/T cg13395646 chr4:1353034 KIAA1530 -0.85 -12.99 -0.57 1.27e-31 Obesity-related traits; LIHC cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg17971929 chr21:40555470 PSMG1 0.53 7.89 0.39 4.22e-14 Cognitive function; LIHC cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg12311346 chr5:56204834 C5orf35 -0.5 -6.52 -0.33 2.56e-10 Initial pursuit acceleration; LIHC trans rs1814175 0.645 rs4625470 chr11:49983769 T/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs11098499 0.644 rs28787668 chr4:120554687 G/A cg09307838 chr4:120376055 NA 0.67 10.26 0.49 1.05e-21 Corneal astigmatism; LIHC cis rs9916302 0.851 rs12947620 chr17:37605364 T/C cg00129232 chr17:37814104 STARD3 -0.41 -6.61 -0.34 1.45e-10 Glomerular filtration rate (creatinine); LIHC cis rs447735 0.587 rs258335 chr16:89720944 G/A cg04240660 chr16:89714849 CHMP1A -0.51 -8.54 -0.42 4.5e-16 Hemoglobin concentration; LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg06873352 chr17:61820015 STRADA 0.73 13.08 0.58 5.59e-32 Prudent dietary pattern; LIHC cis rs9392556 0.600 rs2326408 chr6:4119516 A/G cg10424681 chr6:4079350 C6orf201;C6orf146 0.24 5.77 0.3 1.82e-8 Blood metabolite levels; LIHC cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.59 -0.34 1.67e-10 Gut microbiome composition (summer); LIHC trans rs877282 0.945 rs71491303 chr10:772884 G/T cg22713356 chr15:30763199 NA 1.23 10.89 0.51 6.83e-24 Uric acid levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15044384 chr19:18118666 ARRDC2 -0.52 -6.21 -0.32 1.54e-9 Systolic blood pressure; LIHC cis rs9814567 0.712 rs9838889 chr3:134332311 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4819052 0.851 rs2838849 chr21:46671027 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.77 0.39 9.12e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7116495 1.000 rs7930721 chr11:71737481 C/A cg26138937 chr11:71823887 C11orf51 -0.81 -8.04 -0.4 1.43e-14 Severe influenza A (H1N1) infection; LIHC cis rs11608355 0.545 rs33997929 chr12:109912064 C/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs7520050 0.872 rs1707308 chr1:46604315 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.45 6.74 0.34 6.94e-11 Red blood cell count;Reticulocyte count; LIHC cis rs11190604 1.000 rs11190589 chr10:102275471 A/G cg07080220 chr10:102295463 HIF1AN 0.55 7.99 0.4 2.07e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9814567 0.896 rs6794258 chr3:134344505 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.59 -9.88 -0.47 2.04e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4900538 0.855 rs9788420 chr14:102839338 A/G cg18135206 chr14:102964638 TECPR2 -0.74 -11.65 -0.53 1.25e-26 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg25894440 chr7:65020034 NA 0.52 6.05 0.31 3.73e-9 Diabetic kidney disease; LIHC cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg03517284 chr6:25882590 NA -0.63 -8.86 -0.43 4.45e-17 Blood metabolite levels; LIHC cis rs56104184 0.775 rs56146968 chr19:49398847 A/G cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs12908161 0.959 rs2175567 chr15:85200946 C/G cg03959625 chr15:84868606 LOC388152 0.45 6.28 0.32 1.06e-9 Schizophrenia; LIHC cis rs7107174 1.000 rs2292572 chr11:78052864 G/T cg02023728 chr11:77925099 USP35 0.44 8.49 0.42 6.61e-16 Testicular germ cell tumor; LIHC cis rs17253792 0.822 rs74609892 chr14:56053002 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.15e-10 Putamen volume; LIHC trans rs4650994 0.625 rs6681354 chr1:178526279 A/G cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7772486 0.625 rs2050027 chr6:146116113 C/G cg05347473 chr6:146136440 FBXO30 -0.36 -5.8 -0.3 1.5e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1448094 0.512 rs7303330 chr12:86255123 G/A cg02569458 chr12:86230093 RASSF9 0.46 6.22 0.32 1.43e-9 Major depressive disorder; LIHC cis rs9467773 0.935 rs1056668 chr6:26510605 C/T cg09904177 chr6:26538194 HMGN4 0.56 10.84 0.51 1.02e-23 Intelligence (multi-trait analysis); LIHC cis rs801193 0.569 rs6978178 chr7:66123084 G/A cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg03264133 chr6:25882463 NA 0.57 7.67 0.38 1.76e-13 Blood metabolite levels; LIHC cis rs6748734 1.000 rs4344931 chr2:241818527 A/C cg09990169 chr2:241835740 C2orf54 -0.66 -9.36 -0.45 1.06e-18 Urinary metabolites; LIHC cis rs2067615 0.579 rs1811458 chr12:107203683 G/A cg15890332 chr12:107067104 RFX4 0.26 6.19 0.32 1.72e-9 Heart rate; LIHC cis rs7552404 1.000 rs4949879 chr1:76237143 G/A cg10523679 chr1:76189770 ACADM 0.65 8.69 0.43 1.56e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs986417 1.000 rs1254291 chr14:60863570 A/T cg27398547 chr14:60952738 C14orf39 -0.71 -8.29 -0.41 2.54e-15 Gut microbiota (bacterial taxa); LIHC cis rs2574704 0.781 rs2574721 chr3:11660035 A/G cg15876825 chr3:11651881 VGLL4 0.49 7.9 0.39 3.94e-14 Body mass index; LIHC cis rs4908768 0.906 rs11121213 chr1:8728187 C/A cg20416874 chr1:8611966 RERE 0.5 7.11 0.36 6.92e-12 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs10838687 0.736 rs4647726 chr11:47245494 A/T cg25783544 chr11:47291846 MADD 0.49 6.15 0.32 2.11e-9 Proinsulin levels; LIHC cis rs9818758 0.607 rs34326553 chr3:49134429 A/G cg00383909 chr3:49044727 WDR6 0.84 7.15 0.36 5.14e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg13819250 chr17:41560934 DHX8 -0.41 -6.08 -0.31 3.25e-9 Calcium levels; LIHC trans rs875971 0.545 rs316306 chr7:65618674 G/A cg26939375 chr7:64535504 NA -0.41 -6.47 -0.33 3.36e-10 Aortic root size; LIHC cis rs7786877 0.723 rs6969697 chr7:100209604 G/A cg00334542 chr7:100209784 MOSPD3 -0.73 -7.55 -0.38 3.89e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg19635926 chr16:89946313 TCF25 0.55 7.44 0.37 8.03e-13 Skin colour saturation; LIHC cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg11279151 chr3:101281821 RG9MTD1 -0.52 -7.32 -0.37 1.79e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg02990361 chr1:107599529 PRMT6 0.64 10.45 0.49 2.24e-22 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs8017423 0.874 rs2149656 chr14:90707508 A/C cg14092571 chr14:90743983 NA -0.37 -5.82 -0.3 1.37e-8 Mortality in heart failure; LIHC trans rs7618501 0.633 rs4688755 chr3:50064424 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.58 -9.57 -0.46 2.3e-19 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.752 rs11211169 chr1:46166709 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg16132339 chr22:24313637 DDTL;DDT 0.61 10.14 0.48 2.65e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs651907 0.514 rs34301719 chr3:101417993 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.69 10.88 0.51 7.22e-24 Colorectal cancer; LIHC cis rs36051895 0.623 rs2208685 chr9:5251758 T/C cg02405213 chr9:5042618 JAK2 -0.62 -9.89 -0.47 1.84e-20 Pediatric autoimmune diseases; LIHC trans rs11098499 0.954 rs878373 chr4:120237484 A/T cg25214090 chr10:38739885 LOC399744 0.59 9.5 0.46 3.65e-19 Corneal astigmatism; LIHC cis rs1267303 0.537 rs59935547 chr1:47001423 A/G cg25110126 chr1:46999211 NA 0.41 6.09 0.31 3.01e-9 Monobrow; LIHC cis rs5753037 0.809 rs2057882 chr22:30217827 A/T cg01021169 chr22:30184971 ASCC2 -0.36 -6.74 -0.34 6.72e-11 Type 1 diabetes; LIHC cis rs1707322 0.686 rs2991977 chr1:46053683 G/A cg03146154 chr1:46216737 IPP -0.55 -9.21 -0.45 3.4e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs174601 0.861 rs174550 chr11:61571478 T/C cg07689907 chr11:61582574 FADS1 0.39 5.77 0.3 1.78e-8 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs2180341 0.960 rs7756884 chr6:127684018 A/G cg24812749 chr6:127587940 RNF146 1.05 15.56 0.64 1.18e-41 Breast cancer; LIHC cis rs6754311 0.551 rs10928545 chr2:136501840 A/G cg25344623 chr2:136566232 LCT 0.4 7.63 0.38 2.42e-13 Mosquito bite size; LIHC cis rs9733 0.744 rs12126004 chr1:150889877 T/C cg13175981 chr1:150552382 MCL1 0.5 7.03 0.36 1.09e-11 Tonsillectomy; LIHC cis rs933688 1.000 rs12655973 chr5:90736537 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 20.48 0.74 2.02e-61 Smoking behavior; LIHC trans rs7618501 0.966 rs9882639 chr3:49799475 A/C cg21659725 chr3:3221576 CRBN 0.99 19.71 0.73 2.65e-58 Intelligence (multi-trait analysis); LIHC cis rs600806 0.821 rs417270 chr1:109849144 T/C cg23091122 chr1:110024289 SYPL2 -0.45 -5.71 -0.3 2.44e-8 Intelligence (multi-trait analysis); LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 21.74 0.76 1.99e-66 Prudent dietary pattern; LIHC cis rs2303759 0.918 rs1054770 chr19:49878115 G/A cg24324837 chr19:49891574 CCDC155 0.38 6.14 0.31 2.32e-9 Multiple sclerosis; LIHC cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg13770153 chr20:60521292 NA -0.36 -7.17 -0.36 4.78e-12 Body mass index; LIHC cis rs2842992 0.724 rs1128670 chr6:160211636 G/A cg11366901 chr6:160182831 ACAT2 0.86 14.38 0.61 5.22e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs7635838 0.617 rs346074 chr3:11294310 T/C cg00170343 chr3:11313890 ATG7 0.6 9.93 0.47 1.35e-20 HDL cholesterol; LIHC cis rs769267 0.965 rs2315024 chr19:19423817 T/A cg15052019 chr19:19431593 KIAA0892;SF4 0.42 5.89 0.3 9.18e-9 Tonsillectomy; LIHC cis rs2153535 0.580 rs915350 chr6:8443486 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15326801 chr14:94596007 IFI27L2 -0.55 -6.36 -0.33 6.53e-10 Systolic blood pressure; LIHC cis rs4466137 0.953 rs6869030 chr5:83007311 C/T cg16102102 chr5:83017553 HAPLN1 -0.59 -8.74 -0.43 1.09e-16 Prostate cancer; LIHC cis rs10751667 0.600 rs10902264 chr11:1003523 G/A cg10932868 chr11:921992 NA 0.34 6.42 0.33 4.67e-10 Alzheimer's disease (late onset); LIHC cis rs1816752 0.905 rs9511264 chr13:25012217 C/T cg02811702 chr13:24901961 NA -0.25 -6.33 -0.32 7.65e-10 Obesity-related traits; LIHC cis rs503341 0.756 rs612010 chr11:63591005 G/A cg04362095 chr11:63592001 C11orf84 -0.68 -13.73 -0.6 1.85e-34 Pulse pressure; LIHC cis rs317689 0.788 rs317679 chr12:69693172 A/C cg20891283 chr12:69753455 YEATS4 0.58 8.71 0.43 1.29e-16 Response to diuretic therapy; LIHC cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.37 0.33 5.95e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8062405 0.755 rs4788080 chr16:28558081 C/T cg16576597 chr16:28551801 NUPR1 0.49 7.76 0.39 9.79e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg27170947 chr2:26402098 FAM59B 0.66 8.34 0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs929354 0.772 rs10229630 chr7:157004790 C/T cg16102536 chr7:156981717 UBE3C 0.35 5.82 0.3 1.38e-8 Body mass index; LIHC cis rs7020830 0.898 rs12555207 chr9:37315476 C/T cg14294708 chr9:37120828 ZCCHC7 1.03 20.76 0.75 1.6e-62 Schizophrenia; LIHC cis rs2153535 0.541 rs4637688 chr6:8446501 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.5 0.42 6e-16 Motion sickness; LIHC cis rs1005277 0.540 rs7903942 chr10:37929276 C/T cg00409905 chr10:38381863 ZNF37A 0.57 9.83 0.47 3.09e-20 Extrinsic epigenetic age acceleration; LIHC cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg11890956 chr21:40555474 PSMG1 -0.46 -7.43 -0.37 8.54e-13 Cognitive function; LIHC cis rs9581857 0.547 rs9579087 chr13:28059780 G/A cg22138327 chr13:27999177 GTF3A 0.8 6.07 0.31 3.32e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs1728785 1.000 rs1170429 chr16:68604126 A/G cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs6088590 0.931 rs12625149 chr20:33425812 A/C cg24642439 chr20:33292090 TP53INP2 -0.78 -10.85 -0.51 8.75e-24 Coronary artery disease; LIHC cis rs11871801 0.517 rs10454087 chr17:40735641 C/T cg14558262 chr17:40713999 COASY 0.61 9.39 0.45 8.98e-19 Crohn's disease; LIHC cis rs782590 0.935 rs62165197 chr2:55801812 C/T cg18811423 chr2:55921094 PNPT1 0.93 15.16 0.63 4.39e-40 Metabolic syndrome; LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg07157834 chr1:205819609 PM20D1 -0.66 -9.94 -0.47 1.32e-20 Menarche (age at onset); LIHC cis rs35306767 0.903 rs35957139 chr10:884889 C/T cg20503657 chr10:835505 NA 1.35 14.76 0.62 1.75e-38 Eosinophil percentage of granulocytes; LIHC cis rs1005277 0.557 rs2983338 chr10:38550734 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.38 -0.33 5.89e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9733 0.596 rs72700897 chr1:150626038 C/G cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs1865760 0.566 rs9379821 chr6:26054268 A/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.74 0.3 2.1e-8 Height; LIHC cis rs4925386 0.840 rs6143035 chr20:60920700 C/T cg24112000 chr20:60950667 NA 0.47 6.47 0.33 3.45e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs6088590 1.000 rs6120708 chr20:33335526 G/A cg24642439 chr20:33292090 TP53INP2 0.8 11.42 0.53 8.65e-26 Coronary artery disease; LIHC cis rs17106184 0.892 rs111779227 chr1:51328987 A/C cg07174182 chr1:51127561 FAF1 -0.62 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg02990361 chr1:107599529 PRMT6 -0.66 -10.88 -0.51 7.07e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.74 0.39 1.17e-13 Prudent dietary pattern; LIHC trans rs1075232 0.510 rs78884938 chr15:31510885 C/T cg04373760 chr16:53404718 NA 0.69 6.96 0.35 1.79e-11 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs1559088 0.576 rs7251626 chr19:33578470 C/A cg27124370 chr19:33622961 WDR88 0.63 9.29 0.45 1.84e-18 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs11673344 0.764 rs13345491 chr19:37473099 G/T cg27390819 chr19:37464633 NA -0.49 -5.91 -0.3 8.23e-9 Obesity-related traits; LIHC cis rs1784581 0.507 rs1790020 chr6:162366266 C/T cg17173639 chr6:162384350 PARK2 -0.5 -9.0 -0.44 1.59e-17 Itch intensity from mosquito bite; LIHC trans rs7618501 0.540 rs11130241 chr3:50131459 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.59 -9.46 -0.46 5.02e-19 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.966 rs11953833 chr5:140155123 T/A cg19875535 chr5:140030758 IK 0.36 5.83 0.3 1.28e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.3 -6.01 -0.31 4.86e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs910316 0.967 rs4903292 chr14:75656245 A/G cg08847533 chr14:75593920 NEK9 0.78 15.8 0.65 1.3e-42 Height; LIHC cis rs11758351 0.517 rs79958315 chr6:26221826 C/T cg03854865 chr6:26224070 HIST1H3E 0.57 6.42 0.33 4.54e-10 Gout;Renal underexcretion gout; LIHC cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg02187348 chr16:89574699 SPG7 0.52 7.74 0.39 1.15e-13 Multiple myeloma (IgH translocation); LIHC cis rs9814567 1.000 rs55913793 chr3:134285968 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7116495 1.000 rs1541306 chr11:71708013 G/A cg26138937 chr11:71823887 C11orf51 -0.71 -7.3 -0.37 1.97e-12 Severe influenza A (H1N1) infection; LIHC cis rs925946 0.518 rs7107410 chr11:27551388 T/C cg18117895 chr11:27722066 BDNF 0.44 5.72 0.3 2.33e-8 Body mass index;Weight; LIHC cis rs4919694 1.000 rs77505796 chr10:104647774 A/T cg04362960 chr10:104952993 NT5C2 1.09 7.79 0.39 8.36e-14 Arsenic metabolism; LIHC cis rs1046896 0.961 rs7208565 chr17:80696692 C/T cg02711726 chr17:80685570 FN3KRP -0.57 -11.05 -0.51 1.74e-24 Glycated hemoglobin levels; LIHC cis rs8072100 0.840 rs9900360 chr17:45491979 C/T cg08085267 chr17:45401833 C17orf57 -0.55 -8.25 -0.41 3.46e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg16049864 chr8:95962084 TP53INP1 -0.53 -9.29 -0.45 1.86e-18 Type 2 diabetes; LIHC cis rs7107174 0.892 rs2511167 chr11:77964698 C/T cg02023728 chr11:77925099 USP35 0.48 9.03 0.44 1.28e-17 Testicular germ cell tumor; LIHC cis rs2976388 0.609 rs2585140 chr8:143806896 A/G cg06565975 chr8:143823917 SLURP1 0.34 6.69 0.34 8.92e-11 Urinary tract infection frequency; LIHC cis rs2153535 0.580 rs1932275 chr6:8442333 T/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs765787 0.530 rs11854690 chr15:45516016 C/T cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs2576037 0.583 rs8096263 chr18:44515216 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.68 11.05 0.51 1.73e-24 Personality dimensions; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00834988 chr7:70060153 AUTS2 0.36 6.22 0.32 1.44e-9 Cognitive function; LIHC cis rs67311347 0.955 rs6764102 chr3:40378153 C/G cg16822855 chr3:40428330 ENTPD3 0.34 6.1 0.31 2.89e-9 Renal cell carcinoma; LIHC cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs1453562 chr2:99615850 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.72 -0.5 2.62e-23 Chronic sinus infection; LIHC cis rs17539620 0.624 rs871069 chr6:154837578 A/C cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.73 0.39 1.23e-13 Prudent dietary pattern; LIHC cis rs6752107 1.000 rs2289472 chr2:234182240 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.54 0.42 4.46e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs477692 1.000 rs508303 chr10:131424996 A/T cg05714579 chr10:131428358 MGMT -0.43 -6.94 -0.35 1.96e-11 Response to temozolomide; LIHC cis rs11758351 1.000 rs2143346 chr6:26198449 C/G cg03854865 chr6:26224070 HIST1H3E -0.62 -7.09 -0.36 7.5e-12 Gout;Renal underexcretion gout; LIHC cis rs9814567 1.000 rs10804632 chr3:134294501 T/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.39 -5.86 -0.3 1.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1046896 0.739 rs28459016 chr17:80741194 G/A cg22325292 chr17:80708367 FN3K 0.38 6.04 0.31 4.02e-9 Glycated hemoglobin levels; LIHC cis rs10752881 0.875 rs10752894 chr1:183050610 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Colorectal cancer; LIHC cis rs12995491 0.698 rs34352413 chr2:88498754 T/G cg07952391 chr2:88470173 THNSL2 -0.41 -5.73 -0.3 2.26e-8 Response to metformin (IC50); LIHC cis rs807029 0.577 rs7903239 chr10:102758337 G/T cg25179470 chr10:102756915 LZTS2 0.45 6.23 0.32 1.36e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7107174 1.000 rs11237456 chr11:78040780 C/G cg02023728 chr11:77925099 USP35 0.43 8.37 0.41 1.47e-15 Testicular germ cell tumor; LIHC cis rs67311347 0.955 rs4973999 chr3:40460383 G/A cg18306943 chr3:40428807 ENTPD3 0.34 5.92 0.3 7.9e-9 Renal cell carcinoma; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs11871801 0.517 rs34855406 chr17:40731411 G/C cg14558262 chr17:40713999 COASY 0.52 6.82 0.35 4.24e-11 Crohn's disease; LIHC cis rs782590 0.687 rs62165255 chr2:55932585 G/A cg18811423 chr2:55921094 PNPT1 0.88 13.49 0.59 1.56e-33 Metabolic syndrome; LIHC cis rs8180040 0.620 rs9858443 chr3:47086048 G/A cg27129171 chr3:47204927 SETD2 0.56 9.3 0.45 1.7e-18 Colorectal cancer; LIHC cis rs4076764 0.535 rs4409627 chr1:163382050 A/G cg06092702 chr1:163392909 NA 0.19 6.01 0.31 4.74e-9 Motion sickness; LIHC cis rs1008375 0.900 rs12650220 chr4:17595365 A/T cg02297831 chr4:17616191 MED28 0.46 7.08 0.36 7.99e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs6058796 1.000 rs6141781 chr20:31263342 C/T cg02600331 chr11:130417168 NA 0.36 7.86 0.39 4.98e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs16828019 0.852 rs12048187 chr1:41616183 A/G cg03387723 chr1:41708464 SCMH1 -0.45 -7.22 -0.36 3.37e-12 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.800 rs72790306 chr2:24111311 T/G cg08917208 chr2:24149416 ATAD2B 0.94 8.43 0.41 1e-15 Lymphocyte counts; LIHC cis rs6684514 1.000 rs10908494 chr1:156263097 A/G cg16558208 chr1:156270281 VHLL 0.53 10.11 0.48 3.29e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg13976866 chr7:128696069 LOC286016;TNPO3 -0.38 -6.17 -0.32 1.94e-9 Pain; LIHC cis rs1401999 0.898 rs4148561 chr3:183726379 A/G cg01324343 chr3:183735012 ABCC5 0.77 12.66 0.56 2.13e-30 Anterior chamber depth; LIHC cis rs782590 1.000 rs782594 chr2:55844445 T/C cg18811423 chr2:55921094 PNPT1 1.0 15.93 0.65 3.93e-43 Metabolic syndrome; LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg02782426 chr3:40428986 ENTPD3 0.33 6.08 0.31 3.19e-9 Renal cell carcinoma; LIHC cis rs11190604 1.000 rs7070776 chr10:102264672 A/G cg07080220 chr10:102295463 HIF1AN 0.55 8.0 0.4 2.01e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6570726 0.791 rs12208019 chr6:145935572 T/C cg13319975 chr6:146136371 FBXO30 -0.43 -6.74 -0.34 6.68e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs801193 1.000 rs2707854 chr7:66212597 G/A cg18876405 chr7:65276391 NA 0.42 7.32 0.37 1.79e-12 Aortic root size; LIHC trans rs9951602 0.573 rs78623099 chr18:76646228 G/T cg02800362 chr5:177631904 HNRNPAB 0.66 10.47 0.49 1.89e-22 Obesity-related traits; LIHC cis rs6952808 0.609 rs6950151 chr7:1953521 T/C cg03354898 chr7:1950403 MAD1L1 -0.38 -6.07 -0.31 3.49e-9 Bipolar disorder and schizophrenia; LIHC cis rs919433 0.926 rs12618567 chr2:198148191 A/T cg10820045 chr2:198174542 NA -0.59 -9.89 -0.47 1.85e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1008375 0.966 rs6833808 chr4:17652526 T/A cg02297831 chr4:17616191 MED28 0.5 7.8 0.39 7.38e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05400618 chr7:2128721 MAD1L1 0.62 7.5 0.38 5.55e-13 Systolic blood pressure; LIHC cis rs748404 0.560 rs529611 chr15:43805988 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.44 7.39 0.37 1.12e-12 Lung cancer; LIHC cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg09323728 chr8:95962352 TP53INP1 -0.35 -7.77 -0.39 9.19e-14 Type 2 diabetes; LIHC cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs6690583 1.000 rs10443172 chr1:85485768 T/C cg22153463 chr1:85462885 MCOLN2 -0.46 -6.1 -0.31 2.82e-9 Serum sulfate level; LIHC cis rs7959452 0.590 rs11177643 chr12:69785712 T/G cg20891283 chr12:69753455 YEATS4 0.9 19.55 0.73 1.18e-57 Blood protein levels; LIHC trans rs528418 0.651 rs77111222 chr6:145542401 C/G cg09173621 chr13:111773936 ARHGEF7 0.52 6.04 0.31 4.03e-9 Methadone dose in opioid dependence; LIHC cis rs11122272 0.735 rs2790890 chr1:231514567 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.4 0.45 7.89e-19 Hemoglobin concentration; LIHC cis rs12478296 0.685 rs67829386 chr2:242992276 T/A cg18898632 chr2:242989856 NA -0.5 -7.05 -0.36 9.66e-12 Obesity-related traits; LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs4423214 1.000 rs12790010 chr11:71170653 T/C cg05163923 chr11:71159392 DHCR7 0.89 13.62 0.59 4.7e-34 Vitamin D levels; LIHC cis rs7119038 0.818 rs10892279 chr11:118611781 G/A cg19308663 chr11:118741387 NA 0.41 6.31 0.32 8.52e-10 Sjögren's syndrome; LIHC cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg23172400 chr8:95962367 TP53INP1 -0.43 -10.12 -0.48 3.14e-21 Type 2 diabetes; LIHC cis rs651907 0.557 rs11720745 chr3:101441690 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.4 0.49 3.31e-22 Colorectal cancer; LIHC cis rs365132 1.000 rs353493 chr5:176432585 T/C cg16309518 chr5:176445507 NA -0.58 -11.56 -0.53 2.58e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs1538970 1.000 rs17395553 chr1:45864761 C/T cg05343316 chr1:45956843 TESK2 0.57 8.51 0.42 5.67e-16 Platelet count; LIHC cis rs910316 0.874 rs61980828 chr14:75630378 G/A cg08847533 chr14:75593920 NEK9 -0.87 -18.9 -0.71 4.62e-55 Height; LIHC cis rs730775 0.505 rs324137 chr6:44273546 G/T cg21130236 chr6:44246755 TMEM151B 0.23 6.6 0.34 1.53e-10 Monocyte percentage of white cells;Monocyte count; LIHC cis rs7618501 1.000 rs4855867 chr3:49745822 C/T cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.559 rs72796103 chr2:23900382 G/A cg08917208 chr2:24149416 ATAD2B 0.98 8.06 0.4 1.29e-14 Lymphocyte counts; LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.96e-16 Prudent dietary pattern; LIHC trans rs1814175 0.817 rs2866863 chr11:49953242 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.14 -0.78 6.05e-72 Height; LIHC trans rs3858145 0.588 rs61854837 chr10:70042370 C/G cg04882175 chr6:131122610 NA -0.5 -6.22 -0.32 1.48e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg21724239 chr8:58056113 NA 0.57 7.11 0.36 6.9e-12 Developmental language disorder (linguistic errors); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg02505535 chr3:195703920 SDHAP1 0.35 6.39 0.33 5.45e-10 Longevity; LIHC cis rs7493 0.755 rs34774523 chr7:94962142 G/A cg19678392 chr7:94953810 PON1 -0.45 -5.9 -0.3 8.71e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs9381040 0.610 rs2057002 chr6:41022962 G/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.86 -0.3 1.09e-8 Alzheimer's disease (late onset); LIHC cis rs7572733 0.534 rs1464209 chr2:198814396 A/G cg10820045 chr2:198174542 NA 0.48 7.28 0.37 2.36e-12 Dermatomyositis; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg06972615 chr5:77081292 NA 0.51 6.78 0.34 5.23e-11 Lung function (FEV1); LIHC trans rs3780486 0.846 rs73484568 chr9:33132492 G/A cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs11031096 0.782 rs2165728 chr11:4147004 T/C cg18678763 chr11:4115507 RRM1 -0.53 -8.12 -0.4 8.34e-15 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.22 0.55 9.92e-29 Prudent dietary pattern; LIHC cis rs35306767 0.714 rs10508206 chr10:1075777 A/C cg26597838 chr10:835615 NA 0.64 7.18 0.36 4.25e-12 Eosinophil percentage of granulocytes; LIHC cis rs6754311 0.550 rs12994270 chr2:136518103 T/A cg07305463 chr2:136567211 LCT 0.4 7.34 0.37 1.57e-12 Mosquito bite size; LIHC cis rs765787 0.530 rs4775836 chr15:45537664 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs62179067 0.708 rs16866624 chr2:179936770 C/G cg07532576 chr2:179544947 TTN 0.58 5.73 0.3 2.18e-8 Late-onset Alzheimer's disease; LIHC cis rs7044106 0.762 rs12003646 chr9:123470621 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 8.06 0.4 1.32e-14 Hip circumference adjusted for BMI; LIHC cis rs9640161 0.789 rs2373751 chr7:150021599 G/C cg17279839 chr7:150038598 RARRES2 0.58 11.74 0.54 5.48e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs2576037 0.526 rs10853547 chr18:44530548 A/C cg19077165 chr18:44547161 KATNAL2 -0.43 -6.48 -0.33 3.2e-10 Personality dimensions; LIHC cis rs861318 0.702 rs3018316 chr1:159017958 G/T cg11003133 chr1:159046391 AIM2 0.32 6.21 0.32 1.51e-9 Obesity-related traits; LIHC cis rs9399135 0.967 rs9376077 chr6:135299713 C/G cg22676075 chr6:135203613 NA 0.39 6.28 0.32 1.04e-9 Red blood cell count; LIHC cis rs9372498 0.505 rs1690655 chr6:118653045 A/T cg01339444 chr6:118972232 C6orf204 0.71 6.24 0.32 1.26e-9 Diastolic blood pressure; LIHC cis rs2439831 0.850 rs7179388 chr15:44123945 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.57 6.95 0.35 1.88e-11 Lung cancer in ever smokers; LIHC cis rs7818688 0.697 rs58314911 chr8:95985111 G/A cg16049864 chr8:95962084 TP53INP1 0.6 6.51 0.33 2.69e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7552404 0.727 rs5745433 chr1:76333163 T/G cg10523679 chr1:76189770 ACADM 0.57 7.17 0.36 4.75e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs35110281 0.715 rs969060 chr21:45080852 T/G cg01579765 chr21:45077557 HSF2BP -0.36 -6.57 -0.33 1.92e-10 Mean corpuscular volume; LIHC cis rs941873 0.772 rs7086293 chr10:81103247 T/C cg09469691 chr10:81107165 PPIF 0.68 10.45 0.49 2.29e-22 Height; LIHC cis rs4819052 0.851 rs8126930 chr21:46671715 A/G cg11663144 chr21:46675770 NA -0.32 -6.1 -0.31 2.94e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs477895 0.713 rs11600867 chr11:63972052 T/A cg04317338 chr11:64019027 PLCB3 0.81 9.71 0.46 7.72e-20 Mean platelet volume; LIHC cis rs1008375 1.000 rs28501187 chr4:17643620 G/A cg16339924 chr4:17578868 LAP3 0.44 6.08 0.31 3.19e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9929218 0.953 rs16260 chr16:68771034 C/A cg01231543 chr16:68741748 NA 0.39 6.28 0.32 1.05e-9 Colorectal cancer; LIHC cis rs1113500 0.933 rs11185250 chr1:108616417 A/G cg06207961 chr1:108661230 NA 0.37 7.29 0.37 2.1e-12 Growth-regulated protein alpha levels; LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg07677032 chr17:61819896 STRADA 0.43 6.31 0.32 8.5e-10 Prudent dietary pattern; LIHC cis rs17666538 0.585 rs1669615 chr8:616665 T/C cg07234876 chr8:600039 NA 0.91 7.14 0.36 5.67e-12 IgG glycosylation; LIHC cis rs2242116 0.796 rs4683296 chr3:46973820 G/C cg02527881 chr3:46936655 PTH1R 0.45 9.1 0.44 7.49e-18 Birth weight; LIHC cis rs365132 0.875 rs2454952 chr5:176376493 C/T cg16309518 chr5:176445507 NA -0.53 -10.05 -0.48 5.22e-21 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs8056893 0.686 rs3826167 chr16:68397530 T/G cg02226672 chr16:68398533 SMPD3 0.43 6.06 0.31 3.58e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.55 -0.38 4.11e-13 Initial pursuit acceleration; LIHC cis rs6840360 0.530 rs62327350 chr4:152641202 G/A cg22705602 chr4:152727874 NA -0.4 -7.39 -0.37 1.15e-12 Intelligence (multi-trait analysis); LIHC cis rs2066819 1.000 rs871130 chr12:56648777 A/G cg26714650 chr12:56694279 CS 1.29 12.34 0.55 3.55e-29 Psoriasis vulgaris; LIHC cis rs7107174 1.000 rs901103 chr11:77931346 C/T cg02023728 chr11:77925099 USP35 0.51 9.49 0.46 4.15e-19 Testicular germ cell tumor; LIHC cis rs4930103 0.935 rs2071095 chr11:2020627 C/A cg06197492 chr11:2016605 H19 0.37 5.86 0.3 1.11e-8 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs9303401 0.659 rs61291849 chr17:56909867 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.19 0.58 2.13e-32 Cognitive test performance; LIHC cis rs74233809 1.000 rs12219901 chr10:104840967 A/G cg03493300 chr10:104813866 CNNM2 0.48 6.4 0.33 5.23e-10 Birth weight; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.12 0.4 8.4e-15 Height; LIHC cis rs5753037 0.547 rs140134 chr22:30163332 G/A cg01021169 chr22:30184971 ASCC2 -0.41 -7.99 -0.4 2.08e-14 Type 1 diabetes; LIHC cis rs4699052 0.927 rs1870888 chr4:104169326 G/C cg16532752 chr4:104119610 CENPE -0.39 -6.24 -0.32 1.31e-9 Testicular germ cell tumor; LIHC cis rs875971 0.545 rs17138156 chr7:65714695 C/T cg11764359 chr7:65958608 NA 0.52 7.2 0.36 3.82e-12 Aortic root size; LIHC cis rs6942756 0.956 rs13235668 chr7:128879710 A/G cg02491457 chr7:128862824 NA -0.73 -11.49 -0.53 4.78e-26 White matter hyperintensity burden; LIHC cis rs9733 0.791 rs11800059 chr1:150651175 C/T cg18016565 chr1:150552671 MCL1 -0.5 -10.34 -0.49 5.31e-22 Tonsillectomy; LIHC cis rs909341 0.818 rs6122154 chr20:62359345 C/T cg03999872 chr20:62272968 STMN3 -0.45 -6.78 -0.34 5.24e-11 Atopic dermatitis; LIHC trans rs7615952 0.558 rs17334039 chr3:125540308 A/G cg07211511 chr3:129823064 LOC729375 -0.49 -7.6 -0.38 2.86e-13 Blood pressure (smoking interaction); LIHC cis rs1348850 0.793 rs12990917 chr2:178487259 T/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.67 9.32 0.45 1.52e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs66887589 0.775 rs6843229 chr4:120424087 T/C cg25214090 chr10:38739885 LOC399744 0.38 6.27 0.32 1.09e-9 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11595794 chr4:186317094 ANKRD37 0.45 6.3 0.32 9.17e-10 Pancreatic cancer; LIHC cis rs10504229 0.871 rs56372514 chr8:58157166 A/G cg02290350 chr8:58132656 NA 0.37 7.99 0.4 2.13e-14 Developmental language disorder (linguistic errors); LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg10546562 chr7:5390491 TNRC18 0.51 7.07 0.36 9.02e-12 Hip circumference; LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg07781247 chr5:93954443 ANKRD32;C5orf36 0.42 6.25 0.32 1.2e-9 Gut microbiome composition (summer); LIHC cis rs910316 1.000 rs175443 chr14:75601963 C/T cg11812906 chr14:75593930 NEK9 -0.75 -14.96 -0.63 2.78e-39 Height; LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg02951883 chr7:2050386 MAD1L1 0.77 13.94 0.6 2.81e-35 Bipolar disorder and schizophrenia; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg07175572 chr10:89310145 MINPP1 -0.29 -6.37 -0.33 6.28e-10 Calcium levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg12716232 chr8:43001931 HGSNAT -0.32 -6.31 -0.32 8.54e-10 Calcium levels; LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs8177179 0.967 rs9869311 chr3:133451613 C/T cg18769074 chr3:133464867 TF 0.27 6.09 0.31 3.02e-9 Iron status biomarkers (transferrin levels); LIHC cis rs55665837 0.540 rs4144487 chr11:14750451 C/G cg19336497 chr11:14380999 RRAS2 -0.34 -5.74 -0.3 2.13e-8 Vitamin D levels; LIHC cis rs35110281 0.744 rs162395 chr21:44945759 T/C cg04455712 chr21:45112962 RRP1B 0.43 7.1 0.36 7.45e-12 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg11764359 chr7:65958608 NA 0.58 6.03 0.31 4.29e-9 Diabetic kidney disease; LIHC cis rs1568889 1.000 rs61889054 chr11:28333000 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.53 0.33 2.44e-10 Bipolar disorder; LIHC cis rs1707322 0.721 rs10890343 chr1:46157922 C/T cg03146154 chr1:46216737 IPP 0.59 10.23 0.48 1.37e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12497850 0.931 rs1134591 chr3:48972892 C/T cg06212747 chr3:49208901 KLHDC8B 0.56 7.34 0.37 1.53e-12 Parkinson's disease; LIHC cis rs1403694 0.695 rs5029975 chr3:186436918 A/G cg12454167 chr3:186435060 KNG1 -0.37 -8.56 -0.42 3.93e-16 Blood protein levels; LIHC cis rs4925386 0.840 rs6143036 chr20:60921721 C/A cg06026331 chr20:60912101 LAMA5 0.65 9.6 0.46 1.74e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs16944613 0.541 rs4566137 chr15:91097964 A/G cg26821196 chr15:91095069 CRTC3 0.51 8.78 0.43 7.94e-17 Colorectal cancer; LIHC cis rs36051895 0.664 rs11793659 chr9:5109707 A/G cg02405213 chr9:5042618 JAK2 -0.64 -10.73 -0.5 2.44e-23 Pediatric autoimmune diseases; LIHC cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg06481639 chr22:41940642 POLR3H -0.69 -7.04 -0.36 1.08e-11 Vitiligo; LIHC cis rs1904096 0.506 rs13435702 chr4:95167751 G/A cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.12 -0.44 6.35e-18 Type 2 diabetes; LIHC cis rs6964587 1.000 rs56072181 chr7:91690457 A/G cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs6089584 0.566 rs7274240 chr20:60622004 C/T cg06108461 chr20:60628389 TAF4 -0.64 -9.04 -0.44 1.23e-17 Body mass index; LIHC cis rs2180341 0.883 rs9388568 chr6:127690694 C/A cg27446573 chr6:127587934 RNF146 1.0 15.51 0.64 1.82e-41 Breast cancer; LIHC cis rs1568889 0.938 rs1464898 chr11:28034748 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.07 0.36 8.51e-12 Bipolar disorder; LIHC cis rs9549367 0.789 rs7317558 chr13:113893625 G/A cg18105134 chr13:113819100 PROZ -0.58 -10.29 -0.49 8e-22 Platelet distribution width; LIHC cis rs9399137 0.507 rs13209780 chr6:135344795 G/C cg24558204 chr6:135376177 HBS1L 0.63 10.78 0.5 1.63e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs6835098 0.608 rs2332668 chr4:174163360 A/G cg27433088 chr4:174089019 GALNT7 0.33 5.77 0.3 1.76e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg03843852 chr15:55611099 PIGB -0.57 -6.16 -0.32 2.05e-9 Bronchial neuroendocrine tumor; LIHC cis rs41271473 0.526 rs12143098 chr1:228720965 A/C cg10167378 chr1:228756711 NA 0.67 6.77 0.34 5.65e-11 Chronic lymphocytic leukemia; LIHC cis rs2629751 0.512 rs2583271 chr12:104440855 C/T cg14987745 chr12:104360022 TDG -0.66 -6.38 -0.33 5.81e-10 Hepatitis C induced liver fibrosis; LIHC cis rs7551222 0.752 rs2290854 chr1:204516025 A/G cg20240347 chr1:204465584 NA -0.36 -7.68 -0.38 1.68e-13 Schizophrenia; LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg04234412 chr22:24373322 LOC391322 -0.73 -11.14 -0.52 8.78e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1538970 0.924 rs3790582 chr1:45887288 T/C cg24296786 chr1:45957014 TESK2 -0.49 -7.13 -0.36 6.04e-12 Platelet count; LIHC cis rs67311347 0.869 rs6790495 chr3:40366770 C/T cg16822855 chr3:40428330 ENTPD3 0.34 6.12 0.31 2.56e-9 Renal cell carcinoma; LIHC cis rs151997 0.671 rs152099 chr5:50210091 A/G cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC cis rs10426930 0.816 rs2602728 chr19:5046318 C/T cg18473234 chr19:5097819 KDM4B 0.53 6.72 0.34 7.64e-11 Monocyte percentage of white cells; LIHC cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7086627 0.515 rs11202960 chr10:82209807 G/A cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC cis rs10193935 0.892 rs6744964 chr2:42441088 A/G cg27598129 chr2:42591480 NA -0.74 -11.35 -0.52 1.46e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs6061231 0.546 rs482220 chr20:60927482 G/A cg24112000 chr20:60950667 NA 0.48 7.41 0.37 1.01e-12 Colorectal cancer; LIHC cis rs2251381 0.606 rs8129515 chr21:30520167 C/G cg24692254 chr21:30365293 RNF160 0.72 10.74 0.5 2.22e-23 Selective IgA deficiency; LIHC cis rs7149337 1.000 rs35567150 chr14:51725944 A/G cg23942311 chr14:51606299 NA 0.34 6.54 0.33 2.26e-10 Cancer; LIHC cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.46 7.37 0.37 1.33e-12 Bipolar disorder; LIHC cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg19723775 chr5:179050963 HNRNPH1 -0.45 -7.03 -0.36 1.12e-11 Lung cancer; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25629694 chr17:62657497 SMURF2 -0.45 -6.52 -0.33 2.54e-10 Bilirubin levels; LIHC cis rs17253792 0.822 rs78988988 chr14:56152404 G/A cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC trans rs4650994 0.525 rs4457535 chr1:178497186 C/T cg05059571 chr16:84539110 KIAA1609 0.42 7.1 0.36 7.42e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2072499 0.695 rs112223391 chr1:156156094 G/A cg25208724 chr1:156163844 SLC25A44 0.72 8.22 0.41 4.29e-15 Testicular germ cell tumor; LIHC cis rs2997447 0.761 rs17257107 chr1:26448447 A/G cg19633962 chr1:26362018 EXTL1 -0.64 -5.88 -0.3 9.64e-9 QRS complex (12-leadsum); LIHC cis rs2839186 0.721 rs13051200 chr21:47701693 A/T cg05896524 chr21:47604654 C21orf56 0.44 6.64 0.34 1.25e-10 Testicular germ cell tumor; LIHC trans rs7618501 0.633 rs4688757 chr3:50035323 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.54 0.46 2.89e-19 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.935 rs3742668 chr14:90767759 G/A cg04374321 chr14:90722782 PSMC1 -0.77 -14.81 -0.63 1.08e-38 Mortality in heart failure; LIHC cis rs3749237 0.555 rs2117939 chr3:49415179 C/A cg03060546 chr3:49711283 APEH 0.58 9.48 0.46 4.31e-19 Resting heart rate; LIHC cis rs7762018 1.000 rs6912959 chr6:170126224 G/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.54 6.24 0.32 1.3e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs877282 0.838 rs11253374 chr10:774961 C/T cg22713356 chr15:30763199 NA 1.32 11.94 0.54 1.03e-27 Uric acid levels; LIHC cis rs9916302 0.861 rs11078896 chr17:37415544 C/T cg07936489 chr17:37558343 FBXL20 -0.84 -13.62 -0.59 4.57e-34 Glomerular filtration rate (creatinine); LIHC cis rs7662987 0.517 rs3018048 chr4:100005538 C/T cg13256891 chr4:100009986 ADH5 0.59 5.92 0.3 7.98e-9 Smoking initiation; LIHC cis rs13177718 0.908 rs7713158 chr5:108179300 G/A cg20423064 chr5:108166851 FER -0.59 -6.46 -0.33 3.59e-10 Height; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03047724 chr7:139477895 TBXAS1;HIPK2 0.42 6.39 0.33 5.34e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg03517284 chr6:25882590 NA -0.65 -8.27 -0.41 3.07e-15 Intelligence (multi-trait analysis); LIHC cis rs7584330 0.554 rs74832280 chr2:238426625 G/A cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.25e-12 Bipolar disorder; LIHC cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg18252515 chr7:66147081 NA -1.29 -16.99 -0.68 2.36e-47 Diabetic kidney disease; LIHC cis rs72781680 0.611 rs36052574 chr2:24306587 A/C cg06627628 chr2:24431161 ITSN2 -0.65 -7.54 -0.38 4.39e-13 Lymphocyte counts; LIHC cis rs3806843 0.900 rs3756334 chr5:140213796 G/A cg26395211 chr5:140044315 WDR55 -0.41 -5.93 -0.31 7.45e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs116095464 0.558 rs6962 chr5:256509 G/A cg22496380 chr5:211416 CCDC127 -1.04 -9.77 -0.47 4.91e-20 Breast cancer; LIHC cis rs8180040 0.764 rs11130115 chr3:47181661 C/A cg02527881 chr3:46936655 PTH1R -0.32 -6.33 -0.32 7.83e-10 Colorectal cancer; LIHC cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg18402987 chr7:1209562 NA 0.77 5.85 0.3 1.17e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs875971 1.000 rs778699 chr7:65868290 G/A cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.46 7.37 0.37 1.26e-12 Bipolar disorder; LIHC cis rs3099143 1.000 rs3102712 chr15:77058926 G/A cg21673338 chr15:77095150 SCAPER -0.5 -7.42 -0.37 9.3e-13 Recalcitrant atopic dermatitis; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg03874509 chr1:107600012 PRMT6 0.77 12.67 0.57 1.91e-30 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10256972 0.640 rs10271082 chr7:1081562 G/C cg23978390 chr7:1156363 C7orf50 0.46 6.62 0.34 1.36e-10 Longevity;Endometriosis; LIHC cis rs9911578 1.000 rs302848 chr17:56686454 C/T cg12560992 chr17:57184187 TRIM37 0.97 18.22 0.7 2.54e-52 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.966 rs4858868 chr3:47455086 G/A cg16586182 chr3:47516702 SCAP -0.58 -11.19 -0.52 5.73e-25 Colorectal cancer; LIHC cis rs1878931 0.624 rs39728 chr16:3453076 A/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.8 13.08 0.58 5.65e-32 Body mass index (adult); LIHC cis rs17685 0.753 rs10085567 chr7:75734206 A/C cg16684958 chr7:75615977 POR 0.51 8.49 0.42 6.26e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8005677 1.000 rs8005677 chr14:23376678 T/C cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 3.07e-9 Cognitive ability (multi-trait analysis); LIHC cis rs611744 0.967 rs597649 chr8:109187718 T/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs1814175 0.645 rs1721996 chr11:49915527 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs4407350 0.870 rs4823327 chr22:44908708 T/C cg11695653 chr22:44894386 LDOC1L -0.35 -6.02 -0.31 4.52e-9 Intelligence (multi-trait analysis); LIHC cis rs922107 0.738 rs12140018 chr1:90025689 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.75 -0.39 1.05e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs703842 0.616 rs7489290 chr12:58228588 C/G cg18357645 chr12:58087776 OS9 -0.4 -5.97 -0.31 5.88e-9 Multiple sclerosis; LIHC cis rs7264396 0.513 rs3787169 chr20:34419884 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -7.94 -0.39 2.92e-14 Total cholesterol levels; LIHC cis rs6732160 0.574 rs7557055 chr2:73472670 G/A cg24220031 chr2:73402428 NA -0.28 -6.0 -0.31 5.16e-9 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09820084 chr6:18387507 RNF144B 0.47 7.22 0.36 3.5e-12 Pancreatic cancer; LIHC cis rs4642101 0.694 rs12631514 chr3:12838293 G/C cg24848339 chr3:12840334 CAND2 0.32 6.32 0.32 8.04e-10 QRS complex (12-leadsum); LIHC cis rs35110281 0.782 rs2051407 chr21:45079245 T/C cg01579765 chr21:45077557 HSF2BP -0.35 -6.55 -0.33 2.14e-10 Mean corpuscular volume; LIHC trans rs2727020 0.894 rs1917328 chr11:49359606 G/A cg18944383 chr4:111397179 ENPEP 0.28 6.42 0.33 4.47e-10 Coronary artery disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13674483 chr17:37212827 NA -0.39 -6.82 -0.35 4.26e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg14393609 chr7:65229607 NA 0.45 6.59 0.34 1.63e-10 Aortic root size; LIHC cis rs916888 0.773 rs199445 chr17:44817408 C/T cg01570182 chr17:44337453 NA 1.01 10.14 0.48 2.67e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7592578 0.679 rs59929070 chr2:191327852 A/G cg27211696 chr2:191398769 TMEM194B -0.54 -6.98 -0.35 1.53e-11 Diastolic blood pressure; LIHC cis rs9902453 1.000 rs9906340 chr17:28398977 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.68 -11.42 -0.53 8.29e-26 Coffee consumption (cups per day); LIHC trans rs9914544 0.564 rs11868520 chr17:18770367 A/G cg21372672 chr17:16614065 CCDC144A -0.28 -6.73 -0.34 7.38e-11 Educational attainment (years of education); LIHC cis rs2404602 0.583 rs2176623 chr15:76568579 C/T cg23625390 chr15:77176239 SCAPER 0.33 5.73 0.3 2.24e-8 Blood metabolite levels; LIHC cis rs7833790 0.724 rs72603871 chr8:82754460 C/G cg02079420 chr8:82753780 SNX16 -0.36 -6.59 -0.34 1.69e-10 Diastolic blood pressure; LIHC cis rs10503871 0.545 rs7822088 chr8:30498193 G/A cg26383811 chr8:30366931 RBPMS 0.42 6.41 0.33 4.72e-10 Metabolite levels (X-11787); LIHC cis rs5758511 0.680 rs5751243 chr22:42617177 T/C cg20195005 chr22:42527684 CYP2D6 0.32 6.01 0.31 4.68e-9 Birth weight; LIHC cis rs4407350 0.870 rs131172 chr22:44902759 A/G cg26276947 chr22:44892394 LDOC1L 0.34 6.62 0.34 1.39e-10 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.692 rs2742470 chr11:9004002 C/T cg12365402 chr11:9010492 NRIP3 -0.29 -7.8 -0.39 7.62e-14 Hemoglobin concentration; LIHC cis rs2439831 0.850 rs28504496 chr15:44016883 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.35 0.41 1.67e-15 Lung cancer in ever smokers; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12832228 chr8:28244096 ZNF395 0.47 6.13 0.31 2.44e-9 Lung function (FEV1/FVC); LIHC cis rs7223966 1.000 rs6504171 chr17:61710010 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.23 0.36 3.16e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2204008 0.807 rs8186948 chr12:38325101 C/G cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.47e-14 Bladder cancer; LIHC cis rs1816752 0.774 rs7986162 chr13:25000079 C/T cg22771759 chr13:24902376 NA 0.32 6.64 0.34 1.22e-10 Obesity-related traits; LIHC cis rs2952156 0.684 rs881844 chr17:37810218 C/G cg07936489 chr17:37558343 FBXL20 -0.44 -6.71 -0.34 8.26e-11 Asthma; LIHC cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg05555928 chr11:63887634 MACROD1 0.55 7.47 0.37 6.77e-13 Mean platelet volume; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg15604507 chr11:19263433 E2F8 0.44 6.05 0.31 3.86e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg16606324 chr3:10149918 C3orf24 0.55 5.94 0.31 6.94e-9 Alzheimer's disease; LIHC cis rs7780883 1.000 rs6946471 chr7:77062284 G/A cg12876866 chr7:77025528 PION -0.45 -5.71 -0.3 2.46e-8 Cervical cancer; LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg24693881 chr1:107596107 NA -0.55 -9.68 -0.46 9.49e-20 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs634534 0.563 rs470192 chr11:65724291 C/T cg17712092 chr4:129076599 LARP1B 0.74 13.04 0.58 8.06e-32 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs10744422 0.858 rs10773627 chr12:123311853 A/G cg22842854 chr12:123319900 HIP1R -0.64 -8.39 -0.41 1.26e-15 Schizophrenia; LIHC cis rs6952808 0.771 rs10244946 chr7:1921068 A/G cg04267008 chr7:1944627 MAD1L1 0.63 10.06 0.48 4.84e-21 Bipolar disorder and schizophrenia; LIHC trans rs875971 0.964 rs778708 chr7:65856319 T/C cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs17685 0.712 rs6954569 chr7:75738885 T/A cg04610667 chr7:75704037 NA -0.33 -6.0 -0.31 5.08e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6542838 0.641 rs4850890 chr2:99535426 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.46 -6.49 -0.33 3.08e-10 Fear of minor pain; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.65 9.4 0.45 7.99e-19 Lymphocyte counts; LIHC trans rs6489882 0.836 rs12322160 chr12:113368505 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs12549902 0.871 rs4736819 chr8:41509915 C/T cg21772509 chr8:41503840 NKX6-3 0.41 6.64 0.34 1.22e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs2370759 1.000 rs11597888 chr10:32635834 G/A cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs9399135 0.869 rs9402675 chr6:135325794 C/G cg24558204 chr6:135376177 HBS1L 0.41 6.71 0.34 8.11e-11 Red blood cell count; LIHC cis rs11958404 0.932 rs7711898 chr5:157430688 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs700651 0.752 rs7592556 chr2:198891021 G/A cg00792783 chr2:198669748 PLCL1 0.43 6.26 0.32 1.15e-9 Intracranial aneurysm; LIHC cis rs7772486 0.727 rs11155442 chr6:146140725 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.97 0.31 5.99e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17539620 0.624 rs62432736 chr6:154834401 A/G cg17771515 chr6:154831774 CNKSR3 0.58 6.19 0.32 1.77e-9 Lipoprotein (a) levels; LIHC cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg13393036 chr8:95962371 TP53INP1 -0.46 -11.04 -0.51 1.87e-24 Type 2 diabetes; LIHC cis rs561341 0.714 rs473535 chr17:30312365 A/G cg00745463 chr17:30367425 LRRC37B -0.79 -5.89 -0.3 9.09e-9 Hip circumference adjusted for BMI; LIHC cis rs595982 0.517 rs10404905 chr19:49406175 A/T cg21252483 chr19:49399788 TULP2 0.57 8.97 0.44 1.96e-17 Red cell distribution width; LIHC cis rs6120849 0.754 rs6088682 chr20:33615702 A/C cg24642439 chr20:33292090 TP53INP2 0.65 7.0 0.35 1.36e-11 Protein C levels; LIHC cis rs11792861 0.926 rs77567374 chr9:111835034 T/C cg13535736 chr9:111863775 C9orf5 -0.39 -5.94 -0.31 7.12e-9 Menarche (age at onset); LIHC cis rs6964587 0.626 rs68009402 chr7:91516226 G/A cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.22e-24 Breast cancer; LIHC cis rs8067545 0.641 rs1479129 chr17:19845769 A/G cg13482628 chr17:19912719 NA 0.4 6.68 0.34 9.93e-11 Schizophrenia; LIHC cis rs6952808 0.929 rs2280548 chr7:1976667 G/T cg14004847 chr7:1930337 MAD1L1 -0.43 -6.19 -0.32 1.74e-9 Bipolar disorder and schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02900441 chr1:15911134 AGMAT -0.52 -6.17 -0.32 1.89e-9 Systolic blood pressure; LIHC cis rs2236918 0.687 rs851778 chr1:242037110 A/G cg17736920 chr1:242011382 EXO1 0.41 5.95 0.31 6.51e-9 Menopause (age at onset); LIHC cis rs6938 0.618 rs2044157 chr15:75225808 G/C cg14664628 chr15:75095509 CSK -0.49 -6.11 -0.31 2.72e-9 Breast cancer; LIHC cis rs6424115 0.964 rs2473375 chr1:24136545 C/T cg15997130 chr1:24165203 NA 0.47 9.54 0.46 2.7e-19 Immature fraction of reticulocytes; LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg09455208 chr3:40491958 NA 0.42 8.46 0.42 7.64e-16 Renal cell carcinoma; LIHC cis rs9858542 0.953 rs9859556 chr3:49455986 G/T cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs11122272 0.735 rs2749707 chr1:231527316 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.2e-18 Hemoglobin concentration; LIHC cis rs240764 0.782 rs12216199 chr6:101152723 C/A cg09795085 chr6:101329169 ASCC3 -0.53 -7.38 -0.37 1.24e-12 Neuroticism; LIHC cis rs11098499 0.569 rs55845118 chr4:120290913 T/C cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC trans rs2243480 1.000 rs67728539 chr7:65378124 G/A cg10756647 chr7:56101905 PSPH 1.09 13.49 0.59 1.56e-33 Diabetic kidney disease; LIHC cis rs4478037 0.822 rs3924696 chr3:33122013 T/C cg27203090 chr3:33138513 GLB1;TMPPE -0.52 -6.51 -0.33 2.6e-10 Major depressive disorder; LIHC cis rs1707322 1.000 rs6676982 chr1:46275401 A/T cg03146154 chr1:46216737 IPP 0.47 7.69 0.38 1.54e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1461503 0.534 rs7123283 chr11:122809055 C/T cg25161029 chr11:122845972 NA 0.34 5.81 0.3 1.4e-8 Menarche (age at onset); LIHC cis rs74181299 0.571 rs12990465 chr2:65281401 C/T cg05010058 chr2:65284262 CEP68 0.37 5.88 0.3 9.76e-9 Pulse pressure; LIHC cis rs17152411 1.000 rs12569940 chr10:126592684 T/C cg07906193 chr10:126599966 NA 0.47 7.25 0.37 2.75e-12 Height; LIHC cis rs9814567 1.000 rs6765505 chr3:134208132 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.51 -0.56 8.09e-30 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4141404 0.923 rs2413035 chr22:31600460 A/G cg07713946 chr22:31675144 LIMK2 -0.4 -6.96 -0.35 1.74e-11 Paclitaxel-induced neuropathy; LIHC cis rs8180040 0.764 rs62246375 chr3:47014464 G/A cg27129171 chr3:47204927 SETD2 -0.62 -10.77 -0.5 1.74e-23 Colorectal cancer; LIHC cis rs4819052 0.565 rs35776291 chr21:46706142 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.86 0.39 5.18e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7772486 0.712 rs6570726 chr6:146159460 T/C cg23711669 chr6:146136114 FBXO30 0.53 9.39 0.45 8.69e-19 Lobe attachment (rater-scored or self-reported); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14579516 chr2:135677120 CCNT2 -0.42 -6.27 -0.32 1.11e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs875971 0.543 rs801191 chr7:66032955 G/A cg26939375 chr7:64535504 NA -0.44 -7.46 -0.37 7.43e-13 Aortic root size; LIHC cis rs79387448 0.745 rs723292 chr2:103166804 A/G cg09003973 chr2:102972529 NA 0.88 7.77 0.39 9.15e-14 Gut microbiota (bacterial taxa); LIHC cis rs765787 0.530 rs7167389 chr15:45535683 A/G cg25801113 chr15:45476975 SHF 0.37 6.28 0.32 1.05e-9 Uric acid levels; LIHC trans rs1005277 0.505 rs719569 chr10:38154415 T/G cg17830980 chr10:43048298 ZNF37B 0.46 8.85 0.43 4.66e-17 Extrinsic epigenetic age acceleration; LIHC cis rs10464366 0.544 rs34866559 chr7:39166071 G/A cg10621924 chr7:39171070 POU6F2 0.42 6.51 0.33 2.67e-10 IgG glycosylation; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg05874655 chr5:40798723 PRKAA1 -0.44 -6.56 -0.33 1.99e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg22903471 chr2:27725779 GCKR -0.53 -9.46 -0.46 4.94e-19 Total body bone mineral density; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg02782426 chr3:40428986 ENTPD3 0.33 6.04 0.31 4.03e-9 Renal cell carcinoma; LIHC cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg15691649 chr6:25882328 NA 0.48 6.67 0.34 1.03e-10 Blood metabolite levels; LIHC cis rs5167 0.506 rs35193317 chr19:45470344 C/T cg09555818 chr19:45449301 APOC2 -0.23 -6.59 -0.34 1.7e-10 Blood protein levels; LIHC cis rs17401966 0.898 rs11582123 chr1:10303942 A/T cg19773385 chr1:10388646 KIF1B -0.39 -7.0 -0.35 1.34e-11 Hepatocellular carcinoma; LIHC cis rs763014 0.932 rs35067229 chr16:649638 T/C cg09256448 chr16:638327 NA 0.39 6.82 0.35 4.1e-11 Height; LIHC cis rs875971 0.862 rs2901152 chr7:65765004 G/A cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs9818758 0.607 rs13087930 chr3:48961726 A/G cg07636037 chr3:49044803 WDR6 -0.79 -7.76 -0.39 9.98e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9303401 0.659 rs34170300 chr17:56789905 G/C cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs7520050 0.966 rs785489 chr1:46576390 A/G cg03146154 chr1:46216737 IPP -0.37 -6.16 -0.32 1.99e-9 Red blood cell count;Reticulocyte count; LIHC cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg19318889 chr4:1322082 MAEA 0.63 10.03 0.48 6.2e-21 Longevity; LIHC cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg25072359 chr17:41440525 NA 0.37 5.84 0.3 1.21e-8 Menopause (age at onset); LIHC cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.48 0.56 1.07e-29 Alzheimer's disease; LIHC cis rs965469 0.895 rs6051843 chr20:3400538 A/G cg25506879 chr20:3388711 C20orf194 -0.53 -6.21 -0.32 1.51e-9 IFN-related cytopenia; LIHC cis rs66782572 1 rs66782572 chr3:52567617 A/G cg18404041 chr3:52824283 ITIH1 -0.43 -7.1 -0.36 7.11e-12 Hemoglobin concentration; LIHC cis rs11577318 0.853 rs4450008 chr1:26643860 C/A cg00852783 chr1:26633632 UBXN11 0.42 6.76 0.34 6.12e-11 Granulocyte percentage of myeloid white cells; LIHC trans rs2026037 1.000 rs2026037 chr9:23762529 C/T cg18828137 chr12:52968145 KRT74 -0.22 -6.07 -0.31 3.4e-9 Intelligence (multi-trait analysis); LIHC cis rs10752881 1.000 rs12126434 chr1:182988414 A/G ch.1.3577855R chr1:183094577 LAMC1 -0.61 -10.64 -0.5 5.03e-23 Colorectal cancer; LIHC cis rs2243480 1.000 rs958550 chr7:65635679 C/T cg07424592 chr7:64974309 NA -0.66 -7.57 -0.38 3.52e-13 Diabetic kidney disease; LIHC cis rs9543976 0.858 rs8192763 chr13:76179170 A/T cg01531495 chr13:76123901 UCHL3 0.48 5.76 0.3 1.87e-8 Diabetic retinopathy; LIHC cis rs2303759 0.830 rs7257053 chr19:49894456 C/G cg22307029 chr19:49891270 CCDC155 0.58 9.22 0.45 3.13e-18 Multiple sclerosis; LIHC cis rs9611565 0.572 rs139569 chr22:42211141 A/G cg03806693 chr22:41940476 POLR3H -0.74 -8.34 -0.41 1.86e-15 Vitiligo; LIHC cis rs67478160 0.643 rs876002 chr14:104239697 G/A cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.75 -0.39 1.09e-13 Schizophrenia; LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC trans rs2122469 0.655 rs17576178 chr8:20581162 T/C cg20211604 chr17:11632341 DNAH9 0.47 6.27 0.32 1.11e-9 Serum tamsulosin hydrochloride concentration; LIHC cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs225245 0.610 rs321608 chr17:33880636 A/G cg05299278 chr17:33885742 SLFN14 0.23 6.06 0.31 3.62e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs2932538 0.922 rs12758377 chr1:113137221 C/A cg22162597 chr1:113214053 CAPZA1 0.73 11.1 0.51 1.2e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.67 -9.87 -0.47 2.21e-20 Lymphocyte counts; LIHC cis rs6430585 0.697 rs7607174 chr2:136513670 T/A cg07169764 chr2:136633963 MCM6 1.15 16.07 0.66 1.08e-43 Corneal structure; LIHC cis rs62064224 0.702 rs735555 chr17:30817450 A/G cg25833597 chr17:30823145 MYO1D -0.49 -6.0 -0.31 4.91e-9 Schizophrenia; LIHC cis rs9517320 1.000 rs9584857 chr13:99128572 T/C cg07423050 chr13:99094983 FARP1 0.35 5.78 0.3 1.68e-8 Longevity; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs743757 1.000 rs2298955 chr3:50431194 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.43 -6.47 -0.33 3.36e-10 Diastolic blood pressure; LIHC cis rs2197308 0.594 rs9705810 chr12:37895003 G/A cg26384229 chr12:38710491 ALG10B -0.46 -6.35 -0.32 6.74e-10 Morning vs. evening chronotype; LIHC cis rs882732 1.000 rs10146582 chr14:95037778 G/A cg14866387 chr14:95027382 SERPINA4 -0.49 -6.66 -0.34 1.08e-10 Blood protein levels; LIHC trans rs2727020 0.729 rs10742932 chr11:49173234 T/C cg15704280 chr7:45808275 SEPT13 -0.87 -16.07 -0.66 1.14e-43 Coronary artery disease; LIHC cis rs6558530 0.692 rs6558521 chr8:1700818 C/T cg24391279 chr8:1708526 NA 0.38 6.11 0.31 2.77e-9 Systolic blood pressure; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg22903471 chr2:27725779 GCKR -0.48 -8.22 -0.41 4.17e-15 Total body bone mineral density; LIHC cis rs9640161 0.742 rs2159235 chr7:150017228 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -8.09 -0.4 1.08e-14 Blood protein levels;Circulating chemerin levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21515243 chr18:21033072 RIOK3 0.42 7.0 0.35 1.34e-11 Cognitive function; LIHC cis rs6594499 0.872 rs7723819 chr5:110427347 A/G cg04022379 chr5:110408740 TSLP -0.55 -9.62 -0.46 1.55e-19 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9902453 0.740 rs2617884 chr17:28120430 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs41271473 0.526 rs10916343 chr1:228727961 C/T cg10167378 chr1:228756711 NA 0.67 6.77 0.34 5.65e-11 Chronic lymphocytic leukemia; LIHC cis rs8062405 0.755 rs17707300 chr16:28593347 A/G cg16576597 chr16:28551801 NUPR1 0.44 6.73 0.34 6.95e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg00656387 chr3:40428638 ENTPD3 0.49 8.31 0.41 2.24e-15 Renal cell carcinoma; LIHC cis rs1005277 0.579 rs1614236 chr10:38502996 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.45 -6.53 -0.33 2.41e-10 Extrinsic epigenetic age acceleration; LIHC cis rs116095464 0.558 rs1812843 chr5:267658 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.66 -0.5 4.18e-23 Breast cancer; LIHC cis rs7264396 0.635 rs6060681 chr20:34506147 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.58 -0.5 8.09e-23 Total cholesterol levels; LIHC cis rs765787 0.530 rs4775834 chr15:45537511 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs9916302 0.904 rs3744348 chr17:37417575 C/G cg07936489 chr17:37558343 FBXL20 -0.84 -13.75 -0.6 1.47e-34 Glomerular filtration rate (creatinine); LIHC cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg12310025 chr6:25882481 NA -0.62 -8.78 -0.43 8.07e-17 Blood metabolite levels; LIHC cis rs637571 0.522 rs7105628 chr11:65763067 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.96 0.31 6.19e-9 Eosinophil percentage of white cells; LIHC trans rs11098499 0.722 rs28713555 chr4:120251995 C/T cg25214090 chr10:38739885 LOC399744 0.51 8.25 0.41 3.48e-15 Corneal astigmatism; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.79 -0.3 1.56e-8 Total body bone mineral density; LIHC cis rs7772486 0.686 rs1004752 chr6:146037822 G/A cg23711669 chr6:146136114 FBXO30 -0.63 -11.66 -0.53 1.13e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2204008 0.505 rs11182550 chr12:38570061 A/T cg26384229 chr12:38710491 ALG10B 0.42 6.4 0.33 4.98e-10 Bladder cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02706910 chr19:24269975 ZNF254 0.46 6.4 0.33 5.25e-10 Hepatitis; LIHC cis rs1568889 1.000 rs34140872 chr11:28335872 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.91 0.35 2.36e-11 Bipolar disorder; LIHC cis rs1790761 0.667 rs1254123 chr11:67334812 T/C cg01069141 chr11:67398826 TBX10;NUDT8 0.36 6.4 0.33 5.1e-10 Mean corpuscular volume; LIHC cis rs9807989 0.507 rs13021177 chr2:103056493 A/G cg03938978 chr2:103052716 IL18RAP 0.31 5.99 0.31 5.35e-9 Asthma; LIHC cis rs7647973 1.000 rs6446275 chr3:49466871 A/G cg07636037 chr3:49044803 WDR6 -0.54 -6.68 -0.34 9.5e-11 Menarche (age at onset); LIHC cis rs2280018 0.581 rs7404524 chr16:15129158 A/G cg07549590 chr16:15018862 NA -0.33 -6.16 -0.32 1.99e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs17685 0.672 rs1639618 chr7:75701987 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1018836 0.923 rs13259842 chr8:91550819 A/G cg16814680 chr8:91681699 NA -0.65 -10.52 -0.49 1.28e-22 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs2727020 0.521 rs7131163 chr11:49574774 C/T cg18944383 chr4:111397179 ENPEP 0.35 8.19 0.4 5.35e-15 Coronary artery disease; LIHC cis rs2282802 0.685 rs2337081 chr5:139642414 A/C cg26211634 chr5:139558579 C5orf32 0.39 5.97 0.31 6.1e-9 Intelligence (multi-trait analysis); LIHC cis rs28489187 0.706 rs233095 chr1:85824816 T/C cg16011679 chr1:85725395 C1orf52 0.46 5.82 0.3 1.33e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs67311347 0.910 rs7617361 chr3:40373259 G/T cg24209194 chr3:40518798 ZNF619 0.41 5.9 0.3 8.8e-9 Renal cell carcinoma; LIHC cis rs9910055 0.529 rs228764 chr17:42185469 A/G cg19774624 chr17:42201019 HDAC5 0.48 6.06 0.31 3.69e-9 Total body bone mineral density; LIHC cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg00091569 chr3:40428383 ENTPD3 -0.37 -6.34 -0.32 7.31e-10 Renal cell carcinoma; LIHC cis rs1395 0.634 rs72817542 chr2:27526681 C/G cg21248554 chr2:27665150 KRTCAP3 -0.5 -6.03 -0.31 4.29e-9 Blood metabolite levels; LIHC cis rs3020736 0.500 rs6002616 chr22:42504679 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.26 -0.32 1.15e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs72772090 0.634 rs12186366 chr5:96088850 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.63 -7.08 -0.36 8.02e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs8060686 0.641 rs73612208 chr16:68206844 G/A cg05110241 chr16:68378359 PRMT7 -0.53 -6.18 -0.32 1.86e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs3806843 0.568 rs2530232 chr5:140082878 A/G cg19875535 chr5:140030758 IK -0.41 -6.59 -0.34 1.66e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg17554472 chr22:41940697 POLR3H -0.54 -5.87 -0.3 1.05e-8 Vitiligo; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg00280220 chr17:61926910 NA 0.43 6.79 0.34 4.99e-11 Prudent dietary pattern; LIHC cis rs10423674 0.526 rs34482977 chr19:18824038 C/G cg16673477 chr19:18812017 CRTC1 -0.41 -6.5 -0.33 2.82e-10 Menarche (age at onset); LIHC cis rs7208859 0.623 rs11657391 chr17:29194287 G/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4665809 1.000 rs1470097 chr2:26312840 A/G cg04944784 chr2:26401820 FAM59B -0.65 -8.26 -0.41 3.25e-15 Gut microbiome composition (summer); LIHC cis rs7078219 0.543 rs4919342 chr10:101282553 G/C cg06854084 chr10:101292507 NKX2-3 -0.34 -6.09 -0.31 2.96e-9 Dental caries; LIHC cis rs875971 0.929 rs4122249 chr7:65920936 T/C cg11764359 chr7:65958608 NA 0.87 15.58 0.64 9.5e-42 Aortic root size; LIHC trans rs2262909 0.962 rs12609368 chr19:22263996 T/C cg17074339 chr11:11642133 GALNTL4 0.4 6.07 0.31 3.37e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs6430585 0.528 rs721765 chr2:136748779 C/A cg07169764 chr2:136633963 MCM6 1.28 20.79 0.75 1.25e-62 Corneal structure; LIHC cis rs7412746 0.611 rs4509581 chr1:150774465 A/G cg17724175 chr1:150552817 MCL1 0.47 9.23 0.45 2.9e-18 Melanoma; LIHC cis rs910316 0.712 rs10131894 chr14:75446879 C/G cg11812906 chr14:75593930 NEK9 0.73 13.49 0.59 1.47e-33 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19775406 chr17:5390252 MIS12;DERL2 0.42 6.31 0.32 8.82e-10 Cognitive function; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg22649068 chr1:150552352 MCL1 -0.54 -6.36 -0.33 6.35e-10 Systolic blood pressure; LIHC cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg08067268 chr2:26466485 HADHB;HADHA 0.51 7.42 0.37 9.53e-13 Gut microbiome composition (summer); LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg21565150 chr10:90751097 FAS;ACTA2 -0.48 -6.3 -0.32 9.16e-10 Electroencephalogram traits; LIHC cis rs9911578 0.935 rs34523895 chr17:57034095 T/C cg12560992 chr17:57184187 TRIM37 0.9 15.97 0.65 2.79e-43 Intelligence (multi-trait analysis); LIHC cis rs6882046 0.513 rs601942 chr5:88031820 T/C cg22951263 chr5:87985283 NA -0.39 -6.8 -0.35 4.61e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs8016982 0.662 rs1951616 chr14:81671752 T/C cg01989461 chr14:81687754 GTF2A1 0.53 9.25 0.45 2.52e-18 Schizophrenia; LIHC cis rs116095464 0.558 rs62347678 chr5:227496 A/G cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs7647973 0.506 rs11920251 chr3:49356671 C/T cg06212747 chr3:49208901 KLHDC8B 0.46 6.12 0.31 2.5e-9 Menarche (age at onset); LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.14e-13 Total body bone mineral density; LIHC cis rs17125944 0.505 rs77949716 chr14:53204234 G/A cg00686598 chr14:53173677 PSMC6 1.29 15.79 0.65 1.44e-42 Alzheimer's disease (late onset); LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs7249142 0.562 rs10417796 chr19:19287072 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.42 -6.99 -0.35 1.44e-11 IgG glycosylation; LIHC cis rs4660261 0.526 rs810680 chr1:44347856 C/T cg12908607 chr1:44402522 ARTN -0.46 -7.9 -0.39 3.89e-14 Intelligence (multi-trait analysis); LIHC cis rs35883536 0.647 rs12043865 chr1:101042651 G/A cg14515779 chr1:101123966 NA 0.46 6.6 0.34 1.61e-10 Monocyte count; LIHC cis rs67478160 0.643 rs8003653 chr14:104298836 A/G cg24130564 chr14:104152367 KLC1 -0.35 -5.82 -0.3 1.34e-8 Schizophrenia; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05106659 chr4:152682899 PET112L -0.36 -6.43 -0.33 4.39e-10 Calcium levels; LIHC cis rs3736757 0.603 rs10911631 chr1:184651867 A/C cg07817967 chr1:184721222 EDEM3 0.36 5.76 0.3 1.84e-8 Obesity-related traits; LIHC cis rs6500602 0.929 rs6500603 chr16:4497537 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.45 6.89 0.35 2.77e-11 Schizophrenia; LIHC cis rs752010 0.808 rs7529858 chr1:42086606 G/C cg06885757 chr1:42089581 HIVEP3 0.31 6.5 0.33 2.9e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs9921222 0.500 rs12917907 chr16:405866 C/T cg08923669 chr16:420230 MRPL28 -0.45 -6.18 -0.32 1.79e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs6714710 0.580 rs13032265 chr2:98409565 T/C cg26665480 chr2:98280029 ACTR1B 0.43 6.05 0.31 3.87e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs6754311 0.731 rs3754686 chr2:136603276 T/C cg07169764 chr2:136633963 MCM6 -0.67 -10.09 -0.48 3.91e-21 Mosquito bite size; LIHC cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg20607798 chr8:58055168 NA 0.67 7.7 0.38 1.48e-13 Developmental language disorder (linguistic errors); LIHC cis rs17539620 0.624 rs871069 chr6:154837578 A/C cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26755928 chr19:10363173 MRPL4 0.44 6.19 0.32 1.68e-9 Pancreatic cancer; LIHC cis rs763121 0.626 rs5750643 chr22:39009017 A/G cg06022373 chr22:39101656 GTPBP1 0.73 14.67 0.62 3.87e-38 Menopause (age at onset); LIHC cis rs8010715 0.848 rs927494 chr14:24600390 A/T cg23112188 chr14:24563095 PCK2 -0.32 -6.35 -0.32 6.94e-10 IgG glycosylation; LIHC cis rs67478160 0.643 rs2887282 chr14:104280734 A/G cg01849466 chr14:104193079 ZFYVE21 -0.42 -6.52 -0.33 2.56e-10 Schizophrenia; LIHC cis rs17106184 1.000 rs12089041 chr1:51381594 C/T cg07174182 chr1:51127561 FAF1 -0.75 -8.06 -0.4 1.32e-14 Type 2 diabetes; LIHC cis rs1982963 1.000 rs3818187 chr14:52509788 A/G cg10843707 chr14:52510701 NID2 0.46 8.36 0.41 1.55e-15 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2976388 1.000 rs2976392 chr8:143762932 G/A cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs986417 0.901 rs4901989 chr14:61014743 G/C cg27398547 chr14:60952738 C14orf39 0.74 8.02 0.4 1.71e-14 Gut microbiota (bacterial taxa); LIHC cis rs2230307 0.536 rs631977 chr1:100544564 C/G cg24955406 chr1:100503596 HIAT1 0.6 5.99 0.31 5.44e-9 Carotid intima media thickness; LIHC cis rs8113613 0.656 rs1059840 chr19:10370490 A/T cg01850179 chr19:10340795 S1PR2 0.54 6.45 0.33 3.88e-10 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs780096 0.527 rs12471703 chr2:27738854 C/T cg05484376 chr2:27715224 FNDC4 0.4 6.67 0.34 1.02e-10 Total body bone mineral density; LIHC cis rs4065321 0.522 rs34648856 chr17:38149411 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.77 15.18 0.63 3.75e-40 White blood cell count (basophil);White blood cell count; LIHC cis rs7772486 0.686 rs702314 chr6:146003510 G/A cg23711669 chr6:146136114 FBXO30 -0.63 -11.34 -0.52 1.57e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.71 -0.3 2.45e-8 Total body bone mineral density; LIHC cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs55665837 0.524 rs2882128 chr11:14414634 A/C cg19336497 chr11:14380999 RRAS2 -0.55 -10.35 -0.49 5.08e-22 Vitamin D levels; LIHC cis rs7582720 1.000 rs72934706 chr2:203707752 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.03 0.31 4.27e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10256972 0.706 rs12701969 chr7:1121849 A/G cg22907277 chr7:1156413 C7orf50 0.51 7.55 0.38 3.95e-13 Longevity;Endometriosis; LIHC cis rs2073300 1.000 rs6048803 chr20:23438889 A/G cg16736954 chr20:23401023 NAPB 0.52 5.82 0.3 1.36e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11252926 0.528 rs11252090 chr10:436547 C/T cg16346588 chr10:242978 ZMYND11 -0.39 -5.95 -0.31 6.61e-9 Psychosis in Alzheimer's disease; LIHC cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg04317338 chr11:64019027 PLCB3 0.87 10.96 0.51 3.84e-24 Mean platelet volume; LIHC cis rs244731 0.959 rs6872021 chr5:176610012 G/A cg16006841 chr5:176797999 RGS14 -0.61 -5.9 -0.3 8.67e-9 Urate levels in lean individuals; LIHC cis rs3806843 0.932 rs2563256 chr5:140141779 G/T cg19875535 chr5:140030758 IK -0.37 -5.98 -0.31 5.72e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1419980 0.730 rs11525576 chr12:7752041 A/G cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs7927771 0.832 rs11607981 chr11:47401060 T/G cg20307385 chr11:47447363 PSMC3 -0.44 -5.71 -0.3 2.45e-8 Subjective well-being; LIHC cis rs7959452 0.590 rs7968629 chr12:69782857 G/A cg20891283 chr12:69753455 YEATS4 0.9 19.49 0.73 1.94e-57 Blood protein levels; LIHC cis rs1559088 0.576 rs4805852 chr19:33609441 C/T cg17764715 chr19:33622953 WDR88 0.57 7.94 0.39 2.94e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6459788 0.720 rs11974772 chr7:157250645 G/A cg06271696 chr7:157225062 NA -0.5 -7.99 -0.4 2.07e-14 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs1707322 0.721 rs12069121 chr1:46231984 G/A cg03146154 chr1:46216737 IPP 0.58 9.58 0.46 2.03e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7712401 0.791 rs1531340 chr5:122108017 G/A cg18764291 chr5:122110994 SNX2 0.36 6.12 0.31 2.54e-9 Mean platelet volume; LIHC cis rs77106637 0.769 rs11603313 chr11:72588177 G/A cg03713592 chr11:72463424 ARAP1 0.87 7.86 0.39 4.95e-14 Type 2 diabetes; LIHC cis rs10193935 0.818 rs2374428 chr2:42667961 T/C cg27598129 chr2:42591480 NA 0.72 10.84 0.51 1.03e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.94 0.44 2.39e-17 Platelet count; LIHC cis rs10847980 0.590 rs79798267 chr12:123321819 A/T cg22842854 chr12:123319900 HIP1R 0.82 9.22 0.45 3.08e-18 Adiponectin levels; LIHC cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg08888203 chr3:10149979 C3orf24 0.61 6.88 0.35 2.78e-11 Alzheimer's disease; LIHC cis rs4713118 0.662 rs9468274 chr6:28026077 G/T cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs7937682 0.889 rs11213969 chr11:111528441 A/G cg09085632 chr11:111637200 PPP2R1B -1.06 -13.58 -0.59 6.77e-34 Primary sclerosing cholangitis; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg26338869 chr17:61819248 STRADA 0.59 8.72 0.43 1.25e-16 Prudent dietary pattern; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg24693881 chr1:107596107 NA 0.47 7.88 0.39 4.5e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6752107 0.935 rs10929326 chr2:234151045 T/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.46 6.89 0.35 2.75e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs903552 0.800 rs6598478 chr15:102001696 A/T cg25677261 chr15:102009856 PCSK6 -0.45 -5.88 -0.3 9.92e-9 Diabetic kidney disease; LIHC cis rs903552 0.736 rs2412008 chr15:102006841 C/T cg04789225 chr15:102009795 PCSK6 -0.44 -5.76 -0.3 1.88e-8 Diabetic kidney disease; LIHC cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg03806693 chr22:41940476 POLR3H 1.08 12.74 0.57 1.13e-30 Vitiligo; LIHC cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.54 -9.03 -0.44 1.31e-17 Bipolar disorder; LIHC cis rs61712019 0.563 rs34996456 chr2:77731311 G/A cg11252801 chr2:77748917 LRRTM4 0.45 6.21 0.32 1.57e-9 Schizophrenia; LIHC cis rs1198430 0.683 rs1198433 chr1:23756695 A/G cg13183780 chr1:23809682 ASAP3 -0.39 -6.72 -0.34 7.78e-11 Total cholesterol levels; LIHC cis rs12960505 0.506 rs9950293 chr18:51055233 C/A cg24270629 chr18:50823537 DCC -0.46 -6.28 -0.32 1.04e-9 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.909 rs10026736 chr4:120384322 G/C cg09307838 chr4:120376055 NA 0.75 11.29 0.52 2.42e-25 Corneal astigmatism; LIHC trans rs9914544 0.545 rs12451200 chr17:18778493 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.59 -0.34 1.68e-10 Educational attainment (years of education); LIHC cis rs8017423 0.967 rs11621431 chr14:90709221 C/T cg14092571 chr14:90743983 NA -0.36 -5.73 -0.3 2.16e-8 Mortality in heart failure; LIHC cis rs1691799 0.867 rs1168333 chr12:66761377 G/A cg16791601 chr12:66731901 HELB -0.43 -9.21 -0.45 3.33e-18 White blood cell count (basophil); LIHC cis rs2108622 0.727 rs8104311 chr19:15982760 T/C cg13772218 chr19:15982569 NA 0.37 7.75 0.39 1.06e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs6500602 0.592 rs4785966 chr16:4518754 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.52 -8.07 -0.4 1.21e-14 Schizophrenia; LIHC cis rs9457247 0.534 rs4710154 chr6:167394634 A/T cg12798992 chr6:167411361 FGFR1OP -0.48 -7.79 -0.39 8.26e-14 Crohn's disease; LIHC cis rs67460515 0.892 rs13073147 chr3:161045237 T/C cg17135325 chr3:160939158 NMD3 0.57 8.13 0.4 7.9e-15 Parkinson's disease; LIHC cis rs9388451 0.626 rs3799712 chr6:126075103 A/G cg05901451 chr6:126070800 HEY2 -0.69 -14.51 -0.62 1.58e-37 Brugada syndrome; LIHC cis rs1538970 1.000 rs2492840 chr1:45849792 C/A cg05343316 chr1:45956843 TESK2 0.55 8.32 0.41 2.12e-15 Platelet count; LIHC cis rs6582630 0.638 rs12425531 chr12:38550387 A/G cg26384229 chr12:38710491 ALG10B -0.49 -6.85 -0.35 3.55e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs950169 0.959 rs12902070 chr15:84793558 T/C cg17507749 chr15:85114479 UBE2QP1 0.76 7.71 0.38 1.37e-13 Schizophrenia; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs9896052 0.580 rs6416847 chr17:73468434 G/A cg25649188 chr17:73499917 CASKIN2 0.5 7.43 0.37 8.98e-13 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs7917772 0.582 rs10786682 chr10:104318322 A/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.85 -0.39 5.27e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7647973 0.593 rs55997059 chr3:49858661 A/T cg03060546 chr3:49711283 APEH -0.6 -7.19 -0.36 4.18e-12 Menarche (age at onset); LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg24209194 chr3:40518798 ZNF619 0.65 10.0 0.48 7.98e-21 Renal cell carcinoma; LIHC cis rs3806843 0.766 rs801399 chr5:140034844 C/T cg16179182 chr5:140090404 VTRNA1-1 0.35 5.72 0.3 2.3e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs4788570 0.655 rs1392484 chr16:71822101 T/A cg06353428 chr16:71660113 MARVELD3 1.33 14.27 0.61 1.38e-36 Intelligence (multi-trait analysis); LIHC cis rs3806843 1.000 rs12717860 chr5:140171442 C/T cg19875535 chr5:140030758 IK 0.36 5.82 0.3 1.39e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg05564831 chr3:52568323 NT5DC2 0.35 5.73 0.3 2.25e-8 Electroencephalogram traits; LIHC cis rs2204008 0.774 rs8189620 chr12:38241621 A/G cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.56e-8 Bladder cancer; LIHC cis rs10493773 1.000 rs3767163 chr1:86121895 T/G cg17807903 chr1:86174739 ZNHIT6 -0.49 -7.4 -0.37 1.1e-12 Urate levels in overweight individuals; LIHC cis rs11608355 0.705 rs6663 chr12:109886603 G/A cg04065206 chr12:109973212 UBE3B -0.49 -6.02 -0.31 4.51e-9 Neuroticism; LIHC cis rs797680 0.856 rs7540025 chr1:93759228 C/T cg15093775 chr1:93646470 TMED5;CCDC18 0.34 6.12 0.31 2.6e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg21877656 chr19:58662188 ZNF329 1.07 8.34 0.41 1.83e-15 Cholesterol, total; LIHC cis rs703842 1.000 rs6581155 chr12:58178162 A/G cg18357645 chr12:58087776 OS9 -0.43 -6.83 -0.35 3.82e-11 Multiple sclerosis; LIHC trans rs877282 0.898 rs12356744 chr10:757477 G/C cg22713356 chr15:30763199 NA 1.42 12.22 0.55 9.43e-29 Uric acid levels; LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg17178900 chr1:205818956 PM20D1 0.66 9.78 0.47 4.36e-20 Menarche (age at onset); LIHC cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.73 0.39 1.19e-13 Bipolar disorder; LIHC cis rs6695567 1.000 rs6672276 chr1:53629901 C/A cg20326410 chr1:53600821 SLC1A7 0.3 6.34 0.32 7.26e-10 Systemic lupus erythematosus; LIHC cis rs2075371 0.932 rs1035328 chr7:133978419 T/C cg20476274 chr7:133979776 SLC35B4 0.73 11.96 0.54 8.98e-28 Mean platelet volume; LIHC cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.22e-8 Menopause (age at onset); LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg26338869 chr17:61819248 STRADA 0.59 8.63 0.42 2.41e-16 Prudent dietary pattern; LIHC cis rs796364 0.762 rs13030712 chr2:200973569 G/A cg23649088 chr2:200775458 C2orf69 0.49 6.96 0.35 1.76e-11 Schizophrenia; LIHC cis rs72627123 0.582 rs62005102 chr14:74500586 T/A cg05179529 chr14:74551516 LIN52;ALDH6A1 0.49 6.43 0.33 4.3e-10 Morning vs. evening chronotype; LIHC trans rs916888 0.821 rs70602 chr17:44859715 T/C cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs992157 0.798 rs12053514 chr2:219167965 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.75 -11.85 -0.54 2.34e-27 Colorectal cancer; LIHC cis rs2932538 0.922 rs7527076 chr1:113150481 G/A cg22162597 chr1:113214053 CAPZA1 0.73 11.15 0.52 7.68e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1577917 0.958 rs2875456 chr6:86602284 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.54 -0.5 1.11e-22 Response to antipsychotic treatment; LIHC cis rs11122272 0.735 rs2486735 chr1:231521778 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs11676348 0.791 rs6726126 chr2:218952233 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.42 -5.74 -0.3 2.06e-8 Ulcerative colitis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14166846 chr1:220268091 IARS2 0.49 7.58 0.38 3.38e-13 Pancreatic cancer; LIHC cis rs860295 0.812 rs11264413 chr1:155788656 G/A cg02153340 chr1:155202674 NA -0.34 -6.12 -0.31 2.52e-9 Body mass index; LIHC cis rs10464366 0.544 rs12701697 chr7:39182165 C/T cg10621924 chr7:39171070 POU6F2 0.41 6.45 0.33 3.86e-10 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10198271 chr20:55966838 RBM38 -0.46 -6.76 -0.34 5.81e-11 Cognitive function; LIHC cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs2455601 1.000 rs12418190 chr11:8899818 G/C cg21881798 chr11:8931708 C11orf17;ST5 -0.5 -6.51 -0.33 2.63e-10 Schizophrenia; LIHC trans rs617791 0.569 rs11227370 chr11:65747693 C/T cg17712092 chr4:129076599 LARP1B -0.56 -6.8 -0.35 4.55e-11 Breast cancer; LIHC cis rs250677 0.687 rs3095947 chr5:148436728 T/C cg12140854 chr5:148520817 ABLIM3 -0.45 -6.1 -0.31 2.85e-9 Breast cancer; LIHC cis rs7165170 0.549 rs11635656 chr15:91103096 A/G cg26821196 chr15:91095069 CRTC3 0.4 7.08 0.36 8.28e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg08280861 chr8:58055591 NA 0.5 6.06 0.31 3.5e-9 Developmental language disorder (linguistic errors); LIHC cis rs9309473 0.948 rs10199224 chr2:73761446 C/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.72 -0.34 7.52e-11 Metabolite levels; LIHC cis rs6061231 0.561 rs67072353 chr20:60940702 G/A cg03945807 chr20:60948434 NA 0.46 5.81 0.3 1.41e-8 Colorectal cancer; LIHC trans rs7618501 0.932 rs4855850 chr3:49761571 G/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs3782089 0.744 rs11545200 chr11:65319751 G/A cg21890820 chr11:65308645 LTBP3 0.92 6.53 0.33 2.33e-10 Height; LIHC cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg07414643 chr4:187882934 NA -0.24 -6.03 -0.31 4.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769765 0.913 rs28670284 chr22:50221973 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.79 -8.28 -0.41 2.84e-15 Schizophrenia; LIHC cis rs765787 0.530 rs2554457 chr15:45520926 G/A cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.73 -0.3 2.15e-8 Uric acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27209117 chr17:58469727 USP32 0.48 6.98 0.35 1.52e-11 Pancreatic cancer; LIHC cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.53 7.88 0.39 4.31e-14 Menarche (age at onset); LIHC cis rs9303401 0.659 rs17222523 chr17:56620501 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.12 0.55 2.35e-28 Cognitive test performance; LIHC cis rs2976388 1.000 rs2976396 chr8:143764001 A/G cg06565975 chr8:143823917 SLURP1 0.3 5.77 0.3 1.74e-8 Urinary tract infection frequency; LIHC cis rs10089 0.953 rs6887674 chr5:127531183 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.5 0.33 2.87e-10 Ileal carcinoids; LIHC cis rs7923837 0.616 rs12778642 chr10:94464307 G/T cg25506282 chr10:94462361 NA 0.43 7.59 0.38 2.97e-13 Body mass index;Multiple sclerosis; LIHC cis rs12286929 0.839 rs12803174 chr11:115023159 T/C cg04055981 chr11:115044050 NA 0.45 6.7 0.34 8.7e-11 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9457247 0.663 rs9295384 chr6:167448113 T/A cg23791538 chr6:167370224 RNASET2 -0.55 -8.82 -0.43 5.86e-17 Crohn's disease; LIHC cis rs7582720 1.000 rs72936830 chr2:203769803 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg02951883 chr7:2050386 MAD1L1 -0.62 -9.68 -0.46 9.67e-20 Bipolar disorder and schizophrenia; LIHC cis rs4919694 1.000 rs111622998 chr10:104953021 C/A cg04362960 chr10:104952993 NT5C2 1.06 8.42 0.41 1.05e-15 Arsenic metabolism; LIHC cis rs5769765 0.954 rs1569954 chr22:50244071 C/T cg02269571 chr22:50332266 NA 0.58 8.24 0.41 3.71e-15 Schizophrenia; LIHC trans rs2739330 0.753 rs4822452 chr22:24254363 C/T cg06437703 chr8:37914619 EIF4EBP1 -0.5 -7.34 -0.37 1.58e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs10861342 1.000 rs11112380 chr12:105526695 C/T cg23923672 chr12:105501055 KIAA1033 0.66 7.7 0.38 1.44e-13 IgG glycosylation; LIHC cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs2971970 0.539 rs2971972 chr7:133644200 A/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.8 -0.3 1.52e-8 Intelligence (multi-trait analysis); LIHC cis rs4705952 1.000 rs4705952 chr5:131839618 A/G cg02551604 chr5:131831745 NA 0.39 6.16 0.32 1.99e-9 C-reactive protein levels; LIHC cis rs7937682 1.000 rs11608122 chr11:111535105 C/T cg09085632 chr11:111637200 PPP2R1B 1.05 12.79 0.57 7.01e-31 Primary sclerosing cholangitis; LIHC cis rs3015497 0.789 rs8003372 chr14:51102351 G/A cg09863266 chr14:51125203 SAV1 -0.43 -6.85 -0.35 3.53e-11 Mean platelet volume; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.0 -0.31 5.01e-9 Diastolic blood pressure; LIHC cis rs67460515 0.892 rs10513564 chr3:161059762 A/G cg17135325 chr3:160939158 NMD3 0.57 8.22 0.41 4.39e-15 Parkinson's disease; LIHC trans rs1814175 0.645 rs28454367 chr11:50045708 G/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs921968 0.643 rs497983 chr2:219415189 A/G cg17980119 chr2:219472607 PLCD4 0.36 6.08 0.31 3.14e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs9814567 1.000 rs9989967 chr3:134238964 A/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs875971 0.545 rs4441996 chr7:65588220 T/C cg26939375 chr7:64535504 NA -0.41 -6.5 -0.33 2.79e-10 Aortic root size; LIHC cis rs6500602 0.647 rs4785967 chr16:4523208 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.45 6.27 0.32 1.07e-9 Schizophrenia; LIHC cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.13e-9 Menopause (age at onset); LIHC cis rs9517320 0.967 rs2274056 chr13:99134839 G/C cg07423050 chr13:99094983 FARP1 0.35 5.77 0.3 1.8e-8 Longevity; LIHC cis rs11122272 0.735 rs2355872 chr1:231478489 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.65 -0.5 4.68e-23 Hemoglobin concentration; LIHC cis rs4819052 0.851 rs35064782 chr21:46674360 G/A cg11663144 chr21:46675770 NA -0.32 -5.85 -0.3 1.16e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg02951883 chr7:2050386 MAD1L1 -0.68 -11.17 -0.52 6.71e-25 Bipolar disorder and schizophrenia; LIHC cis rs5769765 0.862 rs138856 chr22:50199378 G/T cg26441486 chr22:50317300 CRELD2 0.37 6.08 0.31 3.19e-9 Schizophrenia; LIHC cis rs9486719 1.000 rs12190508 chr6:96898269 T/C cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.32e-12 Migraine;Coronary artery disease; LIHC cis rs9790314 1.000 rs336570 chr3:161072054 A/G cg03342759 chr3:160939853 NMD3 0.69 8.45 0.42 8.6e-16 Morning vs. evening chronotype; LIHC cis rs8017423 0.647 rs12883357 chr14:90815032 A/G cg04374321 chr14:90722782 PSMC1 -0.51 -7.4 -0.37 1.08e-12 Mortality in heart failure; LIHC cis rs2303759 0.830 rs7257053 chr19:49894456 C/G cg05022225 chr19:49866942 DKKL1;TEAD2 0.58 8.94 0.44 2.52e-17 Multiple sclerosis; LIHC cis rs3859192 0.561 rs34453912 chr17:38180352 T/A cg17344932 chr17:38183730 MED24;SNORD124 0.8 16.11 0.66 7.72e-44 White blood cell count; LIHC cis rs36051895 0.623 rs10975023 chr9:5239549 A/G cg02405213 chr9:5042618 JAK2 0.65 10.72 0.5 2.72e-23 Pediatric autoimmune diseases; LIHC cis rs2273156 0.706 rs8015622 chr14:35487100 G/A cg16230307 chr14:35515116 FAM177A1 -0.43 -6.19 -0.32 1.68e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs208520 0.690 rs2126120 chr6:66742754 A/G cg07460842 chr6:66804631 NA 0.78 9.07 0.44 9.76e-18 Exhaled nitric oxide output; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12090654 chr8:6424636 MCPH1 0.46 6.78 0.34 5.21e-11 Longevity; LIHC cis rs2439831 1.000 rs690316 chr15:43737880 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.68 0.59 2.81e-34 Lung cancer in ever smokers; LIHC cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg12311346 chr5:56204834 C5orf35 -0.57 -7.53 -0.38 4.53e-13 Initial pursuit acceleration; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg27313007 chr17:78617750 RPTOR 0.46 6.12 0.31 2.52e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs10078 0.571 rs2241597 chr5:480509 A/G cg08916839 chr5:415575 AHRR 0.6 12.77 0.57 8.28e-31 Fat distribution (HIV); LIHC cis rs597539 0.652 rs478647 chr11:68700424 C/T cg04772025 chr11:68637568 NA 0.49 6.36 0.33 6.32e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs73186030 0.920 rs73186060 chr3:122052354 T/G cg13973942 chr17:977984 ABR 0.47 6.06 0.31 3.6e-9 Serum parathyroid hormone levels; LIHC cis rs644799 0.965 rs545342 chr11:95545369 T/C cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.79 0.3 1.63e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3741404 0.931 rs594942 chr11:64006292 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 -0.94 -15.35 -0.64 8.07e-41 Platelet count; LIHC cis rs999943 0.739 rs62407633 chr6:33609244 C/T cg14003231 chr6:33640908 ITPR3 0.43 6.97 0.35 1.64e-11 Obesity (extreme); LIHC cis rs600806 0.821 rs3879447 chr1:109891403 C/T cg23091122 chr1:110024289 SYPL2 -0.48 -6.54 -0.33 2.3e-10 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg05368731 chr17:41323189 NBR1 0.71 12.2 0.55 1.17e-28 Menopause (age at onset); LIHC cis rs3812111 0.506 rs1204837 chr6:116514792 G/A cg08036074 chr6:116424633 NT5DC1 -0.41 -6.51 -0.33 2.63e-10 Age-related macular degeneration; LIHC cis rs6499255 1.000 rs11075733 chr16:69773435 G/T cg15192750 chr16:69999425 NA 0.44 6.62 0.34 1.42e-10 IgE levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12484590 chr1:156475177 NA 0.5 6.93 0.35 2.1e-11 Pancreatic cancer; LIHC cis rs10870270 0.830 rs10781571 chr10:133774316 G/C cg26149184 chr10:133730230 NA 0.48 7.52 0.38 4.79e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg26338869 chr17:61819248 STRADA 0.61 8.92 0.43 2.9e-17 Prudent dietary pattern; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg11905131 chr22:24372483 LOC391322 -0.72 -10.92 -0.51 4.96e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg04944784 chr2:26401820 FAM59B 0.72 9.33 0.45 1.36e-18 Gut microbiome composition (summer); LIHC cis rs6963495 0.818 rs6955796 chr7:105170321 T/G cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC trans rs11708189 1.000 rs11708189 chr3:140175360 A/G cg21073520 chr19:19648991 CILP2 0.35 6.11 0.31 2.65e-9 Sudden cardiac arrest; LIHC cis rs7762018 1.000 rs6942332 chr6:170131934 A/G cg19338460 chr6:170058176 WDR27 -0.41 -6.19 -0.32 1.69e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7412746 0.658 rs7526489 chr1:150726238 C/T cg15448220 chr1:150897856 SETDB1 0.43 6.72 0.34 7.76e-11 Melanoma; LIHC cis rs7100689 0.784 rs11202699 chr10:82131453 A/G cg00277334 chr10:82204260 NA -0.54 -6.68 -0.34 9.51e-11 Post bronchodilator FEV1; LIHC cis rs3741151 1.000 rs79794992 chr11:73049352 A/G cg17517138 chr11:73019481 ARHGEF17 0.95 6.93 0.35 2.14e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs12586317 0.508 rs10134914 chr14:35425012 T/G cg16230307 chr14:35515116 FAM177A1 0.65 10.9 0.51 6.12e-24 Psoriasis; LIHC cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg13047869 chr3:10149882 C3orf24 0.51 6.55 0.33 2.05e-10 Alzheimer's disease; LIHC cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg10360323 chr17:41437877 NA 0.41 6.21 0.32 1.52e-9 Menopause (age at onset); LIHC cis rs9952991 0.943 rs9952753 chr18:12780463 A/C cg23598886 chr18:12777645 NA 0.48 6.48 0.33 3.27e-10 Inflammatory skin disease; LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg03517284 chr6:25882590 NA -0.58 -8.5 -0.42 5.96e-16 Blood metabolite levels; LIHC cis rs9457247 0.565 rs12178491 chr6:167512474 C/T cg23791538 chr6:167370224 RNASET2 -0.46 -7.18 -0.36 4.5e-12 Crohn's disease; LIHC cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg11890956 chr21:40555474 PSMG1 1.04 14.97 0.63 2.54e-39 Cognitive function; LIHC cis rs2066819 1.000 rs17118439 chr12:56667604 C/T cg26734620 chr12:56694298 CS -1.18 -10.53 -0.49 1.23e-22 Psoriasis vulgaris; LIHC trans rs10777288 0.561 rs4842747 chr12:91400720 G/A cg03760490 chr1:35245996 GJB3 -0.33 -6.09 -0.31 3e-9 Pulmonary function (smoking interaction); LIHC cis rs896854 0.517 rs2013597 chr8:95951807 G/A cg16049864 chr8:95962084 TP53INP1 -0.48 -7.92 -0.39 3.27e-14 Type 2 diabetes; LIHC cis rs6546550 0.900 rs897122 chr2:70140271 C/T cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC cis rs7428 0.527 rs7608892 chr2:85542718 G/A cg24342717 chr2:85555507 TGOLN2 -0.79 -10.15 -0.48 2.51e-21 Ear protrusion; LIHC trans rs526821 0.595 rs565859 chr11:55297367 T/C cg15704280 chr7:45808275 SEPT13 -0.52 -7.99 -0.4 2.13e-14 Pediatric bone mineral density (spine); LIHC trans rs2727020 0.734 rs1164663 chr11:49294723 A/T cg03929089 chr4:120376271 NA 0.67 9.54 0.46 2.87e-19 Coronary artery disease; LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg11494091 chr17:61959527 GH2 0.45 8.17 0.4 5.93e-15 Prudent dietary pattern; LIHC cis rs11229555 0.645 rs11229460 chr11:58208343 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg24209194 chr3:40518798 ZNF619 0.56 8.13 0.4 8.15e-15 Renal cell carcinoma; LIHC cis rs7264396 0.690 rs2425164 chr20:34434916 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -10.63 -0.5 5.4e-23 Total cholesterol levels; LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg05896524 chr21:47604654 C21orf56 -0.51 -8.23 -0.41 3.91e-15 Testicular germ cell tumor; LIHC cis rs2243480 0.522 rs73150635 chr7:65972490 C/T cg18252515 chr7:66147081 NA -1.32 -15.3 -0.64 1.29e-40 Diabetic kidney disease; LIHC cis rs7613875 0.600 rs2624848 chr3:50165101 T/C cg21467203 chr3:49911342 NA 0.53 9.55 0.46 2.58e-19 Body mass index; LIHC trans rs3112255 1.000 rs3112255 chr2:101317260 C/A cg06958034 chr1:23346203 KDM1A -0.46 -6.05 -0.31 3.73e-9 Intelligence (multi-trait analysis); LIHC cis rs10078 0.515 rs6872510 chr5:481610 T/C cg24955955 chr5:415729 AHRR 0.57 10.45 0.49 2.25e-22 Fat distribution (HIV); LIHC cis rs6964587 0.626 rs4422709 chr7:91510968 A/G cg17063962 chr7:91808500 NA -0.61 -11.01 -0.51 2.52e-24 Breast cancer; LIHC cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg18357526 chr6:26021779 HIST1H4A 1.04 14.7 0.62 3.06e-38 Intelligence (multi-trait analysis); LIHC cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg03264133 chr6:25882463 NA -1.06 -16.34 -0.66 9.22e-45 Uric acid levels; LIHC cis rs6952808 0.929 rs11761270 chr7:1923695 C/T cg22963979 chr7:1858916 MAD1L1 -0.38 -5.96 -0.31 6.37e-9 Bipolar disorder and schizophrenia; LIHC cis rs2742417 0.603 rs6807438 chr3:45778623 G/A cg04837898 chr3:45731254 SACM1L -0.51 -8.51 -0.42 5.56e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs12451471 0.637 rs12950757 chr17:78096800 T/G cg24585782 chr17:78113791 EIF4A3 -0.46 -6.27 -0.32 1.06e-9 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC trans rs5756813 0.661 rs2071910 chr22:38204259 C/T cg19894588 chr14:64061835 NA -0.69 -10.02 -0.48 7.07e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs875971 0.862 rs2088653 chr7:65808608 G/A cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs2635047 0.625 rs1836259 chr18:44732389 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.42 5.99 0.31 5.44e-9 Educational attainment; LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.72 -0.34 7.62e-11 Lymphocyte counts; LIHC trans rs75804782 0.641 rs72985397 chr2:239341354 A/G cg01134436 chr17:81009848 B3GNTL1 0.76 6.36 0.33 6.62e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.9 -10.39 -0.49 3.83e-22 Platelet count; LIHC cis rs7520050 0.933 rs11211203 chr1:46315592 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs651907 0.535 rs2290859 chr3:101525625 C/T cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.92 -0.3 7.85e-9 Colorectal cancer; LIHC cis rs7258465 1.000 rs4595905 chr19:18547305 T/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.29 -0.37 2.13e-12 Breast cancer; LIHC cis rs2836974 0.549 rs34160989 chr21:40554118 C/G cg11890956 chr21:40555474 PSMG1 0.96 9.07 0.44 9.55e-18 Cognitive function; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs1559088 0.948 rs6510346 chr19:33598526 T/A cg17764715 chr19:33622953 WDR88 0.45 6.51 0.33 2.64e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9790314 1.000 rs336583 chr3:161081981 A/T cg04691961 chr3:161091175 C3orf57 0.44 7.02 0.35 1.22e-11 Morning vs. evening chronotype; LIHC cis rs6570726 0.935 rs376991 chr6:145828073 G/C cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs3736594 0.513 rs59876138 chr2:27792323 A/C cg27432699 chr2:27873401 GPN1 0.46 6.76 0.34 6.12e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs4919087 0.748 rs701814 chr10:98975719 C/T cg25902810 chr10:99078978 FRAT1 -0.53 -6.21 -0.32 1.55e-9 Monocyte count; LIHC cis rs6964587 0.869 rs7793946 chr7:91520628 T/C cg17063962 chr7:91808500 NA -0.98 -18.34 -0.7 8.37e-53 Breast cancer; LIHC cis rs17776563 0.887 rs72763807 chr15:89131572 T/C cg05013243 chr15:89149849 MIR1179 0.41 6.81 0.35 4.45e-11 Thyroid hormone levels; LIHC cis rs66887589 0.967 rs56173225 chr4:120509972 G/A cg09307838 chr4:120376055 NA -0.5 -7.53 -0.38 4.55e-13 Diastolic blood pressure; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg16202803 chr2:240014758 HDAC4 0.43 6.37 0.33 6.07e-10 Bilirubin levels; LIHC cis rs1707322 1.000 rs4454479 chr1:46423555 G/A cg03146154 chr1:46216737 IPP 0.48 7.84 0.39 5.74e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2224391 0.822 rs2773321 chr6:5262220 C/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -5.96 -0.31 6.36e-9 Height; LIHC cis rs611744 0.647 rs864166 chr8:109249300 C/G cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs911119 0.954 rs2254635 chr20:23622758 G/T cg16589663 chr20:23618590 CST3 0.71 7.58 0.38 3.25e-13 Chronic kidney disease; LIHC cis rs11955398 0.716 rs2409792 chr5:59998236 A/G cg02684056 chr5:59996105 DEPDC1B 0.4 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg00343986 chr7:65444356 GUSB 0.44 6.26 0.32 1.18e-9 Aortic root size; LIHC cis rs1577917 0.761 rs117452258 chr6:86554211 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC trans rs7618501 0.521 rs2883059 chr3:49902160 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.45 -6.81 -0.35 4.51e-11 Intelligence (multi-trait analysis); LIHC cis rs11758351 1.000 rs1341759 chr6:26195502 G/A cg16070018 chr6:26224392 HIST1H3E 0.57 6.81 0.35 4.47e-11 Gout;Renal underexcretion gout; LIHC trans rs7726839 0.540 rs4957081 chr5:646418 G/C cg25482853 chr8:67687455 SGK3 0.6 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs79976124 0.797 rs2226266 chr6:66617302 C/T cg07460842 chr6:66804631 NA 0.62 6.18 0.32 1.85e-9 Type 2 diabetes; LIHC cis rs508618 0.638 rs479200 chr1:231543780 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.64 -9.24 -0.45 2.68e-18 Red blood cell count; LIHC cis rs7246657 1.000 rs12709812 chr19:37794850 A/G cg23950597 chr19:37808831 NA 0.52 6.54 0.33 2.2e-10 Coronary artery calcification; LIHC cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg18230493 chr5:56204884 C5orf35 -0.44 -6.11 -0.31 2.74e-9 Initial pursuit acceleration; LIHC cis rs2073499 1.000 rs6776145 chr3:50316119 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.96 -16.56 -0.67 1.22e-45 Schizophrenia; LIHC cis rs10078 1.000 rs10078 chr5:438102 G/T cg08916839 chr5:415575 AHRR 0.5 10.55 0.5 1.06e-22 Fat distribution (HIV); LIHC cis rs2637266 1.000 rs7905033 chr10:78368212 A/C cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC cis rs4766646 0.757 rs4766641 chr12:110301492 T/A cg12870014 chr12:110450643 ANKRD13A 0.36 6.22 0.32 1.42e-9 Metabolite levels (MHPG); LIHC cis rs7582180 0.676 rs11691135 chr2:100934038 C/T cg14675211 chr2:100938903 LONRF2 0.56 8.78 0.43 7.72e-17 Intelligence (multi-trait analysis); LIHC cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg21280719 chr6:42927975 GNMT -0.34 -7.4 -0.37 1.03e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs735396 0.770 rs2264782 chr12:121432603 C/T cg02403541 chr12:121454288 C12orf43 0.46 8.07 0.4 1.23e-14 N-glycan levels; LIHC cis rs9443189 0.570 rs7770824 chr6:76408189 G/A cg01950844 chr6:76311363 SENP6 0.87 10.9 0.51 6.08e-24 Prostate cancer; LIHC cis rs8072100 0.934 rs8067286 chr17:45594590 A/G cg19378624 chr17:45501242 LOC100272146;C17orf57 0.36 5.71 0.3 2.39e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs780096 0.546 rs35073769 chr2:27731376 C/T cg21747090 chr2:27597821 SNX17 -0.41 -5.92 -0.31 7.64e-9 Total body bone mineral density; LIHC cis rs9905704 0.647 rs12940492 chr17:56954655 C/G cg05425664 chr17:57184151 TRIM37 -0.44 -6.18 -0.32 1.82e-9 Testicular germ cell tumor; LIHC cis rs1008375 0.966 rs2010053 chr4:17583806 A/C cg16339924 chr4:17578868 LAP3 0.46 6.27 0.32 1.09e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg20295408 chr7:1910781 MAD1L1 -0.5 -7.18 -0.36 4.24e-12 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs9505454 chr6:8478532 T/G cg07606381 chr6:8435919 SLC35B3 0.79 11.83 0.54 2.7e-27 Motion sickness; LIHC trans rs637571 0.557 rs1204649 chr11:65702776 A/C cg17712092 chr4:129076599 LARP1B 0.76 13.09 0.58 5.31e-32 Eosinophil percentage of white cells; LIHC cis rs1580019 0.563 rs34319173 chr7:32585904 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.12 24.6 0.8 1.17e-77 Cognitive ability; LIHC cis rs7100689 0.725 rs2185425 chr10:82139941 T/C cg00277334 chr10:82204260 NA -0.53 -6.76 -0.34 6.08e-11 Post bronchodilator FEV1; LIHC cis rs7635838 0.617 rs346075 chr3:11294027 T/G cg00170343 chr3:11313890 ATG7 0.6 9.98 0.48 9.08e-21 HDL cholesterol; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg14257396 chr1:107603778 NA -0.37 -6.1 -0.31 2.79e-9 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg03207436 chr5:125937141 PHAX 0.4 6.09 0.31 3.04e-9 Morning vs. evening chronotype; LIHC trans rs6951245 0.554 rs10246354 chr7:1132456 C/T cg13565492 chr6:43139072 SRF -0.86 -7.94 -0.39 2.87e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9534288 0.912 rs4941540 chr13:46604710 C/T cg15192986 chr13:46630673 CPB2 -0.57 -8.69 -0.43 1.56e-16 Blood protein levels; LIHC cis rs4820294 1.000 rs41280035 chr22:38054038 A/G cg26138144 chr22:38071188 LGALS1 0.71 13.26 0.58 1.16e-32 Fat distribution (HIV); LIHC cis rs2273669 0.667 rs12196010 chr6:109302173 C/A cg05315195 chr6:109294784 ARMC2 -0.53 -5.75 -0.3 1.99e-8 Prostate cancer; LIHC cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs11792861 0.926 rs118011482 chr9:111770626 G/C cg13535736 chr9:111863775 C9orf5 -0.4 -6.08 -0.31 3.23e-9 Menarche (age at onset); LIHC cis rs8180040 0.800 rs56250009 chr3:47279497 G/C cg16586182 chr3:47516702 SCAP 0.51 9.01 0.44 1.45e-17 Colorectal cancer; LIHC cis rs12971120 1.000 rs2278162 chr18:72175814 A/G cg26446133 chr18:72167187 CNDP2 -0.79 -14.73 -0.62 2.22e-38 Refractive error; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg14004847 chr7:1930337 MAD1L1 -0.45 -6.58 -0.34 1.77e-10 Bipolar disorder and schizophrenia; LIHC cis rs1691799 0.867 rs2172881 chr12:66766039 C/G cg16791601 chr12:66731901 HELB -0.55 -13.21 -0.58 1.75e-32 White blood cell count (basophil); LIHC cis rs875971 0.660 rs801193 chr7:66030612 A/C cg00343986 chr7:65444356 GUSB -0.4 -6.11 -0.31 2.79e-9 Aortic root size; LIHC cis rs6121246 0.529 rs6058152 chr20:30178107 G/A cg13852791 chr20:30311386 BCL2L1 0.7 6.31 0.32 8.68e-10 Mean corpuscular hemoglobin; LIHC cis rs733592 0.599 rs12819124 chr12:48409054 G/T cg21466736 chr12:48725269 NA -0.34 -5.74 -0.3 2.13e-8 Plateletcrit; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg25970120 chr1:39325951 RRAGC -0.41 -6.07 -0.31 3.45e-9 Body mass index; LIHC cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg06481639 chr22:41940642 POLR3H 0.61 5.72 0.3 2.38e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2050392 0.590 rs685319 chr10:30719331 G/A cg25182066 chr10:30743637 MAP3K8 -0.63 -9.99 -0.48 8.8e-21 Inflammatory bowel disease; LIHC cis rs4638749 0.677 rs998186 chr2:108844237 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs1914816 0.878 rs2456078 chr15:76558870 T/C cg03037974 chr15:76606532 NA -0.61 -6.36 -0.33 6.48e-10 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg05552183 chr6:42928497 GNMT 0.68 10.19 0.48 1.78e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7575217 0.697 rs796067 chr2:101707009 C/T cg23907051 chr2:101730305 TBC1D8 -0.25 -5.8 -0.3 1.51e-8 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; LIHC cis rs7674212 0.570 rs1031804 chr4:104066049 C/T cg16532752 chr4:104119610 CENPE -0.45 -7.07 -0.36 8.87e-12 Type 2 diabetes; LIHC cis rs4927850 0.752 rs7624460 chr3:195748530 C/T cg01181863 chr3:195395398 SDHAP2 -0.63 -8.88 -0.43 3.73e-17 Pancreatic cancer; LIHC cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.28 0.32 1e-9 Schizophrenia; LIHC cis rs12908161 0.960 rs62019463 chr15:85288087 G/A cg17507749 chr15:85114479 UBE2QP1 0.62 7.09 0.36 7.9e-12 Schizophrenia; LIHC trans rs1005277 0.602 rs1740743 chr10:38519222 C/T cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs9309711 0.666 rs6723101 chr2:3484443 T/C cg15506890 chr2:3487001 NA -0.47 -7.55 -0.38 3.9e-13 Neurofibrillary tangles; LIHC cis rs7772486 0.875 rs2814866 chr6:146339414 C/A cg13319975 chr6:146136371 FBXO30 -0.35 -5.84 -0.3 1.23e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4930561 0.714 rs6591335 chr11:67976812 T/C cg04465784 chr11:67976953 SUV420H1 -0.3 -5.75 -0.3 1.97e-8 Breast cancer in childhood cancer survivors;IgG glycosylation; LIHC trans rs4906332 1.000 rs8012623 chr14:103937086 G/A cg17675199 chr6:35436792 RPL10A 0.35 6.88 0.35 2.81e-11 Coronary artery disease; LIHC cis rs9457247 0.765 rs1322077 chr6:167424293 T/C cg12798992 chr6:167411361 FGFR1OP 0.49 7.54 0.38 4.33e-13 Crohn's disease; LIHC cis rs8017423 0.647 rs12883844 chr14:90820519 T/C cg04374321 chr14:90722782 PSMC1 -0.5 -7.39 -0.37 1.12e-12 Mortality in heart failure; LIHC cis rs1355223 0.583 rs2941044 chr11:34867444 A/C cg24088639 chr11:34937564 PDHX;APIP -0.38 -5.98 -0.31 5.48e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1144333 1.000 rs12410724 chr1:76459134 A/G cg03433033 chr1:76189801 ACADM 0.51 7.58 0.38 3.18e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.98 8.73 0.43 1.11e-16 Platelet count; LIHC cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg08392591 chr16:89556376 ANKRD11 0.45 6.8 0.35 4.62e-11 Multiple myeloma (IgH translocation); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04174309 chr11:117102980 RNF214;PCSK7 0.49 6.32 0.32 8.34e-10 Lung function (FEV1/FVC); LIHC cis rs763121 0.814 rs5757212 chr22:39053757 G/C cg06022373 chr22:39101656 GTPBP1 0.75 15.23 0.64 2.5e-40 Menopause (age at onset); LIHC cis rs11628318 0.660 rs35258120 chr14:103058769 G/A cg23461800 chr14:103021989 NA -0.43 -5.96 -0.31 6.39e-9 Platelet count; LIHC cis rs9814567 0.806 rs4074522 chr3:134325626 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 5.73 0.3 2.19e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs16944613 0.588 rs6496697 chr15:91131832 C/T cg26821196 chr15:91095069 CRTC3 -0.45 -7.78 -0.39 8.81e-14 Colorectal cancer; LIHC cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4561483 0.583 rs11645213 chr16:11942924 C/A cg08843971 chr16:11963173 GSPT1 0.37 6.87 0.35 3.11e-11 Testicular germ cell tumor; LIHC cis rs965469 0.895 rs6037595 chr20:3401128 T/G cg25506879 chr20:3388711 C20orf194 -0.51 -6.08 -0.31 3.19e-9 IFN-related cytopenia; LIHC cis rs4654899 0.758 rs12078457 chr1:21397071 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.76 0.3 1.91e-8 Superior frontal gyrus grey matter volume; LIHC cis rs539514 0.690 rs585233 chr13:76317973 A/G cg04757411 chr13:76259545 LMO7 0.45 7.92 0.39 3.41e-14 Type 1 diabetes; LIHC cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg05590025 chr7:65112418 INTS4L2 -0.65 -7.36 -0.37 1.35e-12 Diabetic kidney disease; LIHC cis rs9811920 0.609 rs793460 chr3:99615733 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs8141529 0.632 rs5762803 chr22:29193638 G/C cg02153584 chr22:29168773 CCDC117 0.57 8.62 0.42 2.49e-16 Lymphocyte counts; LIHC cis rs727563 0.638 rs4820443 chr22:42193913 A/G cg06634786 chr22:41940651 POLR3H -0.7 -7.25 -0.36 2.82e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9399135 0.967 rs6915770 chr6:135369214 G/A cg24558204 chr6:135376177 HBS1L 0.44 7.23 0.36 3.16e-12 Red blood cell count; LIHC cis rs506338 0.517 rs12269736 chr11:64471986 T/C cg03263716 chr11:64435066 NRXN2 0.32 6.82 0.35 4.03e-11 Body mass index;Urate levels; LIHC cis rs11122272 0.706 rs2749710 chr1:231535112 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.7 11.08 0.51 1.43e-24 Hemoglobin concentration; LIHC cis rs4699052 0.928 rs2866642 chr4:104213866 T/G cg16532752 chr4:104119610 CENPE -0.4 -6.3 -0.32 9.07e-10 Testicular germ cell tumor; LIHC cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg25364880 chr3:44379878 C3orf23 0.43 6.15 0.32 2.13e-9 Depressive symptoms; LIHC cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.05e-9 Menopause (age at onset); LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg26338869 chr17:61819248 STRADA 0.43 6.15 0.32 2.13e-9 Prudent dietary pattern; LIHC cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg16405210 chr4:1374714 KIAA1530 0.93 16.1 0.66 8.23e-44 Longevity; LIHC cis rs2576037 0.526 rs10853544 chr18:44474194 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.59 0.5 7.35e-23 Personality dimensions; LIHC cis rs17106184 1.000 rs57412341 chr1:51310327 A/G cg07174182 chr1:51127561 FAF1 -0.62 -6.52 -0.33 2.47e-10 Type 2 diabetes; LIHC cis rs743757 1.000 rs2236955 chr3:50429876 G/A cg12708802 chr3:50388878 TUSC4;CYB561D2 0.46 7.11 0.36 6.82e-12 Diastolic blood pressure; LIHC cis rs8056893 0.714 rs4783554 chr16:68384010 A/G cg02226672 chr16:68398533 SMPD3 0.44 6.31 0.32 8.55e-10 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs7772486 0.713 rs1986729 chr6:146194831 G/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.24 -0.32 1.33e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.601 rs9502715 chr6:8455709 C/T cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC cis rs17401966 0.522 rs7368073 chr1:10314962 G/T cg19773385 chr1:10388646 KIF1B -0.34 -6.13 -0.31 2.44e-9 Hepatocellular carcinoma; LIHC cis rs12478296 0.901 rs7420176 chr2:243005277 G/A cg18898632 chr2:242989856 NA -0.47 -6.51 -0.33 2.7e-10 Obesity-related traits; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.9 -0.3 8.51e-9 Menopause (age at onset); LIHC cis rs7909074 1.000 rs7079573 chr10:45400406 G/A cg05187965 chr10:45406764 TMEM72 -0.27 -6.79 -0.34 4.91e-11 Mean corpuscular volume; LIHC cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg19723775 chr5:179050963 HNRNPH1 0.59 9.85 0.47 2.65e-20 Lung cancer; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg24115593 chr5:169010705 CCDC99 -0.55 -6.33 -0.32 7.92e-10 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs4713118 0.662 rs149970 chr6:27980220 C/T cg16479474 chr6:28041457 NA 0.4 6.22 0.32 1.48e-9 Parkinson's disease; LIHC cis rs77861329 1.000 rs9843852 chr3:52132029 C/G cg08692210 chr3:52188851 WDR51A 0.82 8.02 0.4 1.65e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.18 0.55 1.41e-28 Height; LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg08469215 chr1:156261351 TMEM79 0.4 6.55 0.33 2.1e-10 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs1707322 0.758 rs10789474 chr1:46250040 G/T cg03146154 chr1:46216737 IPP 0.52 8.44 0.41 9.43e-16 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg00343986 chr7:65444356 GUSB -0.43 -6.13 -0.31 2.36e-9 Aortic root size; LIHC cis rs77861329 1.000 rs9817653 chr3:52148233 T/G cg08692210 chr3:52188851 WDR51A 0.83 7.85 0.39 5.47e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs1256061 0.533 rs2357479 chr14:64792764 G/T cg23250157 chr14:64679961 SYNE2 0.42 6.2 0.32 1.6e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs5753618 0.561 rs9606830 chr22:31717799 T/G cg22777020 chr22:31556080 RNF185 0.56 6.41 0.33 4.78e-10 Colorectal cancer; LIHC cis rs561341 1.000 rs4795670 chr17:30244839 T/C cg13647721 chr17:30228624 UTP6 0.76 7.38 0.37 1.17e-12 Hip circumference adjusted for BMI; LIHC cis rs3008870 0.755 rs2208577 chr1:67513574 A/C cg02640540 chr1:67518911 SLC35D1 0.66 12.8 0.57 6.17e-31 Lymphocyte percentage of white cells; LIHC cis rs12142240 0.698 rs45449893 chr1:46859024 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC cis rs1003719 0.788 rs4411798 chr21:38453183 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.72 11.15 0.52 7.79e-25 Eye color traits; LIHC cis rs4853012 0.941 rs2421752 chr2:74341615 A/G cg05890377 chr2:74357713 NA 0.64 12.97 0.57 1.43e-31 Gestational age at birth (maternal effect); LIHC cis rs875971 0.545 rs6970498 chr7:65740895 A/G cg11764359 chr7:65958608 NA 0.57 7.88 0.39 4.45e-14 Aortic root size; LIHC cis rs12893668 0.703 rs55751606 chr14:104028806 G/A cg19000871 chr14:103996768 TRMT61A -0.44 -7.24 -0.36 2.96e-12 Reticulocyte count; LIHC cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.58 0.38 3.36e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9517313 0.592 rs11069311 chr13:99202101 G/T cg20487152 chr13:99095054 FARP1 -0.37 -6.17 -0.32 1.96e-9 Neuroticism; LIHC cis rs35306767 0.903 rs12244355 chr10:944465 T/C cg26597838 chr10:835615 NA 1.13 13.99 0.6 1.79e-35 Eosinophil percentage of granulocytes; LIHC cis rs6060717 0.610 rs2794382 chr20:34613651 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -8.06 -0.4 1.3e-14 Hip circumference adjusted for BMI; LIHC cis rs12824058 0.799 rs4759656 chr12:130815804 G/A cg24229701 chr12:130821962 PIWIL1 0.44 6.77 0.34 5.55e-11 Menopause (age at onset); LIHC cis rs10420951 0.617 rs75245298 chr19:18581227 T/C cg10790698 chr19:18539756 SSBP4 -0.42 -5.83 -0.3 1.25e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs748404 0.631 rs6493083 chr15:43637985 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.53 9.5 0.46 3.88e-19 Lung cancer; LIHC cis rs611744 0.967 rs650437 chr8:109210927 T/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC trans rs4843747 0.671 rs9933794 chr16:88116981 T/C cg26811252 chr16:29126840 RRN3P2 0.42 6.6 0.34 1.58e-10 Menopause (age at onset); LIHC trans rs2727020 0.538 rs11040373 chr11:49461791 T/C cg15704280 chr7:45808275 SEPT13 -0.62 -10.17 -0.48 2.14e-21 Coronary artery disease; LIHC cis rs926392 0.547 rs8118808 chr20:37674996 C/G cg16355469 chr20:37678765 NA 0.53 8.44 0.42 8.86e-16 Dialysis-related mortality; LIHC cis rs2070433 0.851 rs10854484 chr21:47926702 T/C cg12379764 chr21:47803548 PCNT 0.6 8.76 0.43 9.25e-17 Lymphocyte counts; LIHC cis rs116095464 0.558 rs7730700 chr5:264713 G/A cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs8017423 0.904 rs12433417 chr14:90804028 A/G cg14092571 chr14:90743983 NA 0.42 6.52 0.33 2.52e-10 Mortality in heart failure; LIHC cis rs9513627 0.834 rs73556197 chr13:100128479 A/G cg25919922 chr13:100150906 NA -0.77 -6.89 -0.35 2.74e-11 Obesity-related traits; LIHC cis rs9473924 0.542 rs56240592 chr6:50815514 T/A cg14470998 chr6:50812995 TFAP2B 0.98 11.12 0.52 9.6e-25 Body mass index; LIHC cis rs1801251 0.778 rs709934 chr2:233733352 A/G cg08000102 chr2:233561755 GIGYF2 -0.71 -10.5 -0.49 1.53e-22 Coronary artery disease; LIHC cis rs2295359 1.000 rs10889661 chr1:67625309 T/A cg12940439 chr1:67600707 NA 0.4 7.18 0.36 4.42e-12 Psoriasis; LIHC trans rs6934970 1.000 rs12196593 chr6:113022033 T/A cg09308777 chr6:169852575 NA 0.6 6.21 0.32 1.5e-9 Bipolar disorder (body mass index interaction); LIHC cis rs9388451 1.000 rs9388451 chr6:126090377 A/G cg06289844 chr6:126071538 HEY2 0.36 6.15 0.32 2.2e-9 Brugada syndrome; LIHC cis rs11734570 0.581 rs73811715 chr4:38590569 A/C cg18361445 chr4:38666374 KLF3;FLJ13197 0.53 7.26 0.37 2.6e-12 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7592578 0.766 rs12472081 chr2:191398545 G/A cg10560079 chr2:191398806 TMEM194B -0.87 -12.17 -0.55 1.44e-28 Diastolic blood pressure; LIHC cis rs1000083 0.748 rs4413553 chr5:96621221 A/G ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs7772486 0.686 rs9390349 chr6:146054430 T/G cg23711669 chr6:146136114 FBXO30 -0.62 -11.33 -0.52 1.76e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.932 rs62248599 chr3:47516728 G/A cg27129171 chr3:47204927 SETD2 -0.57 -9.78 -0.47 4.48e-20 Colorectal cancer; LIHC cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg20011983 chr2:74347215 NA -0.39 -5.86 -0.3 1.08e-8 Gestational age at birth (maternal effect); LIHC cis rs4242434 0.698 rs10104039 chr8:22538384 A/G cg03733263 chr8:22462867 KIAA1967 -0.6 -10.51 -0.49 1.41e-22 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs1691799 0.899 rs4762091 chr12:66747863 A/G cg16791601 chr12:66731901 HELB -0.56 -13.91 -0.6 3.75e-35 White blood cell count (basophil); LIHC cis rs858239 0.600 rs7784929 chr7:23124277 T/C cg23682824 chr7:23144976 KLHL7 0.43 6.45 0.33 3.91e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs12644436 0.576 rs13151968 chr4:88784874 T/C cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs919433 0.783 rs788007 chr2:198233676 T/G cg10820045 chr2:198174542 NA 0.56 8.88 0.43 3.78e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7534824 0.625 rs61780288 chr1:101389945 T/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 7.07 0.36 8.96e-12 Refractive astigmatism; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.17 -0.32 1.91e-9 Total body bone mineral density; LIHC cis rs4908768 0.501 rs11121201 chr1:8632791 A/T cg20416874 chr1:8611966 RERE -0.69 -14.54 -0.62 1.22e-37 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.56 7.81 0.39 7.04e-14 Intelligence (multi-trait analysis); LIHC cis rs7091068 0.671 rs517785 chr10:95403973 G/A cg20715218 chr10:95462985 C10orf4 -0.62 -6.81 -0.35 4.3e-11 Urinary tract infection frequency; LIHC cis rs1790761 0.692 rs10444362 chr11:67333090 G/A cg01069141 chr11:67398826 TBX10;NUDT8 0.37 6.51 0.33 2.68e-10 Mean corpuscular volume; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg06850467 chr2:110371607 SEPT10;ANKRD57 0.36 6.15 0.32 2.14e-9 Electroencephalogram traits; LIHC cis rs2607426 0.579 rs2644917 chr19:41287007 G/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.54 -6.18 -0.32 1.77e-9 Blood protein levels; LIHC cis rs9583531 0.657 rs9521915 chr13:111384528 C/T cg24331049 chr13:111365604 ING1 0.78 12.96 0.57 1.55e-31 Coronary artery disease; LIHC cis rs7312933 0.558 rs11181463 chr12:42763636 C/T cg17420585 chr12:42539391 GXYLT1 -0.37 -6.08 -0.31 3.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg22395253 chr7:104941898 SRPK2 0.44 6.38 0.33 5.7e-10 Immature fraction of reticulocytes; LIHC cis rs798554 0.680 rs2533889 chr7:2900309 G/C cg13628971 chr7:2884303 GNA12 0.57 8.98 0.44 1.85e-17 Height; LIHC cis rs8180040 0.701 rs11130111 chr3:47009805 C/T cg02527881 chr3:46936655 PTH1R -0.35 -7.16 -0.36 5.02e-12 Colorectal cancer; LIHC cis rs7772486 0.754 rs6910790 chr6:146255330 G/A cg13319975 chr6:146136371 FBXO30 0.35 5.77 0.3 1.82e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs138880 0.542 rs9616210 chr22:50317346 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.82 -7.26 -0.37 2.7e-12 Schizophrenia; LIHC cis rs12079745 0.793 rs12071630 chr1:169421023 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.75 -6.78 -0.34 5.28e-11 QT interval; LIHC cis rs1577917 0.958 rs2225754 chr6:86449698 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.41 -0.37 9.78e-13 Response to antipsychotic treatment; LIHC cis rs79839061 0.610 rs2279181 chr4:882643 A/G cg07828340 chr4:882639 GAK -0.79 -7.0 -0.35 1.34e-11 Intelligence (multi-trait analysis); LIHC cis rs2439831 0.867 rs2243434 chr15:43689867 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.84 0.51 9.48e-24 Lung cancer in ever smokers; LIHC cis rs3780378 0.967 rs7043371 chr9:5040203 T/A cg02405213 chr9:5042618 JAK2 -0.56 -9.87 -0.47 2.18e-20 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs3806843 0.735 rs801183 chr5:140091115 C/T cg26395211 chr5:140044315 WDR55 -0.4 -5.96 -0.31 6.39e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9911578 0.803 rs8069033 chr17:57131581 T/A cg12560992 chr17:57184187 TRIM37 -0.97 -17.95 -0.7 3.2e-51 Intelligence (multi-trait analysis); LIHC cis rs10197940 0.901 rs2290367 chr2:152266731 T/A cg19508488 chr2:152266495 RIF1 0.74 12.6 0.56 3.68e-30 Lung cancer; LIHC cis rs72627509 0.587 rs17087401 chr4:57901155 G/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.55 -7.29 -0.37 2.23e-12 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs986417 1.000 rs1254265 chr14:60840478 T/C cg27398547 chr14:60952738 C14orf39 -0.79 -9.04 -0.44 1.22e-17 Gut microbiota (bacterial taxa); LIHC cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg10360323 chr17:41437877 NA 0.41 6.09 0.31 3.1e-9 Menopause (age at onset); LIHC trans rs2243480 1.000 rs6959002 chr7:65650496 A/G cg10756647 chr7:56101905 PSPH -1.07 -13.17 -0.58 2.44e-32 Diabetic kidney disease; LIHC cis rs6840360 0.554 rs10222838 chr4:152690099 T/C cg22705602 chr4:152727874 NA -0.4 -8.47 -0.42 7.54e-16 Intelligence (multi-trait analysis); LIHC cis rs860295 0.812 rs10908481 chr1:155713650 T/G cg02153340 chr1:155202674 NA -0.35 -6.3 -0.32 9.36e-10 Body mass index; LIHC cis rs595982 0.527 rs17206707 chr19:49361441 A/C cg21252483 chr19:49399788 TULP2 -0.84 -9.78 -0.47 4.41e-20 Red cell distribution width; LIHC cis rs2404602 0.692 rs72738889 chr15:76992063 G/A cg23625390 chr15:77176239 SCAPER 0.36 5.93 0.31 7.52e-9 Blood metabolite levels; LIHC cis rs4970966 0.904 rs12131809 chr1:150544640 C/T cg18016565 chr1:150552671 MCL1 -0.43 -6.26 -0.32 1.14e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs9902453 0.845 rs58575982 chr17:28221776 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.03e-27 Coffee consumption (cups per day); LIHC cis rs4132509 1.000 rs57824597 chr1:243930399 C/T cg21452805 chr1:244014465 NA 0.42 5.75 0.3 1.96e-8 RR interval (heart rate); LIHC cis rs4629710 0.645 rs35561719 chr6:131551244 G/A cg12606694 chr6:131520996 AKAP7 0.64 7.39 0.37 1.14e-12 Multiple myeloma (IgH translocation); LIHC cis rs769267 0.931 rs2965193 chr19:19454828 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -9.86 -0.47 2.47e-20 Tonsillectomy; LIHC cis rs9733 0.818 rs4970924 chr1:150633079 A/G cg17724175 chr1:150552817 MCL1 -0.37 -7.77 -0.39 9.35e-14 Tonsillectomy; LIHC cis rs2016586 0.561 rs5755929 chr22:36118302 G/A cg26342177 chr22:36113512 APOL5 -0.35 -5.82 -0.3 1.32e-8 Body mass index; LIHC cis rs12926788 0.542 rs11862971 chr16:24767574 C/A cg04756594 chr16:24857601 SLC5A11 0.61 9.31 0.45 1.58e-18 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1707322 0.827 rs6694302 chr1:46245645 A/T cg06784218 chr1:46089804 CCDC17 0.39 7.03 0.36 1.16e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg10802521 chr3:52805072 NEK4 -0.45 -7.73 -0.39 1.2e-13 Bipolar disorder; LIHC cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs757081 0.667 rs12577418 chr11:17101554 C/G cg15432903 chr11:17409602 KCNJ11 -0.41 -5.74 -0.3 2.04e-8 Systolic blood pressure; LIHC cis rs941408 0.515 rs7253128 chr19:2776982 C/T cg06609049 chr19:2785107 THOP1 0.78 13.12 0.58 3.8e-32 Total cholesterol levels; LIHC trans rs11098499 0.863 rs7657849 chr4:120455494 T/C cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs12701220 0.553 rs7782024 chr7:1157502 G/T cg18765753 chr7:1198926 ZFAND2A -0.44 -6.18 -0.32 1.81e-9 Bronchopulmonary dysplasia; LIHC cis rs1707322 1.000 rs10890370 chr1:46389217 C/T cg06784218 chr1:46089804 CCDC17 0.36 6.34 0.32 7.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2439831 0.850 rs16977798 chr15:44151948 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.66 0.34 1.11e-10 Lung cancer in ever smokers; LIHC cis rs11031096 0.711 rs4910891 chr11:4153408 A/G cg18678763 chr11:4115507 RRM1 -0.58 -8.66 -0.42 1.92e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs3936840 0.548 rs1190545 chr14:102904179 G/C cg10241871 chr14:102965420 TECPR2 0.43 6.77 0.34 5.46e-11 Plateletcrit; LIHC cis rs7589728 0.858 rs1914734 chr2:88529509 T/C cg04511125 chr2:88470314 THNSL2 0.69 6.8 0.35 4.72e-11 Plasma clusterin levels; LIHC cis rs9611565 0.500 rs2011053 chr22:42121278 G/A cg06634786 chr22:41940651 POLR3H 0.57 6.26 0.32 1.12e-9 Vitiligo; LIHC cis rs8027181 1.000 rs8030477 chr15:73085815 C/T cg25632853 chr15:73088954 NA 0.39 6.47 0.33 3.38e-10 Triglyceride levels; LIHC cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg00656387 chr3:40428638 ENTPD3 -0.43 -7.43 -0.37 8.99e-13 Renal cell carcinoma; LIHC cis rs7502590 1.000 rs7502590 chr17:79082081 A/G cg02064366 chr17:79045526 BAIAP2 0.53 6.25 0.32 1.19e-9 Neuroticism; LIHC trans rs116095464 0.558 rs10058428 chr5:235608 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.11 0.36 7.03e-12 Breast cancer; LIHC cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg05590025 chr7:65112418 INTS4L2 -0.65 -7.16 -0.36 4.88e-12 Diabetic kidney disease; LIHC cis rs7584330 0.554 rs7558685 chr2:238434943 A/G cg08992911 chr2:238395768 MLPH 0.49 5.95 0.31 6.48e-9 Prostate cancer; LIHC cis rs2412488 0.927 rs10021541 chr4:54286095 G/A cg22241045 chr4:54363911 LNX1 -0.42 -6.87 -0.35 3.02e-11 DNA methylation (variation); LIHC cis rs1448094 0.512 rs11117060 chr12:86250788 G/T cg02569458 chr12:86230093 RASSF9 -0.46 -6.12 -0.31 2.5e-9 Major depressive disorder; LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg21448741 chr8:58168803 NA 0.35 6.45 0.33 3.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg09033563 chr22:24373618 LOC391322 0.44 6.35 0.32 6.88e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17685 0.753 rs10262501 chr7:75668172 G/A cg01364799 chr7:75623366 TMEM120A 0.52 7.84 0.39 5.66e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2346177 0.576 rs1530621 chr2:46688688 T/C cg02822958 chr2:46747628 ATP6V1E2 0.48 7.04 0.36 1.08e-11 HDL cholesterol; LIHC cis rs7238033 0.624 rs9946998 chr18:43312822 C/T cg20610511 chr18:43302872 SLC14A1 0.37 6.24 0.32 1.31e-9 Bladder cancer; LIHC cis rs10791097 0.694 rs7106973 chr11:130758113 G/A cg12179176 chr11:130786555 SNX19 0.87 14.28 0.61 1.25e-36 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg10560079 chr2:191398806 TMEM194B 0.51 7.93 0.39 3.14e-14 Pulse pressure; LIHC cis rs4819052 0.851 rs9974628 chr21:46672647 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.4 0.52 1.01e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7520050 0.931 rs6697557 chr1:46307809 G/A cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs3015497 0.789 rs11621971 chr14:51124527 C/T cg09863266 chr14:51125203 SAV1 0.41 6.58 0.34 1.81e-10 Mean platelet volume; LIHC cis rs7589728 0.748 rs3791357 chr2:88478664 C/T cg07952391 chr2:88470173 THNSL2 0.76 7.15 0.36 5.22e-12 Plasma clusterin levels; LIHC cis rs6598955 0.670 rs11247892 chr1:26592727 A/G cg04990556 chr1:26633338 UBXN11 -0.62 -10.23 -0.48 1.35e-21 Obesity-related traits; LIHC cis rs17253792 0.822 rs74412558 chr14:56054311 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.15e-10 Putamen volume; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg17042098 chr1:61519631 NA 0.44 6.84 0.35 3.66e-11 Bilirubin levels; LIHC cis rs11690935 0.851 rs10201430 chr2:172813241 T/C cg13550731 chr2:172543902 DYNC1I2 -0.44 -7.41 -0.37 1.01e-12 Schizophrenia; LIHC cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg21877656 chr19:58662188 ZNF329 1.07 8.24 0.41 3.82e-15 Cholesterol, total; LIHC cis rs4631830 0.832 rs2611513 chr10:51515457 A/G cg20129853 chr10:51489980 NA 0.39 8.81 0.43 6.29e-17 Prostate-specific antigen levels; LIHC cis rs6062302 0.548 rs4809310 chr20:62228745 G/A cg06363034 chr20:62225388 GMEB2 -0.45 -7.6 -0.38 2.8e-13 Glioblastoma; LIHC cis rs5769707 0.967 rs8141807 chr22:50043738 C/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.59 -0.42 3.06e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7223966 1.000 rs11542436 chr17:61778689 A/C cg05941027 chr17:61774174 LIMD2 0.32 6.61 0.34 1.52e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7224685 0.569 rs12947597 chr17:3999199 A/G cg09597638 chr17:3907349 NA -0.46 -6.41 -0.33 4.88e-10 Type 2 diabetes; LIHC cis rs7208859 0.623 rs55638872 chr17:29149552 G/C cg13385521 chr17:29058706 SUZ12P 0.83 8.12 0.4 8.57e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12497850 0.931 rs9311433 chr3:48863835 T/C cg06212747 chr3:49208901 KLHDC8B 0.55 7.12 0.36 6.57e-12 Parkinson's disease; LIHC cis rs4853012 0.887 rs77148265 chr2:74339519 C/T cg01017244 chr2:74357527 NA 0.64 11.16 0.52 7.27e-25 Gestational age at birth (maternal effect); LIHC cis rs2016586 0.894 rs4821432 chr22:36100896 G/C cg26342177 chr22:36113512 APOL5 -0.38 -6.24 -0.32 1.3e-9 Body mass index; LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg06420487 chr17:61919686 SMARCD2 0.43 5.79 0.3 1.6e-8 Height; LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg12516959 chr21:47718080 NA -0.39 -6.18 -0.32 1.77e-9 Testicular germ cell tumor; LIHC cis rs7122539 0.646 rs682842 chr11:66568943 A/G cg24851651 chr11:66362959 CCS -0.35 -6.01 -0.31 4.63e-9 HIV-1 susceptibility; LIHC cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.49e-29 Menopause (age at onset); LIHC cis rs75908454 1.000 rs79951072 chr6:169830051 C/T cg19338460 chr6:170058176 WDR27 -0.86 -7.77 -0.39 9.33e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs1790761 0.667 rs4147581 chr11:67351585 C/G cg21734168 chr11:67353974 GSTP1 -0.28 -6.85 -0.35 3.37e-11 Mean corpuscular volume; LIHC cis rs34779708 0.966 rs4934725 chr10:35398236 T/C cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9902453 0.740 rs2729446 chr17:28102499 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs6089829 0.962 rs6122352 chr20:61668284 T/C cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.73e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg11301795 chr4:187892539 NA -0.26 -6.88 -0.35 2.9100000000000002e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg08888203 chr3:10149979 C3orf24 0.52 6.25 0.32 1.25e-9 Alzheimer's disease; LIHC cis rs10484885 0.878 rs111664889 chr6:90566427 G/T cg13799429 chr6:90582589 CASP8AP2 -0.69 -6.54 -0.33 2.29e-10 QRS interval (sulfonylurea treatment interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03239638 chr21:37529510 NA -0.44 -6.14 -0.32 2.29e-9 Cognitive function; LIHC cis rs11971779 0.648 rs9642121 chr7:139092621 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs2075371 0.932 rs11766132 chr7:133993062 T/C cg20476274 chr7:133979776 SLC35B4 0.71 9.5 0.46 3.64e-19 Mean platelet volume; LIHC cis rs763121 0.853 rs2235230 chr22:39124467 A/G cg06022373 chr22:39101656 GTPBP1 -0.64 -10.84 -0.51 1.02e-23 Menopause (age at onset); LIHC cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC cis rs9549367 0.789 rs6577034 chr13:113879900 T/C cg18105134 chr13:113819100 PROZ -0.59 -10.36 -0.49 4.57e-22 Platelet distribution width; LIHC cis rs4906332 1.000 rs1951389 chr14:103898525 G/C cg04998671 chr14:104000505 TRMT61A -0.46 -6.32 -0.32 7.99e-10 Coronary artery disease; LIHC cis rs56104184 0.723 rs73063515 chr19:49407715 C/T cg21252483 chr19:49399788 TULP2 -0.98 -11.29 -0.52 2.41e-25 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs1814175 0.935 rs10839329 chr11:49694206 G/A cg03929089 chr4:120376271 NA -0.89 -17.31 -0.68 1.19e-48 Height; LIHC cis rs6967414 0.605 rs7786706 chr7:6747267 C/T cg00387323 chr7:6746715 ZNF12 0.52 6.05 0.31 3.81e-9 Hematocrit;Hemoglobin concentration; LIHC cis rs9902453 0.904 rs12939344 chr17:28328819 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -13.42 -0.59 2.69e-33 Coffee consumption (cups per day); LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg12016809 chr21:47604291 C21orf56 -0.43 -6.44 -0.33 4.17e-10 Testicular germ cell tumor; LIHC cis rs7582180 0.629 rs11686842 chr2:100956139 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.58 0.42 3.3e-16 Intelligence (multi-trait analysis); LIHC trans rs2832077 0.527 rs2738953 chr21:30238363 G/C cg14791747 chr16:20752902 THUMPD1 -0.69 -10.94 -0.51 4.22e-24 Cognitive test performance; LIHC cis rs6456156 0.586 rs2001115 chr6:167486218 A/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.51 -0.42 5.66e-16 Primary biliary cholangitis; LIHC cis rs1443512 0.812 rs2078098 chr12:54337527 C/A cg25024717 chr12:54324583 NA -0.31 -6.16 -0.32 2.03e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg12310025 chr6:25882481 NA 0.48 6.81 0.35 4.28e-11 Blood metabolite levels; LIHC cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.42 0.45 6.79e-19 Platelet count; LIHC cis rs7903847 0.667 rs7096801 chr10:99140969 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7927592 0.701 rs12226585 chr11:68257861 A/T cg01657329 chr11:68192670 LRP5 0.51 7.46 0.37 7.02e-13 Total body bone mineral density; LIHC cis rs7520050 0.966 rs11211208 chr1:46334256 A/C cg03146154 chr1:46216737 IPP -0.39 -6.41 -0.33 4.79e-10 Red blood cell count;Reticulocyte count; LIHC cis rs9649465 0.967 rs6966470 chr7:123299855 C/T cg03229431 chr7:123269106 ASB15 0.36 7.56 0.38 3.81e-13 Migraine; LIHC cis rs3099143 1.000 rs3099138 chr15:77115524 G/A cg21673338 chr15:77095150 SCAPER -0.51 -7.55 -0.38 4.02e-13 Recalcitrant atopic dermatitis; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg04243181 chr16:15951195 MYH11 -0.35 -6.12 -0.31 2.58e-9 Immature fraction of reticulocytes; LIHC cis rs56235845 0.694 rs12055081 chr5:176757191 C/T cg06060754 chr5:176797920 RGS14 0.48 6.68 0.34 9.95e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg21724239 chr8:58056113 NA 0.58 7.47 0.37 6.87e-13 Developmental language disorder (linguistic errors); LIHC cis rs6951245 0.554 rs75075857 chr7:1140298 C/T cg22907277 chr7:1156413 C7orf50 0.85 8.09 0.4 1.04e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2073499 1.000 rs3806708 chr3:50306249 T/C cg03645007 chr3:50255295 SLC38A3 0.52 6.91 0.35 2.42e-11 Schizophrenia; LIHC cis rs1801251 1.000 rs12474040 chr2:233615345 T/G cg25237894 chr2:233734115 C2orf82 0.57 11.2 0.52 5.05e-25 Coronary artery disease; LIHC cis rs6089829 0.962 rs2314130 chr20:61665129 G/T cg08564027 chr20:61660810 NA 0.4 7.62 0.38 2.52e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs12701220 0.817 rs7798459 chr7:1087965 C/T cg16145915 chr7:1198662 ZFAND2A -0.29 -5.99 -0.31 5.36e-9 Bronchopulmonary dysplasia; LIHC cis rs6429082 0.783 rs291365 chr1:235688043 A/G cg26050004 chr1:235667680 B3GALNT2 0.48 7.76 0.39 1.01e-13 Adiposity; LIHC cis rs4820294 0.669 rs7287358 chr22:38054403 A/G cg00292662 chr22:38071168 LGALS1 0.39 6.63 0.34 1.35e-10 Fat distribution (HIV); LIHC cis rs1055129 0.560 rs2608880 chr17:73938957 C/T cg08125733 chr17:73851984 WBP2 0.56 8.72 0.43 1.21e-16 White matter hyperintensity burden; LIHC cis rs11758351 0.660 rs1997768 chr6:26217728 C/T cg16070018 chr6:26224392 HIST1H3E -0.57 -7.12 -0.36 6.51e-12 Gout;Renal underexcretion gout; LIHC cis rs11148252 0.774 rs6561666 chr13:52930045 A/G cg00495681 chr13:53174319 NA 0.38 6.28 0.32 1.06e-9 Lewy body disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19701416 chr10:28592092 NA 0.43 7.1 0.36 7.28e-12 Cognitive function; LIHC cis rs8053891 0.673 rs35338546 chr16:72022156 C/T cg01557791 chr16:72042693 DHODH -0.45 -6.64 -0.34 1.2e-10 Coronary artery disease; LIHC cis rs9640161 0.711 rs60268791 chr7:150023800 G/T cg17279839 chr7:150038598 RARRES2 0.5 10.53 0.49 1.2e-22 Blood protein levels;Circulating chemerin levels; LIHC cis rs875971 0.545 rs66594357 chr7:65792784 G/A cg11764359 chr7:65958608 NA 0.58 8.16 0.4 6.31e-15 Aortic root size; LIHC cis rs362296 0.698 rs362283 chr4:3259558 T/C cg06533319 chr4:3265114 C4orf44 0.33 5.92 0.3 7.81e-9 Parental longevity (mother's age at death); LIHC trans rs561341 0.941 rs2428336 chr17:30290577 T/C cg20587970 chr11:113659929 NA -1.22 -10.2 -0.48 1.65e-21 Hip circumference adjusted for BMI; LIHC cis rs2302190 0.882 rs3744111 chr17:56607959 G/A cg12560992 chr17:57184187 TRIM37 0.69 8.88 0.43 3.9e-17 Vitamin D levels; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs801193 0.569 rs881285 chr7:66119420 A/G cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs7116495 1.000 rs541022 chr11:71783056 G/A cg26138937 chr11:71823887 C11orf51 -0.7 -6.95 -0.35 1.85e-11 Severe influenza A (H1N1) infection; LIHC cis rs7937682 0.921 rs688354 chr11:111438762 A/G cg09085632 chr11:111637200 PPP2R1B -0.84 -9.85 -0.47 2.51e-20 Primary sclerosing cholangitis; LIHC cis rs7904368 0.568 rs7075036 chr10:16864810 C/T cg23933602 chr10:16859644 RSU1 0.58 10.36 0.49 4.68e-22 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs6977660 0.714 rs728156 chr7:19826309 G/C cg07541023 chr7:19748670 TWISTNB 0.41 6.09 0.31 3.03e-9 Thyroid stimulating hormone; LIHC cis rs4563143 0.514 rs73029079 chr19:29294903 A/G cg04546413 chr19:29218101 NA 0.5 8.58 0.42 3.41e-16 Methadone dose in opioid dependence; LIHC cis rs734999 0.588 rs3748819 chr1:2524966 C/T cg18854424 chr1:2615690 NA 0.34 7.51 0.38 5.22e-13 Ulcerative colitis; LIHC cis rs9303401 0.704 rs740605 chr17:56604811 C/T cg12560992 chr17:57184187 TRIM37 0.79 12.79 0.57 6.86e-31 Cognitive test performance; LIHC cis rs919433 0.680 rs4685 chr2:198257795 C/T cg03934865 chr2:198174659 NA -0.53 -8.06 -0.4 1.29e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs3213545 0.700 rs10849829 chr12:121470256 A/G cg01148741 chr2:96811453 DUSP2 0.38 6.12 0.31 2.51e-9 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs2191566 0.664 rs7251083 chr19:44551866 G/T cg20607764 chr19:44506953 ZNF230 -0.37 -6.25 -0.32 1.21e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs875971 0.508 rs10242423 chr7:66059175 A/G cg18876405 chr7:65276391 NA -0.41 -7.38 -0.37 1.18e-12 Aortic root size; LIHC cis rs6988636 1.000 rs16898084 chr8:124190377 A/T cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs7582180 0.627 rs6749018 chr2:101001859 G/T cg14675211 chr2:100938903 LONRF2 0.55 8.37 0.41 1.54e-15 Intelligence (multi-trait analysis); LIHC cis rs8062405 0.688 rs3924376 chr16:28925978 T/C cg07451762 chr16:28383216 NA -0.36 -6.36 -0.33 6.5e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9612 0.948 rs12609587 chr19:44268654 T/C cg08581076 chr19:44259116 C19orf61 0.61 7.49 0.38 6.11e-13 Exhaled nitric oxide output; LIHC cis rs12586317 0.547 rs74243586 chr14:35477325 C/T cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.03e-32 Psoriasis; LIHC cis rs2228479 0.850 rs12596934 chr16:89841605 T/G cg04013166 chr16:89971882 TCF25 0.53 6.67 0.34 1.04e-10 Skin colour saturation; LIHC cis rs992157 0.730 rs2891078 chr2:219184432 C/T cg00012203 chr2:219082015 ARPC2 0.75 10.52 0.49 1.33e-22 Colorectal cancer; LIHC cis rs2576037 0.583 rs644731 chr18:44426877 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -7.09 -0.36 7.75e-12 Personality dimensions; LIHC cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.11 0.52 1.04e-24 Platelet count; LIHC cis rs2576037 0.507 rs2571019 chr18:44585287 A/T cg19077165 chr18:44547161 KATNAL2 0.47 7.11 0.36 6.62e-12 Personality dimensions; LIHC cis rs4409675 0.576 rs6660899 chr1:28214281 G/C cg23691781 chr1:28212827 C1orf38 0.32 7.67 0.38 1.81e-13 Corneal astigmatism; LIHC cis rs8141529 0.732 rs2347447 chr22:29179739 C/A cg02153584 chr22:29168773 CCDC117 0.56 9.15 0.44 5.27e-18 Lymphocyte counts; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24136288 chr17:43183150 NMT1 0.44 6.6 0.34 1.57e-10 Longevity; LIHC trans rs9929218 0.529 rs2296404 chr16:68729525 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.87 19.53 0.73 1.31e-57 Colorectal cancer; LIHC cis rs9733 0.621 rs12746899 chr1:150579678 A/T cg13175981 chr1:150552382 MCL1 0.64 9.97 0.47 1.04e-20 Tonsillectomy; LIHC cis rs1552244 0.882 rs9812006 chr3:10022658 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.68 -10.74 -0.5 2.2e-23 Alzheimer's disease; LIHC cis rs1799949 0.965 rs2236762 chr17:41226675 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.75 0.3 1.93e-8 Menopause (age at onset); LIHC cis rs1144333 1.000 rs76192904 chr1:76359995 C/T cg10523679 chr1:76189770 ACADM 0.46 6.69 0.34 9.02e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs1707322 0.682 rs10890334 chr1:46100378 A/T cg06784218 chr1:46089804 CCDC17 0.42 7.67 0.38 1.79e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs614226 1.000 rs1167727 chr12:120965508 C/A cg01236616 chr12:121019343 POP5 1.25 19.27 0.72 1.53e-56 Type 1 diabetes nephropathy; LIHC cis rs7107174 0.901 rs2912 chr11:77926292 G/A cg02023728 chr11:77925099 USP35 0.52 9.68 0.46 9.28e-20 Testicular germ cell tumor; LIHC cis rs17376456 0.825 rs10052662 chr5:93271385 A/G cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg10150615 chr22:24372951 LOC391322 -0.46 -6.54 -0.33 2.3e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1775715 0.870 rs1775731 chr10:32253512 A/G cg14930904 chr10:32216787 ARHGAP12 0.4 7.02 0.35 1.21e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9303280 0.806 rs36038753 chr17:38035370 G/T cg11212589 chr17:38028394 ZPBP2 0.35 7.09 0.36 7.92e-12 Self-reported allergy; LIHC cis rs798502 0.522 rs7790322 chr7:2830498 C/T cg19717773 chr7:2847554 GNA12 -0.41 -7.6 -0.38 2.81e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Inflammatory bowel disease;Waist circumference adjusted for BMI in non-smokers;Ulcerative colitis;Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg06634786 chr22:41940651 POLR3H -0.75 -8.53 -0.42 4.65e-16 Vitiligo; LIHC cis rs11628318 0.660 rs8009475 chr14:103058608 A/G cg23461800 chr14:103021989 NA -0.45 -6.16 -0.32 2.03e-9 Platelet count; LIHC cis rs611744 0.752 rs609197 chr8:109234035 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs7619427 0.544 rs9872047 chr3:43991630 C/T cg24966902 chr3:44043705 NA 0.44 6.67 0.34 1.03e-10 Schizophrenia; LIHC cis rs2066819 1.000 rs2066819 chr12:56750204 C/T cg26734620 chr12:56694298 CS 1.21 10.14 0.48 2.67e-21 Psoriasis vulgaris; LIHC cis rs6701037 1.000 rs6683533 chr1:175125440 G/A cg17845761 chr1:175162550 KIAA0040 -0.35 -5.81 -0.3 1.45e-8 Alcohol dependence; LIHC cis rs7903847 0.642 rs10786344 chr10:99165975 T/C cg06359132 chr10:99160096 RRP12 -0.37 -5.93 -0.31 7.28e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs4728302 0.838 rs7798804 chr7:133584085 C/T cg10665199 chr7:133106180 EXOC4 0.36 6.28 0.32 1.04e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs6754311 0.597 rs2278544 chr2:136546110 A/G cg25344623 chr2:136566232 LCT 0.39 7.26 0.37 2.66e-12 Mosquito bite size; LIHC cis rs4650994 0.517 rs2761473 chr1:178609758 A/C cg05350800 chr1:178550844 NA -0.28 -6.02 -0.31 4.6e-9 HDL cholesterol levels;HDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26949087 chr2:26467503 HADHB;HADHA 0.5 6.62 0.34 1.42e-10 Lung function (FEV1/FVC); LIHC cis rs11190604 0.697 rs4559619 chr10:102199884 C/T cg07080220 chr10:102295463 HIF1AN -0.47 -6.85 -0.35 3.52e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.47e-18 Bipolar disorder; LIHC cis rs3768617 0.510 rs10911242 chr1:183072147 C/T ch.1.3577855R chr1:183094577 LAMC1 0.64 11.08 0.51 1.35e-24 Fuchs's corneal dystrophy; LIHC cis rs77637988 0.578 rs12328506 chr2:48623184 C/T cg00032884 chr2:48540671 FOXN2 0.37 5.77 0.3 1.77e-8 Joint mobility (Beighton score); LIHC cis rs912057 0.671 rs1024246 chr6:6743505 A/T cg06612196 chr6:6737390 NA 0.51 9.78 0.47 4.46e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs11971779 0.680 rs6467840 chr7:139065401 A/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs9916302 0.904 rs34363096 chr17:37594294 G/A cg03013999 chr17:37608204 MED1 0.35 5.8 0.3 1.49e-8 Glomerular filtration rate (creatinine); LIHC cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC cis rs4689592 0.503 rs11945642 chr4:7051065 G/C cg02503808 chr4:7069936 GRPEL1 -0.73 -10.36 -0.49 4.54e-22 Monocyte percentage of white cells; LIHC cis rs11792861 0.926 rs75128146 chr9:111833791 G/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.79 -0.34 5e-11 Menarche (age at onset); LIHC cis rs1664789 1.000 rs1664786 chr5:53281711 C/T ch.5.1024479R chr5:53302184 ARL15 0.53 8.68 0.42 1.61e-16 Waist circumference adjusted for body mass index; LIHC cis rs826838 1.000 rs12366971 chr12:38737687 T/G cg13010199 chr12:38710504 ALG10B 0.65 7.92 0.39 3.46e-14 Heart rate; LIHC cis rs6088590 1.000 rs11696546 chr20:33452999 C/G cg06115741 chr20:33292138 TP53INP2 0.56 7.64 0.38 2.23e-13 Coronary artery disease; LIHC cis rs1801251 1.000 rs283471 chr2:233656627 G/A cg25237894 chr2:233734115 C2orf82 0.58 11.28 0.52 2.63e-25 Coronary artery disease; LIHC cis rs2274273 1.000 rs8011834 chr14:55625977 A/C cg01864836 chr14:55583639 NA -0.37 -6.7 -0.34 8.37e-11 Protein biomarker; LIHC trans rs1814175 0.935 rs7479914 chr11:49661351 T/C cg03929089 chr4:120376271 NA -0.89 -17.53 -0.69 1.56e-49 Height; LIHC cis rs9818758 0.607 rs34784192 chr3:49274823 G/T cg07636037 chr3:49044803 WDR6 -0.79 -8.19 -0.4 5.34e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs10256972 0.869 rs4720158 chr7:1040325 A/G cg16145915 chr7:1198662 ZFAND2A -0.29 -7.26 -0.37 2.65e-12 Longevity;Endometriosis; LIHC cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg05564831 chr3:52568323 NT5DC2 0.36 5.88 0.3 9.88e-9 Electroencephalogram traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20777956 chr18:60987812 BCL2 0.46 6.77 0.34 5.6e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02905964 chr19:29704262 UQCRFS1 0.5 6.81 0.35 4.42e-11 Lung function (FEV1/FVC); LIHC cis rs17401966 0.931 rs17410217 chr1:10371854 A/G cg15208524 chr1:10270712 KIF1B 0.42 6.35 0.32 6.93e-10 Hepatocellular carcinoma; LIHC cis rs2235573 0.527 rs139879 chr22:38364552 T/C cg03989125 chr22:38214979 NA -0.43 -5.99 -0.31 5.38e-9 Glioblastoma;Glioma; LIHC cis rs739401 0.572 rs739400 chr11:3016520 G/A cg08508325 chr11:3079039 CARS -0.31 -6.7 -0.34 8.83e-11 Longevity; LIHC cis rs2997447 0.846 rs3008226 chr1:26394997 A/C cg19633962 chr1:26362018 EXTL1 -0.58 -6.53 -0.33 2.37e-10 QRS complex (12-leadsum); LIHC cis rs7829975 0.511 rs2976902 chr8:8341105 T/G cg06636001 chr8:8085503 FLJ10661 0.61 8.84 0.43 5.27e-17 Mood instability; LIHC cis rs2070488 1.000 rs4147025 chr3:38456531 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.44 0.64 3.5e-41 Electrocardiographic conduction measures; LIHC cis rs2073300 0.609 rs6137939 chr20:23390206 C/T cg16736954 chr20:23401023 NAPB -0.7 -8.4 -0.41 1.25e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6032067 0.929 rs17424723 chr20:43814520 G/T cg11264863 chr20:43835661 SEMG1 -0.47 -5.8 -0.3 1.51e-8 Blood protein levels; LIHC cis rs6840360 1.000 rs6823194 chr4:152604543 T/C cg22705602 chr4:152727874 NA -0.3 -6.15 -0.32 2.17e-9 Intelligence (multi-trait analysis); LIHC cis rs919433 1.000 rs1346649 chr2:198166117 C/A cg03934865 chr2:198174659 NA -0.62 -10.19 -0.48 1.88e-21 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs782590 0.774 rs782630 chr2:55899425 T/C cg03859395 chr2:55845619 SMEK2 0.78 13.22 0.58 1.57e-32 Metabolic syndrome; LIHC cis rs9788682 1.000 rs7181447 chr15:78814567 A/G cg06917634 chr15:78832804 PSMA4 -0.5 -7.22 -0.36 3.4e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs1005277 0.579 rs1740732 chr10:38491385 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.42 -6.06 -0.31 3.65e-9 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg02290350 chr8:58132656 NA 0.5 9.72 0.47 7.22e-20 Developmental language disorder (linguistic errors); LIHC cis rs9911578 1.000 rs6503887 chr17:56993320 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs921968 0.508 rs72965103 chr2:219312469 T/C cg02176678 chr2:219576539 TTLL4 -0.57 -8.03 -0.4 1.59e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs2439831 0.850 rs28524541 chr15:44124831 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.44 0.42 9.04e-16 Lung cancer in ever smokers; LIHC cis rs11122272 0.668 rs2749712 chr1:231537751 T/A cg06096015 chr1:231504339 EGLN1 0.49 9.09 0.44 8.42e-18 Hemoglobin concentration; LIHC cis rs10791097 0.694 rs11222370 chr11:130744767 T/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7945718 0.621 rs6485992 chr11:12697359 C/T cg25843174 chr11:12811716 TEAD1 0.35 8.06 0.4 1.31e-14 Educational attainment (years of education); LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.6 -11.84 -0.54 2.5e-27 Prudent dietary pattern; LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg00800038 chr16:89945340 TCF25 -0.6 -9.74 -0.47 5.95e-20 Skin colour saturation; LIHC cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg17554472 chr22:41940697 POLR3H 0.57 6.4 0.33 5.26e-10 Vitiligo; LIHC cis rs708547 0.581 rs781661 chr4:57780307 A/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.49 -7.04 -0.36 1.05e-11 Response to bleomycin (chromatid breaks); LIHC cis rs1348850 0.626 rs1901825 chr2:178225331 A/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.82 12.96 0.57 1.6e-31 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9611565 0.694 rs4822032 chr22:41925535 T/C cg03806693 chr22:41940476 POLR3H -0.52 -6.95 -0.35 1.85e-11 Vitiligo; LIHC cis rs2180341 0.924 rs9285459 chr6:127631113 T/C cg27446573 chr6:127587934 RNF146 1.03 16.06 0.66 1.17e-43 Breast cancer; LIHC cis rs6733011 0.508 rs6542843 chr2:99533729 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.31 -0.32 8.82e-10 Bipolar disorder; LIHC cis rs9388451 0.839 rs10457469 chr6:126083658 G/A cg06289844 chr6:126071538 HEY2 0.39 6.79 0.34 5.05e-11 Brugada syndrome; LIHC cis rs2075371 0.933 rs1421481 chr7:133964380 A/C cg11752832 chr7:134001865 SLC35B4 0.51 8.02 0.4 1.66e-14 Mean platelet volume; LIHC cis rs10078 0.898 rs2241598 chr5:438564 C/T cg07599136 chr5:415885 AHRR -0.55 -8.68 -0.42 1.61e-16 Fat distribution (HIV); LIHC trans rs11039798 0.588 rs10437592 chr11:48598859 G/T cg15704280 chr7:45808275 SEPT13 0.58 6.47 0.33 3.44e-10 Axial length; LIHC cis rs709400 0.628 rs4906321 chr14:103878882 C/T cg26031613 chr14:104095156 KLC1 0.52 6.47 0.33 3.34e-10 Body mass index; LIHC cis rs1823913 1.000 rs4853568 chr2:192126190 G/A cg12404831 chr2:192114017 MYO1B -0.34 -6.72 -0.34 7.51e-11 Obesity-related traits; LIHC cis rs1823913 1.000 rs4853561 chr2:192107706 T/C cg12404831 chr2:192114017 MYO1B -0.34 -6.83 -0.35 3.85e-11 Obesity-related traits; LIHC cis rs9393692 0.875 rs9358917 chr6:26284417 T/C cg05868516 chr6:26286170 HIST1H4H 0.41 6.31 0.32 8.62e-10 Educational attainment; LIHC cis rs12477438 1.000 rs11897712 chr2:99735697 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.06 -10.89 -0.51 6.62e-24 Chronic sinus infection; LIHC trans rs7613875 0.641 rs6793528 chr3:50100188 C/A cg21659725 chr3:3221576 CRBN -0.55 -8.16 -0.4 6.51e-15 Body mass index; LIHC cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg03060546 chr3:49711283 APEH -0.4 -6.18 -0.32 1.78e-9 Menarche (age at onset); LIHC cis rs8141529 0.732 rs5762788 chr22:29174770 G/T cg15103426 chr22:29168792 CCDC117 0.61 10.14 0.48 2.74e-21 Lymphocyte counts; LIHC cis rs1005277 0.579 rs2474587 chr10:38420666 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.89 -0.3 9.44e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8072100 0.817 rs9912101 chr17:45547078 A/G cg08085267 chr17:45401833 C17orf57 -0.43 -6.35 -0.32 6.89e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6502050 0.835 rs10163482 chr17:80110394 C/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs35306767 0.903 rs12264711 chr10:929525 T/C cg26597838 chr10:835615 NA 1.14 13.45 0.59 2.16e-33 Eosinophil percentage of granulocytes; LIHC cis rs5769765 0.955 rs8135816 chr22:50291976 G/C cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.23e-16 Schizophrenia; LIHC cis rs769267 0.896 rs2315610 chr19:19597240 T/C cg03709012 chr19:19516395 GATAD2A 1.02 18.33 0.7 8.9e-53 Tonsillectomy; LIHC cis rs9467773 0.967 rs9358954 chr6:26531178 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.18 0.44 4.13e-18 Bipolar disorder; LIHC cis rs2404602 1.000 rs12441433 chr15:76816015 G/A cg03037974 chr15:76606532 NA 0.7 13.64 0.59 4.13e-34 Blood metabolite levels; LIHC cis rs11190604 1.000 rs2495743 chr10:102329739 G/C cg07080220 chr10:102295463 HIF1AN 0.54 7.49 0.38 6.12e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs12497850 0.931 rs7430501 chr3:48890119 C/T cg07636037 chr3:49044803 WDR6 0.93 16.94 0.68 3.74e-47 Parkinson's disease; LIHC cis rs4820539 0.902 rs9612237 chr22:23472954 T/C cg21100191 chr22:23484243 RTDR1 0.91 16.74 0.67 2.23e-46 Bone mineral density; LIHC cis rs60871478 0.636 rs4276575 chr7:900035 C/T cg05535760 chr7:792225 HEATR2 -0.76 -6.31 -0.32 8.76e-10 Cerebrospinal P-tau181p levels; LIHC cis rs10504073 0.527 rs118032023 chr8:49926296 A/T cg00325661 chr8:49890786 NA 0.39 9.57 0.46 2.29e-19 Blood metabolite ratios; LIHC cis rs17711722 0.583 rs11768292 chr7:65474801 G/T cg26939375 chr7:64535504 NA -0.44 -6.04 -0.31 4e-9 Calcium levels; LIHC cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg05552183 chr6:42928497 GNMT 0.81 12.18 0.55 1.31e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7224685 0.569 rs28481302 chr17:4011527 T/G cg09695851 chr17:3907499 NA 0.61 6.94 0.35 2.02e-11 Type 2 diabetes; LIHC cis rs6582630 0.519 rs2387812 chr12:38381480 A/G cg26384229 chr12:38710491 ALG10B 0.57 8.0 0.4 2e-14 Drug-induced liver injury (flucloxacillin); LIHC trans rs877282 0.583 rs12358255 chr10:828626 C/T cg22713356 chr15:30763199 NA 0.75 6.38 0.33 5.71e-10 Uric acid levels; LIHC cis rs17152411 0.625 rs10751611 chr10:126658893 A/G cg07906193 chr10:126599966 NA -0.3 -5.94 -0.31 7.03e-9 Height; LIHC cis rs2549003 1.000 rs2549009 chr5:131826765 T/C cg02551604 chr5:131831745 NA 0.49 7.27 0.37 2.4e-12 Asthma (sex interaction); LIHC cis rs317689 0.690 rs10878946 chr12:69642315 C/T cg20891283 chr12:69753455 YEATS4 0.48 6.78 0.34 5.35e-11 Response to diuretic therapy; LIHC cis rs611744 0.935 rs679077 chr8:109244742 G/T cg21045802 chr8:109455806 TTC35 0.5 8.65 0.42 1.99e-16 Dupuytren's disease; LIHC cis rs11758351 1.000 rs80259160 chr6:26190199 C/T cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs757110 0.933 rs7124355 chr11:17412960 C/T cg15432903 chr11:17409602 KCNJ11 -0.51 -7.47 -0.37 6.56e-13 Type 2 diabetes; LIHC cis rs1580019 0.587 rs9638880 chr7:32552401 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.85 0.43 4.64e-17 Cognitive ability; LIHC cis rs735396 1.000 rs2259852 chr12:121434833 G/A cg25281562 chr12:121454272 C12orf43 0.34 5.92 0.3 7.73e-9 N-glycan levels; LIHC cis rs9649213 0.593 rs13246725 chr7:97914898 C/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.06e-19 Renal cell carcinoma; LIHC cis rs8108269 0.868 rs10421566 chr19:46159123 C/T cg13320842 chr19:46175254 GIPR 0.41 7.7 0.38 1.5e-13 Type 2 diabetes; LIHC cis rs7412746 0.658 rs6677420 chr1:150946490 G/A cg17724175 chr1:150552817 MCL1 0.41 7.93 0.39 3.18e-14 Melanoma; LIHC cis rs7534824 0.583 rs6577225 chr1:101506126 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 6.97 0.35 1.61e-11 Refractive astigmatism; LIHC cis rs9640161 0.830 rs3757424 chr7:150067679 C/A cg21361702 chr7:150065534 REPIN1 0.51 7.28 0.37 2.33e-12 Blood protein levels;Circulating chemerin levels; LIHC cis rs8005677 0.828 rs712486 chr14:23425041 A/G cg25600027 chr14:23388339 RBM23 -0.4 -5.78 -0.3 1.72e-8 Cognitive ability (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13410609 chr19:50291885 AP2A1 0.43 6.48 0.33 3.23e-10 Longevity; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg27432699 chr2:27873401 GPN1 0.5 7.2 0.36 3.95e-12 Total body bone mineral density; LIHC cis rs10883723 0.737 rs7074444 chr10:104249922 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.76 0.57 9.25e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs8072100 0.817 rs6505049 chr17:45675781 G/A cg08085267 chr17:45401833 C17orf57 0.39 5.82 0.3 1.36e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg00280220 chr17:61926910 NA 0.4 6.25 0.32 1.23e-9 Prudent dietary pattern; LIHC cis rs875971 0.862 rs801195 chr7:66026115 A/G cg18252515 chr7:66147081 NA 0.45 6.61 0.34 1.5e-10 Aortic root size; LIHC cis rs921968 0.541 rs664514 chr2:219329819 A/G cg18887096 chr2:219472410 PLCD4 0.37 5.78 0.3 1.64e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2463822 0.844 rs7104149 chr11:62171627 A/G cg06239285 chr11:62104954 ASRGL1 -0.84 -5.83 -0.3 1.29e-8 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs1185460 1.000 rs7938944 chr11:118954066 T/C cg23280166 chr11:118938394 VPS11 0.53 7.0 0.35 1.35e-11 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14832358 chr2:45837811 SRBD1 0.5 7.49 0.38 6.07e-13 Pancreatic cancer; LIHC cis rs7618501 0.521 rs952594 chr3:49908023 G/A cg24110177 chr3:50126178 RBM5 -0.54 -8.33 -0.41 2.04e-15 Intelligence (multi-trait analysis); LIHC cis rs2549003 0.933 rs7719499 chr5:131814091 C/G cg02551604 chr5:131831745 NA -0.46 -6.69 -0.34 9.19e-11 Asthma (sex interaction); LIHC cis rs4819052 0.851 rs914218 chr21:46698445 G/C cg22633049 chr21:46681294 NA -0.38 -6.32 -0.32 8.16e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6876835 0.511 rs58514300 chr5:6598022 C/T cg04204831 chr5:6583394 LOC255167 0.42 6.44 0.33 4.04e-10 Visceral fat; LIHC cis rs4819052 0.851 rs2838856 chr21:46680766 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.85 0.39 5.37e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg17179660 chr6:151773299 C6orf211;RMND1 -0.43 -6.54 -0.33 2.29e-10 Menarche (age at onset); LIHC cis rs9911578 0.740 rs368243 chr17:56708979 T/C cg12560992 chr17:57184187 TRIM37 0.63 8.12 0.4 8.25e-15 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10150615 chr22:24372951 LOC391322 0.46 6.81 0.35 4.41e-11 Cognitive function; LIHC cis rs55665837 0.778 rs11023212 chr11:14431709 G/A cg19336497 chr11:14380999 RRAS2 -0.49 -8.81 -0.43 6.6e-17 Vitamin D levels; LIHC cis rs765787 0.530 rs11854689 chr15:45516052 A/G cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC cis rs651907 0.535 rs11714444 chr3:101513682 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs17401966 0.838 rs12125535 chr1:10350849 T/A cg19773385 chr1:10388646 KIF1B -0.41 -7.44 -0.37 8.34e-13 Hepatocellular carcinoma; LIHC cis rs10847980 0.590 rs1979236 chr12:123325993 G/A cg18912006 chr12:123335444 HIP1R 0.72 7.44 0.37 8.06e-13 Adiponectin levels; LIHC cis rs1371867 0.846 rs1788189 chr8:101249762 G/T cg06002616 chr8:101225028 SPAG1 0.34 5.76 0.3 1.87e-8 Atrioventricular conduction; LIHC cis rs708547 0.830 rs1713994 chr4:57868367 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.63 8.95 0.44 2.24e-17 Response to bleomycin (chromatid breaks); LIHC cis rs733592 0.507 rs7138917 chr12:48455255 G/A cg21466736 chr12:48725269 NA 0.36 6.32 0.32 8.02e-10 Plateletcrit; LIHC cis rs6089829 0.962 rs2314130 chr20:61665129 G/T cg03213289 chr20:61660250 NA 0.5 8.91 0.43 2.99e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs1580019 0.883 rs6945294 chr7:32472099 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.49 6.62 0.34 1.36e-10 Cognitive ability; LIHC cis rs12497850 0.931 rs6442130 chr3:48778027 A/G cg07636037 chr3:49044803 WDR6 0.87 14.13 0.61 4.81e-36 Parkinson's disease; LIHC trans rs78049276 0.562 rs55965782 chr4:148378442 T/C cg13149281 chr14:23389818 RBM23;PRMT5 -0.65 -8.27 -0.41 2.96e-15 Pulse pressure; LIHC cis rs10416265 0.503 rs1981818 chr19:33615122 C/T cg27124370 chr19:33622961 WDR88 -0.59 -8.9 -0.43 3.26e-17 Bone properties (heel); LIHC trans rs800082 0.690 rs800081 chr3:144339980 C/T cg24215973 chr2:240111563 HDAC4 0.53 8.15 0.4 6.97e-15 Smoking behavior; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27402845 chr11:1000533 AP2A2 0.42 6.1 0.31 2.86e-9 Longevity; LIHC cis rs36051895 0.623 rs28872016 chr9:5253558 T/G cg02405213 chr9:5042618 JAK2 -0.62 -10.06 -0.48 4.95e-21 Pediatric autoimmune diseases; LIHC cis rs7659604 0.540 rs67150579 chr4:122704331 T/A cg19671926 chr4:122722719 EXOSC9 0.56 8.63 0.42 2.3e-16 Type 2 diabetes; LIHC cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg16262614 chr3:133464971 TF 0.29 6.38 0.33 5.9e-10 Iron status biomarkers; LIHC cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg06238570 chr21:40685208 BRWD1 -0.53 -8.69 -0.43 1.56e-16 Cognitive function; LIHC cis rs4908768 0.579 rs12137865 chr1:8868406 A/G cg20416874 chr1:8611966 RERE 0.44 6.66 0.34 1.12e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7172677 1.000 rs72730601 chr15:75421720 A/T cg09165964 chr15:75287851 SCAMP5 0.42 5.89 0.3 9.23e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs561341 0.783 rs512698 chr17:30292507 G/T cg20587970 chr11:113659929 NA -1.38 -11.72 -0.54 6.87e-27 Hip circumference adjusted for BMI; LIHC cis rs1800973 0.536 rs11177576 chr12:69671660 A/G cg20891283 chr12:69753455 YEATS4 -0.52 -5.96 -0.31 6.44e-9 Monocyte percentage of white cells;Monocyte count;Blood protein levels;Granulocyte percentage of myeloid white cells; LIHC cis rs6089829 0.962 rs6062393 chr20:61663230 G/A cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs67311347 1.000 rs6599094 chr3:40399593 A/G cg00656387 chr3:40428638 ENTPD3 0.39 6.42 0.33 4.57e-10 Renal cell carcinoma; LIHC cis rs10791097 0.694 rs4459316 chr11:130756176 T/C cg14779329 chr11:130786720 SNX19 0.42 6.34 0.32 7.1e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs921968 0.540 rs646295 chr2:219408558 A/C cg18887096 chr2:219472410 PLCD4 0.36 6.39 0.33 5.41e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC trans rs2363709 1.000 rs6770280 chr3:67416712 T/C cg13681781 chr9:139102396 QSOX2 0.81 6.33 0.32 7.66e-10 IgE levels; LIHC cis rs921968 0.565 rs13408305 chr2:219628183 G/A cg02985541 chr2:219472218 PLCD4 -0.38 -6.57 -0.33 1.83e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg07424592 chr7:64974309 NA 0.81 9.45 0.45 5.58e-19 Diabetic kidney disease; LIHC cis rs6951245 0.882 rs56048221 chr7:1092533 A/G cg08132940 chr7:1081526 C7orf50 -0.76 -6.94 -0.35 1.96e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618501 0.521 rs55692411 chr3:49911155 G/A cg24110177 chr3:50126178 RBM5 -0.54 -8.32 -0.41 2.12e-15 Intelligence (multi-trait analysis); LIHC cis rs11229555 0.645 rs11229430 chr11:58181104 G/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs8073060 0.544 rs225283 chr17:33934912 A/G cg19694781 chr19:47549865 TMEM160 -1.22 -12.6 -0.56 3.74e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6952808 0.771 rs10265944 chr7:1918337 C/T cg04267008 chr7:1944627 MAD1L1 -0.59 -8.96 -0.44 2.21e-17 Bipolar disorder and schizophrenia; LIHC cis rs10905065 1.000 rs7913067 chr10:5787305 C/T cg11519256 chr10:5708881 ASB13 0.45 5.99 0.31 5.46e-9 Menopause (age at onset); LIHC cis rs1198430 0.683 rs1077514 chr1:23766233 A/G cg13183780 chr1:23809682 ASAP3 0.37 6.4 0.33 5.27e-10 Total cholesterol levels; LIHC cis rs2304069 0.954 rs6579767 chr5:149406271 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.98 12.6 0.56 3.76e-30 HIV-1 control; LIHC trans rs7714584 1.000 rs6579804 chr5:150255931 T/C cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs713477 0.692 rs10146713 chr14:55911597 T/C cg13175173 chr14:55914753 NA -0.3 -6.64 -0.34 1.24e-10 Pediatric bone mineral content (femoral neck); LIHC cis rs8062405 1.000 rs62036624 chr16:28839930 G/T cg07451762 chr16:28383216 NA 0.32 6.12 0.31 2.56e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.85e-9 Total body bone mineral density; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg27037990 chr4:184427250 ING2 0.43 6.09 0.31 3.05e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs6600671 0.967 rs4844613 chr1:121173773 T/C cg09829573 chr1:144692074 NBPF9 -0.47 -8.57 -0.42 3.54e-16 Hip geometry; LIHC cis rs16828019 0.852 rs12044539 chr1:41661732 A/C cg20697417 chr1:41786797 NA 0.34 6.51 0.33 2.67e-10 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg06466757 chr4:1255808 NA 0.34 5.8 0.3 1.53e-8 Obesity-related traits; LIHC cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg10360323 chr17:41437877 NA 0.4 5.95 0.31 6.7e-9 Menopause (age at onset); LIHC cis rs11098499 0.738 rs10026493 chr4:120384194 C/G cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs17685 0.712 rs11770149 chr7:75791644 G/A cg01364799 chr7:75623366 TMEM120A -0.42 -6.25 -0.32 1.26e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.98 0.31 5.76e-9 Menopause (age at onset); LIHC cis rs3857067 0.806 rs10212784 chr4:95101638 C/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.58 -0.38 3.25e-13 QT interval; LIHC cis rs780094 0.564 rs4665978 chr2:27648726 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.81 -0.35 4.49e-11 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs1577917 0.958 rs34795473 chr6:86461799 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.98 -0.31 5.56e-9 Response to antipsychotic treatment; LIHC cis rs9326778 0.520 rs10042130 chr5:108818528 C/A cg17395555 chr5:108820864 NA -0.35 -5.98 -0.31 5.56e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.684 rs1827015 chr11:49585241 A/G cg03929089 chr4:120376271 NA -0.82 -14.9 -0.63 4.89e-39 Height; LIHC cis rs1843834 0.574 rs6436499 chr2:225456551 A/T cg12698349 chr2:225449008 CUL3 0.66 10.05 0.48 5.27e-21 IgE levels in asthmatics (D.p. specific); LIHC cis rs950169 0.541 rs10795 chr15:85177297 G/A cg03959625 chr15:84868606 LOC388152 0.44 6.11 0.31 2.64e-9 Schizophrenia; LIHC cis rs67311347 1.000 rs4973898 chr3:40459532 A/G cg09455208 chr3:40491958 NA -0.33 -6.64 -0.34 1.21e-10 Renal cell carcinoma; LIHC cis rs5769765 0.817 rs8142561 chr22:50291750 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.16 -0.44 4.85e-18 Schizophrenia; LIHC cis rs68170813 0.559 rs1018947 chr7:106851939 A/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs1580019 0.844 rs1584615 chr7:32503258 G/C cg06627557 chr7:32535165 LSM5;AVL9 0.98 16.75 0.67 2.13e-46 Cognitive ability; LIHC cis rs250677 0.652 rs1422582 chr5:148436925 T/C cg18129178 chr5:148520854 ABLIM3 -0.55 -7.1 -0.36 7.14e-12 Breast cancer; LIHC cis rs2404602 0.692 rs58973160 chr15:77000342 T/C cg03037974 chr15:76606532 NA 0.73 14.39 0.61 5.01e-37 Blood metabolite levels; LIHC cis rs2012796 0.665 rs72703728 chr14:81834523 G/A cg23690444 chr14:81902736 NA -0.45 -6.21 -0.32 1.52e-9 Night sleep phenotypes; LIHC trans rs2727020 0.612 rs603672 chr11:49234566 T/A cg03929089 chr4:120376271 NA 0.78 13.8 0.6 9.9e-35 Coronary artery disease; LIHC cis rs6430585 0.528 rs721765 chr2:136748779 C/A cg25344623 chr2:136566232 LCT -0.37 -5.96 -0.31 6.45e-9 Corneal structure; LIHC cis rs17376456 0.825 rs13164315 chr5:93147421 A/G cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs2559856 1.000 rs2695284 chr12:102089318 A/G cg12924262 chr12:102091054 CHPT1 -0.53 -8.58 -0.42 3.33e-16 Blood protein levels; LIHC cis rs7707921 0.522 rs10070637 chr5:81490608 A/G cg15871215 chr5:81402204 ATG10 0.61 8.27 0.41 2.92e-15 Breast cancer; LIHC cis rs4253772 0.550 rs9615913 chr22:46668515 A/T cg09491104 chr22:46646882 C22orf40 0.64 7.39 0.37 1.11e-12 LDL cholesterol;Cholesterol, total; LIHC cis rs9916302 0.904 rs8077104 chr17:37530510 A/G cg00129232 chr17:37814104 STARD3 0.4 6.34 0.32 7.45e-10 Glomerular filtration rate (creatinine); LIHC cis rs751728 0.544 rs2281820 chr6:33768897 A/G cg25922239 chr6:33757077 LEMD2 0.43 6.25 0.32 1.2e-9 Crohn's disease; LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg00091569 chr3:40428383 ENTPD3 -0.4 -6.79 -0.34 4.83e-11 Renal cell carcinoma; LIHC cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg13770153 chr20:60521292 NA -0.33 -6.4 -0.33 4.98e-10 Body mass index; LIHC trans rs7644516 0.646 rs2052761 chr3:25924669 A/G cg06495728 chr3:187462459 BCL6 -0.49 -6.47 -0.33 3.41e-10 DNA methylation (variation); LIHC cis rs11792861 0.926 rs77567374 chr9:111835034 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 8.86 0.43 4.34e-17 Menarche (age at onset); LIHC cis rs12188164 0.543 rs2434694 chr5:462734 C/T cg16584290 chr5:462447 EXOC3 0.37 6.03 0.31 4.14e-9 Cystic fibrosis severity; LIHC cis rs713477 1.000 rs7142204 chr14:55908436 G/T cg13175173 chr14:55914753 NA 0.35 8.15 0.4 7.17e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs919433 0.854 rs13013049 chr2:198208664 C/T cg03934865 chr2:198174659 NA -0.57 -8.88 -0.43 3.92e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs861318 0.702 rs7532207 chr1:159024424 A/T cg11003133 chr1:159046391 AIM2 -0.33 -6.38 -0.33 5.77e-10 Obesity-related traits; LIHC cis rs918629 0.761 rs7705720 chr5:95280033 T/C cg10483112 chr5:95245456 ELL2 -0.36 -6.1 -0.31 2.85e-9 IgG glycosylation; LIHC cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.09 -0.44 8.29e-18 Bipolar disorder; LIHC cis rs1005277 0.579 rs1780133 chr10:38499509 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC trans rs11098499 0.754 rs878372 chr4:120238780 A/C cg25214090 chr10:38739885 LOC399744 0.53 8.54 0.42 4.59e-16 Corneal astigmatism; LIHC cis rs11764590 0.694 rs6972969 chr7:2099331 A/G cg23422044 chr7:1970798 MAD1L1 -0.55 -8.76 -0.43 9.2e-17 Neuroticism; LIHC cis rs10751667 0.666 rs6597960 chr11:977036 C/T cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs826838 1.000 rs7299124 chr12:39002661 T/C cg26384229 chr12:38710491 ALG10B 0.92 12.12 0.55 2.31e-28 Heart rate; LIHC cis rs477895 0.639 rs35858916 chr11:63950529 T/G cg04317338 chr11:64019027 PLCB3 0.85 10.22 0.48 1.41e-21 Mean platelet volume; LIHC cis rs17818399 1.000 rs17818399 chr2:46826026 A/C cg02822958 chr2:46747628 ATP6V1E2 0.49 7.61 0.38 2.64e-13 Height; LIHC cis rs11822910 0.911 rs11828218 chr11:57196223 C/G cg00522883 chr11:57194120 SLC43A3 0.65 8.97 0.44 1.98e-17 Platelet distribution width; LIHC cis rs12971120 0.891 rs2278158 chr18:72178300 G/T cg26446133 chr18:72167187 CNDP2 -0.79 -14.23 -0.61 2e-36 Refractive error; LIHC cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg17971929 chr21:40555470 PSMG1 0.85 10.53 0.49 1.17e-22 Cognitive function; LIHC cis rs372883 0.580 rs2254038 chr21:30745722 C/T cg24692254 chr21:30365293 RNF160 0.48 5.97 0.31 5.82e-9 Pancreatic cancer; LIHC cis rs7100689 0.622 rs10749569 chr10:82129892 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs10838687 0.736 rs326224 chr11:47255598 T/C cg25783544 chr11:47291846 MADD -0.47 -5.86 -0.3 1.11e-8 Proinsulin levels; LIHC cis rs12048904 0.505 rs11166508 chr1:101233511 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.59 -9.14 -0.44 5.47e-18 Multiple sclerosis; LIHC cis rs2153535 0.580 rs9505448 chr6:8459804 A/G cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs6429082 0.818 rs210037 chr1:235649501 A/G cg26050004 chr1:235667680 B3GALNT2 0.5 7.6 0.38 2.84e-13 Adiposity; LIHC cis rs2070488 0.965 rs35553573 chr3:38441439 C/T cg24069376 chr3:38537580 EXOG 0.41 7.53 0.38 4.48e-13 Electrocardiographic conduction measures; LIHC cis rs6089829 0.888 rs4809468 chr20:61673566 T/C cg03213289 chr20:61660250 NA 0.52 9.08 0.44 9.01e-18 Prostate cancer (SNP x SNP interaction); LIHC cis rs600806 0.778 rs4970731 chr1:109995459 T/C cg11161837 chr1:110010384 SYPL2 0.44 5.8 0.3 1.55e-8 Intelligence (multi-trait analysis); LIHC cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg09222892 chr1:25734099 RHCE -0.48 -8.71 -0.43 1.31e-16 Erythrocyte sedimentation rate; LIHC cis rs9303401 0.659 rs12944971 chr17:56988801 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.99 13.76 0.6 1.35e-34 Cognitive test performance; LIHC cis rs10792665 0.934 rs10898063 chr11:82672020 A/G cg24227371 chr11:82718527 RAB30 -0.3 -6.93 -0.35 2.07e-11 Obesity-related traits; LIHC cis rs7953249 0.564 rs1183910 chr12:121420807 G/A cg02403541 chr12:121454288 C12orf43 0.43 7.09 0.36 7.5e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs2204008 0.840 rs11181795 chr12:38401129 A/G cg26384229 chr12:38710491 ALG10B 0.6 8.27 0.41 3.1e-15 Bladder cancer; LIHC trans rs941408 1.000 rs1640273 chr19:2803227 C/T cg19676328 chr12:49525230 TUBA1B -0.4 -6.55 -0.33 2.11e-10 Total cholesterol levels; LIHC cis rs7091068 0.671 rs591392 chr10:95406081 G/A cg20715218 chr10:95462985 C10orf4 -0.61 -7.0 -0.35 1.39e-11 Urinary tract infection frequency; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09250149 chr16:85684353 KIAA0182 -0.42 -6.45 -0.33 3.91e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg20887711 chr4:1340912 KIAA1530 0.78 12.22 0.55 9.56e-29 Longevity; LIHC cis rs2120019 1.000 rs34237279 chr15:75361121 A/G cg17294928 chr15:75287854 SCAMP5 -0.57 -8.73 -0.43 1.16e-16 Blood trace element (Zn levels); LIHC trans rs11039798 0.614 rs116427493 chr11:48776141 C/T cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg06634786 chr22:41940651 POLR3H 0.82 8.99 0.44 1.76e-17 Vitiligo; LIHC cis rs801193 0.904 rs4718405 chr7:66254646 A/G cg18876405 chr7:65276391 NA 0.41 6.91 0.35 2.32e-11 Aortic root size; LIHC cis rs7772486 0.790 rs9376970 chr6:146241472 A/C cg05347473 chr6:146136440 FBXO30 -0.39 -6.24 -0.32 1.27e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs738322 0.935 rs133014 chr22:38571087 T/G cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs6714710 0.603 rs13008968 chr2:98435982 C/T cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs4908768 0.596 rs4908516 chr1:8879610 G/C cg20416874 chr1:8611966 RERE 0.46 6.23 0.32 1.34e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs2727020 0.538 rs61885230 chr11:49128958 T/C cg15704280 chr7:45808275 SEPT13 -0.58 -9.15 -0.44 5.24e-18 Coronary artery disease; LIHC cis rs2425143 1.000 rs56052651 chr20:34344084 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.55 -6.91 -0.35 2.35e-11 Blood protein levels; LIHC cis rs4665809 0.793 rs6546715 chr2:26261520 G/A cg27170947 chr2:26402098 FAM59B -0.65 -8.17 -0.4 6.17e-15 Gut microbiome composition (summer); LIHC cis rs7208859 0.623 rs9911490 chr17:29073013 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6461049 0.800 rs3778977 chr7:2159746 C/T cg14004847 chr7:1930337 MAD1L1 -0.42 -6.16 -0.32 1.99e-9 Schizophrenia; LIHC trans rs875971 0.558 rs4433015 chr7:65639723 A/C cg26939375 chr7:64535504 NA -0.46 -6.9 -0.35 2.6e-11 Aortic root size; LIHC cis rs4853525 0.522 rs7574840 chr2:191584236 C/G cg10560079 chr2:191398806 TMEM194B -0.42 -6.04 -0.31 4.1e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC trans rs10448080 0.879 rs240946 chr8:28568905 A/G cg15257755 chr8:22225668 SLC39A14 -0.38 -6.12 -0.31 2.62e-9 Height; LIHC cis rs7000551 0.751 rs1116084 chr8:22395309 C/T cg13512537 chr8:22265999 SLC39A14 -0.38 -6.7 -0.34 8.57e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs11190604 1.000 rs2495739 chr10:102335507 C/T cg07080220 chr10:102295463 HIF1AN 0.56 7.81 0.39 6.86e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9560113 0.959 rs9555802 chr13:112179504 T/C cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs6499244 0.530 rs4275849 chr16:69832105 G/A cg15192750 chr16:69999425 NA 0.35 5.72 0.3 2.3e-8 Menarche (age at onset); LIHC cis rs6951245 0.832 rs79808627 chr7:1092519 C/G cg08132940 chr7:1081526 C7orf50 -0.75 -6.86 -0.35 3.27e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs941408 1.000 rs1736182 chr19:2798686 T/G cg19676328 chr12:49525230 TUBA1B -0.44 -6.42 -0.33 4.6e-10 Total cholesterol levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03621406 chr19:9930365 FBXL12 -0.5 -6.15 -0.32 2.17e-9 Systolic blood pressure; LIHC cis rs1577917 1.000 rs7747824 chr6:86647106 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.79 -0.39 7.93e-14 Response to antipsychotic treatment; LIHC cis rs796364 0.512 rs1653290 chr2:201078165 A/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.51 5.77 0.3 1.82e-8 Schizophrenia; LIHC trans rs208520 0.690 rs12213581 chr6:66735818 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 9.02 0.44 1.34e-17 Exhaled nitric oxide output; LIHC cis rs4654899 0.929 rs7515845 chr1:21314455 G/A cg08539965 chr1:21396338 EIF4G3 0.34 5.93 0.31 7.44e-9 Superior frontal gyrus grey matter volume; LIHC cis rs2421770 0.530 rs6484784 chr11:35368347 A/C cg13971030 chr11:35366721 SLC1A2 0.44 7.5 0.38 5.59e-13 Staphylococcus aureus nasal carriage (persistent); LIHC trans rs916888 0.687 rs199456 chr17:44797919 C/T cg13957321 chr17:43675089 NA 0.5 7.97 0.4 2.46e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4934494 0.768 rs67111731 chr10:91419285 C/G cg19698084 chr10:91461284 KIF20B -0.5 -6.52 -0.33 2.47e-10 Red blood cell count; LIHC cis rs2404602 0.967 rs2083762 chr15:76907376 T/C cg03037974 chr15:76606532 NA 0.71 13.51 0.59 1.28e-33 Blood metabolite levels; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs7246657 0.943 rs2291004 chr19:37997952 C/A cg23950597 chr19:37808831 NA -0.49 -6.36 -0.33 6.42e-10 Coronary artery calcification; LIHC cis rs3824867 0.770 rs11820680 chr11:47452744 C/T cg20307385 chr11:47447363 PSMC3 -0.58 -7.96 -0.4 2.62e-14 Mean corpuscular hemoglobin; LIHC cis rs4759375 0.850 rs28503862 chr12:123867106 C/T cg00376283 chr12:123451042 ABCB9 0.5 6.35 0.32 6.89e-10 HDL cholesterol; LIHC cis rs6688363 0.943 rs1016732 chr1:160086968 A/G cg22802111 chr1:160068614 IGSF8 0.43 6.2 0.32 1.65e-9 Response to antipsychotic treatment; LIHC cis rs739401 0.611 rs401707 chr11:3050965 T/C cg25174290 chr11:3078921 CARS 0.61 9.13 0.44 6.05e-18 Longevity; LIHC cis rs7843479 0.601 rs727693 chr8:21850116 A/G cg17168535 chr8:21777572 XPO7 0.57 10.06 0.48 5.02e-21 Mean corpuscular volume; LIHC cis rs13191362 0.935 rs67337490 chr6:162953961 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.7 6.05 0.31 3.91e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23376870 chr14:90422459 TDP1;C14orf143 0.41 6.41 0.33 4.84e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.739 rs66539935 chr3:47025327 C/T cg02527881 chr3:46936655 PTH1R 0.33 6.34 0.32 7.38e-10 Colorectal cancer; LIHC trans rs4824093 0.610 rs2208023 chr22:50249983 A/G cg09872104 chr7:134855509 C7orf49 -0.77 -6.25 -0.32 1.26e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs1552244 0.515 rs111560858 chr3:10166845 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs7520050 0.966 rs785479 chr1:46492144 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.82 0.3 1.38e-8 Red blood cell count;Reticulocyte count; LIHC cis rs11711311 1.000 rs9809850 chr3:113429010 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -6.92 -0.35 2.18e-11 IgG glycosylation; LIHC trans rs10506458 0.834 rs12426860 chr12:63387948 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.59 -0.5 7.59e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs4689388 0.679 rs1046316 chr4:6304087 A/G cg00701064 chr4:6280414 WFS1 0.39 5.87 0.3 1.04e-8 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs9326248 0.581 rs10892076 chr11:116988936 G/A cg26566898 chr11:117069891 TAGLN 0.43 6.74 0.34 6.91e-11 Blood protein levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11646757 chr7:128095699 C7orf68 0.41 6.21 0.32 1.54e-9 Cognitive function; LIHC cis rs1799949 1.000 rs35070007 chr17:41316747 C/G cg25072359 chr17:41440525 NA -0.38 -6.18 -0.32 1.8e-9 Menopause (age at onset); LIHC cis rs2439831 1.000 rs28666488 chr15:43741090 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.65 0.42 2.04e-16 Lung cancer in ever smokers; LIHC cis rs9457247 0.561 rs916331 chr6:167470559 T/G cg12798992 chr6:167411361 FGFR1OP 0.47 6.97 0.35 1.63e-11 Crohn's disease; LIHC cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.34 0.55 3.52e-29 Alzheimer's disease; LIHC cis rs801193 1.000 rs2659912 chr7:66157999 G/C cg18876405 chr7:65276391 NA 0.43 7.36 0.37 1.34e-12 Aortic root size; LIHC cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg18306943 chr3:40428807 ENTPD3 0.34 6.09 0.31 2.96e-9 Renal cell carcinoma; LIHC cis rs4927850 1.000 rs4927850 chr3:195751630 C/T cg12923728 chr3:195709715 SDHAP1 0.7 10.06 0.48 4.84e-21 Pancreatic cancer; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg03874509 chr1:107600012 PRMT6 0.76 12.1 0.55 2.79e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6942756 0.531 rs9649531 chr7:128927659 T/C cg02491457 chr7:128862824 NA 0.49 7.48 0.37 6.49e-13 White matter hyperintensity burden; LIHC cis rs11673344 0.764 rs472226 chr19:37458713 A/C cg27390819 chr19:37464633 NA -0.52 -6.21 -0.32 1.52e-9 Obesity-related traits; LIHC cis rs3793683 0.928 rs2148666 chr10:134553785 A/G cg18305652 chr10:134549665 INPP5A 0.37 6.11 0.31 2.73e-9 Migraine; LIHC cis rs1816752 0.776 rs7998843 chr13:25017285 T/C cg02811702 chr13:24901961 NA 0.25 6.35 0.32 6.74e-10 Obesity-related traits; LIHC cis rs7095944 0.644 rs965484 chr10:126453481 T/C cg20435097 chr10:126320824 FAM53B 0.38 6.38 0.33 5.7e-10 Asthma; LIHC trans rs634534 0.622 rs552130 chr11:65732800 T/C cg17712092 chr4:129076599 LARP1B 0.7 11.62 0.53 1.51e-26 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs12644436 0.628 rs9991148 chr4:88781760 G/T cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs7945718 0.621 rs4606460 chr11:12687781 A/G cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs12477438 0.765 rs7340412 chr2:99661148 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs67478160 0.655 rs4900598 chr14:104281541 T/C cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.5 -0.38 5.56e-13 Schizophrenia; LIHC trans rs4942242 0.763 rs7326281 chr13:44233186 G/A cg19169023 chr15:41853346 TYRO3 -0.46 -6.73 -0.34 7.11e-11 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.87 0.78 6.99e-71 Height; LIHC cis rs858239 0.600 rs7785842 chr7:23141706 T/A cg23682824 chr7:23144976 KLHL7 0.45 6.79 0.34 5e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs3741404 0.584 rs645461 chr11:63893694 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.74 -11.63 -0.53 1.41e-26 Platelet count; LIHC cis rs818427 0.865 rs1093611 chr5:112218476 A/T cg07820702 chr5:112228657 REEP5 0.37 5.93 0.31 7.4e-9 Total body bone mineral density; LIHC cis rs8084351 0.569 rs876553 chr18:50776747 C/T cg24270629 chr18:50823537 DCC -0.46 -6.84 -0.35 3.68e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs244731 0.959 rs9313752 chr5:176645435 G/T cg16006841 chr5:176797999 RGS14 -0.6 -6.06 -0.31 3.56e-9 Urate levels in lean individuals; LIHC cis rs10751667 0.643 rs11246362 chr11:969818 C/T cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs11997175 0.603 rs7462153 chr8:33814607 C/T ch.8.33884649F chr8:33765107 NA 0.4 6.59 0.34 1.68e-10 Body mass index; LIHC cis rs11630290 0.566 rs4777395 chr15:64161693 T/G cg12036633 chr15:63758958 NA 0.63 6.82 0.35 4.14e-11 Iris characteristics; LIHC cis rs7843479 0.965 rs2291317 chr8:21827162 C/T cg17168535 chr8:21777572 XPO7 0.47 7.52 0.38 4.96e-13 Mean corpuscular volume; LIHC cis rs7412746 0.658 rs1546376 chr1:150937661 A/G cg18016565 chr1:150552671 MCL1 0.52 9.67 0.46 1.03e-19 Melanoma; LIHC cis rs80282103 0.867 rs11819178 chr10:1098417 A/G cg08668510 chr10:1095578 IDI1 0.71 7.06 0.36 9.46e-12 Glomerular filtration rate (creatinine); LIHC cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs644799 1.000 rs568668 chr11:95528209 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.52e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6430585 0.583 rs58509842 chr2:136586027 G/A cg15123519 chr2:136567270 LCT -0.38 -5.82 -0.3 1.38e-8 Corneal structure; LIHC cis rs2180341 0.782 rs6912196 chr6:127722732 C/G cg24812749 chr6:127587940 RNF146 0.8 12.32 0.55 4.16e-29 Breast cancer; LIHC cis rs4824093 0.610 rs4141437 chr22:50243719 C/G cg22709217 chr22:50311962 ALG12;CRELD2 0.73 5.97 0.31 6.08e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs644799 0.511 rs12791736 chr11:95475399 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.54 6.88 0.35 2.8e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4975709 0.610 rs6886669 chr5:1867830 T/C cg15595755 chr5:1867978 NA 0.42 8.61 0.42 2.66e-16 Cardiovascular disease risk factors; LIHC cis rs9733 0.596 rs6685702 chr1:150656307 A/G cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Tonsillectomy; LIHC cis rs1941023 0.606 rs7946122 chr11:60172770 G/A cg08716584 chr11:60157161 MS4A7 -0.36 -8.25 -0.41 3.45e-15 Congenital heart disease (maternal effect); LIHC cis rs1401454 1.000 rs2351958 chr11:16248020 C/A cg10927848 chr11:16298618 SOX6 -0.33 -6.26 -0.32 1.18e-9 Blood pressure; LIHC cis rs7131987 0.934 rs7316004 chr12:29411698 C/T cg21486233 chr12:29375141 FAR2 0.31 6.25 0.32 1.22e-9 QT interval; LIHC cis rs708547 0.599 rs2948348 chr4:57848772 G/A cg25525207 chr4:57843836 C4orf14;POLR2B -0.43 -6.81 -0.35 4.36e-11 Response to bleomycin (chromatid breaks); LIHC cis rs9916302 0.904 rs7216086 chr17:37709422 G/A cg00129232 chr17:37814104 STARD3 -0.41 -6.59 -0.34 1.64e-10 Glomerular filtration rate (creatinine); LIHC cis rs12926788 0.640 rs73551577 chr16:24845143 G/A cg00152838 chr16:24741724 TNRC6A -0.5 -6.17 -0.32 1.94e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs17818399 0.620 rs6739397 chr2:46858321 G/C cg02822958 chr2:46747628 ATP6V1E2 0.37 5.87 0.3 1.01e-8 Height; LIHC cis rs6424115 0.729 rs1737362 chr1:24054800 T/C cg10978503 chr1:24200527 CNR2 0.29 6.8 0.35 4.59e-11 Immature fraction of reticulocytes; LIHC cis rs6089584 0.819 rs1467593 chr20:60601432 T/G cg23262073 chr20:60523788 NA 0.3 6.01 0.31 4.74e-9 Body mass index; LIHC cis rs4660306 0.961 rs2152077 chr1:45986670 G/T cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.64 -0.34 1.2e-10 Homocysteine levels; LIHC trans rs7246657 0.882 rs6508716 chr19:37819010 T/C cg10208301 chr11:6592745 DNHD1 0.47 6.68 0.34 9.96e-11 Coronary artery calcification; LIHC cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs2463822 0.614 rs117699706 chr11:62161659 T/C cg06239285 chr11:62104954 ASRGL1 -0.92 -6.29 -0.32 9.75e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs807029 0.533 rs2863095 chr10:102746503 C/T cg17130504 chr10:102756923 LZTS2 0.56 7.77 0.39 9.27e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs8067354 0.681 rs76856339 chr17:57800966 G/A cg13753209 chr17:57696993 CLTC 0.78 12.34 0.56 3.34e-29 Hemoglobin concentration; LIHC cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg27297192 chr10:134578999 INPP5A 0.55 7.7 0.38 1.52e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2842992 0.513 rs7759086 chr6:160193853 A/G cg11366901 chr6:160182831 ACAT2 0.87 15.12 0.63 6.55e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs1023500 0.551 rs61665536 chr22:42512613 A/G cg15557168 chr22:42548783 NA 0.43 6.78 0.34 5.3e-11 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24262715 chr15:44038991 PDIA3;CATSPER2P1 0.44 6.14 0.32 2.26e-9 Lung function (FEV1/FVC); LIHC cis rs600806 0.850 rs3768493 chr1:109935505 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs9322817 0.902 rs9322812 chr6:105194651 A/G cg02098413 chr6:105308735 HACE1 -0.38 -6.13 -0.31 2.38e-9 Thyroid stimulating hormone; LIHC cis rs1707322 0.686 rs2230658 chr1:46078854 A/G cg24296786 chr1:45957014 TESK2 0.43 6.25 0.32 1.2e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.54 -0.33 2.22e-10 Total body bone mineral density; LIHC cis rs11800820 0.517 rs12022808 chr1:246659163 C/A cg16700716 chr1:246684329 NA 0.43 7.22 0.36 3.31e-12 Obesity-related traits; LIHC cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg23758822 chr17:41437982 NA 0.92 17.02 0.68 1.74e-47 Menopause (age at onset); LIHC cis rs11792861 0.962 rs3750452 chr9:111801353 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.54 0.42 4.58e-16 Menarche (age at onset); LIHC cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg06238570 chr21:40685208 BRWD1 0.59 6.92 0.35 2.23e-11 Cognitive function; LIHC cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg02290350 chr8:58132656 NA 0.49 9.15 0.44 5.44e-18 Developmental language disorder (linguistic errors); LIHC cis rs10949834 0.652 rs2269082 chr7:73519875 A/G cg07137043 chr7:73588983 EIF4H -0.61 -7.24 -0.36 2.99e-12 Verbal memory performance (residualized delayed recall change); LIHC cis rs4304924 0.500 rs12585725 chr13:79220899 C/A cg01819759 chr13:79234251 RNF219 0.49 6.36 0.33 6.37e-10 Large artery stroke; LIHC cis rs7100689 0.646 rs7903701 chr10:82129268 T/C cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg06420487 chr17:61919686 SMARCD2 0.46 6.22 0.32 1.48e-9 Height; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg14893161 chr1:205819251 PM20D1 0.69 9.95 0.47 1.17e-20 Menarche (age at onset); LIHC cis rs79387448 0.638 rs6759588 chr2:103040159 A/G cg09003973 chr2:102972529 NA 1.19 9.31 0.45 1.6e-18 Gut microbiota (bacterial taxa); LIHC cis rs77861329 1.000 rs9809977 chr3:52166147 T/C cg08692210 chr3:52188851 WDR51A 0.83 7.85 0.39 5.47e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs79149102 0.579 rs7179097 chr15:75279240 T/G cg16226627 chr15:75307476 SCAMP5 0.54 9.83 0.47 3.01e-20 Lung cancer; LIHC trans rs7618501 0.521 rs11709573 chr3:49956628 C/T cg21659725 chr3:3221576 CRBN 0.56 8.23 0.41 4.04e-15 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.960 rs1964130 chr6:127677391 C/G cg27446573 chr6:127587934 RNF146 0.96 13.62 0.59 4.63e-34 Breast cancer; LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg00612595 chr21:47717864 NA -0.37 -6.08 -0.31 3.21e-9 Testicular germ cell tumor; LIHC cis rs12824058 0.831 rs11609362 chr12:130810526 T/C cg24229701 chr12:130821962 PIWIL1 0.44 6.78 0.34 5.4e-11 Menopause (age at onset); LIHC cis rs11864453 0.647 rs10492814 chr16:72126514 G/A cg16558253 chr16:72132732 DHX38 -0.45 -7.26 -0.37 2.55e-12 Fibrinogen levels; LIHC cis rs797680 0.856 rs569414 chr1:93784901 G/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.04 -0.31 3.95e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC trans rs10761482 0.566 rs10159663 chr10:62208417 A/G cg10096035 chr12:96392698 NA -0.4 -6.34 -0.32 7.26e-10 Schizophrenia; LIHC cis rs2412459 0.803 rs7165105 chr15:40273788 A/G cg02712587 chr15:40268421 EIF2AK4 0.55 5.79 0.3 1.63e-8 Response to haloperidol in psychosis; LIHC cis rs7412746 0.552 rs4970980 chr1:150864992 A/C cg17724175 chr1:150552817 MCL1 0.38 7.5 0.38 5.42e-13 Melanoma; LIHC cis rs7716219 0.580 rs1396611 chr5:54878771 T/C cg14753740 chr5:54468940 CDC20B;MIR449C 0.43 5.9 0.3 8.93e-9 Height; LIHC cis rs68170813 0.559 rs7794598 chr7:106826381 C/T cg02696742 chr7:106810147 HBP1 -0.53 -6.1 -0.31 2.87e-9 Coronary artery disease; LIHC cis rs11758351 1.000 rs11755210 chr6:26202768 C/T cg03854865 chr6:26224070 HIST1H3E 0.62 6.86 0.35 3.24e-11 Gout;Renal underexcretion gout; LIHC cis rs79839061 0.610 rs2306252 chr4:892116 T/C cg04824913 chr4:887549 GAK 0.57 6.94 0.35 1.94e-11 Intelligence (multi-trait analysis); LIHC cis rs2067615 0.524 rs10861645 chr12:107071130 C/T cg15890332 chr12:107067104 RFX4 0.27 6.3 0.32 9.42e-10 Heart rate; LIHC cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.76e-9 Menopause (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05904041 chr7:4802774 FOXK1 0.45 6.54 0.33 2.27e-10 Longevity; LIHC cis rs6545883 0.929 rs2463100 chr2:61659199 C/G cg15711740 chr2:61764176 XPO1 -0.45 -6.13 -0.31 2.42e-9 Tuberculosis; LIHC cis rs7772486 0.875 rs2777483 chr6:146329235 A/G cg23711669 chr6:146136114 FBXO30 0.66 11.53 0.53 3.33e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.02 -0.44 1.42e-17 Bipolar disorder; LIHC cis rs10751667 0.666 rs7105477 chr11:964271 C/G ch.11.42038R chr11:967971 AP2A2 0.56 10.22 0.48 1.38e-21 Alzheimer's disease (late onset); LIHC cis rs10838687 0.673 rs2290148 chr11:47346145 G/A cg26139080 chr11:47293733 MADD -0.42 -5.82 -0.3 1.39e-8 Proinsulin levels; LIHC trans rs9914544 0.545 rs35911764 chr17:18782582 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.59 -0.34 1.62e-10 Educational attainment (years of education); LIHC cis rs7116495 0.609 rs2885661 chr11:71588331 C/G cg26138937 chr11:71823887 C11orf51 1.17 9.03 0.44 1.25e-17 Severe influenza A (H1N1) infection; LIHC cis rs68170813 0.559 rs77150993 chr7:106817100 G/T cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17158424 chr11:33095023 TCP11L1 -0.27 -6.16 -0.32 2.09e-9 Calcium levels; LIHC cis rs9611565 0.512 rs2050033 chr22:42159229 G/T cg06634786 chr22:41940651 POLR3H 0.73 7.39 0.37 1.15e-12 Vitiligo; LIHC cis rs2842992 0.715 rs2277073 chr6:160182749 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.58 0.42 3.3e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs4716602 0.596 rs4997808 chr7:156158734 C/G cg16983916 chr7:156159713 NA -0.33 -5.91 -0.3 8.43e-9 Anti-saccade response; LIHC cis rs35110281 0.776 rs9983763 chr21:44990578 A/G cg04455712 chr21:45112962 RRP1B -0.45 -7.54 -0.38 4.25e-13 Mean corpuscular volume; LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg03854865 chr6:26224070 HIST1H3E 0.63 7.23 0.36 3.28e-12 Gout;Renal underexcretion gout; LIHC cis rs7959452 0.536 rs4761237 chr12:69776461 C/G cg22834771 chr12:69754056 YEATS4 -0.52 -9.21 -0.45 3.28e-18 Blood protein levels; LIHC cis rs611744 0.905 rs421695 chr8:109117403 T/C cg21045802 chr8:109455806 TTC35 0.5 8.44 0.42 8.98e-16 Dupuytren's disease; LIHC cis rs10493773 0.775 rs2069208 chr1:86117583 T/C cg17807903 chr1:86174739 ZNHIT6 -0.58 -10.72 -0.5 2.53e-23 Urate levels in overweight individuals; LIHC cis rs875971 0.862 rs4718319 chr7:65652784 C/A cg11764359 chr7:65958608 NA -0.84 -14.15 -0.61 4.2500000000000003e-36 Aortic root size; LIHC cis rs8180040 0.620 rs749511 chr3:47035735 A/C cg16586182 chr3:47516702 SCAP 0.47 8.51 0.42 5.69e-16 Colorectal cancer; LIHC cis rs2404602 0.692 rs12437733 chr15:77155562 A/G cg03037974 chr15:76606532 NA 0.73 14.24 0.61 1.94e-36 Blood metabolite levels; LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg04013166 chr16:89971882 TCF25 0.62 8.2 0.41 4.97e-15 Skin colour saturation; LIHC trans rs61931739 0.517 rs7975714 chr12:34055611 T/C cg26384229 chr12:38710491 ALG10B 0.51 7.07 0.36 8.59e-12 Morning vs. evening chronotype; LIHC cis rs965469 1.000 rs6051715 chr20:3266548 C/T cg25506879 chr20:3388711 C20orf194 -0.57 -6.96 -0.35 1.79e-11 IFN-related cytopenia; LIHC cis rs35110281 0.782 rs7282933 chr21:45046988 A/G cg01579765 chr21:45077557 HSF2BP -0.35 -6.58 -0.34 1.72e-10 Mean corpuscular volume; LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg27166718 chr6:118880109 PLN;C6orf204 0.53 7.04 0.36 1.07e-11 Diastolic blood pressure; LIHC cis rs7615952 0.932 rs13325495 chr3:125637416 T/G cg05084668 chr3:125655381 ALG1L -0.6 -8.4 -0.41 1.18e-15 Blood pressure (smoking interaction); LIHC cis rs6088580 0.634 rs6059897 chr20:33113224 A/G cg08999081 chr20:33150536 PIGU 0.67 13.27 0.58 1.01e-32 Glomerular filtration rate (creatinine); LIHC cis rs9837602 0.529 rs1087198 chr3:99524381 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.97 0.35 1.59e-11 Breast cancer; LIHC cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg11062466 chr8:58055876 NA 0.4 5.82 0.3 1.37e-8 Developmental language disorder (linguistic errors); LIHC cis rs17739167 0.550 rs4924589 chr15:42229632 C/T cg20935245 chr15:42234343 EHD4 0.4 7.52 0.38 4.99e-13 Monocyte count; LIHC cis rs599083 0.530 rs686921 chr11:68170833 G/T cg01657329 chr11:68192670 LRP5 0.58 7.85 0.39 5.26e-14 Bone mineral density (spine); LIHC cis rs3096299 0.933 rs3096297 chr16:89453155 T/G cg08392591 chr16:89556376 ANKRD11 0.41 6.12 0.31 2.59e-9 Multiple myeloma (IgH translocation); LIHC cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.75 0.39 1.03e-13 Obesity-related traits; LIHC cis rs8180040 0.966 rs12636851 chr3:47463567 C/T cg27129171 chr3:47204927 SETD2 0.59 10.21 0.48 1.5e-21 Colorectal cancer; LIHC cis rs10256972 0.684 rs2363279 chr7:1096143 A/G cg07308232 chr7:1071921 C7orf50 -0.57 -9.24 -0.45 2.78e-18 Longevity;Endometriosis; LIHC cis rs853679 0.517 rs9368554 chr6:28082711 T/C cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs6546550 0.901 rs12232914 chr2:70117176 C/T cg02498382 chr2:70120550 SNRNP27 -0.46 -7.79 -0.39 8.33e-14 Prevalent atrial fibrillation; LIHC cis rs3768617 0.510 rs3768621 chr1:183090057 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs7520050 0.778 rs2991985 chr1:46080530 T/C cg24296786 chr1:45957014 TESK2 0.43 6.46 0.33 3.59e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2439831 1.000 rs561863 chr15:43761352 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.59 0.59 6.27e-34 Lung cancer in ever smokers; LIHC cis rs55665837 0.701 rs12286408 chr11:14579376 G/A cg16394018 chr11:14927549 NA 0.42 5.9 0.3 8.89e-9 Vitamin D levels; LIHC cis rs2932538 0.885 rs3762335 chr1:113100548 C/T cg22162597 chr1:113214053 CAPZA1 0.7 10.72 0.5 2.69e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs847851 0.617 rs9394267 chr6:34960760 C/T cg13137465 chr6:34857473 ANKS1A -0.67 -7.49 -0.38 6.1e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs365132 0.875 rs353476 chr5:176424035 A/G cg16309518 chr5:176445507 NA -0.53 -10.11 -0.48 3.39e-21 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs1707322 1.000 rs6687301 chr1:46382852 T/C cg06784218 chr1:46089804 CCDC17 0.34 6.03 0.31 4.19e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7246657 0.943 rs4417644 chr19:37852472 A/G cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs4478037 0.822 rs9868526 chr3:33124269 A/G cg16652328 chr3:33138982 GLB1;TMPPE 0.54 7.08 0.36 8.33e-12 Major depressive disorder; LIHC cis rs2070488 0.965 rs7640050 chr3:38525864 A/C cg24069376 chr3:38537580 EXOG 0.43 7.97 0.4 2.39e-14 Electrocardiographic conduction measures; LIHC cis rs35110281 0.782 rs7282933 chr21:45046988 A/G cg04455712 chr21:45112962 RRP1B 0.47 7.85 0.39 5.34e-14 Mean corpuscular volume; LIHC cis rs4665809 0.938 rs6742226 chr2:26342537 A/G cg27170947 chr2:26402098 FAM59B -0.67 -8.51 -0.42 5.47e-16 Gut microbiome composition (summer); LIHC cis rs9790314 0.586 rs1811483 chr3:161130900 A/G cg17135325 chr3:160939158 NMD3 0.51 7.64 0.38 2.24e-13 Morning vs. evening chronotype; LIHC cis rs780096 0.546 rs35073769 chr2:27731376 C/T cg27432699 chr2:27873401 GPN1 -0.61 -8.94 -0.44 2.56e-17 Total body bone mineral density; LIHC cis rs60871478 0.947 rs4074610 chr7:791755 G/A cg13844804 chr7:814759 HEATR2 0.43 5.75 0.3 1.95e-8 Cerebrospinal P-tau181p levels; LIHC cis rs1577917 0.559 rs1173418 chr6:86402916 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.69 0.43 1.51e-16 Response to antipsychotic treatment; LIHC cis rs9303401 0.659 rs12940212 chr17:56674474 T/C cg10487724 chr17:56770010 TEX14;RAD51C 1.01 14.01 0.6 1.53e-35 Cognitive test performance; LIHC cis rs10242455 0.557 rs77997620 chr7:99070415 G/T cg18809830 chr7:99032528 PTCD1 -0.83 -6.45 -0.33 3.72e-10 Blood metabolite levels; LIHC cis rs921968 0.541 rs593888 chr2:219427597 A/G cg02176678 chr2:219576539 TTLL4 0.53 7.45 0.37 7.49e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs116095464 0.558 rs9688136 chr5:229348 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs4819052 0.851 rs28501512 chr21:46676702 C/T cg22633049 chr21:46681294 NA -0.36 -6.13 -0.31 2.47e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7249142 0.561 rs4808185 chr19:19296217 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.46 -7.78 -0.39 8.59e-14 IgG glycosylation; LIHC cis rs72653721 0.838 rs3798710 chr6:11002783 C/G cg13562911 chr6:11044106 ELOVL2 0.5 7.24 0.36 2.97e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs929354 0.772 rs6459741 chr7:157014553 G/T cg17757837 chr7:157058334 UBE3C 0.74 12.05 0.55 4.28e-28 Body mass index; LIHC cis rs9503598 0.502 rs9405203 chr6:3433846 G/T cg00476032 chr6:3446245 SLC22A23 -0.32 -5.8 -0.3 1.52e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs6973256 0.605 rs13237435 chr7:133347570 C/T cg10665199 chr7:133106180 EXOC4 -0.34 -5.83 -0.3 1.29e-8 Intelligence (multi-trait analysis); LIHC cis rs7223966 1.000 rs9895920 chr17:61852719 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 7.04 0.36 1.08e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs10089 1.000 rs4836366 chr5:127482494 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.74 0.34 6.56e-11 Ileal carcinoids; LIHC cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg02290350 chr8:58132656 NA 0.42 8.58 0.42 3.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.745 rs7483456 chr11:49774613 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.85 0.35 3.39e-11 Height; LIHC cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 8.79 0.43 7.16e-17 Platelet count; LIHC cis rs12887734 0.524 rs12888002 chr14:104238647 T/C cg08213375 chr14:104286397 PPP1R13B 0.53 9.11 0.44 6.88e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg00280220 chr17:61926910 NA 0.43 6.83 0.35 3.79e-11 Prudent dietary pattern; LIHC cis rs875971 0.929 rs778682 chr7:65837934 A/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC trans rs7618501 1.000 rs6785549 chr3:49736565 G/A cg21659725 chr3:3221576 CRBN -0.97 -19.09 -0.72 7.74e-56 Intelligence (multi-trait analysis); LIHC cis rs13161895 1.000 rs27018 chr5:179405144 A/G cg02702477 chr5:179499311 RNF130 0.75 10.39 0.49 3.62e-22 LDL cholesterol; LIHC cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg19318889 chr4:1322082 MAEA 0.39 6.36 0.33 6.59e-10 Obesity-related traits; LIHC cis rs172166 0.694 rs188105 chr6:28071393 C/T cg25329415 chr6:28076851 NA 0.27 5.71 0.3 2.44e-8 Cardiac Troponin-T levels; LIHC cis rs7534824 0.543 rs72734254 chr1:101382039 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.62 7.06 0.36 9.27e-12 Refractive astigmatism; LIHC cis rs644799 0.965 rs565771 chr11:95644179 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 16.48 0.67 2.63e-45 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6912958 0.754 rs7762864 chr6:88236213 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.88 -0.39 4.44e-14 Monocyte percentage of white cells; LIHC cis rs9910055 0.552 rs4793084 chr17:42317371 G/T cg19774624 chr17:42201019 HDAC5 0.45 6.4 0.33 5.02e-10 Total body bone mineral density; LIHC cis rs875971 0.862 rs880166 chr7:65670762 T/C cg18876405 chr7:65276391 NA -0.37 -6.53 -0.33 2.41e-10 Aortic root size; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg23782820 chr8:58130467 NA 0.33 5.95 0.31 6.66e-9 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.895 rs7782806 chr7:65657897 C/T cg18876405 chr7:65276391 NA -0.36 -6.37 -0.33 5.93e-10 Aortic root size; LIHC cis rs2832191 0.716 rs1888440 chr21:30454484 C/T cg24692254 chr21:30365293 RNF160 0.87 15.63 0.65 6.4e-42 Dental caries; LIHC cis rs559928 0.593 rs112275221 chr11:63936994 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 6.62 0.34 1.36e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg26818010 chr10:134567672 INPP5A -0.7 -9.16 -0.44 4.91e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs240764 0.717 rs10872622 chr6:101165017 C/T cg09795085 chr6:101329169 ASCC3 -0.47 -6.86 -0.35 3.28e-11 Neuroticism; LIHC cis rs2842992 0.872 rs2758330 chr6:160104844 G/T cg26839252 chr6:160211577 TCP1;MRPL18 0.35 5.98 0.31 5.54e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs12586317 0.511 rs113770696 chr14:35444383 C/T cg05294307 chr14:35346193 BAZ1A -0.47 -6.93 -0.35 2.15e-11 Psoriasis; LIHC cis rs7918232 0.941 rs788210 chr10:27476948 T/C cg14240646 chr10:27532245 ACBD5 0.69 6.4 0.33 5.12e-10 Breast cancer; LIHC cis rs6088580 0.634 rs6088512 chr20:33095891 G/A cg08999081 chr20:33150536 PIGU 0.68 13.52 0.59 1.12e-33 Glomerular filtration rate (creatinine); LIHC cis rs1577917 0.545 rs9450325 chr6:86475814 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.32 5.9 0.3 8.77e-9 Response to antipsychotic treatment; LIHC cis rs9534288 0.797 rs9534287 chr13:46603926 A/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs1005277 0.579 rs2472175 chr10:38382901 T/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs11532322 1 rs11532322 chr12:123731423 A/G cg00376283 chr12:123451042 ABCB9 0.69 10.45 0.49 2.36e-22 Schizophrenia; LIHC trans rs61931739 0.500 rs7311284 chr12:34478477 C/G cg26384229 chr12:38710491 ALG10B 0.8 9.89 0.47 1.85e-20 Morning vs. evening chronotype; LIHC cis rs2625529 0.590 rs2856929 chr15:72496762 T/C cg16672083 chr15:72433130 SENP8 -0.31 -5.84 -0.3 1.24e-8 Red blood cell count; LIHC cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg03806693 chr22:41940476 POLR3H 1.12 12.8 0.57 6.57e-31 Vitiligo; LIHC trans rs61931739 0.517 rs11052980 chr12:34036036 T/C cg26384229 chr12:38710491 ALG10B 0.43 6.08 0.31 3.16e-9 Morning vs. evening chronotype; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg12419862 chr22:24373484 LOC391322 0.71 9.82 0.47 3.3e-20 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs2479724 0.870 rs6913232 chr6:41915143 C/T cg17623882 chr6:41773611 USP49 0.51 7.6 0.38 2.81e-13 Menarche (age at onset); LIHC cis rs240764 0.621 rs11155623 chr6:101184373 A/G cg09795085 chr6:101329169 ASCC3 -0.54 -7.76 -0.39 9.98e-14 Neuroticism; LIHC trans rs916888 0.773 rs169201 chr17:44790203 A/G cg26692224 chr17:62915920 LRRC37A3 -0.72 -6.82 -0.35 4.04e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9393692 0.905 rs7450556 chr6:26299900 C/T cg13736514 chr6:26305472 NA -0.38 -6.37 -0.33 6.1e-10 Educational attainment; LIHC cis rs7582180 0.652 rs4851307 chr2:100971778 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.46 0.42 8e-16 Intelligence (multi-trait analysis); LIHC cis rs10927875 0.722 rs6660685 chr1:16346988 A/G cg21385522 chr1:16154831 NA 0.72 9.38 0.45 9.41e-19 Dilated cardiomyopathy; LIHC cis rs2576037 0.796 rs2247021 chr18:44578794 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.48 7.3 0.37 2e-12 Personality dimensions; LIHC cis rs7520050 0.966 rs4134386 chr1:46395089 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.37e-8 Red blood cell count;Reticulocyte count; LIHC cis rs17428076 0.836 rs57718990 chr2:172662614 T/G cg13550731 chr2:172543902 DYNC1I2 0.41 6.7 0.34 8.7e-11 Myopia; LIHC cis rs7927592 0.956 rs948315 chr11:68309140 T/C cg01657329 chr11:68192670 LRP5 -0.47 -6.15 -0.32 2.14e-9 Total body bone mineral density; LIHC cis rs6964587 1.000 rs2188154 chr7:91595138 T/A cg17063962 chr7:91808500 NA 1.02 19.55 0.73 1.15e-57 Breast cancer; LIHC cis rs9457247 0.663 rs2237274 chr6:167442995 C/G cg12798992 chr6:167411361 FGFR1OP 0.45 6.94 0.35 2.01e-11 Crohn's disease; LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg24209194 chr3:40518798 ZNF619 0.63 9.71 0.46 7.86e-20 Renal cell carcinoma; LIHC cis rs208520 0.586 rs208442 chr6:66900618 T/A cg07460842 chr6:66804631 NA -0.46 -5.73 -0.3 2.17e-8 Exhaled nitric oxide output; LIHC cis rs9790314 0.663 rs4557202 chr3:160820524 G/C cg03342759 chr3:160939853 NMD3 -0.73 -11.04 -0.51 1.94e-24 Morning vs. evening chronotype; LIHC cis rs3793683 0.965 rs3829131 chr10:134564627 A/G cg27286337 chr10:134555280 INPP5A -1.05 -19.69 -0.73 3.11e-58 Migraine; LIHC trans rs11165623 0.765 rs12749081 chr1:96970371 A/C cg10631902 chr5:14652156 NA -0.31 -7.15 -0.36 5.16e-12 Hip circumference;Waist circumference; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg07998290 chr8:9912305 MSRA -0.56 -6.19 -0.32 1.7e-9 Preeclampsia; LIHC trans rs208515 0.525 rs10944859 chr6:66665197 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.83 0.43 5.5e-17 Exhaled nitric oxide levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11427898 chr15:38544983 SPRED1 -0.43 -6.44 -0.33 4.09e-10 Pancreatic cancer; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25300318 chr2:200527297 NA 0.43 6.54 0.33 2.24e-10 Immature fraction of reticulocytes; LIHC cis rs9916302 0.904 rs8065963 chr17:37681332 C/T cg00129232 chr17:37814104 STARD3 -0.42 -6.72 -0.34 7.42e-11 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.754 rs2036857 chr4:120249240 T/C cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.02e-25 Corneal astigmatism; LIHC cis rs1801251 0.778 rs2592116 chr2:233735709 G/A cg08000102 chr2:233561755 GIGYF2 -0.71 -10.63 -0.5 5.24e-23 Coronary artery disease; LIHC cis rs9309473 0.950 rs1918863 chr2:73644481 A/G cg20560298 chr2:73613845 ALMS1 -0.52 -6.75 -0.34 6.43e-11 Metabolite levels; LIHC trans rs79976124 0.800 rs6918860 chr6:66637741 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 6.94 0.35 2.03e-11 Type 2 diabetes; LIHC cis rs116095464 0.558 rs56081398 chr5:247318 C/T cg22496380 chr5:211416 CCDC127 -1.15 -10.76 -0.5 1.93e-23 Breast cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12960782 chr5:59996455 DEPDC1B -0.43 -6.87 -0.35 3.12e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg27572855 chr1:25598939 RHD 0.41 8.94 0.44 2.41e-17 Erythrocyte sedimentation rate; LIHC cis rs9649213 0.574 rs3801251 chr7:98027618 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.81 -0.3 1.41e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs7119038 0.730 rs10790269 chr11:118729456 C/T cg19308663 chr11:118741387 NA -0.46 -6.01 -0.31 4.8e-9 Sjögren's syndrome; LIHC cis rs739401 0.572 rs389285 chr11:3062673 G/A cg25174290 chr11:3078921 CARS 0.67 10.26 0.49 1.01e-21 Longevity; LIHC cis rs4800452 0.871 rs9961220 chr18:20733201 G/T cg26136497 chr18:20735537 CABLES1 -0.45 -5.97 -0.31 5.94e-9 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs9790314 0.740 rs4856767 chr3:161004379 C/T cg03342759 chr3:160939853 NMD3 -0.8 -13.08 -0.58 5.8e-32 Morning vs. evening chronotype; LIHC cis rs7917772 0.503 rs7899576 chr10:104307504 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.61 0.56 3.35e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg06873352 chr17:61820015 STRADA 0.75 13.36 0.59 4.89e-33 Prudent dietary pattern; LIHC trans rs743793 0.875 rs5998786 chr22:33575643 G/A cg20274824 chr1:36638199 MAP7D1 0.45 6.38 0.33 5.92e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs7107174 0.892 rs2510038 chr11:77966034 C/T cg02023728 chr11:77925099 USP35 0.49 8.99 0.44 1.78e-17 Testicular germ cell tumor; LIHC cis rs2354432 0.714 rs7531962 chr1:146746023 G/A cg25205988 chr1:146714368 CHD1L -1.02 -16.58 -0.67 1.02e-45 Mitochondrial DNA levels; LIHC cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg09359103 chr1:154839909 KCNN3 -0.29 -5.72 -0.3 2.38e-8 Prostate cancer; LIHC cis rs4478037 0.822 rs3924695 chr3:33122085 C/T cg27203090 chr3:33138513 GLB1;TMPPE -0.5 -6.27 -0.32 1.08e-9 Major depressive disorder; LIHC cis rs79149102 0.737 rs12593975 chr15:75189591 G/A cg16226627 chr15:75307476 SCAMP5 0.43 6.09 0.31 2.95e-9 Lung cancer; LIHC cis rs12144094 0.882 rs55806106 chr1:120232539 T/A cg20995928 chr1:120229863 NA 0.37 6.17 0.32 1.92e-9 Height; LIHC cis rs9911578 0.835 rs9303398 chr17:56484257 T/C cg05425664 chr17:57184151 TRIM37 0.58 8.41 0.41 1.13e-15 Intelligence (multi-trait analysis); LIHC cis rs9814567 0.964 rs6776203 chr3:134234345 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1499614 1.000 rs2707828 chr7:66171377 G/A cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs644799 1.000 rs2508289 chr11:95624669 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.63 8.66 0.42 1.87e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6545883 0.894 rs6760075 chr2:61612881 C/A cg14146966 chr2:61757674 XPO1 -0.44 -7.45 -0.37 7.93e-13 Tuberculosis; LIHC cis rs6570726 0.533 rs1832374 chr6:145717752 A/G cg23711669 chr6:146136114 FBXO30 0.36 5.98 0.31 5.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs55823223 0.564 rs12103594 chr17:73855279 C/T cg10935138 chr17:73851978 WBP2 0.72 9.38 0.45 9.27e-19 Psoriasis; LIHC cis rs4906332 0.811 rs2756138 chr14:103996733 C/G cg04998671 chr14:104000505 TRMT61A 0.57 7.81 0.39 7.23e-14 Coronary artery disease; LIHC cis rs7772486 0.536 rs9373467 chr6:145955605 C/T cg05347473 chr6:146136440 FBXO30 0.42 6.17 0.32 1.95e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.875 rs9390371 chr6:146363180 A/G cg23711669 chr6:146136114 FBXO30 0.6 10.62 0.5 5.84e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs17412740 1.000 rs41343448 chr8:20271413 A/G cg21142257 chr8:20054699 ATP6V1B2 -0.56 -5.98 -0.31 5.58e-9 Preeclampsia; LIHC cis rs67311347 1.000 rs7612015 chr3:40399974 A/C cg00656387 chr3:40428638 ENTPD3 0.41 6.87 0.35 2.97e-11 Renal cell carcinoma; LIHC cis rs10876993 0.928 rs10082911 chr12:58104104 C/A cg18357645 chr12:58087776 OS9 0.51 8.39 0.41 1.3e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs2116941 1.000 rs8104426 chr19:10338676 G/T cg01850179 chr19:10340795 S1PR2 0.57 9.24 0.45 2.68e-18 Pulse pressure; LIHC cis rs8180040 0.620 rs56217494 chr3:47048452 T/G cg27129171 chr3:47204927 SETD2 -0.55 -9.12 -0.44 6.75e-18 Colorectal cancer; LIHC cis rs6747952 0.866 rs4663854 chr2:239083167 C/T cg17459225 chr2:239074497 NA -0.36 -5.83 -0.3 1.26e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs9517313 0.584 rs9556974 chr13:99216302 G/C cg07423050 chr13:99094983 FARP1 -0.49 -8.39 -0.41 1.29e-15 Neuroticism; LIHC cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.85 -0.51 8.78e-24 Platelet count; LIHC cis rs1552244 0.882 rs55808392 chr3:10054681 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.71 9.82 0.47 3.25e-20 Alzheimer's disease; LIHC cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg08067268 chr2:26466485 HADHB;HADHA 0.52 6.84 0.35 3.63e-11 Gut microbiome composition (summer); LIHC cis rs3741798 0.901 rs61922024 chr12:12485881 C/A cg08615371 chr12:12503544 MANSC1 0.98 7.84 0.39 5.9e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs4665809 0.509 rs62128431 chr2:26398116 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 11.48 0.53 5.1e-26 Gut microbiome composition (summer); LIHC cis rs796364 0.760 rs2202922 chr2:200882610 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 8.71 0.43 1.35e-16 Schizophrenia; LIHC cis rs473651 0.935 rs483166 chr2:239346641 C/T cg21699342 chr2:239360505 ASB1 -0.36 -7.05 -0.36 9.96e-12 Multiple system atrophy; LIHC cis rs600806 0.778 rs10494040 chr1:110015732 C/T cg02415029 chr1:110025642 ATXN7L2 -0.44 -5.75 -0.3 1.95e-8 Intelligence (multi-trait analysis); LIHC cis rs4888262 0.526 rs7201105 chr16:74590603 A/G cg01733217 chr16:74700730 RFWD3 0.79 15.09 0.63 8.58e-40 Testicular germ cell tumor; LIHC cis rs1499614 0.803 rs1796229 chr7:66119661 G/A cg12463550 chr7:65579703 CRCP 0.67 6.96 0.35 1.77e-11 Gout; LIHC trans rs2243480 1.000 rs313813 chr7:65503500 C/T cg10756647 chr7:56101905 PSPH 1.09 13.69 0.59 2.59e-34 Diabetic kidney disease; LIHC cis rs5769765 1.000 rs5770728 chr22:50259984 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.11 0.44 7.22e-18 Schizophrenia; LIHC cis rs4713118 0.696 rs2394002 chr6:27748015 G/A cg20933634 chr6:27740509 NA 0.45 5.78 0.3 1.64e-8 Parkinson's disease; LIHC cis rs77633900 0.614 rs1905694 chr15:76951772 T/C cg21673338 chr15:77095150 SCAPER -0.5 -7.39 -0.37 1.11e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs174601 0.861 rs174547 chr11:61570783 C/T cg27386326 chr11:61587980 NA -0.69 -14.72 -0.62 2.36e-38 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs7772486 0.875 rs2814876 chr6:146304030 C/T cg23711669 chr6:146136114 FBXO30 0.67 11.43 0.53 7.55e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs9641123 0.639 rs2528529 chr7:93232328 C/T cg09745688 chr16:2908918 PRSS22 -0.37 -6.41 -0.33 4.76e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs2032447 0.639 rs198810 chr6:26128618 A/G cg03264133 chr6:25882463 NA 0.5 6.33 0.32 7.61e-10 Intelligence (multi-trait analysis); LIHC cis rs6121246 0.529 rs6060171 chr20:30183269 C/T cg13852791 chr20:30311386 BCL2L1 0.7 6.45 0.33 3.83e-10 Mean corpuscular hemoglobin; LIHC cis rs9325144 0.671 rs7485963 chr12:38768254 C/G cg26384229 chr12:38710491 ALG10B -0.56 -7.65 -0.38 2.03e-13 Morning vs. evening chronotype; LIHC cis rs9303280 0.901 rs1008723 chr17:38066267 G/T cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.99 0.31 5.29e-9 Self-reported allergy; LIHC cis rs6570726 0.689 rs411785 chr6:145888398 G/A cg05347473 chr6:146136440 FBXO30 0.4 6.37 0.33 6.1e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11583043 0.957 rs6667932 chr1:101503755 G/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 5.97 0.31 6.04e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.35 -0.45 1.18e-18 Bipolar disorder; LIHC trans rs1814175 0.588 rs10839463 chr11:49971643 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs763121 1.000 rs763121 chr22:38879940 C/T cg06022373 chr22:39101656 GTPBP1 -0.5 -8.51 -0.42 5.35e-16 Menopause (age at onset); LIHC cis rs7044106 0.762 rs966396 chr9:123453281 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.91 0.39 3.61e-14 Hip circumference adjusted for BMI; LIHC cis rs1712517 0.771 rs11191666 chr10:105127278 A/G cg05636881 chr10:105038444 INA 0.48 7.53 0.38 4.62e-13 Migraine; LIHC cis rs2304069 0.954 rs9324638 chr5:149400718 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.94 -12.26 -0.55 6.68e-29 HIV-1 control; LIHC cis rs12744310 0.887 rs67483852 chr1:41784465 C/T cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.92e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg22105103 chr4:187893119 NA 0.35 8.96 0.44 2.08e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs16828019 0.852 rs11209545 chr1:41576357 T/G cg03962019 chr1:41807865 NA 0.5 7.22 0.36 3.33e-12 Intelligence (multi-trait analysis); LIHC cis rs875971 0.862 rs10950043 chr7:65988610 T/C cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.34e-9 Aortic root size; LIHC cis rs4934494 0.768 rs34993776 chr10:91441689 C/T cg19698084 chr10:91461284 KIF20B -0.49 -6.33 -0.32 7.54e-10 Red blood cell count; LIHC cis rs17685 0.753 rs6951943 chr7:75772452 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 8.96 0.44 2.2e-17 Platelet count; LIHC cis rs9611565 0.512 rs5751153 chr22:42156561 T/C cg06634786 chr22:41940651 POLR3H 0.75 7.57 0.38 3.48e-13 Vitiligo; LIHC cis rs7131987 0.683 rs3782511 chr12:29496224 G/A cg00204748 chr12:29376779 FAR2 0.38 6.76 0.34 6.12e-11 QT interval; LIHC cis rs921968 0.643 rs596076 chr2:219451015 T/G cg02985541 chr2:219472218 PLCD4 0.45 8.43 0.41 1.01e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs1348850 0.645 rs10164417 chr2:178444130 A/G cg27490568 chr2:178487706 NA 0.76 9.66 0.46 1.08e-19 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg16049864 chr8:95962084 TP53INP1 -0.6 -11.29 -0.52 2.45e-25 Type 2 diabetes; LIHC cis rs7072216 0.763 rs12259939 chr10:100169021 T/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.34 -0.32 7.28e-10 Metabolite levels; LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg04013166 chr16:89971882 TCF25 0.62 8.43 0.41 9.62e-16 Skin colour saturation; LIHC cis rs11122272 0.701 rs2883799 chr1:231531166 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs4975616 0.804 rs381949 chr5:1322468 G/A cg06550200 chr5:1325588 CLPTM1L -0.66 -10.43 -0.49 2.66e-22 Lung cancer; LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg00800038 chr16:89945340 TCF25 -0.7 -11.13 -0.52 9.55e-25 Skin colour saturation; LIHC cis rs11614062 0.761 rs11107115 chr12:93972987 A/G cg18151635 chr12:93972918 NA -0.53 -8.78 -0.43 8.12e-17 Height; LIHC cis rs919433 0.680 rs2565161 chr2:198285554 C/G cg10820045 chr2:198174542 NA 0.56 9.11 0.44 7.29e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6754311 0.512 rs12998387 chr2:136507039 A/G cg15123519 chr2:136567270 LCT 0.44 8.69 0.43 1.52e-16 Mosquito bite size; LIHC cis rs4727027 0.866 rs3735311 chr7:148877737 T/C cg23583168 chr7:148888333 NA -0.73 -10.36 -0.49 4.51e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs4586057 0.514 rs7905446 chr10:92619161 T/G cg14313238 chr10:92632228 RPP30 0.36 5.99 0.31 5.4e-9 Economic and political preferences (time); LIHC cis rs2412488 1.000 rs11734039 chr4:54264428 T/C cg22241045 chr4:54363911 LNX1 -0.41 -6.71 -0.34 8.19e-11 DNA methylation (variation); LIHC cis rs1707322 1.000 rs1622208 chr1:46498375 A/G cg06784218 chr1:46089804 CCDC17 -0.39 -6.97 -0.35 1.66e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9614461 0.826 rs9614649 chr22:45746097 C/A cg13318129 chr22:45737514 FAM118A 0.54 7.86 0.39 5.11e-14 Tonsillectomy; LIHC cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg27572855 chr1:25598939 RHD 0.38 8.15 0.4 6.96e-15 Erythrocyte sedimentation rate; LIHC cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg10560079 chr2:191398806 TMEM194B 0.51 7.99 0.4 2.03e-14 Pulse pressure; LIHC cis rs546131 0.928 rs552868 chr11:34830694 G/A cg11058730 chr11:34937778 PDHX;APIP 0.62 9.47 0.46 4.67e-19 Lung disease severity in cystic fibrosis; LIHC cis rs12493885 0.818 rs61791544 chr3:153767504 T/A cg10247383 chr3:153839028 SGEF 0.65 6.13 0.31 2.41e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2980436 1 rs2980436 chr8:8092025 A/G cg06636001 chr8:8085503 FLJ10661 -0.55 -8.29 -0.41 2.56e-15 Schizophrenia; LIHC cis rs4689388 0.926 rs10012946 chr4:6293350 C/T cg25554036 chr4:6271136 WFS1 -0.48 -6.98 -0.35 1.55e-11 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs2806561 0.578 rs6702719 chr1:23302576 T/C cg12483005 chr1:23474871 LUZP1 0.43 6.49 0.33 2.97e-10 Height; LIHC cis rs854572 0.600 rs705382 chr7:94955221 C/G cg01874867 chr7:94954059 PON1 -0.42 -7.04 -0.36 1.08e-11 Paraoxonase activity; LIHC cis rs5769765 1.000 rs738711 chr22:50282603 A/G cg02269571 chr22:50332266 NA 0.61 8.64 0.42 2.24e-16 Schizophrenia; LIHC cis rs1046896 0.553 rs1044661 chr17:80901020 G/A cg02711726 chr17:80685570 FN3KRP -0.4 -7.41 -0.37 1.01e-12 Glycated hemoglobin levels; LIHC cis rs72781680 0.898 rs72788214 chr2:24087621 A/C cg08917208 chr2:24149416 ATAD2B 0.88 8.29 0.41 2.69e-15 Lymphocyte counts; LIHC cis rs7727544 0.735 rs272884 chr5:131668654 G/C cg07395648 chr5:131743802 NA -0.3 -6.23 -0.32 1.34e-9 Blood metabolite levels; LIHC cis rs6582630 0.599 rs12309369 chr12:38419683 C/G cg26384229 chr12:38710491 ALG10B -0.46 -6.02 -0.31 4.55e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs9858542 1.000 rs4283605 chr3:49678651 A/G cg03060546 chr3:49711283 APEH -0.63 -8.48 -0.42 6.94e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1419980 0.730 rs11054886 chr12:7772948 C/A cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs826838 1.000 rs10506122 chr12:38699232 A/G cg26384229 chr12:38710491 ALG10B 1.06 14.59 0.62 7.64e-38 Heart rate; LIHC cis rs9517320 1.000 rs12864890 chr13:99126457 T/C cg07423050 chr13:99094983 FARP1 0.38 6.28 0.32 1.04e-9 Longevity; LIHC cis rs2180341 0.842 rs7739679 chr6:127545428 G/A cg27446573 chr6:127587934 RNF146 1.02 14.47 0.62 2.36e-37 Breast cancer; LIHC cis rs4407350 0.870 rs131172 chr22:44902759 A/G cg04154583 chr22:44889756 LDOC1L 0.29 5.75 0.3 1.97e-8 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.659 rs62081315 chr17:56781468 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs11229555 0.645 rs12226725 chr11:58246332 G/A cg15696309 chr11:58395628 NA -0.62 -7.17 -0.36 4.77e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs11098499 0.754 rs34425882 chr4:120253177 G/A cg25214090 chr10:38739885 LOC399744 0.5 8.13 0.4 7.9e-15 Corneal astigmatism; LIHC trans rs1814175 0.646 rs1722010 chr11:49897958 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs1018836 0.828 rs10091275 chr8:91559751 A/G cg16814680 chr8:91681699 NA -0.54 -8.36 -0.41 1.62e-15 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.27 0.32 1.08e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg13409248 chr3:40428643 ENTPD3 0.49 8.21 0.41 4.7e-15 Renal cell carcinoma; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg05185784 chr16:90016020 DEF8 -0.48 -6.43 -0.33 4.38e-10 Skin colour saturation; LIHC trans rs12752401 0.717 rs12751268 chr1:103002533 C/T cg24921808 chr19:740313 PALM 0.48 6.35 0.32 6.81e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs2239547 0.657 rs7638524 chr3:52874861 G/A cg11645453 chr3:52864694 ITIH4 0.36 9.36 0.45 1.09e-18 Schizophrenia; LIHC cis rs752010 0.746 rs10890146 chr1:42089389 G/A cg06885757 chr1:42089581 HIVEP3 0.33 6.8 0.35 4.66e-11 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs4819052 0.851 rs8133045 chr21:46658137 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.39 0.52 1.11e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7914558 0.966 rs10748836 chr10:104693917 G/A cg15744005 chr10:104629667 AS3MT -0.4 -9.11 -0.44 7e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg04267008 chr7:1944627 MAD1L1 -0.59 -9.33 -0.45 1.37e-18 Schizophrenia; LIHC cis rs8063160 0.799 rs1805007 chr16:89986117 A/G cg07984980 chr16:89898383 SPIRE2 -0.73 -5.71 -0.3 2.39e-8 Red vs non-red hair color;Light vs. dark hair color;Brown vs. non-brown hair color; LIHC cis rs61776719 0.875 rs10890238 chr1:38445654 A/T cg18451016 chr1:38461880 NA 0.38 6.06 0.31 3.69e-9 Coronary artery disease; LIHC cis rs7945718 0.591 rs4515952 chr11:12690200 G/A cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs1707322 0.893 rs9919275 chr1:46441360 A/C cg06784218 chr1:46089804 CCDC17 0.36 6.55 0.33 2.13e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8062405 1.000 rs8062405 chr16:28837906 C/T cg07451762 chr16:28383216 NA -0.32 -6.13 -0.31 2.47e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1568889 1.000 rs7934085 chr11:28369660 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.85 0.35 3.37e-11 Bipolar disorder; LIHC cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg14983838 chr19:29218262 NA 0.48 7.87 0.39 4.59e-14 Methadone dose in opioid dependence; LIHC cis rs2404602 0.716 rs12440815 chr15:76627328 C/A cg03037974 chr15:76606532 NA 0.91 19.73 0.73 2.06e-58 Blood metabolite levels; LIHC cis rs8180040 1.000 rs295449 chr3:47375955 G/A cg02527881 chr3:46936655 PTH1R -0.3 -5.87 -0.3 1.04e-8 Colorectal cancer; LIHC cis rs6912958 0.535 rs1753154 chr6:88032843 G/C cg12350822 chr6:88032061 C6orf162;GJB7 0.36 7.05 0.36 1.02e-11 Monocyte percentage of white cells; LIHC cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg13607699 chr17:42295918 UBTF -0.45 -7.11 -0.36 6.75e-12 Total body bone mineral density; LIHC cis rs2991971 0.933 rs12568144 chr1:45965307 G/A cg15605315 chr1:45957053 TESK2 0.47 6.62 0.34 1.38e-10 High light scatter reticulocyte count; LIHC cis rs7512552 0.809 rs9436112 chr1:150406449 A/C cg15654264 chr1:150340011 RPRD2 0.69 11.26 0.52 3.09e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs561341 0.883 rs7406056 chr17:30220224 C/T cg20587970 chr11:113659929 NA -0.73 -8.32 -0.41 2.12e-15 Hip circumference adjusted for BMI; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg01390039 chr16:89315293 NA 0.43 6.14 0.32 2.25e-9 Bilirubin levels; LIHC cis rs4713118 0.955 rs9393848 chr6:27688369 C/T cg20933634 chr6:27740509 NA 0.47 6.34 0.32 7.46e-10 Parkinson's disease; LIHC cis rs11190604 0.767 rs10786590 chr10:102164604 T/C cg07080220 chr10:102295463 HIF1AN 0.46 6.35 0.32 7.05e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7959663 1 rs7959663 chr12:109884367 G/C cg05360138 chr12:110035743 NA 0.72 8.35 0.41 1.74e-15 Bipolar disorder lithium response (categorical) or schizophrenia; LIHC trans rs6762477 0.748 rs9831967 chr3:50217234 C/T cg21659725 chr3:3221576 CRBN -0.57 -9.07 -0.44 9.85e-18 Menarche (age at onset); LIHC cis rs2404602 0.532 rs12591100 chr15:76700801 C/A cg03037974 chr15:76606532 NA -0.64 -11.92 -0.54 1.24e-27 Blood metabolite levels; LIHC cis rs7662987 0.517 rs1133485 chr4:100023811 T/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs2070433 0.749 rs718496 chr21:47904585 A/C cg12379764 chr21:47803548 PCNT 0.6 8.8 0.43 6.94e-17 Lymphocyte counts; LIHC trans rs3960554 0.709 rs56163935 chr7:75788744 T/C cg19862616 chr7:65841803 NCRNA00174 0.61 8.31 0.41 2.31e-15 Eotaxin levels; LIHC cis rs7100689 0.646 rs1815650 chr10:82157464 C/T cg01528321 chr10:82214614 TSPAN14 0.65 9.88 0.47 1.98e-20 Post bronchodilator FEV1; LIHC cis rs7100689 0.577 rs2282367 chr10:82040346 A/G cg01528321 chr10:82214614 TSPAN14 0.93 12.42 0.56 1.67e-29 Post bronchodilator FEV1; LIHC cis rs1801251 1.000 rs283480 chr2:233648742 G/A cg25237894 chr2:233734115 C2orf82 0.57 11.04 0.51 1.86e-24 Coronary artery disease; LIHC cis rs8014671 0.597 rs8021180 chr14:70783943 A/G cg25576086 chr14:70833871 SYNJ2BP -0.57 -10.51 -0.49 1.45e-22 Prostate cancer; LIHC cis rs9326248 0.581 rs10892076 chr11:116988936 G/A cg01368799 chr11:117014884 PAFAH1B2 0.63 9.55 0.46 2.51e-19 Blood protein levels; LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg22963979 chr7:1858916 MAD1L1 -0.44 -7.18 -0.36 4.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs2257205 0.588 rs7219856 chr17:56941020 C/T cg12560992 chr17:57184187 TRIM37 0.67 7.28 0.37 2.36e-12 Pancreatic cancer; LIHC cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs7613875 0.620 rs2526747 chr3:50082914 C/G cg21467203 chr3:49911342 NA -0.5 -8.86 -0.43 4.39e-17 Body mass index; LIHC cis rs4665809 0.941 rs3177055 chr2:26359315 G/A cg27170947 chr2:26402098 FAM59B -0.66 -8.21 -0.41 4.43e-15 Gut microbiome composition (summer); LIHC cis rs4243830 0.850 rs12760251 chr1:6601336 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.84 -10.59 -0.5 7.56e-23 Body mass index; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.31 0.52 2.11e-25 Prudent dietary pattern; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg08122386 chr6:26195954 NA 0.54 5.98 0.31 5.6e-9 Gout;Renal underexcretion gout; LIHC cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg02969873 chr4:1330999 MAEA -0.41 -6.3 -0.32 9.07e-10 Longevity; LIHC cis rs8177179 0.967 rs4994582 chr3:133437566 G/C cg24879335 chr3:133465180 TF 0.46 10.69 0.5 3.32e-23 Iron status biomarkers (transferrin levels); LIHC cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg19774624 chr17:42201019 HDAC5 -0.81 -12.62 -0.56 3.08e-30 Total body bone mineral density; LIHC cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg06634786 chr22:41940651 POLR3H 0.79 9.1 0.44 7.43e-18 Vitiligo; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg07677032 chr17:61819896 STRADA 0.43 6.2 0.32 1.62e-9 Prudent dietary pattern; LIHC cis rs10791323 0.604 rs2257010 chr11:133712348 G/A cg06766960 chr11:133703094 NA -0.66 -11.04 -0.51 1.94e-24 Childhood ear infection; LIHC cis rs57590327 0.503 rs11706976 chr3:81899653 C/T cg07356753 chr3:81810745 GBE1 -0.52 -7.88 -0.39 4.46e-14 Extraversion; LIHC cis rs6690583 0.623 rs6672362 chr1:85454881 C/G cg22153463 chr1:85462885 MCOLN2 0.5 6.03 0.31 4.19e-9 Serum sulfate level; LIHC cis rs7937890 0.559 rs1548074 chr11:14534825 A/G cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg02953397 chr1:1238678 ACAP3 0.3 6.27 0.32 1.07e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1559088 0.847 rs2287680 chr19:33608566 A/G cg17764715 chr19:33622953 WDR88 -0.47 -6.93 -0.35 2.09e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs12931792 0.846 rs9924308 chr16:30154740 C/T cg17640201 chr16:30407289 ZNF48 -0.37 -5.82 -0.3 1.36e-8 Tonsillectomy; LIHC cis rs13394619 0.775 rs10165819 chr2:11722102 A/T cg07314298 chr2:11723111 GREB1 -0.5 -9.68 -0.46 9.57e-20 Endometriosis; LIHC cis rs17666538 0.535 rs4338080 chr8:615598 A/G cg02524346 chr8:600233 NA 0.78 5.96 0.31 6.3e-9 IgG glycosylation; LIHC cis rs7208859 0.623 rs8067035 chr17:29102188 T/C cg14067834 chr17:29058358 SUZ12P 0.74 7.49 0.38 5.97e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg19318889 chr4:1322082 MAEA 0.64 10.41 0.49 3.23e-22 Longevity; LIHC cis rs11991744 0.510 rs7464171 chr8:124660335 G/A cg22342100 chr8:124666123 KLHL38 -0.37 -5.93 -0.31 7.28e-9 Electrocardiographic traits; LIHC cis rs881375 0.967 rs10733648 chr9:123700779 A/G cg14580859 chr9:123691850 NA 0.38 6.9 0.35 2.6e-11 Rheumatoid arthritis; LIHC cis rs7762018 1.000 rs7746598 chr6:170084933 T/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.52 6.02 0.31 4.52e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg25072359 chr17:41440525 NA 0.38 6.03 0.31 4.34e-9 Menopause (age at onset); LIHC cis rs1712517 0.771 rs7921655 chr10:105113701 C/T cg05636881 chr10:105038444 INA 0.49 7.59 0.38 3e-13 Migraine; LIHC cis rs9818758 0.607 rs34326553 chr3:49134429 A/G cg06212747 chr3:49208901 KLHDC8B -0.66 -5.81 -0.3 1.45e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg10360323 chr17:41437877 NA 0.4 5.95 0.31 6.7e-9 Menopause (age at onset); LIHC cis rs10870270 1.000 rs7098014 chr10:133775029 G/A cg08754478 chr10:133766260 PPP2R2D -0.55 -8.13 -0.4 8.04e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9611565 0.512 rs6002474 chr22:42168181 A/G cg03806693 chr22:41940476 POLR3H 0.97 10.19 0.48 1.76e-21 Vitiligo; LIHC cis rs2279817 0.863 rs13376033 chr1:18016590 A/G cg21791023 chr1:18019539 ARHGEF10L -0.68 -7.99 -0.4 2.06e-14 Neuroticism; LIHC cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg03351412 chr1:154909251 PMVK -0.71 -10.76 -0.5 1.87e-23 Prostate cancer; LIHC cis rs875971 1.000 rs12533997 chr7:65965377 A/G cg18252515 chr7:66147081 NA -0.43 -6.02 -0.31 4.43e-9 Aortic root size; LIHC cis rs7224737 1.000 rs2240010 chr17:40278081 T/A cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.22e-9 Fibrinogen levels; LIHC cis rs7534824 0.625 rs61780321 chr1:101428304 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 6.73 0.34 7.3e-11 Refractive astigmatism; LIHC cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg05368731 chr17:41323189 NBR1 0.72 12.35 0.56 3.17e-29 Menopause (age at onset); LIHC cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.24 -0.36 3.08e-12 Diabetic kidney disease; LIHC cis rs7927592 0.913 rs59056571 chr11:68272973 T/G cg01657329 chr11:68192670 LRP5 -0.46 -5.97 -0.31 6.09e-9 Total body bone mineral density; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.655 rs9638973 chr7:1133678 A/G cg09177884 chr7:1199841 ZFAND2A -0.53 -6.24 -0.32 1.29e-9 Bronchopulmonary dysplasia; LIHC cis rs12980942 0.810 rs8103839 chr19:41781493 C/G cg25627403 chr19:41769009 HNRNPUL1 0.57 7.01 0.35 1.27e-11 Coronary artery disease; LIHC cis rs11030122 0.632 rs10835556 chr11:4083013 A/G cg18678763 chr11:4115507 RRM1 -0.58 -8.58 -0.42 3.28e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs17401966 0.838 rs946502 chr1:10309279 G/C cg19773385 chr1:10388646 KIF1B -0.4 -7.36 -0.37 1.4e-12 Hepatocellular carcinoma; LIHC cis rs17213078 0.505 rs737101 chr2:106732545 C/T cg16099169 chr2:106886729 NA 0.41 6.33 0.32 7.55e-10 Facial morphology (factor 23); LIHC cis rs1005277 0.579 rs2505248 chr10:38459097 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.95 -0.31 6.46e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4423214 0.959 rs11233747 chr11:71171642 G/A cg24826892 chr11:71159390 DHCR7 0.48 6.16 0.32 1.99e-9 Vitamin D levels; LIHC cis rs9814567 1.000 rs7427492 chr3:134261654 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9902453 0.967 rs4429345 chr17:28458105 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.6 -9.41 -0.45 7.5e-19 Coffee consumption (cups per day); LIHC trans rs11039798 0.925 rs10769373 chr11:48531980 T/A cg15704280 chr7:45808275 SEPT13 0.62 6.36 0.33 6.65e-10 Axial length; LIHC cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7914558 0.966 rs12571568 chr10:104891396 C/G cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg02564969 chr6:151773285 C6orf211;RMND1 -0.51 -7.03 -0.36 1.1e-11 Menarche (age at onset); LIHC cis rs240764 0.548 rs12206838 chr6:101180128 G/A cg09795085 chr6:101329169 ASCC3 -0.45 -6.61 -0.34 1.49e-10 Neuroticism; LIHC trans rs61931739 0.500 rs3924705 chr12:34557825 A/T cg26384229 chr12:38710491 ALG10B 0.63 8.01 0.4 1.76e-14 Morning vs. evening chronotype; LIHC cis rs12701220 0.655 rs7778968 chr7:1144622 C/G cg16145915 chr7:1198662 ZFAND2A -0.33 -6.56 -0.33 2.02e-10 Bronchopulmonary dysplasia; LIHC cis rs11098499 0.754 rs9991959 chr4:120253773 C/T cg09307838 chr4:120376055 NA -0.71 -11.03 -0.51 2.12e-24 Corneal astigmatism; LIHC cis rs9811920 0.609 rs7638900 chr3:99670773 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 7.16 0.36 4.94e-12 Axial length; LIHC cis rs10242455 0.702 rs2293256 chr7:99057701 A/G cg18809830 chr7:99032528 PTCD1 0.66 6.05 0.31 3.89e-9 Blood metabolite levels; LIHC cis rs2257205 0.667 rs16943134 chr17:56681389 A/G cg05425664 chr17:57184151 TRIM37 -0.61 -6.69 -0.34 8.94e-11 Pancreatic cancer; LIHC cis rs1801251 1.000 rs2675971 chr2:233726154 A/G cg08000102 chr2:233561755 GIGYF2 -0.76 -11.48 -0.53 5.13e-26 Coronary artery disease; LIHC cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg25072359 chr17:41440525 NA 0.37 5.83 0.3 1.3e-8 Menopause (age at onset); LIHC cis rs9470361 0.506 rs4568449 chr6:36621143 A/G cg08179530 chr6:36648295 CDKN1A 0.42 6.29 0.32 9.6e-10 QRS complex (Cornell);QRS duration;Left ventricular fractional shortening; LIHC cis rs6456156 0.586 rs13195158 chr6:167481392 G/A cg12798992 chr6:167411361 FGFR1OP 0.43 6.6 0.34 1.59e-10 Primary biliary cholangitis; LIHC cis rs12908161 0.920 rs35738019 chr15:85280210 T/C cg12863693 chr15:85201151 NMB 0.47 6.76 0.34 5.88e-11 Schizophrenia; LIHC cis rs2204008 0.653 rs11182569 chr12:38572452 G/A cg13010199 chr12:38710504 ALG10B 0.58 6.89 0.35 2.62e-11 Bladder cancer; LIHC cis rs12744310 0.887 rs17362424 chr1:41794403 A/C cg03962019 chr1:41807865 NA -0.4 -6.04 -0.31 4.06e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2742417 0.603 rs9826208 chr3:45773991 C/T cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg21782813 chr7:2030301 MAD1L1 0.56 10.24 0.48 1.22e-21 Autism spectrum disorder or schizophrenia; LIHC cis rs7078219 0.505 rs41290504 chr10:101293035 C/A cg06854084 chr10:101292507 NKX2-3 -0.33 -6.09 -0.31 3.11e-9 Dental caries; LIHC cis rs4654899 1.000 rs6684976 chr1:21367501 G/A cg08539965 chr1:21396338 EIF4G3 0.33 5.74 0.3 2.07e-8 Superior frontal gyrus grey matter volume; LIHC cis rs2404602 0.692 rs55864032 chr15:77122548 A/G cg03037974 chr15:76606532 NA 0.74 14.63 0.62 5.72e-38 Blood metabolite levels; LIHC trans rs875971 1.000 rs10244498 chr7:66116056 A/G cg10756647 chr7:56101905 PSPH 0.47 7.06 0.36 9.12e-12 Aortic root size; LIHC cis rs1670533 1.000 rs4690215 chr4:1054619 G/C cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC trans rs459571 0.876 rs2520095 chr9:136919568 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.56 -8.58 -0.42 3.32e-16 Platelet distribution width; LIHC cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg15691649 chr6:25882328 NA -0.53 -7.65 -0.38 2.07e-13 Blood metabolite levels; LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg18279126 chr7:2041391 MAD1L1 0.36 6.04 0.31 4.12e-9 Bipolar disorder and schizophrenia; LIHC cis rs9381040 0.610 rs2294694 chr6:41046177 G/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.79 -0.3 1.58e-8 Alzheimer's disease (late onset); LIHC cis rs798554 0.634 rs6970963 chr7:2821271 C/T cg13628971 chr7:2884303 GNA12 0.42 6.7 0.34 8.72e-11 Height; LIHC cis rs6788895 1.000 rs41354246 chr3:150524636 G/T cg09723797 chr3:150481914 SIAH2 0.57 7.11 0.36 6.67e-12 Breast cancer; LIHC cis rs826838 1.000 rs1393537 chr12:38920961 C/T cg13010199 chr12:38710504 ALG10B 0.6 7.29 0.37 2.21e-12 Heart rate; LIHC cis rs4586057 0.533 rs4933618 chr10:92652571 C/T cg14313238 chr10:92632228 RPP30 0.36 6.06 0.31 3.55e-9 Economic and political preferences (time); LIHC cis rs10751667 0.643 rs10902234 chr11:935578 A/G cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.56e-13 Alzheimer's disease (late onset); LIHC cis rs1371867 0.875 rs1962901 chr8:101326428 A/G cg06636551 chr8:101224915 SPAG1 -0.47 -8.71 -0.43 1.34e-16 Atrioventricular conduction; LIHC cis rs4665809 1.000 rs4665819 chr2:26309073 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.99 -0.44 1.69e-17 Gut microbiome composition (summer); LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.59 9.01 0.44 1.44e-17 Height; LIHC cis rs6893300 0.506 rs35320050 chr5:179131013 C/T cg14593053 chr5:179126677 CANX 0.44 8.06 0.4 1.28e-14 Resting heart rate; LIHC cis rs10751667 0.666 rs6597960 chr11:977036 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs35365539 1 rs35365539 chr3:49794347 A/AC cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Blood protein levels; LIHC trans rs4566357 0.557 rs2272201 chr2:227912551 T/A cg16088116 chr21:44841560 SIK1 -0.4 -6.23 -0.32 1.4e-9 Coronary artery disease; LIHC cis rs9790314 0.540 rs35462273 chr3:160991877 C/T cg17135325 chr3:160939158 NMD3 0.53 7.5 0.38 5.58e-13 Morning vs. evening chronotype; LIHC cis rs7772486 0.875 rs9373485 chr6:146401429 A/T cg23711669 chr6:146136114 FBXO30 0.64 10.93 0.51 4.87e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs1448094 0.511 rs17280643 chr12:86210154 C/T cg02569458 chr12:86230093 RASSF9 -0.44 -5.89 -0.3 9.03e-9 Major depressive disorder; LIHC cis rs9733 0.596 rs7529998 chr1:150662531 C/T cg17724175 chr1:150552817 MCL1 0.48 9.72 0.47 7.13e-20 Tonsillectomy; LIHC cis rs7833790 0.654 rs6415652 chr8:82702257 G/A cg17211192 chr8:82754475 SNX16 -0.53 -9.32 -0.45 1.45e-18 Diastolic blood pressure; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg20607798 chr8:58055168 NA 0.64 7.95 0.39 2.75e-14 Developmental language disorder (linguistic errors); LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg09367891 chr1:107599246 PRMT6 -0.72 -11.87 -0.54 1.92e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg04944784 chr2:26401820 FAM59B 0.72 8.81 0.43 6.49e-17 Gut microbiome composition (summer); LIHC cis rs2404602 0.631 rs9646213 chr15:76807672 G/C cg23625390 chr15:77176239 SCAPER 0.36 5.95 0.31 6.75e-9 Blood metabolite levels; LIHC cis rs9296092 0.517 rs55683509 chr6:33471077 A/G cg13560919 chr6:33536144 NA -0.38 -6.06 -0.31 3.58e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs1008375 1.000 rs10805358 chr4:17652450 A/C cg02297831 chr4:17616191 MED28 0.48 7.48 0.38 6.23e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.5 -0.38 5.41e-13 Initial pursuit acceleration; LIHC cis rs3806843 0.933 rs10069930 chr5:140163328 T/A cg26395211 chr5:140044315 WDR55 -0.43 -6.32 -0.32 8.19e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg06873352 chr17:61820015 STRADA 0.58 8.87 0.43 4.25e-17 Height; LIHC cis rs13191362 0.935 rs66507030 chr6:162953825 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.7 6.05 0.31 3.91e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC trans rs6489882 0.867 rs7958379 chr12:113363284 A/G cg10175203 chr3:128143634 NA 0.38 6.1 0.31 2.83e-9 Chronic lymphocytic leukemia; LIHC cis rs926392 1.000 rs926392 chr20:37690464 A/G cg16355469 chr20:37678765 NA 0.37 5.95 0.31 6.53e-9 Dialysis-related mortality; LIHC cis rs12602486 1.000 rs60684277 chr17:42281307 G/A cg13607699 chr17:42295918 UBTF -0.78 -6.63 -0.34 1.29e-10 Glycated hemoglobin levels; LIHC cis rs10876993 0.928 rs2928053 chr12:58063475 T/C cg18357645 chr12:58087776 OS9 0.51 8.34 0.41 1.8e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs8044995 0.517 rs2863973 chr16:68409435 A/C cg05110241 chr16:68378359 PRMT7 -0.66 -7.52 -0.38 5.01e-13 Schizophrenia; LIHC cis rs11711311 1.000 rs12632983 chr3:113481913 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.28 -0.37 2.29e-12 IgG glycosylation; LIHC cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg24549020 chr5:56110836 MAP3K1 0.47 6.03 0.31 4.21e-9 Initial pursuit acceleration; LIHC cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg26116260 chr4:7069785 GRPEL1 1.01 19.13 0.72 5.34e-56 Monocyte percentage of white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18827097 chr2:3522506 ADI1 0.5 7.41 0.37 1.03e-12 Pancreatic cancer; LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg16060761 chr17:80687452 NA -0.48 -7.19 -0.36 4.03e-12 Glycated hemoglobin levels; LIHC cis rs1355223 0.902 rs35032224 chr11:34698154 T/C cg11058730 chr11:34937778 PDHX;APIP -0.43 -6.03 -0.31 4.14e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg20887711 chr4:1340912 KIAA1530 -0.48 -7.45 -0.37 7.76e-13 Obesity-related traits; LIHC cis rs4930561 1.000 rs4930561 chr11:67931761 C/T cg04465784 chr11:67976953 SUV420H1 -0.26 -5.94 -0.31 7.14e-9 Breast cancer in childhood cancer survivors;IgG glycosylation; LIHC cis rs8038465 0.622 rs17185525 chr15:73885539 T/C cg15420318 chr15:73925796 NPTN 0.5 7.28 0.37 2.31e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11827097 chr2:231280903 SP100 0.44 6.13 0.31 2.46e-9 Pancreatic cancer; LIHC cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg24209194 chr3:40518798 ZNF619 -0.51 -7.52 -0.38 4.77e-13 Renal cell carcinoma; LIHC cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.93 8.33 0.41 2.03e-15 Platelet count; LIHC cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg10802521 chr3:52805072 NEK4 -0.34 -5.72 -0.3 2.31e-8 Bipolar disorder; LIHC cis rs858239 0.636 rs28706766 chr7:23169834 T/A cg23682824 chr7:23144976 KLHL7 0.4 6.0 0.31 4.94e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs748404 0.697 rs498227 chr15:43573052 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 6.9 0.35 2.58e-11 Lung cancer; LIHC cis rs2032447 0.839 rs6901039 chr6:26000885 A/C cg03264133 chr6:25882463 NA -0.57 -7.38 -0.37 1.2e-12 Intelligence (multi-trait analysis); LIHC cis rs8044868 0.530 rs4788464 chr16:72223899 T/C cg16558253 chr16:72132732 DHX38 -0.38 -6.36 -0.33 6.44e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs1152591 0.543 rs1152592 chr14:64676098 A/G cg21174375 chr14:64681225 SYNE2 0.38 6.1 0.31 2.86e-9 Atrial fibrillation; LIHC cis rs11583043 1.000 rs11583043 chr1:101466054 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.96 0.44 2.09e-17 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs911119 0.954 rs35966482 chr20:23620716 G/T cg16589663 chr20:23618590 CST3 0.76 7.97 0.4 2.44e-14 Chronic kidney disease; LIHC cis rs11871801 0.517 rs668799 chr17:40716235 C/T cg14558262 chr17:40713999 COASY 0.63 9.7 0.46 8.39e-20 Crohn's disease; LIHC cis rs637571 0.522 rs12797319 chr11:65735672 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.82 0.43 5.98e-17 Eosinophil percentage of white cells; LIHC cis rs9372253 1.000 rs2235989 chr6:110714584 A/T cg19196401 chr6:110721138 DDO -0.32 -6.48 -0.33 3.13e-10 Platelet distribution width; LIHC cis rs34172651 0.917 rs6497760 chr16:24806535 G/A cg04756594 chr16:24857601 SLC5A11 0.48 7.46 0.37 7.15e-13 Intelligence (multi-trait analysis); LIHC cis rs1062177 1.000 rs12653926 chr5:151250248 C/A cg00977110 chr5:151150581 G3BP1 0.51 6.34 0.32 7.45e-10 Preschool internalizing problems; LIHC trans rs7615952 0.673 rs9841194 chr3:125635739 C/T cg07211511 chr3:129823064 LOC729375 -0.81 -8.38 -0.41 1.35e-15 Blood pressure (smoking interaction); LIHC cis rs9457247 1.000 rs448060 chr6:167382622 A/G cg12798992 chr6:167411361 FGFR1OP 0.59 9.73 0.47 6.7e-20 Crohn's disease; LIHC cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg05890377 chr2:74357713 NA 0.64 12.93 0.57 2.11e-31 Gestational age at birth (maternal effect); LIHC cis rs10423674 0.526 rs11668545 chr19:18829529 C/T cg16673477 chr19:18812017 CRTC1 -0.41 -6.64 -0.34 1.26e-10 Menarche (age at onset); LIHC cis rs919433 0.679 rs10497806 chr2:198508951 G/A cg10820045 chr2:198174542 NA 0.48 7.49 0.38 5.73e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11190604 1.000 rs17746014 chr10:102315354 T/C cg07080220 chr10:102295463 HIF1AN 0.52 7.08 0.36 8.02e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2439831 0.867 rs2899082 chr15:43656043 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.31 0.52 2.11e-25 Lung cancer in ever smokers; LIHC cis rs7772486 0.846 rs7755440 chr6:146375906 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -6.01 -0.31 4.69e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.641 rs9390370 chr6:146357569 C/T cg05347473 chr6:146136440 FBXO30 0.45 6.9 0.35 2.53e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11190604 1.000 rs3793771 chr10:102222957 C/G cg07080220 chr10:102295463 HIF1AN 0.48 6.73 0.34 6.98e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7312774 0.618 rs7304621 chr12:107325888 C/T cg16260113 chr12:107380972 MTERFD3 0.83 10.83 0.51 1.07e-23 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg06634786 chr22:41940651 POLR3H -0.71 -7.61 -0.38 2.76e-13 Vitiligo; LIHC cis rs7412746 0.658 rs7521719 chr1:150913134 G/A cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs17253792 0.822 rs77599953 chr14:56058905 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.49 -0.42 6.46e-16 Putamen volume; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg08677398 chr8:58056175 NA 0.4 6.05 0.31 3.89e-9 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.67 9.68 0.46 9.89e-20 Lymphocyte counts; LIHC cis rs67478160 0.608 rs34066659 chr14:104263427 A/C cg08213375 chr14:104286397 PPP1R13B 0.65 12.87 0.57 3.42e-31 Schizophrenia; LIHC cis rs11718455 0.653 rs28533958 chr3:43974179 C/A cg08738300 chr3:44038990 NA 0.53 8.95 0.44 2.31e-17 Coronary artery disease; LIHC cis rs78456975 0.527 rs10203194 chr2:1558021 A/G cg01028140 chr2:1542097 TPO -0.42 -6.56 -0.33 2.05e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg18357526 chr6:26021779 HIST1H4A 0.89 12.96 0.57 1.58e-31 Intelligence (multi-trait analysis); LIHC cis rs4407350 1.000 rs5765724 chr22:44921575 G/C cg11695653 chr22:44894386 LDOC1L -0.37 -6.11 -0.31 2.64e-9 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.904 rs1966916 chr17:37425238 T/G cg03013999 chr17:37608204 MED1 0.36 6.03 0.31 4.18e-9 Glomerular filtration rate (creatinine); LIHC cis rs7582720 1.000 rs72936326 chr2:204054141 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs992157 0.835 rs12987219 chr2:219144149 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.12 -0.55 2.19e-28 Colorectal cancer; LIHC trans rs7618501 0.699 rs1317154 chr3:49910084 T/C cg21659725 chr3:3221576 CRBN 0.72 11.26 0.52 3.11e-25 Intelligence (multi-trait analysis); LIHC cis rs7260329 0.507 rs1552222 chr19:41525904 T/A cg10403441 chr19:41533888 NA 0.46 6.12 0.31 2.58e-9 Smoking behavior; LIHC cis rs6429082 0.902 rs704708 chr1:235620134 T/C cg26050004 chr1:235667680 B3GALNT2 0.39 6.11 0.31 2.77e-9 Adiposity; LIHC cis rs12142240 0.698 rs17361915 chr1:46847321 C/T cg00530320 chr1:46809349 NSUN4 0.53 5.78 0.3 1.68e-8 Menopause (age at onset); LIHC cis rs7666738 0.830 rs4292341 chr4:98959724 C/T cg05340658 chr4:99064831 C4orf37 0.55 9.39 0.45 8.39e-19 Colonoscopy-negative controls vs population controls; LIHC cis rs7584330 0.955 rs58643200 chr2:238389855 A/G cg14458575 chr2:238380390 NA 0.37 6.02 0.31 4.39e-9 Prostate cancer; LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg26338869 chr17:61819248 STRADA 0.54 7.17 0.36 4.67e-12 Height; LIHC cis rs17253792 0.822 rs74051609 chr14:56171132 G/A cg01858014 chr14:56050164 KTN1 -0.62 -6.76 -0.34 6.02e-11 Putamen volume; LIHC cis rs7909074 0.691 rs11239274 chr10:45393219 A/C cg04218760 chr10:45406644 TMEM72 0.2 5.74 0.3 2.13e-8 Mean corpuscular volume; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg03874509 chr1:107600012 PRMT6 0.73 11.65 0.53 1.26e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs937213 0.676 rs8042456 chr15:40290476 G/T cg16127683 chr15:40268777 EIF2AK4 -0.44 -6.7 -0.34 8.53e-11 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC trans rs6489882 0.867 rs7316586 chr12:113365828 C/T cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 21.95 0.76 2.86e-67 Prudent dietary pattern; LIHC cis rs727563 0.555 rs5751136 chr22:42075581 T/A cg03806693 chr22:41940476 POLR3H 0.91 10.06 0.48 5.21e-21 Crohn's disease;Inflammatory bowel disease; LIHC cis rs13064411 0.735 rs722392 chr3:113228294 A/G cg18753928 chr3:113234510 CCDC52 -0.43 -6.08 -0.31 3.14e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg16405210 chr4:1374714 KIAA1530 -0.69 -10.45 -0.49 2.24e-22 Longevity; LIHC cis rs7737355 0.947 rs32113 chr5:131049585 G/T cg06307176 chr5:131281290 NA -0.41 -6.01 -0.31 4.66e-9 Life satisfaction; LIHC cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs74417235 0.684 rs7723312 chr5:154053249 A/G cg08893839 chr5:154027129 NA -0.5 -6.86 -0.35 3.3e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs60871478 0.636 rs4719520 chr7:875216 C/G cg05535760 chr7:792225 HEATR2 -0.82 -6.6 -0.34 1.53e-10 Cerebrospinal P-tau181p levels; LIHC cis rs8044995 0.568 rs55675218 chr16:68323647 G/C cg05110241 chr16:68378359 PRMT7 -0.92 -9.38 -0.45 9.61e-19 Schizophrenia; LIHC cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg05535760 chr7:792225 HEATR2 -0.49 -6.74 -0.34 6.85e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs317689 0.718 rs160827 chr12:69770147 G/A cg14784868 chr12:69753453 YEATS4 0.68 10.27 0.49 9.42e-22 Response to diuretic therapy; LIHC cis rs16958440 0.581 rs72907280 chr18:44681130 C/T cg17192377 chr18:44677553 HDHD2 0.71 7.79 0.39 8.32e-14 Sitting height ratio; LIHC cis rs950776 0.518 rs55690619 chr15:78833612 A/G cg22563815 chr15:78856949 CHRNA5 -0.36 -6.74 -0.34 6.81e-11 Sudden cardiac arrest; LIHC cis rs7552404 1.000 rs1498315 chr1:76159225 G/A cg22875332 chr1:76189707 ACADM 0.48 7.1 0.36 7.4e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2832191 1.000 rs2832185 chr21:30483761 C/G cg24692254 chr21:30365293 RNF160 -0.64 -11.32 -0.52 1.86e-25 Dental caries; LIHC trans rs66887589 0.934 rs4834792 chr4:120555696 T/A cg25214090 chr10:38739885 LOC399744 -0.38 -6.2 -0.32 1.65e-9 Diastolic blood pressure; LIHC cis rs4523957 0.614 rs1563966 chr17:2095954 A/G cg16513277 chr17:2031491 SMG6 0.44 7.06 0.36 9.32e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01117833 chr14:94547303 DDX24;IFI27L1 0.37 6.23 0.32 1.37e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6466055 0.720 rs4730080 chr7:105001133 T/C cg04380332 chr7:105027541 SRPK2 -0.37 -6.89 -0.35 2.66e-11 Schizophrenia; LIHC cis rs208520 0.690 rs864314 chr6:66814830 G/A cg07460842 chr6:66804631 NA -1.02 -19.93 -0.73 3.41e-59 Exhaled nitric oxide output; LIHC cis rs2580764 0.517 rs2972070 chr2:55301691 G/A cg09592903 chr2:55203963 RTN4 0.62 11.27 0.52 2.79e-25 Mean platelet volume; LIHC cis rs1982963 0.627 rs61971554 chr14:52491583 A/G cg10843707 chr14:52510701 NID2 0.36 5.84 0.3 1.18e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg16405210 chr4:1374714 KIAA1530 0.41 6.07 0.31 3.46e-9 Obesity-related traits; LIHC cis rs208515 0.525 rs10944868 chr6:66687508 A/G cg07460842 chr6:66804631 NA 0.78 8.98 0.44 1.88e-17 Exhaled nitric oxide levels; LIHC cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg09904177 chr6:26538194 HMGN4 0.57 11.54 0.53 2.97e-26 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.59 -0.56 4.11e-30 Alzheimer's disease; LIHC cis rs10489202 1.000 rs10489202 chr1:167903079 A/C cg24449463 chr1:168025552 DCAF6 0.53 6.77 0.34 5.69e-11 Schizophrenia; LIHC trans rs8113308 0.688 rs7259507 chr19:52445728 A/G cg14959425 chr7:20447707 ITGB8 -0.47 -6.1 -0.31 2.87e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs12079745 0.793 rs12092952 chr1:169389715 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.82 -7.17 -0.36 4.62e-12 QT interval; LIHC cis rs2032447 0.507 rs478349 chr6:25894057 T/C cg18357526 chr6:26021779 HIST1H4A 0.96 11.55 0.53 2.78e-26 Intelligence (multi-trait analysis); LIHC cis rs6450176 0.625 rs16881958 chr5:53288201 C/G ch.5.1024479R chr5:53302184 ARL15 -0.88 -16.31 -0.66 1.22e-44 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2880765 0.566 rs17553790 chr15:86013665 C/T cg10818794 chr15:86012489 AKAP13 0.43 6.49 0.33 3.07e-10 Coronary artery disease; LIHC cis rs225245 0.817 rs1476553 chr17:33994566 C/T cg05299278 chr17:33885742 SLFN14 0.23 6.22 0.32 1.45e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg12463550 chr7:65579703 CRCP 0.69 7.07 0.36 8.94e-12 Diabetic kidney disease; LIHC cis rs10170846 0.893 rs11692810 chr2:223544096 A/C cg25565276 chr2:223520875 FARSB -0.61 -9.09 -0.44 8.15e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs7577696 0.597 rs6756085 chr2:32336522 A/G cg02381751 chr2:32503542 YIPF4 -0.45 -6.36 -0.33 6.44e-10 Inflammatory biomarkers; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.89 0.57 2.96e-31 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs4149468 chr7:65825690 T/C cg05590025 chr7:65112418 INTS4L2 -0.54 -5.91 -0.3 8.45e-9 Diabetic kidney disease; LIHC cis rs6062302 0.522 rs3787112 chr20:62222411 G/A cg16989086 chr20:62203971 PRIC285 0.56 8.07 0.4 1.2e-14 Glioblastoma; LIHC cis rs2806561 0.704 rs636940 chr1:23522967 A/T cg19743168 chr1:23544995 NA 0.38 6.27 0.32 1.07e-9 Height; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.1 0.55 2.65e-28 Height; LIHC cis rs7520050 0.966 rs34102169 chr1:46424864 G/T cg03146154 chr1:46216737 IPP -0.38 -6.29 -0.32 9.94e-10 Red blood cell count;Reticulocyte count; LIHC cis rs72627509 0.904 rs17081935 chr4:57823476 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.59 -8.33 -0.41 1.97e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs11583043 0.874 rs11578366 chr1:101396852 T/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.42 0.41 1.05e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs6424115 1.000 rs2256179 chr1:24132305 A/G cg10978503 chr1:24200527 CNR2 -0.36 -8.44 -0.42 9.08e-16 Immature fraction of reticulocytes; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg04267008 chr7:1944627 MAD1L1 -0.67 -11.13 -0.52 9.51e-25 Autism spectrum disorder or schizophrenia; LIHC cis rs7909074 0.899 rs2026428 chr10:45389452 T/C cg04218760 chr10:45406644 TMEM72 -0.25 -7.83 -0.39 6.11e-14 Mean corpuscular volume; LIHC cis rs11098499 0.954 rs12506546 chr4:120301618 T/C cg09307838 chr4:120376055 NA 0.75 11.44 0.53 7.26e-26 Corneal astigmatism; LIHC cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg21782813 chr7:2030301 MAD1L1 0.5 8.73 0.43 1.17e-16 Bipolar disorder and schizophrenia; LIHC cis rs700651 0.789 rs6715070 chr2:198898265 A/G cg10820045 chr2:198174542 NA -0.43 -6.53 -0.33 2.35e-10 Intracranial aneurysm; LIHC cis rs10197940 0.648 rs7587301 chr2:152347600 A/G cg19508488 chr2:152266495 RIF1 0.47 6.69 0.34 9.13e-11 Lung cancer; LIHC cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.71 -12.56 -0.56 5.15e-30 Prudent dietary pattern; LIHC cis rs12497850 0.805 rs6446198 chr3:49007638 T/A cg06212747 chr3:49208901 KLHDC8B 0.56 7.15 0.36 5.31e-12 Parkinson's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17127132 chr2:85788382 GGCX 0.4 6.14 0.32 2.31e-9 Pancreatic cancer; LIHC cis rs7100689 0.556 rs946893 chr10:82023524 A/G cg01528321 chr10:82214614 TSPAN14 0.76 10.16 0.48 2.22e-21 Post bronchodilator FEV1; LIHC cis rs72653721 0.730 rs56074859 chr6:11044089 C/T cg13562911 chr6:11044106 ELOVL2 0.52 7.45 0.37 7.45e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs12701220 0.696 rs12112029 chr7:1137889 G/A cg04498913 chr7:1135747 C7orf50 0.43 6.9 0.35 2.52e-11 Bronchopulmonary dysplasia; LIHC cis rs992157 0.735 rs13393821 chr2:219076742 C/G cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.51 0.59 1.31e-33 Colorectal cancer; LIHC cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg11644478 chr21:40555479 PSMG1 0.83 10.86 0.51 8.58e-24 Cognitive function; LIHC cis rs244731 0.959 rs4976677 chr5:176629546 G/A cg17509989 chr5:176798049 RGS14 -0.68 -6.42 -0.33 4.58e-10 Urate levels in lean individuals; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03390569 chr2:54013802 LOC100302652;ASB3;ERLEC1 -0.49 -6.27 -0.32 1.08e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6815814 0.731 rs11734342 chr4:38773109 A/G cg06935464 chr4:38784597 TLR10 0.37 5.93 0.31 7.47e-9 Breast cancer; LIHC cis rs62034325 0.697 rs710410 chr16:28603342 A/G cg16576597 chr16:28551801 NUPR1 0.47 6.99 0.35 1.43e-11 Body mass index; LIHC cis rs16944613 0.510 rs10520692 chr15:91154471 A/G cg26821196 chr15:91095069 CRTC3 0.31 5.91 0.3 8.06e-9 Colorectal cancer; LIHC cis rs1801251 1.000 rs7578299 chr2:233573469 G/T cg25237894 chr2:233734115 C2orf82 0.57 11.02 0.51 2.3e-24 Coronary artery disease; LIHC cis rs1691799 0.899 rs1168303 chr12:66738586 A/G cg16791601 chr12:66731901 HELB -0.57 -13.85 -0.6 6.11e-35 White blood cell count (basophil); LIHC cis rs3020736 0.500 rs6002603 chr22:42492362 C/G cg05082376 chr22:42548792 NA 0.39 5.71 0.3 2.41e-8 Autism spectrum disorder or schizophrenia; LIHC trans rs792448 0.743 rs351378 chr1:212425196 T/C cg20223728 chr6:6006398 NRN1 0.35 6.2 0.32 1.65e-9 White blood cell count (basophil); LIHC cis rs9583531 0.574 rs61971615 chr13:111353111 C/T cg24331049 chr13:111365604 ING1 -0.76 -12.77 -0.57 8.35e-31 Coronary artery disease; LIHC trans rs208520 1.000 rs12195505 chr6:66986279 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.07 0.36 8.67e-12 Exhaled nitric oxide output; LIHC cis rs8005677 1.000 rs1956880 chr14:23394007 A/G cg07971674 chr14:23388846 RBM23 -0.41 -5.97 -0.31 6.01e-9 Cognitive ability (multi-trait analysis); LIHC cis rs270601 0.739 rs1979981 chr5:131601720 G/A cg24060327 chr5:131705240 SLC22A5 -0.53 -6.94 -0.35 1.96e-11 Acylcarnitine levels; LIHC cis rs61990749 0.597 rs1477260 chr14:78256818 G/C cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.0 0.48 8.3e-21 Fibroblast growth factor basic levels; LIHC cis rs611744 1.000 rs611744 chr8:109228008 A/G cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs9381040 0.655 rs2268188 chr6:41042590 T/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.37 -5.86 -0.3 1.08e-8 Alzheimer's disease (late onset); LIHC cis rs11690935 0.655 rs12052995 chr2:172537212 A/G cg13550731 chr2:172543902 DYNC1I2 0.64 11.71 0.53 7.6e-27 Schizophrenia; LIHC cis rs1538970 0.924 rs12097497 chr1:45880669 C/T cg24296786 chr1:45957014 TESK2 -0.5 -7.35 -0.37 1.51e-12 Platelet count; LIHC cis rs2191566 0.664 rs62115482 chr19:44554083 C/A cg20607764 chr19:44506953 ZNF230 -0.37 -6.14 -0.32 2.24e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs9814567 0.929 rs1863911 chr3:134205231 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.09 -0.55 2.81e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6912958 0.712 rs6930600 chr6:88349787 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.91 -0.39 3.48e-14 Monocyte percentage of white cells; LIHC cis rs208520 0.955 rs28684412 chr6:66979430 A/C cg07460842 chr6:66804631 NA 0.67 7.3 0.37 2.1e-12 Exhaled nitric oxide output; LIHC cis rs6442522 1.000 rs13075694 chr3:15450400 C/T cg16303742 chr3:15540471 COLQ 0.41 6.95 0.35 1.91e-11 Uric acid levels; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg02290350 chr8:58132656 NA 0.5 10.21 0.48 1.49e-21 Developmental language disorder (linguistic errors); LIHC cis rs9443189 0.570 rs72884926 chr6:76266208 T/C cg01950844 chr6:76311363 SENP6 0.9 11.02 0.51 2.34e-24 Prostate cancer; LIHC cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg03806693 chr22:41940476 POLR3H 1.09 13.07 0.58 6.34e-32 Vitiligo; LIHC cis rs908922 0.651 rs6671924 chr1:152485830 T/C cg20991723 chr1:152506922 NA 0.55 9.44 0.45 6.15e-19 Hair morphology; LIHC cis rs929354 0.713 rs6946947 chr7:156948787 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs3099143 0.901 rs76036665 chr15:77232720 A/G cg21673338 chr15:77095150 SCAPER -0.54 -7.34 -0.37 1.57e-12 Recalcitrant atopic dermatitis; LIHC cis rs1552244 0.572 rs59132826 chr3:10169725 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs6540556 0.723 rs1415542 chr1:209902110 T/C cg05527609 chr1:210001259 C1orf107 -0.58 -7.83 -0.39 6.22e-14 Red blood cell count; LIHC cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg21724239 chr8:58056113 NA 0.49 6.36 0.33 6.38e-10 Developmental language disorder (linguistic errors); LIHC cis rs9308433 0.529 rs4655244 chr1:214497580 A/G cg06198575 chr1:214491504 SMYD2 0.56 5.92 0.3 7.86e-9 IgG glycosylation; LIHC trans rs877282 1.000 rs11253367 chr10:773389 G/A cg22713356 chr15:30763199 NA 1.24 11.03 0.51 2.16e-24 Uric acid levels; LIHC cis rs10911232 0.507 rs4652762 chr1:182993960 T/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg02290350 chr8:58132656 NA 0.49 10.45 0.49 2.26e-22 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.42 -0.41 1.04e-15 Lymphocyte counts; LIHC cis rs11077998 0.967 rs4789790 chr17:80510789 G/A cg10255544 chr17:80519551 FOXK2 0.49 8.97 0.44 1.96e-17 Reticulocyte fraction of red cells; LIHC cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg11645453 chr3:52864694 ITIH4 0.21 5.82 0.3 1.38e-8 Bipolar disorder; LIHC cis rs79149102 0.579 rs12593542 chr15:75282147 C/G cg09165964 chr15:75287851 SCAMP5 -0.51 -6.93 -0.35 2.06e-11 Lung cancer; LIHC cis rs1552244 0.554 rs4488814 chr3:10002400 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 0.5 7.95 0.39 2.75e-14 Alzheimer's disease; LIHC cis rs6546550 0.867 rs1048266 chr2:70132676 A/G cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC cis rs1568889 0.838 rs10835304 chr11:28296529 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.23 0.61 2.02e-36 Bipolar disorder; LIHC cis rs7551222 0.721 rs4951080 chr1:204533284 A/G cg20240347 chr1:204465584 NA -0.34 -7.13 -0.36 5.89e-12 Schizophrenia; LIHC cis rs8038465 0.615 rs6495074 chr15:73959013 A/G cg15420318 chr15:73925796 NPTN 0.44 6.75 0.34 6.24e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7312933 0.703 rs2406567 chr12:42551479 G/C cg17420585 chr12:42539391 GXYLT1 -0.37 -5.98 -0.31 5.63e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs4906332 0.868 rs4900578 chr14:103926010 A/T cg17675199 chr6:35436792 RPL10A 0.34 6.63 0.34 1.32e-10 Coronary artery disease; LIHC cis rs12079745 0.793 rs78967023 chr1:169419543 C/G cg09363564 chr1:169337483 NME7;BLZF1 -0.72 -6.62 -0.34 1.37e-10 QT interval; LIHC cis rs7309 0.935 rs1921309 chr2:162048975 T/A cg13854012 chr2:162103682 NA -0.35 -6.52 -0.33 2.47e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs7772486 0.790 rs6923545 chr6:146244743 A/G cg05347473 chr6:146136440 FBXO30 -0.39 -6.13 -0.31 2.41e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg13409248 chr3:40428643 ENTPD3 -0.5 -8.4 -0.41 1.23e-15 Renal cell carcinoma; LIHC cis rs3018712 0.532 rs55761963 chr11:68402629 G/T cg20283391 chr11:68216788 NA -0.5 -5.99 -0.31 5.23e-9 Total body bone mineral density; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg06820907 chr2:242122206 PPP1R7 0.42 6.62 0.34 1.37e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs12701220 0.504 rs12702092 chr7:1145868 G/A cg16145915 chr7:1198662 ZFAND2A -0.31 -5.85 -0.3 1.14e-8 Bronchopulmonary dysplasia; LIHC cis rs1816752 0.875 rs1050110 chr13:25009485 C/G cg22771759 chr13:24902376 NA 0.32 6.6 0.34 1.54e-10 Obesity-related traits; LIHC cis rs4934494 0.727 rs2418929 chr10:91501477 C/G cg19698084 chr10:91461284 KIF20B -0.45 -6.02 -0.31 4.44e-9 Red blood cell count; LIHC trans rs11098499 0.644 rs10012252 chr4:120559139 T/C cg25214090 chr10:38739885 LOC399744 0.5 8.04 0.4 1.51e-14 Corneal astigmatism; LIHC cis rs13191362 1.000 rs34655790 chr6:163202739 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.81 6.71 0.34 8.15e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 9.19 0.45 3.83e-18 Platelet count; LIHC cis rs2637266 0.783 rs7900420 chr10:78476543 T/C cg18941641 chr10:78392320 NA 0.27 5.81 0.3 1.45e-8 Pulmonary function; LIHC trans rs4843747 0.671 rs8053377 chr16:88106465 A/G cg09572067 chr16:29127029 RRN3P2 0.5 7.88 0.39 4.55e-14 Menopause (age at onset); LIHC cis rs7534824 0.625 rs17525507 chr1:101430504 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 7.0 0.35 1.34e-11 Refractive astigmatism; LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg07133347 chr1:107600762 PRMT6 0.46 6.83 0.35 3.87e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2838344 0.776 rs2298561 chr21:45085234 A/G cg04455712 chr21:45112962 RRP1B 0.51 8.57 0.42 3.55e-16 Coronary artery disease; LIHC cis rs2073300 0.609 rs2277765 chr20:23425163 C/T cg16736954 chr20:23401023 NAPB 0.72 8.44 0.42 9.01e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17854409 1.000 rs66634465 chr20:61482306 C/T cg05147244 chr20:61493195 TCFL5 1.21 11.07 0.51 1.47e-24 Obesity-related traits; LIHC trans rs2243480 0.901 rs2949697 chr7:65464236 A/G cg10756647 chr7:56101905 PSPH 1.11 13.6 0.59 5.63e-34 Diabetic kidney disease; LIHC cis rs7927771 0.524 rs10838775 chr11:47856382 C/G cg20307385 chr11:47447363 PSMC3 0.72 10.82 0.5 1.19e-23 Subjective well-being; LIHC cis rs6449957 0.607 rs251394 chr5:67512000 C/G cg23036683 chr5:67512108 NA 0.53 7.75 0.39 1.05e-13 Cleft lip with or without cleft palate; LIHC cis rs1862618 0.613 rs252889 chr5:56227069 C/A cg24531977 chr5:56204891 C5orf35 -0.54 -7.83 -0.39 6.27e-14 Initial pursuit acceleration; LIHC cis rs6088590 0.523 rs6059913 chr20:33143288 G/A cg08999081 chr20:33150536 PIGU 0.68 13.8 0.6 9.85e-35 Coronary artery disease; LIHC cis rs7296418 0.961 rs61955196 chr12:123451018 G/C cg05973401 chr12:123451056 ABCB9 0.46 6.97 0.35 1.67e-11 Platelet count; LIHC cis rs9309473 1.000 rs6710438 chr2:73820108 C/G cg20560298 chr2:73613845 ALMS1 0.51 6.12 0.31 2.57e-9 Metabolite levels; LIHC cis rs7674212 0.540 rs2711897 chr4:104023567 C/T cg16532752 chr4:104119610 CENPE -0.43 -6.86 -0.35 3.31e-11 Type 2 diabetes; LIHC cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg00149659 chr3:10157352 C3orf10 -0.69 -7.3 -0.37 2.05e-12 Alzheimer's disease; LIHC cis rs7412746 0.634 rs3754212 chr1:150738200 A/G cg17724175 chr1:150552817 MCL1 0.48 9.3 0.45 1.65e-18 Melanoma; LIHC cis rs10911251 0.546 rs10911260 chr1:183106230 A/C ch.1.3577855R chr1:183094577 LAMC1 -0.59 -10.46 -0.49 2.06e-22 Colorectal cancer; LIHC cis rs2404602 0.647 rs8025991 chr15:77155268 C/T cg03037974 chr15:76606532 NA -0.59 -10.09 -0.48 4.02e-21 Blood metabolite levels; LIHC trans rs7657257 1.000 rs11931532 chr4:15725766 A/G cg17675199 chr6:35436792 RPL10A -0.39 -6.26 -0.32 1.12e-9 Blood protein levels; LIHC cis rs4407350 0.756 rs135622 chr22:44890658 T/C cg11695653 chr22:44894386 LDOC1L -0.38 -6.45 -0.33 3.88e-10 Intelligence (multi-trait analysis); LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg03255221 chr20:57617810 SLMO2 0.45 6.03 0.31 4.15e-9 Gut microbiome composition (summer); LIHC cis rs6952808 0.929 rs11761270 chr7:1923695 C/T cg21782813 chr7:2030301 MAD1L1 0.45 7.48 0.37 6.39e-13 Bipolar disorder and schizophrenia; LIHC cis rs6933660 0.800 rs13201167 chr6:151773504 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.51 7.34 0.37 1.6e-12 Menarche (age at onset); LIHC cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg02290350 chr8:58132656 NA 0.4 8.44 0.42 9.38e-16 Developmental language disorder (linguistic errors); LIHC cis rs62458065 0.513 rs10265319 chr7:32571564 A/C cg06627557 chr7:32535165 LSM5;AVL9 -0.72 -7.07 -0.36 8.67e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs12478296 1.000 rs7603984 chr2:243047294 A/G cg06360820 chr2:242988706 NA -0.95 -12.4 -0.56 2.1e-29 Obesity-related traits; LIHC cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.37 0.45 9.93e-19 Bipolar disorder; LIHC cis rs892961 0.932 rs7208336 chr17:75412932 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs7264396 1.000 rs224436 chr20:34154124 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.94 -0.35 2.02e-11 Total cholesterol levels; LIHC cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.22 -0.36 3.29e-12 Bipolar disorder; LIHC cis rs11955398 0.716 rs3857236 chr5:59909529 G/A cg02684056 chr5:59996105 DEPDC1B 0.41 6.09 0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs365132 0.967 rs58279426 chr5:176448139 T/C cg16309518 chr5:176445507 NA -0.58 -11.45 -0.53 6.54e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg04267008 chr7:1944627 MAD1L1 -0.61 -9.8 -0.47 3.77e-20 Bipolar disorder and schizophrenia; LIHC cis rs67311347 0.822 rs11709089 chr3:40351484 C/T cg09455208 chr3:40491958 NA 0.33 6.29 0.32 9.45e-10 Renal cell carcinoma; LIHC cis rs7552404 1.000 rs11161515 chr1:76212559 C/T cg10523679 chr1:76189770 ACADM 0.63 8.59 0.42 3.11e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6121246 0.909 rs1994249 chr20:30287593 C/T cg13852791 chr20:30311386 BCL2L1 0.94 9.63 0.46 1.39e-19 Mean corpuscular hemoglobin; LIHC cis rs3008870 1.000 rs3008858 chr1:67390416 G/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.45 0.66 3.47e-45 Lymphocyte percentage of white cells; LIHC cis rs921968 0.541 rs4674308 chr2:219310483 A/C cg02176678 chr2:219576539 TTLL4 0.57 7.89 0.39 4.22e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs11098499 0.754 rs714899 chr4:120243035 G/A cg09307838 chr4:120376055 NA 0.71 11.05 0.51 1.77e-24 Corneal astigmatism; LIHC cis rs72781680 0.898 rs72782113 chr2:24024952 G/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs3020736 0.500 rs2413669 chr22:42507748 A/C cg15557168 chr22:42548783 NA 0.43 6.78 0.34 5.3e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs7786877 0.680 rs12532878 chr7:100212254 G/A cg00334542 chr7:100209784 MOSPD3 -0.72 -7.41 -0.37 1.01e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs916888 0.821 rs199507 chr17:44858855 A/G cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2599510 0.783 rs2710626 chr2:32758754 G/C cg02381751 chr2:32503542 YIPF4 0.48 6.66 0.34 1.07e-10 Interleukin-18 levels; LIHC cis rs600806 0.778 rs891380 chr1:110003286 T/G cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.33 -0.32 7.62e-10 Intelligence (multi-trait analysis); LIHC cis rs17152411 1.000 rs7914110 chr10:126599886 C/G cg07906193 chr10:126599966 NA 0.49 7.4 0.37 1.05e-12 Height; LIHC cis rs2197308 0.765 rs7295711 chr12:37903631 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs75064307 0.834 rs7636575 chr3:108115862 C/T cg03329597 chr3:108125523 MYH15 -0.49 -6.58 -0.34 1.79e-10 Intelligence (multi-trait analysis); LIHC cis rs2710642 0.611 rs1534419 chr2:62883936 C/A cg17519650 chr2:63277830 OTX1 0.52 7.51 0.38 5.26e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs2180341 1.000 rs9385419 chr6:127597591 A/G cg27446573 chr6:127587934 RNF146 1.0 15.32 0.64 1.06e-40 Breast cancer; LIHC cis rs763121 0.853 rs6001191 chr22:39074452 T/C cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs11864453 0.826 rs2240243 chr16:72137561 A/G cg16558253 chr16:72132732 DHX38 0.48 7.47 0.37 6.65e-13 Fibrinogen levels; LIHC cis rs72781680 0.898 rs72782137 chr2:24047805 C/T cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs9326248 0.953 rs488962 chr11:117072525 C/T cg10130564 chr11:117069849 TAGLN -0.37 -6.21 -0.32 1.51e-9 Blood protein levels; LIHC cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg23758822 chr17:41437982 NA 0.94 17.94 0.7 3.44e-51 Menopause (age at onset); LIHC cis rs10426930 0.763 rs7257002 chr19:5043527 G/T cg18473234 chr19:5097819 KDM4B 0.54 6.79 0.34 4.86e-11 Monocyte percentage of white cells; LIHC trans rs4718428 0.705 rs4718424 chr7:66376095 G/A cg10756647 chr7:56101905 PSPH 0.64 8.81 0.43 6.36e-17 Corneal structure; LIHC cis rs6782228 0.527 rs7426806 chr3:128412930 G/A cg16766828 chr3:128327626 NA -0.37 -5.77 -0.3 1.74e-8 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs2455799 0.613 rs2345736 chr3:15824860 T/G cg12698662 chr3:15914712 MIR563 -0.39 -7.32 -0.37 1.74e-12 Mean platelet volume; LIHC cis rs4689592 0.503 rs56099074 chr4:7071259 A/G cg19539972 chr4:7069911 GRPEL1 -0.73 -10.0 -0.48 7.94e-21 Monocyte percentage of white cells; LIHC cis rs738322 0.934 rs133016 chr22:38572582 C/T cg25457927 chr22:38595422 NA -0.27 -6.61 -0.34 1.51e-10 Cutaneous nevi; LIHC trans rs71658797 0.536 rs12034334 chr1:77954397 G/C cg04606550 chr5:14226569 TRIO 0.41 6.25 0.32 1.19e-9 Lung cancer in ever smokers;Lung cancer;Lung adenocarcinoma; LIHC cis rs9658691 0.607 rs9658788 chr10:90776486 T/C cg03111039 chr10:90751583 FAS;ACTA2 -0.86 -6.53 -0.33 2.43e-10 Mosquito bite size; LIHC cis rs12950390 0.814 rs4794099 chr17:45838358 T/C cg03474202 chr17:45855739 NA -0.36 -6.08 -0.31 3.12e-9 IgG glycosylation; LIHC cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg23982607 chr1:1823379 GNB1 -0.72 -14.47 -0.62 2.26e-37 Body mass index; LIHC trans rs4146653 0.671 rs4639834 chr10:4768818 C/T cg25345178 chr8:72459908 NA -0.32 -6.12 -0.31 2.51e-9 Major depressive disorder; LIHC cis rs3793683 0.825 rs3793674 chr10:134555773 C/T cg27297192 chr10:134578999 INPP5A -0.52 -8.26 -0.41 3.33e-15 Migraine; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.19 0.55 1.25e-28 Height; LIHC cis rs611744 0.967 rs641820 chr8:109190717 T/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs6964587 0.934 rs1544377 chr7:91687351 A/G cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs2832191 0.671 rs68101501 chr21:30513229 G/T cg24692254 chr21:30365293 RNF160 -0.43 -6.68 -0.34 9.8e-11 Dental caries; LIHC cis rs10197940 0.662 rs10175134 chr2:152299355 G/A cg19508488 chr2:152266495 RIF1 0.6 8.3 0.41 2.48e-15 Lung cancer; LIHC cis rs11583043 1.000 rs6682873 chr1:101470906 C/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.58 7.83 0.39 6.12e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2153535 0.541 rs6908504 chr6:8456778 A/G cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg23283495 chr1:209979779 IRF6 0.41 6.69 0.34 9.19e-11 Cleft lip with or without cleft palate; LIHC cis rs763121 0.853 rs6519124 chr22:39045099 T/C cg14440974 chr22:39074834 NA -0.35 -5.8 -0.3 1.51e-8 Menopause (age at onset); LIHC cis rs9640161 0.871 rs56156367 chr7:150047201 A/T cg17279839 chr7:150038598 RARRES2 0.58 11.84 0.54 2.36e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs4304924 0.500 rs2281856 chr13:79207644 C/T cg01819759 chr13:79234251 RNF219 -0.46 -6.16 -0.32 2.07e-9 Large artery stroke; LIHC cis rs637571 0.522 rs538954 chr11:65756808 A/G cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.98 0.31 5.59e-9 Eosinophil percentage of white cells; LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg00280220 chr17:61926910 NA 0.43 6.87 0.35 3.04e-11 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00767560 chr19:19887256 LOC284440 0.5 7.91 0.39 3.53e-14 Cognitive function; LIHC cis rs921968 0.541 rs12617603 chr2:219369288 A/G cg02985541 chr2:219472218 PLCD4 -0.42 -6.83 -0.35 3.99e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs503341 0.756 rs480874 chr11:63591965 A/T cg04362095 chr11:63592001 C11orf84 -0.68 -13.73 -0.6 1.85e-34 Pulse pressure; LIHC cis rs929354 0.713 rs6946660 chr7:156948648 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs929354 0.742 rs2107863 chr7:156963731 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs7208859 0.673 rs9911989 chr17:29237702 A/C cg14067834 chr17:29058358 SUZ12P -0.6 -5.86 -0.3 1.11e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4819052 0.851 rs4819043 chr21:46660078 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.52 0.53 3.51e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.32 -5.82 -0.3 1.33e-8 Calcium levels; LIHC cis rs2404602 0.967 rs12148805 chr15:76800659 G/A cg23625390 chr15:77176239 SCAPER 0.4 6.75 0.34 6.2e-11 Blood metabolite levels; LIHC cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.01 -0.35 1.26e-11 Bipolar disorder; LIHC cis rs9303401 0.659 rs7224276 chr17:56897827 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.32 0.58 6.47e-33 Cognitive test performance; LIHC cis rs9486719 0.843 rs2499789 chr6:96844510 T/C cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs12791968 0.917 rs11038238 chr11:45002010 A/G cg11846598 chr11:44996168 LOC221122 -0.45 -8.0 -0.4 1.9e-14 Inhibitory control; LIHC cis rs2274273 0.870 rs11851169 chr14:55815932 G/A cg01864836 chr14:55583639 NA -0.37 -6.59 -0.34 1.66e-10 Protein biomarker; LIHC cis rs918629 0.716 rs6881355 chr5:95274795 C/T cg10483112 chr5:95245456 ELL2 -0.35 -6.02 -0.31 4.47e-9 IgG glycosylation; LIHC cis rs477895 0.713 rs12575642 chr11:63979643 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 9.53 0.46 3.02e-19 Mean platelet volume; LIHC cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg09455208 chr3:40491958 NA 0.37 7.2 0.36 3.89e-12 Renal cell carcinoma; LIHC cis rs507080 0.883 rs12798453 chr11:118561410 T/G cg04173919 chr11:118528438 PHLDB1 0.35 6.58 0.34 1.78e-10 Serum metabolite levels; LIHC cis rs7296418 0.961 rs11613937 chr12:123520071 C/T cg00376283 chr12:123451042 ABCB9 0.75 13.46 0.59 1.94e-33 Platelet count; LIHC cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg27170947 chr2:26402098 FAM59B 0.67 8.4 0.41 1.18e-15 Gut microbiome composition (summer); LIHC cis rs9790314 0.663 rs9811594 chr3:160745935 A/G cg03342759 chr3:160939853 NMD3 -0.57 -7.87 -0.39 4.77e-14 Morning vs. evening chronotype; LIHC cis rs4843747 0.671 rs13334603 chr16:88116016 T/C cg06050784 chr16:88016603 BANP 0.35 6.33 0.32 7.66e-10 Menopause (age at onset); LIHC trans rs7219021 1.000 rs11657371 chr17:46843873 T/C cg14968300 chr8:23585186 NA -0.35 -6.44 -0.33 3.97e-10 Schizophrenia or bipolar disorder; LIHC cis rs7617773 0.925 rs34513961 chr3:48173653 T/C cg11946769 chr3:48343235 NME6 0.77 9.18 0.44 4.23e-18 Coronary artery disease; LIHC trans rs561341 0.843 rs879945 chr17:30242796 G/A cg20587970 chr11:113659929 NA -0.58 -7.1 -0.36 7.31e-12 Hip circumference adjusted for BMI; LIHC cis rs7903847 0.642 rs11189192 chr10:99149403 G/A cg08345082 chr10:99160200 RRP12 -0.39 -6.43 -0.33 4.33e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7617773 0.817 rs936426 chr3:48215253 C/T cg11946769 chr3:48343235 NME6 0.84 11.0 0.51 2.62e-24 Coronary artery disease; LIHC cis rs9309473 0.950 rs6546860 chr2:73844249 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.84 -0.35 3.61e-11 Metabolite levels; LIHC cis rs11122272 0.705 rs2572260 chr1:231486189 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.06 -0.51 1.58e-24 Hemoglobin concentration; LIHC cis rs611744 0.934 rs604698 chr8:109238721 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs17756712 0.527 rs1193742 chr6:635629 T/C cg14374089 chr6:596013 EXOC2 0.42 5.88 0.3 9.56e-9 Vertical cup-disc ratio; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg00958676 chr8:9911641 MSRA 0.54 6.23 0.32 1.36e-9 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs11098499 0.618 rs28491261 chr4:120294900 C/A cg09307838 chr4:120376055 NA 0.77 11.49 0.53 4.54e-26 Corneal astigmatism; LIHC cis rs208520 0.690 rs12202805 chr6:66703903 A/G cg07460842 chr6:66804631 NA -0.73 -8.47 -0.42 7.54e-16 Exhaled nitric oxide output; LIHC cis rs10861342 1.000 rs73395802 chr12:105588718 T/C cg23923672 chr12:105501055 KIAA1033 0.64 7.58 0.38 3.22e-13 IgG glycosylation; LIHC cis rs10193935 1.000 rs10190326 chr2:42388262 A/C cg27598129 chr2:42591480 NA 0.74 11.55 0.53 2.81e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs10792665 0.649 rs4619175 chr11:82741029 G/A cg24227371 chr11:82718527 RAB30 -0.38 -9.25 -0.45 2.49e-18 Obesity-related traits; LIHC cis rs2153535 0.563 rs1737585 chr6:8536594 A/G cg23788917 chr6:8435910 SLC35B3 -0.61 -8.61 -0.42 2.66e-16 Motion sickness; LIHC cis rs921968 0.510 rs591573 chr2:219478193 C/T cg02176678 chr2:219576539 TTLL4 0.52 7.23 0.36 3.2e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs2153535 0.601 rs7775274 chr6:8530303 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.72 0.54 6.76e-27 Motion sickness; LIHC cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.59 0.38 3.12e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4474465 0.850 rs10899551 chr11:78256998 A/C cg27205649 chr11:78285834 NARS2 -0.38 -5.89 -0.3 9.24e-9 Alzheimer's disease (survival time); LIHC cis rs797680 0.856 rs6703310 chr1:93788740 A/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.06 -0.31 3.6e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs644799 0.562 rs654345 chr11:95581865 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.67 10.99 0.51 3.01e-24 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs5769765 0.955 rs2295406 chr22:50260169 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs1801251 0.963 rs13021246 chr2:233623111 T/C cg25237894 chr2:233734115 C2orf82 0.58 11.21 0.52 4.87e-25 Coronary artery disease; LIHC cis rs8078723 0.714 rs2241244 chr17:38153554 G/C cg17344932 chr17:38183730 MED24;SNORD124 0.69 11.81 0.54 3.16e-27 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7903847 0.642 rs7896100 chr10:99156994 C/T cg20016023 chr10:99160130 RRP12 -0.43 -6.69 -0.34 8.95e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs12188164 0.543 rs890972 chr5:462465 C/A cg24955955 chr5:415729 AHRR 0.32 6.63 0.34 1.28e-10 Cystic fibrosis severity; LIHC cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg04025307 chr7:1156635 C7orf50 0.56 9.25 0.45 2.48e-18 Longevity;Endometriosis; LIHC cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg17691542 chr6:26056736 HIST1H1C 0.44 6.54 0.33 2.27e-10 Height; LIHC cis rs4268898 0.662 rs9917355 chr2:24433400 C/T cg06627628 chr2:24431161 ITSN2 -0.73 -9.61 -0.46 1.67e-19 Asthma; LIHC cis rs55823223 0.503 rs9906971 chr17:73848477 A/G cg19302996 chr17:73780495 UNK -0.54 -6.71 -0.34 8.24e-11 Psoriasis; LIHC cis rs1395 0.634 rs62130713 chr2:27525661 A/G cg22903471 chr2:27725779 GCKR -0.4 -5.9 -0.3 8.7e-9 Blood metabolite levels; LIHC cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg10360323 chr17:41437877 NA 0.4 5.97 0.31 5.87e-9 Menopause (age at onset); LIHC cis rs11626933 1.000 rs3825661 chr14:90767607 C/T cg04374321 chr14:90722782 PSMC1 -0.49 -6.86 -0.35 3.23e-11 Gut microbiota (bacterial taxa); LIHC cis rs2070488 0.965 rs7373828 chr3:38524311 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 16.09 0.66 8.95e-44 Electrocardiographic conduction measures; LIHC cis rs67460515 0.563 rs9883566 chr3:160770323 C/T cg03342759 chr3:160939853 NMD3 0.56 7.98 0.4 2.16e-14 Parkinson's disease; LIHC cis rs6604026 0.740 rs10782946 chr1:93352669 G/A cg17283838 chr1:93427260 FAM69A -0.42 -5.8 -0.3 1.48e-8 Multiple sclerosis; LIHC cis rs6964587 0.967 rs7783414 chr7:91785957 C/T cg17063962 chr7:91808500 NA 1.04 21.69 0.76 3.13e-66 Breast cancer; LIHC cis rs240764 0.578 rs1414734 chr6:101201823 T/C cg09795085 chr6:101329169 ASCC3 0.43 6.39 0.33 5.3e-10 Neuroticism; LIHC cis rs155076 1.000 rs658244 chr13:21850976 T/C cg11317459 chr13:21872234 NA -1.16 -13.14 -0.58 3.16e-32 White matter hyperintensity burden; LIHC cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7523273 0.927 rs1891423 chr1:207931913 G/A cg22525895 chr1:207977042 MIR29B2 0.69 10.64 0.5 4.98e-23 Schizophrenia; LIHC trans rs61931739 0.534 rs4365131 chr12:34053308 T/C cg26384229 chr12:38710491 ALG10B 0.47 6.62 0.34 1.36e-10 Morning vs. evening chronotype; LIHC trans rs7102494 1.000 rs35533964 chr11:129238527 C/A cg00296894 chr2:3685756 COLEC11 0.68 6.07 0.31 3.39e-9 Breast cancer; LIHC trans rs1814175 0.669 rs12364577 chr11:49707361 A/C cg18944383 chr4:111397179 ENPEP 0.24 6.14 0.32 2.25e-9 Height; LIHC cis rs1789 0.786 rs6414768 chr4:15695363 A/G cg21329975 chr4:15471214 CC2D2A -0.4 -5.89 -0.3 9.39e-9 Blood protein levels; LIHC trans rs911555 0.755 rs12436729 chr14:103929889 G/C cg17675199 chr6:35436792 RPL10A -0.44 -8.99 -0.44 1.74e-17 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.894 rs2694639 chr2:61595291 G/A cg15711740 chr2:61764176 XPO1 0.42 5.76 0.3 1.89e-8 Tuberculosis; LIHC cis rs992157 0.710 rs12694432 chr2:219082330 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.55 0.59 8.81e-34 Colorectal cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01699524 chr5:7869638 MTRR;FASTKD3 -0.46 -6.14 -0.32 2.3e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3008870 0.792 rs72673729 chr1:67441673 T/TG cg02640540 chr1:67518911 SLC35D1 -0.42 -5.81 -0.3 1.45e-8 Lymphocyte percentage of white cells; LIHC cis rs2730245 0.550 rs2709860 chr7:158651156 A/T cg24397884 chr7:158709396 WDR60 0.42 6.19 0.32 1.74e-9 Height; LIHC cis rs804280 0.662 rs11250164 chr8:11610686 C/T cg05267444 chr8:11627012 NEIL2 0.54 6.96 0.35 1.79e-11 Myopia (pathological); LIHC cis rs1865760 1.000 rs12209482 chr6:25909229 T/G cg03517284 chr6:25882590 NA -0.38 -5.72 -0.3 2.27e-8 Height; LIHC cis rs6545883 0.860 rs6545848 chr2:61461183 G/T cg14146966 chr2:61757674 XPO1 -0.43 -7.22 -0.36 3.31e-12 Tuberculosis; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08711378 chr8:11471054 NA 0.28 6.29 0.32 9.86e-10 Hepatitis; LIHC cis rs7208859 0.573 rs216443 chr17:28931871 A/G cg13385521 chr17:29058706 SUZ12P 0.63 6.3 0.32 9.22e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18382599 chr1:43124310 PPIH 0.43 6.51 0.33 2.6e-10 Lung function (FEV1/FVC); LIHC cis rs911119 0.913 rs3004139 chr20:23578674 C/T cg16589663 chr20:23618590 CST3 -0.69 -7.33 -0.37 1.71e-12 Chronic kidney disease; LIHC cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg26913058 chr16:419975 MRPL28 -0.5 -6.99 -0.35 1.49e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs703842 1.000 rs11172349 chr12:58212528 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.86 13.87 0.6 4.98e-35 Multiple sclerosis; LIHC cis rs7216064 1.000 rs8067892 chr17:65837983 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.74 -0.47 6.22e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2882877 0.560 rs11568351 chr2:190445194 C/G cg10752008 chr2:190445175 SLC40A1 -0.63 -7.89 -0.39 4.23e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs36051895 0.658 rs10975029 chr9:5251068 T/C cg02405213 chr9:5042618 JAK2 -0.64 -10.58 -0.5 7.81e-23 Pediatric autoimmune diseases; LIHC cis rs2280018 0.963 rs12928424 chr16:15150773 C/G cg27102117 chr16:15229624 NA 0.28 6.19 0.32 1.68e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2204008 0.747 rs11514040 chr12:38201040 G/A cg13010199 chr12:38710504 ALG10B 0.5 5.9 0.3 8.83e-9 Bladder cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09720207 chr12:54400125 NA 0.46 6.23 0.32 1.36e-9 Lung function (FEV1/FVC); LIHC cis rs9467773 1.000 rs6933176 chr6:26540178 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.73 0.6 1.84e-34 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg20607798 chr8:58055168 NA 0.66 8.05 0.4 1.35e-14 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg11764359 chr7:65958608 NA 0.6 6.38 0.33 5.71e-10 Diabetic kidney disease; LIHC cis rs8084351 0.546 rs11664095 chr18:50763183 A/G cg24270629 chr18:50823537 DCC -0.46 -6.7 -0.34 8.41e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg03806693 chr22:41940476 POLR3H 1.11 12.98 0.57 1.32e-31 Vitiligo; LIHC trans rs916888 0.821 rs199512 chr17:44857352 T/C cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs8114671 0.662 rs6058146 chr20:33540529 A/G cg07148914 chr20:33460835 GGT7 0.64 9.88 0.47 2.1e-20 Height; LIHC cis rs477692 0.549 rs7098548 chr10:131455028 A/G cg19680672 chr10:131412579 MGMT 0.42 6.38 0.33 5.85e-10 Response to temozolomide; LIHC cis rs4853012 0.838 rs12619982 chr2:74356022 G/A cg19729930 chr2:74357872 NA 0.86 20.08 0.74 8.69e-60 Gestational age at birth (maternal effect); LIHC cis rs1580019 0.885 rs4580942 chr7:32496435 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.8 0.54 3.41e-27 Cognitive ability; LIHC cis rs74377301 1 rs74377301 chr7:123232495 C/T cg03229431 chr7:123269106 ASB15 -0.49 -9.86 -0.47 2.35e-20 Left ventricular obstructive tract defect (inherited effect); LIHC cis rs1144333 0.655 rs4949681 chr1:76409828 C/T cg10523679 chr1:76189770 ACADM 0.46 6.29 0.32 9.93e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs17433710 0.543 rs10799865 chr1:162651824 C/G cg01063088 chr1:162760584 HSD17B7 0.45 6.19 0.32 1.76e-9 Dupuytren's disease; LIHC cis rs7582180 0.629 rs4851296 chr2:100949570 T/C cg14675211 chr2:100938903 LONRF2 0.53 8.58 0.42 3.45e-16 Intelligence (multi-trait analysis); LIHC cis rs2933343 0.630 rs75824035 chr3:128652985 T/C cg25356066 chr3:128598488 ACAD9 0.53 7.4 0.37 1.08e-12 IgG glycosylation; LIHC cis rs597539 0.652 rs507520 chr11:68666054 C/T cg06028808 chr11:68637592 NA 0.44 5.76 0.3 1.88e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7772486 0.754 rs6937661 chr6:146113299 T/C cg05347473 chr6:146136440 FBXO30 -0.39 -6.15 -0.32 2.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs968567 0.539 rs174560 chr11:61581764 T/C cg27386326 chr11:61587980 NA 0.71 15.31 0.64 1.16e-40 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs1707322 1.000 rs785517 chr1:46567535 A/T cg06784218 chr1:46089804 CCDC17 -0.4 -7.2 -0.36 3.96e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.964 rs796773 chr1:46564475 C/T cg03146154 chr1:46216737 IPP -0.45 -7.23 -0.36 3.2e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs35306767 0.903 rs11253493 chr10:936931 T/C cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs17854409 0.881 rs1046784 chr20:61472808 G/C cg07645718 chr20:61493192 TCFL5 0.79 6.54 0.33 2.28e-10 Obesity-related traits; LIHC cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.59 -0.56 4.11e-30 Alzheimer's disease; LIHC cis rs6701037 0.681 rs34370567 chr1:175131340 C/T cg00958927 chr1:175162553 KIAA0040 -0.37 -6.22 -0.32 1.48e-9 Alcohol dependence; LIHC cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg13763550 chr16:4524223 NMRAL1;HMOX2 0.46 6.65 0.34 1.17e-10 Schizophrenia; LIHC cis rs9611565 1.000 rs9611565 chr22:41767486 T/C cg06481639 chr22:41940642 POLR3H -0.56 -5.87 -0.3 1.03e-8 Vitiligo; LIHC cis rs9911578 0.967 rs302842 chr17:56728102 C/G cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg03806693 chr22:41940476 POLR3H 1.05 12.79 0.57 7.17e-31 Vitiligo; LIHC cis rs7917772 0.503 rs11191330 chr10:104306160 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 12.5 0.56 8.71e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11971779 0.680 rs6978680 chr7:139112048 A/G cg07862535 chr7:139043722 LUC7L2 -0.6 -10.37 -0.49 4.42e-22 Diisocyanate-induced asthma; LIHC cis rs7618501 0.521 rs2883059 chr3:49902160 C/T cg05623727 chr3:50126028 RBM5 -0.35 -5.87 -0.3 1.01e-8 Intelligence (multi-trait analysis); LIHC cis rs2455799 0.574 rs2455798 chr3:15700505 G/C cg16303742 chr3:15540471 COLQ -0.35 -6.0 -0.31 5.14e-9 Mean platelet volume; LIHC cis rs35306767 0.903 rs35637113 chr10:874149 G/C cg26597838 chr10:835615 NA 1.2 13.91 0.6 3.69e-35 Eosinophil percentage of granulocytes; LIHC cis rs344364 0.511 rs1742473 chr16:1953095 T/C cg26897989 chr16:1907736 C16orf73 -0.47 -5.83 -0.3 1.31e-8 Glomerular filtration rate in chronic kidney disease; LIHC cis rs7833790 0.660 rs7839178 chr8:82763479 A/G cg02079420 chr8:82753780 SNX16 -0.37 -6.65 -0.34 1.17e-10 Diastolic blood pressure; LIHC cis rs9814567 0.858 rs4955548 chr3:134341060 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.61 -9.98 -0.47 9.67e-21 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4555082 0.834 rs2735825 chr14:105710900 G/A cg06808227 chr14:105710500 BRF1 -0.49 -6.06 -0.31 3.63e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs7116495 1.000 rs607446 chr11:71789252 G/A cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs965469 1.000 rs6051747 chr20:3307945 T/C cg25506879 chr20:3388711 C20orf194 -0.55 -6.74 -0.34 6.9e-11 IFN-related cytopenia; LIHC cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg23149560 chr2:74406255 MOBKL1B 0.41 5.75 0.3 2.02e-8 Gestational age at birth (maternal effect); LIHC cis rs17685 0.712 rs1637049 chr7:75729975 C/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.17 -0.32 1.93e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs240764 0.817 rs6922219 chr6:101153907 G/C cg09795085 chr6:101329169 ASCC3 -0.52 -7.17 -0.36 4.63e-12 Neuroticism; LIHC cis rs4665809 1.000 rs4665823 chr2:26312723 A/G cg27170947 chr2:26402098 FAM59B -0.62 -7.72 -0.39 1.27e-13 Gut microbiome composition (summer); LIHC cis rs4319547 0.737 rs7964138 chr12:122950375 A/G cg05707623 chr12:122985044 ZCCHC8 -0.59 -7.81 -0.39 7.2e-14 Body mass index; LIHC cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs3749237 0.964 rs1799845 chr3:49847623 A/G cg03060546 chr3:49711283 APEH 0.4 6.28 0.32 1.04e-9 Resting heart rate; LIHC cis rs55665837 1.000 rs11023227 chr11:14459087 T/C cg19336497 chr11:14380999 RRAS2 -0.44 -7.99 -0.4 2.15e-14 Vitamin D levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25506325 chr7:2093962 MAD1L1 0.43 6.4 0.33 5.19e-10 Longevity; LIHC trans rs2727020 0.521 rs7131163 chr11:49574774 C/T cg15704280 chr7:45808275 SEPT13 -0.8 -12.07 -0.55 3.42e-28 Coronary artery disease; LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg23752198 chr20:30311963 BCL2L1 -0.55 -6.7 -0.34 8.84e-11 Bronchial neuroendocrine tumor; LIHC cis rs7927771 0.965 rs56400411 chr11:47586376 T/G cg18512352 chr11:47633146 NA -0.26 -6.07 -0.31 3.45e-9 Subjective well-being; LIHC cis rs1577917 0.958 rs13219504 chr6:86556917 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.44 -0.37 8.35e-13 Response to antipsychotic treatment; LIHC cis rs2180341 0.920 rs1073932 chr6:127682009 G/T cg27446573 chr6:127587934 RNF146 1.05 16.49 0.67 2.21e-45 Breast cancer; LIHC cis rs2279817 0.863 rs13375960 chr1:18016687 C/T cg21791023 chr1:18019539 ARHGEF10L -0.68 -7.99 -0.4 2.06e-14 Neuroticism; LIHC cis rs75920871 0.588 rs688456 chr11:116722551 G/T cg04087571 chr11:116723030 SIK3 -0.29 -5.72 -0.3 2.34e-8 Subjective well-being; LIHC cis rs6665290 0.870 rs1045289 chr1:227178713 C/T cg10327440 chr1:227177885 CDC42BPA -1.19 -31.54 -0.86 3e-103 Myeloid white cell count; LIHC cis rs10861342 1.000 rs703683 chr12:105567135 T/C cg23923672 chr12:105501055 KIAA1033 0.64 7.64 0.38 2.26e-13 IgG glycosylation; LIHC cis rs35306767 0.903 rs12249828 chr10:894838 C/T cg20503657 chr10:835505 NA 1.05 12.28 0.55 5.87e-29 Eosinophil percentage of granulocytes; LIHC cis rs9649465 0.967 rs13225110 chr7:123340849 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.18e-15 Migraine; LIHC cis rs796364 1.000 rs281760 chr2:200787804 A/G cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.67e-9 Schizophrenia; LIHC cis rs8062405 1.000 rs62036624 chr16:28839930 G/T cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.27e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2574704 0.603 rs3856802 chr3:11667714 C/T cg15876825 chr3:11651881 VGLL4 -0.41 -6.73 -0.34 7.34e-11 Body mass index; LIHC cis rs1728785 0.688 rs7203363 chr16:68587692 T/A cg02972257 chr16:68554789 NA -0.53 -5.93 -0.31 7.57e-9 Ulcerative colitis; LIHC trans rs9641123 0.643 rs6975603 chr7:93206375 A/C cg09745688 chr16:2908918 PRSS22 -0.37 -6.38 -0.33 5.87e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs9457247 1.000 rs436707 chr6:167388843 T/C cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs2427308 0.607 rs1741635 chr20:60938197 C/G cg09594475 chr20:60884601 LAMA5 -0.53 -6.28 -0.32 1.06e-9 Colorectal cancer; LIHC cis rs7618501 0.521 rs11709573 chr3:49956628 C/T cg21467203 chr3:49911342 NA -0.58 -10.57 -0.5 8.47e-23 Intelligence (multi-trait analysis); LIHC cis rs739401 0.572 rs404629 chr11:3077025 A/G cg08508325 chr11:3079039 CARS -0.35 -7.38 -0.37 1.2e-12 Longevity; LIHC cis rs6964587 1.000 rs417 chr7:91581121 C/A cg17063962 chr7:91808500 NA -1.03 -20.55 -0.74 1.15e-61 Breast cancer; LIHC cis rs7044106 0.791 rs4837792 chr9:123483559 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.78 0.39 8.7e-14 Hip circumference adjusted for BMI; LIHC cis rs787274 1.000 rs787298 chr9:115542206 C/T cg13803584 chr9:115635662 SNX30 -0.57 -6.31 -0.32 8.49e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs6582630 0.598 rs10880645 chr12:38556172 G/A cg05848834 chr11:43543746 NA -0.3 -6.07 -0.31 3.49e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs17125944 0.686 rs6572868 chr14:53325090 C/T cg00686598 chr14:53173677 PSMC6 -0.82 -9.03 -0.44 1.25e-17 Alzheimer's disease (late onset); LIHC cis rs12477438 0.520 rs12621007 chr2:99791946 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 14.26 0.61 1.52e-36 Chronic sinus infection; LIHC cis rs7772486 0.738 rs9485039 chr6:146319387 C/T cg23711669 chr6:146136114 FBXO30 0.63 10.29 0.49 8.39e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs2183112 chr6:8528212 G/A cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs17381785 0.545 rs1494947 chr4:14969983 T/G cg12377275 chr4:15005593 CPEB2 0.74 11.27 0.52 2.83e-25 Urate levels in overweight individuals; LIHC cis rs2204008 0.642 rs11169812 chr12:37995530 G/A cg26384229 chr12:38710491 ALG10B -0.51 -7.01 -0.35 1.28e-11 Bladder cancer; LIHC cis rs2749592 0.550 rs9733309 chr10:37882405 G/A cg25427524 chr10:38739819 LOC399744 0.57 10.29 0.49 7.98e-22 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2404602 0.716 rs7169394 chr15:76913274 G/A cg03037974 chr15:76606532 NA 0.74 14.33 0.61 8.31e-37 Blood metabolite levels; LIHC cis rs4561483 0.801 rs33623 chr16:12007435 A/G cg08843971 chr16:11963173 GSPT1 0.44 8.72 0.43 1.26e-16 Testicular germ cell tumor; LIHC cis rs950169 0.922 rs12910334 chr15:84958318 G/A cg17507749 chr15:85114479 UBE2QP1 0.72 8.32 0.41 2.12e-15 Schizophrenia; LIHC cis rs10789491 1.000 rs7547522 chr1:47179918 C/G cg15501359 chr1:47185051 KIAA0494 0.78 11.05 0.51 1.79e-24 Response to hepatitis C treatment; LIHC cis rs9596863 0.898 rs67601073 chr13:54322196 A/T ch.13.53330881F chr13:54432880 NA 0.42 5.73 0.3 2.19e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.13 -0.44 6.13e-18 Bipolar disorder; LIHC cis rs12744310 1.000 rs56096486 chr1:41771230 A/C cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs2243480 1.000 rs781142 chr7:65438778 C/T cg10756647 chr7:56101905 PSPH 1.1 13.62 0.59 4.65e-34 Diabetic kidney disease; LIHC cis rs3806843 1.000 rs10477034 chr5:140169730 A/G cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.22e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2292096 0.636 rs6658395 chr1:200748760 C/T cg11814564 chr1:200748674 CAMSAP1L1 -0.55 -10.56 -0.5 9.47e-23 Epilepsy; LIHC cis rs12478296 0.901 rs73007142 chr2:243010852 T/C cg05760424 chr2:242988095 NA -0.54 -7.28 -0.37 2.37e-12 Obesity-related traits; LIHC cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs2979489 0.773 rs2915617 chr8:30272310 C/G cg26383811 chr8:30366931 RBPMS 0.47 7.71 0.38 1.41e-13 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs6952808 0.771 rs10265944 chr7:1918337 C/T cg02951883 chr7:2050386 MAD1L1 -0.56 -8.45 -0.42 8.44e-16 Bipolar disorder and schizophrenia; LIHC cis rs6963495 0.818 rs73190167 chr7:105160418 A/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs903552 0.673 rs4965878 chr15:102009589 C/T cg06707286 chr15:102010195 PCSK6 -0.55 -7.78 -0.39 8.54e-14 Diabetic kidney disease; LIHC cis rs2806561 0.704 rs856510 chr1:23524407 A/C cg12483005 chr1:23474871 LUZP1 0.47 7.24 0.36 3.01e-12 Height; LIHC cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg27297192 chr10:134578999 INPP5A 0.52 7.81 0.39 6.95e-14 Migraine; LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC trans rs11098499 0.697 rs28458294 chr4:120238924 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.57 0.42 3.6e-16 Corneal astigmatism; LIHC cis rs11122272 0.735 rs2739516 chr1:231505527 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg03806693 chr22:41940476 POLR3H 0.97 10.23 0.48 1.33e-21 Crohn's disease;Inflammatory bowel disease; LIHC cis rs3791556 0.504 rs1001285 chr2:240107814 A/G cg03281426 chr2:240109471 HDAC4 0.46 8.51 0.42 5.74e-16 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1048238 0.506 rs598371 chr1:16212739 G/A cg00529422 chr1:16285251 ZBTB17 0.34 6.54 0.33 2.22e-10 Systolic blood pressure; LIHC cis rs7666738 0.546 rs1863602 chr4:98909304 T/C cg05340658 chr4:99064831 C4orf37 0.49 6.51 0.33 2.66e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg06481639 chr22:41940642 POLR3H -0.64 -6.65 -0.34 1.14e-10 Vitiligo; LIHC cis rs735860 0.726 rs209510 chr6:53202035 T/C cg10236188 chr6:53219634 NA 0.42 7.63 0.38 2.42e-13 Glaucoma; LIHC cis rs116248771 0.739 rs73156489 chr3:158414026 C/T cg16708174 chr3:158430962 RARRES1 0.49 6.48 0.33 3.25e-10 diarrhoeal disease at age 2; LIHC cis rs7100689 0.646 rs1340380 chr10:82115619 T/C cg00277334 chr10:82204260 NA -0.57 -7.02 -0.35 1.22e-11 Post bronchodilator FEV1; LIHC cis rs9611565 0.559 rs8139993 chr22:41995335 T/C cg03806693 chr22:41940476 POLR3H -0.84 -9.3 -0.45 1.71e-18 Vitiligo; LIHC cis rs1707322 1.000 rs4074225 chr1:46392364 G/C cg03146154 chr1:46216737 IPP 0.47 7.47 0.37 6.87e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2153535 0.580 rs718503 chr6:8527463 A/T cg07606381 chr6:8435919 SLC35B3 0.79 11.52 0.53 3.67e-26 Motion sickness; LIHC cis rs2204008 0.749 rs10880692 chr12:38592918 C/G cg13010199 chr12:38710504 ALG10B -0.59 -7.09 -0.36 7.59e-12 Bladder cancer; LIHC cis rs2070488 0.775 rs2051213 chr3:38560254 C/T cg02352945 chr3:38496316 LOC100128640;ACVR2B 0.41 5.83 0.3 1.29e-8 Electrocardiographic conduction measures; LIHC cis rs9814567 1.000 rs10804632 chr3:134294501 T/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.19 -0.32 1.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12744310 1.000 rs7513682 chr1:41772167 T/C cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg07092213 chr7:1199455 ZFAND2A -0.43 -6.25 -0.32 1.22e-9 Longevity;Endometriosis; LIHC cis rs10256972 0.967 rs4723338 chr7:1036241 A/G cg07308232 chr7:1071921 C7orf50 -0.47 -7.8 -0.39 7.41e-14 Longevity;Endometriosis; LIHC cis rs1552244 0.882 rs17050699 chr3:10037167 G/A cg13047869 chr3:10149882 C3orf24 0.43 6.03 0.31 4.17e-9 Alzheimer's disease; LIHC cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg18305652 chr10:134549665 INPP5A 0.51 8.21 0.41 4.46e-15 Migraine; LIHC cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg00750074 chr16:89608354 SPG7 -0.54 -8.72 -0.43 1.23e-16 Multiple myeloma (IgH translocation); LIHC cis rs6582630 0.519 rs11181294 chr12:38312787 C/T cg26384229 chr12:38710491 ALG10B 0.59 8.18 0.4 5.74e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs10248839 0.518 rs34011864 chr7:29698499 G/A cg19413766 chr7:29689036 LOC646762 -0.62 -6.36 -0.33 6.62e-10 Facial emotion recognition (angry faces); LIHC cis rs748404 0.604 rs2278857 chr15:43632549 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.57 9.23 0.45 2.93e-18 Lung cancer; LIHC cis rs875971 0.642 rs35526611 chr7:66094008 C/T cg11764359 chr7:65958608 NA -0.72 -10.79 -0.5 1.54e-23 Aortic root size; LIHC cis rs832190 1 rs832190 chr3:63842629 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.55 8.09 0.4 1.02e-14 Schizophrenia; LIHC cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg17971929 chr21:40555470 PSMG1 0.8 9.65 0.46 1.16e-19 Cognitive function; LIHC trans rs2665103 0.715 rs11639440 chr15:82571046 G/A cg18393722 chr15:85113863 UBE2QP1 -0.45 -7.12 -0.36 6.54e-12 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15001132 chr13:25875890 NUPL1 -0.46 -6.38 -0.33 5.79e-10 Pancreatic cancer; LIHC trans rs35110281 0.782 rs1584917 chr21:45042365 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.27 0.32 1.08e-9 Mean corpuscular volume; LIHC cis rs9733 0.596 rs12086630 chr1:150650955 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.2 0.32 1.67e-9 Tonsillectomy; LIHC cis rs1008375 1.000 rs28693609 chr4:17645233 C/T cg16339924 chr4:17578868 LAP3 0.44 6.22 0.32 1.49e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs990171 0.607 rs10153578 chr2:102764609 C/T cg22835712 chr2:102737379 NA -0.51 -7.23 -0.36 3.27e-12 Lymphocyte counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01506766 chr13:46626746 ZC3H13 -0.47 -6.2 -0.32 1.61e-9 Pancreatic cancer; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs908922 0.676 rs477621 chr1:152486252 T/C cg20991723 chr1:152506922 NA 0.49 8.34 0.41 1.78e-15 Hair morphology; LIHC cis rs1003719 0.715 rs2251952 chr21:38559711 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.63 -9.38 -0.45 9.44e-19 Eye color traits; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg01420254 chr6:26195488 NA 0.51 5.85 0.3 1.17e-8 Gout;Renal underexcretion gout; LIHC cis rs9814567 1.000 rs1917130 chr3:134313773 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.22 0.32 1.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs75908454 1.000 rs117148598 chr6:169832846 G/T cg19338460 chr6:170058176 WDR27 -0.86 -7.77 -0.39 9.33e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg22963979 chr7:1858916 MAD1L1 -0.38 -5.92 -0.3 7.81e-9 Bipolar disorder and schizophrenia; LIHC cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg06634786 chr22:41940651 POLR3H 0.84 9.16 0.44 4.88e-18 Vitiligo; LIHC cis rs2832191 0.791 rs2832187 chr21:30485543 T/C cg24692254 chr21:30365293 RNF160 -0.68 -12.4 -0.56 1.97e-29 Dental caries; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg27220681 chr17:685915 RNMTL1;GLOD4 -0.41 -6.38 -0.33 5.68e-10 Triglycerides; LIHC cis rs9733 0.596 rs12086472 chr1:150697710 G/A cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs7091068 0.707 rs829107 chr10:95418102 C/T cg20715218 chr10:95462985 C10orf4 -0.55 -5.78 -0.3 1.71e-8 Urinary tract infection frequency; LIHC cis rs6951245 0.554 rs4724294 chr7:1139695 G/A cg22907277 chr7:1156413 C7orf50 0.86 8.15 0.4 6.97e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7647973 0.506 rs11920251 chr3:49356671 C/T cg07636037 chr3:49044803 WDR6 0.6 9.59 0.46 1.85e-19 Menarche (age at onset); LIHC cis rs1728785 1.000 rs698716 chr16:68560296 C/T cg02972257 chr16:68554789 NA -0.54 -6.11 -0.31 2.64e-9 Ulcerative colitis; LIHC cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg24209194 chr3:40518798 ZNF619 0.44 6.28 0.32 1.05e-9 Renal cell carcinoma; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg08168689 chr14:76455272 C14orf179 0.45 6.81 0.35 4.28e-11 Alopecia areata; LIHC cis rs60012524 1 rs60012524 chr2:99559117 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.05 -10.81 -0.5 1.22e-23 Chronic sinus infection; LIHC cis rs6089584 0.853 rs1746280 chr20:60577821 C/G cg06108461 chr20:60628389 TAF4 -0.96 -15.13 -0.63 5.85e-40 Body mass index; LIHC cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs655641 0.859 rs648270 chr11:85726818 T/C cg09030501 chr11:85779252 PICALM -0.52 -6.14 -0.32 2.23e-9 Platelet count; LIHC cis rs9814567 0.929 rs9855013 chr3:134240414 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6424115 0.830 rs3003333 chr1:24194014 A/T cg15997130 chr1:24165203 NA -0.43 -8.96 -0.44 2.17e-17 Immature fraction of reticulocytes; LIHC cis rs3736757 0.627 rs9425338 chr1:184646229 T/C cg07817967 chr1:184721222 EDEM3 0.36 5.8 0.3 1.5e-8 Obesity-related traits; LIHC cis rs6446731 0.517 rs2071667 chr4:3269926 C/A cg06533319 chr4:3265114 C4orf44 0.31 5.76 0.3 1.86e-8 Mean platelet volume; LIHC cis rs8062405 0.895 rs56186137 chr16:28825953 A/G cg00204512 chr16:28754710 NA 0.36 6.71 0.34 7.92e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7937890 0.874 rs6486191 chr11:14403739 G/A cg22961513 chr11:14280813 SPON1 -0.43 -6.62 -0.34 1.42e-10 Mitochondrial DNA levels; LIHC cis rs6570726 0.935 rs407721 chr6:145871354 A/C cg23711669 chr6:146136114 FBXO30 0.57 10.03 0.48 6.57e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs12478296 1.000 rs57603292 chr2:243028537 G/A cg01596870 chr19:55963115 NA -0.63 -7.54 -0.38 4.17e-13 Obesity-related traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16895464 chr15:91415119 FURIN -0.49 -6.2 -0.32 1.65e-9 Systolic blood pressure; LIHC cis rs916888 0.821 rs199504 chr17:44861003 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.72 -6.86 -0.35 3.28e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4453791 0.872 rs62244134 chr3:38888764 G/A cg02254461 chr3:39195904 CSRNP1 0.64 5.76 0.3 1.84e-8 Social communication problems; LIHC cis rs1023500 0.573 rs133377 chr22:42466950 C/T cg15557168 chr22:42548783 NA -0.43 -6.75 -0.34 6.53e-11 Schizophrenia; LIHC cis rs7258950 0.751 rs2738464 chr19:11242307 G/C cg07962303 chr19:11253944 NA -0.64 -7.99 -0.4 2.02e-14 Cholesterol, total;LDL cholesterol; LIHC cis rs2404602 0.583 rs3759853 chr15:76587777 C/T cg03037974 chr15:76606532 NA 0.9 23.51 0.79 2.01e-73 Blood metabolite levels; LIHC cis rs9733 0.818 rs12130363 chr1:150688596 T/C cg13175981 chr1:150552382 MCL1 0.52 8.07 0.4 1.17e-14 Tonsillectomy; LIHC cis rs11098499 0.826 rs12511640 chr4:120251248 T/C cg09307838 chr4:120376055 NA 0.71 11.25 0.52 3.29e-25 Corneal astigmatism; LIHC cis rs3106136 0.649 rs4699411 chr4:95299347 T/C cg11021082 chr4:95130006 SMARCAD1 0.36 6.13 0.31 2.43e-9 Capecitabine sensitivity; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.46 0.62 2.68e-37 Prudent dietary pattern; LIHC cis rs703842 0.616 rs10877024 chr12:58226709 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.71 9.92 0.47 1.48e-20 Multiple sclerosis; LIHC cis rs1400745 0.812 rs72678789 chr14:35348201 T/G cg05294307 chr14:35346193 BAZ1A 0.45 7.54 0.38 4.27e-13 Monocyte count; LIHC cis rs6430585 0.527 rs62168836 chr2:136463117 G/A cg07169764 chr2:136633963 MCM6 0.67 8.54 0.42 4.42e-16 Corneal structure; LIHC cis rs10847980 0.590 rs2292131 chr12:123332354 C/T cg25930673 chr12:123319894 HIP1R 1.14 12.88 0.57 3.08e-31 Adiponectin levels; LIHC cis rs3849570 0.695 rs6809528 chr3:81872048 A/C cg07356753 chr3:81810745 GBE1 -0.44 -5.96 -0.31 6.43e-9 Waist circumference;Body mass index; LIHC cis rs2997447 0.894 rs55722280 chr1:26412684 T/C cg19633962 chr1:26362018 EXTL1 -0.59 -6.9 -0.35 2.52e-11 QRS complex (12-leadsum); LIHC cis rs17826219 0.636 rs12946563 chr17:29103166 C/G cg13385521 chr17:29058706 SUZ12P 0.83 8.01 0.4 1.81e-14 Body mass index; LIHC cis rs7772486 0.534 rs34541797 chr6:146205304 A/G cg13319975 chr6:146136371 FBXO30 -0.58 -8.95 -0.44 2.23e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs2479724 0.840 rs10498752 chr6:41768510 T/C cg17623882 chr6:41773611 USP49 0.55 8.64 0.42 2.24e-16 Menarche (age at onset); LIHC cis rs921968 0.541 rs7583449 chr2:219403022 A/C cg02176678 chr2:219576539 TTLL4 -0.57 -7.88 -0.39 4.49e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs3768617 0.510 rs1886501 chr1:183095234 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs921968 0.565 rs35189512 chr2:219628759 T/C cg02985541 chr2:219472218 PLCD4 -0.36 -6.36 -0.33 6.34e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs8062405 0.755 rs62031607 chr16:28631530 A/T cg00204512 chr16:28754710 NA 0.41 6.75 0.34 6.46e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs66569888 0.789 rs17213078 chr2:106734065 G/A cg16099169 chr2:106886729 NA -0.83 -8.85 -0.43 4.94e-17 Facial morphology (factor 23); LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs58688157 0.880 rs12272314 chr11:590648 A/G cg01842473 chr11:617407 IRF7;MUPCDH -0.54 -6.07 -0.31 3.45e-9 Systemic lupus erythematosus; LIHC cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg11301795 chr4:187892539 NA -0.25 -6.63 -0.34 1.29e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17376456 0.877 rs9314101 chr5:93461593 A/T cg25358565 chr5:93447407 FAM172A 1.12 10.35 0.49 5.17e-22 Diabetic retinopathy; LIHC cis rs7208859 0.573 rs60724269 chr17:29113273 G/T cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs2727020 0.636 rs11040368 chr11:49453602 C/A cg15704280 chr7:45808275 SEPT13 -0.94 -18.87 -0.71 6.25e-55 Coronary artery disease; LIHC cis rs898097 0.841 rs12453162 chr17:80859971 C/T cg15664640 chr17:80829946 TBCD -0.75 -11.94 -0.54 1.03e-27 Breast cancer; LIHC cis rs12971120 1.000 rs734559 chr18:72179579 G/A cg25817165 chr18:72167213 CNDP2 -0.71 -12.51 -0.56 7.85e-30 Refractive error; LIHC cis rs7937890 0.904 rs67623158 chr11:14295196 T/C cg02251663 chr11:14281053 SPON1 0.45 6.3 0.32 9e-10 Mitochondrial DNA levels; LIHC cis rs17152411 0.817 rs4478950 chr10:126596425 T/C cg07906193 chr10:126599966 NA 0.46 7.09 0.36 7.76e-12 Height; LIHC cis rs7584330 0.504 rs11890255 chr2:238434605 A/G cg08992911 chr2:238395768 MLPH 0.47 5.73 0.3 2.23e-8 Prostate cancer; LIHC cis rs7520050 0.966 rs4376778 chr1:46288846 C/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.08 0.31 3.26e-9 Red blood cell count;Reticulocyte count; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.56 0.62 1.09e-37 Prudent dietary pattern; LIHC cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.19 0.36 4.22e-12 Bipolar disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11932640 chr4:4861200 MSX1 0.44 6.07 0.31 3.35e-9 Lung function (FEV1/FVC); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg08021833 chr19:5785663 PRR22;DUS3L 0.4 6.11 0.31 2.65e-9 Immature fraction of reticulocytes; LIHC cis rs4073582 0.516 rs1151539 chr11:66031660 C/T cg16950941 chr11:66035639 RAB1B 0.6 9.12 0.44 6.67e-18 Gout; LIHC cis rs4237845 0.837 rs7971877 chr12:58287630 T/G cg04478727 chr12:58166393 METTL1;FAM119B 0.44 5.97 0.31 6.03e-9 Intelligence (multi-trait analysis); LIHC cis rs11758351 1.000 rs2143347 chr6:26198494 C/T cg16070018 chr6:26224392 HIST1H3E 0.53 6.47 0.33 3.33e-10 Gout;Renal underexcretion gout; LIHC cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg13409248 chr3:40428643 ENTPD3 0.4 6.6 0.34 1.53e-10 Renal cell carcinoma; LIHC cis rs3096299 0.900 rs3114867 chr16:89428967 A/C cg08822215 chr16:89438651 ANKRD11 -0.43 -6.87 -0.35 3.06e-11 Multiple myeloma (IgH translocation); LIHC cis rs7089973 0.604 rs2420067 chr10:116590348 A/G cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.38 0.8 8.94e-77 Prudent dietary pattern; LIHC cis rs2832191 0.703 rs2853827 chr21:30443596 T/C cg08807101 chr21:30365312 RNF160 0.79 11.72 0.54 6.68e-27 Dental caries; LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs2549003 0.811 rs10035166 chr5:131823927 C/T cg21138405 chr5:131827807 IRF1 -0.34 -7.03 -0.36 1.12e-11 Asthma (sex interaction); LIHC cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.8 0.3 1.54e-8 Menopause (age at onset); LIHC cis rs1823913 0.927 rs13025919 chr2:192124901 T/C cg12404831 chr2:192114017 MYO1B 0.32 6.52 0.33 2.46e-10 Obesity-related traits; LIHC cis rs10508774 1.000 rs1984071 chr10:32910806 G/T cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10791323 0.546 rs55801927 chr11:133713094 A/C cg06766960 chr11:133703094 NA -0.65 -10.92 -0.51 5.15e-24 Childhood ear infection; LIHC cis rs2153535 0.541 rs6905934 chr6:8440043 C/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs4700695 0.841 rs251608 chr5:65247893 C/T cg21114390 chr5:65439923 SFRS12 0.49 6.63 0.34 1.3e-10 Facial morphology (factor 19); LIHC trans rs2243480 1.000 rs465359 chr7:65558164 C/T cg10756647 chr7:56101905 PSPH 1.06 13.26 0.58 1.11e-32 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs9841335 chr3:40475858 G/A cg18306943 chr3:40428807 ENTPD3 0.34 6.06 0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs6831352 0.918 rs6813415 chr4:100048509 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs10779751 1.000 rs12032364 chr1:11286872 G/T cg08854313 chr1:11322531 MTOR 0.82 11.59 0.53 2.05e-26 Body mass index; LIHC cis rs9948 0.786 rs62152765 chr2:97440420 G/A cg01990225 chr2:97406019 LMAN2L -0.72 -6.27 -0.32 1.12e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg15691649 chr6:25882328 NA -0.54 -7.83 -0.39 6.33e-14 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.3.96438232F chr3:94955542 NA -0.36 -6.79 -0.34 5e-11 Cognitive function; LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.69 0.46 9.05e-20 Bipolar disorder; LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg09177884 chr7:1199841 ZFAND2A -0.45 -6.52 -0.33 2.58e-10 Longevity;Endometriosis; LIHC cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1215050 0.846 rs783923 chr4:98968686 C/T cg05340658 chr4:99064831 C4orf37 -0.41 -5.97 -0.31 5.97e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs853679 0.517 rs6922063 chr6:28094366 G/A cg23485639 chr6:28045615 ZNF165 0.45 6.03 0.31 4.28e-9 Depression; LIHC cis rs13191362 1.000 rs13210412 chr6:163019478 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.62 5.89 0.3 9.14e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4665809 0.941 rs1434079 chr2:26284670 C/G cg27170947 chr2:26402098 FAM59B -0.63 -7.79 -0.39 8.3e-14 Gut microbiome composition (summer); LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg12034118 chr1:209979487 IRF6 0.47 8.07 0.4 1.18e-14 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC trans rs7178375 1.000 rs4779797 chr15:31208425 C/T cg04373760 chr16:53404718 NA -0.59 -7.92 -0.39 3.31e-14 Hypertriglyceridemia; LIHC cis rs600806 0.888 rs443345 chr1:109849254 A/G cg02415029 chr1:110025642 ATXN7L2 -0.49 -5.94 -0.31 6.87e-9 Intelligence (multi-trait analysis); LIHC cis rs595982 0.527 rs17272673 chr19:49362992 C/A cg15549821 chr19:49342101 PLEKHA4 -0.7 -6.69 -0.34 8.91e-11 Red cell distribution width; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.71 -0.34 8.29e-11 Total body bone mineral density; LIHC cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg25894440 chr7:65020034 NA -0.51 -5.97 -0.31 5.96e-9 Diabetic kidney disease; LIHC cis rs7208859 0.623 rs11651858 chr17:29170718 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs6088590 0.687 rs8115656 chr20:33282780 G/C cg24642439 chr20:33292090 TP53INP2 0.49 6.83 0.35 3.87e-11 Coronary artery disease; LIHC cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg20887711 chr4:1340912 KIAA1530 -0.77 -12.58 -0.56 4.43e-30 Longevity; LIHC cis rs7635838 0.751 rs9811658 chr3:11395833 A/G cg00170343 chr3:11313890 ATG7 0.49 7.73 0.39 1.19e-13 HDL cholesterol; LIHC cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.59 -8.73 -0.43 1.12e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg02951883 chr7:2050386 MAD1L1 0.68 11.1 0.51 1.15e-24 Bipolar disorder and schizophrenia; LIHC cis rs11864453 0.682 rs10852509 chr16:72026010 G/A cg01557791 chr16:72042693 DHODH -0.41 -6.45 -0.33 3.8e-10 Fibrinogen levels; LIHC cis rs7296418 0.599 rs2277343 chr12:123794450 A/T cg00376283 chr12:123451042 ABCB9 0.62 10.31 0.49 6.98e-22 Platelet count; LIHC cis rs7474896 0.537 rs1208591 chr10:38212502 A/T cg25427524 chr10:38739819 LOC399744 -0.44 -5.72 -0.3 2.33e-8 Obesity (extreme); LIHC cis rs8062405 1.000 rs62036617 chr16:28827498 T/C cg16576597 chr16:28551801 NUPR1 0.37 6.11 0.31 2.74e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs875971 0.545 rs73142233 chr7:65686280 T/A cg26939375 chr7:64535504 NA 0.39 6.21 0.32 1.57e-9 Aortic root size; LIHC cis rs78456975 0.689 rs10194040 chr2:1543293 T/G cg01028140 chr2:1542097 TPO -0.62 -8.01 -0.4 1.85e-14 Placebo response in major depressive disorder (% change in symptom score); LIHC trans rs11098499 0.955 rs35916640 chr4:120155852 T/C cg25214090 chr10:38739885 LOC399744 0.54 8.2 0.41 4.76e-15 Corneal astigmatism; LIHC cis rs7534824 0.625 rs55693426 chr1:101466859 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 7.29 0.37 2.2e-12 Refractive astigmatism; LIHC cis rs559928 0.597 rs2186572 chr11:63895887 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.75 6.63 0.34 1.33e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs11252926 0.583 rs4881333 chr10:519164 G/C cg09445902 chr10:555545 DIP2C -0.36 -5.71 -0.3 2.44e-8 Psychosis in Alzheimer's disease; LIHC cis rs9486715 1.000 rs6905568 chr6:97066382 T/C cg18709589 chr6:96969512 KIAA0776 -0.35 -6.05 -0.31 3.81e-9 Headache; LIHC cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs11758351 1.000 rs77961951 chr6:26186075 A/G cg06951627 chr6:26196580 NA 0.54 5.92 0.3 7.89e-9 Gout;Renal underexcretion gout; LIHC cis rs16828019 0.852 rs34979067 chr1:41543084 G/A cg20697417 chr1:41786797 NA 0.31 5.86 0.3 1.09e-8 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.658 rs6658066 chr1:150918937 T/G cg17724175 chr1:150552817 MCL1 0.4 7.78 0.39 8.7e-14 Melanoma; LIHC cis rs72653721 0.689 rs4435941 chr6:11061518 C/T cg13562911 chr6:11044106 ELOVL2 0.51 7.51 0.38 5.15e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs7617773 0.743 rs71323397 chr3:48374874 A/G cg11946769 chr3:48343235 NME6 0.91 11.6 0.53 1.83e-26 Coronary artery disease; LIHC cis rs317689 0.559 rs710794 chr12:69747177 C/T cg20891283 chr12:69753455 YEATS4 0.61 5.96 0.31 6.39e-9 Response to diuretic therapy; LIHC cis rs6831256 1.000 rs6831256 chr4:3473139 A/G cg08741688 chr4:3415352 RGS12 -0.45 -7.15 -0.36 5.2e-12 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg00101154 chr16:420108 MRPL28 -0.57 -8.26 -0.41 3.23e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs1801251 1.000 rs778166 chr2:233664097 A/T cg08000102 chr2:233561755 GIGYF2 0.75 11.36 0.52 1.39e-25 Coronary artery disease; LIHC cis rs8062405 1.000 rs55830740 chr16:28847149 G/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg06420487 chr17:61919686 SMARCD2 0.43 5.84 0.3 1.2e-8 Height; LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg14004847 chr7:1930337 MAD1L1 -0.46 -6.65 -0.34 1.13e-10 Bipolar disorder and schizophrenia; LIHC cis rs35306767 0.761 rs11253538 chr10:1011166 C/T cg26597838 chr10:835615 NA 0.96 9.22 0.45 3.12e-18 Eosinophil percentage of granulocytes; LIHC cis rs8010715 0.816 rs762093 chr14:24591918 G/C cg23112188 chr14:24563095 PCK2 -0.29 -5.96 -0.31 6.21e-9 IgG glycosylation; LIHC cis rs7700895 0.737 rs1043381 chr5:95221337 C/T cg10483112 chr5:95245456 ELL2 -0.33 -5.95 -0.31 6.67e-9 IgG glycosylation; LIHC trans rs4843747 0.671 rs13334603 chr16:88116016 T/C cg26811252 chr16:29126840 RRN3P2 0.42 6.92 0.35 2.18e-11 Menopause (age at onset); LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs12711979 0.765 rs897069 chr2:3818947 C/T cg17052675 chr2:3827356 NA 0.42 7.23 0.36 3.2e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs10788264 0.504 rs4751886 chr10:124020396 T/C cg04162153 chr10:124029871 BTBD16 0.42 5.82 0.3 1.33e-8 Total body bone mineral density; LIHC cis rs10464366 0.544 rs12668821 chr7:39167846 T/A cg15212455 chr7:39170539 POU6F2 0.48 8.49 0.42 6.22e-16 IgG glycosylation; LIHC cis rs7927771 0.725 rs11039265 chr11:47523214 C/A cg18512352 chr11:47633146 NA -0.26 -6.08 -0.31 3.18e-9 Subjective well-being; LIHC cis rs9733 0.565 rs7524620 chr1:150616699 C/T cg15448220 chr1:150897856 SETDB1 -0.39 -6.2 -0.32 1.59e-9 Tonsillectomy; LIHC cis rs559928 0.606 rs11605856 chr11:63925528 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.75 7.3 0.37 1.97e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs10791323 0.517 rs1120246 chr11:133745212 G/A cg06766960 chr11:133703094 NA -0.41 -6.14 -0.32 2.31e-9 Childhood ear infection; LIHC cis rs3770081 1.000 rs12617717 chr2:86342303 G/A cg01119172 chr2:86362222 SNORD94;PTCD3 0.45 6.11 0.31 2.74e-9 Facial emotion recognition (sad faces); LIHC cis rs875971 0.660 rs801211 chr7:66015689 T/G cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs6752107 1.000 rs3828309 chr2:234180410 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 -0.54 -8.11 -0.4 8.96e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.89 0.57 2.82e-31 Prudent dietary pattern; LIHC trans rs2262909 0.962 rs12610034 chr19:22314528 G/A cg05197062 chr11:11642011 GALNTL4 0.46 6.68 0.34 9.74e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2404602 1.000 rs2896954 chr15:76851692 C/A cg03037974 chr15:76606532 NA 0.75 15.1 0.63 7.91e-40 Blood metabolite levels; LIHC cis rs826838 0.586 rs10880753 chr12:38628147 C/A cg26384229 chr12:38710491 ALG10B -0.52 -7.3 -0.37 2e-12 Heart rate; LIHC cis rs6840360 0.571 rs62327272 chr4:152545090 A/C cg22705602 chr4:152727874 NA -0.34 -6.49 -0.33 3.08e-10 Intelligence (multi-trait analysis); LIHC cis rs10927875 0.526 rs2179615 chr1:16282426 G/A cg21385522 chr1:16154831 NA -1.08 -11.28 -0.52 2.6e-25 Dilated cardiomyopathy; LIHC cis rs1552244 0.882 rs3755782 chr3:10029305 T/C cg08888203 chr3:10149979 C3orf24 0.47 6.15 0.32 2.13e-9 Alzheimer's disease; LIHC cis rs7100689 0.784 rs11202699 chr10:82131453 A/G cg01528321 chr10:82214614 TSPAN14 0.87 11.84 0.54 2.43e-27 Post bronchodilator FEV1; LIHC cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg22963979 chr7:1858916 MAD1L1 0.42 6.71 0.34 7.87e-11 Bipolar disorder and schizophrenia; LIHC cis rs7129556 0.520 rs6592737 chr11:77322619 A/T cg21573582 chr11:77300763 AQP11 0.38 5.72 0.3 2.27e-8 Weight loss (gastric bypass surgery); LIHC cis rs4555082 0.834 rs4412909 chr14:105759226 T/C cg13114125 chr14:105738426 BRF1 -0.74 -9.6 -0.46 1.74e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs3784262 1.000 rs7165247 chr15:58251786 C/T cg12031962 chr15:58353849 ALDH1A2 0.32 6.49 0.33 2.98e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7487075 0.619 rs4768710 chr12:46808104 G/A cg23829395 chr12:46796953 NA 0.35 6.26 0.32 1.16e-9 Itch intensity from mosquito bite; LIHC cis rs2120019 1.000 rs2083731 chr15:75368538 A/C cg06012730 chr15:75315579 PPCDC -0.32 -5.91 -0.3 8.11e-9 Blood trace element (Zn levels); LIHC cis rs2404602 0.583 rs2469542 chr15:76557476 A/G cg23625390 chr15:77176239 SCAPER -0.35 -6.06 -0.31 3.54e-9 Blood metabolite levels; LIHC trans rs2727020 0.521 rs7114564 chr11:49571231 C/T cg03929089 chr4:120376271 NA 0.71 10.26 0.49 1.01e-21 Coronary artery disease; LIHC cis rs898097 0.578 rs8069697 chr17:80908110 T/C cg15664640 chr17:80829946 TBCD 0.45 7.4 0.37 1.04e-12 Breast cancer; LIHC cis rs7927771 0.839 rs11039308 chr11:47622412 G/A cg20135002 chr11:47629003 NA -0.52 -9.14 -0.44 5.78e-18 Subjective well-being; LIHC cis rs57920188 0.513 rs4290031 chr1:4094701 A/G cg20703997 chr1:4087676 NA 0.49 6.1 0.31 2.87e-9 Interleukin-17 levels; LIHC cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC trans rs561341 0.843 rs56389115 chr17:30237308 T/C cg20587970 chr11:113659929 NA -0.61 -7.23 -0.36 3.15e-12 Hip circumference adjusted for BMI; LIHC cis rs7246657 0.943 rs7257672 chr19:37823859 G/C cg23950597 chr19:37808831 NA -0.44 -5.94 -0.31 6.86e-9 Coronary artery calcification; LIHC cis rs2361718 0.564 rs2304844 chr17:78084507 G/C cg09238746 chr17:78121135 EIF4A3 -0.68 -10.44 -0.49 2.54e-22 Yeast infection; LIHC cis rs6860806 0.507 rs270606 chr5:131650867 A/G cg24060327 chr5:131705240 SLC22A5 -0.82 -12.73 -0.57 1.23e-30 Breast cancer; LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.28 0.41 2.88e-15 Height; LIHC cis rs12286929 0.644 rs9645660 chr11:115081563 C/T cg04055981 chr11:115044050 NA 0.49 7.61 0.38 2.65e-13 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1577917 1.000 rs7771342 chr6:86631936 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC cis rs801193 1.000 rs4279493 chr7:66226620 C/T cg18876405 chr7:65276391 NA 0.42 7.35 0.37 1.52e-12 Aortic root size; LIHC cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg10295955 chr4:187884368 NA -0.96 -22.55 -0.77 1.2e-69 Lobe attachment (rater-scored or self-reported); LIHC cis rs4638749 0.677 rs6741222 chr2:108841082 A/G cg06795125 chr2:108905320 SULT1C2 -0.3 -5.96 -0.31 6.23e-9 Blood pressure; LIHC cis rs1552244 0.608 rs9837460 chr3:10049922 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -7.97 -0.4 2.43e-14 Alzheimer's disease; LIHC trans rs3749237 0.964 rs34522271 chr3:49808517 A/G cg21659725 chr3:3221576 CRBN 0.8 12.22 0.55 1e-28 Resting heart rate; LIHC cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.84e-10 Diabetic kidney disease; LIHC cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg11062466 chr8:58055876 NA 0.39 5.73 0.3 2.23e-8 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.797 rs798497 chr7:2795957 A/G cg13628971 chr7:2884303 GNA12 0.54 7.97 0.4 2.45e-14 Height; LIHC cis rs2361718 0.501 rs11869566 chr17:78143248 T/C cg09238746 chr17:78121135 EIF4A3 -0.75 -11.89 -0.54 1.57e-27 Yeast infection; LIHC cis rs9902453 0.730 rs4583306 chr17:28538715 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.5 -7.33 -0.37 1.71e-12 Coffee consumption (cups per day); LIHC cis rs12477438 0.798 rs2123686 chr2:99690135 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.37 -0.41 1.51e-15 Chronic sinus infection; LIHC cis rs4862750 0.914 rs1991256 chr4:187875330 A/G cg10295955 chr4:187884368 NA -0.95 -20.93 -0.75 3.29e-63 Lobe attachment (rater-scored or self-reported); LIHC cis rs7927592 0.763 rs3740628 chr11:68381415 A/G cg16797656 chr11:68205561 LRP5 0.5 8.79 0.43 7.66e-17 Total body bone mineral density; LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.67 9.44 0.45 5.93e-19 Lymphocyte counts; LIHC cis rs7191439 0.858 rs7205626 chr16:88780472 T/C cg27087555 chr16:88793112 FAM38A -1.33 -12.63 -0.56 2.91e-30 Plateletcrit; LIHC cis rs12464559 0.649 rs4664496 chr2:152522556 T/C cg01189475 chr2:152685088 ARL5A -0.7 -9.18 -0.44 4.21e-18 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs11864453 0.826 rs2072142 chr16:72132713 C/T cg01557791 chr16:72042693 DHODH -0.53 -8.56 -0.42 4.01e-16 Fibrinogen levels; LIHC cis rs7520050 0.931 rs6688365 chr1:46329884 G/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs12995491 0.731 rs34991383 chr2:88500337 T/G cg07952391 chr2:88470173 THNSL2 -0.41 -5.72 -0.3 2.29e-8 Response to metformin (IC50); LIHC cis rs4453791 0.932 rs78329075 chr3:38868431 C/T cg02254461 chr3:39195904 CSRNP1 0.66 5.83 0.3 1.26e-8 Social communication problems; LIHC cis rs7592578 0.640 rs56127319 chr2:191296429 G/A cg27211696 chr2:191398769 TMEM194B -0.49 -6.45 -0.33 3.85e-10 Diastolic blood pressure; LIHC cis rs6815814 0.731 rs4504266 chr4:38773754 G/A cg06935464 chr4:38784597 TLR10 0.38 5.96 0.31 6.18e-9 Breast cancer; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg02475777 chr4:1388615 CRIPAK 0.57 8.61 0.42 2.64e-16 Longevity; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07348706 chr3:112709771 GTPBP8 0.43 6.2 0.32 1.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6582630 0.555 rs10880624 chr12:38526316 C/T cg26384229 chr12:38710491 ALG10B 0.69 9.72 0.47 6.83e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs60871478 1.000 rs6460801 chr7:810506 T/C cg05535760 chr7:792225 HEATR2 0.8 11.36 0.52 1.4e-25 Cerebrospinal P-tau181p levels; LIHC cis rs921968 0.608 rs678814 chr2:219359287 T/C cg17980119 chr2:219472607 PLCD4 0.36 6.21 0.32 1.55e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs769267 0.930 rs1063966 chr19:19616742 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.5 7.6 0.38 2.93e-13 Tonsillectomy; LIHC cis rs240764 0.631 rs9322174 chr6:101204193 G/C cg09795085 chr6:101329169 ASCC3 -0.41 -6.05 -0.31 3.82e-9 Neuroticism; LIHC trans rs983392 0.709 rs11601689 chr11:59996266 G/C cg17275991 chr19:58003312 ZNF419 0.43 6.16 0.32 2.06e-9 Alzheimer's disease (late onset); LIHC trans rs916888 0.773 rs169201 chr17:44790203 A/G cg12297030 chr17:43662878 NA -0.64 -6.09 -0.31 2.98e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2304069 0.695 rs6866298 chr5:149439588 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.84 10.77 0.5 1.71e-23 HIV-1 control; LIHC cis rs4665809 0.618 rs7579199 chr2:26266496 G/A cg27170947 chr2:26402098 FAM59B -0.69 -8.58 -0.42 3.32e-16 Gut microbiome composition (summer); LIHC cis rs12744310 0.832 rs12027990 chr1:41764437 T/C cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs10411161 1.000 rs10412080 chr19:52373508 A/C cg22319618 chr22:45562946 NUP50 -0.54 -7.31 -0.37 1.93e-12 Breast cancer; LIHC cis rs2153535 0.580 rs2184584 chr6:8468407 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7107174 1.000 rs2510037 chr11:77966099 A/G cg02023728 chr11:77925099 USP35 0.45 8.57 0.42 3.63e-16 Testicular germ cell tumor; LIHC trans rs1005277 0.541 rs1740741 chr10:38515334 C/T cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg18306943 chr3:40428807 ENTPD3 -0.35 -6.01 -0.31 4.82e-9 Renal cell carcinoma; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg27411370 chr8:25316735 KCTD9;CDCA2 0.48 6.3 0.32 9.26e-10 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs9611565 0.512 rs139566 chr22:42199277 A/G cg06481639 chr22:41940642 POLR3H -0.61 -5.83 -0.3 1.27e-8 Vitiligo; LIHC cis rs9790314 1.000 rs62279921 chr3:161065441 T/C cg04691961 chr3:161091175 C3orf57 -0.41 -6.53 -0.33 2.37e-10 Morning vs. evening chronotype; LIHC cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg18876405 chr7:65276391 NA 0.56 9.39 0.45 9.02e-19 Aortic root size; LIHC cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.47 6.46 0.33 3.57e-10 Bipolar disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04132851 chr1:85155548 SSX2IP 0.49 7.46 0.37 7.33e-13 Cognitive function; LIHC cis rs6582630 0.537 rs7310749 chr12:38400472 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.28 0.41 2.72e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs1707322 0.752 rs6678444 chr1:46229847 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.21 0.36 3.7e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3849570 0.925 rs6765917 chr3:81891116 C/T cg07356753 chr3:81810745 GBE1 -0.54 -8.56 -0.42 3.82e-16 Waist circumference;Body mass index; LIHC cis rs7107174 0.901 rs2450133 chr11:77925759 A/C cg02023728 chr11:77925099 USP35 0.52 9.75 0.47 5.65e-20 Testicular germ cell tumor; LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC cis rs10949834 0.824 rs2285026 chr7:73530404 C/T cg07137043 chr7:73588983 EIF4H -0.6 -6.01 -0.31 4.74e-9 Verbal memory performance (residualized delayed recall change); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26940751 chr1:143467856 NA -0.39 -7.64 -0.38 2.24e-13 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs875971 0.862 rs7796162 chr7:65745758 T/C cg11764359 chr7:65958608 NA -0.78 -13.49 -0.59 1.5e-33 Aortic root size; LIHC cis rs9916302 0.861 rs632202 chr17:37453294 C/A cg07936489 chr17:37558343 FBXL20 0.84 13.64 0.59 4e-34 Glomerular filtration rate (creatinine); LIHC cis rs7095944 0.613 rs11245366 chr10:126482849 C/T cg08799069 chr10:126477246 METTL10 -0.4 -7.28 -0.37 2.37e-12 Asthma; LIHC cis rs7312774 0.618 rs7968263 chr12:107330844 C/A cg16260113 chr12:107380972 MTERFD3 0.85 11.02 0.51 2.3e-24 Severe influenza A (H1N1) infection; LIHC cis rs965469 1.000 rs1331215 chr20:3376565 T/C cg25506879 chr20:3388711 C20orf194 -0.56 -6.7 -0.34 8.8e-11 IFN-related cytopenia; LIHC cis rs7249142 0.597 rs759999 chr19:19281207 A/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.46 -7.55 -0.38 3.89e-13 IgG glycosylation; LIHC cis rs11190604 1.000 rs3793706 chr10:102269085 A/C cg07080220 chr10:102295463 HIF1AN -0.55 -8.12 -0.4 8.55e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2991971 0.901 rs11211122 chr1:45954650 C/T cg24296786 chr1:45957014 TESK2 0.58 9.3 0.45 1.77e-18 High light scatter reticulocyte count; LIHC cis rs2742417 0.603 rs2742372 chr3:45783472 T/C cg04837898 chr3:45731254 SACM1L -0.51 -8.61 -0.42 2.64e-16 Response to anti-depressant treatment in major depressive disorder; LIHC trans rs1005277 0.505 rs10827835 chr10:38150709 G/A cg27523141 chr10:43048294 ZNF37B -0.39 -6.73 -0.34 7.11e-11 Extrinsic epigenetic age acceleration; LIHC cis rs7107174 1.000 rs2512542 chr11:77981780 G/A cg02023728 chr11:77925099 USP35 0.45 8.65 0.42 2.07e-16 Testicular germ cell tumor; LIHC trans rs7142002 1.000 rs7145448 chr14:102361064 A/C cg18984499 chr17:8286166 RPL26 0.65 6.19 0.32 1.77e-9 Autism; LIHC cis rs4925386 0.840 rs6142738 chr20:60919960 C/T cg06026331 chr20:60912101 LAMA5 -0.63 -9.4 -0.45 8.02e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg08859206 chr1:53392774 SCP2 0.46 7.35 0.37 1.47e-12 Monocyte count; LIHC cis rs1003719 0.591 rs9636914 chr21:38589732 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.56 7.13 0.36 6.05e-12 Eye color traits; LIHC trans rs1973993 0.689 rs17115225 chr1:96884330 C/T cg10631902 chr5:14652156 NA -0.3 -6.42 -0.33 4.43e-10 Weight; LIHC cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg10295955 chr4:187884368 NA -0.96 -21.11 -0.75 6.53e-64 Lobe attachment (rater-scored or self-reported); LIHC cis rs10865541 0.902 rs33997548 chr2:3419366 A/G cg11642891 chr2:3452563 TTC15 -0.45 -7.2 -0.36 3.8e-12 Obesity-related traits; LIHC cis rs6750047 0.868 rs1431332 chr2:38280253 G/A cg07380506 chr2:38303506 CYP1B1 0.56 6.92 0.35 2.23e-11 Cutaneous malignant melanoma;Melanoma; LIHC cis rs2204008 0.547 rs12318267 chr12:38250905 T/G cg26384229 chr12:38710491 ALG10B -0.44 -5.77 -0.3 1.78e-8 Bladder cancer; LIHC cis rs2637266 0.935 rs7477361 chr10:78393586 G/A cg18941641 chr10:78392320 NA 0.29 6.39 0.33 5.33e-10 Pulmonary function; LIHC cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 6.02e-12 Diabetic kidney disease; LIHC cis rs722599 0.748 rs731952 chr14:75366447 A/G cg11812906 chr14:75593930 NEK9 0.4 6.52 0.33 2.56e-10 IgG glycosylation; LIHC cis rs965469 0.817 rs16988490 chr20:3335431 C/T cg25506879 chr20:3388711 C20orf194 0.52 6.09 0.31 3.07e-9 IFN-related cytopenia; LIHC cis rs965469 0.779 rs2207994 chr20:3294304 C/T cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs240764 0.782 rs239223 chr6:101112345 A/G cg09795085 chr6:101329169 ASCC3 0.52 7.4 0.37 1.06e-12 Neuroticism; LIHC cis rs4253772 0.591 rs9627324 chr22:46656511 A/G cg24881330 chr22:46731750 TRMU 0.54 5.82 0.3 1.39e-8 LDL cholesterol;Cholesterol, total; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg24846343 chr22:24311635 DDTL 0.67 13.47 0.59 1.87e-33 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs55665837 0.701 rs2007361 chr11:14662722 A/G cg19336497 chr11:14380999 RRAS2 -0.37 -6.07 -0.31 3.4e-9 Vitamin D levels; LIHC cis rs7474896 0.515 rs624359 chr10:38299132 T/C cg25427524 chr10:38739819 LOC399744 0.45 5.9 0.3 8.53e-9 Obesity (extreme); LIHC cis rs3617 0.625 rs6445541 chr3:52880128 G/T cg11645453 chr3:52864694 ITIH4 0.22 5.76 0.3 1.91e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs6964587 1.000 rs12540565 chr7:91633213 T/G cg17063962 chr7:91808500 NA 1.03 19.85 0.73 6.84e-59 Breast cancer; LIHC cis rs798554 0.616 rs1636251 chr7:2884720 T/C cg13628971 chr7:2884303 GNA12 0.48 8.44 0.42 9.06e-16 Height; LIHC cis rs9457247 1.000 rs422094 chr6:167397033 C/G cg12798992 chr6:167411361 FGFR1OP 0.59 9.84 0.47 2.7e-20 Crohn's disease; LIHC trans rs1973993 0.691 rs6658131 chr1:96889314 C/T cg10631902 chr5:14652156 NA 0.36 9.83 0.47 3.06e-20 Weight; LIHC cis rs875971 0.638 rs10278816 chr7:66036987 T/C cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC trans rs2727020 1.000 rs2727020 chr11:49111407 C/G cg15704280 chr7:45808275 SEPT13 0.72 10.29 0.49 7.88e-22 Coronary artery disease; LIHC cis rs7223966 1.000 rs2854223 chr17:61939014 A/G cg05941027 chr17:61774174 LIMD2 0.32 6.74 0.34 6.7e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6933660 0.760 rs1825368 chr6:151775259 C/A cg10883421 chr6:151773342 RMND1;C6orf211 0.63 10.37 0.49 4.49e-22 Menarche (age at onset); LIHC cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.07 -0.44 9.45e-18 Bipolar disorder; LIHC cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg08392591 chr16:89556376 ANKRD11 0.41 6.14 0.32 2.31e-9 Multiple myeloma (IgH translocation); LIHC cis rs7131987 0.650 rs7311912 chr12:29475703 G/C cg16970926 chr12:29381810 FAR2 0.28 5.97 0.31 6.02e-9 QT interval; LIHC cis rs8062405 1.000 rs72793812 chr16:28840381 A/G cg07451762 chr16:28383216 NA 0.34 6.32 0.32 8.09e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4253772 0.591 rs6007740 chr22:46654323 A/G cg09491104 chr22:46646882 C22orf40 0.66 7.74 0.39 1.1e-13 LDL cholesterol;Cholesterol, total; LIHC cis rs2067615 0.524 rs10778504 chr12:107120424 C/T cg15890332 chr12:107067104 RFX4 0.26 6.11 0.31 2.76e-9 Heart rate; LIHC trans rs8108034 0.920 rs30480 chr19:39807213 A/G cg03482411 chr20:62572509 UCKL1 -0.56 -6.09 -0.31 3.02e-9 Lung adenocarcinoma; LIHC cis rs921968 0.519 rs62191659 chr2:219630510 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7903847 0.642 rs7092499 chr10:99140313 A/G cg06359132 chr10:99160096 RRP12 -0.41 -6.44 -0.33 4.15e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12579753 1.000 rs17749267 chr12:82178308 A/G cg07988820 chr12:82153109 PPFIA2 0.44 5.81 0.3 1.45e-8 Resting heart rate; LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg14709524 chr16:89940631 TCF25 0.55 7.23 0.36 3.15e-12 Skin colour saturation; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg07677032 chr17:61819896 STRADA 0.42 6.15 0.32 2.12e-9 Prudent dietary pattern; LIHC cis rs9309473 1.000 rs10179134 chr2:73637519 A/G cg20560298 chr2:73613845 ALMS1 -0.57 -6.49 -0.33 3.02e-10 Metabolite levels; LIHC cis rs7027203 0.828 rs4744287 chr9:96585567 A/G cg13679303 chr9:96623674 NA 0.3 6.72 0.34 7.57e-11 DNA methylation (variation); LIHC cis rs4332037 0.762 rs11770612 chr7:1915493 A/C cg23043544 chr7:2124092 MAD1L1 -0.42 -6.3 -0.32 9.09e-10 Bipolar disorder; LIHC cis rs796364 0.806 rs78037592 chr2:201105734 G/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -7.09 -0.36 7.72e-12 Schizophrenia; LIHC cis rs568617 0.716 rs77779142 chr11:65599656 C/T cg04055107 chr11:65626734 MUS81;CFL1 0.57 6.92 0.35 2.27e-11 Crohn's disease; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg18202627 chr2:200776533 C2orf69 0.4 6.13 0.31 2.44e-9 Metabolic traits; LIHC cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg20887711 chr4:1340912 KIAA1530 0.48 7.04 0.36 1.04e-11 Longevity; LIHC cis rs74233809 1.000 rs79082900 chr10:104877302 T/C cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.43e-9 Birth weight; LIHC cis rs6733011 0.578 rs4851171 chr2:99510817 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.45 -6.44 -0.33 3.95e-10 Bipolar disorder; LIHC cis rs6450176 1.000 rs7735253 chr5:53297611 G/A ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs7447593 0.518 rs4074995 chr5:176797343 C/T cg17509989 chr5:176798049 RGS14 0.85 12.96 0.57 1.54e-31 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs2361718 0.967 rs2361719 chr17:78103403 A/G cg06718696 chr17:78121285 EIF4A3 -0.42 -5.74 -0.3 2.09e-8 Yeast infection; LIHC cis rs3780378 1.000 rs1328918 chr9:5107394 A/G cg02405213 chr9:5042618 JAK2 -0.46 -7.84 -0.39 5.96e-14 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg03264133 chr6:25882463 NA 0.51 6.33 0.32 7.82e-10 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.05e-17 Bipolar disorder; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11473911 chr4:140005743 ELF2 0.44 6.22 0.32 1.41e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg09222892 chr1:25734099 RHCE -0.47 -8.78 -0.43 7.69e-17 Erythrocyte sedimentation rate; LIHC cis rs11625487 0.957 rs10145540 chr14:77957354 C/T cg20045696 chr14:77926864 AHSA1 -0.71 -7.3 -0.37 1.98e-12 Neutrophil percentage of white cells;Sum neutrophil eosinophil counts;Neutrophil count; LIHC cis rs2576037 0.526 rs509647 chr18:44383675 G/T cg19077165 chr18:44547161 KATNAL2 -0.43 -6.57 -0.33 1.84e-10 Personality dimensions; LIHC cis rs743757 0.816 rs6792502 chr3:50531201 C/A cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.07 0.36 8.63e-12 Diastolic blood pressure; LIHC cis rs4319547 0.741 rs4758663 chr12:122939483 A/G cg23029597 chr12:123009494 RSRC2 -0.47 -6.74 -0.34 6.86e-11 Body mass index; LIHC cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg11062466 chr8:58055876 NA 0.51 7.09 0.36 7.72e-12 Developmental language disorder (linguistic errors); LIHC trans rs1704198 1.000 rs830335 chr1:213898743 G/T cg02442787 chr4:139230014 NA 0.4 6.16 0.32 2.02e-9 Obesity; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg11235426 chr6:292522 DUSP22 -0.53 -7.09 -0.36 7.64e-12 Menopause (age at onset); LIHC trans rs7677751 0.806 rs6554163 chr4:55102559 A/T cg17183009 chr3:120277827 NA 0.52 6.31 0.32 8.5e-10 Corneal astigmatism; LIHC cis rs477692 0.569 rs10764882 chr10:131306496 C/G cg05714579 chr10:131428358 MGMT 0.4 6.47 0.33 3.47e-10 Response to temozolomide; LIHC cis rs7252981 0.632 rs739461 chr19:19715794 T/C cg21559469 chr19:19431446 KIAA0892;SF4 -0.45 -5.73 -0.3 2.2e-8 Perceived unattractiveness to mosquitoes; LIHC cis rs55702914 0.746 rs7588530 chr2:198146698 A/C cg03934865 chr2:198174659 NA -0.4 -5.71 -0.3 2.42e-8 Major depression and alcohol dependence; LIHC cis rs7100689 0.646 rs7089003 chr10:82124155 T/C cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs9649213 0.574 rs62478236 chr7:98030377 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.39 -6.08 -0.31 3.25e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs6598955 0.671 rs11247914 chr1:26648838 G/T cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.29 -0.41 2.71e-15 Obesity-related traits; LIHC cis rs9911578 1.000 rs11079365 chr17:56945430 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs2576037 0.583 rs501882 chr18:44411066 A/T cg19077165 chr18:44547161 KATNAL2 -0.47 -6.81 -0.35 4.41e-11 Personality dimensions; LIHC cis rs9818758 0.607 rs9880088 chr3:49178990 G/A cg07636037 chr3:49044803 WDR6 -0.79 -8.36 -0.41 1.6e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs589448 0.538 rs622656 chr12:69753595 C/T cg22834771 chr12:69754056 YEATS4 -0.46 -7.81 -0.39 7.28e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs4407350 0.837 rs5765710 chr22:44914354 C/T cg04154583 chr22:44889756 LDOC1L -0.29 -5.78 -0.3 1.64e-8 Intelligence (multi-trait analysis); LIHC cis rs9503598 0.543 rs913536 chr6:3432608 G/A cg00476032 chr6:3446245 SLC22A23 -0.33 -6.0 -0.31 4.96e-9 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg09033563 chr22:24373618 LOC391322 -0.46 -6.25 -0.32 1.25e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs57590327 0.503 rs9852235 chr3:81508355 A/G cg07356753 chr3:81810745 GBE1 0.46 6.85 0.35 3.4e-11 Extraversion; LIHC cis rs798766 0.904 rs13142863 chr4:1755549 T/G cg21231739 chr4:1642635 FAM53A -0.37 -5.81 -0.3 1.41e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs67311347 1.000 rs34762643 chr3:40475433 C/T cg09455208 chr3:40491958 NA 0.36 7.4 0.37 1.09e-12 Renal cell carcinoma; LIHC cis rs1555399 0.868 rs7160654 chr14:67983491 C/T cg16224230 chr14:67978224 TMEM229B -0.25 -6.04 -0.31 4.02e-9 Parkinson's disease; LIHC cis rs17685 0.743 rs10277259 chr7:75802674 A/C cg01364799 chr7:75623366 TMEM120A -0.52 -7.73 -0.39 1.19e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2842992 0.789 rs4709376 chr6:160226337 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.97 0.44 1.99e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs7617773 0.817 rs35456569 chr3:48250899 T/A cg11946769 chr3:48343235 NME6 0.89 11.14 0.52 8.2e-25 Coronary artery disease; LIHC cis rs561341 0.629 rs7216107 chr17:30224419 G/A cg13647721 chr17:30228624 UTP6 0.73 8.36 0.41 1.59e-15 Hip circumference adjusted for BMI; LIHC cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1814175 0.817 rs4881627 chr11:49953955 C/A cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs1113500 0.933 rs10881500 chr1:108638895 C/T cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.88e-12 Growth-regulated protein alpha levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07077115 chr13:28024429 MTIF3 0.48 7.42 0.37 9.32e-13 Cognitive function; LIHC cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg18252515 chr7:66147081 NA 1.29 17.34 0.68 9.06e-49 Diabetic kidney disease; LIHC cis rs9318086 0.687 rs9507182 chr13:24442365 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.58 11.51 0.53 3.98e-26 Myopia (pathological); LIHC cis rs559928 0.606 rs57021319 chr11:63956102 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 7.63 0.38 2.3e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs611744 0.573 rs674580 chr8:109251690 C/G cg21045802 chr8:109455806 TTC35 0.63 11.24 0.52 3.83e-25 Dupuytren's disease; LIHC cis rs739401 0.572 rs739399 chr11:3016452 A/G cg25174290 chr11:3078921 CARS 0.58 9.06 0.44 1.02e-17 Longevity; LIHC cis rs6840360 0.967 rs6841204 chr4:152598603 C/T cg22705602 chr4:152727874 NA -0.31 -6.58 -0.34 1.8e-10 Intelligence (multi-trait analysis); LIHC cis rs11676348 0.791 rs4133195 chr2:218951245 A/G cg00012203 chr2:219082015 ARPC2 0.54 7.68 0.38 1.74e-13 Ulcerative colitis; LIHC cis rs7264396 0.635 rs6058355 chr20:34491343 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.5 -0.49 1.57e-22 Total cholesterol levels; LIHC cis rs9457247 0.663 rs9459839 chr6:167431829 T/C cg12798992 chr6:167411361 FGFR1OP 0.45 7.25 0.36 2.86e-12 Crohn's disease; LIHC cis rs11792861 0.962 rs72607161 chr9:111792640 T/C cg13535736 chr9:111863775 C9orf5 -0.42 -6.42 -0.33 4.67e-10 Menarche (age at onset); LIHC cis rs904251 0.504 rs9380677 chr6:37480366 A/G cg08126542 chr6:37504118 NA -0.37 -6.33 -0.32 7.52e-10 Cognitive performance; LIHC cis rs4319547 0.695 rs11057797 chr12:122860732 G/A cg05707623 chr12:122985044 ZCCHC8 0.55 7.22 0.36 3.47e-12 Body mass index; LIHC cis rs9399135 0.636 rs4646871 chr6:135265617 A/G cg22676075 chr6:135203613 NA -0.4 -6.46 -0.33 3.69e-10 Red blood cell count; LIHC cis rs7927771 0.826 rs7925389 chr11:47466790 A/T cg20135002 chr11:47629003 NA -0.54 -9.14 -0.44 5.58e-18 Subjective well-being; LIHC cis rs2806561 0.704 rs664301 chr1:23522522 C/T cg12483005 chr1:23474871 LUZP1 0.47 7.24 0.36 3.01e-12 Height; LIHC cis rs6466055 0.777 rs3801285 chr7:104837801 C/A cg04380332 chr7:105027541 SRPK2 -0.36 -6.73 -0.34 7.2e-11 Schizophrenia; LIHC cis rs4450131 0.522 rs17152232 chr10:126398927 A/G cg20435097 chr10:126320824 FAM53B 0.65 11.79 0.54 3.88e-27 White blood cell count (basophil); LIHC cis rs739401 0.582 rs7932369 chr11:2958468 A/G cg25174290 chr11:3078921 CARS -0.57 -8.56 -0.42 3.78e-16 Longevity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23837253 chr19:47759802 CCDC9 0.48 6.97 0.35 1.65e-11 Lung function (FEV1/FVC); LIHC cis rs4906332 1.000 rs11625172 chr14:103944912 G/A cg19000871 chr14:103996768 TRMT61A -0.47 -7.98 -0.4 2.26e-14 Coronary artery disease; LIHC cis rs1348850 0.914 rs10170667 chr2:178336878 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.9 14.29 0.61 1.24e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs912057 0.671 rs1294433 chr6:6745163 G/A cg06612196 chr6:6737390 NA 0.51 9.55 0.46 2.68e-19 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs1046896 0.628 rs12452314 chr17:80723362 A/G cg19500275 chr17:80737654 TBCD 0.49 7.03 0.36 1.14e-11 Glycated hemoglobin levels; LIHC cis rs2439831 0.867 rs11856184 chr15:43919162 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.87 0.35 3.04e-11 Lung cancer in ever smokers; LIHC cis rs17685 0.753 rs1637044 chr7:75703744 T/C cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6456156 0.692 rs9457270 chr6:167512928 A/G cg12798992 chr6:167411361 FGFR1OP 0.39 5.9 0.3 8.66e-9 Primary biliary cholangitis; LIHC cis rs6952808 0.500 rs3778996 chr7:2177190 G/A cg21782813 chr7:2030301 MAD1L1 0.37 6.36 0.33 6.54e-10 Bipolar disorder and schizophrenia; LIHC cis rs4654899 0.965 rs6692081 chr1:21296363 T/C cg08539965 chr1:21396338 EIF4G3 0.34 5.96 0.31 6.37e-9 Superior frontal gyrus grey matter volume; LIHC cis rs73001065 0.636 rs28720066 chr19:19572220 G/T cg03709012 chr19:19516395 GATAD2A 0.95 10.48 0.49 1.75e-22 LDL cholesterol; LIHC trans rs6934970 1.000 rs7745564 chr6:113101580 G/A cg09308777 chr6:169852575 NA 0.59 6.29 0.32 9.63e-10 Bipolar disorder (body mass index interaction); LIHC cis rs55823223 0.564 rs4572466 chr17:73846314 A/C cg10935138 chr17:73851978 WBP2 0.69 9.24 0.45 2.67e-18 Psoriasis; LIHC cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg27297192 chr10:134578999 INPP5A 0.52 7.07 0.36 8.91e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7607369 0.648 rs7582193 chr2:219652532 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -5.92 -0.3 8.01e-9 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs4969178 0.965 rs8075131 chr17:76394595 T/G cg20026190 chr17:76395443 PGS1 0.45 7.15 0.36 5.19e-12 HDL cholesterol levels; LIHC cis rs4845570 1.000 rs7542898 chr1:151753622 T/G cg07092448 chr1:151763213 TDRKH -0.72 -7.9 -0.39 3.75e-14 Coronary artery disease; LIHC trans rs1005277 0.505 rs200939 chr10:38139483 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.47 -0.33 3.34e-10 Extrinsic epigenetic age acceleration; LIHC cis rs17001868 0.614 rs61467436 chr22:40736713 T/C cg07138101 chr22:40742427 ADSL 0.54 6.4 0.33 5.03e-10 Mammographic density (dense area); LIHC cis rs826838 0.616 rs2387921 chr12:38624767 T/C cg26384229 chr12:38710491 ALG10B -0.51 -7.08 -0.36 8.34e-12 Heart rate; LIHC cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg23758822 chr17:41437982 NA 0.91 16.88 0.67 6.34e-47 Menopause (age at onset); LIHC cis rs1005277 0.505 rs13503 chr10:38239843 C/A cg25427524 chr10:38739819 LOC399744 0.65 12.71 0.57 1.41e-30 Extrinsic epigenetic age acceleration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23477849 chr19:5698492 LONP1 -0.45 -6.77 -0.34 5.55e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7598759 0.548 rs1823328 chr2:232355184 G/A cg19187155 chr2:232395269 NMUR1 0.58 8.74 0.43 1.05e-16 Noise-induced hearing loss; LIHC cis rs11031096 0.782 rs2284450 chr11:4149214 A/T cg18678763 chr11:4115507 RRM1 -0.57 -8.62 -0.42 2.49e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs986417 0.901 rs1955690 chr14:61000492 A/G cg27398547 chr14:60952738 C14orf39 -0.83 -9.59 -0.46 1.88e-19 Gut microbiota (bacterial taxa); LIHC cis rs6450176 0.904 rs4351101 chr5:53300591 G/A ch.5.1024479R chr5:53302184 ARL15 -0.81 -14.59 -0.62 8.14e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12463199 chr20:49126897 PTPN1 0.41 6.44 0.33 4.13e-10 Pancreatic cancer; LIHC cis rs3960554 0.660 rs55671363 chr7:75793405 T/C cg01364799 chr7:75623366 TMEM120A -0.54 -7.63 -0.38 2.41e-13 Eotaxin levels; LIHC cis rs2524276 1 rs2524276 chr6:31408265 C/A cg12985770 chr6:31324627 HLA-B 0.79 6.09 0.31 3.01e-9 Capecitabine sensitivity; LIHC cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg06481639 chr22:41940642 POLR3H 0.62 5.86 0.3 1.1e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg09417038 chr21:47716443 C21orf57 -0.46 -7.05 -0.36 1.01e-11 Testicular germ cell tumor; LIHC cis rs8062405 0.755 rs12445823 chr16:28588049 A/C cg00204512 chr16:28754710 NA 0.4 6.95 0.35 1.83e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2050392 0.965 rs2265371 chr10:30690840 C/T cg25182066 chr10:30743637 MAP3K8 -0.44 -7.18 -0.36 4.26e-12 Inflammatory bowel disease; LIHC cis rs13394619 0.875 rs7576826 chr2:11723021 C/T cg07314298 chr2:11723111 GREB1 -0.5 -9.49 -0.46 3.98e-19 Endometriosis; LIHC cis rs9942416 0.660 rs41534344 chr5:74997832 T/C cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs1577917 0.666 rs6454471 chr6:86214456 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 12.01 0.54 5.85e-28 Response to antipsychotic treatment; LIHC cis rs9309711 0.544 rs9309712 chr2:3491327 G/T cg15541040 chr2:3486749 NA -0.39 -6.05 -0.31 3.8e-9 Neurofibrillary tangles; LIHC cis rs6500602 0.826 rs11076831 chr16:4460133 A/G cg08645402 chr16:4508243 NA -0.33 -5.74 -0.3 2.12e-8 Schizophrenia; LIHC cis rs2412488 0.927 rs2412447 chr4:54277516 C/T cg22241045 chr4:54363911 LNX1 -0.41 -6.71 -0.34 8.15e-11 DNA methylation (variation); LIHC cis rs9303401 0.659 rs16943326 chr17:57050365 C/T cg25039879 chr17:56429692 SUPT4H1 0.79 8.95 0.44 2.37e-17 Cognitive test performance; LIHC cis rs7927592 0.731 rs488381 chr11:68291693 G/A cg16797656 chr11:68205561 LRP5 -0.52 -9.24 -0.45 2.74e-18 Total body bone mineral density; LIHC cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg19539972 chr4:7069911 GRPEL1 0.68 9.89 0.47 1.82e-20 Monocyte percentage of white cells; LIHC trans rs4714291 0.963 rs847777 chr6:40055754 C/T cg02267698 chr19:7991119 CTXN1 0.38 6.15 0.32 2.17e-9 Strep throat; LIHC cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs722599 0.715 rs2300598 chr14:75359229 T/C cg11812906 chr14:75593930 NEK9 -0.46 -7.3 -0.37 1.97e-12 IgG glycosylation; LIHC cis rs875971 0.638 rs801216 chr7:66011667 T/C cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC cis rs1843834 0.611 rs1058360 chr2:225449242 A/T cg12698349 chr2:225449008 CUL3 0.66 10.1 0.48 3.73e-21 IgE levels in asthmatics (D.p. specific); LIHC cis rs72843506 0.722 rs74658636 chr17:20197982 A/G cg12065943 chr17:19881925 AKAP10 -0.36 -6.11 -0.31 2.75e-9 Schizophrenia; LIHC cis rs116095464 0.558 rs10077076 chr5:231940 C/T cg22857025 chr5:266934 NA -1.48 -17.96 -0.7 2.77e-51 Breast cancer; LIHC cis rs8027181 1.000 rs3850986 chr15:73091283 G/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.48 7.37 0.37 1.33e-12 Triglyceride levels; LIHC cis rs72653721 0.838 rs3798709 chr6:11001276 A/G cg13562911 chr6:11044106 ELOVL2 0.5 7.19 0.36 4.14e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs7961581 0.719 rs1705256 chr12:71601657 T/G cg05756094 chr12:71608604 NA 0.41 6.66 0.34 1.12e-10 Type 2 diabetes; LIHC cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg05368731 chr17:41323189 NBR1 0.73 12.49 0.56 9.12e-30 Menopause (age at onset); LIHC cis rs2000999 0.515 rs2854956 chr16:72115238 A/T cg16558253 chr16:72132732 DHX38 -0.5 -7.79 -0.39 7.91e-14 Total cholesterol levels;Cholesterol, total;Blood protein levels;LDL cholesterol levels;Haptoglobin levels;LDL cholesterol; LIHC cis rs4908768 0.501 rs6702060 chr1:8607024 G/A cg20416874 chr1:8611966 RERE -0.7 -15.08 -0.63 9.46e-40 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs892961 0.899 rs8071024 chr17:75414067 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.41 0.59 3.07e-33 Airflow obstruction; LIHC cis rs6088813 1.000 rs6142369 chr20:33973315 T/G cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC cis rs9911578 0.835 rs3744093 chr17:56492800 T/C cg05425664 chr17:57184151 TRIM37 0.56 7.97 0.4 2.45e-14 Intelligence (multi-trait analysis); LIHC cis rs9911578 1.000 rs7216680 chr17:56988243 G/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC trans rs75804782 0.520 rs72987319 chr2:239351143 C/T cg01134436 chr17:81009848 B3GNTL1 0.84 6.89 0.35 2.73e-11 Morning vs. evening chronotype;Chronotype; LIHC trans rs4906332 1.000 rs35862113 chr14:103857229 G/T cg17675199 chr6:35436792 RPL10A 0.32 6.32 0.32 8.08e-10 Coronary artery disease; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg23601095 chr6:26197514 HIST1H3D 0.53 5.74 0.3 2.1e-8 Gout;Renal underexcretion gout; LIHC cis rs1005277 0.683 rs7923868 chr10:37989766 T/C cg25427524 chr10:38739819 LOC399744 -0.57 -10.37 -0.49 4.25e-22 Extrinsic epigenetic age acceleration; LIHC cis rs9303401 0.614 rs56284918 chr17:57178838 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.9 0.54 1.54e-27 Cognitive test performance; LIHC cis rs6951245 0.554 rs11761322 chr7:1151657 A/G cg22907277 chr7:1156413 C7orf50 0.84 8.01 0.4 1.88e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg06873352 chr17:61820015 STRADA 0.75 13.58 0.59 6.97e-34 Prudent dietary pattern; LIHC cis rs597539 0.652 rs513615 chr11:68705504 G/T cg04772025 chr11:68637568 NA 0.5 6.32 0.32 8.13e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7772486 0.641 rs960385 chr6:146371074 G/A cg23711669 chr6:146136114 FBXO30 0.57 8.84 0.43 5.2e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs11166927 0.870 rs11166930 chr8:140824621 A/G cg16909799 chr8:140841666 TRAPPC9 -0.39 -6.5 -0.33 2.86e-10 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs12477438 0.520 rs6717723 chr2:99756930 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg14393609 chr7:65229607 NA 0.44 6.55 0.33 2.08e-10 Aortic root size; LIHC cis rs1008375 1.000 rs114490726 chr4:17680898 T/C cg02297831 chr4:17616191 MED28 0.41 6.58 0.34 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8114671 0.570 rs3761144 chr20:33544075 C/G cg07148914 chr20:33460835 GGT7 0.64 10.01 0.48 7.38e-21 Height; LIHC trans rs6600671 0.967 rs11249347 chr1:121188347 G/T cg09829573 chr1:144692074 NBPF9 -0.43 -7.83 -0.39 6.27e-14 Hip geometry; LIHC cis rs17228178 0.961 rs7172386 chr15:31467352 C/T cg01030201 chr15:31746330 NA -0.43 -5.92 -0.3 7.91e-9 Facial depth;Facial morphology (factor 1, breadth of lateral portion of upper face); LIHC trans rs17685 0.743 rs10277259 chr7:75802674 A/C cg19862616 chr7:65841803 NCRNA00174 0.94 19.24 0.72 2.06e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6088590 1.000 rs1998028 chr20:33344595 A/T cg06115741 chr20:33292138 TP53INP2 0.6 8.66 0.42 1.95e-16 Coronary artery disease; LIHC cis rs1059312 0.966 rs12370194 chr12:129277250 A/T cg09035930 chr12:129282057 SLC15A4 0.7 13.2 0.58 1.96e-32 Systemic lupus erythematosus; LIHC cis rs4638749 0.677 rs1563111 chr2:108845717 A/G cg25838818 chr2:108905173 SULT1C2 -0.39 -6.81 -0.35 4.37e-11 Blood pressure; LIHC cis rs9783347 0.961 rs4150588 chr11:18360131 G/A cg15585147 chr11:18324498 HPS5 0.42 6.7 0.34 8.6e-11 Pancreatic cancer; LIHC cis rs801193 0.967 rs34356500 chr7:66236607 G/T cg00343986 chr7:65444356 GUSB 0.42 6.29 0.32 9.6e-10 Aortic root size; LIHC cis rs11971779 0.680 rs11764236 chr7:139118514 C/T cg07862535 chr7:139043722 LUC7L2 0.63 10.91 0.51 5.59e-24 Diisocyanate-induced asthma; LIHC cis rs17685 0.753 rs55812043 chr7:75747241 T/C cg01364799 chr7:75623366 TMEM120A -0.48 -7.34 -0.37 1.59e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7520050 0.966 rs11810993 chr1:46478793 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.84 0.3 1.21e-8 Red blood cell count;Reticulocyte count; LIHC cis rs11098499 0.909 rs71614422 chr4:120359340 G/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs9660992 0.710 rs1180721 chr1:205232696 T/C cg21545522 chr1:205238299 TMCC2 0.39 7.62 0.38 2.54e-13 Mean corpuscular volume;Mean platelet volume; LIHC cis rs6960043 0.818 rs1558318 chr7:15065612 A/T cg19272540 chr7:15055459 NA -0.24 -6.63 -0.34 1.34e-10 Type 2 diabetes; LIHC cis rs1005277 0.579 rs2983343 chr10:38383332 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs7212590 0.748 rs73315252 chr17:57854855 A/G cg10252138 chr17:58120427 NA -0.61 -6.21 -0.32 1.5e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs78456975 1.000 rs11883965 chr2:1560062 T/C cg01028140 chr2:1542097 TPO -0.54 -6.44 -0.33 4.01e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1023500 0.505 rs134878 chr22:42663874 A/G cg04733989 chr22:42467013 NAGA 0.41 6.19 0.32 1.74e-9 Schizophrenia; LIHC cis rs6500596 0.506 rs1530088 chr16:4439131 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.44 5.76 0.3 1.87e-8 Schizophrenia; LIHC cis rs1664789 1.000 rs1664788 chr5:53282416 A/G ch.5.1024479R chr5:53302184 ARL15 0.53 8.56 0.42 3.76e-16 Waist circumference adjusted for body mass index; LIHC cis rs2404602 0.583 rs12913096 chr15:76551852 C/T cg22467129 chr15:76604101 ETFA -0.39 -6.51 -0.33 2.68e-10 Blood metabolite levels; LIHC cis rs523522 0.926 rs10774555 chr12:120971978 G/A cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14774288 chr8:30669556 PPP2CB -0.59 -7.15 -0.36 5.46e-12 Systolic blood pressure; LIHC cis rs1198430 1.000 rs1198434 chr1:23758134 A/G cg13183780 chr1:23809682 ASAP3 -0.56 -7.8 -0.39 7.68e-14 Total cholesterol levels; LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg13012494 chr21:47604986 C21orf56 -0.39 -6.03 -0.31 4.35e-9 Testicular germ cell tumor; LIHC cis rs2404602 0.608 rs12911035 chr15:76606591 T/C cg03037974 chr15:76606532 NA 0.91 23.48 0.79 2.82e-73 Blood metabolite levels; LIHC cis rs2153535 0.580 rs9505455 chr6:8478622 A/G cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs798554 1.000 rs798562 chr7:2757938 C/T cg19346786 chr7:2764209 NA -0.41 -5.98 -0.31 5.5e-9 Height; LIHC cis rs45535039 0.506 rs2511856 chr11:119144148 A/C cg16724696 chr11:118992527 HINFP -0.5 -6.53 -0.33 2.43e-10 Plateletcrit; LIHC cis rs7100689 0.646 rs1934694 chr10:82125325 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg14393609 chr7:65229607 NA -0.43 -6.45 -0.33 3.72e-10 Aortic root size; LIHC cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.71 0.3 2.46e-8 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg07677032 chr17:61819896 STRADA 0.43 6.19 0.32 1.75e-9 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg13047869 chr3:10149882 C3orf24 0.56 7.0 0.35 1.37e-11 Alzheimer's disease; LIHC cis rs599083 0.530 rs2472415 chr11:68185616 T/C cg01657329 chr11:68192670 LRP5 0.58 7.85 0.39 5.57e-14 Bone mineral density (spine); LIHC cis rs769267 0.896 rs10405625 chr19:19579046 T/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.95 0.31 6.6e-9 Tonsillectomy; LIHC cis rs9616064 0.812 rs5767288 chr22:46996254 G/A cg05621596 chr22:47072043 GRAMD4 -0.47 -6.47 -0.33 3.48e-10 Urate levels in obese individuals; LIHC cis rs8062405 1.000 rs55719896 chr16:28846866 G/A cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg00106254 chr7:1943704 MAD1L1 -0.47 -7.85 -0.39 5.42e-14 Bipolar disorder and schizophrenia; LIHC cis rs6061231 0.624 rs8668 chr20:60964064 C/T cg06026331 chr20:60912101 LAMA5 -0.39 -5.76 -0.3 1.85e-8 Colorectal cancer; LIHC cis rs807029 0.577 rs701835 chr10:102762127 A/G cg17130504 chr10:102756923 LZTS2 0.55 7.41 0.37 1.03e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.75 0.39 1.07e-13 Prudent dietary pattern; LIHC cis rs36051895 0.623 rs12351715 chr9:5262349 A/G cg02405213 chr9:5042618 JAK2 -0.61 -9.75 -0.47 5.76e-20 Pediatric autoimmune diseases; LIHC cis rs2108622 0.727 rs62107763 chr19:15982598 T/C cg13772218 chr19:15982569 NA 0.37 7.75 0.39 1.06e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs7208859 0.623 rs55814012 chr17:29077697 T/A cg14067834 chr17:29058358 SUZ12P 0.68 6.69 0.34 9.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11122272 0.735 rs2749709 chr1:231530476 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.56 -0.5 9.13e-23 Hemoglobin concentration; LIHC cis rs4268898 0.662 rs2303297 chr2:24432937 C/T cg06627628 chr2:24431161 ITSN2 -0.73 -9.61 -0.46 1.67e-19 Asthma; LIHC trans rs12620999 0.941 rs10803654 chr2:238036570 C/T cg15676719 chr1:167598521 RCSD1 -0.37 -6.65 -0.34 1.18e-10 Systemic lupus erythematosus; LIHC cis rs61990749 0.597 rs8003691 chr14:78211225 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.82 -0.39 6.67e-14 Fibroblast growth factor basic levels; LIHC cis rs11031096 0.502 rs7935824 chr11:4046900 C/G cg18678763 chr11:4115507 RRM1 -0.54 -8.19 -0.41 5.16e-15 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs17685 0.753 rs2286830 chr7:75693963 C/T cg04592579 chr7:75616294 TMEM120A -0.41 -7.1 -0.36 7.22e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs58235267 0.591 rs4671457 chr2:63346356 C/T cg17519650 chr2:63277830 OTX1 0.5 7.47 0.37 6.85e-13 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs12701220 0.894 rs12539012 chr7:1052133 G/A cg26769984 chr7:1090371 C7orf50 0.6 7.51 0.38 5.32e-13 Bronchopulmonary dysplasia; LIHC cis rs1816752 0.713 rs7336357 chr13:25017590 T/C cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.81e-10 Obesity-related traits; LIHC cis rs796364 0.806 rs78037592 chr2:201105734 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.8 -8.7 -0.43 1.43e-16 Schizophrenia; LIHC cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.35 0.45 1.17e-18 Bipolar disorder; LIHC cis rs2180341 0.814 rs6914131 chr6:127737489 T/C cg24812749 chr6:127587940 RNF146 0.8 12.66 0.56 2.11e-30 Breast cancer; LIHC trans rs459571 0.715 rs401826 chr9:136890591 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.61 -9.6 -0.46 1.77e-19 Platelet distribution width; LIHC cis rs11671005 0.735 rs3826684 chr19:58918705 T/C cg25952890 chr19:58913133 NA 0.69 7.4 0.37 1.07e-12 Mean platelet volume; LIHC cis rs11122272 0.766 rs1435166 chr1:231502310 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.16 -0.52 7.15e-25 Hemoglobin concentration; LIHC cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.93 15.84 0.65 9.35e-43 Platelet count; LIHC cis rs11098499 0.909 rs9994810 chr4:120381590 A/G cg09307838 chr4:120376055 NA 0.79 12.59 0.56 3.89e-30 Corneal astigmatism; LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11466908 chr9:94123704 AUH -0.54 -6.93 -0.35 2.15e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2274273 0.870 rs11625423 chr14:55795913 G/A cg01864836 chr14:55583639 NA -0.37 -6.57 -0.33 1.9e-10 Protein biomarker; LIHC cis rs7534824 0.625 rs7521668 chr1:101491108 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.65 -6.83 -0.35 3.99e-11 Refractive astigmatism; LIHC cis rs4319547 0.656 rs10734918 chr12:122921512 A/C cg23029597 chr12:123009494 RSRC2 -0.52 -7.39 -0.37 1.15e-12 Body mass index; LIHC cis rs17818399 0.962 rs2122715 chr2:46845849 A/G cg02822958 chr2:46747628 ATP6V1E2 0.49 7.36 0.37 1.4e-12 Height; LIHC cis rs2180341 0.961 rs9375501 chr6:127652539 C/T cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs25645 0.823 rs12453334 chr17:38153473 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.86 0.65 7.5e-43 Myeloid white cell count; LIHC cis rs7980687 0.657 rs10744151 chr12:123723735 G/C cg00376283 chr12:123451042 ABCB9 0.69 10.45 0.49 2.24e-22 Height;Educational attainment;Head circumference (infant); LIHC cis rs4319547 0.661 rs10773172 chr12:122939655 G/A cg23029597 chr12:123009494 RSRC2 -0.43 -6.13 -0.31 2.37e-9 Body mass index; LIHC cis rs7617773 0.817 rs11130162 chr3:48297611 A/G cg11946769 chr3:48343235 NME6 0.64 8.74 0.43 1.03e-16 Coronary artery disease; LIHC cis rs9911578 0.805 rs1811202 chr17:56454435 T/G cg05425664 chr17:57184151 TRIM37 0.49 6.67 0.34 1.04e-10 Intelligence (multi-trait analysis); LIHC cis rs9733 0.688 rs12725667 chr1:150766070 A/T cg17724175 chr1:150552817 MCL1 -0.37 -7.39 -0.37 1.15e-12 Tonsillectomy; LIHC cis rs7647973 1.000 rs73088137 chr3:49448423 G/A cg07636037 chr3:49044803 WDR6 -0.52 -6.23 -0.32 1.41e-9 Menarche (age at onset); LIHC cis rs6831352 0.734 rs3100630 chr4:100031715 T/A cg12011299 chr4:100065546 ADH4 0.56 9.87 0.47 2.2e-20 Alcohol dependence; LIHC cis rs8060686 0.641 rs73612690 chr16:68153200 G/A cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.66e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs6674176 0.597 rs9326136 chr1:44390392 A/G cg12908607 chr1:44402522 ARTN 0.49 8.51 0.42 5.55e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2976388 0.556 rs4736300 chr8:143829269 C/T cg06565975 chr8:143823917 SLURP1 -0.43 -8.24 -0.41 3.83e-15 Urinary tract infection frequency; LIHC cis rs7940866 0.838 rs10750455 chr11:130800330 C/T cg12179176 chr11:130786555 SNX19 0.67 10.13 0.48 2.79e-21 Schizophrenia; LIHC cis rs6964587 0.773 rs2097810 chr7:91977226 G/A cg17063962 chr7:91808500 NA 0.99 17.27 0.68 1.7e-48 Breast cancer; LIHC cis rs10751667 0.621 rs7394681 chr11:952111 C/T cg10932868 chr11:921992 NA 0.39 7.29 0.37 2.22e-12 Alzheimer's disease (late onset); LIHC cis rs9911578 1.000 rs9898626 chr17:56698219 C/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.773 rs309180 chr2:136614255 A/G cg07305463 chr2:136567211 LCT -0.4 -7.98 -0.4 2.23e-14 Mosquito bite size; LIHC cis rs992157 0.775 rs1877714 chr2:219134928 A/G cg00012203 chr2:219082015 ARPC2 -0.84 -13.32 -0.58 6.49e-33 Colorectal cancer; LIHC cis rs4819052 0.851 rs4819049 chr21:46673086 C/G cg22633049 chr21:46681294 NA -0.37 -6.46 -0.33 3.6e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg08125733 chr17:73851984 WBP2 0.92 13.44 0.59 2.36e-33 Psoriasis; LIHC cis rs12744310 0.887 rs1316274 chr1:41793658 G/A cg03962019 chr1:41807865 NA 0.39 6.38 0.33 5.89e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9926296 0.572 rs8047581 chr16:89884502 C/T cg04287289 chr16:89883240 FANCA 0.56 9.47 0.46 4.75e-19 Vitiligo; LIHC cis rs6867032 1.000 rs4254943 chr5:2009878 C/T cg26168224 chr5:2018326 NA 0.31 7.76 0.39 9.92e-14 Gut microbiome composition (winter); LIHC cis rs10892173 0.566 rs10892175 chr11:117674355 G/A cg21640587 chr11:117668038 DSCAML1 0.51 6.44 0.33 3.95e-10 Myopia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18294483 chr11:96123194 JRKL;CCDC82 0.44 6.09 0.31 3.02e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17376456 0.877 rs9314093 chr5:93333347 G/A cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.53e-21 Diabetic retinopathy; LIHC cis rs72720396 0.789 rs12048450 chr1:91199660 G/A cg13456504 chr1:91191583 NA 0.51 7.36 0.37 1.38e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs11039389 1 rs11039389 chr11:47796062 T/C cg20307385 chr11:47447363 PSMC3 -0.45 -5.92 -0.3 7.87e-9 Neuroticism; LIHC cis rs6840360 0.615 rs2120098 chr4:152457180 T/A cg22705602 chr4:152727874 NA -0.31 -5.93 -0.31 7.31e-9 Intelligence (multi-trait analysis); LIHC cis rs2836950 0.545 rs2297256 chr21:40558421 C/T cg06238570 chr21:40685208 BRWD1 -0.42 -6.79 -0.34 4.84e-11 Menarche (age at onset); LIHC cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg18230493 chr5:56204884 C5orf35 -0.47 -6.33 -0.32 7.65e-10 Initial pursuit acceleration; LIHC cis rs9443189 1.000 rs1280048 chr6:76529583 C/T cg01950844 chr6:76311363 SENP6 0.52 6.42 0.33 4.57e-10 Prostate cancer; LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs1982963 1.000 rs2749876 chr14:52504397 T/G cg10843707 chr14:52510701 NID2 -0.44 -7.49 -0.38 5.74e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1005277 0.505 rs7099777 chr10:38183569 A/C cg25427524 chr10:38739819 LOC399744 0.65 12.67 0.57 2e-30 Extrinsic epigenetic age acceleration; LIHC cis rs11332131 1 rs11332131 chr17:57926391 GT/G cg13753209 chr17:57696993 CLTC 0.47 7.19 0.36 4.14e-12 Platelet distribution width; LIHC cis rs2075165 0.836 rs7512751 chr1:156234439 T/G cg10096929 chr1:156261403 TMEM79 0.39 6.33 0.32 7.66e-10 Tonsillectomy; LIHC cis rs568617 1.000 rs656980 chr11:65656282 G/A cg04055107 chr11:65626734 MUS81;CFL1 0.44 6.44 0.33 4.17e-10 Crohn's disease; LIHC trans rs116095464 0.558 rs7710005 chr5:233572 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.08 0.36 8.15e-12 Breast cancer; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg20908993 chr14:67826378 EIF2S1;ATP6V1D -0.59 -6.48 -0.33 3.22e-10 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs1707322 0.721 rs4660314 chr1:46229885 T/C cg03146154 chr1:46216737 IPP 0.58 9.84 0.47 2.83e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11122272 0.525 rs2739517 chr1:231537914 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.49 -0.49 1.66e-22 Hemoglobin concentration; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg00280220 chr17:61926910 NA 0.41 6.5 0.33 2.91e-10 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg23758822 chr17:41437982 NA 0.92 17.05 0.68 1.3e-47 Menopause (age at onset); LIHC cis rs11098499 0.954 rs56270433 chr4:120406030 C/T cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.65e-29 Corneal astigmatism; LIHC cis rs1823913 1.000 rs10445783 chr2:192101498 C/T cg12404831 chr2:192114017 MYO1B -0.35 -6.85 -0.35 3.41e-11 Obesity-related traits; LIHC cis rs727505 1.000 rs28523990 chr7:124436139 C/T cg23710748 chr7:124431027 NA -0.37 -6.38 -0.33 5.77e-10 Lewy body disease; LIHC cis rs7512552 0.839 rs12046446 chr1:150460855 T/G cg15654264 chr1:150340011 RPRD2 0.69 11.18 0.52 6.16e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs372883 0.648 rs2832297 chr21:30742996 A/C cg08807101 chr21:30365312 RNF160 0.51 5.98 0.31 5.61e-9 Pancreatic cancer; LIHC cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.48 -0.46 4.36e-19 Bipolar disorder; LIHC cis rs72781680 0.846 rs72780108 chr2:23986780 G/A cg08917208 chr2:24149416 ATAD2B 0.83 7.55 0.38 3.92e-13 Lymphocyte counts; LIHC cis rs600806 0.850 rs1880670 chr1:109941133 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs672413 0.739 rs500390 chr5:78283656 C/T cg04677158 chr5:78279841 ARSB 0.37 6.26 0.32 1.14e-9 Blood and toenail selenium levels;Blood protein levels; LIHC cis rs2991971 0.933 rs12568144 chr1:45965307 G/A cg24296786 chr1:45957014 TESK2 0.59 9.33 0.45 1.32e-18 High light scatter reticulocyte count; LIHC trans rs783540 1.000 rs6603033 chr15:83335875 A/C cg18393722 chr15:85113863 UBE2QP1 0.38 6.59 0.34 1.68e-10 Schizophrenia; LIHC cis rs7927771 0.864 rs7107726 chr11:47429245 T/A cg18512352 chr11:47633146 NA -0.25 -5.87 -0.3 1.05e-8 Subjective well-being; LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC cis rs9649213 0.593 rs6948540 chr7:97960066 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs2033711 0.728 rs4801586 chr19:58934528 A/G cg00825309 chr19:58991885 ZNF446 -0.63 -9.78 -0.47 4.42e-20 Uric acid clearance; LIHC cis rs12915845 0.529 rs7175106 chr15:89088724 G/C cg05013243 chr15:89149849 MIR1179 -0.38 -6.79 -0.34 4.94e-11 Menarche (age at onset); LIHC cis rs6952808 0.601 rs3800882 chr7:2120758 G/A cg04267008 chr7:1944627 MAD1L1 -0.5 -7.9 -0.39 3.9e-14 Bipolar disorder and schizophrenia; LIHC cis rs55882075 0.967 rs59666900 chr5:179147641 C/T cg14593053 chr5:179126677 CANX 0.4 7.24 0.36 3.01e-12 Monocyte percentage of white cells; LIHC cis rs11628318 0.853 rs7155171 chr14:103031845 C/T cg12046867 chr14:103022105 NA -0.55 -8.15 -0.4 6.87e-15 Platelet count; LIHC cis rs2070488 0.804 rs13100195 chr3:38482539 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.31 0.55 4.45e-29 Electrocardiographic conduction measures; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg27329737 chr3:150930072 P2RY14;MED12L 0.39 6.78 0.34 5.28e-11 Hepatitis; LIHC cis rs8180040 0.726 rs1869869 chr3:47027833 G/A cg27129171 chr3:47204927 SETD2 0.59 9.71 0.46 7.66e-20 Colorectal cancer; LIHC cis rs3806843 0.733 rs801181 chr5:140092814 C/T cg19875535 chr5:140030758 IK -0.4 -6.5 -0.33 2.8e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg14004847 chr7:1930337 MAD1L1 -0.45 -6.32 -0.32 8.03e-10 Bipolar disorder and schizophrenia; LIHC cis rs427394 0.632 rs377137 chr5:6740468 T/G cg10857441 chr5:6722123 POLS -0.39 -6.6 -0.34 1.56e-10 Menopause (age at onset); LIHC cis rs2637266 1.000 rs2130795 chr10:78333892 C/G cg18941641 chr10:78392320 NA 0.29 6.23 0.32 1.34e-9 Pulmonary function; LIHC cis rs5769707 0.967 rs9616327 chr22:50010891 G/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.58 -0.42 3.39e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg22903471 chr2:27725779 GCKR -0.5 -8.81 -0.43 6.48e-17 Total body bone mineral density; LIHC cis rs1707322 1.000 rs34694458 chr1:46332696 G/A cg06784218 chr1:46089804 CCDC17 0.37 6.45 0.33 3.81e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13064411 0.696 rs13066742 chr3:113208423 T/C cg18753928 chr3:113234510 CCDC52 -0.42 -6.04 -0.31 4.11e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs4727027 0.704 rs13229244 chr7:148898219 A/C cg23583168 chr7:148888333 NA 0.74 11.3 0.52 2.16e-25 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7777484 0.500 rs2533885 chr7:2835655 C/T cg18446336 chr7:2847575 GNA12 -0.33 -6.49 -0.33 3.09e-10 Height; LIHC cis rs1843834 0.539 rs2068244 chr2:225440011 A/G cg22509189 chr2:225307070 NA 0.79 10.84 0.51 1e-23 IgE levels in asthmatics (D.p. specific); LIHC cis rs992157 0.798 rs10193383 chr2:219157692 C/T cg00012203 chr2:219082015 ARPC2 0.85 13.77 0.6 1.22e-34 Colorectal cancer; LIHC cis rs611744 0.538 rs13257548 chr8:109273185 G/A cg21045802 chr8:109455806 TTC35 0.62 11.09 0.51 1.26e-24 Dupuytren's disease; LIHC cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg05590025 chr7:65112418 INTS4L2 0.58 6.43 0.33 4.21e-10 Diabetic kidney disease; LIHC cis rs9467773 1.000 rs9393729 chr6:26514166 C/T cg09904177 chr6:26538194 HMGN4 0.66 13.89 0.6 4.28e-35 Intelligence (multi-trait analysis); LIHC cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg09323728 chr8:95962352 TP53INP1 -0.28 -6.06 -0.31 3.58e-9 Type 2 diabetes; LIHC cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg10295955 chr4:187884368 NA -0.94 -21.98 -0.77 2.26e-67 Lobe attachment (rater-scored or self-reported); LIHC cis rs11718455 0.960 rs35711021 chr3:44004791 G/A cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC trans rs2749592 0.550 rs7081464 chr10:37883937 C/T cg27523141 chr10:43048294 ZNF37B -0.37 -6.3 -0.32 8.92e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 9.3 0.45 1.69e-18 Platelet count; LIHC trans rs875971 0.545 rs17138156 chr7:65714695 C/T cg26939375 chr7:64535504 NA 0.4 6.36 0.33 6.44e-10 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10168434 chr2:71295172 NAGK 0.47 6.51 0.33 2.63e-10 Lung function (FEV1/FVC); LIHC cis rs3761847 0.622 rs10818498 chr9:123787566 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 5.74 0.3 2.08e-8 Rheumatoid arthritis; LIHC cis rs12200782 0.530 rs6929908 chr6:26555289 C/A cg09904177 chr6:26538194 HMGN4 0.47 6.75 0.34 6.22e-11 Small cell lung carcinoma; LIHC cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.48 0.46 4.57e-19 Bipolar disorder; LIHC cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg13271783 chr10:134563150 INPP5A -0.6 -7.18 -0.36 4.32e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8062405 1.000 rs61737565 chr16:28855522 G/C cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2840044 1.000 rs11080357 chr17:33898933 G/A cg20932281 chr17:33905541 PEX12 0.42 5.76 0.3 1.9e-8 Response to radiotherapy in cancer (late toxicity); LIHC cis rs7493 0.755 rs13228784 chr7:94960825 A/G cg21856205 chr7:94953877 PON1 -0.48 -6.17 -0.32 1.95e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs67311347 0.824 rs73073561 chr3:40357298 G/T cg18306943 chr3:40428807 ENTPD3 0.36 5.93 0.31 7.51e-9 Renal cell carcinoma; LIHC cis rs11583043 0.872 rs1326380 chr1:101293753 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.61 7.1 0.36 7.1e-12 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1008375 0.863 rs7680984 chr4:17600884 A/G cg16339924 chr4:17578868 LAP3 0.41 5.73 0.3 2.17e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17253792 0.822 rs74940664 chr14:56135065 A/G cg01858014 chr14:56050164 KTN1 -0.66 -6.75 -0.34 6.43e-11 Putamen volume; LIHC cis rs1577917 0.958 rs12198971 chr6:86525445 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg02782426 chr3:40428986 ENTPD3 0.34 6.31 0.32 8.87e-10 Renal cell carcinoma; LIHC cis rs7107174 0.901 rs10899498 chr11:78124575 C/G cg27205649 chr11:78285834 NARS2 -0.38 -5.81 -0.3 1.42e-8 Testicular germ cell tumor; LIHC trans rs800082 1.000 rs1405596 chr3:144314033 C/G cg24215973 chr2:240111563 HDAC4 -0.5 -7.44 -0.37 8.47e-13 Smoking behavior; LIHC cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg06238570 chr21:40685208 BRWD1 0.62 7.58 0.38 3.3e-13 Cognitive function; LIHC cis rs9814567 0.752 rs13075117 chr3:134329535 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.6 9.74 0.47 6.02e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3796619 0.961 rs11732520 chr4:1074009 C/T cg27284194 chr4:1044797 NA 0.61 10.09 0.48 4.11e-21 Recombination rate (males); LIHC trans rs2727020 0.658 rs10839278 chr11:49450847 G/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.48 -0.73 2.22e-57 Coronary artery disease; LIHC cis rs1707322 1.000 rs4460583 chr1:46449918 C/G cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg26119090 chr2:26468346 HADHA;HADHB -1.14 -16.75 -0.67 2.06e-46 Gut microbiome composition (summer); LIHC cis rs903552 1.000 rs8043205 chr15:102005749 A/G cg19295451 chr15:102010161 PCSK6 -0.46 -6.32 -0.32 8.18e-10 Diabetic kidney disease; LIHC cis rs35146811 0.807 rs6953441 chr7:99617067 G/A cg13334819 chr7:99746414 C7orf59 -0.56 -7.97 -0.4 2.43e-14 Coronary artery disease; LIHC cis rs7412746 0.658 rs3768016 chr1:150809919 T/C cg17724175 chr1:150552817 MCL1 0.47 9.36 0.45 1.05e-18 Melanoma; LIHC cis rs7208859 0.623 rs1061342 chr17:29114463 G/A cg14067834 chr17:29058358 SUZ12P 0.71 7.03 0.36 1.12e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs651907 0.535 rs11716558 chr3:101528481 T/C cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg04605084 chr1:91487590 ZNF644 -0.37 -6.07 -0.31 3.44e-9 Eotaxin levels; LIHC cis rs7772486 0.790 rs9403749 chr6:146162239 A/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.3 -0.32 9.02e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6089584 0.893 rs6089305 chr20:60571817 T/C cg13770153 chr20:60521292 NA -0.35 -6.97 -0.35 1.63e-11 Body mass index; LIHC cis rs1577917 0.682 rs1173417 chr6:86403941 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.49 9.7 0.46 8.47e-20 Response to antipsychotic treatment; LIHC cis rs8180040 0.966 rs17784882 chr3:47544003 C/A cg27129171 chr3:47204927 SETD2 -0.51 -8.25 -0.41 3.54e-15 Colorectal cancer; LIHC trans rs7618501 0.602 rs2240327 chr3:50113034 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.57 9.51 0.46 3.49e-19 Intelligence (multi-trait analysis); LIHC cis rs970821 0.667 rs7013258 chr8:124745441 T/C cg00283535 chr8:124749564 ANXA13 -0.42 -7.47 -0.37 6.82e-13 Breast cancer; LIHC cis rs7572733 0.555 rs6434953 chr2:198929693 A/G cg03934865 chr2:198174659 NA 0.43 6.09 0.31 3.01e-9 Dermatomyositis; LIHC cis rs4808199 0.948 rs2074300 chr19:19380996 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.55 7.84 0.39 5.89e-14 Nonalcoholic fatty liver disease; LIHC cis rs2422052 0.614 rs13033724 chr2:118644670 C/T cg22545206 chr2:118617499 NA 0.36 6.12 0.31 2.61e-9 Mosquito bite size; LIHC trans rs6598955 0.671 rs11579354 chr1:26604071 T/G cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs10464366 0.519 rs6974609 chr7:39219149 C/T cg18850127 chr7:39170497 POU6F2 0.41 7.41 0.37 1e-12 IgG glycosylation; LIHC cis rs666930 0.519 rs662602 chr1:120266903 C/G cg19096424 chr1:120255104 PHGDH 0.9 11.84 0.54 2.46e-27 Breast cancer; LIHC cis rs4908768 0.906 rs56305243 chr1:8725420 T/C cg20416874 chr1:8611966 RERE 0.45 6.39 0.33 5.43e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg04013166 chr16:89971882 TCF25 0.61 8.54 0.42 4.6e-16 Skin colour saturation; LIHC cis rs6952808 0.500 rs3800902 chr7:2144378 C/T cg21782813 chr7:2030301 MAD1L1 0.38 6.51 0.33 2.75e-10 Bipolar disorder and schizophrenia; LIHC cis rs28830936 0.966 rs3179542 chr15:42118123 G/C cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.9 -0.3 8.75e-9 Diastolic blood pressure; LIHC cis rs7197653 0.667 rs16957831 chr16:68378341 C/T cg03983715 chr16:68378420 PRMT7 -0.51 -6.22 -0.32 1.44e-9 Magnesium levels; LIHC cis rs2303759 0.958 rs1465697 chr19:49837246 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.59 9.15 0.44 5.36e-18 Multiple sclerosis; LIHC cis rs1568889 0.838 rs6484359 chr11:28262328 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.07 0.61 8.73e-36 Bipolar disorder; LIHC cis rs74544699 1.000 rs77149208 chr4:74768731 C/A cg16072462 chr4:74847758 PF4 0.59 6.03 0.31 4.29e-9 Growth-regulated protein alpha levels; LIHC cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg07092213 chr7:1199455 ZFAND2A -0.44 -6.3 -0.32 9.01e-10 Longevity;Endometriosis; LIHC cis rs79149102 0.579 rs74023908 chr15:75310710 T/C cg09165964 chr15:75287851 SCAMP5 -0.61 -8.2 -0.41 4.95e-15 Lung cancer; LIHC cis rs875971 0.862 rs778705 chr7:65861115 G/A cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC cis rs1552244 0.572 rs67439440 chr3:10169503 C/T cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs35110281 0.715 rs2838353 chr21:45119228 C/T cg21573476 chr21:45109991 RRP1B -0.5 -9.85 -0.47 2.61e-20 Mean corpuscular volume; LIHC cis rs4144743 0.938 rs35069360 chr17:45321270 C/T cg18085866 chr17:45331354 ITGB3 -0.55 -7.81 -0.39 6.9e-14 Body mass index; LIHC cis rs7937890 0.572 rs2597202 chr11:14484645 C/T cg23387056 chr11:14280742 SPON1 -0.47 -6.11 -0.31 2.69e-9 Mitochondrial DNA levels; LIHC trans rs17685 0.535 rs41299460 chr7:75600951 G/A cg19862616 chr7:65841803 NCRNA00174 0.51 7.85 0.39 5.37e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12200782 0.530 rs6929908 chr6:26555289 C/A cg11502198 chr6:26597334 ABT1 0.83 10.64 0.5 4.86e-23 Small cell lung carcinoma; LIHC cis rs6424115 1.000 rs974698 chr1:24132785 C/T cg15997130 chr1:24165203 NA 0.47 9.71 0.46 7.47e-20 Immature fraction of reticulocytes; LIHC cis rs10206020 0.921 rs6605278 chr2:1547230 C/T cg01028140 chr2:1542097 TPO -0.45 -7.16 -0.36 4.98e-12 IgG glycosylation; LIHC cis rs9814567 1.000 rs13081177 chr3:134289860 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.14 0.32 2.3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs244293 0.965 rs2058027 chr17:53204859 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs2651899 0.867 rs2742675 chr1:3079905 A/G cg22674798 chr1:3096360 PRDM16 0.28 6.93 0.35 2.09e-11 Migraine; LIHC cis rs1401999 1.000 rs4148571 chr3:183720576 A/C cg05044414 chr3:183734942 ABCC5 0.34 5.94 0.31 6.87e-9 Anterior chamber depth; LIHC cis rs748404 0.578 rs2584701 chr15:43684939 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.55 8.64 0.42 2.16e-16 Lung cancer; LIHC cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg05555928 chr11:63887634 MACROD1 0.56 7.6 0.38 2.93e-13 Mean platelet volume; LIHC cis rs1215050 0.740 rs1084784 chr4:98961711 T/G cg05340658 chr4:99064831 C4orf37 -0.4 -6.17 -0.32 1.94e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2302190 0.769 rs8082396 chr17:56632193 C/T cg12560992 chr17:57184187 TRIM37 0.69 8.82 0.43 6.14e-17 Vitamin D levels; LIHC trans rs4843747 0.671 rs4075998 chr16:88106776 G/A cg26811252 chr16:29126840 RRN3P2 0.42 6.81 0.35 4.46e-11 Menopause (age at onset); LIHC cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg12386194 chr3:101231763 SENP7 -0.47 -7.01 -0.35 1.25e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs12477438 0.520 rs11123763 chr2:99750673 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.5 0.77 1.86e-69 Chronic sinus infection; LIHC cis rs12549902 0.966 rs4737000 chr8:41509727 A/C cg21772509 chr8:41503840 NKX6-3 0.43 6.94 0.35 1.99e-11 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs2979489 0.891 rs6982511 chr8:30355513 G/T cg26383811 chr8:30366931 RBPMS -0.75 -11.92 -0.54 1.2100000000000001e-27 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs7707921 0.767 rs3739 chr5:81569311 A/G cg15871215 chr5:81402204 ATG10 -0.7 -8.35 -0.41 1.7e-15 Breast cancer; LIHC cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg06481639 chr22:41940642 POLR3H -0.63 -5.74 -0.3 2.06e-8 Vitiligo; LIHC cis rs7772486 0.875 rs2748485 chr6:146332421 T/C cg05347473 chr6:146136440 FBXO30 0.37 6.06 0.31 3.67e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6546550 0.901 rs6721891 chr2:70146121 A/G cg02498382 chr2:70120550 SNRNP27 -0.44 -7.62 -0.38 2.57e-13 Prevalent atrial fibrillation; LIHC cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs986417 1.000 rs1474999 chr14:60905920 T/C cg27398547 chr14:60952738 C14orf39 -0.82 -9.65 -0.46 1.24e-19 Gut microbiota (bacterial taxa); LIHC cis rs11098499 0.863 rs3775849 chr4:120450908 G/C cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25005279 chr10:135113451 TUBGCP2 0.43 6.41 0.33 4.7e-10 Bilirubin levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17322444 chr19:33572249 GPATCH1 0.43 7.11 0.36 6.68e-12 Cognitive function; LIHC trans rs17685 0.697 rs2302437 chr7:75677016 G/A cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.51 -0.71 1.72e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg27286337 chr10:134555280 INPP5A 0.94 13.48 0.59 1.58e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg18306943 chr3:40428807 ENTPD3 -0.35 -5.95 -0.31 6.52e-9 Renal cell carcinoma; LIHC cis rs60871478 1.000 rs62432251 chr7:801855 T/G cg05535760 chr7:792225 HEATR2 0.8 11.32 0.52 1.89e-25 Cerebrospinal P-tau181p levels; LIHC cis rs7223966 1.000 rs2854218 chr17:61942940 A/G cg05941027 chr17:61774174 LIMD2 0.34 7.26 0.37 2.67e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg03874509 chr1:107600012 PRMT6 -0.72 -11.25 -0.52 3.45e-25 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs62103177 0.564 rs11874805 chr18:77697110 T/C cg05926928 chr17:57297772 GDPD1 0.81 9.45 0.46 5.55e-19 Opioid sensitivity; LIHC cis rs4788570 0.538 rs72797713 chr16:71534208 G/A cg06353428 chr16:71660113 MARVELD3 -1.12 -10.11 -0.48 3.32e-21 Intelligence (multi-trait analysis); LIHC cis rs875971 0.862 rs801206 chr7:66021966 C/G cg18252515 chr7:66147081 NA 0.45 6.59 0.34 1.62e-10 Aortic root size; LIHC cis rs826838 1.000 rs10880963 chr12:38748408 T/C cg13010199 chr12:38710504 ALG10B 0.64 7.62 0.38 2.59e-13 Heart rate; LIHC cis rs7872515 1.000 rs7852067 chr9:94815594 A/G cg01248375 chr9:94877805 SPTLC1 0.54 7.5 0.38 5.5e-13 Bipolar disorder and schizophrenia; LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.83 -0.3 1.3e-8 Total body bone mineral density; LIHC cis rs11229555 0.645 rs12802819 chr11:58174747 T/G cg15696309 chr11:58395628 NA -0.64 -7.47 -0.37 6.61e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4794202 0.629 rs7212099 chr17:45925890 A/G cg10638573 chr17:45915098 SCRN2 0.58 5.78 0.3 1.69e-8 Alzheimer's disease (cognitive decline); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03578541 chr16:72128063 TXNL4B;DHX38 0.48 7.21 0.36 3.67e-12 Pancreatic cancer; LIHC trans rs2243480 1.000 rs6966322 chr7:65646754 A/G cg10756647 chr7:56101905 PSPH -1.07 -13.17 -0.58 2.44e-32 Diabetic kidney disease; LIHC cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg16405210 chr4:1374714 KIAA1530 -0.43 -6.48 -0.33 3.13e-10 Obesity-related traits; LIHC cis rs7917772 0.636 rs2486757 chr10:104535145 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.49 5.78 0.3 1.64e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1538970 0.924 rs12037201 chr1:45941349 G/T cg24296786 chr1:45957014 TESK2 -0.52 -7.63 -0.38 2.32e-13 Platelet count; LIHC trans rs2206405 0.565 rs6117903 chr20:7622942 C/T cg22883290 chr2:127800646 NA 0.49 6.04 0.31 4.06e-9 Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid); LIHC cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg20090690 chr10:134436459 INPP5A 0.41 5.77 0.3 1.75e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2075371 0.897 rs1646733 chr7:134002228 C/A cg11752832 chr7:134001865 SLC35B4 0.49 7.36 0.37 1.39e-12 Mean platelet volume; LIHC cis rs2354432 0.607 rs10453880 chr1:146693689 T/C cg25205988 chr1:146714368 CHD1L 0.93 5.93 0.31 7.49e-9 Mitochondrial DNA levels; LIHC cis rs798554 0.686 rs2527690 chr7:2854250 C/T cg13628971 chr7:2884303 GNA12 0.42 6.57 0.33 1.93e-10 Height; LIHC cis rs798554 0.655 rs798492 chr7:2799184 C/T cg19717773 chr7:2847554 GNA12 0.37 6.72 0.34 7.71e-11 Height; LIHC cis rs12220238 1.000 rs11000916 chr10:75953909 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.62 6.09 0.31 3.02e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9399135 0.935 rs11754504 chr6:135321509 C/T cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.02e-11 Red blood cell count; LIHC cis rs4888262 0.508 rs6564153 chr16:74658723 A/C cg01733217 chr16:74700730 RFWD3 0.84 15.56 0.64 1.18e-41 Testicular germ cell tumor; LIHC cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg06238570 chr21:40685208 BRWD1 0.62 7.58 0.38 3.3e-13 Cognitive function; LIHC cis rs2576037 0.583 rs9954336 chr18:44465945 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.77 -0.3 1.78e-8 Personality dimensions; LIHC cis rs9733 0.650 rs61820165 chr1:150555987 C/T cg13175981 chr1:150552382 MCL1 0.62 9.58 0.46 2.08e-19 Tonsillectomy; LIHC cis rs3736485 0.934 rs2899476 chr15:51903874 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.21 -0.32 1.54e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs801193 0.904 rs4718403 chr7:66242729 C/G cg00343986 chr7:65444356 GUSB 0.41 6.1 0.31 2.9e-9 Aortic root size; LIHC cis rs9303401 0.659 rs12602808 chr17:56698420 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs1941023 0.584 rs2233253 chr11:60157166 C/T cg08716584 chr11:60157161 MS4A7 -0.36 -8.26 -0.41 3.34e-15 Congenital heart disease (maternal effect); LIHC cis rs11628318 0.539 rs57749886 chr14:103095652 C/T cg01864069 chr14:103024347 NA -0.34 -5.72 -0.3 2.32e-8 Platelet count; LIHC cis rs151997 1.000 rs26063 chr5:50216718 G/A cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs589448 0.902 rs642786 chr12:69758462 T/C cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 9.91e-21 Cerebrospinal fluid biomarker levels; LIHC cis rs1865760 1.000 rs56118523 chr6:25908975 A/G cg17691542 chr6:26056736 HIST1H1C 0.41 6.09 0.31 3.04e-9 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06778680 chr14:21979519 METTL3 0.46 6.18 0.32 1.84e-9 Lung function (FEV1/FVC); LIHC cis rs858239 0.632 rs7811903 chr7:23119056 A/G cg23682824 chr7:23144976 KLHL7 0.43 6.18 0.32 1.79e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs6831352 0.918 rs13110176 chr4:100062430 C/T cg12011299 chr4:100065546 ADH4 0.58 9.97 0.47 1.04e-20 Alcohol dependence; LIHC cis rs7520050 0.966 rs7522601 chr1:46419021 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 5.92 0.3 7.76e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg10560079 chr2:191398806 TMEM194B 0.56 8.63 0.42 2.35e-16 Pulse pressure; LIHC cis rs918629 0.724 rs10515232 chr5:95310985 A/G cg10483112 chr5:95245456 ELL2 0.36 6.12 0.31 2.63e-9 IgG glycosylation; LIHC cis rs4654899 1.000 rs10799686 chr1:21486445 A/T cg08539965 chr1:21396338 EIF4G3 -0.32 -5.73 -0.3 2.26e-8 Superior frontal gyrus grey matter volume; LIHC cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs600806 0.672 rs1144593 chr1:110030945 A/G cg02415029 chr1:110025642 ATXN7L2 0.48 6.1 0.31 2.94e-9 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.583 rs2304370 chr2:136561735 G/A cg25344623 chr2:136566232 LCT -0.38 -6.37 -0.33 6.24e-10 Corneal structure; LIHC cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.48e-11 Gut microbiome composition (summer); LIHC cis rs4819052 0.851 rs4819043 chr21:46660078 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.04e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7647973 1.000 rs3905330 chr3:49550774 A/G cg07636037 chr3:49044803 WDR6 0.52 6.56 0.33 1.96e-10 Menarche (age at onset); LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs11758351 0.660 rs75156165 chr6:26235699 C/A cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.05e-12 Gout;Renal underexcretion gout; LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg04082016 chr2:20871401 NA -0.38 -6.69 -0.34 9.21e-11 Abdominal aortic aneurysm; LIHC cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 11.68 0.53 9.51e-27 Alzheimer's disease; LIHC cis rs11871801 0.517 rs34138141 chr17:40781561 G/T cg14558262 chr17:40713999 COASY 0.54 6.95 0.35 1.83e-11 Crohn's disease; LIHC cis rs1801251 0.963 rs35362030 chr2:233612845 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.34 0.52 1.59e-25 Coronary artery disease; LIHC cis rs9902453 0.904 rs55633288 chr17:28368196 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs2204008 0.837 rs7301679 chr12:37989629 T/C cg26384229 chr12:38710491 ALG10B -0.48 -6.74 -0.34 6.91e-11 Bladder cancer; LIHC cis rs6542838 0.609 rs12712043 chr2:99541494 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.47 -0.33 3.42e-10 Fear of minor pain; LIHC cis rs10861342 1.000 rs11112403 chr12:105586649 A/G cg23923672 chr12:105501055 KIAA1033 0.64 7.65 0.38 2.03e-13 IgG glycosylation; LIHC cis rs1552244 1.000 rs7626117 chr3:10140671 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.8 -12.59 -0.56 4e-30 Alzheimer's disease; LIHC cis rs4975616 0.804 rs456366 chr5:1337070 T/C cg06550200 chr5:1325588 CLPTM1L -0.69 -10.87 -0.51 7.69e-24 Lung cancer; LIHC cis rs1580019 0.562 rs4720064 chr7:32559638 G/A cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.2 0.32 1.66e-9 Cognitive ability; LIHC cis rs2153535 0.580 rs7745043 chr6:8513507 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.74 0.54 5.88e-27 Motion sickness; LIHC cis rs6141769 0.542 rs28523897 chr20:31301248 C/T cg13636640 chr20:31349939 DNMT3B -0.32 -5.74 -0.3 2.09e-8 Subjective well-being; LIHC cis rs7572733 0.515 rs13408411 chr2:198825462 G/A cg03934865 chr2:198174659 NA 0.47 6.84 0.35 3.75e-11 Dermatomyositis; LIHC cis rs295140 0.743 rs1729412 chr2:201083598 T/C cg23649088 chr2:200775458 C2orf69 0.44 5.88 0.3 9.55e-9 QT interval; LIHC cis rs8062405 1.000 rs4788095 chr16:28831359 T/C cg07451762 chr16:28383216 NA 0.32 6.14 0.31 2.33e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7582180 0.629 rs6716636 chr2:100940067 C/G cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs61990749 0.597 rs176944 chr14:78176211 G/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.36 -0.49 4.8e-22 Fibroblast growth factor basic levels; LIHC cis rs2239547 0.522 rs2581805 chr3:52979050 T/C cg11645453 chr3:52864694 ITIH4 -0.23 -5.74 -0.3 2.14e-8 Schizophrenia; LIHC cis rs11764590 0.950 rs62444919 chr7:2109499 C/T cg23422044 chr7:1970798 MAD1L1 -0.49 -5.72 -0.3 2.3e-8 Neuroticism; LIHC trans rs3942852 0.774 rs10838814 chr11:48187178 G/A cg03929089 chr4:120376271 NA -0.55 -7.59 -0.38 3.02e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg20607798 chr8:58055168 NA 0.66 8.05 0.4 1.35e-14 Developmental language disorder (linguistic errors); LIHC cis rs11711311 1.000 rs9830975 chr3:113486019 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.14 0.44 5.78e-18 IgG glycosylation; LIHC cis rs916888 0.773 rs169201 chr17:44790203 A/G cg15921436 chr17:44337874 NA 0.66 6.62 0.34 1.37e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4820294 0.669 rs7287340 chr22:38054325 C/T cg00292662 chr22:38071168 LGALS1 0.39 6.63 0.34 1.35e-10 Fat distribution (HIV); LIHC cis rs9814567 0.806 rs2293293 chr3:134322742 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.56 -9.19 -0.45 3.83e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs921968 0.643 rs484085 chr2:219396684 C/T cg17980119 chr2:219472607 PLCD4 0.35 6.02 0.31 4.62e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs6500602 0.727 rs1477123 chr16:4560627 T/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 5.8 0.3 1.52e-8 Schizophrenia; LIHC cis rs6163 0.588 rs10786706 chr10:104500659 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.47 -6.87 -0.35 3.12e-11 Waist circumference;Hip circumference; LIHC cis rs1401454 0.967 rs11023881 chr11:16246700 T/A cg10927848 chr11:16298618 SOX6 -0.33 -6.08 -0.31 3.24e-9 Blood pressure; LIHC cis rs4819052 0.807 rs7283915 chr21:46671288 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.76 0.54 4.69e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6754311 0.731 rs10207652 chr2:136588478 T/A cg07305463 chr2:136567211 LCT 0.38 7.25 0.36 2.83e-12 Mosquito bite size; LIHC trans rs875971 0.528 rs801213 chr7:66014918 C/T cg26939375 chr7:64535504 NA -0.4 -6.31 -0.32 8.63e-10 Aortic root size; LIHC cis rs11583043 1.000 rs34915449 chr1:101476786 G/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.73 0.3 2.18e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg00656387 chr3:40428638 ENTPD3 0.5 8.41 0.41 1.16e-15 Renal cell carcinoma; LIHC cis rs9368481 0.547 rs2093303 chr6:26864406 C/T cg18867708 chr6:26865862 GUSBL1 0.55 8.51 0.42 5.55e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs4689592 0.503 rs66885632 chr4:7053738 T/C cg02503808 chr4:7069936 GRPEL1 -0.77 -10.76 -0.5 1.86e-23 Monocyte percentage of white cells; LIHC cis rs34779708 0.702 rs7087150 chr10:35542138 A/T cg03585969 chr10:35415529 CREM 0.76 10.95 0.51 3.88e-24 Inflammatory bowel disease;Crohn's disease; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg15688767 chr3:125093330 ZNF148 -0.43 -6.17 -0.32 1.94e-9 Urinary tract infection frequency; LIHC cis rs9733 0.650 rs4970923 chr1:150608300 A/G cg17724175 chr1:150552817 MCL1 -0.39 -7.88 -0.39 4.26e-14 Tonsillectomy; LIHC cis rs780096 0.587 rs4665969 chr2:27574953 C/T cg27432699 chr2:27873401 GPN1 0.51 7.69 0.38 1.62e-13 Total body bone mineral density; LIHC cis rs8016982 0.674 rs759939 chr14:81663453 G/C cg01989461 chr14:81687754 GTF2A1 0.7 14.5 0.62 1.88e-37 Schizophrenia; LIHC cis rs311392 0.554 rs2671798 chr8:55104495 C/T cg11783602 chr8:55087084 NA -0.3 -6.11 -0.31 2.73e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs4853012 0.838 rs72911122 chr2:74344119 C/G cg20891558 chr2:74357851 NA 0.82 17.05 0.68 1.3e-47 Gestational age at birth (maternal effect); LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg04282497 chr4:82350883 RASGEF1B 0.42 6.11 0.31 2.67e-9 Myopia (pathological); LIHC cis rs4144743 1.000 rs67080286 chr17:45322248 T/G cg18085866 chr17:45331354 ITGB3 -0.59 -8.57 -0.42 3.66e-16 Body mass index; LIHC cis rs3762637 0.882 rs7630833 chr3:122190424 C/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs79387448 0.745 rs17027496 chr2:103178223 T/A cg09003973 chr2:102972529 NA 0.84 7.11 0.36 6.73e-12 Gut microbiota (bacterial taxa); LIHC cis rs7000551 0.532 rs4872486 chr8:22256359 G/T cg12081754 chr8:22256438 SLC39A14 0.88 17.88 0.69 6.24e-51 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs35110281 0.805 rs4818843 chr21:45006607 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.25e-9 Mean corpuscular volume; LIHC cis rs3820068 0.705 rs927206 chr1:15893338 C/T cg17385448 chr1:15911702 AGMAT 0.4 6.7 0.34 8.78e-11 Systolic blood pressure; LIHC cis rs8072100 0.840 rs11079774 chr17:45479706 C/G cg25173405 chr17:45401733 C17orf57 -0.41 -5.71 -0.3 2.45e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs9581857 0.685 rs9319373 chr13:28042835 A/G cg22138327 chr13:27999177 GTF3A 0.79 6.07 0.31 3.39e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs1577917 0.958 rs12196377 chr6:86566775 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.46 -0.37 7.34e-13 Response to antipsychotic treatment; LIHC cis rs9467773 1.000 rs1884946 chr6:26545308 C/G cg09904177 chr6:26538194 HMGN4 0.66 13.89 0.6 4.3e-35 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.909 rs12264390 chr10:959111 T/C cg26597838 chr10:835615 NA 0.98 11.93 0.54 1.18e-27 Eosinophil percentage of granulocytes; LIHC cis rs7107174 0.792 rs10751287 chr11:78072476 T/C cg02023728 chr11:77925099 USP35 0.41 7.95 0.39 2.78e-14 Testicular germ cell tumor; LIHC cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.68 0.46 9.5e-20 Bipolar disorder; LIHC cis rs4407350 0.729 rs9819 chr22:44889386 C/T cg26276947 chr22:44892394 LDOC1L -0.31 -5.73 -0.3 2.18e-8 Intelligence (multi-trait analysis); LIHC cis rs4920343 0.645 rs685300 chr1:19067368 C/T cg19637330 chr1:19110922 NA 0.31 5.89 0.3 9.21e-9 Knee osteoarthritis; LIHC cis rs12200782 0.505 rs9295696 chr6:26550288 C/T cg12826209 chr6:26865740 GUSBL1 0.49 5.9 0.3 8.61e-9 Small cell lung carcinoma; LIHC cis rs6752107 0.512 rs1372097 chr2:234227047 T/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.39 5.84 0.3 1.2e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs11711311 1.000 rs9828449 chr3:113518602 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.01 0.44 1.52e-17 IgG glycosylation; LIHC cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg27572855 chr1:25598939 RHD 0.4 8.48 0.42 6.74e-16 Plateletcrit;Mean corpuscular volume; LIHC cis rs10256972 0.521 rs871019 chr7:1105230 A/G cg07308232 chr7:1071921 C7orf50 -0.45 -6.9 -0.35 2.56e-11 Longevity;Endometriosis; LIHC cis rs7786877 0.723 rs62482239 chr7:100217810 C/T cg00334542 chr7:100209784 MOSPD3 -0.73 -7.64 -0.38 2.23e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9303280 0.806 rs35736272 chr17:38032680 T/C cg11212589 chr17:38028394 ZPBP2 0.35 7.15 0.36 5.31e-12 Self-reported allergy; LIHC cis rs9916302 0.808 rs12948906 chr17:37644854 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.34 -0.59 5.58e-33 Glomerular filtration rate (creatinine); LIHC cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.84 0.35 3.75e-11 Gut microbiome composition (summer); LIHC trans rs2352908 1.000 rs12897476 chr14:49453299 G/T cg01449224 chr4:123073775 NA -0.47 -6.3 -0.32 9.26e-10 Social communication problems; LIHC cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.06 -0.31 3.55e-9 Colorectal cancer; LIHC cis rs4911259 0.552 rs13041458 chr20:31467376 G/T cg13636640 chr20:31349939 DNMT3B -0.62 -10.85 -0.51 9.07e-24 Inflammatory bowel disease; LIHC cis rs644799 0.511 rs10831420 chr11:95478209 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.55 7.05 0.36 9.72e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs79976124 1.000 rs79976124 chr6:66618657 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.61 6.04 0.31 3.93e-9 Type 2 diabetes; LIHC cis rs7213347 0.707 rs2038677 chr17:2178092 C/G cg15816464 chr17:2026533 SMG6 0.5 9.7 0.46 8.02e-20 Total body bone mineral density; LIHC cis rs9611565 0.503 rs5996062 chr22:42167464 C/G cg03806693 chr22:41940476 POLR3H 0.98 10.31 0.49 7.06e-22 Vitiligo; LIHC trans rs1814175 0.817 rs1794164 chr11:49899610 T/C cg03929089 chr4:120376271 NA -0.89 -18.22 -0.7 2.49e-52 Height; LIHC cis rs1371867 0.846 rs1660324 chr8:101281271 C/T cg06636551 chr8:101224915 SPAG1 -0.52 -9.37 -0.45 9.84e-19 Atrioventricular conduction; LIHC cis rs2836974 0.644 rs2836982 chr21:40689171 C/A cg06238570 chr21:40685208 BRWD1 -0.53 -8.8 -0.43 7e-17 Cognitive function; LIHC cis rs1707322 0.721 rs56255771 chr1:46224319 C/T cg03146154 chr1:46216737 IPP 0.56 9.61 0.46 1.65e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1670533 1.000 rs1010342 chr4:1068819 C/T cg27284194 chr4:1044797 NA 0.61 9.12 0.44 6.66e-18 Recombination rate (females); LIHC cis rs7615952 0.551 rs6438945 chr3:125634473 G/A cg05084668 chr3:125655381 ALG1L -0.6 -8.51 -0.42 5.57e-16 Blood pressure (smoking interaction); LIHC cis rs6912958 0.514 rs1980792 chr6:87889917 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.57 -10.48 -0.49 1.83e-22 Monocyte percentage of white cells; LIHC cis rs9503598 0.636 rs6596977 chr6:3466254 G/A cg00476032 chr6:3446245 SLC22A23 0.4 7.77 0.39 9.11e-14 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs7618501 0.633 rs13060128 chr3:50025028 A/G cg21467203 chr3:49911342 NA -0.44 -7.99 -0.4 2.11e-14 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs2554457 chr15:45520926 G/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.5 -0.38 5.55e-13 Uric acid levels; LIHC cis rs4803468 1.000 rs1043413 chr19:41939297 C/G cg14132834 chr19:41945861 ATP5SL 0.43 6.24 0.32 1.27e-9 Height; LIHC cis rs11191419 1 rs11191419 chr10:104612335 T/A cg15744005 chr10:104629667 AS3MT -0.43 -9.71 -0.46 7.75e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10504229 0.817 rs60646469 chr8:58195348 T/C cg20607798 chr8:58055168 NA 0.58 6.77 0.34 5.5e-11 Developmental language disorder (linguistic errors); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg15254632 chr17:4843418 SLC25A11;RNF167 -0.46 -7.27 -0.37 2.53e-12 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs35110281 0.627 rs1836855 chr21:44965414 C/G cg01579765 chr21:45077557 HSF2BP -0.31 -5.84 -0.3 1.22e-8 Mean corpuscular volume; LIHC cis rs2115536 0.704 rs2163005 chr15:80194480 A/G cg00225070 chr15:80189496 MTHFS 0.62 9.81 0.47 3.56e-20 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs763014 1.000 rs763014 chr16:675680 T/C cg09256448 chr16:638327 NA 0.38 6.25 0.32 1.25e-9 Height; LIHC cis rs3857067 0.806 rs17302300 chr4:95109177 T/C cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.46 -0.37 7.07e-13 QT interval; LIHC cis rs7587476 0.822 rs6726763 chr2:215681580 T/G cg04530015 chr2:215796436 ABCA12 -0.38 -6.23 -0.32 1.38e-9 Neuroblastoma; LIHC cis rs6952808 0.636 rs6964522 chr7:1953523 C/T cg04267008 chr7:1944627 MAD1L1 -0.66 -10.56 -0.5 9.45e-23 Bipolar disorder and schizophrenia; LIHC cis rs12644436 0.711 rs12646494 chr4:88788205 A/G cg06891869 chr4:88767617 MEPE 0.42 7.6 0.38 2.93e-13 HIV-1 viral setpoint; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.72 -12.26 -0.55 6.64e-29 Prudent dietary pattern; LIHC cis rs10216189 1.000 rs9986884 chr7:5527211 C/T cg05318486 chr7:5553423 FBXL18 -0.57 -8.47 -0.42 7.31e-16 Relative hand skill in reading disability; LIHC cis rs9393692 0.645 rs11756673 chr6:26323505 A/G cg00631329 chr6:26305371 NA -0.5 -7.95 -0.39 2.83e-14 Educational attainment; LIHC cis rs9790314 0.715 rs9290065 chr3:160776964 A/G cg03342759 chr3:160939853 NMD3 0.58 7.12 0.36 6.47e-12 Morning vs. evening chronotype; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg00656387 chr3:40428638 ENTPD3 -0.5 -8.65 -0.42 2.02e-16 Renal cell carcinoma; LIHC cis rs7523273 0.526 rs12132176 chr1:207884287 A/T cg22525895 chr1:207977042 MIR29B2 0.49 7.14 0.36 5.67e-12 Schizophrenia; LIHC cis rs67311347 0.605 rs1880762 chr3:40283215 A/G cg18306943 chr3:40428807 ENTPD3 0.39 6.63 0.34 1.33e-10 Renal cell carcinoma; LIHC cis rs9393692 0.875 rs9358917 chr6:26284417 T/C cg00631329 chr6:26305371 NA -0.43 -7.25 -0.36 2.88e-12 Educational attainment; LIHC cis rs11792861 0.546 rs7873569 chr9:111796753 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.46 6.62 0.34 1.4e-10 Menarche (age at onset); LIHC cis rs10779751 0.922 rs2746637 chr1:11275588 A/G cg08854313 chr1:11322531 MTOR 0.83 11.48 0.53 5.01e-26 Body mass index; LIHC cis rs1691799 0.867 rs1183274 chr12:66732057 C/G cg16791601 chr12:66731901 HELB -0.57 -13.99 -0.6 1.79e-35 White blood cell count (basophil); LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs7408868 1.000 rs10406754 chr19:15274201 T/A cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC trans rs8073060 0.505 rs225276 chr17:33973034 T/C cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg11644478 chr21:40555479 PSMG1 0.84 10.61 0.5 6.44e-23 Cognitive function; LIHC cis rs2153535 0.580 rs6912193 chr6:8456306 T/G cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC trans rs35110281 0.837 rs2838341 chr21:45076443 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.44 6.18 0.32 1.83e-9 Mean corpuscular volume; LIHC cis rs11122272 0.735 rs2355873 chr1:231477442 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.76 -0.5 1.95e-23 Hemoglobin concentration; LIHC cis rs11758351 0.587 rs10484436 chr6:26237155 C/T cg03854865 chr6:26224070 HIST1H3E 0.59 6.5 0.33 2.88e-10 Gout;Renal underexcretion gout; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs11792861 0.816 rs17792434 chr9:111667319 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.7 0.43 1.39e-16 Menarche (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26918957 chr8:22926800 TNFRSF10B 0.48 7.53 0.38 4.6e-13 Lung function (FEV1/FVC); LIHC cis rs3770081 1.000 rs76052260 chr2:86328727 A/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.44 6.11 0.31 2.74e-9 Facial emotion recognition (sad faces); LIHC cis rs6424115 0.830 rs6672157 chr1:24198840 C/G cg15997130 chr1:24165203 NA 0.37 7.39 0.37 1.1e-12 Immature fraction of reticulocytes; LIHC cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg05368731 chr17:41323189 NBR1 0.74 12.69 0.57 1.75e-30 Menopause (age at onset); LIHC cis rs6748734 0.843 rs6749674 chr2:241834501 G/C cg20140201 chr2:241835670 C2orf54 -0.46 -6.41 -0.33 4.95e-10 Urinary metabolites; LIHC cis rs903552 1.000 rs12908310 chr15:102003635 A/G cg00659931 chr15:102010125 PCSK6 -0.44 -6.04 -0.31 4.03e-9 Diabetic kidney disease; LIHC cis rs7085104 0.700 rs10883785 chr10:104603588 A/G cg15744005 chr10:104629667 AS3MT -0.4 -8.94 -0.44 2.46e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs10751667 0.580 rs11246363 chr11:971667 T/C cg06064525 chr11:970664 AP2A2 -0.56 -15.01 -0.63 1.76e-39 Alzheimer's disease (late onset); LIHC cis rs2549003 1.000 rs3846732 chr5:131816087 T/C cg21138405 chr5:131827807 IRF1 0.37 9.6 0.46 1.71e-19 Asthma (sex interaction); LIHC cis rs992157 0.775 rs7559428 chr2:219150238 A/G cg00012203 chr2:219082015 ARPC2 -0.84 -13.33 -0.58 5.97e-33 Colorectal cancer; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg14828511 chr1:107599125 PRMT6 -0.43 -6.01 -0.31 4.79e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7707921 0.767 rs226196 chr5:81576965 C/A cg15871215 chr5:81402204 ATG10 0.68 8.21 0.41 4.57e-15 Breast cancer; LIHC cis rs9534288 0.699 rs1467665 chr13:46662919 C/T cg15192986 chr13:46630673 CPB2 -0.42 -6.09 -0.31 3.06e-9 Blood protein levels; LIHC cis rs801193 1.000 rs4279493 chr7:66226620 C/T cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.63e-9 Aortic root size; LIHC cis rs1816752 0.901 rs28600047 chr13:25041108 T/C cg22771759 chr13:24902376 NA 0.32 6.56 0.33 1.99e-10 Obesity-related traits; LIHC cis rs7772486 0.846 rs9376976 chr6:146355605 T/C cg05347473 chr6:146136440 FBXO30 0.37 5.95 0.31 6.49e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9560113 1.000 rs9555811 chr13:112181532 A/C cg14154082 chr13:112174009 NA 0.3 6.26 0.32 1.16e-9 Menarche (age at onset); LIHC cis rs2153535 0.580 rs2143355 chr6:8517856 T/A cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.26e-27 Motion sickness; LIHC cis rs7116495 0.609 rs7113436 chr11:71689599 A/T cg10381502 chr11:71823885 C11orf51 0.97 8.22 0.41 4.21e-15 Severe influenza A (H1N1) infection; LIHC cis rs34779708 0.966 rs11010122 chr10:35493518 A/C cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.5e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2991971 1.000 rs2993262 chr1:46013733 G/C cg15605315 chr1:45957053 TESK2 0.45 5.9 0.3 8.75e-9 High light scatter reticulocyte count; LIHC trans rs62103177 0.810 rs62096746 chr18:77619556 T/A cg05926928 chr17:57297772 GDPD1 1.12 11.56 0.53 2.54e-26 Opioid sensitivity; LIHC cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg15691649 chr6:25882328 NA -0.53 -6.55 -0.33 2.16e-10 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs763376 chr6:8492776 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg08219700 chr8:58056026 NA 0.54 7.01 0.35 1.24e-11 Developmental language disorder (linguistic errors); LIHC cis rs12368653 0.840 rs3816896 chr12:58195773 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.55 -7.65 -0.38 2.01e-13 Multiple sclerosis; LIHC cis rs858239 0.796 rs433395 chr7:23401955 G/T cg00469287 chr7:23338798 C7orf30 0.44 5.92 0.3 8.03e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg22963979 chr7:1858916 MAD1L1 -0.38 -5.95 -0.31 6.74e-9 Bipolar disorder and schizophrenia; LIHC cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg21951975 chr1:209979733 IRF6 0.41 6.62 0.34 1.41e-10 Cleft lip with or without cleft palate; LIHC cis rs8062405 1.000 rs55719896 chr16:28846866 G/A cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4555082 0.834 rs28489970 chr14:105748862 T/C cg06808227 chr14:105710500 BRF1 -0.57 -7.6 -0.38 2.89e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg00656387 chr3:40428638 ENTPD3 0.44 7.32 0.37 1.8e-12 Renal cell carcinoma; LIHC cis rs9457247 1.000 rs2149091 chr6:167372786 C/T cg23791538 chr6:167370224 RNASET2 0.68 11.67 0.53 9.94e-27 Crohn's disease; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg00280220 chr17:61926910 NA 0.44 7.12 0.36 6.29e-12 Prudent dietary pattern; LIHC cis rs1568889 0.712 rs10835306 chr11:28302410 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 14.55 0.62 1.15e-37 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07044724 chr16:30406465 ZNF48 0.46 6.58 0.34 1.82e-10 Pancreatic cancer; LIHC cis rs2760061 0.583 rs697763 chr1:228192622 G/C cg02753203 chr1:228287806 NA 0.72 10.39 0.49 3.7e-22 Diastolic blood pressure; LIHC cis rs1577917 0.958 rs12197463 chr6:86445242 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.23 -0.32 1.39e-9 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs7748455 chr6:8453625 C/T cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.77e-28 Motion sickness; LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs10870270 0.957 rs9971084 chr10:133788747 G/C cg26149184 chr10:133730230 NA 0.49 7.83 0.39 6.16e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs858239 0.600 rs10256361 chr7:23123885 C/T cg23682824 chr7:23144976 KLHL7 0.46 6.77 0.34 5.79e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg10150615 chr22:24372951 LOC391322 -0.64 -9.67 -0.46 1e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7772486 0.597 rs7746618 chr6:146281367 T/C cg13319975 chr6:146136371 FBXO30 0.6 9.12 0.44 6.57e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs12477438 1.000 rs73963398 chr2:99887025 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.63 -8.24 -0.41 3.72e-15 Chronic sinus infection; LIHC cis rs17376456 1.000 rs13185608 chr5:93509688 T/G cg25358565 chr5:93447407 FAM172A 1.1 10.01 0.48 7.28e-21 Diabetic retinopathy; LIHC cis rs7208859 0.623 rs60890550 chr17:29030861 A/G cg13385521 chr17:29058706 SUZ12P 0.82 7.98 0.4 2.27e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg11905131 chr22:24372483 LOC391322 0.75 11.18 0.52 6.09e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6754311 0.773 rs309176 chr2:136622216 T/C cg07169764 chr2:136633963 MCM6 -0.66 -10.16 -0.48 2.25e-21 Mosquito bite size; LIHC cis rs6570726 0.935 rs447247 chr6:145812678 G/T cg23711669 chr6:146136114 FBXO30 0.55 9.82 0.47 3.32e-20 Lobe attachment (rater-scored or self-reported); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19040702 chr17:22023833 NA -0.33 -6.48 -0.33 3.11e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2228479 0.850 rs17226512 chr16:89839976 T/C cg00800038 chr16:89945340 TCF25 -0.62 -9.35 -0.45 1.2e-18 Skin colour saturation; LIHC cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg11644478 chr21:40555479 PSMG1 -0.39 -6.12 -0.31 2.55e-9 Menarche (age at onset); LIHC cis rs6570726 0.935 rs7757387 chr6:145816726 G/T cg23711669 chr6:146136114 FBXO30 0.5 8.71 0.43 1.35e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs317689 0.608 rs650198 chr12:69674595 C/T cg19645103 chr12:69753606 YEATS4 -0.46 -6.04 -0.31 3.96e-9 Response to diuretic therapy; LIHC cis rs2153535 0.580 rs1414351 chr6:8476634 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs72781680 0.784 rs12616678 chr2:24181159 G/T cg08917208 chr2:24149416 ATAD2B 0.6 5.99 0.31 5.27e-9 Lymphocyte counts; LIHC cis rs7551222 0.752 rs4252718 chr1:204512195 A/T cg20240347 chr1:204465584 NA 0.37 7.87 0.39 4.71e-14 Schizophrenia; LIHC trans rs1814175 0.619 rs10769623 chr11:49865926 C/T cg03929089 chr4:120376271 NA -0.83 -15.84 -0.65 8.89e-43 Height; LIHC cis rs36051895 0.553 rs16922773 chr9:5197436 T/G cg02405213 chr9:5042618 JAK2 -0.68 -10.78 -0.5 1.67e-23 Pediatric autoimmune diseases; LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg08469215 chr1:156261351 TMEM79 0.39 6.31 0.32 8.44e-10 Tonsillectomy; LIHC cis rs9583531 0.657 rs9521915 chr13:111384528 C/T cg15841412 chr13:111365552 ING1 0.5 6.23 0.32 1.37e-9 Coronary artery disease; LIHC cis rs1005277 0.563 rs2800550 chr10:38482929 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.28 -0.32 1.02e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4478858 0.839 rs10798834 chr1:31708977 G/A cg00250761 chr1:31883323 NA -0.27 -6.36 -0.33 6.28e-10 Alcohol dependence; LIHC cis rs13161895 1.000 rs248318 chr5:179430530 C/T cg02702477 chr5:179499311 RNF130 0.75 10.29 0.49 7.91e-22 LDL cholesterol; LIHC cis rs2421770 0.530 rs3858470 chr11:35365444 T/C cg13971030 chr11:35366721 SLC1A2 -0.45 -7.59 -0.38 3.02e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs7818688 0.697 rs11784212 chr8:95976995 G/A cg16049864 chr8:95962084 TP53INP1 0.62 6.78 0.34 5.18e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4332037 0.615 rs62435134 chr7:1895463 T/G cg23422044 chr7:1970798 MAD1L1 -0.6 -6.82 -0.35 4.1e-11 Bipolar disorder; LIHC cis rs9916302 0.904 rs8079303 chr17:37530755 G/C cg00129232 chr17:37814104 STARD3 0.4 6.34 0.32 7.45e-10 Glomerular filtration rate (creatinine); LIHC cis rs921968 0.541 rs3821031 chr2:219295249 C/T cg02985541 chr2:219472218 PLCD4 -0.41 -6.55 -0.33 2.13e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3768617 0.782 rs10911211 chr1:183022299 A/T ch.1.3577855R chr1:183094577 LAMC1 0.48 7.7 0.38 1.51e-13 Fuchs's corneal dystrophy; LIHC cis rs9394841 0.646 rs9471676 chr6:41815192 C/T cg17623882 chr6:41773611 USP49 -0.43 -5.78 -0.3 1.68e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs7572733 0.534 rs700667 chr2:198677508 T/C cg10820045 chr2:198174542 NA 0.46 7.02 0.35 1.21e-11 Dermatomyositis; LIHC cis rs10760123 1 rs10760123 chr9:123650534 T/G cg14580859 chr9:123691850 NA 0.37 6.53 0.33 2.41e-10 Allergic disease (asthma, hay fever or eczema); LIHC trans rs801193 0.904 rs4718405 chr7:66254646 A/G cg26939375 chr7:64535504 NA 0.39 6.11 0.31 2.69e-9 Aortic root size; LIHC cis rs864643 1.000 rs1768262 chr3:39553276 A/G cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs7520050 0.931 rs6688365 chr1:46329884 G/C cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06781563 chr16:85646914 KIAA0182 0.46 6.58 0.34 1.76e-10 Lung function (FEV1/FVC); LIHC cis rs16828019 0.852 rs12729448 chr1:41509834 G/A cg03387723 chr1:41708464 SCMH1 -0.41 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs7312933 0.702 rs10785333 chr12:42586470 A/G cg01256987 chr12:42539512 GXYLT1 0.41 6.89 0.35 2.69e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs881375 0.933 rs7031096 chr9:123694942 T/C cg14580859 chr9:123691850 NA 0.39 6.96 0.35 1.73e-11 Rheumatoid arthritis; LIHC cis rs2204008 0.837 rs11180821 chr12:38242843 A/G cg26384229 chr12:38710491 ALG10B 0.83 10.63 0.5 5.55e-23 Bladder cancer; LIHC cis rs6840360 1.000 rs1355413 chr4:152633667 C/T cg22705602 chr4:152727874 NA -0.32 -6.92 -0.35 2.19e-11 Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01301323 chr12:77252588 CSRP2 0.54 7.7 0.38 1.47e-13 Systolic blood pressure; LIHC cis rs11605275 1.000 rs11603592 chr11:20023522 C/T cg14835545 chr11:20032148 NAV2 -0.81 -7.58 -0.38 3.31e-13 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs796364 0.616 rs2689762 chr2:200687204 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.2 0.32 1.62e-9 Schizophrenia; LIHC cis rs3736594 0.513 rs60854669 chr2:27786929 T/C cg27432699 chr2:27873401 GPN1 0.46 6.75 0.34 6.44e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs57221529 0.713 rs12521091 chr5:590710 G/T cg09021430 chr5:549028 NA -0.43 -8.2 -0.41 4.96e-15 Lung disease severity in cystic fibrosis; LIHC cis rs7091068 0.522 rs866674 chr10:95487515 A/G cg20715218 chr10:95462985 C10orf4 0.54 6.11 0.31 2.67e-9 Urinary tract infection frequency; LIHC cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg12463550 chr7:65579703 CRCP 0.71 7.26 0.37 2.63e-12 Diabetic kidney disease; LIHC trans rs875971 0.929 rs778692 chr7:65872449 A/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs875971 0.929 rs10950041 chr7:65973875 T/C cg18876405 chr7:65276391 NA 0.37 6.67 0.34 1.04e-10 Aortic root size; LIHC cis rs8017423 0.967 rs61592400 chr14:90703252 T/C cg04374321 chr14:90722782 PSMC1 0.75 14.44 0.62 3e-37 Mortality in heart failure; LIHC cis rs1707322 0.752 rs28719889 chr1:46202283 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2404602 1.000 rs6495206 chr15:76870963 C/T cg03037974 chr15:76606532 NA 0.71 13.86 0.6 5.53e-35 Blood metabolite levels; LIHC cis rs6089584 1.000 rs6089585 chr20:60564395 G/A cg13770153 chr20:60521292 NA -0.35 -6.9 -0.35 2.53e-11 Body mass index; LIHC cis rs67460515 0.563 rs11720263 chr3:160848293 T/C cg03342759 chr3:160939853 NMD3 -0.62 -9.13 -0.44 6.11e-18 Parkinson's disease; LIHC trans rs7613875 0.620 rs13079006 chr3:49996924 G/T cg21659725 chr3:3221576 CRBN 0.54 8.08 0.4 1.09e-14 Body mass index; LIHC cis rs17376456 0.877 rs56373208 chr5:93491276 C/A cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.58e-21 Diabetic retinopathy; LIHC cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg09904177 chr6:26538194 HMGN4 -0.55 -11.03 -0.51 2.16e-24 Intelligence (multi-trait analysis); LIHC cis rs9596863 0.898 rs7983436 chr13:54388598 T/A ch.13.53330881F chr13:54432880 NA 0.43 5.73 0.3 2.21e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2251381 0.750 rs2255055 chr21:30537045 C/T cg24692254 chr21:30365293 RNF160 0.71 11.01 0.51 2.46e-24 Selective IgA deficiency; LIHC cis rs7617773 0.817 rs13094727 chr3:48323489 G/A cg11946769 chr3:48343235 NME6 0.92 11.39 0.52 1.1e-25 Coronary artery disease; LIHC cis rs722599 0.683 rs10139016 chr14:75274288 T/C cg11812906 chr14:75593930 NEK9 0.43 6.51 0.33 2.63e-10 IgG glycosylation; LIHC cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.78 -5.98 -0.31 5.5e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs8016982 0.611 rs8008870 chr14:81709374 C/T cg01989461 chr14:81687754 GTF2A1 0.72 14.5 0.62 1.75e-37 Schizophrenia; LIHC trans rs7246657 0.943 rs7257672 chr19:37823859 G/C cg10208301 chr11:6592745 DNHD1 0.47 6.68 0.34 9.96e-11 Coronary artery calcification; LIHC cis rs9457247 0.765 rs9459836 chr6:167419105 G/A cg12798992 chr6:167411361 FGFR1OP 0.49 7.43 0.37 8.73e-13 Crohn's disease; LIHC cis rs992157 0.560 rs4674275 chr2:219097738 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.22 -0.55 9.39e-29 Colorectal cancer; LIHC cis rs7617773 0.778 rs11715776 chr3:48377611 G/C cg11946769 chr3:48343235 NME6 0.93 11.81 0.54 3.03e-27 Coronary artery disease; LIHC trans rs2727020 0.894 rs11040333 chr11:49346332 G/A cg03929089 chr4:120376271 NA -0.65 -9.58 -0.46 2.07e-19 Coronary artery disease; LIHC cis rs11800820 0.557 rs12045741 chr1:246664634 A/T cg16700716 chr1:246684329 NA -0.44 -7.84 -0.39 5.67e-14 Obesity-related traits; LIHC cis rs7296418 0.961 rs7957096 chr12:123544878 A/G cg05973401 chr12:123451056 ABCB9 0.51 8.17 0.4 6.11e-15 Platelet count; LIHC cis rs7131987 0.903 rs6487796 chr12:29422764 A/G cg05697976 chr12:29376483 FAR2 0.32 6.44 0.33 4.12e-10 QT interval; LIHC cis rs7772486 0.840 rs2814867 chr6:146334030 C/A cg23711669 chr6:146136114 FBXO30 0.67 11.91 0.54 1.38e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs311392 1.000 rs454064 chr8:55088336 C/T cg20636351 chr8:55087400 NA -0.4 -8.16 -0.4 6.43e-15 Pelvic organ prolapse (moderate/severe); LIHC cis rs7762018 1.000 rs4716375 chr6:170071218 A/C cg13891659 chr6:170190454 C6orf122;C6orf208 0.5 5.82 0.3 1.33e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7546668 1.000 rs10803388 chr1:15850097 G/A cg11706911 chr1:15910989 AGMAT 0.44 6.82 0.35 4.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs3962382 1 rs3962382 chr1:68165693 A/C cg10178795 chr1:68298432 GNG12 -0.44 -6.36 -0.33 6.33e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs60871478 0.947 rs62432866 chr7:809281 T/G cg05535760 chr7:792225 HEATR2 0.79 11.26 0.52 3.02e-25 Cerebrospinal P-tau181p levels; LIHC cis rs2243480 1.000 rs2243480 chr7:65599196 C/T cg12463550 chr7:65579703 CRCP 0.69 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs1030268 0.828 rs1362735 chr7:133398605 A/G cg03336402 chr7:133662267 EXOC4 -0.46 -6.51 -0.33 2.66e-10 Intelligence (multi-trait analysis); LIHC cis rs8062405 1.000 rs1987472 chr16:28825777 C/T cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.26e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs896854 0.902 rs896852 chr8:95960886 G/T cg16049864 chr8:95962084 TP53INP1 -0.67 -13.21 -0.58 1.83e-32 Type 2 diabetes; LIHC cis rs3008870 0.920 rs975452 chr1:67480190 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 15.93 0.65 3.95e-43 Lymphocyte percentage of white cells; LIHC cis rs12594515 1.000 rs7172161 chr15:45990780 A/G cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC cis rs10751667 0.643 rs10751671 chr11:944479 T/G cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.56e-13 Alzheimer's disease (late onset); LIHC cis rs883565 0.718 rs1112438 chr3:39152345 G/A cg26331595 chr3:39149181 GORASP1;TTC21A 0.46 5.8 0.3 1.48e-8 Handedness; LIHC trans rs66573146 1.000 rs6838042 chr4:6973049 G/T cg07817883 chr1:32538562 TMEM39B 1.08 8.92 0.43 2.93e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs7224314 1.000 rs8075952 chr17:65381358 C/T cg01507342 chr17:65387096 PITPNC1 -0.47 -5.95 -0.31 6.64e-9 Diisocyanate-induced asthma; LIHC cis rs57502260 0.651 rs3781586 chr11:68199393 C/A cg01657329 chr11:68192670 LRP5 -0.6 -6.77 -0.34 5.69e-11 Total body bone mineral density (age 45-60); LIHC cis rs1816752 0.837 rs7324645 chr13:25000855 A/G cg02811702 chr13:24901961 NA 0.24 6.02 0.31 4.6e-9 Obesity-related traits; LIHC trans rs6952808 0.595 rs3778982 chr7:2166233 T/C cg04565464 chr8:145669602 NFKBIL2 0.37 6.19 0.32 1.73e-9 Bipolar disorder and schizophrenia; LIHC cis rs748404 0.560 rs2255663 chr15:43829008 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.38 -6.32 -0.32 8.18e-10 Lung cancer; LIHC cis rs703842 1.000 rs10877014 chr12:58167661 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.83 13.63 0.59 4.19e-34 Multiple sclerosis; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg18538332 chr22:24372958 LOC391322 0.67 9.89 0.47 1.84e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs644799 0.965 rs10831426 chr11:95505888 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.3 0.68 1.31e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs77106637 0.530 rs7122044 chr11:72462634 A/G cg03713592 chr11:72463424 ARAP1 0.59 6.53 0.33 2.31e-10 Type 2 diabetes; LIHC cis rs7520050 0.966 rs785471 chr1:46518677 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.87 0.3 1.03e-8 Red blood cell count;Reticulocyte count; LIHC cis rs9326248 0.954 rs10790177 chr11:117048417 A/G cg10130564 chr11:117069849 TAGLN 0.35 5.9 0.3 8.53e-9 Blood protein levels; LIHC cis rs8010715 0.596 rs12435995 chr14:24589464 A/C cg23112188 chr14:24563095 PCK2 -0.32 -6.46 -0.33 3.5e-10 IgG glycosylation; LIHC cis rs7909074 0.933 rs879073 chr10:45399882 C/G cg05187965 chr10:45406764 TMEM72 -0.26 -6.55 -0.33 2.08e-10 Mean corpuscular volume; LIHC cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg02359409 chr6:42947317 PEX6 -0.47 -6.5 -0.33 2.77e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1789 0.903 rs6850422 chr4:15682437 C/T cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.89 -0.3 9.34e-9 Blood protein levels; LIHC cis rs2153535 0.580 rs6937186 chr6:8494493 A/C cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs2153535 0.580 rs9406165 chr6:8488837 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs4589502 1.000 rs7170743 chr15:67126339 T/G cg09911534 chr15:67153556 NA -0.5 -6.08 -0.31 3.18e-9 Lung cancer (smoking interaction); LIHC cis rs7208859 0.573 rs79505916 chr17:29062326 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.8 0.35 4.68e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs2777491 0.915 rs7180418 chr15:41629502 A/C cg15257565 chr10:42644887 NA 0.31 6.04 0.31 3.99e-9 Ulcerative colitis; LIHC cis rs7944735 0.564 rs58357937 chr11:47692160 C/T cg20307385 chr11:47447363 PSMC3 -0.55 -5.89 -0.3 9.23e-9 Intraocular pressure; LIHC cis rs738322 0.555 rs5756932 chr22:38546118 C/T cg25457927 chr22:38595422 NA -0.39 -9.46 -0.46 4.97e-19 Cutaneous nevi; LIHC cis rs12824058 0.831 rs4759450 chr12:130812732 G/A cg24229701 chr12:130821962 PIWIL1 0.44 6.81 0.35 4.49e-11 Menopause (age at onset); LIHC cis rs3008870 1.000 rs2755250 chr1:67495283 A/G cg02640540 chr1:67518911 SLC35D1 0.44 6.08 0.31 3.29e-9 Lymphocyte percentage of white cells; LIHC cis rs6963495 1.000 rs6963495 chr7:105166853 T/C cg19920283 chr7:105172520 RINT1 0.75 6.01 0.31 4.64e-9 Bipolar disorder (body mass index interaction); LIHC cis rs10870270 0.917 rs9971362 chr10:133790150 T/C cg17892150 chr10:133769511 PPP2R2D -0.68 -12.45 -0.56 1.32e-29 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs8067545 0.611 rs2703771 chr17:20130154 C/G cg13482628 chr17:19912719 NA -0.41 -6.71 -0.34 8.25e-11 Schizophrenia; LIHC cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg00612595 chr21:47717864 NA 0.41 6.5 0.33 2.87e-10 Testicular germ cell tumor; LIHC cis rs1707322 0.896 rs785512 chr1:46534543 A/G cg03146154 chr1:46216737 IPP -0.44 -7.02 -0.35 1.21e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11098499 0.865 rs10032158 chr4:120391632 C/T cg09307838 chr4:120376055 NA 0.77 12.18 0.55 1.32e-28 Corneal astigmatism; LIHC cis rs7296418 0.619 rs7139321 chr12:123719528 T/G cg05973401 chr12:123451056 ABCB9 0.43 6.42 0.33 4.48e-10 Platelet count; LIHC cis rs9933309 1.000 rs9933309 chr16:88844932 A/G cg07998840 chr16:88851295 FAM38A 0.49 7.02 0.36 1.17e-11 Glycated hemoglobin levels; LIHC cis rs34779708 0.931 rs12776390 chr10:35391535 T/G cg04310649 chr10:35416472 CREM -0.44 -5.94 -0.31 7.05e-9 Inflammatory bowel disease;Crohn's disease; LIHC trans rs9866825 1.000 rs9866825 chr3:8250790 A/C cg05090150 chr14:56047923 C14orf33;KTN1 -0.49 -6.66 -0.34 1.11e-10 QT interval; LIHC cis rs2404602 0.647 rs11072619 chr15:77043242 A/C cg03037974 chr15:76606532 NA -0.61 -10.37 -0.49 4.39e-22 Blood metabolite levels; LIHC cis rs2228479 0.618 rs34689166 chr16:89860697 C/T cg06558623 chr16:89946397 TCF25 0.85 11.09 0.51 1.32e-24 Skin colour saturation; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg16405210 chr4:1374714 KIAA1530 -0.89 -14.48 -0.62 2.09e-37 Longevity; LIHC cis rs3106136 0.527 rs2664872 chr4:95146952 G/A cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.32 -0.45 1.52e-18 Capecitabine sensitivity; LIHC cis rs2070488 0.965 rs3749386 chr3:38496065 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.22 0.66 2.74e-44 Electrocardiographic conduction measures; LIHC cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg19318889 chr4:1322082 MAEA 0.49 6.77 0.34 5.73e-11 Obesity-related traits; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04902049 chr1:36622448 MAP7D1 0.38 6.14 0.32 2.32e-9 Cognitive function; LIHC cis rs4820539 0.966 rs2283803 chr22:23454881 G/A cg21100191 chr22:23484243 RTDR1 0.86 15.37 0.64 6.91e-41 Bone mineral density; LIHC cis rs1005277 0.579 rs1740735 chr10:38497777 A/C cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.19 -0.32 1.73e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7927771 0.864 rs7937331 chr11:47430458 T/C cg20135002 chr11:47629003 NA 0.56 9.53 0.46 3.03e-19 Subjective well-being; LIHC cis rs1707322 1.000 rs4660896 chr1:46372416 A/G cg03146154 chr1:46216737 IPP 0.47 7.66 0.38 1.88e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg13409248 chr3:40428643 ENTPD3 -0.48 -7.99 -0.4 2.02e-14 Renal cell carcinoma; LIHC cis rs9929218 1.000 rs28549017 chr16:68758828 G/C cg01231543 chr16:68741748 NA 0.39 6.19 0.32 1.71e-9 Colorectal cancer; LIHC cis rs8017423 0.522 rs12887028 chr14:90819605 A/G cg04374321 chr14:90722782 PSMC1 -0.5 -7.39 -0.37 1.12e-12 Mortality in heart failure; LIHC cis rs600806 0.888 rs680434 chr1:109842271 C/T cg08911820 chr1:110026001 ATXN7L2 -0.53 -6.17 -0.32 1.98e-9 Intelligence (multi-trait analysis); LIHC cis rs722599 0.961 rs2359239 chr14:75326771 C/T cg08847533 chr14:75593920 NEK9 -0.47 -7.46 -0.37 7.3e-13 IgG glycosylation; LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.38 0.33 5.88e-10 Renal cell carcinoma; LIHC cis rs7264396 0.790 rs6058297 chr20:34271861 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.61 -0.53 1.76e-26 Total cholesterol levels; LIHC cis rs796364 1.000 rs35594306 chr2:200775125 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -5.78 -0.3 1.71e-8 Schizophrenia; LIHC cis rs1580019 0.534 rs13237495 chr7:32560687 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.83 0.43 5.6e-17 Cognitive ability; LIHC cis rs4919694 1.000 rs12245343 chr10:104774050 A/G cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs9549328 0.800 rs9549621 chr13:113633579 G/A cg08528486 chr13:113648767 MCF2L -0.39 -6.35 -0.32 6.69e-10 Systolic blood pressure; LIHC cis rs7937682 0.924 rs564601 chr11:111594077 T/C cg09085632 chr11:111637200 PPP2R1B -1.11 -17.24 -0.68 2.16e-48 Primary sclerosing cholangitis; LIHC cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg06634786 chr22:41940651 POLR3H -0.77 -8.22 -0.41 4.36e-15 Vitiligo; LIHC cis rs7223966 1.000 rs112143304 chr17:61822401 T/A cg05941027 chr17:61774174 LIMD2 0.36 7.06 0.36 9.16e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2075371 1.000 rs2544211 chr7:133973230 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.66 0.38 1.93e-13 Mean platelet volume; LIHC cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg13393036 chr8:95962371 TP53INP1 -0.39 -8.86 -0.43 4.36e-17 Type 2 diabetes; LIHC cis rs6546550 0.867 rs7592647 chr2:70139134 C/T cg02498382 chr2:70120550 SNRNP27 -0.45 -7.76 -0.39 9.84e-14 Prevalent atrial fibrillation; LIHC cis rs7772486 0.754 rs1415747 chr6:146077249 A/G cg23711669 chr6:146136114 FBXO30 0.73 13.36 0.59 4.87e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs10423674 0.526 rs757317 chr19:18819984 C/T cg16673477 chr19:18812017 CRTC1 -0.41 -6.56 -0.33 2.04e-10 Menarche (age at onset); LIHC cis rs6121246 0.529 rs6060134 chr20:30176794 A/G cg13852791 chr20:30311386 BCL2L1 0.71 6.25 0.32 1.26e-9 Mean corpuscular hemoglobin; LIHC cis rs9980664 1.000 rs9984973 chr21:34739174 G/C cg04842828 chr21:34696676 IFNAR1 0.48 6.35 0.32 6.92e-10 Cognitive decline (age-related); LIHC cis rs1506636 1.000 rs2402669 chr7:123297460 C/G cg03229431 chr7:123269106 ASB15 -0.6 -11.91 -0.54 1.3e-27 Plateletcrit;Platelet count; LIHC cis rs918629 0.601 rs889302 chr5:95264652 A/C cg10483112 chr5:95245456 ELL2 -0.38 -6.99 -0.35 1.43e-11 IgG glycosylation; LIHC cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg02290350 chr8:58132656 NA 0.45 8.73 0.43 1.16e-16 Developmental language disorder (linguistic errors); LIHC cis rs2997447 0.761 rs17257127 chr1:26452386 C/T cg19633962 chr1:26362018 EXTL1 -0.62 -6.16 -0.32 2.04e-9 QRS complex (12-leadsum); LIHC cis rs11628318 0.614 rs7155883 chr14:103123404 A/C cg01864069 chr14:103024347 NA 0.45 7.04 0.36 1.05e-11 Platelet count; LIHC cis rs1577917 0.916 rs4706252 chr6:86555180 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.22 -0.41 4.25e-15 Response to antipsychotic treatment; LIHC trans rs2749592 0.588 rs2505192 chr10:38395023 G/A cg17830980 chr10:43048298 ZNF37B -0.43 -7.73 -0.39 1.17e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1008375 1.000 rs6449319 chr4:17640283 T/A cg16339924 chr4:17578868 LAP3 0.44 6.04 0.31 4.03e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg11494091 chr17:61959527 GH2 -0.44 -8.18 -0.4 5.81e-15 Prudent dietary pattern; LIHC cis rs9467773 1.000 rs9467796 chr6:26568411 A/G cg11502198 chr6:26597334 ABT1 0.46 6.71 0.34 8.01e-11 Intelligence (multi-trait analysis); LIHC cis rs11663156 0.764 rs10853629 chr18:50889886 A/G cg24270629 chr18:50823537 DCC 0.48 6.53 0.33 2.33e-10 Intelligence (multi-trait analysis); LIHC cis rs7769051 0.522 rs10457596 chr6:133169974 T/G cg22852734 chr6:133119734 C6orf192 0.8 6.76 0.34 5.98e-11 Type 2 diabetes nephropathy; LIHC cis rs7312933 0.558 rs11181466 chr12:42765181 A/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.93 0.39 3.1e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs7618501 0.633 rs55751738 chr3:49972101 A/G cg21659725 chr3:3221576 CRBN 0.66 10.66 0.5 4.41e-23 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg00684032 chr4:1343700 KIAA1530 0.51 7.39 0.37 1.15e-12 Obesity-related traits; LIHC cis rs6762 0.719 rs28655651 chr11:837121 G/C cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.56 -0.46 2.47e-19 Mean platelet volume; LIHC cis rs736408 0.677 rs2286798 chr3:52821177 G/T cg18404041 chr3:52824283 ITIH1 0.61 9.92 0.47 1.53e-20 Bipolar disorder; LIHC cis rs6754311 0.550 rs12994270 chr2:136518103 T/A cg25344623 chr2:136566232 LCT 0.43 8.51 0.42 5.58e-16 Mosquito bite size; LIHC cis rs712039 0.617 rs60118041 chr17:35803252 G/A cg16670864 chr17:35848621 DUSP14 0.33 5.74 0.3 2.15e-8 Tuberculosis; LIHC cis rs7107174 0.688 rs2063724 chr11:78133077 T/C cg02023728 chr11:77925099 USP35 0.39 7.02 0.36 1.17e-11 Testicular germ cell tumor; LIHC cis rs4927850 0.794 rs4927849 chr3:195738482 A/G cg12923728 chr3:195709715 SDHAP1 -0.78 -7.04 -0.36 1.04e-11 Pancreatic cancer; LIHC cis rs2153535 0.601 rs7738877 chr6:8542230 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.26 0.41 3.23e-15 Motion sickness; LIHC cis rs743757 0.878 rs1467914 chr3:50523668 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.46 7.04 0.36 1.09e-11 Diastolic blood pressure; LIHC cis rs12477438 0.520 rs6741772 chr2:99738961 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.88 0.6 4.52e-35 Chronic sinus infection; LIHC cis rs2795502 0.882 rs2744087 chr10:43340270 A/C cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs858239 0.665 rs6964665 chr7:23211352 G/A cg18081818 chr7:23246105 NA -0.4 -5.84 -0.3 1.18e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs858239 0.601 rs12539331 chr7:23151330 A/G cg18081818 chr7:23246105 NA -0.41 -6.12 -0.31 2.57e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs950169 0.580 rs4603535 chr15:85173872 C/T cg12863693 chr15:85201151 NMB 0.48 6.83 0.35 3.9e-11 Schizophrenia; LIHC cis rs8180040 0.654 rs6773521 chr3:47234419 A/G cg16586182 chr3:47516702 SCAP 0.49 8.64 0.42 2.15e-16 Colorectal cancer; LIHC cis rs6701037 0.566 rs13373754 chr1:175139275 C/A cg17845761 chr1:175162550 KIAA0040 0.41 6.92 0.35 2.3e-11 Alcohol dependence; LIHC cis rs754466 0.580 rs10762765 chr10:79566407 T/C cg17075019 chr10:79541650 NA -0.75 -11.44 -0.53 7.18e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs801193 0.935 rs2659916 chr7:66151352 C/G cg26939375 chr7:64535504 NA 0.43 6.84 0.35 3.64e-11 Aortic root size; LIHC cis rs11690935 0.686 rs10165126 chr2:172820315 C/T cg13550731 chr2:172543902 DYNC1I2 -0.38 -6.31 -0.32 8.84e-10 Schizophrenia; LIHC cis rs9325144 0.556 rs34565156 chr12:39028239 G/A cg26384229 chr12:38710491 ALG10B -0.42 -5.94 -0.31 6.96e-9 Morning vs. evening chronotype; LIHC cis rs9543976 1.000 rs55927305 chr13:76135349 A/G cg01531495 chr13:76123901 UCHL3 -0.51 -5.98 -0.31 5.68e-9 Diabetic retinopathy; LIHC trans rs1941687 0.505 rs9956918 chr18:31315878 C/G cg27147174 chr7:100797783 AP1S1 0.43 6.53 0.33 2.44e-10 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs7818382 1.000 rs7818382 chr8:96054000 C/T cg16049864 chr8:95962084 TP53INP1 -0.53 -9.63 -0.46 1.41e-19 Alzheimer's disease (late onset); LIHC cis rs9560113 0.959 rs4771756 chr13:112176083 T/G cg14154082 chr13:112174009 NA 0.29 6.08 0.31 3.26e-9 Menarche (age at onset); LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg14709524 chr16:89940631 TCF25 0.56 7.05 0.36 9.75e-12 Skin colour saturation; LIHC cis rs55665837 0.540 rs10766192 chr11:14811686 A/G cg25251204 chr11:14927456 NA 0.41 5.93 0.31 7.23e-9 Vitamin D levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21224049 chr4:668623 ATP5I 0.48 7.62 0.38 2.56e-13 Pancreatic cancer; LIHC cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg05590025 chr7:65112418 INTS4L2 -0.56 -6.1 -0.31 2.84e-9 Diabetic kidney disease; LIHC cis rs7223966 1.000 rs12325866 chr17:61755974 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.57 0.33 1.83e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4605213 0.605 rs41524846 chr17:49252238 A/G cg00965052 chr17:49230932 NME1;NME1-NME2 0.45 6.17 0.32 1.93e-9 Height; LIHC cis rs1451375 0.652 rs1470747 chr7:50627009 C/T cg14593290 chr7:50529359 DDC 0.49 7.86 0.39 5.03e-14 Malaria; LIHC cis rs6500602 0.727 rs4786516 chr16:4578641 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.48 7.34 0.37 1.62e-12 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27289501 chr12:77378460 NA 0.4 6.17 0.32 1.91e-9 Longevity; LIHC cis rs17756712 0.666 rs6911663 chr6:633382 G/C cg14374089 chr6:596013 EXOC2 0.4 5.71 0.3 2.42e-8 Vertical cup-disc ratio; LIHC cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg15691649 chr6:25882328 NA -0.44 -7.01 -0.35 1.26e-11 Height; LIHC cis rs864643 1.000 rs602527 chr3:39568784 A/G cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs2840044 1.000 rs17637907 chr17:33891386 A/G cg20932281 chr17:33905541 PEX12 0.42 5.73 0.3 2.23e-8 Response to radiotherapy in cancer (late toxicity); LIHC cis rs9611565 0.921 rs8137373 chr22:41729216 A/G cg03806693 chr22:41940476 POLR3H 0.82 9.53 0.46 3.1e-19 Vitiligo; LIHC cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg16680214 chr1:154839983 KCNN3 -0.34 -5.82 -0.3 1.39e-8 Prostate cancer; LIHC cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg02290350 chr8:58132656 NA 0.42 7.96 0.4 2.6e-14 Developmental language disorder (linguistic errors); LIHC cis rs7592578 0.882 rs7569128 chr2:191446691 C/A cg27211696 chr2:191398769 TMEM194B 0.61 7.61 0.38 2.68e-13 Diastolic blood pressure; LIHC cis rs10751667 1.000 rs4074232 chr11:977682 C/G ch.11.42038R chr11:967971 AP2A2 0.61 11.47 0.53 5.46e-26 Alzheimer's disease (late onset); LIHC cis rs713477 0.967 rs10483642 chr14:55920460 A/G cg13175173 chr14:55914753 NA 0.32 7.26 0.37 2.68e-12 Pediatric bone mineral content (femoral neck); LIHC cis rs10751667 0.666 rs7394958 chr11:965944 C/G cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg07061783 chr6:25882402 NA 0.42 5.85 0.3 1.16e-8 Blood metabolite levels; LIHC cis rs1494950 1.000 rs4698308 chr4:14988190 C/T cg12377275 chr4:15005593 CPEB2 -0.79 -6.62 -0.34 1.35e-10 Political ideology; LIHC cis rs709400 0.628 rs2010281 chr14:103862322 G/A cg26031613 chr14:104095156 KLC1 0.79 9.91 0.47 1.65e-20 Body mass index; LIHC cis rs11864453 1.000 rs2278027 chr16:72051369 A/G cg16558253 chr16:72132732 DHX38 -0.44 -6.3 -0.32 9.07e-10 Fibrinogen levels; LIHC cis rs3008870 1.000 rs2009319 chr1:67481070 G/T cg02640540 chr1:67518911 SLC35D1 0.45 6.13 0.31 2.41e-9 Lymphocyte percentage of white cells; LIHC cis rs8083850 0.698 rs6508229 chr18:50874503 G/C cg24270629 chr18:50823537 DCC 0.53 8.03 0.4 1.53e-14 Intelligence (multi-trait analysis); LIHC cis rs1008375 0.966 rs2286773 chr4:17616214 C/A cg15017067 chr4:17643749 FAM184B 0.36 6.02 0.31 4.58e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs782590 0.967 rs2627759 chr2:55853341 T/C cg03859395 chr2:55845619 SMEK2 0.92 16.44 0.66 3.59e-45 Metabolic syndrome; LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.38 -5.75 -0.3 2.03e-8 Total body bone mineral density; LIHC cis rs1008375 0.800 rs10008598 chr4:17607323 T/C cg02297831 chr4:17616191 MED28 0.47 7.36 0.37 1.39e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7615952 0.866 rs11922276 chr3:125631326 G/T cg05084668 chr3:125655381 ALG1L -0.57 -8.14 -0.4 7.19e-15 Blood pressure (smoking interaction); LIHC cis rs8177253 0.555 rs4481157 chr3:133464684 G/A cg12373951 chr3:133503437 NA 0.42 6.93 0.35 2.15e-11 Iron status biomarkers; LIHC cis rs4975709 0.610 rs4975704 chr5:1859807 C/A cg15595755 chr5:1867978 NA 0.4 7.94 0.39 2.95e-14 Cardiovascular disease risk factors; LIHC cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.71 0.34 8.09e-11 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06513149 chr13:33002431 N4BP2L1 0.45 6.13 0.31 2.36e-9 Lung function (FEV1/FVC); LIHC cis rs10744422 0.858 rs7980541 chr12:123379477 C/T cg22842854 chr12:123319900 HIP1R -0.64 -8.24 -0.41 3.59e-15 Schizophrenia; LIHC cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg11301795 chr4:187892539 NA -0.26 -6.99 -0.35 1.44e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs8067354 0.872 rs2645488 chr17:57889405 T/G cg02344993 chr17:57696989 CLTC 0.58 9.4 0.45 7.78e-19 Hemoglobin concentration; LIHC cis rs611744 0.934 rs672591 chr8:109192453 T/A cg18478394 chr8:109455254 TTC35 0.4 6.87 0.35 3.09e-11 Dupuytren's disease; LIHC cis rs16828019 0.852 rs71648534 chr1:41613747 G/T cg20697417 chr1:41786797 NA 0.35 6.64 0.34 1.24e-10 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.790 rs6060539 chr20:34239382 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.45 -0.53 6.66e-26 Total cholesterol levels; LIHC cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg16049864 chr8:95962084 TP53INP1 0.59 9.77 0.47 4.76e-20 Type 2 diabetes; LIHC cis rs6684514 1.000 rs11264467 chr1:156273061 A/G cg16558208 chr1:156270281 VHLL -0.48 -9.04 -0.44 1.17e-17 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9814567 1.000 rs9869981 chr3:134248801 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9372253 1.000 rs2235989 chr6:110714584 A/T cg00083206 chr6:110721305 DDO -0.34 -6.79 -0.34 4.86e-11 Platelet distribution width; LIHC cis rs1555399 0.934 rs4902477 chr14:67989097 G/A cg16224230 chr14:67978224 TMEM229B -0.24 -5.74 -0.3 2.04e-8 Parkinson's disease; LIHC cis rs4638749 0.734 rs6722745 chr2:108875244 C/T cg06795125 chr2:108905320 SULT1C2 0.31 6.33 0.32 7.88e-10 Blood pressure; LIHC cis rs1401999 1.000 rs6805913 chr3:183662924 T/G cg01324343 chr3:183735012 ABCC5 0.77 13.18 0.58 2.42e-32 Anterior chamber depth; LIHC cis rs7216064 0.636 rs62084696 chr17:66038181 C/G cg12091567 chr17:66097778 LOC651250 0.86 14.84 0.63 8.69e-39 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs4665809 1.000 rs12475854 chr2:26267375 G/A cg27170947 chr2:26402098 FAM59B -0.65 -8.17 -0.4 6.17e-15 Gut microbiome composition (summer); LIHC cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.84 8.59 0.42 3.12e-16 Platelet count; LIHC cis rs61990749 0.544 rs3759728 chr14:78230159 A/T cg23188588 chr14:78226832 SNW1;C14orf178 0.62 10.29 0.49 8.26e-22 Fibroblast growth factor basic levels; LIHC cis rs9325144 0.624 rs10783330 chr12:39114084 A/G cg26384229 chr12:38710491 ALG10B -0.43 -6.27 -0.32 1.07e-9 Morning vs. evening chronotype; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg07805724 chr3:69062774 C3orf64 -0.45 -6.85 -0.35 3.55e-11 Eotaxin levels; LIHC cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.43 0.33 4.22e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg12373951 chr3:133503437 NA 0.75 13.9 0.6 4.04e-35 Iron status biomarkers; LIHC cis rs11758351 0.866 rs75091077 chr6:26207546 A/C cg11342453 chr6:26196699 NA 0.52 5.8 0.3 1.55e-8 Gout;Renal underexcretion gout; LIHC cis rs798554 0.686 rs2644298 chr7:2858448 G/C cg13628971 chr7:2884303 GNA12 0.44 6.96 0.35 1.71e-11 Height; LIHC cis rs2242116 0.592 rs6442039 chr3:46960797 C/G cg02527881 chr3:46936655 PTH1R -0.43 -8.19 -0.4 5.34e-15 Birth weight; LIHC cis rs2153535 0.541 rs6923558 chr6:8461467 T/G cg23788917 chr6:8435910 SLC35B3 0.62 8.71 0.43 1.34e-16 Motion sickness; LIHC cis rs3806843 0.705 rs35614340 chr5:140043618 C/G cg16179182 chr5:140090404 VTRNA1-1 0.38 6.16 0.32 2e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10504229 0.593 rs1442127 chr8:57992136 T/C cg02290350 chr8:58132656 NA 0.33 7.04 0.36 1.06e-11 Developmental language disorder (linguistic errors); LIHC cis rs6138458 1.000 rs227630 chr20:24913584 A/G cg26195577 chr20:24973756 C20orf3 1.12 14.83 0.63 9.49e-39 Blood protein levels; LIHC cis rs4700695 0.925 rs11958597 chr5:65417038 G/A cg21114390 chr5:65439923 SFRS12 -0.46 -6.02 -0.31 4.46e-9 Facial morphology (factor 19); LIHC cis rs16858210 0.874 rs55666767 chr3:183573235 C/T cg25686905 chr3:183603175 PARL -0.52 -9.57 -0.46 2.27e-19 Menopause (age at onset); LIHC cis rs5769765 0.862 rs7410537 chr22:50317330 G/A cg09182678 chr22:50328711 NA -0.41 -6.07 -0.31 3.48e-9 Schizophrenia; LIHC cis rs2236918 0.664 rs1776158 chr1:242017658 C/T cg17736920 chr1:242011382 EXO1 0.4 5.93 0.31 7.32e-9 Menopause (age at onset); LIHC cis rs7613875 0.620 rs34312088 chr3:50032133 C/T cg21467203 chr3:49911342 NA -0.53 -9.65 -0.46 1.16e-19 Body mass index; LIHC cis rs35740288 0.580 rs34635893 chr15:86340248 C/T cg20737812 chr15:86336631 KLHL25 -0.44 -6.1 -0.31 2.83e-9 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs1059312 0.966 rs12368452 chr12:129277164 C/A cg09035930 chr12:129282057 SLC15A4 0.69 13.02 0.58 9.69e-32 Systemic lupus erythematosus; LIHC cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg16405210 chr4:1374714 KIAA1530 -0.9 -15.26 -0.64 1.75e-40 Longevity; LIHC cis rs700651 0.821 rs771005 chr2:198675948 C/T cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.42e-11 Intracranial aneurysm; LIHC cis rs17854409 0.764 rs73613593 chr20:61471582 T/C cg07645718 chr20:61493192 TCFL5 0.79 5.98 0.31 5.7e-9 Obesity-related traits; LIHC cis rs611744 0.934 rs673356 chr8:109185159 A/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs7116495 1.000 rs947932 chr11:71656705 A/G cg26138937 chr11:71823887 C11orf51 -0.81 -7.95 -0.39 2.76e-14 Severe influenza A (H1N1) infection; LIHC cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg21782813 chr7:2030301 MAD1L1 0.51 9.08 0.44 8.57e-18 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs4764124 0.646 rs10846062 chr12:14965781 T/C cg19759883 chr12:14956454 WBP11;C12orf60 0.47 8.19 0.4 5.22e-15 Pubertal anthropometrics; LIHC cis rs10504229 1.000 rs58608483 chr8:58195269 T/G cg21448741 chr8:58168803 NA 0.34 6.1 0.31 2.94e-9 Developmental language disorder (linguistic errors); LIHC cis rs1144333 0.655 rs946164 chr1:76383286 A/T cg03433033 chr1:76189801 ACADM 0.52 7.28 0.37 2.26e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs11098499 0.775 rs10029303 chr4:120286755 T/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs3749237 0.595 rs4855839 chr3:49507847 G/A cg06212747 chr3:49208901 KLHDC8B 0.43 5.75 0.3 1.97e-8 Resting heart rate; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03538922 chr16:87737870 LOC100129637 0.39 6.08 0.31 3.22e-9 Longevity; LIHC cis rs9905704 0.647 rs12943705 chr17:57097047 T/C cg05425664 chr17:57184151 TRIM37 0.43 6.07 0.31 3.43e-9 Testicular germ cell tumor; LIHC cis rs79149102 0.579 rs7342601 chr15:75306795 G/T cg09165964 chr15:75287851 SCAMP5 0.56 7.82 0.39 6.8e-14 Lung cancer; LIHC trans rs17384439 1.000 rs17024030 chr4:96399606 A/G cg27488279 chr7:117864698 ANKRD7 -0.52 -6.1 -0.31 2.87e-9 Obsessive-compulsive symptoms; LIHC cis rs6684514 1.000 rs28372828 chr1:156253031 G/C cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs17685 0.725 rs4476928 chr7:75642107 C/A cg01364799 chr7:75623366 TMEM120A 0.51 7.79 0.39 8.37e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2629540 0.781 rs11245362 chr10:126458649 T/C cg08799069 chr10:126477246 METTL10 -0.54 -8.72 -0.43 1.24e-16 Cocaine dependence; LIHC cis rs2292096 1.000 rs2029751 chr1:200698286 A/C cg11814564 chr1:200748674 CAMSAP1L1 -0.46 -6.02 -0.31 4.41e-9 Epilepsy; LIHC cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg10755058 chr3:40428713 ENTPD3 -0.34 -5.81 -0.3 1.42e-8 Renal cell carcinoma; LIHC cis rs13108904 0.775 rs2279282 chr4:1216033 G/C cg27284194 chr4:1044797 NA 0.38 5.82 0.3 1.33e-8 Obesity-related traits; LIHC cis rs6912958 0.712 rs7755167 chr6:88338752 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.98 -0.4 2.21e-14 Monocyte percentage of white cells; LIHC cis rs3741151 1.000 rs75114310 chr11:73042047 C/T cg17517138 chr11:73019481 ARHGEF17 0.95 6.95 0.35 1.85e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs798554 0.759 rs2644291 chr7:2890456 T/C cg04166393 chr7:2884313 GNA12 0.54 8.59 0.42 3.03e-16 Height; LIHC cis rs916888 0.821 rs199525 chr17:44847834 T/G cg01570182 chr17:44337453 NA 1.0 9.71 0.46 7.65e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg13047869 chr3:10149882 C3orf24 0.55 6.93 0.35 2.08e-11 Alzheimer's disease; LIHC cis rs1552244 0.882 rs3755783 chr3:10029289 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.71 9.48 0.46 4.49e-19 Alzheimer's disease; LIHC cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.53 -0.38 4.56e-13 Bipolar disorder; LIHC cis rs9914988 0.887 rs12948575 chr17:27130520 G/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.86 -0.35 3.23e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs10751667 0.666 rs10902242 chr11:949700 G/A cg06064525 chr11:970664 AP2A2 -0.56 -15.09 -0.63 8.65e-40 Alzheimer's disease (late onset); LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg11494091 chr17:61959527 GH2 0.45 8.27 0.41 2.96e-15 Prudent dietary pattern; LIHC cis rs10791097 0.694 rs11222369 chr11:130744670 A/G cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs763121 0.815 rs12168758 chr22:38997269 C/G cg21395723 chr22:39101663 GTPBP1 0.35 6.04 0.31 3.95e-9 Menopause (age at onset); LIHC trans rs916888 0.821 rs70600 chr17:44860021 C/T cg22968622 chr17:43663579 NA 1.21 13.44 0.59 2.28e-33 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg12310025 chr6:25882481 NA -0.45 -6.73 -0.34 7.05e-11 Height; LIHC trans rs561341 1.000 rs508192 chr17:30315147 C/T cg20587970 chr11:113659929 NA 1.18 10.27 0.49 9.72e-22 Hip circumference adjusted for BMI; LIHC cis rs600806 0.713 rs12140694 chr1:109998386 C/T cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.32 -0.32 8.08e-10 Intelligence (multi-trait analysis); LIHC cis rs798554 0.679 rs1639036 chr7:2885089 G/A cg13628971 chr7:2884303 GNA12 0.59 10.16 0.48 2.26e-21 Height; LIHC cis rs765787 0.505 rs1648302 chr15:45494238 A/G cg25801113 chr15:45476975 SHF 0.41 7.04 0.36 1.05e-11 Uric acid levels; LIHC cis rs7589728 0.563 rs80324973 chr2:88447264 T/G cg07952391 chr2:88470173 THNSL2 0.79 7.52 0.38 4.77e-13 Plasma clusterin levels; LIHC cis rs13108904 0.560 rs11247994 chr4:1343720 G/A cg00684032 chr4:1343700 KIAA1530 0.58 8.47 0.42 7.25e-16 Obesity-related traits; LIHC cis rs288342 0.832 rs13509 chr2:183642878 G/A cg02625481 chr2:183667124 NA -0.29 -6.06 -0.31 3.53e-9 Recurrent major depressive disorder; LIHC cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg02931644 chr1:25747376 RHCE 0.33 7.13 0.36 5.86e-12 Erythrocyte sedimentation rate; LIHC cis rs9814567 0.752 rs13098546 chr3:134333161 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.6 9.75 0.47 5.53e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2836950 0.520 rs8133927 chr21:40689961 G/T cg11890956 chr21:40555474 PSMG1 -0.42 -6.74 -0.34 6.64e-11 Menarche (age at onset); LIHC cis rs2929278 0.617 rs3087657 chr15:44063859 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.37 6.11 0.31 2.72e-9 Schizophrenia; LIHC cis rs4638749 0.588 rs13401731 chr2:108885340 C/T cg06795125 chr2:108905320 SULT1C2 -0.37 -7.4 -0.37 1.09e-12 Blood pressure; LIHC cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1789 0.839 rs9997068 chr4:15650990 T/C cg16509355 chr4:15471240 CC2D2A -0.47 -7.21 -0.36 3.51e-12 Blood protein levels; LIHC cis rs7223966 1.000 rs7211213 chr17:61769456 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.52 6.17 0.32 1.89e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9296092 0.517 rs55963187 chr6:33523778 G/C cg13560919 chr6:33536144 NA -0.39 -6.31 -0.32 8.5e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs3008870 0.755 rs2755242 chr1:67479598 T/C cg02640540 chr1:67518911 SLC35D1 0.45 6.96 0.35 1.78e-11 Lymphocyte percentage of white cells; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg14828511 chr1:107599125 PRMT6 0.42 5.91 0.3 8.33e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7772486 0.651 rs1292338 chr6:145967471 A/C cg23711669 chr6:146136114 FBXO30 -0.62 -11.21 -0.52 4.84e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs9549367 0.789 rs9549708 chr13:113891887 A/G cg18105134 chr13:113819100 PROZ -0.67 -11.62 -0.53 1.57e-26 Platelet distribution width; LIHC cis rs11628318 0.614 rs7154538 chr14:103068112 A/G cg12046867 chr14:103022105 NA -0.49 -7.23 -0.36 3.16e-12 Platelet count; LIHC cis rs17401966 1.000 rs35837142 chr1:10322358 C/G cg15208524 chr1:10270712 KIF1B 0.45 6.5 0.33 2.82e-10 Hepatocellular carcinoma; LIHC cis rs644799 0.965 rs573758 chr11:95539591 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs34563280 1 rs34563280 chr11:47811496 CT/C cg20307385 chr11:47447363 PSMC3 0.74 10.81 0.5 1.26e-23 Plateletcrit; LIHC cis rs244293 0.730 rs3213757 chr17:53041857 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.13 -0.31 2.47e-9 Menarche (age at onset); LIHC cis rs1018836 0.923 rs2213886 chr8:91554163 G/C cg16814680 chr8:91681699 NA -0.66 -10.55 -0.5 1.04e-22 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4808199 0.894 rs9304960 chr19:19465529 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.56 8.12 0.4 8.8e-15 Nonalcoholic fatty liver disease; LIHC cis rs2281845 0.507 rs7547762 chr1:201088245 A/G cg06714761 chr1:201096289 NA 0.34 5.86 0.3 1.11e-8 Permanent tooth development; LIHC cis rs7412746 0.611 rs4509581 chr1:150774465 A/G cg18016565 chr1:150552671 MCL1 0.54 10.11 0.48 3.36e-21 Melanoma; LIHC trans rs6598955 0.671 rs12116908 chr1:26587918 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.59 -0.42 3.07e-16 Obesity-related traits; LIHC cis rs8038465 0.638 rs12594175 chr15:73973186 C/T cg15420318 chr15:73925796 NPTN 0.4 6.16 0.32 2.09e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1801251 0.778 rs809639 chr2:233731244 C/G cg25237894 chr2:233734115 C2orf82 0.59 11.96 0.54 9e-28 Coronary artery disease; LIHC cis rs6449957 0.966 rs73126520 chr5:67475425 C/T cg23036683 chr5:67512108 NA 0.48 7.05 0.36 1e-11 Cleft lip with or without cleft palate; LIHC cis rs3768617 0.510 rs3765522 chr1:183077618 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.42 0.49 2.8e-22 Fuchs's corneal dystrophy; LIHC trans rs7618501 0.633 rs55751738 chr3:49972101 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.55 8.98 0.44 1.87e-17 Intelligence (multi-trait analysis); LIHC cis rs933688 0.877 rs10474352 chr5:90732225 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.27 0.66 1.75e-44 Smoking behavior; LIHC cis rs6952808 0.771 rs10950415 chr7:1914477 A/G cg21782813 chr7:2030301 MAD1L1 0.42 7.08 0.36 8.26e-12 Bipolar disorder and schizophrenia; LIHC trans rs11165623 0.602 rs4619021 chr1:97025910 T/C cg10631902 chr5:14652156 NA -0.25 -6.42 -0.33 4.68e-10 Hip circumference;Waist circumference; LIHC cis rs7737355 0.773 rs32103 chr5:131030961 T/C cg06307176 chr5:131281290 NA 0.4 5.79 0.3 1.56e-8 Life satisfaction; LIHC cis rs7116495 0.609 rs2503 chr11:71719403 C/T cg10381502 chr11:71823885 C11orf51 1.07 9.57 0.46 2.22e-19 Severe influenza A (H1N1) infection; LIHC cis rs4561483 0.771 rs12924398 chr16:11972948 T/A cg08843971 chr16:11963173 GSPT1 -0.33 -6.85 -0.35 3.52e-11 Testicular germ cell tumor; LIHC cis rs1008375 1.000 rs3933453 chr4:17636319 A/C cg16339924 chr4:17578868 LAP3 0.44 6.13 0.31 2.4e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10751667 0.600 rs10794342 chr11:924904 C/T cg06064525 chr11:970664 AP2A2 -0.54 -14.45 -0.62 2.82e-37 Alzheimer's disease (late onset); LIHC cis rs3790844 0.876 rs61486545 chr1:200008337 G/A cg13229857 chr1:200006247 NR5A2 0.44 7.19 0.36 3.99e-12 Pancreatic cancer; LIHC cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.72 0.34 7.49e-11 Gut microbiome composition (summer); LIHC cis rs9649213 0.593 rs6949718 chr7:97924483 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.85 -0.3 1.17e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs7208859 0.623 rs170051 chr17:28914153 G/A cg13385521 chr17:29058706 SUZ12P 0.69 6.58 0.34 1.76e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs780096 0.587 rs6760828 chr2:27579231 T/C cg27432699 chr2:27873401 GPN1 -0.46 -6.53 -0.33 2.4e-10 Total body bone mineral density; LIHC cis rs12893668 0.703 rs34026011 chr14:104050883 G/A cg24130564 chr14:104152367 KLC1 -0.53 -8.43 -0.41 9.84e-16 Reticulocyte count; LIHC cis rs533581 0.873 rs579740 chr16:88973937 A/G cg03970086 chr16:88974840 CBFA2T3 -0.34 -6.71 -0.34 8.25e-11 Social autistic-like traits; LIHC cis rs1865760 0.625 rs9393681 chr6:26008260 A/G cg17691542 chr6:26056736 HIST1H1C 0.45 6.64 0.34 1.2e-10 Height; LIHC trans rs11098499 0.866 rs10518329 chr4:120401835 A/G cg25214090 chr10:38739885 LOC399744 0.48 7.87 0.39 4.85e-14 Corneal astigmatism; LIHC cis rs2845885 0.744 rs3802932 chr11:63988045 G/A cg24431193 chr11:63883947 FLRT1;MACROD1 0.69 8.97 0.44 2.01e-17 Body mass index; LIHC cis rs10464366 0.614 rs62442213 chr7:39146933 C/T cg10621924 chr7:39171070 POU6F2 0.42 6.41 0.33 4.94e-10 IgG glycosylation; LIHC cis rs11229555 0.598 rs12269888 chr11:58184336 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6748734 1.000 rs6751693 chr2:241837332 T/C cg09990169 chr2:241835740 C2orf54 -0.66 -9.09 -0.44 8.22e-18 Urinary metabolites; LIHC cis rs875971 0.862 rs10950033 chr7:65739673 A/G cg11764359 chr7:65958608 NA -0.85 -15.03 -0.63 1.49e-39 Aortic root size; LIHC cis rs4713118 0.869 rs9468214 chr6:27713299 G/C cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg00343986 chr7:65444356 GUSB 0.44 6.24 0.32 1.29e-9 Aortic root size; LIHC cis rs35110281 0.641 rs4819283 chr21:45083011 T/A cg21573476 chr21:45109991 RRP1B -0.59 -11.16 -0.52 7.41e-25 Mean corpuscular volume; LIHC cis rs57502260 0.704 rs2186937 chr11:68256847 G/A cg20283391 chr11:68216788 NA -0.5 -6.04 -0.31 4.09e-9 Total body bone mineral density (age 45-60); LIHC cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1018836 0.828 rs7014967 chr8:91557843 G/T cg16814680 chr8:91681699 NA -0.54 -8.39 -0.41 1.31e-15 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs3736485 0.932 rs28795073 chr15:51927562 C/T cg08986416 chr15:51914746 DMXL2 -0.44 -6.33 -0.32 7.52e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg15382696 chr6:118971807 C6orf204 0.62 6.03 0.31 4.36e-9 Diastolic blood pressure; LIHC cis rs2645694 0.626 rs2703129 chr4:77818548 T/C cg06046430 chr4:77819534 ANKRD56 0.49 6.51 0.33 2.66e-10 Emphysema distribution in smoking; LIHC cis rs796364 0.806 rs55985986 chr2:201120987 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.63 -6.86 -0.35 3.33e-11 Schizophrenia; LIHC cis rs3862030 0.839 rs2274351 chr10:104264107 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.58 -0.38 3.22e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs11098699 0.821 rs11942230 chr4:124199453 A/G cg09941581 chr4:124220074 SPATA5 0.31 6.2 0.32 1.6e-9 Mosquito bite size; LIHC cis rs7072216 0.763 rs7910014 chr10:100172110 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs17270561 1.000 rs79867288 chr6:25828416 A/G cg16482183 chr6:26056742 HIST1H1C 0.54 6.35 0.32 6.85e-10 Iron status biomarkers; LIHC cis rs826838 0.935 rs1601579 chr12:39178606 G/C cg26384229 chr12:38710491 ALG10B 0.85 10.99 0.51 2.87e-24 Heart rate; LIHC cis rs13401104 0.796 rs1466207 chr2:237121350 C/T cg19324714 chr2:237145437 ASB18 0.37 5.85 0.3 1.13e-8 Educational attainment; LIHC cis rs6582630 0.584 rs12832156 chr12:38419435 C/T cg26384229 chr12:38710491 ALG10B -0.46 -6.02 -0.31 4.55e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs2243480 1.000 rs709607 chr7:65449541 C/G cg07424592 chr7:64974309 NA -0.76 -8.54 -0.42 4.52e-16 Diabetic kidney disease; LIHC cis rs477692 1.000 rs577227 chr10:131404528 C/T cg19680672 chr10:131412579 MGMT -0.45 -6.88 -0.35 2.89e-11 Response to temozolomide; LIHC cis rs66573146 0.572 rs67750430 chr4:6957266 T/G cg15105060 chr4:7024189 TBC1D14 -0.66 -5.96 -0.31 6.11e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14751398 chr6:20402153 E2F3 0.42 6.67 0.34 1.04e-10 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20261243 chr20:44718728 NCOA5 0.43 6.99 0.35 1.47e-11 Cognitive function; LIHC cis rs1997103 1.000 rs10279035 chr7:55412055 C/T cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1865760 0.532 rs1061482 chr6:26086699 G/T cg17691542 chr6:26056736 HIST1H1C 0.41 5.88 0.3 9.71e-9 Height; LIHC cis rs7249142 0.549 rs3787040 chr19:19297292 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.34 -5.81 -0.3 1.4e-8 IgG glycosylation; LIHC trans rs459571 0.834 rs379417 chr9:136890704 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.59 -9.22 -0.45 3.15e-18 Platelet distribution width; LIHC cis rs1395 0.744 rs1975384 chr2:27542041 C/T cg17158414 chr2:27665306 KRTCAP3 -0.48 -5.74 -0.3 2.05e-8 Blood metabolite levels; LIHC cis rs9902453 0.904 rs11654983 chr17:28370042 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.83 -0.6 7.2e-35 Coffee consumption (cups per day); LIHC cis rs11758351 1.000 rs16891405 chr6:26204506 A/G cg03854865 chr6:26224070 HIST1H3E 0.66 7.48 0.37 6.5e-13 Gout;Renal underexcretion gout; LIHC cis rs3761218 1.000 rs4815603 chr20:3772527 A/T cg25011176 chr20:3776985 CDC25B -0.47 -6.5 -0.33 2.83e-10 Bipolar disorder; LIHC cis rs2859741 1.000 rs4653239 chr1:37509872 C/G cg09363841 chr1:37513479 NA 0.2 6.25 0.32 1.25e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs4917833 0.789 rs10786427 chr10:100218382 G/A cg19043522 chr10:100227446 HPSE2 0.4 5.78 0.3 1.65e-8 Pediatric bone mineral density (femoral neck); LIHC cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg06634786 chr22:41940651 POLR3H -0.75 -7.71 -0.38 1.35e-13 Vitiligo; LIHC cis rs4555082 0.957 rs2816622 chr14:105733114 T/C cg13114125 chr14:105738426 BRF1 -0.73 -9.76 -0.47 5.17e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs1355223 0.872 rs12802798 chr11:34747434 T/G cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.5 -0.33 2.86e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs74417235 0.684 rs13186731 chr5:154056002 C/T cg08893839 chr5:154027129 NA 0.49 6.68 0.34 9.57e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs7412746 0.611 rs4319334 chr1:150766822 G/A cg18016565 chr1:150552671 MCL1 0.5 9.46 0.46 5.19e-19 Melanoma; LIHC cis rs12477438 0.798 rs6732579 chr2:99560239 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.74 -9.2 -0.45 3.52e-18 Chronic sinus infection; LIHC cis rs10504229 0.871 rs7002070 chr8:58153817 A/G cg21724239 chr8:58056113 NA 0.42 5.87 0.3 1.04e-8 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg27286337 chr10:134555280 INPP5A 0.83 12.43 0.56 1.65e-29 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2302190 0.882 rs9903050 chr17:56636908 T/C cg05425664 chr17:57184151 TRIM37 -0.46 -5.79 -0.3 1.58e-8 Vitamin D levels; LIHC cis rs28735056 0.933 rs499260 chr18:77589689 G/A cg20368463 chr18:77673604 PQLC1 -0.38 -6.72 -0.34 7.74e-11 Schizophrenia; LIHC cis rs10504229 1.000 rs111915672 chr8:58191665 T/C cg20607798 chr8:58055168 NA 0.49 5.91 0.3 8.09e-9 Developmental language disorder (linguistic errors); LIHC cis rs1580019 0.587 rs7805311 chr7:32558302 A/G cg14728415 chr7:32535168 LSM5;AVL9 -0.42 -6.15 -0.32 2.19e-9 Cognitive ability; LIHC trans rs12310956 0.532 rs1352211 chr12:33983132 G/A cg26384229 chr12:38710491 ALG10B 0.5 6.74 0.34 6.87e-11 Morning vs. evening chronotype; LIHC cis rs10504229 0.679 rs72649120 chr8:58040308 C/T cg02290350 chr8:58132656 NA 0.32 7.07 0.36 8.87e-12 Developmental language disorder (linguistic errors); LIHC cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg04632378 chr13:21900426 NA 0.37 6.13 0.31 2.48e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs12586317 0.553 rs78124218 chr14:35570606 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.25 0.58 1.22e-32 Psoriasis; LIHC trans rs8073060 0.614 rs225279 chr17:33974214 A/G cg19694781 chr19:47549865 TMEM160 -1.24 -12.96 -0.57 1.55e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs72843506 0.656 rs58313980 chr17:19940050 A/G cg12065943 chr17:19881925 AKAP10 -0.41 -6.93 -0.35 2.14e-11 Schizophrenia; LIHC trans rs7618501 0.572 rs4688756 chr3:50040194 T/A cg21659725 chr3:3221576 CRBN 0.67 10.93 0.51 4.79e-24 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.846 rs6908063 chr6:146403618 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.81 0.3 1.46e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs57590327 0.555 rs6795133 chr3:81756267 A/G cg07356753 chr3:81810745 GBE1 -0.57 -8.75 -0.43 9.98e-17 Extraversion; LIHC cis rs10089 0.951 rs56066100 chr5:127460571 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.74 0.34 6.74e-11 Ileal carcinoids; LIHC cis rs67311347 0.955 rs9821036 chr3:40379007 A/G cg00656387 chr3:40428638 ENTPD3 0.41 6.66 0.34 1.1e-10 Renal cell carcinoma; LIHC cis rs10857712 0.950 rs10857711 chr10:135224059 G/A cg15472797 chr10:135243109 NA -0.38 -5.73 -0.3 2.22e-8 Systemic lupus erythematosus; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg22963979 chr7:1858916 MAD1L1 0.37 6.08 0.31 3.24e-9 Bipolar disorder and schizophrenia; LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg27141850 chr2:20869434 GDF7 -0.33 -6.31 -0.32 8.65e-10 Abdominal aortic aneurysm; LIHC cis rs12744310 0.887 rs35690915 chr1:41797999 T/C cg03962019 chr1:41807865 NA 0.38 6.17 0.32 1.88e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg01117627 chr14:100150713 CYP46A1 -0.49 -6.37 -0.33 6.01e-10 Electroencephalogram traits; LIHC cis rs67311347 0.911 rs6776044 chr3:40377503 T/G cg00656387 chr3:40428638 ENTPD3 0.41 6.62 0.34 1.38e-10 Renal cell carcinoma; LIHC cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -5.9 -0.3 8.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7116495 1.000 rs529522 chr11:71580562 C/G cg26138937 chr11:71823887 C11orf51 0.69 6.83 0.35 3.94e-11 Severe influenza A (H1N1) infection; LIHC cis rs1949733 0.636 rs16842498 chr4:8539529 C/T cg11789530 chr4:8429930 ACOX3 -0.58 -8.22 -0.41 4.35e-15 Response to antineoplastic agents; LIHC cis rs875971 0.825 rs6951503 chr7:65718936 T/G cg18252515 chr7:66147081 NA 0.46 6.85 0.35 3.54e-11 Aortic root size; LIHC cis rs9473924 1.000 rs9473932 chr6:50857995 G/A cg14470998 chr6:50812995 TFAP2B 0.49 7.26 0.37 2.57e-12 Body mass index; LIHC cis rs12135894 0.648 rs4648423 chr1:3765678 C/T cg26550851 chr1:3701203 LRRC47 -0.42 -6.97 -0.35 1.68e-11 Mean corpuscular volume; LIHC cis rs6582630 0.537 rs6582500 chr12:38534206 G/A cg26384229 chr12:38710491 ALG10B 0.95 12.37 0.56 2.58e-29 Drug-induced liver injury (flucloxacillin); LIHC cis rs6952808 0.609 rs6950151 chr7:1953521 T/C cg21782813 chr7:2030301 MAD1L1 0.44 7.45 0.37 7.57e-13 Bipolar disorder and schizophrenia; LIHC cis rs10791097 0.694 rs4436551 chr11:130755739 A/G cg22079354 chr11:130786696 SNX19 -0.4 -5.79 -0.3 1.61e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs3960554 0.800 rs80002395 chr7:75814902 C/T cg19862616 chr7:65841803 NCRNA00174 0.57 7.77 0.39 9.03e-14 Eotaxin levels; LIHC cis rs8114671 0.836 rs2425012 chr20:33581955 G/A cg07148914 chr20:33460835 GGT7 -0.6 -9.15 -0.44 5.4e-18 Height; LIHC cis rs508618 0.731 rs11805033 chr1:231546452 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.67 9.51 0.46 3.59e-19 Red blood cell count; LIHC cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg23205692 chr1:25664452 TMEM50A 0.4 6.5 0.33 2.81e-10 Erythrocyte sedimentation rate; LIHC cis rs12908161 0.959 rs3748376 chr15:85328352 C/T cg17507749 chr15:85114479 UBE2QP1 0.61 6.87 0.35 3.04e-11 Schizophrenia; LIHC cis rs2239547 0.607 rs9836178 chr3:52925403 T/C cg11645453 chr3:52864694 ITIH4 -0.32 -7.91 -0.39 3.49e-14 Schizophrenia; LIHC cis rs5769707 0.681 rs4824068 chr22:50024801 G/A cg01652190 chr22:50026171 C22orf34 -0.34 -7.57 -0.38 3.46e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs12477438 0.520 rs6542870 chr2:99796638 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.16 0.77 4.33e-68 Chronic sinus infection; LIHC cis rs7772486 0.790 rs2265918 chr6:146219164 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.86 -0.3 1.1e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg05368731 chr17:41323189 NBR1 0.72 12.33 0.55 3.63e-29 Menopause (age at onset); LIHC trans rs8073060 0.586 rs72828038 chr17:33893908 C/A cg19694781 chr19:47549865 TMEM160 1.23 12.6 0.56 3.64e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs8077889 0.672 rs1234612 chr17:41840802 A/G cg26893861 chr17:41843967 DUSP3 1.09 21.08 0.75 8.37e-64 Triglycerides; LIHC cis rs11758351 1.000 rs80095925 chr6:26184942 C/T cg01420254 chr6:26195488 NA 0.54 5.77 0.3 1.75e-8 Gout;Renal underexcretion gout; LIHC cis rs10927875 0.864 rs6674071 chr1:16144855 G/C cg21385522 chr1:16154831 NA -1.08 -13.65 -0.59 3.69e-34 Dilated cardiomyopathy; LIHC cis rs782590 0.935 rs782606 chr2:55886602 T/C cg18811423 chr2:55921094 PNPT1 0.97 15.57 0.64 1.04e-41 Metabolic syndrome; LIHC trans rs7395662 0.591 rs4882012 chr11:48560597 T/A cg15704280 chr7:45808275 SEPT13 -0.45 -6.64 -0.34 1.23e-10 HDL cholesterol; LIHC cis rs28830936 1.000 rs17678138 chr15:42043067 G/A cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.72 -0.3 2.33e-8 Diastolic blood pressure; LIHC cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg12373951 chr3:133503437 NA 0.49 8.15 0.4 7.14e-15 Iron status biomarkers; LIHC cis rs7116495 1.000 rs3018302 chr11:71790942 A/C cg26138937 chr11:71823887 C11orf51 -0.8 -7.86 -0.39 4.99e-14 Severe influenza A (H1N1) infection; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg02782426 chr3:40428986 ENTPD3 0.33 6.03 0.31 4.22e-9 Renal cell carcinoma; LIHC cis rs208520 0.690 rs12192710 chr6:66718137 C/T cg07460842 chr6:66804631 NA 0.78 9.03 0.44 1.31e-17 Exhaled nitric oxide output; LIHC cis rs6840360 0.571 rs4696102 chr4:152529658 C/T cg22705602 chr4:152727874 NA -0.33 -6.38 -0.33 5.81e-10 Intelligence (multi-trait analysis); LIHC cis rs7546668 1.000 rs6686890 chr1:15835414 C/G cg11706911 chr1:15910989 AGMAT 0.45 6.91 0.35 2.41e-11 Glomerular filtration rate (creatinine); LIHC cis rs735396 1.000 rs2259816 chr12:121435587 A/C cg02403541 chr12:121454288 C12orf43 -0.46 -8.23 -0.41 4.03e-15 N-glycan levels; LIHC cis rs801193 0.935 rs2659899 chr7:66186721 A/G cg00343986 chr7:65444356 GUSB 0.41 6.24 0.32 1.28e-9 Aortic root size; LIHC cis rs12579753 1.000 rs11115017 chr12:82176914 C/A cg07988820 chr12:82153109 PPFIA2 -0.49 -6.04 -0.31 4.12e-9 Resting heart rate; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22603710 chr3:134514098 EPHB1 0.49 6.55 0.33 2.11e-10 Lung function (FEV1/FVC); LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg06558623 chr16:89946397 TCF25 0.99 15.31 0.64 1.13e-40 Skin colour saturation; LIHC cis rs7027203 0.828 rs4744291 chr9:96598297 A/G cg13679303 chr9:96623674 NA -0.3 -6.65 -0.34 1.15e-10 DNA methylation (variation); LIHC cis rs752010 0.806 rs4457567 chr1:42091407 C/T cg06885757 chr1:42089581 HIVEP3 0.28 5.77 0.3 1.82e-8 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs12431939 1.000 rs11845886 chr14:51635873 G/A cg23942311 chr14:51606299 NA -0.35 -5.85 -0.3 1.14e-8 Cancer; LIHC cis rs17253792 0.822 rs77676035 chr14:56096229 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs950776 0.518 rs12906284 chr15:78825105 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs7589728 0.563 rs78168096 chr2:88473575 G/A cg14558114 chr2:88469736 THNSL2 0.64 6.21 0.32 1.56e-9 Plasma clusterin levels; LIHC cis rs1023500 0.505 rs134889 chr22:42674350 A/T cg15557168 chr22:42548783 NA -0.37 -6.35 -0.32 6.86e-10 Schizophrenia; LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg16145915 chr7:1198662 ZFAND2A -0.41 -11.19 -0.52 5.63e-25 Longevity;Endometriosis; LIHC trans rs1005277 0.522 rs1208681 chr10:38092975 C/T cg27523141 chr10:43048294 ZNF37B 0.39 6.75 0.34 6.38e-11 Extrinsic epigenetic age acceleration; LIHC cis rs67311347 1.000 rs2305522 chr3:40429358 A/G cg13409248 chr3:40428643 ENTPD3 0.4 6.56 0.33 2.02e-10 Renal cell carcinoma; LIHC cis rs7707921 0.767 rs6880209 chr5:81574182 C/T cg15871215 chr5:81402204 ATG10 -0.66 -8.03 -0.4 1.63e-14 Breast cancer; LIHC cis rs711245 0.574 rs1179494 chr2:36809496 C/G cg09467607 chr2:36825704 FEZ2 -0.37 -6.08 -0.31 3.2e-9 Height; LIHC cis rs172166 0.694 rs203892 chr6:28067196 T/C cg25329415 chr6:28076851 NA 0.27 5.71 0.3 2.44e-8 Cardiac Troponin-T levels; LIHC cis rs4718428 0.705 rs12698547 chr7:66278258 T/C cg12165864 chr7:66369176 NA -0.47 -6.8 -0.35 4.7e-11 Corneal structure; LIHC cis rs9303401 0.614 rs34941454 chr17:57102742 T/G cg25039879 chr17:56429692 SUPT4H1 0.76 8.75 0.43 1.02e-16 Cognitive test performance; LIHC cis rs2576037 0.526 rs2051292 chr18:44484372 C/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.34 -0.32 7.46e-10 Personality dimensions; LIHC cis rs950169 0.690 rs12901166 chr15:84699113 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 6.78 0.34 5.26e-11 Schizophrenia; LIHC cis rs10838687 0.736 rs76832686 chr11:47247287 C/T cg25783544 chr11:47291846 MADD 0.49 6.18 0.32 1.84e-9 Proinsulin levels; LIHC cis rs7635838 0.859 rs34621655 chr3:11530121 T/C cg00170343 chr3:11313890 ATG7 0.39 6.03 0.31 4.35e-9 HDL cholesterol; LIHC cis rs5997397 1.000 rs5997397 chr22:29154455 A/G cg15103426 chr22:29168792 CCDC117 0.55 8.57 0.42 3.52e-16 Red cell distribution width; LIHC cis rs11098499 0.775 rs2002049 chr4:120257417 A/G cg09307838 chr4:120376055 NA 0.7 11.05 0.51 1.72e-24 Corneal astigmatism; LIHC cis rs6542838 0.553 rs6739503 chr2:99537295 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.42 -6.08 -0.31 3.17e-9 Fear of minor pain; LIHC cis rs12594515 1.000 rs6493176 chr15:45990026 A/G cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg16145915 chr7:1198662 ZFAND2A -0.38 -9.81 -0.47 3.41e-20 Longevity;Endometriosis; LIHC cis rs3816788 0.774 rs11784816 chr8:21773500 C/T cg17168535 chr8:21777572 XPO7 -0.53 -9.69 -0.46 8.91e-20 Lung cancer in ever smokers; LIHC trans rs1814175 0.791 rs1722023 chr11:49908136 G/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg03806693 chr22:41940476 POLR3H 0.97 10.23 0.48 1.33e-21 Vitiligo; LIHC cis rs7772486 0.790 rs4435956 chr6:146232403 G/C cg05347473 chr6:146136440 FBXO30 -0.36 -5.94 -0.31 6.91e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17739167 0.550 rs1426890 chr15:42226125 G/A cg20935245 chr15:42234343 EHD4 0.4 7.34 0.37 1.58e-12 Monocyte count; LIHC cis rs4689592 0.503 rs66885632 chr4:7053738 T/C cg26116260 chr4:7069785 GRPEL1 -1.0 -17.33 -0.68 9.86e-49 Monocyte percentage of white cells; LIHC cis rs600806 0.850 rs1465607 chr1:109958035 T/C cg23091122 chr1:110024289 SYPL2 -0.45 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC cis rs4700695 0.841 rs152935 chr5:65358593 A/G cg21114390 chr5:65439923 SFRS12 -0.46 -5.86 -0.3 1.1e-8 Facial morphology (factor 19); LIHC cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg17971929 chr21:40555470 PSMG1 0.84 10.13 0.48 2.88e-21 Cognitive function; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg10219037 chr11:111750118 C11orf1;FDXACB1 0.42 6.16 0.32 2.06e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs4853012 0.941 rs7571083 chr2:74342260 C/G cg01017244 chr2:74357527 NA 0.62 11.15 0.52 7.58e-25 Gestational age at birth (maternal effect); LIHC cis rs797680 0.786 rs10874772 chr1:93787770 G/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.03 -0.31 4.37e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs7512552 0.724 rs7002 chr1:150445819 A/G cg15654264 chr1:150340011 RPRD2 0.69 11.19 0.52 5.58e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg08067268 chr2:26466485 HADHB;HADHA -0.43 -6.38 -0.33 5.63e-10 Gut microbiome composition (summer); LIHC cis rs244293 0.801 rs7225949 chr17:53096771 T/C cg19360675 chr17:53046073 COX11;STXBP4 0.48 7.09 0.36 7.88e-12 Menarche (age at onset); LIHC cis rs892961 0.932 rs67719929 chr17:75412605 G/A cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs13108904 0.557 rs1250095 chr4:1239312 C/T cg05025164 chr4:1340916 KIAA1530 -0.66 -9.93 -0.47 1.36e-20 Obesity-related traits; LIHC cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.02 0.44 1.38e-17 Platelet count; LIHC cis rs9341808 0.754 rs3812126 chr6:80952701 A/G cg08355045 chr6:80787529 NA -0.36 -7.58 -0.38 3.38e-13 Sitting height ratio; LIHC cis rs80282103 0.867 rs7098169 chr10:1078601 G/A cg08668510 chr10:1095578 IDI1 0.65 6.63 0.34 1.28e-10 Glomerular filtration rate (creatinine); LIHC cis rs965469 0.779 rs6051830 chr20:3373397 T/C cg25506879 chr20:3388711 C20orf194 -0.52 -6.34 -0.32 7.07e-10 IFN-related cytopenia; LIHC cis rs10197940 0.662 rs10173699 chr2:152281561 C/G cg19508488 chr2:152266495 RIF1 -0.57 -7.91 -0.39 3.72e-14 Lung cancer; LIHC cis rs769267 0.965 rs2315024 chr19:19423817 T/A cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.91 0.47 1.66e-20 Tonsillectomy; LIHC cis rs734999 0.588 rs60520190 chr1:2533706 G/A cg18854424 chr1:2615690 NA 0.32 7.07 0.36 8.7e-12 Ulcerative colitis; LIHC cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg27286337 chr10:134555280 INPP5A 0.94 13.39 0.59 3.54e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs826838 0.904 rs7973992 chr12:39168233 T/C cg26384229 chr12:38710491 ALG10B 0.86 11.16 0.52 7.1e-25 Heart rate; LIHC cis rs9399135 0.660 rs4440481 chr6:135276696 A/G cg24558204 chr6:135376177 HBS1L 0.38 6.17 0.32 1.94e-9 Red blood cell count; LIHC cis rs9733 0.519 rs10788792 chr1:150638572 T/G cg17724175 chr1:150552817 MCL1 0.49 9.97 0.47 9.91e-21 Tonsillectomy; LIHC cis rs699 0.545 rs2478524 chr1:230836276 G/C cg07502417 chr1:230849801 AGT -0.31 -6.86 -0.35 3.31e-11 Coronary artery disease; LIHC cis rs847649 1.000 rs4620204 chr7:102594217 T/C cg18108683 chr7:102477205 FBXL13 0.48 7.42 0.37 9.13e-13 Morning vs. evening chronotype; LIHC cis rs2016586 0.894 rs1997883 chr22:36103709 C/T cg26342177 chr22:36113512 APOL5 0.39 6.48 0.33 3.19e-10 Body mass index; LIHC cis rs875971 0.798 rs57739047 chr7:65972566 A/T cg18252515 chr7:66147081 NA -0.44 -6.3 -0.32 9.26e-10 Aortic root size; LIHC cis rs4268898 1.000 rs6746005 chr2:24434345 G/A cg06627628 chr2:24431161 ITSN2 0.5 7.27 0.37 2.44e-12 Asthma; LIHC cis rs6570726 0.935 rs400968 chr6:145819718 A/G cg23711669 chr6:146136114 FBXO30 0.54 9.75 0.47 5.8e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 1.000 rs336569 chr3:161072346 T/G cg04691961 chr3:161091175 C3orf57 -0.46 -7.46 -0.37 7.12e-13 Morning vs. evening chronotype; LIHC cis rs12478296 1.000 rs73007140 chr2:243010756 T/C cg18898632 chr2:242989856 NA -0.46 -6.34 -0.32 7.1e-10 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26816438 chr1:45139524 TMEM53;C1orf228 0.43 6.64 0.34 1.23e-10 Lung function (FEV1/FVC); LIHC cis rs12765878 1.000 rs12765878 chr10:105669622 C/T cg11005552 chr10:105648138 OBFC1 -0.39 -6.22 -0.32 1.48e-9 Coronary artery disease; LIHC trans rs7246657 0.943 rs10420430 chr19:37894194 C/G cg10208301 chr11:6592745 DNHD1 0.46 6.23 0.32 1.36e-9 Coronary artery calcification; LIHC cis rs17685 0.753 rs11764129 chr7:75761890 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs769267 0.930 rs892021 chr19:19613480 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.2 0.32 1.58e-9 Tonsillectomy; LIHC cis rs963731 0.649 rs78421201 chr2:39339424 C/A cg04010122 chr2:39346883 SOS1 0.68 6.05 0.31 3.74e-9 Corticobasal degeneration; LIHC cis rs68170813 0.559 rs77422419 chr7:106957932 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.12e-9 Coronary artery disease; LIHC cis rs9816226 0.793 rs869400 chr3:185826740 T/G cg00760338 chr3:185826511 ETV5 0.69 6.25 0.32 1.22e-9 Obesity;Body mass index; LIHC cis rs12079745 0.793 rs78277513 chr1:169414777 A/C cg09363564 chr1:169337483 NME7;BLZF1 -0.71 -6.56 -0.33 1.97e-10 QT interval; LIHC trans rs66573146 0.831 rs56031152 chr4:6973832 C/A cg07817883 chr1:32538562 TMEM39B 1.11 9.39 0.45 9e-19 Granulocyte percentage of myeloid white cells; LIHC cis rs12472274 1.000 rs12472274 chr2:239095422 G/A cg17459225 chr2:239074497 NA 0.78 12.99 0.57 1.23e-31 Phospholipid levels (plasma); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg10815395 chr12:49237807 DDX23 0.41 6.1 0.31 2.91e-9 Longevity; LIHC cis rs4690686 0.769 rs7656505 chr4:177274867 A/T cg17059388 chr4:177262070 NA 0.36 6.67 0.34 1.02e-10 Essential tremor; LIHC cis rs250677 0.522 rs3763022 chr5:148381078 A/G cg18129178 chr5:148520854 ABLIM3 -0.41 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg06481639 chr22:41940642 POLR3H 0.72 7.21 0.36 3.65e-12 Vitiligo; LIHC cis rs79976124 0.876 rs17511913 chr6:66644361 C/T cg07460842 chr6:66804631 NA 0.64 6.89 0.35 2.73e-11 Type 2 diabetes; LIHC cis rs7572733 0.515 rs6726506 chr2:198846486 G/T cg00792783 chr2:198669748 PLCL1 0.45 6.56 0.33 2.04e-10 Dermatomyositis; LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs2976388 1.000 rs2920294 chr8:143765326 C/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.21e-9 Urinary tract infection frequency; LIHC cis rs921968 0.541 rs490483 chr2:219429052 A/T cg02176678 chr2:219576539 TTLL4 0.53 7.45 0.37 7.49e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs1395 0.634 rs72817542 chr2:27526681 C/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.48 -6.37 -0.33 5.96e-10 Blood metabolite levels; LIHC cis rs1580019 0.563 rs2392071 chr7:32572536 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.11 24.52 0.8 2.47e-77 Cognitive ability; LIHC cis rs7224685 0.569 rs10521129 chr17:4008820 C/T cg09695851 chr17:3907499 NA 0.61 7.44 0.37 7.96e-13 Type 2 diabetes; LIHC cis rs1865760 0.602 rs2157050 chr6:26020431 C/T cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.68e-8 Height; LIHC cis rs6088590 0.735 rs6060003 chr20:33294945 T/C cg06115741 chr20:33292138 TP53INP2 0.42 6.09 0.31 3.11e-9 Coronary artery disease; LIHC cis rs67311347 1.000 rs6599094 chr3:40399593 A/G cg16822855 chr3:40428330 ENTPD3 0.35 6.42 0.33 4.5e-10 Renal cell carcinoma; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg16218610 chr6:26124417 HIST1H2AC;HIST1H2BC -0.5 -6.19 -0.32 1.71e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs35110281 0.748 rs9981460 chr21:45030965 T/A cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.42e-23 Mean corpuscular volume; LIHC trans rs1005277 0.579 rs2474569 chr10:38383491 C/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2760061 0.583 rs708113 chr1:228192753 T/A cg01200585 chr1:228362443 C1orf69 0.46 7.05 0.36 9.73e-12 Diastolic blood pressure; LIHC cis rs7918232 0.941 rs10741128 chr10:27411509 G/A cg14442939 chr10:27389572 ANKRD26 0.72 7.07 0.36 8.65e-12 Breast cancer; LIHC cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg24549020 chr5:56110836 MAP3K1 0.51 6.56 0.33 2e-10 Initial pursuit acceleration; LIHC cis rs3736594 0.513 rs6547735 chr2:27831607 T/C cg27432699 chr2:27873401 GPN1 0.45 6.74 0.34 6.67e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg22963979 chr7:1858916 MAD1L1 0.45 7.15 0.36 5.33e-12 Bipolar disorder and schizophrenia; LIHC cis rs763014 0.966 rs15564 chr16:677854 G/T cg08989290 chr16:615782 NHLRC4 0.3 5.87 0.3 1.05e-8 Height; LIHC cis rs7309 0.935 rs6432674 chr2:162025322 G/T cg21211367 chr2:162094118 NA 0.37 5.73 0.3 2.25e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs916888 0.738 rs199515 chr17:44856641 C/G cg01570182 chr17:44337453 NA -0.93 -9.76 -0.47 5.04e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.45e-29 Menopause (age at onset); LIHC cis rs8044995 0.517 rs61593058 chr16:68384496 T/C cg05110241 chr16:68378359 PRMT7 -0.67 -8.19 -0.4 5.42e-15 Schizophrenia; LIHC cis rs10792665 0.724 rs10898068 chr11:82710889 A/C cg24227371 chr11:82718527 RAB30 -0.38 -9.3 -0.45 1.68e-18 Obesity-related traits; LIHC cis rs7927592 0.763 rs3740628 chr11:68381415 A/G cg20283391 chr11:68216788 NA -0.38 -6.04 -0.31 4.03e-9 Total body bone mineral density; LIHC cis rs250677 0.652 rs250670 chr5:148446646 G/T cg18129178 chr5:148520854 ABLIM3 -0.48 -7.51 -0.38 5.14e-13 Breast cancer; LIHC cis rs11628318 0.715 rs1815262 chr14:103056926 C/T cg01864069 chr14:103024347 NA -0.48 -7.35 -0.37 1.43e-12 Platelet count; LIHC cis rs2204008 0.659 rs4002655 chr12:38169881 T/G cg13010199 chr12:38710504 ALG10B 0.48 5.71 0.3 2.42e-8 Bladder cancer; LIHC cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 11.25 0.52 3.43e-25 Platelet count; LIHC cis rs4803468 1.000 rs4674 chr19:41930396 A/G cg09537434 chr19:41945824 ATP5SL -1.02 -20.37 -0.74 5.76e-61 Height; LIHC cis rs68170813 0.605 rs2299428 chr7:107134384 A/G cg02696742 chr7:106810147 HBP1 -0.54 -6.26 -0.32 1.16e-9 Coronary artery disease; LIHC cis rs10876993 0.890 rs10783844 chr12:58098425 A/C cg04478727 chr12:58166393 METTL1;FAM119B -0.42 -5.81 -0.3 1.41e-8 Celiac disease or Rheumatoid arthritis; LIHC cis rs60871478 1.000 rs4721124 chr7:823761 T/C cg04727924 chr7:799746 HEATR2 -0.58 -8.66 -0.42 1.92e-16 Cerebrospinal P-tau181p levels; LIHC cis rs7793919 0.691 rs4077986 chr7:4766676 A/G cg09789173 chr7:4769017 FOXK1 0.61 9.16 0.44 4.89e-18 Mosquito bite size; LIHC cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg08219700 chr8:58056026 NA 0.51 6.44 0.33 4.06e-10 Developmental language disorder (linguistic errors); LIHC cis rs950169 0.649 rs12905952 chr15:84691261 G/A cg17507749 chr15:85114479 UBE2QP1 0.67 6.39 0.33 5.38e-10 Schizophrenia; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg22903471 chr2:27725779 GCKR -0.5 -8.54 -0.42 4.55e-16 Total body bone mineral density; LIHC cis rs1395 0.778 rs17005956 chr2:27451099 C/T cg22903471 chr2:27725779 GCKR -0.41 -6.16 -0.32 2.07e-9 Blood metabolite levels; LIHC cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.02 0.31 4.58e-9 Menopause (age at onset); LIHC cis rs7927592 0.763 rs1193699 chr11:68249480 C/G cg01657329 chr11:68192670 LRP5 -0.47 -6.83 -0.35 3.91e-11 Total body bone mineral density; LIHC cis rs7662987 0.517 rs2851263 chr4:100030354 A/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs7659604 0.502 rs28435300 chr4:122709412 T/C cg19671926 chr4:122722719 EXOSC9 0.56 8.63 0.42 2.3e-16 Type 2 diabetes; LIHC cis rs4076764 1.000 rs7525643 chr1:163426283 G/A cg24596788 chr1:163392923 NA -0.22 -6.95 -0.35 1.88e-11 Motion sickness; LIHC trans rs11098499 0.691 rs9996644 chr4:120238877 G/T cg25214090 chr10:38739885 LOC399744 0.52 8.5 0.42 6.06e-16 Corneal astigmatism; LIHC cis rs79149102 0.579 rs7173218 chr15:75315328 A/G cg16226627 chr15:75307476 SCAMP5 0.54 9.71 0.46 7.62e-20 Lung cancer; LIHC cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7582180 0.614 rs1030901 chr2:101007314 G/A cg14675211 chr2:100938903 LONRF2 0.56 8.26 0.41 3.22e-15 Intelligence (multi-trait analysis); LIHC cis rs6542838 0.704 rs12474283 chr2:99527310 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -6.95 -0.35 1.82e-11 Fear of minor pain; LIHC cis rs1419980 0.730 rs12229550 chr12:7745968 T/C cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs11229555 0.645 rs11229445 chr11:58199458 G/A cg15696309 chr11:58395628 NA -0.67 -7.93 -0.39 3.15e-14 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7927771 1.000 rs7927771 chr11:47781306 A/G cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.39e-18 Subjective well-being; LIHC cis rs561341 0.714 rs7218466 chr17:30263314 A/G cg13647721 chr17:30228624 UTP6 0.67 6.68 0.34 9.74e-11 Hip circumference adjusted for BMI; LIHC cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg10802521 chr3:52805072 NEK4 -0.41 -6.8 -0.34 4.81e-11 Bipolar disorder; LIHC cis rs7617773 0.780 rs11710257 chr3:48373214 T/G cg11946769 chr3:48343235 NME6 0.92 11.74 0.54 5.69e-27 Coronary artery disease; LIHC cis rs2274273 0.648 rs58553156 chr14:55582694 T/A cg01864836 chr14:55583639 NA -0.38 -6.63 -0.34 1.28e-10 Protein biomarker; LIHC cis rs8044868 0.530 rs2550868 chr16:72066072 G/A cg16558253 chr16:72132732 DHX38 -0.37 -6.05 -0.31 3.83e-9 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg23131131 chr22:24373011 LOC391322 -0.66 -9.92 -0.47 1.46e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7107174 1.000 rs948662 chr11:77979829 A/G cg02023728 chr11:77925099 USP35 0.49 9.57 0.46 2.25e-19 Testicular germ cell tumor; LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs919433 0.588 rs11690163 chr2:198527507 A/T cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03602528 chr17:19266095 B9D1 -0.47 -6.15 -0.32 2.13e-9 Systolic blood pressure; LIHC cis rs17685 0.558 rs60787921 chr7:75792844 C/A cg04610667 chr7:75704037 NA -0.35 -6.21 -0.32 1.54e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10792665 0.575 rs5006164 chr11:82557595 T/C cg24227371 chr11:82718527 RAB30 -0.25 -6.0 -0.31 5.11e-9 Obesity-related traits; LIHC cis rs9814567 1.000 rs35718987 chr3:134272783 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2228479 0.717 rs12917681 chr16:89810941 C/A cg00800038 chr16:89945340 TCF25 -0.61 -9.42 -0.45 7.08e-19 Skin colour saturation; LIHC trans rs11098499 0.909 rs28555550 chr4:120211040 C/G cg25214090 chr10:38739885 LOC399744 0.51 7.76 0.39 9.62e-14 Corneal astigmatism; LIHC cis rs6701037 0.625 rs72719370 chr1:175128536 G/C cg00958927 chr1:175162553 KIAA0040 -0.4 -6.55 -0.33 2.08e-10 Alcohol dependence; LIHC cis rs826838 0.806 rs826873 chr12:39121305 G/A cg26384229 chr12:38710491 ALG10B -0.63 -9.31 -0.45 1.61e-18 Heart rate; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC cis rs8067354 0.958 rs8081468 chr17:57836924 A/G cg13753209 chr17:57696993 CLTC 0.58 8.76 0.43 9.51e-17 Hemoglobin concentration; LIHC cis rs17685 0.725 rs7795291 chr7:75725206 C/A cg04592579 chr7:75616294 TMEM120A 0.39 6.67 0.34 1.03e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs539514 0.637 rs2025354 chr13:76275577 T/C cg04757411 chr13:76259545 LMO7 -0.45 -7.98 -0.4 2.3e-14 Type 1 diabetes; LIHC cis rs4820539 1.000 rs885965 chr22:23461425 A/G cg21100191 chr22:23484243 RTDR1 0.87 15.36 0.64 7.61e-41 Bone mineral density; LIHC cis rs10751667 0.666 rs7395182 chr11:927553 A/C cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC cis rs4728302 0.838 rs10225605 chr7:133591676 G/A cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs1355223 1.000 rs11601205 chr11:34768479 C/T cg11058730 chr11:34937778 PDHX;APIP -0.48 -6.55 -0.33 2.05e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2302190 0.882 rs8067183 chr17:56462023 G/A cg12560992 chr17:57184187 TRIM37 0.65 8.2 0.41 4.87e-15 Vitamin D levels; LIHC cis rs523522 0.962 rs12371550 chr12:120987643 C/T cg12219531 chr12:120966889 COQ5 0.68 13.4 0.59 3.27e-33 High light scatter reticulocyte count; LIHC cis rs3789045 0.774 rs4252733 chr1:204516918 C/T cg17419461 chr1:204415978 PIK3C2B -0.41 -6.31 -0.32 8.76e-10 Educational attainment (college completion); LIHC cis rs3806843 0.676 rs2563304 chr5:140072057 C/T cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs78545713 1.000 rs78545713 chr6:26248840 A/G cg16070018 chr6:26224392 HIST1H3E 0.72 7.6 0.38 2.9e-13 Iron status biomarkers (total iron binding capacity); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11892836 chr11:64410564 NRXN2 0.4 6.09 0.31 2.98e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs68170813 0.596 rs76888321 chr7:106945926 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.87 -0.3 1.05e-8 Coronary artery disease; LIHC cis rs311392 0.902 rs411371 chr8:55092609 G/A cg11783602 chr8:55087084 NA -0.31 -6.19 -0.32 1.73e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs6570726 0.791 rs6570693 chr6:145910841 C/T cg23711669 chr6:146136114 FBXO30 0.7 11.65 0.53 1.22e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.790 rs9497424 chr6:146225271 C/A cg23711669 chr6:146136114 FBXO30 -0.61 -10.74 -0.5 2.16e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs2439831 1.000 rs28628574 chr15:43802038 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.69 9.15 0.44 5.42e-18 Lung cancer in ever smokers; LIHC cis rs3204270 0.530 rs57707013 chr17:79635281 C/T cg18367735 chr17:79674897 NA 0.64 7.48 0.37 6.34e-13 Dental caries; LIHC cis rs7927592 0.956 rs2510384 chr11:68391837 C/A cg20283391 chr11:68216788 NA -0.52 -7.77 -0.39 9.51e-14 Total body bone mineral density; LIHC cis rs3749237 0.595 rs1464566 chr3:49459376 T/C cg06212747 chr3:49208901 KLHDC8B 0.44 5.84 0.3 1.21e-8 Resting heart rate; LIHC cis rs9611565 0.918 rs2281333 chr22:41749630 T/C cg03806693 chr22:41940476 POLR3H -0.47 -6.06 -0.31 3.67e-9 Vitiligo; LIHC cis rs2303759 0.874 rs8108669 chr19:49845895 C/T cg24324837 chr19:49891574 CCDC155 0.39 6.22 0.32 1.43e-9 Multiple sclerosis; LIHC cis rs1577917 1.000 rs12205548 chr6:86759770 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -9.92 -0.47 1.55e-20 Response to antipsychotic treatment; LIHC cis rs8114671 0.869 rs1544047 chr20:33670753 T/C cg07148914 chr20:33460835 GGT7 -0.55 -8.3 -0.41 2.48e-15 Height; LIHC cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 9.61 0.46 1.59e-19 Mean platelet volume; LIHC cis rs7581030 0.518 rs7578166 chr2:71630041 A/C cg07678644 chr2:71558969 ZNF638 0.38 6.0 0.31 5.13e-9 Testicular germ cell tumor; LIHC cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.69 11.37 0.52 1.29e-25 Menarche (age at onset); LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg14671364 chr1:107599128 PRMT6 -0.54 -7.87 -0.39 4.72e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4845459 0.967 rs4085613 chr1:152550018 T/G cg20634798 chr1:152595351 LCE3A -0.32 -6.17 -0.32 1.91e-9 Psoriasis; LIHC cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg01788221 chr16:89496183 ANKRD11 -0.39 -6.2 -0.32 1.64e-9 Multiple myeloma (IgH translocation); LIHC cis rs1008375 0.966 rs4698638 chr4:17632988 G/C cg04450456 chr4:17643702 FAM184B 0.34 5.73 0.3 2.17e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs5769707 0.609 rs2007024 chr22:49988815 C/T cg01652190 chr22:50026171 C22orf34 -0.33 -7.47 -0.37 6.9e-13 Monocyte count;Monocyte percentage of white cells; LIHC trans rs1814175 0.527 rs7110797 chr11:49644096 T/C cg03929089 chr4:120376271 NA -0.68 -9.88 -0.47 2.07e-20 Height; LIHC cis rs6500602 0.963 rs7201012 chr16:4480682 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.41 0.33 4.94e-10 Schizophrenia; LIHC cis rs17270561 0.723 rs12192635 chr6:25880907 A/T cg17691542 chr6:26056736 HIST1H1C 0.8 9.47 0.46 4.59e-19 Iron status biomarkers; LIHC cis rs8114671 0.562 rs4911447 chr20:33479445 T/A cg07148914 chr20:33460835 GGT7 0.65 9.86 0.47 2.39e-20 Height; LIHC cis rs9309473 1.000 rs7576245 chr2:73829678 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.9 -0.35 2.46e-11 Metabolite levels; LIHC cis rs2075371 1.000 rs2505 chr7:133979552 C/T cg11752832 chr7:134001865 SLC35B4 0.5 7.53 0.38 4.66e-13 Mean platelet volume; LIHC cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg02359409 chr6:42947317 PEX6 -0.49 -6.99 -0.35 1.42e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs35883536 0.647 rs17402665 chr1:101046940 C/T cg14515779 chr1:101123966 NA 0.5 6.9 0.35 2.49e-11 Monocyte count; LIHC trans rs11098499 0.644 rs10009566 chr4:120558608 A/G cg25214090 chr10:38739885 LOC399744 0.5 8.04 0.4 1.51e-14 Corneal astigmatism; LIHC cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg16262614 chr3:133464971 TF 0.27 6.07 0.31 3.45e-9 Iron status biomarkers; LIHC cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg03264133 chr6:25882463 NA -0.72 -8.99 -0.44 1.68e-17 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg20607798 chr8:58055168 NA 0.73 8.42 0.41 1.05e-15 Developmental language disorder (linguistic errors); LIHC cis rs3812111 0.609 rs1204777 chr6:116494940 A/G cg08036074 chr6:116424633 NT5DC1 -0.46 -7.55 -0.38 3.89e-13 Age-related macular degeneration; LIHC cis rs172166 0.694 rs203876 chr6:28046673 T/C cg16479474 chr6:28041457 NA 0.4 6.65 0.34 1.18e-10 Cardiac Troponin-T levels; LIHC cis rs9640161 0.742 rs2108854 chr7:150017408 C/T cg17279839 chr7:150038598 RARRES2 -0.5 -10.68 -0.5 3.69e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs5769765 0.862 rs9616380 chr22:50312225 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs4759375 0.920 rs7972811 chr12:123820780 G/T cg00376283 chr12:123451042 ABCB9 0.5 6.44 0.33 4.06e-10 HDL cholesterol; LIHC cis rs6500602 1.000 rs6500602 chr16:4497451 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.42 5.8 0.3 1.48e-8 Schizophrenia; LIHC cis rs7582180 0.700 rs11685293 chr2:100976502 A/C cg14675211 chr2:100938903 LONRF2 0.52 7.88 0.39 4.51e-14 Intelligence (multi-trait analysis); LIHC cis rs2067615 0.599 rs12369214 chr12:107198611 G/A cg15890332 chr12:107067104 RFX4 0.26 6.2 0.32 1.59e-9 Heart rate; LIHC cis rs12540874 0.542 rs4947582 chr7:50566090 C/T cg14593290 chr7:50529359 DDC -0.35 -6.12 -0.31 2.57e-9 Systemic sclerosis; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg24068859 chr3:194392930 LSG1 0.52 6.15 0.32 2.14e-9 Glycated hemoglobin levels; LIHC cis rs7945718 0.870 rs3890065 chr11:12758767 C/G cg25843174 chr11:12811716 TEAD1 0.33 7.39 0.37 1.12e-12 Educational attainment (years of education); LIHC trans rs36715 1.000 rs36702 chr5:127552723 A/T cg16011800 chr17:1958478 HIC1 -0.4 -6.05 -0.31 3.75e-9 Breast cancer; LIHC cis rs7116495 0.609 rs73543640 chr11:71834374 G/T cg10381502 chr11:71823885 C11orf51 1.06 9.3 0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC trans rs916888 0.821 rs199513 chr17:44856932 A/G cg16836995 chr17:43662488 NA 0.6 6.26 0.32 1.17e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2228479 0.850 rs17226519 chr16:89839854 T/C cg00800038 chr16:89945340 TCF25 -0.62 -9.35 -0.45 1.2e-18 Skin colour saturation; LIHC cis rs11212260 0.655 rs79059631 chr11:107326042 T/A cg25435332 chr11:107328525 CWF19L2 0.82 8.43 0.41 9.83e-16 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18789337 chr6:114180353 MARCKS 0.47 7.07 0.36 8.78e-12 Cognitive function; LIHC cis rs2204008 0.837 rs55962152 chr12:38234281 G/A cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC cis rs2845885 0.744 rs3802932 chr11:63988045 G/A cg19006947 chr11:64034861 PLCB3 -0.61 -8.87 -0.43 4.07e-17 Body mass index; LIHC trans rs3780486 0.505 rs10813959 chr9:33166234 C/T cg04842962 chr6:43655489 MRPS18A -0.79 -14.97 -0.63 2.62e-39 IgG glycosylation; LIHC cis rs7264396 0.747 rs73283043 chr20:34383863 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -11.09 -0.51 1.32e-24 Total cholesterol levels; LIHC cis rs253664 0.898 rs1199347 chr3:138083361 T/C cg25188949 chr3:137893707 DBR1 -0.57 -5.77 -0.3 1.8e-8 Body mass index; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg10150615 chr22:24372951 LOC391322 -0.46 -6.35 -0.32 6.85e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs875971 1.000 rs9986696 chr7:65704576 C/A cg18876405 chr7:65276391 NA -0.38 -6.88 -0.35 2.82e-11 Aortic root size; LIHC trans rs10744955 0.533 rs9707844 chr15:50444400 A/G cg02452418 chr19:39056126 RYR1 0.55 6.04 0.31 4.08e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg09323728 chr8:95962352 TP53INP1 -0.27 -6.04 -0.31 4.05e-9 Type 2 diabetes; LIHC trans rs11039798 0.764 rs1121450 chr11:48897476 C/T cg15704280 chr7:45808275 SEPT13 0.61 6.29 0.32 9.52e-10 Axial length; LIHC cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg16414030 chr3:133502952 NA -0.41 -6.4 -0.33 5.08e-10 Iron status biomarkers; LIHC cis rs1348850 0.914 rs7573763 chr2:178249808 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 13.96 0.6 2.22e-35 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg12252866 chr3:50263686 NA -0.4 -6.42 -0.33 4.6e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs6840360 0.726 rs6816292 chr4:152730543 C/T cg22705602 chr4:152727874 NA 0.31 6.53 0.33 2.34e-10 Intelligence (multi-trait analysis); LIHC cis rs3820068 0.822 rs2901964 chr1:15792426 C/G cg17385448 chr1:15911702 AGMAT 0.37 6.6 0.34 1.55e-10 Systolic blood pressure; LIHC cis rs17253792 0.822 rs8013714 chr14:56172286 T/C cg01858014 chr14:56050164 KTN1 -0.63 -6.99 -0.35 1.42e-11 Putamen volume; LIHC cis rs801193 1.000 rs2659915 chr7:66153101 A/G cg14393609 chr7:65229607 NA 0.37 5.86 0.3 1.07e-8 Aortic root size; LIHC cis rs908922 0.676 rs1053590 chr1:152488428 T/C cg20991723 chr1:152506922 NA 0.5 8.49 0.42 6.21e-16 Hair morphology; LIHC cis rs2279817 0.731 rs11203434 chr1:18010189 G/C cg21791023 chr1:18019539 ARHGEF10L -0.41 -5.86 -0.3 1.08e-8 Neuroticism; LIHC cis rs892961 0.932 rs3987887 chr17:75414862 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.45 0.37 7.9e-13 Airflow obstruction; LIHC cis rs2115630 0.641 rs11073613 chr15:85185893 G/A cg12501888 chr15:85177176 SCAND2 -0.44 -6.49 -0.33 3.05e-10 P wave terminal force; LIHC trans rs637571 0.522 rs1151512 chr11:65757533 G/A cg17712092 chr4:129076599 LARP1B 0.74 13.11 0.58 4.34e-32 Eosinophil percentage of white cells; LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg25894440 chr7:65020034 NA -0.41 -6.61 -0.34 1.5e-10 Calcium levels; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg00091569 chr3:40428383 ENTPD3 0.39 6.54 0.33 2.23e-10 Renal cell carcinoma; LIHC cis rs17021463 0.807 rs6847989 chr4:95277099 A/C cg11021082 chr4:95130006 SMARCAD1 0.35 6.2 0.32 1.63e-9 Testicular germ cell tumor; LIHC cis rs10911363 0.615 rs12024309 chr1:183419981 A/G cg09173681 chr1:183549694 NCF2 -0.54 -9.51 -0.46 3.55e-19 Systemic lupus erythematosus; LIHC cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg03517284 chr6:25882590 NA -0.88 -12.77 -0.57 8.48e-31 Blood metabolite levels; LIHC cis rs1775715 0.870 rs7095322 chr10:32248491 C/T cg14930904 chr10:32216787 ARHGAP12 -0.37 -6.71 -0.34 8.1e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs7208859 0.623 rs9911173 chr17:29154750 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.01 0.4 1.79e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs796364 0.715 rs78988795 chr2:201095739 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.64 -5.97 -0.31 5.8e-9 Schizophrenia; LIHC cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.55 8.29 0.41 2.64e-15 Height; LIHC trans rs1814175 0.817 rs4405313 chr11:50013636 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC cis rs3096299 0.679 rs3096322 chr16:89441123 A/G cg02187348 chr16:89574699 SPG7 -0.41 -6.0 -0.31 5.03e-9 Multiple myeloma (IgH translocation); LIHC cis rs853679 0.517 rs9393884 chr6:28046789 A/G cg16479474 chr6:28041457 NA 0.46 6.76 0.34 6.14e-11 Depression; LIHC cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs16858210 0.647 rs67397446 chr3:183618143 C/T cg25686905 chr3:183603175 PARL -0.4 -6.24 -0.32 1.31e-9 Menopause (age at onset); LIHC cis rs9896052 0.649 rs6501801 chr17:73447030 A/G cg25649188 chr17:73499917 CASKIN2 -0.41 -6.45 -0.33 3.91e-10 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs9921222 0.565 rs1805105 chr16:396264 A/G cg00101154 chr16:420108 MRPL28 -0.43 -6.34 -0.32 7.16e-10 Bone mineral density (spine);Bone mineral density; LIHC cis rs1816752 0.875 rs17384871 chr13:25059097 T/C cg22771759 chr13:24902376 NA 0.32 6.66 0.34 1.06e-10 Obesity-related traits; LIHC cis rs80282103 0.867 rs80254477 chr10:1077387 T/G cg18964960 chr10:1102726 WDR37 0.67 6.37 0.33 5.99e-10 Glomerular filtration rate (creatinine); LIHC cis rs6840360 0.571 rs11932059 chr4:152524496 G/A cg22705602 chr4:152727874 NA -0.32 -6.22 -0.32 1.43e-9 Intelligence (multi-trait analysis); LIHC cis rs243505 0.559 rs734003 chr7:148505498 T/G cg09806900 chr7:148480153 CUL1 0.41 6.09 0.31 3e-9 Inflammatory bowel disease;Crohn's disease; LIHC trans rs7615952 0.551 rs12695470 chr3:125635718 C/A cg07211511 chr3:129823064 LOC729375 -0.86 -10.47 -0.49 2.03e-22 Blood pressure (smoking interaction); LIHC cis rs10504229 0.681 rs11779172 chr8:58045538 A/G cg20607798 chr8:58055168 NA 0.47 6.42 0.33 4.58e-10 Developmental language disorder (linguistic errors); LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg01032570 chr8:22224534 SLC39A14 -0.56 -6.47 -0.33 3.43e-10 Obesity-related traits; LIHC cis rs798554 0.679 rs1636250 chr7:2884433 T/C cg04166393 chr7:2884313 GNA12 0.53 8.36 0.41 1.64e-15 Height; LIHC cis rs57504626 1 rs57504626 chr19:19720399 C/T cg03709012 chr19:19516395 GATAD2A 0.84 7.78 0.39 8.52e-14 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; LIHC cis rs1577917 0.958 rs1591438 chr6:86525214 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -11.03 -0.51 2.07e-24 Response to antipsychotic treatment; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22806587 chr15:75871813 PTPN9 0.47 6.93 0.35 2.09e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1538970 1.000 rs2050884 chr1:45830824 A/G cg24296786 chr1:45957014 TESK2 -0.5 -7.5 -0.38 5.41e-13 Platelet count; LIHC cis rs2976388 0.578 rs3758081 chr8:143824373 A/G cg24634471 chr8:143751801 JRK -0.42 -5.86 -0.3 1.1e-8 Urinary tract infection frequency; LIHC cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg20607798 chr8:58055168 NA -0.58 -6.87 -0.35 3.06e-11 Developmental language disorder (linguistic errors); LIHC cis rs9522267 0.535 rs4773393 chr13:112229755 A/G cg10483660 chr13:112241077 NA -0.22 -5.95 -0.31 6.75e-9 Hepatitis; LIHC cis rs2070433 0.948 rs2839304 chr21:47952650 C/G cg12379764 chr21:47803548 PCNT -0.67 -9.82 -0.47 3.24e-20 Lymphocyte counts; LIHC cis rs644799 1.000 rs11021319 chr11:95523123 C/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.82 0.3 1.39e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10464366 0.544 rs2280667 chr7:39172228 A/C cg10621924 chr7:39171070 POU6F2 0.41 6.28 0.32 1.03e-9 IgG glycosylation; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg03191532 chr2:237032664 AGAP1 0.38 6.44 0.33 3.97e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs10242455 0.702 rs45461000 chr7:99052710 A/G cg09045935 chr12:6379348 NA 0.84 6.91 0.35 2.41e-11 Blood metabolite levels; LIHC cis rs11229555 1.000 rs8373 chr11:58378424 A/G cg15696309 chr11:58395628 NA -0.73 -8.95 -0.44 2.24e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs826838 1.000 rs34254519 chr12:39041235 G/A cg13010199 chr12:38710504 ALG10B 0.55 6.8 0.34 4.81e-11 Heart rate; LIHC cis rs6665290 0.904 rs10916075 chr1:227184074 G/A cg10327440 chr1:227177885 CDC42BPA -1.18 -26.55 -0.82 4.16e-85 Myeloid white cell count; LIHC cis rs2153535 0.580 rs6905237 chr6:8471790 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs12995491 0.933 rs34366691 chr2:88537451 G/A cg04511125 chr2:88470314 THNSL2 -0.42 -6.43 -0.33 4.23e-10 Response to metformin (IC50); LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg01238044 chr22:24384105 GSTT1 -0.73 -10.85 -0.51 8.88e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg24675658 chr1:53192096 ZYG11B 0.63 10.23 0.48 1.29e-21 Monocyte count; LIHC cis rs8062405 0.723 rs12445744 chr16:28588395 A/C cg00204512 chr16:28754710 NA 0.4 6.82 0.35 4.26e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7937890 0.507 rs4463820 chr11:14556342 A/G cg02886208 chr11:14281011 SPON1 -0.44 -6.14 -0.32 2.3e-9 Mitochondrial DNA levels; LIHC cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg13409248 chr3:40428643 ENTPD3 -0.38 -6.28 -0.32 1.05e-9 Renal cell carcinoma; LIHC cis rs11190604 1.000 rs6584383 chr10:102303065 C/G cg07080220 chr10:102295463 HIF1AN 0.52 7.34 0.37 1.6e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs11711311 0.747 rs9882193 chr3:113349451 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.33 6.07 0.31 3.31e-9 IgG glycosylation; LIHC cis rs6088580 0.634 rs6141471 chr20:33006730 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.34 -0.58 5.73e-33 Glomerular filtration rate (creatinine); LIHC cis rs72634258 0.554 rs4908694 chr1:7850898 C/T cg26816564 chr1:7831052 VAMP3 0.62 5.9 0.3 8.54e-9 Inflammatory bowel disease; LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg12034118 chr1:209979487 IRF6 0.37 5.82 0.3 1.38e-8 Cleft lip with or without cleft palate; LIHC cis rs10464366 0.544 rs4723824 chr7:39153698 T/C cg20302533 chr7:39170763 POU6F2 0.38 6.79 0.34 5.08e-11 IgG glycosylation; LIHC cis rs8072100 0.840 rs4968319 chr17:45464967 A/G cg25173405 chr17:45401733 C17orf57 -0.43 -6.0 -0.31 4.91e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12074084 chr1:45140087 C1orf228;TMEM53 0.42 6.05 0.31 3.7e-9 Lung function (FEV1/FVC); LIHC cis rs7666738 0.830 rs3852123 chr4:98697586 A/G cg05340658 chr4:99064831 C4orf37 0.64 11.05 0.51 1.8e-24 Colonoscopy-negative controls vs population controls; LIHC trans rs208515 0.525 rs12193560 chr6:66690457 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.86 0.43 4.37e-17 Exhaled nitric oxide levels; LIHC trans rs4824093 0.610 rs28473584 chr22:50315413 C/T cg09872104 chr7:134855509 C7orf49 -0.75 -6.04 -0.31 4.09e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs80282103 0.867 rs11250242 chr10:1100064 A/C cg08668510 chr10:1095578 IDI1 -0.71 -7.06 -0.36 9.36e-12 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg21448741 chr8:58168803 NA 0.36 6.72 0.34 7.69e-11 Developmental language disorder (linguistic errors); LIHC cis rs4908768 0.579 rs7520572 chr1:8871690 G/A cg20416874 chr1:8611966 RERE 0.44 6.57 0.33 1.88e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs700651 0.789 rs1813106 chr2:198880589 A/G cg00792783 chr2:198669748 PLCL1 0.4 5.92 0.3 8.03e-9 Intracranial aneurysm; LIHC cis rs9911578 0.967 rs8182277 chr17:57144367 C/T cg12560992 chr17:57184187 TRIM37 0.97 17.95 0.7 3.2e-51 Intelligence (multi-trait analysis); LIHC cis rs7937890 0.631 rs7118886 chr11:14427517 T/C cg02251663 chr11:14281053 SPON1 -0.44 -5.82 -0.3 1.34e-8 Mitochondrial DNA levels; LIHC cis rs9790314 0.540 rs9844862 chr3:161076188 G/A cg03342759 chr3:160939853 NMD3 -0.43 -6.25 -0.32 1.23e-9 Morning vs. evening chronotype; LIHC cis rs250677 0.641 rs2915807 chr5:148450950 A/G cg12140854 chr5:148520817 ABLIM3 -0.52 -5.97 -0.31 5.92e-9 Breast cancer; LIHC cis rs2243480 1.000 rs67536397 chr7:65947917 G/A cg07424592 chr7:64974309 NA 0.81 9.12 0.44 6.81e-18 Diabetic kidney disease; LIHC cis rs4332037 0.805 rs10278591 chr7:1921362 A/G cg23422044 chr7:1970798 MAD1L1 0.64 10.23 0.48 1.29e-21 Bipolar disorder; LIHC cis rs9486715 1.000 rs9398148 chr6:97063555 A/G cg18709589 chr6:96969512 KIAA0776 -0.35 -6.11 -0.31 2.75e-9 Headache; LIHC cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.11e-8 Bipolar disorder; LIHC cis rs7617773 0.817 rs9818937 chr3:48325281 G/A cg11946769 chr3:48343235 NME6 0.87 11.38 0.52 1.15e-25 Coronary artery disease; LIHC cis rs8067354 0.645 rs9910518 chr17:57812067 T/C cg13753209 chr17:57696993 CLTC 0.73 11.52 0.53 3.5e-26 Hemoglobin concentration; LIHC cis rs11724804 0.532 rs7657611 chr4:880558 G/C cg20814179 chr4:940893 TMEM175 0.43 6.04 0.31 3.98e-9 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.753 rs7804598 chr7:75702578 C/T cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.89e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2744203 1.000 rs72610882 chr6:104638716 A/G cg27088726 chr16:83171155 CDH13 -0.46 -6.06 -0.31 3.7e-9 IgG glycosylation; LIHC cis rs17152411 0.895 rs7094381 chr10:126585848 G/A cg07906193 chr10:126599966 NA 0.44 6.96 0.35 1.78e-11 Height; LIHC cis rs12824058 0.831 rs11608406 chr12:130805866 G/C cg26677194 chr12:130822605 PIWIL1 0.5 6.58 0.34 1.77e-10 Menopause (age at onset); LIHC cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg11645453 chr3:52864694 ITIH4 0.22 6.04 0.31 3.96e-9 Bipolar disorder; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg18548523 chr11:67260961 PITPNM1 0.43 6.4 0.33 5.03e-10 Bilirubin levels; LIHC cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg07061783 chr6:25882402 NA -0.52 -6.4 -0.33 4.99e-10 Intelligence (multi-trait analysis); LIHC cis rs9303280 0.901 rs8067378 chr17:38051348 A/G cg11212589 chr17:38028394 ZPBP2 0.36 7.37 0.37 1.32e-12 Self-reported allergy; LIHC cis rs7584330 0.657 rs10202599 chr2:238352465 A/C cg14458575 chr2:238380390 NA 0.42 6.21 0.32 1.53e-9 Prostate cancer; LIHC cis rs6570726 0.577 rs406868 chr6:145809983 C/T cg05347473 chr6:146136440 FBXO30 0.45 6.81 0.35 4.36e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.601 rs9505451 chr6:8469950 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg01777103 chr8:145550585 DGAT1 0.38 6.06 0.31 3.5e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs6565180 0.783 rs9888967 chr16:30407979 G/C cg17640201 chr16:30407289 ZNF48 0.81 13.9 0.6 3.88e-35 Tonsillectomy; LIHC cis rs801193 0.569 rs6951302 chr7:66132512 T/C cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.69 -0.34 9.38e-11 Total body bone mineral density; LIHC cis rs703842 1.000 rs1875124 chr12:58196802 A/G cg18357645 chr12:58087776 OS9 -0.45 -6.98 -0.35 1.49e-11 Multiple sclerosis; LIHC cis rs7927592 0.546 rs638076 chr11:68202580 A/G cg01657329 chr11:68192670 LRP5 -0.54 -8.07 -0.4 1.2e-14 Total body bone mineral density; LIHC trans rs1728785 1.000 rs1364109 chr16:68595505 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.5 0.33 2.82e-10 Ulcerative colitis; LIHC cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg01788221 chr16:89496183 ANKRD11 -0.38 -5.86 -0.3 1.1e-8 Multiple myeloma (IgH translocation); LIHC cis rs6545883 0.826 rs1186697 chr2:61661417 G/A cg15711740 chr2:61764176 XPO1 -0.44 -6.15 -0.32 2.21e-9 Tuberculosis; LIHC cis rs986417 0.901 rs1061108 chr14:60978071 C/G cg27398547 chr14:60952738 C14orf39 0.74 8.32 0.41 2.19e-15 Gut microbiota (bacterial taxa); LIHC cis rs6582630 0.502 rs1915395 chr12:38420726 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.81 0.5 1.27e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg16132339 chr22:24313637 DDTL;DDT -0.73 -13.97 -0.6 2.01e-35 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs10411161 1.000 rs8111316 chr19:52369069 A/C cg22319618 chr22:45562946 NUP50 -0.53 -7.14 -0.36 5.77e-12 Breast cancer; LIHC cis rs7927771 0.965 rs35985502 chr11:47847428 G/A cg20307385 chr11:47447363 PSMC3 -0.44 -5.74 -0.3 2.04e-8 Subjective well-being; LIHC cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg18404041 chr3:52824283 ITIH1 0.68 11.5 0.53 4.29e-26 Bipolar disorder; LIHC cis rs748404 0.631 rs2467745 chr15:43722742 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.11e-13 Lung cancer; LIHC cis rs921968 0.643 rs492400 chr2:219349752 C/T cg02985541 chr2:219472218 PLCD4 0.46 8.73 0.43 1.18e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs1065656 0.553 rs344357 chr16:1836255 C/G cg07870479 chr16:1813987 MAPK8IP3 0.45 6.24 0.32 1.31e-9 Insulin-like growth factors; LIHC cis rs1707322 0.963 rs4508055 chr1:46257731 A/T cg06784218 chr1:46089804 CCDC17 0.39 6.86 0.35 3.19e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6960043 0.738 rs12540947 chr7:15059326 T/C cg19272540 chr7:15055459 NA 0.28 7.39 0.37 1.15e-12 Type 2 diabetes; LIHC cis rs2842992 0.958 rs2758318 chr6:160069637 C/G cg11366901 chr6:160182831 ACAT2 0.89 13.85 0.6 6.12e-35 Age-related macular degeneration (geographic atrophy); LIHC trans rs526821 0.595 rs517627 chr11:55356489 C/T cg15704280 chr7:45808275 SEPT13 -0.52 -7.8 -0.39 7.35e-14 Pediatric bone mineral density (spine); LIHC cis rs1670533 1.000 rs6812596 chr4:1069866 A/G cg27284194 chr4:1044797 NA 0.6 8.84 0.43 5.24e-17 Recombination rate (females); LIHC cis rs1707322 1.000 rs6675222 chr1:46326576 G/T cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg12496599 chr19:3199014 NCLN 0.4 6.23 0.32 1.38e-9 Bilirubin levels; LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs733592 0.524 rs10875744 chr12:48498440 G/C cg21466736 chr12:48725269 NA -0.34 -5.94 -0.31 6.92e-9 Plateletcrit; LIHC cis rs11969893 0.649 rs9485415 chr6:101279459 C/T cg12253828 chr6:101329408 ASCC3 0.93 11.79 0.54 3.65e-27 Economic and political preferences (immigration/crime); LIHC cis rs7582720 1.000 rs75324925 chr2:203698300 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs916888 0.821 rs199506 chr17:44859031 A/G cg16836995 chr17:43662488 NA 0.69 7.04 0.36 1.06e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7674212 0.541 rs4699050 chr4:104114297 A/G cg16532752 chr4:104119610 CENPE -0.42 -6.54 -0.33 2.23e-10 Type 2 diabetes; LIHC cis rs9473924 1.000 rs9463656 chr6:50859655 A/G cg14470998 chr6:50812995 TFAP2B 0.49 7.33 0.37 1.7e-12 Body mass index; LIHC cis rs208515 0.525 rs12204452 chr6:66680325 C/T cg07460842 chr6:66804631 NA 0.77 8.85 0.43 4.91e-17 Exhaled nitric oxide levels; LIHC cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2710642 0.861 rs2710644 chr2:63248968 A/C cg17519650 chr2:63277830 OTX1 0.62 9.2 0.45 3.73e-18 LDL cholesterol levels;LDL cholesterol; LIHC cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.931 rs4934720 chr10:35376800 T/C cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9902453 0.838 rs3110495 chr17:27978455 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -12.06 -0.55 3.69e-28 Coffee consumption (cups per day); LIHC cis rs10838687 0.736 rs11039144 chr11:47264044 G/A cg26139080 chr11:47293733 MADD -0.41 -5.73 -0.3 2.2e-8 Proinsulin levels; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs10751667 0.666 rs6597962 chr11:976351 C/T cg10932868 chr11:921992 NA 0.4 7.54 0.38 4.4e-13 Alzheimer's disease (late onset); LIHC cis rs1003719 0.699 rs1015549 chr21:38448880 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC trans rs7246657 1.000 rs8110011 chr19:37745813 G/T cg10208301 chr11:6592745 DNHD1 0.46 6.19 0.32 1.7e-9 Coronary artery calcification; LIHC cis rs7909074 0.831 rs2065466 chr10:45384047 T/C cg05187965 chr10:45406764 TMEM72 -0.27 -6.81 -0.35 4.28e-11 Mean corpuscular volume; LIHC cis rs921968 0.643 rs559722 chr2:219398159 A/G cg17980119 chr2:219472607 PLCD4 0.35 6.02 0.31 4.62e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs8017423 0.904 rs11622257 chr14:90715014 C/T cg14092571 chr14:90743983 NA 0.4 6.32 0.32 8.18e-10 Mortality in heart failure; LIHC cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg12756686 chr19:29218302 NA 0.44 6.83 0.35 3.94e-11 Methadone dose in opioid dependence; LIHC cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.22 0.36 3.39e-12 Bipolar disorder; LIHC cis rs1506636 1.000 rs644958 chr7:123400873 C/T cg03229431 chr7:123269106 ASB15 0.61 12.19 0.55 1.23e-28 Plateletcrit;Platelet count; LIHC cis rs16866061 0.515 rs13020268 chr2:225437923 C/T cg22509189 chr2:225307070 NA -0.5 -7.41 -0.37 1.02e-12 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs2243480 1.000 rs34933526 chr7:65383199 A/G cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00232805 chr2:97779565 ANKRD36 0.44 6.67 0.34 1e-10 Cognitive function; LIHC cis rs17685 0.672 rs6465011 chr7:75811297 T/C cg16684958 chr7:75615977 POR 0.49 8.29 0.41 2.54e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg09367891 chr1:107599246 PRMT6 -0.67 -10.74 -0.5 2.28e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs60871478 1.000 rs62432242 chr7:797715 G/A cg27478167 chr7:817139 HEATR2 -0.41 -5.86 -0.3 1.07e-8 Cerebrospinal P-tau181p levels; LIHC cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg13047869 chr3:10149882 C3orf24 0.51 6.63 0.34 1.3100000000000001e-10 Alzheimer's disease; LIHC cis rs8016982 0.657 rs8021125 chr14:81704787 C/T cg01989461 chr14:81687754 GTF2A1 -0.64 -12.8 -0.57 6.69e-31 Schizophrenia; LIHC cis rs763121 0.819 rs5750658 chr22:39060917 C/T cg14440974 chr22:39074834 NA -0.43 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC cis rs8077889 0.917 rs72836556 chr17:41911824 G/T cg26893861 chr17:41843967 DUSP3 1.0 11.14 0.52 8.48e-25 Triglycerides; LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg02475777 chr4:1388615 CRIPAK 0.39 6.02 0.31 4.43e-9 Obesity-related traits; LIHC cis rs8141529 0.509 rs12628211 chr22:29239250 T/C cg02153584 chr22:29168773 CCDC117 0.53 7.86 0.39 4.95e-14 Lymphocyte counts; LIHC cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg22907277 chr7:1156413 C7orf50 0.57 8.68 0.43 1.59e-16 Longevity;Endometriosis; LIHC cis rs116095464 0.764 rs10069197 chr5:230822 G/C cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs7216064 1.000 rs62085992 chr17:65923083 T/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.33 -0.45 1.41e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6598955 0.724 rs10902737 chr1:26635716 G/A cg04990556 chr1:26633338 UBXN11 -0.61 -9.8 -0.47 3.79e-20 Obesity-related traits; LIHC cis rs6545883 0.894 rs2463102 chr2:61571295 G/C cg14146966 chr2:61757674 XPO1 -0.44 -7.37 -0.37 1.31e-12 Tuberculosis; LIHC cis rs9902453 0.542 rs3809789 chr17:27955761 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 10.86 0.51 8.71e-24 Coffee consumption (cups per day); LIHC cis rs7100689 0.646 rs1572819 chr10:82112488 A/G cg01528321 chr10:82214614 TSPAN14 0.76 9.87 0.47 2.28e-20 Post bronchodilator FEV1; LIHC cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg23205692 chr1:25664452 TMEM50A 0.38 6.03 0.31 4.26e-9 Erythrocyte sedimentation rate; LIHC cis rs611744 0.967 rs678387 chr8:109242730 G/C cg18478394 chr8:109455254 TTC35 0.38 6.55 0.33 2.06e-10 Dupuytren's disease; LIHC cis rs12701220 0.522 rs1881116 chr7:1053958 C/T cg16145915 chr7:1198662 ZFAND2A -0.28 -5.97 -0.31 6.09e-9 Bronchopulmonary dysplasia; LIHC cis rs12478296 1.000 rs55758933 chr2:243040289 T/C cg18898632 chr2:242989856 NA -0.58 -7.84 -0.39 5.85e-14 Obesity-related traits; LIHC cis rs941408 1.000 rs2260416 chr19:2796355 G/A cg06609049 chr19:2785107 THOP1 0.54 9.52 0.46 3.15e-19 Total cholesterol levels; LIHC cis rs5769765 0.817 rs8142561 chr22:50291750 T/C cg26441486 chr22:50317300 CRELD2 0.36 6.38 0.33 5.73e-10 Schizophrenia; LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg26570765 chr4:1273065 NA 0.31 5.97 0.31 6.03e-9 Obesity-related traits; LIHC cis rs936229 0.861 rs7176022 chr15:75107880 G/T cg14664628 chr15:75095509 CSK 1.03 22.16 0.77 4.24e-68 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs12579753 0.913 rs7965664 chr12:82237340 G/T cg07988820 chr12:82153109 PPFIA2 -0.47 -5.71 -0.3 2.39e-8 Resting heart rate; LIHC trans rs11098499 0.535 rs7671759 chr4:120248094 A/C cg25214090 chr10:38739885 LOC399744 0.5 8.06 0.4 1.32e-14 Corneal astigmatism; LIHC cis rs1707322 1.000 rs6657720 chr1:46386269 G/A cg06784218 chr1:46089804 CCDC17 0.34 6.03 0.31 4.19e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17854409 1.000 rs6010770 chr20:61494225 G/T cg05147244 chr20:61493195 TCFL5 1.16 10.64 0.5 5.04e-23 Obesity-related traits; LIHC cis rs7584330 0.910 rs66509917 chr2:238395394 T/G cg14458575 chr2:238380390 NA 0.37 6.03 0.31 4.29e-9 Prostate cancer; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg07133347 chr1:107600762 PRMT6 0.46 6.77 0.34 5.61e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3849570 0.961 rs3849571 chr3:81777716 A/C cg07356753 chr3:81810745 GBE1 -0.63 -10.41 -0.49 3.07e-22 Waist circumference;Body mass index; LIHC cis rs4268898 0.717 rs2543662 chr2:24443271 G/T cg06627628 chr2:24431161 ITSN2 0.63 8.94 0.44 2.56e-17 Asthma; LIHC cis rs6951245 0.554 rs76243429 chr7:1152543 C/T cg22907277 chr7:1156413 C7orf50 0.81 7.65 0.38 2e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7216064 0.953 rs11868959 chr17:65840810 T/C cg12091567 chr17:66097778 LOC651250 -0.67 -9.38 -0.45 9.54e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2115630 0.645 rs3825878 chr15:85174755 C/T cg12501888 chr15:85177176 SCAND2 -0.46 -6.99 -0.35 1.49e-11 P wave terminal force; LIHC cis rs6089829 0.962 rs6011548 chr20:61666063 C/T cg03213289 chr20:61660250 NA 0.5 8.97 0.44 1.99e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs1059312 0.669 rs11059917 chr12:129287925 T/A cg09035930 chr12:129282057 SLC15A4 0.66 12.11 0.55 2.42e-28 Systemic lupus erythematosus; LIHC cis rs3960554 0.569 rs11973658 chr7:75882026 A/C cg01364799 chr7:75623366 TMEM120A -0.52 -7.5 -0.38 5.7e-13 Eotaxin levels; LIHC cis rs2153535 0.580 rs4960423 chr6:8477210 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs1395 0.634 rs62130713 chr2:27525661 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -5.94 -0.31 7.01e-9 Blood metabolite levels; LIHC cis rs116095464 0.558 rs7356696 chr5:284251 A/G cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs1005277 0.579 rs2474588 chr10:38420870 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.89 -0.3 9.44e-9 Extrinsic epigenetic age acceleration; LIHC cis rs11098499 0.754 rs1814813 chr4:120258207 G/T cg09307838 chr4:120376055 NA -0.64 -9.75 -0.47 5.57e-20 Corneal astigmatism; LIHC cis rs735860 0.712 rs9395855 chr6:53176765 G/T cg10236188 chr6:53219634 NA -0.42 -7.72 -0.39 1.32e-13 Glaucoma; LIHC cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg15691649 chr6:25882328 NA -0.47 -7.12 -0.36 6.4e-12 Blood metabolite levels; LIHC cis rs826838 1.000 rs1719830 chr12:39096992 T/G cg26384229 chr12:38710491 ALG10B -0.55 -8.34 -0.41 1.91e-15 Heart rate; LIHC trans rs1814175 0.559 rs1818892 chr11:49863084 C/A cg15704280 chr7:45808275 SEPT13 -0.95 -19.96 -0.73 2.55e-59 Height; LIHC cis rs637571 0.780 rs653914 chr11:65676516 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.48 7.59 0.38 3e-13 Eosinophil percentage of white cells; LIHC trans rs7618501 1.000 rs4855862 chr3:49748833 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs3741404 0.620 rs2236648 chr11:63964657 C/T cg18225595 chr11:63971243 STIP1 0.62 10.27 0.49 9.51e-22 Platelet count; LIHC cis rs4808199 0.948 rs2074301 chr19:19381715 G/A cg03709012 chr19:19516395 GATAD2A 0.98 15.57 0.64 1.09e-41 Nonalcoholic fatty liver disease; LIHC trans rs2727020 0.796 rs7131672 chr11:49274421 A/C cg18944383 chr4:111397179 ENPEP -0.32 -7.07 -0.36 8.91e-12 Coronary artery disease; LIHC cis rs1707322 0.721 rs10789468 chr1:46124558 A/G cg03146154 chr1:46216737 IPP 0.58 10.32 0.49 6.53e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4268898 0.662 rs56006260 chr2:24409903 A/G cg06627628 chr2:24431161 ITSN2 -0.69 -8.99 -0.44 1.74e-17 Asthma; LIHC cis rs2016586 0.929 rs4821440 chr22:36114274 T/C cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 7.96e-10 Body mass index; LIHC cis rs8141529 0.748 rs5762881 chr22:29289346 C/A cg15103426 chr22:29168792 CCDC117 0.58 9.41 0.45 7.54e-19 Lymphocyte counts; LIHC trans rs7615952 0.800 rs13086460 chr3:125646417 C/T cg07211511 chr3:129823064 LOC729375 -0.84 -10.43 -0.49 2.67e-22 Blood pressure (smoking interaction); LIHC cis rs6693567 0.565 rs11205371 chr1:150398510 A/G cg15654264 chr1:150340011 RPRD2 0.49 8.18 0.4 5.54e-15 Migraine; LIHC cis rs826838 0.967 rs11183514 chr12:38760744 A/T cg26384229 chr12:38710491 ALG10B 1.04 13.79 0.6 1.09e-34 Heart rate; LIHC cis rs7116495 1.000 rs585228 chr11:71773289 G/C cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs7772486 0.875 rs9322043 chr6:146352690 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.78 0.3 1.67e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs709400 1.000 rs7150141 chr14:104129352 G/A cg26031613 chr14:104095156 KLC1 0.99 13.72 0.6 1.91e-34 Body mass index; LIHC cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.81 0.3 1.42e-8 Menopause (age at onset); LIHC cis rs11018874 0.597 rs10765243 chr11:89855118 C/G cg04552319 chr11:89519481 NA -0.35 -5.94 -0.31 6.84e-9 White blood cell types; LIHC cis rs4631830 0.720 rs2843560 chr10:51512129 C/G cg20129853 chr10:51489980 NA 0.41 9.01 0.44 1.43e-17 Prostate-specific antigen levels; LIHC cis rs7312933 0.533 rs11181499 chr12:42818761 A/G cg17420585 chr12:42539391 GXYLT1 -0.35 -5.75 -0.3 1.98e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs916888 0.779 rs199528 chr17:44843136 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.72 6.71 0.34 8.05e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7119038 0.818 rs11217040 chr11:118680648 C/A cg19308663 chr11:118741387 NA 0.4 6.04 0.31 3.97e-9 Sjögren's syndrome; LIHC cis rs6835098 0.962 rs10014010 chr4:174083230 C/T cg27433088 chr4:174089019 GALNT7 0.38 6.93 0.35 2.07e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs4888262 0.545 rs12716768 chr16:74556486 A/G cg01733217 chr16:74700730 RFWD3 -0.69 -11.83 -0.54 2.66e-27 Testicular germ cell tumor; LIHC cis rs7599312 0.534 rs2128321 chr2:213405276 G/T cg16329650 chr2:213403929 ERBB4 0.58 7.22 0.36 3.35e-12 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12602486 1.000 rs12602486 chr17:42241929 T/G cg08193365 chr17:42277699 NA 1.05 7.39 0.37 1.16e-12 Glycated hemoglobin levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03898802 chr21:37617652 DOPEY2 -0.39 -6.16 -0.32 2.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs5758659 0.714 rs2284087 chr22:42485671 T/C cg19513890 chr22:42538836 CYP2D7P1 0.41 8.21 0.41 4.73e-15 Cognitive function; LIHC cis rs4689592 0.503 rs4689064 chr4:7055603 A/G cg02503808 chr4:7069936 GRPEL1 -0.76 -10.62 -0.5 5.88e-23 Monocyte percentage of white cells; LIHC cis rs6809651 0.524 rs79262908 chr3:185803594 C/T cg00760338 chr3:185826511 ETV5 -0.86 -12.76 -0.57 8.83e-31 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs11229555 0.609 rs7928676 chr11:58188022 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4407350 0.967 rs5765722 chr22:44921063 G/A cg26276947 chr22:44892394 LDOC1L 0.34 6.32 0.32 8.2e-10 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg12419862 chr22:24373484 LOC391322 -0.67 -9.92 -0.47 1.45e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs425277 0.606 rs262664 chr1:2083537 G/C cg03732007 chr1:2071316 PRKCZ 0.35 6.08 0.31 3.23e-9 Height; LIHC cis rs2549003 0.870 rs61175929 chr5:131821548 C/G cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg03874509 chr1:107600012 PRMT6 -0.75 -11.77 -0.54 4.47e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9534288 0.763 rs34175925 chr13:46611800 G/A cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs992157 0.775 rs1877714 chr2:219134928 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.8 -12.61 -0.56 3.3e-30 Colorectal cancer; LIHC cis rs12762955 0.528 rs10903358 chr10:1102386 G/A cg26597838 chr10:835615 NA 0.73 6.78 0.34 5.34e-11 Response to angiotensin II receptor blocker therapy; LIHC cis rs6952808 0.929 rs11761270 chr7:1923695 C/T cg20295408 chr7:1910781 MAD1L1 -0.51 -7.42 -0.37 9.53e-13 Bipolar disorder and schizophrenia; LIHC cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg08499158 chr17:42289980 UBTF -0.51 -8.41 -0.41 1.16e-15 Total body bone mineral density; LIHC cis rs8076336 1 rs8076336 chr17:18212614 A/C cg16794390 chr17:18148240 FLII 0.42 6.4 0.33 5.22e-10 Parental longevity (combined parental age at death); LIHC cis rs6782228 0.509 rs2811495 chr3:128359957 A/G cg16766828 chr3:128327626 NA -0.4 -6.34 -0.32 7.21e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs17253792 0.915 rs76957332 chr14:56195370 G/A cg01858014 chr14:56050164 KTN1 -0.74 -7.58 -0.38 3.18e-13 Putamen volume; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg02529035 chr2:220377885 ACCN4 -0.38 -6.1 -0.31 2.86e-9 Urinary tract infection frequency; LIHC cis rs6430585 0.528 rs309120 chr2:136708787 G/C cg07169764 chr2:136633963 MCM6 0.97 14.97 0.63 2.64e-39 Corneal structure; LIHC cis rs6546550 1.000 rs6546550 chr2:70038232 C/G cg02498382 chr2:70120550 SNRNP27 -0.42 -6.85 -0.35 3.38e-11 Prevalent atrial fibrillation; LIHC cis rs796364 0.806 rs6435040 chr2:200861161 T/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 7.49 0.38 5.77e-13 Schizophrenia; LIHC cis rs963731 0.649 rs10166801 chr2:39250771 C/T cg04010122 chr2:39346883 SOS1 -0.69 -6.03 -0.31 4.3e-9 Corticobasal degeneration; LIHC cis rs9896052 0.500 rs7406077 chr17:73450015 T/A cg25649188 chr17:73499917 CASKIN2 0.46 6.91 0.35 2.34e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs6424115 0.830 rs3003333 chr1:24194014 A/T cg04160030 chr1:24195659 FUCA1 0.37 5.84 0.3 1.2e-8 Immature fraction of reticulocytes; LIHC cis rs782590 0.721 rs782641 chr2:55929294 C/T cg18811423 chr2:55921094 PNPT1 0.98 15.32 0.64 1.03e-40 Metabolic syndrome; LIHC cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg07061783 chr6:25882402 NA -0.77 -8.98 -0.44 1.84e-17 Intelligence (multi-trait analysis); LIHC cis rs897984 0.553 rs2125293 chr16:30863875 T/C cg02466173 chr16:30829666 NA 0.47 7.03 0.36 1.11e-11 Dementia with Lewy bodies; LIHC cis rs7412746 0.563 rs3768013 chr1:150815411 G/A cg17724175 chr1:150552817 MCL1 0.44 8.75 0.43 9.58e-17 Melanoma; LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg11494091 chr17:61959527 GH2 0.44 7.99 0.4 2.02e-14 Prudent dietary pattern; LIHC cis rs62458065 0.713 rs921406 chr7:32486205 G/C cg06627557 chr7:32535165 LSM5;AVL9 -0.59 -5.71 -0.3 2.43e-8 Metabolite levels (HVA/MHPG ratio); LIHC cis rs12142240 0.698 rs6703374 chr1:46862332 C/G cg00530320 chr1:46809349 NSUN4 0.53 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC cis rs7677751 0.806 rs7689569 chr4:55096398 G/A cg17187183 chr4:55093834 PDGFRA 0.67 8.4 0.41 1.21e-15 Corneal astigmatism; LIHC cis rs875971 1.000 rs709595 chr7:65817333 G/C cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs2153535 0.580 rs7761937 chr6:8459434 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.32 0.41 2.19e-15 Motion sickness; LIHC cis rs10464366 0.560 rs11763728 chr7:39145862 C/T cg15212455 chr7:39170539 POU6F2 0.4 7.58 0.38 3.36e-13 IgG glycosylation; LIHC cis rs5769765 0.865 rs9616369 chr22:50304591 A/C cg26441486 chr22:50317300 CRELD2 0.36 6.42 0.33 4.48e-10 Schizophrenia; LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.71 -0.3 2.45e-8 Total body bone mineral density; LIHC cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg06634786 chr22:41940651 POLR3H -0.79 -8.66 -0.42 1.96e-16 Vitiligo; LIHC cis rs8062405 0.720 rs9926245 chr16:28555706 T/A cg00204512 chr16:28754710 NA 0.34 6.92 0.35 2.22e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1712517 0.844 rs4918003 chr10:105044157 C/T cg05636881 chr10:105038444 INA 0.45 7.13 0.36 5.88e-12 Migraine; LIHC cis rs4908760 0.827 rs2401138 chr1:8704059 C/G cg20416874 chr1:8611966 RERE 0.6 11.48 0.53 5.09e-26 Vitiligo; LIHC cis rs826838 0.967 rs7963716 chr12:38876090 C/T cg13010199 chr12:38710504 ALG10B 0.59 7.04 0.36 1.07e-11 Heart rate; LIHC cis rs9534288 0.699 rs2146885 chr13:46659853 A/G cg15192986 chr13:46630673 CPB2 -0.44 -6.35 -0.32 6.91e-10 Blood protein levels; LIHC trans rs983392 0.678 rs1426253 chr11:59981218 A/C cg17275991 chr19:58003312 ZNF419 0.43 6.16 0.32 2.09e-9 Alzheimer's disease (late onset); LIHC cis rs801193 0.636 rs2659895 chr7:66196471 C/A cg18876405 chr7:65276391 NA 0.34 6.21 0.32 1.53e-9 Aortic root size; LIHC trans rs4332037 0.851 rs73050128 chr7:1961882 C/A cg11693508 chr17:37793320 STARD3 0.73 7.54 0.38 4.13e-13 Bipolar disorder; LIHC cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg08888203 chr3:10149979 C3orf24 0.52 6.27 0.32 1.07e-9 Alzheimer's disease; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg06873352 chr17:61820015 STRADA 0.61 9.44 0.45 5.81e-19 Height; LIHC cis rs17253792 0.822 rs75399477 chr14:56174413 T/C cg01858014 chr14:56050164 KTN1 -0.77 -7.65 -0.38 2.04e-13 Putamen volume; LIHC cis rs72781680 0.898 rs72796396 chr2:24178154 G/A cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC trans rs62103177 0.565 rs473119 chr18:77849459 T/G cg05926928 chr17:57297772 GDPD1 -0.66 -6.86 -0.35 3.33e-11 Opioid sensitivity; LIHC cis rs7129220 0.512 rs1867137 chr11:10228809 G/A cg01453529 chr11:10209919 SBF2 -0.43 -7.88 -0.39 4.41e-14 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs11190604 1.000 rs1054399 chr10:102312565 C/T cg07080220 chr10:102295463 HIF1AN 0.51 7.07 0.36 9.01e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.51 7.23 0.36 3.22e-12 Lymphocyte counts; LIHC cis rs2236918 0.643 rs3121389 chr1:242020264 C/T cg17736920 chr1:242011382 EXO1 0.4 5.9 0.3 8.69e-9 Menopause (age at onset); LIHC cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.58 -5.9 -0.3 8.72e-9 Diastolic blood pressure; LIHC cis rs12971120 0.891 rs11151960 chr18:72177232 G/A cg26446133 chr18:72167187 CNDP2 -0.8 -14.35 -0.61 6.9e-37 Refractive error; LIHC cis rs9790314 0.779 rs1599376 chr3:160900533 C/G cg03342759 chr3:160939853 NMD3 -0.71 -8.69 -0.43 1.49e-16 Morning vs. evening chronotype; LIHC cis rs2243480 0.522 rs73150635 chr7:65972490 C/T cg07424592 chr7:64974309 NA 0.8 8.32 0.41 2.09e-15 Diabetic kidney disease; LIHC cis rs11588062 0.601 rs11579255 chr1:46806959 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.46 7.26 0.37 2.64e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3814244 0.540 rs2159064 chr12:68410906 A/G cg15249341 chr12:68405565 NA 0.31 6.32 0.32 7.95e-10 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg23978390 chr7:1156363 C7orf50 0.64 9.92 0.47 1.46e-20 Longevity;Endometriosis; LIHC cis rs17433710 0.543 rs10753585 chr1:162669006 C/T cg01063088 chr1:162760584 HSD17B7 0.41 5.97 0.31 5.92e-9 Dupuytren's disease; LIHC cis rs2153535 0.542 rs9393012 chr6:8439809 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.88 0.39 4.36e-14 Motion sickness; LIHC cis rs10508774 0.810 rs1987197 chr10:32830595 C/T cg01819863 chr10:32635814 EPC1 0.6 5.78 0.3 1.66e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9457247 0.624 rs17524252 chr6:167466978 T/G cg12798992 chr6:167411361 FGFR1OP 0.45 6.75 0.34 6.53e-11 Crohn's disease; LIHC cis rs17125944 0.686 rs7141335 chr14:53336934 C/T cg00686598 chr14:53173677 PSMC6 -0.8 -9.28 -0.45 1.93e-18 Alzheimer's disease (late onset); LIHC cis rs1577917 0.958 rs12192546 chr6:86476484 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.64 11.18 0.52 6.16e-25 Response to antipsychotic treatment; LIHC cis rs34779708 0.733 rs60616028 chr10:35543802 G/A cg03585969 chr10:35415529 CREM 0.73 10.15 0.48 2.52e-21 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11761441 1.000 rs12718067 chr7:82873 T/C cg13828236 chr7:80970 NA 0.29 7.06 0.36 9.42e-12 Alzheimer's disease in APOE e4- carriers; LIHC cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg20607798 chr8:58055168 NA 0.6 7.16 0.36 4.89e-12 Developmental language disorder (linguistic errors); LIHC trans rs6600671 1.000 rs7532615 chr1:121172840 G/T cg09829573 chr1:144692074 NBPF9 0.45 8.33 0.41 2.04e-15 Hip geometry; LIHC cis rs7223966 1.000 rs2874121 chr17:61731024 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.65 0.34 1.17e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg10360323 chr17:41437877 NA 0.4 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg05368731 chr17:41323189 NBR1 0.72 12.12 0.55 2.21e-28 Menopause (age at onset); LIHC cis rs11148252 0.904 rs3892337 chr13:53029485 C/G cg00495681 chr13:53174319 NA 0.42 6.9 0.35 2.56e-11 Lewy body disease; LIHC cis rs6752107 0.782 rs12692254 chr2:234161211 A/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.36 0.41 1.55e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4925386 1.000 rs4925386 chr20:60921044 C/T cg06026331 chr20:60912101 LAMA5 0.5 8.54 0.42 4.44e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2806561 0.704 rs664301 chr1:23522522 C/T cg11953164 chr1:23521307 HTR1D 0.29 5.78 0.3 1.68e-8 Height; LIHC cis rs9814567 1.000 rs4417907 chr3:134291363 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.12 -0.55 2.19e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4927850 1.000 rs7627706 chr3:195753353 A/C cg01181863 chr3:195395398 SDHAP2 -0.5 -6.5 -0.33 2.81e-10 Pancreatic cancer; LIHC cis rs17401966 0.838 rs34565762 chr1:10300119 T/C cg19773385 chr1:10388646 KIF1B -0.39 -7.16 -0.36 4.84e-12 Hepatocellular carcinoma; LIHC cis rs11122272 0.766 rs2790871 chr1:231543555 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.87 -0.51 7.56e-24 Hemoglobin concentration; LIHC cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg06634786 chr22:41940651 POLR3H 0.74 7.67 0.38 1.78e-13 Vitiligo; LIHC cis rs763121 0.853 rs5750669 chr22:39080638 T/A cg06022373 chr22:39101656 GTPBP1 0.66 11.39 0.52 1.07e-25 Menopause (age at onset); LIHC trans rs35110281 0.807 rs4818850 chr21:45028071 T/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.28 0.32 1.05e-9 Mean corpuscular volume; LIHC cis rs1003719 0.715 rs2835667 chr21:38579914 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.23 -0.48 1.3e-21 Eye color traits; LIHC cis rs6089584 0.962 rs6142913 chr20:60566950 A/G cg13770153 chr20:60521292 NA -0.37 -7.42 -0.37 9.58e-13 Body mass index; LIHC trans rs17685 0.712 rs10235086 chr7:75833138 G/T cg19862616 chr7:65841803 NCRNA00174 0.91 18.3 0.7 1.27e-52 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg02290350 chr8:58132656 NA 0.49 10.55 0.5 1.07e-22 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg08219700 chr8:58056026 NA 0.52 6.22 0.32 1.43e-9 Developmental language disorder (linguistic errors); LIHC cis rs2276314 1.000 rs1540042 chr18:33555236 C/T cg05985134 chr18:33552581 C18orf21 0.49 5.86 0.3 1.11e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs2576037 0.562 rs612519 chr18:44379490 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.43 -5.99 -0.31 5.45e-9 Personality dimensions; LIHC cis rs9297145 0.585 rs17147666 chr7:98781457 A/C cg05967295 chr7:98741636 SMURF1 -0.4 -6.58 -0.34 1.74e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs6502050 0.799 rs12940433 chr17:80120826 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.62e-9 Life satisfaction; LIHC cis rs11588062 0.628 rs3737744 chr1:46810530 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 -0.44 -7.1 -0.36 7.12e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6598955 0.666 rs12759434 chr1:26607123 C/T cg04990556 chr1:26633338 UBXN11 -0.6 -9.81 -0.47 3.57e-20 Obesity-related traits; LIHC cis rs2153535 0.562 rs9379211 chr6:8463927 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg23205692 chr1:25664452 TMEM50A -0.39 -6.25 -0.32 1.24e-9 Erythrocyte sedimentation rate; LIHC cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9916302 0.904 rs11869109 chr17:37518205 G/T cg07936489 chr17:37558343 FBXL20 0.83 13.53 0.59 1.02e-33 Glomerular filtration rate (creatinine); LIHC cis rs12594515 1.000 rs6493175 chr15:45989898 T/C cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC cis rs853679 0.517 rs9368557 chr6:28131537 T/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC trans rs801193 0.839 rs6968619 chr7:66068867 T/C cg26939375 chr7:64535504 NA -0.43 -7.34 -0.37 1.62e-12 Aortic root size; LIHC cis rs2806561 0.808 rs2294518 chr1:23372771 T/C cg19743168 chr1:23544995 NA -0.36 -6.63 -0.34 1.3e-10 Height; LIHC cis rs2095921 1 rs2095921 chr1:11033322 C/G cg27631724 chr1:11040367 C1orf127 0.37 6.83 0.35 4.01e-11 Male-pattern baldness; LIHC cis rs2288073 0.965 rs10173173 chr2:24415461 G/T cg06627628 chr2:24431161 ITSN2 0.59 7.98 0.4 2.16e-14 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs1577917 0.655 rs9359658 chr6:86305769 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.16 0.44 4.81e-18 Response to antipsychotic treatment; LIHC trans rs8002861 0.781 rs9525857 chr13:44437072 T/C cg17145862 chr1:211918768 LPGAT1 0.58 10.69 0.5 3.2e-23 Leprosy; LIHC cis rs11711311 1.000 rs12631232 chr3:113497386 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.74 -0.34 6.83e-11 IgG glycosylation; LIHC cis rs7089973 0.564 rs55671354 chr10:116571281 T/C cg23260525 chr10:116636907 FAM160B1 0.37 7.01 0.35 1.24e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2637266 0.783 rs1797500 chr10:78510400 G/A cg18941641 chr10:78392320 NA 0.27 5.83 0.3 1.26e-8 Pulmonary function; LIHC cis rs1023500 0.551 rs133379 chr22:42468535 A/G cg05082376 chr22:42548792 NA -0.4 -5.92 -0.3 8e-9 Schizophrenia; LIHC cis rs652260 0.819 rs55656533 chr19:7902976 G/C cg26014689 chr19:7917955 EVI5L -0.66 -11.62 -0.53 1.6e-26 Menarche (age at onset); LIHC cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg07061783 chr6:25882402 NA -0.81 -11.29 -0.52 2.55e-25 Urate levels; LIHC cis rs765787 0.530 rs28524974 chr15:45543528 C/T cg25801113 chr15:45476975 SHF 0.38 6.58 0.34 1.78e-10 Uric acid levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03086376 chr16:1876114 HAGH;FAHD1 0.4 6.27 0.32 1.1e-9 Cognitive function; LIHC cis rs10508774 1.000 rs72795539 chr10:32842326 G/A cg01819863 chr10:32635814 EPC1 0.65 6.01 0.31 4.72e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1030877 0.960 rs3792047 chr2:105901553 A/G cg02079111 chr2:105885981 TGFBRAP1 -0.68 -12.12 -0.55 2.35e-28 Obesity-related traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11003645 chr6:143382007 AIG1 -0.55 -6.1 -0.31 2.9e-9 Systolic blood pressure; LIHC cis rs9768139 0.683 rs72505558 chr7:158113215 A/G cg25566285 chr7:158114605 PTPRN2 0.22 5.96 0.31 6.38e-9 Calcium levels; LIHC cis rs7607369 0.637 rs3731866 chr2:219288899 C/T cg02176678 chr2:219576539 TTLL4 -0.52 -6.99 -0.35 1.46e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs8180040 0.701 rs34103310 chr3:47073266 C/T cg02527881 chr3:46936655 PTH1R -0.32 -6.2 -0.32 1.62e-9 Colorectal cancer; LIHC cis rs56104184 0.775 rs56317021 chr19:49395960 C/T cg21252483 chr19:49399788 TULP2 -1.05 -11.96 -0.54 8.91e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg04944784 chr2:26401820 FAM59B -0.77 -9.44 -0.45 6.02e-19 Gut microbiome composition (summer); LIHC cis rs7953508 0.750 rs7310389 chr12:93976636 A/G cg18151635 chr12:93972918 NA -0.44 -6.9 -0.35 2.53e-11 Pubertal anthropometrics; LIHC cis rs17433710 0.543 rs7519400 chr1:162661603 G/T cg01063088 chr1:162760584 HSD17B7 0.44 6.22 0.32 1.43e-9 Dupuytren's disease; LIHC cis rs2576037 0.583 rs478820 chr18:44397782 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.89 -0.3 9.41e-9 Personality dimensions; LIHC cis rs921968 0.643 rs485765 chr2:219480804 C/G cg02985541 chr2:219472218 PLCD4 0.42 7.9 0.39 3.92e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs8067545 0.750 rs4267380 chr17:19971564 A/G cg13482628 chr17:19912719 NA 0.49 8.16 0.4 6.52e-15 Schizophrenia; LIHC cis rs34779708 0.966 rs34605125 chr10:35411246 A/G cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4450131 0.522 rs4962683 chr10:126371957 C/T cg20435097 chr10:126320824 FAM53B 0.67 12.22 0.55 9.74e-29 White blood cell count (basophil); LIHC cis rs9649213 0.537 rs6465663 chr7:97918883 C/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.96 -0.31 6.45e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs2749592 0.918 rs4934590 chr10:37877569 T/C cg17830980 chr10:43048298 ZNF37B 0.36 6.14 0.32 2.31e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs911555 0.673 rs7144271 chr14:103890674 A/G cg17675199 chr6:35436792 RPL10A 0.39 7.86 0.39 4.92e-14 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg04267008 chr7:1944627 MAD1L1 -0.6 -9.48 -0.46 4.55e-19 Bipolar disorder and schizophrenia; LIHC cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.84 8.59 0.42 3.05e-16 Platelet count; LIHC trans rs801193 1.000 rs2707836 chr7:66160435 A/C cg26939375 chr7:64535504 NA 0.43 6.84 0.35 3.67e-11 Aortic root size; LIHC cis rs709400 0.659 rs7160366 chr14:103944137 C/T cg26031613 chr14:104095156 KLC1 0.73 9.24 0.45 2.62e-18 Body mass index; LIHC cis rs12478296 0.681 rs73007114 chr2:242984903 T/C cg05760424 chr2:242988095 NA -0.55 -7.32 -0.37 1.79e-12 Obesity-related traits; LIHC cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg06634786 chr22:41940651 POLR3H -0.7 -7.76 -0.39 9.65e-14 Vitiligo; LIHC cis rs2645694 0.532 rs2645706 chr4:77829606 A/C cg03477792 chr4:77819574 ANKRD56 0.56 7.47 0.37 6.62e-13 Emphysema distribution in smoking; LIHC cis rs2228479 0.850 rs11645916 chr16:89835234 G/A cg19635926 chr16:89946313 TCF25 0.48 6.17 0.32 1.97e-9 Skin colour saturation; LIHC cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg05896524 chr21:47604654 C21orf56 0.45 6.78 0.34 5.34e-11 Testicular germ cell tumor; LIHC cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4474465 0.790 rs4945290 chr11:78252249 C/T cg27205649 chr11:78285834 NARS2 0.39 6.15 0.32 2.14e-9 Alzheimer's disease (survival time); LIHC cis rs7945705 0.875 rs2653616 chr11:8885892 A/G cg12365402 chr11:9010492 NRIP3 -0.25 -6.3 -0.32 9.39e-10 Hemoglobin concentration; LIHC cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg19318889 chr4:1322082 MAEA 0.47 6.59 0.34 1.71e-10 Obesity-related traits; LIHC cis rs4319547 0.915 rs10734924 chr12:123018894 T/G cg23029597 chr12:123009494 RSRC2 -0.53 -7.47 -0.37 6.76e-13 Body mass index; LIHC cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg21782813 chr7:2030301 MAD1L1 0.44 7.54 0.38 4.16e-13 Bipolar disorder and schizophrenia; LIHC cis rs2439831 0.850 rs11070408 chr15:44034788 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.39 0.41 1.33e-15 Lung cancer in ever smokers; LIHC cis rs10791097 0.667 rs4937584 chr11:130741761 A/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.46 7.69 0.38 1.62e-13 Height; LIHC trans rs66573146 0.572 rs67750430 chr4:6957266 T/G cg07817883 chr1:32538562 TMEM39B 1.02 9.16 0.44 4.93e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs34779708 0.931 rs2505631 chr10:35368385 A/T cg03585969 chr10:35415529 CREM -0.77 -11.65 -0.53 1.23e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs992157 0.764 rs1870123 chr2:219187698 G/A cg00012203 chr2:219082015 ARPC2 0.76 10.61 0.5 6.43e-23 Colorectal cancer; LIHC cis rs7312933 0.618 rs6582390 chr12:42634586 C/T cg17420585 chr12:42539391 GXYLT1 -0.37 -5.95 -0.31 6.49e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2842992 0.724 rs15982 chr6:160199687 T/C cg11366901 chr6:160182831 ACAT2 0.86 14.98 0.63 2.4e-39 Age-related macular degeneration (geographic atrophy); LIHC cis rs2302190 0.882 rs11658998 chr17:56655786 T/G cg12560992 chr17:57184187 TRIM37 0.69 8.91 0.43 3.17e-17 Vitamin D levels; LIHC cis rs6061231 1.000 rs11696991 chr20:60959694 G/T cg22601191 chr20:60968625 CABLES2 0.4 5.75 0.3 1.98e-8 Colorectal cancer; LIHC cis rs57590327 0.503 rs2372906 chr3:81504673 G/A cg07356753 chr3:81810745 GBE1 0.46 6.8 0.35 4.6e-11 Extraversion; LIHC cis rs9612 1.000 rs346523 chr19:44260681 A/C cg08581076 chr19:44259116 C19orf61 0.7 8.95 0.44 2.37e-17 Exhaled nitric oxide output; LIHC cis rs7116495 1.000 rs671681 chr11:71782812 T/C cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs9872999 1 rs9872999 chr3:133457514 C/T cg24879335 chr3:133465180 TF 0.47 10.94 0.51 4.29e-24 Iron status biomarkers; LIHC cis rs7843479 1.000 rs2306641 chr8:21833965 A/G cg17168535 chr8:21777572 XPO7 -0.44 -7.16 -0.36 4.93e-12 Mean corpuscular volume; LIHC cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.44e-29 Menopause (age at onset); LIHC cis rs2033711 0.728 rs4801586 chr19:58934528 A/G cg13877915 chr19:58951672 ZNF132 0.57 8.86 0.43 4.43e-17 Uric acid clearance; LIHC cis rs5769707 0.777 rs739243 chr22:50057211 C/T cg07959070 chr22:50026188 C22orf34 -0.28 -6.98 -0.35 1.55e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.76 0.39 9.67e-14 Schizophrenia; LIHC cis rs7914558 1.000 rs4917996 chr10:104925829 A/C cg15744005 chr10:104629667 AS3MT -0.39 -8.88 -0.43 3.84e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10751667 0.621 rs11246375 chr11:999620 T/C ch.11.42038R chr11:967971 AP2A2 0.6 11.25 0.52 3.48e-25 Alzheimer's disease (late onset); LIHC cis rs2204008 0.775 rs3900361 chr12:38238936 A/G cg13010199 chr12:38710504 ALG10B -0.49 -5.96 -0.31 6.27e-9 Bladder cancer; LIHC cis rs9733 0.818 rs7520022 chr1:150659173 C/G cg18016565 chr1:150552671 MCL1 -0.5 -10.44 -0.49 2.43e-22 Tonsillectomy; LIHC cis rs26868 0.742 rs26848 chr16:2263516 A/G cg02248941 chr16:2239361 CASKIN1 0.29 6.26 0.32 1.13e-9 Height; LIHC trans rs1427593 1.000 rs1896473 chr2:137533702 C/T cg04243827 chr5:3103718 NA 0.41 6.11 0.31 2.74e-9 Pancreatic cancer; LIHC cis rs1707322 0.717 rs2253862 chr1:46081960 C/T cg24296786 chr1:45957014 TESK2 0.4 5.71 0.3 2.44e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2204008 0.506 rs11495470 chr12:38026904 C/T cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC cis rs4713118 0.516 rs7739216 chr6:28079946 G/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Parkinson's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02982722 chr20:44486048 ZSWIM3;ACOT8 0.49 6.52 0.33 2.57e-10 Lung function (FEV1/FVC); LIHC cis rs9811920 0.609 rs793466 chr3:99609837 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs1451375 0.617 rs745043 chr7:50543955 T/G cg14593290 chr7:50529359 DDC -0.62 -9.71 -0.46 7.53e-20 Malaria; LIHC cis rs11958404 1.000 rs72816528 chr5:157410949 G/A cg05962755 chr5:157440814 NA 0.88 10.05 0.48 5.43e-21 IgG glycosylation; LIHC cis rs921968 0.541 rs561570 chr2:219379348 T/A cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7618915 0.547 rs11719685 chr3:52676065 C/T cg18404041 chr3:52824283 ITIH1 -0.58 -9.08 -0.44 8.98e-18 Bipolar disorder; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg07489123 chr19:1812466 ATP8B3 -0.42 -6.15 -0.32 2.17e-9 Neuroblastoma; LIHC cis rs5769765 0.505 rs4561759 chr22:50256686 C/T cg09182678 chr22:50328711 NA 0.47 6.0 0.31 5.14e-9 Schizophrenia; LIHC cis rs11758351 0.866 rs55815656 chr6:26207303 G/A cg11342453 chr6:26196699 NA 0.52 5.8 0.3 1.55e-8 Gout;Renal underexcretion gout; LIHC cis rs9811920 0.609 rs793447 chr3:99598278 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs9902453 0.780 rs62068621 chr17:28170382 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.33 0.55 3.77e-29 Coffee consumption (cups per day); LIHC cis rs7129220 0.588 rs7946649 chr11:10107980 G/C cg01453529 chr11:10209919 SBF2 -0.4 -7.0 -0.35 1.33e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs986417 0.892 rs57925468 chr14:60816129 G/A cg27398547 chr14:60952738 C14orf39 -0.77 -8.71 -0.43 1.28e-16 Gut microbiota (bacterial taxa); LIHC cis rs546131 0.642 rs7946980 chr11:34820438 C/T cg11058730 chr11:34937778 PDHX;APIP 0.58 8.69 0.43 1.52e-16 Lung disease severity in cystic fibrosis; LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg06420487 chr17:61919686 SMARCD2 0.43 5.85 0.3 1.14e-8 Height; LIHC cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg06481639 chr22:41940642 POLR3H 0.71 7.06 0.36 9.26e-12 Vitiligo; LIHC cis rs9921222 0.585 rs7195617 chr16:376781 A/G cg12437481 chr16:420112 MRPL28 0.51 7.9 0.39 3.82e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs908922 0.885 rs2181173 chr1:152474866 A/T cg20991723 chr1:152506922 NA -0.49 -8.85 -0.43 4.69e-17 Hair morphology; LIHC cis rs2180341 0.960 rs7766942 chr6:127691323 G/T cg27446573 chr6:127587934 RNF146 1.0 15.51 0.64 1.82e-41 Breast cancer; LIHC cis rs694739 0.595 rs11606015 chr11:64136877 C/G cg23796481 chr11:64053134 BAD;GPR137 0.46 6.22 0.32 1.42e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs2795502 0.766 rs947549 chr10:43265880 G/C cg20628663 chr10:43360327 NA -0.47 -7.21 -0.36 3.65e-12 Blood protein levels; LIHC cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg13047869 chr3:10149882 C3orf24 0.54 6.41 0.33 4.82e-10 Alzheimer's disease; LIHC cis rs4563143 0.663 rs10417671 chr19:29235335 T/C cg04546413 chr19:29218101 NA 0.38 7.38 0.37 1.23e-12 Methadone dose in opioid dependence; LIHC trans rs983392 0.709 rs7932740 chr11:59976111 G/A cg17275991 chr19:58003312 ZNF419 0.44 6.17 0.32 1.92e-9 Alzheimer's disease (late onset); LIHC cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg08280861 chr8:58055591 NA 0.54 6.28 0.32 1.05e-9 Developmental language disorder (linguistic errors); LIHC cis rs6893300 0.524 rs6601073 chr5:179177271 A/G cg14593053 chr5:179126677 CANX -0.45 -8.1 -0.4 1e-14 Resting heart rate; LIHC cis rs4759375 1.000 rs9669295 chr12:123842670 A/G cg00376283 chr12:123451042 ABCB9 0.49 6.31 0.32 8.57e-10 HDL cholesterol; LIHC cis rs9611565 0.559 rs5758397 chr22:42019251 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.67 0.5 4.01e-23 Vitiligo; LIHC trans rs2797160 1.000 rs1832980 chr6:125997444 T/G cg05039488 chr6:79577232 IRAK1BP1 -0.44 -6.4 -0.33 5.23e-10 Endometrial cancer; LIHC cis rs13256369 1.000 rs9329166 chr8:8576655 C/T cg17143192 chr8:8559678 CLDN23 0.69 11.32 0.52 1.84e-25 Obesity-related traits; LIHC cis rs67478160 0.643 rs8004408 chr14:104203938 G/A cg08213375 chr14:104286397 PPP1R13B 0.65 12.91 0.57 2.39e-31 Schizophrenia; LIHC cis rs9916302 0.904 rs7216086 chr17:37709422 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.23 -0.58 1.45e-32 Glomerular filtration rate (creatinine); LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg11494091 chr17:61959527 GH2 0.35 5.86 0.3 1.11e-8 Height; LIHC trans rs2727020 0.757 rs7924526 chr11:49267043 G/A cg18944383 chr4:111397179 ENPEP -0.28 -6.52 -0.33 2.55e-10 Coronary artery disease; LIHC trans rs208520 1.000 rs28773210 chr6:66993566 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 7.14 0.36 5.52e-12 Exhaled nitric oxide output; LIHC cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg06238570 chr21:40685208 BRWD1 0.62 7.69 0.38 1.55e-13 Cognitive function; LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.56 8.17 0.4 5.85e-15 Lymphocyte counts; LIHC cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg18357526 chr6:26021779 HIST1H4A 0.58 8.04 0.4 1.49e-14 Blood metabolite levels; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg11494091 chr17:61959527 GH2 0.45 8.41 0.41 1.09e-15 Prudent dietary pattern; LIHC cis rs2066819 1.000 rs79101914 chr12:56729739 A/G cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs2559856 0.903 rs10128996 chr12:102081498 G/A cg12924262 chr12:102091054 CHPT1 0.5 7.95 0.4 2.7e-14 Blood protein levels; LIHC cis rs1801251 0.964 rs13007783 chr2:233566679 G/A cg08000102 chr2:233561755 GIGYF2 0.75 11.25 0.52 3.35e-25 Coronary artery disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07798295 chr16:89715839 CHMP1A 0.45 6.37 0.33 6.12e-10 Longevity; LIHC cis rs4409675 0.576 rs2815707 chr1:28238880 T/C cg23691781 chr1:28212827 C1orf38 0.32 7.47 0.37 6.86e-13 Corneal astigmatism; LIHC cis rs1059312 0.966 rs12368452 chr12:129277164 C/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -13.99 -0.6 1.8e-35 Systemic lupus erythematosus; LIHC cis rs7312933 0.865 rs1920687 chr12:42398275 T/C cg01256987 chr12:42539512 GXYLT1 -0.37 -6.27 -0.32 1.12e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg11494091 chr17:61959527 GH2 0.44 8.15 0.4 7.02e-15 Prudent dietary pattern; LIHC cis rs1348850 0.574 rs2365617 chr2:178421934 C/A cg27490568 chr2:178487706 NA 1.06 11.8 0.54 3.33e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.73 -0.3 2.23e-8 Total body bone mineral density; LIHC cis rs4407350 0.870 rs135627 chr22:44906402 A/G cg26276947 chr22:44892394 LDOC1L 0.36 6.81 0.35 4.28e-11 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg02290350 chr8:58132656 NA 0.4 8.44 0.42 9.38e-16 Developmental language disorder (linguistic errors); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg04814990 chr13:111957387 ARHGEF7 0.39 6.23 0.32 1.37e-9 Immature fraction of reticulocytes; LIHC cis rs11588062 0.628 rs11211270 chr1:46838986 C/T cg15696662 chr1:46669221 C1orf190;POMGNT1 0.41 6.32 0.32 8.05e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6964587 0.869 rs11769294 chr7:91549937 C/T cg17063962 chr7:91808500 NA 0.93 17.55 0.69 1.33e-49 Breast cancer; LIHC cis rs34330 0.562 rs17212236 chr12:12855483 G/C cg04607235 chr12:12878440 APOLD1 -0.76 -9.22 -0.45 3.09e-18 Systemic lupus erythematosus; LIHC cis rs8180040 0.764 rs6794193 chr3:47114904 T/C cg02527881 chr3:46936655 PTH1R -0.31 -6.14 -0.32 2.23e-9 Colorectal cancer; LIHC cis rs9733 0.596 rs72702580 chr1:150691285 A/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs9818758 0.607 rs9855123 chr3:49229457 C/T cg00383909 chr3:49044727 WDR6 0.8 6.67 0.34 1.05e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2304069 0.507 rs4705407 chr5:149404983 G/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.52 7.33 0.37 1.69e-12 HIV-1 control; LIHC cis rs986417 1.000 rs1254324 chr14:60908551 C/T cg27398547 chr14:60952738 C14orf39 -0.82 -9.65 -0.46 1.24e-19 Gut microbiota (bacterial taxa); LIHC cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.8 6.29 0.32 9.85e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6450176 0.830 rs7718193 chr5:53291591 T/G ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.29 -0.64 1.35e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg09299307 chr5:86709023 CCNH 0.37 6.06 0.31 3.58e-9 Metabolic traits; LIHC cis rs4803468 0.967 rs3786553 chr19:41902746 T/G cg14132834 chr19:41945861 ATP5SL -0.43 -6.45 -0.33 3.82e-10 Height; LIHC cis rs244293 0.965 rs2787482 chr17:53210774 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs7000551 0.688 rs2948145 chr8:22367792 T/C cg12081754 chr8:22256438 SLC39A14 0.44 7.32 0.37 1.81e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs11676348 0.901 rs7562334 chr2:219003360 G/A cg00012203 chr2:219082015 ARPC2 -0.53 -7.25 -0.37 2.79e-12 Ulcerative colitis; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg09033563 chr22:24373618 LOC391322 -0.43 -5.92 -0.31 7.63e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4700695 0.668 rs153393 chr5:65428707 A/G cg21114390 chr5:65439923 SFRS12 -0.58 -8.45 -0.42 8.51e-16 Facial morphology (factor 19); LIHC cis rs6964587 0.626 rs12704631 chr7:91523525 T/C cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.22e-24 Breast cancer; LIHC cis rs2292096 1.000 rs66530019 chr1:200813692 A/T cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -6.07 -0.31 3.33e-9 Epilepsy; LIHC cis rs16828019 0.852 rs71648540 chr1:41722295 G/A cg20697417 chr1:41786797 NA 0.34 6.55 0.33 2.11e-10 Intelligence (multi-trait analysis); LIHC cis rs332507 0.560 rs6806224 chr3:124365803 C/T cg05980111 chr3:124395277 KALRN 0.31 5.85 0.3 1.17e-8 Plateletcrit; LIHC cis rs12701220 0.553 rs7782024 chr7:1157502 G/T cg09177884 chr7:1199841 ZFAND2A -0.51 -5.83 -0.3 1.28e-8 Bronchopulmonary dysplasia; LIHC cis rs1163251 0.837 rs595283 chr1:120247887 C/G cg19096424 chr1:120255104 PHGDH -0.64 -8.18 -0.4 5.45e-15 Blood metabolite levels; LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg12379764 chr21:47803548 PCNT -0.57 -8.34 -0.41 1.88e-15 Testicular germ cell tumor; LIHC cis rs6547741 0.844 rs7586655 chr2:27915659 A/G cg27432699 chr2:27873401 GPN1 -0.93 -16.58 -0.67 9.83e-46 Oral cavity cancer; LIHC cis rs1395 0.922 rs13404327 chr2:27519153 G/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.01 -0.31 4.81e-9 Blood metabolite levels; LIHC cis rs986417 1.000 rs2144114 chr14:61064210 T/C cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC trans rs1728785 1.000 rs1728789 chr16:68595776 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.5 0.33 2.82e-10 Ulcerative colitis; LIHC cis rs1005277 0.579 rs1740735 chr10:38497777 A/C cg17219203 chr10:38645113 HSD17B7P2 -0.4 -5.77 -0.3 1.75e-8 Extrinsic epigenetic age acceleration; LIHC cis rs1003719 0.762 rs4399800 chr21:38489478 G/T cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.94 0.54 1.01e-27 Eye color traits; LIHC cis rs7772486 0.686 rs857880 chr6:145971115 T/C cg23711669 chr6:146136114 FBXO30 -0.7 -12.65 -0.56 2.45e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs7089973 0.604 rs2420069 chr10:116605103 A/G cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4629710 0.592 rs11759926 chr6:131571269 G/T cg12606694 chr6:131520996 AKAP7 0.66 7.62 0.38 2.5e-13 Multiple myeloma (IgH translocation); LIHC cis rs1568889 1.000 rs12794100 chr11:28332785 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.9 0.35 2.48e-11 Bipolar disorder; LIHC cis rs12497850 0.864 rs7431857 chr3:48900347 G/A cg06212747 chr3:49208901 KLHDC8B 0.56 7.21 0.36 3.56e-12 Parkinson's disease; LIHC cis rs2439831 0.702 rs3759791 chr15:44090798 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.59 8.37 0.41 1.54e-15 Lung cancer in ever smokers; LIHC cis rs17685 0.753 rs6953665 chr7:75769049 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12477438 0.765 rs2278895 chr2:99613484 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.26 -0.41 3.31e-15 Chronic sinus infection; LIHC cis rs748404 0.578 rs507178 chr15:43610135 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.58 9.22 0.45 3.23e-18 Lung cancer; LIHC cis rs1005277 0.541 rs2472177 chr10:38384015 T/G cg00409905 chr10:38381863 ZNF37A -0.59 -10.31 -0.49 6.75e-22 Extrinsic epigenetic age acceleration; LIHC trans rs975809 0.966 rs11004607 chr10:56622686 G/T cg01052087 chr20:10414899 C20orf94;MKKS 0.44 6.23 0.32 1.4e-9 Carotid intima media thickness; LIHC cis rs10791097 1.000 rs10791097 chr11:130718630 G/T cg12179176 chr11:130786555 SNX19 -0.61 -9.42 -0.45 6.97e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs1945213 0.694 rs7116741 chr11:55862620 C/T cg15704280 chr7:45808275 SEPT13 0.59 7.68 0.38 1.71e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs1577917 0.655 rs9359658 chr6:86305769 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.34 6.23 0.32 1.34e-9 Response to antipsychotic treatment; LIHC cis rs12450688 1 rs12450688 chr17:38144229 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.67 11.78 0.54 4.19e-27 Sum eosinophil basophil counts; LIHC cis rs202629 1 rs202629 chr22:41849975 C/T cg06634786 chr22:41940651 POLR3H 0.8 8.97 0.44 1.94e-17 Cannabis dependence symptom count; LIHC cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs600806 0.850 rs1880670 chr1:109941133 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs2832191 0.720 rs4643617 chr21:30485278 T/C cg08807101 chr21:30365312 RNF160 -0.63 -10.01 -0.48 7.58e-21 Dental caries; LIHC cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg10802521 chr3:52805072 NEK4 -0.4 -6.64 -0.34 1.27e-10 Electroencephalogram traits; LIHC cis rs6674176 0.597 rs6671164 chr1:44403489 G/T cg12908607 chr1:44402522 ARTN -0.51 -8.68 -0.43 1.59e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7772486 0.790 rs4280983 chr6:146280790 G/C cg13319975 chr6:146136371 FBXO30 0.4 6.32 0.32 8.03e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.642 rs11817852 chr10:99158426 C/T cg06359132 chr10:99160096 RRP12 -0.42 -6.37 -0.33 5.93e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7927592 0.913 rs66752716 chr11:68273626 C/T cg16797656 chr11:68205561 LRP5 0.52 8.25 0.41 3.4e-15 Total body bone mineral density; LIHC cis rs507080 0.733 rs489126 chr11:118572747 G/A cg04173919 chr11:118528438 PHLDB1 0.33 6.09 0.31 2.98e-9 Serum metabolite levels; LIHC cis rs2288073 0.965 rs13395596 chr2:24410738 T/C cg06627628 chr2:24431161 ITSN2 -0.58 -7.63 -0.38 2.32e-13 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.931 rs12268745 chr10:35305989 C/G cg03585969 chr10:35415529 CREM 0.84 12.88 0.57 3.26e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs507080 0.733 rs611733 chr11:118572760 C/T cg04173919 chr11:118528438 PHLDB1 0.32 6.01 0.31 4.86e-9 Serum metabolite levels; LIHC cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg10802521 chr3:52805072 NEK4 -0.43 -6.89 -0.35 2.67e-11 Bipolar disorder; LIHC cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.863 rs3733525 chr4:120447048 A/G cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs6840360 0.571 rs11944139 chr4:152505291 T/C cg22705602 chr4:152727874 NA -0.31 -6.04 -0.31 4.08e-9 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.934 rs7316004 chr12:29411698 C/T cg00204748 chr12:29376779 FAR2 0.44 8.32 0.41 2.08e-15 QT interval; LIHC cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg11764359 chr7:65958608 NA 0.69 9.4 0.45 8.19e-19 Calcium levels; LIHC cis rs4665809 0.549 rs17527979 chr2:26428132 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.11 -13.55 -0.59 9.17e-34 Gut microbiome composition (summer); LIHC cis rs7666738 0.546 rs10018080 chr4:98758436 C/A cg05340658 chr4:99064831 C4orf37 0.49 6.3 0.32 9.41e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs2153535 0.580 rs1414350 chr6:8472331 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs10089 1.000 rs4836360 chr5:127458161 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.8 0.34 4.77e-11 Ileal carcinoids; LIHC cis rs2932538 0.744 rs6537742 chr1:113085197 G/T cg22162597 chr1:113214053 CAPZA1 0.6 7.74 0.39 1.13e-13 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs9611565 0.694 rs5758324 chr22:41787950 G/T cg03806693 chr22:41940476 POLR3H -0.58 -7.81 -0.39 7.15e-14 Vitiligo; LIHC cis rs7635838 0.892 rs9310383 chr3:11491305 A/G cg00170343 chr3:11313890 ATG7 -0.37 -5.78 -0.3 1.72e-8 HDL cholesterol; LIHC cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg23978390 chr7:1156363 C7orf50 0.6 9.2 0.45 3.49e-18 Longevity;Endometriosis; LIHC cis rs10916814 0.546 rs7547998 chr1:20903192 C/T cg24502330 chr1:20914028 CDA -0.3 -6.6 -0.34 1.55e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10256972 0.869 rs1007766 chr7:1034903 G/A cg16145915 chr7:1198662 ZFAND2A -0.29 -6.84 -0.35 3.58e-11 Longevity;Endometriosis; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg26338869 chr17:61819248 STRADA 0.58 8.61 0.42 2.7e-16 Prudent dietary pattern; LIHC cis rs9911578 0.935 rs117819974 chr17:57002324 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs1538970 0.504 rs3790585 chr1:46023356 A/T cg24296786 chr1:45957014 TESK2 -0.48 -5.92 -0.3 8.04e-9 Platelet count; LIHC cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg10755058 chr3:40428713 ENTPD3 0.35 6.04 0.31 4.08e-9 Renal cell carcinoma; LIHC cis rs250677 0.687 rs3095947 chr5:148436728 T/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.52 -0.38 4.9e-13 Breast cancer; LIHC cis rs3823572 0.504 rs2346268 chr7:133642742 G/A cg03336402 chr7:133662267 EXOC4 -0.46 -5.71 -0.3 2.4e-8 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15757022 chr11:71163853 NADSYN1 -0.46 -6.38 -0.33 5.7e-10 Pancreatic cancer; LIHC cis rs939574 0.790 rs72955447 chr2:220098287 G/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.88 6.38 0.33 5.72e-10 Platelet distribution width; LIHC cis rs700651 0.675 rs1371665 chr2:198942568 C/T cg10820045 chr2:198174542 NA 0.4 6.02 0.31 4.38e-9 Intracranial aneurysm; LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC cis rs910316 0.789 rs175444 chr14:75601782 G/C cg11812906 chr14:75593930 NEK9 -0.73 -13.82 -0.6 7.89e-35 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21548788 chr4:77997565 CCNI 0.44 6.09 0.31 3.05e-9 Pancreatic cancer; LIHC cis rs7772486 0.754 rs4566902 chr6:146244128 A/G cg05347473 chr6:146136440 FBXO30 -0.37 -5.91 -0.3 8.14e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7666738 0.519 rs11732209 chr4:98801643 A/G cg05340658 chr4:99064831 C4orf37 0.49 6.36 0.33 6.5e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7587476 0.643 rs6714373 chr2:215719014 A/G cg04530015 chr2:215796436 ABCA12 -0.36 -5.78 -0.3 1.71e-8 Neuroblastoma; LIHC cis rs1816752 0.819 rs7316961 chr13:24985177 C/T cg22771759 chr13:24902376 NA 0.29 5.73 0.3 2.19e-8 Obesity-related traits; LIHC cis rs6459804 1.000 rs6459805 chr7:157510294 T/C cg05731713 chr7:157510257 PTPRN2 0.23 6.36 0.33 6.38e-10 Bipolar disorder and schizophrenia; LIHC cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg06453172 chr10:134556979 INPP5A -0.63 -7.87 -0.39 4.87e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7187994 0.848 rs12448489 chr16:84774022 G/A cg07647771 chr16:84786436 USP10 -0.33 -5.8 -0.3 1.52e-8 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.56 0.5 9.32e-23 Platelet count; LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.89 -0.3 9.14e-9 Total body bone mineral density; LIHC cis rs2153535 0.580 rs7453115 chr6:8447261 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.04e-16 Motion sickness; LIHC cis rs155076 1.000 rs261407 chr13:21855213 C/A cg11317459 chr13:21872234 NA -1.16 -13.64 -0.59 4.12e-34 White matter hyperintensity burden; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02047359 chr10:75174015 ANXA7 0.5 7.43 0.37 8.95e-13 Pancreatic cancer; LIHC cis rs7474896 0.583 rs11011341 chr10:37998500 G/A cg25427524 chr10:38739819 LOC399744 -0.49 -7.24 -0.36 3.04e-12 Obesity (extreme); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg16015499 chr1:159888603 TAGLN2 0.41 6.46 0.33 3.57e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10791323 0.628 rs4937838 chr11:133733406 T/C cg06766960 chr11:133703094 NA -0.59 -9.36 -0.45 1.09e-18 Childhood ear infection; LIHC cis rs599083 0.530 rs491347 chr11:68169688 G/A cg16797656 chr11:68205561 LRP5 -0.48 -7.47 -0.37 6.85e-13 Bone mineral density (spine); LIHC cis rs6728642 0.572 rs60621865 chr2:97598001 T/C cg26665480 chr2:98280029 ACTR1B -0.51 -6.39 -0.33 5.38e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg17971929 chr21:40555470 PSMG1 0.81 9.63 0.46 1.41e-19 Cognitive function; LIHC cis rs477692 0.837 rs543454 chr10:131420536 T/C cg05714579 chr10:131428358 MGMT 0.48 8.19 0.4 5.43e-15 Response to temozolomide; LIHC cis rs6684514 0.885 rs12036837 chr1:156283895 A/C cg16558208 chr1:156270281 VHLL 0.55 10.14 0.48 2.72e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs244293 0.899 rs2787489 chr17:53208136 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg09222892 chr1:25734099 RHCE 0.48 8.83 0.43 5.5e-17 Erythrocyte sedimentation rate; LIHC cis rs10503871 0.625 rs13275869 chr8:30310335 T/C cg26383811 chr8:30366931 RBPMS 0.4 6.9 0.35 2.61e-11 Metabolite levels (X-11787); LIHC cis rs738322 0.935 rs2413503 chr22:38568944 A/T cg25457927 chr22:38595422 NA -0.25 -6.23 -0.32 1.38e-9 Cutaneous nevi; LIHC cis rs3845702 0.736 rs3843323 chr2:180856459 T/C cg01881094 chr2:180872142 CWC22 -1.15 -10.34 -0.49 5.63e-22 Schizophrenia; LIHC cis rs367615 0.552 rs2963025 chr5:108733256 A/C cg17395555 chr5:108820864 NA -0.28 -5.94 -0.31 7.1e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs8017423 0.935 rs4643251 chr14:90669256 C/T cg04374321 chr14:90722782 PSMC1 -0.74 -13.97 -0.6 2.06e-35 Mortality in heart failure; LIHC cis rs7572733 0.555 rs6745726 chr2:198934080 A/G cg10820045 chr2:198174542 NA 0.41 6.03 0.31 4.23e-9 Dermatomyositis; LIHC trans rs62103177 0.568 rs2365388 chr18:77973702 G/T cg05926928 chr17:57297772 GDPD1 0.61 6.14 0.32 2.35e-9 Opioid sensitivity; LIHC cis rs7577696 0.568 rs7574000 chr2:32342888 A/C cg02381751 chr2:32503542 YIPF4 -0.45 -6.35 -0.32 6.89e-10 Inflammatory biomarkers; LIHC cis rs8062405 0.691 rs743590 chr16:28608230 G/A cg00204512 chr16:28754710 NA 0.43 7.48 0.37 6.44e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs950169 0.845 rs4106951 chr15:84833394 C/G cg03959625 chr15:84868606 LOC388152 0.44 6.47 0.33 3.31e-10 Schizophrenia; LIHC cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.85e-26 Platelet count; LIHC cis rs1008375 0.966 rs4698619 chr4:17580955 G/A cg02297831 chr4:17616191 MED28 0.48 7.23 0.36 3.19e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22024783 chr19:45393916 TOMM40 0.47 6.53 0.33 2.41e-10 Lung function (FEV1/FVC); LIHC cis rs10752881 1.000 rs6701400 chr1:182977197 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs2228479 0.702 rs12600047 chr16:89831630 G/A cg00800038 chr16:89945340 TCF25 -0.59 -8.71 -0.43 1.33e-16 Skin colour saturation; LIHC cis rs921968 0.643 rs2556384 chr2:219532903 C/T cg02985541 chr2:219472218 PLCD4 -0.44 -7.99 -0.4 2.04e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs4332037 0.722 rs7788921 chr7:1915282 C/A cg23043544 chr7:2124092 MAD1L1 -0.42 -6.23 -0.32 1.39e-9 Bipolar disorder; LIHC cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg12310025 chr6:25882481 NA -0.6 -8.59 -0.42 3.21e-16 Blood metabolite levels; LIHC cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg10802521 chr3:52805072 NEK4 -0.42 -6.87 -0.35 3.02e-11 Bipolar disorder; LIHC cis rs9517320 0.515 rs4772101 chr13:99207554 G/A cg07423050 chr13:99094983 FARP1 -0.5 -8.76 -0.43 9.45e-17 Longevity; LIHC cis rs694739 1.000 rs694739 chr11:64097233 A/G cg02228329 chr11:64053129 BAD;GPR137 0.75 10.72 0.5 2.67e-23 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs2404602 0.692 rs60658665 chr15:77042508 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.7e-9 Blood metabolite levels; LIHC cis rs12497850 0.966 rs6792510 chr3:48723302 G/C cg07636037 chr3:49044803 WDR6 0.8 13.19 0.58 2.11e-32 Parkinson's disease; LIHC cis rs6674176 0.660 rs12726706 chr1:44399942 G/A cg12908607 chr1:44402522 ARTN -0.47 -7.86 -0.39 5.09e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8078723 0.714 rs3785550 chr17:38149727 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.35 0.52 1.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs10861342 1.000 rs11112394 chr12:105551570 C/T cg23923672 chr12:105501055 KIAA1033 -0.66 -7.93 -0.39 3.22e-14 IgG glycosylation; LIHC cis rs7727544 0.735 rs274559 chr5:131720070 A/G cg24060327 chr5:131705240 SLC22A5 0.6 8.63 0.42 2.42e-16 Blood metabolite levels; LIHC cis rs11122272 0.735 rs2790897 chr1:231491712 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.87 -0.51 7.85e-24 Hemoglobin concentration; LIHC cis rs79149102 0.579 rs58645417 chr15:75325858 T/G cg16226627 chr15:75307476 SCAMP5 0.52 9.27 0.45 2.09e-18 Lung cancer; LIHC cis rs1580019 0.587 rs2392069 chr7:32547154 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.12 0.31 2.56e-9 Cognitive ability; LIHC cis rs4819052 1.000 rs2297285 chr21:46705621 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.67 -8.42 -0.41 1.02e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.89 0.39 4.06e-14 Height; LIHC trans rs9929218 0.551 rs3785135 chr16:68728976 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.91 -21.15 -0.75 4.27e-64 Colorectal cancer; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg05064044 chr6:292385 DUSP22 -0.53 -6.92 -0.35 2.22e-11 Menopause (age at onset); LIHC trans rs2504916 0.830 rs2504934 chr6:160781666 A/G cg27124293 chr6:170124346 PHF10 -0.56 -6.61 -0.34 1.49e-10 Response to hepatitis C treatment; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18305365 chr7:36007211 NA 0.39 6.08 0.31 3.17e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09379601 chr19:12992224 DNASE2 0.42 6.9 0.35 2.59e-11 Cognitive function; LIHC cis rs7737355 0.947 rs7724769 chr5:130954943 C/T cg06307176 chr5:131281290 NA 0.41 5.81 0.3 1.42e-8 Life satisfaction; LIHC cis rs2439831 0.850 rs558656 chr15:43723514 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.78 13.44 0.59 2.41e-33 Lung cancer in ever smokers; LIHC cis rs7408868 1.000 rs7254735 chr19:15263385 A/G cg02272795 chr19:15279244 NOTCH3 -0.34 -6.41 -0.33 4.84e-10 Pulse pressure; LIHC cis rs9297145 0.724 rs6954584 chr7:98766930 G/A cg05967295 chr7:98741636 SMURF1 0.72 10.31 0.49 7.11e-22 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC trans rs916888 0.821 rs199509 chr17:44858728 G/A cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2404602 0.692 rs8043474 chr15:76974723 T/C cg23625390 chr15:77176239 SCAPER 0.35 5.78 0.3 1.64e-8 Blood metabolite levels; LIHC cis rs36051895 0.623 rs12349113 chr9:5254224 T/A cg02405213 chr9:5042618 JAK2 -0.58 -9.58 -0.46 2.11e-19 Pediatric autoimmune diseases; LIHC cis rs11098499 1.000 rs11098500 chr4:120219239 T/A cg09307838 chr4:120376055 NA 0.74 11.14 0.52 8.37e-25 Corneal astigmatism; LIHC cis rs4638749 0.677 rs7595399 chr2:108835943 C/G cg25838818 chr2:108905173 SULT1C2 -0.4 -6.97 -0.35 1.69e-11 Blood pressure; LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.06 -0.31 3.67e-9 Total body bone mineral density; LIHC cis rs2404602 0.716 rs67418609 chr15:76627089 C/A cg03037974 chr15:76606532 NA 0.91 19.73 0.73 2.06e-58 Blood metabolite levels; LIHC cis rs1005277 0.579 rs2749612 chr10:38488610 G/A cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.27 -0.32 1.06e-9 Extrinsic epigenetic age acceleration; LIHC trans rs66887589 0.967 rs6844263 chr4:120433807 A/G cg25214090 chr10:38739885 LOC399744 0.38 6.19 0.32 1.74e-9 Diastolic blood pressure; LIHC cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg17971929 chr21:40555470 PSMG1 -0.83 -10.44 -0.49 2.45e-22 Cognitive function; LIHC cis rs17685 0.664 rs9801113 chr7:75792031 C/T cg01364799 chr7:75623366 TMEM120A -0.52 -7.74 -0.39 1.13e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6570726 0.905 rs421032 chr6:145827771 A/G cg23711669 chr6:146136114 FBXO30 0.56 10.32 0.49 6.24e-22 Lobe attachment (rater-scored or self-reported); LIHC trans rs2727020 0.576 rs61885308 chr11:49343363 G/A cg03929089 chr4:120376271 NA -0.46 -7.06 -0.36 9.12e-12 Coronary artery disease; LIHC trans rs2727020 0.595 rs10769583 chr11:49483193 G/A cg18944383 chr4:111397179 ENPEP 0.25 6.31 0.32 8.46e-10 Coronary artery disease; LIHC cis rs3770081 0.793 rs58186343 chr2:86218400 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -8.44 -0.42 8.84e-16 Facial emotion recognition (sad faces); LIHC cis rs12586317 0.547 rs10145723 chr14:35460954 G/A cg05294307 chr14:35346193 BAZ1A -0.49 -7.4 -0.37 1.04e-12 Psoriasis; LIHC cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg18230493 chr5:56204884 C5orf35 -0.44 -6.16 -0.32 2.08e-9 Initial pursuit acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22098324 chr2:232645906 PDE6D -0.36 -6.09 -0.31 3.02e-9 Cognitive function; LIHC cis rs6750047 0.625 rs59363818 chr2:38261973 A/C cg07380506 chr2:38303506 CYP1B1 -0.59 -7.45 -0.37 7.81e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs7474896 0.583 rs12776092 chr10:38015795 G/C cg25427524 chr10:38739819 LOC399744 -0.5 -7.4 -0.37 1.08e-12 Obesity (extreme); LIHC cis rs61990749 0.597 rs176955 chr14:78181220 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.2 0.48 1.72e-21 Fibroblast growth factor basic levels; LIHC trans rs4566357 0.521 rs78411533 chr2:227910807 G/A cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.6e-9 Coronary artery disease; LIHC cis rs7772486 0.875 rs10457792 chr6:146412415 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.73 0.3 2.26e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6840360 0.615 rs6535816 chr4:152614264 T/C cg22705602 chr4:152727874 NA -0.35 -7.2 -0.36 3.86e-12 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.680 rs11777459 chr8:58044241 A/T cg20607798 chr8:58055168 NA 0.44 5.82 0.3 1.34e-8 Developmental language disorder (linguistic errors); LIHC cis rs636291 0.517 rs55935829 chr1:10540926 A/T cg17425144 chr1:10567563 PEX14 0.53 10.14 0.48 2.59e-21 Prostate cancer; LIHC cis rs151997 1.000 rs152817 chr5:50230879 T/A cg06027927 chr5:50259733 NA -0.57 -7.71 -0.38 1.38e-13 Callous-unemotional behaviour; LIHC cis rs2180341 1.000 rs6569482 chr6:127631371 C/T cg24812749 chr6:127587940 RNF146 1.07 16.09 0.66 9.4e-44 Breast cancer; LIHC cis rs317689 0.690 rs317630 chr12:69637847 T/C cg20891283 chr12:69753455 YEATS4 0.48 6.72 0.34 7.41e-11 Response to diuretic therapy; LIHC cis rs273218 0.568 rs1644814 chr5:53365452 C/T ch.5.1024479R chr5:53302184 ARL15 0.56 9.07 0.44 9.37e-18 Migraine; LIHC cis rs6690583 0.623 rs1371143 chr1:85455532 C/T cg22153463 chr1:85462885 MCOLN2 0.49 6.07 0.31 3.44e-9 Serum sulfate level; LIHC cis rs950169 1.000 rs950169 chr15:84706461 C/T cg17507749 chr15:85114479 UBE2QP1 0.74 7.41 0.37 9.83e-13 Schizophrenia; LIHC cis rs17021463 0.807 rs6532480 chr4:95277038 T/C cg11021082 chr4:95130006 SMARCAD1 0.41 7.26 0.37 2.66e-12 Testicular germ cell tumor; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg07133347 chr1:107600762 PRMT6 0.45 6.63 0.34 1.3e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4713118 0.527 rs9461433 chr6:28095172 C/T cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Parkinson's disease; LIHC cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg21724239 chr8:58056113 NA 0.56 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs7826238 0.566 rs2945886 chr8:8148270 C/G cg15556689 chr8:8085844 FLJ10661 0.47 7.84 0.39 5.95e-14 Systolic blood pressure; LIHC cis rs1997103 1.000 rs6958664 chr7:55404958 T/G cg17469321 chr7:55412551 NA 0.48 7.09 0.36 7.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs933688 1.000 rs10474353 chr5:90732285 A/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.87 18.06 0.7 1.12e-51 Smoking behavior; LIHC cis rs9457247 1.000 rs394522 chr6:167398071 A/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.12 -0.52 9.74e-25 Crohn's disease; LIHC cis rs9399135 0.967 rs12661423 chr6:135349570 C/T cg22676075 chr6:135203613 NA 0.42 6.49 0.33 3.02e-10 Red blood cell count; LIHC cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg05564831 chr3:52568323 NT5DC2 0.38 5.98 0.31 5.78e-9 Bipolar disorder; LIHC cis rs9640161 0.830 rs35635199 chr7:150063342 C/T cg10018233 chr7:150070692 REPIN1 0.69 12.39 0.56 2.33e-29 Blood protein levels;Circulating chemerin levels; LIHC cis rs2576037 0.583 rs501062 chr18:44411135 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -7.08 -0.36 8.41e-12 Personality dimensions; LIHC cis rs16958440 0.867 rs75934126 chr18:44679781 T/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs2070488 0.804 rs4678605 chr3:38444489 T/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.73 11.9 0.54 1.51e-27 Electrocardiographic conduction measures; LIHC cis rs2075371 0.932 rs2241333 chr7:133970750 C/T cg11752832 chr7:134001865 SLC35B4 0.49 7.48 0.37 6.38e-13 Mean platelet volume; LIHC trans rs970548 0.606 rs12355888 chr10:45931564 G/T cg14222797 chr10:16859974 RSU1 -0.56 -6.07 -0.31 3.4e-9 Total cholesterol levels;Cholesterol, total;HDL cholesterol;HDL cholesterol levels; LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.46 6.52 0.33 2.58e-10 Lymphocyte counts; LIHC cis rs763121 0.853 rs3761454 chr22:39066820 C/T cg06022373 chr22:39101656 GTPBP1 0.64 11.16 0.52 7.35e-25 Menopause (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14230542 chr1:110577941 FAM40A 0.44 6.38 0.33 5.72e-10 Cognitive function; LIHC cis rs13064411 0.696 rs2129434 chr3:113138763 A/C cg18753928 chr3:113234510 CCDC52 -0.41 -5.74 -0.3 2.08e-8 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs9910055 0.530 rs2269906 chr17:42294337 G/T cg19774624 chr17:42201019 HDAC5 0.57 7.99 0.4 2.02e-14 Total body bone mineral density; LIHC trans rs2243480 1.000 rs55895244 chr7:65387678 C/G cg10756647 chr7:56101905 PSPH 1.09 13.54 0.59 9.78e-34 Diabetic kidney disease; LIHC cis rs13088318 0.504 rs535173 chr3:101055424 T/C cg19452782 chr3:101232218 SENP7 -0.39 -5.9 -0.3 8.8e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4908768 0.906 rs12117910 chr1:8556953 A/C cg25722041 chr1:8623473 RERE 0.41 5.85 0.3 1.18e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs12086130 0.892 rs72904790 chr1:51415652 T/C cg07174182 chr1:51127561 FAF1 -0.72 -8.24 -0.41 3.62e-15 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs644799 0.562 rs1313288 chr11:95520695 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.64 9.36 0.45 1.06e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.29e-12 Bipolar disorder; LIHC cis rs9916302 0.851 rs9904919 chr17:37556431 G/C cg03013999 chr17:37608204 MED1 -0.35 -5.79 -0.3 1.62e-8 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03100511 chr19:49173757 SEC1;NTN5 0.37 6.12 0.31 2.57e-9 Pancreatic cancer; LIHC trans rs3213545 0.659 rs2259690 chr12:121457914 T/G cg01148741 chr2:96811453 DUSP2 -0.39 -6.16 -0.32 2.08e-9 Subjective well-being;Cardiovascular disease risk factors; LIHC trans rs8002861 0.935 rs7318147 chr13:44445153 C/G cg12578287 chr13:42846195 AKAP11 0.48 6.62 0.34 1.39e-10 Leprosy; LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg02782426 chr3:40428986 ENTPD3 -0.35 -6.48 -0.33 3.13e-10 Renal cell carcinoma; LIHC cis rs2033908 0.620 rs1371753 chr11:12853703 G/A cg25843174 chr11:12811716 TEAD1 -0.34 -7.73 -0.39 1.18e-13 Sitting height ratio; LIHC cis rs6456156 0.846 rs10946211 chr6:167515489 G/A cg23791538 chr6:167370224 RNASET2 0.4 6.45 0.33 3.84e-10 Primary biliary cholangitis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03621406 chr19:9930365 FBXL12 -0.51 -7.01 -0.35 1.25e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05947499 chr12:113704091 TPCN1 0.45 6.92 0.35 2.24e-11 Longevity; LIHC cis rs6912958 0.781 rs1051148 chr6:88221892 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.07 -0.4 1.22e-14 Monocyte percentage of white cells; LIHC cis rs34375054 0.526 rs34764657 chr12:125679639 A/G cg25124228 chr12:125621409 AACS -0.45 -7.84 -0.39 5.97e-14 Post bronchodilator FEV1/FVC ratio; LIHC cis rs2303759 0.958 rs1465697 chr19:49837246 C/T cg24324837 chr19:49891574 CCDC155 0.38 5.88 0.3 9.59e-9 Multiple sclerosis; LIHC cis rs970821 0.667 rs1985668 chr8:124742952 T/A cg00283535 chr8:124749564 ANXA13 0.45 8.08 0.4 1.12e-14 Breast cancer; LIHC cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg07308232 chr7:1071921 C7orf50 -0.54 -8.85 -0.43 4.75e-17 Longevity;Endometriosis; LIHC cis rs79149102 0.579 rs12594117 chr15:75323648 C/G cg17294928 chr15:75287854 SCAMP5 -0.48 -6.19 -0.32 1.71e-9 Lung cancer; LIHC cis rs4759375 1.000 rs4759375 chr12:123796238 C/T cg00376283 chr12:123451042 ABCB9 -0.54 -6.7 -0.34 8.39e-11 HDL cholesterol; LIHC cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg11494091 chr17:61959527 GH2 -0.52 -9.89 -0.47 1.95e-20 Prudent dietary pattern; LIHC cis rs7572733 0.534 rs1518363 chr2:198810131 C/T cg00792783 chr2:198669748 PLCL1 0.46 6.81 0.35 4.49e-11 Dermatomyositis; LIHC cis rs4746818 0.688 rs951718 chr10:70928044 A/G cg11621586 chr10:70884670 VPS26A 0.87 14.21 0.61 2.48e-36 Left atrial antero-posterior diameter; LIHC cis rs1707322 0.717 rs12023439 chr1:46104636 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.45 0.37 7.63e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1577917 0.958 rs11754330 chr6:86455070 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.09 -0.51 1.29e-24 Response to antipsychotic treatment; LIHC cis rs9291683 0.609 rs12500810 chr4:10031068 G/A cg11266682 chr4:10021025 SLC2A9 0.35 7.46 0.37 7.3e-13 Bone mineral density; LIHC cis rs903552 0.736 rs11858491 chr15:102007456 C/T cg19295451 chr15:102010161 PCSK6 0.53 7.6 0.38 2.91e-13 Diabetic kidney disease; LIHC cis rs9522267 0.535 rs11069900 chr13:112233285 G/A cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs8038465 0.615 rs62004618 chr15:73962164 A/G cg15420318 chr15:73925796 NPTN 0.44 6.81 0.35 4.35e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7654585 0.645 rs6828416 chr4:25933273 C/T cg10409131 chr4:25915609 C4orf52 0.57 9.08 0.44 8.65e-18 Obesity-related traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09011732 chr2:74730507 LOC151534;LBX2 -0.4 -6.36 -0.33 6.43e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs9457247 1.000 rs405553 chr6:167395058 A/G cg12798992 chr6:167411361 FGFR1OP 0.58 9.52 0.46 3.29e-19 Crohn's disease; LIHC cis rs1008375 0.966 rs3775923 chr4:17585625 T/C cg16339924 chr4:17578868 LAP3 0.59 7.64 0.38 2.23e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1577917 0.771 rs9362233 chr6:86358247 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.55 -0.56 5.78e-30 Response to antipsychotic treatment; LIHC cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg11301795 chr4:187892539 NA -0.26 -6.99 -0.35 1.44e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs8072100 0.840 rs11079774 chr17:45479706 C/G cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.87 -0.3 1.03e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2346177 0.519 rs1597040 chr2:46673903 C/T cg02822958 chr2:46747628 ATP6V1E2 0.47 7.11 0.36 6.71e-12 HDL cholesterol; LIHC cis rs77633900 0.772 rs75253262 chr15:76657124 G/A cg21673338 chr15:77095150 SCAPER -0.53 -6.15 -0.32 2.15e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs5758511 0.680 rs5758652 chr22:42612408 T/C cg20195005 chr22:42527684 CYP2D6 0.31 5.91 0.3 8.33e-9 Birth weight; LIHC trans rs11098499 0.775 rs67281037 chr4:120281157 G/C cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC trans rs459571 0.959 rs378740 chr9:136890876 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.61 -9.53 -0.46 3.01e-19 Platelet distribution width; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23187205 chr6:109416245 SESN1;C6orf182 0.47 6.63 0.34 1.33e-10 Pancreatic cancer; LIHC cis rs7903847 0.620 rs954149 chr10:99122936 G/A cg06359132 chr10:99160096 RRP12 -0.4 -6.04 -0.31 4.02e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2425143 1.000 rs1890470 chr20:34357008 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.53 -6.89 -0.35 2.64e-11 Blood protein levels; LIHC cis rs477692 0.699 rs509017 chr10:131367174 T/G cg05714579 chr10:131428358 MGMT 0.42 6.82 0.35 4.24e-11 Response to temozolomide; LIHC cis rs10792665 0.547 rs10736755 chr11:82559433 C/T cg24227371 chr11:82718527 RAB30 -0.26 -6.25 -0.32 1.19e-9 Obesity-related traits; LIHC cis rs7520050 0.807 rs5021934 chr1:46109304 A/G cg24296786 chr1:45957014 TESK2 0.39 5.8 0.3 1.48e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg25894440 chr7:65020034 NA -0.52 -5.79 -0.3 1.6e-8 Diabetic kidney disease; LIHC cis rs769267 0.930 rs3794990 chr19:19610030 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.87 0.3 1.05e-8 Tonsillectomy; LIHC cis rs13108904 0.818 rs3775099 chr4:1232510 C/G cg13395646 chr4:1353034 KIAA1530 -0.56 -7.82 -0.39 6.75e-14 Obesity-related traits; LIHC cis rs4638749 0.627 rs4676185 chr2:108841908 G/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg24879335 chr3:133465180 TF 0.29 6.39 0.33 5.4e-10 Iron status biomarkers; LIHC cis rs9905704 0.624 rs34718875 chr17:57072461 G/A cg05425664 chr17:57184151 TRIM37 -0.44 -6.24 -0.32 1.29e-9 Testicular germ cell tumor; LIHC cis rs950169 0.845 rs4502182 chr15:84923520 A/G cg12863693 chr15:85201151 NMB 0.41 5.83 0.3 1.27e-8 Schizophrenia; LIHC cis rs4684776 0.676 rs3732941 chr3:11304575 A/G cg00170343 chr3:11313890 ATG7 -0.49 -6.78 -0.34 5.3e-11 Small vessel stroke; LIHC cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg03517284 chr6:25882590 NA 0.49 7.06 0.36 9.06e-12 Blood metabolite levels; LIHC cis rs9457247 1.000 rs2149085 chr6:167371110 T/C cg23791538 chr6:167370224 RNASET2 0.69 11.65 0.53 1.22e-26 Crohn's disease; LIHC cis rs919433 0.889 rs12693816 chr2:198208420 T/A cg03934865 chr2:198174659 NA -0.56 -8.67 -0.42 1.74e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg03395511 chr6:291903 DUSP22 -0.5 -6.61 -0.34 1.44e-10 Menopause (age at onset); LIHC cis rs875971 1.000 rs10244498 chr7:66116056 A/G cg18252515 chr7:66147081 NA -0.44 -6.26 -0.32 1.17e-9 Aortic root size; LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.66e-17 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03337784 chr13:41768818 KBTBD7 0.39 6.25 0.32 1.2e-9 Cognitive function; LIHC cis rs2180341 0.889 rs9321074 chr6:127618019 G/A cg27446573 chr6:127587934 RNF146 1.03 15.95 0.65 3.18e-43 Breast cancer; LIHC cis rs9309473 1.000 rs2140195 chr2:73702344 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.79 -0.34 4.95e-11 Metabolite levels; LIHC cis rs10791097 0.694 rs2236711 chr11:130739284 G/A cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9916302 0.904 rs6503503 chr17:37514373 G/A cg00129232 chr17:37814104 STARD3 0.38 6.11 0.31 2.67e-9 Glomerular filtration rate (creatinine); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25329296 chr4:113486062 C4orf21 0.44 6.56 0.33 2e-10 Longevity; LIHC cis rs12887734 0.524 rs4900599 chr14:104283444 G/T cg08213375 chr14:104286397 PPP1R13B 0.53 9.17 0.44 4.64e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs9790314 1.000 rs163328 chr3:161073599 A/G cg03342759 chr3:160939853 NMD3 -0.67 -7.96 -0.4 2.53e-14 Morning vs. evening chronotype; LIHC cis rs801193 1.000 rs1553610 chr7:66197233 T/C cg14393609 chr7:65229607 NA 0.37 5.71 0.3 2.42e-8 Aortic root size; LIHC cis rs6964587 0.773 rs13223564 chr7:91932666 A/G cg17063962 chr7:91808500 NA 0.98 17.0 0.68 2.01e-47 Breast cancer; LIHC cis rs2635047 1.000 rs2684825 chr18:44666415 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.46 5.98 0.31 5.68e-9 Educational attainment; LIHC cis rs7914558 0.966 rs4532960 chr10:104667406 C/T cg15744005 chr10:104629667 AS3MT -0.4 -9.05 -0.44 1.08e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg02353165 chr6:42928485 GNMT 0.76 11.98 0.54 7.16e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7772486 0.875 rs2777484 chr6:146334162 A/G cg23711669 chr6:146136114 FBXO30 0.6 10.67 0.5 3.77e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs9811920 0.638 rs793474 chr3:99544380 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.8 0.3 1.51e-8 Axial length; LIHC cis rs422249 0.512 rs174583 chr11:61609750 A/G cg27386326 chr11:61587980 NA -0.63 -13.48 -0.59 1.69e-33 Trans fatty acid levels; LIHC cis rs10489202 0.608 rs10918826 chr1:168075316 C/T cg24449463 chr1:168025552 DCAF6 -0.54 -8.36 -0.41 1.57e-15 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06745235 chr1:180471494 ACBD6 0.44 6.71 0.34 8.24e-11 Pancreatic cancer; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg22903471 chr2:27725779 GCKR -0.52 -8.98 -0.44 1.79e-17 Total body bone mineral density; LIHC cis rs1506636 0.525 rs7812023 chr7:123260228 C/T cg03229431 chr7:123269106 ASB15 -0.56 -10.09 -0.48 3.98e-21 Plateletcrit;Platelet count; LIHC cis rs6690583 0.623 rs111687161 chr1:85443533 A/G cg22153463 chr1:85462885 MCOLN2 0.52 6.24 0.32 1.32e-9 Serum sulfate level; LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.49 -0.38 6e-13 Lymphocyte counts; LIHC cis rs2832191 0.716 rs1888439 chr21:30454457 A/G cg08807101 chr21:30365312 RNF160 0.79 11.85 0.54 2.34e-27 Dental caries; LIHC cis rs1434579 1.000 rs1434579 chr19:44932972 C/T cg15540054 chr19:45004280 ZNF180 0.55 7.36 0.37 1.4e-12 Tuberculosis; LIHC cis rs4407350 0.756 rs131154 chr22:44890845 C/G cg11695653 chr22:44894386 LDOC1L -0.38 -6.49 -0.33 3.02e-10 Intelligence (multi-trait analysis); LIHC cis rs67478160 0.619 rs1040813 chr14:104306696 T/C cg08213375 chr14:104286397 PPP1R13B 0.64 12.29 0.55 5.2e-29 Schizophrenia; LIHC cis rs10752881 0.935 rs10911197 chr1:182995399 T/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Colorectal cancer; LIHC cis rs796364 0.806 rs34510964 chr2:201010676 C/G cg19045956 chr2:200819837 C2orf60;C2orf47 -0.37 -5.81 -0.3 1.43e-8 Schizophrenia; LIHC cis rs2273156 1.000 rs17102970 chr14:35480569 T/G cg16230307 chr14:35515116 FAM177A1 -0.41 -5.99 -0.31 5.17e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 6.02e-12 Diabetic kidney disease; LIHC cis rs17685 0.725 rs2302436 chr7:75676988 A/T cg04610667 chr7:75704037 NA 0.35 6.12 0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs727505 0.954 rs66526112 chr7:124504074 C/A cg23710748 chr7:124431027 NA -0.32 -5.78 -0.3 1.66e-8 Lewy body disease; LIHC cis rs7520050 0.966 rs12411269 chr1:46271052 C/T cg03146154 chr1:46216737 IPP -0.4 -6.55 -0.33 2.11e-10 Red blood cell count;Reticulocyte count; LIHC cis rs4243830 0.850 rs4908912 chr1:6599558 A/C cg22792644 chr1:6614718 TAS1R1;NOL9 -0.83 -9.15 -0.44 5.17e-18 Body mass index; LIHC cis rs1707322 0.717 rs3014246 chr1:46086077 C/T cg24296786 chr1:45957014 TESK2 0.4 5.73 0.3 2.26e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7615952 0.932 rs13065725 chr3:125632289 C/A cg05084668 chr3:125655381 ALG1L -0.6 -8.49 -0.42 6.24e-16 Blood pressure (smoking interaction); LIHC trans rs1814175 0.817 rs4881623 chr11:49804991 C/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.51 -0.79 2.04e-73 Height; LIHC cis rs1003719 0.715 rs762139 chr21:38568475 A/T cg10648535 chr21:38446584 PIGP;TTC3 0.66 9.53 0.46 2.94e-19 Eye color traits; LIHC cis rs7100689 0.646 rs7098045 chr10:82123856 G/C cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg25894440 chr7:65020034 NA -0.53 -6.17 -0.32 1.93e-9 Diabetic kidney disease; LIHC cis rs77633900 0.614 rs2454453 chr15:76913976 T/A cg21673338 chr15:77095150 SCAPER -0.49 -7.21 -0.36 3.68e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs1997103 1.000 rs6976824 chr7:55396115 A/C cg17469321 chr7:55412551 NA 0.47 6.82 0.35 4.03e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs16958440 0.581 rs11873880 chr18:44692465 T/C cg17192377 chr18:44677553 HDHD2 0.71 7.79 0.39 8.32e-14 Sitting height ratio; LIHC cis rs7737355 0.853 rs26005 chr5:130988029 A/G cg06307176 chr5:131281290 NA 0.4 5.84 0.3 1.23e-8 Life satisfaction; LIHC cis rs6089584 1.000 rs6089583 chr20:60563624 G/A cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22161983 chr8:103818636 NA 0.38 6.05 0.31 3.72e-9 Pancreatic cancer; LIHC cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.06 0.31 3.6e-9 Menopause (age at onset); LIHC cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.56 8.74 0.43 1.07e-16 Schizophrenia; LIHC cis rs4845570 1.000 rs1054479 chr1:151746079 A/T cg07092448 chr1:151763213 TDRKH -0.72 -7.97 -0.4 2.33e-14 Coronary artery disease; LIHC cis rs7587476 0.784 rs34112702 chr2:215696002 A/G cg04530015 chr2:215796436 ABCA12 -0.39 -6.39 -0.33 5.58e-10 Neuroblastoma; LIHC cis rs3770081 1.000 rs2303339 chr2:86346180 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 -0.44 -5.95 -0.31 6.65e-9 Facial emotion recognition (sad faces); LIHC cis rs12908161 1.000 rs11637142 chr15:85295927 A/G cg17507749 chr15:85114479 UBE2QP1 0.61 6.95 0.35 1.81e-11 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17061595 chr4:1245206 C4orf42 0.4 6.08 0.31 3.12e-9 Longevity; LIHC cis rs7923452 0.688 rs117895480 chr10:30788921 A/G cg25182066 chr10:30743637 MAP3K8 0.47 6.16 0.32 2.03e-9 Itch intensity from mosquito bite; LIHC cis rs9911578 1.000 rs12936058 chr17:57017420 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.79 0.69 1.4e-50 Intelligence (multi-trait analysis); LIHC cis rs1144333 0.850 rs1251273 chr1:76288617 A/G cg03433033 chr1:76189801 ACADM -0.56 -8.54 -0.42 4.51e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg16434002 chr17:42200994 HDAC5 0.51 7.38 0.37 1.18e-12 Total body bone mineral density; LIHC cis rs35110281 0.563 rs162371 chr21:44931489 G/T cg21573476 chr21:45109991 RRP1B -0.47 -8.7 -0.43 1.4e-16 Mean corpuscular volume; LIHC cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC cis rs644799 1.000 rs617999 chr11:95589935 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.69 0.46 9.15e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs16958440 0.708 rs57468764 chr18:44624856 T/C cg17192377 chr18:44677553 HDHD2 0.52 6.53 0.33 2.38e-10 Sitting height ratio; LIHC cis rs11098499 0.954 rs10005644 chr4:120298477 T/C cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs2153535 0.580 rs7748455 chr6:8453625 C/T cg21535247 chr6:8435926 SLC35B3 0.63 8.45 0.42 8.36e-16 Motion sickness; LIHC cis rs34779708 0.897 rs4934716 chr10:35369299 A/G cg04310649 chr10:35416472 CREM -0.42 -5.78 -0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg07414643 chr4:187882934 NA 0.23 5.97 0.31 6.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2439831 0.867 rs3213991 chr15:43670280 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.92 17.31 0.68 1.2e-48 Lung cancer in ever smokers; LIHC cis rs6964587 0.967 rs10280620 chr7:91582183 C/G cg17063962 chr7:91808500 NA -1.02 -19.48 -0.73 2.17e-57 Breast cancer; LIHC cis rs9326248 0.520 rs6589602 chr11:117037065 T/C cg26566898 chr11:117069891 TAGLN 0.39 6.05 0.31 3.79e-9 Blood protein levels; LIHC cis rs67460515 0.596 rs35589595 chr3:160930984 G/A cg03342759 chr3:160939853 NMD3 -0.61 -9.1 -0.44 7.44e-18 Parkinson's disease; LIHC cis rs3740540 0.507 rs897292 chr10:126290035 A/G cg04949429 chr10:126290192 LHPP 0.45 7.36 0.37 1.37e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs9611565 0.569 rs6002328 chr22:41710034 T/C cg03806693 chr22:41940476 POLR3H -0.73 -8.71 -0.43 1.34e-16 Vitiligo; LIHC cis rs7208859 0.573 rs8064686 chr17:29134839 C/T cg14067834 chr17:29058358 SUZ12P 0.71 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9486719 1.000 rs2472880 chr6:96860130 G/A cg06623918 chr6:96969491 KIAA0776 0.72 6.94 0.35 1.94e-11 Migraine;Coronary artery disease; LIHC cis rs4908760 0.860 rs11121202 chr1:8639357 T/C cg20416874 chr1:8611966 RERE -0.65 -12.94 -0.57 1.91e-31 Vitiligo; LIHC cis rs2204008 0.591 rs11495396 chr12:38380182 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.36 0.41 1.56e-15 Bladder cancer; LIHC cis rs7940866 0.801 rs10894288 chr11:130808679 T/C cg12179176 chr11:130786555 SNX19 0.64 9.52 0.46 3.19e-19 Schizophrenia; LIHC cis rs10847980 0.590 rs2292131 chr12:123332354 C/T cg22842854 chr12:123319900 HIP1R 0.92 10.44 0.49 2.49e-22 Adiponectin levels; LIHC trans rs11722228 0.508 rs3796825 chr4:10092879 T/A cg26043149 chr18:55253948 FECH 0.95 13.92 0.6 3.3e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs1005277 0.563 rs2505216 chr10:38482830 T/C cg00409905 chr10:38381863 ZNF37A -0.57 -9.48 -0.46 4.29e-19 Extrinsic epigenetic age acceleration; LIHC cis rs10870270 1.000 rs11146324 chr10:133767445 A/C cg08754478 chr10:133766260 PPP2R2D -0.54 -8.03 -0.4 1.58e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg24531977 chr5:56204891 C5orf35 -0.69 -9.87 -0.47 2.26e-20 Initial pursuit acceleration; LIHC cis rs7552404 0.960 rs12085123 chr1:76149749 G/A cg10523679 chr1:76189770 ACADM 0.66 9.13 0.44 6.1e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4423214 0.802 rs4402322 chr11:71184015 C/G cg05163923 chr11:71159392 DHCR7 -0.6 -7.9 -0.39 3.79e-14 Vitamin D levels; LIHC cis rs7208859 0.510 rs216402 chr17:28917126 A/T cg13385521 chr17:29058706 SUZ12P 0.69 6.62 0.34 1.36e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs611744 0.967 rs595266 chr8:109193784 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04433306 chr7:129592730 UBE2H -0.46 -6.69 -0.34 9.13e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7208859 0.673 rs1347360 chr17:28914532 T/C cg14067834 chr17:29058358 SUZ12P 0.61 6.18 0.32 1.8e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs62179067 0.708 rs11901918 chr2:179940077 A/G cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs6586163 1.000 rs7097572 chr10:90753260 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.57 -8.42 -0.41 1.06e-15 Chronic lymphocytic leukemia; LIHC cis rs875971 0.862 rs2088655 chr7:65795711 T/C cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs35306767 0.668 rs72760914 chr10:1070952 A/G cg20503657 chr10:835505 NA 0.53 5.85 0.3 1.15e-8 Eosinophil percentage of granulocytes; LIHC cis rs4906332 0.966 rs7159665 chr14:103984616 C/T cg26031613 chr14:104095156 KLC1 -0.44 -5.97 -0.31 5.85e-9 Coronary artery disease; LIHC cis rs5758659 1.000 rs134900 chr22:42683343 C/G cg19513890 chr22:42538836 CYP2D7P1 -0.38 -7.26 -0.37 2.55e-12 Cognitive function; LIHC cis rs4474465 0.850 rs4482052 chr11:78263331 A/G cg27205649 chr11:78285834 NARS2 0.44 6.82 0.35 4.11e-11 Alzheimer's disease (survival time); LIHC cis rs950776 0.518 rs12910289 chr15:78822065 T/G cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs11800820 0.615 rs7513288 chr1:246661679 A/G cg16700716 chr1:246684329 NA -0.49 -8.15 -0.4 6.87e-15 Obesity-related traits; LIHC cis rs9457247 0.935 rs1187530 chr6:167376812 C/T cg23791538 chr6:167370224 RNASET2 0.69 11.76 0.54 4.7e-27 Crohn's disease; LIHC cis rs1577917 0.958 rs12191340 chr6:86521400 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -5.93 -0.31 7.32e-9 Response to antipsychotic treatment; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13735959 chr19:40949335 SERTAD3 -0.47 -6.1 -0.31 2.8e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1707322 1.000 rs785519 chr1:46568562 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.73 -0.34 7.29e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03050127 chr17:59413660 BCAS3 0.21 6.64 0.34 1.23e-10 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00399650 chr7:141402322 KIAA1147 0.45 6.7 0.34 8.51e-11 Pancreatic cancer; LIHC cis rs3806843 0.735 rs801168 chr5:140080298 A/G cg26395211 chr5:140044315 WDR55 0.41 5.97 0.31 6e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.46 -6.62 -0.34 1.42e-10 Lymphocyte counts; LIHC cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg23982607 chr1:1823379 GNB1 -0.7 -13.45 -0.59 2.07e-33 Body mass index; LIHC cis rs10751667 0.560 rs7924794 chr11:962745 A/T cg10932868 chr11:921992 NA 0.38 7.07 0.36 8.7e-12 Alzheimer's disease (late onset); LIHC cis rs4803468 0.967 rs3786553 chr19:41902746 T/G cg09537434 chr19:41945824 ATP5SL -0.99 -20.25 -0.74 1.8e-60 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19223106 chr19:58898630 RPS5 0.57 7.38 0.37 1.23e-12 Lung function (FEV1/FVC); LIHC cis rs9517320 0.534 rs61969451 chr13:99167654 A/T cg07423050 chr13:99094983 FARP1 -0.48 -8.23 -0.41 3.9e-15 Longevity; LIHC cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg03264133 chr6:25882463 NA -0.72 -9.03 -0.44 1.27e-17 Intelligence (multi-trait analysis); LIHC cis rs288342 0.832 rs288304 chr2:183653727 C/A cg02625481 chr2:183667124 NA -0.29 -6.1 -0.31 2.83e-9 Recurrent major depressive disorder; LIHC cis rs743757 1.000 rs2236964 chr3:50449062 C/G cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.52 -8.15 -0.4 6.93e-15 Diastolic blood pressure; LIHC cis rs1395 0.925 rs2580754 chr2:27398196 A/T cg23587288 chr2:27483067 SLC30A3 -0.29 -5.74 -0.3 2.08e-8 Blood metabolite levels; LIHC trans rs2579103 0.630 rs1222611 chr12:90709661 C/T cg07211377 chr9:34377402 KIAA1161 -0.48 -6.76 -0.34 6.1e-11 Body mass index; LIHC cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.86 0.3 1.11e-8 Menopause (age at onset); LIHC cis rs6674970 0.932 rs12569193 chr1:151115186 C/T cg03258749 chr1:151040405 MLLT11 -0.48 -7.48 -0.37 6.49e-13 Childhood ear infection; LIHC trans rs10506458 0.915 rs56321182 chr12:63392023 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.66 -0.5 4.34e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs903552 0.736 rs2132196 chr15:102007089 A/G cg19295451 chr15:102010161 PCSK6 -0.54 -7.6 -0.38 2.78e-13 Diabetic kidney disease; LIHC cis rs9733 0.596 rs12089989 chr1:150715782 G/A cg18016565 chr1:150552671 MCL1 0.54 10.69 0.5 3.32e-23 Tonsillectomy; LIHC cis rs295137 0.836 rs10804097 chr2:201104924 A/T cg23649088 chr2:200775458 C2orf69 0.48 6.65 0.34 1.19e-10 Asthma (bronchodilator response); LIHC cis rs7918232 0.941 rs1775350 chr10:27441973 C/T cg14240646 chr10:27532245 ACBD5 0.68 6.32 0.32 8.3e-10 Breast cancer; LIHC cis rs7617773 0.743 rs13081633 chr3:48357281 A/G cg11946769 chr3:48343235 NME6 0.91 11.33 0.52 1.81e-25 Coronary artery disease; LIHC cis rs8078723 0.510 rs3087852 chr17:38137364 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.71 12.91 0.57 2.52e-31 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2153535 0.580 rs7450817 chr6:8481421 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC cis rs7927592 0.913 rs6591340 chr11:68297636 A/G cg16797656 chr11:68205561 LRP5 0.52 8.18 0.4 5.51e-15 Total body bone mineral density; LIHC cis rs4808199 0.948 rs7259434 chr19:19428805 A/T cg20644253 chr19:19431407 KIAA0892;SF4 0.55 8.05 0.4 1.43e-14 Nonalcoholic fatty liver disease; LIHC cis rs9457247 1.000 rs408080 chr6:167392522 T/C cg07741184 chr6:167504864 NA 0.3 6.93 0.35 2.14e-11 Crohn's disease; LIHC cis rs7095607 0.521 rs2673792 chr10:69927959 T/A cg18986048 chr10:69913749 MYPN 0.48 7.07 0.36 8.82e-12 Lung function (FVC); LIHC cis rs7769051 0.711 rs9493435 chr6:133088205 A/G cg07930552 chr6:133119739 C6orf192 0.6 5.85 0.3 1.17e-8 Type 2 diabetes nephropathy; LIHC cis rs7552404 0.924 rs1146579 chr1:76209792 C/T cg10523679 chr1:76189770 ACADM -0.64 -9.61 -0.46 1.61e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs929354 0.742 rs2051877 chr7:157008813 A/T cg05182265 chr7:156933206 UBE3C -0.33 -6.28 -0.32 1.05e-9 Body mass index; LIHC cis rs12477438 0.520 rs2309581 chr2:99784292 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.16 -18.52 -0.71 1.54e-53 Chronic sinus infection; LIHC cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg24549020 chr5:56110836 MAP3K1 0.51 6.61 0.34 1.5e-10 Initial pursuit acceleration; LIHC cis rs600806 0.813 rs4970760 chr1:109985439 A/G cg08911820 chr1:110026001 ATXN7L2 -0.58 -6.99 -0.35 1.45e-11 Intelligence (multi-trait analysis); LIHC cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg10295955 chr4:187884368 NA -0.95 -21.95 -0.76 2.98e-67 Lobe attachment (rater-scored or self-reported); LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg13470557 chr20:61431876 C20orf20 0.45 6.47 0.33 3.42e-10 Hip circumference; LIHC cis rs4474465 1.000 rs2063729 chr11:78185969 C/T cg02023728 chr11:77925099 USP35 0.32 5.82 0.3 1.34e-8 Alzheimer's disease (survival time); LIHC cis rs7617773 0.925 rs35942721 chr3:48173069 C/T cg11946769 chr3:48343235 NME6 0.77 9.23 0.45 2.99e-18 Coronary artery disease; LIHC cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.45 -6.23 -0.32 1.38e-9 Colorectal cancer; LIHC cis rs2067615 0.579 rs12424114 chr12:107144328 A/G cg15890332 chr12:107067104 RFX4 0.26 6.02 0.31 4.61e-9 Heart rate; LIHC cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg24531977 chr5:56204891 C5orf35 -0.68 -9.78 -0.47 4.54e-20 Initial pursuit acceleration; LIHC cis rs4684776 0.867 rs13084898 chr3:11334276 C/T cg00170343 chr3:11313890 ATG7 -0.53 -7.29 -0.37 2.2e-12 Small vessel stroke; LIHC cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg27170947 chr2:26402098 FAM59B -0.63 -7.67 -0.38 1.76e-13 Gut microbiome composition (summer); LIHC cis rs7044106 0.791 rs735109 chr9:123488879 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.77 12.66 0.56 2.25e-30 Hip circumference adjusted for BMI; LIHC trans rs1814175 0.817 rs1851858 chr11:49855638 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.43 -0.78 4.16e-73 Height; LIHC cis rs7554547 0.667 rs4846072 chr1:11950391 T/C cg07603449 chr1:11986842 KIAA2013 -0.36 -6.07 -0.31 3.32e-9 Nonsyndromic cleft lip with cleft palate; LIHC cis rs2153535 0.542 rs915354 chr6:8440357 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.51 0.53 3.97e-26 Motion sickness; LIHC cis rs2197308 0.619 rs4002730 chr12:37876400 T/C cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs35110281 0.774 rs2838327 chr21:45018566 A/C cg21573476 chr21:45109991 RRP1B -0.52 -9.8 -0.47 3.7799999999999997e-20 Mean corpuscular volume; LIHC cis rs1538970 0.816 rs9727262 chr1:45998579 T/G cg05343316 chr1:45956843 TESK2 0.62 8.71 0.43 1.36e-16 Platelet count; LIHC cis rs9814567 1.000 rs9856693 chr3:134306913 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.45e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4423214 0.840 rs1790339 chr11:71182761 C/A cg05163923 chr11:71159392 DHCR7 -0.59 -7.89 -0.39 4.03e-14 Vitamin D levels; LIHC cis rs1005277 0.579 rs1780139 chr10:38503018 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.3 -0.32 9.29e-10 Extrinsic epigenetic age acceleration; LIHC cis rs12744310 0.887 rs12043581 chr1:41788265 C/T cg03962019 chr1:41807865 NA 0.36 5.86 0.3 1.08e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs12765878 1.000 rs11191843 chr10:105648651 G/C cg11005552 chr10:105648138 OBFC1 0.37 5.86 0.3 1.12e-8 Coronary artery disease; LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg13409248 chr3:40428643 ENTPD3 0.5 8.44 0.42 9.3e-16 Renal cell carcinoma; LIHC cis rs6500602 0.702 rs3789038 chr16:4546586 C/G cg04083430 chr16:4736063 MGRN1 0.44 5.96 0.31 6.25e-9 Schizophrenia; LIHC cis rs5758511 0.680 rs739147 chr22:42671066 T/G cg20195005 chr22:42527684 CYP2D6 0.31 5.82 0.3 1.37e-8 Birth weight; LIHC cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg04267008 chr7:1944627 MAD1L1 -0.63 -10.27 -0.49 9.5e-22 Bipolar disorder and schizophrenia; LIHC cis rs10097731 0.901 rs10464931 chr8:82042664 A/G cg25230327 chr8:82042993 NA 0.52 7.08 0.36 8.34e-12 Serum total protein level; LIHC cis rs2204008 0.774 rs3910796 chr12:38230660 G/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC trans rs6437061 0.835 rs2853361 chr2:233120923 A/G cg19760917 chr1:2411643 PLCH2 -0.41 -6.41 -0.33 4.69e-10 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs57590327 0.503 rs2049415 chr3:81901887 A/T cg07356753 chr3:81810745 GBE1 -0.52 -7.88 -0.39 4.46e-14 Extraversion; LIHC cis rs950776 0.684 rs61012457 chr15:78865694 C/G cg06917634 chr15:78832804 PSMA4 0.71 9.58 0.46 2.08e-19 Sudden cardiac arrest; LIHC cis rs6500602 0.727 rs2058811 chr16:4575162 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.42 5.71 0.3 2.45e-8 Schizophrenia; LIHC cis rs6450176 0.564 rs34360866 chr5:53332737 A/G ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.5 -0.59 1.4e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs950776 0.518 rs12591557 chr15:78811732 A/G cg06917634 chr15:78832804 PSMA4 0.9 13.35 0.59 5.41e-33 Sudden cardiac arrest; LIHC trans rs11098499 0.863 rs7695620 chr4:120452776 G/A cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04305677 chr7:2281541 NUDT1;FTSJ2 -0.55 -7.19 -0.36 4.14e-12 Systolic blood pressure; LIHC cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.23 0.55 8.88e-29 Alzheimer's disease; LIHC cis rs559928 0.606 rs56207008 chr11:63883215 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.4 0.37 1.04e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs990171 0.506 rs4141632 chr2:102757139 A/G cg22835712 chr2:102737379 NA 0.56 8.76 0.43 8.96e-17 Lymphocyte counts; LIHC cis rs2153535 0.542 rs9393012 chr6:8439809 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.67 0.53 1.03e-26 Motion sickness; LIHC cis rs1799949 0.894 rs36062488 chr17:41337472 C/T cg23758822 chr17:41437982 NA -0.91 -17.09 -0.68 8.66e-48 Menopause (age at onset); LIHC cis rs4975709 0.610 rs1531994 chr5:1859297 T/C cg14773178 chr5:1868261 NA 0.26 6.74 0.34 6.56e-11 Cardiovascular disease risk factors; LIHC cis rs711245 0.572 rs3821150 chr2:36795233 G/A cg09467607 chr2:36825704 FEZ2 0.48 7.1 0.36 7.04e-12 Height; LIHC cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg10935138 chr17:73851978 WBP2 0.79 10.5 0.49 1.5e-22 Psoriasis; LIHC cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg13393036 chr8:95962371 TP53INP1 -0.4 -9.28 -0.45 2.06e-18 Type 2 diabetes; LIHC cis rs6690583 0.623 rs1371142 chr1:85455373 A/T cg22153463 chr1:85462885 MCOLN2 0.49 5.91 0.3 8.45e-9 Serum sulfate level; LIHC cis rs2153535 0.580 rs2327061 chr6:8447231 G/C cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.21e-26 Motion sickness; LIHC cis rs12079745 0.623 rs2982468 chr1:169090971 A/T cg09363564 chr1:169337483 NME7;BLZF1 -0.63 -6.46 -0.33 3.51e-10 QT interval; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs3736485 0.966 rs11634180 chr15:51895757 G/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.29 -0.32 9.52e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs4073582 0.595 rs9326370 chr11:65992008 A/G cg09254047 chr11:66045564 CNIH2 -0.39 -5.8 -0.3 1.51e-8 Gout; LIHC cis rs801193 1.000 rs7789184 chr7:66210195 A/T cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.5e-9 Aortic root size; LIHC cis rs986417 1.000 rs713336 chr14:60974958 T/G cg27398547 chr14:60952738 C14orf39 0.85 9.85 0.47 2.61e-20 Gut microbiota (bacterial taxa); LIHC cis rs8067354 0.574 rs1292033 chr17:57990597 A/T cg02344993 chr17:57696989 CLTC 0.66 10.44 0.49 2.57e-22 Hemoglobin concentration; LIHC trans rs2727020 0.681 rs2866362 chr11:49379316 A/G cg15704280 chr7:45808275 SEPT13 -0.93 -17.77 -0.69 1.67e-50 Coronary artery disease; LIHC cis rs11039389 1 rs11039389 chr11:47796062 T/C cg20135002 chr11:47629003 NA -0.54 -9.21 -0.45 3.48e-18 Neuroticism; LIHC cis rs916888 0.738 rs199515 chr17:44856641 C/G cg15921436 chr17:44337874 NA -0.61 -6.53 -0.33 2.44e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10791097 0.609 rs3751039 chr11:130773076 A/G cg22079354 chr11:130786696 SNX19 -0.46 -6.9 -0.35 2.52e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2455601 0.882 rs10840139 chr11:8894838 T/G cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -5.98 -0.31 5.55e-9 Schizophrenia; LIHC cis rs60871478 0.592 rs4275123 chr7:857352 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.54 -6.11 -0.31 2.78e-9 Cerebrospinal P-tau181p levels; LIHC cis rs7528419 0.927 rs660240 chr1:109817838 T/C cg06804625 chr1:109812012 CELSR2 -0.41 -5.94 -0.31 6.91e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs34375054 0.624 rs7132026 chr12:125678096 A/G cg25124228 chr12:125621409 AACS 0.43 7.17 0.36 4.72e-12 Post bronchodilator FEV1/FVC ratio; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24656492 chr10:70940659 SUPV3L1 0.46 6.08 0.31 3.25e-9 Pancreatic cancer; LIHC cis rs4423214 0.959 rs12800438 chr11:71171003 G/A cg05163923 chr11:71159392 DHCR7 0.87 13.22 0.58 1.58e-32 Vitamin D levels; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs898097 0.756 rs56249965 chr17:80806603 C/G cg15369054 chr17:80825471 TBCD 0.41 5.76 0.3 1.85e-8 Breast cancer; LIHC cis rs748404 0.697 rs513970 chr15:43579566 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.47 8.04 0.4 1.52e-14 Lung cancer; LIHC cis rs7412746 0.658 rs12090215 chr1:150893660 C/A cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs739401 0.611 rs2239899 chr11:3024624 A/G cg08508325 chr11:3079039 CARS 0.31 6.74 0.34 6.56e-11 Longevity; LIHC cis rs17376456 0.877 rs12153501 chr5:93360866 T/G cg25358565 chr5:93447407 FAM172A 1.1 10.04 0.48 5.77e-21 Diabetic retinopathy; LIHC cis rs2075371 0.611 rs1862045 chr7:134023412 A/G cg20476274 chr7:133979776 SLC35B4 0.48 6.35 0.32 6.72e-10 Mean platelet volume; LIHC cis rs7267979 1.000 rs12428 chr20:25433821 G/T cg24626310 chr20:25276739 ABHD12;PYGB -0.41 -6.2 -0.32 1.62e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.31 0.41 2.25e-15 Height; LIHC cis rs950169 0.922 rs11630760 chr15:85113337 G/T cg12863693 chr15:85201151 NMB 0.45 6.2 0.32 1.65e-9 Schizophrenia; LIHC cis rs684232 0.666 rs423887 chr17:593600 A/G cg15660573 chr17:549704 VPS53 -0.7 -9.65 -0.46 1.21e-19 Prostate cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg24043861 chr14:73396628 DCAF4 0.44 6.51 0.33 2.71e-10 Hepatitis; LIHC trans rs11098499 0.779 rs10016060 chr4:120298412 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs708547 0.624 rs1277284 chr4:57855361 T/G cg25525207 chr4:57843836 C4orf14;POLR2B -0.43 -6.73 -0.34 7.01e-11 Response to bleomycin (chromatid breaks); LIHC cis rs910316 0.934 rs7141705 chr14:75655352 G/C cg11812906 chr14:75593930 NEK9 -0.66 -12.35 -0.56 3.03e-29 Height; LIHC cis rs10792665 0.640 rs10751082 chr11:82625273 G/A cg24227371 chr11:82718527 RAB30 -0.27 -6.25 -0.32 1.26e-9 Obesity-related traits; LIHC trans rs2749592 0.550 rs7917262 chr10:37874602 A/C cg27523141 chr10:43048294 ZNF37B -0.37 -6.3 -0.32 8.92e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs5753618 0.561 rs2040533 chr22:31679110 G/C cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs2304069 0.545 rs13168011 chr5:149392377 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.6 8.49 0.42 6.46e-16 HIV-1 control; LIHC cis rs360798 0.532 rs1022110 chr2:63046039 T/G cg17519650 chr2:63277830 OTX1 -0.47 -7.26 -0.37 2.56e-12 Coronary artery disease; LIHC trans rs60843830 1.000 rs3791220 chr2:227066 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.64 9.14 0.44 5.85e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2717559 0.561 rs7841267 chr8:143881683 A/C cg06565975 chr8:143823917 SLURP1 -0.39 -6.38 -0.33 5.59e-10 Urinary tract infection frequency; LIHC cis rs897984 0.568 rs72799330 chr16:30893555 C/A cg02466173 chr16:30829666 NA -0.42 -6.16 -0.32 2.04e-9 Dementia with Lewy bodies; LIHC cis rs17685 0.753 rs13240404 chr7:75675719 C/T cg16684958 chr7:75615977 POR -0.51 -8.48 -0.42 6.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23967809 chr8:141647658 NA 0.47 6.85 0.35 3.38e-11 Pancreatic cancer; LIHC cis rs9611565 0.649 rs139540 chr22:42178040 C/T cg03806693 chr22:41940476 POLR3H -0.79 -9.02 -0.44 1.34e-17 Vitiligo; LIHC cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg03517284 chr6:25882590 NA 0.88 12.38 0.56 2.37e-29 Blood metabolite levels; LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg25811766 chr13:21894605 NA 0.82 14.82 0.63 1.03e-38 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs1799949 0.931 rs9912203 chr17:41445145 A/G cg25072359 chr17:41440525 NA -0.39 -6.11 -0.31 2.65e-9 Menopause (age at onset); LIHC cis rs4934494 0.911 rs7098233 chr10:91422868 A/C cg19698084 chr10:91461284 KIF20B 0.45 6.26 0.32 1.16e-9 Red blood cell count; LIHC cis rs4853036 0.951 rs3755391 chr2:70141519 C/T cg02498382 chr2:70120550 SNRNP27 -0.4 -6.28 -0.32 1.05e-9 Colorectal or endometrial cancer; LIHC cis rs3806843 0.735 rs6849 chr5:140086191 G/T cg16179182 chr5:140090404 VTRNA1-1 0.36 5.9 0.3 8.66e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12640387 chr1:6694331 THAP3;DNAJC11 -0.42 -6.14 -0.32 2.26e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 1.000 rs785486 chr1:46575148 G/C cg03146154 chr1:46216737 IPP -0.45 -7.22 -0.36 3.36e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs600806 0.850 rs6537757 chr1:109936682 G/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.17 -0.36 4.54e-12 Intelligence (multi-trait analysis); LIHC cis rs11628318 0.614 rs62007925 chr14:103128288 G/A cg12046867 chr14:103022105 NA 0.5 7.24 0.36 3.01e-12 Platelet count; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.41 0.61 3.94e-37 Prudent dietary pattern; LIHC trans rs1552244 0.572 rs6783705 chr3:10164783 A/G cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs57221529 0.709 rs111352378 chr5:577079 G/A cg09021430 chr5:549028 NA -0.45 -9.08 -0.44 9.1e-18 Lung disease severity in cystic fibrosis; LIHC cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg11644478 chr21:40555479 PSMG1 0.83 10.86 0.51 8.58e-24 Cognitive function; LIHC cis rs6500602 0.964 rs2896893 chr16:4478559 T/A cg08645402 chr16:4508243 NA 0.39 7.36 0.37 1.41e-12 Schizophrenia; LIHC cis rs908922 0.676 rs1337338 chr1:152511885 G/A cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC cis rs360798 0.512 rs2710640 chr2:63144305 A/G cg17519650 chr2:63277830 OTX1 0.56 8.5 0.42 6.1e-16 Coronary artery disease; LIHC cis rs2637266 0.905 rs3923669 chr10:78375047 T/C cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC trans rs11165623 0.585 rs6698447 chr1:96999473 C/T cg10631902 chr5:14652156 NA -0.29 -6.81 -0.35 4.31e-11 Hip circumference;Waist circumference; LIHC cis rs7487075 0.619 rs4768718 chr12:46834336 G/C cg23829395 chr12:46796953 NA 0.35 6.19 0.32 1.76e-9 Itch intensity from mosquito bite; LIHC cis rs7165170 0.678 rs2010673 chr15:91201285 C/T cg26821196 chr15:91095069 CRTC3 -0.37 -6.84 -0.35 3.66e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7927592 0.913 rs12363722 chr11:68236291 A/C cg01657329 chr11:68192670 LRP5 -0.46 -5.91 -0.3 8.17e-9 Total body bone mineral density; LIHC cis rs2370759 1.000 rs79806114 chr10:32618022 T/C cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs2795502 1.000 rs2473119 chr10:43339038 A/T cg27426351 chr10:43362370 NA -0.46 -5.8 -0.3 1.5e-8 Blood protein levels; LIHC cis rs8141529 0.664 rs5762861 chr22:29250505 T/G cg02153584 chr22:29168773 CCDC117 0.41 6.16 0.32 2e-9 Lymphocyte counts; LIHC cis rs4919694 1.000 rs112809537 chr10:104670346 C/T cg04362960 chr10:104952993 NT5C2 1.13 8.8 0.43 6.86e-17 Arsenic metabolism; LIHC cis rs1862618 0.671 rs2034244 chr5:56242774 T/C cg24531977 chr5:56204891 C5orf35 0.51 7.3 0.37 2.04e-12 Initial pursuit acceleration; LIHC cis rs7927771 1.000 rs7105282 chr11:47805614 C/A cg20135002 chr11:47629003 NA -0.55 -9.27 -0.45 2.17e-18 Subjective well-being; LIHC cis rs943466 1.000 rs73412140 chr6:33757014 G/T cg25922239 chr6:33757077 LEMD2 -0.47 -5.78 -0.3 1.66e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs2354432 1.000 rs2354432 chr1:146693229 C/T cg25205988 chr1:146714368 CHD1L 0.94 13.32 0.58 6.65e-33 Mitochondrial DNA levels; LIHC cis rs7539624 0.541 rs4653499 chr1:223892703 T/C cg07395969 chr1:223900822 CAPN2 0.53 6.01 0.31 4.8e-9 Schizophrenia; LIHC cis rs8056893 0.775 rs6499172 chr16:68376570 A/G cg02226672 chr16:68398533 SMPD3 0.47 6.73 0.34 7.05e-11 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs10128251 0.962 rs4748018 chr10:5711507 T/A cg24097872 chr10:5724021 NA 0.79 11.37 0.52 1.24e-25 Childhood ear infection; LIHC cis rs2573652 0.723 rs4577068 chr15:100515959 T/A cg09918751 chr15:100517450 ADAMTS17 -0.91 -16.71 -0.67 3.03e-46 Height; LIHC cis rs1348850 0.645 rs10181259 chr2:178428256 C/A cg27490568 chr2:178487706 NA 0.75 9.26 0.45 2.26e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9916302 0.904 rs8065879 chr17:37515978 G/A cg03013999 chr17:37608204 MED1 -0.36 -5.99 -0.31 5.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs3741404 0.791 rs7112960 chr11:63907079 A/G cg24431193 chr11:63883947 FLRT1;MACROD1 -0.38 -5.95 -0.31 6.72e-9 Platelet count; LIHC cis rs7703744 0.747 rs6896277 chr5:118678721 C/T cg04195774 chr5:118677172 TNFAIP8 -0.4 -5.72 -0.3 2.27e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs477692 0.905 rs563859 chr10:131417586 T/C cg19680672 chr10:131412579 MGMT -0.43 -6.62 -0.34 1.43e-10 Response to temozolomide; LIHC cis rs4450131 0.569 rs3824801 chr10:126356840 T/G cg20435097 chr10:126320824 FAM53B 0.59 10.73 0.5 2.43e-23 White blood cell count (basophil); LIHC cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -10.41 -0.49 3.04e-22 Platelet count; LIHC cis rs11677370 0.561 rs10084170 chr2:3820204 G/C cg17052675 chr2:3827356 NA -0.57 -7.59 -0.38 3.13e-13 Type 2 diabetes; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg21666675 chr3:14165843 TMEM43;CHCHD4 -0.43 -6.35 -0.32 6.91e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs60871478 1.000 rs62432253 chr7:802928 A/G cg04347379 chr7:794485 HEATR2 -0.4 -5.78 -0.3 1.66e-8 Cerebrospinal P-tau181p levels; LIHC cis rs9596863 0.950 rs9563183 chr13:54396931 A/C ch.13.53330881F chr13:54432880 NA 0.45 6.1 0.31 2.82e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1577917 1.000 rs12203493 chr6:86758642 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.31 -0.37 1.84e-12 Response to antipsychotic treatment; LIHC cis rs4906332 1.000 rs1951389 chr14:103898525 G/C cg19000871 chr14:103996768 TRMT61A -0.46 -7.9 -0.39 3.81e-14 Coronary artery disease; LIHC cis rs1552244 0.882 rs56224841 chr3:10044014 A/C cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs17376456 0.877 rs10060160 chr5:93387879 G/A cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs2354432 0.556 rs2883319 chr1:146838177 A/G cg25205988 chr1:146714368 CHD1L -0.84 -9.48 -0.46 4.43e-19 Mitochondrial DNA levels; LIHC cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg20887711 chr4:1340912 KIAA1530 0.45 6.01 0.31 4.77e-9 Obesity-related traits; LIHC cis rs11583043 1.000 rs3861734 chr1:101489461 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.86 0.43 4.4e-17 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2075371 1.000 rs2598294 chr7:133991690 C/T cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC cis rs10256972 0.669 rs10229964 chr7:1051776 A/G cg16145915 chr7:1198662 ZFAND2A -0.26 -6.11 -0.31 2.66e-9 Longevity;Endometriosis; LIHC cis rs72653721 0.627 rs57786993 chr6:11070940 T/A cg13562911 chr6:11044106 ELOVL2 0.5 7.26 0.37 2.7e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs12474201 0.832 rs4953419 chr2:46989869 T/G cg06386533 chr2:46925753 SOCS5 0.61 6.98 0.35 1.56e-11 Height; LIHC cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.06e-10 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18455759 chr8:126443767 TRIB1 0.44 6.29 0.32 9.77e-10 Cognitive function; LIHC cis rs61677309 0.638 rs4938493 chr11:118144804 T/G cg06090739 chr11:118230722 UBE4A 0.32 6.03 0.31 4.34e-9 Lung cancer in ever smokers; LIHC cis rs10504073 0.669 rs55948643 chr8:50026403 C/G cg00325661 chr8:49890786 NA 0.32 7.19 0.36 4.09e-12 Blood metabolite ratios; LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg26338869 chr17:61819248 STRADA 0.6 8.75 0.43 9.91e-17 Prudent dietary pattern; LIHC cis rs7937682 0.855 rs527078 chr11:111479713 T/C cg09085632 chr11:111637200 PPP2R1B -0.89 -10.78 -0.5 1.6e-23 Primary sclerosing cholangitis; LIHC cis rs3806843 1.000 rs6885319 chr5:140200611 A/C cg19875535 chr5:140030758 IK 0.36 5.82 0.3 1.36e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2479724 0.935 rs2025951 chr6:41827193 C/T cg17623882 chr6:41773611 USP49 0.56 8.98 0.44 1.84e-17 Menarche (age at onset); LIHC trans rs7246657 0.882 rs8112610 chr19:37928730 C/A cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg22867288 chr6:57086716 RAB23 -0.41 -6.05 -0.31 3.8e-9 Triglycerides; LIHC cis rs1816752 0.819 rs7400583 chr13:24990054 C/T cg22771759 chr13:24902376 NA 0.3 5.87 0.3 1.02e-8 Obesity-related traits; LIHC cis rs6726292 0.539 rs2580769 chr2:55214618 A/C cg09592903 chr2:55203963 RTN4 0.43 6.83 0.35 3.86e-11 Obesity (extreme); LIHC cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg27286337 chr10:134555280 INPP5A 0.9 12.42 0.56 1.75e-29 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7412746 0.503 rs72704639 chr1:150798335 A/C cg17724175 chr1:150552817 MCL1 0.45 8.97 0.44 1.97e-17 Melanoma; LIHC trans rs1005277 0.579 rs1780138 chr10:38501654 A/G cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg11764359 chr7:65958608 NA -0.69 -9.39 -0.45 8.46e-19 Aortic root size; LIHC cis rs3096299 0.685 rs4785568 chr16:89553707 A/G cg02244288 chr16:89573955 SPG7 -0.3 -5.77 -0.3 1.74e-8 Multiple myeloma (IgH translocation); LIHC cis rs7945718 0.905 rs7935997 chr11:12728651 A/G cg25843174 chr11:12811716 TEAD1 0.35 7.84 0.39 5.8e-14 Educational attainment (years of education); LIHC cis rs7250872 0.619 rs2396359 chr19:1819125 T/C cg18850929 chr19:1828978 REXO1 0.39 6.36 0.33 6.4e-10 Bipolar disorder; LIHC cis rs67311347 0.577 rs2371129 chr3:40248393 C/T cg18306943 chr3:40428807 ENTPD3 -0.39 -6.54 -0.33 2.21e-10 Renal cell carcinoma; LIHC cis rs6570726 0.846 rs6899900 chr6:145883873 T/G cg05347473 chr6:146136440 FBXO30 0.36 5.88 0.3 9.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg23758822 chr17:41437982 NA 0.94 17.89 0.7 5.39e-51 Menopause (age at onset); LIHC cis rs919433 0.783 rs2565155 chr2:198236425 A/G cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.8e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2153535 0.580 rs6902001 chr6:8477055 T/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00435469 chr11:1495117 HCCA2 0.43 6.08 0.31 3.24e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs8014204 0.935 rs1799900 chr14:75367740 G/A cg08847533 chr14:75593920 NEK9 -0.38 -6.4 -0.33 5.15e-10 Caffeine consumption; LIHC trans rs13381277 0.850 rs9951590 chr18:74330117 T/C cg17352830 chr21:37617589 DOPEY2 -0.55 -6.4 -0.33 5e-10 Dental caries; LIHC cis rs6565189 0.865 rs4350585 chr16:30505513 A/G cg17640201 chr16:30407289 ZNF48 0.51 6.03 0.31 4.29e-9 Tonsillectomy; LIHC cis rs7238033 0.624 rs4479340 chr18:43308955 C/T cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs9527 0.518 rs10883802 chr10:104680362 C/T cg15744005 chr10:104629667 AS3MT 0.42 5.87 0.3 1.04e-8 Arsenic metabolism; LIHC cis rs6430585 0.640 rs3816155 chr2:136552526 A/C cg07169764 chr2:136633963 MCM6 -1.11 -16.35 -0.66 8.02e-45 Corneal structure; LIHC cis rs12493885 0.769 rs57354204 chr3:153755718 C/T cg10247383 chr3:153839028 SGEF 0.61 5.8 0.3 1.53e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs6762 0.748 rs28735718 chr11:839629 A/G cg15787769 chr11:842744 TSPAN4;POLR2L -0.62 -7.55 -0.38 3.97e-13 Mean platelet volume; LIHC trans rs800082 0.799 rs9870285 chr3:144236432 C/A cg24215973 chr2:240111563 HDAC4 0.44 6.36 0.33 6.4e-10 Smoking behavior; LIHC cis rs3892630 0.878 rs2903759 chr19:33195947 A/G cg22980127 chr19:33182716 NUDT19 1.02 12.3 0.55 4.95e-29 Red blood cell traits; LIHC cis rs801193 1.000 rs2286684 chr7:66129830 G/T cg18876405 chr7:65276391 NA -0.43 -7.37 -0.37 1.31e-12 Aortic root size; LIHC cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg22963979 chr7:1858916 MAD1L1 -0.37 -6.0 -0.31 5.05e-9 Bipolar disorder and schizophrenia; LIHC cis rs7927592 0.913 rs4988291 chr11:68381607 G/A cg20283391 chr11:68216788 NA -0.52 -7.7 -0.38 1.43e-13 Total body bone mineral density; LIHC cis rs9910055 0.530 rs2269905 chr17:42294462 A/G cg13607699 chr17:42295918 UBTF 0.65 11.63 0.53 1.48e-26 Total body bone mineral density; LIHC cis rs17685 0.671 rs60303271 chr7:75760008 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9581857 0.579 rs3759433 chr13:27997999 C/T cg01674679 chr13:27998804 GTF3A -0.46 -6.69 -0.34 9e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg12311346 chr5:56204834 C5orf35 -0.56 -7.35 -0.37 1.45e-12 Initial pursuit acceleration; LIHC cis rs10197940 0.624 rs6731486 chr2:152410732 C/T cg19508488 chr2:152266495 RIF1 -0.59 -8.81 -0.43 6.57e-17 Lung cancer; LIHC cis rs9614461 0.702 rs3788648 chr22:45727180 G/A cg13318129 chr22:45737514 FAM118A 0.53 7.65 0.38 2.03e-13 Tonsillectomy; LIHC cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg07424592 chr7:64974309 NA 0.74 8.56 0.42 3.98e-16 Diabetic kidney disease; LIHC cis rs17001868 0.568 rs2294350 chr22:40784278 C/T cg07138101 chr22:40742427 ADSL 0.55 6.4 0.33 5.12e-10 Mammographic density (dense area); LIHC cis rs9814567 0.806 rs2888670 chr3:134326684 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.37 -0.45 9.84e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg05484376 chr2:27715224 FNDC4 0.36 6.16 0.32 2.07e-9 Total body bone mineral density; LIHC cis rs7959452 0.640 rs4761154 chr12:69705362 A/G cg14784868 chr12:69753453 YEATS4 -0.88 -16.79 -0.67 1.44e-46 Blood protein levels; LIHC cis rs5769765 0.862 rs9616392 chr22:50314705 G/A cg09182678 chr22:50328711 NA -0.46 -6.68 -0.34 9.66e-11 Schizophrenia; LIHC cis rs17125944 0.686 rs4450307 chr14:53334783 G/A cg00686598 chr14:53173677 PSMC6 -0.82 -9.18 -0.44 4.08e-18 Alzheimer's disease (late onset); LIHC cis rs4253772 0.638 rs6007845 chr22:46718417 A/T cg09491104 chr22:46646882 C22orf40 0.64 7.04 0.36 1.06e-11 LDL cholesterol;Cholesterol, total; LIHC trans rs875971 0.545 rs4718364 chr7:66001340 C/A cg26939375 chr7:64535504 NA 0.4 6.31 0.32 8.63e-10 Aortic root size; LIHC cis rs875971 0.928 rs2036263 chr7:65800197 C/T cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs477692 0.699 rs471390 chr10:131382825 A/G cg19680672 chr10:131412579 MGMT 0.39 5.83 0.3 1.28e-8 Response to temozolomide; LIHC cis rs67981189 0.593 rs8020480 chr14:71528044 C/A cg15816911 chr14:71606274 NA 0.42 6.82 0.35 4.07e-11 Schizophrenia; LIHC cis rs1670533 1.000 rs11247971 chr4:1053580 A/G cg27284194 chr4:1044797 NA 0.6 8.94 0.44 2.5e-17 Recombination rate (females); LIHC cis rs12477438 0.798 rs7606635 chr2:99644782 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.67 -0.38 1.86e-13 Chronic sinus infection; LIHC cis rs6546550 0.835 rs13002091 chr2:70118388 C/T cg02498382 chr2:70120550 SNRNP27 -0.44 -7.48 -0.37 6.38e-13 Prevalent atrial fibrillation; LIHC cis rs6540556 0.517 rs11119328 chr1:209885318 C/A cg05527609 chr1:210001259 C1orf107 -0.58 -7.65 -0.38 2.01e-13 Red blood cell count; LIHC cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg03264133 chr6:25882463 NA 0.87 11.56 0.53 2.65e-26 Blood metabolite levels; LIHC cis rs9372498 0.505 rs1690657 chr6:118650470 C/A cg01339444 chr6:118972232 C6orf204 0.71 6.25 0.32 1.22e-9 Diastolic blood pressure; LIHC cis rs546131 0.642 rs10501136 chr11:34846516 A/G cg11058730 chr11:34937778 PDHX;APIP 0.52 6.42 0.33 4.46e-10 Lung disease severity in cystic fibrosis; LIHC cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg02353165 chr6:42928485 GNMT -0.81 -12.6 -0.56 3.68e-30 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs10411161 1.000 rs3764540 chr19:52380681 T/A cg22319618 chr22:45562946 NUP50 -0.55 -7.42 -0.37 9.4e-13 Breast cancer; LIHC cis rs2816062 0.786 rs2816055 chr1:18898248 A/G cg18795169 chr1:18902165 NA -0.8 -18.16 -0.7 4.62e-52 Urate levels in lean individuals; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg14197205 chr17:28256862 EFCAB5;SSH2 0.4 6.2 0.32 1.6e-9 Calcium levels; LIHC cis rs9322817 0.583 rs7746856 chr6:105146360 A/C cg02098413 chr6:105308735 HACE1 0.37 6.54 0.33 2.24e-10 Thyroid stimulating hormone; LIHC cis rs4819052 0.788 rs9978857 chr21:46705155 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.66 9.45 0.46 5.48e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11997175 0.603 rs4739381 chr8:33806892 C/A ch.8.33884649F chr8:33765107 NA 0.37 6.23 0.32 1.41e-9 Body mass index; LIHC cis rs8062405 0.755 rs4788074 chr16:28593597 A/G cg07382826 chr16:28625726 SULT1A1 -0.49 -7.73 -0.39 1.23e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2573652 0.722 rs11858932 chr15:100542763 G/A cg09918751 chr15:100517450 ADAMTS17 -0.7 -12.16 -0.55 1.61e-28 Height; LIHC cis rs6089584 1.000 rs6089585 chr20:60564395 G/A cg06108461 chr20:60628389 TAF4 -0.88 -13.71 -0.6 2.16e-34 Body mass index; LIHC cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg03517284 chr6:25882590 NA -0.42 -6.51 -0.33 2.7e-10 Height; LIHC trans rs60752752 0.852 rs57572338 chr1:153370725 G/T cg14901121 chr8:98817630 LAPTM4B -0.43 -7.01 -0.35 1.27e-11 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs5769707 0.837 rs1573726 chr22:50032872 G/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.37 -0.41 1.48e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9467773 0.526 rs9688946 chr6:26367445 C/A cg09904177 chr6:26538194 HMGN4 -0.37 -5.79 -0.3 1.57e-8 Intelligence (multi-trait analysis); LIHC cis rs7660520 0.524 rs6839881 chr4:183729137 A/T cg04181038 chr4:183730758 NA 0.41 6.19 0.32 1.75e-9 Pediatric autoimmune diseases; LIHC cis rs1865760 1.000 rs3830057 chr6:25918510 G/T cg17691542 chr6:26056736 HIST1H1C 0.42 6.27 0.32 1.1e-9 Height; LIHC cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg11890956 chr21:40555474 PSMG1 1.03 14.83 0.63 8.98e-39 Cognitive function; LIHC cis rs2408955 0.522 rs11168408 chr12:48498327 G/A cg21466736 chr12:48725269 NA 0.64 9.17 0.44 4.67e-18 Glycated hemoglobin levels; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs1008375 1.000 rs2159584 chr4:17620568 G/A cg16339924 chr4:17578868 LAP3 0.44 6.13 0.31 2.42e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs422249 0.547 rs174536 chr11:61551927 A/C cg27386326 chr11:61587980 NA 0.7 14.63 0.62 5.66e-38 Trans fatty acid levels; LIHC cis rs2760061 0.784 rs708116 chr1:228198196 C/A cg02753203 chr1:228287806 NA 0.48 7.97 0.4 2.42e-14 Diastolic blood pressure; LIHC cis rs12365397 0.775 rs2132484 chr11:43244386 A/C cg16667275 chr11:43333495 API5 0.41 6.13 0.31 2.36e-9 Migraine; LIHC cis rs1555322 0.530 rs2425047 chr20:33871675 G/T cg17927777 chr20:33865990 NA -0.54 -6.53 -0.33 2.45e-10 Attention deficit hyperactivity disorder; LIHC cis rs9814567 1.000 rs7619451 chr3:134233238 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -11.28 -0.52 2.63e-25 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg02782426 chr3:40428986 ENTPD3 0.34 6.18 0.32 1.77e-9 Renal cell carcinoma; LIHC cis rs7772486 0.754 rs4566902 chr6:146244128 A/G cg23711669 chr6:146136114 FBXO30 -0.64 -11.11 -0.51 1.08e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg05896524 chr21:47604654 C21orf56 -0.51 -8.14 -0.4 7.6e-15 Testicular germ cell tumor; LIHC cis rs870825 0.929 rs10003354 chr4:185589782 G/A cg04058563 chr4:185651563 MLF1IP 0.76 6.24 0.32 1.28e-9 Blood protein levels; LIHC cis rs78456975 1.000 rs111935361 chr2:1554192 C/A cg01028140 chr2:1542097 TPO -0.56 -6.64 -0.34 1.27e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2933343 1.000 rs2933343 chr3:128658492 G/A cg25356066 chr3:128598488 ACAD9 0.53 7.13 0.36 5.89e-12 IgG glycosylation; LIHC trans rs11098499 0.754 rs28643450 chr4:120245242 G/A cg25214090 chr10:38739885 LOC399744 0.52 8.36 0.41 1.57e-15 Corneal astigmatism; LIHC cis rs4820539 0.934 rs3788348 chr22:23467946 G/C cg14186256 chr22:23484241 RTDR1 0.98 21.26 0.75 1.65e-64 Bone mineral density; LIHC cis rs2153535 0.563 rs3117071 chr6:8537908 C/T cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.62e-15 Motion sickness; LIHC cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.54 0.38 4.23e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2197308 0.667 rs11181073 chr12:37898543 A/G cg26384229 chr12:38710491 ALG10B 0.81 10.43 0.49 2.66e-22 Morning vs. evening chronotype; LIHC cis rs708547 0.836 rs1713997 chr4:57843863 G/C cg25525207 chr4:57843836 C4orf14;POLR2B -0.46 -6.86 -0.35 3.2e-11 Response to bleomycin (chromatid breaks); LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.17 -0.32 1.91e-9 Total body bone mineral density; LIHC cis rs9814567 0.964 rs6772406 chr3:134210183 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.51 -0.56 8.09e-30 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7103648 0.695 rs12223593 chr11:47789082 T/G cg20307385 chr11:47447363 PSMC3 0.98 15.78 0.65 1.63e-42 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs1801251 1.000 rs1801251 chr2:233633460 G/A cg08000102 chr2:233561755 GIGYF2 0.76 11.5 0.53 4.2e-26 Coronary artery disease; LIHC cis rs868036 0.681 rs4776981 chr15:68109474 G/A cg24579218 chr15:68104479 NA -0.35 -5.91 -0.3 8.1e-9 Restless legs syndrome; LIHC cis rs4555082 0.834 rs2816624 chr14:105733909 A/G cg06808227 chr14:105710500 BRF1 -0.55 -7.17 -0.36 4.66e-12 Mean platelet volume;Platelet distribution width; LIHC trans rs3942852 0.568 rs10769313 chr11:48097466 A/G cg03929089 chr4:120376271 NA -0.46 -6.06 -0.31 3.57e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs2153535 0.580 rs1414349 chr6:8472290 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs2075165 1.000 rs2075165 chr1:156215899 G/A cg10096929 chr1:156261403 TMEM79 0.38 6.12 0.31 2.51e-9 Tonsillectomy; LIHC cis rs4975709 0.569 rs931509 chr5:1858821 A/T cg15595755 chr5:1867978 NA 0.41 7.96 0.4 2.57e-14 Cardiovascular disease risk factors; LIHC cis rs7264396 0.690 rs2425165 chr20:34438059 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.83 -0.51 1.07e-23 Total cholesterol levels; LIHC cis rs1878931 0.517 rs17685105 chr16:3413749 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.71 -11.1 -0.51 1.19e-24 Body mass index (adult); LIHC cis rs9318086 0.712 rs9510916 chr13:24442789 C/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.58 11.46 0.53 5.97e-26 Myopia (pathological); LIHC cis rs6963495 0.818 rs117028299 chr7:105162310 T/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs7116495 0.609 rs73543612 chr11:71820350 C/T cg26138937 chr11:71823887 C11orf51 1.34 10.79 0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC cis rs34779708 0.966 rs4294520 chr10:35422506 C/T cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12220238 1.000 rs10824099 chr10:75943625 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.7 6.68 0.34 9.76e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg26831259 chr4:1366826 KIAA1530 0.35 5.75 0.3 1.99e-8 Obesity-related traits; LIHC cis rs6964587 1.000 rs17164263 chr7:91581566 T/A cg17063962 chr7:91808500 NA -1.02 -19.48 -0.73 2.17e-57 Breast cancer; LIHC cis rs8114671 0.545 rs2378335 chr20:33756830 A/C cg08999081 chr20:33150536 PIGU 0.41 5.78 0.3 1.72e-8 Height; LIHC cis rs35110281 0.837 rs2838340 chr21:45076373 A/G cg04455712 chr21:45112962 RRP1B 0.41 7.28 0.37 2.37e-12 Mean corpuscular volume; LIHC cis rs9814567 1.000 rs9289475 chr3:134236459 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg11941060 chr3:133502564 NA 0.4 6.09 0.31 3.05e-9 Iron status biomarkers; LIHC trans rs12620999 1.000 rs4377286 chr2:238069686 C/T cg15676719 chr1:167598521 RCSD1 -0.39 -6.95 -0.35 1.84e-11 Systemic lupus erythematosus; LIHC cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.17 -0.36 4.62e-12 Bipolar disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25048202 chr15:66993412 SMAD6 0.44 6.63 0.34 1.3e-10 Lung function (FEV1/FVC); LIHC cis rs12887734 0.566 rs8548 chr14:104199580 A/C cg24130564 chr14:104152367 KLC1 -0.43 -6.98 -0.35 1.53e-11 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2303759 0.958 rs1465697 chr19:49837246 C/T cg22590775 chr19:49891494 CCDC155 0.47 7.55 0.38 3.93e-13 Multiple sclerosis; LIHC cis rs2425143 1.000 rs17093027 chr20:34319118 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg00990874 chr7:1149470 C7orf50 -0.7 -10.02 -0.48 7.11e-21 Bronchopulmonary dysplasia; LIHC cis rs7044106 0.762 rs1867254 chr9:123429078 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.35 0.52 1.51e-25 Hip circumference adjusted for BMI; LIHC cis rs9814567 0.762 rs13071253 chr3:134316653 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 7.39 0.37 1.13e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6089584 0.507 rs6061989 chr20:60627893 C/T cg23262073 chr20:60523788 NA -0.28 -5.78 -0.3 1.65e-8 Body mass index; LIHC cis rs9733 0.536 rs6661415 chr1:150635869 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs7412746 0.611 rs2256355 chr1:150811794 A/G cg17724175 chr1:150552817 MCL1 0.44 9.09 0.44 8.01e-18 Melanoma; LIHC cis rs1348850 0.513 rs6730406 chr2:178492722 C/T cg27490568 chr2:178487706 NA 0.72 9.78 0.47 4.54e-20 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12497850 0.931 rs9840684 chr3:48893780 T/C cg06212747 chr3:49208901 KLHDC8B 0.55 7.07 0.36 8.98e-12 Parkinson's disease; LIHC cis rs1707322 0.752 rs11211146 chr1:46109794 T/C cg03146154 chr1:46216737 IPP 0.57 9.64 0.46 1.32e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17685 0.753 rs4573217 chr7:75733946 G/A cg01364799 chr7:75623366 TMEM120A -0.5 -7.41 -0.37 9.97e-13 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9929218 1.000 rs9937664 chr16:68784603 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.39 -0.45 8.54e-19 Colorectal cancer; LIHC cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.38 0.45 9.22e-19 Bipolar disorder; LIHC cis rs4908768 0.906 rs55860300 chr1:8596335 G/A cg25722041 chr1:8623473 RERE 0.41 5.94 0.31 7.12e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg03136712 chr5:140053068 DND1 0.5 6.11 0.31 2.75e-9 Lung function (FEV1); LIHC cis rs6558174 0.965 rs6558172 chr8:22492052 C/T cg03733263 chr8:22462867 KIAA1967 0.39 5.77 0.3 1.76e-8 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06009330 chr2:70485380 PCYOX1 0.61 8.12 0.4 8.45e-15 Lung function (FEV1/FVC); LIHC cis rs7635838 0.785 rs7427412 chr3:11535020 G/A cg00170343 chr3:11313890 ATG7 0.4 6.19 0.32 1.67e-9 HDL cholesterol; LIHC cis rs8067354 0.645 rs2645491 chr17:57877049 C/T cg13753209 chr17:57696993 CLTC 0.72 11.38 0.52 1.15e-25 Hemoglobin concentration; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg16132339 chr22:24313637 DDTL;DDT -0.7 -13.58 -0.59 6.74e-34 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg24693881 chr1:107596107 NA -0.52 -9.38 -0.45 9.34e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg11890956 chr21:40555474 PSMG1 1.07 15.4 0.64 5.23e-41 Cognitive function; LIHC cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg18252515 chr7:66147081 NA -1.3 -16.95 -0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs2439831 0.850 rs28595038 chr15:44044859 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.47 0.42 7.46e-16 Lung cancer in ever smokers; LIHC cis rs9768139 0.696 rs4909177 chr7:158117047 A/T cg06219351 chr7:158114137 PTPRN2 -0.21 -5.88 -0.3 9.86e-9 Calcium levels; LIHC cis rs7666738 0.830 rs13133619 chr4:99067312 C/G cg05340658 chr4:99064831 C4orf37 -0.71 -13.0 -0.58 1.15e-31 Colonoscopy-negative controls vs population controls; LIHC trans rs2363709 1.000 rs6770280 chr3:67416712 T/C cg15775005 chr18:9136598 ANKRD12 -0.79 -6.05 -0.31 3.71e-9 IgE levels; LIHC cis rs5769765 1.000 rs2319458 chr22:50236306 G/A cg26441486 chr22:50317300 CRELD2 0.36 6.14 0.31 2.34e-9 Schizophrenia; LIHC cis rs9457247 1.000 rs1794693 chr6:167405670 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs7903847 0.642 rs7092350 chr10:99140218 A/T cg20016023 chr10:99160130 RRP12 -0.42 -6.68 -0.34 9.61e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs12497850 0.931 rs7621015 chr3:49016056 A/G cg07636037 chr3:49044803 WDR6 0.92 16.54 0.67 1.44e-45 Parkinson's disease; LIHC cis rs2029362 0.513 rs7931247 chr11:27746991 T/C cg18117895 chr11:27722066 BDNF -0.39 -5.76 -0.3 1.87e-8 Total body bone mineral density; LIHC cis rs3793683 0.928 rs10781585 chr10:134553369 C/A cg26818010 chr10:134567672 INPP5A 0.61 8.16 0.4 6.3e-15 Migraine; LIHC cis rs1144333 0.655 rs3765682 chr1:76333172 T/C cg03433033 chr1:76189801 ACADM 0.54 7.44 0.37 8.34e-13 Attention function in attention deficit hyperactive disorder; LIHC trans rs1814175 0.781 rs11040681 chr11:49981654 G/T cg18944383 chr4:111397179 ENPEP 0.27 7.06 0.36 9.34e-12 Height; LIHC cis rs12824058 0.831 rs4759653 chr12:130812604 T/C cg24229701 chr12:130821962 PIWIL1 0.44 6.81 0.35 4.49e-11 Menopause (age at onset); LIHC cis rs9818758 0.556 rs116432667 chr3:48947589 C/T cg07636037 chr3:49044803 WDR6 -0.79 -7.76 -0.39 9.98e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs4906332 1.000 rs17617307 chr14:103904965 C/G cg19000871 chr14:103996768 TRMT61A -0.45 -7.71 -0.38 1.37e-13 Coronary artery disease; LIHC cis rs4917833 0.510 rs754586 chr10:100224362 A/G cg19043522 chr10:100227446 HPSE2 0.4 5.96 0.31 6.35e-9 Pediatric bone mineral density (femoral neck); LIHC cis rs3015497 0.789 rs3015500 chr14:51108877 C/T cg09863266 chr14:51125203 SAV1 -0.42 -6.82 -0.35 4.2e-11 Mean platelet volume; LIHC cis rs1075232 1.000 rs56396205 chr15:31678385 G/A cg01030201 chr15:31746330 NA -0.79 -6.12 -0.31 2.56e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs9467773 0.869 rs9295689 chr6:26455811 T/C cg11502198 chr6:26597334 ABT1 0.44 6.4 0.33 5.18e-10 Intelligence (multi-trait analysis); LIHC cis rs968567 0.539 rs174556 chr11:61580635 C/T cg27386326 chr11:61587980 NA 0.69 14.45 0.62 2.72e-37 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs875971 0.862 rs2024192 chr7:66041447 G/T cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.22e-34 Aortic root size; LIHC cis rs2239547 0.563 rs6445547 chr3:52908577 T/C cg11645453 chr3:52864694 ITIH4 0.32 8.08 0.4 1.13e-14 Schizophrenia; LIHC cis rs9868809 0.772 rs9841602 chr3:48713570 A/G cg07636037 chr3:49044803 WDR6 -0.58 -6.95 -0.35 1.9e-11 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs4523957 0.855 rs11078883 chr17:2138828 C/G cg16513277 chr17:2031491 SMG6 -0.47 -7.63 -0.38 2.35e-13 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg11890956 chr21:40555474 PSMG1 -0.5 -8.17 -0.4 5.97e-15 Cognitive function; LIHC cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg26939375 chr7:64535504 NA 0.47 7.21 0.36 3.66e-12 Calcium levels; LIHC cis rs8078723 1.000 rs4795412 chr17:38150604 C/T cg17467752 chr17:38218738 THRA 0.73 13.22 0.58 1.65e-32 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg06238570 chr21:40685208 BRWD1 -0.48 -7.7 -0.38 1.5e-13 Cognitive function; LIHC trans rs11039798 1.000 rs10160423 chr11:48457227 G/T cg15704280 chr7:45808275 SEPT13 0.61 6.23 0.32 1.39e-9 Axial length; LIHC cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.99 0.7 2.16e-51 Gut microbiome composition (summer); LIHC cis rs600806 0.850 rs3879452 chr1:109929237 G/A cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08547432 chr19:50143419 RRAS 0.46 6.75 0.34 6.21e-11 Pancreatic cancer; LIHC cis rs9916302 0.707 rs11078903 chr17:37631924 G/A cg07936489 chr17:37558343 FBXL20 -0.84 -13.43 -0.59 2.61e-33 Glomerular filtration rate (creatinine); LIHC cis rs950169 0.887 rs71395453 chr15:85113490 G/C cg12863693 chr15:85201151 NMB 0.45 6.2 0.32 1.65e-9 Schizophrenia; LIHC cis rs1707322 1.000 rs1768818 chr1:46514286 G/C cg06784218 chr1:46089804 CCDC17 -0.36 -6.5 -0.33 2.8e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7223966 1.000 rs17549954 chr17:61707032 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.75 0.34 6.22e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6963495 0.818 rs56268110 chr7:105166712 T/C cg19920283 chr7:105172520 RINT1 0.7 6.58 0.34 1.76e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2708977 0.933 rs2464914 chr2:97179828 A/G cg01950434 chr2:97203154 ARID5A -0.52 -7.76 -0.39 9.74e-14 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs10193935 0.901 rs2088281 chr2:42672731 A/G cg27598129 chr2:42591480 NA 0.71 10.35 0.49 5.1e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs2806561 0.765 rs4333826 chr1:23517514 C/T cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.45e-11 Height; LIHC cis rs4665809 1.000 rs4665305 chr2:26313524 C/T cg27170947 chr2:26402098 FAM59B -0.62 -7.82 -0.39 6.74e-14 Gut microbiome composition (summer); LIHC trans rs6951245 0.580 rs78894484 chr7:1138721 T/G cg13565492 chr6:43139072 SRF -0.79 -7.32 -0.37 1.81e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7944735 0.508 rs4752871 chr11:47849432 C/G cg20307385 chr11:47447363 PSMC3 -0.51 -5.75 -0.3 1.97e-8 Intraocular pressure; LIHC cis rs2016586 0.522 rs66518367 chr22:36094486 G/T cg26342177 chr22:36113512 APOL5 -0.34 -5.74 -0.3 2.14e-8 Body mass index; LIHC cis rs1865760 0.566 rs2051544 chr6:26071093 C/T cg17691542 chr6:26056736 HIST1H1C 0.41 5.9 0.3 8.59e-9 Height; LIHC cis rs7584330 0.554 rs3751109 chr2:238427194 T/C cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs17685 0.784 rs1637043 chr7:75699099 G/A cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6076065 0.748 rs6076055 chr20:23333917 G/C cg11657817 chr20:23433608 CST11 0.31 6.74 0.34 6.71e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg22903471 chr2:27725779 GCKR -0.5 -8.62 -0.42 2.54e-16 Total body bone mineral density; LIHC cis rs8062405 0.789 rs1968752 chr16:28631585 G/T cg07382826 chr16:28625726 SULT1A1 0.47 7.21 0.36 3.6e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs66887589 0.616 rs10032299 chr4:120206419 C/T cg09307838 chr4:120376055 NA 0.53 7.8 0.39 7.47e-14 Diastolic blood pressure; LIHC cis rs7937682 0.924 rs1784782 chr11:111525764 A/C cg09085632 chr11:111637200 PPP2R1B -1.03 -12.38 -0.56 2.44e-29 Primary sclerosing cholangitis; LIHC trans rs13325613 0.915 rs34414382 chr3:46265190 C/T cg26337592 chr1:153642686 ILF2 0.68 6.2 0.32 1.66e-9 Monocyte count; LIHC cis rs7552404 0.727 rs6678348 chr1:76332463 C/T cg10523679 chr1:76189770 ACADM 0.57 7.17 0.36 4.75e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs597539 0.654 rs619727 chr11:68627535 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.72 10.23 0.48 1.3e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2279817 0.863 rs34430730 chr1:18015100 G/A cg21791023 chr1:18019539 ARHGEF10L -0.68 -8.05 -0.4 1.36e-14 Neuroticism; LIHC trans rs8002861 0.664 rs2325089 chr13:44450222 C/G cg17145862 chr1:211918768 LPGAT1 -0.49 -8.84 -0.43 5.04e-17 Leprosy; LIHC cis rs12701220 0.847 rs10272002 chr7:1047615 A/G cg04498913 chr7:1135747 C7orf50 0.38 5.84 0.3 1.18e-8 Bronchopulmonary dysplasia; LIHC cis rs6754311 0.731 rs2164210 chr2:136580287 T/C cg17750252 chr2:136567154 LCT 0.35 6.32 0.32 8.34e-10 Mosquito bite size; LIHC cis rs9814567 0.964 rs9841180 chr3:134191880 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -10.74 -0.5 2.14e-23 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs918629 0.798 rs2546199 chr5:95282091 A/C cg10483112 chr5:95245456 ELL2 -0.37 -6.46 -0.33 3.62e-10 IgG glycosylation; LIHC cis rs4755351 0.504 rs12418119 chr11:33347977 G/A cg05567920 chr11:33183001 CSTF3 0.4 5.75 0.3 1.97e-8 Lung cancer in ever smokers; LIHC cis rs9660992 0.626 rs1172113 chr1:205226288 T/C cg21545522 chr1:205238299 TMCC2 0.32 6.25 0.32 1.21e-9 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2651899 0.902 rs1736522 chr1:3080940 C/G cg22674798 chr1:3096360 PRDM16 0.25 6.34 0.32 7.07e-10 Migraine; LIHC trans rs7246657 0.943 rs6508711 chr19:37815134 G/T cg24637308 chr11:6592297 DNHD1 0.44 6.16 0.32 2.02e-9 Coronary artery calcification; LIHC cis rs11122272 0.735 rs2474631 chr1:231541341 T/A cg06096015 chr1:231504339 EGLN1 0.5 9.34 0.45 1.28e-18 Hemoglobin concentration; LIHC cis rs9914988 0.887 rs11656272 chr17:27091153 A/G cg20469991 chr17:27169893 C17orf63 -0.6 -7.04 -0.36 1.08e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs56104184 0.830 rs73061622 chr19:49358111 C/T cg21252483 chr19:49399788 TULP2 -0.69 -5.82 -0.3 1.35e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs4813802 0.724 rs2876052 chr20:6711572 C/T cg17608529 chr10:436626 DIP2C 0.53 6.09 0.31 3.1e-9 Colorectal cancer; LIHC cis rs477692 1.000 rs479478 chr10:131428959 G/A cg05714579 chr10:131428358 MGMT 0.46 7.58 0.38 3.38e-13 Response to temozolomide; LIHC cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg07424592 chr7:64974309 NA -0.8 -9.22 -0.45 3.22e-18 Diabetic kidney disease; LIHC cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg10360323 chr17:41437877 NA 0.4 5.92 0.31 7.69e-9 Menopause (age at onset); LIHC cis rs66573146 0.572 rs68169399 chr4:6952491 T/A cg00086871 chr4:6988644 TBC1D14 0.8 6.06 0.31 3.61e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.22 0.52 4.31e-25 Colorectal cancer; LIHC cis rs1008375 0.966 rs6813375 chr4:17649499 T/G cg02297831 chr4:17616191 MED28 0.5 7.8 0.39 7.38e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6088580 0.634 rs6059868 chr20:33079460 A/G cg08999081 chr20:33150536 PIGU 0.67 13.45 0.59 2.07e-33 Glomerular filtration rate (creatinine); LIHC cis rs57244997 0.582 rs73030432 chr6:162439864 G/A cg17173639 chr6:162384350 PARK2 -0.52 -6.68 -0.34 9.42e-11 Mosquito bite size; LIHC trans rs1814175 0.702 rs4881644 chr11:49786367 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.14 -0.78 5.71e-72 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17492891 chr22:41843204 TOB2 0.4 6.14 0.32 2.3e-9 Pancreatic cancer; LIHC cis rs7619427 1.000 rs7635417 chr3:44074449 C/T cg24966902 chr3:44043705 NA 0.5 7.08 0.36 8.07e-12 Schizophrenia; LIHC cis rs8017423 0.967 rs11627528 chr14:90719697 C/A cg14092571 chr14:90743983 NA 0.41 6.59 0.34 1.69e-10 Mortality in heart failure; LIHC cis rs10744422 1.000 rs2061101 chr12:123348925 C/A cg07706471 chr12:123319906 HIP1R -0.57 -6.96 -0.35 1.75e-11 Schizophrenia; LIHC trans rs208520 1.000 rs12189683 chr6:66977716 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.65 -7.18 -0.36 4.43e-12 Exhaled nitric oxide output; LIHC cis rs5769765 0.908 rs2319464 chr22:50265777 A/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs9790314 0.905 rs7613358 chr3:160949296 T/C cg03342759 chr3:160939853 NMD3 -0.76 -11.1 -0.51 1.21e-24 Morning vs. evening chronotype; LIHC cis rs1475911 0.708 rs11701371 chr21:43523972 C/G cg19766460 chr21:43528205 UMODL1;C21orf128 1.15 19.93 0.73 3.24e-59 IgG glycosylation; LIHC cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg02951883 chr7:2050386 MAD1L1 -0.55 -8.13 -0.4 7.85e-15 Bipolar disorder and schizophrenia; LIHC cis rs10791097 0.720 rs6590515 chr11:130733365 A/G cg09137382 chr11:130731461 NA -0.39 -5.85 -0.3 1.18e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9527 0.518 rs12771834 chr10:104655419 G/A cg15744005 chr10:104629667 AS3MT -0.44 -6.09 -0.31 3.01e-9 Arsenic metabolism; LIHC cis rs2836950 0.501 rs2836984 chr21:40700949 A/C cg11890956 chr21:40555474 PSMG1 -0.46 -7.5 -0.38 5.6e-13 Menarche (age at onset); LIHC cis rs62244186 0.659 rs6441844 chr3:44503579 C/T cg25364880 chr3:44379878 C3orf23 0.57 8.08 0.4 1.16e-14 Depressive symptoms; LIHC cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg26939375 chr7:64535504 NA 0.48 7.22 0.36 3.46e-12 Calcium levels; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg21548813 chr6:291882 DUSP22 -0.6 -8.52 -0.42 5.17e-16 Menopause (age at onset); LIHC cis rs1023500 0.596 rs133352 chr22:42434022 C/A cg00645731 chr22:42541494 CYP2D7P1 0.41 6.42 0.33 4.47e-10 Schizophrenia; LIHC cis rs2239547 0.562 rs35380116 chr3:52979178 A/G cg11645453 chr3:52864694 ITIH4 -0.23 -5.9 -0.3 8.8e-9 Schizophrenia; LIHC cis rs244731 0.920 rs244707 chr5:176555636 A/T cg17509989 chr5:176798049 RGS14 0.66 6.15 0.32 2.17e-9 Urate levels in lean individuals; LIHC cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg12463550 chr7:65579703 CRCP -0.65 -6.75 -0.34 6.26e-11 Diabetic kidney disease; LIHC cis rs17685 0.753 rs13240404 chr7:75675719 C/T cg04592579 chr7:75616294 TMEM120A -0.4 -6.83 -0.35 3.8e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2075371 1.000 rs1862047 chr7:133978078 G/C cg20476274 chr7:133979776 SLC35B4 0.76 13.09 0.58 5.08e-32 Mean platelet volume; LIHC cis rs7107174 1.000 rs11601161 chr11:78073280 A/G cg02023728 chr11:77925099 USP35 0.46 8.81 0.43 6.43e-17 Testicular germ cell tumor; LIHC cis rs9467773 0.626 rs6936006 chr6:26350565 A/G cg09904177 chr6:26538194 HMGN4 -0.37 -5.95 -0.31 6.82e-9 Intelligence (multi-trait analysis); LIHC cis rs28830936 0.966 rs11635067 chr15:42124673 G/C cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.98 -0.31 5.75e-9 Diastolic blood pressure; LIHC cis rs875971 1.000 rs3981131 chr7:65951677 A/G cg11764359 chr7:65958608 NA 0.9 16.05 0.66 1.33e-43 Aortic root size; LIHC cis rs6669384 0.774 rs12141901 chr1:208031234 G/A cg22525895 chr1:207977042 MIR29B2 -0.54 -5.91 -0.3 8.17e-9 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs2257205 0.667 rs73996262 chr17:56784426 C/T cg12560992 chr17:57184187 TRIM37 0.72 7.97 0.4 2.33e-14 Pancreatic cancer; LIHC cis rs34172651 0.517 rs11647120 chr16:24819806 A/G cg00339695 chr16:24857497 SLC5A11 0.73 10.57 0.5 9.04e-23 Intelligence (multi-trait analysis); LIHC cis rs1008375 0.902 rs6844984 chr4:17651304 C/G cg02297831 chr4:17616191 MED28 0.49 7.59 0.38 3.11e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4144743 0.759 rs67972765 chr17:45318326 G/A cg18085866 chr17:45331354 ITGB3 -0.64 -7.51 -0.38 5.05e-13 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23634318 chr6:46097671 ENPP4 0.43 6.5 0.33 2.91e-10 Lung function (FEV1/FVC); LIHC cis rs12188164 0.543 rs2672757 chr5:454732 A/G cg07599136 chr5:415885 AHRR 0.39 6.71 0.34 8.03e-11 Cystic fibrosis severity; LIHC cis rs7772486 0.754 rs702304 chr6:145990797 A/G cg13319975 chr6:146136371 FBXO30 0.37 6.05 0.31 3.74e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4843747 0.749 rs72818535 chr16:88074039 G/A cg06050784 chr16:88016603 BANP 0.39 6.64 0.34 1.2e-10 Menopause (age at onset); LIHC cis rs9470366 0.772 rs9918353 chr6:36622677 A/C cg08179530 chr6:36648295 CDKN1A 0.54 6.66 0.34 1.07e-10 QRS duration; LIHC cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg05368731 chr17:41323189 NBR1 0.72 12.32 0.55 4.18e-29 Menopause (age at onset); LIHC cis rs2559856 0.904 rs2695283 chr12:102089391 G/C cg12924262 chr12:102091054 CHPT1 0.53 8.62 0.42 2.44e-16 Blood protein levels; LIHC cis rs600806 0.854 rs11102974 chr1:109886371 G/A cg08911820 chr1:110026001 ATXN7L2 -0.57 -6.87 -0.35 3.13e-11 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.850 rs17226519 chr16:89839854 T/C cg19635926 chr16:89946313 TCF25 0.49 6.38 0.33 5.81e-10 Skin colour saturation; LIHC cis rs999943 0.846 rs999942 chr6:33624902 G/C cg14003231 chr6:33640908 ITPR3 0.39 7.78 0.39 8.43e-14 Obesity (extreme); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14564021 chr9:26892069 C9orf82 0.47 6.16 0.32 2.03e-9 Pancreatic cancer; LIHC cis rs11864453 0.514 rs2269918 chr16:72134831 C/A cg16558253 chr16:72132732 DHX38 -0.44 -7.29 -0.37 2.22e-12 Fibrinogen levels; LIHC cis rs7618501 0.815 rs3819325 chr3:49843723 T/C cg21467203 chr3:49911342 NA -0.41 -7.02 -0.36 1.17e-11 Intelligence (multi-trait analysis); LIHC cis rs311392 1.000 rs2671804 chr8:55088853 C/T cg11783602 chr8:55087084 NA -0.33 -6.49 -0.33 2.95e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs2991971 0.967 rs512026 chr1:46009946 G/T cg24296786 chr1:45957014 TESK2 0.53 7.99 0.4 2.15e-14 High light scatter reticulocyte count; LIHC cis rs270601 0.770 rs1007602 chr5:131602166 T/C cg24060327 chr5:131705240 SLC22A5 -0.53 -6.94 -0.35 1.96e-11 Acylcarnitine levels; LIHC cis rs7762018 0.769 rs74838157 chr6:170077323 G/A cg19338460 chr6:170058176 WDR27 -0.74 -8.42 -0.41 1.04e-15 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs4631830 0.657 rs2611502 chr10:51500301 A/G cg16070123 chr10:51489643 NA -0.38 -6.07 -0.31 3.36e-9 Prostate-specific antigen levels; LIHC cis rs526231 0.853 rs377192 chr5:102603554 C/T cg05225461 chr5:102596755 C5orf30 0.38 5.89 0.3 9.25e-9 Primary biliary cholangitis; LIHC cis rs679087 0.932 rs10843507 chr12:29931056 C/A cg14258853 chr12:29935411 TMTC1 0.48 7.99 0.4 2.14e-14 Schizophrenia; LIHC cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg05025164 chr4:1340916 KIAA1530 -0.41 -6.24 -0.32 1.32e-9 Obesity-related traits; LIHC cis rs7927592 0.763 rs10896327 chr11:68235275 G/C cg20283391 chr11:68216788 NA -0.38 -6.11 -0.31 2.73e-9 Total body bone mineral density; LIHC cis rs12824058 0.831 rs12829373 chr12:130814114 G/C cg24229701 chr12:130821962 PIWIL1 0.44 6.77 0.34 5.55e-11 Menopause (age at onset); LIHC cis rs4862750 0.914 rs1991255 chr4:187875340 G/A cg11301795 chr4:187892539 NA -0.26 -6.78 -0.34 5.43e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg05590025 chr7:65112418 INTS4L2 -0.65 -7.25 -0.36 2.89e-12 Diabetic kidney disease; LIHC cis rs7927592 0.913 rs7104345 chr11:68316772 G/A cg16797656 chr11:68205561 LRP5 0.51 8.04 0.4 1.47e-14 Total body bone mineral density; LIHC cis rs887797 0.557 rs8072699 chr17:64592569 T/C cg27019712 chr17:64599478 PRKCA -0.4 -6.86 -0.35 3.22e-11 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC cis rs847649 0.842 rs7789252 chr7:102624227 C/A cg18108683 chr7:102477205 FBXL13 -0.46 -7.15 -0.36 5.27e-12 Morning vs. evening chronotype; LIHC cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg09025071 chr16:1593152 IFT140;TMEM204 0.32 6.37 0.33 5.93e-10 Coronary artery disease; LIHC cis rs7072216 0.763 rs2274245 chr10:100175082 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.38 -0.33 5.7e-10 Metabolite levels; LIHC cis rs11628318 0.853 rs7140280 chr14:103026991 C/T cg23461800 chr14:103021989 NA -0.45 -6.36 -0.33 6.56e-10 Platelet count; LIHC cis rs6882046 0.513 rs651666 chr5:88048767 A/G cg22951263 chr5:87985283 NA -0.39 -6.84 -0.35 3.67e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs2404602 0.583 rs12898415 chr15:76574232 C/T cg22467129 chr15:76604101 ETFA -0.39 -6.4 -0.33 5.02e-10 Blood metabolite levels; LIHC cis rs12477438 0.520 rs11677247 chr2:99756358 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.24 0.61 1.91e-36 Chronic sinus infection; LIHC cis rs4930561 0.714 rs7122250 chr11:67946472 T/C cg04465784 chr11:67976953 SUV420H1 -0.3 -5.75 -0.3 1.96e-8 Breast cancer in childhood cancer survivors;IgG glycosylation; LIHC cis rs7592578 0.825 rs12477369 chr2:191455624 G/T cg10560079 chr2:191398806 TMEM194B 0.87 12.19 0.55 1.3e-28 Diastolic blood pressure; LIHC cis rs10170846 0.789 rs972650 chr2:223520287 C/T cg25565276 chr2:223520875 FARSB 0.63 9.32 0.45 1.52e-18 Schizophrenia (inflammation and infection response interaction); LIHC trans rs1814175 0.558 rs5025146 chr11:49795724 C/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.48e-59 Height; LIHC cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg20607798 chr8:58055168 NA 0.68 7.61 0.38 2.64e-13 Developmental language disorder (linguistic errors); LIHC cis rs763121 0.853 rs138704 chr22:39133410 A/G cg06022373 chr22:39101656 GTPBP1 0.7 13.76 0.6 1.4e-34 Menopause (age at onset); LIHC cis rs7534824 0.543 rs61780299 chr1:101403471 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.67 0.38 1.78e-13 Refractive astigmatism; LIHC cis rs61008539 0.741 rs11767322 chr7:867405 A/G cg00475322 chr7:917719 C7orf20 0.56 8.8 0.43 6.73e-17 Perceived unattractiveness to mosquitoes; LIHC cis rs68170813 0.559 rs80307895 chr7:106907781 T/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs7937682 0.632 rs3944619 chr11:111774743 A/G cg09085632 chr11:111637200 PPP2R1B 0.93 13.78 0.6 1.2e-34 Primary sclerosing cholangitis; LIHC cis rs507080 0.733 rs7108144 chr11:118569694 G/A cg04173919 chr11:118528438 PHLDB1 0.33 6.2 0.32 1.64e-9 Serum metabolite levels; LIHC cis rs6748734 1.000 rs11893118 chr2:241828308 C/G cg09990169 chr2:241835740 C2orf54 -0.71 -11.61 -0.53 1.74e-26 Urinary metabolites; LIHC cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg18357526 chr6:26021779 HIST1H4A -0.95 -14.74 -0.62 2.03e-38 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.929 rs2256615 chr2:61679894 C/G cg14146966 chr2:61757674 XPO1 0.46 7.94 0.39 2.91e-14 Tuberculosis; LIHC trans rs6467710 0.590 rs1723108 chr7:137241511 T/C cg04467748 chr15:79760772 KIAA1024 0.41 6.26 0.32 1.18e-9 AIDS progression; LIHC trans rs7668874 0.779 rs7688382 chr4:116814100 T/C cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.49e-29 Menopause (age at onset); LIHC cis rs8103278 1.000 rs8109951 chr19:46289503 C/T cg02376097 chr19:46275166 DMPK -0.44 -6.87 -0.35 2.98e-11 Coronary artery disease; LIHC cis rs6426558 0.537 rs56219094 chr1:227340191 T/C cg10327440 chr1:227177885 CDC42BPA -0.44 -6.78 -0.34 5.21e-11 Neutrophil percentage of white cells; LIHC cis rs155076 1.000 rs261369 chr13:21868420 C/A cg14456004 chr13:21872349 NA -1.09 -11.94 -0.54 1.05e-27 White matter hyperintensity burden; LIHC cis rs6545883 0.868 rs7608483 chr2:61836235 A/C cg14146966 chr2:61757674 XPO1 0.47 8.06 0.4 1.31e-14 Tuberculosis; LIHC cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.91 -0.39 3.5e-14 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13610622 chr10:11504551 USP6NL -0.48 -7.25 -0.36 2.8e-12 Lung function (FEV1/FVC); LIHC trans rs9914544 0.505 rs59633160 chr17:18761396 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.51 -0.33 2.7e-10 Educational attainment (years of education); LIHC cis rs12908161 0.959 rs11637728 chr15:85203392 A/T cg17507749 chr15:85114479 UBE2QP1 0.65 7.31 0.37 1.95e-12 Schizophrenia; LIHC cis rs8180040 0.653 rs6808742 chr3:47051512 G/A cg02527881 chr3:46936655 PTH1R -0.31 -6.02 -0.31 4.49e-9 Colorectal cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18095720 chr14:50160168 KLHDC1 -0.52 -6.15 -0.32 2.14e-9 Systolic blood pressure; LIHC cis rs68170813 0.559 rs4730229 chr7:106925353 A/G cg02696742 chr7:106810147 HBP1 -0.53 -6.04 -0.31 3.95e-9 Coronary artery disease; LIHC trans rs3780486 0.846 rs10758192 chr9:33131651 G/A cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs12497850 1.000 rs10865952 chr3:48744484 A/G cg07636037 chr3:49044803 WDR6 0.82 14.12 0.61 5.43e-36 Parkinson's disease; LIHC cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg18357526 chr6:26021779 HIST1H4A 0.61 8.56 0.42 3.79e-16 Blood metabolite levels; LIHC cis rs17685 0.753 rs10262501 chr7:75668172 G/A cg04610667 chr7:75704037 NA 0.35 6.31 0.32 8.48e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs61677309 0.638 rs58507982 chr11:118146510 C/T cg06090739 chr11:118230722 UBE4A 0.32 6.04 0.31 3.98e-9 Lung cancer in ever smokers; LIHC cis rs12477438 0.798 rs10202452 chr2:99569409 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.76 -11.24 -0.52 3.77e-25 Chronic sinus infection; LIHC cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg21782813 chr7:2030301 MAD1L1 0.43 7.49 0.38 5.86e-13 Schizophrenia; LIHC cis rs867186 0.541 rs78449612 chr20:33457367 G/A cg08999081 chr20:33150536 PIGU 0.64 5.82 0.3 1.38e-8 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs7582720 1.000 rs72928613 chr2:203839628 T/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.38 0.33 5.82e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg12310025 chr6:25882481 NA -0.62 -8.8 -0.43 6.77e-17 Blood metabolite levels; LIHC cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg06634786 chr22:41940651 POLR3H 0.83 8.89 0.43 3.5e-17 Vitiligo; LIHC cis rs35110281 0.748 rs4997353 chr21:45002329 A/C cg21573476 chr21:45109991 RRP1B -0.52 -9.87 -0.47 2.2e-20 Mean corpuscular volume; LIHC cis rs7364180 0.582 rs139568 chr22:42210985 C/T cg03806693 chr22:41940476 POLR3H 0.47 6.44 0.33 4.16e-10 Alzheimer's disease biomarkers; LIHC cis rs2467099 0.679 rs2608882 chr17:73934130 G/A cg08125733 chr17:73851984 WBP2 0.46 5.85 0.3 1.12e-8 Systolic blood pressure; LIHC cis rs9325144 0.650 rs6582624 chr12:38733475 A/T cg26384229 chr12:38710491 ALG10B -0.56 -7.7 -0.38 1.43e-13 Morning vs. evening chronotype; LIHC cis rs2576037 0.583 rs11660085 chr18:44529603 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.71 -11.02 -0.51 2.21e-24 Personality dimensions; LIHC cis rs151997 0.962 rs27475 chr5:50180439 A/C cg06027927 chr5:50259733 NA 0.57 7.59 0.38 3.09e-13 Callous-unemotional behaviour; LIHC cis rs2251381 0.606 rs8129515 chr21:30520167 C/G cg08807101 chr21:30365312 RNF160 0.72 9.6 0.46 1.73e-19 Selective IgA deficiency; LIHC cis rs116248771 0.739 rs76493374 chr3:158345639 G/A cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.77e-10 diarrhoeal disease at age 2; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05348982 chr12:81331012 MIR618;LIN7A -0.39 -6.25 -0.32 1.24e-9 Pancreatic cancer; LIHC cis rs611744 0.631 rs681963 chr8:109255032 C/A cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs2836950 0.565 rs7276046 chr21:40581293 T/C cg11890956 chr21:40555474 PSMG1 -0.47 -7.82 -0.39 6.79e-14 Menarche (age at onset); LIHC cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 9.88 0.47 2e-20 Platelet count; LIHC cis rs801193 0.935 rs2659916 chr7:66151352 C/G cg11764359 chr7:65958608 NA 0.71 10.56 0.5 9.29e-23 Aortic root size; LIHC cis rs10870270 0.956 rs4880405 chr10:133787021 G/A cg17892150 chr10:133769511 PPP2R2D -0.65 -11.65 -0.53 1.18e-26 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.84 8.56 0.42 3.88e-16 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24400517 chr7:139876520 LOC100134229;JHDM1D 0.44 6.26 0.32 1.15e-9 Pancreatic cancer; LIHC cis rs4407350 1.000 rs1475991 chr22:44923160 T/C cg26276947 chr22:44892394 LDOC1L 0.33 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.29 0.45 1.84e-18 Bipolar disorder; LIHC cis rs9486715 0.867 rs2499774 chr6:97006581 C/G cg06623918 chr6:96969491 KIAA0776 -0.87 -15.61 -0.65 7.33e-42 Headache; LIHC cis rs9733 0.596 rs7529998 chr1:150662531 C/T cg13175981 chr1:150552382 MCL1 -0.44 -6.06 -0.31 3.55e-9 Tonsillectomy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17258551 chr19:18077791 KCNN1 0.45 6.29 0.32 9.84e-10 Lung function (FEV1/FVC); LIHC cis rs2282802 0.660 rs4463213 chr5:139545748 G/A cg26211634 chr5:139558579 C5orf32 -0.38 -5.88 -0.3 9.6e-9 Intelligence (multi-trait analysis); LIHC cis rs6598955 0.515 rs61776655 chr1:26541430 T/C cg04990556 chr1:26633338 UBXN11 -0.56 -9.15 -0.44 5.2e-18 Obesity-related traits; LIHC cis rs17685 0.672 rs1639618 chr7:75701987 T/C cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg22105103 chr4:187893119 NA 0.35 8.88 0.43 3.78e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs79149102 0.579 rs8033125 chr15:75374970 G/C cg16226627 chr15:75307476 SCAMP5 0.49 8.6 0.42 2.93e-16 Lung cancer; LIHC cis rs2075165 0.901 rs1043165 chr1:156220056 T/C cg08469215 chr1:156261351 TMEM79 0.37 5.89 0.3 9.45e-9 Tonsillectomy; LIHC cis rs11971779 0.941 rs28395455 chr7:139035986 A/G cg07862535 chr7:139043722 LUC7L2 0.72 10.29 0.49 8.22e-22 Diisocyanate-induced asthma; LIHC cis rs1538970 0.962 rs2487442 chr1:45857176 C/G cg24296786 chr1:45957014 TESK2 0.51 7.77 0.39 9.09e-14 Platelet count; LIHC cis rs826838 1.000 rs11610522 chr12:38687575 C/T cg13010199 chr12:38710504 ALG10B 0.64 7.76 0.39 9.75e-14 Heart rate; LIHC cis rs9768139 0.935 rs10434944 chr7:158116911 C/T cg25566285 chr7:158114605 PTPRN2 -0.25 -7.47 -0.37 6.7e-13 Calcium levels; LIHC cis rs490234 0.812 rs13300639 chr9:128407298 A/G cg14078157 chr9:128172775 NA -0.43 -7.29 -0.37 2.11e-12 Mean arterial pressure; LIHC cis rs9916302 0.851 rs11078907 chr17:37662954 C/T cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC trans rs11098499 0.863 rs6833334 chr4:120504227 C/T cg25214090 chr10:38739885 LOC399744 0.58 9.51 0.46 3.44e-19 Corneal astigmatism; LIHC cis rs4555082 0.874 rs2816620 chr14:105732704 G/T cg10792982 chr14:105748885 BRF1 0.5 6.56 0.33 2.05e-10 Mean platelet volume;Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09070522 chr4:57774717 REST 0.43 6.17 0.32 1.89e-9 Lung function (FEV1/FVC); LIHC cis rs1953600 0.818 rs2152546 chr10:81906384 G/T cg04850286 chr10:81895943 PLAC9 -0.33 -5.79 -0.3 1.58e-8 Sarcoidosis; LIHC cis rs5769765 0.913 rs4824111 chr22:50284305 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.82 10.13 0.48 2.99e-21 Schizophrenia; LIHC cis rs1552244 0.554 rs13081079 chr3:10056348 A/G cg21531657 chr3:10005747 TMEM111 0.39 5.76 0.3 1.92e-8 Alzheimer's disease; LIHC cis rs62244186 0.659 rs9819766 chr3:44520980 G/C cg25364880 chr3:44379878 C3orf23 0.6 8.55 0.42 4.24e-16 Depressive symptoms; LIHC cis rs1707322 0.752 rs4660880 chr1:46111040 C/T cg06784218 chr1:46089804 CCDC17 0.4 7.22 0.36 3.4e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg12310025 chr6:25882481 NA -0.68 -8.78 -0.43 7.78e-17 Intelligence (multi-trait analysis); LIHC trans rs11039798 0.778 rs7944523 chr11:48911019 G/A cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC cis rs1577917 0.771 rs9362230 chr6:86305013 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.86 -0.39 5.13e-14 Response to antipsychotic treatment; LIHC cis rs763121 0.853 rs2413544 chr22:39059404 A/C cg14440974 chr22:39074834 NA -0.43 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC trans rs7246657 0.943 rs1382357 chr19:37977609 G/A cg10208301 chr11:6592745 DNHD1 0.45 6.45 0.33 3.73e-10 Coronary artery calcification; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg05734877 chr13:111299462 CARS2 0.44 6.22 0.32 1.42e-9 Alopecia areata; LIHC cis rs694739 0.595 rs11606015 chr11:64136877 C/G cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.02e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs10927875 0.864 rs12744578 chr1:16173110 A/T cg07117364 chr1:16154769 NA -0.38 -5.72 -0.3 2.37e-8 Dilated cardiomyopathy; LIHC cis rs4478037 0.822 rs9827863 chr3:33118951 C/T cg27203090 chr3:33138513 GLB1;TMPPE 0.52 6.5 0.33 2.76e-10 Major depressive disorder; LIHC cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg20887711 chr4:1340912 KIAA1530 0.47 7.13 0.36 6.06e-12 Obesity-related traits; LIHC cis rs7223966 1.000 rs9893348 chr17:61676534 G/T cg05941027 chr17:61774174 LIMD2 0.31 6.0 0.31 5.12e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1799949 0.965 rs4239149 chr17:41328095 A/G cg19454999 chr17:41278357 BRCA1;NBR2 -0.41 -5.93 -0.31 7.47e-9 Menopause (age at onset); LIHC cis rs4474465 0.850 rs10793328 chr11:78256868 A/G cg02023728 chr11:77925099 USP35 -0.37 -6.44 -0.33 4.1e-10 Alzheimer's disease (survival time); LIHC cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.53 0.53 3.24e-26 Alzheimer's disease; LIHC cis rs2932538 0.922 rs6659677 chr1:113087076 G/C cg22162597 chr1:113214053 CAPZA1 0.7 10.71 0.5 2.76e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs4129767 0.869 rs4969142 chr17:76398304 G/A cg05887092 chr17:76393375 PGS1 0.35 6.69 0.34 9.22e-11 HDL cholesterol; LIHC cis rs7264396 0.790 rs6121018 chr20:34249060 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.45 -0.53 6.66e-26 Total cholesterol levels; LIHC cis rs5769765 0.862 rs138897 chr22:50231067 T/C cg02269571 chr22:50332266 NA -0.61 -8.43 -0.41 1.01e-15 Schizophrenia; LIHC cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg11502198 chr6:26597334 ABT1 0.64 10.12 0.48 3.23e-21 Intelligence (multi-trait analysis); LIHC cis rs10791097 0.739 rs12279359 chr11:130730544 G/A cg14779329 chr11:130786720 SNX19 0.39 5.95 0.31 6.72e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6815814 0.950 rs5743580 chr4:38804405 C/T cg06935464 chr4:38784597 TLR10 0.48 7.38 0.37 1.23e-12 Breast cancer; LIHC cis rs7829975 0.688 rs7817376 chr8:8380530 C/T cg06636001 chr8:8085503 FLJ10661 -0.5 -8.06 -0.4 1.33e-14 Mood instability; LIHC cis rs3749237 0.595 rs10865955 chr3:49499829 G/A cg03060546 chr3:49711283 APEH 0.64 10.52 0.49 1.31e-22 Resting heart rate; LIHC cis rs963731 0.649 rs297153 chr2:39326835 C/G cg04010122 chr2:39346883 SOS1 -0.7 -6.25 -0.32 1.25e-9 Corticobasal degeneration; LIHC cis rs7589728 0.563 rs2292868 chr2:88475047 A/G cg07952391 chr2:88470173 THNSL2 -0.86 -8.29 -0.41 2.63e-15 Plasma clusterin levels; LIHC cis rs2204008 0.627 rs10878488 chr12:38148666 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.78 0.3 1.68e-8 Bladder cancer; LIHC cis rs61008539 0.586 rs6959154 chr7:856320 C/T cg00934597 chr7:893267 UNC84A -0.63 -9.09 -0.44 8e-18 Perceived unattractiveness to mosquitoes; LIHC cis rs13161895 0.702 rs74507840 chr5:179487430 G/A cg02702477 chr5:179499311 RNF130 1.02 13.41 0.59 2.94e-33 LDL cholesterol; LIHC cis rs597539 0.652 rs553875 chr11:68695144 T/G cg06028808 chr11:68637592 NA 0.45 5.78 0.3 1.65e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7666738 0.830 rs4502686 chr4:98765117 T/C cg05340658 chr4:99064831 C4orf37 0.64 11.59 0.53 2.03e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs12477438 0.520 rs6717729 chr2:99756941 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.61 0.64 7.81e-42 Chronic sinus infection; LIHC cis rs798766 1.000 rs11729657 chr4:1737585 T/C cg21231739 chr4:1642635 FAM53A -0.37 -6.07 -0.31 3.49e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs11971779 0.584 rs34762928 chr7:139113168 T/A cg07862535 chr7:139043722 LUC7L2 0.59 10.29 0.49 8.39e-22 Diisocyanate-induced asthma; LIHC cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.82 8.68 0.43 1.59e-16 Platelet count; LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg24846343 chr22:24311635 DDTL 0.5 8.37 0.41 1.49e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.61 0.34 1.46e-10 Bipolar disorder; LIHC trans rs2243480 1.000 rs13220979 chr7:65363204 G/A cg10756647 chr7:56101905 PSPH 1.09 13.38 0.59 4.07e-33 Diabetic kidney disease; LIHC trans rs62103177 0.789 rs7242289 chr18:77603291 C/T cg05926928 chr17:57297772 GDPD1 1.23 13.28 0.58 9.61e-33 Opioid sensitivity; LIHC cis rs4808199 0.947 rs10404728 chr19:19595014 C/T cg03709012 chr19:19516395 GATAD2A 1.08 19.2 0.72 2.97e-56 Nonalcoholic fatty liver disease; LIHC cis rs295140 0.605 rs3769471 chr2:201195403 G/A cg23649088 chr2:200775458 C2orf69 -0.44 -6.13 -0.31 2.36e-9 QT interval; LIHC cis rs6545883 0.859 rs7561672 chr2:61519094 G/A cg15711740 chr2:61764176 XPO1 0.42 5.78 0.3 1.69e-8 Tuberculosis; LIHC cis rs12220238 1.000 rs11000905 chr10:75925532 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs34779708 0.966 rs12762493 chr10:35471873 G/A cg03585969 chr10:35415529 CREM 0.79 11.75 0.54 5.18e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6665290 0.669 rs3768419 chr1:227173477 C/G cg10327440 chr1:227177885 CDC42BPA -1.11 -23.83 -0.79 1.15e-74 Myeloid white cell count; LIHC cis rs8081395 0.805 rs1295927 chr17:57929535 A/G cg13753209 chr17:57696993 CLTC 0.45 7.08 0.36 8.43e-12 White blood cell count; LIHC cis rs2153535 0.580 rs9328479 chr6:8519646 A/G cg07606381 chr6:8435919 SLC35B3 0.8 11.94 0.54 1.07e-27 Motion sickness; LIHC cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg16822855 chr3:40428330 ENTPD3 0.34 6.28 0.32 1.05e-9 Renal cell carcinoma; LIHC cis rs736408 0.608 rs4687657 chr3:52852538 G/T cg11645453 chr3:52864694 ITIH4 0.29 7.67 0.38 1.87e-13 Bipolar disorder; LIHC cis rs503341 0.756 rs626333 chr11:63591861 C/T cg04362095 chr11:63592001 C11orf84 -0.67 -13.44 -0.59 2.27e-33 Pulse pressure; LIHC cis rs7635838 0.654 rs346086 chr3:11272932 G/T cg00170343 chr3:11313890 ATG7 0.54 8.41 0.41 1.16e-15 HDL cholesterol; LIHC cis rs9942416 0.559 rs7734618 chr5:75033762 A/T cg19683494 chr5:74908142 NA -0.56 -6.54 -0.33 2.26e-10 Age-related disease endophenotypes; LIHC cis rs798554 0.757 rs1182172 chr7:2878103 G/A cg04166393 chr7:2884313 GNA12 0.45 5.72 0.3 2.3e-8 Height; LIHC cis rs3106136 0.649 rs4699440 chr4:95306151 T/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs1577917 1.000 rs12204365 chr6:86700532 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.63 -0.46 1.43e-19 Response to antipsychotic treatment; LIHC cis rs9486715 0.867 rs2499774 chr6:97006581 C/G cg18709589 chr6:96969512 KIAA0776 -0.33 -5.84 -0.3 1.19e-8 Headache; LIHC cis rs422249 0.547 rs102275 chr11:61557803 T/C cg07689907 chr11:61582574 FADS1 0.4 6.02 0.31 4.62e-9 Trans fatty acid levels; LIHC cis rs600806 0.888 rs461200 chr1:109855404 G/A cg23091122 chr1:110024289 SYPL2 -0.45 -5.9 -0.3 8.75e-9 Intelligence (multi-trait analysis); LIHC cis rs1448094 0.512 rs7313035 chr12:86250100 C/G cg02569458 chr12:86230093 RASSF9 0.46 6.19 0.32 1.76e-9 Major depressive disorder; LIHC cis rs240764 0.817 rs239207 chr6:101137765 A/C cg09795085 chr6:101329169 ASCC3 0.53 7.24 0.36 3.04e-12 Neuroticism; LIHC cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg04944784 chr2:26401820 FAM59B 0.74 9.11 0.44 6.83e-18 Gut microbiome composition (summer); LIHC cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.7 0.57 1.59e-30 Alzheimer's disease; LIHC cis rs6500602 0.561 rs62039231 chr16:4519548 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 6.28 0.32 1.01e-9 Schizophrenia; LIHC cis rs4699052 0.963 rs11943325 chr4:104178393 T/C cg16532752 chr4:104119610 CENPE -0.38 -6.07 -0.31 3.32e-9 Testicular germ cell tumor; LIHC trans rs2727020 0.521 rs11040408 chr11:49534880 A/T cg03929089 chr4:120376271 NA 0.68 10.03 0.48 6.51e-21 Coronary artery disease; LIHC trans rs4714291 1.000 rs1100103 chr6:40040424 T/C cg02267698 chr19:7991119 CTXN1 0.39 6.31 0.32 8.56e-10 Strep throat; LIHC cis rs2404602 0.583 rs2456076 chr15:76557553 T/G cg03037974 chr15:76606532 NA -0.84 -20.67 -0.75 3.69e-62 Blood metabolite levels; LIHC cis rs6951245 0.554 rs10246354 chr7:1132456 C/T cg22907277 chr7:1156413 C7orf50 0.93 8.8 0.43 6.73e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2834188 1.000 rs2096464 chr21:34686049 G/T cg14352951 chr21:34696688 IFNAR1 -0.47 -6.46 -0.33 3.51e-10 Narcolepsy; LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg09455208 chr3:40491958 NA 0.41 8.27 0.41 3.08e-15 Renal cell carcinoma; LIHC cis rs6598955 0.640 rs6667826 chr1:26531408 T/C cg00852783 chr1:26633632 UBXN11 0.49 8.06 0.4 1.29e-14 Obesity-related traits; LIHC cis rs6684514 1.000 rs12134983 chr1:156290409 T/C cg16558208 chr1:156270281 VHLL 0.55 10.39 0.49 3.56e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9649213 0.593 rs10953255 chr7:97923198 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.95 -0.31 6.62e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg05590025 chr7:65112418 INTS4L2 -0.63 -7.05 -0.36 9.75e-12 Diabetic kidney disease; LIHC cis rs941408 0.515 rs12610096 chr19:2778129 C/T cg02580895 chr19:2754563 NA -0.46 -6.76 -0.34 6.09e-11 Total cholesterol levels; LIHC cis rs867186 0.614 rs116707649 chr20:33424671 G/A cg08999081 chr20:33150536 PIGU 0.63 5.94 0.31 6.97e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07631383 chr7:131012765 MKLN1 0.45 6.38 0.33 5.84e-10 Pancreatic cancer; LIHC cis rs798554 0.757 rs1182172 chr7:2878103 G/A cg13628971 chr7:2884303 GNA12 0.51 6.8 0.34 4.75e-11 Height; LIHC cis rs7833986 0.501 rs72653917 chr8:56892844 T/A cg23139584 chr8:56987506 RPS20;SNORD54 0.86 8.61 0.42 2.72e-16 Height; LIHC cis rs10744422 1.000 rs7972447 chr12:123354545 C/G cg07706471 chr12:123319906 HIP1R -0.55 -6.9 -0.35 2.55e-11 Schizophrenia; LIHC cis rs2412488 1.000 rs1481824 chr4:54241402 C/T cg22241045 chr4:54363911 LNX1 -0.46 -7.24 -0.36 2.98e-12 DNA methylation (variation); LIHC cis rs7149337 0.805 rs7146561 chr14:51608889 C/G cg23942311 chr14:51606299 NA 0.35 7.33 0.37 1.7e-12 Cancer; LIHC cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7927771 0.864 rs4752999 chr11:47428565 C/T cg18512352 chr11:47633146 NA -0.25 -5.87 -0.3 1.05e-8 Subjective well-being; LIHC cis rs743757 0.878 rs1467913 chr3:50525017 G/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.39 5.92 0.3 7.98e-9 Diastolic blood pressure; LIHC cis rs12477438 0.520 rs6743355 chr2:99732360 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.05 0.6 1.02e-35 Chronic sinus infection; LIHC cis rs747782 0.583 rs11039300 chr11:47587062 G/A cg20307385 chr11:47447363 PSMC3 0.59 7.04 0.36 1.08e-11 Intraocular pressure; LIHC cis rs12477438 0.520 rs11123762 chr2:99727789 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.05 0.6 1.02e-35 Chronic sinus infection; LIHC cis rs2842992 0.830 rs2758312 chr6:160153452 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.54 9.53 0.46 2.92e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs8103278 0.507 rs2041975 chr19:46238555 T/C cg14061069 chr19:46274453 DMPK 0.69 12.67 0.57 1.92e-30 Coronary artery disease; LIHC cis rs611744 0.839 rs638238 chr8:109169152 A/G cg21045802 chr8:109455806 TTC35 0.57 9.86 0.47 2.31e-20 Dupuytren's disease; LIHC cis rs2180341 0.781 rs877102 chr6:127587086 T/C cg24812749 chr6:127587940 RNF146 0.67 9.79 0.47 4.14e-20 Breast cancer; LIHC cis rs611744 0.967 rs631031 chr8:109190032 G/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs7617773 0.780 rs4130522 chr3:48352313 G/A cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs8177253 0.514 rs6790668 chr3:133442481 T/A cg16262614 chr3:133464971 TF 0.35 7.98 0.4 2.26e-14 Iron status biomarkers; LIHC cis rs3770081 1.000 rs2241435 chr2:86360916 C/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.69 -7.52 -0.38 4.84e-13 Facial emotion recognition (sad faces); LIHC cis rs1499614 1.000 rs60326618 chr7:66166358 G/A cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs1555322 0.530 rs2425047 chr20:33871675 G/T cg07134254 chr20:33865797 NA -0.51 -6.24 -0.32 1.27e-9 Attention deficit hyperactivity disorder; LIHC cis rs8060686 0.641 rs12447931 chr16:68179195 C/T cg05110241 chr16:68378359 PRMT7 -0.59 -6.55 -0.33 2.06e-10 HDL cholesterol;Metabolic syndrome; LIHC trans rs2727020 0.521 rs7946190 chr11:49521964 T/A cg18944383 chr4:111397179 ENPEP -0.35 -8.15 -0.4 7.15e-15 Coronary artery disease; LIHC cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg02290350 chr8:58132656 NA 0.39 7.94 0.39 2.95e-14 Developmental language disorder (linguistic errors); LIHC cis rs1691799 0.867 rs961049 chr12:66762591 A/C cg16791601 chr12:66731901 HELB 0.43 8.99 0.44 1.75e-17 White blood cell count (basophil); LIHC cis rs2832191 1.000 rs2832190 chr21:30488226 G/A cg08807101 chr21:30365312 RNF160 -0.59 -9.3 -0.45 1.74e-18 Dental caries; LIHC cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg22800045 chr5:56110881 MAP3K1 0.67 8.69 0.43 1.56e-16 Initial pursuit acceleration; LIHC cis rs11583043 1.000 rs3861734 chr1:101489461 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.09 0.4 1.02e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs1974653 0.781 rs175163 chr22:20113777 T/C cg20152630 chr19:46405944 MYPOP 0.46 6.08 0.31 3.26e-9 Schizophrenia; LIHC cis rs8141529 0.687 rs6005867 chr22:29165120 T/C cg15103426 chr22:29168792 CCDC117 0.66 11.14 0.52 8.63e-25 Lymphocyte counts; LIHC cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC trans rs2270927 0.790 rs6874435 chr5:75574855 A/G cg13563193 chr19:33072644 PDCD5 0.89 9.63 0.46 1.42e-19 Mean corpuscular volume; LIHC cis rs11190604 1.000 rs11292 chr10:102313607 A/G cg07080220 chr10:102295463 HIF1AN 0.5 7.08 0.36 8.06e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9768139 0.708 rs921615 chr7:158117935 A/G cg25566285 chr7:158114605 PTPRN2 0.22 5.97 0.31 6.03e-9 Calcium levels; LIHC cis rs875971 0.660 rs2013222 chr7:66035936 C/G cg18876405 chr7:65276391 NA -0.42 -7.28 -0.37 2.27e-12 Aortic root size; LIHC cis rs5769765 0.955 rs7511159 chr22:50307896 A/G cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.21e-16 Schizophrenia; LIHC cis rs6942756 1.000 rs2141075 chr7:128877305 C/T cg02491457 chr7:128862824 NA 0.72 11.59 0.53 1.96e-26 White matter hyperintensity burden; LIHC cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg12373951 chr3:133503437 NA 0.43 7.19 0.36 4.11e-12 Iron status biomarkers; LIHC cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg08888203 chr3:10149979 C3orf24 0.51 6.11 0.31 2.77e-9 Alzheimer's disease; LIHC cis rs11971779 0.793 rs4732366 chr7:139027845 G/C cg07862535 chr7:139043722 LUC7L2 0.67 11.5 0.53 4.25e-26 Diisocyanate-induced asthma; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg09455208 chr3:40491958 NA -0.36 -7.38 -0.37 1.25e-12 Renal cell carcinoma; LIHC cis rs7208859 0.623 rs9896603 chr17:29078512 C/G cg13385521 chr17:29058706 SUZ12P 0.81 7.96 0.4 2.64e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1043515 0.748 rs11657530 chr17:36942814 T/C cg09592244 chr17:37024020 NA 0.41 6.99 0.35 1.46e-11 Height; LIHC trans rs72960926 1.000 rs72950597 chr6:74921367 T/C cg07247405 chr1:2484626 LOC115110 0.55 6.53 0.33 2.37e-10 Metabolite levels (MHPG); LIHC cis rs1904096 0.506 rs28522293 chr4:95167087 A/G cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.23 -0.45 2.99e-18 Type 2 diabetes; LIHC cis rs6893300 0.542 rs3797774 chr5:179193970 C/T cg14593053 chr5:179126677 CANX 0.45 8.14 0.4 7.46e-15 Resting heart rate; LIHC cis rs10416265 0.528 rs28654374 chr19:33613610 G/A cg27124370 chr19:33622961 WDR88 0.49 6.84 0.35 3.74e-11 Bone properties (heel); LIHC cis rs2073300 0.609 rs6137910 chr20:23346515 C/G cg16736954 chr20:23401023 NAPB 0.73 8.63 0.42 2.36e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg11494091 chr17:61959527 GH2 0.44 8.08 0.4 1.1e-14 Prudent dietary pattern; LIHC cis rs8056893 0.686 rs10775304 chr16:68411162 C/T cg02226672 chr16:68398533 SMPD3 0.42 5.9 0.3 8.83e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC trans rs1973993 0.691 rs553785 chr1:96895325 G/A cg10631902 chr5:14652156 NA 0.37 10.08 0.48 4.43e-21 Weight; LIHC cis rs5758659 0.729 rs134866 chr22:42650663 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.31 -6.02 -0.31 4.46e-9 Cognitive function; LIHC trans rs10242455 0.557 rs77997620 chr7:99070415 G/T cg09045935 chr12:6379348 NA 0.84 6.92 0.35 2.28e-11 Blood metabolite levels; LIHC trans rs7613875 0.620 rs17657664 chr3:50032008 T/G cg21659725 chr3:3221576 CRBN 0.55 8.25 0.41 3.57e-15 Body mass index; LIHC trans rs8073060 0.586 rs9649 chr17:34050934 C/T cg19694781 chr19:47549865 TMEM160 1.22 12.75 0.57 9.9e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg18769103 chr1:236445447 ERO1LB 0.4 6.47 0.33 3.41e-10 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs9399137 0.507 rs6923512 chr6:135335268 A/G cg24558204 chr6:135376177 HBS1L -0.61 -10.31 -0.49 6.75e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs11098499 0.657 rs4463052 chr4:120313258 T/C cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC trans rs4356975 0.563 rs4535394 chr4:69988453 C/T cg18043070 chr17:72199725 RPL38 0.4 6.14 0.32 2.35e-9 Obesity-related traits; LIHC cis rs9399135 0.967 rs4637662 chr6:135298158 T/C cg22676075 chr6:135203613 NA 0.4 6.47 0.33 3.48e-10 Red blood cell count; LIHC cis rs77861329 1.000 rs28452586 chr3:52176007 A/G cg08692210 chr3:52188851 WDR51A 0.85 8.38 0.41 1.35e-15 Macrophage inflammatory protein 1b levels; LIHC cis rs7124681 0.565 rs2203712 chr11:47534964 T/C cg20307385 chr11:47447363 PSMC3 0.8 12.14 0.55 1.92e-28 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs12142240 0.659 rs111723629 chr1:46853361 G/T cg14993813 chr1:46806288 NSUN4 -0.66 -5.94 -0.31 6.85e-9 Menopause (age at onset); LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg02993280 chr1:107599747 PRMT6 -0.69 -11.16 -0.52 6.98e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9473924 0.505 rs7738924 chr6:50850600 C/T cg14470998 chr6:50812995 TFAP2B 0.94 10.91 0.51 5.57e-24 Body mass index; LIHC cis rs7843479 0.965 rs1564305 chr8:21803816 A/C cg17168535 chr8:21777572 XPO7 0.41 6.55 0.33 2.17e-10 Mean corpuscular volume; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg21747090 chr2:27597821 SNX17 -0.47 -7.16 -0.36 5.01e-12 Total body bone mineral density; LIHC cis rs4589502 0.925 rs57729347 chr15:67136438 G/A cg12317470 chr15:67143691 NA 0.64 7.26 0.37 2.61e-12 Lung cancer (smoking interaction); LIHC cis rs3743266 0.507 rs62003261 chr15:60761489 T/C cg22293140 chr15:60689852 ANXA2 -0.62 -5.85 -0.3 1.14e-8 Menarche (age at onset); LIHC cis rs4555082 0.874 rs2816626 chr14:105735425 G/A cg06808227 chr14:105710500 BRF1 -0.55 -7.11 -0.36 6.98e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs11212260 0.512 rs74650296 chr11:107131138 G/A cg25435332 chr11:107328525 CWF19L2 0.75 7.21 0.36 3.66e-12 IgG glycosylation; LIHC cis rs477692 0.673 rs1970197 chr10:131359588 C/T cg05714579 chr10:131428358 MGMT 0.38 5.97 0.31 5.87e-9 Response to temozolomide; LIHC cis rs7208859 0.673 rs9915139 chr17:29158515 A/G cg14067834 chr17:29058358 SUZ12P 0.64 6.24 0.32 1.28e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17345786 0.906 rs56171035 chr3:101111108 G/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.57 7.09 0.36 7.92e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs7903847 0.642 rs11814021 chr10:99158386 A/G cg08345082 chr10:99160200 RRP12 -0.4 -6.64 -0.34 1.27e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg03735888 chr19:58951602 ZNF132 0.39 6.91 0.35 2.31e-11 Uric acid clearance; LIHC cis rs240764 0.658 rs13196803 chr6:101188052 A/T cg09795085 chr6:101329169 ASCC3 -0.54 -7.81 -0.39 7.26e-14 Neuroticism; LIHC cis rs6831352 0.734 rs2602857 chr4:100030318 G/A cg12011299 chr4:100065546 ADH4 0.56 9.87 0.47 2.2e-20 Alcohol dependence; LIHC trans rs75804782 0.521 rs55690022 chr2:239407783 C/T cg01134436 chr17:81009848 B3GNTL1 0.83 6.94 0.35 1.94e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs3859192 0.599 rs34933056 chr17:38162983 G/A cg17467752 chr17:38218738 THRA -0.51 -8.64 -0.42 2.21e-16 White blood cell count; LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.51 -7.36 -0.37 1.37e-12 Lymphocyte counts; LIHC trans rs6600671 1.000 rs10903161 chr1:121178741 A/T cg09829573 chr1:144692074 NBPF9 -0.44 -8.06 -0.4 1.26e-14 Hip geometry; LIHC trans rs116095464 0.558 rs28729548 chr5:229025 C/T cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs10751667 1.000 rs6597965 chr11:964476 A/G cg10932868 chr11:921992 NA 0.36 6.77 0.34 5.46e-11 Alzheimer's disease (late onset); LIHC cis rs11758351 0.660 rs11759904 chr6:26231443 T/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs72627123 0.656 rs6574169 chr14:74637178 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 -0.89 -8.51 -0.42 5.4e-16 Morning vs. evening chronotype; LIHC cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg18876405 chr7:65276391 NA -0.55 -9.31 -0.45 1.65e-18 Aortic root size; LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.57 8.27 0.41 3.11e-15 Lymphocyte counts; LIHC cis rs9902453 0.967 rs17825877 chr17:28515188 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.16 0.44 4.93e-18 Coffee consumption (cups per day); LIHC cis rs4888262 0.508 rs12598701 chr16:74539904 G/A cg01733217 chr16:74700730 RFWD3 0.75 14.45 0.62 2.88e-37 Testicular germ cell tumor; LIHC cis rs4654899 0.758 rs35913932 chr1:21423025 G/T cg08539965 chr1:21396338 EIF4G3 0.33 5.75 0.3 1.98e-8 Superior frontal gyrus grey matter volume; LIHC cis rs875971 1.000 rs4717292 chr7:65895598 G/A cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs2645694 0.626 rs2645709 chr4:77824474 G/A cg03477792 chr4:77819574 ANKRD56 0.58 8.46 0.42 7.67e-16 Emphysema distribution in smoking; LIHC cis rs881375 0.967 rs7875829 chr9:123660398 A/G cg14580859 chr9:123691850 NA 0.39 6.76 0.34 5.9e-11 Rheumatoid arthritis; LIHC cis rs4843747 0.708 rs11866437 chr16:88072279 A/G cg07560587 chr16:88016574 BANP -0.42 -6.6 -0.34 1.54e-10 Menopause (age at onset); LIHC cis rs6547741 1.000 rs11127071 chr2:27838058 C/A cg27432699 chr2:27873401 GPN1 0.71 11.6 0.53 1.87e-26 Oral cavity cancer; LIHC cis rs8062405 0.755 rs1074631 chr16:28554108 A/G cg00204512 chr16:28754710 NA -0.39 -6.69 -0.34 9.1e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6459788 0.502 rs9692347 chr7:157232659 C/T cg06271696 chr7:157225062 NA -0.53 -9.91 -0.47 1.59e-20 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs6426558 0.537 rs7523167 chr1:227365304 G/A cg10327440 chr1:227177885 CDC42BPA -0.44 -6.77 -0.34 5.65e-11 Neutrophil percentage of white cells; LIHC cis rs3762637 0.941 rs9873842 chr3:122135331 A/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18921183 chr12:6602631 NCAPD2;MRPL51 -0.49 -6.26 -0.32 1.17e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs11098499 0.954 rs17006190 chr4:120418838 C/G cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs4700695 1.000 rs111340 chr5:65420285 C/A cg21114390 chr5:65439923 SFRS12 -0.52 -7.03 -0.36 1.14e-11 Facial morphology (factor 19); LIHC cis rs8180040 0.874 rs11130123 chr3:47285912 A/G cg02527881 chr3:46936655 PTH1R -0.32 -6.22 -0.32 1.42e-9 Colorectal cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg22156267 chr12:110152166 C12orf34 -0.49 -6.1 -0.31 2.79e-9 Systolic blood pressure; LIHC cis rs9303280 0.773 rs12949100 chr17:38057189 G/A cg11212589 chr17:38028394 ZPBP2 0.36 7.38 0.37 1.23e-12 Self-reported allergy; LIHC cis rs2050392 0.557 rs306588 chr10:30723593 G/A cg18806716 chr10:30721971 MAP3K8 -0.41 -5.85 -0.3 1.14e-8 Inflammatory bowel disease; LIHC cis rs12986413 0.624 rs3786970 chr19:2141150 C/G cg09261902 chr19:2140048 AP3D1 0.39 6.63 0.34 1.32e-10 Height; LIHC cis rs12744310 0.830 rs12045184 chr1:41799611 G/A cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs72627123 0.867 rs73301485 chr14:74468643 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.63 0.42 2.42e-16 Morning vs. evening chronotype; LIHC cis rs6565180 0.962 rs6565183 chr16:30382755 T/C cg17640201 chr16:30407289 ZNF48 -0.77 -13.07 -0.58 6.09e-32 Tonsillectomy; LIHC cis rs34779708 0.966 rs34605125 chr10:35411246 A/G cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12477438 0.501 rs2632284 chr2:99775865 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.24 24.75 0.8 3.3e-78 Chronic sinus infection; LIHC cis rs9911578 1.000 rs2009948 chr17:56611920 A/C cg12560992 chr17:57184187 TRIM37 -0.97 -17.72 -0.69 2.61e-50 Intelligence (multi-trait analysis); LIHC cis rs7707921 0.881 rs7733122 chr5:81351443 C/T cg15871215 chr5:81402204 ATG10 -0.62 -5.98 -0.31 5.48e-9 Breast cancer; LIHC cis rs12701220 0.655 rs7799656 chr7:1140515 C/T cg04025307 chr7:1156635 C7orf50 0.56 7.53 0.38 4.63e-13 Bronchopulmonary dysplasia; LIHC cis rs4819052 0.851 rs13050359 chr21:46672671 T/G cg22633049 chr21:46681294 NA -0.37 -6.46 -0.33 3.6e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17135955 chr4:83848031 LIN54 0.32 6.17 0.32 1.95e-9 Pancreatic cancer; LIHC cis rs2191566 0.959 rs7255623 chr19:44510906 G/C cg20607764 chr19:44506953 ZNF230 -0.45 -7.51 -0.38 5.32e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs13064411 0.696 rs3732803 chr3:113211957 T/C cg18753928 chr3:113234510 CCDC52 -0.42 -6.04 -0.31 4.11e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs10876993 0.890 rs7963927 chr12:58046272 T/G cg18357645 chr12:58087776 OS9 0.5 8.05 0.4 1.38e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs904251 0.861 rs1776456 chr6:37484698 C/G cg01843034 chr6:37503916 NA -0.47 -7.66 -0.38 1.92e-13 Cognitive performance; LIHC cis rs6952808 0.595 rs3800917 chr7:2167939 A/G cg02951883 chr7:2050386 MAD1L1 0.65 10.56 0.5 9.71e-23 Bipolar disorder and schizophrenia; LIHC cis rs7829975 0.564 rs2921057 chr8:8318667 C/T cg14343924 chr8:8086146 FLJ10661 0.51 6.46 0.33 3.52e-10 Mood instability; LIHC cis rs600806 0.850 rs4970751 chr1:109896600 A/C cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs3823572 0.542 rs11767663 chr7:133630596 T/C cg03336402 chr7:133662267 EXOC4 0.48 5.87 0.3 1.05e-8 Intelligence (multi-trait analysis); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg17687970 chr8:22462467 KIAA1967 -0.49 -6.63 -0.34 1.29e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs72781680 0.950 rs56128748 chr2:24126809 T/G cg08917208 chr2:24149416 ATAD2B 0.83 7.71 0.38 1.37e-13 Lymphocyte counts; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs7129556 0.520 rs7943055 chr11:77261051 C/T cg03570279 chr11:77446074 RSF1 -0.35 -6.55 -0.33 2.09e-10 Weight loss (gastric bypass surgery); LIHC cis rs1046896 0.739 rs28459016 chr17:80741194 G/A cg19500275 chr17:80737654 TBCD 0.51 7.29 0.37 2.18e-12 Glycated hemoglobin levels; LIHC cis rs7223966 1.000 rs8067064 chr17:61825984 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.84 0.35 3.73e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs921968 0.643 rs2556384 chr2:219532903 C/T cg17980119 chr2:219472607 PLCD4 -0.34 -5.75 -0.3 2e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2115630 0.645 rs1107179 chr15:85198362 A/C cg11189052 chr15:85197271 WDR73 0.53 8.04 0.4 1.49e-14 P wave terminal force; LIHC cis rs4713118 0.621 rs4713134 chr6:28034121 T/C cg16479474 chr6:28041457 NA 0.47 6.96 0.35 1.73e-11 Parkinson's disease; LIHC cis rs6502050 0.842 rs62079996 chr17:80076862 A/G cg11859384 chr17:80120422 CCDC57 0.43 5.9 0.3 8.52e-9 Life satisfaction; LIHC cis rs4319547 0.585 rs10846792 chr12:122882374 T/C cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.41 -0.37 1.01e-12 Body mass index; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg11494091 chr17:61959527 GH2 0.43 7.68 0.38 1.72e-13 Prudent dietary pattern; LIHC cis rs7927592 0.731 rs10896350 chr11:68386373 A/C cg01657329 chr11:68192670 LRP5 -0.5 -7.33 -0.37 1.64e-12 Total body bone mineral density; LIHC trans rs2096176 0.530 rs35769796 chr10:26303714 C/A cg01396774 chr2:218299024 DIRC3 -0.31 -6.2 -0.32 1.58e-9 Obesity-related traits; LIHC cis rs1008375 1.000 rs1860597 chr4:17657650 C/T cg02297831 chr4:17616191 MED28 0.5 7.83 0.39 6.02e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2727020 0.553 rs11040400 chr11:49518296 C/A cg03929089 chr4:120376271 NA -0.85 -16.05 -0.66 1.38e-43 Coronary artery disease; LIHC cis rs9814567 0.806 rs55835132 chr3:134325256 T/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.8 -0.3 1.53e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24412469 chr1:200590040 KIF14 0.47 6.78 0.34 5.45e-11 Lung function (FEV1/FVC); LIHC cis rs9560113 0.843 rs9555808 chr13:112181284 A/T cg14154082 chr13:112174009 NA 0.3 6.39 0.33 5.52e-10 Menarche (age at onset); LIHC cis rs2952156 0.916 rs903506 chr17:37879762 G/A cg00129232 chr17:37814104 STARD3 -0.51 -9.35 -0.45 1.17e-18 Asthma; LIHC cis rs1559088 0.948 rs10410778 chr19:33592301 C/A cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2180341 0.960 rs6913424 chr6:127707010 A/C cg24812749 chr6:127587940 RNF146 1.04 15.96 0.65 3.03e-43 Breast cancer; LIHC cis rs10149470 0.549 rs9652403 chr14:104036024 G/C cg24130564 chr14:104152367 KLC1 -0.6 -10.77 -0.5 1.8e-23 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs10911232 0.507 rs6672306 chr1:183058898 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 7.81e-23 Hypertriglyceridemia; LIHC cis rs9341808 0.617 rs9294170 chr6:80814080 A/G cg08355045 chr6:80787529 NA 0.38 7.94 0.39 2.96e-14 Sitting height ratio; LIHC cis rs2242116 0.743 rs11719795 chr3:46951935 T/C cg02527881 chr3:46936655 PTH1R -0.45 -8.83 -0.43 5.47e-17 Birth weight; LIHC cis rs2228479 0.717 rs12917681 chr16:89810941 C/A cg04013166 chr16:89971882 TCF25 0.47 6.02 0.31 4.48e-9 Skin colour saturation; LIHC cis rs67311347 0.956 rs12633446 chr3:40505661 G/A cg24209194 chr3:40518798 ZNF619 -0.54 -8.06 -0.4 1.26e-14 Renal cell carcinoma; LIHC cis rs35883536 0.551 rs6666607 chr1:101032368 A/G cg14515779 chr1:101123966 NA 0.42 5.75 0.3 2.01e-8 Monocyte count; LIHC cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg26119090 chr2:26468346 HADHA;HADHB -1.05 -16.2 -0.66 3.38e-44 Gut microbiome composition (summer); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19791253 chr1:203595809 ATP2B4 0.44 6.37 0.33 6e-10 Pancreatic cancer; LIHC cis rs4950322 0.600 rs11240014 chr1:146852395 G/A cg25205988 chr1:146714368 CHD1L -0.41 -5.95 -0.31 6.75e-9 Protein quantitative trait loci; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.58 0.56 4.49e-30 Prudent dietary pattern; LIHC cis rs7224737 1.000 rs1122326 chr17:40274873 A/C cg20291162 chr17:40259547 DHX58 -0.42 -6.17 -0.32 1.89e-9 Fibrinogen levels; LIHC cis rs6500602 0.634 rs2270365 chr16:4526758 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.72 0.3 2.27e-8 Schizophrenia; LIHC cis rs870825 0.616 rs7667449 chr4:185641711 T/C cg04058563 chr4:185651563 MLF1IP 0.77 7.78 0.39 8.45e-14 Blood protein levels; LIHC cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 12.11 0.55 2.49e-28 Platelet count; LIHC cis rs6684514 1.000 rs12038203 chr1:156248265 C/T cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs1862618 0.525 rs832403 chr5:56265992 G/T cg24531977 chr5:56204891 C5orf35 0.65 8.85 0.43 4.76e-17 Initial pursuit acceleration; LIHC cis rs694739 0.628 rs475032 chr11:64140737 G/C cg23796481 chr11:64053134 BAD;GPR137 -0.46 -6.23 -0.32 1.34e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7336332 0.662 rs9581862 chr13:28039993 T/G cg22138327 chr13:27999177 GTF3A 0.48 7.04 0.36 1.04e-11 Weight; LIHC cis rs4141404 0.828 rs2413043 chr22:31648576 G/T cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Paclitaxel-induced neuropathy; LIHC cis rs3806843 1.000 rs7710794 chr5:140209467 T/G cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.39e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg01570182 chr17:44337453 NA 0.93 9.49 0.46 3.97e-19 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4970988 0.640 rs7524734 chr1:150655686 C/T cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Urate levels; LIHC cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs2284553 0.516 rs2834208 chr21:34752763 G/T cg14850771 chr21:34775459 IFNGR2 -0.44 -6.9 -0.35 2.55e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg12463550 chr7:65579703 CRCP 0.67 7.18 0.36 4.48e-12 Diabetic kidney disease; LIHC trans rs11098499 0.909 rs10020034 chr4:120294331 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.64 0.42 2.27e-16 Corneal astigmatism; LIHC cis rs9309473 0.583 rs6713196 chr2:73576405 T/C cg20560298 chr2:73613845 ALMS1 -0.43 -6.82 -0.35 4.07e-11 Metabolite levels; LIHC cis rs1461503 0.868 rs7126785 chr11:122839564 C/A cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC trans rs900145 0.612 rs7114573 chr11:13323498 G/T cg01218619 chr4:25090298 NA 0.29 6.08 0.31 3.29e-9 Menarche (age at onset); LIHC cis rs7408868 1.000 rs1548554 chr19:15277938 C/T cg09752223 chr19:15281200 NOTCH3 -0.38 -5.99 -0.31 5.32e-9 Pulse pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26385779 chr5:150137906 DCTN4 0.43 6.3 0.32 9.3e-10 Cognitive function; LIHC cis rs4713118 0.513 rs149951 chr6:28033087 T/C cg16479474 chr6:28041457 NA 0.38 6.32 0.32 8.32e-10 Parkinson's disease; LIHC cis rs4820294 0.961 rs62236664 chr22:38059427 T/C cg00292662 chr22:38071168 LGALS1 0.64 10.06 0.48 4.92e-21 Fat distribution (HIV); LIHC cis rs4908768 0.906 rs55860300 chr1:8596335 G/A cg20416874 chr1:8611966 RERE 0.59 9.61 0.46 1.68e-19 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7772486 0.597 rs9386136 chr6:146158300 A/T cg23711669 chr6:146136114 FBXO30 0.63 9.63 0.46 1.44e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs950169 0.922 rs12911223 chr15:84831671 G/A cg12863693 chr15:85201151 NMB -0.4 -5.8 -0.3 1.47e-8 Schizophrenia; LIHC cis rs17826219 0.568 rs9907834 chr17:29154013 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.0 0.4 1.97e-14 Body mass index; LIHC cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg03517284 chr6:25882590 NA 0.48 6.07 0.31 3.39e-9 Intelligence (multi-trait analysis); LIHC cis rs4684776 0.867 rs7625184 chr3:11333734 C/T cg00170343 chr3:11313890 ATG7 0.49 6.9 0.35 2.59e-11 Small vessel stroke; LIHC cis rs1799949 0.965 rs9646413 chr17:41426157 A/G cg25072359 chr17:41440525 NA 0.39 6.13 0.31 2.49e-9 Menopause (age at onset); LIHC trans rs801193 1.000 rs2707850 chr7:66203870 G/T cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.89e-11 Aortic root size; LIHC trans rs2122469 0.793 rs76965656 chr8:20594376 A/G cg20211604 chr17:11632341 DNAH9 0.55 6.24 0.32 1.28e-9 Serum tamsulosin hydrochloride concentration; LIHC cis rs7826238 0.566 rs2945886 chr8:8148270 C/G cg14343924 chr8:8086146 FLJ10661 0.46 6.61 0.34 1.52e-10 Systolic blood pressure; LIHC cis rs76025697 1 rs76025697 chr5:179184488 G/A cg14593053 chr5:179126677 CANX 0.42 7.58 0.38 3.37e-13 Granulocyte percentage of myeloid white cells;Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Granulocyte count; LIHC cis rs8141529 0.719 rs5762825 chr22:29223642 A/G cg15103426 chr22:29168792 CCDC117 0.67 11.37 0.52 1.29e-25 Lymphocyte counts; LIHC cis rs912057 0.560 rs1294416 chr6:6741327 A/G cg06612196 chr6:6737390 NA 0.56 10.44 0.49 2.57e-22 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs919433 0.680 rs2605039 chr2:198362851 C/A cg03934865 chr2:198174659 NA 0.55 8.42 0.41 1.07e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs11098499 0.821 rs28665282 chr4:120384186 C/T cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs2404602 0.669 rs9788684 chr15:77194838 A/T cg03037974 chr15:76606532 NA 0.72 13.59 0.59 6.05e-34 Blood metabolite levels; LIHC cis rs10791097 0.967 rs6590512 chr11:130717916 A/G cg12179176 chr11:130786555 SNX19 -0.61 -9.36 -0.45 1.11e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7772486 0.790 rs2265469 chr6:146219049 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.89 -0.3 9.3e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9788682 0.947 rs7169584 chr15:78822660 A/T cg06917634 chr15:78832804 PSMA4 -0.51 -7.21 -0.36 3.67e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs4819052 0.851 rs2255774 chr21:46683851 A/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 8.15 0.4 6.98e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11122272 0.735 rs2486729 chr1:231535584 C/T cg06096015 chr1:231504339 EGLN1 0.48 8.98 0.44 1.89e-17 Hemoglobin concentration; LIHC cis rs7552404 0.924 rs7546641 chr1:76158035 T/C cg22875332 chr1:76189707 ACADM 0.48 7.45 0.37 7.7e-13 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2727020 0.553 rs3862350 chr11:49595912 A/C cg15704280 chr7:45808275 SEPT13 -0.99 -20.48 -0.74 2.03e-61 Coronary artery disease; LIHC cis rs2153535 0.542 rs4440510 chr6:8471818 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg10217327 chr6:118973057 C6orf204 0.69 7.04 0.36 1.03e-11 Diastolic blood pressure; LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.25 0.37 2.79e-12 Height; LIHC cis rs72781680 0.821 rs2176265 chr2:24158638 C/G cg08917208 chr2:24149416 ATAD2B 0.64 6.4 0.33 5.15e-10 Lymphocyte counts; LIHC cis rs763121 1.000 rs86796 chr22:38881454 A/C cg06022373 chr22:39101656 GTPBP1 -0.58 -10.77 -0.5 1.67e-23 Menopause (age at onset); LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg11062466 chr8:58055876 NA -0.56 -7.31 -0.37 1.86e-12 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg12311346 chr5:56204834 C5orf35 -0.56 -7.35 -0.37 1.45e-12 Initial pursuit acceleration; LIHC cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg23248424 chr5:179741104 GFPT2 -0.43 -6.44 -0.33 3.97e-10 Height; LIHC cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg13397359 chr6:42928475 GNMT 0.63 8.9 0.43 3.21e-17 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7191700 0.583 rs243314 chr16:11385104 G/C cg00044050 chr16:11439710 C16orf75 0.56 8.35 0.41 1.7e-15 Multiple sclerosis; LIHC cis rs2204008 0.775 rs11514369 chr12:38305411 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.19 0.4 5.23e-15 Bladder cancer; LIHC trans rs9641123 0.639 rs2677078 chr7:93257986 C/T cg09745688 chr16:2908918 PRSS22 -0.37 -6.4 -0.33 5.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs61990749 0.597 rs2267768 chr14:78216014 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.63 10.53 0.49 1.23e-22 Fibroblast growth factor basic levels; LIHC cis rs7106204 0.748 rs2403888 chr11:24208071 C/G ch.11.24196551F chr11:24239977 NA -0.76 -10.18 -0.48 2.03e-21 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4065321 0.522 rs11078930 chr17:38141955 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.76 14.86 0.63 6.84e-39 White blood cell count (basophil);White blood cell count; LIHC cis rs875971 0.862 rs10276077 chr7:65728411 A/G cg18252515 chr7:66147081 NA 0.45 6.46 0.33 3.62e-10 Aortic root size; LIHC cis rs13108904 0.604 rs11946375 chr4:1313488 T/C cg16405210 chr4:1374714 KIAA1530 -0.43 -6.36 -0.33 6.32e-10 Obesity-related traits; LIHC cis rs12291225 0.535 rs12806025 chr11:14413817 G/A cg19336497 chr11:14380999 RRAS2 -0.55 -10.37 -0.49 4.28e-22 Sense of smell; LIHC cis rs7223966 1.000 rs2013288 chr17:61785904 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.89 0.35 2.65e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4979906 0.920 rs11002239 chr10:79443836 A/C cg07817648 chr10:79422355 NA -0.32 -6.48 -0.33 3.21e-10 Mortality in heart failure; LIHC cis rs1799949 0.894 rs36062488 chr17:41337472 C/T cg05368731 chr17:41323189 NBR1 -0.67 -11.3 -0.52 2.18e-25 Menopause (age at onset); LIHC cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg05368731 chr17:41323189 NBR1 0.73 12.56 0.56 5.28e-30 Menopause (age at onset); LIHC trans rs4650994 0.544 rs2811306 chr1:178599248 C/G cg05059571 chr16:84539110 KIAA1609 0.41 6.96 0.35 1.73e-11 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7208859 0.623 rs73269923 chr17:29102571 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.18 0.4 5.73e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7666738 0.680 rs11726233 chr4:99079773 G/A cg05340658 chr4:99064831 C4orf37 0.69 12.35 0.56 3.22e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs12142240 0.730 rs56030283 chr1:46823093 C/G cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs7727544 0.660 rs274563 chr5:131717859 C/A cg24060327 chr5:131705240 SLC22A5 0.6 8.63 0.42 2.38e-16 Blood metabolite levels; LIHC cis rs919433 0.963 rs4850787 chr2:198181750 G/A cg03934865 chr2:198174659 NA -0.57 -9.33 -0.45 1.32e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs904251 0.504 rs2797795 chr6:37480683 T/C cg01843034 chr6:37503916 NA -0.48 -8.27 -0.41 3.1e-15 Cognitive performance; LIHC cis rs812925 0.502 rs2053750 chr2:61656273 T/A cg14146966 chr2:61757674 XPO1 -0.38 -6.19 -0.32 1.75e-9 Immature fraction of reticulocytes; LIHC cis rs4975709 0.569 rs2077269 chr5:1863506 C/T cg15595755 chr5:1867978 NA 0.41 8.25 0.41 3.45e-15 Cardiovascular disease risk factors; LIHC cis rs6960043 0.738 rs10950548 chr7:15057728 G/A cg19272540 chr7:15055459 NA 0.25 6.7 0.34 8.36e-11 Type 2 diabetes; LIHC cis rs4654899 0.758 rs6702331 chr1:21516107 A/T cg08539965 chr1:21396338 EIF4G3 0.33 5.84 0.3 1.22e-8 Superior frontal gyrus grey matter volume; LIHC cis rs1577917 0.771 rs2842612 chr6:86303091 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -12.01 -0.54 6.03e-28 Response to antipsychotic treatment; LIHC trans rs6489882 0.836 rs7967461 chr12:113369759 G/C cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs4713118 0.662 rs13218430 chr6:28029837 T/C cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs11711311 1.000 rs9826808 chr3:113455644 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.39 0.45 8.39e-19 IgG glycosylation; LIHC cis rs7552404 1.000 rs211718 chr1:76106675 C/T cg10523679 chr1:76189770 ACADM 0.59 8.25 0.41 3.55e-15 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7918232 0.941 rs1753415 chr10:27395102 T/C cg14240646 chr10:27532245 ACBD5 -0.69 -6.41 -0.33 4.77e-10 Breast cancer; LIHC cis rs4713118 0.955 rs9468201 chr6:27687035 C/T cg20933634 chr6:27740509 NA 0.48 6.42 0.33 4.64e-10 Parkinson's disease; LIHC cis rs3741404 0.825 rs11604782 chr11:63946650 G/A cg18225595 chr11:63971243 STIP1 0.68 10.58 0.5 8.26e-23 Platelet count; LIHC cis rs35146811 0.844 rs12705070 chr7:99656927 A/G cg13334819 chr7:99746414 C7orf59 -0.54 -7.85 -0.39 5.43e-14 Coronary artery disease; LIHC cis rs7712401 0.686 rs154511 chr5:122195554 T/A cg18764291 chr5:122110994 SNX2 0.33 5.76 0.3 1.89e-8 Mean platelet volume; LIHC cis rs4563143 0.663 rs2218396 chr19:29236392 C/T cg04546413 chr19:29218101 NA 0.39 7.51 0.38 5.03e-13 Methadone dose in opioid dependence; LIHC cis rs3812049 0.737 rs790154 chr5:127501235 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.46 5.74 0.3 2.14e-8 Lymphocyte counts;Red cell distribution width; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27543739 chr10:94334014 IDE 0.43 6.18 0.32 1.77e-9 Longevity; LIHC cis rs208515 0.525 rs4145045 chr6:66678949 T/C cg07460842 chr6:66804631 NA 0.76 8.85 0.43 4.72e-17 Exhaled nitric oxide levels; LIHC cis rs2717559 0.542 rs11774823 chr8:143887568 G/T cg07661805 chr8:143867942 LY6D -0.3 -6.56 -0.33 2e-10 Urinary tract infection frequency; LIHC trans rs12478296 0.901 rs59191623 chr2:243028595 G/A cg01596870 chr19:55963115 NA -0.66 -9.4 -0.45 8.25e-19 Obesity-related traits; LIHC cis rs1008375 1.000 rs7661631 chr4:17679751 T/C cg16339924 chr4:17578868 LAP3 -0.49 -6.47 -0.33 3.31e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7772486 0.782 rs7747576 chr6:146277827 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -5.77 -0.3 1.81e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs655641 1.000 rs527162 chr11:85715736 C/T cg09030501 chr11:85779252 PICALM -0.5 -5.95 -0.31 6.73e-9 Platelet count; LIHC cis rs1577917 1.000 rs12196411 chr6:86779762 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.03 -0.48 6.19e-21 Response to antipsychotic treatment; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06665941 chr21:34602869 IFNAR2 0.37 6.44 0.33 3.99e-10 Cognitive function; LIHC cis rs651907 0.557 rs35117343 chr3:101445126 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.4 0.52 9.54e-26 Colorectal cancer; LIHC cis rs5758511 0.596 rs55644935 chr22:42666069 A/G cg00645731 chr22:42541494 CYP2D7P1 0.52 8.25 0.41 3.41e-15 Birth weight; LIHC cis rs1008375 1.000 rs2872959 chr4:17677163 G/A cg02297831 chr4:17616191 MED28 -0.41 -5.74 -0.3 2.07e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs600806 0.850 rs4120621 chr1:109949008 A/G cg23091122 chr1:110024289 SYPL2 -0.45 -5.96 -0.31 6.44e-9 Intelligence (multi-trait analysis); LIHC cis rs1843834 0.898 rs4674936 chr2:225553731 C/T cg22455342 chr2:225449267 CUL3 0.45 6.17 0.32 1.95e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs5769765 1.000 rs5769764 chr22:50270784 G/A cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs10870270 0.956 rs67378218 chr10:133752420 A/C cg08754478 chr10:133766260 PPP2R2D -0.56 -8.25 -0.41 3.36e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7944735 0.506 rs10742816 chr11:47606984 C/T cg20307385 chr11:47447363 PSMC3 0.54 6.34 0.32 7.28e-10 Intraocular pressure; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg06873352 chr17:61820015 STRADA 0.73 13.06 0.58 6.74e-32 Prudent dietary pattern; LIHC cis rs7552404 0.690 rs12723575 chr1:76335203 T/C cg10523679 chr1:76189770 ACADM -0.55 -6.65 -0.34 1.17e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs13108904 0.934 rs13134106 chr4:1302902 A/G cg00684032 chr4:1343700 KIAA1530 0.54 7.86 0.39 5e-14 Obesity-related traits; LIHC cis rs1712517 0.771 rs7074749 chr10:105116056 C/T cg05636881 chr10:105038444 INA 0.49 7.59 0.38 3e-13 Migraine; LIHC trans rs800082 1.000 rs9882503 chr3:144321296 A/T cg24215973 chr2:240111563 HDAC4 -0.5 -7.44 -0.37 8.47e-13 Smoking behavior; LIHC cis rs7100689 0.577 rs10749551 chr10:82054001 A/C cg00277334 chr10:82204260 NA -0.55 -6.83 -0.35 3.86e-11 Post bronchodilator FEV1; LIHC cis rs2180341 0.920 rs4472373 chr6:127705983 G/A cg24812749 chr6:127587940 RNF146 1.06 16.01 0.65 1.89e-43 Breast cancer; LIHC cis rs6964587 1.000 rs2097739 chr7:91711466 C/T cg17063962 chr7:91808500 NA 1.01 19.29 0.72 1.22e-56 Breast cancer; LIHC cis rs4788570 0.545 rs8044144 chr16:71783121 T/C cg06353428 chr16:71660113 MARVELD3 1.36 14.64 0.62 5.27e-38 Intelligence (multi-trait analysis); LIHC cis rs651907 0.535 rs11714444 chr3:101513682 G/A cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs1843834 0.574 rs6436499 chr2:225456551 A/T cg22509189 chr2:225307070 NA -0.8 -11.15 -0.52 7.48e-25 IgE levels in asthmatics (D.p. specific); LIHC cis rs1215050 0.740 rs783949 chr4:99001933 A/G cg05340658 chr4:99064831 C4orf37 -0.4 -6.19 -0.32 1.74e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7551222 0.752 rs12138846 chr1:204556478 T/A cg20240347 chr1:204465584 NA -0.32 -6.58 -0.34 1.76e-10 Schizophrenia; LIHC cis rs1401999 0.898 rs4148564 chr3:183725982 C/T cg05044414 chr3:183734942 ABCC5 0.33 5.75 0.3 1.98e-8 Anterior chamber depth; LIHC cis rs459482 0.508 rs461093 chr21:42800190 C/G cg14166395 chr21:42792516 MX1 -0.46 -6.37 -0.33 5.95e-10 IgG glycosylation; LIHC cis rs10883723 0.810 rs2296589 chr10:104248106 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.08 0.58 5.66e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9649213 0.593 rs7458551 chr7:97952167 G/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs4979906 1.000 rs11002249 chr10:79447228 C/T cg07817648 chr10:79422355 NA -0.28 -6.23 -0.32 1.34e-9 Mortality in heart failure; LIHC cis rs12220238 1.000 rs12252705 chr10:75984863 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.76 0.34 5.8e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs763121 0.785 rs5750646 chr22:39013830 T/C cg21395723 chr22:39101663 GTPBP1 0.41 6.82 0.35 4.14e-11 Menopause (age at onset); LIHC cis rs4819052 0.851 rs9974628 chr21:46672647 C/T cg22633049 chr21:46681294 NA -0.36 -6.32 -0.32 8.25e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC cis rs360798 0.512 rs2215870 chr2:63132342 C/G cg17519650 chr2:63277830 OTX1 0.55 8.54 0.42 4.48e-16 Coronary artery disease; LIHC cis rs2279817 0.820 rs12754031 chr1:18006619 G/A cg21791023 chr1:18019539 ARHGEF10L -0.69 -7.84 -0.39 5.76e-14 Neuroticism; LIHC cis rs17253792 0.915 rs79894275 chr14:56180285 C/T cg01858014 chr14:56050164 KTN1 -0.75 -7.41 -0.37 9.7e-13 Putamen volume; LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg11766577 chr21:47581405 C21orf56 -0.46 -7.64 -0.38 2.18e-13 Testicular germ cell tumor; LIHC cis rs7249142 0.506 rs8101388 chr19:19293938 A/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.35 -5.95 -0.31 6.51e-9 IgG glycosylation; LIHC cis rs6546550 0.901 rs6546556 chr2:70139001 A/G cg02498382 chr2:70120550 SNRNP27 -0.44 -7.62 -0.38 2.56e-13 Prevalent atrial fibrillation; LIHC cis rs875971 0.545 rs4718364 chr7:66001340 C/A cg11764359 chr7:65958608 NA 0.61 8.83 0.43 5.48e-17 Aortic root size; LIHC cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg23262073 chr20:60523788 NA -0.29 -6.24 -0.32 1.33e-9 Body mass index; LIHC cis rs4243830 1.000 rs41278014 chr1:6579653 G/C cg22792644 chr1:6614718 TAS1R1;NOL9 0.84 8.58 0.42 3.43e-16 Body mass index; LIHC cis rs1336900 0.637 rs35967040 chr1:150555588 A/C cg15448220 chr1:150897856 SETDB1 -0.43 -6.45 -0.33 3.83e-10 Blood protein levels; LIHC cis rs78456975 0.527 rs11901028 chr2:1557972 A/G cg01028140 chr2:1542097 TPO -0.42 -6.56 -0.33 2.05e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs523522 1.000 rs523522 chr12:121020250 A/T cg12219531 chr12:120966889 COQ5 0.65 12.57 0.56 4.78e-30 High light scatter reticulocyte count; LIHC cis rs12586317 0.534 rs28384418 chr14:35452126 C/A cg16230307 chr14:35515116 FAM177A1 0.67 11.54 0.53 3.1e-26 Psoriasis; LIHC cis rs9942416 0.585 rs253407 chr5:74926778 A/G cg19683494 chr5:74908142 NA -0.47 -6.11 -0.31 2.74e-9 Age-related disease endophenotypes; LIHC cis rs12711979 0.765 rs6715805 chr2:3821117 T/C cg17052675 chr2:3827356 NA -0.42 -7.19 -0.36 4.16e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs11677370 0.561 rs4849990 chr2:3819558 A/G cg17052675 chr2:3827356 NA -0.5 -6.81 -0.35 4.42e-11 Type 2 diabetes; LIHC cis rs950169 0.922 rs12912934 chr15:85114447 C/T cg12863693 chr15:85201151 NMB 0.45 6.18 0.32 1.86e-9 Schizophrenia; LIHC cis rs644799 0.562 rs515546 chr11:95588756 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.65 10.57 0.5 8.43e-23 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs910316 1.000 rs10149880 chr14:75633008 A/G cg11812906 chr14:75593930 NEK9 -0.71 -13.86 -0.6 5.64e-35 Height; LIHC trans rs2404602 0.692 rs1867197 chr15:76910031 A/G cg18908981 chr3:43732200 ABHD5 0.46 6.73 0.34 6.96e-11 Blood metabolite levels; LIHC cis rs7903847 0.642 rs11189196 chr10:99155079 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2204008 0.774 rs3910796 chr12:38230660 G/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs7165170 0.549 rs11073935 chr15:91099638 A/G cg26821196 chr15:91095069 CRTC3 0.41 7.33 0.37 1.69e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs644148 0.679 rs2204119 chr19:44970975 T/C cg15540054 chr19:45004280 ZNF180 -0.78 -10.72 -0.5 2.66e-23 Personality dimensions; LIHC trans rs2243480 1.000 rs431076 chr7:65600320 A/C cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs910316 1.000 rs175425 chr14:75626131 T/C cg08847533 chr14:75593920 NEK9 -0.86 -17.71 -0.69 3.01e-50 Height; LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg20607798 chr8:58055168 NA 0.63 7.96 0.4 2.64e-14 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.11 0.31 2.79e-9 Menopause (age at onset); LIHC cis rs1451375 0.572 rs896309 chr7:50545022 A/G cg14593290 chr7:50529359 DDC -0.62 -10.12 -0.48 3.19e-21 Malaria; LIHC cis rs8017423 0.935 rs17260827 chr14:90732703 G/A cg14092571 chr14:90743983 NA 0.46 7.14 0.36 5.6e-12 Mortality in heart failure; LIHC cis rs941408 1.000 rs1736184 chr19:2810248 G/A cg06609049 chr19:2785107 THOP1 0.53 9.34 0.45 1.3e-18 Total cholesterol levels; LIHC cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs17428076 0.793 rs3770448 chr2:172692265 A/G cg13550731 chr2:172543902 DYNC1I2 0.38 6.11 0.31 2.74e-9 Myopia; LIHC cis rs1461503 0.900 rs7115852 chr11:122831830 G/A cg25161029 chr11:122845972 NA 0.41 6.7 0.34 8.41e-11 Menarche (age at onset); LIHC cis rs72781680 0.611 rs72781699 chr2:24277709 G/A cg06627628 chr2:24431161 ITSN2 -0.6 -6.95 -0.35 1.9e-11 Lymphocyte counts; LIHC cis rs7847628 0.587 rs3793638 chr9:123582697 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.97 19.64 0.73 5.11e-58 Birth weight; LIHC cis rs875971 0.638 rs10249404 chr7:66046724 G/A cg11764359 chr7:65958608 NA -0.72 -11.01 -0.51 2.52e-24 Aortic root size; LIHC cis rs1403694 1.000 rs1403694 chr3:186439998 T/C cg12454167 chr3:186435060 KNG1 0.29 7.17 0.36 4.62e-12 Blood protein levels; LIHC cis rs2108225 0.714 rs929393 chr7:107437048 C/T cg18560240 chr7:107437656 SLC26A3 -0.53 -8.61 -0.42 2.72e-16 Ulcerative colitis; LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg20607798 chr8:58055168 NA 0.63 7.96 0.4 2.62e-14 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.782 rs1454651 chr21:45012476 A/G cg21573476 chr21:45109991 RRP1B -0.5 -9.05 -0.44 1.08e-17 Mean corpuscular volume; LIHC cis rs17826219 0.706 rs609472 chr17:28951427 T/C cg13385521 chr17:29058706 SUZ12P 0.66 6.49 0.33 2.98e-10 Body mass index; LIHC cis rs11711311 0.784 rs13081931 chr3:113349928 G/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.31 -5.8 -0.3 1.5e-8 IgG glycosylation; LIHC cis rs2906856 0.848 rs3015001 chr12:68397373 C/G cg15249341 chr12:68405565 NA 0.34 6.88 0.35 2.82e-11 Mosquito bite size; LIHC trans rs35110281 0.776 rs9306159 chr21:45061839 G/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.22 0.32 1.49e-9 Mean corpuscular volume; LIHC cis rs2933343 0.533 rs11915889 chr3:128700866 A/C cg25356066 chr3:128598488 ACAD9 0.46 6.21 0.32 1.53e-9 IgG glycosylation; LIHC cis rs780096 0.546 rs2293572 chr2:27728777 C/G cg22903471 chr2:27725779 GCKR 0.52 9.03 0.44 1.31e-17 Total body bone mineral density; LIHC cis rs4824093 0.610 rs12106611 chr22:50242686 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -5.82 -0.3 1.35e-8 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs875971 0.638 rs10249404 chr7:66046724 G/A cg00343986 chr7:65444356 GUSB -0.38 -5.73 -0.3 2.17e-8 Aortic root size; LIHC cis rs8072100 0.846 rs4264433 chr17:45737275 A/T cg08085267 chr17:45401833 C17orf57 0.57 8.51 0.42 5.4e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs17401966 1.000 rs12141416 chr1:10327867 A/G cg19773385 chr1:10388646 KIF1B -0.4 -7.11 -0.36 6.8e-12 Hepatocellular carcinoma; LIHC trans rs1814175 0.616 rs847641 chr11:49919261 T/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs2576037 0.583 rs8086286 chr18:44467515 A/G cg19077165 chr18:44547161 KATNAL2 0.44 6.82 0.35 4.13e-11 Personality dimensions; LIHC cis rs7833986 0.501 rs2976044 chr8:56986737 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.69 7.38 0.37 1.23e-12 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg24927135 chr15:63449340 RPS27L -0.48 -6.2 -0.32 1.58e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs751728 1.000 rs1359781 chr6:33762104 T/C cg25922239 chr6:33757077 LEMD2 0.44 7.37 0.37 1.26e-12 Crohn's disease; LIHC cis rs3740540 0.507 rs897293 chr10:126290050 T/G cg04949429 chr10:126290192 LHPP 0.45 7.36 0.37 1.36e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs7091068 0.574 rs10748610 chr10:95462235 C/G cg20715218 chr10:95462985 C10orf4 0.6 6.56 0.33 1.94e-10 Urinary tract infection frequency; LIHC cis rs79839061 0.610 rs2279182 chr4:882625 T/G cg07828340 chr4:882639 GAK 0.85 7.64 0.38 2.25e-13 Intelligence (multi-trait analysis); LIHC cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg26818010 chr10:134567672 INPP5A -0.69 -8.89 -0.43 3.45e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.89 9.22 0.45 3.16e-18 Platelet count; LIHC cis rs644799 1.000 rs525404 chr11:95566520 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.71 0.67 3.15e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg00656387 chr3:40428638 ENTPD3 0.44 7.38 0.37 1.24e-12 Renal cell carcinoma; LIHC cis rs7927771 0.832 rs55677087 chr11:47397714 C/G cg20135002 chr11:47629003 NA -0.52 -8.81 -0.43 6.47e-17 Subjective well-being; LIHC cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs10878977 0.586 rs6581892 chr12:69817077 C/T cg17330252 chr12:69809627 NA -0.37 -5.8 -0.3 1.47e-8 Colorectal cancer; LIHC cis rs67460515 0.859 rs7610800 chr3:161002582 C/T cg03342759 chr3:160939853 NMD3 -0.66 -10.0 -0.48 7.89e-21 Parkinson's disease; LIHC cis rs7918232 0.505 rs788221 chr10:27442247 G/C cg14442939 chr10:27389572 ANKRD26 -0.71 -5.81 -0.3 1.46e-8 Breast cancer; LIHC trans rs1005277 0.579 rs9418322 chr10:38377296 G/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9916302 0.904 rs2338798 chr17:37547269 T/C cg00129232 chr17:37814104 STARD3 0.4 6.5 0.33 2.86e-10 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg00280220 chr17:61926910 NA 0.43 7.02 0.35 1.19e-11 Prudent dietary pattern; LIHC cis rs9303401 1.000 rs6503877 chr17:56841948 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.43 6.43 0.33 4.19e-10 Cognitive test performance; LIHC cis rs1816752 1.000 rs9511265 chr13:25012359 T/C cg02811702 chr13:24901961 NA 0.26 6.49 0.33 2.93e-10 Obesity-related traits; LIHC cis rs611744 0.967 rs682007 chr8:109210326 G/C cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs7534824 0.625 rs17610202 chr1:101429724 C/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.71 7.55 0.38 3.96e-13 Refractive astigmatism; LIHC cis rs7617773 0.780 rs35411187 chr3:48360017 C/G cg11946769 chr3:48343235 NME6 0.92 11.7 0.53 7.75e-27 Coronary artery disease; LIHC cis rs9457247 0.967 rs2769355 chr6:167380493 G/A cg12798992 chr6:167411361 FGFR1OP -0.6 -9.85 -0.47 2.62e-20 Crohn's disease; LIHC cis rs4423214 0.840 rs1792234 chr11:71182018 T/C cg05163923 chr11:71159392 DHCR7 -0.61 -8.1 -0.4 9.74e-15 Vitamin D levels; LIHC cis rs9868809 0.649 rs3733086 chr3:48699519 C/T cg07636037 chr3:49044803 WDR6 -0.64 -7.2 -0.36 3.93e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs921968 0.541 rs832798 chr2:219464810 G/A cg02985541 chr2:219472218 PLCD4 0.41 6.71 0.34 8.16e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs6088580 0.602 rs6059840 chr20:33030405 G/A cg08999081 chr20:33150536 PIGU 0.67 13.31 0.58 7.7e-33 Glomerular filtration rate (creatinine); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg18030105 chr11:3396237 ZNF195 0.41 6.13 0.31 2.49e-9 Immature fraction of reticulocytes; LIHC cis rs2354432 0.556 rs4295925 chr1:146857335 T/C cg25205988 chr1:146714368 CHD1L 0.84 9.52 0.46 3.35e-19 Mitochondrial DNA levels; LIHC cis rs9303280 0.806 rs4795399 chr17:38061439 T/C cg11212589 chr17:38028394 ZPBP2 0.36 7.3 0.37 2.05e-12 Self-reported allergy; LIHC cis rs7258465 0.931 rs271626 chr19:18627067 C/T cg10790698 chr19:18539756 SSBP4 0.34 7.05 0.36 1.03e-11 Breast cancer; LIHC cis rs8141529 0.719 rs9625619 chr22:29272328 T/A cg15103426 chr22:29168792 CCDC117 0.58 9.36 0.45 1.12e-18 Lymphocyte counts; LIHC cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.77 0.34 5.47e-11 Diabetic kidney disease; LIHC cis rs7647973 0.588 rs4855848 chr3:49653457 C/T cg03060546 chr3:49711283 APEH 0.59 6.78 0.34 5.41e-11 Menarche (age at onset); LIHC cis rs1023500 0.573 rs6002592 chr22:42476754 A/C cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.23 -0.32 1.35e-9 Schizophrenia; LIHC cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg06453172 chr10:134556979 INPP5A -0.64 -8.55 -0.42 4.14e-16 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7208859 0.673 rs9914271 chr17:29232625 G/A cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs72781680 0.611 rs72797824 chr2:24356456 T/G cg06627628 chr2:24431161 ITSN2 -0.62 -7.33 -0.37 1.64e-12 Lymphocyte counts; LIHC cis rs911119 0.779 rs3761280 chr20:23620076 A/G cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs8067354 0.609 rs1292066 chr17:57932314 T/A cg02344993 chr17:57696989 CLTC 0.68 11.01 0.51 2.42e-24 Hemoglobin concentration; LIHC cis rs644799 1.000 rs473148 chr11:95628606 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 15.91 0.65 4.75e-43 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs908922 0.676 rs11205018 chr1:152496249 T/G cg23254163 chr1:152506842 NA 0.23 5.86 0.3 1.11e-8 Hair morphology; LIHC cis rs67311347 1.000 rs10510708 chr3:40404770 A/G cg16822855 chr3:40428330 ENTPD3 0.33 6.13 0.31 2.46e-9 Renal cell carcinoma; LIHC cis rs1443512 0.812 rs2044210 chr12:54335533 C/G cg25024717 chr12:54324583 NA -0.3 -5.91 -0.3 8.5e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs763014 0.966 rs12935215 chr16:670605 T/C cg09263875 chr16:632152 PIGQ 0.61 10.64 0.5 4.85e-23 Height; LIHC cis rs1443512 0.812 rs1975472 chr12:54337083 A/G cg12374095 chr12:54320830 NA 0.4 5.81 0.3 1.42e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs67311347 0.577 rs1317217 chr3:40271697 T/G cg10755058 chr3:40428713 ENTPD3 0.36 5.95 0.31 6.71e-9 Renal cell carcinoma; LIHC cis rs9303401 0.703 rs9910629 chr17:57210301 C/G cg12560992 chr17:57184187 TRIM37 0.55 7.61 0.38 2.73e-13 Cognitive test performance; LIHC cis rs10464366 0.544 rs6952466 chr7:39155032 A/T cg20302533 chr7:39170763 POU6F2 0.39 7.24 0.36 2.89e-12 IgG glycosylation; LIHC cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.32 -5.9 -0.3 8.81e-9 Aortic root size; LIHC cis rs1075232 0.826 rs12437800 chr15:31671432 A/G cg01030201 chr15:31746330 NA -0.78 -6.11 -0.31 2.72e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs644799 0.582 rs473157 chr11:95596874 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.62 9.8 0.47 3.74e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1003719 0.788 rs2835592 chr21:38464387 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs12291225 0.585 rs4757250 chr11:14375683 C/A cg05501817 chr11:14380813 RRAS2 -0.44 -6.07 -0.31 3.46e-9 Sense of smell; LIHC cis rs6565681 0.760 rs9901680 chr17:78378088 A/G cg15383979 chr17:78362278 RNF213;LOC100294362 -0.55 -7.8 -0.39 7.74e-14 Moyamoya disease; LIHC cis rs6089829 0.889 rs6090206 chr20:61668363 G/A cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.74e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs1348850 0.958 rs11684320 chr2:178456346 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.78 11.89 0.54 1.54e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6089584 0.526 rs6089316 chr20:60627552 C/T cg06108461 chr20:60628389 TAF4 -0.65 -8.98 -0.44 1.87e-17 Body mass index; LIHC cis rs2303759 0.666 rs66967196 chr19:49808894 G/A cg22590775 chr19:49891494 CCDC155 0.46 7.33 0.37 1.65e-12 Multiple sclerosis; LIHC cis rs2073300 0.609 rs6137937 chr20:23385419 G/A cg16736954 chr20:23401023 NAPB 0.71 8.27 0.41 2.91e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg27297192 chr10:134578999 INPP5A 0.57 7.89 0.39 4.07e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg18230493 chr5:56204884 C5orf35 -0.44 -6.11 -0.31 2.74e-9 Initial pursuit acceleration; LIHC cis rs67981189 0.552 rs8021824 chr14:71537238 C/G cg15816911 chr14:71606274 NA 0.43 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs17685 0.623 rs7782808 chr7:75768645 C/T cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs600806 0.778 rs6693932 chr1:110003575 T/C cg23091122 chr1:110024289 SYPL2 -0.5 -6.38 -0.33 5.72e-10 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.915 rs1473553 chr12:122985057 G/T cg23029597 chr12:123009494 RSRC2 -0.54 -7.65 -0.38 2.1e-13 Body mass index; LIHC cis rs875971 0.862 rs801209 chr7:66019390 G/T cg11764359 chr7:65958608 NA -0.78 -13.63 -0.59 4.46e-34 Aortic root size; LIHC cis rs67478160 0.595 rs12879501 chr14:104272634 G/T cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs7633770 0.643 rs11130102 chr3:46689567 G/C cg11219411 chr3:46661640 NA -0.36 -6.02 -0.31 4.44e-9 Coronary artery disease; LIHC cis rs1865760 0.516 rs9393684 chr6:26075531 G/C cg17691542 chr6:26056736 HIST1H1C 0.43 6.14 0.31 2.35e-9 Height; LIHC cis rs9549367 0.713 rs510160 chr13:113822481 A/G cg00898013 chr13:113819073 PROZ 0.34 5.96 0.31 6.12e-9 Platelet distribution width; LIHC cis rs700651 0.786 rs58224025 chr2:198821988 G/A cg00792783 chr2:198669748 PLCL1 0.46 6.81 0.35 4.41e-11 Intracranial aneurysm; LIHC cis rs1983891 0.774 rs6935446 chr6:41514372 A/G cg20194872 chr6:41519635 FOXP4 0.41 6.47 0.33 3.39e-10 Prostate cancer; LIHC cis rs7617773 1.000 rs6442106 chr3:48190815 G/A cg11946769 chr3:48343235 NME6 -0.61 -8.14 -0.4 7.39e-15 Coronary artery disease; LIHC cis rs992157 0.764 rs2382827 chr2:219184387 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.15 0.48 2.48e-21 Colorectal cancer; LIHC cis rs10911232 0.520 rs10797831 chr1:183036816 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.58 0.5 8.27e-23 Hypertriglyceridemia; LIHC cis rs57221529 0.709 rs4957056 chr5:570105 T/C cg09021430 chr5:549028 NA -0.46 -9.02 -0.44 1.39e-17 Lung disease severity in cystic fibrosis; LIHC cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg11301795 chr4:187892539 NA -0.27 -7.11 -0.36 6.9e-12 Lobe attachment (rater-scored or self-reported); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg19262334 chr18:74631861 ZNF236 0.46 6.05 0.31 3.89e-9 Hepatitis; LIHC cis rs2239547 0.522 rs2336162 chr3:52951519 C/T cg11645453 chr3:52864694 ITIH4 -0.32 -8.01 -0.4 1.81e-14 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24272902 chr3:178867151 PIK3CA -0.52 -6.13 -0.31 2.43e-9 Systolic blood pressure; LIHC cis rs12477438 0.798 rs1530996 chr2:99584079 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.79 -10.4 -0.49 3.54e-22 Chronic sinus infection; LIHC cis rs782590 0.774 rs782629 chr2:55900283 C/T cg03859395 chr2:55845619 SMEK2 -0.76 -12.8 -0.57 6.53e-31 Metabolic syndrome; LIHC cis rs17253792 0.822 rs75115817 chr14:56069537 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs1707322 0.890 rs2297883 chr1:46511487 G/C cg06784218 chr1:46089804 CCDC17 -0.36 -6.58 -0.34 1.81e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs875971 0.545 rs2460427 chr7:65619205 T/C cg26939375 chr7:64535504 NA -0.4 -6.37 -0.33 5.94e-10 Aortic root size; LIHC cis rs798554 0.660 rs2644295 chr7:2860217 A/C cg13628971 chr7:2884303 GNA12 0.41 6.57 0.33 1.88e-10 Height; LIHC cis rs9309473 1.000 rs1881245 chr2:73649928 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.66 -0.34 1.12e-10 Metabolite levels; LIHC cis rs4689592 0.503 rs11945642 chr4:7051065 G/C cg06697600 chr4:7070879 GRPEL1 0.6 9.19 0.45 3.84e-18 Monocyte percentage of white cells; LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs10479542 0.892 rs7736163 chr5:178980316 G/C cg19723775 chr5:179050963 HNRNPH1 0.38 5.93 0.31 7.25e-9 Lung cancer; LIHC cis rs2204008 0.639 rs7311462 chr12:38278130 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs7412746 0.524 rs58304714 chr1:150831561 T/A cg15448220 chr1:150897856 SETDB1 0.39 5.77 0.3 1.77e-8 Melanoma; LIHC cis rs798554 0.679 rs2644300 chr7:2883071 G/A cg04166393 chr7:2884313 GNA12 0.52 8.21 0.41 4.53e-15 Height; LIHC cis rs67311347 1.000 rs9848083 chr3:40466979 A/G cg24209194 chr3:40518798 ZNF619 -0.43 -6.31 -0.32 8.76e-10 Renal cell carcinoma; LIHC cis rs2153535 0.580 rs9406169 chr6:8509470 A/T cg07606381 chr6:8435919 SLC35B3 0.79 12.25 0.55 7.15e-29 Motion sickness; LIHC cis rs548181 0.611 rs609200 chr11:125383808 G/A cg03464685 chr11:125439445 EI24 -1.51 -15.27 -0.64 1.73e-40 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7592578 0.882 rs16832765 chr2:191468762 T/C cg10560079 chr2:191398806 TMEM194B -0.88 -12.23 -0.55 8.81e-29 Diastolic blood pressure; LIHC trans rs3749237 0.964 rs62260719 chr3:49852419 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.61 9.0 0.44 1.55e-17 Resting heart rate; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg11060661 chr22:24314208 DDT;DDTL -0.48 -7.04 -0.36 1.07e-11 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs6545883 0.860 rs777589 chr2:61425621 T/C cg14146966 chr2:61757674 XPO1 0.44 7.22 0.36 3.34e-12 Tuberculosis; LIHC trans rs11098499 0.575 rs907204 chr4:120238654 G/A cg25214090 chr10:38739885 LOC399744 0.53 8.54 0.42 4.49e-16 Corneal astigmatism; LIHC cis rs2404602 0.632 rs34338978 chr15:77226805 T/C cg03037974 chr15:76606532 NA 0.72 13.97 0.6 2.11e-35 Blood metabolite levels; LIHC cis rs7027203 0.797 rs7870672 chr9:96606693 A/C cg13679303 chr9:96623674 NA -0.3 -6.65 -0.34 1.15e-10 DNA methylation (variation); LIHC cis rs13126513 0.708 rs1057613 chr4:100504985 G/A cg05468953 chr4:100565104 NA 0.32 6.05 0.31 3.76e-9 Metabolite levels (MHPG); LIHC trans rs9388451 0.839 rs3799711 chr6:126075313 C/T cg05039488 chr6:79577232 IRAK1BP1 0.51 8.08 0.4 1.16e-14 Brugada syndrome; LIHC cis rs1577917 1.000 rs11758849 chr6:86708262 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.84 -0.35 3.71e-11 Response to antipsychotic treatment; LIHC cis rs875971 0.862 rs778736 chr7:65813848 C/T cg18252515 chr7:66147081 NA -0.46 -6.86 -0.35 3.33e-11 Aortic root size; LIHC cis rs722599 0.715 rs8008785 chr14:75307600 G/A cg08847533 chr14:75593920 NEK9 -0.51 -7.81 -0.39 6.84e-14 IgG glycosylation; LIHC cis rs7757419 1.000 rs7773610 chr6:34435180 C/A cg17518776 chr6:34434842 PACSIN1 -0.3 -6.1 -0.31 2.86e-9 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals; LIHC cis rs17818399 0.926 rs13032670 chr2:46830794 C/T cg02822958 chr2:46747628 ATP6V1E2 0.45 6.74 0.34 6.72e-11 Height; LIHC cis rs611744 0.870 rs613179 chr8:109166006 G/A cg18478394 chr8:109455254 TTC35 0.39 6.66 0.34 1.1e-10 Dupuytren's disease; LIHC cis rs11229555 0.645 rs11229443 chr11:58197188 G/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2075371 0.674 rs11771785 chr7:134013249 A/G cg20476274 chr7:133979776 SLC35B4 -0.49 -6.64 -0.34 1.21e-10 Mean platelet volume; LIHC cis rs11997175 0.603 rs716584 chr8:33779748 C/G ch.8.33884649F chr8:33765107 NA 0.37 6.42 0.33 4.61e-10 Body mass index; LIHC cis rs9457247 0.967 rs2757054 chr6:167380501 A/G cg12798992 chr6:167411361 FGFR1OP -0.6 -9.85 -0.47 2.62e-20 Crohn's disease; LIHC cis rs8081395 0.707 rs1024637 chr17:58038893 C/T cg02344993 chr17:57696989 CLTC -0.35 -5.73 -0.3 2.23e-8 White blood cell count; LIHC cis rs427394 0.802 rs274694 chr5:6734079 A/G cg10857441 chr5:6722123 POLS -0.37 -6.38 -0.33 5.79e-10 Menopause (age at onset); LIHC cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 9.92 0.47 1.54e-20 Platelet count; LIHC cis rs11696739 0.583 rs2243602 chr20:1546742 T/A cg15722679 chr20:1638393 SIRPG -0.37 -7.29 -0.37 2.12e-12 Mean platelet volume; LIHC cis rs9583531 0.527 rs2391866 chr13:111363294 A/T cg24331049 chr13:111365604 ING1 0.78 13.12 0.58 3.85e-32 Coronary artery disease; LIHC cis rs11761441 0.602 rs6963983 chr7:93176 A/C cg25149888 chr7:81075 NA -0.26 -5.73 -0.3 2.25e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs2070488 0.965 rs13079145 chr3:38517992 T/G cg24069376 chr3:38537580 EXOG 0.43 7.85 0.39 5.24e-14 Electrocardiographic conduction measures; LIHC cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.11 -0.36 7.03e-12 Diabetic kidney disease; LIHC cis rs1059312 0.966 rs12370194 chr12:129277250 A/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.71 -13.55 -0.59 8.72e-34 Systemic lupus erythematosus; LIHC cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg09323728 chr8:95962352 TP53INP1 -0.34 -7.52 -0.38 4.97e-13 Type 2 diabetes; LIHC cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg11301795 chr4:187892539 NA -0.26 -6.99 -0.35 1.44e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs61931739 0.500 rs11053248 chr12:34518011 G/A cg26384229 chr12:38710491 ALG10B 0.79 9.79 0.47 4.2e-20 Morning vs. evening chronotype; LIHC trans rs2243480 0.706 rs6460257 chr7:65196780 C/T cg10756647 chr7:56101905 PSPH 1.12 17.16 0.68 4.55e-48 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06136555 chr12:112123888 ACAD10;BRAP 0.46 6.54 0.33 2.18e-10 Lung function (FEV1/FVC); LIHC cis rs17253792 0.822 rs17253716 chr14:56153661 G/C cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC cis rs2073300 0.609 rs6137951 chr20:23429459 T/C cg12062639 chr20:23401060 NAPB 0.99 12.64 0.56 2.51e-30 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11098499 0.909 rs2127821 chr4:120394535 T/C cg09307838 chr4:120376055 NA 0.77 12.33 0.55 3.85e-29 Corneal astigmatism; LIHC cis rs11190604 0.943 rs2495744 chr10:102329409 C/T cg07080220 chr10:102295463 HIF1AN 0.56 7.81 0.39 7.19e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg11861562 chr11:117069780 TAGLN 0.49 8.12 0.4 8.82e-15 Blood protein levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg14392066 chr9:130497359 TOR2A -0.4 -6.06 -0.31 3.53e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs9296095 0.796 rs3846855 chr6:33555877 G/A cg14003231 chr6:33640908 ITPR3 0.33 6.12 0.31 2.53e-9 Platelet count; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.59 0.62 7.89e-38 Prudent dietary pattern; LIHC cis rs6062302 0.522 rs2282157 chr20:62227180 C/G cg06363034 chr20:62225388 GMEB2 -0.45 -7.6 -0.38 2.8e-13 Glioblastoma; LIHC cis rs9399137 0.507 rs12663810 chr6:135289782 G/C cg24558204 chr6:135376177 HBS1L 0.62 10.55 0.5 1e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs8180040 0.966 rs9683177 chr3:47490493 G/A cg27129171 chr3:47204927 SETD2 0.56 9.57 0.46 2.3e-19 Colorectal cancer; LIHC cis rs4808199 0.895 rs7252888 chr19:19628037 C/T cg03709012 chr19:19516395 GATAD2A 1.07 18.89 0.71 4.96e-55 Nonalcoholic fatty liver disease; LIHC cis rs2607426 0.681 rs10420651 chr19:41235038 C/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.52 -6.2 -0.32 1.67e-9 Blood protein levels; LIHC cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg19318889 chr4:1322082 MAEA 0.46 7.62 0.38 2.57e-13 Obesity-related traits; LIHC cis rs4478037 0.822 rs9817393 chr3:33117069 A/G cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.01 -0.35 1.32e-11 Major depressive disorder; LIHC cis rs2274273 0.967 rs10137409 chr14:55611441 A/C cg01864836 chr14:55583639 NA -0.36 -6.12 -0.31 2.62e-9 Protein biomarker; LIHC trans rs9528384 0.927 rs9645947 chr13:62229100 A/G cg20705804 chr7:43590176 HECW1 0.55 6.1 0.31 2.82e-9 Verbal declarative memory; LIHC cis rs17401966 1.000 rs58053556 chr1:10442903 A/G cg15208524 chr1:10270712 KIF1B 0.43 5.8 0.3 1.53e-8 Hepatocellular carcinoma; LIHC trans rs11039798 0.588 rs11039807 chr11:48549391 T/A cg15704280 chr7:45808275 SEPT13 0.56 6.21 0.32 1.57e-9 Axial length; LIHC cis rs7953508 0.711 rs11611927 chr12:93977591 A/G cg18151635 chr12:93972918 NA -0.48 -7.55 -0.38 3.87e-13 Pubertal anthropometrics; LIHC cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg10802521 chr3:52805072 NEK4 -0.43 -7.14 -0.36 5.58e-12 Bipolar disorder; LIHC trans rs13113518 0.812 rs12500686 chr4:56324089 A/G cg15358633 chr12:38710606 ALG10B 0.43 6.09 0.31 2.99e-9 Height; LIHC cis rs2439831 0.850 rs56909447 chr15:44137618 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.33 0.41 2.02e-15 Lung cancer in ever smokers; LIHC cis rs7103648 0.808 rs7103835 chr11:47461693 G/A cg20307385 chr11:47447363 PSMC3 0.91 13.17 0.58 2.45e-32 Diastolic blood pressure;Systolic blood pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg10118784 chr14:65209977 PLEKHG3 -0.39 -6.04 -0.31 4.08e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.862 rs6978028 chr7:65886300 G/C cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC cis rs11971779 0.553 rs10085770 chr7:139100349 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs10193935 1.000 rs10171023 chr2:42407093 G/C cg27598129 chr2:42591480 NA -0.75 -11.21 -0.52 4.72e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs7592578 0.639 rs61709084 chr2:191287685 A/C cg10560079 chr2:191398806 TMEM194B -0.78 -11.26 -0.52 3.07e-25 Diastolic blood pressure; LIHC cis rs6788895 1.000 rs1879420 chr3:150466564 A/G cg09723797 chr3:150481914 SIAH2 0.76 9.89 0.47 1.83e-20 Breast cancer; LIHC cis rs7103648 0.966 rs11500477 chr11:47409051 T/A cg20307385 chr11:47447363 PSMC3 0.99 16.78 0.67 1.51e-46 Diastolic blood pressure;Systolic blood pressure; LIHC trans rs875971 0.545 rs1065265 chr7:65841203 C/T cg26939375 chr7:64535504 NA 0.4 6.29 0.32 9.67e-10 Aortic root size; LIHC cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg18230493 chr5:56204884 C5orf35 -0.43 -6.03 -0.31 4.26e-9 Initial pursuit acceleration; LIHC cis rs9399135 0.967 rs4637662 chr6:135298158 T/C cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.37e-11 Red blood cell count; LIHC cis rs5769765 0.908 rs9616216 chr22:50318927 T/C cg26441486 chr22:50317300 CRELD2 0.39 6.59 0.34 1.65e-10 Schizophrenia; LIHC cis rs2629540 0.855 rs12776722 chr10:126469833 G/A cg20435097 chr10:126320824 FAM53B -0.45 -6.35 -0.32 6.75e-10 Cocaine dependence; LIHC cis rs2115536 1.000 rs2903105 chr15:80189523 C/G cg00225070 chr15:80189496 MTHFS 0.66 11.21 0.52 4.84e-25 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs7927592 0.956 rs7126340 chr11:68257293 C/T cg16797656 chr11:68205561 LRP5 0.54 8.54 0.42 4.59e-16 Total body bone mineral density; LIHC cis rs62064224 0.560 rs12162135 chr17:30805795 A/C cg25809561 chr17:30822961 MYO1D 0.35 6.11 0.31 2.73e-9 Schizophrenia; LIHC cis rs7309 0.810 rs11684253 chr2:162034536 G/T cg21211367 chr2:162094118 NA 0.37 5.73 0.3 2.25e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs1419980 0.673 rs1978284 chr12:7771151 G/A cg25828445 chr12:7781288 NA 0.44 6.85 0.35 3.39e-11 HDL cholesterol levels; LIHC cis rs2425143 1.000 rs2425143 chr20:34350666 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -7.06 -0.36 9.17e-12 Blood protein levels; LIHC cis rs911119 0.657 rs13039144 chr20:23633755 A/G cg16589663 chr20:23618590 CST3 0.66 6.47 0.33 3.47e-10 Chronic kidney disease; LIHC cis rs17401966 0.928 rs11121531 chr1:10277357 G/A cg15208524 chr1:10270712 KIF1B 0.44 6.37 0.33 6e-10 Hepatocellular carcinoma; LIHC cis rs7618501 1.000 rs11130219 chr3:49752427 C/T cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07628178 chr2:157442412 GPD2 0.39 6.41 0.33 4.9e-10 Longevity; LIHC cis rs7208859 0.673 rs11650305 chr17:29229361 A/C cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs743757 1.000 rs2236957 chr3:50440426 A/G cg05260129 chr3:50388622 TUSC4;CYB561D2 0.47 6.74 0.34 6.8e-11 Diastolic blood pressure; LIHC cis rs752010 0.871 rs2038976 chr1:42094498 A/G cg06885757 chr1:42089581 HIVEP3 0.29 5.91 0.3 8.49e-9 Lupus nephritis in systemic lupus erythematosus; LIHC trans rs3780486 0.801 rs10971424 chr9:33138775 T/C cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs2412488 0.720 rs28459503 chr4:54310058 C/A cg22241045 chr4:54363911 LNX1 -0.41 -6.58 -0.34 1.72e-10 DNA methylation (variation); LIHC cis rs17826219 0.706 rs55764512 chr17:29085758 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.21 0.41 4.55e-15 Body mass index; LIHC cis rs7312933 0.567 rs11181399 chr12:42666412 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.83 0.39 6.29e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.54 -10.05 -0.48 5.32e-21 Total body bone mineral density; LIHC cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg18230493 chr5:56204884 C5orf35 -0.44 -6.14 -0.32 2.31e-9 Type 2 diabetes; LIHC cis rs941408 1.000 rs1640272 chr19:2800192 A/T cg06609049 chr19:2785107 THOP1 0.53 9.34 0.45 1.23e-18 Total cholesterol levels; LIHC cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg10802521 chr3:52805072 NEK4 -0.45 -7.59 -0.38 3.16e-13 Electroencephalogram traits; LIHC cis rs898097 0.841 rs2271918 chr17:80861206 A/G cg15369054 chr17:80825471 TBCD 0.43 6.26 0.32 1.15e-9 Breast cancer; LIHC cis rs778371 0.522 rs10205801 chr2:233597196 G/A cg25237894 chr2:233734115 C2orf82 0.35 6.43 0.33 4.23e-10 Schizophrenia; LIHC cis rs9486719 1.000 rs2499804 chr6:96861216 A/G cg06623918 chr6:96969491 KIAA0776 0.71 7.01 0.35 1.28e-11 Migraine;Coronary artery disease; LIHC trans rs66573146 0.572 rs66734745 chr4:6948765 T/C cg07817883 chr1:32538562 TMEM39B 1.02 9.01 0.44 1.54e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs9640161 0.750 rs73170185 chr7:150030191 C/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.55 -9.11 -0.44 7.04e-18 Blood protein levels;Circulating chemerin levels; LIHC trans rs1005277 0.579 rs2983343 chr10:38383332 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs919433 0.679 rs1598469 chr2:198515658 T/C cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.46e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4746818 1.000 rs10762263 chr10:70970178 A/G cg11621586 chr10:70884670 VPS26A 0.84 12.94 0.57 1.92e-31 Left atrial antero-posterior diameter; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg12419862 chr22:24373484 LOC391322 0.7 10.96 0.51 3.8e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9303401 0.538 rs8078280 chr17:56473132 A/G cg25039879 chr17:56429692 SUPT4H1 0.76 8.71 0.43 1.35e-16 Cognitive test performance; LIHC cis rs11630290 0.589 rs12324851 chr15:64163495 G/A cg12036633 chr15:63758958 NA 0.57 6.21 0.32 1.55e-9 Iris characteristics; LIHC cis rs11958404 0.546 rs10475647 chr5:157443489 A/G cg05962755 chr5:157440814 NA 0.62 8.19 0.41 5.09e-15 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26398333 chr1:153895721 GATAD2B 0.41 6.35 0.32 6.75e-10 Cognitive function; LIHC trans rs11088226 1.000 rs11701627 chr21:33927794 T/A cg09050820 chr6:167586206 TCP10L2 0.78 12.09 0.55 2.98e-28 Gastritis; LIHC cis rs11122272 0.735 rs11122279 chr1:231519804 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.17 -0.48 2.11e-21 Hemoglobin concentration; LIHC cis rs7727544 0.901 rs55633655 chr5:131598756 T/G cg24060327 chr5:131705240 SLC22A5 -0.51 -5.81 -0.3 1.4e-8 Blood metabolite levels; LIHC cis rs8062405 0.964 rs7187333 chr16:28865916 G/A cg07451762 chr16:28383216 NA 0.33 6.13 0.31 2.44e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs1005277 0.579 rs2474595 chr10:38426782 C/G cg17830980 chr10:43048298 ZNF37B 0.55 11.26 0.52 3.12e-25 Extrinsic epigenetic age acceleration; LIHC cis rs7044106 0.762 rs1324473 chr9:123404610 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.68 -11.01 -0.51 2.54e-24 Hip circumference adjusted for BMI; LIHC cis rs7552404 0.924 rs1694419 chr1:76219801 C/T cg10523679 chr1:76189770 ACADM 0.64 9.61 0.46 1.58e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11822910 1.000 rs4477456 chr11:57197781 G/A cg00522883 chr11:57194120 SLC43A3 0.71 8.61 0.42 2.74e-16 Platelet distribution width; LIHC cis rs950169 0.840 rs4842854 chr15:84942339 T/G cg03959625 chr15:84868606 LOC388152 0.47 6.68 0.34 9.94e-11 Schizophrenia; LIHC cis rs3020736 0.500 rs2839708 chr22:42500745 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7520050 0.931 rs11576305 chr1:46460046 C/T cg03146154 chr1:46216737 IPP -0.38 -6.27 -0.32 1.11e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 6.22 0.32 1.43e-9 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00480142 chr12:96046743 NA -0.4 -6.68 -0.34 9.55e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs9486719 0.690 rs2092094 chr6:96844123 G/C cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs8141529 0.956 rs469989 chr22:29303595 G/C cg02153584 chr22:29168773 CCDC117 -0.41 -6.23 -0.32 1.37e-9 Lymphocyte counts; LIHC cis rs7572733 0.576 rs4850441 chr2:198913413 A/G cg10820045 chr2:198174542 NA -0.4 -5.87 -0.3 1.01e-8 Dermatomyositis; LIHC cis rs1003719 0.762 rs8130846 chr21:38480242 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.76 0.54 4.62e-27 Eye color traits; LIHC cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.73 -0.3 2.25e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1949733 0.701 rs940134 chr4:8454870 C/T cg11789530 chr4:8429930 ACOX3 0.76 11.0 0.51 2.74e-24 Response to antineoplastic agents; LIHC trans rs9650315 0.866 rs34495936 chr8:57196273 A/G cg22946562 chr2:1880012 MYT1L 0.36 6.07 0.31 3.37e-9 Height; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg01411255 chr17:61851458 DDX42;CCDC47 1.01 22.18 0.77 3.52e-68 Height; LIHC cis rs3008870 0.755 rs2815360 chr1:67494458 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.65 11.09 0.51 1.23e-24 Lymphocyte percentage of white cells; LIHC trans rs7246657 0.943 rs7255785 chr19:37971683 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.24e-10 Coronary artery calcification; LIHC cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg19318889 chr4:1322082 MAEA 0.48 6.71 0.34 7.86e-11 Obesity-related traits; LIHC cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 6.2 0.32 1.62e-9 Electroencephalogram traits; LIHC cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg18404041 chr3:52824283 ITIH1 -0.57 -9.17 -0.44 4.56e-18 Bipolar disorder; LIHC cis rs8180040 1.000 rs295458 chr3:47385585 C/A cg02527881 chr3:46936655 PTH1R -0.31 -6.08 -0.31 3.25e-9 Colorectal cancer; LIHC cis rs72653721 0.793 rs9468122 chr6:10965925 T/C cg13562911 chr6:11044106 ELOVL2 0.49 7.02 0.35 1.24e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs9517302 0.512 rs9517305 chr13:99097910 G/C cg22223119 chr13:99095684 FARP1 -0.64 -9.99 -0.48 8.59e-21 Obesity-related traits; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09656405 chr15:69745057 RPLP1 0.39 6.39 0.33 5.34e-10 Cognitive function; LIHC cis rs8062405 1.000 rs4788099 chr16:28855727 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs244293 0.965 rs2787504 chr17:53178341 A/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.54 0.38 4.36e-13 Menarche (age at onset); LIHC cis rs911119 0.913 rs6106685 chr20:23581612 A/C cg16589663 chr20:23618590 CST3 0.67 7.15 0.36 5.25e-12 Chronic kidney disease; LIHC cis rs6582630 0.555 rs12372536 chr12:38400864 C/G cg26384229 chr12:38710491 ALG10B 0.6 8.26 0.41 3.15e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs2336384 1.000 rs4846083 chr1:12045555 G/T cg13216073 chr1:12042593 MFN2 0.38 5.81 0.3 1.47e-8 Platelet count; LIHC cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg15691649 chr6:25882328 NA -0.52 -6.66 -0.34 1.1e-10 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.628 rs309811 chr2:136625602 A/G cg07305463 chr2:136567211 LCT 0.39 7.61 0.38 2.7e-13 Mosquito bite size; LIHC cis rs3008870 0.792 rs72673729 chr1:67441673 T/TG cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.32 -0.66 1.07e-44 Lymphocyte percentage of white cells; LIHC cis rs933688 0.536 rs332537 chr5:90794973 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 -0.73 -10.72 -0.5 2.65e-23 Smoking behavior; LIHC cis rs10911251 0.508 rs2245784 chr1:183107665 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.55 0.5 1.07e-22 Colorectal cancer; LIHC trans rs1941687 0.526 rs9959347 chr18:31316169 C/T cg27147174 chr7:100797783 AP1S1 -0.46 -7.03 -0.36 1.15e-11 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs12765878 1.000 rs34300861 chr10:105643332 A/C cg11005552 chr10:105648138 OBFC1 0.39 6.15 0.32 2.2e-9 Coronary artery disease; LIHC cis rs17102423 0.594 rs1256417 chr14:65563678 C/T cg16583315 chr14:65563665 MAX -0.38 -7.87 -0.39 4.86e-14 Obesity-related traits; LIHC cis rs11229555 0.645 rs7947248 chr11:58197750 C/T cg15696309 chr11:58395628 NA -0.65 -7.67 -0.38 1.76e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6964587 0.933 rs13230837 chr7:91779017 A/G cg17063962 chr7:91808500 NA 1.03 20.21 0.74 2.58e-60 Breast cancer; LIHC cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg05665937 chr4:1216051 CTBP1 0.39 6.19 0.32 1.7e-9 Obesity-related traits; LIHC cis rs3731896 0.700 rs11903211 chr2:220193434 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.56 6.52 0.33 2.58e-10 Educational attainment; LIHC cis rs11786130 1.000 rs10808565 chr8:129007412 C/T cg01765152 chr8:129005526 PVT1 -0.3 -6.39 -0.33 5.32e-10 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs2834188 1.000 rs9982088 chr21:34686841 A/G cg14352951 chr21:34696688 IFNAR1 0.49 6.73 0.34 7.17e-11 Narcolepsy; LIHC cis rs7617773 0.744 rs2125482 chr3:48323133 T/G cg11946769 chr3:48343235 NME6 0.88 11.21 0.52 4.85e-25 Coronary artery disease; LIHC cis rs3008870 0.755 rs2815380 chr1:67510857 A/G cg02640540 chr1:67518911 SLC35D1 -0.66 -12.98 -0.57 1.32e-31 Lymphocyte percentage of white cells; LIHC cis rs7078219 0.505 rs11190140 chr10:101291593 T/C cg06854084 chr10:101292507 NKX2-3 -0.33 -6.08 -0.31 3.14e-9 Dental caries; LIHC cis rs9814567 0.806 rs4074521 chr3:134325536 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.59 9.43 0.45 6.32e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs9929218 0.954 rs9646284 chr16:68791306 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.6 -9.28 -0.45 1.98e-18 Colorectal cancer; LIHC cis rs262150 0.567 rs2527177 chr7:158804737 T/C cg19418458 chr7:158789849 NA -0.41 -6.76 -0.34 5.94e-11 Facial morphology (factor 20); LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg02711726 chr17:80685570 FN3KRP -0.42 -7.79 -0.39 7.89e-14 Glycated hemoglobin levels; LIHC cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg08888203 chr3:10149979 C3orf24 0.53 6.43 0.33 4.35e-10 Alzheimer's disease; LIHC cis rs8062405 0.755 rs12445823 chr16:28588049 A/C cg07451762 chr16:28383216 NA 0.39 6.88 0.35 2.88e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7762018 1.000 rs60253563 chr6:170083019 T/C cg13891659 chr6:170190454 C6orf122;C6orf208 0.51 5.91 0.3 8.08e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9549367 0.789 rs9549365 chr13:113907391 C/T cg18105134 chr13:113819100 PROZ 0.56 9.9 0.47 1.74e-20 Platelet distribution width; LIHC cis rs477692 0.870 rs532248 chr10:131414156 T/A cg05714579 chr10:131428358 MGMT 0.48 8.07 0.4 1.18e-14 Response to temozolomide; LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg00656387 chr3:40428638 ENTPD3 0.48 8.05 0.4 1.36e-14 Renal cell carcinoma; LIHC cis rs1577917 0.958 rs12215232 chr6:86785430 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.33 -0.37 1.67e-12 Response to antipsychotic treatment; LIHC cis rs16854884 0.586 rs4561830 chr3:143735572 C/T cg06585982 chr3:143692056 C3orf58 0.58 7.5 0.38 5.47e-13 Economic and political preferences (feminism/equality); LIHC cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg15691649 chr6:25882328 NA -0.84 -11.13 -0.52 9.14e-25 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg02187348 chr16:89574699 SPG7 0.61 9.67 0.46 1.05e-19 Multiple myeloma (IgH translocation); LIHC cis rs9325144 0.600 rs7312522 chr12:38730423 A/G cg26384229 chr12:38710491 ALG10B 0.59 8.28 0.41 2.77e-15 Morning vs. evening chronotype; LIHC trans rs6058796 0.892 rs35103329 chr20:31238139 G/A cg02600331 chr11:130417168 NA 0.38 7.5 0.38 5.53e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.23e-9 Menopause (age at onset); LIHC cis rs908922 0.676 rs545418 chr1:152497338 C/T cg20991723 chr1:152506922 NA 0.59 10.49 0.49 1.6400000000000001e-22 Hair morphology; LIHC cis rs611744 0.819 rs424012 chr8:109154652 A/G cg21045802 chr8:109455806 TTC35 0.46 7.52 0.38 4.86e-13 Dupuytren's disease; LIHC cis rs2370759 0.945 rs74625866 chr10:32597618 A/T cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg27432699 chr2:27873401 GPN1 -0.54 -7.82 -0.39 6.6e-14 Total body bone mineral density; LIHC cis rs6598955 0.724 rs12726972 chr1:26639634 A/G cg00852783 chr1:26633632 UBXN11 -0.45 -7.35 -0.37 1.49e-12 Obesity-related traits; LIHC cis rs9303401 0.614 rs12950028 chr17:56510140 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.89 11.94 0.54 1.05e-27 Cognitive test performance; LIHC cis rs8103278 1.000 rs7258283 chr19:46335511 C/T cg11657440 chr19:46296263 DMWD -0.54 -8.37 -0.41 1.48e-15 Coronary artery disease; LIHC cis rs10927875 0.632 rs2862162 chr1:16142960 A/C cg21385522 chr1:16154831 NA 1.06 16.87 0.67 6.8e-47 Dilated cardiomyopathy; LIHC cis rs9611565 0.559 rs5758397 chr22:42019251 C/T cg06634786 chr22:41940651 POLR3H 0.71 7.38 0.37 1.23e-12 Vitiligo; LIHC trans rs8030605 0.704 rs72740592 chr15:56652811 A/T cg01710580 chr16:598674 SOLH -0.66 -6.07 -0.31 3.41e-9 Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17384381 0.861 rs35240561 chr1:85775217 C/G cg16011679 chr1:85725395 C1orf52 0.92 9.64 0.46 1.28e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs4820294 1.000 rs713835 chr22:38064650 C/T cg00292662 chr22:38071168 LGALS1 0.64 10.15 0.48 2.48e-21 Fat distribution (HIV); LIHC cis rs9457247 0.566 rs10946207 chr6:167456036 C/T cg12798992 chr6:167411361 FGFR1OP 0.48 7.06 0.36 9.47e-12 Crohn's disease; LIHC cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg11890956 chr21:40555474 PSMG1 -0.9 -12.01 -0.54 5.83e-28 Cognitive function; LIHC cis rs6835098 0.962 rs6851632 chr4:174109611 A/G cg27433088 chr4:174089019 GALNT7 0.41 6.95 0.35 1.86e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs694739 1.000 rs646153 chr11:64089588 C/T cg02228329 chr11:64053129 BAD;GPR137 0.75 10.77 0.5 1.68e-23 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs2629540 0.847 rs10901807 chr10:126384610 G/A cg08799069 chr10:126477246 METTL10 0.47 7.4 0.37 1.07e-12 Cocaine dependence; LIHC cis rs16828019 0.929 rs11209734 chr1:41698074 C/T cg03387723 chr1:41708464 SCMH1 -0.44 -7.23 -0.36 3.16e-12 Intelligence (multi-trait analysis); LIHC cis rs2637030 0.586 rs1552649 chr5:52870476 A/T cg06476337 chr5:52856530 NDUFS4 0.42 6.59 0.34 1.7e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs11971779 0.715 rs7781459 chr7:139093882 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.21 0.48 1.55e-21 Diisocyanate-induced asthma; LIHC cis rs2637266 0.626 rs2583066 chr10:78555839 T/C cg18941641 chr10:78392320 NA 0.3 6.46 0.33 3.58e-10 Pulmonary function; LIHC cis rs778371 1.000 rs778370 chr2:233743363 C/T cg08000102 chr2:233561755 GIGYF2 -0.85 -13.54 -0.59 9.49e-34 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg27055842 chr21:33765028 C21orf119;URB1 -0.55 -6.25 -0.32 1.24e-9 Systolic blood pressure; LIHC cis rs6701037 0.681 rs1057239 chr1:175130204 G/A cg00958927 chr1:175162553 KIAA0040 -0.39 -6.5 -0.33 2.83e-10 Alcohol dependence; LIHC cis rs9649465 1.000 rs11765478 chr7:123362872 A/C cg03229431 chr7:123269106 ASB15 -0.38 -8.06 -0.4 1.25e-14 Migraine; LIHC cis rs6461049 0.638 rs1859993 chr7:2183702 A/G cg14004847 chr7:1930337 MAD1L1 -0.4 -5.91 -0.3 8.19e-9 Schizophrenia; LIHC cis rs7326068 0.524 rs9506531 chr13:21232983 C/T cg27234864 chr13:21295941 IL17D -0.38 -5.89 -0.3 9.48e-9 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs9790314 0.905 rs6789388 chr3:160970437 G/A cg03342759 chr3:160939853 NMD3 -0.74 -9.61 -0.46 1.59e-19 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01002995 chr12:8185077 FOXJ2 -0.45 -6.41 -0.33 4.85e-10 Pancreatic cancer; LIHC cis rs7085104 0.572 rs284858 chr10:104573936 T/C cg15744005 chr10:104629667 AS3MT 0.37 7.88 0.39 4.39e-14 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs10493773 0.674 rs414618 chr1:86220418 G/A cg17807903 chr1:86174739 ZNHIT6 0.49 9.18 0.44 4.31e-18 Urate levels in overweight individuals; LIHC cis rs7124681 0.528 rs74608150 chr11:47696214 A/T cg20307385 chr11:47447363 PSMC3 0.74 11.17 0.52 6.36e-25 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs2710642 0.821 rs56373728 chr2:63095792 G/A cg17519650 chr2:63277830 OTX1 0.57 8.73 0.43 1.17e-16 LDL cholesterol levels;LDL cholesterol; LIHC cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg16405210 chr4:1374714 KIAA1530 -0.53 -7.79 -0.39 8.36e-14 Longevity; LIHC cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs8180040 0.726 rs1869871 chr3:47023948 C/T cg02527881 chr3:46936655 PTH1R -0.31 -6.09 -0.31 3.06e-9 Colorectal cancer; LIHC cis rs9640161 0.750 rs3800780 chr7:150027284 C/A cg17279839 chr7:150038598 RARRES2 0.56 11.38 0.52 1.13e-25 Blood protein levels;Circulating chemerin levels; LIHC cis rs7512552 0.839 rs11577843 chr1:150398258 A/G cg15654264 chr1:150340011 RPRD2 0.69 11.23 0.52 4.11e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg25894440 chr7:65020034 NA -0.51 -5.85 -0.3 1.13e-8 Diabetic kidney disease; LIHC cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg02034447 chr16:89574710 SPG7 0.49 7.39 0.37 1.14e-12 Multiple myeloma (IgH translocation); LIHC trans rs10506458 1.000 rs73127086 chr12:63415626 G/A cg22491629 chr6:157744540 C6orf35 -0.6 -10.91 -0.51 5.62e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.39 -5.94 -0.31 6.89e-9 Prudent dietary pattern; LIHC cis rs7945705 0.869 rs7925728 chr11:9013002 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -7.47 -0.37 6.74e-13 Hemoglobin concentration; LIHC cis rs908922 0.676 rs491077 chr1:152519570 C/A cg20991723 chr1:152506922 NA 0.54 9.0 0.44 1.57e-17 Hair morphology; LIHC trans rs1728785 1.000 rs4783657 chr16:68586322 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.2 0.32 1.64e-9 Ulcerative colitis; LIHC cis rs4319547 0.661 rs7398014 chr12:122943980 T/C cg23029597 chr12:123009494 RSRC2 -0.53 -7.47 -0.37 6.66e-13 Body mass index; LIHC cis rs798554 0.797 rs1182183 chr7:2873136 C/T cg13628971 chr7:2884303 GNA12 0.52 7.33 0.37 1.71e-12 Height; LIHC cis rs7772486 0.790 rs2265917 chr6:146212285 A/G cg23711669 chr6:146136114 FBXO30 0.63 11.04 0.51 1.88e-24 Lobe attachment (rater-scored or self-reported); LIHC trans rs9858542 1.000 rs9823546 chr3:49705512 T/A cg21659725 chr3:3221576 CRBN -0.54 -6.11 -0.31 2.65e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs60871478 0.679 rs6962050 chr7:817201 A/G cg05535760 chr7:792225 HEATR2 0.97 12.98 0.57 1.38e-31 Cerebrospinal P-tau181p levels; LIHC cis rs2153535 0.580 rs9406174 chr6:8516764 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.77 0.54 4.4e-27 Motion sickness; LIHC cis rs5758659 0.633 rs762995 chr22:42672124 A/G cg19513890 chr22:42538836 CYP2D7P1 -0.31 -5.93 -0.31 7.24e-9 Cognitive function; LIHC cis rs7193541 0.640 rs4072222 chr16:74706736 A/C cg01733217 chr16:74700730 RFWD3 0.95 22.69 0.78 3.56e-70 Multiple myeloma; LIHC cis rs35883536 1.000 rs11586051 chr1:101096240 A/T cg14515779 chr1:101123966 NA 0.63 12.39 0.56 2.3e-29 Monocyte count; LIHC cis rs950776 0.531 rs12915652 chr15:78831928 G/A cg06917634 chr15:78832804 PSMA4 0.95 14.37 0.61 5.73e-37 Sudden cardiac arrest; LIHC cis rs6754311 0.509 rs12616520 chr2:136516748 A/T cg25344623 chr2:136566232 LCT 0.41 7.63 0.38 2.31e-13 Mosquito bite size; LIHC cis rs7772486 0.806 rs2253648 chr6:146199296 G/A cg23711669 chr6:146136114 FBXO30 0.6 11.05 0.51 1.78e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs7909074 0.966 rs4948645 chr10:45391481 A/G cg05187965 chr10:45406764 TMEM72 -0.28 -7.05 -0.36 1.02e-11 Mean corpuscular volume; LIHC trans rs9951602 0.512 rs9955812 chr18:76650954 T/A cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC cis rs4243830 1.000 rs12027598 chr1:6600804 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 0.87 9.1 0.44 7.73e-18 Body mass index; LIHC trans rs10506458 0.915 rs998505 chr12:63400018 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.73 -10.4 -0.49 3.54e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs2243480 1.000 rs1618893 chr7:66096119 C/T cg18252515 chr7:66147081 NA -1.08 -14.52 -0.62 1.57e-37 Diabetic kidney disease; LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg22561889 chr6:118971681 C6orf204 0.55 5.79 0.3 1.6e-8 Diastolic blood pressure; LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg21448741 chr8:58168803 NA 0.38 6.83 0.35 3.84e-11 Developmental language disorder (linguistic errors); LIHC cis rs10876993 0.928 rs1689592 chr12:58057773 C/T cg18357645 chr12:58087776 OS9 0.51 8.43 0.41 9.66e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs13064411 0.696 rs6808394 chr3:113122524 T/G cg18753928 chr3:113234510 CCDC52 -0.42 -5.74 -0.3 2.05e-8 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg00343986 chr7:65444356 GUSB 0.44 6.11 0.31 2.74e-9 Aortic root size; LIHC cis rs4474465 0.850 rs10793324 chr11:78251485 C/T cg27205649 chr11:78285834 NARS2 -0.42 -6.46 -0.33 3.51e-10 Alzheimer's disease (survival time); LIHC cis rs1862618 0.671 rs2591956 chr5:56244604 G/A cg12311346 chr5:56204834 C5orf35 0.44 5.99 0.31 5.44e-9 Initial pursuit acceleration; LIHC cis rs4555082 0.874 rs2142190 chr14:105719306 G/A cg06808227 chr14:105710500 BRF1 -0.49 -6.05 -0.31 3.79e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs6088580 0.524 rs6088575 chr20:33273403 C/T cg08999081 chr20:33150536 PIGU 0.5 8.68 0.42 1.61e-16 Glomerular filtration rate (creatinine); LIHC cis rs3857067 0.806 rs9996975 chr4:95101338 C/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.79 -0.39 8.19e-14 QT interval; LIHC cis rs3768617 0.510 rs4651142 chr1:183097386 A/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.57e-22 Fuchs's corneal dystrophy; LIHC cis rs10752881 0.809 rs3768613 chr1:183106296 G/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.33 0.49 6.11e-22 Colorectal cancer; LIHC cis rs6545883 0.894 rs2593633 chr2:61571513 T/C cg15711740 chr2:61764176 XPO1 0.42 5.82 0.3 1.32e-8 Tuberculosis; LIHC cis rs8058578 0.887 rs28421305 chr16:30838128 G/A cg02466173 chr16:30829666 NA -0.47 -7.56 -0.38 3.83e-13 Multiple myeloma; LIHC cis rs7098414 0.511 rs7907575 chr10:82152675 T/G cg00277334 chr10:82204260 NA -0.61 -10.07 -0.48 4.66e-21 Post bronchodilator FEV1; LIHC cis rs6920965 0.561 rs9401851 chr6:126181956 T/C cg05901451 chr6:126070800 HEY2 -0.36 -6.19 -0.32 1.75e-9 High light scatter reticulocyte count; LIHC cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.55 8.83 0.43 5.38e-17 Schizophrenia; LIHC cis rs11098499 0.954 rs28685688 chr4:120420334 T/C cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC cis rs74181299 0.684 rs1420184 chr2:65315880 G/C cg05010058 chr2:65284262 CEP68 -0.4 -6.66 -0.34 1.13e-10 Pulse pressure; LIHC cis rs6674176 0.569 rs34830883 chr1:44405339 T/C cg12908607 chr1:44402522 ARTN -0.51 -8.81 -0.43 6.18e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11190604 1.000 rs7100386 chr10:102301417 C/T cg07080220 chr10:102295463 HIF1AN 0.52 7.23 0.36 3.13e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs875971 1.000 rs4718307 chr7:65610988 A/G cg11764359 chr7:65958608 NA -0.88 -15.36 -0.64 7.22e-41 Aortic root size; LIHC cis rs116095464 0.558 rs10052012 chr5:231908 T/C cg22857025 chr5:266934 NA -1.48 -17.96 -0.7 2.77e-51 Breast cancer; LIHC cis rs2439831 0.867 rs2251844 chr15:43836478 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.69 11.02 0.51 2.24e-24 Lung cancer in ever smokers; LIHC cis rs10078 0.571 rs2721014 chr5:463539 G/A cg08916839 chr5:415575 AHRR 0.6 12.58 0.56 4.31e-30 Fat distribution (HIV); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02369015 chr19:2702924 GNG7 -0.53 -6.14 -0.32 2.31e-9 Systolic blood pressure; LIHC cis rs17376456 0.877 rs55832164 chr5:93436579 C/T cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs7927592 0.913 rs12284933 chr11:68319489 G/A cg01657329 chr11:68192670 LRP5 -0.47 -6.15 -0.32 2.22e-9 Total body bone mineral density; LIHC cis rs3859192 0.599 rs34342173 chr17:38161507 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.91 0.65 4.82e-43 White blood cell count; LIHC cis rs60871478 1.000 rs4374882 chr7:821798 C/T cg05535760 chr7:792225 HEATR2 0.76 10.77 0.5 1.79e-23 Cerebrospinal P-tau181p levels; LIHC cis rs992157 0.730 rs2891078 chr2:219184432 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.15 0.48 2.48e-21 Colorectal cancer; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg14988396 chr8:25316392 CDCA2;KCTD9 -0.55 -6.49 -0.33 3.06e-10 Preeclampsia; LIHC cis rs5769765 0.913 rs2319462 chr22:50263370 C/T cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs2108622 1.000 rs2108622 chr19:15990431 C/T cg13772218 chr19:15982569 NA 0.39 8.34 0.41 1.85e-15 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs4242434 0.892 rs11776549 chr8:22493124 C/T cg03733263 chr8:22462867 KIAA1967 0.83 11.75 0.54 5.44e-27 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg22963979 chr7:1858916 MAD1L1 -0.37 -5.88 -0.3 9.77e-9 Bipolar disorder and schizophrenia; LIHC cis rs801193 1.000 rs2707850 chr7:66203870 G/T cg14393609 chr7:65229607 NA 0.37 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs3096299 0.606 rs4785674 chr16:89536613 A/G cg06640241 chr16:89574553 SPG7 0.61 8.97 0.44 1.95e-17 Multiple myeloma (IgH translocation); LIHC cis rs1198430 0.714 rs946265 chr1:23775296 T/G cg13183780 chr1:23809682 ASAP3 -0.38 -6.44 -0.33 4.03e-10 Total cholesterol levels; LIHC cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg21724239 chr8:58056113 NA 0.57 7.02 0.35 1.22e-11 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg03264133 chr6:25882463 NA -0.62 -8.73 -0.43 1.12e-16 Blood metabolite levels; LIHC trans rs208520 0.690 rs12201156 chr6:66720874 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.75 8.66 0.42 1.83e-16 Exhaled nitric oxide output; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg23752198 chr20:30311963 BCL2L1 -0.45 -6.15 -0.32 2.18e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2933343 1.000 rs789213 chr3:128616359 C/G cg25356066 chr3:128598488 ACAD9 -0.54 -7.14 -0.36 5.75e-12 IgG glycosylation; LIHC cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg02034447 chr16:89574710 SPG7 0.46 7.17 0.36 4.54e-12 Multiple myeloma (IgH translocation); LIHC trans rs7731783 1 rs7731783 chr5:177060312 T/C cg17398003 chr5:175665565 C5orf25 -0.37 -6.13 -0.31 2.47e-9 Methadone dose in opioid dependence; LIHC cis rs2758596 1.000 rs2758617 chr1:156160693 A/G cg24450063 chr1:156163899 SLC25A44 0.96 10.36 0.49 4.51e-22 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs9309711 0.666 rs11127429 chr2:3485224 T/G cg10845886 chr2:3471009 TTC15 -0.43 -8.16 -0.4 6.67e-15 Neurofibrillary tangles; LIHC cis rs10464366 0.544 rs34866559 chr7:39166071 G/A cg15212455 chr7:39170539 POU6F2 0.48 8.49 0.42 6.22e-16 IgG glycosylation; LIHC cis rs921968 0.643 rs537520 chr2:219381852 A/G cg18887096 chr2:219472410 PLCD4 0.36 6.53 0.33 2.35e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6424115 0.931 rs2473377 chr1:24148260 T/C cg10978503 chr1:24200527 CNR2 0.38 9.08 0.44 9.05e-18 Immature fraction of reticulocytes; LIHC cis rs57221529 0.709 rs72706611 chr5:561146 C/A cg09021430 chr5:549028 NA -0.45 -9.09 -0.44 8.22e-18 Lung disease severity in cystic fibrosis; LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg21448741 chr8:58168803 NA 0.37 5.97 0.31 5.98e-9 Developmental language disorder (linguistic errors); LIHC cis rs939574 0.720 rs6714820 chr2:220071803 C/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.96 -10.46 -0.49 2.05e-22 Platelet distribution width; LIHC cis rs8060686 0.641 rs73612690 chr16:68153200 G/A cg05110241 chr16:68378359 PRMT7 -0.57 -6.64 -0.34 1.27e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg23221052 chr5:179740743 GFPT2 -0.41 -5.86 -0.3 1.11e-8 Height; LIHC trans rs3812049 0.784 rs6889311 chr5:127431285 A/G cg16011800 chr17:1958478 HIC1 -0.52 -7.42 -0.37 9.6e-13 Lymphocyte counts;Red cell distribution width; LIHC cis rs2072499 0.868 rs2758600 chr1:156195205 C/T cg24450063 chr1:156163899 SLC25A44 1.02 16.75 0.67 2.13e-46 Testicular germ cell tumor; LIHC cis rs875971 0.965 rs7794930 chr7:65778546 A/C cg18252515 chr7:66147081 NA 0.42 5.93 0.31 7.46e-9 Aortic root size; LIHC cis rs8180040 0.620 rs9845728 chr3:47103376 C/T cg16586182 chr3:47516702 SCAP -0.49 -8.78 -0.43 7.8e-17 Colorectal cancer; LIHC cis rs10276381 0.786 rs10272155 chr7:28246989 A/G cg23620719 chr7:28220237 JAZF1 0.6 7.68 0.38 1.66e-13 Crohn's disease; LIHC cis rs4727027 0.870 rs62507485 chr7:148764182 C/T cg23583168 chr7:148888333 NA -0.66 -9.04 -0.44 1.19e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg22618164 chr12:122356400 WDR66 0.55 9.33 0.45 1.35e-18 Mean corpuscular volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19504496 chr19:36119917 RBM42 0.47 7.19 0.36 4.17e-12 Cognitive function; LIHC cis rs748404 0.690 rs2244981 chr15:43752751 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.35 0.37 1.44e-12 Lung cancer; LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg02782426 chr3:40428986 ENTPD3 0.33 6.14 0.32 2.31e-9 Renal cell carcinoma; LIHC cis rs9322817 0.607 rs9404572 chr6:105149439 T/C cg02098413 chr6:105308735 HACE1 -0.41 -8.06 -0.4 1.33e-14 Thyroid stimulating hormone; LIHC cis rs8072100 0.840 rs12452796 chr17:45479733 G/T cg08085267 chr17:45401833 C17orf57 0.55 8.24 0.41 3.6e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs11122272 0.735 rs2808596 chr1:231530723 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.43 -0.49 2.67e-22 Hemoglobin concentration; LIHC cis rs240764 0.658 rs846803 chr6:101272801 C/T cg09795085 chr6:101329169 ASCC3 -0.55 -7.79 -0.39 8.24e-14 Neuroticism; LIHC cis rs6964587 1.000 rs11982047 chr7:91705274 G/A cg17063962 chr7:91808500 NA 1.02 19.51 0.73 1.6e-57 Breast cancer; LIHC cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg06453172 chr10:134556979 INPP5A -0.63 -8.32 -0.41 2.11e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7618501 0.633 rs2883057 chr3:49998282 C/T cg24110177 chr3:50126178 RBM5 -0.48 -7.71 -0.38 1.35e-13 Intelligence (multi-trait analysis); LIHC cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg21280719 chr6:42927975 GNMT -0.31 -6.93 -0.35 2.13e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9625935 0.518 rs245008 chr22:30315736 T/C cg01021169 chr22:30184971 ASCC2 -0.35 -6.14 -0.32 2.31e-9 Tonsillectomy; LIHC cis rs9303401 0.659 rs62081315 chr17:56781468 T/C cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg08132940 chr7:1081526 C7orf50 -0.78 -6.48 -0.33 3.25e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6542838 0.704 rs56125264 chr2:99516699 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.41 -6.7 -0.34 8.49e-11 Fear of minor pain; LIHC cis rs1018836 0.828 rs7816023 chr8:91567398 T/C cg16814680 chr8:91681699 NA -0.54 -8.44 -0.42 9.02e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs765787 0.530 rs11070451 chr15:45533541 T/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg11062466 chr8:58055876 NA 0.5 7.14 0.36 5.49e-12 Developmental language disorder (linguistic errors); LIHC cis rs7769051 0.614 rs6912936 chr6:133102664 A/G cg07930552 chr6:133119739 C6orf192 0.71 6.85 0.35 3.46e-11 Type 2 diabetes nephropathy; LIHC cis rs11098499 0.779 rs7674500 chr4:120303593 C/T cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg13395646 chr4:1353034 KIAA1530 -0.43 -6.14 -0.32 2.31e-9 Longevity; LIHC cis rs10876993 0.890 rs2619441 chr12:58083015 C/A cg18357645 chr12:58087776 OS9 0.53 8.61 0.42 2.63e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs244293 0.965 rs2787487 chr17:53209382 G/C cg19360675 chr17:53046073 COX11;STXBP4 -0.46 -6.64 -0.34 1.21e-10 Menarche (age at onset); LIHC cis rs8180040 0.966 rs12636851 chr3:47463567 C/T cg16586182 chr3:47516702 SCAP -0.6 -11.81 -0.54 3.2e-27 Colorectal cancer; LIHC cis rs3008870 0.755 rs2815362 chr1:67496803 C/T cg02640540 chr1:67518911 SLC35D1 0.45 6.99 0.35 1.42e-11 Lymphocyte percentage of white cells; LIHC cis rs2834188 1.000 rs13050445 chr21:34703597 C/T cg04842828 chr21:34696676 IFNAR1 -0.49 -6.32 -0.32 7.97e-10 Narcolepsy; LIHC cis rs3809566 1.000 rs3809566 chr15:63333724 A/G cg12160578 chr15:63334699 TPM1 -0.61 -8.78 -0.43 8.01e-17 Platelet count; LIHC cis rs4638749 0.734 rs4676191 chr2:108861242 A/G cg25838818 chr2:108905173 SULT1C2 -0.39 -6.99 -0.35 1.47e-11 Blood pressure; LIHC cis rs12477438 0.520 rs13798 chr2:99813614 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.88 13.1 0.58 4.56e-32 Chronic sinus infection; LIHC cis rs1552244 0.882 rs2030564 chr3:10039044 A/G cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs7927592 0.871 rs11228284 chr11:68322767 A/T cg01657329 chr11:68192670 LRP5 -0.47 -6.15 -0.32 2.22e-9 Total body bone mineral density; LIHC cis rs17125944 0.506 rs7151491 chr14:53313711 C/G cg00686598 chr14:53173677 PSMC6 -0.84 -9.92 -0.47 1.47e-20 Alzheimer's disease (late onset); LIHC cis rs950776 0.714 rs514743 chr15:78884227 A/T cg06917634 chr15:78832804 PSMA4 -0.61 -8.36 -0.41 1.64e-15 Sudden cardiac arrest; LIHC cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs12079745 0.793 rs12073439 chr1:169284482 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.66 -6.3 -0.32 9.31e-10 QT interval; LIHC cis rs7020830 0.858 rs7856690 chr9:37127545 A/T cg14294708 chr9:37120828 ZCCHC7 1.04 21.51 0.76 1.59e-65 Schizophrenia; LIHC cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg16606324 chr3:10149918 C3orf24 0.54 5.9 0.3 8.94e-9 Alzheimer's disease; LIHC cis rs1434579 0.864 rs12978167 chr19:44942628 T/C cg15540054 chr19:45004280 ZNF180 0.57 7.97 0.4 2.39e-14 Tuberculosis; LIHC cis rs9296092 0.538 rs9461879 chr6:33516907 C/T cg13560919 chr6:33536144 NA -0.39 -6.29 -0.32 9.47e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs932541 1.000 rs6111152 chr20:16456088 A/G cg17003395 chr20:16555519 KIF16B 0.42 5.78 0.3 1.65e-8 Intelligence; LIHC cis rs4689642 0.709 rs35194996 chr4:7226477 G/C cg21353189 chr4:7228343 SORCS2 0.37 6.19 0.32 1.71e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs10197940 0.624 rs6724796 chr2:152412813 C/T cg19508488 chr2:152266495 RIF1 0.63 9.33 0.45 1.33e-18 Lung cancer; LIHC cis rs3753275 0.690 rs6577490 chr1:8549133 G/A cg20416874 chr1:8611966 RERE -0.47 -5.73 -0.3 2.25e-8 Educational attainment; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg10064575 chr17:40610771 ATP6V0A1 0.45 6.08 0.31 3.17e-9 Glycated hemoglobin levels; LIHC cis rs7582180 0.629 rs11685250 chr2:100955137 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.54 0.42 4.39e-16 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg22528358 chr1:107598549 PRMT6 0.71 11.63 0.53 1.43e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12971120 0.891 rs2278159 chr18:72178161 T/C cg26446133 chr18:72167187 CNDP2 -0.79 -14.23 -0.61 2e-36 Refractive error; LIHC cis rs5758511 0.680 rs34107327 chr22:42648353 T/G cg00645731 chr22:42541494 CYP2D7P1 0.53 8.59 0.42 3.1e-16 Birth weight; LIHC cis rs1577917 0.804 rs2786854 chr6:86668740 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.2 -0.36 3.82e-12 Response to antipsychotic treatment; LIHC cis rs6963495 0.818 rs114865717 chr7:105158526 C/T cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg23640757 chr6:7889014 TXNDC5 0.51 6.37 0.33 5.95e-10 Lung function (FEV1); LIHC cis rs7945705 0.935 rs1883098 chr11:8890594 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -9.17 -0.44 4.58e-18 Hemoglobin concentration; LIHC cis rs34779708 0.966 rs17591781 chr10:35498538 G/A cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.5e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6723226 0.708 rs2710627 chr2:32758627 A/G cg02381751 chr2:32503542 YIPF4 0.73 11.03 0.51 2.06e-24 Intelligence (multi-trait analysis); LIHC cis rs3750965 0.919 rs12280942 chr11:68859683 A/G cg06818126 chr11:68850279 TPCN2 0.43 7.16 0.36 4.89e-12 Hair color; LIHC cis rs4407350 0.721 rs131157 chr22:44891722 A/G cg26276947 chr22:44892394 LDOC1L 0.32 6.1 0.31 2.87e-9 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.898 rs72782126 chr2:24039901 A/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs9381040 0.701 rs722442 chr6:41089681 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.38 -6.14 -0.31 2.34e-9 Alzheimer's disease (late onset); LIHC cis rs599083 0.530 rs667126 chr11:68177728 C/T cg16797656 chr11:68205561 LRP5 -0.48 -7.49 -0.38 5.78e-13 Bone mineral density (spine); LIHC trans rs637571 0.544 rs12361552 chr11:65701204 G/A cg17712092 chr4:129076599 LARP1B -0.76 -12.55 -0.56 5.68e-30 Eosinophil percentage of white cells; LIHC cis rs9430161 0.579 rs7542164 chr1:11040223 G/A cg27631724 chr1:11040367 C1orf127 0.38 7.75 0.39 1.05e-13 Ewing sarcoma; LIHC cis rs950169 1.000 rs35658069 chr15:84780146 C/T cg17507749 chr15:85114479 UBE2QP1 0.76 7.75 0.39 1.03e-13 Schizophrenia; LIHC cis rs7617773 0.817 rs9311421 chr3:48293078 G/A cg11946769 chr3:48343235 NME6 0.87 11.09 0.51 1.25e-24 Coronary artery disease; LIHC cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 12.63 0.56 2.73e-30 Alzheimer's disease; LIHC cis rs919433 0.617 rs700638 chr2:198588950 A/C cg00792783 chr2:198669748 PLCL1 0.43 6.24 0.32 1.32e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11098499 0.874 rs12509054 chr4:120115075 A/C cg09307838 chr4:120376055 NA 0.52 7.74 0.39 1.16e-13 Corneal astigmatism; LIHC cis rs5769765 0.908 rs138864 chr22:50204712 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.68 -8.26 -0.41 3.29e-15 Schizophrenia; LIHC cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.48 -7.29 -0.37 2.24e-12 Tuberculosis; LIHC cis rs4824093 0.610 rs77128035 chr22:50241024 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.74 -5.9 -0.3 8.65e-9 Amyotrophic lateral sclerosis (sporadic); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23477849 chr19:5698492 LONP1 0.44 6.49 0.33 3.07e-10 Longevity; LIHC cis rs7618501 0.572 rs4688756 chr3:50040194 T/A cg24110177 chr3:50126178 RBM5 -0.47 -7.65 -0.38 2.08e-13 Intelligence (multi-trait analysis); LIHC trans rs3960554 0.610 rs10265696 chr7:75766712 G/A cg19862616 chr7:65841803 NCRNA00174 0.6 8.33 0.41 2.01e-15 Eotaxin levels; LIHC cis rs672413 0.739 rs500390 chr5:78283656 C/T cg26802063 chr5:78281964 ARSB -0.39 -6.34 -0.32 7.35e-10 Blood and toenail selenium levels;Blood protein levels; LIHC cis rs733592 0.524 rs10875741 chr12:48492922 A/C cg21466736 chr12:48725269 NA 0.33 5.92 0.3 7.87e-9 Plateletcrit; LIHC cis rs2153535 0.580 rs7341201 chr6:8470270 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs9457247 1.000 rs389946 chr6:167407268 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.14 -0.52 8.58e-25 Crohn's disease; LIHC cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg23172400 chr8:95962367 TP53INP1 -0.35 -7.85 -0.39 5.44e-14 Type 2 diabetes; LIHC cis rs7927592 0.717 rs7126451 chr11:68257386 A/G cg20283391 chr11:68216788 NA 0.4 6.36 0.33 6.6e-10 Total body bone mineral density; LIHC cis rs709400 0.628 rs2273700 chr14:103923414 A/G cg26031613 chr14:104095156 KLC1 0.77 9.97 0.47 9.88e-21 Body mass index; LIHC cis rs754466 0.606 rs11002306 chr10:79591519 A/T cg17075019 chr10:79541650 NA -0.78 -12.11 -0.55 2.41e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg12379764 chr21:47803548 PCNT 0.54 7.97 0.4 2.39e-14 Testicular germ cell tumor; LIHC cis rs763121 0.819 rs5750629 chr22:38985065 T/C cg14440974 chr22:39074834 NA -0.35 -5.9 -0.3 8.63e-9 Menopause (age at onset); LIHC cis rs2404602 0.622 rs1567671 chr15:77209200 C/G cg03037974 chr15:76606532 NA -0.56 -9.36 -0.45 1.1e-18 Blood metabolite levels; LIHC cis rs11758351 0.789 rs2069020 chr6:26205500 C/T cg03785755 chr6:26196794 NA 0.52 5.95 0.31 6.49e-9 Gout;Renal underexcretion gout; LIHC trans rs11782824 1.000 rs11782824 chr8:38781040 A/C cg24305797 chr16:9185438 C16orf72 -0.45 -6.58 -0.34 1.78e-10 Neuroticism; LIHC cis rs10876993 0.890 rs10783844 chr12:58098425 A/C cg18357645 chr12:58087776 OS9 0.52 8.46 0.42 7.86e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg09222892 chr1:25734099 RHCE -0.48 -8.9 -0.43 3.36e-17 Erythrocyte sedimentation rate; LIHC cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg12310025 chr6:25882481 NA -0.72 -9.32 -0.45 1.44e-18 Intelligence (multi-trait analysis); LIHC trans rs459571 0.959 rs2810491 chr9:136923331 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 0.55 8.23 0.41 3.98e-15 Platelet distribution width; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg16405210 chr4:1374714 KIAA1530 -0.9 -14.94 -0.63 3.49e-39 Longevity; LIHC cis rs548181 0.609 rs511822 chr11:125534115 C/T cg03464685 chr11:125439445 EI24 0.91 10.02 0.48 7.06e-21 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7618501 0.521 rs3774759 chr3:49939120 G/T cg05623727 chr3:50126028 RBM5 0.35 5.88 0.3 9.73e-9 Intelligence (multi-trait analysis); LIHC trans rs8073060 0.586 rs225280 chr17:33976296 C/T cg19694781 chr19:47549865 TMEM160 -1.24 -12.96 -0.57 1.55e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2439831 0.681 rs825739 chr15:43592428 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.87 16.27 0.66 1.73e-44 Lung cancer in ever smokers; LIHC cis rs7674212 0.570 rs2069274 chr4:104020781 C/G cg16532752 chr4:104119610 CENPE -0.46 -7.14 -0.36 5.81e-12 Type 2 diabetes; LIHC cis rs12142240 0.698 rs1984490 chr1:46858734 C/T cg14993813 chr1:46806288 NSUN4 0.64 5.96 0.31 6.31e-9 Menopause (age at onset); LIHC cis rs7091068 0.616 rs7901507 chr10:95505424 C/G cg20715218 chr10:95462985 C10orf4 0.56 5.85 0.3 1.12e-8 Urinary tract infection frequency; LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.82 16.82 0.67 1.14e-46 Prudent dietary pattern; LIHC cis rs8084351 0.599 rs4940246 chr18:50717386 T/C cg24270629 chr18:50823537 DCC -0.44 -6.54 -0.33 2.29e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9916302 0.904 rs585961 chr17:37444036 G/A cg00129232 chr17:37814104 STARD3 0.38 6.07 0.31 3.37e-9 Glomerular filtration rate (creatinine); LIHC cis rs2204008 0.626 rs11520260 chr12:38330092 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.57e-15 Bladder cancer; LIHC cis rs7523273 0.606 rs2724398 chr1:207993699 A/G cg22525895 chr1:207977042 MIR29B2 -0.62 -9.88 -0.47 2.12e-20 Schizophrenia; LIHC cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg02353165 chr6:42928485 GNMT 0.95 15.38 0.64 6.02e-41 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9322817 0.583 rs6571202 chr6:105182644 G/T cg02098413 chr6:105308735 HACE1 -0.43 -7.72 -0.39 1.33e-13 Thyroid stimulating hormone; LIHC cis rs4934494 0.727 rs12570750 chr10:91521030 G/A cg19698084 chr10:91461284 KIF20B -0.44 -5.88 -0.3 9.5e-9 Red blood cell count; LIHC cis rs921968 0.541 rs578450 chr2:219401237 C/T cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg03806693 chr22:41940476 POLR3H 0.97 10.4 0.49 3.29e-22 Vitiligo; LIHC cis rs526231 0.819 rs35803 chr5:102606942 A/G cg05225461 chr5:102596755 C5orf30 0.38 5.85 0.3 1.16e-8 Primary biliary cholangitis; LIHC cis rs919433 0.680 rs7590010 chr2:198400668 C/T cg03934865 chr2:198174659 NA 0.51 7.67 0.38 1.83e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2204008 0.729 rs2892365 chr12:38446760 G/C cg26384229 chr12:38710491 ALG10B -0.59 -8.55 -0.42 4.27e-16 Bladder cancer; LIHC cis rs35110281 0.666 rs9977076 chr21:45085829 G/A cg04455712 chr21:45112962 RRP1B 0.5 8.35 0.41 1.78e-15 Mean corpuscular volume; LIHC cis rs12477438 0.520 rs7572660 chr2:99788582 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.16 0.77 4.33e-68 Chronic sinus infection; LIHC cis rs11718455 0.960 rs4682712 chr3:43997971 T/C cg08738300 chr3:44038990 NA 0.52 9.0 0.44 1.56e-17 Coronary artery disease; LIHC cis rs589448 0.535 rs12423794 chr12:69713018 G/A cg20891283 chr12:69753455 YEATS4 0.86 16.97 0.68 2.81e-47 Cerebrospinal fluid biomarker levels; LIHC cis rs6542838 0.582 rs6542845 chr2:99537600 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.45 -7.37 -0.37 1.31e-12 Fear of minor pain; LIHC cis rs12701220 0.948 rs12690826 chr7:1081618 A/G cg26769984 chr7:1090371 C7orf50 0.63 7.94 0.39 2.86e-14 Bronchopulmonary dysplasia; LIHC cis rs6502050 0.835 rs7406529 chr17:80080877 C/T cg13198984 chr17:80129470 CCDC57 -0.33 -5.8 -0.3 1.54e-8 Life satisfaction; LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.74 0.39 1.13e-13 Prudent dietary pattern; LIHC cis rs1823913 0.927 rs13013390 chr2:192126727 A/G cg12404831 chr2:192114017 MYO1B 0.32 6.59 0.34 1.62e-10 Obesity-related traits; LIHC cis rs28830936 0.510 rs11858843 chr15:42092915 C/A cg17847044 chr15:42102381 MAPKBP1 -0.48 -11.6 -0.53 1.86e-26 Diastolic blood pressure; LIHC cis rs780096 0.545 rs11695549 chr2:27586155 A/C cg27432699 chr2:27873401 GPN1 -0.49 -6.8 -0.35 4.62e-11 Total body bone mineral density; LIHC cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg11890956 chr21:40555474 PSMG1 1.05 14.96 0.63 2.83e-39 Cognitive function; LIHC cis rs4819052 0.918 rs2330013 chr21:46658662 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.7 9.36 0.45 1.1e-18 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1005277 0.522 rs9417256 chr10:37976990 A/G cg00409905 chr10:38381863 ZNF37A -0.56 -9.73 -0.47 6.71e-20 Extrinsic epigenetic age acceleration; LIHC cis rs7945705 0.902 rs2568059 chr11:8884161 T/C cg12365402 chr11:9010492 NRIP3 -0.25 -6.3 -0.32 9.39e-10 Hemoglobin concentration; LIHC cis rs7582180 0.629 rs11693471 chr2:100948062 G/A cg14675211 chr2:100938903 LONRF2 0.53 8.41 0.41 1.13e-15 Intelligence (multi-trait analysis); LIHC cis rs11645898 0.504 rs75888697 chr16:71985222 A/C cg03805757 chr16:71968109 PKD1L3 -0.81 -7.9 -0.39 3.84e-14 Blood protein levels; LIHC cis rs17818399 0.926 rs13033177 chr2:46831062 C/A cg02822958 chr2:46747628 ATP6V1E2 0.45 6.84 0.35 3.61e-11 Height; LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg20887711 chr4:1340912 KIAA1530 -0.77 -11.8 -0.54 3.36e-27 Longevity; LIHC cis rs8017423 0.967 rs11623275 chr14:90721335 C/T cg04374321 chr14:90722782 PSMC1 0.77 15.19 0.63 3.32e-40 Mortality in heart failure; LIHC cis rs11628318 0.715 rs1815262 chr14:103056926 C/T cg23461800 chr14:103021989 NA -0.44 -5.97 -0.31 5.95e-9 Platelet count; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg12544020 chr12:15941292 EPS8 0.36 6.06 0.31 3.64e-9 Calcium levels; LIHC cis rs11112613 0.762 rs66754070 chr12:105949779 G/A cg03607813 chr12:105948248 NA 0.66 13.22 0.58 1.65e-32 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7312933 0.865 rs1920687 chr12:42398275 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.46 6.62 0.34 1.39e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs8067354 0.789 rs4622571 chr17:57884397 T/A cg13753209 chr17:57696993 CLTC 0.58 8.93 0.43 2.68e-17 Hemoglobin concentration; LIHC cis rs4268898 0.662 rs72793213 chr2:24524725 A/G cg06627628 chr2:24431161 ITSN2 -0.72 -9.82 -0.47 3.29e-20 Asthma; LIHC trans rs9914544 0.545 rs4510081 chr17:18798846 A/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.65 -0.34 1.16e-10 Educational attainment (years of education); LIHC cis rs2832191 0.646 rs2832210 chr21:30508723 T/G cg08807101 chr21:30365312 RNF160 -0.41 -5.8 -0.3 1.55e-8 Dental caries; LIHC cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg03517284 chr6:25882590 NA -0.62 -8.77 -0.43 8.61e-17 Blood metabolite levels; LIHC cis rs1371867 0.846 rs1692007 chr8:101268343 T/C cg06636551 chr8:101224915 SPAG1 0.49 9.27 0.45 2.12e-18 Atrioventricular conduction; LIHC cis rs7312774 0.748 rs12320535 chr12:107295813 T/C cg16260113 chr12:107380972 MTERFD3 0.78 10.17 0.48 2.15e-21 Severe influenza A (H1N1) infection; LIHC cis rs9583531 0.657 rs7337126 chr13:111376788 A/G cg24331049 chr13:111365604 ING1 0.8 13.17 0.58 2.5e-32 Coronary artery disease; LIHC cis rs782590 0.729 rs706548 chr2:55850106 C/G cg18811423 chr2:55921094 PNPT1 0.91 13.61 0.59 5.3e-34 Metabolic syndrome; LIHC cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg08219700 chr8:58056026 NA 0.53 6.78 0.34 5.4e-11 Developmental language disorder (linguistic errors); LIHC cis rs882732 1.000 rs1005348 chr14:95033275 T/G cg14866387 chr14:95027382 SERPINA4 -0.46 -6.83 -0.35 3.99e-11 Blood protein levels; LIHC cis rs2573652 0.674 rs11630583 chr15:100543355 G/A cg09918751 chr15:100517450 ADAMTS17 -0.69 -11.98 -0.54 7.7e-28 Height; LIHC cis rs10259085 0.647 rs11767988 chr7:7264359 A/C cg04827551 chr7:7268805 C1GALT1 0.33 6.16 0.32 2.06e-9 Multiple sclerosis (severity); LIHC cis rs986417 1.000 rs1955686 chr14:61093560 C/T cg27398547 chr14:60952738 C14orf39 0.65 6.51 0.33 2.69e-10 Gut microbiota (bacterial taxa); LIHC cis rs9560113 0.881 rs9560111 chr13:112181289 C/T cg14154082 chr13:112174009 NA 0.3 6.39 0.33 5.52e-10 Menarche (age at onset); LIHC cis rs2228479 0.717 rs1800358 chr16:89809319 T/C cg06558623 chr16:89946397 TCF25 0.82 11.52 0.53 3.71e-26 Skin colour saturation; LIHC cis rs1355223 0.583 rs2956076 chr11:34874124 T/C cg11058730 chr11:34937778 PDHX;APIP 0.74 12.63 0.56 2.74e-30 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs941408 0.515 rs1005556 chr19:2778543 G/T cg19676328 chr12:49525230 TUBA1B -0.42 -6.06 -0.31 3.53e-9 Total cholesterol levels; LIHC trans rs561341 0.883 rs1034626 chr17:30219500 C/G cg20587970 chr11:113659929 NA 0.69 8.12 0.4 8.67e-15 Hip circumference adjusted for BMI; LIHC cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.54e-26 Alzheimer's disease; LIHC cis rs1008375 0.902 rs12503164 chr4:17656107 C/T cg16339924 chr4:17578868 LAP3 0.45 6.33 0.32 7.87e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs904251 0.828 rs2797803 chr6:37487340 T/C cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.47e-9 Cognitive performance; LIHC cis rs7255436 0.965 rs11666003 chr19:8452102 G/A cg10174797 chr19:8464628 RAB11B 0.42 5.74 0.3 2.04e-8 HDL cholesterol; LIHC cis rs826838 1.000 rs11514441 chr12:38775190 C/T cg26384229 chr12:38710491 ALG10B 1.05 14.05 0.6 1.05e-35 Heart rate; LIHC cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg05665937 chr4:1216051 CTBP1 0.46 6.19 0.32 1.71e-9 Obesity-related traits; LIHC cis rs4834770 1.000 rs4834770 chr4:120241849 A/G cg09307838 chr4:120376055 NA 0.43 6.39 0.33 5.52e-10 Blood protein levels; LIHC cis rs240764 0.548 rs12206838 chr6:101180128 G/A cg12253828 chr6:101329408 ASCC3 -0.39 -6.02 -0.31 4.38e-9 Neuroticism; LIHC cis rs506338 0.517 rs530252 chr11:64443465 T/C cg27209729 chr11:64428925 NRXN2 0.35 6.54 0.33 2.2e-10 Body mass index;Urate levels; LIHC cis rs6912958 0.605 rs2754247 chr6:88383571 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.43 -7.55 -0.38 3.95e-13 Monocyte percentage of white cells; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg16132339 chr22:24313637 DDTL;DDT 0.73 13.9 0.6 3.81e-35 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4638749 0.677 rs10189396 chr2:108829637 A/G cg06795125 chr2:108905320 SULT1C2 -0.3 -6.01 -0.31 4.69e-9 Blood pressure; LIHC cis rs867186 0.614 rs76163454 chr20:33451706 G/A cg08999081 chr20:33150536 PIGU 0.64 5.79 0.3 1.61e-8 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs4934494 0.813 rs34928397 chr10:91526599 T/G cg19698084 chr10:91461284 KIF20B -0.44 -5.83 -0.3 1.26e-8 Red blood cell count; LIHC cis rs477692 0.935 rs554458 chr10:131427372 A/G cg05714579 chr10:131428358 MGMT 0.5 8.48 0.42 6.95e-16 Response to temozolomide; LIHC cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.26 -0.61 1.62e-36 Alzheimer's disease; LIHC cis rs703842 0.739 rs701008 chr12:58117645 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.59 8.82 0.43 6.07e-17 Multiple sclerosis; LIHC trans rs8002861 0.870 rs9567293 chr13:44447243 A/G cg17145862 chr1:211918768 LPGAT1 0.51 8.44 0.42 9.43e-16 Leprosy; LIHC trans rs1005277 0.579 rs11011461 chr10:38431427 G/A cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2439831 0.867 rs2447211 chr15:43936351 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.87 0.35 3.04e-11 Lung cancer in ever smokers; LIHC cis rs116248771 0.793 rs73156465 chr3:158374535 C/G cg16708174 chr3:158430962 RARRES1 0.48 6.38 0.33 5.61e-10 diarrhoeal disease at age 2; LIHC cis rs9628987 0.500 rs11121179 chr1:8455712 G/T cg20416874 chr1:8611966 RERE 0.49 5.82 0.3 1.36e-8 Breast cancer; LIHC cis rs701145 0.617 rs7426835 chr3:154049539 C/T cg16511985 chr3:153974050 SGEF 0.4 8.41 0.41 1.14e-15 Coronary artery disease; LIHC cis rs651907 0.535 rs17412601 chr3:101499275 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.53 -0.46 3.03e-19 Initial pursuit acceleration; LIHC cis rs9325144 0.600 rs10880934 chr12:38730455 C/T cg26384229 chr12:38710491 ALG10B -0.56 -7.67 -0.38 1.81e-13 Morning vs. evening chronotype; LIHC cis rs9309473 0.898 rs7587577 chr2:73832786 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.44 -0.33 3.98e-10 Metabolite levels; LIHC cis rs875971 0.545 rs316323 chr7:65610989 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.37 -7.5 -0.38 5.7e-13 Aortic root size; LIHC cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg21280719 chr6:42927975 GNMT -0.32 -7.5 -0.38 5.65e-13 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3820068 0.581 rs1547033 chr1:15918988 T/C cg17385448 chr1:15911702 AGMAT 0.35 5.94 0.31 7.07e-9 Systolic blood pressure; LIHC cis rs2404602 0.692 rs58889902 chr15:77173070 A/C cg23625390 chr15:77176239 SCAPER 0.35 5.74 0.3 2.04e-8 Blood metabolite levels; LIHC cis rs4638749 0.677 rs6711297 chr2:108818357 A/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.71 -0.34 8.07e-11 Blood pressure; LIHC cis rs7772486 0.754 rs6922507 chr6:146250155 A/T cg23711669 chr6:146136114 FBXO30 -0.71 -12.43 -0.56 1.64e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs2439831 0.867 rs4075674 chr15:43650230 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.75 11.01 0.51 2.55e-24 Lung cancer in ever smokers; LIHC cis rs17854409 0.764 rs12625513 chr20:61475661 G/A cg05147244 chr20:61493195 TCFL5 1.3 10.44 0.49 2.5e-22 Obesity-related traits; LIHC cis rs10792665 0.610 rs10751081 chr11:82560697 A/G cg24227371 chr11:82718527 RAB30 -0.25 -6.04 -0.31 4.12e-9 Obesity-related traits; LIHC cis rs6696846 0.791 rs7520752 chr1:205054114 C/T cg21545522 chr1:205238299 TMCC2 -0.32 -6.17 -0.32 1.89e-9 Red blood cell count; LIHC cis rs10791323 0.660 rs2156681 chr11:133731644 G/T cg06766960 chr11:133703094 NA -0.6 -9.61 -0.46 1.7e-19 Childhood ear infection; LIHC cis rs35110281 0.807 rs4818850 chr21:45028071 T/G cg01579765 chr21:45077557 HSF2BP -0.33 -6.21 -0.32 1.52e-9 Mean corpuscular volume; LIHC cis rs12579753 1.000 rs34031374 chr12:82235615 G/C cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs10779751 0.959 rs2300091 chr1:11266711 C/T cg08854313 chr1:11322531 MTOR 0.86 15.56 0.64 1.14e-41 Body mass index; LIHC trans rs1814175 0.519 rs3913237 chr11:49551828 G/A cg03929089 chr4:120376271 NA 0.69 10.12 0.48 3.01e-21 Height; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg22135468 chr22:20104774 TRMT2A;RANBP1 0.47 6.04 0.31 4.04e-9 Hepatitis; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg24441383 chr12:19459574 PLEKHA5 0.42 6.17 0.32 1.98e-9 Immature fraction of reticulocytes; LIHC cis rs7264396 0.563 rs2425089 chr20:34304036 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC cis rs506338 0.517 rs530775 chr11:64426933 A/G cg08800856 chr11:64428347 NRXN2 0.37 5.8 0.3 1.49e-8 Body mass index;Urate levels; LIHC cis rs763121 0.853 rs5757234 chr22:39072686 C/T cg14440974 chr22:39074834 NA -0.36 -6.12 -0.31 2.63e-9 Menopause (age at onset); LIHC cis rs16828019 0.852 rs12742379 chr1:41526381 A/G cg03387723 chr1:41708464 SCMH1 -0.41 -6.7 -0.34 8.63e-11 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg06634786 chr22:41940651 POLR3H -0.78 -8.09 -0.4 1.05e-14 Vitiligo; LIHC cis rs757081 0.671 rs214072 chr11:17305270 C/T cg15432903 chr11:17409602 KCNJ11 -0.45 -5.96 -0.31 6.28e-9 Systolic blood pressure; LIHC cis rs17428076 0.793 rs72881938 chr2:172628752 C/G cg13550731 chr2:172543902 DYNC1I2 0.4 6.6 0.34 1.55e-10 Myopia; LIHC cis rs9611565 0.512 rs132784 chr22:42052363 G/A cg06634786 chr22:41940651 POLR3H 0.73 7.36 0.37 1.35e-12 Vitiligo; LIHC cis rs2073300 0.609 rs8183135 chr20:23384284 C/T cg12062639 chr20:23401060 NAPB 1.08 14.26 0.61 1.61e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6673480 0.541 rs67377357 chr1:51498067 G/C cg07174182 chr1:51127561 FAF1 -0.75 -8.71 -0.43 1.31e-16 IgE grass sensitization; LIHC cis rs4319547 0.741 rs4758663 chr12:122939483 A/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.38 -0.37 1.25e-12 Body mass index; LIHC cis rs6426558 0.537 rs4500279 chr1:227484482 G/A cg10327440 chr1:227177885 CDC42BPA 0.4 6.22 0.32 1.48e-9 Neutrophil percentage of white cells; LIHC cis rs11112613 0.775 rs10507194 chr12:105959488 G/A cg03607813 chr12:105948248 NA 0.62 11.84 0.54 2.52e-27 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs72634258 0.836 rs7545687 chr1:7997183 G/A cg01095510 chr12:26267286 NA 0.58 6.78 0.34 5.42e-11 Inflammatory bowel disease; LIHC cis rs2439831 0.867 rs4583210 chr15:43660925 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.94 17.38 0.68 6.24e-49 Lung cancer in ever smokers; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03425217 chr10:27443402 YME1L1;MASTL -0.45 -6.92 -0.35 2.25e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1400745 0.756 rs3783314 chr14:35337384 T/C cg16230307 chr14:35515116 FAM177A1 0.38 6.2 0.32 1.63e-9 Monocyte count; LIHC cis rs6952808 0.729 rs35797753 chr7:1954914 G/A cg20295408 chr7:1910781 MAD1L1 -0.51 -7.19 -0.36 4.08e-12 Bipolar disorder and schizophrenia; LIHC trans rs9951602 0.512 rs9946115 chr18:76654531 A/C cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs754466 0.580 rs2289308 chr10:79579251 G/A cg17075019 chr10:79541650 NA -0.8 -12.34 -0.56 3.33e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs743757 0.938 rs2236981 chr3:50488845 A/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.16 0.32 2.04e-9 Diastolic blood pressure; LIHC cis rs5770917 1.000 rs1056964 chr22:51017476 A/G cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.42 -6.16 -0.32 2.07e-9 Narcolepsy; LIHC trans rs13381277 0.850 rs1110158 chr18:74330660 A/G cg17352830 chr21:37617589 DOPEY2 -0.55 -6.34 -0.32 7.27e-10 Dental caries; LIHC cis rs2625529 0.938 rs2625530 chr15:72126034 G/A cg16672083 chr15:72433130 SENP8 -0.32 -5.98 -0.31 5.66e-9 Red blood cell count; LIHC cis rs769267 0.931 rs2965193 chr19:19454828 G/A cg03709012 chr19:19516395 GATAD2A -0.93 -16.03 -0.65 1.59e-43 Tonsillectomy; LIHC cis rs9378688 0.654 rs2505677 chr6:2346248 T/A cg12303981 chr6:2244766 GMDS -0.45 -6.07 -0.31 3.43e-9 Caudate nucleus volume; LIHC cis rs763121 0.626 rs5750643 chr22:39009017 A/G cg21395723 chr22:39101663 GTPBP1 0.39 6.64 0.34 1.24e-10 Menopause (age at onset); LIHC cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg21724239 chr8:58056113 NA 0.56 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs801193 1.000 rs2659912 chr7:66157999 G/C cg00343986 chr7:65444356 GUSB 0.39 5.85 0.3 1.14e-8 Aortic root size; LIHC cis rs10197940 0.662 rs72860233 chr2:152289767 G/A cg06191203 chr2:152266755 RIF1 -0.48 -8.09 -0.4 1.02e-14 Lung cancer; LIHC cis rs7312933 0.567 rs11181399 chr12:42666412 G/A cg01256987 chr12:42539512 GXYLT1 -0.4 -6.59 -0.34 1.63e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs12586317 0.508 rs10134914 chr14:35425012 T/G cg05294307 chr14:35346193 BAZ1A -0.47 -7.35 -0.37 1.45e-12 Psoriasis; LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.01 21.96 0.76 2.7e-67 Height; LIHC cis rs926392 0.932 rs6513588 chr20:37686281 T/C cg16355469 chr20:37678765 NA 0.37 5.99 0.31 5.37e-9 Dialysis-related mortality; LIHC trans rs2727020 0.521 rs10839285 chr11:49496852 T/G cg03929089 chr4:120376271 NA 0.7 10.66 0.5 4.09e-23 Coronary artery disease; LIHC trans rs1814175 0.645 rs10128563 chr11:50023681 T/C cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs3729931 0.507 rs79945102 chr3:12711975 A/C cg23032965 chr3:12705835 RAF1 0.6 6.63 0.34 1.34e-10 Cardiac hypertrophy; LIHC cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg23205692 chr1:25664452 TMEM50A -0.37 -6.01 -0.31 4.67e-9 Erythrocyte sedimentation rate; LIHC cis rs5769765 1.000 rs4824106 chr22:50267822 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs10857712 0.754 rs2297031 chr10:135232654 C/T cg01444801 chr10:135216882 MTG1 -0.65 -9.67 -0.46 1.01e-19 Systemic lupus erythematosus; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg12823748 chr12:62654080 USP15 0.45 6.75 0.34 6.44e-11 Calcium levels; LIHC trans rs7613875 0.600 rs2856238 chr3:50158191 C/T cg21659725 chr3:3221576 CRBN 0.55 8.26 0.41 3.16e-15 Body mass index; LIHC cis rs757110 0.803 rs7928810 chr11:17372443 G/T cg15432903 chr11:17409602 KCNJ11 0.65 10.0 0.48 7.84e-21 Type 2 diabetes; LIHC cis rs4984778 0.750 rs7198064 chr16:1272472 C/T cg07748719 chr16:1272498 TPSG1 0.47 6.8 0.34 4.82e-11 Blood protein levels; LIHC cis rs941873 0.838 rs2233713 chr10:81107135 A/C cg11057378 chr10:81107060 PPIF 0.37 5.98 0.31 5.64e-9 Height; LIHC trans rs12478296 0.681 rs56357900 chr2:243033966 A/C cg01596870 chr19:55963115 NA -0.62 -8.17 -0.4 5.86e-15 Obesity-related traits; LIHC cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg03264133 chr6:25882463 NA 0.84 11.39 0.52 1.05e-25 Blood metabolite levels; LIHC cis rs67981189 0.574 rs2526880 chr14:71375338 C/T cg15816911 chr14:71606274 NA -0.42 -6.72 -0.34 7.45e-11 Schizophrenia; LIHC cis rs4132509 1.000 rs10927076 chr1:243958293 A/G cg21452805 chr1:244014465 NA 0.46 6.13 0.31 2.4e-9 RR interval (heart rate); LIHC cis rs1580019 0.844 rs1584615 chr7:32503258 G/C cg07520158 chr7:32535189 LSM5;AVL9 0.5 6.74 0.34 6.57e-11 Cognitive ability; LIHC cis rs7582720 1.000 rs72934764 chr2:203758521 C/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7089973 0.604 rs11196939 chr10:116593175 A/G cg03647239 chr10:116582469 FAM160B1 -0.43 -5.99 -0.31 5.25e-9 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs1945213 0.694 rs7131381 chr11:55858158 T/G cg15704280 chr7:45808275 SEPT13 0.59 7.68 0.38 1.71e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs6449957 0.577 rs7707370 chr5:67529747 T/C cg23036683 chr5:67512108 NA 0.42 6.02 0.31 4.55e-9 Cleft lip with or without cleft palate; LIHC cis rs4474465 0.833 rs10793317 chr11:78212011 G/A cg27205649 chr11:78285834 NARS2 0.39 5.79 0.3 1.57e-8 Alzheimer's disease (survival time); LIHC cis rs9467773 1.000 rs4871 chr6:26545632 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.9 0.6 4.02e-35 Intelligence (multi-trait analysis); LIHC cis rs910316 0.967 rs4903292 chr14:75656245 A/G cg11812906 chr14:75593930 NEK9 0.66 12.55 0.56 5.72e-30 Height; LIHC cis rs546131 0.820 rs744841 chr11:34857667 G/A cg06937548 chr11:34938143 PDHX;APIP 0.64 8.66 0.42 1.85e-16 Lung disease severity in cystic fibrosis; LIHC cis rs17685 0.712 rs2158867 chr7:75815141 C/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.36 -5.83 -0.3 1.3e-8 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10791323 0.581 rs2723608 chr11:133710149 A/G cg06766960 chr11:133703094 NA -0.67 -11.24 -0.52 3.68e-25 Childhood ear infection; LIHC cis rs116095464 0.558 rs7356561 chr5:284381 G/C cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs12477438 0.798 rs972768 chr2:99682397 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.85 -0.65 8.31e-43 Chronic sinus infection; LIHC cis rs7131987 0.903 rs11050163 chr12:29420398 C/T cg14222432 chr12:29376421 FAR2 0.36 6.87 0.35 3.11e-11 QT interval; LIHC cis rs6061231 1.000 rs11696991 chr20:60959694 G/T cg24112000 chr20:60950667 NA -0.67 -10.46 -0.49 2.04e-22 Colorectal cancer; LIHC cis rs4906332 1.000 rs2065017 chr14:103879579 T/C cg04998671 chr14:104000505 TRMT61A -0.45 -6.23 -0.32 1.34e-9 Coronary artery disease; LIHC cis rs611744 0.846 rs405534 chr8:109154408 T/A cg21045802 chr8:109455806 TTC35 0.49 8.21 0.41 4.58e-15 Dupuytren's disease; LIHC cis rs1707322 0.721 rs6429574 chr1:46134054 A/G cg03146154 chr1:46216737 IPP 0.58 10.32 0.49 6.53e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs539514 0.563 rs7983875 chr13:76329245 T/C cg04757411 chr13:76259545 LMO7 -0.42 -7.01 -0.35 1.25e-11 Type 1 diabetes; LIHC cis rs61008539 0.586 rs6959154 chr7:856320 C/T cg05535760 chr7:792225 HEATR2 -0.52 -7.0 -0.35 1.33e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs12893668 0.572 rs12590968 chr14:104136633 G/C cg24130564 chr14:104152367 KLC1 -0.55 -9.5 -0.46 3.67e-19 Reticulocyte count; LIHC cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs1408224 0.688 rs866376 chr13:47230865 A/G cg04092803 chr13:47240378 LRCH1 -0.43 -6.8 -0.35 4.65e-11 QRS complex (12-leadsum); LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg26354017 chr1:205819088 PM20D1 0.81 11.45 0.53 6.46e-26 Menarche (age at onset); LIHC cis rs6089584 0.893 rs6089306 chr20:60574868 G/A cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC trans rs4650994 0.524 rs2476558 chr1:178580953 C/T cg05059571 chr16:84539110 KIAA1609 0.43 7.22 0.36 3.33e-12 HDL cholesterol levels;HDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07152487 chr11:14665355 PDE3B;PSMA1 0.45 6.23 0.32 1.34e-9 Lung function (FEV1/FVC); LIHC trans rs11098499 0.954 rs13145352 chr4:120409963 C/T cg25214090 chr10:38739885 LOC399744 -0.53 -8.15 -0.4 7.06e-15 Corneal astigmatism; LIHC cis rs921968 0.541 rs3845835 chr2:219342284 T/C cg02176678 chr2:219576539 TTLL4 -0.56 -7.76 -0.39 1e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20022216 chr4:39700309 UBE2K 0.45 6.33 0.32 7.88e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg27432699 chr2:27873401 GPN1 -0.49 -7.19 -0.36 4.13e-12 Total body bone mineral density; LIHC cis rs7927592 0.763 rs10896327 chr11:68235275 G/C cg01657329 chr11:68192670 LRP5 -0.48 -7.02 -0.36 1.17e-11 Total body bone mineral density; LIHC cis rs4925386 0.819 rs2890083 chr20:60911958 G/A cg24112000 chr20:60950667 NA 0.45 7.12 0.36 6.25e-12 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs9814567 1.000 rs9829092 chr3:134229866 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.38 -0.56 2.41e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9902453 0.904 rs12936302 chr17:28349476 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -13.44 -0.59 2.26e-33 Coffee consumption (cups per day); LIHC cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.58 -0.34 1.75e-10 Gut microbiome composition (summer); LIHC cis rs2836974 0.583 rs2776306 chr21:40713754 A/G cg11890956 chr21:40555474 PSMG1 0.58 8.66 0.42 1.91e-16 Cognitive function; LIHC cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg13395646 chr4:1353034 KIAA1530 -0.63 -8.99 -0.44 1.66e-17 Obesity-related traits; LIHC cis rs8044868 0.512 rs10048144 chr16:72052891 C/G cg01557791 chr16:72042693 DHODH -0.41 -6.92 -0.35 2.27e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg16049864 chr8:95962084 TP53INP1 -0.6 -11.34 -0.52 1.68e-25 Type 2 diabetes; LIHC cis rs7208859 0.623 rs9899268 chr17:29150255 T/C cg14067834 chr17:29058358 SUZ12P 0.68 6.62 0.34 1.38e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28830936 1.000 rs2004162 chr15:41965542 A/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -5.8 -0.3 1.49e-8 Diastolic blood pressure; LIHC cis rs10078 0.515 rs890984 chr5:479540 A/G cg07599136 chr5:415885 AHRR 0.77 12.62 0.56 3.11e-30 Fat distribution (HIV); LIHC cis rs722599 0.748 rs3742783 chr14:75377008 C/T cg11812906 chr14:75593930 NEK9 -0.44 -7.11 -0.36 6.98e-12 IgG glycosylation; LIHC cis rs12477438 0.501 rs11683107 chr2:99759235 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.13 0.61 5.14e-36 Chronic sinus infection; LIHC cis rs10078 0.559 rs2672725 chr5:434981 G/C cg08916839 chr5:415575 AHRR 0.6 12.59 0.56 4.09e-30 Fat distribution (HIV); LIHC cis rs2997447 0.846 rs61775430 chr1:26411109 G/A cg19633962 chr1:26362018 EXTL1 -0.7 -6.4 -0.33 5.06e-10 QRS complex (12-leadsum); LIHC cis rs2204008 0.837 rs11612125 chr12:38213212 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs892961 0.932 rs7208671 chr17:75413129 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs79387448 0.655 rs11891827 chr2:102951182 A/G cg09003973 chr2:102972529 NA 1.16 9.53 0.46 3.06e-19 Gut microbiota (bacterial taxa); LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg12064134 chr16:90016061 DEF8 -0.44 -5.96 -0.31 6.44e-9 Interleukin-17 levels; LIHC cis rs898097 0.801 rs68141193 chr17:80878816 C/T cg15664640 chr17:80829946 TBCD -0.74 -12.03 -0.55 5.06e-28 Breast cancer; LIHC trans rs9926296 0.542 rs12599531 chr16:89909401 C/T cg13698153 chr12:118541722 VSIG10 -0.65 -6.92 -0.35 2.24e-11 Vitiligo; LIHC cis rs9916302 0.904 rs11869109 chr17:37518205 G/T cg03013999 chr17:37608204 MED1 -0.35 -5.93 -0.31 7.41e-9 Glomerular filtration rate (creatinine); LIHC cis rs35306767 0.855 rs11253465 chr10:897208 A/C cg26597838 chr10:835615 NA 1.13 13.37 0.59 4.36e-33 Eosinophil percentage of granulocytes; LIHC cis rs6951245 0.554 rs58210047 chr7:1149381 G/A cg04025307 chr7:1156635 C7orf50 0.65 6.56 0.33 2.02e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12478296 1.000 rs6739247 chr2:243039189 C/A cg18898632 chr2:242989856 NA -0.58 -7.83 -0.39 6.11e-14 Obesity-related traits; LIHC cis rs6088813 0.890 rs6088817 chr20:33984976 T/C cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC trans rs916888 0.610 rs199529 chr17:44837217 A/C cg26692224 chr17:62915920 LRRC37A3 -0.69 -6.77 -0.34 5.62e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9918079 0.506 rs7696127 chr4:15642953 T/A cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.86 -0.3 1.09e-8 Obesity-related traits; LIHC cis rs4319547 0.695 rs4758666 chr12:122902840 C/T cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.16 -0.36 4.93e-12 Body mass index; LIHC cis rs751728 1.000 rs3806108 chr6:33767579 C/G cg25922239 chr6:33757077 LEMD2 0.43 7.36 0.37 1.34e-12 Crohn's disease; LIHC cis rs9911578 1.000 rs391370 chr17:56675050 A/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs10207060 1.000 rs10207060 chr2:240687289 A/C cg07506560 chr2:240697449 NA 0.55 9.05 0.44 1.06e-17 Obesity-related traits; LIHC cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg22800045 chr5:56110881 MAP3K1 0.69 8.66 0.42 1.89e-16 Initial pursuit acceleration; LIHC cis rs13161895 1.000 rs6873994 chr5:179436696 T/G cg06664874 chr5:179499304 RNF130 -0.58 -7.13 -0.36 5.93e-12 LDL cholesterol; LIHC cis rs4728302 0.869 rs6966403 chr7:133614421 A/C cg10665199 chr7:133106180 EXOC4 -0.37 -6.55 -0.33 2.11e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs4820539 1.000 rs4820539 chr22:23477970 C/T cg14186256 chr22:23484241 RTDR1 -0.9 -18.2 -0.7 3e-52 Bone mineral density; LIHC cis rs6788895 1.000 rs73008903 chr3:150465053 C/T cg09723797 chr3:150481914 SIAH2 0.87 12.1 0.55 2.6e-28 Breast cancer; LIHC cis rs7208859 0.623 rs7220289 chr17:29103762 G/T cg13385521 chr17:29058706 SUZ12P 0.82 8.1 0.4 9.55e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6963495 0.818 rs73192113 chr7:105169603 C/T cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs1008375 0.898 rs9998130 chr4:17593905 A/G cg02297831 chr4:17616191 MED28 0.43 5.92 0.3 7.84e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6061231 0.571 rs482010 chr20:60927551 A/G cg03945807 chr20:60948434 NA -0.38 -6.9 -0.35 2.49e-11 Colorectal cancer; LIHC cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg00166722 chr3:10149974 C3orf24 0.53 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC cis rs12291225 0.637 rs8570 chr11:14300759 C/G cg19336497 chr11:14380999 RRAS2 -0.65 -12.83 -0.57 4.77e-31 Sense of smell; LIHC cis rs3768617 0.811 rs10911232 chr1:183052533 C/T ch.1.3577855R chr1:183094577 LAMC1 0.46 7.43 0.37 8.87e-13 Fuchs's corneal dystrophy; LIHC cis rs17106184 1.000 rs76852824 chr1:51121526 T/C cg07174182 chr1:51127561 FAF1 -0.73 -7.81 -0.39 7.23e-14 Type 2 diabetes; LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg19500275 chr17:80737654 TBCD 0.52 7.61 0.38 2.73e-13 Glycated hemoglobin levels; LIHC cis rs6754311 0.593 rs10195620 chr2:136495619 A/T cg15123519 chr2:136567270 LCT 0.45 8.91 0.43 3.1e-17 Mosquito bite size; LIHC trans rs7618501 0.633 rs2526751 chr3:50064867 T/C cg21659725 chr3:3221576 CRBN -0.69 -11.27 -0.52 2.87e-25 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.917 rs4098044 chr6:86462066 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.95 -0.31 6.73e-9 Response to antipsychotic treatment; LIHC cis rs2737618 0.680 rs2737686 chr1:200094347 C/T cg21825944 chr1:200113062 NR5A2 -0.4 -6.49 -0.33 3.08e-10 Uric acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15356780 chr14:90422831 TDP1 0.45 6.2 0.32 1.59e-9 Pancreatic cancer; LIHC cis rs6545883 0.894 rs6709441 chr2:61436930 A/T cg14146966 chr2:61757674 XPO1 -0.42 -6.89 -0.35 2.75e-11 Tuberculosis; LIHC cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg02951883 chr7:2050386 MAD1L1 -0.59 -8.97 -0.44 2.03e-17 Bipolar disorder and schizophrenia; LIHC cis rs7131987 0.683 rs12366505 chr12:29474110 C/T cg12903224 chr12:29470962 FAR2 -0.41 -6.65 -0.34 1.14e-10 QT interval; LIHC cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg06634786 chr22:41940651 POLR3H -0.82 -8.76 -0.43 9.32e-17 Vitiligo; LIHC cis rs4908768 0.657 rs12144099 chr1:8816175 G/A cg20416874 chr1:8611966 RERE 0.45 6.47 0.33 3.37e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs17376456 0.877 rs10476599 chr5:93383423 A/G cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs4638749 0.677 rs7570544 chr2:108848137 C/T cg25838818 chr2:108905173 SULT1C2 -0.38 -6.84 -0.35 3.61e-11 Blood pressure; LIHC cis rs59901009 0.871 rs12280624 chr11:10206666 T/G cg01453529 chr11:10209919 SBF2 -0.35 -6.69 -0.34 9.37e-11 Hematocrit;Hemoglobin concentration; LIHC cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.14 0.44 5.5e-18 Electroencephalogram traits; LIHC cis rs2153535 0.580 rs4960411 chr6:8438231 C/G cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.3e-16 Motion sickness; LIHC cis rs1555322 0.530 rs2425043 chr20:33868702 T/C cg07134254 chr20:33865797 NA 0.52 6.24 0.32 1.3e-9 Attention deficit hyperactivity disorder; LIHC cis rs10916814 0.632 rs6701759 chr1:20898400 G/T cg24502330 chr1:20914028 CDA -0.3 -6.63 -0.34 1.34e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7208859 0.623 rs73269988 chr17:29118145 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8081395 0.899 rs2777898 chr17:57815608 G/C cg13753209 chr17:57696993 CLTC -0.48 -7.3 -0.37 2e-12 White blood cell count; LIHC cis rs7208859 0.623 rs1054397 chr17:29110196 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4718428 0.672 rs4718412 chr7:66286867 C/T cg12165864 chr7:66369176 NA 0.47 6.85 0.35 3.38e-11 Corneal structure; LIHC cis rs9611565 0.512 rs139562 chr22:42196684 G/C cg06634786 chr22:41940651 POLR3H -0.75 -7.8 -0.39 7.39e-14 Vitiligo; LIHC cis rs2303745 0.544 rs6512181 chr19:17399213 T/G cg02221750 chr19:17393354 ANKLE1 -0.41 -5.8 -0.3 1.53e-8 Systemic lupus erythematosus; LIHC cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg22029157 chr1:209979665 IRF6 0.51 8.31 0.41 2.2e-15 Cleft lip with or without cleft palate; LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.87 0.39 4.61e-14 Prudent dietary pattern; LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg12064134 chr16:90016061 DEF8 -0.44 -5.97 -0.31 5.99e-9 Skin colour saturation; LIHC cis rs2273669 0.667 rs116189763 chr6:109302894 T/C cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg05665937 chr4:1216051 CTBP1 0.46 6.07 0.31 3.48e-9 Obesity-related traits; LIHC cis rs12620999 1.000 rs28727919 chr2:238003313 C/T cg23555395 chr2:238036564 NA 0.31 5.76 0.3 1.92e-8 Systemic lupus erythematosus; LIHC cis rs9486715 0.964 rs6921480 chr6:97066329 C/G cg06623918 chr6:96969491 KIAA0776 -0.84 -13.77 -0.6 1.21e-34 Headache; LIHC cis rs12744310 0.887 rs36040148 chr1:41801448 T/C cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9916302 0.904 rs11655531 chr17:37697959 T/C cg00129232 chr17:37814104 STARD3 -0.42 -6.75 -0.34 6.42e-11 Glomerular filtration rate (creatinine); LIHC cis rs5769765 1.000 rs768618 chr22:50286827 G/A cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.25e-16 Schizophrenia; LIHC cis rs2760061 0.626 rs2313118 chr1:228118084 T/C cg02753203 chr1:228287806 NA -0.49 -7.61 -0.38 2.71e-13 Diastolic blood pressure; LIHC cis rs8084351 0.599 rs12454839 chr18:50678200 A/G cg24270629 chr18:50823537 DCC -0.44 -6.67 -0.34 1.05e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs6964587 1.000 rs10270598 chr7:91700827 T/C cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs12477438 0.834 rs11903311 chr2:99701807 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -9.08 -0.44 8.53e-18 Chronic sinus infection; LIHC cis rs4727027 0.865 rs13236754 chr7:148845773 G/A cg23583168 chr7:148888333 NA -0.74 -10.5 -0.49 1.55e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs17253792 0.822 rs75763956 chr14:56071176 A/G cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs600806 0.713 rs11102984 chr1:109997373 T/C cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.32 -0.32 8.08e-10 Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03104356 chr8:30013879 DCTN6 -0.53 -6.18 -0.32 1.8e-9 Systolic blood pressure; LIHC cis rs4794202 0.534 rs6503875 chr17:45915395 T/C cg10638573 chr17:45915098 SCRN2 0.58 5.84 0.3 1.22e-8 Alzheimer's disease (cognitive decline); LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg26338869 chr17:61819248 STRADA 0.52 6.81 0.35 4.41e-11 Height; LIHC cis rs9902453 0.817 rs2729435 chr17:28121532 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.73 -12.06 -0.55 3.78e-28 Coffee consumption (cups per day); LIHC cis rs875971 0.830 rs809025 chr7:65849819 C/G cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg19635926 chr16:89946313 TCF25 0.49 6.89 0.35 2.67e-11 Skin colour saturation; LIHC trans rs78049276 0.688 rs61075980 chr4:148374767 G/A cg13149281 chr14:23389818 RBM23;PRMT5 -0.62 -7.61 -0.38 2.72e-13 Pulse pressure; LIHC cis rs62380364 0.613 rs254781 chr5:88000636 C/T cg22951263 chr5:87985283 NA -0.41 -7.21 -0.36 3.69e-12 Intelligence (multi-trait analysis); LIHC trans rs3780486 0.718 rs73645257 chr9:33132354 C/T cg20290983 chr6:43655470 MRPS18A 0.95 14.46 0.62 2.57e-37 IgG glycosylation; LIHC cis rs7715806 0.500 rs17563610 chr5:74981322 A/T cg19683494 chr5:74908142 NA 0.69 7.93 0.39 3.21e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2952156 0.920 rs1565920 chr17:37831613 G/A cg00129232 chr17:37814104 STARD3 -0.55 -10.34 -0.49 5.63e-22 Asthma; LIHC cis rs6815814 0.898 rs1106956 chr4:38889811 A/G cg06935464 chr4:38784597 TLR10 0.44 6.79 0.34 4.93e-11 Breast cancer; LIHC cis rs1577917 0.655 rs6454472 chr6:86224053 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.44 8.05 0.4 1.38e-14 Response to antipsychotic treatment; LIHC cis rs600806 0.821 rs3879447 chr1:109891403 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.21 -0.32 1.53e-9 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs7433663 chr3:134235790 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs8073060 0.586 rs7217533 chr17:34015876 A/G cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7659604 0.539 rs2221628 chr4:122795361 G/A cg20573242 chr4:122745356 CCNA2 0.53 7.85 0.39 5.49e-14 Type 2 diabetes; LIHC cis rs77637988 0.553 rs10169629 chr2:48625044 G/T cg15846641 chr2:48541264 FOXN2 0.53 7.11 0.36 6.65e-12 Joint mobility (Beighton score); LIHC cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg08888203 chr3:10149979 C3orf24 0.59 6.93 0.35 2.13e-11 Alzheimer's disease; LIHC cis rs9326248 0.861 rs4938353 chr11:117046197 G/A cg11861562 chr11:117069780 TAGLN 0.37 5.89 0.3 9.14e-9 Blood protein levels; LIHC cis rs3770081 1.000 rs3770087 chr2:86267068 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -9.48 -0.46 4.51e-19 Facial emotion recognition (sad faces); LIHC cis rs4970988 0.787 rs1532770 chr1:150725335 G/T cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.15e-9 Urate levels; LIHC cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg13393036 chr8:95962371 TP53INP1 -0.42 -10.0 -0.48 7.96e-21 Type 2 diabetes; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17652741 chr4:13629432 BOD1L -0.55 -6.47 -0.33 3.4e-10 Systolic blood pressure; LIHC cis rs12477438 0.677 rs12475034 chr2:99699464 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.75 -8.44 -0.41 9.42e-16 Chronic sinus infection; LIHC cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg15691649 chr6:25882328 NA 0.49 7.33 0.37 1.62e-12 Blood metabolite levels; LIHC cis rs12477438 0.798 rs1349778 chr2:99645011 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.82 -10.47 -0.49 1.95e-22 Chronic sinus infection; LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg08677398 chr8:58056175 NA 0.41 6.38 0.33 5.63e-10 Developmental language disorder (linguistic errors); LIHC cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg27170947 chr2:26402098 FAM59B -0.69 -8.46 -0.42 7.82e-16 Gut microbiome composition (summer); LIHC cis rs765787 0.530 rs1648285 chr15:45517505 C/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.41 -0.37 9.74e-13 Uric acid levels; LIHC cis rs9916302 0.904 rs12600751 chr17:37553651 G/C cg07936489 chr17:37558343 FBXL20 0.82 13.01 0.58 9.92e-32 Glomerular filtration rate (creatinine); LIHC cis rs9457247 0.624 rs9457260 chr6:167466665 C/T cg12798992 chr6:167411361 FGFR1OP 0.45 6.78 0.34 5.45e-11 Crohn's disease; LIHC cis rs1005277 0.579 rs2505194 chr10:38393881 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.79 -0.3 1.61e-8 Extrinsic epigenetic age acceleration; LIHC trans rs73389468 1 rs73389468 chr10:134295815 C/T cg23567800 chr14:96064341 NA -0.63 -6.06 -0.31 3.56e-9 Periodontitis (CDC/AAP); LIHC cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg17554472 chr22:41940697 POLR3H 0.54 5.9 0.3 8.82e-9 Vitiligo; LIHC cis rs11098699 0.848 rs4538492 chr4:124113609 A/G cg09941581 chr4:124220074 SPATA5 0.31 5.77 0.3 1.82e-8 Mosquito bite size; LIHC cis rs177542 1 rs177542 chr11:16922654 G/A cg05701403 chr11:16947551 PLEKHA7 0.45 7.17 0.36 4.63e-12 Diastolic blood pressure; LIHC cis rs798554 1.000 rs798560 chr7:2758309 A/G cg19717773 chr7:2847554 GNA12 -0.4 -6.31 -0.32 8.68e-10 Height; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00875911 chr4:1224246 CTBP1 0.45 6.34 0.32 7.46e-10 Bilirubin levels; LIHC cis rs1144333 1.000 rs12078893 chr1:76370862 T/C cg10523679 chr1:76189770 ACADM 0.45 6.52 0.33 2.58e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs3740540 0.761 rs61870251 chr10:126284415 A/C cg20435097 chr10:126320824 FAM53B 0.54 8.0 0.4 2e-14 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC trans rs116095464 0.558 rs10057299 chr5:242135 C/T cg00938859 chr5:1591904 SDHAP3 0.57 7.07 0.36 8.57e-12 Breast cancer; LIHC cis rs7085104 0.700 rs3740397 chr10:104592675 G/C cg15744005 chr10:104629667 AS3MT -0.36 -7.69 -0.38 1.61e-13 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs4907240 0.961 rs12471390 chr2:97322958 C/T cg26665480 chr2:98280029 ACTR1B -0.41 -6.02 -0.31 4.52e-9 Event-related brain oscillations; LIHC cis rs6543140 0.929 rs11465700 chr2:103057668 G/A cg09003973 chr2:102972529 NA 0.52 5.83 0.3 1.31e-8 Blood protein levels; LIHC cis rs1707322 0.752 rs28623463 chr1:46170758 A/C cg03146154 chr1:46216737 IPP 0.58 9.45 0.45 5.66e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg15691649 chr6:25882328 NA -0.53 -7.62 -0.38 2.55e-13 Blood metabolite levels; LIHC cis rs67981189 0.593 rs7147862 chr14:71438202 T/A cg15816911 chr14:71606274 NA -0.4 -6.44 -0.33 4.15e-10 Schizophrenia; LIHC cis rs611744 0.806 rs2440387 chr8:109067078 A/G cg21045802 chr8:109455806 TTC35 0.47 8.02 0.4 1.71e-14 Dupuytren's disease; LIHC cis rs67311347 1.000 rs7648952 chr3:40457038 C/T cg24209194 chr3:40518798 ZNF619 -0.48 -7.11 -0.36 6.88e-12 Renal cell carcinoma; LIHC cis rs6782228 0.675 rs2253151 chr3:128330137 T/C cg16766828 chr3:128327626 NA -0.43 -6.88 -0.35 2.93e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs9611565 0.568 rs5751159 chr22:42175365 G/A cg06634786 chr22:41940651 POLR3H 0.54 5.8 0.3 1.47e-8 Vitiligo; LIHC cis rs2153535 0.601 rs969420 chr6:8451966 T/A cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC trans rs877282 0.945 rs11253391 chr10:788752 G/A cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs875971 0.660 rs6460308 chr7:66084740 T/C cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.48e-14 Aortic root size; LIHC cis rs4665809 0.590 rs13019536 chr2:26526978 C/A cg26119090 chr2:26468346 HADHA;HADHB -0.69 -9.74 -0.47 6.27e-20 Gut microbiome composition (summer); LIHC cis rs1355223 0.902 rs704744 chr11:34736561 A/G cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg07133347 chr1:107600762 PRMT6 0.44 6.71 0.34 8.09e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs801193 1.000 rs7785213 chr7:66138978 A/C cg14393609 chr7:65229607 NA -0.37 -5.85 -0.3 1.18e-8 Aortic root size; LIHC cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg06634786 chr22:41940651 POLR3H -0.79 -8.66 -0.42 1.96e-16 Vitiligo; LIHC cis rs7944735 0.508 rs9666924 chr11:47540007 C/T cg20307385 chr11:47447363 PSMC3 0.59 6.96 0.35 1.75e-11 Intraocular pressure; LIHC cis rs804280 0.565 rs1466785 chr8:11623456 C/T cg12395012 chr8:11607386 GATA4 -0.42 -7.1 -0.36 7.46e-12 Myopia (pathological); LIHC cis rs7572733 0.515 rs1401096 chr2:198823828 A/G cg00792783 chr2:198669748 PLCL1 0.46 6.79 0.34 5.03e-11 Dermatomyositis; LIHC cis rs709400 0.627 rs62007686 chr14:103899344 A/G cg26031613 chr14:104095156 KLC1 0.78 10.21 0.48 1.54e-21 Body mass index; LIHC cis rs2737618 0.674 rs2816973 chr1:200084743 C/G cg21825944 chr1:200113062 NR5A2 0.41 7.1 0.36 7.35e-12 Uric acid levels; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.04 25.81 0.81 2.67e-82 Prudent dietary pattern; LIHC cis rs13118159 0.801 rs10024996 chr4:1328297 G/A cg13395646 chr4:1353034 KIAA1530 -0.63 -8.66 -0.42 1.87e-16 Longevity; LIHC cis rs2637266 0.756 rs2245335 chr10:78553265 T/C cg18941641 chr10:78392320 NA 0.28 6.01 0.31 4.85e-9 Pulmonary function; LIHC cis rs9916302 0.851 rs11870631 chr17:37645129 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07208322 chr5:177027175 B4GALT7 -0.45 -6.2 -0.32 1.6e-9 Pancreatic cancer; LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg06951627 chr6:26196580 NA 0.55 6.43 0.33 4.39e-10 Gout;Renal underexcretion gout; LIHC cis rs7044106 0.762 rs1470307 chr9:123433039 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.05 0.51 1.77e-24 Hip circumference adjusted for BMI; LIHC cis rs9811920 0.555 rs68092024 chr3:99691522 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 6.52 0.33 2.46e-10 Axial length; LIHC cis rs7617773 0.709 rs4404473 chr3:48353626 A/G cg11946769 chr3:48343235 NME6 0.9 11.15 0.52 7.54e-25 Coronary artery disease; LIHC cis rs4820539 1.000 rs5759596 chr22:23475750 G/A cg14186256 chr22:23484241 RTDR1 0.97 21.1 0.75 6.91e-64 Bone mineral density; LIHC cis rs10078 0.515 rs1053299 chr5:470760 G/A cg24955955 chr5:415729 AHRR 0.6 11.32 0.52 1.94e-25 Fat distribution (HIV); LIHC cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg03351412 chr1:154909251 PMVK 0.7 10.33 0.49 6.04e-22 Prostate cancer; LIHC cis rs6951245 0.938 rs11764937 chr7:1092074 C/T cg24642844 chr7:1081250 C7orf50 -0.96 -9.45 -0.46 5.34e-19 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.99 9.32 0.45 1.46e-18 Platelet count; LIHC cis rs2841277 0.616 rs1048257 chr14:105404384 T/C cg15352829 chr14:105391018 PLD4 -0.43 -9.22 -0.45 3.04e-18 Rheumatoid arthritis; LIHC cis rs888194 0.738 rs2241213 chr12:109938857 A/G cg05360138 chr12:110035743 NA 0.4 5.74 0.3 2.07e-8 Neuroticism; LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg18279126 chr7:2041391 MAD1L1 -0.39 -6.67 -0.34 1.06e-10 Bipolar disorder and schizophrenia; LIHC trans rs7937890 0.559 rs6486193 chr11:14437607 C/G cg12999362 chr7:75947528 NA -0.39 -6.88 -0.35 2.79e-11 Mitochondrial DNA levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02667081 chr16:71880439 ATXN1L 0.48 6.93 0.35 2.12e-11 Pancreatic cancer; LIHC cis rs12493885 0.818 rs73158489 chr3:153757862 C/T cg10247383 chr3:153839028 SGEF 0.61 5.78 0.3 1.65e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs10916814 0.632 rs7545313 chr1:20902728 C/T cg24502330 chr1:20914028 CDA -0.31 -6.81 -0.35 4.35e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC trans rs3758911 0.765 rs687991 chr11:107320644 G/C cg21068293 chr15:74496576 STRA6 -0.26 -6.05 -0.31 3.73e-9 Coronary artery disease; LIHC cis rs10832963 1.000 rs4757676 chr11:18640477 C/T cg09201001 chr11:18656081 SPTY2D1 0.94 17.6 0.69 7.83e-50 Breast cancer; LIHC cis rs758324 0.947 rs28537859 chr5:131237277 C/G cg06307176 chr5:131281290 NA -0.41 -5.88 -0.3 9.87e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs8141529 0.748 rs6519766 chr22:29269991 A/G cg15103426 chr22:29168792 CCDC117 -0.57 -9.22 -0.45 3.2e-18 Lymphocyte counts; LIHC cis rs6456156 0.586 rs6909180 chr6:167460537 A/G cg12798992 chr6:167411361 FGFR1OP 0.43 6.73 0.34 7.25e-11 Primary biliary cholangitis; LIHC cis rs3096299 0.503 rs9925045 chr16:89556476 T/C cg02034447 chr16:89574710 SPG7 0.49 7.48 0.38 6.24e-13 Multiple myeloma (IgH translocation); LIHC cis rs13161895 1.000 rs34603792 chr5:179459287 A/G cg02702477 chr5:179499311 RNF130 0.75 10.44 0.49 2.46e-22 LDL cholesterol; LIHC cis rs875971 0.862 rs3926380 chr7:66080645 G/T cg11764359 chr7:65958608 NA -0.78 -13.64 -0.59 4.13e-34 Aortic root size; LIHC cis rs1552244 0.572 rs6442154 chr3:10168785 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -10.89 -0.51 6.57e-24 Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26072851 chr17:56296444 MKS1 0.47 6.2 0.32 1.65e-9 Lung function (FEV1/FVC); LIHC cis rs694739 0.536 rs671976 chr11:64046029 G/A cg05555928 chr11:63887634 MACROD1 -0.39 -6.48 -0.33 3.12e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs8062405 0.789 rs1968752 chr16:28631585 G/T cg00204512 chr16:28754710 NA 0.36 6.12 0.31 2.5e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7613875 0.654 rs3774751 chr3:50209053 G/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.48 -6.42 -0.33 4.64e-10 Body mass index; LIHC cis rs6748734 1.000 rs4675868 chr2:241828542 A/C cg20140201 chr2:241835670 C2orf54 -0.47 -6.45 -0.33 3.9e-10 Urinary metabolites; LIHC cis rs2777491 0.957 rs316614 chr15:41746625 A/G cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.24 -0.45 2.77e-18 Ulcerative colitis; LIHC cis rs67478160 0.643 rs12880167 chr14:104300829 C/T cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.23 -0.36 3.21e-12 Schizophrenia; LIHC cis rs12744310 0.887 rs12048805 chr1:41814276 G/A cg03962019 chr1:41807865 NA 0.38 6.1 0.31 2.84e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6964587 0.934 rs73226382 chr7:91692760 T/C cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24950336 chr3:113464879 ATP6V1A;NAA50 0.45 6.03 0.31 4.15e-9 Lung function (FEV1/FVC); LIHC trans rs4650994 1.000 rs4511075 chr1:178518636 G/A cg05059571 chr16:84539110 KIAA1609 -0.39 -6.49 -0.33 2.94e-10 HDL cholesterol levels;HDL cholesterol; LIHC trans rs2749592 0.513 rs1208708 chr10:38085576 A/G cg18107078 chr1:162760321 HSD17B7 -0.42 -6.59 -0.34 1.66e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10508774 1.000 rs11008971 chr10:32835791 T/C cg01819863 chr10:32635814 EPC1 0.65 6.06 0.31 3.66e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6598955 0.694 rs4659416 chr1:26580937 T/G cg00852783 chr1:26633632 UBXN11 0.5 8.43 0.41 9.56e-16 Obesity-related traits; LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg26354017 chr1:205819088 PM20D1 0.77 11.48 0.53 5.13e-26 Menarche (age at onset); LIHC cis rs7707921 0.646 rs226208 chr5:81603444 G/A cg15871215 chr5:81402204 ATG10 0.64 7.69 0.38 1.5700000000000001e-13 Breast cancer; LIHC trans rs2749592 0.550 rs7917262 chr10:37874602 A/C cg23533926 chr12:111358616 MYL2 0.31 6.05 0.31 3.88e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7223966 1.000 rs8073373 chr17:61703320 T/C cg05941027 chr17:61774174 LIMD2 0.31 6.34 0.32 7.07e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2073300 1.000 rs6114098 chr20:23444276 G/A cg16736954 chr20:23401023 NAPB 0.52 5.84 0.3 1.19e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2739330 0.828 rs5751770 chr22:24252842 A/G cg06437703 chr8:37914619 EIF4EBP1 -0.48 -7.39 -0.37 1.11e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6121246 0.567 rs6120815 chr20:30184866 T/C cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs2153535 0.580 rs9505450 chr6:8469902 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.72 0.39 1.27e-13 Bipolar disorder; LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg14893161 chr1:205819251 PM20D1 0.81 12.08 0.55 3.12e-28 Menarche (age at onset); LIHC cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg09323728 chr8:95962352 TP53INP1 -0.31 -6.93 -0.35 2.11e-11 Type 2 diabetes; LIHC cis rs7772486 0.754 rs697055 chr6:146003790 C/G cg13319975 chr6:146136371 FBXO30 -0.42 -6.72 -0.34 7.65e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7914558 0.966 rs10748839 chr10:104953547 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.74 -0.43 1.08e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs55823223 0.564 rs1463485 chr17:73851791 C/G cg10935138 chr17:73851978 WBP2 0.69 9.12 0.44 6.52e-18 Psoriasis; LIHC trans rs494453 0.922 rs569504 chr1:112211777 A/G cg13655586 chr7:111202389 IMMP2L -0.45 -6.07 -0.31 3.49e-9 Osteoporosis-related phenotypes; LIHC cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -10.09 -0.48 3.92e-21 Platelet count; LIHC cis rs7552404 1.000 rs2133134 chr1:76179587 G/A cg22875332 chr1:76189707 ACADM 0.47 6.72 0.34 7.75e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs17106184 0.551 rs4926859 chr1:50842123 A/T cg07174182 chr1:51127561 FAF1 0.42 5.81 0.3 1.47e-8 Type 2 diabetes; LIHC cis rs1707322 0.717 rs3014246 chr1:46086077 C/T cg03146154 chr1:46216737 IPP -0.55 -9.2 -0.45 3.59e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs921968 0.565 rs1078803 chr2:219606538 A/C cg02985541 chr2:219472218 PLCD4 0.36 6.3 0.32 9.04e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2066819 1.000 rs2643623 chr12:56689725 G/C cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Psoriasis vulgaris; LIHC cis rs7674212 0.541 rs2720448 chr4:104030589 C/T cg16532752 chr4:104119610 CENPE -0.44 -6.89 -0.35 2.67e-11 Type 2 diabetes; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg02820958 chr19:7099040 NA -0.49 -6.09 -0.31 2.98e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1144333 1.000 rs1586936 chr1:76366877 T/C cg03433033 chr1:76189801 ACADM 0.54 8.06 0.4 1.26e-14 Attention function in attention deficit hyperactive disorder; LIHC cis rs35110281 0.720 rs162400 chr21:44950305 A/C cg21573476 chr21:45109991 RRP1B -0.57 -10.34 -0.49 5.55e-22 Mean corpuscular volume; LIHC cis rs2228479 0.850 rs62054599 chr16:89808850 C/G cg19635926 chr16:89946313 TCF25 0.49 6.24 0.32 1.28e-9 Skin colour saturation; LIHC cis rs6547741 1.000 rs1919125 chr2:27801403 C/G cg27432699 chr2:27873401 GPN1 0.72 11.74 0.54 5.55e-27 Oral cavity cancer; LIHC cis rs888194 0.738 rs2241212 chr12:109939641 T/A cg05360138 chr12:110035743 NA 0.41 5.71 0.3 2.41e-8 Neuroticism; LIHC cis rs929354 0.742 rs10274687 chr7:156933181 T/G cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs80282103 0.764 rs12247818 chr10:1110464 G/A cg08668510 chr10:1095578 IDI1 0.65 6.32 0.32 8.19e-10 Glomerular filtration rate (creatinine); LIHC cis rs904251 0.561 rs1757189 chr6:37483727 G/C cg01843034 chr6:37503916 NA -0.46 -7.84 -0.39 5.95e-14 Cognitive performance; LIHC cis rs9457247 0.544 rs6920858 chr6:167464630 G/A cg12798992 chr6:167411361 FGFR1OP 0.45 6.75 0.34 6.53e-11 Crohn's disease; LIHC cis rs12200782 0.505 rs1535275 chr6:26520767 G/C cg09904177 chr6:26538194 HMGN4 0.5 7.05 0.36 1.02e-11 Small cell lung carcinoma; LIHC cis rs1707322 1.000 rs7531911 chr1:46330423 A/G cg03146154 chr1:46216737 IPP 0.47 7.5 0.38 5.65e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs887797 0.557 rs9900353 chr17:64575492 A/G cg27019712 chr17:64599478 PRKCA 0.35 6.11 0.31 2.7e-9 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC cis rs963731 0.649 rs297141 chr2:39319382 T/C cg04010122 chr2:39346883 SOS1 -0.68 -5.95 -0.31 6.6e-9 Corticobasal degeneration; LIHC trans rs9951602 0.512 rs61021837 chr18:76648210 A/C cg02800362 chr5:177631904 HNRNPAB 0.67 10.48 0.49 1.76e-22 Obesity-related traits; LIHC cis rs45544231 0.544 rs7193453 chr16:52565150 C/T cg09051775 chr16:52580266 TOX3 -0.32 -5.88 -0.3 9.89e-9 Restless legs syndrome; LIHC cis rs9549367 0.789 rs12584981 chr13:113881185 T/C cg18105134 chr13:113819100 PROZ -0.67 -11.66 -0.53 1.09e-26 Platelet distribution width; LIHC cis rs9372253 0.678 rs9372251 chr6:110700656 A/G cg01119278 chr6:110721349 DDO -0.32 -6.72 -0.34 7.83e-11 Platelet distribution width; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg09263875 chr16:632152 PIGQ 0.6 11.14 0.52 8.81e-25 Height; LIHC trans rs11165623 0.564 rs7523597 chr1:97000989 A/G cg10631902 chr5:14652156 NA -0.29 -6.81 -0.35 4.31e-11 Hip circumference;Waist circumference; LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg02290350 chr8:58132656 NA 0.51 10.66 0.5 4.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg07424592 chr7:64974309 NA -0.79 -9.39 -0.45 8.91e-19 Diabetic kidney disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21243150 chr15:40751171 BAHD1 0.49 6.05 0.31 3.87e-9 Systolic blood pressure; LIHC cis rs1355223 0.583 rs1828298 chr11:34870439 A/G cg24088639 chr11:34937564 PDHX;APIP -0.39 -5.99 -0.31 5.17e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11671005 0.735 rs1122955 chr19:58946203 C/T cg25952890 chr19:58913133 NA 0.7 7.64 0.38 2.23e-13 Mean platelet volume; LIHC cis rs2251381 0.722 rs2776252 chr21:30531705 G/A cg24692254 chr21:30365293 RNF160 0.71 10.28 0.49 9.07e-22 Selective IgA deficiency; LIHC cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg16145915 chr7:1198662 ZFAND2A -0.38 -9.6 -0.46 1.72e-19 Longevity;Endometriosis; LIHC cis rs9733 0.791 rs11800059 chr1:150651175 C/T cg17724175 chr1:150552817 MCL1 -0.37 -7.7 -0.38 1.45e-13 Tonsillectomy; LIHC cis rs5769765 0.865 rs9616369 chr22:50304591 A/C cg02269571 chr22:50332266 NA -0.61 -8.66 -0.42 1.89e-16 Schizophrenia; LIHC cis rs2274273 0.934 rs17740741 chr14:55762712 G/C cg01864836 chr14:55583639 NA -0.37 -6.46 -0.33 3.52e-10 Protein biomarker; LIHC cis rs2033711 0.755 rs4801587 chr19:58936679 C/A cg00825309 chr19:58991885 ZNF446 -0.63 -9.63 -0.46 1.4e-19 Uric acid clearance; LIHC cis rs3768617 0.510 rs10752903 chr1:183100863 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg01765077 chr12:122356316 WDR66 0.55 7.76 0.39 9.79e-14 Mean corpuscular volume; LIHC trans rs2727020 0.575 rs10769587 chr11:49549849 C/G cg03929089 chr4:120376271 NA -0.88 -16.75 -0.67 2e-46 Coronary artery disease; LIHC cis rs6964587 0.732 rs12539523 chr7:91710836 G/A cg17063962 chr7:91808500 NA 1.01 19.16 0.72 4.17e-56 Breast cancer; LIHC cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.68 0.34 9.43e-11 Bipolar disorder; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.24 0.81 4.27e-80 Prudent dietary pattern; LIHC cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg03806693 chr22:41940476 POLR3H -1.14 -13.54 -0.59 9.67e-34 Vitiligo; LIHC cis rs875971 0.571 rs78668714 chr7:65939451 G/A cg11764359 chr7:65958608 NA 0.59 8.21 0.41 4.58e-15 Aortic root size; LIHC cis rs10751667 0.666 rs11246358 chr11:967349 G/A cg10932868 chr11:921992 NA 0.39 7.38 0.37 1.23e-12 Alzheimer's disease (late onset); LIHC cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg02187348 chr16:89574699 SPG7 0.62 10.08 0.48 4.3e-21 Multiple myeloma (IgH translocation); LIHC cis rs7246657 0.943 rs35540940 chr19:38008235 G/A cg23950597 chr19:37808831 NA -0.46 -5.75 -0.3 1.95e-8 Coronary artery calcification; LIHC cis rs597539 0.652 rs514833 chr11:68657734 C/T cg04772025 chr11:68637568 NA 0.47 6.26 0.32 1.12e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs10892173 0.678 rs4537790 chr11:117661356 A/G cg17419623 chr1:186649559 PTGS2 -0.31 -6.11 -0.31 2.7e-9 Myopia; LIHC cis rs9783347 0.961 rs12293544 chr11:18348581 T/C cg15585147 chr11:18324498 HPS5 0.43 6.73 0.34 6.95e-11 Pancreatic cancer; LIHC cis rs28647808 0.881 rs28494844 chr9:136266188 T/C cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC trans rs3858145 0.588 rs61854831 chr10:70035837 C/T cg04882175 chr6:131122610 NA -0.48 -6.05 -0.31 3.7e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs9814567 1.000 rs6800862 chr3:134228628 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.48 0.38 6.15e-13 Bipolar disorder; LIHC cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg15691649 chr6:25882328 NA -0.83 -12.12 -0.55 2.31e-28 Blood metabolite levels; LIHC cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg12311346 chr5:56204834 C5orf35 -0.56 -7.33 -0.37 1.68e-12 Initial pursuit acceleration; LIHC cis rs758324 0.947 rs2896961 chr5:131165006 C/T cg06307176 chr5:131281290 NA 0.42 6.09 0.31 3.04e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.56 -7.8 -0.39 7.73e-14 Lymphocyte counts; LIHC cis rs12477438 0.501 rs11685756 chr2:99766215 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.21 21.25 0.75 1.75e-64 Chronic sinus infection; LIHC cis rs10870270 1.000 rs11146354 chr10:133774757 A/G cg17892150 chr10:133769511 PPP2R2D -0.68 -12.76 -0.57 9.05e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10197940 0.578 rs2432946 chr2:152306897 G/T cg19508488 chr2:152266495 RIF1 -0.49 -6.97 -0.35 1.65e-11 Lung cancer; LIHC cis rs12477438 0.798 rs2045057 chr2:99684929 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.67 -0.53 1.03e-26 Chronic sinus infection; LIHC cis rs3853824 0.965 rs12103557 chr17:54908131 A/T cg13675837 chr17:54910204 DGKE 0.42 5.91 0.3 8.42e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg02951883 chr7:2050386 MAD1L1 -0.66 -11.11 -0.51 1.11e-24 Bipolar disorder and schizophrenia; LIHC cis rs798554 0.796 rs2158694 chr7:2863443 T/G cg19346786 chr7:2764209 NA -0.46 -6.81 -0.35 4.3e-11 Height; LIHC cis rs9790314 0.905 rs7611367 chr3:161003182 A/G cg03342759 chr3:160939853 NMD3 0.61 7.24 0.36 3.05e-12 Morning vs. evening chronotype; LIHC cis rs11630290 0.592 rs1912049 chr15:64155606 G/T cg12036633 chr15:63758958 NA 0.6 6.38 0.33 5.66e-10 Iris characteristics; LIHC trans rs1814175 0.645 rs1818895 chr11:50031523 G/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs6752107 0.870 rs13418066 chr2:234145944 A/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.51 7.53 0.38 4.47e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1707322 1.000 rs10890382 chr1:46469674 A/G cg03146154 chr1:46216737 IPP 0.47 7.47 0.37 6.54e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg14004847 chr7:1930337 MAD1L1 -0.42 -5.87 -0.3 1.04e-8 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.966 rs13072802 chr3:47346415 G/C cg16586182 chr3:47516702 SCAP -0.54 -9.86 -0.47 2.43e-20 Colorectal cancer; LIHC trans rs637571 0.522 rs7105628 chr11:65763067 C/T cg17712092 chr4:129076599 LARP1B 0.75 13.22 0.58 1.69e-32 Eosinophil percentage of white cells; LIHC cis rs2629540 0.889 rs17624662 chr10:126408146 A/C cg08799069 chr10:126477246 METTL10 0.48 7.56 0.38 3.75e-13 Cocaine dependence; LIHC cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg06634786 chr22:41940651 POLR3H -0.77 -7.75 -0.39 1.09e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs370915 0.963 rs59452206 chr4:187816484 G/T cg19519643 chr4:187840862 NA -0.43 -6.9 -0.35 2.48e-11 Gout; LIHC cis rs2637266 1.000 rs2395388 chr10:78357203 C/T cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs11673344 0.864 rs7259513 chr19:37576704 G/A cg27390819 chr19:37464633 NA -0.51 -6.17 -0.32 1.89e-9 Obesity-related traits; LIHC cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg03806693 chr22:41940476 POLR3H 1.1 12.74 0.57 1.04e-30 Vitiligo; LIHC cis rs12986413 0.651 rs35751290 chr19:2139357 A/G cg09261902 chr19:2140048 AP3D1 0.4 6.78 0.34 5.3e-11 Height; LIHC trans rs1005277 0.579 rs2008449 chr10:38414204 A/T cg17830980 chr10:43048298 ZNF37B 0.53 10.74 0.5 2.25e-23 Extrinsic epigenetic age acceleration; LIHC cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg06212747 chr3:49208901 KLHDC8B 0.63 8.52 0.42 5.08e-16 Menarche (age at onset); LIHC cis rs61990749 0.597 rs3783980 chr14:78219807 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.16 0.48 2.37e-21 Fibroblast growth factor basic levels; LIHC cis rs921968 0.565 rs7573999 chr2:219601392 A/G cg02985541 chr2:219472218 PLCD4 -0.36 -6.3 -0.32 8.95e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7212590 0.748 rs55794618 chr17:57934337 G/C cg10252138 chr17:58120427 NA -0.62 -6.34 -0.32 7.42e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs4631830 0.720 rs11004415 chr10:51498181 G/A cg20129853 chr10:51489980 NA 0.4 8.57 0.42 3.7e-16 Prostate-specific antigen levels; LIHC cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg27170947 chr2:26402098 FAM59B -0.72 -8.67 -0.42 1.7e-16 Gut microbiome composition (summer); LIHC cis rs67478160 0.643 rs8003653 chr14:104298836 A/G cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.41 -0.37 9.85e-13 Schizophrenia; LIHC trans rs1814175 0.817 rs7947286 chr11:49874657 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.15e-11 Height; LIHC cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg13607699 chr17:42295918 UBTF 0.44 7.1 0.36 7.46e-12 Total body bone mineral density; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg24441383 chr12:19459574 PLEKHA5 0.49 6.31 0.32 8.54e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg24531977 chr5:56204891 C5orf35 0.74 10.53 0.49 1.17e-22 Initial pursuit acceleration; LIHC cis rs9309473 0.950 rs6745480 chr2:73840055 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.87 -0.35 2.97e-11 Metabolite levels; LIHC cis rs2016586 0.895 rs2899256 chr22:36114054 C/T cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 7.96e-10 Body mass index; LIHC trans rs528418 0.651 rs77580825 chr6:145543323 G/C cg09173621 chr13:111773936 ARHGEF7 0.52 6.04 0.31 4.03e-9 Methadone dose in opioid dependence; LIHC cis rs2479724 0.755 rs4318867 chr6:41753670 G/T cg17623882 chr6:41773611 USP49 0.55 8.77 0.43 8.44e-17 Menarche (age at onset); LIHC cis rs74233809 1.000 rs11191557 chr10:104864614 C/G cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.43e-9 Birth weight; LIHC cis rs7923452 0.938 rs34560372 chr10:30773831 G/A cg25182066 chr10:30743637 MAP3K8 0.69 9.78 0.47 4.32e-20 Itch intensity from mosquito bite; LIHC cis rs311392 0.554 rs311388 chr8:55101869 T/A cg11783602 chr8:55087084 NA -0.31 -6.23 -0.32 1.37e-9 Pelvic organ prolapse (moderate/severe); LIHC trans rs3783890 1.000 rs11628538 chr14:93746562 G/A cg02802420 chr16:69363236 PDF;COG8 0.32 6.22 0.32 1.44e-9 Body mass index; LIHC cis rs74181299 0.784 rs2723082 chr2:65289623 C/T cg05010058 chr2:65284262 CEP68 0.39 6.65 0.34 1.18e-10 Pulse pressure; LIHC cis rs597539 0.616 rs513476 chr11:68698996 C/T cg04772025 chr11:68637568 NA 0.49 6.35 0.32 6.96e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1707322 0.638 rs9429095 chr1:46603348 A/C cg03146154 chr1:46216737 IPP -0.41 -6.41 -0.33 4.78e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1982963 0.572 rs61971551 chr14:52479975 C/G cg10843707 chr14:52510701 NID2 0.39 5.81 0.3 1.47e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs904251 0.523 rs2776871 chr6:37481759 A/G cg01843034 chr6:37503916 NA -0.48 -8.24 -0.41 3.59e-15 Cognitive performance; LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg07167872 chr1:205819463 PM20D1 0.6 8.72 0.43 1.24e-16 Menarche (age at onset); LIHC cis rs10493773 0.775 rs12756013 chr1:86153532 C/T cg17807903 chr1:86174739 ZNHIT6 -0.56 -10.21 -0.48 1.49e-21 Urate levels in overweight individuals; LIHC cis rs35306767 0.855 rs12781100 chr10:838636 C/T cg26597838 chr10:835615 NA 1.39 15.04 0.63 1.32e-39 Eosinophil percentage of granulocytes; LIHC cis rs7927771 1.000 rs12419692 chr11:47624714 A/C cg18512352 chr11:47633146 NA 0.26 6.17 0.32 1.96e-9 Subjective well-being; LIHC cis rs763014 0.932 rs2384972 chr16:674424 G/A cg04709771 chr16:646395 RAB40C 0.47 8.33 0.41 1.99e-15 Height; LIHC cis rs7618501 1.000 rs60205400 chr3:49800272 C/T cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.34e-11 Intelligence (multi-trait analysis); LIHC cis rs10508774 1.000 rs12414510 chr10:33041698 G/T cg01819863 chr10:32635814 EPC1 0.62 5.72 0.3 2.27e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8072100 0.967 rs4580230 chr17:45738861 G/A cg08085267 chr17:45401833 C17orf57 -0.57 -8.43 -0.41 9.46e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4660306 0.961 rs1494813 chr1:45957290 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.64 -7.61 -0.38 2.7e-13 Homocysteine levels; LIHC cis rs2404602 0.735 rs283789 chr15:76777577 G/A cg23625390 chr15:77176239 SCAPER 0.47 7.78 0.39 8.84e-14 Blood metabolite levels; LIHC cis rs868036 0.718 rs4776982 chr15:68114974 C/T cg24579218 chr15:68104479 NA 0.34 5.78 0.3 1.72e-8 Restless legs syndrome; LIHC cis rs8180040 0.764 rs12629262 chr3:47196580 C/T cg16586182 chr3:47516702 SCAP -0.5 -8.93 -0.43 2.66e-17 Colorectal cancer; LIHC cis rs2050392 1.000 rs2265185 chr10:30691777 A/C cg25182066 chr10:30743637 MAP3K8 -0.44 -7.08 -0.36 8.32e-12 Inflammatory bowel disease; LIHC cis rs858239 0.508 rs7805085 chr7:23190243 C/T cg18081818 chr7:23246105 NA -0.39 -5.75 -0.3 1.95e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs3091242 0.933 rs28530483 chr1:25740847 A/C cg02931644 chr1:25747376 RHCE 0.34 7.54 0.38 4.27e-13 Erythrocyte sedimentation rate; LIHC cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg11062466 chr8:58055876 NA 0.51 7.34 0.37 1.62e-12 Developmental language disorder (linguistic errors); LIHC cis rs6754311 0.773 rs4988183 chr2:136622046 T/C cg25344623 chr2:136566232 LCT -0.34 -6.72 -0.34 7.77e-11 Mosquito bite size; LIHC trans rs801193 0.844 rs7779971 chr7:66161790 T/C cg26939375 chr7:64535504 NA 0.43 6.84 0.35 3.67e-11 Aortic root size; LIHC cis rs7131987 0.617 rs3764953 chr12:29502236 T/C cg00204748 chr12:29376779 FAR2 0.38 6.76 0.34 5.89e-11 QT interval; LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg16255150 chr14:73924775 NUMB -0.88 -7.14 -0.36 5.53e-12 Mild influenza (H1N1) infection; LIHC cis rs6951245 0.580 rs10257426 chr7:1213694 G/A cg18402987 chr7:1209562 NA 0.54 5.82 0.3 1.37e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6952808 0.529 rs73038442 chr7:2139457 C/T cg20295408 chr7:1910781 MAD1L1 -0.41 -5.98 -0.31 5.51e-9 Bipolar disorder and schizophrenia; LIHC cis rs2274273 0.967 rs2340931 chr14:55616937 T/G cg04306507 chr14:55594613 LGALS3 0.32 6.22 0.32 1.46e-9 Protein biomarker; LIHC cis rs2251381 0.750 rs2251087 chr21:30527999 C/T cg24692254 chr21:30365293 RNF160 0.71 10.3 0.49 7.86e-22 Selective IgA deficiency; LIHC cis rs1552244 0.882 rs34779351 chr3:10021801 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC trans rs11098499 0.826 rs4472123 chr4:120236630 T/A cg25214090 chr10:38739885 LOC399744 0.52 8.36 0.41 1.63e-15 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11355319 chr5:89825117 LYSMD3 0.45 6.38 0.33 5.8e-10 Pancreatic cancer; LIHC cis rs7937682 0.632 rs11214015 chr11:111719417 A/T cg09085632 chr11:111637200 PPP2R1B -0.92 -13.71 -0.6 2.05e-34 Primary sclerosing cholangitis; LIHC cis rs10256972 0.616 rs6957733 chr7:1106327 T/G cg07308232 chr7:1071921 C7orf50 -0.44 -6.74 -0.34 6.7e-11 Longevity;Endometriosis; LIHC cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg05665937 chr4:1216051 CTBP1 0.46 6.09 0.31 3.11e-9 Obesity-related traits; LIHC cis rs7224314 1.000 rs62085810 chr17:65372855 G/A cg01507342 chr17:65387096 PITPNC1 -0.47 -5.78 -0.3 1.65e-8 Diisocyanate-induced asthma; LIHC cis rs2073300 1.000 rs6132629 chr20:23451251 G/A cg12062639 chr20:23401060 NAPB 0.81 9.62 0.46 1.56e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24372485 chr19:2078331 MOBKL2A 0.41 6.06 0.31 3.62e-9 Longevity; LIHC cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs655641 1.000 rs488134 chr11:85701622 T/C cg09030501 chr11:85779252 PICALM -0.56 -6.47 -0.33 3.32e-10 Platelet count; LIHC cis rs7903847 0.620 rs61863815 chr10:99124389 A/G cg20016023 chr10:99160130 RRP12 -0.41 -6.34 -0.32 7.3e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs921968 0.528 rs13022583 chr2:219589175 T/C cg02985541 chr2:219472218 PLCD4 -0.38 -6.66 -0.34 1.07e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3020736 0.500 rs7292241 chr22:42492063 G/A cg15557168 chr22:42548783 NA 0.46 7.08 0.36 8.47e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg20607798 chr8:58055168 NA -0.71 -8.14 -0.4 7.65e-15 Developmental language disorder (linguistic errors); LIHC trans rs4342066 0.778 rs1870258 chr3:28390041 G/A cg11103623 chr3:57235255 HESX1 -0.38 -6.13 -0.31 2.44e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs17817600 0.866 rs7107455 chr11:85642444 C/T cg03102841 chr11:85646010 NA 0.44 5.81 0.3 1.47e-8 Alzheimer's disease; LIHC cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg11764359 chr7:65958608 NA 0.57 5.82 0.3 1.39e-8 Diabetic kidney disease; LIHC cis rs2204008 0.592 rs2320501 chr12:38145285 T/G cg13010199 chr12:38710504 ALG10B 0.51 5.84 0.3 1.21e-8 Bladder cancer; LIHC cis rs2976388 0.566 rs2585146 chr8:143798641 A/C cg06565975 chr8:143823917 SLURP1 0.45 7.94 0.39 2.91e-14 Urinary tract infection frequency; LIHC cis rs6582630 0.519 rs7305545 chr12:38349223 G/A cg26384229 chr12:38710491 ALG10B 0.6 8.28 0.41 2.76e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs7772486 0.658 rs4895683 chr6:146113654 T/A cg13319975 chr6:146136371 FBXO30 0.36 5.83 0.3 1.29e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs798554 1.000 rs798560 chr7:2758309 A/G cg19346786 chr7:2764209 NA -0.42 -6.25 -0.32 1.22e-9 Height; LIHC cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg18404041 chr3:52824283 ITIH1 -0.55 -8.94 -0.44 2.53e-17 Bipolar disorder; LIHC trans rs7618501 1.000 rs7374277 chr3:49784777 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.81 -0.63 1.12e-38 Intelligence (multi-trait analysis); LIHC cis rs4730250 0.707 rs4730222 chr7:106810293 G/C cg02696742 chr7:106810147 HBP1 -0.55 -6.29 -0.32 9.84e-10 Osteoarthritis; LIHC cis rs1568889 1.000 rs12797155 chr11:28290866 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 7.05 0.36 9.97e-12 Bipolar disorder; LIHC cis rs61612642 0.590 rs6931028 chr6:42193064 A/T cg01092361 chr6:42185687 MRPS10 0.9 8.91 0.43 2.99e-17 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs2836950 0.501 rs2836985 chr21:40701169 A/G cg11890956 chr21:40555474 PSMG1 -0.45 -7.32 -0.37 1.78e-12 Menarche (age at onset); LIHC cis rs2708977 0.901 rs3731938 chr2:97166204 A/G cg01950434 chr2:97203154 ARID5A -0.5 -7.48 -0.38 6.12e-13 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs1059312 1.000 rs7970815 chr12:129288366 G/A cg09035930 chr12:129282057 SLC15A4 0.68 13.05 0.58 7.41e-32 Systemic lupus erythematosus; LIHC cis rs3793683 1.000 rs3793683 chr10:134568387 G/T cg26818010 chr10:134567672 INPP5A 0.63 8.45 0.42 8.32e-16 Migraine; LIHC cis rs12579753 0.830 rs12825476 chr12:82238350 G/A cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs1355223 0.583 rs2915177 chr11:34880266 A/G cg06937548 chr11:34938143 PDHX;APIP 0.42 5.94 0.31 7.11e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg23758822 chr17:41437982 NA 0.93 17.85 0.69 8.09e-51 Menopause (age at onset); LIHC cis rs2257205 0.667 rs8080281 chr17:56938558 A/G cg05425664 chr17:57184151 TRIM37 0.6 6.7 0.34 8.83e-11 Pancreatic cancer; LIHC cis rs2602836 0.830 rs2602874 chr4:100039396 A/T cg12011299 chr4:100065546 ADH4 0.54 12.68 0.57 1.81e-30 HDL cholesterol;HDL cholesterol levels; LIHC cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.43 -0.45 6.23e-19 Bipolar disorder; LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs7474896 0.537 rs1022449 chr10:38279467 T/A cg25427524 chr10:38739819 LOC399744 0.45 6.0 0.31 4.93e-9 Obesity (extreme); LIHC cis rs35306767 0.761 rs12771539 chr10:1050653 A/G cg20503657 chr10:835505 NA 0.83 7.99 0.4 2.07e-14 Eosinophil percentage of granulocytes; LIHC cis rs9486719 0.947 rs12213375 chr6:96902134 A/G cg06623918 chr6:96969491 KIAA0776 -0.79 -7.43 -0.37 8.51e-13 Migraine;Coronary artery disease; LIHC cis rs4423214 1.000 rs7928249 chr11:71161063 A/G cg05163923 chr11:71159392 DHCR7 0.89 13.73 0.6 1.82e-34 Vitamin D levels; LIHC cis rs7560272 0.723 rs1083919 chr2:73713863 C/G cg20560298 chr2:73613845 ALMS1 0.36 5.82 0.3 1.36e-8 Schizophrenia; LIHC cis rs57221529 0.709 rs72706612 chr5:561198 C/T cg09021430 chr5:549028 NA -0.45 -9.09 -0.44 8.22e-18 Lung disease severity in cystic fibrosis; LIHC cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg20607798 chr8:58055168 NA 0.49 6.22 0.32 1.48e-9 Developmental language disorder (linguistic errors); LIHC cis rs4237845 0.837 rs7963992 chr12:58295949 G/C cg04478727 chr12:58166393 METTL1;FAM119B 0.42 5.89 0.3 9.48e-9 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.933 rs3114848 chr16:89452771 G/A cg01788221 chr16:89496183 ANKRD11 -0.39 -6.12 -0.31 2.63e-9 Multiple myeloma (IgH translocation); LIHC cis rs5770917 1.000 rs17848459 chr22:51012311 G/T cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.4 -5.86 -0.3 1.08e-8 Narcolepsy; LIHC cis rs11951515 0.508 rs7705166 chr5:43587448 G/T cg01983248 chr5:43482804 C5orf28 -0.37 -6.08 -0.31 3.26e-9 Metabolite levels (X-11787); LIHC cis rs2153535 0.580 rs9379210 chr6:8461928 C/G cg23788917 chr6:8435910 SLC35B3 0.61 8.65 0.42 1.99e-16 Motion sickness; LIHC trans rs1349882 1.000 rs1349882 chr2:52949318 G/T cg13127694 chr14:104656055 NA 0.32 6.07 0.31 3.33e-9 Asymmetrical dimethylarginine levels; LIHC trans rs6489882 0.703 rs10774674 chr12:113361174 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.95e-10 Chronic lymphocytic leukemia; LIHC cis rs12808519 0.688 rs3740640 chr11:69587583 C/T cg19831575 chr11:69590090 FGF4 -0.52 -7.4 -0.37 1.08e-12 Urate levels in overweight individuals; LIHC cis rs7818688 0.697 rs10504939 chr8:95983354 C/G cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg18803079 chr1:64014643 EFCAB7;DLEU2L 0.44 6.09 0.31 3.07e-9 Myopia (pathological); LIHC cis rs8014204 0.816 rs11159107 chr14:75341266 C/A cg08847533 chr14:75593920 NEK9 -0.35 -6.0 -0.31 5.02e-9 Caffeine consumption; LIHC cis rs67478160 0.643 rs4900600 chr14:104291839 A/G cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.19 -0.36 4.24e-12 Schizophrenia; LIHC cis rs9733 0.596 rs1336898 chr1:150665050 G/A cg18016565 chr1:150552671 MCL1 0.59 11.56 0.53 2.57e-26 Tonsillectomy; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13232119 chr14:69283484 NA -0.48 -6.78 -0.34 5.23e-11 Systolic blood pressure; LIHC cis rs490234 0.841 rs13291593 chr9:128228483 A/G cg14078157 chr9:128172775 NA -0.39 -6.63 -0.34 1.28e-10 Mean arterial pressure; LIHC cis rs3736594 0.546 rs7571558 chr2:27839832 C/G cg27432699 chr2:27873401 GPN1 0.46 6.8 0.34 4.79e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg27432699 chr2:27873401 GPN1 -0.54 -7.82 -0.39 6.44e-14 Total body bone mineral density; LIHC cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg02931644 chr1:25747376 RHCE 0.35 7.6 0.38 2.82e-13 Erythrocyte sedimentation rate; LIHC cis rs2274273 0.773 rs10147765 chr14:55827826 G/A cg01864836 chr14:55583639 NA -0.38 -6.76 -0.34 6.02e-11 Protein biomarker; LIHC cis rs17152411 0.895 rs7080330 chr10:126585673 A/G cg07906193 chr10:126599966 NA 0.44 6.96 0.35 1.78e-11 Height; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg27432699 chr2:27873401 GPN1 -0.52 -7.47 -0.37 6.89e-13 Total body bone mineral density; LIHC cis rs2204008 0.687 rs2320523 chr12:38251397 T/C cg13010199 chr12:38710504 ALG10B 0.48 5.8 0.3 1.47e-8 Bladder cancer; LIHC cis rs7937682 0.883 rs549143 chr11:111463779 C/T cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg04267008 chr7:1944627 MAD1L1 -0.56 -8.95 -0.44 2.29e-17 Bipolar disorder and schizophrenia; LIHC cis rs11971779 0.648 rs66463279 chr7:139118661 A/G cg07862535 chr7:139043722 LUC7L2 0.63 10.91 0.51 5.59e-24 Diisocyanate-induced asthma; LIHC cis rs6456156 0.583 rs7748224 chr6:167456860 C/T cg12798992 chr6:167411361 FGFR1OP 0.43 6.65 0.34 1.18e-10 Primary biliary cholangitis; LIHC trans rs2727020 0.930 rs1164686 chr11:49291822 C/T cg03929089 chr4:120376271 NA 0.68 10.17 0.48 2.06e-21 Coronary artery disease; LIHC cis rs28453840 1 rs28453840 chr2:136522941 G/A cg25344623 chr2:136566232 LCT 0.45 9.02 0.44 1.42e-17 Cholesterol, total; LIHC cis rs6429082 0.518 rs1812350 chr1:235659920 C/A cg26050004 chr1:235667680 B3GALNT2 0.83 15.0 0.63 1.88e-39 Adiposity; LIHC cis rs8078723 1.000 rs2227336 chr17:38174855 T/G cg17467752 chr17:38218738 THRA 0.75 13.68 0.59 2.85e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs1814175 0.647 rs1404157 chr11:49917301 G/C cg15704280 chr7:45808275 SEPT13 -0.69 -11.9 -0.54 1.47e-27 Height; LIHC cis rs61990749 0.597 rs59848135 chr14:78129000 G/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.53 -8.71 -0.43 1.31e-16 Fibroblast growth factor basic levels; LIHC cis rs763121 0.853 rs1065201 chr22:39069510 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs6429082 0.713 rs867363 chr1:235579727 A/G cg26050004 chr1:235667680 B3GALNT2 -0.48 -7.26 -0.37 2.59e-12 Adiposity; LIHC cis rs903552 0.866 rs11247296 chr15:102007919 T/C cg25677261 chr15:102009856 PCSK6 -0.49 -6.8 -0.35 4.59e-11 Diabetic kidney disease; LIHC trans rs11722228 0.522 rs77691548 chr4:10136115 T/G cg26043149 chr18:55253948 FECH 0.99 14.35 0.61 6.94e-37 Gout;Urate levels;Serum uric acid levels; LIHC cis rs2731664 0.792 rs385981 chr5:176886539 C/T cg23176889 chr5:176863531 GRK6 -0.72 -12.76 -0.57 9.29e-31 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs1051424 0.651 rs1292063 chr17:57907768 T/A cg02344993 chr17:57696989 CLTC -0.72 -12.35 -0.56 3.14e-29 Obesity-related traits; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg26949087 chr2:26467503 HADHB;HADHA 0.44 6.09 0.31 3.09e-9 Migraine with aura; LIHC cis rs6732160 0.574 rs12465780 chr2:73472012 A/G cg24220031 chr2:73402428 NA 0.27 5.82 0.3 1.38e-8 Intelligence (multi-trait analysis); LIHC cis rs10508774 1.000 rs12241523 chr10:32976098 C/T cg01819863 chr10:32635814 EPC1 0.63 5.88 0.3 9.88e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs66887589 0.967 rs1155577 chr4:120449810 C/T cg25214090 chr10:38739885 LOC399744 -0.38 -6.22 -0.32 1.48e-9 Diastolic blood pressure; LIHC cis rs911119 0.955 rs1011226 chr20:23605833 G/T cg16589663 chr20:23618590 CST3 -0.74 -8.01 -0.4 1.76e-14 Chronic kidney disease; LIHC trans rs66887589 0.592 rs2175383 chr4:120215836 C/A cg25214090 chr10:38739885 LOC399744 0.44 6.94 0.35 2e-11 Diastolic blood pressure; LIHC cis rs7412746 0.611 rs4970985 chr1:150887442 C/T cg15448220 chr1:150897856 SETDB1 -0.36 -5.77 -0.3 1.81e-8 Melanoma; LIHC cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.89 -10.72 -0.5 2.55e-23 Platelet count; LIHC trans rs7618501 0.633 rs11130234 chr3:50024758 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.48 0.46 4.54e-19 Intelligence (multi-trait analysis); LIHC cis rs4930103 0.782 rs10840167 chr11:2022023 G/T cg06197492 chr11:2016605 H19 0.39 6.4 0.33 5.2400000000000005e-10 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs3096299 0.933 rs2965824 chr16:89455306 A/G cg08822215 chr16:89438651 ANKRD11 -0.43 -6.81 -0.35 4.35e-11 Multiple myeloma (IgH translocation); LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.22 0.55 9.92e-29 Prudent dietary pattern; LIHC cis rs9811920 0.609 rs793467 chr3:99539664 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.42 5.84 0.3 1.22e-8 Axial length; LIHC cis rs2439831 0.681 rs526450 chr15:43599325 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.85 15.77 0.65 1.71e-42 Lung cancer in ever smokers; LIHC cis rs80282103 0.764 rs12244052 chr10:1103266 G/A cg18964960 chr10:1102726 WDR37 0.67 6.21 0.32 1.53e-9 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs4960411 chr6:8438231 C/G cg07606381 chr6:8435919 SLC35B3 0.79 11.67 0.53 1.03e-26 Motion sickness; LIHC cis rs7903847 0.619 rs9888116 chr10:99159482 G/A cg20016023 chr10:99160130 RRP12 -0.43 -6.81 -0.35 4.27e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs9420 0.961 rs77993055 chr11:57522840 C/T cg19752551 chr11:57585705 CTNND1 -0.52 -7.34 -0.37 1.56e-12 Schizophrenia; LIHC cis rs2016586 0.796 rs5750158 chr22:36101567 T/C cg26342177 chr22:36113512 APOL5 -0.39 -6.74 -0.34 6.73e-11 Body mass index; LIHC cis rs3784262 1.000 rs4646622 chr15:58257199 A/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.38 -0.33 5.77e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg10360323 chr17:41437877 NA 0.4 5.92 0.31 7.69e-9 Menopause (age at onset); LIHC trans rs9858542 1.000 rs34762726 chr3:49689210 G/A cg21659725 chr3:3221576 CRBN -0.57 -6.34 -0.32 7.34e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs904251 0.504 rs9380677 chr6:37480366 A/G cg01843034 chr6:37503916 NA -0.47 -7.99 -0.4 2.12e-14 Cognitive performance; LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg19635926 chr16:89946313 TCF25 0.5 7.02 0.35 1.18e-11 Skin colour saturation; LIHC cis rs2153535 0.580 rs4451187 chr6:8473910 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.03 0.4 1.59e-14 Motion sickness; LIHC cis rs9790314 0.502 rs34972965 chr3:160984296 G/A cg17135325 chr3:160939158 NMD3 0.55 7.84 0.39 5.59e-14 Morning vs. evening chronotype; LIHC cis rs7666738 0.830 rs6843777 chr4:98866635 T/A cg05340658 chr4:99064831 C4orf37 0.67 12.03 0.55 4.99e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs7659604 0.518 rs17452156 chr4:122733623 T/C cg19748678 chr4:122722346 EXOSC9 0.67 11.07 0.51 1.47e-24 Type 2 diabetes; LIHC cis rs6933660 0.683 rs8180642 chr6:151756612 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.59 9.63 0.46 1.44e-19 Menarche (age at onset); LIHC cis rs9457247 0.602 rs17615336 chr6:167506734 A/G cg23791538 chr6:167370224 RNASET2 -0.5 -7.5 -0.38 5.63e-13 Crohn's disease; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg26338869 chr17:61819248 STRADA 0.61 8.91 0.43 3.14e-17 Prudent dietary pattern; LIHC cis rs939574 1.000 rs2071385 chr2:220118782 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.97 10.48 0.49 1.75e-22 Platelet distribution width; LIHC cis rs919433 0.963 rs13033821 chr2:198173536 T/G cg03934865 chr2:198174659 NA -0.57 -9.1 -0.44 7.61e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4891159 0.790 rs7241485 chr18:74122325 C/T cg24786174 chr18:74118243 ZNF516 -0.78 -14.35 -0.61 6.94e-37 Longevity; LIHC cis rs6831352 0.918 rs2602893 chr4:100044095 G/T cg12011299 chr4:100065546 ADH4 0.62 10.4 0.49 3.54e-22 Alcohol dependence; LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs892961 0.932 rs2170863 chr17:75415037 C/T cg01320579 chr17:75405842 SEPT9 0.52 7.33 0.37 1.64e-12 Airflow obstruction; LIHC cis rs9733 0.596 rs6661872 chr1:150628357 C/G cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs1691799 0.899 rs2951656 chr12:66732273 T/G cg16791601 chr12:66731901 HELB -0.54 -12.96 -0.57 1.61e-31 White blood cell count (basophil); LIHC cis rs9326248 0.861 rs7931335 chr11:117036805 C/T cg11861562 chr11:117069780 TAGLN 0.36 5.77 0.3 1.82e-8 Blood protein levels; LIHC cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.42 0.45 6.79e-19 Platelet count; LIHC cis rs10508774 0.810 rs12245661 chr10:32735017 A/T cg01819863 chr10:32635814 EPC1 0.61 5.88 0.3 9.61e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs875971 0.545 rs67397473 chr7:65633305 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.49 0.38 5.77e-13 Aortic root size; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.97 -0.35 1.6e-11 Diastolic blood pressure; LIHC cis rs6570726 0.902 rs396681 chr6:145853603 T/C cg23711669 chr6:146136114 FBXO30 0.56 9.99 0.48 8.54e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs2599510 0.729 rs1135484 chr2:32749060 G/A cg02381751 chr2:32503542 YIPF4 0.49 6.45 0.33 3.81e-10 Interleukin-18 levels; LIHC cis rs12744310 1.000 rs12035353 chr1:41769337 G/A cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg14298269 chr14:102689372 WDR20 0.52 6.94 0.35 1.96e-11 Hip circumference; LIHC cis rs2576037 0.899 rs2576035 chr18:44587654 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.48 -7.24 -0.36 2.93e-12 Personality dimensions; LIHC cis rs8067354 0.645 rs7215180 chr17:57822354 A/G cg13753209 chr17:57696993 CLTC 0.73 11.52 0.53 3.71e-26 Hemoglobin concentration; LIHC cis rs600806 0.850 rs4970751 chr1:109896600 A/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs6088580 0.634 rs13041646 chr20:33082881 T/A cg08999081 chr20:33150536 PIGU 0.68 13.52 0.59 1.12e-33 Glomerular filtration rate (creatinine); LIHC cis rs6964587 1.000 rs61244255 chr7:91751662 C/T cg17063962 chr7:91808500 NA 1.0 18.64 0.71 5.38e-54 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17150246 chr1:161068070 KLHDC9 0.44 6.36 0.33 6.34e-10 Pancreatic cancer; LIHC cis rs5769765 0.728 rs6520064 chr22:50294469 A/G cg02269571 chr22:50332266 NA -0.61 -8.7 -0.43 1.44e-16 Schizophrenia; LIHC cis rs911119 0.954 rs2424582 chr20:23622550 A/G cg16589663 chr20:23618590 CST3 0.77 8.22 0.41 4.21e-15 Chronic kidney disease; LIHC cis rs35160687 0.623 rs1863060 chr2:86511456 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 0.37 5.9 0.3 8.57e-9 Night sleep phenotypes; LIHC cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg11644478 chr21:40555479 PSMG1 0.44 6.83 0.35 4e-11 Cognitive function; LIHC cis rs116095464 0.558 rs13357299 chr5:242211 T/C cg22857025 chr5:266934 NA -1.48 -18.17 -0.7 4.09e-52 Breast cancer; LIHC cis rs17685 0.712 rs1639620 chr7:75704090 A/G cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20982606 chr12:109535391 UNG 0.62 8.16 0.4 6.46e-15 Lung function (FEV1/FVC); LIHC cis rs12765878 1.000 rs4918067 chr10:105644636 A/C cg11005552 chr10:105648138 OBFC1 0.39 6.03 0.31 4.35e-9 Coronary artery disease; LIHC cis rs9916302 0.904 rs4795355 chr17:37427382 C/T cg00129232 chr17:37814104 STARD3 -0.4 -6.45 -0.33 3.88e-10 Glomerular filtration rate (creatinine); LIHC cis rs7937682 0.889 rs490199 chr11:111487890 A/G cg22437258 chr11:111473054 SIK2 0.51 5.79 0.3 1.63e-8 Primary sclerosing cholangitis; LIHC cis rs7408868 0.831 rs7245850 chr19:15274585 A/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs7903847 0.642 rs10786339 chr10:99153076 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1865760 0.566 rs1539183 chr6:26075051 G/C cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs611744 0.810 rs619227 chr8:109215100 C/A cg18478394 chr8:109455254 TTC35 0.38 6.35 0.32 6.88e-10 Dupuytren's disease; LIHC cis rs9522267 0.708 rs914032 chr13:112241019 G/A cg10483660 chr13:112241077 NA 0.23 5.93 0.31 7.28e-9 Hepatitis; LIHC cis rs6089584 0.853 rs1740367 chr20:60574834 C/T cg12751644 chr20:60527061 NA -0.36 -5.87 -0.3 1.01e-8 Body mass index; LIHC cis rs7582720 0.945 rs114604411 chr2:203811912 A/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs262150 0.501 rs2730206 chr7:158815173 G/C cg19418458 chr7:158789849 NA -0.41 -6.83 -0.35 3.82e-11 Facial morphology (factor 20); LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg00106254 chr7:1943704 MAD1L1 -0.47 -7.78 -0.39 8.43e-14 Bipolar disorder and schizophrenia; LIHC cis rs3749237 0.595 rs6784820 chr3:49450864 C/T cg07636037 chr3:49044803 WDR6 -0.5 -7.46 -0.37 7.41e-13 Resting heart rate; LIHC cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.765 rs7591794 chr2:99567514 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -8.45 -0.42 8.28e-16 Chronic sinus infection; LIHC cis rs751728 1.000 rs2395449 chr6:33728755 T/A cg25922239 chr6:33757077 LEMD2 0.47 7.67 0.38 1.77e-13 Crohn's disease; LIHC cis rs1577917 1.000 rs12216328 chr6:86703418 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.75 -0.47 5.79e-20 Response to antipsychotic treatment; LIHC cis rs736408 0.812 rs2270197 chr3:52824095 T/G cg18404041 chr3:52824283 ITIH1 -0.67 -10.96 -0.51 3.68e-24 Bipolar disorder; LIHC cis rs8083850 0.667 rs28868998 chr18:50842731 T/C cg24270629 chr18:50823537 DCC -0.57 -8.56 -0.42 3.76e-16 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs6790466 chr3:134197740 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.7 -12.43 -0.56 1.53e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1862618 0.525 rs2662016 chr5:56269047 A/G cg24531977 chr5:56204891 C5orf35 0.66 8.97 0.44 1.93e-17 Initial pursuit acceleration; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg11070056 chr1:107600091 PRMT6 0.68 11.61 0.53 1.68e-26 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07472159 chr6:116447667 COL10A1;NT5DC1 0.29 6.05 0.31 3.84e-9 Cognitive function; LIHC cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg00343986 chr7:65444356 GUSB 0.44 6.26 0.32 1.18e-9 Calcium levels; LIHC cis rs3820068 0.705 rs72645803 chr1:15868232 G/A cg17385448 chr1:15911702 AGMAT 0.4 6.55 0.33 2.1e-10 Systolic blood pressure; LIHC cis rs9527 0.518 rs4633383 chr10:104795723 T/G cg15744005 chr10:104629667 AS3MT -0.47 -6.3 -0.32 9.41e-10 Arsenic metabolism; LIHC cis rs360798 0.512 rs1906198 chr2:62946658 C/T cg17519650 chr2:63277830 OTX1 0.48 7.24 0.36 3e-12 Coronary artery disease; LIHC cis rs7833986 0.501 rs2976018 chr8:57014752 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.06e-16 Height; LIHC cis rs35110281 0.627 rs11701746 chr21:44975137 C/T cg04455712 chr21:45112962 RRP1B 0.42 7.13 0.36 5.84e-12 Mean corpuscular volume; LIHC cis rs13217239 0.646 rs7768407 chr6:27016795 G/A cg12292205 chr6:26970375 C6orf41 0.45 7.81 0.39 6.91e-14 Schizophrenia; LIHC cis rs1559088 1.000 rs12979164 chr19:33553228 G/C cg27124370 chr19:33622961 WDR88 0.47 7.09 0.36 7.54e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs921968 0.643 rs678218 chr2:219379709 C/A cg17980119 chr2:219472607 PLCD4 0.36 6.14 0.31 2.34e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs611744 0.647 rs585077 chr8:109245497 C/T cg21045802 chr8:109455806 TTC35 0.57 10.07 0.48 4.52e-21 Dupuytren's disease; LIHC cis rs6424115 1.000 rs7519554 chr1:24154566 T/A cg15997130 chr1:24165203 NA -0.47 -9.62 -0.46 1.55e-19 Immature fraction of reticulocytes; LIHC cis rs2455799 0.552 rs2470516 chr3:15759050 T/G cg12698662 chr3:15914712 MIR563 -0.41 -7.65 -0.38 2.02e-13 Mean platelet volume; LIHC cis rs2599510 0.744 rs2254106 chr2:32768797 G/A cg02381751 chr2:32503542 YIPF4 0.47 6.24 0.32 1.3e-9 Interleukin-18 levels; LIHC cis rs7715806 0.500 rs72633985 chr5:75006384 A/G cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs941873 0.835 rs10762859 chr10:81103370 T/A cg11057378 chr10:81107060 PPIF 0.35 5.79 0.3 1.59e-8 Height; LIHC cis rs743757 0.878 rs6786523 chr3:50524221 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.47 -7.15 -0.36 5.15e-12 Diastolic blood pressure; LIHC cis rs8067354 0.958 rs2333563 chr17:57839568 A/G cg02344993 chr17:57696989 CLTC 0.54 8.55 0.42 4.26e-16 Hemoglobin concentration; LIHC cis rs3812111 0.676 rs9488857 chr6:116485722 C/T cg08036074 chr6:116424633 NT5DC1 -0.52 -8.69 -0.43 1.49e-16 Age-related macular degeneration; LIHC cis rs9596863 0.898 rs35359752 chr13:54364643 T/C ch.13.53330881F chr13:54432880 NA 0.43 5.8 0.3 1.54e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2650000 0.798 rs2701175 chr12:121391671 C/A cg02403541 chr12:121454288 C12orf43 -0.43 -7.47 -0.37 6.77e-13 Metabolic traits;LDL cholesterol; LIHC cis rs9393692 0.645 rs6939048 chr6:26327953 G/A cg00631329 chr6:26305371 NA -0.51 -7.93 -0.39 3.14e-14 Educational attainment; LIHC cis rs4906332 0.782 rs12880224 chr14:104006414 C/G cg19000871 chr14:103996768 TRMT61A -0.58 -9.26 -0.45 2.28e-18 Coronary artery disease; LIHC cis rs7107174 0.786 rs4945266 chr11:78027488 A/G cg02023728 chr11:77925099 USP35 0.52 9.83 0.47 2.9e-20 Testicular germ cell tumor; LIHC cis rs79839061 0.610 rs12651368 chr4:856787 G/A cg07828340 chr4:882639 GAK 0.83 7.02 0.36 1.18e-11 Intelligence (multi-trait analysis); LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.85 -0.3 1.16e-8 Total body bone mineral density; LIHC cis rs875971 0.545 rs1909508 chr7:65766353 G/T cg11764359 chr7:65958608 NA 0.57 8.11 0.4 8.96e-15 Aortic root size; LIHC cis rs9640161 0.830 rs6722 chr7:150068933 T/C cg17279839 chr7:150038598 RARRES2 0.4 7.97 0.4 2.47e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7224737 1.000 rs7224737 chr17:40289364 A/G cg20291162 chr17:40259547 DHX58 0.39 6.43 0.33 4.29e-10 Fibrinogen levels; LIHC cis rs9902453 0.808 rs62068617 chr17:28144728 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.78 0.54 4.01e-27 Coffee consumption (cups per day); LIHC cis rs3857067 1.000 rs6532462 chr4:95026833 G/T cg11021082 chr4:95130006 SMARCAD1 -0.41 -7.35 -0.37 1.43e-12 QT interval; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06719391 chr11:2554330 KCNQ1 0.4 6.05 0.31 3.78e-9 Cognitive function; LIHC cis rs1419980 0.673 rs2377086 chr12:7753798 C/T cg10578777 chr12:7781093 NA 0.49 8.68 0.43 1.59e-16 HDL cholesterol levels; LIHC cis rs7534824 0.625 rs61782084 chr1:101515298 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.72 7.33 0.37 1.72e-12 Refractive astigmatism; LIHC cis rs1419980 0.730 rs11054868 chr12:7770601 A/T cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg24250549 chr1:154909240 PMVK 0.67 10.56 0.5 9.86e-23 Prostate cancer; LIHC cis rs7953249 0.514 rs1169312 chr12:121441461 G/T cg25281562 chr12:121454272 C12orf43 0.33 5.78 0.3 1.68e-8 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs3820068 0.603 rs6429753 chr1:15900537 A/G cg17385448 chr1:15911702 AGMAT 0.37 6.1 0.31 2.87e-9 Systolic blood pressure; LIHC cis rs17253792 0.915 rs78089630 chr14:56178584 G/C cg01858014 chr14:56050164 KTN1 -0.76 -8.08 -0.4 1.1e-14 Putamen volume; LIHC cis rs6542838 0.580 rs1607256 chr2:99543444 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.47 -0.33 3.37e-10 Fear of minor pain; LIHC cis rs79149102 0.579 rs78664321 chr15:75339575 G/A cg17294928 chr15:75287854 SCAMP5 -0.54 -6.6 -0.34 1.56e-10 Lung cancer; LIHC cis rs986417 0.892 rs11628559 chr14:61038153 G/C cg27398547 chr14:60952738 C14orf39 0.7 7.66 0.38 1.88e-13 Gut microbiota (bacterial taxa); LIHC cis rs17106184 1.000 rs59622625 chr1:50973264 C/T cg07174182 chr1:51127561 FAF1 -0.58 -6.31 -0.32 8.71e-10 Type 2 diabetes; LIHC cis rs769267 0.965 rs2315025 chr19:19426609 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.6 9.69 0.46 9.15e-20 Tonsillectomy; LIHC cis rs10197940 0.578 rs2432957 chr2:152287897 A/C cg06191203 chr2:152266755 RIF1 -0.43 -7.45 -0.37 7.62e-13 Lung cancer; LIHC cis rs2235642 0.821 rs8051895 chr16:1602811 A/G cg03034668 chr16:1723424 CRAMP1L -0.41 -7.29 -0.37 2.18e-12 Coronary artery disease; LIHC cis rs12478296 1.000 rs56323081 chr2:243040807 A/G cg18898632 chr2:242989856 NA -0.69 -8.66 -0.42 1.91e-16 Obesity-related traits; LIHC cis rs921968 0.643 rs585859 chr2:219383121 C/T cg18887096 chr2:219472410 PLCD4 0.4 6.97 0.35 1.67e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.817 rs10769641 chr11:49960141 A/G cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs1707322 0.721 rs10890344 chr1:46166090 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9902453 0.730 rs3794808 chr17:28531793 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.53 7.82 0.39 6.41e-14 Coffee consumption (cups per day); LIHC cis rs11971779 0.680 rs7808740 chr7:139028955 G/T cg07862535 chr7:139043722 LUC7L2 0.6 10.21 0.48 1.48e-21 Diisocyanate-induced asthma; LIHC cis rs7771547 0.573 rs517890 chr6:36397786 G/C cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Platelet distribution width; LIHC cis rs950169 0.580 rs62021208 chr15:85196244 G/A cg17507749 chr15:85114479 UBE2QP1 0.69 7.97 0.4 2.46e-14 Schizophrenia; LIHC cis rs116095464 0.558 rs55776650 chr5:273826 G/A cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs7106204 0.514 rs12789549 chr11:24254726 C/G ch.11.24196551F chr11:24239977 NA 0.81 11.54 0.53 3.14e-26 Response to Homoharringtonine (cytotoxicity); LIHC cis rs1005277 0.602 rs1831315 chr10:38473353 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.24 -0.32 1.28e-9 Extrinsic epigenetic age acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25372841 chr8:145675454 CYHR1 0.42 6.49 0.33 3.05e-10 Longevity; LIHC cis rs3093024 0.595 rs4458654 chr6:167476068 A/C cg07741184 chr6:167504864 NA 0.35 8.08 0.4 1.15e-14 Rheumatoid arthritis; LIHC cis rs11229555 0.609 rs7128459 chr11:58179291 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg11644478 chr21:40555479 PSMG1 0.44 6.87 0.35 3.06e-11 Cognitive function; LIHC cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg01788221 chr16:89496183 ANKRD11 -0.39 -6.04 -0.31 4.12e-9 Multiple myeloma (IgH translocation); LIHC cis rs10751667 0.666 rs7395488 chr11:954111 T/C cg06064525 chr11:970664 AP2A2 -0.56 -15.03 -0.63 1.52e-39 Alzheimer's disease (late onset); LIHC cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg03396347 chr1:1875803 NA -0.45 -8.27 -0.41 2.98e-15 Body mass index; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg24667363 chr3:158362181 GFM1 -0.39 -6.22 -0.32 1.49e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs60843830 0.964 rs62114538 chr2:256116 G/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.62 9.16 0.44 4.94e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg12016809 chr21:47604291 C21orf56 0.49 7.61 0.38 2.67e-13 Testicular germ cell tumor; LIHC cis rs9326248 0.953 rs488962 chr11:117072525 C/T cg15534755 chr11:117069859 TAGLN -0.39 -6.56 -0.33 1.96e-10 Blood protein levels; LIHC cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.59 0.38 3.09e-13 Electroencephalogram traits; LIHC cis rs7940866 0.803 rs10894307 chr11:130876350 G/A cg12179176 chr11:130786555 SNX19 0.57 8.27 0.41 3.01e-15 Schizophrenia; LIHC cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg02290350 chr8:58132656 NA 0.5 9.72 0.47 7.22e-20 Developmental language disorder (linguistic errors); LIHC cis rs3736594 0.918 rs12471347 chr2:27981655 G/C cg27432699 chr2:27873401 GPN1 0.4 6.17 0.32 1.92e-9 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC trans rs11098499 0.954 rs10024844 chr4:120311528 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs8017423 0.647 rs12589952 chr14:90821364 T/C cg04374321 chr14:90722782 PSMC1 -0.49 -7.25 -0.36 2.81e-12 Mortality in heart failure; LIHC cis rs4268898 1.000 rs10195436 chr2:24436112 C/T cg06627628 chr2:24431161 ITSN2 0.51 7.31 0.37 1.93e-12 Asthma; LIHC cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg17971929 chr21:40555470 PSMG1 -0.45 -6.9 -0.35 2.52e-11 Cognitive function; LIHC cis rs1816752 0.666 rs7994022 chr13:25017230 A/G cg22771759 chr13:24902376 NA 0.31 6.48 0.33 3.25e-10 Obesity-related traits; LIHC cis rs7131987 0.650 rs7311912 chr12:29475703 G/C cg00204748 chr12:29376779 FAR2 0.4 7.49 0.38 5.92e-13 QT interval; LIHC cis rs1008375 0.932 rs6845288 chr4:17665498 A/T cg16339924 chr4:17578868 LAP3 -0.48 -6.31 -0.32 8.49e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs71007656 1 rs71007656 chr10:37970845 CGGCTG/C cg00409905 chr10:38381863 ZNF37A -0.56 -9.58 -0.46 2.1e-19 Extrinsic epigenetic age acceleration; LIHC cis rs68170813 0.559 rs80212020 chr7:106957596 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.12e-9 Coronary artery disease; LIHC cis rs3096299 0.967 rs2965935 chr16:89481274 C/T cg06640241 chr16:89574553 SPG7 -0.64 -10.3 -0.49 7.28e-22 Multiple myeloma (IgH translocation); LIHC cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC trans rs6732426 1.000 rs6732426 chr2:43587504 C/T cg10773526 chr4:143327279 INPP4B 0.35 6.07 0.31 3.46e-9 Hair morphology; LIHC cis rs72781680 1.000 rs72796326 chr2:24137047 G/A cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC trans rs9914544 1.000 rs7223231 chr17:18811846 C/T cg04702396 chr17:15466718 FAM18B2 0.45 6.97 0.35 1.65e-11 Educational attainment (years of education); LIHC cis rs2303745 0.589 rs8103523 chr19:17398269 A/G cg10664184 chr19:17420304 DDA1 0.46 5.81 0.3 1.41e-8 Systemic lupus erythematosus; LIHC cis rs6684514 1.000 rs12141236 chr1:156302575 A/C cg16558208 chr1:156270281 VHLL 0.54 10.31 0.49 7.15e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs701145 0.617 rs355775 chr3:154036129 A/G cg16511985 chr3:153974050 SGEF 0.4 8.52 0.42 5.02e-16 Coronary artery disease; LIHC cis rs4268898 0.662 rs59996104 chr2:24404064 C/T cg06627628 chr2:24431161 ITSN2 -0.69 -8.98 -0.44 1.9e-17 Asthma; LIHC cis rs919433 0.963 rs10199410 chr2:198155776 A/T cg03934865 chr2:198174659 NA -0.61 -9.93 -0.47 1.34e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs916888 0.821 rs70600 chr17:44860021 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.84 0.35 3.7e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs651907 0.557 rs11914318 chr3:101453858 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.4 0.52 9.54e-26 Colorectal cancer; LIHC trans rs1814175 0.645 rs28538913 chr11:50040718 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs11190604 1.000 rs2495755 chr10:102324649 A/C cg07080220 chr10:102295463 HIF1AN 0.53 7.18 0.36 4.49e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs208515 0.525 rs12215007 chr6:66671008 C/T cg07460842 chr6:66804631 NA -0.77 -9.18 -0.44 4.35e-18 Exhaled nitric oxide levels; LIHC cis rs10256972 0.869 rs1007766 chr7:1034903 G/A cg07308232 chr7:1071921 C7orf50 -0.49 -7.86 -0.39 5.08e-14 Longevity;Endometriosis; LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg05834845 chr3:195489306 MUC4 0.63 9.7 0.46 8.33e-20 Lung disease severity in cystic fibrosis; LIHC cis rs2463822 0.920 rs11828383 chr11:62067818 C/T cg06239285 chr11:62104954 ASRGL1 -0.95 -6.46 -0.33 3.63e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs12479064 0.671 rs62155807 chr2:100076579 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.62 -7.72 -0.39 1.31e-13 Chronic sinus infection; LIHC cis rs10849893 0.538 rs4980986 chr12:121914808 A/T cg01154721 chr12:121881891 KDM2B -0.53 -8.9 -0.43 3.31e-17 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs963731 0.649 rs2123876 chr2:39255873 C/G cg04010122 chr2:39346883 SOS1 -0.72 -6.07 -0.31 3.39e-9 Corticobasal degeneration; LIHC cis rs7512552 0.839 rs1260421 chr1:150357780 G/A cg15654264 chr1:150340011 RPRD2 0.69 11.4 0.52 9.57e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs11190604 1.000 rs7080356 chr10:102266735 A/C cg07080220 chr10:102295463 HIF1AN 0.55 8.0 0.4 2.01e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg11764359 chr7:65958608 NA 0.56 5.99 0.31 5.28e-9 Diabetic kidney disease; LIHC cis rs9902453 1.000 rs7222308 chr17:28277041 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 12.2 0.55 1.13e-28 Coffee consumption (cups per day); LIHC cis rs6502050 0.835 rs4789677 chr17:80119842 A/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg10590442 chr11:124633181 ESAM 0.44 6.55 0.33 2.11e-10 Triglycerides; LIHC cis rs9733 0.596 rs72702523 chr1:150650425 G/T cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Tonsillectomy; LIHC cis rs79387448 0.745 rs2310294 chr2:103165706 A/G cg09003973 chr2:102972529 NA 0.88 7.64 0.38 2.25e-13 Gut microbiota (bacterial taxa); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05619320 chr4:123653606 BBS12;LOC729338 0.32 6.17 0.32 1.94e-9 Calcium levels; LIHC cis rs7131987 0.903 rs10843373 chr12:29420608 A/T cg05697976 chr12:29376483 FAR2 0.32 6.65 0.34 1.13e-10 QT interval; LIHC cis rs6665290 0.904 rs2297415 chr1:227172903 G/A cg10327440 chr1:227177885 CDC42BPA -1.18 -26.56 -0.82 4.03e-85 Myeloid white cell count; LIHC cis rs40363 0.645 rs250633 chr16:3523002 C/T cg22508957 chr16:3507546 NAT15 0.46 8.92 0.43 2.86e-17 Tuberculosis; LIHC cis rs1580019 0.885 rs3801331 chr7:32497039 A/G cg07520158 chr7:32535189 LSM5;AVL9 -0.45 -6.03 -0.31 4.23e-9 Cognitive ability; LIHC cis rs7786877 0.587 rs56328569 chr7:100202219 C/G cg00334542 chr7:100209784 MOSPD3 -0.63 -5.89 -0.3 9.43e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg25387593 chr11:118927868 HYOU1 -0.48 -6.36 -0.33 6.62e-10 Lung cancer in ever smokers; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22463517 chr17:26988906 SDF2;SUPT6H 0.44 6.58 0.34 1.78e-10 Cognitive function; LIHC cis rs7072216 0.763 rs733345 chr10:100164215 G/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.46 -0.33 3.51e-10 Metabolite levels; LIHC cis rs2933343 0.621 rs728838 chr3:128589013 A/G cg24203234 chr3:128598194 ACAD9 0.43 6.06 0.31 3.59e-9 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22524267 chr4:4543474 STX18 0.41 6.92 0.35 2.27e-11 Cognitive function; LIHC cis rs9790314 1.000 rs336579 chr3:161086610 G/A cg04691961 chr3:161091175 C3orf57 -0.47 -7.46 -0.37 7.16e-13 Morning vs. evening chronotype; LIHC trans rs75804782 0.521 rs66477197 chr2:239403832 C/T cg01134436 chr17:81009848 B3GNTL1 0.83 6.94 0.35 1.94e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs9733 0.596 rs34140753 chr1:150642583 T/C cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs7123876 0.717 rs58249351 chr11:72463462 G/A cg03713592 chr11:72463424 ARAP1 0.59 6.53 0.33 2.31e-10 Body mass index; LIHC cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg05368731 chr17:41323189 NBR1 0.72 12.45 0.56 1.38e-29 Menopause (age at onset); LIHC cis rs875971 0.862 rs28491091 chr7:65669064 G/T cg18252515 chr7:66147081 NA 0.43 6.16 0.32 2.08e-9 Aortic root size; LIHC cis rs67478160 0.644 rs7159810 chr14:104294117 T/G cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.41 -0.37 9.71e-13 Schizophrenia; LIHC trans rs61931739 0.500 rs11053210 chr12:34461771 A/G cg26384229 chr12:38710491 ALG10B -0.64 -7.56 -0.38 3.84e-13 Morning vs. evening chronotype; LIHC cis rs7945718 0.967 rs4757945 chr11:12808718 A/G cg25843174 chr11:12811716 TEAD1 -0.36 -8.28 -0.41 2.89e-15 Educational attainment (years of education); LIHC cis rs7107174 1.000 rs2511182 chr11:77982130 G/C cg02023728 chr11:77925099 USP35 0.49 9.39 0.45 8.68e-19 Testicular germ cell tumor; LIHC cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg18404041 chr3:52824283 ITIH1 -0.55 -9.21 -0.45 3.3e-18 Electroencephalogram traits; LIHC cis rs1707322 0.717 rs3014249 chr1:46079493 A/G cg03146154 chr1:46216737 IPP -0.55 -8.96 -0.44 2.07e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs76297747 1 rs76297747 chr18:44665657 A/G cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Response to paliperidone in schizophrenia (Multivariate); LIHC cis rs12188164 0.543 rs2434695 chr5:464177 C/G cg16584290 chr5:462447 EXOC3 0.36 5.93 0.31 7.35e-9 Cystic fibrosis severity; LIHC cis rs9393692 0.846 rs9366651 chr6:26336696 G/T cg00631329 chr6:26305371 NA -0.44 -7.55 -0.38 3.96e-13 Educational attainment; LIHC cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg06634786 chr22:41940651 POLR3H -0.78 -8.54 -0.42 4.57e-16 Vitiligo; LIHC cis rs2932538 0.922 rs2273369 chr1:113072477 A/G cg22162597 chr1:113214053 CAPZA1 0.69 10.64 0.5 5.03e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs6545883 0.894 rs778157 chr2:61554289 C/G cg14146966 chr2:61757674 XPO1 0.45 7.61 0.38 2.71e-13 Tuberculosis; LIHC cis rs1552244 0.882 rs3732966 chr3:10015740 C/T cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg23262073 chr20:60523788 NA 0.34 7.11 0.36 6.69e-12 Obesity-related traits; LIHC cis rs11077998 0.869 rs6502123 chr17:80532170 T/C cg10255544 chr17:80519551 FOXK2 0.48 8.53 0.42 4.96e-16 Reticulocyte fraction of red cells; LIHC cis rs769267 0.930 rs2288852 chr19:19605348 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.87 0.39 4.88e-14 Tonsillectomy; LIHC cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg13397359 chr6:42928475 GNMT 0.82 12.16 0.55 1.64e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2836950 0.502 rs2150411 chr21:40574552 G/T cg17971929 chr21:40555470 PSMG1 -0.4 -6.02 -0.31 4.52e-9 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14103574 chr5:162932455 MAT2B 0.49 7.33 0.37 1.67e-12 Pancreatic cancer; LIHC cis rs611744 0.934 rs2848619 chr8:109198185 T/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs4728302 0.869 rs12707131 chr7:133620982 A/G cg10665199 chr7:133106180 EXOC4 0.36 6.25 0.32 1.21e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs1805008 0.535 rs4785621 chr16:90130735 C/T cg08547343 chr16:90038815 CENPBD1;AFG3L1 -0.74 -6.79 -0.34 4.93e-11 Skin colour saturation; LIHC cis rs2637266 0.597 rs846622 chr10:78543005 G/A cg18941641 chr10:78392320 NA 0.29 6.29 0.32 9.75e-10 Pulmonary function; LIHC cis rs4148883 0.689 rs1800760 chr4:100065626 A/T cg12011299 chr4:100065546 ADH4 0.35 6.85 0.35 3.49e-11 Alcohol dependence; LIHC cis rs17102423 0.594 rs4902360 chr14:65546722 A/C cg16583315 chr14:65563665 MAX -0.39 -7.94 -0.39 2.94e-14 Obesity-related traits; LIHC cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg05564831 chr3:52568323 NT5DC2 0.35 5.84 0.3 1.22e-8 Bipolar disorder; LIHC cis rs10878977 0.565 rs11177658 chr12:69810388 C/G cg17330252 chr12:69809627 NA 0.38 5.88 0.3 9.93e-9 Colorectal cancer; LIHC cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg06634786 chr22:41940651 POLR3H 0.75 7.6 0.38 2.91e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs13161895 1.000 rs35592104 chr5:179447661 A/T cg02702477 chr5:179499311 RNF130 0.76 10.52 0.49 1.27e-22 LDL cholesterol; LIHC cis rs6815814 0.851 rs17582893 chr4:38886420 G/A cg06935464 chr4:38784597 TLR10 0.43 6.42 0.33 4.45e-10 Breast cancer; LIHC cis rs17401966 0.894 rs12722830 chr1:10395134 A/G cg15208524 chr1:10270712 KIF1B 0.42 6.22 0.32 1.43e-9 Hepatocellular carcinoma; LIHC cis rs2274273 0.870 rs3825616 chr14:55853288 G/C cg01864836 chr14:55583639 NA -0.41 -7.55 -0.38 4.07e-13 Protein biomarker; LIHC cis rs10832963 1.000 rs4757676 chr11:18640477 C/T cg20219074 chr11:18656078 SPTY2D1 0.84 13.96 0.6 2.37e-35 Breast cancer; LIHC cis rs227584 0.663 rs3180912 chr17:42259463 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.41 7.49 0.38 6.12e-13 Bone mineral density (hip);Bone mineral density; LIHC cis rs10489202 0.634 rs11582396 chr1:168077636 C/T cg24449463 chr1:168025552 DCAF6 -0.44 -6.19 -0.32 1.68e-9 Schizophrenia; LIHC cis rs600806 0.813 rs4970759 chr1:109982213 C/A cg23091122 chr1:110024289 SYPL2 -0.49 -6.46 -0.33 3.51e-10 Intelligence (multi-trait analysis); LIHC cis rs2408955 0.522 rs10875721 chr12:48413593 A/G cg21466736 chr12:48725269 NA 0.6 8.1 0.4 9.95e-15 Glycated hemoglobin levels; LIHC cis rs986417 1.000 rs8021347 chr14:60952773 G/C cg27398547 chr14:60952738 C14orf39 0.82 9.57 0.46 2.22e-19 Gut microbiota (bacterial taxa); LIHC cis rs7264396 1.000 rs224435 chr20:34154087 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.94 -0.35 2.02e-11 Total cholesterol levels; LIHC cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg27170947 chr2:26402098 FAM59B -0.67 -8.43 -0.41 9.53e-16 Gut microbiome composition (summer); LIHC trans rs1814175 0.817 rs10769617 chr11:49810421 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3e-11 Height; LIHC cis rs2840044 1.000 rs7212704 chr17:33898897 C/T cg20932281 chr17:33905541 PEX12 0.42 5.76 0.3 1.9e-8 Response to radiotherapy in cancer (late toxicity); LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg11494091 chr17:61959527 GH2 0.44 8.04 0.4 1.48e-14 Prudent dietary pattern; LIHC cis rs644799 1.000 rs1944074 chr11:95511445 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.32 0.68 1.09e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9868809 0.881 rs57334642 chr3:48666795 C/T cg07636037 chr3:49044803 WDR6 -0.55 -6.39 -0.33 5.38e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs1881396 0.947 rs4666010 chr2:27878686 T/C cg27432699 chr2:27873401 GPN1 0.51 7.87 0.39 4.73e-14 Nonalcoholic fatty liver disease; LIHC cis rs11888559 0.655 rs13431510 chr2:203989347 G/A cg24605529 chr2:203879461 NBEAL1 0.81 6.13 0.31 2.47e-9 Height; LIHC cis rs17685 0.753 rs6976532 chr7:75681094 A/G cg04610667 chr7:75704037 NA -0.34 -6.32 -0.32 8.13e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9640161 0.783 rs35435439 chr7:150063534 C/T cg21361702 chr7:150065534 REPIN1 0.54 7.42 0.37 9.49e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs847649 0.731 rs13222980 chr7:102703898 A/G cg18108683 chr7:102477205 FBXL13 0.42 6.21 0.32 1.52e-9 Morning vs. evening chronotype; LIHC cis rs763121 0.853 rs4821812 chr22:39075235 G/C cg06022373 chr22:39101656 GTPBP1 0.65 11.25 0.52 3.49e-25 Menopause (age at onset); LIHC cis rs1707322 0.929 rs785500 chr1:46593044 C/T cg03146154 chr1:46216737 IPP -0.45 -7.22 -0.36 3.36e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4474465 1.000 rs7929712 chr11:78158542 T/C cg02023728 chr11:77925099 USP35 0.34 6.11 0.31 2.67e-9 Alzheimer's disease (survival time); LIHC cis rs7095944 0.584 rs4962693 chr10:126424835 C/T cg20435097 chr10:126320824 FAM53B 0.38 6.4 0.33 5.03e-10 Asthma; LIHC cis rs2839186 0.585 rs2839154 chr21:47637760 C/T cg05896524 chr21:47604654 C21orf56 -0.39 -6.06 -0.31 3.54e-9 Testicular germ cell tumor; LIHC cis rs11628318 0.614 rs62007936 chr14:103198740 G/A cg12046867 chr14:103022105 NA 0.52 7.21 0.36 3.68e-12 Platelet count; LIHC cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.23 0.55 8.88e-29 Alzheimer's disease; LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.54 -7.78 -0.39 8.45e-14 Lymphocyte counts; LIHC cis rs1552244 0.572 rs3774208 chr3:10164722 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs17376456 0.741 rs7718842 chr5:93480568 G/A cg25358565 chr5:93447407 FAM172A 1.12 9.92 0.47 1.51e-20 Diabetic retinopathy; LIHC cis rs7633770 0.965 rs6804112 chr3:46686248 C/T cg11219411 chr3:46661640 NA 0.53 8.77 0.43 8.46e-17 Coronary artery disease; LIHC cis rs6088590 1.000 rs6087625 chr20:33342477 A/G cg08999081 chr20:33150536 PIGU -0.38 -5.87 -0.3 1.02e-8 Coronary artery disease; LIHC cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs10779751 0.649 rs1318348 chr1:11130418 A/G cg08854313 chr1:11322531 MTOR 0.67 10.14 0.48 2.69e-21 Body mass index; LIHC cis rs796364 1.000 rs4263095 chr2:200830137 A/C cg23649088 chr2:200775458 C2orf69 -0.47 -5.78 -0.3 1.66e-8 Schizophrenia; LIHC cis rs7224737 1.000 rs12603330 chr17:40290589 T/A cg20291162 chr17:40259547 DHX58 -0.4 -6.38 -0.33 5.88e-10 Fibrinogen levels; LIHC cis rs12744310 0.895 rs1892417 chr1:41779673 T/C cg03962019 chr1:41807865 NA 0.4 6.43 0.33 4.22e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs4595586 0.545 rs11615584 chr12:39409350 C/G cg26384229 chr12:38710491 ALG10B 0.53 6.35 0.32 6.86e-10 Morning vs. evening chronotype; LIHC cis rs2197308 0.565 rs4123923 chr12:37857684 T/C cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg02359409 chr6:42947317 PEX6 -0.47 -6.66 -0.34 1.06e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7208859 0.573 rs7222803 chr17:29119897 A/G cg14067834 chr17:29058358 SUZ12P 0.71 7.03 0.36 1.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2115536 1.000 rs2115536 chr15:80194247 C/T cg00225070 chr15:80189496 MTHFS 0.65 10.86 0.51 8.27e-24 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs2197308 0.765 rs7295711 chr12:37903631 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC trans rs2727020 0.553 rs4103567 chr11:49255389 C/T cg15704280 chr7:45808275 SEPT13 -0.6 -9.68 -0.46 9.24e-20 Coronary artery disease; LIHC cis rs4555082 0.874 rs2816625 chr14:105734565 G/A cg10792982 chr14:105748885 BRF1 0.46 6.08 0.31 3.14e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs4699052 0.662 rs1516732 chr4:104251154 A/T cg16532752 chr4:104119610 CENPE -0.37 -5.86 -0.3 1.08e-8 Testicular germ cell tumor; LIHC cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.15e-51 Menopause (age at onset); LIHC cis rs875971 0.862 rs10261398 chr7:65750164 A/G cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.03e-40 Aortic root size; LIHC cis rs8062405 1.000 rs62037369 chr16:28883841 C/T cg00204512 chr16:28754710 NA 0.36 6.43 0.33 4.28e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs79149102 0.579 rs7342591 chr15:75306863 C/T cg16226627 chr15:75307476 SCAMP5 -0.53 -9.81 -0.47 3.64e-20 Lung cancer; LIHC cis rs2075371 0.863 rs1421479 chr7:133949345 T/G cg20476274 chr7:133979776 SLC35B4 0.69 9.35 0.45 1.19e-18 Mean platelet volume; LIHC cis rs4332037 0.539 rs34809719 chr7:2028968 G/T cg23422044 chr7:1970798 MAD1L1 -0.62 -6.97 -0.35 1.59e-11 Bipolar disorder; LIHC cis rs73001065 0.551 rs79954596 chr19:19548643 T/G cg03709012 chr19:19516395 GATAD2A 0.93 10.45 0.49 2.21e-22 LDL cholesterol; LIHC cis rs1670533 1.000 rs10084890 chr4:1053934 C/G cg27284194 chr4:1044797 NA -0.59 -8.87 -0.43 4.01e-17 Recombination rate (females); LIHC cis rs2412488 0.893 rs6840530 chr4:54359726 C/T cg22241045 chr4:54363911 LNX1 0.47 7.65 0.38 2e-13 DNA methylation (variation); LIHC cis rs10751667 0.580 rs11246363 chr11:971667 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.27e-21 Alzheimer's disease (late onset); LIHC cis rs7903847 0.642 rs2275090 chr10:99148151 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs950776 0.518 rs56007453 chr15:78826239 T/C cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs796364 0.806 rs6435040 chr2:200861161 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.8 8.83 0.43 5.53e-17 Schizophrenia; LIHC cis rs11758351 1.000 rs74363821 chr6:26189524 G/C cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC trans rs11148252 0.553 rs9536219 chr13:53227301 C/T cg18335740 chr13:41363409 SLC25A15 0.57 10.21 0.48 1.58e-21 Lewy body disease; LIHC cis rs4631830 0.720 rs2843560 chr10:51512129 C/G cg16070123 chr10:51489643 NA 0.38 6.05 0.31 3.8e-9 Prostate-specific antigen levels; LIHC cis rs12477438 0.501 rs13008171 chr2:99743419 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs155076 1.000 rs261430 chr13:21865242 C/T cg14456004 chr13:21872349 NA -1.08 -11.55 -0.53 2.92e-26 White matter hyperintensity burden; LIHC cis rs708547 0.578 rs781665 chr4:57831461 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.47 7.02 0.35 1.2e-11 Response to bleomycin (chromatid breaks); LIHC cis rs6565180 1.000 rs8049108 chr16:30376486 A/G cg17640201 chr16:30407289 ZNF48 -0.74 -12.53 -0.56 6.87e-30 Tonsillectomy; LIHC cis rs1190552 0.761 rs3783374 chr14:102885469 C/G cg10241871 chr14:102965420 TECPR2 -0.39 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs66573146 0.572 rs66611116 chr4:6953270 A/G cg00086871 chr4:6988644 TBC1D14 0.8 6.06 0.31 3.61e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs34779708 0.931 rs7084196 chr10:35367161 T/C cg04310649 chr10:35416472 CREM -0.42 -5.78 -0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7940866 0.646 rs10894293 chr11:130824213 C/T cg12179176 chr11:130786555 SNX19 -0.69 -9.96 -0.47 1.11e-20 Schizophrenia; LIHC cis rs2033711 0.905 rs893186 chr19:58969179 C/A cg13877915 chr19:58951672 ZNF132 0.59 9.06 0.44 9.94e-18 Uric acid clearance; LIHC cis rs12586317 0.547 rs78609489 chr14:35497285 T/C cg16230307 chr14:35515116 FAM177A1 0.81 13.5 0.59 1.42e-33 Psoriasis; LIHC cis rs1878931 0.580 rs8062722 chr16:3409161 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.82 14.49 0.62 1.89e-37 Body mass index (adult); LIHC trans rs1728785 0.901 rs1631910 chr16:68603335 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.23 0.32 1.4e-9 Ulcerative colitis; LIHC trans rs3176789 0.647 rs7295897 chr12:9920876 A/T cg18988856 chr7:99425577 CYP3A43 0.19 6.15 0.32 2.14e-9 Lymphocyte percentage of white cells;Neutrophil percentage of white cells; LIHC cis rs3849570 1.000 rs11915016 chr3:81833966 G/A cg07356753 chr3:81810745 GBE1 -0.63 -10.59 -0.5 7.33e-23 Waist circumference;Body mass index; LIHC cis rs9811920 0.529 rs793442 chr3:99581062 A/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.75 -0.3 2e-8 Axial length; LIHC cis rs7917772 0.536 rs11191361 chr10:104411958 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.75 8.73 0.43 1.16e-16 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs12928939 0.517 rs9940234 chr16:71964805 C/T cg03805757 chr16:71968109 PKD1L3 -0.91 -13.05 -0.58 7.02e-32 Post bronchodilator FEV1; LIHC cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg11644478 chr21:40555479 PSMG1 -0.43 -6.74 -0.34 6.88e-11 Cognitive function; LIHC cis rs9311474 0.502 rs4687624 chr3:52563572 C/T cg10802521 chr3:52805072 NEK4 -0.38 -6.24 -0.32 1.31e-9 Electroencephalogram traits; LIHC cis rs8114671 0.869 rs1407202 chr20:33651967 C/T cg07148914 chr20:33460835 GGT7 -0.55 -8.17 -0.4 6.13e-15 Height; LIHC cis rs735396 1.000 rs1169309 chr12:121439192 G/T cg02403541 chr12:121454288 C12orf43 0.47 8.27 0.41 3.09e-15 N-glycan levels; LIHC cis rs8180040 1.000 rs1076394 chr3:47322781 G/A cg27129171 chr3:47204927 SETD2 -0.64 -10.72 -0.5 2.61e-23 Colorectal cancer; LIHC trans rs6600671 1.000 rs2185281 chr1:121179991 A/G cg09829573 chr1:144692074 NBPF9 -0.44 -7.95 -0.39 2.67e-14 Hip geometry; LIHC cis rs8114671 0.836 rs745849 chr20:33572178 G/A cg07148914 chr20:33460835 GGT7 -0.61 -9.27 -0.45 2.11e-18 Height; LIHC cis rs2016586 0.832 rs4820209 chr22:36104647 C/T cg26342177 chr22:36113512 APOL5 0.36 6.12 0.31 2.61e-9 Body mass index; LIHC cis rs9549367 0.664 rs9549689 chr13:113848387 G/A cg18105134 chr13:113819100 PROZ -0.79 -13.44 -0.59 2.35e-33 Platelet distribution width; LIHC cis rs8017423 0.900 rs11625870 chr14:90693396 C/T cg04374321 chr14:90722782 PSMC1 -0.74 -14.13 -0.61 4.85e-36 Mortality in heart failure; LIHC cis rs1789 0.839 rs9997068 chr4:15650990 T/C cg21123203 chr4:15471301 CC2D2A -0.46 -7.35 -0.37 1.48e-12 Blood protein levels; LIHC cis rs12594515 0.967 rs67854274 chr15:45990518 A/G cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12032009 chr15:62352934 VPS13C -0.38 -6.04 -0.31 4.02e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7208859 0.623 rs9890862 chr17:29125450 C/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1814175 0.817 rs7109440 chr11:49966296 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.05 -0.78 1.27e-71 Height; LIHC cis rs9303401 0.659 rs36093395 chr17:56957357 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.34 0.56 3.31e-29 Cognitive test performance; LIHC cis rs2455601 0.744 rs11042107 chr11:8905871 G/T cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -6.77 -0.34 5.62e-11 Schizophrenia; LIHC cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg07308232 chr7:1071921 C7orf50 -0.55 -9.04 -0.44 1.23e-17 Longevity;Endometriosis; LIHC cis rs734999 0.588 rs2260976 chr1:2527678 A/G cg18854424 chr1:2615690 NA -0.34 -7.3 -0.37 2.02e-12 Ulcerative colitis; LIHC cis rs1055129 0.560 rs9891076 chr17:73911715 C/T cg14829360 chr17:73884958 NA -0.39 -6.57 -0.33 1.88e-10 White matter hyperintensity burden; LIHC cis rs6691722 0.506 rs12030365 chr1:24739220 T/A cg18323236 chr1:24743029 NIPAL3 0.39 7.37 0.37 1.28e-12 Response to interferon beta in multiple sclerosis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22529720 chr7:139044624 LUC7L2 0.41 6.35 0.32 6.85e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs877282 0.685 rs56234340 chr10:781339 A/G cg22713356 chr15:30763199 NA 1.16 11.52 0.53 3.54e-26 Uric acid levels; LIHC cis rs6456156 0.565 rs12529959 chr6:167469292 T/C cg07741184 chr6:167504864 NA 0.29 6.88 0.35 2.92e-11 Primary biliary cholangitis; LIHC cis rs1046896 0.553 rs56775875 chr17:80831291 G/T cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.46 0.37 7.27e-13 Glycated hemoglobin levels; LIHC cis rs12079745 0.590 rs3766092 chr1:169273400 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 1.96e-11 QT interval; LIHC trans rs6733379 0.588 rs2193790 chr2:34445953 A/G cg06334093 chr6:139094587 CCDC28A -0.45 -6.12 -0.31 2.6e-9 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs7107174 1.000 rs2256187 chr11:77919768 G/A cg02023728 chr11:77925099 USP35 0.47 8.44 0.42 9.26e-16 Testicular germ cell tumor; LIHC cis rs1557765 0.527 rs4756887 chr11:17394597 T/G cg15432903 chr11:17409602 KCNJ11 0.44 6.71 0.34 7.93e-11 Body mass index;Social communication problems; LIHC cis rs12701220 0.655 rs6955290 chr7:1151066 A/G cg04025307 chr7:1156635 C7orf50 -0.55 -7.3 -0.37 2.01e-12 Bronchopulmonary dysplasia; LIHC cis rs1707322 1.000 rs1768818 chr1:46514286 G/C cg03146154 chr1:46216737 IPP -0.44 -7.16 -0.36 4.84e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11711311 1.000 rs9288983 chr3:113488699 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.15 0.44 5.3e-18 IgG glycosylation; LIHC cis rs3793683 0.825 rs3793674 chr10:134555773 C/T cg27286337 chr10:134555280 INPP5A -1.04 -19.85 -0.73 6.78e-59 Migraine; LIHC cis rs10751667 0.666 rs7394427 chr11:970405 G/A cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs60871478 0.579 rs56109762 chr7:925967 G/A cg05535760 chr7:792225 HEATR2 -0.82 -6.1 -0.31 2.82e-9 Cerebrospinal P-tau181p levels; LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs28374715 0.681 rs77187862 chr15:41619276 A/T cg18705301 chr15:41695430 NDUFAF1 -0.93 -11.54 -0.53 3.11e-26 Ulcerative colitis; LIHC cis rs9303401 0.659 rs16943326 chr17:57050365 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.34 0.55 3.55e-29 Cognitive test performance; LIHC cis rs9457247 0.663 rs2237274 chr6:167442995 C/G cg07741184 chr6:167504864 NA 0.26 5.97 0.31 5.91e-9 Crohn's disease; LIHC cis rs2066819 1.000 rs80317430 chr12:56727705 G/A cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs1400745 0.729 rs28472856 chr14:35332157 C/T cg05294307 chr14:35346193 BAZ1A -0.45 -7.51 -0.38 5.09e-13 Monocyte count; LIHC cis rs1728785 1.000 rs1170434 chr16:68606590 A/G cg02972257 chr16:68554789 NA -0.57 -6.51 -0.33 2.7e-10 Ulcerative colitis; LIHC cis rs7927592 0.913 rs10896330 chr11:68254998 A/G cg01657329 chr11:68192670 LRP5 -0.45 -5.89 -0.3 9.01e-9 Total body bone mineral density; LIHC cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg21724239 chr8:58056113 NA 0.5 6.6 0.34 1.58e-10 Developmental language disorder (linguistic errors); LIHC cis rs68170813 0.559 rs12537011 chr7:107027833 G/A cg02696742 chr7:106810147 HBP1 -0.5 -5.74 -0.3 2.1e-8 Coronary artery disease; LIHC cis rs7927771 0.800 rs35996350 chr11:47389223 A/G cg20135002 chr11:47629003 NA -0.52 -8.79 -0.43 7.64e-17 Subjective well-being; LIHC cis rs7552404 1.000 rs4646961 chr1:76217169 G/A cg10523679 chr1:76189770 ACADM 0.63 8.78 0.43 7.88e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg18357526 chr6:26021779 HIST1H4A 0.62 8.59 0.42 3.19e-16 Blood metabolite levels; LIHC trans rs7615952 0.800 rs2062773 chr3:125639648 T/C cg07211511 chr3:129823064 LOC729375 -0.84 -10.68 -0.5 3.74e-23 Blood pressure (smoking interaction); LIHC cis rs1799949 0.965 rs799917 chr17:41244936 G/A cg23758822 chr17:41437982 NA 0.95 18.21 0.7 2.7e-52 Menopause (age at onset); LIHC cis rs2050392 0.928 rs2250077 chr10:30702929 A/G cg25182066 chr10:30743637 MAP3K8 -0.46 -7.33 -0.37 1.73e-12 Inflammatory bowel disease; LIHC cis rs360798 0.512 rs11893131 chr2:63079528 C/A cg17519650 chr2:63277830 OTX1 0.43 6.76 0.34 5.85e-11 Coronary artery disease; LIHC cis rs7191439 0.858 rs8050715 chr16:88780923 C/G cg02389323 chr16:88786976 FAM38A 0.73 6.8 0.35 4.72e-11 Plateletcrit; LIHC cis rs35146811 0.807 rs10228764 chr7:99608029 A/G cg22906224 chr7:99728672 NA 0.42 5.99 0.31 5.21e-9 Coronary artery disease; LIHC cis rs1691799 0.867 rs1168297 chr12:66735644 T/C cg16791601 chr12:66731901 HELB -0.57 -13.85 -0.6 6.39e-35 White blood cell count (basophil); LIHC cis rs7508 0.511 rs371922 chr8:17900003 T/C cg04898035 chr8:17640624 MTUS1 -0.34 -5.87 -0.3 1.01e-8 Atrial fibrillation; LIHC trans rs3749237 0.964 rs1799845 chr3:49847623 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.64 9.79 0.47 4.03e-20 Resting heart rate; LIHC cis rs9549367 0.789 rs3794422 chr13:113893729 G/A cg18105134 chr13:113819100 PROZ -0.66 -11.33 -0.52 1.75e-25 Platelet distribution width; LIHC trans rs72634258 0.836 rs7545687 chr1:7997183 G/A cg27306034 chr1:155224863 FAM189B 0.53 6.32 0.32 7.99e-10 Inflammatory bowel disease; LIHC cis rs4671400 0.543 rs10178135 chr2:61485267 T/C cg14146966 chr2:61757674 XPO1 -0.37 -5.85 -0.3 1.15e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs9648428 0.515 rs4723485 chr7:36205242 G/T cg14708893 chr7:36124863 NA -0.4 -6.02 -0.31 4.38e-9 Obesity-related traits; LIHC trans rs11039798 0.688 rs8188953 chr11:48749201 A/T cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs11167764 0.895 rs9324865 chr5:141488792 T/C cg23435118 chr5:141488016 NDFIP1 -0.43 -5.98 -0.31 5.75e-9 Crohn's disease; LIHC cis rs12497850 0.765 rs12487580 chr3:49182932 G/A cg07636037 chr3:49044803 WDR6 0.88 15.46 0.64 2.85e-41 Parkinson's disease; LIHC cis rs11958404 0.932 rs113264420 chr5:157437779 T/C cg05962755 chr5:157440814 NA 0.99 11.5 0.53 4.32e-26 IgG glycosylation; LIHC cis rs1670533 1.000 rs6857085 chr4:1095920 C/A cg27284194 chr4:1044797 NA -0.61 -8.82 -0.43 5.83e-17 Recombination rate (females); LIHC cis rs7100689 0.646 rs7919380 chr10:82133380 C/T cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.24e-12 Post bronchodilator FEV1; LIHC cis rs17539620 0.519 rs871071 chr6:154837667 T/C cg17771515 chr6:154831774 CNKSR3 0.54 6.05 0.31 3.8e-9 Lipoprotein (a) levels; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg14984255 chr18:11908827 MPPE1 -0.39 -6.9 -0.35 2.57e-11 Neuroblastoma; LIHC cis rs6545883 0.965 rs11887205 chr2:61774473 T/G cg14146966 chr2:61757674 XPO1 0.47 8.17 0.4 6.2e-15 Tuberculosis; LIHC cis rs9457247 0.534 rs933243 chr6:167403873 A/C cg23791538 chr6:167370224 RNASET2 -0.72 -12.89 -0.57 3.03e-31 Crohn's disease; LIHC cis rs818427 0.929 rs153550 chr5:112234957 C/T cg07820702 chr5:112228657 REEP5 -0.36 -5.72 -0.3 2.28e-8 Total body bone mineral density; LIHC cis rs9818758 0.607 rs34566463 chr3:49245077 T/C cg00383909 chr3:49044727 WDR6 0.81 6.8 0.35 4.74e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9640161 0.750 rs4395803 chr7:150025367 A/C cg10018233 chr7:150070692 REPIN1 0.52 8.18 0.4 5.58e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs12286929 0.644 rs3793957 chr11:115095654 C/T cg04055981 chr11:115044050 NA 0.45 6.53 0.33 2.38e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2979489 0.891 rs2979511 chr8:30394968 G/A cg26383811 chr8:30366931 RBPMS -0.71 -11.72 -0.54 6.94e-27 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs3820068 0.603 rs1122387 chr1:15947282 T/C cg17385448 chr1:15911702 AGMAT 0.35 6.11 0.31 2.78e-9 Systolic blood pressure; LIHC cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg05590025 chr7:65112418 INTS4L2 -0.62 -6.82 -0.35 4.26e-11 Diabetic kidney disease; LIHC cis rs1476670 0.565 rs2428965 chr1:44502909 A/G cg00455333 chr1:45205373 KIF2C -0.38 -5.76 -0.3 1.91e-8 Eotaxin levels; LIHC cis rs6545883 0.868 rs28749199 chr2:61827052 A/G cg14146966 chr2:61757674 XPO1 0.46 7.75 0.39 1.02e-13 Tuberculosis; LIHC cis rs34779708 0.966 rs1545757 chr10:35445588 A/T cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.5 -0.46 3.7e-19 Bipolar disorder; LIHC cis rs7727544 0.735 rs272875 chr5:131674888 T/C cg24060327 chr5:131705240 SLC22A5 -0.56 -7.78 -0.39 8.42e-14 Blood metabolite levels; LIHC cis rs600806 0.778 rs518697 chr1:110014778 G/A cg02415029 chr1:110025642 ATXN7L2 -0.44 -5.75 -0.3 1.95e-8 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16288997 chr4:185395914 IRF2 -0.45 -6.18 -0.32 1.81e-9 Pancreatic cancer; LIHC cis rs4474465 0.646 rs10751297 chr11:78278567 C/T cg02023728 chr11:77925099 USP35 -0.34 -5.96 -0.31 6.37e-9 Alzheimer's disease (survival time); LIHC cis rs7412746 0.611 rs2864873 chr1:150814174 A/G cg18016565 chr1:150552671 MCL1 0.54 10.31 0.49 7.18e-22 Melanoma; LIHC cis rs3770081 1.000 rs74607112 chr2:86305534 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.58 8.72 0.43 1.21e-16 Facial emotion recognition (sad faces); LIHC cis rs1003719 0.788 rs2835588 chr21:38462716 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs2073300 1.000 rs12626013 chr20:23442215 G/A cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25978167 chr4:57301353 PAICS;PPAT 0.45 6.16 0.32 2.07e-9 Pancreatic cancer; LIHC cis rs17102884 0.506 rs11845397 chr14:75404587 G/A cg11812906 chr14:75593930 NEK9 -0.47 -7.97 -0.4 2.4e-14 Neuroticism; LIHC cis rs7523273 0.606 rs2724382 chr1:207928635 G/C cg22525895 chr1:207977042 MIR29B2 0.64 10.31 0.49 6.75e-22 Schizophrenia; LIHC cis rs1577917 0.727 rs2758840 chr6:86304625 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.98 -0.54 7.53e-28 Response to antipsychotic treatment; LIHC cis rs904251 0.828 rs1757178 chr6:37486310 C/T cg08126542 chr6:37504118 NA 0.41 6.6 0.34 1.61e-10 Cognitive performance; LIHC cis rs243505 0.732 rs3800949 chr7:148479648 A/T cg09806900 chr7:148480153 CUL1 -0.43 -6.51 -0.33 2.6200000000000003e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1949733 0.598 rs16842480 chr4:8535621 G/T cg11789530 chr4:8429930 ACOX3 -0.63 -9.02 -0.44 1.35e-17 Response to antineoplastic agents; LIHC cis rs7959452 0.558 rs1478464 chr12:69779789 G/C cg20891283 chr12:69753455 YEATS4 0.89 19.14 0.72 4.92e-56 Blood protein levels; LIHC cis rs12477438 0.501 rs12992218 chr2:99753834 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.5 0.77 1.86e-69 Chronic sinus infection; LIHC cis rs922107 0.738 rs10922664 chr1:90032940 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.75 -0.39 1.03e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7582180 0.627 rs2241811 chr2:101011724 C/T cg14675211 chr2:100938903 LONRF2 0.56 8.23 0.41 3.98e-15 Intelligence (multi-trait analysis); LIHC cis rs6665290 0.901 rs61834001 chr1:227197411 C/T cg10327440 chr1:227177885 CDC42BPA -1.19 -25.41 -0.81 8.99e-81 Myeloid white cell count; LIHC cis rs903552 1.000 rs12719737 chr15:101999126 C/G cg06707286 chr15:102010195 PCSK6 -0.41 -5.78 -0.3 1.67e-8 Diabetic kidney disease; LIHC cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg16414030 chr3:133502952 NA -0.4 -6.25 -0.32 1.2e-9 Iron status biomarkers; LIHC cis rs67311347 0.866 rs11712426 chr3:40330322 G/A cg13409248 chr3:40428643 ENTPD3 0.38 5.9 0.3 8.83e-9 Renal cell carcinoma; LIHC cis rs4911259 0.507 rs8118663 chr20:31398876 A/G cg13636640 chr20:31349939 DNMT3B 0.4 7.23 0.36 3.27e-12 Inflammatory bowel disease; LIHC cis rs11628318 0.614 rs12590775 chr14:103150623 A/G cg23461800 chr14:103021989 NA 0.38 5.72 0.3 2.38e-8 Platelet count; LIHC cis rs9911578 0.967 rs72628392 chr17:56506160 A/G cg12560992 chr17:57184187 TRIM37 -0.93 -16.24 -0.66 2.36e-44 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.967 rs11845329 chr14:90727749 C/T cg04374321 chr14:90722782 PSMC1 0.78 15.47 0.64 2.74e-41 Mortality in heart failure; LIHC cis rs72634258 0.554 rs12741937 chr1:7897622 A/T cg00864860 chr1:7907996 UTS2 0.64 5.84 0.3 1.21e-8 Inflammatory bowel disease; LIHC cis rs2991971 1.000 rs2991972 chr1:46013208 C/T cg15605315 chr1:45957053 TESK2 0.45 5.86 0.3 1.07e-8 High light scatter reticulocyte count; LIHC trans rs8073060 0.586 rs4796104 chr17:34046832 T/C cg19694781 chr19:47549865 TMEM160 1.22 12.75 0.57 9.9e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs380904 0.926 rs7842979 chr8:144601896 T/G cg20583945 chr8:144636462 GSDMD 0.68 9.5 0.46 3.76e-19 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs7264396 0.635 rs6060709 chr20:34536022 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -10.43 -0.49 2.63e-22 Total cholesterol levels; LIHC cis rs6570726 0.791 rs383841 chr6:145888329 G/T cg05347473 chr6:146136440 FBXO30 -0.39 -6.1 -0.31 2.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7208859 0.623 rs1061343 chr17:29114276 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2806561 0.606 rs218341 chr1:23294153 G/C cg12483005 chr1:23474871 LUZP1 0.4 6.14 0.32 2.23e-9 Height; LIHC cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg11644478 chr21:40555479 PSMG1 -0.45 -7.07 -0.36 9.03e-12 Cognitive function; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05178316 chr20:62661238 PRPF6 -0.39 -6.19 -0.32 1.71e-9 Calcium levels; LIHC cis rs2580764 0.678 rs2580765 chr2:55204028 A/C cg09592903 chr2:55203963 RTN4 0.76 14.2 0.61 2.58e-36 Mean platelet volume; LIHC cis rs7945718 0.839 rs10831911 chr11:12834858 C/T cg25843174 chr11:12811716 TEAD1 0.35 8.12 0.4 8.77e-15 Educational attainment (years of education); LIHC cis rs1552244 0.608 rs2075310 chr3:10067651 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.69 9.08 0.44 8.55e-18 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18652121 chr3:179322868 MRPL47;NDUFB5 0.56 7.9 0.39 3.96e-14 Pancreatic cancer; LIHC cis rs1801251 0.963 rs35395584 chr2:233573698 G/C cg08000102 chr2:233561755 GIGYF2 0.76 11.4 0.52 9.8e-26 Coronary artery disease; LIHC cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.16 18.07 0.7 1.04e-51 Gut microbiome composition (summer); LIHC cis rs7208859 0.562 rs11650923 chr17:29008167 G/A cg14067834 chr17:29058358 SUZ12P 0.62 6.09 0.31 3.04e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1552244 0.572 rs67227131 chr3:10172744 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.83 -8.08 -0.4 1.13e-14 Alzheimer's disease; LIHC cis rs13064411 0.696 rs9808893 chr3:113228444 G/A cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs8177253 1.000 rs6439439 chr3:133481498 G/T cg12373951 chr3:133503437 NA 0.69 12.38 0.56 2.54e-29 Iron status biomarkers; LIHC cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg08219700 chr8:58056026 NA 0.5 6.33 0.32 7.49e-10 Developmental language disorder (linguistic errors); LIHC cis rs4803468 1.000 rs9304593 chr19:41942875 A/C cg14132834 chr19:41945861 ATP5SL 0.43 6.24 0.32 1.32e-9 Height; LIHC cis rs2153535 0.580 rs1414340 chr6:8491139 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs6141769 0.542 rs6119939 chr20:31315153 T/C cg13636640 chr20:31349939 DNMT3B -0.32 -5.74 -0.3 2.08e-8 Subjective well-being; LIHC cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg20607798 chr8:58055168 NA 0.49 6.07 0.31 3.33e-9 Developmental language disorder (linguistic errors); LIHC cis rs4073582 0.576 rs556595 chr11:66058082 T/G cg14036092 chr11:66035641 RAB1B 0.41 6.16 0.32 2.02e-9 Gout; LIHC cis rs4728302 0.934 rs4129572 chr7:133636888 T/C cg10665199 chr7:133106180 EXOC4 -0.35 -5.86 -0.3 1.1e-8 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs2404602 1.000 rs2120107 chr15:76869789 A/G cg03037974 chr15:76606532 NA 0.67 12.66 0.56 2.21e-30 Blood metabolite levels; LIHC cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg24549020 chr5:56110836 MAP3K1 0.48 6.29 0.32 9.73e-10 Initial pursuit acceleration; LIHC cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg12751644 chr20:60527061 NA 0.47 7.88 0.39 4.38e-14 Obesity-related traits; LIHC cis rs798554 0.704 rs798512 chr7:2782592 C/G cg13628971 chr7:2884303 GNA12 0.41 6.37 0.33 5.97e-10 Height; LIHC cis rs6831352 0.959 rs6532796 chr4:100042242 C/T cg13256891 chr4:100009986 ADH5 -0.58 -6.21 -0.32 1.53e-9 Alcohol dependence; LIHC trans rs75804782 0.580 rs72987332 chr2:239362529 G/T cg01134436 chr17:81009848 B3GNTL1 0.86 7.22 0.36 3.31e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs6502050 0.835 rs8081949 chr17:80117490 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs7707921 0.767 rs226199 chr5:81572464 G/C cg15871215 chr5:81402204 ATG10 0.7 8.44 0.42 9.29e-16 Breast cancer; LIHC cis rs3015497 0.616 rs3825571 chr14:51052118 A/G cg09863266 chr14:51125203 SAV1 -0.37 -6.08 -0.31 3.13e-9 Mean platelet volume; LIHC cis rs61990749 0.597 rs12896026 chr14:78244436 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.73 -0.39 1.18e-13 Fibroblast growth factor basic levels; LIHC cis rs6815814 0.950 rs45588337 chr4:38807328 A/G cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC cis rs921968 0.541 rs7601872 chr2:219319885 C/G cg02176678 chr2:219576539 TTLL4 -0.56 -7.64 -0.38 2.23e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7412746 0.658 rs4970987 chr1:150949682 T/C cg17724175 chr1:150552817 MCL1 0.41 7.8 0.39 7.32e-14 Melanoma; LIHC cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg16049864 chr8:95962084 TP53INP1 -0.6 -11.47 -0.53 5.62e-26 Type 2 diabetes; LIHC cis rs8017423 0.967 rs8016385 chr14:90721946 G/A cg04374321 chr14:90722782 PSMC1 0.77 15.19 0.63 3.32e-40 Mortality in heart failure; LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg19500275 chr17:80737654 TBCD 0.52 7.58 0.38 3.2e-13 Glycated hemoglobin levels; LIHC cis rs7582180 0.764 rs10460478 chr2:100919735 G/A cg14675211 chr2:100938903 LONRF2 0.52 7.91 0.39 3.53e-14 Intelligence (multi-trait analysis); LIHC cis rs9486719 1.000 rs12205655 chr6:96891733 T/A cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17791867 chr7:112579927 C7orf60 0.45 6.07 0.31 3.34e-9 Pancreatic cancer; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.17 0.61 3.36e-36 Prudent dietary pattern; LIHC cis rs10751667 0.643 rs7479473 chr11:929111 C/T cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC trans rs9929218 0.551 rs2296409 chr16:68713730 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.89 19.76 0.73 1.63e-58 Colorectal cancer; LIHC cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg13047869 chr3:10149882 C3orf24 0.53 6.75 0.34 6.18e-11 Alzheimer's disease; LIHC cis rs2072438 0.503 rs1323474 chr9:123852859 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 5.95 0.31 6.82e-9 Rheumatoid arthritis; LIHC cis rs787274 1.000 rs813101 chr9:115532907 C/G cg13803584 chr9:115635662 SNX30 -0.57 -6.26 -0.32 1.15e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs11626933 1.000 rs11621007 chr14:90743967 G/A cg14092571 chr14:90743983 NA -0.9 -14.89 -0.63 5.31e-39 Gut microbiota (bacterial taxa); LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg11494091 chr17:61959527 GH2 0.44 8.08 0.4 1.11e-14 Prudent dietary pattern; LIHC cis rs6964587 0.967 rs12671991 chr7:91559481 T/C cg17063962 chr7:91808500 NA -1.02 -19.52 -0.73 1.47e-57 Breast cancer; LIHC cis rs10504073 0.565 rs35282337 chr8:49920994 G/A cg00325661 chr8:49890786 NA 0.39 9.55 0.46 2.5e-19 Blood metabolite ratios; LIHC cis rs4727027 0.680 rs6464941 chr7:148826352 A/G cg23583168 chr7:148888333 NA -0.72 -8.92 -0.43 2.93e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs765787 0.530 rs4331289 chr15:45515338 C/T cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs992157 0.661 rs10171839 chr2:219051314 C/T cg00012203 chr2:219082015 ARPC2 0.84 13.88 0.6 4.71e-35 Colorectal cancer; LIHC cis rs4589502 0.800 rs4776855 chr15:67202075 T/C cg12317470 chr15:67143691 NA -0.54 -6.97 -0.35 1.65e-11 Lung cancer (smoking interaction); LIHC cis rs7772486 0.875 rs10457795 chr6:146415665 A/G cg23711669 chr6:146136114 FBXO30 0.65 10.94 0.51 4.51e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg03517284 chr6:25882590 NA -0.53 -6.79 -0.34 5.11e-11 Intelligence (multi-trait analysis); LIHC cis rs7546668 0.947 rs4233538 chr1:15849855 G/T cg11706911 chr1:15910989 AGMAT 0.44 6.82 0.35 4.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs507080 1.000 rs507080 chr11:118549582 G/A cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.76e-9 Serum metabolite levels; LIHC cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg23205692 chr1:25664452 TMEM50A 0.4 6.58 0.34 1.79e-10 Erythrocyte sedimentation rate; LIHC cis rs2153535 0.580 rs1414351 chr6:8476634 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs2404602 0.735 rs4886493 chr15:76679026 A/G cg23625390 chr15:77176239 SCAPER -0.48 -7.93 -0.39 3.16e-14 Blood metabolite levels; LIHC cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg22800045 chr5:56110881 MAP3K1 0.66 8.42 0.41 1.05e-15 Initial pursuit acceleration; LIHC cis rs9914988 0.832 rs34267753 chr17:27157586 T/C cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs9814567 1.000 rs2373865 chr3:134291556 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.25 0.55 7.29e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12497850 0.931 rs4974082 chr3:48999323 G/A cg07636037 chr3:49044803 WDR6 0.9 16.03 0.65 1.61e-43 Parkinson's disease; LIHC cis rs651907 0.557 rs3094297 chr3:101399260 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.69 11.79 0.54 3.78e-27 Colorectal cancer; LIHC trans rs2727020 0.675 rs7929401 chr11:49350832 C/A cg15704280 chr7:45808275 SEPT13 -0.74 -10.66 -0.5 4.07e-23 Coronary artery disease; LIHC cis rs2576037 0.583 rs680018 chr18:44409167 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 9.85 0.47 2.63e-20 Personality dimensions; LIHC cis rs769267 0.930 rs4808964 chr19:19603692 A/C cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.01 -0.31 4.76e-9 Tonsillectomy; LIHC cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504073 0.626 rs9298106 chr8:50007508 T/G cg00325661 chr8:49890786 NA 0.31 7.03 0.36 1.16e-11 Blood metabolite ratios; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04872869 chr1:28908637 SNORA16A;SNHG12 0.43 6.81 0.35 4.27e-11 Cognitive function; LIHC cis rs2404602 0.647 rs7165053 chr15:76978918 A/G cg03037974 chr15:76606532 NA -0.61 -10.08 -0.48 4.34e-21 Blood metabolite levels; LIHC cis rs9303401 0.661 rs9902820 chr17:56637545 A/C cg05425664 chr17:57184151 TRIM37 -0.5 -7.37 -0.37 1.3e-12 Cognitive test performance; LIHC cis rs9486719 1.000 rs12190507 chr6:96898265 T/G cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.32e-12 Migraine;Coronary artery disease; LIHC cis rs2806561 0.765 rs1738468 chr1:23510850 T/G cg12483005 chr1:23474871 LUZP1 0.46 7.34 0.37 1.59e-12 Height; LIHC cis rs72627509 0.904 rs58408429 chr4:57769824 T/C cg26694713 chr4:57773883 REST 0.73 10.55 0.5 1e-22 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9457247 0.967 rs1211447 chr6:167381979 C/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.73 0.47 6.7e-20 Crohn's disease; LIHC cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg18252515 chr7:66147081 NA 1.29 17.13 0.68 6.01e-48 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03337784 chr13:41768818 KBTBD7 0.44 6.3 0.32 9.42e-10 Pancreatic cancer; LIHC cis rs2806561 0.704 rs2746560 chr1:23526279 G/A cg12483005 chr1:23474871 LUZP1 0.47 7.19 0.36 4.12e-12 Height; LIHC cis rs1707322 0.650 rs4553239 chr1:46150486 C/A cg03146154 chr1:46216737 IPP 0.6 10.2 0.48 1.65e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7918232 0.830 rs9833 chr10:27400861 G/A cg14442939 chr10:27389572 ANKRD26 0.74 7.06 0.36 9.19e-12 Breast cancer; LIHC cis rs1577917 0.771 rs2758844 chr6:86330115 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.24 -0.55 8.02e-29 Response to antipsychotic treatment; LIHC cis rs7187994 0.848 rs34139611 chr16:84772473 C/T cg07647771 chr16:84786436 USP10 -0.34 -6.12 -0.31 2.63e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs12458462 1.000 rs12458462 chr18:77472436 C/A cg11879182 chr18:77439856 CTDP1 0.81 13.47 0.59 1.77e-33 Monocyte count; LIHC cis rs8017423 0.967 rs4900030 chr14:90689813 T/A cg04374321 chr14:90722782 PSMC1 0.73 13.82 0.6 7.8e-35 Mortality in heart failure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04277470 chr13:41707106 KBTBD6 0.5 7.07 0.36 8.54e-12 Pancreatic cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13296214 chr12:9436248 LOC642846 -0.34 -6.7 -0.34 8.54e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1023500 0.505 rs134886 chr22:42673856 C/T cg00645731 chr22:42541494 CYP2D7P1 -0.35 -6.12 -0.31 2.56e-9 Schizophrenia; LIHC cis rs9814567 1.000 rs7428326 chr3:134251184 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4713118 0.516 rs4713142 chr6:28106347 T/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Parkinson's disease; LIHC cis rs9902453 0.902 rs4075014 chr17:28305674 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.71 11.83 0.54 2.6e-27 Coffee consumption (cups per day); LIHC trans rs12478296 1.000 rs56102931 chr2:243039936 A/G cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.95e-15 Obesity-related traits; LIHC cis rs9733 0.596 rs6686525 chr1:150635811 C/T cg18016565 chr1:150552671 MCL1 0.59 11.61 0.53 1.77e-26 Tonsillectomy; LIHC cis rs9790314 0.967 rs336541 chr3:161056698 A/C cg03342759 chr3:160939853 NMD3 -0.69 -8.39 -0.41 1.25e-15 Morning vs. evening chronotype; LIHC cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg15691649 chr6:25882328 NA -0.54 -7.75 -0.39 1.07e-13 Blood metabolite levels; LIHC cis rs8062405 1.000 rs55991577 chr16:28843025 C/T cg16576597 chr16:28551801 NUPR1 0.38 6.21 0.32 1.52e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4975616 0.869 rs465498 chr5:1325803 A/G cg07493874 chr5:1342172 CLPTM1L -0.65 -10.68 -0.5 3.58e-23 Lung cancer; LIHC cis rs7520050 0.808 rs11211195 chr1:46282295 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.93 0.31 7.33e-9 Red blood cell count;Reticulocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08367703 chr9:139304491 SDCCAG3;PMPCA 0.42 6.04 0.31 3.93e-9 Pancreatic cancer; LIHC cis rs250677 0.958 rs36067 chr5:148417553 T/G cg18129178 chr5:148520854 ABLIM3 -0.48 -6.49 -0.33 3.1e-10 Breast cancer; LIHC cis rs922107 0.738 rs12740865 chr1:90035179 G/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.74 -0.39 1.17e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs17685 0.753 rs6953665 chr7:75769049 C/T cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10489202 1.000 rs4657727 chr1:167965241 T/C cg24449463 chr1:168025552 DCAF6 -0.53 -6.72 -0.34 7.5e-11 Schizophrenia; LIHC cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.7 0.57 1.57e-30 Total body bone mineral density; LIHC cis rs8084351 0.512 rs4939727 chr18:50792914 C/T cg24270629 chr18:50823537 DCC -0.48 -7.24 -0.36 2.92e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2239547 0.522 rs6445550 chr3:52983434 G/A cg11645453 chr3:52864694 ITIH4 0.23 5.75 0.3 1.96e-8 Schizophrenia; LIHC cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg03060546 chr3:49711283 APEH 0.45 6.76 0.34 5.88e-11 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs2073300 1.000 rs6114142 chr20:23461082 A/G cg16736954 chr20:23401023 NAPB 0.49 5.73 0.3 2.18e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2303759 0.914 rs2288481 chr19:49878196 G/A cg22307029 chr19:49891270 CCDC155 0.57 8.97 0.44 1.98e-17 Multiple sclerosis; LIHC trans rs2243480 0.901 rs13237344 chr7:66022256 T/A cg07424592 chr7:64974309 NA 0.78 8.94 0.44 2.44e-17 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs160652 chr7:65538431 A/G cg05590025 chr7:65112418 INTS4L2 -0.56 -6.05 -0.31 3.91e-9 Diabetic kidney disease; LIHC cis rs1866706 0.896 rs6486062 chr11:12860618 C/T cg25843174 chr11:12811716 TEAD1 -0.33 -6.99 -0.35 1.41e-11 Intelligence (multi-trait analysis); LIHC cis rs700651 0.821 rs770661 chr2:198725444 A/G cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Intracranial aneurysm; LIHC cis rs72781680 0.611 rs72783636 chr2:24328706 C/T cg06627628 chr2:24431161 ITSN2 -0.65 -7.6 -0.38 2.84e-13 Lymphocyte counts; LIHC cis rs2073300 0.609 rs6137915 chr20:23358509 A/G cg16736954 chr20:23401023 NAPB -0.71 -8.3 -0.41 2.47e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg18305652 chr10:134549665 INPP5A 0.46 6.7 0.34 8.83e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.89 7.71 0.38 1.35e-13 Platelet count; LIHC cis rs910316 0.870 rs7147712 chr14:75670707 C/G cg08847533 chr14:75593920 NEK9 -0.77 -15.23 -0.64 2.5e-40 Height; LIHC cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg00149659 chr3:10157352 C3orf10 0.61 6.71 0.34 7.86e-11 Alzheimer's disease; LIHC cis rs1403694 0.695 rs3821815 chr3:186434262 A/G cg12454167 chr3:186435060 KNG1 0.38 8.93 0.44 2.59e-17 Blood protein levels; LIHC trans rs7246657 0.943 rs13345116 chr19:37847098 A/T cg24637308 chr11:6592297 DNHD1 0.43 6.09 0.31 2.99e-9 Coronary artery calcification; LIHC cis rs4253772 0.591 rs6008361 chr22:46652372 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.71 -6.53 -0.33 2.33e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs8180040 0.903 rs13094438 chr3:47277885 G/A cg02527881 chr3:46936655 PTH1R -0.32 -6.22 -0.32 1.43e-9 Colorectal cancer; LIHC cis rs6456156 0.528 rs6936261 chr6:167469676 A/C cg23791538 chr6:167370224 RNASET2 -0.61 -10.45 -0.49 2.32e-22 Primary biliary cholangitis; LIHC cis rs9596863 0.898 rs68056413 chr13:54375907 G/T ch.13.53330881F chr13:54432880 NA 0.43 5.78 0.3 1.69e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11376330 chr3:49131570 QRICH1 0.47 6.24 0.32 1.27e-9 Lung function (FEV1/FVC); LIHC cis rs13392177 0.660 rs62185964 chr2:219073745 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.55 -7.82 -0.39 6.54e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg15691649 chr6:25882328 NA -0.4 -6.22 -0.32 1.44e-9 Height; LIHC cis rs1018836 0.631 rs2205157 chr8:91472384 C/T cg16814680 chr8:91681699 NA -0.36 -5.9 -0.3 8.98e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs35306767 0.715 rs17221456 chr10:1037234 T/C cg20503657 chr10:835505 NA 0.86 8.04 0.4 1.45e-14 Eosinophil percentage of granulocytes; LIHC cis rs61656020 1 rs61656020 chr16:1882221 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.71 -9.41 -0.45 7.56e-19 Ankle injury; LIHC cis rs758324 0.947 rs58016983 chr5:131235275 T/C cg06307176 chr5:131281290 NA -0.42 -6.15 -0.32 2.12e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs11229555 0.609 rs12291791 chr11:58186290 C/T cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2242116 0.796 rs9852082 chr3:46972377 T/C cg16586182 chr3:47516702 SCAP -0.39 -6.63 -0.34 1.27e-10 Birth weight; LIHC cis rs367615 0.704 rs72802966 chr5:108846754 T/G cg17395555 chr5:108820864 NA 0.4 8.66 0.42 1.96e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs1577917 1.000 rs12215037 chr6:86727631 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.04 -0.48 5.87e-21 Response to antipsychotic treatment; LIHC cis rs8084351 0.512 rs4939728 chr18:50793071 C/T cg24270629 chr18:50823537 DCC 0.51 7.72 0.39 1.3e-13 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs929354 0.739 rs12533082 chr7:157014172 T/A cg05182265 chr7:156933206 UBE3C -0.33 -6.28 -0.32 1.01e-9 Body mass index; LIHC cis rs4845459 0.967 rs10888503 chr1:152593549 C/T cg20634798 chr1:152595351 LCE3A -0.3 -5.76 -0.3 1.84e-8 Psoriasis; LIHC cis rs7044106 0.791 rs10985009 chr9:123493039 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.58 -9.17 -0.44 4.55e-18 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC trans rs2727020 0.595 rs10839281 chr11:49483373 A/C cg03929089 chr4:120376271 NA -0.88 -17.6 -0.69 7.7e-50 Coronary artery disease; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg14004847 chr7:1930337 MAD1L1 0.49 7.39 0.37 1.14e-12 Bipolar disorder and schizophrenia; LIHC cis rs1707322 1.000 rs10890376 chr1:46406582 C/T cg03146154 chr1:46216737 IPP 0.48 7.7 0.38 1.51e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11864453 0.826 rs2240243 chr16:72137561 A/G cg01557791 chr16:72042693 DHODH 0.54 8.85 0.43 4.81e-17 Fibrinogen levels; LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg02993280 chr1:107599747 PRMT6 -0.63 -9.87 -0.47 2.26e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg14671364 chr1:107599128 PRMT6 -0.5 -7.39 -0.37 1.11e-12 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9910055 0.571 rs10208 chr17:42300278 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.36 6.44 0.33 4e-10 Total body bone mineral density; LIHC cis rs4803468 1.000 rs11883104 chr19:41923799 T/C cg09537434 chr19:41945824 ATP5SL -1.02 -21.47 -0.76 2.42e-65 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16141690 chr14:23563715 C14orf119;ACIN1 0.47 7.21 0.36 3.64e-12 Cognitive function; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg00656387 chr3:40428638 ENTPD3 0.48 7.95 0.4 2.66e-14 Renal cell carcinoma; LIHC trans rs7618501 1.000 rs3749241 chr3:49744392 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.72 -0.62 2.56e-38 Intelligence (multi-trait analysis); LIHC cis rs700651 0.752 rs7592556 chr2:198891021 G/A cg10820045 chr2:198174542 NA 0.45 6.82 0.35 4.03e-11 Intracranial aneurysm; LIHC cis rs4268898 0.610 rs55860688 chr2:24451534 T/C cg06627628 chr2:24431161 ITSN2 -0.73 -9.76 -0.47 5.02e-20 Asthma; LIHC cis rs12594515 0.506 rs74199860 chr15:45989190 C/T cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.78e-19 Waist circumference;Weight; LIHC cis rs12220238 1.000 rs10824085 chr10:75911984 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.58 0.34 1.78e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7635838 0.859 rs9869977 chr3:11480081 C/A cg00170343 chr3:11313890 ATG7 0.44 6.87 0.35 3.11e-11 HDL cholesterol; LIHC cis rs1577917 0.771 rs9450319 chr6:86427325 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 10.31 0.49 6.95e-22 Response to antipsychotic treatment; LIHC cis rs34779708 0.966 rs12769575 chr10:35435927 A/T cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11676348 0.755 rs1008562 chr2:219026972 G/C cg00012203 chr2:219082015 ARPC2 0.57 7.67 0.38 1.87e-13 Ulcerative colitis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25517427 chr17:12921477 ELAC2 -0.45 -6.38 -0.33 5.61e-10 Systolic blood pressure; LIHC cis rs66887589 0.616 rs6843509 chr4:120220196 G/A cg09307838 chr4:120376055 NA 0.53 7.86 0.39 5.07e-14 Diastolic blood pressure; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg12038521 chr19:2111714 AP3D1 0.43 6.36 0.33 6.61e-10 Bilirubin levels; LIHC cis rs79057730 0.599 rs79272827 chr7:807015 C/G cg11064039 chr7:766100 PRKAR1B;HEATR2 0.87 9.93 0.47 1.42e-20 Initial pursuit acceleration; LIHC cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg19318889 chr4:1322082 MAEA -0.47 -7.74 -0.39 1.14e-13 Obesity-related traits; LIHC trans rs1704198 1.000 rs2664689 chr1:213897431 C/T cg02442787 chr4:139230014 NA 0.41 6.32 0.32 8.23e-10 Obesity; LIHC cis rs7312933 0.737 rs10880261 chr12:42573822 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.82 0.39 6.59e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7824557 0.767 rs6985146 chr8:11170721 A/C cg21775007 chr8:11205619 TDH 0.45 6.61 0.34 1.46e-10 Retinal vascular caliber; LIHC cis rs8005677 1.000 rs4982706 chr14:23381697 C/T cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26770187 chr3:14693171 C3orf19 0.48 7.18 0.36 4.31e-12 Pancreatic cancer; LIHC cis rs801193 0.660 rs4610622 chr7:66224497 T/C cg18252515 chr7:66147081 NA -0.44 -6.39 -0.33 5.46e-10 Aortic root size; LIHC cis rs4466137 0.830 rs6886442 chr5:82973210 A/C cg16102102 chr5:83017553 HAPLN1 0.43 6.8 0.35 4.54e-11 Prostate cancer; LIHC cis rs2404602 0.692 rs4383105 chr15:77055510 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.7e-9 Blood metabolite levels; LIHC cis rs748404 0.697 rs505249 chr15:43559960 T/A cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.96 0.4 2.61e-14 Lung cancer; LIHC cis rs875971 0.895 rs4145009 chr7:65726615 T/C cg11764359 chr7:65958608 NA -0.81 -13.63 -0.59 4.22e-34 Aortic root size; LIHC cis rs1165668 0.755 rs2583283 chr12:104313643 G/A cg21863207 chr12:104234989 NT5DC3 0.46 8.02 0.4 1.69e-14 Coronary heart disease (SNP X SNP interaction); LIHC cis rs16828019 0.852 rs11209545 chr1:41576357 T/G cg20697417 chr1:41786797 NA 0.32 6.12 0.31 2.52e-9 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.586 rs67077657 chr3:161138521 A/G cg03342759 chr3:160939853 NMD3 -0.55 -8.36 -0.41 1.62e-15 Morning vs. evening chronotype; LIHC cis rs965469 1.000 rs6051792 chr20:3343519 T/C cg25506879 chr20:3388711 C20orf194 -0.54 -6.53 -0.33 2.33e-10 IFN-related cytopenia; LIHC cis rs12477438 0.520 rs11883676 chr2:99800814 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.21 0.61 2.47e-36 Chronic sinus infection; LIHC cis rs3806843 0.771 rs2563336 chr5:140107199 A/G cg26395211 chr5:140044315 WDR55 0.41 5.92 0.31 7.66e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg05834845 chr3:195489306 MUC4 0.65 9.78 0.47 4.53e-20 Lung disease severity in cystic fibrosis; LIHC trans rs1814175 0.817 rs1390676 chr11:50056778 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.01 0.35 1.3e-11 Height; LIHC cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg09913183 chr17:42254507 C17orf65;ASB16 -0.66 -10.09 -0.48 3.81e-21 Total body bone mineral density; LIHC cis rs1552244 0.572 rs113406084 chr3:10170190 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC cis rs4716602 0.596 rs12386682 chr7:156158265 C/T cg16983916 chr7:156159713 NA -0.32 -5.84 -0.3 1.22e-8 Anti-saccade response; LIHC cis rs74544699 1.000 rs11574452 chr4:74846661 A/C cg16072462 chr4:74847758 PF4 -0.59 -6.32 -0.32 8.28e-10 Growth-regulated protein alpha levels; LIHC cis rs2625529 0.824 rs12906711 chr15:72215065 A/G cg16672083 chr15:72433130 SENP8 -0.31 -5.8 -0.3 1.48e-8 Red blood cell count; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg23131131 chr22:24373011 LOC391322 -0.7 -10.22 -0.48 1.47e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs941873 0.803 rs5015119 chr10:81101609 G/C cg11057378 chr10:81107060 PPIF 0.35 5.84 0.3 1.23e-8 Height; LIHC trans rs947612 0.576 rs9342991 chr6:73683775 G/A cg13494037 chr12:24737079 C12orf67 0.36 6.04 0.31 4e-9 HIV-1 viral setpoint;Body mass index; LIHC cis rs7100689 0.577 rs873395 chr10:82037215 C/T cg01528321 chr10:82214614 TSPAN14 -0.88 -12.14 -0.55 1.84e-28 Post bronchodilator FEV1; LIHC cis rs9399135 0.967 rs17638970 chr6:135320063 A/G cg22676075 chr6:135203613 NA 0.38 6.29 0.32 9.78e-10 Red blood cell count; LIHC cis rs17376456 0.825 rs10054903 chr5:93281491 C/A cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs35110281 0.627 rs7283362 chr21:44973667 C/G cg04455712 chr21:45112962 RRP1B 0.4 6.65 0.34 1.15e-10 Mean corpuscular volume; LIHC cis rs61990749 0.597 rs6574391 chr14:78208121 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.12 0.48 3.09e-21 Fibroblast growth factor basic levels; LIHC cis rs7103648 0.897 rs2278890 chr11:47399602 G/A cg20307385 chr11:47447363 PSMC3 0.85 12.32 0.55 4.17e-29 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs2836950 0.501 rs13047518 chr21:40707307 G/A cg06238570 chr21:40685208 BRWD1 -0.47 -7.52 -0.38 4.74e-13 Menarche (age at onset); LIHC cis rs11626933 1.000 rs3742669 chr14:90767746 C/A cg04374321 chr14:90722782 PSMC1 -0.49 -6.85 -0.35 3.51e-11 Gut microbiota (bacterial taxa); LIHC cis rs35110281 0.693 rs11089093 chr21:45121161 C/T cg04455712 chr21:45112962 RRP1B 0.47 8.36 0.41 1.56e-15 Mean corpuscular volume; LIHC cis rs1577917 1.000 rs68171315 chr6:86707400 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.71 -0.34 8.01e-11 Response to antipsychotic treatment; LIHC cis rs240764 0.817 rs6907240 chr6:101153782 T/C cg09795085 chr6:101329169 ASCC3 -0.52 -7.21 -0.36 3.57e-12 Neuroticism; LIHC cis rs17253792 0.822 rs74935793 chr14:56143277 G/A cg01858014 chr14:56050164 KTN1 -0.7 -7.28 -0.37 2.32e-12 Putamen volume; LIHC cis rs79387448 0.745 rs1989399 chr2:103166742 G/A cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs1144333 0.655 rs1361487 chr1:76430471 A/C cg22875332 chr1:76189707 ACADM 0.4 5.94 0.31 6.85e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs3731827 0.511 rs72843872 chr2:85820027 A/G cg11108890 chr2:85811471 VAMP5 0.45 5.81 0.3 1.43e-8 Prostate cancer; LIHC cis rs2073300 1.000 rs79169006 chr20:23443535 A/T cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2361718 0.967 rs2361719 chr17:78103403 A/G cg09238746 chr17:78121135 EIF4A3 0.45 6.58 0.34 1.78e-10 Yeast infection; LIHC cis rs17106184 0.892 rs12070594 chr1:51136876 C/A cg07174182 chr1:51127561 FAF1 -0.74 -8.19 -0.4 5.42e-15 Type 2 diabetes; LIHC cis rs9733 0.526 rs11204698 chr1:150659545 G/A cg13175981 chr1:150552382 MCL1 -0.44 -5.99 -0.31 5.37e-9 Tonsillectomy; LIHC cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg03264133 chr6:25882463 NA -0.64 -9.14 -0.44 5.72e-18 Blood metabolite levels; LIHC cis rs6089584 0.821 rs4925332 chr20:60604639 C/T cg06108461 chr20:60628389 TAF4 -0.96 -15.88 -0.65 6.13e-43 Body mass index; LIHC cis rs2404602 0.536 rs7165025 chr15:76766434 G/A cg23625390 chr15:77176239 SCAPER 0.36 5.79 0.3 1.59e-8 Blood metabolite levels; LIHC cis rs796364 0.756 rs2949006 chr2:200715388 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 8.79 0.43 7.68e-17 Schizophrenia; LIHC cis rs2237234 0.580 rs7763910 chr6:26472655 C/T cg09904177 chr6:26538194 HMGN4 -0.44 -7.35 -0.37 1.51e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs11105298 0.891 rs11105318 chr12:89926658 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.54 -6.34 -0.32 7.36e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7618501 0.519 rs3774750 chr3:50208406 C/G cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.46 -6.72 -0.34 7.56e-11 Intelligence (multi-trait analysis); LIHC cis rs651907 0.557 rs13099674 chr3:101489629 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.8 0.54 3.46e-27 Colorectal cancer; LIHC cis rs5769765 0.728 rs6520064 chr22:50294469 A/G cg26441486 chr22:50317300 CRELD2 0.35 6.29 0.32 9.46e-10 Schizophrenia; LIHC cis rs6977660 0.714 rs10270204 chr7:19819544 C/T cg07541023 chr7:19748670 TWISTNB 0.4 5.97 0.31 5.9e-9 Thyroid stimulating hormone; LIHC cis rs34172651 0.517 rs3803716 chr16:24802325 C/T cg04756594 chr16:24857601 SLC5A11 0.6 9.02 0.44 1.38e-17 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs62271514 chr3:134298554 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.16 0.32 2.05e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs651907 0.557 rs12629658 chr3:101356535 A/G cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.11 -0.31 2.64e-9 Colorectal cancer; LIHC cis rs1030268 0.607 rs34218501 chr7:133210375 G/A cg03336402 chr7:133662267 EXOC4 -0.5 -5.97 -0.31 5.89e-9 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.706 rs57933226 chr17:37412829 C/T cg07936489 chr17:37558343 FBXL20 -0.85 -12.37 -0.56 2.74e-29 Glomerular filtration rate (creatinine); LIHC trans rs3783890 1.000 rs11621025 chr14:93740831 A/G cg02802420 chr16:69363236 PDF;COG8 0.33 6.32 0.32 8.07e-10 Body mass index; LIHC cis rs2997447 0.706 rs17184877 chr1:26443908 A/T cg19633962 chr1:26362018 EXTL1 -0.65 -5.98 -0.31 5.59e-9 QRS complex (12-leadsum); LIHC trans rs916888 0.773 rs199443 chr17:44819565 C/T cg26692224 chr17:62915920 LRRC37A3 -0.71 -6.87 -0.35 2.97e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4668356 0.773 rs57335774 chr2:172031967 T/G cg13882835 chr2:172017928 TLK1 0.45 6.02 0.31 4.41e-9 Cognitive performance; LIHC cis rs11690935 0.918 rs12692978 chr2:172725981 C/T cg13550731 chr2:172543902 DYNC1I2 -0.97 -17.51 -0.69 1.92e-49 Schizophrenia; LIHC cis rs2806561 0.704 rs636940 chr1:23522967 A/T cg11953164 chr1:23521307 HTR1D 0.29 5.78 0.3 1.68e-8 Height; LIHC cis rs9916302 0.861 rs4795377 chr17:37669056 C/T cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC cis rs1664789 0.844 rs1616049 chr5:53281118 T/A ch.5.1024479R chr5:53302184 ARL15 0.54 8.76 0.43 9.22e-17 Waist circumference adjusted for body mass index; LIHC cis rs6582630 0.519 rs8189618 chr12:38276281 A/C cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.57e-21 Drug-induced liver injury (flucloxacillin); LIHC cis rs9814567 1.000 rs9841212 chr3:134191938 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.55 -10.46 -0.49 2.16e-22 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs72781680 1.000 rs72796327 chr2:24140372 T/C cg08917208 chr2:24149416 ATAD2B 0.88 7.8 0.39 7.33e-14 Lymphocyte counts; LIHC cis rs4555082 0.874 rs2735828 chr14:105710486 C/A cg06808227 chr14:105710500 BRF1 -0.64 -9.0 -0.44 1.56e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg11890956 chr21:40555474 PSMG1 1.03 14.59 0.62 7.75e-38 Cognitive function; LIHC trans rs11098499 0.954 rs10014845 chr4:120301077 T/G cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs7769051 1.000 rs12203977 chr6:133122760 A/G cg22852734 chr6:133119734 C6orf192 0.92 9.45 0.46 5.52e-19 Type 2 diabetes nephropathy; LIHC cis rs4906332 1.000 rs12892062 chr14:103883512 A/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.28 -0.32 1.04e-9 Coronary artery disease; LIHC cis rs4727027 0.901 rs7794500 chr7:148819519 C/T cg23583168 chr7:148888333 NA 0.68 9.59 0.46 1.89e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs965469 1.000 rs6051809 chr20:3352551 A/C cg25506879 chr20:3388711 C20orf194 -0.54 -6.44 -0.33 4.02e-10 IFN-related cytopenia; LIHC trans rs2270927 0.510 rs35966882 chr5:75577716 A/G cg13563193 chr19:33072644 PDCD5 1.03 10.06 0.48 5.03e-21 Mean corpuscular volume; LIHC cis rs1577917 0.771 rs2842609 chr6:86296788 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.86 -0.39 4.92e-14 Response to antipsychotic treatment; LIHC cis rs600806 0.850 rs11102981 chr1:109967323 G/C cg16275483 chr1:110013120 SYPL2 -0.49 -6.04 -0.31 4.11e-9 Intelligence (multi-trait analysis); LIHC cis rs2576037 0.526 rs1789152 chr18:44433092 G/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.73e-12 Personality dimensions; LIHC cis rs10256972 0.933 rs35696159 chr7:1047194 A/G cg16145915 chr7:1198662 ZFAND2A -0.29 -7.09 -0.36 7.83e-12 Longevity;Endometriosis; LIHC cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg03264133 chr6:25882463 NA 0.88 12.43 0.56 1.59e-29 Blood metabolite levels; LIHC cis rs12594515 1.000 rs6493170 chr15:45987019 G/A cg19682013 chr15:45996608 NA 0.41 7.25 0.37 2.76e-12 Waist circumference;Weight; LIHC cis rs4803468 1.000 rs2288871 chr19:41917868 C/T cg14132834 chr19:41945861 ATP5SL -0.43 -6.41 -0.33 4.8e-10 Height; LIHC trans rs7246657 0.943 rs8106839 chr19:37958475 C/G cg10208301 chr11:6592745 DNHD1 0.47 6.45 0.33 3.74e-10 Coronary artery calcification; LIHC cis rs2637266 1.000 rs1907298 chr10:78329928 A/T cg18941641 chr10:78392320 NA 0.28 5.96 0.31 6.31e-9 Pulmonary function; LIHC cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg03806693 chr22:41940476 POLR3H -1.06 -12.43 -0.56 1.56e-29 Vitiligo; LIHC cis rs7618501 0.699 rs1317154 chr3:49910084 T/C cg21467203 chr3:49911342 NA -0.49 -8.59 -0.42 3.2e-16 Intelligence (multi-trait analysis); LIHC cis rs853679 0.517 rs9380055 chr6:28081629 A/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs12950390 0.853 rs17773010 chr17:45858297 C/T cg03474202 chr17:45855739 NA -0.35 -5.99 -0.31 5.39e-9 IgG glycosylation; LIHC cis rs6586163 0.872 rs7082720 chr10:90742049 C/T cg03111039 chr10:90751583 FAS;ACTA2 -0.53 -7.78 -0.39 8.86e-14 Chronic lymphocytic leukemia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10566763 chr6:106773518 ATG5 -0.39 -6.1 -0.31 2.86e-9 Pancreatic cancer; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg00656387 chr3:40428638 ENTPD3 -0.5 -8.54 -0.42 4.44e-16 Renal cell carcinoma; LIHC cis rs4773330 1.000 rs4773330 chr13:111818832 A/G cg26911804 chr13:111806221 ARHGEF7 0.65 6.36 0.33 6.53e-10 Bilirubin levels; LIHC cis rs4820539 0.966 rs3788350 chr22:23468468 C/T cg21100191 chr22:23484243 RTDR1 0.86 14.94 0.63 3.25e-39 Bone mineral density; LIHC cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.79 -0.34 5.07e-11 Gut microbiome composition (summer); LIHC cis rs4665809 1.000 rs4665823 chr2:26312723 A/G cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.02e-15 Gut microbiome composition (summer); LIHC cis rs6546550 0.869 rs6712827 chr2:70156540 C/G cg02498382 chr2:70120550 SNRNP27 -0.43 -7.48 -0.37 6.34e-13 Prevalent atrial fibrillation; LIHC trans rs3780486 0.846 rs913214 chr9:33135085 G/A cg04842962 chr6:43655489 MRPS18A 1.08 25.4 0.81 1.05e-80 IgG glycosylation; LIHC cis rs7589728 0.620 rs76687350 chr2:88473832 G/A cg07952391 chr2:88470173 THNSL2 0.85 8.13 0.4 8.16e-15 Plasma clusterin levels; LIHC cis rs1577917 0.740 rs2758842 chr6:86308731 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.47 -9.17 -0.44 4.43e-18 Response to antipsychotic treatment; LIHC cis rs644799 1.000 rs534497 chr11:95562868 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.31 0.68 1.13e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6596100 0.538 rs56097052 chr5:132194430 A/G cg02081065 chr5:132209139 LEAP2 0.27 6.11 0.31 2.69e-9 Breast cancer; LIHC cis rs7107174 1.000 rs2511177 chr11:77922960 C/T cg02023728 chr11:77925099 USP35 0.42 8.0 0.4 1.99e-14 Testicular germ cell tumor; LIHC cis rs539514 0.587 rs7320602 chr13:76332868 A/G cg04757411 chr13:76259545 LMO7 -0.4 -6.71 -0.34 8.23e-11 Type 1 diabetes; LIHC cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs9640161 0.789 rs10282458 chr7:150045302 C/T cg10018233 chr7:150070692 REPIN1 0.52 8.4 0.41 1.24e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs35110281 0.840 rs2838331 chr21:45026728 A/G cg01579765 chr21:45077557 HSF2BP 0.35 6.43 0.33 4.22e-10 Mean corpuscular volume; LIHC cis rs6089829 0.962 rs2277769 chr20:61666805 C/T cg03213289 chr20:61660250 NA 0.51 9.35 0.45 1.16e-18 Prostate cancer (SNP x SNP interaction); LIHC cis rs7131987 0.868 rs10771508 chr12:29414211 G/A cg05697976 chr12:29376483 FAR2 0.33 6.76 0.34 6.05e-11 QT interval; LIHC cis rs1200821 0.535 rs1208784 chr10:37768433 A/G cg25427524 chr10:38739819 LOC399744 -0.41 -6.91 -0.35 2.43e-11 Hemostatic factors and hematological phenotypes; LIHC cis rs9596863 0.898 rs7328896 chr13:54334206 A/T ch.13.53330881F chr13:54432880 NA 0.44 6.11 0.31 2.77e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs311392 1.000 rs2671804 chr8:55088853 C/T cg20636351 chr8:55087400 NA -0.4 -8.07 -0.4 1.16e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs7712401 0.755 rs965821 chr5:122137708 A/G cg18764291 chr5:122110994 SNX2 0.38 6.49 0.33 3.08e-10 Mean platelet volume; LIHC cis rs12908161 1.000 rs34900908 chr15:85257599 G/A cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs6570726 0.791 rs9403729 chr6:145907007 C/T cg23711669 chr6:146136114 FBXO30 0.74 12.86 0.57 3.77e-31 Lobe attachment (rater-scored or self-reported); LIHC trans rs4650994 0.525 rs10913574 chr1:178536482 G/C cg05059571 chr16:84539110 KIAA1609 -0.45 -7.51 -0.38 5.16e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7296418 0.961 rs12425850 chr12:123501972 T/C cg05973401 chr12:123451056 ABCB9 0.52 8.25 0.41 3.51e-15 Platelet count; LIHC trans rs13113518 0.812 rs12512737 chr4:56321105 A/T cg15358633 chr12:38710606 ALG10B 0.44 6.29 0.32 9.77e-10 Height; LIHC cis rs7296418 0.961 rs1790121 chr12:123604492 G/A cg05973401 chr12:123451056 ABCB9 0.49 7.52 0.38 4.94e-13 Platelet count; LIHC cis rs7116495 0.609 rs567026 chr11:71769952 C/T cg26138937 chr11:71823887 C11orf51 1.34 10.79 0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC cis rs939574 0.858 rs2891733 chr2:220135208 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.81 8.29 0.41 2.69e-15 Platelet distribution width; LIHC cis rs10792665 0.541 rs2170009 chr11:82641157 A/G cg24227371 chr11:82718527 RAB30 -0.29 -6.82 -0.35 4.09e-11 Obesity-related traits; LIHC cis rs6809651 0.524 rs1356291 chr3:185824644 C/T cg00760338 chr3:185826511 ETV5 0.87 13.17 0.58 2.47e-32 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg24503407 chr1:205819492 PM20D1 0.73 10.37 0.49 4.21e-22 Menarche (age at onset); LIHC cis rs6542838 0.554 rs4311103 chr2:99538362 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -6.56 -0.33 1.93e-10 Fear of minor pain; LIHC trans rs11098499 0.644 rs10050092 chr4:120532085 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.78 0.43 7.85e-17 Corneal astigmatism; LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg20607798 chr8:58055168 NA 0.68 8.45 0.42 8.33e-16 Developmental language disorder (linguistic errors); LIHC cis rs225245 0.817 rs12150359 chr17:34024584 C/T cg05299278 chr17:33885742 SLFN14 0.23 6.12 0.31 2.62e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs7772486 0.754 rs9497419 chr6:146142609 T/C cg05347473 chr6:146136440 FBXO30 0.37 6.14 0.32 2.28e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs227584 0.663 rs2040810 chr17:42243771 C/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.43 -7.72 -0.39 1.28e-13 Bone mineral density (hip);Bone mineral density; LIHC cis rs7447593 0.626 rs3812036 chr5:176813404 C/T cg17509989 chr5:176798049 RGS14 0.74 10.73 0.5 2.5e-23 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs77633900 0.772 rs2948703 chr15:76711751 A/G cg21673338 chr15:77095150 SCAPER -0.52 -5.77 -0.3 1.78e-8 Non-glioblastoma glioma;Glioma; LIHC cis rs367615 0.918 rs17161889 chr5:108855251 A/G cg17395555 chr5:108820864 NA -0.34 -6.97 -0.35 1.63e-11 Colorectal cancer (SNP x SNP interaction); LIHC cis rs35110281 0.748 rs4997353 chr21:45002329 A/C cg04455712 chr21:45112962 RRP1B 0.46 7.94 0.39 2.89e-14 Mean corpuscular volume; LIHC cis rs9902453 0.817 rs9909128 chr17:28161482 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 13.96 0.6 2.37e-35 Coffee consumption (cups per day); LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg02951883 chr7:2050386 MAD1L1 -0.67 -11.11 -0.52 1.05e-24 Bipolar disorder and schizophrenia; LIHC cis rs1557765 0.527 rs2018218 chr11:17390855 A/G cg15432903 chr11:17409602 KCNJ11 0.43 6.57 0.33 1.92e-10 Body mass index;Social communication problems; LIHC cis rs2072499 0.966 rs2244144 chr1:156184598 G/A cg25208724 chr1:156163844 SLC25A44 0.87 13.63 0.59 4.25e-34 Testicular germ cell tumor; LIHC trans rs75804782 0.521 rs72993073 chr2:239412925 G/A cg01134436 chr17:81009848 B3GNTL1 0.78 6.67 0.34 1e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs7937890 0.668 rs12361851 chr11:14267668 C/T cg22961513 chr11:14280813 SPON1 0.42 5.99 0.31 5.26e-9 Mitochondrial DNA levels; LIHC cis rs10504229 0.861 rs57314710 chr8:58196051 T/C cg02290350 chr8:58132656 NA 0.47 9.16 0.44 4.93e-18 Developmental language disorder (linguistic errors); LIHC cis rs68170813 0.599 rs77878465 chr7:106890996 G/A cg02696742 chr7:106810147 HBP1 -0.53 -6.28 -0.32 1.05e-9 Coronary artery disease; LIHC cis rs8060686 0.545 rs9931987 chr16:68256639 G/A cg05110241 chr16:68378359 PRMT7 -0.55 -6.38 -0.33 5.7e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs1997103 0.911 rs6949931 chr7:55391081 T/C cg17469321 chr7:55412551 NA 0.47 7.0 0.35 1.38e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs67478160 0.643 rs12878868 chr14:104233725 G/A cg08213375 chr14:104286397 PPP1R13B 0.66 13.07 0.58 6.09e-32 Schizophrenia; LIHC cis rs10088262 0.629 rs7828192 chr8:124804669 C/T cg20713898 chr8:124780851 FAM91A1 -0.54 -7.38 -0.37 1.22e-12 Pancreatic cancer; LIHC cis rs317689 0.718 rs315130 chr12:69761444 T/C cg20891283 chr12:69753455 YEATS4 0.67 10.53 0.49 1.19e-22 Response to diuretic therapy; LIHC cis rs7044106 0.690 rs10739569 chr9:123361027 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.5 0.49 1.59e-22 Hip circumference adjusted for BMI; LIHC cis rs9790314 0.613 rs1447619 chr3:160616077 A/T cg03342759 chr3:160939853 NMD3 0.56 7.33 0.37 1.63e-12 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09590193 chr11:105947389 KBTBD3;AASDHPPT 0.46 6.32 0.32 8e-10 Pancreatic cancer; LIHC cis rs11785400 1.000 rs7459630 chr8:143738585 A/C cg24634471 chr8:143751801 JRK 0.52 8.35 0.41 1.71e-15 Schizophrenia; LIHC cis rs7131987 0.903 rs11050152 chr12:29404424 G/T cg00204748 chr12:29376779 FAR2 0.43 7.93 0.39 3.05e-14 QT interval; LIHC cis rs754466 0.606 rs10824581 chr10:79599501 A/G cg17075019 chr10:79541650 NA -0.78 -11.74 -0.54 5.61e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg07414643 chr4:187882934 NA 0.23 5.94 0.31 7.01e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1451375 1.000 rs1451374 chr7:50622653 G/A cg14593290 chr7:50529359 DDC 0.4 6.69 0.34 8.93e-11 Malaria; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg27113440 chr11:22214386 ANO5 0.42 6.21 0.32 1.55e-9 Calcium levels; LIHC cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg05527609 chr1:210001259 C1orf107 0.42 6.08 0.31 3.23e-9 Cleft lip with or without cleft palate; LIHC cis rs7772486 0.790 rs2254257 chr6:146203724 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.26 -0.32 1.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg11502198 chr6:26597334 ABT1 -0.59 -9.35 -0.45 1.21e-18 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.935 rs9461270 chr6:26544110 A/G cg11502198 chr6:26597334 ABT1 0.4 5.84 0.3 1.24e-8 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs1534025 chr3:134313304 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.41 5.9 0.3 8.59e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1843834 0.505 rs7585047 chr2:225373897 C/T cg22455342 chr2:225449267 CUL3 0.59 8.53 0.42 4.89e-16 IgE levels in asthmatics (D.p. specific); LIHC cis rs752010 0.714 rs7513753 chr1:42079232 A/G cg06885757 chr1:42089581 HIVEP3 0.3 6.31 0.32 8.45e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs727505 1.000 rs7777947 chr7:124436063 T/G cg23710748 chr7:124431027 NA -0.35 -6.34 -0.32 7.44e-10 Lewy body disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05315670 chr11:64037304 BAD -0.46 -6.5 -0.33 2.87e-10 Hepatitis; LIHC cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg11764359 chr7:65958608 NA -0.59 -6.13 -0.31 2.49e-9 Diabetic kidney disease; LIHC cis rs7617773 0.817 rs9830016 chr3:48282494 A/G cg11946769 chr3:48343235 NME6 0.83 11.13 0.52 8.94e-25 Coronary artery disease; LIHC cis rs1113500 0.966 rs11185249 chr1:108611646 C/A cg06207961 chr1:108661230 NA 0.36 6.95 0.35 1.91e-11 Growth-regulated protein alpha levels; LIHC cis rs155076 0.938 rs9509633 chr13:21844482 G/C cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.34e-30 White matter hyperintensity burden; LIHC cis rs6728642 0.572 rs2872686 chr2:97601024 A/G cg26665480 chr2:98280029 ACTR1B -0.52 -6.49 -0.33 2.97e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs701145 0.586 rs181443 chr3:153959028 G/T cg16511985 chr3:153974050 SGEF 0.42 9.09 0.44 8.41e-18 Coronary artery disease; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg21244745 chr2:242665522 ING5 0.41 6.03 0.31 4.14e-9 Immature fraction of reticulocytes; LIHC cis rs1018836 0.818 rs2285232 chr8:91546162 C/G cg16814680 chr8:91681699 NA -0.57 -9.21 -0.45 3.3e-18 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2576037 0.526 rs538221 chr18:44375111 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.63 9.83 0.47 2.94e-20 Personality dimensions; LIHC cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg18357526 chr6:26021779 HIST1H4A -1.03 -14.71 -0.62 2.79e-38 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg06238570 chr21:40685208 BRWD1 0.47 7.44 0.37 7.99e-13 Cognitive function; LIHC cis rs7197653 0.748 rs61460037 chr16:68336125 A/C cg09835421 chr16:68378352 PRMT7 -0.9 -9.89 -0.47 1.95e-20 Magnesium levels; LIHC cis rs1577917 1.000 rs1995688 chr6:86632319 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC cis rs4969178 0.600 rs4969184 chr17:76393413 G/A cg20026190 chr17:76395443 PGS1 0.4 5.95 0.31 6.78e-9 HDL cholesterol levels; LIHC cis rs9818758 0.607 rs56306491 chr3:49314960 G/A cg07636037 chr3:49044803 WDR6 -0.83 -6.99 -0.35 1.41e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs3540 0.512 rs7176518 chr15:91079637 C/T cg22089800 chr15:90895588 ZNF774 -0.5 -7.26 -0.37 2.6e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs919433 0.889 rs788001 chr2:198213720 C/T cg03934865 chr2:198174659 NA 0.55 8.84 0.43 5.12e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs12479064 0.724 rs3087403 chr2:100058870 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.68 -8.24 -0.41 3.67e-15 Chronic sinus infection; LIHC trans rs1728785 1.000 rs1170431 chr16:68605639 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs3793683 0.858 rs1571145 chr10:134583672 C/G cg06453172 chr10:134556979 INPP5A 0.58 8.18 0.4 5.58e-15 Migraine; LIHC cis rs4820294 1.000 rs739139 chr22:38067011 C/G cg00292662 chr22:38071168 LGALS1 0.64 10.15 0.48 2.4e-21 Fat distribution (HIV); LIHC cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg26119090 chr2:26468346 HADHA;HADHB -1.14 -17.38 -0.68 6.12e-49 Gut microbiome composition (summer); LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs507080 0.961 rs600969 chr11:118545797 C/T cg04173919 chr11:118528438 PHLDB1 0.31 5.72 0.3 2.38e-8 Serum metabolite levels; LIHC cis rs1190552 0.894 rs4906203 chr14:102928991 C/T cg10241871 chr14:102965420 TECPR2 -0.47 -7.39 -0.37 1.12e-12 Blood protein levels; LIHC cis rs10911363 0.592 rs2702182 chr1:183516440 C/T cg09173681 chr1:183549694 NCF2 0.57 10.45 0.49 2.29e-22 Systemic lupus erythematosus; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10463451 chr21:37432625 SETD4 -0.47 -6.9 -0.35 2.56e-11 Cognitive function; LIHC cis rs9399135 0.967 rs1590975 chr6:135352088 C/T cg22676075 chr6:135203613 NA 0.38 6.22 0.32 1.41e-9 Red blood cell count; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.43 -6.05 -0.31 3.77e-9 Longevity; LIHC cis rs965469 0.708 rs80050989 chr20:3297881 A/G cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19729279 chr5:133861951 PHF15 0.42 6.21 0.32 1.52e-9 Pancreatic cancer; LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs72781680 0.716 rs78332127 chr2:24150163 C/G cg08917208 chr2:24149416 ATAD2B 0.64 6.4 0.33 5.15e-10 Lymphocyte counts; LIHC cis rs12048904 0.619 rs10783153 chr1:101328230 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 11.34 0.52 1.57e-25 Multiple sclerosis; LIHC cis rs2749592 1.000 rs2749592 chr10:38258842 A/C cg25427524 chr10:38739819 LOC399744 -0.54 -9.33 -0.45 1.33e-18 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs17401966 0.931 rs12131441 chr1:10428952 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.73 -0.34 7.04e-11 Hepatocellular carcinoma; LIHC cis rs10818894 0.611 rs10117455 chr9:126692599 G/T cg16191174 chr9:126692580 DENND1A 0.62 7.08 0.36 8.11e-12 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); LIHC cis rs28735056 0.572 rs4799100 chr18:77640207 A/G cg20368463 chr18:77673604 PQLC1 -0.49 -8.31 -0.41 2.36e-15 Schizophrenia; LIHC cis rs7119038 0.865 rs11217044 chr11:118696022 T/C cg19308663 chr11:118741387 NA 0.39 5.95 0.31 6.6e-9 Sjögren's syndrome; LIHC cis rs3892630 0.878 rs6510277 chr19:33183669 C/A cg22980127 chr19:33182716 NUDT19 1.04 12.47 0.56 1.16e-29 Red blood cell traits; LIHC cis rs3020736 0.500 rs6002604 chr22:42493081 A/T cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg03264133 chr6:25882463 NA -0.49 -6.01 -0.31 4.69e-9 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10963192 chr14:100751514 NA 0.45 6.11 0.31 2.64e-9 Lung function (FEV1/FVC); LIHC cis rs4668356 0.687 rs7563109 chr2:172047280 A/C cg13882835 chr2:172017928 TLK1 0.44 6.03 0.31 4.3e-9 Cognitive performance; LIHC cis rs6089584 1.000 rs6089587 chr20:60564829 C/T cg06108461 chr20:60628389 TAF4 -0.88 -13.71 -0.6 2.16e-34 Body mass index; LIHC cis rs6088580 0.634 rs6142153 chr20:32968747 C/G cg08999081 chr20:33150536 PIGU -0.66 -13.16 -0.58 2.69e-32 Glomerular filtration rate (creatinine); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09430954 chr19:46236890 NA 0.5 6.97 0.35 1.66e-11 Longevity; LIHC cis rs7927592 0.731 rs11228275 chr11:68303980 G/A cg01657329 chr11:68192670 LRP5 0.52 7.7 0.38 1.52e-13 Total body bone mineral density; LIHC trans rs7980799 0.716 rs10161311 chr12:33623204 G/A cg26384229 chr12:38710491 ALG10B -0.45 -6.1 -0.31 2.86e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs4888262 0.526 rs8062959 chr16:74627628 T/C cg01733217 chr16:74700730 RFWD3 0.83 16.18 0.66 3.82e-44 Testicular germ cell tumor; LIHC cis rs12188164 0.543 rs2434695 chr5:464177 C/G cg24955955 chr5:415729 AHRR 0.31 6.35 0.32 6.83e-10 Cystic fibrosis severity; LIHC cis rs2705520 0.546 rs2705535 chr3:112208927 C/T cg09473763 chr3:112282684 SLC35A5 -0.86 -8.8 -0.43 7.11e-17 Asthma (childhood onset); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg21475434 chr5:93447410 FAM172A 0.42 6.66 0.34 1.12e-10 Calcium levels; LIHC cis rs13392177 0.684 rs62185965 chr2:219073779 T/C cg00012203 chr2:219082015 ARPC2 -0.75 -11.24 -0.52 3.6e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs7818688 0.697 rs17665714 chr8:95982542 T/C cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2302190 0.882 rs12939703 chr17:56611090 G/C cg12560992 chr17:57184187 TRIM37 0.69 8.88 0.43 3.9e-17 Vitamin D levels; LIHC trans rs16962242 0.744 rs9300813 chr13:104048657 G/A cg12071008 chr17:76457640 DNAH17 0.46 6.09 0.31 3.01e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2832191 0.791 rs2065270 chr21:30485420 T/C cg24692254 chr21:30365293 RNF160 -0.68 -12.47 -0.56 1.13e-29 Dental caries; LIHC cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg03517284 chr6:25882590 NA -0.46 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg18230493 chr5:56204884 C5orf35 -0.45 -6.0 -0.31 4.89e-9 Type 2 diabetes; LIHC cis rs6429082 0.715 rs9793740 chr1:235595590 T/C cg26050004 chr1:235667680 B3GALNT2 -0.47 -7.24 -0.36 2.95e-12 Adiposity; LIHC cis rs1008375 0.932 rs6449317 chr4:17631253 T/C cg02297831 chr4:17616191 MED28 0.45 6.27 0.32 1.1e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1062177 1.000 rs6890099 chr5:151151962 A/G cg00977110 chr5:151150581 G3BP1 0.56 7.11 0.36 6.8e-12 Preschool internalizing problems; LIHC cis rs986417 0.892 rs8012339 chr14:60797545 T/G cg27398547 chr14:60952738 C14orf39 -0.74 -7.5 -0.38 5.71e-13 Gut microbiota (bacterial taxa); LIHC cis rs17685 0.753 rs6464999 chr7:75787315 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs6461503 0.644 rs916789 chr7:20572530 A/C cg17324776 chr17:41116197 AARSD1 0.41 6.18 0.32 1.79e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2839186 0.681 rs13047198 chr21:47701835 T/C cg12379764 chr21:47803548 PCNT -0.58 -8.08 -0.4 1.12e-14 Testicular germ cell tumor; LIHC cis rs2033908 0.620 rs1440272 chr11:12852309 G/A cg25843174 chr11:12811716 TEAD1 -0.31 -7.11 -0.36 6.99e-12 Sitting height ratio; LIHC cis rs950776 0.616 rs495090 chr15:78870003 A/G cg06917634 chr15:78832804 PSMA4 -0.59 -7.98 -0.4 2.3e-14 Sudden cardiac arrest; LIHC cis rs4969178 0.930 rs12601079 chr17:76400329 G/A cg20026190 chr17:76395443 PGS1 0.45 7.12 0.36 6.51e-12 HDL cholesterol levels; LIHC cis rs288342 0.933 rs288346 chr2:183667120 G/A cg02625481 chr2:183667124 NA -0.28 -5.84 -0.3 1.18e-8 Recurrent major depressive disorder; LIHC cis rs35306767 0.953 rs11253509 chr10:964306 C/T cg26597838 chr10:835615 NA 0.97 11.78 0.54 4.14e-27 Eosinophil percentage of granulocytes; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg06873352 chr17:61820015 STRADA 0.72 12.72 0.57 1.29e-30 Prudent dietary pattern; LIHC trans rs9858542 0.953 rs9837341 chr3:49664767 A/G cg21659725 chr3:3221576 CRBN -0.59 -6.46 -0.33 3.57e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9457247 0.534 rs9347170 chr6:167405187 C/T cg12798992 chr6:167411361 FGFR1OP -0.49 -7.96 -0.4 2.48e-14 Crohn's disease; LIHC trans rs561341 0.943 rs508566 chr17:30289861 G/C cg20587970 chr11:113659929 NA -1.35 -10.99 -0.51 2.87e-24 Hip circumference adjusted for BMI; LIHC cis rs898097 0.841 rs2271918 chr17:80861206 A/G cg15664640 chr17:80829946 TBCD -0.75 -12.53 -0.56 6.55e-30 Breast cancer; LIHC cis rs7833790 1.000 rs7833384 chr8:82730915 T/C cg02079420 chr8:82753780 SNX16 0.34 5.83 0.3 1.28e-8 Diastolic blood pressure; LIHC cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg01788221 chr16:89496183 ANKRD11 -0.38 -5.88 -0.3 9.8e-9 Multiple myeloma (IgH translocation); LIHC cis rs9534288 0.956 rs2094244 chr13:46605803 T/C cg15192986 chr13:46630673 CPB2 -0.57 -8.69 -0.43 1.56e-16 Blood protein levels; LIHC cis rs6089584 0.888 rs6089624 chr20:60619907 C/G cg06108461 chr20:60628389 TAF4 -1.0 -17.78 -0.69 1.57e-50 Body mass index; LIHC cis rs1816752 0.633 rs9578729 chr13:24999244 T/A cg22771759 chr13:24902376 NA 0.32 6.57 0.33 1.9e-10 Obesity-related traits; LIHC cis rs910316 0.763 rs13712 chr14:75483812 T/C cg08847533 chr14:75593920 NEK9 0.88 18.48 0.71 2.22e-53 Height; LIHC trans rs804280 0.509 rs12719915 chr8:11786255 A/G cg23218760 chr8:16884364 EFHA2 0.48 6.27 0.32 1.11e-9 Myopia (pathological); LIHC cis rs7937682 0.824 rs11213962 chr11:111506027 G/A cg09085632 chr11:111637200 PPP2R1B -1.03 -12.34 -0.56 3.41e-29 Primary sclerosing cholangitis; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg18110333 chr6:292329 DUSP22 -0.55 -7.35 -0.37 1.45e-12 Menopause (age at onset); LIHC cis rs1144333 0.655 rs76794487 chr1:76384055 G/A cg10523679 chr1:76189770 ACADM 0.46 6.14 0.31 2.34e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2455601 1.000 rs12223690 chr11:8901824 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.5 -6.51 -0.33 2.63e-10 Schizophrenia; LIHC cis rs875971 0.660 rs10281080 chr7:66042441 T/C cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC cis rs4803455 0.565 rs11670143 chr19:41864971 A/G cg09537434 chr19:41945824 ATP5SL -0.72 -10.85 -0.51 9.17e-24 Migraine;Coronary artery disease; LIHC cis rs12594515 1.000 rs8038058 chr15:45990272 C/T cg06207120 chr15:45996521 NA 0.35 6.82 0.35 4.17e-11 Waist circumference;Weight; LIHC cis rs2066819 1.000 rs58852079 chr12:56706922 A/C cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs35110281 0.641 rs4818858 chr21:45083097 C/T cg04455712 chr21:45112962 RRP1B -0.51 -8.63 -0.42 2.28e-16 Mean corpuscular volume; LIHC cis rs9443645 0.901 rs9352667 chr6:79572296 A/G cg05283184 chr6:79620031 NA 0.34 5.83 0.3 1.26e-8 Intelligence (multi-trait analysis); LIHC cis rs7677751 0.848 rs7673625 chr4:55088586 C/T cg17187183 chr4:55093834 PDGFRA 0.67 8.4 0.41 1.2e-15 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10668512 chr15:42565522 GANC;TMEM87A 0.52 7.43 0.37 8.59e-13 Pancreatic cancer; LIHC cis rs4660306 0.744 rs11583290 chr1:45926363 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.62 6.81 0.35 4.27e-11 Homocysteine levels; LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.73 -0.3 2.22e-8 Total body bone mineral density; LIHC cis rs3790645 1.000 rs657227 chr1:26892104 T/A cg23229016 chr1:26872525 RPS6KA1 0.23 5.75 0.3 1.95e-8 Glucose homeostasis traits; LIHC cis rs311392 0.554 rs2013501 chr8:55104313 A/G cg11783602 chr8:55087084 NA -0.3 -6.11 -0.31 2.73e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs10876993 0.928 rs2640637 chr12:58077586 G/A cg15848620 chr12:58087721 OS9 -0.59 -8.1 -0.4 9.68e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs62079673 0.527 rs9788998 chr17:80605644 A/G cg27136344 chr17:80606911 WDR45L 0.62 10.14 0.48 2.69e-21 Breast cancer; LIHC cis rs2842992 0.724 rs2273823 chr6:160211485 T/C cg11366901 chr6:160182831 ACAT2 0.86 14.38 0.61 5.22e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs9649213 0.533 rs1541409 chr7:98027580 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.56 -9.78 -0.47 4.53e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg02782426 chr3:40428986 ENTPD3 -0.34 -6.29 -0.32 9.67e-10 Renal cell carcinoma; LIHC cis rs1419980 0.730 rs11559767 chr12:7748555 C/T cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg08859206 chr1:53392774 SCP2 0.37 6.03 0.31 4.21e-9 Monocyte count; LIHC cis rs9916302 0.904 rs12450559 chr17:37694709 G/A cg00129232 chr17:37814104 STARD3 -0.42 -6.72 -0.34 7.42e-11 Glomerular filtration rate (creatinine); LIHC cis rs7769051 1.000 rs9493443 chr6:133121349 C/T cg07930552 chr6:133119739 C6orf192 0.66 6.52 0.33 2.49e-10 Type 2 diabetes nephropathy; LIHC cis rs6964587 0.507 rs12539439 chr7:91917365 A/C cg17063962 chr7:91808500 NA 0.96 15.91 0.65 4.73e-43 Breast cancer; LIHC cis rs79057730 0.599 rs6951032 chr7:794092 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.92 10.19 0.48 1.83e-21 Initial pursuit acceleration; LIHC trans rs637571 0.584 rs659824 chr11:65636509 A/G cg17712092 chr4:129076599 LARP1B -0.67 -9.94 -0.47 1.24e-20 Eosinophil percentage of white cells; LIHC cis rs4975709 0.544 rs4975748 chr5:1866025 G/A cg15595755 chr5:1867978 NA 0.42 8.3 0.41 2.52e-15 Cardiovascular disease risk factors; LIHC cis rs7107174 0.901 rs2510053 chr11:77959435 T/C cg02023728 chr11:77925099 USP35 0.44 8.58 0.42 3.48e-16 Testicular germ cell tumor; LIHC cis rs801193 0.636 rs2659895 chr7:66196471 C/A cg11764359 chr7:65958608 NA 0.83 14.75 0.62 1.92e-38 Aortic root size; LIHC trans rs7618501 1.000 rs695238 chr3:49869158 A/C cg21582582 chr3:182698605 DCUN1D1 0.54 7.13 0.36 6.18e-12 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.529 rs1780125 chr10:38531376 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.43 -6.35 -0.32 6.86e-10 Extrinsic epigenetic age acceleration; LIHC trans rs2832191 0.692 rs2245517 chr21:30357968 C/T cg14791747 chr16:20752902 THUMPD1 -0.49 -6.86 -0.35 3.2e-11 Dental caries; LIHC cis rs7224685 0.906 rs2304586 chr17:4098998 A/G cg09597638 chr17:3907349 NA 0.55 7.55 0.38 4e-13 Type 2 diabetes; LIHC cis rs986417 1.000 rs1956557 chr14:60972569 G/A cg27398547 chr14:60952738 C14orf39 0.77 8.73 0.43 1.16e-16 Gut microbiota (bacterial taxa); LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg22528358 chr1:107598549 PRMT6 -0.69 -11.48 -0.53 4.96e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1008375 0.932 rs13127157 chr4:17618049 A/G cg02297831 chr4:17616191 MED28 -0.44 -6.05 -0.31 3.8e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2948294 0.588 rs4840913 chr8:8116906 A/C cg06636001 chr8:8085503 FLJ10661 0.44 7.07 0.36 8.52e-12 Red cell distribution width; LIHC trans rs9788333 0.695 rs12871086 chr13:21890224 A/T cg02569823 chr6:5851330 NA 0.39 6.27 0.32 1.11e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs881375 0.967 rs758959 chr9:123676699 C/T cg14580859 chr9:123691850 NA 0.37 6.55 0.33 2.11e-10 Rheumatoid arthritis; LIHC cis rs1941023 0.584 rs2197236 chr11:60168859 T/C cg08716584 chr11:60157161 MS4A7 -0.36 -8.25 -0.41 3.45e-15 Congenital heart disease (maternal effect); LIHC cis rs854765 0.647 rs7212447 chr17:17987067 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.34 6.32 0.32 8.09e-10 Total body bone mineral density; LIHC cis rs3106136 0.934 rs34396188 chr4:95191292 A/C cg11021082 chr4:95130006 SMARCAD1 -0.34 -6.36 -0.33 6.32e-10 Capecitabine sensitivity; LIHC cis rs4665809 1.000 rs1371553 chr2:26262948 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.68 -0.42 1.68e-16 Gut microbiome composition (summer); LIHC cis rs2502731 1.000 rs2502731 chr9:130976557 A/G cg09976142 chr9:130955436 CIZ1 -0.5 -7.5 -0.38 5.4e-13 Attention deficit hyperactivity disorder; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg27400282 chr2:201446673 SGOL2 -0.28 -6.63 -0.34 1.28e-10 Calcium levels; LIHC cis rs6500602 0.727 rs55939215 chr16:4541390 C/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 5.86 0.3 1.08e-8 Schizophrenia; LIHC cis rs7258465 1.000 rs7252848 chr19:18612351 C/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.44 -0.37 8.37e-13 Breast cancer; LIHC cis rs34330 0.562 rs11055025 chr12:12866619 A/T cg09462578 chr12:12878428 APOLD1 -0.78 -10.56 -0.5 9.39e-23 Systemic lupus erythematosus; LIHC cis rs4824093 0.610 rs73443974 chr22:50314316 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -5.73 -0.3 2.16e-8 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs782590 0.818 rs2627782 chr2:55825352 A/G cg03859395 chr2:55845619 SMEK2 0.72 11.75 0.54 5.37e-27 Metabolic syndrome; LIHC trans rs9929218 0.859 rs9936682 chr16:68748223 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.64 -9.52 -0.46 3.35e-19 Colorectal cancer; LIHC cis rs12048904 0.505 rs11166511 chr1:101240686 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.58 -8.77 -0.43 8.32e-17 Multiple sclerosis; LIHC cis rs17152411 1.000 rs12573033 chr10:126607803 T/G cg07906193 chr10:126599966 NA 0.46 7.17 0.36 4.78e-12 Height; LIHC cis rs8067354 0.574 rs1292050 chr17:57965169 T/C cg02344993 chr17:57696989 CLTC 0.65 10.2 0.48 1.68e-21 Hemoglobin concentration; LIHC cis rs860295 0.665 rs11264367 chr1:155337338 T/C cg02153340 chr1:155202674 NA -0.33 -5.87 -0.3 1.01e-8 Body mass index; LIHC cis rs9948 0.786 rs62156234 chr2:97436292 C/G cg01990225 chr2:97406019 LMAN2L -0.72 -6.27 -0.32 1.12e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs4803468 0.967 rs892044 chr19:41903671 A/G cg14132834 chr19:41945861 ATP5SL -0.44 -6.61 -0.34 1.48e-10 Height; LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg11070056 chr1:107600091 PRMT6 0.7 12.14 0.55 1.9e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs68170813 0.559 rs12537730 chr7:106844281 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs2842992 0.872 rs2758315 chr6:160158640 T/C cg19482086 chr6:160211437 TCP1;MRPL18 0.71 12.63 0.56 2.94e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs1550582 1.000 rs7822348 chr8:135542483 C/G cg17885191 chr8:135476712 NA 0.35 5.87 0.3 1.01e-8 Educational attainment; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04127825 chr1:167503222 NA 0.46 7.42 0.37 9.47e-13 Cognitive function; LIHC cis rs2439831 1.000 rs689781 chr15:43792097 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.64 9.01 0.44 1.47e-17 Lung cancer in ever smokers; LIHC cis rs507080 0.961 rs656505 chr11:118549954 G/A cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC cis rs61990749 0.597 rs8016416 chr14:78213100 T/A cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.16 0.48 2.37e-21 Fibroblast growth factor basic levels; LIHC cis rs9534288 0.763 rs9534273 chr13:46566988 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 11.79 0.54 3.8e-27 Height; LIHC cis rs7927592 0.731 rs11228275 chr11:68303980 G/A cg16797656 chr11:68205561 LRP5 -0.5 -8.82 -0.43 6.15e-17 Total body bone mineral density; LIHC cis rs2115630 0.967 rs7171167 chr15:85239123 A/T cg12501888 chr15:85177176 SCAND2 -0.54 -8.42 -0.41 1.05e-15 P wave terminal force; LIHC cis rs2463822 0.844 rs72923263 chr11:62161170 C/G cg06239285 chr11:62104954 ASRGL1 -0.92 -6.29 -0.32 9.75e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2075371 0.611 rs12707154 chr7:134015832 C/T cg20476274 chr7:133979776 SLC35B4 0.5 6.64 0.34 1.23e-10 Mean platelet volume; LIHC cis rs6061231 0.793 rs2427320 chr20:60976723 A/G cg24112000 chr20:60950667 NA -0.62 -8.2 -0.41 5.05e-15 Colorectal cancer; LIHC cis rs2243480 1.000 rs1796220 chr7:66062100 C/T cg12463550 chr7:65579703 CRCP 0.66 6.86 0.35 3.28e-11 Diabetic kidney disease; LIHC cis rs2834256 0.884 rs11088260 chr21:35081807 G/A cg14850771 chr21:34775459 IFNGR2 0.41 6.36 0.33 6.29e-10 Red cell distribution width; LIHC cis rs4820294 1.000 rs4820294 chr22:38071043 G/A cg10587741 chr22:38071170 LGALS1 0.74 12.88 0.57 3.09e-31 Fat distribution (HIV); LIHC cis rs9457247 1.000 rs2149091 chr6:167372786 C/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.94 -0.47 1.26e-20 Crohn's disease; LIHC cis rs6750795 0.765 rs6742387 chr2:232354832 G/T cg19187155 chr2:232395269 NMUR1 0.58 8.78 0.43 8.25e-17 Height; LIHC cis rs798554 0.679 rs2527681 chr7:2892384 A/T cg19346786 chr7:2764209 NA -0.36 -5.87 -0.3 1.04e-8 Height; LIHC trans rs561341 0.941 rs8066156 chr17:30361629 A/G cg20587970 chr11:113659929 NA -1.0 -9.69 -0.46 8.84e-20 Hip circumference adjusted for BMI; LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg14709524 chr16:89940631 TCF25 -0.51 -6.58 -0.34 1.74e-10 Skin colour saturation; LIHC cis rs9318086 0.663 rs2312295 chr13:24457744 A/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.57 11.17 0.52 6.49e-25 Myopia (pathological); LIHC cis rs35110281 0.666 rs2236665 chr21:45108987 C/A cg21573476 chr21:45109991 RRP1B -0.61 -11.7 -0.53 8.04e-27 Mean corpuscular volume; LIHC cis rs8114671 0.539 rs2064453 chr20:33460810 T/C cg07148914 chr20:33460835 GGT7 0.64 9.6 0.46 1.79e-19 Height; LIHC cis rs1538970 0.847 rs1771550 chr1:45883565 C/T cg05343316 chr1:45956843 TESK2 -0.52 -7.58 -0.38 3.2e-13 Platelet count; LIHC cis rs6430585 0.528 rs79826902 chr2:136670419 G/A cg15123519 chr2:136567270 LCT -0.36 -5.77 -0.3 1.76e-8 Corneal structure; LIHC cis rs2295359 0.824 rs12060309 chr1:67604219 T/C cg12940439 chr1:67600707 NA 0.38 6.55 0.33 2.07e-10 Psoriasis; LIHC cis rs4555082 0.874 rs3000075 chr14:105713219 C/T cg10792982 chr14:105748885 BRF1 -0.47 -6.66 -0.34 1.1e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs28735056 0.584 rs35614280 chr18:77636679 C/G cg20368463 chr18:77673604 PQLC1 0.55 7.81 0.39 7.11e-14 Schizophrenia; LIHC cis rs9457247 0.902 rs366938 chr6:167403538 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.02 -0.51 2.23e-24 Crohn's disease; LIHC cis rs6951245 0.529 rs10262070 chr7:1141738 C/T cg04025307 chr7:1156635 C7orf50 0.64 6.4 0.33 5.1e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2549003 1.000 rs6873426 chr5:131818631 G/T cg02551604 chr5:131831745 NA -0.44 -6.54 -0.33 2.24e-10 Asthma (sex interaction); LIHC cis rs801193 0.591 rs721717 chr7:66130292 G/T cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs11212260 0.655 rs117631524 chr11:107336026 T/C cg25435332 chr11:107328525 CWF19L2 0.84 8.24 0.41 3.8e-15 IgG glycosylation; LIHC cis rs8014204 0.836 rs888413 chr14:75267396 C/T cg08847533 chr14:75593920 NEK9 0.34 5.72 0.3 2.29e-8 Caffeine consumption; LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.18 0.61 3.31e-36 Prudent dietary pattern; LIHC cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.81 8.07 0.4 1.18e-14 Platelet count; LIHC cis rs950776 0.518 rs12910100 chr15:78822667 C/T cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs9457247 0.555 rs2247325 chr6:167369992 A/G cg07741184 chr6:167504864 NA -0.27 -6.05 -0.31 3.83e-9 Crohn's disease; LIHC cis rs7772486 0.875 rs9403770 chr6:146423334 C/T cg13319975 chr6:146136371 FBXO30 -0.38 -6.11 -0.31 2.78e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs8073060 0.586 rs225286 chr17:33930458 G/A cg19694781 chr19:47549865 TMEM160 -1.25 -12.76 -0.57 9.07e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2075371 0.897 rs1643102 chr7:133999983 T/A cg20476274 chr7:133979776 SLC35B4 0.74 12.16 0.55 1.65e-28 Mean platelet volume; LIHC cis rs7086627 0.515 rs6585994 chr10:82191643 A/G cg00277334 chr10:82204260 NA -0.62 -10.55 -0.5 1e-22 Post bronchodilator FEV1; LIHC cis rs507080 0.845 rs613377 chr11:118556084 C/T cg04173919 chr11:118528438 PHLDB1 0.35 6.58 0.34 1.8e-10 Serum metabolite levels; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg06873352 chr17:61820015 STRADA 0.73 12.64 0.56 2.61e-30 Prudent dietary pattern; LIHC cis rs8078723 0.714 rs8070444 chr17:38151960 A/G cg17467752 chr17:38218738 THRA -0.61 -10.3 -0.49 7.33e-22 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2580764 0.565 rs2919129 chr2:55216545 G/T cg09592903 chr2:55203963 RTN4 0.69 12.97 0.57 1.51e-31 Mean platelet volume; LIHC cis rs11212260 0.655 rs11212209 chr11:107278735 T/C cg25435332 chr11:107328525 CWF19L2 0.81 8.77 0.43 8.76e-17 IgG glycosylation; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg06873352 chr17:61820015 STRADA 0.74 13.1 0.58 4.69e-32 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg23758822 chr17:41437982 NA 0.94 17.84 0.69 8.48e-51 Menopause (age at onset); LIHC cis rs6762 0.719 rs4895 chr11:840477 A/G cg16425592 chr11:842748 TSPAN4;POLR2L -0.81 -9.72 -0.47 6.83e-20 Mean platelet volume; LIHC cis rs9393777 0.623 rs9358946 chr6:26478927 G/A cg12826209 chr6:26865740 GUSBL1 0.66 6.97 0.35 1.65e-11 Intelligence (multi-trait analysis); LIHC trans rs2726453 0.562 rs2713834 chr4:106310520 G/T cg24541279 chr10:71993373 PPA1 -0.48 -6.25 -0.32 1.23e-9 Intelligence (multi-trait analysis); LIHC cis rs10792665 0.512 rs4551795 chr11:82589970 A/G cg24227371 chr11:82718527 RAB30 -0.28 -6.58 -0.34 1.78e-10 Obesity-related traits; LIHC cis rs2115536 0.730 rs4238512 chr15:80183898 A/C cg11839771 chr15:80205821 ST20 0.28 5.77 0.3 1.77e-8 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs35110281 0.774 rs1378080 chr21:45011315 T/A cg01579765 chr21:45077557 HSF2BP -0.36 -6.9 -0.35 2.47e-11 Mean corpuscular volume; LIHC cis rs17539620 0.624 rs62432743 chr6:154836214 T/G cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.7 -11.32 -0.52 1.98e-25 Height; LIHC cis rs2836974 0.568 rs11910906 chr21:40685662 T/C cg17971929 chr21:40555470 PSMG1 -0.45 -6.8 -0.35 4.72e-11 Cognitive function; LIHC cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.77e-9 Bipolar disorder; LIHC cis rs732505 1.000 rs4807790 chr19:5584614 A/G cg26242866 chr19:5711310 LONP1 0.83 6.22 0.32 1.44e-9 vWF and FVIII levels; LIHC cis rs875971 0.540 rs35510581 chr7:65578777 G/A cg18876405 chr7:65276391 NA -0.5 -8.45 -0.42 8.23e-16 Aortic root size; LIHC cis rs35110281 0.805 rs2838317 chr21:44991791 A/C cg01579765 chr21:45077557 HSF2BP -0.35 -6.64 -0.34 1.25e-10 Mean corpuscular volume; LIHC cis rs17106184 1.000 rs113870552 chr1:50923454 T/C cg07174182 chr1:51127561 FAF1 -0.56 -6.01 -0.31 4.63e-9 Type 2 diabetes; LIHC cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg10560079 chr2:191398806 TMEM194B 0.52 8.19 0.41 5.09e-15 Pulse pressure; LIHC cis rs6088590 0.965 rs6058108 chr20:33288655 A/G cg24642439 chr20:33292090 TP53INP2 0.76 10.9 0.51 6.3e-24 Coronary artery disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25377475 chr1:236030556 LYST -0.42 -6.27 -0.32 1.1e-9 Systolic blood pressure; LIHC cis rs9534288 0.699 rs9567621 chr13:46665814 A/G cg15192986 chr13:46630673 CPB2 -0.41 -5.71 -0.3 2.46e-8 Blood protein levels; LIHC cis rs60871478 1.000 rs67721251 chr7:825114 T/C cg04727924 chr7:799746 HEATR2 -0.59 -8.8 -0.43 7.07e-17 Cerebrospinal P-tau181p levels; LIHC cis rs3204270 0.639 rs62080199 chr17:79627906 T/G cg18367735 chr17:79674897 NA 0.73 8.21 0.41 4.64e-15 Dental caries; LIHC cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.89 8.56 0.42 3.93e-16 Platelet count; LIHC cis rs11190604 1.000 rs11190552 chr10:102206607 G/A cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9486715 0.867 rs12207471 chr6:96963782 A/G cg06623918 chr6:96969491 KIAA0776 0.86 15.04 0.63 1.41e-39 Headache; LIHC cis rs4474465 0.688 rs7942527 chr11:78280322 A/G cg02023728 chr11:77925099 USP35 -0.33 -5.96 -0.31 6.23e-9 Alzheimer's disease (survival time); LIHC cis rs9814567 1.000 rs4535272 chr3:134299916 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.15 0.32 2.13e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs17685 0.743 rs10277259 chr7:75802674 A/C cg16684958 chr7:75615977 POR 0.52 8.57 0.42 3.5e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7578199 0.850 rs71430328 chr2:242279980 T/G cg19372975 chr2:242212901 HDLBP -0.62 -5.87 -0.3 1.02e-8 Chronic lymphocytic leukemia; LIHC cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg02187348 chr16:89574699 SPG7 0.64 10.14 0.48 2.66e-21 Multiple myeloma (IgH translocation); LIHC cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg25072359 chr17:41440525 NA 0.39 6.28 0.32 1.01e-9 Menopause (age at onset); LIHC cis rs4474465 1.000 rs10899518 chr11:78180508 A/C cg27205649 chr11:78285834 NARS2 -0.38 -5.84 -0.3 1.22e-8 Alzheimer's disease (survival time); LIHC cis rs9303401 0.614 rs2333409 chr17:57139134 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.91 0.54 1.32e-27 Cognitive test performance; LIHC cis rs9733 0.596 rs34600506 chr1:150687808 C/G cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg10295955 chr4:187884368 NA -0.97 -22.75 -0.78 1.95e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs644799 1.000 rs494829 chr11:95571750 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.49 0.67 2.29e-45 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.46 0.46 5.31e-19 Bipolar disorder; LIHC cis rs807029 0.577 rs11190786 chr10:102757442 A/G cg17130504 chr10:102756923 LZTS2 0.55 7.55 0.38 4.02e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg00656387 chr3:40428638 ENTPD3 0.42 6.84 0.35 3.64e-11 Renal cell carcinoma; LIHC cis rs1336900 0.544 rs10888386 chr1:150611957 A/G cg18016565 chr1:150552671 MCL1 -0.62 -12.41 -0.56 1.91e-29 Blood protein levels; LIHC cis rs2153535 0.580 rs9328486 chr6:8528008 T/C cg23788917 chr6:8435910 SLC35B3 0.64 9.08 0.44 8.77e-18 Motion sickness; LIHC cis rs4819052 0.819 rs8134084 chr21:46693295 G/A cg22633049 chr21:46681294 NA -0.38 -6.41 -0.33 4.75e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6089584 0.927 rs3787427 chr20:60579789 T/C cg23262073 chr20:60523788 NA -0.28 -5.73 -0.3 2.16e-8 Body mass index; LIHC trans rs6598955 0.627 rs12143920 chr1:26575834 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg10500953 chr16:346518 AXIN1 0.48 6.27 0.32 1.11e-9 Hepatitis; LIHC cis rs882732 1.000 rs10139277 chr14:95035060 C/T cg14866387 chr14:95027382 SERPINA4 -0.44 -6.34 -0.32 7.42e-10 Blood protein levels; LIHC cis rs832540 0.669 rs832539 chr5:56199386 A/C cg24531977 chr5:56204891 C5orf35 -0.46 -6.71 -0.34 8.05e-11 Coronary artery disease; LIHC cis rs6964587 0.934 rs4512319 chr7:91733829 G/A cg17063962 chr7:91808500 NA 0.96 15.47 0.64 2.62e-41 Breast cancer; LIHC cis rs9513627 1.000 rs73556178 chr13:100121947 T/C cg25919922 chr13:100150906 NA -0.8 -7.07 -0.36 8.77e-12 Obesity-related traits; LIHC cis rs7903847 0.642 rs2275581 chr10:99126249 G/A cg06359132 chr10:99160096 RRP12 -0.39 -5.72 -0.3 2.38e-8 Granulocyte percentage of myeloid white cells; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg10025462 chr17:27046956 SNORD42B;RPL23A -0.54 -6.87 -0.35 2.96e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs62103177 0.733 rs62096747 chr18:77619568 A/G cg05926928 chr17:57297772 GDPD1 1.12 11.56 0.53 2.54e-26 Opioid sensitivity; LIHC cis rs7589728 1.000 rs75181745 chr2:88520408 C/T cg07952391 chr2:88470173 THNSL2 0.65 5.82 0.3 1.32e-8 Plasma clusterin levels; LIHC cis rs35110281 0.744 rs162373 chr21:44927107 C/A cg04455712 chr21:45112962 RRP1B -0.44 -7.39 -0.37 1.15e-12 Mean corpuscular volume; LIHC cis rs2991971 0.933 rs666720 chr1:46020795 T/C cg24296786 chr1:45957014 TESK2 0.5 7.08 0.36 8.12e-12 High light scatter reticulocyte count; LIHC cis rs992157 0.798 rs2382819 chr2:219155909 G/T cg00012203 chr2:219082015 ARPC2 -0.83 -13.16 -0.58 2.79e-32 Colorectal cancer; LIHC cis rs61677309 1.000 rs1599809 chr11:118179200 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.37 0.33 5.97e-10 Lung cancer in ever smokers; LIHC cis rs4820539 1.000 rs5759595 chr22:23471624 G/A cg14186256 chr22:23484241 RTDR1 0.98 21.52 0.76 1.48e-65 Bone mineral density; LIHC cis rs2180341 1.000 rs7776136 chr6:127638348 A/T cg24812749 chr6:127587940 RNF146 1.01 15.08 0.63 9.4e-40 Breast cancer; LIHC cis rs9905704 0.647 rs11650809 chr17:56972741 A/G cg12560992 chr17:57184187 TRIM37 0.68 9.93 0.47 1.36e-20 Testicular germ cell tumor; LIHC cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg06238570 chr21:40685208 BRWD1 -0.47 -7.66 -0.38 1.96e-13 Cognitive function; LIHC cis rs3020736 0.500 rs6002603 chr22:42492362 C/G cg04733989 chr22:42467013 NAGA -0.66 -9.37 -0.45 1.01e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs4906332 0.933 rs34606394 chr14:103915636 G/A cg26031613 chr14:104095156 KLC1 -0.4 -5.73 -0.3 2.23e-8 Coronary artery disease; LIHC cis rs6430585 0.793 rs11684545 chr2:136539122 G/T cg17750252 chr2:136567154 LCT 0.36 6.28 0.32 1.01e-9 Corneal structure; LIHC cis rs10504073 0.647 rs4493918 chr8:50015937 C/G cg00325661 chr8:49890786 NA 0.32 7.27 0.37 2.45e-12 Blood metabolite ratios; LIHC cis rs3862260 0.509 rs3795662 chr1:120165135 G/T cg16322792 chr1:120165303 ZNF697 0.52 9.46 0.46 5.04e-19 Systemic lupus erythematosus; LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg02782426 chr3:40428986 ENTPD3 0.35 6.48 0.33 3.17e-10 Renal cell carcinoma; LIHC cis rs56104184 0.723 rs1058483 chr19:49407660 G/A cg15549821 chr19:49342101 PLEKHA4 -0.65 -6.1 -0.31 2.87e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs919433 0.519 rs700658 chr2:198655007 A/T cg00792783 chr2:198669748 PLCL1 0.45 6.7 0.34 8.85e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs5753037 0.809 rs5997530 chr22:30203599 C/G cg01021169 chr22:30184971 ASCC2 -0.36 -6.81 -0.35 4.4e-11 Type 1 diabetes; LIHC cis rs11711311 1.000 rs891574 chr3:113537639 C/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 7.72 0.39 1.25e-13 IgG glycosylation; LIHC cis rs959260 1.000 rs4789193 chr17:73404796 A/T cg20590849 chr17:73267439 MIF4GD 0.53 5.72 0.3 2.28e-8 Systemic lupus erythematosus; LIHC cis rs9733 0.596 rs7412396 chr1:150666797 C/T cg18016565 chr1:150552671 MCL1 0.51 9.75 0.47 5.42e-20 Tonsillectomy; LIHC cis rs9921222 0.565 rs10903014 chr16:377623 A/G cg26913058 chr16:419975 MRPL28 -0.49 -7.68 -0.38 1.68e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs903552 0.800 rs12903584 chr15:101999369 G/A cg19295451 chr15:102010161 PCSK6 -0.45 -6.28 -0.32 1.01e-9 Diabetic kidney disease; LIHC cis rs9916302 0.851 rs7225096 chr17:37664443 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC trans rs2832077 0.527 rs2705690 chr21:30239245 T/A cg14791747 chr16:20752902 THUMPD1 -0.69 -10.88 -0.51 7.09e-24 Cognitive test performance; LIHC cis rs1538970 0.962 rs4660301 chr1:45820149 T/A cg05343316 chr1:45956843 TESK2 0.59 8.96 0.44 2.16e-17 Platelet count; LIHC cis rs7020830 0.931 rs3802422 chr9:37097172 G/A cg14294708 chr9:37120828 ZCCHC7 1.13 26.2 0.82 8.95e-84 Schizophrenia; LIHC cis rs6430585 0.527 rs2278731 chr2:136396300 T/C cg07169764 chr2:136633963 MCM6 0.65 8.28 0.41 2.87e-15 Corneal structure; LIHC cis rs3812111 0.727 rs471766 chr6:116461477 C/T cg08036074 chr6:116424633 NT5DC1 0.47 8.1 0.4 9.93e-15 Age-related macular degeneration; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg25107268 chr6:89673349 RNGTT -0.39 -6.1 -0.31 2.85e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2153535 0.580 rs915351 chr6:8442793 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs7131987 0.650 rs12366527 chr12:29474256 C/G cg05697976 chr12:29376483 FAR2 0.31 6.2 0.32 1.62e-9 QT interval; LIHC cis rs1691799 0.899 rs903587 chr12:66746061 C/A cg16791601 chr12:66731901 HELB -0.56 -13.94 -0.6 2.85e-35 White blood cell count (basophil); LIHC cis rs6952808 0.531 rs3778991 chr7:2172455 G/A cg02951883 chr7:2050386 MAD1L1 -0.6 -9.53 -0.46 2.91e-19 Bipolar disorder and schizophrenia; LIHC cis rs798554 0.836 rs798490 chr7:2801542 C/T cg19717773 chr7:2847554 GNA12 -0.4 -6.52 -0.33 2.55e-10 Height; LIHC cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg18279126 chr7:2041391 MAD1L1 0.36 5.81 0.3 1.43e-8 Bipolar disorder and schizophrenia; LIHC cis rs826838 0.935 rs7301104 chr12:39182821 C/T cg13010199 chr12:38710504 ALG10B 0.5 6.02 0.31 4.6e-9 Heart rate; LIHC cis rs2404602 0.698 rs12909656 chr15:76664378 A/T cg03037974 chr15:76606532 NA -0.65 -11.47 -0.53 5.63e-26 Blood metabolite levels; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs9296092 0.538 rs62407567 chr6:33537213 A/G cg13560919 chr6:33536144 NA -0.42 -6.78 -0.34 5.33e-11 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs5769707 1.000 rs5769707 chr22:50013402 G/T cg01652190 chr22:50026171 C22orf34 -0.31 -7.12 -0.36 6.27e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7095944 0.584 rs10901814 chr10:126431281 G/C cg20435097 chr10:126320824 FAM53B 0.38 6.29 0.32 9.7e-10 Asthma; LIHC cis rs875971 0.723 rs28391294 chr7:65654315 T/C cg18252515 chr7:66147081 NA 0.42 5.77 0.3 1.79e-8 Aortic root size; LIHC cis rs4555082 0.874 rs2015978 chr14:105720134 G/C cg10792982 chr14:105748885 BRF1 0.45 6.03 0.31 4.22e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.67 0.42 1.73e-16 Platelet count; LIHC cis rs12474201 0.832 rs6738426 chr2:46986416 A/G cg06386533 chr2:46925753 SOCS5 0.62 7.09 0.36 7.72e-12 Height; LIHC cis rs4853012 0.941 rs60291089 chr2:74344890 T/G cg19729930 chr2:74357872 NA 0.81 17.55 0.69 1.22e-49 Gestational age at birth (maternal effect); LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs250677 0.687 rs250667 chr5:148455134 A/G cg18129178 chr5:148520854 ABLIM3 0.48 7.51 0.38 5.36e-13 Breast cancer; LIHC cis rs4722404 0.739 rs10951044 chr7:3141147 C/T cg19214707 chr7:3157722 NA -0.34 -6.32 -0.32 8.01e-10 Atopic dermatitis; LIHC cis rs4660306 0.961 rs4660871 chr1:45995232 C/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.52 -0.33 2.53e-10 Homocysteine levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25683012 chr12:57030113 BAZ2A 0.44 6.99 0.35 1.41e-11 Pancreatic cancer; LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg09455208 chr3:40491958 NA 0.4 8.12 0.4 8.77e-15 Renal cell carcinoma; LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg05896524 chr21:47604654 C21orf56 -0.49 -7.82 -0.39 6.58e-14 Testicular germ cell tumor; LIHC cis rs6809651 0.524 rs6444106 chr3:185811495 C/T cg00760338 chr3:185826511 ETV5 -0.72 -10.39 -0.49 3.76e-22 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs3106136 0.681 rs13126976 chr4:95303472 G/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs2841277 0.646 rs3742935 chr14:105405599 G/C cg21017887 chr14:105400489 NA 0.66 12.76 0.57 9.24e-31 Rheumatoid arthritis; LIHC cis rs1005277 0.691 rs2474558 chr10:38486141 A/C cg00409905 chr10:38381863 ZNF37A 0.5 7.84 0.39 5.77e-14 Extrinsic epigenetic age acceleration; LIHC cis rs2952156 1.000 rs1810132 chr17:37866005 C/T cg00129232 chr17:37814104 STARD3 -0.5 -9.0 -0.44 1.65e-17 Asthma; LIHC cis rs3806843 0.801 rs2531358 chr5:140117437 A/G cg26395211 chr5:140044315 WDR55 0.4 5.94 0.31 6.9e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1401999 0.966 rs2292998 chr3:183663833 T/C cg05044414 chr3:183734942 ABCC5 0.34 6.07 0.31 3.33e-9 Anterior chamber depth; LIHC cis rs6088590 0.648 rs6059991 chr20:33280836 C/T cg08999081 chr20:33150536 PIGU 0.63 11.68 0.53 9.66e-27 Coronary artery disease; LIHC cis rs5769765 0.955 rs4075330 chr22:50303249 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.76 -9.77 -0.47 4.61e-20 Schizophrenia; LIHC cis rs5167 0.566 rs204905 chr19:45460764 G/A cg13119609 chr19:45449297 APOC2 0.23 6.79 0.34 4.96e-11 Blood protein levels; LIHC cis rs3749237 0.595 rs3870337 chr3:49557095 G/T cg07636037 chr3:49044803 WDR6 0.53 8.15 0.4 6.85e-15 Resting heart rate; LIHC cis rs250677 0.652 rs36042 chr5:148439782 G/T cg23229984 chr5:148520753 ABLIM3 0.51 5.78 0.3 1.68e-8 Breast cancer; LIHC cis rs2573652 1.000 rs2581341 chr15:100514494 T/C cg09918751 chr15:100517450 ADAMTS17 -0.81 -14.6 -0.62 7.19e-38 Height; LIHC cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg02290350 chr8:58132656 NA 0.38 8.02 0.4 1.66e-14 Developmental language disorder (linguistic errors); LIHC trans rs800082 0.698 rs800073 chr3:144347599 G/A cg24215973 chr2:240111563 HDAC4 -0.62 -9.65 -0.46 1.18e-19 Smoking behavior; LIHC cis rs17152411 0.895 rs11245419 chr10:126586392 A/T cg07906193 chr10:126599966 NA 0.44 6.89 0.35 2.74e-11 Height; LIHC cis rs79149102 0.579 rs12593476 chr15:75282092 A/C cg09165964 chr15:75287851 SCAMP5 -0.58 -7.54 -0.38 4.26e-13 Lung cancer; LIHC cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg11645453 chr3:52864694 ITIH4 0.21 5.71 0.3 2.39e-8 Electroencephalogram traits; LIHC cis rs8084351 0.524 rs28444913 chr18:50775332 T/G cg24270629 chr18:50823537 DCC -0.5 -7.54 -0.38 4.3e-13 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs72781680 0.898 rs55657921 chr2:24008091 C/G cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs4824093 0.610 rs3761496 chr22:50246466 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.73 -5.71 -0.3 2.43e-8 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.54 -10.22 -0.48 1.38e-21 Prudent dietary pattern; LIHC cis rs1865760 0.929 rs9358896 chr6:25943197 C/A cg12310025 chr6:25882481 NA -0.41 -6.32 -0.32 8.29e-10 Height; LIHC cis rs4589502 0.512 rs4395023 chr15:67097208 G/A cg12317470 chr15:67143691 NA 0.47 6.19 0.32 1.77e-9 Lung cancer (smoking interaction); LIHC cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg05368731 chr17:41323189 NBR1 0.72 12.13 0.55 2.09e-28 Menopause (age at onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16907344 chr1:16174671 SPEN;FLJ37453 0.41 6.22 0.32 1.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC trans rs983392 0.709 rs2081547 chr11:59989430 C/T cg17275991 chr19:58003312 ZNF419 0.43 6.16 0.32 2e-9 Alzheimer's disease (late onset); LIHC trans rs7615952 0.611 rs2971298 chr3:125602713 G/A cg07211511 chr3:129823064 LOC729375 -0.83 -9.2 -0.45 3.55e-18 Blood pressure (smoking interaction); LIHC cis rs757110 0.745 rs10734252 chr11:17404839 G/A cg15432903 chr11:17409602 KCNJ11 0.67 10.61 0.5 6.36e-23 Type 2 diabetes; LIHC cis rs9596863 0.851 rs9568913 chr13:54340500 A/G ch.13.53330881F chr13:54432880 NA 0.45 6.1 0.31 2.79e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs16944613 0.541 rs10852135 chr15:91106412 T/C cg26821196 chr15:91095069 CRTC3 0.46 7.63 0.38 2.4e-13 Colorectal cancer; LIHC cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg03806693 chr22:41940476 POLR3H -0.99 -10.44 -0.49 2.57e-22 Vitiligo; LIHC cis rs6912958 0.754 rs4587143 chr6:88292291 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.69 -0.38 1.54e-13 Monocyte percentage of white cells; LIHC cis rs13064411 0.696 rs1486897 chr3:113215818 G/A cg18753928 chr3:113234510 CCDC52 -0.43 -6.18 -0.32 1.87e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs1003719 0.762 rs3787787 chr21:38463452 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs4474465 1.000 rs4945281 chr11:78188627 C/G cg02023728 chr11:77925099 USP35 0.32 5.82 0.3 1.38e-8 Alzheimer's disease (survival time); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26399201 chr5:132149404 ANKRD43 -0.39 -6.25 -0.32 1.19e-9 Cognitive function; LIHC cis rs9612 1.000 rs61002661 chr19:44269032 T/A cg08581076 chr19:44259116 C19orf61 0.61 7.52 0.38 4.83e-13 Exhaled nitric oxide output; LIHC cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg22618164 chr12:122356400 WDR66 -0.51 -8.41 -0.41 1.1e-15 Mean corpuscular volume; LIHC cis rs7100689 0.577 rs1340385 chr10:82058851 G/A cg00277334 chr10:82204260 NA -0.56 -6.87 -0.35 3.06e-11 Post bronchodilator FEV1; LIHC cis rs1757171 0.542 rs3818985 chr6:37484214 G/T cg01843034 chr6:37503916 NA -0.46 -7.84 -0.39 5.95e-14 Cognitive performance; LIHC cis rs3849570 0.925 rs2873054 chr3:81888255 A/C cg07356753 chr3:81810745 GBE1 -0.55 -8.7 -0.43 1.37e-16 Waist circumference;Body mass index; LIHC trans rs526821 0.595 rs504661 chr11:55312683 A/G cg03929089 chr4:120376271 NA -0.45 -6.8 -0.35 4.63e-11 Pediatric bone mineral density (spine); LIHC cis rs1728785 1.000 rs11647432 chr16:68565426 C/T cg02972257 chr16:68554789 NA -0.53 -6.19 -0.32 1.73e-9 Ulcerative colitis; LIHC cis rs8044995 0.563 rs3785113 chr16:68369213 T/C cg03983715 chr16:68378420 PRMT7 -0.52 -6.3 -0.32 9.23e-10 Schizophrenia; LIHC cis rs79149102 0.579 rs7166105 chr15:75343942 A/G cg15902774 chr15:75289873 SCAMP5 -0.46 -6.82 -0.35 4.24e-11 Lung cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16020249 chr1:27930640 AHDC1 0.39 6.11 0.31 2.75e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9527 0.662 rs10883783 chr10:104591152 T/A cg15744005 chr10:104629667 AS3MT -0.34 -6.3 -0.32 8.96e-10 Arsenic metabolism; LIHC cis rs9399135 0.660 rs4646868 chr6:135271946 A/G cg22676075 chr6:135203613 NA 0.41 6.51 0.33 2.74e-10 Red blood cell count; LIHC cis rs986417 1.000 rs10130267 chr14:60944527 A/G cg27398547 chr14:60952738 C14orf39 0.78 8.62 0.42 2.6e-16 Gut microbiota (bacterial taxa); LIHC cis rs748404 0.660 rs2444251 chr15:43788595 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.39 0.37 1.15e-12 Lung cancer; LIHC cis rs1475911 1.000 rs55645900 chr21:43515728 G/T cg19766460 chr21:43528205 UMODL1;C21orf128 0.81 11.94 0.54 1.03e-27 IgG glycosylation; LIHC cis rs4407350 0.870 rs5764873 chr22:44908153 G/A cg04154583 chr22:44889756 LDOC1L 0.3 6.0 0.31 4.96e-9 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg03721293 chr16:90014378 DEF8 0.43 7.11 0.36 6.98e-12 Skin colour saturation; LIHC cis rs10751667 0.600 rs1128419 chr11:1010750 G/A cg10932868 chr11:921992 NA 0.32 5.88 0.3 9.9e-9 Alzheimer's disease (late onset); LIHC cis rs3733346 0.553 rs6813110 chr4:942660 C/T cg22718636 chr4:961658 DGKQ 0.34 7.07 0.36 8.88e-12 Sjögren's syndrome; LIHC cis rs9457247 0.765 rs9457249 chr6:167426438 A/G cg07741184 chr6:167504864 NA 0.32 7.32 0.37 1.75e-12 Crohn's disease; LIHC cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg09222892 chr1:25734099 RHCE -0.47 -8.85 -0.43 4.77e-17 Erythrocyte sedimentation rate; LIHC cis rs2645694 0.626 rs2703136 chr4:77828957 T/A cg06046430 chr4:77819534 ANKRD56 0.52 6.42 0.33 4.65e-10 Emphysema distribution in smoking; LIHC cis rs523522 0.924 rs11065150 chr12:120958875 T/G cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04282497 chr4:82350883 RASGEF1B 0.45 6.46 0.33 3.69e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg15691649 chr6:25882328 NA 0.51 7.0 0.35 1.35e-11 Blood metabolite levels; LIHC cis rs4819052 0.851 rs7279182 chr21:46656112 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.5 6.85 0.35 3.45e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2204008 0.840 rs3892363 chr12:38479487 G/A cg13010199 chr12:38710504 ALG10B 0.46 6.14 0.31 2.35e-9 Bladder cancer; LIHC trans rs2243480 1.000 rs7804223 chr7:65664559 T/G cg10756647 chr7:56101905 PSPH -1.04 -12.63 -0.56 2.87e-30 Diabetic kidney disease; LIHC cis rs17685 0.753 rs4398845 chr7:75716781 G/A cg16684958 chr7:75615977 POR 0.48 8.04 0.4 1.5e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1055129 0.655 rs7223416 chr17:73836162 C/G cg19302996 chr17:73780495 UNK -0.59 -9.44 -0.45 5.8e-19 White matter hyperintensity burden; LIHC cis rs1873147 0.569 rs8034365 chr15:63309203 C/T cg05771511 chr15:63340396 TPM1 -0.44 -5.94 -0.31 7.01e-9 Orofacial clefts; LIHC cis rs11212737 0.765 rs2640767 chr11:108518303 A/C cg22776369 chr11:108536276 DDX10 0.38 6.3 0.32 9.31e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs56104184 0.775 rs73061692 chr19:49399676 T/C cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg03264133 chr6:25882463 NA 0.5 6.37 0.33 6.05e-10 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg16405210 chr4:1374714 KIAA1530 0.43 6.43 0.33 4.27e-10 Obesity-related traits; LIHC cis rs908922 0.676 rs7531317 chr1:152528439 A/C cg20991723 chr1:152506922 NA 0.57 9.91 0.47 1.67e-20 Hair morphology; LIHC cis rs7512552 0.839 rs1694362 chr1:150366963 T/A cg15654264 chr1:150340011 RPRD2 0.69 11.4 0.52 9.57e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs992157 0.560 rs7578940 chr2:219083318 G/T cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.03 -0.55 4.75e-28 Colorectal cancer; LIHC trans rs875971 0.545 rs73378304 chr7:65640747 G/A cg26939375 chr7:64535504 NA 0.38 6.11 0.31 2.75e-9 Aortic root size; LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.97 -0.31 5.99e-9 Total body bone mineral density; LIHC trans rs1005277 0.579 rs2505248 chr10:38459097 A/G cg27523141 chr10:43048294 ZNF37B 0.37 6.36 0.33 6.37e-10 Extrinsic epigenetic age acceleration; LIHC cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg27286337 chr10:134555280 INPP5A 0.88 13.13 0.58 3.53e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20913106 chr8:38324522 FGFR1 0.41 6.76 0.34 5.97e-11 Cognitive function; LIHC trans rs1814175 0.534 rs1983448 chr11:49933856 C/A cg18944383 chr4:111397179 ENPEP 0.25 6.32 0.32 8.01e-10 Height; LIHC cis rs1538970 0.924 rs4660855 chr1:45899795 A/G cg05343316 chr1:45956843 TESK2 0.58 8.38 0.41 1.4e-15 Platelet count; LIHC cis rs7762018 1.000 rs7747645 chr6:170070291 G/C cg13891659 chr6:170190454 C6orf122;C6orf208 0.5 5.82 0.3 1.33e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9733 0.596 rs72702585 chr1:150696427 G/A cg17724175 chr1:150552817 MCL1 0.47 9.54 0.46 2.7e-19 Tonsillectomy; LIHC cis rs4845570 1.000 rs6681093 chr1:151755284 C/G cg07092448 chr1:151763213 TDRKH -0.54 -6.86 -0.35 3.27e-11 Coronary artery disease; LIHC cis rs9427116 0.502 rs9427100 chr1:154583762 G/A cg17218026 chr1:154582156 ADAR 0.36 7.19 0.36 3.98e-12 Blood protein levels; LIHC cis rs10416265 0.503 rs1981818 chr19:33615122 C/T cg17764715 chr19:33622953 WDR88 -0.54 -7.57 -0.38 3.39e-13 Bone properties (heel); LIHC cis rs11792861 0.962 rs72607162 chr9:111793719 T/C cg13535736 chr9:111863775 C9orf5 -0.42 -6.42 -0.33 4.67e-10 Menarche (age at onset); LIHC cis rs10479542 0.896 rs10078712 chr5:178978805 C/T cg19723775 chr5:179050963 HNRNPH1 -0.38 -5.96 -0.31 6.44e-9 Lung cancer; LIHC cis rs9902453 1.000 rs9890886 chr17:28391076 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs2625529 0.878 rs16956302 chr15:72136243 C/T cg16672083 chr15:72433130 SENP8 -0.32 -5.95 -0.31 6.6e-9 Red blood cell count; LIHC cis rs7223966 0.621 rs9906747 chr17:61639694 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.54 -5.88 -0.3 9.63e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs425277 1.000 rs421992 chr1:2077260 C/T cg24578937 chr1:2090814 PRKCZ 0.49 8.97 0.44 2.01e-17 Height; LIHC cis rs7777484 0.517 rs2644306 chr7:2831602 A/G cg19717773 chr7:2847554 GNA12 -0.45 -8.87 -0.43 4.22e-17 Height; LIHC cis rs9640161 0.742 rs2159236 chr7:150017214 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.47 -0.42 7.2e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs12079745 0.590 rs41272453 chr1:169412011 T/G cg09363564 chr1:169337483 NME7;BLZF1 -0.75 -6.8 -0.35 4.54e-11 QT interval; LIHC cis rs1005277 0.579 rs2472173 chr10:38374638 G/A cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg06466757 chr4:1255808 NA 0.35 5.86 0.3 1.06e-8 Obesity-related traits; LIHC cis rs6062302 0.522 rs3810492 chr20:62219740 G/A cg06363034 chr20:62225388 GMEB2 -0.43 -7.32 -0.37 1.81e-12 Glioblastoma; LIHC cis rs9733 0.650 rs4970923 chr1:150608300 A/G cg13175981 chr1:150552382 MCL1 0.65 10.21 0.48 1.52e-21 Tonsillectomy; LIHC cis rs9640161 0.658 rs60467296 chr7:150015471 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.45 -7.91 -0.39 3.66e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7927771 0.832 rs10838697 chr11:47384484 T/A cg20135002 chr11:47629003 NA -0.52 -8.78 -0.43 8.09e-17 Subjective well-being; LIHC cis rs9388451 0.626 rs1268074 chr6:126107791 G/C cg05901451 chr6:126070800 HEY2 -0.63 -13.08 -0.58 5.4e-32 Brugada syndrome; LIHC cis rs3960554 0.569 rs10954750 chr7:75664921 C/G cg16684958 chr7:75615977 POR -0.44 -6.77 -0.34 5.69e-11 Eotaxin levels; LIHC cis rs918629 0.761 rs3777175 chr5:95277555 A/G cg10483112 chr5:95245456 ELL2 -0.36 -6.09 -0.31 3.04e-9 IgG glycosylation; LIHC cis rs62458065 0.513 rs787216 chr7:32578891 G/A cg20159608 chr7:32802032 NA -0.51 -6.1 -0.31 2.89e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs2153535 0.563 rs1737585 chr6:8536594 A/G cg21535247 chr6:8435926 SLC35B3 -0.63 -8.21 -0.41 4.59e-15 Motion sickness; LIHC cis rs1580019 0.563 rs13244332 chr7:32537679 G/A cg14728415 chr7:32535168 LSM5;AVL9 0.42 6.07 0.31 3.31e-9 Cognitive ability; LIHC cis rs74233809 1.000 rs11191505 chr10:104766891 C/T cg03493300 chr10:104813866 CNNM2 0.45 6.0 0.31 4.97e-9 Birth weight; LIHC cis rs9549367 0.789 rs6577034 chr13:113879900 T/C cg00898013 chr13:113819073 PROZ -0.36 -6.51 -0.33 2.73e-10 Platelet distribution width; LIHC cis rs34172651 0.917 rs7202252 chr16:24741686 T/C cg00339695 chr16:24857497 SLC5A11 -0.58 -8.91 -0.43 3.03e-17 Intelligence (multi-trait analysis); LIHC cis rs2108225 0.872 rs4618632 chr7:107440952 T/G cg18560240 chr7:107437656 SLC26A3 -0.39 -5.9 -0.3 8.76e-9 Ulcerative colitis; LIHC cis rs250677 0.522 rs1432798 chr5:148383345 C/G cg18129178 chr5:148520854 ABLIM3 -0.4 -6.14 -0.31 2.32e-9 Breast cancer; LIHC cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg09323728 chr8:95962352 TP53INP1 -0.3 -6.33 -0.32 7.73e-10 Type 2 diabetes; LIHC cis rs2710642 0.576 rs1872789 chr2:62883470 A/C cg17519650 chr2:63277830 OTX1 0.52 7.52 0.38 4.73e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs9309473 1.000 rs6745368 chr2:73809974 C/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs9649213 0.531 rs35216698 chr7:97896175 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.39 -5.98 -0.31 5.76e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg05368731 chr17:41323189 NBR1 0.73 12.13 0.55 2e-28 Menopause (age at onset); LIHC cis rs3820500 0.543 rs1290557 chr1:118064763 C/T cg20383390 chr1:117909022 MAN1A2 -0.45 -5.82 -0.3 1.39e-8 Pneumonia; LIHC cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg21724239 chr8:58056113 NA 0.57 7.14 0.36 5.53e-12 Developmental language disorder (linguistic errors); LIHC cis rs8072100 0.837 rs62074055 chr17:45771933 G/C cg08085267 chr17:45401833 C17orf57 -0.54 -7.79 -0.39 8.25e-14 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4423214 1.000 rs12278461 chr11:71182185 C/T cg24826892 chr11:71159390 DHCR7 0.47 6.1 0.31 2.86e-9 Vitamin D levels; LIHC cis rs4979906 1.000 rs11002247 chr10:79446901 T/C cg07817648 chr10:79422355 NA -0.29 -6.34 -0.32 7.44e-10 Mortality in heart failure; LIHC cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg00484396 chr16:3507460 NAT15 -0.41 -7.18 -0.36 4.31e-12 Tuberculosis; LIHC cis rs7727544 0.709 rs441969 chr5:131702120 G/A cg24060327 chr5:131705240 SLC22A5 -0.58 -8.29 -0.41 2.53e-15 Blood metabolite levels; LIHC cis rs7927592 0.913 rs11228262 chr11:68274907 G/T cg01657329 chr11:68192670 LRP5 -0.46 -6.02 -0.31 4.6e-9 Total body bone mineral density; LIHC cis rs6746896 0.843 rs72809827 chr2:97390953 C/T cg26665480 chr2:98280029 ACTR1B 0.45 5.85 0.3 1.14e-8 Bipolar disorder; LIHC cis rs11761441 0.602 rs6979396 chr7:93116 G/A cg25149888 chr7:81075 NA -0.26 -5.72 -0.3 2.33e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs919433 0.926 rs787997 chr2:198216271 A/G cg10820045 chr2:198174542 NA 0.52 8.73 0.43 1.15e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg04546413 chr19:29218101 NA 0.41 8.14 0.4 7.37e-15 Methadone dose in opioid dependence; LIHC cis rs36051895 0.664 rs7847141 chr9:5097171 A/T cg02405213 chr9:5042618 JAK2 -0.68 -11.66 -0.53 1.1e-26 Pediatric autoimmune diseases; LIHC cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg00080972 chr5:178986291 RUFY1 -0.38 -5.71 -0.3 2.42e-8 Lung cancer; LIHC cis rs713477 0.654 rs7143800 chr14:55917734 A/G cg13175173 chr14:55914753 NA -0.31 -7.05 -0.36 9.64e-12 Pediatric bone mineral content (femoral neck); LIHC cis rs787274 0.543 rs10739377 chr9:115631598 A/G cg13803584 chr9:115635662 SNX30 0.62 9.44 0.45 5.92e-19 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs11711311 1.000 rs1073040 chr3:113522123 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.08 -0.36 8.24e-12 IgG glycosylation; LIHC cis rs9486719 1.000 rs12197411 chr6:97039621 G/A cg18709589 chr6:96969512 KIAA0776 -0.47 -5.76 -0.3 1.83e-8 Migraine;Coronary artery disease; LIHC cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg25072359 chr17:41440525 NA 0.39 6.14 0.32 2.26e-9 Menopause (age at onset); LIHC trans rs875971 0.964 rs6978429 chr7:65959876 T/G cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.09e-10 Aortic root size; LIHC trans rs1499280 1.000 rs1499280 chr5:52096889 C/A cg23271318 chr20:44509620 ZSWIM1 -0.66 -6.35 -0.32 6.68e-10 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs2404602 0.692 rs7350777 chr15:76985441 G/A cg23625390 chr15:77176239 SCAPER 0.36 5.94 0.31 6.92e-9 Blood metabolite levels; LIHC cis rs9467773 1.000 rs1056667 chr6:26510564 T/C cg09904177 chr6:26538194 HMGN4 0.66 13.85 0.6 6.03e-35 Intelligence (multi-trait analysis); LIHC trans rs9914544 1.000 rs1037036 chr17:18764077 C/T cg21372672 chr17:16614065 CCDC144A -0.29 -6.54 -0.33 2.19e-10 Educational attainment (years of education); LIHC cis rs250677 0.652 rs168751 chr5:148438264 C/T cg23229984 chr5:148520753 ABLIM3 0.51 5.78 0.3 1.68e-8 Breast cancer; LIHC cis rs2204008 0.744 rs8189486 chr12:38244968 C/T cg26384229 chr12:38710491 ALG10B 0.87 10.83 0.51 1.06e-23 Bladder cancer; LIHC cis rs1775715 0.707 rs2808079 chr10:32167385 C/T cg14930904 chr10:32216787 ARHGAP12 0.36 6.27 0.32 1.07e-9 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs2727020 0.521 rs1909220 chr11:49572109 T/C cg15704280 chr7:45808275 SEPT13 -0.79 -11.94 -0.54 1.08e-27 Coronary artery disease; LIHC cis rs760805 1.000 rs7517302 chr1:25254317 C/T cg22509179 chr1:25234806 RUNX3 -0.38 -7.94 -0.39 2.97e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1185460 0.967 rs4545564 chr11:118937518 T/C cg23280166 chr11:118938394 VPS11 0.6 8.31 0.41 2.35e-15 Coronary artery disease; LIHC cis rs1215050 0.791 rs165254 chr4:98763564 C/T cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs11165623 0.792 rs12123543 chr1:96964549 T/C cg10631902 chr5:14652156 NA -0.29 -6.79 -0.34 4.95e-11 Hip circumference;Waist circumference; LIHC cis rs9325144 0.534 rs6582538 chr12:38629997 A/C cg26384229 chr12:38710491 ALG10B -0.5 -7.61 -0.38 2.61e-13 Morning vs. evening chronotype; LIHC cis rs57927100 0.734 rs1436138 chr17:75316880 A/G cg18271897 chr17:75316784 SEPT9 0.36 7.17 0.36 4.78e-12 Systolic blood pressure; LIHC trans rs875971 0.545 rs10950036 chr7:65818228 G/T cg26939375 chr7:64535504 NA 0.41 6.49 0.33 3.11e-10 Aortic root size; LIHC trans rs877282 0.628 rs11253435 chr10:824169 T/C cg22713356 chr15:30763199 NA 0.84 7.46 0.37 7.12e-13 Uric acid levels; LIHC cis rs4759375 1.000 rs3088303 chr12:123779489 G/A cg00376283 chr12:123451042 ABCB9 -0.49 -6.31 -0.32 8.53e-10 HDL cholesterol; LIHC cis rs711245 0.748 rs2276671 chr2:36771701 C/A cg15105969 chr2:36825350 FEZ2 0.49 5.86 0.3 1.08e-8 Height; LIHC cis rs9948 1.000 rs62152790 chr2:97478579 G/A cg01990225 chr2:97406019 LMAN2L -0.68 -6.25 -0.32 1.23e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg02244288 chr16:89573955 SPG7 -0.31 -6.12 -0.31 2.61e-9 Multiple myeloma (IgH translocation); LIHC cis rs1577917 0.958 rs12190603 chr6:86475718 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.32 -5.77 -0.3 1.82e-8 Response to antipsychotic treatment; LIHC cis rs6088580 0.524 rs7269596 chr20:33229063 T/C cg08999081 chr20:33150536 PIGU -0.43 -7.41 -0.37 1.01e-12 Glomerular filtration rate (creatinine); LIHC cis rs6754311 0.593 rs10186843 chr2:136586958 C/A cg15123519 chr2:136567270 LCT 0.45 9.22 0.45 3.04e-18 Mosquito bite size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23477257 chr7:77469577 PHTF2 0.29 6.13 0.31 2.47e-9 Cognitive function; LIHC cis rs2731664 0.792 rs2545795 chr5:176887106 A/C cg23176889 chr5:176863531 GRK6 -0.72 -12.62 -0.56 2.99e-30 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg00800038 chr16:89945340 TCF25 -0.69 -10.96 -0.51 3.81e-24 Skin colour saturation; LIHC cis rs3749237 0.595 rs3924462 chr3:49524236 T/G cg02487422 chr3:49467188 NICN1 0.41 6.32 0.32 8.18e-10 Resting heart rate; LIHC cis rs1419980 0.730 rs11054872 chr12:7770908 C/T cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs4561483 0.831 rs33648 chr16:11979622 G/A cg08843971 chr16:11963173 GSPT1 -0.34 -6.7 -0.34 8.53e-11 Testicular germ cell tumor; LIHC cis rs2070488 0.804 rs13063978 chr3:38476538 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.31 0.55 4.45e-29 Electrocardiographic conduction measures; LIHC trans rs4650994 0.505 rs2811291 chr1:178574217 C/T cg05059571 chr16:84539110 KIAA1609 0.43 7.21 0.36 3.5e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10411936 1.000 rs16995422 chr19:16519045 A/G cg10248733 chr19:16607483 C19orf44;CALR3 -0.43 -5.81 -0.3 1.41e-8 White blood cell count;Multiple sclerosis; LIHC cis rs11583043 1.000 rs7535068 chr1:101490329 T/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.06 0.31 3.55e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs6754311 0.509 rs3820794 chr2:136505546 C/T cg25344623 chr2:136566232 LCT 0.34 6.44 0.33 4.06e-10 Mosquito bite size; LIHC cis rs10911251 0.509 rs4652780 chr1:183105923 G/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.33 0.49 6.11e-22 Colorectal cancer; LIHC cis rs7592578 0.713 rs60915953 chr2:191331304 G/C cg10560079 chr2:191398806 TMEM194B -0.87 -12.23 -0.55 8.6e-29 Diastolic blood pressure; LIHC cis rs240764 0.631 rs9386250 chr6:101204126 A/G cg09795085 chr6:101329169 ASCC3 -0.41 -5.75 -0.3 2.01e-8 Neuroticism; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20545544 chr12:54673867 CBX5;HNRNPA1;HNRPA1L-2 0.44 6.94 0.35 2.01e-11 Calcium levels; LIHC trans rs3960554 0.932 rs11971220 chr7:75842792 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 6.94 0.35 1.94e-11 Eotaxin levels; LIHC cis rs6951245 1.000 rs79443843 chr7:1075245 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.73e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4517514 0.509 rs10830411 chr11:89865532 A/G cg05041596 chr11:89867385 NAALAD2 0.41 6.51 0.33 2.63e-10 Trans fatty acid levels; LIHC cis rs4908760 0.613 rs12028160 chr1:8812214 A/G cg20416874 chr1:8611966 RERE 0.55 9.2 0.45 3.51e-18 Vitiligo; LIHC cis rs875971 0.862 rs937494 chr7:65764678 T/A cg18252515 chr7:66147081 NA 0.44 6.33 0.32 7.52e-10 Aortic root size; LIHC cis rs2963155 0.518 rs72801080 chr5:142751990 T/C cg17617527 chr5:142782415 NR3C1 0.89 8.0 0.4 1.93e-14 Breast cancer; LIHC cis rs9916302 0.904 rs801419 chr17:37466327 A/G cg07936489 chr17:37558343 FBXL20 0.81 12.98 0.57 1.4e-31 Glomerular filtration rate (creatinine); LIHC cis rs1816752 0.712 rs6490932 chr13:25017451 A/G cg22771759 chr13:24902376 NA 0.31 6.47 0.33 3.49e-10 Obesity-related traits; LIHC cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg05590025 chr7:65112418 INTS4L2 -0.62 -6.81 -0.35 4.45e-11 Diabetic kidney disease; LIHC cis rs7412746 0.658 rs72704652 chr1:150819470 A/G cg18016565 chr1:150552671 MCL1 0.55 10.23 0.48 1.32e-21 Melanoma; LIHC trans rs1814175 0.817 rs1988416 chr11:49932324 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs4919694 0.901 rs113541728 chr10:104716771 A/T cg04362960 chr10:104952993 NT5C2 1.13 8.8 0.43 6.86e-17 Arsenic metabolism; LIHC trans rs3783890 1.000 rs12884084 chr14:93762704 A/G cg02802420 chr16:69363236 PDF;COG8 0.32 6.21 0.32 1.5e-9 Body mass index; LIHC cis rs17401966 0.838 rs11121551 chr1:10435170 T/C cg19773385 chr1:10388646 KIF1B -0.39 -6.9 -0.35 2.54e-11 Hepatocellular carcinoma; LIHC cis rs3806843 0.735 rs813897 chr5:140070029 T/C cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg25036284 chr2:26402008 FAM59B -0.52 -5.79 -0.3 1.62e-8 Gut microbiome composition (summer); LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg21003380 chr1:156261207 TMEM79 0.38 6.0 0.31 5.08e-9 Tonsillectomy; LIHC cis rs919433 0.726 rs11904247 chr2:198238424 T/G cg03934865 chr2:198174659 NA 0.54 8.14 0.4 7.24e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11864453 0.647 rs3852781 chr16:72123556 T/A cg16558253 chr16:72132732 DHX38 -0.44 -7.25 -0.36 2.88e-12 Fibrinogen levels; LIHC cis rs4638749 0.677 rs10174695 chr2:108842164 G/A cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs11671005 0.611 rs35138622 chr19:58912788 C/A cg25952890 chr19:58913133 NA 0.66 6.48 0.33 3.27e-10 Mean platelet volume; LIHC cis rs4803468 1.000 rs2241708 chr19:41912270 C/T cg09537434 chr19:41945824 ATP5SL -1.0 -20.3 -0.74 1.06e-60 Height; LIHC cis rs5769765 0.955 rs1321 chr22:50297435 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.23 -0.45 2.79e-18 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23453437 chr7:148892747 ZNF282 0.52 6.78 0.34 5.17e-11 Lung function (FEV1/FVC); LIHC cis rs6545883 0.826 rs1186697 chr2:61661417 G/A cg14146966 chr2:61757674 XPO1 0.45 7.63 0.38 2.43e-13 Tuberculosis; LIHC cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg02290350 chr8:58132656 NA 0.44 8.57 0.42 3.49e-16 Developmental language disorder (linguistic errors); LIHC cis rs1816752 0.905 rs9511266 chr13:25012504 C/G cg02811702 chr13:24901961 NA 0.26 6.63 0.34 1.32e-10 Obesity-related traits; LIHC cis rs12477438 1.000 rs1922624 chr2:99909958 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.91 -11.08 -0.51 1.37e-24 Chronic sinus infection; LIHC cis rs11663156 1.000 rs10515961 chr18:50931238 A/G cg24270629 chr18:50823537 DCC -0.48 -6.62 -0.34 1.36e-10 Intelligence (multi-trait analysis); LIHC cis rs68170813 0.559 rs10953530 chr7:106827796 A/C cg02696742 chr7:106810147 HBP1 -0.54 -6.11 -0.31 2.68e-9 Coronary artery disease; LIHC cis rs17376456 0.877 rs10213956 chr5:93460839 C/T cg25358565 chr5:93447407 FAM172A 1.12 10.35 0.49 5.17e-22 Diabetic retinopathy; LIHC cis rs10847980 0.590 rs1979237 chr12:123325895 C/T cg18912006 chr12:123335444 HIP1R 0.77 7.92 0.39 3.46e-14 Adiponectin levels; LIHC cis rs1577917 0.917 rs35038582 chr6:86721305 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.25 -0.48 1.16e-21 Response to antipsychotic treatment; LIHC cis rs10751667 0.666 rs7396059 chr11:970490 C/A cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs7927592 0.913 rs3758643 chr11:68367193 C/T cg20283391 chr11:68216788 NA -0.51 -7.67 -0.38 1.76e-13 Total body bone mineral density; LIHC trans rs11098499 0.738 rs10026493 chr4:120384194 C/G cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs6754311 0.552 rs1030765 chr2:136553188 A/T cg25344623 chr2:136566232 LCT 0.44 8.36 0.41 1.6e-15 Mosquito bite size; LIHC cis rs7296418 0.961 rs1790106 chr12:123591596 G/T cg00376283 chr12:123451042 ABCB9 0.74 13.06 0.58 6.51e-32 Platelet count; LIHC cis rs797680 0.586 rs2281525 chr1:93595306 G/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.38 -6.57 -0.33 1.85e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs2075371 0.933 rs2244548 chr7:133986234 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC cis rs904251 1.000 rs12212090 chr6:37431808 A/G cg01843034 chr6:37503916 NA -0.39 -6.47 -0.33 3.36e-10 Cognitive performance; LIHC cis rs10256972 0.521 rs7457418 chr7:1110255 C/T cg07308232 chr7:1071921 C7orf50 -0.47 -7.21 -0.36 3.51e-12 Longevity;Endometriosis; LIHC trans rs11157436 0.830 rs61972214 chr14:22620372 T/C cg13567813 chr19:50879636 NR1H2 0.42 6.12 0.31 2.56e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs3096299 0.935 rs3114890 chr16:89449546 C/G cg01788221 chr16:89496183 ANKRD11 -0.43 -6.5 -0.33 2.81e-10 Multiple myeloma (IgH translocation); LIHC cis rs769267 0.930 rs7256149 chr19:19566255 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.04 0.31 4.13e-9 Tonsillectomy; LIHC cis rs4906332 0.966 rs7159665 chr14:103984616 C/T cg19000871 chr14:103996768 TRMT61A -0.47 -7.75 -0.39 1.08e-13 Coronary artery disease; LIHC cis rs4665809 1.000 rs11678157 chr2:26321526 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.89 -0.43 3.51e-17 Gut microbiome composition (summer); LIHC cis rs4660306 0.961 rs4660860 chr1:45946233 T/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.65 -7.77 -0.39 9.35e-14 Homocysteine levels; LIHC cis rs7395581 0.959 rs2279239 chr11:47281780 T/C cg25783544 chr11:47291846 MADD 0.45 6.66 0.34 1.06e-10 HDL cholesterol; LIHC cis rs4407350 0.756 rs6519877 chr22:44890192 T/G cg11695653 chr22:44894386 LDOC1L -0.38 -6.41 -0.33 4.83e-10 Intelligence (multi-trait analysis); LIHC cis rs4727027 0.736 rs12704084 chr7:148915050 C/G cg23583168 chr7:148888333 NA -0.65 -10.23 -0.48 1.36e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs507080 0.922 rs525485 chr11:118555754 C/T cg04173919 chr11:118528438 PHLDB1 0.35 6.52 0.33 2.51e-10 Serum metabolite levels; LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg00656387 chr3:40428638 ENTPD3 0.51 8.52 0.42 5.17e-16 Renal cell carcinoma; LIHC cis rs7523273 0.606 rs859705 chr1:207959665 A/G cg22525895 chr1:207977042 MIR29B2 0.61 9.92 0.47 1.47e-20 Schizophrenia; LIHC cis rs1707322 1.000 rs1612419 chr1:46546945 T/C cg06784218 chr1:46089804 CCDC17 -0.4 -7.23 -0.36 3.18e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9641123 0.669 rs2677096 chr7:93246497 T/C cg09745688 chr16:2908918 PRSS22 -0.36 -6.34 -0.32 7.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs751728 0.965 rs9394168 chr6:33759701 T/A cg25922239 chr6:33757077 LEMD2 0.43 7.23 0.36 3.24e-12 Crohn's disease; LIHC cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg04267008 chr7:1944627 MAD1L1 -0.66 -10.72 -0.5 2.63e-23 Bipolar disorder and schizophrenia; LIHC cis rs6570726 0.935 rs379164 chr6:145829093 A/T cg23711669 chr6:146136114 FBXO30 0.55 9.8 0.47 3.77e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7613875 0.521 rs4688754 chr3:50074641 G/T cg21467203 chr3:49911342 NA 0.5 9.13 0.44 6.05e-18 Body mass index; LIHC cis rs4665809 0.887 rs4665814 chr2:26273687 G/T cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.66 -0.42 1.91e-16 Gut microbiome composition (summer); LIHC cis rs11792861 0.890 rs2900481 chr9:111831825 G/A cg05043794 chr9:111880884 C9orf5 -0.29 -6.7 -0.34 8.54e-11 Menarche (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01630567 chr9:26892919 C9orf82 0.42 6.09 0.31 3.08e-9 Cognitive function; LIHC cis rs7703744 0.747 rs7707470 chr5:118680273 G/A cg10911160 chr5:118691794 TNFAIP8 -0.49 -5.74 -0.3 2.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7914558 0.646 rs7909286 chr10:104658992 A/G cg15744005 chr10:104629667 AS3MT -0.35 -7.2 -0.36 3.87e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs910316 0.934 rs8006587 chr14:75664939 A/G cg08847533 chr14:75593920 NEK9 0.81 16.59 0.67 8.76e-46 Height; LIHC cis rs9309711 0.666 rs11127430 chr2:3485242 G/C cg15506890 chr2:3487001 NA -0.48 -7.65 -0.38 2.08e-13 Neurofibrillary tangles; LIHC cis rs7508 0.546 rs382752 chr8:17898383 A/G cg01800426 chr8:17659068 MTUS1 0.4 6.52 0.33 2.47e-10 Atrial fibrillation; LIHC cis rs4555082 0.834 rs2816653 chr14:105713973 A/G cg06808227 chr14:105710500 BRF1 -0.61 -8.32 -0.41 2.09e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs7772486 0.875 rs7767660 chr6:146436550 T/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.73 -0.3 2.17e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4466137 0.904 rs6887104 chr5:83003535 G/A cg16102102 chr5:83017553 HAPLN1 -0.57 -8.3 -0.41 2.5e-15 Prostate cancer; LIHC cis rs16958440 0.867 rs75901436 chr18:44689644 C/T cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs12893668 0.703 rs4906338 chr14:104050357 A/G cg19000871 chr14:103996768 TRMT61A -0.44 -7.23 -0.36 3.09e-12 Reticulocyte count; LIHC trans rs11098499 0.754 rs4443261 chr4:120249301 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.27 0.41 3.06e-15 Corneal astigmatism; LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg10411590 chr13:21900810 NA 0.42 6.92 0.35 2.29e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg19819135 chr1:70710422 SFRS11 0.38 6.76 0.34 6.01e-11 Colonoscopy-negative controls vs population controls; LIHC trans rs1814175 0.754 rs7103235 chr11:49699191 A/G cg03929089 chr4:120376271 NA -0.77 -12.45 -0.56 1.34e-29 Height; LIHC cis rs9733 0.544 rs2867302 chr1:150653650 T/C cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Tonsillectomy; LIHC cis rs713477 0.845 rs4898863 chr14:55910284 T/A cg13175173 chr14:55914753 NA -0.33 -7.53 -0.38 4.56e-13 Pediatric bone mineral content (femoral neck); LIHC cis rs8062405 0.964 rs62036614 chr16:28824685 T/C cg00204512 chr16:28754710 NA 0.38 6.9 0.35 2.55e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2204008 0.805 rs11514348 chr12:38243427 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.81 0.5 1.29e-23 Bladder cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11037719 chr6:2999695 NQO2 0.49 6.96 0.35 1.71e-11 Pancreatic cancer; LIHC cis rs10857712 0.950 rs7906765 chr10:135225460 G/T cg15472797 chr10:135243109 NA -0.39 -5.87 -0.3 1.03e-8 Systemic lupus erythematosus; LIHC cis rs2732480 0.577 rs2732466 chr12:48732459 A/G cg21466736 chr12:48725269 NA -0.73 -11.14 -0.52 8.5e-25 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg14257396 chr1:107603778 NA 0.36 5.84 0.3 1.23e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4975709 0.589 rs931508 chr5:1861224 C/G cg15595755 chr5:1867978 NA 0.4 8.21 0.41 4.49e-15 Cardiovascular disease risk factors; LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg20295408 chr7:1910781 MAD1L1 0.42 6.27 0.32 1.09e-9 Bipolar disorder and schizophrenia; LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg21248554 chr2:27665150 KRTCAP3 -0.43 -5.83 -0.3 1.3e-8 Total body bone mineral density; LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg09455208 chr3:40491958 NA 0.39 7.93 0.39 3.13e-14 Renal cell carcinoma; LIHC cis rs34779708 0.931 rs4007289 chr10:35269790 G/A cg03585969 chr10:35415529 CREM 0.84 12.81 0.57 5.68e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3540 0.533 rs12916560 chr15:91056259 A/C cg22089800 chr15:90895588 ZNF774 -0.55 -7.76 -0.39 9.73e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs57590327 0.679 rs34880320 chr3:81510666 T/C cg07356753 chr3:81810745 GBE1 -0.42 -5.73 -0.3 2.15e-8 Extraversion; LIHC cis rs7772486 0.720 rs702320 chr6:146006654 G/A cg13319975 chr6:146136371 FBXO30 0.41 6.81 0.35 4.41e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2191566 0.691 rs59086054 chr19:44549096 C/A cg20607764 chr19:44506953 ZNF230 -0.37 -6.22 -0.32 1.45e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs1062177 0.826 rs2915873 chr5:151156658 G/A cg00977110 chr5:151150581 G3BP1 0.54 6.88 0.35 2.9100000000000002e-11 Preschool internalizing problems; LIHC cis rs7927771 0.864 rs55927797 chr11:47446292 A/T cg20307385 chr11:47447363 PSMC3 -0.48 -6.15 -0.32 2.11e-9 Subjective well-being; LIHC cis rs2710642 0.721 rs6727888 chr2:62887884 T/C cg17519650 chr2:63277830 OTX1 0.44 6.41 0.33 4.95e-10 LDL cholesterol levels;LDL cholesterol; LIHC cis rs611744 0.573 rs629996 chr8:109255206 C/T cg21045802 chr8:109455806 TTC35 0.63 11.24 0.52 3.83e-25 Dupuytren's disease; LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg12064134 chr16:90016061 DEF8 -0.43 -5.82 -0.3 1.34e-8 Skin colour saturation; LIHC cis rs2075371 0.897 rs10488428 chr7:133997560 C/T cg20476274 chr7:133979776 SLC35B4 0.72 9.67 0.46 1.06e-19 Mean platelet volume; LIHC cis rs1348850 0.914 rs10497503 chr2:178371739 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.83 12.9 0.57 2.73e-31 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01565824 chr17:79361553 NA -0.35 -6.1 -0.31 2.8e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs801193 0.935 rs2659899 chr7:66186721 A/G cg11764359 chr7:65958608 NA 0.71 10.72 0.5 2.6e-23 Aortic root size; LIHC cis rs10876993 0.855 rs10877007 chr12:58100058 T/A cg15848620 chr12:58087721 OS9 -0.56 -7.54 -0.38 4.31e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.31 -0.61 9.82e-37 Alzheimer's disease; LIHC cis rs3749237 0.595 rs4855873 chr3:49459114 A/C cg02487422 chr3:49467188 NICN1 0.42 6.57 0.33 1.9e-10 Resting heart rate; LIHC cis rs2842992 0.789 rs2475566 chr6:160148741 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.71 12.48 0.56 1.05e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs3789045 0.774 rs11801299 chr1:204529084 G/A cg17419461 chr1:204415978 PIK3C2B -0.42 -6.49 -0.33 2.93e-10 Educational attainment (college completion); LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg11060661 chr22:24314208 DDT;DDTL 0.62 10.81 0.5 1.26e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs208520 0.802 rs208516 chr6:66946119 T/C cg07460842 chr6:66804631 NA -0.7 -7.69 -0.38 1.63e-13 Exhaled nitric oxide output; LIHC cis rs7904368 0.754 rs7076779 chr10:16852667 C/T cg14835575 chr10:16859367 RSU1 0.6 8.78 0.43 7.99e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs4843747 0.708 rs11866437 chr16:88072279 A/G cg00677901 chr16:88017247 BANP -0.62 -9.26 -0.45 2.26e-18 Menopause (age at onset); LIHC cis rs1799949 0.965 rs799908 chr17:41278916 A/G cg05368731 chr17:41323189 NBR1 0.67 11.1 0.51 1.22e-24 Menopause (age at onset); LIHC cis rs116095464 0.867 rs10074958 chr5:230828 C/T cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs8014204 0.967 rs1319171 chr14:75334096 G/T cg08847533 chr14:75593920 NEK9 -0.37 -6.04 -0.31 3.93e-9 Caffeine consumption; LIHC cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 9.57 0.46 2.27e-19 Platelet count; LIHC cis rs2279817 0.735 rs12075624 chr1:17991573 A/G cg21791023 chr1:18019539 ARHGEF10L -0.44 -5.8 -0.3 1.52e-8 Neuroticism; LIHC cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg18230493 chr5:56204884 C5orf35 -0.44 -6.21 -0.32 1.55e-9 Initial pursuit acceleration; LIHC cis rs1577917 0.958 rs12196230 chr6:86519960 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.42 -0.41 1.05e-15 Response to antipsychotic treatment; LIHC cis rs3099143 0.901 rs28551558 chr15:77234637 C/T cg21673338 chr15:77095150 SCAPER -0.49 -6.94 -0.35 1.93e-11 Recalcitrant atopic dermatitis; LIHC cis rs7089973 0.604 rs7897937 chr10:116591318 A/G cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs910316 1.000 rs175426 chr14:75624134 C/T cg11812906 chr14:75593930 NEK9 -0.73 -14.45 -0.62 2.78e-37 Height; LIHC cis rs7927592 0.913 rs3740631 chr11:68341722 T/G cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.94e-14 Total body bone mineral density; LIHC cis rs2777491 0.872 rs61037359 chr15:41585926 T/C cg18705301 chr15:41695430 NDUFAF1 -0.56 -8.55 -0.42 4.09e-16 Ulcerative colitis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg27196102 chr16:23464713 COG7 -0.48 -6.38 -0.33 5.79e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1005277 0.579 rs1780130 chr10:38485378 T/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.56 -0.46 2.36e-19 Extrinsic epigenetic age acceleration; LIHC cis rs367615 0.552 rs7720036 chr5:108710699 A/G cg17395555 chr5:108820864 NA -0.29 -6.21 -0.32 1.54e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg05025164 chr4:1340916 KIAA1530 -0.53 -8.37 -0.41 1.48e-15 Obesity-related traits; LIHC trans rs2270927 0.510 rs35930860 chr5:75579946 T/C cg13563193 chr19:33072644 PDCD5 0.97 9.06 0.44 9.9e-18 Mean corpuscular volume; LIHC cis rs1534166 0.507 rs8177191 chr3:133468139 A/G cg16262614 chr3:133464971 TF 0.37 5.88 0.3 9.8e-9 Alcohol consumption (transferrin glycosylation); LIHC cis rs2820292 1.000 rs2494112 chr1:201787833 G/A cg11586189 chr1:201857591 SHISA4 0.42 6.19 0.32 1.69e-9 Waist circumference;Body mass index (joint analysis main effects and smoking interaction);Body mass index;BMI in non-smokers;BMI (adjusted for smoking behaviour); LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs546131 0.928 rs547504 chr11:34847225 G/T cg06937548 chr11:34938143 PDHX;APIP 0.59 7.99 0.4 2.15e-14 Lung disease severity in cystic fibrosis; LIHC cis rs8067354 0.645 rs9901606 chr17:57811407 A/C cg02344993 chr17:57696989 CLTC 0.7 11.9 0.54 1.51e-27 Hemoglobin concentration; LIHC cis rs7772486 0.790 rs9386141 chr6:146268623 T/A cg23711669 chr6:146136114 FBXO30 -0.62 -10.92 -0.51 4.99e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.646 rs10882924 chr10:99159304 T/A cg20016023 chr10:99160130 RRP12 -0.43 -6.81 -0.35 4.27e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs9457247 0.602 rs2239827 chr6:167490945 G/A cg07741184 chr6:167504864 NA 0.34 7.49 0.38 5.92e-13 Crohn's disease; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg18538332 chr22:24372958 LOC391322 -0.63 -9.3 -0.45 1.66e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs798554 0.567 rs1182190 chr7:2869391 A/G cg19717773 chr7:2847554 GNA12 -0.33 -5.81 -0.3 1.44e-8 Height; LIHC cis rs4742903 0.935 rs4587392 chr9:106972508 G/A cg14250997 chr9:106856677 SMC2 0.34 5.73 0.3 2.19e-8 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs7552404 0.883 rs77773255 chr1:76217193 G/A cg03433033 chr1:76189801 ACADM 0.65 9.18 0.44 4.29e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4148883 0.629 rs2602899 chr4:100010128 C/T cg12011299 chr4:100065546 ADH4 0.35 7.14 0.36 5.5e-12 Alcohol dependence; LIHC trans rs800082 0.674 rs4618255 chr3:144198658 A/G cg24215973 chr2:240111563 HDAC4 0.44 6.62 0.34 1.38e-10 Smoking behavior; LIHC cis rs2279817 0.691 rs7543007 chr1:17990475 A/G cg21791023 chr1:18019539 ARHGEF10L -0.42 -5.91 -0.3 8.31e-9 Neuroticism; LIHC cis rs6565180 0.888 rs8060853 chr16:30403858 A/G cg17640201 chr16:30407289 ZNF48 0.78 12.71 0.57 1.38e-30 Tonsillectomy; LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg06420487 chr17:61919686 SMARCD2 0.45 6.14 0.32 2.31e-9 Height; LIHC cis rs5753618 0.561 rs5753521 chr22:31638027 T/C cg22777020 chr22:31556080 RNF185 -0.55 -6.31 -0.32 8.82e-10 Colorectal cancer; LIHC cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg27572855 chr1:25598939 RHD -0.38 -8.13 -0.4 7.79e-15 Erythrocyte sedimentation rate; LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg02993280 chr1:107599747 PRMT6 0.6 9.04 0.44 1.16e-17 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4713118 0.955 rs9380011 chr6:27683924 A/G cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC cis rs9560113 0.919 rs11069896 chr13:112178887 C/T cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs9430161 0.611 rs2095920 chr1:11033457 T/A cg27631724 chr1:11040367 C1orf127 0.37 6.83 0.35 4.01e-11 Ewing sarcoma; LIHC cis rs870825 0.616 rs2130394 chr4:185642577 C/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs2153535 0.580 rs9406143 chr6:8444583 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg26752003 chr8:145688521 CYHR1 0.62 9.93 0.47 1.42e-20 Age at first birth; LIHC cis rs8017423 0.967 rs8015510 chr14:90729984 C/T cg14092571 chr14:90743983 NA -0.41 -6.53 -0.33 2.34e-10 Mortality in heart failure; LIHC cis rs477692 0.673 rs487120 chr10:131367552 C/T cg05714579 chr10:131428358 MGMT 0.44 7.07 0.36 8.92e-12 Response to temozolomide; LIHC cis rs7818688 0.591 rs10098025 chr8:95989583 T/A cg16049864 chr8:95962084 TP53INP1 0.58 6.42 0.33 4.66e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7086627 0.515 rs10887900 chr10:82210265 A/G cg01528321 chr10:82214614 TSPAN14 0.47 6.66 0.34 1.08e-10 Post bronchodilator FEV1; LIHC cis rs9733 0.596 rs12085275 chr1:150650265 T/C cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Tonsillectomy; LIHC cis rs4665809 1.000 rs2289022 chr2:26350136 G/T cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs9388451 0.626 rs1343116 chr6:126069702 C/A cg05901451 chr6:126070800 HEY2 -0.69 -14.61 -0.62 6.62e-38 Brugada syndrome; LIHC cis rs919433 0.679 rs61155920 chr2:198528881 C/T cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs5770917 1.000 rs762676 chr22:51017794 A/G cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.51 -6.92 -0.35 2.19e-11 Narcolepsy; LIHC cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC cis rs4819052 0.765 rs2838868 chr21:46714641 A/G cg22633049 chr21:46681294 NA 0.39 6.04 0.31 4e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs950776 0.518 rs8053 chr15:78841220 T/C cg22563815 chr15:78856949 CHRNA5 -0.37 -6.94 -0.35 1.92e-11 Sudden cardiac arrest; LIHC cis rs477895 0.941 rs12808002 chr11:64110932 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 6.76 0.34 6.01e-11 Mean platelet volume; LIHC cis rs6570726 0.791 rs9376953 chr6:145912226 G/T cg13319975 chr6:146136371 FBXO30 -0.42 -6.58 -0.34 1.76e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4700695 0.925 rs4700692 chr5:65396279 T/C cg21114390 chr5:65439923 SFRS12 -0.45 -5.99 -0.31 5.4e-9 Facial morphology (factor 19); LIHC cis rs4148883 0.689 rs2851275 chr4:100024883 A/G cg12011299 chr4:100065546 ADH4 0.36 7.27 0.37 2.53e-12 Alcohol dependence; LIHC cis rs1499614 1.000 rs1267818 chr7:66107024 C/T cg12463550 chr7:65579703 CRCP 0.67 6.93 0.35 2.1e-11 Gout; LIHC trans rs1552244 0.572 rs3774208 chr3:10164722 T/G cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs12744310 0.887 rs12046670 chr1:41809312 T/G cg03962019 chr1:41807865 NA 0.39 6.24 0.32 1.33e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.84 10.13 0.48 2.98e-21 Mean platelet volume; LIHC cis rs2859741 0.967 rs534131 chr1:37484237 T/C cg09363841 chr1:37513479 NA -0.18 -5.87 -0.3 1.05e-8 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs2235573 0.527 rs139885 chr22:38371039 C/T cg03989125 chr22:38214979 NA -0.44 -6.0 -0.31 4.9e-9 Glioblastoma;Glioma; LIHC cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg10360323 chr17:41437877 NA 0.4 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg23758822 chr17:41437982 NA 0.92 17.05 0.68 1.3e-47 Menopause (age at onset); LIHC cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.49 6.89 0.35 2.64e-11 Schizophrenia; LIHC cis rs7238033 0.624 rs17674709 chr18:43311380 C/G cg20610511 chr18:43302872 SLC14A1 0.38 6.34 0.32 7.44e-10 Bladder cancer; LIHC cis rs1003719 0.788 rs2835579 chr21:38457965 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.21 0.55 1.02e-28 Eye color traits; LIHC cis rs12220238 0.915 rs10824074 chr10:75876457 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.48 0.33 3.12e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1843834 0.898 rs2014887 chr2:225520082 A/G cg22455342 chr2:225449267 CUL3 0.43 6.09 0.31 3.08e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs6835098 1.000 rs10011724 chr4:174088865 A/G cg27433088 chr4:174089019 GALNT7 0.4 7.33 0.37 1.72e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg23172400 chr8:95962367 TP53INP1 -0.35 -7.83 -0.39 6.02e-14 Type 2 diabetes; LIHC cis rs595982 0.559 rs17206700 chr19:49361255 A/G cg21252483 chr19:49399788 TULP2 -0.8 -9.36 -0.45 1.1e-18 Red cell distribution width; LIHC cis rs1401999 1.000 rs1401999 chr3:183678342 C/G cg01324343 chr3:183735012 ABCC5 0.78 12.9 0.57 2.69e-31 Anterior chamber depth; LIHC cis rs3796352 0.667 rs34288509 chr3:52849493 G/C cg04865290 chr3:52927548 TMEM110 -0.45 -5.81 -0.3 1.44e-8 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2766692 1.000 rs4905941 chr14:100725438 A/G cg14866419 chr14:100704911 YY1 0.45 6.12 0.31 2.5e-9 Electroencephalographic traits in alcoholism; LIHC cis rs7959452 0.562 rs11177630 chr12:69767963 G/C cg22834771 chr12:69754056 YEATS4 -0.52 -9.17 -0.44 4.65e-18 Blood protein levels; LIHC cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg06634786 chr22:41940651 POLR3H -0.8 -8.58 -0.42 3.26e-16 Vitiligo; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg21606957 chr5:111753754 EPB41L4A 0.39 6.15 0.32 2.18e-9 Calcium levels; LIHC cis rs710216 0.536 rs710221 chr1:43414200 G/A cg03128534 chr1:43423976 SLC2A1 0.66 11.07 0.51 1.53e-24 Red cell distribution width; LIHC cis rs6430585 0.583 rs3087343 chr2:136622543 T/G cg07169764 chr2:136633963 MCM6 1.34 22.59 0.77 8.74e-70 Corneal structure; LIHC cis rs7772486 0.875 rs854146 chr6:146341033 A/G cg23711669 chr6:146136114 FBXO30 0.67 11.87 0.54 1.96e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs6570726 0.935 rs414222 chr6:145850482 C/T cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg16414030 chr3:133502952 NA -0.39 -6.01 -0.31 4.72e-9 Iron status biomarkers; LIHC cis rs12079745 0.590 rs12065030 chr1:169258201 A/G cg09363564 chr1:169337483 NME7;BLZF1 0.78 7.16 0.36 4.87e-12 QT interval; LIHC cis rs7208859 0.528 rs3764416 chr17:28900708 G/T cg13385521 chr17:29058706 SUZ12P -0.64 -6.01 -0.31 4.68e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4332037 0.851 rs73050128 chr7:1961882 C/A cg23422044 chr7:1970798 MAD1L1 -0.64 -7.33 -0.37 1.71e-12 Bipolar disorder; LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg21448741 chr8:58168803 NA 0.35 6.55 0.33 2.1e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16275967 chr1:161172255 NDUFS2 0.44 6.99 0.35 1.49e-11 Cognitive function; LIHC cis rs13266463 1.000 rs13266463 chr8:143403693 A/G cg16886403 chr8:143471632 TSNARE1 -0.44 -6.65 -0.34 1.16e-10 Schizophrenia; LIHC cis rs17685 0.712 rs60721456 chr7:75743820 T/A cg16684958 chr7:75615977 POR 0.41 6.73 0.34 7.13e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs736408 0.677 rs678 chr3:52820981 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.46 7.41 0.37 1.01e-12 Bipolar disorder; LIHC cis rs9549328 0.921 rs9549623 chr13:113640293 G/A cg14765414 chr13:113652335 MCF2L -0.31 -5.71 -0.3 2.42e-8 Systolic blood pressure; LIHC cis rs7872515 1.000 rs10992221 chr9:94832043 A/G cg01248375 chr9:94877805 SPTLC1 -0.53 -7.32 -0.37 1.78e-12 Bipolar disorder and schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06932451 chr19:36869880 NA 0.52 8.06 0.4 1.29e-14 Cognitive function; LIHC cis rs826838 1.000 rs1963562 chr12:38662896 C/T cg26384229 chr12:38710491 ALG10B 1.08 14.69 0.62 3.18e-38 Heart rate; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09326324 chr1:161123937 UFC1 0.43 6.71 0.34 8.01e-11 Cognitive function; LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg10755058 chr3:40428713 ENTPD3 -0.38 -6.39 -0.33 5.59e-10 Renal cell carcinoma; LIHC cis rs769267 0.965 rs2269873 chr19:19392401 T/C cg03709012 chr19:19516395 GATAD2A 0.94 15.73 0.65 2.5e-42 Tonsillectomy; LIHC cis rs372883 0.638 rs371432 chr21:30710876 G/A cg08807101 chr21:30365312 RNF160 -0.51 -5.95 -0.31 6.66e-9 Pancreatic cancer; LIHC cis rs34375054 0.660 rs12578446 chr12:125605887 A/G cg25124228 chr12:125621409 AACS -0.51 -9.13 -0.44 6.11e-18 Post bronchodilator FEV1/FVC ratio; LIHC cis rs9916302 0.660 rs4795379 chr17:37674683 T/G cg07936489 chr17:37558343 FBXL20 -0.84 -12.11 -0.55 2.45e-28 Glomerular filtration rate (creatinine); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06207460 chr9:4741011 AK3 -0.47 -6.44 -0.33 4e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6598955 0.670 rs3795685 chr1:26601385 A/G cg00852783 chr1:26633632 UBXN11 -0.52 -8.87 -0.43 4.27e-17 Obesity-related traits; LIHC cis rs2841277 0.708 rs10083496 chr14:105402786 G/A cg21017887 chr14:105400489 NA 0.66 12.76 0.57 9.24e-31 Rheumatoid arthritis; LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg12064134 chr16:90016061 DEF8 -0.45 -6.09 -0.31 2.98e-9 Skin colour saturation; LIHC cis rs208520 0.690 rs3846808 chr6:66818604 A/G cg07460842 chr6:66804631 NA -0.82 -9.18 -0.44 4.13e-18 Exhaled nitric oxide output; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20431080 chr7:149158239 ZNF777 0.44 6.44 0.33 4.08e-10 Cognitive function; LIHC trans rs11148252 0.553 rs2147692 chr13:53287023 C/G cg18335740 chr13:41363409 SLC25A15 0.56 10.18 0.48 1.95e-21 Lewy body disease; LIHC cis rs1577917 0.958 rs7382798 chr6:86559834 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.07 -0.4 1.22e-14 Response to antipsychotic treatment; LIHC trans rs11039798 0.764 rs12277213 chr11:48782176 G/A cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC trans rs1814175 0.630 rs1722019 chr11:49904102 G/A cg18944383 chr4:111397179 ENPEP 0.25 6.4 0.33 5.13e-10 Height; LIHC cis rs965469 0.779 rs6133031 chr20:3300857 A/C cg25506879 chr20:3388711 C20orf194 -0.5 -6.2 -0.32 1.66e-9 IFN-related cytopenia; LIHC cis rs9640161 0.830 rs3757425 chr7:150067640 A/C cg17279839 chr7:150038598 RARRES2 0.38 7.77 0.39 9.54e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7618501 0.633 rs12496973 chr3:50002245 T/C cg21467203 chr3:49911342 NA -0.46 -8.54 -0.42 4.46e-16 Intelligence (multi-trait analysis); LIHC cis rs9682041 0.696 rs13067560 chr3:170094190 G/A cg11886554 chr3:170076028 SKIL 0.63 5.82 0.3 1.35e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs344364 0.511 rs911391 chr16:1947016 C/A cg26897989 chr16:1907736 C16orf73 -0.47 -5.91 -0.3 8.18e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs208346 0.612 rs208356 chr7:2775825 A/T cg19717773 chr7:2847554 GNA12 0.5 9.58 0.46 1.99e-19 Loneliness (linear analysis); LIHC cis rs7209700 0.547 rs8078614 chr17:45351505 C/T cg08085267 chr17:45401833 C17orf57 0.52 6.75 0.34 6.41e-11 IgG glycosylation; LIHC trans rs7618501 1.000 rs2271961 chr3:49878113 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.79 -14.69 -0.62 3.16e-38 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs7548962 chr1:76139266 G/A cg10523679 chr1:76189770 ACADM 0.65 9.23 0.45 2.93e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11792861 0.926 rs72607163 chr9:111803128 G/T cg13535736 chr9:111863775 C9orf5 -0.42 -6.29 -0.32 9.53e-10 Menarche (age at onset); LIHC cis rs2599510 0.811 rs2710628 chr2:32758353 A/C cg02381751 chr2:32503542 YIPF4 0.51 7.07 0.36 8.97e-12 Interleukin-18 levels; LIHC cis rs1878931 0.520 rs2015640 chr16:3465018 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.69 -8.85 -0.43 4.79e-17 Body mass index (adult); LIHC cis rs9296092 0.538 rs9461887 chr6:33526827 C/T cg13560919 chr6:33536144 NA -0.39 -6.41 -0.33 4.74e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs6701037 0.625 rs67332874 chr1:175128537 G/A cg17845761 chr1:175162550 KIAA0040 -0.43 -7.19 -0.36 4.16e-12 Alcohol dependence; LIHC cis rs7843479 0.524 rs1031884 chr8:21788984 C/T cg17168535 chr8:21777572 XPO7 0.62 11.24 0.52 3.86e-25 Mean corpuscular volume; LIHC cis rs807669 0.807 rs807431 chr22:19242361 G/A cg02655711 chr22:19163373 SLC25A1 0.39 7.39 0.37 1.13e-12 Metabolite levels; LIHC cis rs58688157 0.880 rs12272314 chr11:590648 A/G cg16486109 chr11:613632 IRF7 0.6 6.82 0.35 4.15e-11 Systemic lupus erythematosus; LIHC cis rs2204008 0.522 rs12370263 chr12:38113311 A/G cg26384229 chr12:38710491 ALG10B 0.77 9.36 0.45 1.11e-18 Bladder cancer; LIHC cis rs742115 0.563 rs7762842 chr6:11303695 G/A cg25250968 chr6:11318770 NEDD9 -0.4 -6.19 -0.32 1.69e-9 Coronary artery disease; LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs7927771 0.524 rs10742824 chr11:47864842 C/T cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC cis rs67311347 0.668 rs73071710 chr3:40288587 A/G cg00656387 chr3:40428638 ENTPD3 0.45 7.27 0.37 2.44e-12 Renal cell carcinoma; LIHC cis rs763121 0.888 rs2235229 chr22:39124912 A/G cg06022373 chr22:39101656 GTPBP1 0.63 12.15 0.55 1.73e-28 Menopause (age at onset); LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.72 10.72 0.5 2.66e-23 Lymphocyte counts; LIHC trans rs1814175 0.791 rs9787917 chr11:49937281 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs748404 0.697 rs473016 chr15:43558823 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.8 0.35 4.71e-11 Lung cancer; LIHC cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg18306943 chr3:40428807 ENTPD3 0.35 5.97 0.31 6.03e-9 Renal cell carcinoma; LIHC trans rs4073416 0.712 rs4899179 chr14:65926748 A/C cg00158227 chr1:6514781 ESPN -0.27 -6.04 -0.31 3.99e-9 N-glycan levels; LIHC cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg17971929 chr21:40555470 PSMG1 0.81 9.67 0.46 1.06e-19 Cognitive function; LIHC cis rs600806 0.850 rs10858091 chr1:109935578 T/C cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.555 rs10880611 chr12:38509316 C/G cg13010199 chr12:38710504 ALG10B 0.46 6.22 0.32 1.42e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg05564831 chr3:52568323 NT5DC2 0.36 5.78 0.3 1.68e-8 Bipolar disorder; LIHC cis rs763121 0.925 rs5757251 chr22:39100128 G/A cg06022373 chr22:39101656 GTPBP1 0.64 12.07 0.55 3.41e-28 Menopause (age at onset); LIHC cis rs8044995 0.563 rs3785116 chr16:68372730 G/A cg03983715 chr16:68378420 PRMT7 -0.5 -5.71 -0.3 2.45e-8 Schizophrenia; LIHC cis rs7772486 0.902 rs2748500 chr6:146314852 C/A cg23711669 chr6:146136114 FBXO30 0.55 9.75 0.47 5.52e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7312933 0.526 rs1669892 chr12:42811305 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.23 -0.41 4.02e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6547741 0.935 rs2384626 chr2:27773648 A/G cg27432699 chr2:27873401 GPN1 0.69 11.34 0.52 1.65e-25 Oral cavity cancer; LIHC cis rs896854 0.548 rs574183 chr8:95973816 A/G cg16049864 chr8:95962084 TP53INP1 0.6 9.39 0.45 8.68e-19 Type 2 diabetes; LIHC cis rs2073300 0.609 rs17830281 chr20:23350525 C/T cg16736954 chr20:23401023 NAPB 0.73 8.71 0.43 1.31e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs965469 0.947 rs4611719 chr20:3228423 G/A cg25506879 chr20:3388711 C20orf194 -0.59 -6.8 -0.35 4.69e-11 IFN-related cytopenia; LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.85 0.57 4.09e-31 Prudent dietary pattern; LIHC cis rs8067545 0.563 rs3850780 chr17:20181902 A/C cg13482628 chr17:19912719 NA -0.41 -6.72 -0.34 7.79e-11 Schizophrenia; LIHC cis rs13088645 0.729 rs7620040 chr3:134163082 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.36 -6.66 -0.34 1.09e-10 Coronary artery disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19909334 chr14:53418212 FERMT2 -0.44 -6.47 -0.33 3.33e-10 Cognitive function; LIHC cis rs7639513 0.767 rs9878151 chr3:12703714 G/C cg23032965 chr3:12705835 RAF1 0.65 7.83 0.39 6.22e-14 Itch intensity from mosquito bite; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg23131131 chr22:24373011 LOC391322 -0.56 -7.71 -0.38 1.38e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs748404 0.631 rs2412781 chr15:43667900 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.53 -8.46 -0.42 7.84e-16 Lung cancer; LIHC cis rs10744422 1.000 rs7309225 chr12:123288439 A/G cg18912006 chr12:123335444 HIP1R -0.63 -7.25 -0.36 2.86e-12 Schizophrenia; LIHC cis rs9303401 0.659 rs17822837 chr17:56737838 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 9.05 0.44 1.1e-17 Cognitive test performance; LIHC cis rs10916814 0.632 rs12089623 chr1:20903643 G/A cg24502330 chr1:20914028 CDA -0.31 -6.87 -0.35 3.04e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs12477438 0.520 rs11123765 chr2:99768064 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC trans rs4650994 0.544 rs11579513 chr1:178496092 T/C cg05059571 chr16:84539110 KIAA1609 -0.41 -7.04 -0.36 1.03e-11 HDL cholesterol levels;HDL cholesterol; LIHC cis rs79057730 0.527 rs34519158 chr7:811114 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.8 8.9 0.43 3.33e-17 Initial pursuit acceleration; LIHC cis rs7917772 0.536 rs12357172 chr10:104388549 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.75 8.57 0.42 3.55e-16 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1904096 0.506 rs2865350 chr4:95212813 A/T cg11021082 chr4:95130006 SMARCAD1 0.45 7.49 0.38 6.07e-13 Type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13294780 chr4:140005756 ELF2 -0.44 -6.12 -0.31 2.58e-9 Pancreatic cancer; LIHC cis rs13108904 0.901 rs7695691 chr4:1304632 A/G cg05025164 chr4:1340916 KIAA1530 0.55 8.64 0.42 2.18e-16 Obesity-related traits; LIHC cis rs6582630 0.502 rs3902522 chr12:38271203 T/C cg13010199 chr12:38710504 ALG10B 0.48 5.8 0.3 1.47e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs7776786 0.934 rs17349342 chr7:18815473 A/C cg13420273 chr7:18810212 HDAC9 0.26 6.02 0.31 4.51e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9733 0.519 rs6700022 chr1:150670484 G/T cg15448220 chr1:150897856 SETDB1 -0.4 -6.36 -0.33 6.55e-10 Tonsillectomy; LIHC cis rs7772486 0.875 rs9399573 chr6:146403255 A/T cg23711669 chr6:146136114 FBXO30 0.58 10.08 0.48 4.26e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs7714584 1.000 rs11167519 chr5:150265407 C/T cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC trans rs2243480 0.614 rs34032527 chr7:65565141 C/G cg10756647 chr7:56101905 PSPH 1.06 13.28 0.58 9.29e-33 Diabetic kidney disease; LIHC cis rs4332037 0.722 rs4719331 chr7:1914679 A/C cg23422044 chr7:1970798 MAD1L1 -0.69 -10.6 -0.5 6.77e-23 Bipolar disorder; LIHC cis rs11212737 0.694 rs2624134 chr11:108513335 C/T cg22776369 chr11:108536276 DDX10 0.37 6.21 0.32 1.53e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs5760092 0.572 rs738806 chr22:24234172 A/G cg12419862 chr22:24373484 LOC391322 -0.49 -5.91 -0.3 8.15e-9 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs67981189 0.593 rs6573994 chr14:71536662 G/A cg15816911 chr14:71606274 NA 0.43 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs9916302 0.821 rs412430 chr17:37737094 C/G cg00129232 chr17:37814104 STARD3 -0.4 -6.39 -0.33 5.36e-10 Glomerular filtration rate (creatinine); LIHC cis rs4499344 0.657 rs259238 chr19:33140381 A/G cg22980127 chr19:33182716 NUDT19 -0.52 -6.49 -0.33 3.07e-10 Mean platelet volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04516253 chr19:40596853 ZNF780A -0.44 -6.31 -0.32 8.81e-10 Pancreatic cancer; LIHC trans rs6968419 0.802 rs6978849 chr7:115809732 A/C cg25721452 chr12:102133339 SYCP3 -0.39 -6.16 -0.32 2.1e-9 Intraocular pressure; LIHC cis rs11098499 0.908 rs2017057 chr4:120257711 A/G cg09307838 chr4:120376055 NA 0.74 11.27 0.52 2.82e-25 Corneal astigmatism; LIHC trans rs11098499 0.615 rs28850368 chr4:120554313 G/A cg25214090 chr10:38739885 LOC399744 0.5 8.08 0.4 1.12e-14 Corneal astigmatism; LIHC cis rs78456975 0.739 rs72776248 chr2:1521314 A/G cg01028140 chr2:1542097 TPO -0.5 -5.72 -0.3 2.34e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1552244 0.882 rs3846168 chr3:9996925 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.86 0.51 8.13e-24 Alzheimer's disease; LIHC cis rs7412746 0.611 rs11803940 chr1:150685835 A/G cg13175981 chr1:150552382 MCL1 -0.42 -5.74 -0.3 2.12e-8 Melanoma; LIHC cis rs240764 0.746 rs151572 chr6:101110984 C/T cg09795085 chr6:101329169 ASCC3 0.52 7.4 0.37 1.06e-12 Neuroticism; LIHC cis rs6456156 0.586 rs12213801 chr6:167474084 T/A cg23791538 chr6:167370224 RNASET2 -0.61 -10.39 -0.49 3.77e-22 Primary biliary cholangitis; LIHC cis rs7927771 0.524 rs7936948 chr11:47704200 T/G cg20307385 chr11:47447363 PSMC3 0.77 11.58 0.53 2.15e-26 Subjective well-being; LIHC cis rs1943345 1.000 rs1943345 chr11:82876270 G/T cg07047830 chr11:82868014 PCF11 -0.43 -6.87 -0.35 3e-11 Obesity-related traits; LIHC cis rs1552244 0.510 rs13075308 chr3:10034925 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg08280861 chr8:58055591 NA 0.54 6.21 0.32 1.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs9406162 chr6:8466196 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs2439831 1.000 rs101094 chr15:43787322 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.64 9.01 0.44 1.47e-17 Lung cancer in ever smokers; LIHC cis rs11030122 0.702 rs17279635 chr11:3973083 A/C cg18678763 chr11:4115507 RRM1 0.57 8.37 0.41 1.45e-15 Mean platelet volume;Platelet distribution width; LIHC trans rs13113518 0.756 rs11939652 chr4:56398709 T/A cg15358633 chr12:38710606 ALG10B 0.43 6.1 0.31 2.91e-9 Height; LIHC cis rs921968 0.573 rs684776 chr2:219324016 T/C cg02176678 chr2:219576539 TTLL4 0.55 7.72 0.39 1.27e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs2836950 0.509 rs11088466 chr21:40580017 T/A cg11890956 chr21:40555474 PSMG1 -0.47 -7.77 -0.39 9.52e-14 Menarche (age at onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01377139 chr6:41039751 C6orf130;NFYA -0.41 -6.09 -0.31 3e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6088590 0.965 rs6088620 chr20:33412022 A/G cg06115741 chr20:33292138 TP53INP2 0.58 8.02 0.4 1.72e-14 Coronary artery disease; LIHC cis rs12908161 1.000 rs4643294 chr15:85250253 C/T cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC cis rs9902453 0.765 rs2729448 chr17:28091953 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -13.49 -0.59 1.51e-33 Coffee consumption (cups per day); LIHC cis rs66569888 0.516 rs11681404 chr2:106736313 T/C cg16099169 chr2:106886729 NA -0.49 -5.8 -0.3 1.51e-8 Facial morphology (factor 23); LIHC cis rs4699052 0.963 rs6533078 chr4:104212156 C/T cg16532752 chr4:104119610 CENPE -0.39 -6.29 -0.32 9.82e-10 Testicular germ cell tumor; LIHC cis rs2204008 0.837 rs11495722 chr12:38337245 G/A cg26384229 chr12:38710491 ALG10B 0.87 10.79 0.5 1.54e-23 Bladder cancer; LIHC cis rs68170813 0.570 rs7794915 chr7:106849393 C/T cg02696742 chr7:106810147 HBP1 -0.53 -5.81 -0.3 1.42e-8 Coronary artery disease; LIHC cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 9.27 0.45 2.09e-18 Platelet count; LIHC cis rs66573146 0.656 rs111560662 chr4:6952766 C/T cg15105060 chr4:7024189 TBC1D14 -0.77 -6.38 -0.33 5.87e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9486719 0.843 rs2499792 chr6:96846264 A/C cg06623918 chr6:96969491 KIAA0776 0.69 6.69 0.34 8.95e-11 Migraine;Coronary artery disease; LIHC cis rs9783347 1.000 rs4353250 chr11:18323517 T/C cg15585147 chr11:18324498 HPS5 0.45 6.94 0.35 2.02e-11 Pancreatic cancer; LIHC cis rs7107174 1.000 rs10793303 chr11:78060750 G/A cg02023728 chr11:77925099 USP35 0.47 8.87 0.43 4.25e-17 Testicular germ cell tumor; LIHC cis rs2075165 0.901 rs10908492 chr1:156224795 C/T cg07234388 chr1:156261841 TMEM79 0.49 8.57 0.42 3.66e-16 Tonsillectomy; LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.59 8.45 0.42 8.3e-16 Lymphocyte counts; LIHC cis rs6430585 0.528 rs309154 chr2:136726567 C/T cg07169764 chr2:136633963 MCM6 1.29 21.25 0.75 1.82e-64 Corneal structure; LIHC cis rs6594499 0.500 rs12514810 chr5:110455357 T/A cg04022379 chr5:110408740 TSLP 0.57 9.24 0.45 2.72e-18 Allergic disease (asthma, hay fever or eczema); LIHC cis rs57221529 0.766 rs28563961 chr5:554498 C/G cg09021430 chr5:549028 NA -0.44 -8.74 -0.43 1.1e-16 Lung disease severity in cystic fibrosis; LIHC cis rs1008375 1.000 rs2872958 chr4:17665032 A/G cg16339924 chr4:17578868 LAP3 0.41 5.97 0.31 5.95e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg22903471 chr2:27725779 GCKR -0.48 -8.34 -0.41 1.91e-15 Total body bone mineral density; LIHC cis rs4474465 0.920 rs4474466 chr11:78204406 C/T cg27205649 chr11:78285834 NARS2 0.38 5.71 0.3 2.4e-8 Alzheimer's disease (survival time); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00995209 chr8:144881704 SCRIB -0.43 -6.66 -0.34 1.07e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3749237 0.595 rs11130192 chr3:49467206 C/G cg02487422 chr3:49467188 NICN1 0.42 6.55 0.33 2.16e-10 Resting heart rate; LIHC cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.8e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg19591588 chr3:45730799 SACM1L -0.37 -6.18 -0.32 1.83e-9 Immature fraction of reticulocytes; LIHC cis rs7116495 1.000 rs6592448 chr11:71670044 C/T cg26138937 chr11:71823887 C11orf51 0.81 8.05 0.4 1.41e-14 Severe influenza A (H1N1) infection; LIHC cis rs12477438 0.798 rs1580068 chr2:99649969 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.84 -0.65 9.44e-43 Chronic sinus infection; LIHC cis rs1419980 0.673 rs10845432 chr12:7728131 T/C cg14906510 chr12:7781169 NA 0.47 7.23 0.36 3.18e-12 HDL cholesterol levels; LIHC cis rs6752107 0.967 rs11680130 chr2:234157258 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.13 0.4 7.94e-15 Crohn's disease;Inflammatory bowel disease; LIHC trans rs17685 0.712 rs10271413 chr7:75754858 G/A cg19862616 chr7:65841803 NCRNA00174 0.91 18.38 0.7 5.97e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7100689 0.556 rs6585971 chr10:82145057 G/C cg00277334 chr10:82204260 NA -0.58 -7.53 -0.38 4.6e-13 Post bronchodilator FEV1; LIHC cis rs8067354 0.609 rs1292066 chr17:57932314 T/A cg13753209 chr17:57696993 CLTC 0.69 10.45 0.49 2.29e-22 Hemoglobin concentration; LIHC cis rs748404 0.578 rs510108 chr15:43605439 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.96 0.44 2.06e-17 Lung cancer; LIHC cis rs950169 0.840 rs2896002 chr15:84945121 A/G cg03959625 chr15:84868606 LOC388152 0.47 6.76 0.34 6.14e-11 Schizophrenia; LIHC cis rs1577917 0.610 rs11752795 chr6:86287129 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.34 6.11 0.31 2.7e-9 Response to antipsychotic treatment; LIHC cis rs9543976 1.000 rs2328964 chr13:76138830 G/T cg01531495 chr13:76123901 UCHL3 0.52 6.12 0.31 2.54e-9 Diabetic retinopathy; LIHC cis rs9858542 0.953 rs9818590 chr3:49525096 A/G cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs12286929 0.576 rs2275997 chr11:115100186 A/G cg04055981 chr11:115044050 NA 0.36 5.76 0.3 1.9e-8 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1008375 1.000 rs11724495 chr4:17621310 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.76 0.3 1.89e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs908922 0.523 rs4845786 chr1:152510144 A/G cg20991723 chr1:152506922 NA 0.5 8.59 0.42 3.19e-16 Hair morphology; LIHC cis rs7412746 0.524 rs58304714 chr1:150831561 T/A cg18016565 chr1:150552671 MCL1 0.56 10.25 0.48 1.14e-21 Melanoma; LIHC cis rs72627509 0.951 rs17087335 chr4:57838583 G/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.6 -8.83 -0.43 5.59e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg06453172 chr10:134556979 INPP5A -0.64 -8.35 -0.41 1.72e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs34779708 0.966 rs4934735 chr10:35496730 C/T cg03585969 chr10:35415529 CREM -0.85 -13.01 -0.58 1.04e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4665809 1.000 rs6704930 chr2:26325705 G/A cg27170947 chr2:26402098 FAM59B -0.65 -8.22 -0.41 4.22e-15 Gut microbiome composition (summer); LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg23978390 chr7:1156363 C7orf50 0.56 8.85 0.43 4.77e-17 Longevity;Endometriosis; LIHC cis rs6502050 0.835 rs3924780 chr17:80112978 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC trans rs875971 0.545 rs67775320 chr7:65658779 T/C cg26939375 chr7:64535504 NA 0.4 6.37 0.33 6.17e-10 Aortic root size; LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.22 -0.32 1.49e-9 Diastolic blood pressure; LIHC cis rs7429990 0.932 rs936428 chr3:48167281 A/G cg11946769 chr3:48343235 NME6 -0.48 -6.41 -0.33 4.78e-10 Educational attainment (years of education); LIHC cis rs1008375 1.000 rs4698200 chr4:17657051 G/A cg04450456 chr4:17643702 FAM184B 0.34 5.8 0.3 1.53e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs12478296 1.000 rs11899408 chr2:243014630 A/G cg01596870 chr19:55963115 NA -0.63 -7.97 -0.4 2.4e-14 Obesity-related traits; LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg06656553 chr16:89960601 TCF25 -0.46 -5.91 -0.3 8.17e-9 Skin colour saturation; LIHC cis rs2760061 0.598 rs632832 chr1:228121838 G/T cg02753203 chr1:228287806 NA -0.49 -7.85 -0.39 5.52e-14 Diastolic blood pressure; LIHC trans rs7937682 0.961 rs4935790 chr11:111633014 T/C cg18187862 chr3:45730750 SACM1L -0.56 -6.42 -0.33 4.64e-10 Primary sclerosing cholangitis; LIHC cis rs9549367 0.789 rs9549716 chr13:113908478 G/A cg00898013 chr13:113819073 PROZ -0.34 -6.21 -0.32 1.5e-9 Platelet distribution width; LIHC cis rs894734 0.567 rs7138907 chr12:54324576 C/T cg12374095 chr12:54320830 NA 0.44 6.81 0.35 4.38e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs7131987 0.650 rs11050208 chr12:29510369 T/G cg14222432 chr12:29376421 FAR2 0.34 6.19 0.32 1.68e-9 QT interval; LIHC cis rs2455799 0.634 rs62243670 chr3:15918990 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.49 -0.38 6.1e-13 Mean platelet volume; LIHC trans rs11098499 0.863 rs3775848 chr4:120447724 C/T cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs807029 0.577 rs701834 chr10:102761801 C/T cg25179470 chr10:102756915 LZTS2 0.44 6.04 0.31 4.05e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs5756813 0.688 rs56114444 chr22:38123364 C/T cg19894588 chr14:64061835 NA -0.6 -7.73 -0.39 1.2e-13 Optic cup area;Vertical cup-disc ratio; LIHC trans rs16863064 0.932 rs9817667 chr3:187887694 A/G cg02569115 chr17:76922138 TIMP2 -0.36 -6.22 -0.32 1.41e-9 Schizophrenia; LIHC cis rs12586317 0.620 rs58320987 chr14:35587726 T/C cg16230307 chr14:35515116 FAM177A1 0.78 12.93 0.57 2.07e-31 Psoriasis; LIHC cis rs796364 0.806 rs76568708 chr2:200929531 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.78 -8.73 -0.43 1.15e-16 Schizophrenia; LIHC cis rs13118159 0.651 rs4974599 chr4:1314430 A/C cg05025164 chr4:1340916 KIAA1530 0.61 9.19 0.45 3.82e-18 Longevity; LIHC cis rs13108904 0.936 rs4974540 chr4:1213463 C/T cg20887711 chr4:1340912 KIAA1530 0.45 6.3 0.32 8.98e-10 Obesity-related traits; LIHC cis rs250677 0.641 rs2915807 chr5:148450950 A/G cg18129178 chr5:148520854 ABLIM3 -0.53 -6.85 -0.35 3.36e-11 Breast cancer; LIHC cis rs10791097 0.694 rs10791103 chr11:130757161 G/A cg22079354 chr11:130786696 SNX19 0.42 5.96 0.31 6.25e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11608355 0.545 rs11066737 chr12:109904792 A/G cg05360138 chr12:110035743 NA -0.96 -11.1 -0.51 1.14e-24 Neuroticism; LIHC cis rs17376456 0.825 rs28412976 chr5:93248377 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs713477 1.000 rs4901562 chr14:55901373 G/A cg13175173 chr14:55914753 NA -0.31 -6.94 -0.35 2.01e-11 Pediatric bone mineral content (femoral neck); LIHC trans rs7899916 1.000 rs7899916 chr10:4786841 C/T cg19819135 chr1:70710422 SFRS11 0.37 6.6 0.34 1.57e-10 Major depressive disorder; LIHC cis rs4700695 0.925 rs12518262 chr5:65414004 A/G cg21114390 chr5:65439923 SFRS12 -0.47 -6.18 -0.32 1.83e-9 Facial morphology (factor 19); LIHC cis rs10503871 0.604 rs12548308 chr8:30446493 G/A cg26383811 chr8:30366931 RBPMS 0.4 6.17 0.32 1.89e-9 Metabolite levels (X-11787); LIHC trans rs3749237 0.964 rs11714957 chr3:49776178 C/T cg21659725 chr3:3221576 CRBN 0.78 12.34 0.56 3.41e-29 Resting heart rate; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06796825 chr17:17140633 FLCN 0.45 6.18 0.32 1.85e-9 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg07424592 chr7:64974309 NA 0.82 9.64 0.46 1.27e-19 Diabetic kidney disease; LIHC cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg24879335 chr3:133465180 TF 0.29 6.48 0.33 3.12e-10 Iron status biomarkers; LIHC cis rs2842992 0.789 rs9365093 chr6:160175819 C/G cg11366901 chr6:160182831 ACAT2 0.94 15.99 0.65 2.37e-43 Age-related macular degeneration (geographic atrophy); LIHC trans rs12478296 0.685 rs35577962 chr2:242993575 A/G cg01596870 chr19:55963115 NA -0.65 -9.31 -0.45 1.54e-18 Obesity-related traits; LIHC cis rs6754311 0.731 rs12988076 chr2:136569848 C/A cg25344623 chr2:136566232 LCT 0.42 8.59 0.42 3.04e-16 Mosquito bite size; LIHC cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg13393036 chr8:95962371 TP53INP1 0.38 8.89 0.43 3.7e-17 Type 2 diabetes; LIHC cis rs6061231 0.837 rs6121558 chr20:60961365 A/G cg22601191 chr20:60968625 CABLES2 0.43 5.75 0.3 2.03e-8 Colorectal cancer; LIHC cis rs780094 0.585 rs7586601 chr2:27584666 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.39 -5.78 -0.3 1.66e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs7572733 0.534 rs4850815 chr2:198786167 G/T cg00792783 chr2:198669748 PLCL1 -0.46 -6.79 -0.34 5.11e-11 Dermatomyositis; LIHC cis rs7223966 1.000 rs9891018 chr17:61827856 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.87 0.35 2.95e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs250677 0.958 rs36078 chr5:148430567 G/A cg18129178 chr5:148520854 ABLIM3 -0.48 -6.5 -0.33 2.87e-10 Breast cancer; LIHC cis rs7258465 1.000 rs34010330 chr19:18559657 G/C cg10790698 chr19:18539756 SSBP4 -0.37 -7.7 -0.38 1.52e-13 Breast cancer; LIHC trans rs2739330 0.828 rs5760099 chr22:24248414 G/A cg06437703 chr8:37914619 EIF4EBP1 -0.48 -7.08 -0.36 8.06e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9486715 0.867 rs3860243 chr6:96905303 T/G cg06623918 chr6:96969491 KIAA0776 0.83 14.52 0.62 1.57e-37 Headache; LIHC cis rs12477438 0.735 rs12474477 chr2:99690408 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.91 -0.54 1.38e-27 Chronic sinus infection; LIHC trans rs17685 0.712 rs1639620 chr7:75704090 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2842992 0.830 rs2025190 chr6:160138241 C/T cg11366901 chr6:160182831 ACAT2 0.96 16.38 0.66 6.31e-45 Age-related macular degeneration (geographic atrophy); LIHC cis rs34172651 0.517 rs12927710 chr16:24790282 A/C cg00152838 chr16:24741724 TNRC6A -0.49 -5.78 -0.3 1.7e-8 Intelligence (multi-trait analysis); LIHC cis rs12474201 0.928 rs12998762 chr2:46938393 A/C cg06386533 chr2:46925753 SOCS5 0.75 8.18 0.4 5.53e-15 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23182539 chr10:121355708 TIAL1 0.48 7.02 0.35 1.21e-11 Pancreatic cancer; LIHC cis rs17685 0.753 rs10251863 chr7:75790192 T/C cg04592579 chr7:75616294 TMEM120A 0.41 7.01 0.35 1.28e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2806561 1.000 rs2776819 chr1:23470116 A/T cg19743168 chr1:23544995 NA 0.4 7.31 0.37 1.89e-12 Height; LIHC cis rs7647973 0.710 rs1532204 chr3:49609477 C/G cg03060546 chr3:49711283 APEH 0.62 6.96 0.35 1.76e-11 Menarche (age at onset); LIHC cis rs6456156 0.742 rs1331299 chr6:167533467 A/G cg23791538 chr6:167370224 RNASET2 -0.36 -5.77 -0.3 1.77e-8 Primary biliary cholangitis; LIHC cis rs2832191 0.791 rs2251517 chr21:30531951 T/G cg24692254 chr21:30365293 RNF160 0.72 12.2 0.55 1.15e-28 Dental caries; LIHC cis rs17102423 0.788 rs11158575 chr14:65581665 T/C cg11161011 chr14:65562177 MAX -0.51 -6.94 -0.35 1.93e-11 Obesity-related traits; LIHC cis rs240764 0.817 rs240146 chr6:101078718 G/A cg09795085 chr6:101329169 ASCC3 0.53 7.45 0.37 7.93e-13 Neuroticism; LIHC cis rs2292096 1.000 rs6658596 chr1:200748921 A/G cg11814564 chr1:200748674 CAMSAP1L1 0.47 6.29 0.32 9.76e-10 Epilepsy; LIHC cis rs240764 0.717 rs180963 chr6:101127213 T/C cg12253828 chr6:101329408 ASCC3 0.42 6.41 0.33 4.94e-10 Neuroticism; LIHC cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg11890956 chr21:40555474 PSMG1 -1.02 -14.18 -0.61 3.13e-36 Cognitive function; LIHC cis rs2066819 1.000 rs1802236 chr12:56679751 A/G cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs9378688 1.000 rs72830184 chr6:2223930 T/C cg12303981 chr6:2244766 GMDS -0.49 -6.22 -0.32 1.48e-9 Caudate nucleus volume; LIHC cis rs875971 0.830 rs7799834 chr7:65880694 A/C cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs7945705 0.747 rs10840158 chr11:9020897 A/C cg12365402 chr11:9010492 NRIP3 -0.34 -8.94 -0.44 2.54e-17 Hemoglobin concentration; LIHC trans rs10411161 0.702 rs6509592 chr19:52393150 G/A cg22319618 chr22:45562946 NUP50 -0.63 -8.51 -0.42 5.59e-16 Breast cancer; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs1018836 0.892 rs10103198 chr8:91579436 A/T cg16814680 chr8:91681699 NA -0.47 -7.57 -0.38 3.58e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs875971 0.862 rs778680 chr7:65840414 G/A cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs9399135 0.967 rs4142299 chr6:135377186 G/T cg22676075 chr6:135203613 NA 0.42 6.67 0.34 1.02e-10 Red blood cell count; LIHC cis rs13108904 0.560 rs11247994 chr4:1343720 G/A cg13395646 chr4:1353034 KIAA1530 -0.85 -12.92 -0.57 2.19e-31 Obesity-related traits; LIHC cis rs778371 0.697 rs6717048 chr2:233586427 T/C cg08000102 chr2:233561755 GIGYF2 0.89 14.78 0.62 1.46e-38 Schizophrenia; LIHC cis rs10876993 0.826 rs1678534 chr12:58057435 A/C cg15848620 chr12:58087721 OS9 -0.54 -7.31 -0.37 1.91e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs2832191 0.729 rs2832201 chr21:30499841 A/G cg08807101 chr21:30365312 RNF160 -0.74 -10.71 -0.5 2.87e-23 Dental caries; LIHC cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg03806693 chr22:41940476 POLR3H -1.14 -13.48 -0.59 1.66e-33 Vitiligo; LIHC cis rs25645 0.502 rs8065126 chr17:38099035 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.49 7.36 0.37 1.42e-12 Myeloid white cell count; LIHC cis rs1046896 0.731 rs9906115 chr17:80791469 G/A cg22027946 chr17:80790580 TBCD;ZNF750 0.52 7.43 0.37 8.98e-13 Glycated hemoglobin levels; LIHC cis rs7674212 0.570 rs12501621 chr4:104095505 T/G cg16532752 chr4:104119610 CENPE -0.45 -6.99 -0.35 1.41e-11 Type 2 diabetes; LIHC cis rs826838 1.000 rs1684395 chr12:39083161 T/G cg26384229 chr12:38710491 ALG10B -0.56 -8.63 -0.42 2.31e-16 Heart rate; LIHC cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.16 -0.36 5e-12 Diabetic kidney disease; LIHC cis rs9322817 0.691 rs4946648 chr6:105329422 G/T cg02098413 chr6:105308735 HACE1 0.41 7.7 0.38 1.49e-13 Thyroid stimulating hormone; LIHC cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg17554472 chr22:41940697 POLR3H -0.57 -6.18 -0.32 1.78e-9 Vitiligo; LIHC cis rs1982346 1.000 rs2544426 chr4:106717797 C/T cg24545054 chr4:106630052 GSTCD;INTS12 0.59 5.91 0.3 8.34e-9 Lung function (FEV1); LIHC cis rs2153535 0.580 rs2225765 chr6:8481785 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs8072100 0.745 rs7214410 chr17:45422628 A/G cg25173405 chr17:45401733 C17orf57 -0.44 -6.07 -0.31 3.38e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs13223928 0.538 rs10951042 chr7:3139417 T/C cg19214707 chr7:3157722 NA -0.41 -7.76 -0.39 9.77e-14 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs919433 0.653 rs700651 chr2:198631714 G/A cg10820045 chr2:198174542 NA 0.49 7.44 0.37 8.27e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6920965 0.602 rs10872302 chr6:126180631 G/T cg05901451 chr6:126070800 HEY2 -0.37 -6.24 -0.32 1.29e-9 High light scatter reticulocyte count; LIHC cis rs523522 0.962 rs55848094 chr12:120966659 G/A cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs2354432 0.556 rs2353975 chr1:146837703 C/A cg25205988 chr1:146714368 CHD1L 0.84 9.54 0.46 2.78e-19 Mitochondrial DNA levels; LIHC cis rs801193 0.569 rs10950050 chr7:66239588 A/C cg18252515 chr7:66147081 NA -0.44 -6.51 -0.33 2.71e-10 Aortic root size; LIHC cis rs1008375 0.966 rs3775927 chr4:17599894 G/T cg16339924 chr4:17578868 LAP3 0.46 6.28 0.32 1.01e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg23758822 chr17:41437982 NA 0.91 16.84 0.67 8.86e-47 Menopause (age at onset); LIHC cis rs6089829 0.962 rs6062777 chr20:61663748 G/A cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.66e-17 Prudent dietary pattern; LIHC cis rs1190552 0.846 rs1061924 chr14:102975655 C/T cg10241871 chr14:102965420 TECPR2 -0.46 -6.99 -0.35 1.45e-11 Blood protein levels; LIHC cis rs703842 1.000 rs11172342 chr12:58187758 G/T cg18357645 chr12:58087776 OS9 -0.45 -6.98 -0.35 1.49e-11 Multiple sclerosis; LIHC cis rs12497850 0.931 rs9876848 chr3:48844059 G/A cg20833759 chr3:49053208 WDR6;DALRD3 0.39 5.73 0.3 2.26e-8 Parkinson's disease; LIHC cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg09417038 chr21:47716443 C21orf57 -0.5 -7.41 -0.37 9.98e-13 Testicular germ cell tumor; LIHC cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg08392591 chr16:89556376 ANKRD11 0.55 8.8 0.43 7.07e-17 Multiple myeloma (IgH translocation); LIHC cis rs2336384 1.000 rs2103876 chr1:12053100 C/T cg13216073 chr1:12042593 MFN2 0.43 6.53 0.33 2.39e-10 Platelet count; LIHC cis rs10508774 1.000 rs116546771 chr10:32884600 C/T cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs5756813 0.661 rs2246503 chr22:38204540 C/A cg19894588 chr14:64061835 NA -0.68 -10.13 -0.48 2.97e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs6546550 0.935 rs6546551 chr2:70073703 C/T cg02498382 chr2:70120550 SNRNP27 -0.39 -6.35 -0.32 6.76e-10 Prevalent atrial fibrillation; LIHC cis rs138880 0.542 rs9616393 chr22:50314809 A/G cg02269571 chr22:50332266 NA 0.95 10.08 0.48 4.25e-21 Schizophrenia; LIHC cis rs763121 0.962 rs1980455 chr22:38925719 A/C cg14440974 chr22:39074834 NA -0.34 -5.77 -0.3 1.8e-8 Menopause (age at onset); LIHC cis rs9649213 0.593 rs7778015 chr7:97920270 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.81 -0.3 1.43e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg27572855 chr1:25598939 RHD 0.4 8.72 0.43 1.26e-16 Erythrocyte sedimentation rate; LIHC cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs679087 1.000 rs302321 chr12:29928388 A/C cg14258853 chr12:29935411 TMTC1 0.5 8.04 0.4 1.51e-14 Schizophrenia; LIHC cis rs2404602 0.622 rs11632365 chr15:77139080 G/A cg03037974 chr15:76606532 NA -0.51 -7.94 -0.39 2.93e-14 Blood metabolite levels; LIHC cis rs9486715 0.838 rs6928442 chr6:96870118 A/G cg06623918 chr6:96969491 KIAA0776 0.85 14.89 0.63 5.33e-39 Headache; LIHC cis rs2066819 1.000 rs11575231 chr12:56744445 T/C cg26714650 chr12:56694279 CS -1.35 -12.74 -0.57 1.09e-30 Psoriasis vulgaris; LIHC cis rs4974559 0.895 rs57037487 chr4:1386652 A/G cg02980000 chr4:1222292 CTBP1 0.54 7.25 0.37 2.78e-12 Systolic blood pressure; LIHC cis rs694739 0.657 rs11231770 chr11:64140625 G/A cg23796481 chr11:64053134 BAD;GPR137 0.46 6.15 0.32 2.11e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.82 8.67 0.42 1.7e-16 Platelet count; LIHC trans rs3780486 0.505 rs959749 chr9:33147858 T/C cg20290983 chr6:43655470 MRPS18A 0.84 15.53 0.64 1.61e-41 IgG glycosylation; LIHC cis rs3753275 0.579 rs10779703 chr1:8596182 C/T cg20416874 chr1:8611966 RERE -0.49 -6.21 -0.32 1.54e-9 Educational attainment; LIHC cis rs701145 0.556 rs355787 chr3:153994502 T/C cg16511985 chr3:153974050 SGEF 0.42 8.92 0.43 2.92e-17 Coronary artery disease; LIHC trans rs9929218 0.529 rs35854485 chr16:68730855 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.86 19.28 0.72 1.36e-56 Colorectal cancer; LIHC cis rs12477438 0.520 rs4340581 chr2:99725025 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg12042659 chr19:58951599 ZNF132 -0.37 -6.39 -0.33 5.53e-10 Uric acid clearance; LIHC trans rs9929218 0.954 rs12924033 chr16:68822599 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.13 -0.4 8.18e-15 Colorectal cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12617538 chr9:69786570 NA 0.38 6.37 0.33 5.99e-10 Longevity; LIHC cis rs365132 0.517 rs7706790 chr5:176359136 C/T cg16309518 chr5:176445507 NA -0.49 -9.14 -0.44 5.47e-18 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs3008870 1.000 rs3008874 chr1:67431365 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.29 0.66 1.51e-44 Lymphocyte percentage of white cells; LIHC cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs9649213 0.593 rs6465662 chr7:97917801 A/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.82 -0.3 1.32e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs2304069 0.909 rs8073 chr5:149362400 T/G cg12661370 chr5:149340060 SLC26A2 -0.53 -6.46 -0.33 3.53e-10 HIV-1 control; LIHC cis rs651907 0.535 rs34648996 chr3:101511202 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.08 0.48 4.35e-21 Colorectal cancer; LIHC cis rs9486715 0.867 rs9480700 chr6:96965056 A/G cg06623918 chr6:96969491 KIAA0776 0.86 15.04 0.63 1.41e-39 Headache; LIHC cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs929354 0.772 rs10230895 chr7:157007038 T/C cg05182265 chr7:156933206 UBE3C -0.33 -6.16 -0.32 2.03e-9 Body mass index; LIHC cis rs8062405 0.929 rs11864750 chr16:28875204 A/T cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11785400 0.793 rs4736366 chr8:143742413 C/T cg24634471 chr8:143751801 JRK 0.49 7.84 0.39 5.77e-14 Schizophrenia; LIHC cis rs4728302 0.838 rs755664 chr7:133596671 C/G cg10665199 chr7:133106180 EXOC4 0.37 6.55 0.33 2.05e-10 Intelligence;Intelligence (multi-trait analysis); LIHC trans rs4824093 0.610 rs60036544 chr22:50264019 C/T cg09872104 chr7:134855509 C7orf49 -0.76 -6.09 -0.31 2.99e-9 Amyotrophic lateral sclerosis (sporadic); LIHC trans rs3942852 0.774 rs2270990 chr11:48184983 G/T cg03929089 chr4:120376271 NA -0.55 -7.58 -0.38 3.26e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs1506636 1.000 rs684548 chr7:123397102 A/T cg03229431 chr7:123269106 ASB15 0.61 12.16 0.55 1.59e-28 Plateletcrit;Platelet count; LIHC cis rs6988636 0.901 rs2602001 chr8:124195974 T/C cg15893493 chr8:124194847 FAM83A -0.71 -6.96 -0.35 1.79e-11 Urinary uromodulin levels; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg07133347 chr1:107600762 PRMT6 0.44 6.44 0.33 4.02e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11969893 0.850 rs9498409 chr6:101299966 G/A cg12253828 chr6:101329408 ASCC3 1.08 13.84 0.6 6.53e-35 Economic and political preferences (immigration/crime); LIHC cis rs3768617 0.528 rs4652778 chr1:183097420 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.57e-22 Fuchs's corneal dystrophy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13673319 chr1:174968334 CACYBP 0.48 6.47 0.33 3.45e-10 Pancreatic cancer; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg11618577 chr2:27665543 KRTCAP3 -0.43 -6.04 -0.31 3.92e-9 Total body bone mineral density; LIHC cis rs57920188 0.703 rs3813810 chr1:4088339 G/T cg20703997 chr1:4087676 NA 0.48 6.31 0.32 8.63e-10 Interleukin-17 levels; LIHC cis rs7772486 0.790 rs7742333 chr6:146159029 A/G cg23711669 chr6:146136114 FBXO30 -0.66 -11.67 -0.53 9.89e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs2072499 0.966 rs2842857 chr1:156168736 T/C cg24450063 chr1:156163899 SLC25A44 1.08 19.33 0.72 8.71e-57 Testicular germ cell tumor; LIHC cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg05552183 chr6:42928497 GNMT 0.49 7.06 0.36 9.43e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg07414643 chr4:187882934 NA 0.23 5.84 0.3 1.2e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs7618501 0.602 rs2071207 chr3:50159844 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.12 -0.44 6.7e-18 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17597744 chr8:53627099 RB1CC1 0.42 6.29 0.32 9.86e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4906332 0.782 rs12891288 chr14:103999750 C/T cg19000871 chr14:103996768 TRMT61A -0.54 -8.73 -0.43 1.16e-16 Coronary artery disease; LIHC cis rs919433 0.889 rs6711624 chr2:198207607 C/G cg10820045 chr2:198174542 NA -0.57 -9.24 -0.45 2.73e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs634534 0.532 rs12794370 chr11:65770413 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 6.0 0.31 5.13e-9 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs16828019 0.704 rs12031277 chr1:41491801 A/G cg03387723 chr1:41708464 SCMH1 -0.4 -6.27 -0.32 1.07e-9 Intelligence (multi-trait analysis); LIHC cis rs943466 1.000 rs6940353 chr6:33752550 G/A cg25922239 chr6:33757077 LEMD2 -0.47 -5.78 -0.3 1.66e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15813570 chr14:64854563 MTHFD1 0.39 6.13 0.31 2.41e-9 Cognitive function; LIHC cis rs7833790 0.724 rs6473310 chr8:82707981 A/G cg02079420 chr8:82753780 SNX16 0.37 6.86 0.35 3.3e-11 Diastolic blood pressure; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07431748 chr10:99094531 FRAT2 -0.42 -6.08 -0.31 3.24e-9 Systolic blood pressure; LIHC cis rs2066819 0.786 rs116934693 chr12:56696545 T/G cg26734620 chr12:56694298 CS 1.27 10.89 0.51 6.57e-24 Psoriasis vulgaris; LIHC trans rs1814175 0.645 rs11040703 chr11:50024961 C/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs2274273 1.000 rs1047556 chr14:55600282 A/T cg01864836 chr14:55583639 NA -0.36 -6.13 -0.31 2.43e-9 Protein biomarker; LIHC cis rs9296092 0.517 rs7743178 chr6:33470462 G/A cg13560919 chr6:33536144 NA -0.38 -6.06 -0.31 3.58e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs963731 0.649 rs9679498 chr2:39218458 G/C cg04010122 chr2:39346883 SOS1 -0.74 -6.0 -0.31 5.11e-9 Corticobasal degeneration; LIHC cis rs6542838 0.582 rs6542845 chr2:99537600 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.44 -6.3 -0.32 9.05e-10 Fear of minor pain; LIHC cis rs9649465 1.000 rs6950659 chr7:123361910 C/T cg03229431 chr7:123269106 ASB15 -0.37 -8.01 -0.4 1.82e-14 Migraine; LIHC cis rs9577381 0.628 rs9577380 chr13:112575568 A/G cg25344322 chr13:112575014 NA -0.24 -6.32 -0.32 8.19e-10 Axial length; LIHC cis rs11671005 0.695 rs8106061 chr19:58917990 G/C cg26874164 chr19:58962979 ZNF324B 0.76 9.91 0.47 1.65e-20 Mean platelet volume; LIHC cis rs9290065 0.622 rs11705811 chr3:160643787 C/T cg03342759 chr3:160939853 NMD3 -0.59 -8.08 -0.4 1.13e-14 Kawasaki disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06751603 chr19:11152063 SMARCA4 0.44 6.29 0.32 9.86e-10 Longevity; LIHC cis rs8027181 1.000 rs4776613 chr15:73080731 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.5 7.71 0.38 1.36e-13 Triglyceride levels; LIHC cis rs11122272 0.766 rs2808614 chr1:231550168 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.7 11.14 0.52 8.66e-25 Hemoglobin concentration; LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg08469215 chr1:156261351 TMEM79 0.4 6.59 0.34 1.68e-10 Tonsillectomy; LIHC cis rs4919087 0.884 rs4917762 chr10:98976471 G/T cg25902810 chr10:99078978 FRAT1 0.63 9.04 0.44 1.17e-17 Monocyte count; LIHC cis rs700651 0.789 rs10497812 chr2:198911245 A/G cg03934865 chr2:198174659 NA -0.46 -6.46 -0.33 3.6e-10 Intracranial aneurysm; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.49e-17 Prudent dietary pattern; LIHC cis rs17253792 0.822 rs8018142 chr14:56173288 C/T cg01858014 chr14:56050164 KTN1 -0.57 -6.51 -0.33 2.6200000000000003e-10 Putamen volume; LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg07157834 chr1:205819609 PM20D1 0.7 10.61 0.5 6.12e-23 Menarche (age at onset); LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg13752114 chr3:195489708 MUC4 0.68 11.16 0.52 6.98e-25 Lung disease severity in cystic fibrosis; LIHC cis rs2439831 0.867 rs486301 chr15:43836949 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.69 11.02 0.51 2.24e-24 Lung cancer in ever smokers; LIHC cis rs739401 0.611 rs7130841 chr11:3043658 A/G cg05729581 chr11:3078854 CARS -0.43 -5.95 -0.31 6.67e-9 Longevity; LIHC cis rs801193 0.660 rs10950049 chr7:66230860 T/C cg18252515 chr7:66147081 NA -0.44 -6.39 -0.33 5.46e-10 Aortic root size; LIHC cis rs4820294 0.669 rs732857 chr22:38060850 C/T cg26138144 chr22:38071188 LGALS1 0.43 7.96 0.4 2.62e-14 Fat distribution (HIV); LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.94 0.8 5.69e-79 Prudent dietary pattern; LIHC cis rs7107174 0.901 rs2512525 chr11:77923019 T/C cg02023728 chr11:77925099 USP35 0.45 8.19 0.41 5.16e-15 Testicular germ cell tumor; LIHC cis rs7116495 1.000 rs2885880 chr11:71655847 A/G cg26138937 chr11:71823887 C11orf51 -0.69 -6.93 -0.35 2.08e-11 Severe influenza A (H1N1) infection; LIHC trans rs975809 0.966 rs11004607 chr10:56622686 G/T cg10878170 chr12:12764498 CREBL2 0.4 6.13 0.31 2.41e-9 Carotid intima media thickness; LIHC cis rs2710642 0.721 rs1487074 chr2:62890551 T/C cg17519650 chr2:63277830 OTX1 0.51 7.47 0.37 6.57e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs7552404 1.000 rs441109 chr1:76120430 T/G cg10523679 chr1:76189770 ACADM -0.64 -8.79 -0.43 7.59e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs74544699 1.000 rs938094 chr4:74805942 C/G cg16072462 chr4:74847758 PF4 0.57 5.9 0.3 8.96e-9 Growth-regulated protein alpha levels; LIHC cis rs4561483 0.864 rs190461 chr16:12005745 A/G cg08843971 chr16:11963173 GSPT1 -0.36 -7.12 -0.36 6.6e-12 Testicular germ cell tumor; LIHC cis rs6912958 0.728 rs7773906 chr6:88251869 T/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.01 -0.4 1.84e-14 Monocyte percentage of white cells; LIHC trans rs9951602 0.512 rs4799249 chr18:76654370 A/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs9911578 1.000 rs6503870 chr17:56659018 C/T cg12560992 chr17:57184187 TRIM37 0.97 17.74 0.69 2.19e-50 Intelligence (multi-trait analysis); LIHC cis rs722599 0.683 rs17102847 chr14:75324780 A/G cg08847533 chr14:75593920 NEK9 -0.52 -8.0 -0.4 1.95e-14 IgG glycosylation; LIHC cis rs10751667 0.600 rs10902266 chr11:1005697 G/T ch.11.42038R chr11:967971 AP2A2 0.58 10.78 0.5 1.63e-23 Alzheimer's disease (late onset); LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.58 -8.3 -0.41 2.38e-15 Lymphocyte counts; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs1559088 0.501 rs35599132 chr19:33570554 G/A cg17764715 chr19:33622953 WDR88 0.48 6.36 0.33 6.64e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4845570 1.000 rs4845579 chr1:151770138 C/T cg07092448 chr1:151763213 TDRKH -0.93 -17.51 -0.69 1.78e-49 Coronary artery disease; LIHC cis rs523522 0.923 rs1048830 chr12:120882217 G/T cg12219531 chr12:120966889 COQ5 0.65 12.33 0.55 3.87e-29 High light scatter reticulocyte count; LIHC cis rs12922317 1.000 rs12922317 chr16:12077632 A/G cg09319797 chr16:12061715 TNFRSF17 0.4 7.09 0.36 7.68e-12 Schizophrenia; LIHC cis rs597539 0.652 rs604524 chr11:68629929 G/A cg06028808 chr11:68637592 NA 0.44 6.01 0.31 4.65e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs17685 0.712 rs11764119 chr7:75812358 T/G cg04610667 chr7:75704037 NA -0.35 -6.31 -0.32 8.63e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7927771 0.965 rs34958982 chr11:47547046 T/C cg20135002 chr11:47629003 NA -0.57 -10.06 -0.48 5.05e-21 Subjective well-being; LIHC cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.92 0.3 7.74e-9 Menopause (age at onset); LIHC cis rs13064411 0.696 rs7624994 chr3:113228009 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs9905704 0.647 rs10221208 chr17:57047885 T/C cg05425664 chr17:57184151 TRIM37 -0.44 -6.07 -0.31 3.37e-9 Testicular germ cell tumor; LIHC trans rs2727020 0.612 rs9787891 chr11:49413494 G/A cg18944383 chr4:111397179 ENPEP 0.31 7.29 0.37 2.14e-12 Coronary artery disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg10730208 chr12:58290540 NA 0.38 6.29 0.32 9.87e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2274273 0.905 rs8007944 chr14:55576816 A/C cg04306507 chr14:55594613 LGALS3 0.32 6.16 0.32 2.06e-9 Protein biomarker; LIHC trans rs1945213 0.694 rs10895985 chr11:55831595 T/C cg15704280 chr7:45808275 SEPT13 0.6 7.61 0.38 2.63e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg08888203 chr3:10149979 C3orf24 0.57 6.85 0.35 3.5e-11 Alzheimer's disease; LIHC cis rs244293 0.931 rs244308 chr17:53212053 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs722599 0.683 rs2058918 chr14:75288518 A/G cg08847533 chr14:75593920 NEK9 0.54 8.32 0.41 2.08e-15 IgG glycosylation; LIHC cis rs16854884 0.657 rs35959290 chr3:143725566 T/A cg06585982 chr3:143692056 C3orf58 0.49 5.95 0.31 6.51e-9 Economic and political preferences (feminism/equality); LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.76 0.54 4.77e-27 Prudent dietary pattern; LIHC cis rs7208859 0.623 rs9895785 chr17:29107708 C/T cg14067834 chr17:29058358 SUZ12P -0.66 -6.54 -0.33 2.21e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1005277 0.579 rs2505241 chr10:38442421 T/C cg27523141 chr10:43048294 ZNF37B 0.37 6.27 0.32 1.11e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg03034668 chr16:1723424 CRAMP1L -0.37 -6.4 -0.33 5.17e-10 Coronary artery disease; LIHC cis rs9649213 0.593 rs3801254 chr7:98010811 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.85 -0.3 1.15e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs8062405 0.964 rs78613234 chr16:28839425 T/C cg00204512 chr16:28754710 NA 0.34 6.39 0.33 5.51e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg25072359 chr17:41440525 NA 0.37 5.81 0.3 1.4e-8 Menopause (age at onset); LIHC cis rs986417 1.000 rs4901994 chr14:61090202 C/T cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs7116495 0.881 rs7930722 chr11:71737484 C/G cg26138937 chr11:71823887 C11orf51 -0.81 -8.04 -0.4 1.43e-14 Severe influenza A (H1N1) infection; LIHC cis rs7903847 0.642 rs11189182 chr10:99144186 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs57590327 0.503 rs898763 chr3:81513408 T/C cg07356753 chr3:81810745 GBE1 0.46 6.84 0.35 3.7e-11 Extraversion; LIHC cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg05564831 chr3:52568323 NT5DC2 0.39 6.27 0.32 1.07e-9 Bipolar disorder; LIHC cis rs600806 0.815 rs4970754 chr1:109969721 A/G cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.84 -0.3 1.2e-8 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.41 0.37 9.76e-13 Prudent dietary pattern; LIHC cis rs2404602 0.735 rs4886800 chr15:76678692 A/G cg03037974 chr15:76606532 NA -0.59 -9.91 -0.47 1.68e-20 Blood metabolite levels; LIHC cis rs7520050 0.966 rs1707321 chr1:46505309 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.86 0.3 1.09e-8 Red blood cell count;Reticulocyte count; LIHC cis rs35110281 0.755 rs4819270 chr21:45020919 G/A cg01579765 chr21:45077557 HSF2BP -0.35 -6.65 -0.34 1.13e-10 Mean corpuscular volume; LIHC cis rs1707322 0.686 rs3014251 chr1:46077428 G/C cg24296786 chr1:45957014 TESK2 0.43 6.17 0.32 1.92e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs36051895 0.664 rs10815154 chr9:5095538 G/A cg02405213 chr9:5042618 JAK2 -0.68 -11.61 -0.53 1.69e-26 Pediatric autoimmune diseases; LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg26354017 chr1:205819088 PM20D1 0.75 11.13 0.52 8.93e-25 Menarche (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg27309142 chr7:32801485 NA 0.36 6.08 0.31 3.27e-9 Hepatitis; LIHC cis rs858239 0.601 rs73272053 chr7:23155525 A/G cg18081818 chr7:23246105 NA -0.4 -5.98 -0.31 5.71e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs11969893 0.850 rs9386260 chr6:101329428 G/A cg12253828 chr6:101329408 ASCC3 1.05 13.02 0.58 9.19e-32 Economic and political preferences (immigration/crime); LIHC cis rs10078 0.559 rs2037077 chr5:447226 A/G cg08916839 chr5:415575 AHRR 0.63 12.9 0.57 2.6e-31 Fat distribution (HIV); LIHC cis rs7395581 0.918 rs10838693 chr11:47350553 G/C cg26139080 chr11:47293733 MADD -0.48 -8.06 -0.4 1.28e-14 HDL cholesterol; LIHC cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7927592 0.913 rs12283755 chr11:68371658 A/G cg01657329 chr11:68192670 LRP5 -0.48 -6.32 -0.32 8.2e-10 Total body bone mineral density; LIHC cis rs6964587 0.869 rs10278155 chr7:91532456 T/G cg17063962 chr7:91808500 NA -0.97 -18.03 -0.7 1.54e-51 Breast cancer; LIHC cis rs61925898 1 rs61925898 chr12:66779537 A/G cg16791601 chr12:66731901 HELB -0.48 -9.69 -0.46 8.58e-20 Basophil percentage of granulocytes;Basophil percentage of white cells; LIHC cis rs2839186 0.585 rs2839154 chr21:47637760 C/T cg09417038 chr21:47716443 C21orf57 0.52 8.16 0.4 6.37e-15 Testicular germ cell tumor; LIHC cis rs7116495 0.737 rs613971 chr11:71574910 G/A cg26138937 chr11:71823887 C11orf51 0.71 6.93 0.35 2.15e-11 Severe influenza A (H1N1) infection; LIHC cis rs2297440 0.527 rs4809318 chr20:62264760 G/A cg06363034 chr20:62225388 GMEB2 -0.45 -7.71 -0.38 1.4e-13 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC trans rs6600671 1.000 rs4844616 chr1:121171208 A/G cg09829573 chr1:144692074 NBPF9 -0.45 -8.3 -0.41 2.42e-15 Hip geometry; LIHC cis rs908922 0.887 rs7535188 chr1:152475899 G/A cg20991723 chr1:152506922 NA 0.5 8.33 0.41 1.96e-15 Hair morphology; LIHC cis rs860295 0.580 rs10908461 chr1:155275727 C/T cg02153340 chr1:155202674 NA -0.35 -6.14 -0.31 2.35e-9 Body mass index; LIHC cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg09222892 chr1:25734099 RHCE -0.47 -8.81 -0.43 6.34e-17 Erythrocyte sedimentation rate; LIHC cis rs12701220 0.817 rs7798459 chr7:1087965 C/T cg18765753 chr7:1198926 ZFAND2A -0.39 -5.72 -0.3 2.31e-8 Bronchopulmonary dysplasia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23333220 chr15:64679825 TRIP4 0.4 6.17 0.32 1.94e-9 Cognitive function; LIHC cis rs881375 0.967 rs7039505 chr9:123705945 A/T cg14580859 chr9:123691850 NA 0.39 6.86 0.35 3.27e-11 Rheumatoid arthritis; LIHC cis rs6502050 0.749 rs7406163 chr17:80086389 C/T cg11859384 chr17:80120422 CCDC57 0.43 5.95 0.31 6.76e-9 Life satisfaction; LIHC cis rs4575098 0.681 rs12727614 chr1:161097241 T/A cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.43 7.68 0.38 1.68e-13 Monocyte percentage of white cells; LIHC cis rs6952809 0.516 rs6952959 chr7:2440722 C/T cg23289794 chr7:2394357 EIF3B -0.67 -6.6 -0.34 1.61e-10 Multiple sclerosis; LIHC cis rs2742417 0.603 rs2742371 chr3:45782763 G/A cg04837898 chr3:45731254 SACM1L -0.51 -8.61 -0.42 2.64e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg06634786 chr22:41940651 POLR3H -0.77 -7.75 -0.39 1.09e-13 Vitiligo; LIHC cis rs992157 0.835 rs2292550 chr2:219140288 G/C cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.11 -0.55 2.39e-28 Colorectal cancer; LIHC cis rs1005277 0.579 rs1780116 chr10:38526621 C/T cg00409905 chr10:38381863 ZNF37A -0.57 -9.46 -0.46 5.23e-19 Extrinsic epigenetic age acceleration; LIHC cis rs875971 0.830 rs778715 chr7:65849209 C/T cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs2070488 0.965 rs6599209 chr3:38558197 A/G cg24069376 chr3:38537580 EXOG -0.39 -7.11 -0.36 6.72e-12 Electrocardiographic conduction measures; LIHC cis rs2072499 0.778 rs2247476 chr1:156190280 C/A cg24450063 chr1:156163899 SLC25A44 0.75 7.86 0.39 4.95e-14 Testicular germ cell tumor; LIHC cis rs798554 0.679 rs2527681 chr7:2892384 A/T cg04166393 chr7:2884313 GNA12 0.54 8.69 0.43 1.47e-16 Height; LIHC cis rs16828019 0.777 rs67460888 chr1:41469337 T/C cg03387723 chr1:41708464 SCMH1 -0.45 -6.91 -0.35 2.37e-11 Intelligence (multi-trait analysis); LIHC trans rs3812049 0.826 rs2409110 chr5:127433047 A/T cg16011800 chr17:1958478 HIC1 -0.52 -7.42 -0.37 9.6e-13 Lymphocyte counts;Red cell distribution width; LIHC cis rs611744 0.967 rs673015 chr8:109191669 C/T cg18478394 chr8:109455254 TTC35 0.44 7.69 0.38 1.58e-13 Dupuytren's disease; LIHC cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg02951883 chr7:2050386 MAD1L1 -0.78 -13.34 -0.58 5.71e-33 Bipolar disorder and schizophrenia; LIHC cis rs17106184 1.000 rs72898957 chr1:50966301 T/C cg07174182 chr1:51127561 FAF1 -0.61 -6.54 -0.33 2.26e-10 Type 2 diabetes; LIHC cis rs66569888 0.632 rs6728600 chr2:106898653 G/T cg23109721 chr2:106886537 NA -0.66 -6.18 -0.32 1.79e-9 Facial morphology (factor 23); LIHC cis rs1639906 0.895 rs35038526 chr7:2213106 A/G cg22963979 chr7:1858916 MAD1L1 0.4 5.72 0.3 2.34e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs17125944 0.505 rs10483618 chr14:53203590 T/C cg13660082 chr14:53194042 PSMC6 -0.44 -7.54 -0.38 4.28e-13 Alzheimer's disease (late onset); LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg01776012 chr4:56262702 TMEM165 0.53 6.17 0.32 1.98e-9 Glycated hemoglobin levels; LIHC cis rs2952156 1.000 rs2934967 chr17:37870378 G/A cg00129232 chr17:37814104 STARD3 -0.5 -8.81 -0.43 6.29e-17 Asthma; LIHC cis rs2806561 0.828 rs604030 chr1:23518227 T/C cg12483005 chr1:23474871 LUZP1 0.44 6.85 0.35 3.52e-11 Height; LIHC cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg05665937 chr4:1216051 CTBP1 0.45 6.08 0.31 3.23e-9 Obesity-related traits; LIHC cis rs1568889 0.877 rs12786351 chr11:28271122 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.46 5.83 0.3 1.28e-8 Bipolar disorder; LIHC cis rs10791097 0.694 rs1050071 chr11:130747231 C/G cg09137382 chr11:130731461 NA 0.41 5.85 0.3 1.15e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs10213084 1.000 rs28588661 chr4:147499726 G/A cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs7508679 1.000 rs7248104 chr19:7224431 A/G cg00428638 chr19:7224713 INSR 0.34 6.85 0.35 3.49e-11 Hypothyroidism; LIHC cis rs12458462 0.892 rs3786228 chr18:77464170 C/T cg11879182 chr18:77439856 CTDP1 -0.83 -14.0 -0.6 1.65e-35 Monocyte count; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg26266098 chr10:102756795 LZTS2 0.44 6.57 0.33 1.85e-10 Alopecia areata; LIHC cis rs8017423 0.967 rs2277514 chr14:90723059 T/C cg04374321 chr14:90722782 PSMC1 0.77 15.35 0.64 8.38e-41 Mortality in heart failure; LIHC cis rs2153535 0.580 rs6597327 chr6:8482157 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs6964587 0.692 rs12536220 chr7:91805595 T/G cg17063962 chr7:91808500 NA 0.67 12.15 0.55 1.72e-28 Breast cancer; LIHC cis rs459571 0.804 rs448918 chr9:136885979 G/A cg13789015 chr9:136890014 NCRNA00094 0.46 8.52 0.42 5.3e-16 Platelet distribution width; LIHC cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg07424592 chr7:64974309 NA 0.8 9.21 0.45 3.38e-18 Diabetic kidney disease; LIHC cis rs4631830 0.832 rs1585378 chr10:51523213 A/T cg20129853 chr10:51489980 NA -0.41 -8.78 -0.43 7.83e-17 Prostate-specific antigen levels; LIHC cis rs3736485 0.966 rs10220909 chr15:51762412 C/A cg08986416 chr15:51914746 DMXL2 -0.41 -6.11 -0.31 2.7e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9910055 0.509 rs9916444 chr17:42313512 C/G cg10896456 chr17:42255109 ASB16;C17orf65 0.41 7.29 0.37 2.12e-12 Total body bone mineral density; LIHC trans rs950169 0.649 rs12905952 chr15:84691261 G/A cg24036039 chr1:3397125 ARHGEF16 0.37 6.19 0.32 1.71e-9 Schizophrenia; LIHC cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg18252515 chr7:66147081 NA -1.24 -16.27 -0.66 1.72e-44 Diabetic kidney disease; LIHC cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg18867708 chr6:26865862 GUSBL1 -0.56 -8.55 -0.42 4.13e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs17685 0.523 rs10246583 chr7:75746667 C/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.21 -0.32 1.52e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1997103 1.000 rs1997103 chr7:55395390 C/G cg17469321 chr7:55412551 NA 0.47 6.98 0.35 1.56e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs16958440 1.000 rs75800624 chr18:44633605 G/C cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC cis rs738322 0.511 rs2267370 chr22:38576826 G/A cg25457927 chr22:38595422 NA -0.37 -8.8 -0.43 6.93e-17 Cutaneous nevi; LIHC cis rs2274273 0.905 rs10134800 chr14:55635209 A/G cg04306507 chr14:55594613 LGALS3 0.32 6.16 0.32 2.02e-9 Protein biomarker; LIHC cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg21448741 chr8:58168803 NA 0.37 6.02 0.31 4.48e-9 Developmental language disorder (linguistic errors); LIHC trans rs9388451 0.626 rs3799708 chr6:126078530 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.63 -10.63 -0.5 5.58e-23 Brugada syndrome; LIHC cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg18402987 chr7:1209562 NA 0.78 5.82 0.3 1.36e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6434928 1 rs6434928 chr2:198304577 G/A cg03934865 chr2:198174659 NA 0.55 8.35 0.41 1.71e-15 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7208859 0.673 rs999796 chr17:29159404 G/C cg13385521 chr17:29058706 SUZ12P 0.75 7.6 0.38 2.85e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg08677398 chr8:58056175 NA 0.36 6.1 0.31 2.81e-9 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg03721293 chr16:90014378 DEF8 -0.34 -6.03 -0.31 4.35e-9 Skin colour saturation; LIHC cis rs73591976 0.539 rs12446198 chr16:68125972 G/A cg05110241 chr16:68378359 PRMT7 -0.62 -6.82 -0.35 4.19e-11 HDL cholesterol; LIHC cis rs921968 0.643 rs4674321 chr2:219511368 G/A cg18887096 chr2:219472410 PLCD4 0.39 6.7 0.34 8.83e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.616 rs10839342 chr11:49742687 A/C cg03929089 chr4:120376271 NA -0.86 -16.84 -0.67 9.09e-47 Height; LIHC cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg08888203 chr3:10149979 C3orf24 0.54 6.27 0.32 1.06e-9 Alzheimer's disease; LIHC cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg21724239 chr8:58056113 NA 0.49 6.53 0.33 2.43e-10 Developmental language disorder (linguistic errors); LIHC cis rs35883536 0.967 rs1981134 chr1:101111205 G/T cg14515779 chr1:101123966 NA 0.64 12.35 0.56 3.09e-29 Monocyte count; LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg11965913 chr1:205819406 PM20D1 0.63 9.26 0.45 2.23e-18 Menarche (age at onset); LIHC cis rs12477438 0.834 rs1563108 chr2:99701153 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.59 -8.18 -0.4 5.63e-15 Chronic sinus infection; LIHC cis rs2710642 0.721 rs6545969 chr2:62891474 C/T cg17519650 chr2:63277830 OTX1 -0.47 -6.97 -0.35 1.65e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs6466055 0.720 rs6466057 chr7:104952483 A/G cg04380332 chr7:105027541 SRPK2 0.36 6.81 0.35 4.41e-11 Schizophrenia; LIHC cis rs10911232 0.524 rs4652773 chr1:183054827 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.52 0.49 1.34e-22 Hypertriglyceridemia; LIHC cis rs1568889 1.000 rs6484346 chr11:28040767 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 7.08 0.36 8.34e-12 Bipolar disorder; LIHC cis rs1670533 1.000 rs2045069 chr4:1052206 T/C cg27284194 chr4:1044797 NA 0.61 9.14 0.44 5.63e-18 Recombination rate (females); LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.52 -0.38 4.89e-13 Lymphocyte counts; LIHC cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg08132940 chr7:1081526 C7orf50 -0.83 -6.87 -0.35 3.01e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg25897951 chr4:1244024 CTBP1;C4orf42 -0.41 -5.94 -0.31 7.17e-9 Longevity; LIHC cis rs4969178 0.622 rs4129767 chr17:76403984 G/A cg05887092 chr17:76393375 PGS1 0.34 6.69 0.34 9.1e-11 HDL cholesterol levels; LIHC cis rs1682361 1 rs1682361 chr3:136734014 G/C cg21827317 chr3:136751795 NA 0.52 6.24 0.32 1.26e-9 Schizophrenia; LIHC cis rs35883536 0.647 rs10493929 chr1:101043928 A/C cg14515779 chr1:101123966 NA 0.48 6.91 0.35 2.35e-11 Monocyte count; LIHC cis rs17666538 0.535 rs1669613 chr8:617565 G/C cg23958373 chr8:599963 NA 0.79 6.09 0.31 3.03e-9 IgG glycosylation; LIHC cis rs916888 0.821 rs199512 chr17:44857352 T/C cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs763121 0.819 rs5757169 chr22:39003495 G/A cg21395723 chr22:39101663 GTPBP1 0.41 6.88 0.35 2.8e-11 Menopause (age at onset); LIHC trans rs2727020 0.658 rs10839278 chr11:49450847 G/C cg18944383 chr4:111397179 ENPEP 0.25 6.23 0.32 1.41e-9 Coronary artery disease; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg18037489 chr17:2275685 SGSM2 0.41 6.13 0.31 2.4e-9 Immature fraction of reticulocytes; LIHC cis rs10744422 1.000 rs4759382 chr12:123347609 C/T cg22842854 chr12:123319900 HIP1R 0.62 8.08 0.4 1.11e-14 Schizophrenia; LIHC cis rs7587476 0.784 rs13026390 chr2:215687075 C/T cg04004882 chr2:215674386 BARD1 -0.56 -7.68 -0.38 1.7e-13 Neuroblastoma; LIHC cis rs2072499 0.750 rs57056972 chr1:156159064 C/A cg25208724 chr1:156163844 SLC25A44 0.72 8.19 0.4 5.38e-15 Testicular germ cell tumor; LIHC trans rs6952808 0.723 rs55689856 chr7:2037215 G/A cg04565464 chr8:145669602 NFKBIL2 0.41 6.84 0.35 3.75e-11 Bipolar disorder and schizophrenia; LIHC cis rs11098499 0.866 rs12374352 chr4:120281977 C/T cg09307838 chr4:120376055 NA 0.63 9.65 0.46 1.17e-19 Corneal astigmatism; LIHC trans rs8073060 0.586 rs7214742 chr17:33981969 C/A cg19694781 chr19:47549865 TMEM160 -1.27 -13.8 -0.6 9.37e-35 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs10089 1.000 rs10060181 chr5:127475573 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.77 0.34 5.6e-11 Ileal carcinoids; LIHC cis rs17376456 1.000 rs17376456 chr5:93557702 C/T cg25358565 chr5:93447407 FAM172A -1.1 -9.96 -0.47 1.1e-20 Diabetic retinopathy; LIHC cis rs3806843 0.676 rs2569159 chr5:140030710 C/T cg19875535 chr5:140030758 IK -0.43 -6.99 -0.35 1.41e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs9368481 0.594 rs7768814 chr6:26892036 C/A cg12292205 chr6:26970375 C6orf41 0.43 7.17 0.36 4.55e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs6089829 0.889 rs6122348 chr20:61663921 C/T cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs9916302 0.904 rs34363096 chr17:37594294 G/A cg07936489 chr17:37558343 FBXL20 -0.84 -13.48 -0.59 1.65e-33 Glomerular filtration rate (creatinine); LIHC trans rs2797160 1.000 rs6569435 chr6:125998186 T/C cg05039488 chr6:79577232 IRAK1BP1 -0.45 -6.67 -0.34 1.06e-10 Endometrial cancer; LIHC cis rs13040088 0.935 rs3787513 chr20:61573736 G/A cg23096297 chr20:61557774 DIDO1 0.83 10.83 0.51 1.04e-23 Menopause (age at onset); LIHC cis rs427394 0.664 rs274722 chr5:6718668 C/T cg10857441 chr5:6722123 POLS -0.35 -6.02 -0.31 4.39e-9 Menopause (age at onset); LIHC cis rs1494373 0.543 rs3806329 chr1:220863423 C/T cg06786860 chr1:220876396 NA 0.42 6.41 0.33 4.84e-10 Response to antipsychotic therapy (extrapyramidal side effects); LIHC cis rs17401966 1.000 rs12141416 chr1:10327867 A/G cg15208524 chr1:10270712 KIF1B 0.42 6.43 0.33 4.27e-10 Hepatocellular carcinoma; LIHC cis rs3018712 0.532 rs7932726 chr11:68414727 T/C cg16797656 chr11:68205561 LRP5 -0.45 -5.87 -0.3 1.04e-8 Total body bone mineral density; LIHC cis rs7707921 0.881 rs74906189 chr5:81261923 A/G cg15871215 chr5:81402204 ATG10 -0.64 -6.05 -0.31 3.73e-9 Breast cancer; LIHC cis rs8180040 0.620 rs11709660 chr3:47074927 G/A cg27129171 chr3:47204927 SETD2 -0.54 -9.08 -0.44 8.92e-18 Colorectal cancer; LIHC trans rs7618501 0.521 rs3774759 chr3:49939120 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.46 6.88 0.35 2.86e-11 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.805 rs10881112 chr12:37956611 G/A cg26384229 chr12:38710491 ALG10B -0.49 -6.92 -0.35 2.24e-11 Bladder cancer; LIHC cis rs2637266 0.783 rs7914756 chr10:78476406 A/T cg18941641 chr10:78392320 NA -0.27 -5.81 -0.3 1.44e-8 Pulmonary function; LIHC cis rs9916302 0.861 rs3889368 chr17:37683231 C/T cg00129232 chr17:37814104 STARD3 -0.41 -6.61 -0.34 1.5e-10 Glomerular filtration rate (creatinine); LIHC cis rs796364 1.000 rs281771 chr2:200812202 A/C cg23649088 chr2:200775458 C2orf69 -0.47 -5.88 -0.3 9.84e-9 Schizophrenia; LIHC cis rs7572733 0.555 rs6434953 chr2:198929693 A/G cg00792783 chr2:198669748 PLCL1 0.41 5.92 0.31 7.71e-9 Dermatomyositis; LIHC cis rs7582720 1.000 rs72936838 chr2:203772984 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs35160687 0.644 rs4832265 chr2:86488265 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.35 5.75 0.3 2.01e-8 Night sleep phenotypes; LIHC cis rs5769707 0.681 rs4622843 chr22:50036916 T/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.58 -0.42 3.32e-16 Monocyte count;Monocyte percentage of white cells; LIHC trans rs3780486 0.522 rs7029897 chr9:33124042 T/C cg04842962 chr6:43655489 MRPS18A 0.88 18.74 0.71 2.05e-54 IgG glycosylation; LIHC cis rs11048434 0.736 rs7957321 chr12:9120154 C/T cg04155231 chr12:9217510 LOC144571 0.31 5.85 0.3 1.15e-8 Sjögren's syndrome; LIHC cis rs6748734 1.000 rs11898716 chr2:241828311 A/G cg08694578 chr2:241835147 C2orf54 -0.52 -7.17 -0.36 4.79e-12 Urinary metabolites; LIHC cis rs1707322 0.752 rs12024590 chr1:46127496 A/C cg03146154 chr1:46216737 IPP 0.57 9.74 0.47 5.94e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs6938574 0.672 rs6569520 chr6:128365034 C/G cg18796704 chr6:132216033 ENPP1 -0.34 -6.65 -0.34 1.14e-10 Menarche (age at onset); LIHC cis rs11583043 1.000 rs6682873 chr1:101470906 C/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.83 0.3 1.3e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs12477438 0.520 rs2632277 chr2:99778985 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 24.68 0.8 6.05e-78 Chronic sinus infection; LIHC cis rs597539 0.652 rs602805 chr11:68662076 A/T cg06028808 chr11:68637592 NA 0.43 5.73 0.3 2.22e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7131987 0.903 rs11050162 chr12:29420054 T/G cg12903224 chr12:29470962 FAR2 -0.42 -6.8 -0.35 4.72e-11 QT interval; LIHC cis rs1707322 0.721 rs10890337 chr1:46124527 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2243480 1.000 rs58062456 chr7:65394852 G/T cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18656765 chr4:159644664 PPID 0.41 6.28 0.32 1.02e-9 Pancreatic cancer; LIHC cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg03665457 chr10:38645376 HSD17B7P2 -0.45 -6.54 -0.33 2.3e-10 Extrinsic epigenetic age acceleration; LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg00091569 chr3:40428383 ENTPD3 0.4 6.83 0.35 4.01e-11 Renal cell carcinoma; LIHC cis rs7944735 0.508 rs2869531 chr11:47797402 G/C cg20307385 chr11:47447363 PSMC3 -0.51 -5.77 -0.3 1.81e-8 Intraocular pressure; LIHC cis rs7224737 1.000 rs7225608 chr17:40298326 G/A cg02450064 chr17:40260053 DHX58 -0.3 -6.36 -0.33 6.33e-10 Fibrinogen levels; LIHC cis rs28602288 1 rs28602288 chr19:41388740 C/T cg14550611 chr19:41354682 CYP2A6 0.4 5.92 0.3 7.75e-9 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); LIHC cis rs6448317 0.539 rs11931422 chr4:24936925 T/C cg21108841 chr4:24914750 CCDC149 -0.48 -6.55 -0.33 2.14e-10 Heschl's gyrus morphology; LIHC cis rs1395 0.813 rs11685326 chr2:27453679 A/G cg23587288 chr2:27483067 SLC30A3 -0.33 -6.0 -0.31 5.08e-9 Blood metabolite levels; LIHC cis rs2066819 1.000 rs76466034 chr12:56719450 G/A cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs929354 0.566 rs6979947 chr7:157005863 C/T cg17757837 chr7:157058334 UBE3C -0.66 -9.4 -0.45 7.82e-19 Body mass index; LIHC cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg18867708 chr6:26865862 GUSBL1 -0.48 -7.33 -0.37 1.68e-12 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.966 rs998658 chr10:35408654 A/G cg03585969 chr10:35415529 CREM 0.8 11.92 0.54 1.24e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg02290350 chr8:58132656 NA -0.44 -8.95 -0.44 2.25e-17 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.645 rs28549248 chr11:50042740 C/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs6840360 0.615 rs4696268 chr4:152464723 G/A cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.37 0.45 9.93e-19 Bipolar disorder; LIHC cis rs11122272 0.732 rs2808605 chr1:231540187 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.77e-22 Hemoglobin concentration; LIHC cis rs644799 1.000 rs593665 chr11:95574302 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.51 0.46 3.43e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6570726 0.935 rs384806 chr6:145814889 C/G cg23711669 chr6:146136114 FBXO30 0.55 9.84 0.47 2.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6762 0.748 rs1130663 chr11:837582 G/A cg15787769 chr11:842744 TSPAN4;POLR2L -0.61 -7.41 -0.37 9.84e-13 Mean platelet volume; LIHC cis rs798554 0.724 rs798498 chr7:2795882 T/G cg19346786 chr7:2764209 NA -0.44 -6.75 -0.34 6.37e-11 Height; LIHC cis rs7917772 0.636 rs7079231 chr10:104527341 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 6.29 0.32 9.72e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs13108904 0.557 rs1680041 chr4:1238521 C/T cg19318889 chr4:1322082 MAEA -0.62 -9.98 -0.47 9.33e-21 Obesity-related traits; LIHC cis rs4911259 0.552 rs6057663 chr20:31463071 G/T cg13636640 chr20:31349939 DNMT3B -0.61 -10.78 -0.5 1.56e-23 Inflammatory bowel disease; LIHC cis rs8017423 0.967 rs55894943 chr14:90714799 A/G cg04374321 chr14:90722782 PSMC1 0.74 14.52 0.62 1.53e-37 Mortality in heart failure; LIHC cis rs4684776 0.676 rs2067471 chr3:11299602 A/G cg00170343 chr3:11313890 ATG7 -0.48 -6.47 -0.33 3.31e-10 Small vessel stroke; LIHC trans rs9747201 1.000 rs57405744 chr17:80177465 A/G cg07393940 chr7:158741817 NA 0.54 6.25 0.32 1.21e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs533581 0.866 rs562812 chr16:88970944 G/A cg03970086 chr16:88974840 CBFA2T3 0.35 7.04 0.36 1.03e-11 Social autistic-like traits; LIHC cis rs244293 0.931 rs244345 chr17:53196977 A/T cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.58 -0.38 3.37e-13 Menarche (age at onset); LIHC cis rs12908161 1.000 rs36033486 chr15:85319692 A/G cg17507749 chr15:85114479 UBE2QP1 0.63 7.18 0.36 4.38e-12 Schizophrenia; LIHC cis rs12579753 0.833 rs12579530 chr12:82163930 A/C cg07988820 chr12:82153109 PPFIA2 -0.51 -6.39 -0.33 5.33e-10 Resting heart rate; LIHC cis rs477692 1.000 rs473073 chr10:131429646 G/T cg05714579 chr10:131428358 MGMT 0.44 7.14 0.36 5.63e-12 Response to temozolomide; LIHC cis rs11628318 0.614 rs7154538 chr14:103068112 A/G cg01864069 chr14:103024347 NA -0.45 -7.35 -0.37 1.52e-12 Platelet count; LIHC cis rs4629710 0.592 rs11759793 chr6:131546384 G/A cg12606694 chr6:131520996 AKAP7 0.63 7.35 0.37 1.47e-12 Multiple myeloma (IgH translocation); LIHC cis rs9633740 0.578 rs11185982 chr10:82305627 C/T cg01528321 chr10:82214614 TSPAN14 0.74 7.74 0.39 1.15e-13 Post bronchodilator FEV1; LIHC cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg00684032 chr4:1343700 KIAA1530 0.51 7.75 0.39 1.08e-13 Obesity-related traits; LIHC cis rs7100689 0.646 rs6585946 chr10:82118292 G/T cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs4319547 1.000 rs4319547 chr12:123079035 A/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.25 -0.36 2.85e-12 Body mass index; LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg24209194 chr3:40518798 ZNF619 0.56 8.11 0.4 8.97e-15 Renal cell carcinoma; LIHC cis rs4319547 0.508 rs10846826 chr12:122894987 C/T cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.35 -0.37 1.47e-12 Body mass index; LIHC cis rs2075371 0.863 rs1421479 chr7:133949345 T/G cg11752832 chr7:134001865 SLC35B4 0.47 6.03 0.31 4.15e-9 Mean platelet volume; LIHC cis rs9611565 0.649 rs5758442 chr22:42133060 T/C cg03806693 chr22:41940476 POLR3H 0.78 8.87 0.43 4.01e-17 Vitiligo; LIHC cis rs7408868 1.000 rs7254735 chr19:15263385 A/G cg14696996 chr19:15285081 NOTCH3 0.48 6.45 0.33 3.93e-10 Pulse pressure; LIHC cis rs9640161 0.789 rs60283368 chr7:150023258 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.89 -0.43 3.45e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs7551222 0.752 rs4328119 chr1:204564986 C/T cg20240347 chr1:204465584 NA -0.31 -6.25 -0.32 1.21e-9 Schizophrenia; LIHC cis rs9549328 0.800 rs1317507 chr13:113631780 G/T cg00071026 chr13:113650936 MCF2L -0.38 -6.19 -0.32 1.77e-9 Systolic blood pressure; LIHC cis rs10752881 1.000 rs6658501 chr1:182991417 C/T ch.1.3577855R chr1:183094577 LAMC1 -0.61 -10.99 -0.51 2.79e-24 Colorectal cancer; LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg14004847 chr7:1930337 MAD1L1 -0.42 -5.91 -0.3 8.35e-9 Bipolar disorder and schizophrenia; LIHC cis rs11822910 0.645 rs7122734 chr11:57190420 C/T cg00522883 chr11:57194120 SLC43A3 -0.56 -7.24 -0.36 3.06e-12 Platelet distribution width; LIHC cis rs12711979 0.509 rs882418 chr2:3820113 A/G cg17052675 chr2:3827356 NA -0.64 -9.65 -0.46 1.22e-19 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs12887734 0.524 rs4900599 chr14:104283444 G/T cg24130564 chr14:104152367 KLC1 -0.43 -7.02 -0.36 1.17e-11 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg07936541 chr2:98206095 ANKRD36B -0.44 -6.2 -0.32 1.64e-9 Urinary tract infection frequency; LIHC cis rs6596100 0.538 rs72799458 chr5:132188063 C/T cg02081065 chr5:132209139 LEAP2 0.29 6.34 0.32 7.38e-10 Breast cancer; LIHC cis rs950169 0.922 rs4842940 chr15:84831225 C/T cg12863693 chr15:85201151 NMB -0.4 -5.8 -0.3 1.47e-8 Schizophrenia; LIHC cis rs921968 0.643 rs471846 chr2:219432237 C/T cg17980119 chr2:219472607 PLCD4 0.34 5.79 0.3 1.62e-8 Mean corpuscular hemoglobin concentration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg12298905 chr1:214162308 PROX1 -0.49 -6.09 -0.31 3.03e-9 Systolic blood pressure; LIHC trans rs4566648 0.593 rs7356198 chr4:84173186 G/A cg06219686 chr17:29421884 NF1 -0.5 -6.04 -0.31 4e-9 Monocyte count; LIHC cis rs2549003 1.000 rs13170412 chr5:131823519 A/G cg21138405 chr5:131827807 IRF1 0.36 8.92 0.43 2.77e-17 Asthma (sex interaction); LIHC cis rs1113500 0.862 rs2336128 chr1:108640739 G/T cg06207961 chr1:108661230 NA 0.38 7.45 0.37 7.62e-13 Growth-regulated protein alpha levels; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg10755058 chr3:40428713 ENTPD3 -0.41 -7.1 -0.36 7.3e-12 Renal cell carcinoma; LIHC cis rs1552244 0.882 rs56224841 chr3:10044014 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg13866156 chr1:1669148 SLC35E2 -0.68 -12.85 -0.57 4.17e-31 Body mass index; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs9457247 0.602 rs9459854 chr6:167465882 C/T cg23791538 chr6:167370224 RNASET2 -0.51 -7.81 -0.39 6.86e-14 Crohn's disease; LIHC cis rs9916302 0.898 rs8072297 chr17:37478048 A/T cg07936489 chr17:37558343 FBXL20 0.83 12.91 0.57 2.46e-31 Glomerular filtration rate (creatinine); LIHC trans rs12310956 0.532 rs11052920 chr12:33955891 T/G cg26384229 chr12:38710491 ALG10B 0.44 6.18 0.32 1.78e-9 Morning vs. evening chronotype; LIHC cis rs6840360 0.615 rs4696267 chr4:152464500 A/G cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs7116495 0.881 rs642618 chr11:71788193 G/A cg26138937 chr11:71823887 C11orf51 -0.68 -6.84 -0.35 3.56e-11 Severe influenza A (H1N1) infection; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25485084 chr12:118809325 TAOK3 0.37 6.2 0.32 1.59e-9 Cognitive function; LIHC cis rs1144333 0.655 rs12402347 chr1:76447986 C/T cg10523679 chr1:76189770 ACADM 0.44 5.91 0.3 8.5e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs10506458 0.915 rs60094497 chr12:63394838 T/G cg22491629 chr6:157744540 C6orf35 -0.61 -11.0 -0.51 2.6e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs548181 0.611 rs2849225 chr11:125415936 A/G cg03464685 chr11:125439445 EI24 1.5 15.23 0.64 2.46e-40 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs892961 0.932 rs11658267 chr17:75411884 C/T cg05865280 chr17:75406074 SEPT9 -0.64 -13.2 -0.58 1.91e-32 Airflow obstruction; LIHC cis rs1401999 0.628 rs7639048 chr3:183746044 A/G cg01324343 chr3:183735012 ABCC5 0.62 9.85 0.47 2.57e-20 Anterior chamber depth; LIHC cis rs3008870 1.000 rs3008888 chr1:67368965 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.96 16.52 0.67 1.77e-45 Lymphocyte percentage of white cells; LIHC trans rs6058796 1.000 rs6141777 chr20:31249947 C/T cg02600331 chr11:130417168 NA 0.35 7.44 0.37 8.33e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs6840360 1.000 rs6840360 chr4:152604031 C/T cg22705602 chr4:152727874 NA -0.28 -5.75 -0.3 1.99e-8 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.11 0.55 2.38e-28 Height; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs11148252 0.740 rs7981050 chr13:52755149 C/T cg00495681 chr13:53174319 NA 0.38 5.91 0.3 8.34e-9 Lewy body disease; LIHC cis rs1789 0.653 rs13142069 chr4:15593692 C/T cg21329975 chr4:15471214 CC2D2A 0.37 5.96 0.31 6.35e-9 Blood protein levels; LIHC cis rs2832191 0.720 rs7277028 chr21:30494604 T/C cg08807101 chr21:30365312 RNF160 -0.57 -8.97 -0.44 1.99e-17 Dental caries; LIHC cis rs477692 0.870 rs532248 chr10:131414156 T/A cg19680672 chr10:131412579 MGMT -0.42 -6.42 -0.33 4.45e-10 Response to temozolomide; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05736393 chr2:74775957 LOXL3 0.45 6.1 0.31 2.89e-9 Lung function (FEV1/FVC); LIHC cis rs12497850 0.897 rs9884022 chr3:48956862 G/C cg07636037 chr3:49044803 WDR6 0.93 16.95 0.68 3.21e-47 Parkinson's disease; LIHC cis rs7020830 0.861 rs13289001 chr9:37311592 A/G cg14294708 chr9:37120828 ZCCHC7 1.17 26.37 0.82 2.15e-84 Schizophrenia; LIHC cis rs9858542 0.953 rs11706370 chr3:49441091 G/A cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7149337 0.805 rs4350491 chr14:51675798 A/G cg23942311 chr14:51606299 NA 0.32 6.3 0.32 9.34e-10 Cancer; LIHC trans rs7618501 0.522 rs73077175 chr3:49774658 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.6 -10.02 -0.48 6.87e-21 Intelligence (multi-trait analysis); LIHC cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg24675658 chr1:53192096 ZYG11B 0.58 9.13 0.44 6.03e-18 Monocyte count; LIHC cis rs17496827 0.753 rs4673024 chr2:223361153 G/A cg25565276 chr2:223520875 FARSB 0.46 6.74 0.34 6.91e-11 Anorexia nervosa; LIHC cis rs1448094 0.512 rs10779216 chr12:86240315 A/G cg02569458 chr12:86230093 RASSF9 -0.46 -6.18 -0.32 1.78e-9 Major depressive disorder; LIHC cis rs13161895 0.887 rs863231 chr5:179409613 C/T cg02702477 chr5:179499311 RNF130 0.63 9.02 0.44 1.34e-17 LDL cholesterol; LIHC cis rs4478037 0.822 rs3924696 chr3:33122013 T/C cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.04 -0.36 1.05e-11 Major depressive disorder; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 22.54 0.77 1.29e-69 Prudent dietary pattern; LIHC cis rs17106184 1.000 rs2137676 chr1:51217839 C/G cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs4407350 0.818 rs5765751 chr22:44926018 A/T cg11695653 chr22:44894386 LDOC1L 0.39 6.44 0.33 4.06e-10 Intelligence (multi-trait analysis); LIHC trans rs11148252 0.811 rs9535895 chr13:52765847 G/A cg18335740 chr13:41363409 SLC25A15 0.4 6.78 0.34 5.14e-11 Lewy body disease; LIHC cis rs3806843 0.735 rs778596 chr5:140037272 G/A cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10916814 0.632 rs12409100 chr1:20903207 G/A cg24502330 chr1:20914028 CDA -0.3 -6.6 -0.34 1.55e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.85 9.0 0.44 1.6e-17 Platelet count; LIHC cis rs1059312 0.772 rs11609637 chr12:129300202 T/G cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.78 -17.0 -0.68 2.14e-47 Systemic lupus erythematosus; LIHC trans rs7618501 1.000 rs7372725 chr3:49790544 C/A cg21659725 chr3:3221576 CRBN -0.99 -19.64 -0.73 4.88e-58 Intelligence (multi-trait analysis); LIHC trans rs9641123 0.607 rs2677085 chr7:93255334 T/C cg09745688 chr16:2908918 PRSS22 -0.37 -6.46 -0.33 3.64e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs7918232 0.830 rs7087033 chr10:27392522 A/G cg14442939 chr10:27389572 ANKRD26 0.71 7.0 0.35 1.36e-11 Breast cancer; LIHC cis rs28374715 0.580 rs8030228 chr15:41636867 A/G cg18705301 chr15:41695430 NDUFAF1 -1.05 -15.34 -0.64 9.16e-41 Ulcerative colitis; LIHC cis rs9560113 1.000 rs9560113 chr13:112183348 A/G cg14154082 chr13:112174009 NA 0.29 6.24 0.32 1.32e-9 Menarche (age at onset); LIHC trans rs2832077 0.943 rs4816332 chr21:30201706 T/C cg14791747 chr16:20752902 THUMPD1 0.49 6.37 0.33 6.14e-10 Cognitive test performance; LIHC cis rs921968 0.643 rs1516086 chr2:219431535 C/T cg18887096 chr2:219472410 PLCD4 0.37 6.43 0.33 4.28e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs739401 0.611 rs417957 chr11:3046231 A/G cg08508325 chr11:3079039 CARS -0.32 -6.87 -0.35 3.02e-11 Longevity; LIHC cis rs6545883 0.895 rs2177961 chr2:61560264 T/C cg14146966 chr2:61757674 XPO1 -0.43 -7.15 -0.36 5.36e-12 Tuberculosis; LIHC cis rs6570726 0.935 rs368848 chr6:145855281 A/T cg23711669 chr6:146136114 FBXO30 0.56 10.01 0.48 7.29e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs17685 0.697 rs2302437 chr7:75677016 G/A cg01364799 chr7:75623366 TMEM120A 0.51 7.6 0.38 2.91e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg03351412 chr1:154909251 PMVK 0.71 10.52 0.49 1.36e-22 Prostate cancer; LIHC cis rs2153535 0.541 rs9392222 chr6:8467649 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs11997175 0.558 rs6468207 chr8:33798095 G/A ch.8.33884649F chr8:33765107 NA -0.4 -6.44 -0.33 3.96e-10 Body mass index; LIHC cis rs6840360 0.809 rs6846809 chr4:152730201 A/G cg22705602 chr4:152727874 NA 0.33 6.96 0.35 1.75e-11 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs3885839 chr7:65290403 G/T cg12463550 chr7:65579703 CRCP 0.7 7.15 0.36 5.32e-12 Diabetic kidney disease; LIHC cis rs2075371 0.897 rs1646743 chr7:134003451 C/A cg11752832 chr7:134001865 SLC35B4 0.43 6.43 0.33 4.31e-10 Mean platelet volume; LIHC trans rs2243480 1.000 rs35735127 chr7:65300423 G/T cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs1448094 0.512 rs6539925 chr12:86244358 A/G cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs7428 0.527 rs3184780 chr2:85549547 C/T cg24342717 chr2:85555507 TGOLN2 -0.77 -10.74 -0.5 2.31e-23 Ear protrusion; LIHC cis rs2834256 0.530 rs7281554 chr21:34928355 C/T cg14850771 chr21:34775459 IFNGR2 0.47 7.38 0.37 1.18e-12 Red cell distribution width; LIHC cis rs4555082 0.830 rs2816648 chr14:105708289 C/T cg13114125 chr14:105738426 BRF1 -0.76 -10.06 -0.48 5.07e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg09455208 chr3:40491958 NA -0.41 -8.44 -0.42 9e-16 Renal cell carcinoma; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs11711311 0.826 rs13077644 chr3:113467777 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.42 8.04 0.4 1.45e-14 IgG glycosylation; LIHC cis rs2836974 0.666 rs4624474 chr21:40686327 T/C cg06238570 chr21:40685208 BRWD1 -0.55 -9.18 -0.44 4.34e-18 Cognitive function; LIHC cis rs7520050 0.966 rs785492 chr1:46583607 G/A cg03146154 chr1:46216737 IPP -0.38 -6.25 -0.32 1.24e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1046896 0.594 rs9914570 chr17:80783721 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.4 5.95 0.31 6.48e-9 Glycated hemoglobin levels; LIHC cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg07424592 chr7:64974309 NA 0.84 9.64 0.46 1.3e-19 Diabetic kidney disease; LIHC cis rs16828019 0.852 rs12022978 chr1:41554088 A/G cg20697417 chr1:41786797 NA 0.31 5.91 0.3 8.23e-9 Intelligence (multi-trait analysis); LIHC cis rs40363 0.645 rs250629 chr16:3525431 C/A cg22508957 chr16:3507546 NAT15 0.49 8.8 0.43 6.84e-17 Tuberculosis; LIHC cis rs6582630 0.555 rs11181684 chr12:38388000 T/C cg26384229 chr12:38710491 ALG10B 0.57 7.95 0.39 2.73e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs6502050 0.799 rs6416859 chr17:80111442 G/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg10295955 chr4:187884368 NA -0.98 -22.14 -0.77 5.34e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs9888615 0.926 rs2884345 chr14:53323211 A/G cg00686598 chr14:53173677 PSMC6 0.48 6.27 0.32 1.08e-9 Systolic blood pressure; LIHC trans rs8073060 0.586 rs225300 chr17:33922428 C/T cg19694781 chr19:47549865 TMEM160 -1.23 -12.78 -0.57 7.71e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs986417 0.901 rs1955688 chr14:60989237 G/A cg27398547 chr14:60952738 C14orf39 0.75 8.1 0.4 9.98e-15 Gut microbiota (bacterial taxa); LIHC cis rs1385374 0.858 rs12321643 chr12:129302867 A/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.62 7.57 0.38 3.51e-13 Systemic lupus erythematosus; LIHC cis rs35306767 0.761 rs11253557 chr10:1043667 C/T cg20503657 chr10:835505 NA 0.84 8.04 0.4 1.48e-14 Eosinophil percentage of granulocytes; LIHC cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17854409 0.803 rs1048100 chr20:61472073 C/A cg07645718 chr20:61493192 TCFL5 0.69 5.79 0.3 1.61e-8 Obesity-related traits; LIHC cis rs7523273 0.565 rs2796239 chr1:207902206 G/A cg22525895 chr1:207977042 MIR29B2 -0.54 -8.24 -0.41 3.61e-15 Schizophrenia; LIHC cis rs4780401 0.609 rs4781142 chr16:11808806 T/C cg01061890 chr16:11836724 TXNDC11 -0.65 -10.36 -0.49 4.78e-22 Rheumatoid arthritis; LIHC cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.15e-9 Menopause (age at onset); LIHC cis rs1451375 0.572 rs11575463 chr7:50547173 A/G cg14593290 chr7:50529359 DDC -0.63 -10.31 -0.49 6.98e-22 Malaria; LIHC cis rs2997447 0.761 rs74384164 chr1:26430379 C/T cg19633962 chr1:26362018 EXTL1 -0.66 -5.86 -0.3 1.11e-8 QRS complex (12-leadsum); LIHC cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Bipolar disorder; LIHC cis rs1065852 0.510 rs5751247 chr22:42633054 T/C cg00645731 chr22:42541494 CYP2D7P1 0.39 6.5 0.33 2.87e-10 Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels); LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg09033563 chr22:24373618 LOC391322 -0.49 -6.87 -0.35 3e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs2727020 0.619 rs1829979 chr11:49436875 T/G cg03929089 chr4:120376271 NA -0.67 -9.86 -0.47 2.44e-20 Coronary artery disease; LIHC cis rs4808199 1.000 rs60003758 chr19:19557353 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.42 5.94 0.31 7.05e-9 Nonalcoholic fatty liver disease; LIHC cis rs11792861 0.926 rs72607169 chr9:111832471 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.82 0.43 6.02e-17 Menarche (age at onset); LIHC cis rs28530618 0.603 rs4594522 chr20:31254984 T/C cg13636640 chr20:31349939 DNMT3B -0.42 -5.96 -0.31 6.2e-9 Birth weight; LIHC cis rs7223966 0.960 rs113155878 chr17:61706560 C/A cg05941027 chr17:61774174 LIMD2 0.36 7.5 0.38 5.41e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs17106184 0.892 rs72900940 chr1:51124579 C/T cg07174182 chr1:51127561 FAF1 -0.76 -8.09 -0.4 1.08e-14 Type 2 diabetes; LIHC cis rs9473924 0.542 rs9473952 chr6:50921779 T/C cg14470998 chr6:50812995 TFAP2B 0.81 7.49 0.38 5.86e-13 Body mass index; LIHC cis rs11148252 0.774 rs7993748 chr13:52941631 C/T cg00495681 chr13:53174319 NA 0.4 6.66 0.34 1.11e-10 Lewy body disease; LIHC cis rs9896933 0.615 rs2379354 chr17:80704385 G/A cg20578329 chr17:80767326 TBCD -0.75 -7.19 -0.36 4.11e-12 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs9291683 0.588 rs3756236 chr4:10013463 T/A cg11266682 chr4:10021025 SLC2A9 0.33 7.14 0.36 5.5e-12 Bone mineral density; LIHC cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.5 6.86 0.35 3.29e-11 Schizophrenia; LIHC cis rs6088580 0.634 rs2184836 chr20:32963369 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs9296092 0.560 rs9469502 chr6:33526648 G/A cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs9916302 0.768 rs62077464 chr17:37656056 C/G cg00129232 chr17:37814104 STARD3 -0.43 -6.89 -0.35 2.76e-11 Glomerular filtration rate (creatinine); LIHC cis rs7927771 1.000 rs10838738 chr11:47663049 A/G cg18512352 chr11:47633146 NA -0.25 -5.86 -0.3 1.07e-8 Subjective well-being; LIHC cis rs4423214 0.959 rs12793224 chr11:71168710 G/A cg24826892 chr11:71159390 DHCR7 0.48 6.16 0.32 1.99e-9 Vitamin D levels; LIHC trans rs783540 0.933 rs2567636 chr15:83263428 C/T cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.66 -0.34 1.09e-10 Schizophrenia; LIHC cis rs35306767 0.855 rs12781100 chr10:838636 C/T cg10556349 chr10:835070 NA 0.66 5.85 0.3 1.18e-8 Eosinophil percentage of granulocytes; LIHC cis rs1371867 0.846 rs1788197 chr8:101290928 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -8.9 -0.43 3.27e-17 Atrioventricular conduction; LIHC cis rs2408955 0.522 rs7139330 chr12:48483484 A/C cg21466736 chr12:48725269 NA 0.62 9.0 0.44 1.57e-17 Glycated hemoglobin levels; LIHC cis rs6500602 0.702 rs2270366 chr16:4558615 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 -0.42 -6.07 -0.31 3.39e-9 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24435866 chr1:154976595 ZBTB7B 0.46 6.52 0.33 2.57e-10 Lung function (FEV1/FVC); LIHC cis rs13401104 0.796 rs1466205 chr2:237121194 A/G cg19324714 chr2:237145437 ASB18 0.37 5.85 0.3 1.13e-8 Educational attainment; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg20841156 chr12:120652778 PXN 0.41 6.22 0.32 1.46e-9 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs13088318 0.521 rs2553415 chr3:101095630 T/A cg19452782 chr3:101232218 SENP7 -0.41 -6.07 -0.31 3.33e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6429082 0.846 rs2270538 chr1:235602404 G/A cg26050004 chr1:235667680 B3GALNT2 -0.48 -7.2 -0.36 3.94e-12 Adiposity; LIHC cis rs7085104 0.700 rs743572 chr10:104597152 A/G cg15744005 chr10:104629667 AS3MT -0.41 -9.16 -0.44 5.04e-18 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs12142240 0.698 rs1984490 chr1:46858734 C/T cg00530320 chr1:46809349 NSUN4 -0.53 -5.9 -0.3 8.71e-9 Menopause (age at onset); LIHC cis rs2404602 0.647 rs11855296 chr15:77092962 C/T cg23625390 chr15:77176239 SCAPER -0.53 -8.85 -0.43 4.95e-17 Blood metabolite levels; LIHC cis rs240764 0.853 rs2001102 chr6:100978351 C/T cg09795085 chr6:101329169 ASCC3 -0.43 -5.78 -0.3 1.65e-8 Neuroticism; LIHC cis rs4718428 0.924 rs6971897 chr7:66412774 T/A cg18252515 chr7:66147081 NA -0.49 -6.09 -0.31 2.98e-9 Corneal structure; LIHC cis rs6782228 0.606 rs2712404 chr3:128332679 C/T cg16766828 chr3:128327626 NA 0.42 6.59 0.34 1.63e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7208859 0.673 rs3764421 chr17:29167653 A/C cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs743757 0.938 rs2236959 chr3:50441627 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.7 0.38 1.45e-13 Diastolic blood pressure; LIHC cis rs700651 0.789 rs5007118 chr2:198909738 G/C cg00792783 chr2:198669748 PLCL1 0.45 6.5 0.33 2.81e-10 Intracranial aneurysm; LIHC cis rs910316 0.737 rs175071 chr14:75498177 A/G cg11812906 chr14:75593930 NEK9 -0.74 -13.82 -0.6 8.21e-35 Height; LIHC cis rs4919087 0.781 rs7901853 chr10:99082360 T/C cg25902810 chr10:99078978 FRAT1 0.69 10.43 0.49 2.68e-22 Monocyte count; LIHC cis rs11098499 0.909 rs28714195 chr4:120316950 A/T cg09307838 chr4:120376055 NA 0.77 11.88 0.54 1.75e-27 Corneal astigmatism; LIHC trans rs2363709 1.000 rs6770280 chr3:67416712 T/C cg22969669 chr19:19613165 GATAD2A 0.66 6.13 0.31 2.48e-9 IgE levels; LIHC cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg10755058 chr3:40428713 ENTPD3 -0.33 -5.76 -0.3 1.91e-8 Renal cell carcinoma; LIHC cis rs7618501 1.000 rs9872864 chr3:49792023 A/G cg21467203 chr3:49911342 NA 0.39 6.64 0.34 1.2e-10 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16140913 chr4:8430389 ACOX3 0.41 6.05 0.31 3.79e-9 Pancreatic cancer; LIHC cis rs1801251 1.000 rs991873 chr2:233711046 A/G cg25237894 chr2:233734115 C2orf82 -0.58 -11.39 -0.52 1.06e-25 Coronary artery disease; LIHC cis rs4800452 0.778 rs35699973 chr18:20726731 G/A cg26136497 chr18:20735537 CABLES1 -0.46 -6.14 -0.32 2.25e-9 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs7769051 1.000 rs9399041 chr6:133096233 T/G cg07930552 chr6:133119739 C6orf192 0.72 6.92 0.35 2.27e-11 Type 2 diabetes nephropathy; LIHC cis rs8060686 0.641 rs12445396 chr16:68155121 G/A cg09835421 chr16:68378352 PRMT7 -0.5 -5.78 -0.3 1.7e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs6542838 0.641 rs4850890 chr2:99535426 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.44 -7.23 -0.36 3.16e-12 Fear of minor pain; LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg11062466 chr8:58055876 NA 0.49 7.25 0.37 2.78e-12 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.49 0.42 6.51e-16 Platelet count; LIHC cis rs7107174 0.892 rs2090095 chr11:78034020 G/A cg02023728 chr11:77925099 USP35 0.45 8.77 0.43 8.35e-17 Testicular germ cell tumor; LIHC cis rs11229555 1.000 rs11603890 chr11:58402251 T/C cg15696309 chr11:58395628 NA -0.71 -8.75 -0.43 1.02e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4253772 0.591 rs6519993 chr22:46656479 A/G cg24881330 chr22:46731750 TRMU 0.54 5.82 0.3 1.39e-8 LDL cholesterol;Cholesterol, total; LIHC cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg21782813 chr7:2030301 MAD1L1 0.41 6.93 0.35 2.06e-11 Bipolar disorder and schizophrenia; LIHC cis rs1866706 0.896 rs4757950 chr11:12861523 G/A cg25843174 chr11:12811716 TEAD1 -0.31 -6.56 -0.33 1.96e-10 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg10360323 chr17:41437877 NA 0.41 6.1 0.31 2.9e-9 Menopause (age at onset); LIHC cis rs11690935 0.589 rs6729945 chr2:172864695 C/G cg13550731 chr2:172543902 DYNC1I2 0.44 6.69 0.34 9.32e-11 Schizophrenia; LIHC cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg13699009 chr12:122356056 WDR66 0.57 10.1 0.48 3.79e-21 Mean corpuscular volume; LIHC cis rs2832191 0.632 rs2246777 chr21:30309586 T/C cg24692254 chr21:30365293 RNF160 -0.83 -14.05 -0.6 1.04e-35 Dental caries; LIHC cis rs3857067 0.806 rs722486 chr4:95092315 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.55 -0.38 4.03e-13 QT interval; LIHC cis rs4853012 0.838 rs72911122 chr2:74344119 C/G cg19729930 chr2:74357872 NA 0.81 17.77 0.69 1.64e-50 Gestational age at birth (maternal effect); LIHC cis rs3820068 0.705 rs4646096 chr1:15820758 A/G cg17385448 chr1:15911702 AGMAT 0.37 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs933688 1.000 rs12655973 chr5:90736537 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.86 18.31 0.7 1.15e-52 Smoking behavior; LIHC cis rs10479542 0.929 rs7718673 chr5:178980009 C/T cg19723775 chr5:179050963 HNRNPH1 -0.38 -6.01 -0.31 4.78e-9 Lung cancer; LIHC cis rs1395 0.925 rs1659701 chr2:27414877 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 0.4 5.75 0.3 1.97e-8 Blood metabolite levels; LIHC cis rs17376456 0.877 rs12153788 chr5:93405437 A/G cg25358565 chr5:93447407 FAM172A 1.12 10.25 0.48 1.1e-21 Diabetic retinopathy; LIHC cis rs10744422 0.858 rs10773627 chr12:123311853 A/G cg18912006 chr12:123335444 HIP1R -0.57 -6.91 -0.35 2.31e-11 Schizophrenia; LIHC cis rs7116495 1.000 rs1939247 chr11:71740521 A/T cg26138937 chr11:71823887 C11orf51 -0.83 -8.27 -0.41 3e-15 Severe influenza A (H1N1) infection; LIHC cis rs10416265 0.527 rs7508599 chr19:33546512 A/T cg27124370 chr19:33622961 WDR88 0.56 7.95 0.4 2.67e-14 Bone properties (heel); LIHC cis rs9556958 0.527 rs9517313 chr13:99105892 C/G cg07423050 chr13:99094983 FARP1 0.55 10.21 0.48 1.49e-21 Educational attainment (years of education); LIHC cis rs9814567 1.000 rs1874883 chr3:134205071 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.2 -0.55 1.16e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1005277 0.579 rs2474575 chr10:38387901 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs17253792 0.555 rs17683626 chr14:56041112 G/T cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs9649213 0.593 rs2394854 chr7:98027306 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.81 -0.3 1.44e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs950169 0.922 rs8037078 chr15:84818871 A/G cg03959625 chr15:84868606 LOC388152 -0.44 -6.23 -0.32 1.39e-9 Schizophrenia; LIHC cis rs9467160 0.511 rs796984 chr6:24440600 T/A cg20631270 chr6:24437470 GPLD1 0.42 6.21 0.32 1.57e-9 Liver enzyme levels; LIHC cis rs6967414 0.579 rs11980762 chr7:6756878 G/A cg00387323 chr7:6746715 ZNF12 0.67 7.51 0.38 5.2e-13 Hematocrit;Hemoglobin concentration; LIHC cis rs7959452 0.590 rs11177643 chr12:69785712 T/G cg14784868 chr12:69753453 YEATS4 0.94 20.44 0.74 3.16e-61 Blood protein levels; LIHC cis rs35883536 0.647 rs34195036 chr1:101040429 C/A cg14515779 chr1:101123966 NA 0.45 6.37 0.33 6.24e-10 Monocyte count; LIHC cis rs1816752 0.870 rs9581029 chr13:24999285 C/A cg22771759 chr13:24902376 NA 0.32 6.56 0.33 2.05e-10 Obesity-related traits; LIHC cis rs7264396 0.563 rs2425116 chr20:34323553 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.47e-16 Total cholesterol levels; LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.8 0.39 7.59e-14 Height; LIHC cis rs11628318 0.713 rs1998419 chr14:103050397 C/G cg01864069 chr14:103024347 NA -0.57 -9.07 -0.44 9.18e-18 Platelet count; LIHC trans rs916888 0.821 rs199512 chr17:44857352 T/C cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg04607442 chr13:21872219 NA -0.54 -6.77 -0.34 5.54e-11 Hepatitis; LIHC cis rs60871478 1.000 rs4397290 chr7:828493 T/C cg05535760 chr7:792225 HEATR2 -0.76 -10.9 -0.51 6.15e-24 Cerebrospinal P-tau181p levels; LIHC cis rs1075232 1.000 rs12437749 chr15:31649888 C/T cg01030201 chr15:31746330 NA -0.78 -6.11 -0.31 2.66e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs1670533 1.000 rs11725984 chr4:1087338 C/T cg27284194 chr4:1044797 NA 0.61 8.99 0.44 1.72e-17 Recombination rate (females); LIHC cis rs2455799 0.613 rs2654654 chr3:15789242 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs11583043 0.958 rs11583674 chr1:101396560 C/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.3 0.32 8.96e-10 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4727027 0.901 rs1137432 chr7:148801658 C/T cg23583168 chr7:148888333 NA -0.7 -9.81 -0.47 3.57e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs9309711 0.623 rs4641971 chr2:3481857 A/C cg10845886 chr2:3471009 TTC15 0.47 8.69 0.43 1.54e-16 Neurofibrillary tangles; LIHC trans rs61931739 0.500 rs10844789 chr12:34202279 C/G cg26384229 chr12:38710491 ALG10B 0.55 7.06 0.36 9.12e-12 Morning vs. evening chronotype; LIHC cis rs9640161 0.742 rs2108851 chr7:150019634 T/C cg21361702 chr7:150065534 REPIN1 0.45 6.17 0.32 1.88e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs9790314 1.000 rs28515190 chr3:161028605 G/A cg03342759 chr3:160939853 NMD3 -0.71 -8.54 -0.42 4.38e-16 Morning vs. evening chronotype; LIHC cis rs240764 0.817 rs239201 chr6:101123993 T/A cg09795085 chr6:101329169 ASCC3 0.52 7.13 0.36 6.12e-12 Neuroticism; LIHC trans rs61931739 0.500 rs3934517 chr12:34451396 T/C cg26384229 chr12:38710491 ALG10B 0.64 8.06 0.4 1.31e-14 Morning vs. evening chronotype; LIHC cis rs992157 0.835 rs4674282 chr2:219144230 A/T cg20019365 chr2:219134978 PNKD;AAMP -0.76 -12.07 -0.55 3.59e-28 Colorectal cancer; LIHC cis rs17253792 0.545 rs12893610 chr14:56016347 C/T cg01858014 chr14:56050164 KTN1 -0.59 -5.8 -0.3 1.5e-8 Putamen volume; LIHC cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg25364880 chr3:44379878 C3orf23 0.49 6.97 0.35 1.63e-11 Depressive symptoms; LIHC cis rs7319311 0.899 rs9521729 chr13:111029970 G/A cg05272587 chr13:111038400 COL4A2 0.37 7.56 0.38 3.66e-13 Bipolar disorder and schizophrenia; LIHC cis rs1395 0.710 rs58965570 chr2:27481460 C/T cg23587288 chr2:27483067 SLC30A3 -0.35 -6.44 -0.33 3.99e-10 Blood metabolite levels; LIHC cis rs858239 0.537 rs2286272 chr7:23224367 T/C cg18081818 chr7:23246105 NA -0.4 -5.93 -0.31 7.36e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs17384381 0.859 rs35761966 chr1:85918357 G/A cg16011679 chr1:85725395 C1orf52 0.81 8.1 0.4 1e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs9443645 0.901 rs1354831 chr6:79613576 T/C cg05283184 chr6:79620031 NA -0.33 -5.76 -0.3 1.88e-8 Intelligence (multi-trait analysis); LIHC cis rs9640161 0.789 rs60283368 chr7:150023258 G/A cg21361702 chr7:150065534 REPIN1 0.46 6.24 0.32 1.31e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs4474465 1.000 rs11237500 chr11:78163636 G/A cg02023728 chr11:77925099 USP35 0.36 6.33 0.32 7.49e-10 Alzheimer's disease (survival time); LIHC cis rs7561273 0.586 rs12477718 chr2:24330539 A/G cg06627628 chr2:24431161 ITSN2 -0.44 -5.89 -0.3 9.14e-9 Quantitative traits; LIHC cis rs2404602 0.575 rs11072611 chr15:76947983 A/G cg23625390 chr15:77176239 SCAPER 0.45 7.19 0.36 4.2e-12 Blood metabolite levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11056748 chr11:66036038 RAB1B -0.46 -6.12 -0.31 2.56e-9 Bilirubin levels; LIHC cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.77 -11.36 -0.52 1.35e-25 Alzheimer's disease; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg27322371 chr3:150329392 SELT 0.51 6.2 0.32 1.66e-9 Mean platelet volume; LIHC cis rs1395 0.571 rs114507490 chr2:27527246 T/A cg22903471 chr2:27725779 GCKR -0.42 -6.07 -0.31 3.41e-9 Blood metabolite levels; LIHC cis rs7487075 0.619 rs7486495 chr12:46826336 A/G cg23829395 chr12:46796953 NA 0.35 6.13 0.31 2.45e-9 Itch intensity from mosquito bite; LIHC cis rs2153535 0.526 rs7748404 chr6:8472500 A/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg25193494 chr16:90016004 DEF8 0.42 5.72 0.3 2.33e-8 Skin colour saturation; LIHC cis rs1865760 0.929 rs2876693 chr6:25954434 C/G cg03264133 chr6:25882463 NA -0.4 -6.02 -0.31 4.42e-9 Height; LIHC cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.702 rs9929475 chr16:4540885 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 -0.45 -5.94 -0.31 7.05e-9 Schizophrenia; LIHC cis rs1801251 1.000 rs283486 chr2:233644223 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.5 0.53 4.2e-26 Coronary artery disease; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg04794120 chr7:48019205 HUS1 0.48 6.13 0.31 2.36e-9 Glycated hemoglobin levels; LIHC cis rs17253792 0.822 rs78143160 chr14:56150097 A/G cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC cis rs17401966 0.894 rs12141201 chr1:10454714 G/A cg19773385 chr1:10388646 KIF1B -0.38 -6.39 -0.33 5.47e-10 Hepatocellular carcinoma; LIHC cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs17401966 0.931 rs4846213 chr1:10399178 A/G cg19773385 chr1:10388646 KIF1B -0.39 -6.88 -0.35 2.85e-11 Hepatocellular carcinoma; LIHC cis rs4908768 0.906 rs74324642 chr1:8620172 A/C cg20416874 chr1:8611966 RERE 0.57 8.81 0.43 6.19e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4631830 0.863 rs4554834 chr10:51530146 A/C cg20129853 chr10:51489980 NA -0.41 -8.96 -0.44 2.13e-17 Prostate-specific antigen levels; LIHC cis rs1570884 0.536 rs1359541 chr13:50158939 A/G cg08779649 chr13:50194554 NA 0.34 6.12 0.31 2.59e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC trans rs12807809 0.588 rs3830078 chr11:124607535 G/A cg14028684 chr12:48723360 H1FNT 0.43 6.6 0.34 1.58e-10 Schizophrenia; LIHC cis rs2288073 0.801 rs6757275 chr2:24375230 A/G cg06627628 chr2:24431161 ITSN2 -0.52 -6.95 -0.35 1.85e-11 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs6598955 0.724 rs869683 chr1:26570993 T/A cg04990556 chr1:26633338 UBXN11 -0.62 -10.19 -0.48 1.79e-21 Obesity-related traits; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg26668828 chr6:292823 DUSP22 -0.62 -8.34 -0.41 1.83e-15 Menopause (age at onset); LIHC cis rs17376456 0.877 rs7734897 chr5:93305402 G/A cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg11764359 chr7:65958608 NA -0.56 -5.84 -0.3 1.21e-8 Diabetic kidney disease; LIHC cis rs6684514 1.000 rs12117947 chr1:156244058 A/T cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs61712019 0.679 rs35195056 chr2:77719199 T/C cg11252801 chr2:77748917 LRRTM4 0.56 7.73 0.39 1.2e-13 Schizophrenia; LIHC cis rs7618501 0.516 rs2856236 chr3:50161717 A/C cg24110177 chr3:50126178 RBM5 0.51 8.13 0.4 8.06e-15 Intelligence (multi-trait analysis); LIHC cis rs80282103 0.618 rs74117831 chr10:1145707 A/C cg08668510 chr10:1095578 IDI1 0.62 6.05 0.31 3.89e-9 Glomerular filtration rate (creatinine); LIHC cis rs2153535 0.580 rs7341382 chr6:8470549 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs1355223 0.902 rs1258464 chr11:34731496 C/T cg11058730 chr11:34937778 PDHX;APIP -0.42 -6.0 -0.31 5.05e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7762018 0.891 rs73242950 chr6:170144737 C/T cg19338460 chr6:170058176 WDR27 -0.38 -5.9 -0.3 8.61e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs507080 0.922 rs4589335 chr11:118539140 C/T cg04173919 chr11:118528438 PHLDB1 0.32 6.02 0.31 4.54e-9 Serum metabolite levels; LIHC cis rs10751667 0.666 rs7395402 chr11:950293 A/G cg10932868 chr11:921992 NA -0.39 -7.35 -0.37 1.51e-12 Alzheimer's disease (late onset); LIHC cis rs11792861 0.888 rs75543406 chr9:111816903 A/T cg13535736 chr9:111863775 C9orf5 -0.4 -5.99 -0.31 5.37e-9 Menarche (age at onset); LIHC cis rs703842 1.000 rs10783848 chr12:58196528 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.82 13.59 0.59 5.99e-34 Multiple sclerosis; LIHC trans rs35110281 0.712 rs1454648 chr21:45053815 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.12 0.31 2.53e-9 Mean corpuscular volume; LIHC cis rs208520 0.661 rs207111 chr6:66792513 C/T cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC cis rs12908161 0.959 rs35557864 chr15:85331629 A/G cg17507749 chr15:85114479 UBE2QP1 0.61 6.85 0.35 3.51e-11 Schizophrenia; LIHC cis rs35146811 0.555 rs1981550 chr7:99541952 G/A cg19636519 chr7:99541626 NA 0.31 6.17 0.32 1.93e-9 Coronary artery disease; LIHC cis rs2708977 0.965 rs12717781 chr2:97249142 G/A cg01950434 chr2:97203154 ARID5A 0.51 7.72 0.39 1.27e-13 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs10504229 0.679 rs2317991 chr8:58035080 C/T cg20607798 chr8:58055168 NA -0.47 -6.68 -0.34 9.9e-11 Developmental language disorder (linguistic errors); LIHC cis rs6089829 0.889 rs6062773 chr20:61663262 G/C cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC trans rs911555 0.755 rs11620897 chr14:103944861 T/G cg17675199 chr6:35436792 RPL10A 0.44 8.92 0.43 2.97e-17 Intelligence (multi-trait analysis); LIHC cis rs1775715 0.737 rs12256714 chr10:32216262 A/G cg14930904 chr10:32216787 ARHGAP12 -0.37 -6.55 -0.33 2.07e-10 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs11722228 0.549 rs41268389 chr4:10099277 G/A cg26043149 chr18:55253948 FECH 0.97 14.09 0.61 7.13e-36 Gout;Urate levels;Serum uric acid levels; LIHC cis rs7187994 0.848 rs12922556 chr16:84784290 C/T cg07647771 chr16:84786436 USP10 0.31 5.82 0.3 1.34e-8 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs10870270 0.956 rs10430618 chr10:133748996 C/T cg17892150 chr10:133769511 PPP2R2D -0.67 -12.41 -0.56 1.94e-29 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs12586317 0.547 rs28577270 chr14:35498443 G/A cg05294307 chr14:35346193 BAZ1A -0.5 -7.52 -0.38 4.91e-13 Psoriasis; LIHC cis rs9911578 0.967 rs11079368 chr17:57086473 C/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.95 -0.7 3.2e-51 Intelligence (multi-trait analysis); LIHC cis rs4746818 1.000 rs9299502 chr10:70876934 C/T cg11621586 chr10:70884670 VPS26A 0.86 13.59 0.59 6.18e-34 Left atrial antero-posterior diameter; LIHC cis rs739401 0.611 rs2301140 chr11:3022629 C/T cg25174290 chr11:3078921 CARS 0.58 8.36 0.41 1.65e-15 Longevity; LIHC cis rs7584330 0.737 rs7595979 chr2:238364492 G/T cg14458575 chr2:238380390 NA 0.37 5.75 0.3 1.95e-8 Prostate cancer; LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs12478296 0.748 rs10185596 chr2:243001029 C/A cg05760424 chr2:242988095 NA -0.4 -6.06 -0.31 3.69e-9 Obesity-related traits; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg19837214 chr12:133402551 GOLGA3 0.42 6.34 0.32 7.25e-10 Longevity; LIHC cis rs644148 1.000 rs644148 chr19:44970935 T/G cg15540054 chr19:45004280 ZNF180 -0.77 -11.42 -0.53 8.63e-26 Personality dimensions; LIHC cis rs9948 0.655 rs62156221 chr2:97410850 A/G cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7712401 0.755 rs1870560 chr5:122111210 G/C cg18764291 chr5:122110994 SNX2 0.35 6.02 0.31 4.4e-9 Mean platelet volume; LIHC cis rs7572733 0.534 rs700683 chr2:198712332 G/A cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs7208859 0.725 rs9915802 chr17:29173058 T/C cg13385521 chr17:29058706 SUZ12P 0.75 7.63 0.38 2.35e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8141529 0.732 rs5997408 chr22:29207915 G/A cg15103426 chr22:29168792 CCDC117 0.66 11.36 0.52 1.32e-25 Lymphocyte counts; LIHC cis rs933688 1.000 rs1895448 chr5:90743854 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 21.02 0.75 1.48e-63 Smoking behavior; LIHC cis rs3008870 1.000 rs2182143 chr1:67378936 T/C cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.29e-8 Lymphocyte percentage of white cells; LIHC cis rs9916302 0.851 rs11868029 chr17:37650304 A/G cg00129232 chr17:37814104 STARD3 -0.42 -6.81 -0.35 4.53e-11 Glomerular filtration rate (creatinine); LIHC cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg03452623 chr4:187889614 NA -0.35 -9.28 -0.45 2.03e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs17685 0.725 rs7807647 chr7:75628669 G/A cg04592579 chr7:75616294 TMEM120A -0.4 -6.96 -0.35 1.77e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9612 1.000 rs346545 chr19:44256386 T/C cg08581076 chr19:44259116 C19orf61 0.69 8.98 0.44 1.8e-17 Exhaled nitric oxide output; LIHC cis rs8058578 0.832 rs3812999 chr16:30773605 G/T cg00531865 chr16:30841666 NA -0.39 -5.93 -0.31 7.5e-9 Multiple myeloma; LIHC cis rs2455799 0.613 rs1532767 chr3:15733600 A/T cg12698662 chr3:15914712 MIR563 -0.35 -6.54 -0.33 2.24e-10 Mean platelet volume; LIHC trans rs66887589 0.837 rs7661498 chr4:120408108 T/C cg25214090 chr10:38739885 LOC399744 0.4 6.56 0.33 2e-10 Diastolic blood pressure; LIHC cis rs6456156 0.766 rs150112 chr6:167509878 C/T cg23791538 chr6:167370224 RNASET2 0.4 6.44 0.33 4.15e-10 Primary biliary cholangitis; LIHC cis rs11190604 1.000 rs2495732 chr10:102357780 T/C cg07080220 chr10:102295463 HIF1AN 0.57 7.41 0.37 1.01e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04180460 chr3:41240962 CTNNB1 0.48 7.43 0.37 9.05e-13 Pancreatic cancer; LIHC cis rs6442522 0.678 rs13059607 chr3:15507408 C/T cg16303742 chr3:15540471 COLQ 0.45 7.61 0.38 2.72e-13 Uric acid levels; LIHC cis rs829880 0.858 rs733180 chr12:98842588 C/T cg25150519 chr12:98850993 NA 0.61 9.29 0.45 1.79e-18 Colonoscopy-negative controls vs population controls; LIHC cis rs8016982 0.698 rs8021385 chr14:81704682 G/A cg01989461 chr14:81687754 GTF2A1 0.64 12.9 0.57 2.62e-31 Schizophrenia; LIHC cis rs2836974 0.644 rs11088472 chr21:40699376 A/C cg06238570 chr21:40685208 BRWD1 -0.51 -8.33 -0.41 1.99e-15 Cognitive function; LIHC cis rs58688157 0.960 rs702966 chr11:611919 C/G cg16486109 chr11:613632 IRF7 0.61 6.81 0.35 4.44e-11 Systemic lupus erythematosus; LIHC cis rs10504073 0.584 rs55908480 chr8:49923431 G/A cg00325661 chr8:49890786 NA 0.39 9.55 0.46 2.5e-19 Blood metabolite ratios; LIHC cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg15691649 chr6:25882328 NA -0.45 -5.98 -0.31 5.55e-9 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.931 rs11010083 chr10:35351531 C/G cg03585969 chr10:35415529 CREM 0.85 12.96 0.57 1.62e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs921968 0.607 rs2465100 chr2:219551044 A/T cg02985541 chr2:219472218 PLCD4 -0.39 -6.48 -0.33 3.18e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9303280 0.773 rs4795397 chr17:38023745 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.84 0.3 1.2e-8 Self-reported allergy; LIHC cis rs138857 0.515 rs9616373 chr22:50308597 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.81 -7.2 -0.36 3.77e-12 Mean platelet volume; LIHC cis rs10876993 0.890 rs799575 chr12:58069107 A/G cg15848620 chr12:58087721 OS9 -0.58 -8.0 -0.4 1.89e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs7568498 0.517 rs11678856 chr2:161925443 C/T cg16506815 chr2:162101123 NA -0.41 -6.25 -0.32 1.2e-9 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC cis rs2795502 0.882 rs2744093 chr10:43339243 A/G cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs1401999 0.966 rs2313216 chr3:183637251 C/T cg05044414 chr3:183734942 ABCC5 0.32 6.05 0.31 3.74e-9 Anterior chamber depth; LIHC cis rs7607369 0.714 rs1344643 chr2:219584975 G/C cg02985541 chr2:219472218 PLCD4 -0.36 -5.82 -0.3 1.36e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7312933 0.703 rs10880264 chr12:42586535 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.51 7.38 0.37 1.2e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7918232 0.574 rs10458708 chr10:27455605 C/T cg14442939 chr10:27389572 ANKRD26 0.81 14.58 0.62 8.91e-38 Breast cancer; LIHC cis rs2841277 0.770 rs10149193 chr14:105403474 C/T cg15352829 chr14:105391018 PLD4 -0.44 -9.38 -0.45 9.28e-19 Rheumatoid arthritis; LIHC cis rs600806 0.672 rs1144594 chr1:110029475 A/G cg08911820 chr1:110026001 ATXN7L2 -0.57 -7.0 -0.35 1.34e-11 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs2075371 0.966 rs1901204 chr7:133985896 A/G cg20476274 chr7:133979776 SLC35B4 0.73 12.0 0.54 6.1e-28 Mean platelet volume; LIHC cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg09222892 chr1:25734099 RHCE -0.45 -8.21 -0.41 4.48e-15 Erythrocyte sedimentation rate; LIHC cis rs9443189 0.570 rs7755068 chr6:76405700 A/G cg01950844 chr6:76311363 SENP6 0.87 10.9 0.51 6.08e-24 Prostate cancer; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg09033563 chr22:24373618 LOC391322 -0.45 -6.22 -0.32 1.46e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10744422 1.000 rs897386 chr12:123341289 A/C cg07706471 chr12:123319906 HIP1R -0.59 -7.84 -0.39 5.87e-14 Schizophrenia; LIHC cis rs1670533 1.000 rs2290411 chr4:1051077 T/C cg27284194 chr4:1044797 NA 0.6 9.02 0.44 1.36e-17 Recombination rate (females); LIHC cis rs2016586 0.802 rs5999977 chr22:36116097 T/G cg26342177 chr22:36113512 APOL5 -0.39 -6.71 -0.34 8.13e-11 Body mass index; LIHC cis rs9810089 0.814 rs696518 chr3:136120300 A/C cg21827317 chr3:136751795 NA 0.44 6.02 0.31 4.46e-9 Gestational age at birth (child effect); LIHC cis rs9902453 0.791 rs2628166 chr17:28113123 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.73 -12.06 -0.55 3.78e-28 Coffee consumption (cups per day); LIHC cis rs4805272 0.512 rs11879141 chr19:29320335 G/A cg04546413 chr19:29218101 NA 0.44 7.39 0.37 1.13e-12 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC trans rs4566357 0.615 rs10198214 chr2:227913314 A/C cg16088116 chr21:44841560 SIK1 -0.4 -6.23 -0.32 1.4e-9 Coronary artery disease; LIHC cis rs12540874 0.698 rs3823674 chr7:50571996 C/T cg18232548 chr7:50535776 DDC -0.4 -6.23 -0.32 1.35e-9 Systemic sclerosis; LIHC cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg15691649 chr6:25882328 NA -0.54 -7.75 -0.39 1.07e-13 Blood metabolite levels; LIHC cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg05590025 chr7:65112418 INTS4L2 -0.66 -7.2 -0.36 3.94e-12 Diabetic kidney disease; LIHC cis rs2281845 0.965 rs3738263 chr1:201083506 A/G cg01987224 chr1:201084466 NA -0.33 -6.14 -0.32 2.26e-9 Permanent tooth development; LIHC cis rs8017423 0.967 rs3825662 chr14:90723152 A/G cg04374321 chr14:90722782 PSMC1 0.76 15.09 0.63 8.84e-40 Mortality in heart failure; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11989942 chr17:80067146 CCDC57 0.41 6.3 0.32 9.06e-10 Immature fraction of reticulocytes; LIHC cis rs9427116 0.502 rs903323 chr1:154572228 A/G cg17218026 chr1:154582156 ADAR -0.35 -7.04 -0.36 1.06e-11 Blood protein levels; LIHC cis rs1873147 0.569 rs12593531 chr15:63309936 C/G cg05771511 chr15:63340396 TPM1 -0.45 -6.03 -0.31 4.14e-9 Orofacial clefts; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12828819 chr4:126236816 FAT4 0.45 6.12 0.31 2.55e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7552404 1.000 rs942270 chr1:76177332 G/A cg22875332 chr1:76189707 ACADM 0.47 6.71 0.34 8.15e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.65 9.21 0.45 3.28e-18 Lymphocyte counts; LIHC trans rs12144610 1.000 rs61806199 chr1:119450102 C/T cg17552093 chr17:79875985 SIRT7 0.65 6.11 0.31 2.79e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6424115 0.800 rs4649123 chr1:24197696 A/G cg04160030 chr1:24195659 FUCA1 -0.36 -5.88 -0.3 9.82e-9 Immature fraction of reticulocytes; LIHC cis rs2274273 0.743 rs13379159 chr14:55540801 C/T cg01864836 chr14:55583639 NA -0.38 -6.52 -0.33 2.49e-10 Protein biomarker; LIHC cis rs2370759 1.000 rs16933225 chr10:32599464 C/T cg01819863 chr10:32635814 EPC1 1.12 16.75 0.67 2.08e-46 Sexual dysfunction (female); LIHC cis rs250677 0.916 rs17109279 chr5:148416581 A/G cg18129178 chr5:148520854 ABLIM3 -0.47 -6.38 -0.33 5.75e-10 Breast cancer; LIHC cis rs910316 0.737 rs175072 chr14:75502827 T/C cg08847533 chr14:75593920 NEK9 -0.88 -18.19 -0.7 3.42e-52 Height; LIHC cis rs9790314 0.871 rs339114 chr3:161109220 C/T cg03342759 chr3:160939853 NMD3 0.64 7.87 0.39 4.67e-14 Morning vs. evening chronotype; LIHC cis rs867186 0.614 rs75848331 chr20:33424989 C/G cg08999081 chr20:33150536 PIGU 0.63 5.94 0.31 6.97e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs4970988 0.556 rs2280078 chr1:150600181 C/T cg15448220 chr1:150897856 SETDB1 -0.37 -5.83 -0.3 1.26e-8 Urate levels; LIHC cis rs4819052 0.851 rs2838832 chr21:46664904 A/G cg22633049 chr21:46681294 NA 0.36 6.18 0.32 1.84e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12477438 0.798 rs6542849 chr2:99578493 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.07 -14.82 -0.63 1.03e-38 Chronic sinus infection; LIHC cis rs2153535 0.580 rs9379215 chr6:8481225 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC trans rs2727020 0.553 rs61904166 chr11:49581461 T/C cg03929089 chr4:120376271 NA -0.88 -16.94 -0.68 3.45e-47 Coronary artery disease; LIHC cis rs4975616 0.869 rs452384 chr5:1330840 T/C cg07493874 chr5:1342172 CLPTM1L -0.68 -10.92 -0.51 5.23e-24 Lung cancer; LIHC cis rs9326778 0.520 rs4957817 chr5:108826387 C/T cg17395555 chr5:108820864 NA -0.35 -6.09 -0.31 3.11e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs6545883 0.783 rs7579651 chr2:61800279 C/G cg14146966 chr2:61757674 XPO1 0.46 7.78 0.39 8.84e-14 Tuberculosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17976829 chr10:131934431 GLRX3 0.41 6.96 0.35 1.78e-11 Cognitive function; LIHC cis rs6762 0.748 rs7929032 chr11:839078 G/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.64 -0.46 1.31e-19 Mean platelet volume; LIHC cis rs67311347 0.713 rs73073505 chr3:40310693 C/T cg02782426 chr3:40428986 ENTPD3 0.32 5.71 0.3 2.41e-8 Renal cell carcinoma; LIHC cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg06634786 chr22:41940651 POLR3H -0.7 -7.8 -0.39 7.8e-14 Vitiligo; LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg11766577 chr21:47581405 C21orf56 0.44 7.42 0.37 9.45e-13 Testicular germ cell tumor; LIHC cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.63 0.34 1.27e-10 Bipolar disorder; LIHC cis rs11098699 0.769 rs6812009 chr4:124215392 A/G cg09941581 chr4:124220074 SPATA5 0.33 6.66 0.34 1.1e-10 Mosquito bite size; LIHC cis rs2637266 1.000 rs11001830 chr10:78346396 G/A cg18941641 chr10:78392320 NA 0.29 6.22 0.32 1.43e-9 Pulmonary function; LIHC cis rs72772090 0.710 rs10515244 chr5:96078337 C/G cg17330273 chr5:96107758 CAST;ERAP1 -0.64 -7.26 -0.37 2.71e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs80282103 0.867 rs11250231 chr10:1082040 T/C cg20335179 chr10:1068567 C10orf110;IDI2 -0.52 -6.22 -0.32 1.45e-9 Glomerular filtration rate (creatinine); LIHC cis rs6952808 0.771 rs10275045 chr7:1920826 C/T cg02951883 chr7:2050386 MAD1L1 -0.57 -8.72 -0.43 1.23e-16 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs10845606 0.581 rs10772592 chr12:12835874 A/G cg09462578 chr12:12878428 APOLD1 -0.52 -7.68 -0.38 1.71e-13 Systemic lupus erythematosus; LIHC cis rs3793683 0.928 rs2148666 chr10:134553785 A/G cg26818010 chr10:134567672 INPP5A -0.6 -8.11 -0.4 9.37e-15 Migraine; LIHC cis rs3784262 0.967 rs12148907 chr15:58296450 T/A cg12031962 chr15:58353849 ALDH1A2 -0.35 -7.06 -0.36 9.6e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs10197940 0.662 rs4592848 chr2:152337822 G/A cg19508488 chr2:152266495 RIF1 0.59 8.22 0.41 4.39e-15 Lung cancer; LIHC cis rs7246657 0.943 rs7408563 chr19:37808585 G/C cg23950597 chr19:37808831 NA -0.55 -7.16 -0.36 5.05e-12 Coronary artery calcification; LIHC cis rs1976403 0.659 rs10799701 chr1:21820990 A/G cg20417195 chr1:21767127 NBPF3 0.36 5.77 0.3 1.74e-8 Liver enzyme levels (alkaline phosphatase); LIHC trans rs9388451 0.839 rs11154331 chr6:126111429 A/T cg05039488 chr6:79577232 IRAK1BP1 -0.51 -8.17 -0.4 5.99e-15 Brugada syndrome; LIHC trans rs2727020 0.595 rs10839281 chr11:49483373 A/C cg18944383 chr4:111397179 ENPEP 0.26 6.49 0.33 3.01e-10 Coronary artery disease; LIHC cis rs9733 0.519 rs7511673 chr1:150707636 A/T cg15448220 chr1:150897856 SETDB1 0.43 6.77 0.34 5.77e-11 Tonsillectomy; LIHC cis rs11122272 0.766 rs2808614 chr1:231550168 A/G cg06096015 chr1:231504339 EGLN1 -0.5 -9.35 -0.45 1.22e-18 Hemoglobin concentration; LIHC cis rs6714710 0.603 rs13023980 chr2:98502987 T/C cg26665480 chr2:98280029 ACTR1B 0.44 6.2 0.32 1.67e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg03806693 chr22:41940476 POLR3H 1.06 12.64 0.56 2.63e-30 Vitiligo; LIHC cis rs916888 0.821 rs199499 chr17:44865498 C/T cg15921436 chr17:44337874 NA 0.7 6.12 0.31 2.51e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6732160 0.691 rs13432787 chr2:73430234 T/C cg24220031 chr2:73402428 NA -0.28 -6.01 -0.31 4.65e-9 Intelligence (multi-trait analysis); LIHC cis rs1003719 0.680 rs2835620 chr21:38505581 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.46e-25 Eye color traits; LIHC trans rs2243480 0.803 rs34004500 chr7:65312178 A/T cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs7395581 1.000 rs830085 chr11:47251199 G/A cg25783544 chr11:47291846 MADD -0.47 -6.8 -0.35 4.72e-11 HDL cholesterol; LIHC cis rs360798 0.532 rs189671 chr2:62959308 T/A cg17519650 chr2:63277830 OTX1 -0.53 -8.19 -0.4 5.38e-15 Coronary artery disease; LIHC cis rs7089973 0.604 rs2420065 chr10:116583753 A/G cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.11 0.52 1.04e-24 Platelet count; LIHC cis rs6424115 1.000 rs974698 chr1:24132785 C/T cg10978503 chr1:24200527 CNR2 0.37 8.82 0.43 6.15e-17 Immature fraction of reticulocytes; LIHC cis rs1075232 1.000 rs72722847 chr15:31682346 C/T cg01030201 chr15:31746330 NA -0.81 -6.25 -0.32 1.21e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs10861342 1.000 rs11112398 chr12:105572967 A/G cg23923672 chr12:105501055 KIAA1033 0.63 7.66 0.38 1.94e-13 IgG glycosylation; LIHC cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg07061783 chr6:25882402 NA 0.69 8.76 0.43 9.54e-17 Blood metabolite levels; LIHC cis rs13343954 0.825 rs11084698 chr19:33534174 A/G cg27124370 chr19:33622961 WDR88 0.42 5.73 0.3 2.21e-8 Colorectal cancer; LIHC cis rs34779708 0.931 rs11593858 chr10:35381373 G/A cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9372253 1.000 rs9384740 chr6:110716207 G/A cg19196401 chr6:110721138 DDO -0.32 -6.38 -0.33 5.82e-10 Platelet distribution width; LIHC cis rs11098499 0.865 rs9996417 chr4:120295862 T/C cg09307838 chr4:120376055 NA 0.76 11.49 0.53 4.66e-26 Corneal astigmatism; LIHC cis rs2071426 0.959 rs35394919 chr10:96810972 C/T cg09036531 chr10:96991505 NA -0.5 -6.0 -0.31 5.08e-9 Blood metabolite levels; LIHC cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg03452623 chr4:187889614 NA -0.32 -8.36 -0.41 1.55e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6456156 0.586 rs13208636 chr6:167461965 T/G cg23791538 chr6:167370224 RNASET2 -0.53 -8.64 -0.42 2.18e-16 Primary biliary cholangitis; LIHC cis rs6089584 0.927 rs3787427 chr20:60579789 T/C cg12751644 chr20:60527061 NA -0.37 -6.14 -0.32 2.31e-9 Body mass index; LIHC cis rs7552404 1.000 rs441109 chr1:76120430 T/G cg22875332 chr1:76189707 ACADM -0.48 -6.95 -0.35 1.82e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg00825309 chr19:58991885 ZNF446 -0.53 -8.36 -0.41 1.62e-15 Uric acid clearance; LIHC cis rs6582630 0.576 rs4882258 chr12:38453686 C/T cg26384229 chr12:38710491 ALG10B -0.45 -5.81 -0.3 1.43e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.65 -10.7 -0.5 3.12e-23 Menarche (age at onset); LIHC cis rs2637266 0.967 rs7477607 chr10:78358768 G/T cg18941641 chr10:78392320 NA 0.27 5.71 0.3 2.42e-8 Pulmonary function; LIHC cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.95 8.45 0.42 8.22e-16 Platelet count; LIHC cis rs11098499 0.863 rs11947234 chr4:120474859 A/G cg09307838 chr4:120376055 NA 0.75 11.44 0.53 6.88e-26 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.59 0.56 4.01e-30 Prudent dietary pattern; LIHC cis rs9372253 0.967 rs9400379 chr6:110713783 A/G cg00083206 chr6:110721305 DDO -0.34 -6.69 -0.34 9.06e-11 Platelet distribution width; LIHC cis rs3784262 1.000 rs11071356 chr15:58240518 T/G cg12031962 chr15:58353849 ALDH1A2 -0.31 -5.99 -0.31 5.17e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6684514 1.000 rs12027103 chr1:156244856 G/A cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg12292205 chr6:26970375 C6orf41 -0.41 -7.06 -0.36 9.22e-12 Schizophrenia; LIHC cis rs6430585 0.591 rs75223002 chr2:136525309 G/T cg07169764 chr2:136633963 MCM6 1.15 16.41 0.66 4.97e-45 Corneal structure; LIHC cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.37 0.45 1e-18 Bipolar disorder; LIHC cis rs3749237 0.595 rs7637999 chr3:49535115 C/T cg07636037 chr3:49044803 WDR6 0.56 8.46 0.42 7.75e-16 Resting heart rate; LIHC cis rs2075371 0.933 rs1833474 chr7:133958240 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.68e-14 Mean platelet volume; LIHC cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.87 0.3 1.05e-8 Menopause (age at onset); LIHC cis rs4561483 0.801 rs33620 chr16:12008546 C/G cg08843971 chr16:11963173 GSPT1 -0.43 -8.47 -0.42 7.19e-16 Testicular germ cell tumor; LIHC cis rs4759375 1.000 rs10444439 chr12:123766437 A/G cg00376283 chr12:123451042 ABCB9 -0.5 -6.35 -0.32 6.82e-10 HDL cholesterol; LIHC cis rs34779708 0.733 rs16935945 chr10:35540320 A/C cg03585969 chr10:35415529 CREM 0.76 11.03 0.51 2.14e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg18538332 chr22:24372958 LOC391322 -0.67 -9.99 -0.48 8.92e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3008870 1.000 rs2985817 chr1:67398607 G/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs970821 0.667 rs1030590 chr8:124754410 A/G cg00283535 chr8:124749564 ANXA13 0.46 8.6 0.42 2.99e-16 Breast cancer; LIHC cis rs7903847 0.692 rs7900255 chr10:99157575 G/A cg20016023 chr10:99160130 RRP12 -0.43 -6.87 -0.35 3.02e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs7739232 0.920 rs6941645 chr6:53515130 A/G cg00536792 chr6:53530503 KLHL31 -0.9 -6.71 -0.34 8.33e-11 Hip circumference adjusted for BMI; LIHC cis rs1823913 1.000 rs11681777 chr2:192121467 G/A cg12404831 chr2:192114017 MYO1B -0.33 -6.5 -0.33 2.9e-10 Obesity-related traits; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg06656553 chr16:89960601 TCF25 -0.46 -5.91 -0.3 8.17e-9 Skin colour saturation; LIHC cis rs7772486 0.875 rs2814872 chr6:146310234 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.43 0.53 7.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs35955747 0.902 rs12166373 chr22:31700508 A/G cg22777020 chr22:31556080 RNF185 -0.5 -5.89 -0.3 9.31e-9 Neutrophil count;Sum basophil neutrophil counts; LIHC cis rs9324022 0.929 rs17099617 chr14:101170488 A/G cg18089426 chr14:101175970 NA 0.46 5.91 0.3 8.05e-9 Plateletcrit; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg07725925 chr16:89976287 TCF25 0.45 6.16 0.32 2e-9 Skin colour saturation; LIHC trans rs916888 0.821 rs199505 chr17:44859410 A/G cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs765787 0.505 rs11630884 chr15:45532246 C/T cg25801113 chr15:45476975 SHF 0.38 6.55 0.33 2.1e-10 Uric acid levels; LIHC cis rs10751667 0.666 rs7483273 chr11:951127 T/C cg06064525 chr11:970664 AP2A2 -0.57 -15.0 -0.63 1.96e-39 Alzheimer's disease (late onset); LIHC cis rs4589502 0.502 rs2169460 chr15:67197240 A/G cg12317470 chr15:67143691 NA -0.66 -8.75 -0.43 1.01e-16 Lung cancer (smoking interaction); LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg24209194 chr3:40518798 ZNF619 0.63 9.57 0.46 2.18e-19 Renal cell carcinoma; LIHC cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.96 0.31 6.17e-9 Bipolar disorder; LIHC cis rs28735056 0.967 rs623546 chr18:77595228 C/T cg20368463 chr18:77673604 PQLC1 -0.38 -6.7 -0.34 8.47e-11 Schizophrenia; LIHC cis rs8062405 0.723 rs62031562 chr16:28609329 A/T cg16576597 chr16:28551801 NUPR1 0.48 7.31 0.37 1.87e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs644148 0.730 rs2117383 chr19:44978298 A/C cg15540054 chr19:45004280 ZNF180 0.69 9.46 0.46 5.05e-19 Personality dimensions; LIHC cis rs10503871 0.545 rs6991816 chr8:30487344 C/T cg26383811 chr8:30366931 RBPMS -0.4 -6.44 -0.33 4.04e-10 Metabolite levels (X-11787); LIHC cis rs4561483 0.801 rs33660 chr16:11961858 A/G cg08843971 chr16:11963173 GSPT1 -0.43 -8.72 -0.43 1.23e-16 Testicular germ cell tumor; LIHC cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg06697600 chr4:7070879 GRPEL1 -0.63 -10.27 -0.49 9.26e-22 Monocyte percentage of white cells; LIHC cis rs1843834 0.505 rs940317 chr2:225358118 C/T cg12698349 chr2:225449008 CUL3 0.69 10.71 0.5 2.95e-23 IgE levels in asthmatics (D.p. specific); LIHC cis rs9430161 0.579 rs7542354 chr1:11040385 G/A cg27631724 chr1:11040367 C1orf127 0.38 7.75 0.39 1.05e-13 Ewing sarcoma; LIHC cis rs9814567 1.000 rs7374158 chr3:134270156 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6570726 0.620 rs12201226 chr6:145913419 A/T cg13319975 chr6:146136371 FBXO30 -0.59 -8.88 -0.43 3.95e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs950169 0.887 rs12903946 chr15:84954430 T/C cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.12e-11 Schizophrenia; LIHC cis rs6499255 0.857 rs8060588 chr16:69656500 A/G cg15192750 chr16:69999425 NA 0.46 7.03 0.36 1.12e-11 IgE levels; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg09455208 chr3:40491958 NA -0.37 -7.89 -0.39 4.04e-14 Renal cell carcinoma; LIHC cis rs6089829 0.926 rs1060491 chr20:61665817 C/A cg08564027 chr20:61660810 NA -0.41 -7.69 -0.38 1.53e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs9303401 0.614 rs34678056 chr17:57177549 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.42 0.56 1.76e-29 Cognitive test performance; LIHC cis rs711245 0.699 rs3770818 chr2:36769497 T/G cg10546459 chr2:36825355 FEZ2 0.52 6.31 0.32 8.86e-10 Height; LIHC cis rs55702914 0.904 rs68062151 chr2:198230190 C/T cg10820045 chr2:198174542 NA 0.41 6.1 0.31 2.83e-9 Major depression and alcohol dependence; LIHC cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.4 -6.0 -0.31 5.01e-9 Menarche (age at onset); LIHC trans rs7395662 0.571 rs12421145 chr11:48624725 C/A cg03929089 chr4:120376271 NA -0.4 -6.08 -0.31 3.14e-9 HDL cholesterol; LIHC cis rs67311347 0.869 rs6790495 chr3:40366770 C/T cg09455208 chr3:40491958 NA 0.33 6.43 0.33 4.32e-10 Renal cell carcinoma; LIHC cis rs9682041 0.867 rs6444925 chr3:170123358 G/T cg11886554 chr3:170076028 SKIL 1.08 7.4 0.37 1.08e-12 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs561341 1.000 rs8070262 chr17:30262467 A/G cg13647721 chr17:30228624 UTP6 0.67 6.62 0.34 1.38e-10 Hip circumference adjusted for BMI; LIHC cis rs1801251 0.896 rs921054 chr2:233694673 G/A cg25237894 chr2:233734115 C2orf82 -0.54 -10.0 -0.48 8.1899999999999992e-21 Coronary artery disease; LIHC cis rs2070488 0.775 rs1073506 chr3:38566235 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.69 -11.3 -0.52 2.33e-25 Electrocardiographic conduction measures; LIHC cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg16606324 chr3:10149918 C3orf24 0.54 5.77 0.3 1.79e-8 Alzheimer's disease; LIHC cis rs3768617 0.510 rs4491025 chr1:183065183 C/T ch.1.3577855R chr1:183094577 LAMC1 0.63 10.92 0.51 5.31e-24 Fuchs's corneal dystrophy; LIHC cis rs611744 0.647 rs2594357 chr8:109255989 A/G cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg13699009 chr12:122356056 WDR66 0.61 9.2 0.45 3.55e-18 Mean corpuscular volume; LIHC trans rs9926296 0.581 rs1108064 chr16:89894150 G/C cg13698153 chr12:118541722 VSIG10 0.6 6.36 0.33 6.59e-10 Vitiligo; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.55 -7.89 -0.39 4.02e-14 Lymphocyte counts; LIHC cis rs9790314 1.000 rs336591 chr3:161078080 A/G cg04691961 chr3:161091175 C3orf57 -0.46 -7.34 -0.37 1.54e-12 Morning vs. evening chronotype; LIHC cis rs9303401 0.592 rs12936771 chr17:56725052 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs9303401 0.538 rs10515155 chr17:56481944 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.85 11.44 0.53 6.77e-26 Cognitive test performance; LIHC cis rs7246657 0.943 rs10414904 chr19:37830088 G/A cg23950597 chr19:37808831 NA -0.44 -5.97 -0.31 5.93e-9 Coronary artery calcification; LIHC cis rs4805272 0.626 rs12608533 chr19:29331405 C/G cg14983838 chr19:29218262 NA 0.39 5.91 0.3 8.16e-9 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs9303401 0.659 rs714959 chr17:56628601 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.08 0.58 5.75e-32 Cognitive test performance; LIHC cis rs10751667 0.714 rs7933889 chr11:972270 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs9549367 0.826 rs9549713 chr13:113905308 G/T cg00898013 chr13:113819073 PROZ -0.42 -7.18 -0.36 4.24e-12 Platelet distribution width; LIHC cis rs5769765 0.862 rs9616385 chr22:50313124 C/T cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg07341007 chr3:195489909 MUC4 0.45 7.92 0.39 3.37e-14 Lung disease severity in cystic fibrosis; LIHC cis rs875971 0.660 rs10215132 chr7:66054406 C/A cg14393609 chr7:65229607 NA -0.38 -6.08 -0.31 3.24e-9 Aortic root size; LIHC cis rs4713118 0.513 rs156738 chr6:28014025 G/C cg16479474 chr6:28041457 NA 0.39 6.38 0.33 5.78e-10 Parkinson's disease; LIHC trans rs1488564 1.000 rs1488564 chr3:173453868 A/G cg04693399 chr19:4909447 UHRF1 -0.43 -6.12 -0.31 2.5e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs1704198 1.000 rs12401447 chr1:213897230 T/C cg02442787 chr4:139230014 NA 0.42 6.37 0.33 6.07e-10 Obesity; LIHC cis rs17685 0.753 rs1637051 chr7:75730659 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.17 -0.32 1.97e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2839627 0.513 rs7282879 chr21:44286525 C/T cg03543861 chr21:44258195 NA 0.48 7.68 0.38 1.74e-13 Information processing speed; LIHC cis rs6558530 0.626 rs6558524 chr8:1702512 T/G cg24391279 chr8:1708526 NA -0.35 -5.85 -0.3 1.14e-8 Systolic blood pressure; LIHC cis rs72781680 0.898 rs72780118 chr2:23994431 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.62 0.38 2.45e-13 Lymphocyte counts; LIHC cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg13271783 chr10:134563150 INPP5A -0.59 -7.11 -0.36 6.89e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9341808 0.905 rs9343977 chr6:80967001 C/T cg08355045 chr6:80787529 NA 0.29 5.74 0.3 2.05e-8 Sitting height ratio; LIHC cis rs7100689 0.784 rs10749578 chr10:82139115 A/G cg00277334 chr10:82204260 NA 0.52 6.59 0.34 1.69e-10 Post bronchodilator FEV1; LIHC cis rs9303401 0.659 rs12946397 chr17:56769979 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs7000551 0.751 rs2443494 chr8:22372262 C/G cg12081754 chr8:22256438 SLC39A14 0.41 6.54 0.33 2.22e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs311392 0.867 rs364484 chr8:55093492 G/T cg11783602 chr8:55087084 NA -0.31 -6.2 -0.32 1.66e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs2228479 0.850 rs11076623 chr16:89844120 G/T cg00800038 chr16:89945340 TCF25 -0.64 -9.34 -0.45 1.31e-18 Skin colour saturation; LIHC cis rs2204008 0.666 rs67792345 chr12:38204698 T/C cg26384229 chr12:38710491 ALG10B 0.88 10.83 0.51 1.1e-23 Bladder cancer; LIHC cis rs13108904 0.905 rs34490749 chr4:1217981 A/G cg13395646 chr4:1353034 KIAA1530 -0.44 -6.42 -0.33 4.54e-10 Obesity-related traits; LIHC cis rs7635838 0.617 rs2594971 chr3:11313910 G/A cg00170343 chr3:11313890 ATG7 0.62 10.53 0.49 1.21e-22 HDL cholesterol; LIHC cis rs61041384 0.661 rs75338281 chr12:123507484 G/A cg00376283 chr12:123451042 ABCB9 -0.6 -5.71 -0.3 2.4e-8 Schizophrenia; LIHC cis rs67460515 0.563 rs11713441 chr3:160906855 T/C cg17135325 chr3:160939158 NMD3 0.61 9.01 0.44 1.52e-17 Parkinson's disease; LIHC cis rs11690935 0.632 rs35854151 chr2:172657439 G/A cg13550731 chr2:172543902 DYNC1I2 0.62 11.12 0.52 9.86e-25 Schizophrenia; LIHC cis rs743757 1.000 rs2236984 chr3:50495487 A/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.49 7.73 0.39 1.25e-13 Diastolic blood pressure; LIHC cis rs6728642 0.908 rs6576996 chr2:97623312 T/C cg26665480 chr2:98280029 ACTR1B -0.57 -6.43 -0.33 4.29e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs17685 0.753 rs12531559 chr7:75631697 C/T cg04592579 chr7:75616294 TMEM120A -0.4 -6.94 -0.35 1.93e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7617773 0.817 rs11720622 chr3:48246679 G/A cg11946769 chr3:48343235 NME6 0.65 8.92 0.43 2.87e-17 Coronary artery disease; LIHC cis rs16866061 1.000 rs72974205 chr2:225408468 C/T cg12698349 chr2:225449008 CUL3 0.81 14.11 0.61 5.84e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs17666538 0.585 rs336444 chr8:633123 C/G cg07234876 chr8:600039 NA -0.63 -6.38 -0.33 5.68e-10 IgG glycosylation; LIHC cis rs875971 0.545 rs1267814 chr7:66044409 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.84 -0.35 3.75e-11 Aortic root size; LIHC cis rs7572733 0.515 rs6752458 chr2:198835106 G/T cg00792783 chr2:198669748 PLCL1 0.45 6.6 0.34 1.52e-10 Dermatomyositis; LIHC cis rs12586317 0.548 rs12590678 chr14:35602956 C/T cg05294307 chr14:35346193 BAZ1A -0.47 -6.94 -0.35 1.94e-11 Psoriasis; LIHC cis rs769267 0.896 rs7250893 chr19:19625547 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.0 0.31 5.11e-9 Tonsillectomy; LIHC cis rs734999 0.566 rs6424092 chr1:2532899 C/A cg18854424 chr1:2615690 NA -0.32 -7.07 -0.36 8.7e-12 Ulcerative colitis; LIHC cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg06636001 chr8:8085503 FLJ10661 0.6 9.98 0.48 9.14e-21 Systolic blood pressure; LIHC cis rs7412746 0.658 rs10305714 chr1:150800655 C/T cg18016565 chr1:150552671 MCL1 -0.49 -9.58 -0.46 2.09e-19 Melanoma; LIHC cis rs12220238 0.915 rs11001021 chr10:76139657 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs208520 0.874 rs208517 chr6:66947040 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.69 -7.61 -0.38 2.77e-13 Exhaled nitric oxide output; LIHC cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg12756686 chr19:29218302 NA 0.43 6.63 0.34 1.34e-10 Methadone dose in opioid dependence; LIHC cis rs311392 0.833 rs6473917 chr8:55090430 A/G cg20636351 chr8:55087400 NA -0.38 -7.77 -0.39 9.54e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs2228479 0.850 rs1800331 chr16:89858417 C/A cg19635926 chr16:89946313 TCF25 0.54 6.76 0.34 5.85e-11 Skin colour saturation; LIHC cis rs10870270 1.000 rs10430617 chr10:133748889 T/C cg17892150 chr10:133769511 PPP2R2D -0.67 -12.41 -0.56 1.94e-29 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs3749237 0.964 rs34522271 chr3:49808517 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.65 9.87 0.47 2.23e-20 Resting heart rate; LIHC cis rs7666738 0.830 rs2865990 chr4:99067399 C/A cg05340658 chr4:99064831 C4orf37 0.71 13.15 0.58 2.99e-32 Colonoscopy-negative controls vs population controls; LIHC trans rs3960554 0.808 rs111714534 chr7:75748896 C/T cg19862616 chr7:65841803 NCRNA00174 0.59 8.09 0.4 1.07e-14 Eotaxin levels; LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg18306943 chr3:40428807 ENTPD3 0.43 7.53 0.38 4.6e-13 Renal cell carcinoma; LIHC trans rs7618501 0.669 rs3774758 chr3:49938227 C/G cg21659725 chr3:3221576 CRBN 0.73 11.46 0.53 6.07e-26 Intelligence (multi-trait analysis); LIHC cis rs2839627 0.598 rs9975526 chr21:44266573 T/A cg03543861 chr21:44258195 NA 0.49 7.86 0.39 5.21e-14 Information processing speed; LIHC cis rs11098699 0.769 rs11726870 chr4:124229175 A/G cg09941581 chr4:124220074 SPATA5 0.33 6.59 0.34 1.68e-10 Mosquito bite size; LIHC cis rs7937840 0.562 rs1047739 chr11:61919693 C/T cg01969543 chr11:61895209 INCENP -0.49 -6.29 -0.32 9.81e-10 Breast cancer; LIHC cis rs7818382 0.967 rs7812465 chr8:96050557 C/T cg09323728 chr8:95962352 TP53INP1 0.29 6.78 0.34 5.24e-11 Alzheimer's disease (late onset); LIHC cis rs72781680 0.898 rs72786286 chr2:24074659 T/A cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs11122272 0.735 rs2572249 chr1:231514829 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.4 0.45 7.89e-19 Hemoglobin concentration; LIHC cis rs523522 0.962 rs55848094 chr12:120966659 G/A cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC cis rs4638749 0.677 rs12712018 chr2:108853505 A/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.48 -0.33 3.22e-10 Blood pressure; LIHC cis rs926392 0.965 rs6129167 chr20:37689228 C/T cg16355469 chr20:37678765 NA -0.37 -6.01 -0.31 4.63e-9 Dialysis-related mortality; LIHC cis rs6545883 0.965 rs7591345 chr2:61729641 T/A cg14146966 chr2:61757674 XPO1 0.49 8.62 0.42 2.6e-16 Tuberculosis; LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2427308 0.643 rs477859 chr20:60937597 A/G cg03945807 chr20:60948434 NA -0.45 -6.05 -0.31 3.75e-9 Colorectal cancer; LIHC trans rs116095464 0.558 rs56342538 chr5:225796 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11564483 chr6:37401398 FTSJD2 0.5 6.81 0.35 4.36e-11 Lung function (FEV1/FVC); LIHC cis rs7116495 0.737 rs1791451 chr11:71570993 G/T cg26138937 chr11:71823887 C11orf51 0.7 6.64 0.34 1.25e-10 Severe influenza A (H1N1) infection; LIHC cis rs8016982 0.963 rs7149672 chr14:81657336 A/G cg01989461 chr14:81687754 GTF2A1 0.56 10.97 0.51 3.39e-24 Schizophrenia; LIHC cis rs2645694 0.626 rs2703126 chr4:77819842 T/C cg06046430 chr4:77819534 ANKRD56 0.49 6.48 0.33 3.18e-10 Emphysema distribution in smoking; LIHC cis rs61712019 0.679 rs55777925 chr2:77726204 C/G cg11252801 chr2:77748917 LRRTM4 0.55 7.83 0.39 6.25e-14 Schizophrenia; LIHC cis rs34779708 0.966 rs34296409 chr10:35404613 C/G cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg09060608 chr5:178986726 RUFY1 -0.39 -6.06 -0.31 3.59e-9 Lung cancer; LIHC cis rs7833790 0.724 rs12676336 chr8:82771008 C/T cg27398817 chr8:82754497 SNX16 0.32 5.76 0.3 1.9e-8 Diastolic blood pressure; LIHC cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg18867708 chr6:26865862 GUSBL1 -0.55 -8.49 -0.42 6.47e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs763121 0.962 rs909564 chr22:39126508 A/G cg06022373 chr22:39101656 GTPBP1 0.62 11.76 0.54 4.76e-27 Menopause (age at onset); LIHC cis rs3809863 0.602 rs7225700 chr17:45391804 T/C cg08085267 chr17:45401833 C17orf57 -0.64 -9.98 -0.48 9.06e-21 Glaucoma (primary open-angle); LIHC cis rs7617773 1.000 rs9832957 chr3:48185266 A/G cg11946769 chr3:48343235 NME6 -0.66 -8.54 -0.42 4.59e-16 Coronary artery disease; LIHC cis rs2108225 0.837 rs6959729 chr7:107446180 A/C cg18560240 chr7:107437656 SLC26A3 -0.42 -6.64 -0.34 1.23e-10 Ulcerative colitis; LIHC cis rs9814567 0.752 rs13075253 chr3:134329600 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.6 9.74 0.47 6.02e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs644799 0.965 rs607039 chr11:95547086 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs561341 0.663 rs72821936 chr17:30224068 C/G cg20587970 chr11:113659929 NA -0.49 -6.3 -0.32 9.31e-10 Hip circumference adjusted for BMI; LIHC cis rs4631830 0.900 rs11006274 chr10:51540291 C/T cg20129853 chr10:51489980 NA 0.4 8.92 0.43 2.9e-17 Prostate-specific antigen levels; LIHC trans rs1875517 0.510 rs11721241 chr3:117329656 A/C cg23648015 chr19:49519116 RUVBL2 0.36 6.39 0.33 5.42e-10 Waist circumference; LIHC trans rs2579103 0.626 rs2579099 chr12:90687355 C/T cg02782426 chr3:40428986 ENTPD3 0.36 6.09 0.31 2.96e-9 Body mass index; LIHC cis rs7911264 0.967 rs2488087 chr10:94446041 G/A cg25506282 chr10:94462361 NA -0.43 -7.43 -0.37 8.96e-13 Inflammatory bowel disease; LIHC cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg16145915 chr7:1198662 ZFAND2A -0.34 -8.39 -0.41 1.3e-15 Longevity;Endometriosis; LIHC cis rs9457247 0.565 rs12178491 chr6:167512474 C/T cg07741184 chr6:167504864 NA 0.35 8.43 0.41 9.93e-16 Crohn's disease; LIHC cis rs3806843 1.000 rs10053586 chr5:140210760 T/C cg26395211 chr5:140044315 WDR55 -0.43 -6.43 -0.33 4.25e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7312933 0.703 rs10880268 chr12:42599122 C/T cg17420585 chr12:42539391 GXYLT1 -0.37 -5.91 -0.3 8.32e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7818688 0.697 rs11780130 chr8:95976083 A/G cg16049864 chr8:95962084 TP53INP1 0.61 6.64 0.34 1.24e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs17270561 0.525 rs10484432 chr6:26008876 G/A cg17691542 chr6:26056736 HIST1H1C 1.02 12.86 0.57 3.73e-31 Iron status biomarkers; LIHC cis rs7903847 0.642 rs7084654 chr10:99135262 G/A cg20016023 chr10:99160130 RRP12 -0.41 -6.48 -0.33 3.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9303280 0.747 rs1453559 chr17:38020419 T/C cg11212589 chr17:38028394 ZPBP2 0.35 7.15 0.36 5.17e-12 Self-reported allergy; LIHC cis rs2439831 0.850 rs7174208 chr15:44052682 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.5 0.42 6.09e-16 Lung cancer in ever smokers; LIHC trans rs7618501 0.633 rs13060128 chr3:50025028 A/G cg21659725 chr3:3221576 CRBN 0.67 10.88 0.51 7.31e-24 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.739 rs66539935 chr3:47025327 C/T cg27129171 chr3:47204927 SETD2 -0.57 -9.39 -0.45 8.81e-19 Colorectal cancer; LIHC cis rs7959452 0.535 rs7308481 chr12:69659299 A/G cg22834771 chr12:69754056 YEATS4 -0.5 -8.48 -0.42 6.72e-16 Blood protein levels; LIHC cis rs67460515 0.500 rs9822435 chr3:160748068 A/T cg03342759 chr3:160939853 NMD3 -0.51 -6.94 -0.35 2e-11 Parkinson's disease; LIHC cis rs4555082 0.957 rs2816627 chr14:105736109 A/G cg13114125 chr14:105738426 BRF1 -0.69 -9.33 -0.45 1.41e-18 Mean platelet volume;Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17981554 chr6:149969568 NA 0.48 6.22 0.32 1.43e-9 Lung function (FEV1/FVC); LIHC cis rs4253772 0.591 rs6008362 chr22:46652737 G/A cg09491104 chr22:46646882 C22orf40 -0.7 -8.18 -0.4 5.49e-15 LDL cholesterol;Cholesterol, total; LIHC cis rs12586317 0.545 rs58342373 chr14:35395269 T/C cg16230307 chr14:35515116 FAM177A1 0.68 10.8 0.5 1.41e-23 Psoriasis; LIHC cis rs1559088 0.901 rs7249983 chr19:33598851 C/A cg17764715 chr19:33622953 WDR88 0.44 6.19 0.32 1.72e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg11890956 chr21:40555474 PSMG1 1.06 15.16 0.63 4.63e-40 Cognitive function; LIHC cis rs2637266 1.000 rs12260492 chr10:78365242 C/A cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.17e-8 Pulmonary function; LIHC cis rs11786130 1.000 rs10956403 chr8:129007207 A/G cg01765152 chr8:129005526 PVT1 -0.3 -6.39 -0.33 5.32e-10 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg08392591 chr16:89556376 ANKRD11 0.53 8.23 0.41 3.86e-15 Multiple myeloma (IgH translocation); LIHC cis rs950169 0.922 rs12912934 chr15:85114447 C/T cg03959625 chr15:84868606 LOC388152 0.43 5.94 0.31 6.98e-9 Schizophrenia; LIHC trans rs60843830 1.000 rs62114548 chr2:274672 C/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.68 9.69 0.46 8.94e-20 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs7953508 0.711 rs10492321 chr12:93980088 T/A cg18151635 chr12:93972918 NA -0.44 -6.7 -0.34 8.6e-11 Pubertal anthropometrics; LIHC cis rs11683229 0.704 rs17850223 chr2:63283178 C/G cg17519650 chr2:63277830 OTX1 -0.55 -6.25 -0.32 1.19e-9 Protein quantitative trait loci; LIHC cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg16405210 chr4:1374714 KIAA1530 -0.74 -11.62 -0.53 1.51e-26 Longevity; LIHC cis rs295140 0.585 rs4233996 chr2:201131228 A/T cg23649088 chr2:200775458 C2orf69 -0.44 -6.12 -0.31 2.63e-9 QT interval; LIHC cis rs9355610 0.609 rs9366076 chr6:167373708 C/T cg23791538 chr6:167370224 RNASET2 0.58 9.14 0.44 5.54e-18 Graves' disease; LIHC cis rs4843747 0.749 rs72818535 chr16:88074039 G/A cg00677901 chr16:88017247 BANP 0.57 8.38 0.41 1.41e-15 Menopause (age at onset); LIHC cis rs826838 0.967 rs1684415 chr12:39130099 T/C cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs6964587 0.626 rs2269810 chr7:91508837 T/C cg17063962 chr7:91808500 NA -0.61 -11.04 -0.51 1.99e-24 Breast cancer; LIHC cis rs34779708 0.966 rs17500582 chr10:35498788 T/A cg03585969 chr10:35415529 CREM 0.85 12.81 0.57 6.11e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1801251 0.752 rs2592126 chr2:233751377 A/G cg25237894 chr2:233734115 C2orf82 -0.57 -10.97 -0.51 3.36e-24 Coronary artery disease; LIHC cis rs7412746 0.658 rs4537557 chr1:150734436 A/G cg17724175 chr1:150552817 MCL1 0.48 9.3 0.45 1.65e-18 Melanoma; LIHC cis rs7100689 0.784 rs7089058 chr10:82071263 T/C cg00277334 chr10:82204260 NA -0.55 -6.91 -0.35 2.43e-11 Post bronchodilator FEV1; LIHC cis rs2180341 0.781 rs7760652 chr6:127572096 A/G cg24812749 chr6:127587940 RNF146 0.66 9.63 0.46 1.37e-19 Breast cancer; LIHC cis rs1577917 0.740 rs2758845 chr6:86334848 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.24 -0.32 1.27e-9 Response to antipsychotic treatment; LIHC cis rs9628987 0.500 rs1443929 chr1:8457623 A/C cg20416874 chr1:8611966 RERE -0.5 -5.95 -0.31 6.78e-9 Breast cancer; LIHC cis rs9814567 0.928 rs6768323 chr3:134268737 A/C cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6951245 0.554 rs78999139 chr7:1138525 G/A cg22907277 chr7:1156413 C7orf50 0.86 8.15 0.4 6.97e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6964587 0.967 rs6465353 chr7:91779971 G/T cg17063962 chr7:91808500 NA -1.05 -22.37 -0.77 6.41e-69 Breast cancer; LIHC cis rs10911251 0.546 rs944971 chr1:183112505 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 3.82e-23 Colorectal cancer; LIHC cis rs6708331 0.517 rs11890741 chr2:70360506 T/C cg01613454 chr2:70366299 NA 0.38 6.11 0.31 2.75e-9 Obesity-related traits; LIHC cis rs8060686 0.545 rs55897859 chr16:68286748 G/C cg09835421 chr16:68378352 PRMT7 -0.57 -6.58 -0.34 1.81e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs600806 0.815 rs4970758 chr1:109979617 A/G cg16275483 chr1:110013120 SYPL2 -0.47 -5.82 -0.3 1.32e-8 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.941 rs1434079 chr2:26284670 C/G cg26119090 chr2:26468346 HADHA;HADHB -0.73 -8.95 -0.44 2.26e-17 Gut microbiome composition (summer); LIHC trans rs9926296 0.581 rs6500457 chr16:89898764 C/G cg13698153 chr12:118541722 VSIG10 -0.61 -6.55 -0.33 2.12e-10 Vitiligo; LIHC cis rs28489187 0.706 rs2300634 chr1:85791257 T/C cg16011679 chr1:85725395 C1orf52 0.48 6.15 0.32 2.13e-9 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs7659604 0.643 rs6839054 chr4:122663628 C/T cg19748678 chr4:122722346 EXOSC9 0.45 6.87 0.35 3.09e-11 Type 2 diabetes; LIHC cis rs11098499 0.909 rs28668716 chr4:120309875 T/C cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs780094 0.564 rs4665978 chr2:27648726 T/C cg22903471 chr2:27725779 GCKR -0.43 -7.19 -0.36 4.24e-12 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg21782813 chr7:2030301 MAD1L1 0.55 9.74 0.47 5.82e-20 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10352719 chr14:24769404 DHRS1;C14orf21 0.52 7.48 0.37 6.23e-13 Pancreatic cancer; LIHC cis rs6502050 0.835 rs9900072 chr17:80114360 C/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs6066825 0.644 rs761272 chr20:47315581 A/G cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.51e-12 Colorectal cancer; LIHC cis rs6977660 0.714 rs12672257 chr7:19813466 C/T cg07541023 chr7:19748670 TWISTNB 0.4 5.88 0.3 9.79e-9 Thyroid stimulating hormone; LIHC cis rs6952808 0.501 rs3778999 chr7:2180885 G/A cg02951883 chr7:2050386 MAD1L1 -0.62 -9.88 -0.47 2.06e-20 Bipolar disorder and schizophrenia; LIHC cis rs6964587 0.740 rs2020360 chr7:91439506 G/C cg17063962 chr7:91808500 NA 0.96 17.25 0.68 2.04e-48 Breast cancer; LIHC cis rs9790314 0.582 rs11708813 chr3:160589852 G/A cg03342759 chr3:160939853 NMD3 0.48 5.82 0.3 1.37e-8 Morning vs. evening chronotype; LIHC cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg20818283 chr2:191399100 TMEM194B -0.45 -6.06 -0.31 3.62e-9 Pulse pressure; LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.61 8.62 0.42 2.52e-16 Lymphocyte counts; LIHC cis rs3806843 0.933 rs2337987 chr5:140188383 T/G cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2404602 0.709 rs11072597 chr15:76763514 C/A cg03037974 chr15:76606532 NA -0.63 -10.88 -0.51 7.1e-24 Blood metabolite levels; LIHC cis rs3820068 0.581 rs72645895 chr1:15931709 G/A cg17385448 chr1:15911702 AGMAT 0.34 5.85 0.3 1.16e-8 Systolic blood pressure; LIHC cis rs7095944 0.614 rs1055256 chr10:126446592 A/G cg20435097 chr10:126320824 FAM53B 0.38 6.35 0.32 6.88e-10 Asthma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06617136 chr1:145470297 ANKRD34A;POLR3GL 0.44 7.23 0.36 3.25e-12 Cognitive function; LIHC cis rs10876993 0.928 rs1628552 chr12:58082142 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.04 -0.31 4.03e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs4423214 0.959 rs11233747 chr11:71171642 G/A cg05163923 chr11:71159392 DHCR7 0.89 13.62 0.59 4.7e-34 Vitamin D levels; LIHC cis rs7131987 0.868 rs10771508 chr12:29414211 G/A cg14222432 chr12:29376421 FAR2 0.36 7.05 0.36 9.82e-12 QT interval; LIHC cis rs11676348 0.935 rs2230054 chr2:219000310 C/T cg00012203 chr2:219082015 ARPC2 -0.53 -7.34 -0.37 1.57e-12 Ulcerative colitis; LIHC cis rs7095944 0.585 rs7080838 chr10:126419841 A/G cg08799069 chr10:126477246 METTL10 0.36 6.33 0.32 7.48e-10 Asthma; LIHC cis rs2455799 0.613 rs11712323 chr3:15891360 T/C cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.96e-13 Mean platelet volume; LIHC cis rs7617773 0.780 rs6793239 chr3:48351618 G/T cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs6762 0.748 rs7928935 chr11:839127 G/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.78 -9.49 -0.46 4.23e-19 Mean platelet volume; LIHC cis rs738322 1.000 rs738322 chr22:38569006 A/G cg25457927 chr22:38595422 NA -0.26 -6.37 -0.33 6.13e-10 Cutaneous nevi; LIHC cis rs1577917 1.000 rs2816815 chr6:86691656 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.78 -0.39 8.77e-14 Response to antipsychotic treatment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01704976 chr3:52273381 TWF2 0.45 6.16 0.32 2.07e-9 Lung function (FEV1/FVC); LIHC cis rs35306767 0.714 rs28512382 chr10:1092195 G/C cg26597838 chr10:835615 NA 0.76 7.39 0.37 1.15e-12 Eosinophil percentage of granulocytes; LIHC cis rs1005277 0.502 rs2800484 chr10:38542415 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.08 -0.44 8.66e-18 Extrinsic epigenetic age acceleration; LIHC cis rs2777491 1.000 rs11631770 chr15:41737059 T/C cg18705301 chr15:41695430 NDUFAF1 -0.59 -9.07 -0.44 9.75e-18 Ulcerative colitis; LIHC trans rs983392 0.679 rs764859 chr11:59978255 C/G cg17275991 chr19:58003312 ZNF419 0.44 6.35 0.32 6.84e-10 Alzheimer's disease (late onset); LIHC cis rs5753618 0.509 rs2079431 chr22:31564334 C/T cg07713946 chr22:31675144 LIMK2 -0.42 -7.43 -0.37 8.64e-13 Colorectal cancer; LIHC cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.36 0.45 1.11e-18 Bipolar disorder; LIHC cis rs797680 0.856 rs627779 chr1:93684089 T/C cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.88 0.3 1e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs4319547 0.620 rs12372756 chr12:122815130 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.36 -0.37 1.4e-12 Body mass index; LIHC cis rs151997 0.777 rs6870880 chr5:50256207 G/A cg06027927 chr5:50259733 NA 0.6 8.31 0.41 2.35e-15 Callous-unemotional behaviour; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg05679093 chr2:86426460 MRPL35 -0.42 -6.72 -0.34 7.62e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs1728785 0.901 rs1170437 chr16:68607943 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.37 0.33 6.01e-10 Ulcerative colitis; LIHC cis rs9902453 0.933 rs9908901 chr17:28469713 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.13 0.44 6.08e-18 Coffee consumption (cups per day); LIHC cis rs35306767 0.807 rs61831436 chr10:837882 G/A cg09361094 chr10:834503 NA -0.53 -5.78 -0.3 1.72e-8 Eosinophil percentage of granulocytes; LIHC trans rs1005277 0.579 rs1740747 chr10:38520465 G/A cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs2637030 0.559 rs2637024 chr5:52993453 A/G cg06476337 chr5:52856530 NDUFS4 0.42 6.75 0.34 6.4e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs10056811 0.538 rs3923323 chr5:74372141 C/T cg19683494 chr5:74908142 NA -0.71 -8.15 -0.4 6.98e-15 Coronary artery disease; LIHC cis rs34779708 0.750 rs35032841 chr10:35312687 G/A cg03585969 chr10:35415529 CREM 0.77 11.55 0.53 2.86e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg04317338 chr11:64019027 PLCB3 0.87 10.8 0.5 1.32e-23 Mean platelet volume; LIHC cis rs2242116 0.900 rs4683300 chr3:46934292 C/A cg23352942 chr3:46931381 PTH1R -0.33 -8.84 -0.43 4.97e-17 Birth weight; LIHC trans rs1814175 0.817 rs1794162 chr11:49899506 A/C cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs769267 0.965 rs8103496 chr19:19386015 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 11.66 0.53 1.15e-26 Alzheimer's disease; LIHC cis rs2836950 0.520 rs8133927 chr21:40689961 G/T cg06238570 chr21:40685208 BRWD1 -0.45 -7.42 -0.37 9.54e-13 Menarche (age at onset); LIHC cis rs1707322 0.691 rs12031182 chr1:46220999 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg12516959 chr21:47718080 NA -0.36 -5.96 -0.31 6.14e-9 Testicular germ cell tumor; LIHC cis rs17401966 1.000 rs4846210 chr1:10322153 A/G cg19773385 chr1:10388646 KIF1B -0.49 -8.32 -0.41 2.1e-15 Hepatocellular carcinoma; LIHC cis rs763121 1.000 rs1946990 chr22:38912771 C/T cg06022373 chr22:39101656 GTPBP1 -0.61 -11.51 -0.53 3.91e-26 Menopause (age at onset); LIHC cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.09 0.4 1.02e-14 Platelet count; LIHC cis rs4268898 0.662 rs55661701 chr2:24400769 A/C cg06627628 chr2:24431161 ITSN2 -0.69 -8.98 -0.44 1.9e-17 Asthma; LIHC cis rs9309473 0.687 rs12465867 chr2:73612102 C/T cg20560298 chr2:73613845 ALMS1 -0.48 -7.67 -0.38 1.85e-13 Metabolite levels; LIHC cis rs7587476 0.954 rs3768708 chr2:215645046 C/T cg04530015 chr2:215796436 ABCA12 0.4 6.49 0.33 3e-10 Neuroblastoma; LIHC cis rs3204270 0.714 rs7503307 chr17:79674929 C/G cg18367735 chr17:79674897 NA 0.73 8.54 0.42 4.6e-16 Dental caries; LIHC trans rs11098499 1.000 rs7659194 chr4:120207147 T/G cg25214090 chr10:38739885 LOC399744 0.5 7.72 0.39 1.25e-13 Corneal astigmatism; LIHC cis rs523522 0.962 rs11065154 chr12:120971417 T/C cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC trans rs3780486 0.846 rs3824458 chr9:33144809 C/T cg04842962 chr6:43655489 MRPS18A 1.06 24.64 0.8 8.62e-78 IgG glycosylation; LIHC cis rs10876993 0.928 rs1689587 chr12:58075398 A/G cg15848620 chr12:58087721 OS9 -0.59 -8.1 -0.4 9.68e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs600806 0.888 rs6695482 chr1:109870859 C/G cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.92 -0.3 7.78e-9 Intelligence (multi-trait analysis); LIHC cis rs2073499 1.000 rs79499880 chr3:50259551 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.63 6.36 0.32 6.65e-10 Schizophrenia; LIHC cis rs2708977 0.692 rs17685766 chr2:97319534 G/C cg01950434 chr2:97203154 ARID5A 0.5 7.13 0.36 5.93e-12 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.84 0.54 2.44e-27 Prudent dietary pattern; LIHC cis rs56104184 0.723 rs73063522 chr19:49408358 C/G cg21252483 chr19:49399788 TULP2 -1.0 -11.73 -0.54 6.22e-27 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs3806843 0.619 rs2569160 chr5:140028774 T/C cg16577123 chr5:140027231 NDUFA2;IK -0.41 -5.83 -0.3 1.29e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs208520 0.690 rs10455594 chr6:66737894 C/G cg07460842 chr6:66804631 NA 0.78 9.07 0.44 9.76e-18 Exhaled nitric oxide output; LIHC cis rs3093024 0.595 rs4412174 chr6:167476066 A/G cg07741184 chr6:167504864 NA 0.35 8.08 0.4 1.15e-14 Rheumatoid arthritis; LIHC cis rs7552404 0.883 rs7513363 chr1:76143443 A/G cg10523679 chr1:76189770 ACADM 0.67 10.03 0.48 6.56e-21 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10847980 1.000 rs10847980 chr12:123387922 G/T cg25930673 chr12:123319894 HIP1R -0.67 -7.55 -0.38 4.08e-13 Adiponectin levels; LIHC cis rs2370759 1.000 rs76467481 chr10:32610740 T/G cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs11955398 0.625 rs10805370 chr5:59984244 A/T cg02684056 chr5:59996105 DEPDC1B 0.44 6.25 0.32 1.23e-9 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.967 rs1906450 chr17:28515744 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.56 8.72 0.43 1.21e-16 Coffee consumption (cups per day); LIHC cis rs801193 1.000 rs2707845 chr7:66198798 C/T cg00343986 chr7:65444356 GUSB 0.41 6.1 0.31 2.86e-9 Aortic root size; LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg00106254 chr7:1943704 MAD1L1 -0.42 -6.82 -0.35 4.05e-11 Bipolar disorder and schizophrenia; LIHC cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg17747265 chr1:1875780 NA 0.51 8.8 0.43 7.09e-17 Body mass index; LIHC cis rs11098499 0.818 rs7688802 chr4:120451668 G/A cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs34375054 0.525 rs7133614 chr12:125605957 C/T cg25124228 chr12:125621409 AACS -0.5 -9.49 -0.46 4.06e-19 Post bronchodilator FEV1/FVC ratio; LIHC cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg19318889 chr4:1322082 MAEA 0.47 7.48 0.38 6.2800000000000005e-13 Longevity; LIHC cis rs611744 0.967 rs569701 chr8:109239207 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs4650994 0.571 rs6425486 chr1:178528822 G/A cg05350800 chr1:178550844 NA -0.34 -7.38 -0.37 1.19e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7131987 0.650 rs11050188 chr12:29473108 A/C cg16970926 chr12:29381810 FAR2 0.28 5.89 0.3 9.1e-9 QT interval; LIHC cis rs12701220 0.522 rs868833 chr7:1054973 C/G cg04025307 chr7:1156635 C7orf50 0.47 6.71 0.34 8.08e-11 Bronchopulmonary dysplasia; LIHC trans rs3942852 0.774 rs1039481 chr11:48182237 G/A cg15704280 chr7:45808275 SEPT13 -0.59 -8.01 -0.4 1.77e-14 Acute lymphoblastic leukemia (childhood); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01056155 chr5:72794294 BTF3 -0.48 -6.2 -0.32 1.67e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.08 0.44 9.16e-18 Platelet count; LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg06873352 chr17:61820015 STRADA 0.73 12.64 0.56 2.61e-30 Prudent dietary pattern; LIHC cis rs4478037 0.749 rs9311003 chr3:33131070 A/G cg27203090 chr3:33138513 GLB1;TMPPE 0.53 6.96 0.35 1.8e-11 Major depressive disorder; LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg14671364 chr1:107599128 PRMT6 -0.53 -7.69 -0.38 1.56e-13 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs9951602 0.512 rs77157626 chr18:76644771 C/T cg02800362 chr5:177631904 HNRNPAB 0.65 10.34 0.49 5.33e-22 Obesity-related traits; LIHC cis rs3784262 1.000 rs4646640 chr15:58247563 C/G cg12031962 chr15:58353849 ALDH1A2 0.31 6.21 0.32 1.58e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01073178 chr12:117537710 TESC 0.6 8.11 0.4 9.33e-15 Lung function (FEV1/FVC); LIHC cis rs2228479 0.850 rs62052714 chr16:89857180 T/C cg19635926 chr16:89946313 TCF25 0.54 6.77 0.34 5.65e-11 Skin colour saturation; LIHC trans rs66573146 0.572 rs73199995 chr4:6955801 G/C cg07817883 chr1:32538562 TMEM39B 1.02 9.01 0.44 1.54e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs2710642 0.566 rs2710651 chr2:63166379 G/A cg17519650 chr2:63277830 OTX1 0.58 9.65 0.46 1.23e-19 LDL cholesterol levels;LDL cholesterol; LIHC cis rs60871478 0.898 rs4725241 chr7:796883 C/T cg04727924 chr7:799746 HEATR2 -0.57 -8.36 -0.41 1.64e-15 Cerebrospinal P-tau181p levels; LIHC cis rs933688 0.938 rs1477348 chr5:90707823 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.7 0.73 2.92e-58 Smoking behavior; LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.24 -0.32 1.29e-9 Total body bone mineral density; LIHC cis rs9381040 0.655 rs2268190 chr6:41030226 C/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.44 -0.33 4.05e-10 Alzheimer's disease (late onset); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg07227769 chr11:67479369 NA 0.33 6.05 0.31 3.83e-9 Bilirubin levels; LIHC cis rs9810089 0.708 rs711977 chr3:136227387 G/A cg21827317 chr3:136751795 NA 0.45 6.03 0.31 4.15e-9 Gestational age at birth (child effect); LIHC cis rs4689642 0.709 rs13115404 chr4:7226101 T/G cg21353189 chr4:7228343 SORCS2 0.37 6.24 0.32 1.29e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -11.04 -0.51 2e-24 Platelet count; LIHC cis rs826838 1.000 rs10875991 chr12:39108886 G/C cg13010199 chr12:38710504 ALG10B 0.53 6.48 0.33 3.19e-10 Heart rate; LIHC cis rs7116495 0.609 rs674319 chr11:71775391 T/C cg26138937 chr11:71823887 C11orf51 -1.32 -10.43 -0.49 2.71e-22 Severe influenza A (H1N1) infection; LIHC cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg16970926 chr12:29381810 FAR2 0.34 7.4 0.37 1.05e-12 QT interval; LIHC cis rs79149102 0.579 rs3816261 chr15:75336173 T/A cg15902774 chr15:75289873 SCAMP5 0.46 6.48 0.33 3.19e-10 Lung cancer; LIHC cis rs1568889 1.000 rs35343234 chr11:28034379 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.83 0.35 3.84e-11 Bipolar disorder; LIHC cis rs7552404 0.655 rs1146646 chr1:76265500 G/A cg10523679 chr1:76189770 ACADM 0.6 8.02 0.4 1.72e-14 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4319547 0.741 rs4758644 chr12:122943915 A/C cg23029597 chr12:123009494 RSRC2 -0.48 -6.89 -0.35 2.62e-11 Body mass index; LIHC cis rs921968 0.643 rs559722 chr2:219398159 A/G cg18887096 chr2:219472410 PLCD4 0.36 6.44 0.33 4.12e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg10944116 chr2:242448158 STK25 -0.44 -6.32 -0.32 8.19e-10 Immature fraction of reticulocytes; LIHC cis rs6089584 0.821 rs2273990 chr20:60579149 G/T cg13770153 chr20:60521292 NA -0.33 -6.4 -0.33 5.2400000000000005e-10 Body mass index; LIHC cis rs644799 0.965 rs565771 chr11:95644179 T/A cg25478527 chr11:95522999 CEP57;FAM76B 0.44 6.08 0.31 3.25e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05756109 chr10:103347662 POLL;RP11-529I10.4 0.44 6.24 0.32 1.32e-9 Lung function (FEV1/FVC); LIHC cis rs8114671 0.562 rs6088640 chr20:33472509 C/T cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.02e-19 Height; LIHC cis rs6499255 1.000 rs55992518 chr16:69821407 C/T cg15192750 chr16:69999425 NA 0.44 6.46 0.33 3.64e-10 IgE levels; LIHC cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg18252515 chr7:66147081 NA 1.27 16.7 0.67 3.42e-46 Diabetic kidney disease; LIHC cis rs1538970 0.781 rs34768551 chr1:46020408 G/A cg06784218 chr1:46089804 CCDC17 0.37 5.96 0.31 6.37e-9 Platelet count; LIHC cis rs7208859 0.623 rs28433704 chr17:29084285 G/C cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6489882 0.836 rs6489878 chr12:113368125 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg10295955 chr4:187884368 NA -0.95 -21.01 -0.75 1.61e-63 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs4665809 1.000 rs6546768 chr2:26328800 A/G cg27170947 chr2:26402098 FAM59B -0.65 -8.22 -0.41 4.22e-15 Gut microbiome composition (summer); LIHC cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg21724239 chr8:58056113 NA 0.47 6.24 0.32 1.32e-9 Developmental language disorder (linguistic errors); LIHC cis rs16922576 0.623 rs2093446 chr9:5230371 G/C cg02405213 chr9:5042618 JAK2 -0.61 -8.95 -0.44 2.35e-17 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2933343 0.649 rs789216 chr3:128594503 A/C cg25356066 chr3:128598488 ACAD9 0.56 7.74 0.39 1.12e-13 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09704741 chr12:95867762 METAP2 -0.45 -6.28 -0.32 1e-9 Pancreatic cancer; LIHC cis rs17102884 0.506 rs4899541 chr14:75403437 T/G cg11812906 chr14:75593930 NEK9 -0.47 -7.93 -0.39 3.08e-14 Neuroticism; LIHC cis rs796364 0.906 rs281766 chr2:200820505 T/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.7 8.3 0.41 2.48e-15 Schizophrenia; LIHC cis rs11785693 0.862 rs11780705 chr8:4988221 G/A cg26367366 chr8:4980734 NA 0.6 6.46 0.33 3.53e-10 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs1707322 0.964 rs785483 chr1:46559171 T/C cg06784218 chr1:46089804 CCDC17 -0.37 -6.74 -0.34 6.8e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1005277 0.522 rs9418276 chr10:37940116 G/T cg23533926 chr12:111358616 MYL2 -0.33 -6.51 -0.33 2.71e-10 Extrinsic epigenetic age acceleration; LIHC trans rs7618501 1.000 rs4855862 chr3:49748833 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06966887 chr5:443603 EXOC3;C5orf55 0.42 6.7 0.34 8.4e-11 Cognitive function; LIHC cis rs7923452 0.938 rs34930615 chr10:30761051 G/A cg25182066 chr10:30743637 MAP3K8 0.68 9.68 0.46 9.69e-20 Itch intensity from mosquito bite; LIHC cis rs2282802 0.685 rs2337082 chr5:139649201 G/A cg26211634 chr5:139558579 C5orf32 0.39 5.98 0.31 5.58e-9 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.963 rs10789484 chr1:46406978 G/C cg03146154 chr1:46216737 IPP 0.48 7.89 0.39 4.16e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4144743 0.759 rs34251886 chr17:45320299 G/T cg18085866 chr17:45331354 ITGB3 -0.61 -7.16 -0.36 4.95e-12 Body mass index; LIHC cis rs6964587 1.000 rs6953515 chr7:91658620 C/T cg17063962 chr7:91808500 NA 1.03 19.93 0.73 3.51e-59 Breast cancer; LIHC cis rs6582630 0.502 rs11614397 chr12:38328163 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.41e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs7793919 0.726 rs10232008 chr7:4783206 T/G cg09789173 chr7:4769017 FOXK1 0.71 10.38 0.49 3.94e-22 Mosquito bite size; LIHC cis rs797680 0.754 rs7535214 chr1:93832565 A/AT cg15093775 chr1:93646470 TMED5;CCDC18 0.57 8.42 0.41 1.03e-15 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs1664789 0.904 rs1694057 chr5:53277373 T/A ch.5.1024479R chr5:53302184 ARL15 0.54 8.47 0.42 7.37e-16 Waist circumference adjusted for body mass index; LIHC cis rs1215050 0.716 rs11940331 chr4:99054041 G/C cg05340658 chr4:99064831 C4orf37 0.4 6.13 0.31 2.38e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs853679 0.824 rs34712084 chr6:28043828 A/G cg16479474 chr6:28041457 NA 0.5 5.88 0.3 9.81e-9 Depression; LIHC cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Electroencephalogram traits; LIHC cis rs4819052 0.851 rs8131143 chr21:46671646 C/G cg11663144 chr21:46675770 NA 0.32 6.0 0.31 5.04e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg14709524 chr16:89940631 TCF25 0.59 7.57 0.38 3.43e-13 Skin colour saturation; LIHC cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg05368731 chr17:41323189 NBR1 0.72 12.43 0.56 1.65e-29 Menopause (age at onset); LIHC cis rs17001868 0.568 rs10854729 chr22:40750612 T/C cg07138101 chr22:40742427 ADSL 0.53 6.45 0.33 3.9e-10 Mammographic density (dense area); LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.78 -0.34 5.15e-11 Lymphocyte counts; LIHC cis rs7772486 0.790 rs7753833 chr6:146161432 C/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.82e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs860295 1.000 rs822527 chr1:155738053 A/G cg02153340 chr1:155202674 NA 0.32 5.85 0.3 1.15e-8 Body mass index; LIHC cis rs7633770 0.735 rs11719679 chr3:46687684 A/G cg11219411 chr3:46661640 NA -0.42 -7.26 -0.37 2.59e-12 Coronary artery disease; LIHC cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg00149659 chr3:10157352 C3orf10 0.67 6.81 0.35 4.45e-11 Alzheimer's disease; LIHC cis rs11673344 0.734 rs1667343 chr19:37469098 G/A cg27390819 chr19:37464633 NA -0.5 -6.1 -0.31 2.94e-9 Obesity-related traits; LIHC cis rs910316 1.000 rs175512 chr14:75523382 T/C cg11812906 chr14:75593930 NEK9 -0.76 -14.89 -0.63 5.38e-39 Height; LIHC cis rs17384381 0.953 rs12138621 chr1:85783970 T/C cg16011679 chr1:85725395 C1orf52 0.85 9.11 0.44 7.33e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg17158414 chr2:27665306 KRTCAP3 -0.44 -5.98 -0.31 5.57e-9 Total body bone mineral density; LIHC cis rs35110281 0.720 rs162376 chr21:44926759 G/T cg21573476 chr21:45109991 RRP1B 0.61 11.3 0.52 2.24e-25 Mean corpuscular volume; LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg00809820 chr17:80708513 TBCD;FN3K 0.39 7.04 0.36 1.09e-11 Glycated hemoglobin levels; LIHC cis rs796364 1.000 rs769949 chr2:200729558 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.09 0.44 8.32e-18 Schizophrenia; LIHC cis rs7044106 0.762 rs966397 chr9:123453312 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.9 0.51 6.28e-24 Hip circumference adjusted for BMI; LIHC cis rs7847628 0.587 rs10760117 chr9:123586737 T/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.75 12.85 0.57 4.15e-31 Birth weight; LIHC trans rs7246657 0.882 rs28623164 chr19:37913453 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg18654377 chr3:49208889 KLHDC8B -0.5 -6.02 -0.31 4.45e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06506598 chr5:79783889 FAM151B 0.43 6.33 0.32 7.55e-10 Lung function (FEV1/FVC); LIHC cis rs796364 0.806 rs203769 chr2:200900866 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.83 -0.43 5.53e-17 Schizophrenia; LIHC cis rs7208859 0.673 rs9899525 chr17:29120296 T/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg18252515 chr7:66147081 NA 1.24 16.17 0.66 4.22e-44 Diabetic kidney disease; LIHC cis rs12048904 0.595 rs10493937 chr1:101342650 A/T cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.52 -7.71 -0.38 1.37e-13 Multiple sclerosis; LIHC cis rs7619427 1.000 rs7619427 chr3:44077041 G/A cg24966902 chr3:44043705 NA 0.5 7.05 0.36 9.76e-12 Schizophrenia; LIHC trans rs1814175 0.817 rs10839465 chr11:49981554 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs7959452 0.535 rs7308481 chr12:69659299 A/G cg14784868 chr12:69753453 YEATS4 0.88 16.68 0.67 4.15e-46 Blood protein levels; LIHC cis rs548181 1.000 rs548181 chr11:125461709 A/G cg03464685 chr11:125439445 EI24 1.08 11.24 0.52 3.76e-25 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8062405 0.929 rs11150609 chr16:28870596 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.74 -0.34 6.72e-11 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07479988 chr2:39103277 MORN2;DHX57 0.46 6.6 0.34 1.55e-10 Lung function (FEV1/FVC); LIHC cis rs7520050 0.966 rs11211241 chr1:46452683 T/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 6.03 0.31 4.24e-9 Red blood cell count;Reticulocyte count; LIHC cis rs477692 0.935 rs554458 chr10:131427372 A/G cg19680672 chr10:131412579 MGMT -0.43 -6.8 -0.34 4.8e-11 Response to temozolomide; LIHC cis rs7246865 0.859 rs1379281 chr19:17189786 A/G cg16202187 chr19:17186497 HAUS8;MYO9B -0.37 -5.71 -0.3 2.42e-8 Reticulocyte fraction of red cells; LIHC cis rs4555082 0.874 rs28785556 chr14:105745388 A/T cg13114125 chr14:105738426 BRF1 -0.79 -9.95 -0.47 1.14e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs10744422 0.858 rs7980541 chr12:123379477 C/T cg18912006 chr12:123335444 HIP1R -0.6 -7.26 -0.37 2.56e-12 Schizophrenia; LIHC cis rs1348850 0.914 rs7591807 chr2:178252986 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 13.97 0.6 2.02e-35 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7584330 0.554 rs6760890 chr2:238400645 G/A cg08992911 chr2:238395768 MLPH 0.63 6.48 0.33 3.29e-10 Prostate cancer; LIHC cis rs7762018 0.607 rs77004024 chr6:170063437 G/A cg19338460 chr6:170058176 WDR27 -0.89 -9.53 -0.46 3.06e-19 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs597539 0.652 rs513359 chr11:68669496 A/T cg04772025 chr11:68637568 NA -0.45 -5.93 -0.31 7.27e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs60871478 0.947 rs62432862 chr7:807719 G/C cg05535760 chr7:792225 HEATR2 0.8 11.14 0.52 8.76e-25 Cerebrospinal P-tau181p levels; LIHC cis rs2463822 0.920 rs7924998 chr11:62073980 C/G cg06239285 chr11:62104954 ASRGL1 -1.0 -6.98 -0.35 1.58e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs8180040 0.676 rs7636252 chr3:47013542 T/G cg16586182 chr3:47516702 SCAP -0.46 -8.35 -0.41 1.73e-15 Colorectal cancer; LIHC cis rs10916814 0.610 rs1890004 chr1:20899066 T/C cg24502330 chr1:20914028 CDA -0.3 -6.7 -0.34 8.63e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9646954 0.542 rs3828193 chr2:101031561 A/C cg14675211 chr2:100938903 LONRF2 -0.49 -7.57 -0.38 3.6e-13 Intelligence (multi-trait analysis); LIHC trans rs2270927 0.510 rs6876070 chr5:75579237 T/A cg13563193 chr19:33072644 PDCD5 0.99 9.35 0.45 1.2e-18 Mean corpuscular volume; LIHC cis rs6429082 0.811 rs291348 chr1:235667690 A/G cg26050004 chr1:235667680 B3GALNT2 0.82 14.91 0.63 4.55e-39 Adiposity; LIHC trans rs6489882 0.671 rs4767026 chr12:113359132 A/G cg10175203 chr3:128143634 NA 0.39 6.4 0.33 5.08e-10 Chronic lymphocytic leukemia; LIHC cis rs5769765 0.779 rs12170530 chr22:50318422 T/G cg02269571 chr22:50332266 NA -0.66 -9.07 -0.44 9.22e-18 Schizophrenia; LIHC cis rs11098499 0.863 rs6835635 chr4:120458867 A/G cg09307838 chr4:120376055 NA 0.74 11.26 0.52 3.25e-25 Corneal astigmatism; LIHC trans rs9914544 0.545 rs9898426 chr17:18794071 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.47 -0.33 3.37e-10 Educational attainment (years of education); LIHC cis rs7246657 0.943 rs10405064 chr19:37861861 C/T cg23950597 chr19:37808831 NA -0.49 -6.41 -0.33 4.73e-10 Coronary artery calcification; LIHC cis rs4474465 0.688 rs4945302 chr11:78283454 T/C cg02023728 chr11:77925099 USP35 -0.34 -5.99 -0.31 5.41e-9 Alzheimer's disease (survival time); LIHC cis rs780096 0.527 rs12471703 chr2:27738854 C/T cg27432699 chr2:27873401 GPN1 -0.6 -8.66 -0.42 1.88e-16 Total body bone mineral density; LIHC cis rs732505 0.850 rs10412919 chr19:5586749 T/C cg26242866 chr19:5711310 LONP1 0.89 6.52 0.33 2.59e-10 vWF and FVIII levels; LIHC cis rs1198430 0.683 rs1198433 chr1:23756695 A/G cg19827787 chr1:23763612 ASAP3 0.29 6.15 0.32 2.13e-9 Total cholesterol levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07775675 chr17:74379922 SPHK1 0.46 6.86 0.35 3.17e-11 Pancreatic cancer; LIHC cis rs2834215 0.718 rs8128364 chr21:34867525 C/A cg14850771 chr21:34775459 IFNGR2 0.42 6.07 0.31 3.39e-9 Crohn's disease; LIHC trans rs10506458 0.915 rs2013042 chr12:63394211 A/G cg22491629 chr6:157744540 C6orf35 -0.59 -10.78 -0.5 1.64e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg18305652 chr10:134549665 INPP5A 0.51 7.96 0.4 2.6e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9733 0.503 rs7556451 chr1:150913142 A/G cg17724175 chr1:150552817 MCL1 0.38 7.59 0.38 3.03e-13 Tonsillectomy; LIHC cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg12463550 chr7:65579703 CRCP 0.62 7.25 0.36 2.88e-12 Diabetic kidney disease; LIHC cis rs10751667 0.643 rs7942693 chr11:957832 G/A cg06064525 chr11:970664 AP2A2 -0.56 -15.03 -0.63 1.52e-39 Alzheimer's disease (late onset); LIHC cis rs546131 0.890 rs485845 chr11:34830389 G/T cg06937548 chr11:34938143 PDHX;APIP -0.58 -7.69 -0.38 1.61e-13 Lung disease severity in cystic fibrosis; LIHC cis rs78545713 0.649 rs11754368 chr6:26221173 G/A cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs17685 0.753 rs6464999 chr7:75787315 T/C cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2439831 0.867 rs2920781 chr15:43924682 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.28 0.45 2.02e-18 Lung cancer in ever smokers; LIHC cis rs1707322 1.000 rs7538978 chr1:46505054 C/T cg03146154 chr1:46216737 IPP -0.45 -7.38 -0.37 1.18e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg25072359 chr17:41440525 NA 0.38 6.12 0.31 2.63e-9 Menopause (age at onset); LIHC cis rs9393777 0.588 rs9467772 chr6:26496578 A/T cg12826209 chr6:26865740 GUSBL1 0.68 8.24 0.41 3.79e-15 Intelligence (multi-trait analysis); LIHC cis rs10876993 0.821 rs1629032 chr12:58038686 C/T cg15848620 chr12:58087721 OS9 -0.55 -7.52 -0.38 4.99e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs738322 1.000 rs133012 chr22:38570721 G/A cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs7100689 0.784 rs10736342 chr10:82130005 A/G cg00277334 chr10:82204260 NA -0.54 -6.68 -0.34 9.51e-11 Post bronchodilator FEV1; LIHC cis rs4755351 0.553 rs61887100 chr11:33170390 T/C cg05567920 chr11:33183001 CSTF3 0.42 6.21 0.32 1.56e-9 Lung cancer in ever smokers; LIHC cis rs9300255 0.602 rs6488864 chr12:123618362 G/C cg00376283 chr12:123451042 ABCB9 0.58 7.41 0.37 1e-12 Neutrophil percentage of white cells; LIHC trans rs1814175 0.645 rs28445479 chr11:50047999 A/G cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg10360323 chr17:41437877 NA 0.4 5.92 0.31 7.69e-9 Menopause (age at onset); LIHC trans rs2243480 1.000 rs6460260 chr7:65215455 T/C cg10756647 chr7:56101905 PSPH -1.11 -13.62 -0.59 4.91e-34 Diabetic kidney disease; LIHC cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg00684032 chr4:1343700 KIAA1530 0.53 7.73 0.39 1.24e-13 Obesity-related traits; LIHC cis rs875971 0.660 rs62465434 chr7:66005152 A/C cg00343986 chr7:65444356 GUSB 0.4 6.05 0.31 3.88e-9 Aortic root size; LIHC cis rs7100689 0.646 rs10749579 chr10:82140959 C/T cg00277334 chr10:82204260 NA -0.59 -7.71 -0.38 1.36e-13 Post bronchodilator FEV1; LIHC cis rs2842992 0.709 rs1853257 chr6:160212710 C/G cg11366901 chr6:160182831 ACAT2 0.93 15.46 0.64 3.05e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs13191362 1.000 rs13210412 chr6:163019478 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.61 5.77 0.3 1.77e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7107174 1.000 rs58235466 chr11:78030886 T/C cg02023728 chr11:77925099 USP35 0.46 9.03 0.44 1.25e-17 Testicular germ cell tumor; LIHC cis rs3820068 0.705 rs11587541 chr1:15899478 T/C cg17385448 chr1:15911702 AGMAT 0.42 6.97 0.35 1.65e-11 Systolic blood pressure; LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg03854865 chr6:26224070 HIST1H3E 0.63 7.23 0.36 3.28e-12 Gout;Renal underexcretion gout; LIHC cis rs1461503 0.932 rs10790544 chr11:122838330 T/C cg14473756 chr11:122847823 NA -0.37 -6.65 -0.34 1.18e-10 Menarche (age at onset); LIHC cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg04267008 chr7:1944627 MAD1L1 -0.7 -10.87 -0.51 7.47e-24 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs2204008 0.614 rs4578492 chr12:38036350 T/C cg26384229 chr12:38710491 ALG10B 0.85 10.57 0.5 9e-23 Bladder cancer; LIHC cis rs950776 0.714 rs17408276 chr15:78881618 T/C cg06917634 chr15:78832804 PSMA4 0.66 8.92 0.43 2.83e-17 Sudden cardiac arrest; LIHC trans rs1005277 0.579 rs1740747 chr10:38520465 G/A cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs7914558 1.000 rs12780843 chr10:104769335 G/C cg15744005 chr10:104629667 AS3MT -0.39 -8.75 -0.43 1e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9611565 0.559 rs132768 chr22:42013523 C/A cg06634786 chr22:41940651 POLR3H 0.71 7.38 0.37 1.23e-12 Vitiligo; LIHC cis rs72781680 0.752 rs72796114 chr2:23906133 C/G cg08917208 chr2:24149416 ATAD2B 0.98 8.06 0.4 1.29e-14 Lymphocyte counts; LIHC cis rs17401966 0.838 rs10492971 chr1:10342975 G/A cg19773385 chr1:10388646 KIF1B -0.4 -7.22 -0.36 3.44e-12 Hepatocellular carcinoma; LIHC cis rs11098499 0.863 rs6853998 chr4:120475860 C/A cg09307838 chr4:120376055 NA 0.75 11.33 0.52 1.79e-25 Corneal astigmatism; LIHC cis rs807669 0.835 rs698423 chr22:19197896 T/C cg02655711 chr22:19163373 SLC25A1 0.7 10.5 0.49 1.56e-22 Metabolite levels; LIHC cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg08888203 chr3:10149979 C3orf24 0.56 6.45 0.33 3.89e-10 Alzheimer's disease; LIHC cis rs17776563 0.887 rs8024132 chr15:89132681 G/T cg05013243 chr15:89149849 MIR1179 0.41 6.77 0.34 5.49e-11 Thyroid hormone levels; LIHC cis rs10751667 0.580 rs7395515 chr11:1005160 C/T cg06064525 chr11:970664 AP2A2 -0.44 -10.71 -0.5 2.94e-23 Alzheimer's disease (late onset); LIHC cis rs1707322 1.000 rs10890355 chr1:46317348 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07222421 chr1:155718648 MSTO2P 0.4 6.07 0.31 3.47e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3096299 0.591 rs748940 chr16:89440757 T/A cg08822215 chr16:89438651 ANKRD11 -0.48 -7.7 -0.38 1.48e-13 Multiple myeloma (IgH translocation); LIHC cis rs3743266 0.507 rs56261931 chr15:60731618 C/T cg22293140 chr15:60689852 ANXA2 -0.65 -6.48 -0.33 3.15e-10 Menarche (age at onset); LIHC cis rs4975616 0.869 rs31490 chr5:1344458 G/A cg07493874 chr5:1342172 CLPTM1L -0.66 -10.55 -0.5 1.04e-22 Lung cancer; LIHC trans rs1005277 0.579 rs2505197 chr10:38393310 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs738322 0.577 rs4820320 chr22:38572977 G/A cg25457927 chr22:38595422 NA -0.24 -5.71 -0.3 2.42e-8 Cutaneous nevi; LIHC cis rs12019136 1 rs12019136 chr19:5835677 G/A cg25387410 chr19:5844109 FUT3 -0.71 -8.47 -0.42 7.5e-16 Advanced age-related macular degeneration;IgG N-glycosylation phenotypes (multivariate analysis); LIHC cis rs2228479 0.717 rs11644967 chr16:89806614 T/A cg00800038 chr16:89945340 TCF25 -0.62 -9.37 -0.45 9.82e-19 Skin colour saturation; LIHC cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 8.97 0.44 1.99e-17 Menarche (age at onset); LIHC cis rs10911251 0.546 rs2274984 chr1:183107446 A/C ch.1.3577855R chr1:183094577 LAMC1 -0.59 -10.26 -0.49 1.05e-21 Colorectal cancer; LIHC cis rs3020736 0.500 rs6002623 chr22:42513761 G/A cg15557168 chr22:42548783 NA 0.43 6.78 0.34 5.3e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs9325144 0.555 rs28738714 chr12:38706912 G/A cg26384229 chr12:38710491 ALG10B -0.57 -7.86 -0.39 4.89e-14 Morning vs. evening chronotype; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18122802 chr7:66459960 SBDS 0.43 6.45 0.33 3.76e-10 Cognitive function; LIHC trans rs1814175 0.817 rs12287396 chr11:49819798 G/C cg03929089 chr4:120376271 NA -0.9 -18.64 -0.71 5.26e-54 Height; LIHC cis rs1577917 0.727 rs9444361 chr6:86400900 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.67 12.79 0.57 6.73e-31 Response to antipsychotic treatment; LIHC cis rs12744310 0.943 rs12751511 chr1:41776403 A/T cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9381040 0.610 rs9381028 chr6:41025081 C/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.77 -0.3 1.82e-8 Alzheimer's disease (late onset); LIHC cis rs801193 0.636 rs2659895 chr7:66196471 C/A cg18252515 chr7:66147081 NA -0.43 -6.3 -0.32 9.36e-10 Aortic root size; LIHC cis rs2354432 0.505 rs4424556 chr1:146863973 G/C cg25205988 chr1:146714368 CHD1L 0.84 9.45 0.45 5.66e-19 Mitochondrial DNA levels; LIHC cis rs9768139 0.935 rs7809076 chr7:158118438 C/T cg25566285 chr7:158114605 PTPRN2 -0.26 -7.64 -0.38 2.25e-13 Calcium levels; LIHC cis rs6933660 0.745 rs6912830 chr6:151743629 A/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.55 -8.48 -0.42 6.74e-16 Menarche (age at onset); LIHC cis rs4660306 1.000 rs882803 chr1:45976147 G/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.57 -7.08 -0.36 8.42e-12 Homocysteine levels; LIHC cis rs7781266 0.501 rs28551473 chr7:133631089 G/C cg03336402 chr7:133662267 EXOC4 0.47 5.84 0.3 1.22e-8 Educational attainment (college completion); LIHC cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg13047869 chr3:10149882 C3orf24 -0.56 -6.77 -0.34 5.51e-11 Alzheimer's disease; LIHC cis rs10276381 0.579 rs58696040 chr7:28148387 A/G cg23620719 chr7:28220237 JAZF1 0.63 6.92 0.35 2.3e-11 Crohn's disease; LIHC cis rs782590 0.902 rs3762513 chr2:55762957 C/T cg18811423 chr2:55921094 PNPT1 0.98 15.17 0.63 4.33e-40 Metabolic syndrome; LIHC cis rs7917772 0.582 rs4919661 chr10:104358403 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7777484 0.500 rs757787 chr7:2836355 G/A cg19717773 chr7:2847554 GNA12 -0.45 -8.85 -0.43 4.74e-17 Height; LIHC trans rs11689435 0.925 rs3732007 chr2:218343265 A/G cg13544946 chr9:35729779 TLN1 0.43 6.14 0.32 2.27e-9 Metabolite levels (MHPG); LIHC cis rs9611565 0.532 rs4401299 chr22:42156517 A/G cg03806693 chr22:41940476 POLR3H 0.78 8.68 0.42 1.67e-16 Vitiligo; LIHC cis rs244293 0.672 rs9901526 chr17:53012379 G/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.56 -0.38 3.79e-13 Menarche (age at onset); LIHC cis rs7845219 0.539 rs713113 chr8:95877787 C/T cg23172400 chr8:95962367 TP53INP1 0.33 7.05 0.36 1e-11 Type 2 diabetes; LIHC trans rs12752401 1.000 rs67551785 chr1:102978472 T/C cg24921808 chr19:740313 PALM 0.49 6.39 0.33 5.33e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs17685 0.671 rs60303271 chr7:75760008 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6691722 0.503 rs3765428 chr1:24706113 G/A cg18323236 chr1:24743029 NIPAL3 0.39 7.25 0.37 2.73e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs6754311 0.731 rs6719488 chr2:136575199 G/T cg15123519 chr2:136567270 LCT 0.45 9.45 0.45 5.65e-19 Mosquito bite size; LIHC cis rs17345786 0.906 rs12638137 chr3:101150964 C/T cg12386194 chr3:101231763 SENP7 0.58 7.46 0.37 7.07e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs9811920 0.609 rs793501 chr3:99591638 T/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs1957429 0.901 rs2884308 chr14:65350406 A/T cg23373153 chr14:65346875 NA -0.82 -11.46 -0.53 5.75e-26 Pediatric areal bone mineral density (radius); LIHC cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg20818283 chr2:191399100 TMEM194B 0.46 6.31 0.32 8.66e-10 Pulse pressure; LIHC cis rs10791097 0.694 rs2155750 chr11:130751261 A/C cg12179176 chr11:130786555 SNX19 0.8 12.79 0.57 7.08e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9560113 0.960 rs4773378 chr13:112174154 G/A cg14154082 chr13:112174009 NA 0.29 6.1 0.31 2.81e-9 Menarche (age at onset); LIHC trans rs1728785 0.818 rs1170430 chr16:68604954 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs7552404 1.000 rs7513559 chr1:76173744 A/G cg22875332 chr1:76189707 ACADM 0.47 6.74 0.34 6.6e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs61677309 1.000 rs58093803 chr11:118168156 T/C cg06090739 chr11:118230722 UBE4A 0.35 6.41 0.33 4.89e-10 Lung cancer in ever smokers; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20707008 chr6:160210612 MRPL18;TCP1 0.42 6.19 0.32 1.7e-9 Cognitive function; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.7 0.62 2.88e-38 Prudent dietary pattern; LIHC cis rs72653721 0.689 rs4711170 chr6:11070434 C/A cg13562911 chr6:11044106 ELOVL2 0.51 7.27 0.37 2.42e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs8108269 0.955 rs55872740 chr19:46160323 A/G cg13320842 chr19:46175254 GIPR 0.41 7.7 0.38 1.5e-13 Type 2 diabetes; LIHC cis rs2204008 0.715 rs3899385 chr12:38169880 C/G cg26384229 chr12:38710491 ALG10B 0.82 10.25 0.48 1.14e-21 Bladder cancer; LIHC cis rs3845702 0.668 rs3856415 chr2:180807367 G/A cg01881094 chr2:180872142 CWC22 -1.15 -9.94 -0.47 1.3e-20 Schizophrenia; LIHC cis rs6430585 0.583 rs12475516 chr2:136560761 C/G cg07169764 chr2:136633963 MCM6 1.12 17.17 0.68 4.25e-48 Corneal structure; LIHC cis rs870825 0.616 rs6552804 chr4:185637699 A/G cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg16497277 chr3:49208875 KLHDC8B -0.49 -6.09 -0.31 2.97e-9 Menarche (age at onset); LIHC cis rs921968 0.565 rs6436070 chr2:219597960 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs12478296 0.515 rs13412492 chr2:243000583 T/G cg01596870 chr19:55963115 NA -0.66 -9.72 -0.47 7.09e-20 Obesity-related traits; LIHC cis rs10242455 0.571 rs73713594 chr7:99326498 A/G cg18809830 chr7:99032528 PTCD1 -0.85 -6.8 -0.34 4.79e-11 Blood metabolite levels; LIHC cis rs4803468 0.935 rs13346603 chr19:41945837 T/A cg09537434 chr19:41945824 ATP5SL 1.02 21.14 0.75 4.72e-64 Height; LIHC cis rs36051895 0.623 rs1830610 chr9:5260079 C/T cg02405213 chr9:5042618 JAK2 -0.63 -10.6 -0.5 6.92e-23 Pediatric autoimmune diseases; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13559217 chr19:5119331 KDM4B 0.43 6.68 0.34 9.76e-11 Longevity; LIHC cis rs17685 0.712 rs7785025 chr7:75628101 C/T cg16489192 chr7:75678113 MDH2;STYXL1 0.36 5.96 0.31 6.14e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7100689 0.646 rs7081889 chr10:82165427 C/A cg01528321 chr10:82214614 TSPAN14 0.65 10.02 0.48 6.63e-21 Post bronchodilator FEV1; LIHC cis rs12291225 0.877 rs11023160 chr11:14264225 T/A cg19336497 chr11:14380999 RRAS2 -0.55 -10.31 -0.49 6.91e-22 Sense of smell; LIHC cis rs8062405 0.964 rs72793809 chr16:28832382 C/T cg00204512 chr16:28754710 NA 0.35 6.4 0.33 4.98e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg05185784 chr16:90016020 DEF8 0.45 5.84 0.3 1.19e-8 Skin colour saturation; LIHC cis rs36051895 0.664 rs7857081 chr9:5096728 G/A cg02405213 chr9:5042618 JAK2 -0.68 -11.72 -0.54 6.86e-27 Pediatric autoimmune diseases; LIHC cis rs55665837 0.540 rs11023302 chr11:14693935 C/G cg16394018 chr11:14927549 NA 0.4 5.72 0.3 2.27e-8 Vitamin D levels; LIHC cis rs10751667 0.666 rs7123912 chr11:963936 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.13 0.48 2.88e-21 Alzheimer's disease (late onset); LIHC cis rs7618501 0.521 rs2352984 chr3:49948728 T/C cg21467203 chr3:49911342 NA -0.58 -10.76 -0.5 1.96e-23 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.528 rs10496738 chr2:136751488 C/T cg25344623 chr2:136566232 LCT -0.37 -5.96 -0.31 6.45e-9 Corneal structure; LIHC cis rs644799 0.965 rs1944080 chr11:95503636 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.78 0.47 4.6e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4638749 0.734 rs6722745 chr2:108875244 C/T cg25838818 chr2:108905173 SULT1C2 0.41 7.4 0.37 1.1e-12 Blood pressure; LIHC cis rs9929218 0.953 rs11075696 chr16:68731365 A/G cg01231543 chr16:68741748 NA 0.38 5.89 0.3 9.02e-9 Colorectal cancer; LIHC cis rs875971 0.660 rs10272357 chr7:66063074 G/A cg11764359 chr7:65958608 NA -0.73 -10.96 -0.51 3.81e-24 Aortic root size; LIHC cis rs651907 0.514 rs12636046 chr3:101434448 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.51 0.49 1.45e-22 Colorectal cancer; LIHC cis rs3806843 0.735 rs778596 chr5:140037272 G/A cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs35110281 0.782 rs6518302 chr21:45018478 A/G cg04455712 chr21:45112962 RRP1B 0.48 8.2 0.41 4.97e-15 Mean corpuscular volume; LIHC cis rs16828019 0.852 rs3766324 chr1:41588653 A/G cg03962019 chr1:41807865 NA 0.52 7.49 0.38 6e-13 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 3.96e-13 Electroencephalogram traits; LIHC cis rs6546537 0.824 rs3771543 chr2:69784255 C/T cg10773587 chr2:69614142 GFPT1 -0.5 -6.81 -0.35 4.47e-11 Serum thyroid-stimulating hormone levels; LIHC cis rs60871478 0.787 rs4720928 chr7:808002 T/C cg13844804 chr7:814759 HEATR2 0.43 5.74 0.3 2.07e-8 Cerebrospinal P-tau181p levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20108328 chr21:46396156 C21orf70 -0.42 -6.26 -0.32 1.16e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg22974920 chr21:40686053 BRWD1 -0.41 -5.92 -0.3 7.72e-9 Cognitive function; LIHC cis rs473651 0.904 rs10929275 chr2:239323169 A/G cg21699342 chr2:239360505 ASB1 0.35 6.81 0.35 4.41e-11 Multiple system atrophy; LIHC trans rs1814175 0.817 rs10839318 chr11:49657511 G/C cg03929089 chr4:120376271 NA -0.89 -17.85 -0.69 8.1e-51 Height; LIHC cis rs6088580 0.608 rs8114616 chr20:32969092 G/T cg08999081 chr20:33150536 PIGU -0.62 -11.86 -0.54 2.01e-27 Glomerular filtration rate (creatinine); LIHC cis rs80282103 0.618 rs74117849 chr10:1165425 A/G cg08668510 chr10:1095578 IDI1 0.63 6.01 0.31 4.64e-9 Glomerular filtration rate (creatinine); LIHC cis rs7617773 0.780 rs11706277 chr3:48360433 A/G cg11946769 chr3:48343235 NME6 0.89 11.01 0.51 2.56e-24 Coronary artery disease; LIHC cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 12.2 0.55 1.19e-28 Platelet count; LIHC cis rs1008375 0.866 rs12233712 chr4:17570063 T/A cg02297831 chr4:17616191 MED28 0.47 6.98 0.35 1.53e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs877282 1.000 rs11253363 chr10:771891 A/G cg22713356 chr15:30763199 NA 1.36 12.27 0.55 6.54e-29 Uric acid levels; LIHC cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg11062466 chr8:58055876 NA 0.51 6.85 0.35 3.41e-11 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.875 rs7766463 chr6:146364453 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.8 -0.3 1.49e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs919433 0.889 rs6711624 chr2:198207607 C/G cg03934865 chr2:198174659 NA -0.56 -8.67 -0.42 1.74e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17331151 0.541 rs1139106 chr3:52871101 G/A cg04865290 chr3:52927548 TMEM110 -0.42 -6.34 -0.32 7.28e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs9858542 0.953 rs9841110 chr3:49492481 C/G cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00911488 chr4:106068604 TET2 0.44 6.23 0.32 1.35e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg10360139 chr7:1886902 MAD1L1 -0.4 -6.01 -0.31 4.74e-9 Bipolar disorder and schizophrenia; LIHC cis rs225245 0.791 rs4796103 chr17:34025182 A/G cg05299278 chr17:33885742 SLFN14 0.23 6.2 0.32 1.65e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC trans rs2243480 1.000 rs35058610 chr7:65390925 G/A cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg07341007 chr3:195489909 MUC4 0.45 7.87 0.39 4.76e-14 Lung disease severity in cystic fibrosis; LIHC cis rs35110281 0.774 rs1378080 chr21:45011315 T/A cg21573476 chr21:45109991 RRP1B -0.56 -10.64 -0.5 4.84e-23 Mean corpuscular volume; LIHC cis rs9858542 0.953 rs35169793 chr3:49423274 A/G cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs10883723 0.810 rs2296586 chr10:104245575 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 13.1 0.58 4.56e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg06466757 chr4:1255808 NA 0.34 5.77 0.3 1.76e-8 Obesity-related traits; LIHC cis rs6782228 0.585 rs9841161 chr3:128331870 A/G cg16766828 chr3:128327626 NA -0.41 -6.42 -0.33 4.62e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs617791 0.669 rs4994056 chr11:65750997 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.4 6.04 0.31 3.94e-9 Breast cancer; LIHC cis rs780096 0.565 rs10169261 chr2:27727314 C/T cg05484376 chr2:27715224 FNDC4 0.39 6.51 0.33 2.73e-10 Total body bone mineral density; LIHC cis rs8062405 0.964 rs62036614 chr16:28824685 T/C cg07451762 chr16:28383216 NA 0.36 6.66 0.34 1.07e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7131987 0.621 rs6487805 chr12:29457550 A/T cg14222432 chr12:29376421 FAR2 -0.35 -6.83 -0.35 3.79e-11 QT interval; LIHC cis rs6089584 0.586 rs1079755 chr20:60615262 G/A cg23262073 chr20:60523788 NA -0.28 -5.73 -0.3 2.21e-8 Body mass index; LIHC cis rs9467711 0.606 rs9379899 chr6:26603015 T/A cg09904177 chr6:26538194 HMGN4 -0.53 -5.72 -0.3 2.37e-8 Autism spectrum disorder or schizophrenia; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18268492 chr10:99185986 PGAM1 0.37 6.08 0.31 3.24e-9 Calcium levels; LIHC cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg08888203 chr3:10149979 C3orf24 -0.53 -6.39 -0.33 5.32e-10 Alzheimer's disease; LIHC cis rs6545883 0.931 rs778768 chr2:61790289 C/G cg15711740 chr2:61764176 XPO1 -0.43 -6.09 -0.31 3.05e-9 Tuberculosis; LIHC cis rs6933660 0.665 rs6921042 chr6:151732385 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.54 -8.23 -0.41 3.95e-15 Menarche (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19568834 chr20:34252926 CPNE1;RBM12 -0.54 -6.79 -0.34 4.9e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7412746 0.658 rs6660845 chr1:150841066 G/A cg17724175 chr1:150552817 MCL1 0.47 9.08 0.44 8.87e-18 Melanoma; LIHC cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.45 -0.37 7.75e-13 Bipolar disorder; LIHC cis rs13190036 0.748 rs28395268 chr5:176710547 C/G cg06733329 chr5:176740039 MXD3 -0.36 -6.17 -0.32 1.94e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs55665837 0.701 rs11023265 chr11:14616038 C/T cg25251204 chr11:14927456 NA 0.43 6.01 0.31 4.84e-9 Vitamin D levels; LIHC cis rs5753618 0.561 rs2283881 chr22:31638932 G/A cg22777020 chr22:31556080 RNF185 -0.55 -6.31 -0.32 8.59e-10 Colorectal cancer; LIHC cis rs67311347 1.000 rs4974017 chr3:40473519 C/T cg09455208 chr3:40491958 NA 0.34 6.94 0.35 1.97e-11 Renal cell carcinoma; LIHC cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg18876405 chr7:65276391 NA 0.56 9.36 0.45 1.1e-18 Aortic root size; LIHC cis rs75920871 0.588 rs3181 chr11:116907043 C/T cg01368799 chr11:117014884 PAFAH1B2 -0.44 -5.72 -0.3 2.36e-8 Subjective well-being; LIHC cis rs4853012 0.838 rs4563249 chr2:74354016 G/T cg20891558 chr2:74357851 NA 0.8 17.07 0.68 1.06e-47 Gestational age at birth (maternal effect); LIHC cis rs77633900 0.772 rs284897 chr15:76750722 T/C cg21673338 chr15:77095150 SCAPER -0.51 -5.95 -0.31 6.51e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs7903847 0.642 rs10882914 chr10:99142057 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs2243480 1.000 rs160643 chr7:65558222 C/T cg10756647 chr7:56101905 PSPH 0.96 12.22 0.55 9.5e-29 Diabetic kidney disease; LIHC cis rs7618915 0.781 rs12489732 chr3:52566820 C/A cg18404041 chr3:52824283 ITIH1 -0.51 -7.88 -0.39 4.32e-14 Bipolar disorder; LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg00656387 chr3:40428638 ENTPD3 0.5 8.39 0.41 1.34e-15 Renal cell carcinoma; LIHC cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg08499158 chr17:42289980 UBTF 0.53 8.49 0.42 6.31e-16 Total body bone mineral density; LIHC cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg11644478 chr21:40555479 PSMG1 -0.38 -6.08 -0.31 3.13e-9 Menarche (age at onset); LIHC cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg03806693 chr22:41940476 POLR3H -0.98 -11.22 -0.52 4.21e-25 Vitiligo; LIHC trans rs61931739 0.500 rs10772154 chr12:34373271 A/C cg26384229 chr12:38710491 ALG10B 0.59 7.54 0.38 4.35e-13 Morning vs. evening chronotype; LIHC cis rs7937890 0.874 rs2303972 chr11:14303282 T/A cg23387056 chr11:14280742 SPON1 0.46 6.3 0.32 9.28e-10 Mitochondrial DNA levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15742519 chr2:190627263 OSGEPL1 0.54 7.34 0.37 1.59e-12 Lung function (FEV1/FVC); LIHC cis rs7829975 0.593 rs2921077 chr8:8304502 C/T cg15556689 chr8:8085844 FLJ10661 0.44 6.84 0.35 3.72e-11 Mood instability; LIHC cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg01788221 chr16:89496183 ANKRD11 -0.38 -5.98 -0.31 5.74e-9 Multiple myeloma (IgH translocation); LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg03395511 chr6:291903 DUSP22 -0.53 -7.34 -0.37 1.57e-12 Menopause (age at onset); LIHC cis rs72781680 0.821 rs55948613 chr2:24094787 A/G cg08917208 chr2:24149416 ATAD2B 0.64 6.55 0.33 2.09e-10 Lymphocyte counts; LIHC trans rs1814175 0.817 rs10839397 chr11:49857074 C/T cg03929089 chr4:120376271 NA -0.9 -18.64 -0.71 5.02e-54 Height; LIHC cis rs10847980 0.590 rs12319654 chr12:123327160 C/T cg18912006 chr12:123335444 HIP1R 0.76 7.79 0.39 8.13e-14 Adiponectin levels; LIHC cis rs6570726 0.755 rs2092297 chr6:145893765 A/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.38 -0.33 5.68e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10792665 0.541 rs10898050 chr11:82593525 C/T cg24227371 chr11:82718527 RAB30 -0.28 -6.68 -0.34 9.5e-11 Obesity-related traits; LIHC cis rs3815308 0.530 rs2240129 chr19:2197734 C/T cg09261902 chr19:2140048 AP3D1 0.37 6.37 0.33 6.19e-10 Breast cancer; LIHC cis rs6752107 0.936 rs6431660 chr2:234167234 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.16 0.4 6.27e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs72627123 0.867 rs73303122 chr14:74486797 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.68 0.46 9.74e-20 Morning vs. evening chronotype; LIHC cis rs7487075 0.930 rs4076484 chr12:46833912 C/G cg22049899 chr12:47219821 SLC38A4 0.32 5.8 0.3 1.5e-8 Itch intensity from mosquito bite; LIHC cis rs950169 0.922 rs11639244 chr15:84832650 G/A cg12863693 chr15:85201151 NMB 0.4 5.86 0.3 1.08e-8 Schizophrenia; LIHC cis rs4407350 0.868 rs5765719 chr22:44917849 A/G cg26276947 chr22:44892394 LDOC1L 0.34 6.4 0.33 4.99e-10 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.64 0.34 1.25e-10 Bipolar disorder; LIHC cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg18305652 chr10:134549665 INPP5A 0.44 6.47 0.33 3.38e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs738321 0.757 rs4821748 chr22:38541936 G/A cg25457927 chr22:38595422 NA -0.35 -7.84 -0.39 5.64e-14 Breast cancer; LIHC cis rs8014204 0.604 rs2159906 chr14:75390912 G/T cg08847533 chr14:75593920 NEK9 0.45 7.25 0.37 2.72e-12 Caffeine consumption; LIHC cis rs10504073 0.647 rs9643394 chr8:50014427 A/G cg00325661 chr8:49890786 NA 0.31 7.13 0.36 6.13e-12 Blood metabolite ratios; LIHC cis rs6893300 0.524 rs12522926 chr5:179214818 G/A cg14593053 chr5:179126677 CANX 0.44 7.83 0.39 5.99e-14 Resting heart rate; LIHC cis rs6748734 0.553 rs7340215 chr2:241805851 A/G cg04034577 chr2:241836375 C2orf54 -0.29 -6.07 -0.31 3.33e-9 Urinary metabolites; LIHC cis rs17401966 0.931 rs2276100 chr1:10394536 C/G cg15208524 chr1:10270712 KIF1B 0.42 6.22 0.32 1.43e-9 Hepatocellular carcinoma; LIHC cis rs2637266 1.000 rs7897015 chr10:78366566 G/C cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.57 0.46 2.14e-19 Intelligence (multi-trait analysis); LIHC cis rs732505 0.717 rs3213651 chr19:5593771 A/G cg26242866 chr19:5711310 LONP1 0.89 6.54 0.33 2.3e-10 vWF and FVIII levels; LIHC cis rs12477438 0.501 rs11685756 chr2:99766215 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.38 0.59 3.85e-33 Chronic sinus infection; LIHC cis rs644799 0.672 rs11021307 chr11:95501407 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.79 12.04 0.55 4.52e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9393692 0.572 rs4145878 chr6:26198046 A/T cg18357526 chr6:26021779 HIST1H4A 0.45 6.19 0.32 1.77e-9 Educational attainment; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs9942416 0.660 rs1817869 chr5:74989037 T/C cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs4930103 0.935 rs2525881 chr11:2019333 T/C cg06197492 chr11:2016605 H19 0.38 6.05 0.31 3.76e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg12310025 chr6:25882481 NA -0.66 -8.22 -0.41 4.31e-15 Intelligence (multi-trait analysis); LIHC cis rs7666738 0.830 rs13108871 chr4:98803872 T/C cg05340658 chr4:99064831 C4orf37 0.64 11.79 0.54 3.74e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs12744310 1.000 rs55929643 chr1:41774212 A/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg25204440 chr1:209979598 IRF6 0.51 7.83 0.39 6.21e-14 Cleft lip with or without cleft palate; LIHC cis rs35306767 0.953 rs35693858 chr10:979813 C/T cg20503657 chr10:835505 NA 0.89 9.78 0.47 4.56e-20 Eosinophil percentage of granulocytes; LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs6088590 0.561 rs6059934 chr20:33178324 G/T cg08999081 chr20:33150536 PIGU 0.7 13.8 0.6 9.69e-35 Coronary artery disease; LIHC cis rs7520050 0.966 rs7550746 chr1:46351719 T/A cg03146154 chr1:46216737 IPP -0.4 -6.51 -0.33 2.66e-10 Red blood cell count;Reticulocyte count; LIHC cis rs644799 1.000 rs10831431 chr11:95510089 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.69 10.01 0.48 7.51e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs6759952 0.649 rs1382435 chr2:218296003 A/G cg06115535 chr2:131100015 IMP4;CCDC115 0.43 6.06 0.31 3.55e-9 Thyroid cancer; LIHC cis rs11951515 0.508 rs10065689 chr5:43604258 T/C cg01983248 chr5:43482804 C5orf28 -0.4 -6.48 -0.33 3.12e-10 Metabolite levels (X-11787); LIHC cis rs9918079 0.560 rs4698409 chr4:15659766 G/A cg21329975 chr4:15471214 CC2D2A -0.4 -6.04 -0.31 4.05e-9 Obesity-related traits; LIHC cis rs7927771 0.524 rs1563820 chr11:47833398 A/T cg20307385 chr11:47447363 PSMC3 -0.66 -9.97 -0.47 1.01e-20 Subjective well-being; LIHC cis rs10883723 0.775 rs2296579 chr10:104241375 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.58 0.56 4.5e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg02359409 chr6:42947317 PEX6 0.52 7.33 0.37 1.68e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2302190 0.882 rs8072873 chr17:56669049 G/C cg12560992 chr17:57184187 TRIM37 0.69 8.91 0.43 3.17e-17 Vitamin D levels; LIHC cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -13.94 -0.6 2.78e-35 Alzheimer's disease; LIHC cis rs2625529 0.824 rs4776586 chr15:72430503 C/A cg16672083 chr15:72433130 SENP8 -0.31 -5.97 -0.31 6.09e-9 Red blood cell count; LIHC cis rs77216612 0.835 rs10845621 chr12:12887977 C/T cg04607235 chr12:12878440 APOLD1 -0.98 -15.91 -0.65 4.65e-43 Lymphocyte counts; LIHC cis rs2066819 1.000 rs57870697 chr12:56752874 A/G cg26714650 chr12:56694279 CS -1.35 -12.74 -0.57 1.09e-30 Psoriasis vulgaris; LIHC cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg11890956 chr21:40555474 PSMG1 -0.5 -8.33 -0.41 2e-15 Menarche (age at onset); LIHC cis rs35883536 1.000 rs2297712 chr1:101092813 C/T cg14515779 chr1:101123966 NA -0.67 -12.97 -0.57 1.47e-31 Monocyte count; LIHC cis rs10504229 0.679 rs1442125 chr8:58036258 A/C cg02290350 chr8:58132656 NA -0.33 -7.88 -0.39 4.3e-14 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs4850891 chr2:99574642 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.07 -14.9 -0.63 4.91e-39 Chronic sinus infection; LIHC cis rs1707322 0.963 rs6690652 chr1:46376692 G/T cg06784218 chr1:46089804 CCDC17 0.34 6.09 0.31 3.11e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4975709 0.589 rs4975746 chr5:1861069 G/A cg14773178 chr5:1868261 NA 0.27 7.14 0.36 5.49e-12 Cardiovascular disease risk factors; LIHC cis rs11764590 0.715 rs11760737 chr7:2104055 T/C cg23422044 chr7:1970798 MAD1L1 -0.5 -5.71 -0.3 2.42e-8 Neuroticism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24051152 chr8:145133159 EXOSC4 0.56 8.07 0.4 1.23e-14 Pancreatic cancer; LIHC cis rs11583043 0.918 rs11581062 chr1:101407519 C/T cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.5 -6.31 -0.32 8.58e-10 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg20887711 chr4:1340912 KIAA1530 0.45 6.01 0.31 4.84e-9 Obesity-related traits; LIHC cis rs7592578 0.771 rs75579212 chr2:191376575 C/T cg27211696 chr2:191398769 TMEM194B -0.61 -8.07 -0.4 1.23e-14 Diastolic blood pressure; LIHC cis rs4474465 0.646 rs10793337 chr11:78285875 A/T cg02023728 chr11:77925099 USP35 -0.32 -5.77 -0.3 1.82e-8 Alzheimer's disease (survival time); LIHC cis rs10186029 0.648 rs13022006 chr2:213940309 A/C cg08319019 chr2:214017104 IKZF2 0.41 5.85 0.3 1.13e-8 Systemic sclerosis; LIHC trans rs1814175 0.645 rs10742953 chr11:49807491 C/G cg15704280 chr7:45808275 SEPT13 0.95 19.21 0.72 2.72e-56 Height; LIHC cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg11062466 chr8:58055876 NA 0.39 5.72 0.3 2.34e-8 Developmental language disorder (linguistic errors); LIHC cis rs9649465 0.967 rs6950373 chr7:123361773 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.15e-15 Migraine; LIHC cis rs8062405 0.755 rs4787455 chr16:28589455 G/A cg07451762 chr16:28383216 NA 0.38 6.76 0.34 6.11e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4268898 0.760 rs55863105 chr2:24570695 C/T cg06627628 chr2:24431161 ITSN2 0.45 6.43 0.33 4.36e-10 Asthma; LIHC cis rs7582720 0.945 rs72934601 chr2:204031137 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs11122272 0.525 rs61835222 chr1:231537917 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -10.34 -0.49 5.53e-22 Hemoglobin concentration; LIHC trans rs1005277 0.505 rs200937 chr10:38135772 T/C cg17830980 chr10:43048298 ZNF37B -0.46 -8.85 -0.43 4.65e-17 Extrinsic epigenetic age acceleration; LIHC cis rs17253792 0.822 rs10083431 chr14:56068348 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg01765077 chr12:122356316 WDR66 0.57 7.68 0.38 1.73e-13 Mean corpuscular volume; LIHC cis rs6088590 0.735 rs6060001 chr20:33294353 C/T cg24642439 chr20:33292090 TP53INP2 -0.59 -8.47 -0.42 7.31e-16 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01774158 chr5:133562094 PPP2CA 0.6 7.76 0.39 9.76e-14 Lung function (FEV1/FVC); LIHC cis rs2404602 0.692 rs1116535 chr15:77009514 C/G cg03037974 chr15:76606532 NA -0.73 -14.43 -0.62 3.34e-37 Blood metabolite levels; LIHC cis rs918629 0.530 rs7702674 chr5:95237365 A/C cg10483112 chr5:95245456 ELL2 -0.36 -6.52 -0.33 2.46e-10 IgG glycosylation; LIHC cis rs11190604 0.767 rs74869390 chr10:102189385 A/G cg07080220 chr10:102295463 HIF1AN 0.47 6.87 0.35 2.96e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.96 0.31 6.25e-9 Menopause (age at onset); LIHC trans rs916888 0.821 rs199507 chr17:44858855 A/G cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2067615 0.524 rs10778503 chr12:107090616 C/T cg15890332 chr12:107067104 RFX4 0.27 6.35 0.32 6.99e-10 Heart rate; LIHC cis rs9534288 0.797 rs7990095 chr13:46587262 G/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs3770081 1.000 rs78650586 chr2:86190783 G/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -7.84 -0.39 5.88e-14 Facial emotion recognition (sad faces); LIHC cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg18230493 chr5:56204884 C5orf35 -0.46 -6.41 -0.33 4.94e-10 Initial pursuit acceleration; LIHC cis rs6504950 0.800 rs9907961 chr17:53012927 C/G cg10237252 chr17:52977213 TOM1L1 -0.34 -5.99 -0.31 5.22e-9 Breast cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01270466 chr14:96506401 C14orf132 -0.38 -6.08 -0.31 3.27e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs6578985 0.741 rs10840366 chr11:2124435 C/A cg20230732 chr3:128721448 CCDC48 0.37 6.09 0.31 3.05e-9 Femoral neck bone geometry and menarche (age at onset); LIHC cis rs7552404 0.824 rs1251079 chr1:76189445 C/T cg10523679 chr1:76189770 ACADM 0.69 14.53 0.62 1.37e-37 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg02475777 chr4:1388615 CRIPAK 0.57 8.52 0.42 5.29e-16 Longevity; LIHC cis rs1728785 1.000 rs1728792 chr16:68596534 G/C cg02972257 chr16:68554789 NA -0.55 -6.21 -0.32 1.55e-9 Ulcerative colitis; LIHC cis rs7258465 1.000 rs34746918 chr19:18539744 C/T cg10790698 chr19:18539756 SSBP4 -0.37 -7.53 -0.38 4.47e-13 Breast cancer; LIHC cis rs2050392 0.517 rs7096279 chr10:30759608 C/T cg25182066 chr10:30743637 MAP3K8 -0.64 -10.5 -0.49 1.48e-22 Inflammatory bowel disease; LIHC cis rs8062405 1.000 rs4788102 chr16:28873398 G/A cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22649068 chr1:150552352 MCL1 0.43 6.07 0.31 3.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.7 9.94 0.47 1.26e-20 Lymphocyte counts; LIHC cis rs965469 0.947 rs6051773 chr20:3330382 C/G cg25506879 chr20:3388711 C20orf194 -0.57 -6.88 -0.35 2.95e-11 IFN-related cytopenia; LIHC cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg22508957 chr16:3507546 NAT15 0.49 8.49 0.42 6.48e-16 Tuberculosis; LIHC cis rs72772090 0.710 rs11750400 chr5:96077968 A/T cg17330273 chr5:96107758 CAST;ERAP1 -0.64 -7.26 -0.37 2.71e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg10755058 chr3:40428713 ENTPD3 0.41 6.89 0.35 2.77e-11 Renal cell carcinoma; LIHC cis rs9733 0.519 rs1134067 chr1:150721175 G/T cg15448220 chr1:150897856 SETDB1 0.42 6.47 0.33 3.44e-10 Tonsillectomy; LIHC cis rs1865760 1.000 rs6938233 chr6:25914077 C/T cg17691542 chr6:26056736 HIST1H1C 0.38 5.79 0.3 1.58e-8 Height; LIHC cis rs4713118 0.869 rs6902689 chr6:27709441 C/T cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs4689592 0.503 rs10516184 chr4:7060959 C/T cg19539972 chr4:7069911 GRPEL1 0.7 9.83 0.47 3.1e-20 Monocyte percentage of white cells; LIHC cis rs2806561 0.765 rs2806565 chr1:23507068 A/G cg19743168 chr1:23544995 NA 0.34 5.81 0.3 1.39e-8 Height; LIHC cis rs2404602 0.647 rs12903586 chr15:77168240 G/A cg03037974 chr15:76606532 NA -0.6 -10.09 -0.48 4.04e-21 Blood metabolite levels; LIHC cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg21280719 chr6:42927975 GNMT -0.32 -7.5 -0.38 5.65e-13 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4788570 0.697 rs9635524 chr16:71804956 C/G cg06353428 chr16:71660113 MARVELD3 1.32 14.19 0.61 2.88e-36 Intelligence (multi-trait analysis); LIHC cis rs936229 0.749 rs6495126 chr15:75175026 C/T cg14664628 chr15:75095509 CSK 0.71 9.49 0.46 4.02e-19 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs897984 0.568 rs56083427 chr16:30881298 C/T cg02466173 chr16:30829666 NA -0.44 -6.71 -0.34 8.16e-11 Dementia with Lewy bodies; LIHC trans rs1814175 0.781 rs12286395 chr11:49954062 C/G cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg12311346 chr5:56204834 C5orf35 -0.48 -6.29 -0.32 9.7e-10 Initial pursuit acceleration; LIHC cis rs963731 0.649 rs78510010 chr2:39348662 T/C cg04010122 chr2:39346883 SOS1 0.69 6.06 0.31 3.62e-9 Corticobasal degeneration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01111842 chr9:140444966 PNPLA7;MRPL41 0.45 6.27 0.32 1.12e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs4927850 0.881 rs7624638 chr3:195748729 C/T cg21051086 chr3:73046214 PPP4R2 -0.38 -6.1 -0.31 2.83e-9 Pancreatic cancer; LIHC cis rs7107174 1.000 rs2512532 chr11:77968641 T/C cg02023728 chr11:77925099 USP35 0.49 9.4 0.45 8.01e-19 Testicular germ cell tumor; LIHC cis rs17685 0.775 rs11761172 chr7:75761547 C/T cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2404602 0.669 rs17464903 chr15:77195486 A/G cg23625390 chr15:77176239 SCAPER 0.36 5.85 0.3 1.16e-8 Blood metabolite levels; LIHC trans rs4650994 1.000 rs4650999 chr1:178532188 A/C cg05059571 chr16:84539110 KIAA1609 0.38 6.4 0.33 5.12e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs916888 0.821 rs199504 chr17:44861003 C/T cg01570182 chr17:44337453 NA -1.0 -9.98 -0.47 9.46e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2637030 0.559 rs2607501 chr5:52989545 A/T cg06476337 chr5:52856530 NDUFS4 0.42 6.75 0.34 6.4e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20783262 chr1:68152310 GADD45A 0.46 6.38 0.33 5.72e-10 Lung function (FEV1/FVC); LIHC cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 5.96 0.31 6.24e-9 Schizophrenia; LIHC cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.25e-12 Bipolar disorder; LIHC cis rs12986413 1.000 rs11882273 chr19:2173836 T/C cg09261902 chr19:2140048 AP3D1 0.37 6.38 0.33 5.85e-10 Height; LIHC cis rs1552244 0.626 rs2886396 chr3:10037670 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs208520 0.565 rs1385222 chr6:66753013 C/T cg07460842 chr6:66804631 NA 0.82 14.6 0.62 7.36e-38 Exhaled nitric oxide output; LIHC cis rs7586673 0.964 rs34444368 chr2:161954217 G/A cg16506815 chr2:162101123 NA 0.48 7.74 0.39 1.14e-13 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg22800045 chr5:56110881 MAP3K1 0.58 6.94 0.35 2e-11 Initial pursuit acceleration; LIHC cis rs700651 0.754 rs1518367 chr2:198807015 T/A cg00792783 chr2:198669748 PLCL1 0.45 6.63 0.34 1.33e-10 Intracranial aneurysm; LIHC cis rs847649 0.692 rs10279449 chr7:102462636 T/C cg18108683 chr7:102477205 FBXL13 -0.52 -8.04 -0.4 1.53e-14 Morning vs. evening chronotype; LIHC cis rs12477438 0.501 rs13000731 chr2:99795231 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs1113500 0.836 rs1539553 chr1:108589998 C/T cg06207961 chr1:108661230 NA -0.37 -7.5 -0.38 5.63e-13 Growth-regulated protein alpha levels; LIHC cis rs10504229 0.861 rs67966192 chr8:58188172 A/C cg20607798 chr8:58055168 NA 0.46 5.88 0.3 9.86e-9 Developmental language disorder (linguistic errors); LIHC cis rs7223966 1.000 rs7217982 chr17:61832150 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 7.08 0.36 7.99e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg08392591 chr16:89556376 ANKRD11 0.51 8.15 0.4 6.8e-15 Multiple myeloma (IgH translocation); LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg26378183 chr14:73924401 NUMB 0.44 6.26 0.32 1.14e-9 Gut microbiome composition (summer); LIHC cis rs6754311 0.731 rs6719488 chr2:136575199 G/T cg07305463 chr2:136567211 LCT 0.39 7.54 0.38 4.34e-13 Mosquito bite size; LIHC cis rs929354 0.772 rs1182362 chr7:157019535 A/G cg05182265 chr7:156933206 UBE3C 0.33 6.3 0.32 9.38e-10 Body mass index; LIHC cis rs6964587 1.000 rs7785095 chr7:91640773 A/T cg17063962 chr7:91808500 NA -1.0 -19.39 -0.72 4.95e-57 Breast cancer; LIHC cis rs7020830 0.931 rs7027473 chr9:37132462 A/G cg14294708 chr9:37120828 ZCCHC7 1.19 28.2 0.84 3.06e-91 Schizophrenia; LIHC cis rs7208859 0.673 rs9903862 chr17:29206433 G/A cg14067834 chr17:29058358 SUZ12P 0.74 6.97 0.35 1.68e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1728785 0.892 rs4783562 chr16:68562963 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.04 0.31 4.11e-9 Ulcerative colitis; LIHC cis rs17685 0.753 rs11982200 chr7:75714883 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1814175 0.616 rs4881723 chr11:49788566 G/T cg03929089 chr4:120376271 NA -0.84 -15.93 -0.65 3.87e-43 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09133386 chr6:20404188 E2F3 0.41 6.55 0.33 2.07e-10 Cognitive function; LIHC cis rs9611565 0.592 rs5996039 chr22:41981957 A/G cg06634786 chr22:41940651 POLR3H -0.56 -5.92 -0.3 7.82e-9 Vitiligo; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg07677032 chr17:61819896 STRADA 0.42 6.1 0.31 2.82e-9 Prudent dietary pattern; LIHC cis rs11233413 0.532 rs2374349 chr11:82670073 A/G cg24227371 chr11:82718527 RAB30 -0.3 -6.65 -0.34 1.19e-10 Economic and political preferences (feminism/equality); LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg04013166 chr16:89971882 TCF25 0.59 7.84 0.39 5.79e-14 Skin colour saturation; LIHC cis rs919433 0.679 rs9967823 chr2:198531529 A/G cg03934865 chr2:198174659 NA 0.43 6.23 0.32 1.34e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs28456 1 rs28456 chr11:61589481 A/G cg07689907 chr11:61582574 FADS1 0.4 5.79 0.3 1.6e-8 Bipolar disorder; LIHC cis rs1707322 0.963 rs10890373 chr1:46393755 A/C cg06784218 chr1:46089804 CCDC17 0.37 6.58 0.34 1.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17685 0.816 rs11763076 chr7:75765963 C/T cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7107174 0.901 rs4944199 chr11:78122779 A/G cg02023728 chr11:77925099 USP35 0.35 6.46 0.33 3.59e-10 Testicular germ cell tumor; LIHC cis rs13161895 1.000 rs27018 chr5:179405144 A/G cg06664874 chr5:179499304 RNF130 0.57 6.99 0.35 1.48e-11 LDL cholesterol; LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg16358155 chr3:195490169 MUC4 0.44 6.7 0.34 8.39e-11 Lung disease severity in cystic fibrosis; LIHC cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg07061783 chr6:25882402 NA -0.44 -6.16 -0.32 2.06e-9 Blood metabolite levels; LIHC cis rs12048904 0.595 rs2295280 chr1:101342497 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.72 12.59 0.56 4.08e-30 Multiple sclerosis; LIHC cis rs963731 0.649 rs297135 chr2:39304793 G/A cg04010122 chr2:39346883 SOS1 -0.71 -6.33 -0.32 7.56e-10 Corticobasal degeneration; LIHC cis rs8067354 0.507 rs2645478 chr17:58014712 G/A cg13753209 chr17:57696993 CLTC 0.7 10.49 0.49 1.66e-22 Hemoglobin concentration; LIHC trans rs1005277 0.579 rs176880 chr10:38401417 C/G cg17830980 chr10:43048298 ZNF37B 0.55 11.19 0.52 5.65e-25 Extrinsic epigenetic age acceleration; LIHC cis rs5769707 0.681 rs1107514 chr22:50042383 T/C cg07959070 chr22:50026188 C22orf34 -0.34 -8.29 -0.41 2.66e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1707322 1.000 rs4660895 chr1:46329739 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs965469 1.000 rs6051764 chr20:3321807 A/G cg25506879 chr20:3388711 C20orf194 0.47 5.86 0.3 1.09e-8 IFN-related cytopenia; LIHC cis rs11098499 0.954 rs10008392 chr4:120318839 G/A cg09307838 chr4:120376055 NA 0.76 11.87 0.54 1.83e-27 Corneal astigmatism; LIHC cis rs11792861 0.962 rs11789624 chr9:111796231 T/C cg13535736 chr9:111863775 C9orf5 -0.41 -6.26 -0.32 1.16e-9 Menarche (age at onset); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg10715820 chr1:17235063 NA 0.43 6.76 0.34 6e-11 Bilirubin levels; LIHC cis rs10463316 0.925 rs6877344 chr5:150742650 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -6.05 -0.31 3.9e-9 Metabolite levels (Pyroglutamine); LIHC cis rs12701220 0.503 rs12702024 chr7:1129820 G/C cg00990874 chr7:1149470 C7orf50 -0.58 -5.81 -0.3 1.44e-8 Bronchopulmonary dysplasia; LIHC cis rs9902453 0.934 rs12453172 chr17:28441590 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.89 0.47 1.92e-20 Coffee consumption (cups per day); LIHC cis rs12644436 0.628 rs10776486 chr4:88782517 A/G cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16725865 chr1:92546135 BTBD8 0.46 7.93 0.39 3.15e-14 Cognitive function; LIHC cis rs8067545 0.616 rs203470 chr17:19858626 C/T cg13482628 chr17:19912719 NA 0.39 6.42 0.33 4.51e-10 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01125608 chr5:646071 CEP72 0.46 6.71 0.34 8.04e-11 Longevity; LIHC cis rs9309473 1.000 rs7580825 chr2:73635148 G/A cg20560298 chr2:73613845 ALMS1 -0.59 -6.85 -0.35 3.4e-11 Metabolite levels; LIHC cis rs4700695 0.719 rs27078 chr5:65445331 G/C cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.46e-15 Facial morphology (factor 19); LIHC cis rs1023500 0.596 rs5751204 chr22:42433801 C/T cg15557168 chr22:42548783 NA -0.42 -6.55 -0.33 2.1e-10 Schizophrenia; LIHC cis rs9914988 0.943 rs9891925 chr17:27104540 A/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs600806 0.850 rs1343465 chr1:109937426 T/C cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs6964587 1.000 rs7784248 chr7:91758111 A/G cg17063962 chr7:91808500 NA 1.01 19.44 0.72 3.13e-57 Breast cancer; LIHC cis rs75908454 1.000 rs79721653 chr6:169903083 T/A cg19338460 chr6:170058176 WDR27 -0.8 -7.26 -0.37 2.57e-12 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs7264396 0.635 rs6060673 chr20:34482396 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.65 10.58 0.5 8.38e-23 Total cholesterol levels; LIHC cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg14004847 chr7:1930337 MAD1L1 -0.48 -6.83 -0.35 3.78e-11 Bipolar disorder and schizophrenia; LIHC cis rs1577917 0.652 rs75593931 chr6:86719539 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.16 -0.48 2.32e-21 Response to antipsychotic treatment; LIHC cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs11676348 0.774 rs13397673 chr2:219047782 A/G cg00012203 chr2:219082015 ARPC2 -0.48 -6.4 -0.33 5.26e-10 Ulcerative colitis; LIHC cis rs79149102 0.579 rs59303424 chr15:75370014 G/A cg16226627 chr15:75307476 SCAMP5 0.49 8.62 0.42 2.57e-16 Lung cancer; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg18538332 chr22:24372958 LOC391322 0.54 7.57 0.38 3.44e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg05890377 chr2:74357713 NA 0.63 12.8 0.57 6.46e-31 Gestational age at birth (maternal effect); LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg11494091 chr17:61959527 GH2 0.43 7.83 0.39 6.36e-14 Prudent dietary pattern; LIHC cis rs908922 0.676 rs2282296 chr1:152487979 C/T cg20991723 chr1:152506922 NA 0.58 10.21 0.48 1.59e-21 Hair morphology; LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg16822855 chr3:40428330 ENTPD3 0.33 5.96 0.31 6.43e-9 Renal cell carcinoma; LIHC cis rs1023500 0.573 rs8135801 chr22:42475568 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.38 -6.06 -0.31 3.64e-9 Schizophrenia; LIHC cis rs778371 0.676 rs7560115 chr2:233709465 T/G cg08000102 chr2:233561755 GIGYF2 -0.77 -9.35 -0.45 1.18e-18 Schizophrenia; LIHC cis rs526821 0.595 rs2926309 chr11:55314219 G/A cg04317927 chr11:55418816 OR4S2 0.47 9.04 0.44 1.17e-17 Pediatric bone mineral density (spine); LIHC trans rs10805346 0.531 rs12498927 chr4:10115523 C/T cg06175025 chr14:78082992 SPTLC2 0.46 6.7 0.34 8.34e-11 Urate levels in overweight individuals;Urate levels in obese individuals; LIHC cis rs9902453 0.967 rs8082175 chr17:28430303 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.65 10.06 0.48 4.93e-21 Coffee consumption (cups per day); LIHC cis rs28374715 0.662 rs11852419 chr15:41456374 A/T cg18705301 chr15:41695430 NDUFAF1 0.81 8.98 0.44 1.89e-17 Ulcerative colitis; LIHC cis rs909002 0.849 rs871634 chr1:32093167 G/C cg13919466 chr1:32135498 COL16A1 -0.31 -5.98 -0.31 5.64e-9 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs11161515 chr1:76212559 C/T cg03433033 chr1:76189801 ACADM 0.66 9.27 0.45 2.12e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7224737 0.750 rs13380830 chr17:40297658 C/G cg20291162 chr17:40259547 DHX58 -0.42 -5.94 -0.31 7.2e-9 Fibrinogen levels; LIHC cis rs8016982 0.698 rs12590764 chr14:81704417 G/A cg01989461 chr14:81687754 GTF2A1 0.64 12.9 0.57 2.62e-31 Schizophrenia; LIHC cis rs12594515 1.000 rs8032835 chr15:45997897 C/G cg01629716 chr15:45996671 NA 0.51 9.21 0.45 3.44e-18 Waist circumference;Weight; LIHC cis rs17102423 0.768 rs8005829 chr14:65576165 C/T cg16583315 chr14:65563665 MAX 0.42 8.42 0.41 1.02e-15 Obesity-related traits; LIHC cis rs8067354 0.681 rs9907923 chr17:57824927 C/T cg02344993 chr17:57696989 CLTC 0.7 11.89 0.54 1.66e-27 Hemoglobin concentration; LIHC cis rs7592578 0.771 rs12053190 chr2:191383348 A/G cg10560079 chr2:191398806 TMEM194B -0.83 -12.1 -0.55 2.62e-28 Diastolic blood pressure; LIHC cis rs7539624 0.588 rs61823966 chr1:223895942 C/T cg07395969 chr1:223900822 CAPN2 0.49 5.77 0.3 1.82e-8 Schizophrenia; LIHC cis rs7772486 0.686 rs9390349 chr6:146054430 T/G cg13319975 chr6:146136371 FBXO30 0.34 5.73 0.3 2.25e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.619 rs10278371 chr7:66051540 C/A cg18876405 chr7:65276391 NA -0.47 -8.02 -0.4 1.76e-14 Aortic root size; LIHC cis rs933688 1.000 rs6862125 chr5:90724598 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 21.47 0.76 2.25e-65 Smoking behavior; LIHC cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg06238570 chr21:40685208 BRWD1 0.6 7.09 0.36 7.97e-12 Cognitive function; LIHC cis rs1552244 0.572 rs3894323 chr3:10168967 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs4700695 0.668 rs36837 chr5:65480007 C/A cg21114390 chr5:65439923 SFRS12 -0.58 -8.24 -0.41 3.74e-15 Facial morphology (factor 19); LIHC cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg12903224 chr12:29470962 FAR2 -0.41 -6.47 -0.33 3.39e-10 QT interval; LIHC cis rs67311347 0.866 rs9826419 chr3:40352051 G/A cg09455208 chr3:40491958 NA 0.33 6.24 0.32 1.32e-9 Renal cell carcinoma; LIHC cis rs507080 0.922 rs12788848 chr11:118553788 C/T cg04173919 chr11:118528438 PHLDB1 0.33 6.24 0.32 1.33e-9 Serum metabolite levels; LIHC cis rs12744310 1.000 rs60825180 chr1:41771744 A/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11122272 0.735 rs2486745 chr1:231505717 T/C cg06096015 chr1:231504339 EGLN1 0.48 8.64 0.42 2.17e-16 Hemoglobin concentration; LIHC cis rs950169 0.509 rs71395455 chr15:85153804 A/G cg03959625 chr15:84868606 LOC388152 0.42 5.76 0.3 1.87e-8 Schizophrenia; LIHC cis rs10463316 0.817 rs6879238 chr5:150820574 G/C cg03212797 chr5:150827313 SLC36A1 -0.41 -6.1 -0.31 2.92e-9 Metabolite levels (Pyroglutamine); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23002097 chr19:58898625 RPS5 -0.44 -6.63 -0.34 1.3e-10 Cognitive function; LIHC trans rs916888 0.773 rs199445 chr17:44817408 C/T cg16836995 chr17:43662488 NA -0.74 -7.65 -0.38 2e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6442522 0.644 rs6783160 chr3:15509018 C/T cg16303742 chr3:15540471 COLQ 0.46 7.81 0.39 6.93e-14 Uric acid levels; LIHC cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg27297192 chr10:134578999 INPP5A 0.56 7.71 0.38 1.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg19559668 chr19:36105986 HAUS5 0.39 6.2 0.32 1.63e-9 Immature fraction of reticulocytes; LIHC cis rs6963495 0.818 rs6944787 chr7:105147309 C/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2635047 0.967 rs12960378 chr18:44614090 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.52 6.48 0.33 3.11e-10 Educational attainment; LIHC cis rs1843834 0.505 rs3820763 chr2:225347270 A/G cg12698349 chr2:225449008 CUL3 -0.66 -10.13 -0.48 2.79e-21 IgE levels in asthmatics (D.p. specific); LIHC cis rs6120849 0.573 rs3746429 chr20:33703607 A/G cg24642439 chr20:33292090 TP53INP2 -0.66 -6.57 -0.33 1.9e-10 Protein C levels; LIHC cis rs2839186 1.000 rs2839186 chr21:47690068 C/T cg12016809 chr21:47604291 C21orf56 0.46 6.69 0.34 9.08e-11 Testicular germ cell tumor; LIHC cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg20090690 chr10:134436459 INPP5A 0.42 5.78 0.3 1.72e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs933688 0.759 rs1423593 chr5:90752351 T/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.84 15.05 0.63 1.27e-39 Smoking behavior; LIHC cis rs6831352 0.879 rs2602879 chr4:100040652 G/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Alcohol dependence; LIHC trans rs2243480 1.000 rs10807702 chr7:65767843 C/T cg10756647 chr7:56101905 PSPH 1.0 12.23 0.55 9.23e-29 Diabetic kidney disease; LIHC cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg07414643 chr4:187882934 NA 0.24 6.14 0.32 2.3e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9902453 0.753 rs3097118 chr17:27978466 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 13.47 0.59 1.85e-33 Coffee consumption (cups per day); LIHC cis rs921968 0.541 rs7603816 chr2:219396255 C/T cg02985541 chr2:219472218 PLCD4 -0.42 -6.83 -0.35 3.99e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2760061 0.598 rs1774755 chr1:228115282 T/G cg02753203 chr1:228287806 NA -0.48 -7.48 -0.37 6.34e-13 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21815882 chr7:26241064 CBX3;HNRNPA2B1 0.44 6.38 0.33 5.62e-10 Pancreatic cancer; LIHC cis rs992157 0.804 rs6758540 chr2:219138625 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.11 -0.55 2.39e-28 Colorectal cancer; LIHC cis rs2153535 0.580 rs7742689 chr6:8452433 C/A cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC cis rs2481665 0.772 rs6668421 chr1:62536619 C/G cg18591186 chr1:62594603 INADL -0.36 -6.07 -0.31 3.46e-9 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9640161 0.742 rs2108852 chr7:150019628 T/C cg21361702 chr7:150065534 REPIN1 0.45 6.17 0.32 1.88e-9 Blood protein levels;Circulating chemerin levels; LIHC trans rs459571 0.959 rs465724 chr9:136910097 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.57 -8.96 -0.44 2.14e-17 Platelet distribution width; LIHC trans rs2243480 1.000 rs13247184 chr7:65358928 A/G cg10756647 chr7:56101905 PSPH 1.11 13.23 0.58 1.43e-32 Diabetic kidney disease; LIHC trans rs4906332 1.000 rs12885762 chr14:103882200 C/A cg17675199 chr6:35436792 RPL10A 0.31 6.08 0.31 3.13e-9 Coronary artery disease; LIHC cis rs2000999 0.778 rs12445401 chr16:72148419 A/G cg16558253 chr16:72132732 DHX38 -0.48 -6.7 -0.34 8.46e-11 Total cholesterol levels;Cholesterol, total;Blood protein levels;LDL cholesterol levels;Haptoglobin levels;LDL cholesterol; LIHC cis rs11764590 0.694 rs60626033 chr7:2099719 A/G cg23422044 chr7:1970798 MAD1L1 -0.55 -8.76 -0.43 9.2e-17 Neuroticism; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg13409248 chr3:40428643 ENTPD3 -0.49 -8.35 -0.41 1.67e-15 Renal cell carcinoma; LIHC cis rs1005277 0.579 rs2474588 chr10:38420870 A/G cg00409905 chr10:38381863 ZNF37A -0.62 -10.86 -0.51 8.71e-24 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.68 0.57 1.91e-30 Alzheimer's disease; LIHC cis rs2180341 0.814 rs6569488 chr6:127726256 C/T cg27446573 chr6:127587934 RNF146 0.8 13.32 0.58 6.62e-33 Breast cancer; LIHC cis rs13108904 0.539 rs13145722 chr4:1338422 T/A cg22903657 chr4:1355424 KIAA1530 -0.39 -5.79 -0.3 1.56e-8 Obesity-related traits; LIHC cis rs1878931 0.668 rs11643983 chr16:3438865 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 22.55 0.77 1.24e-69 Body mass index (adult); LIHC cis rs12960505 0.506 rs7231042 chr18:51024692 A/G cg24270629 chr18:50823537 DCC -0.47 -6.27 -0.32 1.06e-9 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg00750074 chr16:89608354 SPG7 -0.48 -7.59 -0.38 3.09e-13 Multiple myeloma (IgH translocation); LIHC cis rs6089584 0.528 rs881994 chr20:60623931 G/A cg23262073 chr20:60523788 NA -0.28 -5.77 -0.3 1.77e-8 Body mass index; LIHC cis rs13108904 0.870 rs2291199 chr4:1244267 A/G cg13395646 chr4:1353034 KIAA1530 -0.59 -7.93 -0.39 3.06e-14 Obesity-related traits; LIHC cis rs10791097 0.720 rs6590515 chr11:130733365 A/G cg22079354 chr11:130786696 SNX19 -0.4 -5.89 -0.3 9.32e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1707322 1.000 rs7532204 chr1:46485075 C/G cg03146154 chr1:46216737 IPP -0.48 -7.88 -0.39 4.28e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2292096 1.000 rs6660197 chr1:200703541 C/T cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.24 -0.32 1.32e-9 Epilepsy; LIHC cis rs7534824 0.625 rs17448356 chr1:101345093 C/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 7.03 0.36 1.15e-11 Refractive astigmatism; LIHC cis rs10876993 0.890 rs810204 chr12:58075733 T/C cg18357645 chr12:58087776 OS9 0.51 8.46 0.42 7.74e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs4474465 1.000 rs11602360 chr11:78179336 A/G cg27205649 chr11:78285834 NARS2 0.4 6.35 0.32 6.83e-10 Alzheimer's disease (survival time); LIHC trans rs4650994 0.544 rs4652301 chr1:178499799 T/C cg05059571 chr16:84539110 KIAA1609 -0.45 -7.63 -0.38 2.31e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10416265 0.527 rs7508599 chr19:33546512 A/T cg17764715 chr19:33622953 WDR88 0.53 7.13 0.36 6.01e-12 Bone properties (heel); LIHC cis rs7107174 0.901 rs10899473 chr11:78042983 A/C cg02023728 chr11:77925099 USP35 0.47 9.05 0.44 1.07e-17 Testicular germ cell tumor; LIHC cis rs11608355 0.545 rs2302708 chr12:109893726 A/C cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs4065321 0.522 rs3744245 chr17:38146542 C/G cg17467752 chr17:38218738 THRA -0.5 -8.46 -0.42 7.76e-16 White blood cell count (basophil);White blood cell count; LIHC cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs4819052 0.851 rs2330011 chr21:46658498 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.48 6.87 0.35 2.98e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs477895 1.000 rs12785488 chr11:64107521 G/A cg04317338 chr11:64019027 PLCB3 0.84 7.67 0.38 1.77e-13 Mean platelet volume; LIHC cis rs4423214 1.000 rs2276361 chr11:71169648 A/G cg05163923 chr11:71159392 DHCR7 0.87 13.31 0.58 7.31e-33 Vitamin D levels; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg07677032 chr17:61819896 STRADA 0.4 6.02 0.31 4.52e-9 Prudent dietary pattern; LIHC cis rs798554 0.591 rs757791 chr7:2867296 A/G cg19717773 chr7:2847554 GNA12 -0.43 -7.62 -0.38 2.44e-13 Height; LIHC cis rs6952808 0.771 rs10275045 chr7:1920826 C/T cg20295408 chr7:1910781 MAD1L1 -0.51 -7.36 -0.37 1.37e-12 Bipolar disorder and schizophrenia; LIHC cis rs12744310 0.887 rs72667610 chr1:41794810 G/A cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.95e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9596863 0.898 rs13378524 chr13:54372390 G/A ch.13.53330881F chr13:54432880 NA 0.43 5.74 0.3 2.1e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg11764359 chr7:65958608 NA 0.69 9.45 0.46 5.39e-19 Calcium levels; LIHC cis rs7927592 0.645 rs7950900 chr11:68293545 G/A cg16797656 chr11:68205561 LRP5 0.45 7.35 0.37 1.51e-12 Total body bone mineral density; LIHC cis rs6062302 0.522 rs2872810 chr20:62241931 C/T cg16989086 chr20:62203971 PRIC285 -0.56 -8.21 -0.41 4.64e-15 Glioblastoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26035463 chr12:117627651 FBXO21 0.47 6.6 0.34 1.61e-10 Pancreatic cancer; LIHC cis rs2295359 0.892 rs11209004 chr1:67613932 G/A cg12940439 chr1:67600707 NA 0.41 7.27 0.37 2.47e-12 Psoriasis; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs7769051 1.000 rs7769051 chr6:133146796 G/T cg07930552 chr6:133119739 C6orf192 0.69 6.97 0.35 1.62e-11 Type 2 diabetes nephropathy; LIHC cis rs1005277 0.579 rs2474563 chr10:38375938 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg16606324 chr3:10149918 C3orf24 0.54 5.81 0.3 1.4e-8 Alzheimer's disease; LIHC cis rs929354 0.772 rs4716460 chr7:156970054 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.6 8.46 0.42 8.04e-16 Lymphocyte counts; LIHC cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg17644776 chr2:200775616 C2orf69 0.42 6.01 0.31 4.74e-9 Osteoporosis; LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg14828511 chr1:107599125 PRMT6 -0.42 -5.98 -0.31 5.7e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs67460515 0.563 rs13256 chr3:160796505 G/A cg17135325 chr3:160939158 NMD3 0.51 6.89 0.35 2.73e-11 Parkinson's disease; LIHC cis rs66887589 0.837 rs7661498 chr4:120408108 T/C cg09307838 chr4:120376055 NA 0.49 7.59 0.38 3.1400000000000003e-13 Diastolic blood pressure; LIHC cis rs11971779 0.793 rs9632774 chr7:139137562 C/T cg07862535 chr7:139043722 LUC7L2 0.62 9.18 0.44 4.35e-18 Diisocyanate-induced asthma; LIHC cis rs9902453 1.000 rs62070312 chr17:28438877 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.32 0.45 1.43e-18 Coffee consumption (cups per day); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08693231 chr6:34216354 C6orf1 0.46 6.26 0.32 1.15e-9 Lung function (FEV1/FVC); LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg05481257 chr2:20870211 GDF7 -0.42 -8.08 -0.4 1.15e-14 Abdominal aortic aneurysm; LIHC cis rs6500602 0.702 rs4786493 chr16:4500122 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.37 5.74 0.3 2.06e-8 Schizophrenia; LIHC cis rs6430585 0.583 rs11886852 chr2:136589379 G/A cg25344623 chr2:136566232 LCT -0.34 -5.89 -0.3 9.26e-9 Corneal structure; LIHC cis rs8072100 0.875 rs62073966 chr17:45600013 T/A cg19378624 chr17:45501242 LOC100272146;C17orf57 0.36 5.71 0.3 2.39e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10916814 0.632 rs7524492 chr1:20902750 G/A cg24502330 chr1:20914028 CDA -0.31 -6.81 -0.35 4.35e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.63 0.46 1.43e-19 Height; LIHC cis rs11105298 0.891 rs3825330 chr12:89933710 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.44 -0.37 8.12e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg21448741 chr8:58168803 NA 0.36 6.28 0.32 9.99e-10 Developmental language disorder (linguistic errors); LIHC cis rs3008870 0.920 rs3008860 chr1:67391003 G/C cg02640540 chr1:67518911 SLC35D1 0.42 5.78 0.3 1.64e-8 Lymphocyte percentage of white cells; LIHC cis rs12478296 1.000 rs55777943 chr2:243040686 T/C cg05760424 chr2:242988095 NA -0.51 -6.81 -0.35 4.43e-11 Obesity-related traits; LIHC cis rs6459788 0.692 rs10807645 chr7:157258979 T/C cg06271696 chr7:157225062 NA 0.36 6.15 0.32 2.17e-9 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs11628318 0.614 rs7155489 chr14:103123119 C/T cg01864069 chr14:103024347 NA 0.44 6.61 0.34 1.47e-10 Platelet count; LIHC cis rs40363 0.645 rs250631 chr16:3523215 G/C cg21433313 chr16:3507492 NAT15 0.48 8.0 0.4 1.9e-14 Tuberculosis; LIHC cis rs35110281 0.720 rs162394 chr21:44943550 C/G cg21573476 chr21:45109991 RRP1B 0.57 10.65 0.5 4.58e-23 Mean corpuscular volume; LIHC cis rs769267 0.965 rs2074303 chr19:19381755 C/T cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs9733 0.650 rs11204680 chr1:150587140 T/G cg18016565 chr1:150552671 MCL1 -0.54 -11.02 -0.51 2.19e-24 Tonsillectomy; LIHC cis rs8010715 0.848 rs2277483 chr14:24591892 A/G cg23112188 chr14:24563095 PCK2 -0.29 -6.04 -0.31 4.13e-9 IgG glycosylation; LIHC cis rs7843479 1.000 rs11775444 chr8:21813018 A/G cg17168535 chr8:21777572 XPO7 0.41 6.41 0.33 4.77e-10 Mean corpuscular volume; LIHC trans rs6866721 0.791 rs34942052 chr5:116216025 C/A cg07571379 chr11:134631427 NA -0.29 -6.09 -0.31 2.97e-9 Body mass index; LIHC cis rs79057730 0.599 rs4333501 chr7:803244 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.83 9.74 0.47 6.26e-20 Initial pursuit acceleration; LIHC cis rs9814567 0.752 rs4318591 chr3:134328333 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.72 -0.3 2.37e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs561341 0.739 rs7213369 chr17:30211878 G/A cg13647721 chr17:30228624 UTP6 -0.7 -7.8 -0.39 7.58e-14 Hip circumference adjusted for BMI; LIHC trans rs12478296 0.748 rs10185596 chr2:243001029 C/A cg01596870 chr19:55963115 NA -0.58 -7.88 -0.39 4.51e-14 Obesity-related traits; LIHC cis rs2549003 1.000 rs7734334 chr5:131815004 C/A cg21138405 chr5:131827807 IRF1 0.37 9.6 0.46 1.71e-19 Asthma (sex interaction); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26985912 chr7:76179317 LOC100133091 0.45 7.32 0.37 1.82e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10197940 0.550 rs77233070 chr2:152416477 G/A cg06191203 chr2:152266755 RIF1 -0.5 -8.85 -0.43 4.94e-17 Lung cancer; LIHC cis rs1801251 1.000 rs283479 chr2:233648754 A/G cg08000102 chr2:233561755 GIGYF2 0.78 11.75 0.54 5.35e-27 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19643841 chr6:79944399 HMGN3 0.43 6.05 0.31 3.84e-9 Lung function (FEV1/FVC); LIHC cis rs17401966 1.000 rs17401924 chr1:10384439 A/G cg19773385 chr1:10388646 KIF1B -0.48 -8.31 -0.41 2.35e-15 Hepatocellular carcinoma; LIHC cis rs7131987 0.650 rs67146951 chr12:29450553 C/A cg14222432 chr12:29376421 FAR2 0.36 6.97 0.35 1.68e-11 QT interval; LIHC cis rs1577917 0.920 rs1337842 chr6:86675097 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.21 -0.36 3.67e-12 Response to antipsychotic treatment; LIHC cis rs17270561 0.514 rs10946805 chr6:26077891 C/T cg16482183 chr6:26056742 HIST1H1C 0.88 11.5 0.53 4.31e-26 Iron status biomarkers; LIHC cis rs12220238 1.000 rs73284257 chr10:76000710 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.82 0.35 4.26e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs6964587 1.000 rs2888851 chr7:91648341 G/A cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs2033711 0.654 rs734380 chr19:58898963 A/C cg13877915 chr19:58951672 ZNF132 0.38 5.72 0.3 2.3e-8 Uric acid clearance; LIHC cis rs597539 0.652 rs667989 chr11:68685776 T/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.74 9.98 0.47 9.35e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6424115 0.830 rs2503000 chr1:24197898 C/G cg15997130 chr1:24165203 NA 0.38 7.78 0.39 8.76e-14 Immature fraction of reticulocytes; LIHC cis rs7662987 0.517 rs2924580 chr4:100032168 C/G cg12011299 chr4:100065546 ADH4 0.64 10.28 0.49 9.04e-22 Smoking initiation; LIHC cis rs3768617 0.510 rs2296294 chr1:183095596 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs2204008 0.774 rs8186954 chr12:38318566 C/A cg26384229 chr12:38710491 ALG10B 0.57 7.84 0.39 5.81e-14 Bladder cancer; LIHC cis rs2842992 0.789 rs10945635 chr6:160214487 C/A cg11366901 chr6:160182831 ACAT2 0.93 15.43 0.64 3.98e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs9457247 1.000 rs389956 chr6:167407254 T/G cg12798992 chr6:167411361 FGFR1OP 0.6 9.9 0.47 1.8e-20 Crohn's disease; LIHC cis rs539096 0.540 rs3011217 chr1:44303266 C/T cg12908607 chr1:44402522 ARTN 0.44 7.44 0.37 8.43e-13 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs3759893 chr15:45542950 G/T cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC cis rs7584330 0.697 rs9287620 chr2:238368730 C/T cg14458575 chr2:238380390 NA 0.42 6.22 0.32 1.45e-9 Prostate cancer; LIHC cis rs1568889 0.838 rs6484347 chr11:28040969 G/T cg06544937 chr11:28130018 METT5D1;KIF18A -0.66 -13.73 -0.6 1.84e-34 Bipolar disorder; LIHC cis rs2274273 1.000 rs1009977 chr14:55603002 T/G cg04306507 chr14:55594613 LGALS3 0.33 6.19 0.32 1.74e-9 Protein biomarker; LIHC cis rs8031584 0.697 rs8036176 chr15:31175269 A/G cg08109568 chr15:31115862 NA -0.39 -6.15 -0.32 2.21e-9 Huntington's disease progression; LIHC trans rs7677751 0.806 rs890203 chr4:55097405 A/C cg17183009 chr3:120277827 NA 0.52 6.09 0.31 3.02e-9 Corneal astigmatism; LIHC cis rs1570884 0.556 rs2146146 chr13:50170368 C/T cg08779649 chr13:50194554 NA 0.36 6.45 0.33 3.8e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs9378688 1.000 rs9378688 chr6:2235633 G/A cg12303981 chr6:2244766 GMDS -0.49 -6.29 -0.32 9.47e-10 Caudate nucleus volume; LIHC cis rs3824867 0.920 rs4752836 chr11:47465095 T/C cg20307385 chr11:47447363 PSMC3 0.58 7.78 0.39 8.74e-14 Mean corpuscular hemoglobin; LIHC cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg16049864 chr8:95962084 TP53INP1 -0.67 -12.98 -0.57 1.31e-31 Type 2 diabetes; LIHC cis rs10751667 0.643 rs11246344 chr11:933783 A/C ch.11.42038R chr11:967971 AP2A2 0.53 9.58 0.46 2.01e-19 Alzheimer's disease (late onset); LIHC cis rs7264396 0.790 rs6060582 chr20:34313297 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.68 11.85 0.54 2.21e-27 Total cholesterol levels; LIHC cis rs7561273 0.586 rs4149372 chr2:24305512 T/G cg06627628 chr2:24431161 ITSN2 -0.44 -5.83 -0.3 1.26e-8 Quantitative traits; LIHC trans rs7618501 0.815 rs3819325 chr3:49843723 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.77 13.58 0.59 6.74e-34 Intelligence (multi-trait analysis); LIHC cis rs2120019 0.938 rs2289582 chr15:75310394 T/C cg16226627 chr15:75307476 SCAMP5 0.37 7.11 0.36 6.99e-12 Blood trace element (Zn levels); LIHC cis rs4820539 0.902 rs9612237 chr22:23472954 T/C cg14186256 chr22:23484241 RTDR1 0.98 21.08 0.75 8.57e-64 Bone mineral density; LIHC cis rs5769765 1.000 rs5770741 chr22:50270215 A/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs6456156 0.586 rs2001114 chr6:167486578 A/G cg12798992 chr6:167411361 FGFR1OP 0.42 6.37 0.33 6.06e-10 Primary biliary cholangitis; LIHC cis rs10744422 0.925 rs2061098 chr12:123349410 T/C cg07706471 chr12:123319906 HIP1R -0.53 -6.41 -0.33 4.72e-10 Schizophrenia; LIHC cis rs1400745 0.756 rs3783314 chr14:35337384 T/C cg05294307 chr14:35346193 BAZ1A -0.46 -7.76 -0.39 9.72e-14 Monocyte count; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg18767321 chr22:39096505 JOSD1 -0.39 -6.13 -0.31 2.41e-9 Immature fraction of reticulocytes; LIHC cis rs5769765 0.773 rs9616383 chr22:50313014 T/C cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs6138458 1.000 rs227632 chr20:24913729 G/A cg26195577 chr20:24973756 C20orf3 1.14 15.1 0.63 8e-40 Blood protein levels; LIHC trans rs9940464 0.842 rs28549904 chr16:83369972 G/A cg02755603 chr20:18548475 LOC388789 0.34 6.17 0.32 1.94e-9 Malaria; LIHC cis rs1059312 0.966 rs2291349 chr12:129284248 T/C cg09035930 chr12:129282057 SLC15A4 0.68 12.97 0.57 1.41e-31 Systemic lupus erythematosus; LIHC cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg02290350 chr8:58132656 NA 0.45 8.91 0.43 3.17e-17 Developmental language disorder (linguistic errors); LIHC cis rs600806 0.888 rs11102971 chr1:109872370 C/T cg16275483 chr1:110013120 SYPL2 -0.5 -6.22 -0.32 1.44e-9 Intelligence (multi-trait analysis); LIHC cis rs711245 0.573 rs11899523 chr2:36800918 T/C cg01206211 chr2:36825736 FEZ2 0.42 6.75 0.34 6.5e-11 Height; LIHC trans rs5756813 0.705 rs6000886 chr22:38176670 T/C cg19894588 chr14:64061835 NA 0.66 9.58 0.46 2.05e-19 Optic cup area;Vertical cup-disc ratio; LIHC cis rs769267 0.965 rs6511026 chr19:19391402 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC cis rs2204008 0.713 rs11173567 chr12:38089375 T/C cg26384229 chr12:38710491 ALG10B 0.78 9.4 0.45 8.3e-19 Bladder cancer; LIHC cis rs1055129 0.560 rs3682 chr17:73942150 A/G cg19302996 chr17:73780495 UNK -0.48 -6.79 -0.34 4.92e-11 White matter hyperintensity burden; LIHC cis rs10876993 0.855 rs10877007 chr12:58100058 T/A cg18357645 chr12:58087776 OS9 0.51 8.28 0.41 2.77e-15 Celiac disease or Rheumatoid arthritis; LIHC trans rs2288327 0.673 rs6723399 chr2:179381715 G/C cg14011486 chr1:26737247 LIN28 0.54 7.66 0.38 1.92e-13 Atrial fibrillation; LIHC cis rs7572733 0.534 rs7604700 chr2:198718630 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01893041 chr5:67583972 PIK3R1 0.5 7.27 0.37 2.46e-12 Pancreatic cancer; LIHC cis rs9814567 1.000 rs4572812 chr3:134291177 G/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.86 0.3 1.08e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs67311347 0.955 rs6764102 chr3:40378153 C/G cg13409248 chr3:40428643 ENTPD3 0.4 6.42 0.33 4.48e-10 Renal cell carcinoma; LIHC cis rs3540 0.512 rs8033818 chr15:91075535 C/T cg22089800 chr15:90895588 ZNF774 -0.55 -7.67 -0.38 1.8e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2540917 0.654 rs11894442 chr2:60657018 T/C cg00543073 chr2:60773386 BCL11A -0.31 -6.31 -0.32 8.8e-10 Mean corpuscular volume; LIHC cis rs12079745 0.793 rs75487543 chr1:169339382 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 2.01e-11 QT interval; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg00280220 chr17:61926910 NA 0.4 6.23 0.32 1.4e-9 Prudent dietary pattern; LIHC cis rs611744 0.967 rs652485 chr8:109202696 G/A cg18478394 chr8:109455254 TTC35 0.39 6.69 0.34 9.31e-11 Dupuytren's disease; LIHC cis rs2576037 0.583 rs578451 chr18:44404525 T/A cg19077165 chr18:44547161 KATNAL2 -0.47 -6.79 -0.34 4.86e-11 Personality dimensions; LIHC cis rs2153535 0.580 rs7753192 chr6:8482637 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs8060686 0.516 rs8059575 chr16:68272635 C/G cg05110241 chr16:68378359 PRMT7 -0.55 -6.46 -0.33 3.63e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs7909074 0.798 rs10900126 chr10:45386322 G/T cg05187965 chr10:45406764 TMEM72 -0.28 -7.13 -0.36 6.09e-12 Mean corpuscular volume; LIHC cis rs611744 0.967 rs597649 chr8:109187718 T/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg21724239 chr8:58056113 NA 0.49 6.53 0.33 2.43e-10 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.725 rs6947068 chr7:75662056 T/C cg16684958 chr7:75615977 POR -0.51 -8.53 -0.42 4.81e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10818894 1.000 rs10818894 chr9:126695770 A/G cg16191174 chr9:126692580 DENND1A -0.64 -7.36 -0.37 1.37e-12 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15193461 chr17:42977049 CCDC103;EFTUD2 0.44 6.13 0.31 2.38e-9 Lung function (FEV1/FVC); LIHC cis rs1008375 0.902 rs12503164 chr4:17656107 C/T cg02297831 chr4:17616191 MED28 0.5 7.81 0.39 6.97e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2839186 0.732 rs8131458 chr21:47694712 G/A cg09417038 chr21:47716443 C21orf57 -0.56 -8.22 -0.41 4.18e-15 Testicular germ cell tumor; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg16484450 chr15:100350984 NA 0.33 6.7 0.34 8.62e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs34172651 0.876 rs7186893 chr16:24806420 G/T cg00339695 chr16:24857497 SLC5A11 0.55 8.25 0.41 3.44e-15 Intelligence (multi-trait analysis); LIHC trans rs13113518 0.729 rs11133377 chr4:56279875 A/G cg15358633 chr12:38710606 ALG10B 0.44 6.09 0.31 3.07e-9 Height; LIHC cis rs208515 0.525 rs12191500 chr6:66668681 A/G cg07460842 chr6:66804631 NA 0.79 8.92 0.43 2.84e-17 Exhaled nitric oxide levels; LIHC cis rs55665837 0.540 rs10766192 chr11:14811686 A/G cg00085434 chr11:14927489 NA 0.4 5.85 0.3 1.17e-8 Vitamin D levels; LIHC cis rs514406 0.760 rs475969 chr1:53292607 T/A cg24675658 chr1:53192096 ZYG11B -0.66 -10.3 -0.49 7.77e-22 Monocyte count; LIHC cis rs1577917 0.917 rs13196576 chr6:86534066 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.75 -0.3 1.96e-8 Response to antipsychotic treatment; LIHC cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg16145915 chr7:1198662 ZFAND2A -0.33 -7.92 -0.39 3.35e-14 Longevity;Endometriosis; LIHC cis rs2303745 0.589 rs8103523 chr19:17398269 A/G cg04248312 chr19:17393744 ANKLE1 -0.74 -12.15 -0.55 1.74e-28 Systemic lupus erythematosus; LIHC cis rs7772486 0.597 rs6912351 chr6:146264071 T/C cg23711669 chr6:146136114 FBXO30 -0.64 -9.35 -0.45 1.14e-18 Lobe attachment (rater-scored or self-reported); LIHC trans rs800082 0.668 rs9821986 chr3:144292701 T/G cg24215973 chr2:240111563 HDAC4 -0.58 -8.85 -0.43 4.93e-17 Smoking behavior; LIHC cis rs9733 0.596 rs72702504 chr1:150635374 G/C cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs10751667 0.666 rs7395488 chr11:954111 T/C cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.09e-12 Alzheimer's disease (late onset); LIHC cis rs861020 0.710 rs7516902 chr1:210022179 A/G cg09163369 chr1:210001066 C1orf107 0.52 6.65 0.34 1.17e-10 Orofacial clefts; LIHC cis rs116095464 0.558 rs9687621 chr5:229194 C/T cg22857025 chr5:266934 NA -1.56 -16.45 -0.66 3.32e-45 Breast cancer; LIHC cis rs1577917 0.958 rs12215232 chr6:86785430 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.18 -0.48 1.88e-21 Response to antipsychotic treatment; LIHC cis rs2120019 0.638 rs12050628 chr15:75333494 G/A cg09165964 chr15:75287851 SCAMP5 0.76 12.17 0.55 1.47e-28 Blood trace element (Zn levels); LIHC cis rs17102423 0.594 rs942628 chr14:65539463 C/G cg16583315 chr14:65563665 MAX -0.37 -7.61 -0.38 2.74e-13 Obesity-related traits; LIHC trans rs2243480 1.000 rs1796220 chr7:66062100 C/T cg07424592 chr7:64974309 NA 0.77 8.87 0.43 4.13e-17 Diabetic kidney disease; LIHC cis rs7044106 0.791 rs10739572 chr9:123489815 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.75 12.16 0.55 1.68e-28 Hip circumference adjusted for BMI; LIHC cis rs1577917 0.837 rs806529 chr6:86467121 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.5 -0.42 6.14e-16 Response to antipsychotic treatment; LIHC cis rs25645 0.830 rs3935281 chr17:38188419 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.78 15.27 0.64 1.69e-40 Myeloid white cell count; LIHC cis rs548181 0.604 rs11608103 chr11:125627917 G/A cg03464685 chr11:125439445 EI24 -0.77 -8.53 -0.42 4.82e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs116248771 0.739 rs12630515 chr3:158346615 A/G cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.77e-10 diarrhoeal disease at age 2; LIHC cis rs12477438 0.520 rs1133978 chr2:99741964 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg05185784 chr16:90016020 DEF8 -0.45 -5.9 -0.3 8.68e-9 Skin colour saturation; LIHC cis rs611744 0.967 rs677330 chr8:109177572 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs763121 0.853 rs6001175 chr22:39018334 T/C cg06022373 chr22:39101656 GTPBP1 0.74 14.99 0.63 2.08e-39 Menopause (age at onset); LIHC cis rs801193 1.000 rs2659889 chr7:66217112 A/G cg00343986 chr7:65444356 GUSB 0.41 6.16 0.32 2.05e-9 Aortic root size; LIHC cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC cis rs7208859 0.623 rs73269913 chr17:29092183 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.93 0.35 2.06e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7607369 0.580 rs17573724 chr2:219652141 T/A cg02985541 chr2:219472218 PLCD4 -0.37 -5.87 -0.3 1.05e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs757081 0.671 rs214090 chr11:17297161 C/T cg15432903 chr11:17409602 KCNJ11 -0.46 -5.99 -0.31 5.25e-9 Systolic blood pressure; LIHC cis rs8058578 1.000 rs7198250 chr16:30746822 C/A cg02466173 chr16:30829666 NA -0.43 -6.95 -0.35 1.9e-11 Multiple myeloma; LIHC cis rs6088813 0.767 rs4911179 chr20:33972899 A/C cg14752227 chr20:34000481 UQCC -0.41 -5.82 -0.3 1.38e-8 Height; LIHC cis rs4237845 0.804 rs11172372 chr12:58286273 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.44 6.23 0.32 1.38e-9 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.6e-18 Bipolar disorder; LIHC cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg05590025 chr7:65112418 INTS4L2 -0.59 -6.58 -0.34 1.81e-10 Diabetic kidney disease; LIHC cis rs2439831 0.702 rs7171750 chr15:44025858 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.39 0.41 1.33e-15 Lung cancer in ever smokers; LIHC trans rs72960926 0.744 rs72957983 chr6:74968228 A/G cg07247405 chr1:2484626 LOC115110 0.53 6.35 0.32 7e-10 Metabolite levels (MHPG); LIHC cis rs116095464 0.542 rs28650039 chr5:273954 C/A cg22496380 chr5:211416 CCDC127 -1.0 -10.39 -0.49 3.72e-22 Breast cancer; LIHC cis rs1401999 1.000 rs1533684 chr3:183635815 A/G cg05044414 chr3:183734942 ABCC5 0.33 5.73 0.3 2.2e-8 Anterior chamber depth; LIHC cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg09904177 chr6:26538194 HMGN4 0.55 10.59 0.5 7.63e-23 Intelligence (multi-trait analysis); LIHC cis rs151997 0.962 rs27273 chr5:50181074 G/A cg06027927 chr5:50259733 NA 0.57 7.59 0.38 3.09e-13 Callous-unemotional behaviour; LIHC cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.65e-9 Menopause (age at onset); LIHC cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg17691542 chr6:26056736 HIST1H1C 0.39 5.74 0.3 2.08e-8 Height; LIHC cis rs4853012 0.941 rs2421752 chr2:74341615 A/G cg01017244 chr2:74357527 NA 0.63 11.2 0.52 5.34e-25 Gestational age at birth (maternal effect); LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.54e-26 Alzheimer's disease; LIHC cis rs7095944 0.644 rs965484 chr10:126453481 T/C cg08799069 chr10:126477246 METTL10 -0.37 -6.49 -0.33 3.01e-10 Asthma; LIHC cis rs7100689 0.784 rs10736342 chr10:82130005 A/G cg01528321 chr10:82214614 TSPAN14 0.87 11.84 0.54 2.43e-27 Post bronchodilator FEV1; LIHC cis rs769267 0.930 rs4808965 chr19:19631655 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.46 6.22 0.32 1.47e-9 Tonsillectomy; LIHC cis rs882732 1.000 rs10144453 chr14:95045774 T/C cg14866387 chr14:95027382 SERPINA4 -0.48 -6.29 -0.32 9.43e-10 Blood protein levels; LIHC cis rs3008870 1.000 rs3008894 chr1:67377739 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.61 0.67 7.74e-46 Lymphocyte percentage of white cells; LIHC cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.04 -0.31 3.96e-9 Colorectal cancer; LIHC cis rs2295359 0.892 rs17375018 chr1:67655147 A/G cg12940439 chr1:67600707 NA -0.33 -5.81 -0.3 1.44e-8 Psoriasis; LIHC cis rs17854409 0.803 rs1063246 chr20:61472116 G/A cg06598544 chr20:61472147 COL9A3 -0.9 -8.42 -0.41 1.07e-15 Obesity-related traits; LIHC cis rs9916302 0.904 rs12452880 chr17:37591149 G/C cg03013999 chr17:37608204 MED1 0.35 5.74 0.3 2.09e-8 Glomerular filtration rate (creatinine); LIHC cis rs875971 0.660 rs801211 chr7:66015689 T/G cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24111710 chr7:152063974 MLL3 0.42 6.47 0.33 3.33e-10 Longevity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03660134 chr7:149195865 ZNF746 -0.49 -7.13 -0.36 5.91e-12 Lung function (FEV1/FVC); LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC trans rs1814175 0.817 rs10839358 chr11:49770972 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.51 -0.79 2.04e-73 Height; LIHC cis rs17401966 1.000 rs1536263 chr1:10378914 T/C cg15208524 chr1:10270712 KIF1B 0.46 6.72 0.34 7.54e-11 Hepatocellular carcinoma; LIHC cis rs11758351 0.587 rs16891456 chr6:26234127 T/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg11062466 chr8:58055876 NA 0.53 7.13 0.36 6.19e-12 Developmental language disorder (linguistic errors); LIHC cis rs1707322 1.000 rs785490 chr1:46577124 T/C cg03146154 chr1:46216737 IPP -0.46 -7.28 -0.37 2.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12701220 0.553 rs7782024 chr7:1157502 G/T cg16145915 chr7:1198662 ZFAND2A -0.35 -6.95 -0.35 1.9e-11 Bronchopulmonary dysplasia; LIHC trans rs7759633 0.800 rs78199196 chr6:161002749 T/C cg06341590 chr4:57624431 NA -0.59 -6.53 -0.33 2.35e-10 Triglycerides; LIHC cis rs6754311 0.731 rs6719488 chr2:136575199 G/T cg17750252 chr2:136567154 LCT 0.35 6.32 0.32 8.34e-10 Mosquito bite size; LIHC cis rs6088580 0.524 rs6088568 chr20:33265971 A/C cg08999081 chr20:33150536 PIGU -0.43 -7.24 -0.36 2.89e-12 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05477027 chr19:46295590 DMWD 0.42 6.25 0.32 1.21e-9 Pancreatic cancer; LIHC cis rs2197308 0.565 rs12809769 chr12:37909968 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs9394841 0.692 rs56215622 chr6:41892457 G/A cg17623882 chr6:41773611 USP49 -0.43 -5.83 -0.3 1.27e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs67460515 0.563 rs6772723 chr3:160895074 C/G cg03342759 chr3:160939853 NMD3 -0.6 -8.86 -0.43 4.35e-17 Parkinson's disease; LIHC trans rs2710642 0.564 rs6752597 chr2:62823444 T/C cg23713900 chr18:615496 CLUL1 -0.24 -6.14 -0.32 2.28e-9 LDL cholesterol levels;LDL cholesterol; LIHC cis rs12134245 0.776 rs13447526 chr1:91983174 A/G cg07090678 chr1:91966139 CDC7 -0.52 -6.78 -0.34 5.44e-11 Breast cancer; LIHC cis rs2204008 0.837 rs12146734 chr12:38237079 A/G cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC cis rs8180040 0.966 rs11130137 chr3:47578838 C/T cg27129171 chr3:47204927 SETD2 0.53 8.79 0.43 7.56e-17 Colorectal cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03919644 chr3:101443603 CEP97 -0.43 -6.84 -0.35 3.55e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs879568 0.789 rs9959091 chr18:34319676 A/G cg16486109 chr11:613632 IRF7 0.39 6.09 0.31 3.05e-9 QRS duration; LIHC cis rs7772486 0.719 rs7753770 chr6:146066161 G/A cg05347473 chr6:146136440 FBXO30 -0.37 -5.99 -0.31 5.38e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.887 rs4665825 chr2:26333100 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC trans rs1814175 0.619 rs10769623 chr11:49865926 C/T cg15704280 chr7:45808275 SEPT13 -0.95 -19.73 -0.73 2.22e-58 Height; LIHC cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg23758822 chr17:41437982 NA 0.91 16.84 0.67 8.86e-47 Menopause (age at onset); LIHC trans rs2073499 0.935 rs2526393 chr3:50189173 C/G cg21659725 chr3:3221576 CRBN -0.62 -6.66 -0.34 1.11e-10 Schizophrenia; LIHC cis rs1185460 1.000 rs1614264 chr11:118942638 A/C cg23280166 chr11:118938394 VPS11 0.6 8.01 0.4 1.8e-14 Coronary artery disease; LIHC cis rs2991971 0.967 rs512026 chr1:46009946 G/T cg15605315 chr1:45957053 TESK2 0.49 6.62 0.34 1.37e-10 High light scatter reticulocyte count; LIHC cis rs875971 0.928 rs6970357 chr7:65968878 T/C cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.64e-11 Aortic root size; LIHC cis rs929354 0.742 rs7801905 chr7:156940111 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs2574704 1.000 rs2574716 chr3:11662122 A/G cg15876825 chr3:11651881 VGLL4 -0.5 -8.36 -0.41 1.61e-15 Body mass index; LIHC cis rs7772486 0.817 rs2144477 chr6:146406248 C/T cg23711669 chr6:146136114 FBXO30 0.65 11.18 0.52 6.32e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs1555399 0.901 rs12887115 chr14:67990648 C/T cg16224230 chr14:67978224 TMEM229B -0.25 -6.11 -0.31 2.67e-9 Parkinson's disease; LIHC cis rs13088318 0.521 rs7374860 chr3:101223721 A/G cg19452782 chr3:101232218 SENP7 0.41 6.12 0.31 2.5e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7089973 0.646 rs35453961 chr10:116638166 T/C cg23260525 chr10:116636907 FAM160B1 0.37 7.28 0.37 2.31e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7107174 1.000 rs11603112 chr11:78073491 G/A cg02023728 chr11:77925099 USP35 0.41 7.9 0.39 3.83e-14 Testicular germ cell tumor; LIHC cis rs62179067 0.655 rs11890988 chr2:179944932 G/A cg20701897 chr2:179586761 TTN 0.56 5.74 0.3 2.05e-8 Late-onset Alzheimer's disease; LIHC cis rs16854884 0.657 rs16854816 chr3:143734147 A/G cg06585982 chr3:143692056 C3orf58 0.54 7.01 0.35 1.26e-11 Economic and political preferences (feminism/equality); LIHC cis rs6879260 0.714 rs888926 chr5:179738101 A/G cg13944838 chr5:179740914 GFPT2 -0.56 -8.01 -0.4 1.84e-14 Height; LIHC trans rs61931739 0.517 rs34760282 chr12:34153711 G/T cg26384229 chr12:38710491 ALG10B 0.58 7.5 0.38 5.57e-13 Morning vs. evening chronotype; LIHC cis rs11792861 0.926 rs2271878 chr9:111868885 G/A cg13535736 chr9:111863775 C9orf5 -0.38 -5.73 -0.3 2.21e-8 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16853953 chr19:42774803 NA 0.42 6.39 0.33 5.54e-10 Pancreatic cancer; LIHC cis rs4378999 0.623 rs6796642 chr3:51091392 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.38 -5.74 -0.3 2.12e-8 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs1005277 0.579 rs2472183 chr10:38392495 T/G cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.84 -0.3 1.22e-8 Extrinsic epigenetic age acceleration; LIHC cis rs35883536 1.000 rs11586815 chr1:101089079 C/T cg14515779 chr1:101123966 NA -0.67 -13.23 -0.58 1.53e-32 Monocyte count; LIHC cis rs7824557 0.583 rs2736306 chr8:11239762 A/T cg21775007 chr8:11205619 TDH 0.45 5.78 0.3 1.66e-8 Retinal vascular caliber; LIHC cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg11502198 chr6:26597334 ABT1 0.61 9.41 0.45 7.37e-19 Intelligence (multi-trait analysis); LIHC cis rs1023500 0.552 rs5758566 chr22:42454354 G/A cg15557168 chr22:42548783 NA -0.42 -6.54 -0.33 2.28e-10 Schizophrenia; LIHC cis rs3858526 0.727 rs10769353 chr11:5954809 C/T cg05234568 chr11:5960015 NA 0.26 6.34 0.32 7.29e-10 DNA methylation (variation); LIHC cis rs796364 1.000 rs35594306 chr2:200775125 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.69 -6.43 -0.33 4.29e-10 Schizophrenia; LIHC cis rs2404602 0.735 rs437131 chr15:76781051 C/T cg23625390 chr15:77176239 SCAPER 0.49 8.19 0.4 5.37e-15 Blood metabolite levels; LIHC cis rs6963495 0.592 rs114793754 chr7:105152162 G/C cg19920283 chr7:105172520 RINT1 0.67 6.19 0.32 1.73e-9 Bipolar disorder (body mass index interaction); LIHC cis rs950169 0.580 rs17532346 chr15:85171495 A/C cg17507749 chr15:85114479 UBE2QP1 0.67 7.87 0.39 4.66e-14 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg17606287 chr9:99776144 HIATL2 -0.51 -6.35 -0.32 6.67e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2115630 0.967 rs11073731 chr15:85355113 C/A cg12501888 chr15:85177176 SCAND2 -0.49 -7.47 -0.37 6.69e-13 P wave terminal force; LIHC cis rs933688 1.000 rs11959525 chr5:90703840 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.89 16.37 0.66 6.73e-45 Smoking behavior; LIHC cis rs12220238 1.000 rs7904207 chr10:75884474 A/T cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.81 0.35 4.52e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10876993 0.890 rs1082502 chr12:58035706 C/T cg15848620 chr12:58087721 OS9 -0.55 -7.58 -0.38 3.3e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg27170947 chr2:26402098 FAM59B -0.64 -8.25 -0.41 3.56e-15 Gut microbiome composition (summer); LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg06497051 chr1:156261200 TMEM79 0.38 6.05 0.31 3.83e-9 Tonsillectomy; LIHC cis rs11229555 0.645 rs4579945 chr11:58190873 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs11627756 0.958 rs2146430 chr14:103071825 G/T cg12046867 chr14:103022105 NA -0.4 -6.17 -0.32 1.89e-9 Mean platelet volume; LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg24503407 chr1:205819492 PM20D1 0.71 10.1 0.48 3.62e-21 Menarche (age at onset); LIHC cis rs9309473 0.948 rs13391552 chr2:73818936 C/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.63 -0.34 1.27e-10 Metabolite levels; LIHC trans rs10411161 0.657 rs67462252 chr19:52382851 T/C cg22319618 chr22:45562946 NUP50 -0.59 -8.02 -0.4 1.72e-14 Breast cancer; LIHC trans rs7615952 0.673 rs7632557 chr3:125634881 G/C cg07211511 chr3:129823064 LOC729375 -0.85 -10.38 -0.49 3.95e-22 Blood pressure (smoking interaction); LIHC cis rs992157 0.835 rs2271543 chr2:219142491 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.29 -0.55 5.21e-29 Colorectal cancer; LIHC cis rs2235642 0.507 rs2235643 chr16:1585115 A/G cg03034668 chr16:1723424 CRAMP1L 0.4 6.2 0.32 1.62e-9 Coronary artery disease; LIHC trans rs7618501 0.722 rs9853458 chr3:49783211 A/C cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg21248554 chr2:27665150 KRTCAP3 -0.47 -6.36 -0.33 6.39e-10 Total body bone mineral density; LIHC cis rs561341 0.739 rs1978116 chr17:30220978 A/C cg13647721 chr17:30228624 UTP6 0.73 8.13 0.4 7.97e-15 Hip circumference adjusted for BMI; LIHC cis rs10744422 1.000 rs3852536 chr12:123333824 C/T cg18912006 chr12:123335444 HIP1R -0.64 -7.77 -0.39 9.35e-14 Schizophrenia; LIHC cis rs61677309 1.000 rs58520343 chr11:118155000 A/T cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC trans rs1005277 0.579 rs1740749 chr10:38521646 A/G cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs4665809 0.938 rs35844686 chr2:26304949 A/G cg26119090 chr2:26468346 HADHA;HADHB 0.72 7.89 0.39 4.04e-14 Gut microbiome composition (summer); LIHC cis rs4853525 0.522 rs6434412 chr2:191585275 A/G cg10560079 chr2:191398806 TMEM194B -0.41 -5.9 -0.3 8.89e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs652260 0.967 rs667295 chr19:7901634 G/A cg26014689 chr19:7917955 EVI5L -0.67 -11.7 -0.53 8.07e-27 Menarche (age at onset); LIHC cis rs34779708 0.801 rs12098720 chr10:35538683 G/A cg03585969 chr10:35415529 CREM 0.78 11.48 0.53 4.98e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7312933 0.669 rs7974476 chr12:42542484 C/A cg01256987 chr12:42539512 GXYLT1 -0.41 -6.82 -0.35 4.23e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1552244 0.882 rs36006511 chr3:10054191 C/T cg00149659 chr3:10157352 C3orf10 0.54 6.07 0.31 3.45e-9 Alzheimer's disease; LIHC cis rs2180341 0.814 rs9385424 chr6:127726796 A/G cg27446573 chr6:127587934 RNF146 0.8 13.32 0.58 6.62e-33 Breast cancer; LIHC cis rs7223966 1.000 rs55868506 chr17:61851686 T/G cg05941027 chr17:61774174 LIMD2 0.34 7.03 0.36 1.15e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg00091569 chr3:40428383 ENTPD3 0.4 6.77 0.34 5.61e-11 Renal cell carcinoma; LIHC cis rs13191362 1.000 rs35575481 chr6:163007746 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.63 5.74 0.3 2.06e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs253664 0.897 rs1199336 chr3:138088221 T/A cg17918682 chr3:137893718 DBR1 -0.55 -5.77 -0.3 1.76e-8 Body mass index; LIHC cis rs7131987 0.903 rs10843371 chr12:29414232 G/A cg12903224 chr12:29470962 FAR2 -0.42 -6.73 -0.34 7.04e-11 QT interval; LIHC cis rs876084 0.505 rs11985197 chr8:121107553 G/A cg06265175 chr8:121136014 COL14A1 0.48 7.72 0.39 1.34e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs8084351 0.599 rs72923258 chr18:50740767 A/T cg24270629 chr18:50823537 DCC -0.49 -7.16 -0.36 4.88e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2243480 0.708 rs35825036 chr7:65986502 T/C cg05590025 chr7:65112418 INTS4L2 -0.53 -5.75 -0.3 2.01e-8 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg11062466 chr8:58055876 NA 0.5 7.25 0.36 2.81e-12 Developmental language disorder (linguistic errors); LIHC cis rs8017423 0.935 rs7154695 chr14:90795705 C/G cg04374321 chr14:90722782 PSMC1 0.65 11.58 0.53 2.17e-26 Mortality in heart failure; LIHC cis rs1003719 0.788 rs2835605 chr21:38490734 T/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.94 0.54 1.01e-27 Eye color traits; LIHC cis rs7246657 0.943 rs28402338 chr19:37833923 G/A cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC cis rs10791097 0.667 rs4937585 chr11:130741940 A/G cg12179176 chr11:130786555 SNX19 0.81 12.9 0.57 2.65e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1707322 0.835 rs946525 chr1:46487277 A/T cg03146154 chr1:46216737 IPP -0.48 -7.88 -0.39 4.28e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1048238 0.506 rs7552077 chr1:16196759 A/G cg00529422 chr1:16285251 ZBTB17 -0.32 -6.28 -0.32 1e-9 Systolic blood pressure; LIHC cis rs6964587 1.000 rs6969981 chr7:91689461 G/C cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs875971 0.862 rs6955837 chr7:66043142 C/T cg18876405 chr7:65276391 NA -0.34 -6.29 -0.32 9.45e-10 Aortic root size; LIHC cis rs12086130 0.892 rs72906805 chr1:51450445 G/A cg07174182 chr1:51127561 FAF1 -0.92 -9.87 -0.47 2.14e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs709400 0.633 rs10143247 chr14:103920927 G/A cg26031613 chr14:104095156 KLC1 0.72 9.71 0.46 7.42e-20 Body mass index; LIHC cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs875971 0.660 rs1860470 chr7:66103694 G/C cg26939375 chr7:64535504 NA -0.42 -6.8 -0.35 4.54e-11 Aortic root size; LIHC cis rs8067354 0.789 rs1292068 chr17:57929319 T/C cg13753209 chr17:57696993 CLTC 0.55 8.19 0.4 5.38e-15 Hemoglobin concentration; LIHC cis rs4665809 1.000 rs7573118 chr2:26308086 A/G cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.02e-15 Gut microbiome composition (summer); LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg21747090 chr2:27597821 SNX17 -0.44 -6.55 -0.33 2.17e-10 Total body bone mineral density; LIHC cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg06481639 chr22:41940642 POLR3H -0.63 -5.76 -0.3 1.92e-8 Vitiligo; LIHC cis rs11098499 0.954 rs4309825 chr4:120314881 C/T cg09307838 chr4:120376055 NA -0.76 -11.65 -0.53 1.17e-26 Corneal astigmatism; LIHC cis rs4665809 0.590 rs11126339 chr2:26253223 T/C cg27170947 chr2:26402098 FAM59B -0.58 -7.49 -0.38 5.82e-13 Gut microbiome composition (summer); LIHC trans rs3780486 0.718 rs7859454 chr9:33119583 T/A cg04842962 chr6:43655489 MRPS18A 0.87 13.29 0.58 8.6e-33 IgG glycosylation; LIHC cis rs6456156 0.586 rs6456150 chr6:167468922 A/G cg07741184 chr6:167504864 NA 0.3 6.96 0.35 1.79e-11 Primary biliary cholangitis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15985400 chr11:76091674 PRKRIR -0.42 -6.08 -0.31 3.15e-9 Pancreatic cancer; LIHC cis rs9733 0.527 rs11204694 chr1:150653391 G/A cg17724175 chr1:150552817 MCL1 0.49 9.79 0.47 3.97e-20 Tonsillectomy; LIHC cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg20887711 chr4:1340912 KIAA1530 0.49 7.51 0.38 5.16e-13 Obesity-related traits; LIHC cis rs2963155 0.518 rs853178 chr5:142634799 C/T cg17617527 chr5:142782415 NR3C1 0.82 9.14 0.44 5.56e-18 Breast cancer; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg14828511 chr1:107599125 PRMT6 0.4 5.82 0.3 1.35e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4834770 1.000 rs6857641 chr4:120243511 T/C cg09307838 chr4:120376055 NA 0.43 6.5 0.33 2.87e-10 Blood protein levels; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.7 0.62 2.97e-38 Prudent dietary pattern; LIHC cis rs7927592 0.731 rs643609 chr11:68241833 A/G cg20283391 chr11:68216788 NA -0.37 -5.87 -0.3 1.04e-8 Total body bone mineral density; LIHC cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg13047869 chr3:10149882 C3orf24 0.54 6.52 0.33 2.5e-10 Alzheimer's disease; LIHC cis rs1941023 0.584 rs2241920 chr11:60164204 A/G cg08716584 chr11:60157161 MS4A7 0.34 7.76 0.39 9.76e-14 Congenital heart disease (maternal effect); LIHC trans rs6951245 0.554 rs2070118 chr7:1132505 G/A cg13565492 chr6:43139072 SRF -0.89 -7.97 -0.4 2.41e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs875971 0.862 rs778734 chr7:65814849 C/G cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.48e-10 Aortic root size; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19579446 chr11:57335474 UBE2L6 -0.43 -6.2 -0.32 1.58e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3096299 0.606 rs4785573 chr16:89565403 A/G cg06640241 chr16:89574553 SPG7 0.61 8.97 0.44 1.93e-17 Multiple myeloma (IgH translocation); LIHC cis rs1144333 1.000 rs5745327 chr1:76270040 A/T cg22875332 chr1:76189707 ACADM -0.42 -6.88 -0.35 2.84e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs6840360 0.571 rs62327275 chr4:152548238 G/T cg22705602 chr4:152727874 NA -0.34 -6.45 -0.33 3.83e-10 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.501 rs6542868 chr2:99782848 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs27434 0.583 rs26653 chr5:96139250 C/G cg16492584 chr5:96139282 ERAP1 -0.34 -6.38 -0.33 5.61e-10 Ankylosing spondylitis; LIHC cis rs1499614 1.000 rs60326618 chr7:66166358 G/A cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC trans rs11098499 0.865 rs10032158 chr4:120391632 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.77 0.47 4.61e-20 Corneal astigmatism; LIHC cis rs2072499 0.966 rs1060604 chr1:156184268 T/C cg25208724 chr1:156163844 SLC25A44 0.87 13.63 0.59 4.25e-34 Testicular germ cell tumor; LIHC cis rs11718455 0.618 rs35351588 chr3:43926386 C/G cg08738300 chr3:44038990 NA 0.38 6.09 0.31 3.1e-9 Coronary artery disease; LIHC cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.87 -0.3 1.05e-8 Colorectal cancer; LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg12516959 chr21:47718080 NA 0.36 5.96 0.31 6.38e-9 Testicular germ cell tumor; LIHC trans rs4824093 0.610 rs73443974 chr22:50314316 G/A cg09872104 chr7:134855509 C7orf49 -0.76 -6.21 -0.32 1.54e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs7224685 0.569 rs2123841 chr17:4022557 G/C cg09597638 chr17:3907349 NA 0.54 6.68 0.34 9.79e-11 Type 2 diabetes; LIHC cis rs1008375 0.900 rs6851783 chr4:17578469 A/G cg16339924 chr4:17578868 LAP3 0.58 7.5 0.38 5.46e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs694739 0.796 rs479777 chr11:64107477 A/G cg02228329 chr11:64053129 BAD;GPR137 0.66 9.74 0.47 5.99e-20 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7412746 0.658 rs2864869 chr1:150734655 G/A cg18016565 chr1:150552671 MCL1 0.54 10.05 0.48 5.25e-21 Melanoma; LIHC cis rs155076 1.000 rs484365 chr13:21845944 G/T cg11317459 chr13:21872234 NA -1.17 -13.06 -0.58 6.87e-32 White matter hyperintensity burden; LIHC cis rs6430585 0.591 rs77096272 chr2:136663605 C/A cg15123519 chr2:136567270 LCT -0.36 -5.81 -0.3 1.45e-8 Corneal structure; LIHC cis rs904251 0.861 rs1776456 chr6:37484698 C/G cg25019722 chr6:37503610 NA -0.33 -5.75 -0.3 1.95e-8 Cognitive performance; LIHC cis rs2274273 0.837 rs7146748 chr14:55747086 G/A cg01864836 chr14:55583639 NA -0.42 -7.69 -0.38 1.58e-13 Protein biomarker; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg03395511 chr6:291903 DUSP22 0.46 6.22 0.32 1.48e-9 Menopause (age at onset); LIHC cis rs703842 0.963 rs2069506 chr12:58142854 C/A cg04478727 chr12:58166393 METTL1;FAM119B 0.85 13.02 0.58 9.25e-32 Multiple sclerosis; LIHC cis rs11229555 0.645 rs35735990 chr11:58187371 G/A cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs2018683 1.000 rs160837 chr7:29012732 C/G cg19402173 chr7:128379420 CALU -0.43 -6.77 -0.34 5.59e-11 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs3793683 0.858 rs1571145 chr10:134583672 C/G cg26818010 chr10:134567672 INPP5A 0.63 8.46 0.42 7.92e-16 Migraine; LIHC cis rs6754311 0.731 rs2236783 chr2:136594158 G/A cg15123519 chr2:136567270 LCT 0.42 8.7 0.43 1.39e-16 Mosquito bite size; LIHC cis rs1046896 0.553 rs9893885 chr17:80837107 C/T cg22027946 chr17:80790580 TBCD;ZNF750 0.5 7.32 0.37 1.84e-12 Glycated hemoglobin levels; LIHC cis rs2406342 0.528 rs75536638 chr18:74499060 G/T cg14129931 chr18:74513950 NA 0.45 5.87 0.3 1.01e-8 Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin); LIHC cis rs1997103 1.000 rs12718956 chr7:55407763 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9486715 0.867 rs4240553 chr6:96965324 T/C cg06623918 chr6:96969491 KIAA0776 0.86 15.04 0.63 1.41e-39 Headache; LIHC cis rs1865760 0.964 rs6932113 chr6:25913098 C/T cg17691542 chr6:26056736 HIST1H1C 0.39 5.91 0.3 8.44e-9 Height; LIHC cis rs963731 0.649 rs297151 chr2:39326511 A/C cg04010122 chr2:39346883 SOS1 -0.61 -6.1 -0.31 2.83e-9 Corticobasal degeneration; LIHC cis rs2836974 0.604 rs2854727 chr21:40713787 A/G cg11890956 chr21:40555474 PSMG1 0.61 9.25 0.45 2.58e-18 Cognitive function; LIHC cis rs11608355 0.515 rs7955932 chr12:109941303 G/A cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs116248771 0.739 rs6801874 chr3:158347396 C/G cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.75e-10 diarrhoeal disease at age 2; LIHC cis rs8058578 1.000 rs8058578 chr16:30726248 C/T cg02466173 chr16:30829666 NA -0.46 -7.3 -0.37 2.04e-12 Multiple myeloma; LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg22963979 chr7:1858916 MAD1L1 -0.44 -7.18 -0.36 4.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs2290405 0.527 rs7663192 chr4:923947 T/C cg04824913 chr4:887549 GAK 0.55 8.58 0.42 3.34e-16 Systemic sclerosis; LIHC cis rs6089829 0.962 rs6089824 chr20:61659207 A/G cg08564027 chr20:61660810 NA 0.4 7.71 0.38 1.38e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs35110281 0.511 rs2298562 chr21:45085236 A/G cg04455712 chr21:45112962 RRP1B 0.54 9.24 0.45 2.69e-18 Mean corpuscular volume; LIHC cis rs11105298 0.891 rs10858899 chr12:89923811 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.3 -0.37 2.09e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs265548 0.608 rs36690 chr19:17910483 C/T cg04517722 chr19:17905589 B3GNT3 0.44 6.75 0.34 6.25e-11 Tumor biomarkers; LIHC cis rs1982963 0.901 rs2516589 chr14:52512610 A/G cg10843707 chr14:52510701 NID2 -0.47 -8.46 -0.42 7.86e-16 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2274273 0.682 rs7141975 chr14:55542216 G/C cg01864836 chr14:55583639 NA -0.4 -6.44 -0.33 3.98e-10 Protein biomarker; LIHC cis rs929354 0.772 rs6967764 chr7:156994964 C/T cg16102536 chr7:156981717 UBE3C 0.35 5.92 0.3 7.91e-9 Body mass index; LIHC cis rs854765 0.583 rs2350977 chr17:17802779 A/G cg04398451 chr17:18023971 MYO15A -0.43 -5.94 -0.31 7.18e-9 Total body bone mineral density; LIHC cis rs7927592 0.913 rs4988291 chr11:68381607 G/A cg16797656 chr11:68205561 LRP5 0.49 7.71 0.38 1.39e-13 Total body bone mineral density; LIHC cis rs13191362 1.000 rs35723993 chr6:163008197 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4975709 0.569 rs4975743 chr5:1859941 G/T cg14773178 chr5:1868261 NA 0.27 7.05 0.36 1.01e-11 Cardiovascular disease risk factors; LIHC cis rs7619427 0.643 rs6791785 chr3:44093101 G/A cg24966902 chr3:44043705 NA 0.54 6.9 0.35 2.49e-11 Schizophrenia; LIHC cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg23262073 chr20:60523788 NA -0.3 -6.29 -0.32 9.89e-10 Body mass index; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg11060661 chr22:24314208 DDT;DDTL 0.68 12.09 0.55 2.83e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2073300 1.000 rs12625999 chr20:23442085 A/G cg12062639 chr20:23401060 NAPB -0.87 -10.39 -0.49 3.62e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.11 0.55 2.44e-28 Height; LIHC cis rs7296418 0.518 rs28825193 chr12:123878262 T/C cg05973401 chr12:123451056 ABCB9 0.42 6.35 0.32 6.75e-10 Platelet count; LIHC trans rs208520 0.754 rs1100989 chr6:66880532 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.61 -0.42 2.75e-16 Exhaled nitric oxide output; LIHC cis rs3820068 0.705 rs74054769 chr1:15860147 A/C cg17385448 chr1:15911702 AGMAT 0.38 6.38 0.33 5.66e-10 Systolic blood pressure; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg08219700 chr8:58056026 NA 0.52 7.15 0.36 5.22e-12 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.575 rs6950330 chr7:1953606 T/C cg14004847 chr7:1930337 MAD1L1 -0.55 -8.2 -0.41 4.9e-15 Bipolar disorder and schizophrenia; LIHC cis rs7707921 0.602 rs10514231 chr5:81307412 C/T cg15871215 chr5:81402204 ATG10 0.72 9.59 0.46 1.88e-19 Breast cancer; LIHC trans rs9914544 1.000 rs9914544 chr17:18787828 A/C cg04702396 chr17:15466718 FAM18B2 0.43 6.47 0.33 3.3e-10 Educational attainment (years of education); LIHC cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg12292205 chr6:26970375 C6orf41 0.37 6.33 0.32 7.92e-10 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs7636817 chr3:10014876 G/T cg00149659 chr3:10157352 C3orf10 0.49 5.73 0.3 2.25e-8 Alzheimer's disease; LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg14828511 chr1:107599125 PRMT6 -0.42 -6.01 -0.31 4.79e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4808199 0.948 rs2301668 chr19:19452249 G/A cg03709012 chr19:19516395 GATAD2A 0.99 15.84 0.65 9.42e-43 Nonalcoholic fatty liver disease; LIHC cis rs7312933 0.584 rs7974654 chr12:42630466 C/A cg01256987 chr12:42539512 GXYLT1 -0.42 -7.0 -0.35 1.32e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6831352 0.918 rs29001232 chr4:100046654 G/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg11965913 chr1:205819406 PM20D1 0.62 9.06 0.44 1.05e-17 Menarche (age at onset); LIHC trans rs6542647 0.541 rs113341692 chr2:4971943 T/G cg16523137 chr18:5237527 LOC339290;C18orf18 0.61 6.11 0.31 2.69e-9 Left ventricular obstructive tract defect (inherited effect); LIHC cis rs6500602 0.727 rs55939215 chr16:4541390 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.49 0.38 6e-13 Schizophrenia; LIHC cis rs2832191 0.633 rs2832166 chr21:30462395 G/C cg24692254 chr21:30365293 RNF160 0.88 15.59 0.64 9.16e-42 Dental caries; LIHC cis rs1499280 0.920 rs975886 chr5:52101227 T/C cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs921968 0.509 rs655441 chr2:219357545 C/T cg02985541 chr2:219472218 PLCD4 0.43 6.95 0.35 1.84e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.931 rs7810038 chr7:1894116 T/C cg21782813 chr7:2030301 MAD1L1 0.4 6.58 0.34 1.75e-10 Bipolar disorder and schizophrenia; LIHC cis rs4755351 0.553 rs11032158 chr11:33161290 G/A cg05567920 chr11:33183001 CSTF3 0.43 6.23 0.32 1.33e-9 Lung cancer in ever smokers; LIHC cis rs10857712 0.551 rs12252576 chr10:135227244 T/C cg01444801 chr10:135216882 MTG1 -0.55 -8.92 -0.43 2.86e-17 Systemic lupus erythematosus; LIHC cis rs6138458 0.961 rs11700073 chr20:24975215 C/G cg26195577 chr20:24973756 C20orf3 1.2 16.23 0.66 2.61e-44 Blood protein levels; LIHC cis rs7224685 0.530 rs7221574 chr17:4007543 T/C cg09597638 chr17:3907349 NA 0.52 6.42 0.33 4.44e-10 Type 2 diabetes; LIHC cis rs7914558 0.899 rs7913682 chr10:104684392 T/A cg15744005 chr10:104629667 AS3MT -0.4 -9.05 -0.44 1.1e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs57221529 0.766 rs72703070 chr5:590458 T/C cg09021430 chr5:549028 NA -0.43 -8.53 -0.42 4.8e-16 Lung disease severity in cystic fibrosis; LIHC cis rs9790314 0.902 rs9863590 chr3:161116445 T/C cg04691961 chr3:161091175 C3orf57 -0.39 -6.1 -0.31 2.88e-9 Morning vs. evening chronotype; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg22997768 chr12:11092816 TAS2R14;PRR4;PRH1 0.36 6.46 0.33 3.61e-10 Hepatitis; LIHC cis rs7772486 0.764 rs2265468 chr6:146218346 A/C cg05347473 chr6:146136440 FBXO30 0.37 5.77 0.3 1.77e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.620 rs3737194 chr10:99130127 A/G cg06359132 chr10:99160096 RRP12 -0.36 -5.72 -0.3 2.28e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs9814567 1.000 rs6769885 chr3:134286913 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9517320 0.515 rs1107379 chr13:99198921 C/T cg07423050 chr13:99094983 FARP1 -0.51 -8.95 -0.44 2.36e-17 Longevity; LIHC cis rs1127311 0.901 rs11264223 chr1:154565519 G/A cg17218026 chr1:154582156 ADAR 0.36 6.99 0.35 1.41e-11 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC trans rs6489882 0.867 rs4767036 chr12:113369177 T/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg11062466 chr8:58055876 NA 0.39 5.73 0.3 2.2e-8 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg18538332 chr22:24372958 LOC391322 -0.55 -7.94 -0.39 2.97e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs35146811 0.586 rs1076237 chr7:99585441 A/C cg19636519 chr7:99541626 NA 0.3 5.72 0.3 2.37e-8 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02287918 chr21:30396957 USP16 -0.47 -6.43 -0.33 4.27e-10 Pancreatic cancer; LIHC cis rs4919694 1.000 rs12245779 chr10:104645944 C/A cg04362960 chr10:104952993 NT5C2 1.12 8.76 0.43 9.54e-17 Arsenic metabolism; LIHC cis rs2839186 0.814 rs12482209 chr21:47664275 C/G cg12379764 chr21:47803548 PCNT 0.58 8.44 0.42 8.99e-16 Testicular germ cell tumor; LIHC cis rs12479064 0.724 rs2309618 chr2:99974473 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -7.78 -0.39 8.81e-14 Chronic sinus infection; LIHC trans rs208520 1.000 rs12191598 chr6:66983962 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.09 0.36 7.85e-12 Exhaled nitric oxide output; LIHC cis rs1403694 0.515 rs1648699 chr3:186449890 G/C cg12454167 chr3:186435060 KNG1 0.29 7.01 0.35 1.28e-11 Blood protein levels; LIHC trans rs11098499 0.863 rs3775841 chr4:120425777 A/C cg25214090 chr10:38739885 LOC399744 0.59 9.42 0.45 6.93e-19 Corneal astigmatism; LIHC cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg27286337 chr10:134555280 INPP5A 0.89 13.18 0.58 2.27e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7577696 0.512 rs9789593 chr2:32381110 T/G cg02381751 chr2:32503542 YIPF4 -0.44 -5.95 -0.31 6.75e-9 Inflammatory biomarkers; LIHC cis rs7312933 1.000 rs12372623 chr12:42531666 G/A cg01256987 chr12:42539512 GXYLT1 -0.42 -7.15 -0.36 5.41e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs2243480 1.000 rs35432774 chr7:65393019 G/C cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.71 -0.57 1.46e-30 Alzheimer's disease; LIHC cis rs9628987 0.500 rs55823627 chr1:8462079 C/T cg20416874 chr1:8611966 RERE 0.5 5.9 0.3 8.61e-9 Breast cancer; LIHC cis rs62380364 0.602 rs448809 chr5:88005828 G/T cg22951263 chr5:87985283 NA -0.38 -6.71 -0.34 8.03e-11 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg07133347 chr1:107600762 PRMT6 0.42 6.2 0.32 1.62e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg05255149 chr17:80675120 FN3KRP -0.44 -6.41 -0.33 4.7e-10 Glycated hemoglobin levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06791812 chr14:105677543 BRF1 0.41 6.05 0.31 3.74e-9 Longevity; LIHC cis rs7208859 0.573 rs73267865 chr17:29064204 C/G cg13385521 chr17:29058706 SUZ12P 0.82 8.18 0.4 5.51e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1707322 0.785 rs10890348 chr1:46242423 G/T cg03146154 chr1:46216737 IPP 0.51 8.32 0.41 2.17e-15 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6912958 0.781 rs6916732 chr6:88259225 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.01 -0.4 1.84e-14 Monocyte percentage of white cells; LIHC cis rs17102423 0.594 rs1271582 chr14:65564703 T/G cg16583315 chr14:65563665 MAX -0.38 -7.85 -0.39 5.55e-14 Obesity-related traits; LIHC cis rs4423214 1.000 rs909217 chr11:71146577 G/A cg05163923 chr11:71159392 DHCR7 0.91 13.86 0.6 5.73e-35 Vitamin D levels; LIHC cis rs941873 0.772 rs1316312 chr10:81110417 G/C cg11057378 chr10:81107060 PPIF 0.36 5.76 0.3 1.89e-8 Height; LIHC cis rs4700695 0.925 rs1845481 chr5:65397527 A/C cg21114390 chr5:65439923 SFRS12 -0.5 -6.92 -0.35 2.24e-11 Facial morphology (factor 19); LIHC trans rs1814175 0.564 rs12416819 chr11:49755567 T/C cg15704280 chr7:45808275 SEPT13 -0.97 -20.37 -0.74 5.91e-61 Height; LIHC cis rs2645694 0.626 rs12502590 chr4:77823642 G/A cg03477792 chr4:77819574 ANKRD56 0.58 8.4 0.41 1.24e-15 Emphysema distribution in smoking; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 24.32 0.8 1.44e-76 Prudent dietary pattern; LIHC cis rs2236918 0.687 rs1776136 chr1:242026845 G/A cg17736920 chr1:242011382 EXO1 0.42 6.28 0.32 1.03e-9 Menopause (age at onset); LIHC cis rs12477438 0.765 rs62154861 chr2:99590235 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.79 -10.4 -0.49 3.54e-22 Chronic sinus infection; LIHC cis rs8017423 1.000 rs2183189 chr14:90670057 A/G cg14092571 chr14:90743983 NA -0.36 -5.74 -0.3 2.14e-8 Mortality in heart failure; LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg02993280 chr1:107599747 PRMT6 0.61 9.79 0.47 4.04e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6963495 0.818 rs73190200 chr7:105165856 T/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs67340775 0.541 rs200964 chr6:27866943 G/C cg23485639 chr6:28045615 ZNF165 0.51 5.77 0.3 1.78e-8 Lung cancer in ever smokers; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg12720424 chr1:94713229 NA 0.43 6.22 0.32 1.48e-9 Hepatitis; LIHC trans rs7613875 0.580 rs12634780 chr3:50043341 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.42 -6.39 -0.33 5.58e-10 Body mass index; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC cis rs7666738 0.830 rs10034619 chr4:98970067 G/C cg05340658 chr4:99064831 C4orf37 0.71 13.13 0.58 3.47e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs11122272 0.735 rs2749714 chr1:231538634 G/C cg06096015 chr1:231504339 EGLN1 0.49 9.08 0.44 8.78e-18 Hemoglobin concentration; LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs6088580 0.634 rs6088502 chr20:33037644 A/T cg08999081 chr20:33150536 PIGU 0.67 13.36 0.59 4.63e-33 Glomerular filtration rate (creatinine); LIHC cis rs6009527 0.752 rs7288176 chr22:49568462 A/G cg12746016 chr22:49560550 NA -0.26 -6.11 -0.31 2.67e-9 Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07897448 chr8:95907691 CCNE2 0.42 6.66 0.34 1.08e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9868809 0.772 rs9812200 chr3:48695667 A/G cg07636037 chr3:49044803 WDR6 0.61 7.41 0.37 9.73e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs35110281 0.782 rs9981291 chr21:45031458 A/G cg04455712 chr21:45112962 RRP1B 0.47 7.85 0.39 5.34e-14 Mean corpuscular volume; LIHC cis rs1577917 0.771 rs2842607 chr6:86345039 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.96 -0.4 2.51e-14 Response to antipsychotic treatment; LIHC cis rs875971 0.895 rs3857684 chr7:65938158 G/C cg18876405 chr7:65276391 NA 0.37 6.66 0.34 1.08e-10 Aortic root size; LIHC cis rs2404602 1.000 rs2120107 chr15:76869789 A/G cg23625390 chr15:77176239 SCAPER 0.37 6.24 0.32 1.3e-9 Blood metabolite levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg11997514 chr19:40562314 ZNF780B 0.33 6.34 0.32 7.21e-10 Calcium levels; LIHC cis rs4820294 1.000 rs62236665 chr22:38059847 C/A cg10587741 chr22:38071170 LGALS1 0.72 12.65 0.56 2.46e-30 Fat distribution (HIV); LIHC cis rs2070488 1.000 rs13089394 chr3:38446309 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.63 0.65 6.13e-42 Electrocardiographic conduction measures; LIHC cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.68 -0.38 1.73e-13 Electroencephalogram traits; LIHC cis rs7727544 0.735 rs2631370 chr5:131703776 T/C cg07395648 chr5:131743802 NA 0.32 6.64 0.34 1.25e-10 Blood metabolite levels; LIHC cis rs1580019 0.587 rs34488151 chr7:32548146 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.12 0.31 2.56e-9 Cognitive ability; LIHC cis rs11711311 0.955 rs7650764 chr3:113414439 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.39 7.41 0.37 1.02e-12 IgG glycosylation; LIHC cis rs2230307 0.536 rs2893426 chr1:100528200 G/T cg24955406 chr1:100503596 HIAT1 0.62 6.16 0.32 2e-9 Carotid intima media thickness; LIHC cis rs3008870 1.000 rs2755248 chr1:67492624 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.35 0.66 8.35e-45 Lymphocyte percentage of white cells; LIHC cis rs11105298 0.786 rs10858897 chr12:89922032 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.3 -0.37 2.09e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7927771 0.507 rs11039432 chr11:47873327 G/A cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.29e-24 Subjective well-being; LIHC cis rs172166 0.637 rs1225592 chr6:28150242 G/A cg23485639 chr6:28045615 ZNF165 0.38 6.04 0.31 4.02e-9 Cardiac Troponin-T levels; LIHC cis rs6912958 0.525 rs586771 chr6:88064971 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.39 7.7 0.38 1.5e-13 Monocyte percentage of white cells; LIHC cis rs7223966 1.000 rs8080211 chr17:61729882 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 6.82 0.35 4.23e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs910316 0.967 rs2268619 chr14:75640354 C/G cg11812906 chr14:75593930 NEK9 -0.77 -14.51 -0.62 1.72e-37 Height; LIHC cis rs8180040 0.903 rs11130124 chr3:47292183 T/C cg16586182 chr3:47516702 SCAP -0.54 -9.77 -0.47 4.62e-20 Colorectal cancer; LIHC cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg06481639 chr22:41940642 POLR3H -0.61 -5.78 -0.3 1.65e-8 Vitiligo; LIHC cis rs12960505 0.506 rs9948611 chr18:50975873 T/C cg24270629 chr18:50823537 DCC -0.47 -6.52 -0.33 2.57e-10 Intelligence (multi-trait analysis); LIHC cis rs4988958 0.565 rs1035125 chr2:103033839 C/A cg03938978 chr2:103052716 IL18RAP 0.3 5.72 0.3 2.31e-8 Asthma (childhood onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22779765 chr14:103369786 TRAF3 -0.43 -6.16 -0.32 2.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg11062466 chr8:58055876 NA 0.5 6.9 0.35 2.56e-11 Developmental language disorder (linguistic errors); LIHC cis rs8078723 0.933 rs55846942 chr17:38164470 G/A cg17467752 chr17:38218738 THRA 0.76 13.99 0.6 1.82e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg03396347 chr1:1875803 NA -0.48 -8.79 -0.43 7.42e-17 Body mass index; LIHC cis rs7192750 0.586 rs12935795 chr16:71987452 G/C cg06353428 chr16:71660113 MARVELD3 0.77 8.83 0.43 5.47e-17 LDL cholesterol levels;Total cholesterol levels; LIHC trans rs6600671 0.934 rs11249348 chr1:121188302 T/C cg09829573 chr1:144692074 NBPF9 -0.43 -7.81 -0.39 7.05e-14 Hip geometry; LIHC cis rs2836950 0.501 rs2836983 chr21:40689336 G/A cg06238570 chr21:40685208 BRWD1 -0.45 -7.42 -0.37 9.54e-13 Menarche (age at onset); LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg23218760 chr8:16884364 EFHA2 -0.51 -6.36 -0.33 6.58e-10 Monocyte count; LIHC cis rs2842992 0.714 rs2495278 chr6:160123674 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.56 9.69 0.46 9.08e-20 Age-related macular degeneration (geographic atrophy); LIHC cis rs9929218 0.954 rs112225541 chr16:68755165 C/T cg01231543 chr16:68741748 NA 0.39 6.13 0.31 2.41e-9 Colorectal cancer; LIHC trans rs35110281 0.743 rs2329443 chr21:45059431 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.07 0.31 3.36e-9 Mean corpuscular volume; LIHC cis rs10197940 0.662 rs6735771 chr2:152273503 G/A cg19508488 chr2:152266495 RIF1 -0.58 -8.32 -0.41 2.13e-15 Lung cancer; LIHC cis rs10489202 0.535 rs12736786 chr1:167988283 C/G cg24449463 chr1:168025552 DCAF6 -0.58 -8.75 -0.43 9.86e-17 Schizophrenia; LIHC cis rs713477 1.000 rs12888361 chr14:55906187 A/G cg13175173 chr14:55914753 NA -0.35 -8.13 -0.4 7.98e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs4242434 0.819 rs6558173 chr8:22492103 A/C cg03733263 chr8:22462867 KIAA1967 -0.74 -13.96 -0.6 2.33e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs477895 0.713 rs67546972 chr11:63962162 G/A cg18225595 chr11:63971243 STIP1 0.68 8.42 0.41 1.04e-15 Mean platelet volume; LIHC cis rs11233413 0.874 rs3793986 chr11:82704967 C/A cg24227371 chr11:82718527 RAB30 -0.32 -6.91 -0.35 2.34e-11 Economic and political preferences (feminism/equality); LIHC cis rs1059312 0.808 rs10847693 chr12:129292006 G/A cg09035930 chr12:129282057 SLC15A4 0.6 11.23 0.52 4.14e-25 Systemic lupus erythematosus; LIHC cis rs7914558 0.646 rs10883795 chr10:104654577 T/C cg15744005 chr10:104629667 AS3MT -0.35 -7.38 -0.37 1.22e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7223966 1.000 rs9891018 chr17:61827856 A/G cg05941027 chr17:61774174 LIMD2 0.35 7.34 0.37 1.53e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1348850 0.958 rs4893965 chr2:178463852 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.29 0.52 2.45e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg08280861 chr8:58055591 NA 0.48 5.81 0.3 1.43e-8 Developmental language disorder (linguistic errors); LIHC cis rs826838 0.651 rs1843892 chr12:38616965 A/G cg26384229 chr12:38710491 ALG10B 0.45 7.06 0.36 9.05e-12 Heart rate; LIHC cis rs600806 0.778 rs2043059 chr1:109991009 C/A cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.32 -0.32 8.08e-10 Intelligence (multi-trait analysis); LIHC cis rs1843834 0.716 rs6716600 chr2:225481991 A/T cg22509189 chr2:225307070 NA -0.56 -7.09 -0.36 7.58e-12 IgE levels in asthmatics (D.p. specific); LIHC cis rs1691799 0.899 rs1168317 chr12:66746225 C/T cg16791601 chr12:66731901 HELB -0.56 -13.81 -0.6 8.57e-35 White blood cell count (basophil); LIHC cis rs9733 0.744 rs12568757 chr1:150729793 C/T cg17724175 chr1:150552817 MCL1 -0.38 -7.52 -0.38 4.77e-13 Tonsillectomy; LIHC cis rs7927771 0.524 rs4752798 chr11:47886364 T/C cg20307385 chr11:47447363 PSMC3 -0.65 -9.77 -0.47 4.92e-20 Subjective well-being; LIHC cis rs13161895 0.941 rs438050 chr5:179414645 T/C cg06664874 chr5:179499304 RNF130 0.57 7.02 0.35 1.21e-11 LDL cholesterol; LIHC cis rs7100689 0.784 rs4934083 chr10:82116501 G/C cg00277334 chr10:82204260 NA -0.54 -6.57 -0.33 1.87e-10 Post bronchodilator FEV1; LIHC cis rs12597458 0.763 rs3213422 chr16:72042682 A/C cg01557791 chr16:72042693 DHODH 0.73 13.25 0.58 1.21e-32 Prostate cancer; LIHC cis rs10540 0.558 rs12806062 chr11:501429 G/A cg03576123 chr11:487126 PTDSS2 -1.3 -9.49 -0.46 4.2e-19 Body mass index; LIHC cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg11890956 chr21:40555474 PSMG1 1.04 14.86 0.63 6.67e-39 Cognitive function; LIHC cis rs644799 0.542 rs10831416 chr11:95467220 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.53 6.77 0.34 5.58e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs589448 0.934 rs554591 chr12:69753847 T/C cg19645103 chr12:69753606 YEATS4 -0.4 -5.92 -0.3 7.74e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg03354898 chr7:1950403 MAD1L1 -0.37 -5.75 -0.3 1.98e-8 Bipolar disorder and schizophrenia; LIHC cis rs9303401 0.573 rs34717648 chr17:56886624 T/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.86 0.43 4.6e-17 Cognitive test performance; LIHC cis rs7927771 1.000 rs9909 chr11:47799775 C/G cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.38e-18 Subjective well-being; LIHC cis rs13108904 0.517 rs7671242 chr4:1339875 G/A cg00684032 chr4:1343700 KIAA1530 0.56 7.86 0.39 5.04e-14 Obesity-related traits; LIHC cis rs6733011 0.622 rs12712036 chr2:99462711 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.42 -5.74 -0.3 2.08e-8 Bipolar disorder; LIHC cis rs9467773 1.000 rs10484442 chr6:26555879 A/G cg11502198 chr6:26597334 ABT1 0.46 6.69 0.34 9.06e-11 Intelligence (multi-trait analysis); LIHC cis rs7223966 1.000 rs7214312 chr17:61870863 A/G cg05941027 chr17:61774174 LIMD2 0.35 7.35 0.37 1.48e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg04234412 chr22:24373322 LOC391322 0.66 9.47 0.46 4.81e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs7618501 0.933 rs1128535 chr3:49866392 C/T cg21582582 chr3:182698605 DCUN1D1 0.54 7.13 0.36 6.18e-12 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs2255766 chr21:46683777 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.74 0.39 1.17e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6933660 0.745 rs3800272 chr6:151744283 A/G cg14416726 chr6:151773293 C6orf211;RMND1 0.54 8.38 0.41 1.35e-15 Menarche (age at onset); LIHC cis rs5850 0.602 rs1005786 chr7:23145837 G/C cg23682824 chr7:23144976 KLHL7 0.4 5.98 0.31 5.7e-9 Blood protein levels; LIHC trans rs1075232 0.655 rs80220087 chr15:31555817 G/A cg04373760 chr16:53404718 NA 0.68 6.63 0.34 1.27e-10 Survival in colorectal cancer (non-distant metastatic); LIHC trans rs2727020 0.615 rs35423199 chr11:49514914 T/C cg18944383 chr4:111397179 ENPEP 0.25 6.32 0.32 8.09e-10 Coronary artery disease; LIHC cis rs6811802 1 rs6811802 chr4:78932838 G/C cg07207937 chr4:78783799 MRPL1 -0.8 -12.04 -0.55 4.57e-28 Left ventricular obstructive tract defect (inherited effect); LIHC cis rs35883536 0.967 rs4991930 chr1:101122755 T/C cg14515779 chr1:101123966 NA -0.69 -13.75 -0.6 1.45e-34 Monocyte count; LIHC cis rs11031096 0.678 rs2044135 chr11:4187233 G/A cg18678763 chr11:4115507 RRM1 -0.42 -6.08 -0.31 3.25e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs36051895 0.623 rs2146040 chr9:5260039 C/G cg02405213 chr9:5042618 JAK2 0.62 10.42 0.49 3.01e-22 Pediatric autoimmune diseases; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg15674719 chr19:1407747 DAZAP1 -0.39 -6.29 -0.32 9.95e-10 Neuroblastoma; LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg00106254 chr7:1943704 MAD1L1 -0.48 -8.01 -0.4 1.84e-14 Bipolar disorder and schizophrenia; LIHC cis rs2439831 1.000 rs2444032 chr15:43755346 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.54 0.59 9.26e-34 Lung cancer in ever smokers; LIHC cis rs1865721 0.771 rs6566092 chr18:73136496 C/T cg26385618 chr18:73139727 C18orf62 -0.32 -8.71 -0.43 1.35e-16 Intelligence; LIHC cis rs921968 0.643 rs2243911 chr2:219529348 C/T cg17980119 chr2:219472607 PLCD4 -0.34 -5.75 -0.3 2e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs10170846 0.861 rs12694582 chr2:223521955 G/C cg25565276 chr2:223520875 FARSB 0.63 9.32 0.45 1.52e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs6973256 0.605 rs6467499 chr7:133348922 G/T cg10665199 chr7:133106180 EXOC4 -0.34 -5.82 -0.3 1.32e-8 Intelligence (multi-trait analysis); LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.41 8.77 0.43 8.42e-17 Calcium levels; LIHC trans rs911555 0.755 rs1116095 chr14:103931879 A/G cg17675199 chr6:35436792 RPL10A -0.44 -9.2 -0.45 3.51e-18 Intelligence (multi-trait analysis); LIHC cis rs11055008 0.620 rs12816452 chr12:12833006 A/T cg04607235 chr12:12878440 APOLD1 -0.5 -7.73 -0.39 1.19e-13 Pulse pressure; LIHC cis rs12980942 0.935 rs2241718 chr19:41829606 G/A cg25627403 chr19:41769009 HNRNPUL1 0.56 6.81 0.35 4.29e-11 Coronary artery disease; LIHC cis rs7666738 0.830 rs732299 chr4:98995389 C/T cg05340658 chr4:99064831 C4orf37 0.71 12.91 0.57 2.57e-31 Colonoscopy-negative controls vs population controls; LIHC trans rs7726839 0.540 rs12517638 chr5:645484 C/T cg25482853 chr8:67687455 SGK3 0.6 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.1 0.58 4.53e-32 Prudent dietary pattern; LIHC cis rs2952156 0.684 rs881844 chr17:37810218 C/G cg00129232 chr17:37814104 STARD3 -0.59 -11.32 -0.52 1.84e-25 Asthma; LIHC cis rs11583043 0.957 rs6667932 chr1:101503755 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 8.55 0.42 4.29e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs1814175 0.684 rs1827015 chr11:49585241 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.59 0.34 1.7e-10 Height; LIHC cis rs1873147 0.569 rs8029221 chr15:63308583 C/T cg05771511 chr15:63340396 TPM1 -0.45 -5.94 -0.31 6.83e-9 Orofacial clefts; LIHC cis rs1552244 0.882 rs13062917 chr3:10017032 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg06640241 chr16:89574553 SPG7 0.87 16.45 0.66 3.23e-45 Multiple myeloma (IgH translocation); LIHC cis rs782590 0.805 rs782578 chr2:55915904 A/C cg03859395 chr2:55845619 SMEK2 0.91 15.61 0.64 7.79e-42 Metabolic syndrome; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23374814 chr5:72292757 FCHO2 0.45 6.49 0.33 3.07e-10 Pancreatic cancer; LIHC cis rs67478160 0.634 rs2295140 chr14:104216293 C/T cg01849466 chr14:104193079 ZFYVE21 -0.54 -9.41 -0.45 7.5e-19 Schizophrenia; LIHC cis rs8060686 0.641 rs113896227 chr16:68101480 C/T cg05110241 chr16:68378359 PRMT7 -0.6 -6.85 -0.35 3.54e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs9388451 0.536 rs34725880 chr6:126155237 A/G cg05901451 chr6:126070800 HEY2 -0.44 -7.53 -0.38 4.56e-13 Brugada syndrome; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.82 0.39 6.54e-14 Prudent dietary pattern; LIHC cis rs4755351 0.504 rs12225045 chr11:33346513 A/G cg05567920 chr11:33183001 CSTF3 0.4 5.73 0.3 2.24e-8 Lung cancer in ever smokers; LIHC cis rs6430585 0.941 rs10496737 chr2:136540083 A/G cg07169764 chr2:136633963 MCM6 1.04 14.31 0.61 1.02e-36 Corneal structure; LIHC cis rs2066819 0.892 rs112931321 chr12:56667894 C/T cg26714650 chr12:56694279 CS -1.4 -13.76 -0.6 1.3600000000000001e-34 Psoriasis vulgaris; LIHC cis rs7020830 0.931 rs7034554 chr9:37081301 A/G cg14294708 chr9:37120828 ZCCHC7 1.16 25.42 0.81 8.3e-81 Schizophrenia; LIHC cis rs11105298 1.000 rs11105298 chr12:89876143 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 0.58 6.66 0.34 1.09e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10779751 0.922 rs2295079 chr1:11322565 C/G cg08854313 chr1:11322531 MTOR 0.9 16.7 0.67 3.24e-46 Body mass index; LIHC cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg23978390 chr7:1156363 C7orf50 0.55 8.29 0.41 2.55e-15 Longevity;Endometriosis; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.01 22.07 0.77 9.37e-68 Height; LIHC cis rs2084898 0.891 rs2511023 chr11:120009145 A/G cg13907859 chr11:120009124 TRIM29 -0.48 -6.36 -0.33 6.46e-10 Stroke (pediatric); LIHC cis rs763121 0.785 rs6001203 chr22:39099602 T/C cg06022373 chr22:39101656 GTPBP1 0.74 14.71 0.62 2.82e-38 Menopause (age at onset); LIHC cis rs7208859 0.623 rs9891166 chr17:29111902 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12824058 0.831 rs7310433 chr12:130809289 C/T cg24838063 chr12:130822603 PIWIL1 0.67 9.96 0.47 1.1e-20 Menopause (age at onset); LIHC cis rs6882046 0.513 rs618298 chr5:88038390 A/G cg22951263 chr5:87985283 NA -0.37 -6.49 -0.33 3.06e-10 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs2439831 0.867 rs12443102 chr15:43932103 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.57 7.06 0.36 9.1e-12 Lung cancer in ever smokers; LIHC cis rs77633900 0.614 rs2468116 chr15:76870998 G/A cg21673338 chr15:77095150 SCAPER -0.49 -7.36 -0.37 1.42e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs2991971 0.967 rs12743512 chr1:45954033 A/G cg15605315 chr1:45957053 TESK2 -0.47 -6.59 -0.34 1.66e-10 High light scatter reticulocyte count; LIHC cis rs16858210 0.648 rs79478990 chr3:183587094 C/T cg25686905 chr3:183603175 PARL -0.5 -9.34 -0.45 1.31e-18 Menopause (age at onset); LIHC cis rs9328573 0.967 rs873843 chr15:100510425 C/T cg09918751 chr15:100517450 ADAMTS17 -0.54 -8.31 -0.41 2.29e-15 Urate levels in lean individuals; LIHC trans rs875971 0.642 rs35526611 chr7:66094008 C/T cg26939375 chr7:64535504 NA -0.43 -6.85 -0.35 3.37e-11 Aortic root size; LIHC cis rs8067545 0.750 rs28666381 chr17:19984809 C/G cg13482628 chr17:19912719 NA 0.48 7.96 0.4 2.51e-14 Schizophrenia; LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg22907277 chr7:1156413 C7orf50 0.54 8.44 0.42 8.97e-16 Longevity;Endometriosis; LIHC cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg04944784 chr2:26401820 FAM59B 0.71 9.3 0.45 1.7e-18 Gut microbiome composition (summer); LIHC cis rs881375 0.933 rs4837804 chr9:123705304 C/G cg14580859 chr9:123691850 NA 0.4 7.07 0.36 8.93e-12 Rheumatoid arthritis; LIHC cis rs2637266 0.905 rs60809084 chr10:78374431 A/C cg18941641 chr10:78392320 NA 0.27 5.71 0.3 2.42e-8 Pulmonary function; LIHC cis rs6762 0.748 rs7936838 chr11:839093 G/C cg15787769 chr11:842744 TSPAN4;POLR2L -0.62 -7.47 -0.37 6.92e-13 Mean platelet volume; LIHC cis rs7100689 0.646 rs2486302 chr10:82076600 G/A cg01528321 chr10:82214614 TSPAN14 0.82 11.14 0.52 8.22e-25 Post bronchodilator FEV1; LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg20295408 chr7:1910781 MAD1L1 -0.4 -5.76 -0.3 1.84e-8 Bipolar disorder and schizophrenia; LIHC cis rs870825 0.616 rs7683799 chr4:185632164 T/C cg04058563 chr4:185651563 MLF1IP 0.77 7.68 0.38 1.67e-13 Blood protein levels; LIHC cis rs7107174 1.000 rs2510043 chr11:77977481 C/G cg02023728 chr11:77925099 USP35 0.45 8.77 0.43 8.5e-17 Testicular germ cell tumor; LIHC cis rs11792861 0.926 rs76689835 chr9:111833792 G/A cg13535736 chr9:111863775 C9orf5 -0.39 -5.94 -0.31 7.12e-9 Menarche (age at onset); LIHC cis rs1371867 0.846 rs1692007 chr8:101268343 T/C cg06002616 chr8:101225028 SPAG1 0.36 6.25 0.32 1.24e-9 Atrioventricular conduction; LIHC cis rs2075671 0.903 rs11979818 chr7:100293639 A/G cg20848291 chr7:100343083 ZAN 0.47 6.96 0.35 1.79e-11 Other erythrocyte phenotypes; LIHC cis rs9790314 1.000 rs975323 chr3:161021322 A/G cg04691961 chr3:161091175 C3orf57 -0.4 -6.35 -0.32 6.7e-10 Morning vs. evening chronotype; LIHC cis rs709400 0.633 rs10141433 chr14:103962559 A/G cg26031613 chr14:104095156 KLC1 0.72 9.05 0.44 1.07e-17 Body mass index; LIHC cis rs9902453 1.000 rs9890205 chr17:28382704 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs11585357 0.895 rs72633803 chr1:17616758 G/A cg08277548 chr1:17600880 PADI3 -0.64 -6.77 -0.34 5.59e-11 Hair shape; LIHC cis rs10540 1.000 rs12801271 chr11:508720 C/T cg03576123 chr11:487126 PTDSS2 -1.09 -8.17 -0.4 5.84e-15 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02758053 chr19:56165495 U2AF2 0.51 6.6 0.34 1.58e-10 Lung function (FEV1/FVC); LIHC cis rs10508774 0.810 rs12259710 chr10:32825870 T/C cg01819863 chr10:32635814 EPC1 0.6 5.76 0.3 1.88e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs3112255 0.967 rs2971019 chr2:101298126 C/G cg06958034 chr1:23346203 KDM1A -0.46 -6.06 -0.31 3.6e-9 Intelligence (multi-trait analysis); LIHC cis rs7100689 0.646 rs7903701 chr10:82129268 T/C cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs7727544 0.684 rs272893 chr5:131663062 T/C cg24060327 chr5:131705240 SLC22A5 -0.61 -8.92 -0.43 2.96e-17 Blood metabolite levels; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 24.54 0.8 2.09e-77 Prudent dietary pattern; LIHC cis rs896854 0.517 rs1011796 chr8:95951273 A/G cg13393036 chr8:95962371 TP53INP1 0.37 7.77 0.39 9.41e-14 Type 2 diabetes; LIHC cis rs3768617 0.811 rs34721094 chr1:183051521 T/C ch.1.3577855R chr1:183094577 LAMC1 0.48 7.69 0.38 1.62e-13 Fuchs's corneal dystrophy; LIHC cis rs2070488 0.932 rs1841776 chr3:38480727 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC cis rs7953508 0.741 rs1498707 chr12:93997128 G/A cg18151635 chr12:93972918 NA -0.41 -5.93 -0.31 7.34e-9 Pubertal anthropometrics; LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs7223966 0.960 rs8082651 chr17:61675292 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.3 0.32 9.29e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7208859 0.673 rs9915963 chr17:29019643 C/T cg14067834 chr17:29058358 SUZ12P 0.57 6.04 0.31 3.99e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs919433 0.927 rs6759834 chr2:198204860 C/T cg10820045 chr2:198174542 NA -0.57 -9.35 -0.45 1.22e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11971779 0.715 rs6467856 chr7:139127299 A/C cg07862535 chr7:139043722 LUC7L2 0.6 9.99 0.48 8.86e-21 Diisocyanate-induced asthma; LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg08469215 chr1:156261351 TMEM79 0.4 6.58 0.34 1.74e-10 Tonsillectomy; LIHC cis rs7542091 0.669 rs7540534 chr1:210044824 A/T cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs9303401 0.614 rs34920953 chr17:56589406 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.9 11.72 0.54 6.56e-27 Cognitive test performance; LIHC cis rs4908768 0.501 rs7520617 chr1:8573717 C/T cg20416874 chr1:8611966 RERE -0.66 -13.86 -0.6 5.69e-35 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs12477438 0.501 rs6751927 chr2:99740175 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC trans rs8113308 0.810 rs8104281 chr19:52443019 G/A cg14959425 chr7:20447707 ITGB8 -0.48 -6.15 -0.32 2.22e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs7487075 0.780 rs12307969 chr12:46759057 G/C cg11331445 chr12:47219877 SLC38A4 0.3 6.09 0.31 3.08e-9 Itch intensity from mosquito bite; LIHC trans rs10506458 0.834 rs12426860 chr12:63387948 C/T cg22491629 chr6:157744540 C6orf35 -0.6 -10.81 -0.5 1.26e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs10540 1.000 rs79440439 chr11:478147 A/C cg03352830 chr11:487213 PTDSS2 0.78 6.18 0.32 1.79e-9 Body mass index; LIHC cis rs1043515 0.607 rs4795318 chr17:36949053 C/T cg09592244 chr17:37024020 NA 0.35 5.83 0.3 1.27e-8 Height; LIHC cis rs7959452 0.590 rs11177628 chr12:69765421 G/A cg22834771 chr12:69754056 YEATS4 -0.53 -9.35 -0.45 1.18e-18 Blood protein levels; LIHC cis rs35306767 0.714 rs66797613 chr10:1090469 C/T cg20503657 chr10:835505 NA 0.71 6.8 0.35 4.68e-11 Eosinophil percentage of granulocytes; LIHC cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 11.58 0.53 2.1e-26 Alzheimer's disease; LIHC cis rs2153535 0.526 rs7748404 chr6:8472500 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.47 -6.77 -0.34 5.57e-11 Prostate cancer; LIHC cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.22 -0.45 3.09e-18 Electroencephalogram traits; LIHC cis rs769267 1.000 rs7247309 chr19:19439631 A/T cg03709012 chr19:19516395 GATAD2A -0.91 -15.54 -0.64 1.46e-41 Tonsillectomy; LIHC cis rs939574 0.818 rs6744146 chr2:220070597 T/A cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.96 -10.46 -0.49 2.05e-22 Platelet distribution width; LIHC cis rs8072100 0.840 rs9893901 chr17:45506682 T/G cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.36 -5.78 -0.3 1.67e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7903847 0.656 rs12218483 chr10:99141484 C/T cg06359132 chr10:99160096 RRP12 -0.41 -6.05 -0.31 3.71e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs9788333 0.792 rs34479949 chr13:21895574 G/A cg02569823 chr6:5851330 NA 0.41 6.59 0.34 1.63e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6430585 0.528 rs114760827 chr2:136661110 G/A cg07169764 chr2:136633963 MCM6 1.29 21.48 0.76 2.15e-65 Corneal structure; LIHC trans rs2727020 0.553 rs10839295 chr11:49527345 A/C cg15704280 chr7:45808275 SEPT13 -0.98 -20.34 -0.74 7.59e-61 Coronary artery disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04099697 chr1:201952261 RNPEP -0.51 -6.16 -0.32 2.03e-9 Systolic blood pressure; LIHC cis rs7216064 0.953 rs62086043 chr17:65968003 A/G cg12091567 chr17:66097778 LOC651250 -0.65 -9.06 -0.44 1.01e-17 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9560113 0.573 rs9560134 chr13:112244011 C/T cg10483660 chr13:112241077 NA 0.26 6.56 0.33 2.03e-10 Menarche (age at onset); LIHC cis rs9814567 1.000 rs6763088 chr3:134254989 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6570726 0.791 rs6902404 chr6:145905254 G/A cg23711669 chr6:146136114 FBXO30 0.63 10.97 0.51 3.44e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs1401999 0.714 rs13066518 chr3:183635498 T/A cg01324343 chr3:183735012 ABCC5 0.54 8.65 0.42 2.04e-16 Anterior chamber depth; LIHC trans rs9641123 0.639 rs2677080 chr7:93256222 G/T cg09745688 chr16:2908918 PRSS22 -0.37 -6.46 -0.33 3.71e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12697442 chr11:101981167 YAP1 0.51 6.89 0.35 2.73e-11 Lung function (FEV1/FVC); LIHC cis rs4073582 0.516 rs1151539 chr11:66031660 C/T cg14036092 chr11:66035641 RAB1B 0.45 6.72 0.34 7.4e-11 Gout; LIHC cis rs7264396 0.635 rs7263302 chr20:34545858 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.72 -0.5 2.52e-23 Total cholesterol levels; LIHC cis rs17094222 0.504 rs11190661 chr10:102452136 C/T cg26540559 chr10:102447443 NA 0.4 7.73 0.39 1.24e-13 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs67981189 0.574 rs2526867 chr14:71395966 T/C cg15816911 chr14:71606274 NA -0.4 -6.32 -0.32 8.19e-10 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25654697 chr7:7680075 RPA3 0.4 6.25 0.32 1.22e-9 Cognitive function; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg16317947 chr14:104151986 KLC1 0.4 6.08 0.31 3.19e-9 Alopecia areata; LIHC trans rs4596713 0.507 rs1339546 chr9:71790297 G/A cg16512924 chr15:28394682 HERC2 0.39 6.18 0.32 1.79e-9 Headache; LIHC cis rs311392 0.554 rs377045 chr8:55098409 A/C cg20636351 chr8:55087400 NA -0.35 -7.2 -0.36 3.97e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs611744 0.967 rs673854 chr8:109191838 G/A cg18478394 chr8:109455254 TTC35 0.39 6.74 0.34 6.58e-11 Dupuytren's disease; LIHC cis rs7223966 1.000 rs6504170 chr17:61709168 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 7.03 0.36 1.11e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1949733 0.675 rs2688235 chr4:8450546 T/C cg11789530 chr4:8429930 ACOX3 0.75 10.91 0.51 5.57e-24 Response to antineoplastic agents; LIHC cis rs860295 0.702 rs11264366 chr1:155335411 A/T cg02153340 chr1:155202674 NA -0.33 -5.94 -0.31 7.11e-9 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18106171 chr1:161196208 TOMM40L 0.4 6.12 0.31 2.53e-9 Pancreatic cancer; LIHC cis rs7927592 0.913 rs7102898 chr11:68328870 G/A cg16797656 chr11:68205561 LRP5 0.5 7.73 0.39 1.25e-13 Total body bone mineral density; LIHC cis rs6430585 0.583 rs12475516 chr2:136560761 C/G cg15123519 chr2:136567270 LCT -0.41 -6.92 -0.35 2.3e-11 Corneal structure; LIHC cis rs7116495 0.737 rs661290 chr11:71766014 A/G cg10381502 chr11:71823885 C11orf51 -1.05 -9.21 -0.45 3.26e-18 Severe influenza A (H1N1) infection; LIHC cis rs3096299 0.679 rs3096322 chr16:89441123 A/G cg06640241 chr16:89574553 SPG7 -0.6 -9.48 -0.46 4.39e-19 Multiple myeloma (IgH translocation); LIHC cis rs8103278 1.000 rs7252126 chr19:46302374 T/A cg14061069 chr19:46274453 DMPK -0.54 -8.49 -0.42 6.31e-16 Coronary artery disease; LIHC cis rs10883723 0.810 rs913025 chr10:104276043 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.64 0.56 2.67e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7904368 0.524 rs7088468 chr10:16873080 C/T cg23933602 chr10:16859644 RSU1 0.44 5.93 0.31 7.5e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs10870270 1.000 rs10870270 chr10:133754334 G/A cg17892150 chr10:133769511 PPP2R2D -0.69 -13.18 -0.58 2.35e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs35110281 0.811 rs7275705 chr21:45056453 G/C cg04455712 chr21:45112962 RRP1B 0.46 7.82 0.39 6.71e-14 Mean corpuscular volume; LIHC cis rs61990749 0.597 rs1008988 chr14:78260795 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.6 9.82 0.47 3.21e-20 Fibroblast growth factor basic levels; LIHC cis rs2228479 0.850 rs17226428 chr16:89842884 T/A cg04013166 chr16:89971882 TCF25 0.5 6.13 0.31 2.39e-9 Skin colour saturation; LIHC cis rs3768617 0.510 rs10752900 chr1:183086238 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.49 0.49 1.66e-22 Fuchs's corneal dystrophy; LIHC cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11792861 0.926 rs59904140 chr9:111910051 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.39 0.41 1.34e-15 Menarche (age at onset); LIHC cis rs66887589 0.777 rs4643791 chr4:120265619 A/G cg09307838 chr4:120376055 NA -0.51 -7.79 -0.39 8.27e-14 Diastolic blood pressure; LIHC cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg06481639 chr22:41940642 POLR3H -0.71 -6.65 -0.34 1.13e-10 Vitiligo; LIHC cis rs11792861 0.926 rs75472294 chr9:111804239 G/A cg13535736 chr9:111863775 C9orf5 -0.42 -6.39 -0.33 5.4e-10 Menarche (age at onset); LIHC cis rs7412746 0.658 rs11581757 chr1:150892244 A/G cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg12379764 chr21:47803548 PCNT -0.55 -8.07 -0.4 1.18e-14 Testicular germ cell tumor; LIHC trans rs875971 0.545 rs2420612 chr7:66001812 G/A cg26939375 chr7:64535504 NA 0.39 6.17 0.32 1.91e-9 Aortic root size; LIHC cis rs7075426 1.000 rs7075426 chr10:88216402 G/A cg07322936 chr10:88137208 NA -0.49 -6.97 -0.35 1.61e-11 Migraine without aura; LIHC cis rs4638749 0.627 rs4676185 chr2:108841908 G/C cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg18230493 chr5:56204884 C5orf35 -0.45 -6.16 -0.32 2.1e-9 Initial pursuit acceleration; LIHC cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg05564831 chr3:52568323 NT5DC2 0.37 5.9 0.3 8.72e-9 Bipolar disorder; LIHC cis rs4788570 0.584 rs6499528 chr16:71672762 T/C cg06353428 chr16:71660113 MARVELD3 1.44 15.4 0.64 4.96e-41 Intelligence (multi-trait analysis); LIHC cis rs6684514 1.000 rs2296375 chr1:156309372 G/C cg16558208 chr1:156270281 VHLL 0.54 9.95 0.47 1.21e-20 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs10078 0.898 rs2241598 chr5:438564 C/T cg08916839 chr5:415575 AHRR -0.45 -9.03 -0.44 1.3e-17 Fat distribution (HIV); LIHC cis rs68170813 0.559 rs17428071 chr7:106878200 C/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs8058578 1.000 rs7198250 chr16:30746822 C/A cg00531865 chr16:30841666 NA -0.39 -6.03 -0.31 4.36e-9 Multiple myeloma; LIHC cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.75 0.57 1.02e-30 Total body bone mineral density; LIHC cis rs66573146 0.634 rs55633489 chr4:6988745 C/A cg00086871 chr4:6988644 TBC1D14 0.88 6.27 0.32 1.1e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs929354 0.742 rs6956046 chr7:156962874 G/A cg05182265 chr7:156933206 UBE3C -0.32 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs3796352 0.881 rs13100714 chr3:53074824 T/G cg07884673 chr3:53033167 SFMBT1 0.68 5.72 0.3 2.27e-8 Immune reponse to smallpox (secreted IL-2); LIHC trans rs2270927 0.790 rs4566770 chr5:75576313 A/G cg13563193 chr19:33072644 PDCD5 -0.87 -9.53 -0.46 3.05e-19 Mean corpuscular volume; LIHC cis rs881375 0.631 rs2416808 chr9:123706283 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.27 0.32 1.12e-9 Rheumatoid arthritis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.3.541014R chr3:25654052 TOP2B -0.4 -7.04 -0.36 1.08e-11 Cognitive function; LIHC cis rs611744 0.967 rs641820 chr8:109190717 T/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs7927592 0.913 rs7106010 chr11:68365212 C/T cg20283391 chr11:68216788 NA -0.51 -7.67 -0.38 1.76e-13 Total body bone mineral density; LIHC cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs12497850 0.829 rs12636030 chr3:49182237 A/G cg06212747 chr3:49208901 KLHDC8B 0.6 7.87 0.39 4.78e-14 Parkinson's disease; LIHC cis rs867186 0.614 rs17309872 chr20:33515788 A/T cg08999081 chr20:33150536 PIGU 0.65 6.0 0.31 5.11e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs2933343 0.553 rs35076317 chr3:128715535 T/C cg25356066 chr3:128598488 ACAD9 0.44 5.95 0.31 6.5e-9 IgG glycosylation; LIHC cis rs8114671 0.562 rs6087643 chr20:33474462 C/T cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.02e-19 Height; LIHC cis rs757110 0.526 rs757081 chr11:17351683 C/G cg15432903 chr11:17409602 KCNJ11 -0.53 -7.75 -0.39 1.06e-13 Type 2 diabetes; LIHC cis rs11252926 0.537 rs4554800 chr10:458477 G/T cg16346588 chr10:242978 ZMYND11 -0.38 -5.95 -0.31 6.64e-9 Psychosis in Alzheimer's disease; LIHC cis rs7131987 0.650 rs7301398 chr12:29455390 G/T cg00204748 chr12:29376779 FAR2 0.38 7.0 0.35 1.36e-11 QT interval; LIHC cis rs9427116 0.702 rs884618 chr1:154601157 A/G cg17218026 chr1:154582156 ADAR 0.34 6.53 0.33 2.44e-10 Blood protein levels; LIHC cis rs7191700 0.578 rs243327 chr16:11353304 C/T cg00044050 chr16:11439710 C16orf75 -0.45 -6.3 -0.32 9.08e-10 Multiple sclerosis; LIHC trans rs11039798 0.844 rs11040177 chr11:48976211 G/C cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC cis rs7707921 0.522 rs9293290 chr5:81474225 A/T cg15871215 chr5:81402204 ATG10 -0.62 -8.5 -0.42 5.89e-16 Breast cancer; LIHC cis rs4908768 0.501 rs4351668 chr1:8535818 C/T cg20416874 chr1:8611966 RERE -0.69 -14.74 -0.62 2.15e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4319547 0.695 rs10744211 chr12:122931820 A/G cg05707623 chr12:122985044 ZCCHC8 -0.58 -7.58 -0.38 3.38e-13 Body mass index; LIHC cis rs9911578 1.000 rs12947785 chr17:57045160 A/C cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.52e-50 Intelligence (multi-trait analysis); LIHC cis rs6598955 0.543 rs4585968 chr1:26535146 G/A cg04990556 chr1:26633338 UBXN11 0.77 11.14 0.52 8.36e-25 Obesity-related traits; LIHC cis rs7312933 0.533 rs17551006 chr12:42848738 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.96 0.4 2.55e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6061231 0.597 rs624313 chr20:60927412 G/A cg06026331 chr20:60912101 LAMA5 -0.51 -8.64 -0.42 2.16e-16 Colorectal cancer; LIHC cis rs4407350 0.721 rs105248 chr22:44891399 C/G cg26276947 chr22:44892394 LDOC1L 0.32 6.05 0.31 3.7e-9 Intelligence (multi-trait analysis); LIHC cis rs796364 1.000 rs166845 chr2:200823360 T/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.7 8.3 0.41 2.48e-15 Schizophrenia; LIHC cis rs56146971 0.763 rs34854034 chr14:91870677 A/G cg16433844 chr14:91963127 SMEK1 -0.51 -5.85 -0.3 1.14e-8 Alzheimer disease and age of onset; LIHC cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC cis rs1538970 0.748 rs11211137 chr1:46013892 T/A cg05343316 chr1:45956843 TESK2 0.61 8.1 0.4 1.01e-14 Platelet count; LIHC cis rs2243480 1.000 rs778704 chr7:65863467 T/C cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC cis rs9470366 0.816 rs7742159 chr6:36619452 A/C cg08179530 chr6:36648295 CDKN1A 0.54 6.56 0.33 1.97e-10 QRS duration; LIHC cis rs4803468 1.000 rs284650 chr19:41927129 A/G cg14132834 chr19:41945861 ATP5SL -0.46 -6.78 -0.34 5.38e-11 Height; LIHC cis rs7212590 0.748 rs7223057 chr17:57936438 G/C cg10252138 chr17:58120427 NA -0.64 -6.78 -0.34 5.15e-11 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs9858542 1.000 rs2172252 chr3:49678307 A/T cg03060546 chr3:49711283 APEH -0.63 -8.48 -0.42 6.94e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9300255 0.507 rs1615350 chr12:123650335 C/T cg05973401 chr12:123451056 ABCB9 0.52 7.49 0.38 5.93e-13 Neutrophil percentage of white cells; LIHC cis rs765787 0.530 rs28396110 chr15:45536909 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs11122272 0.735 rs2739506 chr1:231529183 T/G cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs6570726 0.935 rs413916 chr6:145831400 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.91 0.47 1.66e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.821 rs1030522 chr1:109900707 C/G cg16275483 chr1:110013120 SYPL2 -0.49 -6.12 -0.31 2.51e-9 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24763869 chr17:3572311 TMEM93;TAX1BP3 0.46 6.57 0.33 1.86e-10 Lung function (FEV1/FVC); LIHC cis rs16958440 0.541 rs13547 chr18:44634756 A/G cg17192377 chr18:44677553 HDHD2 0.5 6.31 0.32 8.73e-10 Sitting height ratio; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg03075561 chr2:201936709 FAM126B;NDUFB3 0.42 7.46 0.37 6.98e-13 Calcium levels; LIHC cis rs9534288 0.797 rs994351 chr13:46588194 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06242063 chr11:67033801 ADRBK1 0.43 6.46 0.33 3.56e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2708977 0.965 rs13019986 chr2:97243058 C/T cg01950434 chr2:97203154 ARID5A 0.51 7.74 0.39 1.11e-13 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15738916 chr2:102314495 MAP4K4 0.39 6.29 0.32 9.89e-10 Cognitive function; LIHC cis rs8180040 1.000 rs807936 chr3:47322496 C/T cg16586182 chr3:47516702 SCAP -0.55 -9.99 -0.48 8.46e-21 Colorectal cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg18481087 chr3:160474064 PPM1L -0.38 -6.28 -0.32 1.04e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs35110281 0.774 rs1378080 chr21:45011315 T/A cg04455712 chr21:45112962 RRP1B 0.44 7.47 0.37 6.64e-13 Mean corpuscular volume; LIHC cis rs1003719 0.553 rs1063948 chr21:38574674 C/G cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs6964587 1.000 rs7800582 chr7:91701346 G/A cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs909002 0.849 rs2271933 chr1:32092525 C/T cg13919466 chr1:32135498 COL16A1 0.34 6.51 0.33 2.73e-10 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.658 rs12090215 chr1:150893660 C/A cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs754466 0.606 rs3740250 chr10:79580101 C/T cg17075019 chr10:79541650 NA -0.8 -12.68 -0.57 1.86e-30 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4713118 0.586 rs6905516 chr6:28086478 A/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Parkinson's disease; LIHC cis rs6442522 1.000 rs13075773 chr3:15450569 A/T cg16303742 chr3:15540471 COLQ 0.41 6.95 0.35 1.91e-11 Uric acid levels; LIHC trans rs12753920 0.697 rs4623754 chr1:92575278 A/G cg15668468 chr10:118892869 VAX1 0.44 6.27 0.32 1.1e-9 Systemic lupus erythematosus; LIHC cis rs7945705 0.747 rs1123936 chr11:9003306 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.47 -8.45 -0.42 8.37e-16 Hemoglobin concentration; LIHC cis rs6429082 0.683 rs868815 chr1:235584543 C/G cg26050004 chr1:235667680 B3GALNT2 -0.49 -7.32 -0.37 1.81e-12 Adiposity; LIHC cis rs3824867 0.920 rs10742805 chr11:47454701 A/G cg20307385 chr11:47447363 PSMC3 0.59 8.12 0.4 8.73e-15 Mean corpuscular hemoglobin; LIHC cis rs2920503 0.959 rs2920502 chr3:12329195 G/C cg04748988 chr3:12329223 PPARG 0.54 6.99 0.35 1.44e-11 LDL cholesterol; LIHC cis rs1707322 0.752 rs11211171 chr1:46168642 A/G cg03146154 chr1:46216737 IPP 0.58 9.45 0.45 5.58e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1499614 1.000 rs1638731 chr7:66144679 C/T cg10756647 chr7:56101905 PSPH 0.98 11.62 0.53 1.57e-26 Gout; LIHC trans rs877282 0.945 rs10904556 chr10:789429 A/G cg22713356 chr15:30763199 NA 1.35 12.61 0.56 3.43e-30 Uric acid levels; LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg02990361 chr1:107599529 PRMT6 -0.66 -10.94 -0.51 4.5e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1577917 0.839 rs6454504 chr6:86580330 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.17 -0.36 4.66e-12 Response to antipsychotic treatment; LIHC cis rs561341 1.000 rs757009 chr17:30243937 A/G cg13647721 chr17:30228624 UTP6 0.77 7.77 0.39 9.53e-14 Hip circumference adjusted for BMI; LIHC cis rs8017423 0.607 rs12885664 chr14:90845697 T/C cg04374321 chr14:90722782 PSMC1 -0.46 -6.73 -0.34 7.08e-11 Mortality in heart failure; LIHC cis rs7618501 0.633 rs2008877 chr3:50162291 T/G cg21467203 chr3:49911342 NA 0.42 7.25 0.36 2.85e-12 Intelligence (multi-trait analysis); LIHC cis rs7091068 1.000 rs7091068 chr10:95420385 G/T cg20715218 chr10:95462985 C10orf4 0.58 6.2 0.32 1.63e-9 Urinary tract infection frequency; LIHC cis rs5770917 1.000 rs17848459 chr22:51012311 G/T cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.5 -6.65 -0.34 1.19e-10 Narcolepsy; LIHC cis rs600806 0.850 rs3931560 chr1:109966718 A/C cg23091122 chr1:110024289 SYPL2 -0.49 -6.46 -0.33 3.63e-10 Intelligence (multi-trait analysis); LIHC cis rs16958440 1.000 rs76594057 chr18:44637272 A/G cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC cis rs17253792 0.822 rs112238223 chr14:56056144 C/A cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.15e-10 Putamen volume; LIHC cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg13271783 chr10:134563150 INPP5A -0.53 -6.74 -0.34 6.93e-11 Migraine; LIHC cis rs311392 0.902 rs681000 chr8:55094043 C/T cg11783602 chr8:55087084 NA -0.31 -6.04 -0.31 4e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs2380220 0.541 rs72928277 chr6:96079745 G/T cg07718321 chr6:96025334 MANEA -0.53 -5.72 -0.3 2.31e-8 Behavioural disinhibition (generation interaction); LIHC cis rs10791097 0.720 rs7119425 chr11:130733185 C/T cg22079354 chr11:130786696 SNX19 0.41 5.93 0.31 7.26e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6752107 0.936 rs10195395 chr2:234206504 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.51 7.45 0.37 7.77e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2273156 0.929 rs12894820 chr14:35435525 A/G cg16230307 chr14:35515116 FAM177A1 0.39 5.76 0.3 1.85e-8 Immunoglobulin light chain (AL) amyloidosis; LIHC trans rs208515 0.556 rs1872309 chr6:66660432 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.71 7.78 0.39 8.46e-14 Exhaled nitric oxide levels; LIHC trans rs56292044 0.683 rs10112541 chr8:138777583 A/G cg05886954 chr16:3631570 BTBD12 -0.31 -6.06 -0.31 3.58e-9 Post bronchodilator FEV1/FVC ratio in COPD; LIHC cis rs9814567 0.865 rs9834981 chr3:134282279 T/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.01 -0.31 4.83e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11792861 0.816 rs28361111 chr9:111761012 A/C cg13535736 chr9:111863775 C9orf5 -0.4 -6.03 -0.31 4.29e-9 Menarche (age at onset); LIHC cis rs597539 0.654 rs655816 chr11:68626405 A/G cg06028808 chr11:68637592 NA 0.43 5.89 0.3 9.25e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg00684032 chr4:1343700 KIAA1530 0.51 7.35 0.37 1.5e-12 Obesity-related traits; LIHC cis rs3814244 0.528 rs1468487 chr12:68390382 G/A cg15249341 chr12:68405565 NA 0.34 6.87 0.35 2.97e-11 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs10751667 0.666 rs10902243 chr11:949900 T/C cg06064525 chr11:970664 AP2A2 -0.56 -15.09 -0.63 8.65e-40 Alzheimer's disease (late onset); LIHC trans rs2262909 0.962 rs11667209 chr19:22259467 A/G cg17074339 chr11:11642133 GALNTL4 0.4 6.09 0.31 3.09e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg13395646 chr4:1353034 KIAA1530 -0.45 -6.24 -0.32 1.31e-9 Longevity; LIHC cis rs243505 0.667 rs10249029 chr7:148576042 C/T cg09806900 chr7:148480153 CUL1 0.45 6.75 0.34 6.2e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17106184 1.000 rs72902760 chr1:51252471 A/C cg07174182 chr1:51127561 FAF1 -0.61 -6.65 -0.34 1.18e-10 Type 2 diabetes; LIHC cis rs17401966 0.838 rs55676616 chr1:10290126 T/C cg19773385 chr1:10388646 KIF1B -0.39 -7.15 -0.36 5.27e-12 Hepatocellular carcinoma; LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg16405210 chr4:1374714 KIAA1530 -0.89 -14.6 -0.62 7.41e-38 Longevity; LIHC cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg10802521 chr3:52805072 NEK4 -0.43 -7.2 -0.36 3.79e-12 Bipolar disorder; LIHC cis rs801193 0.613 rs2659900 chr7:66184443 G/C cg18252515 chr7:66147081 NA -0.44 -6.38 -0.33 5.63e-10 Aortic root size; LIHC cis rs9916302 0.706 rs667193 chr17:37448835 T/C cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg06481639 chr22:41940642 POLR3H 0.67 6.76 0.34 5.87e-11 Vitiligo; LIHC cis rs11122272 0.735 rs11122281 chr1:231519842 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.17 -0.48 2.11e-21 Hemoglobin concentration; LIHC cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.82e-26 Platelet count; LIHC cis rs7208859 0.623 rs9916727 chr17:29107472 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg18306943 chr3:40428807 ENTPD3 0.37 6.37 0.33 6.1e-10 Renal cell carcinoma; LIHC cis rs11098499 0.754 rs2036860 chr4:120248934 A/G cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.01e-25 Corneal astigmatism; LIHC cis rs11785400 1.000 rs6988393 chr8:143740596 A/G cg10596483 chr8:143751796 JRK 0.51 8.32 0.41 2.06e-15 Schizophrenia; LIHC cis rs6942756 0.747 rs691435 chr7:129097352 C/T cg02491457 chr7:128862824 NA 0.54 8.38 0.41 1.43e-15 White matter hyperintensity burden; LIHC cis rs7617480 0.648 rs6766238 chr3:48801929 G/A cg07636037 chr3:49044803 WDR6 0.76 9.27 0.45 2.12e-18 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs17401966 1.000 rs12734068 chr1:10376803 G/A cg15208524 chr1:10270712 KIF1B 0.46 6.77 0.34 5.67e-11 Hepatocellular carcinoma; LIHC cis rs9322817 0.691 rs9391249 chr6:105343433 T/A cg02098413 chr6:105308735 HACE1 0.41 7.67 0.38 1.75e-13 Thyroid stimulating hormone; LIHC cis rs6938 0.534 rs11854704 chr15:75221015 C/T cg14664628 chr15:75095509 CSK -0.51 -6.61 -0.34 1.52e-10 Breast cancer; LIHC cis rs2599510 0.783 rs13399071 chr2:32793783 C/T cg02381751 chr2:32503542 YIPF4 0.47 6.32 0.32 8.27e-10 Interleukin-18 levels; LIHC cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg02290350 chr8:58132656 NA 0.46 8.74 0.43 1.09e-16 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.679 rs2236450 chr21:46702553 T/C cg22633049 chr21:46681294 NA -0.33 -5.75 -0.3 2.02e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1552244 0.510 rs13075308 chr3:10034925 G/C cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs7220401 0.512 rs71371126 chr17:28002642 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.68 -8.3 -0.41 2.52e-15 Coronary artery disease; LIHC cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs6918586 0.658 rs198826 chr6:26121153 A/G cg18357526 chr6:26021779 HIST1H4A 0.55 8.01 0.4 1.83e-14 Schizophrenia; LIHC cis rs3845702 0.736 rs1904850 chr2:180852767 A/G cg01881094 chr2:180872142 CWC22 -1.14 -10.23 -0.48 1.3e-21 Schizophrenia; LIHC cis rs57221529 0.766 rs1399381 chr5:589853 G/T cg09021430 chr5:549028 NA -0.44 -8.65 -0.42 1.97e-16 Lung disease severity in cystic fibrosis; LIHC cis rs6782228 0.565 rs12695509 chr3:128417044 A/T cg16766828 chr3:128327626 NA -0.38 -6.01 -0.31 4.71e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs10540 1.000 rs61876332 chr11:487101 C/T cg03352830 chr11:487213 PTDSS2 0.68 5.86 0.3 1.08e-8 Body mass index; LIHC cis rs9790314 0.875 rs336582 chr3:161082659 C/T cg03342759 chr3:160939853 NMD3 -0.67 -9.14 -0.44 5.61e-18 Morning vs. evening chronotype; LIHC cis rs78456975 0.941 rs11886649 chr2:1567757 A/G cg01028140 chr2:1542097 TPO -0.48 -5.89 -0.3 9.04e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs6570726 0.791 rs4896820 chr6:145894957 T/C cg23711669 chr6:146136114 FBXO30 0.63 11.38 0.52 1.14e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs7224685 0.569 rs34357603 chr17:4008760 G/A cg09597638 chr17:3907349 NA 0.53 6.46 0.33 3.5e-10 Type 2 diabetes; LIHC cis rs10861342 1.000 rs10861356 chr12:105526965 G/T cg23923672 chr12:105501055 KIAA1033 0.7 8.54 0.42 4.64e-16 IgG glycosylation; LIHC cis rs17253792 0.822 rs10147688 chr14:56054642 T/C cg01858014 chr14:56050164 KTN1 -0.74 -8.25 -0.41 3.55e-15 Putamen volume; LIHC cis rs477895 0.713 rs882146 chr11:63976699 G/A cg05555928 chr11:63887634 MACROD1 0.52 6.84 0.35 3.7e-11 Mean platelet volume; LIHC trans rs7178375 1.000 rs7178533 chr15:31215976 C/G cg04373760 chr16:53404718 NA 0.58 7.28 0.37 2.29e-12 Hypertriglyceridemia; LIHC cis rs35110281 0.627 rs7282704 chr21:44966253 A/G cg01579765 chr21:45077557 HSF2BP -0.32 -6.07 -0.31 3.42e-9 Mean corpuscular volume; LIHC cis rs79057730 0.528 rs6965219 chr7:821807 C/G cg11064039 chr7:766100 PRKAR1B;HEATR2 0.8 9.01 0.44 1.47e-17 Initial pursuit acceleration; LIHC cis rs11098499 0.644 rs2389880 chr4:120559870 T/A cg09307838 chr4:120376055 NA 0.67 10.33 0.49 5.78e-22 Corneal astigmatism; LIHC cis rs1707322 0.686 rs61784833 chr1:46233772 T/C cg03146154 chr1:46216737 IPP 0.58 9.86 0.47 2.37e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2580764 0.565 rs2044291 chr2:55247954 A/G cg09592903 chr2:55203963 RTN4 -0.7 -13.0 -0.58 1.09e-31 Mean platelet volume; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg22963979 chr7:1858916 MAD1L1 -0.44 -7.12 -0.36 6.42e-12 Bipolar disorder and schizophrenia; LIHC cis rs7572733 0.534 rs1518363 chr2:198810131 C/T cg10820045 chr2:198174542 NA 0.48 7.36 0.37 1.39e-12 Dermatomyositis; LIHC cis rs600806 0.850 rs10858095 chr1:109962642 G/C cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.49 -0.38 6.08e-13 Intelligence (multi-trait analysis); LIHC cis rs9470366 0.509 rs4714001 chr6:36638175 G/A cg08179530 chr6:36648295 CDKN1A -0.57 -8.66 -0.42 1.94e-16 QRS duration; LIHC cis rs2953145 0.568 rs1133352 chr2:241522252 A/G cg07929629 chr2:241523174 NA -0.64 -9.38 -0.45 9.06e-19 Bipolar disorder; LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg22663859 chr13:21900854 NA 0.46 7.55 0.38 3.91e-13 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2842992 0.692 rs9347342 chr6:160193129 T/C cg11366901 chr6:160182831 ACAT2 0.88 15.28 0.64 1.45e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs908922 0.676 rs7529136 chr1:152516389 T/C cg20991723 chr1:152506922 NA 0.49 8.32 0.41 2.12e-15 Hair morphology; LIHC cis rs10911232 0.507 rs4652766 chr1:182994336 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC trans rs11722228 0.508 rs61335146 chr4:10130793 G/C cg26043149 chr18:55253948 FECH 0.97 14.81 0.63 1.14e-38 Gout;Urate levels;Serum uric acid levels; LIHC cis rs9814567 1.000 rs9871305 chr3:134213538 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.07 -0.31 3.42e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs116248771 0.739 rs7617983 chr3:158323716 T/A cg16708174 chr3:158430962 RARRES1 0.47 6.27 0.32 1.12e-9 diarrhoeal disease at age 2; LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs2072499 0.767 rs3001789 chr1:156197614 T/G cg25208724 chr1:156163844 SLC25A44 0.61 10.49 0.49 1.69e-22 Testicular germ cell tumor; LIHC cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg17971929 chr21:40555470 PSMG1 -0.49 -7.38 -0.37 1.22e-12 Cognitive function; LIHC cis rs9378688 1.000 rs3800184 chr6:2211690 A/T cg12303981 chr6:2244766 GMDS 0.48 6.2 0.32 1.65e-9 Caudate nucleus volume; LIHC cis rs10883723 0.668 rs12414407 chr10:104387019 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.76 -11.14 -0.52 8.27e-25 Allergic disease (asthma, hay fever or eczema); LIHC cis rs3796619 0.924 rs4690209 chr4:1077575 G/A cg27284194 chr4:1044797 NA 0.61 10.18 0.48 2.02e-21 Recombination rate (males); LIHC cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg11301795 chr4:187892539 NA -0.26 -6.99 -0.35 1.44e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg11890956 chr21:40555474 PSMG1 -0.49 -8.16 -0.4 6.35e-15 Menarche (age at onset); LIHC cis rs2243480 0.706 rs34466769 chr7:65453292 A/C cg12463550 chr7:65579703 CRCP 0.59 6.78 0.34 5.27e-11 Diabetic kidney disease; LIHC cis rs10792665 0.724 rs10898069 chr11:82711209 G/A cg24227371 chr11:82718527 RAB30 -0.38 -9.4 -0.45 8.27e-19 Obesity-related traits; LIHC cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg21782813 chr7:2030301 MAD1L1 0.46 7.69 0.38 1.59e-13 Bipolar disorder and schizophrenia; LIHC trans rs941408 1.000 rs1736181 chr19:2797703 C/T cg19676328 chr12:49525230 TUBA1B -0.42 -6.07 -0.31 3.48e-9 Total cholesterol levels; LIHC cis rs1816752 0.819 rs7985478 chr13:24991273 C/T cg22771759 chr13:24902376 NA 0.3 6.03 0.31 4.36e-9 Obesity-related traits; LIHC cis rs12893668 0.543 rs1799796 chr14:104165927 T/C cg24130564 chr14:104152367 KLC1 -0.54 -9.24 -0.45 2.63e-18 Reticulocyte count; LIHC cis rs2274273 0.870 rs61210954 chr14:55765402 T/C cg04306507 chr14:55594613 LGALS3 0.32 5.97 0.31 5.83e-9 Protein biomarker; LIHC cis rs763121 0.853 rs5750621 chr22:38956166 C/T cg06022373 chr22:39101656 GTPBP1 0.67 11.53 0.53 3.2e-26 Menopause (age at onset); LIHC cis rs5769765 0.913 rs2319462 chr22:50263370 C/T cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg03517284 chr6:25882590 NA 0.94 12.82 0.57 5.38e-31 Blood metabolite levels; LIHC cis rs1055129 0.560 rs2666003 chr17:73942976 G/A cg08125733 chr17:73851984 WBP2 0.56 8.67 0.42 1.72e-16 White matter hyperintensity burden; LIHC cis rs807029 0.577 rs750866 chr10:102761458 A/G cg27255678 chr10:102756921 LZTS2 0.5 6.9 0.35 2.49e-11 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4362 0.902 rs4351 chr17:61569732 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.38 -6.18 -0.32 1.8e-9 Blood metabolite levels; LIHC cis rs644799 1.000 rs481630 chr11:95582447 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.65 0.46 1.16e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg00280220 chr17:61926910 NA 0.43 6.75 0.34 6.18e-11 Prudent dietary pattern; LIHC cis rs7408868 0.908 rs2074619 chr19:15276919 G/A cg09752223 chr19:15281200 NOTCH3 -0.37 -5.86 -0.3 1.07e-8 Pulse pressure; LIHC cis rs78456975 1.000 rs78456975 chr2:1554190 T/G cg01028140 chr2:1542097 TPO -0.56 -6.64 -0.34 1.27e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs9291683 0.552 rs10939655 chr4:10014642 A/T cg11266682 chr4:10021025 SLC2A9 0.33 7.14 0.36 5.5e-12 Bone mineral density; LIHC cis rs244293 0.868 rs2787490 chr17:53208051 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.43 0.37 8.65e-13 Intelligence (multi-trait analysis); LIHC cis rs2777491 1.000 rs2730057 chr15:41736275 C/A cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.14 -0.44 5.46e-18 Ulcerative colitis; LIHC cis rs3770081 1.000 rs2164879 chr2:86261579 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -9.3 -0.45 1.76e-18 Facial emotion recognition (sad faces); LIHC cis rs796364 0.806 rs10931890 chr2:201102055 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -9.0 -0.44 1.63e-17 Schizophrenia; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg06558623 chr16:89946397 TCF25 0.87 13.12 0.58 3.91e-32 Skin colour saturation; LIHC cis rs4474465 0.850 rs4579956 chr11:78232445 G/C cg02023728 chr11:77925099 USP35 -0.35 -6.17 -0.32 1.92e-9 Alzheimer's disease (survival time); LIHC cis rs5770917 1.000 rs115743514 chr22:51011933 T/C cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.42 -6.14 -0.32 2.31e-9 Narcolepsy; LIHC cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg17971929 chr21:40555470 PSMG1 0.79 9.51 0.46 3.56e-19 Cognitive function; LIHC cis rs950169 0.840 rs4842853 chr15:84942304 G/T cg03959625 chr15:84868606 LOC388152 0.47 6.68 0.34 9.94e-11 Schizophrenia; LIHC cis rs12586317 0.547 rs10134907 chr14:35499211 A/C cg05294307 chr14:35346193 BAZ1A -0.5 -7.52 -0.38 4.91e-13 Psoriasis; LIHC cis rs36051895 0.632 rs10974987 chr9:5169302 G/T cg02405213 chr9:5042618 JAK2 -0.68 -10.6 -0.5 6.72e-23 Pediatric autoimmune diseases; LIHC trans rs1814175 0.904 rs1846289 chr11:49620253 G/A cg03929089 chr4:120376271 NA -0.88 -17.06 -0.68 1.15e-47 Height; LIHC cis rs1008375 0.897 rs2315554 chr4:17660407 T/C cg16339924 chr4:17578868 LAP3 0.53 6.8 0.35 4.67e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10857712 0.521 rs10857714 chr10:135235370 C/A cg15472797 chr10:135243109 NA -0.35 -5.85 -0.3 1.14e-8 Systemic lupus erythematosus; LIHC cis rs9311474 0.967 rs11717383 chr3:52287468 G/T cg18404041 chr3:52824283 ITIH1 -0.35 -5.78 -0.3 1.69e-8 Electroencephalogram traits; LIHC cis rs35883536 0.967 rs1855788 chr1:101118331 A/G cg14515779 chr1:101123966 NA -0.68 -13.56 -0.59 8.42e-34 Monocyte count; LIHC cis rs8062405 1.000 rs62036621 chr16:28833299 C/A cg00204512 chr16:28754710 NA 0.35 6.4 0.33 4.98e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7399018 0.739 rs7399073 chr12:51614050 C/A cg25754956 chr12:51612065 POU6F1 0.88 13.07 0.58 6.2e-32 Cisplatin-induced ototoxicity; LIHC cis rs12497850 0.931 rs62262517 chr3:49134914 T/G cg07636037 chr3:49044803 WDR6 0.91 15.94 0.65 3.7e-43 Parkinson's disease; LIHC cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.35 0.45 1.15e-18 Bipolar disorder; LIHC cis rs1670533 1.000 rs11731320 chr4:1057916 T/A cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC cis rs11252926 0.650 rs4880678 chr10:490472 G/A cg09445902 chr10:555545 DIP2C -0.39 -6.29 -0.32 9.75e-10 Psychosis in Alzheimer's disease; LIHC cis rs6089584 0.888 rs6061973 chr20:60610870 C/T cg06108461 chr20:60628389 TAF4 -1.01 -17.17 -0.68 4.49e-48 Body mass index; LIHC cis rs10089 0.951 rs736969 chr5:127466347 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.25e-11 Ileal carcinoids; LIHC cis rs651907 0.557 rs1031710 chr3:101463895 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.4 0.49 3.31e-22 Colorectal cancer; LIHC cis rs1801251 1.000 rs6714245 chr2:233580505 T/C cg08000102 chr2:233561755 GIGYF2 0.75 11.33 0.52 1.78e-25 Coronary artery disease; LIHC cis rs1552244 0.882 rs13063929 chr3:10010308 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.64 -9.37 -0.45 1.05e-18 Alzheimer's disease; LIHC cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg03264133 chr6:25882463 NA 0.88 11.91 0.54 1.4e-27 Blood metabolite levels; LIHC cis rs17345786 0.906 rs11708616 chr3:101231731 C/T cg11279151 chr3:101281821 RG9MTD1 -0.45 -6.09 -0.31 2.99e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs818427 0.896 rs712663 chr5:112223594 T/C cg07820702 chr5:112228657 REEP5 -0.39 -6.21 -0.32 1.55e-9 Total body bone mineral density; LIHC cis rs12291225 0.585 rs11023194 chr11:14369769 T/C cg05501817 chr11:14380813 RRAS2 -0.44 -6.21 -0.32 1.54e-9 Sense of smell; LIHC cis rs67460515 0.892 rs4856703 chr3:161047720 G/T cg17135325 chr3:160939158 NMD3 0.57 8.13 0.4 7.9e-15 Parkinson's disease; LIHC cis rs838721 0.574 rs13003198 chr2:234257105 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.48 6.89 0.35 2.63e-11 Total body bone mineral density; LIHC cis rs7106204 0.514 rs2099890 chr11:24255948 C/T ch.11.24196551F chr11:24239977 NA 0.84 12.17 0.55 1.5e-28 Response to Homoharringtonine (cytotoxicity); LIHC cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg24209194 chr3:40518798 ZNF619 -0.56 -8.4 -0.41 1.19e-15 Renal cell carcinoma; LIHC cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg03806693 chr22:41940476 POLR3H -1.08 -11.42 -0.53 8.04e-26 Vitiligo; LIHC cis rs941408 0.515 rs2110118 chr19:2775144 T/C cg02580895 chr19:2754563 NA -0.46 -6.73 -0.34 6.96e-11 Total cholesterol levels; LIHC cis rs6582630 0.502 rs7312212 chr12:38274760 T/G cg13010199 chr12:38710504 ALG10B 0.49 5.85 0.3 1.14e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs3106136 0.967 rs2306803 chr4:95161996 C/T cg11021082 chr4:95130006 SMARCAD1 -0.35 -6.56 -0.33 1.96e-10 Capecitabine sensitivity; LIHC cis rs921968 0.612 rs573555 chr2:219348888 A/C cg17980119 chr2:219472607 PLCD4 0.36 6.14 0.31 2.34e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg10360139 chr7:1886902 MAD1L1 -0.4 -6.2 -0.32 1.59e-9 Bipolar disorder and schizophrenia; LIHC cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg06238570 chr21:40685208 BRWD1 0.58 6.86 0.35 3.34e-11 Cognitive function; LIHC cis rs9902453 0.808 rs12452288 chr17:28235220 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.03e-27 Coffee consumption (cups per day); LIHC trans rs7618501 0.633 rs4688758 chr3:50028385 G/A cg21659725 chr3:3221576 CRBN 0.69 11.22 0.52 4.43e-25 Intelligence (multi-trait analysis); LIHC cis rs6867032 0.687 rs4998338 chr5:2015910 A/G cg26168224 chr5:2018326 NA 0.31 7.57 0.38 3.48e-13 Gut microbiome composition (winter); LIHC trans rs7618501 1.000 rs7372730 chr3:49790682 C/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.81 -0.63 1.12e-38 Intelligence (multi-trait analysis); LIHC cis rs67478160 0.619 rs55824307 chr14:104271207 C/T cg08213375 chr14:104286397 PPP1R13B 0.65 12.86 0.57 3.97e-31 Schizophrenia; LIHC cis rs7223966 0.960 rs11659013 chr17:61869559 C/G cg05941027 chr17:61774174 LIMD2 0.35 7.35 0.37 1.48e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9443189 0.615 rs6453829 chr6:76268509 C/T cg01950844 chr6:76311363 SENP6 0.9 11.1 0.51 1.22e-24 Prostate cancer; LIHC cis rs7131987 0.845 rs2042511 chr12:29408780 C/T cg00204748 chr12:29376779 FAR2 0.42 7.89 0.39 4.23e-14 QT interval; LIHC trans rs11098499 0.954 rs11935596 chr4:120412457 G/C cg25214090 chr10:38739885 LOC399744 0.57 9.44 0.45 6.19e-19 Corneal astigmatism; LIHC cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg20295408 chr7:1910781 MAD1L1 -0.55 -8.32 -0.41 2.07e-15 Bipolar disorder and schizophrenia; LIHC cis rs4888262 0.545 rs4243108 chr16:74692453 A/G cg01733217 chr16:74700730 RFWD3 -0.89 -18.47 -0.71 2.57e-53 Testicular germ cell tumor; LIHC cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg24549020 chr5:56110836 MAP3K1 0.5 6.35 0.32 7.05e-10 Initial pursuit acceleration; LIHC cis rs2760061 0.659 rs708107 chr1:228189495 C/T cg02753203 chr1:228287806 NA 0.45 7.29 0.37 2.18e-12 Diastolic blood pressure; LIHC cis rs2153535 0.563 rs4428546 chr6:8490376 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs3749237 0.595 rs11130199 chr3:49538799 T/C cg03060546 chr3:49711283 APEH 0.6 9.81 0.47 3.63e-20 Resting heart rate; LIHC cis rs4808199 0.948 rs1859287 chr19:19422187 T/C cg03709012 chr19:19516395 GATAD2A 0.99 15.93 0.65 4.11e-43 Nonalcoholic fatty liver disease; LIHC cis rs138880 0.542 rs9616215 chr22:50318834 C/T cg02269571 chr22:50332266 NA -0.96 -9.82 -0.47 3.21e-20 Schizophrenia; LIHC cis rs11212260 0.655 rs11212233 chr11:107306866 G/A cg25435332 chr11:107328525 CWF19L2 0.82 8.3 0.41 2.4e-15 IgG glycosylation; LIHC cis rs1023500 0.551 rs133355 chr22:42440285 G/A cg04733989 chr22:42467013 NAGA 0.67 9.71 0.46 7.44e-20 Schizophrenia; LIHC cis rs3540 0.597 rs3539 chr15:91045419 G/T cg22089800 chr15:90895588 ZNF774 -0.57 -7.94 -0.39 3.02e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg19635926 chr16:89946313 TCF25 0.47 6.29 0.32 9.52e-10 Skin colour saturation; LIHC cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs7572733 0.534 rs771009 chr2:198691082 A/G cg10820045 chr2:198174542 NA 0.46 6.91 0.35 2.4e-11 Dermatomyositis; LIHC cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg21280719 chr6:42927975 GNMT -0.31 -7.0 -0.35 1.33e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1577917 1.000 rs12207610 chr6:86688016 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.31 -0.32 8.59e-10 Response to antipsychotic treatment; LIHC trans rs9858542 0.953 rs6803222 chr3:49665976 T/G cg21659725 chr3:3221576 CRBN -0.59 -6.61 -0.34 1.5e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4319547 1.000 rs7295397 chr12:123116209 C/T cg23029597 chr12:123009494 RSRC2 -0.49 -6.86 -0.35 3.18e-11 Body mass index; LIHC cis rs7940866 0.804 rs10894289 chr11:130808685 C/T cg12179176 chr11:130786555 SNX19 0.64 9.51 0.46 3.38e-19 Schizophrenia; LIHC cis rs7412746 0.658 rs2272214 chr1:150931462 C/T cg17724175 chr1:150552817 MCL1 0.38 7.44 0.37 8.19e-13 Melanoma; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg01593421 chr7:65303149 NA 0.4 6.07 0.31 3.47e-9 Immature fraction of reticulocytes; LIHC trans rs10213084 1.000 rs9996620 chr4:147473314 C/T cg18061433 chr10:21435895 C10orf113;NEBL -0.46 -6.16 -0.32 2.02e-9 Heart rate; LIHC cis rs3796619 1.000 rs3796619 chr4:1095281 A/G cg27284194 chr4:1044797 NA 0.64 10.73 0.5 2.46e-23 Recombination rate (males); LIHC cis rs8180040 1.000 rs2302278 chr3:47361082 G/T cg02527881 chr3:46936655 PTH1R 0.31 5.9 0.3 8.87e-9 Colorectal cancer; LIHC cis rs4713118 0.513 rs149989 chr6:27998184 T/A cg16479474 chr6:28041457 NA 0.38 6.24 0.32 1.29e-9 Parkinson's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05202720 chr20:44486028 ACOT8;ZSWIM3 0.45 6.34 0.32 7.47e-10 Lung function (FEV1/FVC); LIHC cis rs10751667 0.857 rs6597952 chr11:991109 C/G ch.11.42038R chr11:967971 AP2A2 0.59 10.92 0.51 5.28e-24 Alzheimer's disease (late onset); LIHC cis rs10876993 0.728 rs1082503 chr12:58036717 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.39 -0.33 5.51e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs11077998 0.933 rs2291395 chr17:80526139 A/G cg10255544 chr17:80519551 FOXK2 0.49 8.64 0.42 2.16e-16 Reticulocyte fraction of red cells; LIHC trans rs3780486 0.846 rs12554995 chr9:33132044 A/G cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg21782813 chr7:2030301 MAD1L1 0.43 7.15 0.36 5.22e-12 Bipolar disorder and schizophrenia; LIHC cis rs10744422 0.748 rs2292138 chr12:123339712 A/G cg07706471 chr12:123319906 HIP1R -0.63 -8.28 -0.41 2.88e-15 Schizophrenia; LIHC cis rs1144333 1.000 rs76192904 chr1:76359995 C/T cg03433033 chr1:76189801 ACADM 0.55 8.26 0.41 3.14e-15 Attention function in attention deficit hyperactive disorder; LIHC cis rs7408868 1.000 rs10410514 chr19:15277610 C/T cg09752223 chr19:15281200 NOTCH3 -0.37 -5.86 -0.3 1.07e-8 Pulse pressure; LIHC cis rs4268898 0.735 rs12469585 chr2:24489054 A/T cg06627628 chr2:24431161 ITSN2 0.47 6.73 0.34 7.36e-11 Asthma; LIHC cis rs9549367 0.826 rs2302755 chr13:113898418 C/T cg00898013 chr13:113819073 PROZ -0.34 -6.19 -0.32 1.75e-9 Platelet distribution width; LIHC cis rs473651 0.935 rs578510 chr2:239343140 C/T cg21699342 chr2:239360505 ASB1 0.36 7.0 0.35 1.35e-11 Multiple system atrophy; LIHC cis rs9611565 0.500 rs2011053 chr22:42121278 G/A cg03806693 chr22:41940476 POLR3H 0.8 8.97 0.44 2e-17 Vitiligo; LIHC cis rs6977660 1.000 rs12673970 chr7:19813018 T/C cg07541023 chr7:19748670 TWISTNB 0.38 6.11 0.31 2.68e-9 Thyroid stimulating hormone; LIHC cis rs57502260 0.704 rs55975204 chr11:68249124 C/T cg20283391 chr11:68216788 NA -0.5 -6.0 -0.31 5.05e-9 Total body bone mineral density (age 45-60); LIHC trans rs1814175 0.645 rs1851849 chr11:50012164 G/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs2851682 0.706 rs2727271 chr11:61603358 A/T cg27386326 chr11:61587980 NA 0.58 9.28 0.45 2.03e-18 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs2976388 0.578 rs34956412 chr8:143822028 C/T cg06565975 chr8:143823917 SLURP1 -0.45 -8.34 -0.41 1.84e-15 Urinary tract infection frequency; LIHC cis rs4665809 0.680 rs3955310 chr2:26290828 T/G cg26119090 chr2:26468346 HADHA;HADHB -0.71 -8.89 -0.43 3.53e-17 Gut microbiome composition (summer); LIHC trans rs11690935 0.589 rs62183782 chr2:172865009 T/A cg04031134 chr7:98630788 SMURF1 -0.39 -6.05 -0.31 3.75e-9 Schizophrenia; LIHC cis rs929354 0.742 rs11980541 chr7:156988776 G/C cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg11494091 chr17:61959527 GH2 -0.55 -10.48 -0.49 1.8e-22 Prudent dietary pattern; LIHC cis rs7829975 0.522 rs6601689 chr8:8172283 C/T cg06636001 chr8:8085503 FLJ10661 0.56 7.67 0.38 1.87e-13 Mood instability; LIHC cis rs240764 0.579 rs6937520 chr6:101173735 C/T cg09795085 chr6:101329169 ASCC3 -0.43 -6.03 -0.31 4.17e-9 Neuroticism; LIHC cis rs4788570 0.655 rs7359478 chr16:71825445 A/G cg06353428 chr16:71660113 MARVELD3 1.33 14.27 0.61 1.38e-36 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.66e-17 Prudent dietary pattern; LIHC cis rs5769765 0.542 rs1535189 chr22:50249131 T/C cg02269571 chr22:50332266 NA 0.69 7.94 0.39 2.89e-14 Schizophrenia; LIHC cis rs9918079 0.542 rs6414765 chr4:15626493 G/A cg24225360 chr4:15471699 CC2D2A -0.38 -6.0 -0.31 4.96e-9 Obesity-related traits; LIHC cis rs10876993 0.890 rs10783844 chr12:58098425 A/C cg15848620 chr12:58087721 OS9 -0.56 -7.55 -0.38 3.89e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs3782089 0.744 rs11545200 chr11:65319751 G/A cg08676812 chr11:65308423 LTBP3 1.05 7.34 0.37 1.61e-12 Height; LIHC cis rs929354 0.772 rs1182360 chr7:157020550 C/G cg17757837 chr7:157058334 UBE3C 0.74 12.14 0.55 1.84e-28 Body mass index; LIHC cis rs3008870 1.000 rs3008870 chr1:67418027 C/T cg02640540 chr1:67518911 SLC35D1 0.43 5.9 0.3 8.77e-9 Lymphocyte percentage of white cells; LIHC cis rs9640161 0.789 rs3735174 chr7:150020489 T/C cg10018233 chr7:150070692 REPIN1 0.55 9.38 0.45 9.09e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs769267 0.965 rs4808200 chr19:19554803 C/T cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.21e-9 Tonsillectomy; LIHC cis rs1577917 0.740 rs9353320 chr6:86244848 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.48 9.3 0.45 1.66e-18 Response to antipsychotic treatment; LIHC cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg13271783 chr10:134563150 INPP5A -0.59 -7.11 -0.36 6.89e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9549367 0.826 rs2287249 chr13:113889355 A/G cg18105134 chr13:113819100 PROZ -0.68 -11.73 -0.54 6.2e-27 Platelet distribution width; LIHC cis rs10504073 0.647 rs4873312 chr8:49991145 A/G cg00325661 chr8:49890786 NA 0.33 7.51 0.38 5.11e-13 Blood metabolite ratios; LIHC cis rs3768617 0.510 rs1413390 chr1:183096634 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs4478037 0.749 rs6550204 chr3:33107645 C/T cg27203090 chr3:33138513 GLB1;TMPPE 0.5 6.14 0.32 2.24e-9 Major depressive disorder; LIHC cis rs2540917 0.765 rs243080 chr2:60614572 G/A cg00543073 chr2:60773386 BCL11A -0.32 -6.31 -0.32 8.43e-10 Mean corpuscular volume; LIHC cis rs12971120 0.891 rs4891557 chr18:72170299 C/T cg26446133 chr18:72167187 CNDP2 -0.8 -14.76 -0.62 1.75e-38 Refractive error; LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg21448741 chr8:58168803 NA 0.37 5.95 0.31 6.81e-9 Developmental language disorder (linguistic errors); LIHC cis rs6456156 0.586 rs6456149 chr6:167463902 T/C cg23791538 chr6:167370224 RNASET2 -0.53 -8.59 -0.42 3.07e-16 Primary biliary cholangitis; LIHC cis rs9790314 1.000 rs2218803 chr3:161047973 T/G cg04691961 chr3:161091175 C3orf57 -0.42 -6.64 -0.34 1.23e-10 Morning vs. evening chronotype; LIHC cis rs5769765 0.773 rs9616383 chr22:50313014 T/C cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs8017423 0.967 rs11849641 chr14:90727647 T/C cg04374321 chr14:90722782 PSMC1 0.78 15.15 0.63 4.85e-40 Mortality in heart failure; LIHC cis rs700651 0.789 rs6715070 chr2:198898265 A/G cg03934865 chr2:198174659 NA -0.43 -6.22 -0.32 1.46e-9 Intracranial aneurysm; LIHC cis rs6088813 1.000 rs62211529 chr20:33959315 T/C cg14752227 chr20:34000481 UQCC -0.4 -5.78 -0.3 1.7e-8 Height; LIHC cis rs2629540 0.889 rs7090422 chr10:126439361 T/A cg08799069 chr10:126477246 METTL10 -0.53 -8.56 -0.42 3.78e-16 Cocaine dependence; LIHC cis rs6466055 0.720 rs7800928 chr7:105007470 T/C cg04380332 chr7:105027541 SRPK2 -0.37 -6.85 -0.35 3.39e-11 Schizophrenia; LIHC cis rs8180040 1.000 rs4858888 chr3:47405305 C/T cg16586182 chr3:47516702 SCAP 0.58 10.76 0.5 1.81e-23 Colorectal cancer; LIHC cis rs716804 0.740 rs726102 chr11:10283978 G/A cg01453529 chr11:10209919 SBF2 -0.3 -6.08 -0.31 3.23e-9 Neuroticism; LIHC trans rs7937682 0.924 rs10891288 chr11:111552053 G/T cg18187862 chr3:45730750 SACM1L -0.57 -6.2 -0.32 1.67e-9 Primary sclerosing cholangitis; LIHC cis rs1552244 0.882 rs13088350 chr3:10044626 T/C cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs1003719 0.788 rs8133549 chr21:38447489 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs10751667 0.666 rs7105477 chr11:964271 C/G cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.77e-13 Alzheimer's disease (late onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24536044 chr1:244816274 PPPDE1 -0.48 -6.97 -0.35 1.62e-11 Pancreatic cancer; LIHC trans rs11722228 0.508 rs2241473 chr4:10085949 G/A cg26043149 chr18:55253948 FECH 0.78 12.04 0.55 4.31e-28 Gout;Urate levels;Serum uric acid levels; LIHC cis rs858239 0.509 rs6975524 chr7:23186452 T/C cg23682824 chr7:23144976 KLHL7 0.43 6.47 0.33 3.41e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs910316 0.763 rs175047 chr14:75479039 C/G cg11812906 chr14:75593930 NEK9 -0.72 -13.49 -0.59 1.49e-33 Height; LIHC cis rs67460515 0.892 rs4856756 chr3:160999414 G/A cg17135325 chr3:160939158 NMD3 0.53 7.65 0.38 2.02e-13 Parkinson's disease; LIHC cis rs4790333 0.537 rs2447106 chr17:2257819 A/T cg02569219 chr17:2266849 SGSM2 -0.41 -6.33 -0.32 7.83e-10 Proinsulin levels; LIHC cis rs6570726 0.818 rs9390338 chr6:145908265 A/G cg23711669 chr6:146136114 FBXO30 0.7 11.65 0.53 1.22e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs17401966 0.867 rs10492973 chr1:10398985 T/C cg19773385 chr1:10388646 KIF1B -0.39 -6.99 -0.35 1.46e-11 Hepatocellular carcinoma; LIHC cis rs2274273 0.870 rs8013713 chr14:55841252 A/G cg01864836 chr14:55583639 NA 0.38 6.69 0.34 9.37e-11 Protein biomarker; LIHC cis rs963731 0.649 rs2373495 chr2:39254627 C/G cg04010122 chr2:39346883 SOS1 -0.64 -5.79 -0.3 1.56e-8 Corticobasal degeneration; LIHC cis rs477692 0.637 rs2388331 chr10:131314173 G/A cg05714579 chr10:131428358 MGMT 0.41 6.64 0.34 1.25e-10 Response to temozolomide; LIHC cis rs6061231 0.631 rs2427317 chr20:60975725 C/T cg24112000 chr20:60950667 NA -0.61 -9.86 -0.47 2.42e-20 Colorectal cancer; LIHC cis rs919433 0.680 rs2565160 chr2:198286474 A/G cg10820045 chr2:198174542 NA 0.56 9.11 0.44 7.29e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg18252515 chr7:66147081 NA 1.28 16.93 0.68 3.98e-47 Diabetic kidney disease; LIHC cis rs735396 0.731 rs1182933 chr12:121454622 C/T cg25281562 chr12:121454272 C12orf43 0.36 6.28 0.32 1.02e-9 N-glycan levels; LIHC cis rs9612 1.000 rs12669 chr19:44235535 G/A cg08581076 chr19:44259116 C19orf61 0.61 7.15 0.36 5.16e-12 Exhaled nitric oxide output; LIHC cis rs4243830 0.850 rs7536908 chr1:6607814 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.8 -9.94 -0.47 1.29e-20 Body mass index; LIHC cis rs778371 0.676 rs11688166 chr2:233566210 A/G cg08000102 chr2:233561755 GIGYF2 0.76 9.15 0.44 5.1e-18 Schizophrenia; LIHC cis rs17401966 0.931 rs4846205 chr1:10310214 A/T cg19773385 chr1:10388646 KIF1B -0.4 -7.2 -0.36 3.75e-12 Hepatocellular carcinoma; LIHC trans rs72634258 0.836 rs9658012 chr1:7989022 C/T cg01095510 chr12:26267286 NA 0.54 6.28 0.32 9.99e-10 Inflammatory bowel disease; LIHC cis rs7131987 0.621 rs11050181 chr12:29467669 C/T cg05697976 chr12:29376483 FAR2 0.3 5.99 0.31 5.44e-9 QT interval; LIHC cis rs28735056 0.592 rs12455965 chr18:77688830 G/C cg20368463 chr18:77673604 PQLC1 -0.51 -9.35 -0.45 1.2e-18 Schizophrenia; LIHC trans rs6512645 1.000 rs6512645 chr20:49087012 A/G cg13303475 chr12:104234557 NT5DC3 0.44 6.18 0.32 1.83e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6426558 0.537 rs2813969 chr1:227404082 T/C cg10327440 chr1:227177885 CDC42BPA 0.41 6.25 0.32 1.2e-9 Neutrophil percentage of white cells; LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg04013166 chr16:89971882 TCF25 0.61 8.13 0.4 7.75e-15 Skin colour saturation; LIHC cis rs6752107 0.967 rs56227616 chr2:234157741 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.53 7.9 0.39 3.78e-14 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1707322 0.686 rs3014251 chr1:46077428 G/C cg06784218 chr1:46089804 CCDC17 -0.42 -7.6 -0.38 2.96e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6912958 0.516 rs242278 chr6:88047059 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.46 0.37 7.38e-13 Monocyte percentage of white cells; LIHC cis rs7192750 0.586 rs8044342 chr16:71869532 A/G cg06353428 chr16:71660113 MARVELD3 0.74 8.24 0.41 3.8e-15 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs7100689 0.784 rs7081903 chr10:82162509 T/C cg00277334 chr10:82204260 NA -0.58 -7.47 -0.37 6.66e-13 Post bronchodilator FEV1; LIHC cis rs2637266 0.935 rs1907300 chr10:78325091 A/G cg18941641 chr10:78392320 NA 0.29 5.96 0.31 6.34e-9 Pulmonary function; LIHC cis rs79149102 0.579 rs7342601 chr15:75306795 G/T cg16226627 chr15:75307476 SCAMP5 -0.52 -9.59 -0.46 1.88e-19 Lung cancer; LIHC cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 7.9 0.39 3.85e-14 Platelet count; LIHC cis rs8062405 0.728 rs9931989 chr16:28906084 G/C cg00204512 chr16:28754710 NA -0.35 -6.22 -0.32 1.48e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9596863 0.898 rs9568905 chr13:54330289 G/A ch.13.53330881F chr13:54432880 NA 0.44 6.11 0.31 2.72e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9309473 1.000 rs6740223 chr2:73653332 T/C cg20560298 chr2:73613845 ALMS1 -0.56 -7.09 -0.36 7.86e-12 Metabolite levels; LIHC cis rs7617773 0.817 rs936427 chr3:48301074 A/G cg11946769 chr3:48343235 NME6 -0.91 -11.39 -0.52 1.04e-25 Coronary artery disease; LIHC trans rs7721647 0.810 rs16876880 chr5:90796839 T/A cg10859192 chr12:54071672 ATP5G2 -0.41 -6.07 -0.31 3.32e-9 Breast cancer; LIHC cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg03517284 chr6:25882590 NA -0.66 -8.49 -0.42 6.36e-16 Intelligence (multi-trait analysis); LIHC cis rs769267 0.930 rs6909 chr19:19619542 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.4 6.08 0.31 3.17e-9 Tonsillectomy; LIHC cis rs2354432 0.556 rs2353977 chr1:146839637 G/T cg25205988 chr1:146714368 CHD1L 0.85 9.64 0.46 1.32e-19 Mitochondrial DNA levels; LIHC cis rs68170813 0.559 rs74906766 chr7:106885236 T/A cg02696742 chr7:106810147 HBP1 -0.5 -5.86 -0.3 1.07e-8 Coronary artery disease; LIHC cis rs7100689 0.725 rs2185425 chr10:82139941 T/C cg01528321 chr10:82214614 TSPAN14 0.9 13.15 0.58 2.99e-32 Post bronchodilator FEV1; LIHC trans rs875971 0.545 rs73376401 chr7:65639828 G/A cg26939375 chr7:64535504 NA 0.4 6.36 0.33 6.33e-10 Aortic root size; LIHC cis rs6912958 0.559 rs183599 chr6:88061024 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.38 7.54 0.38 4.32e-13 Monocyte percentage of white cells; LIHC cis rs8067354 0.645 rs2645489 chr17:57883371 T/G cg02344993 chr17:57696989 CLTC 0.7 11.97 0.54 8.2e-28 Hemoglobin concentration; LIHC cis rs765787 0.530 rs11855435 chr15:45522117 G/A cg25801113 chr15:45476975 SHF 0.38 6.51 0.33 2.69e-10 Uric acid levels; LIHC cis rs7592578 0.679 rs4287794 chr2:191327147 T/C cg27211696 chr2:191398769 TMEM194B -0.54 -7.07 -0.36 8.89e-12 Diastolic blood pressure; LIHC cis rs11958404 0.932 rs72816581 chr5:157432591 T/A cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs6545883 0.825 rs4672426 chr2:61457148 G/A cg14146966 chr2:61757674 XPO1 -0.43 -7.2 -0.36 3.95e-12 Tuberculosis; LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs2163237 0.965 rs10190131 chr2:55983605 A/G cg18811423 chr2:55921094 PNPT1 -0.48 -6.64 -0.34 1.25e-10 IgG glycosylation; LIHC cis rs9427116 0.967 rs7547072 chr1:154639255 A/G cg24304309 chr1:154577895 ADAR -0.31 -5.83 -0.3 1.3e-8 Blood protein levels; LIHC cis rs1538970 0.884 rs1771551 chr1:45883643 C/G cg24296786 chr1:45957014 TESK2 -0.51 -7.6 -0.38 2.78e-13 Platelet count; LIHC cis rs155076 0.666 rs2015241 chr13:21888254 A/G cg14456004 chr13:21872349 NA 1.36 14.47 0.62 2.31e-37 White matter hyperintensity burden; LIHC cis rs3106136 0.967 rs7435106 chr4:95169772 T/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.93 -0.39 3.1e-14 Capecitabine sensitivity; LIHC cis rs6738485 0.507 rs66569888 chr2:106886967 G/A cg16099169 chr2:106886729 NA -0.94 -10.13 -0.48 2.96e-21 Pursuit maintenance gain;Pursuit maintenance gain in psychotic disorders; LIHC cis rs8010715 0.848 rs8009511 chr14:24593980 G/A cg23112188 chr14:24563095 PCK2 -0.29 -6.04 -0.31 4.13e-9 IgG glycosylation; LIHC cis rs5769765 0.773 rs58375955 chr22:50312630 A/G cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs921968 0.643 rs1850169 chr2:219487299 A/T cg18887096 chr2:219472410 PLCD4 0.34 5.87 0.3 1.04e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs4718428 0.705 rs68168107 chr7:66255238 G/A cg18252515 chr7:66147081 NA -0.7 -9.52 -0.46 3.31e-19 Corneal structure; LIHC cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs9457247 0.967 rs424185 chr6:167410907 C/T cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC cis rs769267 0.929 rs2965180 chr19:19491973 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 -0.39 -5.94 -0.31 6.83e-9 Tonsillectomy; LIHC cis rs11098499 0.954 rs9998585 chr4:120396802 T/A cg09307838 chr4:120376055 NA 0.76 12.3 0.55 4.72e-29 Corneal astigmatism; LIHC cis rs7246657 0.941 rs12982333 chr19:37794724 A/G cg23950597 chr19:37808831 NA -0.5 -6.36 -0.33 6.62e-10 Coronary artery calcification; LIHC cis rs1153858 0.848 rs9806699 chr15:45740392 G/A cg26924012 chr15:45694286 SPATA5L1 0.69 12.21 0.55 1.01e-28 Homoarginine levels; LIHC cis rs9640161 0.750 rs3800780 chr7:150027284 C/A cg27494647 chr7:150038898 RARRES2 0.32 5.83 0.3 1.26e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs12594515 1.000 rs12185095 chr15:45994635 G/T cg01629716 chr15:45996671 NA 0.5 8.94 0.44 2.55e-17 Waist circumference;Weight; LIHC trans rs2504916 0.830 rs2504934 chr6:160781666 A/G cg18578343 chr6:166797258 BRP44L -0.48 -6.46 -0.33 3.65e-10 Response to hepatitis C treatment; LIHC cis rs3823572 0.564 rs2346275 chr7:133662166 G/A cg03336402 chr7:133662267 EXOC4 -0.49 -6.07 -0.31 3.47e-9 Intelligence (multi-trait analysis); LIHC trans rs867371 1.000 rs8041924 chr15:82473661 A/T cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.75 -0.34 6.31e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs11098499 0.739 rs9996382 chr4:120151012 C/T cg25214090 chr10:38739885 LOC399744 0.38 6.27 0.32 1.07e-9 Corneal astigmatism; LIHC trans rs62103177 0.713 rs62103186 chr18:77627574 G/C cg05926928 chr17:57297772 GDPD1 1.11 11.42 0.53 8.64e-26 Opioid sensitivity; LIHC trans rs7615952 0.673 rs115942855 chr3:125601960 G/A cg07211511 chr3:129823064 LOC729375 -0.9 -8.88 -0.43 3.85e-17 Blood pressure (smoking interaction); LIHC cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg25894440 chr7:65020034 NA 0.52 6.05 0.31 3.73e-9 Diabetic kidney disease; LIHC cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs12286929 0.802 rs12787954 chr11:115020328 T/C cg04055981 chr11:115044050 NA 0.39 5.74 0.3 2.12e-8 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2749592 0.611 rs2505199 chr10:38392457 G/A cg00409905 chr10:38381863 ZNF37A -0.52 -8.41 -0.41 1.12e-15 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs801193 1.000 rs6958520 chr7:66151453 T/C cg18876405 chr7:65276391 NA 0.43 7.36 0.37 1.34e-12 Aortic root size; LIHC cis rs7100689 0.784 rs7895042 chr10:82095276 G/A cg00277334 chr10:82204260 NA -0.55 -6.8 -0.35 4.67e-11 Post bronchodilator FEV1; LIHC cis rs7618501 0.573 rs7634917 chr3:50049299 T/G cg21467203 chr3:49911342 NA 0.43 7.67 0.38 1.85e-13 Intelligence (multi-trait analysis); LIHC cis rs7193541 0.646 rs4888267 chr16:74687906 A/G cg01733217 chr16:74700730 RFWD3 0.92 22.75 0.78 2.09e-70 Multiple myeloma; LIHC cis rs9733 0.650 rs3738485 chr1:150552392 C/G cg13175981 chr1:150552382 MCL1 0.62 9.66 0.46 1.13e-19 Tonsillectomy; LIHC cis rs6582630 0.560 rs4882325 chr12:38510037 C/T cg26384229 chr12:38710491 ALG10B -0.49 -6.88 -0.35 2.78e-11 Drug-induced liver injury (flucloxacillin); LIHC trans rs56011263 0.687 rs4690187 chr4:703813 C/T cg12575136 chr18:32820987 ZNF397 0.48 7.16 0.36 5.09e-12 White blood cell count; LIHC cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg04944784 chr2:26401820 FAM59B -0.77 -9.44 -0.45 6.02e-19 Gut microbiome composition (summer); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg26841383 chr13:97999364 MBNL2 0.42 6.27 0.32 1.09e-9 Immature fraction of reticulocytes; LIHC cis rs1707322 0.752 rs10789467 chr1:46118745 C/G cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4819052 0.851 rs2838865 chr21:46712299 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.56 7.9 0.39 3.83e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3749237 0.595 rs6797765 chr3:49423976 A/G cg07636037 chr3:49044803 WDR6 0.49 7.46 0.37 7.04e-13 Resting heart rate; LIHC cis rs910316 1.000 rs3742778 chr14:75538217 A/C cg11812906 chr14:75593930 NEK9 -0.76 -15.2 -0.63 3.2e-40 Height; LIHC cis rs7772486 0.754 rs9399561 chr6:145955687 C/G cg23711669 chr6:146136114 FBXO30 0.73 13.49 0.59 1.45e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs3815700 1.000 rs7248273 chr19:33096816 C/T cg13320555 chr19:33072785 PDCD5 0.49 7.33 0.37 1.69e-12 Eosinophilic esophagitis; LIHC cis rs9814567 0.778 rs4955546 chr3:134334738 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.56 -9.02 -0.44 1.34e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9303280 0.806 rs4795399 chr17:38061439 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.8 0.3 1.52e-8 Self-reported allergy; LIHC cis rs4713118 0.662 rs175954 chr6:28011585 A/G cg16479474 chr6:28041457 NA 0.47 7.07 0.36 9.04e-12 Parkinson's disease; LIHC cis rs694739 0.892 rs647152 chr11:64109118 T/G cg23796481 chr11:64053134 BAD;GPR137 0.51 7.32 0.37 1.75e-12 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs3859192 0.561 rs9916158 chr17:38182229 G/T cg17344932 chr17:38183730 MED24;SNORD124 0.79 16.18 0.66 3.92e-44 White blood cell count; LIHC cis rs9443189 0.570 rs6903124 chr6:76290079 A/C cg01950844 chr6:76311363 SENP6 0.9 11.22 0.52 4.37e-25 Prostate cancer; LIHC cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg22907277 chr7:1156413 C7orf50 0.45 6.44 0.33 4.14e-10 Longevity;Endometriosis; LIHC cis rs7520050 0.931 rs11211224 chr1:46384388 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.6e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1003719 0.680 rs2835670 chr21:38581114 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.23 -0.48 1.3e-21 Eye color traits; LIHC cis rs2404602 0.647 rs3812909 chr15:77176200 A/T cg23625390 chr15:77176239 SCAPER -0.57 -9.72 -0.47 6.83e-20 Blood metabolite levels; LIHC cis rs1577917 0.958 rs11755642 chr6:86450066 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.81 -0.39 7.21e-14 Response to antipsychotic treatment; LIHC cis rs6912958 0.781 rs13193380 chr6:88297057 G/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg06634786 chr22:41940651 POLR3H -0.71 -7.81 -0.39 7.26e-14 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13959152 chr12:100535986 UHRF1BP1L 0.47 6.54 0.33 2.31e-10 Pancreatic cancer; LIHC cis rs7903847 0.642 rs11189191 chr10:99148796 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.61 -0.34 1.45e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs57221529 0.766 rs12519763 chr5:559145 C/T cg09021430 chr5:549028 NA -0.46 -9.13 -0.44 5.9e-18 Lung disease severity in cystic fibrosis; LIHC cis rs4906332 0.754 rs34235720 chr14:104004968 C/T cg04998671 chr14:104000505 TRMT61A -0.57 -7.21 -0.36 3.54e-12 Coronary artery disease; LIHC cis rs35110281 0.777 rs7276215 chr21:44990697 A/G cg04455712 chr21:45112962 RRP1B 0.48 8.13 0.4 8.23e-15 Mean corpuscular volume; LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg17076397 chr5:10353763 MARCH6 -0.45 -6.07 -0.31 3.4e-9 Thyroid stimulating hormone; LIHC cis rs9810089 0.814 rs866758 chr3:136117870 G/C cg21827317 chr3:136751795 NA 0.44 5.93 0.31 7.45e-9 Gestational age at birth (child effect); LIHC cis rs6714710 0.603 rs58546246 chr2:98521823 C/A cg26665480 chr2:98280029 ACTR1B 0.44 6.2 0.32 1.64e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs7666738 0.606 rs28481322 chr4:99086638 T/C cg05340658 chr4:99064831 C4orf37 0.65 11.68 0.53 9.06e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs2727020 0.615 rs10128582 chr11:49447424 C/T cg18944383 chr4:111397179 ENPEP 0.24 6.17 0.32 1.9e-9 Coronary artery disease; LIHC cis rs9790314 0.967 rs1382427 chr3:161032576 T/C cg04691961 chr3:161091175 C3orf57 -0.42 -6.53 -0.33 2.34e-10 Morning vs. evening chronotype; LIHC cis rs6952808 1.000 rs4721121 chr7:1892565 A/G cg02951883 chr7:2050386 MAD1L1 -0.53 -7.9 -0.39 3.74e-14 Bipolar disorder and schizophrenia; LIHC cis rs7223966 1.000 rs9909992 chr17:61731931 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.42 0.33 4.58e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7927592 0.913 rs4084149 chr11:68288567 A/G cg20283391 chr11:68216788 NA -0.52 -7.75 -0.39 1.05e-13 Total body bone mineral density; LIHC cis rs12364620 1 rs12364620 chr11:68252123 T/G cg01657329 chr11:68192670 LRP5 -0.45 -5.86 -0.3 1.1e-8 Total body bone mineral density (age 0-15); LIHC cis rs8049040 0.967 rs8050135 chr16:71472571 T/C cg06353428 chr16:71660113 MARVELD3 -0.58 -6.17 -0.32 1.88e-9 Blood protein levels; LIHC cis rs12079745 0.793 rs12061405 chr1:169208368 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.78 -6.9 -0.35 2.59e-11 QT interval; LIHC cis rs2836950 0.545 rs11701805 chr21:40618683 T/C cg06238570 chr21:40685208 BRWD1 -0.44 -7.08 -0.36 8.36e-12 Menarche (age at onset); LIHC cis rs986417 0.901 rs2351172 chr14:61008687 A/G cg27398547 chr14:60952738 C14orf39 0.74 8.02 0.4 1.71e-14 Gut microbiota (bacterial taxa); LIHC cis rs637571 0.584 rs659824 chr11:65636509 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.5 -7.46 -0.37 7.36e-13 Eosinophil percentage of white cells; LIHC cis rs1949733 1.000 rs3103071 chr4:8508579 C/G cg11789530 chr4:8429930 ACOX3 -0.77 -11.46 -0.53 5.98e-26 Response to antineoplastic agents; LIHC cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg12463550 chr7:65579703 CRCP 0.69 7.15 0.36 5.29e-12 Diabetic kidney disease; LIHC cis rs1371867 0.846 rs1660326 chr8:101290447 G/A cg06636551 chr8:101224915 SPAG1 -0.51 -9.11 -0.44 6.97e-18 Atrioventricular conduction; LIHC cis rs798554 0.567 rs1182194 chr7:2868824 C/G cg13628971 chr7:2884303 GNA12 0.39 5.89 0.3 9.27e-9 Height; LIHC cis rs2841277 0.802 rs2841269 chr14:105386149 C/G cg15352829 chr14:105391018 PLD4 -0.42 -8.51 -0.42 5.39e-16 Rheumatoid arthritis; LIHC cis rs7520050 0.931 rs11211224 chr1:46384388 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.37e-8 Red blood cell count;Reticulocyte count; LIHC cis rs12478296 1.000 rs73007138 chr2:243007041 C/T cg05760424 chr2:242988095 NA -0.5 -6.3 -0.32 9.04e-10 Obesity-related traits; LIHC cis rs9324022 0.929 rs9635298 chr14:101172542 C/T cg18089426 chr14:101175970 NA 0.53 6.37 0.33 6.05e-10 Plateletcrit; LIHC cis rs1707322 0.964 rs10437063 chr1:46273666 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.19 0.32 1.71e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs56104184 0.830 rs45589039 chr19:49355385 C/T cg15549821 chr19:49342101 PLEKHA4 -1.17 -9.72 -0.47 7.12e-20 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17272331 chr6:101328506 ASCC3 0.47 6.33 0.32 7.61e-10 Pancreatic cancer; LIHC cis rs4409675 0.576 rs7533918 chr1:28230667 G/A cg23691781 chr1:28212827 C1orf38 0.3 7.34 0.37 1.6e-12 Corneal astigmatism; LIHC cis rs34375054 0.672 rs58416336 chr12:125606428 G/T cg25124228 chr12:125621409 AACS -0.39 -6.68 -0.34 9.6e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg03806693 chr22:41940476 POLR3H -0.98 -10.61 -0.5 6.25e-23 Vitiligo; LIHC cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs1707322 0.752 rs61784798 chr1:46173481 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1568889 0.838 rs7121937 chr11:28359858 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 14.48 0.62 2.2e-37 Bipolar disorder; LIHC trans rs561341 0.769 rs12941700 chr17:30185022 A/G cg20587970 chr11:113659929 NA 0.62 6.53 0.33 2.39e-10 Hip circumference adjusted for BMI; LIHC cis rs1577917 1.000 rs6454513 chr6:86720049 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.42 7.81 0.39 6.91e-14 Response to antipsychotic treatment; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg20300129 chr6:35058181 ANKS1A 0.4 6.13 0.31 2.42e-9 Lung function (FEV1); LIHC cis rs921968 0.541 rs496674 chr2:219432569 G/A cg02176678 chr2:219576539 TTLL4 0.53 7.43 0.37 8.67e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs597539 0.652 rs513359 chr11:68669496 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.78 -11.17 -0.52 6.71e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs5769765 0.955 rs7511159 chr22:50307896 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -9.3 -0.45 1.77e-18 Schizophrenia; LIHC cis rs2075165 0.901 rs759329 chr1:156230936 A/G cg10096929 chr1:156261403 TMEM79 0.37 6.02 0.31 4.39e-9 Tonsillectomy; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs1144333 0.655 rs114383686 chr1:76325327 C/T cg22875332 chr1:76189707 ACADM 0.44 6.83 0.35 3.94e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs6089584 1.000 rs6089580 chr20:60558976 G/A cg06108461 chr20:60628389 TAF4 -0.88 -13.71 -0.6 2.16e-34 Body mass index; LIHC cis rs34172651 0.545 rs7185291 chr16:24714679 C/T cg00339695 chr16:24857497 SLC5A11 -0.36 -6.16 -0.32 2e-9 Intelligence (multi-trait analysis); LIHC cis rs826838 0.935 rs11183940 chr12:38851642 A/G cg13010199 chr12:38710504 ALG10B 0.61 7.5 0.38 5.64e-13 Heart rate; LIHC cis rs2115630 1.000 rs8037423 chr15:85355494 C/T cg12501888 chr15:85177176 SCAND2 -0.49 -7.56 -0.38 3.86e-13 P wave terminal force; LIHC cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg11764359 chr7:65958608 NA -0.57 -5.92 -0.31 7.72e-9 Diabetic kidney disease; LIHC cis rs4903214 0.895 rs1548767 chr14:74694957 C/T cg11132536 chr14:74711944 VSX2 -0.27 -6.26 -0.32 1.14e-9 Inflammatory bowel disease; LIHC cis rs12611088 0.571 rs7252955 chr19:44021766 A/T cg13740135 chr19:44006432 PHLDB3 -0.41 -5.96 -0.31 6.23e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs2067615 0.579 rs4385986 chr12:107133775 C/T cg15890332 chr12:107067104 RFX4 0.27 6.34 0.32 7.38e-10 Heart rate; LIHC cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg09060608 chr5:178986726 RUFY1 -0.41 -6.16 -0.32 2.01e-9 Lung cancer; LIHC cis rs11864453 0.749 rs7192730 chr16:72124219 T/C cg16558253 chr16:72132732 DHX38 -0.51 -8.1 -0.4 9.86e-15 Fibrinogen levels; LIHC cis rs826838 0.967 rs1352122 chr12:39130885 G/A cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs8078723 0.866 rs7502514 chr17:38188844 A/G cg17467752 chr17:38218738 THRA -0.77 -14.65 -0.62 4.65e-38 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs1059312 0.808 rs11059921 chr12:129289919 C/T cg09035930 chr12:129282057 SLC15A4 0.59 11.1 0.51 1.21e-24 Systemic lupus erythematosus; LIHC trans rs116095464 0.558 rs57335027 chr5:262907 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs7072216 0.763 rs6584198 chr10:100169906 G/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs1697938 0.840 rs1806513 chr5:40869406 T/C cg01087697 chr5:40835557 RPL37 -0.49 -6.03 -0.31 4.33e-9 Multiple system atrophy; LIHC cis rs7772486 0.875 rs2748501 chr6:146312258 G/A cg23711669 chr6:146136114 FBXO30 0.65 11.42 0.53 8.59e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7131987 0.834 rs11050167 chr12:29426387 C/T cg00204748 chr12:29376779 FAR2 0.41 7.22 0.36 3.49e-12 QT interval; LIHC cis rs9918079 0.506 rs10214 chr4:15606431 T/C cg04067612 chr4:15429572 C1QTNF7 0.27 5.8 0.3 1.55e-8 Obesity-related traits; LIHC cis rs736408 0.561 rs2276815 chr3:52853747 C/G cg11645453 chr3:52864694 ITIH4 0.29 7.67 0.38 1.87e-13 Bipolar disorder; LIHC cis rs77106637 0.860 rs75896506 chr11:72429579 G/A cg03713592 chr11:72463424 ARAP1 1.11 9.52 0.46 3.17e-19 Type 2 diabetes; LIHC cis rs3106136 0.546 rs2664881 chr4:95143484 A/G cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.32 -0.45 1.52e-18 Capecitabine sensitivity; LIHC cis rs6582630 0.519 rs4002440 chr12:38485012 A/G cg26384229 chr12:38710491 ALG10B 0.69 9.62 0.46 1.47e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs7772486 0.875 rs863820 chr6:146347402 C/T cg13319975 chr6:146136371 FBXO30 0.35 5.8 0.3 1.49e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg06634786 chr22:41940651 POLR3H -0.81 -9.24 -0.45 2.62e-18 Vitiligo; LIHC cis rs4820294 1.000 rs713835 chr22:38064650 C/T cg10587741 chr22:38071170 LGALS1 0.73 12.8 0.57 6.38e-31 Fat distribution (HIV); LIHC cis rs6684514 1.000 rs10908499 chr1:156279176 G/C cg16558208 chr1:156270281 VHLL 0.54 10.19 0.48 1.76e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7116495 0.786 rs2187496 chr11:71651961 G/C cg26138937 chr11:71823887 C11orf51 -0.62 -6.47 -0.33 3.44e-10 Severe influenza A (H1N1) infection; LIHC trans rs9951602 0.512 rs9958497 chr18:76655296 G/C cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs561341 1.000 rs576985 chr17:30323323 C/T cg00745463 chr17:30367425 LRRC37B -0.77 -5.73 -0.3 2.16e-8 Hip circumference adjusted for BMI; LIHC cis rs17428076 0.831 rs3821093 chr2:172694587 C/T cg13550731 chr2:172543902 DYNC1I2 0.37 6.01 0.31 4.89e-9 Myopia; LIHC cis rs9902453 0.791 rs57719820 chr17:28335088 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.73 -0.54 6.15e-27 Coffee consumption (cups per day); LIHC cis rs2108622 0.727 rs7251296 chr19:15983736 A/G cg13772218 chr19:15982569 NA 0.37 7.71 0.38 1.43e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs6430585 0.528 rs12464050 chr2:136663110 G/T cg25344623 chr2:136566232 LCT -0.38 -6.05 -0.31 3.71e-9 Corneal structure; LIHC cis rs2153535 0.623 rs2327055 chr6:8443145 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.77 0.54 4.25e-27 Motion sickness; LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg06873352 chr17:61820015 STRADA 0.75 13.62 0.59 4.83e-34 Prudent dietary pattern; LIHC cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg06238570 chr21:40685208 BRWD1 0.58 6.91 0.35 2.32e-11 Cognitive function; LIHC cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg06453172 chr10:134556979 INPP5A -0.65 -8.02 -0.4 1.75e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3096299 0.838 rs3102376 chr16:89402473 A/C cg08822215 chr16:89438651 ANKRD11 -0.46 -7.22 -0.36 3.44e-12 Multiple myeloma (IgH translocation); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14832358 chr2:45837811 SRBD1 0.4 6.4 0.33 5.1e-10 Cognitive function; LIHC cis rs6963495 0.818 rs73190186 chr7:105164368 G/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs11039798 0.764 rs11039929 chr11:48703289 A/G cg15704280 chr7:45808275 SEPT13 0.62 6.49 0.33 2.96e-10 Axial length; LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs8062405 1.000 rs4788095 chr16:28831359 T/C cg16576597 chr16:28551801 NUPR1 0.37 6.1 0.31 2.86e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg20295408 chr7:1910781 MAD1L1 -0.43 -6.32 -0.32 7.95e-10 Bipolar disorder and schizophrenia; LIHC cis rs1046896 0.594 rs4075209 chr17:80800027 G/T cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.49 0.38 6.1e-13 Glycated hemoglobin levels; LIHC cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg23758822 chr17:41437982 NA 0.94 17.9 0.7 5.08e-51 Menopause (age at onset); LIHC cis rs2404602 0.647 rs12440965 chr15:76958591 G/A cg03037974 chr15:76606532 NA -0.6 -10.0 -0.48 7.96e-21 Blood metabolite levels; LIHC cis rs1707322 1.000 rs1768807 chr1:46510570 A/G cg06784218 chr1:46089804 CCDC17 -0.36 -6.64 -0.34 1.25e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg05025164 chr4:1340916 KIAA1530 0.42 6.46 0.33 3.65e-10 Obesity-related traits; LIHC cis rs17253792 0.822 rs77415412 chr14:56154146 A/G cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC cis rs7520050 0.966 rs9429183 chr1:46524582 G/A cg03146154 chr1:46216737 IPP -0.36 -5.95 -0.31 6.46e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11671005 0.656 rs55652736 chr19:59007566 G/T cg25952890 chr19:58913133 NA 0.68 6.55 0.33 2.07e-10 Mean platelet volume; LIHC cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg12310025 chr6:25882481 NA 0.47 6.77 0.34 5.71e-11 Blood metabolite levels; LIHC cis rs6141600 0.540 rs964786 chr20:34688491 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.51 -0.33 2.66e-10 Height;Hip circumference; LIHC cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 6.55 0.33 2.12e-10 Schizophrenia; LIHC cis rs6831352 0.744 rs2602847 chr4:100025963 T/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Alcohol dependence; LIHC cis rs2816062 0.775 rs2816046 chr1:18893708 A/G cg18795169 chr1:18902165 NA -0.79 -17.48 -0.69 2.37e-49 Urate levels in lean individuals; LIHC trans rs7618501 0.521 rs2352984 chr3:49948728 T/C cg21659725 chr3:3221576 CRBN 0.56 8.25 0.41 3.46e-15 Intelligence (multi-trait analysis); LIHC cis rs9788682 1.000 rs7163730 chr15:78814681 A/G cg06917634 chr15:78832804 PSMA4 -0.49 -7.02 -0.36 1.18e-11 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs2153535 0.542 rs915353 chr6:8440370 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs477895 0.941 rs35692796 chr11:64110805 A/G cg04317338 chr11:64019027 PLCB3 0.84 7.6 0.38 2.82e-13 Mean platelet volume; LIHC cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg22800045 chr5:56110881 MAP3K1 0.66 8.48 0.42 6.66e-16 Initial pursuit acceleration; LIHC trans rs8073060 0.586 rs225288 chr17:33929291 G/A cg19694781 chr19:47549865 TMEM160 -1.25 -12.76 -0.57 9.07e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs59901009 0.954 rs7129531 chr11:10174447 A/G cg01453529 chr11:10209919 SBF2 0.29 5.75 0.3 2.02e-8 Hematocrit;Hemoglobin concentration; LIHC cis rs8062405 0.755 rs4149398 chr16:28608938 C/G cg16576597 chr16:28551801 NUPR1 0.47 7.13 0.36 6.11e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9296092 0.521 rs9461886 chr6:33526770 T/C cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs1215050 0.846 rs1839903 chr4:98791414 C/T cg05340658 chr4:99064831 C4orf37 0.45 6.19 0.32 1.73e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs769267 0.965 rs4808937 chr19:19398005 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.14e-9 Tonsillectomy; LIHC cis rs34779708 0.966 rs12784482 chr10:35446865 A/G cg04310649 chr10:35416472 CREM -0.42 -5.76 -0.3 1.91e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2073300 0.826 rs6137968 chr20:23449550 G/A cg12062639 chr20:23401060 NAPB 0.62 7.32 0.37 1.77e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs10506458 0.915 rs17687426 chr12:63397900 G/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.43 -0.49 2.73e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs10193935 0.901 rs59890734 chr2:42595662 G/A cg27598129 chr2:42591480 NA -0.8 -11.96 -0.54 9.15e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs35306767 0.715 rs1250891 chr10:1040159 G/C cg20503657 chr10:835505 NA 0.84 7.85 0.39 5.54e-14 Eosinophil percentage of granulocytes; LIHC cis rs801193 0.967 rs3800823 chr7:66147110 C/A cg11764359 chr7:65958608 NA -0.69 -10.07 -0.48 4.77e-21 Aortic root size; LIHC cis rs4631830 0.900 rs10763546 chr10:51536399 C/G cg20129853 chr10:51489980 NA -0.39 -8.59 -0.42 3.06e-16 Prostate-specific antigen levels; LIHC cis rs9309711 0.772 rs9309715 chr2:3492318 C/G cg10845886 chr2:3471009 TTC15 0.58 10.58 0.5 8.23e-23 Neurofibrillary tangles; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg24693881 chr1:107596107 NA -0.52 -9.33 -0.45 1.33e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9399135 0.933 rs28384512 chr6:135376232 C/T cg22676075 chr6:135203613 NA 0.4 6.44 0.33 4.09e-10 Red blood cell count; LIHC cis rs7208859 0.673 rs216435 chr17:28922737 G/T cg14067834 chr17:29058358 SUZ12P 0.64 6.73 0.34 7.16e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs10078 0.510 rs2278248 chr5:469570 G/T cg24955955 chr5:415729 AHRR 0.52 10.27 0.49 9.96e-22 Fat distribution (HIV); LIHC cis rs1728785 0.901 rs11075688 chr16:68655924 A/G cg02972257 chr16:68554789 NA 0.54 6.36 0.33 6.45e-10 Ulcerative colitis; LIHC cis rs919433 0.680 rs6710530 chr2:198277551 G/A cg10820045 chr2:198174542 NA 0.55 8.96 0.44 2.12e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2153535 0.542 rs9393012 chr6:8439809 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.3e-16 Motion sickness; LIHC cis rs909002 0.789 rs56074668 chr1:32123801 T/C cg13919466 chr1:32135498 COL16A1 -0.34 -6.23 -0.32 1.37e-9 Intelligence (multi-trait analysis); LIHC cis rs9517313 0.592 rs61969458 chr13:99177633 A/G cg20487152 chr13:99095054 FARP1 -0.38 -6.35 -0.32 6.74e-10 Neuroticism; LIHC cis rs11792861 0.816 rs2275637 chr9:111696043 C/G cg05043794 chr9:111880884 C9orf5 -0.29 -6.79 -0.34 4.98e-11 Menarche (age at onset); LIHC cis rs6546550 0.901 rs7598283 chr2:70128717 A/G cg02498382 chr2:70120550 SNRNP27 -0.44 -7.61 -0.38 2.69e-13 Prevalent atrial fibrillation; LIHC cis rs35306767 0.903 rs35637113 chr10:874149 G/C cg20503657 chr10:835505 NA 1.09 12.06 0.55 3.66e-28 Eosinophil percentage of granulocytes; LIHC cis rs11212260 0.655 rs7925025 chr11:107283058 G/A cg25435332 chr11:107328525 CWF19L2 0.8 8.71 0.43 1.36e-16 IgG glycosylation; LIHC cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg15691649 chr6:25882328 NA -0.6 -7.75 -0.39 1.04e-13 Intelligence (multi-trait analysis); LIHC cis rs847649 0.731 rs10808120 chr7:102672234 A/G cg18108683 chr7:102477205 FBXL13 -0.39 -5.85 -0.3 1.18e-8 Morning vs. evening chronotype; LIHC cis rs7429990 0.864 rs6777081 chr3:48155569 T/C cg11946769 chr3:48343235 NME6 -0.49 -6.23 -0.32 1.37e-9 Educational attainment (years of education); LIHC trans rs60843830 1.000 rs11553746 chr2:272203 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.56 0.46 2.46e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2832191 0.755 rs2832192 chr21:30491173 G/T cg24692254 chr21:30365293 RNF160 -0.51 -8.87 -0.43 4.1e-17 Dental caries; LIHC cis rs2806561 0.929 rs10917357 chr1:23535161 C/T cg19743168 chr1:23544995 NA 0.43 7.96 0.4 2.61e-14 Height; LIHC cis rs853679 0.513 rs13437444 chr6:28070998 C/T cg16479474 chr6:28041457 NA 0.47 6.06 0.31 3.55e-9 Depression; LIHC cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.47 -6.72 -0.34 7.77e-11 Gut microbiome composition (summer); LIHC cis rs3741151 0.881 rs79623427 chr11:73094896 C/T cg17517138 chr11:73019481 ARHGEF17 0.86 6.15 0.32 2.18e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs13191362 0.935 rs35100164 chr6:162963003 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.7 5.98 0.31 5.77e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6952808 0.929 rs2280550 chr7:1976556 G/A cg21782813 chr7:2030301 MAD1L1 0.47 8.1 0.4 9.64e-15 Bipolar disorder and schizophrenia; LIHC cis rs7223966 0.960 rs2319990 chr17:61705397 T/C cg05941027 chr17:61774174 LIMD2 0.32 6.44 0.33 4.02e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs8180040 0.726 rs11130112 chr3:47024495 G/T cg27129171 chr3:47204927 SETD2 0.6 10.28 0.49 9.17e-22 Colorectal cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14280964 chr1:37940281 ZC3H12A -0.53 -6.64 -0.34 1.23e-10 Systolic blood pressure; LIHC cis rs9549328 0.756 rs2993291 chr13:113653846 C/T cg18289306 chr13:113640169 MCF2L 0.46 7.27 0.37 2.45e-12 Systolic blood pressure; LIHC cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg23758822 chr17:41437982 NA 0.95 18.06 0.7 1.16e-51 Menopause (age at onset); LIHC cis rs7945705 0.935 rs2568062 chr11:8887945 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -9.46 -0.46 5.01e-19 Hemoglobin concentration; LIHC trans rs2727020 0.521 rs7101761 chr11:49598178 G/A cg03929089 chr4:120376271 NA -0.67 -9.61 -0.46 1.66e-19 Coronary artery disease; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs9296092 0.560 rs7765263 chr6:33525559 A/G cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs12971120 1.000 rs3829640 chr18:72174980 A/G cg25817165 chr18:72167213 CNDP2 -0.71 -12.77 -0.57 8.34e-31 Refractive error; LIHC cis rs9318086 0.712 rs66683041 chr13:24442090 T/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.73 14.95 0.63 3.09e-39 Myopia (pathological); LIHC cis rs12477438 0.501 rs2632260 chr2:99771590 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg00341915 chr10:119806516 CASC2;RAB11FIP2 0.55 6.57 0.33 1.84e-10 Glycated hemoglobin levels; LIHC cis rs7707921 0.881 rs112413913 chr5:81359709 A/G cg15871215 chr5:81402204 ATG10 -0.62 -5.98 -0.31 5.56e-9 Breast cancer; LIHC cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg03264133 chr6:25882463 NA 0.61 7.37 0.37 1.3e-12 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg18538332 chr22:24372958 LOC391322 -0.73 -11.2 -0.52 5.03e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6088590 1.000 rs2378256 chr20:33292127 G/C cg08999081 chr20:33150536 PIGU 0.4 6.15 0.32 2.22e-9 Coronary artery disease; LIHC cis rs2404602 0.591 rs11635162 chr15:76951105 C/T cg23625390 chr15:77176239 SCAPER -0.47 -7.43 -0.37 8.85e-13 Blood metabolite levels; LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg13409248 chr3:40428643 ENTPD3 0.49 8.22 0.41 4.34e-15 Renal cell carcinoma; LIHC cis rs2274273 0.870 rs8018110 chr14:55641714 C/T cg01864836 chr14:55583639 NA -0.42 -8.17 -0.4 6.16e-15 Protein biomarker; LIHC cis rs2066819 1.000 rs773664 chr12:56702176 C/T cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Psoriasis vulgaris; LIHC trans rs11098499 0.908 rs12504149 chr4:120318577 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.72 0.47 7.01e-20 Corneal astigmatism; LIHC cis rs7726839 0.540 rs72705102 chr5:659437 T/C cg09021430 chr5:549028 NA -0.43 -8.55 -0.42 4.21e-16 Obesity-related traits; LIHC cis rs876084 0.505 rs10955953 chr8:121106381 C/T cg06265175 chr8:121136014 COL14A1 -0.49 -7.9 -0.39 3.74e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg18279126 chr7:2041391 MAD1L1 0.37 6.12 0.31 2.62e-9 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs3938660 chr6:8443335 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs11676348 0.818 rs6436033 chr2:218983763 A/G cg00012203 chr2:219082015 ARPC2 -0.55 -7.56 -0.38 3.83e-13 Ulcerative colitis; LIHC cis rs8084351 0.539 rs7506784 chr18:50576221 A/T cg24270629 chr18:50823537 DCC 0.41 6.34 0.32 7.31e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2404602 0.647 rs7165053 chr15:76978918 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.23 -0.45 2.8e-18 Blood metabolite levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06651054 chr15:83680015 C15orf40 -0.58 -7.23 -0.36 3.23e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3862260 1.000 rs3862260 chr1:120160789 G/A cg16322792 chr1:120165303 ZNF697 0.46 8.45 0.42 8.77e-16 Systemic lupus erythematosus; LIHC cis rs2274273 0.934 rs8021940 chr14:55719715 G/A cg01864836 chr14:55583639 NA -0.43 -8.11 -0.4 9.18e-15 Protein biomarker; LIHC cis rs1371867 0.839 rs1660313 chr8:101332712 G/A cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC trans rs7618501 1.000 rs11130218 chr3:49752372 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs743757 1.000 rs2236973 chr3:50474284 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.5 7.89 0.39 4e-14 Diastolic blood pressure; LIHC cis rs6466055 0.748 rs10281422 chr7:104844519 G/A cg04380332 chr7:105027541 SRPK2 -0.36 -6.74 -0.34 6.5500000000000006e-11 Schizophrenia; LIHC cis rs1371867 0.817 rs1788185 chr8:101335529 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC cis rs7107174 1.000 rs7112234 chr11:78102470 G/A cg02023728 chr11:77925099 USP35 0.39 7.38 0.37 1.22e-12 Testicular germ cell tumor; LIHC cis rs8072100 0.676 rs9905308 chr17:45409386 T/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -6.12 -0.31 2.55e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg13271783 chr10:134563150 INPP5A -0.51 -6.66 -0.34 1.07e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg09297361 chr15:64444268 SNX22 -0.38 -6.12 -0.31 2.56e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7772486 0.624 rs6930154 chr6:146025662 C/T cg23711669 chr6:146136114 FBXO30 -0.69 -12.81 -0.57 5.98e-31 Lobe attachment (rater-scored or self-reported); LIHC trans rs79243044 0.786 rs16932549 chr11:5560909 C/T cg07237590 chr20:62526788 DNAJC5 -0.51 -6.14 -0.32 2.33e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs57590327 0.508 rs10511101 chr3:81950302 A/C cg07356753 chr3:81810745 GBE1 -0.54 -8.41 -0.41 1.13e-15 Extraversion; LIHC cis rs7267979 0.565 rs6076364 chr20:25556801 T/C cg24626310 chr20:25276739 ABHD12;PYGB -0.44 -6.02 -0.31 4.47e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs1904096 0.506 rs4693378 chr4:95168552 A/T cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.24 -0.45 2.76e-18 Type 2 diabetes; LIHC cis rs10504229 0.906 rs56130194 chr8:58197061 C/A cg02290350 chr8:58132656 NA 0.38 7.37 0.37 1.28e-12 Developmental language disorder (linguistic errors); LIHC trans rs7246657 0.943 rs10415024 chr19:37814724 A/G cg10208301 chr11:6592745 DNHD1 0.45 6.13 0.31 2.41e-9 Coronary artery calcification; LIHC cis rs12477438 0.798 rs1453561 chr2:99613924 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.82 -10.42 -0.49 3.02e-22 Chronic sinus infection; LIHC cis rs4819052 0.851 rs2236445 chr21:46678453 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 11.09 0.51 1.31e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3106136 0.903 rs35361491 chr4:95202492 G/A cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.0 -0.4 1.89e-14 Capecitabine sensitivity; LIHC cis rs4742903 0.935 rs7875929 chr9:106931408 A/G cg14250997 chr9:106856677 SMC2 0.36 6.08 0.31 3.2e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1552244 0.554 rs2272121 chr3:10047680 A/G cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs722599 0.748 rs929579 chr14:75330697 C/T cg08847533 chr14:75593920 NEK9 -0.53 -8.27 -0.41 2.97e-15 IgG glycosylation; LIHC cis rs7542091 0.739 rs10863793 chr1:210037420 G/A cg23283495 chr1:209979779 IRF6 0.35 5.94 0.31 6.91e-9 Monobrow; LIHC cis rs6450176 0.633 rs391448 chr5:53332323 A/G ch.5.1024479R chr5:53302184 ARL15 -0.76 -13.72 -0.6 1.87e-34 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs798554 0.759 rs798495 chr7:2797267 T/C cg13628971 chr7:2884303 GNA12 0.53 7.78 0.39 8.83e-14 Height; LIHC cis rs988712 0.705 rs4923460 chr11:27656789 A/C cg18117895 chr11:27722066 BDNF -0.47 -6.41 -0.33 4.84e-10 Obesity; LIHC cis rs9549367 0.789 rs9549695 chr13:113874814 A/G cg00898013 chr13:113819073 PROZ 0.41 7.05 0.36 1.02e-11 Platelet distribution width; LIHC trans rs3749237 0.964 rs7431078 chr3:49808190 G/A cg21659725 chr3:3221576 CRBN 0.8 12.52 0.56 7.49e-30 Resting heart rate; LIHC cis rs2204008 0.546 rs11519978 chr12:37998170 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs12477438 0.559 rs6733285 chr2:99725575 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs2204008 0.837 rs2127955 chr12:37969194 A/G cg26384229 chr12:38710491 ALG10B 0.47 6.63 0.34 1.3100000000000001e-10 Bladder cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00261534 chr10:3826854 KLF6 0.42 6.26 0.32 1.17e-9 Pancreatic cancer; LIHC cis rs847649 0.699 rs10271157 chr7:102527591 A/G cg18108683 chr7:102477205 FBXL13 -0.48 -7.41 -0.37 1.03e-12 Morning vs. evening chronotype; LIHC cis rs6748734 0.948 rs4471886 chr2:241838622 T/C cg09990169 chr2:241835740 C2orf54 -0.71 -11.49 -0.53 4.78e-26 Urinary metabolites; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03759077 chr2:153575599 ARL6IP6 0.38 6.05 0.31 3.86e-9 Cognitive function; LIHC cis rs13401104 0.796 rs1466206 chr2:237121221 G/C cg19324714 chr2:237145437 ASB18 0.37 5.85 0.3 1.13e-8 Educational attainment; LIHC cis rs2279817 0.780 rs71644065 chr1:18001669 C/T cg21791023 chr1:18019539 ARHGEF10L -0.69 -7.93 -0.39 3.1e-14 Neuroticism; LIHC cis rs1552244 0.882 rs7633769 chr3:10020622 C/T cg00149659 chr3:10157352 C3orf10 0.49 5.85 0.3 1.12e-8 Alzheimer's disease; LIHC cis rs7474896 0.583 rs4934898 chr10:37990395 G/C cg25427524 chr10:38739819 LOC399744 -0.49 -7.22 -0.36 3.35e-12 Obesity (extreme); LIHC cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.75e-9 Menopause (age at onset); LIHC cis rs7572733 0.534 rs4369854 chr2:198800630 T/C cg10820045 chr2:198174542 NA 0.48 7.47 0.37 6.93e-13 Dermatomyositis; LIHC trans rs9929218 0.954 rs12599393 chr16:68829021 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.33 -0.41 1.95e-15 Colorectal cancer; LIHC cis rs9486719 0.947 rs2499801 chr6:96854594 G/A cg06623918 chr6:96969491 KIAA0776 0.69 6.69 0.34 8.89e-11 Migraine;Coronary artery disease; LIHC cis rs7772486 0.790 rs6570724 chr6:146151283 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.83 0.3 1.3e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg11644478 chr21:40555479 PSMG1 0.84 10.9 0.51 6.12e-24 Cognitive function; LIHC cis rs826838 1.000 rs7315028 chr12:38710523 G/A cg13010199 chr12:38710504 ALG10B 0.64 7.89 0.39 4.03e-14 Heart rate; LIHC cis rs17270561 0.562 rs74293932 chr6:26014811 C/A cg16482183 chr6:26056742 HIST1H1C 0.85 11.13 0.52 9.03e-25 Iron status biomarkers; LIHC cis rs3020736 0.500 rs764481 chr22:42518426 G/A cg04733989 chr22:42467013 NAGA -0.64 -9.18 -0.44 4.09e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs4474465 1.000 rs10751290 chr11:78192707 G/A cg27205649 chr11:78285834 NARS2 -0.4 -6.23 -0.32 1.38e-9 Alzheimer's disease (survival time); LIHC cis rs2153535 0.541 rs9328471 chr6:8468842 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs10504229 0.593 rs58647001 chr8:58025132 G/A cg02290350 chr8:58132656 NA 0.3 6.71 0.34 8.26e-11 Developmental language disorder (linguistic errors); LIHC cis rs853679 0.517 rs3757185 chr6:28107776 T/A cg23485639 chr6:28045615 ZNF165 0.44 5.74 0.3 2.08e-8 Depression; LIHC cis rs9814567 1.000 rs6769885 chr3:134286913 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8027181 0.839 rs7176235 chr15:72999104 A/G cg25632853 chr15:73088954 NA 0.36 5.96 0.31 6.41e-9 Triglyceride levels; LIHC cis rs11039131 0.629 rs67871383 chr11:47335838 T/C cg20135002 chr11:47629003 NA -0.38 -6.03 -0.31 4.19e-9 Schizophrenia; LIHC cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.1 16.91 0.67 4.69e-47 Gut microbiome composition (summer); LIHC cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg22963979 chr7:1858916 MAD1L1 -0.37 -5.79 -0.3 1.58e-8 Bipolar disorder and schizophrenia; LIHC cis rs10464366 0.544 rs4723824 chr7:39153698 T/C cg10621924 chr7:39171070 POU6F2 0.42 6.43 0.33 4.38e-10 IgG glycosylation; LIHC cis rs17106184 1.000 rs72902722 chr1:51223002 T/C cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs763121 0.853 rs2076028 chr22:39150450 G/A cg06544989 chr22:39130855 UNC84B 0.37 5.83 0.3 1.27e-8 Menopause (age at onset); LIHC cis rs9948 0.655 rs2314399 chr2:97442390 G/A cg01990225 chr2:97406019 LMAN2L -0.82 -6.4 -0.33 5.23e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg16434002 chr17:42200994 HDAC5 0.47 6.97 0.35 1.6e-11 Total body bone mineral density; LIHC cis rs116095464 0.558 rs6874745 chr5:264527 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs5769707 0.967 rs17182154 chr22:49990470 A/G cg07959070 chr22:50026188 C22orf34 -0.3 -7.69 -0.38 1.58e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6500602 0.702 rs6500606 chr16:4502514 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.5 -7.94 -0.39 2.97e-14 Schizophrenia; LIHC cis rs9300255 0.602 rs2851435 chr12:123712416 G/A cg00376283 chr12:123451042 ABCB9 0.6 5.91 0.3 8.48e-9 Neutrophil percentage of white cells; LIHC cis rs10504229 1.000 rs59797486 chr8:58174435 T/C cg02290350 chr8:58132656 NA 0.41 8.54 0.42 4.62e-16 Developmental language disorder (linguistic errors); LIHC cis rs950776 0.518 rs12906846 chr15:78825295 G/A cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09610735 chr10:22609918 BMI1 0.44 6.11 0.31 2.72e-9 Pancreatic cancer; LIHC cis rs2115630 0.902 rs8023276 chr15:85219638 C/T cg11189052 chr15:85197271 WDR73 -0.43 -6.35 -0.32 7.03e-10 P wave terminal force; LIHC cis rs7223966 1.000 rs6504168 chr17:61697469 G/T cg05941027 chr17:61774174 LIMD2 0.34 7.13 0.36 5.91e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1799949 0.965 rs4239149 chr17:41328095 A/G cg05368731 chr17:41323189 NBR1 -0.69 -11.4 -0.52 9.85e-26 Menopause (age at onset); LIHC cis rs15676 0.947 rs1572912 chr9:131565554 T/C cg00228799 chr9:131580591 ENDOG -0.47 -7.1 -0.36 7.05e-12 Blood metabolite levels; LIHC cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg12386194 chr3:101231763 SENP7 0.46 6.76 0.34 6.11e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs3106136 0.967 rs11097411 chr4:95222626 C/T cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.01 -0.4 1.87e-14 Capecitabine sensitivity; LIHC cis rs8141529 0.732 rs6005872 chr22:29172898 T/G cg02153584 chr22:29168773 CCDC117 0.56 9.15 0.44 5.27e-18 Lymphocyte counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07372840 chr5:180296196 NA 0.48 6.53 0.33 2.32e-10 Pancreatic cancer; LIHC cis rs11608355 0.545 rs7139106 chr12:109908640 G/A cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs2380220 1.000 rs2380222 chr6:95975395 C/T cg15832292 chr6:96025679 MANEA 0.63 6.98 0.35 1.58e-11 Behavioural disinhibition (generation interaction); LIHC cis rs3008870 1.000 rs2985821 chr1:67403787 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs644799 0.931 rs496305 chr11:95567035 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.76 0.67 1.96e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11792861 0.781 rs17729408 chr9:111740860 A/G cg05043794 chr9:111880884 C9orf5 0.29 6.88 0.35 2.83e-11 Menarche (age at onset); LIHC cis rs2075371 0.863 rs9641966 chr7:133961205 G/A cg11752832 chr7:134001865 SLC35B4 0.46 5.82 0.3 1.37e-8 Mean platelet volume; LIHC cis rs700651 0.757 rs6748683 chr2:198878008 T/A cg03934865 chr2:198174659 NA 0.46 6.61 0.34 1.5e-10 Intracranial aneurysm; LIHC cis rs2153535 0.580 rs6941771 chr6:8494452 T/G cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs34779708 0.966 rs12761675 chr10:35438337 C/T cg04310649 chr10:35416472 CREM 0.42 5.71 0.3 2.45e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs57590327 0.679 rs35259664 chr3:81586742 C/G cg07356753 chr3:81810745 GBE1 -0.47 -6.49 -0.33 2.97e-10 Extraversion; LIHC cis rs72829446 0.530 rs4796422 chr17:7380004 T/C cg02795151 chr17:7402630 POLR2A 0.54 5.85 0.3 1.13e-8 Androgen levels; LIHC cis rs7715806 0.500 rs17649266 chr5:75001252 C/T cg19683494 chr5:74908142 NA -0.7 -8.24 -0.41 3.82e-15 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7772486 0.875 rs932522 chr6:146374026 A/G cg05347473 chr6:146136440 FBXO30 -0.39 -6.4 -0.33 5.15e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.29 -0.45 1.85e-18 Bipolar disorder; LIHC cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg04083430 chr16:4736063 MGRN1 -0.41 -5.81 -0.3 1.43e-8 Schizophrenia; LIHC cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg12310025 chr6:25882481 NA 0.56 7.63 0.38 2.39e-13 Blood metabolite levels; LIHC cis rs10508774 0.866 rs10827057 chr10:32731375 G/T cg01819863 chr10:32635814 EPC1 0.66 6.18 0.32 1.84e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17106184 0.892 rs57400675 chr1:51068657 C/T cg07174182 chr1:51127561 FAF1 -0.61 -6.23 -0.32 1.41e-9 Type 2 diabetes; LIHC cis rs4906332 1.000 rs34347076 chr14:103955069 G/A cg04998671 chr14:104000505 TRMT61A -0.46 -6.26 -0.32 1.17e-9 Coronary artery disease; LIHC trans rs5756813 0.754 rs8136757 chr22:38185971 A/G cg19894588 chr14:64061835 NA -0.65 -9.18 -0.44 4.16e-18 Optic cup area;Vertical cup-disc ratio; LIHC cis rs250677 0.522 rs1432798 chr5:148383345 C/G cg12140854 chr5:148520817 ABLIM3 -0.44 -6.0 -0.31 4.93e-9 Breast cancer; LIHC cis rs28595532 0.623 rs71608363 chr4:119227259 T/C cg21605333 chr4:119757512 SEC24D 0.8 6.87 0.35 3.14e-11 Cannabis dependence symptom count; LIHC cis rs992157 0.798 rs4996257 chr2:219162836 C/T cg00012203 chr2:219082015 ARPC2 0.85 13.98 0.6 1.84e-35 Colorectal cancer; LIHC cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg21724239 chr8:58056113 NA 0.62 7.46 0.37 7.14e-13 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.623 rs7220289 chr17:29103762 G/T cg14067834 chr17:29058358 SUZ12P 0.7 6.88 0.35 2.88e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12824058 0.831 rs55726136 chr12:130810312 G/A cg26677194 chr12:130822605 PIWIL1 0.52 7.36 0.37 1.36e-12 Menopause (age at onset); LIHC cis rs10792665 0.614 rs4944423 chr11:82774606 T/C cg24227371 chr11:82718527 RAB30 -0.39 -9.5 -0.46 3.76e-19 Obesity-related traits; LIHC trans rs7615952 0.932 rs13325495 chr3:125637416 T/G cg07211511 chr3:129823064 LOC729375 -0.86 -10.46 -0.49 2.05e-22 Blood pressure (smoking interaction); LIHC cis rs2108622 0.701 rs3093209 chr19:15988420 G/C cg13772218 chr19:15982569 NA 0.36 7.35 0.37 1.49e-12 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs9612 0.950 rs60649310 chr19:44269241 A/G cg08581076 chr19:44259116 C19orf61 0.61 7.34 0.37 1.57e-12 Exhaled nitric oxide output; LIHC cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg04944784 chr2:26401820 FAM59B -0.71 -8.87 -0.43 4.14e-17 Gut microbiome composition (summer); LIHC cis rs67460515 0.892 rs34896809 chr3:161059804 C/T cg03342759 chr3:160939853 NMD3 -0.58 -8.59 -0.42 3.2e-16 Parkinson's disease; LIHC trans rs2122469 0.655 rs74661770 chr8:20581855 G/T cg20211604 chr17:11632341 DNAH9 0.48 6.08 0.31 3.28e-9 Serum tamsulosin hydrochloride concentration; LIHC cis rs208520 0.690 rs851468 chr6:66825875 G/A cg07460842 chr6:66804631 NA -0.76 -8.31 -0.41 2.27e-15 Exhaled nitric oxide output; LIHC cis rs8072100 0.967 rs8075411 chr17:45676760 C/T cg08085267 chr17:45401833 C17orf57 0.41 6.11 0.31 2.7e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4589502 0.800 rs12595796 chr15:67202599 A/G cg12317470 chr15:67143691 NA -0.6 -7.33 -0.37 1.66e-12 Lung cancer (smoking interaction); LIHC trans rs11098499 0.775 rs10021601 chr4:120282563 G/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs9818758 0.607 rs11552724 chr3:49156473 C/G cg00383909 chr3:49044727 WDR6 0.84 7.15 0.36 5.14e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11229555 0.609 rs11229434 chr11:58185501 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7927771 0.965 rs1064608 chr11:47640429 G/C cg20307385 chr11:47447363 PSMC3 -0.44 -5.78 -0.3 1.67e-8 Subjective well-being; LIHC cis rs4925386 0.808 rs1741634 chr20:60925979 A/C cg06026331 chr20:60912101 LAMA5 -0.5 -8.68 -0.42 1.7e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs1878931 0.624 rs28089 chr16:3446937 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -7.9 -0.39 3.97e-14 Body mass index (adult); LIHC cis rs11676855 0.927 rs4663180 chr2:235921195 A/G cg02447239 chr2:235936137 SH3BP4 -0.35 -6.05 -0.31 3.89e-9 Dialysis-related mortality; LIHC cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg14004847 chr7:1930337 MAD1L1 -0.64 -9.93 -0.47 1.35e-20 Bipolar disorder and schizophrenia; LIHC trans rs916888 0.687 rs199456 chr17:44797919 C/T cg22968622 chr17:43663579 NA 1.19 13.18 0.58 2.28e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9649465 0.967 rs12537989 chr7:123308195 A/G cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.58e-14 Migraine; LIHC cis rs9457247 0.765 rs6904946 chr6:167433948 C/T cg07741184 chr6:167504864 NA -0.34 -8.07 -0.4 1.23e-14 Crohn's disease; LIHC cis rs6076065 0.748 rs2253834 chr20:23387816 C/T cg11657817 chr20:23433608 CST11 -0.27 -5.72 -0.3 2.29e-8 Facial morphology (factor 15, philtrum width); LIHC cis rs916888 0.821 rs199506 chr17:44859031 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.83 -0.35 3.8e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2235642 0.507 rs2235645 chr16:1597924 C/T cg03034668 chr16:1723424 CRAMP1L -0.41 -6.44 -0.33 3.95e-10 Coronary artery disease; LIHC cis rs17401966 0.838 rs946501 chr1:10309580 C/G cg19773385 chr1:10388646 KIF1B -0.4 -7.45 -0.37 7.59e-13 Hepatocellular carcinoma; LIHC cis rs2108225 0.900 rs4518594 chr7:107451060 G/C cg18560240 chr7:107437656 SLC26A3 -0.38 -5.76 -0.3 1.84e-8 Ulcerative colitis; LIHC cis rs7131987 0.650 rs10843377 chr12:29437053 C/G cg16970926 chr12:29381810 FAR2 -0.32 -6.53 -0.33 2.44e-10 QT interval; LIHC cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg12463550 chr7:65579703 CRCP 0.68 7.05 0.36 9.9e-12 Diabetic kidney disease; LIHC cis rs74417235 0.684 rs13179358 chr5:154059746 C/A cg08893839 chr5:154027129 NA 0.49 6.74 0.34 6.64e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg07636037 chr3:49044803 WDR6 0.89 15.57 0.64 1.06e-41 Parkinson's disease; LIHC cis rs3008870 1.000 rs2985794 chr1:67425311 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.29 0.66 1.46e-44 Lymphocyte percentage of white cells; LIHC cis rs6912958 0.781 rs6454632 chr6:88231824 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.83 -0.39 6.25e-14 Monocyte percentage of white cells; LIHC cis rs360798 0.532 rs2421816 chr2:63075033 C/A cg17519650 chr2:63277830 OTX1 0.45 7.03 0.36 1.11e-11 Coronary artery disease; LIHC cis rs1008375 1.000 rs28552744 chr4:17620165 A/G cg02297831 chr4:17616191 MED28 0.49 7.57 0.38 3.54e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26120584 chr12:50795366 LARP4 0.47 6.92 0.35 2.18e-11 Cognitive function; LIHC cis rs2204008 0.677 rs1581356 chr12:38391467 T/C cg26384229 chr12:38710491 ALG10B 0.55 7.43 0.37 8.94e-13 Bladder cancer; LIHC trans rs875971 0.660 rs801217 chr7:66010577 C/T cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC cis rs3862030 0.810 rs5870 chr10:104239100 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -7.74 -0.39 1.14e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC trans rs8002861 0.935 rs9533672 chr13:44451180 C/T cg17145862 chr1:211918768 LPGAT1 0.58 10.73 0.5 2.47e-23 Leprosy; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.95 21.0 0.75 1.71e-63 Prudent dietary pattern; LIHC cis rs875971 0.545 rs10950036 chr7:65818228 G/T cg11764359 chr7:65958608 NA 0.57 8.05 0.4 1.42e-14 Aortic root size; LIHC cis rs6951245 0.507 rs11976805 chr7:1138716 C/T cg23978390 chr7:1156363 C7orf50 0.63 7.98 0.4 2.24e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs709400 0.663 rs17617941 chr14:103953032 T/C cg26031613 chr14:104095156 KLC1 0.75 9.28 0.45 1.99e-18 Body mass index; LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg07725925 chr16:89976287 TCF25 0.45 6.16 0.32 2e-9 Skin colour saturation; LIHC cis rs3981351 0.797 rs28411397 chr10:115439530 G/C cg24846397 chr10:115438155 CASP7 -0.45 -6.96 -0.35 1.78e-11 Obesity-related traits; LIHC cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg22168489 chr12:122356033 WDR66 0.48 7.89 0.39 4.12e-14 Mean corpuscular volume; LIHC cis rs17102423 0.594 rs10151162 chr14:65566695 T/C cg16583315 chr14:65563665 MAX -0.4 -8.2 -0.41 5.07e-15 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08833169 chr11:810149 RPLP2 -0.4 -6.43 -0.33 4.35e-10 Pancreatic cancer; LIHC cis rs7607369 0.648 rs17470271 chr2:219651995 A/T cg02176678 chr2:219576539 TTLL4 0.43 5.8 0.3 1.49e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7223966 1.000 rs2665826 chr17:61944924 A/G cg05941027 chr17:61774174 LIMD2 0.31 6.5 0.33 2.84e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg03264133 chr6:25882463 NA 0.59 8.08 0.4 1.11e-14 Blood metabolite levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg07495314 chr13:27845355 RASL11A -0.52 -6.04 -0.31 4.13e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs600806 0.888 rs3853498 chr1:109860144 T/C cg16275483 chr1:110013120 SYPL2 -0.5 -6.22 -0.32 1.44e-9 Intelligence (multi-trait analysis); LIHC cis rs5997397 0.967 rs5762777 chr22:29150044 T/C cg02153584 chr22:29168773 CCDC117 0.47 7.2 0.36 3.9e-12 Red cell distribution width; LIHC cis rs142958719 1 rs142958719 chr5:131232959 G/A cg06307176 chr5:131281290 NA -0.41 -5.83 -0.3 1.28e-8 Alzheimer's disease in APOE e4- carriers; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25631650 chr19:633157 POLRMT 0.44 6.82 0.35 4.14e-11 Cognitive function; LIHC cis rs9513627 1.000 rs7327068 chr13:100126965 A/G cg25919922 chr13:100150906 NA -0.77 -6.94 -0.35 2.01e-11 Obesity-related traits; LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg02951883 chr7:2050386 MAD1L1 -0.77 -13.43 -0.59 2.51e-33 Bipolar disorder and schizophrenia; LIHC cis rs77633900 0.772 rs157789 chr15:76805703 T/A cg21673338 chr15:77095150 SCAPER -0.53 -6.09 -0.31 3.11e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs244293 0.695 rs9303360 chr17:53001456 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.52 -7.81 -0.39 6.92e-14 Menarche (age at onset); LIHC cis rs10916814 0.610 rs4655222 chr1:20901418 C/T cg24502330 chr1:20914028 CDA -0.3 -6.73 -0.34 7.16e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6088590 0.965 rs6087639 chr20:33443866 G/A cg06115741 chr20:33292138 TP53INP2 0.59 7.9 0.39 3.83e-14 Coronary artery disease; LIHC cis rs1348850 0.914 rs12693120 chr2:178283288 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.84 13.31 0.58 7.13e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs9858542 1.000 rs2172252 chr3:49678307 A/T cg21659725 chr3:3221576 CRBN -0.57 -6.41 -0.33 4.91e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg03517284 chr6:25882590 NA -1.16 -18.36 -0.7 7.13e-53 Urate levels; LIHC cis rs2072499 0.966 rs2244144 chr1:156184598 G/A cg24450063 chr1:156163899 SLC25A44 1.05 17.2 0.68 3.19e-48 Testicular germ cell tumor; LIHC trans rs1814175 0.645 rs1721997 chr11:49916653 T/C cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs7666738 0.830 rs9884501 chr4:98893721 A/C cg05340658 chr4:99064831 C4orf37 0.66 11.88 0.54 1.7e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs2758596 0.850 rs2842879 chr1:156163695 G/T cg25208724 chr1:156163844 SLC25A44 0.79 8.79 0.43 7.49e-17 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg23205692 chr1:25664452 TMEM50A 0.38 6.15 0.32 2.1e-9 Erythrocyte sedimentation rate; LIHC cis rs3806843 0.741 rs4912597 chr5:140106857 C/G cg19875535 chr5:140030758 IK -0.41 -6.7 -0.34 8.83e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs644799 0.526 rs693792 chr11:95622200 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.56 7.87 0.39 4.84e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7408868 1.000 rs2074622 chr19:15277620 G/C cg14696996 chr19:15285081 NOTCH3 0.53 7.11 0.36 6.93e-12 Pulse pressure; LIHC cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg03264133 chr6:25882463 NA -0.61 -8.65 -0.42 2.08e-16 Blood metabolite levels; LIHC cis rs801193 0.569 rs6978178 chr7:66123084 G/A cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs9814567 0.752 rs7649910 chr3:134241310 A/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs201287033 1 rs201287033 chr7:150823227 TCCG/T cg10920230 chr7:150757210 SLC4A2 -0.73 -5.92 -0.31 7.65e-9 Eyebrow thickness; LIHC cis rs1564271 0.528 rs2209350 chr10:26987779 A/G cg13837822 chr10:26931731 LOC731789 0.38 7.42 0.37 9.28e-13 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC trans rs10506458 0.688 rs60936040 chr12:63416461 G/A cg22491629 chr6:157744540 C6orf35 -0.55 -10.21 -0.48 1.56e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs11711311 1.000 rs13061150 chr3:113506734 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.23 -0.36 3.12e-12 IgG glycosylation; LIHC cis rs2273156 1.000 rs7153068 chr14:35459481 A/T cg16230307 chr14:35515116 FAM177A1 -0.41 -6.04 -0.31 3.96e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs3782089 1.000 rs11602375 chr11:65296540 C/T cg00206168 chr11:65308501 LTBP3 1.09 7.68 0.38 1.71e-13 Height; LIHC cis rs4268898 0.931 rs60716082 chr2:24526265 T/A cg06627628 chr2:24431161 ITSN2 -0.55 -7.95 -0.4 2.69e-14 Asthma; LIHC cis rs7927592 0.913 rs7106339 chr11:68240241 C/T cg20283391 chr11:68216788 NA -0.51 -7.49 -0.38 5.8e-13 Total body bone mineral density; LIHC cis rs2439831 0.867 rs2927072 chr15:43922398 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.98 0.35 1.56e-11 Lung cancer in ever smokers; LIHC cis rs1005277 0.579 rs2472174 chr10:38375382 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs11677370 0.561 rs11687254 chr2:3830906 C/T cg17052675 chr2:3827356 NA -0.59 -7.64 -0.38 2.14e-13 Type 2 diabetes; LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg13395646 chr4:1353034 KIAA1530 -0.48 -7.6 -0.38 2.85e-13 Obesity-related traits; LIHC cis rs72843506 1.000 rs72843506 chr17:19946287 T/A cg12065943 chr17:19881925 AKAP10 -0.33 -6.1 -0.31 2.91e-9 Schizophrenia; LIHC cis rs4908768 0.539 rs7547411 chr1:8638145 A/G cg20416874 chr1:8611966 RERE -0.62 -12.2 -0.55 1.11e-28 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs61990749 0.571 rs11628049 chr14:78308451 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.48 -7.43 -0.37 8.82e-13 Fibroblast growth factor basic levels; LIHC cis rs939574 1.000 rs45488900 chr2:220116509 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.0 10.47 0.49 1.95e-22 Platelet distribution width; LIHC cis rs1355223 0.902 rs34610590 chr11:34725440 T/C cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.43 -0.33 4.36e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg18306943 chr3:40428807 ENTPD3 0.34 5.84 0.3 1.23e-8 Renal cell carcinoma; LIHC cis rs12497850 0.931 rs9876848 chr3:48844059 G/A cg06212747 chr3:49208901 KLHDC8B 0.55 7.02 0.35 1.21e-11 Parkinson's disease; LIHC cis rs9649465 0.967 rs598115 chr7:123402603 C/G cg03229431 chr7:123269106 ASB15 0.39 8.27 0.41 3.06e-15 Migraine; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg14709524 chr16:89940631 TCF25 0.59 7.57 0.38 3.43e-13 Skin colour saturation; LIHC cis rs9368481 0.700 rs6911401 chr6:26913214 C/G cg18867708 chr6:26865862 GUSBL1 0.54 8.16 0.4 6.42e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs921968 0.612 rs573555 chr2:219348888 A/C cg02985541 chr2:219472218 PLCD4 0.46 8.73 0.43 1.18e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg06238570 chr21:40685208 BRWD1 0.6 7.1 0.36 7.19e-12 Cognitive function; LIHC cis rs4474465 0.703 rs10899547 chr11:78254720 C/T cg27205649 chr11:78285834 NARS2 0.4 6.25 0.32 1.22e-9 Alzheimer's disease (survival time); LIHC cis rs61990749 0.597 rs11623088 chr14:78137735 G/A cg21497246 chr14:78225524 SNW1;C14orf178 0.49 7.48 0.37 6.46e-13 Fibroblast growth factor basic levels; LIHC cis rs9916302 0.808 rs12947281 chr17:37652210 G/T cg00129232 chr17:37814104 STARD3 -0.41 -6.61 -0.34 1.45e-10 Glomerular filtration rate (creatinine); LIHC cis rs6089829 0.962 rs6011544 chr20:61658782 T/C cg08564027 chr20:61660810 NA 0.4 7.71 0.38 1.42e-13 Prostate cancer (SNP x SNP interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11708118 chr12:6862968 MLF2 -0.46 -6.08 -0.31 3.18e-9 Pancreatic cancer; LIHC cis rs1577917 0.771 rs4383777 chr6:86435960 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 10.17 0.48 2.17e-21 Response to antipsychotic treatment; LIHC cis rs2153535 0.601 rs9505472 chr6:8538765 T/C cg07606381 chr6:8435919 SLC35B3 0.78 11.28 0.52 2.74e-25 Motion sickness; LIHC cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg20887711 chr4:1340912 KIAA1530 0.79 12.52 0.56 7.17e-30 Longevity; LIHC cis rs8084351 0.524 rs1811358 chr18:50768168 G/A cg24270629 chr18:50823537 DCC -0.46 -6.83 -0.35 3.95e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2297440 0.530 rs34533955 chr20:62233020 A/C cg16989086 chr20:62203971 PRIC285 0.57 8.23 0.41 3.97e-15 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC cis rs847649 0.842 rs4729873 chr7:102731781 G/A cg18108683 chr7:102477205 FBXL13 0.46 6.9 0.35 2.54e-11 Morning vs. evening chronotype; LIHC cis rs6815814 0.950 rs5743566 chr4:38805942 G/C cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC trans rs10411161 0.702 rs8100716 chr19:52384061 T/C cg22319618 chr22:45562946 NUP50 -0.6 -8.19 -0.4 5.12e-15 Breast cancer; LIHC cis rs1728785 1.000 rs1170436 chr16:68607486 T/A cg02972257 chr16:68554789 NA -0.52 -5.83 -0.3 1.32e-8 Ulcerative colitis; LIHC cis rs2836974 0.666 rs4818015 chr21:40675493 A/C cg11890956 chr21:40555474 PSMG1 0.5 7.78 0.39 8.6e-14 Cognitive function; LIHC cis rs8141529 0.748 rs132528 chr22:29295898 C/T cg02153584 chr22:29168773 CCDC117 -0.52 -8.09 -0.4 1.08e-14 Lymphocyte counts; LIHC cis rs4755351 0.504 rs7945332 chr11:33188153 A/C cg05567920 chr11:33183001 CSTF3 0.43 6.35 0.32 6.88e-10 Lung cancer in ever smokers; LIHC cis rs1707322 1.000 rs11211228 chr1:46399840 G/A cg03146154 chr1:46216737 IPP 0.48 7.74 0.39 1.13e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2832191 0.765 rs2832162 chr21:30461808 G/A cg24692254 chr21:30365293 RNF160 0.65 11.73 0.54 6.4e-27 Dental caries; LIHC cis rs11628318 0.614 rs11847932 chr14:103185435 T/G cg23461800 chr14:103021989 NA 0.45 6.12 0.31 2.6e-9 Platelet count; LIHC cis rs909341 0.763 rs1291209 chr20:62330439 T/C cg03999872 chr20:62272968 STMN3 -0.46 -6.76 -0.34 6.08e-11 Atopic dermatitis; LIHC cis rs1707322 0.717 rs1547925 chr1:46085356 C/T cg06784218 chr1:46089804 CCDC17 -0.42 -7.73 -0.39 1.18e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7534824 0.543 rs60978318 chr1:101400413 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.64 7.44 0.37 8.13e-13 Refractive astigmatism; LIHC cis rs796364 1.000 rs1658807 chr2:200767512 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.71 8.3 0.41 2.39e-15 Schizophrenia; LIHC cis rs7582720 1.000 rs72934714 chr2:203711581 T/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.03 0.31 4.27e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6582630 0.555 rs11613249 chr12:38519339 T/C cg13010199 chr12:38710504 ALG10B 0.45 6.1 0.31 2.85e-9 Drug-induced liver injury (flucloxacillin); LIHC trans rs1814175 0.791 rs10839468 chr11:49986288 A/G cg03929089 chr4:120376271 NA -0.89 -18.75 -0.71 1.95e-54 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16113047 chr5:36151301 SKP2;LMBRD2 0.42 6.08 0.31 3.26e-9 Pancreatic cancer; LIHC cis rs12602486 1.000 rs76926880 chr17:42247377 C/G cg08193365 chr17:42277699 NA 1.05 7.39 0.37 1.16e-12 Glycated hemoglobin levels; LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg07157834 chr1:205819609 PM20D1 0.66 9.79 0.47 4.08e-20 Menarche (age at onset); LIHC cis rs6582630 0.502 rs8186661 chr12:38380781 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 2.97e-23 Drug-induced liver injury (flucloxacillin); LIHC trans rs2727020 0.786 rs10839263 chr11:49354462 A/G cg15704280 chr7:45808275 SEPT13 -0.74 -11.11 -0.51 1.06e-24 Coronary artery disease; LIHC cis rs56104184 0.887 rs4801778 chr19:49370609 G/T cg21252483 chr19:49399788 TULP2 -0.78 -9.73 -0.47 6.48e-20 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16157530 chr2:105654526 MRPS9 0.53 7.02 0.35 1.18e-11 Lung function (FEV1/FVC); LIHC cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg18357526 chr6:26021779 HIST1H4A 0.83 11.33 0.52 1.79e-25 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs11659028 chr17:41195025 T/A cg25072359 chr17:41440525 NA 0.38 5.98 0.31 5.67e-9 Menopause (age at onset); LIHC trans rs916888 0.779 rs430685 chr17:44859148 T/C cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7829975 0.564 rs2921057 chr8:8318667 C/T cg06636001 chr8:8085503 FLJ10661 0.73 11.3 0.52 2.26e-25 Mood instability; LIHC cis rs7309 0.935 rs6432674 chr2:162025322 G/T cg21518248 chr2:162101506 NA 0.46 7.09 0.36 7.93e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs1577917 0.739 rs9344532 chr6:86234070 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 11.78 0.54 3.95e-27 Response to antipsychotic treatment; LIHC cis rs10883723 0.810 rs2296588 chr10:104248087 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.08 0.58 5.66e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs611744 0.967 rs653633 chr8:109196151 T/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs1814175 0.817 rs3974439 chr11:50022607 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC cis rs4845459 0.967 rs6693105 chr1:152590663 C/T cg20634798 chr1:152595351 LCE3A 0.29 5.74 0.3 2.09e-8 Psoriasis; LIHC cis rs7258465 1.000 rs8106096 chr19:18536416 C/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.16 -0.36 4.96e-12 Breast cancer; LIHC cis rs2153535 0.601 rs1737581 chr6:8539138 A/G cg23788917 chr6:8435910 SLC35B3 0.62 8.66 0.42 1.89e-16 Motion sickness; LIHC cis rs10174077 0.874 rs4664490 chr2:152471923 C/G cg06191203 chr2:152266755 RIF1 0.38 6.58 0.34 1.78e-10 Squamous cell lung carcinoma; LIHC cis rs1552244 0.572 rs66514627 chr3:10166632 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs1801251 1.000 rs2592102 chr2:233726772 G/T cg25237894 chr2:233734115 C2orf82 -0.58 -11.33 -0.52 1.73e-25 Coronary artery disease; LIHC cis rs17756712 0.615 rs3823127 chr6:593841 T/C cg14374089 chr6:596013 EXOC2 -0.5 -6.53 -0.33 2.43e-10 Vertical cup-disc ratio; LIHC cis rs11792861 0.926 rs118011482 chr9:111770626 G/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.76 -0.34 5.92e-11 Menarche (age at onset); LIHC cis rs7312774 0.881 rs60941459 chr12:107318583 T/C cg16260113 chr12:107380972 MTERFD3 0.8 10.36 0.49 4.84e-22 Severe influenza A (H1N1) infection; LIHC trans rs9929218 0.953 rs12920562 chr16:68737512 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.17 -0.44 4.46e-18 Colorectal cancer; LIHC cis rs6504950 0.745 rs12603899 chr17:53010098 T/C cg10237252 chr17:52977213 TOM1L1 -0.34 -5.99 -0.31 5.22e-9 Breast cancer; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg05185784 chr16:90016020 DEF8 -0.45 -5.84 -0.3 1.21e-8 Skin colour saturation; LIHC cis rs6840360 0.615 rs113052419 chr4:152473008 T/C cg22705602 chr4:152727874 NA -0.33 -6.53 -0.33 2.43e-10 Intelligence (multi-trait analysis); LIHC cis rs7940866 0.803 rs1865296 chr11:130882944 C/T cg12179176 chr11:130786555 SNX19 -0.55 -8.12 -0.4 8.75e-15 Schizophrenia; LIHC trans rs11098499 0.863 rs3736115 chr4:120488703 A/G cg25214090 chr10:38739885 LOC399744 -0.51 -7.97 -0.4 2.44e-14 Corneal astigmatism; LIHC cis rs1728785 0.901 rs11865339 chr16:68565296 C/T cg02972257 chr16:68554789 NA -0.53 -6.19 -0.32 1.73e-9 Ulcerative colitis; LIHC cis rs7267979 0.966 rs2261790 chr20:25262789 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs911119 1.000 rs911119 chr20:23612737 C/T cg16589663 chr20:23618590 CST3 -0.75 -7.96 -0.4 2.6e-14 Chronic kidney disease; LIHC cis rs6570726 0.935 rs425717 chr6:145838620 A/T cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs35892873 0.703 rs7615776 chr3:126060617 G/A cg15490784 chr3:126061950 KLF15 0.46 6.82 0.35 4.05e-11 Male-pattern baldness; LIHC cis rs644799 0.965 rs549695 chr11:95617788 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.0 0.65 2.08e-43 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6831352 0.918 rs4699714 chr4:100060538 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs13108904 0.518 rs4974602 chr4:1342391 C/T cg00684032 chr4:1343700 KIAA1530 0.58 8.47 0.42 7.25e-16 Obesity-related traits; LIHC cis rs7116495 0.881 rs673478 chr11:71799104 G/A cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs2439831 0.702 rs3784275 chr15:44091386 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.57 6.25 0.32 1.21e-9 Lung cancer in ever smokers; LIHC cis rs1348850 0.560 rs13019660 chr2:178498214 C/T cg27490568 chr2:178487706 NA 0.67 8.76 0.43 9.27e-17 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs75920871 0.528 rs4388921 chr11:116976778 T/C cg01368799 chr11:117014884 PAFAH1B2 -0.45 -5.9 -0.3 8.85e-9 Subjective well-being; LIHC cis rs7223966 1.000 rs11542436 chr17:61778689 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.54 6.27 0.32 1.1e-9 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg26705765 chr19:10252866 DNMT1 0.51 6.51 0.33 2.73e-10 Hip circumference; LIHC cis rs11098499 0.909 rs73842633 chr4:120375464 G/A cg09307838 chr4:120376055 NA 0.76 11.7 0.53 8.12e-27 Corneal astigmatism; LIHC cis rs4819052 0.851 rs9974628 chr21:46672647 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.78 0.39 8.95e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg21644426 chr2:191273491 MFSD6 0.55 7.71 0.38 1.43e-13 Pulse pressure; LIHC cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg26874164 chr19:58962979 ZNF324B 0.6 9.04 0.44 1.16e-17 Uric acid clearance; LIHC cis rs425277 0.606 rs262669 chr1:2082489 A/G cg24578937 chr1:2090814 PRKCZ -0.31 -5.74 -0.3 2.08e-8 Height; LIHC cis rs9660992 0.547 rs12143121 chr1:205199142 A/G cg21545522 chr1:205238299 TMCC2 0.37 6.99 0.35 1.47e-11 Mean corpuscular volume;Mean platelet volume; LIHC cis rs67981189 0.593 rs12896829 chr14:71463676 G/C cg15816911 chr14:71606274 NA 0.41 6.59 0.34 1.65e-10 Schizophrenia; LIHC trans rs2579103 0.767 rs1371085 chr12:90665505 T/G cg00091569 chr3:40428383 ENTPD3 0.37 6.05 0.31 3.8e-9 Body mass index; LIHC cis rs853679 0.517 rs35193936 chr6:28076270 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs78456975 1.000 rs10177095 chr2:1570976 C/A cg01028140 chr2:1542097 TPO -0.48 -5.89 -0.3 9.04e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs12478296 1.000 rs60533128 chr2:243028088 A/G cg06360820 chr2:242988706 NA -0.95 -12.18 -0.55 1.38e-28 Obesity-related traits; LIHC cis rs10744422 0.858 rs4759389 chr12:123308615 A/G cg25930673 chr12:123319894 HIP1R -0.85 -10.96 -0.51 3.66e-24 Schizophrenia; LIHC trans rs28735056 0.609 rs4799099 chr18:77639585 A/G cg05926928 chr17:57297772 GDPD1 0.5 7.3 0.37 2e-12 Schizophrenia; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC cis rs763121 0.925 rs9835 chr22:39130971 A/G cg06022373 chr22:39101656 GTPBP1 0.63 11.97 0.54 8.3e-28 Menopause (age at onset); LIHC cis rs4665809 1.000 rs4665304 chr2:26313406 C/T cg27170947 chr2:26402098 FAM59B -0.61 -7.71 -0.38 1.39e-13 Gut microbiome composition (summer); LIHC cis rs4689592 0.554 rs3951346 chr4:7073321 C/T cg06697600 chr4:7070879 GRPEL1 -0.66 -10.7 -0.5 3.13e-23 Monocyte percentage of white cells; LIHC cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg00149659 chr3:10157352 C3orf10 0.75 7.65 0.38 2.1e-13 Alzheimer's disease; LIHC cis rs751728 1.000 rs3793079 chr6:33767788 T/A cg25922239 chr6:33757077 LEMD2 0.44 7.57 0.38 3.41e-13 Crohn's disease; LIHC cis rs2012796 0.743 rs12435764 chr14:81836866 A/C cg23690444 chr14:81902736 NA -0.44 -6.38 -0.33 5.66e-10 Night sleep phenotypes; LIHC cis rs17106184 0.786 rs72900944 chr1:51126914 C/T cg07174182 chr1:51127561 FAF1 -0.76 -8.12 -0.4 8.47e-15 Type 2 diabetes; LIHC cis rs4148883 0.504 rs2000864 chr4:100123776 A/C cg12011299 chr4:100065546 ADH4 0.32 6.61 0.34 1.46e-10 Alcohol dependence; LIHC cis rs16958440 1.000 rs11082563 chr18:44659001 T/C cg17192377 chr18:44677553 HDHD2 0.58 6.48 0.33 3.25e-10 Sitting height ratio; LIHC cis rs9425766 0.546 rs6691001 chr1:173819076 T/G cg06124660 chr1:173389066 NA -0.34 -6.61 -0.34 1.44e-10 Life satisfaction; LIHC cis rs6840360 0.967 rs6535815 chr4:152609700 A/C cg22705602 chr4:152727874 NA -0.31 -6.62 -0.34 1.39e-10 Intelligence (multi-trait analysis); LIHC cis rs2070488 1.000 rs34258593 chr3:38464565 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.74 0.65 2.24e-42 Electrocardiographic conduction measures; LIHC cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg03264133 chr6:25882463 NA -0.6 -8.4 -0.41 1.21e-15 Blood metabolite levels; LIHC cis rs57502260 0.651 rs3781586 chr11:68199393 C/A cg16797656 chr11:68205561 LRP5 0.65 8.81 0.43 6.49e-17 Total body bone mineral density (age 45-60); LIHC cis rs853679 0.517 rs9393888 chr6:28059217 G/C cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs6500602 0.826 rs9925719 chr16:4461861 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.09 0.31 3.06e-9 Schizophrenia; LIHC cis rs4746818 0.892 rs2394505 chr10:70871598 A/G cg11621586 chr10:70884670 VPS26A -0.71 -10.89 -0.51 6.63e-24 Left atrial antero-posterior diameter; LIHC cis rs7845219 0.544 rs4735332 chr8:95923660 C/T cg13393036 chr8:95962371 TP53INP1 -0.32 -6.31 -0.32 8.74e-10 Type 2 diabetes; LIHC cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg27286337 chr10:134555280 INPP5A -0.91 -12.63 -0.56 2.86e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9783347 0.925 rs3825025 chr11:18343822 C/G cg15585147 chr11:18324498 HPS5 0.43 6.65 0.34 1.18e-10 Pancreatic cancer; LIHC cis rs35306767 0.903 rs12240651 chr10:943656 A/G cg26597838 chr10:835615 NA 1.18 13.84 0.6 6.79e-35 Eosinophil percentage of granulocytes; LIHC cis rs12586317 0.547 rs76770287 chr14:35487210 C/A cg05294307 chr14:35346193 BAZ1A -0.49 -7.42 -0.37 9.63e-13 Psoriasis; LIHC cis rs10789491 1.000 rs10789491 chr1:47179310 A/G cg15501359 chr1:47185051 KIAA0494 0.78 11.05 0.51 1.79e-24 Response to hepatitis C treatment; LIHC trans rs12555078 1.000 rs62542261 chr9:76085629 G/A cg06169179 chr9:2717946 KCNV2 0.8 6.33 0.32 7.87e-10 Obesity-related traits; LIHC cis rs769267 0.899 rs3934667 chr19:19431423 T/G cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.39 -0.33 5.54e-10 Tonsillectomy; LIHC cis rs2050392 0.799 rs303429 chr10:30708441 C/T cg25182066 chr10:30743637 MAP3K8 -0.47 -7.66 -0.38 1.89e-13 Inflammatory bowel disease; LIHC cis rs7927771 0.864 rs2868459 chr11:47454972 C/G cg20135002 chr11:47629003 NA -0.57 -9.61 -0.46 1.58e-19 Subjective well-being; LIHC cis rs595982 0.501 rs112370206 chr19:49396623 C/T cg21252483 chr19:49399788 TULP2 -0.6 -9.41 -0.45 7.76e-19 Red cell distribution width; LIHC cis rs12458462 0.892 rs12456692 chr18:77482189 C/T cg11879182 chr18:77439856 CTDP1 0.82 13.76 0.6 1.37e-34 Monocyte count; LIHC cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg11764359 chr7:65958608 NA 0.57 6.03 0.31 4.16e-9 Diabetic kidney disease; LIHC cis rs765787 0.530 rs1648287 chr15:45516956 T/C cg25801113 chr15:45476975 SHF 0.4 6.82 0.35 4.22e-11 Uric acid levels; LIHC cis rs7098414 0.511 rs4934126 chr10:82151598 A/G cg00277334 chr10:82204260 NA -0.61 -10.14 -0.48 2.58e-21 Post bronchodilator FEV1; LIHC cis rs1816752 0.870 rs9318529 chr13:24998328 A/G cg22771759 chr13:24902376 NA 0.32 6.49 0.33 3.03e-10 Obesity-related traits; LIHC cis rs950776 0.507 rs12912673 chr15:78810216 T/C cg22563815 chr15:78856949 CHRNA5 0.35 6.26 0.32 1.13e-9 Sudden cardiac arrest; LIHC cis rs769267 0.929 rs34538000 chr19:19481379 G/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.53 -8.13 -0.4 8.08e-15 Tonsillectomy; LIHC cis rs7619427 1.000 rs7643455 chr3:44073001 T/C cg24966902 chr3:44043705 NA 0.52 7.4 0.37 1.06e-12 Schizophrenia; LIHC cis rs12915845 0.584 rs17196732 chr15:89069299 A/C cg05013243 chr15:89149849 MIR1179 0.39 7.11 0.36 6.62e-12 Menarche (age at onset); LIHC cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg24549020 chr5:56110836 MAP3K1 0.52 6.69 0.34 8.87e-11 Initial pursuit acceleration; LIHC cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg13047869 chr3:10149882 C3orf24 0.53 6.83 0.35 3.97e-11 Alzheimer's disease; LIHC cis rs7542091 0.704 rs4133950 chr1:210044393 C/G cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs11792861 0.926 rs1051474 chr9:111881856 T/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.83 -0.35 3.9e-11 Menarche (age at onset); LIHC cis rs1403694 0.695 rs1851664 chr3:186436503 T/A cg12454167 chr3:186435060 KNG1 0.37 8.65 0.42 1.99e-16 Blood protein levels; LIHC cis rs1552244 0.882 rs55840655 chr3:10042690 C/T cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs1046896 0.562 rs9912684 chr17:80873067 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.4 6.0 0.31 4.94e-9 Glycated hemoglobin levels; LIHC cis rs2625529 0.824 rs12592364 chr15:72284647 C/A cg16672083 chr15:72433130 SENP8 -0.3 -5.78 -0.3 1.73e-8 Red blood cell count; LIHC cis rs2153535 0.580 rs7761937 chr6:8459434 A/T cg21535247 chr6:8435926 SLC35B3 0.68 8.88 0.43 3.74e-17 Motion sickness; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg11494091 chr17:61959527 GH2 0.44 8.25 0.41 3.48e-15 Prudent dietary pattern; LIHC cis rs3820068 0.581 rs72645888 chr1:15929922 C/A cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03353000 chr22:41252913 ST13;XPNPEP3 -0.51 -7.0 -0.35 1.39e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs17270561 1.000 rs79867288 chr6:25828416 A/G cg17691542 chr6:26056736 HIST1H1C 0.71 7.98 0.4 2.23e-14 Iron status biomarkers; LIHC cis rs4629710 0.592 rs11758994 chr6:131582022 A/C cg12606694 chr6:131520996 AKAP7 0.61 7.11 0.36 6.95e-12 Multiple myeloma (IgH translocation); LIHC cis rs11971779 0.555 rs4728466 chr7:139096365 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs523522 0.962 rs4767912 chr12:120981202 A/G cg12219531 chr12:120966889 COQ5 0.67 13.33 0.58 6.32e-33 High light scatter reticulocyte count; LIHC cis rs8062405 0.964 rs9972768 chr16:28861734 A/C cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg05590025 chr7:65112418 INTS4L2 -0.63 -7.05 -0.36 9.75e-12 Diabetic kidney disease; LIHC cis rs3020736 0.500 rs2413672 chr22:42513261 C/T cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.2 -0.32 1.67e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg21724239 chr8:58056113 NA 0.64 7.89 0.39 4.03e-14 Developmental language disorder (linguistic errors); LIHC cis rs9660992 0.710 rs1668872 chr1:205236069 G/A cg21545522 chr1:205238299 TMCC2 0.43 8.13 0.4 8.01e-15 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2645694 0.626 rs2703118 chr4:77823672 A/G cg03477792 chr4:77819574 ANKRD56 0.58 8.44 0.42 8.97e-16 Emphysema distribution in smoking; LIHC cis rs62380364 0.542 rs2247885 chr5:88047999 T/C cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis); LIHC trans rs2243480 1.000 rs313798 chr7:65493031 A/G cg10756647 chr7:56101905 PSPH 1.08 13.33 0.58 5.93e-33 Diabetic kidney disease; LIHC cis rs769267 1.000 rs7247309 chr19:19439631 A/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.62 -10.11 -0.48 3.31e-21 Tonsillectomy; LIHC trans rs116095464 0.614 rs56299325 chr5:220594 C/T cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs858239 0.600 rs7341483 chr7:23127657 G/T cg23682824 chr7:23144976 KLHL7 -0.43 -6.55 -0.33 2.08e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs17685 0.753 rs10245584 chr7:75745866 C/T cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1577917 0.958 rs12197463 chr6:86445242 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 4.83e-15 Response to antipsychotic treatment; LIHC cis rs7772486 0.875 rs11155452 chr6:146424631 C/T cg05347473 chr6:146136440 FBXO30 0.38 5.99 0.31 5.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2637030 0.542 rs429384 chr5:52908205 A/G cg06476337 chr5:52856530 NDUFS4 0.43 6.81 0.35 4.3e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs3008870 1.000 rs2755246 chr1:67488984 A/G cg02640540 chr1:67518911 SLC35D1 0.46 6.32 0.32 8.37e-10 Lymphocyte percentage of white cells; LIHC cis rs4906332 0.966 rs12588705 chr14:103865477 T/A cg19000871 chr14:103996768 TRMT61A -0.45 -7.56 -0.38 3.63e-13 Coronary artery disease; LIHC cis rs2839186 0.587 rs35679325 chr21:47640980 A/G cg12379764 chr21:47803548 PCNT 0.55 8.01 0.4 1.78e-14 Testicular germ cell tumor; LIHC trans rs2727020 0.731 rs10450572 chr11:49281073 T/C cg15704280 chr7:45808275 SEPT13 0.9 16.55 0.67 1.33e-45 Coronary artery disease; LIHC cis rs1003719 0.788 rs1543749 chr21:38446621 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg06697600 chr4:7070879 GRPEL1 -0.66 -10.45 -0.49 2.36e-22 Monocyte percentage of white cells; LIHC cis rs1163251 0.837 rs658442 chr1:120244858 T/G cg19096424 chr1:120255104 PHGDH 0.63 8.1 0.4 9.82e-15 Blood metabolite levels; LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs2576037 0.526 rs7234570 chr18:44459656 A/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.99e-10 Personality dimensions; LIHC cis rs6748734 0.857 rs10933638 chr2:241794655 G/A cg04034577 chr2:241836375 C2orf54 -0.45 -10.22 -0.48 1.41e-21 Urinary metabolites; LIHC cis rs7572733 0.534 rs700692 chr2:198728500 T/C cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs2084898 0.550 rs470411 chr11:120012390 G/C cg16005559 chr11:120040616 NA -0.45 -6.9 -0.35 2.56e-11 Stroke (pediatric); LIHC cis rs250677 0.687 rs384979 chr5:148459267 C/T cg18129178 chr5:148520854 ABLIM3 0.47 7.32 0.37 1.79e-12 Breast cancer; LIHC cis rs9612 1.000 rs2074634 chr19:44238347 C/T cg08581076 chr19:44259116 C19orf61 -0.54 -6.39 -0.33 5.39e-10 Exhaled nitric oxide output; LIHC cis rs9303401 1.000 rs6503882 chr17:56915761 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 7.04 0.36 1.03e-11 Cognitive test performance; LIHC trans rs1728785 0.688 rs7203363 chr16:68587692 T/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.36 0.33 6.63e-10 Ulcerative colitis; LIHC cis rs9811920 0.609 rs793463 chr3:99620252 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.49 -6.82 -0.35 4.07e-11 Axial length; LIHC cis rs12220238 0.554 rs11001029 chr10:76154777 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.76 0.3 1.85e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs12497850 0.931 rs4974080 chr3:49030828 A/C cg07636037 chr3:49044803 WDR6 0.93 15.62 0.65 6.82e-42 Parkinson's disease; LIHC cis rs9322817 0.691 rs2499652 chr6:105269959 G/A cg02098413 chr6:105308735 HACE1 0.42 7.82 0.39 6.45e-14 Thyroid stimulating hormone; LIHC cis rs4665809 1.000 rs11678157 chr2:26321526 T/C cg04944784 chr2:26401820 FAM59B -0.64 -8.22 -0.41 4.31e-15 Gut microbiome composition (summer); LIHC cis rs9814567 1.000 rs13087875 chr3:134261123 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9625935 0.518 rs9625870 chr22:30261219 C/T cg01021169 chr22:30184971 ASCC2 -0.37 -6.37 -0.33 6.1e-10 Tonsillectomy; LIHC cis rs11098499 0.863 rs12508173 chr4:120318526 T/C cg09307838 chr4:120376055 NA 0.76 11.65 0.53 1.25e-26 Corneal astigmatism; LIHC cis rs7945705 0.935 rs2568061 chr11:8886260 A/G cg12365402 chr11:9010492 NRIP3 -0.25 -6.3 -0.32 9.39e-10 Hemoglobin concentration; LIHC cis rs7729447 0.813 rs4867121 chr5:32692548 T/C cg16267343 chr5:32710456 NPR3 0.47 5.76 0.3 1.88e-8 Blood pressure; LIHC cis rs9325144 0.600 rs61931871 chr12:38829889 G/A cg26384229 chr12:38710491 ALG10B -0.57 -7.66 -0.38 1.99e-13 Morning vs. evening chronotype; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12976413 chr7:75544151 POR 0.42 6.07 0.31 3.42e-9 Lung function (FEV1/FVC); LIHC cis rs1371867 0.846 rs2439460 chr8:101312665 C/T cg06002616 chr8:101225028 SPAG1 -0.34 -5.81 -0.3 1.43e-8 Atrioventricular conduction; LIHC cis rs11585357 0.842 rs72633804 chr1:17617024 T/C cg08277548 chr1:17600880 PADI3 -0.64 -6.77 -0.34 5.59e-11 Hair shape; LIHC cis rs7312933 0.703 rs1059360 chr12:42554505 A/G cg17420585 chr12:42539391 GXYLT1 -0.38 -5.98 -0.31 5.55e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs34779708 0.966 rs17591857 chr10:35499043 A/G cg03585969 chr10:35415529 CREM -0.85 -12.66 -0.56 2.15e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs67460515 0.500 rs9860537 chr3:160660500 G/T cg03342759 chr3:160939853 NMD3 0.49 6.91 0.35 2.45e-11 Parkinson's disease; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.06 0.55 3.69e-28 Prudent dietary pattern; LIHC cis rs6088580 0.634 rs6058070 chr20:33103521 G/C cg08999081 chr20:33150536 PIGU 0.68 13.52 0.59 1.12e-33 Glomerular filtration rate (creatinine); LIHC cis rs847649 0.842 rs4729860 chr7:102625567 C/T cg18108683 chr7:102477205 FBXL13 0.47 7.06 0.36 9.27e-12 Morning vs. evening chronotype; LIHC cis rs2404602 0.692 rs35498563 chr15:76958868 C/T cg23625390 chr15:77176239 SCAPER 0.36 5.94 0.31 7.03e-9 Blood metabolite levels; LIHC cis rs1790761 0.667 rs598811 chr11:67311676 C/T cg01069141 chr11:67398826 TBX10;NUDT8 0.36 6.45 0.33 3.92e-10 Mean corpuscular volume; LIHC cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.44 -0.45 6.13e-19 Bipolar disorder and schizophrenia; LIHC cis rs7223966 1.000 rs7223412 chr17:61808172 T/C cg05941027 chr17:61774174 LIMD2 0.36 7.54 0.38 4.22e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs13108904 0.901 rs7695691 chr4:1304632 A/G cg19318889 chr4:1322082 MAEA 0.53 8.83 0.43 5.55e-17 Obesity-related traits; LIHC cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs3540 0.553 rs8042861 chr15:90977333 G/T cg22089800 chr15:90895588 ZNF774 0.62 8.48 0.42 6.79e-16 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg13047869 chr3:10149882 C3orf24 0.52 6.63 0.34 1.33e-10 Alzheimer's disease; LIHC cis rs67311347 0.955 rs6599100 chr3:40447362 C/T cg13409248 chr3:40428643 ENTPD3 0.41 6.77 0.34 5.6e-11 Renal cell carcinoma; LIHC cis rs11583043 1.000 rs7521424 chr1:101475901 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 8.64 0.42 2.21e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs896854 0.812 rs2340586 chr8:95969261 G/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.94 -0.39 2.89e-14 Type 2 diabetes; LIHC cis rs4975616 0.869 rs31484 chr5:1337906 A/T cg07493874 chr5:1342172 CLPTM1L -0.71 -11.24 -0.52 3.83e-25 Lung cancer; LIHC cis rs6690583 0.623 rs12030730 chr1:85454109 C/G cg22153463 chr1:85462885 MCOLN2 0.5 6.03 0.31 4.19e-9 Serum sulfate level; LIHC cis rs2153535 0.580 rs7763190 chr6:8484197 G/A cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs7937682 0.632 rs7128862 chr11:111755435 C/T cg09085632 chr11:111637200 PPP2R1B 0.93 13.38 0.59 3.93e-33 Primary sclerosing cholangitis; LIHC trans rs2727020 0.514 rs4980444 chr11:49550764 T/A cg18944383 chr4:111397179 ENPEP 0.25 6.16 0.32 1.99e-9 Coronary artery disease; LIHC cis rs2737618 0.722 rs2821333 chr1:200093253 A/C cg21825944 chr1:200113062 NR5A2 -0.41 -6.63 -0.34 1.32e-10 Uric acid levels; LIHC cis rs10864907 0.614 rs10199311 chr2:113697961 C/T cg12858261 chr2:113808755 IL1F8 0.34 6.03 0.31 4.21e-9 Pulmonary function; LIHC cis rs3762637 0.823 rs9849013 chr3:122250605 A/G cg24169773 chr3:122142474 KPNA1 -0.46 -9.0 -0.44 1.54e-17 LDL cholesterol levels; LIHC trans rs60843830 1.000 rs3791224 chr2:221981 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.6 8.5 0.42 6.13e-16 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs4820539 0.611 rs28451783 chr22:23488569 G/T cg21100191 chr22:23484243 RTDR1 0.79 8.91 0.43 3.09e-17 Bone mineral density; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg07755735 chr2:20870362 GDF7 0.41 9.28 0.45 2.01e-18 Abdominal aortic aneurysm; LIHC cis rs17685 0.725 rs7807647 chr7:75628669 G/A cg01364799 chr7:75623366 TMEM120A 0.54 8.41 0.41 1.16e-15 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs801193 0.967 rs1110414 chr7:66205582 A/G cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.89e-11 Aortic root size; LIHC cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg20607798 chr8:58055168 NA 0.73 8.56 0.42 3.79e-16 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg00149659 chr3:10157352 C3orf10 0.95 8.46 0.42 8.08e-16 Alzheimer's disease; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg07677032 chr17:61819896 STRADA 0.43 6.4 0.33 5.04e-10 Prudent dietary pattern; LIHC cis rs72781680 0.898 rs72780188 chr2:24006065 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs2404602 0.716 rs12438077 chr15:76863601 T/C cg03037974 chr15:76606532 NA 0.74 14.47 0.62 2.32e-37 Blood metabolite levels; LIHC cis rs4820294 0.770 rs7285699 chr22:38066556 A/C cg00142150 chr22:38071001 LGALS1 0.44 7.43 0.37 8.99e-13 Fat distribution (HIV); LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.78 0.62 1.38e-38 Prudent dietary pattern; LIHC cis rs7607369 0.566 rs55658481 chr2:219284215 G/A cg02176678 chr2:219576539 TTLL4 -0.5 -6.86 -0.35 3.33e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs3824867 0.920 rs7105122 chr11:47449544 A/G cg20307385 chr11:47447363 PSMC3 0.58 7.87 0.39 4.71e-14 Mean corpuscular hemoglobin; LIHC cis rs17152411 0.895 rs3940439 chr10:126584531 C/G cg07906193 chr10:126599966 NA 0.43 6.94 0.35 1.93e-11 Height; LIHC cis rs11785693 0.862 rs11778306 chr8:4988269 A/C cg26367366 chr8:4980734 NA 0.63 6.76 0.34 5.97e-11 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs11792861 0.926 rs11787878 chr9:111866749 C/T cg05043794 chr9:111880884 C9orf5 -0.31 -7.23 -0.36 3.24e-12 Menarche (age at onset); LIHC cis rs4319547 0.656 rs3817011 chr12:122819566 C/T cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.59 -0.38 3.15e-13 Body mass index; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg05134769 chr7:2239818 MAD1L1 0.5 6.07 0.31 3.43e-9 Lung function (FEV1); LIHC cis rs7937890 0.904 rs7484197 chr11:14283654 C/T cg02886208 chr11:14281011 SPON1 -0.62 -9.18 -0.44 4.24e-18 Mitochondrial DNA levels; LIHC cis rs7474896 0.559 rs10740949 chr10:37978435 A/G cg25427524 chr10:38739819 LOC399744 -0.49 -7.22 -0.36 3.35e-12 Obesity (extreme); LIHC cis rs4925386 1.000 rs6089351 chr20:60916153 G/A cg06026331 chr20:60912101 LAMA5 -0.51 -8.54 -0.42 4.58e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs9902453 0.904 rs6505148 chr17:28289818 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.71 0.6 2.2e-34 Coffee consumption (cups per day); LIHC cis rs6426558 0.524 rs2813948 chr1:227459621 A/T cg10327440 chr1:227177885 CDC42BPA 0.41 6.32 0.32 7.98e-10 Neutrophil percentage of white cells; LIHC cis rs9443189 0.737 rs2842553 chr6:76456632 A/T cg01950844 chr6:76311363 SENP6 -0.52 -6.64 -0.34 1.2e-10 Prostate cancer; LIHC cis rs8192917 0.887 rs2236337 chr14:25100247 T/C cg03875678 chr14:25103546 GZMB 0.4 7.38 0.37 1.21e-12 Vitiligo; LIHC cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg24531977 chr5:56204891 C5orf35 -0.59 -8.42 -0.41 1.08e-15 Initial pursuit acceleration; LIHC cis rs11760633 0.672 rs12669620 chr7:1826878 G/C cg23422044 chr7:1970798 MAD1L1 -0.37 -5.73 -0.3 2.26e-8 Coronary artery disease; LIHC trans rs1814175 0.645 rs7952104 chr11:49964180 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs11577318 0.528 rs11247935 chr1:26698622 G/C cg18121669 chr1:26560928 CCDC21 -0.46 -6.85 -0.35 3.49e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs428668 0.681 rs428064 chr5:150696498 G/A cg11125805 chr5:150678162 SLC36A3 0.39 8.03 0.4 1.63e-14 Skin aging (microtopography measurement); LIHC cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.47 0.33 3.45e-10 Bipolar disorder; LIHC cis rs7666738 0.570 rs1869351 chr4:99077286 T/C cg05340658 chr4:99064831 C4orf37 0.65 11.67 0.53 1.07e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs732505 0.764 rs28528202 chr19:5583129 A/G cg26242866 chr19:5711310 LONP1 0.83 6.11 0.31 2.65e-9 vWF and FVIII levels; LIHC cis rs858239 0.600 rs61292332 chr7:23131862 C/T cg23682824 chr7:23144976 KLHL7 0.4 6.08 0.31 3.27e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs35110281 0.807 rs2838325 chr21:45014284 A/T cg21573476 chr21:45109991 RRP1B 0.48 9.32 0.45 1.42e-18 Mean corpuscular volume; LIHC cis rs801193 1.000 rs2707845 chr7:66198798 C/T cg14393609 chr7:65229607 NA 0.37 5.71 0.3 2.42e-8 Aortic root size; LIHC cis rs2576037 0.583 rs11659693 chr18:44458733 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.88 -0.3 9.96e-9 Personality dimensions; LIHC cis rs875971 0.928 rs2036263 chr7:65800197 C/T cg18252515 chr7:66147081 NA 0.44 6.34 0.32 7.48e-10 Aortic root size; LIHC cis rs8081395 0.627 rs12952730 chr17:57978836 G/A cg13753209 chr17:57696993 CLTC 0.49 7.82 0.39 6.61e-14 White blood cell count; LIHC cis rs3741798 1.000 rs73277486 chr12:12494761 T/C cg08615371 chr12:12503544 MANSC1 0.89 7.25 0.37 2.72e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.21e-8 Menopause (age at onset); LIHC cis rs7635838 0.718 rs2594973 chr3:11395821 C/G cg00170343 chr3:11313890 ATG7 0.55 9.14 0.44 5.87e-18 HDL cholesterol; LIHC cis rs3823572 0.564 rs2953626 chr7:133657458 A/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.71 -0.3 2.44e-8 Intelligence (multi-trait analysis); LIHC cis rs9790314 1.000 rs1382428 chr3:161032386 A/C cg03342759 chr3:160939853 NMD3 -0.7 -8.34 -0.41 1.83e-15 Morning vs. evening chronotype; LIHC cis rs7772486 0.869 rs2777473 chr6:146301494 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.65 0.46 1.17e-19 Lobe attachment (rater-scored or self-reported); LIHC trans rs7558233 0.614 rs4665214 chr2:23678795 A/G cg20638045 chr15:100107064 MEF2A 0.47 6.3 0.32 9.06e-10 Cannabis use (initiation); LIHC cis rs9902453 0.808 rs1986555 chr17:28014448 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.48 0.53 4.98e-26 Coffee consumption (cups per day); LIHC cis rs507080 0.922 rs644867 chr11:118567545 A/G cg04173919 chr11:118528438 PHLDB1 0.36 6.65 0.34 1.13e-10 Serum metabolite levels; LIHC cis rs7927592 0.956 rs7113287 chr11:68372186 A/T cg16797656 chr11:68205561 LRP5 0.52 8.27 0.41 2.91e-15 Total body bone mineral density; LIHC cis rs6748734 1.000 rs6724662 chr2:241831560 A/G cg09990169 chr2:241835740 C2orf54 -0.67 -9.61 -0.46 1.58e-19 Urinary metabolites; LIHC cis rs4407350 0.837 rs5765710 chr22:44914354 C/T cg11695653 chr22:44894386 LDOC1L 0.35 5.92 0.3 7.73e-9 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03514934 chr16:87731582 JPH3 -0.41 -6.08 -0.31 3.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs72781680 1.000 rs7581107 chr2:24173565 C/T cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs62458065 0.513 rs10245103 chr7:32534829 T/G cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -7.57 -0.38 3.48e-13 Metabolite levels (HVA/MHPG ratio); LIHC cis rs9921222 0.786 rs3848365 chr16:374617 C/T cg00101154 chr16:420108 MRPL28 -0.44 -6.02 -0.31 4.61e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg05555928 chr11:63887634 MACROD1 0.55 7.47 0.37 6.77e-13 Mean platelet volume; LIHC cis rs611744 0.967 rs681099 chr8:109218892 T/C cg18478394 chr8:109455254 TTC35 0.39 6.85 0.35 3.46e-11 Dupuytren's disease; LIHC cis rs2072499 0.778 rs2842868 chr1:156196407 A/C cg24450063 chr1:156163899 SLC25A44 0.66 7.46 0.37 7.28e-13 Testicular germ cell tumor; LIHC cis rs7917772 0.604 rs4917977 chr10:104363119 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4665809 0.549 rs3828255 chr2:26413252 G/A cg27170947 chr2:26402098 FAM59B 0.6 6.15 0.32 2.22e-9 Gut microbiome composition (summer); LIHC cis rs5769765 0.908 rs56351880 chr22:50316597 A/G cg09182678 chr22:50328711 NA -0.4 -5.92 -0.3 7.82e-9 Schizophrenia; LIHC cis rs9649465 0.967 rs6944031 chr7:123299304 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.1 -0.4 9.87e-15 Migraine; LIHC cis rs734999 0.505 rs4073286 chr1:2539901 A/C cg18854424 chr1:2615690 NA 0.33 7.4 0.37 1.04e-12 Ulcerative colitis; LIHC cis rs79976124 0.879 rs77185357 chr6:66629070 G/A cg07460842 chr6:66804631 NA 0.64 6.77 0.34 5.66e-11 Type 2 diabetes; LIHC cis rs79149102 0.579 rs73438569 chr15:75354486 T/A cg09165964 chr15:75287851 SCAMP5 -0.59 -7.73 -0.39 1.17e-13 Lung cancer; LIHC cis rs7188697 0.922 rs246258 chr16:58579274 A/G cg02549819 chr16:58548995 SETD6 0.43 6.76 0.34 5.85e-11 QT interval; LIHC cis rs11030122 0.702 rs10835402 chr11:3990914 T/C cg18678763 chr11:4115507 RRM1 -0.56 -8.28 -0.41 2.81e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs67460515 0.630 rs7638370 chr3:160921793 G/T cg17135325 chr3:160939158 NMD3 0.6 8.73 0.43 1.12e-16 Parkinson's disease; LIHC cis rs6942756 0.774 rs2566885 chr7:128917587 C/T cg02491457 chr7:128862824 NA 0.57 8.59 0.42 3.23e-16 White matter hyperintensity burden; LIHC cis rs12579753 1.000 rs7306395 chr12:82175867 A/G cg07988820 chr12:82153109 PPFIA2 -0.47 -5.89 -0.3 9.44e-9 Resting heart rate; LIHC cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg12756686 chr19:29218302 NA 0.41 7.11 0.36 6.62e-12 Methadone dose in opioid dependence; LIHC cis rs1348850 0.526 rs6723014 chr2:178410586 G/A cg27490568 chr2:178487706 NA 0.92 10.26 0.49 1.01e-21 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10540 1.000 rs61876335 chr11:488878 T/C cg03576123 chr11:487126 PTDSS2 -0.99 -7.7 -0.38 1.52e-13 Body mass index; LIHC cis rs9640161 0.830 rs36069544 chr7:150061538 G/A cg21361702 chr7:150065534 REPIN1 0.55 7.6 0.38 2.78e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs9296092 0.560 rs9469506 chr6:33527897 A/G cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7953508 0.750 rs7310512 chr12:93976703 C/T cg18151635 chr12:93972918 NA -0.44 -6.89 -0.35 2.74e-11 Pubertal anthropometrics; LIHC cis rs4728302 0.869 rs10954434 chr7:133597864 A/G cg10665199 chr7:133106180 EXOC4 0.38 6.64 0.34 1.21e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7572733 0.555 rs13395030 chr2:198750806 A/G cg03934865 chr2:198174659 NA 0.45 6.49 0.33 2.96e-10 Dermatomyositis; LIHC cis rs57590327 0.503 rs6776737 chr3:81513729 T/C cg07356753 chr3:81810745 GBE1 0.46 6.84 0.35 3.7e-11 Extraversion; LIHC cis rs11779988 0.501 rs3760 chr8:17886345 T/C cg01800426 chr8:17659068 MTUS1 -0.4 -6.18 -0.32 1.78e-9 Breast cancer; LIHC cis rs11763147 1 rs11763147 chr7:65326821 C/T cg11764359 chr7:65958608 NA -0.7 -9.44 -0.45 6.08e-19 Corneal structure; LIHC cis rs1178968 0.901 rs1178953 chr7:72781277 A/G cg25889504 chr7:72793014 NA 0.36 5.74 0.3 2.08e-8 Triglyceride levels; LIHC cis rs727505 1.000 rs28702851 chr7:124442991 G/A cg23710748 chr7:124431027 NA -0.35 -6.13 -0.31 2.42e-9 Lewy body disease; LIHC cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg11062466 chr8:58055876 NA 0.47 6.54 0.33 2.24e-10 Developmental language disorder (linguistic errors); LIHC cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg18867708 chr6:26865862 GUSBL1 0.41 6.15 0.32 2.12e-9 Intelligence (multi-trait analysis); LIHC cis rs7249142 0.597 rs759999 chr19:19281207 A/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.37 -6.16 -0.32 2.09e-9 IgG glycosylation; LIHC cis rs7100689 0.646 rs10466235 chr10:82149655 C/T cg01528321 chr10:82214614 TSPAN14 -0.61 -9.4 -0.45 7.83e-19 Post bronchodilator FEV1; LIHC cis rs6754311 0.638 rs2322659 chr2:136555659 A/G cg07305463 chr2:136567211 LCT 0.34 6.08 0.31 3.14e-9 Mosquito bite size; LIHC cis rs5769765 0.955 rs7511159 chr22:50307896 A/G cg26441486 chr22:50317300 CRELD2 0.36 6.48 0.33 3.14e-10 Schizophrenia; LIHC cis rs9457247 0.565 rs2038580 chr6:167456490 A/T cg12798992 chr6:167411361 FGFR1OP 0.47 6.86 0.35 3.19e-11 Crohn's disease; LIHC cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg18357526 chr6:26021779 HIST1H4A -0.51 -6.86 -0.35 3.32e-11 Blood metabolite levels; LIHC cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg16325326 chr1:53192061 ZYG11B 0.42 6.97 0.35 1.65e-11 Monocyte count; LIHC cis rs7635838 0.892 rs9814907 chr3:11438645 G/A cg00170343 chr3:11313890 ATG7 0.45 7.04 0.36 1.08e-11 HDL cholesterol; LIHC cis rs7412746 0.634 rs72704658 chr1:150833010 T/C cg17724175 chr1:150552817 MCL1 0.47 9.08 0.44 9e-18 Melanoma; LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs9818758 0.607 rs9880088 chr3:49178990 G/A cg06212747 chr3:49208901 KLHDC8B -0.64 -5.75 -0.3 1.96e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11105298 0.891 rs10858854 chr12:89835728 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.38 -0.37 1.24e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2279817 0.863 rs13376020 chr1:18016402 A/G cg21791023 chr1:18019539 ARHGEF10L -0.68 -7.99 -0.4 2.06e-14 Neuroticism; LIHC cis rs61041384 0.661 rs77015199 chr12:123681637 G/C cg00376283 chr12:123451042 ABCB9 -0.55 -6.14 -0.32 2.28e-9 Schizophrenia; LIHC trans rs6600671 1.000 rs1856572 chr1:121169579 A/C cg09829573 chr1:144692074 NBPF9 -0.42 -7.64 -0.38 2.17e-13 Hip geometry; LIHC cis rs748404 0.631 rs6493083 chr15:43637985 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.51 8.1 0.4 9.81e-15 Lung cancer; LIHC cis rs9309473 0.948 rs2421577 chr2:73840998 G/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.93 -0.35 2.07e-11 Metabolite levels; LIHC cis rs611744 0.967 rs681099 chr8:109218892 T/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.63e-17 Dupuytren's disease; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg02951883 chr7:2050386 MAD1L1 -0.85 -15.49 -0.64 2.29e-41 Bipolar disorder and schizophrenia; LIHC cis rs7937682 0.924 rs10891286 chr11:111532691 C/G cg09085632 chr11:111637200 PPP2R1B -1.04 -13.22 -0.58 1.56e-32 Primary sclerosing cholangitis; LIHC cis rs55665837 0.540 rs12416696 chr11:14790889 G/A cg25251204 chr11:14927456 NA 0.41 5.84 0.3 1.21e-8 Vitamin D levels; LIHC cis rs801193 1.000 rs3800812 chr7:66223461 T/C cg18876405 chr7:65276391 NA 0.42 7.35 0.37 1.52e-12 Aortic root size; LIHC trans rs208520 0.802 rs208499 chr6:66932146 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.11 -0.4 9.46e-15 Exhaled nitric oxide output; LIHC cis rs15676 0.783 rs4489410 chr9:131591649 A/C cg00228799 chr9:131580591 ENDOG -0.46 -6.77 -0.34 5.77e-11 Blood metabolite levels; LIHC trans rs1814175 0.817 rs4881645 chr11:49791168 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.51 -0.79 2.04e-73 Height; LIHC cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg13395646 chr4:1353034 KIAA1530 -0.43 -6.23 -0.32 1.34e-9 Longevity; LIHC cis rs875971 0.862 rs10274883 chr7:66116091 C/T cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs34375054 0.525 rs7133864 chr12:125606180 C/T cg25124228 chr12:125621409 AACS -0.5 -9.36 -0.45 1.12e-18 Post bronchodilator FEV1/FVC ratio; LIHC cis rs10791097 0.694 rs7926167 chr11:130745045 T/C cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1419980 0.643 rs11054919 chr12:7778109 C/G cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC trans rs6582630 0.500 rs35251810 chr12:38577666 T/C cg05848834 chr11:43543746 NA -0.3 -6.11 -0.31 2.64e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs79149102 0.579 rs12594117 chr15:75323648 C/G cg09165964 chr15:75287851 SCAMP5 -0.6 -8.17 -0.4 5.84e-15 Lung cancer; LIHC cis rs2832191 0.791 rs7283853 chr21:30498515 G/A cg24692254 chr21:30365293 RNF160 -0.59 -10.27 -0.49 9.66e-22 Dental caries; LIHC cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.44e-8 Alzheimer's disease; LIHC cis rs7786877 0.521 rs2293767 chr7:100361675 A/G cg20848291 chr7:100343083 ZAN 0.34 5.84 0.3 1.25e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04053862 chr2:179345017 MIR548N;PLEKHA3 0.43 6.12 0.31 2.55e-9 Lung function (FEV1/FVC); LIHC cis rs1005277 0.579 rs2474569 chr10:38383491 C/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs6141769 0.518 rs2377665 chr20:31309054 T/C cg13636640 chr20:31349939 DNMT3B -0.31 -5.73 -0.3 2.15e-8 Subjective well-being; LIHC cis rs1707322 1.000 rs4660335 chr1:46474718 C/T cg06784218 chr1:46089804 CCDC17 0.38 6.71 0.34 8.11e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9291683 0.588 rs17247314 chr4:10004743 C/G cg11266682 chr4:10021025 SLC2A9 0.31 6.52 0.33 2.48e-10 Bone mineral density; LIHC trans rs561341 0.830 rs7218801 chr17:30217778 A/G cg20587970 chr11:113659929 NA 0.71 8.23 0.41 3.93e-15 Hip circumference adjusted for BMI; LIHC cis rs7537052 0.669 rs2296263 chr1:36641729 C/T cg24686825 chr1:36642396 MAP7D1 -0.46 -8.52 -0.42 5.03e-16 Schizophrenia; LIHC cis rs35306767 0.859 rs11817793 chr10:878895 C/T cg26597838 chr10:835615 NA 1.15 14.33 0.61 8.58e-37 Eosinophil percentage of granulocytes; LIHC cis rs4788570 0.566 rs2052873 chr16:71505303 C/T cg06353428 chr16:71660113 MARVELD3 -0.87 -8.03 -0.4 1.62e-14 Intelligence (multi-trait analysis); LIHC cis rs16828019 0.777 rs10489521 chr1:41508490 C/T cg03962019 chr1:41807865 NA 0.49 7.03 0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg00656387 chr3:40428638 ENTPD3 0.43 6.98 0.35 1.58e-11 Renal cell carcinoma; LIHC cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg22633049 chr21:46681294 NA -0.37 -6.36 -0.33 6.37e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs748404 0.660 rs542898 chr15:43719392 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.15 0.36 5.42e-12 Lung cancer; LIHC cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg00149659 chr3:10157352 C3orf10 0.66 6.79 0.34 5.09e-11 Alzheimer's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06759328 chr11:76572255 ACER3 0.47 6.72 0.34 7.41e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs9929218 0.953 rs12930910 chr16:68762520 A/G cg01231543 chr16:68741748 NA 0.4 6.3 0.32 9.42e-10 Colorectal cancer; LIHC cis rs1552244 0.554 rs28667821 chr3:10050767 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.75 0.39 1.05e-13 Alzheimer's disease; LIHC cis rs2153535 0.580 rs6902001 chr6:8477055 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC trans rs1347297 0.526 rs10201175 chr2:179265348 C/T cg14011486 chr1:26737247 LIN28 0.56 8.11 0.4 9.25e-15 Alzheimer disease and age of onset; LIHC cis rs4927850 1.000 rs4927848 chr3:195738406 A/G cg01181863 chr3:195395398 SDHAP2 -0.63 -8.0 -0.4 1.98e-14 Pancreatic cancer; LIHC cis rs4924590 0.531 rs12913835 chr15:42227869 C/T cg20935245 chr15:42234343 EHD4 0.39 7.21 0.36 3.68e-12 Lymphocyte percentage of white cells;Sum basophil neutrophil counts;Granulocyte count; LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg12419862 chr22:24373484 LOC391322 -0.66 -9.73 -0.47 6.43e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7552404 0.727 rs5745427 chr1:76332637 C/A cg10523679 chr1:76189770 ACADM -0.55 -6.95 -0.35 1.82e-11 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2243480 1.000 rs4548056 chr7:65298873 A/G cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs703842 1.000 rs703842 chr12:58162739 C/T cg18357645 chr12:58087776 OS9 0.42 6.69 0.34 9.06e-11 Multiple sclerosis; LIHC cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1008375 1.000 rs11727312 chr4:17669185 C/T cg02297831 chr4:17616191 MED28 0.4 6.46 0.33 3.59e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs1994135 0.647 rs66542958 chr12:33695385 T/G cg26384229 chr12:38710491 ALG10B 0.49 6.57 0.33 1.85e-10 Resting heart rate; LIHC cis rs12791968 0.659 rs12808379 chr11:45009273 C/G cg11846598 chr11:44996168 LOC221122 -0.4 -6.54 -0.33 2.31e-10 Inhibitory control; LIHC cis rs12701220 0.857 rs1057558 chr7:1062366 A/G cg00990874 chr7:1149470 C7orf50 -0.69 -9.68 -0.46 9.52e-20 Bronchopulmonary dysplasia; LIHC cis rs4888262 0.545 rs4888270 chr16:74698576 A/G cg01733217 chr16:74700730 RFWD3 0.86 17.99 0.7 2.19e-51 Testicular germ cell tumor; LIHC cis rs1385374 0.858 rs959989 chr12:129292708 A/T cg09035930 chr12:129282057 SLC15A4 -0.5 -5.89 -0.3 9.38e-9 Systemic lupus erythematosus; LIHC cis rs9325144 0.555 rs11183215 chr12:38693127 G/A cg26384229 chr12:38710491 ALG10B -0.58 -7.95 -0.39 2.81e-14 Morning vs. evening chronotype; LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs6456156 0.846 rs9364891 chr6:167516319 C/T cg23791538 chr6:167370224 RNASET2 0.41 6.51 0.33 2.75e-10 Primary biliary cholangitis; LIHC cis rs918629 0.530 rs10070197 chr5:95241868 T/C cg10483112 chr5:95245456 ELL2 -0.38 -7.15 -0.36 5.26e-12 IgG glycosylation; LIHC cis rs763121 0.651 rs738249 chr22:39037979 T/C cg14440974 chr22:39074834 NA -0.42 -6.65 -0.34 1.15e-10 Menopause (age at onset); LIHC cis rs1003719 0.788 rs9977602 chr21:38450650 G/T cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 6.97e-29 Eye color traits; LIHC trans rs35110281 0.748 rs9981460 chr21:45030965 T/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.21e-9 Mean corpuscular volume; LIHC cis rs950169 0.922 rs11633075 chr15:85113972 C/A cg12863693 chr15:85201151 NMB 0.45 6.23 0.32 1.38e-9 Schizophrenia; LIHC cis rs4975616 0.869 rs421284 chr5:1325590 T/C cg06550200 chr5:1325588 CLPTM1L -0.68 -10.95 -0.51 4.1e-24 Lung cancer; LIHC cis rs12711979 0.765 rs13028529 chr2:3825467 C/T cg17052675 chr2:3827356 NA -0.47 -8.13 -0.4 7.91e-15 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs7178375 1.000 rs1474381 chr15:31214991 T/C cg04373760 chr16:53404718 NA 0.59 7.7 0.38 1.48e-13 Hypertriglyceridemia; LIHC cis rs9811920 0.609 rs793467 chr3:99539664 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.47 -6.43 -0.33 4.37e-10 Axial length; LIHC cis rs1494373 0.504 rs796486 chr1:220885612 C/A cg06786860 chr1:220876396 NA -0.48 -7.1 -0.36 7.1e-12 Response to antipsychotic therapy (extrapyramidal side effects); LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg17786042 chr8:19125368 NA -0.46 -6.24 -0.32 1.26e-9 Monocyte count; LIHC cis rs8180040 0.967 rs807935 chr3:47321669 A/G cg02527881 chr3:46936655 PTH1R -0.3 -5.89 -0.3 9.21e-9 Colorectal cancer; LIHC cis rs738321 0.794 rs6001026 chr22:38545363 C/T cg25457927 chr22:38595422 NA -0.35 -7.85 -0.39 5.27e-14 Breast cancer; LIHC cis rs754466 0.874 rs10430531 chr10:79660125 T/C cg17075019 chr10:79541650 NA -0.64 -8.66 -0.42 1.94e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg11062466 chr8:58055876 NA 0.48 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs9611519 0.929 rs12484971 chr22:41439304 A/T cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.13e-14 Neuroticism; LIHC cis rs61677309 0.638 rs57461652 chr11:118146197 C/A cg06090739 chr11:118230722 UBE4A 0.32 6.04 0.31 3.98e-9 Lung cancer in ever smokers; LIHC cis rs9733 0.596 rs34140753 chr1:150642583 T/C cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04904834 chr1:179851103 TOR1AIP1 0.46 7.17 0.36 4.73e-12 Cognitive function; LIHC cis rs986417 1.000 rs1254303 chr14:60886301 A/G cg27398547 chr14:60952738 C14orf39 -0.77 -8.88 -0.43 3.77e-17 Gut microbiota (bacterial taxa); LIHC cis rs2777491 0.874 rs28716108 chr15:41655523 G/C cg18705301 chr15:41695430 NDUFAF1 -0.62 -9.45 -0.46 5.48e-19 Ulcerative colitis; LIHC cis rs7000551 0.619 rs2443506 chr8:22373383 T/C cg12081754 chr8:22256438 SLC39A14 0.41 6.54 0.33 2.27e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2180341 0.960 rs9398839 chr6:127665863 G/A cg27446573 chr6:127587934 RNF146 1.06 16.62 0.67 6.67e-46 Breast cancer; LIHC cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.49 -0.56 9.36e-30 Alzheimer's disease; LIHC cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg13409248 chr3:40428643 ENTPD3 0.43 7.21 0.36 3.51e-12 Renal cell carcinoma; LIHC cis rs4891159 0.548 rs690423 chr18:74117984 G/A cg24786174 chr18:74118243 ZNF516 0.86 17.67 0.69 4.33e-50 Longevity; LIHC cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg06481639 chr22:41940642 POLR3H -0.72 -6.74 -0.34 6.5500000000000006e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs780096 0.587 rs10205219 chr2:27568565 T/C cg21747090 chr2:27597821 SNX17 -0.47 -7.19 -0.36 4.15e-12 Total body bone mineral density; LIHC cis rs4699052 0.507 rs6533085 chr4:104281586 A/T cg16532752 chr4:104119610 CENPE -0.44 -6.08 -0.31 3.18e-9 Testicular germ cell tumor; LIHC cis rs2242116 0.734 rs4683294 chr3:46979013 C/G cg16586182 chr3:47516702 SCAP 0.35 5.82 0.3 1.34e-8 Birth weight; LIHC cis rs1707322 0.685 rs56177313 chr1:46225806 A/C cg03146154 chr1:46216737 IPP 0.57 9.64 0.46 1.26e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg07092213 chr7:1199455 ZFAND2A -0.41 -6.11 -0.31 2.79e-9 Longevity;Endometriosis; LIHC cis rs56104184 0.723 rs116909499 chr19:49407733 C/T cg15549821 chr19:49342101 PLEKHA4 -0.65 -6.17 -0.32 1.9e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17939001 chr1:197871836 C1orf53 -0.46 -6.63 -0.34 1.32e-10 Alopecia areata; LIHC cis rs1000083 0.748 rs1528592 chr5:96659728 T/C ch.5.96698337R chr5:96672581 NA 0.95 7.25 0.36 2.87e-12 Cisplatin-induced ototoxicity; LIHC cis rs950169 0.580 rs36126054 chr15:85177723 T/G cg17507749 chr15:85114479 UBE2QP1 0.69 7.89 0.39 4.08e-14 Schizophrenia; LIHC cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg23205692 chr1:25664452 TMEM50A -0.39 -6.34 -0.32 7.28e-10 Erythrocyte sedimentation rate; LIHC cis rs2404602 0.532 rs284892 chr15:76721037 A/G cg23625390 chr15:77176239 SCAPER 0.39 6.53 0.33 2.38e-10 Blood metabolite levels; LIHC cis rs2243480 1.000 rs13237037 chr7:65997882 T/C cg12463550 chr7:65579703 CRCP 0.67 6.9 0.35 2.49e-11 Diabetic kidney disease; LIHC cis rs9910055 0.571 rs10208 chr17:42300278 C/T cg08499158 chr17:42289980 UBTF -0.52 -8.92 -0.43 2.85e-17 Total body bone mineral density; LIHC cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg02951883 chr7:2050386 MAD1L1 -0.62 -9.25 -0.45 2.55e-18 Bipolar disorder and schizophrenia; LIHC cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg11645453 chr3:52864694 ITIH4 0.21 5.75 0.3 2.01e-8 Intelligence (multi-trait analysis); LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg19500098 chr13:21900506 NA 0.36 5.94 0.31 6.86e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9513627 1.000 rs7334274 chr13:100120801 G/A cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg12386194 chr3:101231763 SENP7 0.46 6.76 0.34 6.11e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs34779708 0.966 rs11010135 chr10:35518063 A/G cg03585969 chr10:35415529 CREM 0.88 13.0 0.58 1.12e-31 Inflammatory bowel disease;Crohn's disease; LIHC trans rs6952808 0.895 rs4513875 chr7:1928159 C/T cg04565464 chr8:145669602 NFKBIL2 0.38 6.12 0.31 2.52e-9 Bipolar disorder and schizophrenia; LIHC cis rs11626933 1.000 rs7146724 chr14:90766092 C/T cg04374321 chr14:90722782 PSMC1 0.48 6.64 0.34 1.23e-10 Gut microbiota (bacterial taxa); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg27356188 chr5:637386 CEP72 0.43 6.37 0.33 6.13e-10 Migraine with aura; LIHC cis rs3796352 1.000 rs34933390 chr3:53006265 T/G cg07884673 chr3:53033167 SFMBT1 0.9 6.59 0.34 1.63e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs4665809 0.941 rs11126336 chr2:26245931 C/T cg04944784 chr2:26401820 FAM59B -0.67 -8.44 -0.42 8.98e-16 Gut microbiome composition (summer); LIHC cis rs769267 0.930 rs7254748 chr19:19397479 A/C cg03709012 chr19:19516395 GATAD2A 0.94 15.76 0.65 1.93e-42 Tonsillectomy; LIHC cis rs4474465 0.850 rs10793323 chr11:78244170 C/T cg27205649 chr11:78285834 NARS2 0.39 6.15 0.32 2.14e-9 Alzheimer's disease (survival time); LIHC cis rs9633740 0.947 rs7096909 chr10:82284512 A/T cg01528321 chr10:82214614 TSPAN14 -0.92 -11.32 -0.52 1.91e-25 Post bronchodilator FEV1; LIHC cis rs950776 0.752 rs62010328 chr15:78894971 C/T cg06917634 chr15:78832804 PSMA4 0.63 8.57 0.42 3.56e-16 Sudden cardiac arrest; LIHC cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg11890956 chr21:40555474 PSMG1 -0.52 -8.41 -0.41 1.16e-15 Cognitive function; LIHC cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg22800045 chr5:56110881 MAP3K1 0.68 8.73 0.43 1.18e-16 Initial pursuit acceleration; LIHC cis rs858239 0.600 rs7799422 chr7:23128413 G/A cg23682824 chr7:23144976 KLHL7 0.43 6.48 0.33 3.18e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs5769765 1.000 rs1033665 chr22:50252127 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -9.17 -0.44 4.43e-18 Schizophrenia; LIHC cis rs798554 0.759 rs1182189 chr7:2869522 G/A cg19717773 chr7:2847554 GNA12 -0.44 -6.51 -0.33 2.75e-10 Height; LIHC trans rs3780486 0.505 rs10117038 chr9:33122626 T/C cg20290983 chr6:43655470 MRPS18A 0.94 19.94 0.73 3.03e-59 IgG glycosylation; LIHC trans rs10411161 0.702 rs7251755 chr19:52388948 G/A cg22319618 chr22:45562946 NUP50 -0.62 -8.49 -0.42 6.32e-16 Breast cancer; LIHC cis rs10174077 0.874 rs11892439 chr2:152469858 T/A cg06191203 chr2:152266755 RIF1 -0.4 -6.97 -0.35 1.68e-11 Squamous cell lung carcinoma; LIHC cis rs72772090 0.908 rs11750510 chr5:96042095 T/C cg17330273 chr5:96107758 CAST;ERAP1 -0.57 -6.52 -0.33 2.49e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6840360 0.593 rs6857073 chr4:152689274 A/G cg22705602 chr4:152727874 NA 0.34 6.76 0.34 5.89e-11 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.673 rs55904046 chr17:29215391 G/A cg14067834 chr17:29058358 SUZ12P 0.67 6.48 0.33 3.26e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs876084 0.505 rs4336644 chr8:121136128 G/C cg06265175 chr8:121136014 COL14A1 0.42 6.58 0.34 1.79e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1580019 0.587 rs6951955 chr7:32548761 A/T cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.16 0.44 4.82e-18 Cognitive ability; LIHC cis rs13161895 0.941 rs3797764 chr5:179439345 A/G cg06664874 chr5:179499304 RNF130 -0.58 -7.12 -0.36 6.37e-12 LDL cholesterol; LIHC cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg02290350 chr8:58132656 NA 0.41 8.46 0.42 7.71e-16 Developmental language disorder (linguistic errors); LIHC cis rs427394 0.659 rs274674 chr5:6755460 C/T cg10857441 chr5:6722123 POLS -0.4 -6.67 -0.34 1.01e-10 Menopause (age at onset); LIHC cis rs67460515 0.892 rs4856756 chr3:160999414 G/A cg03342759 chr3:160939853 NMD3 -0.66 -10.13 -0.48 2.84e-21 Parkinson's disease; LIHC cis rs1712517 0.771 rs59744322 chr10:105146692 G/T cg05636881 chr10:105038444 INA 0.49 7.69 0.38 1.58e-13 Migraine; LIHC cis rs1008375 0.900 rs1003413 chr4:17582442 C/T cg02297831 chr4:17616191 MED28 -0.42 -5.81 -0.3 1.43e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2204008 0.805 rs7296063 chr12:37964775 T/G cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs507080 0.883 rs527475 chr11:118563239 G/A cg04173919 chr11:118528438 PHLDB1 0.35 6.55 0.33 2.07e-10 Serum metabolite levels; LIHC cis rs12477438 0.798 rs10196680 chr2:99628617 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.92 -0.65 4.52e-43 Chronic sinus infection; LIHC cis rs3789045 0.779 rs12043569 chr1:204560004 C/G cg17419461 chr1:204415978 PIK3C2B -0.39 -6.23 -0.32 1.39e-9 Educational attainment (college completion); LIHC cis rs77861329 0.920 rs9860982 chr3:52096432 T/C cg08692210 chr3:52188851 WDR51A 0.84 7.93 0.39 3.05e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs1983891 1.000 rs1983891 chr6:41536427 A/G cg20194872 chr6:41519635 FOXP4 -0.39 -6.26 -0.32 1.18e-9 Prostate cancer; LIHC cis rs2115630 1.000 rs11854313 chr15:85304048 G/C cg12501888 chr15:85177176 SCAND2 -0.49 -7.63 -0.38 2.4e-13 P wave terminal force; LIHC cis rs473651 0.904 rs501333 chr2:239336045 G/A cg21699342 chr2:239360505 ASB1 0.36 6.94 0.35 1.98e-11 Multiple system atrophy; LIHC cis rs7937682 0.575 rs34888817 chr11:111756455 C/T cg09085632 chr11:111637200 PPP2R1B 0.96 13.89 0.6 4.46e-35 Primary sclerosing cholangitis; LIHC cis rs10876993 0.928 rs1689594 chr12:58057156 T/C cg18357645 chr12:58087776 OS9 0.51 8.44 0.42 9.08e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs1801251 1.000 rs7606090 chr2:233606740 T/C cg08000102 chr2:233561755 GIGYF2 0.75 11.3 0.52 2.24e-25 Coronary artery disease; LIHC cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.19 -0.44 4.04e-18 Bipolar disorder; LIHC cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.94 -0.31 7.07e-9 Colorectal cancer; LIHC cis rs13161895 1.000 rs4129403 chr5:179476610 A/G cg06664874 chr5:179499304 RNF130 0.65 7.92 0.39 3.46e-14 LDL cholesterol; LIHC cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg27572855 chr1:25598939 RHD -0.38 -8.13 -0.4 7.79e-15 Erythrocyte sedimentation rate; LIHC cis rs6933660 0.760 rs3806982 chr6:151774916 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.57 -8.67 -0.42 1.79e-16 Menarche (age at onset); LIHC cis rs4555082 0.834 rs28489970 chr14:105748862 T/C cg13114125 chr14:105738426 BRF1 -0.74 -9.78 -0.47 4.42e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs7534824 0.625 rs12568338 chr1:101500622 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.76 7.03 0.36 1.1e-11 Refractive astigmatism; LIHC cis rs17125944 0.656 rs74825460 chr14:53390015 C/T cg00686598 chr14:53173677 PSMC6 0.76 8.23 0.41 3.85e-15 Alzheimer's disease (late onset); LIHC cis rs4925386 0.840 rs6143036 chr20:60921721 C/A cg24112000 chr20:60950667 NA -0.45 -5.98 -0.31 5.49e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs3768617 0.510 rs4651145 chr1:183098900 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg22105103 chr4:187893119 NA 0.33 8.09 0.4 1.05e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg11070056 chr1:107600091 PRMT6 -0.71 -12.16 -0.55 1.64e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11122272 0.638 rs2739514 chr1:231514806 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.73 -0.5 2.5e-23 Hemoglobin concentration; LIHC cis rs10503871 0.657 rs13248936 chr8:30316162 C/T cg26383811 chr8:30366931 RBPMS -0.42 -7.36 -0.37 1.36e-12 Metabolite levels (X-11787); LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.45 7.69 0.38 1.53e-13 Height; LIHC cis rs11588062 0.703 rs11589812 chr1:46858748 C/T cg23431851 chr1:46668822 C1orf190;POMGNT1 0.46 7.16 0.36 4.97e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs34779708 0.966 rs878264 chr10:35440581 T/C cg03585969 chr10:35415529 CREM 0.85 12.9 0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg05368731 chr17:41323189 NBR1 0.72 12.05 0.55 4.2e-28 Menopause (age at onset); LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.4 8.65 0.42 1.97e-16 Calcium levels; LIHC cis rs7772486 0.790 rs2814880 chr6:146208937 T/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.85 -0.3 1.16e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.730 rs78971550 chr4:120281041 C/T cg25214090 chr10:38739885 LOC399744 0.5 7.68 0.38 1.7e-13 Corneal astigmatism; LIHC cis rs7223966 0.960 rs113155878 chr17:61706560 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.75 0.34 6.22e-11 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs8073060 0.586 rs72829922 chr17:34044809 G/A cg19694781 chr19:47549865 TMEM160 1.22 12.75 0.57 9.9e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2963155 0.518 rs852978 chr5:142690596 T/C cg17617527 chr5:142782415 NR3C1 0.9 10.56 0.5 9.71e-23 Breast cancer; LIHC cis rs7587476 1.000 rs2121285 chr2:215656168 C/G cg04530015 chr2:215796436 ABCA12 0.4 6.4 0.33 5e-10 Neuroblastoma; LIHC cis rs3736485 0.932 rs10519313 chr15:51915812 C/T cg08986416 chr15:51914746 DMXL2 -0.47 -7.01 -0.35 1.28e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs593982 1.000 rs576663 chr11:65498942 G/T cg08755490 chr11:65554678 OVOL1 0.55 8.56 0.42 3.82e-16 Atopic dermatitis; LIHC cis rs2075371 0.933 rs1868785 chr7:133945855 G/C cg11752832 chr7:134001865 SLC35B4 0.51 7.73 0.39 1.18e-13 Mean platelet volume; LIHC cis rs1055129 0.560 rs9891076 chr17:73911715 C/T cg08125733 chr17:73851984 WBP2 0.56 8.61 0.42 2.63e-16 White matter hyperintensity burden; LIHC cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg07636037 chr3:49044803 WDR6 0.77 13.01 0.58 1.02e-31 Menarche (age at onset); LIHC cis rs4076764 0.958 rs6688997 chr1:163411562 G/A cg24596788 chr1:163392923 NA -0.24 -7.5 -0.38 5.7e-13 Motion sickness; LIHC cis rs9457247 1.000 rs932644 chr6:167404187 A/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.02 -0.51 2.23e-24 Crohn's disease; LIHC cis rs1707322 0.716 rs28370457 chr1:46172062 C/T cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs8103278 0.507 rs2041975 chr19:46238555 T/C cg12641515 chr19:46296257 DMWD 0.46 7.12 0.36 6.56e-12 Coronary artery disease; LIHC cis rs7264396 0.790 rs1040695 chr20:34244829 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -9.64 -0.46 1.32e-19 Total cholesterol levels; LIHC cis rs909002 1.000 rs909002 chr1:32139635 C/T cg13919466 chr1:32135498 COL16A1 -0.38 -7.65 -0.38 2.09e-13 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs3755782 chr3:10029305 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.71 9.7 0.46 7.92e-20 Alzheimer's disease; LIHC cis rs4934494 0.768 rs12776306 chr10:91436057 T/A cg19698084 chr10:91461284 KIF20B -0.49 -6.49 -0.33 2.93e-10 Red blood cell count; LIHC cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.82 8.61 0.42 2.63e-16 Platelet count; LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg06656553 chr16:89960601 TCF25 -0.48 -6.28 -0.32 1.02e-9 Skin colour saturation; LIHC cis rs1728785 1.000 rs1749792 chr16:68569440 T/G cg02972257 chr16:68554789 NA -0.52 -6.11 -0.31 2.79e-9 Ulcerative colitis; LIHC cis rs11098499 0.909 rs28581362 chr4:120283548 T/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs11711311 1.000 rs6792447 chr3:113508335 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.85 -0.35 3.37e-11 IgG glycosylation; LIHC cis rs6912958 0.781 rs4334949 chr6:88290150 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC cis rs9303401 0.659 rs714959 chr17:56628601 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.55 5.18e-28 Cognitive test performance; LIHC cis rs73001065 0.591 rs2285626 chr19:19467545 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.52 6.2 0.32 1.66e-9 LDL cholesterol; LIHC cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.2e-8 Vitiligo; LIHC cis rs34172651 0.917 rs7202252 chr16:24741686 T/C cg04756594 chr16:24857601 SLC5A11 -0.49 -7.66 -0.38 1.95e-13 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg02290350 chr8:58132656 NA 0.51 11.04 0.51 1.9e-24 Developmental language disorder (linguistic errors); LIHC cis rs17253792 0.545 rs12893061 chr14:56016097 A/T cg01858014 chr14:56050164 KTN1 -0.62 -5.89 -0.3 9.46e-9 Putamen volume; LIHC cis rs2180341 0.960 rs7756884 chr6:127684018 A/G cg27446573 chr6:127587934 RNF146 1.06 16.75 0.67 2.08e-46 Breast cancer; LIHC cis rs6831352 0.918 rs2602895 chr4:100045840 C/T cg12011299 chr4:100065546 ADH4 0.61 10.36 0.49 4.77e-22 Alcohol dependence; LIHC cis rs11628318 0.515 rs11627756 chr14:103096606 C/T cg12046867 chr14:103022105 NA -0.37 -5.72 -0.3 2.28e-8 Platelet count; LIHC cis rs6565681 1.000 rs6565681 chr17:78348494 A/G cg15383979 chr17:78362278 RNF213;LOC100294362 -0.52 -7.42 -0.37 9.22e-13 Moyamoya disease; LIHC cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg15691649 chr6:25882328 NA -0.77 -11.31 -0.52 2.06e-25 Blood metabolite levels; LIHC cis rs10504229 1.000 rs72652906 chr8:58188360 C/A cg20607798 chr8:58055168 NA 0.46 5.85 0.3 1.14e-8 Developmental language disorder (linguistic errors); LIHC cis rs13118159 0.801 rs1128427 chr4:1330759 T/C cg16405210 chr4:1374714 KIAA1530 -0.51 -7.31 -0.37 1.96e-12 Longevity; LIHC trans rs875971 0.638 rs35986979 chr7:66088990 G/A cg26939375 chr7:64535504 NA -0.43 -6.87 -0.35 3.05e-11 Aortic root size; LIHC cis rs7572733 0.534 rs1435568 chr2:198762879 T/C cg00792783 chr2:198669748 PLCL1 0.48 6.98 0.35 1.57e-11 Dermatomyositis; LIHC cis rs11628318 0.614 rs10782496 chr14:103079725 C/G cg23461800 chr14:103021989 NA -0.38 -5.84 -0.3 1.23e-8 Platelet count; LIHC cis rs12824058 0.831 rs7485200 chr12:130811641 C/T cg26677194 chr12:130822605 PIWIL1 0.53 7.43 0.37 8.59e-13 Menopause (age at onset); LIHC cis rs7666738 0.830 rs35822567 chr4:98654138 G/A cg05340658 chr4:99064831 C4orf37 0.63 11.07 0.51 1.56e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs13161895 0.938 rs594202 chr5:179417335 C/T cg02702477 chr5:179499311 RNF130 0.75 10.32 0.49 6.59e-22 LDL cholesterol; LIHC cis rs921968 0.541 rs6717433 chr2:219375711 G/C cg02176678 chr2:219576539 TTLL4 -0.57 -7.85 -0.39 5.45e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs58688157 0.705 rs12795572 chr11:590999 G/A cg16486109 chr11:613632 IRF7 0.58 6.23 0.32 1.36e-9 Systemic lupus erythematosus; LIHC cis rs11122272 0.735 rs10489611 chr1:231517854 A/T cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs7552404 1.000 rs28602663 chr1:76235355 C/T cg10523679 chr1:76189770 ACADM 0.65 8.69 0.43 1.56e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs60871478 0.898 rs35928069 chr7:823067 G/C cg05535760 chr7:792225 HEATR2 0.77 10.68 0.5 3.47e-23 Cerebrospinal P-tau181p levels; LIHC cis rs796364 0.616 rs1523818 chr2:200684704 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.16 0.32 2.03e-9 Schizophrenia; LIHC cis rs9790314 0.905 rs4856739 chr3:160986710 A/C cg03342759 chr3:160939853 NMD3 -0.74 -9.61 -0.46 1.59e-19 Morning vs. evening chronotype; LIHC cis rs898097 0.528 rs2243523 chr17:80680449 G/T cg05255149 chr17:80675120 FN3KRP -0.42 -6.26 -0.32 1.15e-9 Breast cancer; LIHC cis rs13191362 0.810 rs13200053 chr6:163011443 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.83 0.3 1.26e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9303401 0.527 rs7224468 chr17:56749943 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.93 12.04 0.55 4.45e-28 Cognitive test performance; LIHC cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg00750074 chr16:89608354 SPG7 -0.53 -8.62 -0.42 2.58e-16 Multiple myeloma (IgH translocation); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg27470307 chr11:61106785 DAK 0.33 6.04 0.31 4.08e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs80282103 0.867 rs7075830 chr10:1091650 G/C cg20335179 chr10:1068567 C10orf110;IDI2 -0.56 -5.89 -0.3 9.32e-9 Glomerular filtration rate (creatinine); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22994272 chr14:104346241 NA 0.42 7.09 0.36 7.76e-12 Cognitive function; LIHC cis rs9916302 0.904 rs13341996 chr17:37536862 C/T cg03013999 chr17:37608204 MED1 -0.36 -5.91 -0.3 8.4e-9 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.763 rs2513277 chr11:68360887 T/G cg16797656 chr11:68205561 LRP5 0.5 8.85 0.43 4.7e-17 Total body bone mineral density; LIHC cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.59 -8.86 -0.43 4.51e-17 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19812495 chr5:71616193 MRPS27;PTCD2 0.47 6.59 0.34 1.7e-10 Lung function (FEV1/FVC); LIHC cis rs903552 1.000 rs12907048 chr15:102003873 G/T cg19295451 chr15:102010161 PCSK6 -0.44 -6.08 -0.31 3.17e-9 Diabetic kidney disease; LIHC cis rs7116495 0.609 rs2885661 chr11:71588331 C/G cg10381502 chr11:71823885 C11orf51 0.89 7.3 0.37 2.07e-12 Severe influenza A (H1N1) infection; LIHC cis rs600806 0.850 rs10858092 chr1:109943893 A/G cg02415029 chr1:110025642 ATXN7L2 0.47 6.0 0.31 5.01e-9 Intelligence (multi-trait analysis); LIHC cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg14983838 chr19:29218262 NA 0.48 7.49 0.38 5.79e-13 Methadone dose in opioid dependence; LIHC cis rs2732480 0.557 rs2732484 chr12:48737245 A/C cg21466736 chr12:48725269 NA -0.72 -11.03 -0.51 2.11e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs6701037 0.625 rs67332874 chr1:175128537 G/A cg00958927 chr1:175162553 KIAA0040 -0.4 -6.55 -0.33 2.08e-10 Alcohol dependence; LIHC cis rs172166 0.637 rs1233691 chr6:28153897 T/G cg16479474 chr6:28041457 NA 0.34 5.75 0.3 2.02e-8 Cardiac Troponin-T levels; LIHC cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg27170947 chr2:26402098 FAM59B 0.67 8.4 0.41 1.19e-15 Gut microbiome composition (summer); LIHC cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg16405210 chr4:1374714 KIAA1530 -0.44 -6.67 -0.34 1.01e-10 Obesity-related traits; LIHC cis rs35306767 0.855 rs55708963 chr10:925712 C/A cg26597838 chr10:835615 NA 1.46 16.71 0.67 3.08e-46 Eosinophil percentage of granulocytes; LIHC cis rs743757 1.000 rs2282752 chr3:50433967 G/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.51 7.97 0.4 2.47e-14 Diastolic blood pressure; LIHC cis rs17496827 0.780 rs36099214 chr2:223354888 G/A cg25565276 chr2:223520875 FARSB 0.43 6.26 0.32 1.13e-9 Anorexia nervosa; LIHC trans rs11098499 0.697 rs6832410 chr4:120296800 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg12516959 chr21:47718080 NA -0.43 -7.04 -0.36 1.09e-11 Testicular germ cell tumor; LIHC cis rs240764 0.621 rs11752659 chr6:101212241 A/G cg09795085 chr6:101329169 ASCC3 -0.56 -8.09 -0.4 1.09e-14 Neuroticism; LIHC cis rs7772486 0.790 rs6570724 chr6:146151283 T/C cg13319975 chr6:146136371 FBXO30 -0.34 -5.78 -0.3 1.7e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7249142 0.506 rs8101388 chr19:19293938 A/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.4 -6.66 -0.34 1.07e-10 IgG glycosylation; LIHC cis rs7945718 0.533 rs10765987 chr11:12705743 C/T cg25843174 chr11:12811716 TEAD1 0.33 7.51 0.38 5.22e-13 Educational attainment (years of education); LIHC cis rs6977660 0.714 rs4719587 chr7:19828174 C/G cg07541023 chr7:19748670 TWISTNB 0.41 6.04 0.31 3.97e-9 Thyroid stimulating hormone; LIHC cis rs7552404 1.000 rs12127402 chr1:76205643 C/A cg10523679 chr1:76189770 ACADM 0.63 8.72 0.43 1.23e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs941408 0.890 rs1640269 chr19:2793194 A/C cg06609049 chr19:2785107 THOP1 0.56 9.84 0.47 2.88e-20 Total cholesterol levels; LIHC cis rs78456975 1.000 rs13429866 chr2:1555211 C/A cg01028140 chr2:1542097 TPO -0.56 -6.64 -0.34 1.27e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.29 -0.45 1.83e-18 Bipolar disorder; LIHC cis rs4665809 1.000 rs4665305 chr2:26313524 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.85 -0.43 4.72e-17 Gut microbiome composition (summer); LIHC cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg26818010 chr10:134567672 INPP5A -0.79 -9.6 -0.46 1.81e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1395 1.000 rs6717980 chr2:27452784 T/C cg23587288 chr2:27483067 SLC30A3 -0.29 -5.74 -0.3 2.08e-8 Blood metabolite levels; LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg21248554 chr2:27665150 KRTCAP3 -0.43 -5.79 -0.3 1.6e-8 Total body bone mineral density; LIHC cis rs11888559 0.655 rs7596118 chr2:204014655 G/A cg24605529 chr2:203879461 NBEAL1 0.77 5.85 0.3 1.16e-8 Height; LIHC cis rs736408 0.648 rs3774355 chr3:52817778 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.48 7.61 0.38 2.76e-13 Bipolar disorder; LIHC cis rs2257205 0.667 rs8077548 chr17:56690848 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs8084351 0.577 rs7235008 chr18:50632813 C/T cg24270629 chr18:50823537 DCC -0.41 -6.21 -0.32 1.53e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs875971 0.660 rs10229345 chr7:65982168 G/C cg26939375 chr7:64535504 NA 0.43 6.6 0.34 1.56e-10 Aortic root size; LIHC cis rs9303280 0.934 rs8065777 chr17:38072402 C/T cg11212589 chr17:38028394 ZPBP2 -0.34 -6.67 -0.34 1.02e-10 Self-reported allergy; LIHC cis rs12744310 1.000 rs12039767 chr1:41760860 C/T cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.72e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9381040 0.655 rs7775972 chr6:41038116 A/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.37 -6.07 -0.31 3.37e-9 Alzheimer's disease (late onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03315687 chr19:40932206 SERTAD1 0.46 6.72 0.34 7.8e-11 Pancreatic cancer; LIHC cis rs4700695 0.614 rs153388 chr5:65422308 G/T cg21114390 chr5:65439923 SFRS12 -0.55 -6.14 -0.32 2.27e-9 Facial morphology (factor 19); LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.67 0.62 4.01e-38 Prudent dietary pattern; LIHC cis rs208520 0.661 rs7766144 chr6:66827795 C/T cg07460842 chr6:66804631 NA -0.76 -8.35 -0.41 1.75e-15 Exhaled nitric oxide output; LIHC cis rs4819052 0.851 rs9974891 chr21:46680767 T/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.85 0.39 5.29e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7589728 0.563 rs78685993 chr2:88447026 T/C cg04511125 chr2:88470314 THNSL2 0.97 9.88 0.47 1.97e-20 Plasma clusterin levels; LIHC cis rs10792665 0.541 rs7106519 chr11:82628030 A/G cg24227371 chr11:82718527 RAB30 0.28 6.56 0.33 2.05e-10 Obesity-related traits; LIHC cis rs138880 0.542 rs9616371 chr22:50306338 G/A cg09182678 chr22:50328711 NA -0.7 -7.8 -0.39 7.52e-14 Schizophrenia; LIHC cis rs8141529 0.778 rs9625566 chr22:29162506 G/A cg02153584 chr22:29168773 CCDC117 0.57 8.94 0.44 2.43e-17 Lymphocyte counts; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg04013166 chr16:89971882 TCF25 -0.64 -9.25 -0.45 2.51e-18 Skin colour saturation; LIHC cis rs9733 0.628 rs7540874 chr1:150702663 A/C cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs1023500 1.000 rs10154646 chr22:42331409 G/C cg04733989 chr22:42467013 NAGA -0.52 -6.1 -0.31 2.89e-9 Schizophrenia; LIHC cis rs1008375 1.000 rs4642241 chr4:17617111 T/C cg04450456 chr4:17643702 FAM184B 0.35 5.85 0.3 1.16e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1577917 1.000 rs12207305 chr6:86723502 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.11 -0.48 3.3e-21 Response to antipsychotic treatment; LIHC cis rs754466 0.580 rs10824571 chr10:79531931 G/A cg17075019 chr10:79541650 NA -0.79 -12.07 -0.55 3.59e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6120849 0.754 rs13433216 chr20:33616301 T/C cg24642439 chr20:33292090 TP53INP2 0.65 7.0 0.35 1.36e-11 Protein C levels; LIHC cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg20295408 chr7:1910781 MAD1L1 0.44 6.49 0.33 3.06e-10 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs3938660 chr6:8443335 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg18305652 chr10:134549665 INPP5A -0.43 -6.22 -0.32 1.45e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.11 -0.68 7.46e-48 Gut microbiome composition (summer); LIHC cis rs9868809 0.881 rs2276852 chr3:48666923 A/G cg07636037 chr3:49044803 WDR6 -0.53 -6.45 -0.33 3.84e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg21782813 chr7:2030301 MAD1L1 0.37 6.32 0.32 8.28e-10 Bipolar disorder and schizophrenia; LIHC cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg02187348 chr16:89574699 SPG7 0.7 11.11 0.51 1.1e-24 Multiple myeloma (IgH translocation); LIHC cis rs2204008 0.728 rs12369538 chr12:38443942 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.45 0.42 8.19e-16 Bladder cancer; LIHC cis rs9457247 1.000 rs421214 chr6:167396629 A/G cg23791538 chr6:167370224 RNASET2 -0.67 -11.56 -0.53 2.49e-26 Crohn's disease; LIHC cis rs8081395 0.775 rs2645482 chr17:57943115 T/G cg13753209 chr17:57696993 CLTC 0.39 5.81 0.3 1.44e-8 White blood cell count; LIHC cis rs35110281 0.622 rs9977258 chr21:44976485 G/T cg21573476 chr21:45109991 RRP1B -0.55 -10.31 -0.49 6.75e-22 Mean corpuscular volume; LIHC cis rs2806561 0.704 rs2806570 chr1:23527005 C/T cg12483005 chr1:23474871 LUZP1 -0.47 -7.28 -0.37 2.3e-12 Height; LIHC cis rs12477438 0.501 rs11692336 chr2:99740606 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs11764590 0.694 rs4721321 chr7:2068470 A/G cg23043544 chr7:2124092 MAD1L1 -0.43 -6.95 -0.35 1.86e-11 Neuroticism; LIHC cis rs7582180 0.676 rs6542940 chr2:100982144 A/T cg14675211 chr2:100938903 LONRF2 0.53 8.0 0.4 2e-14 Intelligence (multi-trait analysis); LIHC cis rs75908454 1.000 rs74792903 chr6:169836217 C/T cg19338460 chr6:170058176 WDR27 -0.86 -7.77 -0.39 9.33e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs7618501 0.633 rs2624843 chr3:49997963 G/A cg21467203 chr3:49911342 NA -0.45 -8.11 -0.4 9.27e-15 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs1892700 0.764 rs34927129 chr21:34873502 G/A cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.97e-8 Educational attainment; LIHC cis rs56775891 1.000 rs6650631 chr18:77566535 G/C cg13263691 chr18:77568018 NA 0.25 6.76 0.34 6.13e-11 Schizophrenia; LIHC cis rs7772486 0.875 rs1412081 chr6:146409733 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.78 -0.3 1.69e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7552404 1.000 rs942270 chr1:76177332 G/A cg03433033 chr1:76189801 ACADM 0.67 9.27 0.45 2.19e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11190604 0.767 rs3829162 chr10:102172752 T/G cg07080220 chr10:102295463 HIF1AN 0.44 6.01 0.31 4.78e-9 Palmitoleic acid (16:1n-7) levels; LIHC trans rs7613875 0.600 rs2624832 chr3:50030858 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.43 6.57 0.33 1.89e-10 Body mass index; LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg24209194 chr3:40518798 ZNF619 0.56 8.17 0.4 5.9e-15 Renal cell carcinoma; LIHC cis rs6545883 0.929 rs6545877 chr2:61741947 T/C cg14146966 chr2:61757674 XPO1 0.47 8.37 0.41 1.53e-15 Tuberculosis; LIHC cis rs2197308 0.740 rs1842595 chr12:37906223 G/A cg26384229 chr12:38710491 ALG10B -0.47 -6.64 -0.34 1.23e-10 Morning vs. evening chronotype; LIHC cis rs4808199 1.000 rs7258508 chr19:19475469 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.55 0.38 3.97e-13 Nonalcoholic fatty liver disease; LIHC cis rs10791097 0.765 rs10894269 chr11:130722789 C/T cg09137382 chr11:130731461 NA 0.41 6.24 0.32 1.28e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12928939 0.954 rs8057568 chr16:71811995 G/A cg03805757 chr16:71968109 PKD1L3 -0.74 -8.81 -0.43 6.2e-17 Post bronchodilator FEV1; LIHC cis rs9303280 0.901 rs869402 chr17:38068043 C/T cg11212589 chr17:38028394 ZPBP2 0.32 6.6 0.34 1.55e-10 Self-reported allergy; LIHC cis rs72627509 0.951 rs6554401 chr4:57825336 C/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.56 -8.38 -0.41 1.38e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7100689 0.646 rs12253992 chr10:82158710 G/A cg01528321 chr10:82214614 TSPAN14 0.65 9.88 0.47 1.98e-20 Post bronchodilator FEV1; LIHC cis rs4820539 0.966 rs2267005 chr22:23461723 A/G cg14186256 chr22:23484241 RTDR1 0.96 19.89 0.73 4.86e-59 Bone mineral density; LIHC cis rs2380220 0.541 rs9285413 chr6:96023439 G/A cg04719120 chr6:96025338 MANEA 0.7 8.16 0.4 6.49e-15 Behavioural disinhibition (generation interaction); LIHC cis rs155076 0.666 rs9509640 chr13:21872880 T/C cg14456004 chr13:21872349 NA 1.39 15.44 0.64 3.57e-41 White matter hyperintensity burden; LIHC cis rs61990749 0.597 rs10136053 chr14:78155205 G/A cg21497246 chr14:78225524 SNW1;C14orf178 0.5 7.74 0.39 1.1e-13 Fibroblast growth factor basic levels; LIHC cis rs17445774 1.000 rs1509833 chr2:200865225 G/A cg23649088 chr2:200775458 C2orf69 0.66 7.65 0.38 2.08e-13 LDL cholesterol to HDL cholesterol ratio; LIHC cis rs471756 0.523 rs574399 chr9:219875 T/A cg14500300 chr9:211689 NA 0.25 5.81 0.3 1.45e-8 Mean platelet volume; LIHC cis rs7940866 0.834 rs10791105 chr11:130839161 A/G cg12179176 chr11:130786555 SNX19 0.64 9.25 0.45 2.4e-18 Schizophrenia; LIHC cis rs7552167 0.789 rs6424162 chr1:24512576 T/C cg01960748 chr1:24522592 NA -0.79 -9.62 -0.46 1.55e-19 Psoriasis vulgaris; LIHC cis rs7586673 0.930 rs7591506 chr2:161960925 T/G cg13854012 chr2:162103682 NA -0.32 -5.71 -0.3 2.45e-8 Intelligence (multi-trait analysis); LIHC cis rs7249142 0.563 rs11669860 chr19:19277296 G/A cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.4 -6.53 -0.33 2.43e-10 IgG glycosylation; LIHC cis rs968567 0.539 rs174549 chr11:61571382 A/G cg07689907 chr11:61582574 FADS1 -0.39 -5.72 -0.3 2.3e-8 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg04944784 chr2:26401820 FAM59B 0.71 9.11 0.44 7.26e-18 Gut microbiome composition (summer); LIHC trans rs7668874 0.731 rs1835504 chr4:116790996 T/G cg08917878 chr5:172668965 NA -0.3 -6.04 -0.31 4e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs7542091 0.704 rs1883331 chr1:210043483 A/G cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC trans rs1814175 0.817 rs6486046 chr11:49997017 T/C cg15704280 chr7:45808275 SEPT13 -1.0 -23.31 -0.78 1.3e-72 Height; LIHC cis rs2361718 0.933 rs8066452 chr17:78104080 A/G cg09238746 chr17:78121135 EIF4A3 -0.48 -7.2 -0.36 3.8e-12 Yeast infection; LIHC trans rs4843747 0.671 rs72818540 chr16:88078988 C/T cg26811252 chr16:29126840 RRN3P2 0.44 6.87 0.35 3.13e-11 Menopause (age at onset); LIHC trans rs561341 1.000 rs554078 chr17:30330109 A/C cg20587970 chr11:113659929 NA -1.49 -12.54 -0.56 6.15e-30 Hip circumference adjusted for BMI; LIHC cis rs899997 1.000 rs11072793 chr15:79006442 C/T cg04896959 chr15:78267971 NA 0.4 7.88 0.39 4.39e-14 Coronary artery disease or large artery stroke; LIHC cis rs911119 1.000 rs13038305 chr20:23610262 C/T cg16589663 chr20:23618590 CST3 0.74 7.75 0.39 1.09e-13 Chronic kidney disease; LIHC cis rs5753618 0.539 rs2228619 chr22:31663842 C/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs9303401 0.659 rs62081316 chr17:56781499 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 11.98 0.54 7.57e-28 Cognitive test performance; LIHC cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg13393036 chr8:95962371 TP53INP1 0.39 8.03 0.4 1.54e-14 Type 2 diabetes; LIHC cis rs9916302 0.904 rs2338755 chr17:37419317 C/T cg00129232 chr17:37814104 STARD3 0.38 6.05 0.31 3.76e-9 Glomerular filtration rate (creatinine); LIHC cis rs992157 0.735 rs12990082 chr2:219102332 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.61 0.59 5.31e-34 Colorectal cancer; LIHC cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg26939375 chr7:64535504 NA 0.47 7.09 0.36 7.94e-12 Calcium levels; LIHC cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg21171335 chr12:122356390 WDR66 0.57 8.07 0.4 1.2e-14 Mean corpuscular volume; LIHC cis rs1799949 0.965 rs8071278 chr17:41193910 A/T cg25072359 chr17:41440525 NA 0.41 6.42 0.33 4.43e-10 Menopause (age at onset); LIHC cis rs8077889 0.672 rs2074143 chr17:41856622 A/G cg26893861 chr17:41843967 DUSP3 1.04 17.95 0.7 3.13e-51 Triglycerides; LIHC cis rs7248779 0.512 rs3848635 chr19:2410332 T/C cg22729335 chr19:2427816 TIMM13 1.05 20.08 0.74 8.39e-60 Cortisol levels (saliva); LIHC cis rs748404 0.660 rs542898 chr15:43719392 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.1e-13 Lung cancer; LIHC cis rs1878931 0.535 rs55732163 chr16:3411518 A/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.68 -8.93 -0.43 2.65e-17 Body mass index (adult); LIHC cis rs7131987 0.868 rs11050151 chr12:29403008 T/A cg21486233 chr12:29375141 FAR2 0.32 6.44 0.33 4.07e-10 QT interval; LIHC cis rs7818688 0.697 rs76815619 chr8:95981330 G/A cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs1814175 0.616 rs10839341 chr11:49742615 G/A cg03929089 chr4:120376271 NA -0.85 -16.54 -0.67 1.44e-45 Height; LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg08469215 chr1:156261351 TMEM79 0.4 6.5 0.33 2.84e-10 Tonsillectomy; LIHC cis rs7927771 0.832 rs11607981 chr11:47401060 T/G cg20135002 chr11:47629003 NA -0.51 -8.59 -0.42 3.11e-16 Subjective well-being; LIHC trans rs526821 0.595 rs485555 chr11:55323570 A/G cg03929089 chr4:120376271 NA 0.45 6.82 0.35 4.18e-11 Pediatric bone mineral density (spine); LIHC cis rs7613875 0.600 rs7061 chr3:50114515 C/T cg24110177 chr3:50126178 RBM5 0.58 9.57 0.46 2.17e-19 Body mass index; LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg20570016 chr1:156261298 TMEM79 0.37 5.94 0.31 7.11e-9 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs8049603 0.524 rs36044995 chr16:23086965 T/G cg16484020 chr16:23217411 SCNN1G -0.24 -5.99 -0.31 5.24e-9 Multiple sclerosis; LIHC cis rs10791323 0.628 rs10750543 chr11:133718467 G/A cg06766960 chr11:133703094 NA -0.65 -11.11 -0.51 1.09e-24 Childhood ear infection; LIHC cis rs1707322 0.893 rs9919275 chr1:46441360 A/C cg03146154 chr1:46216737 IPP 0.48 7.86 0.39 5.02e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11229555 0.645 rs12285111 chr11:58208385 T/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs71007656 1 rs71007656 chr10:37970845 CGGCTG/C cg17830980 chr10:43048298 ZNF37B -0.43 -8.17 -0.4 5.87e-15 Extrinsic epigenetic age acceleration; LIHC cis rs7772486 0.875 rs2777476 chr6:146345024 A/G cg23711669 chr6:146136114 FBXO30 0.67 11.83 0.54 2.65e-27 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.616 rs1722001 chr11:49894427 A/G cg03929089 chr4:120376271 NA -0.83 -15.97 -0.65 2.6900000000000002e-43 Height; LIHC cis rs2073300 1.000 rs6132623 chr20:23442324 T/A cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9517320 0.534 rs61969451 chr13:99167654 A/T cg20487152 chr13:99095054 FARP1 -0.37 -6.14 -0.32 2.29e-9 Longevity; LIHC cis rs2153535 0.580 rs962590 chr6:8450899 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC cis rs8141529 0.764 rs5762824 chr22:29222930 C/T cg15103426 chr22:29168792 CCDC117 0.67 11.37 0.52 1.29e-25 Lymphocyte counts; LIHC cis rs2073499 0.872 rs7642692 chr3:50222693 T/C cg03645007 chr3:50255295 SLC38A3 0.44 6.2 0.32 1.59e-9 Schizophrenia; LIHC cis rs959260 1.000 rs4789183 chr17:73380221 G/A cg20590849 chr17:73267439 MIF4GD -0.54 -5.8 -0.3 1.51e-8 Systemic lupus erythematosus; LIHC cis rs6952808 0.707 rs13244345 chr7:1973004 A/G cg02951883 chr7:2050386 MAD1L1 -0.59 -9.14 -0.44 5.7e-18 Bipolar disorder and schizophrenia; LIHC cis rs7238033 0.624 rs10460036 chr18:43311566 A/G cg20610511 chr18:43302872 SLC14A1 0.38 6.34 0.32 7.42e-10 Bladder cancer; LIHC cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg00750074 chr16:89608354 SPG7 -0.39 -5.88 -0.3 9.79e-9 Multiple myeloma (IgH translocation); LIHC cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs10791097 0.677 rs11222359 chr11:130730648 A/G cg09137382 chr11:130731461 NA 0.42 6.35 0.32 6.9e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs8010715 0.771 rs2277481 chr14:24587545 A/G cg23112188 chr14:24563095 PCK2 -0.3 -6.33 -0.32 7.88e-10 IgG glycosylation; LIHC trans rs1814175 0.702 rs4881644 chr11:49786367 C/T cg03929089 chr4:120376271 NA -0.89 -18.21 -0.7 2.89e-52 Height; LIHC cis rs9486719 0.895 rs3798294 chr6:97049587 G/A cg18709589 chr6:96969512 KIAA0776 -0.47 -5.76 -0.3 1.83e-8 Migraine;Coronary artery disease; LIHC cis rs1982963 0.950 rs1566132 chr14:52511836 C/T cg10843707 chr14:52510701 NID2 -0.44 -8.23 -0.41 4.08e-15 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.815 rs16921955 chr8:58164553 C/T cg02290350 chr8:58132656 NA 0.4 8.5 0.42 6.01e-16 Developmental language disorder (linguistic errors); LIHC cis rs459571 0.839 rs2519831 chr9:136886257 T/A cg13789015 chr9:136890014 NCRNA00094 0.45 8.39 0.41 1.29e-15 Platelet distribution width; LIHC cis rs10883723 0.810 rs7072351 chr10:104265047 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.76 0.57 9.39e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs12477438 0.798 rs6705821 chr2:99602832 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.6 -0.5 6.66e-23 Chronic sinus infection; LIHC trans rs2727020 0.729 rs685789 chr11:49241228 G/A cg15704280 chr7:45808275 SEPT13 0.88 15.77 0.65 1.67e-42 Coronary artery disease; LIHC cis rs2797160 0.967 rs2226158 chr6:125995467 C/T cg05901451 chr6:126070800 HEY2 -0.52 -9.61 -0.46 1.59e-19 Endometrial cancer; LIHC trans rs2727020 0.595 rs7924311 chr11:49507573 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -22.14 -0.77 5.15e-68 Coronary artery disease; LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.97 -0.31 6.04e-9 Menopause (age at onset); LIHC cis rs3768617 0.510 rs3768618 chr1:183092491 C/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs12477438 0.520 rs4588238 chr2:99749350 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.37 0.77 6.21e-69 Chronic sinus infection; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12868349 chr11:71639594 RNF121;LOC100133315 0.42 6.22 0.32 1.47e-9 Cognitive function; LIHC trans rs2243480 1.000 rs316304 chr7:65616894 T/C cg10756647 chr7:56101905 PSPH 1.1 13.4 0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs3099143 1.000 rs4583202 chr15:77161676 G/A cg21673338 chr15:77095150 SCAPER 0.49 7.59 0.38 3.01e-13 Recalcitrant atopic dermatitis; LIHC cis rs4906332 1.000 rs2065015 chr14:103904061 G/T cg19000871 chr14:103996768 TRMT61A 0.43 7.35 0.37 1.45e-12 Coronary artery disease; LIHC cis rs477692 0.905 rs4751106 chr10:131424653 G/T cg05714579 chr10:131428358 MGMT -0.5 -8.54 -0.42 4.46e-16 Response to temozolomide; LIHC cis rs918629 0.530 rs11741563 chr5:95240996 C/T cg10483112 chr5:95245456 ELL2 -0.38 -6.91 -0.35 2.34e-11 IgG glycosylation; LIHC cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg06481639 chr22:41940642 POLR3H -0.71 -7.13 -0.36 5.83e-12 Vitiligo; LIHC cis rs2073300 0.609 rs6137920 chr20:23363436 C/T cg12062639 chr20:23401060 NAPB 1.08 13.95 0.6 2.44e-35 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs919433 0.680 rs2564383 chr2:198310862 A/G cg10820045 chr2:198174542 NA 0.54 8.82 0.43 5.8e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17106184 0.786 rs113611542 chr1:51129203 T/C cg07174182 chr1:51127561 FAF1 -0.76 -8.12 -0.4 8.47e-15 Type 2 diabetes; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg14307443 chr4:172734507 GALNTL6 0.39 7.0 0.35 1.37e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2073300 0.609 rs6132609 chr20:23400412 A/C cg12062639 chr20:23401060 NAPB 1.05 14.07 0.61 8.82e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg12463550 chr7:65579703 CRCP 0.68 7.05 0.36 9.9e-12 Diabetic kidney disease; LIHC cis rs11229555 0.609 rs12273517 chr11:58201094 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs11792861 0.530 rs1772047 chr9:111679012 A/G cg05043794 chr9:111880884 C9orf5 0.29 7.13 0.36 5.83e-12 Menarche (age at onset); LIHC cis rs9901225 1 rs9901225 chr17:40755811 C/T cg07694864 chr17:40700509 NA -0.41 -6.9 -0.35 2.49e-11 Colorectal or endometrial cancer; LIHC cis rs7520050 0.966 rs4660319 chr1:46341623 C/T cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs4450131 0.522 rs11245327 chr10:126358174 T/C cg20435097 chr10:126320824 FAM53B 0.67 12.05 0.55 4.05e-28 White blood cell count (basophil); LIHC cis rs4808199 0.947 rs10401193 chr19:19591066 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.41 5.9 0.3 8.98e-9 Nonalcoholic fatty liver disease; LIHC cis rs11122272 0.701 rs971533 chr1:231522097 T/C cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs4253772 0.637 rs9627350 chr22:46663017 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.76 6.97 0.35 1.6e-11 LDL cholesterol;Cholesterol, total; LIHC cis rs9583531 0.600 rs754599 chr13:111354788 C/A cg15841412 chr13:111365552 ING1 0.46 5.84 0.3 1.2e-8 Coronary artery disease; LIHC cis rs4474465 1.000 rs10899514 chr11:78172695 A/G cg02023728 chr11:77925099 USP35 0.35 6.19 0.32 1.69e-9 Alzheimer's disease (survival time); LIHC cis rs6988636 1.000 rs11988157 chr8:124194740 A/G cg15893493 chr8:124194847 FAM83A -0.77 -8.05 -0.4 1.36e-14 Urinary uromodulin levels; LIHC cis rs3862030 0.510 rs11591780 chr10:104225316 C/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -6.99 -0.35 1.46e-11 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs6570726 0.837 rs419991 chr6:145864212 C/T cg23711669 chr6:146136114 FBXO30 0.56 10.02 0.48 7.09e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs12586317 0.547 rs28395170 chr14:35506988 C/T cg16230307 chr14:35515116 FAM177A1 0.82 13.77 0.6 1.2e-34 Psoriasis; LIHC cis rs1707322 0.717 rs1135850 chr1:46093692 G/A cg03146154 chr1:46216737 IPP 0.55 9.08 0.44 9e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs244293 0.965 rs244366 chr17:53187300 G/C cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.47 -0.37 6.93e-13 Menarche (age at onset); LIHC cis rs2153535 0.580 rs9328479 chr6:8519646 A/G cg21535247 chr6:8435926 SLC35B3 0.63 8.29 0.41 2.64e-15 Motion sickness; LIHC cis rs2153535 0.580 rs1577471 chr6:8485905 T/A cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs4742903 0.967 rs2274725 chr9:106864570 C/T cg14250997 chr9:106856677 SMC2 0.42 7.45 0.37 7.54e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2637030 0.559 rs2607497 chr5:52995482 A/G cg06476337 chr5:52856530 NDUFS4 0.42 6.73 0.34 6.99e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs6690583 0.623 rs12033900 chr1:85478559 T/C cg22153463 chr1:85462885 MCOLN2 0.49 5.87 0.3 1.03e-8 Serum sulfate level; LIHC cis rs763121 0.853 rs2413546 chr22:39107001 G/A cg06022373 chr22:39101656 GTPBP1 0.64 10.82 0.5 1.19e-23 Menopause (age at onset); LIHC cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs986417 0.892 rs78026410 chr14:60801142 G/A cg27398547 chr14:60952738 C14orf39 -0.73 -7.72 -0.39 1.3e-13 Gut microbiota (bacterial taxa); LIHC cis rs5769765 0.908 rs9616216 chr22:50318927 T/C cg09182678 chr22:50328711 NA -0.39 -5.82 -0.3 1.36e-8 Schizophrenia; LIHC cis rs4631830 0.720 rs113082846 chr10:51502802 G/C cg20129853 chr10:51489980 NA -0.39 -8.57 -0.42 3.49e-16 Prostate-specific antigen levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01506492 chr2:219232590 C2orf62 -0.44 -6.07 -0.31 3.41e-9 Longevity; LIHC cis rs11190604 0.767 rs35508946 chr10:102191156 A/G cg07080220 chr10:102295463 HIF1AN 0.47 6.93 0.35 2.08e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9381040 0.610 rs2268196 chr6:41021950 C/G cg25110423 chr6:41068646 NFYA;LOC221442 0.37 5.9 0.3 8.77e-9 Alzheimer's disease (late onset); LIHC cis rs4689592 0.619 rs3796908 chr4:7061378 G/A cg19539972 chr4:7069911 GRPEL1 0.67 9.82 0.47 3.18e-20 Monocyte percentage of white cells; LIHC trans rs1814175 0.588 rs10466497 chr11:49864381 A/T cg15704280 chr7:45808275 SEPT13 -0.95 -19.97 -0.73 2.38e-59 Height; LIHC cis rs9828933 0.752 rs832192 chr3:63853423 T/C cg16258503 chr3:63850278 ATXN7;THOC7 0.81 10.2 0.48 1.72e-21 Type 2 diabetes; LIHC cis rs9517313 0.770 rs9517301 chr13:99095088 A/G cg07423050 chr13:99094983 FARP1 -0.62 -11.95 -0.54 9.94e-28 Neuroticism; LIHC cis rs1215050 0.791 rs165252 chr4:98758728 A/C cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg11764359 chr7:65958608 NA 0.59 6.11 0.31 2.74e-9 Diabetic kidney disease; LIHC cis rs911119 0.913 rs13038990 chr20:23589053 C/T cg16589663 chr20:23618590 CST3 0.71 7.5 0.38 5.61e-13 Chronic kidney disease; LIHC cis rs2204008 0.774 rs7305085 chr12:38263511 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs11077998 0.933 rs6502121 chr17:80531314 A/G cg10255544 chr17:80519551 FOXK2 0.48 8.53 0.42 4.71e-16 Reticulocyte fraction of red cells; LIHC cis rs55665837 0.701 rs12286408 chr11:14579376 G/A cg00085434 chr11:14927489 NA 0.43 6.07 0.31 3.32e-9 Vitamin D levels; LIHC cis rs67478160 0.634 rs941473 chr14:104201869 C/G cg01849466 chr14:104193079 ZFYVE21 -0.54 -9.52 -0.46 3.25e-19 Schizophrenia; LIHC cis rs763121 0.853 rs138716 chr22:39146527 C/T cg14440974 chr22:39074834 NA -0.39 -6.3 -0.32 9.41e-10 Menopause (age at onset); LIHC cis rs151997 0.925 rs26089 chr5:50172251 A/G cg06027927 chr5:50259733 NA -0.55 -7.32 -0.37 1.76e-12 Callous-unemotional behaviour; LIHC cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg16606324 chr3:10149918 C3orf24 0.49 5.75 0.3 1.94e-8 Alzheimer's disease; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.28 0.52 2.61e-25 Prudent dietary pattern; LIHC cis rs765787 0.530 rs4514617 chr15:45535439 A/G cg24006582 chr15:45444508 DUOX1 -0.51 -7.26 -0.37 2.63e-12 Uric acid levels; LIHC cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg20607798 chr8:58055168 NA 0.48 5.98 0.31 5.72e-9 Developmental language disorder (linguistic errors); LIHC cis rs10484885 0.588 rs9344947 chr6:90304789 A/G cg13799429 chr6:90582589 CASP8AP2 0.58 6.22 0.32 1.49e-9 QRS interval (sulfonylurea treatment interaction); LIHC cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg23172400 chr8:95962367 TP53INP1 -0.36 -8.02 -0.4 1.7e-14 Type 2 diabetes; LIHC cis rs7772486 0.790 rs3924498 chr6:146233338 A/T cg05347473 chr6:146136440 FBXO30 -0.39 -6.16 -0.32 2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6733011 0.508 rs4851173 chr2:99520608 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.57 -0.33 1.83e-10 Bipolar disorder; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg09364756 chr6:160148626 WTAP 0.34 6.22 0.32 1.48e-9 Calcium levels; LIHC cis rs11628318 0.715 rs1815262 chr14:103056926 C/T cg12046867 chr14:103022105 NA -0.5 -6.94 -0.35 1.97e-11 Platelet count; LIHC cis rs2576037 0.562 rs13381557 chr18:44513371 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.71 11.43 0.53 7.93e-26 Personality dimensions; LIHC cis rs6690583 0.524 rs12029690 chr1:85452867 C/G cg22153463 chr1:85462885 MCOLN2 0.52 6.22 0.32 1.42e-9 Serum sulfate level; LIHC cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.85 0.35 3.35e-11 Gut microbiome composition (summer); LIHC cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg12463550 chr7:65579703 CRCP -0.65 -6.98 -0.35 1.57e-11 Diabetic kidney disease; LIHC cis rs785830 0.523 rs529045 chr9:217397 C/T cg14500300 chr9:211689 NA 0.26 5.85 0.3 1.15e-8 Platelet distribution width; LIHC cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.686 rs4896828 chr6:145953339 A/C cg23711669 chr6:146136114 FBXO30 0.69 12.59 0.56 4.11e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.51 0.33 2.68e-10 Bipolar disorder; LIHC cis rs921968 0.541 rs58650092 chr2:219304851 C/A cg02176678 chr2:219576539 TTLL4 -0.58 -8.09 -0.4 1.04e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 0.882 rs56224841 chr3:10044014 A/C cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg07092213 chr7:1199455 ZFAND2A -0.44 -6.42 -0.33 4.45e-10 Longevity;Endometriosis; LIHC cis rs703842 1.000 rs4646536 chr12:58157988 A/G cg18357645 chr12:58087776 OS9 -0.43 -6.76 -0.34 6.05e-11 Multiple sclerosis; LIHC cis rs13108904 0.518 rs4974603 chr4:1343168 C/T cg13395646 chr4:1353034 KIAA1530 -0.84 -12.79 -0.57 7.28e-31 Obesity-related traits; LIHC cis rs4665809 1.000 rs2053367 chr2:26293413 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.88 -0.43 3.95e-17 Gut microbiome composition (summer); LIHC cis rs875971 1.000 rs10215948 chr7:65747786 G/A cg18252515 chr7:66147081 NA 0.43 6.07 0.31 3.42e-9 Aortic root size; LIHC cis rs7552404 0.696 rs12140121 chr1:76455001 A/G cg10523679 chr1:76189770 ACADM 0.61 7.25 0.37 2.75e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8062405 0.964 rs11860513 chr16:28825420 C/T cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.26e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg02290350 chr8:58132656 NA 0.49 10.45 0.49 2.26e-22 Developmental language disorder (linguistic errors); LIHC cis rs1494950 1.000 rs7667955 chr4:15084922 A/G cg12377275 chr4:15005593 CPEB2 -0.86 -7.69 -0.38 1.5700000000000001e-13 Political ideology; LIHC cis rs67460515 0.892 rs1382429 chr3:161015153 T/C cg03342759 chr3:160939853 NMD3 -0.64 -9.6 -0.46 1.82e-19 Parkinson's disease; LIHC cis rs9905704 0.647 rs2108435 chr17:57102133 T/C cg12560992 chr17:57184187 TRIM37 -0.66 -9.78 -0.47 4.28e-20 Testicular germ cell tumor; LIHC cis rs7100689 0.646 rs1934692 chr10:82125734 C/A cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC trans rs3780486 0.846 rs3780487 chr9:33139237 T/C cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC trans rs10506458 0.915 rs12424908 chr12:63402364 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.73 -10.37 -0.49 4.23e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg20295408 chr7:1910781 MAD1L1 -0.43 -6.34 -0.32 7.3e-10 Bipolar disorder and schizophrenia; LIHC cis rs9916302 0.861 rs12150493 chr17:37586154 T/C cg03013999 chr17:37608204 MED1 0.35 5.8 0.3 1.49e-8 Glomerular filtration rate (creatinine); LIHC cis rs7086627 0.515 rs10887905 chr10:82210855 A/T cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC cis rs7552404 0.924 rs67757078 chr1:76169456 G/A cg03433033 chr1:76189801 ACADM 0.69 10.66 0.5 4.13e-23 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.69 -11.43 -0.53 7.84e-26 Prudent dietary pattern; LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg25894440 chr7:65020034 NA -0.41 -6.65 -0.34 1.17e-10 Calcium levels; LIHC cis rs10791097 0.694 rs7107595 chr11:130758556 C/T cg12179176 chr11:130786555 SNX19 0.88 14.63 0.62 5.74e-38 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs3780486 0.846 rs12554995 chr9:33132044 A/G cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs798554 0.959 rs798557 chr7:2758982 G/A cg13628971 chr7:2884303 GNA12 0.5 7.05 0.36 9.69e-12 Height; LIHC cis rs7927592 0.673 rs498782 chr11:68275851 A/G cg20283391 chr11:68216788 NA -0.36 -5.73 -0.3 2.15e-8 Total body bone mineral density; LIHC cis rs1865760 0.532 rs9295687 chr6:26082710 T/C cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.04 -0.48 5.96e-21 Platelet count; LIHC trans rs6952808 0.595 rs2398705 chr7:2164995 G/A cg04565464 chr8:145669602 NFKBIL2 0.37 6.12 0.31 2.51e-9 Bipolar disorder and schizophrenia; LIHC cis rs9513627 1.000 rs9585075 chr13:100128634 G/A cg25919922 chr13:100150906 NA -0.77 -6.89 -0.35 2.74e-11 Obesity-related traits; LIHC cis rs894734 0.535 rs10783613 chr12:54321966 G/T cg25024717 chr12:54324583 NA -0.38 -8.03 -0.4 1.63e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.48 -6.76 -0.34 6.05e-11 Lymphocyte counts; LIHC cis rs4319547 0.656 rs7975747 chr12:122816995 C/T cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.29 -0.37 2.1e-12 Body mass index; LIHC cis rs12586317 0.534 rs2273157 chr14:35438836 A/G cg05294307 chr14:35346193 BAZ1A -0.46 -7.28 -0.37 2.35e-12 Psoriasis; LIHC cis rs9467773 1.000 rs2255070 chr6:26501777 C/G cg09904177 chr6:26538194 HMGN4 0.66 13.79 0.6 1.01e-34 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.4e-11 Diabetic kidney disease; LIHC cis rs11098499 0.738 rs28687057 chr4:120280812 A/G cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs9611565 0.592 rs4822040 chr22:41963553 C/G cg03806693 chr22:41940476 POLR3H -0.83 -9.2 -0.45 3.68e-18 Vitiligo; LIHC cis rs6952809 0.532 rs6952152 chr7:2440912 G/A cg23289794 chr7:2394357 EIF3B -0.68 -6.63 -0.34 1.34e-10 Multiple sclerosis; LIHC cis rs7927771 1.000 rs10838747 chr11:47716324 G/C cg20135002 chr11:47629003 NA -0.55 -9.53 -0.46 3.1e-19 Subjective well-being; LIHC cis rs2273669 0.588 rs114414265 chr6:109306489 C/A cg05315195 chr6:109294784 ARMC2 -0.52 -5.76 -0.3 1.88e-8 Prostate cancer; LIHC cis rs7078219 0.543 rs7092009 chr10:101277239 A/G cg06854084 chr10:101292507 NKX2-3 -0.35 -6.28 -0.32 1.05e-9 Dental caries; LIHC cis rs4975616 0.869 rs370348 chr5:1331219 A/G cg07493874 chr5:1342172 CLPTM1L -0.68 -10.92 -0.51 5.23e-24 Lung cancer; LIHC cis rs1018836 0.847 rs4735226 chr8:91569238 T/A cg16814680 chr8:91681699 NA -0.61 -9.63 -0.46 1.37e-19 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1538970 0.924 rs1007858 chr1:45912005 C/T cg15605315 chr1:45957053 TESK2 -0.44 -5.74 -0.3 2.08e-8 Platelet count; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17424134 chr2:27616206 FTHL3;PPM1G 0.42 6.22 0.32 1.46e-9 Immature fraction of reticulocytes; LIHC cis rs2120019 1.000 rs67544533 chr15:75361539 A/G cg09165964 chr15:75287851 SCAMP5 -0.65 -10.4 -0.49 3.35e-22 Blood trace element (Zn levels); LIHC cis rs7980687 0.628 rs2851443 chr12:123694250 C/T cg05973401 chr12:123451056 ABCB9 0.42 5.87 0.3 1.01e-8 Height;Educational attainment;Head circumference (infant); LIHC cis rs6754311 0.773 rs1435576 chr2:136641882 A/T cg17750252 chr2:136567154 LCT -0.34 -6.06 -0.31 3.5e-9 Mosquito bite size; LIHC cis rs7582720 1.000 rs72926786 chr2:203816494 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1707322 1.000 rs4134387 chr1:46395158 A/T cg03146154 chr1:46216737 IPP 0.47 7.47 0.37 6.87e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs68170813 0.559 rs1121312 chr7:106927820 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs12478296 1.000 rs7420157 chr2:243005204 G/A cg01596870 chr19:55963115 NA -0.67 -9.61 -0.46 1.58e-19 Obesity-related traits; LIHC trans rs1814175 0.817 rs12277258 chr11:49940216 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs6570726 0.967 rs403584 chr6:145807010 G/A cg23711669 chr6:146136114 FBXO30 0.49 8.86 0.43 4.61e-17 Lobe attachment (rater-scored or self-reported); LIHC trans rs7615952 0.515 rs4267608 chr3:125680500 C/T cg07211511 chr3:129823064 LOC729375 -0.54 -6.83 -0.35 3.94e-11 Blood pressure (smoking interaction); LIHC trans rs3903072 0.652 rs501630 chr11:65637273 A/G cg17712092 chr4:129076599 LARP1B -0.63 -9.02 -0.44 1.33e-17 Breast cancer; LIHC cis rs1005277 0.603 rs1998062 chr10:38457652 G/C cg25427524 chr10:38739819 LOC399744 -0.64 -12.09 -0.55 2.88e-28 Extrinsic epigenetic age acceleration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05047319 chr11:86748661 TMEM135 0.48 6.48 0.33 3.11e-10 Lung function (FEV1/FVC); LIHC cis rs16958440 1.000 rs62096463 chr18:44628928 A/G cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC cis rs9858542 0.953 rs9814873 chr3:49454112 A/G cg03060546 chr3:49711283 APEH -0.48 -6.88 -0.35 2.9e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs769267 0.598 rs8108705 chr19:19675367 G/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.42 -5.75 -0.3 2.02e-8 Tonsillectomy; LIHC cis rs7208859 0.623 rs3752020 chr17:29111125 T/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4822044 0.561 rs132781 chr22:42046122 T/G cg06634786 chr22:41940651 POLR3H 0.73 7.36 0.37 1.35e-12 Cannabis dependence symptom count; LIHC cis rs4908760 0.899 rs6577496 chr1:8581227 C/A cg20416874 chr1:8611966 RERE -0.68 -14.37 -0.61 6.05e-37 Vitiligo; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02590972 chr2:217363392 RPL37A 0.46 6.76 0.34 6.04e-11 Cognitive function; LIHC trans rs1728785 1.000 rs1728801 chr16:68571457 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.82e-9 Ulcerative colitis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10513480 chr14:21852135 SUPT16H -0.58 -6.53 -0.33 2.44e-10 Systolic blood pressure; LIHC cis rs2841277 0.646 rs3742935 chr14:105405599 G/C cg15352829 chr14:105391018 PLD4 -0.43 -9.22 -0.45 3.04e-18 Rheumatoid arthritis; LIHC cis rs2408955 0.504 rs11168441 chr12:48576054 G/A cg21466736 chr12:48725269 NA -0.63 -9.13 -0.44 6.08e-18 Glycated hemoglobin levels; LIHC cis rs254781 0.505 rs664366 chr5:88055761 A/G cg22951263 chr5:87985283 NA -0.39 -6.34 -0.32 7.06e-10 Intelligence (multi-trait analysis); LIHC cis rs895636 0.898 rs10205310 chr2:45188646 A/G cg16198908 chr2:45192207 NA 0.4 6.09 0.31 3.1e-9 Metabolite levels;Fasting plasma glucose; LIHC cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg02969873 chr4:1330999 MAEA -0.42 -6.31 -0.32 8.77e-10 Longevity; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg06873352 chr17:61820015 STRADA 0.73 12.73 0.57 1.16e-30 Prudent dietary pattern; LIHC cis rs7520050 0.931 rs7526678 chr1:46374159 A/G cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.97e-9 Red blood cell count;Reticulocyte count; LIHC cis rs79839061 0.520 rs11730111 chr4:942833 C/T cg07828340 chr4:882639 GAK 0.76 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs8072100 0.935 rs12150231 chr17:45717091 G/A cg15066416 chr17:45501628 LOC100272146;C17orf57 0.36 5.78 0.3 1.7e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7589728 0.844 rs2363010 chr2:88496399 G/C cg07952391 chr2:88470173 THNSL2 0.76 6.94 0.35 1.95e-11 Plasma clusterin levels; LIHC cis rs7617773 0.780 rs4392440 chr3:48343920 C/T cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs2842992 0.789 rs4235925 chr6:160202860 C/T cg11366901 chr6:160182831 ACAT2 0.93 15.9 0.65 5.01e-43 Age-related macular degeneration (geographic atrophy); LIHC cis rs11031096 0.676 rs7120125 chr11:3941264 C/T cg18678763 chr11:4115507 RRM1 0.45 6.57 0.33 1.91e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20910303 chr4:147443095 SLC10A7 0.38 6.21 0.32 1.51e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2228479 0.717 rs1800358 chr16:89809319 T/C cg19635926 chr16:89946313 TCF25 0.46 6.0 0.31 5.11e-9 Skin colour saturation; LIHC cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg25894440 chr7:65020034 NA 0.56 6.48 0.33 3.21e-10 Diabetic kidney disease; LIHC cis rs9486719 0.895 rs11152960 chr6:96900398 A/G cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.32e-12 Migraine;Coronary artery disease; LIHC cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg06481639 chr22:41940642 POLR3H -0.67 -7.12 -0.36 6.31e-12 Vitiligo; LIHC cis rs7771547 0.573 rs566742 chr6:36395668 C/T cg07856975 chr6:36356162 ETV7 0.36 6.04 0.31 4.13e-9 Platelet distribution width; LIHC cis rs7116495 0.786 rs1894003 chr11:71750276 A/G cg26138937 chr11:71823887 C11orf51 -0.81 -8.09 -0.4 1.07e-14 Severe influenza A (H1N1) infection; LIHC cis rs61440199 0.818 rs59256081 chr3:20176778 G/A cg00235661 chr3:20228976 SGOL1 -0.43 -6.04 -0.31 3.98e-9 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs2153535 0.580 rs9379213 chr6:8474945 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs12477438 0.765 rs12468807 chr2:99691994 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.91 -0.54 1.38e-27 Chronic sinus infection; LIHC cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs6665290 0.904 rs1186 chr1:227177731 A/T cg10327440 chr1:227177885 CDC42BPA -1.19 -31.54 -0.86 3e-103 Myeloid white cell count; LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.22 0.55 9.92e-29 Prudent dietary pattern; LIHC cis rs17685 0.796 rs3757594 chr7:75678644 G/A cg01364799 chr7:75623366 TMEM120A 0.5 7.58 0.38 3.32e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6088590 0.965 rs910869 chr20:33292777 C/T cg06115741 chr20:33292138 TP53INP2 0.59 8.55 0.42 4.26e-16 Coronary artery disease; LIHC cis rs6582630 0.519 rs1851130 chr12:38507819 C/T cg13010199 chr12:38710504 ALG10B 0.44 6.01 0.31 4.73e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs6754311 0.731 rs10207652 chr2:136588478 T/A cg25344623 chr2:136566232 LCT 0.41 8.33 0.41 1.99e-15 Mosquito bite size; LIHC cis rs12477438 0.798 rs9808541 chr2:99642179 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.41 -0.53 8.75e-26 Chronic sinus infection; LIHC cis rs858239 0.712 rs200717 chr7:23392271 A/G cg00469287 chr7:23338798 C7orf30 0.45 6.21 0.32 1.54e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs611744 0.806 rs2514846 chr8:109067105 C/G cg21045802 chr8:109455806 TTC35 0.47 8.02 0.4 1.68e-14 Dupuytren's disease; LIHC cis rs4853525 0.522 rs10490538 chr2:191590066 C/T cg05765582 chr2:191677683 NA -0.29 -5.76 -0.3 1.92e-8 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC trans rs7618501 1.000 rs7618501 chr3:49772647 A/G cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs10870270 1.000 rs10870270 chr10:133754334 G/A cg26149184 chr10:133730230 NA 0.46 7.31 0.37 1.85e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1046896 0.553 rs72634343 chr17:80827392 T/C cg22027946 chr17:80790580 TBCD;ZNF750 0.52 7.5 0.38 5.69e-13 Glycated hemoglobin levels; LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs7618501 0.966 rs13085679 chr3:49869631 G/A cg21467203 chr3:49911342 NA -0.43 -7.41 -0.37 9.68e-13 Intelligence (multi-trait analysis); LIHC cis rs507080 0.885 rs533144 chr11:118559247 C/A cg04173919 chr11:118528438 PHLDB1 0.35 6.58 0.34 1.78e-10 Serum metabolite levels; LIHC trans rs1005277 0.563 rs2505215 chr10:38481273 A/G cg17830980 chr10:43048298 ZNF37B -0.52 -10.18 -0.48 2e-21 Extrinsic epigenetic age acceleration; LIHC cis rs9473924 0.542 rs9463650 chr6:50822081 C/T cg14470998 chr6:50812995 TFAP2B 0.87 9.92 0.47 1.46e-20 Body mass index; LIHC cis rs9325144 0.505 rs826893 chr12:39100536 A/G cg26384229 chr12:38710491 ALG10B -0.5 -7.91 -0.39 3.69e-14 Morning vs. evening chronotype; LIHC cis rs6466055 0.699 rs4496901 chr7:104898337 G/T cg04380332 chr7:105027541 SRPK2 0.34 6.29 0.32 9.55e-10 Schizophrenia; LIHC cis rs1775715 0.966 rs1251386 chr10:32319114 C/T cg14930904 chr10:32216787 ARHGAP12 -0.41 -7.38 -0.37 1.24e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs2153535 0.580 rs1115078 chr6:8449638 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC trans rs11098499 0.863 rs3775843 chr4:120427844 T/C cg25214090 chr10:38739885 LOC399744 0.59 9.46 0.46 5.19e-19 Corneal astigmatism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01688141 chr8:23539808 NKX3-1 0.45 6.94 0.35 1.93e-11 Cognitive function; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg03874509 chr1:107600012 PRMT6 0.73 11.41 0.53 9.01e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9790314 0.586 rs1811483 chr3:161130900 A/G cg03342759 chr3:160939853 NMD3 -0.55 -8.44 -0.42 9.41e-16 Morning vs. evening chronotype; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg26545112 chr7:97833388 LMTK2 0.38 6.53 0.33 2.37e-10 Bilirubin levels; LIHC trans rs1814175 0.791 rs10219223 chr11:49791468 A/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.79 -0.79 1.75e-74 Height; LIHC cis rs600806 0.888 rs12046539 chr1:109875415 C/T cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.25 -0.36 2.8e-12 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04517903 chr16:1557605 TELO2 0.43 6.55 0.33 2.09e-10 Longevity; LIHC cis rs11628318 0.570 rs2896450 chr14:103076595 T/C cg01864069 chr14:103024347 NA -0.47 -7.31 -0.37 1.91e-12 Platelet count; LIHC cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg18305652 chr10:134549665 INPP5A 0.51 7.95 0.39 2.82e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg11494091 chr17:61959527 GH2 0.35 5.89 0.3 9.29e-9 Height; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg22561889 chr6:118971681 C6orf204 0.55 5.94 0.31 7.13e-9 Diastolic blood pressure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05700333 chr5:131892723 RAD50 0.49 6.38 0.33 5.62e-10 Lung function (FEV1/FVC); LIHC cis rs2050392 0.792 rs684395 chr10:30719112 C/G cg25182066 chr10:30743637 MAP3K8 -0.48 -7.86 -0.39 4.93e-14 Inflammatory bowel disease; LIHC cis rs9381040 0.655 rs6939989 chr6:41020205 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.37 -6.19 -0.32 1.74e-9 Alzheimer's disease (late onset); LIHC cis rs7953508 0.506 rs12425869 chr12:93961353 A/G cg18151635 chr12:93972918 NA -0.49 -8.32 -0.41 2.06e-15 Pubertal anthropometrics; LIHC trans rs7613875 0.521 rs4688754 chr3:50074641 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.6 -0.34 1.62e-10 Body mass index; LIHC cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg06634786 chr22:41940651 POLR3H 0.73 7.56 0.38 3.67e-13 Vitiligo; LIHC cis rs8180040 0.966 rs11925823 chr3:47443065 C/G cg27129171 chr3:47204927 SETD2 0.56 9.46 0.46 5.02e-19 Colorectal cancer; LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg05368731 chr17:41323189 NBR1 0.72 12.12 0.55 2.32e-28 Menopause (age at onset); LIHC cis rs2404602 0.647 rs35940181 chr15:77180019 G/A cg03037974 chr15:76606532 NA -0.6 -10.25 -0.48 1.14e-21 Blood metabolite levels; LIHC cis rs2153535 0.580 rs2183112 chr6:8528212 G/A cg23788917 chr6:8435910 SLC35B3 0.64 9.08 0.44 8.77e-18 Motion sickness; LIHC cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg23982607 chr1:1823379 GNB1 -0.67 -13.12 -0.58 3.82e-32 Body mass index; LIHC cis rs7772486 0.875 rs9403770 chr6:146423334 C/T cg05347473 chr6:146136440 FBXO30 0.38 5.99 0.31 5.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.593 rs74760806 chr8:58024785 C/T cg20607798 chr8:58055168 NA 0.49 6.94 0.35 2.02e-11 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.774 rs73842616 chr4:120290683 G/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs9616064 0.740 rs6520049 chr22:46996309 C/T cg05621596 chr22:47072043 GRAMD4 -0.44 -6.36 -0.33 6.51e-10 Urate levels in obese individuals; LIHC cis rs3768617 0.510 rs10797851 chr1:183098001 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg09455208 chr3:40491958 NA 0.42 8.46 0.42 7.64e-16 Renal cell carcinoma; LIHC cis rs77633900 0.614 rs280014 chr15:76986890 A/G cg21673338 chr15:77095150 SCAPER -0.49 -7.52 -0.38 4.89e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs422249 0.634 rs174609 chr11:61627811 T/C cg27386326 chr11:61587980 NA 0.33 5.86 0.3 1.07e-8 Trans fatty acid levels; LIHC cis rs367615 0.704 rs4320313 chr5:108828687 A/G cg17395555 chr5:108820864 NA 0.39 8.38 0.41 1.39e-15 Colorectal cancer (SNP x SNP interaction); LIHC cis rs17685 0.672 rs1639623 chr7:75707951 A/G cg04592579 chr7:75616294 TMEM120A 0.41 7.06 0.36 9.23e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9534288 0.664 rs1926446 chr13:46629995 A/C cg15192986 chr13:46630673 CPB2 0.54 8.07 0.4 1.17e-14 Blood protein levels; LIHC trans rs78049276 0.512 rs6820938 chr4:148395903 A/G cg13149281 chr14:23389818 RBM23;PRMT5 -0.67 -10.74 -0.5 2.18e-23 Pulse pressure; LIHC trans rs7246657 0.943 rs4801759 chr19:37954985 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs561341 1.000 rs4795669 chr17:30244701 C/T cg12193833 chr17:30244370 NA -0.57 -6.01 -0.31 4.63e-9 Hip circumference adjusted for BMI; LIHC cis rs7534824 0.625 rs6676834 chr1:101463788 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.7 7.09 0.36 7.67e-12 Refractive astigmatism; LIHC cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg11890956 chr21:40555474 PSMG1 -0.51 -8.38 -0.41 1.42e-15 Cognitive function; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg02782426 chr3:40428986 ENTPD3 -0.34 -6.29 -0.32 9.67e-10 Renal cell carcinoma; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05459609 chr16:4689950 MGRN1 -0.4 -6.14 -0.32 2.29e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 0.721 rs28442079 chr1:46172001 A/G cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7264396 0.623 rs6060504 chr20:34197619 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -8.73 -0.43 1.11e-16 Total cholesterol levels; LIHC cis rs67478160 0.619 rs1187416 chr14:104311465 A/G cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.49 -0.38 5.81e-13 Schizophrenia; LIHC cis rs909002 0.800 rs6703093 chr1:32093561 C/T cg13919466 chr1:32135498 COL16A1 -0.35 -6.59 -0.34 1.7e-10 Intelligence (multi-trait analysis); LIHC trans rs11039798 0.588 rs12294395 chr11:48476860 C/T cg15704280 chr7:45808275 SEPT13 0.6 6.63 0.34 1.33e-10 Axial length; LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg22907277 chr7:1156413 C7orf50 0.51 7.87 0.39 4.76e-14 Longevity;Endometriosis; LIHC cis rs244293 0.965 rs244305 chr17:53237843 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.19 -0.36 4.2e-12 Menarche (age at onset); LIHC cis rs7412746 0.658 rs3768015 chr1:150812954 C/T cg17724175 chr1:150552817 MCL1 0.49 9.54 0.46 2.85e-19 Melanoma; LIHC cis rs727505 0.909 rs1031958 chr7:124627309 C/T cg23710748 chr7:124431027 NA -0.34 -5.93 -0.31 7.5e-9 Lewy body disease; LIHC cis rs4332037 0.722 rs4719331 chr7:1914679 A/C cg23043544 chr7:2124092 MAD1L1 -0.42 -6.3 -0.32 9.06e-10 Bipolar disorder; LIHC cis rs12887734 0.546 rs12886637 chr14:104222892 A/G cg08213375 chr14:104286397 PPP1R13B -0.52 -9.09 -0.44 8.05e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs1552244 0.572 rs59074548 chr3:10164347 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs600806 0.745 rs4246517 chr1:110007636 G/C cg23091122 chr1:110024289 SYPL2 -0.48 -6.42 -0.33 4.59e-10 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.903 rs7970390 chr12:29398655 A/G cg14222432 chr12:29376421 FAR2 0.37 7.23 0.36 3.27e-12 QT interval; LIHC cis rs7395581 0.918 rs4752825 chr11:47352409 G/A cg26139080 chr11:47293733 MADD -0.5 -8.45 -0.42 8.74e-16 HDL cholesterol; LIHC cis rs6426558 0.514 rs3754418 chr1:227348473 T/C cg10327440 chr1:227177885 CDC42BPA -0.45 -6.96 -0.35 1.72e-11 Neutrophil percentage of white cells; LIHC cis rs67460515 0.596 rs35589595 chr3:160930984 G/A cg17135325 chr3:160939158 NMD3 0.6 8.73 0.43 1.12e-16 Parkinson's disease; LIHC cis rs67460515 0.892 rs7610985 chr3:161062848 G/A cg03342759 chr3:160939853 NMD3 -0.55 -7.91 -0.39 3.54e-14 Parkinson's disease; LIHC cis rs7408868 0.908 rs62113794 chr19:15277337 C/A cg09752223 chr19:15281200 NOTCH3 -0.37 -5.83 -0.3 1.28e-8 Pulse pressure; LIHC cis rs67981189 0.593 rs2526871 chr14:71385113 G/A cg15816911 chr14:71606274 NA -0.41 -6.44 -0.33 4.01e-10 Schizophrenia; LIHC cis rs8060686 0.516 rs7187202 chr16:68273895 T/C cg05110241 chr16:68378359 PRMT7 -0.55 -6.46 -0.33 3.63e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg17328964 chr8:145687451 CYHR1 0.46 7.51 0.38 5.17e-13 Age at first birth; LIHC cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg16145915 chr7:1198662 ZFAND2A -0.37 -9.4 -0.45 7.85e-19 Longevity;Endometriosis; LIHC cis rs10089 1.000 rs6595800 chr5:127411647 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.85 0.35 3.45e-11 Ileal carcinoids; LIHC cis rs7944584 0.563 rs2280231 chr11:47600438 C/T cg20307385 chr11:47447363 PSMC3 0.9 12.62 0.56 3.02e-30 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2070488 0.931 rs7630012 chr3:38552250 A/G cg24069376 chr3:38537580 EXOG -0.38 -6.99 -0.35 1.41e-11 Electrocardiographic conduction measures; LIHC cis rs4148883 0.689 rs2602861 chr4:100030896 C/T cg12011299 chr4:100065546 ADH4 0.37 7.39 0.37 1.14e-12 Alcohol dependence; LIHC cis rs12079745 0.590 rs2280257 chr1:169352787 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 2.01e-11 QT interval; LIHC cis rs899997 1.000 rs4887078 chr15:79011073 C/T cg04896959 chr15:78267971 NA 0.4 7.88 0.39 4.52e-14 Coronary artery disease or large artery stroke; LIHC cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.11 -0.61 6.26e-36 Alzheimer's disease; LIHC cis rs17433710 0.516 rs11805556 chr1:162673946 C/T cg01063088 chr1:162760584 HSD17B7 -0.44 -6.38 -0.33 5.76e-10 Dupuytren's disease; LIHC cis rs4808199 0.948 rs757001 chr19:19448808 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.56 8.12 0.4 8.8e-15 Nonalcoholic fatty liver disease; LIHC cis rs778371 0.723 rs6704763 chr2:233592487 C/T cg08000102 chr2:233561755 GIGYF2 0.88 14.81 0.63 1.09e-38 Schizophrenia; LIHC cis rs9543976 1.000 rs9543976 chr13:76136648 G/A cg01531495 chr13:76123901 UCHL3 0.5 6.19 0.32 1.71e-9 Diabetic retinopathy; LIHC cis rs67981189 0.593 rs2810074 chr14:71378533 G/A cg15816911 chr14:71606274 NA -0.42 -6.75 -0.34 6.28e-11 Schizophrenia; LIHC cis rs7301016 0.846 rs11174569 chr12:63021161 A/C cg11441379 chr12:63026424 NA 0.63 6.28 0.32 1.01e-9 IgG glycosylation; LIHC cis rs6089829 0.962 rs4997812 chr20:61663153 T/G cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs17685 0.753 rs4398845 chr7:75716781 G/A cg04592579 chr7:75616294 TMEM120A 0.38 6.55 0.33 2.17e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2637266 0.783 rs720249 chr10:78476143 T/C cg18941641 chr10:78392320 NA 0.28 6.04 0.31 3.98e-9 Pulmonary function; LIHC trans rs9951602 0.512 rs73494176 chr18:76644895 T/C cg02800362 chr5:177631904 HNRNPAB 0.66 10.44 0.49 2.51e-22 Obesity-related traits; LIHC cis rs10508774 0.925 rs11008955 chr10:32805202 G/A cg01819863 chr10:32635814 EPC1 0.65 6.03 0.31 4.19e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9911578 1.000 rs4636974 chr17:56965373 C/G cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs4764487 0.735 rs2159521 chr12:6349328 A/G cg08284733 chr12:6341482 CD9 0.37 6.55 0.33 2.07e-10 Mean platelet volume; LIHC trans rs875971 0.545 rs13311962 chr7:66068129 C/T cg26939375 chr7:64535504 NA -0.39 -6.19 -0.32 1.7e-9 Aortic root size; LIHC cis rs950169 1.000 rs34751999 chr15:84758419 T/C cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs9486719 1.000 rs28623445 chr6:96899116 G/T cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.32e-12 Migraine;Coronary artery disease; LIHC cis rs10870270 0.956 rs10870293 chr10:133771413 G/A cg08754478 chr10:133766260 PPP2R2D -0.53 -7.76 -0.39 9.88e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 3.15e-30 Menopause (age at onset); LIHC cis rs4755351 0.553 rs11032154 chr11:33155264 A/G cg05567920 chr11:33183001 CSTF3 0.42 6.21 0.32 1.56e-9 Lung cancer in ever smokers; LIHC cis rs57502260 0.764 rs3867143 chr11:68223074 A/G cg16797656 chr11:68205561 LRP5 0.59 7.98 0.4 2.22e-14 Total body bone mineral density (age 45-60); LIHC cis rs11960470 1.000 rs11960470 chr5:50328257 A/C cg06027927 chr5:50259733 NA 0.57 8.2 0.41 4.94e-15 Breast cancer; LIHC trans rs11039100 0.681 rs11039170 chr11:5845187 T/G cg11650987 chr12:10280440 CLEC7A 0.41 6.21 0.32 1.51e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.79 0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs7618501 0.669 rs3774758 chr3:49938227 C/G cg21467203 chr3:49911342 NA -0.49 -8.59 -0.42 3.1e-16 Intelligence (multi-trait analysis); LIHC cis rs5758511 0.680 rs739146 chr22:42660414 A/G cg20195005 chr22:42527684 CYP2D6 0.31 5.85 0.3 1.14e-8 Birth weight; LIHC cis rs7223966 1.000 rs7216798 chr17:61740963 G/A cg05941027 chr17:61774174 LIMD2 0.3 5.97 0.31 5.91e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7223966 1.000 rs28463311 chr17:61919643 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 6.83 0.35 3.83e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg16497277 chr3:49208875 KLHDC8B 0.48 6.07 0.31 3.47e-9 Menarche (age at onset); LIHC cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg26116260 chr4:7069785 GRPEL1 0.98 17.99 0.7 2.1e-51 Monocyte percentage of white cells; LIHC cis rs6500602 0.727 rs4786515 chr16:4578133 T/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 5.85 0.3 1.17e-8 Schizophrenia; LIHC cis rs655641 1.000 rs548121 chr11:85675533 C/T cg09030501 chr11:85779252 PICALM -0.5 -5.9 -0.3 8.84e-9 Platelet count; LIHC cis rs1008375 1.000 rs4235388 chr4:17682030 G/A cg02297831 chr4:17616191 MED28 0.41 6.66 0.34 1.08e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs611744 0.647 rs11774904 chr8:109273435 G/A cg18478394 chr8:109455254 TTC35 0.41 7.18 0.36 4.44e-12 Dupuytren's disease; LIHC cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg15691649 chr6:25882328 NA -0.55 -7.06 -0.36 9.22e-12 Intelligence (multi-trait analysis); LIHC trans rs208520 0.526 rs9354370 chr6:66808209 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.02 19.82 0.73 9.57e-59 Exhaled nitric oxide output; LIHC cis rs2742417 0.587 rs2742375 chr3:45784602 G/A cg04837898 chr3:45731254 SACM1L -0.5 -8.36 -0.41 1.55e-15 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs9790314 0.503 rs6441374 chr3:161064540 A/T cg03342759 chr3:160939853 NMD3 -0.53 -7.61 -0.38 2.62e-13 Morning vs. evening chronotype; LIHC cis rs2404602 0.692 rs35498563 chr15:76958868 C/T cg03037974 chr15:76606532 NA 0.75 14.57 0.62 9.92e-38 Blood metabolite levels; LIHC cis rs2479724 0.846 rs2254474 chr6:41843044 T/G cg17623882 chr6:41773611 USP49 -0.55 -8.8 -0.43 6.67e-17 Menarche (age at onset); LIHC cis rs735396 0.595 rs1169279 chr12:121455873 C/T cg25281562 chr12:121454272 C12orf43 0.45 7.92 0.39 3.41e-14 N-glycan levels; LIHC cis rs7552404 1.000 rs12091720 chr1:76186949 G/A cg03433033 chr1:76189801 ACADM 0.66 9.42 0.45 6.76e-19 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05787890 chr3:183165321 NA 0.49 6.55 0.33 2.15e-10 Lung function (FEV1/FVC); LIHC cis rs600806 0.821 rs1030522 chr1:109900707 C/G cg23091122 chr1:110024289 SYPL2 -0.48 -6.39 -0.33 5.44e-10 Intelligence (multi-trait analysis); LIHC cis rs8016982 0.657 rs11625861 chr14:81735001 C/T cg01989461 chr14:81687754 GTF2A1 -0.62 -12.23 -0.55 8.88e-29 Schizophrenia; LIHC cis rs507080 0.733 rs570949 chr11:118571911 G/T cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs10911232 0.507 rs5022057 chr1:182997761 T/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12078486 chr1:155108334 RAG1AP1 0.43 6.28 0.32 1.03e-9 Lung function (FEV1/FVC); LIHC cis rs10751667 0.643 rs7396623 chr11:934104 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.81 -0.63 1.06e-38 Alzheimer's disease (late onset); LIHC cis rs6860806 0.661 rs28472559 chr5:131581611 G/A cg24060327 chr5:131705240 SLC22A5 -0.45 -5.75 -0.3 2.03e-8 Breast cancer; LIHC cis rs8017423 0.935 rs7160304 chr14:90752908 G/T cg14092571 chr14:90743983 NA -0.42 -6.54 -0.33 2.27e-10 Mortality in heart failure; LIHC cis rs8180040 0.627 rs58956475 chr3:47224615 G/C cg27129171 chr3:47204927 SETD2 -0.58 -9.61 -0.46 1.62e-19 Colorectal cancer; LIHC cis rs477692 0.967 rs496692 chr10:131429100 C/T cg19680672 chr10:131412579 MGMT -0.46 -7.07 -0.36 8.74e-12 Response to temozolomide; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00966380 chr12:47633443 NA -0.52 -6.96 -0.35 1.77e-11 Lung function (FEV1/FVC); LIHC cis rs17433710 0.516 rs4477251 chr1:162670541 A/G cg01063088 chr1:162760584 HSD17B7 0.43 6.15 0.32 2.22e-9 Dupuytren's disease; LIHC cis rs67311347 1.000 rs4973878 chr3:40407565 C/T cg00656387 chr3:40428638 ENTPD3 0.41 6.87 0.35 3.07e-11 Renal cell carcinoma; LIHC cis rs9381040 0.655 rs6939989 chr6:41020205 A/G cg03644281 chr6:41068752 NFYA;LOC221442 -0.38 -5.82 -0.3 1.34e-8 Alzheimer's disease (late onset); LIHC trans rs12478296 1.000 rs56387669 chr2:243043889 T/C cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.92e-15 Obesity-related traits; LIHC cis rs6121246 0.909 rs6060633 chr20:30263317 G/T cg13852791 chr20:30311386 BCL2L1 0.97 9.8 0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs4906332 1.000 rs35126287 chr14:103959432 A/G cg19000871 chr14:103996768 TRMT61A -0.46 -7.86 -0.39 5.04e-14 Coronary artery disease; LIHC cis rs1577917 1.000 rs10455158 chr6:86672825 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.06 -0.48 5.08e-21 Response to antipsychotic treatment; LIHC cis rs17345786 0.520 rs12638134 chr3:101334609 G/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.37 5.85 0.3 1.16e-8 Colonoscopy-negative controls vs population controls; LIHC trans rs2727020 0.521 rs10839296 chr11:49537617 T/C cg03929089 chr4:120376271 NA 0.69 10.06 0.48 4.94e-21 Coronary artery disease; LIHC cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg23172400 chr8:95962367 TP53INP1 -0.35 -7.83 -0.39 6.02e-14 Type 2 diabetes; LIHC trans rs1005277 0.579 rs1780115 chr10:38524773 C/T cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg01448562 chr3:133502909 NA -0.42 -6.53 -0.33 2.37e-10 Iron status biomarkers; LIHC cis rs1506636 0.924 rs2402668 chr7:123296605 T/A cg03229431 chr7:123269106 ASB15 -0.61 -12.04 -0.55 4.49e-28 Plateletcrit;Platelet count; LIHC cis rs9394841 0.692 rs9369312 chr6:41841535 A/T cg17623882 chr6:41773611 USP49 -0.44 -5.89 -0.3 9.01e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs61041384 1.000 rs76872194 chr12:123693363 C/A cg00376283 chr12:123451042 ABCB9 -0.54 -5.89 -0.3 9.21e-9 Schizophrenia; LIHC cis rs9896052 0.614 rs9890461 chr17:73452479 G/A cg25649188 chr17:73499917 CASKIN2 0.46 6.91 0.35 2.34e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs870825 0.929 rs10015218 chr4:185589789 T/C cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs4308124 0.708 rs6749633 chr2:111988016 A/G cg04571233 chr2:111982156 NA 0.5 6.25 0.32 1.19e-9 Vitiligo; LIHC cis rs965469 0.901 rs6037563 chr20:3326568 G/A cg25506879 chr20:3388711 C20orf194 -0.58 -6.98 -0.35 1.59e-11 IFN-related cytopenia; LIHC cis rs10779751 0.666 rs77270747 chr1:11214584 A/C cg08854313 chr1:11322531 MTOR -0.82 -12.35 -0.56 3.06e-29 Body mass index; LIHC cis rs10504229 0.906 rs2270607 chr8:58194699 A/G cg02290350 chr8:58132656 NA 0.44 8.95 0.44 2.3e-17 Developmental language disorder (linguistic errors); LIHC cis rs40363 0.645 rs250631 chr16:3523215 G/C cg22508957 chr16:3507546 NAT15 0.49 8.73 0.43 1.16e-16 Tuberculosis; LIHC cis rs1046896 0.628 rs12452314 chr17:80723362 A/G cg02711726 chr17:80685570 FN3KRP -0.5 -9.38 -0.45 9.09e-19 Glycated hemoglobin levels; LIHC cis rs9902453 0.578 rs8073217 chr17:28164263 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 13.66 0.59 3.29e-34 Coffee consumption (cups per day); LIHC cis rs7927771 0.864 rs11604680 chr11:47457539 A/G cg18512352 chr11:47633146 NA -0.25 -5.8 -0.3 1.49e-8 Subjective well-being; LIHC cis rs1552244 0.816 rs56387520 chr3:10042782 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs600806 0.888 rs461200 chr1:109855404 G/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.11 -0.36 6.85e-12 Intelligence (multi-trait analysis); LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg07234388 chr1:156261841 TMEM79 0.51 9.08 0.44 8.56e-18 Tonsillectomy; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg09455208 chr3:40491958 NA 0.4 8.06 0.4 1.33e-14 Renal cell carcinoma; LIHC cis rs7726839 0.540 rs12517638 chr5:645484 C/T cg09021430 chr5:549028 NA -0.41 -8.36 -0.41 1.56e-15 Obesity-related traits; LIHC cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.1 -0.48 3.53e-21 Platelet count; LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg22281195 chr17:26989129 SUPT6H;SDF2 -0.37 -6.17 -0.32 1.96e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11864453 0.713 rs9926156 chr16:72142895 G/C cg16558253 chr16:72132732 DHX38 -0.51 -8.24 -0.41 3.65e-15 Fibrinogen levels; LIHC cis rs6456156 0.524 rs6934043 chr6:167466449 C/T cg07741184 chr6:167504864 NA 0.29 7.05 0.36 1.02e-11 Primary biliary cholangitis; LIHC cis rs4663866 0.803 rs71426511 chr2:239180200 G/A cg16914508 chr2:239161102 PER2 0.8 5.9 0.3 8.78e-9 Irritable bowel syndrome; LIHC cis rs7927771 0.832 rs10838704 chr11:47424717 T/C cg20135002 chr11:47629003 NA -0.59 -10.11 -0.48 3.4e-21 Subjective well-being; LIHC cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg18357526 chr6:26021779 HIST1H4A 0.97 14.2 0.61 2.61e-36 Intelligence (multi-trait analysis); LIHC cis rs9303280 0.806 rs2305480 chr17:38062196 G/A cg11212589 chr17:38028394 ZPBP2 0.36 7.24 0.36 3.07e-12 Self-reported allergy; LIHC trans rs35110281 0.807 rs9984002 chr21:45061501 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.22 0.32 1.49e-9 Mean corpuscular volume; LIHC cis rs7520050 0.902 rs4638056 chr1:46458153 T/G cg03146154 chr1:46216737 IPP -0.38 -6.27 -0.32 1.11e-9 Red blood cell count;Reticulocyte count; LIHC cis rs208520 0.770 rs2224422 chr6:66883993 G/A cg07460842 chr6:66804631 NA -0.76 -8.34 -0.41 1.89e-15 Exhaled nitric oxide output; LIHC cis rs7223966 1.000 rs11079511 chr17:61858537 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.72 0.34 7.53e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs365132 0.875 rs353491 chr5:176432947 C/G cg16309518 chr5:176445507 NA -0.54 -10.26 -0.49 1.03e-21 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs12765878 1.000 rs1980653 chr10:105654164 A/G cg11005552 chr10:105648138 OBFC1 0.38 6.04 0.31 4.07e-9 Coronary artery disease; LIHC cis rs2842992 0.724 rs9347340 chr6:160188891 C/T cg26839252 chr6:160211577 TCP1;MRPL18 -0.38 -6.73 -0.34 7.05e-11 Age-related macular degeneration (geographic atrophy); LIHC cis rs7520050 0.966 rs1707321 chr1:46505309 A/G cg03146154 chr1:46216737 IPP -0.36 -5.97 -0.31 5.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs67311347 0.911 rs6773917 chr3:40469254 G/T cg00656387 chr3:40428638 ENTPD3 0.4 6.78 0.34 5.24e-11 Renal cell carcinoma; LIHC cis rs10242455 0.702 rs59240302 chr7:99072991 C/G cg18809830 chr7:99032528 PTCD1 -0.83 -6.45 -0.33 3.72e-10 Blood metabolite levels; LIHC cis rs3540 0.512 rs3862433 chr15:91076028 G/A cg22089800 chr15:90895588 ZNF774 -0.52 -7.35 -0.37 1.47e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2976388 0.647 rs2244163 chr8:143784500 T/G cg13446199 chr8:143762866 PSCA -0.2 -5.74 -0.3 2.05e-8 Urinary tract infection frequency; LIHC cis rs155076 1.000 rs261404 chr13:21858162 T/G cg14456004 chr13:21872349 NA -1.03 -11.33 -0.52 1.72e-25 White matter hyperintensity burden; LIHC cis rs2836974 0.583 rs9636957 chr21:40705847 G/A cg17971929 chr21:40555470 PSMG1 -0.43 -6.32 -0.32 8.01e-10 Cognitive function; LIHC cis rs4808199 0.895 rs10421505 chr19:19459554 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.54 7.99 0.4 2.12e-14 Nonalcoholic fatty liver disease; LIHC cis rs6503525 0.701 rs28618095 chr17:38109075 T/C cg17467752 chr17:38218738 THRA 0.4 5.86 0.3 1.07e-8 Asthma; LIHC cis rs2976388 0.609 rs2585152 chr8:143786214 A/T cg06565975 chr8:143823917 SLURP1 0.34 6.57 0.33 1.84e-10 Urinary tract infection frequency; LIHC cis rs736408 0.583 rs2710323 chr3:52815905 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.4 6.63 0.34 1.3e-10 Bipolar disorder; LIHC cis rs11608355 0.545 rs9943764 chr12:109905720 G/A cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg06481639 chr22:41940642 POLR3H -0.71 -7.13 -0.36 5.83e-12 Vitiligo; LIHC cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.17 -0.32 1.88e-9 Aortic root size; LIHC cis rs17102423 0.685 rs4899161 chr14:65540901 G/A cg11161011 chr14:65562177 MAX -0.45 -6.68 -0.34 9.51e-11 Obesity-related traits; LIHC cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg13047869 chr3:10149882 C3orf24 0.5 5.92 0.3 7.91e-9 Alzheimer's disease; LIHC cis rs3008870 0.958 rs12131222 chr1:67438535 A/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs523522 0.962 rs3893104 chr12:120903936 G/A cg27279351 chr12:120934652 DYNLL1 0.66 11.71 0.53 7.54e-27 High light scatter reticulocyte count; LIHC cis rs1862618 0.671 rs2591968 chr5:56233541 A/G cg24531977 chr5:56204891 C5orf35 -0.54 -7.9 -0.39 3.93e-14 Initial pursuit acceleration; LIHC cis rs921968 0.643 rs711186 chr2:219346102 A/G cg18887096 chr2:219472410 PLCD4 -0.36 -6.19 -0.32 1.73e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg19318889 chr4:1322082 MAEA 0.62 9.8 0.47 3.91e-20 Longevity; LIHC cis rs6860806 0.507 rs635619 chr5:131720265 G/A cg24060327 chr5:131705240 SLC22A5 0.79 12.39 0.56 2.31e-29 Breast cancer; LIHC cis rs6089829 1.000 rs6089829 chr20:61669036 C/T cg03213289 chr20:61660250 NA -0.45 -7.89 -0.39 4.24e-14 Prostate cancer (SNP x SNP interaction); LIHC cis rs9534288 0.797 rs2104515 chr13:46569846 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs1577917 0.958 rs10455448 chr6:86533611 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.11 -0.4 8.96e-15 Response to antipsychotic treatment; LIHC trans rs5756813 0.646 rs875300 chr22:38157805 A/G cg19894588 chr14:64061835 NA 0.45 6.48 0.33 3.29e-10 Optic cup area;Vertical cup-disc ratio; LIHC cis rs1949733 0.523 rs16842557 chr4:8543985 C/T cg11789530 chr4:8429930 ACOX3 -0.57 -7.93 -0.39 3.06e-14 Response to antineoplastic agents; LIHC cis rs2439831 0.850 rs28595038 chr15:44044859 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.52 0.33 2.46e-10 Lung cancer in ever smokers; LIHC cis rs2290416 0.584 rs3816477 chr8:144685271 T/C cg17524265 chr8:144659883 NAPRT1 -0.58 -6.32 -0.32 8.31e-10 Attention deficit hyperactivity disorder; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg06873352 chr17:61820015 STRADA 0.72 12.72 0.57 1.29e-30 Prudent dietary pattern; LIHC cis rs785830 0.523 rs2484966 chr9:216493 T/C cg14500300 chr9:211689 NA 0.28 6.41 0.33 4.95e-10 Platelet distribution width; LIHC cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg10295955 chr4:187884368 NA 1.0 22.77 0.78 1.74e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs72781680 1.000 rs7578969 chr2:24168620 T/C cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs735860 0.726 rs209517 chr6:53206989 A/T cg10236188 chr6:53219634 NA 0.41 7.58 0.38 3.22e-13 Glaucoma; LIHC cis rs2108622 0.727 rs7254940 chr19:15984508 C/T cg13772218 chr19:15982569 NA 0.37 7.68 0.38 1.72e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg19318889 chr4:1322082 MAEA -0.47 -7.74 -0.39 1.14e-13 Obesity-related traits; LIHC cis rs8103278 0.507 rs3745802 chr19:46271177 G/T cg14061069 chr19:46274453 DMPK 0.68 12.69 0.57 1.75e-30 Coronary artery disease; LIHC cis rs1152591 0.792 rs1152595 chr14:64674981 T/C cg23250157 chr14:64679961 SYNE2 0.4 5.89 0.3 9.34e-9 Atrial fibrillation; LIHC cis rs11888559 0.655 rs4297863 chr2:204005877 T/C cg24605529 chr2:203879461 NBEAL1 0.78 5.92 0.31 7.62e-9 Height; LIHC cis rs7552404 1.000 rs12123977 chr1:76209754 A/G cg10523679 chr1:76189770 ACADM -0.53 -6.87 -0.35 3.01e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1577917 1.000 rs12200330 chr6:86656653 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.32 -0.49 6.45e-22 Response to antipsychotic treatment; LIHC cis rs7534824 0.625 rs17409422 chr1:101502386 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.73 7.28 0.37 2.38e-12 Refractive astigmatism; LIHC cis rs36051895 0.664 rs3780369 chr9:5095095 A/C cg02405213 chr9:5042618 JAK2 -0.66 -11.01 -0.51 2.46e-24 Pediatric autoimmune diseases; LIHC cis rs7903847 0.642 rs4635018 chr10:99137839 C/G cg20016023 chr10:99160130 RRP12 0.41 6.22 0.32 1.42e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs432925 0.529 rs9925945 chr16:393564 A/C cg26944245 chr16:421049 TMEM8A;MRPL28 0.44 6.36 0.33 6.41e-10 Morning vs. evening chronotype; LIHC cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg19318889 chr4:1322082 MAEA 0.63 10.28 0.49 8.83e-22 Longevity; LIHC cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.69 0.34 9.33e-11 Bipolar disorder; LIHC cis rs35362007 0.530 rs11621250 chr14:96011442 C/T cg02940042 chr14:96000874 GLRX5;SNHG10;SCARNA13 0.74 6.33 0.32 7.53e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs11671005 0.693 rs11666928 chr19:58914231 A/G cg25952890 chr19:58913133 NA 0.7 7.19 0.36 4.02e-12 Mean platelet volume; LIHC trans rs8002861 0.870 rs9525855 chr13:44431660 A/G cg17145862 chr1:211918768 LPGAT1 0.58 10.69 0.5 3.2e-23 Leprosy; LIHC cis rs757110 0.705 rs10832778 chr11:17394073 C/G cg15432903 chr11:17409602 KCNJ11 0.65 10.11 0.48 3.36e-21 Type 2 diabetes; LIHC cis rs4803468 1.000 rs878082 chr19:41897674 G/A cg09537434 chr19:41945824 ATP5SL -0.98 -20.06 -0.74 1.03e-59 Height; LIHC cis rs6840360 1.000 rs10019048 chr4:152603615 A/G cg22705602 chr4:152727874 NA -0.32 -6.61 -0.34 1.45e-10 Intelligence (multi-trait analysis); LIHC cis rs782590 0.557 rs7592219 chr2:55887176 T/C cg03859395 chr2:55845619 SMEK2 -0.47 -7.56 -0.38 3.63e-13 Metabolic syndrome; LIHC cis rs6785206 0.667 rs2253125 chr3:128329793 T/C cg16766828 chr3:128327626 NA -0.5 -5.87 -0.3 1.03e-8 Lymphocyte percentage of white cells; LIHC cis rs8062405 1.000 rs12325113 chr16:28848668 T/C cg16576597 chr16:28551801 NUPR1 0.37 5.83 0.3 1.26e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1552244 0.882 rs9757159 chr3:10039166 C/T cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs9640161 0.789 rs3735172 chr7:150028958 C/T cg10018233 chr7:150070692 REPIN1 -0.55 -9.34 -0.45 1.3e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs6076065 0.594 rs6048755 chr20:23337233 A/G cg11657817 chr20:23433608 CST11 0.32 6.74 0.34 6.87e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs9916302 0.851 rs9909064 chr17:37500434 G/T cg00129232 chr17:37814104 STARD3 0.38 6.15 0.32 2.21e-9 Glomerular filtration rate (creatinine); LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.68 0.38 1.68e-13 Height; LIHC cis rs7772486 0.754 rs10872580 chr6:146140281 C/T cg05347473 chr6:146136440 FBXO30 -0.41 -6.72 -0.34 7.77e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs911555 0.755 rs10148970 chr14:103892000 G/A cg17675199 chr6:35436792 RPL10A 0.39 7.87 0.39 4.66e-14 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.798 rs13414153 chr2:99624748 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -8.61 -0.42 2.65e-16 Chronic sinus infection; LIHC cis rs9649213 0.614 rs12539761 chr7:98013839 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.56 -9.89 -0.47 1.87e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs8010715 0.816 rs6573572 chr14:24599230 C/A cg23112188 chr14:24563095 PCK2 -0.29 -6.08 -0.31 3.25e-9 IgG glycosylation; LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.84 0.78 8.76e-71 Height; LIHC cis rs4925386 0.808 rs1760073 chr20:60926106 A/G cg24112000 chr20:60950667 NA 0.44 7.04 0.36 1.09e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs6793245 0.845 rs4073797 chr3:38590850 A/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.47 -6.94 -0.35 2.01e-11 QT interval; LIHC cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg24531977 chr5:56204891 C5orf35 -0.68 -9.88 -0.47 1.99e-20 Initial pursuit acceleration; LIHC cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg18357526 chr6:26021779 HIST1H4A -0.43 -6.14 -0.32 2.26e-9 Blood metabolite levels; LIHC cis rs11630290 0.592 rs12324556 chr15:64160951 G/A cg12036633 chr15:63758958 NA 0.64 6.84 0.35 3.69e-11 Iris characteristics; LIHC cis rs7100689 0.646 rs1290317 chr10:82062531 C/A cg00277334 chr10:82204260 NA -0.6 -7.53 -0.38 4.49e-13 Post bronchodilator FEV1; LIHC cis rs9921222 0.521 rs9935268 chr16:381562 G/C cg26944245 chr16:421049 TMEM8A;MRPL28 0.41 7.01 0.35 1.27e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.25 0.61 1.74e-36 Prudent dietary pattern; LIHC cis rs600806 0.778 rs4970731 chr1:109995459 T/C cg23091122 chr1:110024289 SYPL2 -0.49 -6.43 -0.33 4.39e-10 Intelligence (multi-trait analysis); LIHC cis rs6598955 0.724 rs12757113 chr1:26597144 C/T cg00852783 chr1:26633632 UBXN11 0.54 8.8 0.43 7.12e-17 Obesity-related traits; LIHC cis rs10870270 1.000 rs10781564 chr10:133757922 A/G cg17892150 chr10:133769511 PPP2R2D -0.69 -12.96 -0.57 1.56e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2257205 0.667 rs8070407 chr17:56709172 G/A cg05425664 chr17:57184151 TRIM37 -0.61 -6.84 -0.35 3.67e-11 Pancreatic cancer; LIHC trans rs7246657 1.000 rs10426297 chr19:37798373 A/G cg10208301 chr11:6592745 DNHD1 0.48 6.35 0.32 6.68e-10 Coronary artery calcification; LIHC cis rs74417235 0.684 rs7723312 chr5:154053249 A/G cg25588787 chr5:154027256 NA -0.38 -5.71 -0.3 2.42e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs2050392 0.767 rs10763786 chr10:30693567 G/C cg25182066 chr10:30743637 MAP3K8 0.6 9.64 0.46 1.28e-19 Inflammatory bowel disease; LIHC cis rs782590 0.935 rs2586954 chr2:55892261 A/C cg03859395 chr2:55845619 SMEK2 0.82 14.14 0.61 4.43e-36 Metabolic syndrome; LIHC cis rs61677309 0.638 rs17122021 chr11:118145686 C/T cg06090739 chr11:118230722 UBE4A 0.33 6.22 0.32 1.42e-9 Lung cancer in ever smokers; LIHC cis rs921968 0.643 rs600057 chr2:219456737 A/G cg18887096 chr2:219472410 PLCD4 0.36 6.32 0.32 8.27e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs12022452 0.591 rs1001400 chr1:40998902 A/G cg25568243 chr1:40974465 DEM1 0.45 5.93 0.31 7.35e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2243480 1.000 rs431318 chr7:65511597 G/A cg10756647 chr7:56101905 PSPH 1.08 13.46 0.59 2e-33 Diabetic kidney disease; LIHC cis rs881375 0.935 rs7034390 chr9:123646488 A/T cg14580859 chr9:123691850 NA 0.36 6.22 0.32 1.45e-9 Rheumatoid arthritis; LIHC cis rs6061231 0.583 rs2427313 chr20:60970675 G/A cg03945807 chr20:60948434 NA 0.38 6.2 0.32 1.61e-9 Colorectal cancer; LIHC cis rs908922 0.676 rs7532535 chr1:152517597 T/A cg20991723 chr1:152506922 NA 0.53 9.23 0.45 2.89e-18 Hair morphology; LIHC cis rs875971 0.543 rs801191 chr7:66032955 G/A cg18876405 chr7:65276391 NA -0.4 -7.3 -0.37 2.08e-12 Aortic root size; LIHC cis rs34779708 0.771 rs3867218 chr10:35527543 T/C cg03585969 chr10:35415529 CREM 0.79 11.51 0.53 3.97e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6815814 0.861 rs12233670 chr4:38787216 C/T cg06935464 chr4:38784597 TLR10 0.52 9.14 0.44 5.5e-18 Breast cancer; LIHC cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg02891314 chr5:179741120 GFPT2 -0.45 -6.09 -0.31 3.04e-9 Height; LIHC cis rs7940866 0.838 rs12790299 chr11:130803634 A/G cg12179176 chr11:130786555 SNX19 0.68 10.08 0.48 4.19e-21 Schizophrenia; LIHC cis rs919433 0.653 rs700651 chr2:198631714 G/A cg00792783 chr2:198669748 PLCL1 0.45 6.47 0.33 3.45e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs769267 1.000 rs769267 chr19:19446936 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.23 0.32 1.35e-9 Tonsillectomy; LIHC trans rs9929218 1.000 rs12921546 chr16:68780069 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -9.13 -0.44 6.05e-18 Colorectal cancer; LIHC cis rs7845219 0.544 rs10956930 chr8:95919786 C/G cg16049864 chr8:95962084 TP53INP1 -0.43 -6.43 -0.33 4.27e-10 Type 2 diabetes; LIHC cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg09323728 chr8:95962352 TP53INP1 -0.29 -6.26 -0.32 1.18e-9 Type 2 diabetes; LIHC cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg12463550 chr7:65579703 CRCP 0.67 7.06 0.36 9.33e-12 Diabetic kidney disease; LIHC cis rs7572733 0.534 rs700681 chr2:198711502 C/A cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs7618501 0.633 rs6792892 chr3:49995518 T/C cg24110177 chr3:50126178 RBM5 -0.48 -7.78 -0.39 8.7e-14 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.505 rs200936 chr10:38134935 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.47 -0.33 3.34e-10 Extrinsic epigenetic age acceleration; LIHC cis rs910316 0.763 rs4556 chr14:75476071 G/C cg11812906 chr14:75593930 NEK9 0.72 13.25 0.58 1.31e-32 Height; LIHC cis rs6456156 0.586 rs13210649 chr6:167473193 T/G cg23791538 chr6:167370224 RNASET2 -0.61 -10.39 -0.49 3.77e-22 Primary biliary cholangitis; LIHC cis rs7020830 0.858 rs13293465 chr9:37127678 C/T cg14294708 chr9:37120828 ZCCHC7 1.16 26.23 0.82 7.21e-84 Schizophrenia; LIHC cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg03264133 chr6:25882463 NA -0.61 -8.65 -0.42 2.08e-16 Blood metabolite levels; LIHC cis rs6430585 0.528 rs309151 chr2:136661150 C/T cg15123519 chr2:136567270 LCT -0.36 -5.75 -0.3 2.01e-8 Corneal structure; LIHC trans rs11098499 0.955 rs4145951 chr4:120155817 A/G cg25214090 chr10:38739885 LOC399744 0.54 8.2 0.41 4.76e-15 Corneal astigmatism; LIHC cis rs72772090 0.614 rs10447215 chr5:96056373 G/C cg17330273 chr5:96107758 CAST;ERAP1 -0.63 -6.98 -0.35 1.5e-11 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs1814175 0.645 rs28538913 chr11:50040718 C/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs13394619 0.655 rs7578132 chr2:11718858 C/T cg07314298 chr2:11723111 GREB1 -0.42 -7.93 -0.39 3.07e-14 Endometriosis; LIHC trans rs4604234 0.803 rs73463519 chr6:80976579 C/T cg08069338 chr6:160207898 SNORA29;TCP1 0.63 6.09 0.31 3.01e-9 Cancer; LIHC cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg03806693 chr22:41940476 POLR3H 1.09 13.05 0.58 7.36e-32 Vitiligo; LIHC cis rs3793683 0.928 rs10781585 chr10:134553369 C/A cg18305652 chr10:134549665 INPP5A -0.37 -6.16 -0.32 2.02e-9 Migraine; LIHC cis rs2637266 0.934 rs2395408 chr10:78380929 G/A cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC cis rs8067354 0.574 rs1291947 chr17:57996336 G/T cg02344993 chr17:57696989 CLTC 0.66 10.41 0.49 3.03e-22 Hemoglobin concentration; LIHC cis rs4700695 0.841 rs251614 chr5:65228251 C/G cg21114390 chr5:65439923 SFRS12 -0.49 -6.56 -0.33 2.01e-10 Facial morphology (factor 19); LIHC cis rs68170813 0.559 rs4730232 chr7:106942382 G/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs57221529 0.664 rs72704802 chr5:554211 C/T cg09021430 chr5:549028 NA -0.45 -8.58 -0.42 3.36e-16 Lung disease severity in cystic fibrosis; LIHC cis rs9911578 0.935 rs420878 chr17:56709077 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.77 0.69 1.65e-50 Intelligence (multi-trait analysis); LIHC cis rs3015497 0.753 rs12881776 chr14:51136330 T/G cg09863266 chr14:51125203 SAV1 -0.41 -6.58 -0.34 1.76e-10 Mean platelet volume; LIHC cis rs35110281 0.511 rs2298562 chr21:45085236 A/G cg01579765 chr21:45077557 HSF2BP -0.31 -5.72 -0.3 2.3e-8 Mean corpuscular volume; LIHC cis rs11864453 0.612 rs11862813 chr16:72132356 C/T cg16558253 chr16:72132732 DHX38 -0.44 -7.29 -0.37 2.22e-12 Fibrinogen levels; LIHC cis rs6582630 0.537 rs35336822 chr12:38346251 T/C cg26384229 chr12:38710491 ALG10B 0.56 7.71 0.38 1.35e-13 Drug-induced liver injury (flucloxacillin); LIHC cis rs4819052 0.851 rs9974628 chr21:46672647 C/T cg11663144 chr21:46675770 NA -0.32 -5.92 -0.3 7.84e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12915845 0.545 rs12907930 chr15:89083314 A/G cg05013243 chr15:89149849 MIR1179 0.36 6.49 0.33 2.99e-10 Menarche (age at onset); LIHC cis rs636291 0.500 rs655271 chr1:10536635 G/A cg17425144 chr1:10567563 PEX14 0.52 10.24 0.48 1.26e-21 Prostate cancer; LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.57 -8.28 -0.41 2.81e-15 Lymphocyte counts; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05439608 chr7:156761192 NOM1 0.44 6.9 0.35 2.58e-11 Longevity; LIHC cis rs311392 0.554 rs2666883 chr8:55100897 A/G cg20636351 chr8:55087400 NA -0.35 -7.24 -0.36 2.94e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs10612751 1 rs10612751 chr13:107646032 CTG/C cg04314986 chr13:107569408 NA 0.35 6.49 0.33 3.03e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.26 0.52 3.09e-25 Colorectal cancer; LIHC cis rs9807989 0.507 rs2293224 chr2:103035779 T/C cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma; LIHC cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg11890956 chr21:40555474 PSMG1 0.93 12.58 0.56 4.54e-30 Cognitive function; LIHC cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.45 8.14 0.4 7.37e-15 Prudent dietary pattern; LIHC cis rs3888647 0.622 rs4758618 chr11:2995186 A/T cg08508325 chr11:3079039 CARS -0.27 -5.9 -0.3 8.82e-9 Type 2 diabetes; LIHC cis rs1568889 1.000 rs11604085 chr11:28141002 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.91 0.35 2.36e-11 Bipolar disorder; LIHC cis rs2412488 0.893 rs12507563 chr4:54363194 A/G cg22241045 chr4:54363911 LNX1 0.46 7.64 0.38 2.15e-13 DNA methylation (variation); LIHC cis rs778371 0.697 rs4973564 chr2:233718440 A/G cg08000102 chr2:233561755 GIGYF2 -0.86 -14.4 -0.61 4.41e-37 Schizophrenia; LIHC cis rs7845219 0.506 rs12548999 chr8:95929843 C/T cg16049864 chr8:95962084 TP53INP1 -0.44 -6.51 -0.33 2.68e-10 Type 2 diabetes; LIHC cis rs2836974 0.644 rs7281853 chr21:40693490 A/G cg06238570 chr21:40685208 BRWD1 -0.52 -8.43 -0.41 9.55e-16 Cognitive function; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg11809123 chr19:1584870 MBD3 0.45 6.7 0.34 8.77e-11 Alopecia areata; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16627807 chr19:40596541 ZNF780A 0.47 6.76 0.34 6.02e-11 Pancreatic cancer; LIHC trans rs4942242 0.663 rs17460812 chr13:44215504 A/G cg19169023 chr15:41853346 TYRO3 -0.51 -7.4 -0.37 1.04e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs918629 0.567 rs3777196 chr5:95238160 A/C cg10483112 chr5:95245456 ELL2 -0.37 -6.82 -0.35 4.03e-11 IgG glycosylation; LIHC cis rs12594515 1.000 rs6493169 chr15:45986994 A/G cg19682013 chr15:45996608 NA -0.4 -7.09 -0.36 7.6e-12 Waist circumference;Weight; LIHC cis rs12579753 1.000 rs12811607 chr12:82233619 T/G cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs11792861 1.000 rs11792861 chr9:111809295 A/C cg05043794 chr9:111880884 C9orf5 -0.27 -6.42 -0.33 4.58e-10 Menarche (age at onset); LIHC cis rs847851 0.617 rs11970238 chr6:34945143 T/C cg13137465 chr6:34857473 ANKS1A 0.67 7.45 0.37 7.92e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs6942756 0.806 rs2718096 chr7:128951000 A/G cg02491457 chr7:128862824 NA 0.57 8.74 0.43 1.07e-16 White matter hyperintensity burden; LIHC trans rs668210 0.793 rs1786172 chr11:65770658 A/G cg17712092 chr4:129076599 LARP1B 0.58 6.24 0.32 1.29e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg19318889 chr4:1322082 MAEA -0.48 -7.92 -0.39 3.27e-14 Obesity-related traits; LIHC cis rs4148883 0.675 rs116265877 chr4:100096896 G/A cg12011299 chr4:100065546 ADH4 0.37 7.28 0.37 2.34e-12 Alcohol dependence; LIHC cis rs2834256 0.517 rs9976290 chr21:34928329 G/A cg14850771 chr21:34775459 IFNGR2 0.45 7.18 0.36 4.47e-12 Red cell distribution width; LIHC cis rs1008375 1.000 rs2058339 chr4:17678456 C/T cg02297831 chr4:17616191 MED28 0.43 6.94 0.35 2.01e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2839186 1.000 rs2839181 chr21:47685939 A/G cg13126279 chr21:47581558 C21orf56 -0.45 -7.13 -0.36 5.96e-12 Testicular germ cell tumor; LIHC cis rs5770917 1.000 rs8137478 chr22:51017296 G/C cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.51 -6.92 -0.35 2.19e-11 Narcolepsy; LIHC cis rs6762 0.748 rs7929032 chr11:839078 G/A cg15787769 chr11:842744 TSPAN4;POLR2L -0.62 -7.47 -0.37 6.92e-13 Mean platelet volume; LIHC cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.63 0.53 1.49e-26 Alzheimer's disease; LIHC cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg19318889 chr4:1322082 MAEA 0.4 6.63 0.34 1.32e-10 Obesity-related traits; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg10150615 chr22:24372951 LOC391322 0.49 6.84 0.35 3.63e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs2262909 0.962 rs56369285 chr19:22267185 T/C cg05197062 chr11:11642011 GALNTL4 0.43 6.14 0.32 2.34e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs3091242 0.933 rs61775174 chr1:25787313 G/A cg02931644 chr1:25747376 RHCE -0.33 -6.94 -0.35 1.97e-11 Erythrocyte sedimentation rate; LIHC cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs8081395 0.651 rs1292067 chr17:57930646 A/C cg13753209 chr17:57696993 CLTC -0.5 -8.08 -0.4 1.1e-14 White blood cell count; LIHC cis rs8017423 0.935 rs3783838 chr14:90733012 A/G cg04374321 chr14:90722782 PSMC1 -0.73 -13.98 -0.6 1.85e-35 Mortality in heart failure; LIHC cis rs1057239 0.739 rs1014554 chr1:175133626 A/G cg00321850 chr1:175162397 KIAA0040 0.45 7.34 0.37 1.57e-12 Diastolic blood pressure; LIHC trans rs17685 0.753 rs11972240 chr7:75694079 A/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.04 0.72 1.22e-55 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35110281 0.807 rs1598206 chr21:45058776 A/G cg04455712 chr21:45112962 RRP1B 0.47 8.03 0.4 1.64e-14 Mean corpuscular volume; LIHC cis rs7551222 0.752 rs885012 chr1:204544001 C/A cg20240347 chr1:204465584 NA -0.35 -7.19 -0.36 4.04e-12 Schizophrenia; LIHC cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg08645402 chr16:4508243 NA 0.46 9.09 0.44 8.17e-18 Schizophrenia; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg11235426 chr6:292522 DUSP22 -0.55 -7.75 -0.39 1.09e-13 Menopause (age at onset); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg12655621 chr3:133380788 TOPBP1 -0.41 -6.99 -0.35 1.45e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs7605378 0.528 rs281767 chr2:200823281 C/A cg23649088 chr2:200775458 C2orf69 0.57 8.41 0.41 1.1e-15 Osteoporosis; LIHC cis rs921968 0.541 rs485975 chr2:219374250 C/T cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC trans rs61931739 0.500 rs2389269 chr12:34034179 C/T cg26384229 chr12:38710491 ALG10B 0.52 7.21 0.36 3.62e-12 Morning vs. evening chronotype; LIHC cis rs12477438 0.734 rs4851184 chr2:99666434 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.53 -0.49 1.24e-22 Chronic sinus infection; LIHC cis rs9503598 0.636 rs6596974 chr6:3465833 C/T cg00476032 chr6:3446245 SLC22A23 0.4 7.75 0.39 1.08e-13 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17175324 chr11:64009423 FKBP2 -0.52 -6.18 -0.32 1.83e-9 Systolic blood pressure; LIHC cis rs12594515 1.000 rs8027000 chr15:45987795 T/C cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.69e-10 Waist circumference;Weight; LIHC cis rs2304069 0.779 rs245050 chr5:149346960 C/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.7 -9.24 -0.45 2.75e-18 HIV-1 control; LIHC cis rs6121246 0.738 rs2376996 chr20:30316667 T/A cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC cis rs6912958 1.000 rs9450701 chr6:88173167 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.09 -0.36 7.51e-12 Monocyte percentage of white cells; LIHC cis rs780096 0.565 rs10169261 chr2:27727314 C/T cg27432699 chr2:27873401 GPN1 -0.56 -8.03 -0.4 1.59e-14 Total body bone mineral density; LIHC cis rs17818399 0.547 rs13020299 chr2:46758717 A/G cg02822958 chr2:46747628 ATP6V1E2 0.43 6.32 0.32 8.19e-10 Height; LIHC cis rs4629710 0.592 rs66533103 chr6:131531016 C/T cg12606694 chr6:131520996 AKAP7 0.58 6.76 0.34 5.8e-11 Multiple myeloma (IgH translocation); LIHC cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg24642844 chr7:1081250 C7orf50 -0.7 -7.03 -0.36 1.16e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7843479 1.000 rs17615788 chr8:21814739 C/T cg17168535 chr8:21777572 XPO7 0.42 6.48 0.33 3.15e-10 Mean corpuscular volume; LIHC cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg27297192 chr10:134578999 INPP5A 0.53 7.55 0.38 4e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6570726 0.791 rs6570695 chr6:145911286 C/A cg23711669 chr6:146136114 FBXO30 0.7 11.65 0.53 1.22e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs3858145 0.588 rs78041174 chr10:70038771 G/A cg04882175 chr6:131122610 NA -0.48 -6.07 -0.31 3.33e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs11924390 0.749 rs822364 chr3:186452716 A/G cg12454167 chr3:186435060 KNG1 0.32 7.68 0.38 1.73e-13 Adiponectin levels; LIHC cis rs116095464 0.558 rs28558836 chr5:285748 C/G cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs208520 0.955 rs12202599 chr6:67001573 A/G cg07460842 chr6:66804631 NA 0.66 7.07 0.36 8.62e-12 Exhaled nitric oxide output; LIHC cis rs3749237 0.595 rs11130192 chr3:49467206 C/G cg03060546 chr3:49711283 APEH 0.63 10.41 0.49 3.16e-22 Resting heart rate; LIHC cis rs9649465 0.934 rs7799354 chr7:123269819 A/G cg03229431 chr7:123269106 ASB15 -0.4 -8.94 -0.44 2.45e-17 Migraine; LIHC cis rs644148 0.867 rs2571060 chr19:44971647 C/G cg15540054 chr19:45004280 ZNF180 -0.77 -11.42 -0.53 8.63e-26 Personality dimensions; LIHC cis rs7845219 0.544 rs7015841 chr8:95920193 A/C cg16049864 chr8:95962084 TP53INP1 -0.44 -6.6 -0.34 1.58e-10 Type 2 diabetes; LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg02290350 chr8:58132656 NA 0.52 11.18 0.52 6.19e-25 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg03396347 chr1:1875803 NA -0.45 -8.09 -0.4 1.08e-14 Body mass index; LIHC cis rs1707322 0.721 rs11211151 chr1:46112752 T/C cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6759839 0.716 rs6531114 chr2:16617781 T/C cg09580478 chr2:16689509 NA 0.64 6.25 0.32 1.21e-9 Mean platelet volume; LIHC cis rs12220238 1.000 rs7909664 chr10:75869754 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.95 0.35 1.9e-11 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs2243480 1.000 rs462853 chr7:65558167 G/C cg10756647 chr7:56101905 PSPH 1.06 13.26 0.58 1.11e-32 Diabetic kidney disease; LIHC cis rs9814567 1.000 rs13071551 chr3:134310867 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.22 0.32 1.49e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11098699 1.000 rs4833884 chr4:124175208 G/A cg09941581 chr4:124220074 SPATA5 0.33 6.27 0.32 1.09e-9 Mosquito bite size; LIHC trans rs6600671 1.000 rs4844381 chr1:121184898 C/T cg09829573 chr1:144692074 NBPF9 -0.43 -7.87 -0.39 4.56e-14 Hip geometry; LIHC cis rs9467773 1.000 rs9467797 chr6:26568473 A/T cg11502198 chr6:26597334 ABT1 0.46 6.71 0.34 8.01e-11 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.931 rs35743647 chr1:46407252 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.89 0.3 9.33e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg01238044 chr22:24384105 GSTT1 -0.44 -5.9 -0.3 8.54e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg18404041 chr3:52824283 ITIH1 -0.58 -9.71 -0.46 7.5599999999999994e-20 Electroencephalogram traits; LIHC cis rs12220238 1.000 rs7909915 chr10:75960942 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.22 0.32 1.47e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs11718455 0.767 rs11708363 chr3:43966585 G/A cg08738300 chr3:44038990 NA 0.53 8.94 0.44 2.48e-17 Coronary artery disease; LIHC trans rs17685 0.672 rs55807301 chr7:75807401 C/A cg19862616 chr7:65841803 NCRNA00174 0.91 18.74 0.71 2.14e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11628318 0.614 rs62007925 chr14:103128288 G/A cg01864069 chr14:103024347 NA 0.45 6.98 0.35 1.51e-11 Platelet count; LIHC cis rs8077889 0.703 rs72836567 chr17:41945776 G/A cg26893861 chr17:41843967 DUSP3 0.84 7.5 0.38 5.72e-13 Triglycerides; LIHC cis rs4713118 0.586 rs6905522 chr6:28086479 A/C cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Parkinson's disease; LIHC cis rs2710642 0.564 rs6545962 chr2:62821318 G/A cg17519650 chr2:63277830 OTX1 0.41 6.4 0.33 5.02e-10 LDL cholesterol levels;LDL cholesterol; LIHC cis rs7208859 0.623 rs609063 chr17:28951513 A/G cg13385521 chr17:29058706 SUZ12P 0.68 6.61 0.34 1.5e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1008375 0.966 rs7658240 chr4:17588950 A/G cg02297831 chr4:17616191 MED28 -0.42 -5.77 -0.3 1.73e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs68170813 0.559 rs6965001 chr7:106933196 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg07424592 chr7:64974309 NA 0.75 8.79 0.43 7.66e-17 Diabetic kidney disease; LIHC cis rs7729447 0.776 rs4867472 chr5:32693566 C/T cg16267343 chr5:32710456 NPR3 0.47 5.78 0.3 1.71e-8 Blood pressure; LIHC cis rs8017423 0.967 rs12589808 chr14:90719236 C/T cg04374321 chr14:90722782 PSMC1 -0.75 -14.39 -0.61 4.78e-37 Mortality in heart failure; LIHC cis rs35146811 0.844 rs13223792 chr7:99675659 T/G cg22906224 chr7:99728672 NA 0.42 5.94 0.31 6.95e-9 Coronary artery disease; LIHC cis rs6545883 0.931 rs12713438 chr2:61725501 G/A cg15711740 chr2:61764176 XPO1 -0.41 -5.85 -0.3 1.15e-8 Tuberculosis; LIHC cis rs8027181 0.839 rs10459647 chr15:73035241 T/C cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 8.01 0.4 1.78e-14 Triglyceride levels; LIHC cis rs722599 0.748 rs55707505 chr14:75362552 T/C cg11812906 chr14:75593930 NEK9 -0.47 -7.45 -0.37 7.94e-13 IgG glycosylation; LIHC cis rs77216612 0.835 rs10845621 chr12:12887977 C/T cg09462578 chr12:12878428 APOLD1 -0.92 -15.47 -0.64 2.63e-41 Lymphocyte counts; LIHC cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg02290350 chr8:58132656 NA 0.41 8.43 0.41 9.79e-16 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.924 rs7938360 chr11:111539875 A/G cg09085632 chr11:111637200 PPP2R1B -1.04 -13.32 -0.58 6.78e-33 Primary sclerosing cholangitis; LIHC cis rs12926788 0.542 rs11862971 chr16:24767574 C/A cg00152838 chr16:24741724 TNRC6A -0.51 -6.3 -0.32 9.08e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs79600951 1.000 rs76233589 chr16:56769902 A/G cg03486475 chr5:140796240 PCDHGA4;PCDHGA9;PCDHGA1;PCDHGB1;PCDHGB6;PCDHGB3;PCDHGB7;PCDHGA6;PCDHGA8;PCDHGA10;PCDHGA5;PCDHGB4;PCDHGA3;PCDHGA2;PCDHGB2;PCDHGA7;PCDHGB5 0.52 6.05 0.31 3.72e-9 HDL cholesterol; LIHC cis rs2084898 0.891 rs477361 chr11:120000873 T/G cg13907859 chr11:120009124 TRIM29 -0.53 -6.57 -0.33 1.86e-10 Stroke (pediatric); LIHC cis rs5769765 0.862 rs9616386 chr22:50313179 G/A cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs1797081 1.000 rs812426 chr10:16857133 C/G cg23933602 chr10:16859644 RSU1 1.05 22.07 0.77 9.69e-68 Platelet distribution width; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg00800038 chr16:89945340 TCF25 -0.61 -9.98 -0.48 9.06e-21 Skin colour saturation; LIHC cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg23758822 chr17:41437982 NA 0.94 18.0 0.7 1.99e-51 Menopause (age at onset); LIHC cis rs311392 0.867 rs364484 chr8:55093492 G/T cg20636351 chr8:55087400 NA -0.38 -7.73 -0.39 1.2e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs9596863 0.898 rs34107297 chr13:54374962 A/T ch.13.53330881F chr13:54432880 NA 0.43 5.8 0.3 1.53e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs4903214 0.895 rs1005740 chr14:74695332 A/G cg11132536 chr14:74711944 VSX2 -0.26 -6.18 -0.32 1.78e-9 Inflammatory bowel disease; LIHC cis rs6545883 0.929 rs7561229 chr2:61737990 A/T cg15711740 chr2:61764176 XPO1 -0.42 -6.02 -0.31 4.61e-9 Tuberculosis; LIHC cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg01448562 chr3:133502909 NA 0.42 6.53 0.33 2.32e-10 Iron status biomarkers; LIHC cis rs13108904 0.901 rs4974594 chr4:1300480 C/T cg19318889 chr4:1322082 MAEA -0.46 -7.71 -0.38 1.34e-13 Obesity-related traits; LIHC cis rs7465272 1.000 rs7465272 chr8:143691838 A/T cg10104451 chr8:143696006 ARC -0.56 -7.66 -0.38 1.91e-13 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.597 rs11771318 chr7:66062480 G/T cg11764359 chr7:65958608 NA -0.69 -8.92 -0.43 2.91e-17 Aortic root size; LIHC cis rs7208859 0.673 rs11658344 chr17:29207745 G/T cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6489882 0.867 rs916972 chr12:113366049 G/T cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs611744 0.967 rs2597654 chr8:109221090 A/G cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.19e-10 Dupuytren's disease; LIHC cis rs1461503 1.000 rs1461499 chr11:122843987 C/A cg25161029 chr11:122845972 NA 0.33 5.81 0.3 1.41e-8 Menarche (age at onset); LIHC cis rs7715806 0.500 rs4704233 chr5:75000792 G/A cg00601450 chr5:74908170 NA 0.52 6.43 0.33 4.2e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs782590 0.748 rs782634 chr2:55897700 T/C cg03859395 chr2:55845619 SMEK2 0.74 12.29 0.55 5.25e-29 Metabolic syndrome; LIHC cis rs17826219 0.706 rs9905827 chr17:29192168 C/A cg13385521 chr17:29058706 SUZ12P 0.83 8.03 0.4 1.62e-14 Body mass index; LIHC cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.81 7.91 0.39 3.58e-14 Platelet count; LIHC cis rs1728785 1.000 rs1728773 chr16:68563644 A/C cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs243505 0.660 rs3779037 chr7:148539323 T/C cg09806900 chr7:148480153 CUL1 0.43 6.1 0.31 2.82e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6952808 0.609 rs12699453 chr7:1953056 C/T cg20295408 chr7:1910781 MAD1L1 -0.52 -7.6 -0.38 2.86e-13 Bipolar disorder and schizophrenia; LIHC cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.56 8.82 0.43 5.94e-17 Schizophrenia; LIHC cis rs4555082 0.834 rs1473672 chr14:105721981 G/T cg13114125 chr14:105738426 BRF1 -0.72 -9.35 -0.45 1.21e-18 Mean platelet volume;Platelet distribution width; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg23964739 chr19:45909864 CD3EAP;PPP1R13L -0.44 -6.16 -0.32 2.09e-9 Triglycerides; LIHC cis rs7089973 0.604 rs765173 chr10:116601675 C/T cg03647239 chr10:116582469 FAM160B1 0.47 6.83 0.35 3.85e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs35883536 1.000 rs34441740 chr1:101137046 C/G cg14515779 chr1:101123966 NA -0.7 -14.03 -0.6 1.21e-35 Monocyte count; LIHC cis rs4891159 0.548 rs609487 chr18:74134382 C/G cg24786174 chr18:74118243 ZNF516 -0.79 -16.62 -0.67 6.65e-46 Longevity; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.91 -0.3 8.13e-9 Total body bone mineral density; LIHC cis rs2576037 0.583 rs578451 chr18:44404525 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 9.8 0.47 3.67e-20 Personality dimensions; LIHC cis rs7917772 0.503 rs11191326 chr10:104302959 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.05 0.58 7.17e-32 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.832 rs61056817 chr3:10027641 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.6 0.46 1.77e-19 Alzheimer's disease; LIHC cis rs73001065 0.591 rs57962361 chr19:19425025 C/T cg03709012 chr19:19516395 GATAD2A 0.81 8.66 0.42 1.85e-16 LDL cholesterol; LIHC cis rs992157 0.560 rs4674274 chr2:219089131 A/T cg00012203 chr2:219082015 ARPC2 -0.88 -15.33 -0.64 9.23e-41 Colorectal cancer; LIHC cis rs9325144 0.647 rs7316392 chr12:39064381 T/G cg26384229 chr12:38710491 ALG10B -0.43 -6.13 -0.31 2.44e-9 Morning vs. evening chronotype; LIHC cis rs10411936 1.000 rs11878602 chr19:16555153 A/C cg10248733 chr19:16607483 C19orf44;CALR3 -0.42 -5.72 -0.3 2.28e-8 White blood cell count;Multiple sclerosis; LIHC cis rs1451375 1.000 rs1451375 chr7:50622712 A/C cg14593290 chr7:50529359 DDC -0.4 -6.59 -0.34 1.66e-10 Malaria; LIHC cis rs12286929 0.637 rs34138164 chr11:115050127 A/G cg04055981 chr11:115044050 NA 0.53 8.25 0.41 3.56e-15 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg16434002 chr17:42200994 HDAC5 -0.53 -7.71 -0.38 1.4e-13 Total body bone mineral density; LIHC cis rs7224314 1.000 rs62084079 chr17:65386917 C/T cg01507342 chr17:65387096 PITPNC1 -0.48 -6.01 -0.31 4.63e-9 Diisocyanate-induced asthma; LIHC cis rs12477438 0.765 rs56167745 chr2:99600478 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -8.6 -0.42 2.93e-16 Chronic sinus infection; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg11494091 chr17:61959527 GH2 0.43 7.91 0.39 3.64e-14 Prudent dietary pattern; LIHC cis rs477895 1.000 rs66968227 chr11:64070930 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 7.98 0.4 2.22e-14 Mean platelet volume; LIHC cis rs9486719 1.000 rs12201449 chr6:96959382 C/T cg06623918 chr6:96969491 KIAA0776 -0.7 -7.03 -0.36 1.13e-11 Migraine;Coronary artery disease; LIHC cis rs9612 1.000 rs346534 chr19:44250831 A/G cg08581076 chr19:44259116 C19orf61 0.67 8.64 0.42 2.13e-16 Exhaled nitric oxide output; LIHC cis rs6120849 0.754 rs6120819 chr20:33653038 T/C cg24642439 chr20:33292090 TP53INP2 0.65 6.99 0.35 1.46e-11 Protein C levels; LIHC cis rs933688 1.000 rs12656350 chr5:90751343 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.26 0.72 1.73e-56 Smoking behavior; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg11494091 chr17:61959527 GH2 0.44 8.17 0.4 6.08e-15 Prudent dietary pattern; LIHC cis rs80282103 0.867 rs74117668 chr10:1076620 C/T cg20335179 chr10:1068567 C10orf110;IDI2 -0.61 -6.75 -0.34 6.5e-11 Glomerular filtration rate (creatinine); LIHC cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2204008 0.592 rs2320501 chr12:38145285 T/G cg26384229 chr12:38710491 ALG10B 0.83 9.94 0.47 1.27e-20 Bladder cancer; LIHC cis rs896854 0.516 rs12679044 chr8:95891356 C/A cg16049864 chr8:95962084 TP53INP1 -0.57 -10.08 -0.48 4.17e-21 Type 2 diabetes; LIHC cis rs11229555 0.645 rs4367960 chr11:58194961 C/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2228479 0.618 rs17233623 chr16:89811209 C/T cg19635926 chr16:89946313 TCF25 0.48 6.24 0.32 1.32e-9 Skin colour saturation; LIHC trans rs7618501 0.966 rs7372966 chr3:49788969 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.81 -0.63 1.14e-38 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.526 rs9376928 chr6:145724403 T/G cg23711669 chr6:146136114 FBXO30 -0.35 -5.72 -0.3 2.3e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs644799 1.000 rs580255 chr11:95577929 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.49 0.67 2.29e-45 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg05555928 chr11:63887634 MACROD1 0.53 7.07 0.36 8.67e-12 Mean platelet volume; LIHC cis rs2404602 0.583 rs2139190 chr15:76555539 G/C cg23625390 chr15:77176239 SCAPER 0.34 5.99 0.31 5.3300000000000004e-09 Blood metabolite levels; LIHC trans rs1499614 1.000 rs1267818 chr7:66107024 C/T cg07424592 chr7:64974309 NA 0.78 8.84 0.43 4.99e-17 Gout; LIHC cis rs7264396 0.563 rs2425094 chr20:34306974 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC cis rs8053891 0.507 rs10852510 chr16:72026041 G/A cg01557791 chr16:72042693 DHODH -0.4 -6.29 -0.32 9.85e-10 Coronary artery disease; LIHC cis rs10736390 1.000 rs11206402 chr1:55104317 G/C cg01517571 chr1:55089959 ACOT11;FAM151A -0.46 -7.99 -0.4 2.06e-14 Survival in pancreatic cancer; LIHC cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg12463550 chr7:65579703 CRCP -0.73 -7.64 -0.38 2.26e-13 Diabetic kidney disease; LIHC cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg19774624 chr17:42201019 HDAC5 -0.82 -12.74 -0.57 1.07e-30 Total body bone mineral density; LIHC cis rs2637266 0.935 rs12772269 chr10:78394292 C/A cg18941641 chr10:78392320 NA 0.29 6.4 0.33 5.23e-10 Pulmonary function; LIHC cis rs3096299 0.874 rs3102342 chr16:89451575 T/C cg00750074 chr16:89608354 SPG7 -0.39 -5.97 -0.31 6.09e-9 Multiple myeloma (IgH translocation); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06995624 chr17:73043174 ATP5H;KCTD2 0.46 6.59 0.34 1.71e-10 Lung function (FEV1/FVC); LIHC cis rs920590 0.758 rs1826420 chr8:19664878 G/T cg01411142 chr8:19674711 INTS10 0.5 7.72 0.39 1.28e-13 Acute lymphoblastic leukemia (childhood); LIHC trans rs11098499 0.863 rs6858777 chr4:120475966 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.36 0.45 1.08e-18 Corneal astigmatism; LIHC cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg09904177 chr6:26538194 HMGN4 0.53 10.24 0.48 1.25e-21 Intelligence (multi-trait analysis); LIHC cis rs16858210 0.874 rs6792309 chr3:183607661 C/T cg25686905 chr3:183603175 PARL -0.48 -9.07 -0.44 9.25e-18 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05000123 chr14:20937394 PNP 0.43 6.14 0.32 2.23e-9 Pancreatic cancer; LIHC cis rs11675119 0.501 rs9751941 chr2:3494262 C/T cg15506890 chr2:3487001 NA -0.44 -6.6 -0.34 1.58e-10 Neurofibrillary tangles; LIHC cis rs116095464 0.558 rs62347677 chr5:227453 A/G cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC trans rs800082 0.698 rs800070 chr3:144346614 A/T cg24215973 chr2:240111563 HDAC4 -0.62 -9.58 -0.46 2.03e-19 Smoking behavior; LIHC cis rs250677 0.652 rs250680 chr5:148436024 T/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.52 -0.38 4.9e-13 Breast cancer; LIHC cis rs7107174 0.901 rs1046780 chr11:77926769 A/G cg02023728 chr11:77925099 USP35 0.49 9.51 0.46 3.63e-19 Testicular germ cell tumor; LIHC cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg21448741 chr8:58168803 NA 0.37 6.0 0.31 5.11e-9 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.959 rs11904009 chr2:172627343 T/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.7 -0.69 3.13e-50 Schizophrenia; LIHC cis rs4906332 1.000 rs7155822 chr14:103922390 A/G cg26031613 chr14:104095156 KLC1 -0.42 -5.84 -0.3 1.22e-8 Coronary artery disease; LIHC cis rs897984 0.568 rs8050107 chr16:30893451 C/T cg02466173 chr16:30829666 NA 0.41 6.1 0.31 2.91e-9 Dementia with Lewy bodies; LIHC cis rs7523273 1.000 rs12184327 chr1:207978780 A/G cg22525895 chr1:207977042 MIR29B2 -0.69 -11.09 -0.51 1.24e-24 Schizophrenia; LIHC cis rs9326778 0.520 rs6893387 chr5:108848237 G/A cg17395555 chr5:108820864 NA -0.34 -5.76 -0.3 1.92e-8 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 11.85 0.54 2.17e-27 Height; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.81 0.63 1.12e-38 Prudent dietary pattern; LIHC cis rs3806843 0.933 rs2240696 chr5:140168070 A/G cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1008375 1.000 rs3815414 chr4:17606659 A/G cg16339924 chr4:17578868 LAP3 -0.44 -6.02 -0.31 4.41e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs17685 0.712 rs1637049 chr7:75729975 C/G cg19862616 chr7:65841803 NCRNA00174 0.92 18.56 0.71 1.12e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17401966 0.518 rs10864453 chr1:10407169 T/G cg19773385 chr1:10388646 KIF1B -0.32 -5.75 -0.3 2e-8 Hepatocellular carcinoma; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20225246 chr19:2200020 DOT1L -0.42 -6.16 -0.32 2.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6598955 0.670 rs4659366 chr1:26542572 G/A cg00852783 chr1:26633632 UBXN11 0.48 8.12 0.4 8.36e-15 Obesity-related traits; LIHC cis rs35110281 0.627 rs11701746 chr21:44975137 C/T cg21573476 chr21:45109991 RRP1B -0.5 -9.2 -0.45 3.53e-18 Mean corpuscular volume; LIHC cis rs4665809 1.000 rs4665821 chr2:26309949 A/C cg04944784 chr2:26401820 FAM59B -0.65 -8.29 -0.41 2.58e-15 Gut microbiome composition (summer); LIHC cis rs7107174 1.000 rs55825352 chr11:78034424 C/T cg02023728 chr11:77925099 USP35 0.5 9.63 0.46 1.37e-19 Testicular germ cell tumor; LIHC cis rs11122272 0.701 rs1009227 chr1:231480507 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.14 0.44 5.69e-18 Hemoglobin concentration; LIHC trans rs208520 0.690 rs851458 chr6:66813279 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.85 -9.22 -0.45 3.03e-18 Exhaled nitric oxide output; LIHC cis rs7075426 0.905 rs1896514 chr10:88175881 G/A cg07322936 chr10:88137208 NA 0.5 6.78 0.34 5.43e-11 Migraine without aura; LIHC cis rs7503807 0.967 rs7215486 chr17:78612034 C/T cg09596252 chr17:78655493 RPTOR 0.38 6.89 0.35 2.62e-11 Obesity; LIHC cis rs13191362 1.000 rs73016459 chr6:163066323 C/A cg14584255 chr6:163149320 PACRG;PARK2 0.64 5.74 0.3 2.11e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs140364877 1 rs140364877 chr7:1885178 C/T cg02951883 chr7:2050386 MAD1L1 -0.51 -7.56 -0.38 3.83e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs8114671 0.562 rs6119545 chr20:33522869 T/C cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.01e-19 Height; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.83 -0.3 1.25e-8 Total body bone mineral density; LIHC cis rs3845702 0.736 rs6727890 chr2:180832675 T/C cg01881094 chr2:180872142 CWC22 -1.14 -10.24 -0.48 1.26e-21 Schizophrenia; LIHC cis rs6088580 0.634 rs6119497 chr20:33012529 T/A cg08999081 chr20:33150536 PIGU 0.67 13.28 0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs10504073 0.647 rs10435574 chr8:49996028 G/A cg00325661 chr8:49890786 NA 0.33 7.65 0.38 2.1e-13 Blood metabolite ratios; LIHC cis rs6066825 0.554 rs4809711 chr20:47235811 T/C cg18078177 chr20:47281410 PREX1 0.48 8.01 0.4 1.84e-14 Colorectal cancer; LIHC cis rs921968 0.643 rs545779 chr2:219336108 A/G cg02985541 chr2:219472218 PLCD4 0.46 8.79 0.43 7.39e-17 Mean corpuscular hemoglobin concentration; LIHC cis rs2070488 0.965 rs2051216 chr3:38562288 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.68 -0.62 3.69e-38 Electrocardiographic conduction measures; LIHC cis rs7072216 0.763 rs45523432 chr10:100167436 T/C cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC cis rs59698941 0.943 rs739863 chr5:132232315 C/T cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs11146838 1 rs11146838 chr10:39149977 A/T cg03665457 chr10:38645376 HSD17B7P2 -0.45 -6.37 -0.33 6.1e-10 Breast cancer; LIHC cis rs10792665 0.512 rs7112902 chr11:82589761 G/T cg24227371 chr11:82718527 RAB30 -0.28 -6.58 -0.34 1.78e-10 Obesity-related traits; LIHC cis rs933688 1.000 rs2052553 chr5:90729906 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 20.88 0.75 5.2e-63 Smoking behavior; LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg20887711 chr4:1340912 KIAA1530 0.8 12.43 0.56 1.56e-29 Longevity; LIHC cis rs244293 0.868 rs171510 chr17:53211527 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22879676 chr17:81009871 B3GNTL1 0.51 7.43 0.37 8.89e-13 Lung function (FEV1/FVC); LIHC cis rs908922 0.676 rs486283 chr1:152525957 A/G cg20991723 chr1:152506922 NA 0.52 8.81 0.43 6.54e-17 Hair morphology; LIHC cis rs892961 0.932 rs3987885 chr17:75414990 A/G cg01320579 chr17:75405842 SEPT9 0.52 7.33 0.37 1.64e-12 Airflow obstruction; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs2273156 1.000 rs12050447 chr14:35461965 A/G cg16230307 chr14:35515116 FAM177A1 -0.41 -6.04 -0.31 3.96e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs614226 0.938 rs7972244 chr12:120994872 A/G cg27489772 chr12:121021490 NA 0.52 5.72 0.3 2.33e-8 Type 1 diabetes nephropathy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04139300 chr20:40247070 CHD6 0.45 6.7 0.34 8.59e-11 Cognitive function; LIHC cis rs9473924 0.505 rs7756058 chr6:50904438 G/A cg14470998 chr6:50812995 TFAP2B 0.93 10.85 0.51 9.2e-24 Body mass index; LIHC cis rs28595532 0.702 rs72670256 chr4:119391043 G/A cg21605333 chr4:119757512 SEC24D 1.03 7.8 0.39 7.67e-14 Cannabis dependence symptom count; LIHC cis rs116095464 0.558 rs7356696 chr5:284251 A/G cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs2029362 0.611 rs10835215 chr11:27739949 C/T cg18117895 chr11:27722066 BDNF -0.4 -5.94 -0.31 6.85e-9 Total body bone mineral density; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg22018329 chr19:3116716 GNA11 0.39 6.16 0.32 2e-9 Oropharynx cancer; LIHC cis rs6963495 0.818 rs73190156 chr7:105153567 C/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2637030 0.501 rs375956 chr5:52883715 C/G cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.24e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs3008870 1.000 rs2755245 chr1:67487964 C/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 15.7 0.65 3.28e-42 Lymphocyte percentage of white cells; LIHC cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg26818010 chr10:134567672 INPP5A -0.74 -8.78 -0.43 8.25e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11809123 chr19:1584870 MBD3 0.44 6.38 0.33 5.75e-10 Longevity; LIHC trans rs11098499 0.691 rs9995716 chr4:120264996 T/C cg25214090 chr10:38739885 LOC399744 0.45 7.33 0.37 1.64e-12 Corneal astigmatism; LIHC cis rs9902453 0.904 rs11080115 chr17:28408070 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.6 -0.59 5.87e-34 Coffee consumption (cups per day); LIHC cis rs55665837 1.000 rs10832269 chr11:14465069 C/A cg19336497 chr11:14380999 RRAS2 -0.45 -8.29 -0.41 2.53e-15 Vitamin D levels; LIHC cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.46 7.46 0.37 7.15e-13 Bipolar disorder; LIHC cis rs988712 0.672 rs36029218 chr11:27648371 A/T cg18117895 chr11:27722066 BDNF 0.45 6.2 0.32 1.63e-9 Obesity; LIHC cis rs2857078 0.627 rs1476512 chr17:42330122 C/T cg19774624 chr17:42201019 HDAC5 0.43 5.95 0.31 6.48e-9 Red cell distribution width;Reticulocyte count; LIHC cis rs11711311 1.000 rs7633832 chr3:113472292 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.38 0.45 9.52e-19 IgG glycosylation; LIHC cis rs1865721 0.771 rs724764 chr18:73139742 C/T cg26385618 chr18:73139727 C18orf62 -0.32 -8.71 -0.43 1.34e-16 Intelligence; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16221841 chr14:77279127 ANGEL1 -0.46 -6.11 -0.31 2.65e-9 Systolic blood pressure; LIHC cis rs477895 0.713 rs1059440 chr11:63991801 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.82 -9.79 -0.47 4.15e-20 Mean platelet volume; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05533552 chr11:34074141 CAPRIN1 -0.48 -6.29 -0.32 9.91e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7129220 0.545 rs61520995 chr11:10139467 C/T cg01453529 chr11:10209919 SBF2 -0.37 -6.69 -0.34 9.33e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg13393036 chr8:95962371 TP53INP1 -0.37 -8.53 -0.42 4.71e-16 Type 2 diabetes; LIHC trans rs11039798 0.588 rs3924476 chr11:48581733 T/C cg15704280 chr7:45808275 SEPT13 0.57 6.35 0.32 6.75e-10 Axial length; LIHC cis rs1434579 0.897 rs2037903 chr19:44945136 G/A cg15540054 chr19:45004280 ZNF180 0.56 7.85 0.39 5.43e-14 Tuberculosis; LIHC cis rs2243480 1.000 rs1796228 chr7:66033084 G/A cg05590025 chr7:65112418 INTS4L2 -0.53 -5.75 -0.3 2.01e-8 Diabetic kidney disease; LIHC cis rs1552244 0.882 rs13063929 chr3:10010308 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.71 0.5 2.81e-23 Alzheimer's disease; LIHC cis rs1568889 1.000 rs16917687 chr11:28062614 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.81 0.35 4.36e-11 Bipolar disorder; LIHC cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg19318889 chr4:1322082 MAEA -0.62 -9.96 -0.47 1.1e-20 Obesity-related traits; LIHC cis rs16958440 0.708 rs62096477 chr18:44662310 G/A cg17192377 chr18:44677553 HDHD2 0.51 6.36 0.33 6.31e-10 Sitting height ratio; LIHC cis rs2033908 0.620 rs1992335 chr11:12851717 A/C cg25843174 chr11:12811716 TEAD1 -0.31 -7.18 -0.36 4.41e-12 Sitting height ratio; LIHC cis rs1395 0.744 rs11126931 chr2:27474306 C/T cg22903471 chr2:27725779 GCKR -0.4 -6.0 -0.31 5.09e-9 Blood metabolite levels; LIHC cis rs2806561 0.704 rs6426779 chr1:23310485 T/C cg19743168 chr1:23544995 NA -0.38 -7.03 -0.36 1.14e-11 Height; LIHC trans rs7246657 0.943 rs4452075 chr19:37879589 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.6 0.34 1.61e-10 Coronary artery calcification; LIHC cis rs7662987 0.517 rs2602882 chr4:100040765 C/T cg12011299 chr4:100065546 ADH4 0.63 10.34 0.49 5.59e-22 Smoking initiation; LIHC cis rs7772486 0.641 rs2253757 chr6:146199686 C/T cg23711669 chr6:146136114 FBXO30 0.63 9.59 0.46 1.9e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs1005277 0.565 rs2474565 chr10:38380828 A/G cg25427524 chr10:38739819 LOC399744 -0.64 -11.89 -0.54 1.56e-27 Extrinsic epigenetic age acceleration; LIHC trans rs911555 0.723 rs6575991 chr14:103908433 C/T cg17675199 chr6:35436792 RPL10A -0.45 -9.33 -0.45 1.39e-18 Intelligence (multi-trait analysis); LIHC cis rs3008870 0.701 rs2815367 chr1:67500762 G/A cg02640540 chr1:67518911 SLC35D1 0.44 6.89 0.35 2.65e-11 Lymphocyte percentage of white cells; LIHC cis rs9399135 0.967 rs4388304 chr6:135309597 T/A cg22676075 chr6:135203613 NA 0.4 6.46 0.33 3.53e-10 Red blood cell count; LIHC cis rs6450176 0.564 rs255759 chr5:53328549 A/G ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.5 -0.59 1.4e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg13047869 chr3:10149882 C3orf24 -0.52 -6.71 -0.34 8.31e-11 Alzheimer's disease; LIHC cis rs12451471 0.637 rs12950757 chr17:78096800 T/G cg06718696 chr17:78121285 EIF4A3 1.01 11.92 0.54 1.29e-27 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs7584330 0.666 rs72620818 chr2:238354652 G/A cg14458575 chr2:238380390 NA 0.53 7.46 0.37 7.2e-13 Prostate cancer; LIHC cis rs2278034 0.516 rs9829709 chr3:195616673 G/A cg16000393 chr3:195602323 TNK2 -0.42 -6.88 -0.35 2.95e-11 Bronchopulmonary dysplasia; LIHC trans rs116095464 0.558 rs1541822 chr5:269234 A/C cg00938859 chr5:1591904 SDHAP3 -0.54 -6.53 -0.33 2.4e-10 Breast cancer; LIHC trans rs9914544 0.545 rs8069826 chr17:18765490 G/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.59 -0.34 1.68e-10 Educational attainment (years of education); LIHC trans rs7618501 0.602 rs2624853 chr3:50128893 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.55 -8.85 -0.43 4.86e-17 Intelligence (multi-trait analysis); LIHC cis rs589448 0.902 rs642786 chr12:69758462 T/C cg19645103 chr12:69753606 YEATS4 -0.39 -5.87 -0.3 1.06e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs7131987 0.718 rs7976961 chr12:29463088 C/T cg16970926 chr12:29381810 FAR2 0.29 6.09 0.31 3.12e-9 QT interval; LIHC cis rs7296418 0.738 rs1568428 chr12:123738876 A/G cg05973401 chr12:123451056 ABCB9 -0.41 -6.13 -0.31 2.4e-9 Platelet count; LIHC cis rs72781680 1.000 rs6710426 chr2:24159288 A/G cg08917208 chr2:24149416 ATAD2B 0.84 7.77 0.39 9.29e-14 Lymphocyte counts; LIHC cis rs7223966 1.000 rs6504169 chr17:61709145 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.65 0.34 1.15e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg19318889 chr4:1322082 MAEA 0.4 6.62 0.34 1.37e-10 Obesity-related traits; LIHC cis rs5769765 0.819 rs9616377 chr22:50310880 T/C cg09182678 chr22:50328711 NA -0.43 -6.17 -0.32 1.98e-9 Schizophrenia; LIHC cis rs4689592 0.622 rs2276968 chr4:7070118 T/G cg19539972 chr4:7069911 GRPEL1 0.7 10.01 0.48 7.66e-21 Monocyte percentage of white cells; LIHC cis rs922107 0.713 rs10922669 chr1:90043240 A/G cg15422784 chr1:90023713 LRRC8B -0.47 -7.6 -0.38 2.96e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs56104184 0.775 rs55981795 chr19:49401952 A/C cg21252483 chr19:49399788 TULP2 -1.06 -12.19 -0.55 1.27e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs61990749 0.597 rs2267768 chr14:78216014 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.82 -0.39 6.67e-14 Fibroblast growth factor basic levels; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs35110281 0.755 rs4819270 chr21:45020919 G/A cg04455712 chr21:45112962 RRP1B 0.48 8.2 0.41 4.97e-15 Mean corpuscular volume; LIHC cis rs7364180 0.502 rs7290134 chr22:42321251 A/G cg04733989 chr22:42467013 NAGA -0.52 -6.01 -0.31 4.67e-9 Alzheimer's disease biomarkers; LIHC cis rs10876993 0.928 rs1689586 chr12:58079586 A/T cg15848620 chr12:58087721 OS9 -0.59 -8.1 -0.4 9.68e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs826838 0.967 rs7299170 chr12:38789536 G/A cg13010199 chr12:38710504 ALG10B 0.65 7.82 0.39 6.73e-14 Heart rate; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19855366 chr13:111267979 CARKD 0.41 6.2 0.32 1.6e-9 Lung function (FEV1/FVC); LIHC cis rs7412746 0.611 rs2280627 chr1:150935872 A/G cg17724175 chr1:150552817 MCL1 0.38 7.48 0.38 6.25e-13 Melanoma; LIHC cis rs6815814 0.950 rs5743565 chr4:38805983 T/C cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC trans rs79976124 0.879 rs10944856 chr6:66636960 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.62 0.34 1.36e-10 Type 2 diabetes; LIHC cis rs9611565 1.000 rs9611565 chr22:41767486 T/C cg06634786 chr22:41940651 POLR3H -0.65 -7.27 -0.37 2.43e-12 Vitiligo; LIHC cis rs769267 0.930 rs4808957 chr19:19567248 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.04 0.31 4.13e-9 Tonsillectomy; LIHC trans rs1499614 1.000 rs2659903 chr7:66180931 G/A cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs11098499 0.913 rs13126596 chr4:120140729 A/G cg09307838 chr4:120376055 NA 0.51 7.57 0.38 3.53e-13 Corneal astigmatism; LIHC cis rs9910055 0.530 rs2269906 chr17:42294337 G/T cg13607699 chr17:42295918 UBTF -0.62 -10.83 -0.51 1.11e-23 Total body bone mineral density; LIHC cis rs4700695 0.764 rs27701 chr5:65377526 G/C cg21114390 chr5:65439923 SFRS12 -0.5 -6.83 -0.35 3.91e-11 Facial morphology (factor 19); LIHC cis rs6089584 1.000 rs6089580 chr20:60558976 G/A cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs9359856 0.564 rs17584290 chr6:90467114 T/G cg13799429 chr6:90582589 CASP8AP2 -0.66 -5.71 -0.3 2.45e-8 Bipolar disorder; LIHC cis rs743757 1.000 rs2236987 chr3:50504546 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.53 -8.17 -0.4 6.25e-15 Diastolic blood pressure; LIHC trans rs561341 1.000 rs56903735 chr17:30254393 T/A cg20587970 chr11:113659929 NA -1.26 -10.72 -0.5 2.66e-23 Hip circumference adjusted for BMI; LIHC cis rs992157 0.710 rs6752254 chr2:219058743 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.77 12.78 0.57 7.61e-31 Colorectal cancer; LIHC trans rs13381277 0.850 rs1110157 chr18:74330649 G/A cg17352830 chr21:37617589 DOPEY2 -0.55 -6.34 -0.32 7.27e-10 Dental caries; LIHC cis rs16866061 0.962 rs72972361 chr2:225341550 G/A cg12698349 chr2:225449008 CUL3 0.73 12.54 0.56 6.38e-30 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs6951245 1.000 rs6951245 chr7:1058193 G/A cg08132940 chr7:1081526 C7orf50 -0.74 -6.36 -0.33 6.5e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1062177 0.826 rs2915879 chr5:151147442 A/G cg00977110 chr5:151150581 G3BP1 0.56 7.12 0.36 6.6e-12 Preschool internalizing problems; LIHC cis rs28735056 0.609 rs4799099 chr18:77639585 A/G cg20368463 chr18:77673604 PQLC1 0.48 8.14 0.4 7.25e-15 Schizophrenia; LIHC cis rs2279817 0.780 rs12737453 chr1:18006107 A/C cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.73 -0.39 1.2e-13 Neuroticism; LIHC cis rs801193 0.660 rs1962050 chr7:66240008 C/T cg11764359 chr7:65958608 NA -0.81 -14.26 -0.61 1.52e-36 Aortic root size; LIHC cis rs4716602 0.596 rs1996994 chr7:156159694 A/G cg16983916 chr7:156159713 NA 0.32 5.74 0.3 2.07e-8 Anti-saccade response; LIHC cis rs992157 0.798 rs7587220 chr2:219160864 C/A cg00012203 chr2:219082015 ARPC2 -0.84 -13.48 -0.59 1.61e-33 Colorectal cancer; LIHC trans rs916888 0.773 rs199535 chr17:44822662 A/G cg26692224 chr17:62915920 LRRC37A3 -0.68 -6.35 -0.32 6.79e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9326248 0.861 rs4938343 chr11:117003528 G/C cg11861562 chr11:117069780 TAGLN 0.37 5.85 0.3 1.14e-8 Blood protein levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18113084 chr3:5019494 NA 0.49 6.05 0.31 3.75e-9 Lung function (FEV1/FVC); LIHC cis rs6503525 0.628 rs4065985 chr17:38101932 G/C cg17467752 chr17:38218738 THRA 0.4 6.42 0.33 4.51e-10 Asthma; LIHC cis rs6429082 0.509 rs2246554 chr1:235520176 A/G cg26050004 chr1:235667680 B3GALNT2 0.43 6.38 0.33 5.76e-10 Adiposity; LIHC cis rs1577917 1.000 rs2324843 chr6:86617501 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.6 -0.5 7.13e-23 Response to antipsychotic treatment; LIHC cis rs3008870 1.000 rs3008855 chr1:67386204 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.89 -14.0 -0.6 1.55e-35 Lymphocyte percentage of white cells; LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs1577917 1.000 rs12201741 chr6:86602619 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.93 -0.35 2.08e-11 Response to antipsychotic treatment; LIHC cis rs6977660 0.714 rs17141882 chr7:19790217 C/T cg07541023 chr7:19748670 TWISTNB 0.49 7.28 0.37 2.36e-12 Thyroid stimulating hormone; LIHC cis rs6665290 0.669 rs3738725 chr1:227174210 T/C cg10327440 chr1:227177885 CDC42BPA -1.14 -27.87 -0.83 5.05e-90 Myeloid white cell count; LIHC cis rs2070488 1.000 rs17733640 chr3:38446742 G/A cg24069376 chr3:38537580 EXOG 0.43 7.71 0.38 1.37e-13 Electrocardiographic conduction measures; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10308682 chr20:5931622 MCM8;TRMT6 0.47 6.4 0.33 5.15e-10 Pancreatic cancer; LIHC cis rs10540 1.000 rs67912009 chr11:495057 G/T cg03352830 chr11:487213 PTDSS2 0.77 6.52 0.33 2.46e-10 Body mass index; LIHC cis rs6449957 0.801 rs6449953 chr5:67456530 A/G cg23036683 chr5:67512108 NA 0.43 6.07 0.31 3.4e-9 Cleft lip with or without cleft palate; LIHC cis rs1005277 0.579 rs2474580 chr10:38398713 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12477438 0.520 rs13031919 chr2:99848932 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.81 13.18 0.58 2.24e-32 Chronic sinus infection; LIHC cis rs8180040 0.966 rs6787422 chr3:47418509 G/T cg16586182 chr3:47516702 SCAP -0.58 -11.18 -0.52 6.16e-25 Colorectal cancer; LIHC cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg11502198 chr6:26597334 ABT1 -0.58 -9.16 -0.44 4.93e-18 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs1498316 chr1:76159198 G/A cg03433033 chr1:76189801 ACADM 0.67 9.26 0.45 2.31e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg11952622 chr19:58962976 ZNF324B 0.47 7.12 0.36 6.27e-12 Uric acid clearance; LIHC cis rs1843834 0.898 rs2014887 chr2:225520082 A/G cg22509189 chr2:225307070 NA -0.53 -7.04 -0.36 1.06e-11 IgE levels in asthmatics (D.p. specific); LIHC cis rs9534288 0.699 rs9534321 chr13:46669032 A/G cg15192986 chr13:46630673 CPB2 -0.43 -6.09 -0.31 3.06e-9 Blood protein levels; LIHC trans rs17685 0.775 rs11761172 chr7:75761547 C/T cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg20332866 chr1:100678932 DBT -0.36 -6.13 -0.31 2.48e-9 Pain; LIHC cis rs4073582 0.595 rs3016319 chr11:65981846 C/T cg14036092 chr11:66035641 RAB1B 0.44 6.46 0.33 3.67e-10 Gout; LIHC cis rs2576037 0.583 rs644731 chr18:44426877 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.98 0.51 3.15e-24 Personality dimensions; LIHC cis rs9921222 0.521 rs9935268 chr16:381562 G/C cg08923669 chr16:420230 MRPL28 -0.43 -5.73 -0.3 2.17e-8 Bone mineral density (spine);Bone mineral density; LIHC cis rs8180040 0.690 rs7640397 chr3:46989828 C/T cg02527881 chr3:46936655 PTH1R -0.35 -7.02 -0.36 1.17e-11 Colorectal cancer; LIHC cis rs10791323 0.654 rs2851119 chr11:133706382 T/C cg06766960 chr11:133703094 NA -0.53 -7.83 -0.39 6.35e-14 Childhood ear infection; LIHC cis rs11608355 0.515 rs7971160 chr12:109946751 T/A cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs763121 0.853 rs138709 chr22:39139216 C/G cg06544989 chr22:39130855 UNC84B 0.41 6.59 0.34 1.62e-10 Menopause (age at onset); LIHC cis rs7945705 0.818 rs1988708 chr11:8882893 C/A cg12365402 chr11:9010492 NRIP3 -0.24 -6.2 -0.32 1.65e-9 Hemoglobin concentration; LIHC trans rs6952808 0.692 rs56727870 chr7:2029940 T/C cg04565464 chr8:145669602 NFKBIL2 0.4 6.69 0.34 9.34e-11 Bipolar disorder and schizophrenia; LIHC cis rs2839186 0.814 rs12482209 chr21:47664275 C/G cg13012494 chr21:47604986 C21orf56 -0.41 -6.35 -0.32 6.9e-10 Testicular germ cell tumor; LIHC cis rs6963495 0.769 rs117986187 chr7:105167311 G/A cg19920283 chr7:105172520 RINT1 0.7 6.58 0.34 1.76e-10 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.99 -23.48 -0.79 2.71e-73 Prudent dietary pattern; LIHC cis rs11229555 0.645 rs12289985 chr11:58185436 C/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs8016982 0.662 rs2288498 chr14:81660710 T/C cg01989461 chr14:81687754 GTF2A1 0.52 9.17 0.44 4.56e-18 Schizophrenia; LIHC cis rs701145 0.556 rs191651 chr3:153973887 T/G cg16511985 chr3:153974050 SGEF 0.43 9.13 0.44 5.95e-18 Coronary artery disease; LIHC cis rs172166 0.694 rs203877 chr6:28048624 T/C cg23485639 chr6:28045615 ZNF165 0.39 6.13 0.31 2.42e-9 Cardiac Troponin-T levels; LIHC cis rs240764 0.717 rs1039031 chr6:101161812 A/G cg09795085 chr6:101329169 ASCC3 0.46 6.64 0.34 1.26e-10 Neuroticism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21051989 chr6:90121833 RRAGD 0.5 6.58 0.34 1.73e-10 Lung function (FEV1/FVC); LIHC cis rs611744 0.604 rs13248461 chr8:109285833 C/T cg18478394 chr8:109455254 TTC35 0.43 7.51 0.38 5.1e-13 Dupuytren's disease; LIHC cis rs748404 0.660 rs509306 chr15:43715171 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.73 0.39 1.19e-13 Lung cancer; LIHC cis rs4919087 0.561 rs61861820 chr10:98998974 G/A cg25902810 chr10:99078978 FRAT1 -0.53 -5.93 -0.31 7.23e-9 Monocyte count; LIHC cis rs6570726 0.791 rs9497357 chr6:145912888 G/A cg23711669 chr6:146136114 FBXO30 0.65 10.94 0.51 4.22e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs34172651 0.517 rs7204288 chr16:24784531 A/G cg00339695 chr16:24857497 SLC5A11 0.7 10.37 0.49 4.45e-22 Intelligence (multi-trait analysis); LIHC trans rs17685 0.753 rs2286830 chr7:75693963 C/T cg19862616 chr7:65841803 NCRNA00174 -0.93 -19.29 -0.72 1.3e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs798554 1.000 rs798550 chr7:2760609 A/G cg19717773 chr7:2847554 GNA12 -0.42 -6.68 -0.34 9.87e-11 Height; LIHC cis rs1215050 0.765 rs181521 chr4:98745728 A/C cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9503598 0.636 rs7745968 chr6:3467745 G/T cg00476032 chr6:3446245 SLC22A23 0.4 7.77 0.39 9.14e-14 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs4423214 0.840 rs1540127 chr11:71179038 G/A cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC trans rs66887589 0.616 rs7659403 chr4:120207254 T/A cg25214090 chr10:38739885 LOC399744 0.43 6.86 0.35 3.26e-11 Diastolic blood pressure; LIHC cis rs1023500 0.505 rs134888 chr22:42674281 C/T cg04733989 chr22:42467013 NAGA 0.42 6.27 0.32 1.09e-9 Schizophrenia; LIHC cis rs7208859 0.673 rs450585 chr17:28951039 G/A cg13385521 chr17:29058706 SUZ12P 0.57 5.76 0.3 1.83e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3806843 0.966 rs2563255 chr5:140142547 T/C cg19875535 chr5:140030758 IK -0.37 -5.98 -0.31 5.72e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2836974 0.627 rs8127986 chr21:40687211 A/T cg17971929 chr21:40555470 PSMG1 -0.46 -6.99 -0.35 1.43e-11 Cognitive function; LIHC cis rs11958404 0.615 rs6884132 chr5:157437035 G/A cg05962755 chr5:157440814 NA 0.61 7.67 0.38 1.77e-13 IgG glycosylation; LIHC trans rs561341 1.000 rs1681718 chr17:30296445 G/A cg20587970 chr11:113659929 NA -1.38 -11.72 -0.54 6.87e-27 Hip circumference adjusted for BMI; LIHC cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg25894440 chr7:65020034 NA 0.55 6.55 0.33 2.17e-10 Diabetic kidney disease; LIHC cis rs9303280 0.806 rs12709365 chr17:38027400 A/G cg11212589 chr17:38028394 ZPBP2 0.35 7.13 0.36 5.88e-12 Self-reported allergy; LIHC cis rs7208859 0.623 rs9912440 chr17:29148772 A/G cg13385521 chr17:29058706 SUZ12P 0.77 7.77 0.39 9.57e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6952808 0.601 rs3778978 chr7:2159817 A/G cg02951883 chr7:2050386 MAD1L1 -0.65 -10.69 -0.5 3.24e-23 Bipolar disorder and schizophrenia; LIHC cis rs10508774 1.000 rs61299190 chr10:32859519 A/G cg01819863 chr10:32635814 EPC1 0.65 6.01 0.31 4.73e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11123170 0.640 rs2863240 chr2:113970116 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.47 -5.79 -0.3 1.63e-8 Renal function-related traits (BUN); LIHC trans rs916888 0.610 rs199529 chr17:44837217 A/C cg16836995 chr17:43662488 NA -0.69 -7.24 -0.36 3.06e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2997447 0.655 rs2275950 chr1:26385003 T/C cg19633962 chr1:26362018 EXTL1 -0.64 -7.89 -0.39 4e-14 QRS complex (12-leadsum); LIHC cis rs66569888 0.581 rs17271098 chr2:106692818 A/G cg16099169 chr2:106886729 NA 0.75 8.16 0.4 6.3e-15 Facial morphology (factor 23); LIHC cis rs1568889 0.838 rs7952717 chr11:28261658 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.14 0.61 4.64e-36 Bipolar disorder; LIHC cis rs2439831 1.000 rs28666488 chr15:43741090 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.78 13.14 0.58 3.32e-32 Lung cancer in ever smokers; LIHC cis rs2273156 1.000 rs35797365 chr14:35452759 A/G cg16230307 chr14:35515116 FAM177A1 -0.4 -5.95 -0.31 6.57e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs853679 0.517 rs9393886 chr6:28050039 T/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs17826219 0.706 rs61643715 chr17:29057762 A/G cg13385521 chr17:29058706 SUZ12P 0.85 8.45 0.42 8.72e-16 Body mass index; LIHC cis rs7772486 0.790 rs11760 chr6:146205973 G/T cg05347473 chr6:146136440 FBXO30 0.37 5.94 0.31 7.21e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg11644478 chr21:40555479 PSMG1 -0.39 -6.08 -0.31 3.2e-9 Cognitive function; LIHC cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs972578 0.967 rs2068944 chr22:43356442 T/G cg01576275 chr22:43409880 NA -0.33 -5.76 -0.3 1.87e-8 Mean platelet volume; LIHC cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg24549020 chr5:56110836 MAP3K1 0.47 6.14 0.32 2.27e-9 Initial pursuit acceleration; LIHC cis rs8180040 0.966 rs13064843 chr3:47415467 C/T cg16586182 chr3:47516702 SCAP -0.58 -11.23 -0.52 4.06e-25 Colorectal cancer; LIHC cis rs9649213 0.502 rs6465680 chr7:98005778 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.84 -0.3 1.19e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs2727020 0.729 rs4980439 chr11:49342246 G/C cg03929089 chr4:120376271 NA -0.84 -14.68 -0.62 3.56e-38 Coronary artery disease; LIHC cis rs4517514 0.509 rs12276499 chr11:89855565 C/G cg05041596 chr11:89867385 NAALAD2 0.41 6.37 0.33 5.92e-10 Trans fatty acid levels; LIHC cis rs611744 0.560 rs58605513 chr8:109279122 A/C cg18478394 chr8:109455254 TTC35 0.44 7.67 0.38 1.76e-13 Dupuytren's disease; LIHC cis rs8180040 0.903 rs11710013 chr3:47296921 T/C cg16586182 chr3:47516702 SCAP -0.52 -9.36 -0.45 1.09e-18 Colorectal cancer; LIHC cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg05590025 chr7:65112418 INTS4L2 -0.62 -6.49 -0.33 2.94e-10 Diabetic kidney disease; LIHC cis rs11229555 0.645 rs11601296 chr11:58423297 A/G cg15696309 chr11:58395628 NA -0.68 -6.4 -0.33 5.04e-10 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7095607 0.560 rs2634709 chr10:69925789 C/T cg18986048 chr10:69913749 MYPN 0.48 7.11 0.36 6.77e-12 Lung function (FVC); LIHC cis rs9457247 0.967 rs382009 chr6:167403121 G/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.04 -0.51 1.98e-24 Crohn's disease; LIHC cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg12751644 chr20:60527061 NA -0.37 -6.06 -0.31 3.59e-9 Body mass index; LIHC cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC trans rs11098499 0.690 rs34818745 chr4:120257055 T/C cg25214090 chr10:38739885 LOC399744 0.57 8.79 0.43 7.36e-17 Corneal astigmatism; LIHC cis rs72781680 0.898 rs7589440 chr2:24038595 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg18876405 chr7:65276391 NA 0.34 5.94 0.31 7.21e-9 Calcium levels; LIHC cis rs875971 0.893 rs62465470 chr7:65601218 T/C cg18876405 chr7:65276391 NA -0.38 -6.66 -0.34 1.08e-10 Aortic root size; LIHC cis rs6459804 0.844 rs76501205 chr7:157508941 A/T cg05731713 chr7:157510257 PTPRN2 0.23 6.36 0.33 6.32e-10 Bipolar disorder and schizophrenia; LIHC cis rs35110281 0.774 rs2838327 chr21:45018566 A/C cg01579765 chr21:45077557 HSF2BP -0.34 -6.48 -0.33 3.21e-10 Mean corpuscular volume; LIHC cis rs55665837 0.540 rs4757261 chr11:14669802 C/A cg16394018 chr11:14927549 NA 0.4 5.72 0.3 2.27e-8 Vitamin D levels; LIHC cis rs2239547 0.522 rs9865094 chr3:52985319 G/C cg11645453 chr3:52864694 ITIH4 -0.23 -5.8 -0.3 1.53e-8 Schizophrenia; LIHC cis rs7131987 0.934 rs2216854 chr12:29423460 G/A cg00204748 chr12:29376779 FAR2 0.43 8.06 0.4 1.33e-14 QT interval; LIHC cis rs5753618 0.561 rs737887 chr22:31696615 A/G cg22777020 chr22:31556080 RNF185 -0.55 -6.35 -0.32 6.77e-10 Colorectal cancer; LIHC cis rs4332037 0.624 rs11764124 chr7:1891723 C/G cg23422044 chr7:1970798 MAD1L1 -0.54 -6.66 -0.34 1.1e-10 Bipolar disorder; LIHC cis rs7224685 0.569 rs34357603 chr17:4008760 G/A cg11204139 chr17:3907470 NA 0.58 6.73 0.34 7.2e-11 Type 2 diabetes; LIHC cis rs7872515 0.887 rs7029539 chr9:94864322 A/G cg01248375 chr9:94877805 SPTLC1 0.54 8.16 0.4 6.26e-15 Bipolar disorder and schizophrenia; LIHC cis rs4555082 0.834 rs28489970 chr14:105748862 T/C cg10792982 chr14:105748885 BRF1 0.45 6.06 0.31 3.66e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.6 0.46 1.72e-19 Electroencephalogram traits; LIHC cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg26818010 chr10:134567672 INPP5A -0.76 -9.13 -0.44 5.91e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2439831 0.850 rs3742982 chr15:44176681 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.64 8.87 0.43 4.13e-17 Lung cancer in ever smokers; LIHC cis rs2404602 0.583 rs2456076 chr15:76557553 T/G cg23625390 chr15:77176239 SCAPER -0.35 -6.15 -0.32 2.2e-9 Blood metabolite levels; LIHC cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.92 0.3 7.88e-9 Menopause (age at onset); LIHC cis rs950169 1.000 rs11638297 chr15:84782417 A/C cg17507749 chr15:85114479 UBE2QP1 0.75 7.82 0.39 6.76e-14 Schizophrenia; LIHC cis rs16958440 1.000 rs12326600 chr18:44596497 C/T cg17192377 chr18:44677553 HDHD2 0.57 6.11 0.31 2.72e-9 Sitting height ratio; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24258806 chr11:14380041 RRAS2 0.49 6.53 0.33 2.42e-10 Lung function (FEV1/FVC); LIHC cis rs9549367 0.789 rs9549701 chr13:113881752 G/C cg18105134 chr13:113819100 PROZ -0.67 -11.66 -0.53 1.09e-26 Platelet distribution width; LIHC cis rs2239547 0.522 rs2710345 chr3:52976075 T/C cg11645453 chr3:52864694 ITIH4 -0.23 -5.78 -0.3 1.71e-8 Schizophrenia; LIHC cis rs12474201 0.928 rs35825831 chr2:46932544 T/G cg06386533 chr2:46925753 SOCS5 0.74 8.23 0.41 3.88e-15 Height; LIHC cis rs6722750 0.783 rs4671550 chr2:64389314 T/A cg22352474 chr2:64371530 PELI1 0.47 6.86 0.35 3.22e-11 Neuroticism; LIHC cis rs75064307 0.798 rs2290601 chr3:108112760 C/T cg03329597 chr3:108125523 MYH15 0.5 6.68 0.34 9.97e-11 Intelligence (multi-trait analysis); LIHC cis rs9381040 0.599 rs2057001 chr6:41022947 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.43 -6.84 -0.35 3.74e-11 Alzheimer's disease (late onset); LIHC cis rs4423214 0.840 rs1619577 chr11:71181485 C/T cg05163923 chr11:71159392 DHCR7 -0.61 -8.09 -0.4 1.03e-14 Vitamin D levels; LIHC cis rs9399135 0.967 rs4376365 chr6:135307740 T/C cg22676075 chr6:135203613 NA 0.4 6.44 0.33 3.96e-10 Red blood cell count; LIHC cis rs2070488 0.965 rs1065800 chr3:38566480 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.48 -0.62 2.14e-37 Electrocardiographic conduction measures; LIHC cis rs12086130 0.773 rs72906827 chr1:51482411 C/G cg07174182 chr1:51127561 FAF1 -0.81 -9.0 -0.44 1.62e-17 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs7945718 0.621 rs6485977 chr11:12678387 C/T cg25843174 chr11:12811716 TEAD1 0.34 7.87 0.39 4.59e-14 Educational attainment (years of education); LIHC cis rs7429990 0.932 rs2361684 chr3:48152618 G/C cg11946769 chr3:48343235 NME6 -0.47 -6.24 -0.32 1.28e-9 Educational attainment (years of education); LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg26338869 chr17:61819248 STRADA 0.59 8.71 0.43 1.31e-16 Prudent dietary pattern; LIHC cis rs74181299 0.964 rs2540949 chr2:65284231 A/T cg05010058 chr2:65284262 CEP68 0.4 6.82 0.35 4.1e-11 Pulse pressure; LIHC trans rs61931739 0.517 rs10844802 chr12:34231001 C/A cg26384229 chr12:38710491 ALG10B 0.57 7.38 0.37 1.2e-12 Morning vs. evening chronotype; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg23131131 chr22:24373011 LOC391322 -0.54 -7.37 -0.37 1.25e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs8002861 0.781 rs7322781 chr13:44442238 T/C cg17145862 chr1:211918768 LPGAT1 0.58 10.82 0.5 1.17e-23 Leprosy; LIHC cis rs244293 0.760 rs12952166 chr17:53005586 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.53 -0.33 2.32e-10 Menarche (age at onset); LIHC cis rs9534288 0.552 rs2840241 chr13:46658903 T/G cg15192986 chr13:46630673 CPB2 -0.44 -6.38 -0.33 5.79e-10 Blood protein levels; LIHC cis rs911119 0.955 rs6048930 chr20:23592492 T/C cg16589663 chr20:23618590 CST3 0.71 7.3 0.37 2.07e-12 Chronic kidney disease; LIHC cis rs34638657 0.536 rs2967327 chr16:82188657 C/T cg07918374 chr16:82182319 MPHOSPH6 0.32 6.11 0.31 2.7e-9 Lung adenocarcinoma; LIHC cis rs2153535 0.580 rs1932282 chr6:8477330 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.24 0.41 3.69e-15 Height; LIHC cis rs12477438 0.520 rs7604557 chr2:99747829 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs7635838 0.617 rs346084 chr3:11281159 C/T cg00170343 chr3:11313890 ATG7 0.59 9.37 0.45 9.94e-19 HDL cholesterol; LIHC cis rs6089584 0.853 rs1740367 chr20:60574834 C/T cg23262073 chr20:60523788 NA -0.29 -5.79 -0.3 1.58e-8 Body mass index; LIHC cis rs17001868 0.568 rs9611329 chr22:40792038 G/T cg07138101 chr22:40742427 ADSL 0.56 6.64 0.34 1.27e-10 Mammographic density (dense area); LIHC cis rs311392 0.554 rs311423 chr8:55104694 G/A cg11783602 chr8:55087084 NA -0.31 -6.21 -0.32 1.53e-9 Pelvic organ prolapse (moderate/severe); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05895930 chr17:43212841 ACBD4 -0.53 -6.16 -0.32 2.08e-9 Systolic blood pressure; LIHC cis rs9818758 0.607 rs35673421 chr3:49139406 G/A cg07636037 chr3:49044803 WDR6 -0.81 -8.4 -0.41 1.2e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs17685 0.753 rs13240967 chr7:75658197 C/T cg19862616 chr7:65841803 NCRNA00174 -0.91 -18.65 -0.71 4.85e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7659604 0.539 rs7686200 chr4:122764553 C/T cg19748678 chr4:122722346 EXOSC9 0.66 11.35 0.52 1.44e-25 Type 2 diabetes; LIHC cis rs11212737 0.765 rs2624144 chr11:108520134 A/T cg22776369 chr11:108536276 DDX10 0.37 6.2 0.32 1.62e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg05564831 chr3:52568323 NT5DC2 0.34 5.81 0.3 1.42e-8 Bipolar disorder; LIHC cis rs10845606 0.505 rs10845604 chr12:12832734 A/G cg04607235 chr12:12878440 APOLD1 0.43 6.24 0.32 1.31e-9 Systemic lupus erythematosus; LIHC cis rs9381040 0.599 rs2057001 chr6:41022947 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.37 -6.0 -0.31 5.12e-9 Alzheimer's disease (late onset); LIHC cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg20684491 chr1:25596433 NA 0.29 5.92 0.3 7.81e-9 Erythrocyte sedimentation rate; LIHC cis rs35146811 0.586 rs6964754 chr7:99589404 G/A cg22906224 chr7:99728672 NA 0.48 6.43 0.33 4.24e-10 Coronary artery disease; LIHC cis rs60871478 0.947 rs4074610 chr7:791755 G/A cg27478167 chr7:817139 HEATR2 -0.4 -5.79 -0.3 1.56e-8 Cerebrospinal P-tau181p levels; LIHC trans rs2565065 0.614 rs2241654 chr8:27293989 G/A cg05556461 chr5:71018061 NA 0.3 6.1 0.31 2.83e-9 Schizophrenia; LIHC cis rs2235642 0.750 rs763152 chr16:1658056 T/C cg03034668 chr16:1723424 CRAMP1L -0.39 -6.88 -0.35 2.88e-11 Coronary artery disease; LIHC cis rs4919694 1.000 rs12261040 chr10:104665397 T/C cg04362960 chr10:104952993 NT5C2 0.79 7.91 0.39 3.58e-14 Arsenic metabolism; LIHC trans rs1005277 0.579 rs2749612 chr10:38488610 G/A cg17830980 chr10:43048298 ZNF37B -0.52 -10.18 -0.48 2e-21 Extrinsic epigenetic age acceleration; LIHC cis rs2952156 0.652 rs11869286 chr17:37813856 C/G cg00129232 chr17:37814104 STARD3 -0.59 -11.46 -0.53 6.21e-26 Asthma; LIHC trans rs1728785 1.000 rs864742 chr16:68575309 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.78e-9 Ulcerative colitis; LIHC trans rs66573146 0.572 rs67922134 chr4:6955772 G/A cg07817883 chr1:32538562 TMEM39B 1.02 9.01 0.44 1.54e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs62179067 0.708 rs7588765 chr2:179932838 T/G cg20701897 chr2:179586761 TTN 0.49 5.83 0.3 1.32e-8 Late-onset Alzheimer's disease; LIHC cis rs11622475 0.580 rs36026329 chr14:104351661 T/A cg12183467 chr14:104352244 NA -0.5 -7.3 -0.37 2.01e-12 Bipolar disorder; LIHC cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg12463550 chr7:65579703 CRCP 0.69 7.2 0.36 3.93e-12 Diabetic kidney disease; LIHC cis rs11864453 0.611 rs9926927 chr16:72130556 G/T cg16558253 chr16:72132732 DHX38 -0.45 -7.31 -0.37 1.95e-12 Fibrinogen levels; LIHC cis rs240764 0.717 rs6916468 chr6:101160325 G/C cg09795085 chr6:101329169 ASCC3 -0.47 -6.79 -0.34 4.83e-11 Neuroticism; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.7 0.62 3e-38 Prudent dietary pattern; LIHC cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg03806693 chr22:41940476 POLR3H -1.1 -13.13 -0.58 3.71e-32 Vitiligo; LIHC cis rs17685 0.753 rs1637037 chr7:75692927 C/T cg16684958 chr7:75615977 POR 0.51 8.61 0.42 2.78e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.82 0.35 4.07e-11 Gut microbiome composition (summer); LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg04025307 chr7:1156635 C7orf50 0.58 10.12 0.48 3.02e-21 Longevity;Endometriosis; LIHC trans rs4820294 0.669 rs12628135 chr22:38065655 A/G cg19894588 chr14:64061835 NA -0.46 -7.35 -0.37 1.46e-12 Fat distribution (HIV); LIHC cis rs2932538 0.922 rs12136781 chr1:113090655 C/T cg22162597 chr1:113214053 CAPZA1 0.7 10.71 0.5 2.76e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7805747 0.961 rs10224002 chr7:151415041 C/T cg17611936 chr7:151411526 PRKAG2 -0.5 -5.79 -0.3 1.6e-8 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); LIHC cis rs4808199 0.948 rs12982276 chr19:19459800 T/C cg03709012 chr19:19516395 GATAD2A 1.02 17.35 0.68 8.06e-49 Nonalcoholic fatty liver disease; LIHC cis rs754466 0.651 rs11002316 chr10:79617511 C/G cg17075019 chr10:79541650 NA -0.76 -11.66 -0.53 1.11e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6977660 1.000 rs5017196 chr7:19819983 T/C cg07541023 chr7:19748670 TWISTNB 0.36 5.74 0.3 2.1e-8 Thyroid stimulating hormone; LIHC cis rs7246657 0.943 rs12709813 chr19:37844983 G/A cg23950597 chr19:37808831 NA -0.44 -5.97 -0.31 5.93e-9 Coronary artery calcification; LIHC cis rs35306767 0.903 rs11253488 chr10:922482 G/C cg26597838 chr10:835615 NA 1.12 13.19 0.58 2.16e-32 Eosinophil percentage of granulocytes; LIHC cis rs75908454 1.000 rs75667803 chr6:169998285 G/A cg19338460 chr6:170058176 WDR27 -0.91 -8.79 -0.43 7.39e-17 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg23758822 chr17:41437982 NA 0.94 17.57 0.69 1.1e-49 Menopause (age at onset); LIHC cis rs7613875 0.620 rs11721204 chr3:49982765 C/T cg24110177 chr3:50126178 RBM5 -0.52 -8.41 -0.41 1.09e-15 Body mass index; LIHC cis rs10463316 0.832 rs1019467 chr5:150734323 A/G cg03212797 chr5:150827313 SLC36A1 -0.47 -7.2 -0.36 3.74e-12 Metabolite levels (Pyroglutamine); LIHC trans rs10050311 0.790 rs61651372 chr4:87834056 C/T cg04118154 chr1:45140072 C1orf228;TMEM53 -0.48 -6.18 -0.32 1.81e-9 Insulin-related traits; LIHC cis rs7592578 0.766 rs62181052 chr2:191387858 A/G cg27211696 chr2:191398769 TMEM194B -0.64 -8.43 -0.41 9.73e-16 Diastolic blood pressure; LIHC cis rs919433 0.889 rs787998 chr2:198216092 A/G cg10820045 chr2:198174542 NA 0.52 8.68 0.42 1.7e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs74181299 0.890 rs2540950 chr2:65279223 C/T cg05010058 chr2:65284262 CEP68 0.41 6.86 0.35 3.18e-11 Pulse pressure; LIHC cis rs950776 0.518 rs28438420 chr15:78836288 A/T cg22563815 chr15:78856949 CHRNA5 -0.28 -5.91 -0.3 8.26e-9 Sudden cardiac arrest; LIHC cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg17971929 chr21:40555470 PSMG1 -0.44 -6.65 -0.34 1.19e-10 Cognitive function; LIHC cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg11301795 chr4:187892539 NA -0.26 -6.76 -0.34 5.79e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2455799 0.613 rs2455813 chr3:15735051 C/G cg12698662 chr3:15914712 MIR563 -0.36 -6.66 -0.34 1.1e-10 Mean platelet volume; LIHC cis rs11758351 0.518 rs78871852 chr6:26221566 A/T cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg13944838 chr5:179740914 GFPT2 -0.55 -7.64 -0.38 2.14e-13 Height; LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg14004847 chr7:1930337 MAD1L1 0.56 8.51 0.42 5.68e-16 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg11764359 chr7:65958608 NA 0.59 6.17 0.32 1.98e-9 Diabetic kidney disease; LIHC cis rs748404 0.578 rs2012467 chr15:43690565 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.53 9.27 0.45 2.12e-18 Lung cancer; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg07335843 chr2:133030691 NA 0.32 6.59 0.34 1.68e-10 Bilirubin levels; LIHC cis rs2737618 0.674 rs2821332 chr1:200085714 A/T cg21825944 chr1:200113062 NR5A2 -0.5 -8.84 -0.43 5.05e-17 Uric acid levels; LIHC cis rs1023500 0.596 rs5758562 chr22:42448238 C/G cg00645731 chr22:42541494 CYP2D7P1 0.41 6.35 0.32 7.02e-10 Schizophrenia; LIHC cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg19016816 chr7:1267987 NA 0.27 5.78 0.3 1.72e-8 Bipolar disorder and schizophrenia; LIHC cis rs372883 0.600 rs2832293 chr21:30738872 C/G cg08807101 chr21:30365312 RNF160 0.51 5.95 0.31 6.58e-9 Pancreatic cancer; LIHC cis rs903552 1.000 rs12908406 chr15:102004046 C/T cg00659931 chr15:102010125 PCSK6 -0.48 -6.52 -0.33 2.46e-10 Diabetic kidney disease; LIHC cis rs1008375 0.931 rs10019482 chr4:17578079 G/A cg16339924 chr4:17578868 LAP3 0.45 6.16 0.32 2.07e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs77633900 0.614 rs279999 chr15:76945466 C/T cg21673338 chr15:77095150 SCAPER -0.5 -7.39 -0.37 1.11e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs10744422 0.800 rs2343110 chr12:123343571 T/G cg25930673 chr12:123319894 HIP1R -0.95 -12.68 -0.57 1.85e-30 Schizophrenia; LIHC cis rs9733 0.818 rs11204702 chr1:150663507 C/A cg17724175 chr1:150552817 MCL1 -0.38 -7.86 -0.39 5.21e-14 Tonsillectomy; LIHC cis rs4638749 0.654 rs6761157 chr2:108816885 A/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.71 -0.34 8.07e-11 Blood pressure; LIHC cis rs1801251 0.964 rs10933411 chr2:233706847 A/G cg08000102 chr2:233561755 GIGYF2 -0.76 -11.51 -0.53 3.76e-26 Coronary artery disease; LIHC cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg21644426 chr2:191273491 MFSD6 0.54 7.55 0.38 3.92e-13 Pulse pressure; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg12331332 chr10:115439884 CASP7 0.45 6.36 0.33 6.49e-10 Alopecia areata; LIHC cis rs4654748 0.507 rs10799702 chr1:21821880 A/G cg20417195 chr1:21767127 NBPF3 -0.41 -5.92 -0.31 7.71e-9 Folate pathway vitamin levels; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg03414471 chr3:11600889 VGLL4 0.37 6.06 0.31 3.57e-9 Oropharynx cancer; LIHC cis rs9911578 1.000 rs2055779 chr17:57030561 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.79 0.69 1.4e-50 Intelligence (multi-trait analysis); LIHC cis rs7399018 0.739 rs6580811 chr12:51612501 T/C cg12163867 chr12:51592794 POU6F1 -0.35 -5.93 -0.31 7.35e-9 Cisplatin-induced ototoxicity; LIHC cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg12311346 chr5:56204834 C5orf35 -0.56 -7.31 -0.37 1.88e-12 Initial pursuit acceleration; LIHC cis rs10751667 0.666 rs10794347 chr11:939863 G/A ch.11.42038R chr11:967971 AP2A2 0.55 10.04 0.48 5.67e-21 Alzheimer's disease (late onset); LIHC cis rs7100689 0.646 rs7899791 chr10:82091950 A/T cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs17270561 0.943 rs4478398 chr6:25694684 T/C cg17691542 chr6:26056736 HIST1H1C 0.65 7.19 0.36 4.2e-12 Iron status biomarkers; LIHC cis rs1816752 0.646 rs2862905 chr13:25059280 G/A cg22771759 chr13:24902376 NA -0.27 -5.74 -0.3 2.04e-8 Obesity-related traits; LIHC cis rs2637266 0.714 rs1965156 chr10:78450559 G/A cg18941641 chr10:78392320 NA 0.27 5.93 0.31 7.46e-9 Pulmonary function; LIHC cis rs7666738 0.791 rs13111960 chr4:98976851 C/T cg05340658 chr4:99064831 C4orf37 0.72 13.24 0.58 1.37e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs7772486 0.790 rs2814879 chr6:146201743 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.58 0.53 2.23e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg06873352 chr17:61820015 STRADA 0.61 9.47 0.46 4.75e-19 Height; LIHC cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg26818010 chr10:134567672 INPP5A -0.79 -9.59 -0.46 1.84e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3749237 0.595 rs17595772 chr3:49409704 G/A cg03060546 chr3:49711283 APEH 0.58 9.54 0.46 2.7e-19 Resting heart rate; LIHC cis rs12291225 0.585 rs4757250 chr11:14375683 C/A cg19336497 chr11:14380999 RRAS2 -0.67 -14.04 -0.6 1.12e-35 Sense of smell; LIHC cis rs4780401 0.527 rs4780402 chr16:11839809 C/T cg01061890 chr16:11836724 TXNDC11 -0.55 -8.7 -0.43 1.4e-16 Rheumatoid arthritis; LIHC cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg03264133 chr6:25882463 NA -0.62 -8.73 -0.43 1.12e-16 Blood metabolite levels; LIHC cis rs4423214 0.592 rs10898211 chr11:71210677 T/C cg05163923 chr11:71159392 DHCR7 -0.56 -6.9 -0.35 2.57e-11 Vitamin D levels; LIHC cis rs765787 0.530 rs1648286 chr15:45517386 G/C cg25801113 chr15:45476975 SHF 0.38 6.39 0.33 5.42e-10 Uric acid levels; LIHC cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg20090690 chr10:134436459 INPP5A -0.44 -5.94 -0.31 6.98e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 13.94 0.6 2.81e-35 Prudent dietary pattern; LIHC cis rs7917772 0.545 rs10786681 chr10:104317357 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.88 0.39 4.45e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9790314 0.663 rs778653 chr3:160716041 G/T cg03342759 chr3:160939853 NMD3 -0.58 -8.0 -0.4 1.94e-14 Morning vs. evening chronotype; LIHC trans rs66573146 0.831 rs56081162 chr4:6989718 C/T cg07817883 chr1:32538562 TMEM39B 1.18 9.36 0.45 1.08e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs2290405 0.527 rs935965 chr4:928684 T/C cg04824913 chr4:887549 GAK 0.53 8.18 0.4 5.72e-15 Systemic sclerosis; LIHC cis rs4819052 0.851 rs4819044 chr21:46660118 G/A cg22633049 chr21:46681294 NA -0.37 -6.31 -0.32 8.65e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg00091569 chr3:40428383 ENTPD3 -0.35 -6.09 -0.31 2.96e-9 Renal cell carcinoma; LIHC cis rs7223966 0.515 rs2727315 chr17:61961458 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.53 6.3 0.32 9.08e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs796364 0.760 rs55906940 chr2:201049386 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.75 -8.22 -0.41 4.32e-15 Schizophrenia; LIHC cis rs12477438 0.765 rs10193039 chr2:99692373 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.32 -0.37 1.78e-12 Chronic sinus infection; LIHC cis rs9291683 0.595 rs11731110 chr4:10037346 T/C cg11266682 chr4:10021025 SLC2A9 0.35 7.44 0.37 8.24e-13 Bone mineral density; LIHC cis rs68170813 0.559 rs6971774 chr7:106834139 A/G cg02696742 chr7:106810147 HBP1 -0.49 -5.8 -0.3 1.51e-8 Coronary artery disease; LIHC cis rs10504229 1.000 rs58608483 chr8:58195269 T/G cg20607798 chr8:58055168 NA 0.54 6.4 0.33 5.15e-10 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.623 rs9911997 chr17:29124648 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4474465 1.000 rs10899521 chr11:78184560 T/A cg27205649 chr11:78285834 NARS2 -0.38 -5.92 -0.3 7.93e-9 Alzheimer's disease (survival time); LIHC cis rs8072100 0.967 rs11656855 chr17:45714655 C/T cg08085267 chr17:45401833 C17orf57 0.41 6.08 0.31 3.26e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg19539972 chr4:7069911 GRPEL1 0.64 9.54 0.46 2.88e-19 Monocyte percentage of white cells; LIHC cis rs35160687 0.623 rs4832263 chr2:86485157 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.36 5.74 0.3 2.07e-8 Night sleep phenotypes; LIHC trans rs116095464 0.558 rs28635197 chr5:279071 T/C cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs826838 0.967 rs4768329 chr12:39129394 T/C cg13010199 chr12:38710504 ALG10B -0.41 -5.78 -0.3 1.66e-8 Heart rate; LIHC cis rs853679 0.517 rs9380052 chr6:28064623 A/G cg16479474 chr6:28041457 NA 0.46 6.68 0.34 9.76e-11 Depression; LIHC cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.29 -5.83 -0.3 1.26e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs6089584 0.854 rs6061407 chr20:60622048 A/C cg06108461 chr20:60628389 TAF4 -1.0 -17.61 -0.69 7.12e-50 Body mass index; LIHC cis rs17106184 1.000 rs12064411 chr1:51220291 A/G cg07174182 chr1:51127561 FAF1 -0.63 -6.86 -0.35 3.32e-11 Type 2 diabetes; LIHC cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.33 0.45 1.39e-18 Platelet count; LIHC cis rs4917300 0.605 rs7820768 chr8:143110823 C/T cg25363559 chr8:143086065 NA -0.24 -7.55 -0.38 3.99e-13 Amyotrophic lateral sclerosis; LIHC cis rs9733 0.650 rs2048558 chr1:150571730 A/G cg18016565 chr1:150552671 MCL1 -0.54 -11.14 -0.52 8.75e-25 Tonsillectomy; LIHC cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.26 0.52 3.09e-25 Colorectal cancer; LIHC cis rs7512552 0.839 rs1260459 chr1:150348253 T/G cg15654264 chr1:150340011 RPRD2 0.68 11.18 0.52 6.33e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9948 0.655 rs62156212 chr2:97399096 C/T cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7914558 0.646 rs4363528 chr10:104655515 A/G cg15744005 chr10:104629667 AS3MT -0.35 -7.38 -0.37 1.22e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14166365 chr9:126165469 DENND1A;MIR601 0.45 7.7 0.38 1.52e-13 Longevity; LIHC cis rs9543976 1.000 rs73223968 chr13:76141721 C/A cg01531495 chr13:76123901 UCHL3 -0.52 -6.16 -0.32 1.99e-9 Diabetic retinopathy; LIHC cis rs3020736 0.500 rs6002618 chr22:42507859 G/C cg15557168 chr22:42548783 NA 0.43 6.78 0.34 5.3e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs13217239 0.646 rs10946898 chr6:27003884 T/C cg18867708 chr6:26865862 GUSBL1 0.51 7.78 0.39 8.55e-14 Schizophrenia; LIHC cis rs588177 1.000 rs588177 chr11:64024056 C/A cg24431193 chr11:63883947 FLRT1;MACROD1 -0.46 -6.83 -0.35 3.83e-11 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs57221529 0.713 rs12521091 chr5:590710 G/T cg25482853 chr8:67687455 SGK3 0.64 6.16 0.32 2.05e-9 Lung disease severity in cystic fibrosis; LIHC cis rs9911578 1.000 rs302854 chr17:56683612 G/A cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs2976388 0.647 rs2585138 chr8:143808951 C/T cg06565975 chr8:143823917 SLURP1 0.34 6.76 0.34 6.05e-11 Urinary tract infection frequency; LIHC cis rs1552244 0.554 rs6796411 chr3:10010681 G/A cg21531657 chr3:10005747 TMEM111 0.4 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg27572855 chr1:25598939 RHD -0.39 -8.26 -0.41 3.19e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs1371867 0.846 rs1788182 chr8:101334620 C/T cg06636551 chr8:101224915 SPAG1 -0.47 -8.72 -0.43 1.26e-16 Atrioventricular conduction; LIHC cis rs7959452 0.503 rs7300266 chr12:69654187 A/G cg20891283 chr12:69753455 YEATS4 0.73 13.35 0.59 5.11e-33 Blood protein levels; LIHC cis rs2576037 0.583 rs2156049 chr18:44455717 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.98 0.51 3.15e-24 Personality dimensions; LIHC cis rs6750795 0.569 rs1797387 chr2:232414692 A/G cg19187155 chr2:232395269 NMUR1 0.5 7.51 0.38 5.21e-13 Height; LIHC cis rs10464366 0.746 rs17171537 chr7:39145647 C/T cg10621924 chr7:39171070 POU6F2 0.43 6.7 0.34 8.71e-11 IgG glycosylation; LIHC cis rs56146971 0.763 rs75059313 chr14:91847559 T/A cg16433844 chr14:91963127 SMEK1 -0.56 -5.83 -0.3 1.25e-8 Alzheimer disease and age of onset; LIHC cis rs7107174 1.000 rs10899453 chr11:77997482 A/C cg02023728 chr11:77925099 USP35 0.51 9.66 0.46 1.08e-19 Testicular germ cell tumor; LIHC cis rs116248771 0.739 rs16829122 chr3:158312667 T/C cg16708174 chr3:158430962 RARRES1 0.48 6.29 0.32 9.6e-10 diarrhoeal disease at age 2; LIHC cis rs35110281 0.748 rs1584918 chr21:45042419 C/T cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.42e-23 Mean corpuscular volume; LIHC cis rs9814567 1.000 rs9864346 chr3:134312352 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -11.91 -0.54 1.31e-27 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10416265 0.527 rs6510337 chr19:33545701 C/T cg17764715 chr19:33622953 WDR88 0.53 7.13 0.36 6.01e-12 Bone properties (heel); LIHC cis rs11971779 0.680 rs111461944 chr7:139077903 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs240764 0.781 rs12212736 chr6:101151410 C/T cg09795085 chr6:101329169 ASCC3 -0.52 -7.14 -0.36 5.5e-12 Neuroticism; LIHC cis rs1355223 0.583 rs2941057 chr11:34882220 G/A cg11058730 chr11:34937778 PDHX;APIP 0.77 14.14 0.61 4.78e-36 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7572733 0.534 rs700692 chr2:198728500 T/C cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg12463550 chr7:65579703 CRCP 0.67 6.96 0.35 1.73e-11 Diabetic kidney disease; LIHC cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg06634786 chr22:41940651 POLR3H -0.82 -8.91 -0.43 3.12e-17 Vitiligo; LIHC trans rs1814175 0.562 rs1794130 chr11:49903764 T/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs585510 1 rs585510 chr12:121000133 A/G cg12219531 chr12:120966889 COQ5 0.68 13.61 0.59 5.27e-34 Reticulocyte fraction of red cells; LIHC cis rs2108622 0.727 rs2158511 chr19:15986647 C/T cg13772218 chr19:15982569 NA 0.36 7.5 0.38 5.71e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs7726839 0.540 rs3792720 chr5:643028 T/G cg09021430 chr5:549028 NA -0.41 -8.39 -0.41 1.33e-15 Obesity-related traits; LIHC cis rs7542091 0.813 rs2049999 chr1:210031331 A/G cg23283495 chr1:209979779 IRF6 0.36 5.97 0.31 5.79e-9 Monobrow; LIHC cis rs72634258 0.836 rs7545687 chr1:7997183 G/A cg00042356 chr1:8021962 PARK7 0.88 9.23 0.45 2.97e-18 Inflammatory bowel disease; LIHC trans rs208520 1.000 rs12216109 chr6:66987488 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.07 0.36 8.67e-12 Exhaled nitric oxide output; LIHC cis rs7940866 0.903 rs1433980 chr11:130870956 A/G cg12179176 chr11:130786555 SNX19 0.52 7.68 0.38 1.68e-13 Schizophrenia; LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg09455208 chr3:40491958 NA 0.41 8.21 0.41 4.71e-15 Renal cell carcinoma; LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg06420487 chr17:61919686 SMARCD2 0.45 6.02 0.31 4.5e-9 Height; LIHC cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg18357526 chr6:26021779 HIST1H4A 0.6 8.47 0.42 7.14e-16 Blood metabolite levels; LIHC cis rs11112613 0.713 rs12307351 chr12:105955634 T/A cg03607813 chr12:105948248 NA 0.62 11.95 0.54 9.32e-28 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7872515 0.536 rs10820938 chr9:94841980 C/T cg01248375 chr9:94877805 SPTLC1 0.56 6.63 0.34 1.33e-10 Bipolar disorder and schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13332130 chr19:41284234 RAB4B -0.49 -6.4 -0.33 5.1e-10 Systolic blood pressure; LIHC cis rs1577917 0.839 rs1596990 chr6:86550692 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.47 -0.37 6.61e-13 Response to antipsychotic treatment; LIHC cis rs8017423 0.967 rs11628812 chr14:90713720 G/T cg14092571 chr14:90743983 NA 0.39 6.22 0.32 1.45e-9 Mortality in heart failure; LIHC cis rs4888262 0.545 rs8050624 chr16:74686690 A/G cg01733217 chr16:74700730 RFWD3 -0.86 -17.65 -0.69 5.23e-50 Testicular germ cell tumor; LIHC cis rs7249142 0.597 rs7250650 chr19:19285989 A/T cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.27 -0.32 1.11e-9 IgG glycosylation; LIHC cis rs5758511 0.680 rs5758682 chr22:42645202 C/T cg20195005 chr22:42527684 CYP2D6 0.31 5.88 0.3 9.93e-9 Birth weight; LIHC cis rs9549367 1.000 rs9549367 chr13:113911532 C/G cg00898013 chr13:113819073 PROZ -0.35 -6.22 -0.32 1.47e-9 Platelet distribution width; LIHC cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg18404041 chr3:52824283 ITIH1 -0.51 -8.56 -0.42 3.8e-16 Bipolar disorder; LIHC cis rs9399135 0.967 rs11754783 chr6:135347661 T/A cg22676075 chr6:135203613 NA 0.39 6.32 0.32 8.12e-10 Red blood cell count; LIHC cis rs6815814 0.898 rs1873195 chr4:38891173 C/T cg06935464 chr4:38784597 TLR10 0.44 6.61 0.34 1.49e-10 Breast cancer; LIHC cis rs9300255 0.596 rs11057202 chr12:123720775 G/T cg00376283 chr12:123451042 ABCB9 0.69 10.45 0.49 2.36e-22 Neutrophil percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14257814 chr17:30470253 RHOT1 0.47 6.04 0.31 3.94e-9 Lung function (FEV1/FVC); LIHC cis rs7208859 0.623 rs58908911 chr17:29244558 C/T cg13385521 chr17:29058706 SUZ12P 0.81 7.95 0.4 2.66e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg27438040 chr6:136611664 BCLAF1 -0.44 -6.41 -0.33 4.88e-10 Eotaxin levels; LIHC trans rs3960554 0.673 rs112680895 chr7:75623520 G/A cg19862616 chr7:65841803 NCRNA00174 0.56 7.59 0.38 3.08e-13 Eotaxin levels; LIHC cis rs9309473 1.000 rs6546835 chr2:73664715 G/A cg20560298 chr2:73613845 ALMS1 -0.56 -7.05 -0.36 9.96e-12 Metabolite levels; LIHC cis rs2710642 0.564 rs7583570 chr2:62852926 C/T cg17519650 chr2:63277830 OTX1 0.43 6.89 0.35 2.65e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs2033908 0.558 rs6486064 chr11:12869509 T/C cg25843174 chr11:12811716 TEAD1 -0.31 -7.11 -0.36 6.71e-12 Sitting height ratio; LIHC cis rs17253792 0.822 rs10142757 chr14:56074211 C/A cg01858014 chr14:56050164 KTN1 -0.78 -8.27 -0.41 3.09e-15 Putamen volume; LIHC trans rs2727020 0.556 rs2866365 chr11:49390731 A/G cg15704280 chr7:45808275 SEPT13 -0.77 -11.23 -0.52 3.94e-25 Coronary artery disease; LIHC cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg23205692 chr1:25664452 TMEM50A 0.36 5.8 0.3 1.5e-8 Erythrocyte sedimentation rate; LIHC cis rs9921222 0.597 rs3848369 chr16:415078 C/T cg08923669 chr16:420230 MRPL28 -0.43 -6.17 -0.32 1.94e-9 Bone mineral density (spine);Bone mineral density; LIHC trans rs1814175 0.717 rs11040450 chr11:49650638 G/A cg03929089 chr4:120376271 NA -0.88 -16.9 -0.67 5.32e-47 Height; LIHC cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC trans rs8073060 0.505 rs225270 chr17:33968871 A/T cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24973585 chr14:103851607 MARK3 -0.43 -6.13 -0.31 2.48e-9 Pancreatic cancer; LIHC cis rs34779708 0.931 rs2384287 chr10:35340559 A/G cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.49e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1580019 0.844 rs1037322 chr7:32501857 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.99 16.98 0.68 2.52e-47 Cognitive ability; LIHC trans rs7618501 0.521 rs952594 chr3:49908023 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.67 0.34 1.06e-10 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.706 rs12950186 chr17:37393395 A/C cg07936489 chr17:37558343 FBXL20 -0.78 -11.2 -0.52 5.15e-25 Glomerular filtration rate (creatinine); LIHC cis rs3736594 0.765 rs12994085 chr2:27952406 C/T cg27432699 chr2:27873401 GPN1 -0.46 -7.08 -0.36 8.29e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs67311347 1.000 rs2887995 chr3:40409029 C/G cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.46e-9 Renal cell carcinoma; LIHC cis rs11229555 0.645 rs11229457 chr11:58207203 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs713477 1.000 rs8014621 chr14:55906849 A/C cg13175173 chr14:55914753 NA -0.32 -6.99 -0.35 1.45e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs2463822 1.000 rs2513076 chr11:62103711 A/G cg06239285 chr11:62104954 ASRGL1 0.92 6.89 0.35 2.76e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs6912958 0.512 rs910563 chr6:88058885 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.35 0.37 1.48e-12 Monocyte percentage of white cells; LIHC cis rs17685 0.753 rs10245584 chr7:75745866 C/T cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs66887589 0.660 rs4833613 chr4:120150156 A/C cg09307838 chr4:120376055 NA -0.42 -6.28 -0.32 1.03e-9 Diastolic blood pressure; LIHC cis rs9911578 1.000 rs3744109 chr17:56594197 C/T cg05425664 chr17:57184151 TRIM37 0.58 8.51 0.42 5.54e-16 Intelligence (multi-trait analysis); LIHC cis rs7116495 0.609 rs567851 chr11:71592419 G/C cg26138937 chr11:71823887 C11orf51 1.04 8.4 0.41 1.17e-15 Severe influenza A (H1N1) infection; LIHC cis rs9649465 0.934 rs718781 chr7:123313573 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.08 -0.4 1.09e-14 Migraine; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T ch.7.38331565R chr7:38365040 NA -0.5 -6.5 -0.33 2.79e-10 Hepatitis; LIHC cis rs2073300 0.609 rs77673953 chr20:23398794 G/C cg12062639 chr20:23401060 NAPB 1.05 14.07 0.61 8.82e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs17253792 0.822 rs10137885 chr14:56173590 A/G cg01858014 chr14:56050164 KTN1 -0.64 -7.01 -0.35 1.29e-11 Putamen volume; LIHC cis rs2549003 1.000 rs2549003 chr5:131829297 A/G cg21138405 chr5:131827807 IRF1 0.36 9.43 0.45 6.41e-19 Asthma (sex interaction); LIHC cis rs2204008 0.840 rs3892363 chr12:38479487 G/A cg26384229 chr12:38710491 ALG10B 0.69 9.62 0.46 1.47e-19 Bladder cancer; LIHC cis rs28374715 0.681 rs8037574 chr15:41630770 T/C cg18705301 chr15:41695430 NDUFAF1 -0.98 -13.57 -0.59 7.14e-34 Ulcerative colitis; LIHC cis rs4665809 1.000 rs4665821 chr2:26309949 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.72 -9.02 -0.44 1.34e-17 Gut microbiome composition (summer); LIHC cis rs614226 1.000 rs1167726 chr12:120967364 A/C cg01236616 chr12:121019343 POP5 -1.22 -19.21 -0.72 2.69e-56 Type 1 diabetes nephropathy; LIHC cis rs12291225 0.679 rs11369 chr11:14288096 A/G cg05501817 chr11:14380813 RRAS2 -0.43 -5.87 -0.3 1.03e-8 Sense of smell; LIHC cis rs3812111 0.586 rs7763110 chr6:116456335 G/A cg08036074 chr6:116424633 NT5DC1 -0.5 -8.57 -0.42 3.7e-16 Age-related macular degeneration; LIHC cis rs9914988 0.943 rs12951232 chr17:27132638 G/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.86 -0.35 3.23e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs9733 0.596 rs72702580 chr1:150691285 A/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs950169 1.000 rs35648189 chr15:84740748 T/C cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs1559088 1.000 rs7245404 chr19:33550589 C/T cg17764715 chr19:33622953 WDR88 0.4 5.72 0.3 2.29e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs35110281 0.720 rs162392 chr21:44941406 A/G cg01579765 chr21:45077557 HSF2BP -0.34 -6.18 -0.32 1.87e-9 Mean corpuscular volume; LIHC cis rs8062405 0.625 rs8060365 chr16:28911309 C/A cg00204512 chr16:28754710 NA -0.38 -6.51 -0.33 2.71e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs897984 0.644 rs73524556 chr16:30823162 G/A cg02466173 chr16:30829666 NA -0.44 -7.52 -0.38 4.91e-13 Dementia with Lewy bodies; LIHC cis rs769267 1.000 rs2074089 chr19:19449603 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -9.83 -0.47 3.04e-20 Tonsillectomy; LIHC cis rs6504950 0.800 rs9916547 chr17:53006890 G/A cg10237252 chr17:52977213 TOM1L1 -0.34 -5.99 -0.31 5.22e-9 Breast cancer; LIHC cis rs875971 0.862 rs778684 chr7:65836403 A/T cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs7027203 0.797 rs3996254 chr9:96591239 A/G cg14598338 chr9:96623480 NA -0.33 -6.57 -0.33 1.9e-10 DNA methylation (variation); LIHC cis rs7296418 0.675 rs1879379 chr12:123727443 G/A cg00376283 chr12:123451042 ABCB9 0.64 10.53 0.49 1.19e-22 Platelet count; LIHC cis rs10792665 0.844 rs7125791 chr11:82680505 G/A cg24227371 chr11:82718527 RAB30 -0.31 -7.51 -0.38 5.14e-13 Obesity-related traits; LIHC cis rs8067354 0.540 rs1051424 chr17:58024324 A/G cg13753209 chr17:57696993 CLTC 0.72 10.55 0.5 1.02e-22 Hemoglobin concentration; LIHC cis rs2559856 1.000 rs2559858 chr12:102089300 A/G cg12924262 chr12:102091054 CHPT1 0.53 8.57 0.42 3.54e-16 Blood protein levels; LIHC cis rs67311347 1.000 rs11129876 chr3:40401636 C/T cg09455208 chr3:40491958 NA -0.35 -7.2 -0.36 3.82e-12 Renal cell carcinoma; LIHC cis rs2412488 0.962 rs1531748 chr4:54265333 A/G cg22241045 chr4:54363911 LNX1 -0.47 -7.52 -0.38 4.91e-13 DNA methylation (variation); LIHC cis rs12594515 0.967 rs11070466 chr15:45984955 C/T cg19682013 chr15:45996608 NA 0.4 7.12 0.36 6.25e-12 Waist circumference;Weight; LIHC cis rs11098699 0.948 rs4833888 chr4:124208497 G/T cg09941581 chr4:124220074 SPATA5 -0.32 -5.77 -0.3 1.75e-8 Mosquito bite size; LIHC cis rs2108622 1.000 rs55744319 chr19:15981821 G/A cg13772218 chr19:15982569 NA 0.42 8.58 0.42 3.34e-16 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.74 -13.89 -0.6 4.2e-35 Prudent dietary pattern; LIHC cis rs765787 0.530 rs11854294 chr15:45527996 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.05e-13 Uric acid levels; LIHC trans rs1814175 0.645 rs28627251 chr11:50048125 G/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs77633900 0.772 rs78181637 chr15:76672569 A/C cg21673338 chr15:77095150 SCAPER -0.52 -5.96 -0.31 6.26e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs875971 0.862 rs6460306 chr7:66060793 T/C cg18252515 chr7:66147081 NA 0.45 6.57 0.33 1.87e-10 Aortic root size; LIHC cis rs35110281 0.633 rs2329593 chr21:45121987 T/C cg04455712 chr21:45112962 RRP1B 0.49 8.43 0.41 9.57e-16 Mean corpuscular volume; LIHC cis rs11864453 0.713 rs2241412 chr16:72144284 A/G cg01557791 chr16:72042693 DHODH -0.46 -7.63 -0.38 2.42e-13 Fibrinogen levels; LIHC cis rs12971120 0.685 rs34780792 chr18:72173278 G/A cg25817165 chr18:72167213 CNDP2 -0.69 -11.88 -0.54 1.68e-27 Refractive error; LIHC cis rs317689 0.819 rs317667 chr12:69703754 G/T cg14784868 chr12:69753453 YEATS4 0.6 8.81 0.43 6.54e-17 Response to diuretic therapy; LIHC cis rs2777491 0.915 rs28583065 chr15:41608470 T/C cg18705301 chr15:41695430 NDUFAF1 -0.56 -8.28 -0.41 2.89e-15 Ulcerative colitis; LIHC cis rs10791323 0.536 rs4937842 chr11:133734542 C/G cg06766960 chr11:133703094 NA 0.56 9.25 0.45 2.4e-18 Childhood ear infection; LIHC cis rs4650994 0.593 rs12074085 chr1:178504163 G/A cg05350800 chr1:178550844 NA -0.3 -6.42 -0.33 4.65e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg27286337 chr10:134555280 INPP5A 0.88 13.16 0.58 2.8099999999999997e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12701220 0.520 rs7803208 chr7:1162084 C/T cg23978390 chr7:1156363 C7orf50 0.68 10.01 0.48 7.67e-21 Bronchopulmonary dysplasia; LIHC trans rs35110281 0.837 rs2838342 chr21:45077865 G/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.41 0.33 4.71e-10 Mean corpuscular volume; LIHC cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Bipolar disorder; LIHC cis rs1775715 0.737 rs2799018 chr10:32202069 C/T cg14930904 chr10:32216787 ARHGAP12 0.34 5.98 0.31 5.74e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs1506636 1.000 rs60689684 chr7:123370403 C/T cg03229431 chr7:123269106 ASB15 0.62 12.47 0.56 1.11e-29 Plateletcrit;Platelet count; LIHC cis rs72781680 0.898 rs718139 chr2:23975911 G/A cg08917208 chr2:24149416 ATAD2B 0.93 7.85 0.39 5.27e-14 Lymphocyte counts; LIHC cis rs6545883 0.894 rs2694649 chr2:61573826 G/A cg14146966 chr2:61757674 XPO1 -0.44 -7.46 -0.37 7.39e-13 Tuberculosis; LIHC cis rs908922 0.676 rs1001834 chr1:152495940 C/A cg20991723 chr1:152506922 NA 0.59 10.49 0.49 1.6400000000000001e-22 Hair morphology; LIHC cis rs477692 0.905 rs555545 chr10:131411586 G/A cg05714579 chr10:131428358 MGMT 0.5 8.5 0.42 5.78e-16 Response to temozolomide; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21153962 chr11:57102758 SSRP1 0.45 6.53 0.33 2.44e-10 Lung function (FEV1/FVC); LIHC cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg12310025 chr6:25882481 NA -0.64 -9.01 -0.44 1.54e-17 Blood metabolite levels; LIHC cis rs1577917 0.917 rs35038582 chr6:86721305 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.44e-11 Response to antipsychotic treatment; LIHC cis rs10876993 0.749 rs703832 chr12:58024626 G/C cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.07 -0.31 3.41e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs3812831 0.695 rs6560936 chr13:114945972 C/T cg08824895 chr13:115047677 UPF3A -0.48 -6.92 -0.35 2.28e-11 Schizophrenia; LIHC cis rs7659604 0.502 rs13128434 chr4:122672461 A/C cg19671926 chr4:122722719 EXOSC9 0.5 7.37 0.37 1.26e-12 Type 2 diabetes; LIHC cis rs7818688 0.697 rs60003497 chr8:95983423 A/T cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs11690935 0.885 rs10202823 chr2:172780132 T/C cg13550731 chr2:172543902 DYNC1I2 -0.8 -14.4 -0.61 4.4e-37 Schizophrenia; LIHC cis rs2153535 0.580 rs9379215 chr6:8481225 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs7192750 0.586 rs62053803 chr16:71989413 G/A cg06353428 chr16:71660113 MARVELD3 0.78 9.09 0.44 8.46e-18 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC cis rs2455799 0.593 rs2470544 chr3:15727234 A/G cg12698662 chr3:15914712 MIR563 -0.37 -6.72 -0.34 7.42e-11 Mean platelet volume; LIHC cis rs244293 0.965 rs244368 chr17:53186537 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.47 -0.37 6.93e-13 Menarche (age at onset); LIHC cis rs9296095 0.747 rs12206050 chr6:33564296 A/T cg14003231 chr6:33640908 ITPR3 0.3 5.85 0.3 1.14e-8 Platelet count; LIHC cis rs72843506 0.656 rs80250684 chr17:19958296 C/T cg12065943 chr17:19881925 AKAP10 -0.33 -6.01 -0.31 4.71e-9 Schizophrenia; LIHC cis rs5758659 0.714 rs5758578 chr22:42490292 A/C cg19513890 chr22:42538836 CYP2D7P1 0.41 8.09 0.4 1.02e-14 Cognitive function; LIHC cis rs9443645 0.901 rs56057971 chr6:79607182 G/A cg05283184 chr6:79620031 NA -0.33 -5.73 -0.3 2.15e-8 Intelligence (multi-trait analysis); LIHC cis rs9918079 0.560 rs7662032 chr4:15635414 C/G cg21123203 chr4:15471301 CC2D2A -0.45 -7.3 -0.37 2.04e-12 Obesity-related traits; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11057824 chr14:50471938 C14orf182 0.42 6.82 0.35 4.2e-11 Cognitive function; LIHC cis rs3096299 0.967 rs2911257 chr16:89484134 C/G cg08822215 chr16:89438651 ANKRD11 -0.5 -7.96 -0.4 2.57e-14 Multiple myeloma (IgH translocation); LIHC cis rs951366 0.903 rs708723 chr1:205739266 C/T cg14159672 chr1:205819179 PM20D1 0.33 5.83 0.3 1.28e-8 Menarche (age at onset); LIHC cis rs9457247 0.967 rs447042 chr6:167405435 C/T cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC cis rs2732480 0.538 rs1387260 chr12:48703091 A/C cg21466736 chr12:48725269 NA -0.71 -10.78 -0.5 1.62e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg17554472 chr22:41940697 POLR3H -0.53 -5.89 -0.3 9.25e-9 Vitiligo; LIHC cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.47 0.49 1.98e-22 Vitiligo; LIHC cis rs8084351 0.577 rs4444405 chr18:50621027 C/A cg24270629 chr18:50823537 DCC 0.44 6.66 0.34 1.07e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs3806843 0.733 rs801181 chr5:140092814 C/T cg16179182 chr5:140090404 VTRNA1-1 0.35 5.8 0.3 1.53e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2073499 1.000 rs57319506 chr3:50285677 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.63 6.48 0.33 3.11e-10 Schizophrenia; LIHC cis rs7408868 0.908 rs45591935 chr19:15277006 T/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.77 -0.3 1.79e-8 Pulse pressure; LIHC cis rs4820294 0.669 rs1894532 chr22:38059750 T/C cg10587741 chr22:38071170 LGALS1 0.43 7.56 0.38 3.77e-13 Fat distribution (HIV); LIHC cis rs7613875 0.620 rs7634441 chr3:50071677 G/A cg24110177 chr3:50126178 RBM5 0.55 8.89 0.43 3.56e-17 Body mass index; LIHC cis rs208520 0.690 rs207112 chr6:66792092 C/T cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC cis rs1707322 0.963 rs12145287 chr1:46325002 C/G cg06784218 chr1:46089804 CCDC17 0.38 6.63 0.34 1.33e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6545883 0.965 rs9989775 chr2:61761774 A/G cg14146966 chr2:61757674 XPO1 0.47 8.21 0.41 4.61e-15 Tuberculosis; LIHC cis rs17539620 0.506 rs62432749 chr6:154839219 G/A cg17771515 chr6:154831774 CNKSR3 0.56 5.91 0.3 8.35e-9 Lipoprotein (a) levels; LIHC cis rs7100689 0.784 rs10736341 chr10:82061206 C/G cg01528321 chr10:82214614 TSPAN14 0.87 11.96 0.54 8.55e-28 Post bronchodilator FEV1; LIHC cis rs7937890 1.000 rs2970334 chr11:14329355 C/T cg23387056 chr11:14280742 SPON1 0.43 5.99 0.31 5.25e-9 Mitochondrial DNA levels; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg09033563 chr22:24373618 LOC391322 -0.48 -6.61 -0.34 1.46e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9660992 0.736 rs1180734 chr1:205255438 A/G cg21545522 chr1:205238299 TMCC2 0.31 6.37 0.33 6.11e-10 Mean corpuscular volume;Mean platelet volume; LIHC cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg23982607 chr1:1823379 GNB1 -0.44 -7.32 -0.37 1.78e-12 Body mass index; LIHC cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.69 -11.75 -0.54 5.38e-27 Menarche (age at onset); LIHC cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.22e-8 Menopause (age at onset); LIHC cis rs6831352 0.918 rs13112733 chr4:100050319 A/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs9916302 0.706 rs2879259 chr17:37410892 C/G cg07936489 chr17:37558343 FBXL20 -0.85 -12.52 -0.56 7.52e-30 Glomerular filtration rate (creatinine); LIHC cis rs7903847 0.642 rs7903562 chr10:99154782 T/C cg08345082 chr10:99160200 RRP12 -0.39 -6.62 -0.34 1.38e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9549328 0.527 rs9549622 chr13:113640064 A/C cg14765414 chr13:113652335 MCF2L -0.39 -6.47 -0.33 3.3e-10 Systolic blood pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07798295 chr16:89715839 CHMP1A -0.44 -6.34 -0.32 7.48e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9399137 0.507 rs12664898 chr6:135288663 T/C cg24558204 chr6:135376177 HBS1L 0.62 10.46 0.49 2.04e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs55823223 0.564 rs12103594 chr17:73855279 C/T cg08125733 chr17:73851984 WBP2 0.88 12.41 0.56 1.83e-29 Psoriasis; LIHC cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg13126279 chr21:47581558 C21orf56 -0.46 -7.54 -0.38 4.18e-13 Testicular germ cell tumor; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00699235 chr12:49962218 MCRS1 0.45 6.3 0.32 9.36e-10 Pancreatic cancer; LIHC cis rs9326248 0.817 rs1242127 chr11:117076564 A/G cg26566898 chr11:117069891 TAGLN -0.46 -7.39 -0.37 1.17e-12 Blood protein levels; LIHC trans rs7193541 0.684 rs9929496 chr16:74668473 G/A cg23598604 chr1:99732472 LPPR4 -0.29 -6.06 -0.31 3.63e-9 Multiple myeloma; LIHC cis rs7843479 0.582 rs11779655 chr8:21794041 A/G cg17168535 chr8:21777572 XPO7 -0.62 -11.66 -0.53 1.13e-26 Mean corpuscular volume; LIHC cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg05025164 chr4:1340916 KIAA1530 0.57 9.16 0.44 4.89e-18 Obesity-related traits; LIHC trans rs10761482 0.566 rs10159663 chr10:62208417 A/G cg17314160 chr12:110399253 GIT2 0.41 6.27 0.32 1.11e-9 Schizophrenia; LIHC cis rs10078 0.515 rs2672739 chr5:443447 A/C cg24955955 chr5:415729 AHRR 0.6 10.94 0.51 4.3e-24 Fat distribution (HIV); LIHC cis rs9942416 0.601 rs40059 chr5:74964582 A/G cg00601450 chr5:74908170 NA -0.45 -6.55 -0.33 2.16e-10 Age-related disease endophenotypes; LIHC cis rs67311347 1.000 rs9842564 chr3:40405810 A/G cg09455208 chr3:40491958 NA -0.31 -6.32 -0.32 8.08e-10 Renal cell carcinoma; LIHC cis rs7618501 1.000 rs7618501 chr3:49772647 A/G cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs6783573 0.895 rs1049667 chr3:46623690 C/A cg21489266 chr3:46619131 LRRC2;TDGF1 -0.41 -6.48 -0.33 3.27e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs250677 0.687 rs2963484 chr5:148451127 A/T cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.93e-9 Breast cancer; LIHC cis rs8103278 0.864 rs2070737 chr19:46282890 A/T cg02376097 chr19:46275166 DMPK -0.46 -7.19 -0.36 4.21e-12 Coronary artery disease; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg20756454 chr17:28951397 LRRC37B2 0.39 6.4 0.33 5.06e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs708547 0.647 rs1403233 chr4:57885053 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.46 -6.61 -0.34 1.45e-10 Response to bleomycin (chromatid breaks); LIHC cis rs7927592 0.913 rs4084149 chr11:68288567 A/G cg16797656 chr11:68205561 LRP5 0.52 8.27 0.41 2.96e-15 Total body bone mineral density; LIHC cis rs10174077 0.687 rs4664491 chr2:152479986 C/T cg19508488 chr2:152266495 RIF1 0.51 7.0 0.35 1.39e-11 Squamous cell lung carcinoma; LIHC cis rs796364 0.625 rs1369843 chr2:201088171 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.51 6.0 0.31 5.05e-9 Schizophrenia; LIHC cis rs66573146 0.831 rs67315413 chr4:6987910 T/C cg15105060 chr4:7024189 TBC1D14 -0.75 -6.63 -0.34 1.3100000000000001e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg16970926 chr12:29381810 FAR2 0.33 6.93 0.35 2.1e-11 QT interval; LIHC cis rs7131987 0.650 rs7301188 chr12:29455391 C/T cg00204748 chr12:29376779 FAR2 0.38 7.0 0.35 1.36e-11 QT interval; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.76e-9 Menopause (age at onset); LIHC cis rs7546668 1.000 rs4233533 chr1:15829187 G/A cg11706911 chr1:15910989 AGMAT 0.44 6.67 0.34 1.04e-10 Glomerular filtration rate (creatinine); LIHC cis rs116095464 0.558 rs28636067 chr5:199415 G/A cg22496380 chr5:211416 CCDC127 -1.18 -10.26 -0.49 1.01e-21 Breast cancer; LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC cis rs8081395 0.836 rs2150879 chr17:57859210 G/A cg13753209 chr17:57696993 CLTC -0.46 -7.15 -0.36 5.43e-12 White blood cell count; LIHC cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg08645402 chr16:4508243 NA 0.42 7.79 0.39 8.17e-14 Schizophrenia; LIHC cis rs2797160 1.000 rs6904069 chr6:125995134 C/T cg05901451 chr6:126070800 HEY2 -0.4 -6.7 -0.34 8.7e-11 Endometrial cancer; LIHC cis rs4474465 0.646 rs10793335 chr11:78279005 C/G cg27205649 chr11:78285834 NARS2 0.5 7.82 0.39 6.79e-14 Alzheimer's disease (survival time); LIHC cis rs11190604 0.943 rs11190574 chr10:102234331 T/C cg07080220 chr10:102295463 HIF1AN 0.5 6.99 0.35 1.48e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03670153 chr3:184079754 CLCN2;POLR2H 0.46 6.61 0.34 1.51e-10 Pancreatic cancer; LIHC cis rs1775715 0.707 rs2065443 chr10:32164236 C/G cg14930904 chr10:32216787 ARHGAP12 0.36 6.22 0.32 1.42e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg16434002 chr17:42200994 HDAC5 -0.53 -7.71 -0.38 1.4e-13 Total body bone mineral density; LIHC cis rs10207060 0.500 rs2118399 chr2:240683795 T/C cg07506560 chr2:240697449 NA 0.39 5.76 0.3 1.84e-8 Obesity-related traits; LIHC cis rs2637266 0.967 rs2579760 chr10:78321768 A/C cg18941641 chr10:78392320 NA 0.28 5.97 0.31 5.87e-9 Pulmonary function; LIHC cis rs10493773 0.609 rs11161660 chr1:86184066 C/T cg17807903 chr1:86174739 ZNHIT6 -0.61 -11.91 -0.54 1.33e-27 Urate levels in overweight individuals; LIHC cis rs28830936 1.000 rs11637341 chr15:41955825 G/T cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.74 -0.3 2.07e-8 Diastolic blood pressure; LIHC cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg22618164 chr12:122356400 WDR66 0.63 11.08 0.51 1.43e-24 Mean corpuscular volume; LIHC cis rs11711311 1.000 rs2242108 chr3:113433903 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.06 -0.36 9.32e-12 IgG glycosylation; LIHC cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg23978390 chr7:1156363 C7orf50 0.51 7.61 0.38 2.77e-13 Longevity;Endometriosis; LIHC cis rs4665809 0.878 rs6720312 chr2:26364934 A/G cg26119090 chr2:26468346 HADHA;HADHB 0.79 10.03 0.48 6.26e-21 Gut microbiome composition (summer); LIHC cis rs17433710 0.516 rs4411113 chr1:162668008 G/T cg01063088 chr1:162760584 HSD17B7 0.44 6.32 0.32 8.32e-10 Dupuytren's disease; LIHC cis rs425535 0.588 rs13136948 chr4:74806194 A/T cg02530824 chr4:74847766 PF4 -0.39 -5.98 -0.31 5.65e-9 Blood protein levels; LIHC cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg23758822 chr17:41437982 NA 0.9 16.66 0.67 4.63e-46 Menopause (age at onset); LIHC cis rs16828019 0.777 rs11209363 chr1:41485077 T/C cg03962019 chr1:41807865 NA 0.5 7.09 0.36 7.76e-12 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.954 rs10034623 chr4:120397829 G/A cg09307838 chr4:120376055 NA 0.77 12.55 0.56 5.52e-30 Corneal astigmatism; LIHC cis rs4654899 0.965 rs61781115 chr1:21322860 C/T cg08539965 chr1:21396338 EIF4G3 0.34 5.86 0.3 1.09e-8 Superior frontal gyrus grey matter volume; LIHC cis rs10464366 0.746 rs17171537 chr7:39145647 C/T cg18850127 chr7:39170497 POU6F2 0.49 8.67 0.42 1.72e-16 IgG glycosylation; LIHC cis rs7772486 0.686 rs1292334 chr6:145968288 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.95 -0.31 6.51e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs34779708 0.733 rs7070778 chr10:35541688 T/C cg03585969 chr10:35415529 CREM 0.76 10.83 0.51 1.05e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2303759 0.676 rs7248378 chr19:49908144 C/A cg22307029 chr19:49891270 CCDC155 0.58 9.33 0.45 1.41e-18 Multiple sclerosis; LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg03366896 chr10:135186866 ECHS1 0.42 6.25 0.32 1.24e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs769267 0.930 rs1865034 chr19:19605763 C/T cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.99 0.31 5.2e-9 Tonsillectomy; LIHC cis rs9309473 0.579 rs6728128 chr2:73595982 T/C cg20560298 chr2:73613845 ALMS1 -0.45 -7.16 -0.36 5.13e-12 Metabolite levels; LIHC cis rs243505 0.660 rs3807451 chr7:148538622 T/C cg09806900 chr7:148480153 CUL1 0.44 6.22 0.32 1.44e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 0.862 rs35378740 chr7:65987712 C/A cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.38e-11 Aortic root size; LIHC cis rs4819052 0.851 rs35871601 chr21:46675214 C/T cg22633049 chr21:46681294 NA -0.36 -6.29 -0.32 9.93e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs17376456 0.877 rs12374463 chr5:93483569 C/G cg25358565 chr5:93447407 FAM172A 1.12 10.26 0.49 1.06e-21 Diabetic retinopathy; LIHC cis rs9649465 1.000 rs10215473 chr7:123380681 C/G cg03229431 chr7:123269106 ASB15 -0.37 -8.04 -0.4 1.53e-14 Migraine; LIHC cis rs6840360 1.000 rs6535814 chr4:152609694 A/G cg22705602 chr4:152727874 NA -0.31 -6.62 -0.34 1.39e-10 Intelligence (multi-trait analysis); LIHC cis rs9818758 0.607 rs9311439 chr3:49310408 A/G cg06212747 chr3:49208901 KLHDC8B -0.68 -5.95 -0.31 6.67e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2576037 0.526 rs571181 chr18:44376399 T/C cg19077165 chr18:44547161 KATNAL2 -0.39 -5.97 -0.31 5.93e-9 Personality dimensions; LIHC cis rs2540917 0.631 rs11884411 chr2:60669494 C/T cg00543073 chr2:60773386 BCL11A 0.3 5.88 0.3 9.88e-9 Mean corpuscular volume; LIHC cis rs10876993 0.749 rs703832 chr12:58024626 G/C cg18357645 chr12:58087776 OS9 0.49 7.67 0.38 1.79e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg04013166 chr16:89971882 TCF25 0.61 8.01 0.4 1.87e-14 Skin colour saturation; LIHC cis rs950169 0.960 rs35159785 chr15:84804014 G/A cg03959625 chr15:84868606 LOC388152 0.46 5.75 0.3 1.99e-8 Schizophrenia; LIHC cis rs4919087 0.962 rs10748694 chr10:99056190 A/T cg25902810 chr10:99078978 FRAT1 0.7 10.37 0.49 4.26e-22 Monocyte count; LIHC trans rs10411161 0.702 rs11878586 chr19:52388576 A/G cg22319618 chr22:45562946 NUP50 -0.62 -8.49 -0.42 6.32e-16 Breast cancer; LIHC cis rs7131987 0.683 rs3782511 chr12:29496224 G/A cg12903224 chr12:29470962 FAR2 -0.41 -6.56 -0.33 1.99e-10 QT interval; LIHC cis rs600806 0.778 rs9661614 chr1:110021837 T/C cg08911820 chr1:110026001 ATXN7L2 0.53 6.61 0.34 1.5e-10 Intelligence (multi-trait analysis); LIHC cis rs61542988 0.570 rs62448268 chr7:22829464 G/A cg11367502 chr7:22862612 TOMM7 0.56 9.07 0.44 9.4e-18 Fibrinogen levels; LIHC cis rs861318 0.702 rs2814771 chr1:159012238 A/G cg11003133 chr1:159046391 AIM2 0.32 6.63 0.34 1.3100000000000001e-10 Obesity-related traits; LIHC cis rs4891159 0.756 rs3892540 chr18:74118058 C/T cg24786174 chr18:74118243 ZNF516 -0.78 -14.04 -0.6 1.09e-35 Longevity; LIHC trans rs875971 0.508 rs6947808 chr7:66045082 A/G cg26939375 chr7:64535504 NA -0.44 -7.45 -0.37 7.9e-13 Aortic root size; LIHC cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs2243480 1.000 rs4718316 chr7:65648731 A/G cg10756647 chr7:56101905 PSPH -1.07 -13.17 -0.58 2.44e-32 Diabetic kidney disease; LIHC cis rs6121246 0.567 rs6060260 chr20:30192907 C/T cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03065641 chr8:145133200 EXOSC4 0.4 6.29 0.32 9.72e-10 Cognitive function; LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.97 -0.31 5.99e-9 Total body bone mineral density; LIHC trans rs637571 0.510 rs12575663 chr11:65574535 G/A cg17712092 chr4:129076599 LARP1B -0.7 -10.23 -0.48 1.32e-21 Eosinophil percentage of white cells; LIHC cis rs651907 0.535 rs34161138 chr3:101510388 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC trans rs1347297 0.526 rs919177 chr2:179258923 C/T cg14011486 chr1:26737247 LIN28 0.52 7.87 0.39 4.8e-14 Alzheimer disease and age of onset; LIHC cis rs986417 0.711 rs761556 chr14:61061034 T/G cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs2380220 0.872 rs2613528 chr6:95939437 C/G cg04719120 chr6:96025338 MANEA -0.56 -5.88 -0.3 9.69e-9 Behavioural disinhibition (generation interaction); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00021237 chr8:67525849 MYBL1 -0.32 -6.33 -0.32 7.89e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs116095464 0.558 rs1812843 chr5:267658 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.12 0.36 6.4e-12 Breast cancer; LIHC cis rs1185460 0.967 rs1177563 chr11:118949083 C/T cg23280166 chr11:118938394 VPS11 0.55 7.17 0.36 4.74e-12 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26376749 chr17:30677620 ZNF207 0.48 6.65 0.34 1.13e-10 Pancreatic cancer; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.85 -0.3 1.16e-8 Total body bone mineral density; LIHC cis rs6933660 0.745 rs3800272 chr6:151744283 A/G cg14262678 chr6:151773367 RMND1;C6orf211 -0.44 -6.41 -0.33 4.71e-10 Menarche (age at onset); LIHC cis rs7954584 0.520 rs1169095 chr12:122465738 G/A cg21171335 chr12:122356390 WDR66 -0.42 -6.81 -0.35 4.37e-11 Mean corpuscular volume; LIHC cis rs801193 1.000 rs4717310 chr7:66161007 C/T cg18876405 chr7:65276391 NA 0.43 7.57 0.38 3.61e-13 Aortic root size; LIHC trans rs7618501 1.000 rs3749240 chr3:49750188 T/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC cis rs79839061 0.656 rs11726508 chr4:888937 C/T cg07828340 chr4:882639 GAK 0.54 5.75 0.3 2.01e-8 Intelligence (multi-trait analysis); LIHC cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg13271783 chr10:134563150 INPP5A -0.6 -7.18 -0.36 4.32e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3741151 1.000 rs79778136 chr11:73041339 T/C cg17517138 chr11:73019481 ARHGEF17 0.92 6.82 0.35 4.21e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs80282103 0.867 rs13377037 chr10:1068639 C/T cg20335179 chr10:1068567 C10orf110;IDI2 -0.61 -6.92 -0.35 2.23e-11 Glomerular filtration rate (creatinine); LIHC cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg03517284 chr6:25882590 NA -0.63 -9.01 -0.44 1.44e-17 Blood metabolite levels; LIHC cis rs1707322 0.682 rs12037459 chr1:46094959 T/G cg24296786 chr1:45957014 TESK2 -0.41 -5.94 -0.31 6.87e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1403694 0.695 rs11927941 chr3:186433046 A/G cg12454167 chr3:186435060 KNG1 0.4 9.11 0.44 7.3e-18 Blood protein levels; LIHC cis rs1030877 1.000 rs2254301 chr2:105880734 G/A cg02079111 chr2:105885981 TGFBRAP1 0.68 11.83 0.54 2.67e-27 Obesity-related traits; LIHC cis rs35110281 0.627 rs7282704 chr21:44966253 A/G cg21573476 chr21:45109991 RRP1B -0.52 -9.78 -0.47 4.43e-20 Mean corpuscular volume; LIHC cis rs3796352 1.000 rs3796352 chr3:52913279 C/T cg04865290 chr3:52927548 TMEM110 -0.55 -6.17 -0.32 1.89e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs1048238 0.506 rs698890 chr1:16267371 C/G cg00529422 chr1:16285251 ZBTB17 0.33 6.3 0.32 9.39e-10 Systolic blood pressure; LIHC cis rs8017423 0.967 rs4900033 chr14:90701963 C/A cg04374321 chr14:90722782 PSMC1 0.74 14.42 0.61 3.67e-37 Mortality in heart failure; LIHC cis rs7677751 0.806 rs4864861 chr4:55097685 C/T cg17187183 chr4:55093834 PDGFRA 0.67 8.4 0.41 1.21e-15 Corneal astigmatism; LIHC trans rs7618501 0.966 rs2246832 chr3:49881134 A/T cg21582582 chr3:182698605 DCUN1D1 0.54 6.92 0.35 2.31e-11 Intelligence (multi-trait analysis); LIHC cis rs3020736 0.500 rs5996111 chr22:42493902 C/T cg04733989 chr22:42467013 NAGA -0.66 -9.37 -0.45 1.01e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs6942756 1.000 rs66538149 chr7:128974061 G/A cg02491457 chr7:128862824 NA -0.61 -8.9 -0.43 3.41e-17 White matter hyperintensity burden; LIHC cis rs4319547 0.698 rs10744217 chr12:122942070 A/G cg23029597 chr12:123009494 RSRC2 -0.47 -6.89 -0.35 2.72e-11 Body mass index; LIHC cis rs9790314 0.905 rs1154701 chr3:161008025 T/A cg03342759 chr3:160939853 NMD3 -0.72 -9.21 -0.45 3.3e-18 Morning vs. evening chronotype; LIHC cis rs7100689 0.556 rs3120976 chr10:82025682 C/A cg01528321 chr10:82214614 TSPAN14 0.81 10.8 0.5 1.4e-23 Post bronchodilator FEV1; LIHC cis rs7131987 0.650 rs10843382 chr12:29451721 G/A cg05697976 chr12:29376483 FAR2 0.3 6.17 0.32 1.9e-9 QT interval; LIHC cis rs35110281 0.774 rs2838323 chr21:44999086 G/A cg04455712 chr21:45112962 RRP1B 0.46 7.89 0.39 4.26e-14 Mean corpuscular volume; LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg07167872 chr1:205819463 PM20D1 0.53 7.76 0.39 9.78e-14 Menarche (age at onset); LIHC cis rs1707322 1.000 rs7517560 chr1:46425943 A/G cg06784218 chr1:46089804 CCDC17 0.35 6.39 0.33 5.45e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs11165623 0.792 rs2104236 chr1:96908690 C/T cg10631902 chr5:14652156 NA -0.34 -8.44 -0.42 9.11e-16 Hip circumference;Waist circumference; LIHC cis rs2180341 0.711 rs4371861 chr6:127568447 G/T cg27446573 chr6:127587934 RNF146 0.51 8.18 0.4 5.67e-15 Breast cancer; LIHC cis rs734999 0.545 rs12749591 chr1:2563250 G/T cg18854424 chr1:2615690 NA -0.34 -7.53 -0.38 4.63e-13 Ulcerative colitis; LIHC cis rs950776 0.518 rs8025429 chr15:78836362 G/A cg06917634 chr15:78832804 PSMA4 -0.9 -13.6 -0.59 5.5e-34 Sudden cardiac arrest; LIHC trans rs1814175 0.817 rs7950856 chr11:49976394 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs7582720 1.000 rs72926772 chr2:203804289 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg13393036 chr8:95962371 TP53INP1 -0.39 -8.44 -0.42 8.96e-16 Type 2 diabetes; LIHC cis rs27434 0.607 rs34750 chr5:96142806 G/C cg16492584 chr5:96139282 ERAP1 -0.34 -6.29 -0.32 9.79e-10 Ankylosing spondylitis; LIHC cis rs4243830 1.000 rs58415361 chr1:6592377 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.87 8.72 0.43 1.19e-16 Body mass index; LIHC cis rs903552 0.935 rs4965871 chr15:102003810 A/T cg19295451 chr15:102010161 PCSK6 -0.45 -6.44 -0.33 4.11e-10 Diabetic kidney disease; LIHC cis rs7927592 0.763 rs7119422 chr11:68331154 C/T cg20283391 chr11:68216788 NA 0.36 5.73 0.3 2.21e-8 Total body bone mineral density; LIHC cis rs9814567 1.000 rs934093 chr3:134195885 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.3 -0.55 4.71e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12980942 0.748 rs35501756 chr19:41823497 G/A cg25627403 chr19:41769009 HNRNPUL1 0.56 6.81 0.35 4.29e-11 Coronary artery disease; LIHC cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg17971929 chr21:40555470 PSMG1 -0.48 -7.24 -0.36 3.02e-12 Cognitive function; LIHC cis rs12216125 0.549 rs9358905 chr6:26077839 T/A cg17691542 chr6:26056736 HIST1H1C 0.44 6.23 0.32 1.39e-9 Iron status biomarkers; LIHC cis rs10411936 1.000 rs10411936 chr19:16548375 C/T cg10248733 chr19:16607483 C19orf44;CALR3 -0.43 -5.85 -0.3 1.12e-8 White blood cell count;Multiple sclerosis; LIHC cis rs7528419 1.000 rs7528419 chr1:109817192 A/G cg20569855 chr1:109824440 PSRC1 -0.53 -6.8 -0.34 4.79e-11 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs28735056 0.967 rs498541 chr18:77589655 G/A cg20368463 chr18:77673604 PQLC1 -0.38 -6.72 -0.34 7.74e-11 Schizophrenia; LIHC cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg11764359 chr7:65958608 NA 0.58 6.02 0.31 4.44e-9 Diabetic kidney disease; LIHC cis rs2282032 0.527 rs8009799 chr14:90766365 A/G cg04374321 chr14:90722782 PSMC1 0.49 7.07 0.36 8.56e-12 Longevity; LIHC cis rs1008375 0.966 rs4698636 chr4:17632834 T/C cg02297831 chr4:17616191 MED28 0.48 7.42 0.37 9.61e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs5769765 0.778 rs8137331 chr22:50313358 G/C cg02269571 chr22:50332266 NA -0.66 -9.1 -0.44 7.88e-18 Schizophrenia; LIHC cis rs1198430 0.639 rs16860685 chr1:23766644 A/G cg19827787 chr1:23763612 ASAP3 0.27 5.9 0.3 8.71e-9 Total cholesterol levels; LIHC cis rs11166927 1.000 rs13256625 chr8:140805003 G/T cg16909799 chr8:140841666 TRAPPC9 0.51 8.14 0.4 7.6e-15 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.65 -0.38 2e-13 Electroencephalogram traits; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.95 -0.31 6.51e-9 Total body bone mineral density; LIHC cis rs8016982 0.662 rs1957546 chr14:81639984 C/T cg01989461 chr14:81687754 GTF2A1 0.53 8.99 0.44 1.7e-17 Schizophrenia; LIHC cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.4 -0.37 1.07e-12 Bipolar disorder; LIHC cis rs7106204 0.609 rs12276488 chr11:24250211 G/A ch.11.24196551F chr11:24239977 NA 0.59 6.35 0.32 6.8e-10 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg12419862 chr22:24373484 LOC391322 -0.71 -10.84 -0.51 1.02e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2153535 0.580 rs9378554 chr6:8488468 C/T cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs1580019 0.510 rs4723162 chr7:32543804 C/A cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.25 0.45 2.54e-18 Cognitive ability; LIHC cis rs2033711 0.783 rs8113810 chr19:58932106 A/G cg26874164 chr19:58962979 ZNF324B 0.44 6.1 0.31 2.82e-9 Uric acid clearance; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20150972 chr6:13574573 SIRT5 0.41 6.29 0.32 9.92e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9914988 0.943 rs7211502 chr17:27163295 C/A cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs2153535 0.580 rs915350 chr6:8443486 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs754466 1.000 rs12220902 chr10:79682918 C/T cg17075019 chr10:79541650 NA -0.61 -8.26 -0.41 3.25e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs36051895 0.632 rs12352285 chr9:5141476 C/G cg02405213 chr9:5042618 JAK2 -0.67 -11.74 -0.54 5.62e-27 Pediatric autoimmune diseases; LIHC cis rs1577917 0.785 rs1885607 chr6:86394905 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.47 8.05 0.4 1.36e-14 Response to antipsychotic treatment; LIHC cis rs67478160 0.634 rs941473 chr14:104201869 C/G cg08213375 chr14:104286397 PPP1R13B 0.51 9.7 0.46 7.9e-20 Schizophrenia; LIHC trans rs2243480 1.000 rs73150014 chr7:65450919 A/C cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.71e-33 Diabetic kidney disease; LIHC cis rs11031096 0.568 rs10767891 chr11:4234524 A/G cg18678763 chr11:4115507 RRM1 -0.4 -5.97 -0.31 5.83e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs208520 0.690 rs12208977 chr6:66725257 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.91 0.43 3.16e-17 Exhaled nitric oxide output; LIHC cis rs7845219 0.544 rs34208552 chr8:95908067 C/G cg13393036 chr8:95962371 TP53INP1 -0.32 -6.06 -0.31 3.5e-9 Type 2 diabetes; LIHC trans rs11098499 0.874 rs6851169 chr4:120117510 T/C cg25214090 chr10:38739885 LOC399744 0.45 7.26 0.37 2.66e-12 Corneal astigmatism; LIHC cis rs11190604 1.000 rs10883507 chr10:102291275 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.09 0.4 1.05e-14 Palmitoleic acid (16:1n-7) levels; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg22212156 chr20:32031449 SNTA1 -0.42 -6.05 -0.31 3.72e-9 Neuroblastoma; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg07424592 chr7:64974309 NA -0.44 -6.69 -0.34 8.93e-11 Calcium levels; LIHC cis rs9911578 0.704 rs72628393 chr17:56585314 A/T cg05425664 chr17:57184151 TRIM37 0.58 8.42 0.41 1.01e-15 Intelligence (multi-trait analysis); LIHC cis rs3008870 1.000 rs12740884 chr1:67459855 C/A cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC trans rs5769707 0.837 rs5770599 chr22:50019981 C/G cg07964097 chr12:131708081 NA -0.23 -6.06 -0.31 3.66e-9 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9381040 0.610 rs6941090 chr6:41043465 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.22 -0.32 1.44e-9 Alzheimer's disease (late onset); LIHC cis rs2228479 0.702 rs11646374 chr16:89857935 G/A cg06558623 chr16:89946397 TCF25 0.85 11.09 0.51 1.32e-24 Skin colour saturation; LIHC cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.42 0.45 6.79e-19 Platelet count; LIHC trans rs9859557 0.904 rs6443732 chr3:180733341 G/A cg26202529 chr2:23865356 KLHL29 -0.43 -6.36 -0.33 6.62e-10 Schizophrenia; LIHC cis rs1707322 1.000 rs6672115 chr1:46272879 T/C cg06784218 chr1:46089804 CCDC17 0.37 6.51 0.33 2.76e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1580019 0.961 rs4357201 chr7:32496333 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.52 9.59 0.46 1.94e-19 Total body bone mineral density; LIHC cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg10802521 chr3:52805072 NEK4 -0.43 -7.12 -0.36 6.36e-12 Bipolar disorder; LIHC cis rs12893668 0.703 rs34186780 chr14:104027595 T/G cg24130564 chr14:104152367 KLC1 -0.57 -9.38 -0.45 9.31e-19 Reticulocyte count; LIHC cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg16822855 chr3:40428330 ENTPD3 0.35 6.38 0.33 5.91e-10 Renal cell carcinoma; LIHC cis rs7408868 1.000 rs7254269 chr19:15277429 A/T cg14696996 chr19:15285081 NOTCH3 -0.52 -6.98 -0.35 1.49e-11 Pulse pressure; LIHC cis rs7927771 0.864 rs4752999 chr11:47428565 C/T cg20135002 chr11:47629003 NA -0.58 -10.01 -0.48 7.32e-21 Subjective well-being; LIHC cis rs644799 1.000 rs680134 chr11:95559517 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.76 0.47 5.37e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 1.000 rs59275611 chr8:58195191 G/A cg21724239 chr8:58056113 NA 0.48 5.78 0.3 1.66e-8 Developmental language disorder (linguistic errors); LIHC cis rs9911578 0.835 rs723991 chr17:56482039 G/A cg12560992 chr17:57184187 TRIM37 -0.91 -15.09 -0.63 8.71e-40 Intelligence (multi-trait analysis); LIHC trans rs3960554 0.529 rs7793844 chr7:75883147 C/T cg19862616 chr7:65841803 NCRNA00174 0.61 9.54 0.46 2.89e-19 Eotaxin levels; LIHC cis rs5769765 0.773 rs7410291 chr22:50300078 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -9.3 -0.45 1.67e-18 Schizophrenia; LIHC cis rs1949733 0.523 rs56053534 chr4:8542876 G/A cg11789530 chr4:8429930 ACOX3 -0.59 -8.17 -0.4 6.22e-15 Response to antineoplastic agents; LIHC cis rs7131987 0.903 rs2216853 chr12:29413248 C/G cg00204748 chr12:29376779 FAR2 0.44 8.32 0.41 2.08e-15 QT interval; LIHC cis rs11758351 0.789 rs2069020 chr6:26205500 C/T cg03854865 chr6:26224070 HIST1H3E 0.62 7.12 0.36 6.29e-12 Gout;Renal underexcretion gout; LIHC cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg06640241 chr16:89574553 SPG7 0.79 14.57 0.62 9.46e-38 Multiple myeloma (IgH translocation); LIHC cis rs67460515 0.563 rs1585481 chr3:160901481 C/T cg03342759 chr3:160939853 NMD3 -0.62 -9.36 -0.45 1.09e-18 Parkinson's disease; LIHC cis rs4665809 0.549 rs7577896 chr2:26524493 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.49 6.21 0.32 1.52e-9 Gut microbiome composition (summer); LIHC cis rs10508774 0.733 rs12254344 chr10:32857229 G/A cg01819863 chr10:32635814 EPC1 0.61 5.83 0.3 1.31e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg26338869 chr17:61819248 STRADA 0.6 8.75 0.43 9.91e-17 Prudent dietary pattern; LIHC trans rs11098499 0.599 rs3864142 chr4:120266191 A/T cg25214090 chr10:38739885 LOC399744 0.44 7.16 0.36 5.09e-12 Corneal astigmatism; LIHC cis rs7078219 0.543 rs7096296 chr10:101277816 A/G cg06854084 chr10:101292507 NKX2-3 0.33 6.0 0.31 4.91e-9 Dental caries; LIHC cis rs763014 1.000 rs763014 chr16:675680 T/C cg27189623 chr16:705930 WDR90 0.42 6.91 0.35 2.43e-11 Height; LIHC cis rs892961 0.932 rs12453822 chr17:75416792 G/A cg05865280 chr17:75406074 SEPT9 0.62 12.15 0.55 1.72e-28 Airflow obstruction; LIHC trans rs11098499 0.615 rs59867181 chr4:120556467 C/T cg25214090 chr10:38739885 LOC399744 -0.44 -7.14 -0.36 5.69e-12 Corneal astigmatism; LIHC cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg16497277 chr3:49208875 KLHDC8B -0.5 -6.36 -0.32 6.65e-10 Menarche (age at onset); LIHC cis rs9733 0.596 rs6587516 chr1:150623221 C/T cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs3796352 1.000 rs114562844 chr3:52991584 C/T cg07884673 chr3:53033167 SFMBT1 0.88 6.5 0.33 2.77e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs4820539 1.000 rs3788347 chr22:23467804 G/A cg14186256 chr22:23484241 RTDR1 0.99 21.0 0.75 1.71e-63 Bone mineral density; LIHC cis rs1355223 0.583 rs2941057 chr11:34882220 G/A cg06937548 chr11:34938143 PDHX;APIP 0.41 5.85 0.3 1.17e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11190604 0.767 rs7085426 chr10:102163640 T/C cg07080220 chr10:102295463 HIF1AN 0.45 6.3 0.32 8.95e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2066819 1.000 rs11171803 chr12:56718422 T/C cg26714650 chr12:56694279 CS -1.39 -13.36 -0.59 4.78e-33 Psoriasis vulgaris; LIHC cis rs6061231 0.958 rs2379126 chr20:60953005 C/A cg06026331 chr20:60912101 LAMA5 0.44 6.13 0.31 2.43e-9 Colorectal cancer; LIHC trans rs637571 0.522 rs566590 chr11:65754062 C/T cg17712092 chr4:129076599 LARP1B 0.72 12.51 0.56 8.06e-30 Eosinophil percentage of white cells; LIHC cis rs4888262 0.545 rs8052923 chr16:74680105 C/T cg01733217 chr16:74700730 RFWD3 0.86 17.89 0.7 5.61e-51 Testicular germ cell tumor; LIHC trans rs1945213 0.694 rs1384088 chr11:55848713 G/C cg15704280 chr7:45808275 SEPT13 -0.59 -7.55 -0.38 4.02e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg00343986 chr7:65444356 GUSB 0.44 6.24 0.32 1.29e-9 Calcium levels; LIHC cis rs6840360 0.967 rs4696105 chr4:152606702 T/G cg22705602 chr4:152727874 NA -0.3 -6.33 -0.32 7.8e-10 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.48 0.62 2.2e-37 Prudent dietary pattern; LIHC cis rs9399135 0.967 rs2297338 chr6:135375762 G/A cg24558204 chr6:135376177 HBS1L 0.44 7.18 0.36 4.36e-12 Red blood cell count; LIHC cis rs3106136 0.649 rs7672613 chr4:95299150 G/A cg11021082 chr4:95130006 SMARCAD1 0.36 6.13 0.31 2.4e-9 Capecitabine sensitivity; LIHC cis rs11030122 0.702 rs12223176 chr11:3982537 T/G cg18678763 chr11:4115507 RRM1 -0.58 -8.56 -0.42 3.86e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs74544699 1.000 rs78267059 chr4:74798010 G/A cg16072462 chr4:74847758 PF4 0.6 6.14 0.32 2.27e-9 Growth-regulated protein alpha levels; LIHC trans rs2749592 0.550 rs9733309 chr10:37882405 G/A cg17830980 chr10:43048298 ZNF37B 0.42 7.94 0.39 3.02e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2439831 0.681 rs825740 chr15:43592408 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.71 10.47 0.49 1.94e-22 Lung cancer in ever smokers; LIHC cis rs644799 0.710 rs10831433 chr11:95519787 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.8 12.45 0.56 1.29e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs796364 0.906 rs281766 chr2:200820505 T/G cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.52e-9 Schizophrenia; LIHC cis rs2380220 0.808 rs2386669 chr6:95902121 C/T cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg25204440 chr1:209979598 IRF6 0.53 8.14 0.4 7.34e-15 Cleft lip with or without cleft palate; LIHC cis rs992157 0.735 rs13392177 chr2:219112956 C/T cg00012203 chr2:219082015 ARPC2 -0.91 -16.39 -0.66 5.74e-45 Colorectal cancer; LIHC cis rs4268898 0.636 rs72803210 chr2:24615710 A/G cg06627628 chr2:24431161 ITSN2 -0.73 -9.43 -0.45 6.25e-19 Asthma; LIHC cis rs921968 0.541 rs532425 chr2:219434194 A/G cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.63e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7131987 0.934 rs7316004 chr12:29411698 C/T cg14222432 chr12:29376421 FAR2 0.36 7.05 0.36 9.82e-12 QT interval; LIHC cis rs6701037 0.625 rs72719370 chr1:175128536 G/C cg17845761 chr1:175162550 KIAA0040 -0.43 -7.19 -0.36 4.16e-12 Alcohol dependence; LIHC cis rs644799 0.601 rs568878 chr11:95578694 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.65 9.82 0.47 3.2e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7131987 0.874 rs10843366 chr12:29407903 T/C cg14222432 chr12:29376421 FAR2 0.37 7.11 0.36 6.68e-12 QT interval; LIHC cis rs4604732 0.536 rs12049066 chr1:247642655 C/T cg02104434 chr1:247694406 LOC148824;OR2C3 0.26 6.19 0.32 1.74e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC trans rs2209875 1.000 rs2209875 chr9:91813461 G/A cg26057616 chr1:222234397 NA 0.37 6.15 0.32 2.21e-9 Pelvic organ prolapse (moderate/severe); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02775353 chr7:101814109 CUX1 0.45 6.14 0.32 2.27e-9 Hepatitis; LIHC cis rs11673344 0.864 rs8104919 chr19:37503783 G/A cg27390819 chr19:37464633 NA -0.51 -6.2 -0.32 1.66e-9 Obesity-related traits; LIHC cis rs929354 0.742 rs2006844 chr7:157002851 G/A cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.9e-9 Body mass index; LIHC cis rs6964587 1.000 rs12539231 chr7:91634963 G/A cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs11030122 0.673 rs4910597 chr11:4094923 G/A cg22027985 chr11:4115532 RRM1 -0.43 -5.73 -0.3 2.18e-8 Mean platelet volume;Platelet distribution width; LIHC cis rs933688 0.938 rs10063683 chr5:90714595 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.7 0.73 2.92e-58 Smoking behavior; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02949340 chr10:102820489 KAZALD1 -0.42 -6.45 -0.33 3.76e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs9522267 0.502 rs9515450 chr13:112234262 T/C cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.43e-8 Hepatitis; LIHC cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg02187348 chr16:89574699 SPG7 0.68 10.96 0.51 3.67e-24 Multiple myeloma (IgH translocation); LIHC cis rs13217239 0.574 rs9366680 chr6:27006123 A/T cg12292205 chr6:26970375 C6orf41 0.41 6.94 0.35 2.03e-11 Schizophrenia; LIHC cis rs10791097 0.608 rs12363140 chr11:130744268 A/C cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4638749 0.677 rs7599646 chr2:108852343 C/T cg25838818 chr2:108905173 SULT1C2 0.41 7.2 0.36 3.88e-12 Blood pressure; LIHC trans rs11098499 0.863 rs10004484 chr4:120442428 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.52 0.46 3.1400000000000002e-19 Corneal astigmatism; LIHC cis rs2295359 1.000 rs4655684 chr1:67611772 A/G cg12940439 chr1:67600707 NA -0.37 -6.61 -0.34 1.49e-10 Psoriasis; LIHC cis rs12477438 0.501 rs6727749 chr2:99793590 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg05527609 chr1:210001259 C1orf107 0.42 6.2 0.32 1.62e-9 Cleft lip with or without cleft palate; LIHC cis rs9309711 0.560 rs6548164 chr2:3472665 C/T cg10845886 chr2:3471009 TTC15 0.44 8.0 0.4 1.92e-14 Neurofibrillary tangles; LIHC cis rs9948 0.786 rs56797569 chr2:97413555 G/T cg01990225 chr2:97406019 LMAN2L -0.72 -6.23 -0.32 1.37e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1008375 1.000 rs9991307 chr4:17662408 A/G cg16339924 chr4:17578868 LAP3 0.41 5.91 0.3 8.45e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10256972 0.967 rs7799110 chr7:1039065 A/G cg04025307 chr7:1156635 C7orf50 0.48 7.95 0.4 2.7e-14 Longevity;Endometriosis; LIHC cis rs3008870 0.755 rs2815368 chr1:67500778 C/T cg02640540 chr1:67518911 SLC35D1 0.45 7.0 0.35 1.37e-11 Lymphocyte percentage of white cells; LIHC cis rs12950390 0.853 rs11079790 chr17:45853626 G/A cg03474202 chr17:45855739 NA -0.34 -5.9 -0.3 8.75e-9 IgG glycosylation; LIHC cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.73 -0.3 2.25e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12477438 0.501 rs2516833 chr2:99777405 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC trans rs9747201 0.926 rs34153075 chr17:80135728 C/A cg07393940 chr7:158741817 NA -0.56 -6.7 -0.34 8.72e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs72653721 0.689 rs61669862 chr6:11068598 T/C cg13562911 chr6:11044106 ELOVL2 0.51 7.54 0.38 4.23e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs8044868 0.530 rs2550870 chr16:72070129 C/T cg16558253 chr16:72132732 DHX38 -0.36 -5.78 -0.3 1.66e-8 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg05564831 chr3:52568323 NT5DC2 0.37 6.03 0.31 4.19e-9 Bipolar disorder; LIHC cis rs7474896 0.583 rs11011347 chr10:38019264 G/A cg25427524 chr10:38739819 LOC399744 -0.5 -7.33 -0.37 1.63e-12 Obesity (extreme); LIHC cis rs6952808 0.792 rs12531315 chr7:1953650 C/G cg02951883 chr7:2050386 MAD1L1 -0.62 -9.4 -0.45 7.84e-19 Bipolar disorder and schizophrenia; LIHC cis rs7116495 1.000 rs7116495 chr11:71762085 C/T cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg20295408 chr7:1910781 MAD1L1 0.49 7.04 0.36 1.04e-11 Bipolar disorder and schizophrenia; LIHC trans rs61931739 0.500 rs35030191 chr12:34548865 C/T cg26384229 chr12:38710491 ALG10B 0.79 9.68 0.46 9.64e-20 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27109971 chr18:267637 THOC1 0.45 6.44 0.33 4.05e-10 Pancreatic cancer; LIHC cis rs78456975 1.000 rs6730391 chr2:1566838 A/C cg01028140 chr2:1542097 TPO -0.48 -5.83 -0.3 1.25e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs11871801 0.517 rs684214 chr17:40696915 C/T cg14558262 chr17:40713999 COASY 0.5 6.91 0.35 2.44e-11 Crohn's disease; LIHC cis rs644799 1.000 rs564675 chr11:95561873 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs763121 0.706 rs3827356 chr22:39064806 G/T cg06022373 chr22:39101656 GTPBP1 -0.6 -10.38 -0.49 3.96e-22 Menopause (age at onset); LIHC cis rs9457247 0.534 rs4710149 chr6:167386346 T/C cg23791538 chr6:167370224 RNASET2 0.75 14.39 0.61 4.87e-37 Crohn's disease; LIHC cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg27286337 chr10:134555280 INPP5A 0.92 13.13 0.58 3.67e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12477438 0.520 rs13023744 chr2:99738224 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC cis rs644799 0.710 rs1852535 chr11:95501241 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.25 0.58 1.22e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4243830 0.510 rs7518459 chr1:6596678 C/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.95 -12.12 -0.55 2.25e-28 Body mass index; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg07133347 chr1:107600762 PRMT6 0.45 6.76 0.34 5.9e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4908768 0.911 rs6693127 chr1:8774973 G/A cg20416874 chr1:8611966 RERE 0.53 7.93 0.39 3.25e-14 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25334215 chr11:33163286 CSTF3 0.27 6.04 0.31 3.95e-9 Cognitive function; LIHC cis rs8017423 0.967 rs7158180 chr14:90729117 C/T cg14092571 chr14:90743983 NA -0.41 -6.53 -0.33 2.34e-10 Mortality in heart failure; LIHC cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg12311346 chr5:56204834 C5orf35 -0.54 -7.13 -0.36 6.06e-12 Initial pursuit acceleration; LIHC cis rs7772486 0.875 rs11755334 chr6:146399297 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -6.03 -0.31 4.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11077998 0.901 rs3794723 chr17:80529495 G/A cg10255544 chr17:80519551 FOXK2 0.48 8.53 0.42 4.71e-16 Reticulocyte fraction of red cells; LIHC cis rs600806 0.888 rs3879450 chr1:109909149 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC trans rs783540 1.000 rs783540 chr15:83254708 C/T cg18393722 chr15:85113863 UBE2QP1 0.38 6.61 0.34 1.48e-10 Schizophrenia; LIHC cis rs7615952 0.641 rs12491577 chr3:125731131 C/T cg05084668 chr3:125655381 ALG1L -0.39 -6.23 -0.32 1.4e-9 Blood pressure (smoking interaction); LIHC cis rs4908768 0.859 rs55802878 chr1:8666411 T/C cg20416874 chr1:8611966 RERE 0.52 7.41 0.37 9.9e-13 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs617791 0.530 rs7934543 chr11:65752508 G/T cg17712092 chr4:129076599 LARP1B -0.56 -6.8 -0.35 4.55e-11 Breast cancer; LIHC cis rs1559088 0.576 rs11084707 chr19:33612873 C/T cg17764715 chr19:33622953 WDR88 0.56 7.76 0.39 1.01e-13 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2576037 0.583 rs2164104 chr18:44567743 G/C cg19077165 chr18:44547161 KATNAL2 0.49 7.24 0.36 3e-12 Personality dimensions; LIHC cis rs875971 0.617 rs810400 chr7:66022889 G/C cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.03 12.86 0.57 3.86e-31 Alzheimer's disease; LIHC cis rs13392177 0.684 rs6720449 chr2:219080978 G/A cg00012203 chr2:219082015 ARPC2 -0.75 -11.27 -0.52 2.98e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs116248771 0.739 rs73156488 chr3:158413942 C/G cg16708174 chr3:158430962 RARRES1 0.49 6.48 0.33 3.25e-10 diarrhoeal disease at age 2; LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg03721293 chr16:90014378 DEF8 0.42 6.92 0.35 2.28e-11 Skin colour saturation; LIHC cis rs7208859 0.573 rs8078182 chr17:29149664 C/T cg13385521 chr17:29058706 SUZ12P 0.79 7.99 0.4 2.07e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg06481639 chr22:41940642 POLR3H -0.64 -6.63 -0.34 1.34e-10 Vitiligo; LIHC cis rs2742417 0.624 rs2742394 chr3:45757591 C/T cg04837898 chr3:45731254 SACM1L -0.53 -8.87 -0.43 4.05e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs11122272 0.735 rs2790873 chr1:231539685 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -10.33 -0.49 5.77e-22 Hemoglobin concentration; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg27432699 chr2:27873401 GPN1 -0.56 -8.19 -0.41 5.17e-15 Total body bone mineral density; LIHC cis rs875971 0.660 rs12698534 chr7:65986845 C/T cg00343986 chr7:65444356 GUSB 0.4 6.05 0.31 3.88e-9 Aortic root size; LIHC cis rs7589728 0.563 rs79892776 chr2:88470593 G/A cg04511125 chr2:88470314 THNSL2 0.98 10.01 0.48 7.2e-21 Plasma clusterin levels; LIHC cis rs12478296 0.901 rs73007142 chr2:243010852 T/C cg18898632 chr2:242989856 NA -0.7 -8.69 -0.43 1.58e-16 Obesity-related traits; LIHC cis rs9527 0.615 rs2152915 chr10:104691732 A/T cg15744005 chr10:104629667 AS3MT -0.29 -5.75 -0.3 1.98e-8 Arsenic metabolism; LIHC trans rs8030605 0.704 rs72740574 chr15:56637007 T/A cg01710580 chr16:598674 SOLH -0.66 -6.09 -0.31 3.08e-9 Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs950169 0.922 rs4842941 chr15:84831312 G/C cg12863693 chr15:85201151 NMB -0.4 -5.8 -0.3 1.47e-8 Schizophrenia; LIHC trans rs1902066 0.647 rs2503749 chr6:81349756 G/T cg07248951 chr1:36397042 EIF2C3 0.4 6.08 0.31 3.18e-9 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19850565 chr19:35168394 ZNF302 0.43 6.06 0.31 3.55e-9 Pancreatic cancer; LIHC trans rs7613875 0.600 rs2624832 chr3:50030858 C/T cg21659725 chr3:3221576 CRBN 0.55 8.21 0.41 4.51e-15 Body mass index; LIHC cis rs2180341 1.000 rs7776136 chr6:127638348 A/T cg27446573 chr6:127587934 RNF146 0.99 15.45 0.64 3.09e-41 Breast cancer; LIHC trans rs4824093 0.610 rs58671506 chr22:50288983 G/A cg09872104 chr7:134855509 C7orf49 -0.79 -6.33 -0.32 7.48e-10 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg24101359 chr6:42928495 GNMT 0.44 5.88 0.3 9.53e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs311392 0.902 rs419813 chr8:55092385 A/T cg20636351 chr8:55087400 NA -0.38 -7.73 -0.39 1.2e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs10870270 0.957 rs10870307 chr10:133780610 T/C cg08754478 chr10:133766260 PPP2R2D -0.54 -8.0 -0.4 1.92e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7937890 1.000 rs7937890 chr11:14396485 C/T cg02886208 chr11:14281011 SPON1 -0.57 -8.48 -0.42 6.68e-16 Mitochondrial DNA levels; LIHC cis rs12986413 0.624 rs2238599 chr19:2140009 C/T cg09261902 chr19:2140048 AP3D1 0.4 6.83 0.35 3.92e-11 Height; LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg11062466 chr8:58055876 NA 0.52 7.51 0.38 5.12e-13 Developmental language disorder (linguistic errors); LIHC cis rs7945071 0.507 rs1596295 chr11:110253214 G/A cg04157658 chr11:110243994 NA 0.33 6.08 0.31 3.15e-9 Cognitive function; LIHC cis rs4716602 0.573 rs34810003 chr7:156160883 T/C cg16983916 chr7:156159713 NA -0.32 -5.71 -0.3 2.43e-8 Anti-saccade response; LIHC cis rs4843747 0.641 rs11117353 chr16:88090895 A/G cg06050784 chr16:88016603 BANP 0.36 6.56 0.33 2.02e-10 Menopause (age at onset); LIHC cis rs2439831 1.000 rs2245054 chr15:43751909 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.57 0.59 7.69e-34 Lung cancer in ever smokers; LIHC cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.93 9.55 0.46 2.66e-19 Platelet count; LIHC cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg02290350 chr8:58132656 NA 0.46 8.88 0.43 3.78e-17 Developmental language disorder (linguistic errors); LIHC cis rs1707322 0.686 rs3014235 chr1:46091512 A/G cg03146154 chr1:46216737 IPP -0.55 -9.17 -0.44 4.62e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3806843 0.735 rs813897 chr5:140070029 T/C cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4555082 0.957 rs2735818 chr14:105714751 A/G cg10792982 chr14:105748885 BRF1 0.45 6.25 0.32 1.19e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs12586317 0.547 rs28569331 chr14:35473584 T/C cg05294307 chr14:35346193 BAZ1A -0.5 -7.42 -0.37 9.26e-13 Psoriasis; LIHC cis rs8067354 0.574 rs2531898 chr17:58012351 G/C cg02344993 chr17:57696989 CLTC 0.65 10.29 0.49 8.48e-22 Hemoglobin concentration; LIHC cis rs11122272 0.735 rs2066140 chr1:231504311 C/G cg06096015 chr1:231504339 EGLN1 0.5 9.22 0.45 3.22e-18 Hemoglobin concentration; LIHC cis rs2404602 0.610 rs28823285 chr15:77050395 T/C cg23625390 chr15:77176239 SCAPER -0.56 -9.5 -0.46 3.7e-19 Blood metabolite levels; LIHC trans rs4566357 0.615 rs6436644 chr2:227914275 T/A cg16088116 chr21:44841560 SIK1 -0.41 -6.27 -0.32 1.11e-9 Coronary artery disease; LIHC cis rs644799 1.000 rs527899 chr11:95529242 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9814567 1.000 rs9864439 chr3:134298671 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.41 -0.56 1.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.55 7.81 0.39 7.07e-14 Lymphocyte counts; LIHC cis rs9420 0.528 rs7117896 chr11:57388551 G/A cg19752551 chr11:57585705 CTNND1 -0.48 -6.21 -0.32 1.53e-9 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14934978 chr8:28352084 FZD3 -0.53 -6.27 -0.32 1.12e-9 Systolic blood pressure; LIHC cis rs250677 0.641 rs2915807 chr5:148450950 A/G cg23229984 chr5:148520753 ABLIM3 0.49 5.72 0.3 2.39e-8 Breast cancer; LIHC cis rs1707322 0.752 rs11211152 chr1:46114157 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.56 0.38 3.69e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1008375 0.932 rs964012 chr4:17619184 A/G cg16339924 chr4:17578868 LAP3 0.52 6.91 0.35 2.45e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs801193 1.000 rs10234018 chr7:66146284 A/T cg00343986 chr7:65444356 GUSB -0.41 -6.08 -0.31 3.23e-9 Aortic root size; LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg00800038 chr16:89945340 TCF25 0.63 10.06 0.48 5.2e-21 Skin colour saturation; LIHC cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs6690583 1.000 rs2304641 chr1:85513398 C/T cg22153463 chr1:85462885 MCOLN2 0.51 6.32 0.32 8.16e-10 Serum sulfate level; LIHC cis rs7044106 0.708 rs920745 chr9:123429943 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.59 0.38 3.04e-13 Hip circumference adjusted for BMI; LIHC cis rs8078723 0.866 rs3935280 chr17:38189055 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.55 9.06 0.44 1.02e-17 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs10752881 1.000 rs10737235 chr1:182971816 T/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.34 0.49 5.68e-22 Colorectal cancer; LIHC cis rs6596100 0.538 rs1393244 chr5:132186007 T/G cg02081065 chr5:132209139 LEAP2 0.27 6.1 0.31 2.89e-9 Breast cancer; LIHC trans rs9914544 0.545 rs9903574 chr17:18768582 C/T cg21372672 chr17:16614065 CCDC144A -0.28 -6.79 -0.34 5.11e-11 Educational attainment (years of education); LIHC cis rs1801251 1.000 rs283476 chr2:233650168 A/G cg25237894 chr2:233734115 C2orf82 0.56 11.06 0.51 1.61e-24 Coronary artery disease; LIHC trans rs1499614 1.000 rs1638731 chr7:66144679 C/T cg07424592 chr7:64974309 NA 0.77 8.94 0.44 2.49e-17 Gout; LIHC cis rs2412488 0.853 rs35089837 chr4:54354341 C/T cg22241045 chr4:54363911 LNX1 0.41 6.69 0.34 8.88e-11 DNA methylation (variation); LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg07677032 chr17:61819896 STRADA 0.43 6.25 0.32 1.23e-9 Prudent dietary pattern; LIHC cis rs7224685 0.569 rs7212168 chr17:4024640 G/A cg11204139 chr17:3907470 NA 0.6 6.98 0.35 1.49e-11 Type 2 diabetes; LIHC cis rs4713118 0.527 rs9461433 chr6:28095172 C/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Parkinson's disease; LIHC cis rs3096299 0.591 rs748940 chr16:89440757 T/A cg06640241 chr16:89574553 SPG7 0.63 9.92 0.47 1.45e-20 Multiple myeloma (IgH translocation); LIHC cis rs6754311 0.731 rs7569057 chr2:136583958 A/C cg17750252 chr2:136567154 LCT -0.33 -5.97 -0.31 6.06e-9 Mosquito bite size; LIHC cis rs1797081 0.967 rs780632 chr10:16861400 A/G cg23933602 chr10:16859644 RSU1 -1.01 -21.76 -0.76 1.58e-66 Platelet distribution width; LIHC cis rs9640161 0.711 rs55881542 chr7:150025734 G/A cg10018233 chr7:150070692 REPIN1 0.53 8.26 0.41 3.25e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs6701037 0.512 rs2285216 chr1:175133012 C/T cg17845761 chr1:175162550 KIAA0040 0.4 6.85 0.35 3.5e-11 Alcohol dependence; LIHC cis rs2404602 0.684 rs1603860 chr15:76849591 A/T cg03037974 chr15:76606532 NA -0.61 -10.3 -0.49 7.81e-22 Blood metabolite levels; LIHC cis rs11190604 1.000 rs2489035 chr10:102319395 C/T cg07080220 chr10:102295463 HIF1AN 0.53 7.32 0.37 1.82e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9916302 0.904 rs9905432 chr17:37555918 C/A cg07936489 chr17:37558343 FBXL20 0.85 13.54 0.59 1.01e-33 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg00091569 chr3:40428383 ENTPD3 0.38 6.39 0.33 5.33e-10 Renal cell carcinoma; LIHC cis rs12579753 1.000 rs10862368 chr12:82244514 C/T cg07988820 chr12:82153109 PPFIA2 -0.47 -5.78 -0.3 1.69e-8 Resting heart rate; LIHC cis rs13217239 0.646 rs6937880 chr6:27000236 C/T cg18867708 chr6:26865862 GUSBL1 0.52 8.03 0.4 1.64e-14 Schizophrenia; LIHC cis rs9993613 1.000 rs6446849 chr4:73459446 G/A cg15102770 chr4:73434591 ADAMTS3 -0.38 -6.14 -0.32 2.29e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs757081 0.667 rs569780 chr11:17206745 C/T cg15432903 chr11:17409602 KCNJ11 -0.43 -5.94 -0.31 7.08e-9 Systolic blood pressure; LIHC cis rs9394841 0.692 rs9394837 chr6:41848088 G/A cg17623882 chr6:41773611 USP49 -0.44 -5.91 -0.3 8.28e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs4684776 0.935 rs11714039 chr3:11365448 G/A cg00170343 chr3:11313890 ATG7 -0.51 -6.91 -0.35 2.31e-11 Small vessel stroke; LIHC cis rs3762637 1.000 rs7615673 chr3:122125544 G/C cg24169773 chr3:122142474 KPNA1 -0.45 -8.8 -0.43 7.1e-17 LDL cholesterol levels; LIHC cis rs2625529 0.775 rs4777477 chr15:72269612 G/A cg16672083 chr15:72433130 SENP8 -0.3 -5.73 -0.3 2.15e-8 Red blood cell count; LIHC cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg19774624 chr17:42201019 HDAC5 -0.67 -10.15 -0.48 2.47e-21 Total body bone mineral density; LIHC cis rs2180341 0.781 rs7760652 chr6:127572096 A/G cg27446573 chr6:127587934 RNF146 0.67 10.16 0.48 2.36e-21 Breast cancer; LIHC cis rs2842992 0.768 rs2273824 chr6:160211445 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.14 0.44 5.61e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs73001065 0.591 rs57009615 chr19:19613622 A/G cg03709012 chr19:19516395 GATAD2A 0.94 11.27 0.52 2.96e-25 LDL cholesterol; LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg24209194 chr3:40518798 ZNF619 -0.63 -9.6 -0.46 1.82e-19 Renal cell carcinoma; LIHC cis rs4969178 0.832 rs4969185 chr17:76398157 G/C cg20026190 chr17:76395443 PGS1 0.46 7.29 0.37 2.11e-12 HDL cholesterol levels; LIHC cis rs2073300 0.609 rs1076776 chr20:23427399 C/T cg12062639 chr20:23401060 NAPB -0.98 -12.8 -0.57 6.5e-31 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg08392591 chr16:89556376 ANKRD11 0.4 5.95 0.31 6.5e-9 Multiple myeloma (IgH translocation); LIHC cis rs10744422 1.000 rs10847869 chr12:123328359 C/G cg25930673 chr12:123319894 HIP1R -0.86 -11.24 -0.52 3.86e-25 Schizophrenia; LIHC cis rs739401 0.611 rs402276 chr11:3051404 C/G cg08508325 chr11:3079039 CARS -0.32 -6.87 -0.35 2.96e-11 Longevity; LIHC cis rs7100689 0.577 rs2282367 chr10:82040346 A/G cg00277334 chr10:82204260 NA -0.54 -6.42 -0.33 4.65e-10 Post bronchodilator FEV1; LIHC cis rs12971120 0.891 rs12608037 chr18:72169395 A/G cg25817165 chr18:72167213 CNDP2 -0.72 -12.53 -0.56 6.55e-30 Refractive error; LIHC cis rs1348850 0.914 rs1453370 chr2:178327727 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 13.9 0.6 4.07e-35 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2422052 0.530 rs11683225 chr2:118644135 C/A cg22545206 chr2:118617499 NA 0.37 6.17 0.32 1.88e-9 Mosquito bite size; LIHC cis rs780096 0.546 rs8179225 chr2:27737181 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -6.1 -0.31 2.84e-9 Total body bone mineral density; LIHC cis rs736408 0.677 rs1042779 chr3:52821011 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.45 7.32 0.37 1.83e-12 Bipolar disorder; LIHC trans rs877282 1.000 rs11253362 chr10:770979 G/T cg22713356 chr15:30763199 NA 1.34 12.73 0.57 1.22e-30 Uric acid levels; LIHC cis rs7208859 0.673 rs12103759 chr17:29235687 G/A cg14067834 chr17:29058358 SUZ12P 0.69 6.65 0.34 1.16e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9733 0.744 rs2089081 chr1:150800117 T/C cg17724175 chr1:150552817 MCL1 -0.37 -7.4 -0.37 1.09e-12 Tonsillectomy; LIHC cis rs7944584 0.545 rs7118178 chr11:47659135 G/A cg20307385 chr11:47447363 PSMC3 0.89 12.41 0.56 1.96e-29 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs79149102 0.579 rs76518150 chr15:75292721 C/G cg09165964 chr15:75287851 SCAMP5 -0.6 -7.78 -0.39 8.41e-14 Lung cancer; LIHC cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.81 0.3 1.4e-8 Schizophrenia; LIHC cis rs3749237 0.595 rs11130196 chr3:49490149 A/C cg02487422 chr3:49467188 NICN1 0.41 6.46 0.33 3.56e-10 Resting heart rate; LIHC cis rs736408 0.716 rs2300149 chr3:52822921 C/T cg10802521 chr3:52805072 NEK4 -0.37 -5.98 -0.31 5.53e-9 Bipolar disorder; LIHC cis rs8114671 0.562 rs6088646 chr20:33505937 T/C cg07148914 chr20:33460835 GGT7 0.65 9.86 0.47 2.42e-20 Height; LIHC cis rs9911578 0.967 rs405684 chr17:56777148 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.69 0.69 3.49e-50 Intelligence (multi-trait analysis); LIHC cis rs7618501 0.665 rs7621352 chr3:50070763 A/C cg24110177 chr3:50126178 RBM5 0.49 7.85 0.39 5.26e-14 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg12463550 chr7:65579703 CRCP 0.7 7.37 0.37 1.33e-12 Diabetic kidney disease; LIHC cis rs10870270 0.913 rs4880326 chr10:133745547 C/A cg26149184 chr10:133730230 NA 0.48 7.61 0.38 2.7e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs4319547 0.915 rs7966094 chr12:123115771 A/G cg23029597 chr12:123009494 RSRC2 -0.5 -6.93 -0.35 2.15e-11 Body mass index; LIHC cis rs929354 0.772 rs3802124 chr7:156970609 G/A cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs7503807 0.967 rs4889867 chr17:78593058 C/T cg09596252 chr17:78655493 RPTOR 0.4 7.09 0.36 7.58e-12 Obesity; LIHC cis rs57244997 1.000 rs73026551 chr6:162393642 A/C cg17173639 chr6:162384350 PARK2 -0.63 -7.6 -0.38 2.83e-13 Mosquito bite size; LIHC cis rs9858542 0.953 rs9827021 chr3:49514764 C/A cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg18305652 chr10:134549665 INPP5A 0.44 6.37 0.33 5.95e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12478296 0.892 rs11893879 chr2:243010411 G/A cg06360820 chr2:242988706 NA -0.82 -12.21 -0.55 1.02e-28 Obesity-related traits; LIHC cis rs7095944 0.554 rs11245344 chr10:126418782 C/T cg08799069 chr10:126477246 METTL10 -0.32 -5.86 -0.3 1.07e-8 Asthma; LIHC cis rs892961 0.899 rs747482 chr17:75412109 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.44 0.59 2.44e-33 Airflow obstruction; LIHC cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs9303280 0.806 rs9904624 chr17:38036586 A/G cg11212589 chr17:38028394 ZPBP2 0.35 7.09 0.36 7.92e-12 Self-reported allergy; LIHC cis rs9790314 1.000 rs6794601 chr3:160946769 C/T cg03342759 chr3:160939853 NMD3 -0.78 -11.0 -0.51 2.68e-24 Morning vs. evening chronotype; LIHC cis rs9611565 0.504 rs5758452 chr22:42144927 G/A cg03806693 chr22:41940476 POLR3H 0.76 8.48 0.42 6.74e-16 Vitiligo; LIHC cis rs1371867 0.846 rs1616833 chr8:101271821 C/T cg06636551 chr8:101224915 SPAG1 0.49 9.27 0.45 2.12e-18 Atrioventricular conduction; LIHC cis rs6088580 0.524 rs6088560 chr20:33228549 T/C cg07148914 chr20:33460835 GGT7 -0.49 -7.02 -0.36 1.18e-11 Glomerular filtration rate (creatinine); LIHC cis rs12477438 0.798 rs6761570 chr2:99577276 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.95 -0.47 1.22e-20 Chronic sinus infection; LIHC cis rs6516091 0.850 rs62199232 chr20:6050137 T/G cg25325723 chr20:6104886 FERMT1 -0.71 -5.88 -0.3 9.8e-9 Abdominal aortic aneurysm; LIHC cis rs12477438 0.520 rs8179690 chr2:99795300 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.88 -12.95 -0.57 1.76e-31 Chronic sinus infection; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg18050295 chr3:12949921 IQSEC1 0.43 7.1 0.36 7.34e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg00934597 chr7:893267 UNC84A -0.53 -7.76 -0.39 9.69e-14 Perceived unattractiveness to mosquitoes; LIHC cis rs8180040 0.739 rs12488225 chr3:47235107 G/A cg16586182 chr3:47516702 SCAP -0.51 -9.16 -0.44 4.8e-18 Colorectal cancer; LIHC cis rs548181 0.673 rs12288034 chr11:125570941 A/T cg03464685 chr11:125439445 EI24 -0.87 -9.46 -0.46 5.11e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg11235426 chr6:292522 DUSP22 -0.46 -6.27 -0.32 1.06e-9 Menopause (age at onset); LIHC cis rs3806843 0.766 rs801176 chr5:140087010 A/G cg16179182 chr5:140090404 VTRNA1-1 -0.35 -5.85 -0.3 1.18e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7208859 0.673 rs9899349 chr17:29200122 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs651907 0.535 rs11707250 chr3:101509371 A/T cg11279151 chr3:101281821 RG9MTD1 0.39 5.89 0.3 9.32e-9 Colorectal cancer; LIHC cis rs12478296 1.000 rs7603984 chr2:243047294 A/G cg18898632 chr2:242989856 NA -0.68 -8.55 -0.42 4.28e-16 Obesity-related traits; LIHC cis rs10089 1.000 rs1559263 chr5:127512873 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.37 0.33 5.93e-10 Ileal carcinoids; LIHC cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.41 0.45 7.29e-19 Bipolar disorder; LIHC cis rs1008375 0.932 rs2302391 chr4:17660237 T/C cg02297831 chr4:17616191 MED28 0.48 7.45 0.37 7.74e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9633740 0.545 rs2343306 chr10:82230146 A/G cg01528321 chr10:82214614 TSPAN14 -0.97 -13.09 -0.58 5.02e-32 Post bronchodilator FEV1; LIHC cis rs2933343 0.951 rs796862 chr3:128593040 G/A cg25356066 chr3:128598488 ACAD9 0.55 7.33 0.37 1.7e-12 IgG glycosylation; LIHC cis rs4969178 0.620 rs7219625 chr17:76390080 C/T cg20026190 chr17:76395443 PGS1 0.4 5.83 0.3 1.3e-8 HDL cholesterol levels; LIHC cis rs116095464 0.558 rs1541822 chr5:269234 A/C cg22496380 chr5:211416 CCDC127 1.04 10.72 0.5 2.69e-23 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01482980 chr7:92861284 CCDC132 0.46 6.82 0.35 4.18e-11 Cognitive function; LIHC trans rs875971 1.000 rs6957199 chr7:65978519 T/C cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.12e-10 Aortic root size; LIHC cis rs17001868 0.527 rs11913132 chr22:40778778 A/G cg07138101 chr22:40742427 ADSL 0.52 6.07 0.31 3.41e-9 Mammographic density (dense area); LIHC cis rs611744 0.647 rs631775 chr8:109252746 T/C cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs3936840 0.539 rs3742441 chr14:102970581 C/G cg10241871 chr14:102965420 TECPR2 -0.49 -7.42 -0.37 9.1e-13 Plateletcrit; LIHC cis rs1997103 1.000 rs4947499 chr7:55407196 T/C cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2153535 0.580 rs1932280 chr6:8473654 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18125265 chr1:6546646 PLEKHG5 0.47 7.09 0.36 7.65e-12 Pancreatic cancer; LIHC cis rs2479724 0.870 rs7766960 chr6:41918190 T/G cg17623882 chr6:41773611 USP49 -0.5 -7.4 -0.37 1.09e-12 Menarche (age at onset); LIHC cis rs798554 0.836 rs2260230 chr7:2822986 T/A cg13628971 chr7:2884303 GNA12 0.52 7.76 0.39 9.7e-14 Height; LIHC trans rs1994135 0.617 rs12821909 chr12:33723466 T/C cg26384229 chr12:38710491 ALG10B 0.48 6.45 0.33 3.84e-10 Resting heart rate; LIHC cis rs9420 0.961 rs499188 chr11:57434122 C/A cg19752551 chr11:57585705 CTNND1 -0.52 -7.35 -0.37 1.52e-12 Schizophrenia; LIHC cis rs55823223 0.564 rs936391 chr17:73847799 A/G cg19302996 chr17:73780495 UNK 0.48 6.28 0.32 1.01e-9 Psoriasis; LIHC cis rs17776563 0.887 rs8024142 chr15:89132693 G/A cg05013243 chr15:89149849 MIR1179 0.41 6.77 0.34 5.49e-11 Thyroid hormone levels; LIHC cis rs6762 0.550 rs8672 chr11:838634 C/G cg07691484 chr11:842764 TSPAN4;POLR2L -0.71 -8.99 -0.44 1.74e-17 Mean platelet volume; LIHC cis rs6088580 0.524 rs2889855 chr20:33276853 A/G cg08999081 chr20:33150536 PIGU -0.43 -7.48 -0.37 6.49e-13 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.87 0.57 3.48e-31 Prudent dietary pattern; LIHC cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg18305652 chr10:134549665 INPP5A 0.43 6.2 0.32 1.62e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10870270 0.784 rs10430614 chr10:133748640 C/T cg08754478 chr10:133766260 PPP2R2D 0.53 7.95 0.39 2.77e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs614226 0.935 rs2235222 chr12:120892193 G/C cg01236616 chr12:121019343 POP5 -1.24 -19.5 -0.73 1.76e-57 Type 1 diabetes nephropathy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15813570 chr14:64854563 MTHFD1 0.44 6.4 0.33 5.26e-10 Pancreatic cancer; LIHC cis rs17253792 0.822 rs79022053 chr14:56071721 A/G cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs2439831 0.850 rs12441127 chr15:44021175 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.69 0.34 8.9e-11 Lung cancer in ever smokers; LIHC cis rs28655083 0.828 rs9938028 chr16:77127830 A/C cg01753188 chr16:77233325 SYCE1L;MON1B 0.42 6.65 0.34 1.14e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9902453 1.000 rs62070270 chr17:28263980 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.67 0.53 1.01e-26 Coffee consumption (cups per day); LIHC cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.33 -0.32 7.64e-10 Gut microbiome composition (summer); LIHC cis rs11971779 0.680 rs2355788 chr7:139101897 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs8141529 0.702 rs469990 chr22:29304200 A/T cg15103426 chr22:29168792 CCDC117 0.57 9.24 0.45 2.71e-18 Lymphocyte counts; LIHC cis rs9517320 0.534 rs3825430 chr13:99129653 C/T cg20487152 chr13:99095054 FARP1 -0.39 -6.53 -0.33 2.41e-10 Longevity; LIHC cis rs12744310 0.887 rs35932978 chr1:41785445 A/C cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.92e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs250677 1.000 rs40525 chr5:148432932 G/T cg18129178 chr5:148520854 ABLIM3 0.43 6.76 0.34 6.05e-11 Breast cancer; LIHC cis rs7789940 0.951 rs7779014 chr7:75975586 C/T cg10167463 chr7:75959203 YWHAG -0.45 -7.06 -0.36 9.56e-12 Multiple sclerosis; LIHC cis rs748404 0.560 rs689797 chr15:43826557 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.39 5.87 0.3 1.05e-8 Lung cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25782445 chr7:99006594 BUD31;PDAP1 0.46 6.37 0.33 6.08e-10 Lung function (FEV1/FVC); LIHC cis rs4953318 0.577 rs67087783 chr2:46363544 C/T cg12428440 chr2:46370979 PRKCE 0.46 6.1 0.31 2.83e-9 Red blood cell count;Hematocrit;Red blood cell traits; LIHC trans rs561341 0.623 rs4795665 chr17:30233657 C/T cg20587970 chr11:113659929 NA -0.57 -7.14 -0.36 5.56e-12 Hip circumference adjusted for BMI; LIHC cis rs7091068 0.616 rs7084701 chr10:95482249 A/G cg20715218 chr10:95462985 C10orf4 0.54 5.82 0.3 1.32e-8 Urinary tract infection frequency; LIHC cis rs10847980 0.590 rs79798267 chr12:123321819 A/T cg18912006 chr12:123335444 HIP1R 0.72 7.39 0.37 1.11e-12 Adiponectin levels; LIHC cis rs2073300 0.609 rs6137929 chr20:23376357 G/A cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs1005277 0.579 rs2472181 chr10:38386764 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8103278 0.662 rs16980051 chr19:46345886 T/C cg14061069 chr19:46274453 DMPK -0.4 -6.33 -0.32 7.86e-10 Coronary artery disease; LIHC cis rs111326718 1 rs111326718 chr10:104771211 A/AAAAAT cg04362960 chr10:104952993 NT5C2 0.38 5.75 0.3 1.97e-8 Reticulocyte count; LIHC cis rs735396 1.000 rs735396 chr12:121438844 T/C cg02403541 chr12:121454288 C12orf43 0.47 8.28 0.41 2.78e-15 N-glycan levels; LIHC cis rs7662987 0.517 rs2602872 chr4:100038996 A/G cg13256891 chr4:100009986 ADH5 0.56 5.73 0.3 2.2e-8 Smoking initiation; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.84 0.63 8.42e-39 Prudent dietary pattern; LIHC cis rs1707322 0.752 rs11488313 chr1:46224780 G/C cg06784218 chr1:46089804 CCDC17 0.42 7.43 0.37 8.84e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2153535 0.580 rs2143357 chr6:8497196 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 2.04e-15 Motion sickness; LIHC cis rs3806843 1.000 rs9686540 chr5:140174622 G/A cg19875535 chr5:140030758 IK 0.36 5.9 0.3 8.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs950169 0.580 rs11635597 chr15:85165699 C/T cg12863693 chr15:85201151 NMB 0.49 7.06 0.36 9.47e-12 Schizophrenia; LIHC cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs711245 0.702 rs1110127 chr2:36768456 G/C cg01206211 chr2:36825736 FEZ2 0.45 7.35 0.37 1.48e-12 Height; LIHC cis rs9811920 0.638 rs704581 chr3:99556160 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 7.11 0.36 6.7e-12 Axial length; LIHC cis rs6442522 0.606 rs3773458 chr3:15495654 A/G cg16303742 chr3:15540471 COLQ 0.39 6.3 0.32 9.08e-10 Uric acid levels; LIHC cis rs4808199 0.947 rs10401193 chr19:19591066 A/G cg03709012 chr19:19516395 GATAD2A 1.07 19.22 0.72 2.49e-56 Nonalcoholic fatty liver disease; LIHC cis rs2991971 0.810 rs12119202 chr1:45925931 A/T cg24296786 chr1:45957014 TESK2 -0.53 -8.35 -0.41 1.75e-15 High light scatter reticulocyte count; LIHC cis rs1707322 0.963 rs12145287 chr1:46325002 C/G cg03146154 chr1:46216737 IPP 0.48 7.52 0.38 4.99e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs769267 0.930 rs751856 chr19:19602945 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.99 0.31 5.2e-9 Tonsillectomy; LIHC cis rs2354432 0.607 rs11587707 chr1:146707186 T/C cg25205988 chr1:146714368 CHD1L -0.9 -10.64 -0.5 5.17e-23 Mitochondrial DNA levels; LIHC trans rs2352908 0.786 rs6572526 chr14:49429557 G/A cg16568472 chr20:3190600 ITPA -0.45 -6.04 -0.31 3.92e-9 Social communication problems; LIHC cis rs892961 0.932 rs8066646 chr17:75414192 C/T cg01320579 chr17:75405842 SEPT9 0.52 7.44 0.37 8.37e-13 Airflow obstruction; LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC trans rs3960554 0.808 rs78340819 chr7:75673833 C/G cg19862616 chr7:65841803 NCRNA00174 0.6 8.37 0.41 1.45e-15 Eotaxin levels; LIHC trans rs10411161 0.748 rs56705839 chr19:52377236 A/G cg22319618 chr22:45562946 NUP50 -0.54 -6.81 -0.35 4.33e-11 Breast cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04371528 chr3:20081516 KAT2B 0.42 6.1 0.31 2.94e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg25894440 chr7:65020034 NA -0.41 -6.61 -0.34 1.48e-10 Calcium levels; LIHC cis rs12477438 0.798 rs10198293 chr2:99602929 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.6 -0.5 6.66e-23 Chronic sinus infection; LIHC cis rs921968 0.643 rs523396 chr2:219338789 T/G cg18887096 chr2:219472410 PLCD4 0.37 6.53 0.33 2.44e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7188697 0.922 rs37056 chr16:58560877 G/A cg02549819 chr16:58548995 SETD6 -0.46 -7.21 -0.36 3.65e-12 QT interval; LIHC trans rs17685 0.712 rs11770149 chr7:75791644 G/A cg19862616 chr7:65841803 NCRNA00174 0.78 14.14 0.61 4.63e-36 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11718455 0.961 rs3846068 chr3:44029835 G/A cg08738300 chr3:44038990 NA 0.52 9.24 0.45 2.77e-18 Coronary artery disease; LIHC trans rs1005277 0.529 rs1780125 chr10:38531376 A/G cg04469686 chr1:162760199 HSD17B7 -0.39 -6.04 -0.31 4.12e-9 Extrinsic epigenetic age acceleration; LIHC trans rs673253 0.686 rs2819333 chr1:44014573 A/T cg06090383 chr4:174292579 SAP30 -0.42 -6.15 -0.32 2.19e-9 Intelligence (multi-trait analysis); LIHC cis rs9309473 1.000 rs3813227 chr2:73651967 A/G cg20560298 chr2:73613845 ALMS1 0.52 6.46 0.33 3.56e-10 Metabolite levels; LIHC cis rs6963495 0.932 rs55700120 chr7:105148460 G/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs754466 0.580 rs11002294 chr10:79540588 T/C cg17075019 chr10:79541650 NA -0.79 -12.22 -0.55 9.41e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3820068 0.705 rs4646022 chr1:15839112 G/A cg17385448 chr1:15911702 AGMAT 0.38 6.7 0.34 8.52e-11 Systolic blood pressure; LIHC cis rs919433 0.679 rs10931787 chr2:198520615 A/G cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10751667 0.600 rs7395387 chr11:1008664 G/C cg10932868 chr11:921992 NA 0.33 5.99 0.31 5.32e-9 Alzheimer's disease (late onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg18850112 chr2:70329648 NA 0.44 6.54 0.33 2.2e-10 Hepatitis; LIHC cis rs13161895 1.000 rs12656814 chr5:179471556 G/A cg06664874 chr5:179499304 RNF130 0.61 7.56 0.38 3.66e-13 LDL cholesterol; LIHC cis rs12744310 0.887 rs12032040 chr1:41818307 C/T cg03962019 chr1:41807865 NA 0.4 6.38 0.33 5.74e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2842992 0.830 rs2273819 chr6:160183325 G/C cg11366901 chr6:160182831 ACAT2 0.94 16.17 0.66 4.53e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs9322817 0.902 rs7764251 chr6:105197091 G/T cg02098413 chr6:105308735 HACE1 -0.38 -6.13 -0.31 2.38e-9 Thyroid stimulating hormone; LIHC cis rs250677 0.687 rs40522 chr5:148442295 G/A cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs12477438 0.734 rs4851184 chr2:99666434 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.67 -0.53 1.03e-26 Chronic sinus infection; LIHC trans rs1459104 0.571 rs10459012 chr11:55091574 C/A cg03929089 chr4:120376271 NA 0.5 7.35 0.37 1.46e-12 Body mass index; LIHC cis rs9649465 0.967 rs7809453 chr7:123301940 A/G cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.59e-14 Migraine; LIHC cis rs4663866 0.901 rs34040298 chr2:239191607 T/C cg16914508 chr2:239161102 PER2 0.83 5.97 0.31 5.94e-9 Irritable bowel syndrome; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg04267008 chr7:1944627 MAD1L1 -0.67 -11.1 -0.51 1.16e-24 Bipolar disorder and schizophrenia; LIHC cis rs3106136 0.647 rs6532483 chr4:95293558 A/T cg11021082 chr4:95130006 SMARCAD1 0.35 5.98 0.31 5.48e-9 Capecitabine sensitivity; LIHC cis rs2637266 1.000 rs2395410 chr10:78381767 C/T cg18941641 chr10:78392320 NA 0.28 6.04 0.31 4.12e-9 Pulmonary function; LIHC cis rs2933343 0.700 rs2630257 chr3:128644015 T/C cg25356066 chr3:128598488 ACAD9 0.52 7.21 0.36 3.68e-12 IgG glycosylation; LIHC cis rs12220238 1.000 rs10824113 chr10:75969018 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.22 0.32 1.47e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs6502050 0.731 rs4789730 chr17:80145983 T/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.92 -0.31 7.68e-9 Life satisfaction; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26398333 chr1:153895721 GATAD2B 0.49 6.99 0.35 1.41e-11 Pancreatic cancer; LIHC cis rs7617773 0.780 rs34589064 chr3:48339549 G/A cg11946769 chr3:48343235 NME6 0.92 11.62 0.53 1.58e-26 Coronary artery disease; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs7246657 1.000 rs7247672 chr19:37743928 A/G cg23950597 chr19:37808831 NA -0.52 -6.63 -0.34 1.34e-10 Coronary artery calcification; LIHC cis rs6062302 0.522 rs3810492 chr20:62219740 G/A cg16989086 chr20:62203971 PRIC285 0.52 7.4 0.37 1.09e-12 Glioblastoma; LIHC cis rs10128251 0.962 rs10752281 chr10:5711220 C/T cg24097872 chr10:5724021 NA -0.77 -11.11 -0.52 1.05e-24 Childhood ear infection; LIHC cis rs1046896 0.514 rs9894705 chr17:80823758 A/C cg22027946 chr17:80790580 TBCD;ZNF750 -0.5 -7.22 -0.36 3.32e-12 Glycated hemoglobin levels; LIHC cis rs10791097 0.690 rs12284487 chr11:130729705 T/C cg09137382 chr11:130731461 NA 0.41 6.16 0.32 2.07e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs694739 0.628 rs617051 chr11:64133638 C/A cg23796481 chr11:64053134 BAD;GPR137 0.46 6.22 0.32 1.42e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs6570726 0.935 rs425731 chr6:145834151 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg00825309 chr19:58991885 ZNF446 -0.53 -8.17 -0.4 6.22e-15 Uric acid clearance; LIHC cis rs12478296 0.534 rs67092377 chr2:243002171 T/G cg06360820 chr2:242988706 NA -0.74 -11.1 -0.51 1.22e-24 Obesity-related traits; LIHC cis rs9649213 0.593 rs11766808 chr7:97915376 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs986417 0.901 rs7160405 chr14:60970004 G/C cg27398547 chr14:60952738 C14orf39 0.85 9.85 0.47 2.61e-20 Gut microbiota (bacterial taxa); LIHC cis rs3096299 0.935 rs3102387 chr16:89432276 A/C cg06640241 chr16:89574553 SPG7 0.62 9.68 0.46 9.32e-20 Multiple myeloma (IgH translocation); LIHC cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg15691649 chr6:25882328 NA 0.77 10.33 0.49 5.74e-22 Blood metabolite levels; LIHC cis rs875971 0.792 rs6971752 chr7:65737986 G/A cg18876405 chr7:65276391 NA -0.35 -6.37 -0.33 6.12e-10 Aortic root size; LIHC cis rs7546668 1.000 rs7546668 chr1:15855123 G/C cg11706911 chr1:15910989 AGMAT 0.45 6.97 0.35 1.67e-11 Glomerular filtration rate (creatinine); LIHC cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.61e-12 Bipolar disorder; LIHC cis rs3768617 0.811 rs12043805 chr1:183008150 T/A ch.1.3577855R chr1:183094577 LAMC1 0.48 7.61 0.38 2.64e-13 Fuchs's corneal dystrophy; LIHC cis rs66887589 0.967 rs1480933 chr4:120433248 C/T cg09307838 chr4:120376055 NA 0.46 6.98 0.35 1.55e-11 Diastolic blood pressure; LIHC cis rs7212590 0.618 rs59767604 chr17:58041339 C/G cg10252138 chr17:58120427 NA -0.6 -6.07 -0.31 3.35e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs72653721 0.689 rs4713160 chr6:11057513 T/A cg13562911 chr6:11044106 ELOVL2 0.51 7.53 0.38 4.55e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg09417038 chr21:47716443 C21orf57 -0.54 -8.11 -0.4 9.2e-15 Testicular germ cell tumor; LIHC cis rs2425143 1.000 rs6060591 chr20:34351476 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.53 -6.89 -0.35 2.64e-11 Blood protein levels; LIHC cis rs2153535 0.580 rs1360054 chr6:8520377 C/A cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.22e-26 Motion sickness; LIHC cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.99 0.51 2.87e-24 Platelet count; LIHC trans rs78049276 0.688 rs75697049 chr4:148375242 C/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.62 -7.6 -0.38 2.94e-13 Pulse pressure; LIHC cis rs7772486 0.743 rs9390344 chr6:146012755 C/G cg23711669 chr6:146136114 FBXO30 -0.59 -10.77 -0.5 1.71e-23 Lobe attachment (rater-scored or self-reported); LIHC trans rs6600671 1.000 rs1591882 chr1:121183313 G/A cg09829573 chr1:144692074 NBPF9 -0.42 -7.62 -0.38 2.45e-13 Hip geometry; LIHC trans rs1499614 0.901 rs2178742 chr7:66197799 G/A cg10756647 chr7:56101905 PSPH 1.0 11.73 0.54 5.99e-27 Gout; LIHC cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg12310025 chr6:25882481 NA 0.49 6.1 0.31 2.89e-9 Intelligence (multi-trait analysis); LIHC cis rs9399135 0.660 rs4646868 chr6:135271946 A/G cg24558204 chr6:135376177 HBS1L 0.45 7.25 0.36 2.81e-12 Red blood cell count; LIHC cis rs240764 0.817 rs12216304 chr6:101174161 A/G cg09795085 chr6:101329169 ASCC3 -0.51 -7.04 -0.36 1.08e-11 Neuroticism; LIHC cis rs7903847 0.642 rs10882908 chr10:99134970 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.6 -0.34 1.57e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9513627 1.000 rs4294655 chr13:100216696 A/G cg25919922 chr13:100150906 NA 0.78 7.03 0.36 1.13e-11 Obesity-related traits; LIHC cis rs12477438 0.520 rs6542863 chr2:99725138 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.53 0.64 1.5e-41 Chronic sinus infection; LIHC cis rs748404 0.697 rs555001 chr15:43545728 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.43 6.53 0.33 2.35e-10 Lung cancer; LIHC cis rs7945705 0.818 rs2653613 chr11:8879105 C/T cg12365402 chr11:9010492 NRIP3 -0.25 -6.32 -0.32 8.25e-10 Hemoglobin concentration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23891596 chr19:50169132 IRF3;BCL2L12 0.48 7.03 0.36 1.13e-11 Lung function (FEV1/FVC); LIHC trans rs2243480 0.901 rs3813708 chr7:65305632 C/A cg10756647 chr7:56101905 PSPH 1.11 13.27 0.58 1.06e-32 Diabetic kidney disease; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg10150615 chr22:24372951 LOC391322 -0.52 -7.54 -0.38 4.13e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6960043 0.818 rs10950546 chr7:15050391 C/T cg19272540 chr7:15055459 NA 0.26 7.01 0.35 1.26e-11 Type 2 diabetes; LIHC cis rs2635047 1.000 rs2684826 chr18:44679147 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.45 6.0 0.31 5.09e-9 Educational attainment; LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs1215050 1.000 rs1215050 chr4:98849826 A/G cg05340658 chr4:99064831 C4orf37 -0.45 -6.24 -0.32 1.3e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg19318889 chr4:1322082 MAEA -0.48 -7.99 -0.4 2.05e-14 Obesity-related traits; LIHC cis rs116095464 0.510 rs7714944 chr5:231765 C/T cg22496380 chr5:211416 CCDC127 -1.02 -10.43 -0.49 2.72e-22 Breast cancer; LIHC cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg07092213 chr7:1199455 ZFAND2A -0.44 -6.32 -0.32 7.98e-10 Longevity;Endometriosis; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.51 0.33 2.68e-10 Bipolar disorder; LIHC cis rs10838687 0.867 rs2957873 chr11:47249294 G/A cg25783544 chr11:47291846 MADD -0.5 -6.53 -0.33 2.36e-10 Proinsulin levels; LIHC cis rs25645 0.502 rs1563103 chr17:38111740 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.49 -7.29 -0.37 2.19e-12 Myeloid white cell count; LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.1 0.4 9.76e-15 Height; LIHC cis rs10751667 0.961 rs7482484 chr11:927020 C/T cg06064525 chr11:970664 AP2A2 -0.49 -12.06 -0.55 3.7e-28 Alzheimer's disease (late onset); LIHC cis rs3791556 0.501 rs3791536 chr2:240101713 G/A cg03281426 chr2:240109471 HDAC4 0.39 6.31 0.32 8.74e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2836950 0.520 rs2836966 chr21:40637521 A/G cg06238570 chr21:40685208 BRWD1 -0.44 -7.11 -0.36 6.88e-12 Menarche (age at onset); LIHC cis rs7683537 0.725 rs28837443 chr4:185641497 G/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Systemic lupus erythematosus; LIHC cis rs9399135 0.967 rs2297340 chr6:135376058 T/C cg24558204 chr6:135376177 HBS1L 0.44 7.18 0.36 4.36e-12 Red blood cell count; LIHC cis rs1728785 1.000 rs1645981 chr16:68571648 T/C cg02972257 chr16:68554789 NA -0.56 -6.45 -0.33 3.89e-10 Ulcerative colitis; LIHC cis rs9467773 0.967 rs1535276 chr6:26520941 T/C cg09904177 chr6:26538194 HMGN4 0.66 13.86 0.6 5.82e-35 Intelligence (multi-trait analysis); LIHC cis rs6120849 0.663 rs13041792 chr20:33545055 G/A cg06115741 chr20:33292138 TP53INP2 0.49 5.89 0.3 9.12e-9 Protein C levels; LIHC cis rs2404602 0.647 rs10851889 chr15:77023336 C/T cg23625390 chr15:77176239 SCAPER -0.55 -9.23 -0.45 2.94e-18 Blood metabolite levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07466437 chr6:8086756 EEF1E1;SCARNA27 -0.37 -6.11 -0.31 2.72e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2832077 0.527 rs9981922 chr21:30212718 A/G cg14791747 chr16:20752902 THUMPD1 0.8 12.68 0.57 1.83e-30 Cognitive test performance; LIHC cis rs67981189 0.593 rs3784067 chr14:71480178 G/C cg15816911 chr14:71606274 NA 0.39 6.18 0.32 1.81e-9 Schizophrenia; LIHC cis rs13108904 0.901 rs13112706 chr4:1303682 G/T cg13395646 chr4:1353034 KIAA1530 -0.67 -9.57 -0.46 2.15e-19 Obesity-related traits; LIHC cis rs422249 0.512 rs174561 chr11:61582708 T/C cg07689907 chr11:61582574 FADS1 0.41 5.96 0.31 6.39e-9 Trans fatty acid levels; LIHC cis rs10751667 1.000 rs7396798 chr11:970510 G/T cg06064525 chr11:970664 AP2A2 -0.5 -12.47 -0.56 1.14e-29 Alzheimer's disease (late onset); LIHC cis rs6089584 0.927 rs2296083 chr20:60574216 C/T cg13770153 chr20:60521292 NA -0.33 -6.57 -0.33 1.9e-10 Body mass index; LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg16132339 chr22:24313637 DDTL;DDT 0.67 12.8 0.57 6.41e-31 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1355223 0.902 rs1588353 chr11:34730814 A/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.39 -0.33 5.45e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19280121 chr17:21117780 TMEM11 0.43 6.14 0.32 2.24e-9 Pancreatic cancer; LIHC cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg03517284 chr6:25882590 NA -0.48 -5.8 -0.3 1.48e-8 Intelligence (multi-trait analysis); LIHC cis rs1580019 0.568 rs2122633 chr7:32523870 G/T cg14728415 chr7:32535168 LSM5;AVL9 0.42 6.14 0.32 2.3e-9 Cognitive ability; LIHC cis rs10089 0.909 rs7732599 chr5:127370421 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.74 0.34 6.7e-11 Ileal carcinoids; LIHC cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg11764359 chr7:65958608 NA 0.55 5.83 0.3 1.29e-8 Diabetic kidney disease; LIHC cis rs7833790 0.636 rs12544174 chr8:82731477 G/A cg02079420 chr8:82753780 SNX16 0.37 6.8 0.34 4.77e-11 Diastolic blood pressure; LIHC cis rs1707322 1.000 rs11211239 chr1:46451947 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7219021 1.000 rs7219021 chr17:46840541 A/C cg14968300 chr8:23585186 NA -0.33 -6.22 -0.32 1.43e-9 Schizophrenia or bipolar disorder; LIHC cis rs6960043 0.714 rs6976086 chr7:15048611 T/G cg19272540 chr7:15055459 NA 0.27 7.33 0.37 1.69e-12 Type 2 diabetes; LIHC cis rs2573652 0.928 rs2581348 chr15:100514063 C/T cg09918751 chr15:100517450 ADAMTS17 -0.79 -14.06 -0.61 9.24e-36 Height; LIHC cis rs2153535 0.542 rs6912740 chr6:8439959 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.69 0.53 8.72e-27 Motion sickness; LIHC cis rs875971 0.767 rs1695815 chr7:65831344 A/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs722599 0.715 rs11851433 chr14:75339450 C/T cg11812906 chr14:75593930 NEK9 0.39 6.1 0.31 2.94e-9 IgG glycosylation; LIHC cis rs3741404 0.825 rs11603384 chr11:63949095 G/A cg18225595 chr11:63971243 STIP1 0.68 10.63 0.5 5.23e-23 Platelet count; LIHC cis rs208520 0.837 rs208488 chr6:66926902 C/T cg07460842 chr6:66804631 NA -0.78 -8.51 -0.42 5.6e-16 Exhaled nitric oxide output; LIHC cis rs1707322 0.752 rs12062535 chr1:46222880 G/A cg03146154 chr1:46216737 IPP 0.57 9.3 0.45 1.69e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs950776 0.593 rs555018 chr15:78879242 G/A cg22563815 chr15:78856949 CHRNA5 -0.32 -5.73 -0.3 2.2e-8 Sudden cardiac arrest; LIHC cis rs35306767 0.716 rs34487581 chr10:897201 G/A cg20503657 chr10:835505 NA 1.34 14.36 0.61 6.27e-37 Eosinophil percentage of granulocytes; LIHC trans rs875971 0.545 rs1796222 chr7:66057154 T/C cg26939375 chr7:64535504 NA -0.38 -6.07 -0.31 3.32e-9 Aortic root size; LIHC cis rs2180341 0.855 rs9385422 chr6:127716457 C/T cg24812749 chr6:127587940 RNF146 0.84 13.35 0.59 4.99e-33 Breast cancer; LIHC cis rs3812831 0.662 rs407531 chr13:114929218 G/A cg08824895 chr13:115047677 UPF3A 0.49 6.98 0.35 1.51e-11 Schizophrenia; LIHC cis rs8017423 0.935 rs11626869 chr14:90788985 A/G cg14092571 chr14:90743983 NA 0.43 6.88 0.35 2.89e-11 Mortality in heart failure; LIHC cis rs2991971 0.810 rs998199 chr1:45912898 A/C cg15605315 chr1:45957053 TESK2 -0.51 -7.26 -0.37 2.65e-12 High light scatter reticulocyte count; LIHC cis rs1003719 0.680 rs2835668 chr21:38580151 C/G cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.23 -0.48 1.3e-21 Eye color traits; LIHC cis rs3008870 0.701 rs2815358 chr1:67493778 T/C cg02640540 chr1:67518911 SLC35D1 0.43 6.8 0.35 4.68e-11 Lymphocyte percentage of white cells; LIHC cis rs1691799 0.899 rs1168320 chr12:66744849 C/T cg16791601 chr12:66731901 HELB -0.57 -13.96 -0.6 2.36e-35 White blood cell count (basophil); LIHC cis rs6570726 0.738 rs7746330 chr6:145899257 A/C cg23711669 chr6:146136114 FBXO30 0.74 12.78 0.57 7.66e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs96067 0.711 rs795047 chr1:36637708 C/T cg24686825 chr1:36642396 MAP7D1 0.38 7.07 0.36 8.66e-12 Corneal structure; LIHC cis rs35306767 0.855 rs12761180 chr10:872086 C/T cg10556349 chr10:835070 NA 0.67 5.85 0.3 1.13e-8 Eosinophil percentage of granulocytes; LIHC cis rs7937890 0.810 rs10734224 chr11:14424124 G/T cg22961513 chr11:14280813 SPON1 -0.43 -6.45 -0.33 3.82e-10 Mitochondrial DNA levels; LIHC cis rs908922 0.887 rs4596895 chr1:152528075 T/G cg20991723 chr1:152506922 NA 0.39 5.91 0.3 8.08e-9 Hair morphology; LIHC cis rs11098499 0.743 rs10003567 chr4:120241674 C/T cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs1670533 1.000 rs11735663 chr4:1051845 C/T cg27284194 chr4:1044797 NA 0.6 8.95 0.44 2.35e-17 Recombination rate (females); LIHC cis rs7703744 0.747 rs7707470 chr5:118680273 G/A cg04195774 chr5:118677172 TNFAIP8 -0.41 -5.78 -0.3 1.71e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs637571 0.510 rs10750772 chr11:65577427 C/T cg17712092 chr4:129076599 LARP1B -0.7 -10.23 -0.48 1.32e-21 Eosinophil percentage of white cells; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg08493338 chr16:354269 AXIN1 0.42 6.32 0.32 8.16e-10 Bilirubin levels; LIHC cis rs3106136 0.967 rs8026 chr4:95212185 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.9 -0.39 3.77e-14 Capecitabine sensitivity; LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg15586393 chr4:1244086 CTBP1;C4orf42 -0.4 -5.77 -0.3 1.78e-8 Longevity; LIHC cis rs34779708 0.966 rs4934539 chr10:35472199 A/G cg03585969 chr10:35415529 CREM 0.86 13.05 0.58 7.33e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4878497 0.582 rs7874563 chr9:32443974 T/C cg14296220 chr9:32431791 ACO1 0.57 9.82 0.47 3.27e-20 Inflammatory skin disease; LIHC cis rs3790645 1.000 rs282175 chr1:26895802 A/G cg23229016 chr1:26872525 RPS6KA1 0.23 6.02 0.31 4.41e-9 Glucose homeostasis traits; LIHC cis rs7116495 1.000 rs531326 chr11:71570656 A/G cg26138937 chr11:71823887 C11orf51 0.69 6.63 0.34 1.32e-10 Severe influenza A (H1N1) infection; LIHC cis rs17685 0.671 rs60303271 chr7:75760008 A/G cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg14709524 chr16:89940631 TCF25 0.54 7.0 0.35 1.33e-11 Skin colour saturation; LIHC cis rs7100689 0.599 rs946892 chr10:82127551 C/T cg01528321 chr10:82214614 TSPAN14 0.77 10.16 0.48 2.34e-21 Post bronchodilator FEV1; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg22963979 chr7:1858916 MAD1L1 -0.44 -7.18 -0.36 4.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs1030268 0.651 rs12707118 chr7:133474900 C/T cg10665199 chr7:133106180 EXOC4 -0.43 -6.08 -0.31 3.16e-9 Intelligence (multi-trait analysis); LIHC cis rs8084351 0.524 rs10853628 chr18:50770638 T/C cg24270629 chr18:50823537 DCC -0.46 -6.84 -0.35 3.56e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs1005277 0.563 rs2800550 chr10:38482929 T/C cg17830980 chr10:43048298 ZNF37B -0.52 -10.18 -0.48 2e-21 Extrinsic epigenetic age acceleration; LIHC trans rs4566357 0.595 rs10201538 chr2:227914449 A/G cg16088116 chr21:44841560 SIK1 -0.41 -6.39 -0.33 5.52e-10 Coronary artery disease; LIHC cis rs8084351 0.577 rs4453578 chr18:50620752 A/G cg24270629 chr18:50823537 DCC 0.44 6.7 0.34 8.42e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs17125944 0.686 rs73304351 chr14:53375140 G/A cg00686598 chr14:53173677 PSMC6 0.91 9.65 0.46 1.23e-19 Alzheimer's disease (late onset); LIHC cis rs67478160 0.643 rs12891175 chr14:104274166 T/C cg08213375 chr14:104286397 PPP1R13B 0.64 12.57 0.56 4.76e-30 Schizophrenia; LIHC cis rs782590 0.967 rs4290693 chr2:55799991 C/G cg03859395 chr2:55845619 SMEK2 0.83 14.77 0.62 1.52e-38 Metabolic syndrome; LIHC cis rs3762637 0.941 rs9863712 chr3:122099906 C/T cg24169773 chr3:122142474 KPNA1 -0.48 -9.29 -0.45 1.82e-18 LDL cholesterol levels; LIHC cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg22105103 chr4:187893119 NA -0.35 -8.63 -0.42 2.42e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs950169 0.580 rs17598114 chr15:85171317 C/T cg17507749 chr15:85114479 UBE2QP1 0.69 7.99 0.4 2.07e-14 Schizophrenia; LIHC cis rs2303759 0.830 rs7257053 chr19:49894456 C/G cg24324837 chr19:49891574 CCDC155 0.39 6.07 0.31 3.38e-9 Multiple sclerosis; LIHC cis rs992157 0.764 rs2891076 chr2:219184398 C/T cg00012203 chr2:219082015 ARPC2 0.75 10.52 0.49 1.33e-22 Colorectal cancer; LIHC cis rs903552 1.000 rs12915569 chr15:102001883 G/A cg19295451 chr15:102010161 PCSK6 -0.43 -5.87 -0.3 1e-8 Diabetic kidney disease; LIHC cis rs4555082 0.834 rs2735822 chr14:105712734 C/T cg06808227 chr14:105710500 BRF1 -0.49 -6.1 -0.31 2.89e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs1707322 0.752 rs6662164 chr1:46146230 T/A cg06784218 chr1:46089804 CCDC17 0.39 7.28 0.37 2.32e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9475752 0.744 rs9464407 chr6:56779570 A/G cg25726699 chr6:135826776 C6orf217 0.4 6.09 0.31 2.99e-9 Menarche (age at onset); LIHC cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg23758822 chr17:41437982 NA 0.94 17.86 0.69 7.08e-51 Menopause (age at onset); LIHC cis rs6684514 1.000 rs12142808 chr1:156230546 G/A cg16558208 chr1:156270281 VHLL 0.51 9.29 0.45 1.81e-18 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC trans rs459571 0.959 rs410876 chr9:136893867 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.58 -9.1 -0.44 7.52e-18 Platelet distribution width; LIHC cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg06634786 chr22:41940651 POLR3H 0.73 7.59 0.38 3.16e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs354225 0.608 rs168505 chr2:54920968 C/T cg26097391 chr2:54893211 SPTBN1 0.44 6.26 0.32 1.18e-9 Schizophrenia; LIHC trans rs11098499 0.954 rs2892848 chr4:120381341 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs1568889 0.838 rs11030220 chr11:28145769 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.18 0.61 3.24e-36 Bipolar disorder; LIHC cis rs7208859 0.623 rs8081299 chr17:29104296 G/A cg14067834 chr17:29058358 SUZ12P 0.71 7.01 0.35 1.26e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg21724239 chr8:58056113 NA 0.56 7.38 0.37 1.24e-12 Developmental language disorder (linguistic errors); LIHC cis rs2197308 0.740 rs10880619 chr12:37922720 T/C cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs6977660 0.714 rs10236607 chr7:19818620 A/G cg07541023 chr7:19748670 TWISTNB 0.4 6.02 0.31 4.46e-9 Thyroid stimulating hormone; LIHC cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.643 rs552882 chr2:219401726 G/A cg17980119 chr2:219472607 PLCD4 0.35 6.02 0.31 4.62e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs1559088 0.947 rs10403238 chr19:33552405 A/G cg17764715 chr19:33622953 WDR88 0.41 5.74 0.3 2.09e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2072499 0.833 rs2842870 chr1:156200671 T/C cg24450063 chr1:156163899 SLC25A44 0.73 12.47 0.56 1.11e-29 Testicular germ cell tumor; LIHC cis rs427394 0.802 rs274712 chr5:6723950 G/A cg10857441 chr5:6722123 POLS -0.36 -6.3 -0.32 8.93e-10 Menopause (age at onset); LIHC trans rs12478296 1.000 rs60533128 chr2:243028088 A/G cg01596870 chr19:55963115 NA -0.62 -7.22 -0.36 3.4e-12 Obesity-related traits; LIHC cis rs9473924 0.542 rs9296645 chr6:50831194 A/G cg14470998 chr6:50812995 TFAP2B 0.89 10.14 0.48 2.75e-21 Body mass index; LIHC cis rs1552244 0.572 rs66514627 chr3:10166632 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs17094222 0.812 rs1891914 chr10:102434048 T/A cg26540559 chr10:102447443 NA 0.33 6.28 0.32 1.02e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg08888203 chr3:10149979 C3orf24 0.55 6.35 0.32 6.76e-10 Alzheimer's disease; LIHC trans rs1814175 0.645 rs4598671 chr11:50003191 C/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs8180040 0.577 rs12493425 chr3:47176946 T/G cg16586182 chr3:47516702 SCAP -0.48 -8.47 -0.42 7.37e-16 Colorectal cancer; LIHC cis rs2607426 0.681 rs2254338 chr19:41255603 G/A cg20631044 chr19:41255890 C19orf54;SNRPA -0.56 -6.64 -0.34 1.21e-10 Blood protein levels; LIHC cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg08132940 chr7:1081526 C7orf50 -0.79 -6.71 -0.34 8.26e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9733 0.596 rs56058687 chr1:150635066 C/T cg18016565 chr1:150552671 MCL1 0.59 11.54 0.53 2.98e-26 Tonsillectomy; LIHC cis rs9513627 0.915 rs73556174 chr13:100121797 T/C cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs736408 0.648 rs3774355 chr3:52817778 G/A cg18404041 chr3:52824283 ITIH1 -0.66 -10.93 -0.51 4.67e-24 Bipolar disorder; LIHC cis rs9388451 0.839 rs10457469 chr6:126083658 G/A cg05901451 chr6:126070800 HEY2 -0.76 -17.73 -0.69 2.51e-50 Brugada syndrome; LIHC cis rs9611565 0.729 rs12165508 chr22:41819960 T/C cg03806693 chr22:41940476 POLR3H 0.55 7.34 0.37 1.53e-12 Vitiligo; LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg21747090 chr2:27597821 SNX17 -0.44 -6.52 -0.33 2.46e-10 Total body bone mineral density; LIHC cis rs208520 0.690 rs7739253 chr6:66861052 A/G cg07460842 chr6:66804631 NA -0.78 -8.49 -0.42 6.5e-16 Exhaled nitric oxide output; LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg21747090 chr2:27597821 SNX17 -0.41 -6.12 -0.31 2.64e-9 Total body bone mineral density; LIHC cis rs10056811 0.538 rs2035191 chr5:74413713 T/C cg19683494 chr5:74908142 NA 0.58 7.15 0.36 5.23e-12 Coronary artery disease; LIHC cis rs4969178 0.641 rs4969141 chr17:76391653 C/T cg20026190 chr17:76395443 PGS1 0.4 5.95 0.31 6.78e-9 HDL cholesterol levels; LIHC cis rs3749237 0.537 rs4459909 chr3:49469217 T/C cg07636037 chr3:49044803 WDR6 0.53 8.12 0.4 8.59e-15 Resting heart rate; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg14601621 chr9:97848457 C9orf3 0.36 6.1 0.31 2.84e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg18305652 chr10:134549665 INPP5A 0.43 6.21 0.32 1.51e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20203792 chr4:20701925 PACRGL 0.42 6.76 0.34 5.8e-11 Cognitive function; LIHC cis rs10464366 0.544 rs12701697 chr7:39182165 C/T cg20302533 chr7:39170763 POU6F2 0.38 7.02 0.35 1.22e-11 IgG glycosylation; LIHC cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg25894440 chr7:65020034 NA 0.54 6.22 0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs8062405 0.755 rs4787457 chr16:28555400 A/G cg07451762 chr16:28383216 NA 0.39 7.05 0.36 9.95e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9486719 0.749 rs1009596 chr6:96843688 A/G cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs6500602 1.000 rs7204827 chr16:4467533 C/T cg08645402 chr16:4508243 NA 0.4 7.33 0.37 1.69e-12 Schizophrenia; LIHC cis rs765787 0.530 rs2554453 chr15:45522107 A/G cg25801113 chr15:45476975 SHF 0.38 6.51 0.33 2.69e-10 Uric acid levels; LIHC cis rs5769707 0.777 rs8141219 chr22:50044546 A/G cg07959070 chr22:50026188 C22orf34 -0.35 -8.83 -0.43 5.38e-17 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2797160 0.904 rs2326292 chr6:125999674 G/A cg05901451 chr6:126070800 HEY2 -0.47 -7.75 -0.39 1.03e-13 Endometrial cancer; LIHC trans rs6058796 1.000 rs6058796 chr20:31255829 C/T cg02600331 chr11:130417168 NA 0.36 7.84 0.39 5.92e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC trans rs10411161 0.702 rs10423838 chr19:52387283 C/T cg22319618 chr22:45562946 NUP50 -0.61 -8.37 -0.41 1.47e-15 Breast cancer; LIHC cis rs6754311 0.773 rs1435576 chr2:136641882 A/T cg07305463 chr2:136567211 LCT -0.4 -7.6 -0.38 2.8e-13 Mosquito bite size; LIHC cis rs4713118 0.662 rs9468277 chr6:28028390 C/A cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC trans rs637571 0.607 rs574586 chr11:65697083 G/A cg17712092 chr4:129076599 LARP1B 0.81 14.08 0.61 7.7e-36 Eosinophil percentage of white cells; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06380923 chr16:2273553 E4F1 0.44 6.1 0.31 2.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6546550 0.904 rs3771537 chr2:70038792 A/C cg02498382 chr2:70120550 SNRNP27 -0.38 -6.26 -0.32 1.16e-9 Prevalent atrial fibrillation; LIHC cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.82 -0.39 6.62e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs6840360 0.653 rs13136369 chr4:152731283 T/G cg22705602 chr4:152727874 NA 0.3 6.3 0.32 9.02e-10 Intelligence (multi-trait analysis); LIHC cis rs2066819 1.000 rs2695788 chr12:56697110 G/A cg26714650 chr12:56694279 CS 1.22 14.7 0.62 3.05e-38 Psoriasis vulgaris; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs12980942 0.810 rs8105901 chr19:41792092 T/A cg25627403 chr19:41769009 HNRNPUL1 0.57 6.83 0.35 3.95e-11 Coronary artery disease; LIHC cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg19318889 chr4:1322082 MAEA 0.39 6.35 0.32 6.73e-10 Obesity-related traits; LIHC cis rs62380364 0.507 rs34321 chr5:88020319 C/G cg22951263 chr5:87985283 NA -0.39 -6.72 -0.34 7.43e-11 Intelligence (multi-trait analysis); LIHC cis rs4699052 1.000 rs7661702 chr4:104140129 C/G cg16532752 chr4:104119610 CENPE -0.43 -6.94 -0.35 1.98e-11 Testicular germ cell tumor; LIHC cis rs763121 0.853 rs5750622 chr22:38956464 C/G cg14440974 chr22:39074834 NA -0.43 -6.84 -0.35 3.77e-11 Menopause (age at onset); LIHC cis rs10751667 0.666 rs4072741 chr11:976565 T/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.8e-13 Alzheimer's disease (late onset); LIHC cis rs16958440 0.867 rs10083937 chr18:44695602 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg12310025 chr6:25882481 NA -0.71 -9.2 -0.45 3.59e-18 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.593 rs7299329 chr12:38447943 G/C cg26384229 chr12:38710491 ALG10B 0.62 8.62 0.42 2.45e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.57 -0.46 2.3e-19 Initial pursuit acceleration; LIHC cis rs7772486 0.727 rs12190966 chr6:146146820 T/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.93 -0.31 7.4e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4803468 0.935 rs12602 chr19:41889748 T/C cg09537434 chr19:41945824 ATP5SL -1.0 -20.15 -0.74 4.44e-60 Height; LIHC cis rs34779708 0.966 rs7070427 chr10:35485689 A/T cg03585969 chr10:35415529 CREM 0.85 12.81 0.57 6.11e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1865721 0.682 rs3745082 chr18:73142734 G/T cg26385618 chr18:73139727 C18orf62 -0.28 -7.66 -0.38 1.87e-13 Intelligence; LIHC cis rs6459788 0.720 rs6965466 chr7:157250749 G/T cg06271696 chr7:157225062 NA -0.48 -7.14 -0.36 5.52e-12 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs7726839 0.561 rs4957049 chr5:579080 C/A cg09021430 chr5:549028 NA -0.41 -8.63 -0.42 2.28e-16 Obesity-related traits; LIHC cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg09904177 chr6:26538194 HMGN4 0.57 11.28 0.52 2.58e-25 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01593421 chr7:65303149 NA 0.48 6.51 0.33 2.74e-10 Hepatitis; LIHC cis rs7647973 0.626 rs1463728 chr3:49647404 T/A cg03060546 chr3:49711283 APEH 0.61 6.87 0.35 3e-11 Menarche (age at onset); LIHC cis rs11711311 1.000 rs9827682 chr3:113450251 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.42 -0.37 9.42e-13 IgG glycosylation; LIHC cis rs13427251 0.903 rs6746402 chr2:100150443 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.61 -7.59 -0.38 3.02e-13 Chronic sinus infection; LIHC cis rs7927771 0.832 rs11605672 chr11:47413733 A/G cg20307385 chr11:47447363 PSMC3 -0.47 -6.24 -0.32 1.29e-9 Subjective well-being; LIHC cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg27572855 chr1:25598939 RHD 0.42 9.56 0.46 2.46e-19 Erythrocyte sedimentation rate; LIHC cis rs1669338 0.507 rs4685607 chr3:3179400 C/T cg16797762 chr3:3221439 CRBN 0.98 9.0 0.44 1.56e-17 White matter integrity; LIHC cis rs738322 0.554 rs6001033 chr22:38557513 T/A cg25457927 chr22:38595422 NA -0.36 -8.56 -0.42 3.75e-16 Cutaneous nevi; LIHC cis rs10791097 1.000 rs10791098 chr11:130718711 T/G cg12179176 chr11:130786555 SNX19 0.61 9.44 0.45 6.02e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs3096299 0.900 rs4785663 chr16:89434888 G/A cg02187348 chr16:89574699 SPG7 0.45 6.55 0.33 2.16e-10 Multiple myeloma (IgH translocation); LIHC cis rs1008375 1.000 rs4698198 chr4:17656536 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.86 0.3 1.08e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12477438 0.765 rs7571390 chr2:99626593 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.3 -0.41 2.41e-15 Chronic sinus infection; LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg08677398 chr8:58056175 NA 0.41 6.27 0.32 1.07e-9 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.855 rs571462 chr11:111487106 C/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs722599 0.748 rs55707505 chr14:75362552 T/C cg08847533 chr14:75593920 NEK9 -0.57 -9.32 -0.45 1.45e-18 IgG glycosylation; LIHC cis rs4629710 0.592 rs1885641 chr6:131553986 A/G cg12606694 chr6:131520996 AKAP7 0.62 7.25 0.37 2.76e-12 Multiple myeloma (IgH translocation); LIHC cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg09455208 chr3:40491958 NA -0.32 -6.25 -0.32 1.25e-9 Renal cell carcinoma; LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg02951883 chr7:2050386 MAD1L1 -0.76 -12.93 -0.57 2.03e-31 Bipolar disorder and schizophrenia; LIHC cis rs12931792 0.682 rs12373078 chr16:30187676 T/G cg17640201 chr16:30407289 ZNF48 0.39 6.45 0.33 3.84e-10 Tonsillectomy; LIHC cis rs924607 0.898 rs905193 chr5:635095 T/C cg04476341 chr5:669733 TPPP 0.39 8.78 0.43 7.81e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7208859 0.623 rs73269974 chr17:29112384 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg24514230 chr11:3688722 CHRNA10 0.42 7.07 0.36 8.57e-12 Bipolar disorder; LIHC cis rs6582630 0.559 rs12318620 chr12:38522340 T/C cg26384229 chr12:38710491 ALG10B -0.48 -6.63 -0.34 1.29e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg05890377 chr2:74357713 NA 0.62 12.71 0.57 1.37e-30 Gestational age at birth (maternal effect); LIHC cis rs7107174 0.892 rs4945273 chr11:78096977 T/C cg02023728 chr11:77925099 USP35 0.46 8.55 0.42 4.2e-16 Testicular germ cell tumor; LIHC cis rs367615 0.537 rs431669 chr5:108663115 G/A cg17395555 chr5:108820864 NA 0.3 6.41 0.33 4.79e-10 Colorectal cancer (SNP x SNP interaction); LIHC cis rs74417235 0.684 rs7723610 chr5:154053349 A/C cg19735590 chr5:154026979 NA 0.48 6.07 0.31 3.34e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs6430585 0.528 rs75753154 chr2:136665711 T/C cg15123519 chr2:136567270 LCT -0.36 -5.85 -0.3 1.14e-8 Corneal structure; LIHC cis rs651907 0.535 rs1460097 chr3:101497569 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg16606324 chr3:10149918 C3orf24 0.53 5.77 0.3 1.73e-8 Alzheimer's disease; LIHC trans rs7618501 1.000 rs2271961 chr3:49878113 C/T cg21659725 chr3:3221576 CRBN -0.96 -18.76 -0.71 1.72e-54 Intelligence (multi-trait analysis); LIHC cis rs11577318 0.853 rs11803933 chr1:26629465 G/C cg00852783 chr1:26633632 UBXN11 0.42 6.8 0.35 4.66e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs9649465 0.561 rs600081 chr7:123414591 A/T cg03229431 chr7:123269106 ASB15 0.43 9.17 0.44 4.56e-18 Migraine; LIHC cis rs10870270 1.000 rs7078692 chr10:133775370 T/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.77 -0.57 8.31e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg18225595 chr11:63971243 STIP1 0.65 8.14 0.4 7.43e-15 Mean platelet volume; LIHC cis rs3768617 0.510 rs10797835 chr1:183072908 T/C ch.1.3577855R chr1:183094577 LAMC1 0.63 11.06 0.51 1.62e-24 Fuchs's corneal dystrophy; LIHC cis rs34779708 0.966 rs12260130 chr10:35467671 C/T cg03585969 chr10:35415529 CREM 0.86 13.05 0.58 7.33e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs611744 0.647 rs628206 chr8:109247873 A/G cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs7584330 0.554 rs10208231 chr2:238433225 C/T cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.39e-9 Prostate cancer; LIHC cis rs9457247 1.000 rs376574 chr6:167389956 A/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg11890956 chr21:40555474 PSMG1 -0.47 -7.68 -0.38 1.64e-13 Cognitive function; LIHC cis rs7944584 0.610 rs2596407 chr11:47361838 A/G cg20307385 chr11:47447363 PSMC3 -0.55 -5.82 -0.3 1.35e-8 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs875971 0.862 rs13536 chr7:66019190 G/A cg18252515 chr7:66147081 NA 0.46 6.8 0.35 4.67e-11 Aortic root size; LIHC cis rs2153535 0.580 rs7745043 chr6:8513507 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.56 0.42 3.77e-16 Motion sickness; LIHC cis rs7772486 0.754 rs697053 chr6:145989807 T/C cg05347473 chr6:146136440 FBXO30 -0.36 -5.72 -0.3 2.3e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7587476 0.784 rs36086595 chr2:215680293 A/G cg04530015 chr2:215796436 ABCA12 -0.38 -6.23 -0.32 1.38e-9 Neuroblastoma; LIHC cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg03264133 chr6:25882463 NA -0.61 -8.65 -0.42 2.08e-16 Blood metabolite levels; LIHC cis rs6088580 0.634 rs6141465 chr20:32967314 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg26939375 chr7:64535504 NA 0.47 7.13 0.36 5.83e-12 Aortic root size; LIHC cis rs4888262 0.507 rs9888976 chr16:74580924 C/T cg01733217 chr16:74700730 RFWD3 0.79 15.25 0.64 2.04e-40 Testicular germ cell tumor; LIHC cis rs72781680 0.716 rs2712086 chr2:24004739 G/C cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.07e-9 Lymphocyte counts; LIHC cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg23248424 chr5:179741104 GFPT2 -0.43 -6.32 -0.32 8.05e-10 Height; LIHC cis rs796364 0.806 rs11679658 chr2:200923081 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs986417 0.901 rs1955693 chr14:61012331 T/C cg27398547 chr14:60952738 C14orf39 0.74 8.02 0.4 1.71e-14 Gut microbiota (bacterial taxa); LIHC cis rs9811920 0.609 rs4479633 chr3:99654510 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.74 -0.3 2.12e-8 Axial length; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13446235 chr16:90039146 AFG3L1;CENPBD1 0.5 6.92 0.35 2.19e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs903552 0.932 rs1587108 chr15:102006825 G/A cg25677261 chr15:102009856 PCSK6 -0.45 -6.0 -0.31 5.05e-9 Diabetic kidney disease; LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.52 0.77 1.68e-69 Height; LIHC trans rs11088226 0.681 rs2833902 chr21:33940458 A/G cg09050820 chr6:167586206 TCP10L2 0.87 13.61 0.59 5.27e-34 Gastritis; LIHC cis rs2153535 0.546 rs1335640 chr6:8485325 A/C cg21535247 chr6:8435926 SLC35B3 0.6 7.94 0.39 2.89e-14 Motion sickness; LIHC cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg08132940 chr7:1081526 C7orf50 -0.83 -6.87 -0.35 3.01e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2404602 0.716 rs17460201 chr15:76673627 C/T cg03037974 chr15:76606532 NA -0.79 -16.53 -0.67 1.6e-45 Blood metabolite levels; LIHC trans rs1005277 0.579 rs2504140 chr10:38387579 T/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1348850 0.597 rs13014417 chr2:178417835 T/G cg27490568 chr2:178487706 NA 0.81 9.58 0.46 2.01e-19 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7264396 0.561 rs6142470 chr20:34570579 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -7.99 -0.4 2.12e-14 Total cholesterol levels; LIHC cis rs7100689 0.753 rs1361458 chr10:82090339 A/T cg01528321 chr10:82214614 TSPAN14 0.87 12.03 0.55 5.07e-28 Post bronchodilator FEV1; LIHC cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg14983838 chr19:29218262 NA 0.37 6.44 0.33 3.95e-10 Methadone dose in opioid dependence; LIHC cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg20607798 chr8:58055168 NA 0.67 8.37 0.41 1.5e-15 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.579 rs1614236 chr10:38502996 C/T cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.86 -0.3 1.06e-8 Extrinsic epigenetic age acceleration; LIHC cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg16405210 chr4:1374714 KIAA1530 -0.44 -6.67 -0.34 1.01e-10 Obesity-related traits; LIHC trans rs9929218 0.529 rs11640736 chr16:68738324 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.85 18.04 0.7 1.42e-51 Colorectal cancer; LIHC cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg12463550 chr7:65579703 CRCP 0.7 7.18 0.36 4.49e-12 Diabetic kidney disease; LIHC cis rs172166 0.694 rs9295760 chr6:28147385 G/A cg23485639 chr6:28045615 ZNF165 0.38 5.95 0.31 6.46e-9 Cardiac Troponin-T levels; LIHC cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 7.26 0.37 2.61e-12 Colonoscopy-negative controls vs population controls; LIHC trans rs2235573 0.551 rs139895 chr22:38397034 A/G cg19894588 chr14:64061835 NA -0.46 -6.1 -0.31 2.91e-9 Glioblastoma;Glioma; LIHC cis rs6951245 0.554 rs11544331 chr7:1131411 C/T cg22907277 chr7:1156413 C7orf50 0.91 8.56 0.42 3.82e-16 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs908922 0.676 rs908927 chr1:152513338 C/G cg23254163 chr1:152506842 NA 0.23 5.96 0.31 6.15e-9 Hair morphology; LIHC cis rs3770081 1.000 rs12328085 chr2:86262009 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -9.3 -0.45 1.76e-18 Facial emotion recognition (sad faces); LIHC cis rs6089584 1.000 rs6142910 chr20:60562181 C/A cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs11098499 0.754 rs1546503 chr4:120241167 T/C cg09307838 chr4:120376055 NA 0.71 11.17 0.52 6.58e-25 Corneal astigmatism; LIHC cis rs950776 0.518 rs12903129 chr15:78819606 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.68 0.34 9.78e-11 Sudden cardiac arrest; LIHC cis rs881375 0.678 rs7021049 chr9:123683982 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.74 0.34 6.66e-11 Rheumatoid arthritis; LIHC cis rs10479542 0.701 rs10479541 chr5:178981003 G/C cg09060608 chr5:178986726 RUFY1 0.38 5.79 0.3 1.59e-8 Lung cancer; LIHC cis rs2242116 0.796 rs7645278 chr3:46974100 A/C cg27129171 chr3:47204927 SETD2 0.56 8.94 0.44 2.52e-17 Birth weight; LIHC trans rs9388451 0.807 rs1268070 chr6:126041164 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.5 -7.4 -0.37 1.03e-12 Brugada syndrome; LIHC cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg10295955 chr4:187884368 NA -0.96 -22.55 -0.77 1.2e-69 Lobe attachment (rater-scored or self-reported); LIHC cis rs921968 0.643 rs611203 chr2:219472325 G/A cg02985541 chr2:219472218 PLCD4 0.45 8.47 0.42 7.32e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs9905704 0.624 rs4932691 chr17:57094617 T/C cg05425664 chr17:57184151 TRIM37 0.41 5.76 0.3 1.88e-8 Testicular germ cell tumor; LIHC cis rs1799949 0.965 rs799912 chr17:41257134 T/C cg05368731 chr17:41323189 NBR1 0.69 11.51 0.53 4.06e-26 Menopause (age at onset); LIHC cis rs738322 0.726 rs5750561 chr22:38595260 A/T cg25457927 chr22:38595422 NA 0.44 11.32 0.52 1.95e-25 Cutaneous nevi; LIHC cis rs1799949 0.965 rs7223952 chr17:41194885 T/C cg23758822 chr17:41437982 NA 0.89 16.12 0.66 7.14e-44 Menopause (age at onset); LIHC cis rs9457247 1.000 rs393727 chr6:167398632 T/A cg12798992 chr6:167411361 FGFR1OP 0.6 10.15 0.48 2.49e-21 Crohn's disease; LIHC trans rs5756813 0.635 rs12160750 chr22:38199054 A/G cg19894588 chr14:64061835 NA -0.68 -10.12 -0.48 3.18e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.8 -0.57 6.21e-31 Alzheimer's disease; LIHC cis rs8062405 0.755 rs111693583 chr16:28583610 C/T cg00204512 chr16:28754710 NA 0.39 6.93 0.35 2.12e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7843479 0.965 rs11135763 chr8:21813962 A/G cg17168535 chr8:21777572 XPO7 0.41 6.41 0.33 4.8e-10 Mean corpuscular volume; LIHC cis rs9388451 0.626 rs3734637 chr6:126081319 G/T cg06289844 chr6:126071538 HEY2 0.34 5.88 0.3 9.94e-9 Brugada syndrome; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs9790314 0.967 rs6762645 chr3:160948349 T/G cg03342759 chr3:160939853 NMD3 -0.74 -9.03 -0.44 1.25e-17 Morning vs. evening chronotype; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08722104 chr11:47448306 PSMC3 0.45 7.11 0.36 6.98e-12 Cognitive function; LIHC trans rs1005277 0.557 rs176887 chr10:38406094 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2984613 1 rs2984613 chr1:156197380 C/T cg25208724 chr1:156163844 SLC25A44 0.58 9.68 0.46 9.37e-20 Intracerebral hemorrhage;White matter hyperintensity burden; LIHC cis rs2067615 0.524 rs9971765 chr12:107092299 G/A cg15890332 chr12:107067104 RFX4 0.26 6.15 0.32 2.14e-9 Heart rate; LIHC cis rs7953249 0.502 rs1169294 chr12:121426594 G/A cg02403541 chr12:121454288 C12orf43 0.46 7.43 0.37 8.61e-13 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs17253792 0.822 rs17746033 chr14:56061837 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs6138458 1.000 rs227615 chr20:24908721 T/C cg26195577 chr20:24973756 C20orf3 1.1 13.84 0.6 6.94e-35 Blood protein levels; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg21747090 chr2:27597821 SNX17 -0.39 -5.77 -0.3 1.79e-8 Total body bone mineral density; LIHC cis rs9549367 0.707 rs9549353 chr13:113843427 G/A cg00898013 chr13:113819073 PROZ -0.48 -8.02 -0.4 1.74e-14 Platelet distribution width; LIHC cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg12310025 chr6:25882481 NA -0.45 -6.95 -0.35 1.82e-11 Height; LIHC cis rs2070488 0.965 rs4679060 chr3:38536261 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.92 -15.95 -0.65 3.35e-43 Electrocardiographic conduction measures; LIHC cis rs1580019 0.587 rs10951338 chr7:32560089 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.86 0.43 4.49e-17 Cognitive ability; LIHC cis rs1403694 0.515 rs1648722 chr3:186448989 C/T cg12454167 chr3:186435060 KNG1 0.3 7.05 0.36 1.01e-11 Blood protein levels; LIHC cis rs2836950 0.501 rs11088470 chr21:40689162 A/G cg06238570 chr21:40685208 BRWD1 -0.45 -7.42 -0.37 9.54e-13 Menarche (age at onset); LIHC cis rs7707921 1.000 rs79616997 chr5:81504600 G/T cg15871215 chr5:81402204 ATG10 -0.6 -5.95 -0.31 6.57e-9 Breast cancer; LIHC cis rs8062405 0.965 rs7359397 chr16:28885659 C/T cg07451762 chr16:28383216 NA 0.33 6.13 0.31 2.44e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3806843 0.735 rs2563314 chr5:140047289 A/G cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.32e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs60871478 0.853 rs62432864 chr7:808405 T/G cg04727924 chr7:799746 HEATR2 -0.59 -8.52 -0.42 5.21e-16 Cerebrospinal P-tau181p levels; LIHC cis rs3106136 0.649 rs11097426 chr4:95309450 G/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.85 0.3 1.13e-8 Capecitabine sensitivity; LIHC cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.99 -0.31 5.18e-9 Colorectal cancer; LIHC trans rs875971 0.571 rs160641 chr7:65577346 G/A cg26939375 chr7:64535504 NA -0.41 -6.4 -0.33 5.04e-10 Aortic root size; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg20102877 chr2:27665638 KRTCAP3 -0.44 -6.09 -0.31 3.02e-9 Total body bone mineral density; LIHC cis rs1008375 0.900 rs10019460 chr4:17686337 T/C cg16339924 chr4:17578868 LAP3 -0.48 -6.39 -0.33 5.3e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9419702 0.568 rs7093241 chr10:133556596 G/A cg04492858 chr10:133558786 NA 0.45 6.82 0.35 4.01e-11 Survival in rectal cancer; LIHC cis rs12142240 0.698 rs6695043 chr1:46844530 A/G cg14993813 chr1:46806288 NSUN4 0.67 6.28 0.32 1.01e-9 Menopause (age at onset); LIHC cis rs4665809 0.549 rs17527979 chr2:26428132 A/G cg27170947 chr2:26402098 FAM59B -0.59 -6.19 -0.32 1.76e-9 Gut microbiome composition (summer); LIHC cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs35110281 0.840 rs7276633 chr21:45078800 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.47 6.59 0.34 1.7e-10 Mean corpuscular volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26817334 chr2:119613580 NA 0.46 6.04 0.31 4.06e-9 Lung function (FEV1/FVC); LIHC cis rs72781680 1.000 rs72781654 chr2:24218099 T/C cg08917208 chr2:24149416 ATAD2B 0.59 5.94 0.31 6.94e-9 Lymphocyte counts; LIHC cis rs7116495 0.618 rs7943227 chr11:71670721 G/A cg26138937 chr11:71823887 C11orf51 -0.7 -7.08 -0.36 8.39e-12 Severe influenza A (H1N1) infection; LIHC cis rs10078 0.510 rs2278248 chr5:469570 G/T cg08916839 chr5:415575 AHRR 0.55 12.13 0.55 2.03e-28 Fat distribution (HIV); LIHC cis rs6088813 0.961 rs1886691 chr20:33986271 T/C cg14752227 chr20:34000481 UQCC -0.41 -5.88 -0.3 9.69e-9 Height; LIHC cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg13271783 chr10:134563150 INPP5A -0.56 -7.09 -0.36 7.62e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs595982 0.527 rs55706579 chr19:49382969 G/A cg15549821 chr19:49342101 PLEKHA4 -0.65 -5.97 -0.31 5.95e-9 Red cell distribution width; LIHC cis rs7772486 0.754 rs6570718 chr6:146088443 T/G cg23711669 chr6:146136114 FBXO30 -0.74 -13.29 -0.58 8.62e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs3888647 0.561 rs4758617 chr11:2995185 T/A cg25174290 chr11:3078921 CARS 0.57 8.71 0.43 1.28e-16 Type 2 diabetes; LIHC cis rs3862260 0.967 rs3862261 chr1:120160822 G/A cg16322792 chr1:120165303 ZNF697 0.46 8.45 0.42 8.77e-16 Systemic lupus erythematosus; LIHC cis rs10865541 0.902 rs12476309 chr2:3404845 C/T cg11642891 chr2:3452563 TTC15 -0.42 -6.69 -0.34 9.12e-11 Obesity-related traits; LIHC cis rs635808 0.561 rs491700 chr6:167171838 A/G cg05573767 chr6:167171394 RPS6KA2 -0.34 -7.26 -0.37 2.55e-12 Dental caries; LIHC cis rs748404 0.631 rs1133395 chr15:43650384 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.89 0.43 3.56e-17 Lung cancer; LIHC cis rs4919694 1.000 rs11191445 chr10:104651055 C/T cg04362960 chr10:104952993 NT5C2 1.12 8.77 0.43 8.35e-17 Arsenic metabolism; LIHC cis rs6456156 0.586 rs2001115 chr6:167486218 A/C cg12798992 chr6:167411361 FGFR1OP 0.44 6.65 0.34 1.13e-10 Primary biliary cholangitis; LIHC trans rs459571 1.000 rs2810489 chr9:136922700 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.56 -8.85 -0.43 4.92e-17 Platelet distribution width; LIHC cis rs941873 0.805 rs10824747 chr10:81118464 T/C cg11057378 chr10:81107060 PPIF 0.37 6.0 0.31 5.15e-9 Height; LIHC cis rs7408868 1.000 rs2074622 chr19:15277620 G/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.89 -0.3 9.39e-9 Pulse pressure; LIHC cis rs244293 0.931 rs2170942 chr17:53209515 A/C cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.44 -0.37 8.44e-13 Menarche (age at onset); LIHC cis rs12594515 0.591 rs35554150 chr15:45990298 G/A cg01629716 chr15:45996671 NA 0.55 6.35 0.32 6.98e-10 Waist circumference;Weight; LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.91 -0.3 8.3e-9 Total body bone mineral density; LIHC cis rs11112613 0.762 rs17037308 chr12:105949847 T/G cg03607813 chr12:105948248 NA 0.67 13.37 0.59 4.49e-33 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC trans rs11098499 0.739 rs4833612 chr4:120147596 A/C cg25214090 chr10:38739885 LOC399744 -0.38 -6.25 -0.32 1.22e-9 Corneal astigmatism; LIHC trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg21548813 chr6:291882 DUSP22 -0.46 -6.28 -0.32 1.02e-9 Menopause (age at onset); LIHC cis rs1395 0.744 rs62130709 chr2:27505782 C/T cg22903471 chr2:27725779 GCKR -0.43 -6.32 -0.32 7.98e-10 Blood metabolite levels; LIHC cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg14393609 chr7:65229607 NA 0.44 6.47 0.33 3.34e-10 Aortic root size; LIHC cis rs7493 0.755 rs13223537 chr7:94966167 C/T cg19678392 chr7:94953810 PON1 0.47 5.81 0.3 1.44e-8 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg08677398 chr8:58056175 NA 0.41 5.99 0.31 5.21e-9 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.686 rs1011596 chr6:146076433 A/G cg23711669 chr6:146136114 FBXO30 0.64 11.61 0.53 1.68e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2050392 0.630 rs303428 chr10:30739058 C/T cg25182066 chr10:30743637 MAP3K8 0.51 7.68 0.38 1.69e-13 Inflammatory bowel disease; LIHC cis rs13161895 0.941 rs6876648 chr5:179441842 T/C cg02702477 chr5:179499311 RNF130 -0.75 -10.33 -0.49 5.85e-22 LDL cholesterol; LIHC cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg03060546 chr3:49711283 APEH 0.4 5.99 0.31 5.39e-9 Menarche (age at onset); LIHC cis rs11711311 1.000 rs2566963 chr3:113531849 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 -0.4 -7.28 -0.37 2.29e-12 IgG glycosylation; LIHC cis rs7089973 0.604 rs58587374 chr10:116597572 A/G cg03647239 chr10:116582469 FAM160B1 0.44 6.58 0.34 1.74e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs4566357 0.615 rs4350744 chr2:227918146 A/T cg16088116 chr21:44841560 SIK1 -0.42 -6.52 -0.33 2.59e-10 Coronary artery disease; LIHC cis rs6424115 0.830 rs3123554 chr1:24196401 C/T cg15997130 chr1:24165203 NA -0.41 -8.32 -0.41 2.07e-15 Immature fraction of reticulocytes; LIHC cis rs2153535 0.580 rs6910742 chr6:8448328 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.03 0.4 1.61e-14 Motion sickness; LIHC cis rs35110281 0.782 rs1454650 chr21:45012353 C/T cg01579765 chr21:45077557 HSF2BP -0.36 -6.87 -0.35 2.97e-11 Mean corpuscular volume; LIHC cis rs507080 0.697 rs656287 chr11:118571790 A/G cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs400736 0.602 rs7553544 chr1:8165719 C/T cg25007680 chr1:8021821 PARK7 -0.49 -6.55 -0.33 2.13e-10 Response to antidepressants and depression; LIHC cis rs2576037 0.526 rs2187092 chr18:44526798 A/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.46 -6.76 -0.34 6.15e-11 Personality dimensions; LIHC cis rs4237845 0.636 rs11172371 chr12:58286188 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.51 6.83 0.35 3.84e-11 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.500 rs56404399 chr12:34543101 A/G cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs9467773 0.967 rs1056347 chr6:26527524 G/C cg09904177 chr6:26538194 HMGN4 0.67 14.0 0.6 1.66e-35 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26795923 chr22:19165960 SLC25A1 0.51 6.15 0.32 2.22e-9 Hepatitis; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg07677032 chr17:61819896 STRADA 0.44 6.42 0.33 4.45e-10 Prudent dietary pattern; LIHC cis rs2075165 0.901 rs7542798 chr1:156224304 A/G cg07234388 chr1:156261841 TMEM79 0.47 8.19 0.41 5.11e-15 Tonsillectomy; LIHC cis rs7552167 1.000 rs59960858 chr1:24519437 C/A cg01960748 chr1:24522592 NA 0.74 9.6 0.46 1.81e-19 Psoriasis vulgaris; LIHC trans rs1499614 1.000 rs2141924 chr7:66186246 C/T cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs2816062 0.813 rs742485 chr1:18900943 A/T cg18795169 chr1:18902165 NA -0.8 -17.78 -0.69 1.5e-50 Urate levels in lean individuals; LIHC cis rs2303759 0.918 rs8107548 chr19:49870643 T/C cg22307029 chr19:49891270 CCDC155 0.57 9.19 0.45 3.87e-18 Multiple sclerosis; LIHC cis rs7412746 0.611 rs12085336 chr1:150775780 A/T cg17724175 chr1:150552817 MCL1 0.45 9.26 0.45 2.34e-18 Melanoma; LIHC cis rs61990749 0.597 rs1477262 chr14:78226653 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.6 9.92 0.47 1.54e-20 Fibroblast growth factor basic levels; LIHC cis rs2303759 0.709 rs8102658 chr19:49828855 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.54 8.02 0.4 1.73e-14 Multiple sclerosis; LIHC cis rs12594515 1.000 rs8025258 chr15:45987554 C/A cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.71e-12 Waist circumference;Weight; LIHC cis rs933688 0.759 rs1423593 chr5:90752351 T/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.95 18.79 0.71 1.3e-54 Smoking behavior; LIHC trans rs911555 0.723 rs7149767 chr14:103863545 G/A cg17675199 chr6:35436792 RPL10A -0.4 -8.31 -0.41 2.35e-15 Intelligence (multi-trait analysis); LIHC cis rs743757 1.000 rs6446206 chr3:50455470 G/A cg08207895 chr3:50388901 TUSC4;CYB561D2 0.46 7.06 0.36 9.15e-12 Diastolic blood pressure; LIHC trans rs2727020 0.656 rs7925524 chr11:49437542 G/A cg18944383 chr4:111397179 ENPEP 0.31 7.43 0.37 8.81e-13 Coronary artery disease; LIHC cis rs10197940 0.578 rs6718653 chr2:152346118 C/A cg06191203 chr2:152266755 RIF1 -0.41 -7.15 -0.36 5.38e-12 Lung cancer; LIHC trans rs1814175 0.645 rs599890 chr11:49711718 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.94 0.35 1.96e-11 Height; LIHC cis rs709400 0.604 rs7158144 chr14:103887615 A/G cg26031613 chr14:104095156 KLC1 0.79 10.32 0.49 6.46e-22 Body mass index; LIHC cis rs75908454 1.000 rs79744616 chr6:169827524 T/G cg19338460 chr6:170058176 WDR27 -0.87 -7.81 -0.39 7.2e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs1494950 0.744 rs4367169 chr4:15029803 C/T cg12377275 chr4:15005593 CPEB2 0.85 7.46 0.37 7.2e-13 Political ideology; LIHC trans rs4332037 0.523 rs11770148 chr7:1899447 A/G cg11693508 chr17:37793320 STARD3 0.66 6.35 0.32 6.81e-10 Bipolar disorder; LIHC cis rs8180040 0.764 rs11716539 chr3:47186503 G/T cg27129171 chr3:47204927 SETD2 0.7 12.54 0.56 6.03e-30 Colorectal cancer; LIHC cis rs11190604 1.000 rs9419897 chr10:102246125 T/C cg07080220 chr10:102295463 HIF1AN 0.51 7.22 0.36 3.35e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1371867 0.875 rs1612773 chr8:101337818 G/C cg06636551 chr8:101224915 SPAG1 -0.47 -8.33 -0.41 2e-15 Atrioventricular conduction; LIHC cis rs7918232 0.941 rs7907988 chr10:27444344 T/G cg14442939 chr10:27389572 ANKRD26 0.69 6.74 0.34 6.73e-11 Breast cancer; LIHC cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg06634786 chr22:41940651 POLR3H 0.83 9.1 0.44 7.39e-18 Vitiligo; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg13409248 chr3:40428643 ENTPD3 0.48 8.18 0.4 5.67e-15 Renal cell carcinoma; LIHC cis rs12701220 0.894 rs13224488 chr7:1052353 C/A cg04498913 chr7:1135747 C7orf50 0.37 5.73 0.3 2.19e-8 Bronchopulmonary dysplasia; LIHC cis rs10751667 0.621 rs10794353 chr11:948740 A/G cg10932868 chr11:921992 NA 0.38 7.14 0.36 5.52e-12 Alzheimer's disease (late onset); LIHC cis rs7927592 0.913 rs3824850 chr11:68341873 A/G cg16797656 chr11:68205561 LRP5 0.5 7.8 0.39 7.44e-14 Total body bone mineral density; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04961397 chr16:30990708 SETD1A -0.43 -6.27 -0.32 1.12e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs16958440 0.867 rs57744138 chr18:44700482 A/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03122602 chr16:89799836 ZNF276 -0.44 -6.89 -0.35 2.75e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.95 0.57 1.78e-31 Prudent dietary pattern; LIHC cis rs9309473 0.848 rs17009159 chr2:73797762 A/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs2832191 1.000 rs8131214 chr21:30483386 T/G cg08807101 chr21:30365312 RNF160 -0.59 -9.28 -0.45 2.02e-18 Dental caries; LIHC cis rs10078 0.515 rs6872510 chr5:481610 T/C cg26072250 chr5:443457 EXOC3;C5orf55 0.69 8.9 0.43 3.25e-17 Fat distribution (HIV); LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg22528358 chr1:107598549 PRMT6 0.68 11.4 0.52 9.54e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2777491 0.957 rs7163788 chr15:41704789 A/G cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.54 -0.46 2.88e-19 Ulcerative colitis; LIHC cis rs7520050 0.898 rs34175029 chr1:46483871 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.83 0.3 1.31e-8 Red blood cell count;Reticulocyte count; LIHC cis rs6942756 0.806 rs7788327 chr7:128986519 C/T cg02491457 chr7:128862824 NA -0.53 -8.04 -0.4 1.52e-14 White matter hyperintensity burden; LIHC cis rs9790314 0.934 rs465985 chr3:161098552 T/C cg03342759 chr3:160939853 NMD3 -0.71 -8.31 -0.41 2.31e-15 Morning vs. evening chronotype; LIHC cis rs2839186 0.605 rs2839170 chr21:47671305 A/G cg12516959 chr21:47718080 NA -0.39 -6.22 -0.32 1.47e-9 Testicular germ cell tumor; LIHC cis rs7633770 0.805 rs11710264 chr3:46661579 T/C cg11219411 chr3:46661640 NA 0.53 9.43 0.45 6.42e-19 Coronary artery disease; LIHC cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg12463550 chr7:65579703 CRCP 0.67 6.78 0.34 5.25e-11 Diabetic kidney disease; LIHC cis rs1403694 0.515 rs5030058 chr3:186452415 T/G cg12454167 chr3:186435060 KNG1 0.32 7.68 0.38 1.73e-13 Blood protein levels; LIHC cis rs6912958 0.667 rs7746545 chr6:88090225 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.56 10.17 0.48 2.1e-21 Monocyte percentage of white cells; LIHC cis rs6547741 0.717 rs2178197 chr2:27860551 C/T cg27432699 chr2:27873401 GPN1 0.86 15.12 0.63 6.29e-40 Oral cavity cancer; LIHC cis rs2439831 0.571 rs2470121 chr15:43937618 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.18 0.44 4.05e-18 Lung cancer in ever smokers; LIHC cis rs11711311 1.000 rs4362695 chr3:113534856 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.37 6.72 0.34 7.42e-11 IgG glycosylation; LIHC cis rs9916302 0.904 rs4511574 chr17:37532916 A/G cg07936489 chr17:37558343 FBXL20 -0.8 -12.54 -0.56 6.12e-30 Glomerular filtration rate (creatinine); LIHC cis rs2075371 0.966 rs2544224 chr7:133995832 A/G cg20476274 chr7:133979776 SLC35B4 0.74 12.13 0.55 2.1e-28 Mean platelet volume; LIHC cis rs3780486 0.846 rs6476402 chr9:33148552 G/A cg13443165 chr9:33130375 B4GALT1 -0.34 -5.94 -0.31 7.03e-9 IgG glycosylation; LIHC cis rs7666738 0.830 rs13124904 chr4:98856973 T/C cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs2073300 0.609 rs2281428 chr20:23400050 C/T cg12062639 chr20:23401060 NAPB 1.05 14.07 0.61 8.82e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11122272 0.735 rs973254 chr1:231521149 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.93 -0.51 4.89e-24 Hemoglobin concentration; LIHC cis rs13108904 0.517 rs13134568 chr4:1334289 G/A cg00684032 chr4:1343700 KIAA1530 0.58 8.6 0.42 2.89e-16 Obesity-related traits; LIHC trans rs17685 0.753 rs13240404 chr7:75675719 C/T cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.75 -0.71 1.96e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg13395646 chr4:1353034 KIAA1530 -0.42 -6.01 -0.31 4.69e-9 Longevity; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg18954051 chr12:66554863 TMBIM4 0.54 6.17 0.32 1.92e-9 Mean platelet volume; LIHC cis rs6545883 0.931 rs12713438 chr2:61725501 G/A cg14146966 chr2:61757674 XPO1 0.49 8.61 0.42 2.74e-16 Tuberculosis; LIHC cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.59 0.62 8.17e-38 Prudent dietary pattern; LIHC cis rs11098499 0.874 rs9995277 chr4:120108603 G/A cg09307838 chr4:120376055 NA 0.53 7.75 0.39 1.08e-13 Corneal astigmatism; LIHC cis rs2073300 0.609 rs77673953 chr20:23398794 G/C cg16736954 chr20:23401023 NAPB 0.71 8.5 0.42 5.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs57590327 0.528 rs2229519 chr3:81698130 T/C cg07356753 chr3:81810745 GBE1 -0.54 -8.13 -0.4 7.92e-15 Extraversion; LIHC cis rs937213 0.676 rs8042456 chr15:40290476 G/T cg20255370 chr15:40268687 EIF2AK4 -0.44 -6.79 -0.34 5.07e-11 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs6088590 0.735 rs6060001 chr20:33294353 C/T cg06115741 chr20:33292138 TP53INP2 -0.41 -6.04 -0.31 3.95e-9 Coronary artery disease; LIHC cis rs8114671 0.562 rs4911163 chr20:33470694 C/T cg07148914 chr20:33460835 GGT7 0.63 9.57 0.46 2.29e-19 Height; LIHC cis rs11997175 0.766 rs4273817 chr8:33702686 C/T cg04338863 chr8:33670619 NA 0.31 5.8 0.3 1.49e-8 Body mass index; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.79 0.62 1.31e-38 Prudent dietary pattern; LIHC cis rs9914988 0.943 rs3181215 chr17:27077331 C/T cg20469991 chr17:27169893 C17orf63 0.51 6.14 0.32 2.29e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg27170947 chr2:26402098 FAM59B 0.65 7.73 0.39 1.23e-13 Gut microbiome composition (summer); LIHC cis rs5758659 0.845 rs5758645 chr22:42598951 T/G cg19513890 chr22:42538836 CYP2D7P1 -0.4 -7.69 -0.38 1.59e-13 Cognitive function; LIHC cis rs1823913 0.599 rs1378156 chr2:192137192 A/T cg12404831 chr2:192114017 MYO1B -0.28 -5.72 -0.3 2.31e-8 Obesity-related traits; LIHC cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg14416726 chr6:151773293 C6orf211;RMND1 0.6 8.68 0.42 1.61e-16 Menarche (age at onset); LIHC cis rs7615952 0.576 rs4646748 chr3:125826329 G/A cg05084668 chr3:125655381 ALG1L -0.41 -6.34 -0.32 7.39e-10 Blood pressure (smoking interaction); LIHC cis rs1801251 0.963 rs35395584 chr2:233573698 G/C cg25237894 chr2:233734115 C2orf82 0.57 11.03 0.51 2.07e-24 Coronary artery disease; LIHC cis rs7178375 1.000 rs7178375 chr15:31215935 C/T cg19680485 chr15:31195859 MTMR15 -0.55 -5.9 -0.3 8.62e-9 Hypertriglyceridemia; LIHC cis rs7089973 0.584 rs6585300 chr10:116639889 A/C cg23260525 chr10:116636907 FAM160B1 0.4 7.75 0.39 1.06e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4665809 1.000 rs4233710 chr2:26291565 G/A cg04944784 chr2:26401820 FAM59B -0.71 -8.97 -0.44 1.97e-17 Gut microbiome composition (summer); LIHC trans rs783540 0.967 rs2870966 chr15:83295244 G/A cg18393722 chr15:85113863 UBE2QP1 -0.37 -6.34 -0.32 7.22e-10 Schizophrenia; LIHC cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg19318889 chr4:1322082 MAEA 0.47 6.51 0.33 2.69e-10 Obesity-related traits; LIHC cis rs2404602 0.716 rs12441550 chr15:76863682 A/T cg03037974 chr15:76606532 NA 0.74 14.47 0.62 2.32e-37 Blood metabolite levels; LIHC cis rs2404602 0.598 rs71405204 chr15:76635305 C/G cg23625390 chr15:77176239 SCAPER -0.45 -6.86 -0.35 3.14e-11 Blood metabolite levels; LIHC cis rs798554 0.679 rs2533877 chr7:2882421 G/A cg13628971 chr7:2884303 GNA12 0.59 9.9 0.47 1.71e-20 Height; LIHC cis rs763121 0.853 rs7289577 chr22:39042214 C/G cg14440974 chr22:39074834 NA -0.42 -6.72 -0.34 7.42e-11 Menopause (age at onset); LIHC cis rs1707322 0.752 rs7529699 chr1:46134634 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.57 0.38 3.45e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.579 rs1780115 chr10:38524773 C/T cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs6089829 0.962 rs3746749 chr20:61667333 T/C cg08564027 chr20:61660810 NA 0.4 7.6 0.38 2.86e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs3008870 1.000 rs2985824 chr1:67410171 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.57 -0.67 1.08e-45 Lymphocyte percentage of white cells; LIHC cis rs7662987 0.517 rs3018047 chr4:100014510 C/T cg12011299 chr4:100065546 ADH4 -0.54 -9.15 -0.44 5.06e-18 Smoking initiation; LIHC cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg13393036 chr8:95962371 TP53INP1 -0.45 -10.9 -0.51 6.28e-24 Type 2 diabetes; LIHC cis rs7106204 1.000 rs7110656 chr11:24216034 G/T ch.11.24196551F chr11:24239977 NA 0.68 6.83 0.35 3.89e-11 Response to Homoharringtonine (cytotoxicity); LIHC cis rs12931792 0.782 rs6565176 chr16:30174926 T/C cg17640201 chr16:30407289 ZNF48 0.47 7.26 0.37 2.66e-12 Tonsillectomy; LIHC cis rs11971779 0.715 rs10085527 chr7:139064360 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs7726839 0.540 rs3749618 chr5:602650 A/G cg09021430 chr5:549028 NA -0.43 -8.64 -0.42 2.2e-16 Obesity-related traits; LIHC cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.08 11.64 0.53 1.34e-26 Platelet count; LIHC cis rs9303280 0.806 rs12941333 chr17:38040534 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.72 0.3 2.27e-8 Self-reported allergy; LIHC cis rs600806 0.888 rs4603158 chr1:109879549 C/T cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.8 -0.39 7.78e-14 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg16606324 chr3:10149918 C3orf24 0.53 5.77 0.3 1.73e-8 Alzheimer's disease; LIHC cis rs1008375 0.931 rs4479701 chr4:17571496 G/A cg16339924 chr4:17578868 LAP3 0.43 5.74 0.3 2.07e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg08280861 chr8:58055591 NA 0.52 6.04 0.31 3.92e-9 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.648 rs6467852 chr7:139112591 A/C cg07862535 chr7:139043722 LUC7L2 0.59 10.29 0.49 8.39e-22 Diisocyanate-induced asthma; LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg24209194 chr3:40518798 ZNF619 -0.64 -9.72 -0.47 6.96e-20 Renal cell carcinoma; LIHC cis rs1697139 0.935 rs1627990 chr5:66513326 C/T cg16691251 chr5:66510806 NA 0.48 6.82 0.35 4.24e-11 Breast cancer; LIHC cis rs17376456 0.825 rs10061377 chr5:93174513 T/C cg25358565 chr5:93447407 FAM172A 1.06 9.36 0.45 1.06e-18 Diabetic retinopathy; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10705386 chr10:69644512 SIRT1 -0.54 -6.22 -0.32 1.43e-9 Systolic blood pressure; LIHC cis rs600806 0.850 rs2140924 chr1:109935775 A/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.92 -0.3 7.87e-9 Intelligence (multi-trait analysis); LIHC cis rs2479724 0.901 rs6458244 chr6:41790455 C/T cg17623882 chr6:41773611 USP49 0.57 9.05 0.44 1.11e-17 Menarche (age at onset); LIHC cis rs9300255 0.569 rs1790115 chr12:123620270 C/G cg00376283 chr12:123451042 ABCB9 0.58 6.44 0.33 4.09e-10 Neutrophil percentage of white cells; LIHC cis rs7208859 0.623 rs11657662 chr17:29076347 A/G cg13385521 chr17:29058706 SUZ12P -0.79 -7.96 -0.4 2.57e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1008375 1.000 rs13106338 chr4:17676871 G/T cg02297831 chr4:17616191 MED28 -0.41 -5.9 -0.3 8.98e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10492096 1.000 rs12427239 chr12:6590626 C/T cg13857086 chr12:6580257 VAMP1 0.57 5.99 0.31 5.3300000000000004e-09 Hip geometry; LIHC cis rs2070488 0.775 rs2300669 chr3:38541318 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.73 -12.28 -0.55 5.55e-29 Electrocardiographic conduction measures; LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.86 -0.3 1.08e-8 Total body bone mineral density; LIHC cis rs8072100 0.754 rs8081717 chr17:45653921 T/A cg08085267 chr17:45401833 C17orf57 0.57 8.51 0.42 5.71e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7264396 0.836 rs6120995 chr20:34185726 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -8.65 -0.42 1.99e-16 Total cholesterol levels; LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg16070018 chr6:26224392 HIST1H3E 0.59 7.45 0.37 7.55e-13 Gout;Renal underexcretion gout; LIHC cis rs12464483 0.524 rs2593470 chr2:30887402 G/T cg17749961 chr2:30669863 LCLAT1 0.47 6.01 0.31 4.68e-9 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.54 0.33 2.22e-10 Bipolar disorder; LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg06873352 chr17:61820015 STRADA 0.74 13.21 0.58 1.74e-32 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg19723775 chr5:179050963 HNRNPH1 0.45 6.97 0.35 1.65e-11 Lung cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02056921 chr1:901892 PLEKHN1 0.39 6.42 0.33 4.52e-10 Cognitive function; LIHC cis rs7078219 0.523 rs10883366 chr10:101287785 G/A cg06854084 chr10:101292507 NKX2-3 -0.32 -5.89 -0.3 9.19e-9 Dental caries; LIHC cis rs477692 0.685 rs3852507 chr10:131399616 G/T cg05714579 chr10:131428358 MGMT -0.46 -7.7 -0.38 1.46e-13 Response to temozolomide; LIHC cis rs7927771 0.864 rs55927797 chr11:47446292 A/T cg20135002 chr11:47629003 NA -0.57 -9.61 -0.46 1.68e-19 Subjective well-being; LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg00280220 chr17:61926910 NA 0.42 6.83 0.35 3.82e-11 Prudent dietary pattern; LIHC trans rs4927850 0.957 rs4927851 chr3:195751853 A/G cg16724585 chr3:197361211 NA -0.46 -6.4 -0.33 5.25e-10 Pancreatic cancer; LIHC cis rs7216064 1.000 rs7210027 chr17:65977053 C/T cg12091567 chr17:66097778 LOC651250 0.7 9.86 0.47 2.48e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg04025307 chr7:1156635 C7orf50 0.55 9.15 0.44 5.17e-18 Longevity;Endometriosis; LIHC cis rs11122272 0.735 rs2244986 chr1:231537452 C/T cg06096015 chr1:231504339 EGLN1 0.48 8.99 0.44 1.69e-17 Hemoglobin concentration; LIHC cis rs1057239 0.510 rs3766694 chr1:175143207 T/C cg17845761 chr1:175162550 KIAA0040 -0.31 -5.81 -0.3 1.45e-8 Diastolic blood pressure; LIHC cis rs4319547 0.956 rs9988963 chr12:122991478 C/G cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.09 -0.4 1.03e-14 Body mass index; LIHC cis rs1552244 0.882 rs13074282 chr3:10024699 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs734999 0.566 rs10797435 chr1:2534801 G/C cg18854424 chr1:2615690 NA 0.32 6.99 0.35 1.44e-11 Ulcerative colitis; LIHC cis rs11690935 0.959 rs2674484 chr2:172574612 G/A cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.79 -0.69 1.42e-50 Schizophrenia; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg11509341 chr2:75787820 FAM176A -0.37 -6.13 -0.31 2.46e-9 Triglycerides; LIHC cis rs1577917 1.000 rs12661204 chr6:86678586 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.05 -0.48 5.62e-21 Response to antipsychotic treatment; LIHC cis rs10504229 0.679 rs73681882 chr8:58030038 A/G cg20607798 chr8:58055168 NA 0.46 6.71 0.34 7.96e-11 Developmental language disorder (linguistic errors); LIHC cis rs539514 0.690 rs1924214 chr13:76317632 A/G cg04757411 chr13:76259545 LMO7 -0.46 -8.21 -0.41 4.48e-15 Type 1 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24541279 chr10:71993373 PPA1 0.46 6.24 0.32 1.27e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6964587 0.967 rs10279210 chr7:91616891 G/A cg17063962 chr7:91808500 NA 1.03 20.75 0.75 1.71e-62 Breast cancer; LIHC trans rs11098499 0.913 rs10010696 chr4:120164303 T/C cg25214090 chr10:38739885 LOC399744 0.52 7.96 0.4 2.5e-14 Corneal astigmatism; LIHC cis rs12579753 1.000 rs12366580 chr12:82222784 G/A cg07988820 chr12:82153109 PPFIA2 -0.48 -5.84 -0.3 1.23e-8 Resting heart rate; LIHC cis rs7666738 0.962 rs13147921 chr4:99069296 C/G cg05340658 chr4:99064831 C4orf37 0.68 10.95 0.51 4.04e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs2842992 0.830 rs2758312 chr6:160153452 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.71 12.5 0.56 8.95e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs4423214 1.000 rs4944946 chr11:71159429 G/A cg05163923 chr11:71159392 DHCR7 0.97 15.12 0.63 6.35e-40 Vitamin D levels; LIHC cis rs28374715 0.578 rs17730589 chr15:41600878 T/C cg18705301 chr15:41695430 NDUFAF1 -1.22 -16.58 -0.67 9.99e-46 Ulcerative colitis; LIHC cis rs3096299 0.781 rs3102381 chr16:89409720 G/C cg06640241 chr16:89574553 SPG7 0.51 7.62 0.38 2.5e-13 Multiple myeloma (IgH translocation); LIHC cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg27572855 chr1:25598939 RHD -0.37 -7.89 -0.39 4.16e-14 Erythrocyte sedimentation rate; LIHC cis rs10463316 0.894 rs7727770 chr5:150767116 G/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.07e-10 Metabolite levels (Pyroglutamine); LIHC cis rs3106136 0.678 rs7675615 chr4:95295352 T/G cg11021082 chr4:95130006 SMARCAD1 0.35 6.0 0.31 5.07e-9 Capecitabine sensitivity; LIHC cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg08048268 chr3:133502702 NA -0.4 -5.95 -0.31 6.68e-9 Iron status biomarkers; LIHC cis rs2274273 0.805 rs28612464 chr14:55816411 T/C cg01864836 chr14:55583639 NA -0.37 -6.59 -0.34 1.66e-10 Protein biomarker; LIHC cis rs4319547 0.695 rs4758662 chr12:122924778 G/A cg23029597 chr12:123009494 RSRC2 -0.52 -7.32 -0.37 1.73e-12 Body mass index; LIHC cis rs6088590 1.000 rs2180276 chr20:33360785 T/A cg06115741 chr20:33292138 TP53INP2 0.59 8.52 0.42 5.05e-16 Coronary artery disease; LIHC trans rs9217 1.000 rs11658168 chr17:7406134 C/T cg08566640 chr11:64091735 NA -0.61 -10.1 -0.48 3.57e-21 Height; LIHC cis rs611744 0.967 rs660065 chr8:109191932 G/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg13395646 chr4:1353034 KIAA1530 -0.45 -6.61 -0.34 1.44e-10 Longevity; LIHC cis rs921968 0.541 rs17572485 chr2:219296545 C/T cg02985541 chr2:219472218 PLCD4 -0.41 -6.64 -0.34 1.24e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7923837 0.663 rs7903302 chr10:94429511 T/C cg25506282 chr10:94462361 NA 0.45 7.77 0.39 9.38e-14 Body mass index;Multiple sclerosis; LIHC cis rs2108622 0.559 rs7252638 chr19:15981025 G/C cg13772218 chr19:15982569 NA 0.37 7.83 0.39 6.2e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02593601 chr10:17707418 STAM 0.36 6.24 0.32 1.27e-9 Hepatitis; LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs6582630 0.638 rs12425379 chr12:38523705 G/A cg26384229 chr12:38710491 ALG10B -0.48 -6.56 -0.33 1.97e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs6752107 0.967 rs55835501 chr2:234157733 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.12 0.4 8.28e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7395581 0.877 rs10838691 chr11:47341729 T/C cg26139080 chr11:47293733 MADD -0.5 -8.36 -0.41 1.64e-15 HDL cholesterol; LIHC cis rs1008375 0.932 rs2302391 chr4:17660237 T/C cg16339924 chr4:17578868 LAP3 0.43 6.02 0.31 4.51e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg20891558 chr2:74357851 NA 0.62 11.25 0.52 3.39e-25 Gestational age at birth (maternal effect); LIHC trans rs1814175 0.817 rs2866545 chr11:49630824 A/C cg03929089 chr4:120376271 NA -0.89 -18.17 -0.7 4.07e-52 Height; LIHC cis rs929354 0.772 rs6971896 chr7:156978412 C/T cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg11644478 chr21:40555479 PSMG1 0.84 10.57 0.5 8.49e-23 Cognitive function; LIHC cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg04025307 chr7:1156635 C7orf50 0.57 9.28 0.45 1.95e-18 Longevity;Endometriosis; LIHC cis rs908922 0.887 rs1538084 chr1:152496012 A/C cg20991723 chr1:152506922 NA 0.39 5.92 0.3 7.98e-9 Hair morphology; LIHC cis rs7224685 0.569 rs7212168 chr17:4024640 G/A cg09695851 chr17:3907499 NA 0.63 7.27 0.37 2.41e-12 Type 2 diabetes; LIHC cis rs1577917 0.629 rs9450285 chr6:86208096 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.34 6.12 0.31 2.62e-9 Response to antipsychotic treatment; LIHC trans rs941408 1.000 rs1640271 chr19:2799979 C/T cg19676328 chr12:49525230 TUBA1B -0.37 -6.15 -0.32 2.13e-9 Total cholesterol levels; LIHC cis rs1983891 0.706 rs745548 chr6:41557117 G/T cg20194872 chr6:41519635 FOXP4 -0.4 -6.16 -0.32 2.05e-9 Prostate cancer; LIHC cis rs734999 0.588 rs2843404 chr1:2530558 T/C cg18854424 chr1:2615690 NA -0.33 -7.24 -0.36 2.95e-12 Ulcerative colitis; LIHC cis rs9399135 0.967 rs45544135 chr6:135324051 T/C cg24558204 chr6:135376177 HBS1L 0.4 6.65 0.34 1.15e-10 Red blood cell count; LIHC trans rs61931739 0.517 rs9668303 chr12:34366701 C/T cg26384229 chr12:38710491 ALG10B 0.75 9.23 0.45 2.79e-18 Morning vs. evening chronotype; LIHC cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs17094222 0.812 rs7900417 chr10:102434576 T/C cg26540559 chr10:102447443 NA 0.33 6.23 0.32 1.36e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs703842 1.000 rs11172333 chr12:58170335 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.88 14.38 0.61 5.1e-37 Multiple sclerosis; LIHC cis rs8017423 0.904 rs11623741 chr14:90804474 C/T cg04374321 chr14:90722782 PSMC1 0.68 12.48 0.56 1.02e-29 Mortality in heart failure; LIHC cis rs9916302 0.904 rs7221875 chr17:37543328 G/A cg03013999 chr17:37608204 MED1 -0.36 -5.96 -0.31 6.11e-9 Glomerular filtration rate (creatinine); LIHC cis rs4919087 0.715 rs2484881 chr10:98998266 C/T cg25902810 chr10:99078978 FRAT1 -0.51 -5.91 -0.3 8.29e-9 Monocyte count; LIHC cis rs7223966 1.000 rs78172786 chr17:61847114 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 7.05 0.36 1e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9309473 0.579 rs1852644 chr2:73597718 A/G cg20560298 chr2:73613845 ALMS1 -0.45 -7.39 -0.37 1.14e-12 Metabolite levels; LIHC cis rs9457247 0.967 rs1794696 chr6:167396174 T/C cg23791538 chr6:167370224 RNASET2 -0.59 -9.39 -0.45 8.98e-19 Crohn's disease; LIHC cis rs2580764 0.598 rs6726158 chr2:55239202 G/T cg09592903 chr2:55203963 RTN4 -0.68 -12.29 -0.55 5.3e-29 Mean platelet volume; LIHC cis rs7116495 0.737 rs6592456 chr11:71737663 G/A cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.06e-17 Severe influenza A (H1N1) infection; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg00424677 chr19:32836465 ZNF507 -0.51 -6.24 -0.32 1.27e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs36051895 0.632 rs12337481 chr9:5134599 T/G cg02405213 chr9:5042618 JAK2 -0.67 -11.44 -0.53 6.78e-26 Pediatric autoimmune diseases; LIHC cis rs2540917 0.669 rs12105503 chr2:60650742 A/G cg00543073 chr2:60773386 BCL11A -0.33 -6.54 -0.33 2.28e-10 Mean corpuscular volume; LIHC cis rs2180341 1.000 rs9321073 chr6:127609691 C/T cg24812749 chr6:127587940 RNF146 1.07 16.12 0.66 7.17e-44 Breast cancer; LIHC cis rs67311347 1.000 rs9874006 chr3:40471596 G/A cg00656387 chr3:40428638 ENTPD3 0.42 7.02 0.35 1.21e-11 Renal cell carcinoma; LIHC cis rs9581857 0.547 rs9581881 chr13:28106637 A/G cg22138327 chr13:27999177 GTF3A 0.75 5.91 0.3 8.09e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs7131987 0.903 rs7970390 chr12:29398655 A/G cg16970926 chr12:29381810 FAR2 0.33 7.2 0.36 3.77e-12 QT interval; LIHC cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs10216189 1.000 rs4724699 chr7:5526712 G/A cg05318486 chr7:5553423 FBXL18 -0.57 -8.46 -0.42 8.15e-16 Relative hand skill in reading disability; LIHC cis rs7602441 0.521 rs12052706 chr2:14765777 A/G cg06545361 chr2:14773388 FAM84A 0.52 5.97 0.31 5.9e-9 Visceral adipose tissue adjusted for BMI; LIHC cis rs7618501 1.000 rs35261599 chr3:49773236 G/A cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs7582720 1.000 rs72932573 chr2:203861113 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.1 0.31 2.88e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs8017423 0.967 rs2282030 chr14:90730265 G/A cg14092571 chr14:90743983 NA -0.41 -6.53 -0.33 2.34e-10 Mortality in heart failure; LIHC cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg24879335 chr3:133465180 TF 0.28 6.45 0.33 3.83e-10 Iron status biomarkers; LIHC cis rs7107174 0.901 rs10899496 chr11:78123831 A/G cg02023728 chr11:77925099 USP35 0.38 6.84 0.35 3.69e-11 Testicular germ cell tumor; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10149326 chr7:6630190 C7orf26 -0.45 -6.5 -0.33 2.85e-10 Pancreatic cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01295842 chr19:16683254 SLC35E1 -0.49 -6.39 -0.33 5.36e-10 Systolic blood pressure; LIHC cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg11764359 chr7:65958608 NA 0.59 6.14 0.32 2.32e-9 Diabetic kidney disease; LIHC cis rs12478296 1.000 rs56162244 chr2:243018690 A/G cg06360820 chr2:242988706 NA -0.79 -11.58 -0.53 2.18e-26 Obesity-related traits; LIHC cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.28e-9 Menopause (age at onset); LIHC cis rs597539 0.652 rs559032 chr11:68710847 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.74 10.28 0.49 9.02e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg18252515 chr7:66147081 NA 1.3 16.95 0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg02290350 chr8:58132656 NA 0.49 10.03 0.48 6.34e-21 Developmental language disorder (linguistic errors); LIHC cis rs2303759 0.670 rs45549132 chr19:49794028 G/T cg22307029 chr19:49891270 CCDC155 0.58 8.91 0.43 3.08e-17 Multiple sclerosis; LIHC cis rs6762 0.748 rs1130719 chr11:838760 T/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.8 -9.83 -0.47 2.95e-20 Mean platelet volume; LIHC cis rs6430585 0.528 rs114760827 chr2:136661110 G/A cg07305463 chr2:136567211 LCT -0.39 -5.98 -0.31 5.48e-9 Corneal structure; LIHC cis rs738322 0.574 rs28653361 chr22:38570700 C/A cg25457927 chr22:38595422 NA -0.32 -7.25 -0.36 2.84e-12 Cutaneous nevi; LIHC cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg23758822 chr17:41437982 NA 0.91 16.91 0.67 4.8e-47 Menopause (age at onset); LIHC cis rs36051895 0.622 rs12335546 chr9:5072182 C/T cg02405213 chr9:5042618 JAK2 -0.71 -12.84 -0.57 4.67e-31 Pediatric autoimmune diseases; LIHC cis rs59698941 0.943 rs66732439 chr5:132234702 A/G cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg10802521 chr3:52805072 NEK4 -0.42 -6.98 -0.35 1.54e-11 Bipolar disorder; LIHC cis rs903552 0.800 rs6598478 chr15:102001696 A/T cg19295451 chr15:102010161 PCSK6 -0.45 -6.05 -0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs634534 0.561 rs14157 chr11:65769780 T/G cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.98 0.31 5.48e-9 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs2274273 0.837 rs59871474 chr14:55779363 T/C cg01864836 chr14:55583639 NA -0.37 -6.56 -0.33 1.95e-10 Protein biomarker; LIHC cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg19016816 chr7:1267987 NA 0.26 5.8 0.3 1.49e-8 Bipolar disorder and schizophrenia; LIHC cis rs5758511 0.679 rs55867855 chr22:42623258 G/A cg20195005 chr22:42527684 CYP2D6 0.31 5.96 0.31 6.14e-9 Birth weight; LIHC cis rs929354 0.742 rs7784442 chr7:156934475 G/C cg17757837 chr7:157058334 UBE3C 0.72 11.6 0.53 1.79e-26 Body mass index; LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg00121389 chr8:17555302 MTUS1 0.53 6.95 0.35 1.87e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs35306767 0.903 rs12769002 chr10:927666 C/G cg26597838 chr10:835615 NA -1.49 -16.54 -0.67 1.41e-45 Eosinophil percentage of granulocytes; LIHC cis rs7192750 0.583 rs2550043 chr16:72067491 T/C cg14768367 chr16:72042858 DHODH 0.63 6.18 0.32 1.77e-9 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs651907 0.557 rs34947019 chr3:101532235 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.63 10.05 0.48 5.37e-21 Colorectal cancer; LIHC cis rs651907 0.557 rs7651721 chr3:101393583 C/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.36 0.56 2.93e-29 Colorectal cancer; LIHC cis rs2228479 0.850 rs12596934 chr16:89841605 T/G cg00800038 chr16:89945340 TCF25 -0.63 -9.48 -0.46 4.32e-19 Skin colour saturation; LIHC cis rs963731 0.649 rs1454223 chr2:39224351 G/T cg04010122 chr2:39346883 SOS1 -0.7 -5.97 -0.31 5.98e-9 Corticobasal degeneration; LIHC cis rs9788682 1.000 rs2036534 chr15:78826948 T/C cg06917634 chr15:78832804 PSMA4 -0.54 -7.68 -0.38 1.64e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7918232 0.830 rs7915902 chr10:27410734 T/C cg14240646 chr10:27532245 ACBD5 -0.66 -6.3 -0.32 9.05e-10 Breast cancer; LIHC cis rs1348850 0.554 rs1374438 chr2:178376684 A/G cg27490568 chr2:178487706 NA 1.0 11.25 0.52 3.51e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9640161 0.659 rs59572505 chr7:150014986 C/T cg21361702 chr7:150065534 REPIN1 0.47 6.54 0.33 2.25e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs9914988 0.887 rs12451790 chr17:27112000 C/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23526204 chr20:43992176 SYS1;SYS1-DBNDD2 0.46 6.89 0.35 2.77e-11 Lung function (FEV1/FVC); LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg05064044 chr6:292385 DUSP22 -0.51 -6.72 -0.34 7.68e-11 Menopause (age at onset); LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg00280220 chr17:61926910 NA 0.41 6.74 0.34 6.76e-11 Prudent dietary pattern; LIHC cis rs10751667 0.666 rs10902247 chr11:953686 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.09 0.48 4.1e-21 Alzheimer's disease (late onset); LIHC trans rs61931739 0.500 rs6488218 chr12:34452587 T/C cg26384229 chr12:38710491 ALG10B 0.65 8.37 0.41 1.55e-15 Morning vs. evening chronotype; LIHC cis rs8081395 0.627 rs180536 chr17:57996806 G/A cg02344993 chr17:57696989 CLTC 0.45 7.55 0.38 3.92e-13 White blood cell count; LIHC cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg15691649 chr6:25882328 NA -0.51 -7.33 -0.37 1.65e-12 Blood metabolite levels; LIHC cis rs17253792 0.822 rs112739186 chr14:56065167 A/T cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs317689 0.690 rs570256 chr12:69662929 A/T cg22834771 chr12:69754056 YEATS4 -0.4 -6.01 -0.31 4.75e-9 Response to diuretic therapy; LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg22029157 chr1:209979665 IRF6 0.5 8.9 0.43 3.35e-17 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.75 0.39 1.03e-13 Obesity-related traits; LIHC cis rs7772486 0.754 rs13214277 chr6:146136125 G/T cg23711669 chr6:146136114 FBXO30 0.75 13.69 0.6 2.53e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs1577917 0.958 rs11756510 chr6:86699794 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.63 -0.46 1.45e-19 Response to antipsychotic treatment; LIHC cis rs6582630 0.638 rs11182428 chr12:38526387 T/C cg26384229 chr12:38710491 ALG10B -0.49 -6.85 -0.35 3.49e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs12791968 0.917 rs11038239 chr11:45002012 A/G cg11846598 chr11:44996168 LOC221122 -0.44 -7.88 -0.39 4.51e-14 Inhibitory control; LIHC trans rs11098499 0.865 rs3956464 chr4:120256764 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.26 0.41 3.23e-15 Corneal astigmatism; LIHC cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg00166722 chr3:10149974 C3orf24 0.51 5.92 0.3 7.85e-9 Alzheimer's disease; LIHC cis rs1555322 0.505 rs639763 chr20:33861904 C/T cg07134254 chr20:33865797 NA 0.51 5.83 0.3 1.25e-8 Attention deficit hyperactivity disorder; LIHC cis rs11098499 0.954 rs59866101 chr4:120296591 T/G cg09307838 chr4:120376055 NA 0.76 11.64 0.53 1.32e-26 Corneal astigmatism; LIHC cis rs367615 0.661 rs9326773 chr5:108833523 C/T cg17395555 chr5:108820864 NA 0.39 8.63 0.42 2.35e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs11628318 0.617 rs11626481 chr14:103086356 A/G cg12046867 chr14:103022105 NA -0.49 -6.59 -0.34 1.65e-10 Platelet count; LIHC cis rs12893668 0.703 rs8017993 chr14:104047734 A/G cg24130564 chr14:104152367 KLC1 -0.54 -8.94 -0.44 2.54e-17 Reticulocyte count; LIHC cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg16434002 chr17:42200994 HDAC5 0.42 6.29 0.32 9.8e-10 Total body bone mineral density; LIHC cis rs2243480 1.000 rs2243480 chr7:65599196 C/T cg25894440 chr7:65020034 NA -0.53 -5.87 -0.3 1.03e-8 Diabetic kidney disease; LIHC cis rs6835098 1.000 rs6826412 chr4:174109622 C/T cg27433088 chr4:174089019 GALNT7 0.41 6.95 0.35 1.86e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs1865760 0.929 rs9358896 chr6:25943197 C/A cg03264133 chr6:25882463 NA -0.41 -6.24 -0.32 1.33e-9 Height; LIHC cis rs2070488 1.000 rs34258593 chr3:38464565 T/C cg24069376 chr3:38537580 EXOG 0.44 7.99 0.4 2.12e-14 Electrocardiographic conduction measures; LIHC cis rs2228479 0.850 rs62052714 chr16:89857180 T/C cg04013166 chr16:89971882 TCF25 0.49 5.84 0.3 1.22e-8 Skin colour saturation; LIHC cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg18306943 chr3:40428807 ENTPD3 0.36 6.33 0.32 7.52e-10 Renal cell carcinoma; LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg05185784 chr16:90016020 DEF8 -0.44 -6.0 -0.31 4.97e-9 Skin colour saturation; LIHC cis rs7945705 0.818 rs1988708 chr11:8882893 C/A cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -9.45 -0.45 5.64e-19 Hemoglobin concentration; LIHC cis rs11630290 0.592 rs12594446 chr15:64156674 G/T cg12036633 chr15:63758958 NA 0.64 6.86 0.35 3.28e-11 Iris characteristics; LIHC cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg02475777 chr4:1388615 CRIPAK 0.43 6.43 0.33 4.3e-10 Longevity; LIHC cis rs1799949 0.965 rs799912 chr17:41257134 T/C cg25072359 chr17:41440525 NA 0.42 6.69 0.34 9.31e-11 Menopause (age at onset); LIHC cis rs744487 0.960 rs11581688 chr1:234726532 C/G cg09691134 chr1:234734475 NA 0.36 5.75 0.3 1.98e-8 LDL cholesterol; LIHC cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg16405210 chr4:1374714 KIAA1530 0.41 6.07 0.31 3.46e-9 Obesity-related traits; LIHC cis rs1401999 1.000 rs2313217 chr3:183635997 A/G cg05044414 chr3:183734942 ABCC5 0.34 5.91 0.3 8.16e-9 Anterior chamber depth; LIHC cis rs769267 0.929 rs2905421 chr19:19457908 G/T cg21559469 chr19:19431446 KIAA0892;SF4 0.47 6.6 0.34 1.57e-10 Tonsillectomy; LIHC cis rs921968 0.643 rs864990 chr2:219494037 G/A cg02985541 chr2:219472218 PLCD4 0.44 8.13 0.4 7.89e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs35110281 0.712 rs1454648 chr21:45053815 C/T cg04455712 chr21:45112962 RRP1B 0.47 7.94 0.39 2.91e-14 Mean corpuscular volume; LIHC cis rs11718455 0.563 rs6809096 chr3:43902494 G/C cg08738300 chr3:44038990 NA 0.36 6.08 0.31 3.16e-9 Coronary artery disease; LIHC cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg20607798 chr8:58055168 NA 0.73 8.06 0.4 1.25e-14 Developmental language disorder (linguistic errors); LIHC cis rs10789491 1.000 rs4660956 chr1:47158486 A/G cg15501359 chr1:47185051 KIAA0494 0.8 10.78 0.5 1.55e-23 Response to hepatitis C treatment; LIHC cis rs7503168 1.000 rs1037590 chr17:33902635 G/T cg20932281 chr17:33905541 PEX12 0.57 7.32 0.37 1.83e-12 Plateletcrit; LIHC cis rs11690935 0.595 rs788170 chr2:172919958 T/C cg13550731 chr2:172543902 DYNC1I2 0.56 9.62 0.46 1.54e-19 Schizophrenia; LIHC cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg13395646 chr4:1353034 KIAA1530 -0.43 -6.03 -0.31 4.29e-9 Longevity; LIHC cis rs992157 0.560 rs1514132 chr2:219084082 C/T cg00012203 chr2:219082015 ARPC2 -0.87 -15.11 -0.63 6.87e-40 Colorectal cancer; LIHC cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg16145915 chr7:1198662 ZFAND2A -0.34 -8.21 -0.41 4.47e-15 Longevity;Endometriosis; LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg11905131 chr22:24372483 LOC391322 -0.69 -10.11 -0.48 3.37e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11122272 0.735 rs2295420 chr1:231485640 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.33 0.45 1.39e-18 Hemoglobin concentration; LIHC cis rs7582720 1.000 rs72936332 chr2:204056678 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg07636037 chr3:49044803 WDR6 0.75 12.46 0.56 1.27e-29 Menarche (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06329143 chr18:48556512 SMAD4 -0.44 -6.26 -0.32 1.15e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4700695 0.841 rs448454 chr5:65293462 G/A cg21114390 chr5:65439923 SFRS12 0.49 6.58 0.34 1.77e-10 Facial morphology (factor 19); LIHC cis rs3853824 0.965 rs6503766 chr17:54899945 G/A cg13675837 chr17:54910204 DGKE 0.42 5.93 0.31 7.59e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs67981189 0.574 rs221916 chr14:71592078 C/T cg15816911 chr14:71606274 NA -0.44 -7.03 -0.36 1.12e-11 Schizophrenia; LIHC cis rs919433 0.713 rs55642934 chr2:198491110 C/T cg10820045 chr2:198174542 NA 0.51 7.87 0.39 4.87e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11098499 0.530 rs114866537 chr4:120258608 A/T cg09307838 chr4:120376055 NA 0.62 9.8 0.47 3.93e-20 Corneal astigmatism; LIHC cis rs13392177 0.660 rs12988046 chr2:219073804 A/G cg00012203 chr2:219082015 ARPC2 -0.76 -11.32 -0.52 1.94e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs4253772 0.591 rs8143066 chr22:46656607 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.67 6.09 0.31 2.99e-9 LDL cholesterol;Cholesterol, total; LIHC cis rs4665809 1.000 rs4665298 chr2:26256378 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.68 -8.29 -0.41 2.67e-15 Gut microbiome composition (summer); LIHC cis rs600806 0.778 rs2140923 chr1:110004990 C/T cg02415029 chr1:110025642 ATXN7L2 -0.52 -6.68 -0.34 9.48e-11 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.816 rs113624314 chr9:111689953 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 9.1 0.44 7.64e-18 Menarche (age at onset); LIHC cis rs61990749 0.571 rs2364841 chr14:78284036 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.48 -6.01 -0.31 4.79e-9 Fibroblast growth factor basic levels; LIHC cis rs13191362 1.000 rs13215491 chr6:163010325 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.01 0.31 4.83e-9 Menopause (age at onset); LIHC cis rs7584330 0.910 rs72620830 chr2:238396985 C/T cg14458575 chr2:238380390 NA 0.38 5.76 0.3 1.83e-8 Prostate cancer; LIHC cis rs655641 1.000 rs2458500 chr11:85779310 A/G cg09030501 chr11:85779252 PICALM -0.51 -6.01 -0.31 4.83e-9 Platelet count; LIHC cis rs10791097 0.629 rs11222361 chr11:130731424 T/G cg09137382 chr11:130731461 NA 0.44 6.83 0.35 3.88e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10870270 0.913 rs4550 chr10:133781798 C/T cg26149184 chr10:133730230 NA 0.47 7.44 0.37 7.99e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6089584 0.927 rs2296083 chr20:60574216 C/T cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs8017423 0.967 rs11844225 chr14:90726676 G/A cg14092571 chr14:90743983 NA -0.39 -6.15 -0.32 2.13e-9 Mortality in heart failure; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.64 0.38 2.16e-13 Height; LIHC cis rs311392 1.000 rs2666871 chr8:55089184 C/T cg20636351 chr8:55087400 NA -0.39 -8.16 -0.4 6.68e-15 Pelvic organ prolapse (moderate/severe); LIHC cis rs3736485 0.903 rs11630842 chr15:51750652 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.35 -0.32 6.98e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1059312 0.932 rs4760592 chr12:129287149 G/C cg09035930 chr12:129282057 SLC15A4 0.68 12.99 0.57 1.26e-31 Systemic lupus erythematosus; LIHC cis rs4631830 0.832 rs11005089 chr10:51510813 C/A cg20129853 chr10:51489980 NA 0.42 8.98 0.44 1.84e-17 Prostate-specific antigen levels; LIHC cis rs1577917 0.739 rs6922 chr6:86205323 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 8.0 0.4 1.96e-14 Response to antipsychotic treatment; LIHC cis rs6726292 0.539 rs34928331 chr2:55227383 G/T cg09592903 chr2:55203963 RTN4 -0.47 -7.2 -0.36 3.92e-12 Obesity (extreme); LIHC cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg12386194 chr3:101231763 SENP7 0.52 7.58 0.38 3.23e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs875971 0.660 rs12698534 chr7:65986845 C/T cg11764359 chr7:65958608 NA 0.72 11.04 0.51 1.9e-24 Aortic root size; LIHC cis rs3780378 0.682 rs7861755 chr9:5273180 C/T cg02405213 chr9:5042618 JAK2 -0.47 -8.12 -0.4 8.45e-15 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs9911578 0.967 rs12603238 chr17:57130785 C/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.54 -0.69 1.42e-49 Intelligence (multi-trait analysis); LIHC cis rs8038465 0.638 rs12591473 chr15:73967485 A/T cg15420318 chr15:73925796 NPTN 0.39 6.01 0.31 4.72e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17685 0.712 rs60721456 chr7:75743820 T/A cg01364799 chr7:75623366 TMEM120A -0.4 -6.02 -0.31 4.6e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11190604 1.000 rs11190607 chr10:102303614 C/T cg07080220 chr10:102295463 HIF1AN 0.52 7.26 0.37 2.62e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2404602 0.692 rs8024476 chr15:76983954 T/C cg03037974 chr15:76606532 NA 0.73 14.53 0.62 1.41e-37 Blood metabolite levels; LIHC cis rs6120849 0.586 rs2025096 chr20:33540000 G/A cg24642439 chr20:33292090 TP53INP2 0.67 7.78 0.39 8.77e-14 Protein C levels; LIHC cis rs738322 0.967 rs4380 chr22:38569529 T/C cg17652424 chr22:38574118 PLA2G6 -0.19 -5.75 -0.3 1.96e-8 Cutaneous nevi; LIHC cis rs116095464 0.558 rs6882584 chr5:223411 A/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs57590327 0.503 rs2372905 chr3:81504592 C/G cg07356753 chr3:81810745 GBE1 0.46 6.91 0.35 2.38e-11 Extraversion; LIHC cis rs11628318 0.538 rs1190339 chr14:103103876 C/T cg01864069 chr14:103024347 NA -0.34 -5.78 -0.3 1.71e-8 Platelet count; LIHC trans rs1814175 0.645 rs1963215 chr11:49931486 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Bipolar disorder; LIHC cis rs11191419 1 rs11191419 chr10:104612335 T/A cg11784071 chr10:104629166 AS3MT -0.35 -5.79 -0.3 1.64e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2625529 0.713 rs12903980 chr15:72165549 C/T cg16672083 chr15:72433130 SENP8 -0.32 -5.9 -0.3 8.92e-9 Red blood cell count; LIHC cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg13397359 chr6:42928475 GNMT 0.71 10.37 0.49 4.26e-22 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs1961637 0.603 rs1550423 chr2:223885812 C/T cg04229842 chr17:55038233 COIL -0.38 -6.12 -0.31 2.52e-9 Oropharynx cancer; LIHC cis rs11122272 0.735 rs2474623 chr1:231513993 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs933688 0.502 rs4916858 chr5:90601290 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.46 -7.58 -0.38 3.2e-13 Smoking behavior; LIHC cis rs9902453 0.817 rs59420007 chr17:28196114 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.31 0.55 4.46e-29 Coffee consumption (cups per day); LIHC cis rs12478296 1.000 rs55758933 chr2:243040289 T/C cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.1e-27 Obesity-related traits; LIHC cis rs7534824 0.625 rs61780331 chr1:101480610 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 6.76 0.34 5.97e-11 Refractive astigmatism; LIHC cis rs72653721 0.730 rs17764682 chr6:11058815 A/C cg13562911 chr6:11044106 ELOVL2 0.52 7.56 0.38 3.74e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs12022452 0.544 rs11208423 chr1:41029614 T/C cg25568243 chr1:40974465 DEM1 0.44 5.81 0.3 1.46e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs67311347 0.911 rs6775936 chr3:40377399 T/G cg16822855 chr3:40428330 ENTPD3 0.33 6.06 0.31 3.59e-9 Renal cell carcinoma; LIHC cis rs11229555 0.598 rs7930623 chr11:58197641 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9394841 0.692 rs9394837 chr6:41848088 G/A cg08135965 chr6:41755394 TOMM6 0.44 5.91 0.3 8.34e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs4665809 1.000 rs4665811 chr2:26260017 A/G cg27170947 chr2:26402098 FAM59B -0.68 -8.38 -0.41 1.39e-15 Gut microbiome composition (summer); LIHC cis rs782590 0.721 rs1084525 chr2:55929430 C/T cg03859395 chr2:55845619 SMEK2 0.86 14.22 0.61 2.18e-36 Metabolic syndrome; LIHC cis rs7769051 1.000 rs7761365 chr6:133101561 T/A cg07930552 chr6:133119739 C6orf192 0.71 6.85 0.35 3.46e-11 Type 2 diabetes nephropathy; LIHC cis rs8017423 1.000 rs4904644 chr14:90665689 A/G cg14092571 chr14:90743983 NA 0.39 6.07 0.31 3.38e-9 Mortality in heart failure; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg27493151 chr19:38701994 DPF1 0.44 6.36 0.33 6.52e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6831352 0.918 rs29001203 chr4:100053091 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.41 -0.49 3.05e-22 Alcohol dependence; LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg00280220 chr17:61926910 NA 0.43 6.83 0.35 3.79e-11 Prudent dietary pattern; LIHC cis rs7258465 0.965 rs10408290 chr19:18542701 C/T cg10790698 chr19:18539756 SSBP4 -0.37 -7.45 -0.37 7.91e-13 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09747232 chr8:103827049 NA 0.45 6.33 0.32 7.65e-10 Pancreatic cancer; LIHC cis rs1881396 0.891 rs2141372 chr2:27827196 G/T cg27432699 chr2:27873401 GPN1 0.45 6.72 0.34 7.71e-11 Nonalcoholic fatty liver disease; LIHC cis rs9910055 0.530 rs2269907 chr17:42294215 G/A cg09913183 chr17:42254507 C17orf65;ASB16 0.64 9.4 0.45 7.82e-19 Total body bone mineral density; LIHC trans rs11098499 0.866 rs12510451 chr4:120289143 C/T cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs2932538 0.922 rs4838961 chr1:113163967 T/C cg22162597 chr1:113214053 CAPZA1 -0.73 -11.24 -0.52 3.81e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs2075165 0.901 rs10908492 chr1:156224795 C/T cg20302342 chr1:156215951 PAQR6 0.35 6.59 0.34 1.63e-10 Tonsillectomy; LIHC trans rs801193 1.000 rs2659909 chr7:66160279 G/A cg26939375 chr7:64535504 NA 0.41 6.46 0.33 3.51e-10 Aortic root size; LIHC cis rs36051895 0.589 rs4560849 chr9:5203866 C/G cg02405213 chr9:5042618 JAK2 -0.64 -10.69 -0.5 3.32e-23 Pediatric autoimmune diseases; LIHC cis rs9918079 0.542 rs6414765 chr4:15626493 G/A cg21329975 chr4:15471214 CC2D2A -0.38 -5.75 -0.3 2.03e-8 Obesity-related traits; LIHC cis rs5753037 0.615 rs131279 chr22:30155251 G/C cg01021169 chr22:30184971 ASCC2 -0.31 -5.76 -0.3 1.89e-8 Type 1 diabetes; LIHC cis rs4975709 0.569 rs1684965 chr5:1865248 A/G cg15595755 chr5:1867978 NA 0.41 8.26 0.41 3.16e-15 Cardiovascular disease risk factors; LIHC cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg05665937 chr4:1216051 CTBP1 0.45 5.99 0.31 5.29e-9 Obesity-related traits; LIHC cis rs2257205 0.600 rs8071081 chr17:56709055 T/G cg12560992 chr17:57184187 TRIM37 0.68 7.43 0.37 8.67e-13 Pancreatic cancer; LIHC cis rs4906332 0.868 rs4900578 chr14:103926010 A/T cg19000871 chr14:103996768 TRMT61A -0.47 -7.94 -0.39 2.98e-14 Coronary artery disease; LIHC cis rs7572733 0.555 rs2164071 chr2:198915467 T/C cg00792783 chr2:198669748 PLCL1 0.41 5.97 0.31 5.97e-9 Dermatomyositis; LIHC cis rs668210 0.894 rs1786171 chr11:65769809 G/C cg02202077 chr11:65769826 EIF1AD;BANF1 0.55 6.79 0.34 4.98e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg19723775 chr5:179050963 HNRNPH1 0.41 6.39 0.33 5.57e-10 Lung cancer; LIHC cis rs2286503 0.752 rs2286504 chr7:22854847 G/T cg11367502 chr7:22862612 TOMM7 0.47 8.14 0.4 7.59e-15 Fibrinogen; LIHC cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg15105969 chr2:36825350 FEZ2 0.58 7.36 0.37 1.39e-12 Height; LIHC cis rs1707322 0.717 rs1547925 chr1:46085356 C/T cg03146154 chr1:46216737 IPP -0.55 -9.24 -0.45 2.66e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9790314 1.000 rs9790314 chr3:161019558 T/C cg04691961 chr3:161091175 C3orf57 -0.33 -5.75 -0.3 1.93e-8 Morning vs. evening chronotype; LIHC cis rs4718428 0.705 rs3800817 chr7:66263550 T/A cg12165864 chr7:66369176 NA -0.47 -6.88 -0.35 2.94e-11 Corneal structure; LIHC cis rs2153535 0.505 rs9405395 chr6:8468622 T/A cg23788917 chr6:8435910 SLC35B3 0.61 8.68 0.42 1.64e-16 Motion sickness; LIHC cis rs12644436 0.711 rs4693188 chr4:88787174 A/G cg06891869 chr4:88767617 MEPE 0.42 7.6 0.38 2.93e-13 HIV-1 viral setpoint; LIHC cis rs72772090 0.908 rs76539796 chr5:96038675 G/A cg17330273 chr5:96107758 CAST;ERAP1 -0.57 -6.47 -0.33 3.46e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9549367 1.000 rs9549367 chr13:113911532 C/G cg18105134 chr13:113819100 PROZ -0.57 -9.78 -0.47 4.48e-20 Platelet distribution width; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg12419862 chr22:24373484 LOC391322 -0.77 -11.92 -0.54 1.27e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs7618501 0.521 rs11130222 chr3:49901060 A/T cg21659725 chr3:3221576 CRBN 0.57 8.23 0.41 3.85e-15 Intelligence (multi-trait analysis); LIHC cis rs4660306 0.744 rs11211114 chr1:45926243 G/C cg03123370 chr1:45965343 CCDC163P;MMACHC 0.63 6.84 0.35 3.71e-11 Homocysteine levels; LIHC cis rs8141529 0.719 rs2097461 chr22:29191879 T/C cg15103426 chr22:29168792 CCDC117 0.63 10.87 0.51 7.53e-24 Lymphocyte counts; LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg18306943 chr3:40428807 ENTPD3 0.42 7.38 0.37 1.21e-12 Renal cell carcinoma; LIHC cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg18402987 chr7:1209562 NA 0.87 6.27 0.32 1.08e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1023500 0.596 rs5758562 chr22:42448238 C/G cg04733989 chr22:42467013 NAGA 0.66 9.36 0.45 1.09e-18 Schizophrenia; LIHC cis rs7638909 0.512 rs6804918 chr3:38598956 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.41 -6.04 -0.31 3.96e-9 Electrocardiographic conduction measures; LIHC cis rs4665809 1.000 rs11126364 chr2:26314515 A/G cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.02e-15 Gut microbiome composition (summer); LIHC cis rs12908161 0.959 rs34342559 chr15:85331271 A/G cg17507749 chr15:85114479 UBE2QP1 0.61 6.85 0.35 3.51e-11 Schizophrenia; LIHC cis rs4718428 0.672 rs13241598 chr7:66300652 A/G cg18252515 chr7:66147081 NA -0.68 -9.31 -0.45 1.61e-18 Corneal structure; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg11494091 chr17:61959527 GH2 0.46 8.26 0.41 3.27e-15 Prudent dietary pattern; LIHC cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg00825309 chr19:58991885 ZNF446 -0.53 -8.36 -0.41 1.64e-15 Uric acid clearance; LIHC cis rs858239 0.539 rs6955726 chr7:23186691 A/G cg23682824 chr7:23144976 KLHL7 0.43 6.47 0.33 3.41e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg22442454 chr1:209979470 IRF6 0.4 6.11 0.31 2.77e-9 Cleft lip with or without cleft palate; LIHC cis rs9916302 0.904 rs2303316 chr17:37704217 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.21 -0.58 1.78e-32 Glomerular filtration rate (creatinine); LIHC trans rs61931739 0.534 rs11053047 chr12:34161084 C/T cg26384229 chr12:38710491 ALG10B 0.59 7.57 0.38 3.41e-13 Morning vs. evening chronotype; LIHC cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg25427524 chr10:38739819 LOC399744 -0.72 -13.89 -0.6 4.19e-35 Extrinsic epigenetic age acceleration; LIHC cis rs1008375 0.932 rs9291660 chr4:17663414 A/G cg16339924 chr4:17578868 LAP3 0.52 6.8 0.35 4.56e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1707322 1.000 rs10158032 chr1:46332701 T/C cg03146154 chr1:46216737 IPP 0.47 7.61 0.38 2.62e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7613875 0.620 rs3774734 chr3:50108792 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.6 -0.34 1.62e-10 Body mass index; LIHC cis rs1005277 0.579 rs1614236 chr10:38502996 C/T cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.78 -0.3 1.71e-8 Extrinsic epigenetic age acceleration; LIHC cis rs796364 0.906 rs281789 chr2:200780698 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.01 0.44 1.49e-17 Schizophrenia; LIHC cis rs6060717 0.610 rs1891151 chr20:34612726 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.44 -7.47 -0.37 6.82e-13 Hip circumference adjusted for BMI; LIHC cis rs66887589 0.616 rs13113885 chr4:120221176 G/C cg09307838 chr4:120376055 NA 0.54 7.87 0.39 4.77e-14 Diastolic blood pressure; LIHC cis rs2290416 0.892 rs34178175 chr8:144664687 G/A cg26536354 chr8:144654954 C8orf73 0.53 5.77 0.3 1.75e-8 Attention deficit hyperactivity disorder; LIHC cis rs5769707 0.967 rs2071904 chr22:50034477 C/T cg01652190 chr22:50026171 C22orf34 -0.31 -7.09 -0.36 7.83e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7520050 0.966 rs10749860 chr1:46328210 C/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.05 0.31 3.87e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6752107 0.901 rs11679791 chr2:234156536 G/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.49 7.09 0.36 7.59e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs477692 0.569 rs10764885 chr10:131310207 G/A cg05714579 chr10:131428358 MGMT 0.41 6.56 0.33 2e-10 Response to temozolomide; LIHC cis rs4407350 0.748 rs131170 chr22:44901601 C/A cg04154583 chr22:44889756 LDOC1L 0.29 5.75 0.3 1.99e-8 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.754 rs2268994 chr6:88185386 A/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.11 -0.36 7.03e-12 Monocyte percentage of white cells; LIHC cis rs644799 0.625 rs1255175 chr11:95471186 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.62 10.19 0.48 1.85e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4780401 0.609 rs4781143 chr16:11809721 T/G cg01061890 chr16:11836724 TXNDC11 -0.65 -10.36 -0.49 4.78e-22 Rheumatoid arthritis; LIHC trans rs6489882 0.867 rs7298184 chr12:113368249 C/A cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05127153 chr1:6452942 ACOT7 0.44 6.12 0.31 2.5e-9 Lung function (FEV1/FVC); LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.18 -0.4 5.48e-15 Lymphocyte counts; LIHC cis rs317689 0.819 rs317667 chr12:69703754 G/T cg20891283 chr12:69753455 YEATS4 0.58 8.78 0.43 7.69e-17 Response to diuretic therapy; LIHC cis rs6062509 0.839 rs6062298 chr20:62301970 G/A cg03999872 chr20:62272968 STMN3 0.38 5.73 0.3 2.2e-8 Prostate cancer; LIHC cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg06238570 chr21:40685208 BRWD1 0.61 7.31 0.37 1.85e-12 Cognitive function; LIHC trans rs8002861 0.810 rs2275252 chr13:44454374 A/C cg17145862 chr1:211918768 LPGAT1 0.68 13.17 0.58 2.6e-32 Leprosy; LIHC cis rs3806843 0.676 rs778594 chr5:140027304 T/C cg16577123 chr5:140027231 NDUFA2;IK -0.42 -6.06 -0.31 3.63e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs600806 0.778 rs2115787 chr1:110003840 T/G cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.21 -0.32 1.54e-9 Intelligence (multi-trait analysis); LIHC cis rs732505 1.000 rs10417622 chr19:5592547 T/C cg26242866 chr19:5711310 LONP1 0.89 6.52 0.33 2.59e-10 vWF and FVIII levels; LIHC cis rs1580019 0.587 rs7806113 chr7:32553084 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.15 26.69 0.82 1.33e-85 Cognitive ability; LIHC cis rs4268898 0.552 rs11125444 chr2:24367205 G/T cg06627628 chr2:24431161 ITSN2 0.46 6.7 0.34 8.64e-11 Asthma; LIHC cis rs9309473 1.000 rs11899740 chr2:73631212 G/A cg20560298 chr2:73613845 ALMS1 -0.58 -6.48 -0.33 3.13e-10 Metabolite levels; LIHC cis rs12188164 0.561 rs2721010 chr5:456915 A/G cg16584290 chr5:462447 EXOC3 0.37 6.03 0.31 4.16e-9 Cystic fibrosis severity; LIHC cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4407350 0.756 rs131158 chr22:44891873 A/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.39 -0.33 5.42e-10 Intelligence (multi-trait analysis); LIHC cis rs8067545 0.750 rs4925081 chr17:19991993 A/G cg13482628 chr17:19912719 NA -0.49 -8.23 -0.41 3.91e-15 Schizophrenia; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 23.03 0.78 1.56e-71 Prudent dietary pattern; LIHC cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg02187348 chr16:89574699 SPG7 0.52 7.72 0.39 1.31e-13 Multiple myeloma (IgH translocation); LIHC cis rs3815700 1.000 rs8109768 chr19:33095463 A/G cg02997394 chr19:33096574 ANKRD27 0.73 9.38 0.45 9.36e-19 Eosinophilic esophagitis; LIHC cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg22663859 chr13:21900854 NA 0.46 7.32 0.37 1.79e-12 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs17253792 0.822 rs79747476 chr14:56160485 C/A cg01858014 chr14:56050164 KTN1 -0.72 -7.4 -0.37 1.04e-12 Putamen volume; LIHC cis rs67311347 0.956 rs12633446 chr3:40505661 G/A cg13409248 chr3:40428643 ENTPD3 -0.44 -7.45 -0.37 7.75e-13 Renal cell carcinoma; LIHC cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.22 -0.45 3.08e-18 Electroencephalogram traits; LIHC cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg20295408 chr7:1910781 MAD1L1 -0.48 -7.07 -0.36 8.96e-12 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC trans rs1945213 0.694 rs11227181 chr11:55856053 C/T cg15704280 chr7:45808275 SEPT13 0.59 7.68 0.38 1.71e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs2439831 0.867 rs2447208 chr15:43933895 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.76 0.34 6.13e-11 Lung cancer in ever smokers; LIHC cis rs8062405 1.000 rs62036622 chr16:28837203 T/G cg16576597 chr16:28551801 NUPR1 0.36 5.75 0.3 2.01e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs116095464 0.558 rs10065584 chr5:253997 G/A cg22496380 chr5:211416 CCDC127 -1.15 -10.76 -0.5 1.93e-23 Breast cancer; LIHC cis rs921968 0.612 rs4674323 chr2:219517088 T/C cg18887096 chr2:219472410 PLCD4 0.39 6.76 0.34 6.11e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs6424115 1.000 rs7514394 chr1:24100223 A/G cg10978503 chr1:24200527 CNR2 -0.33 -8.01 -0.4 1.87e-14 Immature fraction of reticulocytes; LIHC cis rs807669 0.548 rs885979 chr22:19198375 T/C cg02655711 chr22:19163373 SLC25A1 0.34 5.87 0.3 1.04e-8 Metabolite levels; LIHC cis rs7119038 0.818 rs7942535 chr11:118681464 C/T cg19308663 chr11:118741387 NA -0.4 -6.18 -0.32 1.85e-9 Sjögren's syndrome; LIHC trans rs4332037 0.950 rs11771828 chr7:1941003 T/C cg11693508 chr17:37793320 STARD3 0.73 7.55 0.38 4.04e-13 Bipolar disorder; LIHC cis rs1816752 0.719 rs11843470 chr13:24997699 A/C cg02811702 chr13:24901961 NA 0.24 5.86 0.3 1.06e-8 Obesity-related traits; LIHC cis rs11696739 0.866 rs1535882 chr20:1600524 T/C cg15722679 chr20:1638393 SIRPG 0.41 7.91 0.39 3.5e-14 Mean platelet volume; LIHC cis rs9611565 0.559 rs1006407 chr22:41972032 T/C cg06481639 chr22:41940642 POLR3H -0.75 -6.83 -0.35 3.79e-11 Vitiligo; LIHC cis rs79149102 0.579 rs8039433 chr15:75367367 T/C cg17294928 chr15:75287854 SCAMP5 -0.45 -5.73 -0.3 2.23e-8 Lung cancer; LIHC cis rs477692 1.000 rs480643 chr10:131400308 A/G cg19680672 chr10:131412579 MGMT -0.45 -7.03 -0.36 1.14e-11 Response to temozolomide; LIHC cis rs3020736 0.500 rs8143153 chr22:42515637 G/C cg15557168 chr22:42548783 NA 0.44 6.96 0.35 1.73e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs6951245 0.935 rs79067319 chr7:1065548 C/T cg08132940 chr7:1081526 C7orf50 -0.76 -6.49 -0.33 3.02e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6964587 1.000 rs6944591 chr7:91642714 T/C cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg08219700 chr8:58056026 NA 0.46 5.8 0.3 1.48e-8 Developmental language disorder (linguistic errors); LIHC cis rs986417 0.901 rs1989477 chr14:61024867 T/C cg27398547 chr14:60952738 C14orf39 0.69 7.39 0.37 1.16e-12 Gut microbiota (bacterial taxa); LIHC cis rs1371867 0.846 rs1660351 chr8:101275034 C/T cg06002616 chr8:101225028 SPAG1 -0.34 -5.76 -0.3 1.9e-8 Atrioventricular conduction; LIHC cis rs7119038 0.818 rs11826521 chr11:118610549 G/T cg19308663 chr11:118741387 NA 0.43 5.74 0.3 2.14e-8 Sjögren's syndrome; LIHC cis rs10065203 0.527 rs181927 chr5:14351946 G/T cg26595256 chr5:14380529 TRIO -0.42 -6.55 -0.33 2.08e-10 Paclitaxel-induced neuropathy; LIHC cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg02951883 chr7:2050386 MAD1L1 -0.76 -12.99 -0.57 1.24e-31 Bipolar disorder and schizophrenia; LIHC cis rs12893668 0.644 rs12890820 chr14:104034849 T/C cg24130564 chr14:104152367 KLC1 -0.55 -9.15 -0.44 5.13e-18 Reticulocyte count; LIHC cis rs6570726 0.935 rs432086 chr6:145841593 C/T cg23711669 chr6:146136114 FBXO30 -0.56 -10.02 -0.48 7.03e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs722599 0.651 rs12887044 chr14:75255659 C/T cg08847533 chr14:75593920 NEK9 0.53 7.98 0.4 2.3e-14 IgG glycosylation; LIHC cis rs2991971 1.000 rs2991971 chr1:46012748 C/G cg15605315 chr1:45957053 TESK2 0.45 5.86 0.3 1.07e-8 High light scatter reticulocyte count; LIHC cis rs10876993 0.890 rs1689584 chr12:58081478 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.14 -0.32 2.25e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs7909074 0.831 rs11239271 chr10:45376294 A/G cg04218760 chr10:45406644 TMEM72 -0.25 -7.77 -0.39 9.36e-14 Mean corpuscular volume; LIHC cis rs16912285 0.688 rs11827298 chr11:24324000 G/A ch.11.24196551F chr11:24239977 NA 0.76 10.02 0.48 6.8e-21 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25047243 chr2:32502969 YIPF4 -0.46 -6.12 -0.31 2.63e-9 Systolic blood pressure; LIHC cis rs801193 0.569 rs881285 chr7:66119420 A/G cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs10197940 0.578 rs6718653 chr2:152346118 C/A cg19508488 chr2:152266495 RIF1 0.48 6.8 0.35 4.58e-11 Lung cancer; LIHC cis rs12824058 0.831 rs12320318 chr12:130812335 T/C cg24838063 chr12:130822603 PIWIL1 0.67 9.86 0.47 2.31e-20 Menopause (age at onset); LIHC cis rs68170813 0.641 rs79328953 chr7:106901557 C/T cg02696742 chr7:106810147 HBP1 -0.53 -6.23 -0.32 1.38e-9 Coronary artery disease; LIHC cis rs2549003 0.933 rs3846731 chr5:131814264 T/C cg02551604 chr5:131831745 NA -0.43 -6.52 -0.33 2.51e-10 Asthma (sex interaction); LIHC cis rs67478160 0.654 rs11628240 chr14:104218135 A/G cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.61 -0.38 2.66e-13 Schizophrenia; LIHC cis rs17685 0.671 rs10274404 chr7:75706634 G/A cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.56e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1371867 0.846 rs1788191 chr8:101260844 C/T cg06002616 chr8:101225028 SPAG1 0.34 5.84 0.3 1.2e-8 Atrioventricular conduction; LIHC cis rs12188164 0.543 rs7728027 chr5:459943 T/C cg24955955 chr5:415729 AHRR 0.32 6.63 0.34 1.28e-10 Cystic fibrosis severity; LIHC cis rs10779751 0.770 rs1417131 chr1:11191922 T/C cg08854313 chr1:11322531 MTOR -0.76 -9.67 -0.46 1.03e-19 Body mass index; LIHC cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.41 0.45 7.44e-19 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20273774 chr5:180671298 GNB2L1;SNORD95 0.47 7.14 0.36 5.53e-12 Cognitive function; LIHC cis rs9902453 0.765 rs6505143 chr17:28150585 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.82 14.03 0.6 1.22e-35 Coffee consumption (cups per day); LIHC cis rs3784262 0.692 rs4646590 chr15:58303137 C/T cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.73 -0.3 2.21e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg25894440 chr7:65020034 NA -0.56 -6.39 -0.33 5.3e-10 Diabetic kidney disease; LIHC cis rs6546550 0.900 rs2054047 chr2:70117421 A/C cg02498382 chr2:70120550 SNRNP27 -0.42 -7.0 -0.35 1.32e-11 Prevalent atrial fibrillation; LIHC cis rs703842 0.616 rs4760332 chr12:58222672 A/C cg04478727 chr12:58166393 METTL1;FAM119B -0.72 -10.09 -0.48 3.9e-21 Multiple sclerosis; LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs9811920 0.638 rs793461 chr3:99615758 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs7238033 0.624 rs7229967 chr18:43312368 C/T cg20610511 chr18:43302872 SLC14A1 0.37 6.18 0.32 1.83e-9 Bladder cancer; LIHC cis rs10489202 0.608 rs3753934 chr1:168074677 C/T cg24449463 chr1:168025552 DCAF6 -0.55 -8.36 -0.41 1.61e-15 Schizophrenia; LIHC cis rs17376456 0.825 rs17374166 chr5:93238655 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs875971 0.929 rs12535036 chr7:65964063 G/T cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.64e-11 Aortic root size; LIHC cis rs1878931 0.582 rs27231 chr16:3434966 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.67 8.87 0.43 4.29e-17 Body mass index (adult); LIHC cis rs11098499 0.697 rs10016448 chr4:120298845 A/G cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs546131 0.642 rs568529 chr11:34842506 C/A cg11058730 chr11:34937778 PDHX;APIP 0.64 9.37 0.45 1e-18 Lung disease severity in cystic fibrosis; LIHC cis rs6840360 1.000 rs4696109 chr4:152668785 A/C cg22705602 chr4:152727874 NA -0.34 -7.21 -0.36 3.7e-12 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs13106338 chr4:17676871 G/T cg16339924 chr4:17578868 LAP3 -0.47 -6.25 -0.32 1.22e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 9.22 0.45 3.2e-18 Platelet count; LIHC cis rs1707322 1.000 rs2458400 chr1:46530798 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.68 -0.34 9.69e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs11098499 0.908 rs2017057 chr4:120257711 A/G cg25214090 chr10:38739885 LOC399744 0.56 8.98 0.44 1.88e-17 Corneal astigmatism; LIHC cis rs2979489 0.891 rs7822839 chr8:30354453 A/G cg26383811 chr8:30366931 RBPMS 0.75 12.14 0.55 1.85e-28 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC trans rs11098499 0.909 rs1546504 chr4:120241179 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.59 0.46 1.84e-19 Corneal astigmatism; LIHC cis rs7131987 0.903 rs67517901 chr12:29421346 A/G cg12903224 chr12:29470962 FAR2 -0.42 -6.81 -0.35 4.43e-11 QT interval; LIHC cis rs1707322 0.721 rs6697821 chr1:46216722 A/G cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg10755058 chr3:40428713 ENTPD3 0.39 6.6 0.34 1.61e-10 Renal cell carcinoma; LIHC cis rs2304069 0.659 rs216141 chr5:149443994 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.56 -7.58 -0.38 3.34e-13 HIV-1 control; LIHC cis rs644799 0.544 rs687559 chr11:95598629 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.6 -9.26 -0.45 2.32e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9457247 0.602 rs12209395 chr6:167463914 C/T cg12798992 chr6:167411361 FGFR1OP 0.45 6.69 0.34 9.06e-11 Crohn's disease; LIHC cis rs7091068 0.706 rs4919398 chr10:95429162 C/T cg20715218 chr10:95462985 C10orf4 0.57 6.17 0.32 1.91e-9 Urinary tract infection frequency; LIHC cis rs9309711 0.544 rs9309712 chr2:3491327 G/T cg15506890 chr2:3487001 NA -0.47 -7.34 -0.37 1.61e-12 Neurofibrillary tangles; LIHC trans rs4906332 1.000 rs35224956 chr14:103900481 A/G cg17675199 chr6:35436792 RPL10A 0.32 6.37 0.33 6.25e-10 Coronary artery disease; LIHC cis rs9486715 0.838 rs9386576 chr6:96954717 C/T cg06623918 chr6:96969491 KIAA0776 0.86 15.21 0.64 2.93e-40 Headache; LIHC cis rs2412488 0.893 rs12642403 chr4:54361640 A/G cg22241045 chr4:54363911 LNX1 -0.45 -7.62 -0.38 2.57e-13 DNA methylation (variation); LIHC cis rs9733 0.596 rs6587516 chr1:150623221 C/T cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.46 0.62 2.59e-37 Prudent dietary pattern; LIHC cis rs9303280 0.901 rs883770 chr17:38063381 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.9 0.3 8.79e-9 Self-reported allergy; LIHC cis rs722599 0.715 rs61978928 chr14:75321714 T/C cg11812906 chr14:75593930 NEK9 -0.4 -5.97 -0.31 5.95e-9 IgG glycosylation; LIHC cis rs826838 1.000 rs10880826 chr12:38672787 G/C cg13010199 chr12:38710504 ALG10B 0.64 7.57 0.38 3.57e-13 Heart rate; LIHC cis rs6076065 0.748 rs6048779 chr20:23374709 C/G cg11657817 chr20:23433608 CST11 0.33 7.05 0.36 9.97e-12 Facial morphology (factor 15, philtrum width); LIHC cis rs1008375 1.000 rs3815413 chr4:17654648 T/C cg02297831 chr4:17616191 MED28 0.51 7.86 0.39 5.16e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7818688 0.697 rs11778553 chr8:95978260 C/T cg16049864 chr8:95962084 TP53INP1 0.56 6.08 0.31 3.21e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs12477438 1.000 rs12053372 chr2:99810055 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.94 -10.85 -0.51 9.04e-24 Chronic sinus infection; LIHC cis rs7772486 0.806 rs2253648 chr6:146199296 G/A cg05347473 chr6:146136440 FBXO30 0.36 6.15 0.32 2.14e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1003719 0.667 rs8127148 chr21:38481292 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.75 11.64 0.53 1.31e-26 Eye color traits; LIHC cis rs7552404 0.921 rs10873685 chr1:76218818 A/C cg10523679 chr1:76189770 ACADM 0.64 8.74 0.43 1.08e-16 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs9929218 0.551 rs1886697 chr16:68716179 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.92 22.14 0.77 5.17e-68 Colorectal cancer; LIHC cis rs2153535 0.521 rs6939827 chr6:8461360 C/G cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.21e-26 Motion sickness; LIHC cis rs3736485 0.932 rs2278990 chr15:51914662 G/A cg08986416 chr15:51914746 DMXL2 -0.47 -7.01 -0.35 1.28e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7000551 0.689 rs6984908 chr8:22316901 A/G cg12081754 chr8:22256438 SLC39A14 -0.53 -8.59 -0.42 3.12e-16 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.37 0.41 1.55e-15 Platelet count; LIHC cis rs7927592 0.913 rs10896346 chr11:68352671 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.22 -0.32 1.46e-9 Total body bone mineral density; LIHC cis rs12477438 0.520 rs7605843 chr2:99811894 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.86 15.05 0.63 1.26e-39 Chronic sinus infection; LIHC cis rs2979489 0.945 rs11993146 chr8:30319537 G/A cg26383811 chr8:30366931 RBPMS -0.75 -13.22 -0.58 1.69e-32 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs10949834 0.824 rs3801461 chr7:73536368 C/G cg07137043 chr7:73588983 EIF4H -0.61 -6.04 -0.31 3.98e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs7662987 0.517 rs2602845 chr4:100023944 T/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg27170947 chr2:26402098 FAM59B -0.68 -8.4 -0.41 1.19e-15 Gut microbiome composition (summer); LIHC cis rs6596100 0.538 rs34592321 chr5:132181675 G/C cg02081065 chr5:132209139 LEAP2 0.29 6.28 0.32 1.05e-9 Breast cancer; LIHC cis rs2617583 0.967 rs2617595 chr5:1448246 C/T cg07151155 chr5:1473589 LPCAT1 -0.4 -6.15 -0.32 2.18e-9 Breast cancer; LIHC cis rs12586317 0.582 rs731906 chr14:35604543 C/T cg16230307 chr14:35515116 FAM177A1 0.78 13.01 0.58 1.03e-31 Psoriasis; LIHC cis rs12702595 0.936 rs6960832 chr7:7267787 G/T cg04827551 chr7:7268805 C1GALT1 0.39 7.07 0.36 8.94e-12 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs12586317 0.620 rs8020370 chr14:35581432 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.17 0.58 2.51e-32 Psoriasis; LIHC cis rs1008375 0.797 rs6843530 chr4:17593605 G/T cg16339924 chr4:17578868 LAP3 0.46 6.43 0.33 4.32e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1144333 1.000 rs12082448 chr1:76353225 C/T cg03433033 chr1:76189801 ACADM 0.57 8.59 0.42 3.18e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs144345632 1 rs144345632 chr6:96886894 T/TA cg06623918 chr6:96969491 KIAA0776 -0.71 -7.06 -0.36 9.32e-12 Facial morphology (factor 17, height of vermillion upper lip); LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.07 0.4 1.23e-14 Height; LIHC trans rs7618501 0.521 rs11709573 chr3:49956628 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.79 0.34 4.93e-11 Intelligence (multi-trait analysis); LIHC cis rs1163251 0.902 rs487081 chr1:120217389 G/A cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.21 -0.32 1.56e-9 Diastolic blood pressure; LIHC cis rs56104184 0.723 rs116909499 chr19:49407733 C/T cg21252483 chr19:49399788 TULP2 -1.0 -11.73 -0.54 6.22e-27 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs12135062 0.901 rs2651928 chr1:3101722 C/T cg21609526 chr1:3105151 PRDM16 -0.29 -6.58 -0.34 1.73e-10 Migraine; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg26338869 chr17:61819248 STRADA 0.61 8.84 0.43 5.21e-17 Prudent dietary pattern; LIHC cis rs853679 0.517 rs35512245 chr6:28079953 T/C cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs10411936 0.924 rs8110761 chr19:16501005 A/G cg10248733 chr19:16607483 C19orf44;CALR3 0.43 5.89 0.3 9.26e-9 White blood cell count;Multiple sclerosis; LIHC cis rs875971 0.638 rs3898855 chr7:66036398 G/C cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs7582720 1.000 rs72932558 chr2:203847325 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2243480 1.000 rs160643 chr7:65558222 C/T cg07424592 chr7:64974309 NA 0.68 8.19 0.4 5.43e-15 Diabetic kidney disease; LIHC cis rs265548 0.646 rs36689 chr19:17910639 A/G cg21960279 chr19:17905606 B3GNT3 0.53 8.36 0.41 1.63e-15 Tumor biomarkers; LIHC cis rs9486719 1.000 rs3798295 chr6:97052164 C/T cg18709589 chr6:96969512 KIAA0776 -0.5 -6.04 -0.31 4.03e-9 Migraine;Coronary artery disease; LIHC cis rs9916302 0.706 rs584377 chr17:37460128 G/A cg07936489 chr17:37558343 FBXL20 0.84 12.14 0.55 1.84e-28 Glomerular filtration rate (creatinine); LIHC cis rs9929218 1.000 rs9937664 chr16:68784603 T/C cg01231543 chr16:68741748 NA 0.37 5.76 0.3 1.86e-8 Colorectal cancer; LIHC cis rs7072216 0.621 rs3750605 chr10:100175654 C/T cg26618903 chr10:100175079 PYROXD2 -0.38 -5.74 -0.3 2.1e-8 Metabolite levels; LIHC cis rs3812831 0.654 rs367312 chr13:114930195 G/A cg06611532 chr13:114900021 NA 0.38 6.91 0.35 2.42e-11 Schizophrenia; LIHC cis rs2953145 0.545 rs2975755 chr2:241524919 G/A cg07929629 chr2:241523174 NA 0.65 9.5 0.46 3.67e-19 Bipolar disorder; LIHC cis rs12887734 0.566 rs3742366 chr14:104198351 T/C cg24130564 chr14:104152367 KLC1 -0.41 -6.65 -0.34 1.19e-10 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2845885 1.000 rs11231698 chr11:63877163 C/T cg18375707 chr11:64034959 PLCB3 -0.44 -5.83 -0.3 1.29e-8 Body mass index; LIHC cis rs1555322 0.530 rs7004 chr20:33866753 G/C cg07134254 chr20:33865797 NA 0.53 6.23 0.32 1.36e-9 Attention deficit hyperactivity disorder; LIHC cis rs921968 0.643 rs598701 chr2:219387005 C/G cg02985541 chr2:219472218 PLCD4 -0.43 -8.04 -0.4 1.53e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg02290350 chr8:58132656 NA 0.44 8.59 0.42 3.22e-16 Developmental language disorder (linguistic errors); LIHC cis rs4671458 0.724 rs56219461 chr2:63669666 G/A cg17519650 chr2:63277830 OTX1 -0.57 -6.57 -0.33 1.87e-10 Subjective well-being; LIHC cis rs9816226 1.000 rs61587156 chr3:185831583 T/G cg00760338 chr3:185826511 ETV5 -0.7 -6.34 -0.32 7.2e-10 Obesity;Body mass index; LIHC cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg21448741 chr8:58168803 NA 0.37 5.95 0.31 6.81e-9 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.563 rs7739249 chr6:8534590 C/G cg21535247 chr6:8435926 SLC35B3 0.62 8.31 0.41 2.32e-15 Motion sickness; LIHC cis rs10197940 0.753 rs2290368 chr2:152266473 T/C cg19508488 chr2:152266495 RIF1 0.74 12.56 0.56 4.98e-30 Lung cancer; LIHC trans rs2749592 0.531 rs994804 chr10:37900140 A/C cg27523141 chr10:43048294 ZNF37B -0.37 -6.3 -0.32 8.92e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9486719 0.947 rs2472893 chr6:96870048 G/C cg06623918 chr6:96969491 KIAA0776 0.74 7.29 0.37 2.22e-12 Migraine;Coronary artery disease; LIHC cis rs908922 0.676 rs2282296 chr1:152487979 C/T cg23254163 chr1:152506842 NA 0.22 5.79 0.3 1.64e-8 Hair morphology; LIHC cis rs5770917 1.000 rs3213445 chr22:51015838 T/C cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.42 -6.06 -0.31 3.57e-9 Narcolepsy; LIHC cis rs4970966 0.855 rs11204701 chr1:150662179 A/T cg17724175 chr1:150552817 MCL1 -0.37 -5.97 -0.31 6.03e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs12893668 0.667 rs8017628 chr14:104047428 C/T cg19000871 chr14:103996768 TRMT61A -0.42 -7.04 -0.36 1.08e-11 Reticulocyte count; LIHC cis rs9640161 0.659 rs7806429 chr7:150013393 A/G cg10018233 chr7:150070692 REPIN1 0.5 8.47 0.42 7.54e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs7224685 0.569 rs12453798 chr17:4017079 C/T cg11204139 chr17:3907470 NA 0.59 6.67 0.34 1.01e-10 Type 2 diabetes; LIHC cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg16606324 chr3:10149918 C3orf24 0.54 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.42 5.93 0.31 7.51e-9 Electroencephalogram traits; LIHC cis rs12478296 1.000 rs113129906 chr2:243004253 C/T cg18898632 chr2:242989856 NA -0.69 -8.75 -0.43 9.88e-17 Obesity-related traits; LIHC cis rs7769051 1.000 rs6934161 chr6:133124077 C/T cg07930552 chr6:133119739 C6orf192 -0.7 -6.78 -0.34 5.31e-11 Type 2 diabetes nephropathy; LIHC cis rs7520050 0.966 rs12561806 chr1:46396776 C/T cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1789 0.903 rs4616746 chr4:15673098 A/G cg21123203 chr4:15471301 CC2D2A -0.43 -6.78 -0.34 5.25e-11 Blood protein levels; LIHC cis rs826838 0.935 rs11183940 chr12:38851642 A/G cg26384229 chr12:38710491 ALG10B 0.98 13.29 0.58 8.46e-33 Heart rate; LIHC cis rs6570726 0.764 rs9403731 chr6:145907937 G/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.83 -0.3 1.29e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs35306767 0.855 rs34318754 chr10:890714 G/A cg20503657 chr10:835505 NA 1.35 14.76 0.62 1.75e-38 Eosinophil percentage of granulocytes; LIHC cis rs79149102 0.579 rs7342601 chr15:75306795 G/T cg15902774 chr15:75289873 SCAMP5 -0.41 -6.36 -0.33 6.61e-10 Lung cancer; LIHC cis rs703842 0.739 rs701008 chr12:58117645 A/G cg18357645 chr12:58087776 OS9 -0.47 -7.66 -0.38 1.88e-13 Multiple sclerosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06625838 chr5:162865006 CCNG1 0.45 6.93 0.35 2.08e-11 Cognitive function; LIHC cis rs7772486 0.658 rs9403737 chr6:145962193 G/T cg13319975 chr6:146136371 FBXO30 -0.36 -5.95 -0.31 6.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1816752 0.870 rs2033955 chr13:25010544 T/C cg02811702 chr13:24901961 NA 0.25 6.33 0.32 7.79e-10 Obesity-related traits; LIHC cis rs2130392 0.926 rs7679215 chr4:185635311 C/T cg21366198 chr4:185655624 MLF1IP 0.53 8.44 0.42 9.3e-16 Kawasaki disease; LIHC cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg11062466 chr8:58055876 NA 0.5 6.31 0.32 8.66e-10 Developmental language disorder (linguistic errors); LIHC cis rs2066819 1.000 rs59295315 chr12:56708576 G/A cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs6942756 1.000 rs7778277 chr7:128978805 C/T cg02491457 chr7:128862824 NA -0.61 -8.9 -0.43 3.41e-17 White matter hyperintensity burden; LIHC cis rs7607369 0.719 rs7567622 chr2:219624549 A/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg15691649 chr6:25882328 NA -0.94 -14.41 -0.61 3.92e-37 Uric acid levels; LIHC cis rs7647973 0.769 rs7434187 chr3:49032967 C/T cg07636037 chr3:49044803 WDR6 0.76 9.06 0.44 1.02e-17 Menarche (age at onset); LIHC cis rs116095464 0.510 rs7723883 chr5:270798 T/C cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 7.43 0.37 9.02e-13 Platelet count; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg04267008 chr7:1944627 MAD1L1 0.62 9.93 0.47 1.42e-20 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs9393025 chr6:8490618 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18176703 chr3:115503520 NA -0.42 -6.07 -0.31 3.36e-9 Longevity; LIHC cis rs9457247 0.663 rs9457257 chr6:167440736 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.73 -0.43 1.13e-16 Crohn's disease; LIHC trans rs7615952 0.604 rs9837847 chr3:125623919 G/A cg07211511 chr3:129823064 LOC729375 -0.82 -8.7 -0.43 1.47e-16 Blood pressure (smoking interaction); LIHC cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.82 -12.74 -0.57 1.1e-30 Total body bone mineral density; LIHC cis rs6088813 1.000 rs6142376 chr20:33992761 T/A cg14752227 chr20:34000481 UQCC -0.41 -5.88 -0.3 9.69e-9 Height; LIHC cis rs4820294 1.000 rs78974622 chr22:38059925 A/C cg00142150 chr22:38071001 LGALS1 0.7 11.36 0.52 1.42e-25 Fat distribution (HIV); LIHC cis rs2730245 0.550 rs2657364 chr7:158683825 T/C cg23730037 chr7:158596552 ESYT2 -0.43 -6.63 -0.34 1.3e-10 Height; LIHC cis rs6138458 0.701 rs6050255 chr20:25007089 A/G cg26195577 chr20:24973756 C20orf3 0.83 10.73 0.5 2.48e-23 Blood protein levels; LIHC cis rs943466 1.000 rs6933607 chr6:33743997 G/A cg25922239 chr6:33757077 LEMD2 -0.47 -5.77 -0.3 1.75e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs10751667 0.643 rs10902237 chr11:944801 C/A cg06064525 chr11:970664 AP2A2 -0.55 -14.87 -0.63 6.52e-39 Alzheimer's disease (late onset); LIHC cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg16262614 chr3:133464971 TF 0.28 6.28 0.32 1.01e-9 Iron status biomarkers; LIHC cis rs13108904 0.539 rs13140926 chr4:1340939 G/A cg00684032 chr4:1343700 KIAA1530 0.59 8.51 0.42 5.51e-16 Obesity-related traits; LIHC cis rs599083 0.530 rs576118 chr11:68177708 C/T cg01657329 chr11:68192670 LRP5 0.57 7.74 0.39 1.11e-13 Bone mineral density (spine); LIHC cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 6.01 0.31 4.84e-9 Schizophrenia; LIHC cis rs7249142 0.549 rs10854012 chr19:19295719 C/T cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.34 -5.71 -0.3 2.44e-8 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01153342 chr14:74254319 C14orf43 0.47 7.6 0.38 2.88e-13 Cognitive function; LIHC cis rs7107174 1.000 rs72931642 chr11:78037862 A/T cg02023728 chr11:77925099 USP35 0.5 9.49 0.46 4.03e-19 Testicular germ cell tumor; LIHC cis rs7296418 0.961 rs11608811 chr12:123529056 A/G cg06742321 chr12:123595122 PITPNM2 0.31 5.9 0.3 8.99e-9 Platelet count; LIHC cis rs35110281 0.774 rs1003280 chr21:44997322 A/G cg21573476 chr21:45109991 RRP1B -0.53 -9.93 -0.47 1.42e-20 Mean corpuscular volume; LIHC cis rs5758511 0.680 rs5758667 chr22:42633204 G/A cg00645731 chr22:42541494 CYP2D7P1 0.53 8.44 0.42 8.99e-16 Birth weight; LIHC cis rs1163251 0.902 rs640195 chr1:120217650 T/A cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC cis rs4927850 0.709 rs6783079 chr3:195652708 T/C cg12923728 chr3:195709715 SDHAP1 -0.61 -6.2 -0.32 1.62e-9 Pancreatic cancer; LIHC cis rs3824867 0.920 rs9919526 chr11:47451623 C/T cg20307385 chr11:47447363 PSMC3 -0.58 -7.85 -0.39 5.45e-14 Mean corpuscular hemoglobin; LIHC trans rs983392 0.709 rs1426250 chr11:60001325 A/G cg17275991 chr19:58003312 ZNF419 0.43 6.13 0.31 2.45e-9 Alzheimer's disease (late onset); LIHC trans rs11098499 0.874 rs13139045 chr4:120168588 T/C cg25214090 chr10:38739885 LOC399744 0.43 6.62 0.34 1.37e-10 Corneal astigmatism; LIHC cis rs4919087 0.683 rs7091162 chr10:99071242 G/T cg25902810 chr10:99078978 FRAT1 -0.6 -7.23 -0.36 3.16e-12 Monocyte count; LIHC cis rs1448094 0.512 rs11503595 chr12:86244075 T/A cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.24e-10 Major depressive disorder; LIHC trans rs116095464 0.542 rs28650039 chr5:273954 C/A cg00938859 chr5:1591904 SDHAP3 0.52 6.41 0.33 4.8e-10 Breast cancer; LIHC cis rs11608355 0.545 rs1073779 chr12:109894721 C/T cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs8114671 0.562 rs6120763 chr20:33506400 C/G cg07148914 chr20:33460835 GGT7 0.65 9.86 0.47 2.42e-20 Height; LIHC cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg13393036 chr8:95962371 TP53INP1 -0.38 -8.97 -0.44 1.99e-17 Type 2 diabetes; LIHC cis rs2549003 0.966 rs2706385 chr5:131831766 T/G cg02551604 chr5:131831745 NA 0.47 7.24 0.36 2.98e-12 Asthma (sex interaction); LIHC cis rs881375 0.678 rs10760129 chr9:123700183 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.75 0.34 6.4e-11 Rheumatoid arthritis; LIHC cis rs13272623 0.502 rs268601 chr8:71518548 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.43 -5.76 -0.3 1.89e-8 IgG glycosylation; LIHC cis rs250677 0.652 rs36042 chr5:148439782 G/T cg18129178 chr5:148520854 ABLIM3 -0.55 -7.05 -0.36 1.03e-11 Breast cancer; LIHC cis rs9911578 0.835 rs9788975 chr17:56460800 G/A cg05425664 chr17:57184151 TRIM37 0.56 8.14 0.4 7.48e-15 Intelligence (multi-trait analysis); LIHC cis rs17253792 0.545 rs35536987 chr14:56024021 A/G cg01858014 chr14:56050164 KTN1 -0.67 -6.11 -0.31 2.74e-9 Putamen volume; LIHC cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg03264133 chr6:25882463 NA -0.6 -8.47 -0.42 7.25e-16 Blood metabolite levels; LIHC cis rs12095069 1 rs12095069 chr1:76463072 T/C cg10523679 chr1:76189770 ACADM 0.42 5.96 0.31 6.4e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs8192917 1.000 rs6573911 chr14:25100933 A/G cg03875678 chr14:25103546 GZMB -0.4 -7.15 -0.36 5.2e-12 Vitiligo; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs72627123 0.737 rs61475846 chr14:74485781 T/C cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 6.02 0.31 4.59e-9 Morning vs. evening chronotype; LIHC trans rs57221529 0.766 rs12521051 chr5:560440 A/G cg25482853 chr8:67687455 SGK3 -0.66 -6.65 -0.34 1.15e-10 Lung disease severity in cystic fibrosis; LIHC cis rs6952808 0.743 rs10266703 chr7:1918941 C/A cg04267008 chr7:1944627 MAD1L1 -0.57 -8.4 -0.41 1.21e-15 Bipolar disorder and schizophrenia; LIHC cis rs427394 0.659 rs274693 chr5:6734162 G/A cg10857441 chr5:6722123 POLS -0.39 -6.51 -0.33 2.65e-10 Menopause (age at onset); LIHC cis rs2274273 0.837 rs6573017 chr14:55802243 G/A cg01864836 chr14:55583639 NA -0.4 -7.48 -0.38 6.21e-13 Protein biomarker; LIHC cis rs7582180 0.764 rs1530028 chr2:100927910 A/C cg14675211 chr2:100938903 LONRF2 0.53 8.28 0.41 2.83e-15 Intelligence (multi-trait analysis); LIHC cis rs9910055 0.530 rs2269907 chr17:42294215 G/A cg08499158 chr17:42289980 UBTF -0.48 -7.81 -0.39 7.16e-14 Total body bone mineral density; LIHC cis rs965469 0.779 rs6515810 chr20:3370861 T/C cg25506879 chr20:3388711 C20orf194 -0.52 -6.34 -0.32 7.07e-10 IFN-related cytopenia; LIHC cis rs523522 0.847 rs11065132 chr12:120908459 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.85 0.54 2.18e-27 High light scatter reticulocyte count; LIHC cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg08645402 chr16:4508243 NA 0.4 7.15 0.36 5.3e-12 Schizophrenia; LIHC cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.26 -0.61 1.62e-36 Alzheimer's disease; LIHC cis rs7100689 0.784 rs7082705 chr10:82170856 C/T cg00277334 chr10:82204260 NA 0.6 7.84 0.39 5.8e-14 Post bronchodilator FEV1; LIHC cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg25894440 chr7:65020034 NA -0.54 -6.27 -0.32 1.08e-9 Diabetic kidney disease; LIHC cis rs2295359 0.892 rs56920441 chr1:67652012 A/G cg12940439 chr1:67600707 NA 0.34 5.94 0.31 6.86e-9 Psoriasis; LIHC cis rs11966931 0.711 rs9320236 chr6:108089688 G/T cg04749840 chr6:108095067 SCML4 -0.37 -6.65 -0.34 1.17e-10 Neutrophil percentage of white cells; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg12016809 chr21:47604291 C21orf56 -0.47 -7.32 -0.37 1.75e-12 Testicular germ cell tumor; LIHC trans rs2744203 1.000 rs72610888 chr6:104655184 C/T cg27088726 chr16:83171155 CDH13 -0.45 -6.07 -0.31 3.35e-9 IgG glycosylation; LIHC cis rs6061231 1.000 rs11908473 chr20:60957770 C/G cg24112000 chr20:60950667 NA -0.63 -9.58 -0.46 2.14e-19 Colorectal cancer; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg00280220 chr17:61926910 NA 0.44 7.15 0.36 5.34e-12 Prudent dietary pattern; LIHC cis rs35883536 1.000 rs1932351 chr1:101142049 C/T cg14515779 chr1:101123966 NA -0.69 -13.84 -0.6 6.8000000000000005e-35 Monocyte count; LIHC cis rs6456156 0.565 rs12529238 chr6:167465576 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.68 -0.42 1.69e-16 Primary biliary cholangitis; LIHC cis rs11098499 0.863 rs3822191 chr4:120428101 A/T cg09307838 chr4:120376055 NA 0.76 11.62 0.53 1.52e-26 Corneal astigmatism; LIHC cis rs1113500 0.787 rs4571989 chr1:108631344 G/A cg06207961 chr1:108661230 NA 0.31 5.93 0.31 7.41e-9 Growth-regulated protein alpha levels; LIHC trans rs9747201 0.963 rs4789729 chr17:80146089 G/A cg07393940 chr7:158741817 NA 0.56 6.66 0.34 1.06e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs916888 0.773 rs199451 chr17:44801784 G/A cg16836995 chr17:43662488 NA -0.76 -7.78 -0.39 8.38e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1707322 0.789 rs10789473 chr1:46248131 C/T cg03146154 chr1:46216737 IPP 0.52 8.61 0.42 2.75e-16 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7572733 0.555 rs11889006 chr2:198928647 A/G cg00792783 chr2:198669748 PLCL1 0.4 5.76 0.3 1.86e-8 Dermatomyositis; LIHC cis rs6545883 0.965 rs2305156 chr2:61729268 T/C cg14146966 chr2:61757674 XPO1 0.47 8.25 0.41 3.46e-15 Tuberculosis; LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg20887711 chr4:1340912 KIAA1530 0.8 12.59 0.56 4.04e-30 Longevity; LIHC cis rs9486715 0.867 rs2475025 chr6:96988696 A/T cg18709589 chr6:96969512 KIAA0776 -0.33 -5.83 -0.3 1.32e-8 Headache; LIHC cis rs748404 0.631 rs8042688 chr15:43638525 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.86 0.43 4.31e-17 Lung cancer; LIHC cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.522 rs289649 chr10:37975384 T/C cg17830980 chr10:43048298 ZNF37B -0.43 -8.21 -0.41 4.73e-15 Extrinsic epigenetic age acceleration; LIHC cis rs2404602 0.532 rs206205 chr15:76736091 T/G cg23625390 chr15:77176239 SCAPER 0.41 6.92 0.35 2.3e-11 Blood metabolite levels; LIHC cis rs67311347 0.524 rs11129869 chr3:40259738 G/A cg18306943 chr3:40428807 ENTPD3 0.38 6.33 0.32 7.63e-10 Renal cell carcinoma; LIHC cis rs11628318 0.614 rs12588817 chr14:103089210 G/A cg01864069 chr14:103024347 NA -0.34 -5.76 -0.3 1.83e-8 Platelet count; LIHC cis rs2576037 0.526 rs4258717 chr18:44456954 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.73e-12 Personality dimensions; LIHC cis rs2836950 0.509 rs4816618 chr21:40599529 G/A cg11890956 chr21:40555474 PSMG1 -0.46 -7.37 -0.37 1.32e-12 Menarche (age at onset); LIHC cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg12310025 chr6:25882481 NA -0.61 -8.56 -0.42 3.9e-16 Blood metabolite levels; LIHC cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg01206211 chr2:36825736 FEZ2 0.43 7.02 0.35 1.21e-11 Height; LIHC cis rs2228479 0.850 rs2190808 chr16:89840856 C/T cg19635926 chr16:89946313 TCF25 0.5 6.48 0.33 3.24e-10 Skin colour saturation; LIHC cis rs79149102 0.737 rs16973172 chr15:75156944 G/A cg16226627 chr15:75307476 SCAMP5 0.44 6.13 0.31 2.45e-9 Lung cancer; LIHC cis rs13191362 0.935 rs13215748 chr6:163010710 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7520050 0.966 rs9429183 chr1:46524582 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.85 0.3 1.18e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2404602 0.536 rs11072599 chr15:76774508 T/C cg03037974 chr15:76606532 NA 0.76 14.76 0.62 1.78e-38 Blood metabolite levels; LIHC cis rs6545883 0.899 rs12473030 chr2:61720497 T/A cg14146966 chr2:61757674 XPO1 0.47 8.16 0.4 6.3e-15 Tuberculosis; LIHC cis rs9640161 0.742 rs2108853 chr7:150017589 A/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.23 -0.41 4.01e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs10751667 0.666 rs6597966 chr11:950750 T/C cg10932868 chr11:921992 NA 0.39 7.29 0.37 2.22e-12 Alzheimer's disease (late onset); LIHC cis rs2153535 0.580 rs2327058 chr6:8447018 C/T cg23788917 chr6:8435910 SLC35B3 0.62 8.84 0.43 5.15e-17 Motion sickness; LIHC trans rs1814175 0.587 rs7937757 chr11:49978342 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs2273156 1.000 rs12880809 chr14:35475656 A/G cg16230307 chr14:35515116 FAM177A1 -0.41 -6.05 -0.31 3.88e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs7119038 0.818 rs56758835 chr11:118615340 G/A cg19308663 chr11:118741387 NA 0.43 5.79 0.3 1.56e-8 Sjögren's syndrome; LIHC cis rs763121 0.853 rs5750652 chr22:39048316 A/G cg06022373 chr22:39101656 GTPBP1 0.75 15.23 0.64 2.5e-40 Menopause (age at onset); LIHC cis rs16866061 1.000 rs4674916 chr2:225365635 C/A cg12698349 chr2:225449008 CUL3 0.8 14.1 0.61 6.78e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs155076 1.000 rs598754 chr13:21845010 C/A cg11317459 chr13:21872234 NA -1.17 -13.06 -0.58 6.87e-32 White matter hyperintensity burden; LIHC cis rs3749237 0.595 rs35701831 chr3:49515000 A/C cg03060546 chr3:49711283 APEH 0.59 9.74 0.47 5.94e-20 Resting heart rate; LIHC cis rs10540 0.841 rs35601764 chr11:532923 A/C cg03352830 chr11:487213 PTDSS2 0.8 6.45 0.33 3.76e-10 Body mass index; LIHC cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.88 7.96 0.4 2.52e-14 Platelet count; LIHC cis rs1005277 0.579 rs2474586 chr10:38418882 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.38 -0.56 2.36e-29 Extrinsic epigenetic age acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18710692 chr13:20437712 ZMYM5 -0.48 -6.6 -0.34 1.55e-10 Longevity; LIHC cis rs11792861 0.926 rs7856626 chr9:111775502 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.62 0.42 2.46e-16 Menarche (age at onset); LIHC cis rs600806 0.850 rs3931560 chr1:109966718 A/C cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.54 -0.38 4.39e-13 Intelligence (multi-trait analysis); LIHC cis rs600806 0.854 rs11142 chr1:109897103 A/G cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.9 -0.3 8.68e-9 Intelligence (multi-trait analysis); LIHC cis rs9486719 1.000 rs11153064 chr6:97021959 A/G cg06623918 chr6:96969491 KIAA0776 -0.7 -7.21 -0.36 3.53e-12 Migraine;Coronary artery disease; LIHC cis rs7582180 0.627 rs4851312 chr2:101011241 G/A cg14675211 chr2:100938903 LONRF2 0.56 8.23 0.41 3.98e-15 Intelligence (multi-trait analysis); LIHC cis rs67981189 0.593 rs2526883 chr14:71369575 T/G cg15816911 chr14:71606274 NA -0.4 -6.47 -0.33 3.4e-10 Schizophrenia; LIHC cis rs10911232 0.560 rs6697320 chr1:183037377 T/G ch.1.3577855R chr1:183094577 LAMC1 0.57 9.84 0.47 2.86e-20 Hypertriglyceridemia; LIHC cis rs3806843 0.933 rs2337987 chr5:140188383 T/G cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs13191362 0.935 rs67368176 chr6:162968436 A/T cg06582575 chr6:163149167 PACRG;PARK2 0.72 5.86 0.3 1.11e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg25072359 chr17:41440525 NA 0.37 5.95 0.31 6.5e-9 Menopause (age at onset); LIHC cis rs4803468 1.000 rs1043413 chr19:41939297 C/G cg09537434 chr19:41945824 ATP5SL 1.01 20.22 0.74 2.4e-60 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25340675 chr3:121468720 GOLGB1 -0.49 -6.43 -0.33 4.2e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg21167532 chr1:33231272 KIAA1522 0.37 6.38 0.33 5.86e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7216064 0.953 rs75231441 chr17:65885485 A/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.35 -0.45 1.16e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7246657 0.943 rs10413602 chr19:37891492 T/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs7551222 0.789 rs4951408 chr1:204558984 C/G cg20240347 chr1:204465584 NA -0.33 -6.72 -0.34 7.72e-11 Schizophrenia; LIHC cis rs2576037 0.583 rs593340 chr18:44418346 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -7.06 -0.36 9.1e-12 Personality dimensions; LIHC cis rs933688 1.000 rs10474353 chr5:90732285 A/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.42 0.69 4.42e-49 Smoking behavior; LIHC cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg20607798 chr8:58055168 NA 0.49 6.23 0.32 1.34e-9 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg13395646 chr4:1353034 KIAA1530 0.41 6.44 0.33 4.1e-10 Obesity-related traits; LIHC cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg05535760 chr7:792225 HEATR2 -0.48 -6.56 -0.33 2.01e-10 Perceived unattractiveness to mosquitoes; LIHC cis rs644799 0.965 rs545342 chr11:95545369 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.07 0.68 1.05e-47 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs9457247 1.000 rs389946 chr6:167407268 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 9.91 0.47 1.64e-20 Crohn's disease; LIHC cis rs8180040 0.966 rs6792461 chr3:47473168 C/T cg27129171 chr3:47204927 SETD2 -0.57 -9.71 -0.46 7.8500000000000006e-20 Colorectal cancer; LIHC cis rs6430585 0.528 rs16832417 chr2:136744678 C/T cg25344623 chr2:136566232 LCT -0.37 -5.93 -0.31 7.26e-9 Corneal structure; LIHC cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg17971929 chr21:40555470 PSMG1 -0.48 -7.27 -0.37 2.45e-12 Cognitive function; LIHC cis rs4742903 0.875 rs10991141 chr9:106938280 T/C cg14250997 chr9:106856677 SMC2 0.35 5.94 0.31 7.03e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1419980 0.730 rs11531089 chr12:7749855 G/T cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs61990749 0.597 rs17106157 chr14:78146878 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.3 -0.49 7.3e-22 Fibroblast growth factor basic levels; LIHC cis rs5769765 0.955 rs9616367 chr22:50303515 A/C cg09182678 chr22:50328711 NA -0.43 -6.12 -0.31 2.57e-9 Schizophrenia; LIHC cis rs826838 0.967 rs1684413 chr12:39128704 G/A cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs908922 0.676 rs4845788 chr1:152519496 T/C cg20991723 chr1:152506922 NA 0.57 10.01 0.48 7.37e-21 Hair morphology; LIHC cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -6.38 -0.33 5.85e-10 Bipolar disorder and schizophrenia; LIHC cis rs34779708 0.931 rs55724039 chr10:35465397 A/G cg04310649 chr10:35416472 CREM -0.42 -5.75 -0.3 1.96e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg11170685 chr14:101005511 BEGAIN 0.38 6.08 0.31 3.21e-9 Bipolar disorder; LIHC cis rs2404602 0.692 rs12595586 chr15:77172210 A/G cg03037974 chr15:76606532 NA 0.73 14.44 0.62 3.04e-37 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01218756 chr4:48695242 FRYL 0.31 6.86 0.35 3.16e-11 Cognitive function; LIHC cis rs1983891 1.000 rs9381082 chr6:41542214 T/C cg20194872 chr6:41519635 FOXP4 0.4 6.31 0.32 8.5e-10 Prostate cancer; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg02951883 chr7:2050386 MAD1L1 0.67 11.07 0.51 1.53e-24 Bipolar disorder and schizophrenia; LIHC cis rs1670533 1.000 rs6858612 chr4:1053353 C/T cg27284194 chr4:1044797 NA 0.6 8.93 0.43 2.64e-17 Recombination rate (females); LIHC cis rs67460515 0.892 rs4856769 chr3:161004549 C/A cg03342759 chr3:160939853 NMD3 -0.66 -9.6 -0.46 1.82e-19 Parkinson's disease; LIHC cis rs7927771 0.832 rs7940536 chr11:47395240 G/A cg20135002 chr11:47629003 NA 0.5 8.4 0.41 1.17e-15 Subjective well-being; LIHC cis rs66887589 0.592 rs28580295 chr4:120278873 C/T cg09307838 chr4:120376055 NA 0.53 8.06 0.4 1.3e-14 Diastolic blood pressure; LIHC cis rs9916302 0.904 rs8076546 chr17:37555403 G/A cg07936489 chr17:37558343 FBXL20 0.84 13.52 0.59 1.18e-33 Glomerular filtration rate (creatinine); LIHC cis rs1023500 0.552 rs5758566 chr22:42454354 G/A cg00645731 chr22:42541494 CYP2D7P1 0.4 6.28 0.32 1.03e-9 Schizophrenia; LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.05 -0.31 3.87e-9 Total body bone mineral density; LIHC cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg02564969 chr6:151773285 C6orf211;RMND1 0.39 5.76 0.3 1.87e-8 Menarche (age at onset); LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg15382696 chr6:118971807 C6orf204 0.63 6.37 0.33 6.05e-10 Diastolic blood pressure; LIHC cis rs6089584 0.566 rs6061964 chr20:60607536 G/A cg23262073 chr20:60523788 NA -0.29 -6.02 -0.31 4.47e-9 Body mass index; LIHC cis rs9388451 0.839 rs4897157 chr6:126102981 A/T cg05901451 chr6:126070800 HEY2 -0.74 -16.71 -0.67 2.94e-46 Brugada syndrome; LIHC cis rs10504073 0.565 rs12056536 chr8:49890132 C/T cg00325661 chr8:49890786 NA -0.36 -8.86 -0.43 4.31e-17 Blood metabolite ratios; LIHC cis rs7539409 0.651 rs7521788 chr1:84309320 G/T cg10977910 chr1:84465055 TTLL7 0.72 7.31 0.37 1.95e-12 Alzheimer's disease; LIHC cis rs10870270 0.913 rs4550 chr10:133781798 C/T cg08754478 chr10:133766260 PPP2R2D -0.55 -8.08 -0.4 1.11e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs832187 0.813 rs704369 chr3:63868271 G/A cg16258503 chr3:63850278 ATXN7;THOC7 0.47 6.8 0.35 4.75e-11 Schizophrenia; LIHC cis rs2836950 0.502 rs2150411 chr21:40574552 G/T cg11890956 chr21:40555474 PSMG1 -0.48 -7.85 -0.39 5.32e-14 Menarche (age at onset); LIHC cis rs7584330 0.518 rs77789507 chr2:238440972 C/T cg08992911 chr2:238395768 MLPH 0.54 5.98 0.31 5.71e-9 Prostate cancer; LIHC cis rs6089584 0.507 rs28545731 chr20:60634102 C/T cg06108461 chr20:60628389 TAF4 -0.62 -8.46 -0.42 7.72e-16 Body mass index; LIHC cis rs4474465 0.688 rs7940507 chr11:78284453 T/C cg27205649 chr11:78285834 NARS2 0.51 7.94 0.39 2.9e-14 Alzheimer's disease (survival time); LIHC cis rs1552244 0.882 rs55808392 chr3:10054681 C/T cg13047869 chr3:10149882 C3orf24 0.42 5.87 0.3 1.03e-8 Alzheimer's disease; LIHC cis rs12472274 0.941 rs11677230 chr2:239092054 T/C cg17459225 chr2:239074497 NA 0.78 12.99 0.57 1.28e-31 Phospholipid levels (plasma); LIHC cis rs858239 0.539 rs57864591 chr7:23184424 T/A cg23682824 chr7:23144976 KLHL7 0.42 6.29 0.32 9.83e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs6964587 0.872 rs57969083 chr7:91665627 A/T cg17063962 chr7:91808500 NA 1.03 20.74 0.75 1.9e-62 Breast cancer; LIHC cis rs10540 1.000 rs117339389 chr11:505025 T/A cg03576123 chr11:487126 PTDSS2 -1.09 -8.17 -0.4 5.96e-15 Body mass index; LIHC cis rs644799 0.648 rs1255176 chr11:95471465 A/T cg03916912 chr11:95522834 CEP57;FAM76B 0.61 10.35 0.49 4.94e-22 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14620208 chr9:140652685 EHMT1 0.42 6.24 0.32 1.29e-9 Longevity; LIHC cis rs4845459 0.967 rs477392 chr1:152555176 C/G cg27206522 chr1:152595629 LCE3A -0.24 -5.78 -0.3 1.7e-8 Psoriasis; LIHC cis rs477692 0.905 rs508360 chr10:131424969 A/G cg05714579 chr10:131428358 MGMT 0.5 8.55 0.42 4.06e-16 Response to temozolomide; LIHC cis rs644799 0.965 rs499076 chr11:95546341 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.52e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs877282 0.891 rs12767062 chr10:797961 C/T cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs7927592 0.956 rs948315 chr11:68309140 T/C cg16797656 chr11:68205561 LRP5 0.52 8.21 0.41 4.53e-15 Total body bone mineral density; LIHC cis rs8078723 0.677 rs8073254 chr17:38149350 C/G cg17344932 chr17:38183730 MED24;SNORD124 0.66 11.37 0.52 1.21e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs8108269 1.000 rs8108269 chr19:46158513 G/T cg13320842 chr19:46175254 GIPR -0.41 -7.79 -0.39 7.91e-14 Type 2 diabetes; LIHC cis rs7100689 0.577 rs9421464 chr10:82043426 C/T cg01528321 chr10:82214614 TSPAN14 0.85 11.77 0.54 4.57e-27 Post bronchodilator FEV1; LIHC cis rs4713118 0.666 rs2893930 chr6:27738806 T/C cg20933634 chr6:27740509 NA 0.48 6.26 0.32 1.15e-9 Parkinson's disease; LIHC cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg18252515 chr7:66147081 NA 1.29 17.4 0.69 4.95e-49 Diabetic kidney disease; LIHC cis rs7116495 1.000 rs548961 chr11:71793887 G/A cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs11997175 0.766 rs6995220 chr8:33708919 C/A cg04338863 chr8:33670619 NA 0.31 5.8 0.3 1.49e-8 Body mass index; LIHC cis rs6547741 0.904 rs2384659 chr2:27856793 G/A cg27432699 chr2:27873401 GPN1 0.75 12.49 0.56 9.64e-30 Oral cavity cancer; LIHC cis rs853679 0.517 rs9380055 chr6:28081629 A/G cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs10845606 0.505 rs2160972 chr12:12838608 C/T cg04607235 chr12:12878440 APOLD1 0.46 6.7 0.34 8.41e-11 Systemic lupus erythematosus; LIHC cis rs9303401 1.000 rs6503882 chr17:56915761 T/C cg12560992 chr17:57184187 TRIM37 0.73 10.71 0.5 2.93e-23 Cognitive test performance; LIHC cis rs7487075 0.619 rs67249026 chr12:46835768 T/C cg23829395 chr12:46796953 NA 0.35 6.19 0.32 1.76e-9 Itch intensity from mosquito bite; LIHC cis rs8067354 0.574 rs1295923 chr17:57960436 A/G cg02344993 chr17:57696989 CLTC 0.66 10.3 0.49 7.37e-22 Hemoglobin concentration; LIHC cis rs7208859 0.673 rs2269916 chr17:29233763 A/G cg14067834 chr17:29058358 SUZ12P 0.67 6.54 0.33 2.2e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg18230493 chr5:56204884 C5orf35 -0.47 -6.45 -0.33 3.78e-10 Initial pursuit acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06713199 chr3:28390809 AZI2 0.36 6.13 0.31 2.41e-9 Cognitive function; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05262634 chr1:38157968 CDCA8 -0.54 -6.12 -0.31 2.6e-9 Systolic blood pressure; LIHC cis rs4908760 0.899 rs61783642 chr1:8591397 T/C cg20416874 chr1:8611966 RERE -0.67 -14.25 -0.61 1.67e-36 Vitiligo; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.55 0.56 5.59e-30 Prudent dietary pattern; LIHC cis rs9628987 0.569 rs2289732 chr1:8423877 G/C cg20416874 chr1:8611966 RERE 0.53 6.36 0.33 6.49e-10 Breast cancer; LIHC cis rs4975709 0.589 rs4975746 chr5:1861069 G/A cg15595755 chr5:1867978 NA 0.4 8.04 0.4 1.48e-14 Cardiovascular disease risk factors; LIHC cis rs5758511 0.680 rs5758657 chr22:42618669 A/G cg00645731 chr22:42541494 CYP2D7P1 0.53 8.55 0.42 4.23e-16 Birth weight; LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.12 0.31 2.57e-9 Renal cell carcinoma; LIHC cis rs61008539 0.586 rs6959154 chr7:856320 C/T cg00475322 chr7:917719 C7orf20 0.39 6.42 0.33 4.68e-10 Perceived unattractiveness to mosquitoes; LIHC cis rs7635838 0.617 rs346076 chr3:11292682 A/G cg00170343 chr3:11313890 ATG7 -0.59 -9.91 -0.47 1.66e-20 HDL cholesterol; LIHC cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg18404041 chr3:52824283 ITIH1 -0.53 -8.31 -0.41 2.3e-15 Bipolar disorder; LIHC cis rs2073499 1.000 rs79499880 chr3:50259551 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.67 6.82 0.35 4.03e-11 Schizophrenia; LIHC cis rs73001065 0.818 rs12610191 chr19:19721976 C/T cg03709012 chr19:19516395 GATAD2A 0.85 7.8 0.39 7.47e-14 LDL cholesterol; LIHC cis rs6665290 0.904 rs3795449 chr1:227181838 T/G cg10327440 chr1:227177885 CDC42BPA -1.18 -26.78 -0.82 6.04e-86 Myeloid white cell count; LIHC cis rs4975616 0.710 rs27996 chr5:1345474 A/G cg06550200 chr5:1325588 CLPTM1L -0.62 -9.62 -0.46 1.52e-19 Lung cancer; LIHC cis rs1707322 1.000 rs6661500 chr1:46465662 T/C cg03146154 chr1:46216737 IPP 0.47 7.67 0.38 1.79e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs796364 1.000 rs281783 chr2:200751582 G/A cg23649088 chr2:200775458 C2orf69 0.49 5.82 0.3 1.36e-8 Schizophrenia; LIHC cis rs1949733 0.523 rs16842563 chr4:8545146 C/T cg11789530 chr4:8429930 ACOX3 -0.57 -7.86 -0.39 5.04e-14 Response to antineoplastic agents; LIHC cis rs11650776 1 rs11650776 chr17:37641402 G/A cg00129232 chr17:37814104 STARD3 -0.43 -6.89 -0.35 2.68e-11 Lung function (FEV1); LIHC cis rs8044995 0.563 rs56899435 chr16:68395675 G/A cg03983715 chr16:68378420 PRMT7 -0.52 -6.2 -0.32 1.67e-9 Schizophrenia; LIHC cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg05890377 chr2:74357713 NA 0.63 12.47 0.56 1.12e-29 Gestational age at birth (maternal effect); LIHC cis rs4803468 1.000 rs11670668 chr19:41920454 G/C cg09537434 chr19:41945824 ATP5SL -1.02 -21.69 -0.76 3.18e-66 Height; LIHC cis rs10751667 0.643 rs10902245 chr11:953014 C/T ch.11.42038R chr11:967971 AP2A2 -0.54 -9.61 -0.46 1.62e-19 Alzheimer's disease (late onset); LIHC cis rs910316 0.789 rs175444 chr14:75601782 G/C cg08847533 chr14:75593920 NEK9 -0.87 -17.89 -0.7 5.5e-51 Height; LIHC cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.27e-12 Bipolar disorder; LIHC cis rs6952808 0.825 rs34922657 chr7:1938655 C/T cg04267008 chr7:1944627 MAD1L1 -0.7 -10.91 -0.51 5.71e-24 Bipolar disorder and schizophrenia; LIHC cis rs933688 1.000 rs10073935 chr5:90742188 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.86 18.23 0.7 2.43e-52 Smoking behavior; LIHC cis rs12477438 0.539 rs62156558 chr2:99553104 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.72 -10.08 -0.48 4.3e-21 Chronic sinus infection; LIHC cis rs7552404 0.855 rs385897 chr1:76106962 T/C cg10523679 chr1:76189770 ACADM -0.66 -9.21 -0.45 3.36e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7408868 0.908 rs62113794 chr19:15277337 C/A cg02272795 chr19:15279244 NOTCH3 -0.31 -5.75 -0.3 2.02e-8 Pulse pressure; LIHC cis rs9649465 0.967 rs10224062 chr7:123304609 G/A cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.56e-14 Migraine; LIHC cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg24531977 chr5:56204891 C5orf35 -0.74 -10.31 -0.49 6.85e-22 Initial pursuit acceleration; LIHC cis rs9640161 0.702 rs11765692 chr7:150026567 C/T cg17279839 chr7:150038598 RARRES2 0.51 10.6 0.5 6.69e-23 Blood protein levels;Circulating chemerin levels; LIHC trans rs11098499 0.909 rs11723839 chr4:120299673 G/A cg25214090 chr10:38739885 LOC399744 0.56 8.84 0.43 5.07e-17 Corneal astigmatism; LIHC cis rs6163 0.588 rs12763284 chr10:104508202 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.47 6.86 0.35 3.25e-11 Waist circumference;Hip circumference; LIHC cis rs2231884 0.697 rs11227332 chr11:65623739 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.53 5.82 0.3 1.36e-8 Inflammatory bowel disease; LIHC cis rs506338 0.517 rs471618 chr11:64465403 T/C cg08800856 chr11:64428347 NRXN2 0.39 6.04 0.31 4.13e-9 Body mass index;Urate levels; LIHC cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs36051895 0.664 rs3780370 chr9:5095167 A/C cg02405213 chr9:5042618 JAK2 -0.66 -10.97 -0.51 3.34e-24 Pediatric autoimmune diseases; LIHC cis rs11030122 0.661 rs10767811 chr11:4066398 G/A cg18678763 chr11:4115507 RRM1 -0.58 -8.78 -0.43 8.02e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs679087 0.833 rs302343 chr12:29940206 T/G cg14258853 chr12:29935411 TMTC1 -0.45 -6.84 -0.35 3.58e-11 Schizophrenia; LIHC cis rs12594515 1.000 rs7162201 chr15:45992658 A/C cg01629716 chr15:45996671 NA 0.51 9.16 0.44 4.72e-18 Waist circumference;Weight; LIHC cis rs7927592 0.956 rs11228269 chr11:68289796 A/G cg16797656 chr11:68205561 LRP5 0.52 8.29 0.41 2.66e-15 Total body bone mineral density; LIHC cis rs1866706 0.896 rs4757062 chr11:12876491 C/T cg25843174 chr11:12811716 TEAD1 -0.28 -6.01 -0.31 4.78e-9 Intelligence (multi-trait analysis); LIHC cis rs7940866 0.838 rs10736592 chr11:130800572 C/T cg12179176 chr11:130786555 SNX19 0.67 10.13 0.48 2.79e-21 Schizophrenia; LIHC cis rs8017423 0.935 rs3742668 chr14:90767759 G/A cg14092571 chr14:90743983 NA 0.42 6.52 0.33 2.57e-10 Mortality in heart failure; LIHC cis rs2239547 0.618 rs13083728 chr3:52868445 G/A cg11645453 chr3:52864694 ITIH4 0.34 8.84 0.43 5.03e-17 Schizophrenia; LIHC cis rs716804 0.740 rs7107290 chr11:10294772 G/A cg01453529 chr11:10209919 SBF2 -0.29 -5.89 -0.3 9.09e-9 Neuroticism; LIHC cis rs6754311 0.731 rs892715 chr2:136576577 T/C cg17750252 chr2:136567154 LCT 0.35 6.32 0.32 8.34e-10 Mosquito bite size; LIHC cis rs9640161 0.659 rs77354576 chr7:150013300 A/C cg21361702 chr7:150065534 REPIN1 0.47 6.57 0.33 1.9e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs2228479 0.717 rs11644967 chr16:89806614 T/A cg04013166 chr16:89971882 TCF25 0.48 6.11 0.31 2.75e-9 Skin colour saturation; LIHC cis rs11785400 1.000 rs4557682 chr8:143738182 T/C cg10596483 chr8:143751796 JRK 0.52 8.46 0.42 7.64e-16 Schizophrenia; LIHC cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg03452623 chr4:187889614 NA 0.32 8.34 0.41 1.89e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7607369 0.714 rs2272190 chr2:219609995 G/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.97e-10 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7223966 1.000 rs9912201 chr17:61763208 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.59 0.34 1.64e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs651907 0.557 rs36002990 chr3:101437862 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.4 0.52 9.54e-26 Colorectal cancer; LIHC cis rs16958440 0.708 rs1434528 chr18:44632323 G/A cg17192377 chr18:44677553 HDHD2 0.52 6.53 0.33 2.38e-10 Sitting height ratio; LIHC cis rs9549367 0.789 rs12869947 chr13:113896156 A/G cg18105134 chr13:113819100 PROZ -0.67 -11.58 -0.53 2.23e-26 Platelet distribution width; LIHC cis rs6701037 0.748 rs2685 chr1:175127771 A/G cg00958927 chr1:175162553 KIAA0040 0.39 6.67 0.34 1.01e-10 Alcohol dependence; LIHC cis rs864643 0.891 rs1068953 chr3:39556561 A/G cg05136238 chr3:39556330 MOBP 0.32 5.81 0.3 1.47e-8 Attention deficit hyperactivity disorder; LIHC cis rs611744 0.836 rs684412 chr8:109210905 T/A cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs2153535 0.580 rs1335628 chr6:8491742 A/T cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC trans rs7618501 0.722 rs9853458 chr3:49783211 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.898 rs72798064 chr2:23982832 T/C cg08917208 chr2:24149416 ATAD2B 0.83 7.54 0.38 4.22e-13 Lymphocyte counts; LIHC trans rs6489882 0.867 rs6489875 chr12:113368030 G/A cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs763121 0.853 rs5750633 chr22:38993467 A/G cg06022373 chr22:39101656 GTPBP1 0.75 15.08 0.63 9.62e-40 Menopause (age at onset); LIHC cis rs2070488 0.965 rs6796845 chr3:38567771 C/A cg24069376 chr3:38537580 EXOG -0.38 -6.84 -0.35 3.64e-11 Electrocardiographic conduction measures; LIHC trans rs916888 0.697 rs199516 chr17:44856485 C/T cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1707322 0.927 rs11211194 chr1:46282084 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.19 0.32 1.71e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7246657 0.943 rs10404920 chr19:37881556 T/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.87 8.18 0.4 5.67e-15 Platelet count; LIHC cis rs3617 0.572 rs2245538 chr3:52852060 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.86 0.3 1.08e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs17106184 1.000 rs12063943 chr1:51223263 T/C cg07174182 chr1:51127561 FAF1 -0.63 -6.86 -0.35 3.32e-11 Type 2 diabetes; LIHC cis rs9896933 0.887 rs78483419 chr17:80870884 T/C cg02398342 chr17:80708632 TBCD;FN3K 0.6 5.76 0.3 1.84e-8 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs8067354 0.574 rs1292035 chr17:57989557 G/A cg13753209 chr17:57696993 CLTC 0.71 10.57 0.5 8.45e-23 Hemoglobin concentration; LIHC cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.53 -7.48 -0.37 6.53e-13 Electroencephalogram traits; LIHC cis rs921968 0.608 rs658378 chr2:219483881 T/A cg18887096 chr2:219472410 PLCD4 0.36 6.18 0.32 1.87e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs12762955 0.529 rs2387213 chr10:1051420 C/T cg26597838 chr10:835615 NA 0.46 5.74 0.3 2.14e-8 Response to angiotensin II receptor blocker therapy; LIHC cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg22442454 chr1:209979470 IRF6 0.4 6.07 0.31 3.43e-9 Cleft lip with or without cleft palate; LIHC cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg22508957 chr16:3507546 NAT15 -0.47 -8.31 -0.41 2.33e-15 Tuberculosis; LIHC cis rs7534824 0.543 rs61780298 chr1:101402982 T/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.57 0.38 3.53e-13 Refractive astigmatism; LIHC cis rs7086627 0.515 rs7088877 chr10:82208860 C/G cg00277334 chr10:82204260 NA -0.85 -14.2 -0.61 2.64e-36 Post bronchodilator FEV1; LIHC trans rs1005277 0.579 rs176886 chr10:38403974 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs7617773 0.780 rs79089926 chr3:48348564 A/C cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs6088813 0.857 rs1886692 chr20:33986549 C/T cg14752227 chr20:34000481 UQCC -0.41 -5.96 -0.31 6.25e-9 Height; LIHC cis rs7615952 0.641 rs61048217 chr3:125807905 G/T cg05084668 chr3:125655381 ALG1L -0.39 -5.99 -0.31 5.24e-9 Blood pressure (smoking interaction); LIHC cis rs651907 0.557 rs3806654 chr3:101396529 G/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.47 -6.72 -0.34 7.5e-11 Colorectal cancer; LIHC cis rs9911578 0.900 rs8067264 chr17:57182793 G/C cg05425664 chr17:57184151 TRIM37 -0.6 -9.0 -0.44 1.61e-17 Intelligence (multi-trait analysis); LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg18954051 chr12:66554863 TMBIM4 0.39 6.2 0.32 1.65e-9 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC trans rs2739330 0.828 rs5760107 chr22:24252597 T/C cg06437703 chr8:37914619 EIF4EBP1 -0.52 -7.93 -0.39 3.13e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.59 9.06 0.44 1.06e-17 Height; LIHC cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg18225595 chr11:63971243 STIP1 0.66 8.26 0.41 3.31e-15 Mean platelet volume; LIHC cis rs372883 0.613 rs1153274 chr21:30660026 T/C cg24692254 chr21:30365293 RNF160 -0.52 -6.49 -0.33 3.08e-10 Pancreatic cancer; LIHC cis rs9473924 0.542 rs9473939 chr6:50877477 T/G cg14470998 chr6:50812995 TFAP2B 0.91 10.53 0.49 1.22e-22 Body mass index; LIHC trans rs9929218 0.551 rs3785134 chr16:68728938 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.89 20.56 0.74 1.01e-61 Colorectal cancer; LIHC cis rs477895 0.713 rs11607165 chr11:63963947 T/G cg04317338 chr11:64019027 PLCB3 0.84 10.13 0.48 2.89e-21 Mean platelet volume; LIHC cis rs757110 0.770 rs1557765 chr11:17403639 T/C cg15432903 chr11:17409602 KCNJ11 0.65 10.18 0.48 1.94e-21 Type 2 diabetes; LIHC cis rs11053548 0.678 rs11053550 chr12:10172353 T/C cg04314261 chr12:10163030 CLEC12B 0.42 6.3 0.32 9.31e-10 Systolic blood pressure in sickle cell anemia; LIHC cis rs288342 0.832 rs288240 chr2:183644191 T/C cg02625481 chr2:183667124 NA -0.29 -5.93 -0.31 7.36e-9 Recurrent major depressive disorder; LIHC cis rs472402 0.580 rs3822430 chr5:6651970 A/G cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.46 -5.78 -0.3 1.71e-8 Response to amphetamines; LIHC cis rs17401966 0.800 rs2039778 chr1:10354601 A/G cg15208524 chr1:10270712 KIF1B 0.38 5.72 0.3 2.29e-8 Hepatocellular carcinoma; LIHC cis rs11627756 0.957 rs11846451 chr14:103131723 T/C cg12046867 chr14:103022105 NA 0.39 5.93 0.31 7.27e-9 Mean platelet volume; LIHC cis rs2625529 0.824 rs2306488 chr15:72292115 A/G cg16672083 chr15:72433130 SENP8 -0.31 -5.81 -0.3 1.47e-8 Red blood cell count; LIHC cis rs5769765 0.955 rs8135816 chr22:50291976 G/C cg26441486 chr22:50317300 CRELD2 0.36 6.38 0.33 5.73e-10 Schizophrenia; LIHC cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg02931644 chr1:25747376 RHCE 0.35 7.74 0.39 1.17e-13 Erythrocyte sedimentation rate; LIHC cis rs35110281 0.774 rs141521 chr21:44963686 G/A cg04455712 chr21:45112962 RRP1B 0.44 7.46 0.37 7.29e-13 Mean corpuscular volume; LIHC cis rs11122272 0.701 rs2486725 chr1:231540288 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.77e-22 Hemoglobin concentration; LIHC cis rs10504229 0.861 rs60346509 chr8:58196050 G/T cg20607798 chr8:58055168 NA 0.59 6.85 0.35 3.44e-11 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.704 rs798512 chr7:2782592 C/G cg19717773 chr7:2847554 GNA12 -0.4 -7.04 -0.36 1.06e-11 Height; LIHC cis rs6442522 0.640 rs3773447 chr3:15520019 G/T cg16303742 chr3:15540471 COLQ 0.39 6.36 0.33 6.44e-10 Uric acid levels; LIHC cis rs367615 0.506 rs2963021 chr5:108800365 C/T cg17395555 chr5:108820864 NA 0.33 6.92 0.35 2.24e-11 Colorectal cancer (SNP x SNP interaction); LIHC cis rs4773330 0.925 rs1891962 chr13:111809528 C/T cg26911804 chr13:111806221 ARHGEF7 0.62 6.09 0.31 3.04e-9 Bilirubin levels; LIHC cis rs11690935 0.851 rs7581072 chr2:172859849 C/T cg13550731 chr2:172543902 DYNC1I2 -0.83 -14.54 -0.62 1.3e-37 Schizophrenia; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg13012494 chr21:47604986 C21orf56 -0.38 -5.83 -0.3 1.31e-8 Testicular germ cell tumor; LIHC cis rs7312933 0.558 rs1796384 chr12:42780568 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.54 -8.18 -0.4 5.8e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs1997066 0.920 rs7088485 chr10:106725993 T/C cg21239439 chr6:170038665 WDR27 0.67 6.08 0.31 3.23e-9 Diabetic kidney disease; LIHC trans rs7395662 0.591 rs7482521 chr11:48609735 G/A cg03929089 chr4:120376271 NA -0.4 -6.09 -0.31 3.02e-9 HDL cholesterol; LIHC cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.83 0.3 1.29e-8 Schizophrenia; LIHC cis rs7312933 0.703 rs10880259 chr12:42558003 T/C cg17420585 chr12:42539391 GXYLT1 -0.37 -5.96 -0.31 6.39e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs12995491 0.933 rs7590305 chr2:88513131 C/T cg04511125 chr2:88470314 THNSL2 -0.4 -5.72 -0.3 2.35e-8 Response to metformin (IC50); LIHC cis rs703842 1.000 rs10783847 chr12:58196447 G/A cg18357645 chr12:58087776 OS9 -0.44 -7.03 -0.36 1.12e-11 Multiple sclerosis; LIHC cis rs6733011 0.578 rs12468024 chr2:99495980 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.44 -6.37 -0.33 6.16e-10 Bipolar disorder; LIHC cis rs7793919 0.726 rs10261971 chr7:4776547 A/G cg09789173 chr7:4769017 FOXK1 0.72 10.73 0.5 2.34e-23 Mosquito bite size; LIHC cis rs10416265 0.528 rs17884930 chr19:33595390 A/G cg17764715 chr19:33622953 WDR88 0.48 6.37 0.33 6.05e-10 Bone properties (heel); LIHC cis rs8077889 0.750 rs231533 chr17:41945588 A/G cg26893861 chr17:41843967 DUSP3 -0.77 -7.17 -0.36 4.76e-12 Triglycerides; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07638904 chr22:19166425 SLC25A1 -0.47 -6.17 -0.32 1.95e-9 Systolic blood pressure; LIHC cis rs798554 0.679 rs1636250 chr7:2884433 T/C cg13628971 chr7:2884303 GNA12 0.6 10.08 0.48 4.24e-21 Height; LIHC cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg13866156 chr1:1669148 SLC35E2 -0.68 -13.09 -0.58 5.25e-32 Body mass index; LIHC cis rs7618501 0.633 rs2526751 chr3:50064867 T/C cg21467203 chr3:49911342 NA 0.43 7.61 0.38 2.66e-13 Intelligence (multi-trait analysis); LIHC cis rs875971 0.862 rs6460306 chr7:66060793 T/C cg18876405 chr7:65276391 NA -0.34 -6.3 -0.32 9.23e-10 Aortic root size; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg06873352 chr17:61820015 STRADA 0.72 12.72 0.57 1.29e-30 Prudent dietary pattern; LIHC cis rs3814244 0.528 rs61923060 chr12:68391121 T/C cg15249341 chr12:68405565 NA -0.32 -6.28 -0.32 1.03e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg14559409 chr10:65930703 NA 0.36 6.35 0.32 6.69e-10 Immature fraction of reticulocytes; LIHC cis rs7666738 1.000 rs1426673 chr4:98924024 G/A cg05340658 chr4:99064831 C4orf37 0.67 11.56 0.53 2.57e-26 Colonoscopy-negative controls vs population controls; LIHC trans rs783540 0.542 rs62009945 chr15:83299956 T/A cg18393722 chr15:85113863 UBE2QP1 -0.46 -6.96 -0.35 1.78e-11 Schizophrenia; LIHC cis rs11673344 0.704 rs826262 chr19:37419442 G/A cg27390819 chr19:37464633 NA -0.48 -5.83 -0.3 1.3e-8 Obesity-related traits; LIHC cis rs7582180 0.629 rs2164847 chr2:100958715 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.58 0.42 3.3e-16 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.675 rs1684258 chr11:49340020 G/A cg18944383 chr4:111397179 ENPEP -0.31 -6.77 -0.34 5.74e-11 Coronary artery disease; LIHC cis rs6684514 1.000 rs3806409 chr1:156252291 A/G cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs34172651 0.517 rs189919 chr16:24737741 G/A cg04756594 chr16:24857601 SLC5A11 -0.55 -7.98 -0.4 2.18e-14 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs4974484 chr3:134219019 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 -0.39 -5.76 -0.3 1.88e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg16145915 chr7:1198662 ZFAND2A -0.4 -10.74 -0.5 2.14e-23 Longevity;Endometriosis; LIHC cis rs7772486 0.603 rs2223411 chr6:146028767 T/C cg05347473 chr6:146136440 FBXO30 -0.45 -6.98 -0.35 1.5e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg12310025 chr6:25882481 NA -0.69 -8.53 -0.42 4.71e-16 Intelligence (multi-trait analysis); LIHC cis rs17776563 0.887 rs28790085 chr15:89128287 T/C cg05013243 chr15:89149849 MIR1179 0.4 6.69 0.34 9.16e-11 Thyroid hormone levels; LIHC cis rs950776 0.684 rs11637635 chr15:78877150 A/G cg06917634 chr15:78832804 PSMA4 -0.68 -9.16 -0.44 4.92e-18 Sudden cardiac arrest; LIHC cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC trans rs526821 0.595 rs624478 chr11:55340778 C/G cg15704280 chr7:45808275 SEPT13 -0.51 -7.76 -0.39 9.91e-14 Pediatric bone mineral density (spine); LIHC cis rs5758511 0.680 rs5758682 chr22:42645202 C/T cg00645731 chr22:42541494 CYP2D7P1 0.53 8.59 0.42 3.1e-16 Birth weight; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06044117 chr11:95523445 FAM76B;CEP57 0.5 6.6 0.34 1.55e-10 Lung function (FEV1/FVC); LIHC cis rs2479724 0.625 rs9394835 chr6:41818200 A/T cg17623882 chr6:41773611 USP49 -0.39 -5.79 -0.3 1.57e-8 Menarche (age at onset); LIHC cis rs35110281 0.776 rs229357 chr21:44982717 T/C cg21573476 chr21:45109991 RRP1B -0.58 -11.08 -0.51 1.36e-24 Mean corpuscular volume; LIHC cis rs2463822 1.000 rs2463822 chr11:62103420 T/C cg06239285 chr11:62104954 ASRGL1 0.97 7.08 0.36 8.01e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2576037 0.526 rs4890703 chr18:44522037 A/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.46 -0.33 3.61e-10 Personality dimensions; LIHC cis rs651907 0.535 rs11712309 chr3:101519097 T/C cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs273218 0.573 rs11742692 chr5:53343576 C/T ch.5.1024479R chr5:53302184 ARL15 -0.87 -15.2 -0.63 3.13e-40 Migraine; LIHC cis rs5769765 0.505 rs4561759 chr22:50256686 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.58 5.81 0.3 1.44e-8 Schizophrenia; LIHC cis rs12586317 0.548 rs12590678 chr14:35602956 C/T cg16230307 chr14:35515116 FAM177A1 0.76 12.68 0.57 1.9e-30 Psoriasis; LIHC cis rs12079745 0.793 rs114133365 chr1:169270540 G/C cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 1.96e-11 QT interval; LIHC cis rs1904096 0.506 rs2632412 chr4:95149319 A/C cg11021082 chr4:95130006 SMARCAD1 0.46 8.06 0.4 1.33e-14 Type 2 diabetes; LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.92 -0.3 7.75e-9 Menopause (age at onset); LIHC cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg06138931 chr13:21896616 NA 0.51 8.7 0.43 1.42e-16 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27539627 chr3:122513065 DIRC2;HSPBAP1 0.45 7.19 0.36 4e-12 Cognitive function; LIHC cis rs8114671 0.836 rs6058154 chr20:33585834 C/T cg07148914 chr20:33460835 GGT7 -0.57 -8.53 -0.42 4.82e-16 Height; LIHC trans rs72960926 0.744 rs55962148 chr6:74962021 G/T cg07247405 chr1:2484626 LOC115110 0.53 6.38 0.33 5.78e-10 Metabolite levels (MHPG); LIHC cis rs1018836 0.892 rs1476428 chr8:91555603 G/T cg16814680 chr8:91681699 NA -0.49 -7.69 -0.38 1.59e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs12125971 1.000 rs12026381 chr1:107459241 C/T cg08941669 chr1:7778234 CAMTA1 0.57 6.09 0.31 3e-9 Intelligence; LIHC cis rs17125944 0.615 rs11629431 chr14:53320528 C/G cg00686598 chr14:53173677 PSMC6 -0.76 -8.71 -0.43 1.36e-16 Alzheimer's disease (late onset); LIHC cis rs10504073 0.669 rs818559 chr8:50035806 C/T cg00325661 chr8:49890786 NA 0.32 7.26 0.37 2.64e-12 Blood metabolite ratios; LIHC cis rs2197308 0.765 rs2387436 chr12:37935337 C/T cg26384229 chr12:38710491 ALG10B -0.48 -6.7 -0.34 8.5e-11 Morning vs. evening chronotype; LIHC cis rs244731 0.959 rs7724098 chr5:176659570 G/A cg17509989 chr5:176798049 RGS14 -0.68 -6.38 -0.33 5.82e-10 Urate levels in lean individuals; LIHC cis rs1401999 1.000 rs6804242 chr3:183659463 A/T cg01324343 chr3:183735012 ABCC5 0.75 12.36 0.56 2.92e-29 Anterior chamber depth; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg04998419 chr1:40626967 RLF -0.42 -6.14 -0.32 2.24e-9 Eotaxin levels; LIHC cis rs7520050 0.966 rs6695809 chr1:46285461 T/C cg03146154 chr1:46216737 IPP -0.4 -6.54 -0.33 2.24e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7589728 0.844 rs2363010 chr2:88496399 G/C cg04511125 chr2:88470314 THNSL2 0.9 8.67 0.42 1.7e-16 Plasma clusterin levels; LIHC cis rs61990749 0.544 rs11628888 chr14:78161506 T/C cg21497246 chr14:78225524 SNW1;C14orf178 0.5 7.68 0.38 1.68e-13 Fibroblast growth factor basic levels; LIHC cis rs2710642 0.777 rs2539987 chr2:63142864 A/G cg17519650 chr2:63277830 OTX1 0.56 8.49 0.42 6.22e-16 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1997103 1.000 rs4948011 chr7:55403859 A/G cg17469321 chr7:55412551 NA 0.46 6.81 0.35 4.38e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1800682 0.528 rs11202918 chr10:90742008 A/G cg03111039 chr10:90751583 FAS;ACTA2 0.73 11.88 0.54 1.69e-27 Chronic lymphocytic leukemia; LIHC trans rs2727020 0.554 rs7111711 chr11:49557880 G/A cg03929089 chr4:120376271 NA -0.7 -10.22 -0.48 1.44e-21 Coronary artery disease; LIHC trans rs12807809 0.588 rs61910607 chr11:124609369 T/G cg14028684 chr12:48723360 H1FNT 0.42 6.43 0.33 4.4e-10 Schizophrenia; LIHC cis rs311392 0.902 rs419813 chr8:55092385 A/T cg11783602 chr8:55087084 NA -0.31 -6.2 -0.32 1.66e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg16822855 chr3:40428330 ENTPD3 0.33 5.96 0.31 6.36e-9 Renal cell carcinoma; LIHC cis rs1862618 0.641 rs2591954 chr5:56245044 G/C cg24531977 chr5:56204891 C5orf35 0.52 7.47 0.37 6.66e-13 Initial pursuit acceleration; LIHC cis rs1348850 0.914 rs2121430 chr2:178318375 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.74 11.07 0.51 1.54e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg06558623 chr16:89946397 TCF25 0.86 13.43 0.59 2.5e-33 Skin colour saturation; LIHC cis rs11122272 0.735 rs2486728 chr1:231535883 T/G cg06096015 chr1:231504339 EGLN1 0.49 9.19 0.44 3.94e-18 Hemoglobin concentration; LIHC cis rs11758351 0.660 rs55643278 chr6:26222888 C/A cg16070018 chr6:26224392 HIST1H3E 0.61 7.33 0.37 1.67e-12 Gout;Renal underexcretion gout; LIHC cis rs3820068 0.655 rs11587521 chr1:15839206 T/C cg17385448 chr1:15911702 AGMAT 0.38 6.48 0.33 3.23e-10 Systolic blood pressure; LIHC cis rs919433 0.927 rs3843857 chr2:198195965 T/C cg10820045 chr2:198174542 NA -0.56 -9.22 -0.45 3.01e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs1005277 0.579 rs2474586 chr10:38418882 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.25 0.32 1.24e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4474465 0.920 rs10899526 chr11:78206157 T/C cg27205649 chr11:78285834 NARS2 0.41 6.31 0.32 8.48e-10 Alzheimer's disease (survival time); LIHC cis rs763121 0.853 rs1569716 chr22:38998519 C/A cg14440974 chr22:39074834 NA -0.36 -5.97 -0.31 5.9e-9 Menopause (age at onset); LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg24209194 chr3:40518798 ZNF619 0.63 9.7 0.46 8.18e-20 Renal cell carcinoma; LIHC cis rs798554 0.679 rs2533870 chr7:2885274 C/G cg04166393 chr7:2884313 GNA12 -0.49 -8.03 -0.4 1.56e-14 Height; LIHC trans rs11039798 0.502 rs961863 chr11:48417021 T/C cg15704280 chr7:45808275 SEPT13 -0.57 -6.32 -0.32 8.05e-10 Axial length; LIHC cis rs926392 0.932 rs6124105 chr20:37686081 G/A cg16355469 chr20:37678765 NA 0.38 5.98 0.31 5.76e-9 Dialysis-related mortality; LIHC cis rs17106184 1.000 rs59390962 chr1:51314531 C/T cg07174182 chr1:51127561 FAF1 -0.62 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11885407 chr3:193310886 OPA1 -0.5 -6.93 -0.35 2.06e-11 Pancreatic cancer; LIHC cis rs6750047 0.628 rs2855655 chr2:38304488 T/C cg07380506 chr2:38303506 CYP1B1 0.58 6.8 0.35 4.55e-11 Cutaneous malignant melanoma;Melanoma; LIHC cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.75e-9 Menopause (age at onset); LIHC cis rs933688 1.000 rs1035477 chr5:90743325 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.39 0.66 5.8e-45 Smoking behavior; LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg04498913 chr7:1135747 C7orf50 0.44 6.94 0.35 1.98e-11 Bronchopulmonary dysplasia; LIHC cis rs999943 0.846 rs10947422 chr6:33611351 G/A cg14003231 chr6:33640908 ITPR3 0.35 7.47 0.37 6.54e-13 Obesity (extreme); LIHC cis rs8038465 0.592 rs58443257 chr15:73930707 A/T cg15420318 chr15:73925796 NPTN 0.47 7.16 0.36 5.07e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9303280 0.901 rs12950743 chr17:38049233 T/C cg11212589 chr17:38028394 ZPBP2 0.37 7.74 0.39 1.16e-13 Self-reported allergy; LIHC cis rs36051895 0.623 rs7023639 chr9:5244058 A/C cg02405213 chr9:5042618 JAK2 -0.66 -11.16 -0.52 7.05e-25 Pediatric autoimmune diseases; LIHC cis rs2637266 0.628 rs846632 chr10:78535759 C/A cg18941641 chr10:78392320 NA 0.28 5.96 0.31 6.12e-9 Pulmonary function; LIHC cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg13393036 chr8:95962371 TP53INP1 -0.42 -9.99 -0.48 8.51e-21 Type 2 diabetes; LIHC cis rs9790314 0.521 rs2122527 chr3:161091636 G/A cg17135325 chr3:160939158 NMD3 0.42 6.1 0.31 2.84e-9 Morning vs. evening chronotype; LIHC cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2304069 0.545 rs9686746 chr5:149399968 G/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.59 8.18 0.4 5.52e-15 HIV-1 control; LIHC cis rs10876993 0.928 rs10877001 chr12:58083077 T/C cg15848620 chr12:58087721 OS9 0.57 7.84 0.39 5.67e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs10504229 0.593 rs80174614 chr8:58024631 G/A cg20607798 chr8:58055168 NA 0.49 6.94 0.35 2.02e-11 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.850 rs11640209 chr16:89807828 C/A cg04013166 chr16:89971882 TCF25 0.49 6.07 0.31 3.31e-9 Skin colour saturation; LIHC trans rs1005277 0.579 rs1985707 chr10:38434098 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg07061783 chr6:25882402 NA 0.65 8.39 0.41 1.32e-15 Blood metabolite levels; LIHC cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg01570182 chr17:44337453 NA 1.0 9.9 0.47 1.8e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2710642 0.611 rs2204656 chr2:62883868 C/T cg17519650 chr2:63277830 OTX1 -0.44 -6.21 -0.32 1.53e-9 LDL cholesterol levels;LDL cholesterol; LIHC cis rs3806843 0.676 rs2563304 chr5:140072057 C/T cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg01238044 chr22:24384105 GSTT1 -0.42 -5.85 -0.3 1.13e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg19635926 chr16:89946313 TCF25 0.52 7.02 0.36 1.17e-11 Skin colour saturation; LIHC cis rs896854 0.517 rs896851 chr8:95950251 T/C cg16049864 chr8:95962084 TP53INP1 -0.46 -7.33 -0.37 1.73e-12 Type 2 diabetes; LIHC cis rs9325144 0.624 rs10783329 chr12:39113951 C/T cg26384229 chr12:38710491 ALG10B -0.42 -6.0 -0.31 5.06e-9 Morning vs. evening chronotype; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.69 0.38 1.6e-13 Prudent dietary pattern; LIHC cis rs9534288 0.730 rs2148412 chr13:46595849 C/T cg15192986 chr13:46630673 CPB2 -0.48 -7.28 -0.37 2.34e-12 Blood protein levels; LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.593 rs16921589 chr8:58024387 C/A cg02290350 chr8:58132656 NA 0.3 6.85 0.35 3.41e-11 Developmental language disorder (linguistic errors); LIHC cis rs7520050 0.966 rs12049588 chr1:46472422 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.0 0.31 4.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg11342453 chr6:26196699 NA 0.53 5.92 0.3 7.83e-9 Gout;Renal underexcretion gout; LIHC cis rs17685 0.587 rs1623759 chr7:75724679 A/T cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.37e-16 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs61931739 0.500 rs11053211 chr12:34464334 T/C cg26384229 chr12:38710491 ALG10B 0.63 7.99 0.4 2.15e-14 Morning vs. evening chronotype; LIHC cis rs1799949 0.929 rs799906 chr17:41278116 T/C cg23758822 chr17:41437982 NA 0.91 16.8 0.67 1.33e-46 Menopause (age at onset); LIHC cis rs6665290 0.669 rs6426558 chr1:227175367 G/T cg10327440 chr1:227177885 CDC42BPA -1.13 -26.39 -0.82 1.66e-84 Myeloid white cell count; LIHC cis rs67478160 0.643 rs7156697 chr14:104211136 G/A cg01849466 chr14:104193079 ZFYVE21 -0.44 -7.07 -0.36 8.59e-12 Schizophrenia; LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg03735888 chr19:58951602 ZNF132 0.4 7.11 0.36 6.68e-12 Uric acid clearance; LIHC cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg11890956 chr21:40555474 PSMG1 -0.51 -8.41 -0.41 1.13e-15 Menarche (age at onset); LIHC cis rs6582630 0.555 rs11182148 chr12:38464883 A/C cg13010199 chr12:38710504 ALG10B 0.43 5.8 0.3 1.54e-8 Drug-induced liver injury (flucloxacillin); LIHC trans rs2727020 0.523 rs7948958 chr11:49506749 G/A cg18944383 chr4:111397179 ENPEP -0.35 -8.19 -0.4 5.43e-15 Coronary artery disease; LIHC cis rs2997447 0.723 rs2802337 chr1:26474398 G/C cg19633962 chr1:26362018 EXTL1 -0.54 -6.33 -0.32 7.49e-10 QRS complex (12-leadsum); LIHC cis rs6840360 0.615 rs10001603 chr4:152647577 T/A cg22705602 chr4:152727874 NA -0.41 -8.57 -0.42 3.72e-16 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.964 rs3799373 chr6:25929173 A/C cg03517284 chr6:25882590 NA -0.39 -5.9 -0.3 8.72e-9 Height; LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg08219700 chr8:58056026 NA 0.52 7.14 0.36 5.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs8060686 0.545 rs11043 chr16:68262958 G/A cg09835421 chr16:68378352 PRMT7 -0.5 -5.94 -0.31 7.02e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs7020830 0.898 rs308521 chr9:37367094 T/C cg14294708 chr9:37120828 ZCCHC7 0.87 16.49 0.67 2.27e-45 Schizophrenia; LIHC cis rs2180341 0.960 rs7766802 chr6:127709871 T/G cg24812749 chr6:127587940 RNF146 1.04 15.73 0.65 2.54e-42 Breast cancer; LIHC cis rs11585357 0.843 rs12095095 chr1:17625832 C/G cg08277548 chr1:17600880 PADI3 -0.61 -6.71 -0.34 8.22e-11 Hair shape; LIHC cis rs7772486 0.641 rs2253757 chr6:146199686 C/T cg13319975 chr6:146136371 FBXO30 -0.57 -9.03 -0.44 1.3e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs11146838 1 rs11146838 chr10:39149977 A/T cg17219203 chr10:38645113 HSD17B7P2 -0.45 -6.49 -0.33 2.94e-10 Breast cancer; LIHC cis rs425535 0.619 rs3906613 chr4:74828447 G/A cg02530824 chr4:74847766 PF4 -0.37 -5.95 -0.31 6.57e-9 Blood protein levels; LIHC trans rs1864585 0.505 rs73208792 chr8:10680471 C/T cg26278703 chr11:58910052 FAM111A 0.74 6.69 0.34 9.38e-11 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs80282103 0.867 rs7098169 chr10:1078601 G/A cg18964960 chr10:1102726 WDR37 0.67 6.31 0.32 8.41e-10 Glomerular filtration rate (creatinine); LIHC cis rs4555082 0.874 rs28625632 chr14:105748849 G/T cg06808227 chr14:105710500 BRF1 -0.57 -7.6 -0.38 2.89e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs936229 0.861 rs7180484 chr15:75115416 G/T cg14664628 chr15:75095509 CSK 1.0 19.63 0.73 5.46e-58 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs4919087 0.545 rs793531 chr10:99041167 G/T cg25902810 chr10:99078978 FRAT1 -0.6 -6.68 -0.34 9.74e-11 Monocyte count; LIHC cis rs9457247 0.765 rs6900701 chr6:167434112 A/G cg23791538 chr6:167370224 RNASET2 -0.51 -7.94 -0.39 2.85e-14 Crohn's disease; LIHC cis rs3793683 0.965 rs3829131 chr10:134564627 A/G cg06453172 chr10:134556979 INPP5A 0.57 8.04 0.4 1.47e-14 Migraine; LIHC cis rs6545883 0.894 rs2694634 chr2:61551435 T/C cg14146966 chr2:61757674 XPO1 -0.43 -7.3 -0.37 2.04e-12 Tuberculosis; LIHC cis rs78456975 1.000 rs6712176 chr2:1556393 C/T cg01028140 chr2:1542097 TPO -0.53 -6.3 -0.32 8.92e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1801251 1.000 rs1801251 chr2:233633460 G/A cg25237894 chr2:233734115 C2orf82 0.58 11.25 0.52 3.32e-25 Coronary artery disease; LIHC cis rs17685 0.753 rs1637037 chr7:75692927 C/T cg01364799 chr7:75623366 TMEM120A -0.51 -7.81 -0.39 6.99e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs311392 0.902 rs411839 chr8:55092189 T/C cg11783602 chr8:55087084 NA -0.31 -6.09 -0.31 3.02e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs11122272 0.735 rs2749717 chr1:231489353 G/T cg06096015 chr1:231504339 EGLN1 0.49 9.29 0.45 1.9e-18 Hemoglobin concentration; LIHC cis rs861020 0.563 rs12046618 chr1:210043135 C/T cg09163369 chr1:210001066 C1orf107 0.48 5.71 0.3 2.44e-8 Orofacial clefts; LIHC cis rs950169 0.544 rs62021193 chr15:85170583 C/G cg17507749 chr15:85114479 UBE2QP1 0.69 7.99 0.4 2.07e-14 Schizophrenia; LIHC cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg11644478 chr21:40555479 PSMG1 0.83 10.86 0.51 8.58e-24 Cognitive function; LIHC cis rs7617773 0.539 rs17593974 chr3:48387334 G/T cg11946769 chr3:48343235 NME6 0.6 7.38 0.37 1.24e-12 Coronary artery disease; LIHC cis rs875971 1.000 rs1363055 chr7:65943275 A/G cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs965469 0.779 rs6037548 chr20:3299299 G/A cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs2153535 0.580 rs9406143 chr6:8444583 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs6586163 0.843 rs7069061 chr10:90754909 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.57 -8.36 -0.41 1.64e-15 Chronic lymphocytic leukemia; LIHC cis rs6088590 0.710 rs6059992 chr20:33282275 T/C cg08999081 chr20:33150536 PIGU 0.59 10.79 0.5 1.47e-23 Coronary artery disease; LIHC cis rs801193 0.660 rs1016265 chr7:66214567 C/T cg18876405 chr7:65276391 NA 0.33 6.05 0.31 3.87e-9 Aortic root size; LIHC cis rs7945705 0.869 rs4909952 chr11:8963946 A/G cg12365402 chr11:9010492 NRIP3 0.31 7.97 0.4 2.37e-14 Hemoglobin concentration; LIHC cis rs35110281 0.748 rs162403 chr21:44963365 C/G cg04455712 chr21:45112962 RRP1B 0.46 7.67 0.38 1.82e-13 Mean corpuscular volume; LIHC cis rs6963495 0.818 rs73190166 chr7:105159955 G/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2070433 0.706 rs55696586 chr21:47733918 T/C cg12379764 chr21:47803548 PCNT 0.71 7.97 0.4 2.41e-14 Lymphocyte counts; LIHC cis rs797680 0.856 rs7547244 chr1:93781768 A/G cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.04 -0.31 3.95e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs116095464 0.558 rs55838121 chr5:266890 G/A cg22496380 chr5:211416 CCDC127 -1.05 -10.66 -0.5 4.14e-23 Breast cancer; LIHC cis rs2230307 0.656 rs1395332 chr1:100503993 A/C cg24955406 chr1:100503596 HIAT1 0.62 6.13 0.31 2.44e-9 Carotid intima media thickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24376286 chr2:198245629 NA 0.34 6.36 0.33 6.28e-10 Pancreatic cancer; LIHC cis rs1799949 0.965 rs799912 chr17:41257134 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.19 0.32 1.7e-9 Menopause (age at onset); LIHC cis rs11969893 0.649 rs9498408 chr6:101292340 C/T cg12253828 chr6:101329408 ASCC3 0.94 12.07 0.55 3.4e-28 Economic and political preferences (immigration/crime); LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg22963979 chr7:1858916 MAD1L1 -0.46 -7.72 -0.39 1.34e-13 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg00280220 chr17:61926910 NA 0.43 6.89 0.35 2.71e-11 Prudent dietary pattern; LIHC cis rs7216064 0.953 rs11079705 chr17:65835452 A/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.34 -0.45 1.31e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs66887589 0.592 rs11731571 chr4:120221185 G/A cg25214090 chr10:38739885 LOC399744 0.44 6.91 0.35 2.32e-11 Diastolic blood pressure; LIHC trans rs208520 0.779 rs208451 chr6:66906155 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.71 -7.65 -0.38 2.05e-13 Exhaled nitric oxide output; LIHC cis rs7534824 0.625 rs3087816 chr1:101441775 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 6.93 0.35 2.07e-11 Refractive astigmatism; LIHC cis rs5769765 1.000 rs4824112 chr22:50284345 A/G cg09182678 chr22:50328711 NA -0.43 -6.16 -0.32 2.04e-9 Schizophrenia; LIHC cis rs7520050 0.902 rs1355642 chr1:46598903 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.23 0.32 1.34e-9 Red blood cell count;Reticulocyte count; LIHC trans rs1994135 0.669 rs11052747 chr12:33697913 C/G cg26384229 chr12:38710491 ALG10B 0.46 6.21 0.32 1.54e-9 Resting heart rate; LIHC cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg02353165 chr6:42928485 GNMT 0.94 15.25 0.64 2e-40 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1816752 0.870 rs8000215 chr13:25009786 A/G cg22771759 chr13:24902376 NA 0.32 6.7 0.34 8.43e-11 Obesity-related traits; LIHC cis rs1461503 0.966 rs7113725 chr11:122843511 G/T cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs79387448 0.701 rs11465596 chr2:102987093 C/A cg09003973 chr2:102972529 NA 1.22 9.95 0.47 1.15e-20 Gut microbiota (bacterial taxa); LIHC cis rs7572733 0.555 rs2342558 chr2:198920142 T/C cg10820045 chr2:198174542 NA 0.41 6.04 0.31 4.05e-9 Dermatomyositis; LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs3008870 0.755 rs4655661 chr1:67408828 A/C cg02640540 chr1:67518911 SLC35D1 0.41 6.38 0.33 5.76e-10 Lymphocyte percentage of white cells; LIHC cis rs7927771 0.864 rs60075622 chr11:47449101 T/G cg20135002 chr11:47629003 NA -0.56 -9.44 -0.45 6.07e-19 Subjective well-being; LIHC cis rs722599 0.748 rs3742783 chr14:75377008 C/T cg08847533 chr14:75593920 NEK9 -0.54 -8.98 -0.44 1.88e-17 IgG glycosylation; LIHC cis rs727505 1.000 rs66665074 chr7:124550526 C/T cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.1e-9 Lewy body disease; LIHC trans rs1814175 0.645 rs28549248 chr11:50042740 C/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs6088580 0.524 rs6142210 chr20:33223012 C/T cg07148914 chr20:33460835 GGT7 -0.5 -7.14 -0.36 5.67e-12 Glomerular filtration rate (creatinine); LIHC cis rs9303401 0.659 rs3809724 chr17:57061238 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.95 12.66 0.56 2.21e-30 Cognitive test performance; LIHC cis rs4423214 1.000 rs12793530 chr11:71161656 G/A cg05163923 chr11:71159392 DHCR7 0.93 14.4 0.61 4.4e-37 Vitamin D levels; LIHC cis rs7613875 0.580 rs2624819 chr3:50010571 G/T cg05623727 chr3:50126028 RBM5 0.33 5.8 0.3 1.48e-8 Body mass index; LIHC cis rs1712517 0.873 rs1712516 chr10:105033628 G/A cg05636881 chr10:105038444 INA 0.42 6.48 0.33 3.25e-10 Migraine; LIHC cis rs2708977 0.966 rs749027 chr2:97203137 A/C cg01950434 chr2:97203154 ARID5A -0.54 -8.16 -0.4 6.28e-15 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs67311347 0.869 rs7646899 chr3:40366982 A/G cg16822855 chr3:40428330 ENTPD3 0.34 6.12 0.31 2.56e-9 Renal cell carcinoma; LIHC trans rs2832191 0.692 rs8134627 chr21:30349069 C/T cg14791747 chr16:20752902 THUMPD1 0.49 6.84 0.35 3.76e-11 Dental caries; LIHC cis rs6570726 0.599 rs426371 chr6:145886469 A/G cg23711669 chr6:146136114 FBXO30 -0.65 -10.42 -0.49 2.9e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg04267008 chr7:1944627 MAD1L1 -0.59 -8.96 -0.44 2.1e-17 Bipolar disorder and schizophrenia; LIHC cis rs7537052 0.669 rs4652903 chr1:36642858 C/T cg24686825 chr1:36642396 MAP7D1 -0.46 -8.52 -0.42 5.01e-16 Schizophrenia; LIHC cis rs6061231 0.837 rs6121558 chr20:60961365 A/G cg06026331 chr20:60912101 LAMA5 0.52 7.17 0.36 4.71e-12 Colorectal cancer; LIHC cis rs8180040 0.726 rs4682842 chr3:46982773 C/G cg16586182 chr3:47516702 SCAP 0.5 8.83 0.43 5.53e-17 Colorectal cancer; LIHC cis rs2274273 0.840 rs10142448 chr14:55838108 G/T cg01864836 chr14:55583639 NA 0.35 6.57 0.33 1.87e-10 Protein biomarker; LIHC cis rs60871478 1.000 rs62432252 chr7:802886 C/G cg27478167 chr7:817139 HEATR2 -0.42 -6.01 -0.31 4.77e-9 Cerebrospinal P-tau181p levels; LIHC cis rs9381040 0.610 rs2235679 chr6:41020577 G/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.16 -0.32 2.1e-9 Alzheimer's disease (late onset); LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg19318889 chr4:1322082 MAEA 0.66 10.44 0.49 2.55e-22 Longevity; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.68 9.98 0.47 9.22e-21 Lymphocyte counts; LIHC cis rs12478296 0.786 rs13409307 chr2:242995499 G/C cg06360820 chr2:242988706 NA -0.84 -13.19 -0.58 2.14e-32 Obesity-related traits; LIHC cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs9633740 1.000 rs7097656 chr10:82250831 T/C cg01528321 chr10:82214614 TSPAN14 0.93 12.07 0.55 3.51e-28 Post bronchodilator FEV1; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07024458 chr16:56390600 GNAO1 0.45 6.65 0.34 1.16e-10 Pancreatic cancer; LIHC cis rs67311347 0.713 rs114569261 chr3:40314580 G/A cg18306943 chr3:40428807 ENTPD3 0.38 6.44 0.33 4.02e-10 Renal cell carcinoma; LIHC cis rs709400 0.627 rs55859054 chr14:103953666 T/A cg26031613 chr14:104095156 KLC1 0.72 9.07 0.44 9.36e-18 Body mass index; LIHC cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1707322 0.717 rs2253862 chr1:46081960 C/T cg06784218 chr1:46089804 CCDC17 -0.41 -7.45 -0.37 7.94e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7829975 0.511 rs2976902 chr8:8341105 T/G cg08975724 chr8:8085496 FLJ10661 0.41 5.96 0.31 6.3e-9 Mood instability; LIHC trans rs66573146 0.634 rs55633489 chr4:6988745 C/A cg07817883 chr1:32538562 TMEM39B 1.14 9.55 0.46 2.67e-19 Granulocyte percentage of myeloid white cells; LIHC trans rs9747201 1.000 rs67588022 chr17:80176071 G/A cg07393940 chr7:158741817 NA 0.55 6.37 0.33 6.26e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2204008 0.720 rs11170774 chr12:38021722 C/T cg26384229 chr12:38710491 ALG10B -0.48 -6.72 -0.34 7.58e-11 Bladder cancer; LIHC cis rs2235642 0.533 rs17135391 chr16:1605606 C/T cg03034668 chr16:1723424 CRAMP1L -0.41 -6.43 -0.33 4.32e-10 Coronary artery disease; LIHC cis rs6815814 0.678 rs9715841 chr4:38774503 T/C cg06935464 chr4:38784597 TLR10 0.38 5.94 0.31 7.12e-9 Breast cancer; LIHC cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg16405210 chr4:1374714 KIAA1530 0.7 10.48 0.49 1.76e-22 Obesity-related traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11952604 chr15:69113456 ANP32A -0.53 -6.14 -0.32 2.3e-9 Systolic blood pressure; LIHC cis rs6456156 0.586 rs7742305 chr6:167485723 C/T cg12798992 chr6:167411361 FGFR1OP 0.44 6.65 0.34 1.13e-10 Primary biliary cholangitis; LIHC cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg00656387 chr3:40428638 ENTPD3 -0.45 -7.64 -0.38 2.26e-13 Renal cell carcinoma; LIHC cis rs7520050 0.966 rs11211230 chr1:46406767 G/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.86 0.3 1.08e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2334880 0.638 rs17343777 chr16:71439172 T/A cg06353428 chr16:71660113 MARVELD3 -0.88 -7.72 -0.39 1.3e-13 Malaria; LIHC cis rs1552244 0.626 rs2886396 chr3:10037670 C/T cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs754466 0.606 rs56402185 chr10:79585848 G/A cg17075019 chr10:79541650 NA -0.79 -12.2 -0.55 1.17e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.77 -0.34 5.79e-11 Lymphocyte counts; LIHC cis rs6762 0.748 rs28551040 chr11:840740 G/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.81 -9.62 -0.46 1.56e-19 Mean platelet volume; LIHC cis rs35110281 0.713 rs1378079 chr21:45011187 A/G cg21573476 chr21:45109991 RRP1B -0.52 -9.72 -0.47 7.09e-20 Mean corpuscular volume; LIHC cis rs921968 0.608 rs832817 chr2:219358603 C/T cg17980119 chr2:219472607 PLCD4 0.36 6.21 0.32 1.55e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs763121 0.853 rs5757232 chr22:39071677 C/T cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs9399135 0.935 rs11759999 chr6:135370495 G/T cg24558204 chr6:135376177 HBS1L 0.45 7.25 0.37 2.78e-12 Red blood cell count; LIHC cis rs5769765 0.773 rs6520065 chr22:50294470 A/T cg02269571 chr22:50332266 NA -0.61 -8.7 -0.43 1.44e-16 Schizophrenia; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.86e-9 Total body bone mineral density; LIHC cis rs17854409 0.881 rs1046784 chr20:61472808 G/C cg06598544 chr20:61472147 COL9A3 -0.9 -8.58 -0.42 3.3e-16 Obesity-related traits; LIHC cis rs6762 0.719 rs28620453 chr11:836971 G/C cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.58 -0.46 2e-19 Mean platelet volume; LIHC cis rs12477438 0.798 rs13409996 chr2:99575497 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.95 -0.47 1.22e-20 Chronic sinus infection; LIHC cis rs561341 0.739 rs4795663 chr17:30214542 T/C cg13647721 chr17:30228624 UTP6 -0.73 -8.63 -0.42 2.35e-16 Hip circumference adjusted for BMI; LIHC trans rs9929218 1.000 rs4783681 chr16:68806508 C/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs9311474 0.632 rs6445528 chr3:52572447 C/T cg10802521 chr3:52805072 NEK4 0.41 6.95 0.35 1.85e-11 Electroencephalogram traits; LIHC cis rs3781684 1.000 rs2233551 chr11:76814471 A/G cg19164997 chr11:76818702 CAPN5 -0.42 -5.92 -0.3 7.92e-9 Cognitive performance; LIHC cis rs17253792 0.822 rs28513551 chr14:56094993 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs7772486 0.790 rs2249147 chr6:146184999 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.86 0.3 1.09e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.645 rs11040661 chr11:49952146 G/T cg15704280 chr7:45808275 SEPT13 -0.96 -19.79 -0.73 1.21e-58 Height; LIHC cis rs1982963 1.000 rs1982963 chr14:52509101 C/T cg10843707 chr14:52510701 NID2 -0.47 -8.37 -0.41 1.5e-15 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs77637988 0.604 rs7566239 chr2:48598882 G/A cg00032884 chr2:48540671 FOXN2 0.4 6.33 0.32 7.64e-10 Joint mobility (Beighton score); LIHC cis rs7772486 0.875 rs9390371 chr6:146363180 A/G cg13319975 chr6:146136371 FBXO30 -0.34 -5.81 -0.3 1.45e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9322817 0.691 rs2400071 chr6:105344075 C/T cg02098413 chr6:105308735 HACE1 0.42 7.96 0.4 2.52e-14 Thyroid stimulating hormone; LIHC cis rs9814567 1.000 rs1917130 chr3:134313773 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.91 0.3 8.38e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs72627123 0.867 rs73303116 chr14:74483615 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.56 0.46 2.44e-19 Morning vs. evening chronotype; LIHC cis rs7772486 0.846 rs1854901 chr6:146325685 T/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.83 -0.3 1.28e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.935 rs10839329 chr11:49694206 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -21.62 -0.76 6.02e-66 Height; LIHC cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg04944784 chr2:26401820 FAM59B 0.72 9.18 0.44 4.2e-18 Mean corpuscular hemoglobin; LIHC cis rs61041384 0.661 rs4148864 chr12:123580657 C/T cg25930673 chr12:123319894 HIP1R 0.65 6.08 0.31 3.2e-9 Schizophrenia; LIHC cis rs4665809 1.000 rs6546726 chr2:26275116 A/G cg27170947 chr2:26402098 FAM59B -0.63 -7.79 -0.39 7.86e-14 Gut microbiome composition (summer); LIHC cis rs12711979 0.509 rs1031478 chr2:3827425 G/A cg17052675 chr2:3827356 NA -0.72 -16.2 -0.66 3.33e-44 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs11190604 1.000 rs7071271 chr10:102264824 G/A cg07080220 chr10:102295463 HIF1AN 0.57 8.24 0.41 3.65e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg13397359 chr6:42928475 GNMT 0.7 10.21 0.48 1.59e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4975616 0.836 rs13178866 chr5:1323212 C/T cg06550200 chr5:1325588 CLPTM1L -0.68 -10.9 -0.51 6.28e-24 Lung cancer; LIHC cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg10862848 chr6:42927986 GNMT -0.3 -6.69 -0.34 9.2e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9513627 1.000 rs2390279 chr13:100208705 A/G cg25919922 chr13:100150906 NA -0.73 -6.97 -0.35 1.62e-11 Obesity-related traits; LIHC cis rs12079745 0.793 rs114369903 chr1:169251394 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -6.79 -0.34 5.08e-11 QT interval; LIHC cis rs2576037 0.583 rs8096263 chr18:44515216 C/T cg19077165 chr18:44547161 KATNAL2 -0.44 -6.82 -0.35 4.13e-11 Personality dimensions; LIHC cis rs4728302 0.869 rs6467510 chr7:133607968 A/G cg10665199 chr7:133106180 EXOC4 0.38 6.72 0.34 7.63e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs1577917 0.771 rs7452605 chr6:86240951 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 8.11 0.4 9.35e-15 Response to antipsychotic treatment; LIHC cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg11644478 chr21:40555479 PSMG1 0.84 10.9 0.51 6e-24 Cognitive function; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg22272508 chr17:34961264 MRM1 0.57 6.08 0.31 3.2e-9 Mean platelet volume; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg01087294 chr15:90456194 C15orf38 -0.39 -6.13 -0.31 2.36e-9 Immature fraction of reticulocytes; LIHC cis rs2806561 0.704 rs663942 chr1:23522476 G/A cg19743168 chr1:23544995 NA 0.38 6.32 0.32 8.35e-10 Height; LIHC cis rs60871478 1.000 rs62432251 chr7:801855 T/G cg04727924 chr7:799746 HEATR2 -0.57 -8.42 -0.41 1.02e-15 Cerebrospinal P-tau181p levels; LIHC cis rs34779708 0.966 rs17499811 chr10:35456215 G/A cg04310649 chr10:35416472 CREM -0.42 -5.76 -0.3 1.91e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3812111 0.774 rs564253 chr6:116424714 C/T cg08036074 chr6:116424633 NT5DC1 -0.67 -12.11 -0.55 2.5e-28 Age-related macular degeneration; LIHC cis rs6430585 0.528 rs309152 chr2:136657252 C/T cg07169764 chr2:136633963 MCM6 -0.92 -13.68 -0.59 2.89e-34 Corneal structure; LIHC cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg13397359 chr6:42928475 GNMT 0.78 11.25 0.52 3.39e-25 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3806843 0.676 rs2245643 chr5:140029780 C/T cg19875535 chr5:140030758 IK -0.44 -7.42 -0.37 9.51e-13 Depressive symptoms (multi-trait analysis); LIHC cis rs600806 0.778 rs4970765 chr1:110009171 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.36 -0.33 6.47e-10 Intelligence (multi-trait analysis); LIHC trans rs2739330 0.796 rs5760106 chr22:24250645 A/C cg06437703 chr8:37914619 EIF4EBP1 0.52 8.17 0.4 5.95e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3008870 0.755 rs6657065 chr1:67384639 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.69 0.5 3.44e-23 Lymphocyte percentage of white cells; LIHC cis rs61712019 0.679 rs11126613 chr2:77722435 C/T cg11252801 chr2:77748917 LRRTM4 0.56 7.73 0.39 1.2e-13 Schizophrenia; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg11494091 chr17:61959527 GH2 0.46 8.48 0.42 6.72e-16 Prudent dietary pattern; LIHC cis rs6912958 0.781 rs2300906 chr6:88207155 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.03 -0.4 1.57e-14 Monocyte percentage of white cells; LIHC cis rs11671005 0.570 rs73062110 chr19:58936642 G/T cg25952890 chr19:58913133 NA 0.68 7.37 0.37 1.26e-12 Mean platelet volume; LIHC cis rs422249 0.512 rs174554 chr11:61579463 A/G cg07689907 chr11:61582574 FADS1 0.39 5.77 0.3 1.78e-8 Trans fatty acid levels; LIHC cis rs11785400 1.000 rs11776301 chr8:143737142 A/G cg10596483 chr8:143751796 JRK 0.51 8.38 0.41 1.37e-15 Schizophrenia; LIHC cis rs11122272 0.668 rs1538664 chr1:231555295 C/T cg06096015 chr1:231504339 EGLN1 0.48 9.09 0.44 8.04e-18 Hemoglobin concentration; LIHC cis rs9399135 0.967 rs2150681 chr6:135375232 A/G cg24558204 chr6:135376177 HBS1L -0.45 -7.28 -0.37 2.25e-12 Red blood cell count; LIHC cis rs611744 0.905 rs408506 chr8:109154233 A/C cg18478394 chr8:109455254 TTC35 -0.35 -6.05 -0.31 3.82e-9 Dupuytren's disease; LIHC cis rs7659604 0.676 rs4077102 chr4:122699830 A/G cg20573242 chr4:122745356 CCNA2 0.51 7.44 0.37 8.19e-13 Type 2 diabetes; LIHC cis rs1878931 0.559 rs11643501 chr16:3392752 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.58 7.71 0.38 1.36e-13 Body mass index (adult); LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg21782813 chr7:2030301 MAD1L1 0.56 10.27 0.49 9.91e-22 Bipolar disorder and schizophrenia; LIHC cis rs2115630 0.645 rs4842978 chr15:85197253 T/C cg12501888 chr15:85177176 SCAND2 -0.47 -7.03 -0.36 1.12e-11 P wave terminal force; LIHC cis rs6430585 0.527 rs76622824 chr2:136411879 A/G cg07169764 chr2:136633963 MCM6 0.69 8.77 0.43 8.56e-17 Corneal structure; LIHC cis rs896854 0.654 rs896847 chr8:95972551 G/A cg13393036 chr8:95962371 TP53INP1 -0.37 -8.55 -0.42 4.1e-16 Type 2 diabetes; LIHC trans rs12478296 0.685 rs6705935 chr2:242995110 C/T cg01596870 chr19:55963115 NA -0.65 -9.28 -0.45 1.99e-18 Obesity-related traits; LIHC cis rs752010 0.714 rs2148635 chr1:42082452 C/T cg06885757 chr1:42089581 HIVEP3 -0.3 -6.15 -0.32 2.2e-9 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.76e-9 Menopause (age at onset); LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg11062466 chr8:58055876 NA 0.49 7.25 0.37 2.78e-12 Developmental language disorder (linguistic errors); LIHC cis rs853679 0.517 rs9468286 chr6:28079428 C/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs6977660 0.714 rs17141945 chr7:19805056 T/A cg07541023 chr7:19748670 TWISTNB 0.39 5.83 0.3 1.29e-8 Thyroid stimulating hormone; LIHC trans rs1814175 0.562 rs1794130 chr11:49903764 T/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs4716602 0.596 rs10270517 chr7:156160010 A/G cg16983916 chr7:156159713 NA -0.32 -5.71 -0.3 2.43e-8 Anti-saccade response; LIHC cis rs12477438 0.501 rs11692336 chr2:99740606 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs7666738 0.791 rs10856934 chr4:99010844 A/G cg17366294 chr4:99064904 C4orf37 -0.37 -5.82 -0.3 1.33e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg19318889 chr4:1322082 MAEA 0.46 6.49 0.33 3.11e-10 Obesity-related traits; LIHC cis rs12458462 0.851 rs60298379 chr18:77488422 C/T cg11879182 chr18:77439856 CTDP1 0.83 13.38 0.59 4.01e-33 Monocyte count; LIHC cis rs10078 0.571 rs890977 chr5:476910 T/C cg07599136 chr5:415885 AHRR 0.78 12.76 0.57 8.79e-31 Fat distribution (HIV); LIHC cis rs17125944 0.686 rs77625717 chr14:53336544 T/C cg00686598 chr14:53173677 PSMC6 0.87 9.54 0.46 2.85e-19 Alzheimer's disease (late onset); LIHC cis rs919433 0.889 rs10931782 chr2:198211579 G/A cg10820045 chr2:198174542 NA -0.57 -9.34 -0.45 1.24e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1941023 0.584 rs10750937 chr11:60172087 C/T cg08716584 chr11:60157161 MS4A7 -0.36 -8.25 -0.41 3.45e-15 Congenital heart disease (maternal effect); LIHC cis rs7208859 0.562 rs216408 chr17:28907757 C/G cg13385521 chr17:29058706 SUZ12P -0.58 -5.86 -0.3 1.08e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs9940464 0.871 rs12597099 chr16:83366896 C/G cg13016115 chr14:23388406 RBM23 0.38 6.16 0.32 2.09e-9 Malaria; LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg14004847 chr7:1930337 MAD1L1 -0.42 -5.91 -0.3 8.35e-9 Bipolar disorder and schizophrenia; LIHC cis rs11676855 0.924 rs11680626 chr2:235927511 A/T cg02447239 chr2:235936137 SH3BP4 0.36 6.36 0.33 6.58e-10 Dialysis-related mortality; LIHC cis rs2180341 0.920 rs9401951 chr6:127671632 A/C cg27446573 chr6:127587934 RNF146 1.06 16.62 0.67 6.67e-46 Breast cancer; LIHC cis rs35306767 0.903 rs11815185 chr10:923617 T/A cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.7 12.62 0.56 3.12e-30 Prudent dietary pattern; LIHC cis rs2204008 0.837 rs11172728 chr12:38070042 C/A cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC cis rs9837602 0.529 rs793494 chr3:99508768 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.97 0.35 1.68e-11 Breast cancer; LIHC cis rs9309711 0.621 rs7586472 chr2:3473670 G/A cg15506890 chr2:3487001 NA -0.46 -7.25 -0.36 2.82e-12 Neurofibrillary tangles; LIHC cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg18357526 chr6:26021779 HIST1H4A 0.6 8.44 0.42 8.94e-16 Blood metabolite levels; LIHC cis rs2932538 0.922 rs7522110 chr1:113072914 A/C cg22162597 chr1:113214053 CAPZA1 0.69 10.74 0.5 2.24e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg00149659 chr3:10157352 C3orf10 0.66 6.49 0.33 2.94e-10 Alzheimer's disease; LIHC cis rs6076065 0.802 rs2424527 chr20:23357329 A/C cg11657817 chr20:23433608 CST11 0.32 6.75 0.34 6.52e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs6582630 0.519 rs11609739 chr12:38547969 G/A cg26384229 chr12:38710491 ALG10B 0.97 12.69 0.57 1.64e-30 Drug-induced liver injury (flucloxacillin); LIHC cis rs599083 0.530 rs583545 chr11:68178635 T/C cg01657329 chr11:68192670 LRP5 0.58 7.84 0.39 5.93e-14 Bone mineral density (spine); LIHC cis rs6748734 1.000 rs4293565 chr2:241834770 A/G cg08694578 chr2:241835147 C2orf54 -0.51 -7.18 -0.36 4.38e-12 Urinary metabolites; LIHC cis rs904251 0.766 rs1757175 chr6:37486694 T/C cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.47e-9 Cognitive performance; LIHC cis rs7100689 0.622 rs7090351 chr10:82142047 T/G cg00277334 chr10:82204260 NA -0.59 -7.63 -0.38 2.3e-13 Post bronchodilator FEV1; LIHC cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg11965913 chr1:205819406 PM20D1 0.68 9.93 0.47 1.42e-20 Menarche (age at onset); LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg10774155 chr7:65338427 VKORC1L1 0.45 6.82 0.35 4.12e-11 Calcium levels; LIHC cis rs11190604 1.000 rs2495742 chr10:102331364 C/T cg07080220 chr10:102295463 HIF1AN 0.56 7.79 0.39 8.28e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg05484376 chr2:27715224 FNDC4 0.39 6.61 0.34 1.46e-10 Total body bone mineral density; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg21747090 chr2:27597821 SNX17 -0.44 -6.71 -0.34 8.05e-11 Total body bone mineral density; LIHC cis rs2071426 0.959 rs1934955 chr10:96788561 A/G cg09036531 chr10:96991505 NA -0.5 -5.91 -0.3 8.38e-9 Blood metabolite levels; LIHC cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg10360139 chr7:1886902 MAD1L1 -0.38 -5.88 -0.3 9.71e-9 Bipolar disorder and schizophrenia; LIHC cis rs2963155 0.518 rs258748 chr5:142656454 C/G cg17617527 chr5:142782415 NR3C1 0.93 10.88 0.51 7.18e-24 Breast cancer; LIHC cis rs13191362 0.935 rs66962088 chr6:162963891 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.72 6.19 0.32 1.68e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1451375 0.642 rs6963996 chr7:50559300 T/C cg14593290 chr7:50529359 DDC -0.62 -10.18 -0.48 1.88e-21 Malaria; LIHC cis rs6598955 0.543 rs3795689 chr1:26560366 C/G cg04990556 chr1:26633338 UBXN11 0.75 11.3 0.52 2.26e-25 Obesity-related traits; LIHC cis rs926392 0.640 rs4616534 chr20:37693564 G/A cg16355469 chr20:37678765 NA 0.49 7.07 0.36 8.55e-12 Dialysis-related mortality; LIHC cis rs11711311 1.000 rs12497716 chr3:113453258 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.42 -0.37 9.42e-13 IgG glycosylation; LIHC cis rs249954 0.512 rs249867 chr16:23668568 G/A cg05131483 chr16:23706242 ERN2 0.38 6.3 0.32 8.91e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs782590 0.721 rs1084525 chr2:55929430 C/T cg18811423 chr2:55921094 PNPT1 0.98 15.32 0.64 1.03e-40 Metabolic syndrome; LIHC cis rs9291683 0.552 rs10939656 chr4:10014646 A/C cg11266682 chr4:10021025 SLC2A9 0.33 7.05 0.36 9.84e-12 Bone mineral density; LIHC cis rs651907 0.557 rs7612283 chr3:101434919 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.46 0.53 5.85e-26 Colorectal cancer; LIHC cis rs6430585 1.000 rs6430585 chr2:136506927 A/C cg07169764 chr2:136633963 MCM6 -1.0 -14.71 -0.62 2.7e-38 Corneal structure; LIHC cis rs6952808 0.760 rs11764960 chr7:1950532 G/A cg04267008 chr7:1944627 MAD1L1 -0.73 -11.64 -0.53 1.27e-26 Bipolar disorder and schizophrenia; LIHC cis rs7772486 0.902 rs1125462 chr6:146417832 A/G cg23711669 chr6:146136114 FBXO30 0.53 9.36 0.45 1.11e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg11764359 chr7:65958608 NA 0.57 5.99 0.31 5.39e-9 Diabetic kidney disease; LIHC trans rs1864585 0.520 rs73208791 chr8:10680338 T/C cg26278703 chr11:58910052 FAM111A 0.74 6.83 0.35 3.95e-11 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg02187348 chr16:89574699 SPG7 0.5 7.48 0.38 6.2800000000000005e-13 Multiple myeloma (IgH translocation); LIHC cis rs912057 1.000 rs1294407 chr6:6738103 C/G cg06612196 chr6:6737390 NA 0.54 9.84 0.47 2.83e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs6456156 0.526 rs1854853 chr6:167533062 A/G cg07741184 chr6:167504864 NA -0.24 -5.91 -0.3 8.23e-9 Primary biliary cholangitis; LIHC cis rs7208859 0.573 rs73267829 chr17:29003939 G/A cg13385521 chr17:29058706 SUZ12P 0.66 6.27 0.32 1.1e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8072100 0.817 rs11869940 chr17:45578435 T/A cg08085267 chr17:45401833 C17orf57 0.38 5.75 0.3 1.94e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs637571 0.544 rs617791 chr11:65702523 C/G cg17712092 chr4:129076599 LARP1B 0.75 12.04 0.55 4.32e-28 Eosinophil percentage of white cells; LIHC cis rs6502050 0.835 rs8066284 chr17:80127825 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs637571 0.522 rs1151512 chr11:65757533 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.4 6.02 0.31 4.48e-9 Eosinophil percentage of white cells; LIHC cis rs10508774 1.000 rs58783140 chr10:32909603 C/T cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.1 -16.0 -0.65 2.15e-43 Gut microbiome composition (summer); LIHC cis rs700651 0.753 rs10207232 chr2:198893813 A/G cg03934865 chr2:198174659 NA 0.46 6.53 0.33 2.36e-10 Intracranial aneurysm; LIHC cis rs7772486 0.790 rs1133832 chr6:146205604 C/T cg23711669 chr6:146136114 FBXO30 -0.6 -10.59 -0.5 7.25e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg00280220 chr17:61926910 NA 0.44 7.07 0.36 8.7e-12 Prudent dietary pattern; LIHC cis rs11779988 0.543 rs410445 chr8:17882304 C/T cg01800426 chr8:17659068 MTUS1 -0.43 -6.32 -0.32 7.98e-10 Breast cancer; LIHC cis rs6701037 0.967 rs1057302 chr1:175126423 A/G cg17845761 chr1:175162550 KIAA0040 -0.36 -5.85 -0.3 1.15e-8 Alcohol dependence; LIHC cis rs875971 0.628 rs6974355 chr7:65841981 A/G cg18876405 chr7:65276391 NA 0.46 7.54 0.38 4.31e-13 Aortic root size; LIHC cis rs4900538 0.855 rs12590993 chr14:102844064 A/G cg18135206 chr14:102964638 TECPR2 -0.71 -11.11 -0.51 1.1e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2932538 0.922 rs11102508 chr1:113141175 T/C cg22162597 chr1:113214053 CAPZA1 0.68 10.71 0.5 2.84e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs13191362 0.507 rs2849524 chr6:163127070 C/T cg21926612 chr6:163149169 PACRG;PARK2 -0.53 -6.03 -0.31 4.15e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2204008 0.748 rs11514352 chr12:38246954 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.56e-8 Bladder cancer; LIHC cis rs9733 0.596 rs6587516 chr1:150623221 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs853679 0.517 rs9348796 chr6:28126202 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg18000306 chr6:288505 NA 0.36 6.78 0.34 5.32e-11 Menopause (age at onset); LIHC cis rs7512552 0.839 rs17597088 chr1:150475772 A/G cg15654264 chr1:150340011 RPRD2 0.71 11.53 0.53 3.24e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs4727027 0.933 rs917122 chr7:148848257 T/C cg23583168 chr7:148888333 NA -0.73 -10.52 -0.49 1.36e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs875971 0.862 rs801206 chr7:66021966 C/G cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.28e-34 Aortic root size; LIHC cis rs10883723 0.962 rs11191294 chr10:104225837 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 11.47 0.53 5.44e-26 Allergic disease (asthma, hay fever or eczema); LIHC trans rs35110281 0.807 rs1598206 chr21:45058776 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.56 0.33 2.03e-10 Mean corpuscular volume; LIHC cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg08888203 chr3:10149979 C3orf24 0.55 6.35 0.32 6.76e-10 Alzheimer's disease; LIHC cis rs10751667 0.666 rs11246357 chr11:963980 A/C cg06064525 chr11:970664 AP2A2 -0.55 -14.53 -0.62 1.41e-37 Alzheimer's disease (late onset); LIHC trans rs561341 1.000 rs560132 chr17:30320019 C/T cg20587970 chr11:113659929 NA -1.47 -12.03 -0.55 5.04e-28 Hip circumference adjusted for BMI; LIHC cis rs5769707 0.967 rs2187891 chr22:49994094 C/T cg01652190 chr22:50026171 C22orf34 -0.28 -6.1 -0.31 2.89e-9 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6088813 0.925 rs4353719 chr20:33977349 G/A cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC trans rs7618501 1.000 rs35261599 chr3:49773236 G/A cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs3008870 0.755 rs1121824 chr1:67475616 C/A cg08660285 chr1:67390436 MIER1;WDR78 0.64 10.76 0.5 1.86e-23 Lymphocyte percentage of white cells; LIHC cis rs4969178 0.965 rs8077859 chr17:76386335 C/T cg20026190 chr17:76395443 PGS1 0.47 7.36 0.37 1.35e-12 HDL cholesterol levels; LIHC cis rs7666738 0.546 rs28444809 chr4:98916934 C/T cg05340658 chr4:99064831 C4orf37 0.47 6.18 0.32 1.78e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs6952808 0.825 rs34296663 chr7:1935245 C/T cg04565464 chr8:145669602 NFKBIL2 0.39 6.09 0.31 3.01e-9 Bipolar disorder and schizophrenia; LIHC cis rs17826219 0.568 rs11658027 chr17:29094882 A/G cg13385521 chr17:29058706 SUZ12P -0.83 -8.11 -0.4 9.15e-15 Body mass index; LIHC cis rs1801251 1.000 rs6746294 chr2:233583050 C/G cg25237894 chr2:233734115 C2orf82 -0.55 -10.16 -0.48 2.28e-21 Coronary artery disease; LIHC cis rs74181299 0.648 rs1050676 chr2:65310831 A/T cg05010058 chr2:65284262 CEP68 -0.4 -6.66 -0.34 1.13e-10 Pulse pressure; LIHC cis rs4924590 0.531 rs2114477 chr15:42227441 C/T cg20935245 chr15:42234343 EHD4 -0.4 -7.22 -0.36 3.4e-12 Lymphocyte percentage of white cells;Sum basophil neutrophil counts;Granulocyte count; LIHC cis rs7551222 0.749 rs7532236 chr1:204561617 A/G cg20240347 chr1:204465584 NA 0.29 6.19 0.32 1.77e-9 Schizophrenia; LIHC cis rs1865760 0.929 rs1816546 chr6:25938252 C/T cg17691542 chr6:26056736 HIST1H1C 0.4 5.95 0.31 6.61e-9 Height; LIHC cis rs7937682 0.921 rs11213945 chr11:111461003 A/G cg09085632 chr11:111637200 PPP2R1B 0.89 10.17 0.48 2.12e-21 Primary sclerosing cholangitis; LIHC cis rs12477438 0.798 rs6740035 chr2:99576578 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.07 -14.82 -0.63 1.03e-38 Chronic sinus infection; LIHC cis rs7520050 0.778 rs3013597 chr1:46128356 C/A cg03146154 chr1:46216737 IPP 0.5 8.54 0.42 4.4e-16 Red blood cell count;Reticulocyte count; LIHC cis rs7106204 0.514 rs1596280 chr11:24250853 T/C ch.11.24196551F chr11:24239977 NA 0.83 11.91 0.54 1.39e-27 Response to Homoharringtonine (cytotoxicity); LIHC cis rs7918232 0.941 rs4749228 chr10:27433618 C/T cg14240646 chr10:27532245 ACBD5 0.69 6.4 0.33 5.27e-10 Breast cancer; LIHC trans rs4942242 0.663 rs7332737 chr13:44215043 C/T cg19169023 chr15:41853346 TYRO3 -0.51 -7.24 -0.36 3.03e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs739401 0.572 rs410820 chr11:3080102 G/A cg08508325 chr11:3079039 CARS -0.36 -7.64 -0.38 2.15e-13 Longevity; LIHC cis rs1499614 0.803 rs1922723 chr7:66175063 C/T cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC trans rs6934970 1.000 rs6933881 chr6:113123860 A/G cg02462569 chr6:150064036 NUP43 -0.46 -6.09 -0.31 3.1e-9 Bipolar disorder (body mass index interaction); LIHC cis rs4243830 0.737 rs11122083 chr1:6593532 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.9 -10.41 -0.49 3.06e-22 Body mass index; LIHC cis rs9300255 0.602 rs10744147 chr12:123643729 A/G cg00376283 chr12:123451042 ABCB9 0.65 7.04 0.36 1.06e-11 Neutrophil percentage of white cells; LIHC cis rs6963495 0.556 rs711427 chr7:105161755 T/G cg19920283 chr7:105172520 RINT1 0.47 5.98 0.31 5.72e-9 Bipolar disorder (body mass index interaction); LIHC cis rs941873 0.772 rs7920127 chr10:81122914 T/C cg09469691 chr10:81107165 PPIF 0.68 10.21 0.48 1.49e-21 Height; LIHC cis rs10454142 0.845 rs56391806 chr2:48631977 C/T cg15846641 chr2:48541264 FOXN2 0.5 6.53 0.33 2.41e-10 Sex hormone-binding globulin levels; LIHC cis rs7613875 0.580 rs3774745 chr3:50204745 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.5 -7.41 -0.37 9.89e-13 Body mass index; LIHC cis rs7119038 0.774 rs73005426 chr11:118681083 A/G cg19308663 chr11:118741387 NA 0.39 6.04 0.31 4.11e-9 Sjögren's syndrome; LIHC trans rs61931739 0.517 rs1843737 chr12:34015305 A/G cg26384229 chr12:38710491 ALG10B 0.47 6.6 0.34 1.54e-10 Morning vs. evening chronotype; LIHC cis rs4919087 0.561 rs7101333 chr10:99083669 A/G cg25902810 chr10:99078978 FRAT1 -0.59 -6.88 -0.35 2.82e-11 Monocyte count; LIHC cis rs3824867 0.920 rs7107853 chr11:47453518 T/C cg20307385 chr11:47447363 PSMC3 -0.58 -7.96 -0.4 2.62e-14 Mean corpuscular hemoglobin; LIHC cis rs11122272 0.766 rs2790871 chr1:231543555 G/C cg06096015 chr1:231504339 EGLN1 0.49 9.17 0.44 4.42e-18 Hemoglobin concentration; LIHC cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg06634786 chr22:41940651 POLR3H -0.79 -8.69 -0.43 1.58e-16 Vitiligo; LIHC cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg08392591 chr16:89556376 ANKRD11 0.58 9.23 0.45 2.81e-18 Multiple myeloma (IgH translocation); LIHC cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg12463550 chr7:65579703 CRCP 0.67 7.02 0.36 1.17e-11 Diabetic kidney disease; LIHC cis rs12134245 0.776 rs12122066 chr1:92005140 C/T cg07090678 chr1:91966139 CDC7 0.5 6.78 0.34 5.44e-11 Breast cancer; LIHC cis rs367615 0.840 rs113540823 chr5:108879084 C/T cg17395555 chr5:108820864 NA 0.34 7.04 0.36 1.07e-11 Colorectal cancer (SNP x SNP interaction); LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg22903471 chr2:27725779 GCKR -0.48 -8.39 -0.41 1.28e-15 Total body bone mineral density; LIHC cis rs7131987 0.621 rs11050181 chr12:29467669 C/T cg14222432 chr12:29376421 FAR2 0.36 6.84 0.35 3.63e-11 QT interval; LIHC cis rs2404602 0.735 rs12903874 chr15:76693318 A/T cg03037974 chr15:76606532 NA -0.65 -11.6 -0.53 1.8e-26 Blood metabolite levels; LIHC cis rs9948 0.786 rs62156227 chr2:97417942 C/A cg01990225 chr2:97406019 LMAN2L -0.72 -6.23 -0.32 1.37e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs6545883 0.826 rs777590 chr2:61417145 C/G cg14146966 chr2:61757674 XPO1 0.41 6.83 0.35 3.8e-11 Tuberculosis; LIHC cis rs6089584 0.888 rs6061979 chr20:60617141 C/G cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs8060686 0.641 rs76419201 chr16:68153553 G/A cg05110241 chr16:68378359 PRMT7 -0.6 -6.81 -0.35 4.44e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs2637030 0.559 rs256110 chr5:52879803 A/G cg06476337 chr5:52856530 NDUFS4 0.42 6.59 0.34 1.7e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs10733682 0.659 rs867560 chr9:129465233 C/G cg00232160 chr9:129468157 NA -0.34 -5.93 -0.31 7.28e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs17401966 1.000 rs12734068 chr1:10376803 G/A cg19773385 chr1:10388646 KIF1B -0.47 -8.17 -0.4 6.11e-15 Hepatocellular carcinoma; LIHC cis rs2404602 0.647 rs11072616 chr15:76985269 T/C cg23625390 chr15:77176239 SCAPER -0.56 -9.72 -0.47 6.94e-20 Blood metabolite levels; LIHC cis rs1023500 0.505 rs2143139 chr22:42614401 G/C cg00645731 chr22:42541494 CYP2D7P1 0.33 5.72 0.3 2.33e-8 Schizophrenia; LIHC cis rs933688 1.000 rs6862125 chr5:90724598 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.94 18.21 0.7 2.91e-52 Smoking behavior; LIHC cis rs631288 0.793 rs11239952 chr1:146715204 A/G cg25205988 chr1:146714368 CHD1L 0.81 8.27 0.41 3.05e-15 PR interval in Tripanosoma cruzi seropositivity; LIHC cis rs12579753 1.000 rs7966755 chr12:82221604 A/G cg07988820 chr12:82153109 PPFIA2 -0.48 -5.84 -0.3 1.23e-8 Resting heart rate; LIHC cis rs151997 0.962 rs27268 chr5:50184778 T/C cg06027927 chr5:50259733 NA 0.56 7.61 0.38 2.71e-13 Callous-unemotional behaviour; LIHC cis rs798766 0.909 rs11724531 chr4:1753424 A/G cg21231739 chr4:1642635 FAM53A -0.37 -5.93 -0.31 7.49e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg14004847 chr7:1930337 MAD1L1 -0.45 -6.64 -0.34 1.22e-10 Bipolar disorder and schizophrenia; LIHC cis rs4819052 1.000 rs4818769 chr21:46667451 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 9.86 0.47 2.37e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7212590 0.655 rs8067568 chr17:57999215 A/G cg10252138 chr17:58120427 NA -0.6 -6.15 -0.32 2.15e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC trans rs116095464 0.558 rs6866776 chr5:264495 C/T cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07963361 chr7:87505792 SLC25A40;DBF4 0.47 6.41 0.33 4.78e-10 Lung function (FEV1/FVC); LIHC cis rs8084351 0.599 rs12967441 chr18:50675912 G/A cg24270629 chr18:50823537 DCC -0.45 -6.66 -0.34 1.1e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs8141529 0.748 rs9620841 chr22:29290981 C/T cg02153584 chr22:29168773 CCDC117 0.51 7.97 0.4 2.36e-14 Lymphocyte counts; LIHC cis rs8078723 0.510 rs11655264 chr17:38138995 G/C cg17344932 chr17:38183730 MED24;SNORD124 0.71 13.22 0.58 1.59e-32 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22446331 chr18:19750865 GATA6 0.46 6.82 0.35 4.05e-11 Pancreatic cancer; LIHC cis rs1538970 0.816 rs868351 chr1:46009818 G/T cg05343316 chr1:45956843 TESK2 0.61 8.4 0.41 1.17e-15 Platelet count; LIHC trans rs2270927 0.510 rs6891108 chr5:75579152 C/A cg13563193 chr19:33072644 PDCD5 0.99 9.64 0.46 1.26e-19 Mean corpuscular volume; LIHC cis rs7071206 0.853 rs57420220 chr10:79428886 C/T cg07817648 chr10:79422355 NA -0.32 -6.54 -0.33 2.29e-10 Bone mineral density; LIHC cis rs7927771 1.000 rs4752873 chr11:47857520 C/T cg20135002 chr11:47629003 NA -0.54 -9.15 -0.44 5.35e-18 Subjective well-being; LIHC cis rs28595532 0.623 rs34082100 chr4:119220563 C/T cg21605333 chr4:119757512 SEC24D 0.81 6.75 0.34 6.35e-11 Cannabis dependence symptom count; LIHC cis rs2839186 0.706 rs2839188 chr21:47692798 C/T cg11766577 chr21:47581405 C21orf56 -0.39 -5.9 -0.3 8.59e-9 Testicular germ cell tumor; LIHC cis rs9896933 0.887 rs78483419 chr17:80870884 T/C cg20578329 chr17:80767326 TBCD -0.63 -6.01 -0.31 4.82e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs796364 0.755 rs6739563 chr2:201134216 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.77 8.61 0.42 2.74e-16 Schizophrenia; LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.46 0.46 5.21e-19 Height; LIHC trans rs11098499 0.913 rs13126596 chr4:120140729 A/G cg25214090 chr10:38739885 LOC399744 0.45 7.32 0.37 1.84e-12 Corneal astigmatism; LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg19318889 chr4:1322082 MAEA 0.52 8.69 0.43 1.57e-16 Obesity-related traits; LIHC cis rs4862750 0.914 rs11945845 chr4:187874136 T/C cg11301795 chr4:187892539 NA -0.28 -7.37 -0.37 1.27e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.71 0.34 8.07e-11 Bipolar disorder; LIHC cis rs875971 0.895 rs7788984 chr7:65915616 A/G cg11764359 chr7:65958608 NA 0.89 16.15 0.66 5.35e-44 Aortic root size; LIHC cis rs739401 0.527 rs423236 chr11:3065916 C/T cg20651018 chr11:3035856 CARS -0.35 -5.76 -0.3 1.88e-8 Longevity; LIHC cis rs6835098 1.000 rs10027708 chr4:174083116 T/C cg27433088 chr4:174089019 GALNT7 0.38 6.93 0.35 2.07e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg24693881 chr1:107596107 NA 0.52 9.23 0.45 2.85e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs55702914 0.809 rs6738721 chr2:198182334 A/G cg10820045 chr2:198174542 NA -0.41 -6.05 -0.31 3.79e-9 Major depression and alcohol dependence; LIHC cis rs13118159 0.872 rs4974604 chr4:1345798 T/C cg13395646 chr4:1353034 KIAA1530 -0.67 -9.18 -0.44 4.08e-18 Longevity; LIHC cis rs807029 0.533 rs3824783 chr10:102750851 C/T cg25179470 chr10:102756915 LZTS2 0.43 6.07 0.31 3.36e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs713477 1.000 rs28604440 chr14:55911324 C/T cg13175173 chr14:55914753 NA -0.33 -7.52 -0.38 4.76e-13 Pediatric bone mineral content (femoral neck); LIHC cis rs2153535 0.607 rs9502722 chr6:8541483 C/T cg07606381 chr6:8435919 SLC35B3 0.78 11.22 0.52 4.23e-25 Motion sickness; LIHC cis rs13161895 0.702 rs12652904 chr5:179496422 C/T cg02702477 chr5:179499311 RNF130 1.01 13.24 0.58 1.43e-32 LDL cholesterol; LIHC cis rs5753618 0.509 rs2413033 chr22:31574213 A/G cg22777020 chr22:31556080 RNF185 -0.56 -6.35 -0.32 6.93e-10 Colorectal cancer; LIHC cis rs11958404 0.546 rs6556332 chr5:157433684 A/G cg05962755 chr5:157440814 NA 0.61 7.9 0.39 3.75e-14 IgG glycosylation; LIHC cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.26 -0.61 1.61e-36 Alzheimer's disease; LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.61 0.38 2.7e-13 Prudent dietary pattern; LIHC cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.01 -0.44 1.43e-17 Bipolar disorder; LIHC cis rs2204008 0.594 rs11531211 chr12:37998007 T/G cg26384229 chr12:38710491 ALG10B -0.48 -6.74 -0.34 6.91e-11 Bladder cancer; LIHC cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg00750074 chr16:89608354 SPG7 -0.53 -8.67 -0.42 1.76e-16 Multiple myeloma (IgH translocation); LIHC cis rs2180341 1.000 rs2326567 chr6:127606160 G/A cg24812749 chr6:127587940 RNF146 1.06 15.96 0.65 2.91e-43 Breast cancer; LIHC cis rs8016982 0.609 rs8009519 chr14:81702503 C/G cg01989461 chr14:81687754 GTF2A1 0.71 14.64 0.62 5.01e-38 Schizophrenia; LIHC cis rs950173 1.000 rs6716901 chr2:172673453 C/T cg13550731 chr2:172543902 DYNC1I2 -0.59 -6.6 -0.34 1.6e-10 Hippocampal volume; LIHC cis rs600806 0.815 rs10858089 chr1:109926828 T/C cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.931 rs4934711 chr10:35360310 G/A cg03585969 chr10:35415529 CREM 0.85 12.81 0.57 5.76e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12220238 0.841 rs7919010 chr10:76111137 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.27 0.32 1.07e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2191566 1.000 rs369106 chr19:44506930 C/T cg20607764 chr19:44506953 ZNF230 0.44 7.09 0.36 7.7e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg19539972 chr4:7069911 GRPEL1 0.67 9.74 0.47 6.14e-20 Monocyte percentage of white cells; LIHC cis rs7224737 1.000 rs2240010 chr17:40278081 T/A cg02450064 chr17:40260053 DHX58 -0.29 -6.07 -0.31 3.49e-9 Fibrinogen levels; LIHC cis rs67478160 0.643 rs12880821 chr14:104276049 C/T cg01849466 chr14:104193079 ZFYVE21 -0.44 -6.83 -0.35 3.85e-11 Schizophrenia; LIHC cis rs7412746 0.658 rs59024312 chr1:150909005 T/G cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs2404602 0.684 rs1603860 chr15:76849591 A/T cg23625390 chr15:77176239 SCAPER -0.54 -8.96 -0.44 2.11e-17 Blood metabolite levels; LIHC cis rs79387448 0.745 rs7593444 chr2:103158561 G/A cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs7312774 0.618 rs10861680 chr12:107323730 T/C cg16260113 chr12:107380972 MTERFD3 0.85 10.95 0.51 3.98e-24 Severe influenza A (H1N1) infection; LIHC cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.7 0.57 1.5e-30 Total body bone mineral density; LIHC cis rs35110281 0.594 rs230641 chr21:44915441 T/C cg04455712 chr21:45112962 RRP1B -0.39 -6.7 -0.34 8.6e-11 Mean corpuscular volume; LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.1 -0.31 2.94e-9 Total body bone mineral density; LIHC cis rs1200821 0.559 rs9418267 chr10:37819951 A/G cg00409905 chr10:38381863 ZNF37A 0.47 7.56 0.38 3.71e-13 Hemostatic factors and hematological phenotypes; LIHC cis rs7552404 1.000 rs11161521 chr1:76216330 T/C cg10523679 chr1:76189770 ACADM 0.63 8.59 0.42 3.11e-16 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs11098499 0.644 rs28787668 chr4:120554687 G/A cg25214090 chr10:38739885 LOC399744 0.5 8.08 0.4 1.12e-14 Corneal astigmatism; LIHC cis rs1873147 0.569 rs12593573 chr15:63309919 G/A cg05771511 chr15:63340396 TPM1 -0.44 -5.94 -0.31 7.01e-9 Orofacial clefts; LIHC cis rs11662586 0.517 rs11663082 chr18:77713494 C/T cg20368463 chr18:77673604 PQLC1 0.51 8.44 0.42 9.03e-16 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs2070488 0.932 rs4678604 chr3:38444273 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.68 0.65 4.03e-42 Electrocardiographic conduction measures; LIHC cis rs62012628 0.527 rs12438008 chr15:79084680 C/T cg00639195 chr15:79103007 ADAMTS7 0.5 7.47 0.37 6.91e-13 Diastolic blood pressure; LIHC cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg02951883 chr7:2050386 MAD1L1 -0.52 -7.72 -0.39 1.26e-13 Bipolar disorder and schizophrenia; LIHC trans rs11098499 0.645 rs72676059 chr4:120290828 C/G cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.54 0.53 2.97e-26 Prudent dietary pattern; LIHC cis rs2380220 0.541 rs72928277 chr6:96079745 G/T cg04719120 chr6:96025338 MANEA -0.71 -8.44 -0.42 9.36e-16 Behavioural disinhibition (generation interaction); LIHC cis rs4629710 0.592 rs13195700 chr6:131585299 C/T cg12606694 chr6:131520996 AKAP7 0.63 7.34 0.37 1.59e-12 Multiple myeloma (IgH translocation); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg06387028 chr7:72395397 POM121 0.47 6.18 0.32 1.78e-9 Hepatitis; LIHC cis rs7072216 0.763 rs10732782 chr10:100166506 C/A cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC cis rs67981189 0.593 rs4147077 chr14:71454870 A/G cg15816911 chr14:71606274 NA 0.42 6.7 0.34 8.37e-11 Schizophrenia; LIHC trans rs875971 0.545 rs1796217 chr7:66085918 A/G cg26939375 chr7:64535504 NA -0.39 -6.25 -0.32 1.22e-9 Aortic root size; LIHC cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg15691649 chr6:25882328 NA -0.51 -7.33 -0.37 1.65e-12 Blood metabolite levels; LIHC cis rs7572733 0.536 rs6732517 chr2:198912902 G/C cg00792783 chr2:198669748 PLCL1 0.4 5.85 0.3 1.13e-8 Dermatomyositis; LIHC cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.8 -0.57 6.21e-31 Alzheimer's disease; LIHC cis rs6430585 0.583 rs78364332 chr2:136640101 T/C cg15123519 chr2:136567270 LCT -0.37 -6.08 -0.31 3.25e-9 Corneal structure; LIHC cis rs6964587 0.869 rs6979024 chr7:91481512 T/C cg17063962 chr7:91808500 NA -0.98 -18.35 -0.7 7.7e-53 Breast cancer; LIHC cis rs3008870 0.755 rs2755251 chr1:67496425 G/T cg02640540 chr1:67518911 SLC35D1 0.43 6.81 0.35 4.37e-11 Lymphocyte percentage of white cells; LIHC cis rs7552404 1.000 rs7524467 chr1:76194054 C/G cg03433033 chr1:76189801 ACADM 0.64 8.93 0.43 2.76e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2439831 0.681 rs2278859 chr15:43632960 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 16.92 0.67 4.41e-47 Lung cancer in ever smokers; LIHC cis rs16828019 0.929 rs35883594 chr1:41744093 A/G cg03387723 chr1:41708464 SCMH1 -0.43 -6.82 -0.35 4.04e-11 Intelligence (multi-trait analysis); LIHC cis rs4555082 0.957 rs10140586 chr14:105749582 A/G cg13114125 chr14:105738426 BRF1 -0.69 -9.33 -0.45 1.33e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg07677032 chr17:61819896 STRADA 0.42 6.09 0.31 2.96e-9 Prudent dietary pattern; LIHC cis rs4561483 0.673 rs28279 chr16:11968555 A/C cg08843971 chr16:11963173 GSPT1 0.41 8.12 0.4 8.56e-15 Testicular germ cell tumor; LIHC cis rs6545883 0.929 rs1186707 chr2:61673520 C/A cg15711740 chr2:61764176 XPO1 -0.43 -6.01 -0.31 4.66e-9 Tuberculosis; LIHC cis rs12477438 0.520 rs6708576 chr2:99801308 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.38 0.59 3.92e-33 Chronic sinus infection; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25116269 chr2:55509523 PRDXDD1P 0.57 7.3 0.37 2.05e-12 Lung function (FEV1/FVC); LIHC cis rs7666738 0.791 rs28579101 chr4:98843203 T/C cg05340658 chr4:99064831 C4orf37 0.64 11.67 0.53 1.07e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg00280220 chr17:61926910 NA 0.43 6.83 0.35 3.87e-11 Prudent dietary pattern; LIHC cis rs1059312 1.000 rs7135854 chr12:129279988 G/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.73 -14.43 -0.62 3.3e-37 Systemic lupus erythematosus; LIHC cis rs12824058 0.549 rs4759453 chr12:130824565 C/G cg24838063 chr12:130822603 PIWIL1 0.67 9.86 0.47 2.43e-20 Menopause (age at onset); LIHC cis rs3015497 0.711 rs4343181 chr14:51162848 C/T cg09863266 chr14:51125203 SAV1 -0.38 -5.93 -0.31 7.29e-9 Mean platelet volume; LIHC cis rs5770917 1.000 rs762677 chr22:51017713 G/A cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.48 -5.92 -0.3 7.89e-9 Narcolepsy; LIHC cis rs80282103 0.618 rs11250252 chr10:1124939 G/C cg18964960 chr10:1102726 WDR37 0.66 5.9 0.3 8.54e-9 Glomerular filtration rate (creatinine); LIHC cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -9.49 -0.46 3.97e-19 Platelet count; LIHC cis rs9303401 0.612 rs2526370 chr17:56487636 G/C cg25039879 chr17:56429692 SUPT4H1 0.42 5.93 0.31 7.56e-9 Cognitive test performance; LIHC cis rs1712517 0.771 rs10883858 chr10:105127708 G/A cg05636881 chr10:105038444 INA 0.48 7.54 0.38 4.29e-13 Migraine; LIHC cis rs12980942 1.000 rs8109167 chr19:41823167 G/T cg25627403 chr19:41769009 HNRNPUL1 0.47 5.91 0.3 8.07e-9 Coronary artery disease; LIHC cis rs4638749 0.677 rs13423385 chr2:108826435 C/G cg06795125 chr2:108905320 SULT1C2 -0.3 -6.12 -0.31 2.52e-9 Blood pressure; LIHC cis rs8180040 0.966 rs9683033 chr3:47489820 C/T cg16586182 chr3:47516702 SCAP -0.57 -11.05 -0.51 1.77e-24 Colorectal cancer; LIHC cis rs10464366 0.544 rs6952466 chr7:39155032 A/T cg10621924 chr7:39171070 POU6F2 0.42 6.66 0.34 1.1e-10 IgG glycosylation; LIHC cis rs5769765 0.908 rs138889 chr22:50226673 T/C cg26441486 chr22:50317300 CRELD2 0.35 5.93 0.31 7.4e-9 Schizophrenia; LIHC cis rs9948 0.655 rs62156216 chr2:97405127 C/T cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1059312 1.000 rs2291350 chr12:129283711 G/A cg09035930 chr12:129282057 SLC15A4 0.68 13.04 0.58 8.05e-32 Systemic lupus erythematosus; LIHC cis rs3099143 1.000 rs4541044 chr15:77173193 C/T cg21673338 chr15:77095150 SCAPER 0.51 7.94 0.39 2.93e-14 Recalcitrant atopic dermatitis; LIHC cis rs7191439 0.858 rs8050715 chr16:88780923 C/G cg27087555 chr16:88793112 FAM38A -1.32 -12.51 -0.56 8.09e-30 Plateletcrit; LIHC cis rs7224685 0.569 rs10521129 chr17:4008820 C/T cg11204139 chr17:3907470 NA 0.6 7.38 0.37 1.21e-12 Type 2 diabetes; LIHC cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg03264133 chr6:25882463 NA -0.59 -8.43 -0.41 9.93e-16 Blood metabolite levels; LIHC cis rs929354 0.772 rs10229630 chr7:157004790 C/T cg05182265 chr7:156933206 UBE3C -0.31 -5.91 -0.3 8.44e-9 Body mass index; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg09417038 chr21:47716443 C21orf57 0.52 7.94 0.39 2.93e-14 Testicular germ cell tumor; LIHC cis rs35306767 0.714 rs17293608 chr10:1056252 C/T cg20503657 chr10:835505 NA 0.8 7.86 0.39 5.22e-14 Eosinophil percentage of granulocytes; LIHC cis rs9788682 0.748 rs2456020 chr15:78868398 C/T cg06917634 chr15:78832804 PSMA4 -0.44 -5.91 -0.3 8.24e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs7674212 0.541 rs2045746 chr4:104083578 A/C cg16532752 chr4:104119610 CENPE 0.4 6.34 0.32 7.33e-10 Type 2 diabetes; LIHC cis rs6088580 0.634 rs2378134 chr20:32938085 C/T cg08999081 chr20:33150536 PIGU -0.66 -13.1 -0.58 4.7e-32 Glomerular filtration rate (creatinine); LIHC cis rs7818688 0.697 rs112076731 chr8:95978121 C/G cg16049864 chr8:95962084 TP53INP1 0.62 6.77 0.34 5.7e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs3768617 0.706 rs8179460 chr1:183056222 T/C ch.1.3577855R chr1:183094577 LAMC1 0.52 8.31 0.41 2.26e-15 Fuchs's corneal dystrophy; LIHC cis rs80282103 0.764 rs10047383 chr10:1103095 A/G cg18964960 chr10:1102726 WDR37 0.7 6.6 0.34 1.52e-10 Glomerular filtration rate (creatinine); LIHC cis rs1707322 0.721 rs10890343 chr1:46157922 C/T cg06784218 chr1:46089804 CCDC17 0.4 7.43 0.37 8.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17401966 0.931 rs12137880 chr1:10388620 T/C cg15208524 chr1:10270712 KIF1B 0.41 6.24 0.32 1.32e-9 Hepatocellular carcinoma; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg24846343 chr22:24311635 DDTL 0.59 10.9 0.51 5.86e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9303280 0.618 rs4065986 chr17:38102641 G/A cg17467752 chr17:38218738 THRA 0.39 6.36 0.33 6.28e-10 Self-reported allergy; LIHC cis rs12497850 0.931 rs6446253 chr3:48911443 C/T cg07636037 chr3:49044803 WDR6 0.92 16.56 0.67 1.24e-45 Parkinson's disease; LIHC cis rs17685 0.672 rs1639618 chr7:75701987 T/C cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg25072359 chr17:41440525 NA 0.38 5.97 0.31 5.92e-9 Menopause (age at onset); LIHC cis rs2933343 0.601 rs1680759 chr3:128594896 C/G cg24203234 chr3:128598194 ACAD9 0.44 6.18 0.32 1.78e-9 IgG glycosylation; LIHC cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.65 0.38 2e-13 Electroencephalogram traits; LIHC cis rs7927592 0.956 rs10896337 chr11:68284236 T/C cg16797656 chr11:68205561 LRP5 0.53 8.39 0.41 1.31e-15 Total body bone mineral density; LIHC cis rs2370759 1.000 rs11599044 chr10:32615445 A/G cg18270830 chr10:32634957 EPC1 0.53 6.6 0.34 1.61e-10 Sexual dysfunction (female); LIHC cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg13397359 chr6:42928475 GNMT 0.64 9.35 0.45 1.16e-18 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9393777 0.513 rs13195210 chr6:26646521 C/T cg12826209 chr6:26865740 GUSBL1 0.57 5.92 0.3 8.01e-9 Intelligence (multi-trait analysis); LIHC cis rs2274273 1.000 rs3742566 chr14:55595839 T/A cg01864836 chr14:55583639 NA -0.36 -6.13 -0.31 2.43e-9 Protein biomarker; LIHC cis rs1664789 0.904 rs1694063 chr5:53279558 G/A ch.5.1024479R chr5:53302184 ARL15 0.54 8.39 0.41 1.31e-15 Waist circumference adjusted for body mass index; LIHC cis rs6750047 0.756 rs336038 chr2:38260750 C/G cg07380506 chr2:38303506 CYP1B1 0.5 6.1 0.31 2.9e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs17376456 0.877 rs10476597 chr5:93367172 C/T cg25358565 chr5:93447407 FAM172A -1.09 -10.22 -0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs1707322 0.655 rs3014240 chr1:46089225 C/G cg06784218 chr1:46089804 CCDC17 -0.43 -7.78 -0.39 8.65e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs77633900 0.772 rs77582696 chr15:76669153 A/G cg21673338 chr15:77095150 SCAPER -0.51 -5.78 -0.3 1.73e-8 Non-glioblastoma glioma;Glioma; LIHC cis rs801193 1.000 rs62466793 chr7:66191517 G/A cg18876405 chr7:65276391 NA 0.42 7.29 0.37 2.17e-12 Aortic root size; LIHC cis rs7833790 1.000 rs7833790 chr8:82731157 T/C cg27398817 chr8:82754497 SNX16 -0.4 -7.11 -0.36 6.7e-12 Diastolic blood pressure; LIHC cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs3096299 0.967 rs2965827 chr16:89457350 A/C cg08392591 chr16:89556376 ANKRD11 -0.39 -6.02 -0.31 4.41e-9 Multiple myeloma (IgH translocation); LIHC cis rs34779708 0.931 rs12776390 chr10:35391535 T/G cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.59e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs8062405 0.723 rs4788077 chr16:28569764 G/C cg07382826 chr16:28625726 SULT1A1 0.49 7.5 0.38 5.61e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7772486 0.790 rs9403756 chr6:146257761 C/G cg05347473 chr6:146136440 FBXO30 -0.38 -5.89 -0.3 9.23e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8077889 0.826 rs60085355 chr17:41847415 T/C cg26893861 chr17:41843967 DUSP3 0.88 9.85 0.47 2.52e-20 Triglycerides; LIHC cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg11764359 chr7:65958608 NA 0.61 6.37 0.33 6.21e-10 Diabetic kidney disease; LIHC cis rs763121 0.853 rs2267393 chr22:39101619 G/C cg06022373 chr22:39101656 GTPBP1 0.74 14.71 0.62 2.82e-38 Menopause (age at onset); LIHC cis rs2806561 0.765 rs2806557 chr1:23503372 T/A cg12483005 chr1:23474871 LUZP1 0.47 7.47 0.37 6.85e-13 Height; LIHC cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg05555928 chr11:63887634 MACROD1 0.56 7.54 0.38 4.22e-13 Mean platelet volume; LIHC cis rs12479064 0.724 rs6748200 chr2:100080895 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.68 -8.4 -0.41 1.22e-15 Chronic sinus infection; LIHC trans rs1814175 0.645 rs28478790 chr11:50054322 C/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs2637266 1.000 rs10824429 chr10:78346196 G/T cg18941641 chr10:78392320 NA 0.3 6.36 0.33 6.4e-10 Pulmonary function; LIHC cis rs763121 0.853 rs6001175 chr22:39018334 T/C cg14440974 chr22:39074834 NA -0.36 -6.03 -0.31 4.15e-9 Menopause (age at onset); LIHC cis rs249954 0.512 rs34514 chr16:23670597 G/A cg05131483 chr16:23706242 ERN2 0.38 6.3 0.32 8.91e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4660261 0.526 rs3011228 chr1:44325995 A/G cg12908607 chr1:44402522 ARTN -0.47 -7.83 -0.39 6.05e-14 Intelligence (multi-trait analysis); LIHC cis rs7769051 1.000 rs7761365 chr6:133101561 T/A cg22852734 chr6:133119734 C6orf192 0.94 9.28 0.45 1.95e-18 Type 2 diabetes nephropathy; LIHC cis rs4727027 0.704 rs2888600 chr7:148908562 C/T cg23583168 chr7:148888333 NA -0.69 -10.88 -0.51 7.35e-24 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs11122272 0.766 rs2739511 chr1:231526490 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.93 -0.51 4.89e-24 Hemoglobin concentration; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg10755058 chr3:40428713 ENTPD3 0.4 6.69 0.34 8.89e-11 Renal cell carcinoma; LIHC cis rs10751667 0.925 rs7115336 chr11:988101 C/G cg10932868 chr11:921992 NA 0.34 6.32 0.32 8.22e-10 Alzheimer's disease (late onset); LIHC cis rs3806843 0.712 rs2530244 chr5:140109155 A/G cg19875535 chr5:140030758 IK -0.39 -6.31 -0.32 8.65e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs13040088 1.000 rs12480870 chr20:61543606 A/C cg23096297 chr20:61557774 DIDO1 0.85 11.5 0.53 4.15e-26 Menopause (age at onset); LIHC cis rs2067615 0.524 rs1922436 chr12:107065258 A/G cg15890332 chr12:107067104 RFX4 0.27 6.35 0.32 6.73e-10 Heart rate; LIHC cis rs6546550 0.935 rs4241261 chr2:70063660 A/G cg02498382 chr2:70120550 SNRNP27 -0.38 -6.31 -0.32 8.51e-10 Prevalent atrial fibrillation; LIHC cis rs4665809 1.000 rs6729757 chr2:26285102 A/G cg27170947 chr2:26402098 FAM59B -0.63 -7.79 -0.39 8.3e-14 Gut microbiome composition (summer); LIHC trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg26692224 chr17:62915920 LRRC37A3 -0.68 -6.76 -0.34 5.89e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg10802521 chr3:52805072 NEK4 -0.42 -7.06 -0.36 9.26e-12 Bipolar disorder; LIHC cis rs875971 0.862 rs11984115 chr7:65773859 C/T cg18876405 chr7:65276391 NA -0.35 -6.35 -0.32 6.94e-10 Aortic root size; LIHC cis rs3096299 0.685 rs4785571 chr16:89565169 A/G cg02187348 chr16:89574699 SPG7 0.56 9.28 0.45 1.96e-18 Multiple myeloma (IgH translocation); LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.71 -0.34 7.94e-11 Lymphocyte counts; LIHC cis rs35306767 0.903 rs7074642 chr10:878359 A/G cg20503657 chr10:835505 NA 1.05 12.56 0.56 5.19e-30 Eosinophil percentage of granulocytes; LIHC trans rs3783890 0.832 rs34243429 chr14:93804125 C/T cg02802420 chr16:69363236 PDF;COG8 0.34 6.47 0.33 3.44e-10 Body mass index; LIHC cis rs17213078 0.602 rs4851113 chr2:106747009 G/C cg15412446 chr2:106886593 NA 0.39 5.73 0.3 2.17e-8 Facial morphology (factor 23); LIHC cis rs6456156 0.586 rs1358883 chr6:167467433 C/G cg12798992 chr6:167411361 FGFR1OP -0.41 -6.38 -0.33 5.82e-10 Primary biliary cholangitis; LIHC cis rs911119 0.913 rs67483168 chr20:23581312 T/C cg16589663 chr20:23618590 CST3 0.72 7.24 0.36 2.95e-12 Chronic kidney disease; LIHC cis rs2836950 0.565 rs2836934 chr21:40564885 A/C cg11890956 chr21:40555474 PSMG1 -0.48 -7.89 -0.39 4.16e-14 Menarche (age at onset); LIHC cis rs11676348 0.967 rs4672873 chr2:219005210 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.42 -5.79 -0.3 1.58e-8 Ulcerative colitis; LIHC cis rs208520 0.661 rs207090 chr6:66783963 T/A cg07460842 chr6:66804631 NA -0.84 -9.11 -0.44 7.04e-18 Exhaled nitric oxide output; LIHC cis rs1997103 1.000 rs2331063 chr7:55408914 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2717559 0.561 rs7841267 chr8:143881683 A/C cg07661805 chr8:143867942 LY6D -0.31 -6.68 -0.34 9.41e-11 Urinary tract infection frequency; LIHC cis rs4638749 0.677 rs998186 chr2:108844237 C/T cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs57502260 0.704 rs72936599 chr11:68320405 G/A cg20283391 chr11:68216788 NA -0.52 -6.15 -0.32 2.16e-9 Total body bone mineral density (age 45-60); LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg00187635 chr16:83986795 OSGIN1 0.41 6.04 0.31 4.02e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs921968 0.565 rs7605055 chr2:219627050 G/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.954 rs903717 chr8:58167856 A/G cg02290350 chr8:58132656 NA 0.39 8.87 0.43 4.18e-17 Developmental language disorder (linguistic errors); LIHC cis rs611744 0.934 rs1668178 chr8:109191700 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs67311347 0.869 rs6790495 chr3:40366770 C/T cg24209194 chr3:40518798 ZNF619 0.45 6.34 0.32 7.37e-10 Renal cell carcinoma; LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg11060661 chr22:24314208 DDT;DDTL -0.6 -9.74 -0.47 6.02e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7917772 0.503 rs7914389 chr10:104295402 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.05 0.58 7.17e-32 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7927771 0.864 rs2293577 chr11:47437202 C/T cg20307385 chr11:47447363 PSMC3 0.5 6.57 0.33 1.9e-10 Subjective well-being; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.36 -0.37 1.35e-12 Bipolar disorder; LIHC cis rs72781680 0.821 rs56064672 chr2:24156769 G/T cg08917208 chr2:24149416 ATAD2B 0.64 6.4 0.33 5.15e-10 Lymphocyte counts; LIHC cis rs5417 0.662 rs8067500 chr17:7172631 A/G cg25256661 chr17:7137939 DVL2 0.81 12.87 0.57 3.42e-31 Diastolic blood pressure; LIHC cis rs8062405 0.755 rs4787455 chr16:28589455 G/A cg07382826 chr16:28625726 SULT1A1 0.5 7.74 0.39 1.13e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg14671364 chr1:107599128 PRMT6 -0.54 -7.9 -0.39 3.92e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2742417 0.603 rs2742455 chr3:45767116 A/G cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs6542838 0.702 rs6419564 chr2:99534113 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.2 -0.32 1.58e-9 Fear of minor pain; LIHC cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.95 -10.37 -0.49 4.44e-22 Platelet count; LIHC cis rs1385374 0.920 rs11059911 chr12:129271936 T/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.7 0.38 1.52e-13 Systemic lupus erythematosus; LIHC cis rs763121 0.853 rs5750630 chr22:38985818 A/C cg06022373 chr22:39101656 GTPBP1 0.68 11.91 0.54 1.4e-27 Menopause (age at onset); LIHC cis rs1707322 1.000 rs11211228 chr1:46399840 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.77e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2228479 0.717 rs1800358 chr16:89809319 T/C cg04013166 chr16:89971882 TCF25 0.47 6.02 0.31 4.48e-9 Skin colour saturation; LIHC cis rs875971 0.830 rs4718358 chr7:65973668 T/C cg11764359 chr7:65958608 NA 0.92 17.21 0.68 3.1e-48 Aortic root size; LIHC cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg21522988 chr12:29376872 FAR2 0.29 6.58 0.34 1.77e-10 QT interval; LIHC cis rs10761482 0.500 rs2211220 chr10:62271491 A/G cg00509281 chr10:62554092 CDC2;CDK1 -0.33 -5.85 -0.3 1.17e-8 Schizophrenia; LIHC cis rs7707921 0.914 rs4081859 chr5:81466669 G/A cg15871215 chr5:81402204 ATG10 0.59 5.85 0.3 1.15e-8 Breast cancer; LIHC cis rs11105298 0.891 rs12228177 chr12:89862030 G/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.54 -0.38 4.24e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14304014 chr19:1625356 TCF3 0.43 6.79 0.34 5e-11 Bilirubin levels; LIHC cis rs7208859 0.673 rs9899525 chr17:29120296 T/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4319547 0.506 rs2062488 chr12:122804256 C/T cg23029597 chr12:123009494 RSRC2 0.45 6.41 0.33 4.96e-10 Body mass index; LIHC cis rs28735056 0.591 rs62101204 chr18:77712832 G/A cg20368463 chr18:77673604 PQLC1 0.35 6.08 0.31 3.24e-9 Schizophrenia; LIHC cis rs986417 0.786 rs7156379 chr14:61110634 G/C cg27398547 chr14:60952738 C14orf39 0.65 6.47 0.33 3.43e-10 Gut microbiota (bacterial taxa); LIHC cis rs919433 0.679 rs10931787 chr2:198520615 A/G cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9549367 0.789 rs34989271 chr13:113894766 G/A cg18105134 chr13:113819100 PROZ -0.66 -11.52 -0.53 3.63e-26 Platelet distribution width; LIHC cis rs9790314 0.521 rs13084746 chr3:161086038 G/A cg03342759 chr3:160939853 NMD3 -0.43 -6.25 -0.32 1.23e-9 Morning vs. evening chronotype; LIHC cis rs9325144 0.650 rs6582631 chr12:38744135 T/C cg26384229 chr12:38710491 ALG10B 0.56 7.75 0.39 1.04e-13 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg08219700 chr8:58056026 NA 0.51 6.6 0.34 1.53e-10 Developmental language disorder (linguistic errors); LIHC cis rs7914558 0.932 rs4307650 chr10:104959852 C/A cg15744005 chr10:104629667 AS3MT -0.39 -8.64 -0.42 2.15e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3020736 0.500 rs6002616 chr22:42504679 A/G cg04733989 chr22:42467013 NAGA -0.66 -9.47 -0.46 4.7e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs12477438 1.000 rs12053372 chr2:99810055 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.55 -6.82 -0.35 4.13e-11 Chronic sinus infection; LIHC cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg17554472 chr22:41940697 POLR3H 0.56 6.23 0.32 1.34e-9 Vitiligo; LIHC cis rs1018836 0.923 rs13277387 chr8:91633713 C/G cg16814680 chr8:91681699 NA -0.57 -9.19 -0.44 4.02e-18 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 0.901 rs73142137 chr7:65343442 A/T cg07424592 chr7:64974309 NA 0.81 9.05 0.44 1.13e-17 Diabetic kidney disease; LIHC cis rs17685 0.884 rs8565 chr7:75630274 T/C cg01364799 chr7:75623366 TMEM120A 0.47 7.13 0.36 6.19e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1030877 1.000 rs2241797 chr2:105885961 T/C cg02079111 chr2:105885981 TGFBRAP1 0.68 11.96 0.54 8.99e-28 Obesity-related traits; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.55 7.93 0.39 3.23e-14 Lymphocyte counts; LIHC cis rs1823913 0.927 rs56209234 chr2:192126474 T/C cg12404831 chr2:192114017 MYO1B 0.33 6.69 0.34 9.35e-11 Obesity-related traits; LIHC cis rs11233413 1.000 rs11233405 chr11:82709630 A/G cg24227371 chr11:82718527 RAB30 0.33 7.09 0.36 7.54e-12 Economic and political preferences (feminism/equality); LIHC cis rs3755132 0.929 rs976016 chr2:15772865 A/G cg12888861 chr2:15731646 DDX1 0.39 5.98 0.31 5.65e-9 Wilms tumor; LIHC cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9814567 1.000 rs7433991 chr3:134312292 A/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs116095464 0.558 rs2288458 chr5:231260 C/T cg22857025 chr5:266934 NA -1.48 -18.2 -0.7 3.22e-52 Breast cancer; LIHC cis rs875971 0.929 rs778692 chr7:65872449 A/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs4718428 0.705 rs4718422 chr7:66359269 A/G cg12165864 chr7:66369176 NA -0.47 -6.82 -0.35 4.17e-11 Corneal structure; LIHC cis rs74233809 1.000 rs11191472 chr10:104707016 A/T cg03493300 chr10:104813866 CNNM2 0.46 5.89 0.3 9.22e-9 Birth weight; LIHC cis rs1005277 0.579 rs1780146 chr10:38517874 C/A cg17219203 chr10:38645113 HSD17B7P2 -0.4 -5.83 -0.3 1.26e-8 Extrinsic epigenetic age acceleration; LIHC cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg16423285 chr20:60520624 NA 0.52 8.67 0.42 1.71e-16 Obesity-related traits; LIHC trans rs8113308 0.810 rs55810059 chr19:52450728 G/A cg14959425 chr7:20447707 ITGB8 -0.47 -6.11 -0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20979786 chr7:74072997 GTF2I 0.37 6.06 0.31 3.56e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7107174 1.000 rs11237468 chr11:78072833 A/G cg02023728 chr11:77925099 USP35 0.41 7.9 0.39 3.83e-14 Testicular germ cell tumor; LIHC cis rs8062405 0.755 rs4788073 chr16:28594549 A/G cg00204512 chr16:28754710 NA 0.41 7.29 0.37 2.19e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1008375 1.000 rs2872958 chr4:17665032 A/G cg02297831 chr4:17616191 MED28 0.42 6.63 0.34 1.28e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs921968 0.678 rs500422 chr2:219432995 C/A cg02985541 chr2:219472218 PLCD4 0.44 7.99 0.4 2.04e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs7635838 0.654 rs347585 chr3:11286220 C/T cg00170343 chr3:11313890 ATG7 0.51 7.46 0.37 7.36e-13 HDL cholesterol; LIHC cis rs72627123 0.867 rs75773875 chr14:74498053 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 9.1 0.44 7.55e-18 Morning vs. evening chronotype; LIHC cis rs34172651 0.876 rs1862451 chr16:24803620 A/G cg04756594 chr16:24857601 SLC5A11 0.48 7.42 0.37 9.33e-13 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg24531977 chr5:56204891 C5orf35 0.73 10.2 0.48 1.68e-21 Initial pursuit acceleration; LIHC cis rs875971 1.000 rs778726 chr7:65828731 C/T cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg12516959 chr21:47718080 NA 0.35 5.84 0.3 1.21e-8 Testicular germ cell tumor; LIHC trans rs116095464 0.558 rs12173244 chr5:269524 G/A cg00938859 chr5:1591904 SDHAP3 0.62 7.56 0.38 3.78e-13 Breast cancer; LIHC cis rs9325144 0.555 rs10748433 chr12:38696352 C/G cg26384229 chr12:38710491 ALG10B 0.57 7.86 0.39 4.91e-14 Morning vs. evening chronotype; LIHC cis rs9303401 0.659 rs34878689 chr17:56694330 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.98 12.97 0.57 1.48e-31 Cognitive test performance; LIHC cis rs7027203 0.828 rs10122041 chr9:96615517 A/G cg13679303 chr9:96623674 NA -0.28 -6.28 -0.32 1.06e-9 DNA methylation (variation); LIHC trans rs459571 0.959 rs460888 chr9:136913123 C/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.56 -8.44 -0.42 9.22e-16 Platelet distribution width; LIHC cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg10360323 chr17:41437877 NA 0.39 5.71 0.3 2.44e-8 Menopause (age at onset); LIHC cis rs2274273 0.837 rs7146748 chr14:55747086 G/A cg04306507 chr14:55594613 LGALS3 0.32 5.85 0.3 1.13e-8 Protein biomarker; LIHC cis rs700651 0.757 rs6748683 chr2:198878008 T/A cg10820045 chr2:198174542 NA 0.46 6.8 0.35 4.58e-11 Intracranial aneurysm; LIHC cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.11 0.52 1.04e-24 Platelet count; LIHC cis rs9640161 0.659 rs17837498 chr7:150009679 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -7.99 -0.4 2.14e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs66887589 0.592 rs2175383 chr4:120215836 C/A cg09307838 chr4:120376055 NA 0.55 8.06 0.4 1.3e-14 Diastolic blood pressure; LIHC cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg23758822 chr17:41437982 NA 0.92 17.02 0.68 1.74e-47 Menopause (age at onset); LIHC trans rs2504916 0.830 rs2504934 chr6:160781666 A/G cg15145357 chr6:170893815 PDCD2 -0.53 -6.3 -0.32 9.05e-10 Response to hepatitis C treatment; LIHC cis rs1395 0.848 rs6716850 chr2:27525350 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -5.83 -0.3 1.31e-8 Blood metabolite levels; LIHC cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg05555928 chr11:63887634 MACROD1 0.56 7.56 0.38 3.66e-13 Mean platelet volume; LIHC cis rs7659604 0.540 rs7676867 chr4:122671315 T/C cg19671926 chr4:122722719 EXOSC9 0.49 7.16 0.36 4.87e-12 Type 2 diabetes; LIHC cis rs11758351 1.000 rs111596617 chr6:26191678 A/T cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs11758351 0.660 rs16891455 chr6:26230485 G/A cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs9303401 0.615 rs7502342 chr17:56922629 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.58 0.59 6.99e-34 Cognitive test performance; LIHC cis rs116095464 0.558 rs7703803 chr5:292311 A/G cg22857025 chr5:266934 NA -1.48 -18.04 -0.7 1.35e-51 Breast cancer; LIHC trans rs801193 0.935 rs11772264 chr7:66176387 T/C cg26939375 chr7:64535504 NA 0.42 6.71 0.34 8.32e-11 Aortic root size; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg06873352 chr17:61820015 STRADA 0.72 12.49 0.56 9.37e-30 Prudent dietary pattern; LIHC cis rs17106184 1.000 rs72904726 chr1:51339332 T/C cg07174182 chr1:51127561 FAF1 -0.62 -6.5 -0.33 2.91e-10 Type 2 diabetes; LIHC cis rs11630290 0.736 rs4777370 chr15:64160104 G/A cg12036633 chr15:63758958 NA 0.61 5.84 0.3 1.21e-8 Iris characteristics; LIHC cis rs1215050 0.704 rs783915 chr4:99023151 C/G cg05340658 chr4:99064831 C4orf37 0.39 5.98 0.31 5.7e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs875971 0.862 rs2024192 chr7:66041447 G/T cg18876405 chr7:65276391 NA -0.34 -6.29 -0.32 9.45e-10 Aortic root size; LIHC trans rs1945213 0.694 rs7129022 chr11:55876132 A/G cg03929089 chr4:120376271 NA 0.54 6.86 0.35 3.28e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs7447593 0.626 rs3812036 chr5:176813404 C/T cg05207973 chr5:176823642 SLC34A1 0.34 6.1 0.31 2.89e-9 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs6540556 0.635 rs17389184 chr1:209916789 C/T cg05527609 chr1:210001259 C1orf107 -0.66 -8.52 -0.42 5.08e-16 Red blood cell count; LIHC cis rs10463316 0.894 rs6579860 chr5:150752338 G/A cg03212797 chr5:150827313 SLC36A1 -0.46 -7.07 -0.36 8.77e-12 Metabolite levels (Pyroglutamine); LIHC cis rs61677309 1.000 rs55940627 chr11:118163920 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.58 0.34 1.82e-10 Lung cancer in ever smokers; LIHC cis rs1577917 0.771 rs9353318 chr6:86231721 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 12.32 0.55 3.97e-29 Response to antipsychotic treatment; LIHC cis rs2832191 0.655 rs2247110 chr21:30323888 G/A cg24692254 chr21:30365293 RNF160 -0.85 -14.65 -0.62 4.59e-38 Dental caries; LIHC cis rs743757 1.000 rs2236987 chr3:50504546 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.56 -8.68 -0.42 1.66e-16 Diastolic blood pressure; LIHC cis rs1712517 0.771 rs61871160 chr10:105144288 C/T cg05636881 chr10:105038444 INA 0.5 7.71 0.38 1.36e-13 Migraine; LIHC cis rs12586317 0.547 rs2273154 chr14:35433187 C/T cg16230307 chr14:35515116 FAM177A1 0.77 12.6 0.56 3.53e-30 Psoriasis; LIHC cis rs78545713 0.649 rs113407109 chr6:26224403 T/G cg16070018 chr6:26224392 HIST1H3E 0.8 7.54 0.38 4.2e-13 Iron status biomarkers (total iron binding capacity); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg03056468 chr15:68155977 NA -0.43 -6.15 -0.32 2.13e-9 Alopecia areata; LIHC cis rs10791097 0.667 rs4937584 chr11:130741761 A/G cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs910316 1.000 rs175425 chr14:75626131 T/C cg11812906 chr14:75593930 NEK9 -0.74 -14.17 -0.61 3.62e-36 Height; LIHC cis rs986417 1.000 rs1956875 chr14:60846212 T/C cg27398547 chr14:60952738 C14orf39 -0.76 -8.81 -0.43 6.55e-17 Gut microbiota (bacterial taxa); LIHC cis rs2455799 0.594 rs11128769 chr3:15926230 C/T cg12698662 chr3:15914712 MIR563 -0.37 -7.02 -0.35 1.22e-11 Mean platelet volume; LIHC cis rs35160687 0.644 rs1863056 chr2:86491245 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.35 5.75 0.3 2.01e-8 Night sleep phenotypes; LIHC cis rs875971 1.000 rs6946143 chr7:65579722 A/C cg18876405 chr7:65276391 NA 0.37 6.84 0.35 3.77e-11 Aortic root size; LIHC cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg11645453 chr3:52864694 ITIH4 0.21 5.84 0.3 1.23e-8 Bipolar disorder; LIHC cis rs4555082 0.915 rs28594491 chr14:105758018 G/A cg13114125 chr14:105738426 BRF1 -0.73 -9.53 -0.46 3.04e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg03517284 chr6:25882590 NA -0.6 -7.42 -0.37 9.66e-13 Intelligence (multi-trait analysis); LIHC cis rs986417 0.901 rs12436953 chr14:61001546 C/T cg27398547 chr14:60952738 C14orf39 0.82 9.42 0.45 6.85e-19 Gut microbiota (bacterial taxa); LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs3849570 0.555 rs9968070 chr3:82010368 G/A cg07356753 chr3:81810745 GBE1 -0.42 -6.34 -0.32 7.14e-10 Waist circumference;Body mass index; LIHC cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg19318889 chr4:1322082 MAEA 0.47 6.55 0.33 2.07e-10 Obesity-related traits; LIHC trans rs28735056 0.587 rs8093548 chr18:77636451 G/A cg05926928 chr17:57297772 GDPD1 -0.52 -7.53 -0.38 4.62e-13 Schizophrenia; LIHC cis rs9372253 1.000 rs11153232 chr6:110716252 G/T cg01119278 chr6:110721349 DDO 0.3 6.44 0.33 4.12e-10 Platelet distribution width; LIHC cis rs8060686 0.516 rs1971546 chr16:68280893 T/C cg05110241 chr16:68378359 PRMT7 -0.54 -6.53 -0.33 2.36e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs2559856 0.935 rs2695287 chr12:102088361 T/C cg12924262 chr12:102091054 CHPT1 0.52 8.36 0.41 1.56e-15 Blood protein levels; LIHC cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg08219700 chr8:58056026 NA 0.54 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.773 rs9616208 chr22:50313359 G/A cg09182678 chr22:50328711 NA -0.44 -6.23 -0.32 1.37e-9 Schizophrenia; LIHC cis rs7619427 0.643 rs67261579 chr3:44084328 C/T cg24966902 chr3:44043705 NA 0.51 6.59 0.34 1.68e-10 Schizophrenia; LIHC cis rs4820294 0.669 rs9622678 chr22:38057338 A/G cg00292662 chr22:38071168 LGALS1 0.39 6.65 0.34 1.19e-10 Fat distribution (HIV); LIHC cis rs2404602 0.735 rs2461871 chr15:76822418 C/G cg23625390 chr15:77176239 SCAPER -0.45 -7.39 -0.37 1.14e-12 Blood metabolite levels; LIHC cis rs6933660 0.800 rs9383893 chr6:151757327 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.5 7.39 0.37 1.11e-12 Menarche (age at onset); LIHC cis rs12477438 0.520 rs1133978 chr2:99741964 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC trans rs4718428 0.705 rs28648401 chr7:66367132 T/C cg10756647 chr7:56101905 PSPH 0.64 8.81 0.43 6.36e-17 Corneal structure; LIHC cis rs854765 0.647 rs741782 chr17:18019712 T/C cg04398451 chr17:18023971 MYO15A -0.76 -13.48 -0.59 1.59e-33 Total body bone mineral density; LIHC cis rs769267 0.930 rs4808208 chr19:19650096 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.63 0.38 2.36e-13 Tonsillectomy; LIHC cis rs9303401 0.659 rs7225896 chr17:56637337 T/C cg25039879 chr17:56429692 SUPT4H1 0.84 9.58 0.46 1.99e-19 Cognitive test performance; LIHC cis rs559928 0.606 rs61083753 chr11:63892665 C/T cg05555928 chr11:63887634 MACROD1 -0.51 -6.0 -0.31 5.1e-9 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7192380 0.651 rs6499239 chr16:69686748 G/A cg15192750 chr16:69999425 NA 0.36 5.72 0.3 2.28e-8 Sjögren's syndrome; LIHC cis rs892961 0.867 rs312909 chr17:75413954 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.44 0.37 8.37e-13 Airflow obstruction; LIHC cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg03517284 chr6:25882590 NA -0.65 -8.24 -0.41 3.72e-15 Intelligence (multi-trait analysis); LIHC cis rs12644436 0.711 rs4693190 chr4:88787765 G/A cg06891869 chr4:88767617 MEPE 0.42 7.6 0.38 2.93e-13 HIV-1 viral setpoint; LIHC cis rs78545713 0.536 rs80202565 chr6:26233882 C/G cg16070018 chr6:26224392 HIST1H3E 0.78 7.45 0.37 7.6e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs17270561 0.779 rs12209218 chr6:25887776 C/A cg17691542 chr6:26056736 HIST1H1C 0.83 9.81 0.47 3.64e-20 Iron status biomarkers; LIHC cis rs10464366 0.571 rs4723825 chr7:39157627 G/C cg10621924 chr7:39171070 POU6F2 0.42 6.51 0.33 2.67e-10 IgG glycosylation; LIHC cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.92 -9.29 -0.45 1.9e-18 Platelet count; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg11112892 chr5:131563589 P4HA2 0.49 6.2 0.32 1.59e-9 Hepatitis; LIHC cis rs7223966 1.000 rs8074771 chr17:61735865 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.57 0.33 1.83e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2932538 0.922 rs36029940 chr1:113106444 T/G cg22162597 chr1:113214053 CAPZA1 0.71 9.53 0.46 2.99e-19 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs763121 0.853 rs7289577 chr22:39042214 C/G cg06022373 chr22:39101656 GTPBP1 0.67 11.71 0.53 7.53e-27 Menopause (age at onset); LIHC cis rs2282802 0.685 rs2116790 chr5:139654115 G/A cg26211634 chr5:139558579 C5orf32 0.39 5.97 0.31 5.96e-9 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.22 0.45 3.17e-18 Bipolar disorder; LIHC cis rs861020 0.771 rs126280 chr1:210019824 A/G cg09163369 chr1:210001066 C1orf107 0.49 6.41 0.33 4.74e-10 Orofacial clefts; LIHC cis rs9916302 0.904 rs679995 chr17:37441679 A/T cg03013999 chr17:37608204 MED1 -0.34 -5.77 -0.3 1.76e-8 Glomerular filtration rate (creatinine); LIHC cis rs4975709 0.589 rs1466606 chr5:1865055 C/T cg14773178 chr5:1868261 NA 0.26 7.07 0.36 8.79e-12 Cardiovascular disease risk factors; LIHC trans rs2727020 0.755 rs652655 chr11:49251293 G/A cg03929089 chr4:120376271 NA 0.8 13.98 0.6 1.96e-35 Coronary artery disease; LIHC trans rs17433710 0.516 rs6689396 chr1:162676698 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.27 -0.32 1.09e-9 Dupuytren's disease; LIHC cis rs1728785 1.000 rs8058314 chr16:68584151 G/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs4908768 0.539 rs1318218 chr1:8658712 T/C cg20416874 chr1:8611966 RERE -0.63 -11.71 -0.53 7.32e-27 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7129220 0.512 rs1867136 chr11:10228843 C/T cg01453529 chr11:10209919 SBF2 -0.43 -7.88 -0.39 4.41e-14 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs6570726 0.791 rs1935612 chr6:145906090 T/A cg23711669 chr6:146136114 FBXO30 0.64 10.94 0.51 4.39e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2573652 0.722 rs11852383 chr15:100542765 C/T cg09918751 chr15:100517450 ADAMTS17 -0.68 -11.64 -0.53 1.36e-26 Height; LIHC cis rs798554 0.679 rs2527677 chr7:2882621 A/G cg04166393 chr7:2884313 GNA12 0.52 8.2 0.41 4.9e-15 Height; LIHC cis rs55823223 0.564 rs936396 chr17:73846829 C/G cg08125733 chr17:73851984 WBP2 0.85 12.53 0.56 6.5e-30 Psoriasis; LIHC cis rs7223966 0.921 rs67018565 chr17:61928055 C/A cg05941027 chr17:61774174 LIMD2 0.35 7.44 0.37 8.1e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs68170813 0.559 rs3801963 chr7:106898036 C/T cg02696742 chr7:106810147 HBP1 -0.53 -6.28 -0.32 1.05e-9 Coronary artery disease; LIHC cis rs13108904 0.775 rs2279282 chr4:1216033 G/C cg13395646 chr4:1353034 KIAA1530 -0.41 -5.96 -0.31 6.44e-9 Obesity-related traits; LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg07167872 chr1:205819463 PM20D1 0.71 10.31 0.49 7.13e-22 Menarche (age at onset); LIHC cis rs6674176 0.597 rs2352990 chr1:44393276 T/A cg12908607 chr1:44402522 ARTN -0.48 -8.16 -0.4 6.29e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs17539620 0.624 rs74551216 chr6:154840524 T/C cg17771515 chr6:154831774 CNKSR3 0.56 6.02 0.31 4.6e-9 Lipoprotein (a) levels; LIHC cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg07424592 chr7:64974309 NA 0.8 9.21 0.45 3.38e-18 Diabetic kidney disease; LIHC cis rs780096 0.546 rs715326 chr2:27725761 A/G cg27432699 chr2:27873401 GPN1 0.52 7.76 0.39 1.02e-13 Total body bone mineral density; LIHC cis rs2029362 0.611 rs10767665 chr11:27733858 C/T cg18117895 chr11:27722066 BDNF -0.38 -5.76 -0.3 1.86e-8 Total body bone mineral density; LIHC cis rs1967309 0.604 rs8061182 chr16:4070333 A/G cg00061520 chr16:4070371 ADCY9 0.37 6.38 0.33 5.81e-10 Response to Dalcetrapib treatment in acute coronary syndrome; LIHC cis rs1062177 0.694 rs2915816 chr5:151115857 G/A cg00977110 chr5:151150581 G3BP1 -0.5 -6.57 -0.33 1.93e-10 Preschool internalizing problems; LIHC cis rs10508774 1.000 rs55773420 chr10:32824910 T/C cg01819863 chr10:32635814 EPC1 0.65 6.03 0.31 4.19e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1552244 0.510 rs13075308 chr3:10034925 G/C cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs2153535 0.541 rs7774752 chr6:8468978 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7618501 0.669 rs3774758 chr3:49938227 C/G cg24110177 chr3:50126178 RBM5 -0.51 -7.95 -0.39 2.79e-14 Intelligence (multi-trait analysis); LIHC cis rs10791097 0.694 rs7106995 chr11:130758152 G/T cg14779329 chr11:130786720 SNX19 0.43 6.53 0.33 2.39e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2625529 0.816 rs8025504 chr15:72294757 C/T cg16672083 chr15:72433130 SENP8 -0.3 -5.75 -0.3 2e-8 Red blood cell count; LIHC cis rs12048904 0.533 rs1590580 chr1:101292668 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.67 10.39 0.49 3.61e-22 Multiple sclerosis; LIHC cis rs875971 0.862 rs778705 chr7:65861115 G/A cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.01 -24.63 -0.8 9.28e-78 Prudent dietary pattern; LIHC cis rs12188164 0.561 rs2721010 chr5:456915 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.48 7.19 0.36 4.03e-12 Cystic fibrosis severity; LIHC cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg13047869 chr3:10149882 C3orf24 0.52 6.68 0.34 9.54e-11 Alzheimer's disease; LIHC cis rs35110281 0.627 rs6518268 chr21:44967448 A/G cg01579765 chr21:45077557 HSF2BP -0.33 -6.23 -0.32 1.39e-9 Mean corpuscular volume; LIHC cis rs12702595 0.590 rs13244913 chr7:7264089 T/C cg04827551 chr7:7268805 C1GALT1 0.38 6.8 0.35 4.7e-11 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs10492096 0.947 rs10849482 chr12:6635274 G/A cg13857086 chr12:6580257 VAMP1 0.57 6.07 0.31 3.48e-9 Hip geometry; LIHC cis rs4144743 0.941 rs7211563 chr17:45324061 T/C cg18085866 chr17:45331354 ITGB3 -0.59 -8.53 -0.42 4.87e-16 Body mass index; LIHC cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg13047869 chr3:10149882 C3orf24 0.48 5.89 0.3 9.41e-9 Alzheimer's disease; LIHC cis rs12086130 0.892 rs59595057 chr1:51493428 A/G cg07174182 chr1:51127561 FAF1 -0.82 -9.27 -0.45 2.14e-18 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg00684032 chr4:1343700 KIAA1530 0.52 7.58 0.38 3.3e-13 Obesity-related traits; LIHC trans rs1499614 1.000 rs2707832 chr7:66136549 C/T cg10756647 chr7:56101905 PSPH 0.95 11.81 0.54 3.04e-27 Gout; LIHC trans rs561341 1.000 rs8077092 chr17:30281992 T/C cg20587970 chr11:113659929 NA -1.25 -10.81 -0.5 1.22e-23 Hip circumference adjusted for BMI; LIHC cis rs9814567 0.896 rs1357764 chr3:134344928 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.59 9.75 0.47 5.39e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4780401 0.609 rs9923954 chr16:11816855 G/T cg01061890 chr16:11836724 TXNDC11 -0.65 -10.47 -0.49 1.92e-22 Rheumatoid arthritis; LIHC cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.94 0.44 2.39e-17 Platelet count; LIHC cis rs10847980 0.590 rs79798267 chr12:123321819 A/T cg07706471 chr12:123319906 HIP1R 0.72 8.12 0.4 8.26e-15 Adiponectin levels; LIHC cis rs11577318 0.853 rs3795684 chr1:26632781 C/T cg18121669 chr1:26560928 CCDC21 0.52 8.2 0.41 5.05e-15 Granulocyte percentage of myeloid white cells; LIHC cis rs7917772 0.582 rs12782153 chr10:104368294 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.79 -0.39 8.02e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1577917 0.958 rs12196175 chr6:86779370 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.31 -0.37 1.84e-12 Response to antipsychotic treatment; LIHC trans rs4906332 1.000 rs12889703 chr14:103872951 T/A cg17675199 chr6:35436792 RPL10A 0.33 6.4 0.33 5.15e-10 Coronary artery disease; LIHC cis rs7959452 0.640 rs11177599 chr12:69721970 G/A cg20891283 chr12:69753455 YEATS4 0.79 15.01 0.63 1.83e-39 Blood protein levels; LIHC cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 11.68 0.53 9.51e-27 Alzheimer's disease; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg19687152 chr14:102968497 TECPR2 0.54 6.68 0.34 9.55e-11 Lung function (FEV1); LIHC trans rs875971 0.660 rs13224319 chr7:66007363 A/G cg26939375 chr7:64535504 NA 0.43 6.96 0.35 1.72e-11 Aortic root size; LIHC cis rs10504073 0.584 rs4873092 chr8:49974053 T/C cg00325661 chr8:49890786 NA 0.33 7.52 0.38 4.74e-13 Blood metabolite ratios; LIHC cis rs1419980 0.730 rs7132588 chr12:7754616 T/A cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC trans rs2243480 0.901 rs778730 chr7:65823325 T/A cg10756647 chr7:56101905 PSPH 1.03 12.46 0.56 1.23e-29 Diabetic kidney disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18311516 chr14:102514894 DYNC1H1 0.43 6.17 0.32 1.95e-9 Longevity; LIHC cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg25894440 chr7:65020034 NA 0.52 6.05 0.31 3.73e-9 Diabetic kidney disease; LIHC cis rs11955398 0.716 rs1379115 chr5:59997886 A/C cg02684056 chr5:59996105 DEPDC1B 0.4 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.721 rs11211163 chr1:46153548 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.74 0.39 1.11e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs867371 1.000 rs11855089 chr15:82447265 T/C cg18393722 chr15:85113863 UBE2QP1 -0.41 -7.0 -0.35 1.39e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs11122272 0.701 rs11582413 chr1:231530098 C/G cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs2637030 0.515 rs256103 chr5:53012475 A/G cg06476337 chr5:52856530 NDUFS4 0.42 6.73 0.34 6.99e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs13108904 0.518 rs4974602 chr4:1342391 C/T cg22903657 chr4:1355424 KIAA1530 -0.43 -6.34 -0.32 7.4e-10 Obesity-related traits; LIHC cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.31 -0.45 1.6e-18 Electroencephalogram traits; LIHC cis rs623264 0.920 rs668692 chr19:5469832 A/G cg03088458 chr19:5478473 NA -0.36 -5.81 -0.3 1.41e-8 Interleukin-2 receptor antagonist levels; LIHC cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg18230493 chr5:56204884 C5orf35 -0.45 -6.21 -0.32 1.55e-9 Initial pursuit acceleration; LIHC cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg26531700 chr6:26746687 NA 0.39 6.4 0.33 5.18e-10 Intelligence (multi-trait analysis); LIHC trans rs2270927 0.510 rs4352583 chr5:75576716 A/G cg13563193 chr19:33072644 PDCD5 0.99 8.99 0.44 1.66e-17 Mean corpuscular volume; LIHC cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg27170947 chr2:26402098 FAM59B 0.66 8.34 0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs9649213 0.574 rs34717219 chr7:97962271 A/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs10751667 0.580 rs7395515 chr11:1005160 C/T cg10932868 chr11:921992 NA 0.34 6.37 0.33 5.94e-10 Alzheimer's disease (late onset); LIHC cis rs17106184 1.000 rs72898946 chr1:50959262 A/C cg07174182 chr1:51127561 FAF1 -0.61 -6.81 -0.35 4.38e-11 Type 2 diabetes; LIHC cis rs2191566 0.960 rs6509133 chr19:44522913 A/G cg18700516 chr19:44507157 ZNF230 0.35 5.79 0.3 1.56e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs4586057 0.514 rs10881844 chr10:92648024 A/G cg14313238 chr10:92632228 RPP30 0.35 5.91 0.3 8.17e-9 Economic and political preferences (time); LIHC trans rs879568 0.708 rs644056 chr18:34270525 C/G cg16486109 chr11:613632 IRF7 0.39 6.05 0.31 3.82e-9 QRS duration; LIHC cis rs16958440 0.867 rs16949157 chr18:44691324 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs2531992 0.925 rs2531993 chr16:4014245 A/G cg05927578 chr16:4029543 ADCY9 0.57 6.31 0.32 8.61e-10 Waist circumference; LIHC cis rs7937840 0.501 rs4963459 chr11:61877137 G/A cg01969543 chr11:61895209 INCENP -0.43 -6.04 -0.31 4.04e-9 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00810945 chr16:21964237 UQCRC2 0.4 6.25 0.32 1.23e-9 Cognitive function; LIHC cis rs317689 0.513 rs317659 chr12:69686132 T/A cg14784868 chr12:69753453 YEATS4 0.66 10.65 0.5 4.59e-23 Response to diuretic therapy; LIHC cis rs6952808 0.707 rs13244345 chr7:1973004 A/G cg04267008 chr7:1944627 MAD1L1 -0.63 -9.92 -0.47 1.48e-20 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg00280220 chr17:61926910 NA 0.43 6.79 0.34 4.99e-11 Prudent dietary pattern; LIHC cis rs7845219 0.544 rs2123647 chr8:95931782 A/G cg16049864 chr8:95962084 TP53INP1 0.45 6.9 0.35 2.56e-11 Type 2 diabetes; LIHC cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg10360139 chr7:1886902 MAD1L1 -0.42 -6.51 -0.33 2.63e-10 Bipolar disorder and schizophrenia; LIHC cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg02475777 chr4:1388615 CRIPAK -0.47 -6.89 -0.35 2.74e-11 Obesity-related traits; LIHC trans rs2262909 0.962 rs17459246 chr19:22278121 T/C cg17074339 chr11:11642133 GALNTL4 0.44 6.9 0.35 2.6e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs7647973 0.593 rs58339610 chr3:49845006 T/A cg03060546 chr3:49711283 APEH -0.6 -7.01 -0.35 1.25e-11 Menarche (age at onset); LIHC cis rs7589728 1.000 rs7425670 chr2:88522028 C/T cg07952391 chr2:88470173 THNSL2 0.67 6.04 0.31 4.05e-9 Plasma clusterin levels; LIHC cis rs61990749 0.597 rs1978416 chr14:78227901 C/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.83 -0.39 5.99e-14 Fibroblast growth factor basic levels; LIHC cis rs4820294 1.000 rs7291867 chr22:38062112 C/G cg00142150 chr22:38071001 LGALS1 0.71 11.51 0.53 3.83e-26 Fat distribution (HIV); LIHC cis rs67311347 0.577 rs1880763 chr3:40283255 C/T cg18306943 chr3:40428807 ENTPD3 -0.38 -6.34 -0.32 7.46e-10 Renal cell carcinoma; LIHC cis rs1707322 0.927 rs11211194 chr1:46282084 C/T cg03146154 chr1:46216737 IPP 0.47 7.69 0.38 1.54e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11955398 0.625 rs12655515 chr5:59974098 G/C cg02684056 chr5:59996105 DEPDC1B 0.42 5.9 0.3 8.62e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg18306943 chr3:40428807 ENTPD3 0.42 7.43 0.37 8.93e-13 Renal cell carcinoma; LIHC cis rs8017423 0.845 rs114583024 chr14:90727628 T/C cg14092571 chr14:90743983 NA -0.38 -6.02 -0.31 4.54e-9 Mortality in heart failure; LIHC cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg14262678 chr6:151773367 RMND1;C6orf211 0.67 10.99 0.51 2.83e-24 Menarche (age at onset); LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg13409248 chr3:40428643 ENTPD3 -0.5 -8.4 -0.41 1.23e-15 Renal cell carcinoma; LIHC cis rs61863818 0.557 rs7898743 chr10:99153540 T/G cg20016023 chr10:99160130 RRP12 -0.35 -5.84 -0.3 1.19e-8 Monocyte percentage of white cells; LIHC cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg06453172 chr10:134556979 INPP5A -0.65 -8.41 -0.41 1.15e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs1005277 0.579 rs1614236 chr10:38502996 C/T cg23533926 chr12:111358616 MYL2 -0.33 -6.18 -0.32 1.81e-9 Extrinsic epigenetic age acceleration; LIHC cis rs921968 0.643 rs545779 chr2:219336108 A/G cg18887096 chr2:219472410 PLCD4 0.37 6.65 0.34 1.13e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2032447 0.639 rs198810 chr6:26128618 A/G cg12310025 chr6:25882481 NA 0.49 6.24 0.32 1.31e-9 Intelligence (multi-trait analysis); LIHC cis rs3213545 0.700 rs10849829 chr12:121470256 A/G cg02403541 chr12:121454288 C12orf43 -0.63 -12.08 -0.55 3.3e-28 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs10791097 0.694 rs10160281 chr11:130742788 T/C cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs763121 0.853 rs1043441 chr22:39130964 C/T cg14440974 chr22:39074834 NA -0.37 -6.18 -0.32 1.87e-9 Menopause (age at onset); LIHC trans rs5756813 1.000 rs1129448 chr22:38170026 G/A cg19894588 chr14:64061835 NA 0.68 10.38 0.49 4.1e-22 Optic cup area;Vertical cup-disc ratio; LIHC cis rs55823223 0.564 rs936391 chr17:73847799 A/G cg14829360 chr17:73884958 NA 0.44 6.97 0.35 1.67e-11 Psoriasis; LIHC cis rs2797685 0.898 rs3753503 chr1:7841971 G/A cg04725166 chr1:7887271 PER3 -0.44 -7.66 -0.38 1.94e-13 Crohn's disease; LIHC cis rs7312933 0.703 rs2406567 chr12:42551479 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 8.1 0.4 1e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2032447 0.507 rs478349 chr6:25894057 T/C cg07061783 chr6:25882402 NA -0.83 -9.96 -0.47 1.11e-20 Intelligence (multi-trait analysis); LIHC cis rs9733 0.569 rs11204691 chr1:150644339 A/T cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg02303361 chr19:47354240 AP2S1 0.37 6.06 0.31 3.5e-9 Metabolic traits; LIHC cis rs9503598 0.502 rs6939748 chr6:3430584 C/T cg00476032 chr6:3446245 SLC22A23 -0.32 -5.86 -0.3 1.08e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs10752881 1.000 rs10752886 chr1:182987248 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs2625529 0.824 rs4777475 chr15:72218206 C/T cg16672083 chr15:72433130 SENP8 -0.3 -5.72 -0.3 2.27e-8 Red blood cell count; LIHC trans rs1814175 0.715 rs10839409 chr11:49884647 G/T cg03929089 chr4:120376271 NA -0.89 -18.21 -0.7 2.9e-52 Height; LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs992157 0.672 rs2382829 chr2:219184617 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.21 0.48 1.49e-21 Colorectal cancer; LIHC cis rs1046896 0.586 rs9897951 chr17:80810662 T/C cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.36 0.33 6.53e-10 Glycated hemoglobin levels; LIHC cis rs10791097 0.694 rs6590520 chr11:130747386 C/G cg14779329 chr11:130786720 SNX19 0.4 6.15 0.32 2.14e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg18357526 chr6:26021779 HIST1H4A -0.87 -12.29 -0.55 5.42e-29 Intelligence (multi-trait analysis); LIHC cis rs11025559 0.812 rs10766678 chr11:20507180 A/G cg19653624 chr11:20408972 PRMT3 -0.48 -6.33 -0.32 7.74e-10 Pursuit maintenance gain; LIHC trans rs7178375 1.000 rs10163148 chr15:31212684 C/G cg04373760 chr16:53404718 NA 0.6 7.66 0.38 1.89e-13 Hypertriglyceridemia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21024969 chr6:163994355 QKI 0.33 6.28 0.32 1.03e-9 Pancreatic cancer; LIHC trans rs1005277 0.579 rs2474575 chr10:38387901 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9325144 0.600 rs2171405 chr12:38741030 G/T cg26384229 chr12:38710491 ALG10B -0.55 -7.6 -0.38 2.88e-13 Morning vs. evening chronotype; LIHC cis rs929354 0.772 rs1182362 chr7:157019535 A/G cg17757837 chr7:157058334 UBE3C -0.73 -11.97 -0.54 7.94e-28 Body mass index; LIHC cis rs12908161 0.959 rs62019472 chr15:85331493 A/G cg17507749 chr15:85114479 UBE2QP1 0.61 6.85 0.35 3.51e-11 Schizophrenia; LIHC cis rs4878497 0.532 rs10813817 chr9:32448745 T/C cg14296220 chr9:32431791 ACO1 0.55 9.13 0.44 5.91e-18 Inflammatory skin disease; LIHC cis rs6728642 0.908 rs7588921 chr2:98021001 C/T cg26665480 chr2:98280029 ACTR1B -0.63 -6.1 -0.31 2.92e-9 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs763121 0.853 rs5757208 chr22:39049230 A/C cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs7208859 0.673 rs11651802 chr17:29159660 T/C cg13385521 chr17:29058706 SUZ12P 0.81 7.87 0.39 4.84e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1814175 0.817 rs10839358 chr11:49770972 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.85 0.35 3.39e-11 Height; LIHC cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.86 0.3 1.12e-8 Aortic root size; LIHC cis rs875971 0.789 rs7808013 chr7:66071196 A/G cg18876405 chr7:65276391 NA -0.34 -6.24 -0.32 1.3e-9 Aortic root size; LIHC cis rs2153535 0.580 rs9405391 chr6:8466548 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs9611565 0.592 rs5996038 chr22:41965300 T/C cg03806693 chr22:41940476 POLR3H -0.87 -9.75 -0.47 5.67e-20 Vitiligo; LIHC cis rs4759375 1.000 rs10082867 chr12:123796997 A/G cg00376283 chr12:123451042 ABCB9 -0.5 -6.4 -0.33 5.02e-10 HDL cholesterol; LIHC cis rs11098499 0.821 rs3775852 chr4:120454556 A/G cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs1395 0.744 rs72817536 chr2:27497548 A/G cg22903471 chr2:27725779 GCKR -0.45 -6.07 -0.31 3.33e-9 Blood metabolite levels; LIHC trans rs801193 0.613 rs2659900 chr7:66184443 G/C cg10756647 chr7:56101905 PSPH 0.47 6.95 0.35 1.81e-11 Aortic root size; LIHC cis rs7647973 0.731 rs7617480 chr3:49210732 G/T cg07636037 chr3:49044803 WDR6 -0.51 -6.3 -0.32 9.22e-10 Menarche (age at onset); LIHC cis rs9457247 1.000 rs239935 chr6:167411788 G/A cg07741184 chr6:167504864 NA 0.29 6.7 0.34 8.43e-11 Crohn's disease; LIHC cis rs265548 0.510 rs28415068 chr19:17910582 T/A cg21960279 chr19:17905606 B3GNT3 0.51 7.85 0.39 5.56e-14 Tumor biomarkers; LIHC cis rs11711311 1.000 rs9865435 chr3:113450046 G/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.39 0.45 8.39e-19 IgG glycosylation; LIHC cis rs9388451 0.626 rs3799708 chr6:126078530 C/T cg05901451 chr6:126070800 HEY2 -0.66 -14.1 -0.61 6.37e-36 Brugada syndrome; LIHC cis rs860295 0.967 rs6665227 chr1:155710460 T/C cg02153340 chr1:155202674 NA -0.31 -5.72 -0.3 2.38e-8 Body mass index; LIHC trans rs8002861 0.935 rs7318147 chr13:44445153 C/G cg18090489 chr13:45992445 SLC25A30 0.48 6.52 0.33 2.48e-10 Leprosy; LIHC cis rs2204008 0.743 rs11182052 chr12:38450421 T/C cg26384229 chr12:38710491 ALG10B 0.62 8.66 0.42 1.95e-16 Bladder cancer; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.09 0.55 2.94e-28 Prudent dietary pattern; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26762173 chr8:28351567 FZD3 -0.58 -6.56 -0.33 2e-10 Systolic blood pressure; LIHC cis rs11867934 0.577 rs9893676 chr17:17054951 C/G cg26176665 chr17:16994978 MPRIP 0.43 6.09 0.31 2.98e-9 Diabetic retinopathy; LIHC cis rs7959452 0.530 rs12811632 chr12:69755003 G/A cg20891283 chr12:69753455 YEATS4 0.9 19.13 0.72 5.41e-56 Blood protein levels; LIHC cis rs57590327 0.555 rs13099615 chr3:81729101 T/A cg07356753 chr3:81810745 GBE1 -0.55 -8.46 -0.42 7.81e-16 Extraversion; LIHC cis rs1865760 0.566 rs9358902 chr6:26058570 C/G cg18357526 chr6:26021779 HIST1H4A 0.46 6.78 0.34 5.44e-11 Height; LIHC cis rs8067354 0.574 rs1292035 chr17:57989557 G/A cg02344993 chr17:57696989 CLTC 0.67 10.55 0.5 1.06e-22 Hemoglobin concentration; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.21 -0.32 1.56e-9 Diastolic blood pressure; LIHC cis rs116248771 0.739 rs73156425 chr3:158345677 G/A cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.75e-10 diarrhoeal disease at age 2; LIHC cis rs644799 0.710 rs473852 chr11:95568757 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.72 11.97 0.54 8.45e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs3106136 0.678 rs12646487 chr4:95279907 T/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.92 0.3 7.93e-9 Capecitabine sensitivity; LIHC cis rs986417 1.000 rs2351176 chr14:61073731 A/T cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg14709524 chr16:89940631 TCF25 0.5 6.53 0.33 2.36e-10 Skin colour saturation; LIHC cis rs1506636 0.720 rs2456552 chr7:123441400 A/G cg03229431 chr7:123269106 ASB15 0.36 7.55 0.38 3.97e-13 Plateletcrit;Platelet count; LIHC cis rs6537837 0.701 rs12021920 chr1:110147287 C/T cg05049280 chr1:110155535 GNAT2 0.48 5.72 0.3 2.39e-8 Major depressive disorder; LIHC cis rs6988636 0.818 rs1713733 chr8:124199458 A/G cg15893493 chr8:124194847 FAM83A -0.67 -6.9 -0.35 2.61e-11 Urinary uromodulin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04987883 chr5:153826560 SAP30L 0.46 6.06 0.31 3.51e-9 Lung function (FEV1/FVC); LIHC cis rs2115630 0.645 rs6496284 chr15:85178270 A/G cg11189052 chr15:85197271 WDR73 -0.54 -8.3 -0.41 2.49e-15 P wave terminal force; LIHC cis rs3731896 0.571 rs77251296 chr2:220193172 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.56 6.52 0.33 2.58e-10 Educational attainment; LIHC cis rs2235642 0.859 rs12599207 chr16:1606445 A/G cg03034668 chr16:1723424 CRAMP1L -0.42 -7.38 -0.37 1.24e-12 Coronary artery disease; LIHC cis rs739401 0.572 rs389128 chr11:3083873 G/T cg08508325 chr11:3079039 CARS -0.35 -7.34 -0.37 1.55e-12 Longevity; LIHC cis rs6500602 0.702 rs3789038 chr16:4546586 C/G cg08645402 chr16:4508243 NA -0.45 -8.28 -0.41 2.77e-15 Schizophrenia; LIHC cis rs1577917 0.629 rs9450285 chr6:86208096 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.42 7.69 0.38 1.53e-13 Response to antipsychotic treatment; LIHC cis rs2297440 0.506 rs2236504 chr20:62224762 C/T cg16989086 chr20:62203971 PRIC285 0.57 8.2 0.41 5.08e-15 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC trans rs910316 0.737 rs175045 chr14:75475275 A/C cg07213720 chr6:35227408 ZNF76 -0.45 -6.35 -0.32 6.82e-10 Height; LIHC cis rs1707322 0.686 rs3014251 chr1:46077428 G/C cg03146154 chr1:46216737 IPP -0.57 -9.38 -0.45 9.69e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12701220 0.948 rs10275712 chr7:1082918 G/A cg26769984 chr7:1090371 C7orf50 0.63 7.99 0.4 2.09e-14 Bronchopulmonary dysplasia; LIHC cis rs9611565 0.625 rs2076199 chr22:41903743 G/T cg03806693 chr22:41940476 POLR3H -0.52 -6.81 -0.35 4.47e-11 Vitiligo; LIHC cis rs5769765 1.000 rs768619 chr22:50287266 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.15 -0.44 5.07e-18 Schizophrenia; LIHC cis rs7223966 1.000 rs11657306 chr17:61704822 G/A cg23903597 chr17:61704154 MAP3K3 -0.44 -6.04 -0.31 4.04e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6456156 0.603 rs2345754 chr6:167484361 T/C cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.07e-9 Primary biliary cholangitis; LIHC cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 10.71 0.5 2.92e-23 Platelet count; LIHC cis rs10751667 0.666 rs7950967 chr11:955638 G/A cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.09e-12 Alzheimer's disease (late onset); LIHC cis rs17102423 0.594 rs7159443 chr14:65550816 T/A cg16583315 chr14:65563665 MAX -0.39 -7.96 -0.4 2.56e-14 Obesity-related traits; LIHC cis rs2404602 0.552 rs11630185 chr15:76959783 A/T cg03037974 chr15:76606532 NA -0.51 -8.06 -0.4 1.32e-14 Blood metabolite levels; LIHC trans rs79976124 0.879 rs12214948 chr6:66633603 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.62 6.46 0.33 3.68e-10 Type 2 diabetes; LIHC cis rs2273156 0.706 rs7153550 chr14:35501800 A/G cg16230307 chr14:35515116 FAM177A1 -0.43 -6.16 -0.32 2.01e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg12463550 chr7:65579703 CRCP 0.69 7.15 0.36 5.29e-12 Diabetic kidney disease; LIHC cis rs11931598 0.511 rs35772786 chr4:7021211 T/G cg02503808 chr4:7069936 GRPEL1 0.49 7.68 0.38 1.73e-13 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17996757 chr7:131013207 MKLN1 0.44 6.36 0.33 6.4e-10 Cognitive function; LIHC cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs918629 0.530 rs2042340 chr5:95235193 T/C cg10483112 chr5:95245456 ELL2 -0.37 -6.74 -0.34 6.85e-11 IgG glycosylation; LIHC cis rs7618501 0.538 rs9856572 chr3:50109073 A/T cg24110177 chr3:50126178 RBM5 0.51 8.2 0.41 4.78e-15 Intelligence (multi-trait analysis); LIHC cis rs7572733 0.534 rs1464211 chr2:198798630 G/A cg03934865 chr2:198174659 NA 0.46 6.79 0.34 5.08e-11 Dermatomyositis; LIHC cis rs9399135 0.967 rs2327580 chr6:135364417 A/C cg24558204 chr6:135376177 HBS1L 0.44 7.23 0.36 3.16e-12 Red blood cell count; LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs17106184 0.901 rs72904745 chr1:51363273 C/G cg07174182 chr1:51127561 FAF1 -0.76 -7.66 -0.38 1.97e-13 Type 2 diabetes; LIHC cis rs7843479 0.562 rs6988010 chr8:21859084 G/A cg17168535 chr8:21777572 XPO7 0.57 9.99 0.48 8.76e-21 Mean corpuscular volume; LIHC cis rs10416265 0.528 rs10420258 chr19:33602757 C/T cg17764715 chr19:33622953 WDR88 0.49 6.48 0.33 3.28e-10 Bone properties (heel); LIHC cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg02187348 chr16:89574699 SPG7 0.64 10.33 0.49 5.92e-22 Multiple myeloma (IgH translocation); LIHC cis rs55665837 0.519 rs1451677 chr11:14746012 A/C cg00085434 chr11:14927489 NA 0.41 5.89 0.3 9.43e-9 Vitamin D levels; LIHC cis rs12579753 0.871 rs1922540 chr12:82197496 A/G cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC cis rs9911578 0.967 rs57869245 chr17:57106630 A/G cg12560992 chr17:57184187 TRIM37 -0.94 -16.87 -0.67 6.63e-47 Intelligence (multi-trait analysis); LIHC cis rs8067354 0.681 rs76856339 chr17:57800966 G/A cg02344993 chr17:57696989 CLTC 0.72 12.04 0.55 4.49e-28 Hemoglobin concentration; LIHC cis rs801193 1.000 rs2286684 chr7:66129830 G/T cg14393609 chr7:65229607 NA -0.37 -5.83 -0.3 1.27e-8 Aortic root size; LIHC cis rs4555082 0.874 rs2816606 chr14:105716034 C/T cg13114125 chr14:105738426 BRF1 -0.78 -9.9 -0.47 1.82e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs9640161 0.789 rs10952250 chr7:150025966 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.51 -9.09 -0.44 8.45e-18 Blood protein levels;Circulating chemerin levels; LIHC trans rs61931739 0.500 rs12371415 chr12:34521362 C/T cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs1801251 1.000 rs6747645 chr2:233571033 C/T cg25237894 chr2:233734115 C2orf82 -0.49 -9.49 -0.46 4.1e-19 Coronary artery disease; LIHC cis rs644799 1.000 rs487609 chr11:95588102 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.63 0.46 1.41e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs738322 0.600 rs6001035 chr22:38562425 A/G cg25457927 chr22:38595422 NA -0.36 -8.65 -0.42 2.07e-16 Cutaneous nevi; LIHC cis rs1728785 0.901 rs2862781 chr16:68639234 A/T cg02972257 chr16:68554789 NA -0.5 -5.73 -0.3 2.24e-8 Ulcerative colitis; LIHC cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg07424592 chr7:64974309 NA 0.76 8.83 0.43 5.38e-17 Diabetic kidney disease; LIHC cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.94 0.31 6.86e-9 Menopause (age at onset); LIHC cis rs12477438 1.000 rs6542873 chr2:99824965 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.65 -8.52 -0.42 5.33e-16 Chronic sinus infection; LIHC cis rs4718428 0.672 rs12530806 chr7:66390724 A/G cg18252515 chr7:66147081 NA -0.69 -9.52 -0.46 3.37e-19 Corneal structure; LIHC cis rs6089584 1.000 rs6089584 chr20:60564086 G/C cg13770153 chr20:60521292 NA -0.36 -7.02 -0.35 1.24e-11 Body mass index; LIHC cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg05555928 chr11:63887634 MACROD1 0.53 7.28 0.37 2.27e-12 Mean platelet volume; LIHC cis rs812925 0.519 rs1186706 chr2:61673394 G/T cg14146966 chr2:61757674 XPO1 0.39 6.44 0.33 4.04e-10 Immature fraction of reticulocytes; LIHC cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg20887711 chr4:1340912 KIAA1530 0.66 10.09 0.48 3.92e-21 Longevity; LIHC cis rs68170813 0.559 rs79978998 chr7:106845482 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 6.9 0.35 2.6e-11 Bipolar disorder; LIHC cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 10.69 0.5 3.35e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs60871478 1.000 rs62432253 chr7:802928 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.54 6.3 0.32 8.93e-10 Cerebrospinal P-tau181p levels; LIHC cis rs4423214 0.918 rs11233789 chr11:71181085 A/G cg24826892 chr11:71159390 DHCR7 0.47 6.21 0.32 1.51e-9 Vitamin D levels; LIHC cis rs4319547 0.656 rs7294559 chr12:122837564 C/A cg23029597 chr12:123009494 RSRC2 -0.53 -7.52 -0.38 4.76e-13 Body mass index; LIHC cis rs12477438 1.000 rs12053372 chr2:99810055 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.68 -7.52 -0.38 4.85e-13 Chronic sinus infection; LIHC cis rs2576037 0.526 rs2257027 chr18:44566990 A/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.48 7.0 0.35 1.34e-11 Personality dimensions; LIHC cis rs12403795 1.000 rs12403795 chr1:150278389 A/G cg15654264 chr1:150340011 RPRD2 0.46 6.21 0.32 1.51e-9 Illicit drug use; LIHC cis rs4808199 0.895 rs10421505 chr19:19459554 C/T cg21559469 chr19:19431446 KIAA0892;SF4 0.43 5.87 0.3 1.02e-8 Nonalcoholic fatty liver disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05680085 chr2:227700568 RHBDD1 -0.43 -6.28 -0.32 1.05e-9 Cognitive function; LIHC cis rs7647973 0.961 rs11130186 chr3:49275828 A/G cg07636037 chr3:49044803 WDR6 0.51 6.5 0.33 2.78e-10 Menarche (age at onset); LIHC cis rs4474465 1.000 rs2063727 chr11:78183882 T/A cg02023728 chr11:77925099 USP35 0.34 6.14 0.32 2.28e-9 Alzheimer's disease (survival time); LIHC cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg03396347 chr1:1875803 NA -0.49 -8.84 -0.43 4.99e-17 Body mass index; LIHC cis rs1577917 0.876 rs4618490 chr6:86518403 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.26 -0.41 3.27e-15 Response to antipsychotic treatment; LIHC cis rs11761441 0.669 rs13241486 chr7:79536 G/C cg22368281 chr7:82270 NA 0.27 5.84 0.3 1.19e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs57908212 1 rs57908212 chr19:2161321 T/C cg09261902 chr19:2140048 AP3D1 0.38 6.38 0.33 5.78e-10 Red blood cell count;Hemoglobin concentration;Hematocrit; LIHC cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg11644478 chr21:40555479 PSMG1 0.81 10.32 0.49 6.41e-22 Cognitive function; LIHC cis rs4819052 0.851 rs8126930 chr21:46671715 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 11.16 0.52 7.02e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs12752401 0.867 rs67349818 chr1:103030560 T/C cg03332897 chr19:740442 PALM 0.46 6.13 0.31 2.4e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs35110281 0.807 rs2838326 chr21:45014315 C/T cg21573476 chr21:45109991 RRP1B -0.48 -9.34 -0.45 1.28e-18 Mean corpuscular volume; LIHC cis rs9814567 0.963 rs9844537 chr3:134238341 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7614311 0.731 rs56126667 chr3:63866286 A/G cg22134162 chr3:63841271 THOC7 -0.56 -6.21 -0.32 1.57e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs35110281 0.667 rs7282405 chr21:45123611 C/G cg21573476 chr21:45109991 RRP1B -0.51 -9.65 -0.46 1.21e-19 Mean corpuscular volume; LIHC cis rs34779708 0.966 rs12775799 chr10:35488264 C/T cg03585969 chr10:35415529 CREM 0.85 12.81 0.57 6.11e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg11494091 chr17:61959527 GH2 0.45 8.13 0.4 7.75e-15 Prudent dietary pattern; LIHC cis rs7447593 0.518 rs4074995 chr5:176797343 C/T cg05207973 chr5:176823642 SLC34A1 0.33 5.98 0.31 5.51e-9 Urinary electrolytes (magnesium/calcium ratio); LIHC trans rs11098499 0.820 rs28394116 chr4:120524283 T/G cg25214090 chr10:38739885 LOC399744 0.6 9.72 0.47 7.19e-20 Corneal astigmatism; LIHC cis rs9534288 0.700 rs9316178 chr13:46570449 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs67311347 1.000 rs7636719 chr3:40432084 C/T cg00656387 chr3:40428638 ENTPD3 0.41 6.85 0.35 3.4e-11 Renal cell carcinoma; LIHC trans rs2243480 0.803 rs35480979 chr7:65357084 A/G cg10756647 chr7:56101905 PSPH 1.09 13.38 0.59 4.07e-33 Diabetic kidney disease; LIHC cis rs8180040 0.620 rs11715121 chr3:47072621 T/A cg16586182 chr3:47516702 SCAP 0.47 8.57 0.42 3.7e-16 Colorectal cancer; LIHC cis rs6545883 0.759 rs777585 chr2:61412559 A/G cg14146966 chr2:61757674 XPO1 -0.38 -6.43 -0.33 4.38e-10 Tuberculosis; LIHC cis rs2559856 1.000 rs2695291 chr12:102087543 G/A cg12924262 chr12:102091054 CHPT1 0.47 7.29 0.37 2.1e-12 Blood protein levels; LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg21548813 chr6:291882 DUSP22 -0.56 -7.59 -0.38 3.12e-13 Menopause (age at onset); LIHC cis rs6867032 1.000 rs10462750 chr5:2012963 A/G cg26168224 chr5:2018326 NA 0.32 8.06 0.4 1.26e-14 Gut microbiome composition (winter); LIHC cis rs7917772 0.582 rs7091252 chr10:104328859 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.17e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs240764 0.817 rs239237 chr6:101094940 A/G cg09795085 chr6:101329169 ASCC3 0.53 7.48 0.37 6.49e-13 Neuroticism; LIHC cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg04025307 chr7:1156635 C7orf50 0.65 11.36 0.52 1.36e-25 Longevity;Endometriosis; LIHC cis rs988712 0.672 rs35038967 chr11:27703480 T/A cg18117895 chr11:27722066 BDNF 0.54 7.46 0.37 7.35e-13 Obesity; LIHC cis rs8180040 0.903 rs2276854 chr3:47276968 C/T cg16586182 chr3:47516702 SCAP -0.54 -9.77 -0.47 4.62e-20 Colorectal cancer; LIHC cis rs6456156 0.565 rs2181058 chr6:167465330 A/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.68 -0.42 1.69e-16 Primary biliary cholangitis; LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg24209194 chr3:40518798 ZNF619 0.63 9.66 0.46 1.09e-19 Renal cell carcinoma; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg22903471 chr2:27725779 GCKR -0.5 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs9486715 1.000 rs11153082 chr6:97059666 A/G cg18709589 chr6:96969512 KIAA0776 -0.36 -6.17 -0.32 1.88e-9 Headache; LIHC cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg03396347 chr1:1875803 NA -0.48 -8.96 -0.44 2.06e-17 Body mass index; LIHC cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.93 9.08 0.44 8.84e-18 Platelet count; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg26668828 chr6:292823 DUSP22 -0.6 -8.17 -0.4 5.85e-15 Menopause (age at onset); LIHC cis rs7647973 1.000 rs9842132 chr3:49427933 G/A cg07636037 chr3:49044803 WDR6 -0.53 -6.44 -0.33 4.07e-10 Menarche (age at onset); LIHC cis rs61990749 0.597 rs11624101 chr14:78138059 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.61 -10.06 -0.48 4.99e-21 Fibroblast growth factor basic levels; LIHC cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs611744 0.967 rs2600615 chr8:109201170 G/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs7772486 0.622 rs1292333 chr6:145982344 C/T cg23711669 chr6:146136114 FBXO30 -0.69 -12.17 -0.55 1.47e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs7635838 0.590 rs2256773 chr3:11386329 C/G cg00170343 chr3:11313890 ATG7 0.59 9.76 0.47 5.07e-20 HDL cholesterol; LIHC cis rs9905704 0.647 rs3809723 chr17:57061978 T/G cg12560992 chr17:57184187 TRIM37 0.68 9.99 0.48 8.82e-21 Testicular germ cell tumor; LIHC cis rs4925386 1.000 rs1889201 chr20:60923075 C/T cg24112000 chr20:60950667 NA 0.43 6.78 0.34 5.28e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs4148883 0.675 rs10015824 chr4:100074544 C/G cg12011299 chr4:100065546 ADH4 0.37 7.33 0.37 1.66e-12 Alcohol dependence; LIHC cis rs6942756 0.876 rs2303303 chr7:129019736 G/A cg02491457 chr7:128862824 NA -0.59 -8.98 -0.44 1.88e-17 White matter hyperintensity burden; LIHC cis rs9611565 0.512 rs6519289 chr22:42170432 A/C cg03806693 chr22:41940476 POLR3H 0.96 10.08 0.48 4.42e-21 Vitiligo; LIHC cis rs2075371 0.966 rs2544224 chr7:133995832 A/G cg11752832 chr7:134001865 SLC35B4 0.52 7.63 0.38 2.29e-13 Mean platelet volume; LIHC cis rs1005277 0.579 rs1780130 chr10:38485378 T/A cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7.1e-9 Extrinsic epigenetic age acceleration; LIHC trans rs2727020 0.729 rs2866328 chr11:49282421 A/G cg15704280 chr7:45808275 SEPT13 0.9 16.38 0.66 6.1e-45 Coronary artery disease; LIHC cis rs7249142 0.549 rs539 chr19:19287802 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -6.99 -0.35 1.44e-11 IgG glycosylation; LIHC cis rs1801251 0.778 rs2675957 chr2:233754364 C/T cg25237894 chr2:233734115 C2orf82 -0.59 -11.21 -0.52 4.82e-25 Coronary artery disease; LIHC cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg05590025 chr7:65112418 INTS4L2 -0.67 -7.36 -0.37 1.34e-12 Diabetic kidney disease; LIHC cis rs10847980 0.590 rs58182048 chr12:123287708 C/T cg22842854 chr12:123319900 HIP1R 0.91 9.9 0.47 1.79e-20 Adiponectin levels; LIHC cis rs9790314 1.000 rs189270 chr3:161063504 T/C cg03342759 chr3:160939853 NMD3 -0.69 -8.31 -0.41 2.35e-15 Morning vs. evening chronotype; LIHC cis rs1577917 0.771 rs9362239 chr6:86429263 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.38 6.96 0.35 1.7e-11 Response to antipsychotic treatment; LIHC cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg24879335 chr3:133465180 TF 0.28 6.45 0.33 3.83e-10 Iron status biomarkers; LIHC cis rs1983891 0.955 rs4714479 chr6:41518807 A/G cg20194872 chr6:41519635 FOXP4 0.4 6.51 0.33 2.76e-10 Prostate cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg03778895 chr13:50699716 DLEU2 -0.41 -6.65 -0.34 1.16e-10 Calcium levels; LIHC cis rs1568889 0.838 rs4572130 chr11:28371794 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.03 0.6 1.24e-35 Bipolar disorder; LIHC cis rs6665290 0.935 rs12403236 chr1:227196502 C/G cg10327440 chr1:227177885 CDC42BPA -1.19 -26.83 -0.82 3.79e-86 Myeloid white cell count; LIHC cis rs11031096 0.678 rs12222136 chr11:4180148 T/C cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.46e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs1814175 0.645 rs10128731 chr11:50023554 G/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs801193 1.000 rs7783924 chr7:66209057 A/C cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.5e-9 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21023284 chr11:6624872 ILK;RRP8 0.52 6.73 0.34 7.28e-11 Lung function (FEV1/FVC); LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg21782813 chr7:2030301 MAD1L1 0.56 10.27 0.49 9.91e-22 Bipolar disorder and schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11120115 chr7:98649861 SMURF1 0.46 7.02 0.35 1.2e-11 Longevity; LIHC cis rs3768617 0.510 rs10797842 chr1:183081867 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 10.08 0.48 4.36e-21 Fuchs's corneal dystrophy; LIHC cis rs6499255 0.951 rs75815213 chr16:69702854 C/T cg15192750 chr16:69999425 NA 0.44 6.74 0.34 6.73e-11 IgE levels; LIHC cis rs72781680 1.000 rs72796357 chr2:24160131 A/G cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs963731 0.649 rs297159 chr2:39328827 C/T cg04010122 chr2:39346883 SOS1 -0.75 -6.21 -0.32 1.55e-9 Corticobasal degeneration; LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg16327326 chr16:1662895 IFT140 -0.42 -6.21 -0.32 1.56e-9 Bipolar disorder; LIHC cis rs735396 0.770 rs2257764 chr12:121446446 T/A cg02403541 chr12:121454288 C12orf43 -0.52 -9.17 -0.44 4.43e-18 N-glycan levels; LIHC cis rs12451471 0.637 rs7567 chr17:78093549 G/T cg24585782 chr17:78113791 EIF4A3 -0.45 -5.99 -0.31 5.19e-9 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs7100689 0.646 rs10788562 chr10:82072310 C/T cg01528321 chr10:82214614 TSPAN14 -0.79 -10.67 -0.5 3.86e-23 Post bronchodilator FEV1; LIHC cis rs8114671 0.562 rs6060064 chr20:33406339 C/G cg07148914 chr20:33460835 GGT7 -0.61 -9.01 -0.44 1.44e-17 Height; LIHC cis rs9921222 0.500 rs11648673 chr16:377794 G/A cg26944245 chr16:421049 TMEM8A;MRPL28 0.43 7.18 0.36 4.3e-12 Bone mineral density (spine);Bone mineral density; LIHC cis rs1461503 0.900 rs10892935 chr11:122838590 C/T cg14473756 chr11:122847823 NA -0.37 -6.67 -0.34 1.02e-10 Menarche (age at onset); LIHC cis rs67460515 0.528 rs11915989 chr3:160902259 A/G cg03342759 chr3:160939853 NMD3 -0.61 -9.18 -0.44 4.21e-18 Parkinson's disease; LIHC trans rs3176789 0.647 rs7309767 chr12:9920899 G/T cg18988856 chr7:99425577 CYP3A43 0.19 6.15 0.32 2.14e-9 Lymphocyte percentage of white cells;Neutrophil percentage of white cells; LIHC trans rs2727020 0.734 rs1164664 chr11:49295542 T/G cg03929089 chr4:120376271 NA 0.67 9.49 0.46 4.02e-19 Coronary artery disease; LIHC trans rs7618501 0.633 rs9861216 chr3:50059339 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.55 -8.97 -0.44 2.02e-17 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs4819044 chr21:46660118 G/A cg11663144 chr21:46675770 NA -0.33 -6.16 -0.32 2.03e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.9 0.3 8.84e-9 Menopause (age at onset); LIHC cis rs3806843 0.868 rs2531342 chr5:140130612 C/T cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7582180 0.614 rs10193204 chr2:101004540 A/G cg14675211 chr2:100938903 LONRF2 -0.56 -8.11 -0.4 9.32e-15 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.966 rs3806842 chr5:140212676 C/T cg26395211 chr5:140044315 WDR55 -0.41 -6.04 -0.31 3.93e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs61931739 0.534 rs11052960 chr12:33997754 A/T cg26384229 chr12:38710491 ALG10B 0.49 6.79 0.34 5.01e-11 Morning vs. evening chronotype; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg05665937 chr4:1216051 CTBP1 0.45 5.93 0.31 7.5e-9 Obesity-related traits; LIHC cis rs3734219 0.506 rs13197104 chr6:3355944 T/C cg18842474 chr6:3356384 SLC22A23 0.41 6.68 0.34 9.47e-11 Red cell distribution width; LIHC cis rs769267 0.965 rs2905425 chr19:19475717 G/C cg03709012 chr19:19516395 GATAD2A -1.0 -17.68 -0.69 3.86e-50 Tonsillectomy; LIHC cis rs116095464 0.558 rs55664502 chr5:270485 T/C cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg02564969 chr6:151773285 C6orf211;RMND1 0.44 6.48 0.33 3.28e-10 Menarche (age at onset); LIHC cis rs4423214 1.000 rs7944926 chr11:71165625 A/G cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC trans rs11098499 0.779 rs7699346 chr4:120310542 C/T cg25214090 chr10:38739885 LOC399744 0.56 8.86 0.43 4.29e-17 Corneal astigmatism; LIHC cis rs28830936 0.966 rs62002090 chr15:42092326 C/T cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.15 -0.32 2.13e-9 Diastolic blood pressure; LIHC cis rs7552404 1.000 rs211723 chr1:76103030 C/T cg10523679 chr1:76189770 ACADM -0.63 -8.64 -0.42 2.13e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2841277 0.712 rs2841280 chr14:105393556 G/C cg15352829 chr14:105391018 PLD4 0.43 8.77 0.43 8.68e-17 Rheumatoid arthritis; LIHC cis rs4474465 1.000 rs12280198 chr11:78161361 C/T cg27205649 chr11:78285834 NARS2 -0.38 -5.72 -0.3 2.29e-8 Alzheimer's disease (survival time); LIHC cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg22963979 chr7:1858916 MAD1L1 -0.43 -6.83 -0.35 3.81e-11 Bipolar disorder and schizophrenia; LIHC trans rs2727020 0.595 rs10466496 chr11:49501514 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -22.14 -0.77 5.15e-68 Coronary artery disease; LIHC cis rs8060686 0.668 rs2418739 chr16:68092850 G/C cg05110241 chr16:68378359 PRMT7 -0.52 -6.35 -0.32 6.81e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs10484885 0.824 rs72919954 chr6:90515665 T/A cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.69 -0.34 8.94e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2737618 0.674 rs2249150 chr1:200083654 G/A cg21825944 chr1:200113062 NR5A2 -0.48 -8.09 -0.4 1.05e-14 Uric acid levels; LIHC cis rs10492096 0.947 rs61918020 chr12:6605514 C/T cg13857086 chr12:6580257 VAMP1 0.58 6.14 0.31 2.32e-9 Hip geometry; LIHC cis rs9473924 1.000 rs6922746 chr6:50889828 A/T cg14470998 chr6:50812995 TFAP2B 0.49 7.35 0.37 1.52e-12 Body mass index; LIHC cis rs67460515 0.563 rs73023235 chr3:160864123 G/A cg03342759 chr3:160939853 NMD3 -0.62 -9.01 -0.44 1.5e-17 Parkinson's disease; LIHC cis rs16854884 0.710 rs1867607 chr3:143809274 T/C cg06585982 chr3:143692056 C3orf58 0.42 5.94 0.31 7.14e-9 Economic and political preferences (feminism/equality); LIHC cis rs4654899 1.000 rs7522722 chr1:21481840 G/A cg08539965 chr1:21396338 EIF4G3 0.33 5.79 0.3 1.58e-8 Superior frontal gyrus grey matter volume; LIHC cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg07424592 chr7:64974309 NA -0.8 -9.29 -0.45 1.82e-18 Diabetic kidney disease; LIHC cis rs2976388 1.000 rs10216533 chr8:143763690 G/A cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs1552244 0.882 rs56332224 chr3:10037321 G/A cg00149659 chr3:10157352 C3orf10 0.53 6.02 0.31 4.48e-9 Alzheimer's disease; LIHC cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg16405210 chr4:1374714 KIAA1530 -0.93 -15.61 -0.64 7.81e-42 Longevity; LIHC trans rs7246657 0.943 rs2303131 chr19:37936025 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs7903847 0.642 rs7074511 chr10:99140177 G/A cg06359132 chr10:99160096 RRP12 -0.41 -6.39 -0.33 5.47e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12477438 0.501 rs34272114 chr2:99737443 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs929354 0.557 rs62491947 chr7:156960813 G/A cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.8 0.5 1.31e-23 Colorectal cancer; LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.875 rs1564509 chr4:1236562 C/G cg19318889 chr4:1322082 MAEA 0.39 6.28 0.32 1.02e-9 Obesity-related traits; LIHC cis rs3736485 0.934 rs11635592 chr15:51859786 A/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs617791 0.508 rs747526 chr11:65776071 C/A cg17712092 chr4:129076599 LARP1B -0.56 -6.76 -0.34 5.92e-11 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27649522 chr12:12877729 APOLD1 0.42 6.35 0.32 6.93e-10 Pancreatic cancer; LIHC trans rs1005277 0.502 rs2800484 chr10:38542415 C/T cg23533926 chr12:111358616 MYL2 -0.36 -6.86 -0.35 3.18e-11 Extrinsic epigenetic age acceleration; LIHC cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg11644478 chr21:40555479 PSMG1 0.83 10.61 0.5 6.37e-23 Cognitive function; LIHC cis rs892961 0.932 rs7216909 chr17:75405234 A/G cg01320579 chr17:75405842 SEPT9 0.53 7.4 0.37 1.06e-12 Airflow obstruction; LIHC cis rs6960043 0.818 rs10487796 chr7:15063430 T/A cg19272540 chr7:15055459 NA 0.25 6.8 0.35 4.62e-11 Type 2 diabetes; LIHC trans rs208520 0.526 rs9294682 chr6:66795159 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.05 -20.66 -0.75 4.04e-62 Exhaled nitric oxide output; LIHC cis rs6930083 0.713 rs1321309 chr6:36638636 G/A cg08179530 chr6:36648295 CDKN1A -0.77 -13.02 -0.58 9.29e-32 Coronary artery disease; LIHC cis rs9911578 1.000 rs1057068 chr17:56598439 T/C cg12560992 chr17:57184187 TRIM37 -0.96 -17.35 -0.68 7.99e-49 Intelligence (multi-trait analysis); LIHC cis rs427394 1.000 rs182135 chr5:6747453 G/A cg10857441 chr5:6722123 POLS -0.35 -5.93 -0.31 7.32e-9 Menopause (age at onset); LIHC cis rs7582180 0.627 rs4149517 chr2:101014247 C/A cg14675211 chr2:100938903 LONRF2 0.55 8.11 0.4 9.12e-15 Intelligence (multi-trait analysis); LIHC cis rs17106184 0.892 rs76589723 chr1:51208574 G/A cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs365132 0.875 rs353496 chr5:176429898 T/C cg16309518 chr5:176445507 NA -0.53 -9.85 -0.47 2.53e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg21724239 chr8:58056113 NA 0.58 7.53 0.38 4.56e-13 Developmental language disorder (linguistic errors); LIHC cis rs10744422 0.843 rs3896870 chr12:123333611 T/C cg18912006 chr12:123335444 HIP1R -0.63 -7.51 -0.38 5.33e-13 Schizophrenia; LIHC cis rs2276314 0.947 rs3898595 chr18:33565885 T/A cg05985134 chr18:33552581 C18orf21 0.49 5.81 0.3 1.44e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs9816226 1.000 rs73052033 chr3:185828465 T/C cg00760338 chr3:185826511 ETV5 -0.71 -6.3 -0.32 9.09e-10 Obesity;Body mass index; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg20607798 chr8:58055168 NA 0.64 8.21 0.41 4.61e-15 Developmental language disorder (linguistic errors); LIHC cis rs7100689 0.599 rs6585968 chr10:82139807 T/C cg00277334 chr10:82204260 NA -0.57 -7.44 -0.37 8.36e-13 Post bronchodilator FEV1; LIHC cis rs5769765 0.632 rs13056783 chr22:50259152 A/T cg02269571 chr22:50332266 NA 0.6 8.45 0.42 8.41e-16 Schizophrenia; LIHC cis rs9790314 0.631 rs2061804 chr3:161102474 C/A cg17135325 chr3:160939158 NMD3 0.45 6.86 0.35 3.25e-11 Morning vs. evening chronotype; LIHC trans rs877282 0.898 rs11253356 chr10:768604 G/A cg22713356 chr15:30763199 NA 1.17 11.34 0.52 1.61e-25 Uric acid levels; LIHC cis rs9560113 1.000 rs9560110 chr13:112181233 C/T cg14154082 chr13:112174009 NA 0.3 6.39 0.33 5.52e-10 Menarche (age at onset); LIHC cis rs2180341 0.883 rs7760748 chr6:127690062 C/T cg27446573 chr6:127587934 RNF146 1.0 15.51 0.64 1.82e-41 Breast cancer; LIHC cis rs6456156 0.565 rs6456153 chr6:167472167 T/C cg07741184 chr6:167504864 NA 0.29 6.86 0.35 3.3e-11 Primary biliary cholangitis; LIHC cis rs870825 0.616 rs2141258 chr4:185609576 A/C cg04058563 chr4:185651563 MLF1IP -0.54 -5.98 -0.31 5.78e-9 Blood protein levels; LIHC cis rs1008375 0.898 rs4698623 chr4:17594702 T/C cg16339924 chr4:17578868 LAP3 0.45 6.32 0.32 8.17e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12477438 0.520 rs2171359 chr2:99795360 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.21 0.61 2.47e-36 Chronic sinus infection; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg07677032 chr17:61819896 STRADA 0.42 6.27 0.32 1.06e-9 Prudent dietary pattern; LIHC cis rs67311347 1.000 rs4974017 chr3:40473519 C/T cg00656387 chr3:40428638 ENTPD3 0.44 7.45 0.37 7.71e-13 Renal cell carcinoma; LIHC cis rs35110281 0.633 rs4818860 chr21:45119617 C/T cg21573476 chr21:45109991 RRP1B -0.53 -10.45 -0.49 2.28e-22 Mean corpuscular volume; LIHC cis rs7772486 0.790 rs6923545 chr6:146244743 A/G cg13319975 chr6:146136371 FBXO30 0.38 6.07 0.31 3.46e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs11552708 0.504 rs8082166 chr17:7388728 G/C cg08566640 chr11:64091735 NA -0.67 -6.13 -0.31 2.36e-9 IgM levels; LIHC cis rs10540 1.000 rs61876334 chr11:487201 T/C cg03576123 chr11:487126 PTDSS2 -1.01 -7.81 -0.39 7.07e-14 Body mass index; LIHC cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs35883536 0.626 rs7545966 chr1:101047633 G/A cg14515779 chr1:101123966 NA 0.49 6.76 0.34 6e-11 Monocyte count; LIHC cis rs9818758 0.607 rs11719220 chr3:49245201 A/G cg07636037 chr3:49044803 WDR6 -0.82 -8.43 -0.41 1e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg25894440 chr7:65020034 NA 0.55 6.21 0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs2292096 0.866 rs35796457 chr1:200696601 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.45 -6.03 -0.31 4.24e-9 Epilepsy; LIHC cis rs7904368 0.806 rs7087360 chr10:16872337 C/A cg14835575 chr10:16859367 RSU1 0.48 7.34 0.37 1.59e-12 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs10883723 0.810 rs6584504 chr10:104253507 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4654899 0.965 rs4654898 chr1:21376383 T/C cg08539965 chr1:21396338 EIF4G3 0.33 5.72 0.3 2.3e-8 Superior frontal gyrus grey matter volume; LIHC cis rs61990749 0.544 rs176962 chr14:78185510 T/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.77 -0.39 9.19e-14 Fibroblast growth factor basic levels; LIHC cis rs7208859 0.673 rs9891179 chr17:29208160 G/T cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10193935 1.000 rs12622910 chr2:42398918 C/A cg27598129 chr2:42591480 NA -0.75 -11.51 -0.53 3.86e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs79149102 0.579 rs7166105 chr15:75343942 A/G cg09165964 chr15:75287851 SCAMP5 0.61 8.02 0.4 1.66e-14 Lung cancer; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs727505 0.954 rs28638102 chr7:124499480 A/C cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.1e-9 Lewy body disease; LIHC cis rs9393692 0.905 rs7746807 chr6:26293338 C/A cg05868516 chr6:26286170 HIST1H4H 0.4 5.97 0.31 6.08e-9 Educational attainment; LIHC cis rs2439831 0.850 rs7169988 chr15:44060435 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.36 0.41 1.61e-15 Lung cancer in ever smokers; LIHC cis rs17345786 0.511 rs12639028 chr3:101346033 G/C cg12386194 chr3:101231763 SENP7 0.41 6.26 0.32 1.17e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs3741404 0.594 rs11231704 chr11:63898182 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.59 -7.42 -0.37 9.22e-13 Platelet count; LIHC cis rs1144333 0.655 rs114383686 chr1:76325327 C/T cg03433033 chr1:76189801 ACADM 0.58 8.65 0.42 1.97e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs8017423 0.935 rs8012299 chr14:90715822 G/T cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 3.09e-9 Mortality in heart failure; LIHC cis rs9611565 0.694 rs5758411 chr22:42079734 G/A cg03806693 chr22:41940476 POLR3H 0.8 9.09 0.44 8.24e-18 Vitiligo; LIHC cis rs3540 0.554 rs12900987 chr15:91071776 T/C cg22089800 chr15:90895588 ZNF774 -0.56 -7.74 -0.39 1.15e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs6952808 0.792 rs12536261 chr7:1953571 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.26 -0.45 2.23e-18 Bipolar disorder and schizophrenia; LIHC cis rs7395581 0.797 rs10838681 chr11:47275064 C/T cg25783544 chr11:47291846 MADD 0.44 6.31 0.32 8.58e-10 HDL cholesterol; LIHC cis rs1475911 0.708 rs66994219 chr21:43521647 G/A cg19766460 chr21:43528205 UMODL1;C21orf128 1.17 19.76 0.73 1.67e-58 IgG glycosylation; LIHC cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg27170947 chr2:26402098 FAM59B 0.62 6.52 0.33 2.57e-10 Gut microbiome composition (summer); LIHC cis rs507080 0.733 rs517445 chr11:118573535 A/G cg04173919 chr11:118528438 PHLDB1 0.32 6.02 0.31 4.44e-9 Serum metabolite levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13629201 chr9:5111420 JAK2 0.4 6.15 0.32 2.11e-9 Longevity; LIHC cis rs7267979 1.000 rs2257985 chr20:25269743 G/T cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs2932538 0.922 rs17438324 chr1:113100573 C/T cg22162597 chr1:113214053 CAPZA1 0.7 10.72 0.5 2.69e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7618501 0.699 rs2681781 chr3:49898273 A/G cg24110177 chr3:50126178 RBM5 -0.53 -8.22 -0.41 4.25e-15 Intelligence (multi-trait analysis); LIHC cis rs2573652 0.722 rs12898366 chr15:100543067 C/T cg09918751 chr15:100517450 ADAMTS17 -0.7 -12.34 -0.56 3.35e-29 Height; LIHC cis rs17376456 0.877 rs10061080 chr5:93420559 A/G cg25358565 chr5:93447407 FAM172A 1.13 10.46 0.49 2.1e-22 Diabetic retinopathy; LIHC cis rs7208859 0.573 rs73267873 chr17:29068457 C/T cg14067834 chr17:29058358 SUZ12P 0.69 7.14 0.36 5.51e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2439831 1.000 rs2245908 chr15:43731454 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.67 0.59 3.13e-34 Lung cancer in ever smokers; LIHC cis rs11718455 0.585 rs1491708 chr3:43911578 C/T cg08738300 chr3:44038990 NA 0.37 6.26 0.32 1.17e-9 Coronary artery disease; LIHC cis rs1577917 1.000 rs1337844 chr6:86677273 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.06 -0.48 5.08e-21 Response to antipsychotic treatment; LIHC cis rs6570726 0.791 rs392612 chr6:145881586 C/G cg13319975 chr6:146136371 FBXO30 0.38 6.3 0.32 9.32e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs13392177 0.684 rs6720105 chr2:219080718 G/A cg00012203 chr2:219082015 ARPC2 -0.75 -11.33 -0.52 1.8e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC trans rs17288586 1.000 rs17288586 chr6:45819770 C/T cg03694391 chr13:111100098 COL4A2 0.31 6.15 0.32 2.22e-9 Response to paliperidone in schizophrenia (CGI-S score); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01365452 chr4:7043077 CCDC96 0.47 6.92 0.35 2.3e-11 Pancreatic cancer; LIHC cis rs17818399 0.547 rs4953400 chr2:46777208 T/A cg02822958 chr2:46747628 ATP6V1E2 0.45 6.33 0.32 7.81e-10 Height; LIHC cis rs1029738 0.500 rs13227539 chr7:22884156 C/G cg11367502 chr7:22862612 TOMM7 -0.36 -6.07 -0.31 3.41e-9 Fibrinogen levels; LIHC cis rs17253792 0.915 rs79100824 chr14:56179606 C/T cg01858014 chr14:56050164 KTN1 -0.75 -7.41 -0.37 9.7e-13 Putamen volume; LIHC cis rs10170846 0.893 rs12614976 chr2:223542896 A/T cg25565276 chr2:223520875 FARSB 0.64 9.52 0.46 3.37e-19 Schizophrenia (inflammation and infection response interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20824237 chr3:99979579 TBC1D23 0.43 6.05 0.31 3.76e-9 Pancreatic cancer; LIHC cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg21016266 chr12:122356598 WDR66 0.52 7.6 0.38 2.94e-13 Mean corpuscular volume; LIHC cis rs5769765 0.908 rs138866 chr22:50205903 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.65 7.84 0.39 5.61e-14 Schizophrenia; LIHC cis rs1577917 0.655 rs7766485 chr6:86263555 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.45 0.42 8.29e-16 Response to antipsychotic treatment; LIHC cis rs5769765 1.000 rs8184990 chr22:50273174 A/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs644148 0.967 rs2686778 chr19:44972257 G/A cg15540054 chr19:45004280 ZNF180 -0.77 -11.42 -0.53 8.6e-26 Personality dimensions; LIHC cis rs782590 0.967 rs62165172 chr2:55736237 A/G cg03859395 chr2:55845619 SMEK2 0.92 16.06 0.66 1.2e-43 Metabolic syndrome; LIHC cis rs1577917 1.000 rs10944170 chr6:86685469 A/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.4 -0.33 5.09e-10 Response to antipsychotic treatment; LIHC trans rs9940464 0.901 rs4782770 chr16:83362689 C/G cg02755603 chr20:18548475 LOC388789 0.35 6.17 0.32 1.95e-9 Malaria; LIHC cis rs7937682 1.000 rs4936661 chr11:111587495 G/A cg09085632 chr11:111637200 PPP2R1B 1.11 15.85 0.65 8.47e-43 Primary sclerosing cholangitis; LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg00091569 chr3:40428383 ENTPD3 0.41 6.97 0.35 1.67e-11 Renal cell carcinoma; LIHC cis rs2635047 0.875 rs2635040 chr18:44640972 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.48 6.27 0.32 1.08e-9 Educational attainment; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05262316 chr6:64345491 NA 0.38 6.22 0.32 1.47e-9 Pancreatic cancer; LIHC cis rs9980664 1.000 rs9980664 chr21:34734510 G/T cg04842828 chr21:34696676 IFNAR1 0.46 6.06 0.31 3.57e-9 Cognitive decline (age-related); LIHC trans rs208520 0.742 rs208454 chr6:66907783 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.71 -7.65 -0.38 2.05e-13 Exhaled nitric oxide output; LIHC cis rs1144333 0.655 rs58722308 chr1:76423525 A/G cg22875332 chr1:76189707 ACADM 0.4 6.06 0.31 3.51e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05464172 chr8:97247954 UQCRB 0.44 7.13 0.36 6.06e-12 Cognitive function; LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.21e-14 Prudent dietary pattern; LIHC cis rs546131 0.928 rs499183 chr11:34836678 A/G cg11058730 chr11:34937778 PDHX;APIP 0.6 9.29 0.45 1.91e-18 Lung disease severity in cystic fibrosis; LIHC cis rs6570726 0.902 rs373321 chr6:145854150 T/A cg23711669 chr6:146136114 FBXO30 0.56 10.03 0.48 6.55e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504073 0.647 rs56057508 chr8:49982793 G/T cg00325661 chr8:49890786 NA 0.34 7.96 0.4 2.59e-14 Blood metabolite ratios; LIHC trans rs17685 0.664 rs9801113 chr7:75792031 C/T cg19862616 chr7:65841803 NCRNA00174 0.94 19.23 0.72 2.29e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs743757 1.000 rs2282752 chr3:50433967 G/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.48 6.78 0.34 5.2e-11 Diastolic blood pressure; LIHC cis rs4819052 0.851 rs875621 chr21:46682295 A/G cg22633049 chr21:46681294 NA -0.36 -6.18 -0.32 1.87e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20080320 chr15:28363860 HERC2 -0.42 -6.73 -0.34 6.97e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg23172400 chr8:95962367 TP53INP1 0.35 7.9 0.39 3.85e-14 Type 2 diabetes; LIHC cis rs9837602 0.529 rs793494 chr3:99508768 T/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.42 -6.01 -0.31 4.67e-9 Breast cancer; LIHC cis rs763014 0.966 rs12935215 chr16:670605 T/C cg00908189 chr16:619842 PIGQ 0.83 13.13 0.58 3.52e-32 Height; LIHC cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 11.65 0.53 1.26e-26 Alzheimer's disease; LIHC cis rs798554 0.723 rs798518 chr7:2777825 A/G cg13628971 chr7:2884303 GNA12 0.54 8.08 0.4 1.14e-14 Height; LIHC cis rs4665809 1.000 rs10202478 chr2:26276049 T/C cg27170947 chr2:26402098 FAM59B -0.66 -8.22 -0.41 4.16e-15 Gut microbiome composition (summer); LIHC cis rs9359856 0.636 rs3748085 chr6:90315789 C/T cg13799429 chr6:90582589 CASP8AP2 -0.61 -6.81 -0.35 4.4e-11 Bipolar disorder; LIHC cis rs6500602 0.673 rs4786513 chr16:4576423 T/C cg08645402 chr16:4508243 NA 0.39 7.24 0.36 3.03e-12 Schizophrenia; LIHC cis rs9916302 0.851 rs7220650 chr17:37487168 A/G cg00129232 chr17:37814104 STARD3 0.38 6.06 0.31 3.69e-9 Glomerular filtration rate (creatinine); LIHC cis rs75908454 1.000 rs80114444 chr6:169939774 G/A cg19338460 chr6:170058176 WDR27 -0.8 -7.47 -0.37 6.58e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs35955747 0.902 rs131202 chr22:31709309 A/C cg22777020 chr22:31556080 RNF185 0.5 5.89 0.3 9.22e-9 Neutrophil count;Sum basophil neutrophil counts; LIHC cis rs74417235 0.528 rs9324789 chr5:154074362 C/T cg19735590 chr5:154026979 NA -0.51 -5.99 -0.31 5.3e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs35883536 0.647 rs7524322 chr1:101047730 C/G cg14515779 chr1:101123966 NA -0.47 -6.53 -0.33 2.41e-10 Monocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24783322 chr8:49834643 SNAI2 0.44 6.14 0.32 2.25e-9 Pancreatic cancer; LIHC cis rs11608355 0.515 rs11614551 chr12:109931630 G/A cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs826838 0.868 rs12322306 chr12:39130021 A/G cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs875971 1.000 rs778710 chr7:65854834 T/C cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs9733 0.596 rs34140753 chr1:150642583 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs2842992 0.789 rs7765490 chr6:160204326 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.68 12.02 0.54 5.41e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs523522 0.962 rs3742052 chr12:120966921 A/G cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg18279126 chr7:2041391 MAD1L1 0.39 6.56 0.33 2.04e-10 Bipolar disorder and schizophrenia; LIHC cis rs2806561 0.828 rs944509 chr1:23542242 C/T cg19743168 chr1:23544995 NA -0.39 -7.19 -0.36 4.18e-12 Height; LIHC cis rs3862030 0.720 rs11595149 chr10:104235978 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -7.2 -0.36 3.88e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs8180040 0.726 rs2305638 chr3:47046842 G/C cg16586182 chr3:47516702 SCAP -0.5 -9.14 -0.44 5.5e-18 Colorectal cancer; LIHC cis rs10752881 1.000 rs8179282 chr1:182974598 C/G ch.1.3577855R chr1:183094577 LAMC1 0.58 9.86 0.47 2.39e-20 Colorectal cancer; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg23411876 chr7:140396886 LOC100134713;NDUFB2 0.47 6.84 0.35 3.6e-11 Alopecia areata; LIHC trans rs6600671 0.934 rs7528274 chr1:121286901 A/T cg09829573 chr1:144692074 NBPF9 -0.41 -7.33 -0.37 1.69e-12 Hip geometry; LIHC cis rs2412488 0.893 rs4864767 chr4:54367136 G/A cg22241045 chr4:54363911 LNX1 0.44 7.38 0.37 1.24e-12 DNA methylation (variation); LIHC cis rs7903847 0.667 rs11189181 chr10:99144154 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.65 -0.34 1.15e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1005277 0.579 rs2504143 chr10:38383706 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg11062466 chr8:58055876 NA 0.49 7.11 0.36 6.72e-12 Developmental language disorder (linguistic errors); LIHC cis rs8062405 0.755 rs12447461 chr16:28582941 C/A cg00204512 chr16:28754710 NA 0.4 7.01 0.35 1.24e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs875971 0.862 rs1875057 chr7:65731855 A/G cg11764359 chr7:65958608 NA -0.77 -13.25 -0.58 1.25e-32 Aortic root size; LIHC cis rs13191362 1.000 rs13215491 chr6:163010325 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7251275 0.744 rs17655646 chr19:44134936 G/A cg17121205 chr19:44009353 PHLDB3 0.4 5.94 0.31 7.16e-9 Macrophage inflammatory protein 1b levels; LIHC cis rs3106136 0.933 rs35718240 chr4:95164030 G/A cg11021082 chr4:95130006 SMARCAD1 -0.35 -6.44 -0.33 4.11e-10 Capecitabine sensitivity; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs12908161 1.000 rs12908161 chr15:85207825 A/G cg12863693 chr15:85201151 NMB 0.49 6.93 0.35 2.12e-11 Schizophrenia; LIHC cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg09913183 chr17:42254507 C17orf65;ASB16 0.68 10.57 0.5 8.64e-23 Total body bone mineral density; LIHC cis rs853679 0.542 rs9380063 chr6:28137853 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs7119038 0.779 rs73005502 chr11:118697906 A/G cg19308663 chr11:118741387 NA 0.44 5.75 0.3 2.02e-8 Sjögren's syndrome; LIHC cis rs11711311 0.955 rs7650764 chr3:113414439 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.35 -6.5 -0.33 2.89e-10 IgG glycosylation; LIHC cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC cis rs7647973 1.000 rs1464569 chr3:49460350 A/G cg07636037 chr3:49044803 WDR6 0.52 6.58 0.34 1.72e-10 Menarche (age at onset); LIHC cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg06882758 chr19:58662330 ZNF329 0.93 6.97 0.35 1.6e-11 Cholesterol, total; LIHC cis rs7772486 0.790 rs9403749 chr6:146162239 A/G cg23711669 chr6:146136114 FBXO30 0.74 13.54 0.59 9.65e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs1580019 0.587 rs9638880 chr7:32552401 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.17 0.32 1.89e-9 Cognitive ability; LIHC cis rs57502260 0.834 rs3736228 chr11:68201295 A/G cg01657329 chr11:68192670 LRP5 0.53 6.01 0.31 4.85e-9 Total body bone mineral density (age 45-60); LIHC cis rs9394841 0.692 rs9381094 chr6:41800629 T/C cg08135965 chr6:41755394 TOMM6 0.46 6.13 0.31 2.41e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs798554 0.757 rs1182177 chr7:2874540 C/T cg19717773 chr7:2847554 GNA12 -0.42 -6.32 -0.32 8.1e-10 Height; LIHC cis rs2980439 0.556 rs2921059 chr8:8317887 G/T cg06636001 chr8:8085503 FLJ10661 0.7 11.19 0.52 5.5e-25 Neuroticism; LIHC cis rs921968 0.643 rs508157 chr2:219435288 G/A cg02985541 chr2:219472218 PLCD4 0.44 8.29 0.41 2.53e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs6754311 0.731 rs309164 chr2:136691825 T/C cg25344623 chr2:136566232 LCT -0.36 -7.34 -0.37 1.6e-12 Mosquito bite size; LIHC cis rs929354 0.772 rs1182448 chr7:157021415 G/A cg17757837 chr7:157058334 UBE3C -0.73 -11.93 -0.54 1.12e-27 Body mass index; LIHC cis rs9612 1.000 rs346526 chr19:44259565 A/G cg08581076 chr19:44259116 C19orf61 0.7 8.94 0.44 2.49e-17 Exhaled nitric oxide output; LIHC cis rs9814567 1.000 rs6801596 chr3:134252114 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2404602 0.716 rs2164101 chr15:76749117 A/G cg23625390 chr15:77176239 SCAPER 0.37 6.14 0.31 2.35e-9 Blood metabolite levels; LIHC cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg13271783 chr10:134563150 INPP5A -0.57 -6.63 -0.34 1.32e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9325144 0.602 rs10785590 chr12:38694145 C/T cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.42e-14 Morning vs. evening chronotype; LIHC cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 -0.98 -9.72 -0.47 6.81e-20 Platelet count; LIHC cis rs2629540 0.847 rs12762597 chr10:126387043 G/A cg08799069 chr10:126477246 METTL10 0.47 7.4 0.37 1.07e-12 Cocaine dependence; LIHC cis rs11252926 0.574 rs10904065 chr10:423226 G/T cg16346588 chr10:242978 ZMYND11 -0.5 -5.88 -0.3 9.83e-9 Psychosis in Alzheimer's disease; LIHC cis rs7666738 0.546 rs9993299 chr4:98815976 G/A cg05340658 chr4:99064831 C4orf37 0.49 6.35 0.32 7.03e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs6442522 0.560 rs7631005 chr3:15515061 C/T cg16303742 chr3:15540471 COLQ 0.36 5.9 0.3 8.58e-9 Uric acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03065641 chr8:145133200 EXOSC4 0.51 7.42 0.37 9.38e-13 Pancreatic cancer; LIHC cis rs700651 0.789 rs62277902 chr2:198879443 T/A cg00792783 chr2:198669748 PLCL1 -0.41 -5.94 -0.31 7.02e-9 Intracranial aneurysm; LIHC cis rs7927592 0.913 rs2282563 chr11:68333200 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.25 -0.32 1.24e-9 Total body bone mineral density; LIHC cis rs6831352 0.819 rs1154401 chr4:100009738 G/C cg12011299 chr4:100065546 ADH4 0.56 10.05 0.48 5.41e-21 Alcohol dependence; LIHC cis rs17685 0.753 rs869804 chr7:75688954 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.47 -0.33 3.42e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1580019 0.523 rs9791770 chr7:32582252 C/A cg07520158 chr7:32535189 LSM5;AVL9 0.61 9.02 0.44 1.37e-17 Cognitive ability; LIHC cis rs2439831 0.850 rs28590651 chr15:44113016 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.58 7.96 0.4 2.55e-14 Lung cancer in ever smokers; LIHC cis rs9918079 0.506 rs7696127 chr4:15642953 T/A cg16509355 chr4:15471240 CC2D2A -0.46 -7.12 -0.36 6.56e-12 Obesity-related traits; LIHC cis rs2180341 0.782 rs6912006 chr6:127722631 C/T cg24812749 chr6:127587940 RNF146 0.66 10.35 0.49 5.03e-22 Breast cancer; LIHC cis rs10193935 0.901 rs10200000 chr2:42442212 A/G cg27598129 chr2:42591480 NA -0.73 -11.39 -0.52 1.11e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg08888203 chr3:10149979 C3orf24 0.53 6.36 0.33 6.62e-10 Alzheimer's disease; LIHC cis rs1552244 0.554 rs34391585 chr3:9999208 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.81 0.39 6.86e-14 Alzheimer's disease; LIHC cis rs763121 0.626 rs5750643 chr22:39009017 A/G cg14440974 chr22:39074834 NA -0.35 -5.88 -0.3 9.63e-9 Menopause (age at onset); LIHC cis rs9399135 0.933 rs4559100 chr6:135324085 T/C cg24558204 chr6:135376177 HBS1L 0.4 6.65 0.34 1.15e-10 Red blood cell count; LIHC cis rs782590 0.537 rs12619903 chr2:55884106 T/A cg03859395 chr2:55845619 SMEK2 -0.48 -7.62 -0.38 2.46e-13 Metabolic syndrome; LIHC cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.46e-8 Menopause (age at onset); LIHC cis rs10792665 0.698 rs948184 chr11:82722659 G/A cg24227371 chr11:82718527 RAB30 -0.38 -9.3 -0.45 1.69e-18 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09983252 chr4:119555556 NA 0.38 6.24 0.32 1.28e-9 Pancreatic cancer; LIHC cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg06481639 chr22:41940642 POLR3H 0.7 7.03 0.36 1.16e-11 Vitiligo; LIHC cis rs4700695 0.925 rs12653007 chr5:65396965 G/A cg21114390 chr5:65439923 SFRS12 -0.5 -6.92 -0.35 2.24e-11 Facial morphology (factor 19); LIHC cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.73 0.57 1.2e-30 Alzheimer's disease; LIHC cis rs6539247 0.527 rs10778456 chr12:106448302 C/T cg20883310 chr12:106464547 NUAK1 0.42 6.72 0.34 7.75e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs2120019 1.000 rs7162900 chr15:75368017 T/C cg17294928 chr15:75287854 SCAMP5 -0.52 -8.14 -0.4 7.6e-15 Blood trace element (Zn levels); LIHC cis rs7546668 1.000 rs3795758 chr1:15853551 C/T cg11706911 chr1:15910989 AGMAT 0.44 6.83 0.35 3.91e-11 Glomerular filtration rate (creatinine); LIHC trans rs61931739 0.534 rs11053075 chr12:34207009 A/G cg26384229 chr12:38710491 ALG10B -0.54 -6.98 -0.35 1.51e-11 Morning vs. evening chronotype; LIHC cis rs2842992 0.789 rs4276525 chr6:160193612 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.5 8.78 0.43 8.08e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs965469 0.846 rs7271575 chr20:3333877 C/T cg25506879 chr20:3388711 C20orf194 -0.57 -6.88 -0.35 2.95e-11 IFN-related cytopenia; LIHC cis rs4819052 1.000 rs3746980 chr21:46711580 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 10.47 0.49 1.88e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1046896 0.520 rs8074086 chr17:80818460 A/C cg02711726 chr17:80685570 FN3KRP -0.45 -8.29 -0.41 2.65e-15 Glycated hemoglobin levels; LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg02290350 chr8:58132656 NA 0.51 11.03 0.51 2.11e-24 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.875 rs1125461 chr6:146417653 C/T cg23711669 chr6:146136114 FBXO30 0.66 11.22 0.52 4.41e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs921968 0.643 rs539451 chr2:219426972 T/C cg18887096 chr2:219472410 PLCD4 0.37 6.43 0.33 4.28e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2282802 0.651 rs10060071 chr5:139599097 T/C cg26211634 chr5:139558579 C5orf32 0.39 6.14 0.31 2.33e-9 Intelligence (multi-trait analysis); LIHC cis rs4700695 1.000 rs12518359 chr5:65397909 T/C cg21114390 chr5:65439923 SFRS12 -0.5 -6.92 -0.35 2.3e-11 Facial morphology (factor 19); LIHC cis rs2075371 0.829 rs11770521 chr7:133936251 A/C cg20476274 chr7:133979776 SLC35B4 0.67 9.23 0.45 2.8e-18 Mean platelet volume; LIHC cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg22168489 chr12:122356033 WDR66 0.38 6.16 0.32 2.07e-9 Mean corpuscular volume; LIHC cis rs986417 0.818 rs767602 chr14:61098624 G/T cg27398547 chr14:60952738 C14orf39 0.59 6.19 0.32 1.71e-9 Gut microbiota (bacterial taxa); LIHC cis rs243505 0.559 rs10215794 chr7:148478895 C/G cg09806900 chr7:148480153 CUL1 0.42 6.19 0.32 1.76e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1348850 0.526 rs7582179 chr2:178370631 A/G cg27490568 chr2:178487706 NA 1.0 11.19 0.52 5.68e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs263063 0.920 rs4807681 chr19:5037764 T/C cg18473234 chr19:5097819 KDM4B -0.55 -6.86 -0.35 3.19e-11 Periodontitis (CDC/AAP); LIHC cis rs2012796 0.785 rs61986597 chr14:81853107 T/C cg02996355 chr14:81879375 NA 0.79 12.82 0.57 5.31e-31 Night sleep phenotypes; LIHC cis rs6942756 0.758 rs13226649 chr7:128977598 C/T cg02491457 chr7:128862824 NA -0.56 -8.33 -0.41 2.05e-15 White matter hyperintensity burden; LIHC cis rs6570726 0.599 rs9403725 chr6:145897622 A/T cg05347473 chr6:146136440 FBXO30 -0.45 -6.36 -0.33 6.48e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs61931739 0.534 rs4931783 chr12:34115322 G/A cg26384229 chr12:38710491 ALG10B 0.53 7.23 0.36 3.27e-12 Morning vs. evening chronotype; LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg16034541 chr3:195490309 MUC4 0.63 9.95 0.47 1.14e-20 Lung disease severity in cystic fibrosis; LIHC cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg18357526 chr6:26021779 HIST1H4A 0.7 8.97 0.44 1.92e-17 Urate levels; LIHC cis rs992157 0.866 rs2292554 chr2:219146868 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.16 -0.55 1.65e-28 Colorectal cancer; LIHC cis rs924607 0.966 rs1621827 chr5:635074 A/G cg04221910 chr5:616842 CEP72 0.41 7.33 0.37 1.63e-12 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs8027181 0.839 rs998020 chr15:72999635 C/T cg25632853 chr15:73088954 NA 0.37 6.14 0.32 2.31e-9 Triglyceride levels; LIHC trans rs12310956 0.532 rs10844707 chr12:33936089 T/C cg26384229 chr12:38710491 ALG10B 0.52 7.35 0.37 1.49e-12 Morning vs. evening chronotype; LIHC cis rs2737618 0.674 rs2737683 chr1:200092448 G/A cg21825944 chr1:200113062 NR5A2 -0.48 -8.07 -0.4 1.22e-14 Uric acid levels; LIHC cis rs7568458 0.709 rs11895401 chr2:85753847 C/T cg02493740 chr2:85810744 VAMP5 -0.45 -7.58 -0.38 3.19e-13 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7264396 0.563 rs6060560 chr20:34278890 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.6 -8.23 -0.41 4.01e-15 Total cholesterol levels; LIHC cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg09455208 chr3:40491958 NA 0.36 7.2 0.36 3.94e-12 Renal cell carcinoma; LIHC cis rs477692 0.648 rs10829603 chr10:131327351 T/G cg19680672 chr10:131412579 MGMT -0.39 -5.96 -0.31 6.43e-9 Response to temozolomide; LIHC cis rs2242116 0.727 rs10865943 chr3:46969970 T/C cg23352942 chr3:46931381 PTH1R -0.28 -7.21 -0.36 3.61e-12 Birth weight; LIHC cis rs847649 0.842 rs1608651 chr7:102624192 C/T cg18108683 chr7:102477205 FBXL13 0.48 7.13 0.36 6.11e-12 Morning vs. evening chronotype; LIHC cis rs9818758 0.607 rs9837237 chr3:49215583 G/T cg00383909 chr3:49044727 WDR6 0.89 7.37 0.37 1.33e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9611565 0.592 rs1811113 chr22:42073134 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.56 0.5 9.87e-23 Vitiligo; LIHC cis rs11098499 0.648 rs2002047 chr4:120257228 A/G cg09307838 chr4:120376055 NA 0.7 11.05 0.51 1.72e-24 Corneal astigmatism; LIHC cis rs2235573 0.527 rs139866 chr22:38354684 C/T cg03989125 chr22:38214979 NA -0.43 -5.97 -0.31 5.97e-9 Glioblastoma;Glioma; LIHC cis rs2153535 0.580 rs2184583 chr6:8447808 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs7552404 0.590 rs1565717 chr1:76320441 T/C cg10523679 chr1:76189770 ACADM -0.55 -6.9 -0.35 2.48e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10779751 1.000 rs7526649 chr1:11278163 C/T cg08854313 chr1:11322531 MTOR 0.79 11.2 0.52 4.97e-25 Body mass index; LIHC cis rs1348850 0.914 rs7587604 chr2:178309848 T/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.14 0.58 3.31e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs611744 0.967 rs597992 chr8:109193808 A/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs1949733 0.701 rs871768 chr4:8454938 G/A cg11789530 chr4:8429930 ACOX3 0.76 11.05 0.51 1.81e-24 Response to antineoplastic agents; LIHC cis rs1843834 0.611 rs1058360 chr2:225449242 A/T cg22509189 chr2:225307070 NA -0.82 -11.55 -0.53 2.74e-26 IgE levels in asthmatics (D.p. specific); LIHC cis rs7937682 0.921 rs10891280 chr11:111433609 A/T cg09085632 chr11:111637200 PPP2R1B 0.81 9.2 0.45 3.64e-18 Primary sclerosing cholangitis; LIHC cis rs7872515 0.838 rs7860518 chr9:94826465 C/T cg01248375 chr9:94877805 SPTLC1 0.53 7.55 0.38 4.1e-13 Bipolar disorder and schizophrenia; LIHC cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg20607798 chr8:58055168 NA 0.49 6.13 0.31 2.37e-9 Developmental language disorder (linguistic errors); LIHC cis rs3736485 0.934 rs28648597 chr15:51856066 T/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7193541 0.691 rs3851728 chr16:74480660 C/T cg01733217 chr16:74700730 RFWD3 0.45 8.24 0.41 3.71e-15 Multiple myeloma; LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg19550733 chr1:25869992 LDLRAP1 -0.47 -6.1 -0.31 2.86e-9 Thyroid stimulating hormone; LIHC cis rs35306767 0.953 rs11253521 chr10:976416 G/C cg25019033 chr10:957182 NA -0.4 -5.74 -0.3 2.15e-8 Eosinophil percentage of granulocytes; LIHC cis rs9549328 0.756 rs2993291 chr13:113653846 C/T cg08528486 chr13:113648767 MCF2L -0.4 -6.31 -0.32 8.41e-10 Systolic blood pressure; LIHC cis rs9733 0.596 rs72702557 chr1:150680130 A/G cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs986417 1.000 rs1254302 chr14:60885343 A/C cg27398547 chr14:60952738 C14orf39 -0.74 -8.61 -0.42 2.67e-16 Gut microbiota (bacterial taxa); LIHC cis rs807669 0.772 rs809901 chr22:19228736 C/T cg02655711 chr22:19163373 SLC25A1 0.38 7.12 0.36 6.6e-12 Metabolite levels; LIHC cis rs4822044 0.560 rs7284839 chr22:42010902 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.69 0.5 3.46e-23 Cannabis dependence symptom count; LIHC cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg06453172 chr10:134556979 INPP5A -0.61 -8.38 -0.41 1.4e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs34375054 0.525 rs7133006 chr12:125606123 G/A cg25124228 chr12:125621409 AACS -0.5 -9.36 -0.45 1.12e-18 Post bronchodilator FEV1/FVC ratio; LIHC cis rs3770081 1.000 rs57398459 chr2:86291326 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -8.49 -0.42 6.21e-16 Facial emotion recognition (sad faces); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10909163 chr13:41635251 WBP4 0.41 6.16 0.32 2.02e-9 Lung function (FEV1/FVC); LIHC cis rs9640161 0.789 rs1464752 chr7:150021284 C/T cg10018233 chr7:150070692 REPIN1 0.57 9.68 0.46 9.89e-20 Blood protein levels;Circulating chemerin levels; LIHC cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg08888203 chr3:10149979 C3orf24 0.61 6.65 0.34 1.17e-10 Alzheimer's disease; LIHC cis rs9457247 0.565 rs2038580 chr6:167456490 A/T cg07741184 chr6:167504864 NA 0.34 7.72 0.39 1.3e-13 Crohn's disease; LIHC cis rs9911578 1.000 rs1472288 chr17:56910720 G/A cg05425664 chr17:57184151 TRIM37 -0.59 -8.83 -0.43 5.44e-17 Intelligence (multi-trait analysis); LIHC cis rs644799 1.000 rs560854 chr11:95584905 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.66 9.31 0.45 1.53e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg00656387 chr3:40428638 ENTPD3 0.42 6.83 0.35 4.01e-11 Renal cell carcinoma; LIHC trans rs9291683 0.575 rs3756223 chr4:10105797 C/T cg26043149 chr18:55253948 FECH 0.38 6.04 0.31 3.96e-9 Bone mineral density; LIHC cis rs11792861 0.926 rs72607166 chr9:111821530 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.84 0.43 5.31e-17 Menarche (age at onset); LIHC cis rs6570726 0.875 rs12524077 chr6:145866333 G/C cg23711669 chr6:146136114 FBXO30 0.56 10.02 0.48 7.09e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs2576037 0.583 rs12386118 chr18:44540376 C/G cg19077165 chr18:44547161 KATNAL2 -0.48 -7.26 -0.37 2.62e-12 Personality dimensions; LIHC cis rs2153535 0.601 rs9393030 chr6:8516489 C/G cg07606381 chr6:8435919 SLC35B3 0.8 11.94 0.54 1.07e-27 Motion sickness; LIHC trans rs2727020 0.894 rs3862342 chr11:49357043 C/T cg15704280 chr7:45808275 SEPT13 -0.74 -11.1 -0.51 1.19e-24 Coronary artery disease; LIHC cis rs7582180 0.607 rs6725052 chr2:100935817 G/A cg14675211 chr2:100938903 LONRF2 0.56 8.8 0.43 6.83e-17 Intelligence (multi-trait analysis); LIHC cis rs4728302 0.869 rs6955240 chr7:133581873 G/A cg10665199 chr7:133106180 EXOC4 0.35 6.2 0.32 1.63e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs6977660 0.714 rs10231980 chr7:19789383 C/G cg07541023 chr7:19748670 TWISTNB 0.47 6.97 0.35 1.65e-11 Thyroid stimulating hormone; LIHC cis rs9790314 0.875 rs55688744 chr3:160944222 G/A cg03342759 chr3:160939853 NMD3 -0.84 -13.67 -0.59 2.94e-34 Morning vs. evening chronotype; LIHC cis rs2204008 0.683 rs7305703 chr12:38138381 T/C cg13010199 chr12:38710504 ALG10B 0.48 5.86 0.3 1.11e-8 Bladder cancer; LIHC cis rs561341 0.609 rs4795659 chr17:30187139 C/G cg13647721 chr17:30228624 UTP6 -0.69 -7.12 -0.36 6.45e-12 Hip circumference adjusted for BMI; LIHC cis rs10256972 0.521 rs10280960 chr7:1103697 A/G cg16145915 chr7:1198662 ZFAND2A -0.25 -5.87 -0.3 1.06e-8 Longevity;Endometriosis; LIHC cis rs6461049 0.800 rs3778977 chr7:2159746 C/T cg02951883 chr7:2050386 MAD1L1 -0.61 -9.96 -0.47 1.11e-20 Schizophrenia; LIHC cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg06481639 chr22:41940642 POLR3H -0.71 -7.09 -0.36 7.81e-12 Vitiligo; LIHC cis rs7772486 0.875 rs2748502 chr6:146298239 A/G cg23711669 chr6:146136114 FBXO30 0.59 10.12 0.48 3.12e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg02359409 chr6:42947317 PEX6 -0.44 -6.22 -0.32 1.45e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg19318889 chr4:1322082 MAEA 0.52 8.48 0.42 7.03e-16 Obesity-related traits; LIHC cis rs35110281 0.592 rs6417729 chr21:44967202 A/C cg01579765 chr21:45077557 HSF2BP -0.32 -5.88 -0.3 9.88e-9 Mean corpuscular volume; LIHC trans rs61931739 0.500 rs11053242 chr12:34511625 A/G cg26384229 chr12:38710491 ALG10B 0.63 8.12 0.4 8.29e-15 Morning vs. evening chronotype; LIHC cis rs7677751 0.943 rs9991165 chr4:55124591 A/G cg17187183 chr4:55093834 PDGFRA 0.69 8.07 0.4 1.22e-14 Corneal astigmatism; LIHC cis rs7100689 0.646 rs1290317 chr10:82062531 C/A cg01528321 chr10:82214614 TSPAN14 0.83 11.06 0.51 1.62e-24 Post bronchodilator FEV1; LIHC cis rs12995491 0.933 rs13008732 chr2:88528771 G/A cg04511125 chr2:88470314 THNSL2 -0.42 -6.39 -0.33 5.38e-10 Response to metformin (IC50); LIHC trans rs35110281 0.517 rs11089020 chr21:44939991 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.09 0.31 3.01e-9 Mean corpuscular volume; LIHC cis rs17376456 0.597 rs10064158 chr5:93095186 C/T cg25358565 chr5:93447407 FAM172A 0.81 7.78 0.39 8.84e-14 Diabetic retinopathy; LIHC cis rs2279817 1.000 rs35148872 chr1:18020184 G/A cg21791023 chr1:18019539 ARHGEF10L -0.64 -8.14 -0.4 7.29e-15 Neuroticism; LIHC cis rs782590 0.935 rs782568 chr2:55881538 T/C cg03859395 chr2:55845619 SMEK2 0.8 14.18 0.61 3.31e-36 Metabolic syndrome; LIHC cis rs826838 0.967 rs826855 chr12:39114888 T/C cg13010199 chr12:38710504 ALG10B -0.43 -6.06 -0.31 3.61e-9 Heart rate; LIHC cis rs10791323 0.572 rs10894755 chr11:133739685 C/T cg06766960 chr11:133703094 NA 0.45 6.8 0.35 4.57e-11 Childhood ear infection; LIHC cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg25072359 chr17:41440525 NA 0.36 5.76 0.3 1.89e-8 Menopause (age at onset); LIHC cis rs7903847 0.619 rs9888116 chr10:99159482 G/A cg08345082 chr10:99160200 RRP12 -0.39 -6.72 -0.34 7.76e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs17818399 0.712 rs13008088 chr2:46781580 C/G cg02822958 chr2:46747628 ATP6V1E2 0.5 7.66 0.38 1.91e-13 Height; LIHC cis rs12702595 0.509 rs11767985 chr7:7264352 A/C cg04827551 chr7:7268805 C1GALT1 0.33 6.16 0.32 2.06e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs6748734 1.000 rs4293565 chr2:241834770 A/G cg09990169 chr2:241835740 C2orf54 -0.66 -9.56 -0.46 2.43e-19 Urinary metabolites; LIHC cis rs9486715 0.867 rs1855533 chr6:97050265 T/C cg18709589 chr6:96969512 KIAA0776 -0.35 -6.3 -0.32 9.13e-10 Headache; LIHC cis rs208515 0.525 rs10498841 chr6:66663706 C/T cg07460842 chr6:66804631 NA 0.77 8.81 0.43 6.28e-17 Exhaled nitric oxide levels; LIHC cis rs6582630 0.555 rs10880625 chr12:38526612 A/C cg13010199 chr12:38710504 ALG10B 0.55 6.54 0.33 2.27e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs12887734 0.546 rs4900597 chr14:104266664 A/G cg24130564 chr14:104152367 KLC1 0.45 7.51 0.38 5.13e-13 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs1008375 0.966 rs6825133 chr4:17577776 C/T cg16339924 chr4:17578868 LAP3 0.45 6.22 0.32 1.44e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs754466 0.580 rs2289309 chr10:79571108 C/T cg17075019 chr10:79541650 NA -0.8 -12.68 -0.57 1.78e-30 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9649213 0.574 rs9648908 chr7:97945236 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs56104184 0.668 rs73063523 chr19:49408943 T/C cg21252483 chr19:49399788 TULP2 -0.98 -11.29 -0.52 2.41e-25 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs4908760 0.965 rs10864354 chr1:8549741 C/T cg20416874 chr1:8611966 RERE -0.66 -13.45 -0.59 2.22e-33 Vitiligo; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg08219700 chr8:58056026 NA 0.46 6.87 0.35 2.98e-11 Developmental language disorder (linguistic errors); LIHC cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg08499158 chr17:42289980 UBTF -0.49 -7.84 -0.39 5.96e-14 Total body bone mineral density; LIHC cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg22800045 chr5:56110881 MAP3K1 0.67 8.51 0.42 5.46e-16 Initial pursuit acceleration; LIHC cis rs3008870 1.000 rs3008859 chr1:67390999 G/C cg02640540 chr1:67518911 SLC35D1 0.42 5.78 0.3 1.64e-8 Lymphocyte percentage of white cells; LIHC cis rs3768617 0.510 rs12061219 chr1:183101471 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs1506636 0.927 rs6959270 chr7:123310628 G/A cg03229431 chr7:123269106 ASB15 -0.6 -12.22 -0.55 9.85e-29 Plateletcrit;Platelet count; LIHC cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg08822215 chr16:89438651 ANKRD11 -0.44 -6.79 -0.34 4.89e-11 Multiple myeloma (IgH translocation); LIHC cis rs2836974 0.644 rs4818017 chr21:40690561 G/T cg06238570 chr21:40685208 BRWD1 -0.55 -9.21 -0.45 3.46e-18 Cognitive function; LIHC cis rs1801251 0.896 rs2197563 chr2:233687080 G/A cg08000102 chr2:233561755 GIGYF2 -0.75 -11.22 -0.52 4.51e-25 Coronary artery disease; LIHC cis rs7614311 0.681 rs6801346 chr3:63947128 A/G cg22134162 chr3:63841271 THOC7 0.49 5.77 0.3 1.77e-8 Lung function (FVC);Lung function (FEV1); LIHC cis rs172166 0.694 rs1770131 chr6:28086413 C/T cg16479474 chr6:28041457 NA 0.39 6.52 0.33 2.57e-10 Cardiac Troponin-T levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11814422 chr18:47018265 SNORD58A;RPL17;SNORD58B 0.46 6.62 0.34 1.36e-10 Pancreatic cancer; LIHC cis rs870825 0.616 rs7659201 chr4:185632013 G/A cg04058563 chr4:185651563 MLF1IP 0.7 7.36 0.37 1.36e-12 Blood protein levels; LIHC cis rs4555082 0.834 rs11849607 chr14:105745383 G/A cg13114125 chr14:105738426 BRF1 -0.75 -9.76 -0.47 5.12e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs1559088 0.501 rs8100568 chr19:33567565 T/C cg27124370 chr19:33622961 WDR88 0.46 6.27 0.32 1.11e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs9902453 0.904 rs9900974 chr17:28364456 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.85 -0.6 6.1e-35 Coffee consumption (cups per day); LIHC cis rs782590 0.902 rs782602 chr2:55849309 A/G cg18811423 chr2:55921094 PNPT1 0.97 15.17 0.63 3.99e-40 Metabolic syndrome; LIHC cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg03806693 chr22:41940476 POLR3H -1.13 -13.39 -0.59 3.64e-33 Vitiligo; LIHC cis rs4684776 0.935 rs12636305 chr3:11418924 T/G cg00170343 chr3:11313890 ATG7 -0.43 -5.89 -0.3 9.39e-9 Small vessel stroke; LIHC cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg17747265 chr1:1875780 NA -0.59 -11.32 -0.52 1.84e-25 Body mass index; LIHC trans rs12019136 1 rs12019136 chr19:5835677 G/A cg16574191 chr19:14063234 PODNL1;DCAF15 -0.79 -6.22 -0.32 1.44e-9 Advanced age-related macular degeneration;IgG N-glycosylation phenotypes (multivariate analysis); LIHC cis rs9611565 0.649 rs2413659 chr22:42164862 A/G cg03806693 chr22:41940476 POLR3H 0.78 8.69 0.43 1.55e-16 Vitiligo; LIHC cis rs3790645 1.000 rs444482 chr1:26890648 C/G cg23229016 chr1:26872525 RPS6KA1 0.23 5.77 0.3 1.78e-8 Glucose homeostasis traits; LIHC cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg05564831 chr3:52568323 NT5DC2 0.4 6.63 0.34 1.28e-10 Bipolar disorder; LIHC cis rs9611565 0.592 rs9611612 chr22:41961189 T/C cg03806693 chr22:41940476 POLR3H -0.79 -8.97 -0.44 1.94e-17 Vitiligo; LIHC cis rs507080 0.922 rs518028 chr11:118564982 T/C cg04173919 chr11:118528438 PHLDB1 0.36 6.6 0.34 1.53e-10 Serum metabolite levels; LIHC cis rs2290416 0.579 rs58573550 chr8:144681714 G/A cg26536354 chr8:144654954 C8orf73 0.55 6.19 0.32 1.76e-9 Attention deficit hyperactivity disorder; LIHC cis rs6695567 1.000 rs6695567 chr1:53629585 G/A cg20326410 chr1:53600821 SLC1A7 0.3 6.35 0.32 6.87e-10 Systemic lupus erythematosus; LIHC cis rs17253792 0.822 rs76205307 chr14:56166038 C/T cg01858014 chr14:56050164 KTN1 -0.71 -7.3 -0.37 1.98e-12 Putamen volume; LIHC cis rs3749237 0.595 rs12489092 chr3:49550914 G/C cg02487422 chr3:49467188 NICN1 0.37 5.71 0.3 2.45e-8 Resting heart rate; LIHC cis rs2933343 0.700 rs6787833 chr3:128656184 A/G cg25356066 chr3:128598488 ACAD9 0.53 7.35 0.37 1.46e-12 IgG glycosylation; LIHC cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg02969873 chr4:1330999 MAEA -0.41 -6.31 -0.32 8.59e-10 Longevity; LIHC cis rs1577917 1.000 rs10944163 chr6:86658693 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.71 -0.34 7.87e-11 Response to antipsychotic treatment; LIHC cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 11.55 0.53 2.76e-26 Platelet count; LIHC cis rs2033908 0.589 rs4757060 chr11:12842990 G/A cg25843174 chr11:12811716 TEAD1 -0.26 -6.2 -0.32 1.63e-9 Sitting height ratio; LIHC cis rs11252926 0.966 rs11252923 chr10:566195 G/A cg16346588 chr10:242978 ZMYND11 -0.48 -5.89 -0.3 9.23e-9 Psychosis in Alzheimer's disease; LIHC cis rs921968 0.643 rs586374 chr2:219383003 A/C cg17980119 chr2:219472607 PLCD4 0.35 6.05 0.31 3.84e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9902453 0.817 rs12941382 chr17:28410124 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.92 -0.6 3.33e-35 Coffee consumption (cups per day); LIHC cis rs7100689 0.784 rs10749562 chr10:82108253 G/T cg01528321 chr10:82214614 TSPAN14 0.87 12.05 0.55 3.97e-28 Post bronchodilator FEV1; LIHC cis rs7715806 0.500 rs4704233 chr5:75000792 G/A cg19683494 chr5:74908142 NA 0.6 7.0 0.35 1.38e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7572733 0.515 rs893808 chr2:198860837 C/G cg10820045 chr2:198174542 NA 0.46 6.99 0.35 1.42e-11 Dermatomyositis; LIHC cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg17971929 chr21:40555470 PSMG1 -0.4 -6.19 -0.32 1.75e-9 Menarche (age at onset); LIHC cis rs10911251 0.546 rs3768625 chr1:183078712 G/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.78 0.5 1.63e-23 Colorectal cancer; LIHC cis rs11122272 0.735 rs973253 chr1:231520874 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs12701220 0.894 rs12539012 chr7:1052133 G/A cg04498913 chr7:1135747 C7orf50 0.37 5.71 0.3 2.4e-8 Bronchopulmonary dysplasia; LIHC cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg12310025 chr6:25882481 NA -0.61 -8.56 -0.42 3.9e-16 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15042806 chr16:23652268 DCTN5;PALB2 0.46 6.11 0.31 2.7e-9 Pancreatic cancer; LIHC cis rs9858542 0.953 rs6809216 chr3:49412559 G/A cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7914558 1.000 rs7067970 chr10:104913870 C/T cg15744005 chr10:104629667 AS3MT -0.39 -8.7 -0.43 1.43e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25275331 chr1:40723935 ZMPSTE24 -0.41 -6.1 -0.31 2.94e-9 Pancreatic cancer; LIHC cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg06618935 chr21:46677482 NA -0.3 -5.84 -0.3 1.19e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9837602 0.507 rs793448 chr3:99532949 G/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.91 0.35 2.42e-11 Breast cancer; LIHC cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 6.74 0.34 6.9e-11 Bipolar disorder; LIHC cis rs12702595 0.818 rs7791957 chr7:7270034 T/C cg04827551 chr7:7268805 C1GALT1 0.37 6.7 0.34 8.49e-11 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21815882 chr7:26241064 CBX3;HNRNPA2B1 0.4 6.34 0.32 7.43e-10 Cognitive function; LIHC cis rs6461049 0.765 rs1476887 chr7:2151633 T/C cg14004847 chr7:1930337 MAD1L1 -0.42 -6.12 -0.31 2.55e-9 Schizophrenia; LIHC cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg27297192 chr10:134578999 INPP5A 0.53 7.43 0.37 8.83e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1728785 0.818 rs1728769 chr16:68564186 C/T cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs11696739 0.536 rs3761268 chr20:1601167 C/T cg15722679 chr20:1638393 SIRPG 0.55 9.88 0.47 2.12e-20 Mean platelet volume; LIHC cis rs57244997 0.544 rs77182940 chr6:162443721 T/C cg17173639 chr6:162384350 PARK2 -0.6 -7.46 -0.37 7e-13 Mosquito bite size; LIHC cis rs7131987 0.650 rs11050187 chr12:29472876 T/C cg05697976 chr12:29376483 FAR2 0.31 6.17 0.32 1.9e-9 QT interval; LIHC cis rs5769765 0.862 rs138857 chr22:50199589 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.67 -8.01 -0.4 1.76e-14 Schizophrenia; LIHC cis rs11630290 0.592 rs1039818 chr15:64155296 A/G cg12036633 chr15:63758958 NA 0.63 6.75 0.34 6.36e-11 Iris characteristics; LIHC cis rs4604732 0.631 rs12031694 chr1:247623653 C/T cg02104434 chr1:247694406 LOC148824;OR2C3 0.25 5.86 0.3 1.07e-8 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs4555082 0.834 rs2735817 chr14:105717796 A/G cg06808227 chr14:105710500 BRF1 0.5 6.27 0.32 1.06e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs6912958 0.525 rs242262 chr6:88018057 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.63 0.53 1.38e-26 Monocyte percentage of white cells; LIHC trans rs526821 0.574 rs11230156 chr11:55334809 A/G cg15704280 chr7:45808275 SEPT13 -0.51 -7.79 -0.39 7.89e-14 Pediatric bone mineral density (spine); LIHC cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.48 0.46 4.54e-19 Electroencephalogram traits; LIHC cis rs4727027 0.933 rs2158633 chr7:148832652 C/T cg23583168 chr7:148888333 NA -0.74 -10.49 -0.49 1.65e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs4853012 0.838 rs58759652 chr2:74344902 A/T cg01017244 chr2:74357527 NA 0.63 11.25 0.52 3.44e-25 Gestational age at birth (maternal effect); LIHC cis rs6442522 0.610 rs6808644 chr3:15527047 G/A cg16303742 chr3:15540471 COLQ 0.4 6.39 0.33 5.45e-10 Uric acid levels; LIHC cis rs10751667 0.666 rs7394992 chr11:980690 G/C cg10932868 chr11:921992 NA 0.4 7.56 0.38 3.84e-13 Alzheimer's disease (late onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04104609 chr2:219523980 ZNF142;BCS1L 0.38 6.1 0.31 2.91e-9 Lung function (FEV1/FVC); LIHC cis rs77861329 1.000 rs114209632 chr3:52188361 C/T cg08692210 chr3:52188851 WDR51A 0.81 7.23 0.36 3.12e-12 Macrophage inflammatory protein 1b levels; LIHC cis rs4906332 0.933 rs34606394 chr14:103915636 G/A cg19000871 chr14:103996768 TRMT61A -0.46 -7.82 -0.39 6.67e-14 Coronary artery disease; LIHC cis rs17685 0.712 rs1859794 chr7:75821544 G/A cg04592579 chr7:75616294 TMEM120A 0.4 6.9 0.35 2.6e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg23758822 chr17:41437982 NA 0.96 18.2 0.7 2.94e-52 Menopause (age at onset); LIHC cis rs9649213 0.593 rs6945554 chr7:97972946 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs13113518 0.812 rs56055342 chr4:56407095 T/C cg15358633 chr12:38710606 ALG10B 0.43 6.11 0.31 2.65e-9 Height; LIHC cis rs796364 0.760 rs1569178 chr2:201024512 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -8.23 -0.41 3.99e-15 Schizophrenia; LIHC cis rs12188164 0.543 rs2672757 chr5:454732 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.47 7.01 0.35 1.25e-11 Cystic fibrosis severity; LIHC cis rs1538970 0.961 rs884962 chr1:45847981 G/A cg05343316 chr1:45956843 TESK2 0.59 8.92 0.43 2.8e-17 Platelet count; LIHC cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg23982607 chr1:1823379 GNB1 -0.67 -13.29 -0.58 8.44e-33 Body mass index; LIHC cis rs9733 0.621 rs12746899 chr1:150579678 A/T cg17724175 chr1:150552817 MCL1 -0.37 -7.53 -0.38 4.46e-13 Tonsillectomy; LIHC cis rs7618501 0.633 rs2526748 chr3:50080439 A/G cg24110177 chr3:50126178 RBM5 0.49 8.02 0.4 1.73e-14 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.669 rs11040455 chr11:49669829 G/C cg03929089 chr4:120376271 NA -0.52 -8.84 -0.43 5.33e-17 Height; LIHC cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg07424592 chr7:64974309 NA -0.8 -9.32 -0.45 1.44e-18 Diabetic kidney disease; LIHC cis rs7927771 0.864 rs755553 chr11:47432303 G/A cg20135002 chr11:47629003 NA 0.56 9.53 0.46 3.03e-19 Subjective well-being; LIHC cis rs7107174 1.000 rs729354 chr11:77962453 T/A cg02023728 chr11:77925099 USP35 0.48 9.14 0.44 5.68e-18 Testicular germ cell tumor; LIHC cis rs8062405 0.755 rs62034358 chr16:28587597 G/T cg16576597 chr16:28551801 NUPR1 0.49 7.59 0.38 3.13e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs5769765 0.908 rs9616376 chr22:50310829 A/G cg02269571 chr22:50332266 NA -0.75 -9.95 -0.47 1.14e-20 Schizophrenia; LIHC cis rs8017423 0.967 rs11849641 chr14:90727647 T/C cg14092571 chr14:90743983 NA -0.38 -6.02 -0.31 4.54e-9 Mortality in heart failure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16993936 chr10:13146903 OPTN -0.44 -6.86 -0.35 3.34e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs3780486 0.846 rs3780487 chr9:33139237 T/C cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs4713118 0.616 rs9348789 chr6:28025486 C/T cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs67460515 0.567 rs34691229 chr3:160876897 G/T cg17135325 chr3:160939158 NMD3 0.6 8.69 0.43 1.48e-16 Parkinson's disease; LIHC cis rs722599 0.748 rs20578 chr14:75367807 C/T cg11812906 chr14:75593930 NEK9 -0.43 -6.99 -0.35 1.47e-11 IgG glycosylation; LIHC trans rs208515 0.525 rs10498841 chr6:66663706 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.78 0.43 8.06e-17 Exhaled nitric oxide levels; LIHC cis rs870825 0.616 rs6552807 chr4:185640531 A/G cg04058563 chr4:185651563 MLF1IP 0.77 7.79 0.39 8.15e-14 Blood protein levels; LIHC cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.61 0.34 1.44e-10 Bipolar disorder; LIHC cis rs12479064 0.724 rs62153852 chr2:99934713 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.64 -7.88 -0.39 4.48e-14 Chronic sinus infection; LIHC cis rs7552404 1.000 rs11163924 chr1:76132070 A/C cg03433033 chr1:76189801 ACADM -0.67 -9.5 -0.46 3.64e-19 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs79976124 0.837 rs10455591 chr6:66650584 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.77 0.34 5.54e-11 Type 2 diabetes; LIHC cis rs10838687 0.800 rs4752983 chr11:47352138 C/T cg26139080 chr11:47293733 MADD -0.42 -5.83 -0.3 1.27e-8 Proinsulin levels; LIHC cis rs7534824 0.625 rs6692186 chr1:101470217 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 6.76 0.34 5.97e-11 Refractive astigmatism; LIHC cis rs1008375 1.000 rs28693609 chr4:17645233 C/T cg15017067 chr4:17643749 FAM184B 0.34 5.87 0.3 1.02e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs72781680 0.898 rs72780123 chr2:23996009 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs34779708 0.966 rs57081218 chr10:35434608 A/G cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.4e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12188164 0.543 rs7728027 chr5:459943 T/C cg26076054 chr5:421317 AHRR 0.27 5.97 0.31 5.91e-9 Cystic fibrosis severity; LIHC cis rs8072100 0.905 rs8077106 chr17:45653291 T/G cg08085267 chr17:45401833 C17orf57 0.57 8.45 0.42 8.54e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg22800045 chr5:56110881 MAP3K1 0.67 8.51 0.42 5.54e-16 Initial pursuit acceleration; LIHC cis rs2243480 1.000 rs778691 chr7:65873092 G/C cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs9611565 0.504 rs5758452 chr22:42144927 G/A cg06634786 chr22:41940651 POLR3H 0.56 6.07 0.31 3.46e-9 Vitiligo; LIHC cis rs508618 0.638 rs479200 chr1:231543780 G/A cg06096015 chr1:231504339 EGLN1 0.43 7.26 0.37 2.64e-12 Red blood cell count; LIHC cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg00149659 chr3:10157352 C3orf10 0.68 7.2 0.36 3.97e-12 Alzheimer's disease; LIHC cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg10802521 chr3:52805072 NEK4 -0.43 -7.26 -0.37 2.55e-12 Bipolar disorder; LIHC cis rs9811920 0.609 rs793465 chr3:99627750 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs765787 0.530 rs2433228 chr15:45515371 A/C cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs965469 1.000 rs6051716 chr20:3267736 C/T cg25506879 chr20:3388711 C20orf194 -0.59 -6.67 -0.34 1e-10 IFN-related cytopenia; LIHC cis rs916888 0.773 rs199443 chr17:44819565 C/T cg15921436 chr17:44337874 NA 0.64 6.52 0.33 2.59e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7615952 0.599 rs67575510 chr3:125742355 C/G cg05084668 chr3:125655381 ALG1L -0.41 -6.39 -0.33 5.28e-10 Blood pressure (smoking interaction); LIHC cis rs12477438 0.520 rs6739579 chr2:99731552 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 13.93 0.6 3.03e-35 Chronic sinus infection; LIHC cis rs919433 0.680 rs1961558 chr2:198487278 C/T cg03934865 chr2:198174659 NA 0.51 7.68 0.38 1.66e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1348850 0.668 rs6734683 chr2:178494012 C/G cg27490568 chr2:178487706 NA 0.7 9.33 0.45 1.37e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2562152 0.786 rs216594 chr16:103009 A/T cg02949481 chr16:131562 MPG 0.48 7.11 0.36 6.64e-12 Glioblastoma; LIHC cis rs6952808 0.771 rs4719336 chr7:1916397 T/C cg04267008 chr7:1944627 MAD1L1 -0.57 -8.55 -0.42 4.13e-16 Bipolar disorder and schizophrenia; LIHC cis rs6088590 1.000 rs6058111 chr20:33310999 T/C cg08999081 chr20:33150536 PIGU 0.37 5.73 0.3 2.22e-8 Coronary artery disease; LIHC cis rs1046896 0.552 rs12602280 chr17:80805421 G/C cg19500275 chr17:80737654 TBCD 0.41 5.73 0.3 2.2e-8 Glycated hemoglobin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02837703 chr11:67236413 TMEM134 0.45 6.38 0.33 5.77e-10 Lung function (FEV1/FVC); LIHC cis rs7847628 0.587 rs4837796 chr9:123610288 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.74 -13.04 -0.58 8.03e-32 Birth weight; LIHC cis rs875971 0.755 rs10228885 chr7:65780529 C/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg04267008 chr7:1944627 MAD1L1 -0.55 -8.6 -0.42 2.83e-16 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.41 0.61 3.94e-37 Prudent dietary pattern; LIHC cis rs4901869 0.966 rs4901868 chr14:59333792 C/T cg02291164 chr14:59296302 NA -0.46 -5.83 -0.3 1.27e-8 Panic disorder; LIHC trans rs877282 0.838 rs34912955 chr10:772222 T/C cg22713356 chr15:30763199 NA 1.4 12.55 0.56 5.75e-30 Uric acid levels; LIHC cis rs3790645 1.000 rs1064196 chr1:26887592 C/T cg23229016 chr1:26872525 RPS6KA1 -0.24 -6.23 -0.32 1.36e-9 Glucose homeostasis traits; LIHC cis rs7715806 0.500 rs17563610 chr5:74981322 A/T cg00601450 chr5:74908170 NA 0.59 7.17 0.36 4.61e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8084351 0.577 rs4371227 chr18:50657284 C/T cg24270629 chr18:50823537 DCC -0.43 -6.36 -0.33 6.41e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs10733682 0.524 rs10987418 chr9:129462563 A/G cg00232160 chr9:129468157 NA 0.39 6.95 0.35 1.84e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg20607798 chr8:58055168 NA 0.49 6.11 0.31 2.75e-9 Developmental language disorder (linguistic errors); LIHC cis rs6964587 0.692 rs17672805 chr7:91573466 A/G cg17063962 chr7:91808500 NA -0.64 -11.26 -0.52 3.18e-25 Breast cancer; LIHC cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg16970926 chr12:29381810 FAR2 0.3 6.24 0.32 1.3e-9 QT interval; LIHC cis rs7911264 0.628 rs7921040 chr10:94418425 G/A cg25506282 chr10:94462361 NA 0.38 6.46 0.33 3.56e-10 Inflammatory bowel disease; LIHC cis rs807669 0.807 rs698422 chr22:19205826 A/T cg02655711 chr22:19163373 SLC25A1 0.38 7.11 0.36 6.95e-12 Metabolite levels; LIHC cis rs875971 1.000 rs811880 chr7:65818646 T/C cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs6951245 0.554 rs35126802 chr7:1134842 C/T cg04025307 chr7:1156635 C7orf50 0.64 6.34 0.32 7.25e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs240764 0.687 rs239209 chr6:101140977 T/C cg12253828 chr6:101329408 ASCC3 0.43 6.48 0.33 3.14e-10 Neuroticism; LIHC cis rs5769765 0.954 rs1569954 chr22:50244071 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.67 8.91 0.43 3e-17 Schizophrenia; LIHC cis rs7666738 0.606 rs10006454 chr4:99080361 G/A cg05340658 chr4:99064831 C4orf37 0.65 11.69 0.53 8.52e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04902049 chr1:36622448 MAP7D1 0.42 6.18 0.32 1.81e-9 Pancreatic cancer; LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs9911578 0.967 rs2429369 chr17:56501420 A/G cg05425664 chr17:57184151 TRIM37 -0.57 -8.59 -0.42 3.25e-16 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg11766577 chr21:47581405 C21orf56 -0.39 -6.22 -0.32 1.44e-9 Testicular germ cell tumor; LIHC cis rs16866061 1.000 rs72974219 chr2:225423784 G/C cg12698349 chr2:225449008 CUL3 0.8 13.96 0.6 2.22e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs2842992 0.915 rs2842958 chr6:160108425 A/G cg11366901 chr6:160182831 ACAT2 0.93 15.25 0.64 2.01e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs16828019 0.777 rs35496942 chr1:41488904 G/A cg03962019 chr1:41807865 NA 0.5 7.0 0.35 1.38e-11 Intelligence (multi-trait analysis); LIHC cis rs921968 0.565 rs755112 chr2:219606052 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.9e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2439831 0.702 rs2467402 chr15:44024490 A/C cg02155558 chr15:43621948 ADAL;LCMT2 -0.54 -6.81 -0.35 4.45e-11 Lung cancer in ever smokers; LIHC cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg02931644 chr1:25747376 RHCE 0.33 7.08 0.36 8.47e-12 Erythrocyte sedimentation rate; LIHC cis rs365132 1.000 rs2292256 chr5:176333126 C/T cg16309518 chr5:176445507 NA -0.58 -11.52 -0.53 3.76e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg05665937 chr4:1216051 CTBP1 0.45 6.05 0.31 3.86e-9 Obesity-related traits; LIHC cis rs6748734 0.843 rs6749674 chr2:241834501 G/C cg09990169 chr2:241835740 C2orf54 -0.66 -9.51 -0.46 3.52e-19 Urinary metabolites; LIHC cis rs3106136 0.527 rs2865345 chr4:95156565 A/G cg11021082 chr4:95130006 SMARCAD1 -0.48 -8.98 -0.44 1.81e-17 Capecitabine sensitivity; LIHC cis rs2522056 1.000 rs2522063 chr5:131805591 G/T cg24060327 chr5:131705240 SLC22A5 0.55 7.44 0.37 8.01e-13 Lymphocyte counts;Fibrinogen; LIHC cis rs12477438 0.520 rs6542863 chr2:99725138 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.05 0.6 1.02e-35 Chronic sinus infection; LIHC trans rs11098499 0.754 rs12510269 chr4:120241646 A/G cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs2120019 0.938 rs2289582 chr15:75310394 T/C cg09165964 chr15:75287851 SCAMP5 -0.61 -9.54 -0.46 2.87e-19 Blood trace element (Zn levels); LIHC cis rs9783347 1.000 rs4150610 chr11:18364140 A/G cg15585147 chr11:18324498 HPS5 0.43 6.77 0.34 5.74e-11 Pancreatic cancer; LIHC cis rs2576037 0.583 rs10070 chr18:44388899 G/A cg19077165 chr18:44547161 KATNAL2 -0.47 -7.08 -0.36 8.26e-12 Personality dimensions; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg14817848 chr12:12715558 DUSP16 -0.51 -7.7 -0.38 1.46e-13 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7903847 0.544 rs61861865 chr10:99144867 C/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7131987 0.903 rs2216853 chr12:29413248 C/G cg05697976 chr12:29376483 FAR2 0.33 6.76 0.34 6.05e-11 QT interval; LIHC cis rs9549367 0.789 rs6577035 chr13:113879997 G/A cg00898013 chr13:113819073 PROZ -0.43 -7.45 -0.37 7.91e-13 Platelet distribution width; LIHC cis rs909002 0.962 rs10798883 chr1:32140305 C/T cg13919466 chr1:32135498 COL16A1 -0.36 -7.14 -0.36 5.69e-12 Intelligence (multi-trait analysis); LIHC cis rs2408955 0.500 rs12816820 chr12:48558325 A/G cg21466736 chr12:48725269 NA -0.63 -9.13 -0.44 6.16e-18 Glycated hemoglobin levels; LIHC cis rs9303401 0.573 rs35104446 chr17:57180234 A/C cg25039879 chr17:56429692 SUPT4H1 0.76 8.87 0.43 4.17e-17 Cognitive test performance; LIHC cis rs6582630 0.531 rs3850000 chr12:38483752 T/C cg13010199 chr12:38710504 ALG10B 0.46 6.14 0.31 2.35e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg08822215 chr16:89438651 ANKRD11 -0.4 -6.29 -0.32 9.94e-10 Multiple myeloma (IgH translocation); LIHC cis rs6066825 0.590 rs6063307 chr20:47304045 A/G cg18078177 chr20:47281410 PREX1 0.47 8.11 0.4 9.16e-15 Colorectal cancer; LIHC cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs72772090 1.000 rs56116814 chr5:96048714 G/A cg17330273 chr5:96107758 CAST;ERAP1 -0.48 -5.86 -0.3 1.07e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2953145 0.568 rs2975752 chr2:241521327 A/G cg07929629 chr2:241523174 NA 0.58 8.45 0.42 8.28e-16 Bipolar disorder; LIHC cis rs743757 1.000 rs2073496 chr3:50431142 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.5 7.92 0.39 3.42e-14 Diastolic blood pressure; LIHC cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg00343986 chr7:65444356 GUSB 0.44 6.24 0.32 1.31e-9 Calcium levels; LIHC cis rs7772486 0.875 rs1331639 chr6:146431869 A/G cg23711669 chr6:146136114 FBXO30 -0.59 -10.14 -0.48 2.67e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 1.000 rs2815361 chr1:67494591 G/T cg02640540 chr1:67518911 SLC35D1 0.44 6.08 0.31 3.29e-9 Lymphocyte percentage of white cells; LIHC cis rs2012796 0.957 rs8009083 chr14:81818289 A/G cg02996355 chr14:81879375 NA 0.41 6.31 0.32 8.87e-10 Night sleep phenotypes; LIHC cis rs10870270 0.956 rs7915388 chr10:133734972 G/A cg08754478 chr10:133766260 PPP2R2D -0.56 -8.27 -0.41 3.08e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs8180040 0.620 rs6768722 chr3:47079112 G/A cg27129171 chr3:47204927 SETD2 0.54 9.08 0.44 8.92e-18 Colorectal cancer; LIHC trans rs2797160 0.935 rs6940748 chr6:125994080 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.44 -6.26 -0.32 1.16e-9 Endometrial cancer; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg06873352 chr17:61820015 STRADA -0.73 -12.98 -0.57 1.32e-31 Prudent dietary pattern; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg01766191 chr11:57103423 SSRP1 -0.45 -6.05 -0.31 3.83e-9 Alopecia areata; LIHC cis rs34779708 0.931 rs2490663 chr10:35329735 A/G cg03585969 chr10:35415529 CREM -0.75 -11.42 -0.53 8.56e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9868809 0.881 rs13096357 chr3:48675856 C/A cg07636037 chr3:49044803 WDR6 -0.55 -6.19 -0.32 1.77e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs4474465 0.688 rs7108439 chr11:78277708 A/T cg27205649 chr11:78285834 NARS2 0.5 7.82 0.39 6.55e-14 Alzheimer's disease (survival time); LIHC cis rs7833986 0.501 rs2719259 chr8:56941630 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.73 7.65 0.38 2.03e-13 Height; LIHC cis rs644799 1.000 rs12786522 chr11:95522858 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.32 0.68 1.09e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2576037 0.583 rs2164104 chr18:44567743 G/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.42 5.87 0.3 1.04e-8 Personality dimensions; LIHC cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg12373951 chr3:133503437 NA 0.55 9.43 0.45 6.44e-19 Iron status biomarkers; LIHC cis rs6121246 0.909 rs6089071 chr20:30378384 C/G cg13852791 chr20:30311386 BCL2L1 0.91 9.25 0.45 2.53e-18 Mean corpuscular hemoglobin; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg22903471 chr2:27725779 GCKR -0.46 -7.92 -0.39 3.38e-14 Total body bone mineral density; LIHC cis rs6582630 0.502 rs11520261 chr12:38332019 T/G cg26384229 chr12:38710491 ALG10B 0.59 8.15 0.4 7.03e-15 Drug-induced liver injury (flucloxacillin); LIHC trans rs3749237 0.964 rs2352975 chr3:49891885 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.61 9.41 0.45 7.76e-19 Resting heart rate; LIHC cis rs6942756 1.000 rs2718084 chr7:128897342 T/C cg02491457 chr7:128862824 NA 0.73 11.92 0.54 1.27e-27 White matter hyperintensity burden; LIHC cis rs7762018 0.655 rs2184195 chr6:170148397 C/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.77 0.34 5.71e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs1814175 0.619 rs847644 chr11:49918418 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg06240896 chr7:100136768 AGFG2 0.42 6.05 0.31 3.76e-9 Migraine with aura; LIHC trans rs916888 0.821 rs199525 chr17:44847834 T/G cg16836995 chr17:43662488 NA -0.73 -7.2 -0.36 3.74e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7512552 0.773 rs3737240 chr1:150483355 C/T cg15654264 chr1:150340011 RPRD2 0.71 11.37 0.52 1.27e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs1801251 0.964 rs7589201 chr2:233724536 A/G cg25237894 chr2:233734115 C2orf82 -0.58 -11.46 -0.53 5.97e-26 Coronary artery disease; LIHC cis rs12464483 0.524 rs4952172 chr2:30888286 A/G cg17749961 chr2:30669863 LCLAT1 -0.48 -6.23 -0.32 1.4e-9 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs6582630 0.502 rs11181230 chr12:38300085 A/G cg26384229 chr12:38710491 ALG10B 0.6 8.19 0.4 5.23e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs875971 0.964 rs2161065 chr7:65932905 A/G cg18876405 chr7:65276391 NA 0.38 6.86 0.35 3.22e-11 Aortic root size; LIHC cis rs17854409 1.000 rs16983290 chr20:61478894 A/G cg07645718 chr20:61493192 TCFL5 -0.7 -6.16 -0.32 2.07e-9 Obesity-related traits; LIHC cis rs854765 0.647 rs854769 chr17:18019011 A/G cg04398451 chr17:18023971 MYO15A 0.72 12.12 0.55 2.26e-28 Total body bone mineral density; LIHC cis rs738722 1.000 rs1807609 chr22:29131129 T/C cg15103426 chr22:29168792 CCDC117 0.43 5.87 0.3 1.03e-8 Optic cup area;Esophageal cancer and gastric cancer; LIHC cis rs2839186 0.872 rs13046834 chr21:47701485 T/C cg05896524 chr21:47604654 C21orf56 0.44 6.64 0.34 1.25e-10 Testicular germ cell tumor; LIHC cis rs1559088 0.947 rs10403238 chr19:33552405 A/G cg27124370 chr19:33622961 WDR88 0.47 7.06 0.36 9.22e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs10876993 0.672 rs2640611 chr12:58037757 T/A cg15848620 chr12:58087721 OS9 -0.55 -7.43 -0.37 8.57e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs11718455 0.960 rs4682713 chr3:44013191 G/C cg08738300 chr3:44038990 NA 0.52 9.0 0.44 1.55e-17 Coronary artery disease; LIHC cis rs8017423 0.934 rs2401874 chr14:90682467 C/T cg04374321 chr14:90722782 PSMC1 0.73 14.04 0.6 1.15e-35 Mortality in heart failure; LIHC cis rs9611565 0.607 rs132792 chr22:42062822 C/T cg03806693 chr22:41940476 POLR3H 0.81 9.14 0.44 5.55e-18 Vitiligo; LIHC cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.9 7.74 0.39 1.11e-13 Platelet count; LIHC cis rs2997447 0.706 rs61776622 chr1:26469035 A/G cg19633962 chr1:26362018 EXTL1 -0.7 -6.33 -0.32 7.75e-10 QRS complex (12-leadsum); LIHC trans rs11098499 0.691 rs28396837 chr4:120271541 G/A cg25214090 chr10:38739885 LOC399744 0.44 7.28 0.37 2.26e-12 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04051962 chr16:1570409 IFT140 0.38 6.08 0.31 3.19e-9 Longevity; LIHC cis rs250677 0.522 rs3763022 chr5:148381078 A/G cg12140854 chr5:148520817 ABLIM3 -0.44 -5.95 -0.31 6.73e-9 Breast cancer; LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2742540 0.503 rs11042121 chr11:8932640 A/C cg00186954 chr11:8933980 ST5;C11orf17 0.38 6.39 0.33 5.57e-10 Hematocrit; LIHC trans rs7022054 0.502 rs5010022 chr9:7216586 G/A cg26740341 chr6:22874184 NA 0.27 6.24 0.32 1.28e-9 Schizophrenia; LIHC cis rs2115536 0.730 rs4238512 chr15:80183898 A/C cg00225070 chr15:80189496 MTHFS -0.6 -9.8 -0.47 3.7e-20 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.956 rs10896343 chr11:68317860 G/C cg16797656 chr11:68205561 LRP5 0.51 8.09 0.4 1.06e-14 Total body bone mineral density; LIHC cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg18305652 chr10:134549665 INPP5A -0.43 -6.4 -0.33 5.11e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7918232 0.574 rs10458708 chr10:27455605 C/T cg14240646 chr10:27532245 ACBD5 -0.68 -11.08 -0.51 1.44e-24 Breast cancer; LIHC cis rs2336384 1.000 rs6672267 chr1:12054911 A/G cg13216073 chr1:12042593 MFN2 0.43 6.38 0.33 5.61e-10 Platelet count; LIHC cis rs739401 0.527 rs418832 chr11:3072236 C/T cg20651018 chr11:3035856 CARS -0.35 -5.83 -0.3 1.29e-8 Longevity; LIHC cis rs72772090 0.710 rs1559085 chr5:96078702 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.64 -7.26 -0.37 2.71e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC trans rs9951602 0.512 rs8089108 chr18:76651361 C/T cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC cis rs2180341 0.814 rs9321085 chr6:127735361 T/C cg27446573 chr6:127587934 RNF146 0.79 13.09 0.58 5.05e-32 Breast cancer; LIHC cis rs8044995 0.563 rs73613962 chr16:68361974 T/G cg09835421 chr16:68378352 PRMT7 -0.82 -9.43 -0.45 6.2800000000000005e-19 Schizophrenia; LIHC cis rs11583043 0.874 rs11578366 chr1:101396852 T/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.52 0.46 3.1400000000000002e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2016586 0.802 rs8142446 chr22:36115128 A/G cg26342177 chr22:36113512 APOL5 -0.38 -6.49 -0.33 3.01e-10 Body mass index; LIHC cis rs1419980 0.673 rs1978284 chr12:7771151 G/A cg14906510 chr12:7781169 NA 0.47 7.32 0.37 1.82e-12 HDL cholesterol levels; LIHC cis rs908922 0.676 rs4112786 chr1:152532872 T/A cg20991723 chr1:152506922 NA 0.55 9.08 0.44 8.68e-18 Hair morphology; LIHC cis rs6545883 0.965 rs1992765 chr2:61751333 A/G cg15711740 chr2:61764176 XPO1 -0.44 -6.22 -0.32 1.43e-9 Tuberculosis; LIHC cis rs6545883 0.894 rs10177303 chr2:61594459 G/A cg14146966 chr2:61757674 XPO1 -0.43 -7.24 -0.36 2.94e-12 Tuberculosis; LIHC cis rs11677370 0.603 rs10174064 chr2:3849806 C/T cg17052675 chr2:3827356 NA -0.52 -6.68 -0.34 9.91e-11 Type 2 diabetes; LIHC cis rs11758351 0.866 rs77889957 chr6:26207435 A/G cg06951627 chr6:26196580 NA 0.53 6.27 0.32 1.07e-9 Gout;Renal underexcretion gout; LIHC cis rs1707322 0.963 rs4660900 chr1:46419605 T/C cg06784218 chr1:46089804 CCDC17 0.36 6.44 0.33 3.94e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11190604 1.000 rs10883512 chr10:102308516 A/G cg07080220 chr10:102295463 HIF1AN 0.51 7.1 0.36 7.39e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17428076 0.801 rs62182392 chr2:172721762 G/A cg13550731 chr2:172543902 DYNC1I2 0.36 5.89 0.3 9.09e-9 Myopia; LIHC cis rs66573146 0.831 rs66645969 chr4:6985614 G/A cg00086871 chr4:6988644 TBC1D14 0.8 5.98 0.31 5.57e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs208520 0.609 rs208436 chr6:66897470 G/A cg07460842 chr6:66804631 NA -0.47 -5.8 -0.3 1.54e-8 Exhaled nitric oxide output; LIHC cis rs2257205 0.667 rs8070007 chr17:56709169 A/G cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs963731 0.649 rs297129 chr2:39299271 C/T cg04010122 chr2:39346883 SOS1 0.64 5.8 0.3 1.54e-8 Corticobasal degeneration; LIHC cis rs2153535 0.601 rs4140584 chr6:8540614 C/G cg07606381 chr6:8435919 SLC35B3 -0.78 -11.27 -0.52 2.8e-25 Motion sickness; LIHC trans rs61931739 0.500 rs11519398 chr12:34473553 C/T cg26384229 chr12:38710491 ALG10B 0.75 8.85 0.43 4.68e-17 Morning vs. evening chronotype; LIHC cis rs10870270 1.000 rs7077744 chr10:133770201 C/T cg08754478 chr10:133766260 PPP2R2D -0.54 -8.03 -0.4 1.58e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1499280 0.920 rs10471365 chr5:52108572 T/C cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs875971 1.000 rs778696 chr7:65870813 C/G cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs13108904 0.557 rs1250098 chr4:1238256 A/T cg16405210 chr4:1374714 KIAA1530 0.7 10.44 0.49 2.57e-22 Obesity-related traits; LIHC cis rs6545883 0.965 rs12713439 chr2:61752154 G/A cg14146966 chr2:61757674 XPO1 0.47 8.24 0.41 3.77e-15 Tuberculosis; LIHC cis rs10089 0.903 rs6862701 chr5:127391249 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.16e-11 Ileal carcinoids; LIHC cis rs265548 0.646 rs36692 chr19:17906839 C/T cg21960279 chr19:17905606 B3GNT3 0.55 8.63 0.42 2.36e-16 Tumor biomarkers; LIHC cis rs8180040 0.587 rs62246398 chr3:47066203 A/C cg16586182 chr3:47516702 SCAP 0.47 8.57 0.42 3.7e-16 Colorectal cancer; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.66 0.56 2.18e-30 Prudent dietary pattern; LIHC cis rs9916302 0.851 rs11657899 chr17:37626963 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg14159672 chr1:205819179 PM20D1 0.61 8.42 0.41 1.04e-15 Menarche (age at onset); LIHC cis rs2404602 0.692 rs35077207 chr15:76935306 A/G cg03037974 chr15:76606532 NA 0.75 14.56 0.62 1.04e-37 Blood metabolite levels; LIHC cis rs6421571 0.565 rs10892263 chr11:118587319 T/C cg19308663 chr11:118741387 NA 0.42 5.73 0.3 2.24e-8 Primary biliary cholangitis; LIHC cis rs11871801 0.918 rs4633765 chr17:40682341 T/A cg14558262 chr17:40713999 COASY -0.5 -6.83 -0.35 3.91e-11 Crohn's disease; LIHC cis rs801193 0.569 rs2659908 chr7:66160822 G/A cg18252515 chr7:66147081 NA -0.47 -6.86 -0.35 3.26e-11 Aortic root size; LIHC cis rs6831352 0.918 rs1126672 chr4:100047812 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7618501 1.000 rs7634902 chr3:49762662 G/T cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs425535 0.619 rs12498174 chr4:74825768 T/C cg02530824 chr4:74847766 PF4 -0.37 -5.95 -0.31 6.57e-9 Blood protein levels; LIHC cis rs2274273 0.868 rs1572611 chr14:55833874 T/A cg01864836 chr14:55583639 NA -0.38 -6.65 -0.34 1.19e-10 Protein biomarker; LIHC cis rs7772486 0.875 rs7767660 chr6:146436550 T/C cg23711669 chr6:146136114 FBXO30 0.58 10.05 0.48 5.41e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs2115630 1.000 rs58581703 chr15:85276935 C/T cg12501888 chr15:85177176 SCAND2 -0.5 -7.84 -0.39 5.74e-14 P wave terminal force; LIHC cis rs10463316 0.894 rs6875014 chr5:150754345 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -6.16 -0.32 2.04e-9 Metabolite levels (Pyroglutamine); LIHC cis rs875971 1.000 rs2420820 chr7:66091907 T/C cg12463550 chr7:65579703 CRCP -0.42 -5.93 -0.31 7.51e-9 Aortic root size; LIHC cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg05025164 chr4:1340916 KIAA1530 0.62 10.39 0.49 3.83e-22 Obesity-related traits; LIHC cis rs2204008 0.748 rs11180579 chr12:38237830 A/G cg13010199 chr12:38710504 ALG10B 0.5 5.85 0.3 1.16e-8 Bladder cancer; LIHC cis rs600806 0.778 rs891379 chr1:110003605 A/G cg11161837 chr1:110010384 SYPL2 0.47 6.15 0.32 2.17e-9 Intelligence (multi-trait analysis); LIHC trans rs6598955 0.671 rs11247909 chr1:26640135 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.76 -7.8 -0.39 7.42e-14 Obesity-related traits; LIHC cis rs11969893 0.850 rs9498414 chr6:101322976 C/T cg12253828 chr6:101329408 ASCC3 0.81 10.19 0.48 1.88e-21 Economic and political preferences (immigration/crime); LIHC cis rs600806 0.854 rs10745353 chr1:109877506 A/G cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.45 -0.37 7.79e-13 Intelligence (multi-trait analysis); LIHC cis rs72627509 0.587 rs17087401 chr4:57901155 G/T cg26694713 chr4:57773883 REST 0.59 7.46 0.37 7.3e-13 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs735539 0.645 rs1052209 chr13:21216850 C/T cg27234864 chr13:21295941 IL17D 0.42 6.09 0.31 3.07e-9 Dental caries; LIHC cis rs4629710 0.592 rs13200165 chr6:131549167 G/C cg12606694 chr6:131520996 AKAP7 0.64 7.38 0.37 1.25e-12 Multiple myeloma (IgH translocation); LIHC cis rs9921222 0.521 rs9935268 chr16:381562 G/C cg12437481 chr16:420112 MRPL28 -0.61 -8.52 -0.42 5.04e-16 Bone mineral density (spine);Bone mineral density; LIHC cis rs79149102 0.579 rs58294763 chr15:75299768 G/A cg09165964 chr15:75287851 SCAMP5 -0.59 -7.76 -0.39 1.01e-13 Lung cancer; LIHC cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.64e-30 Menopause (age at onset); LIHC cis rs250677 0.687 rs171636 chr5:148434545 G/A cg12140854 chr5:148520817 ABLIM3 -0.52 -5.81 -0.3 1.4e-8 Breast cancer; LIHC cis rs16854884 0.609 rs2885197 chr3:143636616 A/T cg06585982 chr3:143692056 C3orf58 -0.54 -7.26 -0.37 2.56e-12 Economic and political preferences (feminism/equality); LIHC cis rs7131987 0.903 rs2216853 chr12:29413248 C/G cg14222432 chr12:29376421 FAR2 0.36 7.05 0.36 9.82e-12 QT interval; LIHC cis rs7927592 0.913 rs3740631 chr11:68341722 T/G cg01657329 chr11:68192670 LRP5 -0.48 -6.22 -0.32 1.46e-9 Total body bone mineral density; LIHC trans rs10847980 0.623 rs28681105 chr12:123875525 T/C cg07919128 chr17:18022025 MYO15A -0.75 -7.5 -0.38 5.62e-13 Adiponectin levels; LIHC trans rs1005277 0.540 rs11011351 chr10:38030525 A/G cg23533926 chr12:111358616 MYL2 -0.32 -6.23 -0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12477438 0.735 rs12474477 chr2:99690408 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.87 -0.51 7.74e-24 Chronic sinus infection; LIHC cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27613455 chr17:38020644 IKZF3 0.39 6.64 0.34 1.22e-10 Cognitive function; LIHC cis rs7619427 0.544 rs9877020 chr3:43992455 A/G cg24966902 chr3:44043705 NA -0.43 -6.62 -0.34 1.43e-10 Schizophrenia; LIHC cis rs7587476 0.765 rs2121284 chr2:215656260 T/C cg04004882 chr2:215674386 BARD1 -0.55 -7.77 -0.39 9.06e-14 Neuroblastoma; LIHC cis rs3741404 0.560 rs2875748 chr11:63915537 G/A cg18225595 chr11:63971243 STIP1 -0.59 -9.32 -0.45 1.42e-18 Platelet count; LIHC cis rs2439831 0.867 rs2470134 chr15:43849886 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.69 -9.67 -0.46 1.04e-19 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07157506 chr18:12883603 PTPN2 0.45 6.94 0.35 1.96e-11 Pancreatic cancer; LIHC cis rs56104184 0.775 rs73061699 chr19:49400511 T/C cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs12497850 0.897 rs7432989 chr3:49105136 A/G cg07636037 chr3:49044803 WDR6 0.94 17.07 0.68 1.12e-47 Parkinson's disease; LIHC cis rs4713118 0.955 rs9468206 chr6:27690453 G/T cg20933634 chr6:27740509 NA 0.48 6.35 0.32 6.8e-10 Parkinson's disease; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg21983178 chr1:45120676 TMEM53 0.41 6.18 0.32 1.84e-9 Immature fraction of reticulocytes; LIHC cis rs1371867 0.846 rs1660312 chr8:101330634 C/G cg06636551 chr8:101224915 SPAG1 -0.48 -8.84 -0.43 5.25e-17 Atrioventricular conduction; LIHC cis rs7107174 1.000 rs2511156 chr11:77971167 G/C cg02023728 chr11:77925099 USP35 0.49 9.25 0.45 2.46e-18 Testicular germ cell tumor; LIHC trans rs2744203 1.000 rs72610886 chr6:104647207 C/G cg27088726 chr16:83171155 CDH13 -0.46 -6.08 -0.31 3.14e-9 IgG glycosylation; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02676523 chr16:4027674 ADCY9 -0.43 -6.5 -0.33 2.78e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg11644478 chr21:40555479 PSMG1 0.83 10.48 0.49 1.76e-22 Cognitive function; LIHC cis rs7572733 0.534 rs700673 chr2:198692929 A/G cg03934865 chr2:198174659 NA 0.45 6.53 0.33 2.35e-10 Dermatomyositis; LIHC cis rs2832191 0.791 rs2832179 chr21:30480366 C/T cg08807101 chr21:30365312 RNF160 -0.63 -10.01 -0.48 7.61e-21 Dental caries; LIHC cis rs4555082 0.830 rs2255575 chr14:105727251 T/C cg13114125 chr14:105738426 BRF1 -0.69 -9.18 -0.44 4.15e-18 Mean platelet volume;Platelet distribution width; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg20623868 chr19:15666885 NA -0.39 -6.05 -0.31 3.77e-9 Triglycerides; LIHC cis rs2235642 0.582 rs2235637 chr16:1567694 G/A cg09065629 chr16:1709722 CRAMP1L 0.35 6.03 0.31 4.34e-9 Coronary artery disease; LIHC cis rs3741404 0.609 rs641430 chr11:63869531 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.69 -11.21 -0.52 4.56e-25 Platelet count; LIHC cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg13395646 chr4:1353034 KIAA1530 -0.39 -5.85 -0.3 1.16e-8 Longevity; LIHC cis rs734999 0.566 rs4648658 chr1:2560882 G/A cg18854424 chr1:2615690 NA -0.34 -7.53 -0.38 4.64e-13 Ulcerative colitis; LIHC trans rs9914544 0.545 rs2305064 chr17:18770733 G/A cg21372672 chr17:16614065 CCDC144A -0.28 -6.73 -0.34 7.38e-11 Educational attainment (years of education); LIHC cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.15 0.36 5.45e-12 Bipolar disorder; LIHC cis rs11971779 0.616 rs10269683 chr7:139100868 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg21724239 chr8:58056113 NA 0.5 6.51 0.33 2.61e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg08280861 chr8:58055591 NA 0.55 6.26 0.32 1.13e-9 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg21016266 chr12:122356598 WDR66 0.43 6.95 0.35 1.9e-11 Mean corpuscular volume; LIHC cis rs10949834 0.517 rs810536 chr7:73504233 G/A cg07137043 chr7:73588983 EIF4H 0.52 6.42 0.33 4.67e-10 Verbal memory performance (residualized delayed recall change); LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg09177884 chr7:1199841 ZFAND2A -0.49 -7.28 -0.37 2.37e-12 Longevity;Endometriosis; LIHC cis rs7771547 0.573 rs7744363 chr6:36424665 A/C cg07856975 chr6:36356162 ETV7 -0.35 -5.77 -0.3 1.8e-8 Platelet distribution width; LIHC cis rs7208859 0.673 rs73265612 chr17:29225983 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9611565 0.592 rs5758405 chr22:42076381 C/A cg03806693 chr22:41940476 POLR3H 0.82 9.35 0.45 1.15e-18 Vitiligo; LIHC cis rs1113500 0.805 rs11185244 chr1:108601147 C/T cg06207961 chr1:108661230 NA 0.31 5.71 0.3 2.44e-8 Growth-regulated protein alpha levels; LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg20102877 chr2:27665638 KRTCAP3 -0.41 -5.74 -0.3 2.08e-8 Total body bone mineral density; LIHC cis rs10256972 0.933 rs35696159 chr7:1047194 A/G cg07308232 chr7:1071921 C7orf50 -0.5 -8.22 -0.41 4.26e-15 Longevity;Endometriosis; LIHC trans rs11088226 0.681 rs1015047 chr21:33949423 A/G cg09050820 chr6:167586206 TCP10L2 0.87 14.85 0.63 7.65e-39 Gastritis; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs1046896 0.627 rs7225515 chr17:80795783 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.39 0.33 5.4e-10 Glycated hemoglobin levels; LIHC cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg16497277 chr3:49208875 KLHDC8B -0.51 -6.49 -0.33 2.96e-10 Menarche (age at onset); LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg27432699 chr2:27873401 GPN1 -0.53 -7.64 -0.38 2.26e-13 Total body bone mineral density; LIHC cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg03264133 chr6:25882463 NA -0.42 -6.52 -0.33 2.5e-10 Height; LIHC trans rs11098499 0.954 rs4345162 chr4:120312959 G/A cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg02951883 chr7:2050386 MAD1L1 -0.78 -13.78 -0.6 1.17e-34 Bipolar disorder and schizophrenia; LIHC trans rs9929218 0.551 rs2296406 chr16:68721340 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.94 23.48 0.79 2.8e-73 Colorectal cancer; LIHC cis rs35110281 0.712 rs167930 chr21:44946625 G/A cg01579765 chr21:45077557 HSF2BP -0.31 -5.78 -0.3 1.72e-8 Mean corpuscular volume; LIHC cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg27094323 chr7:1216898 NA -0.4 -5.88 -0.3 9.8e-9 Longevity;Endometriosis; LIHC trans rs4906332 0.966 rs59858038 chr14:103867102 C/T cg17675199 chr6:35436792 RPL10A 0.32 6.36 0.33 6.34e-10 Coronary artery disease; LIHC cis rs9916302 0.731 rs11868030 chr17:37650332 A/G cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs4474465 0.850 rs10793332 chr11:78270020 C/G cg27205649 chr11:78285834 NARS2 0.39 5.93 0.31 7.41e-9 Alzheimer's disease (survival time); LIHC cis rs763121 0.853 rs2413546 chr22:39107001 G/A cg14440974 chr22:39074834 NA -0.44 -7.14 -0.36 5.81e-12 Menopause (age at onset); LIHC cis rs2073499 1.000 rs3806708 chr3:50306249 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.69 7.9 0.39 3.79e-14 Schizophrenia; LIHC cis rs9443189 0.950 rs1280039 chr6:76514940 C/T cg01950844 chr6:76311363 SENP6 0.48 5.74 0.3 2.1e-8 Prostate cancer; LIHC cis rs7107174 0.681 rs11237443 chr11:78005089 C/A cg02023728 chr11:77925099 USP35 0.5 9.7 0.46 7.91e-20 Testicular germ cell tumor; LIHC cis rs1577917 0.958 rs34622605 chr6:86456519 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.1 -0.51 1.13e-24 Response to antipsychotic treatment; LIHC trans rs12478296 1.000 rs55742408 chr2:243041077 G/A cg01596870 chr19:55963115 NA -0.64 -8.65 -0.42 2.07e-16 Obesity-related traits; LIHC cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg04546413 chr19:29218101 NA 0.56 10.35 0.49 4.97e-22 Methadone dose in opioid dependence; LIHC cis rs3736594 0.513 rs62138971 chr2:27840754 G/A cg27432699 chr2:27873401 GPN1 0.48 7.16 0.36 5.12e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6665290 0.901 rs61834005 chr1:227202789 C/T cg10327440 chr1:227177885 CDC42BPA -1.15 -27.54 -0.83 8.62e-89 Myeloid white cell count; LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.53 7.8 0.39 7.61e-14 Lymphocyte counts; LIHC cis rs3741404 0.825 rs11604782 chr11:63946650 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.99 16.75 0.67 2.06e-46 Platelet count; LIHC cis rs6547741 1.000 rs6547741 chr2:27855924 G/A cg27432699 chr2:27873401 GPN1 0.78 12.9 0.57 2.66e-31 Oral cavity cancer; LIHC cis rs7818688 0.654 rs896848 chr8:95981810 G/A cg16049864 chr8:95962084 TP53INP1 0.56 6.31 0.32 8.77e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs7618501 1.000 rs2234391 chr3:49842625 A/G cg21659725 chr3:3221576 CRBN 0.96 18.62 0.71 6.55e-54 Intelligence (multi-trait analysis); LIHC trans rs637571 0.615 rs10160792 chr11:65667149 C/G cg17712092 chr4:129076599 LARP1B 0.84 14.49 0.62 1.92e-37 Eosinophil percentage of white cells; LIHC trans rs2243480 1.000 rs58669269 chr7:65951953 T/C cg10756647 chr7:56101905 PSPH 1.0 11.41 0.53 8.84e-26 Diabetic kidney disease; LIHC cis rs644799 0.509 rs561635 chr11:95634232 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.51 -7.81 -0.39 6.95e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg00750074 chr16:89608354 SPG7 -0.5 -8.1 -0.4 9.85e-15 Multiple myeloma (IgH translocation); LIHC cis rs3736485 0.966 rs8040538 chr15:51904584 G/A cg08986416 chr15:51914746 DMXL2 -0.44 -6.3 -0.32 9.07e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1419980 0.730 rs11054871 chr12:7770878 C/G cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs9790314 0.791 rs6809256 chr3:161026513 G/A cg03342759 chr3:160939853 NMD3 -0.8 -13.24 -0.58 1.31e-32 Morning vs. evening chronotype; LIHC cis rs600806 0.854 rs11142 chr1:109897103 A/G cg16275483 chr1:110013120 SYPL2 -0.49 -6.13 -0.31 2.4e-9 Intelligence (multi-trait analysis); LIHC cis rs9297145 0.724 rs62473013 chr7:98762418 G/T cg05967295 chr7:98741636 SMURF1 0.73 10.38 0.49 4.11e-22 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg08280861 chr8:58055591 NA 0.52 6.2 0.32 1.64e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs9902453 1.000 rs7223786 chr17:28332107 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.73 -0.54 6.15e-27 Coffee consumption (cups per day); LIHC cis rs2197308 0.740 rs10880619 chr12:37922720 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs1403694 0.695 rs13095338 chr3:186435583 T/C cg12454167 chr3:186435060 KNG1 0.38 8.75 0.43 9.76e-17 Blood protein levels; LIHC cis rs12497850 0.931 rs9311434 chr3:48884147 T/C cg06212747 chr3:49208901 KLHDC8B 0.57 7.39 0.37 1.11e-12 Parkinson's disease; LIHC cis rs11190604 1.000 rs3750629 chr10:102275727 A/G cg07080220 chr10:102295463 HIF1AN 0.58 8.71 0.43 1.35e-16 Palmitoleic acid (16:1n-7) levels; LIHC cis rs4319547 0.695 rs4758648 chr12:122900460 A/G cg23029597 chr12:123009494 RSRC2 -0.5 -7.19 -0.36 4.14e-12 Body mass index; LIHC cis rs4969178 0.600 rs2376583 chr17:76402105 A/T cg20026190 chr17:76395443 PGS1 0.39 5.82 0.3 1.39e-8 HDL cholesterol levels; LIHC cis rs1005277 0.557 rs1854563 chr10:38434961 G/A cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2346177 0.874 rs11125075 chr2:46656344 A/G cg02822958 chr2:46747628 ATP6V1E2 0.4 6.07 0.31 3.4e-9 HDL cholesterol; LIHC cis rs8081395 0.801 rs2665405 chr17:57875292 G/A cg13753209 chr17:57696993 CLTC -0.45 -6.96 -0.35 1.78e-11 White blood cell count; LIHC cis rs10791323 0.572 rs4412766 chr11:133742811 A/C cg06766960 chr11:133703094 NA -0.44 -6.78 -0.34 5.18e-11 Childhood ear infection; LIHC cis rs546131 0.642 rs7946980 chr11:34820438 C/T cg06937548 chr11:34938143 PDHX;APIP 0.48 6.43 0.33 4.38e-10 Lung disease severity in cystic fibrosis; LIHC cis rs2073499 0.935 rs28365992 chr3:50340996 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.62 6.92 0.35 2.26e-11 Schizophrenia; LIHC cis rs10791097 0.629 rs11222361 chr11:130731424 T/G cg14779329 chr11:130786720 SNX19 0.38 5.88 0.3 9.95e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9916302 0.904 rs8077104 chr17:37530510 A/G cg03013999 chr17:37608204 MED1 -0.36 -5.95 -0.31 6.7e-9 Glomerular filtration rate (creatinine); LIHC cis rs8060686 0.641 rs7188085 chr16:68113873 A/G cg05110241 chr16:68378359 PRMT7 -0.53 -6.08 -0.31 3.16e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs875971 0.862 rs7796162 chr7:65745758 T/C cg18252515 chr7:66147081 NA 0.46 6.81 0.35 4.35e-11 Aortic root size; LIHC cis rs703842 0.642 rs73123375 chr12:58063664 C/T cg15848620 chr12:58087721 OS9 0.51 6.41 0.33 4.86e-10 Multiple sclerosis; LIHC cis rs722599 0.748 rs61978948 chr14:75363369 G/A cg08847533 chr14:75593920 NEK9 -0.57 -9.16 -0.44 4.75e-18 IgG glycosylation; LIHC cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC cis rs8010715 0.785 rs2877611 chr14:24595430 C/T cg23112188 chr14:24563095 PCK2 -0.28 -5.77 -0.3 1.76e-8 IgG glycosylation; LIHC cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg06634786 chr22:41940651 POLR3H -0.75 -7.71 -0.38 1.35e-13 Vitiligo; LIHC cis rs1005277 0.505 rs10827836 chr10:38215441 A/G cg00409905 chr10:38381863 ZNF37A 0.55 9.33 0.45 1.34e-18 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.72 0.39 1.3e-13 Prudent dietary pattern; LIHC cis rs7666738 0.515 rs13142498 chr4:98792443 G/T cg05340658 chr4:99064831 C4orf37 0.49 6.36 0.33 6.5e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20818191 chr4:866154 GAK 0.48 6.97 0.35 1.59e-11 Longevity; LIHC cis rs3892630 0.878 rs8108621 chr19:33183291 G/A cg22980127 chr19:33182716 NUDT19 1.05 12.48 0.56 9.97e-30 Red blood cell traits; LIHC cis rs7762018 1.000 rs6923339 chr6:170128033 T/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.53 6.1 0.31 2.79e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6952808 0.756 rs12537348 chr7:1948172 C/G cg02951883 chr7:2050386 MAD1L1 -0.62 -9.28 -0.45 1.93e-18 Bipolar disorder and schizophrenia; LIHC cis rs4319547 0.695 rs10734915 chr12:122873408 A/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.26 -0.37 2.68e-12 Body mass index; LIHC cis rs2075371 0.932 rs34664116 chr7:133984878 G/A cg20476274 chr7:133979776 SLC35B4 0.7 9.4 0.45 8.17e-19 Mean platelet volume; LIHC cis rs644799 1.000 rs473155 chr11:95596873 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.64 8.71 0.43 1.33e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.83 0.63 9.29e-39 Prudent dietary pattern; LIHC cis rs317689 0.581 rs160829 chr12:69769538 G/C cg20891283 chr12:69753455 YEATS4 0.83 16.39 0.66 5.97e-45 Response to diuretic therapy; LIHC cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg13047869 chr3:10149882 C3orf24 0.54 6.49 0.33 2.99e-10 Alzheimer's disease; LIHC cis rs7617773 0.539 rs13094496 chr3:48387050 G/C cg11946769 chr3:48343235 NME6 0.6 7.4 0.37 1.09e-12 Coronary artery disease; LIHC cis rs2153535 0.580 rs9378552 chr6:8463748 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.65 0.42 1.97e-16 Motion sickness; LIHC trans rs11098499 0.954 rs10031483 chr4:120422636 T/C cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs2153535 0.580 rs4365970 chr6:8453813 C/T cg21535247 chr6:8435926 SLC35B3 -0.61 -8.06 -0.4 1.33e-14 Motion sickness; LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg14004847 chr7:1930337 MAD1L1 -0.49 -7.34 -0.37 1.59e-12 Schizophrenia; LIHC cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg18357526 chr6:26021779 HIST1H4A 0.43 6.45 0.33 3.82e-10 Height; LIHC cis rs11098499 0.754 rs34425882 chr4:120253177 G/A cg09307838 chr4:120376055 NA 0.7 10.98 0.51 3.2e-24 Corneal astigmatism; LIHC cis rs2153535 0.580 rs9393023 chr6:8469994 T/G cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs2637266 0.783 rs12268496 chr10:78487192 G/A cg18941641 chr10:78392320 NA 0.27 5.75 0.3 2.02e-8 Pulmonary function; LIHC cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg18305652 chr10:134549665 INPP5A 0.44 6.37 0.33 5.95e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg02951883 chr7:2050386 MAD1L1 -0.6 -9.49 -0.46 3.95e-19 Bipolar disorder and schizophrenia; LIHC cis rs6089829 1.000 rs62207535 chr20:61669187 A/G cg08564027 chr20:61660810 NA 0.37 6.71 0.34 7.95e-11 Prostate cancer (SNP x SNP interaction); LIHC cis rs34375054 0.672 rs2291248 chr12:125619308 C/T cg25124228 chr12:125621409 AACS -0.42 -7.0 -0.35 1.39e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs6088590 1.000 rs6088615 chr20:33400474 C/T cg06115741 chr20:33292138 TP53INP2 -0.55 -7.75 -0.39 1.04e-13 Coronary artery disease; LIHC cis rs3749237 0.555 rs2117939 chr3:49415179 C/A cg07636037 chr3:49044803 WDR6 0.49 7.46 0.37 7.04e-13 Resting heart rate; LIHC cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg05590025 chr7:65112418 INTS4L2 0.64 7.14 0.36 5.49e-12 Diabetic kidney disease; LIHC trans rs3780486 1.000 rs3780480 chr9:33163486 G/T cg20290983 chr6:43655470 MRPS18A 1.04 19.37 0.72 6.21e-57 IgG glycosylation; LIHC cis rs35110281 0.686 rs162399 chr21:44950020 G/A cg01579765 chr21:45077557 HSF2BP -0.34 -6.12 -0.31 2.6e-9 Mean corpuscular volume; LIHC cis rs1865760 0.566 rs9467663 chr6:26021456 C/G cg18357526 chr6:26021779 HIST1H4A 0.49 7.23 0.36 3.24e-12 Height; LIHC cis rs9811920 0.609 rs812657 chr3:99566329 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.13 0.36 6.18e-12 Axial length; LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.95 0.57 1.78e-31 Prudent dietary pattern; LIHC cis rs769267 0.965 rs2023882 chr19:19405405 T/C cg03709012 chr19:19516395 GATAD2A 0.94 15.76 0.65 1.93e-42 Tonsillectomy; LIHC cis rs9372498 0.536 rs1761624 chr6:118642722 C/T cg01339444 chr6:118972232 C6orf204 0.76 6.35 0.32 6.89e-10 Diastolic blood pressure; LIHC cis rs35110281 0.693 rs4819290 chr21:45122713 C/T cg21573476 chr21:45109991 RRP1B -0.52 -10.17 -0.48 2.08e-21 Mean corpuscular volume; LIHC cis rs10849689 1 rs10849689 chr12:110493222 A/G cg12870014 chr12:110450643 ANKRD13A 0.8 10.45 0.49 2.34e-22 Schizophrenia; LIHC cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg09417038 chr21:47716443 C21orf57 -0.47 -7.1 -0.36 7.2e-12 Testicular germ cell tumor; LIHC cis rs425277 1.000 rs12401379 chr1:2058580 G/C cg24578937 chr1:2090814 PRKCZ 0.45 7.49 0.38 5.94e-13 Height; LIHC cis rs950169 0.922 rs62029585 chr15:84951874 C/G cg03959625 chr15:84868606 LOC388152 0.46 6.51 0.33 2.67e-10 Schizophrenia; LIHC cis rs1538970 1.000 rs4520450 chr1:45834773 A/G cg24296786 chr1:45957014 TESK2 -0.5 -7.46 -0.37 7.12e-13 Platelet count; LIHC cis rs34172651 0.517 rs1465423 chr16:24772680 C/G cg00152838 chr16:24741724 TNRC6A 0.5 6.28 0.32 1.03e-9 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg18404041 chr3:52824283 ITIH1 -0.55 -8.9 -0.43 3.26e-17 Bipolar disorder; LIHC cis rs9326248 0.911 rs11216284 chr11:117003060 C/T cg11861562 chr11:117069780 TAGLN 0.49 8.15 0.4 6.89e-15 Blood protein levels; LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg02951883 chr7:2050386 MAD1L1 -0.75 -12.56 -0.56 4.98e-30 Bipolar disorder and schizophrenia; LIHC cis rs2242116 0.796 rs4587 chr3:46963502 T/C cg02527881 chr3:46936655 PTH1R -0.46 -9.4 -0.45 8.13e-19 Birth weight; LIHC trans rs10411161 0.702 rs8110073 chr19:52383123 C/A cg22319618 chr22:45562946 NUP50 -0.59 -8.05 -0.4 1.41e-14 Breast cancer; LIHC cis rs60871478 0.947 rs62432862 chr7:807719 G/C cg13844804 chr7:814759 HEATR2 0.43 5.73 0.3 2.25e-8 Cerebrospinal P-tau181p levels; LIHC cis rs1577917 0.771 rs2842612 chr6:86303091 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.88 -0.39 4.39e-14 Response to antipsychotic treatment; LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg14893161 chr1:205819251 PM20D1 -0.61 -8.75 -0.43 9.63e-17 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04213235 chr1:145826932 GPR89A 0.47 6.74 0.34 6.65e-11 Pancreatic cancer; LIHC cis rs2153535 0.601 rs9502719 chr6:8541032 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.51 0.42 5.35e-16 Motion sickness; LIHC cis rs11098499 0.865 rs4001305 chr4:120359236 G/T cg09307838 chr4:120376055 NA 0.78 12.45 0.56 1.29e-29 Corneal astigmatism; LIHC cis rs3741151 1.000 rs75109191 chr11:73023532 T/C cg17517138 chr11:73019481 ARHGEF17 0.96 7.04 0.36 1.06e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs1577917 0.958 rs12202712 chr6:86578541 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -7.95 -0.4 2.66e-14 Response to antipsychotic treatment; LIHC cis rs2108225 0.934 rs2190392 chr7:107452685 T/C cg18560240 chr7:107437656 SLC26A3 -0.39 -5.81 -0.3 1.45e-8 Ulcerative colitis; LIHC cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg03806693 chr22:41940476 POLR3H -1.12 -12.95 -0.57 1.75e-31 Vitiligo; LIHC cis rs910316 0.726 rs175040 chr14:75469555 A/G cg08847533 chr14:75593920 NEK9 -0.86 -17.57 -0.69 1.09e-49 Height; LIHC cis rs11792861 0.589 rs2176692 chr9:111927723 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.51 6.49 0.33 3.07e-10 Menarche (age at onset); LIHC cis rs67311347 0.866 rs11712426 chr3:40330322 G/A cg18306943 chr3:40428807 ENTPD3 0.36 6.02 0.31 4.48e-9 Renal cell carcinoma; LIHC cis rs7833986 0.501 rs2667999 chr8:56950474 T/C cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.77 0.43 8.58e-17 Height; LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg11494091 chr17:61959527 GH2 0.43 7.97 0.4 2.46e-14 Prudent dietary pattern; LIHC cis rs74181299 0.571 rs2302647 chr2:65283174 G/A cg05010058 chr2:65284262 CEP68 0.37 5.96 0.31 6.35e-9 Pulse pressure; LIHC cis rs3106136 0.678 rs7685514 chr4:95292089 T/C cg11021082 chr4:95130006 SMARCAD1 0.35 6.1 0.31 2.9e-9 Capecitabine sensitivity; LIHC cis rs7412746 0.658 rs12410394 chr1:150860186 G/A cg18016565 chr1:150552671 MCL1 0.52 9.88 0.47 2.09e-20 Melanoma; LIHC cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs4919694 1.000 rs17787717 chr10:104695699 T/G cg04362960 chr10:104952993 NT5C2 1.09 7.82 0.39 6.53e-14 Arsenic metabolism; LIHC cis rs11871801 0.517 rs665268 chr17:40722029 A/G cg14558262 chr17:40713999 COASY 0.63 9.76 0.47 5.2e-20 Crohn's disease; LIHC cis rs921968 0.541 rs58650092 chr2:219304851 C/A cg02985541 chr2:219472218 PLCD4 -0.43 -6.95 -0.35 1.86e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9818758 0.607 rs35673421 chr3:49139406 G/A cg00383909 chr3:49044727 WDR6 0.84 7.15 0.36 5.14e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1707322 0.827 rs12125508 chr1:46246010 A/G cg06784218 chr1:46089804 CCDC17 0.39 6.98 0.35 1.53e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9399135 0.967 rs6929661 chr6:135328792 G/A cg24558204 chr6:135376177 HBS1L 0.42 6.92 0.35 2.24e-11 Red blood cell count; LIHC cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg11764359 chr7:65958608 NA 0.61 6.44 0.33 4.09e-10 Diabetic kidney disease; LIHC cis rs36051895 0.632 rs10974982 chr9:5149382 G/C cg02405213 chr9:5042618 JAK2 -0.68 -12.22 -0.55 9.28e-29 Pediatric autoimmune diseases; LIHC cis rs9583531 0.891 rs7999536 chr13:111382199 G/A cg24331049 chr13:111365604 ING1 0.67 8.97 0.44 2.01e-17 Coronary artery disease; LIHC cis rs910316 1.000 rs10149880 chr14:75633008 A/G cg08847533 chr14:75593920 NEK9 -0.87 -18.87 -0.71 6.06e-55 Height; LIHC cis rs9392556 0.626 rs626080 chr6:4101567 A/G cg10424681 chr6:4079350 C6orf201;C6orf146 -0.24 -6.1 -0.31 2.86e-9 Blood metabolite levels; LIHC cis rs3617 0.625 rs11719137 chr3:52876389 G/T cg11645453 chr3:52864694 ITIH4 -0.23 -6.19 -0.32 1.71e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9682041 0.561 rs7643214 chr3:170144281 C/T cg11886554 chr3:170076028 SKIL 0.78 5.94 0.31 6.94e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs4948275 0.550 rs7082786 chr10:63176990 C/A cg03237606 chr10:63212265 TMEM26 0.34 7.67 0.38 1.8e-13 Night sleep phenotypes; LIHC cis rs9640161 0.789 rs10952250 chr7:150025966 T/C cg10018233 chr7:150070692 REPIN1 0.56 9.45 0.46 5.53e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs3814244 0.528 rs12582272 chr12:68400078 T/A cg15249341 chr12:68405565 NA -0.31 -6.09 -0.31 3e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs8192917 0.832 rs9671454 chr14:25102056 G/C cg08766149 chr14:25103301 GZMB 0.33 7.24 0.36 2.92e-12 Vitiligo; LIHC cis rs4843747 0.671 rs72818577 chr16:88111181 G/A cg00677901 chr16:88017247 BANP 0.53 8.25 0.41 3.35e-15 Menopause (age at onset); LIHC cis rs2795502 1.000 rs2795502 chr10:43340662 G/A cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs6088580 0.634 rs1205334 chr20:32930369 T/C cg08999081 chr20:33150536 PIGU -0.68 -13.18 -0.58 2.31e-32 Glomerular filtration rate (creatinine); LIHC cis rs6430585 0.878 rs9677760 chr2:136538939 T/A cg07169764 chr2:136633963 MCM6 -0.98 -13.62 -0.59 4.82e-34 Corneal structure; LIHC cis rs8062405 0.723 rs4788077 chr16:28569764 G/C cg00204512 chr16:28754710 NA 0.41 7.13 0.36 6e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs910316 0.737 rs398896 chr14:75482827 C/A cg11812906 chr14:75593930 NEK9 -0.73 -13.64 -0.59 4.06e-34 Height; LIHC cis rs10791323 0.569 rs329664 chr11:133754975 G/T cg06766960 chr11:133703094 NA -0.4 -6.1 -0.31 2.8e-9 Childhood ear infection; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg13508402 chr7:127670570 SND1;LRRC4 0.38 6.06 0.31 3.65e-9 Bilirubin levels; LIHC cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 9.13 0.44 6.1e-18 Bipolar disorder; LIHC cis rs611744 0.967 rs677288 chr8:109177539 T/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs11608355 0.515 rs56244055 chr12:109936211 G/A cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs2280018 0.609 rs2941253 chr16:15173746 G/A cg07549590 chr16:15018862 NA -0.33 -6.2 -0.32 1.66e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9326248 0.953 rs634960 chr11:117072963 T/C cg26566898 chr11:117069891 TAGLN -0.48 -7.49 -0.38 5.84e-13 Blood protein levels; LIHC cis rs11690935 0.731 rs10930491 chr2:172569824 A/G cg13550731 chr2:172543902 DYNC1I2 0.62 11.62 0.53 1.6e-26 Schizophrenia; LIHC cis rs7818688 0.697 rs28399553 chr8:95906794 A/G cg16049864 chr8:95962084 TP53INP1 0.58 6.64 0.34 1.25e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1448094 0.605 rs12367761 chr12:86286894 T/C cg02569458 chr12:86230093 RASSF9 0.46 6.09 0.31 3.1e-9 Major depressive disorder; LIHC cis rs6951245 0.872 rs57068908 chr7:1060084 A/C cg08132940 chr7:1081526 C7orf50 -0.7 -6.11 -0.31 2.68e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6545883 0.794 rs778152 chr2:61608540 C/A cg14146966 chr2:61757674 XPO1 -0.44 -7.42 -0.37 9.46e-13 Tuberculosis; LIHC cis rs668210 0.947 rs610497 chr11:65765551 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.52 6.79 0.34 5.1e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs7208859 0.623 rs11650982 chr17:29129955 A/G cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10791097 0.739 rs12279359 chr11:130730544 G/A cg12179176 chr11:130786555 SNX19 0.73 11.5 0.53 4.27e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs17376456 0.569 rs17083377 chr5:93164870 C/G cg25358565 chr5:93447407 FAM172A 0.76 7.42 0.37 9.11e-13 Diabetic retinopathy; LIHC cis rs6788895 1.000 rs79709238 chr3:150488477 A/C cg07663535 chr3:150480033 SIAH2 0.56 7.02 0.35 1.23e-11 Breast cancer; LIHC cis rs2032447 0.531 rs428469 chr6:25898624 G/A cg07061783 chr6:25882402 NA -0.83 -9.92 -0.47 1.48e-20 Intelligence (multi-trait analysis); LIHC cis rs5753037 0.702 rs9614055 chr22:30187702 C/T cg01021169 chr22:30184971 ASCC2 -0.36 -6.95 -0.35 1.86e-11 Type 1 diabetes; LIHC cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg05564831 chr3:52568323 NT5DC2 0.36 5.82 0.3 1.33e-8 Electroencephalogram traits; LIHC cis rs2070488 0.662 rs7373930 chr3:38454931 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.56 7.81 0.39 7.16e-14 Electrocardiographic conduction measures; LIHC cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg03709012 chr19:19516395 GATAD2A -0.92 -15.73 -0.65 2.52e-42 Tonsillectomy; LIHC cis rs17685 0.753 rs13240967 chr7:75658197 C/T cg01364799 chr7:75623366 TMEM120A 0.51 7.75 0.39 1.05e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2153535 0.601 rs2143353 chr6:8530111 T/G cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs965469 0.895 rs6139123 chr20:3396634 C/T cg25506879 chr20:3388711 C20orf194 -0.53 -6.21 -0.32 1.51e-9 IFN-related cytopenia; LIHC cis rs6089829 0.851 rs6122346 chr20:61661822 C/G cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg17372223 chr3:52568218 NT5DC2 0.36 6.01 0.31 4.75e-9 Electroencephalogram traits; LIHC cis rs10870270 0.957 rs3753008 chr10:133785129 A/C cg08754478 chr10:133766260 PPP2R2D -0.55 -8.36 -0.41 1.6e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1816752 0.905 rs4769348 chr13:24975113 G/A cg22771759 chr13:24902376 NA 0.31 6.24 0.32 1.3e-9 Obesity-related traits; LIHC cis rs801193 1.000 rs7782320 chr7:66177098 C/T cg11764359 chr7:65958608 NA 0.71 10.67 0.5 3.78e-23 Aortic root size; LIHC cis rs12824058 0.767 rs4759654 chr12:130815559 A/G cg24838063 chr12:130822603 PIWIL1 0.67 9.97 0.47 9.99e-21 Menopause (age at onset); LIHC cis rs7772486 0.754 rs6921073 chr6:146144377 G/A cg05347473 chr6:146136440 FBXO30 0.37 6.14 0.32 2.28e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs72781680 0.752 rs12616649 chr2:23890913 G/A cg08917208 chr2:24149416 ATAD2B 1.03 8.34 0.41 1.84e-15 Lymphocyte counts; LIHC cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg12756686 chr19:29218302 NA 0.44 6.8 0.35 4.58e-11 Methadone dose in opioid dependence; LIHC trans rs4843747 0.636 rs11864872 chr16:88105966 A/G cg26811252 chr16:29126840 RRN3P2 0.42 6.87 0.35 3.01e-11 Menopause (age at onset); LIHC cis rs1538970 1.000 rs7417107 chr1:45831915 G/C cg24296786 chr1:45957014 TESK2 -0.5 -7.5 -0.38 5.41e-13 Platelet count; LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.97 -0.31 5.99e-9 Total body bone mineral density; LIHC cis rs13108904 0.846 rs4045131 chr4:1228797 A/G cg13395646 chr4:1353034 KIAA1530 -0.56 -7.85 -0.39 5.58e-14 Obesity-related traits; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg14671364 chr1:107599128 PRMT6 0.48 7.18 0.36 4.37e-12 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs35306767 0.671 rs11253473 chr10:906826 A/G cg26597838 chr10:835615 NA 1.17 13.75 0.6 1.47e-34 Eosinophil percentage of granulocytes; LIHC cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg13047869 chr3:10149882 C3orf24 0.53 6.25 0.32 1.25e-9 Alzheimer's disease; LIHC cis rs67311347 1.000 rs7612015 chr3:40399974 A/C cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.46e-9 Renal cell carcinoma; LIHC cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs3096299 0.754 rs3096296 chr16:89411010 C/A cg06640241 chr16:89574553 SPG7 0.5 7.55 0.38 3.91e-13 Multiple myeloma (IgH translocation); LIHC cis rs16958440 0.867 rs79285649 chr18:44699019 A/T cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs3809863 0.602 rs6504833 chr17:45396087 A/G cg25173405 chr17:45401733 C17orf57 -0.58 -8.45 -0.42 8.35e-16 Glaucoma (primary open-angle); LIHC cis rs1983891 1.000 rs913074 chr6:41538545 T/C cg20194872 chr6:41519635 FOXP4 0.41 6.36 0.33 6.31e-10 Prostate cancer; LIHC cis rs4728302 0.869 rs6962865 chr7:133599433 T/A cg10665199 chr7:133106180 EXOC4 0.38 6.63 0.34 1.28e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs600806 0.815 rs10858094 chr1:109950858 T/C cg16275483 chr1:110013120 SYPL2 -0.48 -5.95 -0.31 6.81e-9 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.967 rs86755 chr6:167403108 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.04 -0.51 1.98e-24 Crohn's disease; LIHC cis rs2806561 0.695 rs67238799 chr1:23335012 G/A cg12483005 chr1:23474871 LUZP1 0.45 6.88 0.35 2.86e-11 Height; LIHC cis rs1371867 0.875 rs1788174 chr8:101330957 C/G cg06002616 chr8:101225028 SPAG1 0.35 5.94 0.31 6.88e-9 Atrioventricular conduction; LIHC cis rs2066819 1.000 rs2629447 chr12:56700809 G/A cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Psoriasis vulgaris; LIHC cis rs992157 0.835 rs2292555 chr2:219146882 G/C cg00012203 chr2:219082015 ARPC2 -0.82 -13.04 -0.58 7.86e-32 Colorectal cancer; LIHC cis rs6964587 0.843 rs56075286 chr7:91731518 G/A cg17063962 chr7:91808500 NA 1.04 20.61 0.74 6.26e-62 Breast cancer; LIHC cis rs12142240 0.660 rs7520497 chr1:46824919 C/A cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs2439831 0.867 rs2255051 chr15:43846161 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.54 7.26 0.37 2.71e-12 Lung cancer in ever smokers; LIHC cis rs9534288 0.699 rs1409433 chr13:46655501 T/C cg15192986 chr13:46630673 CPB2 -0.45 -6.45 -0.33 3.8e-10 Blood protein levels; LIHC cis rs2991971 1.000 rs9147 chr1:46016687 T/C cg15605315 chr1:45957053 TESK2 0.45 5.95 0.31 6.61e-9 High light scatter reticulocyte count; LIHC cis rs12611088 0.571 rs2305375 chr19:44013260 C/T cg13740135 chr19:44006432 PHLDB3 -0.41 -6.27 -0.32 1.11e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs875971 0.862 rs10278014 chr7:66051264 C/T cg18876405 chr7:65276391 NA -0.34 -6.29 -0.32 9.45e-10 Aortic root size; LIHC cis rs616147 0.627 rs816510 chr3:39472295 G/T cg17944282 chr3:39448217 RPSA -0.42 -5.79 -0.3 1.58e-8 Amyotrophic lateral sclerosis;Amyotrophic lateral sclerosis (sporadic); LIHC cis rs2635047 1.000 rs9304341 chr18:44670263 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.5 6.82 0.35 4.15e-11 Educational attainment; LIHC cis rs2153535 0.580 rs6905237 chr6:8471790 A/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs651907 0.535 rs34263427 chr3:101507805 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.19 0.52 5.5e-25 Colorectal cancer; LIHC cis rs2204008 0.805 rs11522896 chr12:38234427 T/C cg26384229 chr12:38710491 ALG10B 0.87 10.81 0.5 1.21e-23 Bladder cancer; LIHC cis rs1843834 0.505 rs2140508 chr2:225355839 G/T cg22455342 chr2:225449267 CUL3 0.59 8.59 0.42 3.15e-16 IgE levels in asthmatics (D.p. specific); LIHC cis rs10751667 0.961 rs7395928 chr11:952605 T/G cg10932868 chr11:921992 NA 0.35 6.42 0.33 4.59e-10 Alzheimer's disease (late onset); LIHC cis rs4819052 0.788 rs4819051 chr21:46693128 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 11.81 0.54 3.03e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6665290 0.904 rs3795451 chr1:227181923 C/T cg10327440 chr1:227177885 CDC42BPA -1.19 -30.73 -0.86 2.05e-100 Myeloid white cell count; LIHC cis rs7264396 0.635 rs6060692 chr20:34517925 A/T cg04508476 chr20:34239394 CPNE1;RBM12 0.63 10.58 0.5 8.1e-23 Total cholesterol levels; LIHC cis rs2576037 0.523 rs1539881 chr18:44477897 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.78 -0.3 1.68e-8 Personality dimensions; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs3762637 0.941 rs28679619 chr3:122100349 C/A cg24169773 chr3:122142474 KPNA1 -0.48 -9.29 -0.45 1.82e-18 LDL cholesterol levels; LIHC cis rs34172651 0.917 rs12923476 chr16:24798079 G/A cg00152838 chr16:24741724 TNRC6A -0.49 -6.47 -0.33 3.47e-10 Intelligence (multi-trait analysis); LIHC cis rs1789 0.903 rs4616746 chr4:15673098 A/G cg21329975 chr4:15471214 CC2D2A -0.4 -5.99 -0.31 5.2e-9 Blood protein levels; LIHC cis rs34172651 0.517 rs12920774 chr16:24830750 T/C cg04756594 chr16:24857601 SLC5A11 0.61 8.62 0.42 2.48e-16 Intelligence (multi-trait analysis); LIHC cis rs2290416 0.792 rs62522167 chr8:144678034 G/A cg26536354 chr8:144654954 C8orf73 0.56 6.23 0.32 1.35e-9 Attention deficit hyperactivity disorder; LIHC cis rs6964587 0.626 rs4729011 chr7:91515419 G/A cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.22e-24 Breast cancer; LIHC cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg02353165 chr6:42928485 GNMT 0.95 15.38 0.64 6.02e-41 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2243480 1.000 rs778729 chr7:65824419 T/C cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg03264133 chr6:25882463 NA -0.65 -8.07 -0.4 1.22e-14 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.929 rs9358896 chr6:25943197 C/A cg15691649 chr6:25882328 NA -0.39 -6.18 -0.32 1.79e-9 Height; LIHC cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.633 rs3801471 chr7:75696188 T/G cg04592579 chr7:75616294 TMEM120A 0.4 6.83 0.35 3.86e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2576037 0.583 rs1970668 chr18:44523220 A/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.07 -0.36 8.68e-12 Personality dimensions; LIHC cis rs6500637 0.570 rs1049205 chr16:4942099 C/T cg08329684 chr16:4932620 PPL -0.42 -7.28 -0.37 2.37e-12 Cancer; LIHC cis rs60871478 0.786 rs62432898 chr7:826102 G/A cg04727924 chr7:799746 HEATR2 -0.59 -8.06 -0.4 1.3e-14 Cerebrospinal P-tau181p levels; LIHC cis rs1577917 1.000 rs1999852 chr6:86705738 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.77 -0.47 4.66e-20 Response to antipsychotic treatment; LIHC cis rs2637266 1.000 rs2637268 chr10:78332213 G/T cg18941641 chr10:78392320 NA 0.28 5.91 0.3 8.17e-9 Pulmonary function; LIHC cis rs7582720 1.000 rs72934749 chr2:203746816 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs8081395 0.741 rs180519 chr17:58016271 G/A cg13753209 chr17:57696993 CLTC 0.39 5.96 0.31 6.22e-9 White blood cell count; LIHC trans rs783540 0.967 rs34186444 chr15:83287500 A/G cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.71 -0.34 7.92e-11 Schizophrenia; LIHC cis rs6831352 0.918 rs34936974 chr4:100052384 A/G cg12011299 chr4:100065546 ADH4 0.5 9.17 0.44 4.39e-18 Alcohol dependence; LIHC cis rs1986734 0.619 rs13106227 chr4:77418681 G/A cg24201034 chr4:77507246 SHROOM3 -0.38 -6.12 -0.31 2.62e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs9914988 0.943 rs9894335 chr17:27138483 C/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6089584 0.888 rs2892060 chr20:60617955 G/T cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs6089584 0.546 rs4925337 chr20:60637637 T/C cg23262073 chr20:60523788 NA -0.3 -5.98 -0.31 5.6e-9 Body mass index; LIHC trans rs7246657 1.000 rs12709812 chr19:37794850 A/G cg10208301 chr11:6592745 DNHD1 -0.48 -6.4 -0.33 5.06e-10 Coronary artery calcification; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08722720 chr15:34331557 AVEN;CHRM5 0.5 7.07 0.36 8.88e-12 Pancreatic cancer; LIHC cis rs1005277 0.579 rs2505241 chr10:38442421 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.58 -0.5 8.01e-23 Extrinsic epigenetic age acceleration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20930802 chr3:44519333 ZNF445 0.44 6.17 0.32 1.89e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs16828019 0.852 rs71648535 chr1:41613750 G/A cg20697417 chr1:41786797 NA 0.35 6.64 0.34 1.24e-10 Intelligence (multi-trait analysis); LIHC cis rs7534824 0.625 rs58234233 chr1:101510440 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 7.42 0.37 9.55e-13 Refractive astigmatism; LIHC trans rs867371 0.820 rs7164362 chr15:82486742 C/G cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.1 -0.36 7.05e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC trans rs1005277 0.557 rs176887 chr10:38406094 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC trans rs7613875 0.663 rs6762477 chr3:50093209 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.6 -0.34 1.62e-10 Body mass index; LIHC cis rs1005277 0.522 rs1208684 chr10:38093936 G/A cg25427524 chr10:38739819 LOC399744 -0.64 -12.3 -0.55 4.93e-29 Extrinsic epigenetic age acceleration; LIHC cis rs8180040 0.900 rs4858894 chr3:47484953 C/G cg27129171 chr3:47204927 SETD2 0.58 9.98 0.47 9.3e-21 Colorectal cancer; LIHC cis rs9902453 0.967 rs34323226 chr17:28517454 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.1 0.44 7.77e-18 Coffee consumption (cups per day); LIHC cis rs2180341 0.814 rs9401958 chr6:127736357 T/G cg27446573 chr6:127587934 RNF146 0.8 13.32 0.58 6.62e-33 Breast cancer; LIHC cis rs66887589 0.774 rs9307477 chr4:120421809 G/A cg09307838 chr4:120376055 NA 0.5 7.68 0.38 1.7e-13 Diastolic blood pressure; LIHC cis rs7131987 0.903 rs7970390 chr12:29398655 A/G cg12903224 chr12:29470962 FAR2 -0.37 -5.95 -0.31 6.8e-9 QT interval; LIHC cis rs9921222 0.597 rs3848369 chr16:415078 C/T cg00101154 chr16:420108 MRPL28 -0.63 -9.89 -0.47 1.94e-20 Bone mineral density (spine);Bone mineral density; LIHC cis rs2153535 0.542 rs9378553 chr6:8472632 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs4834770 1.000 rs4834771 chr4:120242772 C/A cg09307838 chr4:120376055 NA 0.43 6.5 0.33 2.87e-10 Blood protein levels; LIHC cis rs35110281 0.782 rs4818856 chr21:45043495 A/G cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.42e-23 Mean corpuscular volume; LIHC cis rs8141529 0.515 rs13056243 chr22:29349306 A/G cg15103426 chr22:29168792 CCDC117 -0.43 -6.14 -0.32 2.24e-9 Lymphocyte counts; LIHC cis rs757081 0.643 rs665311 chr11:17206740 A/T cg15432903 chr11:17409602 KCNJ11 -0.43 -5.94 -0.31 7.08e-9 Systolic blood pressure; LIHC trans rs7142002 1.000 rs7142002 chr14:102360745 T/C cg18984499 chr17:8286166 RPL26 0.65 6.19 0.32 1.77e-9 Autism; LIHC cis rs11630290 0.736 rs28621516 chr15:64156314 G/A cg12036633 chr15:63758958 NA -0.64 -6.05 -0.31 3.8e-9 Iris characteristics; LIHC cis rs9556958 0.635 rs4529985 chr13:99167120 G/C cg07423050 chr13:99094983 FARP1 -0.36 -6.17 -0.32 1.96e-9 Educational attainment (years of education); LIHC cis rs9733 0.596 rs72702580 chr1:150691285 A/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg10802521 chr3:52805072 NEK4 -0.46 -7.75 -0.39 1.07e-13 Electroencephalogram traits; LIHC cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg06453172 chr10:134556979 INPP5A -0.62 -7.87 -0.39 4.85e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg13047869 chr3:10149882 C3orf24 0.48 5.89 0.3 9.41e-9 Alzheimer's disease; LIHC cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg22168489 chr12:122356033 WDR66 0.37 5.87 0.3 1.04e-8 Mean corpuscular volume; LIHC cis rs1185460 1.000 rs7127212 chr11:118953202 A/G cg23280166 chr11:118938394 VPS11 -0.51 -6.58 -0.34 1.81e-10 Coronary artery disease; LIHC cis rs3736594 0.840 rs57238885 chr2:27974260 C/G cg27432699 chr2:27873401 GPN1 0.41 6.44 0.33 4.13e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs10911232 0.507 rs4369195 chr1:182996291 G/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.14 0.48 2.62e-21 Hypertriglyceridemia; LIHC cis rs7249142 0.563 rs11669860 chr19:19277296 G/A cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.39 -6.32 -0.32 8.34e-10 IgG glycosylation; LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs317689 0.788 rs317679 chr12:69693172 A/C cg14784868 chr12:69753453 YEATS4 0.6 8.73 0.43 1.17e-16 Response to diuretic therapy; LIHC cis rs6754311 0.731 rs309134 chr2:136755684 A/G cg07305463 chr2:136567211 LCT 0.34 6.61 0.34 1.48e-10 Mosquito bite size; LIHC cis rs4243830 0.850 rs10746502 chr1:6607199 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.87 -11.28 -0.52 2.62e-25 Body mass index; LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs1395 1.000 rs4665958 chr2:27443196 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.4 -5.72 -0.3 2.28e-8 Blood metabolite levels; LIHC cis rs11098699 0.821 rs13109534 chr4:124211262 T/C cg09941581 chr4:124220074 SPATA5 0.32 6.4 0.33 5.2e-10 Mosquito bite size; LIHC cis rs6723226 0.521 rs1991626 chr2:32602450 G/A cg02381751 chr2:32503542 YIPF4 -0.56 -7.78 -0.39 8.94e-14 Intelligence (multi-trait analysis); LIHC cis rs6088580 0.570 rs6058057 chr20:33065283 G/A cg08999081 chr20:33150536 PIGU 0.67 13.33 0.58 6.18e-33 Glomerular filtration rate (creatinine); LIHC cis rs1801251 0.778 rs2250665 chr2:233752639 A/T cg08000102 chr2:233561755 GIGYF2 -0.71 -10.39 -0.49 3.81e-22 Coronary artery disease; LIHC trans rs4906332 0.933 rs35999760 chr14:103924481 A/C cg17675199 chr6:35436792 RPL10A 0.34 6.63 0.34 1.32e-10 Coronary artery disease; LIHC cis rs916888 0.821 rs415430 chr17:44859144 C/T cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs172166 0.637 rs1071893 chr6:28167635 G/C cg23485639 chr6:28045615 ZNF165 0.37 5.89 0.3 9.34e-9 Cardiac Troponin-T levels; LIHC cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.4 0.45 8.31e-19 Bipolar disorder; LIHC cis rs7584330 0.554 rs13405619 chr2:238445661 C/T cg08992911 chr2:238395768 MLPH 0.49 5.96 0.31 6.24e-9 Prostate cancer; LIHC cis rs6782228 0.606 rs6439135 chr3:128358633 G/A cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg03396347 chr1:1875803 NA 0.38 6.39 0.33 5.49e-10 Body mass index; LIHC cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg27297192 chr10:134578999 INPP5A 0.56 8.46 0.42 8.05e-16 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4243830 0.850 rs4908915 chr1:6601607 T/C cg22792644 chr1:6614718 TAS1R1;NOL9 -0.94 -11.92 -0.54 1.22e-27 Body mass index; LIHC cis rs116095464 0.614 rs10067482 chr5:219328 T/G cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs4975616 0.869 rs466502 chr5:1325767 C/T cg06550200 chr5:1325588 CLPTM1L 0.63 10.38 0.49 4.13e-22 Lung cancer; LIHC cis rs2795502 0.873 rs3123753 chr10:43404899 C/T cg27426351 chr10:43362370 NA 0.48 5.81 0.3 1.46e-8 Blood protein levels; LIHC cis rs870825 0.616 rs41278579 chr4:185622402 A/G cg04058563 chr4:185651563 MLF1IP 0.78 7.46 0.37 7.42e-13 Blood protein levels; LIHC cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg11764359 chr7:65958608 NA 0.68 9.31 0.45 1.58e-18 Calcium levels; LIHC cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg11301795 chr4:187892539 NA -0.29 -7.68 -0.38 1.69e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs79057730 0.599 rs35928068 chr7:805363 G/C cg06242242 chr7:766104 PRKAR1B;HEATR2 0.82 9.13 0.44 6.06e-18 Initial pursuit acceleration; LIHC cis rs748404 0.660 rs689767 chr15:43722077 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.14 0.36 5.5e-12 Lung cancer; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg00800038 chr16:89945340 TCF25 -0.6 -9.53 -0.46 3.02e-19 Skin colour saturation; LIHC trans rs11098499 0.863 rs3822190 chr4:120428098 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.4 0.45 8.36e-19 Corneal astigmatism; LIHC cis rs2991971 1.000 rs622798 chr1:46015271 T/G cg15605315 chr1:45957053 TESK2 0.45 5.89 0.3 9.42e-9 High light scatter reticulocyte count; LIHC cis rs5769765 0.542 rs761878 chr22:50249677 A/G cg02269571 chr22:50332266 NA 0.73 8.09 0.4 1.07e-14 Schizophrenia; LIHC trans rs3960554 0.932 rs11975745 chr7:75843524 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 6.91 0.35 2.32e-11 Eotaxin levels; LIHC cis rs8067545 0.611 rs1373146 chr17:20206675 G/A cg13482628 chr17:19912719 NA -0.41 -6.73 -0.34 7.17e-11 Schizophrenia; LIHC cis rs11711311 0.955 rs1048892 chr3:113464859 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.89 -0.35 2.72e-11 IgG glycosylation; LIHC cis rs3106136 0.681 rs28458965 chr4:95302476 A/G cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs67311347 1.000 rs9829800 chr3:40443927 T/C cg09455208 chr3:40491958 NA 0.34 6.82 0.35 4.06e-11 Renal cell carcinoma; LIHC cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg05590025 chr7:65112418 INTS4L2 0.56 6.31 0.32 8.58e-10 Diabetic kidney disease; LIHC cis rs7582720 1.000 rs72934505 chr2:203916487 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9916302 0.800 rs8081220 chr17:37473157 A/C cg00129232 chr17:37814104 STARD3 0.39 6.25 0.32 1.19e-9 Glomerular filtration rate (creatinine); LIHC cis rs7959452 0.590 rs7968629 chr12:69782857 G/A cg14784868 chr12:69753453 YEATS4 0.94 20.36 0.74 6.6e-61 Blood protein levels; LIHC cis rs1034435 0.547 rs743846 chr22:48900819 C/T cg05992904 chr22:48892994 FAM19A5 -0.45 -8.0 -0.4 2e-14 Late-onset Alzheimer's disease; LIHC cis rs8077889 1.000 rs17674998 chr17:41879544 A/G cg26893861 chr17:41843967 DUSP3 0.89 9.87 0.47 2.27e-20 Triglycerides; LIHC cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg19318889 chr4:1322082 MAEA -0.38 -6.16 -0.32 2.01e-9 Obesity-related traits; LIHC cis rs6061231 1.000 rs13043313 chr20:60958269 A/G cg24112000 chr20:60950667 NA -0.63 -9.64 -0.46 1.3e-19 Colorectal cancer; LIHC cis rs6540556 0.723 rs12059226 chr1:209906675 A/G cg05527609 chr1:210001259 C1orf107 -0.54 -7.75 -0.39 1.03e-13 Red blood cell count; LIHC cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg18357526 chr6:26021779 HIST1H4A 0.5 6.95 0.35 1.86e-11 Blood metabolite levels; LIHC cis rs240764 0.645 rs454747 chr6:101055566 T/C cg09795085 chr6:101329169 ASCC3 0.45 6.52 0.33 2.55e-10 Neuroticism; LIHC cis rs9457247 0.510 rs6456151 chr6:167471851 A/C cg12798992 chr6:167411361 FGFR1OP 0.44 6.8 0.34 4.81e-11 Crohn's disease; LIHC cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg03188948 chr7:1209495 NA 0.87 6.27 0.32 1.11e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8177179 0.967 rs9869311 chr3:133451613 C/T cg24879335 chr3:133465180 TF 0.48 11.13 0.52 9.45e-25 Iron status biomarkers (transferrin levels); LIHC cis rs9303401 0.659 rs17222621 chr17:56695923 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC trans rs11098499 0.780 rs7692994 chr4:120427489 C/A cg25214090 chr10:38739885 LOC399744 0.49 8.1 0.4 9.75e-15 Corneal astigmatism; LIHC cis rs2224391 0.910 rs7752203 chr6:5260812 C/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.41 -6.07 -0.31 3.45e-9 Height; LIHC cis rs2274273 0.934 rs10144418 chr14:55817708 T/C cg01864836 chr14:55583639 NA -0.37 -6.55 -0.33 2.18e-10 Protein biomarker; LIHC cis rs926392 0.640 rs7268716 chr20:37693214 C/T cg16355469 chr20:37678765 NA 0.49 7.17 0.36 4.79e-12 Dialysis-related mortality; LIHC cis rs12048904 0.964 rs12027668 chr1:101330984 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.53 8.31 0.41 2.29e-15 Multiple sclerosis; LIHC cis rs79387448 0.638 rs11465670 chr2:103034440 A/G cg09003973 chr2:102972529 NA 1.02 9.18 0.44 4.24e-18 Gut microbiota (bacterial taxa); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26561342 chr1:45241260 SNORD55;RPS8;SNORD46 -0.36 -6.05 -0.31 3.83e-9 Pancreatic cancer; LIHC cis rs9733 0.596 rs11204697 chr1:150658971 C/T cg18016565 chr1:150552671 MCL1 0.59 11.6 0.53 1.9e-26 Tonsillectomy; LIHC cis rs2070488 0.804 rs13085153 chr3:38461279 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.54 0.56 6.16e-30 Electrocardiographic conduction measures; LIHC cis rs7534824 0.543 rs61780295 chr1:101400264 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 7.07 0.36 8.96e-12 Refractive astigmatism; LIHC cis rs354225 0.565 rs2971880 chr2:54885640 A/T cg26097391 chr2:54893211 SPTBN1 0.39 6.18 0.32 1.85e-9 Schizophrenia; LIHC cis rs546131 0.642 rs2956073 chr11:34842883 C/T cg11058730 chr11:34937778 PDHX;APIP 0.65 9.31 0.45 1.64e-18 Lung disease severity in cystic fibrosis; LIHC cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.64 -0.38 2.21e-13 Electroencephalogram traits; LIHC cis rs7131987 0.903 rs10843371 chr12:29414232 G/A cg05697976 chr12:29376483 FAR2 0.31 6.38 0.33 5.76e-10 QT interval; LIHC cis rs909341 0.810 rs2427529 chr20:62359564 T/A cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.74e-11 Atopic dermatitis; LIHC cis rs1144333 0.655 rs4949681 chr1:76409828 C/T cg03433033 chr1:76189801 ACADM 0.54 7.64 0.38 2.14e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs2180341 0.920 rs9398836 chr6:127576497 T/G cg27446573 chr6:127587934 RNF146 0.93 14.8 0.62 1.14e-38 Breast cancer; LIHC cis rs9467773 0.526 rs9688946 chr6:26367445 C/A cg14345882 chr6:26364793 BTN3A2 0.34 5.74 0.3 2.04e-8 Intelligence (multi-trait analysis); LIHC cis rs2380220 0.606 rs4559095 chr6:95994154 A/C cg15832292 chr6:96025679 MANEA 0.59 7.94 0.39 2.92e-14 Behavioural disinhibition (generation interaction); LIHC cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg09323728 chr8:95962352 TP53INP1 -0.3 -6.44 -0.33 4.09e-10 Type 2 diabetes; LIHC cis rs11676348 0.710 rs11894169 chr2:219046846 T/C cg20019365 chr2:219134978 PNKD;AAMP 0.45 5.88 0.3 9.86e-9 Ulcerative colitis; LIHC cis rs17106184 0.786 rs56985406 chr1:50999695 G/A cg07174182 chr1:51127561 FAF1 -0.7 -7.11 -0.36 6.97e-12 Type 2 diabetes; LIHC cis rs11583043 1.000 rs11583043 chr1:101466054 C/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.92 0.31 7.65e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.49 0.53 4.77e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7264396 0.733 rs2425105 chr20:34312834 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.69 -11.98 -0.54 7.21e-28 Total cholesterol levels; LIHC trans rs875971 0.545 rs12670811 chr7:65823019 C/A cg26939375 chr7:64535504 NA 0.4 6.25 0.32 1.24e-9 Aortic root size; LIHC cis rs6964587 0.869 rs11769726 chr7:91485231 A/G cg17063962 chr7:91808500 NA -0.98 -18.24 -0.7 2.17e-52 Breast cancer; LIHC trans rs6934970 1.000 rs6934919 chr6:113124141 G/A cg02462569 chr6:150064036 NUP43 -0.46 -6.09 -0.31 3.1e-9 Bipolar disorder (body mass index interaction); LIHC cis rs2279817 1.000 rs10788681 chr1:18019524 C/A cg21791023 chr1:18019539 ARHGEF10L 0.63 8.57 0.42 3.58e-16 Neuroticism; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg15383120 chr6:291909 DUSP22 -0.48 -6.29 -0.32 9.8e-10 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08804807 chr5:173315313 CPEB4 0.48 6.38 0.33 5.66e-10 Lung function (FEV1/FVC); LIHC cis rs7712401 0.791 rs6872932 chr5:122145636 A/G cg18764291 chr5:122110994 SNX2 0.35 5.99 0.31 5.26e-9 Mean platelet volume; LIHC cis rs72781680 0.948 rs72790326 chr2:24126153 C/T cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC trans rs61931739 0.500 rs11053277 chr12:34553835 T/A cg26384229 chr12:38710491 ALG10B 0.63 8.01 0.4 1.76e-14 Morning vs. evening chronotype; LIHC cis rs9902453 0.704 rs2628179 chr17:28071796 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.68 -11.0 -0.51 2.62e-24 Coffee consumption (cups per day); LIHC cis rs7568498 1.000 rs10164593 chr2:161981972 C/T cg22496339 chr2:162101262 NA -0.53 -6.04 -0.31 4.02e-9 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC trans rs9914544 0.678 rs28374894 chr17:18761659 C/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.8e-10 Educational attainment (years of education); LIHC cis rs79387448 0.745 rs59126438 chr2:103165142 T/G cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs2070488 0.775 rs13072731 chr3:38533335 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.61 0.56 3.24e-30 Electrocardiographic conduction measures; LIHC cis rs523522 0.847 rs11065132 chr12:120908459 C/T cg12219531 chr12:120966889 COQ5 0.65 12.69 0.57 1.71e-30 High light scatter reticulocyte count; LIHC cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg04317338 chr11:64019027 PLCB3 0.87 10.96 0.51 3.84e-24 Mean platelet volume; LIHC cis rs1008375 0.966 rs10939735 chr4:17578891 A/G cg02297831 chr4:17616191 MED28 0.44 6.04 0.31 4.08e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs13088645 0.683 rs9790169 chr3:134151959 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.36 -6.48 -0.33 3.3e-10 Coronary artery disease; LIHC cis rs17685 0.735 rs11763339 chr7:75761541 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17376456 0.569 rs2045021 chr5:93224222 G/A cg25358565 chr5:93447407 FAM172A -0.78 -7.47 -0.37 6.69e-13 Diabetic retinopathy; LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg02034447 chr16:89574710 SPG7 0.48 7.44 0.37 8.18e-13 Multiple myeloma (IgH translocation); LIHC cis rs801193 1.000 rs13239306 chr7:66136017 T/G cg18252515 chr7:66147081 NA 0.44 5.87 0.3 1.05e-8 Aortic root size; LIHC cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg23978390 chr7:1156363 C7orf50 0.61 9.46 0.46 4.98e-19 Longevity;Endometriosis; LIHC trans rs12310956 0.532 rs2171534 chr12:33838998 C/T cg26384229 chr12:38710491 ALG10B 0.46 6.31 0.32 8.86e-10 Morning vs. evening chronotype; LIHC cis rs2191566 0.664 rs4482396 chr19:44562000 C/T cg20607764 chr19:44506953 ZNF230 -0.37 -6.15 -0.32 2.19e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs929354 0.772 rs2051876 chr7:157009037 A/G cg17757837 chr7:157058334 UBE3C -0.73 -12.14 -0.55 1.84e-28 Body mass index; LIHC cis rs11758351 0.518 rs79922979 chr6:26224975 A/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.26 0.37 2.61e-12 Gout;Renal underexcretion gout; LIHC cis rs5769765 0.954 rs910799 chr22:50278568 A/G cg26441486 chr22:50317300 CRELD2 -0.35 -6.1 -0.31 2.9e-9 Schizophrenia; LIHC cis rs875971 0.862 rs11773628 chr7:65982631 G/T cg18876405 chr7:65276391 NA -0.36 -6.53 -0.33 2.39e-10 Aortic root size; LIHC cis rs35306767 0.903 rs11253504 chr10:956046 A/G cg20503657 chr10:835505 NA 1.09 11.36 0.52 1.33e-25 Eosinophil percentage of granulocytes; LIHC cis rs6696846 0.715 rs12139373 chr1:205054879 A/C cg21545522 chr1:205238299 TMCC2 0.31 5.93 0.31 7.3e-9 Red blood cell count; LIHC cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg15691649 chr6:25882328 NA -0.43 -6.27 -0.32 1.06e-9 Blood metabolite levels; LIHC cis rs6088580 0.634 rs6059905 chr20:33126946 T/C cg08999081 chr20:33150536 PIGU 0.68 13.41 0.59 2.94e-33 Glomerular filtration rate (creatinine); LIHC cis rs7208859 0.573 rs73267872 chr17:29067207 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3820068 0.655 rs72645826 chr1:15889741 A/G cg17385448 chr1:15911702 AGMAT 0.41 6.8 0.35 4.65e-11 Systolic blood pressure; LIHC cis rs9549367 0.826 rs9549710 chr13:113898064 A/C cg00898013 chr13:113819073 PROZ -0.43 -7.4 -0.37 1.06e-12 Platelet distribution width; LIHC cis rs826838 1.000 rs7953227 chr12:38946193 G/A cg26384229 chr12:38710491 ALG10B 0.95 13.09 0.58 5.31e-32 Heart rate; LIHC cis rs6840360 0.868 rs6823462 chr4:152708740 G/A cg22705602 chr4:152727874 NA -0.34 -7.31 -0.37 1.86e-12 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.528 rs115553816 chr2:136692893 G/A cg07305463 chr2:136567211 LCT -0.38 -5.9 -0.3 8.86e-9 Corneal structure; LIHC cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg16405210 chr4:1374714 KIAA1530 -0.94 -15.9 -0.65 5.45e-43 Longevity; LIHC cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs11190604 1.000 rs1080698 chr10:102295114 G/T cg07080220 chr10:102295463 HIF1AN 0.56 8.13 0.4 8.07e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3768617 0.510 rs3765521 chr1:183077615 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.29 0.49 8.41e-22 Fuchs's corneal dystrophy; LIHC cis rs473651 0.935 rs508483 chr2:239339709 T/C cg21699342 chr2:239360505 ASB1 0.34 6.66 0.34 1.12e-10 Multiple system atrophy; LIHC cis rs4555082 0.681 rs28588570 chr14:105709606 A/T cg13114125 chr14:105738426 BRF1 -0.71 -9.8 -0.47 3.75e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs2180341 1.000 rs2326567 chr6:127606160 G/A cg27446573 chr6:127587934 RNF146 1.02 15.66 0.65 4.93e-42 Breast cancer; LIHC cis rs6570726 0.599 rs4398765 chr6:145935006 C/A cg23711669 chr6:146136114 FBXO30 0.62 8.97 0.44 1.95e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg08859206 chr1:53392774 SCP2 0.35 5.83 0.3 1.26e-8 Monocyte count; LIHC cis rs2645424 0.635 rs6980952 chr8:11716473 C/G cg21281001 chr8:11725306 CTSB -0.47 -7.48 -0.38 6.26e-13 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); LIHC cis rs11030122 0.702 rs66503725 chr11:3980998 G/A cg18678763 chr11:4115507 RRM1 -0.58 -8.56 -0.42 3.86e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs56104184 0.779 rs17206686 chr19:49356317 A/G cg15549821 chr19:49342101 PLEKHA4 -0.93 -9.34 -0.45 1.29e-18 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs6951245 0.832 rs10266519 chr7:1142977 C/T cg24642844 chr7:1081250 C7orf50 -0.72 -7.59 -0.38 3.17e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9549367 0.865 rs9549366 chr13:113907644 G/A cg18105134 chr13:113819100 PROZ -0.58 -10.29 -0.49 8.43e-22 Platelet distribution width; LIHC trans rs9929218 0.954 rs35794312 chr16:68827785 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -7.99 -0.4 2.03e-14 Colorectal cancer; LIHC cis rs9420 0.961 rs1647405 chr11:57477889 C/T cg19752551 chr11:57585705 CTNND1 -0.51 -7.25 -0.36 2.89e-12 Schizophrenia; LIHC cis rs798554 0.660 rs2283783 chr7:2855326 G/A cg13628971 chr7:2884303 GNA12 0.43 6.68 0.34 9.42e-11 Height; LIHC cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg18876405 chr7:65276391 NA -0.55 -9.31 -0.45 1.65e-18 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06514377 chr2:3320918 TSSC1 0.41 6.05 0.31 3.76e-9 Pancreatic cancer; LIHC cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs523522 0.962 rs12371550 chr12:120987643 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.9 0.54 1.53e-27 High light scatter reticulocyte count; LIHC cis rs17685 0.623 rs7782808 chr7:75768645 C/T cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10463316 0.894 rs869196 chr5:150746287 G/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.51 -0.33 2.67e-10 Metabolite levels (Pyroglutamine); LIHC cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg20607798 chr8:58055168 NA 0.48 6.01 0.31 4.7e-9 Developmental language disorder (linguistic errors); LIHC cis rs16958440 0.867 rs59217333 chr18:44694844 A/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg22800045 chr5:56110881 MAP3K1 0.69 8.8 0.43 6.79e-17 Initial pursuit acceleration; LIHC trans rs5756813 0.635 rs11089856 chr22:38205784 A/C cg19894588 chr14:64061835 NA -0.68 -10.14 -0.48 2.71e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs875971 0.862 rs6460293 chr7:65810192 C/A cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs9457247 1.000 rs376574 chr6:167389956 A/T cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs11955398 0.647 rs57521726 chr5:59984897 A/T cg02684056 chr5:59996105 DEPDC1B 0.44 6.25 0.32 1.23e-9 Intelligence (multi-trait analysis); LIHC cis rs10911251 0.508 rs10797854 chr1:183106739 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.3 0.49 7.65e-22 Colorectal cancer; LIHC cis rs9733 0.596 rs12089731 chr1:150647798 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs9457247 1.000 rs1794693 chr6:167405670 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC cis rs1707322 0.721 rs10890336 chr1:46111056 C/T cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs78049276 0.736 rs72957606 chr4:148400011 A/G cg13149281 chr14:23389818 RBM23;PRMT5 -0.59 -7.79 -0.39 8.15e-14 Pulse pressure; LIHC cis rs2933343 0.621 rs789241 chr3:128585752 G/A cg25356066 chr3:128598488 ACAD9 0.55 7.57 0.38 3.47e-13 IgG glycosylation; LIHC cis rs11711311 1.000 rs16861312 chr3:113492402 G/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.13 0.44 6.13e-18 IgG glycosylation; LIHC cis rs7208859 0.673 rs9896095 chr17:29187497 A/G cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg10862848 chr6:42927986 GNMT 0.29 6.71 0.34 8.2e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.69 11.52 0.53 3.69e-26 Prudent dietary pattern; LIHC cis rs1816752 0.870 rs7981480 chr13:25015104 A/G cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC trans rs17513961 1.000 rs17513961 chr7:46392567 G/T cg26298814 chr3:33259889 SUSD5 0.66 6.12 0.31 2.59e-9 Treatment response for severe sepsis; LIHC cis rs2637266 1.000 rs7475686 chr10:78358761 T/C cg18941641 chr10:78392320 NA 0.27 5.71 0.3 2.42e-8 Pulmonary function; LIHC cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg01518246 chr11:63870912 FLRT1;MACROD1 0.42 5.89 0.3 9.46e-9 Mean platelet volume; LIHC cis rs8044995 0.706 rs111948678 chr16:68255959 G/A cg05110241 chr16:68378359 PRMT7 -0.61 -6.77 -0.34 5.71e-11 Schizophrenia; LIHC cis rs8017423 0.935 rs9944124 chr14:90791501 T/C cg04374321 chr14:90722782 PSMC1 0.69 12.86 0.57 3.85e-31 Mortality in heart failure; LIHC cis rs4407350 0.967 rs4522715 chr22:44922347 G/A cg26276947 chr22:44892394 LDOC1L 0.35 6.35 0.32 6.81e-10 Intelligence (multi-trait analysis); LIHC cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg06634786 chr22:41940651 POLR3H 0.74 7.74 0.39 1.13e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4478037 0.822 rs9883177 chr3:33123354 T/C cg27203090 chr3:33138513 GLB1;TMPPE -0.52 -6.51 -0.33 2.6e-10 Major depressive disorder; LIHC cis rs4742903 0.935 rs17237053 chr9:106946359 C/T cg14250997 chr9:106856677 SMC2 -0.37 -6.44 -0.33 4.12e-10 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1348850 0.558 rs4337505 chr2:178529714 A/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.57 7.42 0.37 9.56e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06943149 chr12:77157476 ZDHHC17 0.39 6.56 0.33 2.02e-10 Cognitive function; LIHC cis rs4474465 0.850 rs7111004 chr11:78269961 G/A cg27205649 chr11:78285834 NARS2 0.39 5.94 0.31 7.15e-9 Alzheimer's disease (survival time); LIHC cis rs9291683 0.655 rs35750364 chr4:10049049 T/C cg11266682 chr4:10021025 SLC2A9 0.35 7.44 0.37 8.29e-13 Bone mineral density; LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg24209194 chr3:40518798 ZNF619 0.63 9.71 0.46 7.86e-20 Renal cell carcinoma; LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg07677032 chr17:61819896 STRADA 0.44 6.42 0.33 4.45e-10 Prudent dietary pattern; LIHC cis rs9910055 0.530 rs2269905 chr17:42294462 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.64 9.37 0.45 1e-18 Total body bone mineral density; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.27 0.41 3.07e-15 Height; LIHC trans rs7395662 0.504 rs11039701 chr11:48389838 A/G cg15704280 chr7:45808275 SEPT13 -0.42 -6.35 -0.32 6.87e-10 HDL cholesterol; LIHC cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg18279126 chr7:2041391 MAD1L1 0.37 5.74 0.3 2.12e-8 Bipolar disorder and schizophrenia; LIHC cis rs11229555 0.645 rs12283414 chr11:58176920 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg10360323 chr17:41437877 NA 0.4 5.97 0.31 5.82e-9 Menopause (age at onset); LIHC cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg11502198 chr6:26597334 ABT1 0.65 10.29 0.49 7.96e-22 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg08280861 chr8:58055591 NA 0.5 6.1 0.31 2.89e-9 Developmental language disorder (linguistic errors); LIHC cis rs10870270 0.917 rs11146417 chr10:133791034 C/G cg17892150 chr10:133769511 PPP2R2D -0.67 -12.05 -0.55 4.29e-28 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2019216 0.967 rs1877500 chr17:21886233 T/C cg22648282 chr17:21454238 C17orf51 -0.34 -5.83 -0.3 1.31e-8 Pelvic organ prolapse; LIHC cis rs10949834 0.793 rs810534 chr7:73505045 A/G cg07137043 chr7:73588983 EIF4H 0.56 6.15 0.32 2.11e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs25645 0.771 rs10445310 chr17:38205396 C/A cg17344932 chr17:38183730 MED24;SNORD124 0.76 14.27 0.61 1.37e-36 Myeloid white cell count; LIHC cis rs6430585 0.528 rs309123 chr2:136761175 C/G cg25344623 chr2:136566232 LCT -0.33 -5.71 -0.3 2.4e-8 Corneal structure; LIHC cis rs28829049 0.570 rs12060125 chr1:19391108 A/G cg13387374 chr1:19411106 UBR4 -0.37 -5.82 -0.3 1.36e-8 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs7089973 0.624 rs1359080 chr10:116582419 C/A cg03647239 chr10:116582469 FAM160B1 0.42 6.18 0.32 1.87e-9 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1552244 0.882 rs13077641 chr3:10022935 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs7542091 0.704 rs1108628 chr1:210041150 A/G cg23283495 chr1:209979779 IRF6 0.36 6.09 0.31 3.01e-9 Monobrow; LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs943466 1.000 rs943466 chr6:33731787 A/G cg25922239 chr6:33757077 LEMD2 0.43 6.02 0.31 4.52e-9 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs6665290 0.935 rs17600627 chr1:227201449 A/G cg10327440 chr1:227177885 CDC42BPA -1.15 -28.58 -0.84 1.21e-92 Myeloid white cell count; LIHC cis rs7959452 0.535 rs2305641 chr12:69646914 C/T cg22834771 chr12:69754056 YEATS4 -0.47 -8.2 -0.41 5.05e-15 Blood protein levels; LIHC cis rs7615952 0.688 rs12638224 chr3:125541320 C/T cg05084668 chr3:125655381 ALG1L -0.35 -6.34 -0.32 7.18e-10 Blood pressure (smoking interaction); LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg00800038 chr16:89945340 TCF25 -0.6 -9.78 -0.47 4.42e-20 Skin colour saturation; LIHC cis rs526821 0.595 rs608964 chr11:55339266 G/A cg04317927 chr11:55418816 OR4S2 0.47 8.99 0.44 1.66e-17 Pediatric bone mineral density (spine); LIHC cis rs709400 0.526 rs11622473 chr14:103979762 G/A cg26031613 chr14:104095156 KLC1 0.92 9.22 0.45 3.22e-18 Body mass index; LIHC cis rs2204008 0.774 rs2387811 chr12:38369794 C/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 2.97e-23 Bladder cancer; LIHC cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg11764359 chr7:65958608 NA 0.58 5.98 0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs4474465 1.000 rs7950756 chr11:78157309 A/G cg27205649 chr11:78285834 NARS2 -0.37 -5.74 -0.3 2.12e-8 Alzheimer's disease (survival time); LIHC cis rs898097 0.812 rs55794221 chr17:80849003 G/A cg15664640 chr17:80829946 TBCD -0.78 -12.84 -0.57 4.6e-31 Breast cancer; LIHC trans rs11098499 0.754 rs17049949 chr4:120255290 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.26 0.41 3.23e-15 Corneal astigmatism; LIHC cis rs599083 0.573 rs3018713 chr11:68390986 A/G cg20283391 chr11:68216788 NA -0.38 -5.95 -0.31 6.45e-9 Bone mineral density (spine); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03802069 chr3:137482593 SOX14 0.44 6.07 0.31 3.45e-9 Lung function (FEV1/FVC); LIHC cis rs1577917 0.958 rs12209259 chr6:86502348 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -7.98 -0.4 2.2e-14 Response to antipsychotic treatment; LIHC cis rs12594515 1.000 rs8038058 chr15:45990272 C/T cg19682013 chr15:45996608 NA 0.42 7.31 0.37 1.95e-12 Waist circumference;Weight; LIHC cis rs4665809 0.838 rs2243834 chr2:26357748 A/C cg04944784 chr2:26401820 FAM59B 0.64 8.51 0.42 5.41e-16 Gut microbiome composition (summer); LIHC cis rs2257205 0.667 rs75982345 chr17:56708836 T/C cg12560992 chr17:57184187 TRIM37 0.63 6.1 0.31 2.94e-9 Pancreatic cancer; LIHC cis rs6860806 0.531 rs274556 chr5:131722075 A/G cg24060327 chr5:131705240 SLC22A5 0.81 12.51 0.56 7.67e-30 Breast cancer; LIHC cis rs7520050 0.931 rs11211213 chr1:46342517 G/A cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7408868 1.000 rs7245814 chr19:15274503 A/G cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg25072359 chr17:41440525 NA 0.38 6.03 0.31 4.34e-9 Menopause (age at onset); LIHC cis rs9790314 0.967 rs460165 chr3:161087710 G/A cg04691961 chr3:161091175 C3orf57 -0.45 -7.13 -0.36 6.15e-12 Morning vs. evening chronotype; LIHC cis rs7258465 1.000 rs10409483 chr19:18590223 C/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC trans rs877282 0.755 rs2486579 chr10:785647 G/A cg22713356 chr15:30763199 NA 1.21 11.49 0.53 4.56e-26 Uric acid levels; LIHC cis rs7296418 0.961 rs10848428 chr12:123572495 C/T cg06742321 chr12:123595122 PITPNM2 0.32 6.02 0.31 4.43e-9 Platelet count; LIHC cis rs3767633 0.925 rs1553444 chr1:161813515 C/T cg09175582 chr1:161736000 ATF6 0.53 5.73 0.3 2.21e-8 IgG glycosylation; LIHC cis rs6499255 1.000 rs60231938 chr16:69830415 G/A cg15192750 chr16:69999425 NA 0.44 6.73 0.34 7.17e-11 IgE levels; LIHC cis rs9811920 0.638 rs1688782 chr3:99630527 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 6.61 0.34 1.49e-10 Axial length; LIHC cis rs2070488 0.560 rs1381798 chr3:38437471 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.57 -7.84 -0.39 5.92e-14 Electrocardiographic conduction measures; LIHC cis rs2380220 0.541 rs9285413 chr6:96023439 G/A cg15832292 chr6:96025679 MANEA 0.7 8.71 0.43 1.32e-16 Behavioural disinhibition (generation interaction); LIHC cis rs4716602 0.596 rs12698432 chr7:156158719 C/G cg16983916 chr7:156159713 NA 0.32 5.87 0.3 1.02e-8 Anti-saccade response; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02711724 chr8:130877076 FAM49B -0.42 -6.05 -0.31 3.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs16958440 0.867 rs58061761 chr18:44686165 T/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg23205692 chr1:25664452 TMEM50A -0.37 -5.83 -0.3 1.27e-8 Erythrocyte sedimentation rate; LIHC cis rs7572733 0.515 rs11891555 chr2:198853540 G/T cg00792783 chr2:198669748 PLCL1 0.42 6.11 0.31 2.67e-9 Dermatomyositis; LIHC cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg22800045 chr5:56110881 MAP3K1 0.67 8.56 0.42 4e-16 Initial pursuit acceleration; LIHC trans rs1973993 0.691 rs11165623 chr1:96893000 G/A cg10631902 chr5:14652156 NA 0.37 9.92 0.47 1.47e-20 Weight; LIHC cis rs10876993 0.928 rs2640629 chr12:58065448 C/T cg15848620 chr12:58087721 OS9 -0.52 -7.08 -0.36 8.2e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg19635926 chr16:89946313 TCF25 0.56 7.48 0.37 6.53e-13 Skin colour saturation; LIHC cis rs10197940 0.624 rs13393122 chr2:152413315 A/G cg19508488 chr2:152266495 RIF1 0.59 8.45 0.42 8.27e-16 Lung cancer; LIHC cis rs67311347 1.000 rs11716675 chr3:40485280 G/T cg09455208 chr3:40491958 NA 0.36 7.4 0.37 1.09e-12 Renal cell carcinoma; LIHC cis rs6754311 0.513 rs1438304 chr2:136503157 A/G cg15123519 chr2:136567270 LCT 0.44 8.69 0.43 1.48e-16 Mosquito bite size; LIHC cis rs72627509 0.680 rs3733309 chr4:57857188 A/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.63 -9.05 -0.44 1.11e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg19155557 chr3:41240643 CTNNB1 0.53 7.04 0.36 1.07e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs240764 0.853 rs2062634 chr6:101002618 G/C cg09795085 chr6:101329169 ASCC3 -0.47 -6.22 -0.32 1.43e-9 Neuroticism; LIHC cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.76 0.34 6.09e-11 Gut microbiome composition (summer); LIHC trans rs2739330 0.760 rs5751760 chr22:24243573 G/A cg06437703 chr8:37914619 EIF4EBP1 -0.58 -8.6 -0.42 2.94e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs798554 0.797 rs1182174 chr7:2875420 G/A cg19717773 chr7:2847554 GNA12 -0.43 -6.53 -0.33 2.4e-10 Height; LIHC cis rs7772486 0.597 rs9285508 chr6:146262697 G/T cg05347473 chr6:146136440 FBXO30 -0.48 -6.84 -0.35 3.7e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs13064411 0.696 rs6773497 chr3:113186514 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.11e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs7903847 0.642 rs7078004 chr10:99140511 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7249142 0.562 rs10418053 chr19:19287164 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.63 -0.34 1.29e-10 IgG glycosylation; LIHC cis rs28830936 1.000 rs11632424 chr15:42095351 G/A cg17847044 chr15:42102381 MAPKBP1 -0.33 -6.66 -0.34 1.07e-10 Diastolic blood pressure; LIHC cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.88 0.3 9.86e-9 Menopause (age at onset); LIHC cis rs769267 0.965 rs12460764 chr19:19431963 G/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.39 -0.33 5.54e-10 Tonsillectomy; LIHC cis rs921968 0.612 rs4674323 chr2:219517088 T/C cg02985541 chr2:219472218 PLCD4 0.43 7.91 0.39 3.66e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.520 rs55967509 chr8:57992448 A/G cg02290350 chr8:58132656 NA 0.33 7.04 0.36 1.06e-11 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg10360323 chr17:41437877 NA 0.4 6.08 0.31 3.29e-9 Menopause (age at onset); LIHC cis rs7914558 0.966 rs1890185 chr10:104748718 A/G cg15744005 chr10:104629667 AS3MT -0.4 -9.21 -0.45 3.25e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs16837677 1.000 rs78365002 chr1:156716689 G/A cg19377421 chr1:156697041 ISG20L2;C1orf66 0.63 6.23 0.32 1.37e-9 Sjögren's syndrome; LIHC cis rs116095464 0.558 rs7714335 chr5:263513 T/C cg22857025 chr5:266934 NA -1.54 -18.33 -0.7 9.37e-53 Breast cancer; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg10150615 chr22:24372951 LOC391322 -0.6 -8.85 -0.43 4.8e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2836950 0.545 rs2836956 chr21:40623018 C/G cg11890956 chr21:40555474 PSMG1 0.41 6.56 0.33 1.94e-10 Menarche (age at onset); LIHC cis rs801193 1.000 rs2707856 chr7:66211010 A/T cg00343986 chr7:65444356 GUSB 0.41 6.1 0.31 2.84e-9 Aortic root size; LIHC cis rs9303401 0.659 rs17822908 chr17:56801778 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs7772486 0.846 rs7755440 chr6:146375906 T/C cg05347473 chr6:146136440 FBXO30 0.37 6.05 0.31 3.78e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg21016266 chr12:122356598 WDR66 -0.51 -8.4 -0.41 1.18e-15 Mean corpuscular volume; LIHC cis rs1816752 0.905 rs4770666 chr13:24989029 T/C cg22771759 chr13:24902376 NA 0.33 6.66 0.34 1.1e-10 Obesity-related traits; LIHC cis rs7089973 0.604 rs11196932 chr10:116584386 C/T cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1448094 0.512 rs7970842 chr12:86243258 C/T cg02569458 chr12:86230093 RASSF9 0.47 6.36 0.33 6.47e-10 Major depressive disorder; LIHC cis rs1707322 0.752 rs3811435 chr1:46125790 C/A cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs16828019 0.852 rs12742379 chr1:41526381 A/G cg03962019 chr1:41807865 NA 0.5 7.34 0.37 1.53e-12 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.740 rs9353320 chr6:86244848 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.66 0.34 1.12e-10 Response to antipsychotic treatment; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg06873352 chr17:61820015 STRADA 0.75 13.24 0.58 1.32e-32 Prudent dietary pattern; LIHC cis rs7267979 0.966 rs6050532 chr20:25308793 A/T cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.72 -0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.44e-8 Alzheimer's disease; LIHC cis rs2549003 1.000 rs2549007 chr5:131826875 T/C cg21138405 chr5:131827807 IRF1 -0.4 -10.47 -0.49 1.96e-22 Asthma (sex interaction); LIHC cis rs11105298 0.891 rs10858879 chr12:89886578 A/T cg08166232 chr12:89918718 WDR51B;GALNT4 0.61 6.99 0.35 1.48e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs6442522 0.640 rs2655258 chr3:15525894 A/G cg16303742 chr3:15540471 COLQ 0.4 6.4 0.33 5.05e-10 Uric acid levels; LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs12220238 1.000 rs2395077 chr10:75932001 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.71 6.78 0.34 5.19e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC cis rs3736594 0.546 rs965813 chr2:27789861 T/A cg27432699 chr2:27873401 GPN1 0.46 6.84 0.35 3.7e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2797685 1.000 rs2797685 chr1:7879063 C/T cg04725166 chr1:7887271 PER3 -0.39 -6.89 -0.35 2.61e-11 Crohn's disease; LIHC cis rs2576037 0.796 rs2576043 chr18:44573476 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.51 -7.68 -0.38 1.64e-13 Personality dimensions; LIHC cis rs12594515 0.967 rs11856523 chr15:45989495 C/T cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs2257205 0.667 rs7342841 chr17:56916156 G/A cg05425664 chr17:57184151 TRIM37 -0.61 -6.67 -0.34 1.05e-10 Pancreatic cancer; LIHC cis rs3008870 0.755 rs2815362 chr1:67496803 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.66 11.22 0.52 4.19e-25 Lymphocyte percentage of white cells; LIHC cis rs4820539 0.902 rs4822359 chr22:23474972 A/G cg21100191 chr22:23484243 RTDR1 0.91 16.75 0.67 2.13e-46 Bone mineral density; LIHC cis rs35110281 0.744 rs162395 chr21:44945759 T/C cg21573476 chr21:45109991 RRP1B -0.51 -9.23 -0.45 2.91e-18 Mean corpuscular volume; LIHC cis rs9911578 0.967 rs4932693 chr17:57110327 T/C cg05425664 chr17:57184151 TRIM37 0.59 8.76 0.43 9.33e-17 Intelligence (multi-trait analysis); LIHC trans rs867371 1.000 rs8042464 chr15:82465536 A/G cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.05 -0.36 1e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7116495 1.000 rs517837 chr11:71802359 A/G cg26138937 chr11:71823887 C11orf51 -0.77 -7.42 -0.37 9.42e-13 Severe influenza A (H1N1) infection; LIHC cis rs17854409 0.881 rs1046784 chr20:61472808 G/C cg05147244 chr20:61493195 TCFL5 1.23 11.09 0.51 1.24e-24 Obesity-related traits; LIHC cis rs10751667 0.557 rs4077531 chr11:1013167 G/A ch.11.42038R chr11:967971 AP2A2 0.59 10.79 0.5 1.45e-23 Alzheimer's disease (late onset); LIHC cis rs10242455 0.571 rs41279866 chr7:99315276 C/T cg18809830 chr7:99032528 PTCD1 -0.86 -6.72 -0.34 7.74e-11 Blood metabolite levels; LIHC cis rs2153535 0.580 rs2184586 chr6:8474182 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.23 0.55 9.21e-29 Motion sickness; LIHC cis rs4888262 0.526 rs8055803 chr16:74615190 A/G cg01733217 chr16:74700730 RFWD3 0.83 16.09 0.66 9.46e-44 Testicular germ cell tumor; LIHC cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg19318889 chr4:1322082 MAEA 0.46 6.48 0.33 3.24e-10 Obesity-related traits; LIHC cis rs8081395 0.603 rs1292047 chr17:57955166 C/T cg02344993 chr17:57696989 CLTC 0.45 7.54 0.38 4.26e-13 White blood cell count; LIHC cis rs875971 1.000 rs778696 chr7:65870813 C/G cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs12477438 1.000 rs12466388 chr2:99916538 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.91 -11.09 -0.51 1.23e-24 Chronic sinus infection; LIHC trans rs11098499 0.954 rs10006525 chr4:120408931 T/G cg25214090 chr10:38739885 LOC399744 0.58 9.58 0.46 2.02e-19 Corneal astigmatism; LIHC cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg25364880 chr3:44379878 C3orf23 0.52 7.06 0.36 9.51e-12 Depressive symptoms; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg27411370 chr8:25316735 KCTD9;CDCA2 -0.5 -6.14 -0.32 2.33e-9 Preeclampsia; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 23.89 0.79 6.71e-75 Prudent dietary pattern; LIHC cis rs7927592 0.956 rs11228277 chr11:68308324 G/A cg16797656 chr11:68205561 LRP5 0.53 8.67 0.42 1.73e-16 Total body bone mineral density; LIHC cis rs507080 0.961 rs660489 chr11:118549964 C/A cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC cis rs10911232 0.507 rs10797814 chr1:182990929 C/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.41 0.49 3.07e-22 Hypertriglyceridemia; LIHC cis rs2153535 0.526 rs9406179 chr6:8538224 G/A cg07606381 chr6:8435919 SLC35B3 0.77 11.11 0.51 1.11e-24 Motion sickness; LIHC cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.09e-10 Bipolar disorder; LIHC cis rs3849570 0.925 rs7641973 chr3:81910489 G/A cg07356753 chr3:81810745 GBE1 -0.55 -8.61 -0.42 2.76e-16 Waist circumference;Body mass index; LIHC trans rs6489882 0.902 rs1981557 chr12:113372866 G/C cg10175203 chr3:128143634 NA 0.38 6.19 0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC cis rs801193 0.967 rs34356500 chr7:66236607 G/T cg18876405 chr7:65276391 NA 0.42 7.22 0.36 3.35e-12 Aortic root size; LIHC trans rs4596713 0.507 rs9314865 chr9:71801495 A/G cg16512924 chr15:28394682 HERC2 0.38 6.17 0.32 1.94e-9 Headache; LIHC cis rs17685 0.753 rs1859791 chr7:75786043 T/C cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25216538 chr4:6925470 TBC1D14 0.44 6.82 0.35 4.07e-11 Bilirubin levels; LIHC cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg12463550 chr7:65579703 CRCP 0.69 7.12 0.36 6.23e-12 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg08280861 chr8:58055591 NA 0.49 6.17 0.32 1.9e-9 Developmental language disorder (linguistic errors); LIHC cis rs208520 1.000 rs208535 chr6:66962286 G/A cg07460842 chr6:66804631 NA -0.65 -7.0 -0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs11030122 0.702 rs10767715 chr11:3951409 G/T cg18678763 chr11:4115507 RRM1 -0.58 -8.57 -0.42 3.57e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs68170813 0.559 rs12536491 chr7:106978024 T/G cg02696742 chr7:106810147 HBP1 -0.5 -5.86 -0.3 1.08e-8 Coronary artery disease; LIHC cis rs7613875 0.641 rs2624845 chr3:50062437 C/A cg05623727 chr3:50126028 RBM5 -0.34 -5.89 -0.3 9.2e-9 Body mass index; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs72634258 0.503 rs707457 chr1:7831064 C/A cg00864860 chr1:7907996 UTS2 0.61 5.89 0.3 9.21e-9 Inflammatory bowel disease; LIHC cis rs9381040 0.674 rs3747742 chr6:41162518 C/T cg04346459 chr6:41068666 NFYA;LOC221442 0.41 6.58 0.34 1.81e-10 Alzheimer's disease (late onset); LIHC cis rs2404602 0.684 rs8037847 chr15:76856551 C/T cg23625390 chr15:77176239 SCAPER -0.54 -8.96 -0.44 2.11e-17 Blood metabolite levels; LIHC cis rs4700695 0.925 rs4700693 chr5:65399078 A/G cg21114390 chr5:65439923 SFRS12 -0.46 -6.06 -0.31 3.66e-9 Facial morphology (factor 19); LIHC trans rs67539049 1.000 rs73546312 chr8:11302709 G/A cg21071117 chr11:124747075 ROBO3 -0.38 -6.14 -0.32 2.33e-9 Itch intensity from mosquito bite; LIHC cis rs3814113 0.586 rs10962662 chr9:16889937 C/A cg13173848 chr9:16870893 BNC2 -0.71 -8.69 -0.43 1.48e-16 Epithelial ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer; LIHC cis rs1853665 0.623 rs56363137 chr6:150287154 G/C cg16301758 chr6:150275521 NA -0.46 -6.31 -0.32 8.66e-10 Radiation response; LIHC cis rs858239 0.601 rs4440529 chr7:23168751 G/C cg23682824 chr7:23144976 KLHL7 0.39 5.83 0.3 1.26e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg18252515 chr7:66147081 NA -1.24 -16.13 -0.66 6.34e-44 Diabetic kidney disease; LIHC cis rs9640161 0.636 rs56190213 chr7:150025720 T/C cg10018233 chr7:150070692 REPIN1 0.55 8.5 0.42 5.96e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs317689 0.702 rs544696 chr12:69749939 T/C cg22834771 chr12:69754056 YEATS4 -0.45 -7.29 -0.37 2.19e-12 Response to diuretic therapy; LIHC cis rs2228479 0.557 rs34420680 chr16:89809171 C/T cg00800038 chr16:89945340 TCF25 -0.61 -8.88 -0.43 3.78e-17 Skin colour saturation; LIHC cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg06466757 chr4:1255808 NA 0.35 5.88 0.3 1e-8 Obesity-related traits; LIHC cis rs7072216 0.763 rs10748730 chr10:100171440 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs10916814 0.610 rs4655223 chr1:20901688 C/G cg24502330 chr1:20914028 CDA -0.32 -6.85 -0.35 3.52e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24583131 chr6:18265189 DEK 0.43 6.71 0.34 8.2e-11 Cognitive function; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg26338869 chr17:61819248 STRADA 0.6 8.85 0.43 4.74e-17 Prudent dietary pattern; LIHC cis rs67311347 0.955 rs60554147 chr3:40472503 T/C cg13409248 chr3:40428643 ENTPD3 0.41 6.9 0.35 2.58e-11 Renal cell carcinoma; LIHC cis rs7772486 0.790 rs6926657 chr6:146255794 G/A cg13319975 chr6:146136371 FBXO30 0.36 5.91 0.3 8.12e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2576037 0.526 rs2156050 chr18:44455873 A/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.99e-10 Personality dimensions; LIHC cis rs62458065 0.513 rs702831 chr7:32579715 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -7.13 -0.36 5.88e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs7551222 0.752 rs4951389 chr1:204475834 G/T cg20240347 chr1:204465584 NA -0.34 -7.23 -0.36 3.15e-12 Schizophrenia; LIHC cis rs8067545 0.750 rs28603224 chr17:19985052 G/A cg13482628 chr17:19912719 NA 0.48 7.96 0.4 2.51e-14 Schizophrenia; LIHC cis rs1691799 0.899 rs1060724 chr12:66740444 T/C cg16791601 chr12:66731901 HELB -0.57 -13.99 -0.6 1.79e-35 White blood cell count (basophil); LIHC trans rs11148252 0.553 rs7999849 chr13:53249414 A/G cg18335740 chr13:41363409 SLC25A15 0.56 10.3 0.49 7.81e-22 Lewy body disease; LIHC cis rs208520 0.526 rs9294682 chr6:66795159 G/A cg07460842 chr6:66804631 NA -1.04 -20.11 -0.74 6.25e-60 Exhaled nitric oxide output; LIHC cis rs727505 1.000 rs67552763 chr7:124517857 A/G cg23710748 chr7:124431027 NA -0.32 -5.78 -0.3 1.66e-8 Lewy body disease; LIHC cis rs2404602 0.684 rs157759 chr15:76846990 T/A cg03037974 chr15:76606532 NA 0.63 10.8 0.5 1.39e-23 Blood metabolite levels; LIHC cis rs9522267 0.535 rs9515451 chr13:112234382 A/G cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs11711311 1.000 rs13061150 chr3:113506734 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.12 0.4 8.51e-15 IgG glycosylation; LIHC cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg11644478 chr21:40555479 PSMG1 0.83 10.86 0.51 8.58e-24 Cognitive function; LIHC cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg05697976 chr12:29376483 FAR2 0.31 6.3 0.32 9.14e-10 QT interval; LIHC cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg21724239 chr8:58056113 NA 0.61 7.14 0.36 5.75e-12 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg08645402 chr16:4508243 NA 0.44 8.34 0.41 1.82e-15 Schizophrenia; LIHC cis rs9420 0.961 rs11601320 chr11:57642617 T/C cg19752551 chr11:57585705 CTNND1 -0.47 -6.49 -0.33 2.97e-10 Schizophrenia; LIHC cis rs12980942 0.872 rs2053086 chr19:41799475 C/T cg25627403 chr19:41769009 HNRNPUL1 -0.55 -6.8 -0.35 4.66e-11 Coronary artery disease; LIHC cis rs7762018 0.607 rs75438963 chr6:170047695 G/A cg19338460 chr6:170058176 WDR27 -0.9 -9.03 -0.44 1.28e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs875971 1.000 rs1968225 chr7:65874773 T/C cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC trans rs3780486 0.846 rs7849148 chr9:33138352 A/T cg04842962 chr6:43655489 MRPS18A 1.08 25.4 0.81 1.05e-80 IgG glycosylation; LIHC cis rs2228479 0.850 rs11076619 chr16:89831243 C/A cg04013166 chr16:89971882 TCF25 0.52 6.46 0.33 3.55e-10 Skin colour saturation; LIHC cis rs782590 0.967 rs1975487 chr2:55809054 A/G cg18811423 chr2:55921094 PNPT1 0.9 14.17 0.61 3.42e-36 Metabolic syndrome; LIHC cis rs61677309 0.964 rs60652614 chr11:118168543 G/T cg06090739 chr11:118230722 UBE4A 0.34 6.29 0.32 9.96e-10 Lung cancer in ever smokers; LIHC cis rs921968 0.613 rs2303565 chr2:219545309 T/C cg02985541 chr2:219472218 PLCD4 -0.39 -6.52 -0.33 2.58e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs4650994 0.593 rs28445692 chr1:178511892 G/C cg05350800 chr1:178550844 NA -0.33 -7.11 -0.36 6.87e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7613875 0.620 rs7624030 chr3:50071279 A/C cg05623727 chr3:50126028 RBM5 -0.34 -5.89 -0.3 9.44e-9 Body mass index; LIHC trans rs2727020 0.688 rs4929894 chr11:49196333 G/C cg03929089 chr4:120376271 NA -0.78 -13.53 -0.59 1.05e-33 Coronary artery disease; LIHC cis rs7739232 0.920 rs7748828 chr6:53517643 A/C cg13840445 chr6:53530628 KLHL31 -0.86 -5.74 -0.3 2.11e-8 Hip circumference adjusted for BMI; LIHC cis rs875971 1.000 rs937495 chr7:65779798 A/G cg18876405 chr7:65276391 NA -0.36 -6.58 -0.34 1.74e-10 Aortic root size; LIHC cis rs6502050 0.835 rs12051747 chr17:80114814 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.89 -0.3 9.22e-9 Life satisfaction; LIHC cis rs9733 0.596 rs2065900 chr1:150652202 A/G cg13175981 chr1:150552382 MCL1 -0.44 -6.16 -0.32 2.07e-9 Tonsillectomy; LIHC cis rs60871478 0.786 rs62432898 chr7:826102 G/A cg27478167 chr7:817139 HEATR2 -0.51 -6.82 -0.35 4.1e-11 Cerebrospinal P-tau181p levels; LIHC cis rs11190604 1.000 rs11190569 chr10:102227409 C/T cg07080220 chr10:102295463 HIF1AN 0.51 7.51 0.38 5.26e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs16828019 0.852 rs3904243 chr1:41574852 T/G cg03962019 chr1:41807865 NA 0.5 7.22 0.36 3.33e-12 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.550 rs1438307 chr2:136499166 A/C cg25344623 chr2:136566232 LCT -0.43 -8.85 -0.43 4.86e-17 Mosquito bite size; LIHC cis rs9611565 0.592 rs5996037 chr22:41965292 A/G cg03806693 chr22:41940476 POLR3H -0.87 -9.75 -0.47 5.67e-20 Vitiligo; LIHC cis rs597539 0.652 rs513615 chr11:68705504 G/T cg06028808 chr11:68637592 NA 0.45 5.75 0.3 2.02e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs4927850 1.000 rs4927850 chr3:195751630 C/T cg16724585 chr3:197361211 NA 0.44 6.25 0.32 1.2e-9 Pancreatic cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg07085156 chr10:64959524 JMJD1C -0.28 -6.37 -0.33 6.12e-10 Calcium levels; LIHC cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg08280861 chr8:58055591 NA 0.52 5.87 0.3 1.01e-8 Developmental language disorder (linguistic errors); LIHC trans rs875971 0.545 rs67688847 chr7:65626051 G/A cg26939375 chr7:64535504 NA 0.41 6.47 0.33 3.36e-10 Aortic root size; LIHC cis rs4332037 0.826 rs4721188 chr7:1953615 G/A cg23422044 chr7:1970798 MAD1L1 0.54 6.49 0.33 3.01e-10 Bipolar disorder; LIHC cis rs7528419 1.000 rs629301 chr1:109818306 G/T cg20569855 chr1:109824440 PSRC1 0.49 6.55 0.33 2.12e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs611744 0.870 rs613261 chr8:109165949 A/G cg18478394 chr8:109455254 TTC35 0.39 6.66 0.34 1.1e-10 Dupuytren's disease; LIHC cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.9 -10.39 -0.49 3.83e-22 Platelet count; LIHC cis rs7100689 0.753 rs1856773 chr10:82060484 T/A cg01528321 chr10:82214614 TSPAN14 0.87 11.96 0.54 8.55e-28 Post bronchodilator FEV1; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg09521871 chr19:3752665 APBA3 -0.38 -6.12 -0.31 2.53e-9 Calcium levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17979863 chr2:231852034 NA 0.41 6.49 0.33 3.06e-10 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14022721 chr22:25507536 KIAA1671 0.46 6.93 0.35 2.1e-11 Pancreatic cancer; LIHC cis rs41271473 0.526 rs12353961 chr1:228738252 G/C cg10167378 chr1:228756711 NA 0.65 6.53 0.33 2.35e-10 Chronic lymphocytic leukemia; LIHC cis rs7208859 0.673 rs11656845 chr17:29206164 G/T cg13385521 chr17:29058706 SUZ12P 0.82 7.91 0.39 3.63e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs66887589 0.616 rs11731675 chr4:120212514 T/C cg25214090 chr10:38739885 LOC399744 0.44 6.99 0.35 1.42e-11 Diastolic blood pressure; LIHC cis rs12477438 0.798 rs972768 chr2:99682397 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.53 -0.49 1.24e-22 Chronic sinus infection; LIHC trans rs561341 1.000 rs550923 chr17:30327013 G/C cg20587970 chr11:113659929 NA -1.39 -11.8 -0.54 3.55e-27 Hip circumference adjusted for BMI; LIHC cis rs2412488 0.893 rs7686876 chr4:54281075 C/T cg22241045 chr4:54363911 LNX1 -0.41 -6.71 -0.34 8.15e-11 DNA methylation (variation); LIHC cis rs2976388 0.609 rs2585148 chr8:143796193 C/G cg06565975 chr8:143823917 SLURP1 0.33 6.19 0.32 1.69e-9 Urinary tract infection frequency; LIHC cis rs12711979 0.509 rs10178286 chr2:3823821 A/G cg17052675 chr2:3827356 NA 0.7 14.78 0.62 1.42e-38 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs514406 0.825 rs487453 chr1:53271225 T/C cg16325326 chr1:53192061 ZYG11B -0.42 -7.14 -0.36 5.79e-12 Monocyte count; LIHC cis rs2404602 0.647 rs11072618 chr15:77019342 A/G cg23625390 chr15:77176239 SCAPER -0.55 -9.11 -0.44 6.82e-18 Blood metabolite levels; LIHC cis rs12365397 0.569 rs1353465 chr11:43242587 A/G cg16667275 chr11:43333495 API5 -0.38 -5.76 -0.3 1.87e-8 Migraine; LIHC cis rs7909074 1.000 rs10751361 chr10:45398186 C/A cg05187965 chr10:45406764 TMEM72 -0.27 -6.69 -0.34 9.31e-11 Mean corpuscular volume; LIHC trans rs10242455 0.702 rs59240302 chr7:99072991 C/G cg09045935 chr12:6379348 NA 0.84 6.92 0.35 2.28e-11 Blood metabolite levels; LIHC cis rs7739232 0.920 rs7748828 chr6:53517643 A/C cg26980034 chr6:53530624 KLHL31 -0.86 -5.78 -0.3 1.66e-8 Hip circumference adjusted for BMI; LIHC cis rs6960043 0.818 rs10258074 chr7:15064216 A/T cg19272540 chr7:15055459 NA -0.24 -6.53 -0.33 2.41e-10 Type 2 diabetes; LIHC cis rs7071206 0.891 rs10824559 chr10:79409222 A/G cg07817648 chr10:79422355 NA -0.34 -7.2 -0.36 3.84e-12 Bone mineral density; LIHC cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg00825309 chr19:58991885 ZNF446 -0.52 -8.29 -0.41 2.66e-15 Uric acid clearance; LIHC cis rs7095944 0.614 rs10901817 chr10:126443404 A/T cg08799069 chr10:126477246 METTL10 -0.37 -6.48 -0.33 3.29e-10 Asthma; LIHC cis rs9611519 0.894 rs9611486 chr22:41458784 C/G cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.13e-14 Neuroticism; LIHC cis rs6089829 0.962 rs7267951 chr20:61665979 A/G cg08564027 chr20:61660810 NA 0.4 7.6 0.38 2.91e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Bipolar disorder; LIHC cis rs2050392 0.767 rs1536833 chr10:30699265 C/T cg25182066 chr10:30743637 MAP3K8 0.58 9.06 0.44 1.02e-17 Inflammatory bowel disease; LIHC cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg27297192 chr10:134578999 INPP5A 0.52 7.02 0.35 1.21e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04460041 chr16:2293178 DCI 0.43 6.17 0.32 1.89e-9 Longevity; LIHC cis rs2991971 0.810 rs12738318 chr1:45929589 A/G cg24296786 chr1:45957014 TESK2 -0.57 -8.68 -0.42 1.61e-16 High light scatter reticulocyte count; LIHC cis rs7502590 0.920 rs56084168 chr17:79084574 C/T cg02064366 chr17:79045526 BAIAP2 0.54 6.49 0.33 3.1e-10 Neuroticism; LIHC cis rs4820294 0.770 rs7285699 chr22:38066556 A/C cg26138144 chr22:38071188 LGALS1 0.42 7.76 0.39 9.63e-14 Fat distribution (HIV); LIHC cis rs8016982 0.632 rs7142641 chr14:81677454 A/G cg01989461 chr14:81687754 GTF2A1 0.53 9.24 0.45 2.77e-18 Schizophrenia; LIHC cis rs240764 0.610 rs41288423 chr6:101166095 G/A cg09795085 chr6:101329169 ASCC3 -0.47 -6.74 -0.34 6.59e-11 Neuroticism; LIHC cis rs1355223 0.902 rs7129089 chr11:34699699 T/C cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.11 -0.31 2.7e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs875971 0.545 rs12673308 chr7:65631361 C/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.5 0.38 5.5e-13 Aortic root size; LIHC cis rs4689592 0.503 rs11937667 chr4:7057037 C/G cg26116260 chr4:7069785 GRPEL1 -1.0 -17.38 -0.68 6.17e-49 Monocyte percentage of white cells; LIHC cis rs6061231 1.000 rs6061231 chr20:60956917 C/A cg24112000 chr20:60950667 NA -0.62 -9.36 -0.45 1.1e-18 Colorectal cancer; LIHC cis rs7095607 0.606 rs6480313 chr10:69957928 C/T cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.64e-9 Lung function (FVC); LIHC cis rs3015497 0.616 rs6572678 chr14:51090115 T/G cg09863266 chr14:51125203 SAV1 -0.39 -6.18 -0.32 1.85e-9 Mean platelet volume; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18769103 chr1:236445447 ERO1LB -0.5 -6.59 -0.34 1.66e-10 Systolic blood pressure; LIHC cis rs7914558 1.000 rs10883837 chr10:104896486 G/A cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4684776 0.935 rs4684067 chr3:11408873 G/C cg00170343 chr3:11313890 ATG7 -0.45 -6.2 -0.32 1.64e-9 Small vessel stroke; LIHC trans rs800082 0.768 rs2222702 chr3:144258814 T/A cg24215973 chr2:240111563 HDAC4 0.44 6.26 0.32 1.15e-9 Smoking behavior; LIHC cis rs240764 0.658 rs12212435 chr6:101196080 T/C cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.34e-9 Neuroticism; LIHC trans rs7618501 0.633 rs2353579 chr3:50027774 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.56 9.18 0.44 4.06e-18 Intelligence (multi-trait analysis); LIHC cis rs7312933 0.737 rs10880261 chr12:42573822 T/C cg17420585 chr12:42539391 GXYLT1 -0.37 -5.91 -0.3 8.23e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs2504916 0.830 rs2504934 chr6:160781666 A/G cg27253887 chr6:149867208 PPIL4 -0.54 -6.08 -0.31 3.29e-9 Response to hepatitis C treatment; LIHC cis rs892961 0.720 rs103458 chr17:75416031 A/G cg05865280 chr17:75406074 SEPT9 0.62 11.49 0.53 4.61e-26 Airflow obstruction; LIHC cis rs16858210 0.607 rs953419 chr3:183585883 C/T cg25686905 chr3:183603175 PARL 0.45 8.11 0.4 9.4e-15 Menopause (age at onset); LIHC trans rs7916441 1.000 rs1815314 chr10:80928793 C/T cg19914578 chr14:75530481 ACYP1 -0.48 -6.25 -0.32 1.19e-9 Height;Sitting height ratio; LIHC cis rs4319547 0.698 rs4039670 chr12:122822655 A/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.24 -0.36 3.03e-12 Body mass index; LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC trans rs35110281 0.714 rs7277539 chr21:45053011 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.11 0.31 2.73e-9 Mean corpuscular volume; LIHC cis rs6723226 0.572 rs176404 chr2:32638846 T/C cg02381751 chr2:32503542 YIPF4 -0.58 -8.34 -0.41 1.79e-15 Intelligence (multi-trait analysis); LIHC cis rs6547741 1.000 rs6718128 chr2:27833752 A/G cg27432699 chr2:27873401 GPN1 -0.72 -11.73 -0.54 6.04e-27 Oral cavity cancer; LIHC cis rs10106298 1.000 rs4734654 chr8:103669991 A/G cg10187029 chr8:103597600 NA 0.53 6.93 0.35 2.13e-11 Schizophrenia; LIHC cis rs2204008 0.687 rs11181339 chr12:38322271 G/T cg26384229 chr12:38710491 ALG10B 0.57 7.97 0.4 2.43e-14 Bladder cancer; LIHC cis rs11122272 0.735 rs2250749 chr1:231485763 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.2 -0.52 5.02e-25 Hemoglobin concentration; LIHC cis rs7520050 0.931 rs6686134 chr1:46378268 A/G cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.97e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7945718 0.839 rs763373 chr11:12840342 C/G cg25843174 chr11:12811716 TEAD1 -0.35 -8.2 -0.41 4.96e-15 Educational attainment (years of education); LIHC cis rs7520050 0.807 rs4468203 chr1:46113272 T/C cg24296786 chr1:45957014 TESK2 -0.39 -5.88 -0.3 9.53e-9 Red blood cell count;Reticulocyte count; LIHC cis rs116095464 0.558 rs7708515 chr5:234989 C/G cg22496380 chr5:211416 CCDC127 -1.01 -10.79 -0.5 1.49e-23 Breast cancer; LIHC cis rs17739167 0.550 rs2665213 chr15:42234265 T/G cg20935245 chr15:42234343 EHD4 -0.42 -7.82 -0.39 6.41e-14 Monocyte count; LIHC cis rs4631830 0.720 rs2125770 chr10:51514824 T/C cg16070123 chr10:51489643 NA -0.38 -5.94 -0.31 7.02e-9 Prostate-specific antigen levels; LIHC cis rs6695567 0.869 rs1679941 chr1:53614976 A/G cg20326410 chr1:53600821 SLC1A7 0.27 5.86 0.3 1.1e-8 Systemic lupus erythematosus; LIHC cis rs10876993 0.928 rs1689586 chr12:58079586 A/T cg18357645 chr12:58087776 OS9 0.53 8.7 0.43 1.41e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs727563 0.594 rs5758408 chr22:42077737 A/C cg03806693 chr22:41940476 POLR3H 0.98 10.55 0.5 1e-22 Crohn's disease;Inflammatory bowel disease; LIHC cis rs11958404 0.932 rs72816600 chr5:157436349 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs3106136 0.678 rs11944992 chr4:95298176 G/A cg11021082 chr4:95130006 SMARCAD1 0.36 6.13 0.31 2.4e-9 Capecitabine sensitivity; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01145284 chr2:10580628 ODC1 0.4 6.26 0.32 1.16e-9 Longevity; LIHC cis rs7258465 1.000 rs2303695 chr19:18562624 C/T cg10790698 chr19:18539756 SSBP4 -0.37 -7.68 -0.38 1.66e-13 Breast cancer; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg24196351 chr3:149182962 NA 0.42 6.05 0.31 3.74e-9 Bilirubin levels; LIHC cis rs7223966 0.655 rs9906924 chr17:61634538 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 5.9 0.3 8.81e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2274273 1.000 rs6573006 chr14:55610432 T/C cg01864836 chr14:55583639 NA -0.37 -6.72 -0.34 7.44e-11 Protein biomarker; LIHC cis rs3820068 0.581 rs16851819 chr1:15918739 C/T cg17385448 chr1:15911702 AGMAT -0.33 -5.83 -0.3 1.25e-8 Systolic blood pressure; LIHC cis rs708547 0.836 rs1625691 chr4:57845740 T/C cg16868167 chr4:57843880 C4orf14;POLR2B 0.66 9.55 0.46 2.64e-19 Response to bleomycin (chromatid breaks); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03373091 chr22:38902403 DDX17 -0.44 -6.78 -0.34 5.33e-11 Pancreatic cancer; LIHC cis rs57221529 0.545 rs55955015 chr5:575182 A/G cg09021430 chr5:549028 NA -0.45 -9.07 -0.44 9.18e-18 Lung disease severity in cystic fibrosis; LIHC cis rs6964587 0.839 rs62466809 chr7:91472801 A/G cg17063962 chr7:91808500 NA 0.97 18.14 0.7 5.46e-52 Breast cancer; LIHC cis rs6450176 1.000 rs3776715 chr5:53299095 T/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.13 -0.44 6.31e-18 Bipolar disorder; LIHC cis rs10751667 0.643 rs7479473 chr11:929111 C/T cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs7044106 0.762 rs10984972 chr9:123409864 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.12 0.52 1.03e-24 Hip circumference adjusted for BMI; LIHC cis rs763121 0.853 rs1065201 chr22:39069510 T/C cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs6120849 0.754 rs3746436 chr20:33586193 C/T cg24642439 chr20:33292090 TP53INP2 0.65 7.15 0.36 5.41e-12 Protein C levels; LIHC trans rs9641123 0.609 rs982457 chr7:93209963 C/T cg09745688 chr16:2908918 PRSS22 -0.36 -6.21 -0.32 1.57e-9 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs8060686 0.641 rs59708959 chr16:68123916 A/T cg09835421 chr16:68378352 PRMT7 -0.5 -5.82 -0.3 1.32e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs2404602 0.716 rs12441247 chr15:76812316 T/C cg03037974 chr15:76606532 NA 0.78 15.75 0.65 2.13e-42 Blood metabolite levels; LIHC cis rs9486719 1.000 rs4262195 chr6:96929475 T/C cg06623918 chr6:96969491 KIAA0776 -0.66 -6.7 -0.34 8.45e-11 Migraine;Coronary artery disease; LIHC cis rs1256061 0.669 rs1256065 chr14:64698932 G/T cg23250157 chr14:64679961 SYNE2 0.4 5.83 0.3 1.29e-8 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg02993280 chr1:107599747 PRMT6 -0.71 -11.61 -0.53 1.65e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4466137 0.909 rs4466136 chr5:82985576 T/G cg16102102 chr5:83017553 HAPLN1 -0.58 -8.77 -0.43 8.49e-17 Prostate cancer; LIHC cis rs8141529 0.732 rs3788409 chr22:29198151 T/G cg15103426 chr22:29168792 CCDC117 0.67 11.68 0.53 9.38e-27 Lymphocyte counts; LIHC cis rs6545883 1.000 rs6742276 chr2:61768745 G/A cg15711740 chr2:61764176 XPO1 -0.43 -6.11 -0.31 2.68e-9 Tuberculosis; LIHC trans rs208520 0.661 rs207079 chr6:66770462 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.79 -9.11 -0.44 6.91e-18 Exhaled nitric oxide output; LIHC cis rs17685 0.753 rs10262501 chr7:75668172 G/A cg16684958 chr7:75615977 POR -0.51 -8.5 -0.42 6.02e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17685 0.753 rs10233282 chr7:75790081 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.33 -0.32 7.84e-10 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1814175 0.500 rs1825677 chr11:49233099 T/G cg03929089 chr4:120376271 NA -0.52 -8.17 -0.4 6.09e-15 Height; LIHC cis rs8062405 0.755 rs4787455 chr16:28589455 G/A cg16576597 chr16:28551801 NUPR1 0.49 7.54 0.38 4.29e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8084351 0.599 rs2000696 chr18:50706382 G/A cg24270629 chr18:50823537 DCC -0.43 -6.24 -0.32 1.26e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs208520 0.526 rs6913344 chr6:66754285 A/C cg07460842 chr6:66804631 NA -0.82 -14.76 -0.62 1.74e-38 Exhaled nitric oxide output; LIHC cis rs7937682 0.961 rs1784784 chr11:111483185 C/T cg09085632 chr11:111637200 PPP2R1B -0.88 -10.97 -0.51 3.48e-24 Primary sclerosing cholangitis; LIHC cis rs6960043 0.905 rs7786873 chr7:15060410 A/G cg19272540 chr7:15055459 NA -0.22 -5.99 -0.31 5.23e-9 Type 2 diabetes; LIHC cis rs9733 0.635 rs486836 chr1:150875967 A/T cg17724175 chr1:150552817 MCL1 -0.33 -6.15 -0.32 2.15e-9 Tonsillectomy; LIHC cis rs769267 0.965 rs2074303 chr19:19381755 C/T cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs1707322 0.752 rs7541962 chr1:46235117 G/A cg06784218 chr1:46089804 CCDC17 0.4 7.03 0.36 1.15e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1499614 1.000 rs2141924 chr7:66186246 C/T cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs9640161 0.702 rs11765692 chr7:150026567 C/T cg10018233 chr7:150070692 REPIN1 0.56 9.49 0.46 4.04e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs2075371 0.863 rs1646638 chr7:134008706 T/C cg20476274 chr7:133979776 SLC35B4 0.68 11.24 0.52 3.84e-25 Mean platelet volume; LIHC cis rs2070433 0.799 rs7279002 chr21:47910523 C/T cg12379764 chr21:47803548 PCNT -0.6 -8.9 -0.43 3.29e-17 Lymphocyte counts; LIHC cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg07424592 chr7:64974309 NA -0.8 -9.26 -0.45 2.3e-18 Diabetic kidney disease; LIHC cis rs9905704 0.647 rs11652713 chr17:57079742 C/T cg05425664 chr17:57184151 TRIM37 -0.4 -5.79 -0.3 1.59e-8 Testicular germ cell tumor; LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg21448741 chr8:58168803 NA 0.33 6.0 0.31 4.9e-9 Developmental language disorder (linguistic errors); LIHC cis rs2832191 0.740 rs13048618 chr21:30458684 A/G cg24692254 chr21:30365293 RNF160 0.87 15.84 0.65 8.87e-43 Dental caries; LIHC cis rs3761218 0.668 rs6052079 chr20:3774209 G/T cg25011176 chr20:3776985 CDC25B -0.44 -6.22 -0.32 1.42e-9 Bipolar disorder; LIHC cis rs9303401 0.659 rs17822735 chr17:56620167 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.12 0.55 2.35e-28 Cognitive test performance; LIHC cis rs7086627 0.515 rs4933390 chr10:82213081 A/C cg01528321 chr10:82214614 TSPAN14 0.55 7.69 0.38 1.55e-13 Post bronchodilator FEV1; LIHC cis rs12477438 0.501 rs12995473 chr2:99764884 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.21 21.25 0.75 1.75e-64 Chronic sinus infection; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg04234412 chr22:24373322 LOC391322 -0.73 -10.92 -0.51 5.09e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs709400 0.663 rs3783402 chr14:103967929 C/G cg26031613 chr14:104095156 KLC1 0.7 9.0 0.44 1.62e-17 Body mass index; LIHC cis rs11122272 0.735 rs2486736 chr1:231521478 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.7 11.27 0.52 3e-25 Hemoglobin concentration; LIHC cis rs6684514 1.000 rs2277871 chr1:156246742 A/G cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9814567 1.000 rs9985356 chr3:134232920 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.65 12.14 0.55 1.89e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs778371 0.723 rs35491427 chr2:233688542 C/T cg08000102 chr2:233561755 GIGYF2 -0.76 -9.25 -0.45 2.45e-18 Schizophrenia; LIHC cis rs798554 0.757 rs2533879 chr7:2859847 G/A cg19524238 chr7:2802976 GNA12 -0.4 -5.89 -0.3 9.15e-9 Height; LIHC cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs9393777 0.588 rs6456728 chr6:26477779 G/A cg12826209 chr6:26865740 GUSBL1 0.68 8.09 0.4 1.05e-14 Intelligence (multi-trait analysis); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg20197516 chr17:80373348 C17orf101 0.37 6.32 0.32 8.31e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7592578 0.771 rs4258824 chr2:191395027 C/T cg10560079 chr2:191398806 TMEM194B -0.82 -11.88 -0.54 1.71e-27 Diastolic blood pressure; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg02018802 chr2:220362948 GMPPA 0.46 6.53 0.33 2.42e-10 Alopecia areata; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg14159672 chr1:205819179 PM20D1 0.76 10.84 0.51 9.55e-24 Menarche (age at onset); LIHC cis rs763121 0.889 rs2267390 chr22:38889657 C/T cg06022373 chr22:39101656 GTPBP1 0.63 10.67 0.5 3.98e-23 Menopause (age at onset); LIHC cis rs1371867 0.846 rs1660347 chr8:101314980 G/A cg06636551 chr8:101224915 SPAG1 -0.49 -8.91 -0.43 3e-17 Atrioventricular conduction; LIHC cis rs7615952 0.599 rs7652883 chr3:125707977 T/G cg05084668 chr3:125655381 ALG1L -0.42 -6.93 -0.35 2.11e-11 Blood pressure (smoking interaction); LIHC cis rs1023500 1.000 rs6002552 chr22:42338351 G/A cg04733989 chr22:42467013 NAGA -0.5 -5.93 -0.31 7.53e-9 Schizophrenia; LIHC cis rs12497850 0.931 rs9867373 chr3:48960938 A/T cg06212747 chr3:49208901 KLHDC8B 0.56 7.22 0.36 3.44e-12 Parkinson's disease; LIHC cis rs933688 1.000 rs1035477 chr5:90743325 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.35 0.72 6.94e-57 Smoking behavior; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11878675 chr2:74211845 NA -0.44 -6.48 -0.33 3.12e-10 Cognitive function; LIHC cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg03396347 chr1:1875803 NA -0.49 -9.3 -0.45 1.75e-18 Body mass index; LIHC cis rs3770081 1.000 rs3770081 chr2:86280925 G/T cg01119172 chr2:86362222 SNORD94;PTCD3 0.46 6.34 0.32 7.3e-10 Facial emotion recognition (sad faces); LIHC cis rs2842992 0.724 rs9365097 chr6:160211259 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.61 0.56 3.36e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs2404602 0.716 rs12907805 chr15:76690606 C/T cg03037974 chr15:76606532 NA 0.8 16.63 0.67 6.35e-46 Blood metabolite levels; LIHC cis rs611744 0.905 rs640950 chr8:109157819 T/A cg18478394 chr8:109455254 TTC35 0.35 5.87 0.3 1.05e-8 Dupuytren's disease; LIHC cis rs17253792 0.822 rs17253730 chr14:56157911 A/G cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC cis rs79057730 0.599 rs112891948 chr7:816059 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.79 8.9 0.43 3.3e-17 Initial pursuit acceleration; LIHC cis rs4450131 1.000 rs4450131 chr10:126383363 C/T cg20435097 chr10:126320824 FAM53B 0.49 8.97 0.44 2.05e-17 White blood cell count (basophil); LIHC cis rs10751667 0.666 rs10902255 chr11:967268 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs78456975 0.941 rs6755875 chr2:1557109 T/C cg01028140 chr2:1542097 TPO -0.53 -6.3 -0.32 8.92e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs17685 0.753 rs2868203 chr7:75680026 G/A cg04610667 chr7:75704037 NA 0.35 6.25 0.32 1.23e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs9549328 0.837 rs4907572 chr13:113647321 G/A cg00071026 chr13:113650936 MCF2L -0.37 -5.73 -0.3 2.2e-8 Systolic blood pressure; LIHC cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg20302342 chr1:156215951 PAQR6 -0.3 -5.87 -0.3 1.04e-8 Tonsillectomy; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04324509 chr3:101295624 PCNP 0.4 6.35 0.32 6.77e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14205524 chr15:42787946 SNAP23 -0.46 -7.31 -0.37 1.88e-12 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1008375 0.646 rs4235387 chr4:17569327 T/G cg02297831 chr4:17616191 MED28 0.44 6.24 0.32 1.26e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11190604 0.767 rs10883490 chr10:102194775 C/T cg07080220 chr10:102295463 HIF1AN 0.49 7.0 0.35 1.34e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs7615952 0.932 rs7630077 chr3:125649676 T/C cg07211511 chr3:129823064 LOC729375 -0.85 -10.68 -0.5 3.62e-23 Blood pressure (smoking interaction); LIHC cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg07061783 chr6:25882402 NA -0.42 -6.06 -0.31 3.62e-9 Blood metabolite levels; LIHC cis rs9640161 0.750 rs11769348 chr7:150026753 C/T cg17279839 chr7:150038598 RARRES2 -0.58 -11.8 -0.54 3.54e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs2412488 0.853 rs6838260 chr4:54355824 C/T cg22241045 chr4:54363911 LNX1 -0.4 -6.54 -0.33 2.22e-10 DNA methylation (variation); LIHC cis rs4742903 0.967 rs10820600 chr9:106856692 T/C cg14250997 chr9:106856677 SMC2 0.43 7.37 0.37 1.32e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1059312 0.932 rs11059916 chr12:129287609 C/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -14.35 -0.61 6.85e-37 Systemic lupus erythematosus; LIHC cis rs4076764 1.000 rs7540279 chr1:163429970 A/T cg24596788 chr1:163392923 NA -0.23 -7.16 -0.36 4.92e-12 Motion sickness; LIHC cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg13271783 chr10:134563150 INPP5A -0.59 -7.13 -0.36 5.92e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg26338869 chr17:61819248 STRADA 0.53 7.21 0.36 3.73e-12 Height; LIHC cis rs10423674 0.526 rs12462498 chr19:18832950 A/G cg16673477 chr19:18812017 CRTC1 0.43 7.19 0.36 3.99e-12 Menarche (age at onset); LIHC cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg16262614 chr3:133464971 TF 0.28 6.29 0.32 9.91e-10 Iron status biomarkers; LIHC cis rs6088580 0.524 rs2889855 chr20:33276853 A/G cg07148914 chr20:33460835 GGT7 -0.47 -6.58 -0.34 1.81e-10 Glomerular filtration rate (creatinine); LIHC cis rs13631 0.965 rs7853589 chr9:140003844 A/G cg14289826 chr9:140003911 NA -0.48 -8.3 -0.41 2.51e-15 Cerebrospinal fluid biomarker levels; LIHC cis rs875971 0.638 rs6460305 chr7:66060408 G/A cg18876405 chr7:65276391 NA -0.44 -7.75 -0.39 1.04e-13 Aortic root size; LIHC cis rs9911578 1.000 rs1057068 chr17:56598439 T/C cg05425664 chr17:57184151 TRIM37 0.57 8.48 0.42 7.1e-16 Intelligence (multi-trait analysis); LIHC cis rs6499255 0.951 rs7196943 chr16:69592449 T/A cg15192750 chr16:69999425 NA 0.47 7.05 0.36 9.97e-12 IgE levels; LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs1728785 0.591 rs10775305 chr16:68656460 A/G cg02972257 chr16:68554789 NA -0.51 -5.84 -0.3 1.23e-8 Ulcerative colitis; LIHC cis rs7520050 0.966 rs11810993 chr1:46478793 A/G cg03146154 chr1:46216737 IPP -0.39 -6.37 -0.33 6.12e-10 Red blood cell count;Reticulocyte count; LIHC cis rs3204270 0.639 rs11867543 chr17:79655046 C/T cg18367735 chr17:79674897 NA 0.71 8.28 0.41 2.8e-15 Dental caries; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03044510 chr21:27107978 ATP5J;GABPA -0.44 -6.63 -0.34 1.28e-10 Pancreatic cancer; LIHC trans rs8073060 0.586 rs225265 chr17:33961972 C/T cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2637266 0.745 rs2583039 chr10:78440187 A/G cg18941641 chr10:78392320 NA 0.26 5.76 0.3 1.83e-8 Pulmonary function; LIHC cis rs208520 0.690 rs207108 chr6:66794096 T/C cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC cis rs10464366 0.544 rs953874 chr7:39147916 G/A cg10621924 chr7:39171070 POU6F2 0.4 6.32 0.32 8.26e-10 IgG glycosylation; LIHC cis rs7208859 0.623 rs1061346 chr17:29114229 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6502050 0.835 rs4789675 chr17:80123144 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs12995491 0.902 rs6737641 chr2:88529471 A/T cg24977027 chr2:88469347 THNSL2 -0.34 -5.9 -0.3 8.69e-9 Response to metformin (IC50); LIHC cis rs9309473 0.950 rs7596773 chr2:73846000 C/T cg20560298 chr2:73613845 ALMS1 -0.55 -6.6 -0.34 1.53e-10 Metabolite levels; LIHC cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg03264133 chr6:25882463 NA 0.59 7.87 0.39 4.73e-14 Blood metabolite levels; LIHC cis rs2404602 0.684 rs4886816 chr15:76874707 A/C cg23625390 chr15:77176239 SCAPER -0.55 -9.04 -0.44 1.18e-17 Blood metabolite levels; LIHC cis rs11122272 0.705 rs2491411 chr1:231533448 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.94e-23 Hemoglobin concentration; LIHC cis rs644799 1.000 rs644799 chr11:95564259 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.81 0.67 1.23e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs17685 0.736 rs4732594 chr7:75753273 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7106204 0.513 rs2165784 chr11:24249360 C/A ch.11.24196551F chr11:24239977 NA 0.83 12.0 0.54 6.57e-28 Response to Homoharringtonine (cytotoxicity); LIHC cis rs12477438 0.520 rs13012481 chr2:99754290 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.17 0.81 7.78e-80 Chronic sinus infection; LIHC cis rs35306767 0.715 rs11253539 chr10:1011347 G/A cg26597838 chr10:835615 NA 0.96 9.22 0.45 3.12e-18 Eosinophil percentage of granulocytes; LIHC cis rs796364 0.616 rs6710393 chr2:200697246 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.56 6.03 0.31 4.14e-9 Schizophrenia; LIHC cis rs2576037 0.526 rs2032215 chr18:44439011 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.65 10.16 0.48 2.3e-21 Personality dimensions; LIHC cis rs62458065 1.000 rs79538247 chr7:32467792 A/G cg06627557 chr7:32535165 LSM5;AVL9 -0.64 -7.07 -0.36 8.98e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg00280220 chr17:61926910 NA 0.42 6.87 0.35 2.99e-11 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06128509 chr10:91461539 KIF20B 0.44 6.71 0.34 8.26e-11 Cognitive function; LIHC cis rs882732 0.947 rs3762123 chr14:95029163 A/G cg14866387 chr14:95027382 SERPINA4 -0.44 -6.45 -0.33 3.86e-10 Blood protein levels; LIHC cis rs6570726 0.791 rs952406 chr6:145925616 C/A cg13319975 chr6:146136371 FBXO30 -0.37 -5.89 -0.3 9.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs929354 0.772 rs3802124 chr7:156970609 G/A cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs5769707 0.935 rs9616332 chr22:50047678 C/G cg01652190 chr22:50026171 C22orf34 -0.31 -6.98 -0.35 1.51e-11 Monocyte count;Monocyte percentage of white cells; LIHC trans rs1728785 1.000 rs7192341 chr16:68569224 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.2 0.32 1.62e-9 Ulcerative colitis; LIHC trans rs61931739 0.711 rs7968821 chr12:34318351 G/A cg26384229 chr12:38710491 ALG10B 0.45 6.13 0.31 2.42e-9 Morning vs. evening chronotype; LIHC cis rs11583043 0.874 rs72734253 chr1:101380718 A/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.89 0.3 9.33e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9325144 0.560 rs61929893 chr12:38653366 G/A cg26384229 chr12:38710491 ALG10B -0.59 -8.11 -0.4 8.86e-15 Morning vs. evening chronotype; LIHC cis rs769267 1.000 rs3764567 chr19:19440066 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.62 -9.88 -0.47 2.04e-20 Tonsillectomy; LIHC cis rs1144333 0.655 rs1146649 chr1:76268803 A/G cg22875332 chr1:76189707 ACADM -0.44 -6.76 -0.34 5.87e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs35306767 0.761 rs11253537 chr10:1010735 G/A cg26597838 chr10:835615 NA 0.93 8.86 0.43 4.36e-17 Eosinophil percentage of granulocytes; LIHC cis rs6912958 0.559 rs183599 chr6:88061024 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.61 0.53 1.69e-26 Monocyte percentage of white cells; LIHC cis rs882732 1.000 rs3762122 chr14:95029351 A/T cg14866387 chr14:95027382 SERPINA4 -0.44 -6.46 -0.33 3.59e-10 Blood protein levels; LIHC cis rs1865721 0.728 rs67357037 chr18:73219024 G/T cg26385618 chr18:73139727 C18orf62 -0.27 -6.98 -0.35 1.54e-11 Intelligence; LIHC cis rs9918079 0.542 rs1789 chr4:15664535 G/A cg24225360 chr4:15471699 CC2D2A -0.39 -6.21 -0.32 1.54e-9 Obesity-related traits; LIHC cis rs12611088 0.932 rs1799778 chr19:44059141 G/T cg13740135 chr19:44006432 PHLDB3 0.4 5.72 0.3 2.3e-8 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg23283495 chr1:209979779 IRF6 0.47 7.55 0.38 4.09e-13 Cleft lip with or without cleft palate; LIHC cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4555082 0.834 rs11622165 chr14:105759761 C/A cg06808227 chr14:105710500 BRF1 -0.49 -6.03 -0.31 4.33e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs924607 0.966 rs1709554 chr5:637443 A/G cg04221910 chr5:616842 CEP72 0.41 7.28 0.37 2.28e-12 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs1005277 0.505 rs200937 chr10:38135772 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.86 0.35 3.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs7131987 0.650 rs7957339 chr12:29456495 T/C cg00204748 chr12:29376779 FAR2 0.38 7.03 0.36 1.16e-11 QT interval; LIHC cis rs4474465 0.915 rs10899503 chr11:78149961 C/T cg02023728 chr11:77925099 USP35 0.33 6.0 0.31 4.91e-9 Alzheimer's disease (survival time); LIHC cis rs896854 0.517 rs896851 chr8:95950251 T/C cg13393036 chr8:95962371 TP53INP1 -0.36 -7.31 -0.37 1.95e-12 Type 2 diabetes; LIHC cis rs2153535 0.580 rs9393023 chr6:8469994 T/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC trans rs4718428 0.662 rs34577323 chr7:66310041 G/C cg10756647 chr7:56101905 PSPH 0.63 8.62 0.42 2.51e-16 Corneal structure; LIHC cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg02475777 chr4:1388615 CRIPAK 0.54 8.23 0.41 4e-15 Longevity; LIHC cis rs867186 0.614 rs77221305 chr20:33452040 T/C cg08999081 chr20:33150536 PIGU 0.64 5.8 0.3 1.49e-8 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs1552244 0.882 rs61429272 chr3:10037320 G/C cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.84 -0.54 2.51e-27 Alzheimer's disease; LIHC cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg12311346 chr5:56204834 C5orf35 -0.58 -7.59 -0.38 3.09e-13 Initial pursuit acceleration; LIHC cis rs1055129 0.560 rs3682 chr17:73942150 A/G cg10935138 chr17:73851978 WBP2 0.49 7.26 0.37 2.57e-12 White matter hyperintensity burden; LIHC cis rs35306767 0.623 rs12354710 chr10:1114020 C/T cg20503657 chr10:835505 NA 0.64 5.75 0.3 1.93e-8 Eosinophil percentage of granulocytes; LIHC cis rs4906332 1.000 rs3783400 chr14:103967045 G/A cg04998671 chr14:104000505 TRMT61A -0.43 -5.73 -0.3 2.19e-8 Coronary artery disease; LIHC cis rs12711979 0.509 rs13021385 chr2:3826387 T/C cg17052675 chr2:3827356 NA -0.71 -15.75 -0.65 2.12e-42 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs636291 0.510 rs1307487 chr1:10506667 G/A cg17425144 chr1:10567563 PEX14 0.5 9.62 0.46 1.5e-19 Prostate cancer; LIHC cis rs8180040 0.903 rs2276853 chr3:47282303 G/A cg27129171 chr3:47204927 SETD2 0.68 11.89 0.54 1.6e-27 Colorectal cancer; LIHC cis rs1707322 0.682 rs3014241 chr1:46087879 A/G cg06784218 chr1:46089804 CCDC17 -0.42 -7.52 -0.38 4.8e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8010715 0.816 rs7153156 chr14:24598846 A/G cg23112188 chr14:24563095 PCK2 -0.29 -6.08 -0.31 3.25e-9 IgG glycosylation; LIHC cis rs17666538 0.585 rs1669615 chr8:616665 T/C cg02524346 chr8:600233 NA 0.78 5.94 0.31 6.97e-9 IgG glycosylation; LIHC cis rs4423214 1.000 rs4944956 chr11:71167765 C/T cg24826892 chr11:71159390 DHCR7 0.47 6.12 0.31 2.52e-9 Vitamin D levels; LIHC cis rs7116495 1.000 rs7101701 chr11:71762155 A/G cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs4728302 0.869 rs10231102 chr7:133573310 G/A cg10665199 chr7:133106180 EXOC4 0.35 6.11 0.31 2.77e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs3857067 0.806 rs1876918 chr4:95099424 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.56 -0.38 3.62e-13 QT interval; LIHC cis rs3736485 0.934 rs4143721 chr15:51866781 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs875971 0.895 rs10447522 chr7:65796074 A/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs875971 0.825 rs66981195 chr7:66079035 C/A cg18876405 chr7:65276391 NA -0.34 -6.24 -0.32 1.3e-9 Aortic root size; LIHC cis rs2204008 0.744 rs11514073 chr12:38399553 A/C cg26384229 chr12:38710491 ALG10B 0.8 9.56 0.46 2.48e-19 Bladder cancer; LIHC cis rs2576037 0.526 rs4890699 chr18:44541029 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 11.24 0.52 3.7e-25 Personality dimensions; LIHC cis rs4423214 0.879 rs10898144 chr11:71151540 A/T cg05163923 chr11:71159392 DHCR7 -0.65 -9.23 -0.45 2.99e-18 Vitamin D levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13530817 chr7:72951610 BCL7B -0.41 -6.18 -0.32 1.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs895636 0.848 rs2840037 chr2:45189872 G/A cg16198908 chr2:45192207 NA 0.39 5.94 0.31 6.97e-9 Metabolite levels;Fasting plasma glucose; LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg06873352 chr17:61820015 STRADA 0.73 13.2 0.58 1.95e-32 Prudent dietary pattern; LIHC cis rs67478160 0.609 rs1547604 chr14:104270659 A/T cg08213375 chr14:104286397 PPP1R13B 0.52 9.89 0.47 1.85e-20 Schizophrenia; LIHC trans rs637571 0.510 rs10896052 chr11:65579600 C/A cg17712092 chr4:129076599 LARP1B -0.7 -10.21 -0.48 1.51e-21 Eosinophil percentage of white cells; LIHC cis rs2067615 0.579 rs10861663 chr12:107183589 G/A cg15890332 chr12:107067104 RFX4 0.26 5.94 0.31 6.95e-9 Heart rate; LIHC cis rs1348850 0.914 rs1374437 chr2:178363423 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.49 0.59 1.47e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9399137 0.507 rs11154791 chr6:135379148 A/G cg24558204 chr6:135376177 HBS1L 0.64 10.75 0.5 2.12e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs3770081 1.000 rs56104203 chr2:86336256 C/T cg01119172 chr2:86362222 SNORD94;PTCD3 0.44 6.45 0.33 3.89e-10 Facial emotion recognition (sad faces); LIHC trans rs9858213 1 rs9858213 chr3:49731861 G/T cg21659725 chr3:3221576 CRBN -0.56 -6.19 -0.32 1.69e-9 Educational attainment; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05908079 chr5:64065005 SDCCAG10;SFRS12IP1 -0.5 -6.53 -0.33 2.44e-10 Systolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02010524 chr4:57333365 SRP72 0.46 6.04 0.31 3.95e-9 Pancreatic cancer; LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg11965913 chr1:205819406 PM20D1 0.62 8.97 0.44 2e-17 Menarche (age at onset); LIHC cis rs911119 0.955 rs59059917 chr20:23595675 C/T cg16589663 chr20:23618590 CST3 0.75 7.64 0.38 2.28e-13 Chronic kidney disease; LIHC cis rs6547741 1.000 rs76784350 chr2:27764278 A/G cg27432699 chr2:27873401 GPN1 0.7 11.2 0.52 4.96e-25 Oral cavity cancer; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs7188697 0.922 rs11862156 chr16:58596753 C/T cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs3814231 0.531 rs12771689 chr10:115467068 A/G cg24846397 chr10:115438155 CASP7 -0.43 -7.18 -0.36 4.34e-12 Vitiligo; LIHC cis rs7872515 0.887 rs10820937 chr9:94840206 T/C cg01248375 chr9:94877805 SPTLC1 0.56 8.23 0.41 4.04e-15 Bipolar disorder and schizophrenia; LIHC cis rs8078723 0.738 rs4065321 chr17:38143548 C/T cg17467752 chr17:38218738 THRA -0.59 -10.13 -0.48 2.93e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs3096299 0.933 rs3096297 chr16:89453155 T/G cg00750074 chr16:89608354 SPG7 -0.4 -6.03 -0.31 4.15e-9 Multiple myeloma (IgH translocation); LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg13409248 chr3:40428643 ENTPD3 0.51 8.39 0.41 1.28e-15 Renal cell carcinoma; LIHC trans rs2243480 1.000 rs313831 chr7:65551226 C/T cg10756647 chr7:56101905 PSPH 1.05 12.6 0.56 3.63e-30 Diabetic kidney disease; LIHC cis rs9325144 0.554 rs1906264 chr12:38739490 A/G cg26384229 chr12:38710491 ALG10B 0.59 8.21 0.41 4.57e-15 Morning vs. evening chronotype; LIHC cis rs12744310 1.000 rs57529969 chr1:41771683 G/A cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9420 0.528 rs10896632 chr11:57390302 G/A cg19752551 chr11:57585705 CTNND1 -0.47 -6.12 -0.31 2.59e-9 Schizophrenia; LIHC cis rs2976388 1.000 rs1045531 chr8:143763547 C/A cg06565975 chr8:143823917 SLURP1 -0.31 -5.89 -0.3 9.24e-9 Urinary tract infection frequency; LIHC trans rs75804782 0.641 rs1030786 chr2:239361150 A/G cg01134436 chr17:81009848 B3GNTL1 0.82 6.92 0.35 2.19e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs6466055 0.777 rs10953470 chr7:104871892 G/T cg04380332 chr7:105027541 SRPK2 0.36 6.84 0.35 3.56e-11 Schizophrenia; LIHC cis rs6942756 0.774 rs6946288 chr7:129004277 A/G cg02491457 chr7:128862824 NA -0.54 -8.21 -0.41 4.45e-15 White matter hyperintensity burden; LIHC cis rs10078 0.559 rs2672725 chr5:434981 G/C cg07599136 chr5:415885 AHRR 0.74 11.89 0.54 1.65e-27 Fat distribution (HIV); LIHC cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg27297192 chr10:134578999 INPP5A 0.54 7.52 0.38 5e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1538970 0.962 rs9429076 chr1:45819489 A/G cg05343316 chr1:45956843 TESK2 0.54 7.67 0.38 1.75e-13 Platelet count; LIHC cis rs7224737 1.000 rs8070446 chr17:40285879 G/A cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs7819412 0.635 rs2409716 chr8:11010748 C/T cg00598335 chr8:11627530 NEIL2 -0.4 -5.88 -0.3 9.85e-9 Triglycerides; LIHC cis rs4727027 0.933 rs7788925 chr7:148831621 A/G cg23583168 chr7:148888333 NA -0.73 -10.34 -0.49 5.46e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg05665937 chr4:1216051 CTBP1 0.45 6.32 0.32 8.06e-10 Obesity-related traits; LIHC cis rs546131 0.642 rs568529 chr11:34842506 C/A cg06937548 chr11:34938143 PDHX;APIP 0.55 7.16 0.36 5.1e-12 Lung disease severity in cystic fibrosis; LIHC cis rs1577917 1.000 rs12203924 chr6:86776412 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.04 -0.48 5.98e-21 Response to antipsychotic treatment; LIHC cis rs6502050 0.835 rs8081783 chr17:80117388 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs9649213 0.614 rs9641236 chr7:97998124 T/A cg09267113 chr7:98030324 BAIAP2L1 -0.58 -10.24 -0.48 1.17e-21 Prostate cancer (SNP x SNP interaction); LIHC cis rs72634258 0.836 rs9658012 chr1:7989022 C/T cg00042356 chr1:8021962 PARK7 0.86 8.94 0.44 2.49e-17 Inflammatory bowel disease; LIHC cis rs4820294 0.516 rs12627973 chr22:38096697 A/G cg26138144 chr22:38071188 LGALS1 0.72 10.53 0.49 1.17e-22 Fat distribution (HIV); LIHC cis rs600806 0.714 rs2781552 chr1:110025881 A/G cg08911820 chr1:110026001 ATXN7L2 0.55 6.8 0.35 4.67e-11 Intelligence (multi-trait analysis); LIHC cis rs7833986 0.501 rs2953910 chr8:56968761 C/G cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.02e-16 Height; LIHC cis rs477692 0.789 rs506915 chr10:131398005 A/G cg19680672 chr10:131412579 MGMT -0.44 -6.89 -0.35 2.76e-11 Response to temozolomide; LIHC cis rs1801251 1.000 rs1022330 chr2:233577330 G/A cg25237894 chr2:233734115 C2orf82 0.56 10.94 0.51 4.4e-24 Coronary artery disease; LIHC cis rs909002 0.849 rs2280386 chr1:32086912 A/C cg13919466 chr1:32135498 COL16A1 -0.32 -6.21 -0.32 1.55e-9 Intelligence (multi-trait analysis); LIHC cis rs72720396 1.000 rs72720396 chr1:91191582 A/G cg13456504 chr1:91191583 NA 0.53 7.53 0.38 4.59e-13 Morning vs. evening chronotype;Chronotype; LIHC cis rs35306767 0.903 rs35370435 chr10:898205 T/C cg20503657 chr10:835505 NA 1.33 14.33 0.61 8.06e-37 Eosinophil percentage of granulocytes; LIHC cis rs2108622 0.727 rs12611308 chr19:15978586 C/T cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.87e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs7772486 0.846 rs6908063 chr6:146403618 T/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.88 -0.3 9.71e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg11062466 chr8:58055876 NA -0.49 -7.4 -0.37 1.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.505 rs1737583 chr6:8536812 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.47 0.42 7.58e-16 Motion sickness; LIHC cis rs9640161 0.789 rs3735172 chr7:150028958 C/T cg17279839 chr7:150038598 RARRES2 -0.51 -10.55 -0.5 1.05e-22 Blood protein levels;Circulating chemerin levels; LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 9.04e-33 Prudent dietary pattern; LIHC cis rs3741404 0.609 rs641378 chr11:63869493 T/C cg18225595 chr11:63971243 STIP1 0.45 7.27 0.37 2.4e-12 Platelet count; LIHC cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg06634786 chr22:41940651 POLR3H 0.8 9.02 0.44 1.43e-17 Vitiligo; LIHC cis rs1475718 0.526 rs10785876 chr9:137122767 C/G cg21243944 chr9:137118148 NA -0.45 -6.28 -0.32 1e-9 Immature fraction of reticulocytes;Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs12477438 0.765 rs10193039 chr2:99692373 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.54 -8.8 -0.43 7e-17 Chronic sinus infection; LIHC cis rs7131987 0.903 rs6487796 chr12:29422764 A/G cg00204748 chr12:29376779 FAR2 0.42 7.83 0.39 6.32e-14 QT interval; LIHC cis rs1268083 0.546 rs9398785 chr6:126057748 A/G cg05901451 chr6:126070800 HEY2 -0.62 -12.31 -0.55 4.33e-29 Migraine; LIHC cis rs67478160 0.643 rs1535098 chr14:104216513 T/A cg08213375 chr14:104286397 PPP1R13B 0.65 13.0 0.58 1.15e-31 Schizophrenia; LIHC cis rs2832191 0.967 rs2898160 chr21:30487496 A/G cg08807101 chr21:30365312 RNF160 -0.59 -9.3 -0.45 1.74e-18 Dental caries; LIHC cis rs72772090 0.708 rs17082200 chr5:96048604 T/C cg17330273 chr5:96107758 CAST;ERAP1 -0.47 -5.78 -0.3 1.73e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12611088 0.965 rs3810378 chr19:44081601 C/G cg13740135 chr19:44006432 PHLDB3 -0.39 -5.73 -0.3 2.26e-8 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs778371 0.671 rs13008436 chr2:233719948 C/T cg08000102 chr2:233561755 GIGYF2 -0.8 -9.37 -0.45 9.9e-19 Schizophrenia; LIHC cis rs9611519 0.894 rs13053242 chr22:41459486 G/A cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.13e-14 Neuroticism; LIHC trans rs675026 0.926 rs604844 chr6:154454973 C/T cg11601662 chr7:30066256 FKBP14 -0.49 -6.11 -0.31 2.73e-9 Hypertension; LIHC cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.7 0.34 8.59e-11 Bipolar disorder; LIHC cis rs10905065 1.000 rs10905065 chr10:5769827 C/T cg11519256 chr10:5708881 ASB13 0.45 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs9303401 0.659 rs62081314 chr17:56778328 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.9 11.85 0.54 2.26e-27 Cognitive test performance; LIHC cis rs7160336 0.515 rs7152352 chr14:74611271 A/G cg05179529 chr14:74551516 LIN52;ALDH6A1 -0.4 -5.76 -0.3 1.86e-8 Blood protein levels; LIHC cis rs4713118 0.955 rs9368528 chr6:27683798 G/A cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC cis rs2576037 0.526 rs9962523 chr18:44486414 A/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.5 -7.21 -0.36 3.61e-12 Personality dimensions; LIHC trans rs62103177 0.673 rs7242867 chr18:77603270 A/T cg05926928 chr17:57297772 GDPD1 0.56 7.27 0.37 2.46e-12 Opioid sensitivity; LIHC cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg06640241 chr16:89574553 SPG7 0.66 10.7 0.5 3.11e-23 Multiple myeloma (IgH translocation); LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg02990361 chr1:107599529 PRMT6 -0.66 -10.94 -0.51 4.5e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs116248771 0.739 rs4680456 chr3:158397842 C/T cg16708174 chr3:158430962 RARRES1 0.49 6.53 0.33 2.32e-10 diarrhoeal disease at age 2; LIHC cis rs61712019 0.679 rs1997526 chr2:77713329 G/C cg11252801 chr2:77748917 LRRTM4 0.55 7.57 0.38 3.46e-13 Schizophrenia; LIHC cis rs10751667 0.643 rs10751669 chr11:942344 C/G ch.11.42038R chr11:967971 AP2A2 -0.53 -9.76 -0.47 5.2e-20 Alzheimer's disease (late onset); LIHC cis rs1005277 0.579 rs2505257 chr10:38372664 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.9 -0.3 8.55e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.44e-8 Alzheimer's disease; LIHC cis rs875971 0.789 rs10260426 chr7:65736042 G/T cg11764359 chr7:65958608 NA -0.77 -13.25 -0.58 1.25e-32 Aortic root size; LIHC cis rs4742903 0.904 rs2417487 chr9:106887581 A/G cg14250997 chr9:106856677 SMC2 0.41 7.28 0.37 2.31e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg09222892 chr1:25734099 RHCE -0.47 -8.69 -0.43 1.58e-16 Erythrocyte sedimentation rate; LIHC cis rs798554 0.797 rs798491 chr7:2800521 A/G cg19346786 chr7:2764209 NA -0.46 -7.08 -0.36 8.32e-12 Height; LIHC cis rs9300255 0.596 rs4460848 chr12:123677810 A/G cg05973401 chr12:123451056 ABCB9 0.45 6.21 0.32 1.56e-9 Neutrophil percentage of white cells; LIHC cis rs2073499 1.000 rs57319506 chr3:50285677 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.67 7.01 0.35 1.31e-11 Schizophrenia; LIHC cis rs9814567 0.752 rs4955468 chr3:134340850 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.55 -8.87 -0.43 4.03e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4969178 0.930 rs11077363 chr17:76397309 C/T cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs10504229 0.871 rs60342323 chr8:58154899 T/C cg21724239 chr8:58056113 NA 0.44 6.09 0.31 3.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7659604 0.502 rs11098640 chr4:122675875 G/A cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.7e-11 Type 2 diabetes; LIHC cis rs523522 0.962 rs2393590 chr12:120913900 G/A cg27279351 chr12:120934652 DYNLL1 0.66 11.73 0.54 6.38e-27 High light scatter reticulocyte count; LIHC cis rs6782228 0.565 rs11719239 chr3:128419054 A/G cg16766828 chr3:128327626 NA -0.38 -5.98 -0.31 5.54e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs637571 0.726 rs526631 chr11:65681965 T/G cg04055107 chr11:65626734 MUS81;CFL1 -0.41 -6.06 -0.31 3.65e-9 Eosinophil percentage of white cells; LIHC cis rs758324 0.947 rs1500115 chr5:131216427 G/T cg06307176 chr5:131281290 NA 0.4 5.73 0.3 2.15e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7131987 0.650 rs6487808 chr12:29463359 C/T cg14222432 chr12:29376421 FAR2 -0.34 -6.74 -0.34 6.84e-11 QT interval; LIHC cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg13866156 chr1:1669148 SLC35E2 -0.71 -13.88 -0.6 4.88e-35 Body mass index; LIHC cis rs243505 0.660 rs10274535 chr7:148543525 A/G cg09806900 chr7:148480153 CUL1 0.43 6.07 0.31 3.49e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 0.964 rs6978429 chr7:65959876 T/G cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.64e-11 Aortic root size; LIHC cis rs748404 0.588 rs506120 chr15:43802024 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.51 7.75 0.39 1.04e-13 Lung cancer; LIHC cis rs11148252 0.846 rs7323666 chr13:53006058 T/C cg00495681 chr13:53174319 NA 0.37 6.14 0.32 2.24e-9 Lewy body disease; LIHC cis rs7107174 0.901 rs2450140 chr11:77924388 T/C cg02023728 chr11:77925099 USP35 0.48 8.89 0.43 3.67e-17 Testicular germ cell tumor; LIHC cis rs929354 0.772 rs6459738 chr7:156998532 T/G cg17757837 chr7:157058334 UBE3C 0.74 12.06 0.55 3.84e-28 Body mass index; LIHC cis rs2839186 0.770 rs2839984 chr21:47671690 A/G cg12016809 chr21:47604291 C21orf56 0.49 7.58 0.38 3.24e-13 Testicular germ cell tumor; LIHC cis rs13118159 0.872 rs4974605 chr4:1346389 C/G cg13395646 chr4:1353034 KIAA1530 -0.67 -9.19 -0.44 3.94e-18 Longevity; LIHC cis rs35110281 0.659 rs2236667 chr21:45112939 A/G cg21573476 chr21:45109991 RRP1B -0.59 -11.15 -0.52 7.97e-25 Mean corpuscular volume; LIHC cis rs7793919 0.726 rs4720401 chr7:4780943 G/A cg09789173 chr7:4769017 FOXK1 0.73 10.54 0.5 1.13e-22 Mosquito bite size; LIHC cis rs7927592 0.913 rs10896329 chr11:68250029 A/G cg01657329 chr11:68192670 LRP5 -0.45 -5.86 -0.3 1.09e-8 Total body bone mineral density; LIHC cis rs11168351 0.927 rs10875716 chr12:48389023 C/T cg21466736 chr12:48725269 NA -0.55 -7.35 -0.37 1.43e-12 Bipolar disorder and schizophrenia; LIHC cis rs3736485 0.966 rs11070856 chr15:51853817 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1008375 0.932 rs12500912 chr4:17603318 C/T cg16339924 chr4:17578868 LAP3 0.5 6.72 0.34 7.6e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg27432699 chr2:27873401 GPN1 -0.49 -7.07 -0.36 8.55e-12 Total body bone mineral density; LIHC cis rs34172651 0.876 rs2547033 chr16:24743657 C/T cg00339695 chr16:24857497 SLC5A11 0.32 5.87 0.3 1.03e-8 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs2952156 0.883 rs1495100 chr17:37832279 C/T cg00129232 chr17:37814104 STARD3 -0.55 -10.38 -0.49 4.08e-22 Asthma; LIHC trans rs7178375 0.941 rs35497908 chr15:31224071 C/T cg04373760 chr16:53404718 NA 0.59 7.59 0.38 3.1e-13 Hypertriglyceridemia; LIHC cis rs611744 0.647 rs615126 chr8:109247619 C/T cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC trans rs4566357 0.615 rs12621808 chr2:227909522 A/C cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.6e-9 Coronary artery disease; LIHC cis rs12497850 0.644 rs11928552 chr3:48739883 T/C cg07636037 chr3:49044803 WDR6 0.8 13.11 0.58 4.45e-32 Parkinson's disease; LIHC cis rs6988636 0.901 rs16898076 chr8:124187721 T/C cg15893493 chr8:124194847 FAM83A 0.89 8.31 0.41 2.26e-15 Urinary uromodulin levels; LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.4 0.81 1.02e-80 Prudent dietary pattern; LIHC cis rs16912285 0.688 rs12279442 chr11:24317174 C/G ch.11.24196551F chr11:24239977 NA 0.78 10.4 0.49 3.41e-22 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs919433 0.926 rs787997 chr2:198216271 A/G cg03934865 chr2:198174659 NA 0.54 8.73 0.43 1.14e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs599083 0.530 rs667126 chr11:68177728 C/T cg01657329 chr11:68192670 LRP5 0.6 8.14 0.4 7.2e-15 Bone mineral density (spine); LIHC cis rs9733 0.596 rs72702557 chr1:150680130 A/G cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs7927771 0.524 rs1056387 chr11:47681370 A/C cg20307385 chr11:47447363 PSMC3 0.62 9.36 0.45 1.12e-18 Subjective well-being; LIHC cis rs9457247 1.000 rs406095 chr6:167409087 C/T cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC cis rs600806 0.745 rs12136063 chr1:110014170 A/G cg23091122 chr1:110024289 SYPL2 0.4 5.72 0.3 2.36e-8 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.932 rs11712445 chr3:47434552 T/C cg16586182 chr3:47516702 SCAP -0.58 -10.97 -0.51 3.34e-24 Colorectal cancer; LIHC cis rs7903847 0.642 rs10882910 chr10:99138043 G/A cg06359132 chr10:99160096 RRP12 -0.41 -6.23 -0.32 1.35e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs599083 0.530 rs546803 chr11:68186392 C/T cg01657329 chr11:68192670 LRP5 0.57 7.4 0.37 1.07e-12 Bone mineral density (spine); LIHC cis rs3849570 0.673 rs13068700 chr3:81975817 G/C cg07356753 chr3:81810745 GBE1 -0.53 -8.22 -0.41 4.16e-15 Waist circumference;Body mass index; LIHC cis rs3820500 0.543 rs6676578 chr1:117968957 G/A cg20383390 chr1:117909022 MAN1A2 0.46 5.92 0.3 7.76e-9 Pneumonia; LIHC cis rs2777491 0.957 rs3743038 chr15:41694743 C/T cg18705301 chr15:41695430 NDUFAF1 -0.59 -9.15 -0.44 5.19e-18 Ulcerative colitis; LIHC trans rs9929218 0.954 rs7198799 chr16:68818390 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.67 -0.42 1.82e-16 Colorectal cancer; LIHC cis rs826838 1.000 rs10880914 chr12:38720543 C/T cg13010199 chr12:38710504 ALG10B 0.64 7.89 0.39 4.03e-14 Heart rate; LIHC cis rs12765878 1.000 rs9325507 chr10:105645622 C/T cg11005552 chr10:105648138 OBFC1 0.37 5.79 0.3 1.55e-8 Coronary artery disease; LIHC cis rs12586317 0.620 rs28404080 chr14:35539418 G/T cg16230307 chr14:35515116 FAM177A1 0.8 13.41 0.59 3.01e-33 Psoriasis; LIHC trans rs1005277 0.579 rs2749612 chr10:38488610 G/A cg23533926 chr12:111358616 MYL2 -0.32 -6.12 -0.31 2.61e-9 Extrinsic epigenetic age acceleration; LIHC trans rs7615952 0.866 rs11922276 chr3:125631326 G/T cg07211511 chr3:129823064 LOC729375 -0.84 -10.48 -0.49 1.75e-22 Blood pressure (smoking interaction); LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg09033563 chr22:24373618 LOC391322 0.51 7.21 0.36 3.59e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1048238 0.506 rs10927866 chr1:16175317 C/T cg00529422 chr1:16285251 ZBTB17 -0.34 -6.66 -0.34 1.09e-10 Systolic blood pressure; LIHC cis rs6951245 0.580 rs78894484 chr7:1138721 T/G cg04025307 chr7:1156635 C7orf50 0.64 6.34 0.32 7.25e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11792861 0.781 rs72607158 chr9:111763010 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 8.91 0.43 3.19e-17 Menarche (age at onset); LIHC cis rs507080 0.733 rs552079 chr11:118573022 T/C cg04173919 chr11:118528438 PHLDB1 0.32 6.02 0.31 4.44e-9 Serum metabolite levels; LIHC cis rs9633740 0.947 rs1878036 chr10:82280137 T/G cg01528321 chr10:82214614 TSPAN14 0.93 11.38 0.52 1.13e-25 Post bronchodilator FEV1; LIHC cis rs4319547 0.695 rs12314643 chr12:122917423 C/T cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.18 -0.36 4.29e-12 Body mass index; LIHC cis rs7619427 0.915 rs7625849 chr3:44079200 G/A cg24966902 chr3:44043705 NA 0.51 7.19 0.36 4.09e-12 Schizophrenia; LIHC cis rs9918079 0.560 rs7438356 chr4:15624770 C/T cg21123203 chr4:15471301 CC2D2A -0.47 -7.83 -0.39 6.07e-14 Obesity-related traits; LIHC cis rs72634258 0.554 rs17374292 chr1:7881234 C/T cg00864860 chr1:7907996 UTS2 0.58 5.85 0.3 1.17e-8 Inflammatory bowel disease; LIHC cis rs8044995 0.563 rs7500163 chr16:68364358 C/G cg03983715 chr16:68378420 PRMT7 -0.53 -6.18 -0.32 1.79e-9 Schizophrenia; LIHC cis rs4927850 1.000 rs10881563 chr3:195750225 A/G cg01181863 chr3:195395398 SDHAP2 -0.54 -7.05 -0.36 1.02e-11 Pancreatic cancer; LIHC cis rs6570726 0.967 rs9403707 chr6:145800010 A/G cg23711669 chr6:146136114 FBXO30 0.51 9.05 0.44 1.11e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs4969178 0.965 rs3817295 chr17:76394526 T/A cg20026190 chr17:76395443 PGS1 0.45 7.15 0.36 5.19e-12 HDL cholesterol levels; LIHC cis rs2108622 1.000 rs62107762 chr19:15982538 C/G cg13772218 chr19:15982569 NA 0.41 8.53 0.42 4.66e-16 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs2274273 0.837 rs7142857 chr14:55704128 C/T cg01864836 chr14:55583639 NA -0.43 -8.14 -0.4 7.49e-15 Protein biomarker; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17791867 chr7:112579927 C7orf60 0.45 6.81 0.35 4.35e-11 Cognitive function; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg22704915 chr10:73079101 SLC29A3 -0.45 -6.09 -0.31 3.01e-9 Longevity; LIHC trans rs3812049 0.693 rs9327468 chr5:127441861 C/A cg16011800 chr17:1958478 HIC1 -0.53 -7.47 -0.37 6.95e-13 Lymphocyte counts;Red cell distribution width; LIHC cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.08 0.31 3.13e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7927592 0.913 rs12294029 chr11:68257059 A/C cg01657329 chr11:68192670 LRP5 -0.46 -5.96 -0.31 6.44e-9 Total body bone mineral density; LIHC cis rs10088262 0.629 rs9918907 chr8:124816862 A/G cg20713898 chr8:124780851 FAM91A1 -0.53 -7.19 -0.36 4.2e-12 Pancreatic cancer; LIHC cis rs2153535 0.560 rs9379214 chr6:8480870 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs5753618 0.509 rs1034589 chr22:31579233 C/T cg07713946 chr22:31675144 LIMK2 -0.43 -7.72 -0.39 1.28e-13 Colorectal cancer; LIHC cis rs7129220 0.512 rs7936409 chr11:10086260 A/C cg01453529 chr11:10209919 SBF2 -0.4 -7.0 -0.35 1.32e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs17106184 1.000 rs72904771 chr1:51393412 A/G cg07174182 chr1:51127561 FAF1 -0.75 -7.9 -0.39 3.96e-14 Type 2 diabetes; LIHC cis rs10463316 0.817 rs1508772 chr5:150816561 A/C cg03212797 chr5:150827313 SLC36A1 -0.45 -6.79 -0.34 4.9e-11 Metabolite levels (Pyroglutamine); LIHC cis rs2806561 0.664 rs55764475 chr1:23318983 C/T cg12483005 chr1:23474871 LUZP1 0.43 6.49 0.33 2.97e-10 Height; LIHC cis rs2842992 0.958 rs2758318 chr6:160069637 C/G cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.34 0.52 1.64e-25 Age-related macular degeneration (geographic atrophy); LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg09367891 chr1:107599246 PRMT6 -0.66 -10.88 -0.51 7.36e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9326248 0.954 rs4938349 chr11:117021923 C/T cg01368799 chr11:117014884 PAFAH1B2 0.43 6.17 0.32 1.97e-9 Blood protein levels; LIHC cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg12310025 chr6:25882481 NA -0.61 -8.59 -0.42 3.14e-16 Blood metabolite levels; LIHC cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg11766577 chr21:47581405 C21orf56 -0.44 -7.28 -0.37 2.37e-12 Testicular germ cell tumor; LIHC cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg00684032 chr4:1343700 KIAA1530 0.51 7.39 0.37 1.15e-12 Obesity-related traits; LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg24846343 chr22:24311635 DDTL 0.66 12.3 0.55 4.94e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2637266 0.655 rs846595 chr10:78531300 C/T cg18941641 chr10:78392320 NA 0.28 6.12 0.31 2.52e-9 Pulmonary function; LIHC cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.16 -0.32 2.1e-9 Colorectal cancer; LIHC cis rs17253792 0.908 rs9972177 chr14:56073206 G/A cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs6089829 0.962 rs9679865 chr20:61666132 C/G cg08564027 chr20:61660810 NA 0.4 7.6 0.38 2.91e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg10295955 chr4:187884368 NA -0.96 -22.67 -0.77 4.29e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs858239 0.601 rs6948469 chr7:23174766 G/T cg23682824 chr7:23144976 KLHL7 0.42 6.26 0.32 1.14e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9325144 0.555 rs4882279 chr12:38688918 C/A cg26384229 chr12:38710491 ALG10B 0.6 8.43 0.41 9.62e-16 Morning vs. evening chronotype; LIHC trans rs3749237 1.000 rs2307021 chr3:49765483 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.66 10.28 0.49 8.94e-22 Resting heart rate; LIHC cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs17826219 0.706 rs9893922 chr17:29068425 T/C cg14067834 chr17:29058358 SUZ12P 0.7 7.12 0.36 6.32e-12 Body mass index; LIHC trans rs62103177 0.733 rs62096748 chr18:77619699 T/C cg05926928 chr17:57297772 GDPD1 1.12 11.56 0.53 2.54e-26 Opioid sensitivity; LIHC cis rs10751667 0.643 rs10794343 chr11:925493 C/T ch.11.42038R chr11:967971 AP2A2 0.52 9.47 0.46 4.71e-19 Alzheimer's disease (late onset); LIHC cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg08888203 chr3:10149979 C3orf24 0.59 6.93 0.35 2.13e-11 Alzheimer's disease; LIHC cis rs17685 0.753 rs9691174 chr7:75790405 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.33 -0.32 7.84e-10 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1728785 1.000 rs1728792 chr16:68596534 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.5 0.33 2.82e-10 Ulcerative colitis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25521047 chr19:37341219 ZNF345 0.42 6.37 0.33 5.98e-10 Lung function (FEV1/FVC); LIHC cis rs7249142 0.549 rs2238667 chr19:19282523 G/A cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -6.97 -0.35 1.65e-11 IgG glycosylation; LIHC cis rs9611565 0.592 rs4481089 chr22:41980892 T/C cg03806693 chr22:41940476 POLR3H -0.84 -9.3 -0.45 1.71e-18 Vitiligo; LIHC cis rs9399135 0.967 rs1014020 chr6:135334426 C/A cg24558204 chr6:135376177 HBS1L 0.42 6.96 0.35 1.76e-11 Red blood cell count; LIHC cis rs35110281 0.776 rs2838338 chr21:45075582 T/C cg04455712 chr21:45112962 RRP1B 0.45 7.74 0.39 1.14e-13 Mean corpuscular volume; LIHC cis rs2463822 0.925 rs72923272 chr11:62166832 G/A cg06239285 chr11:62104954 ASRGL1 -0.86 -5.78 -0.3 1.71e-8 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg18252515 chr7:66147081 NA -1.23 -15.85 -0.65 8.1e-43 Diabetic kidney disease; LIHC cis rs644799 0.965 rs10831425 chr11:95500628 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.5 0.69 2.02e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7572733 0.555 rs7561950 chr2:198754244 C/T cg00792783 chr2:198669748 PLCL1 0.45 6.61 0.34 1.5e-10 Dermatomyositis; LIHC cis rs1559088 0.749 rs10405757 chr19:33616526 C/A cg27124370 chr19:33622961 WDR88 0.53 8.38 0.41 1.38e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs1005277 0.579 rs1780145 chr10:38537070 A/G cg17830980 chr10:43048298 ZNF37B -0.52 -9.97 -0.47 1.01e-20 Extrinsic epigenetic age acceleration; LIHC cis rs7208859 0.673 rs9896095 chr17:29187497 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7917772 0.636 rs2250580 chr10:104505687 C/G cg22532475 chr10:104410764 TRIM8 -0.34 -6.34 -0.32 7.41e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6723226 0.804 rs17428810 chr2:32736043 T/C cg02381751 chr2:32503542 YIPF4 -0.79 -12.23 -0.55 8.49e-29 Intelligence (multi-trait analysis); LIHC cis rs11252926 0.801 rs12358553 chr10:558014 C/T cg16346588 chr10:242978 ZMYND11 -0.47 -5.84 -0.3 1.2e-8 Psychosis in Alzheimer's disease; LIHC cis rs477895 1.000 rs11600990 chr11:64082807 C/T cg18225595 chr11:63971243 STIP1 0.59 5.76 0.3 1.85e-8 Mean platelet volume; LIHC cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg16482183 chr6:26056742 HIST1H1C 0.36 5.73 0.3 2.24e-8 Height; LIHC trans rs9929218 0.911 rs4783685 chr16:68834107 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -8.09 -0.4 1.04e-14 Colorectal cancer; LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg18538332 chr22:24372958 LOC391322 -0.5 -6.83 -0.35 3.78e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.73 0.62 2.3e-38 Prudent dietary pattern; LIHC cis rs546131 0.642 rs7131074 chr11:34839105 G/T cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.49 -0.33 3.05e-10 Lung disease severity in cystic fibrosis; LIHC cis rs35306767 1.000 rs35306767 chr10:989437 A/T cg26597838 chr10:835615 NA 1.08 10.66 0.5 4.13e-23 Eosinophil percentage of granulocytes; LIHC trans rs11098499 0.954 rs13113483 chr4:120309039 C/T cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22546437 chr19:47987707 KPTN 0.45 6.26 0.32 1.16e-9 Pancreatic cancer; LIHC cis rs9658691 0.607 rs9325604 chr10:90775756 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.88 -6.65 -0.34 1.15e-10 Mosquito bite size; LIHC cis rs9399135 0.636 rs7749106 chr6:135268142 G/A cg24558204 chr6:135376177 HBS1L 0.43 6.83 0.35 3.92e-11 Red blood cell count; LIHC cis rs7520050 0.966 rs1707304 chr1:46598269 C/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.73 0.3 2.26e-8 Red blood cell count;Reticulocyte count; LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg07092213 chr7:1199455 ZFAND2A -0.46 -6.99 -0.35 1.43e-11 Longevity;Endometriosis; LIHC cis rs9372253 0.818 rs2207360 chr6:110706337 G/C cg01119278 chr6:110721349 DDO -0.32 -6.71 -0.34 8.11e-11 Platelet distribution width; LIHC trans rs9291683 0.668 rs2241474 chr4:10086015 T/C cg26043149 chr18:55253948 FECH 0.39 6.39 0.33 5.56e-10 Bone mineral density; LIHC cis rs1348850 0.914 rs6710575 chr2:178377311 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.37 0.59 4.28e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9309473 0.687 rs6747145 chr2:73609177 C/T cg20560298 chr2:73613845 ALMS1 -0.48 -7.62 -0.38 2.51e-13 Metabolite levels; LIHC cis rs1577917 0.740 rs7752502 chr6:86410651 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.49 9.77 0.47 4.63e-20 Response to antipsychotic treatment; LIHC cis rs8067354 0.645 rs28516945 chr17:57816578 T/C cg13753209 chr17:57696993 CLTC 0.72 11.22 0.52 4.32e-25 Hemoglobin concentration; LIHC cis rs2976388 0.556 rs4736323 chr8:143830359 C/T cg06565975 chr8:143823917 SLURP1 -0.43 -7.4 -0.37 1.07e-12 Urinary tract infection frequency; LIHC cis rs400736 0.671 rs863171 chr1:7992615 A/G cg25007680 chr1:8021821 PARK7 0.43 6.89 0.35 2.65e-11 Response to antidepressants and depression; LIHC cis rs7843479 0.544 rs11135735 chr8:21791557 C/T cg17168535 chr8:21777572 XPO7 0.6 10.93 0.51 4.83e-24 Mean corpuscular volume; LIHC cis rs9640161 0.783 rs35435439 chr7:150063534 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.15 -0.4 6.88e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg12379764 chr21:47803548 PCNT -0.59 -8.56 -0.42 3.92e-16 Testicular germ cell tumor; LIHC cis rs6952808 0.531 rs73039217 chr7:2178731 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.87 -0.3 1.01e-8 Bipolar disorder and schizophrenia; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.54 7.58 0.38 3.18e-13 Lymphocyte counts; LIHC cis rs11758351 0.778 rs41266801 chr6:26197493 C/A cg03854865 chr6:26224070 HIST1H3E 0.64 7.15 0.36 5.46e-12 Gout;Renal underexcretion gout; LIHC cis rs7208859 0.673 rs56846352 chr17:29119188 C/T cg14067834 chr17:29058358 SUZ12P 0.66 6.65 0.34 1.18e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12477438 0.765 rs6737257 chr2:99683330 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs1451375 0.794 rs11238134 chr7:50542927 A/C cg14593290 chr7:50529359 DDC -0.45 -7.43 -0.37 8.79e-13 Malaria; LIHC trans rs1945213 0.694 rs1384088 chr11:55848713 G/C cg03929089 chr4:120376271 NA -0.53 -6.78 -0.34 5.19e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs1997103 0.954 rs6593222 chr7:55372932 A/C cg17469321 chr7:55412551 NA 0.48 7.0 0.35 1.37e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2243480 0.901 rs73142137 chr7:65343442 A/T cg05590025 chr7:65112418 INTS4L2 -0.6 -6.45 -0.33 3.93e-10 Diabetic kidney disease; LIHC cis rs16828019 0.929 rs12037037 chr1:41698256 C/T cg20697417 chr1:41786797 NA 0.34 6.51 0.33 2.61e-10 Intelligence (multi-trait analysis); LIHC cis rs7617480 0.648 rs14018 chr3:48784270 G/A cg07636037 chr3:49044803 WDR6 0.76 9.01 0.44 1.49e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs1371867 0.875 rs962452 chr8:101331369 G/A cg06636551 chr8:101224915 SPAG1 -0.47 -8.72 -0.43 1.26e-16 Atrioventricular conduction; LIHC cis rs7577696 0.597 rs56322034 chr2:32353013 T/C cg02381751 chr2:32503542 YIPF4 -0.45 -6.2 -0.32 1.62e-9 Inflammatory biomarkers; LIHC cis rs9942416 0.660 rs60423072 chr5:75006113 T/A cg19683494 chr5:74908142 NA 0.49 6.58 0.34 1.76e-10 Age-related disease endophenotypes; LIHC cis rs2242116 1.000 rs2168443 chr3:46947087 A/T cg23352942 chr3:46931381 PTH1R 0.24 6.06 0.31 3.66e-9 Birth weight; LIHC cis rs12144044 0.701 rs2999159 chr1:113230758 A/G cg22162597 chr1:113214053 CAPZA1 -0.7 -8.35 -0.41 1.73e-15 Glomerular filtration rate (creatinine); LIHC cis rs1018836 0.892 rs2187981 chr8:91549629 T/C cg16814680 chr8:91681699 NA -0.58 -9.56 -0.46 2.37e-19 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs3015497 0.789 rs10133849 chr14:51121700 A/G cg09863266 chr14:51125203 SAV1 -0.42 -6.73 -0.34 7.35e-11 Mean platelet volume; LIHC cis rs9467773 1.000 rs6456733 chr6:26566804 C/T cg11502198 chr6:26597334 ABT1 0.45 6.51 0.33 2.64e-10 Intelligence (multi-trait analysis); LIHC cis rs2302190 0.769 rs8082396 chr17:56632193 C/T cg05425664 chr17:57184151 TRIM37 -0.46 -5.76 -0.3 1.83e-8 Vitamin D levels; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.76 -14.43 -0.62 3.29e-37 Prudent dietary pattern; LIHC cis rs12210905 0.800 rs12209651 chr6:26660925 A/C cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Hip circumference adjusted for BMI; LIHC cis rs7149337 0.869 rs7159770 chr14:51691835 G/A cg23942311 chr14:51606299 NA 0.31 6.16 0.32 2.02e-9 Cancer; LIHC cis rs1816752 0.789 rs7986037 chr13:25012853 A/G cg22771759 chr13:24902376 NA 0.33 6.93 0.35 2.07e-11 Obesity-related traits; LIHC cis rs797680 0.856 rs9432681 chr1:93761896 A/G cg15093775 chr1:93646470 TMED5;CCDC18 0.34 6.06 0.31 3.5e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs9902453 0.874 rs62070271 chr17:28268358 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.99 0.6 1.73e-35 Coffee consumption (cups per day); LIHC cis rs4713118 0.666 rs4140646 chr6:27738801 G/A cg20933634 chr6:27740509 NA 0.48 6.26 0.32 1.15e-9 Parkinson's disease; LIHC cis rs870825 0.860 rs28799091 chr4:185598594 G/A cg04058563 chr4:185651563 MLF1IP 0.78 6.95 0.35 1.83e-11 Blood protein levels; LIHC cis rs11190604 1.000 rs57025426 chr10:102205868 A/G cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg02782426 chr3:40428986 ENTPD3 -0.35 -6.47 -0.33 3.46e-10 Renal cell carcinoma; LIHC cis rs651907 0.557 rs17347644 chr3:101547733 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.68 11.15 0.52 7.94e-25 Colorectal cancer; LIHC cis rs875971 1.000 rs4718344 chr7:65874381 C/A cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs637571 0.522 rs566590 chr11:65754062 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.41 6.18 0.32 1.8e-9 Eosinophil percentage of white cells; LIHC cis rs6495122 0.532 rs2472304 chr15:75044238 G/A cg14664628 chr15:75095509 CSK -0.53 -7.35 -0.37 1.49e-12 Caffeine consumption;Diastolic blood pressure;Coffee consumption; LIHC cis rs6684514 1.000 rs10908502 chr1:156300082 A/G cg16558208 chr1:156270281 VHLL 0.54 10.31 0.49 7.15e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg18404041 chr3:52824283 ITIH1 -0.58 -9.67 -0.46 1e-19 Electroencephalogram traits; LIHC cis rs10197940 0.662 rs4467261 chr2:152281391 G/C cg06191203 chr2:152266755 RIF1 -0.46 -7.8 -0.39 7.5e-14 Lung cancer; LIHC cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg26831259 chr4:1366826 KIAA1530 0.35 5.79 0.3 1.63e-8 Obesity-related traits; LIHC cis rs8084351 0.599 rs12454147 chr18:50707053 G/T cg24270629 chr18:50823537 DCC -0.43 -6.32 -0.32 8.15e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs11711311 0.911 rs9817327 chr3:113478500 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.94 -0.35 2e-11 IgG glycosylation; LIHC cis rs72781680 0.898 rs7569424 chr2:24036222 A/G cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs2455799 0.593 rs2047852 chr3:15732539 T/G cg12698662 chr3:15914712 MIR563 -0.37 -6.89 -0.35 2.64e-11 Mean platelet volume; LIHC cis rs9326248 1.000 rs4938344 chr11:117003749 G/A cg11861562 chr11:117069780 TAGLN 0.47 7.7 0.38 1.48e-13 Blood protein levels; LIHC cis rs1707322 0.752 rs6703748 chr1:46095976 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.55 0.38 4.08e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs637571 0.607 rs574586 chr11:65697083 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.4 0.41 1.21e-15 Eosinophil percentage of white cells; LIHC cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg24209194 chr3:40518798 ZNF619 0.48 7.12 0.36 6.53e-12 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06096824 chr1:51443952 NA -0.45 -6.1 -0.31 2.86e-9 Pancreatic cancer; LIHC cis rs174551 1 rs174551 chr11:61573684 T/C cg27386326 chr11:61587980 NA 0.7 14.83 0.63 9.05e-39 LDL cholesterol; LIHC cis rs1008375 0.900 rs6812675 chr4:17597549 A/G cg16339924 chr4:17578868 LAP3 0.53 7.14 0.36 5.79e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6519955 0.765 rs7292527 chr22:46423125 G/T cg00209037 chr22:46443395 NA 0.65 8.14 0.4 7.37e-15 Dupuytren's disease; LIHC cis rs9300255 0.620 rs1727311 chr12:123660716 T/G cg00376283 chr12:123451042 ABCB9 0.58 5.72 0.3 2.3e-8 Neutrophil percentage of white cells; LIHC cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.8 15.13 0.63 5.95e-40 Menarche (age at onset); LIHC cis rs7927771 0.832 rs7940536 chr11:47395240 G/A cg20307385 chr11:47447363 PSMC3 0.44 5.78 0.3 1.68e-8 Subjective well-being; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20278634 chr1:36274212 EIF2C4 -0.53 -6.48 -0.33 3.11e-10 Systolic blood pressure; LIHC trans rs1814175 0.546 rs1614397 chr11:49913384 G/C cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs17106184 0.892 rs72900928 chr1:51103180 T/G cg07174182 chr1:51127561 FAF1 -0.65 -7.04 -0.36 1.03e-11 Type 2 diabetes; LIHC cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2228479 0.618 rs34689166 chr16:89860697 C/T cg00800038 chr16:89945340 TCF25 -0.61 -8.68 -0.42 1.69e-16 Skin colour saturation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14347670 chr6:41908995 CCND3 0.41 6.68 0.34 9.48e-11 Cognitive function; LIHC trans rs6489882 0.607 rs4767033 chr12:113364382 T/A cg10175203 chr3:128143634 NA 0.39 6.39 0.33 5.57e-10 Chronic lymphocytic leukemia; LIHC trans rs7504990 0.722 rs12958987 chr18:50359002 G/T cg08535148 chr4:26321143 RBPJ 0.52 6.64 0.34 1.21e-10 Gallbladder cancer; LIHC cis rs11792861 0.926 rs11788904 chr9:111865052 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.64e-16 Menarche (age at onset); LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg11235426 chr6:292522 DUSP22 -0.56 -7.82 -0.39 6.52e-14 Menopause (age at onset); LIHC cis rs8020095 0.528 rs1044745 chr14:67800815 G/A cg03487553 chr14:67822707 ATP6V1D -0.35 -6.02 -0.31 4.55e-9 Depression (quantitative trait); LIHC cis rs62380364 0.602 rs606393 chr5:88058163 T/C cg22951263 chr5:87985283 NA -0.41 -7.09 -0.36 7.72e-12 Intelligence (multi-trait analysis); LIHC cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.62 5.9 0.3 8.78e-9 Platelet count; LIHC cis rs539514 0.612 rs9573648 chr13:76309279 A/G cg04757411 chr13:76259545 LMO7 -0.45 -8.06 -0.4 1.3e-14 Type 1 diabetes; LIHC cis rs6500602 0.826 rs11076830 chr16:4460049 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.45 6.41 0.33 4.89e-10 Schizophrenia; LIHC cis rs10876993 0.928 rs1678540 chr12:58065002 A/G cg18357645 chr12:58087776 OS9 0.51 8.45 0.42 8.61e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs7927771 1.000 rs11039426 chr11:47863119 G/A cg20135002 chr11:47629003 NA -0.53 -8.97 -0.44 1.94e-17 Subjective well-being; LIHC cis rs3749237 0.595 rs3924462 chr3:49524236 T/G cg03060546 chr3:49711283 APEH 0.63 10.23 0.48 1.35e-21 Resting heart rate; LIHC cis rs240764 0.619 rs10872623 chr6:101165047 A/G cg09795085 chr6:101329169 ASCC3 -0.42 -6.03 -0.31 4.27e-9 Neuroticism; LIHC cis rs523522 0.962 rs9788155 chr12:120938408 G/A cg27279351 chr12:120934652 DYNLL1 0.67 12.05 0.55 3.99e-28 High light scatter reticulocyte count; LIHC cis rs55665837 0.540 rs12290926 chr11:14695046 A/G cg25251204 chr11:14927456 NA 0.42 5.95 0.31 6.48e-9 Vitamin D levels; LIHC cis rs2251381 0.778 rs2245021 chr21:30546841 C/T cg08807101 chr21:30365312 RNF160 0.76 9.89 0.47 1.91e-20 Selective IgA deficiency; LIHC cis rs7615952 0.932 rs1976458 chr3:125647512 T/G cg05084668 chr3:125655381 ALG1L -0.6 -8.61 -0.42 2.76e-16 Blood pressure (smoking interaction); LIHC cis rs6951245 1.000 rs884977 chr7:1066410 T/C cg24642844 chr7:1081250 C7orf50 -0.65 -7.06 -0.36 9.41e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs600806 0.850 rs2140924 chr1:109935775 A/C cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.17 -0.36 4.54e-12 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.647 rs8025991 chr15:77155268 C/T cg23625390 chr15:77176239 SCAPER -0.57 -9.76 -0.47 5.37e-20 Blood metabolite levels; LIHC cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg00934597 chr7:893267 UNC84A 0.61 9.13 0.44 6.16e-18 Perceived unattractiveness to mosquitoes; LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg26338869 chr17:61819248 STRADA -0.52 -7.12 -0.36 6.46e-12 Height; LIHC cis rs2204008 0.748 rs8186658 chr12:38301461 A/C cg26384229 chr12:38710491 ALG10B 0.58 8.19 0.41 5.15e-15 Bladder cancer; LIHC cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.68 0.57 1.91e-30 Alzheimer's disease; LIHC cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg24549020 chr5:56110836 MAP3K1 0.5 6.41 0.33 4.95e-10 Initial pursuit acceleration; LIHC cis rs3806843 1.000 rs3756339 chr5:140180537 A/G cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.21e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs6754311 0.773 rs4988183 chr2:136622046 T/C cg15123519 chr2:136567270 LCT -0.37 -7.39 -0.37 1.14e-12 Mosquito bite size; LIHC cis rs1866706 0.896 rs7945921 chr11:12875794 C/A cg25843174 chr11:12811716 TEAD1 -0.29 -6.08 -0.31 3.13e-9 Intelligence (multi-trait analysis); LIHC cis rs7715806 0.500 rs58968428 chr5:75004107 A/G cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10751667 0.666 rs10902243 chr11:949900 T/C cg10932868 chr11:921992 NA 0.39 7.31 0.37 1.89e-12 Alzheimer's disease (late onset); LIHC cis rs7914558 1.000 rs7920251 chr10:104950197 C/T cg15744005 chr10:104629667 AS3MT -0.38 -8.47 -0.42 7.4e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2304069 0.954 rs10068537 chr5:149403193 G/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.94 12.06 0.55 3.84e-28 HIV-1 control; LIHC cis rs3768617 0.811 rs10797828 chr1:183028430 G/A ch.1.3577855R chr1:183094577 LAMC1 0.48 7.57 0.38 3.6e-13 Fuchs's corneal dystrophy; LIHC cis rs765787 0.505 rs11630884 chr15:45532246 C/T cg24006582 chr15:45444508 DUOX1 -0.53 -7.7 -0.38 1.5e-13 Uric acid levels; LIHC cis rs6582630 0.519 rs11181998 chr12:38439970 C/A cg26384229 chr12:38710491 ALG10B 0.61 8.48 0.42 6.79e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs17401966 0.931 rs10492972 chr1:10353112 A/G cg19773385 chr1:10388646 KIF1B -0.39 -7.0 -0.35 1.35e-11 Hepatocellular carcinoma; LIHC cis rs709400 0.930 rs57447494 chr14:104034569 G/A cg26031613 chr14:104095156 KLC1 1.11 13.94 0.6 2.76e-35 Body mass index; LIHC cis rs1707322 1.000 rs10890359 chr1:46336635 A/G cg06784218 chr1:46089804 CCDC17 0.37 6.53 0.33 2.37e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg27170947 chr2:26402098 FAM59B -0.51 -6.66 -0.34 1.12e-10 Gut microbiome composition (summer); LIHC cis rs965469 1.000 rs2092990 chr20:3346338 C/T cg25506879 chr20:3388711 C20orf194 -0.55 -6.51 -0.33 2.73e-10 IFN-related cytopenia; LIHC cis rs921968 0.565 rs4674328 chr2:219593203 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.44 -0.33 4.15e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs919433 0.817 rs10931780 chr2:198175297 G/C cg10820045 chr2:198174542 NA -0.6 -10.04 -0.48 5.91e-21 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg06640241 chr16:89574553 SPG7 0.68 11.07 0.51 1.53e-24 Multiple myeloma (IgH translocation); LIHC cis rs2075371 0.933 rs1833475 chr7:133958263 C/T cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.68e-14 Mean platelet volume; LIHC cis rs903552 0.800 rs6598479 chr15:102005913 A/C cg19295451 chr15:102010161 PCSK6 -0.5 -6.79 -0.34 5.09e-11 Diabetic kidney disease; LIHC cis rs2439831 0.681 rs7176849 chr15:43681427 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.73 10.62 0.5 6.05e-23 Lung cancer in ever smokers; LIHC cis rs4906332 1.000 rs2065018 chr14:103879187 C/T cg04998671 chr14:104000505 TRMT61A 0.46 6.47 0.33 3.33e-10 Coronary artery disease; LIHC cis rs8180040 0.726 rs4078466 chr3:47126543 C/T cg27129171 chr3:47204927 SETD2 0.69 12.16 0.55 1.55e-28 Colorectal cancer; LIHC cis rs7044106 0.791 rs4837793 chr9:123483621 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.73 11.8 0.54 3.31e-27 Hip circumference adjusted for BMI; LIHC cis rs11212260 0.512 rs79797517 chr11:107173777 T/C cg25435332 chr11:107328525 CWF19L2 0.73 6.69 0.34 9.13e-11 IgG glycosylation; LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 9.04e-33 Prudent dietary pattern; LIHC cis rs769267 0.930 rs4808208 chr19:19650096 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.07 0.31 3.39e-9 Tonsillectomy; LIHC cis rs2070488 0.932 rs1841776 chr3:38480727 C/T cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC cis rs9470366 0.545 rs4711457 chr6:36633160 T/C cg00935119 chr6:36647544 CDKN1A 0.46 6.5 0.33 2.92e-10 QRS duration; LIHC cis rs9309473 0.898 rs10197755 chr2:73797623 T/A cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs6456156 0.586 rs1407315 chr6:167468659 A/G cg12798992 chr6:167411361 FGFR1OP 0.44 6.8 0.34 4.81e-11 Primary biliary cholangitis; LIHC cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg02564969 chr6:151773285 C6orf211;RMND1 0.52 7.99 0.4 2.09e-14 Menarche (age at onset); LIHC cis rs3762637 1.000 rs28497203 chr3:122231819 T/C cg24169773 chr3:122142474 KPNA1 -0.47 -9.13 -0.44 6.09e-18 LDL cholesterol levels; LIHC cis rs67460515 0.563 rs11717272 chr3:160810355 A/G cg03342759 chr3:160939853 NMD3 -0.58 -8.29 -0.41 2.6e-15 Parkinson's disease; LIHC cis rs4853012 0.941 rs2421752 chr2:74341615 A/G cg23149560 chr2:74406255 MOBKL1B 0.41 5.74 0.3 2.05e-8 Gestational age at birth (maternal effect); LIHC cis rs10751667 0.666 rs10902241 chr11:949129 G/A cg10932868 chr11:921992 NA 0.39 7.31 0.37 1.89e-12 Alzheimer's disease (late onset); LIHC cis rs7927592 0.956 rs12274114 chr11:68255577 A/C cg01657329 chr11:68192670 LRP5 -0.46 -5.94 -0.31 7.03e-9 Total body bone mineral density; LIHC cis rs317689 0.690 rs317656 chr12:69681101 T/A cg22834771 chr12:69754056 YEATS4 -0.4 -6.01 -0.31 4.64e-9 Response to diuretic therapy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24865495 chr11:63912769 MACROD1 -0.4 -6.21 -0.32 1.5e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2901460 0.509 rs12465313 chr2:62078301 G/A cg02183531 chr2:62113199 CCT4 -0.42 -6.09 -0.31 3.09e-9 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg12463550 chr7:65579703 CRCP 0.71 7.42 0.37 9.62e-13 Diabetic kidney disease; LIHC cis rs9810089 0.708 rs619605 chr3:136087012 G/C cg21827317 chr3:136751795 NA 0.43 5.84 0.3 1.22e-8 Gestational age at birth (child effect); LIHC cis rs17376456 0.877 rs10044139 chr5:93407803 T/C cg25358565 chr5:93447407 FAM172A 1.12 10.25 0.48 1.1e-21 Diabetic retinopathy; LIHC trans rs1814175 0.527 rs10769595 chr11:49638212 A/G cg18944383 chr4:111397179 ENPEP 0.32 7.4 0.37 1.03e-12 Height; LIHC trans rs1005277 0.557 rs1854563 chr10:38434961 G/A cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1448094 0.512 rs6539933 chr12:86247611 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.33 0.32 7.76e-10 Major depressive disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19455953 chr2:207630073 FASTKD2;MDH1B 0.36 6.34 0.32 7.39e-10 Cognitive function; LIHC cis rs7208859 0.673 rs216410 chr17:28903831 C/G cg14067834 chr17:29058358 SUZ12P -0.62 -6.33 -0.32 7.89e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6952808 0.572 rs1860826 chr7:2112506 G/A cg21782813 chr7:2030301 MAD1L1 0.43 7.3 0.37 2e-12 Bipolar disorder and schizophrenia; LIHC trans rs7677751 0.806 rs4864863 chr4:55100831 A/G cg17183009 chr3:120277827 NA 0.52 6.08 0.31 3.18e-9 Corneal astigmatism; LIHC cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs3824867 0.920 rs80241400 chr11:47453828 T/C cg20307385 chr11:47447363 PSMC3 -0.58 -7.96 -0.4 2.62e-14 Mean corpuscular hemoglobin; LIHC cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg24549020 chr5:56110836 MAP3K1 0.52 6.64 0.34 1.23e-10 Initial pursuit acceleration; LIHC cis rs3789045 0.826 rs12040520 chr1:204564762 G/A cg17419461 chr1:204415978 PIK3C2B -0.39 -6.07 -0.31 3.47e-9 Educational attainment (college completion); LIHC cis rs7833790 0.660 rs67666182 chr8:82772037 A/G cg02079420 chr8:82753780 SNX16 -0.36 -6.64 -0.34 1.21e-10 Diastolic blood pressure; LIHC cis rs1355223 0.902 rs34751755 chr11:34694243 C/T cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.07 -0.31 3.3e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg16434002 chr17:42200994 HDAC5 -0.53 -7.67 -0.38 1.78e-13 Total body bone mineral density; LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg11060661 chr22:24314208 DDT;DDTL 0.68 12.06 0.55 3.63e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12477438 1.000 rs17760953 chr2:99859863 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -9.75 -0.47 5.45e-20 Chronic sinus infection; LIHC cis rs67460515 0.563 rs68166680 chr3:160829735 T/A cg17135325 chr3:160939158 NMD3 0.55 7.85 0.39 5.36e-14 Parkinson's disease; LIHC cis rs11864453 0.963 rs7185215 chr16:72034864 T/C cg16558253 chr16:72132732 DHX38 -0.41 -5.72 -0.3 2.27e-8 Fibrinogen levels; LIHC cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg13395646 chr4:1353034 KIAA1530 -0.66 -9.55 -0.46 2.64e-19 Obesity-related traits; LIHC cis rs12995491 0.933 rs13023008 chr2:88530933 G/A cg04511125 chr2:88470314 THNSL2 -0.42 -6.38 -0.33 5.63e-10 Response to metformin (IC50); LIHC cis rs12586317 0.547 rs10130773 chr14:35445299 G/A cg16230307 chr14:35515116 FAM177A1 0.77 12.8 0.57 6.22e-31 Psoriasis; LIHC cis rs2197308 0.619 rs4002730 chr12:37876400 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs9910055 0.530 rs2269905 chr17:42294462 A/G cg08499158 chr17:42289980 UBTF -0.48 -7.72 -0.39 1.33e-13 Total body bone mineral density; LIHC cis rs2204008 0.774 rs7304438 chr12:38361146 T/G cg26384229 chr12:38710491 ALG10B 0.57 7.83 0.39 6.11e-14 Bladder cancer; LIHC cis rs713477 0.967 rs1572613 chr14:55909897 C/T cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.32e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs67460515 0.892 rs11711695 chr3:161057593 A/G cg03342759 chr3:160939853 NMD3 -0.55 -8.23 -0.41 4.08e-15 Parkinson's disease; LIHC cis rs1801251 1.000 rs3817311 chr2:233612557 C/T cg25237894 chr2:233734115 C2orf82 0.58 11.15 0.52 7.7e-25 Coronary artery disease; LIHC cis rs6089829 0.962 rs6062780 chr20:61666648 T/C cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs1005277 0.540 rs2474598 chr10:38430296 C/T cg03665457 chr10:38645376 HSD17B7P2 0.4 5.93 0.31 7.25e-9 Extrinsic epigenetic age acceleration; LIHC cis rs722599 0.628 rs12896360 chr14:75278181 A/C cg11812906 chr14:75593930 NEK9 0.38 5.88 0.3 9.97e-9 IgG glycosylation; LIHC cis rs6964587 0.900 rs62467794 chr7:91850578 C/T cg17063962 chr7:91808500 NA 0.98 15.36 0.64 7.67e-41 Breast cancer; LIHC cis rs8016982 0.617 rs2241621 chr14:81737076 G/T cg01989461 chr14:81687754 GTF2A1 -0.54 -10.41 -0.49 3.25e-22 Schizophrenia; LIHC cis rs17401966 1.000 rs60743860 chr1:10442926 G/C cg19773385 chr1:10388646 KIF1B -0.46 -7.54 -0.38 4.14e-13 Hepatocellular carcinoma; LIHC cis rs709400 0.633 rs8013101 chr14:103951772 G/C cg26031613 chr14:104095156 KLC1 0.7 9.03 0.44 1.26e-17 Body mass index; LIHC cis rs11190604 1.000 rs9420797 chr10:102331147 C/T cg07080220 chr10:102295463 HIF1AN 0.54 7.8 0.39 7.46e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg21644426 chr2:191273491 MFSD6 0.53 7.49 0.38 6.06e-13 Pulse pressure; LIHC cis rs798554 0.959 rs798556 chr7:2759002 C/A cg19717773 chr7:2847554 GNA12 -0.39 -6.04 -0.31 4.07e-9 Height; LIHC cis rs9443189 0.570 rs276687 chr6:76429995 G/T cg01950844 chr6:76311363 SENP6 -0.83 -9.57 -0.46 2.19e-19 Prostate cancer; LIHC cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg23172400 chr8:95962367 TP53INP1 -0.44 -10.28 -0.49 8.58e-22 Type 2 diabetes; LIHC cis rs9326248 0.911 rs11216284 chr11:117003060 C/T cg10130564 chr11:117069849 TAGLN 0.35 6.0 0.31 4.89e-9 Blood protein levels; LIHC cis rs238295 0.805 rs6085211 chr20:5552847 G/C cg24001556 chr20:5591874 RP5-1022P6.2 -0.53 -7.19 -0.36 4.16e-12 Occipital cortical area (total cortical area interaction); LIHC cis rs7572733 0.534 rs13026569 chr2:198783330 C/G cg03934865 chr2:198174659 NA -0.46 -6.7 -0.34 8.86e-11 Dermatomyositis; LIHC cis rs748404 0.578 rs512628 chr15:43618734 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.57 9.15 0.44 5.34e-18 Lung cancer; LIHC cis rs644799 0.965 rs3789960 chr11:95509037 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.26 0.68 1.94e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11711311 1.000 rs1043132 chr3:113528689 A/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.47 8.87 0.43 4.28e-17 IgG glycosylation; LIHC cis rs6669384 0.774 rs7551724 chr1:208030856 C/T cg22525895 chr1:207977042 MIR29B2 -0.52 -6.05 -0.31 3.88e-9 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs2075371 0.835 rs1646724 chr7:134001875 T/G cg20476274 chr7:133979776 SLC35B4 0.71 11.76 0.54 4.65e-27 Mean platelet volume; LIHC cis rs1185460 0.565 rs540261 chr11:118947634 C/T cg23280166 chr11:118938394 VPS11 -0.44 -5.79 -0.3 1.62e-8 Coronary artery disease; LIHC cis rs3768617 0.510 rs1886500 chr1:183095048 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs1799949 0.965 rs7212284 chr17:41205941 A/G cg23758822 chr17:41437982 NA 0.89 16.31 0.66 1.16e-44 Menopause (age at onset); LIHC cis rs4665809 0.759 rs62128394 chr2:26364026 T/G cg27170947 chr2:26402098 FAM59B 0.64 6.72 0.34 7.68e-11 Gut microbiome composition (summer); LIHC cis rs2073300 1.000 rs12625160 chr20:23442008 T/C cg12062639 chr20:23401060 NAPB 0.85 10.0 0.48 7.79e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs1814175 0.817 rs10769648 chr11:50013992 T/C cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC cis rs17685 0.753 rs2302435 chr7:75676987 G/A cg04610667 chr7:75704037 NA 0.35 6.12 0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2191566 0.960 rs56171514 chr19:44506110 G/C cg20607764 chr19:44506953 ZNF230 -0.38 -5.93 -0.31 7.43e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs7833790 0.660 rs1451995 chr8:82746123 G/C cg27398817 chr8:82754497 SNX16 0.32 5.82 0.3 1.36e-8 Diastolic blood pressure; LIHC cis rs10791097 0.592 rs7116068 chr11:130732739 A/C cg12179176 chr11:130786555 SNX19 -0.81 -13.49 -0.59 1.55e-33 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4788570 0.584 rs11075898 chr16:71705215 T/C cg06353428 chr16:71660113 MARVELD3 1.39 14.48 0.62 2.14e-37 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.601 rs9505473 chr6:8538777 T/C cg07606381 chr6:8435919 SLC35B3 0.78 11.28 0.52 2.74e-25 Motion sickness; LIHC cis rs6762477 0.748 rs11717349 chr3:50223977 C/T cg21467203 chr3:49911342 NA 0.37 6.44 0.33 4.06e-10 Menarche (age at onset); LIHC cis rs1153858 1.000 rs4775911 chr15:45649787 G/T cg14582100 chr15:45693742 SPATA5L1 -0.34 -6.78 -0.34 5.26e-11 Homoarginine levels; LIHC cis rs1008375 1.000 rs2286771 chr4:17643848 G/A cg02297831 chr4:17616191 MED28 0.49 7.79 0.39 7.98e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs763121 0.785 rs5750646 chr22:39013830 T/C cg14440974 chr22:39074834 NA -0.35 -5.76 -0.3 1.92e-8 Menopause (age at onset); LIHC cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg02244288 chr16:89573955 SPG7 -0.3 -5.76 -0.3 1.85e-8 Multiple myeloma (IgH translocation); LIHC cis rs1577917 1.000 rs10944170 chr6:86685469 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -9.95 -0.47 1.15e-20 Response to antipsychotic treatment; LIHC cis rs1499614 1.000 rs2707830 chr7:66167645 T/C cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC trans rs2727020 0.729 rs10839283 chr11:49490943 T/C cg03929089 chr4:120376271 NA 0.74 11.99 0.54 7.03e-28 Coronary artery disease; LIHC cis rs3020736 0.500 rs28791586 chr22:42500483 A/G cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg02592271 chr2:27665507 KRTCAP3 -0.46 -6.41 -0.33 4.78e-10 Total body bone mineral density; LIHC cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.87 7.75 0.39 1.07e-13 Platelet count; LIHC cis rs74233809 1.000 rs11191502 chr10:104765494 T/G cg03493300 chr10:104813866 CNNM2 0.45 6.06 0.31 3.69e-9 Birth weight; LIHC cis rs7959452 0.535 rs11177577 chr12:69671791 C/T cg20891283 chr12:69753455 YEATS4 0.8 14.91 0.63 4.23e-39 Blood protein levels; LIHC cis rs1419980 0.722 rs752452 chr12:7781021 G/A cg14906510 chr12:7781169 NA 0.48 7.38 0.37 1.25e-12 HDL cholesterol levels; LIHC cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg03264133 chr6:25882463 NA 0.54 7.14 0.36 5.59e-12 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg21747090 chr2:27597821 SNX17 -0.44 -6.55 -0.33 2.17e-10 Total body bone mineral density; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.7 10.01 0.48 7.71e-21 Lymphocyte counts; LIHC cis rs7959452 0.527 rs4761157 chr12:69780907 A/G cg22834771 chr12:69754056 YEATS4 -0.52 -9.23 -0.45 2.82e-18 Blood protein levels; LIHC cis rs10781543 0.839 rs10870071 chr9:139382184 T/C cg13856295 chr9:139396418 NOTCH1 -0.34 -5.74 -0.3 2.14e-8 Monocyte percentage of white cells; LIHC cis rs801193 1.000 rs2707854 chr7:66212597 G/A cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.5e-9 Aortic root size; LIHC cis rs929354 0.772 rs2023975 chr7:157012096 G/A cg05182265 chr7:156933206 UBE3C -0.33 -6.28 -0.32 1.01e-9 Body mass index; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg08677398 chr8:58056175 NA 0.4 6.02 0.31 4.61e-9 Developmental language disorder (linguistic errors); LIHC cis rs3823572 0.504 rs2971977 chr7:133648347 C/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.85 -0.3 1.18e-8 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.872 rs1570318 chr6:160111473 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.76 0.43 9.46e-17 Age-related macular degeneration (geographic atrophy); LIHC trans rs916888 0.821 rs199509 chr17:44858728 G/A cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs3806843 0.706 rs2563302 chr5:140079051 T/C cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg16145915 chr7:1198662 ZFAND2A -0.4 -10.11 -0.48 3.34e-21 Longevity;Endometriosis; LIHC cis rs7914558 0.966 rs11191471 chr10:104702050 T/A cg15744005 chr10:104629667 AS3MT -0.4 -9.11 -0.44 7.24e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1577917 0.771 rs7452605 chr6:86240951 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 12.0 0.54 6.38e-28 Response to antipsychotic treatment; LIHC cis rs3820500 0.543 rs1289820 chr1:117921039 T/G cg20383390 chr1:117909022 MAN1A2 0.44 5.75 0.3 1.93e-8 Pneumonia; LIHC cis rs3809566 1.000 rs4774471 chr15:63332645 A/T cg12160578 chr15:63334699 TPM1 0.6 8.58 0.42 3.46e-16 Platelet count; LIHC cis rs2816062 0.786 rs742486 chr1:18900829 G/A cg18795169 chr1:18902165 NA -0.79 -17.59 -0.69 8.57e-50 Urate levels in lean individuals; LIHC cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg11764359 chr7:65958608 NA -0.59 -6.13 -0.31 2.49e-9 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg00091569 chr3:40428383 ENTPD3 0.4 6.79 0.34 4.86e-11 Renal cell carcinoma; LIHC cis rs965469 1.000 rs6051705 chr20:3253143 G/A cg25506879 chr20:3388711 C20orf194 -0.58 -6.99 -0.35 1.44e-11 IFN-related cytopenia; LIHC cis rs7552404 0.731 rs10732723 chr1:76392437 C/T cg03433033 chr1:76189801 ACADM -0.53 -6.48 -0.33 3.2e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs921968 0.565 rs7562426 chr2:219605118 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.9e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6879260 1.000 rs1035411 chr5:179729519 A/G cg13944838 chr5:179740914 GFPT2 -0.5 -6.71 -0.34 8.04e-11 Height; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.49 0.62 2.02e-37 Prudent dietary pattern; LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg07424592 chr7:64974309 NA 0.44 6.75 0.34 6.28e-11 Calcium levels; LIHC cis rs67478160 0.572 rs8016014 chr14:104293798 G/C cg08213375 chr14:104286397 PPP1R13B 0.64 12.12 0.55 2.29e-28 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg23228418 chr1:151119228 SEMA6C 0.58 7.76 0.39 9.67e-14 Hepatitis; LIHC cis rs2153535 0.580 rs6918391 chr6:8461178 A/C cg21535247 chr6:8435926 SLC35B3 0.63 8.26 0.41 3.22e-15 Motion sickness; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg00091569 chr3:40428383 ENTPD3 0.35 6.05 0.31 3.74e-9 Renal cell carcinoma; LIHC cis rs1670533 0.932 rs935968 chr4:1063187 G/T cg27284194 chr4:1044797 NA 0.59 8.88 0.43 3.95e-17 Recombination rate (females); LIHC cis rs11098699 0.821 rs4833887 chr4:124208033 T/C cg09941581 chr4:124220074 SPATA5 0.33 6.52 0.33 2.57e-10 Mosquito bite size; LIHC cis rs939574 0.790 rs79225383 chr2:220093972 C/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.88 6.37 0.33 6.01e-10 Platelet distribution width; LIHC cis rs9393692 0.905 rs9379843 chr6:26289435 A/G cg00631329 chr6:26305371 NA -0.42 -7.12 -0.36 6.42e-12 Educational attainment; LIHC cis rs12048904 0.964 rs12027668 chr1:101330984 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 7.96 0.4 2.52e-14 Multiple sclerosis; LIHC cis rs1865760 0.892 rs9379806 chr6:25940958 G/A cg03264133 chr6:25882463 NA -0.42 -6.26 -0.32 1.17e-9 Height; LIHC cis rs4803468 1.000 rs284655 chr19:41928765 C/T cg14132834 chr19:41945861 ATP5SL -0.46 -6.79 -0.34 4.91e-11 Height; LIHC cis rs765787 0.530 rs2554455 chr15:45521304 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.5 -0.38 5.55e-13 Uric acid levels; LIHC cis rs797680 0.856 rs11164876 chr1:93630510 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.35 -6.13 -0.31 2.46e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg26668828 chr6:292823 DUSP22 -0.52 -7.28 -0.37 2.31e-12 Menopause (age at onset); LIHC cis rs9291683 0.588 rs3733586 chr4:9997534 C/T cg11266682 chr4:10021025 SLC2A9 0.3 6.3 0.32 9.1e-10 Bone mineral density; LIHC cis rs4845570 0.920 rs11810571 chr1:151762308 C/G cg07092448 chr1:151763213 TDRKH 1.0 18.52 0.71 1.54e-53 Coronary artery disease; LIHC cis rs244293 0.637 rs6504945 chr17:52999956 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.48 -6.94 -0.35 2.02e-11 Menarche (age at onset); LIHC cis rs614226 0.872 rs12307148 chr12:120903179 T/C cg01236616 chr12:121019343 POP5 -1.19 -18.27 -0.7 1.61e-52 Type 1 diabetes nephropathy; LIHC cis rs9309473 0.948 rs10173534 chr2:73813432 C/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.63 -0.34 1.34e-10 Metabolite levels; LIHC cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.95 0.31 6.79e-9 Electroencephalogram traits; LIHC cis rs3816788 0.620 rs11783414 chr8:21773384 A/G cg17168535 chr8:21777572 XPO7 -0.53 -9.49 -0.46 4.23e-19 Lung cancer in ever smokers; LIHC cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg06481639 chr22:41940642 POLR3H 0.72 7.52 0.38 4.86e-13 Vitiligo; LIHC cis rs11676348 0.772 rs6738953 chr2:218950036 C/A cg00012203 chr2:219082015 ARPC2 -0.44 -5.88 -0.3 9.98e-9 Ulcerative colitis; LIHC cis rs9303401 0.659 rs12150536 chr17:56640834 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.71 0.43 1.36e-16 Cognitive test performance; LIHC cis rs6912958 1.000 rs13214153 chr6:88153983 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.22 -0.36 3.41e-12 Monocyte percentage of white cells; LIHC cis rs7927771 1.000 rs1317149 chr11:47486885 C/T cg18512352 chr11:47633146 NA -0.26 -6.2 -0.32 1.58e-9 Subjective well-being; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24051152 chr8:145133159 EXOSC4 0.4 6.06 0.31 3.59e-9 Cognitive function; LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg21724239 chr8:58056113 NA -0.68 -8.07 -0.4 1.19e-14 Developmental language disorder (linguistic errors); LIHC cis rs11785400 1.000 rs3824208 chr8:143743653 C/G cg24634471 chr8:143751801 JRK 0.51 8.23 0.41 4.08e-15 Schizophrenia; LIHC cis rs611744 0.967 rs594405 chr8:109193607 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs1814175 0.645 rs7395438 chr11:49877379 G/T cg18944383 chr4:111397179 ENPEP 0.27 6.95 0.35 1.82e-11 Height; LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg04013166 chr16:89971882 TCF25 0.6 7.85 0.39 5.58e-14 Skin colour saturation; LIHC cis rs12291225 0.535 rs16930126 chr11:14404983 C/T cg19336497 chr11:14380999 RRAS2 0.54 10.31 0.49 6.89e-22 Sense of smell; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg02993280 chr1:107599747 PRMT6 -0.7 -11.29 -0.52 2.49e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12586317 0.547 rs60152856 chr14:35421373 G/A cg05294307 chr14:35346193 BAZ1A -0.53 -7.87 -0.39 4.63e-14 Psoriasis; LIHC cis rs8141529 0.732 rs2269577 chr22:29196757 G/C cg15103426 chr22:29168792 CCDC117 0.67 11.68 0.53 9.38e-27 Lymphocyte counts; LIHC cis rs6840360 0.967 rs6535812 chr4:152599374 C/A cg22705602 chr4:152727874 NA -0.31 -6.53 -0.33 2.38e-10 Intelligence (multi-trait analysis); LIHC cis rs79387448 0.745 rs1523196 chr2:103163700 T/G cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC trans rs7618501 1.000 rs60205400 chr3:49800272 C/T cg21582582 chr3:182698605 DCUN1D1 0.52 6.87 0.35 3.02e-11 Intelligence (multi-trait analysis); LIHC cis rs4988958 0.565 rs10206291 chr2:103038863 T/C cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma (childhood onset); LIHC cis rs8180040 0.871 rs11716661 chr3:47517773 G/T cg27129171 chr3:47204927 SETD2 -0.57 -9.75 -0.47 5.67e-20 Colorectal cancer; LIHC cis rs1008375 0.800 rs62296338 chr4:17613425 G/T cg15017067 chr4:17643749 FAM184B 0.33 5.74 0.3 2.1e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2243480 1.000 rs1392104 chr7:65759107 G/A cg10756647 chr7:56101905 PSPH -1.03 -12.48 -0.56 1.05e-29 Diabetic kidney disease; LIHC cis rs920590 0.679 rs4577973 chr8:19658017 A/G cg01411142 chr8:19674711 INTS10 0.43 6.5 0.33 2.76e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs1005277 0.579 rs176838 chr10:38371899 A/T cg00409905 chr10:38381863 ZNF37A 0.6 10.53 0.49 1.17e-22 Extrinsic epigenetic age acceleration; LIHC cis rs4665809 1.000 rs2053367 chr2:26293413 T/C cg04944784 chr2:26401820 FAM59B -0.68 -8.65 -0.42 2.01e-16 Gut microbiome composition (summer); LIHC cis rs4423214 0.625 rs78685409 chr11:71137383 T/C cg05163923 chr11:71159392 DHCR7 -0.64 -8.71 -0.43 1.28e-16 Vitamin D levels; LIHC cis rs79387448 0.655 rs17639215 chr2:102953444 G/A cg09003973 chr2:102972529 NA 1.14 9.17 0.44 4.47e-18 Gut microbiota (bacterial taxa); LIHC trans rs8073060 0.544 rs7210966 chr17:33986334 G/C cg19694781 chr19:47549865 TMEM160 -1.27 -13.85 -0.6 6.39e-35 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs3135071 1.000 rs3135071 chr4:2406321 C/T cg01601518 chr4:2404284 ZFYVE28 0.64 7.3 0.37 2.1e-12 Influenza A (H1N1) severity; LIHC cis rs9905704 0.624 rs8080071 chr17:57093825 C/T cg05425664 chr17:57184151 TRIM37 0.42 6.04 0.31 4.13e-9 Testicular germ cell tumor; LIHC cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg10802521 chr3:52805072 NEK4 -0.46 -7.77 -0.39 9.08e-14 Bipolar disorder; LIHC cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.72 0.39 1.29e-13 Electroencephalogram traits; LIHC cis rs2180341 0.961 rs7774468 chr6:127592501 G/C cg27446573 chr6:127587934 RNF146 1.01 15.28 0.64 1.49e-40 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08535374 chr1:110679730 NA 0.51 7.06 0.36 9.17e-12 Pancreatic cancer; LIHC cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 10.28 0.49 8.93e-22 Platelet count; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg04024499 chr13:25860865 MTMR6 0.46 7.58 0.38 3.37e-13 Calcium levels; LIHC cis rs6466055 0.720 rs4730072 chr7:104832260 A/T cg04380332 chr7:105027541 SRPK2 -0.35 -6.64 -0.34 1.24e-10 Schizophrenia; LIHC cis rs57502260 0.704 rs923346 chr11:68182375 T/C cg01657329 chr11:68192670 LRP5 -0.59 -6.66 -0.34 1.1e-10 Total body bone mineral density (age 45-60); LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg09033563 chr22:24373618 LOC391322 -0.52 -7.06 -0.36 9.29e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7264396 0.580 rs6060648 chr20:34456704 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -7.93 -0.39 3.05e-14 Total cholesterol levels; LIHC cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg21724239 chr8:58056113 NA 0.57 6.31 0.32 8.56e-10 Developmental language disorder (linguistic errors); LIHC cis rs644799 1.000 rs586498 chr11:95537828 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg03517284 chr6:25882590 NA -0.46 -7.16 -0.36 5.12e-12 Height; LIHC trans rs11165623 0.543 rs6656866 chr1:97002238 T/C cg10631902 chr5:14652156 NA -0.29 -6.62 -0.34 1.36e-10 Hip circumference;Waist circumference; LIHC cis rs1059312 1.000 rs3825180 chr12:129279242 A/G cg21616243 chr12:129299702 MGC16384;SLC15A4 0.71 14.23 0.61 2.12e-36 Systemic lupus erythematosus; LIHC cis rs7961581 0.763 rs7306184 chr12:71618203 C/T cg05756094 chr12:71608604 NA 0.36 5.82 0.3 1.33e-8 Type 2 diabetes; LIHC cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg10802521 chr3:52805072 NEK4 -0.46 -7.73 -0.39 1.2e-13 Electroencephalogram traits; LIHC cis rs9309473 1.000 rs7585004 chr2:73666645 C/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.99 -0.35 1.43e-11 Metabolite levels; LIHC cis rs9303280 0.806 rs62067034 chr17:38063738 C/T cg11212589 chr17:38028394 ZPBP2 0.36 7.32 0.37 1.73e-12 Self-reported allergy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00297767 chr21:40721426 HMGN1 0.46 6.47 0.33 3.4e-10 Lung function (FEV1/FVC); LIHC cis rs875971 0.895 rs7782806 chr7:65657897 C/T cg18252515 chr7:66147081 NA 0.42 5.77 0.3 1.79e-8 Aortic root size; LIHC cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg08499158 chr17:42289980 UBTF 0.51 8.67 0.42 1.81e-16 Total body bone mineral density; LIHC cis rs11971779 0.680 rs1862879 chr7:139019951 A/G cg07862535 chr7:139043722 LUC7L2 0.58 10.01 0.48 7.3e-21 Diisocyanate-induced asthma; LIHC cis rs76419734 0.510 rs2193856 chr4:106742958 A/C cg24545054 chr4:106630052 GSTCD;INTS12 -0.71 -7.3 -0.37 2.1e-12 Post bronchodilator FEV1; LIHC cis rs4423214 1.000 rs28364617 chr11:71159764 T/G cg05163923 chr11:71159392 DHCR7 0.97 15.12 0.63 6.35e-40 Vitamin D levels; LIHC cis rs3761847 0.593 rs10985140 chr9:123822837 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.42 5.87 0.3 1.05e-8 Rheumatoid arthritis; LIHC cis rs2370759 1.000 rs79442609 chr10:32608749 C/T cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs4969178 0.600 rs4969184 chr17:76393413 G/A cg02836325 chr17:76403955 PGS1 0.34 6.67 0.34 1.04e-10 HDL cholesterol levels; LIHC trans rs11098499 0.738 rs34965784 chr4:120361586 G/C cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs7772486 0.875 rs2224120 chr6:146343280 A/C cg23711669 chr6:146136114 FBXO30 0.67 11.83 0.54 2.59e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs7582180 0.663 rs930374 chr2:100962700 A/G cg14675211 chr2:100938903 LONRF2 0.54 8.06 0.4 1.27e-14 Intelligence (multi-trait analysis); LIHC cis rs2303759 0.709 rs7256363 chr19:49827804 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.53 7.89 0.39 4.02e-14 Multiple sclerosis; LIHC cis rs2204008 0.811 rs12368410 chr12:38305705 C/T cg26384229 chr12:38710491 ALG10B 0.83 10.34 0.49 5.4e-22 Bladder cancer; LIHC cis rs5769765 0.955 rs1321 chr22:50297435 A/G cg02269571 chr22:50332266 NA -0.63 -8.95 -0.44 2.24e-17 Schizophrenia; LIHC cis rs3903072 0.652 rs501630 chr11:65637273 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.49 -7.22 -0.36 3.5e-12 Breast cancer; LIHC cis rs9399135 0.844 rs13209789 chr6:135367916 A/G cg22676075 chr6:135203613 NA 0.41 6.59 0.34 1.66e-10 Red blood cell count; LIHC cis rs17253792 0.822 rs17746106 chr14:56069168 C/T cg01858014 chr14:56050164 KTN1 -0.73 -8.23 -0.41 3.93e-15 Putamen volume; LIHC cis rs34172651 0.502 rs12930727 chr16:24838497 G/T cg00339695 chr16:24857497 SLC5A11 -0.36 -6.38 -0.33 5.77e-10 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 5.98e-9 Menopause (age at onset); LIHC cis rs7212590 0.581 rs28539312 chr17:57834602 A/C cg10252138 chr17:58120427 NA -0.59 -5.91 -0.3 8.3e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg25072359 chr17:41440525 NA 0.38 6.06 0.31 3.55e-9 Menopause (age at onset); LIHC cis rs7914558 1.000 rs7081075 chr10:104929191 C/T cg15744005 chr10:104629667 AS3MT -0.39 -8.88 -0.43 3.84e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10464366 0.544 rs4540324 chr7:39185299 G/C cg20302533 chr7:39170763 POU6F2 0.38 7.02 0.35 1.22e-11 IgG glycosylation; LIHC cis rs12048904 1.000 rs12048904 chr1:101331536 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.46 -7.87 -0.39 4.75e-14 Multiple sclerosis; LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg18279126 chr7:2041391 MAD1L1 0.4 6.74 0.34 6.58e-11 Bipolar disorder and schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03468541 chr14:89029199 ZC3H14 0.59 7.81 0.39 6.98e-14 Lung function (FEV1/FVC); LIHC cis rs765787 0.530 rs28526629 chr15:45540462 C/T cg25801113 chr15:45476975 SHF 0.39 6.62 0.34 1.41e-10 Uric acid levels; LIHC cis rs7546668 1.000 rs6686966 chr1:15835472 C/T cg11706911 chr1:15910989 AGMAT 0.45 6.91 0.35 2.41e-11 Glomerular filtration rate (creatinine); LIHC cis rs4409675 0.576 rs1474908 chr1:28213213 C/T cg23691781 chr1:28212827 C1orf38 -0.33 -7.82 -0.39 6.53e-14 Corneal astigmatism; LIHC cis rs7772486 0.817 rs2748491 chr6:146327759 T/C cg23711669 chr6:146136114 FBXO30 0.66 11.38 0.52 1.2e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs10793273 1 rs10793273 chr11:77742595 T/C cg09721595 chr11:77773924 THRSP -0.53 -9.14 -0.44 5.78e-18 Pelvic organ prolapse; LIHC cis rs1163251 0.902 rs514491 chr1:120216743 C/T cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02668984 chr17:48172022 PDK2 0.39 6.51 0.33 2.76e-10 Cognitive function; LIHC cis rs7635838 0.686 rs347588 chr3:11287504 C/T cg00170343 chr3:11313890 ATG7 0.54 8.13 0.4 8.11e-15 HDL cholesterol; LIHC cis rs4684776 0.935 rs35166981 chr3:11385356 G/T cg00170343 chr3:11313890 ATG7 -0.49 -6.57 -0.33 1.85e-10 Small vessel stroke; LIHC cis rs875971 0.964 rs6945019 chr7:65922458 C/G cg18876405 chr7:65276391 NA 0.39 6.96 0.35 1.71e-11 Aortic root size; LIHC cis rs10744422 1.000 rs2135014 chr12:123333065 C/T cg22842854 chr12:123319900 HIP1R -0.74 -9.76 -0.47 5.03e-20 Schizophrenia; LIHC cis rs34172651 0.517 rs12920774 chr16:24830750 T/C cg00152838 chr16:24741724 TNRC6A -0.52 -6.02 -0.31 4.48e-9 Intelligence (multi-trait analysis); LIHC cis rs7551222 0.716 rs7541589 chr1:204542521 G/A cg20240347 chr1:204465584 NA -0.36 -7.42 -0.37 9.17e-13 Schizophrenia; LIHC cis rs13064411 0.696 rs6786974 chr3:113190149 T/A cg18753928 chr3:113234510 CCDC52 -0.44 -6.0 -0.31 5.12e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs6426558 0.537 rs2102634 chr1:227324308 T/C cg10327440 chr1:227177885 CDC42BPA -0.45 -6.95 -0.35 1.81e-11 Neutrophil percentage of white cells; LIHC cis rs11122272 0.735 rs2739515 chr1:231514681 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs5770917 1.000 rs3213445 chr22:51015838 T/C cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.52 -6.95 -0.35 1.84e-11 Narcolepsy; LIHC cis rs9611565 0.592 rs12484254 chr22:41962003 T/A cg03806693 chr22:41940476 POLR3H -0.82 -9.1 -0.44 7.86e-18 Vitiligo; LIHC cis rs3796352 0.667 rs11720228 chr3:52877270 G/A cg04865290 chr3:52927548 TMEM110 -0.46 -6.2 -0.32 1.66e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg24545908 chr18:68097886 NA 0.41 7.21 0.36 3.68e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs11190604 1.000 rs2489036 chr10:102319581 A/G cg07080220 chr10:102295463 HIF1AN 0.52 7.2 0.36 3.78e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs1005277 0.579 rs9299760 chr10:38377920 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg06873352 chr17:61820015 STRADA 0.6 9.31 0.45 1.55e-18 Height; LIHC cis rs116095464 0.558 rs2162870 chr5:228129 G/A cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs4780401 0.609 rs7205994 chr16:11815964 C/T cg01061890 chr16:11836724 TXNDC11 -0.65 -10.39 -0.49 3.73e-22 Rheumatoid arthritis; LIHC cis rs12744310 1.000 rs12035012 chr1:41750648 C/A cg03962019 chr1:41807865 NA 0.38 6.19 0.32 1.73e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1215050 0.740 rs1214994 chr4:99035577 C/T cg05340658 chr4:99064831 C4orf37 0.4 6.25 0.32 1.21e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1552244 0.882 rs67762674 chr3:10014485 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.71 0.5 2.81e-23 Alzheimer's disease; LIHC cis rs2412488 0.853 rs6818788 chr4:54356173 C/T cg22241045 chr4:54363911 LNX1 0.42 6.72 0.34 7.65e-11 DNA methylation (variation); LIHC cis rs6088580 0.634 rs6579165 chr20:32994715 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs7560272 0.723 rs7585119 chr2:73724679 A/T cg20560298 chr2:73613845 ALMS1 -0.36 -5.79 -0.3 1.55e-8 Schizophrenia; LIHC cis rs7249142 0.549 rs2238667 chr19:19282523 G/A cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.42 -6.96 -0.35 1.72e-11 IgG glycosylation; LIHC cis rs7572733 0.534 rs1518365 chr2:198809410 T/C cg03934865 chr2:198174659 NA 0.48 7.02 0.35 1.23e-11 Dermatomyositis; LIHC cis rs875971 0.862 rs801203 chr7:66023012 A/G cg18252515 chr7:66147081 NA 0.45 6.59 0.34 1.62e-10 Aortic root size; LIHC cis rs2637266 0.967 rs12246436 chr10:78352914 C/T cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs9917256 0.748 rs1955337 chr2:169129145 G/T cg07857142 chr2:169103971 STK39 0.52 5.78 0.3 1.7e-8 Parkinson's disease; LIHC cis rs801193 0.548 rs2659891 chr7:66201114 A/G cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.34e-11 Aortic root size; LIHC cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.17e-11 Alzheimer's disease; LIHC cis rs12042938 0.507 rs2570408 chr1:231732934 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.51 -7.03 -0.36 1.13e-11 Neuranatomic and neurocognitive phenotypes; LIHC cis rs4803468 1.000 rs10417997 chr19:41902361 G/A cg14132834 chr19:41945861 ATP5SL -0.43 -6.5 -0.33 2.81e-10 Height; LIHC trans rs7246657 0.943 rs10415937 chr19:37830064 T/G cg24637308 chr11:6592297 DNHD1 0.43 6.1 0.31 2.94e-9 Coronary artery calcification; LIHC cis rs801193 0.967 rs2707853 chr7:66214010 G/A cg18876405 chr7:65276391 NA 0.43 7.37 0.37 1.26e-12 Aortic root size; LIHC cis rs11671005 0.571 rs56243535 chr19:59006150 C/T cg25952890 chr19:58913133 NA 0.66 6.68 0.34 9.8e-11 Mean platelet volume; LIHC cis rs992157 0.835 rs12987180 chr2:219144089 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.12 -0.55 2.19e-28 Colorectal cancer; LIHC cis rs2292864 0.764 rs3785872 chr17:45372075 G/A cg18085866 chr17:45331354 ITGB3 -0.67 -7.02 -0.35 1.22e-11 Left atrial antero-posterior diameter; LIHC cis rs12188164 0.561 rs2251843 chr5:457955 C/T cg26072250 chr5:443457 EXOC3;C5orf55 -0.47 -7.03 -0.36 1.16e-11 Cystic fibrosis severity; LIHC cis rs2302190 0.882 rs6503869 chr17:56637461 C/G cg05425664 chr17:57184151 TRIM37 -0.46 -5.79 -0.3 1.58e-8 Vitamin D levels; LIHC cis rs10193935 0.901 rs222468 chr2:42642531 C/T cg27598129 chr2:42591480 NA -0.7 -10.65 -0.5 4.59e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg21782813 chr7:2030301 MAD1L1 0.42 7.47 0.37 6.95e-13 Bipolar disorder and schizophrenia; LIHC trans rs8073060 0.586 rs225264 chr17:33961335 A/G cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6942756 1.000 rs6942756 chr7:128886821 T/G cg02491457 chr7:128862824 NA -0.72 -11.37 -0.52 1.31e-25 White matter hyperintensity burden; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg14913676 chr19:46234055 FBXO46 -0.48 -6.16 -0.32 2.02e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs10089 1.000 rs3805606 chr5:127470813 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.54 -6.65 -0.34 1.19e-10 Ileal carcinoids; LIHC cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg13607699 chr17:42295918 UBTF 0.44 7.01 0.35 1.26e-11 Total body bone mineral density; LIHC cis rs6840360 0.571 rs28608620 chr4:152504791 C/T cg22705602 chr4:152727874 NA -0.32 -6.23 -0.32 1.38e-9 Intelligence (multi-trait analysis); LIHC cis rs66887589 0.967 rs3775842 chr4:120427732 G/A cg09307838 chr4:120376055 NA 0.5 7.66 0.38 1.95e-13 Diastolic blood pressure; LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg07677032 chr17:61819896 STRADA 0.41 6.09 0.31 3.04e-9 Prudent dietary pattern; LIHC cis rs11871801 0.517 rs35635959 chr17:40772288 T/C cg14558262 chr17:40713999 COASY 0.62 9.41 0.45 7.34e-19 Crohn's disease; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.15 0.4 7.16e-15 Height; LIHC cis rs3806843 0.932 rs2563269 chr5:140136468 G/T cg26395211 chr5:140044315 WDR55 0.41 6.13 0.31 2.42e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7309 0.935 rs11884495 chr2:162059969 A/T cg22496339 chr2:162101262 NA 0.81 13.56 0.59 7.91e-34 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs2637266 0.935 rs4353214 chr10:78393149 C/T cg18941641 chr10:78392320 NA -0.29 -6.39 -0.33 5.28e-10 Pulmonary function; LIHC cis rs782590 0.807 rs782572 chr2:55912120 T/C cg03859395 chr2:55845619 SMEK2 0.82 14.0 0.6 1.62e-35 Metabolic syndrome; LIHC cis rs11628318 0.614 rs1190338 chr14:103105792 T/G cg01864069 chr14:103024347 NA -0.46 -7.35 -0.37 1.5e-12 Platelet count; LIHC cis rs1865721 0.771 rs727893 chr18:73136931 G/A cg26385618 chr18:73139727 C18orf62 -0.32 -8.64 -0.42 2.13e-16 Intelligence; LIHC cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs8067545 0.641 rs203450 chr17:19823070 C/T cg13482628 chr17:19912719 NA 0.39 6.37 0.33 6.02e-10 Schizophrenia; LIHC trans rs8002861 0.935 rs1822969 chr13:44418164 G/A cg17145862 chr1:211918768 LPGAT1 0.58 10.78 0.5 1.54e-23 Leprosy; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg21930229 chr1:32758033 HDAC1 0.42 6.45 0.33 3.84e-10 Metabolic traits; LIHC cis rs937213 0.573 rs2412464 chr15:40303842 G/A cg01081584 chr15:40268610 EIF2AK4 -0.37 -6.28 -0.32 1.03e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg21877656 chr19:58662188 ZNF329 1.08 8.49 0.42 6.2e-16 Cholesterol, total; LIHC cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg12310025 chr6:25882481 NA -0.64 -9.01 -0.44 1.54e-17 Blood metabolite levels; LIHC trans rs1814175 0.527 rs7128827 chr11:49665644 C/T cg15704280 chr7:45808275 SEPT13 0.8 11.84 0.54 2.41e-27 Height; LIHC cis rs8060686 0.516 rs9939821 chr16:68167787 T/A cg05110241 chr16:68378359 PRMT7 -0.53 -6.26 -0.32 1.15e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs7618501 0.601 rs2624825 chr3:50154989 G/A cg24110177 chr3:50126178 RBM5 0.51 8.24 0.41 3.74e-15 Intelligence (multi-trait analysis); LIHC cis rs2073300 1.000 rs6106656 chr20:23444301 A/G cg12062639 chr20:23401060 NAPB 0.85 10.27 0.49 9.25e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11626933 1.000 rs2236402 chr14:90734378 C/G cg07150772 chr14:90864620 CALM1 -0.42 -6.02 -0.31 4.5e-9 Gut microbiota (bacterial taxa); LIHC cis rs2645694 0.626 rs2645684 chr4:77819892 A/C cg03477792 chr4:77819574 ANKRD56 0.59 8.68 0.42 1.64e-16 Emphysema distribution in smoking; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg06656553 chr16:89960601 TCF25 -0.46 -5.86 -0.3 1.12e-8 Skin colour saturation; LIHC cis rs2180341 1.000 rs6569482 chr6:127631371 C/T cg27446573 chr6:127587934 RNF146 1.03 16.06 0.66 1.17e-43 Breast cancer; LIHC cis rs7772486 0.790 rs2247666 chr6:146220409 C/A cg05347473 chr6:146136440 FBXO30 0.38 6.05 0.31 3.73e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2072499 0.966 rs6427307 chr1:156190083 A/G cg25208724 chr1:156163844 SLC25A44 0.92 15.85 0.65 8.21e-43 Testicular germ cell tumor; LIHC cis rs854765 0.647 rs854790 chr17:18028318 C/G cg04398451 chr17:18023971 MYO15A -0.64 -10.79 -0.5 1.48e-23 Total body bone mineral density; LIHC cis rs11098499 0.954 rs6846442 chr4:120326323 G/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs7666738 0.546 rs10007424 chr4:98885450 C/T cg05340658 chr4:99064831 C4orf37 0.53 6.96 0.35 1.7e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs2289583 0.642 rs11635266 chr15:75386649 T/C cg15902774 chr15:75289873 SCAMP5 0.33 5.95 0.31 6.79e-9 Systemic lupus erythematosus; LIHC cis rs11098699 0.784 rs7684146 chr4:124207309 C/A cg09941581 chr4:124220074 SPATA5 0.32 6.38 0.33 5.62e-10 Mosquito bite size; LIHC cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg18357526 chr6:26021779 HIST1H4A 0.67 8.52 0.42 5.34e-16 Uric acid levels; LIHC cis rs9814567 1.000 rs4955485 chr3:134295843 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.41 -0.56 1.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs36051895 0.632 rs10118930 chr9:5148278 C/T cg02405213 chr9:5042618 JAK2 -0.68 -12.23 -0.55 8.93e-29 Pediatric autoimmune diseases; LIHC cis rs244731 0.920 rs244707 chr5:176555636 A/T cg16006841 chr5:176797999 RGS14 0.61 5.89 0.3 9.18e-9 Urate levels in lean individuals; LIHC cis rs7614311 0.681 rs6809100 chr3:63901180 A/G cg22134162 chr3:63841271 THOC7 -0.53 -6.06 -0.31 3.62e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.59 0.38 3.07e-13 Bipolar disorder; LIHC cis rs2153535 0.580 rs1414346 chr6:8471574 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04787407 chr4:99916511 METAP1 0.42 6.82 0.35 4.06e-11 Cognitive function; LIHC cis rs600806 0.778 rs6693932 chr1:110003575 T/C cg10127483 chr1:110009974 SYPL2 0.49 5.99 0.31 5.43e-9 Intelligence (multi-trait analysis); LIHC cis rs17401966 0.867 rs7546364 chr1:10418815 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.87 -0.35 3.06e-11 Hepatocellular carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05570707 chr2:24270316 C2orf44 0.48 6.7 0.34 8.61e-11 Lung function (FEV1/FVC); LIHC cis rs2842992 0.692 rs1128661 chr6:160211554 T/G cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs6912958 1.000 rs9294379 chr6:88152535 C/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.4 -7.04 -0.36 1.04e-11 Monocyte percentage of white cells; LIHC cis rs3741404 0.609 rs651855 chr11:63870810 T/C cg05016508 chr11:63871570 FLRT1;MACROD1 0.42 6.69 0.34 9.1e-11 Platelet count; LIHC trans rs6489882 0.867 rs4766664 chr12:113362997 T/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6.08e-10 Chronic lymphocytic leukemia; LIHC cis rs116095464 0.558 rs61689490 chr5:224904 T/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs2274273 0.682 rs8008134 chr14:55507520 T/C cg01864836 chr14:55583639 NA -0.35 -6.02 -0.31 4.62e-9 Protein biomarker; LIHC cis rs8060686 0.641 rs3743735 chr16:68119555 G/A cg09835421 chr16:68378352 PRMT7 -0.5 -5.92 -0.3 7.91e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs7249142 0.512 rs12981160 chr19:19298099 T/A cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.4 -6.64 -0.34 1.26e-10 IgG glycosylation; LIHC cis rs1983891 0.955 rs4714487 chr6:41547312 T/C cg20194872 chr6:41519635 FOXP4 0.4 6.43 0.33 4.26e-10 Prostate cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01086369 chr19:50885373 NR1H2 0.45 6.77 0.34 5.53e-11 Longevity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21565415 chr11:618993 MUPCDH -0.44 -6.42 -0.33 4.62e-10 Lung function (FEV1/FVC); LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.579 rs2008449 chr10:38414204 A/T cg25427524 chr10:38739819 LOC399744 0.68 13.35 0.59 5.14e-33 Extrinsic epigenetic age acceleration; LIHC cis rs55665837 1.000 rs34382046 chr11:14451318 C/T cg19336497 chr11:14380999 RRAS2 -0.44 -8.12 -0.4 8.51e-15 Vitamin D levels; LIHC cis rs9393692 0.967 rs6456712 chr6:26302573 A/C cg13736514 chr6:26305472 NA -0.42 -6.56 -0.33 2.01e-10 Educational attainment; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.94 0.44 2.39e-17 Platelet count; LIHC cis rs9911578 1.000 rs8071280 chr17:57010225 T/C cg12560992 chr17:57184187 TRIM37 0.97 17.45 0.69 3.29e-49 Intelligence (multi-trait analysis); LIHC cis rs77861329 1.000 rs17051977 chr3:52182944 A/G cg08692210 chr3:52188851 WDR51A 0.83 8.12 0.4 8.62e-15 Macrophage inflammatory protein 1b levels; LIHC cis rs28374715 0.662 rs10851403 chr15:41466087 T/G cg18705301 chr15:41695430 NDUFAF1 -0.83 -9.24 -0.45 2.64e-18 Ulcerative colitis; LIHC cis rs769267 0.930 rs751856 chr19:19602945 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.88 0.39 4.52e-14 Tonsillectomy; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs10791097 0.694 rs3190331 chr11:130748131 C/T cg12179176 chr11:130786555 SNX19 -0.79 -12.81 -0.57 5.78e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11577318 0.853 rs12743998 chr1:26629882 G/A cg18121669 chr1:26560928 CCDC21 0.5 8.0 0.4 1.91e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg03517284 chr6:25882590 NA -0.63 -8.86 -0.43 4.45e-17 Blood metabolite levels; LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg00091569 chr3:40428383 ENTPD3 -0.39 -6.59 -0.34 1.62e-10 Renal cell carcinoma; LIHC trans rs2832077 0.943 rs11702320 chr21:30195251 A/T cg14791747 chr16:20752902 THUMPD1 0.47 6.29 0.32 9.64e-10 Cognitive test performance; LIHC cis rs9473924 0.542 rs9473946 chr6:50892950 G/A cg14470998 chr6:50812995 TFAP2B 0.91 10.53 0.49 1.22e-22 Body mass index; LIHC trans rs35110281 0.627 rs1595167 chr21:44965874 T/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.49 6.74 0.34 6.68e-11 Mean corpuscular volume; LIHC cis rs8017423 0.904 rs2149647 chr14:90769539 C/T cg14092571 chr14:90743983 NA 0.44 6.76 0.34 5.93e-11 Mortality in heart failure; LIHC cis rs1451375 0.583 rs3807555 chr7:50610569 A/G cg14593290 chr7:50529359 DDC 0.62 9.75 0.47 5.55e-20 Malaria; LIHC cis rs10242455 0.571 rs11734 chr7:99229768 C/G cg25640893 chr7:99214727 ZNF498 -0.85 -6.05 -0.31 3.87e-9 Blood metabolite levels; LIHC cis rs10779751 0.610 rs2486921 chr1:11124943 G/A cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs2479724 0.840 rs6925777 chr6:41750822 C/T cg17623882 chr6:41773611 USP49 0.56 8.83 0.43 5.37e-17 Menarche (age at onset); LIHC cis rs7589728 0.925 rs80065975 chr2:88502758 G/A cg14558114 chr2:88469736 THNSL2 0.6 5.72 0.3 2.35e-8 Plasma clusterin levels; LIHC cis rs17401966 0.838 rs11580854 chr1:10293565 G/A cg19773385 chr1:10388646 KIF1B -0.39 -7.09 -0.36 7.68e-12 Hepatocellular carcinoma; LIHC cis rs8180040 0.726 rs7625070 chr3:47095518 A/G cg16586182 chr3:47516702 SCAP -0.52 -9.47 -0.46 4.91e-19 Colorectal cancer; LIHC cis rs7927592 0.871 rs871212 chr11:68348695 T/A cg01657329 chr11:68192670 LRP5 -0.48 -6.35 -0.32 6.77e-10 Total body bone mineral density; LIHC cis rs3749237 0.595 rs4955412 chr3:49418168 A/C cg07636037 chr3:49044803 WDR6 0.5 7.53 0.38 4.44e-13 Resting heart rate; LIHC cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg27094323 chr7:1216898 NA -0.4 -5.71 -0.3 2.41e-8 Longevity;Endometriosis; LIHC cis rs7772486 0.790 rs1832362 chr6:146179955 C/T cg05347473 chr6:146136440 FBXO30 0.35 5.86 0.3 1.09e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs7246657 0.943 rs7257672 chr19:37823859 G/C cg24637308 chr11:6592297 DNHD1 0.44 6.17 0.32 1.98e-9 Coronary artery calcification; LIHC trans rs11088226 0.846 rs2154501 chr21:33926451 G/A cg09050820 chr6:167586206 TCP10L2 0.77 12.66 0.56 2.16e-30 Gastritis; LIHC cis rs11864453 0.647 rs8043606 chr16:72135319 T/C cg01557791 chr16:72042693 DHODH -0.45 -7.52 -0.38 4.95e-13 Fibrinogen levels; LIHC cis rs72653721 0.627 rs12662634 chr6:11074191 G/A cg13562911 chr6:11044106 ELOVL2 0.51 7.25 0.37 2.75e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs12478296 0.792 rs3924263 chr2:243005167 A/C cg18898632 chr2:242989856 NA -0.47 -6.5 -0.33 2.86e-10 Obesity-related traits; LIHC cis rs2153535 0.541 rs7774752 chr6:8468978 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs12701220 0.690 rs10243973 chr7:1064983 T/C cg18765753 chr7:1198926 ZFAND2A -0.41 -5.89 -0.3 9.08e-9 Bronchopulmonary dysplasia; LIHC cis rs3789045 0.774 rs12039365 chr1:204488687 A/G cg17419461 chr1:204415978 PIK3C2B -0.43 -6.6 -0.34 1.61e-10 Educational attainment (college completion); LIHC cis rs67460515 0.630 rs7638370 chr3:160921793 G/T cg03342759 chr3:160939853 NMD3 -0.61 -9.1 -0.44 7.44e-18 Parkinson's disease; LIHC cis rs4563143 0.514 rs73029076 chr19:29292032 G/T cg04546413 chr19:29218101 NA 0.5 8.46 0.42 7.92e-16 Methadone dose in opioid dependence; LIHC cis rs875971 0.862 rs1981799 chr7:65955559 T/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs7107174 1.000 rs2256464 chr11:77917305 C/A cg02023728 chr11:77925099 USP35 0.43 7.88 0.39 4.46e-14 Testicular germ cell tumor; LIHC trans rs6446298 1.000 rs6446298 chr3:49860854 T/C cg21659725 chr3:3221576 CRBN 0.72 11.66 0.53 1.14e-26 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs62269547 chr3:134214042 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.96 -0.31 6.34e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs116095464 0.558 rs10075018 chr5:239175 G/A cg00938859 chr5:1591904 SDHAP3 0.58 7.07 0.36 8.53e-12 Breast cancer; LIHC cis rs40363 0.645 rs250627 chr16:3527050 G/A cg00484396 chr16:3507460 NAT15 0.45 7.93 0.39 3.17e-14 Tuberculosis; LIHC cis rs11628318 0.515 rs11850580 chr14:103156586 C/T cg12046867 chr14:103022105 NA 0.4 6.12 0.31 2.62e-9 Platelet count; LIHC cis rs12594515 0.967 rs67854274 chr15:45990518 A/G cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC cis rs6964587 0.869 rs10242792 chr7:91492103 A/C cg17063962 chr7:91808500 NA 0.96 18.26 0.7 1.78e-52 Breast cancer; LIHC cis rs11098499 0.909 rs10020034 chr4:120294331 A/G cg09307838 chr4:120376055 NA 0.76 11.49 0.53 4.66e-26 Corneal astigmatism; LIHC cis rs10791097 0.694 rs11222369 chr11:130744670 A/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2370759 1.000 rs76998371 chr10:32631785 A/G cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs1113500 0.933 rs61797344 chr1:108622580 C/T cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.92e-12 Growth-regulated protein alpha levels; LIHC cis rs897984 0.568 rs4889651 chr16:30895545 C/T cg02466173 chr16:30829666 NA -0.41 -6.2 -0.32 1.59e-9 Dementia with Lewy bodies; LIHC cis rs7523273 0.586 rs2796276 chr1:207951513 G/A cg22525895 chr1:207977042 MIR29B2 0.63 10.22 0.48 1.38e-21 Schizophrenia; LIHC cis rs826838 0.804 rs6580755 chr12:39159190 C/T cg13010199 chr12:38710504 ALG10B 0.52 6.28 0.32 1.04e-9 Heart rate; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22624212 chr21:44298959 WDR4 0.42 6.57 0.33 1.82e-10 Cognitive function; LIHC cis rs7927592 0.513 rs7950129 chr11:68202903 A/G cg16797656 chr11:68205561 LRP5 0.6 10.98 0.51 3.05e-24 Total body bone mineral density; LIHC cis rs6456156 0.586 rs7746628 chr6:167483235 A/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.51 -0.42 5.66e-16 Primary biliary cholangitis; LIHC cis rs12594515 0.967 rs12595138 chr15:45986108 G/C cg19682013 chr15:45996608 NA 0.41 7.16 0.36 4.83e-12 Waist circumference;Weight; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19824334 chr17:73851399 WBP2 0.44 6.38 0.33 5.71e-10 Lung function (FEV1/FVC); LIHC cis rs1707322 0.721 rs11211157 chr1:46132844 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs80282103 0.764 rs12268949 chr10:1104257 A/G cg18964960 chr10:1102726 WDR37 0.67 6.21 0.32 1.53e-9 Glomerular filtration rate (creatinine); LIHC cis rs1046896 0.520 rs9895409 chr17:80902719 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.39 6.01 0.31 4.89e-9 Glycated hemoglobin levels; LIHC cis rs1552244 0.572 rs59132826 chr3:10169725 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg01670876 chr14:74891361 TMEM90A -0.58 -6.78 -0.34 5.31e-11 Mild influenza (H1N1) infection; LIHC cis rs7552404 1.000 rs11161521 chr1:76216330 T/C cg22875332 chr1:76189707 ACADM 0.46 6.74 0.34 6.88e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs988712 0.672 rs925947 chr11:27667367 G/T cg18117895 chr11:27722066 BDNF 0.49 6.85 0.35 3.45e-11 Obesity; LIHC cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg21522988 chr12:29376872 FAR2 0.29 6.39 0.33 5.52e-10 QT interval; LIHC cis rs763121 0.853 rs4821812 chr22:39075235 G/C cg14440974 chr22:39074834 NA -0.45 -7.3 -0.37 2.09e-12 Menopause (age at onset); LIHC cis rs6545883 0.894 rs4672436 chr2:61603357 A/C cg14146966 chr2:61757674 XPO1 -0.44 -7.3 -0.37 2.09e-12 Tuberculosis; LIHC cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg11644478 chr21:40555479 PSMG1 0.77 9.67 0.46 9.97e-20 Cognitive function; LIHC cis rs28595532 0.545 rs13101451 chr4:119253427 A/G cg21605333 chr4:119757512 SEC24D 0.79 6.65 0.34 1.19e-10 Cannabis dependence symptom count; LIHC cis rs9419702 0.639 rs9419624 chr10:133534822 G/A cg20568497 chr10:133558893 NA 0.41 6.11 0.31 2.7e-9 Survival in rectal cancer; LIHC cis rs611744 0.870 rs635941 chr8:109235457 G/A cg21045802 chr8:109455806 TTC35 0.57 9.56 0.46 2.41e-19 Dupuytren's disease; LIHC cis rs2191566 0.959 rs7256345 chr19:44510905 T/G cg20607764 chr19:44506953 ZNF230 -0.45 -7.51 -0.38 5.32e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs7729447 0.776 rs17442964 chr5:32693916 G/A cg16267343 chr5:32710456 NPR3 0.48 5.86 0.3 1.09e-8 Blood pressure; LIHC trans rs2262909 0.853 rs56207853 chr19:22292357 C/T cg17074339 chr11:11642133 GALNTL4 0.45 7.01 0.35 1.3e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg03517284 chr6:25882590 NA -0.63 -7.77 -0.39 9.29e-14 Intelligence (multi-trait analysis); LIHC cis rs4638749 0.677 rs9631035 chr2:108818916 C/T cg25838818 chr2:108905173 SULT1C2 -0.4 -7.0 -0.35 1.37e-11 Blood pressure; LIHC cis rs8072100 0.676 rs7221345 chr17:45405144 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.38 -6.18 -0.32 1.85e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10751667 0.666 rs6597960 chr11:977036 C/T cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs9486719 1.000 rs2472888 chr6:96865501 T/C cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs644799 0.710 rs3017756 chr11:95537358 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.76 13.11 0.58 4.33e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs72781680 0.898 rs12623316 chr2:24087857 A/G cg08917208 chr2:24149416 ATAD2B 0.88 8.29 0.41 2.69e-15 Lymphocyte counts; LIHC cis rs2832077 0.689 rs2832055 chr21:30132382 C/G cg24692254 chr21:30365293 RNF160 0.47 7.19 0.36 4.12e-12 Cognitive test performance; LIHC cis rs344364 0.511 rs2982446 chr16:1947153 C/T cg26897989 chr16:1907736 C16orf73 -0.47 -5.92 -0.3 7.79e-9 Glomerular filtration rate in chronic kidney disease; LIHC trans rs1814175 0.817 rs3974439 chr11:50022607 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs7264396 0.563 rs7268195 chr20:34339854 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.6 -8.61 -0.42 2.68e-16 Total cholesterol levels; LIHC cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg13047869 chr3:10149882 C3orf24 0.52 6.31 0.32 8.85e-10 Alzheimer's disease; LIHC cis rs904251 0.864 rs2797801 chr6:37487161 A/G cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.48e-9 Cognitive performance; LIHC cis rs1577917 0.771 rs9294337 chr6:86248460 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 8.11 0.4 9.35e-15 Response to antipsychotic treatment; LIHC trans rs11157436 0.918 rs1983522 chr14:22618541 G/A cg13567813 chr19:50879636 NR1H2 0.43 6.28 0.32 1.02e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs17401966 0.838 rs61775887 chr1:10284733 T/C cg19773385 chr1:10388646 KIF1B -0.39 -7.02 -0.35 1.23e-11 Hepatocellular carcinoma; LIHC cis rs72781680 1.000 rs56068891 chr2:24230633 A/G cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs1395 1.000 rs1275537 chr2:27441302 C/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.4 -5.73 -0.3 2.17e-8 Blood metabolite levels; LIHC cis rs875971 0.964 rs778708 chr7:65856319 T/C cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs7666738 0.791 rs1426661 chr4:98874303 C/G cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs7617773 0.674 rs13069029 chr3:48355024 A/G cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs2153535 0.580 rs1335641 chr6:8487860 G/T cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs929354 0.742 rs2006844 chr7:157002851 G/A cg17757837 chr7:157058334 UBE3C 0.74 12.1 0.55 2.67e-28 Body mass index; LIHC cis rs7296418 0.663 rs28450974 chr12:123861420 G/A cg00376283 chr12:123451042 ABCB9 0.62 10.35 0.49 5.15e-22 Platelet count; LIHC cis rs9788682 1.000 rs7181245 chr15:78814389 C/T cg06917634 chr15:78832804 PSMA4 -0.5 -7.22 -0.36 3.4e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs875971 0.862 rs17747530 chr7:65994729 G/C cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.34e-9 Aortic root size; LIHC cis rs6089829 0.925 rs6122087 chr20:61664553 T/C cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg03452623 chr4:187889614 NA -0.32 -8.38 -0.41 1.38e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs12464559 0.649 rs4510224 chr2:152593795 C/T cg01189475 chr2:152685088 ARL5A 0.64 7.22 0.36 3.4e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs4689388 0.929 rs1046320 chr4:6304344 C/T cg00701064 chr4:6280414 WFS1 0.44 7.44 0.37 8.11e-13 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs9649465 0.806 rs6971297 chr7:123293342 A/T cg03229431 chr7:123269106 ASB15 -0.39 -8.3 -0.41 2.38e-15 Migraine; LIHC cis rs34172651 0.917 rs17771137 chr16:24792242 G/A cg04756594 chr16:24857601 SLC5A11 0.47 7.25 0.37 2.71e-12 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC cis rs2991971 0.967 rs10789465 chr1:45971759 T/C cg24296786 chr1:45957014 TESK2 0.59 9.36 0.45 1.11e-18 High light scatter reticulocyte count; LIHC cis rs5769765 0.671 rs138844 chr22:50184484 T/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.54 -6.63 -0.34 1.34e-10 Schizophrenia; LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg11965913 chr1:205819406 PM20D1 0.76 11.25 0.52 3.28e-25 Menarche (age at onset); LIHC cis rs9549328 0.878 rs9577407 chr13:113639671 G/A cg00071026 chr13:113650936 MCF2L -0.37 -5.88 -0.3 9.52e-9 Systolic blood pressure; LIHC cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg09323728 chr8:95962352 TP53INP1 -0.35 -7.71 -0.38 1.4e-13 Type 2 diabetes; LIHC cis rs7412746 0.611 rs36008098 chr1:150856806 G/A cg17724175 chr1:150552817 MCL1 0.39 7.79 0.39 8.31e-14 Melanoma; LIHC cis rs2933343 0.700 rs1683777 chr3:128624880 T/G cg25356066 chr3:128598488 ACAD9 0.53 7.47 0.37 6.95e-13 IgG glycosylation; LIHC cis rs17125944 0.686 rs7160582 chr14:53341445 G/T cg00686598 chr14:53173677 PSMC6 0.84 9.12 0.44 6.47e-18 Alzheimer's disease (late onset); LIHC cis rs4700695 0.719 rs27584 chr5:65445232 G/A cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.46e-15 Facial morphology (factor 19); LIHC cis rs9902453 0.845 rs2321493 chr17:28230359 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.03e-27 Coffee consumption (cups per day); LIHC cis rs9303401 0.659 rs34556735 chr17:56694447 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.98 13.02 0.58 9.68e-32 Cognitive test performance; LIHC cis rs8072100 0.840 rs1912482 chr17:45454883 G/A cg25173405 chr17:45401733 C17orf57 -0.41 -5.79 -0.3 1.55e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs812925 0.502 rs6545868 chr2:61655365 T/C cg14146966 chr2:61757674 XPO1 -0.36 -5.96 -0.31 6.23e-9 Immature fraction of reticulocytes; LIHC cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs7165170 0.549 rs10852134 chr15:91099216 G/T cg26821196 chr15:91095069 CRTC3 0.4 7.21 0.36 3.72e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg02869306 chr7:64672164 INTS4L1 0.28 6.19 0.32 1.73e-9 Calcium levels; LIHC cis rs240764 0.717 rs183566 chr6:101142605 A/T cg12253828 chr6:101329408 ASCC3 0.42 6.36 0.33 6.6e-10 Neuroticism; LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg00656387 chr3:40428638 ENTPD3 0.49 8.25 0.41 3.48e-15 Renal cell carcinoma; LIHC cis rs10792665 0.724 rs7131003 chr11:82699180 G/A cg24227371 chr11:82718527 RAB30 -0.38 -9.38 -0.45 9.74e-19 Obesity-related traits; LIHC trans rs1414896 0.692 rs11165355 chr1:95726660 C/T cg24483554 chr1:179544584 NPHS2 0.25 6.11 0.31 2.65e-9 Non-alcoholic fatty liver disease histology (AST); LIHC cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs7776786 0.934 rs13243526 chr7:18812917 C/T cg13420273 chr7:18810212 HDAC9 -0.28 -6.09 -0.31 3.07e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23992171 chr20:33460724 GGT7 -0.54 -7.4 -0.37 1.05e-12 Systolic blood pressure; LIHC cis rs7762018 0.655 rs11966349 chr6:170162537 A/G cg13891659 chr6:170190454 C6orf122;C6orf208 -0.62 -7.97 -0.4 2.35e-14 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs1577917 0.839 rs12055653 chr6:86546663 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.28 -0.37 2.32e-12 Response to antipsychotic treatment; LIHC cis rs11690935 0.595 rs788166 chr2:172915489 G/C cg13550731 chr2:172543902 DYNC1I2 0.56 9.57 0.46 2.23e-19 Schizophrenia; LIHC cis rs921968 0.613 rs2710250 chr2:219543277 A/G cg02985541 chr2:219472218 PLCD4 -0.39 -6.52 -0.33 2.58e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1387259 0.859 rs2054905 chr12:48687951 A/G cg21466736 chr12:48725269 NA -0.7 -10.76 -0.5 1.83e-23 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs2176862 1.000 rs73073732 chr3:46620238 G/A cg08058988 chr3:46621936 LRRC2;TDGF1 -0.6 -6.32 -0.32 8.15e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs10751667 0.666 rs4074233 chr11:977685 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg06343869 chr13:115079967 ZNF828 -0.41 -6.18 -0.32 1.78e-9 Morning vs. evening chronotype; LIHC cis rs1707322 0.663 rs3935296 chr1:46180470 T/C cg06784218 chr1:46089804 CCDC17 -0.42 -7.78 -0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7772486 0.790 rs2253654 chr6:146199445 T/C cg23711669 chr6:146136114 FBXO30 0.73 13.13 0.58 3.7e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs11122272 0.735 rs2790884 chr1:231531932 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.36 0.45 1.08e-18 Hemoglobin concentration; LIHC cis rs807029 0.577 rs701835 chr10:102762127 A/G cg27255678 chr10:102756921 LZTS2 0.52 7.25 0.36 2.89e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg20607798 chr8:58055168 NA 0.49 6.13 0.31 2.37e-9 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.49 0.42 6.51e-16 Platelet count; LIHC cis rs116095464 0.558 rs10462754 chr5:246669 T/C cg22857025 chr5:266934 NA -1.47 -17.98 -0.7 2.32e-51 Breast cancer; LIHC cis rs1707322 1.000 rs11211205 chr1:46321874 C/T cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg13152130 chr6:118910203 C6orf204 -0.64 -6.95 -0.35 1.83e-11 Diastolic blood pressure; LIHC cis rs929354 0.772 rs6954050 chr7:156978554 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.87 -0.3 1.03e-8 Body mass index; LIHC cis rs11758351 1.000 rs79868973 chr6:26189312 C/G cg03854865 chr6:26224070 HIST1H3E 0.66 7.18 0.36 4.4e-12 Gout;Renal underexcretion gout; LIHC cis rs10089 0.953 rs6875982 chr5:127529197 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.27 0.32 1.09e-9 Ileal carcinoids; LIHC cis rs17685 0.712 rs9800948 chr7:75810473 A/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.87 -0.39 4.6e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs589448 0.902 rs642786 chr12:69758462 T/C cg20891283 chr12:69753455 YEATS4 0.95 22.45 0.77 3.15e-69 Cerebrospinal fluid biomarker levels; LIHC trans rs11098499 0.604 rs34278750 chr4:120571136 G/A cg25214090 chr10:38739885 LOC399744 0.54 8.61 0.42 2.63e-16 Corneal astigmatism; LIHC cis rs2274273 1.000 rs7142704 chr14:55630603 C/A cg01864836 chr14:55583639 NA -0.36 -6.65 -0.34 1.16e-10 Protein biomarker; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg23131131 chr22:24373011 LOC391322 0.63 9.39 0.45 8.96e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.06 12.22 0.55 9.68e-29 Platelet count; LIHC cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.69 11.13 0.52 9e-25 Height; LIHC cis rs9596863 1.000 rs1379831 chr13:54418506 C/G ch.13.53330881F chr13:54432880 NA 0.42 5.85 0.3 1.15e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs6088580 0.668 rs1205337 chr20:32926041 T/A cg08999081 chr20:33150536 PIGU -0.67 -13.19 -0.58 2.08e-32 Glomerular filtration rate (creatinine); LIHC cis rs3749237 0.595 rs6784820 chr3:49450864 C/T cg06212747 chr3:49208901 KLHDC8B -0.45 -5.84 -0.3 1.2e-8 Resting heart rate; LIHC cis rs2153535 0.580 rs9378551 chr6:8463744 A/G cg21535247 chr6:8435926 SLC35B3 0.62 8.15 0.4 6.8e-15 Motion sickness; LIHC cis rs7903847 0.642 rs7909345 chr10:99150794 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6570726 0.577 rs9497315 chr6:145791967 C/T cg05347473 chr6:146136440 FBXO30 -0.45 -6.26 -0.32 1.14e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 0.586 rs11710086 chr3:161125858 A/T cg03342759 chr3:160939853 NMD3 -0.54 -8.53 -0.42 4.75e-16 Morning vs. evening chronotype; LIHC cis rs9640161 0.750 rs11538922 chr7:150035183 C/T cg17279839 chr7:150038598 RARRES2 0.6 12.1 0.55 2.77e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg05185784 chr16:90016020 DEF8 -0.47 -6.11 -0.31 2.68e-9 Skin colour saturation; LIHC cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg05564831 chr3:52568323 NT5DC2 0.36 6.04 0.31 4.01e-9 Electroencephalogram traits; LIHC cis rs634534 0.562 rs661335 chr11:65754061 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.41 6.18 0.32 1.8e-9 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg03119618 chr19:38572401 SIPA1L3 0.4 6.46 0.33 3.69e-10 Oropharynx cancer; LIHC trans rs10213084 0.920 rs1104532 chr4:147519769 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.46 6.64 0.34 1.23e-10 Heart rate; LIHC cis rs4660261 0.526 rs2906466 chr1:44322220 A/G cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Intelligence (multi-trait analysis); LIHC cis rs1801251 1.000 rs6738386 chr2:233602028 T/C cg08000102 chr2:233561755 GIGYF2 0.75 11.3 0.52 2.24e-25 Coronary artery disease; LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs10751667 0.643 rs6597970 chr11:928669 C/A cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC cis rs16912285 0.688 rs1899541 chr11:24339624 T/C ch.11.24196551F chr11:24239977 NA 0.75 9.67 0.46 1.07e-19 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs1008375 1.000 rs2215450 chr4:17675394 T/G cg02297831 chr4:17616191 MED28 0.41 6.59 0.34 1.7e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10426930 0.547 rs2054519 chr19:5059360 T/C cg18473234 chr19:5097819 KDM4B -0.58 -6.96 -0.35 1.78e-11 Monocyte percentage of white cells; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02254876 chr3:42922351 NA -0.39 -6.05 -0.31 3.7e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7917772 0.532 rs10748829 chr10:104527244 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -5.78 -0.3 1.66e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6752107 1.000 rs6752107 chr2:234161448 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.57 8.73 0.43 1.16e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs6977660 1.000 rs13233821 chr7:19813637 A/C cg07541023 chr7:19748670 TWISTNB 0.37 5.92 0.31 7.63e-9 Thyroid stimulating hormone; LIHC cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg09904177 chr6:26538194 HMGN4 0.57 11.21 0.52 4.9e-25 Intelligence (multi-trait analysis); LIHC cis rs12908161 0.959 rs61074241 chr15:85333396 C/T cg12863693 chr15:85201151 NMB 0.48 6.44 0.33 3.97e-10 Schizophrenia; LIHC cis rs6933660 0.800 rs3800273 chr6:151759035 G/C cg10883421 chr6:151773342 RMND1;C6orf211 0.62 10.09 0.48 3.89e-21 Menarche (age at onset); LIHC cis rs2576037 0.526 rs605487 chr18:44444778 G/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.73e-12 Personality dimensions; LIHC cis rs8180040 0.800 rs2088135 chr3:47280018 T/C cg16586182 chr3:47516702 SCAP 0.51 9.01 0.44 1.45e-17 Colorectal cancer; LIHC cis rs922107 0.738 rs10922667 chr1:90039527 T/A cg15422784 chr1:90023713 LRRC8B -0.47 -7.56 -0.38 3.64e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs11190604 1.000 rs4919468 chr10:102288343 G/C cg07080220 chr10:102295463 HIF1AN 0.58 8.22 0.41 4.19e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs4906332 1.000 rs2065018 chr14:103879187 C/T cg26031613 chr14:104095156 KLC1 0.4 5.82 0.3 1.38e-8 Coronary artery disease; LIHC cis rs4555082 0.874 rs78923231 chr14:105754033 C/T cg10792982 chr14:105748885 BRF1 0.49 6.36 0.33 6.41e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs921968 0.541 rs4674314 chr2:219423520 A/G cg02176678 chr2:219576539 TTLL4 -0.57 -7.9 -0.39 3.73e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs11122272 0.637 rs2808593 chr1:231524228 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC trans rs61931739 0.534 rs11052979 chr12:34035774 G/T cg26384229 chr12:38710491 ALG10B 0.52 7.21 0.36 3.62e-12 Morning vs. evening chronotype; LIHC cis rs1355223 0.902 rs860712 chr11:34743494 C/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7903847 0.642 rs2297667 chr10:99145492 A/T cg20016023 chr10:99160130 RRP12 -0.41 -6.62 -0.34 1.4e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs798554 0.607 rs1182151 chr7:2909225 C/G cg13628971 chr7:2884303 GNA12 0.55 7.77 0.39 9.17e-14 Height; LIHC cis rs6840360 0.615 rs72728179 chr4:152477877 A/G cg22705602 chr4:152727874 NA -0.32 -6.34 -0.32 7.15e-10 Intelligence (multi-trait analysis); LIHC cis rs7937890 0.874 rs2303972 chr11:14303282 T/A cg22961513 chr11:14280813 SPON1 0.5 7.67 0.38 1.78e-13 Mitochondrial DNA levels; LIHC cis rs9399135 0.967 rs3756799 chr6:135341011 A/G cg22676075 chr6:135203613 NA 0.4 6.41 0.33 4.74e-10 Red blood cell count; LIHC cis rs17826219 0.500 rs2874724 chr17:29072433 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Body mass index; LIHC cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.5 0.38 5.43e-13 Bipolar disorder; LIHC cis rs7927592 0.645 rs7936582 chr11:68292930 T/C cg20283391 chr11:68216788 NA -0.39 -6.04 -0.31 4.1e-9 Total body bone mineral density; LIHC trans rs62103177 0.525 rs612913 chr18:77845882 A/G cg05926928 chr17:57297772 GDPD1 -0.61 -6.82 -0.35 4.06e-11 Opioid sensitivity; LIHC cis rs7615952 0.599 rs6438955 chr3:125730333 C/A cg05084668 chr3:125655381 ALG1L -0.42 -7.0 -0.35 1.39e-11 Blood pressure (smoking interaction); LIHC cis rs10847980 0.590 rs1696326 chr12:123311981 A/G cg22842854 chr12:123319900 HIP1R -0.8 -8.98 -0.44 1.82e-17 Adiponectin levels; LIHC cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg24549020 chr5:56110836 MAP3K1 0.56 7.32 0.37 1.82e-12 Initial pursuit acceleration; LIHC cis rs17253792 0.822 rs28681420 chr14:56088403 G/T cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03149093 chr19:12035973 ZNF700 0.48 6.54 0.33 2.26e-10 Lung function (FEV1/FVC); LIHC cis rs988712 0.672 rs16917237 chr11:27702383 A/C cg18117895 chr11:27722066 BDNF -0.52 -7.18 -0.36 4.36e-12 Obesity; LIHC cis rs6582630 0.555 rs10880613 chr12:38509553 C/T cg26384229 chr12:38710491 ALG10B 0.96 12.69 0.57 1.68e-30 Drug-induced liver injury (flucloxacillin); LIHC cis rs2762353 0.603 rs12201071 chr6:25778055 C/T cg12310025 chr6:25882481 NA 0.48 6.42 0.33 4.63e-10 Blood metabolite levels; LIHC cis rs6831352 0.734 rs1154400 chr4:100010010 C/T cg12011299 chr4:100065546 ADH4 0.58 10.25 0.48 1.11e-21 Alcohol dependence; LIHC cis rs600806 0.888 rs6695482 chr1:109870859 C/G cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.31 -0.37 1.89e-12 Intelligence (multi-trait analysis); LIHC cis rs45544231 0.544 rs9931232 chr16:52572832 A/G cg09051775 chr16:52580266 TOX3 0.31 5.73 0.3 2.25e-8 Restless legs syndrome; LIHC cis rs1878931 0.501 rs9921169 chr16:3421261 A/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.7 10.5 0.49 1.56e-22 Body mass index (adult); LIHC cis rs7582180 0.845 rs11683088 chr2:100920667 C/T cg14675211 chr2:100938903 LONRF2 0.53 7.98 0.4 2.29e-14 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.581 rs6671303 chr1:46629653 A/C cg01431908 chr1:46668882 C1orf190;POMGNT1 -0.51 -7.89 -0.39 4.06e-14 Red blood cell count;Reticulocyte count; LIHC cis rs9858542 0.953 rs34363169 chr3:49537712 G/A cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18635645 chr1:85667791 SYDE2 0.47 6.87 0.35 3e-11 Pancreatic cancer; LIHC cis rs3008870 0.583 rs11208985 chr1:67464666 G/A cg08660285 chr1:67390436 MIER1;WDR78 -0.87 -13.34 -0.59 5.45e-33 Lymphocyte percentage of white cells; LIHC cis rs4819052 0.807 rs4819047 chr21:46665139 C/T cg22633049 chr21:46681294 NA -0.38 -6.48 -0.33 3.16e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7586673 0.893 rs889925 chr2:161971597 T/C cg16506815 chr2:162101123 NA 0.5 8.2 0.41 4.99e-15 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs68153882 chr3:10013110 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs62458065 0.713 rs62463968 chr7:32501242 G/A cg06627557 chr7:32535165 LSM5;AVL9 -0.62 -6.14 -0.31 2.33e-9 Metabolite levels (HVA/MHPG ratio); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg25074458 chr19:9946388 PIN1 0.43 6.54 0.33 2.27e-10 Alopecia areata; LIHC trans rs1814175 0.935 rs11040438 chr11:49622521 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -21.37 -0.76 5.99e-65 Height; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17327406 chr4:6303265 WFS1 0.42 6.23 0.32 1.35e-9 Longevity; LIHC cis rs9399135 0.967 rs1041480 chr6:135373076 G/T cg24558204 chr6:135376177 HBS1L 0.44 7.19 0.36 4.05e-12 Red blood cell count; LIHC cis rs10128251 0.743 rs2386636 chr10:5712087 G/T cg24097872 chr10:5724021 NA 0.72 11.12 0.52 9.72e-25 Childhood ear infection; LIHC cis rs1568889 0.838 rs10835283 chr11:28214985 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.14 0.61 4.57e-36 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04024839 chr7:99613205 ZKSCAN1 -0.47 -6.6 -0.34 1.54e-10 Pancreatic cancer; LIHC cis rs743757 1.000 rs2282754 chr3:50436827 T/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.46 6.45 0.33 3.85e-10 Diastolic blood pressure; LIHC cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg19774624 chr17:42201019 HDAC5 -0.82 -12.54 -0.56 6.04e-30 Total body bone mineral density; LIHC trans rs3749237 1.000 rs11710675 chr3:49751900 C/A cg21659725 chr3:3221576 CRBN 0.79 12.75 0.57 1.01e-30 Resting heart rate; LIHC cis rs6088590 0.687 rs8115656 chr20:33282780 G/C cg08999081 chr20:33150536 PIGU 0.61 11.36 0.52 1.36e-25 Coronary artery disease; LIHC cis rs6754311 0.731 rs748841 chr2:136558157 C/T cg07169764 chr2:136633963 MCM6 -0.66 -9.92 -0.47 1.51e-20 Mosquito bite size; LIHC trans rs4906332 1.000 rs2065017 chr14:103879579 T/C cg17675199 chr6:35436792 RPL10A 0.31 6.1 0.31 2.85e-9 Coronary artery disease; LIHC cis rs2292864 0.764 rs35265764 chr17:45363546 G/T cg18085866 chr17:45331354 ITGB3 -0.58 -6.56 -0.33 1.96e-10 Left atrial antero-posterior diameter; LIHC cis rs11229555 1.000 rs11229555 chr11:58408687 G/T cg15696309 chr11:58395628 NA -0.74 -9.24 -0.45 2.64e-18 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs5758511 0.637 rs5751244 chr22:42617411 T/C cg20195005 chr22:42527684 CYP2D6 0.31 5.89 0.3 9.05e-9 Birth weight; LIHC cis rs56235845 0.685 rs35630910 chr5:176757841 A/C cg17509989 chr5:176798049 RGS14 0.75 8.76 0.43 8.9e-17 Hemoglobin concentration;Hematocrit; LIHC cis rs7937682 0.924 rs501089 chr11:111502479 G/T cg09085632 chr11:111637200 PPP2R1B 1.01 11.52 0.53 3.47e-26 Primary sclerosing cholangitis; LIHC cis rs11577318 0.853 rs11803933 chr1:26629465 G/C cg18121669 chr1:26560928 CCDC21 0.5 8.0 0.4 1.91e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg07061783 chr6:25882402 NA -0.48 -6.69 -0.34 9.05e-11 Blood metabolite levels; LIHC trans rs6951245 0.832 rs10266519 chr7:1142977 C/T cg13565492 chr6:43139072 SRF -0.8 -6.4 -0.33 5.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg25894440 chr7:65020034 NA -0.53 -6.17 -0.32 1.93e-9 Diabetic kidney disease; LIHC cis rs10751667 0.621 rs10794353 chr11:948740 A/G ch.11.42038R chr11:967971 AP2A2 0.54 9.81 0.47 3.52e-20 Alzheimer's disease (late onset); LIHC trans rs7618501 0.521 rs2352984 chr3:49948728 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.72 0.34 7.54e-11 Intelligence (multi-trait analysis); LIHC cis rs67478160 0.619 rs1040813 chr14:104306696 T/C cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.49 -0.38 5.81e-13 Schizophrenia; LIHC cis rs8103278 0.507 rs2041975 chr19:46238555 T/C cg02376097 chr19:46275166 DMPK 0.54 9.44 0.45 5.96e-19 Coronary artery disease; LIHC cis rs400736 0.602 rs6694154 chr1:8163520 G/A cg25007680 chr1:8021821 PARK7 -0.54 -8.2 -0.41 4.99e-15 Response to antidepressants and depression; LIHC trans rs6600671 0.934 rs11249429 chr1:121291080 C/T cg09829573 chr1:144692074 NBPF9 0.41 7.46 0.37 7.18e-13 Hip geometry; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg07133347 chr1:107600762 PRMT6 -0.45 -6.89 -0.35 2.62e-11 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs7246657 0.943 rs9917081 chr19:37876616 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs2153535 0.580 rs1928184 chr6:8532108 T/A cg07606381 chr6:8435919 SLC35B3 0.79 11.54 0.53 3.03e-26 Motion sickness; LIHC cis rs875971 1.000 rs6958271 chr7:65979331 A/C cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.6e-11 Aortic root size; LIHC cis rs7534824 0.543 rs72734256 chr1:101390090 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.93 0.39 3.23e-14 Refractive astigmatism; LIHC cis rs847649 0.694 rs11770319 chr7:102770170 C/G cg18108683 chr7:102477205 FBXL13 0.43 6.47 0.33 3.3e-10 Morning vs. evening chronotype; LIHC cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg05025164 chr4:1340916 KIAA1530 0.41 5.92 0.3 8.02e-9 Longevity; LIHC cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg20090690 chr10:134436459 INPP5A 0.44 5.71 0.3 2.44e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11671005 0.735 rs11671591 chr19:58918337 A/G cg25952890 chr19:58913133 NA -0.69 -7.49 -0.38 6.04e-13 Mean platelet volume; LIHC cis rs16912285 0.591 rs7929025 chr11:24363324 A/C ch.11.24196551F chr11:24239977 NA 0.72 8.84 0.43 5.05e-17 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs2439831 0.702 rs28699233 chr15:44122866 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.58 6.32 0.32 7.95e-10 Lung cancer in ever smokers; LIHC cis rs1816752 0.774 rs55888616 chr13:25016092 C/T cg22771759 chr13:24902376 NA 0.32 6.76 0.34 5.94e-11 Obesity-related traits; LIHC cis rs68170813 0.559 rs3823960 chr7:107009349 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.83 -0.3 1.29e-8 Coronary artery disease; LIHC cis rs875971 0.862 rs11763189 chr7:65983529 G/A cg18876405 chr7:65276391 NA 0.35 6.5 0.33 2.81e-10 Aortic root size; LIHC cis rs459571 0.916 rs109536 chr9:136889987 G/C cg13789015 chr9:136890014 NCRNA00094 0.45 8.16 0.4 6.3e-15 Platelet distribution width; LIHC cis rs2072499 0.966 rs6427304 chr1:156156789 A/G cg25208724 chr1:156163844 SLC25A44 0.92 14.88 0.63 6.05e-39 Testicular germ cell tumor; LIHC trans rs11689435 0.925 rs1478594 chr2:218346172 C/T cg13544946 chr9:35729779 TLN1 -0.44 -6.31 -0.32 8.88e-10 Metabolite levels (MHPG); LIHC cis rs763121 0.819 rs5750629 chr22:38985065 T/C cg06022373 chr22:39101656 GTPBP1 0.75 15.25 0.64 1.91e-40 Menopause (age at onset); LIHC cis rs2228479 0.850 rs11640209 chr16:89807828 C/A cg06558623 chr16:89946397 TCF25 0.87 11.88 0.54 1.69e-27 Skin colour saturation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05744073 chr17:1953268 MIR132 0.42 6.92 0.35 2.21e-11 Cognitive function; LIHC cis rs6430585 0.583 rs3769012 chr2:136556480 C/T cg07169764 chr2:136633963 MCM6 1.32 21.27 0.75 1.45e-64 Corneal structure; LIHC cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg06640241 chr16:89574553 SPG7 0.84 15.9 0.65 5.03e-43 Multiple myeloma (IgH translocation); LIHC trans rs668210 0.793 rs507672 chr11:65767153 C/T cg17712092 chr4:129076599 LARP1B -0.58 -6.3 -0.32 9.01e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1008375 1.000 rs10939743 chr4:17662731 G/A cg02297831 chr4:17616191 MED28 0.42 6.66 0.34 1.11e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs76419734 0.510 rs3943980 chr4:106676766 G/A cg24545054 chr4:106630052 GSTCD;INTS12 -0.68 -7.32 -0.37 1.75e-12 Post bronchodilator FEV1; LIHC cis rs796364 0.951 rs971232 chr2:200792881 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.27 0.41 2.94e-15 Schizophrenia; LIHC cis rs40363 0.729 rs6501176 chr16:3522197 A/G cg05754148 chr16:3507555 NAT15 -0.48 -6.45 -0.33 3.88e-10 Tuberculosis; LIHC cis rs1799949 0.965 rs6503727 chr17:41312859 C/T cg05368731 chr17:41323189 NBR1 0.68 11.36 0.52 1.41e-25 Menopause (age at onset); LIHC cis rs17125944 0.686 rs77650471 chr14:53364307 C/T cg00686598 chr14:53173677 PSMC6 0.91 9.87 0.47 2.19e-20 Alzheimer's disease (late onset); LIHC cis rs8078723 0.630 rs60137005 chr17:38129996 A/T cg17467752 chr17:38218738 THRA 0.62 10.78 0.5 1.57e-23 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6500602 0.647 rs4786519 chr16:4584406 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.45 6.55 0.33 2.15e-10 Schizophrenia; LIHC cis rs11148252 0.840 rs3886077 chr13:52949053 C/A cg00495681 chr13:53174319 NA 0.42 6.82 0.35 4.26e-11 Lewy body disease; LIHC cis rs7615952 0.800 rs12489350 chr3:125644116 T/C cg05084668 chr3:125655381 ALG1L -0.54 -7.67 -0.38 1.82e-13 Blood pressure (smoking interaction); LIHC cis rs6430585 0.528 rs56064699 chr2:136595706 G/A cg07169764 chr2:136633963 MCM6 1.28 19.72 0.73 2.38e-58 Corneal structure; LIHC cis rs3749237 0.636 rs1568662 chr3:49521263 A/G cg02487422 chr3:49467188 NICN1 0.41 6.32 0.32 8.18e-10 Resting heart rate; LIHC cis rs9399137 0.507 rs7745289 chr6:135380327 A/G cg24558204 chr6:135376177 HBS1L 0.64 10.67 0.5 4.01e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs4555082 0.834 rs2735817 chr14:105717796 A/G cg13114125 chr14:105738426 BRF1 0.79 10.3 0.49 7.7e-22 Mean platelet volume;Platelet distribution width; LIHC cis rs7296418 0.961 rs4148862 chr12:123568619 A/C cg00376283 chr12:123451042 ABCB9 0.71 12.82 0.57 5.47e-31 Platelet count; LIHC cis rs4853012 0.838 rs72915068 chr2:74356185 G/A cg01017244 chr2:74357527 NA 0.65 12.0 0.54 6.25e-28 Gestational age at birth (maternal effect); LIHC trans rs1814175 0.645 rs1722000 chr11:49917928 A/C cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs875971 0.964 rs6978429 chr7:65959876 T/G cg11764359 chr7:65958608 NA 0.91 16.89 0.67 5.59e-47 Aortic root size; LIHC cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg08219700 chr8:58056026 NA 0.49 6.38 0.33 5.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs7568458 0.684 rs67988001 chr2:85787123 C/T cg02493740 chr2:85810744 VAMP5 -0.48 -7.95 -0.39 2.79e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs763121 0.853 rs3788545 chr22:39065172 A/G cg14440974 chr22:39074834 NA -0.43 -7.0 -0.35 1.37e-11 Menopause (age at onset); LIHC cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg00101154 chr16:420108 MRPL28 -0.6 -8.96 -0.44 2.14e-17 Bone mineral density (spine);Bone mineral density; LIHC cis rs2540917 0.678 rs11900608 chr2:60657362 A/G cg00543073 chr2:60773386 BCL11A -0.31 -6.33 -0.32 7.8e-10 Mean corpuscular volume; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15942720 chr14:51706980 TMX1 -0.54 -6.62 -0.34 1.4e-10 Systolic blood pressure; LIHC cis rs7917772 0.503 rs56219824 chr10:104302337 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11270836 1 rs11270836 chr4:38625915 T/TACATTATGTCATTTCACA cg18361445 chr4:38666374 KLF3;FLJ13197 0.6 8.35 0.41 1.7e-15 Mumps; LIHC cis rs2439831 0.867 rs28461955 chr15:43661459 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.94 17.38 0.68 6.24e-49 Lung cancer in ever smokers; LIHC cis rs7095944 0.613 rs11245366 chr10:126482849 C/T cg20435097 chr10:126320824 FAM53B 0.34 5.79 0.3 1.58e-8 Asthma; LIHC cis rs832187 0.813 rs704368 chr3:63868337 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.47 6.8 0.35 4.75e-11 Schizophrenia; LIHC cis rs4862750 0.914 rs1991256 chr4:187875330 A/G cg22105103 chr4:187893119 NA 0.33 8.09 0.4 1.07e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs10857712 0.950 rs11101744 chr10:135226041 G/C cg19623624 chr10:135278901 LOC619207 -0.4 -6.38 -0.33 5.81e-10 Systemic lupus erythematosus; LIHC cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg24642844 chr7:1081250 C7orf50 -0.92 -8.96 -0.44 2.13e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6964587 0.836 rs757040 chr7:91552016 A/G cg17063962 chr7:91808500 NA -0.9 -13.5 -0.59 1.35e-33 Breast cancer; LIHC cis rs10861342 0.892 rs10459207 chr12:105531072 C/T cg23923672 chr12:105501055 KIAA1033 0.7 8.54 0.42 4.64e-16 IgG glycosylation; LIHC cis rs11674184 0.714 rs9789525 chr2:11724580 G/T cg07314298 chr2:11723111 GREB1 -0.63 -11.94 -0.54 1.09e-27 Endometriosis; LIHC cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg21448741 chr8:58168803 NA 0.33 5.88 0.3 1e-8 Developmental language disorder (linguistic errors); LIHC cis rs9372253 1.000 rs2235989 chr6:110714584 A/T cg01119278 chr6:110721349 DDO -0.31 -6.67 -0.34 1.03e-10 Platelet distribution width; LIHC trans rs6934970 1.000 rs10457250 chr6:113049142 C/A cg09308777 chr6:169852575 NA 0.61 6.22 0.32 1.44e-9 Bipolar disorder (body mass index interaction); LIHC cis rs317689 0.658 rs490872 chr12:69645864 A/G cg14784868 chr12:69753453 YEATS4 0.52 7.34 0.37 1.59e-12 Response to diuretic therapy; LIHC cis rs7208859 0.673 rs9889968 chr17:29220128 C/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg01411255 chr17:61851458 DDX42;CCDC47 -0.76 -14.14 -0.61 4.59e-36 Prudent dietary pattern; LIHC cis rs55665837 0.701 rs11023278 chr11:14641184 G/T cg00085434 chr11:14927489 NA 0.43 5.99 0.31 5.36e-9 Vitamin D levels; LIHC cis rs12765878 0.967 rs7920217 chr10:105668172 C/T cg11005552 chr10:105648138 OBFC1 0.39 6.21 0.32 1.51e-9 Coronary artery disease; LIHC cis rs6952808 0.792 rs11771973 chr7:1950440 C/G cg02951883 chr7:2050386 MAD1L1 -0.62 -9.34 -0.45 1.28e-18 Bipolar disorder and schizophrenia; LIHC cis rs68170813 0.559 rs12534676 chr7:106943640 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs921968 0.541 rs7601872 chr2:219319885 C/G cg02985541 chr2:219472218 PLCD4 -0.42 -6.74 -0.34 6.74e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg20887711 chr4:1340912 KIAA1530 0.49 7.67 0.38 1.86e-13 Obesity-related traits; LIHC cis rs7223966 1.000 rs9903897 chr17:61716705 T/A cg05941027 chr17:61774174 LIMD2 0.31 6.19 0.32 1.69e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs763121 0.853 rs2281020 chr22:39064406 A/G cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.15 -0.48 2.55e-21 Platelet count; LIHC cis rs2273156 0.929 rs7144646 chr14:35454701 C/G cg16230307 chr14:35515116 FAM177A1 -0.41 -5.97 -0.31 6.06e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs7412746 0.611 rs72704679 chr1:150897477 C/T cg17724175 chr1:150552817 MCL1 0.38 7.59 0.38 3.03e-13 Melanoma; LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.547 rs11714419 chr3:52628816 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.47 0.33 3.38e-10 Bipolar disorder; LIHC cis rs6938 0.534 rs1130741 chr15:75189930 A/G cg14664628 chr15:75095509 CSK -0.47 -6.56 -0.33 1.94e-10 Breast cancer; LIHC cis rs9733 0.596 rs72700897 chr1:150626038 C/G cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg20295408 chr7:1910781 MAD1L1 -0.43 -6.45 -0.33 3.93e-10 Schizophrenia; LIHC cis rs1005277 0.579 rs1740745 chr10:38520056 T/C cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs3770081 1.000 rs61477982 chr2:86160532 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.69 -6.23 -0.32 1.33e-9 Facial emotion recognition (sad faces); LIHC cis rs2820315 0.505 rs10800792 chr1:201811144 G/A cg11586189 chr1:201857591 SHISA4 0.53 8.62 0.42 2.59e-16 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; LIHC cis rs9660992 0.573 rs1172139 chr1:205213962 G/A cg21545522 chr1:205238299 TMCC2 0.37 7.1 0.36 7.18e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs6570726 0.599 rs9403725 chr6:145897622 A/T cg13319975 chr6:146136371 FBXO30 0.55 8.23 0.41 4e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08137080 chr1:16482430 EPHA2 0.4 6.24 0.32 1.28e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7654585 1.000 rs7654585 chr4:25942751 A/G cg10409131 chr4:25915609 C4orf52 0.48 7.39 0.37 1.17e-12 Obesity-related traits; LIHC cis rs858239 0.600 rs6461690 chr7:23135534 A/G cg23682824 chr7:23144976 KLHL7 0.42 6.29 0.32 9.59e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs6089584 0.546 rs6061980 chr20:60618877 G/A cg06108461 chr20:60628389 TAF4 -0.62 -8.51 -0.42 5.62e-16 Body mass index; LIHC cis rs7017697 1.000 rs10092772 chr8:19686385 A/T cg17834443 chr8:19674713 INTS10 -0.41 -6.41 -0.33 4.71e-10 Breast cancer; LIHC cis rs9494142 0.592 rs1547247 chr6:135390836 C/T cg22676075 chr6:135203613 NA 0.56 8.11 0.4 9.11e-15 Lymphocyte counts;Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs2243480 1.000 rs1167613 chr7:65487439 C/T cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs4728302 0.869 rs958404 chr7:133597186 G/T cg10665199 chr7:133106180 EXOC4 -0.36 -6.13 -0.31 2.41e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg09222892 chr1:25734099 RHCE -0.48 -8.9 -0.43 3.32e-17 Erythrocyte sedimentation rate; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg10164272 chr16:89456328 ANKRD11 0.46 6.57 0.33 1.9e-10 Alopecia areata; LIHC cis rs6088590 1.000 rs6087625 chr20:33342477 A/G cg24642439 chr20:33292090 TP53INP2 -0.83 -12.1 -0.55 2.72e-28 Coronary artery disease; LIHC cis rs3806933 0.522 rs13153937 chr5:110434307 C/T cg04022379 chr5:110408740 TSLP 0.6 9.71 0.46 7.43e-20 Eosinophilic esophagitis; LIHC cis rs2070433 1.000 rs11701310 chr21:47962836 G/C cg12379764 chr21:47803548 PCNT 0.63 8.78 0.43 7.84e-17 Lymphocyte counts; LIHC trans rs2727020 0.724 rs4109837 chr11:49372051 A/T cg15704280 chr7:45808275 SEPT13 -0.74 -11.25 -0.52 3.48e-25 Coronary artery disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00166836 chr6:149721425 MAP3K7IP2;SUMO4 -0.44 -6.66 -0.34 1.08e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7937890 0.559 rs2575825 chr11:14472096 T/C cg02886208 chr11:14281011 SPON1 -0.46 -6.58 -0.34 1.75e-10 Mitochondrial DNA levels; LIHC cis rs2758596 0.826 rs2251615 chr1:156202300 C/T cg25208724 chr1:156163844 SLC25A44 0.75 7.76 0.39 9.6e-14 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs1448094 0.512 rs7137596 chr12:86239884 C/G cg02569458 chr12:86230093 RASSF9 0.48 6.38 0.33 5.82e-10 Major depressive disorder; LIHC cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7246657 0.943 rs4803347 chr19:37848017 G/A cg23950597 chr19:37808831 NA -0.44 -5.93 -0.31 7.54e-9 Coronary artery calcification; LIHC cis rs10744422 1.000 rs4993320 chr12:123338092 T/C cg22842854 chr12:123319900 HIP1R -0.74 -9.83 -0.47 2.99e-20 Schizophrenia; LIHC cis rs6690583 0.697 rs4907126 chr1:85523453 C/T cg22153463 chr1:85462885 MCOLN2 0.54 8.47 0.42 7.32e-16 Serum sulfate level; LIHC cis rs6424115 0.767 rs11591202 chr1:24102080 A/C cg08896387 chr1:24191740 FUCA1 0.37 5.95 0.31 6.74e-9 Immature fraction of reticulocytes; LIHC cis rs7617773 0.780 rs11714176 chr3:48360862 C/T cg11946769 chr3:48343235 NME6 0.92 11.7 0.53 7.75e-27 Coronary artery disease; LIHC cis rs6430585 0.583 rs4988145 chr2:136632300 A/C cg15123519 chr2:136567270 LCT -0.38 -6.08 -0.31 3.3e-9 Corneal structure; LIHC cis rs796364 1.000 rs281759 chr2:200787719 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.24 0.41 3.73e-15 Schizophrenia; LIHC cis rs4819052 0.851 rs3673 chr21:46681775 C/T cg22633049 chr21:46681294 NA -0.36 -6.28 -0.32 1.05e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2836974 0.549 rs34160989 chr21:40554118 C/G cg11644478 chr21:40555479 PSMG1 0.72 6.37 0.33 6.12e-10 Cognitive function; LIHC cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.39e-8 Menopause (age at onset); LIHC cis rs7659604 0.592 rs56077950 chr4:122721412 C/T cg19748678 chr4:122722346 EXOSC9 0.67 11.04 0.51 1.99e-24 Type 2 diabetes; LIHC cis rs2290416 0.892 rs76225457 chr8:144666052 G/T cg26536354 chr8:144654954 C8orf73 0.56 6.4 0.33 5.22e-10 Attention deficit hyperactivity disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03944305 chr16:28222588 XPO6 0.42 6.19 0.32 1.71e-9 Lung function (FEV1/FVC); LIHC cis rs2836950 0.545 rs1888489 chr21:40533164 T/C cg06238570 chr21:40685208 BRWD1 -0.4 -6.48 -0.33 3.19e-10 Menarche (age at onset); LIHC cis rs798502 0.522 rs7790322 chr7:2830498 C/T cg13628971 chr7:2884303 GNA12 0.38 6.17 0.32 1.88e-9 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Inflammatory bowel disease;Waist circumference adjusted for BMI in non-smokers;Ulcerative colitis;Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs780096 0.546 rs2293572 chr2:27728777 C/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 0.42 6.34 0.32 7.47e-10 Total body bone mineral density; LIHC cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.45e-18 Bipolar disorder; LIHC cis rs7395581 0.959 rs7120118 chr11:47286290 T/C cg25783544 chr11:47291846 MADD 0.43 6.28 0.32 1.01e-9 HDL cholesterol; LIHC cis rs7106204 0.562 rs7109606 chr11:24251314 G/T ch.11.24196551F chr11:24239977 NA 0.83 11.82 0.54 2.81e-27 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs2274273 0.840 rs7153110 chr14:55820628 A/G cg01864836 chr14:55583639 NA -0.4 -7.5 -0.38 5.55e-13 Protein biomarker; LIHC cis rs17102423 0.723 rs55658675 chr14:65554638 C/T cg11161011 chr14:65562177 MAX -0.53 -7.58 -0.38 3.19e-13 Obesity-related traits; LIHC cis rs11603020 0.851 rs10896631 chr11:57381263 T/C cg19752551 chr11:57585705 CTNND1 -0.46 -5.98 -0.31 5.62e-9 Blood protein levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00313642 chr3:196014711 PCYT1A 0.43 6.2 0.32 1.58e-9 Lung function (FEV1/FVC); LIHC cis rs1005277 0.579 rs1740732 chr10:38491385 C/T cg17219203 chr10:38645113 HSD17B7P2 -0.4 -5.75 -0.3 1.99e-8 Extrinsic epigenetic age acceleration; LIHC cis rs9399135 1.000 rs4896130 chr6:135355118 C/T cg22676075 chr6:135203613 NA 0.39 6.46 0.33 3.51e-10 Red blood cell count; LIHC cis rs4820294 0.669 rs12628135 chr22:38065655 A/G cg00292662 chr22:38071168 LGALS1 0.38 6.45 0.33 3.82e-10 Fat distribution (HIV); LIHC trans rs4290604 0.679 rs73083545 chr2:237983894 C/G cg15676719 chr1:167598521 RCSD1 0.4 6.26 0.32 1.16e-9 Asthma; LIHC cis rs4975616 0.843 rs4975615 chr5:1315343 C/T cg07493874 chr5:1342172 CLPTM1L 0.53 8.71 0.43 1.31e-16 Lung cancer; LIHC cis rs9902453 0.845 rs62068583 chr17:28001482 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.71 11.51 0.53 4.03e-26 Coffee consumption (cups per day); LIHC cis rs17685 0.753 rs11982200 chr7:75714883 T/C cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs875971 0.964 rs778708 chr7:65856319 T/C cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05063087 chr10:102133314 C10orf75 0.48 6.51 0.33 2.75e-10 Lung function (FEV1/FVC); LIHC trans rs6489882 0.807 rs61266553 chr12:113371977 A/G cg10175203 chr3:128143634 NA 0.38 6.13 0.31 2.41e-9 Chronic lymphocytic leukemia; LIHC cis rs4665809 0.549 rs72809635 chr2:26411674 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.48 6.22 0.32 1.44e-9 Gut microbiome composition (summer); LIHC cis rs4332037 0.664 rs56259105 chr7:1978002 T/C cg23422044 chr7:1970798 MAD1L1 -0.5 -5.97 -0.31 5.95e-9 Bipolar disorder; LIHC cis rs1144333 0.655 rs79322031 chr1:76391978 C/T cg22875332 chr1:76189707 ACADM 0.42 6.3 0.32 9.03e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.67 0.57 1.98e-30 Total body bone mineral density; LIHC cis rs1008375 1.000 rs6849704 chr4:17652031 G/C cg15017067 chr4:17643749 FAM184B 0.34 5.9 0.3 8.54e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7428 0.545 rs4832163 chr2:85541083 T/C cg24342717 chr2:85555507 TGOLN2 -0.76 -10.58 -0.5 8.35e-23 Ear protrusion; LIHC cis rs8017423 0.967 rs2151748 chr14:90694897 G/C cg04374321 chr14:90722782 PSMC1 0.74 14.13 0.61 4.86e-36 Mortality in heart failure; LIHC cis rs1577917 0.958 rs3857480 chr6:86535149 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.75 -0.3 1.96e-8 Response to antipsychotic treatment; LIHC cis rs2599510 0.783 rs62136349 chr2:32827504 G/A cg02381751 chr2:32503542 YIPF4 0.44 5.85 0.3 1.14e-8 Interleukin-18 levels; LIHC cis rs11758351 0.660 rs11755943 chr6:26211368 A/G cg16070018 chr6:26224392 HIST1H3E 0.57 7.01 0.35 1.25e-11 Gout;Renal underexcretion gout; LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg12419862 chr22:24373484 LOC391322 0.6 8.42 0.41 1.01e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2303759 0.874 rs8108669 chr19:49845895 C/T cg22590775 chr19:49891494 CCDC155 0.47 7.83 0.39 6.19e-14 Multiple sclerosis; LIHC cis rs5753037 0.585 rs249401 chr22:30216168 C/T cg01021169 chr22:30184971 ASCC2 -0.42 -8.18 -0.4 5.54e-15 Type 1 diabetes; LIHC cis rs7618915 0.781 rs12489732 chr3:52566820 C/A cg05564831 chr3:52568323 NT5DC2 0.38 6.05 0.31 3.88e-9 Bipolar disorder; LIHC cis rs1256061 0.624 rs944047 chr14:64700292 C/T cg23250157 chr14:64679961 SYNE2 0.4 5.9 0.3 8.74e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7712401 0.818 rs13166350 chr5:122153569 C/T cg18764291 chr5:122110994 SNX2 0.36 6.09 0.31 3.08e-9 Mean platelet volume; LIHC cis rs1059312 0.808 rs10847693 chr12:129292006 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.77 -16.85 -0.67 8.58e-47 Systemic lupus erythematosus; LIHC trans rs11724903 0.935 rs7340820 chr4:183220197 C/T cg16239906 chr20:35724590 RBL1 -0.64 -6.32 -0.32 8.18e-10 Smoking initiation; LIHC cis rs5758659 0.714 rs133376 chr22:42466905 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.41 -7.96 -0.4 2.64e-14 Cognitive function; LIHC cis rs9790314 0.663 rs61105146 chr3:160651949 T/A cg03342759 chr3:160939853 NMD3 0.55 6.5 0.33 2.9e-10 Morning vs. evening chronotype; LIHC cis rs2839186 0.739 rs7282763 chr21:47696800 C/T cg09417038 chr21:47716443 C21orf57 -0.5 -7.29 -0.37 2.12e-12 Testicular germ cell tumor; LIHC cis rs6973256 0.637 rs12539993 chr7:133418799 C/T cg10665199 chr7:133106180 EXOC4 0.34 5.92 0.3 7.79e-9 Intelligence (multi-trait analysis); LIHC cis rs769267 0.929 rs34538000 chr19:19481379 G/T cg26732615 chr19:19648335 CILP2;YJEFN3 -0.39 -5.94 -0.31 6.83e-9 Tonsillectomy; LIHC cis rs769267 0.965 rs12460764 chr19:19431963 G/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.62 -10.08 -0.48 4.34e-21 Tonsillectomy; LIHC cis rs8177253 0.509 rs6762415 chr3:133478557 T/G cg27366882 chr3:133540807 NA -0.38 -7.43 -0.37 8.49e-13 Iron status biomarkers; LIHC cis rs11626933 1.000 rs11626933 chr14:90754311 A/G cg14092571 chr14:90743983 NA -0.9 -14.88 -0.63 5.71e-39 Gut microbiota (bacterial taxa); LIHC cis rs11958404 0.932 rs72816572 chr5:157429818 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.11e-27 IgG glycosylation; LIHC cis rs2070433 0.800 rs11700596 chr21:47874054 G/C cg12379764 chr21:47803548 PCNT 0.7 10.01 0.48 7.7e-21 Lymphocyte counts; LIHC cis rs9303280 0.806 rs34189114 chr17:38032460 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.77 0.3 1.76e-8 Self-reported allergy; LIHC cis rs7666738 0.830 rs28416660 chr4:98899525 C/G cg05340658 chr4:99064831 C4orf37 0.66 11.83 0.54 2.58e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg00149659 chr3:10157352 C3orf10 0.68 7.12 0.36 6.57e-12 Alzheimer's disease; LIHC cis rs9902453 0.845 rs116840018 chr17:28232049 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.61 0.53 1.76e-26 Coffee consumption (cups per day); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27161463 chr11:118123074 MPZL3 0.41 6.17 0.32 1.89e-9 Lung function (FEV1/FVC); LIHC cis rs711245 0.573 rs11899523 chr2:36800918 T/C cg10546459 chr2:36825355 FEZ2 0.49 6.03 0.31 4.31e-9 Height; LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg18306943 chr3:40428807 ENTPD3 -0.44 -7.81 -0.39 6.94e-14 Renal cell carcinoma; LIHC cis rs7542091 0.635 rs7550733 chr1:210044968 G/A cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs10464366 0.544 rs1525799 chr7:39153131 C/G cg18850127 chr7:39170497 POU6F2 -0.46 -8.14 -0.4 7.23e-15 IgG glycosylation; LIHC cis rs57590327 0.528 rs4856346 chr3:81502655 T/G cg07356753 chr3:81810745 GBE1 0.46 6.8 0.35 4.6e-11 Extraversion; LIHC cis rs4808199 0.948 rs2301668 chr19:19452249 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.56 8.12 0.4 8.8e-15 Nonalcoholic fatty liver disease; LIHC cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg21724239 chr8:58056113 NA 0.57 7.11 0.36 6.9e-12 Developmental language disorder (linguistic errors); LIHC cis rs7089973 0.604 rs765173 chr10:116601675 C/T cg23260525 chr10:116636907 FAM160B1 0.39 7.66 0.38 1.94e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9467773 0.596 rs3001369 chr6:26670969 C/T cg09904177 chr6:26538194 HMGN4 0.55 10.94 0.51 4.42e-24 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.966 rs12784482 chr10:35446865 A/G cg03585969 chr10:35415529 CREM 0.87 13.09 0.58 4.92e-32 Inflammatory bowel disease;Crohn's disease; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg04381043 chr16:89341467 ANKRD11 0.39 6.3 0.32 9.33e-10 Bipolar disorder; LIHC cis rs74181299 0.784 rs2723085 chr2:65297359 C/G cg05010058 chr2:65284262 CEP68 0.39 6.54 0.33 2.22e-10 Pulse pressure; LIHC cis rs1395 0.571 rs114507490 chr2:27527246 T/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.47 -6.25 -0.32 1.22e-9 Blood metabolite levels; LIHC trans rs7613875 0.580 rs11709503 chr3:49991167 G/T cg21659725 chr3:3221576 CRBN 0.52 7.61 0.38 2.63e-13 Body mass index; LIHC cis rs11048434 0.761 rs11494570 chr12:9127147 T/C cg04155231 chr12:9217510 LOC144571 0.31 5.8 0.3 1.5e-8 Sjögren's syndrome; LIHC cis rs5769765 0.671 rs138832 chr22:50178082 A/G cg02269571 chr22:50332266 NA -0.56 -7.83 -0.39 6.08e-14 Schizophrenia; LIHC cis rs3806843 1.000 rs3733710 chr5:140167463 C/T cg26395211 chr5:140044315 WDR55 -0.43 -6.43 -0.33 4.28e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs13064411 0.696 rs36054418 chr3:113204762 G/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.25 -0.32 1.21e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs208520 1.000 rs72882102 chr6:66983408 C/A cg07460842 chr6:66804631 NA 0.67 7.3 0.37 2e-12 Exhaled nitric oxide output; LIHC cis rs6963495 0.818 rs818621 chr7:105173029 T/C cg19920283 chr7:105172520 RINT1 0.77 8.62 0.42 2.6e-16 Bipolar disorder (body mass index interaction); LIHC cis rs9902453 1.000 rs4075623 chr17:28386526 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg07424592 chr7:64974309 NA -0.8 -9.28 -0.45 1.99e-18 Diabetic kidney disease; LIHC cis rs921968 0.541 rs933994 chr2:219650616 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.72e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs637571 0.522 rs12792888 chr11:65761446 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.85 0.3 1.13e-8 Eosinophil percentage of white cells; LIHC cis rs9818758 0.556 rs116432667 chr3:48947589 C/T cg00383909 chr3:49044727 WDR6 0.96 7.95 0.4 2.65e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 10.16 0.48 2.26e-21 Platelet count; LIHC cis rs1401999 1.000 rs939337 chr3:183701147 G/C cg01324343 chr3:183735012 ABCC5 0.76 12.8 0.57 6.44e-31 Anterior chamber depth; LIHC cis rs9807989 0.507 rs11465721 chr2:103063240 T/G cg03938978 chr2:103052716 IL18RAP 0.31 6.11 0.31 2.65e-9 Asthma; LIHC cis rs7554547 0.871 rs11588551 chr1:11941936 A/G cg07603449 chr1:11986842 KIAA2013 0.34 5.77 0.3 1.81e-8 Nonsyndromic cleft lip with cleft palate; LIHC cis rs7264396 0.563 rs2425088 chr20:34303902 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC trans rs4714291 1.000 rs847769 chr6:40050171 T/C cg02267698 chr19:7991119 CTXN1 0.38 6.15 0.32 2.15e-9 Strep throat; LIHC trans rs950169 0.512 rs4374136 chr15:84645007 C/G cg24036039 chr1:3397125 ARHGEF16 0.37 6.09 0.31 3.05e-9 Schizophrenia; LIHC cis rs595982 0.527 rs73061659 chr19:49373556 G/A cg21252483 chr19:49399788 TULP2 -0.92 -10.12 -0.48 3.02e-21 Red cell distribution width; LIHC cis rs870825 0.550 rs35981185 chr4:185639720 A/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs7572733 0.534 rs4369854 chr2:198800630 T/C cg00792783 chr2:198669748 PLCL1 0.46 6.86 0.35 3.19e-11 Dermatomyositis; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs3099143 1.000 rs3099134 chr15:77133168 T/G cg21673338 chr15:77095150 SCAPER -0.49 -7.31 -0.37 1.89e-12 Recalcitrant atopic dermatitis; LIHC cis rs1055129 0.682 rs7217432 chr17:73834604 A/G cg10935138 chr17:73851978 WBP2 0.45 6.96 0.35 1.75e-11 White matter hyperintensity burden; LIHC cis rs3960554 1.000 rs2079477 chr7:75836549 C/G cg01364799 chr7:75623366 TMEM120A -0.47 -6.52 -0.33 2.45e-10 Eotaxin levels; LIHC cis rs67311347 0.577 rs1317217 chr3:40271697 T/G cg00656387 chr3:40428638 ENTPD3 0.42 6.74 0.34 6.71e-11 Renal cell carcinoma; LIHC cis rs8044868 0.530 rs2287998 chr16:72059269 C/T cg16558253 chr16:72132732 DHX38 0.37 5.99 0.31 5.46e-9 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs35110281 0.693 rs2838344 chr21:45089877 C/T cg04455712 chr21:45112962 RRP1B 0.53 9.22 0.45 3.12e-18 Mean corpuscular volume; LIHC trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg07870213 chr5:140052090 DND1 1.02 10.41 0.49 3.06e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs72781680 0.752 rs55801864 chr2:23922325 C/T cg08917208 chr2:24149416 ATAD2B 0.98 8.29 0.41 2.61e-15 Lymphocyte counts; LIHC cis rs6750047 0.585 rs4670234 chr2:38272477 C/T cg07380506 chr2:38303506 CYP1B1 0.61 7.89 0.39 4.19e-14 Cutaneous malignant melanoma;Melanoma; LIHC cis rs4803468 0.967 rs284661 chr19:41932120 C/T cg14132834 chr19:41945861 ATP5SL -0.46 -6.71 -0.34 8.26e-11 Height; LIHC cis rs7534824 0.543 rs12568993 chr1:101386259 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.84 0.39 5.72e-14 Refractive astigmatism; LIHC cis rs2795502 0.938 rs2744085 chr10:43341976 C/T cg20628663 chr10:43360327 NA 0.46 7.11 0.36 6.98e-12 Blood protein levels; LIHC cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg19774624 chr17:42201019 HDAC5 -0.83 -12.75 -0.57 9.91e-31 Total body bone mineral density; LIHC cis rs9858542 0.953 rs7646366 chr3:49470668 G/A cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4975616 0.836 rs13178866 chr5:1323212 C/T cg26373071 chr5:1325741 CLPTM1L 0.35 5.73 0.3 2.23e-8 Lung cancer; LIHC cis rs7589728 1.000 rs7589728 chr2:88518440 G/A cg07952391 chr2:88470173 THNSL2 0.66 5.86 0.3 1.1e-8 Plasma clusterin levels; LIHC trans rs61931739 0.500 rs12146843 chr12:34451738 T/G cg26384229 chr12:38710491 ALG10B 0.64 8.13 0.4 8.12e-15 Morning vs. evening chronotype; LIHC cis rs780096 1.000 rs780095 chr2:27741105 A/G cg22903471 chr2:27725779 GCKR -0.32 -5.94 -0.31 6.92e-9 Total body bone mineral density; LIHC cis rs2370759 1.000 rs2769241 chr10:32556229 T/C cg05361325 chr10:32636312 EPC1 0.49 5.99 0.31 5.44e-9 Sexual dysfunction (female); LIHC cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg08888203 chr3:10149979 C3orf24 0.55 6.35 0.32 6.76e-10 Alzheimer's disease; LIHC cis rs6089584 0.627 rs34496616 chr20:60561944 G/A cg06108461 chr20:60628389 TAF4 -0.53 -6.93 -0.35 2.08e-11 Body mass index; LIHC cis rs13108904 0.539 rs13141992 chr4:1340765 C/T cg22903657 chr4:1355424 KIAA1530 -0.43 -6.3 -0.32 9.4e-10 Obesity-related traits; LIHC cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC cis rs1555322 0.530 rs2425047 chr20:33871675 G/T cg03689076 chr20:33865952 NA -0.55 -6.58 -0.34 1.78e-10 Attention deficit hyperactivity disorder; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg04657419 chr5:60454782 C5orf43 -0.27 -6.04 -0.31 3.91e-9 Calcium levels; LIHC cis rs921968 0.541 rs733925 chr2:219302466 G/A cg18887096 chr2:219472410 PLCD4 -0.38 -5.73 -0.3 2.17e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs11098499 0.955 rs13114751 chr4:120156617 G/A cg09307838 chr4:120376055 NA 0.75 10.9 0.51 5.9e-24 Corneal astigmatism; LIHC cis rs4727027 0.901 rs4727017 chr7:148822062 A/G cg23583168 chr7:148888333 NA -0.74 -10.41 -0.49 3.17e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.96 19.34 0.72 8.24e-57 Height; LIHC cis rs6701037 0.748 rs2685 chr1:175127771 A/G cg00321850 chr1:175162397 KIAA0040 0.43 6.97 0.35 1.61e-11 Alcohol dependence; LIHC cis rs6951245 0.744 rs10265758 chr7:1172518 C/T cg18402987 chr7:1209562 NA 0.76 6.11 0.31 2.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15358052 chr14:69865456 SLC39A9;ERH 0.34 6.53 0.33 2.37e-10 Calcium levels; LIHC cis rs3736485 0.966 rs2414109 chr15:51901015 C/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.12 -0.31 2.53e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7945705 0.935 rs10769971 chr11:8925276 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.06 0.36 9.23e-12 Hemoglobin concentration; LIHC cis rs1943345 0.686 rs10898088 chr11:82874970 G/A cg07047830 chr11:82868014 PCF11 0.53 9.23 0.45 2.83e-18 Obesity-related traits; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg10590909 chr10:70286987 SLC25A16 -0.45 -6.23 -0.32 1.38e-9 Lung cancer in ever smokers; LIHC cis rs1577917 0.958 rs10944137 chr6:86454314 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.27 -0.37 2.41e-12 Response to antipsychotic treatment; LIHC cis rs11718455 0.960 rs13065591 chr3:43996585 T/C cg08738300 chr3:44038990 NA 0.53 9.14 0.44 5.57e-18 Coronary artery disease; LIHC cis rs4819052 0.851 rs28616694 chr21:46674786 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.86 0.39 5.05e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6502050 0.805 rs62080003 chr17:80078957 C/T cg11859384 chr17:80120422 CCDC57 0.43 5.85 0.3 1.14e-8 Life satisfaction; LIHC cis rs60871478 0.947 rs7790823 chr7:788923 T/G cg04727924 chr7:799746 HEATR2 -0.61 -8.98 -0.44 1.9e-17 Cerebrospinal P-tau181p levels; LIHC cis rs1005277 0.579 rs9418322 chr10:38377296 G/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC trans rs7668874 0.779 rs4604123 chr4:116750790 T/C cg08917878 chr5:172668965 NA -0.3 -6.05 -0.31 3.89e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs1401999 1.000 rs6804242 chr3:183659463 A/T cg05044414 chr3:183734942 ABCC5 0.35 6.22 0.32 1.49e-9 Anterior chamber depth; LIHC cis rs8084351 0.577 rs4939723 chr18:50673089 G/A cg24270629 chr18:50823537 DCC -0.44 -6.54 -0.33 2.18e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs16854884 0.586 rs4527375 chr3:143735515 A/T cg06585982 chr3:143692056 C3orf58 -0.56 -7.27 -0.37 2.51e-12 Economic and political preferences (feminism/equality); LIHC cis rs12477438 0.520 rs4851187 chr2:99745860 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.84 -15.08 -0.63 9.66e-40 Chronic sinus infection; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07573366 chr7:32802765 NA 0.28 6.6 0.34 1.54e-10 Longevity; LIHC cis rs11233413 1.000 rs7106216 chr11:82712618 A/G cg24227371 chr11:82718527 RAB30 -0.33 -7.16 -0.36 4.96e-12 Economic and political preferences (feminism/equality); LIHC cis rs2421770 0.530 rs4756217 chr11:35366733 C/T cg13971030 chr11:35366721 SLC1A2 -0.45 -7.6 -0.38 2.95e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs8180040 0.726 rs2385867 chr3:47059323 C/T cg27129171 chr3:47204927 SETD2 0.67 12.0 0.54 6.22e-28 Colorectal cancer; LIHC cis rs3770081 0.536 rs7562837 chr2:86306251 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.96 -12.72 -0.57 1.29e-30 Facial emotion recognition (sad faces); LIHC cis rs3008870 0.755 rs2815380 chr1:67510857 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.51 -8.98 -0.44 1.82e-17 Lymphocyte percentage of white cells; LIHC cis rs7208859 0.573 rs56031503 chr17:29075665 T/C cg14067834 chr17:29058358 SUZ12P 0.71 7.09 0.36 7.5e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs765787 0.530 rs55771002 chr15:45541566 T/C cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC cis rs11626933 1.000 rs11626016 chr14:90747979 C/T cg14092571 chr14:90743983 NA -0.9 -14.86 -0.63 6.84e-39 Gut microbiota (bacterial taxa); LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg02475777 chr4:1388615 CRIPAK 0.55 8.13 0.4 8.15e-15 Longevity; LIHC cis rs6788895 1.000 rs7636866 chr3:150461568 A/T cg07663535 chr3:150480033 SIAH2 0.52 6.37 0.33 6.08e-10 Breast cancer; LIHC cis rs751728 1.000 rs943477 chr6:33750931 T/C cg25922239 chr6:33757077 LEMD2 0.44 7.37 0.37 1.32e-12 Crohn's disease; LIHC cis rs4853525 0.522 rs6744420 chr2:191589082 A/G cg05765582 chr2:191677683 NA -0.3 -5.89 -0.3 9.07e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs12594515 0.967 rs11857628 chr15:45998206 C/T cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.68e-18 Waist circumference;Weight; LIHC cis rs1691799 0.899 rs1168329 chr12:66731864 C/A cg16791601 chr12:66731901 HELB -0.57 -14.08 -0.61 7.81e-36 White blood cell count (basophil); LIHC cis rs9942416 0.630 rs253388 chr5:74975912 A/G cg00601450 chr5:74908170 NA -0.48 -6.84 -0.35 3.62e-11 Age-related disease endophenotypes; LIHC cis rs1865760 0.927 rs6915834 chr6:25935427 A/C cg12310025 chr6:25882481 NA -0.42 -6.32 -0.32 8.09e-10 Height; LIHC cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg12792011 chr19:58661915 ZNF329 0.95 7.77 0.39 9.44e-14 Cholesterol, total; LIHC trans rs2363709 1.000 rs7620108 chr3:67423817 A/G cg15775005 chr18:9136598 ANKRD12 -0.81 -6.07 -0.31 3.33e-9 IgE levels; LIHC cis rs1865760 0.566 rs1800702 chr6:26086463 C/G cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs28655083 0.828 rs7404322 chr16:77130003 G/A cg01753188 chr16:77233325 SYCE1L;MON1B 0.44 6.86 0.35 3.21e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg27170947 chr2:26402098 FAM59B 0.66 8.34 0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg18252515 chr7:66147081 NA -1.3 -16.62 -0.67 6.84e-46 Diabetic kidney disease; LIHC cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs10213084 1.000 rs7671823 chr4:147497707 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs12701220 0.901 rs12701713 chr7:1090505 G/A cg00990874 chr7:1149470 C7orf50 -0.66 -9.44 -0.45 5.77e-19 Bronchopulmonary dysplasia; LIHC cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.82 0.51 1.15e-23 Colorectal cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26155979 chr10:105110866 PCGF6 -0.47 -6.27 -0.32 1.07e-9 Hepatitis; LIHC cis rs2273156 1.000 rs8017191 chr14:35469991 G/A cg16230307 chr14:35515116 FAM177A1 -0.41 -6.05 -0.31 3.88e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs7592578 0.640 rs56127319 chr2:191296429 G/A cg10560079 chr2:191398806 TMEM194B -0.78 -11.26 -0.52 3.07e-25 Diastolic blood pressure; LIHC cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.1e-51 Menopause (age at onset); LIHC cis rs1577917 1.000 rs1337844 chr6:86677273 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.55 -0.33 2.08e-10 Response to antipsychotic treatment; LIHC cis rs6582630 0.638 rs12231073 chr12:38526901 T/G cg26384229 chr12:38710491 ALG10B -0.49 -6.85 -0.35 3.49e-11 Drug-induced liver injury (flucloxacillin); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26856583 chr16:87425887 MAP1LC3B;FBXO31 0.43 6.19 0.32 1.76e-9 Pancreatic cancer; LIHC cis rs7044106 0.762 rs10739570 chr9:123381222 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.6 0.38 2.88e-13 Hip circumference adjusted for BMI; LIHC cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg13271783 chr10:134563150 INPP5A -0.54 -6.61 -0.34 1.47e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07627390 chr16:23652638 PALB2;DCTN5 -0.47 -6.97 -0.35 1.61e-11 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19916637 chr8:95961757 TP53INP1 -0.47 -7.11 -0.36 6.8e-12 Pancreatic cancer; LIHC cis rs734999 0.588 rs2764848 chr1:2530694 G/A cg18854424 chr1:2615690 NA -0.33 -7.27 -0.37 2.5e-12 Ulcerative colitis; LIHC cis rs1707322 0.685 rs28617418 chr1:46189526 T/A cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs853679 0.517 rs9366715 chr6:28064633 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs116095464 0.558 rs59284383 chr5:284525 C/G cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs66887589 0.592 rs62320740 chr4:120279486 C/A cg09307838 chr4:120376055 NA 0.53 8.06 0.4 1.3e-14 Diastolic blood pressure; LIHC cis rs1949733 0.816 rs2631746 chr4:8490934 C/T cg11789530 chr4:8429930 ACOX3 -0.72 -10.89 -0.51 6.35e-24 Response to antineoplastic agents; LIHC cis rs7712401 0.623 rs922140 chr5:122088890 A/G cg18764291 chr5:122110994 SNX2 0.39 6.52 0.33 2.47e-10 Mean platelet volume; LIHC cis rs826838 0.935 rs11169547 chr12:39185625 C/A cg26384229 chr12:38710491 ALG10B 0.85 11.0 0.51 2.59e-24 Heart rate; LIHC cis rs6541297 1.000 rs6658942 chr1:230287517 A/C cg20703242 chr1:230279135 GALNT2 0.35 6.51 0.33 2.67e-10 Coronary artery disease; LIHC cis rs10540 0.818 rs12806089 chr11:501468 G/A cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.78e-15 Body mass index; LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg10217327 chr6:118973057 C6orf204 -0.67 -6.63 -0.34 1.29e-10 Diastolic blood pressure; LIHC cis rs7772486 0.624 rs6930154 chr6:146025662 C/T cg13319975 chr6:146136371 FBXO30 0.38 6.34 0.32 7.33e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2304069 0.954 rs2340463 chr5:149409294 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 1.0 12.77 0.57 8.55e-31 HIV-1 control; LIHC cis rs1005277 0.579 rs116912400 chr10:38479207 G/T cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.28 -0.32 1.02e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.846 rs2030416 chr12:38465118 A/G cg13010199 chr12:38710504 ALG10B -0.42 -5.88 -0.3 9.83e-9 Bladder cancer; LIHC cis rs6963495 0.818 rs73192144 chr7:105203535 C/T cg19920283 chr7:105172520 RINT1 0.64 5.8 0.3 1.55e-8 Bipolar disorder (body mass index interaction); LIHC cis rs3789045 0.729 rs61817460 chr1:204543579 G/A cg17419461 chr1:204415978 PIK3C2B -0.44 -6.78 -0.34 5.31e-11 Educational attainment (college completion); LIHC cis rs2070488 1.000 rs13058903 chr3:38513365 C/T cg24069376 chr3:38537580 EXOG -0.41 -7.75 -0.39 1.03e-13 Electrocardiographic conduction measures; LIHC cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs6570726 0.599 rs9376951 chr6:145898911 C/T cg05347473 chr6:146136440 FBXO30 0.43 6.19 0.32 1.76e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9309711 0.666 rs6767 chr2:3483205 C/T cg15506890 chr2:3487001 NA -0.47 -7.55 -0.38 3.9e-13 Neurofibrillary tangles; LIHC cis rs2758596 1.000 rs2758596 chr1:156189286 C/T cg24450063 chr1:156163899 SLC25A44 1.0 10.5 0.49 1.49e-22 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs7772486 0.875 rs2748483 chr6:146335560 A/T cg23711669 chr6:146136114 FBXO30 -0.6 -10.61 -0.5 6.15e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs3768617 0.510 rs10797852 chr1:183101302 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg07677032 chr17:61819896 STRADA 0.44 6.42 0.33 4.45e-10 Prudent dietary pattern; LIHC cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg08280861 chr8:58055591 NA 0.54 7.89 0.39 4e-14 Developmental language disorder (linguistic errors); LIHC cis rs10028773 0.700 rs7671797 chr4:120248157 A/G cg09307838 chr4:120376055 NA 0.71 11.2 0.52 5.31e-25 Educational attainment; LIHC cis rs2281845 0.826 rs4915214 chr1:201076290 T/A cg24849736 chr1:201084428 NA -0.33 -5.93 -0.31 7.59e-9 Permanent tooth development; LIHC cis rs6504950 0.679 rs9908752 chr17:52983216 C/T cg10237252 chr17:52977213 TOM1L1 -0.36 -6.31 -0.32 8.86e-10 Breast cancer; LIHC cis rs10540 1.000 rs35068485 chr11:466032 A/T cg03576123 chr11:487126 PTDSS2 -1.0 -8.14 -0.4 7.3e-15 Body mass index; LIHC cis rs17685 0.672 rs55807301 chr7:75807401 C/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.32 -0.32 7.93e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg09367891 chr1:107599246 PRMT6 -0.68 -11.2 -0.52 5.01e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7726839 0.540 rs72705030 chr5:645562 C/T cg09021430 chr5:549028 NA -0.42 -8.49 -0.42 6.34e-16 Obesity-related traits; LIHC cis rs920590 0.642 rs6993525 chr8:19671104 A/G cg03894339 chr8:19674705 INTS10 -0.58 -9.41 -0.45 7.53e-19 Acute lymphoblastic leukemia (childhood); LIHC cis rs35110281 0.714 rs2282526 chr21:45080552 A/T cg21573476 chr21:45109991 RRP1B -0.6 -11.29 -0.52 2.54e-25 Mean corpuscular volume; LIHC cis rs9394841 0.692 rs9369312 chr6:41841535 A/T cg08135965 chr6:41755394 TOMM6 0.45 6.03 0.31 4.14e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs9381040 0.674 rs3747742 chr6:41162518 C/T cg25110423 chr6:41068646 NFYA;LOC221442 0.37 6.2 0.32 1.66e-9 Alzheimer's disease (late onset); LIHC trans rs11148252 0.840 rs3886077 chr13:52949053 C/A cg18335740 chr13:41363409 SLC25A15 0.38 6.64 0.34 1.21e-10 Lewy body disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13938963 chr4:68411314 CENPC1 0.47 6.74 0.34 6.63e-11 Lung function (FEV1/FVC); LIHC cis rs59698941 0.943 rs59634464 chr5:132178735 A/G cg02081065 chr5:132209139 LEAP2 0.3 6.38 0.33 5.75e-10 Apolipoprotein A-IV levels; LIHC cis rs2066819 1.000 rs2643623 chr12:56689725 G/C cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Psoriasis vulgaris; LIHC cis rs4919087 0.748 rs701810 chr10:98974849 C/T cg25902810 chr10:99078978 FRAT1 -0.54 -6.25 -0.32 1.22e-9 Monocyte count; LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs4908768 1.000 rs12134896 chr1:8656227 G/A cg20416874 chr1:8611966 RERE 0.55 7.17 0.36 4.69e-12 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg18654377 chr3:49208889 KLHDC8B -0.51 -6.06 -0.31 3.58e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs1003719 0.788 rs4572679 chr21:38453227 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 12.12 0.55 2.33e-28 Eye color traits; LIHC cis rs2404602 0.684 rs11072600 chr15:76867915 T/C cg23625390 chr15:77176239 SCAPER -0.54 -8.96 -0.44 2.11e-17 Blood metabolite levels; LIHC cis rs1949733 0.675 rs2688219 chr4:8444631 T/C cg11789530 chr4:8429930 ACOX3 0.75 10.99 0.51 2.96e-24 Response to antineoplastic agents; LIHC cis rs950169 0.544 rs2036949 chr15:85163605 T/C cg17507749 chr15:85114479 UBE2QP1 0.7 8.04 0.4 1.44e-14 Schizophrenia; LIHC cis rs1395 0.778 rs17005956 chr2:27451099 C/T cg23587288 chr2:27483067 SLC30A3 -0.35 -6.47 -0.33 3.34e-10 Blood metabolite levels; LIHC cis rs12908161 1.000 rs62021219 chr15:85256159 C/T cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.42 0.62 3.58e-37 Prudent dietary pattern; LIHC cis rs2067615 0.579 rs66716938 chr12:107196825 T/C cg15890332 chr12:107067104 RFX4 0.26 6.09 0.31 3.08e-9 Heart rate; LIHC cis rs1401999 0.898 rs9876143 chr3:183731362 C/G cg20387954 chr3:183756860 HTR3D 0.29 6.17 0.32 1.95e-9 Anterior chamber depth; LIHC cis rs12477438 0.715 rs6724476 chr2:99627316 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.26 -0.41 3.31e-15 Chronic sinus infection; LIHC cis rs10744422 1.000 rs2292134 chr12:123334033 C/G cg18912006 chr12:123335444 HIP1R -0.63 -7.64 -0.38 2.14e-13 Schizophrenia; LIHC cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg25894440 chr7:65020034 NA 0.51 5.9 0.3 8.83e-9 Diabetic kidney disease; LIHC cis rs4713118 0.513 rs149951 chr6:28033087 T/C cg23485639 chr6:28045615 ZNF165 0.38 5.77 0.3 1.75e-8 Parkinson's disease; LIHC cis rs2303759 0.918 rs7251704 chr19:49890873 T/G cg22307029 chr19:49891270 CCDC155 0.58 9.25 0.45 2.4e-18 Multiple sclerosis; LIHC cis rs7659604 0.540 rs11934307 chr4:122677514 G/A cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.51e-11 Type 2 diabetes; LIHC cis rs35110281 0.805 rs2838319 chr21:44991901 A/G cg04455712 chr21:45112962 RRP1B 0.45 7.79 0.39 8.32e-14 Mean corpuscular volume; LIHC cis rs904251 0.797 rs1757181 chr6:37485728 A/G cg08126542 chr6:37504118 NA 0.41 6.65 0.34 1.18e-10 Cognitive performance; LIHC cis rs4713118 0.629 rs172165 chr6:28020814 T/G cg16479474 chr6:28041457 NA 0.47 7.15 0.36 5.22e-12 Parkinson's disease; LIHC cis rs17685 0.558 rs60787921 chr7:75792844 C/A cg16684958 chr7:75615977 POR 0.52 8.59 0.42 3.22e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2573652 0.722 rs12908133 chr15:100544405 G/A cg09918751 chr15:100517450 ADAMTS17 -0.71 -12.27 -0.55 6.53e-29 Height; LIHC cis rs992157 0.764 rs4552182 chr2:219184872 G/T cg00012203 chr2:219082015 ARPC2 0.76 10.74 0.5 2.16e-23 Colorectal cancer; LIHC cis rs7772486 0.754 rs9373476 chr6:146139741 C/G cg05347473 chr6:146136440 FBXO30 0.36 5.89 0.3 9.41e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12477438 0.520 rs6712704 chr2:99719687 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.53 0.64 1.5e-41 Chronic sinus infection; LIHC cis rs12971120 0.891 rs4891558 chr18:72170359 A/G cg25817165 chr18:72167213 CNDP2 -0.72 -12.41 -0.56 1.96e-29 Refractive error; LIHC cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.73 -0.3 2.25e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4888262 0.526 rs7191754 chr16:74610850 G/T cg01733217 chr16:74700730 RFWD3 0.82 16.24 0.66 2.33e-44 Testicular germ cell tumor; LIHC cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.04 -10.69 -0.5 3.39e-23 Platelet count; LIHC cis rs3806843 0.706 rs2563302 chr5:140079051 T/C cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2841277 0.708 rs2582533 chr14:105398787 G/C cg21017887 chr14:105400489 NA 0.67 12.32 0.55 4.03e-29 Rheumatoid arthritis; LIHC cis rs12477438 0.520 rs11123761 chr2:99705903 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 13.23 0.58 1.43e-32 Chronic sinus infection; LIHC cis rs5769765 0.671 rs138833 chr22:50178917 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.53 -6.53 -0.33 2.37e-10 Schizophrenia; LIHC cis rs7615952 0.641 rs7632497 chr3:125783086 A/C cg05084668 chr3:125655381 ALG1L -0.39 -6.01 -0.31 4.66e-9 Blood pressure (smoking interaction); LIHC cis rs4908760 0.864 rs6701331 chr1:8670206 A/C cg20416874 chr1:8611966 RERE -0.64 -12.41 -0.56 1.83e-29 Vitiligo; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg23131131 chr22:24373011 LOC391322 -0.73 -11.04 -0.51 1.88e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9914988 0.943 rs7224870 chr17:27102620 A/G cg20469991 chr17:27169893 C17orf63 -0.49 -6.03 -0.31 4.35e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs3096299 0.900 rs4785663 chr16:89434888 G/A cg08822215 chr16:89438651 ANKRD11 -0.46 -7.23 -0.36 3.15e-12 Multiple myeloma (IgH translocation); LIHC cis rs7647973 1.000 rs6783003 chr3:49524778 G/C cg07636037 chr3:49044803 WDR6 -0.53 -6.46 -0.33 3.52e-10 Menarche (age at onset); LIHC cis rs6088590 1.000 rs6058111 chr20:33310999 T/C cg06115741 chr20:33292138 TP53INP2 0.6 8.57 0.42 3.68e-16 Coronary artery disease; LIHC cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg12463550 chr7:65579703 CRCP 0.66 6.92 0.35 2.23e-11 Diabetic kidney disease; LIHC trans rs1075232 1.000 rs72722861 chr15:31704288 G/A cg17859187 chr1:168147929 TIPRL 0.75 6.04 0.31 3.96e-9 Survival in colorectal cancer (non-distant metastatic); LIHC trans rs6489882 0.867 rs10850098 chr12:113362058 C/G cg10175203 chr3:128143634 NA 0.39 6.39 0.33 5.5e-10 Chronic lymphocytic leukemia; LIHC cis rs7786877 0.723 rs73407376 chr7:100215200 C/T cg00334542 chr7:100209784 MOSPD3 -0.73 -7.78 -0.39 8.39e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12594515 1.000 rs11070467 chr15:45985001 C/T cg19682013 chr15:45996608 NA -0.4 -7.11 -0.36 6.73e-12 Waist circumference;Weight; LIHC cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg08132940 chr7:1081526 C7orf50 -0.83 -6.87 -0.35 3.01e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs11165623 0.715 rs1980769 chr1:96888201 A/T cg10631902 chr5:14652156 NA -0.33 -8.42 -0.41 1.01e-15 Hip circumference;Waist circumference; LIHC cis rs4721295 0.573 rs3779000 chr7:2181628 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.81 -0.3 1.41e-8 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs57590327 0.508 rs7621968 chr3:81951460 A/G cg07356753 chr3:81810745 GBE1 -0.52 -8.15 -0.4 6.8e-15 Extraversion; LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs7927771 0.524 rs10838784 chr11:47882341 G/A cg20307385 chr11:47447363 PSMC3 0.73 10.79 0.5 1.43e-23 Subjective well-being; LIHC cis rs28489187 0.706 rs66811655 chr1:85831544 T/G cg16011679 chr1:85725395 C1orf52 0.45 5.71 0.3 2.44e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs7131987 0.903 rs10843371 chr12:29414232 G/A cg16970926 chr12:29381810 FAR2 0.29 6.1 0.31 2.81e-9 QT interval; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08134106 chr19:57999036 ZNF419 -0.54 -6.18 -0.32 1.79e-9 Systolic blood pressure; LIHC cis rs986417 1.000 rs986417 chr14:60858761 C/T cg27398547 chr14:60952738 C14orf39 -0.65 -7.93 -0.39 3.15e-14 Gut microbiota (bacterial taxa); LIHC cis rs2637266 0.935 rs7393727 chr10:78365977 T/A cg18941641 chr10:78392320 NA 0.3 6.5 0.33 2.92e-10 Pulmonary function; LIHC cis rs909002 0.759 rs10914454 chr1:32078940 G/A cg13919466 chr1:32135498 COL16A1 -0.35 -6.58 -0.34 1.74e-10 Intelligence (multi-trait analysis); LIHC cis rs2236918 0.710 rs1776130 chr1:242023362 A/G cg17736920 chr1:242011382 EXO1 0.41 6.09 0.31 2.98e-9 Menopause (age at onset); LIHC cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs6459788 0.934 rs10251462 chr7:157258183 C/G cg06271696 chr7:157225062 NA -0.37 -6.52 -0.33 2.54e-10 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs9733 0.650 rs9803935 chr1:150552622 T/G cg13175981 chr1:150552382 MCL1 0.61 9.51 0.46 3.62e-19 Tonsillectomy; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg19635926 chr16:89946313 TCF25 0.57 7.56 0.38 3.82e-13 Skin colour saturation; LIHC cis rs194045 0.511 rs1611991 chr16:29151593 C/T cg16691023 chr16:29205632 NA -0.49 -6.55 -0.33 2.13e-10 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg09033563 chr22:24373618 LOC391322 -0.48 -6.78 -0.34 5.31e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs2727020 0.658 rs4980440 chr11:49386017 C/T cg18944383 chr4:111397179 ENPEP 0.26 6.38 0.33 5.72e-10 Coronary artery disease; LIHC cis rs801193 0.569 rs2013908 chr7:66121069 A/T cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg11764359 chr7:65958608 NA -0.58 -5.98 -0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs16828019 0.789 rs36084778 chr1:41479538 A/G cg03387723 chr1:41708464 SCMH1 -0.42 -6.7 -0.34 8.55e-11 Intelligence (multi-trait analysis); LIHC cis rs11711311 1.000 rs9827682 chr3:113450251 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.25 0.41 3.56e-15 IgG glycosylation; LIHC cis rs72627123 0.867 rs58102735 chr14:74467531 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.63 0.42 2.42e-16 Morning vs. evening chronotype; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg22535921 chr3:58419709 PDHB 0.6 7.47 0.37 6.55e-13 Hepatitis; LIHC cis rs748404 0.601 rs489964 chr15:43517554 G/A cg27015174 chr15:43622946 ADAL;LCMT2 -0.36 -5.99 -0.31 5.25e-9 Lung cancer; LIHC cis rs17345786 0.906 rs72946021 chr3:101250008 T/G cg11279151 chr3:101281821 RG9MTD1 -0.45 -6.11 -0.31 2.74e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs6466055 0.720 rs1204077 chr7:104984019 T/C cg04380332 chr7:105027541 SRPK2 0.37 6.91 0.35 2.32e-11 Schizophrenia; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg00280220 chr17:61926910 NA 0.44 7.12 0.36 6.29e-12 Prudent dietary pattern; LIHC cis rs7044106 0.762 rs10760107 chr9:123383630 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.05 0.51 1.78e-24 Hip circumference adjusted for BMI; LIHC cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg25894440 chr7:65020034 NA -0.45 -5.79 -0.3 1.6e-8 Diabetic kidney disease; LIHC cis rs28735056 1.000 rs56197868 chr18:77636077 C/T cg20368463 chr18:77673604 PQLC1 -0.34 -5.79 -0.3 1.6e-8 Schizophrenia; LIHC cis rs7312774 0.618 rs7953088 chr12:107334539 G/C cg16260113 chr12:107380972 MTERFD3 0.85 10.88 0.51 7.23e-24 Severe influenza A (H1N1) infection; LIHC cis rs7772486 0.875 rs2777477 chr6:146305491 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.84 -0.3 1.2e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs910316 0.737 rs175045 chr14:75475275 A/C cg00929392 chr1:19283191 IFFO2 -0.45 -6.09 -0.31 3.09e-9 Height; LIHC cis rs6831352 0.918 rs4699713 chr4:100060513 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs11018874 0.597 rs4393275 chr11:89886397 C/T cg05041596 chr11:89867385 NAALAD2 0.43 7.54 0.38 4.23e-13 White blood cell types; LIHC trans rs1973993 0.507 rs2759670 chr1:97002864 A/G cg10631902 chr5:14652156 NA 0.32 7.5 0.38 5.5e-13 Weight; LIHC cis rs1707322 0.721 rs12043945 chr1:46106922 T/A cg06784218 chr1:46089804 CCDC17 0.42 7.87 0.39 4.71e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7937890 0.559 rs2575830 chr11:14485602 C/A cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg03264133 chr6:25882463 NA -0.71 -9.21 -0.45 3.42e-18 Intelligence (multi-trait analysis); LIHC cis rs6942756 1.000 rs13235749 chr7:128879678 C/G cg02491457 chr7:128862824 NA -0.73 -11.49 -0.53 4.78e-26 White matter hyperintensity burden; LIHC cis rs12291225 0.679 rs4756786 chr11:14285900 C/A cg19336497 chr11:14380999 RRAS2 -0.64 -12.8 -0.57 6.41e-31 Sense of smell; LIHC cis rs10870270 1.000 rs10870292 chr10:133770782 G/C cg26149184 chr10:133730230 NA 0.48 7.51 0.38 5.25e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg11648662 chr10:69524272 NA 0.33 6.08 0.31 3.2e-9 Calcium levels; LIHC cis rs12472274 0.941 rs4663861 chr2:239105203 C/T cg17459225 chr2:239074497 NA 0.78 12.95 0.57 1.68e-31 Phospholipid levels (plasma); LIHC cis rs600806 0.850 rs6537757 chr1:109936682 G/A cg16275483 chr1:110013120 SYPL2 -0.47 -5.92 -0.3 7.87e-9 Intelligence (multi-trait analysis); LIHC cis rs77861329 1.000 rs352150 chr3:52209995 A/G cg08692210 chr3:52188851 WDR51A 0.84 8.06 0.4 1.32e-14 Macrophage inflammatory protein 1b levels; LIHC trans rs208520 0.690 rs1100981 chr6:66852052 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.73 -8.22 -0.41 4.3e-15 Exhaled nitric oxide output; LIHC cis rs807669 0.548 rs762522 chr22:19180575 C/T cg02655711 chr22:19163373 SLC25A1 0.35 6.12 0.31 2.57e-9 Metabolite levels; LIHC cis rs798554 0.797 rs798494 chr7:2798294 C/A cg04166393 chr7:2884313 GNA12 0.44 6.19 0.32 1.71e-9 Height; LIHC cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs11958404 0.615 rs7717217 chr5:157447749 C/T cg05962755 chr5:157440814 NA 0.59 7.83 0.39 6.15e-14 IgG glycosylation; LIHC cis rs7945718 0.840 rs10741601 chr11:12735873 T/C cg25843174 chr11:12811716 TEAD1 0.3 6.86 0.35 3.34e-11 Educational attainment (years of education); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19970425 chr15:55581976 RAB27A 0.4 6.24 0.32 1.28e-9 Calcium levels; LIHC cis rs17106184 0.901 rs59600829 chr1:51405667 C/T cg07174182 chr1:51127561 FAF1 -0.75 -7.9 -0.39 3.96e-14 Type 2 diabetes; LIHC cis rs4819052 0.851 rs8131143 chr21:46671646 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.56 -8.01 -0.4 1.84e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12500138 1.000 rs72995997 chr4:166215850 G/A cg25064052 chr4:166216151 KLHL2 -0.61 -5.77 -0.3 1.8e-8 Cognitive function; LIHC cis rs1580019 0.563 rs764483 chr7:32578150 A/T cg14728415 chr7:32535168 LSM5;AVL9 0.41 5.83 0.3 1.3e-8 Cognitive ability; LIHC cis rs896854 0.738 rs509594 chr8:95967156 C/G cg13393036 chr8:95962371 TP53INP1 0.39 8.03 0.4 1.54e-14 Type 2 diabetes; LIHC cis rs10493773 0.510 rs11161645 chr1:86092872 T/C cg17807903 chr1:86174739 ZNHIT6 0.49 8.75 0.43 9.76e-17 Urate levels in overweight individuals; LIHC cis rs6121246 0.908 rs17093657 chr20:30428894 G/A cg13852791 chr20:30311386 BCL2L1 0.86 9.05 0.44 1.12e-17 Mean corpuscular hemoglobin; LIHC cis rs9733 0.596 rs6669369 chr1:150695892 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21702128 chr5:142784721 NR3C1 0.44 6.31 0.32 8.47e-10 Pancreatic cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21487267 chr8:41386754 GINS4 -0.52 -6.5 -0.33 2.83e-10 Systolic blood pressure; LIHC cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg03806693 chr22:41940476 POLR3H 1.08 12.77 0.57 8.03e-31 Vitiligo; LIHC cis rs8060686 0.516 rs8048365 chr16:68253326 T/A cg05110241 chr16:68378359 PRMT7 -0.51 -6.07 -0.31 3.45e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs11122272 0.735 rs973252 chr1:231520802 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs921968 0.541 rs4674310 chr2:219318078 T/C cg02176678 chr2:219576539 TTLL4 -0.57 -8.03 -0.4 1.59e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs4820539 1.000 rs5759596 chr22:23475750 G/A cg21100191 chr22:23484243 RTDR1 0.91 17.11 0.68 7.42e-48 Bone mineral density; LIHC cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg23758822 chr17:41437982 NA 0.94 17.56 0.69 1.21e-49 Menopause (age at onset); LIHC cis rs6684514 0.845 rs12138564 chr1:156291600 G/T cg16558208 chr1:156270281 VHLL 0.54 10.25 0.48 1.12e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7552404 1.000 rs11163924 chr1:76132070 A/C cg10523679 chr1:76189770 ACADM -0.63 -8.76 -0.43 9.31e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg10755058 chr3:40428713 ENTPD3 0.42 7.14 0.36 5.46e-12 Renal cell carcinoma; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05590233 chr17:109545 RPH3AL 0.42 6.05 0.31 3.91e-9 Longevity; LIHC cis rs992157 0.798 rs4674284 chr2:219161241 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.76 -11.98 -0.54 7.57e-28 Colorectal cancer; LIHC cis rs11644362 1.000 rs4781349 chr16:12987249 T/C cg06890432 chr16:12997467 SHISA9 -0.4 -6.77 -0.34 5.57e-11 Positive affect;Subjective well-being; LIHC cis rs1691799 0.899 rs1168292 chr12:66732660 C/T cg16791601 chr12:66731901 HELB -0.56 -13.79 -0.6 1.05e-34 White blood cell count (basophil); LIHC cis rs7116495 1.000 rs2186637 chr11:71570115 C/T cg26138937 chr11:71823887 C11orf51 0.68 6.63 0.34 1.3100000000000001e-10 Severe influenza A (H1N1) infection; LIHC cis rs17253792 0.822 rs112374071 chr14:56061919 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.25 -0.41 3.35e-15 Putamen volume; LIHC cis rs60871478 1.000 rs62432251 chr7:801855 T/G cg13844804 chr7:814759 HEATR2 0.44 5.94 0.31 6.96e-9 Cerebrospinal P-tau181p levels; LIHC cis rs600806 0.850 rs10858091 chr1:109935578 T/C cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs2455799 0.519 rs2062821 chr3:15697644 A/T cg12698662 chr3:15914712 MIR563 -0.39 -7.15 -0.36 5.32e-12 Mean platelet volume; LIHC cis rs57590327 0.504 rs13065281 chr3:81693550 G/A cg07356753 chr3:81810745 GBE1 -0.55 -8.33 -0.41 1.92e-15 Extraversion; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.6 8.64 0.42 2.24e-16 Lymphocyte counts; LIHC cis rs2108622 0.727 rs8102532 chr19:15980060 G/A cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs28374715 0.662 rs28827035 chr15:41492290 G/A cg18705301 chr15:41695430 NDUFAF1 -0.88 -9.72 -0.47 7.19e-20 Ulcerative colitis; LIHC cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg09222892 chr1:25734099 RHCE -0.47 -8.85 -0.43 4.7e-17 Erythrocyte sedimentation rate; LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg11494091 chr17:61959527 GH2 0.44 8.1 0.4 9.71e-15 Prudent dietary pattern; LIHC cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.33 0.45 1.38e-18 Bipolar disorder; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg06873352 chr17:61820015 STRADA 0.75 13.58 0.59 6.97e-34 Prudent dietary pattern; LIHC cis rs12464559 0.649 rs4393745 chr2:152594206 G/T cg01189475 chr2:152685088 ARL5A 0.7 7.91 0.39 3.58e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs6951245 0.832 rs10266519 chr7:1142977 C/T cg18402987 chr7:1209562 NA 0.77 5.74 0.3 2.05e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg21724239 chr8:58056113 NA 0.6 7.73 0.39 1.2e-13 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.953 rs35693858 chr10:979813 C/T cg26597838 chr10:835615 NA 0.96 10.83 0.51 1.06e-23 Eosinophil percentage of granulocytes; LIHC cis rs1144333 0.655 rs1146602 chr1:76239309 A/G cg22875332 chr1:76189707 ACADM -0.44 -6.46 -0.33 3.56e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs703842 0.616 rs10783850 chr12:58229377 T/C cg18357645 chr12:58087776 OS9 -0.41 -5.93 -0.31 7.46e-9 Multiple sclerosis; LIHC cis rs2732480 0.577 rs1489109 chr12:48738780 C/A cg21466736 chr12:48725269 NA -0.72 -10.85 -0.51 8.84e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.69 -0.34 9.38e-11 Total body bone mineral density; LIHC cis rs67311347 0.911 rs6773917 chr3:40469254 G/T cg24209194 chr3:40518798 ZNF619 0.49 7.23 0.36 3.17e-12 Renal cell carcinoma; LIHC cis rs12701220 0.590 rs1881124 chr7:1096766 A/C cg02733842 chr7:1102375 C7orf50 -0.69 -7.68 -0.38 1.75e-13 Bronchopulmonary dysplasia; LIHC cis rs9467773 0.873 rs9295698 chr6:26566099 T/A cg09904177 chr6:26538194 HMGN4 0.66 13.84 0.6 6.58e-35 Intelligence (multi-trait analysis); LIHC cis rs6088580 0.634 rs6058041 chr20:33018008 A/G cg08999081 chr20:33150536 PIGU 0.67 13.35 0.59 5.28e-33 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg06873352 chr17:61820015 STRADA 0.74 13.35 0.59 5.24e-33 Prudent dietary pattern; LIHC cis rs1707322 0.964 rs10890358 chr1:46319025 T/A cg06784218 chr1:46089804 CCDC17 0.37 6.51 0.33 2.76e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg27286337 chr10:134555280 INPP5A 0.94 13.39 0.59 3.54e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg22199361 chr20:5081567 C20orf30 -0.44 -7.13 -0.36 6.1e-12 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11718455 0.960 rs35869565 chr3:44002394 G/C cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg18305652 chr10:134549665 INPP5A 0.44 6.28 0.32 1.05e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs950169 0.922 rs11631096 chr15:85100929 G/C cg03959625 chr15:84868606 LOC388152 0.45 6.29 0.32 9.46e-10 Schizophrenia; LIHC cis rs752010 0.714 rs6658500 chr1:42088344 A/G cg06885757 chr1:42089581 HIVEP3 -0.3 -6.21 -0.32 1.54e-9 Lupus nephritis in systemic lupus erythematosus; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg24123311 chr19:48675164 NA 0.41 6.19 0.32 1.69e-9 Bilirubin levels; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg02951883 chr7:2050386 MAD1L1 -0.78 -13.63 -0.59 4.33e-34 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs2073300 1.000 rs12625804 chr20:23441981 G/A cg12062639 chr20:23401060 NAPB 0.85 10.0 0.48 7.79e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3768617 0.510 rs2093984 chr1:183094314 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.63 0.5 5.27e-23 Fuchs's corneal dystrophy; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg05969148 chr19:51307846 C19orf48 -0.41 -6.55 -0.33 2.15e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs3213545 0.659 rs2259690 chr12:121457914 T/G cg25281562 chr12:121454272 C12orf43 0.38 6.49 0.33 2.98e-10 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg24531977 chr5:56204891 C5orf35 -0.69 -9.94 -0.47 1.28e-20 Initial pursuit acceleration; LIHC cis rs10744422 1.000 rs2343108 chr12:123331301 C/T cg25930673 chr12:123319894 HIP1R -0.93 -12.2 -0.55 1.12e-28 Schizophrenia; LIHC cis rs713477 1.000 rs10782426 chr14:55890702 G/A cg13175173 chr14:55914753 NA -0.31 -7.0 -0.35 1.33e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs9467773 1.000 rs4713008 chr6:26538268 T/C cg09904177 chr6:26538194 HMGN4 0.66 13.82 0.6 8.14e-35 Intelligence (multi-trait analysis); LIHC cis rs7945718 0.870 rs10765988 chr11:12731218 C/T cg25843174 chr11:12811716 TEAD1 0.29 6.55 0.33 2.12e-10 Educational attainment (years of education); LIHC cis rs10463316 0.608 rs7700423 chr5:150769155 C/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.7 -0.34 8.57e-11 Metabolite levels (Pyroglutamine); LIHC cis rs1552244 0.882 rs13099136 chr3:10031431 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.68 0.46 9.72e-20 Alzheimer's disease; LIHC cis rs9549367 0.789 rs71446679 chr13:113894821 C/T cg18105134 chr13:113819100 PROZ -0.66 -11.52 -0.53 3.63e-26 Platelet distribution width; LIHC cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg05368731 chr17:41323189 NBR1 0.72 12.12 0.55 2.32e-28 Menopause (age at onset); LIHC cis rs10751667 0.621 rs11246375 chr11:999620 T/C cg10932868 chr11:921992 NA 0.35 6.53 0.33 2.41e-10 Alzheimer's disease (late onset); LIHC cis rs17539620 0.624 rs4566892 chr6:154837346 C/T cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC cis rs1348850 0.914 rs6761593 chr2:178451600 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.75 -11.5 -0.53 4.42e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs17685 0.753 rs4732542 chr7:75663203 A/G cg19862616 chr7:65841803 NCRNA00174 0.86 17.86 0.69 6.99e-51 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs870825 0.860 rs72703521 chr4:185603080 T/C cg04058563 chr4:185651563 MLF1IP 0.76 6.49 0.33 3.05e-10 Blood protein levels; LIHC cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg21724239 chr8:58056113 NA 0.6 7.47 0.37 6.87e-13 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.614 rs62084387 chr17:57148027 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.35 0.56 3.04e-29 Cognitive test performance; LIHC cis rs11190604 1.000 rs10883509 chr10:102296461 C/T cg07080220 chr10:102295463 HIF1AN 0.53 7.65 0.38 2.05e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10870270 0.957 rs3829156 chr10:133789386 C/G cg08754478 chr10:133766260 PPP2R2D -0.5 -7.3 -0.37 2.06e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs907683 0.570 rs3755056 chr2:220281016 T/A cg15015639 chr2:220282977 DES 0.29 7.33 0.37 1.63e-12 Resting heart rate; LIHC cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg03264133 chr6:25882463 NA 0.56 7.57 0.38 3.61e-13 Blood metabolite levels; LIHC cis rs12824058 0.737 rs2398508 chr12:130816460 G/A cg26677194 chr12:130822605 PIWIL1 0.53 7.23 0.36 3.17e-12 Menopause (age at onset); LIHC trans rs2211698 1.000 rs2070364 chr21:35827222 G/A cg18044562 chr7:50468399 IKZF1 0.5 7.22 0.36 3.44e-12 Cancer; LIHC cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.11 15.74 0.65 2.26e-42 Gut microbiome composition (summer); LIHC cis rs17685 0.725 rs4728548 chr7:75654632 A/T cg04592579 chr7:75616294 TMEM120A -0.35 -6.08 -0.31 3.15e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1843834 0.898 rs11887386 chr2:225526975 T/G cg22455342 chr2:225449267 CUL3 0.42 5.98 0.31 5.52e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs9902453 0.817 rs2729449 chr17:28089751 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -11.88 -0.54 1.8e-27 Coffee consumption (cups per day); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg06367102 chr7:1192688 ZFAND2A 0.56 6.91 0.35 2.38e-11 Lung function (FEV1); LIHC cis rs6089584 1.000 rs6089584 chr20:60564086 G/C cg23262073 chr20:60523788 NA -0.29 -5.9 -0.3 8.92e-9 Body mass index; LIHC cis rs12142240 0.698 rs17357628 chr1:46808462 A/G cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs2625529 0.938 rs9120 chr15:72115763 G/A cg16672083 chr15:72433130 SENP8 -0.33 -6.14 -0.32 2.26e-9 Red blood cell count; LIHC cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg11062466 chr8:58055876 NA 0.52 7.07 0.36 9e-12 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.959 rs12201739 chr6:86720739 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.16 -0.48 2.32e-21 Response to antipsychotic treatment; LIHC cis rs7020830 0.858 rs1492714 chr9:37141259 T/C cg14294708 chr9:37120828 ZCCHC7 1.2 28.8 0.84 1.89e-93 Schizophrenia; LIHC cis rs12744310 1.000 rs12030372 chr1:41762029 A/G cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs769267 0.930 rs1047361 chr19:19606634 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.88 0.39 4.52e-14 Tonsillectomy; LIHC cis rs11098499 0.954 rs11940028 chr4:120411907 T/C cg09307838 chr4:120376055 NA 0.77 12.34 0.56 3.42e-29 Corneal astigmatism; LIHC cis rs9768139 0.708 rs60487292 chr7:158115342 G/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.86 -0.3 1.09e-8 Calcium levels; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg22752049 chr19:45805741 MARK4 0.5 6.06 0.31 3.64e-9 Lung function (FEV1); LIHC cis rs2032447 0.839 rs6901039 chr6:26000885 A/C cg18357526 chr6:26021779 HIST1H4A 0.87 12.43 0.56 1.59e-29 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26979339 chr12:107168153 RIC8B -0.46 -6.71 -0.34 7.96e-11 Cognitive function; LIHC cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg13409248 chr3:40428643 ENTPD3 0.4 6.6 0.34 1.52e-10 Renal cell carcinoma; LIHC cis rs8067545 0.611 rs733794 chr17:20157957 T/C cg13482628 chr17:19912719 NA -0.42 -6.88 -0.35 2.88e-11 Schizophrenia; LIHC cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg18404041 chr3:52824283 ITIH1 -0.56 -8.97 -0.44 1.94e-17 Bipolar disorder; LIHC cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.59 -0.56 4.11e-30 Alzheimer's disease; LIHC cis rs4906332 0.966 rs35799018 chr14:103893475 G/A cg19000871 chr14:103996768 TRMT61A -0.46 -7.85 -0.39 5.38e-14 Coronary artery disease; LIHC cis rs16922576 0.623 rs2104166 chr9:5230447 T/C cg02405213 chr9:5042618 JAK2 -0.64 -9.88 -0.47 1.98e-20 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7258465 1.000 rs4808801 chr19:18571141 A/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.6 -0.38 2.92e-13 Breast cancer; LIHC cis rs12477438 0.798 rs6716913 chr2:99580641 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.06 -0.51 1.7e-24 Chronic sinus infection; LIHC cis rs986417 1.000 rs1950904 chr14:60964954 G/C cg27398547 chr14:60952738 C14orf39 0.8 9.18 0.44 4.14e-18 Gut microbiota (bacterial taxa); LIHC cis rs4934494 0.636 rs34408087 chr10:91543551 G/A cg19698084 chr10:91461284 KIF20B -0.44 -5.88 -0.3 9.5e-9 Red blood cell count; LIHC cis rs2841277 0.676 rs10438246 chr14:105410183 T/C cg15352829 chr14:105391018 PLD4 -0.44 -9.39 -0.45 8.77e-19 Rheumatoid arthritis; LIHC cis rs9341808 0.727 rs9361599 chr6:81025242 C/G cg08355045 chr6:80787529 NA 0.33 6.98 0.35 1.5e-11 Sitting height ratio; LIHC trans rs2243480 1.000 rs160655 chr7:65533214 T/C cg10756647 chr7:56101905 PSPH 1.07 13.05 0.58 6.97e-32 Diabetic kidney disease; LIHC cis rs116095464 0.558 rs10056628 chr5:279512 G/A cg22496380 chr5:211416 CCDC127 -1.1 -10.33 -0.49 5.84e-22 Breast cancer; LIHC cis rs2050392 0.687 rs608693 chr10:30734971 G/A cg25182066 chr10:30743637 MAP3K8 -0.52 -8.15 -0.4 7.15e-15 Inflammatory bowel disease; LIHC cis rs61990749 0.597 rs72685264 chr14:78152998 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.59 -9.85 -0.47 2.5e-20 Fibroblast growth factor basic levels; LIHC cis rs2153535 0.563 rs1737586 chr6:8535897 C/T cg07606381 chr6:8435919 SLC35B3 0.77 11.19 0.52 5.58e-25 Motion sickness; LIHC cis rs4808199 0.947 rs2099333 chr19:19605963 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.43 6.13 0.31 2.44e-9 Nonalcoholic fatty liver disease; LIHC cis rs9467160 0.501 rs1772257 chr6:24441214 C/T cg20631270 chr6:24437470 GPLD1 -0.41 -6.09 -0.31 3.07e-9 Liver enzyme levels; LIHC cis rs3892630 0.878 rs114224536 chr19:33211232 A/G cg22980127 chr19:33182716 NUDT19 1.0 11.97 0.54 8.13e-28 Red blood cell traits; LIHC cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg06238570 chr21:40685208 BRWD1 0.48 7.75 0.39 1.07e-13 Cognitive function; LIHC cis rs10489202 0.632 rs202273 chr1:167919963 A/G cg24449463 chr1:168025552 DCAF6 -0.58 -9.57 -0.46 2.22e-19 Schizophrenia; LIHC cis rs7131987 0.874 rs10843366 chr12:29407903 T/C cg21486233 chr12:29375141 FAR2 0.3 5.82 0.3 1.36e-8 QT interval; LIHC cis rs10876993 0.821 rs1678522 chr12:58049923 G/A cg15848620 chr12:58087721 OS9 -0.55 -7.43 -0.37 8.96e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs804280 0.662 rs11250164 chr8:11610686 C/T cg26752888 chr8:11627280 NEIL2 0.56 7.37 0.37 1.28e-12 Myopia (pathological); LIHC trans rs728616 0.681 rs12769764 chr10:81917113 C/G cg03067192 chr7:72300134 SBDSP;TYW1B 0.46 6.12 0.31 2.53e-9 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs6951245 0.938 rs112425403 chr7:1071531 A/G cg08132940 chr7:1081526 C7orf50 -0.79 -6.7 -0.34 8.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs16944613 0.588 rs8024734 chr15:91107067 T/C cg26821196 chr15:91095069 CRTC3 0.45 7.58 0.38 3.22e-13 Colorectal cancer; LIHC cis rs16828019 0.852 rs34386859 chr1:41564024 C/T cg20697417 chr1:41786797 NA 0.31 5.91 0.3 8.3e-9 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.54 0.56 6.37e-30 Alzheimer's disease; LIHC cis rs7546668 1.000 rs10803392 chr1:15876758 C/T cg11706911 chr1:15910989 AGMAT 0.45 6.74 0.34 6.81e-11 Glomerular filtration rate (creatinine); LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg21747090 chr2:27597821 SNX17 -0.44 -6.71 -0.34 8.05e-11 Total body bone mineral density; LIHC cis rs2710642 0.576 rs974344 chr2:62883176 C/G cg17519650 chr2:63277830 OTX1 0.47 6.88 0.35 2.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg11494091 chr17:61959527 GH2 0.44 8.17 0.4 6.08e-15 Prudent dietary pattern; LIHC cis rs57920188 0.535 rs112660254 chr1:4089921 T/G cg20703997 chr1:4087676 NA 0.51 6.47 0.33 3.38e-10 Interleukin-17 levels; LIHC cis rs2979489 0.891 rs4449748 chr8:30304402 A/G cg26383811 chr8:30366931 RBPMS 0.73 11.97 0.54 8.28e-28 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg10862848 chr6:42927986 GNMT -0.29 -6.56 -0.33 2.03e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs8060686 0.641 rs7192187 chr16:68132109 T/C cg05110241 chr16:68378359 PRMT7 -0.57 -6.61 -0.34 1.48e-10 HDL cholesterol;Metabolic syndrome; LIHC trans rs35110281 0.807 rs6518301 chr21:45016818 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.22 0.32 1.42e-9 Mean corpuscular volume; LIHC cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg02018176 chr4:1364513 KIAA1530 0.43 5.74 0.3 2.04e-8 Longevity; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18679782 chr19:10216839 SNORD105;PPAN-P2RY11;PPAN 0.45 6.25 0.32 1.21e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10751667 0.961 rs6421967 chr11:983966 T/C cg10932868 chr11:921992 NA 0.35 6.48 0.33 3.25e-10 Alzheimer's disease (late onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06766273 chr11:62521983 ZBTB3 0.54 7.91 0.39 3.7e-14 Pancreatic cancer; LIHC cis rs709400 0.663 rs17679475 chr14:103916958 A/G cg26031613 chr14:104095156 KLC1 0.74 9.65 0.46 1.24e-19 Body mass index; LIHC cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9522267 0.535 rs56330641 chr13:112233538 C/T cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs8180040 0.726 rs34344887 chr3:47042161 A/G cg16586182 chr3:47516702 SCAP -0.48 -8.91 -0.43 3.13e-17 Colorectal cancer; LIHC cis rs9916302 0.904 rs585961 chr17:37444036 G/A cg07936489 chr17:37558343 FBXL20 0.84 13.69 0.6 2.47e-34 Glomerular filtration rate (creatinine); LIHC cis rs7044106 0.762 rs1158554 chr9:123400898 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.69 0.38 1.62e-13 Hip circumference adjusted for BMI; LIHC cis rs6545883 0.894 rs778158 chr2:61555421 A/G cg14146966 chr2:61757674 XPO1 -0.44 -7.35 -0.37 1.48e-12 Tuberculosis; LIHC cis rs80282103 0.867 rs11250242 chr10:1100064 A/C cg20335179 chr10:1068567 C10orf110;IDI2 0.55 5.77 0.3 1.78e-8 Glomerular filtration rate (creatinine); LIHC cis rs9486719 0.843 rs3860231 chr6:97036563 G/A cg06623918 chr6:96969491 KIAA0776 -0.69 -7.95 -0.4 2.69e-14 Migraine;Coronary artery disease; LIHC cis rs11077998 0.933 rs3736204 chr17:80530279 C/T cg10255544 chr17:80519551 FOXK2 0.48 8.53 0.42 4.71e-16 Reticulocyte fraction of red cells; LIHC cis rs6499255 0.951 rs60099379 chr16:69582104 A/G cg15192750 chr16:69999425 NA 0.47 6.97 0.35 1.64e-11 IgE levels; LIHC cis rs875971 0.545 rs1638735 chr7:66095738 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.99 0.31 5.44e-9 Aortic root size; LIHC cis rs2439831 0.850 rs7163245 chr15:43671294 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.76 11.16 0.52 7.29e-25 Lung cancer in ever smokers; LIHC trans rs1005277 0.579 rs1780145 chr10:38537070 A/G cg23533926 chr12:111358616 MYL2 -0.33 -6.33 -0.32 7.73e-10 Extrinsic epigenetic age acceleration; LIHC trans rs2727020 0.894 rs1880438 chr11:49370698 A/G cg03929089 chr4:120376271 NA -0.66 -9.86 -0.47 2.31e-20 Coronary artery disease; LIHC cis rs17688076 0.511 rs2418738 chr16:68122604 G/C cg09835421 chr16:68378352 PRMT7 -0.49 -6.0 -0.31 4.94e-9 C-reactive protein levels or HDL-cholesterol levels (pleiotropy); LIHC cis rs10791097 0.694 rs6590520 chr11:130747386 C/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 4.03e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12644436 0.577 rs4635785 chr4:88784220 A/G cg06891869 chr4:88767617 MEPE 0.44 7.76 0.39 9.6e-14 HIV-1 viral setpoint; LIHC cis rs950169 0.840 rs72748702 chr15:84915246 A/G cg03959625 chr15:84868606 LOC388152 0.45 6.52 0.33 2.48e-10 Schizophrenia; LIHC cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC cis rs6461049 0.800 rs2398706 chr7:2156338 A/T cg14004847 chr7:1930337 MAD1L1 -0.41 -6.06 -0.31 3.59e-9 Schizophrenia; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg07092213 chr7:1199455 ZFAND2A -0.47 -7.31 -0.37 1.9e-12 Longevity;Endometriosis; LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.06 0.55 3.63e-28 Prudent dietary pattern; LIHC cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg16049864 chr8:95962084 TP53INP1 -0.6 -11.49 -0.53 4.55e-26 Type 2 diabetes; LIHC cis rs4474465 1.000 rs2063729 chr11:78185969 C/T cg27205649 chr11:78285834 NARS2 -0.38 -5.88 -0.3 9.86e-9 Alzheimer's disease (survival time); LIHC cis rs11676855 0.927 rs4663180 chr2:235921195 A/G cg14917874 chr2:235941519 SH3BP4 0.56 7.65 0.38 2.08e-13 Dialysis-related mortality; LIHC cis rs17376456 1.000 rs34756085 chr5:93556294 A/G cg25358565 chr5:93447407 FAM172A 1.1 9.96 0.47 1.1e-20 Diabetic retinopathy; LIHC cis rs7223966 1.000 rs73337598 chr17:61732576 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 6.88 0.35 2.92e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7044106 0.762 rs1547267 chr9:123408736 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.83 0.39 6.05e-14 Hip circumference adjusted for BMI; LIHC cis rs507080 0.883 rs558593 chr11:118562520 C/T cg04173919 chr11:118528438 PHLDB1 0.35 6.58 0.34 1.73e-10 Serum metabolite levels; LIHC cis rs9649213 0.614 rs4729432 chr7:97947055 G/C cg09267113 chr7:98030324 BAIAP2L1 -0.55 -9.91 -0.47 1.62e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs7707921 0.767 rs862244 chr5:81586801 G/A cg15871215 chr5:81402204 ATG10 0.68 8.24 0.41 3.82e-15 Breast cancer; LIHC trans rs1499614 1.000 rs2707828 chr7:66171377 G/A cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg25894440 chr7:65020034 NA -0.55 -6.3 -0.32 9.1e-10 Diabetic kidney disease; LIHC cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg12310025 chr6:25882481 NA -0.6 -8.51 -0.42 5.36e-16 Blood metabolite levels; LIHC cis rs7520050 0.807 rs28647556 chr1:46206399 G/A cg03146154 chr1:46216737 IPP 0.48 8.08 0.4 1.12e-14 Red blood cell count;Reticulocyte count; LIHC trans rs17685 0.623 rs7782808 chr7:75768645 C/T cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg03351412 chr1:154909251 PMVK 0.71 10.25 0.48 1.14e-21 Prostate cancer; LIHC cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.64e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs778371 0.788 rs778355 chr2:233784749 T/G cg08000102 chr2:233561755 GIGYF2 -0.78 -8.02 -0.4 1.75e-14 Schizophrenia; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg23131131 chr22:24373011 LOC391322 0.5 6.74 0.34 6.82e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs172166 0.694 rs203884 chr6:28077374 G/T cg23485639 chr6:28045615 ZNF165 0.36 5.75 0.3 2e-8 Cardiac Troponin-T levels; LIHC cis rs72634258 0.945 rs12745223 chr1:8094978 C/T cg00042356 chr1:8021962 PARK7 0.88 8.42 0.41 1.04e-15 Inflammatory bowel disease; LIHC cis rs7772486 0.686 rs9399565 chr6:146081906 G/T cg23711669 chr6:146136114 FBXO30 -0.65 -11.6 -0.53 1.8e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs3812831 0.695 rs6560936 chr13:114945972 C/T cg06611532 chr13:114900021 NA -0.42 -7.74 -0.39 1.1e-13 Schizophrenia; LIHC cis rs10751667 0.580 rs7396041 chr11:1001607 G/A ch.11.42038R chr11:967971 AP2A2 0.59 10.87 0.51 7.54e-24 Alzheimer's disease (late onset); LIHC cis rs10791097 0.694 rs4936123 chr11:130740967 G/A cg12179176 chr11:130786555 SNX19 0.8 13.2 0.58 1.86e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6952808 0.931 rs7810038 chr7:1894116 T/C cg10360139 chr7:1886902 MAD1L1 -0.38 -5.79 -0.3 1.57e-8 Bipolar disorder and schizophrenia; LIHC cis rs7044106 0.791 rs2416798 chr9:123480603 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 10.95 0.51 3.9e-24 Hip circumference adjusted for BMI; LIHC cis rs2769264 0.602 rs11204777 chr1:151072049 G/A cg03258749 chr1:151040405 MLLT11 -0.57 -7.35 -0.37 1.45e-12 Blood trace element (Cu levels); LIHC cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg11764359 chr7:65958608 NA 0.69 9.4 0.45 8.19e-19 Aortic root size; LIHC cis rs12048904 0.964 rs8888 chr1:101338324 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 8.23 0.41 4.04e-15 Multiple sclerosis; LIHC cis rs2070488 0.931 rs6599212 chr3:38558906 T/C cg24069376 chr3:38537580 EXOG -0.39 -7.1 -0.36 7.43e-12 Electrocardiographic conduction measures; LIHC cis rs12701220 0.655 rs12702117 chr7:1148702 T/C cg04498913 chr7:1135747 C7orf50 0.44 6.97 0.35 1.68e-11 Bronchopulmonary dysplasia; LIHC cis rs7927771 1.000 rs11039390 chr11:47796295 C/G cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.39e-18 Subjective well-being; LIHC cis rs477895 0.838 rs11605738 chr11:64013406 G/A cg05555928 chr11:63887634 MACROD1 0.48 6.12 0.31 2.56e-9 Mean platelet volume; LIHC cis rs35306767 0.855 rs34251037 chr10:867884 C/T cg26597838 chr10:835615 NA 1.5 16.55 0.67 1.29e-45 Eosinophil percentage of granulocytes; LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.95 20.67 0.75 3.66e-62 Prudent dietary pattern; LIHC cis rs16866061 0.855 rs11687736 chr2:225405122 A/T cg12698349 chr2:225449008 CUL3 0.81 14.11 0.61 5.84e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs6450176 0.909 rs66872223 chr5:53292730 T/C ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.32 -0.64 1.07e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6831352 0.918 rs17218239 chr4:100057020 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC trans rs66573146 0.656 rs41410847 chr4:6957332 C/T cg07817883 chr1:32538562 TMEM39B 0.8 7.37 0.37 1.26e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs9918079 0.560 rs10008376 chr4:15623955 A/G cg16509355 chr4:15471240 CC2D2A 0.44 6.83 0.35 3.91e-11 Obesity-related traits; LIHC cis rs35146811 0.844 rs13232115 chr7:99670932 T/C cg22906224 chr7:99728672 NA 0.42 5.96 0.31 6.39e-9 Coronary artery disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00345621 chr19:1277218 C19orf24 -0.39 -6.4 -0.33 5.2400000000000005e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11212260 0.655 rs11212212 chr11:107286118 T/C cg25435332 chr11:107328525 CWF19L2 0.8 8.47 0.42 7.45e-16 IgG glycosylation; LIHC cis rs950169 0.881 rs34117475 chr15:85108443 T/C cg17507749 chr15:85114479 UBE2QP1 0.75 8.58 0.42 3.44e-16 Schizophrenia; LIHC cis rs5769765 0.730 rs62233964 chr22:50317410 C/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.74 -9.26 -0.45 2.38e-18 Schizophrenia; LIHC cis rs919433 0.519 rs700656 chr2:198653667 T/C cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.88e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.12e-15 Prudent dietary pattern; LIHC cis rs965469 1.000 rs3310 chr20:3237232 C/T cg25506879 chr20:3388711 C20orf194 -0.57 -6.78 -0.34 5.35e-11 IFN-related cytopenia; LIHC cis rs5758659 0.652 rs4822084 chr22:42435868 A/G cg04733989 chr22:42467013 NAGA -0.53 -7.48 -0.38 6.19e-13 Cognitive function; LIHC cis rs875971 0.577 rs35072105 chr7:65609817 A/G cg11764359 chr7:65958608 NA -0.67 -9.28 -0.45 1.98e-18 Aortic root size; LIHC cis rs2303759 0.918 rs1054770 chr19:49878115 G/A cg22307029 chr19:49891270 CCDC155 0.57 9.28 0.45 2.01e-18 Multiple sclerosis; LIHC cis rs1144333 0.850 rs1251273 chr1:76288617 A/G cg22875332 chr1:76189707 ACADM -0.42 -6.77 -0.34 5.58e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs7020830 0.898 rs308495 chr9:37277603 G/T cg14294708 chr9:37120828 ZCCHC7 1.04 21.76 0.76 1.69e-66 Schizophrenia; LIHC cis rs3820068 0.705 rs58424111 chr1:15868470 A/C cg17385448 chr1:15911702 AGMAT 0.4 6.81 0.35 4.41e-11 Systolic blood pressure; LIHC cis rs8114671 0.528 rs6119542 chr20:33484545 G/T cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.03e-19 Height; LIHC cis rs747782 0.646 rs75129833 chr11:47846202 T/C cg20307385 chr11:47447363 PSMC3 -0.56 -6.05 -0.31 3.89e-9 Intraocular pressure; LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg26338869 chr17:61819248 STRADA 0.59 8.69 0.43 1.5e-16 Prudent dietary pattern; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg27141850 chr2:20869434 GDF7 -0.34 -6.29 -0.32 9.66e-10 Abdominal aortic aneurysm; LIHC cis rs2180341 1.000 rs9401950 chr6:127655485 C/T cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg01300405 chr19:19626978 NDUFA13;TSSK6 -0.49 -6.07 -0.31 3.37e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1707322 1.000 rs11211236 chr1:46443767 C/A cg06784218 chr1:46089804 CCDC17 0.36 6.55 0.33 2.13e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 10.18 0.48 1.89e-21 Platelet count; LIHC cis rs1371867 0.810 rs1618528 chr8:101259134 T/C cg06636551 chr8:101224915 SPAG1 0.51 9.61 0.46 1.66e-19 Atrioventricular conduction; LIHC cis rs3796619 1.000 rs2290409 chr4:1067249 C/T cg27284194 chr4:1044797 NA -0.57 -9.81 -0.47 3.57e-20 Recombination rate (males); LIHC cis rs9309473 0.607 rs6546824 chr2:73587331 G/A cg20560298 chr2:73613845 ALMS1 -0.44 -6.99 -0.35 1.42e-11 Metabolite levels; LIHC cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg25072359 chr17:41440525 NA 0.38 6.07 0.31 3.36e-9 Menopause (age at onset); LIHC cis rs7772486 0.875 rs10457794 chr6:146415608 A/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.11 -0.31 2.75e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10197940 0.967 rs4664423 chr2:152266311 T/C cg06191203 chr2:152266755 RIF1 -0.52 -9.97 -0.47 1.04e-20 Lung cancer; LIHC cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg03060546 chr3:49711283 APEH 0.46 7.01 0.35 1.31e-11 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs892961 0.932 rs35657663 chr17:75412482 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs8078723 0.901 rs709591 chr17:38175561 T/A cg17467752 chr17:38218738 THRA 0.75 13.68 0.59 2.85e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7945705 0.870 rs10840142 chr11:8906078 A/G cg12365402 chr11:9010492 NRIP3 0.29 7.59 0.38 3.01e-13 Hemoglobin concentration; LIHC cis rs35306767 0.903 rs11253460 chr10:887382 C/G cg20503657 chr10:835505 NA 1.1 12.95 0.57 1.73e-31 Eosinophil percentage of granulocytes; LIHC cis rs4727027 0.901 rs10952792 chr7:148760501 C/T cg23583168 chr7:148888333 NA -0.68 -9.41 -0.45 7.46e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2236918 1.000 rs1635515 chr1:242017009 A/G cg17736920 chr1:242011382 EXO1 0.6 9.09 0.44 8.14e-18 Menopause (age at onset); LIHC cis rs6598955 0.670 rs6663950 chr1:26560131 T/C cg00852783 chr1:26633632 UBXN11 0.48 8.07 0.4 1.22e-14 Obesity-related traits; LIHC cis rs11997175 0.704 rs11775534 chr8:33695232 G/A cg04338863 chr8:33670619 NA 0.31 5.8 0.3 1.53e-8 Body mass index; LIHC cis rs7582720 0.943 rs72932556 chr2:203845996 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7264396 0.563 rs11698796 chr20:34248134 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.52 -6.42 -0.33 4.6e-10 Total cholesterol levels; LIHC cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg03806693 chr22:41940476 POLR3H -1.06 -12.43 -0.56 1.56e-29 Vitiligo; LIHC cis rs11098499 0.955 rs1397608 chr4:120161744 A/G cg09307838 chr4:120376055 NA 0.75 11.05 0.51 1.83e-24 Corneal astigmatism; LIHC cis rs6912958 0.559 rs446851 chr6:88043640 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.86 0.51 8.25e-24 Monocyte percentage of white cells; LIHC cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg03264133 chr6:25882463 NA -0.63 -8.85 -0.43 4.88e-17 Blood metabolite levels; LIHC cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg18225595 chr11:63971243 STIP1 0.68 8.51 0.42 5.44e-16 Mean platelet volume; LIHC cis rs1003719 0.523 rs1063949 chr21:38574675 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.51 -0.49 1.42e-22 Eye color traits; LIHC cis rs116979167 0.575 rs67661063 chr7:105187259 T/G cg19920283 chr7:105172520 RINT1 0.48 5.93 0.31 7.6e-9 Bipolar disorder (body mass index interaction); LIHC cis rs2380220 0.720 rs9374178 chr6:95979974 G/T cg04719120 chr6:96025338 MANEA 0.55 6.49 0.33 3.03e-10 Behavioural disinhibition (generation interaction); LIHC cis rs34779708 0.931 rs12771399 chr10:35452377 C/T cg04310649 chr10:35416472 CREM -0.43 -5.72 -0.3 2.3e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9303401 0.659 rs36093395 chr17:56957357 C/T cg25039879 chr17:56429692 SUPT4H1 0.79 8.95 0.44 2.32e-17 Cognitive test performance; LIHC cis rs9733 0.519 rs7511673 chr1:150707636 A/T cg18016565 chr1:150552671 MCL1 0.59 11.39 0.52 1.06e-25 Tonsillectomy; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg22903471 chr2:27725779 GCKR -0.5 -8.77 -0.43 8.6e-17 Total body bone mineral density; LIHC cis rs8062405 1.000 rs12446589 chr16:28870962 G/A cg16576597 chr16:28551801 NUPR1 0.37 5.86 0.3 1.09e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs5769707 0.967 rs9616701 chr22:50025546 G/A cg01652190 chr22:50026171 C22orf34 -0.3 -6.92 -0.35 2.2e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs5769707 0.542 rs739242 chr22:50057116 A/G cg07959070 chr22:50026188 C22orf34 -0.3 -7.22 -0.36 3.33e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7771547 0.573 rs664370 chr6:36393816 A/G cg07856975 chr6:36356162 ETV7 0.36 5.89 0.3 9.4e-9 Platelet distribution width; LIHC cis rs11098499 0.909 rs28793658 chr4:120307214 A/C cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.38e-26 Corneal astigmatism; LIHC cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg22105103 chr4:187893119 NA 0.34 8.33 0.41 1.99e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs763121 0.853 rs2294296 chr22:39053049 T/C cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs950169 0.887 rs3860265 chr15:84945185 C/T cg17507749 chr15:85114479 UBE2QP1 0.74 8.69 0.43 1.55e-16 Schizophrenia; LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg10755058 chr3:40428713 ENTPD3 0.41 7.06 0.36 9.58e-12 Renal cell carcinoma; LIHC cis rs798554 0.757 rs2644312 chr7:2841164 G/A cg04166393 chr7:2884313 GNA12 0.45 6.23 0.32 1.36e-9 Height; LIHC cis rs17384381 0.863 rs12140272 chr1:85789757 G/A cg16011679 chr1:85725395 C1orf52 0.73 7.87 0.39 4.75e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs9911578 0.681 rs8070135 chr17:56459063 G/A cg12560992 chr17:57184187 TRIM37 -0.81 -11.82 -0.54 2.93e-27 Intelligence (multi-trait analysis); LIHC cis rs1062746 0.771 rs10514621 chr16:87369578 G/T cg02258303 chr16:87377426 FBXO31 -0.42 -6.49 -0.33 3.1e-10 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); LIHC cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.01 -0.44 1.43e-17 Bipolar disorder; LIHC cis rs3008870 0.727 rs4582760 chr1:67464394 G/A cg02640540 chr1:67518911 SLC35D1 -0.41 -6.47 -0.33 3.33e-10 Lymphocyte percentage of white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19613905 chr15:56757180 MNS1 0.4 6.76 0.34 6.05e-11 Cognitive function; LIHC cis rs8062405 0.690 rs62034351 chr16:28565489 G/A cg07382826 chr16:28625726 SULT1A1 0.49 7.54 0.38 4.16e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs34779708 0.931 rs35848945 chr10:35287561 G/T cg03585969 chr10:35415529 CREM 0.85 12.86 0.57 3.79e-31 Inflammatory bowel disease;Crohn's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04252558 chr8:74884436 TCEB1 -0.51 -6.26 -0.32 1.18e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7589728 0.514 rs12465706 chr2:88467459 C/A cg14558114 chr2:88469736 THNSL2 0.59 5.76 0.3 1.91e-8 Plasma clusterin levels; LIHC cis rs17094222 0.812 rs11190644 chr10:102433046 C/T cg26540559 chr10:102447443 NA 0.33 6.41 0.33 4.83e-10 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4653767 1.000 rs708774 chr1:226921530 C/G cg05262829 chr1:226921576 ITPKB 0.43 8.44 0.42 8.83e-16 Parkinson's disease; LIHC cis rs1639906 0.895 rs78469080 chr7:2200729 G/A cg22963979 chr7:1858916 MAD1L1 0.41 5.76 0.3 1.85e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg22528358 chr1:107598549 PRMT6 -0.73 -12.36 -0.56 2.95e-29 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs67981189 0.593 rs7152845 chr14:71527223 A/G cg15816911 chr14:71606274 NA 0.42 6.81 0.35 4.46e-11 Schizophrenia; LIHC cis rs12824058 0.831 rs12320318 chr12:130812335 T/C cg24229701 chr12:130821962 PIWIL1 0.44 6.81 0.35 4.49e-11 Menopause (age at onset); LIHC cis rs10845606 1.000 rs10845607 chr12:12835228 C/T cg09462578 chr12:12878428 APOLD1 -0.77 -10.77 -0.5 1.67e-23 Systemic lupus erythematosus; LIHC cis rs8114671 0.562 rs6120746 chr20:33448496 A/G cg07148914 chr20:33460835 GGT7 0.64 9.72 0.47 6.93e-20 Height; LIHC cis rs57590327 0.503 rs12497231 chr3:81519291 A/G cg07356753 chr3:81810745 GBE1 0.46 6.84 0.35 3.7e-11 Extraversion; LIHC cis rs4853012 0.941 rs60291089 chr2:74344890 T/G cg01017244 chr2:74357527 NA 0.63 11.25 0.52 3.44e-25 Gestational age at birth (maternal effect); LIHC cis rs4908768 0.539 rs7537982 chr1:8644007 C/T cg20416874 chr1:8611966 RERE -0.63 -12.64 -0.56 2.64e-30 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4555082 0.830 rs2255575 chr14:105727251 T/C cg10792982 chr14:105748885 BRF1 0.45 6.18 0.32 1.85e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs7208859 0.573 rs7222803 chr17:29119897 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.15 0.4 7.04e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17152411 0.895 rs61872120 chr10:126583588 T/G cg07906193 chr10:126599966 NA 0.43 6.94 0.35 1.93e-11 Height; LIHC trans rs6598955 0.671 rs6681452 chr1:26621101 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.2 -0.41 4.87e-15 Obesity-related traits; LIHC cis rs1494950 1.000 rs7661252 chr4:14981989 C/T cg12377275 chr4:15005593 CPEB2 -0.82 -7.1 -0.36 7.45e-12 Political ideology; LIHC cis rs11112613 0.653 rs59504344 chr12:105950837 C/T cg03607813 chr12:105948248 NA 0.65 13.14 0.58 3.18e-32 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs9902453 0.769 rs7210288 chr17:28243473 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.61 0.53 1.76e-26 Coffee consumption (cups per day); LIHC cis rs6942756 1.000 rs12112374 chr7:128950071 A/G cg02491457 chr7:128862824 NA -0.64 -9.24 -0.45 2.77e-18 White matter hyperintensity burden; LIHC cis rs801193 0.569 rs11772819 chr7:66217970 T/C cg11764359 chr7:65958608 NA 0.74 12.55 0.56 5.73e-30 Aortic root size; LIHC cis rs4409675 0.548 rs1000432 chr1:28225119 T/C cg23691781 chr1:28212827 C1orf38 0.32 7.75 0.39 1.08e-13 Corneal astigmatism; LIHC cis rs6596100 0.538 rs66481372 chr5:132179592 T/A cg02081065 chr5:132209139 LEAP2 0.3 6.38 0.33 5.75e-10 Breast cancer; LIHC cis rs7086627 0.515 rs10887895 chr10:82210011 A/G cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs7131987 0.903 rs2194520 chr12:29423712 C/T cg16970926 chr12:29381810 FAR2 0.31 6.35 0.32 7.06e-10 QT interval; LIHC cis rs1499614 1.000 rs2659913 chr7:66157336 T/A cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs57590327 0.503 rs11711024 chr3:81910207 T/C cg07356753 chr3:81810745 GBE1 -0.5 -7.62 -0.38 2.53e-13 Extraversion; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05965430 chr12:49962171 MCRS1 0.41 6.52 0.33 2.59e-10 Calcium levels; LIHC cis rs8072100 0.676 rs7221345 chr17:45405144 G/A cg25173405 chr17:45401733 C17orf57 -0.56 -8.42 -0.41 1.05e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6540556 0.723 rs10863785 chr1:209908876 C/T cg05527609 chr1:210001259 C1orf107 0.59 8.04 0.4 1.44e-14 Red blood cell count; LIHC cis rs875971 0.862 rs35378740 chr7:65987712 C/A cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.34e-9 Aortic root size; LIHC trans rs2832191 0.633 rs2832166 chr21:30462395 G/C cg14791747 chr16:20752902 THUMPD1 -0.48 -6.6 -0.34 1.58e-10 Dental caries; LIHC cis rs796364 0.664 rs4673660 chr2:200915395 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.5 6.24 0.32 1.31e-9 Schizophrenia; LIHC cis rs4819052 0.851 rs4819043 chr21:46660078 G/A cg11663144 chr21:46675770 NA -0.33 -6.16 -0.32 2.03e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4908768 0.501 rs12046643 chr1:8547866 A/C cg20416874 chr1:8611966 RERE -0.69 -14.73 -0.62 2.25e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg03806693 chr22:41940476 POLR3H -1.09 -12.46 -0.56 1.21e-29 Vitiligo; LIHC cis rs1385374 0.920 rs61946174 chr12:129272971 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.66 0.38 1.97e-13 Systemic lupus erythematosus; LIHC cis rs67478160 0.608 rs11628787 chr14:104323984 G/A cg01849466 chr14:104193079 ZFYVE21 0.53 8.89 0.43 3.62e-17 Schizophrenia; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg05867307 chr4:144106066 USP38 0.43 6.04 0.31 3.96e-9 Morning vs. evening chronotype; LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg07308232 chr7:1071921 C7orf50 -0.47 -7.67 -0.38 1.83e-13 Longevity;Endometriosis; LIHC cis rs9733 0.527 rs11204694 chr1:150653391 G/A cg13175981 chr1:150552382 MCL1 -0.44 -6.01 -0.31 4.84e-9 Tonsillectomy; LIHC trans rs7618501 1.000 rs34451146 chr3:49813013 C/T cg21582582 chr3:182698605 DCUN1D1 0.53 6.89 0.35 2.62e-11 Intelligence (multi-trait analysis); LIHC cis rs240764 0.658 rs60658003 chr6:101201191 C/A cg12253828 chr6:101329408 ASCC3 -0.4 -6.08 -0.31 3.12e-9 Neuroticism; LIHC cis rs6754311 0.551 rs6739713 chr2:136488978 A/G cg07169764 chr2:136633963 MCM6 0.53 6.8 0.35 4.57e-11 Mosquito bite size; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02119764 chr16:53469525 RBL2 -0.41 -6.22 -0.32 1.48e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6598955 0.724 rs12726972 chr1:26639634 A/G cg04990556 chr1:26633338 UBXN11 0.58 9.21 0.45 3.39e-18 Obesity-related traits; LIHC trans rs9914544 0.545 rs4290526 chr17:18772967 T/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.52 -0.33 2.51e-10 Educational attainment (years of education); LIHC cis rs514406 0.792 rs481440 chr1:53344976 C/T cg08736216 chr1:53307985 ZYG11A -0.32 -6.13 -0.31 2.37e-9 Monocyte count; LIHC cis rs2153535 0.541 rs5026687 chr6:8473957 A/T cg07606381 chr6:8435919 SLC35B3 0.82 12.26 0.55 6.73e-29 Motion sickness; LIHC cis rs9911578 0.967 rs2611781 chr17:56703124 C/G cg12560992 chr17:57184187 TRIM37 0.97 17.45 0.69 3.2e-49 Intelligence (multi-trait analysis); LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.91 -0.3 8.35e-9 Total body bone mineral density; LIHC cis rs6500602 0.682 rs3761679 chr16:4457907 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.47 6.56 0.33 2.01e-10 Schizophrenia; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.62 -9.02 -0.44 1.39e-17 Lymphocyte counts; LIHC cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1029738 0.500 rs10264536 chr7:22884898 G/A cg11367502 chr7:22862612 TOMM7 -0.37 -6.09 -0.31 2.96e-9 Fibrinogen levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25671374 chr19:10230567 EIF3G 0.44 6.09 0.31 3.02e-9 Lung function (FEV1/FVC); LIHC trans rs801193 0.660 rs4610622 chr7:66224497 T/C cg10756647 chr7:56101905 PSPH 0.47 6.95 0.35 1.86e-11 Aortic root size; LIHC cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg16145915 chr7:1198662 ZFAND2A -0.38 -9.32 -0.45 1.52e-18 Longevity;Endometriosis; LIHC cis rs4631830 0.720 rs4935573 chr10:51504385 A/G cg16070123 chr10:51489643 NA 0.38 6.03 0.31 4.15e-9 Prostate-specific antigen levels; LIHC trans rs916888 0.773 rs199533 chr17:44828931 G/A cg16836995 chr17:43662488 NA -0.76 -7.81 -0.39 7.02e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs17270561 0.609 rs1179086 chr6:25791745 A/T cg17691542 chr6:26056736 HIST1H1C 0.44 6.01 0.31 4.75e-9 Iron status biomarkers; LIHC cis rs2070488 0.775 rs7644530 chr3:38558316 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.7 -11.45 -0.53 6.49e-26 Electrocardiographic conduction measures; LIHC cis rs9916302 0.904 rs7501488 chr17:37576417 T/G cg00129232 chr17:37814104 STARD3 -0.41 -6.38 -0.33 5.89e-10 Glomerular filtration rate (creatinine); LIHC trans rs2727020 0.729 rs10839268 chr11:49380328 G/A cg03929089 chr4:120376271 NA -0.84 -15.19 -0.63 3.57e-40 Coronary artery disease; LIHC cis rs826838 0.802 rs10785619 chr12:38742897 T/A cg26384229 chr12:38710491 ALG10B 0.56 8.88 0.43 3.89e-17 Heart rate; LIHC cis rs8058578 1.000 rs6565201 chr16:30747191 C/T cg00531865 chr16:30841666 NA -0.4 -6.07 -0.31 3.31e-9 Multiple myeloma; LIHC cis rs2073300 0.609 rs3746737 chr20:23424638 C/T cg16736954 chr20:23401023 NAPB 0.72 8.44 0.42 9.01e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17102423 0.806 rs4902362 chr14:65582755 G/A cg16583315 chr14:65563665 MAX 0.4 8.02 0.4 1.68e-14 Obesity-related traits; LIHC cis rs950169 0.922 rs17531523 chr15:85132449 C/G cg12863693 chr15:85201151 NMB 0.43 5.91 0.3 8.36e-9 Schizophrenia; LIHC cis rs8017423 0.967 rs3825662 chr14:90723152 A/G cg14092571 chr14:90743983 NA -0.38 -5.98 -0.31 5.75e-9 Mortality in heart failure; LIHC cis rs7639513 0.767 rs3806661 chr3:12705855 A/G cg23032965 chr3:12705835 RAF1 0.66 7.96 0.4 2.59e-14 Itch intensity from mosquito bite; LIHC trans rs4714291 0.832 rs761798 chr6:40087514 C/T cg02267698 chr19:7991119 CTXN1 0.39 6.59 0.34 1.67e-10 Strep throat; LIHC cis rs6060717 0.653 rs2590962 chr20:34615363 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -7.99 -0.4 2.14e-14 Hip circumference adjusted for BMI; LIHC cis rs847649 1.000 rs13233521 chr7:102593794 C/T cg18108683 chr7:102477205 FBXL13 0.47 7.31 0.37 1.96e-12 Morning vs. evening chronotype; LIHC cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.65e-9 Menopause (age at onset); LIHC cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg20887711 chr4:1340912 KIAA1530 0.47 6.04 0.31 4e-9 Obesity-related traits; LIHC cis rs9549367 0.713 rs2476328 chr13:113829350 C/T cg18105134 chr13:113819100 PROZ 0.71 12.42 0.56 1.69e-29 Platelet distribution width; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg04525508 chr3:124774877 HEG1 -0.47 -6.53 -0.33 2.36e-10 Bilirubin levels; LIHC cis rs2153535 0.562 rs6901765 chr6:8455436 A/T cg21535247 chr6:8435926 SLC35B3 0.65 8.62 0.42 2.5e-16 Motion sickness; LIHC cis rs3736485 0.932 rs4775946 chr15:51775930 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.15 -0.32 2.11e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.34 0.45 1.31e-18 Bipolar disorder; LIHC cis rs9814567 0.929 rs13316205 chr3:134223563 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.66 -12.15 -0.55 1.7e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1814175 0.817 rs10769613 chr11:49769692 G/A cg03929089 chr4:120376271 NA -0.9 -18.27 -0.7 1.6e-52 Height; LIHC cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.7 0.46 8.04e-20 Electroencephalogram traits; LIHC cis rs782590 0.608 rs10207590 chr2:55921782 G/C cg18811423 chr2:55921094 PNPT1 -0.62 -9.96 -0.47 1.12e-20 Metabolic syndrome; LIHC cis rs2991971 0.933 rs2356553 chr1:46009313 G/C cg05343316 chr1:45956843 TESK2 -0.44 -6.11 -0.31 2.69e-9 High light scatter reticulocyte count; LIHC cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.13 -0.44 6.13e-18 Bipolar disorder; LIHC cis rs4908768 0.906 rs12401496 chr1:8600401 C/T cg20416874 chr1:8611966 RERE 0.57 8.73 0.43 1.16e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs10256972 0.804 rs10275585 chr7:1017339 T/C cg16145915 chr7:1198662 ZFAND2A -0.29 -6.78 -0.34 5.17e-11 Longevity;Endometriosis; LIHC cis rs420259 0.727 rs249869 chr16:23666557 G/T cg05131483 chr16:23706242 ERN2 0.34 5.8 0.3 1.55e-8 Bipolar disorder; LIHC cis rs7923837 0.651 rs10882092 chr10:94379223 G/A cg25506282 chr10:94462361 NA 0.34 5.75 0.3 2.02e-8 Body mass index;Multiple sclerosis; LIHC cis rs7027203 0.828 rs4744291 chr9:96598297 A/G cg14598338 chr9:96623480 NA -0.33 -6.54 -0.33 2.19e-10 DNA methylation (variation); LIHC cis rs2839186 0.721 rs3788252 chr21:47661235 C/T cg13126279 chr21:47581558 C21orf56 -0.47 -7.57 -0.38 3.56e-13 Testicular germ cell tumor; LIHC trans rs9641123 0.670 rs2677089 chr7:93260091 A/T cg09745688 chr16:2908918 PRSS22 -0.37 -6.47 -0.33 3.33e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs4268898 0.760 rs4665675 chr2:24468132 C/T cg06627628 chr2:24431161 ITSN2 -0.41 -5.91 -0.3 8.08e-9 Asthma; LIHC cis rs6450176 1.000 rs7707547 chr5:53295737 A/G ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.51 -0.62 1.72e-37 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs11098499 0.954 rs13107475 chr4:120393011 A/T cg09307838 chr4:120376055 NA 0.78 12.51 0.56 8.17e-30 Corneal astigmatism; LIHC cis rs9457247 0.740 rs13195812 chr6:167443902 C/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.04 -0.4 1.46e-14 Crohn's disease; LIHC cis rs2412488 0.893 rs10007903 chr4:54341313 G/A cg22241045 chr4:54363911 LNX1 -0.41 -6.57 -0.33 1.86e-10 DNA methylation (variation); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25907053 chr2:70369816 NA -0.45 -6.3 -0.32 9.37e-10 Immature fraction of reticulocytes; LIHC cis rs4665809 0.941 rs1470096 chr2:26311482 T/C cg27170947 chr2:26402098 FAM59B -0.69 -8.53 -0.42 4.68e-16 Gut microbiome composition (summer); LIHC cis rs1728785 1.000 rs1094282 chr16:68577260 G/A cg02972257 chr16:68554789 NA -0.53 -6.1 -0.31 2.95e-9 Ulcerative colitis; LIHC cis rs427394 0.802 rs274720 chr5:6719933 A/G cg10857441 chr5:6722123 POLS -0.36 -6.27 -0.32 1.09e-9 Menopause (age at onset); LIHC cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg27211696 chr2:191398769 TMEM194B 0.66 10.85 0.51 9.37e-24 Pulse pressure; LIHC cis rs1801251 1.000 rs2675974 chr2:233727071 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.58 0.53 2.23e-26 Coronary artery disease; LIHC cis rs427394 0.659 rs419128 chr5:6739791 G/A cg10857441 chr5:6722123 POLS -0.39 -6.61 -0.34 1.47e-10 Menopause (age at onset); LIHC cis rs700651 0.753 rs10207232 chr2:198893813 A/G cg10820045 chr2:198174542 NA 0.45 6.81 0.35 4.4e-11 Intracranial aneurysm; LIHC cis rs2404602 0.735 rs12906143 chr15:76709523 T/A cg23625390 chr15:77176239 SCAPER -0.48 -7.86 -0.39 4.92e-14 Blood metabolite levels; LIHC cis rs11229555 0.609 rs34782543 chr11:58187398 G/A cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6782228 0.675 rs56141228 chr3:128386042 C/T cg16766828 chr3:128327626 NA -0.43 -6.77 -0.34 5.68e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs765787 0.530 rs7167389 chr15:45535683 A/G cg24006582 chr15:45444508 DUOX1 -0.51 -7.21 -0.36 3.52e-12 Uric acid levels; LIHC cis rs8062405 0.965 rs62037363 chr16:28865042 T/C cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs3960554 0.867 rs10239209 chr7:75804085 G/A cg19862616 chr7:65841803 NCRNA00174 0.61 8.47 0.42 7.24e-16 Eotaxin levels; LIHC cis rs9733 0.628 rs7540874 chr1:150702663 A/C cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs6674176 0.660 rs6801 chr1:44396646 C/G cg12908607 chr1:44402522 ARTN 0.49 8.27 0.41 2.92e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4808199 1.000 rs12977524 chr19:19568244 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.43 6.11 0.31 2.69e-9 Nonalcoholic fatty liver disease; LIHC cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.47 6.62 0.34 1.37e-10 Schizophrenia; LIHC cis rs9596863 0.898 rs9596847 chr13:54322250 A/G ch.13.53330881F chr13:54432880 NA 0.42 5.73 0.3 2.19e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10967178 chr1:6454278 ACOT7 0.42 6.2 0.32 1.61e-9 Pancreatic cancer; LIHC cis rs2732480 0.577 rs1489108 chr12:48738781 G/A cg21466736 chr12:48725269 NA -0.72 -10.85 -0.51 8.84e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7131987 0.903 rs7302129 chr12:29415280 A/T cg00204748 chr12:29376779 FAR2 0.42 7.7 0.38 1.44e-13 QT interval; LIHC cis rs7395581 1.000 rs7395581 chr11:47246397 G/A cg25783544 chr11:47291846 MADD -0.48 -7.01 -0.35 1.3e-11 HDL cholesterol; LIHC trans rs3960554 0.673 rs57358338 chr7:75732923 T/C cg19862616 chr7:65841803 NCRNA00174 0.62 8.75 0.43 9.65e-17 Eotaxin levels; LIHC cis rs1577917 0.958 rs10806337 chr6:86474249 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.18 -0.36 4.33e-12 Response to antipsychotic treatment; LIHC cis rs2625529 0.668 rs12914070 chr15:72334279 T/C cg16672083 chr15:72433130 SENP8 -0.31 -5.92 -0.3 8.01e-9 Red blood cell count; LIHC cis rs7572733 0.576 rs6734781 chr2:198759973 G/A cg10820045 chr2:198174542 NA 0.47 7.11 0.36 7.02e-12 Dermatomyositis; LIHC cis rs11955398 0.501 rs10067618 chr5:60010995 G/A cg02684056 chr5:59996105 DEPDC1B -0.41 -5.8 -0.3 1.47e-8 Intelligence (multi-trait analysis); LIHC cis rs7589728 1.000 rs2363731 chr2:88521793 C/T cg07952391 chr2:88470173 THNSL2 0.64 5.71 0.3 2.45e-8 Plasma clusterin levels; LIHC cis rs7613875 0.641 rs6446194 chr3:50067298 T/A cg21467203 chr3:49911342 NA 0.53 9.63 0.46 1.36e-19 Body mass index; LIHC trans rs4927850 1.000 rs7625570 chr3:195747398 A/G cg21051086 chr3:73046214 PPP4R2 -0.38 -6.23 -0.32 1.38e-9 Pancreatic cancer; LIHC cis rs11711311 1.000 rs9828449 chr3:113518602 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.84 -0.35 3.74e-11 IgG glycosylation; LIHC cis rs6912958 0.781 rs9450712 chr6:88193175 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.15 -0.36 5.25e-12 Monocyte percentage of white cells; LIHC cis rs80282103 0.867 rs12241632 chr10:1069070 A/T cg18964960 chr10:1102726 WDR37 0.62 6.17 0.32 1.95e-9 Glomerular filtration rate (creatinine); LIHC cis rs477692 1.000 rs558764 chr10:131426957 G/T cg19680672 chr10:131412579 MGMT 0.46 7.09 0.36 7.94e-12 Response to temozolomide; LIHC cis rs1538970 0.962 rs9429075 chr1:45818421 G/A cg05343316 chr1:45956843 TESK2 0.59 8.81 0.43 6.59e-17 Platelet count; LIHC cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg13126279 chr21:47581558 C21orf56 -0.39 -5.98 -0.31 5.77e-9 Testicular germ cell tumor; LIHC cis rs6448317 0.954 rs11946846 chr4:24922703 G/A cg21108841 chr4:24914750 CCDC149 -0.5 -6.32 -0.32 8.24e-10 Heschl's gyrus morphology; LIHC cis rs7100689 0.577 rs7901663 chr10:82153488 C/G cg00277334 chr10:82204260 NA -0.46 -6.65 -0.34 1.18e-10 Post bronchodilator FEV1; LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC cis rs2576037 0.583 rs11660085 chr18:44529603 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.42 5.92 0.3 7.8e-9 Personality dimensions; LIHC cis rs2760061 0.598 rs2796056 chr1:228122901 G/A cg02753203 chr1:228287806 NA -0.5 -8.05 -0.4 1.35e-14 Diastolic blood pressure; LIHC cis rs6582630 0.524 rs10785494 chr12:38532431 C/G cg26384229 chr12:38710491 ALG10B -0.48 -6.75 -0.34 6.21e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs6840360 0.571 rs62327270 chr4:152533618 C/T cg22705602 chr4:152727874 NA -0.33 -6.37 -0.33 5.98e-10 Intelligence (multi-trait analysis); LIHC cis rs34172651 0.517 rs2287783 chr16:24831727 C/T cg00339695 chr16:24857497 SLC5A11 0.74 10.86 0.51 8.51e-24 Intelligence (multi-trait analysis); LIHC cis rs11190604 1.000 rs4919472 chr10:102315864 T/A cg07080220 chr10:102295463 HIF1AN 0.52 7.08 0.36 8.02e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11586658 chr5:131563581 P4HA2 -0.58 -6.67 -0.34 1.03e-10 Systolic blood pressure; LIHC cis rs6424115 0.733 rs2502996 chr1:24199041 T/C cg15997130 chr1:24165203 NA 0.37 7.39 0.37 1.1e-12 Immature fraction of reticulocytes; LIHC cis rs9640161 0.789 rs10282458 chr7:150045302 C/T cg17279839 chr7:150038598 RARRES2 0.56 11.68 0.53 9.35e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs79149102 0.579 rs8034149 chr15:75311842 G/C cg09165964 chr15:75287851 SCAMP5 -0.61 -8.24 -0.41 3.8e-15 Lung cancer; LIHC cis rs12048904 0.533 rs1590580 chr1:101292668 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.44 6.32 0.32 8e-10 Multiple sclerosis; LIHC cis rs7520050 0.966 rs61783200 chr1:46297403 T/C cg03146154 chr1:46216737 IPP -0.4 -6.54 -0.33 2.27e-10 Red blood cell count;Reticulocyte count; LIHC cis rs28374715 0.532 rs28584379 chr15:41670408 C/G cg18705301 chr15:41695430 NDUFAF1 -1.26 -18.9 -0.71 4.78e-55 Ulcerative colitis; LIHC cis rs8177179 0.967 rs4443173 chr3:133439378 A/G cg18769074 chr3:133464867 TF 0.27 5.89 0.3 9.42e-9 Iron status biomarkers (transferrin levels); LIHC cis rs7715806 0.500 rs17563700 chr5:74986045 A/G cg19683494 chr5:74908142 NA 0.69 7.93 0.39 3.15e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11792861 0.816 rs744980 chr9:111690388 C/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.93 -0.35 2.07e-11 Menarche (age at onset); LIHC cis rs3008870 1.000 rs1925412 chr1:67405057 G/A cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC cis rs6442522 0.809 rs6805196 chr3:15451978 T/C cg16303742 chr3:15540471 COLQ 0.37 5.96 0.31 6.26e-9 Uric acid levels; LIHC cis rs7592578 0.508 rs55919641 chr2:191265414 G/A cg27211696 chr2:191398769 TMEM194B -0.46 -6.04 -0.31 4.13e-9 Diastolic blood pressure; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg11060661 chr22:24314208 DDT;DDTL 0.62 10.68 0.5 3.67e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2204008 0.702 rs3849999 chr12:38483498 G/A cg26384229 chr12:38710491 ALG10B -0.44 -6.18 -0.32 1.85e-9 Bladder cancer; LIHC cis rs3018712 0.532 rs2513280 chr11:68416907 C/G cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.12e-8 Total body bone mineral density; LIHC cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs3780486 0.801 rs3780495 chr9:33125942 A/C cg20290983 chr6:43655470 MRPS18A 1.17 30.78 0.86 1.34e-100 IgG glycosylation; LIHC cis rs1799949 0.929 rs799905 chr17:41277187 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.77 0.3 1.77e-8 Menopause (age at onset); LIHC cis rs2288073 0.965 rs10469924 chr2:24416230 G/A cg06627628 chr2:24431161 ITSN2 -0.62 -8.23 -0.41 3.89e-15 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs8017423 0.935 rs59444150 chr14:90767175 T/C cg04374321 chr14:90722782 PSMC1 0.74 14.2 0.61 2.61e-36 Mortality in heart failure; LIHC cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.54 0.46 2.76e-19 Bipolar disorder; LIHC cis rs2070488 0.730 rs2268759 chr3:38514327 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.73 11.84 0.54 2.36e-27 Electrocardiographic conduction measures; LIHC cis rs6430585 0.528 rs115469964 chr2:136696608 A/C cg25344623 chr2:136566232 LCT -0.37 -5.99 -0.31 5.2e-9 Corneal structure; LIHC cis rs950169 0.840 rs4842853 chr15:84942304 G/T cg17507749 chr15:85114479 UBE2QP1 0.74 8.65 0.42 2.04e-16 Schizophrenia; LIHC cis rs7909074 0.831 rs7903412 chr10:45382361 C/T cg04218760 chr10:45406644 TMEM72 -0.23 -7.27 -0.37 2.53e-12 Mean corpuscular volume; LIHC cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.11 10.8 0.5 1.39e-23 Platelet count; LIHC cis rs67311347 0.577 rs11712626 chr3:40259927 G/A cg00656387 chr3:40428638 ENTPD3 0.42 6.59 0.34 1.67e-10 Renal cell carcinoma; LIHC cis rs400736 0.562 rs12129505 chr1:8171734 T/C cg25007680 chr1:8021821 PARK7 -0.52 -7.49 -0.38 5.81e-13 Response to antidepressants and depression; LIHC cis rs35146811 0.586 rs10267231 chr7:99595480 T/C cg22906224 chr7:99728672 NA 0.49 6.54 0.33 2.19e-10 Coronary artery disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18513200 chr4:13629548 BOD1L -0.6 -7.16 -0.36 4.83e-12 Systolic blood pressure; LIHC cis rs2153535 0.580 rs6905242 chr6:8471799 A/C cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC trans rs1005277 0.579 rs2474574 chr10:38387295 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1790761 0.667 rs658768 chr11:67337808 G/A cg21734168 chr11:67353974 GSTP1 -0.28 -6.79 -0.34 4.99e-11 Mean corpuscular volume; LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg00656387 chr3:40428638 ENTPD3 0.47 7.78 0.39 8.83e-14 Renal cell carcinoma; LIHC cis rs2180341 1.000 rs6569486 chr6:127708424 A/C cg24812749 chr6:127587940 RNF146 1.05 15.87 0.65 7.12e-43 Breast cancer; LIHC trans rs11098499 0.954 rs11098524 chr4:120390032 A/G cg25214090 chr10:38739885 LOC399744 0.5 7.51 0.38 5.13e-13 Corneal astigmatism; LIHC cis rs67311347 0.911 rs9849224 chr3:40392562 T/C cg00656387 chr3:40428638 ENTPD3 0.41 6.87 0.35 2.97e-11 Renal cell carcinoma; LIHC cis rs9309711 0.922 rs7561600 chr2:3486093 G/C cg10845886 chr2:3471009 TTC15 -0.53 -9.77 -0.47 4.77e-20 Neurofibrillary tangles; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11418967 chr3:143689972 C3orf58 0.46 6.2 0.32 1.59e-9 Lung function (FEV1/FVC); LIHC cis rs317689 0.819 rs317677 chr12:69691806 G/A cg19645103 chr12:69753606 YEATS4 -0.47 -6.4 -0.33 5.12e-10 Response to diuretic therapy; LIHC cis rs8141529 0.702 rs132536 chr22:29302906 A/G cg15103426 chr22:29168792 CCDC117 -0.58 -9.46 -0.46 5.22e-19 Lymphocyte counts; LIHC cis rs372883 0.600 rs2832294 chr21:30739671 A/C cg08807101 chr21:30365312 RNF160 0.53 6.1 0.31 2.86e-9 Pancreatic cancer; LIHC cis rs6450176 0.556 rs111423662 chr5:53288661 T/C ch.5.1024479R chr5:53302184 ARL15 -1.02 -17.85 -0.69 8.03e-51 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg11060661 chr22:24314208 DDT;DDTL 0.62 10.82 0.5 1.18e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3018712 0.532 rs4930589 chr11:68415257 G/A cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.12e-8 Total body bone mineral density; LIHC cis rs17376456 0.877 rs10076052 chr5:93317762 C/T cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs2153535 0.580 rs7755284 chr6:8457479 T/C cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs7927592 0.913 rs11228293 chr11:68384646 T/C cg20283391 chr11:68216788 NA -0.52 -7.7 -0.38 1.43e-13 Total body bone mineral density; LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg02782426 chr3:40428986 ENTPD3 0.35 6.52 0.33 2.46e-10 Renal cell carcinoma; LIHC cis rs904251 0.772 rs1812186 chr6:37465916 T/C cg01843034 chr6:37503916 NA -0.42 -6.75 -0.34 6.51e-11 Cognitive performance; LIHC cis rs4927850 0.752 rs7624460 chr3:195748530 C/T cg12923728 chr3:195709715 SDHAP1 -0.7 -10.33 -0.49 5.77e-22 Pancreatic cancer; LIHC cis rs7412746 0.611 rs2271076 chr1:150916657 C/T cg17724175 chr1:150552817 MCL1 0.38 7.59 0.38 3.03e-13 Melanoma; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg03721293 chr16:90014378 DEF8 0.39 6.53 0.33 2.32e-10 Skin colour saturation; LIHC cis rs6121246 0.779 rs6060763 chr20:30282223 A/G cg13852791 chr20:30311386 BCL2L1 0.85 8.77 0.43 8.65e-17 Mean corpuscular hemoglobin; LIHC cis rs7959452 0.558 rs1478464 chr12:69779789 G/C cg19645103 chr12:69753606 YEATS4 -0.39 -5.8 -0.3 1.54e-8 Blood protein levels; LIHC cis rs899997 1.000 rs11629824 chr15:79005524 T/G cg04896959 chr15:78267971 NA 0.4 7.82 0.39 6.73e-14 Coronary artery disease or large artery stroke; LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg10755058 chr3:40428713 ENTPD3 -0.42 -7.26 -0.37 2.61e-12 Renal cell carcinoma; LIHC cis rs8078723 1.000 rs4795416 chr17:38158133 C/T cg17467752 chr17:38218738 THRA 0.76 13.74 0.6 1.6e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg02034447 chr16:89574710 SPG7 0.49 7.38 0.37 1.25e-12 Multiple myeloma (IgH translocation); LIHC cis rs7911264 0.628 rs7921040 chr10:94418425 G/A cg00519463 chr10:94352821 KIF11 -0.47 -6.43 -0.33 4.27e-10 Inflammatory bowel disease; LIHC cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg13395646 chr4:1353034 KIAA1530 -0.66 -9.5 -0.46 3.75e-19 Obesity-related traits; LIHC cis rs1639906 0.895 rs35038526 chr7:2213106 A/G cg02951883 chr7:2050386 MAD1L1 0.56 7.47 0.37 6.56e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs7223966 0.883 rs2727317 chr17:61961302 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.52 0.33 2.51e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7131987 0.934 rs7316004 chr12:29411698 C/T cg16970926 chr12:29381810 FAR2 0.32 6.8 0.34 4.75e-11 QT interval; LIHC cis rs10927875 0.832 rs4661342 chr1:16160773 C/G cg21385522 chr1:16154831 NA -1.08 -13.54 -0.59 9.58e-34 Dilated cardiomyopathy; LIHC cis rs1552244 0.882 rs3755783 chr3:10029289 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.21 -0.45 3.39e-18 Alzheimer's disease; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg22996534 chr8:17658847 MTUS1 -0.59 -6.09 -0.31 3.04e-9 Obesity-related traits; LIHC cis rs1256061 0.603 rs1256039 chr14:64738979 G/C cg23250157 chr14:64679961 SYNE2 0.41 6.07 0.31 3.45e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs2836950 0.509 rs4816618 chr21:40599529 G/A cg06238570 chr21:40685208 BRWD1 -0.43 -6.81 -0.35 4.53e-11 Menarche (age at onset); LIHC cis rs6121246 0.567 rs6060297 chr20:30198560 A/G cg13852791 chr20:30311386 BCL2L1 0.76 6.81 0.35 4.53e-11 Mean corpuscular hemoglobin; LIHC cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg01017244 chr2:74357527 NA 0.63 11.31 0.52 2e-25 Gestational age at birth (maternal effect); LIHC cis rs1062177 1.000 rs973529 chr5:151188158 T/C cg00977110 chr5:151150581 G3BP1 0.54 6.9 0.35 2.47e-11 Preschool internalizing problems; LIHC cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.49 -0.46 4.06e-19 Bipolar disorder; LIHC cis rs17253792 0.822 rs17685102 chr14:56129214 A/G cg01858014 chr14:56050164 KTN1 -0.71 -7.22 -0.36 3.38e-12 Putamen volume; LIHC trans rs79976124 0.800 rs12194767 chr6:66639599 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.68 7.43 0.37 8.72e-13 Type 2 diabetes; LIHC cis rs929354 0.772 rs6971896 chr7:156978412 C/T cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs4555082 0.834 rs2735825 chr14:105710900 G/A cg10792982 chr14:105748885 BRF1 0.49 6.34 0.32 7.17e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs6456156 0.586 rs12198816 chr6:167483546 G/A cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.06e-9 Primary biliary cholangitis; LIHC cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg13395646 chr4:1353034 KIAA1530 -0.63 -9.0 -0.44 1.55e-17 Obesity-related traits; LIHC cis rs965469 1.000 rs6037532 chr20:3267911 T/C cg25506879 chr20:3388711 C20orf194 -0.58 -7.06 -0.36 9.15e-12 IFN-related cytopenia; LIHC cis rs7208859 0.673 rs3764420 chr17:29164154 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs332507 0.869 rs3772784 chr3:124394657 A/G cg05980111 chr3:124395277 KALRN 0.36 6.13 0.31 2.47e-9 Plateletcrit; LIHC trans rs526821 0.595 rs624478 chr11:55340778 C/G cg03929089 chr4:120376271 NA -0.45 -6.84 -0.35 3.59e-11 Pediatric bone mineral density (spine); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19332409 chr7:156467866 RNF32 -0.45 -6.67 -0.34 1.02e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4727027 0.704 rs7784122 chr7:148904624 A/G cg23583168 chr7:148888333 NA 0.79 11.76 0.54 4.87e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs10927875 0.501 rs61782229 chr1:16220118 G/A cg21385522 chr1:16154831 NA -1.05 -11.69 -0.53 8.49e-27 Dilated cardiomyopathy; LIHC cis rs5753618 0.561 rs714909 chr22:31741067 G/A cg07713946 chr22:31675144 LIMK2 0.41 7.29 0.37 2.2e-12 Colorectal cancer; LIHC cis rs2439831 0.681 rs825740 chr15:43592408 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.86 15.79 0.65 1.42e-42 Lung cancer in ever smokers; LIHC cis rs11122272 0.668 rs2790874 chr1:231537988 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.47 -0.49 1.97e-22 Hemoglobin concentration; LIHC cis rs3749237 0.576 rs4241406 chr3:49600426 C/T cg02487422 chr3:49467188 NICN1 0.38 5.78 0.3 1.65e-8 Resting heart rate; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg16574807 chr4:6945745 TBC1D14 0.39 6.3 0.32 9.17e-10 Bilirubin levels; LIHC trans rs1005277 0.579 rs1740732 chr10:38491385 C/T cg23533926 chr12:111358616 MYL2 -0.34 -6.64 -0.34 1.21e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9649465 0.561 rs2429618 chr7:123421662 G/A cg03229431 chr7:123269106 ASB15 0.43 9.17 0.44 4.56e-18 Migraine; LIHC cis rs10861342 0.892 rs2044307 chr12:105531171 G/T cg23923672 chr12:105501055 KIAA1033 0.65 7.59 0.38 3.01e-13 IgG glycosylation; LIHC cis rs9814567 1.000 rs6802654 chr3:134217072 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.96 -0.31 6.34e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs56775891 0.959 rs11663602 chr18:77578191 G/T cg13263691 chr18:77568018 NA 0.23 6.17 0.32 1.93e-9 Schizophrenia; LIHC cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg08888203 chr3:10149979 C3orf24 0.62 6.93 0.35 2.15e-11 Alzheimer's disease; LIHC cis rs929354 0.742 rs3808316 chr7:156944787 C/G cg16102536 chr7:156981717 UBE3C 0.36 6.03 0.31 4.18e-9 Body mass index; LIHC cis rs9486719 1.000 rs72931061 chr6:96880285 G/A cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg22663859 chr13:21900854 NA 0.48 7.9 0.39 3.76e-14 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7618501 0.633 rs7621026 chr3:49975334 A/G cg24110177 chr3:50126178 RBM5 -0.47 -7.67 -0.38 1.86e-13 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs13077641 chr3:10022935 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs67478160 0.643 rs12880821 chr14:104276049 C/T cg08213375 chr14:104286397 PPP1R13B 0.64 12.12 0.55 2.24e-28 Schizophrenia; LIHC cis rs6089584 0.854 rs6061407 chr20:60622048 A/C cg13770153 chr20:60521292 NA -0.33 -6.62 -0.34 1.4e-10 Body mass index; LIHC trans rs2797160 0.837 rs1739364 chr6:126022383 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.47 -6.62 -0.34 1.42e-10 Endometrial cancer; LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg04267008 chr7:1944627 MAD1L1 0.62 10.03 0.48 6.5e-21 Bipolar disorder and schizophrenia; LIHC cis rs66887589 0.870 rs59590064 chr4:120539753 T/C cg09307838 chr4:120376055 NA -0.46 -6.86 -0.35 3.32e-11 Diastolic blood pressure; LIHC cis rs11252926 0.527 rs10904093 chr10:436848 A/G cg16346588 chr10:242978 ZMYND11 -0.39 -6.01 -0.31 4.88e-9 Psychosis in Alzheimer's disease; LIHC cis rs7647973 0.710 rs11130208 chr3:49615624 G/T cg03060546 chr3:49711283 APEH 0.62 6.96 0.35 1.76e-11 Menarche (age at onset); LIHC cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg12463550 chr7:65579703 CRCP -0.66 -6.83 -0.35 3.91e-11 Diabetic kidney disease; LIHC cis rs4665809 0.887 rs4665825 chr2:26333100 A/G cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs6596100 0.538 rs34626261 chr5:132174880 A/C cg02081065 chr5:132209139 LEAP2 0.29 6.16 0.32 2.05e-9 Breast cancer; LIHC cis rs7264396 1.000 rs224440 chr20:34159447 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.38 -6.67 -0.34 1.04e-10 Total cholesterol levels; LIHC trans rs1422110 0.543 rs768240 chr5:85420954 C/T cg01787110 chr1:109008453 NBPF6 -0.28 -6.31 -0.32 8.87e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs6582630 0.519 rs12582285 chr12:38298753 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.21 0.41 4.57e-15 Drug-induced liver injury (flucloxacillin); LIHC trans rs8002861 0.870 rs1348671 chr13:44449505 C/T cg17145862 chr1:211918768 LPGAT1 0.57 10.55 0.5 1.05e-22 Leprosy; LIHC cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.41 0.45 7.44e-19 Bipolar disorder; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg20985075 chr1:35325271 C1orf212 -0.4 -6.05 -0.31 3.73e-9 Eotaxin levels; LIHC cis rs9918079 0.542 rs6414765 chr4:15626493 G/A cg21123203 chr4:15471301 CC2D2A -0.44 -6.97 -0.35 1.69e-11 Obesity-related traits; LIHC cis rs854765 0.647 rs2974999 chr17:17997547 T/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.34 6.25 0.32 1.24e-9 Total body bone mineral density; LIHC cis rs8077889 0.871 rs7212648 chr17:41917962 A/C cg26893861 chr17:41843967 DUSP3 0.99 10.98 0.51 3.27e-24 Triglycerides; LIHC cis rs11958404 0.860 rs72818116 chr5:157440616 G/T cg05962755 chr5:157440814 NA 0.99 11.5 0.53 4.32e-26 IgG glycosylation; LIHC cis rs2204008 0.776 rs8186824 chr12:38316537 A/C cg26384229 chr12:38710491 ALG10B 0.58 8.12 0.4 8.47e-15 Bladder cancer; LIHC cis rs2749592 0.588 rs2504144 chr10:38383525 C/T cg00409905 chr10:38381863 ZNF37A -0.53 -8.44 -0.42 9.05e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7412746 0.611 rs12410869 chr1:150856153 G/T cg17724175 chr1:150552817 MCL1 0.39 7.79 0.39 8.31e-14 Melanoma; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg19469297 chr7:45151440 TBRG4 -0.45 -6.79 -0.34 5.07e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7223966 1.000 rs6504168 chr17:61697469 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.54 0.33 2.26e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs11122272 0.735 rs2250719 chr1:231486208 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.06 -0.51 1.58e-24 Hemoglobin concentration; LIHC cis rs4975616 0.804 rs31489 chr5:1342714 C/A cg06550200 chr5:1325588 CLPTM1L -0.64 -10.11 -0.48 3.43e-21 Lung cancer; LIHC cis rs6088580 0.634 rs1205338 chr20:32925625 C/G cg08999081 chr20:33150536 PIGU -0.67 -13.27 -0.58 1.02e-32 Glomerular filtration rate (creatinine); LIHC cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.15e-51 Menopause (age at onset); LIHC cis rs939574 1.000 rs7574937 chr2:220099331 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.99 10.78 0.5 1.65e-23 Platelet distribution width; LIHC cis rs875971 1.000 rs778685 chr7:65836176 G/T cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg02782426 chr3:40428986 ENTPD3 0.33 6.14 0.32 2.24e-9 Renal cell carcinoma; LIHC cis rs7772486 0.713 rs79248977 chr6:146319388 C/A cg23711669 chr6:146136114 FBXO30 0.63 10.31 0.49 7.02e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs61776719 0.875 rs10890238 chr1:38445654 A/T cg12658694 chr1:38397304 INPP5B 0.63 9.92 0.47 1.52e-20 Coronary artery disease; LIHC cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs6785206 0.614 rs2712430 chr3:128337438 A/C cg16766828 chr3:128327626 NA -0.62 -6.91 -0.35 2.38e-11 Lymphocyte percentage of white cells; LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.18 0.55 1.36e-28 Prudent dietary pattern; LIHC cis rs6754311 0.773 rs4988183 chr2:136622046 T/C cg07305463 chr2:136567211 LCT -0.34 -6.42 -0.33 4.52e-10 Mosquito bite size; LIHC cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg23649088 chr2:200775458 C2orf69 0.58 8.42 0.41 1.07e-15 Osteoporosis; LIHC cis rs712039 0.652 rs853196 chr17:35848659 A/T cg16670864 chr17:35848621 DUSP14 0.34 5.75 0.3 1.97e-8 Tuberculosis; LIHC cis rs77633900 0.772 rs387321 chr15:76743565 A/G cg21673338 chr15:77095150 SCAPER -0.51 -5.95 -0.31 6.51e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs7208859 0.623 rs7208441 chr17:29143863 C/T cg14067834 chr17:29058358 SUZ12P 0.71 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg18306943 chr3:40428807 ENTPD3 0.35 6.09 0.31 3.1e-9 Renal cell carcinoma; LIHC cis rs4930103 0.935 rs4930098 chr11:2020955 G/C cg06197492 chr11:2016605 H19 0.37 5.91 0.3 8.11e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09799432 chr1:87170127 SH3GLB1 -0.45 -6.12 -0.31 2.58e-9 Pancreatic cancer; LIHC cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg09913183 chr17:42254507 C17orf65;ASB16 0.69 10.05 0.48 5.25e-21 Total body bone mineral density; LIHC cis rs2073300 1.000 rs6132625 chr20:23444671 C/T cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7909074 0.531 rs879344 chr10:45400667 G/C cg05187965 chr10:45406764 TMEM72 -0.24 -5.72 -0.3 2.38e-8 Mean corpuscular volume; LIHC cis rs9399135 0.622 rs3817776 chr6:135256756 C/T cg22676075 chr6:135203613 NA -0.39 -6.32 -0.32 8.02e-10 Red blood cell count; LIHC cis rs6424115 1.000 rs35385477 chr1:24155924 G/A cg10978503 chr1:24200527 CNR2 0.37 8.7 0.43 1.38e-16 Immature fraction of reticulocytes; LIHC trans rs3813567 0.759 rs12148319 chr15:78956192 A/G cg24133106 chr7:129690864 ZC3HC1 -0.49 -6.13 -0.31 2.38e-9 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; LIHC trans rs1814175 0.645 rs1963215 chr11:49931486 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs6960043 1.000 rs6962498 chr7:15050305 C/G cg19272540 chr7:15055459 NA -0.23 -6.24 -0.32 1.32e-9 Type 2 diabetes; LIHC cis rs926392 0.589 rs6093115 chr20:37693817 T/C cg16355469 chr20:37678765 NA 0.48 6.97 0.35 1.63e-11 Dialysis-related mortality; LIHC cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg06873352 chr17:61820015 STRADA -0.54 -8.76 -0.43 9.2e-17 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg08888203 chr3:10149979 C3orf24 0.57 6.76 0.34 5.85e-11 Alzheimer's disease; LIHC cis rs6450176 0.564 rs374050 chr5:53331646 C/G ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.5 -0.59 1.4e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs5769707 0.681 rs2319346 chr22:50029640 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.29 -0.41 2.58e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.48 0.46 4.45e-19 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11212172 chr10:53459438 PRKG1;CSTF2T 0.49 6.91 0.35 2.37e-11 Pancreatic cancer; LIHC cis rs2574704 0.810 rs11708985 chr3:11651896 G/C cg15876825 chr3:11651881 VGLL4 -0.52 -8.5 -0.42 6.14e-16 Body mass index; LIHC cis rs7845219 0.544 rs7001535 chr8:95921090 C/G cg16049864 chr8:95962084 TP53INP1 -0.44 -6.43 -0.33 4.24e-10 Type 2 diabetes; LIHC cis rs7551222 0.749 rs11240764 chr1:204569376 A/G cg20240347 chr1:204465584 NA -0.31 -6.36 -0.33 6.39e-10 Schizophrenia; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg06420487 chr17:61919686 SMARCD2 0.44 6.01 0.31 4.68e-9 Height; LIHC cis rs2204008 0.715 rs3899385 chr12:38169880 C/G cg13010199 chr12:38710504 ALG10B 0.48 5.71 0.3 2.42e-8 Bladder cancer; LIHC cis rs875971 1.000 rs4717300 chr7:65947380 T/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs1215050 0.791 rs700738 chr4:98907909 C/A cg05340658 chr4:99064831 C4orf37 -0.4 -6.03 -0.31 4.16e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs8078723 0.714 rs8070444 chr17:38151960 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.66 11.37 0.52 1.29e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs6897795 0.680 rs9329137 chr5:177616370 C/T cg19598605 chr2:70056955 GMCL1 -0.53 -7.16 -0.36 4.9e-12 Plateletcrit; LIHC cis rs17685 0.753 rs1574107 chr7:75685047 A/C cg16684958 chr7:75615977 POR 0.51 8.48 0.42 7.08e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg12463550 chr7:65579703 CRCP 0.69 7.34 0.37 1.6e-12 Diabetic kidney disease; LIHC cis rs4631830 0.863 rs4935162 chr10:51525699 C/G cg20129853 chr10:51489980 NA -0.41 -9.02 -0.44 1.34e-17 Prostate-specific antigen levels; LIHC cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.59 0.56 3.89e-30 Colorectal cancer; LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg08280861 chr8:58055591 NA 0.49 6.05 0.31 3.9e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 0.901 rs778693 chr7:65872345 T/G cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC cis rs9457247 0.935 rs1044059 chr6:167369897 C/A cg12798992 chr6:167411361 FGFR1OP -0.6 -9.68 -0.46 9.68e-20 Crohn's disease; LIHC cis rs7703051 0.513 rs59014134 chr5:74589385 C/T cg07671805 chr5:74907694 NA 0.45 5.84 0.3 1.24e-8 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs11945232 1.000 rs28609242 chr4:88342497 T/C cg23841344 chr4:88312519 HSD17B11 -0.59 -7.88 -0.39 4.35e-14 Intelligence (multi-trait analysis); LIHC cis rs11718455 1.000 rs4682928 chr3:44037192 T/C cg08738300 chr3:44038990 NA 0.52 9.04 0.44 1.2e-17 Coronary artery disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24162759 chr1:224622126 WDR26 0.43 6.16 0.32 2.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1153858 0.945 rs1974981 chr15:45729123 C/T cg21132104 chr15:45694354 SPATA5L1 -0.38 -6.07 -0.31 3.35e-9 Homoarginine levels; LIHC cis rs34779708 0.931 rs7079498 chr10:35375344 C/T cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.52e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs763121 0.853 rs2064088 chr22:39053382 A/G cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs7772486 0.875 rs10457792 chr6:146412415 T/C cg23711669 chr6:146136114 FBXO30 0.57 9.77 0.47 4.67e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs4660306 1.000 rs6429567 chr1:45956700 C/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.64 -7.61 -0.38 2.7e-13 Homocysteine levels; LIHC cis rs2228479 0.850 rs2238531 chr16:89856217 C/G cg06558623 chr16:89946397 TCF25 0.85 11.06 0.51 1.62e-24 Skin colour saturation; LIHC cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.9e-9 Menopause (age at onset); LIHC cis rs2576037 0.526 rs538221 chr18:44375111 G/A cg19077165 chr18:44547161 KATNAL2 -0.41 -6.33 -0.32 7.6e-10 Personality dimensions; LIHC cis rs6752107 0.936 rs10192702 chr2:234206750 A/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.51 7.6 0.38 2.88e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg02290350 chr8:58132656 NA 0.48 9.01 0.44 1.51e-17 Developmental language disorder (linguistic errors); LIHC cis rs2115630 1.000 rs11854291 chr15:85363708 T/C cg12501888 chr15:85177176 SCAND2 -0.48 -7.33 -0.37 1.69e-12 P wave terminal force; LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg00106254 chr7:1943704 MAD1L1 0.41 6.64 0.34 1.24e-10 Bipolar disorder and schizophrenia; LIHC cis rs10751667 0.621 rs4075990 chr11:976614 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs1003719 0.788 rs2835582 chr21:38458773 C/G cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.22 0.55 9.97e-29 Eye color traits; LIHC cis rs10751667 1.000 rs7927156 chr11:970607 A/G cg06064525 chr11:970664 AP2A2 -0.45 -10.7 -0.5 3.06e-23 Alzheimer's disease (late onset); LIHC cis rs11792861 0.505 rs12377869 chr9:111907803 C/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.58 9.11 0.44 7.34e-18 Menarche (age at onset); LIHC cis rs780096 0.546 rs715325 chr2:27725572 C/A cg22903471 chr2:27725779 GCKR -0.54 -9.56 -0.46 2.33e-19 Total body bone mineral density; LIHC cis rs9443645 0.901 rs1542977 chr6:79550307 G/T cg05283184 chr6:79620031 NA -0.33 -5.72 -0.3 2.27e-8 Intelligence (multi-trait analysis); LIHC cis rs7212590 0.618 rs7219051 chr17:58032710 G/A cg10252138 chr17:58120427 NA -0.58 -5.87 -0.3 1.01e-8 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg23758822 chr17:41437982 NA 0.93 17.45 0.69 3.28e-49 Menopause (age at onset); LIHC cis rs6088590 0.707 rs67159833 chr20:33488079 T/C cg06115741 chr20:33292138 TP53INP2 0.63 8.39 0.41 1.34e-15 Coronary artery disease; LIHC cis rs7520050 0.931 rs785472 chr1:46518288 T/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.84 0.3 1.24e-8 Red blood cell count;Reticulocyte count; LIHC trans rs3780486 0.522 rs7029897 chr9:33124042 T/C cg20290983 chr6:43655470 MRPS18A 0.96 20.52 0.74 1.45e-61 IgG glycosylation; LIHC cis rs754466 0.606 rs11002315 chr10:79617385 T/G cg17075019 chr10:79541650 NA -0.76 -11.66 -0.53 1.11e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6456156 0.586 rs12528323 chr6:167461645 A/G cg12798992 chr6:167411361 FGFR1OP 0.43 6.73 0.34 7.25e-11 Primary biliary cholangitis; LIHC cis rs797680 0.821 rs2391254 chr1:93795166 A/T cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.9 -0.3 8.86e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs34779708 0.966 rs4934734 chr10:35434373 T/C cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.67 0.42 1.73e-16 Platelet count; LIHC cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg09177884 chr7:1199841 ZFAND2A -0.43 -6.0 -0.31 5.09e-9 Longevity;Endometriosis; LIHC cis rs10463316 0.747 rs10077700 chr5:150768324 A/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.68 -0.34 9.73e-11 Metabolite levels (Pyroglutamine); LIHC cis rs6598955 0.724 rs7526545 chr1:26569990 C/A cg04990556 chr1:26633338 UBXN11 -0.61 -10.12 -0.48 3.16e-21 Obesity-related traits; LIHC cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.7 0.69 3.05e-50 Gut microbiome composition (summer); LIHC cis rs7945718 0.967 rs11826129 chr11:12768883 G/A cg25843174 chr11:12811716 TEAD1 0.35 8.04 0.4 1.52e-14 Educational attainment (years of education); LIHC cis rs9457247 0.508 rs9457268 chr6:167503639 A/T cg07741184 chr6:167504864 NA 0.29 7.29 0.37 2.12e-12 Crohn's disease; LIHC cis rs9291683 0.595 rs13145442 chr4:10037261 C/A cg11266682 chr4:10021025 SLC2A9 0.35 7.44 0.37 8.24e-13 Bone mineral density; LIHC cis rs3960554 1.000 rs78663390 chr7:75845837 C/A cg01364799 chr7:75623366 TMEM120A -0.47 -6.47 -0.33 3.45e-10 Eotaxin levels; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg17100207 chr8:21776848 XPO7 -0.5 -6.14 -0.32 2.26e-9 Monocyte count; LIHC cis rs9611565 0.649 rs9623450 chr22:42175231 G/A cg03806693 chr22:41940476 POLR3H 0.79 8.66 0.42 1.89e-16 Vitiligo; LIHC cis rs6933660 0.760 rs1825368 chr6:151775259 C/A cg14262678 chr6:151773367 RMND1;C6orf211 0.51 7.43 0.37 8.8e-13 Menarche (age at onset); LIHC cis rs2153535 0.580 rs1577468 chr6:8444266 C/A cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs9911578 0.935 rs302873 chr17:56769481 C/G cg12560992 chr17:57184187 TRIM37 0.98 17.57 0.69 1.09e-49 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.789 rs9355748 chr6:160194882 G/A cg11366901 chr6:160182831 ACAT2 0.92 15.34 0.64 8.99e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs17106184 0.892 rs72902708 chr1:51213677 C/T cg07174182 chr1:51127561 FAF1 -0.64 -7.3 -0.37 2.04e-12 Type 2 diabetes; LIHC trans rs4566357 0.615 rs4675140 chr2:227908665 C/T cg16088116 chr21:44841560 SIK1 -0.4 -6.11 -0.31 2.7e-9 Coronary artery disease; LIHC cis rs785830 0.717 rs600951 chr9:224742 A/G cg14500300 chr9:211689 NA 0.27 6.18 0.32 1.81e-9 Platelet distribution width; LIHC cis rs714515 0.511 rs9425301 chr1:172363815 A/C cg01573306 chr1:172330400 DNM3 0.38 5.73 0.3 2.16e-8 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs9467773 1.000 rs11756120 chr6:26529808 G/C cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg13409248 chr3:40428643 ENTPD3 0.43 6.92 0.35 2.2e-11 Renal cell carcinoma; LIHC cis rs9611565 1.000 rs5758314 chr22:41762523 T/G cg03806693 chr22:41940476 POLR3H -0.47 -6.22 -0.32 1.47e-9 Vitiligo; LIHC cis rs2455799 0.573 rs2455812 chr3:15734096 C/G cg12698662 chr3:15914712 MIR563 -0.37 -6.8 -0.35 4.64e-11 Mean platelet volume; LIHC cis rs864643 0.945 rs614453 chr3:39582567 C/T cg05136238 chr3:39556330 MOBP 0.34 5.78 0.3 1.66e-8 Attention deficit hyperactivity disorder; LIHC cis rs11105298 0.891 rs3741899 chr12:89933931 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.53 -0.38 4.6e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15731816 chr14:75230414 YLPM1 0.39 7.04 0.36 1.04e-11 Cognitive function; LIHC cis rs651907 0.535 rs58658478 chr3:101511667 G/A cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.9 -0.3 8.91e-9 Colorectal cancer; LIHC cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg18252515 chr7:66147081 NA -1.24 -15.85 -0.65 7.92e-43 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06826115 chr15:67835137 MAP2K5 -0.46 -6.12 -0.31 2.5e-9 Pancreatic cancer; LIHC cis rs12477438 0.798 rs896886 chr2:99652713 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.81 12.21 0.55 1.07e-28 Chronic sinus infection; LIHC cis rs1552244 0.554 rs7638846 chr3:10048601 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.61 8.39 0.41 1.26e-15 Alzheimer's disease; LIHC cis rs7659604 0.502 rs4315813 chr4:122674866 G/A cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.7e-11 Type 2 diabetes; LIHC cis rs11626933 1.000 rs2236402 chr14:90734378 C/G cg14092571 chr14:90743983 NA -0.89 -14.66 -0.62 4.07e-38 Gut microbiota (bacterial taxa); LIHC cis rs797680 0.891 rs9432453 chr1:93771629 G/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.97 -0.31 5.84e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs17286411 0.750 rs4788568 chr16:71913025 C/T cg06353428 chr16:71660113 MARVELD3 0.56 7.06 0.36 9.2e-12 Blood protein levels; LIHC cis rs730775 0.505 rs325004 chr6:44270365 C/G cg21130236 chr6:44246755 TMEM151B -0.23 -6.62 -0.34 1.37e-10 Monocyte percentage of white cells;Monocyte count; LIHC cis rs703842 0.616 rs871871 chr12:58219681 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.69 9.52 0.46 3.34e-19 Multiple sclerosis; LIHC cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg16049864 chr8:95962084 TP53INP1 -0.63 -11.71 -0.54 7.14e-27 Type 2 diabetes; LIHC trans rs1945213 0.694 rs12222077 chr11:55848116 T/A cg03929089 chr4:120376271 NA 0.53 6.8 0.35 4.54e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs7572733 0.534 rs1401091 chr2:198790423 T/G cg03934865 chr2:198174659 NA -0.47 -6.84 -0.35 3.6e-11 Dermatomyositis; LIHC cis rs3845702 0.736 rs6433816 chr2:180809317 G/C cg01881094 chr2:180872142 CWC22 -1.17 -10.09 -0.48 3.91e-21 Schizophrenia; LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs7267979 1.000 rs2259956 chr20:25282433 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg07677032 chr17:61819896 STRADA 0.43 6.2 0.32 1.62e-9 Prudent dietary pattern; LIHC cis rs2050392 0.517 rs656600 chr10:30765654 G/A cg02070205 chr10:30722105 MAP3K8 -0.43 -5.75 -0.3 1.97e-8 Inflammatory bowel disease; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.27 0.55 6.03e-29 Prudent dietary pattern; LIHC cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg20090690 chr10:134436459 INPP5A 0.45 6.27 0.32 1.1e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12079745 0.623 rs12091133 chr1:169387826 T/A cg09363564 chr1:169337483 NME7;BLZF1 -0.82 -7.17 -0.36 4.62e-12 QT interval; LIHC cis rs2304069 0.954 rs1433010 chr5:149383954 C/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.99 -13.1 -0.58 4.68e-32 HIV-1 control; LIHC cis rs4595586 0.545 rs1375796 chr12:39410592 G/T cg26384229 chr12:38710491 ALG10B 0.53 6.48 0.33 3.12e-10 Morning vs. evening chronotype; LIHC cis rs35306767 0.716 rs34487581 chr10:897201 G/A cg26597838 chr10:835615 NA 1.47 16.77 0.67 1.78e-46 Eosinophil percentage of granulocytes; LIHC cis rs9640161 0.750 rs11765644 chr7:150026339 C/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.55 -9.2 -0.45 3.66e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs17253792 0.822 rs10147431 chr14:56091841 G/A cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.14 0.55 1.97e-28 Prudent dietary pattern; LIHC cis rs546131 0.928 rs550313 chr11:34830919 C/T cg11058730 chr11:34937778 PDHX;APIP 0.64 9.39 0.45 8.48e-19 Lung disease severity in cystic fibrosis; LIHC cis rs920590 0.642 rs6993525 chr8:19671104 A/G cg01411142 chr8:19674711 INTS10 -0.5 -7.83 -0.39 6.38e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs916888 0.773 rs199534 chr17:44824213 T/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.71 6.77 0.34 5.51e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11958404 0.932 rs11949394 chr5:157425198 A/G cg05962755 chr5:157440814 NA 0.98 10.89 0.51 6.78e-24 IgG glycosylation; LIHC cis rs477895 1.000 rs41294396 chr11:64078581 G/A cg18225595 chr11:63971243 STIP1 0.59 5.75 0.3 1.96e-8 Mean platelet volume; LIHC cis rs13108904 0.936 rs4974540 chr4:1213463 C/T cg05665937 chr4:1216051 CTBP1 0.49 7.25 0.37 2.73e-12 Obesity-related traits; LIHC cis rs9322817 0.535 rs6922070 chr6:105165743 G/A cg02098413 chr6:105308735 HACE1 -0.38 -5.91 -0.3 8.07e-9 Thyroid stimulating hormone; LIHC cis rs2842992 0.724 rs1128670 chr6:160211636 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.14 0.44 5.61e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs875971 0.545 rs67688847 chr7:65626051 G/A cg11764359 chr7:65958608 NA 0.51 7.08 0.36 8.1e-12 Aortic root size; LIHC cis rs1873147 0.569 rs8034365 chr15:63309203 C/T cg21584241 chr15:63341463 TPM1 0.44 6.38 0.33 5.9e-10 Orofacial clefts; LIHC trans rs911555 0.755 rs2273702 chr14:103918182 C/G cg17675199 chr6:35436792 RPL10A -0.41 -8.31 -0.41 2.2e-15 Intelligence (multi-trait analysis); LIHC cis rs7617773 0.778 rs11707997 chr3:48377875 A/G cg11946769 chr3:48343235 NME6 0.93 11.81 0.54 3.03e-27 Coronary artery disease; LIHC trans rs887797 0.704 rs759118 chr17:64547530 C/T cg10016972 chr12:133370462 GOLGA3 -0.42 -6.13 -0.31 2.48e-9 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC cis rs765787 0.530 rs11636404 chr15:45535861 C/G cg25801113 chr15:45476975 SHF 0.38 6.55 0.33 2.1e-10 Uric acid levels; LIHC cis rs7666738 0.785 rs11097614 chr4:99092175 G/C cg05340658 chr4:99064831 C4orf37 0.71 10.77 0.5 1.74e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs9733 0.596 rs6690725 chr1:150632322 T/C cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg16434002 chr17:42200994 HDAC5 -0.53 -7.75 -0.39 1.04e-13 Total body bone mineral density; LIHC trans rs1814175 0.645 rs1608632 chr11:49967148 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg10755058 chr3:40428713 ENTPD3 0.41 6.99 0.35 1.47e-11 Renal cell carcinoma; LIHC cis rs6088590 1.000 rs2378256 chr20:33292127 G/C cg06115741 chr20:33292138 TP53INP2 0.6 8.61 0.42 2.67e-16 Coronary artery disease; LIHC cis rs11077998 0.844 rs8064433 chr17:80501046 A/T cg10255544 chr17:80519551 FOXK2 0.48 8.69 0.43 1.5e-16 Reticulocyte fraction of red cells; LIHC cis rs6076065 0.748 rs2295239 chr20:23387550 C/T cg11657817 chr20:23433608 CST11 0.32 6.71 0.34 7.99e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg11890956 chr21:40555474 PSMG1 0.54 9.07 0.44 9.71e-18 Cognitive function; LIHC cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg12310025 chr6:25882481 NA 0.59 7.96 0.4 2.5e-14 Blood metabolite levels; LIHC cis rs1865760 0.566 rs2032445 chr6:26044812 T/A cg17691542 chr6:26056736 HIST1H1C 0.4 5.79 0.3 1.6e-8 Height; LIHC cis rs763121 0.853 rs2072795 chr22:39064209 A/G cg14440974 chr22:39074834 NA 0.45 7.28 0.37 2.3e-12 Menopause (age at onset); LIHC cis rs10911232 0.507 rs10797817 chr1:182999136 G/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.33 0.49 5.83e-22 Hypertriglyceridemia; LIHC trans rs60843830 1.000 rs6709534 chr2:217334 G/C cg11347411 chr7:150020925 ACTR3C;LRRC61 0.59 8.34 0.41 1.84e-15 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2839186 0.770 rs2839984 chr21:47671690 A/G cg13126279 chr21:47581558 C21orf56 -0.47 -7.68 -0.38 1.66e-13 Testicular germ cell tumor; LIHC cis rs2204008 0.537 rs28680519 chr12:38502946 C/T cg13010199 chr12:38710504 ALG10B 0.53 6.18 0.32 1.79e-9 Bladder cancer; LIHC cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs919433 0.713 rs6719483 chr2:198472886 A/G cg03934865 chr2:198174659 NA 0.52 8.04 0.4 1.51e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1801251 1.000 rs991873 chr2:233711046 A/G cg08000102 chr2:233561755 GIGYF2 -0.76 -11.51 -0.53 3.98e-26 Coronary artery disease; LIHC cis rs2637266 0.783 rs846597 chr10:78529114 A/G cg18941641 chr10:78392320 NA 0.28 6.06 0.31 3.66e-9 Pulmonary function; LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.97 -0.31 6.04e-9 Menopause (age at onset); LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg07677032 chr17:61819896 STRADA 0.44 6.43 0.33 4.24e-10 Prudent dietary pattern; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05514743 chr19:14629124 DNAJB1 -0.53 -6.08 -0.31 3.26e-9 Systolic blood pressure; LIHC cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -11.15 -0.52 7.8e-25 Platelet count; LIHC cis rs2228479 0.702 rs12600151 chr16:89831558 C/T cg19635926 chr16:89946313 TCF25 0.48 6.17 0.32 1.97e-9 Skin colour saturation; LIHC cis rs2404602 0.591 rs11635162 chr15:76951105 C/T cg03037974 chr15:76606532 NA -0.51 -8.09 -0.4 1.07e-14 Blood metabolite levels; LIHC cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg15691649 chr6:25882328 NA -0.46 -6.07 -0.31 3.47e-9 Intelligence (multi-trait analysis); LIHC cis rs8072100 0.967 rs9894905 chr17:45485982 C/T cg08085267 chr17:45401833 C17orf57 -0.59 -8.94 -0.44 2.51e-17 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs9733 0.680 rs3738484 chr1:150552330 G/T cg13175981 chr1:150552382 MCL1 0.61 9.51 0.46 3.62e-19 Tonsillectomy; LIHC cis rs7551222 0.749 rs6682208 chr1:204566183 T/C cg20240347 chr1:204465584 NA -0.31 -6.35 -0.32 7.01e-10 Schizophrenia; LIHC cis rs7618501 0.521 rs952594 chr3:49908023 G/A cg05623727 chr3:50126028 RBM5 0.37 6.16 0.32 2.06e-9 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.669 rs12441484 chr15:77109875 G/A cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.7e-9 Blood metabolite levels; LIHC cis rs9381040 0.610 rs2057002 chr6:41022962 G/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.18 -0.32 1.87e-9 Alzheimer's disease (late onset); LIHC cis rs3770081 1.000 rs3770081 chr2:86280925 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -8.74 -0.43 1.08e-16 Facial emotion recognition (sad faces); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23361579 chr13:114087964 ADPRHL1 0.4 6.22 0.32 1.42e-9 Longevity; LIHC cis rs7818688 0.697 rs76631135 chr8:95980988 G/T cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs10845606 0.505 rs2417221 chr12:12829914 C/T cg09462578 chr12:12878428 APOLD1 0.44 6.76 0.34 5.8200000000000003e-11 Systemic lupus erythematosus; LIHC trans rs1005277 0.522 rs9417256 chr10:37976990 A/G cg23533926 chr12:111358616 MYL2 -0.33 -6.5 -0.33 2.81e-10 Extrinsic epigenetic age acceleration; LIHC cis rs12477438 0.501 rs13033012 chr2:99795149 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs782590 0.967 rs782588 chr2:55841640 T/C cg18811423 chr2:55921094 PNPT1 0.99 15.84 0.65 8.78e-43 Metabolic syndrome; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01585758 chr2:203102753 SUMO1 0.39 6.17 0.32 1.96e-9 Cognitive function; LIHC cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.94 0.31 6.93e-9 Aortic root size; LIHC cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg09417038 chr21:47716443 C21orf57 -0.54 -8.07 -0.4 1.19e-14 Testicular germ cell tumor; LIHC cis rs9911578 1.000 rs9892795 chr17:57023054 G/C cg12560992 chr17:57184187 TRIM37 0.98 17.79 0.69 1.4e-50 Intelligence (multi-trait analysis); LIHC cis rs7188697 0.922 rs4471670 chr16:58601365 G/A cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs6939532 0.517 rs733528 chr6:26374903 A/G cg14345882 chr6:26364793 BTN3A2 0.4 6.07 0.31 3.43e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs1348850 0.526 rs10497504 chr2:178370040 T/C cg27490568 chr2:178487706 NA 1.11 12.06 0.55 3.7e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs9951602 0.512 rs7237214 chr18:76657394 C/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.36 0.49 4.64e-22 Obesity-related traits; LIHC cis rs262150 0.731 rs2657388 chr7:158763428 A/G cg27247782 chr7:158767135 NA 0.37 7.02 0.35 1.23e-11 Facial morphology (factor 20); LIHC cis rs2370759 1.000 rs11594963 chr10:32625736 G/A cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs4713118 0.662 rs9380046 chr6:28030499 T/C cg16479474 chr6:28041457 NA 0.48 7.19 0.36 4.12e-12 Parkinson's disease; LIHC cis rs2836950 0.545 rs2836952 chr21:40616651 G/C cg06238570 chr21:40685208 BRWD1 -0.43 -6.89 -0.35 2.7e-11 Menarche (age at onset); LIHC cis rs6952808 0.771 rs10244946 chr7:1921068 A/G cg14004847 chr7:1930337 MAD1L1 0.53 7.83 0.39 6.24e-14 Bipolar disorder and schizophrenia; LIHC cis rs12701220 0.655 rs7799656 chr7:1140515 C/T cg09177884 chr7:1199841 ZFAND2A -0.53 -6.24 -0.32 1.29e-9 Bronchopulmonary dysplasia; LIHC cis rs9399135 0.967 rs6923765 chr6:135335176 C/G cg22676075 chr6:135203613 NA -0.42 -6.56 -0.33 2.05e-10 Red blood cell count; LIHC cis rs35110281 0.755 rs4819270 chr21:45020919 G/A cg21573476 chr21:45109991 RRP1B -0.57 -10.79 -0.5 1.51e-23 Mean corpuscular volume; LIHC cis rs1577917 0.682 rs6909767 chr6:86228109 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.56 0.33 1.99e-10 Response to antipsychotic treatment; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg27310827 chr1:1163671 SDF4 -0.42 -6.59 -0.34 1.64e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg11060661 chr22:24314208 DDT;DDTL 0.61 10.44 0.49 2.53e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs798554 0.959 rs798528 chr7:2772431 A/C cg19346786 chr7:2764209 NA -0.46 -7.05 -0.36 1.01e-11 Height; LIHC cis rs9916302 0.821 rs12938268 chr17:37572139 G/A cg00129232 chr17:37814104 STARD3 -0.41 -6.49 -0.33 2.95e-10 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.626 rs11228279 chr11:68309680 C/T cg20283391 chr11:68216788 NA 0.38 6.11 0.31 2.72e-9 Total body bone mineral density; LIHC cis rs1577917 1.000 rs34852683 chr6:86702330 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.63 -0.46 1.43e-19 Response to antipsychotic treatment; LIHC cis rs9733 0.566 rs72702554 chr1:150678234 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.06e-9 Tonsillectomy; LIHC cis rs1552244 1.000 rs7626117 chr3:10140671 G/A cg13047869 chr3:10149882 C3orf24 0.48 6.44 0.33 4.02e-10 Alzheimer's disease; LIHC cis rs7172677 0.731 rs1108059 chr15:75338890 A/C cg09165964 chr15:75287851 SCAMP5 0.5 7.0 0.35 1.32e-11 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs950169 0.544 rs12913702 chr15:85153184 G/A cg12863693 chr15:85201151 NMB 0.43 6.01 0.31 4.71e-9 Schizophrenia; LIHC cis rs10733682 0.659 rs1887970 chr9:129464827 C/T cg00232160 chr9:129468157 NA 0.35 6.06 0.31 3.68e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4319547 1.000 rs10998 chr12:122989412 G/A cg05707623 chr12:122985044 ZCCHC8 -0.62 -8.18 -0.4 5.74e-15 Body mass index; LIHC cis rs11098499 0.863 rs3775843 chr4:120427844 T/C cg09307838 chr4:120376055 NA 0.77 11.99 0.54 7.12e-28 Corneal astigmatism; LIHC cis rs875971 0.825 rs801202 chr7:66023929 C/T cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.28e-34 Aortic root size; LIHC cis rs9902453 1.000 rs55971458 chr17:28427016 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.62 9.49 0.46 4.13e-19 Coffee consumption (cups per day); LIHC cis rs7927771 0.524 rs7122182 chr11:47843133 A/C cg20307385 chr11:47447363 PSMC3 -0.66 -9.97 -0.47 1.01e-20 Subjective well-being; LIHC cis rs9814567 0.806 rs2293294 chr3:134322814 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.59 9.55 0.46 2.66e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg05185784 chr16:90016020 DEF8 -0.52 -6.58 -0.34 1.79e-10 Skin colour saturation; LIHC cis rs12824058 0.831 rs11060826 chr12:130809931 G/C cg24838063 chr12:130822603 PIWIL1 0.67 9.96 0.47 1.1e-20 Menopause (age at onset); LIHC cis rs2370759 1.000 rs79806114 chr10:32618022 T/C cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs2625529 0.824 rs4777470 chr15:72207518 T/A cg16672083 chr15:72433130 SENP8 -0.31 -5.87 -0.3 1.02e-8 Red blood cell count; LIHC cis rs420259 0.549 rs40076 chr16:23692405 A/G cg05131483 chr16:23706242 ERN2 0.37 6.01 0.31 4.88e-9 Bipolar disorder; LIHC cis rs28655083 0.828 rs7404322 chr16:77130003 G/A cg09454613 chr16:77233327 SYCE1L;MON1B -0.4 -6.16 -0.32 2.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg19635926 chr16:89946313 TCF25 0.54 7.03 0.36 1.11e-11 Skin colour saturation; LIHC cis rs8141529 0.843 rs1065497 chr22:29279991 C/T cg15103426 chr22:29168792 CCDC117 0.57 9.12 0.44 6.41e-18 Lymphocyte counts; LIHC cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg25894440 chr7:65020034 NA 0.53 6.14 0.31 2.32e-9 Diabetic kidney disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27313007 chr17:78617750 RPTOR 0.43 6.52 0.33 2.5e-10 Longevity; LIHC cis rs2108622 0.727 rs7256877 chr19:15980683 T/C cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs4819052 0.885 rs9980676 chr21:46665430 A/G cg11663144 chr21:46675770 NA -0.32 -5.94 -0.31 7.16e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9381040 0.610 rs9381028 chr6:41025081 C/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.02 -0.31 4.41e-9 Alzheimer's disease (late onset); LIHC cis rs2836974 0.565 rs2836939 chr21:40578546 C/T cg11644478 chr21:40555479 PSMG1 0.72 6.69 0.34 9.13e-11 Cognitive function; LIHC cis rs2607426 1.000 rs2607421 chr19:41277077 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.49 -5.88 -0.3 9.77e-9 Blood protein levels; LIHC trans rs3749237 0.964 rs13084243 chr3:49821878 G/C cg21659725 chr3:3221576 CRBN 0.8 12.39 0.56 2.21e-29 Resting heart rate; LIHC trans rs11039798 0.588 rs61932767 chr11:48704806 C/T cg15704280 chr7:45808275 SEPT13 0.59 6.75 0.34 6.23e-11 Axial length; LIHC trans rs8117834 0.574 rs6086329 chr20:8082061 T/C cg00593689 chr4:53575888 NA 0.38 6.5 0.33 2.77e-10 Chronic kidney disease; LIHC cis rs6449957 0.639 rs251398 chr5:67509801 C/T cg23036683 chr5:67512108 NA -0.52 -7.68 -0.38 1.74e-13 Cleft lip with or without cleft palate; LIHC cis rs4919087 1.000 rs10786333 chr10:99090390 A/G cg25902810 chr10:99078978 FRAT1 -0.66 -9.91 -0.47 1.63e-20 Monocyte count; LIHC cis rs2197308 0.765 rs11182434 chr12:37923968 C/A cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC trans rs11098499 0.955 rs13113112 chr4:120156040 C/T cg25214090 chr10:38739885 LOC399744 0.54 8.2 0.41 4.76e-15 Corneal astigmatism; LIHC cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg24884572 chr19:58661833 ZNF329 0.98 7.71 0.38 1.36e-13 Cholesterol, total; LIHC cis rs2228479 0.850 rs17226428 chr16:89842884 T/A cg06558623 chr16:89946397 TCF25 0.87 11.66 0.53 1.1e-26 Skin colour saturation; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07383130 chr1:16161673 FLJ37453 0.48 6.67 0.34 1.01e-10 Hepatitis; LIHC cis rs5769707 0.632 rs6009782 chr22:50010812 C/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.68 -0.42 1.63e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6500602 0.893 rs6500598 chr16:4470964 G/T cg08645402 chr16:4508243 NA 0.34 5.83 0.3 1.26e-8 Schizophrenia; LIHC cis rs929354 0.742 rs7785227 chr7:156999297 C/T cg16102536 chr7:156981717 UBE3C 0.35 5.85 0.3 1.17e-8 Body mass index; LIHC cis rs11583043 0.918 rs56402739 chr1:101397133 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.3 0.32 8.96e-10 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1878931 0.507 rs4429296 chr16:3408277 T/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.65 -8.57 -0.42 3.58e-16 Body mass index (adult); LIHC cis rs12824058 0.831 rs1390849 chr12:130811547 A/G cg26677194 chr12:130822605 PIWIL1 0.52 7.36 0.37 1.36e-12 Menopause (age at onset); LIHC cis rs2075371 1.000 rs447266 chr7:133989543 A/G cg11752832 chr7:134001865 SLC35B4 0.52 7.75 0.39 1.04e-13 Mean platelet volume; LIHC cis rs17685 0.753 rs1637037 chr7:75692927 C/T cg04592579 chr7:75616294 TMEM120A 0.4 7.0 0.35 1.32e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg13395646 chr4:1353034 KIAA1530 -0.41 -5.8 -0.3 1.48e-8 Longevity; LIHC cis rs7091068 0.671 rs604489 chr10:95405408 T/C cg20715218 chr10:95462985 C10orf4 -0.6 -6.87 -0.35 3.04e-11 Urinary tract infection frequency; LIHC cis rs5758511 0.514 rs5758580 chr22:42493875 T/C cg20195005 chr22:42527684 CYP2D6 0.31 5.89 0.3 9.03e-9 Birth weight; LIHC cis rs1008375 1.000 rs2286771 chr4:17643848 G/A cg16339924 chr4:17578868 LAP3 0.44 6.19 0.32 1.68e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17331151 0.573 rs2276818 chr3:52864635 A/G cg04865290 chr3:52927548 TMEM110 -0.42 -6.34 -0.32 7.28e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs727563 0.565 rs132774 chr22:42031953 C/G cg03806693 chr22:41940476 POLR3H -0.62 -6.86 -0.35 3.28e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs854765 0.647 rs4365346 chr17:17989373 G/T cg04398451 chr17:18023971 MYO15A -0.66 -10.94 -0.51 4.39e-24 Total body bone mineral density; LIHC cis rs769267 0.965 rs2965188 chr19:19522557 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.06 0.4 1.29e-14 Tonsillectomy; LIHC cis rs28830936 1.000 rs12441300 chr15:42102845 A/G cg17847044 chr15:42102381 MAPKBP1 -0.32 -6.36 -0.33 6.45e-10 Diastolic blood pressure; LIHC cis rs875971 1.000 rs875971 chr7:65617595 A/G cg18876405 chr7:65276391 NA -0.37 -6.65 -0.34 1.19e-10 Aortic root size; LIHC trans rs116095464 0.558 rs9312977 chr5:221916 G/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg22907277 chr7:1156413 C7orf50 0.76 5.95 0.31 6.71e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg10802521 chr3:52805072 NEK4 -0.45 -7.7 -0.38 1.45e-13 Electroencephalogram traits; LIHC cis rs459571 0.959 rs2073818 chr9:136918662 C/A cg13789015 chr9:136890014 NCRNA00094 0.44 7.86 0.39 5.13e-14 Platelet distribution width; LIHC trans rs2243480 0.901 rs35087093 chr7:65405208 C/T cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs2795502 0.882 rs2744091 chr10:43339441 A/G cg27426351 chr10:43362370 NA -0.46 -5.74 -0.3 2.11e-8 Blood protein levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16803707 chr20:1099736 PSMF1 0.47 6.35 0.32 6.94e-10 Pancreatic cancer; LIHC cis rs6964587 0.755 rs13229505 chr7:91444679 G/T cg17063962 chr7:91808500 NA 0.96 17.56 0.69 1.12e-49 Breast cancer; LIHC cis rs1401999 0.807 rs9869029 chr3:183735286 C/G cg20387954 chr3:183756860 HTR3D 0.29 6.17 0.32 1.9e-9 Anterior chamber depth; LIHC cis rs4853525 0.522 rs1860167 chr2:191582387 G/A cg05765582 chr2:191677683 NA 0.3 5.72 0.3 2.3e-8 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs3790645 1.000 rs3127013 chr1:26891360 T/G cg17456097 chr1:26900765 RPS6KA1 0.41 5.9 0.3 8.96e-9 Glucose homeostasis traits; LIHC cis rs6120849 0.754 rs6120804 chr20:33623701 C/A cg24642439 chr20:33292090 TP53INP2 0.65 7.05 0.36 9.65e-12 Protein C levels; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg27141850 chr2:20869434 GDF7 0.33 6.73 0.34 7.15e-11 Abdominal aortic aneurysm; LIHC cis rs798554 0.836 rs798526 chr7:2775542 G/C cg13628971 chr7:2884303 GNA12 0.52 7.68 0.38 1.71e-13 Height; LIHC cis rs7520050 0.966 rs4376778 chr1:46288846 C/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.75 0.3 2.03e-8 Red blood cell count;Reticulocyte count; LIHC cis rs116095464 1.000 rs6555160 chr5:311669 A/G cg22857025 chr5:266934 NA 1.08 7.25 0.37 2.79e-12 Breast cancer; LIHC cis rs6089584 0.893 rs2281735 chr20:60582540 T/A cg12751644 chr20:60527061 NA -0.36 -6.06 -0.31 3.61e-9 Body mass index; LIHC cis rs875971 0.660 rs801217 chr7:66010577 C/T cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC cis rs4665809 0.938 rs4665822 chr2:26312555 C/G cg27170947 chr2:26402098 FAM59B -0.62 -7.71 -0.38 1.37e-13 Gut microbiome composition (summer); LIHC cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg27572855 chr1:25598939 RHD 0.39 8.28 0.41 2.83e-15 Erythrocyte sedimentation rate; LIHC cis rs9911578 1.000 rs2531732 chr17:56548420 T/A cg12560992 chr17:57184187 TRIM37 -0.96 -17.16 -0.68 4.62e-48 Intelligence (multi-trait analysis); LIHC cis rs3823572 0.564 rs2953621 chr7:133662403 C/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.71 -0.3 2.46e-8 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg07677032 chr17:61819896 STRADA 0.43 6.25 0.32 1.23e-9 Prudent dietary pattern; LIHC cis rs3770081 1.000 rs75038217 chr2:86348025 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -7.75 -0.39 1.08e-13 Facial emotion recognition (sad faces); LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg06873352 chr17:61820015 STRADA 0.53 7.83 0.39 6.05e-14 Height; LIHC cis rs9394841 0.667 rs1891453 chr6:41765265 T/C cg08135965 chr6:41755394 TOMM6 0.44 5.72 0.3 2.34e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg04571941 chr7:5463284 TNRC18 -0.43 -6.05 -0.31 3.81e-9 Alopecia areata; LIHC cis rs769267 1.000 rs12985655 chr19:19442434 G/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.27 -0.32 1.11e-9 Tonsillectomy; LIHC cis rs6964587 1.000 rs6960867 chr7:91712698 A/G cg17063962 chr7:91808500 NA 0.96 17.51 0.69 1.9e-49 Breast cancer; LIHC trans rs1814175 0.817 rs12287396 chr11:49819798 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.77 0.34 5.69e-11 Height; LIHC cis rs7818688 0.697 rs80217195 chr8:95986853 T/C cg16049864 chr8:95962084 TP53INP1 0.59 6.42 0.33 4.5e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs11122272 0.766 rs2790867 chr1:231548059 A/C cg06096015 chr1:231504339 EGLN1 -0.51 -9.36 -0.45 1.06e-18 Hemoglobin concentration; LIHC cis rs986417 0.901 rs2351171 chr14:61000322 T/C cg27398547 chr14:60952738 C14orf39 0.74 8.04 0.4 1.46e-14 Gut microbiota (bacterial taxa); LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.22 0.55 9.92e-29 Prudent dietary pattern; LIHC cis rs9300255 0.602 rs1617434 chr12:123649486 A/G cg00376283 chr12:123451042 ABCB9 0.65 7.04 0.36 1.06e-11 Neutrophil percentage of white cells; LIHC cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg07424592 chr7:64974309 NA 0.8 9.41 0.45 7.59e-19 Diabetic kidney disease; LIHC cis rs898097 0.607 rs2199111 chr17:80823203 A/G cg02711726 chr17:80685570 FN3KRP 0.32 5.81 0.3 1.41e-8 Breast cancer; LIHC cis rs2204008 0.837 rs1842599 chr12:37986081 G/A cg26384229 chr12:38710491 ALG10B -0.5 -6.84 -0.35 3.73e-11 Bladder cancer; LIHC cis rs11676348 0.818 rs7426289 chr2:218966315 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.1 -0.31 2.87e-9 Ulcerative colitis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03212183 chr16:81565917 CMIP 0.43 6.53 0.33 2.44e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9733 0.596 rs6681990 chr1:150695929 A/G cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg18306943 chr3:40428807 ENTPD3 -0.42 -7.43 -0.37 8.54e-13 Renal cell carcinoma; LIHC cis rs7552404 1.000 rs6593585 chr1:76140273 G/A cg22875332 chr1:76189707 ACADM 0.48 7.21 0.36 3.61e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs523522 0.923 rs2235217 chr12:120884328 C/T cg12219531 chr12:120966889 COQ5 0.65 12.48 0.56 1.02e-29 High light scatter reticulocyte count; LIHC cis rs35110281 0.805 rs2838330 chr21:45023876 T/A cg01579765 chr21:45077557 HSF2BP -0.32 -6.07 -0.31 3.44e-9 Mean corpuscular volume; LIHC cis rs2228479 0.850 rs76075456 chr16:89834270 T/C cg04013166 chr16:89971882 TCF25 0.52 6.46 0.33 3.55e-10 Skin colour saturation; LIHC cis rs826838 0.616 rs10880751 chr12:38627485 C/T cg26384229 chr12:38710491 ALG10B 0.5 7.1 0.36 7.33e-12 Heart rate; LIHC cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg22633049 chr21:46681294 NA -0.38 -6.5 -0.33 2.91e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12602486 1.000 rs76926880 chr17:42247377 C/G cg13607699 chr17:42295918 UBTF -0.75 -6.42 -0.33 4.46e-10 Glycated hemoglobin levels; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.76 0.39 1e-13 Prudent dietary pattern; LIHC cis rs7927592 0.913 rs7107622 chr11:68374183 T/C cg20283391 chr11:68216788 NA -0.51 -7.53 -0.38 4.48e-13 Total body bone mineral density; LIHC cis rs892961 0.867 rs1079354 chr17:75415713 C/T cg05865280 chr17:75406074 SEPT9 0.62 11.48 0.53 4.92e-26 Airflow obstruction; LIHC cis rs4665809 1.000 rs12471809 chr2:26307140 A/G cg04944784 chr2:26401820 FAM59B -0.65 -8.29 -0.41 2.58e-15 Gut microbiome composition (summer); LIHC cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg18404041 chr3:52824283 ITIH1 -0.55 -9.21 -0.45 3.3e-18 Electroencephalogram traits; LIHC cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg23978390 chr7:1156363 C7orf50 0.55 8.05 0.4 1.41e-14 Longevity;Endometriosis; LIHC cis rs8072100 0.840 rs9895746 chr17:45479099 C/A cg08085267 chr17:45401833 C17orf57 -0.55 -8.24 -0.41 3.6e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs4332037 0.539 rs11764780 chr7:2020904 G/C cg11693508 chr17:37793320 STARD3 0.68 6.88 0.35 2.81e-11 Bipolar disorder; LIHC cis rs2777491 0.872 rs7176588 chr15:41588872 C/T cg18705301 chr15:41695430 NDUFAF1 -0.56 -8.41 -0.41 1.09e-15 Ulcerative colitis; LIHC trans rs11722228 0.549 rs3796818 chr4:10097976 C/T cg26043149 chr18:55253948 FECH 0.97 13.95 0.6 2.52e-35 Gout;Urate levels;Serum uric acid levels; LIHC trans rs9302065 0.565 rs2993585 chr13:95961966 G/A cg19955956 chr7:72299837 SBDSP;TYW1B 0.35 6.48 0.33 3.24e-10 Blood metabolite levels; LIHC trans rs8020941 0.585 rs77608728 chr14:97519423 G/A cg18504190 chr11:1649947 HCCA2;KRTAP5-5 0.46 6.04 0.31 3.92e-9 Diabetic kidney disease; LIHC cis rs10751667 0.666 rs7396677 chr11:958878 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.08 0.48 4.28e-21 Alzheimer's disease (late onset); LIHC trans rs35110281 0.782 rs2246602 chr21:45064296 C/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.19 0.32 1.76e-9 Mean corpuscular volume; LIHC cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs2204008 0.805 rs11179579 chr12:38213957 A/C cg26384229 chr12:38710491 ALG10B 0.82 10.25 0.48 1.14e-21 Bladder cancer; LIHC cis rs897984 0.644 rs73524556 chr16:30823162 G/A cg00531865 chr16:30841666 NA -0.37 -5.98 -0.31 5.49e-9 Dementia with Lewy bodies; LIHC cis rs644799 1.000 rs644799 chr11:95564259 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.54 0.46 2.9e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg13126279 chr21:47581558 C21orf56 -0.47 -7.71 -0.38 1.35e-13 Testicular germ cell tumor; LIHC cis rs2439831 0.867 rs12443102 chr15:43932103 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.11 0.44 7.21e-18 Lung cancer in ever smokers; LIHC cis rs17539620 0.534 rs76931320 chr6:154833508 G/A cg17771515 chr6:154831774 CNKSR3 0.59 6.15 0.32 2.17e-9 Lipoprotein (a) levels; LIHC cis rs35150201 1.000 rs35150201 chr7:135346262 T/G cg23117316 chr7:135346802 PL-5283 -0.3 -6.46 -0.33 3.65e-10 Plateletcrit;Mean corpuscular hemoglobin;Mean platelet volume; LIHC cis rs7927771 1.000 rs4752797 chr11:47874364 C/T cg20307385 chr11:47447363 PSMC3 -0.44 -5.78 -0.3 1.65e-8 Subjective well-being; LIHC cis rs10419226 0.809 rs8102046 chr19:18795578 T/G cg16673477 chr19:18812017 CRTC1 -0.36 -5.94 -0.31 6.86e-9 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs67460515 0.563 rs9883566 chr3:160770323 C/T cg17135325 chr3:160939158 NMD3 -0.5 -6.95 -0.35 1.82e-11 Parkinson's disease; LIHC cis rs7116495 1.000 rs564170 chr11:71569979 T/C cg26138937 chr11:71823887 C11orf51 0.68 6.63 0.34 1.3100000000000001e-10 Severe influenza A (H1N1) infection; LIHC cis rs35110281 0.627 rs11701746 chr21:44975137 C/T cg01579765 chr21:45077557 HSF2BP -0.33 -6.18 -0.32 1.79e-9 Mean corpuscular volume; LIHC cis rs4820294 0.669 rs732857 chr22:38060850 C/T cg00142150 chr22:38071001 LGALS1 0.45 7.55 0.38 4.08e-13 Fat distribution (HIV); LIHC cis rs7267979 0.966 rs2257233 chr20:25265984 A/C cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.78 -0.34 5.34e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs765787 0.530 rs1706832 chr15:45517173 C/T cg24006582 chr15:45444508 DUOX1 -0.54 -7.81 -0.39 7.14e-14 Uric acid levels; LIHC cis rs1865760 0.929 rs2876693 chr6:25954434 C/G cg03517284 chr6:25882590 NA -0.41 -6.2 -0.32 1.63e-9 Height; LIHC cis rs6500602 0.702 rs1051308 chr16:4560301 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 -0.44 -5.93 -0.31 7.26e-9 Schizophrenia; LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.88 -0.3 9.68e-9 Total body bone mineral density; LIHC cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg16325326 chr1:53192061 ZYG11B -0.41 -6.98 -0.35 1.51e-11 Monocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17396978 chr15:57210912 TCF12;LOC145783 0.46 6.27 0.32 1.1e-9 Lung function (FEV1/FVC); LIHC cis rs4934494 0.768 rs7078321 chr10:91438098 C/T cg19698084 chr10:91461284 KIF20B -0.49 -6.49 -0.33 2.93e-10 Red blood cell count; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg00958676 chr8:9911641 MSRA -0.61 -6.67 -0.34 1.01e-10 Preeclampsia; LIHC cis rs11628318 0.614 rs7155489 chr14:103123119 C/T cg23461800 chr14:103021989 NA 0.44 5.95 0.31 6.67e-9 Platelet count; LIHC cis rs12928939 0.769 rs34680964 chr16:71658594 G/A cg03805757 chr16:71968109 PKD1L3 -0.56 -6.3 -0.32 9.05e-10 Post bronchodilator FEV1; LIHC cis rs7572733 0.555 rs700671 chr2:198690001 T/C cg10820045 chr2:198174542 NA 0.45 6.82 0.35 4.18e-11 Dermatomyositis; LIHC cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg24531977 chr5:56204891 C5orf35 -0.65 -9.37 -0.45 1.02e-18 Initial pursuit acceleration; LIHC cis rs1552244 0.882 rs13077641 chr3:10022935 G/A cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs6748734 1.000 rs3936203 chr2:241834654 C/T cg20140201 chr2:241835670 C2orf54 0.46 6.11 0.31 2.73e-9 Urinary metabolites; LIHC cis rs826838 0.872 rs826878 chr12:39088837 A/T cg13010199 chr12:38710504 ALG10B -0.38 -5.95 -0.31 6.82e-9 Heart rate; LIHC cis rs6840360 0.533 rs4696297 chr4:152725838 T/G cg22705602 chr4:152727874 NA 0.39 8.32 0.41 2.19e-15 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.811 rs1122873 chr21:45044672 G/C cg04455712 chr21:45112962 RRP1B 0.45 7.69 0.38 1.58e-13 Mean corpuscular volume; LIHC cis rs3008870 0.701 rs2815358 chr1:67493778 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.65 11.09 0.51 1.23e-24 Lymphocyte percentage of white cells; LIHC cis rs9309473 1.000 rs7598396 chr2:73652628 A/G cg20560298 chr2:73613845 ALMS1 -0.57 -7.02 -0.36 1.18e-11 Metabolite levels; LIHC cis rs6952808 0.529 rs73038442 chr7:2139457 C/T cg04267008 chr7:1944627 MAD1L1 -0.53 -8.35 -0.41 1.68e-15 Bipolar disorder and schizophrenia; LIHC cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg12311346 chr5:56204834 C5orf35 0.57 7.5 0.38 5.51e-13 Initial pursuit acceleration; LIHC trans rs7121800 0.962 rs11031119 chr11:30525773 A/G cg03935116 chr12:31476565 FAM60A;FLJ13224 0.28 6.06 0.31 3.57e-9 Pit-and-Fissure caries; LIHC cis rs8067354 0.540 rs7221472 chr17:58036737 C/T cg13753209 chr17:57696993 CLTC 0.71 10.58 0.5 8.01e-23 Hemoglobin concentration; LIHC cis rs1873147 0.569 rs58819603 chr15:63310866 T/A cg21584241 chr15:63341463 TPM1 0.44 6.38 0.33 5.9e-10 Orofacial clefts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05470809 chr4:175205489 KIAA1712;FBXO8 0.52 7.25 0.36 2.73e-12 Pancreatic cancer; LIHC cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg17990871 chr1:1677678 SLC35E2 -0.36 -5.74 -0.3 2.11e-8 Body mass index; LIHC cis rs6964587 0.967 rs2188153 chr7:91595117 G/T cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC cis rs17106184 1.000 rs80326064 chr1:51240851 C/T cg07174182 chr1:51127561 FAF1 -0.61 -6.65 -0.34 1.18e-10 Type 2 diabetes; LIHC cis rs4805272 0.539 rs1422212 chr19:29330191 T/A cg04546413 chr19:29218101 NA 0.41 6.6 0.34 1.53e-10 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs7927592 0.956 rs11228256 chr11:68251460 G/A cg20283391 chr11:68216788 NA -0.51 -7.55 -0.38 3.93e-13 Total body bone mineral density; LIHC trans rs792448 0.743 rs351386 chr1:212421771 C/T cg20223728 chr6:6006398 NRN1 0.35 6.17 0.32 1.95e-9 White blood cell count (basophil); LIHC cis rs6732160 0.691 rs4536673 chr2:73413462 A/T cg24220031 chr2:73402428 NA -0.28 -6.06 -0.31 3.54e-9 Intelligence (multi-trait analysis); LIHC cis rs7587476 0.906 rs2070096 chr2:215645545 C/G cg04004882 chr2:215674386 BARD1 0.51 6.27 0.32 1.11e-9 Neuroblastoma; LIHC cis rs7833790 0.660 rs67666182 chr8:82772037 A/G cg27398817 chr8:82754497 SNX16 0.31 5.75 0.3 1.99e-8 Diastolic blood pressure; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00098280 chr18:29523426 KIAA1012 -0.53 -6.66 -0.34 1.11e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7116495 0.609 rs7113436 chr11:71689599 A/T cg26138937 chr11:71823887 C11orf51 1.3 10.45 0.49 2.25e-22 Severe influenza A (H1N1) infection; LIHC cis rs11951515 0.508 rs6860493 chr5:43602713 T/C cg01983248 chr5:43482804 C5orf28 -0.4 -6.49 -0.33 2.93e-10 Metabolite levels (X-11787); LIHC cis rs9399135 0.967 rs9389256 chr6:135331254 A/C cg22676075 chr6:135203613 NA 0.38 6.17 0.32 1.93e-9 Red blood cell count; LIHC cis rs7552404 0.727 rs2172507 chr1:76331320 A/G cg03433033 chr1:76189801 ACADM -0.55 -7.11 -0.36 6.77e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs748404 0.586 rs2584700 chr15:43685332 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.53 8.21 0.41 4.72e-15 Lung cancer; LIHC cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg03060546 chr3:49711283 APEH 0.4 5.97 0.31 5.87e-9 Menarche (age at onset); LIHC cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg08280861 chr8:58055591 NA 0.53 6.46 0.33 3.66e-10 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.6 5.86 0.3 1.11e-8 Platelet count; LIHC cis rs10752881 0.967 rs4652758 chr1:182975100 T/C ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg24503407 chr1:205819492 PM20D1 0.86 12.6 0.56 3.61e-30 Menarche (age at onset); LIHC cis rs6952808 0.929 rs1801368 chr7:1976457 C/T cg02951883 chr7:2050386 MAD1L1 -0.66 -10.38 -0.49 4.15e-22 Bipolar disorder and schizophrenia; LIHC cis rs3617 0.625 rs11922961 chr3:52868610 T/C cg11645453 chr3:52864694 ITIH4 -0.22 -5.86 -0.3 1.08e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs7927592 0.913 rs12294029 chr11:68257059 A/C cg16797656 chr11:68205561 LRP5 0.53 8.44 0.42 8.82e-16 Total body bone mineral density; LIHC cis rs35110281 0.720 rs162372 chr21:44928863 C/T cg04455712 chr21:45112962 RRP1B -0.47 -7.62 -0.38 2.49e-13 Mean corpuscular volume; LIHC cis rs7005606 0.532 rs1579033 chr8:32298180 C/G cg16623836 chr8:32453385 NRG1 -0.35 -5.81 -0.3 1.4e-8 Hirschsprung disease; LIHC cis rs1707322 0.686 rs2991977 chr1:46053683 G/A cg06784218 chr1:46089804 CCDC17 -0.4 -7.19 -0.36 4.23e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2617583 0.935 rs1354139 chr5:1451782 T/C cg07151155 chr5:1473589 LPCAT1 -0.41 -6.21 -0.32 1.51e-9 Breast cancer; LIHC cis rs7903847 0.620 rs2297988 chr10:99118382 A/G cg06359132 chr10:99160096 RRP12 -0.38 -5.83 -0.3 1.31e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs963731 0.522 rs297148 chr2:39323166 A/G cg04010122 chr2:39346883 SOS1 -0.68 -6.03 -0.31 4.15e-9 Corticobasal degeneration; LIHC cis rs1577917 1.000 rs12190598 chr6:86686074 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.11 -0.48 3.33e-21 Response to antipsychotic treatment; LIHC trans rs10411161 0.752 rs10402107 chr19:52384600 A/G cg22319618 chr22:45562946 NUP50 -0.59 -8.12 -0.4 8.66e-15 Breast cancer; LIHC cis rs9814567 0.793 rs55940445 chr3:134306064 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.44 6.1 0.31 2.91e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8014671 0.532 rs1953800 chr14:70958696 T/C cg25576086 chr14:70833871 SYNJ2BP 0.45 6.94 0.35 2.03e-11 Prostate cancer; LIHC cis rs61863818 0.709 rs10786343 chr10:99159465 C/A cg08345082 chr10:99160200 RRP12 -0.39 -6.53 -0.33 2.38e-10 Monocyte percentage of white cells; LIHC cis rs7208859 0.614 rs28758251 chr17:29223312 A/T cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1878931 0.582 rs27239 chr16:3442140 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.72 -0.43 1.19e-16 Body mass index (adult); LIHC cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg12463550 chr7:65579703 CRCP -0.66 -6.96 -0.35 1.78e-11 Diabetic kidney disease; LIHC cis rs751728 1.000 rs755496 chr6:33734376 C/G cg25922239 chr6:33757077 LEMD2 0.35 5.71 0.3 2.42e-8 Crohn's disease; LIHC trans rs7613875 0.543 rs34034116 chr3:49959156 C/A cg21659725 chr3:3221576 CRBN 0.56 8.18 0.4 5.53e-15 Body mass index; LIHC cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg14222432 chr12:29376421 FAR2 0.38 7.24 0.36 2.93e-12 QT interval; LIHC trans rs4566357 0.615 rs3769643 chr2:227917270 T/C cg16088116 chr21:44841560 SIK1 -0.42 -6.52 -0.33 2.59e-10 Coronary artery disease; LIHC cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg05754148 chr16:3507555 NAT15 0.41 6.15 0.32 2.16e-9 Tuberculosis; LIHC cis rs67460515 0.892 rs2100238 chr3:161058055 T/A cg17135325 chr3:160939158 NMD3 0.56 8.21 0.41 4.71e-15 Parkinson's disease; LIHC cis rs763121 0.853 rs1062687 chr22:39134715 T/C cg06544989 chr22:39130855 UNC84B 0.4 6.55 0.33 2.12e-10 Menopause (age at onset); LIHC trans rs459571 0.629 rs441233 chr9:136876021 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 0.62 9.96 0.47 1.06e-20 Platelet distribution width; LIHC cis rs10744422 1.000 rs4759355 chr12:123316566 A/G cg07706471 chr12:123319906 HIP1R -0.58 -7.69 -0.38 1.62e-13 Schizophrenia; LIHC cis rs798554 0.797 rs35957220 chr7:2812632 C/G cg04166393 chr7:2884313 GNA12 0.44 6.08 0.31 3.19e-9 Height; LIHC cis rs11758351 0.866 rs55815656 chr6:26207303 G/A cg03854865 chr6:26224070 HIST1H3E 0.62 7.11 0.36 6.65e-12 Gout;Renal underexcretion gout; LIHC cis rs10791323 0.536 rs4937842 chr11:133734542 C/G cg03690763 chr11:133734501 NA 0.21 5.98 0.31 5.7e-9 Childhood ear infection; LIHC cis rs17401966 1.000 rs1049887 chr1:10460485 T/C cg19773385 chr1:10388646 KIF1B -0.48 -7.44 -0.37 8.29e-13 Hepatocellular carcinoma; LIHC cis rs10744422 1.000 rs3852537 chr12:123361501 T/C cg07706471 chr12:123319906 HIP1R -0.59 -7.78 -0.39 8.57e-14 Schizophrenia; LIHC trans rs3749855 0.679 rs13201114 chr6:17265647 G/A cg00118684 chr18:13726609 RNMT;C18orf19 -0.61 -6.08 -0.31 3.12e-9 Glucose homeostasis traits; LIHC cis rs2380220 0.640 rs9320386 chr6:95994955 T/C cg15832292 chr6:96025679 MANEA 0.62 7.17 0.36 4.71e-12 Behavioural disinhibition (generation interaction); LIHC cis rs6088590 1.000 rs6119516 chr20:33328024 C/T cg06115741 chr20:33292138 TP53INP2 0.6 8.64 0.42 2.15e-16 Coronary artery disease; LIHC cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg12379764 chr21:47803548 PCNT -0.59 -8.46 -0.42 7.73e-16 Testicular germ cell tumor; LIHC cis rs13108904 0.934 rs35201724 chr4:1310717 C/G cg19318889 chr4:1322082 MAEA 0.48 6.57 0.33 1.85e-10 Obesity-related traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18350524 chr12:93835624 UBE2N -0.41 -6.1 -0.31 2.84e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9916302 0.904 rs4795356 chr17:37535631 C/T cg03013999 chr17:37608204 MED1 -0.36 -5.91 -0.3 8.4e-9 Glomerular filtration rate (creatinine); LIHC cis rs13217239 0.646 rs7768407 chr6:27016795 G/A cg18867708 chr6:26865862 GUSBL1 0.52 7.87 0.39 4.72e-14 Schizophrenia; LIHC cis rs9640161 0.789 rs13223702 chr7:150058968 G/A cg10018233 chr7:150070692 REPIN1 0.58 8.81 0.43 6.49e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs12479064 0.694 rs4341989 chr2:100046783 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -8.97 -0.44 1.97e-17 Chronic sinus infection; LIHC cis rs17685 0.753 rs1806885 chr7:75785612 T/G cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7572733 0.534 rs1607375 chr2:198800387 C/T cg10820045 chr2:198174542 NA 0.48 7.47 0.37 6.93e-13 Dermatomyositis; LIHC cis rs12579753 0.797 rs1922561 chr12:82152640 C/A cg07988820 chr12:82153109 PPFIA2 -0.48 -5.83 -0.3 1.28e-8 Resting heart rate; LIHC cis rs317689 0.690 rs317656 chr12:69681101 T/A cg14784868 chr12:69753453 YEATS4 0.56 7.93 0.39 3.09e-14 Response to diuretic therapy; LIHC cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Bipolar disorder; LIHC cis rs72781680 1.000 rs72781658 chr2:24220141 A/G cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs155076 1.000 rs261404 chr13:21858162 T/G cg11317459 chr13:21872234 NA -1.09 -12.65 -0.56 2.35e-30 White matter hyperintensity burden; LIHC cis rs910316 0.712 rs175015 chr14:75457075 A/C cg11812906 chr14:75593930 NEK9 -0.75 -13.92 -0.6 3.4000000000000003e-35 Height; LIHC trans rs637571 0.510 rs4930320 chr11:65576788 C/G cg17712092 chr4:129076599 LARP1B -0.7 -10.23 -0.48 1.32e-21 Eosinophil percentage of white cells; LIHC cis rs11758351 1.000 rs3757135 chr6:26200707 G/A cg16070018 chr6:26224392 HIST1H3E 0.55 6.52 0.33 2.6e-10 Gout;Renal underexcretion gout; LIHC cis rs17608059 0.524 rs9897978 chr17:13900256 G/T cg11395062 chr17:14139857 CDRT15 -0.61 -9.96 -0.47 1.08e-20 Temperament; LIHC cis rs7666738 0.830 rs11735193 chr4:98761900 C/T cg05340658 chr4:99064831 C4orf37 0.64 11.59 0.53 2.03e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs4474465 0.646 rs7936011 chr11:78275931 G/T cg02023728 chr11:77925099 USP35 -0.34 -6.0 -0.31 5.01e-9 Alzheimer's disease (survival time); LIHC cis rs797680 0.856 rs797672 chr1:93702119 A/T cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.89 0.3 9.29e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs2836950 0.805 rs2836961 chr21:40627020 A/C cg11890956 chr21:40555474 PSMG1 -0.41 -6.16 -0.32 2.07e-9 Menarche (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg15034757 chr3:186617939 NA 0.47 6.05 0.31 3.83e-9 Hepatitis; LIHC cis rs34172651 0.517 rs34172679 chr16:24840381 C/T cg04756594 chr16:24857601 SLC5A11 0.61 8.66 0.42 1.94e-16 Intelligence (multi-trait analysis); LIHC cis rs6976053 0.518 rs144173 chr7:100416250 A/G cg01903971 chr7:100434983 NA -0.39 -6.18 -0.32 1.79e-9 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC trans rs4824093 0.610 rs73441745 chr22:50237606 G/A cg09872104 chr7:134855509 C7orf49 -0.77 -6.24 -0.32 1.33e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs7552404 0.924 rs114752222 chr1:76180878 C/T cg03433033 chr1:76189801 ACADM 0.69 10.53 0.49 1.18e-22 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10791323 0.575 rs4489760 chr11:133732265 A/T cg15485101 chr11:133734466 NA 0.26 6.22 0.32 1.45e-9 Childhood ear infection; LIHC cis rs748404 0.660 rs2249952 chr15:43720533 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.15 0.36 5.42e-12 Lung cancer; LIHC cis rs2842992 1.000 rs2758322 chr6:160075188 G/T cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.41 0.53 9.2e-26 Age-related macular degeneration (geographic atrophy); LIHC cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 -0.88 -8.51 -0.42 5.51e-16 Platelet count; LIHC cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg27286337 chr10:134555280 INPP5A 0.95 13.47 0.59 1.73e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1005277 0.579 rs1780122 chr10:38529509 C/A cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.81 -0.3 1.42e-8 Extrinsic epigenetic age acceleration; LIHC cis rs7903847 0.642 rs10882926 chr10:99160690 C/T cg06359132 chr10:99160096 RRP12 0.38 5.87 0.3 1.05e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs7224685 0.859 rs34348519 chr17:4094140 G/C cg11204139 chr17:3907470 NA 0.59 7.95 0.39 2.83e-14 Type 2 diabetes; LIHC cis rs1728785 1.000 rs1364109 chr16:68595505 T/C cg02972257 chr16:68554789 NA -0.55 -6.21 -0.32 1.55e-9 Ulcerative colitis; LIHC cis rs7954584 0.520 rs1169096 chr12:122465836 G/C cg13699009 chr12:122356056 WDR66 -0.4 -6.75 -0.34 6.42e-11 Mean corpuscular volume; LIHC cis rs6502050 0.805 rs4356529 chr17:80157797 A/G cg11859384 chr17:80120422 CCDC57 0.43 5.81 0.3 1.43e-8 Life satisfaction; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11166741 chr7:42951557 C7orf25 -0.43 -6.16 -0.32 2.03e-9 Bilirubin levels; LIHC cis rs17106184 0.583 rs57793888 chr1:51201424 A/G cg07174182 chr1:51127561 FAF1 -0.63 -6.86 -0.35 3.32e-11 Type 2 diabetes; LIHC cis rs2204008 0.837 rs4312131 chr12:38181087 G/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14331148 chr19:47551893 TMEM160 0.52 6.74 0.34 6.76e-11 Lung function (FEV1/FVC); LIHC cis rs2952156 0.920 rs1018246 chr17:37835240 C/T cg00129232 chr17:37814104 STARD3 -0.53 -10.19 -0.48 1.76e-21 Asthma; LIHC cis rs7116495 1.000 rs10751189 chr11:71670578 C/G cg26138937 chr11:71823887 C11orf51 0.7 7.22 0.36 3.42e-12 Severe influenza A (H1N1) infection; LIHC cis rs2153535 0.580 rs9328484 chr6:8524843 A/T cg07606381 chr6:8435919 SLC35B3 0.79 11.59 0.53 1.97e-26 Motion sickness; LIHC cis rs1552244 0.882 rs67895180 chr3:10026079 T/C cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs17152411 1.000 rs7082846 chr10:126593310 C/A cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg18252515 chr7:66147081 NA -1.28 -17.05 -0.68 1.28e-47 Diabetic kidney disease; LIHC cis rs739401 0.527 rs418832 chr11:3072236 C/T cg08508325 chr11:3079039 CARS -0.35 -7.56 -0.38 3.66e-13 Longevity; LIHC cis rs10216189 0.785 rs4352753 chr7:5527223 A/C cg05318486 chr7:5553423 FBXL18 -0.44 -6.17 -0.32 1.93e-9 Relative hand skill in reading disability; LIHC cis rs1577917 0.958 rs1838955 chr6:86565449 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC cis rs9611565 0.649 rs738422 chr22:42123399 C/T cg06634786 chr22:41940651 POLR3H 0.57 6.26 0.32 1.12e-9 Vitiligo; LIHC cis rs9818758 0.607 rs9990153 chr3:49291883 C/T cg06212747 chr3:49208901 KLHDC8B -0.65 -6.09 -0.31 3.07e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs17152411 0.895 rs11245418 chr10:126586319 T/C cg07906193 chr10:126599966 NA 0.44 6.89 0.35 2.74e-11 Height; LIHC cis rs1355223 0.583 rs2956076 chr11:34874124 T/C cg24088639 chr11:34937564 PDHX;APIP -0.39 -5.99 -0.31 5.17e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11098499 0.863 rs13134665 chr4:120426430 T/C cg09307838 chr4:120376055 NA 0.76 11.66 0.53 1.1e-26 Corneal astigmatism; LIHC cis rs17253792 0.822 rs79398217 chr14:56067350 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg13866156 chr1:1669148 SLC35E2 -0.67 -12.75 -0.57 9.86e-31 Body mass index; LIHC cis rs7707921 1.000 rs7707921 chr5:81538046 T/A cg15871215 chr5:81402204 ATG10 0.61 5.79 0.3 1.56e-8 Breast cancer; LIHC cis rs12824058 0.831 rs4759452 chr12:130812799 G/A cg24229701 chr12:130821962 PIWIL1 0.44 6.81 0.35 4.49e-11 Menopause (age at onset); LIHC cis rs36051895 0.664 rs17425637 chr9:5110000 C/T cg02405213 chr9:5042618 JAK2 -0.63 -10.67 -0.5 3.88e-23 Pediatric autoimmune diseases; LIHC cis rs965469 1.000 rs6051810 chr20:3355384 A/G cg25506879 chr20:3388711 C20orf194 -0.55 -6.6 -0.34 1.57e-10 IFN-related cytopenia; LIHC cis rs1577917 1.000 rs7766645 chr6:86622238 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.81 -0.39 7.29e-14 Response to antipsychotic treatment; LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg11494091 chr17:61959527 GH2 0.45 8.41 0.41 1.09e-15 Prudent dietary pattern; LIHC cis rs7659604 0.540 rs28394772 chr4:122678543 C/T cg19671926 chr4:122722719 EXOSC9 0.47 7.0 0.35 1.39e-11 Type 2 diabetes; LIHC cis rs11166927 0.524 rs2035088 chr8:140831403 A/G cg16909799 chr8:140841666 TRAPPC9 -0.49 -7.95 -0.4 2.68e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs2236918 0.643 rs1776139 chr1:242027363 T/G cg21919602 chr1:242011447 EXO1 -0.36 -5.74 -0.3 2.09e-8 Menopause (age at onset); LIHC cis rs34172651 0.517 rs11647120 chr16:24819806 A/G cg04756594 chr16:24857601 SLC5A11 0.6 8.78 0.43 8.09e-17 Intelligence (multi-trait analysis); LIHC cis rs16854884 0.657 rs35877644 chr3:143701755 A/G cg06585982 chr3:143692056 C3orf58 0.63 8.78 0.43 8.13e-17 Economic and political preferences (feminism/equality); LIHC cis rs72627509 0.638 rs12648928 chr4:57902506 C/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.55 -7.31 -0.37 1.88e-12 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs3106136 0.901 rs17623135 chr4:95213091 C/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.9 -0.39 3.77e-14 Capecitabine sensitivity; LIHC trans rs10838798 0.504 rs7479393 chr11:48295303 G/C cg15704280 chr7:45808275 SEPT13 -0.42 -6.37 -0.33 6.13e-10 Height; LIHC cis rs3823572 0.542 rs2346269 chr7:133643066 C/T cg03336402 chr7:133662267 EXOC4 -0.47 -5.81 -0.3 1.4e-8 Intelligence (multi-trait analysis); LIHC trans rs783540 0.934 rs783532 chr15:83249367 C/T cg18393722 chr15:85113863 UBE2QP1 -0.39 -6.79 -0.34 4.83e-11 Schizophrenia; LIHC cis rs35110281 0.591 rs86139 chr21:44932802 G/A cg21573476 chr21:45109991 RRP1B -0.48 -8.79 -0.43 7.41e-17 Mean corpuscular volume; LIHC cis rs2836974 0.563 rs6517522 chr21:40553845 T/C cg11890956 chr21:40555474 PSMG1 0.67 10.34 0.49 5.4e-22 Cognitive function; LIHC cis rs2952156 0.920 rs12940986 chr17:37836581 A/G cg00129232 chr17:37814104 STARD3 0.54 10.34 0.49 5.67e-22 Asthma; LIHC cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg21724239 chr8:58056113 NA 0.45 6.0 0.31 5.15e-9 Developmental language disorder (linguistic errors); LIHC cis rs4862750 0.914 rs1991255 chr4:187875340 G/A cg10295955 chr4:187884368 NA -0.95 -20.93 -0.75 3.29e-63 Lobe attachment (rater-scored or self-reported); LIHC cis rs644799 0.965 rs687529 chr11:95545587 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.14 0.68 5.42e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7647973 1.000 rs2140270 chr3:49439440 A/G cg07636037 chr3:49044803 WDR6 -0.53 -6.44 -0.33 4.07e-10 Menarche (age at onset); LIHC cis rs7086627 0.515 rs10887895 chr10:82210011 A/G cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg02018176 chr4:1364513 KIAA1530 0.43 5.85 0.3 1.15e-8 Longevity; LIHC cis rs796364 0.951 rs769952 chr2:200734368 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.09 0.44 8.32e-18 Schizophrenia; LIHC cis rs7487075 0.558 rs12580460 chr12:46648983 G/A cg15584813 chr12:47219626 SLC38A4 0.32 5.93 0.31 7.37e-9 Itch intensity from mosquito bite; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13663170 chr4:1976361 WHSC1;SCARNA22 0.49 6.19 0.32 1.71e-9 Systolic blood pressure; LIHC cis rs6089829 0.962 rs6011544 chr20:61658782 T/C cg03213289 chr20:61660250 NA 0.5 8.98 0.44 1.86e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs67478160 0.643 rs1535098 chr14:104216513 T/A cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.57 -0.38 3.54e-13 Schizophrenia; LIHC cis rs80282103 0.618 rs2387299 chr10:1163427 A/G cg08668510 chr10:1095578 IDI1 0.63 6.11 0.31 2.79e-9 Glomerular filtration rate (creatinine); LIHC cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs72843506 0.656 rs28622601 chr17:19958654 G/C cg12065943 chr17:19881925 AKAP10 -0.33 -6.01 -0.31 4.71e-9 Schizophrenia; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs67981189 0.593 rs10132984 chr14:71477227 A/T cg15816911 chr14:71606274 NA 0.4 6.38 0.33 5.79e-10 Schizophrenia; LIHC cis rs11758351 0.925 rs78932312 chr6:26194869 A/G cg03854865 chr6:26224070 HIST1H3E 0.63 7.07 0.36 8.82e-12 Gout;Renal underexcretion gout; LIHC cis rs3768617 0.510 rs6424884 chr1:183065904 C/T ch.1.3577855R chr1:183094577 LAMC1 0.63 10.92 0.51 5.31e-24 Fuchs's corneal dystrophy; LIHC cis rs7208859 0.524 rs77498725 chr17:29063986 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs74233809 1.000 rs12219027 chr10:104811203 T/C cg03493300 chr10:104813866 CNNM2 0.48 6.36 0.33 6.41e-10 Birth weight; LIHC cis rs12594515 1.000 rs8032361 chr15:45988553 T/C cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.8e-12 Waist circumference;Weight; LIHC cis rs796364 0.664 rs3106089 chr2:200884615 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.79 8.75 0.43 9.57e-17 Schizophrenia; LIHC cis rs10193935 0.901 rs222463 chr2:42644080 A/G cg27598129 chr2:42591480 NA -0.71 -10.15 -0.48 2.5e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs9303401 0.614 rs34550282 chr17:57092788 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.41 0.56 1.91e-29 Cognitive test performance; LIHC cis rs1153858 0.945 rs1974981 chr15:45729123 C/T cg26924012 chr15:45694286 SPATA5L1 -0.73 -13.02 -0.58 9.31e-32 Homoarginine levels; LIHC cis rs11098499 0.604 rs2389886 chr4:120570422 C/T cg09307838 chr4:120376055 NA 0.65 9.57 0.46 2.17e-19 Corneal astigmatism; LIHC cis rs16828019 0.777 rs115916606 chr1:41642700 C/G cg03387723 chr1:41708464 SCMH1 -0.44 -7.13 -0.36 6.14e-12 Intelligence (multi-trait analysis); LIHC trans rs3960554 0.674 rs113848658 chr7:75791858 G/A cg19862616 chr7:65841803 NCRNA00174 0.6 8.24 0.41 3.81e-15 Eotaxin levels; LIHC cis rs11098499 0.954 rs1022145 chr4:120230979 A/G cg09307838 chr4:120376055 NA 0.74 11.18 0.52 5.92e-25 Corneal astigmatism; LIHC cis rs904251 0.797 rs1757177 chr6:37486370 C/T cg08126542 chr6:37504118 NA -0.41 -6.6 -0.34 1.53e-10 Cognitive performance; LIHC cis rs1552244 0.882 rs13063098 chr3:10009919 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.63 -9.23 -0.45 2.97e-18 Alzheimer's disease; LIHC cis rs9457247 0.602 rs12208359 chr6:167458455 G/A cg23791538 chr6:167370224 RNASET2 -0.5 -7.36 -0.37 1.34e-12 Crohn's disease; LIHC cis rs986417 1.000 rs10136642 chr14:60946098 G/C cg27398547 chr14:60952738 C14orf39 0.81 9.39 0.45 8.69e-19 Gut microbiota (bacterial taxa); LIHC cis rs7927771 0.896 rs12794570 chr11:47658314 C/T cg20135002 chr11:47629003 NA -0.58 -10.13 -0.48 2.9e-21 Subjective well-being; LIHC cis rs344364 0.511 rs2982453 chr16:1949520 G/A cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs17401966 0.838 rs12139981 chr1:10390696 T/C cg15208524 chr1:10270712 KIF1B 0.38 5.74 0.3 2.1e-8 Hepatocellular carcinoma; LIHC cis rs8084351 0.599 rs4614799 chr18:50694304 A/G cg24270629 chr18:50823537 DCC 0.45 6.74 0.34 6.67e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs12594515 1.000 rs56220882 chr15:45997075 C/G cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC trans rs1814175 0.817 rs28525029 chr11:50045815 A/G cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs798554 0.757 rs1182198 chr7:2862906 C/T cg13628971 chr7:2884303 GNA12 0.57 7.88 0.39 4.28e-14 Height; LIHC cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 10.0 0.48 8.11e-21 Platelet count; LIHC cis rs11734570 0.581 rs73811714 chr4:38588327 T/G cg18361445 chr4:38666374 KLF3;FLJ13197 0.52 6.84 0.35 3.76e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4803468 1.000 rs6508977 chr19:41909346 A/G cg14132834 chr19:41945861 ATP5SL -0.44 -6.48 -0.33 3.26e-10 Height; LIHC cis rs10504073 0.584 rs11778863 chr8:49954893 C/T cg00325661 chr8:49890786 NA 0.34 7.65 0.38 2.03e-13 Blood metabolite ratios; LIHC cis rs7762018 0.607 rs78941587 chr6:170061157 G/C cg19338460 chr6:170058176 WDR27 -0.89 -9.64 -0.46 1.26e-19 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg21724239 chr8:58056113 NA 0.49 5.86 0.3 1.09e-8 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg02290350 chr8:58132656 NA 0.45 8.65 0.42 2.09e-16 Developmental language disorder (linguistic errors); LIHC cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.17 -0.44 4.52e-18 Bipolar disorder; LIHC cis rs12477438 0.520 rs2516830 chr2:99773702 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs7208859 0.623 rs11658945 chr17:29122509 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2439831 0.717 rs2447198 chr15:43895118 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.74 10.43 0.49 2.59e-22 Lung cancer in ever smokers; LIHC cis rs5769765 1.000 rs2092982 chr22:50282204 C/A cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.2 0.45 3.71e-18 Schizophrenia; LIHC cis rs7903847 0.596 rs10786340 chr10:99156563 G/C cg20016023 chr10:99160130 RRP12 -0.43 -6.69 -0.34 8.95e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs701145 0.556 rs355762 chr3:154012614 G/A cg16511985 chr3:153974050 SGEF 0.41 8.73 0.43 1.16e-16 Coronary artery disease; LIHC cis rs9303401 0.659 rs62083436 chr17:57031742 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.34 0.55 3.55e-29 Cognitive test performance; LIHC cis rs7208859 0.623 rs9898084 chr17:29082334 C/G cg13385521 chr17:29058706 SUZ12P 0.85 8.46 0.42 7.87e-16 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19858173 chr2:128099688 MAP3K2 -0.27 -6.38 -0.33 5.81e-10 Calcium levels; LIHC cis rs651907 0.535 rs34648996 chr3:101511202 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.07 0.51 1.47e-24 Colorectal cancer; LIHC cis rs6120849 0.586 rs2025096 chr20:33540000 G/A cg07148914 chr20:33460835 GGT7 0.51 5.75 0.3 1.94e-8 Protein C levels; LIHC cis rs10838687 0.736 rs1449626 chr11:47290759 A/C cg26139080 chr11:47293733 MADD -0.42 -5.84 -0.3 1.23e-8 Proinsulin levels; LIHC cis rs2797160 1.000 rs2797158 chr6:126009398 G/A cg05901451 chr6:126070800 HEY2 0.45 7.44 0.37 8.16e-13 Endometrial cancer; LIHC cis rs7927592 0.956 rs11228251 chr11:68244558 G/T cg01657329 chr11:68192670 LRP5 -0.45 -6.01 -0.31 4.71e-9 Total body bone mineral density; LIHC cis rs4917833 0.789 rs3179357 chr10:100218732 C/T cg19043522 chr10:100227446 HPSE2 -0.41 -5.87 -0.3 1.01e-8 Pediatric bone mineral density (femoral neck); LIHC cis rs11122272 0.735 rs2739509 chr1:231526765 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.62 -0.5 5.69e-23 Hemoglobin concentration; LIHC cis rs8017423 0.935 rs17188598 chr14:90722473 A/T cg14092571 chr14:90743983 NA -0.38 -6.12 -0.31 2.58e-9 Mortality in heart failure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25163015 chr11:64052221 BAD;GPR137 0.45 6.22 0.32 1.44e-9 Lung function (FEV1/FVC); LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg03874509 chr1:107600012 PRMT6 0.74 11.64 0.53 1.36e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2236918 0.622 rs1776177 chr1:242012149 C/T cg21919602 chr1:242011447 EXO1 -0.37 -5.76 -0.3 1.86e-8 Menopause (age at onset); LIHC cis rs875971 0.545 rs3735147 chr7:65970528 A/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 7.02 0.35 1.21e-11 Aortic root size; LIHC cis rs4555082 1.000 rs7146683 chr14:105759385 A/G cg13114125 chr14:105738426 BRF1 -0.69 -9.34 -0.45 1.3e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs7582720 1.000 rs72926802 chr2:203830228 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs735396 1.000 rs1169313 chr12:121442670 C/T cg02403541 chr12:121454288 C12orf43 -0.45 -8.11 -0.4 8.87e-15 N-glycan levels; LIHC trans rs911555 0.574 rs34251103 chr14:103860063 A/G cg17675199 chr6:35436792 RPL10A -0.4 -8.18 -0.4 5.57e-15 Intelligence (multi-trait analysis); LIHC cis rs55702914 0.742 rs6744206 chr2:198148522 A/G cg03934865 chr2:198174659 NA -0.4 -5.8 -0.3 1.52e-8 Major depression and alcohol dependence; LIHC cis rs6430585 0.527 rs12465544 chr2:136451676 C/T cg07169764 chr2:136633963 MCM6 0.67 8.55 0.42 4.1e-16 Corneal structure; LIHC trans rs11148252 0.574 rs9536247 chr13:53279542 T/C cg18335740 chr13:41363409 SLC25A15 0.55 10.04 0.48 5.92e-21 Lewy body disease; LIHC cis rs2839186 0.656 rs8128380 chr21:47665693 C/T cg09417038 chr21:47716443 C21orf57 -0.51 -7.4 -0.37 1.05e-12 Testicular germ cell tumor; LIHC cis rs4453791 1.000 rs35674337 chr3:38878881 G/A cg02254461 chr3:39195904 CSRNP1 0.64 5.76 0.3 1.86e-8 Social communication problems; LIHC cis rs4563143 0.514 rs112540771 chr19:29316100 C/T cg14983838 chr19:29218262 NA 0.41 6.04 0.31 4.01e-9 Methadone dose in opioid dependence; LIHC cis rs1461503 0.966 rs11218907 chr11:122841562 A/G cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs929354 0.651 rs6951298 chr7:156949149 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs7208859 0.524 rs60114476 chr17:29097667 A/T cg14067834 chr17:29058358 SUZ12P 0.7 7.0 0.35 1.32e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4638749 0.677 rs13022268 chr2:108837320 A/G cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs10464366 0.544 rs953874 chr7:39147916 G/A cg18850127 chr7:39170497 POU6F2 0.45 8.0 0.4 1.9e-14 IgG glycosylation; LIHC cis rs12586317 0.547 rs12435454 chr14:35466997 A/G cg16230307 chr14:35515116 FAM177A1 0.79 13.3 0.58 8.3e-33 Psoriasis; LIHC trans rs4650994 1.000 rs4354501 chr1:178524596 T/C cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs243505 0.691 rs243483 chr7:148449163 A/G cg09806900 chr7:148480153 CUL1 -0.42 -5.98 -0.31 5.57e-9 Inflammatory bowel disease;Crohn's disease; LIHC trans rs3960554 0.808 rs79864016 chr7:75655838 A/G cg19862616 chr7:65841803 NCRNA00174 0.59 8.17 0.4 6.2e-15 Eotaxin levels; LIHC cis rs249954 0.512 rs7588 chr16:23681165 G/A cg09867953 chr16:23706666 ERN2 0.36 6.09 0.31 3.07e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.45 7.48 0.37 6.49e-13 Height; LIHC cis rs4820294 0.926 rs62236671 chr22:38069305 G/A cg10587741 chr22:38071170 LGALS1 0.73 12.69 0.57 1.7e-30 Fat distribution (HIV); LIHC trans rs11722228 0.522 rs12503195 chr4:10082772 T/C cg26043149 chr18:55253948 FECH 0.41 6.32 0.32 7.95e-10 Gout;Urate levels;Serum uric acid levels; LIHC cis rs67460515 0.563 rs35914913 chr3:160826561 A/G cg03342759 chr3:160939853 NMD3 -0.61 -8.96 -0.44 2.11e-17 Parkinson's disease; LIHC cis rs4727027 0.899 rs7791496 chr7:148863674 C/G cg23583168 chr7:148888333 NA -0.73 -10.28 -0.49 9.12e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs916888 0.773 rs199451 chr17:44801784 G/A cg13957321 chr17:43675089 NA 0.5 8.0 0.4 2.01e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7584330 0.554 rs6760913 chr2:238400702 C/T cg08992911 chr2:238395768 MLPH 0.64 6.47 0.33 3.36e-10 Prostate cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05464172 chr8:97247954 UQCRB 0.45 6.55 0.33 2.07e-10 Pancreatic cancer; LIHC cis rs6582630 0.598 rs11182207 chr12:38477514 T/C cg26384229 chr12:38710491 ALG10B -0.43 -5.92 -0.3 7.79e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs72843506 0.586 rs79246843 chr17:19842062 G/A cg12065943 chr17:19881925 AKAP10 -0.39 -6.57 -0.33 1.93e-10 Schizophrenia; LIHC cis rs1580019 0.587 rs6972365 chr7:32548931 T/A cg06627557 chr7:32535165 LSM5;AVL9 1.13 25.87 0.81 1.63e-82 Cognitive ability; LIHC cis rs9291683 0.588 rs12647117 chr4:10022059 T/C cg11266682 chr4:10021025 SLC2A9 0.34 7.31 0.37 1.89e-12 Bone mineral density; LIHC cis rs9911578 0.874 rs302865 chr17:56756977 A/G cg05425664 chr17:57184151 TRIM37 -0.56 -8.33 -0.41 2.03e-15 Intelligence (multi-trait analysis); LIHC cis rs6665290 0.935 rs17600669 chr1:227201871 A/G cg10327440 chr1:227177885 CDC42BPA -1.16 -28.66 -0.84 6.08e-93 Myeloid white cell count; LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs9393777 0.513 rs11967852 chr6:26612870 G/T cg12826209 chr6:26865740 GUSBL1 0.56 5.74 0.3 2.05e-8 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg11817910 chr12:31944836 H3F3C 0.47 6.43 0.33 4.35e-10 Hepatitis; LIHC cis rs6089584 1.000 rs6089587 chr20:60564829 C/T cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs57590327 0.555 rs3943556 chr3:81738892 G/C cg07356753 chr3:81810745 GBE1 -0.55 -8.38 -0.41 1.39e-15 Extraversion; LIHC cis rs2012796 0.704 rs57670850 chr14:81841577 C/T cg23690444 chr14:81902736 NA -0.5 -6.89 -0.35 2.76e-11 Night sleep phenotypes; LIHC cis rs12101261 1.000 rs2160215 chr14:81461472 T/C cg06600135 chr14:81408086 NA 0.37 6.33 0.32 7.5e-10 Graves' disease; LIHC cis rs34779708 0.931 rs11010130 chr10:35513307 T/C cg03585969 chr10:35415529 CREM 0.86 12.65 0.56 2.29e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs922107 0.764 rs4658279 chr1:90022799 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.73 -0.39 1.21e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs679087 1.000 rs439639 chr12:29917641 A/C cg14258853 chr12:29935411 TMTC1 -0.5 -7.82 -0.39 6.65e-14 Schizophrenia; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg14004847 chr7:1930337 MAD1L1 -0.41 -5.77 -0.3 1.82e-8 Bipolar disorder and schizophrenia; LIHC trans rs637571 0.726 rs526631 chr11:65681965 T/G cg17712092 chr4:129076599 LARP1B -0.76 -11.98 -0.54 7.22e-28 Eosinophil percentage of white cells; LIHC cis rs11577318 0.853 rs3795684 chr1:26632781 C/T cg00852783 chr1:26633632 UBXN11 0.41 6.5 0.33 2.85e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11112613 0.653 rs941101 chr12:105937098 T/G cg03607813 chr12:105948248 NA 0.62 11.05 0.51 1.76e-24 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs1000083 0.748 rs1830368 chr5:96634367 T/C ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg07424592 chr7:64974309 NA -0.8 -9.32 -0.45 1.44e-18 Diabetic kidney disease; LIHC cis rs7618501 1.000 rs3749241 chr3:49744392 A/G cg24110177 chr3:50126178 RBM5 0.42 6.46 0.33 3.55e-10 Intelligence (multi-trait analysis); LIHC cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg10862848 chr6:42927986 GNMT -0.26 -6.3 -0.32 9.18e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7100689 0.697 rs4934084 chr10:82116960 T/C cg00277334 chr10:82204260 NA -0.54 -6.68 -0.34 9.51e-11 Post bronchodilator FEV1; LIHC trans rs2243480 0.708 rs35825036 chr7:65986502 T/C cg07424592 chr7:64974309 NA 0.78 8.94 0.44 2.44e-17 Diabetic kidney disease; LIHC cis rs10540 0.749 rs61877777 chr11:526356 G/A cg03352830 chr11:487213 PTDSS2 0.79 6.38 0.33 5.73e-10 Body mass index; LIHC cis rs56104184 0.830 rs73061622 chr19:49358111 C/T cg15549821 chr19:49342101 PLEKHA4 -1.15 -9.46 -0.46 4.94e-19 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7872515 0.775 rs1970121 chr9:94870152 A/C cg01248375 chr9:94877805 SPTLC1 -0.53 -8.04 -0.4 1.51e-14 Bipolar disorder and schizophrenia; LIHC cis rs7772486 0.806 rs7740785 chr6:146171299 C/A cg05347473 chr6:146136440 FBXO30 0.36 6.08 0.31 3.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9583531 0.527 rs2391866 chr13:111363294 A/T cg15841412 chr13:111365552 ING1 0.47 5.87 0.3 1.03e-8 Coronary artery disease; LIHC cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.09 0.44 8.2e-18 Bipolar disorder; LIHC cis rs34172651 0.517 rs200526 chr16:24760511 C/T cg04756594 chr16:24857601 SLC5A11 -0.59 -8.93 -0.43 2.73e-17 Intelligence (multi-trait analysis); LIHC cis rs7582720 1.000 rs72932780 chr2:203695826 G/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1707322 1.000 rs4460583 chr1:46449918 C/G cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6502050 0.805 rs4789740 chr17:80119202 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs2842992 0.830 rs1998365 chr6:160179535 A/T cg11366901 chr6:160182831 ACAT2 0.94 15.54 0.64 1.36e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs4253772 0.637 rs9627350 chr22:46663017 A/G cg24881330 chr22:46731750 TRMU 0.55 5.83 0.3 1.3e-8 LDL cholesterol;Cholesterol, total; LIHC cis rs2952156 0.684 rs1877031 chr17:37814080 G/A cg07936489 chr17:37558343 FBXL20 -0.43 -6.49 -0.33 3.1e-10 Asthma; LIHC cis rs9682041 0.696 rs9872796 chr3:170099393 T/G cg11886554 chr3:170076028 SKIL 0.74 6.31 0.32 8.57e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs10751667 0.666 rs10902239 chr11:946484 A/G ch.11.42038R chr11:967971 AP2A2 -0.55 -9.93 -0.47 1.39e-20 Alzheimer's disease (late onset); LIHC cis rs854572 0.600 rs705382 chr7:94955221 C/G cg17330251 chr7:94953956 PON1 -0.54 -9.22 -0.45 3.15e-18 Paraoxonase activity; LIHC cis rs9457247 0.765 rs6904946 chr6:167433948 C/T cg12798992 chr6:167411361 FGFR1OP -0.49 -7.59 -0.38 3.01e-13 Crohn's disease; LIHC cis rs477895 0.838 rs11607007 chr11:64007976 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 9.23 0.45 2.89e-18 Mean platelet volume; LIHC cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg10935138 chr17:73851978 WBP2 0.81 7.31 0.37 1.88e-12 Psoriasis; LIHC cis rs4819852 1.000 rs1034565 chr22:19984211 A/G cg07821417 chr22:19972146 ARVCF -0.42 -5.76 -0.3 1.84e-8 Pulse pressure; LIHC cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg18278486 chr6:26987575 LOC100270746;C6orf41 0.29 5.84 0.3 1.21e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg00612595 chr21:47717864 NA -0.35 -5.76 -0.3 1.85e-8 Testicular germ cell tumor; LIHC cis rs4819052 0.851 rs35064782 chr21:46674360 G/A cg22633049 chr21:46681294 NA -0.36 -6.24 -0.32 1.27e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7772486 0.701 rs697056 chr6:146003897 C/T cg23711669 chr6:146136114 FBXO30 -0.73 -13.1 -0.58 4.62e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs1008375 0.932 rs12500947 chr4:17603424 C/T cg02297831 chr4:17616191 MED28 0.4 5.78 0.3 1.65e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1005277 0.579 rs2008449 chr10:38414204 A/T cg00409905 chr10:38381863 ZNF37A 0.59 10.31 0.49 6.75e-22 Extrinsic epigenetic age acceleration; LIHC cis rs9303401 0.614 rs34678056 chr17:57177549 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.84 0.54 2.44e-27 Cognitive test performance; LIHC cis rs3749237 0.595 rs1568661 chr3:49520958 A/G cg03060546 chr3:49711283 APEH 0.6 9.83 0.47 3.03e-20 Resting heart rate; LIHC cis rs7659604 0.521 rs4240263 chr4:122683623 C/T cg19671926 chr4:122722719 EXOSC9 0.53 8.16 0.4 6.41e-15 Type 2 diabetes; LIHC cis rs950169 0.881 rs62029596 chr15:84955434 A/G cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.12e-11 Schizophrenia; LIHC cis rs1552244 0.572 rs6442154 chr3:10168785 A/G cg00149659 chr3:10157352 C3orf10 0.92 8.97 0.44 1.95e-17 Alzheimer's disease; LIHC cis rs4654899 0.758 rs6693055 chr1:21421813 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.75 0.3 1.98e-8 Superior frontal gyrus grey matter volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03530756 chr16:3285262 ZNF200 0.46 6.42 0.33 4.68e-10 Lung function (FEV1/FVC); LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.24 0.55 7.84e-29 Prudent dietary pattern; LIHC cis rs9486715 1.000 rs7752277 chr6:97065131 C/T cg18709589 chr6:96969512 KIAA0776 -0.36 -6.28 -0.32 1.02e-9 Headache; LIHC cis rs9394841 0.692 rs3806113 chr6:41876335 C/T cg17623882 chr6:41773611 USP49 -0.45 -6.85 -0.35 3.35e-11 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs8044868 0.512 rs4788461 chr16:72156000 C/A cg16558253 chr16:72132732 DHX38 -0.38 -6.43 -0.33 4.3e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs2997447 0.739 rs3008223 chr1:26389633 T/C cg19633962 chr1:26362018 EXTL1 -0.53 -5.99 -0.31 5.23e-9 QRS complex (12-leadsum); LIHC cis rs61990749 0.597 rs1006039 chr14:78263196 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.65 -9.98 -0.47 9.4499999999999992e-21 Fibroblast growth factor basic levels; LIHC cis rs870825 0.860 rs34985821 chr4:185599489 G/A cg04058563 chr4:185651563 MLF1IP 0.84 7.01 0.35 1.31e-11 Blood protein levels; LIHC cis rs2933343 0.700 rs789233 chr3:128603150 G/T cg25356066 chr3:128598488 ACAD9 0.55 7.67 0.38 1.85e-13 IgG glycosylation; LIHC cis rs72634258 0.945 rs12748993 chr1:8129507 A/G cg00042356 chr1:8021962 PARK7 0.73 7.45 0.37 7.71e-13 Inflammatory bowel disease; LIHC trans rs2243480 1.000 rs778679 chr7:65840911 A/G cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg26338869 chr17:61819248 STRADA 0.52 6.91 0.35 2.33e-11 Height; LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.11 -0.31 2.78e-9 Total body bone mineral density; LIHC cis rs17376456 0.877 rs10035340 chr5:93490465 C/T cg25358565 chr5:93447407 FAM172A 1.1 9.68 0.46 9.54e-20 Diabetic retinopathy; LIHC cis rs1003719 0.591 rs1053966 chr21:38568009 G/C cg10648535 chr21:38446584 PIGP;TTC3 -0.54 -6.61 -0.34 1.51e-10 Eye color traits; LIHC cis rs12971120 0.838 rs3794950 chr18:72182965 G/A cg26446133 chr18:72167187 CNDP2 -0.76 -13.02 -0.58 9.16e-32 Refractive error; LIHC trans rs11098499 0.954 rs71629403 chr4:120372567 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.81 0.47 3.5e-20 Corneal astigmatism; LIHC cis rs17001868 0.892 rs73167023 chr22:40799954 T/C cg07138101 chr22:40742427 ADSL 0.57 6.17 0.32 1.94e-9 Mammographic density (dense area); LIHC cis rs11971779 0.680 rs7801613 chr7:139039927 A/G cg07862535 chr7:139043722 LUC7L2 -0.59 -10.07 -0.48 4.73e-21 Diisocyanate-induced asthma; LIHC trans rs4332037 0.615 rs62435134 chr7:1895463 T/G cg11693508 chr17:37793320 STARD3 0.61 6.14 0.32 2.24e-9 Bipolar disorder; LIHC cis rs9368481 0.729 rs10946881 chr6:26914611 C/T cg12292205 chr6:26970375 C6orf41 0.45 7.55 0.38 4.11e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs614226 1.000 rs1614223 chr12:120964043 T/C cg27489772 chr12:121021490 NA 0.51 5.72 0.3 2.33e-8 Type 1 diabetes nephropathy; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24685795 chr17:34851276 ZNHIT3 0.53 6.99 0.35 1.41e-11 Systolic blood pressure; LIHC cis rs6088590 0.561 rs6059932 chr20:33175466 C/T cg08999081 chr20:33150536 PIGU 0.69 13.74 0.6 1.68e-34 Coronary artery disease; LIHC trans rs6489882 0.867 rs7132404 chr12:113368605 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs10791097 0.667 rs2155358 chr11:130740357 T/C cg22079354 chr11:130786696 SNX19 0.42 6.02 0.31 4.43e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg06873352 chr17:61820015 STRADA 0.72 12.72 0.57 1.29e-30 Prudent dietary pattern; LIHC cis rs9640161 0.750 rs4395803 chr7:150025367 A/C cg17279839 chr7:150038598 RARRES2 0.57 11.5 0.53 4.28e-26 Blood protein levels;Circulating chemerin levels; LIHC cis rs1451375 1.000 rs6949897 chr7:50621920 C/T cg14593290 chr7:50529359 DDC 0.42 6.89 0.35 2.67e-11 Malaria; LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.88 -0.3 9.68e-9 Total body bone mineral density; LIHC cis rs11229555 0.645 rs12786744 chr11:58177549 T/C cg15696309 chr11:58395628 NA -0.65 -7.65 -0.38 2.11e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7927771 0.690 rs35496532 chr11:47450338 C/T cg20307385 chr11:47447363 PSMC3 -0.48 -6.2 -0.32 1.67e-9 Subjective well-being; LIHC cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg05025164 chr4:1340916 KIAA1530 -0.4 -6.01 -0.31 4.78e-9 Obesity-related traits; LIHC cis rs7100689 0.646 rs1538823 chr10:82088040 C/A cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg26531700 chr6:26746687 NA 0.39 6.4 0.33 5.18e-10 Intelligence (multi-trait analysis); LIHC cis rs4925386 1.000 rs6089351 chr20:60916153 G/A cg24112000 chr20:60950667 NA 0.44 7.02 0.36 1.17e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC trans rs4843747 0.749 rs72818535 chr16:88074039 G/A cg09572067 chr16:29127029 RRN3P2 0.56 8.51 0.42 5.35e-16 Menopause (age at onset); LIHC cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg08125733 chr17:73851984 WBP2 0.96 9.09 0.44 7.98e-18 Psoriasis; LIHC cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.13 -17.49 -0.69 2.27e-49 Gut microbiome composition (summer); LIHC cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.81 10.6 0.5 6.89e-23 Alzheimer's disease; LIHC cis rs8177253 0.514 rs6790668 chr3:133442481 T/A cg24879335 chr3:133465180 TF 0.37 8.37 0.41 1.49e-15 Iron status biomarkers; LIHC cis rs7772486 0.875 rs2748490 chr6:146329681 G/T cg23711669 chr6:146136114 FBXO30 0.6 10.51 0.49 1.45e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg23205692 chr1:25664452 TMEM50A 0.39 6.43 0.33 4.39e-10 Erythrocyte sedimentation rate; LIHC cis rs4819052 0.851 rs7276591 chr21:46680156 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.59 0.38 3.09e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6840360 0.593 rs2089811 chr4:152685171 C/T cg22705602 chr4:152727874 NA 0.38 8.17 0.4 5.93e-15 Intelligence (multi-trait analysis); LIHC trans rs7615952 1.000 rs9289275 chr3:125648659 A/T cg07211511 chr3:129823064 LOC729375 -0.83 -10.33 -0.49 5.79e-22 Blood pressure (smoking interaction); LIHC cis rs644799 1.000 rs1944074 chr11:95511445 C/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.78 0.3 1.71e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7512552 0.839 rs1260386 chr1:150369622 G/T cg15654264 chr1:150340011 RPRD2 0.68 11.27 0.52 2.96e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs250677 0.958 rs17109282 chr5:148416677 A/G cg18129178 chr5:148520854 ABLIM3 0.48 6.61 0.34 1.48e-10 Breast cancer; LIHC cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs9291683 0.609 rs7678012 chr4:9993772 T/C cg11266682 chr4:10021025 SLC2A9 0.3 6.35 0.32 6.86e-10 Bone mineral density; LIHC cis rs9640161 0.789 rs2098053 chr7:150043205 G/A cg27494647 chr7:150038898 RARRES2 0.35 6.37 0.33 6.16e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs56116382 0.604 rs9858428 chr3:49877585 G/T cg00383909 chr3:49044727 WDR6 0.85 6.15 0.32 2.22e-9 Intelligence (multi-trait analysis);High light scatter reticulocyte count; LIHC cis rs7100689 0.646 rs10400045 chr10:82077032 A/G cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs10870270 1.000 rs4880246 chr10:133764064 C/T cg17892150 chr10:133769511 PPP2R2D -0.68 -12.82 -0.57 5.55e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs769267 0.965 rs2315025 chr19:19426609 C/T cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.24 0.32 1.31e-9 Tonsillectomy; LIHC cis rs11971779 0.838 rs11764161 chr7:139115198 T/C cg07862535 chr7:139043722 LUC7L2 0.63 10.44 0.49 2.51e-22 Diisocyanate-induced asthma; LIHC cis rs57920188 0.640 rs4478781 chr1:4086827 C/T cg20703997 chr1:4087676 NA 0.56 7.37 0.37 1.31e-12 Interleukin-17 levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05170863 chr8:109261119 EIF3E 0.43 6.35 0.32 6.74e-10 Cognitive function; LIHC cis rs6748734 1.000 rs11898716 chr2:241828311 A/G cg09990169 chr2:241835740 C2orf54 -0.66 -9.32 -0.45 1.47e-18 Urinary metabolites; LIHC cis rs6060717 0.610 rs2590965 chr20:34613120 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.48 8.06 0.4 1.3e-14 Hip circumference adjusted for BMI; LIHC cis rs11148252 0.553 rs7999849 chr13:53249414 A/G cg12458913 chr13:53173898 NA 0.48 7.9 0.39 3.83e-14 Lewy body disease; LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC trans rs783540 0.934 rs4779053 chr15:83371598 T/C cg18393722 chr15:85113863 UBE2QP1 0.38 6.67 0.34 1.03e-10 Schizophrenia; LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.680 rs7805824 chr7:139111169 C/G cg07862535 chr7:139043722 LUC7L2 -0.6 -10.31 -0.49 6.76e-22 Diisocyanate-induced asthma; LIHC cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg06453172 chr10:134556979 INPP5A -0.61 -8.07 -0.4 1.19e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9640161 0.742 rs11983355 chr7:150016697 A/C cg10018233 chr7:150070692 REPIN1 0.54 9.21 0.45 3.44e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs1707322 0.686 rs3014242 chr1:46087577 G/A cg06784218 chr1:46089804 CCDC17 -0.44 -8.22 -0.41 4.38e-15 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 0.666 rs13242072 chr7:65765988 A/G cg14393609 chr7:65229607 NA -0.39 -5.79 -0.3 1.61e-8 Aortic root size; LIHC trans rs79976124 0.879 rs77185357 chr6:66629070 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.73 0.34 7.17e-11 Type 2 diabetes; LIHC cis rs2303759 0.551 rs7249040 chr19:49790602 C/T cg22307029 chr19:49891270 CCDC155 0.54 8.35 0.41 1.67e-15 Multiple sclerosis; LIHC cis rs12477438 0.539 rs13394175 chr2:99590713 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.51 -7.0 -0.35 1.37e-11 Chronic sinus infection; LIHC cis rs876084 0.505 rs12546625 chr8:121155225 C/T cg06265175 chr8:121136014 COL14A1 0.39 6.09 0.31 3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg16606324 chr3:10149918 C3orf24 0.52 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC trans rs17685 0.697 rs28689051 chr7:75763624 G/A cg19862616 chr7:65841803 NCRNA00174 0.91 18.57 0.71 1.01e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7818688 0.697 rs11783985 chr8:95979886 A/G cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs990171 0.560 rs4851548 chr2:102767532 A/G cg22835712 chr2:102737379 NA 0.61 6.06 0.31 3.54e-9 Lymphocyte counts; LIHC cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.643 rs4674324 chr2:219523433 T/G cg02985541 chr2:219472218 PLCD4 0.43 7.91 0.39 3.66e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs7116495 0.867 rs604671 chr11:71555904 A/G cg26138937 chr11:71823887 C11orf51 0.64 5.95 0.31 6.58e-9 Severe influenza A (H1N1) infection; LIHC cis rs8067354 0.645 rs2102507 chr17:57875907 A/G cg02344993 chr17:57696989 CLTC 0.69 11.67 0.53 1.01e-26 Hemoglobin concentration; LIHC cis rs6502050 0.835 rs8078087 chr17:80113322 T/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs909341 0.537 rs11696871 chr20:62387417 C/T cg14758556 chr20:62440591 NA 0.42 6.75 0.34 6.51e-11 Atopic dermatitis; LIHC cis rs7100689 0.516 rs10788546 chr10:82034854 T/C cg01528321 chr10:82214614 TSPAN14 0.84 11.11 0.52 1.07e-24 Post bronchodilator FEV1; LIHC cis rs17253792 0.822 rs10148122 chr14:56146694 G/T cg01858014 chr14:56050164 KTN1 -0.7 -8.08 -0.4 1.12e-14 Putamen volume; LIHC cis rs4665809 1.000 rs6729757 chr2:26285102 A/G cg04944784 chr2:26401820 FAM59B -0.66 -8.22 -0.41 4.16e-15 Gut microbiome composition (summer); LIHC cis rs6500602 0.627 rs3848372 chr16:4587875 C/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.46 6.75 0.34 6.17e-11 Schizophrenia; LIHC cis rs2228479 0.850 rs12596934 chr16:89841605 T/G cg19635926 chr16:89946313 TCF25 0.5 6.48 0.33 3.24e-10 Skin colour saturation; LIHC cis rs2073300 0.609 rs6132609 chr20:23400412 A/C cg16736954 chr20:23401023 NAPB 0.71 8.5 0.42 5.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3008870 1.000 rs1925408 chr1:67365034 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.56 0.67 1.24e-45 Lymphocyte percentage of white cells; LIHC cis rs11233413 0.508 rs7947780 chr11:82643760 A/C cg24227371 chr11:82718527 RAB30 0.31 6.85 0.35 3.44e-11 Economic and political preferences (feminism/equality); LIHC cis rs2228479 0.850 rs17227263 chr16:89810598 G/A cg06558623 chr16:89946397 TCF25 0.87 11.95 0.54 9.72e-28 Skin colour saturation; LIHC cis rs6502050 0.835 rs34620191 chr17:80149532 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.78 -0.3 1.64e-8 Life satisfaction; LIHC cis rs6750795 0.777 rs10210351 chr2:232348665 A/G cg19187155 chr2:232395269 NMUR1 0.54 7.78 0.39 8.39e-14 Height; LIHC cis rs798554 0.567 rs1182194 chr7:2868824 C/G cg19717773 chr7:2847554 GNA12 -0.42 -7.23 -0.36 3.27e-12 Height; LIHC cis rs2635047 0.631 rs2668778 chr18:44745185 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.43 5.97 0.31 5.98e-9 Educational attainment; LIHC cis rs7918232 0.882 rs788211 chr10:27479070 C/T cg14442939 chr10:27389572 ANKRD26 -0.67 -6.54 -0.33 2.3e-10 Breast cancer; LIHC cis rs17286411 0.750 rs11075910 chr16:71936733 A/G cg06353428 chr16:71660113 MARVELD3 0.57 7.14 0.36 5.62e-12 Blood protein levels; LIHC cis rs870825 0.616 rs7678900 chr4:185635249 A/G cg04058563 chr4:185651563 MLF1IP 0.58 6.28 0.32 1.05e-9 Blood protein levels; LIHC cis rs6061231 0.798 rs2427308 chr20:60969451 C/T cg24112000 chr20:60950667 NA -0.61 -8.14 -0.4 7.23e-15 Colorectal cancer; LIHC cis rs11719291 0.833 rs11715835 chr3:48770732 C/T cg07636037 chr3:49044803 WDR6 -0.79 -8.23 -0.41 4.01e-15 Cognitive function; LIHC cis rs6430585 0.527 rs1900306 chr2:136416533 G/A cg07169764 chr2:136633963 MCM6 0.71 8.87 0.43 4.17e-17 Corneal structure; LIHC cis rs7843479 0.544 rs7839925 chr8:21792983 G/C cg17168535 chr8:21777572 XPO7 0.61 10.94 0.51 4.51e-24 Mean corpuscular volume; LIHC cis rs921968 0.565 rs6436086 chr2:219640125 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs4407350 0.806 rs5765706 chr22:44909045 A/G cg11695653 chr22:44894386 LDOC1L -0.36 -6.06 -0.31 3.69e-9 Intelligence (multi-trait analysis); LIHC cis rs701145 0.529 rs355746 chr3:153961627 C/G cg16511985 chr3:153974050 SGEF 0.42 9.11 0.44 7.14e-18 Coronary artery disease; LIHC cis rs57590327 0.503 rs13066091 chr3:81589912 T/C cg07356753 chr3:81810745 GBE1 -0.52 -7.95 -0.4 2.68e-14 Extraversion; LIHC cis rs17685 0.753 rs12531559 chr7:75631697 C/T cg04610667 chr7:75704037 NA 0.33 5.94 0.31 6.98e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10751667 0.621 rs10794351 chr11:946228 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.12 0.48 3.02e-21 Alzheimer's disease (late onset); LIHC cis rs7666738 0.830 rs3852122 chr4:98697400 T/C cg05340658 chr4:99064831 C4orf37 0.65 11.62 0.53 1.56e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs6732160 0.691 rs2007191 chr2:73421463 T/G cg24220031 chr2:73402428 NA -0.27 -5.9 -0.3 8.62e-9 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.721 rs4559551 chr1:46167533 T/C cg03146154 chr1:46216737 IPP 0.59 10.32 0.49 6.42e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7927592 0.956 rs2510384 chr11:68391837 C/A cg16797656 chr11:68205561 LRP5 0.49 7.65 0.38 2.11e-13 Total body bone mineral density; LIHC cis rs7408868 0.706 rs2238642 chr19:15282237 T/C cg02272795 chr19:15279244 NOTCH3 -0.31 -6.2 -0.32 1.61e-9 Pulse pressure; LIHC trans rs6692729 0.931 rs1296171 chr1:227059606 C/G cg24931520 chr6:99291587 NA 0.36 6.07 0.31 3.44e-9 Electrodermal activity; LIHC cis rs6424115 1.000 rs4237 chr1:24114129 C/T cg10978503 chr1:24200527 CNR2 0.32 7.41 0.37 9.76e-13 Immature fraction of reticulocytes; LIHC cis rs1005277 0.579 rs1780145 chr10:38537070 A/G cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.9 -0.3 8.56e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1823913 1.000 rs4853461 chr2:192119298 C/T cg12404831 chr2:192114017 MYO1B -0.33 -6.58 -0.34 1.75e-10 Obesity-related traits; LIHC cis rs7914558 0.966 rs943035 chr10:104839152 T/C cg15744005 chr10:104629667 AS3MT -0.37 -8.39 -0.41 1.29e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg14004847 chr7:1930337 MAD1L1 -0.42 -6.18 -0.32 1.87e-9 Bipolar disorder and schizophrenia; LIHC cis rs9942416 0.660 rs17649055 chr5:74984269 C/T cg19683494 chr5:74908142 NA 0.58 7.6 0.38 2.94e-13 Age-related disease endophenotypes; LIHC cis rs2749592 0.918 rs11011388 chr10:38155210 C/T cg00409905 chr10:38381863 ZNF37A 0.44 6.88 0.35 2.86e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9527 0.571 rs10786715 chr10:104620735 G/C cg15744005 chr10:104629667 AS3MT -0.46 -10.53 -0.49 1.2e-22 Arsenic metabolism; LIHC cis rs9790314 0.586 rs73021449 chr3:161128941 G/A cg03342759 chr3:160939853 NMD3 -0.55 -8.66 -0.42 1.86e-16 Morning vs. evening chronotype; LIHC cis rs1670533 1.000 rs28562028 chr4:1055115 G/A cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC cis rs896854 0.517 rs1011795 chr8:95951073 G/A cg13393036 chr8:95962371 TP53INP1 -0.37 -7.98 -0.4 2.19e-14 Type 2 diabetes; LIHC cis rs4700695 0.841 rs36301 chr5:65348940 A/G cg21114390 chr5:65439923 SFRS12 0.45 5.87 0.3 1.01e-8 Facial morphology (factor 19); LIHC trans rs13325613 0.915 rs1542755 chr3:46272440 A/C cg26337592 chr1:153642686 ILF2 -0.69 -6.48 -0.33 3.22e-10 Monocyte count; LIHC cis rs798554 0.797 rs798494 chr7:2798294 C/A cg13628971 chr7:2884303 GNA12 0.53 7.92 0.39 3.29e-14 Height; LIHC cis rs4934494 0.727 rs12572012 chr10:91487649 A/T cg19698084 chr10:91461284 KIF20B -0.48 -6.4 -0.33 5.06e-10 Red blood cell count; LIHC cis rs796364 0.806 rs6435041 chr2:200867144 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.79 8.79 0.43 7.61e-17 Schizophrenia; LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg08219700 chr8:58056026 NA 0.53 7.22 0.36 3.36e-12 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.501 rs11683107 chr2:99759235 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 9.9 0.47 1.76e-20 Chronic sinus infection; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg17302176 chr4:139936680 CCRN4L 0.42 6.16 0.32 2e-9 Migraine with aura; LIHC trans rs7618501 0.966 rs13063621 chr3:49821625 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.82 15.14 0.63 5.55e-40 Intelligence (multi-trait analysis); LIHC cis rs5769707 0.656 rs135875 chr22:50012419 T/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.66 -0.42 1.93e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs8060686 0.545 rs8057119 chr16:68268836 C/T cg09835421 chr16:68378352 PRMT7 -0.5 -5.94 -0.31 7.2e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09115837 chr10:79541592 NA 0.41 6.03 0.31 4.15e-9 Pancreatic cancer; LIHC cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg03264133 chr6:25882463 NA 0.56 7.68 0.38 1.65e-13 Blood metabolite levels; LIHC cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.58 0.38 3.34e-13 Bipolar disorder; LIHC cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg26116260 chr4:7069785 GRPEL1 0.98 18.32 0.7 9.86e-53 Monocyte percentage of white cells; LIHC cis rs1122900 1.000 rs1122900 chr5:36689181 A/C cg24186104 chr5:36689192 NA -0.29 -5.88 -0.3 9.5e-9 Aggressive periodontitis; LIHC cis rs903552 0.935 rs4965871 chr15:102003810 A/T cg25677261 chr15:102009856 PCSK6 -0.45 -6.36 -0.33 6.57e-10 Diabetic kidney disease; LIHC cis rs7312774 0.867 rs10492213 chr12:107295841 A/T cg16260113 chr12:107380972 MTERFD3 -0.78 -10.19 -0.48 1.77e-21 Severe influenza A (H1N1) infection; LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg06656553 chr16:89960601 TCF25 -0.49 -6.21 -0.32 1.55e-9 Skin colour saturation; LIHC trans rs1814175 0.645 rs866427 chr11:49923853 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs11785400 1.000 rs4518642 chr8:143737396 T/C cg10596483 chr8:143751796 JRK 0.51 8.26 0.41 3.19e-15 Schizophrenia; LIHC cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.25 -0.45 2.55e-18 Bipolar disorder; LIHC cis rs507080 0.922 rs638805 chr11:118558889 G/T cg04173919 chr11:118528438 PHLDB1 0.35 6.56 0.33 2.01e-10 Serum metabolite levels; LIHC cis rs7940866 0.774 rs10466547 chr11:130823576 T/C cg12179176 chr11:130786555 SNX19 0.62 9.2 0.45 3.52e-18 Schizophrenia; LIHC cis rs780094 0.544 rs2303370 chr2:27651375 C/T cg22903471 chr2:27725779 GCKR -0.44 -7.43 -0.37 8.87e-13 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs11212260 0.512 rs78057192 chr11:107132514 G/A cg25435332 chr11:107328525 CWF19L2 0.75 7.21 0.36 3.66e-12 IgG glycosylation; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg14671364 chr1:107599128 PRMT6 0.48 6.99 0.35 1.45e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg18404041 chr3:52824283 ITIH1 -0.66 -11.06 -0.51 1.61e-24 Bipolar disorder; LIHC trans rs208520 0.690 rs207114 chr6:66791703 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.8 -8.97 -0.44 1.95e-17 Exhaled nitric oxide output; LIHC cis rs7512552 0.839 rs4581308 chr1:150276872 A/G cg15654264 chr1:150340011 RPRD2 -0.7 -11.85 -0.54 2.28e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg17971929 chr21:40555470 PSMG1 0.84 10.07 0.48 4.51e-21 Cognitive function; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09578308 chr8:124780849 FAM91A1 -0.58 -7.55 -0.38 3.94e-13 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs798554 0.959 rs798528 chr7:2772431 A/C cg19717773 chr7:2847554 GNA12 -0.4 -6.41 -0.33 4.95e-10 Height; LIHC cis rs634534 0.562 rs661335 chr11:65754061 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.93 0.43 2.71e-17 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs881375 0.678 rs10760128 chr9:123696325 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.42 0.33 4.46e-10 Rheumatoid arthritis; LIHC trans rs334353 1.000 rs334366 chr9:101929237 A/T cg06788856 chr17:1821969 NA -0.35 -6.24 -0.32 1.29e-9 Age-related macular degeneration; LIHC cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg07061783 chr6:25882402 NA -0.43 -6.07 -0.31 3.41e-9 Blood metabolite levels; LIHC cis rs2067615 0.524 rs4246257 chr12:107062329 C/T cg15890332 chr12:107067104 RFX4 0.27 6.36 0.33 6.32e-10 Heart rate; LIHC cis rs9914988 0.943 rs11658884 chr17:27132742 A/G cg20469991 chr17:27169893 C17orf63 0.59 6.98 0.35 1.54e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs921968 0.541 rs488767 chr2:219466860 G/T cg02985541 chr2:219472218 PLCD4 0.42 6.89 0.35 2.68e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs116095464 0.558 rs10079760 chr5:230778 A/G cg22496380 chr5:211416 CCDC127 -0.95 -9.84 -0.47 2.88e-20 Breast cancer; LIHC cis rs875971 0.964 rs778723 chr7:65829497 T/C cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs6835098 0.962 rs3733477 chr4:174090004 G/A cg27433088 chr4:174089019 GALNT7 0.4 7.34 0.37 1.55e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs2842992 0.830 rs2025189 chr6:160137518 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.54 9.56 0.46 2.49e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs3749237 0.595 rs11130199 chr3:49538799 T/C cg02487422 chr3:49467188 NICN1 0.4 6.25 0.32 1.26e-9 Resting heart rate; LIHC cis rs7945705 0.791 rs10769958 chr11:8815115 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.39 -6.87 -0.35 3.09e-11 Hemoglobin concentration; LIHC cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg17971929 chr21:40555470 PSMG1 0.52 8.05 0.4 1.34e-14 Cognitive function; LIHC cis rs1008375 1.000 rs1558378 chr4:17650351 T/C cg15017067 chr4:17643749 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1707322 0.752 rs6662164 chr1:46146230 T/A cg03146154 chr1:46216737 IPP 0.56 9.82 0.47 3.3e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2576037 0.583 rs8094654 chr18:44527397 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.72 11.26 0.52 3.16e-25 Personality dimensions; LIHC cis rs2952156 0.959 rs2517956 chr17:37843859 G/A cg00129232 chr17:37814104 STARD3 -0.53 -9.68 -0.46 9.32e-20 Asthma; LIHC cis rs986417 0.901 rs1884095 chr14:61017024 C/G cg27398547 chr14:60952738 C14orf39 0.71 7.76 0.39 1.02e-13 Gut microbiota (bacterial taxa); LIHC cis rs8027181 0.839 rs9460 chr15:73044575 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 7.9 0.39 3.83e-14 Triglyceride levels; LIHC cis rs9372253 0.678 rs6568644 chr6:110707820 C/T cg01119278 chr6:110721349 DDO -0.31 -6.56 -0.33 2.03e-10 Platelet distribution width; LIHC cis rs6582630 0.519 rs10880576 chr12:38497693 T/C cg13010199 chr12:38710504 ALG10B 0.43 5.91 0.3 8.32e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs4819052 0.851 rs35871601 chr21:46675214 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.88 0.39 4.55e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg09904177 chr6:26538194 HMGN4 0.57 11.5 0.53 4.35e-26 Intelligence (multi-trait analysis); LIHC cis rs561341 1.000 rs757009 chr17:30243937 A/G cg12193833 chr17:30244370 NA -0.51 -5.79 -0.3 1.56e-8 Hip circumference adjusted for BMI; LIHC trans rs11165623 0.602 rs12120893 chr1:97007132 C/T cg10631902 chr5:14652156 NA -0.25 -6.09 -0.31 3.12e-9 Hip circumference;Waist circumference; LIHC cis rs17401966 0.931 rs3748579 chr1:10420937 C/T cg15208524 chr1:10270712 KIF1B 0.41 6.09 0.31 3.05e-9 Hepatocellular carcinoma; LIHC cis rs11122272 0.732 rs2808605 chr1:231540187 A/C cg06096015 chr1:231504339 EGLN1 0.49 9.07 0.44 9.82e-18 Hemoglobin concentration; LIHC cis rs11098499 0.863 rs11736416 chr4:120431661 C/T cg09307838 chr4:120376055 NA 0.77 11.95 0.54 9.51e-28 Corneal astigmatism; LIHC cis rs17685 0.712 rs28506984 chr7:75763484 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs6754311 0.731 rs748841 chr2:136558157 C/T cg25344623 chr2:136566232 LCT 0.42 8.59 0.42 3.22e-16 Mosquito bite size; LIHC cis rs35272691 1 rs35272691 chr17:38157841 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.78 15.68 0.65 4.06e-42 White blood cell count (neutrophil); LIHC cis rs10792665 0.724 rs10898071 chr11:82727891 C/T cg24227371 chr11:82718527 RAB30 -0.39 -9.65 -0.46 1.17e-19 Obesity-related traits; LIHC cis rs2153535 0.580 rs6937186 chr6:8494493 A/C cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs2033711 0.870 rs7408188 chr19:58939389 T/G cg26874164 chr19:58962979 ZNF324B 0.43 6.01 0.31 4.72e-9 Uric acid clearance; LIHC cis rs6752107 0.967 rs10210302 chr2:234158839 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.1 0.4 9.96e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.86 -0.3 1.11e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9399135 0.967 rs7766189 chr6:135353851 A/C cg22676075 chr6:135203613 NA 0.41 6.74 0.34 6.73e-11 Red blood cell count; LIHC cis rs7829975 0.564 rs2921057 chr8:8318667 C/T cg15556689 chr8:8085844 FLJ10661 0.54 7.99 0.4 2.02e-14 Mood instability; LIHC cis rs4927850 0.881 rs7630489 chr3:195753401 T/C cg12923728 chr3:195709715 SDHAP1 -0.74 -10.61 -0.5 6.46e-23 Pancreatic cancer; LIHC cis rs225245 0.817 rs225255 chr17:33955243 A/G cg05299278 chr17:33885742 SLFN14 -0.23 -6.24 -0.32 1.3e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC trans rs10411161 0.702 rs8113584 chr19:52383874 A/G cg22319618 chr22:45562946 NUP50 -0.6 -8.17 -0.4 6.12e-15 Breast cancer; LIHC cis rs6504663 0.558 rs2412325 chr17:48546232 G/C cg00901687 chr17:48585270 MYCBPAP 0.44 6.62 0.34 1.37e-10 Visceral fat; LIHC cis rs1707322 1.000 rs1768800 chr1:46549188 A/G cg06784218 chr1:46089804 CCDC17 -0.37 -6.74 -0.34 6.8e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.72 11.84 0.54 2.45e-27 Prudent dietary pattern; LIHC trans rs783540 0.656 rs783524 chr15:83284144 A/C cg18393722 chr15:85113863 UBE2QP1 -0.42 -6.64 -0.34 1.27e-10 Schizophrenia; LIHC cis rs921968 0.643 rs4674305 chr2:219293326 C/T cg02985541 chr2:219472218 PLCD4 0.39 7.07 0.36 8.62e-12 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.546 rs1614397 chr11:49913384 G/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs734999 0.588 rs10910099 chr1:2533552 G/T cg18854424 chr1:2615690 NA -0.31 -6.85 -0.35 3.41e-11 Ulcerative colitis; LIHC cis rs10078 1.000 rs10078 chr5:438102 G/T cg07599136 chr5:415885 AHRR 0.62 10.13 0.48 2.81e-21 Fat distribution (HIV); LIHC cis rs6545883 0.859 rs2694644 chr2:61604856 A/T cg14146966 chr2:61757674 XPO1 -0.44 -7.37 -0.37 1.28e-12 Tuberculosis; LIHC cis rs36051895 0.589 rs10491650 chr9:5203054 C/T cg02405213 chr9:5042618 JAK2 0.64 10.75 0.5 2.12e-23 Pediatric autoimmune diseases; LIHC cis rs9910055 0.593 rs58392387 chr17:42297889 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.55 8.15 0.4 6.93e-15 Total body bone mineral density; LIHC trans rs7618501 0.633 rs2008877 chr3:50162291 T/G cg21659725 chr3:3221576 CRBN -0.7 -11.08 -0.51 1.43e-24 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs10939742 chr4:17659936 G/T cg16339924 chr4:17578868 LAP3 0.45 6.23 0.32 1.39e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9640161 0.789 rs2159234 chr7:150020422 A/T cg21361702 chr7:150065534 REPIN1 0.46 6.24 0.32 1.3e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg25072359 chr17:41440525 NA 0.39 6.22 0.32 1.49e-9 Menopause (age at onset); LIHC cis rs2629540 0.544 rs2629529 chr10:126534415 A/C cg08799069 chr10:126477246 METTL10 0.44 6.26 0.32 1.13e-9 Cocaine dependence; LIHC cis rs11628318 0.538 rs1190339 chr14:103103876 C/T cg12046867 chr14:103022105 NA -0.42 -6.65 -0.34 1.18e-10 Platelet count; LIHC cis rs9457247 0.765 rs9457249 chr6:167426438 A/G cg23791538 chr6:167370224 RNASET2 -0.51 -7.76 -0.39 9.79e-14 Crohn's disease; LIHC cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg11764359 chr7:65958608 NA 0.57 6.0 0.31 4.9e-9 Diabetic kidney disease; LIHC cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.06e-10 Alzheimer's disease; LIHC cis rs796364 0.760 rs56285751 chr2:200919836 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs17854409 0.764 rs8116995 chr20:61475824 A/G cg05147244 chr20:61493195 TCFL5 1.18 10.86 0.51 8.1e-24 Obesity-related traits; LIHC trans rs11039798 0.764 rs76882342 chr11:48939091 A/T cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC trans rs75804782 0.641 rs57080728 chr2:239350487 T/C cg01134436 chr17:81009848 B3GNTL1 0.8 6.64 0.34 1.27e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs875971 0.545 rs73150604 chr7:65945532 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.34 6.78 0.34 5.43e-11 Aortic root size; LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg00656387 chr3:40428638 ENTPD3 0.5 8.52 0.42 5.28e-16 Renal cell carcinoma; LIHC cis rs2576037 0.583 rs892586 chr18:44560429 C/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.72 -11.13 -0.52 9.01e-25 Personality dimensions; LIHC cis rs4555082 0.834 rs28846738 chr14:105745781 A/G cg10792982 chr14:105748885 BRF1 0.47 6.32 0.32 7.93e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs3784262 1.000 rs12910113 chr15:58248373 A/C cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.28 -0.32 1e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs8180040 0.726 rs4682837 chr3:46999707 C/T cg02527881 chr3:46936655 PTH1R -0.34 -6.94 -0.35 1.99e-11 Colorectal cancer; LIHC cis rs1348850 0.914 rs10170546 chr2:178248790 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 13.96 0.6 2.22e-35 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs412658 0.812 rs17554725 chr19:22317759 A/G cg05197062 chr11:11642011 GALNTL4 -0.46 -6.44 -0.33 4.05e-10 Telomere length; LIHC cis rs155076 1.000 rs261423 chr13:21852331 A/C cg14456004 chr13:21872349 NA -1.11 -12.36 -0.56 2.88e-29 White matter hyperintensity burden; LIHC cis rs13256369 0.802 rs11249885 chr8:8562008 C/T cg18904891 chr8:8559673 CLDN23 0.78 14.4 0.61 4.49e-37 Obesity-related traits; LIHC cis rs7223966 1.000 rs8073373 chr17:61703320 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 7.1 0.36 7.06e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs67478160 0.634 rs2295140 chr14:104216293 C/T cg08213375 chr14:104286397 PPP1R13B 0.54 10.33 0.49 6.19e-22 Schizophrenia; LIHC cis rs7927592 0.913 rs55883802 chr11:68278829 G/A cg20283391 chr11:68216788 NA -0.52 -7.75 -0.39 1.05e-13 Total body bone mineral density; LIHC cis rs4285028 0.580 rs1523519 chr3:121631841 C/T cg20356878 chr3:121714668 ILDR1 -0.36 -5.72 -0.3 2.29e-8 Multiple sclerosis; LIHC cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg22520471 chr17:61851767 DDX42;CCDC47 -0.57 -8.82 -0.43 6.09e-17 Prudent dietary pattern; LIHC cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg13271783 chr10:134563150 INPP5A -0.59 -7.21 -0.36 3.6e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2115536 0.692 rs6495451 chr15:80164053 C/T cg00225070 chr15:80189496 MTHFS 0.44 7.24 0.36 3.01e-12 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs875971 1.000 rs6945843 chr7:65734783 G/A cg18252515 chr7:66147081 NA 0.42 6.04 0.31 4.13e-9 Aortic root size; LIHC cis rs2439831 0.681 rs528517 chr15:43612925 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.79 11.9 0.54 1.46e-27 Lung cancer in ever smokers; LIHC cis rs1552244 0.572 rs7645759 chr3:10157368 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.64e-23 Alzheimer's disease; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg06873352 chr17:61820015 STRADA -0.74 -13.38 -0.59 3.85e-33 Prudent dietary pattern; LIHC cis rs7903847 0.596 rs11189203 chr10:99159096 C/A cg20016023 chr10:99160130 RRP12 -0.42 -6.74 -0.34 6.73e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg08888203 chr3:10149979 C3orf24 0.52 6.26 0.32 1.14e-9 Alzheimer's disease; LIHC trans rs7618501 0.966 rs9882639 chr3:49799475 A/C cg21665057 chr3:196295764 WDR53;FBXO45 0.81 15.13 0.63 6.04e-40 Intelligence (multi-trait analysis); LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg15383120 chr6:291909 DUSP22 -0.48 -6.49 -0.33 2.95e-10 Menopause (age at onset); LIHC cis rs477895 1.000 rs1047206 chr11:64089216 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 7.01 0.35 1.31e-11 Mean platelet volume; LIHC cis rs6952808 0.792 rs4721184 chr7:1950784 T/C cg20295408 chr7:1910781 MAD1L1 -0.53 -7.51 -0.38 5.08e-13 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.47 0.56 1.09e-29 Prudent dietary pattern; LIHC cis rs12908161 0.959 rs11637728 chr15:85203392 A/T cg03959625 chr15:84868606 LOC388152 0.44 6.07 0.31 3.31e-9 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07562458 chr1:224622430 WDR26 -0.49 -6.48 -0.33 3.16e-10 Pancreatic cancer; LIHC cis rs7223966 1.000 rs8070650 chr17:61744040 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.57 0.33 1.83e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs875971 0.660 rs10950044 chr7:66042976 A/G cg00343986 chr7:65444356 GUSB -0.38 -5.72 -0.3 2.27e-8 Aortic root size; LIHC cis rs2976388 0.590 rs13254346 chr8:143823863 G/C cg06565975 chr8:143823917 SLURP1 -0.42 -7.76 -0.39 1e-13 Urinary tract infection frequency; LIHC cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg03806693 chr22:41940476 POLR3H -0.98 -10.34 -0.49 5.67e-22 Vitiligo; LIHC cis rs2439831 0.850 rs56909447 chr15:44137618 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.7 0.34 8.58e-11 Lung cancer in ever smokers; LIHC cis rs17401966 0.931 rs3737155 chr1:10459779 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.37 -0.33 6.19e-10 Hepatocellular carcinoma; LIHC cis rs11711311 1.000 rs9288982 chr3:113470149 A/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.1 0.44 7.71e-18 IgG glycosylation; LIHC cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.78 -0.39 8.52e-14 Colonoscopy-negative controls vs population controls; LIHC trans rs1814175 0.562 rs1794130 chr11:49903764 T/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg00149659 chr3:10157352 C3orf10 0.69 7.07 0.36 8.52e-12 Alzheimer's disease; LIHC cis rs867186 0.614 rs34526995 chr20:33518834 G/T cg08999081 chr20:33150536 PIGU 0.66 5.93 0.31 7.22e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs10504229 0.679 rs11783557 chr8:58030644 A/G cg20607798 chr8:58055168 NA 0.46 6.71 0.34 7.96e-11 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg05665937 chr4:1216051 CTBP1 -0.45 -5.98 -0.31 5.57e-9 Obesity-related traits; LIHC cis rs1443512 0.812 rs1975472 chr12:54337083 A/G cg25024717 chr12:54324583 NA -0.31 -6.16 -0.32 2.03e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs4665809 0.618 rs7579199 chr2:26266496 G/A cg04944784 chr2:26401820 FAM59B -0.71 -8.95 -0.44 2.25e-17 Gut microbiome composition (summer); LIHC cis rs2072499 0.865 rs2758603 chr1:156198994 T/C cg24450063 chr1:156163899 SLC25A44 0.73 12.59 0.56 3.9e-30 Testicular germ cell tumor; LIHC cis rs7267979 0.932 rs449703 chr20:25458559 C/T cg24626310 chr20:25276739 ABHD12;PYGB 0.45 6.77 0.34 5.56e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs11190604 1.000 rs11190540 chr10:102202629 A/G cg07080220 chr10:102295463 HIF1AN 0.46 6.65 0.34 1.14e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs881375 0.967 rs7034653 chr9:123687372 G/A cg14580859 chr9:123691850 NA 0.4 6.96 0.35 1.79e-11 Rheumatoid arthritis; LIHC cis rs7772486 0.790 rs2265472 chr6:146220758 G/C cg23711669 chr6:146136114 FBXO30 0.63 11.05 0.51 1.77e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs763121 0.853 rs6001204 chr22:39100239 T/C cg21395723 chr22:39101663 GTPBP1 0.4 6.67 0.34 1.04e-10 Menopause (age at onset); LIHC cis rs1670533 0.818 rs585735 chr4:1080391 G/C cg27284194 chr4:1044797 NA 0.6 8.92 0.43 2.8e-17 Recombination rate (females); LIHC cis rs929354 0.772 rs10230895 chr7:157007038 T/C cg16102536 chr7:156981717 UBE3C 0.36 6.06 0.31 3.66e-9 Body mass index; LIHC cis rs4474465 0.790 rs4944206 chr11:78263127 T/C cg27205649 chr11:78285834 NARS2 0.42 6.39 0.33 5.44e-10 Alzheimer's disease (survival time); LIHC cis rs67311347 1.000 rs977652 chr3:40479169 A/G cg18306943 chr3:40428807 ENTPD3 0.33 5.81 0.3 1.45e-8 Renal cell carcinoma; LIHC cis rs6952808 0.771 rs10244946 chr7:1921068 A/G cg20295408 chr7:1910781 MAD1L1 0.5 7.38 0.37 1.24e-12 Bipolar disorder and schizophrenia; LIHC cis rs9486715 0.867 rs4839834 chr6:96882109 C/A cg06623918 chr6:96969491 KIAA0776 0.85 14.74 0.62 2.1e-38 Headache; LIHC trans rs1450439 0.898 rs7697872 chr4:139495443 G/A cg27294979 chr16:69786225 NOB1 0.44 6.41 0.33 4.72e-10 Lung function (forced expiratory volume in 1 second); LIHC cis rs7818688 0.674 rs74632106 chr8:95978032 A/G cg16049864 chr8:95962084 TP53INP1 0.62 6.77 0.34 5.73e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7927592 0.913 rs12283755 chr11:68371658 A/G cg20283391 chr11:68216788 NA -0.48 -7.07 -0.36 8.55e-12 Total body bone mineral density; LIHC cis rs72627509 0.951 rs72606404 chr4:57841213 G/C cg26694713 chr4:57773883 REST 0.67 9.29 0.45 1.91e-18 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs7613875 0.578 rs2624822 chr3:50107219 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.58 -0.34 1.82e-10 Body mass index; LIHC cis rs2839186 0.770 rs2839984 chr21:47671690 A/G cg09417038 chr21:47716443 C21orf57 -0.47 -7.05 -0.36 1e-11 Testicular germ cell tumor; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10633746 chr17:18164442 SMCR7 0.38 6.34 0.32 7.19e-10 Cognitive function; LIHC cis rs1355223 0.583 rs1549789 chr11:34867947 G/A cg11058730 chr11:34937778 PDHX;APIP 0.73 12.62 0.56 2.98e-30 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs67311347 0.955 rs11719205 chr3:40417258 G/A cg16822855 chr3:40428330 ENTPD3 0.32 5.91 0.3 8.44e-9 Renal cell carcinoma; LIHC trans rs2243480 1.000 rs778729 chr7:65824419 T/C cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg27432699 chr2:27873401 GPN1 -0.5 -7.21 -0.36 3.6e-12 Total body bone mineral density; LIHC cis rs2180341 0.924 rs6930849 chr6:127630963 A/T cg27446573 chr6:127587934 RNF146 1.03 16.06 0.66 1.17e-43 Breast cancer; LIHC cis rs4865169 0.560 rs1277312 chr4:57902945 T/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.56 9.49 0.46 4.07e-19 Breast cancer; LIHC cis rs4474465 0.850 rs4245460 chr11:78258147 G/C cg02023728 chr11:77925099 USP35 -0.37 -6.49 -0.33 2.99e-10 Alzheimer's disease (survival time); LIHC cis rs875971 0.862 rs4718377 chr7:66049678 C/T cg18252515 chr7:66147081 NA 0.45 6.57 0.33 1.83e-10 Aortic root size; LIHC cis rs4742903 0.935 rs4743694 chr9:106933163 C/G cg14250997 chr9:106856677 SMC2 0.35 5.91 0.3 8.24e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs13090388 1 rs13090388 chr3:49391082 C/T cg03060546 chr3:49711283 APEH -0.47 -6.4 -0.33 5.1e-10 Intelligence (multi-trait analysis);Educational attainment (years of education); LIHC cis rs933688 1.000 rs6865495 chr5:90746424 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.85 17.99 0.7 2.19e-51 Smoking behavior; LIHC cis rs10791097 0.694 rs10894275 chr11:130756251 C/T cg12179176 chr11:130786555 SNX19 0.85 13.94 0.6 2.63e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9611565 0.921 rs5751077 chr22:41720728 G/C cg03806693 chr22:41940476 POLR3H -0.44 -5.79 -0.3 1.63e-8 Vitiligo; LIHC cis rs12048904 0.541 rs1571046 chr1:101299216 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.67 10.47 0.49 1.91e-22 Multiple sclerosis; LIHC cis rs7918232 0.941 rs4749228 chr10:27433618 C/T cg14442939 chr10:27389572 ANKRD26 -0.74 -7.02 -0.35 1.23e-11 Breast cancer; LIHC cis rs11711311 1.000 rs9865965 chr3:113450495 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.39 0.45 8.39e-19 IgG glycosylation; LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC trans rs1945213 0.694 rs34537090 chr11:55843285 G/C cg03929089 chr4:120376271 NA 0.53 6.91 0.35 2.4e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs644799 1.000 rs563653 chr11:95561488 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs875971 0.660 rs7807944 chr7:66087195 C/G cg11764359 chr7:65958608 NA -0.72 -10.89 -0.51 6.78e-24 Aortic root size; LIHC cis rs7100689 0.784 rs7081903 chr10:82162509 T/C cg01528321 chr10:82214614 TSPAN14 0.92 13.5 0.59 1.32e-33 Post bronchodilator FEV1; LIHC trans rs1814175 0.645 rs1608632 chr11:49967148 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs11122272 0.735 rs2749711 chr1:231537543 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.49 -0.49 1.62e-22 Hemoglobin concentration; LIHC cis rs11945232 1.000 rs4314250 chr4:88340969 A/G cg23841344 chr4:88312519 HSD17B11 0.55 7.43 0.37 9.02e-13 Intelligence (multi-trait analysis); LIHC cis rs637571 0.522 rs1151512 chr11:65757533 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.2 0.45 3.58e-18 Eosinophil percentage of white cells; LIHC cis rs2732480 0.577 rs2732481 chr12:48736985 T/G cg21466736 chr12:48725269 NA -0.72 -11.03 -0.51 2.11e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs17253792 0.822 rs10145687 chr14:56124384 T/C cg01858014 chr14:56050164 KTN1 -0.73 -8.35 -0.41 1.74e-15 Putamen volume; LIHC cis rs7208859 0.524 rs59913838 chr17:29101563 A/T cg13385521 chr17:29058706 SUZ12P 0.84 8.27 0.41 3.06e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 6.13 0.31 2.44e-9 Schizophrenia; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg14004847 chr7:1930337 MAD1L1 -0.47 -6.9 -0.35 2.49e-11 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.63 0.38 2.37e-13 Prudent dietary pattern; LIHC cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg06640241 chr16:89574553 SPG7 0.83 15.35 0.64 8.04e-41 Multiple myeloma (IgH translocation); LIHC cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Bipolar disorder; LIHC cis rs12497850 0.863 rs4858799 chr3:48728204 G/C cg06212747 chr3:49208901 KLHDC8B 0.5 6.43 0.33 4.32e-10 Parkinson's disease; LIHC trans rs11039798 0.588 rs6485869 chr11:48576903 G/T cg15704280 chr7:45808275 SEPT13 0.56 6.23 0.32 1.4e-9 Axial length; LIHC cis rs600806 0.683 rs10857789 chr1:110012293 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.24 -0.32 1.33e-9 Intelligence (multi-trait analysis); LIHC cis rs769267 0.929 rs2905431 chr19:19482882 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.53 -8.13 -0.4 8.08e-15 Tonsillectomy; LIHC cis rs4819052 0.885 rs28576202 chr21:46674684 G/A cg22633049 chr21:46681294 NA -0.36 -6.29 -0.32 9.93e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2072499 0.966 rs2853646 chr1:156189626 C/T cg24450063 chr1:156163899 SLC25A44 1.08 18.16 0.7 4.42e-52 Testicular germ cell tumor; LIHC cis rs807029 0.533 rs67692077 chr10:102740271 T/C cg25179470 chr10:102756915 LZTS2 0.45 6.36 0.32 6.65e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2204008 0.840 rs7957966 chr12:37953629 A/G cg26384229 chr12:38710491 ALG10B -0.48 -6.69 -0.34 9.08e-11 Bladder cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10185667 chr17:66507857 PRKAR1A 0.45 6.14 0.32 2.24e-9 Lung function (FEV1/FVC); LIHC cis rs10985070 0.507 rs12551347 chr9:123936594 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.03 0.31 4.36e-9 Rheumatoid arthritis; LIHC cis rs2629540 0.737 rs10901821 chr10:126480556 T/C cg08799069 chr10:126477246 METTL10 -0.49 -8.24 -0.41 3.61e-15 Cocaine dependence; LIHC cis rs875971 1.000 rs709597 chr7:65825983 A/G cg18252515 chr7:66147081 NA 0.42 6.1 0.31 2.89e-9 Aortic root size; LIHC trans rs1814175 0.588 rs4076322 chr11:49745094 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.59 -0.74 7.56e-62 Height; LIHC cis rs2302190 0.882 rs7221205 chr17:56485799 G/A cg12560992 chr17:57184187 TRIM37 0.64 8.13 0.4 8.05e-15 Vitamin D levels; LIHC cis rs4423214 1.000 rs12278461 chr11:71182185 C/T cg05163923 chr11:71159392 DHCR7 0.8 12.06 0.55 3.81e-28 Vitamin D levels; LIHC cis rs2153535 0.601 rs9379224 chr6:8538413 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.19 0.4 5.35e-15 Motion sickness; LIHC cis rs4253772 0.550 rs9615913 chr22:46668515 A/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.7 -6.36 -0.33 6.59e-10 LDL cholesterol;Cholesterol, total; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07305049 chr22:21354332 THAP7 0.48 6.96 0.35 1.76e-11 Hepatitis; LIHC cis rs6545883 0.929 rs2694625 chr2:61616055 G/A cg15711740 chr2:61764176 XPO1 0.42 5.84 0.3 1.19e-8 Tuberculosis; LIHC cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg25894440 chr7:65020034 NA 0.54 6.18 0.32 1.78e-9 Diabetic kidney disease; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg26338869 chr17:61819248 STRADA 0.59 8.7 0.43 1.42e-16 Prudent dietary pattern; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs11191205 0.774 rs11191203 chr10:103824920 C/T cg15320455 chr10:103880129 LDB1 0.85 7.44 0.37 7.99e-13 Intelligence (multi-trait analysis); LIHC cis rs68170813 0.559 rs3779498 chr7:106923158 C/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs644799 0.562 rs671320 chr11:95578780 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.6 8.64 0.42 2.26e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.99 0.51 2.87e-24 Platelet count; LIHC cis rs7927771 0.524 rs7939420 chr11:47723938 A/G cg20307385 chr11:47447363 PSMC3 -0.7 -10.55 -0.5 1e-22 Subjective well-being; LIHC cis rs1023500 0.551 rs2854837 chr22:42458481 G/A cg15557168 chr22:42548783 NA -0.43 -6.71 -0.34 8.24e-11 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21784052 chr20:47835958 DDX27 -0.45 -6.27 -0.32 1.11e-9 Pancreatic cancer; LIHC cis rs7772486 0.790 rs2253307 chr6:146196181 T/G cg05347473 chr6:146136440 FBXO30 0.37 6.06 0.31 3.64e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11931598 0.514 rs10937779 chr4:7039326 G/A cg19539972 chr4:7069911 GRPEL1 0.48 7.92 0.39 3.47e-14 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs3770081 0.590 rs11891333 chr2:86178394 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.75 -8.67 -0.42 1.72e-16 Facial emotion recognition (sad faces); LIHC cis rs273218 0.694 rs274369 chr5:53379987 G/C ch.5.1024479R chr5:53302184 ARL15 0.55 8.97 0.44 1.97e-17 Migraine; LIHC cis rs2629540 1.000 rs2629540 chr10:126426148 G/C cg20435097 chr10:126320824 FAM53B -0.43 -6.23 -0.32 1.39e-9 Cocaine dependence; LIHC cis rs12908161 1.000 rs34570071 chr15:85280212 T/A cg12863693 chr15:85201151 NMB 0.47 6.76 0.34 5.88e-11 Schizophrenia; LIHC cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg11890956 chr21:40555474 PSMG1 1.0 14.18 0.61 3.28e-36 Cognitive function; LIHC cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.69 9.52 0.46 3.23e-19 Alzheimer's disease; LIHC cis rs8180040 1.000 rs1638676 chr3:47327651 A/G cg02527881 chr3:46936655 PTH1R -0.3 -5.89 -0.3 9.21e-9 Colorectal cancer; LIHC cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg13397359 chr6:42928475 GNMT 0.64 9.31 0.45 1.56e-18 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9467711 0.606 rs13203358 chr6:26590578 A/T cg09904177 chr6:26538194 HMGN4 -0.53 -5.76 -0.3 1.83e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg21724239 chr8:58056113 NA 0.57 7.5 0.38 5.53e-13 Developmental language disorder (linguistic errors); LIHC cis rs240764 0.853 rs12190903 chr6:100983505 C/T cg09795085 chr6:101329169 ASCC3 -0.45 -6.26 -0.32 1.16e-9 Neuroticism; LIHC cis rs4638749 0.654 rs6761157 chr2:108816885 A/C cg06795125 chr2:108905320 SULT1C2 -0.29 -5.75 -0.3 1.94e-8 Blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20617956 chr10:82168530 C10orf58 0.46 6.43 0.33 4.22e-10 Pancreatic cancer; LIHC cis rs2839186 0.587 rs35679325 chr21:47640980 A/G cg00612595 chr21:47717864 NA 0.35 5.88 0.3 9.55e-9 Testicular germ cell tumor; LIHC cis rs11958404 0.860 rs72818111 chr5:157438361 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs62103177 0.673 rs62096717 chr18:77616819 C/T cg05926928 chr17:57297772 GDPD1 0.57 7.71 0.38 1.41e-13 Opioid sensitivity; LIHC cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg18230493 chr5:56204884 C5orf35 -0.45 -6.16 -0.32 2.04e-9 Initial pursuit acceleration; LIHC cis rs2842992 1.000 rs2842992 chr6:160071159 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.47 7.81 0.39 7.1e-14 Age-related macular degeneration (geographic atrophy); LIHC cis rs3768617 0.510 rs3768615 chr1:183103604 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.44 0.49 2.46e-22 Fuchs's corneal dystrophy; LIHC cis rs4728302 0.534 rs6976069 chr7:133152898 T/C cg10665199 chr7:133106180 EXOC4 0.5 8.47 0.42 7.51e-16 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs61990749 0.597 rs12896026 chr14:78244436 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.26 0.49 1e-21 Fibroblast growth factor basic levels; LIHC cis rs11030122 0.673 rs10835474 chr11:4020819 G/T cg18678763 chr11:4115507 RRM1 -0.57 -8.38 -0.41 1.37e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs2425143 1.000 rs60646509 chr20:34303409 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs8180040 0.726 rs6785790 chr3:47146932 C/T cg27129171 chr3:47204927 SETD2 0.68 11.92 0.54 1.25e-27 Colorectal cancer; LIHC cis rs13394619 0.620 rs11674184 chr2:11721535 T/G cg07314298 chr2:11723111 GREB1 -0.6 -11.47 -0.53 5.26e-26 Endometriosis; LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg22029157 chr1:209979665 IRF6 0.5 8.13 0.4 7.78e-15 Cleft lip with or without cleft palate; LIHC cis rs7208859 0.623 rs7223209 chr17:29107220 C/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs5758511 0.689 rs56906457 chr22:42628335 A/G cg00645731 chr22:42541494 CYP2D7P1 0.59 5.8 0.3 1.55e-8 Birth weight; LIHC cis rs2070488 0.965 rs2366119 chr3:38484453 C/T cg24069376 chr3:38537580 EXOG 0.43 7.85 0.39 5.33e-14 Electrocardiographic conduction measures; LIHC cis rs1448094 0.512 rs7299285 chr12:86244959 A/T cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs12478296 1.000 rs66612947 chr2:243035962 A/T cg18898632 chr2:242989856 NA -0.59 -8.01 -0.4 1.81e-14 Obesity-related traits; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04282497 chr4:82350883 RASGEF1B 0.4 6.04 0.31 4.12e-9 Longevity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00271154 chr2:113033418 ZC3H6 0.42 6.87 0.35 3.09e-11 Pancreatic cancer; LIHC trans rs7618501 0.669 rs3774758 chr3:49938227 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.61 9.66 0.46 1.12e-19 Intelligence (multi-trait analysis); LIHC cis rs9296092 0.538 rs5000098 chr6:33519231 T/G cg13560919 chr6:33536144 NA -0.38 -6.44 -0.33 4.1e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs3015497 0.616 rs10131107 chr14:51062455 G/A cg09863266 chr14:51125203 SAV1 -0.38 -5.99 -0.31 5.36e-9 Mean platelet volume; LIHC cis rs713477 0.935 rs4901567 chr14:55912698 C/T cg13175173 chr14:55914753 NA -0.33 -7.61 -0.38 2.68e-13 Pediatric bone mineral content (femoral neck); LIHC cis rs3008870 0.755 rs2815366 chr1:67499930 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.66 11.31 0.52 2.03e-25 Lymphocyte percentage of white cells; LIHC cis rs9611565 0.506 rs4822020 chr22:41700203 C/T cg06634786 chr22:41940651 POLR3H -0.53 -6.26 -0.32 1.17e-9 Vitiligo; LIHC cis rs936229 0.749 rs6495126 chr15:75175026 C/T cg10253484 chr15:75165896 SCAMP2 0.58 6.9 0.35 2.58e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC trans rs8030605 0.778 rs72740578 chr15:56638096 G/A cg01710580 chr16:598674 SOLH -0.66 -6.09 -0.31 3.08e-9 Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7246865 0.859 rs7252102 chr19:17197012 A/G cg16202187 chr19:17186497 HAUS8;MYO9B 0.4 6.09 0.31 2.99e-9 Reticulocyte fraction of red cells; LIHC cis rs2710642 0.586 rs6545961 chr2:62814166 A/T cg17519650 chr2:63277830 OTX1 0.45 7.1 0.36 7.43e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.42 0.62 3.58e-37 Prudent dietary pattern; LIHC cis rs7546668 1.000 rs4233535 chr1:15845197 G/C cg11706911 chr1:15910989 AGMAT 0.44 6.82 0.35 4.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs7095607 0.704 rs34869044 chr10:69953763 C/T cg18986048 chr10:69913749 MYPN 0.43 6.53 0.33 2.36e-10 Lung function (FVC); LIHC trans rs7922314 1.000 rs10995340 chr10:64632908 G/A cg06816054 chr8:27695695 PBK 0.56 6.22 0.32 1.48e-9 Cutaneous psoriasis; LIHC cis rs9911578 1.000 rs2567905 chr17:56782297 T/C cg05425664 chr17:57184151 TRIM37 -0.58 -8.49 -0.42 6.46e-16 Intelligence (multi-trait analysis); LIHC cis rs7904368 0.754 rs7091240 chr10:16855683 G/A cg14835575 chr10:16859367 RSU1 0.65 9.01 0.44 1.46e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs12048904 0.964 rs3188491 chr1:101338482 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.54 8.59 0.42 3.17e-16 Multiple sclerosis; LIHC cis rs708547 0.836 rs1718882 chr4:57859533 C/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.81 14.79 0.62 1.31e-38 Response to bleomycin (chromatid breaks); LIHC cis rs1799949 1.000 rs11659028 chr17:41195025 T/A cg23758822 chr17:41437982 NA 0.92 16.62 0.67 7e-46 Menopause (age at onset); LIHC cis rs6939532 0.522 rs6933583 chr6:26355283 A/C cg14345882 chr6:26364793 BTN3A2 0.39 5.95 0.31 6.64e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs4853012 0.941 rs7571083 chr2:74342260 C/G cg20011983 chr2:74347215 NA -0.4 -5.89 -0.3 9.15e-9 Gestational age at birth (maternal effect); LIHC cis rs1691799 0.899 rs1168318 chr12:66745269 A/G cg16791601 chr12:66731901 HELB 0.59 14.69 0.62 3.26e-38 White blood cell count (basophil); LIHC cis rs74544699 1.000 rs77149208 chr4:74768731 C/A cg02530824 chr4:74847766 PF4 0.66 6.88 0.35 2.83e-11 Growth-regulated protein alpha levels; LIHC trans rs875971 0.545 rs10950027 chr7:65634151 C/T cg26939375 chr7:64535504 NA 0.4 6.42 0.33 4.54e-10 Aortic root size; LIHC cis rs6570726 0.935 rs369214 chr6:145856709 G/A cg23711669 chr6:146136114 FBXO30 0.56 10.03 0.48 6.55e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.95 -0.31 6.54e-9 Menopause (age at onset); LIHC cis rs2576037 0.526 rs9962523 chr18:44486414 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 10.15 0.48 2.52e-21 Personality dimensions; LIHC cis rs8141529 0.509 rs6005927 chr22:29255884 A/G cg15103426 chr22:29168792 CCDC117 0.66 10.42 0.49 2.95e-22 Lymphocyte counts; LIHC cis rs4953318 0.619 rs13406901 chr2:46363066 T/G cg12428440 chr2:46370979 PRKCE 0.46 6.28 0.32 1.02e-9 Red blood cell count;Hematocrit;Red blood cell traits; LIHC cis rs2380220 0.678 rs4308568 chr6:96009525 A/C cg15832292 chr6:96025679 MANEA -0.58 -7.72 -0.39 1.27e-13 Behavioural disinhibition (generation interaction); LIHC cis rs11690935 0.632 rs34242651 chr2:172553999 G/A cg13550731 chr2:172543902 DYNC1I2 0.63 11.8 0.54 3.38e-27 Schizophrenia; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg24452005 chr18:9913478 VAPA -0.43 -6.11 -0.31 2.67e-9 Bipolar disorder; LIHC cis rs780096 0.565 rs11681351 chr2:27743423 G/A cg27432699 chr2:27873401 GPN1 -0.6 -8.52 -0.42 5.34e-16 Total body bone mineral density; LIHC trans rs11039798 0.588 rs6485891 chr11:48612024 T/A cg15704280 chr7:45808275 SEPT13 0.57 6.32 0.32 7.99e-10 Axial length; LIHC cis rs7223966 1.000 rs752621 chr17:61901880 G/C cg05941027 chr17:61774174 LIMD2 0.37 7.78 0.39 8.77e-14 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9649213 0.593 rs35941058 chr7:97918159 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs738321 0.757 rs4820314 chr22:38518538 G/A cg25457927 chr22:38595422 NA -0.33 -7.58 -0.38 3.23e-13 Breast cancer; LIHC cis rs10078 0.528 rs2434697 chr5:466811 T/C cg08916839 chr5:415575 AHRR 0.6 12.67 0.57 2.03e-30 Fat distribution (HIV); LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07562135 chr19:39340654 HNRNPL 0.5 6.51 0.33 2.61e-10 Hepatitis; LIHC cis rs8005677 1.000 rs8006396 chr14:23380850 A/G cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs992157 0.730 rs2382828 chr2:219184492 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.21 0.48 1.49e-21 Colorectal cancer; LIHC cis rs9457247 0.765 rs9457259 chr6:167444281 C/T cg12798992 chr6:167411361 FGFR1OP 0.48 7.18 0.36 4.3e-12 Crohn's disease; LIHC cis rs67478160 0.583 rs12879612 chr14:104233618 T/A cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.22 -0.36 3.4e-12 Schizophrenia; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg10799249 chr10:422187 DIP2C 0.4 6.29 0.32 9.48e-10 Electroencephalogram traits; LIHC cis rs317689 0.690 rs607797 chr12:69646010 T/C cg14784868 chr12:69753453 YEATS4 0.52 7.34 0.37 1.59e-12 Response to diuretic therapy; LIHC cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg24531977 chr5:56204891 C5orf35 -0.66 -9.43 -0.45 6.3e-19 Initial pursuit acceleration; LIHC trans rs2727020 0.521 rs7114564 chr11:49571231 C/T cg18944383 chr4:111397179 ENPEP -0.36 -8.17 -0.4 6.22e-15 Coronary artery disease; LIHC trans rs7246657 1.000 rs6508710 chr19:37749886 A/G cg10208301 chr11:6592745 DNHD1 0.45 6.4 0.33 5.12e-10 Coronary artery calcification; LIHC cis rs7572733 0.534 rs700682 chr2:198712310 C/A cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24914313 chr13:41636195 WBP4 0.44 6.33 0.32 7.86e-10 Pancreatic cancer; LIHC cis rs238295 0.805 rs6053525 chr20:5577000 C/T cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -6.95 -0.35 1.83e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs4243830 0.850 rs13513 chr1:6585804 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.82 -10.15 -0.48 2.52e-21 Body mass index; LIHC cis rs875971 1.000 rs35149210 chr7:65929925 T/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs8044995 0.563 rs8059585 chr16:68376811 G/A cg09835421 chr16:68378352 PRMT7 -0.81 -9.77 -0.47 4.67e-20 Schizophrenia; LIHC cis rs317689 0.581 rs160829 chr12:69769538 G/C cg22834771 chr12:69754056 YEATS4 -0.47 -7.99 -0.4 2.03e-14 Response to diuretic therapy; LIHC cis rs1823913 0.599 rs13027086 chr2:192158784 A/G cg12404831 chr2:192114017 MYO1B 0.28 5.76 0.3 1.85e-8 Obesity-related traits; LIHC cis rs35146811 0.806 rs1534310 chr7:99699169 A/T cg22906224 chr7:99728672 NA 0.43 5.98 0.31 5.51e-9 Coronary artery disease; LIHC cis rs11931598 0.782 rs4689581 chr4:7048134 C/T cg26116260 chr4:7069785 GRPEL1 -0.43 -6.92 -0.35 2.2e-11 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs4561483 0.832 rs33645 chr16:11985201 T/C cg08843971 chr16:11963173 GSPT1 -0.43 -8.5 -0.42 5.76e-16 Testicular germ cell tumor; LIHC trans rs875971 0.638 rs10249404 chr7:66046724 G/A cg26939375 chr7:64535504 NA -0.43 -6.98 -0.35 1.57e-11 Aortic root size; LIHC cis rs600806 0.888 rs638542 chr1:109845252 G/A cg16275483 chr1:110013120 SYPL2 -0.51 -6.19 -0.32 1.7e-9 Intelligence (multi-trait analysis); LIHC cis rs9811920 0.609 rs4244713 chr3:99679584 T/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.8 -0.3 1.48e-8 Axial length; LIHC cis rs72781680 1.000 rs12617839 chr2:24166277 A/T cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs7772486 0.692 rs1577916 chr6:146069789 G/A cg23711669 chr6:146136114 FBXO30 -0.73 -13.51 -0.59 1.28e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs539514 0.690 rs2328953 chr13:76317459 T/G cg04757411 chr13:76259545 LMO7 -0.45 -8.03 -0.4 1.61e-14 Type 1 diabetes; LIHC cis rs67460515 0.892 rs34771618 chr3:161059795 A/C cg03342759 chr3:160939853 NMD3 -0.58 -8.59 -0.42 3.2e-16 Parkinson's disease; LIHC cis rs365132 0.875 rs353494 chr5:176431759 C/G cg16309518 chr5:176445507 NA -0.53 -9.96 -0.47 1.06e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC trans rs72960926 0.744 rs72952257 chr6:74924073 A/G cg07247405 chr1:2484626 LOC115110 0.56 6.62 0.34 1.36e-10 Metabolite levels (MHPG); LIHC cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.86 0.35 3.15e-11 Gut microbiome composition (summer); LIHC cis rs61990749 0.544 rs176962 chr14:78185510 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.2 0.48 1.72e-21 Fibroblast growth factor basic levels; LIHC cis rs963731 0.649 rs10183915 chr2:39218887 A/T cg04010122 chr2:39346883 SOS1 -0.79 -6.04 -0.31 3.97e-9 Corticobasal degeneration; LIHC cis rs2067615 0.579 rs7297592 chr12:107223969 G/T cg15890332 chr12:107067104 RFX4 0.27 6.21 0.32 1.57e-9 Heart rate; LIHC cis rs7044106 0.791 rs735110 chr9:123488940 T/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.58 8.87 0.43 4.24e-17 Hip circumference adjusted for BMI; LIHC cis rs826838 0.900 rs11169301 chr12:39128497 C/A cg26384229 chr12:38710491 ALG10B 0.86 11.06 0.51 1.63e-24 Heart rate; LIHC cis rs3736485 0.868 rs8023455 chr15:51936510 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -5.95 -0.31 6.66e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12477438 0.834 rs1563107 chr2:99701276 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.73 10.67 0.5 3.84e-23 Chronic sinus infection; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg06873352 chr17:61820015 STRADA 0.54 8.04 0.4 1.49e-14 Height; LIHC cis rs8141529 0.719 rs6005916 chr22:29233342 T/C cg02153584 chr22:29168773 CCDC117 0.58 9.19 0.44 3.92e-18 Lymphocyte counts; LIHC cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.04 0.55 4.36e-28 Alzheimer's disease; LIHC cis rs933688 1.000 rs10059163 chr5:90742444 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 21.11 0.75 6.65e-64 Smoking behavior; LIHC cis rs875971 0.798 rs6460304 chr7:65964728 G/A cg11764359 chr7:65958608 NA 0.85 15.31 0.64 1.2e-40 Aortic root size; LIHC cis rs1801251 1.000 rs12478564 chr2:233598340 C/T cg25237894 chr2:233734115 C2orf82 0.58 11.22 0.52 4.42e-25 Coronary artery disease; LIHC cis rs6840360 1.000 rs12331037 chr4:152663971 G/A cg22705602 chr4:152727874 NA -0.34 -7.24 -0.36 2.94e-12 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.13 -0.44 6.13e-18 Bipolar disorder; LIHC cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg23758822 chr17:41437982 NA 0.94 17.49 0.69 2.15e-49 Menopause (age at onset); LIHC cis rs2180341 0.855 rs9385422 chr6:127716457 C/T cg27446573 chr6:127587934 RNF146 0.81 13.37 0.59 4.38e-33 Breast cancer; LIHC trans rs875971 0.619 rs12533585 chr7:65984605 G/C cg26939375 chr7:64535504 NA 0.43 6.94 0.35 2.02e-11 Aortic root size; LIHC cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg16325326 chr1:53192061 ZYG11B -0.4 -6.78 -0.34 5.24e-11 Monocyte count; LIHC cis rs1215050 0.740 rs185468 chr4:98756242 C/T cg05340658 chr4:99064831 C4orf37 0.39 5.79 0.3 1.62e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1355223 0.583 rs1549789 chr11:34867947 G/A cg24088639 chr11:34937564 PDHX;APIP -0.39 -5.97 -0.31 5.98e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs9649465 1.000 rs2896334 chr7:123367705 A/C cg03229431 chr7:123269106 ASB15 -0.38 -8.06 -0.4 1.25e-14 Migraine; LIHC cis rs9596863 1.000 rs4471558 chr13:54413349 A/T ch.13.53330881F chr13:54432880 NA 0.43 6.09 0.31 3.06e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9457247 0.663 rs10946205 chr6:167451311 A/G cg12798992 chr6:167411361 FGFR1OP 0.53 8.74 0.43 1.04e-16 Crohn's disease; LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 11.63 0.53 1.42e-26 Height; LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg11494091 chr17:61959527 GH2 0.45 8.32 0.41 2.12e-15 Prudent dietary pattern; LIHC cis rs7238033 0.641 rs11877028 chr18:43317866 C/G cg20610511 chr18:43302872 SLC14A1 0.39 6.47 0.33 3.3e-10 Bladder cancer; LIHC cis rs17253792 0.822 rs76819679 chr14:56134672 C/G cg01858014 chr14:56050164 KTN1 -0.66 -6.75 -0.34 6.43e-11 Putamen volume; LIHC cis rs10751667 0.925 rs7115336 chr11:988101 C/G cg06064525 chr11:970664 AP2A2 -0.49 -12.17 -0.55 1.42e-28 Alzheimer's disease (late onset); LIHC cis rs919433 0.713 rs6714697 chr2:198484486 C/T cg03934865 chr2:198174659 NA 0.51 7.72 0.39 1.3e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs700651 0.789 rs1147169 chr2:198901395 C/T cg03934865 chr2:198174659 NA -0.46 -6.4 -0.33 5.19e-10 Intracranial aneurysm; LIHC cis rs11252926 0.545 rs1551508 chr10:555469 A/G cg09445902 chr10:555545 DIP2C -0.4 -6.49 -0.33 3.1e-10 Psychosis in Alzheimer's disease; LIHC cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg18230493 chr5:56204884 C5orf35 0.45 6.21 0.32 1.53e-9 Initial pursuit acceleration; LIHC cis rs1577917 0.727 rs9344539 chr6:86353621 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.63 -0.42 2.4e-16 Response to antipsychotic treatment; LIHC cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg21724239 chr8:58056113 NA 0.49 6.41 0.33 4.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs950776 0.518 rs12594391 chr15:78816240 A/G cg22563815 chr15:78856949 CHRNA5 0.35 6.4 0.33 5.07e-10 Sudden cardiac arrest; LIHC cis rs7116495 0.609 rs10793014 chr11:71698838 A/G cg26138937 chr11:71823887 C11orf51 -1.28 -10.0 -0.48 8.22e-21 Severe influenza A (H1N1) infection; LIHC cis rs7296418 0.961 rs949143 chr12:123595163 G/A cg00376283 chr12:123451042 ABCB9 0.74 13.15 0.58 3.05e-32 Platelet count; LIHC cis rs2404602 0.692 rs1838048 chr15:76931679 A/G cg03037974 chr15:76606532 NA 0.74 14.45 0.62 2.79e-37 Blood metabolite levels; LIHC trans rs3960554 1.000 rs78663390 chr7:75845837 C/A cg19862616 chr7:65841803 NCRNA00174 0.61 9.05 0.44 1.11e-17 Eotaxin levels; LIHC cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC trans rs561341 1.000 rs483301 chr17:30293398 G/T cg20587970 chr11:113659929 NA -1.46 -11.99 -0.54 6.92e-28 Hip circumference adjusted for BMI; LIHC trans rs2504916 0.830 rs2504934 chr6:160781666 A/G cg08119480 chr6:150067491 NUP43 -0.47 -6.03 -0.31 4.17e-9 Response to hepatitis C treatment; LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.02e-13 Prudent dietary pattern; LIHC cis rs11245387 0.564 rs7915429 chr10:126510089 T/C cg08799069 chr10:126477246 METTL10 -0.44 -6.75 -0.34 6.49e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs17685 0.753 rs4732542 chr7:75663203 A/G cg16684958 chr7:75615977 POR 0.49 8.57 0.42 3.56e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs875971 0.660 rs3857686 chr7:66036191 C/T cg00343986 chr7:65444356 GUSB -0.4 -5.99 -0.31 5.42e-9 Aortic root size; LIHC cis rs10791097 0.608 rs12363140 chr11:130744268 A/C cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11229555 1.000 rs12799215 chr11:58405674 C/T cg15696309 chr11:58395628 NA -0.72 -8.87 -0.43 4.15e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4746818 1.000 rs7091695 chr10:70964997 A/G cg11621586 chr10:70884670 VPS26A -0.82 -11.53 -0.53 3.19e-26 Left atrial antero-posterior diameter; LIHC cis rs2777491 0.574 rs72739644 chr15:41719706 A/G cg18705301 chr15:41695430 NDUFAF1 -1.26 -18.71 -0.71 2.75e-54 Ulcerative colitis; LIHC cis rs11583043 0.958 rs12730160 chr1:101438791 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.14 0.4 7.31e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs142518269 1 rs142518269 chr2:24087095 G/A cg08917208 chr2:24149416 ATAD2B 0.99 8.7 0.43 1.39e-16 Mean corpuscular hemoglobin; LIHC cis rs10861342 0.579 rs77585712 chr12:105482251 T/C cg23923672 chr12:105501055 KIAA1033 0.65 7.48 0.38 6.2800000000000005e-13 IgG glycosylation; LIHC cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg02034447 chr16:89574710 SPG7 -0.48 -7.53 -0.38 4.71e-13 Multiple myeloma (IgH translocation); LIHC cis rs7772486 0.701 rs11155438 chr6:145950112 C/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.38 -0.33 5.61e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1941023 0.503 rs7952244 chr11:60132164 G/A cg08716584 chr11:60157161 MS4A7 -0.35 -8.12 -0.4 8.76e-15 Congenital heart disease (maternal effect); LIHC cis rs1707322 0.963 rs9787412 chr1:46371596 C/T cg03146154 chr1:46216737 IPP 0.47 7.66 0.38 1.88e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg12016809 chr21:47604291 C21orf56 0.47 7.25 0.36 2.83e-12 Testicular germ cell tumor; LIHC cis rs270601 0.770 rs932019 chr5:131599370 T/C cg24060327 chr5:131705240 SLC22A5 -0.53 -6.9 -0.35 2.48e-11 Acylcarnitine levels; LIHC cis rs10876993 0.928 rs1689594 chr12:58057156 T/C cg15848620 chr12:58087721 OS9 -0.54 -7.42 -0.37 9.2e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs9457247 1.000 rs2769352 chr6:167378619 A/G cg12798992 chr6:167411361 FGFR1OP -0.54 -8.28 -0.41 2.76e-15 Crohn's disease; LIHC cis rs875971 0.862 rs11760844 chr7:65739883 C/G cg11764359 chr7:65958608 NA -0.85 -15.03 -0.63 1.49e-39 Aortic root size; LIHC cis rs8114671 0.562 rs34837802 chr20:33424908 C/G cg07148914 chr20:33460835 GGT7 0.61 9.3 0.45 1.74e-18 Height; LIHC cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg22105103 chr4:187893119 NA 0.3 7.14 0.36 5.63e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.88 7.96 0.4 2.52e-14 Platelet count; LIHC cis rs743757 1.000 rs2236964 chr3:50449062 C/G cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.44 -6.14 -0.32 2.24e-9 Diastolic blood pressure; LIHC cis rs8180040 0.764 rs4082155 chr3:47125385 G/A cg02527881 chr3:46936655 PTH1R -0.31 -6.05 -0.31 3.72e-9 Colorectal cancer; LIHC cis rs7296418 0.675 rs1879379 chr12:123727443 G/A cg05973401 chr12:123451056 ABCB9 0.43 6.39 0.33 5.58e-10 Platelet count; LIHC cis rs3733346 0.553 rs6813110 chr4:942660 C/T cg20456258 chr4:962124 DGKQ 0.36 6.96 0.35 1.77e-11 Sjögren's syndrome; LIHC cis rs17106184 1.000 rs59097691 chr1:51394098 C/T cg07174182 chr1:51127561 FAF1 -0.74 -8.35 -0.41 1.69e-15 Type 2 diabetes; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg20295408 chr7:1910781 MAD1L1 -0.48 -6.99 -0.35 1.41e-11 Bipolar disorder and schizophrenia; LIHC cis rs523522 0.962 rs687873 chr12:121019634 G/A cg27279351 chr12:120934652 DYNLL1 0.68 11.96 0.54 8.87e-28 High light scatter reticulocyte count; LIHC cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.64e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 1.000 rs66479724 chr8:58188309 T/G cg02290350 chr8:58132656 NA 0.38 7.94 0.39 2.87e-14 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.89 -10.59 -0.5 7.75e-23 Platelet count; LIHC cis rs17106184 0.892 rs58029717 chr1:51162128 A/G cg07174182 chr1:51127561 FAF1 -0.63 -6.74 -0.34 6.82e-11 Type 2 diabetes; LIHC cis rs6748734 1.000 rs11898716 chr2:241828311 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -7.97 -0.4 2.32e-14 Urinary metabolites; LIHC cis rs1113500 0.636 rs3853493 chr1:108637193 G/A cg06207961 chr1:108661230 NA 0.31 5.99 0.31 5.21e-9 Growth-regulated protein alpha levels; LIHC cis rs1144333 0.655 rs7418941 chr1:76436020 A/G cg22875332 chr1:76189707 ACADM 0.41 6.19 0.32 1.69e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs208515 0.525 rs10944863 chr6:66676238 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.75 8.71 0.43 1.36e-16 Exhaled nitric oxide levels; LIHC cis rs10504229 1.000 rs10504229 chr8:58196495 A/G cg02290350 chr8:58132656 NA 0.47 9.11 0.44 7.19e-18 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.520 rs13022329 chr2:99731189 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.88 15.82 0.65 1.09e-42 Chronic sinus infection; LIHC cis rs2274273 1.000 rs2274273 chr14:55614636 A/G cg01864836 chr14:55583639 NA 0.36 6.24 0.32 1.32e-9 Protein biomarker; LIHC cis rs9733 0.596 rs12063547 chr1:150674053 G/T cg18016565 chr1:150552671 MCL1 -0.58 -11.52 -0.53 3.53e-26 Tonsillectomy; LIHC cis rs2439831 0.850 rs28476182 chr15:44139643 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.7 0.34 8.58e-11 Lung cancer in ever smokers; LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg06873352 chr17:61820015 STRADA 0.75 13.24 0.58 1.32e-32 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03694515 chr18:32870085 ZNF271;ZNF397OS 0.46 7.3 0.37 2.02e-12 Pancreatic cancer; LIHC cis rs10751667 1.000 rs10751667 chr11:941941 A/T ch.11.42038R chr11:967971 AP2A2 0.57 10.41 0.49 3.26e-22 Alzheimer's disease (late onset); LIHC cis rs912057 1.000 rs1294414 chr6:6740366 A/G cg06612196 chr6:6737390 NA 0.51 9.28 0.45 2.05e-18 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs12079745 0.793 rs10800443 chr1:169355529 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -6.83 -0.35 3.83e-11 QT interval; LIHC cis rs10411936 0.692 rs3810196 chr19:16601154 T/C cg10248733 chr19:16607483 C19orf44;CALR3 0.48 6.5 0.33 2.92e-10 White blood cell count;Multiple sclerosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13006718 chr18:33078008 INO80C 0.48 6.86 0.35 3.2e-11 Pancreatic cancer; LIHC cis rs6754311 0.593 rs55825471 chr2:136526981 T/A cg25344623 chr2:136566232 LCT 0.44 8.88 0.43 3.96e-17 Mosquito bite size; LIHC cis rs10870270 1.000 rs4880246 chr10:133764064 C/T cg26149184 chr10:133730230 NA 0.47 7.47 0.37 6.93e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg09222892 chr1:25734099 RHCE -0.43 -7.91 -0.39 3.61e-14 Plateletcrit;Mean corpuscular volume; LIHC cis rs11190604 0.767 rs79106148 chr10:102184732 G/A cg07080220 chr10:102295463 HIF1AN 0.47 6.87 0.35 3.04e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs600806 0.713 rs11102984 chr1:109997373 T/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.83 -0.3 1.27e-8 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.673 rs9891179 chr17:29208160 G/T cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6502050 0.835 rs7502078 chr17:80131879 C/A cg11859384 chr17:80120422 CCDC57 -0.44 -6.0 -0.31 5.01e-9 Life satisfaction; LIHC cis rs7824557 0.591 rs2572452 chr8:11228254 C/T cg21775007 chr8:11205619 TDH -0.63 -9.78 -0.47 4.28e-20 Retinal vascular caliber; LIHC cis rs2066819 1.000 rs1802236 chr12:56679751 A/G cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs1506636 0.962 rs10243279 chr7:123441262 T/A cg03229431 chr7:123269106 ASB15 0.5 8.29 0.41 2.7e-15 Plateletcrit;Platelet count; LIHC cis rs4930103 0.935 rs4930110 chr11:2026701 G/C cg06197492 chr11:2016605 H19 0.39 6.11 0.31 2.64e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC trans rs800082 0.698 rs800077 chr3:144349940 A/G cg24215973 chr2:240111563 HDAC4 -0.61 -9.25 -0.45 2.52e-18 Smoking behavior; LIHC cis rs7589728 0.563 rs78168096 chr2:88473575 G/A cg04511125 chr2:88470314 THNSL2 0.97 9.87 0.47 2.22e-20 Plasma clusterin levels; LIHC cis rs1670533 1.000 rs10084889 chr4:1053815 G/A cg27284194 chr4:1044797 NA 0.6 8.95 0.44 2.33e-17 Recombination rate (females); LIHC cis rs7309 0.935 rs10930013 chr2:162070325 G/A cg08807892 chr2:162101083 NA 0.45 7.64 0.38 2.14e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC trans rs61931739 0.500 rs11053167 chr12:34387092 A/C cg26384229 chr12:38710491 ALG10B 0.76 9.32 0.45 1.49e-18 Morning vs. evening chronotype; LIHC cis rs807669 0.903 rs807668 chr22:19162686 A/G cg02655711 chr22:19163373 SLC25A1 0.75 11.53 0.53 3.35e-26 Metabolite levels; LIHC cis rs3784262 0.679 rs4238326 chr15:58336000 C/T cg12031962 chr15:58353849 ALDH1A2 0.33 6.13 0.31 2.37e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs1008375 1.000 rs4698199 chr4:17656738 G/C cg15017067 chr4:17643749 FAM184B 0.34 5.86 0.3 1.08e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7089973 0.604 rs7895830 chr10:116625776 A/G cg23260525 chr10:116636907 FAM160B1 0.39 7.71 0.38 1.4e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs3820068 0.705 rs72645804 chr1:15868387 A/C cg17385448 chr1:15911702 AGMAT 0.4 6.55 0.33 2.1e-10 Systolic blood pressure; LIHC cis rs7116495 0.500 rs7123992 chr11:71746447 C/T cg26138937 chr11:71823887 C11orf51 -0.69 -6.98 -0.35 1.5e-11 Severe influenza A (H1N1) infection; LIHC cis rs1144333 0.655 rs76416835 chr1:76341511 G/T cg10523679 chr1:76189770 ACADM 0.45 5.96 0.31 6.18e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7618501 1.000 rs7372730 chr3:49790682 C/G cg21467203 chr3:49911342 NA 0.39 6.63 0.34 1.28e-10 Intelligence (multi-trait analysis); LIHC cis rs9394841 0.667 rs9367112 chr6:41769920 T/C cg17623882 chr6:41773611 USP49 -0.44 -5.87 -0.3 1.04e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs1055129 0.537 rs10852766 chr17:73951864 T/C cg14829360 chr17:73884958 NA 0.39 6.59 0.34 1.67e-10 White matter hyperintensity burden; LIHC cis rs12464559 0.522 rs4664498 chr2:152575417 A/G cg01189475 chr2:152685088 ARL5A 0.7 8.87 0.43 4.05e-17 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs11105298 0.786 rs10777186 chr12:89921277 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.3 -0.37 2.09e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2637266 0.714 rs7895605 chr10:78454207 G/A cg18941641 chr10:78392320 NA 0.27 5.87 0.3 1.02e-8 Pulmonary function; LIHC cis rs3862030 0.533 rs715440 chr10:104258095 A/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.51 -7.76 -0.39 1.02e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs2297440 0.527 rs4809318 chr20:62264760 G/A cg16989086 chr20:62203971 PRIC285 0.57 8.2 0.41 5.04e-15 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC cis rs7091068 0.671 rs514120 chr10:95404400 G/A cg20715218 chr10:95462985 C10orf4 -0.63 -6.91 -0.35 2.37e-11 Urinary tract infection frequency; LIHC trans rs9929218 1.000 rs12596061 chr16:68807828 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.61 -0.42 2.81e-16 Colorectal cancer; LIHC cis rs9921222 0.500 rs11648673 chr16:377794 G/A cg00101154 chr16:420108 MRPL28 -0.6 -8.26 -0.41 3.18e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs1008375 0.966 rs6832962 chr4:17652133 T/C cg16339924 chr4:17578868 LAP3 0.52 6.86 0.35 3.25e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs7116495 0.867 rs601865 chr11:71581938 G/A cg26138937 chr11:71823887 C11orf51 0.7 6.86 0.35 3.3e-11 Severe influenza A (H1N1) infection; LIHC cis rs10078 0.571 rs2671890 chr5:456457 A/G cg07599136 chr5:415885 AHRR 0.79 12.86 0.57 3.74e-31 Fat distribution (HIV); LIHC cis rs763121 0.853 rs10135 chr22:39082174 C/T cg21395723 chr22:39101663 GTPBP1 -0.38 -6.56 -0.33 1.99e-10 Menopause (age at onset); LIHC cis rs7927592 0.956 rs10896337 chr11:68284236 T/C cg20283391 chr11:68216788 NA -0.51 -7.6 -0.38 2.86e-13 Total body bone mineral density; LIHC trans rs911555 0.723 rs7144010 chr14:103869869 G/A cg17675199 chr6:35436792 RPL10A -0.4 -8.33 -0.41 1.98e-15 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg02782426 chr3:40428986 ENTPD3 0.34 6.36 0.33 6.32e-10 Renal cell carcinoma; LIHC cis rs151227923 1 rs151227923 chr7:155106564 C/T cg14927855 chr7:155151427 NA 0.35 6.77 0.34 5.68e-11 Stem cell growth factor beta levels; LIHC cis rs1868673 0.503 rs73169812 chr3:150242749 A/T cg10752315 chr3:150238463 NA 0.3 5.92 0.3 7.73e-9 Waist circumference; LIHC cis rs9359856 0.564 rs6914142 chr6:90398903 C/T cg13799429 chr6:90582589 CASP8AP2 -0.68 -6.33 -0.32 7.79e-10 Bipolar disorder; LIHC cis rs9858542 0.953 rs1801143 chr3:49570200 C/T cg03060546 chr3:49711283 APEH -0.47 -6.56 -0.33 1.94e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4908768 0.906 rs12410336 chr1:8623664 A/G cg25722041 chr1:8623473 RERE 0.43 6.13 0.31 2.45e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg21724239 chr8:58056113 NA 0.6 7.61 0.38 2.62e-13 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.19 -0.32 1.73e-9 Total body bone mineral density; LIHC trans rs13267838 1.000 rs13267838 chr8:25196710 G/T cg24998791 chr8:10454100 NA 0.48 6.11 0.31 2.74e-9 Glucose homeostasis traits; LIHC cis rs7208859 0.623 rs56163556 chr17:29101868 G/C cg14067834 chr17:29058358 SUZ12P 0.71 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7647973 0.626 rs2329021 chr3:49679072 G/A cg03060546 chr3:49711283 APEH 0.61 7.03 0.36 1.09e-11 Menarche (age at onset); LIHC trans rs35110281 0.807 rs2838328 chr21:45023234 G/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.63 0.34 1.3e-10 Mean corpuscular volume; LIHC cis rs7917772 0.582 rs7907760 chr10:104345197 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs61931739 0.517 rs1486882 chr12:34025896 A/G cg26384229 chr12:38710491 ALG10B 0.51 7.03 0.36 1.13e-11 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23628684 chr21:30446052 CCT8 0.52 7.54 0.38 4.28e-13 Pancreatic cancer; LIHC cis rs1046896 1.000 rs1046896 chr17:80685533 A/G cg00809820 chr17:80708513 TBCD;FN3K -0.34 -6.0 -0.31 4.95e-9 Glycated hemoglobin levels; LIHC cis rs6586163 1.000 rs6586164 chr10:90752031 T/A cg03111039 chr10:90751583 FAS;ACTA2 -0.57 -8.24 -0.41 3.65e-15 Chronic lymphocytic leukemia; LIHC cis rs7100689 0.555 rs1934146 chr10:82062121 C/A cg01528321 chr10:82214614 TSPAN14 0.83 11.06 0.51 1.62e-24 Post bronchodilator FEV1; LIHC cis rs7098414 0.511 rs10887826 chr10:82151380 C/T cg00277334 chr10:82204260 NA -0.6 -9.84 -0.47 2.81e-20 Post bronchodilator FEV1; LIHC cis rs4819052 1.000 rs13053002 chr21:46677854 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.72 9.92 0.47 1.45e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2839627 0.598 rs2246573 chr21:44253016 C/T cg18192155 chr21:44258298 NA -0.39 -5.9 -0.3 8.61e-9 Information processing speed; LIHC cis rs17685 0.712 rs1859792 chr7:75789264 T/C cg16684958 chr7:75615977 POR 0.39 6.39 0.33 5.41e-10 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06676920 chr19:13873854 CCDC130;MRI1 0.42 6.57 0.33 1.86e-10 Pancreatic cancer; LIHC cis rs919433 0.617 rs10931793 chr2:198577585 G/A cg00792783 chr2:198669748 PLCL1 -0.44 -6.43 -0.33 4.4e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs668210 0.894 rs1786171 chr11:65769809 G/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 6.82 0.35 4.1e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs7937682 0.632 rs57414412 chr11:111769431 G/A cg09085632 chr11:111637200 PPP2R1B 0.92 12.98 0.57 1.38e-31 Primary sclerosing cholangitis; LIHC cis rs4819052 0.851 rs2838849 chr21:46671027 A/G cg11663144 chr21:46675770 NA -0.32 -5.95 -0.31 6.7e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4780401 0.609 rs8047190 chr16:11807097 T/C cg01061890 chr16:11836724 TXNDC11 -0.65 -10.52 -0.49 1.32e-22 Rheumatoid arthritis; LIHC cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg24642844 chr7:1081250 C7orf50 -0.63 -6.33 -0.32 7.77e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17106184 1.000 rs12058681 chr1:51346663 A/T cg07174182 chr1:51127561 FAF1 -0.62 -6.51 -0.33 2.6200000000000003e-10 Type 2 diabetes; LIHC cis rs911119 0.908 rs12624424 chr20:23601878 C/T cg16589663 chr20:23618590 CST3 0.78 8.01 0.4 1.84e-14 Chronic kidney disease; LIHC cis rs10197940 0.710 rs4500942 chr2:152334580 A/G cg06191203 chr2:152266755 RIF1 -0.54 -9.74 -0.47 6.24e-20 Lung cancer; LIHC cis rs1577917 0.696 rs2842603 chr6:86336337 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.24 -0.32 1.27e-9 Response to antipsychotic treatment; LIHC cis rs5769765 1.000 rs910800 chr22:50278642 C/T cg02269571 chr22:50332266 NA 0.61 8.64 0.42 2.24e-16 Schizophrenia; LIHC cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg27170947 chr2:26402098 FAM59B 0.67 8.4 0.41 1.18e-15 Gut microbiome composition (summer); LIHC cis rs6461049 0.638 rs3778994 chr7:2175855 G/T cg04267008 chr7:1944627 MAD1L1 -0.41 -6.43 -0.33 4.34e-10 Schizophrenia; LIHC cis rs7208859 0.725 rs7342938 chr17:29189830 A/G cg13385521 chr17:29058706 SUZ12P 0.75 7.63 0.38 2.35e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg18404041 chr3:52824283 ITIH1 -0.49 -8.07 -0.4 1.21e-14 Electroencephalogram traits; LIHC cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg13047869 chr3:10149882 C3orf24 0.55 6.93 0.35 2.08e-11 Alzheimer's disease; LIHC cis rs10540 0.908 rs1044707 chr11:491334 G/T cg03352830 chr11:487213 PTDSS2 -0.7 -6.23 -0.32 1.36e-9 Body mass index; LIHC cis rs4820539 0.802 rs5759587 chr22:23441515 C/G cg14186256 chr22:23484241 RTDR1 0.84 15.3 0.64 1.32e-40 Bone mineral density; LIHC cis rs7666738 0.530 rs2865992 chr4:99067181 A/T cg05340658 chr4:99064831 C4orf37 0.4 6.16 0.32 2.06e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs904251 0.523 rs2776871 chr6:37481759 A/G cg25019722 chr6:37503610 NA -0.32 -5.73 -0.3 2.19e-8 Cognitive performance; LIHC cis rs600806 0.778 rs891380 chr1:110003286 T/G cg11161837 chr1:110010384 SYPL2 0.45 6.04 0.31 4.1e-9 Intelligence (multi-trait analysis); LIHC cis rs6466055 0.777 rs10487150 chr7:104797450 A/C cg04380332 chr7:105027541 SRPK2 -0.35 -6.51 -0.33 2.6200000000000003e-10 Schizophrenia; LIHC cis rs12464559 0.522 rs13016166 chr2:152624144 G/A cg01189475 chr2:152685088 ARL5A 0.72 9.16 0.44 4.95e-18 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs6582630 0.519 rs12819814 chr12:38332568 G/C cg26384229 chr12:38710491 ALG10B 0.57 7.78 0.39 8.78e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs34779708 0.733 rs11597184 chr10:35397396 G/A cg03585969 chr10:35415529 CREM 0.87 13.1 0.58 4.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg04082016 chr2:20871401 NA -0.42 -7.46 -0.37 7.29e-13 Abdominal aortic aneurysm; LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.71 -0.34 7.93e-11 Lymphocyte counts; LIHC cis rs4718428 0.705 rs13227468 chr7:66433563 T/C cg12165864 chr7:66369176 NA -0.48 -6.85 -0.35 3.45e-11 Corneal structure; LIHC cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg23031969 chr7:5014415 RNF216L -0.43 -6.04 -0.31 4.09e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07012231 chr7:47384322 TNS3 -0.38 -6.05 -0.31 3.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17001868 0.527 rs73167009 chr22:40734249 T/C cg07138101 chr22:40742427 ADSL 0.54 6.27 0.32 1.11e-9 Mammographic density (dense area); LIHC cis rs4773330 1.000 rs831169 chr13:111797920 G/A cg26911804 chr13:111806221 ARHGEF7 -0.62 -6.08 -0.31 3.3e-9 Bilirubin levels; LIHC cis rs1443512 0.755 rs1373160 chr12:54340383 A/G cg17410650 chr12:54324560 NA -0.38 -6.82 -0.35 4.06e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs35110281 0.744 rs230644 chr21:44917183 C/T cg21573476 chr21:45109991 RRP1B 0.51 9.22 0.45 3.23e-18 Mean corpuscular volume; LIHC cis rs7258465 0.896 rs8103660 chr19:18566395 T/C cg10790698 chr19:18539756 SSBP4 -0.35 -7.29 -0.37 2.1e-12 Breast cancer; LIHC cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg13395646 chr4:1353034 KIAA1530 -0.41 -6.52 -0.33 2.49e-10 Obesity-related traits; LIHC cis rs3849570 1.000 rs3849570 chr3:81792112 C/A cg07356753 chr3:81810745 GBE1 -0.64 -10.66 -0.5 4.28e-23 Waist circumference;Body mass index; LIHC cis rs8062405 0.755 rs62034358 chr16:28587597 G/T cg07451762 chr16:28383216 NA 0.39 6.88 0.35 2.88e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs5758659 0.935 rs134879 chr22:42664201 A/C cg19513890 chr22:42538836 CYP2D7P1 -0.38 -7.39 -0.37 1.14e-12 Cognitive function; LIHC cis rs6542838 0.704 rs12474283 chr2:99527310 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.29 -0.32 9.98e-10 Fear of minor pain; LIHC cis rs548181 0.545 rs4486648 chr11:125610589 T/A cg03464685 chr11:125439445 EI24 -0.83 -9.15 -0.44 5.25e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7762018 0.655 rs2184194 chr6:170148394 C/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.77 0.34 5.71e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6964587 0.692 rs2027950 chr7:91863700 C/G cg17063962 chr7:91808500 NA -0.68 -12.39 -0.56 2.28e-29 Breast cancer; LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg07133347 chr1:107600762 PRMT6 0.46 6.8 0.35 4.71e-11 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs783540 0.935 rs2278355 chr15:83331155 C/T cg18393722 chr15:85113863 UBE2QP1 0.38 6.44 0.33 4.04e-10 Schizophrenia; LIHC cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg20607798 chr8:58055168 NA 0.7 8.27 0.41 3.06e-15 Developmental language disorder (linguistic errors); LIHC cis rs6840360 0.806 rs13149588 chr4:152717757 C/T cg22705602 chr4:152727874 NA 0.33 6.87 0.35 3.09e-11 Intelligence (multi-trait analysis); LIHC cis rs780096 0.587 rs10205219 chr2:27568565 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.39 -6.0 -0.31 4.96e-9 Total body bone mineral density; LIHC cis rs12497850 0.931 rs4072859 chr3:49032205 G/C cg06212747 chr3:49208901 KLHDC8B 0.56 6.97 0.35 1.64e-11 Parkinson's disease; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg01696603 chr6:125623444 HDDC2 0.44 6.65 0.34 1.19e-10 Electroencephalogram traits; LIHC cis rs12602486 1.000 rs12601855 chr17:42224023 A/G cg08193365 chr17:42277699 NA 1.08 7.74 0.39 1.12e-13 Glycated hemoglobin levels; LIHC cis rs6088590 1.000 rs6087623 chr20:33317662 C/G cg24642439 chr20:33292090 TP53INP2 0.81 11.72 0.54 6.48e-27 Coronary artery disease; LIHC cis rs3768617 0.510 rs3768616 chr1:183103551 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.49e-22 Fuchs's corneal dystrophy; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg05315670 chr11:64037304 BAD -0.39 -6.28 -0.32 1.04e-9 Immature fraction of reticulocytes; LIHC cis rs6594499 0.872 rs6594498 chr5:110458351 G/A cg04022379 chr5:110408740 TSLP 0.49 8.11 0.4 9.18e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6466055 0.932 rs6466056 chr7:104929267 T/C cg04380332 chr7:105027541 SRPK2 0.34 6.4 0.33 5.02e-10 Schizophrenia; LIHC cis rs1008375 1.000 rs3815414 chr4:17606659 A/G cg02297831 chr4:17616191 MED28 -0.49 -7.52 -0.38 4.88e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.85 0.3 1.12e-8 Menopause (age at onset); LIHC cis rs2153535 0.580 rs1119691 chr6:8460452 C/T cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.28e-27 Motion sickness; LIHC cis rs7662987 0.517 rs1154410 chr4:100006645 A/G cg13256891 chr4:100009986 ADH5 0.56 5.85 0.3 1.12e-8 Smoking initiation; LIHC trans rs6489882 0.867 rs4767031 chr12:113362751 C/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6.08e-10 Chronic lymphocytic leukemia; LIHC cis rs1593 0.734 rs6815076 chr4:187224558 G/C cg14349977 chr4:187219430 NA 0.5 7.63 0.38 2.36e-13 Activated partial thromboplastin time; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg19941170 chr5:172067912 NEURL1B 0.41 6.11 0.31 2.7e-9 Migraine with aura; LIHC cis rs7914558 0.646 rs12768205 chr10:104647849 C/T cg15744005 chr10:104629667 AS3MT -0.35 -7.34 -0.37 1.54e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs864537 0.646 rs1723018 chr1:167433420 A/G cg22356347 chr1:167427500 CD247 -0.33 -5.74 -0.3 2.12e-8 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs875971 1.000 rs6460296 chr7:65895139 C/T cg18876405 chr7:65276391 NA 0.38 6.86 0.35 3.2e-11 Aortic root size; LIHC cis rs4407350 0.870 rs2213373 chr22:44911669 C/T cg11695653 chr22:44894386 LDOC1L -0.36 -6.06 -0.31 3.69e-9 Intelligence (multi-trait analysis); LIHC cis rs55702914 1.000 rs56234206 chr2:198215995 T/A cg10820045 chr2:198174542 NA 0.38 5.8 0.3 1.51e-8 Major depression and alcohol dependence; LIHC cis rs1018836 0.892 rs4735210 chr8:91549399 G/T cg16814680 chr8:91681699 NA -0.59 -9.67 -0.46 1.07e-19 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7412746 0.611 rs3768018 chr1:150723747 T/C cg17724175 chr1:150552817 MCL1 0.46 8.92 0.43 2.8e-17 Melanoma; LIHC cis rs7208859 0.623 rs9911784 chr17:29124580 A/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs10605167 1 rs10605167 chr11:94828467 TCTC/T cg22167515 chr1:91192466 NA 0.39 6.37 0.33 5.94e-10 Mean platelet volume; LIHC cis rs7224737 1.000 rs731152 chr17:40279680 G/A cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs4700695 0.841 rs706679 chr5:65317181 A/G cg21114390 chr5:65439923 SFRS12 -0.44 -5.75 -0.3 1.96e-8 Facial morphology (factor 19); LIHC cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.68 0.38 1.72e-13 Bipolar disorder; LIHC cis rs9534288 0.797 rs2148414 chr13:46582368 G/T cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs3814231 0.531 rs11196446 chr10:115471016 A/C cg24846397 chr10:115438155 CASP7 -0.42 -7.18 -0.36 4.42e-12 Vitiligo; LIHC cis rs1144333 0.579 rs35591768 chr1:76308257 C/T cg03433033 chr1:76189801 ACADM 0.46 7.18 0.36 4.43e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs4319547 0.656 rs7135419 chr12:122911861 T/A cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.55 -0.38 3.9e-13 Body mass index; LIHC cis rs7223966 1.000 rs8068603 chr17:61755211 T/A cg05941027 chr17:61774174 LIMD2 0.3 5.97 0.31 5.91e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs12478296 0.591 rs12719765 chr2:242997202 C/G cg06360820 chr2:242988706 NA -0.76 -11.57 -0.53 2.32e-26 Obesity-related traits; LIHC cis rs7662987 0.517 rs2602878 chr4:100039953 T/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs6665290 0.935 rs1929863 chr1:227195728 C/T cg10327440 chr1:227177885 CDC42BPA -1.19 -26.25 -0.82 5.98e-84 Myeloid white cell count; LIHC cis rs4919694 1.000 rs77318450 chr10:104733098 A/G cg04362960 chr10:104952993 NT5C2 1.06 7.65 0.38 2.03e-13 Arsenic metabolism; LIHC cis rs8062405 0.690 rs62034351 chr16:28565489 G/A cg07451762 chr16:28383216 NA 0.39 6.84 0.35 3.64e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg26338869 chr17:61819248 STRADA 0.52 6.89 0.35 2.77e-11 Height; LIHC cis rs79387448 0.745 rs6749440 chr2:103101846 C/T cg09003973 chr2:102972529 NA 0.81 7.11 0.36 6.95e-12 Gut microbiota (bacterial taxa); LIHC cis rs9367716 0.912 rs9382695 chr6:57110054 G/T cg03371099 chr6:57305889 PRIM2 -0.35 -5.72 -0.3 2.37e-8 Coronary artery disease; LIHC cis rs7107174 0.748 rs7105835 chr11:78075725 T/C cg02023728 chr11:77925099 USP35 0.41 7.7 0.38 1.45e-13 Testicular germ cell tumor; LIHC cis rs12079745 0.590 rs80215043 chr1:169193763 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.18 -0.32 1.81e-9 QT interval; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14473243 chr5:137514312 BRD8;KIF20A 0.49 6.41 0.33 4.88e-10 Lung function (FEV1/FVC); LIHC cis rs17253792 0.822 rs28478195 chr14:56047851 G/A cg24579896 chr14:56047964 C14orf33;KTN1 0.7 5.82 0.3 1.38e-8 Putamen volume; LIHC cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg25072359 chr17:41440525 NA 0.37 5.86 0.3 1.07e-8 Menopause (age at onset); LIHC cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.36 0.45 1.11e-18 Bipolar disorder; LIHC cis rs7100689 0.646 rs1953972 chr10:82145666 A/G cg01528321 chr10:82214614 TSPAN14 0.85 12.01 0.54 5.59e-28 Post bronchodilator FEV1; LIHC cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg18252515 chr7:66147081 NA 1.29 16.89 0.67 5.55e-47 Diabetic kidney disease; LIHC cis rs1419980 0.673 rs4883421 chr12:7774028 A/G cg25828445 chr12:7781288 NA 0.4 6.23 0.32 1.38e-9 HDL cholesterol levels; LIHC cis rs7945718 0.563 rs4525215 chr11:12664830 T/C cg25843174 chr11:12811716 TEAD1 0.31 6.96 0.35 1.76e-11 Educational attainment (years of education); LIHC cis rs514406 0.792 rs481440 chr1:53344976 C/T cg27535305 chr1:53392650 SCP2 -0.34 -6.27 -0.32 1.12e-9 Monocyte count; LIHC cis rs655641 1.000 rs2509609 chr11:85779162 C/G cg09030501 chr11:85779252 PICALM -0.51 -6.01 -0.31 4.83e-9 Platelet count; LIHC cis rs10911232 0.542 rs12128323 chr1:183050087 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.91e-23 Hypertriglyceridemia; LIHC cis rs9303401 0.703 rs8077052 chr17:57208921 T/G cg12560992 chr17:57184187 TRIM37 0.56 7.72 0.39 1.3e-13 Cognitive test performance; LIHC cis rs6598955 0.670 rs7522905 chr1:26609259 C/T cg00852783 chr1:26633632 UBXN11 0.51 8.56 0.42 4e-16 Obesity-related traits; LIHC cis rs2070488 1.000 rs2276540 chr3:38512507 G/A cg24069376 chr3:38537580 EXOG 0.42 7.76 0.39 9.78e-14 Electrocardiographic conduction measures; LIHC cis rs8062405 0.723 rs35175818 chr16:28608746 A/C cg07382826 chr16:28625726 SULT1A1 0.52 7.88 0.39 4.32e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs763121 0.853 rs2281021 chr22:39064667 T/C cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs6952808 0.929 rs4721217 chr7:1973579 C/T cg04267008 chr7:1944627 MAD1L1 -0.67 -10.7 -0.5 3e-23 Bipolar disorder and schizophrenia; LIHC cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg20887711 chr4:1340912 KIAA1530 0.49 7.51 0.38 5.16e-13 Obesity-related traits; LIHC cis rs6429082 0.967 rs704710 chr1:235621026 A/G cg26050004 chr1:235667680 B3GALNT2 0.38 6.19 0.32 1.74e-9 Adiposity; LIHC cis rs910316 0.967 rs175451 chr14:75589729 C/T cg11812906 chr14:75593930 NEK9 -0.77 -15.37 -0.64 6.82e-41 Height; LIHC cis rs12477438 0.765 rs17708262 chr2:99696313 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.51 -0.38 5.35e-13 Chronic sinus infection; LIHC cis rs4722166 0.695 rs7787893 chr7:22774437 A/G cg05472934 chr7:22766657 IL6 0.46 7.37 0.37 1.27e-12 Lung cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23151374 chr4:164415611 C4orf43 0.45 6.88 0.35 2.9100000000000002e-11 Pancreatic cancer; LIHC cis rs10792665 0.686 rs1904428 chr11:82718252 A/C cg24227371 chr11:82718527 RAB30 0.39 9.53 0.46 2.98e-19 Obesity-related traits; LIHC trans rs1864585 0.520 rs73208793 chr8:10680785 T/C cg20373634 chr10:103911536 NOLC1 -0.47 -6.19 -0.32 1.76e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs244731 0.959 rs10037110 chr5:176658066 A/T cg16006841 chr5:176797999 RGS14 -0.61 -5.97 -0.31 5.9e-9 Urate levels in lean individuals; LIHC cis rs3008870 1.000 rs2985822 chr1:67404910 T/G cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC trans rs4906332 1.000 rs11625172 chr14:103944912 G/A cg17675199 chr6:35436792 RPL10A 0.35 6.86 0.35 3.26e-11 Coronary artery disease; LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg04234412 chr22:24373322 LOC391322 -0.69 -10.27 -0.49 9.86e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11711311 0.868 rs13091621 chr3:113481977 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.28 -0.37 2.29e-12 IgG glycosylation; LIHC cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg09913183 chr17:42254507 C17orf65;ASB16 0.79 12.07 0.55 3.43e-28 Total body bone mineral density; LIHC cis rs7917772 0.582 rs10786689 chr10:104356359 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4665809 1.000 rs6546736 chr2:26293878 C/T cg27170947 chr2:26402098 FAM59B 0.64 7.89 0.39 4.15e-14 Gut microbiome composition (summer); LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg07677032 chr17:61819896 STRADA 0.43 6.07 0.31 3.49e-9 Prudent dietary pattern; LIHC cis rs807669 0.807 rs712948 chr22:19206499 A/G cg02655711 chr22:19163373 SLC25A1 0.72 10.16 0.48 2.22e-21 Metabolite levels; LIHC cis rs10870270 0.957 rs3753008 chr10:133785129 A/C cg26149184 chr10:133730230 NA 0.46 7.49 0.38 5.99e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs599083 0.569 rs685095 chr11:68170376 C/T cg01657329 chr11:68192670 LRP5 0.57 7.59 0.38 3.02e-13 Bone mineral density (spine); LIHC cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg02951883 chr7:2050386 MAD1L1 -0.67 -10.97 -0.51 3.47e-24 Bipolar disorder and schizophrenia; LIHC trans rs116095464 0.558 rs55838121 chr5:266890 G/A cg00938859 chr5:1591904 SDHAP3 0.56 6.81 0.35 4.43e-11 Breast cancer; LIHC cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg16325326 chr1:53192061 ZYG11B -0.5 -8.78 -0.43 8.15e-17 Monocyte count; LIHC cis rs6840360 0.593 rs4696287 chr4:152606723 C/T cg22705602 chr4:152727874 NA -0.34 -7.05 -0.36 9.96e-12 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.966 rs4934540 chr10:35474699 T/C cg03585969 chr10:35415529 CREM 0.86 13.02 0.58 9.5e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg02290350 chr8:58132656 NA 0.5 10.64 0.5 5.15e-23 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.608 rs17361504 chr15:76601871 A/G cg22467129 chr15:76604101 ETFA -0.37 -6.11 -0.31 2.68e-9 Blood metabolite levels; LIHC cis rs2070488 1.000 rs762317 chr3:38497659 A/G cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC trans rs61931739 0.534 rs28548399 chr12:34188151 G/A cg26384229 chr12:38710491 ALG10B 0.6 7.67 0.38 1.83e-13 Morning vs. evening chronotype; LIHC cis rs7582180 0.591 rs11674569 chr2:101010860 G/A cg14675211 chr2:100938903 LONRF2 0.54 8.25 0.41 3.54e-15 Intelligence (multi-trait analysis); LIHC cis rs13343954 0.518 rs7252086 chr19:33534929 T/C cg27124370 chr19:33622961 WDR88 0.52 7.79 0.39 8.16e-14 Colorectal cancer; LIHC cis rs8114671 0.836 rs3746432 chr20:33592763 C/T cg07148914 chr20:33460835 GGT7 -0.56 -8.57 -0.42 3.55e-16 Height; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC trans rs9929218 1.000 rs9282650 chr16:68809640 T/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg04234412 chr22:24373322 LOC391322 -0.68 -9.97 -0.47 1.03e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs919433 0.889 rs788004 chr2:198219032 C/T cg03934865 chr2:198174659 NA 0.55 8.81 0.43 6.23e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3749237 0.615 rs6792911 chr3:49429856 C/T cg02487422 chr3:49467188 NICN1 0.39 5.9 0.3 8.72e-9 Resting heart rate; LIHC cis rs3770081 0.590 rs34522092 chr2:86208305 G/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.78 -8.2 -0.41 4.82e-15 Facial emotion recognition (sad faces); LIHC cis rs2242116 0.796 rs2290546 chr3:46965197 C/G cg27129171 chr3:47204927 SETD2 0.55 8.81 0.43 6.22e-17 Birth weight; LIHC cis rs5769707 0.521 rs7285764 chr22:50058561 T/C cg07959070 chr22:50026188 C22orf34 -0.3 -7.22 -0.36 3.33e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9910055 0.530 rs11652651 chr17:42302907 A/G cg09913183 chr17:42254507 C17orf65;ASB16 -0.65 -9.5 -0.46 3.83e-19 Total body bone mineral density; LIHC cis rs7572733 0.534 rs700688 chr2:198723833 A/G cg10820045 chr2:198174542 NA -0.5 -7.63 -0.38 2.36e-13 Dermatomyositis; LIHC cis rs1499280 0.736 rs7719930 chr5:52105307 T/C cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs1401999 1.000 rs2872249 chr3:183636273 T/A cg01324343 chr3:183735012 ABCC5 0.73 11.96 0.54 8.84e-28 Anterior chamber depth; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11453347 chr10:127512288 UROS;BCCIP 0.46 6.72 0.34 7.45e-11 Cognitive function; LIHC cis rs9309473 0.861 rs6546856 chr2:73837751 T/C cg20560298 chr2:73613845 ALMS1 -0.55 -6.97 -0.35 1.65e-11 Metabolite levels; LIHC cis rs1953600 0.715 rs1079242 chr10:81917708 C/T cg04850286 chr10:81895943 PLAC9 0.32 5.92 0.3 7.74e-9 Sarcoidosis; LIHC cis rs4843747 0.749 rs12102841 chr16:88072574 C/G cg00677901 chr16:88017247 BANP -0.57 -8.78 -0.43 7.93e-17 Menopause (age at onset); LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg02782426 chr3:40428986 ENTPD3 -0.35 -6.46 -0.33 3.52e-10 Renal cell carcinoma; LIHC trans rs9500256 0.903 rs726783 chr6:58332861 A/C cg03371099 chr6:57305889 PRIM2 -0.36 -6.38 -0.33 5.9e-10 Eosinophilic esophagitis (pediatric); LIHC cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg11890956 chr21:40555474 PSMG1 1.07 15.36 0.64 7.19e-41 Cognitive function; LIHC cis rs28530618 0.603 rs11697988 chr20:31248176 C/G cg13636640 chr20:31349939 DNMT3B -0.42 -5.85 -0.3 1.17e-8 Birth weight; LIHC cis rs1055129 0.655 rs7223416 chr17:73836162 C/G cg10935138 chr17:73851978 WBP2 0.44 6.98 0.35 1.56e-11 White matter hyperintensity burden; LIHC cis rs10779751 0.770 rs10864490 chr1:11236410 A/C cg08854313 chr1:11322531 MTOR 0.83 12.42 0.56 1.79e-29 Body mass index; LIHC cis rs6952808 0.771 rs4719336 chr7:1916397 T/C cg21782813 chr7:2030301 MAD1L1 0.43 7.1 0.36 7.17e-12 Bipolar disorder and schizophrenia; LIHC cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg19318889 chr4:1322082 MAEA 0.43 6.21 0.32 1.57e-9 Obesity-related traits; LIHC trans rs9926296 0.581 rs12598477 chr16:89902482 T/C cg13698153 chr12:118541722 VSIG10 0.61 6.34 0.32 7.37e-10 Vitiligo; LIHC cis rs10464366 0.746 rs17171537 chr7:39145647 C/T cg20302533 chr7:39170763 POU6F2 0.38 6.96 0.35 1.8e-11 IgG glycosylation; LIHC cis rs1552244 0.572 rs59074548 chr3:10164347 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs35110281 0.807 rs6518301 chr21:45016818 T/C cg04455712 chr21:45112962 RRP1B 0.45 7.72 0.39 1.29e-13 Mean corpuscular volume; LIHC cis rs1005277 0.522 rs11011343 chr10:38002698 A/G cg25427524 chr10:38739819 LOC399744 -0.62 -11.98 -0.54 7.28e-28 Extrinsic epigenetic age acceleration; LIHC cis rs7264396 0.563 rs7264869 chr20:34346502 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -7.81 -0.39 7.11e-14 Total cholesterol levels; LIHC cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg13012494 chr21:47604986 C21orf56 0.39 6.04 0.31 4.12e-9 Testicular germ cell tumor; LIHC cis rs2066819 1.000 rs77853814 chr12:56687572 G/T cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19437070 chr15:78442260 IDH3A -0.57 -7.4 -0.37 1.08e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7412746 0.658 rs72704682 chr1:150897677 A/T cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs854572 0.600 rs705382 chr7:94955221 C/G cg19678392 chr7:94953810 PON1 -0.53 -8.96 -0.44 2.15e-17 Paraoxonase activity; LIHC cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg16325326 chr1:53192061 ZYG11B -0.41 -6.98 -0.35 1.51e-11 Monocyte count; LIHC cis rs17125944 0.686 rs76673112 chr14:53366692 T/C cg00686598 chr14:53173677 PSMC6 0.9 9.72 0.47 7.27e-20 Alzheimer's disease (late onset); LIHC cis rs818427 0.964 rs459102 chr5:112228765 C/A cg07820702 chr5:112228657 REEP5 -0.37 -5.83 -0.3 1.28e-8 Total body bone mineral density; LIHC cis rs7772486 0.875 rs9322048 chr6:146400439 A/G cg23711669 chr6:146136114 FBXO30 0.56 9.78 0.47 4.35e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs57502260 0.573 rs11228295 chr11:68388588 C/G cg16797656 chr11:68205561 LRP5 0.42 6.15 0.32 2.21e-9 Total body bone mineral density (age 45-60); LIHC cis rs7312774 0.618 rs4964518 chr12:107466217 C/T cg16260113 chr12:107380972 MTERFD3 1.04 13.38 0.59 3.83e-33 Severe influenza A (H1N1) infection; LIHC cis rs4808199 0.895 rs7252888 chr19:19628037 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.42 5.93 0.31 7.59e-9 Nonalcoholic fatty liver disease; LIHC cis rs1059312 0.771 rs11059922 chr12:129290418 C/T cg09035930 chr12:129282057 SLC15A4 0.6 11.26 0.52 3.12e-25 Systemic lupus erythematosus; LIHC cis rs11098499 0.863 rs2306457 chr4:120472839 T/A cg09307838 chr4:120376055 NA 0.75 11.3 0.52 2.24e-25 Corneal astigmatism; LIHC cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 11.66 0.53 1.15e-26 Alzheimer's disease; LIHC cis rs4555082 0.874 rs11625098 chr14:105756891 A/G cg06808227 chr14:105710500 BRF1 -0.48 -5.9 -0.3 8.64e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs4555082 0.830 rs3803319 chr14:105752458 G/A cg06808227 chr14:105710500 BRF1 -0.57 -7.6 -0.38 2.89e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs7020830 0.867 rs55845273 chr9:37362219 C/T cg14294708 chr9:37120828 ZCCHC7 1.03 20.69 0.75 3.07e-62 Schizophrenia; LIHC cis rs9611565 0.512 rs139566 chr22:42199277 A/G cg03806693 chr22:41940476 POLR3H -0.97 -10.49 -0.49 1.69e-22 Vitiligo; LIHC cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.35 0.41 1.71e-15 Platelet count; LIHC cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg18357526 chr6:26021779 HIST1H4A -0.57 -7.05 -0.36 1e-11 Blood metabolite levels; LIHC trans rs1941687 0.509 rs7238029 chr18:31317755 A/G cg27147174 chr7:100797783 AP1S1 -0.46 -6.29 -0.32 9.54e-10 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs9790314 0.967 rs463928 chr3:161087734 A/T cg04691961 chr3:161091175 C3orf57 -0.45 -7.25 -0.36 2.81e-12 Morning vs. evening chronotype; LIHC cis rs11098499 0.739 rs9884728 chr4:120127079 C/T cg09307838 chr4:120376055 NA -0.49 -7.54 -0.38 4.38e-13 Corneal astigmatism; LIHC trans rs7618501 0.966 rs2246832 chr3:49881134 A/T cg21665057 chr3:196295764 WDR53;FBXO45 0.79 13.82 0.6 8.23e-35 Intelligence (multi-trait analysis); LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg04082016 chr2:20871401 NA 0.38 7.28 0.37 2.25e-12 Abdominal aortic aneurysm; LIHC cis rs1494950 1.000 rs9998291 chr4:15022277 A/G cg12377275 chr4:15005593 CPEB2 -0.85 -7.42 -0.37 9.57e-13 Political ideology; LIHC cis rs2404602 0.669 rs1875885 chr15:76638081 G/A cg23625390 chr15:77176239 SCAPER 0.37 6.0 0.31 5.07e-9 Blood metabolite levels; LIHC cis rs2361718 0.501 rs12944619 chr17:78144109 T/C cg09238746 chr17:78121135 EIF4A3 -0.87 -14.13 -0.61 4.98e-36 Yeast infection; LIHC cis rs7107174 1.000 rs10899457 chr11:78001163 T/A cg02023728 chr11:77925099 USP35 0.5 9.55 0.46 2.56e-19 Testicular germ cell tumor; LIHC cis rs2228479 0.850 rs11641552 chr16:89838700 C/A cg04013166 chr16:89971882 TCF25 0.53 6.64 0.34 1.23e-10 Skin colour saturation; LIHC cis rs2404602 0.647 rs11072618 chr15:77019342 A/G cg03037974 chr15:76606532 NA -0.6 -10.03 -0.48 6.11e-21 Blood metabolite levels; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05620814 chr16:74640948 GLG1 0.49 6.14 0.32 2.26e-9 Hepatitis; LIHC cis rs365132 0.875 rs353479 chr5:176372593 C/T cg16309518 chr5:176445507 NA -0.52 -9.87 -0.47 2.21e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs8180040 0.966 rs13064843 chr3:47415467 C/T cg27129171 chr3:47204927 SETD2 0.58 9.87 0.47 2.13e-20 Colorectal cancer; LIHC cis rs2832191 0.791 rs8134407 chr21:30476586 G/A cg08807101 chr21:30365312 RNF160 0.64 10.17 0.48 2.13e-21 Dental caries; LIHC cis rs6952808 0.756 rs12537348 chr7:1948172 C/G cg14004847 chr7:1930337 MAD1L1 -0.48 -6.81 -0.35 4.46e-11 Bipolar disorder and schizophrenia; LIHC cis rs11098499 0.954 rs71614438 chr4:120371252 G/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03053427 chr7:75649626 STYXL1 0.45 6.73 0.34 7.05e-11 Cognitive function; LIHC cis rs4665809 1.000 rs7588802 chr2:26277789 A/G cg04944784 chr2:26401820 FAM59B -0.67 -8.4 -0.41 1.24e-15 Gut microbiome composition (summer); LIHC cis rs28830936 1.000 rs17677199 chr15:41954613 C/G cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.74 -0.3 2.07e-8 Diastolic blood pressure; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.41 0.37 9.74e-13 Height; LIHC cis rs3015497 0.789 rs3015496 chr14:51114051 T/C cg09863266 chr14:51125203 SAV1 -0.42 -6.83 -0.35 3.79e-11 Mean platelet volume; LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg03874509 chr1:107600012 PRMT6 -0.77 -12.17 -0.55 1.47e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg16325326 chr1:53192061 ZYG11B -0.41 -6.94 -0.35 1.95e-11 Monocyte count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15203618 chr11:85646125 NA -0.4 -6.22 -0.32 1.44e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00365505 chr7:150066001 REPIN1 -0.48 -6.53 -0.33 2.34e-10 Pancreatic cancer; LIHC trans rs2749592 0.513 rs1208708 chr10:38085576 A/G cg04469686 chr1:162760199 HSD17B7 -0.41 -6.53 -0.33 2.38e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3806843 0.735 rs2563306 chr5:140070017 C/T cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs910316 0.726 rs12882664 chr14:75446778 C/T cg11812906 chr14:75593930 NEK9 0.73 13.53 0.59 1.05e-33 Height; LIHC cis rs7100689 0.577 rs4934038 chr10:82057334 C/A cg01528321 chr10:82214614 TSPAN14 0.88 11.95 0.54 9.25e-28 Post bronchodilator FEV1; LIHC cis rs778371 0.697 rs11893358 chr2:233636922 T/C cg08000102 chr2:233561755 GIGYF2 0.9 14.88 0.63 5.84e-39 Schizophrenia; LIHC cis rs6951245 1.000 rs11763020 chr7:1060288 C/T cg08132940 chr7:1081526 C7orf50 -0.74 -6.36 -0.33 6.5e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7917772 0.599 rs2863717 chr10:104519829 A/G cg22532475 chr10:104410764 TRIM8 0.37 6.39 0.33 5.3e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6964587 1.000 rs7781597 chr7:91588194 T/C cg17063962 chr7:91808500 NA 1.02 19.09 0.72 8.15e-56 Breast cancer; LIHC trans rs875971 0.545 rs73376394 chr7:65637681 C/T cg26939375 chr7:64535504 NA 0.39 6.15 0.32 2.12e-9 Aortic root size; LIHC cis rs919433 0.680 rs4685 chr2:198257795 C/T cg10820045 chr2:198174542 NA -0.54 -8.82 -0.43 6.04e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6456156 0.586 rs10946208 chr6:167459596 C/T cg23791538 chr6:167370224 RNASET2 -0.53 -8.46 -0.42 7.96e-16 Primary biliary cholangitis; LIHC cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.7 6.9 0.35 2.56e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs769267 0.895 rs2916074 chr19:19530270 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.97 0.4 2.38e-14 Tonsillectomy; LIHC cis rs769267 0.930 rs7256149 chr19:19566255 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.93 0.39 3.07e-14 Tonsillectomy; LIHC cis rs2832191 0.765 rs2832162 chr21:30461808 G/A cg08807101 chr21:30365312 RNF160 0.55 8.57 0.42 3.72e-16 Dental caries; LIHC cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg21448741 chr8:58168803 NA 0.36 5.91 0.3 8.43e-9 Developmental language disorder (linguistic errors); LIHC cis rs7542091 0.637 rs9429826 chr1:210052146 G/A cg22029157 chr1:209979665 IRF6 0.36 6.06 0.31 3.7e-9 Monobrow; LIHC cis rs370915 0.963 rs59452206 chr4:187816484 G/T cg12892747 chr4:187813459 NA -0.42 -6.54 -0.33 2.3e-10 Gout; LIHC cis rs11098499 0.863 rs3775844 chr4:120428033 G/A cg09307838 chr4:120376055 NA 0.77 11.99 0.54 7.12e-28 Corneal astigmatism; LIHC cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg27170947 chr2:26402098 FAM59B -0.65 -8.34 -0.41 1.83e-15 Gut microbiome composition (summer); LIHC cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.82 -12.95 -0.57 1.74e-31 Total body bone mineral density; LIHC cis rs6429082 0.755 rs291371 chr1:235693105 C/G cg26050004 chr1:235667680 B3GALNT2 0.42 6.86 0.35 3.16e-11 Adiposity; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.93 -0.31 7.3e-9 Total body bone mineral density; LIHC cis rs11018874 0.532 rs11018867 chr11:89862345 C/T cg04552319 chr11:89519481 NA -0.33 -5.72 -0.3 2.32e-8 White blood cell types; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg03874509 chr1:107600012 PRMT6 0.7 11.31 0.52 2.12e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs58688157 0.705 rs11539530 chr11:609353 G/A cg16486109 chr11:613632 IRF7 0.59 6.29 0.32 9.88e-10 Systemic lupus erythematosus; LIHC cis rs6815814 0.950 rs11722813 chr4:38810769 C/T cg06935464 chr4:38784597 TLR10 0.45 7.13 0.36 5.99e-12 Breast cancer; LIHC cis rs11785400 1.000 rs3735994 chr8:143742683 C/T cg10596483 chr8:143751796 JRK 0.51 8.32 0.41 2.06e-15 Schizophrenia; LIHC cis rs8013055 0.898 rs8004007 chr14:105971435 G/C cg19700328 chr14:106028568 NA -0.36 -7.73 -0.39 1.23e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs11792861 0.816 rs3763643 chr9:111695607 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 9.17 0.44 4.45e-18 Menarche (age at onset); LIHC cis rs7264396 0.563 rs2425100 chr20:34310115 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.76 -0.43 9.08e-17 Total cholesterol levels; LIHC cis rs56011263 0.687 rs4690188 chr4:703930 G/C cg20735989 chr4:730612 PCGF3 -0.67 -8.84 -0.43 5.17e-17 White blood cell count; LIHC cis rs1005277 0.579 rs2505198 chr10:38393183 A/C cg25427524 chr10:38739819 LOC399744 -0.68 -13.35 -0.59 5.14e-33 Extrinsic epigenetic age acceleration; LIHC cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg20887711 chr4:1340912 KIAA1530 0.8 12.08 0.55 3.18e-28 Longevity; LIHC cis rs13126513 0.510 rs10516445 chr4:100524679 C/G cg05468953 chr4:100565104 NA 0.35 7.5 0.38 5.41e-13 Metabolite levels (MHPG); LIHC cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg24549020 chr5:56110836 MAP3K1 0.5 6.2 0.32 1.63e-9 Initial pursuit acceleration; LIHC cis rs17685 0.712 rs10271413 chr7:75754858 G/A cg16684958 chr7:75615977 POR 0.51 8.54 0.42 4.54e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7903847 0.642 rs11189183 chr10:99144321 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2295359 0.892 rs72676058 chr1:67627681 C/A cg12940439 chr1:67600707 NA 0.39 6.98 0.35 1.54e-11 Psoriasis; LIHC cis rs6542838 0.704 rs13011428 chr2:99528305 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.82 -0.35 4.18e-11 Fear of minor pain; LIHC cis rs7264396 0.790 rs761825 chr20:34194054 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.52 -9.11 -0.44 7.22e-18 Total cholesterol levels; LIHC cis rs6960043 0.764 rs7798124 chr7:15055616 A/G cg19272540 chr7:15055459 NA -0.26 -6.93 -0.35 2.09e-11 Type 2 diabetes; LIHC cis rs7582180 0.629 rs6757754 chr2:100951273 C/T cg14675211 chr2:100938903 LONRF2 -0.53 -8.6 -0.42 2.94e-16 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg06238570 chr21:40685208 BRWD1 0.6 7.05 0.36 1e-11 Cognitive function; LIHC cis rs317689 0.581 rs315132 chr12:69761996 G/C cg20891283 chr12:69753455 YEATS4 0.83 16.41 0.66 5e-45 Response to diuretic therapy; LIHC cis rs2274273 0.837 rs10131913 chr14:55787420 A/G cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.37e-9 Protein biomarker; LIHC cis rs10463316 0.817 rs11167545 chr5:150778076 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -6.16 -0.32 2.08e-9 Metabolite levels (Pyroglutamine); LIHC cis rs7635838 0.892 rs7372723 chr3:11466511 G/A cg00170343 chr3:11313890 ATG7 0.43 6.77 0.34 5.46e-11 HDL cholesterol; LIHC cis rs35146811 0.771 rs1060544 chr7:99613476 C/T cg22906224 chr7:99728672 NA 0.45 6.41 0.33 4.71e-10 Coronary artery disease; LIHC trans rs6578985 0.828 rs12290802 chr11:2121754 G/A cg20230732 chr3:128721448 CCDC48 0.38 6.2 0.32 1.67e-9 Femoral neck bone geometry and menarche (age at onset); LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.01 21.96 0.76 2.7e-67 Height; LIHC cis rs2836974 0.583 rs8132993 chr21:40716410 T/C cg11890956 chr21:40555474 PSMG1 0.55 8.16 0.4 6.58e-15 Cognitive function; LIHC cis rs1200821 0.529 rs2505707 chr10:37801254 T/C cg00409905 chr10:38381863 ZNF37A -0.43 -6.74 -0.34 6.8e-11 Hemostatic factors and hematological phenotypes; LIHC cis rs7238033 0.663 rs11082467 chr18:43318644 A/G cg20610511 chr18:43302872 SLC14A1 0.39 6.5 0.33 2.87e-10 Bladder cancer; LIHC cis rs7131987 0.903 rs7302129 chr12:29415280 A/T cg05697976 chr12:29376483 FAR2 0.31 6.13 0.31 2.44e-9 QT interval; LIHC cis rs4474465 0.915 rs4944204 chr11:78222013 G/T cg02023728 chr11:77925099 USP35 -0.33 -5.84 -0.3 1.2e-8 Alzheimer's disease (survival time); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13327734 chr17:4634568 MED11 0.48 6.59 0.34 1.71e-10 Pancreatic cancer; LIHC cis rs6500602 0.727 rs2058811 chr16:4575162 C/T cg08645402 chr16:4508243 NA 0.45 8.37 0.41 1.45e-15 Schizophrenia; LIHC cis rs6723226 0.721 rs3769600 chr2:32616879 G/A cg02381751 chr2:32503542 YIPF4 -0.6 -9.1 -0.44 7.88e-18 Intelligence (multi-trait analysis); LIHC cis rs2245008 0.671 rs907036 chr16:83989850 A/T cg26931527 chr16:83979911 NA 0.48 6.15 0.32 2.19e-9 Pursuit maintenance gain; LIHC cis rs12458462 0.812 rs36073957 chr18:77488441 C/T cg11879182 chr18:77439856 CTDP1 0.83 13.38 0.59 4.01e-33 Monocyte count; LIHC cis rs6860806 0.507 rs274572 chr5:131710917 T/G cg24060327 chr5:131705240 SLC22A5 0.79 12.43 0.56 1.53e-29 Breast cancer; LIHC trans rs10411161 0.810 rs11667971 chr19:52407694 G/A cg22319618 chr22:45562946 NUP50 -0.61 -7.0 -0.35 1.35e-11 Breast cancer; LIHC cis rs79839061 0.610 rs3736089 chr4:870118 G/A cg07828340 chr4:882639 GAK 0.83 7.02 0.36 1.18e-11 Intelligence (multi-trait analysis); LIHC cis rs9952991 0.941 rs2847280 chr18:12779342 A/G cg23598886 chr18:12777645 NA 0.48 6.51 0.33 2.69e-10 Inflammatory skin disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17520314 chr17:79604207 NPLOC4 0.51 6.54 0.33 2.31e-10 Lung function (FEV1/FVC); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06269035 chr16:1663677 CRAMP1L -0.47 -6.7 -0.34 8.71e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs243505 0.660 rs1880358 chr7:148572504 C/T cg09806900 chr7:148480153 CUL1 0.43 6.26 0.32 1.15e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3096299 0.933 rs3096297 chr16:89453155 T/G cg08822215 chr16:89438651 ANKRD11 -0.45 -7.08 -0.36 8.05e-12 Multiple myeloma (IgH translocation); LIHC cis rs57590327 0.679 rs7639135 chr3:81608976 C/T cg07356753 chr3:81810745 GBE1 -0.48 -6.54 -0.33 2.25e-10 Extraversion; LIHC cis rs1552244 0.882 rs3732967 chr3:10015437 T/C cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs6951245 0.832 rs10266519 chr7:1142977 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.68 5.79 0.3 1.6e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08555112 chr17:48942811 TOB1 0.49 7.72 0.39 1.33e-13 Cognitive function; LIHC cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg22633049 chr21:46681294 NA -0.37 -6.51 -0.33 2.61e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg24531977 chr5:56204891 C5orf35 -0.69 -9.92 -0.47 1.47e-20 Initial pursuit acceleration; LIHC cis rs9790314 0.690 rs6441354 chr3:160826404 A/G cg03342759 chr3:160939853 NMD3 -0.7 -10.07 -0.48 4.8e-21 Morning vs. evening chronotype; LIHC cis rs6089584 0.830 rs6089309 chr20:60585687 T/C cg13770153 chr20:60521292 NA -0.32 -6.14 -0.32 2.28e-9 Body mass index; LIHC cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg02951883 chr7:2050386 MAD1L1 -0.76 -13.05 -0.58 7.55e-32 Bipolar disorder and schizophrenia; LIHC cis rs1943345 0.830 rs571055 chr11:82898829 G/C cg07047830 chr11:82868014 PCF11 0.44 6.93 0.35 2.13e-11 Obesity-related traits; LIHC cis rs208520 1.000 rs208521 chr6:66953625 C/T cg07460842 chr6:66804631 NA -0.65 -6.86 -0.35 3.2e-11 Exhaled nitric oxide output; LIHC cis rs2836974 0.644 rs11088471 chr21:40699313 A/G cg11890956 chr21:40555474 PSMG1 -0.45 -7.2 -0.36 3.81e-12 Cognitive function; LIHC trans rs2579103 0.767 rs1347844 chr12:90663216 G/A cg00091569 chr3:40428383 ENTPD3 0.37 6.05 0.31 3.8e-9 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01130162 chr16:838502 CHTF18;RPUSD1 -0.41 -6.13 -0.31 2.38e-9 Cognitive function; LIHC cis rs4474465 1.000 rs4944200 chr11:78166930 C/A cg02023728 chr11:77925099 USP35 0.32 5.85 0.3 1.14e-8 Alzheimer's disease (survival time); LIHC cis rs9303401 0.659 rs1864754 chr17:56688789 G/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.9 -11.95 -0.54 1e-27 Cognitive test performance; LIHC cis rs12479064 0.724 rs2309618 chr2:99974473 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -8.63 -0.42 2.37e-16 Chronic sinus infection; LIHC cis rs1419980 0.730 rs11054870 chr12:7770803 A/C cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg08280861 chr8:58055591 NA 0.53 6.5 0.33 2.78e-10 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg00106254 chr7:1943704 MAD1L1 0.4 6.36 0.33 6.59e-10 Bipolar disorder and schizophrenia; LIHC cis rs55823223 0.564 rs4572466 chr17:73846314 A/C cg19302996 chr17:73780495 UNK -0.55 -6.8 -0.35 4.72e-11 Psoriasis; LIHC cis rs9534288 0.913 rs9534299 chr13:46625586 A/T cg15192986 chr13:46630673 CPB2 -0.58 -8.63 -0.42 2.29e-16 Blood protein levels; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg13152130 chr6:118910203 C6orf204 -0.65 -7.34 -0.37 1.61e-12 Diastolic blood pressure; LIHC cis rs6748734 0.948 rs9973334 chr2:241838142 A/G cg04034577 chr2:241836375 C2orf54 -0.49 -11.48 -0.53 5.09e-26 Urinary metabolites; LIHC trans rs561341 0.505 rs548298 chr17:30297494 C/A cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 8.04e-24 Hip circumference adjusted for BMI; LIHC cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg27297192 chr10:134578999 INPP5A 0.53 7.55 0.38 4e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs7131987 0.621 rs11050181 chr12:29467669 C/T cg12903224 chr12:29470962 FAR2 -0.42 -6.74 -0.34 6.88e-11 QT interval; LIHC cis rs35146811 0.883 rs4134903 chr7:99711040 G/A cg13334819 chr7:99746414 C7orf59 -0.6 -8.48 -0.42 6.68e-16 Coronary artery disease; LIHC cis rs2073300 0.609 rs79250740 chr20:23417165 G/A cg12062639 chr20:23401060 NAPB 1.04 13.43 0.59 2.56e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6867032 1.000 rs4074914 chr5:2020274 C/T cg26168224 chr5:2018326 NA 0.31 7.66 0.38 1.91e-13 Gut microbiome composition (winter); LIHC cis rs1559088 0.847 rs2287679 chr19:33600764 T/C cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1008375 0.686 rs34338142 chr4:17626174 T/A cg02297831 chr4:17616191 MED28 0.48 7.56 0.38 3.62e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7106204 0.748 rs12273426 chr11:24212058 T/C ch.11.24196551F chr11:24239977 NA 0.78 10.26 0.49 1.03e-21 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6582630 0.502 rs11520234 chr12:38255005 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Drug-induced liver injury (flucloxacillin); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11062956 chr16:2723328 NA -0.42 -6.25 -0.32 1.24e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg11070056 chr1:107600091 PRMT6 0.63 10.48 0.49 1.73e-22 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs1814175 0.817 rs4881623 chr11:49804991 C/T cg03929089 chr4:120376271 NA -0.9 -18.39 -0.71 5.32e-53 Height; LIHC cis rs12594515 1.000 rs6493169 chr15:45986994 A/G cg06207120 chr15:45996521 NA -0.32 -6.3 -0.32 9.36e-10 Waist circumference;Weight; LIHC cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg05590025 chr7:65112418 INTS4L2 0.6 6.43 0.33 4.2e-10 Diabetic kidney disease; LIHC cis rs918629 0.716 rs7700895 chr5:95273410 T/A cg10483112 chr5:95245456 ELL2 -0.36 -6.28 -0.32 1.04e-9 IgG glycosylation; LIHC cis rs765787 0.530 rs11636395 chr15:45535684 G/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.73 -0.3 2.17e-8 Uric acid levels; LIHC cis rs6500602 0.702 rs4786493 chr16:4500122 C/T cg08645402 chr16:4508243 NA 0.47 9.4 0.45 8.21e-19 Schizophrenia; LIHC cis rs2439831 0.867 rs2278860 chr15:43659046 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.93 -17.48 -0.69 2.41e-49 Lung cancer in ever smokers; LIHC cis rs8031584 1.000 rs890159 chr15:31291634 G/A cg08109568 chr15:31115862 NA -0.42 -5.88 -0.3 9.59e-9 Huntington's disease progression; LIHC cis rs34375054 0.573 rs12579211 chr12:125647752 C/T cg25124228 chr12:125621409 AACS -0.43 -6.68 -0.34 9.67e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs477895 1.000 rs7938380 chr11:64034866 G/A cg18225595 chr11:63971243 STIP1 0.64 6.55 0.33 2.15e-10 Mean platelet volume; LIHC cis rs1215050 0.740 rs9994227 chr4:98767094 T/G cg05340658 chr4:99064831 C4orf37 0.4 5.88 0.3 9.88e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs644799 1.000 rs527899 chr11:95529242 T/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs7246657 0.943 rs10420722 chr19:37973774 C/G cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.45e-9 Coronary artery calcification; LIHC cis rs4237845 0.537 rs12312955 chr12:58265223 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.58 8.04 0.4 1.5e-14 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs77633900 0.772 rs284907 chr15:76741569 A/G cg21673338 chr15:77095150 SCAPER -0.5 -5.83 -0.3 1.31e-8 Non-glioblastoma glioma;Glioma; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg24385632 chr11:16838615 PLEKHA7 0.45 6.67 0.34 1.04e-10 Alopecia areata; LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg02782426 chr3:40428986 ENTPD3 -0.35 -6.46 -0.33 3.52e-10 Renal cell carcinoma; LIHC cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg03060546 chr3:49711283 APEH 0.4 6.01 0.31 4.77e-9 Menarche (age at onset); LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs7523273 0.606 rs2724387 chr1:207932617 T/G cg22525895 chr1:207977042 MIR29B2 0.62 10.14 0.48 2.63e-21 Schizophrenia; LIHC cis rs72627509 0.951 rs72627508 chr4:57831564 C/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.6 -8.7 -0.43 1.46e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs6570726 0.764 rs9386125 chr6:145911677 C/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.31 -0.32 8.87e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7582180 0.614 rs4149518 chr2:101013649 A/G cg14675211 chr2:100938903 LONRF2 0.54 8.24 0.41 3.59e-15 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.554 rs4488814 chr3:10002400 C/T cg21531657 chr3:10005747 TMEM111 -0.39 -5.93 -0.31 7.5e-9 Alzheimer's disease; LIHC cis rs875971 0.895 rs4718349 chr7:65909011 C/G cg11764359 chr7:65958608 NA 0.88 15.8 0.65 1.25e-42 Aortic root size; LIHC cis rs116095464 0.558 rs7736600 chr5:231337 A/C cg22496380 chr5:211416 CCDC127 -1.03 -10.61 -0.5 6.24e-23 Breast cancer; LIHC cis rs10463316 0.817 rs12653378 chr5:150802366 A/G cg03212797 chr5:150827313 SLC36A1 -0.41 -6.2 -0.32 1.6e-9 Metabolite levels (Pyroglutamine); LIHC cis rs6089829 0.855 rs4809459 chr20:61661345 C/T cg03213289 chr20:61660250 NA 0.51 9.1 0.44 7.55e-18 Prostate cancer (SNP x SNP interaction); LIHC cis rs11229555 0.834 rs7925560 chr11:58263036 G/A cg15696309 chr11:58395628 NA -0.7 -8.28 -0.41 2.76e-15 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2204008 0.837 rs11519926 chr12:38348992 G/A cg26384229 chr12:38710491 ALG10B 0.87 10.79 0.5 1.54e-23 Bladder cancer; LIHC cis rs1552244 0.554 rs13079240 chr3:10047246 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC cis rs7582180 0.629 rs6736576 chr2:100950854 C/T cg14675211 chr2:100938903 LONRF2 0.53 8.58 0.42 3.45e-16 Intelligence (multi-trait analysis); LIHC cis rs68170813 0.559 rs74925723 chr7:106954536 G/C cg02696742 chr7:106810147 HBP1 -0.51 -5.88 -0.3 9.71e-9 Coronary artery disease; LIHC cis rs798554 0.959 rs798528 chr7:2772431 A/C cg04166393 chr7:2884313 GNA12 0.42 5.95 0.31 6.61e-9 Height; LIHC cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg18867708 chr6:26865862 GUSBL1 -0.5 -7.62 -0.38 2.58e-13 Schizophrenia; LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg24209194 chr3:40518798 ZNF619 0.56 8.1 0.4 9.68e-15 Renal cell carcinoma; LIHC cis rs2346177 0.781 rs1447563 chr2:46637364 A/C cg02822958 chr2:46747628 ATP6V1E2 0.4 6.13 0.31 2.44e-9 HDL cholesterol; LIHC cis rs2108225 0.872 rs2051955 chr7:107441154 C/T cg18560240 chr7:107437656 SLC26A3 -0.49 -7.49 -0.38 5.97e-13 Ulcerative colitis; LIHC cis rs2257205 0.667 rs9904996 chr17:56711707 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs897984 0.683 rs72799316 chr16:30827205 A/G cg00531865 chr16:30841666 NA -0.38 -6.34 -0.32 7.24e-10 Dementia with Lewy bodies; LIHC cis rs929354 1.000 rs8101 chr7:157061474 A/G cg17757837 chr7:157058334 UBE3C -0.79 -13.7 -0.6 2.34e-34 Body mass index; LIHC cis rs7772486 0.875 rs6570738 chr6:146412695 G/A cg05347473 chr6:146136440 FBXO30 0.35 5.75 0.3 2.01e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg11644478 chr21:40555479 PSMG1 -0.38 -5.85 -0.3 1.12e-8 Cognitive function; LIHC cis rs1577917 1.000 rs6936048 chr6:86702608 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.38 -0.33 5.85e-10 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs7766852 chr6:8472417 C/T cg21535247 chr6:8435926 SLC35B3 0.6 7.83 0.39 6.3e-14 Motion sickness; LIHC cis rs1953600 0.521 rs7067644 chr10:81924245 A/G cg27417294 chr10:81904244 PLAC9 0.36 5.93 0.31 7.52e-9 Sarcoidosis; LIHC cis rs7208859 0.623 rs1054400 chr17:29109954 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs35146811 0.844 rs10281368 chr7:99655897 A/G cg22906224 chr7:99728672 NA 0.44 6.3 0.32 9.33e-10 Coronary artery disease; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs172166 0.652 rs476167 chr6:28065888 T/C cg25329415 chr6:28076851 NA 0.27 5.71 0.3 2.44e-8 Cardiac Troponin-T levels; LIHC cis rs72781680 0.898 rs2879640 chr2:24043573 T/C cg08917208 chr2:24149416 ATAD2B 0.86 8.07 0.4 1.19e-14 Lymphocyte counts; LIHC cis rs875971 0.825 rs10281499 chr7:66048966 A/G cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.22e-34 Aortic root size; LIHC cis rs929354 0.772 rs1182442 chr7:157026633 G/A cg05182265 chr7:156933206 UBE3C 0.32 6.11 0.31 2.78e-9 Body mass index; LIHC cis rs7937682 0.921 rs11213940 chr11:111433927 C/A cg09085632 chr11:111637200 PPP2R1B 0.8 9.16 0.44 4.96e-18 Primary sclerosing cholangitis; LIHC cis rs11690935 0.589 rs2271758 chr2:172701157 T/G cg13550731 chr2:172543902 DYNC1I2 0.64 11.3 0.52 2.21e-25 Schizophrenia; LIHC cis rs7116495 1.000 rs550230 chr11:71602222 A/G cg26138937 chr11:71823887 C11orf51 0.69 6.9 0.35 2.48e-11 Severe influenza A (H1N1) infection; LIHC cis rs921968 0.565 rs35358516 chr2:219625723 A/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs4919087 0.810 rs10736115 chr10:99031685 A/G cg25902810 chr10:99078978 FRAT1 0.65 9.56 0.46 2.42e-19 Monocyte count; LIHC cis rs67311347 0.955 rs4973999 chr3:40460383 G/A cg24209194 chr3:40518798 ZNF619 0.45 6.6 0.34 1.56e-10 Renal cell carcinoma; LIHC cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg07424592 chr7:64974309 NA 0.8 9.08 0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs10493773 0.928 rs12741600 chr1:86191172 A/C cg17807903 chr1:86174739 ZNHIT6 -0.5 -8.3 -0.41 2.45e-15 Urate levels in overweight individuals; LIHC cis rs17685 0.796 rs3757594 chr7:75678644 G/A cg16684958 chr7:75615977 POR -0.5 -8.48 -0.42 6.66e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1983891 0.954 rs4714481 chr6:41521110 T/C cg20194872 chr6:41519635 FOXP4 0.42 6.61 0.34 1.48e-10 Prostate cancer; LIHC cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg09455208 chr3:40491958 NA 0.34 6.78 0.34 5.27e-11 Renal cell carcinoma; LIHC cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg16497277 chr3:49208875 KLHDC8B -0.51 -6.41 -0.33 4.72e-10 Menarche (age at onset); LIHC cis rs16912285 0.688 rs12284649 chr11:24316260 T/A ch.11.24196551F chr11:24239977 NA 0.75 9.83 0.47 2.93e-20 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs28830936 1.000 rs17678767 chr15:42096422 C/G cg17847044 chr15:42102381 MAPKBP1 -0.33 -6.68 -0.34 9.73e-11 Diastolic blood pressure; LIHC cis rs10751667 0.621 rs7394862 chr11:927500 T/C cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC trans rs10213084 1.000 rs13115724 chr4:147510680 A/C cg18061433 chr10:21435895 C10orf113;NEBL 0.47 6.04 0.31 3.94e-9 Heart rate; LIHC cis rs7095607 0.606 rs7084233 chr10:69958343 T/C cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.66e-9 Lung function (FVC); LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg10755058 chr3:40428713 ENTPD3 0.41 7.05 0.36 9.73e-12 Renal cell carcinoma; LIHC cis rs2439831 0.850 rs10438303 chr15:44016417 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.35 0.41 1.67e-15 Lung cancer in ever smokers; LIHC trans rs877282 0.733 rs7092976 chr10:756358 G/A cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs875971 0.862 rs6460279 chr7:65662761 T/C cg18876405 chr7:65276391 NA -0.35 -6.39 -0.33 5.29e-10 Aortic root size; LIHC cis rs722599 0.748 rs1059326 chr14:75369385 C/T cg08847533 chr14:75593920 NEK9 -0.54 -8.77 -0.43 8.3e-17 IgG glycosylation; LIHC cis rs2841277 0.616 rs1048257 chr14:105404384 T/C cg21017887 chr14:105400489 NA 0.66 12.76 0.57 9.24e-31 Rheumatoid arthritis; LIHC trans rs711244 0.541 rs12478822 chr2:37048951 C/G cg21937867 chr17:74536062 PRCD -0.33 -6.29 -0.32 9.93e-10 Mean platelet volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06738889 chr1:150208936 ANP32E 0.49 7.72 0.39 1.25e-13 Pancreatic cancer; LIHC cis rs3008870 1.000 rs2985824 chr1:67410171 C/T cg02640540 chr1:67518911 SLC35D1 -0.43 -5.94 -0.31 6.85e-9 Lymphocyte percentage of white cells; LIHC cis rs10028773 0.515 rs9994488 chr4:120587781 C/T cg09307838 chr4:120376055 NA 0.49 7.08 0.36 8.15e-12 Educational attainment; LIHC cis rs7534824 0.543 rs61780317 chr1:101407139 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.57 0.38 3.49e-13 Refractive astigmatism; LIHC cis rs929354 0.742 rs7801905 chr7:156940111 T/C cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs8017423 0.967 rs11844225 chr14:90726676 G/A cg04374321 chr14:90722782 PSMC1 0.77 15.36 0.64 7.26e-41 Mortality in heart failure; LIHC cis rs798554 0.600 rs2679259 chr7:2885322 C/G cg19717773 chr7:2847554 GNA12 -0.32 -5.88 -0.3 9.54e-9 Height; LIHC cis rs9394841 0.692 rs9394834 chr6:41806793 G/A cg17623882 chr6:41773611 USP49 -0.43 -5.85 -0.3 1.13e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs4808199 1.000 rs4808199 chr19:19545099 C/T cg03709012 chr19:19516395 GATAD2A 1.13 19.41 0.72 4.04e-57 Nonalcoholic fatty liver disease; LIHC cis rs12744310 1.000 rs34190295 chr1:41765879 T/C cg03962019 chr1:41807865 NA 0.38 6.22 0.32 1.46e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs155076 1.000 rs261431 chr13:21865738 A/G cg14456004 chr13:21872349 NA 0.98 10.99 0.51 2.84e-24 White matter hyperintensity burden; LIHC cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg02353165 chr6:42928485 GNMT 0.76 11.91 0.54 1.33e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9549367 0.826 rs1885688 chr13:113894236 G/T cg18105134 chr13:113819100 PROZ -0.58 -10.29 -0.49 8e-22 Platelet distribution width; LIHC cis rs2303759 0.918 rs2288480 chr19:49867016 C/G cg22590775 chr19:49891494 CCDC155 0.47 7.78 0.39 8.57e-14 Multiple sclerosis; LIHC cis rs72634258 0.554 rs34020118 chr1:7895015 C/T cg26816564 chr1:7831052 VAMP3 0.67 5.78 0.3 1.65e-8 Inflammatory bowel disease; LIHC cis rs3762637 0.941 rs112768052 chr3:122169384 G/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs1577917 0.958 rs11755048 chr6:86514334 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.27 -0.49 9.26e-22 Response to antipsychotic treatment; LIHC cis rs9325144 0.560 rs11183046 chr12:38655270 A/T cg26384229 chr12:38710491 ALG10B -0.59 -8.11 -0.4 8.86e-15 Morning vs. evening chronotype; LIHC trans rs10242455 0.571 rs56167514 chr7:99161347 A/G cg09045935 chr12:6379348 NA 0.93 8.01 0.4 1.85e-14 Blood metabolite levels; LIHC cis rs614226 1.000 rs541126 chr12:120972396 C/T cg01236616 chr12:121019343 POP5 -1.29 -19.21 -0.72 2.54e-56 Type 1 diabetes nephropathy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07017693 chr10:71912317 SAR1A -0.42 -6.3 -0.32 9.31e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs919433 0.679 rs7600862 chr2:198534514 C/T cg03934865 chr2:198174659 NA 0.46 6.88 0.35 2.82e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6062302 0.522 rs3787112 chr20:62222411 G/A cg09650180 chr20:62225654 GMEB2 -0.37 -5.8 -0.3 1.49e-8 Glioblastoma; LIHC cis rs35110281 0.774 rs2838321 chr21:44995488 A/T cg21573476 chr21:45109991 RRP1B -0.53 -9.96 -0.47 1.13e-20 Mean corpuscular volume; LIHC cis rs2180341 0.814 rs9401959 chr6:127736464 T/C cg24812749 chr6:127587940 RNF146 0.79 12.59 0.56 4.04e-30 Breast cancer; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.36 0.61 6.46e-37 Prudent dietary pattern; LIHC trans rs11098499 0.874 rs6822498 chr4:120120183 T/C cg25214090 chr10:38739885 LOC399744 0.45 7.27 0.37 2.49e-12 Corneal astigmatism; LIHC cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg23758822 chr17:41437982 NA 0.94 17.78 0.69 1.48e-50 Menopause (age at onset); LIHC cis rs9911578 1.000 rs9897326 chr17:56902297 A/G cg12560992 chr17:57184187 TRIM37 0.96 17.37 0.68 6.51e-49 Intelligence (multi-trait analysis); LIHC cis rs1144333 0.655 rs17097695 chr1:76387258 A/C cg10523679 chr1:76189770 ACADM 0.46 6.2 0.32 1.67e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs4474465 1.000 rs6592779 chr11:78197283 G/C cg27205649 chr11:78285834 NARS2 -0.41 -6.03 -0.31 4.27e-9 Alzheimer's disease (survival time); LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg26338869 chr17:61819248 STRADA 0.61 8.82 0.43 5.97e-17 Prudent dietary pattern; LIHC cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg21171335 chr12:122356390 WDR66 -0.55 -9.37 -0.45 1.04e-18 Mean corpuscular volume; LIHC cis rs9420 0.961 rs11604325 chr11:57497011 C/A cg19752551 chr11:57585705 CTNND1 -0.53 -7.39 -0.37 1.16e-12 Schizophrenia; LIHC cis rs1728785 1.000 rs11075680 chr16:68565700 G/C cg02972257 chr16:68554789 NA -0.53 -6.19 -0.32 1.73e-9 Ulcerative colitis; LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs8062405 0.755 rs62034350 chr16:28562256 A/G cg16576597 chr16:28551801 NUPR1 0.49 7.76 0.39 9.79e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7613875 0.600 rs2624826 chr3:50155468 T/G cg24110177 chr3:50126178 RBM5 0.58 9.59 0.46 1.86e-19 Body mass index; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs769267 0.931 rs15622 chr19:19468734 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.6 -9.47 -0.46 4.59e-19 Tonsillectomy; LIHC cis rs10876993 0.826 rs1678534 chr12:58057435 A/C cg18357645 chr12:58087776 OS9 0.52 8.59 0.42 3.04e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs6430585 0.536 rs60397494 chr2:136470219 C/T cg07169764 chr2:136633963 MCM6 0.75 9.37 0.45 1.01e-18 Corneal structure; LIHC cis rs17608059 0.566 rs5005684 chr17:13910633 T/C cg11395062 chr17:14139857 CDRT15 0.53 9.52 0.46 3.17e-19 Temperament; LIHC cis rs916888 0.821 rs199525 chr17:44847834 T/G cg15921436 chr17:44337874 NA 0.65 6.43 0.33 4.22e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg16743903 chr16:89593216 SPG7 -0.3 -5.78 -0.3 1.72e-8 Multiple myeloma (IgH translocation); LIHC cis rs9611565 0.506 rs2024567 chr22:41699206 G/C cg03806693 chr22:41940476 POLR3H -0.71 -8.44 -0.42 8.82e-16 Vitiligo; LIHC cis rs6952808 0.756 rs12537348 chr7:1948172 C/G cg21782813 chr7:2030301 MAD1L1 0.48 8.12 0.4 8.31e-15 Bipolar disorder and schizophrenia; LIHC cis rs477692 1.000 rs548390 chr10:131417427 G/A cg05714579 chr10:131428358 MGMT 0.45 7.35 0.37 1.43e-12 Response to temozolomide; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08206623 chr11:2907334 CDKN1C 0.62 8.46 0.42 7.7e-16 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15044954 chr7:89874365 C7orf63 0.52 7.24 0.36 2.97e-12 Pancreatic cancer; LIHC cis rs9814567 0.712 rs9838621 chr3:134332319 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8064024 0.513 rs1049207 chr16:4934564 C/G cg08329684 chr16:4932620 PPL -0.42 -7.46 -0.37 7.4e-13 Cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05663655 chr7:107532014 DLD 0.45 6.14 0.32 2.31e-9 Pancreatic cancer; LIHC cis rs9473924 0.542 rs55648125 chr6:50816718 A/G cg14470998 chr6:50812995 TFAP2B 1.03 8.21 0.41 4.52e-15 Body mass index; LIHC cis rs1003719 0.641 rs13046844 chr21:38517603 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.15 -0.52 7.67e-25 Eye color traits; LIHC cis rs2070488 1.000 rs2268758 chr3:38514049 C/T cg24069376 chr3:38537580 EXOG 0.42 7.76 0.39 9.78e-14 Electrocardiographic conduction measures; LIHC cis rs2842992 0.789 rs9365093 chr6:160175819 C/G cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.85 0.54 2.3e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs9303401 0.659 rs7223708 chr17:56896398 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.19 0.55 1.22e-28 Cognitive test performance; LIHC cis rs17685 0.753 rs6951808 chr7:75772413 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10197940 0.578 rs6718372 chr2:152345871 C/G cg19508488 chr2:152266495 RIF1 0.48 6.8 0.35 4.58e-11 Lung cancer; LIHC cis rs763121 0.853 rs6519119 chr22:38989007 C/G cg06022373 chr22:39101656 GTPBP1 0.69 11.97 0.54 8.25e-28 Menopause (age at onset); LIHC cis rs6840360 0.615 rs3828546 chr4:152679816 A/G cg22705602 chr4:152727874 NA -0.4 -8.36 -0.41 1.65e-15 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26600917 chr1:110162534 AMPD2 0.46 6.68 0.34 9.77e-11 Lung function (FEV1/FVC); LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg02993280 chr1:107599747 PRMT6 0.67 10.62 0.5 5.97e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs507080 0.922 rs12796373 chr11:118554939 G/A cg04173919 chr11:118528438 PHLDB1 0.33 6.24 0.32 1.33e-9 Serum metabolite levels; LIHC cis rs17152411 0.895 rs11245420 chr10:126586469 T/C cg07906193 chr10:126599966 NA 0.44 6.89 0.35 2.74e-11 Height; LIHC cis rs7552404 1.000 rs7518038 chr1:76154430 G/A cg22875332 chr1:76189707 ACADM 0.48 6.96 0.35 1.76e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs12701220 0.522 rs1881116 chr7:1053958 C/T cg09177884 chr7:1199841 ZFAND2A -0.49 -6.19 -0.32 1.71e-9 Bronchopulmonary dysplasia; LIHC cis rs4474465 0.915 rs12272791 chr11:78159426 G/A cg27205649 chr11:78285834 NARS2 -0.39 -5.74 -0.3 2.1e-8 Alzheimer's disease (survival time); LIHC cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg21171335 chr12:122356390 WDR66 0.55 8.01 0.4 1.88e-14 Mean corpuscular volume; LIHC cis rs7572733 0.534 rs7572123 chr2:198769637 A/G cg03934865 chr2:198174659 NA 0.47 6.77 0.34 5.59e-11 Dermatomyositis; LIHC cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.84 0.3 1.25e-8 Bipolar disorder; LIHC cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg08125733 chr17:73851984 WBP2 0.94 13.69 0.6 2.5e-34 Psoriasis; LIHC cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.93 0.31 7.42e-9 Schizophrenia; LIHC cis rs7534824 0.625 rs61782078 chr1:101498212 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 7.36 0.37 1.42e-12 Refractive astigmatism; LIHC cis rs1348850 0.519 rs1527407 chr2:178525630 T/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.04 0.4 1.53e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6547741 0.775 rs11692692 chr2:27861707 G/A cg27432699 chr2:27873401 GPN1 -0.92 -16.04 -0.66 1.46e-43 Oral cavity cancer; LIHC trans rs3743102 0.591 rs17841171 chr15:83358388 C/T cg01542190 chr22:50604728 NA 0.56 7.7 0.38 1.53e-13 Colorectal adenoma (advanced); LIHC cis rs2242116 0.727 rs4683298 chr3:46966387 C/G cg02527881 chr3:46936655 PTH1R -0.48 -10.31 -0.49 7.25e-22 Birth weight; LIHC cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg12379764 chr21:47803548 PCNT -0.56 -8.38 -0.41 1.42e-15 Testicular germ cell tumor; LIHC trans rs875971 0.964 rs1643388 chr7:65844562 T/C cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg13393036 chr8:95962371 TP53INP1 -0.4 -8.96 -0.44 2.18e-17 Type 2 diabetes; LIHC trans rs1814175 0.935 rs11040462 chr11:49683158 G/A cg03929089 chr4:120376271 NA -0.89 -17.61 -0.69 7.36e-50 Height; LIHC cis rs1023500 0.551 rs2301521 chr22:42423110 G/C cg05082376 chr22:42548792 NA -0.41 -5.84 -0.3 1.25e-8 Schizophrenia; LIHC cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.01 0.31 4.83e-9 Menopause (age at onset); LIHC cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg06453172 chr10:134556979 INPP5A -0.63 -8.85 -0.43 4.9e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2637030 0.559 rs256117 chr5:52916684 G/A cg06476337 chr5:52856530 NDUFS4 0.43 6.82 0.35 4.25e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 12.63 0.56 2.73e-30 Alzheimer's disease; LIHC trans rs11088226 0.681 rs11702499 chr21:33938565 C/T cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.1e-34 Gastritis; LIHC cis rs7131987 0.650 rs7301398 chr12:29455390 G/T cg12903224 chr12:29470962 FAR2 -0.4 -6.55 -0.33 2.1e-10 QT interval; LIHC trans rs859980 0.514 rs9386402 chr6:104519786 C/T cg26891649 chr19:36239208 LIN37 0.42 6.21 0.32 1.53e-9 Tourette's syndrome or obsessive-compulsive disorder; LIHC cis rs8017423 0.967 rs1005788 chr14:90692747 C/T cg04374321 chr14:90722782 PSMC1 0.73 14.01 0.6 1.47e-35 Mortality in heart failure; LIHC cis rs4901869 1.000 rs4901869 chr14:59334128 A/G cg02291164 chr14:59296302 NA 0.46 5.91 0.3 8.47e-9 Panic disorder; LIHC cis rs11676348 0.808 rs1008563 chr2:219026888 G/A cg00012203 chr2:219082015 ARPC2 -0.49 -6.29 -0.32 9.75e-10 Ulcerative colitis; LIHC cis rs881375 0.678 rs10818488 chr9:123705087 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 6.09 0.31 3.01e-9 Rheumatoid arthritis; LIHC cis rs4555082 0.834 rs2816652 chr14:105712493 C/T cg06808227 chr14:105710500 BRF1 -0.49 -6.14 -0.32 2.23e-9 Mean platelet volume;Platelet distribution width; LIHC trans rs11098499 0.874 rs9995277 chr4:120108603 G/A cg25214090 chr10:38739885 LOC399744 0.45 7.26 0.37 2.6e-12 Corneal astigmatism; LIHC cis rs8016982 0.674 rs1951614 chr14:81672106 A/G cg01989461 chr14:81687754 GTF2A1 -0.7 -14.39 -0.61 4.79e-37 Schizophrenia; LIHC cis rs1775715 1.000 rs1251363 chr10:32328526 G/C cg14930904 chr10:32216787 ARHGAP12 -0.41 -7.23 -0.36 3.09e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg11062466 chr8:58055876 NA 0.4 5.97 0.31 6.07e-9 Developmental language disorder (linguistic errors); LIHC cis rs7408868 1.000 rs10422818 chr19:15285272 A/G cg14696996 chr19:15285081 NOTCH3 0.57 7.57 0.38 3.55e-13 Pulse pressure; LIHC cis rs965469 0.779 rs6051693 chr20:3244449 T/G cg25506879 chr20:3388711 C20orf194 -0.52 -6.33 -0.32 7.92e-10 IFN-related cytopenia; LIHC cis rs8032158 1.000 rs67505007 chr15:56196253 C/T cg24530489 chr15:56299380 NA 0.43 6.01 0.31 4.81e-9 Keloid; LIHC cis rs2115536 0.692 rs6495450 chr15:80162499 C/A cg11839771 chr15:80205821 ST20 -0.32 -6.89 -0.35 2.67e-11 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg08888203 chr3:10149979 C3orf24 0.53 6.43 0.33 4.35e-10 Alzheimer's disease; LIHC cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg27170947 chr2:26402098 FAM59B 0.65 8.31 0.41 2.31e-15 Gut microbiome composition (summer); LIHC cis rs10464366 0.544 rs9639812 chr7:39192058 C/T cg20302533 chr7:39170763 POU6F2 0.37 6.69 0.34 9.14e-11 IgG glycosylation; LIHC cis rs12220238 0.841 rs10824163 chr10:76136589 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.2 0.32 1.66e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9486719 1.000 rs10457159 chr6:96993139 G/A cg06623918 chr6:96969491 KIAA0776 -0.72 -7.23 -0.36 3.08e-12 Migraine;Coronary artery disease; LIHC cis rs6570726 0.791 rs1509213 chr6:145783360 G/A cg13319975 chr6:146136371 FBXO30 0.4 6.1 0.31 2.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10791323 0.628 rs2851118 chr11:133705995 A/C cg06766960 chr11:133703094 NA -0.66 -10.98 -0.51 3.27e-24 Childhood ear infection; LIHC cis rs6952808 0.771 rs4719336 chr7:1916397 T/C cg20295408 chr7:1910781 MAD1L1 -0.52 -7.42 -0.37 9.12e-13 Bipolar disorder and schizophrenia; LIHC cis rs3815700 1.000 rs8104328 chr19:33094371 G/A cg02997394 chr19:33096574 ANKRD27 0.72 9.4 0.45 7.97e-19 Eosinophilic esophagitis; LIHC cis rs2236918 1.000 rs1635511 chr1:242026172 C/T cg17736920 chr1:242011382 EXO1 0.61 9.13 0.44 6.25e-18 Menopause (age at onset); LIHC cis rs311392 0.554 rs2666884 chr8:55100906 T/C cg20636351 chr8:55087400 NA -0.35 -7.16 -0.36 5.02e-12 Pelvic organ prolapse (moderate/severe); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08606075 chr2:677472 TMEM18 -0.49 -6.11 -0.31 2.66e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2991971 0.967 rs12133294 chr1:45988764 C/T cg15605315 chr1:45957053 TESK2 0.47 6.35 0.32 6.74e-10 High light scatter reticulocyte count; LIHC trans rs11098499 0.913 rs67073020 chr4:120152557 C/T cg25214090 chr10:38739885 LOC399744 0.55 8.16 0.4 6.69e-15 Corneal astigmatism; LIHC trans rs208520 0.837 rs208471 chr6:66916749 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.7 -7.79 -0.39 8.3e-14 Exhaled nitric oxide output; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25201980 chr8:146127417 ZNF250 0.4 6.17 0.32 1.98e-9 Pancreatic cancer; LIHC cis rs7903847 0.642 rs2297668 chr10:99160046 C/T cg08345082 chr10:99160200 RRP12 -0.39 -6.64 -0.34 1.23e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7937682 0.883 rs12804962 chr11:111442683 A/T cg09085632 chr11:111637200 PPP2R1B 0.89 10.73 0.5 2.34e-23 Primary sclerosing cholangitis; LIHC cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.1 -0.48 3.53e-21 Platelet count; LIHC cis rs644799 1.000 rs546809 chr11:95579938 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.77 0.47 4.76e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs950776 0.714 rs660652 chr15:78887832 A/G cg06917634 chr15:78832804 PSMA4 -0.59 -8.01 -0.4 1.77e-14 Sudden cardiac arrest; LIHC cis rs6088590 0.561 rs6087605 chr20:33180624 G/T cg08999081 chr20:33150536 PIGU 0.69 13.73 0.6 1.86e-34 Coronary artery disease; LIHC cis rs7119038 0.818 rs3889239 chr11:118619960 C/T cg19308663 chr11:118741387 NA 0.43 5.76 0.3 1.86e-8 Sjögren's syndrome; LIHC cis rs4919694 1.000 rs77827514 chr10:104822009 C/T cg04362960 chr10:104952993 NT5C2 1.14 8.85 0.43 4.77e-17 Arsenic metabolism; LIHC cis rs6964587 1.000 rs10488510 chr7:91660225 G/T cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs4665809 1.000 rs4665306 chr2:26319124 C/T cg27170947 chr2:26402098 FAM59B -0.62 -7.71 -0.38 1.37e-13 Gut microbiome composition (summer); LIHC cis rs1577917 1.000 rs12201571 chr6:86609750 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.21 -0.36 3.63e-12 Response to antipsychotic treatment; LIHC cis rs4555082 0.874 rs28785556 chr14:105745388 A/T cg06808227 chr14:105710500 BRF1 -0.5 -6.11 -0.31 2.74e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs13161895 1.000 rs864482 chr5:179427873 A/G cg06664874 chr5:179499304 RNF130 0.58 7.09 0.36 7.61e-12 LDL cholesterol; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg13099829 chr1:2237991 SKI 0.44 6.45 0.33 3.71e-10 Neuroblastoma; LIHC cis rs2806561 0.765 rs681395 chr1:23500314 G/A cg12483005 chr1:23474871 LUZP1 0.48 7.57 0.38 3.54e-13 Height; LIHC cis rs7149337 0.869 rs10137481 chr14:51694614 C/T cg23942311 chr14:51606299 NA 0.29 5.77 0.3 1.82e-8 Cancer; LIHC cis rs6674970 0.627 rs2864700 chr1:151028929 C/T cg04469105 chr1:151031679 CDC42SE1;MLLT11 -0.43 -5.75 -0.3 2.03e-8 Childhood ear infection; LIHC cis rs7772486 0.754 rs697054 chr6:146003770 C/T cg13319975 chr6:146136371 FBXO30 -0.42 -6.8 -0.35 4.64e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs950169 0.922 rs11630760 chr15:85113337 G/T cg17507749 chr15:85114479 UBE2QP1 0.78 8.96 0.44 2.18e-17 Schizophrenia; LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC trans rs7668874 0.779 rs7688185 chr4:116779145 T/G cg08917878 chr5:172668965 NA -0.3 -6.1 -0.31 2.8e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs921968 0.509 rs3856548 chr2:219398164 C/T cg02176678 chr2:219576539 TTLL4 -0.55 -7.7 -0.38 1.5e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg07157834 chr1:205819609 PM20D1 0.64 9.66 0.46 1.14e-19 Menarche (age at onset); LIHC cis rs4742903 0.935 rs726203 chr9:106906437 A/G cg14250997 chr9:106856677 SMC2 0.41 7.33 0.37 1.71e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs10791323 0.633 rs2171006 chr11:133728323 T/C cg06766960 chr11:133703094 NA -0.6 -9.4 -0.45 8.11e-19 Childhood ear infection; LIHC cis rs5769765 0.773 rs4075331 chr22:50302850 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -9.32 -0.45 1.46e-18 Schizophrenia; LIHC cis rs4665809 0.878 rs4143538 chr2:26290178 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.3 -0.45 1.7e-18 Gut microbiome composition (summer); LIHC cis rs763121 0.853 rs5750664 chr22:39072769 C/T cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs7107174 0.901 rs2511159 chr11:77974193 G/T cg02023728 chr11:77925099 USP35 -0.44 -8.65 -0.42 2.07e-16 Testicular germ cell tumor; LIHC cis rs2797160 1.000 rs1954361 chr6:126001423 C/G cg05901451 chr6:126070800 HEY2 -0.41 -6.96 -0.35 1.75e-11 Endometrial cancer; LIHC trans rs7615952 0.673 rs9821905 chr3:125620850 A/G cg07211511 chr3:129823064 LOC729375 0.85 8.74 0.43 1.03e-16 Blood pressure (smoking interaction); LIHC cis rs3617 0.625 rs2336558 chr3:52886240 C/T cg11645453 chr3:52864694 ITIH4 -0.23 -6.04 -0.31 3.95e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9303401 0.659 rs3809724 chr17:57061238 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.98 13.52 0.59 1.16e-33 Cognitive test performance; LIHC cis rs9916302 0.861 rs593480 chr17:37453780 A/C cg03013999 chr17:37608204 MED1 -0.36 -6.0 -0.31 5e-9 Glomerular filtration rate (creatinine); LIHC cis rs2180341 0.781 rs877102 chr6:127587086 T/C cg27446573 chr6:127587934 RNF146 0.67 10.1 0.48 3.71e-21 Breast cancer; LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg00656387 chr3:40428638 ENTPD3 -0.5 -8.67 -0.42 1.77e-16 Renal cell carcinoma; LIHC cis rs8038465 0.615 rs4075802 chr15:73963239 A/G cg15420318 chr15:73925796 NPTN 0.44 6.8 0.34 4.76e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.65 9.21 0.45 3.29e-18 Lymphocyte counts; LIHC cis rs13108904 0.557 rs1250095 chr4:1239312 C/T cg16405210 chr4:1374714 KIAA1530 0.7 10.44 0.49 2.57e-22 Obesity-related traits; LIHC cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg25364880 chr3:44379878 C3orf23 0.6 8.46 0.42 8.16e-16 Depressive symptoms; LIHC cis rs6951245 0.786 rs77943789 chr7:1140158 C/T cg22907277 chr7:1156413 C7orf50 0.75 5.9 0.3 8.69e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11608355 0.545 rs35422737 chr12:109911456 A/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs2637266 0.967 rs4553314 chr10:78358244 C/T cg18941641 chr10:78392320 NA 0.3 6.44 0.33 3.94e-10 Pulmonary function; LIHC cis rs6076065 0.707 rs2024746 chr20:23356862 G/A cg11657817 chr20:23433608 CST11 0.32 6.76 0.34 6.12e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs77861329 1.000 rs123681 chr3:52209320 A/G cg08692210 chr3:52188851 WDR51A 0.83 7.96 0.4 2.61e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs921968 0.541 rs490483 chr2:219429052 A/T cg02985541 chr2:219472218 PLCD4 0.42 6.94 0.35 1.94e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg08888203 chr3:10149979 C3orf24 0.44 5.79 0.3 1.57e-8 Alzheimer's disease; LIHC cis rs10769945 0.679 rs7102920 chr11:1917872 C/T cg23202291 chr11:1979235 NA 0.43 6.21 0.32 1.56e-9 DNA methylation (variation); LIHC cis rs765787 0.530 rs1706830 chr15:45516229 G/A cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs17711722 0.653 rs2460421 chr7:65491123 A/T cg26939375 chr7:64535504 NA -0.46 -7.58 -0.38 3.25e-13 Calcium levels; LIHC cis rs28374715 0.733 rs9568 chr15:41573612 G/T cg18705301 chr15:41695430 NDUFAF1 -1.14 -14.84 -0.63 8.28e-39 Ulcerative colitis; LIHC cis rs1790761 0.658 rs666328 chr11:67335538 G/A cg21734168 chr11:67353974 GSTP1 -0.28 -6.8 -0.35 4.59e-11 Mean corpuscular volume; LIHC cis rs4803468 0.967 rs4803462 chr19:41908936 T/A cg09537434 chr19:41945824 ATP5SL -1.01 -21.23 -0.75 2.17e-64 Height; LIHC cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg24642844 chr7:1081250 C7orf50 -0.95 -9.26 -0.45 2.25e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3761218 0.738 rs6084472 chr20:3771858 G/T cg25011176 chr20:3776985 CDC25B -0.41 -5.87 -0.3 1.06e-8 Bipolar disorder; LIHC cis rs826838 0.874 rs844115 chr12:39117384 C/A cg26384229 chr12:38710491 ALG10B -0.56 -7.82 -0.39 6.83e-14 Heart rate; LIHC cis rs2153535 0.580 rs9406170 chr6:8514153 T/C cg23788917 chr6:8435910 SLC35B3 0.62 8.74 0.43 1.08e-16 Motion sickness; LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg06115535 chr2:131100015 IMP4;CCDC115 -0.43 -6.71 -0.34 8.06e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7086627 0.515 rs7088877 chr10:82208860 C/G cg01528321 chr10:82214614 TSPAN14 0.54 7.68 0.38 1.68e-13 Post bronchodilator FEV1; LIHC cis rs12451471 0.529 rs2278620 chr17:78083565 G/A cg06718696 chr17:78121285 EIF4A3 0.94 10.94 0.51 4.31e-24 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs80282103 0.764 rs12244052 chr10:1103266 G/A cg08668510 chr10:1095578 IDI1 0.7 7.0 0.35 1.36e-11 Glomerular filtration rate (creatinine); LIHC trans rs10028773 0.700 rs7690338 chr4:120256468 C/G cg25214090 chr10:38739885 LOC399744 0.51 8.26 0.41 3.23e-15 Educational attainment; LIHC cis rs6570726 0.755 rs2092296 chr6:145893684 A/C cg23711669 chr6:146136114 FBXO30 0.71 12.68 0.57 1.87e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs2839186 1.000 rs2839181 chr21:47685939 A/G cg11766577 chr21:47581405 C21orf56 -0.41 -6.53 -0.33 2.44e-10 Testicular germ cell tumor; LIHC cis rs4819052 0.851 rs8131143 chr21:46671646 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.74 -11.57 -0.53 2.33e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4237845 0.773 rs6650217 chr12:58289072 T/G cg04478727 chr12:58166393 METTL1;FAM119B 0.43 5.95 0.31 6.68e-9 Intelligence (multi-trait analysis); LIHC cis rs1499614 1.000 rs2659911 chr7:66158420 G/A cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC cis rs988712 0.705 rs11030099 chr11:27677583 C/A cg18117895 chr11:27722066 BDNF 0.5 6.81 0.35 4.4e-11 Obesity; LIHC cis rs8017423 0.935 rs7144335 chr14:90732280 A/G cg14092571 chr14:90743983 NA 0.43 6.87 0.35 2.97e-11 Mortality in heart failure; LIHC trans rs10506458 1.000 rs73128779 chr12:63441852 T/G cg22491629 chr6:157744540 C6orf35 -0.58 -10.11 -0.48 3.34e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs4900538 0.963 rs1190553 chr14:102915331 G/T cg18135206 chr14:102964638 TECPR2 -0.94 -16.55 -0.67 1.27e-45 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg02993280 chr1:107599747 PRMT6 0.69 11.3 0.52 2.19e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg07424592 chr7:64974309 NA 0.82 9.64 0.46 1.27e-19 Diabetic kidney disease; LIHC cis rs13108904 0.901 rs6851528 chr4:1296009 G/A cg19318889 chr4:1322082 MAEA 0.53 8.85 0.43 4.76e-17 Obesity-related traits; LIHC cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg13395646 chr4:1353034 KIAA1530 -0.43 -6.21 -0.32 1.57e-9 Longevity; LIHC cis rs9399135 0.967 rs7741626 chr6:135314182 C/T cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.02e-11 Red blood cell count; LIHC cis rs9388451 1.000 rs9388451 chr6:126090377 A/G cg05901451 chr6:126070800 HEY2 -0.75 -16.75 -0.67 2.14e-46 Brugada syndrome; LIHC cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg15320075 chr8:145703422 NA -0.59 -10.41 -0.49 3.06e-22 Age at first birth; LIHC cis rs9381040 0.655 rs4140578 chr6:41041829 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.39 -6.23 -0.32 1.38e-9 Alzheimer's disease (late onset); LIHC cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg05590025 chr7:65112418 INTS4L2 -0.65 -7.33 -0.37 1.68e-12 Diabetic kidney disease; LIHC cis rs1267303 0.642 rs6670699 chr1:46997270 C/T cg25110126 chr1:46999211 NA 0.51 6.92 0.35 2.25e-11 Monobrow; LIHC cis rs7465272 1.000 rs7835613 chr8:143682428 C/T cg10104451 chr8:143696006 ARC -0.54 -6.9 -0.35 2.57e-11 Bipolar disorder and schizophrenia; LIHC cis rs9790314 1.000 rs9872514 chr3:161042833 T/C cg03342759 chr3:160939853 NMD3 -0.75 -10.47 -0.49 1.93e-22 Morning vs. evening chronotype; LIHC cis rs6542838 0.554 rs4311103 chr2:99538362 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.4 -5.73 -0.3 2.19e-8 Fear of minor pain; LIHC cis rs17685 0.712 rs10275521 chr7:75770972 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg09455208 chr3:40491958 NA 0.42 8.46 0.42 7.64e-16 Renal cell carcinoma; LIHC cis rs7552404 1.000 rs942270 chr1:76177332 G/A cg10523679 chr1:76189770 ACADM 0.64 8.61 0.42 2.74e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8062405 0.965 rs62037363 chr16:28865042 T/C cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4555082 0.957 rs2816622 chr14:105733114 T/C cg06808227 chr14:105710500 BRF1 -0.56 -7.49 -0.38 5.82e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs12477438 0.798 rs13393860 chr2:99590397 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.06 -14.67 -0.62 3.78e-38 Chronic sinus infection; LIHC cis rs75920871 0.528 rs983567 chr11:116783600 T/C cg01368799 chr11:117014884 PAFAH1B2 -0.46 -5.9 -0.3 8.52e-9 Subjective well-being; LIHC cis rs3857067 0.806 rs6532471 chr4:95108584 T/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.61 -0.38 2.72e-13 QT interval; LIHC cis rs4908768 0.579 rs75634300 chr1:8872455 C/T cg20416874 chr1:8611966 RERE 0.41 6.01 0.31 4.7e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24883642 chr15:40226588 EIF2AK4 0.41 6.17 0.32 1.93e-9 Lung function (FEV1/FVC); LIHC cis rs7618501 0.699 rs3733135 chr3:49939587 G/A cg21467203 chr3:49911342 NA -0.49 -8.53 -0.42 4.89e-16 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.888 rs2892060 chr20:60617955 G/T cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs2153535 0.580 rs4960422 chr6:8459309 T/C cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs9486715 0.793 rs2499777 chr6:97013814 T/C cg06623918 chr6:96969491 KIAA0776 -0.86 -15.33 -0.64 9.77e-41 Headache; LIHC cis rs7927771 1.000 rs34910028 chr11:47758449 T/C cg20135002 chr11:47629003 NA -0.54 -9.26 -0.45 2.36e-18 Subjective well-being; LIHC cis rs6570726 0.935 rs386823 chr6:145841365 C/T cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs73142122 chr7:65311298 C/A cg05590025 chr7:65112418 INTS4L2 -0.6 -6.45 -0.33 3.93e-10 Diabetic kidney disease; LIHC cis rs909341 0.909 rs2427532 chr20:62363817 G/A cg03999872 chr20:62272968 STMN3 -0.45 -6.78 -0.34 5.24e-11 Atopic dermatitis; LIHC cis rs4660306 0.961 rs7546268 chr1:45965340 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.65 -7.91 -0.39 3.51e-14 Homocysteine levels; LIHC trans rs1814175 0.645 rs1851845 chr11:49982396 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs4908768 0.501 rs11121186 chr1:8540341 G/A cg20416874 chr1:8611966 RERE -0.67 -14.02 -0.6 1.3e-35 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.45e-29 Menopause (age at onset); LIHC cis rs1580019 0.520 rs6945238 chr7:32646096 C/T cg07520158 chr7:32535189 LSM5;AVL9 -0.5 -6.89 -0.35 2.69e-11 Cognitive ability; LIHC trans rs634534 0.532 rs12794370 chr11:65770413 G/A cg17712092 chr4:129076599 LARP1B 0.72 12.8 0.57 6.57e-31 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs10744422 1.000 rs10744422 chr12:123336789 T/C cg25930673 chr12:123319894 HIP1R -0.93 -12.33 -0.55 3.7e-29 Schizophrenia; LIHC cis rs8017423 0.935 rs11624246 chr14:90734826 A/G cg04374321 chr14:90722782 PSMC1 -0.77 -14.71 -0.62 2.61e-38 Mortality in heart failure; LIHC cis rs11893307 0.507 rs1465305 chr2:191585392 C/G cg05765582 chr2:191677683 NA 0.29 5.72 0.3 2.39e-8 Mean platelet volume; LIHC cis rs34779708 0.966 rs1148245 chr10:35511894 C/T cg03585969 chr10:35415529 CREM 0.8 11.97 0.54 8.44e-28 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2066819 1.000 rs79750959 chr12:56702012 C/A cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs3849570 1.000 rs13088000 chr3:81839404 T/C cg07356753 chr3:81810745 GBE1 -0.63 -10.32 -0.49 6.64e-22 Waist circumference;Body mass index; LIHC cis rs523522 0.892 rs4767916 chr12:121024032 T/C cg27279351 chr12:120934652 DYNLL1 0.67 11.93 0.54 1.11e-27 High light scatter reticulocyte count; LIHC cis rs8062405 0.691 rs743590 chr16:28608230 G/A cg07451762 chr16:28383216 NA 0.42 7.53 0.38 4.61e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs2832077 0.689 rs2832052 chr21:30130073 G/C cg14791747 chr16:20752902 THUMPD1 0.46 6.78 0.34 5.38e-11 Cognitive test performance; LIHC cis rs9309473 1.000 rs62151652 chr2:73700131 A/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.64 -0.34 1.22e-10 Metabolite levels; LIHC trans rs3780486 0.846 rs10813948 chr9:33121570 G/A cg20290983 chr6:43655470 MRPS18A 1.17 28.71 0.84 3.97e-93 IgG glycosylation; LIHC cis rs17685 0.884 rs3823882 chr7:75631913 T/C cg16684958 chr7:75615977 POR -0.5 -8.47 -0.42 7.2e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35110281 0.776 rs9306159 chr21:45061839 G/T cg04455712 chr21:45112962 RRP1B 0.46 7.86 0.39 5.1e-14 Mean corpuscular volume; LIHC cis rs801193 1.000 rs4279493 chr7:66226620 C/T cg14393609 chr7:65229607 NA 0.37 5.72 0.3 2.3e-8 Aortic root size; LIHC cis rs35110281 0.682 rs162379 chr21:44925334 A/G cg21573476 chr21:45109991 RRP1B 0.43 8.11 0.4 8.89e-15 Mean corpuscular volume; LIHC cis rs9911578 0.692 rs411988 chr17:56709034 G/A cg12560992 chr17:57184187 TRIM37 0.67 8.88 0.43 3.94e-17 Intelligence (multi-trait analysis); LIHC cis rs801193 0.548 rs2659891 chr7:66201114 A/G cg11764359 chr7:65958608 NA 0.75 12.68 0.57 1.77e-30 Aortic root size; LIHC cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg21724239 chr8:58056113 NA 0.45 5.98 0.31 5.49e-9 Developmental language disorder (linguistic errors); LIHC cis rs769267 0.899 rs3934667 chr19:19431423 T/G cg03709012 chr19:19516395 GATAD2A -0.91 -15.52 -0.64 1.65e-41 Tonsillectomy; LIHC cis rs9300255 0.596 rs11057202 chr12:123720775 G/T cg05973401 chr12:123451056 ABCB9 0.43 5.94 0.31 7.13e-9 Neutrophil percentage of white cells; LIHC cis rs7918232 0.941 rs1085782 chr10:27440517 G/A cg14442939 chr10:27389572 ANKRD26 -0.71 -6.72 -0.34 7.44e-11 Breast cancer; LIHC cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg24531977 chr5:56204891 C5orf35 -0.68 -9.42 -0.45 7e-19 Type 2 diabetes; LIHC cis rs709400 0.567 rs11624343 chr14:103859156 T/A cg26031613 chr14:104095156 KLC1 0.8 10.01 0.48 7.23e-21 Body mass index; LIHC cis rs875971 0.862 rs6971059 chr7:66067032 A/G cg11764359 chr7:65958608 NA -0.78 -13.64 -0.59 4.13e-34 Aortic root size; LIHC cis rs12971120 0.838 rs3794950 chr18:72182965 G/A cg25817165 chr18:72167213 CNDP2 -0.69 -11.37 -0.52 1.3e-25 Refractive error; LIHC cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg04317338 chr11:64019027 PLCB3 0.88 11.1 0.51 1.14e-24 Mean platelet volume; LIHC cis rs798554 0.721 rs2527680 chr7:2892361 C/T cg04166393 chr7:2884313 GNA12 0.55 8.78 0.43 8.16e-17 Height; LIHC cis rs4908760 0.539 rs6698830 chr1:8854545 C/T cg20416874 chr1:8611966 RERE -0.57 -10.28 -0.49 8.98e-22 Vitiligo; LIHC cis rs9649213 0.593 rs12704989 chr7:98029438 G/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.81 -0.3 1.41e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs17376456 0.825 rs72786702 chr5:93254656 A/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.6 8.78 0.43 7.81e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs16866061 0.890 rs72972401 chr2:225404668 T/C cg12698349 chr2:225449008 CUL3 0.81 14.18 0.61 3.16e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs7582720 1.000 rs114395475 chr2:203769112 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.21 0.45 3.26e-18 Bipolar disorder; LIHC cis rs13108904 0.901 rs6851528 chr4:1296009 G/A cg20887711 chr4:1340912 KIAA1530 0.6 9.53 0.46 3.07e-19 Obesity-related traits; LIHC cis rs12313068 0.709 rs10849698 chr12:110504798 C/G cg12870014 chr12:110450643 ANKRD13A 0.83 11.04 0.51 1.85e-24 Intelligence (multi-trait analysis); LIHC cis rs986417 0.818 rs10151839 chr14:60980688 T/G cg27398547 chr14:60952738 C14orf39 0.76 8.3 0.41 2.44e-15 Gut microbiota (bacterial taxa); LIHC cis rs9733 0.519 rs72704603 chr1:150707992 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.74 -0.3 2.12e-8 Tonsillectomy; LIHC cis rs12701220 0.817 rs59471534 chr7:1085224 G/A cg18765753 chr7:1198926 ZFAND2A -0.4 -5.83 -0.3 1.26e-8 Bronchopulmonary dysplasia; LIHC cis rs7520050 0.581 rs6671303 chr1:46629653 A/C cg24542714 chr1:46669345 POMGNT1;C1orf190 -0.43 -7.2 -0.36 3.92e-12 Red blood cell count;Reticulocyte count; LIHC cis rs6596100 0.538 rs17594964 chr5:132188712 A/G cg02081065 chr5:132209139 LEAP2 0.29 6.3 0.32 9.39e-10 Breast cancer; LIHC cis rs708547 0.697 rs67479587 chr4:57878884 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.46 6.75 0.34 6.36e-11 Response to bleomycin (chromatid breaks); LIHC cis rs34779708 0.966 rs12774834 chr10:35400070 A/T cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1385374 0.858 rs11059927 chr12:129294333 T/C cg09035930 chr12:129282057 SLC15A4 -0.5 -5.95 -0.31 6.49e-9 Systemic lupus erythematosus; LIHC cis rs9326248 0.817 rs1242127 chr11:117076564 A/G cg10130564 chr11:117069849 TAGLN -0.36 -6.3 -0.32 8.97e-10 Blood protein levels; LIHC cis rs34779708 0.931 rs66887762 chr10:35330577 C/T cg03585969 chr10:35415529 CREM 0.86 13.0 0.58 1.15e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2153535 0.580 rs1577471 chr6:8485905 T/A cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs903552 0.935 rs8041582 chr15:102005851 G/A cg25677261 chr15:102009856 PCSK6 -0.46 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg06844545 chr6:163836348 QKI -0.44 -6.37 -0.33 5.98e-10 Triglycerides; LIHC cis rs7618501 0.501 rs7627864 chr3:49926613 C/G cg21467203 chr3:49911342 NA -0.59 -10.62 -0.5 5.81e-23 Intelligence (multi-trait analysis); LIHC cis rs7395581 0.918 rs1055510 chr11:47292237 A/G cg26139080 chr11:47293733 MADD -0.5 -8.36 -0.41 1.56e-15 HDL cholesterol; LIHC cis rs6504950 0.720 rs9913784 chr17:52989071 A/T cg10237252 chr17:52977213 TOM1L1 -0.41 -7.17 -0.36 4.59e-12 Breast cancer; LIHC cis rs9733 0.596 rs72702573 chr1:150689050 C/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs4132509 0.948 rs12032342 chr1:243834360 G/A cg21452805 chr1:244014465 NA 0.44 5.8 0.3 1.55e-8 RR interval (heart rate); LIHC cis rs9399135 0.967 rs13218642 chr6:135309940 A/G cg24558204 chr6:135376177 HBS1L 0.4 6.54 0.33 2.27e-10 Red blood cell count; LIHC cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 4.04e-13 Bipolar disorder; LIHC cis rs17685 0.712 rs56965035 chr7:75795670 G/A cg04592579 chr7:75616294 TMEM120A 0.41 7.0 0.35 1.33e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg05255149 chr17:80675120 FN3KRP 0.43 6.14 0.32 2.28e-9 Glycated hemoglobin levels; LIHC trans rs2359714 0.935 rs7339896 chr1:118798414 A/G cg19861078 chr7:7936962 NA 0.32 6.11 0.31 2.65e-9 Breast size; LIHC cis rs16828019 0.852 rs35992757 chr1:41652862 C/T cg03962019 chr1:41807865 NA 0.53 7.53 0.38 4.66e-13 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.666 rs4074235 chr11:977511 C/G cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs61990749 0.597 rs7147516 chr14:78153980 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.59 -9.85 -0.47 2.5e-20 Fibroblast growth factor basic levels; LIHC cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg04025307 chr7:1156635 C7orf50 0.57 9.89 0.47 1.94e-20 Longevity;Endometriosis; LIHC cis rs1144333 1.000 rs17097863 chr1:76468787 T/G cg10523679 chr1:76189770 ACADM 0.42 5.94 0.31 6.96e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09109880 chr4:184365620 CDKN2AIP 0.51 6.44 0.33 4.14e-10 Hepatitis; LIHC cis rs9596863 0.898 rs9568915 chr13:54341214 T/C ch.13.53330881F chr13:54432880 NA 0.45 6.1 0.31 2.79e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9733 0.596 rs1415148 chr1:150705755 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs9611565 0.765 rs727563 chr22:41867377 C/T cg03806693 chr22:41940476 POLR3H 0.56 7.5 0.38 5.44e-13 Vitiligo; LIHC cis rs12701220 0.894 rs10263252 chr7:1049949 G/A cg26769984 chr7:1090371 C7orf50 0.57 7.21 0.36 3.51e-12 Bronchopulmonary dysplasia; LIHC cis rs807029 0.577 rs11190786 chr10:102757442 A/G cg27255678 chr10:102756921 LZTS2 0.52 7.27 0.37 2.51e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4908760 0.566 rs7532459 chr1:8677773 C/G cg20416874 chr1:8611966 RERE -0.63 -11.99 -0.54 6.59e-28 Vitiligo; LIHC cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg22764044 chr5:178986830 RUFY1 -0.39 -5.81 -0.3 1.39e-8 Lung cancer; LIHC cis rs9457247 0.967 rs86755 chr6:167403108 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 10.0 0.48 8.15e-21 Crohn's disease; LIHC cis rs9948 0.655 rs57582887 chr2:97406354 A/C cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC cis rs6964587 1.000 rs28735847 chr7:91592755 T/C cg17063962 chr7:91808500 NA 1.02 19.55 0.73 1.15e-57 Breast cancer; LIHC cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg00035636 chr13:21900591 NA 0.37 6.05 0.31 3.71e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06123940 chr18:29597493 RNF125 0.47 7.7 0.38 1.53e-13 Longevity; LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg04013166 chr16:89971882 TCF25 0.61 7.99 0.4 2.07e-14 Skin colour saturation; LIHC cis rs6754311 0.550 rs3213889 chr2:136511575 A/G cg17750252 chr2:136567154 LCT 0.35 6.15 0.32 2.2e-9 Mosquito bite size; LIHC trans rs11098499 0.644 rs34835603 chr4:120553428 C/T cg25214090 chr10:38739885 LOC399744 0.5 8.0 0.4 1.88e-14 Corneal astigmatism; LIHC cis rs10089 1.000 rs2409109 chr5:127461471 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.25e-11 Ileal carcinoids; LIHC cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.48 -6.81 -0.35 4.41e-11 Prostate cancer; LIHC cis rs2777491 0.874 rs11633799 chr15:41576538 G/A cg18705301 chr15:41695430 NDUFAF1 -0.54 -7.53 -0.38 4.56e-13 Ulcerative colitis; LIHC cis rs739401 0.611 rs417957 chr11:3046231 A/G cg05729581 chr11:3078854 CARS -0.42 -5.91 -0.3 8.1e-9 Longevity; LIHC cis rs9911578 1.000 rs9892062 chr17:56976981 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs11030122 0.632 rs714380 chr11:4059653 A/T cg18678763 chr11:4115507 RRM1 -0.57 -8.57 -0.42 3.52e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs35110281 0.720 rs162375 chr21:44927015 C/T cg04455712 chr21:45112962 RRP1B -0.48 -8.01 -0.4 1.83e-14 Mean corpuscular volume; LIHC cis rs6430585 0.528 rs309167 chr2:136669264 C/T cg15123519 chr2:136567270 LCT -0.36 -5.77 -0.3 1.76e-8 Corneal structure; LIHC cis rs7503807 1.000 rs901064 chr17:78596040 C/T cg09596252 chr17:78655493 RPTOR -0.38 -6.79 -0.34 5.04e-11 Obesity; LIHC cis rs1577917 0.958 rs12213431 chr6:86500956 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.86 -0.3 1.07e-8 Response to antipsychotic treatment; LIHC cis rs7615952 0.733 rs13314847 chr3:125644788 C/T cg05084668 chr3:125655381 ALG1L -0.6 -8.5 -0.42 6.02e-16 Blood pressure (smoking interaction); LIHC trans rs10838801 1 rs10838801 chr11:48098280 G/A cg03929089 chr4:120376271 NA -0.46 -6.07 -0.31 3.37e-9 Height; LIHC cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg12756686 chr19:29218302 NA 0.44 7.15 0.36 5.35e-12 Methadone dose in opioid dependence; LIHC cis rs875971 0.862 rs3893216 chr7:65790707 G/C cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC trans rs2727020 0.857 rs1917324 chr11:49371759 G/C cg15704280 chr7:45808275 SEPT13 -0.74 -11.27 -0.52 2.8e-25 Coronary artery disease; LIHC cis rs9486719 0.895 rs34051754 chr6:97007754 A/T cg06623918 chr6:96969491 KIAA0776 -0.71 -7.26 -0.37 2.62e-12 Migraine;Coronary artery disease; LIHC cis rs17376456 0.825 rs55947981 chr5:93278104 G/T cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC trans rs72766638 0.806 rs56303154 chr9:136936376 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.59 -6.51 -0.33 2.65e-10 Mosquito bite size; LIHC cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg05665937 chr4:1216051 CTBP1 0.39 6.2 0.32 1.59e-9 Obesity-related traits; LIHC cis rs600806 0.714 rs2781552 chr1:110025881 A/G cg23091122 chr1:110024289 SYPL2 0.45 6.07 0.31 3.37e-9 Intelligence (multi-trait analysis); LIHC cis rs763121 0.853 rs3827357 chr22:39079413 A/G cg14440974 chr22:39074834 NA -0.45 -7.3 -0.37 2.09e-12 Menopause (age at onset); LIHC cis rs7712401 0.755 rs3756362 chr5:122108890 C/G cg18764291 chr5:122110994 SNX2 0.33 5.82 0.3 1.36e-8 Mean platelet volume; LIHC cis rs912057 1.000 rs912056 chr6:6736197 A/T cg06612196 chr6:6737390 NA 0.5 9.21 0.45 3.26e-18 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs2439831 0.850 rs28858500 chr15:44156942 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.89 0.35 2.71e-11 Lung cancer in ever smokers; LIHC cis rs72781680 1.000 rs6731001 chr2:24192952 A/G cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs10927875 0.864 rs12135073 chr1:16167799 C/T cg07117364 chr1:16154769 NA 0.38 5.72 0.3 2.38e-8 Dilated cardiomyopathy; LIHC cis rs11603020 0.950 rs11229067 chr11:57374946 A/C cg19752551 chr11:57585705 CTNND1 0.46 6.1 0.31 2.89e-9 Blood protein levels; LIHC cis rs6089584 0.821 rs2273990 chr20:60579149 G/T cg06108461 chr20:60628389 TAF4 -0.89 -13.81 -0.6 9.11e-35 Body mass index; LIHC cis rs6963495 0.745 rs73190179 chr7:105162812 C/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs3008870 0.536 rs2208576 chr1:67513401 C/G cg02640540 chr1:67518911 SLC35D1 -0.59 -11.17 -0.52 6.66e-25 Lymphocyte percentage of white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11317019 chr17:42219250 C17orf53 0.38 6.17 0.32 1.9e-9 Cognitive function; LIHC cis rs651907 0.535 rs17412601 chr3:101499275 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg13126279 chr21:47581558 C21orf56 0.44 7.22 0.36 3.46e-12 Testicular germ cell tumor; LIHC cis rs600806 0.665 rs1368988 chr1:110012123 A/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.15 -0.32 2.17e-9 Intelligence (multi-trait analysis); LIHC cis rs2933343 0.700 rs789239 chr3:128633808 T/C cg25356066 chr3:128598488 ACAD9 0.53 7.47 0.37 6.95e-13 IgG glycosylation; LIHC cis rs875622 0.556 rs4808047 chr19:16527834 T/C cg10248733 chr19:16607483 C19orf44;CALR3 -0.7 -7.93 -0.39 3.19e-14 White matter integrity;Neutrophil percentage of white cells; LIHC cis rs1707322 0.721 rs4415615 chr1:46132109 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.57 0.38 3.45e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg05564831 chr3:52568323 NT5DC2 -0.36 -6.01 -0.31 4.88e-9 Electroencephalogram traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08330117 chr8:90770456 RIPK2 0.44 6.18 0.32 1.78e-9 Pancreatic cancer; LIHC cis rs2153535 0.560 rs2210798 chr6:8481522 C/T cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06803689 chr22:29949796 THOC5 -0.46 -6.57 -0.33 1.9e-10 Pancreatic cancer; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg23131131 chr22:24373011 LOC391322 -0.6 -8.62 -0.42 2.59e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg18110333 chr6:292329 DUSP22 -0.59 -8.21 -0.41 4.63e-15 Menopause (age at onset); LIHC trans rs79243044 0.786 rs16932549 chr11:5560909 C/T cg03327327 chr1:214779620 CENPF 0.47 6.08 0.31 3.17e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs919433 0.963 rs6738836 chr2:198182432 A/G cg10820045 chr2:198174542 NA -0.58 -9.75 -0.47 5.68e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2066819 1.000 rs79101914 chr12:56729739 A/G cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs8180040 0.620 rs9845728 chr3:47103376 C/T cg27129171 chr3:47204927 SETD2 0.56 9.35 0.45 1.21e-18 Colorectal cancer; LIHC cis rs9392556 0.509 rs588158 chr6:4079592 G/C cg08342332 chr6:4079704 C6orf201;C6orf146 -0.34 -6.64 -0.34 1.25e-10 Blood metabolite levels; LIHC cis rs1005277 0.529 rs1780125 chr10:38531376 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.37 -0.33 5.99e-10 Extrinsic epigenetic age acceleration; LIHC cis rs11690935 0.549 rs2129475 chr2:172916772 A/G cg13550731 chr2:172543902 DYNC1I2 0.54 9.23 0.45 2.97e-18 Schizophrenia; LIHC cis rs963731 0.649 rs7568552 chr2:39257667 T/C cg04010122 chr2:39346883 SOS1 -0.75 -6.37 -0.33 6.19e-10 Corticobasal degeneration; LIHC cis rs4631830 0.965 rs4306255 chr10:51542444 A/G cg20129853 chr10:51489980 NA -0.41 -8.74 -0.43 1.04e-16 Prostate-specific antigen levels; LIHC cis rs5769707 0.935 rs1109320 chr22:49989106 G/A cg01652190 chr22:50026171 C22orf34 -0.29 -6.61 -0.34 1.52e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs778371 0.871 rs2675954 chr2:233750627 C/G cg08000102 chr2:233561755 GIGYF2 -0.85 -13.55 -0.59 8.73e-34 Schizophrenia; LIHC cis rs7617773 0.817 rs13068265 chr3:48301614 A/C cg11946769 chr3:48343235 NME6 0.9 11.29 0.52 2.51e-25 Coronary artery disease; LIHC cis rs8180040 0.934 rs62260710 chr3:47564462 C/G cg16586182 chr3:47516702 SCAP 0.44 7.47 0.37 6.57e-13 Colorectal cancer; LIHC cis rs4319547 0.619 rs7973869 chr12:122874284 G/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.25 -0.37 2.74e-12 Body mass index; LIHC cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg18357526 chr6:26021779 HIST1H4A -0.53 -6.5 -0.33 2.81e-10 Blood metabolite levels; LIHC cis rs7917772 0.619 rs2801050 chr10:104509393 T/A cg22532475 chr10:104410764 TRIM8 -0.38 -6.69 -0.34 9.11e-11 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6733011 0.508 rs4851173 chr2:99520608 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.2 -0.32 1.58e-9 Bipolar disorder; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg17284865 chr1:155197511 GBAP1 0.38 6.26 0.32 1.16e-9 Bilirubin levels; LIHC cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg06634786 chr22:41940651 POLR3H -0.73 -7.12 -0.36 6.2e-12 Vitiligo; LIHC cis rs1256061 0.603 rs960069 chr14:64745002 C/T cg23250157 chr14:64679961 SYNE2 0.41 6.12 0.31 2.5e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.22 -0.45 3.11e-18 Electroencephalogram traits; LIHC cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg18252515 chr7:66147081 NA -1.27 -17.12 -0.68 6.98e-48 Diabetic kidney disease; LIHC cis rs1215050 0.791 rs1215054 chr4:98863009 T/G cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.61e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2303745 0.589 rs1965717 chr19:17398559 C/T cg04248312 chr19:17393744 ANKLE1 -0.73 -11.84 -0.54 2.43e-27 Systemic lupus erythematosus; LIHC cis rs10791097 0.667 rs12363163 chr11:130744509 A/G cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7523273 0.606 rs2488255 chr1:207941741 C/T cg22525895 chr1:207977042 MIR29B2 0.65 10.55 0.5 1.03e-22 Schizophrenia; LIHC cis rs11711311 0.955 rs12636536 chr3:113474226 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.9 -0.35 2.48e-11 IgG glycosylation; LIHC cis rs240764 0.782 rs239231 chr6:101105022 G/A cg09795085 chr6:101329169 ASCC3 0.53 7.46 0.37 7.07e-13 Neuroticism; LIHC cis rs9399135 0.967 rs952674 chr6:135349157 A/G cg22676075 chr6:135203613 NA 0.4 6.41 0.33 4.74e-10 Red blood cell count; LIHC cis rs2708977 0.965 rs2314109 chr2:97243532 A/G cg01950434 chr2:97203154 ARID5A -0.51 -7.73 -0.39 1.2e-13 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs57244997 0.725 rs67597312 chr6:162411023 A/G cg17173639 chr6:162384350 PARK2 -0.53 -6.96 -0.35 1.78e-11 Mosquito bite size; LIHC cis rs9303401 0.614 rs2240719 chr17:56582477 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.86 11.28 0.52 2.64e-25 Cognitive test performance; LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg13126279 chr21:47581558 C21orf56 0.47 7.72 0.39 1.32e-13 Testicular germ cell tumor; LIHC cis rs2303759 0.666 rs66967196 chr19:49808894 G/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.53 7.79 0.39 8.12e-14 Multiple sclerosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21939482 chr7:6388130 C7orf70 0.41 6.58 0.34 1.73e-10 Cognitive function; LIHC cis rs9814567 0.896 rs6763188 chr3:134349995 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.58 9.47 0.46 4.84e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs6912958 0.712 rs7746465 chr6:88348996 T/G cg23605328 chr1:201951606 RNPEP 0.38 6.07 0.31 3.35e-9 Monocyte percentage of white cells; LIHC cis rs4713118 0.586 rs6905516 chr6:28086478 A/G cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Parkinson's disease; LIHC cis rs11190604 0.767 rs4919459 chr10:102200371 C/T cg07080220 chr10:102295463 HIF1AN 0.48 6.86 0.35 3.23e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6952808 0.823 rs10950448 chr7:1966492 G/C cg20295408 chr7:1910781 MAD1L1 -0.46 -6.68 -0.34 9.99e-11 Bipolar disorder and schizophrenia; LIHC cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg16423285 chr20:60520624 NA -0.49 -8.1 -0.4 1.01e-14 Obesity-related traits; LIHC cis rs2274273 0.840 rs3742569 chr14:55818706 T/C cg01864836 chr14:55583639 NA -0.37 -6.58 -0.34 1.79e-10 Protein biomarker; LIHC cis rs9916302 0.904 rs602688 chr17:37439496 C/T cg07936489 chr17:37558343 FBXL20 -0.82 -13.42 -0.59 2.69e-33 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.871 rs55953412 chr11:68328283 C/T cg16797656 chr11:68205561 LRP5 0.5 7.73 0.39 1.25e-13 Total body bone mineral density; LIHC cis rs4819052 0.851 rs914218 chr21:46698445 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 11.83 0.54 2.59e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs208520 1.000 rs12212063 chr6:66985148 C/A cg07460842 chr6:66804631 NA 0.66 7.24 0.36 3.02e-12 Exhaled nitric oxide output; LIHC cis rs55665837 0.701 rs11023272 chr11:14630370 T/C cg16394018 chr11:14927549 NA 0.41 5.81 0.3 1.45e-8 Vitamin D levels; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg24846343 chr22:24311635 DDTL -0.61 -11.83 -0.54 2.74e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 10.0 0.48 8.11e-21 Platelet count; LIHC trans rs2727020 0.658 rs4980440 chr11:49386017 C/T cg15704280 chr7:45808275 SEPT13 -0.95 -19.19 -0.72 3.27e-56 Coronary artery disease; LIHC cis rs35146811 0.771 rs6465762 chr7:99620554 G/A cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.4 5.73 0.3 2.15e-8 Coronary artery disease; LIHC cis rs9814567 1.000 rs9289476 chr3:134237103 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2832191 0.692 rs2254872 chr21:30414724 C/T cg08807101 chr21:30365312 RNF160 0.8 12.34 0.56 3.46e-29 Dental caries; LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg06497051 chr1:156261200 TMEM79 0.37 6.0 0.31 5.1e-9 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7216064 0.655 rs8078543 chr17:66037251 G/T cg12091567 chr17:66097778 LOC651250 0.86 14.84 0.63 8.69e-39 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9325144 0.560 rs2013804 chr12:38631079 C/T cg26384229 chr12:38710491 ALG10B -0.49 -7.64 -0.38 2.24e-13 Morning vs. evening chronotype; LIHC cis rs780096 0.565 rs8179252 chr2:27746832 A/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.39 -5.91 -0.3 8.32e-9 Total body bone mineral density; LIHC trans rs61931739 0.517 rs7958755 chr12:34294699 T/C cg26384229 chr12:38710491 ALG10B 0.56 7.28 0.37 2.27e-12 Morning vs. evening chronotype; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.63 0.46 1.44e-19 Height; LIHC cis rs4665809 0.549 rs17527979 chr2:26428132 A/G cg04944784 chr2:26401820 FAM59B -0.64 -6.88 -0.35 2.84e-11 Gut microbiome composition (summer); LIHC cis rs708547 0.676 rs11133470 chr4:57864926 G/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.69 12.32 0.55 4e-29 Response to bleomycin (chromatid breaks); LIHC cis rs4665809 1.000 rs12469163 chr2:26283587 T/C cg27170947 chr2:26402098 FAM59B -0.63 -7.79 -0.39 8.3e-14 Gut microbiome composition (summer); LIHC cis rs9443645 0.901 rs10455356 chr6:79664748 T/C cg05283184 chr6:79620031 NA -0.34 -5.76 -0.3 1.91e-8 Intelligence (multi-trait analysis); LIHC cis rs853679 0.517 rs4713148 chr6:28115921 G/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs875971 0.800 rs427557 chr7:65519250 A/G cg11764359 chr7:65958608 NA 0.83 13.83 0.6 7.49e-35 Aortic root size; LIHC cis rs2295359 1.000 rs9729046 chr1:67607082 C/G cg12940439 chr1:67600707 NA 0.39 7.04 0.36 1.04e-11 Psoriasis; LIHC cis rs1707322 1.000 rs7539800 chr1:46262129 C/G cg03146154 chr1:46216737 IPP -0.47 -7.46 -0.37 7.01e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6089584 0.566 rs55881457 chr20:60608424 G/A cg06108461 chr20:60628389 TAF4 -0.65 -9.06 -0.44 1.03e-17 Body mass index; LIHC trans rs4843747 0.671 rs28451517 chr16:88109127 A/C cg26811252 chr16:29126840 RRN3P2 0.43 7.02 0.35 1.16e-11 Menopause (age at onset); LIHC cis rs7208859 0.623 rs8075163 chr17:29106310 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1552244 0.572 rs3774208 chr3:10164722 T/G cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs6754311 0.731 rs7579771 chr2:136580260 T/A cg15123519 chr2:136567270 LCT -0.46 -9.47 -0.46 4.86e-19 Mosquito bite size; LIHC cis rs61041384 0.661 rs4759407 chr12:123689674 C/T cg00376283 chr12:123451042 ABCB9 -0.55 -6.14 -0.32 2.28e-9 Schizophrenia; LIHC cis rs7703744 0.747 rs6896559 chr5:118678718 G/C cg10911160 chr5:118691794 TNFAIP8 -0.49 -5.79 -0.3 1.56e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2832191 1.000 rs2832189 chr21:30487414 C/T cg08807101 chr21:30365312 RNF160 -0.59 -9.28 -0.45 2.02e-18 Dental caries; LIHC cis rs7412746 0.611 rs11204726 chr1:150743492 T/C cg17724175 chr1:150552817 MCL1 0.46 9.16 0.44 4.94e-18 Melanoma; LIHC cis rs3806843 0.518 rs2563310 chr5:140015741 A/G cg19875535 chr5:140030758 IK -0.34 -5.73 -0.3 2.17e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9790314 0.586 rs16832246 chr3:161109916 A/G cg03342759 chr3:160939853 NMD3 0.53 8.01 0.4 1.79e-14 Morning vs. evening chronotype; LIHC cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg11645453 chr3:52864694 ITIH4 0.22 5.82 0.3 1.38e-8 Bipolar disorder; LIHC cis rs748404 0.511 rs12442190 chr15:43445305 T/C cg27015174 chr15:43622946 ADAL;LCMT2 -0.36 -5.81 -0.3 1.41e-8 Lung cancer; LIHC trans rs7246657 0.943 rs1035479 chr19:37893300 G/T cg10208301 chr11:6592745 DNHD1 -0.44 -6.35 -0.32 6.91e-10 Coronary artery calcification; LIHC cis rs8053891 0.673 rs10492825 chr16:72018417 T/C cg01557791 chr16:72042693 DHODH -0.5 -7.34 -0.37 1.53e-12 Coronary artery disease; LIHC cis rs10870270 0.956 rs10870281 chr10:133762642 G/A cg26149184 chr10:133730230 NA 0.47 7.49 0.38 5.75e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2439831 0.702 rs7175032 chr15:44060236 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.4 0.33 5.2e-10 Lung cancer in ever smokers; LIHC cis rs11098499 0.731 rs10015579 chr4:120271802 T/C cg09307838 chr4:120376055 NA 0.63 9.88 0.47 2.06e-20 Corneal astigmatism; LIHC cis rs10791097 0.720 rs6590516 chr11:130733393 G/T cg14779329 chr11:130786720 SNX19 0.38 5.8 0.3 1.54e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs13191362 1.000 rs34655790 chr6:163202739 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.81 6.79 0.34 4.99e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11122272 0.735 rs2790877 chr1:231535427 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.75e-22 Hemoglobin concentration; LIHC cis rs1144333 1.000 rs76192904 chr1:76359995 C/T cg22875332 chr1:76189707 ACADM 0.4 6.25 0.32 1.22e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs736408 0.812 rs746694 chr3:52826620 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.44 6.92 0.35 2.21e-11 Bipolar disorder; LIHC cis rs1355223 0.966 rs11602318 chr11:34766983 C/T cg11058730 chr11:34937778 PDHX;APIP 0.46 6.38 0.33 5.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs5769707 0.681 rs739236 chr22:50041602 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.25 -0.41 3.47e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.01 -0.44 1.43e-17 Bipolar disorder; LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs7903847 0.620 rs17112676 chr10:99122288 G/A cg20016023 chr10:99160130 RRP12 -0.41 -6.35 -0.32 7.01e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2439831 1.000 rs2245790 chr15:43744457 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.78 13.44 0.59 2.41e-33 Lung cancer in ever smokers; LIHC cis rs4665809 0.877 rs35224700 chr2:26298037 T/C cg04944784 chr2:26401820 FAM59B 0.62 6.75 0.34 6.3e-11 Gut microbiome composition (summer); LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg07157834 chr1:205819609 PM20D1 0.67 10.06 0.48 4.98e-21 Menarche (age at onset); LIHC cis rs2607426 1.000 rs13108 chr19:41271104 T/C cg20631044 chr19:41255890 C19orf54;SNRPA -0.47 -5.83 -0.3 1.3e-8 Blood protein levels; LIHC cis rs78062588 1.000 rs73001418 chr1:154585594 T/A cg24304309 chr1:154577895 ADAR -0.5 -5.86 -0.3 1.11e-8 Lung cancer; LIHC cis rs826838 0.967 rs11169169 chr12:39093153 A/C cg13010199 chr12:38710504 ALG10B 0.53 6.54 0.33 2.29e-10 Heart rate; LIHC cis rs6594499 0.500 rs10491424 chr5:110453806 T/C cg04022379 chr5:110408740 TSLP 0.56 9.2 0.45 3.7e-18 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1018836 0.828 rs4735236 chr8:91583909 A/G cg16814680 chr8:91681699 NA -0.56 -8.89 -0.43 3.46e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1198430 1.000 rs1198434 chr1:23758134 A/G cg19827787 chr1:23763612 ASAP3 0.36 6.11 0.31 2.69e-9 Total cholesterol levels; LIHC cis rs9916302 0.904 rs11869109 chr17:37518205 G/T cg00129232 chr17:37814104 STARD3 0.38 6.15 0.32 2.21e-9 Glomerular filtration rate (creatinine); LIHC cis rs2153535 0.580 rs4587214 chr6:8454119 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.67 0.42 1.82e-16 Motion sickness; LIHC trans rs7246657 0.943 rs7259968 chr19:37811854 T/C cg24637308 chr11:6592297 DNHD1 0.43 6.04 0.31 4.13e-9 Coronary artery calcification; LIHC cis rs17685 0.753 rs10233282 chr7:75790081 C/T cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.57e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg20607798 chr8:58055168 NA 0.63 7.94 0.39 2.86e-14 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.771 rs12205013 chr6:86333029 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.94 -0.39 2.96e-14 Response to antipsychotic treatment; LIHC cis rs4819052 0.851 rs2838850 chr21:46671445 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.76 0.54 4.69e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs796364 0.806 rs11688194 chr2:200916239 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs2439831 0.681 rs7175434 chr15:43628542 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.91 17.4 0.69 5.02e-49 Lung cancer in ever smokers; LIHC cis rs13108904 0.901 rs12509700 chr4:1296321 A/G cg20887711 chr4:1340912 KIAA1530 0.47 7.13 0.36 6.19e-12 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00319567 chr13:60971258 TDRD3 0.5 7.06 0.36 9.6e-12 Lung function (FEV1/FVC); LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.87 0.39 4.61e-14 Prudent dietary pattern; LIHC cis rs17102423 0.963 rs11626496 chr14:65600981 C/G cg11161011 chr14:65562177 MAX -0.44 -6.09 -0.31 3e-9 Obesity-related traits; LIHC cis rs10876993 0.893 rs3825078 chr12:58089413 A/T cg15848620 chr12:58087721 OS9 -0.55 -7.35 -0.37 1.46e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs1552244 0.751 rs12715665 chr3:10021601 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.95 0.47 1.22e-20 Alzheimer's disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg14819942 chr15:35414228 NA 0.48 6.6 0.34 1.6e-10 Hepatitis; LIHC cis rs12744310 1.000 rs12749636 chr1:41758446 A/G cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs1075232 0.655 rs28451043 chr15:31587562 A/T cg04373760 chr16:53404718 NA 0.65 6.23 0.32 1.38e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg24642844 chr7:1081250 C7orf50 -0.88 -8.49 -0.42 6.52e-16 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg07424592 chr7:64974309 NA 0.81 9.47 0.46 4.62e-19 Diabetic kidney disease; LIHC cis rs56011263 0.687 rs4690293 chr4:706101 A/G cg17689763 chr4:710664 PCGF3 -0.74 -10.82 -0.51 1.14e-23 White blood cell count; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.24 0.81 4.1e-80 Prudent dietary pattern; LIHC cis rs611744 0.870 rs650925 chr8:109196725 T/C cg18478394 chr8:109455254 TTC35 0.41 6.73 0.34 7.31e-11 Dupuytren's disease; LIHC cis rs11971779 0.793 rs11764426 chr7:139024050 C/G cg07862535 chr7:139043722 LUC7L2 0.67 11.5 0.53 4.27e-26 Diisocyanate-induced asthma; LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs2295359 0.824 rs4655679 chr1:67599657 A/G cg03340356 chr1:67600835 NA -0.4 -6.18 -0.32 1.8e-9 Psoriasis; LIHC cis rs7762018 0.655 rs11966349 chr6:170162537 A/G cg16283753 chr6:170068014 WDR27 0.45 5.99 0.31 5.46e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs4638749 0.677 rs7370742 chr2:108815385 T/C cg25838818 chr2:108905173 SULT1C2 -0.4 -7.0 -0.35 1.37e-11 Blood pressure; LIHC cis rs7552404 0.731 rs6699682 chr1:76340123 A/G cg03433033 chr1:76189801 ACADM -0.53 -6.49 -0.33 2.94e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1534166 0.601 rs13324779 chr3:133510413 G/A cg27366882 chr3:133540807 NA -0.43 -7.29 -0.37 2.18e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs72781680 0.566 rs72794293 chr2:23898149 A/G cg08917208 chr2:24149416 ATAD2B 0.63 6.14 0.31 2.33e-9 Lymphocyte counts; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11814935 chr1:202858358 RABIF -0.5 -7.31 -0.37 1.91e-12 Cognitive function; LIHC cis rs2731664 0.756 rs2545796 chr5:176864269 T/C cg23176889 chr5:176863531 GRK6 -0.7 -12.74 -0.57 1.12e-30 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.621 rs7394681 chr11:952111 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.07 0.48 4.62e-21 Alzheimer's disease (late onset); LIHC cis rs55665837 1.000 rs12288873 chr11:14450465 C/T cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg18590015 chr6:138745469 NHSL1 0.4 6.21 0.32 1.56e-9 Electroencephalogram traits; LIHC cis rs7116495 0.609 rs7111379 chr11:71826319 C/T cg10381502 chr11:71823885 C11orf51 1.06 9.3 0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs9649213 0.593 rs6465667 chr7:97957885 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.12e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs11122272 0.733 rs2749700 chr1:231522734 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs2242116 0.743 rs11719795 chr3:46951935 T/C cg27129171 chr3:47204927 SETD2 0.5 7.49 0.38 6.12e-13 Birth weight; LIHC cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg24101359 chr6:42928495 GNMT 0.43 5.87 0.3 1.04e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4689592 0.503 rs59640165 chr4:7051661 G/A cg06697600 chr4:7070879 GRPEL1 0.64 9.65 0.46 1.19e-19 Monocyte percentage of white cells; LIHC cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2404602 0.619 rs7342603 chr15:76982625 C/T cg03037974 chr15:76606532 NA 0.74 14.46 0.62 2.53e-37 Blood metabolite levels; LIHC cis rs801193 0.904 rs4718403 chr7:66242729 C/G cg18876405 chr7:65276391 NA 0.43 7.4 0.37 1.06e-12 Aortic root size; LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg20822365 chr15:83621694 HOMER2 0.41 6.05 0.31 3.8e-9 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs1707322 0.964 rs785509 chr1:46527300 G/A cg06784218 chr1:46089804 CCDC17 -0.38 -6.96 -0.35 1.71e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03147627 chr4:83956202 COPS4 0.44 6.2 0.32 1.59e-9 Pancreatic cancer; LIHC cis rs7789940 1.000 rs2072435 chr7:75959188 G/A cg10167463 chr7:75959203 YWHAG -0.45 -7.15 -0.36 5.2e-12 Multiple sclerosis; LIHC cis rs7212590 0.655 rs56198517 chr17:57976582 G/T cg10252138 chr17:58120427 NA -0.62 -6.64 -0.34 1.23e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs9325144 0.560 rs7980635 chr12:38668355 G/T cg26384229 chr12:38710491 ALG10B -0.59 -8.07 -0.4 1.19e-14 Morning vs. evening chronotype; LIHC trans rs4824093 0.610 rs12106611 chr22:50242686 G/A cg09872104 chr7:134855509 C7orf49 -0.74 -6.08 -0.31 3.19e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs7095607 0.606 rs10998011 chr10:69958623 A/G cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.66e-9 Lung function (FVC); LIHC cis rs1707322 0.964 rs785496 chr1:46588006 T/C cg06784218 chr1:46089804 CCDC17 -0.4 -7.22 -0.36 3.38e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1691799 0.867 rs1168348 chr12:66757168 G/A cg16791601 chr12:66731901 HELB -0.55 -13.16 -0.58 2.77e-32 White blood cell count (basophil); LIHC cis rs9948 1.000 rs2276654 chr2:97492479 G/A cg01990225 chr2:97406019 LMAN2L -0.66 -6.24 -0.32 1.32e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1506636 1.000 rs2429616 chr7:123406034 C/T cg03229431 chr7:123269106 ASB15 0.6 11.92 0.54 1.25e-27 Plateletcrit;Platelet count; LIHC cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg16497277 chr3:49208875 KLHDC8B 0.47 5.98 0.31 5.67e-9 Menarche (age at onset); LIHC cis rs2273669 0.667 rs111523655 chr6:109301664 G/A cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs7131987 0.622 rs7294598 chr12:29531989 A/C cg21522988 chr12:29376872 FAR2 -0.26 -5.9 -0.3 8.71e-9 QT interval; LIHC cis rs769267 0.930 rs4808957 chr19:19567248 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.93 0.39 3.07e-14 Tonsillectomy; LIHC cis rs240764 0.817 rs240154 chr6:101065792 G/T cg09795085 chr6:101329169 ASCC3 0.48 6.65 0.34 1.18e-10 Neuroticism; LIHC cis rs61990749 0.597 rs176944 chr14:78176211 G/T cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.8 0.39 7.44e-14 Fibroblast growth factor basic levels; LIHC cis rs11800820 0.557 rs55881259 chr1:246665951 C/T cg16700716 chr1:246684329 NA 0.48 8.1 0.4 9.84e-15 Obesity-related traits; LIHC cis rs7223966 1.000 rs6504169 chr17:61709145 A/G cg05941027 chr17:61774174 LIMD2 0.34 6.92 0.35 2.2e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7238033 0.620 rs11082469 chr18:43321269 A/G cg20610511 chr18:43302872 SLC14A1 0.37 6.15 0.32 2.17e-9 Bladder cancer; LIHC cis rs10508774 1.000 rs72795572 chr10:32909986 G/T cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7208859 0.623 rs3752021 chr17:29111043 G/C cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4919087 0.962 rs10748691 chr10:98983955 C/T cg25902810 chr10:99078978 FRAT1 0.71 10.26 0.49 1.01e-21 Monocyte count; LIHC cis rs910316 0.699 rs175039 chr14:75468950 G/C cg11812906 chr14:75593930 NEK9 -0.74 -13.63 -0.59 4.25e-34 Height; LIHC trans rs1814175 0.781 rs1851872 chr11:50009770 A/G cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs769267 0.929 rs34538000 chr19:19481379 G/T cg03709012 chr19:19516395 GATAD2A -1.01 -18.1 -0.7 7.56e-52 Tonsillectomy; LIHC cis rs12048904 0.541 rs6699536 chr1:101276544 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.65 10.25 0.48 1.12e-21 Multiple sclerosis; LIHC cis rs11628318 0.614 rs1190335 chr14:103111358 T/C cg01864069 chr14:103024347 NA -0.35 -5.9 -0.3 8.57e-9 Platelet count; LIHC cis rs8067354 0.830 rs57510610 chr17:57889406 T/A cg02344993 chr17:57696989 CLTC 0.58 9.4 0.45 7.78e-19 Hemoglobin concentration; LIHC cis rs2439831 0.702 rs3784275 chr15:44091386 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.54 6.42 0.33 4.67e-10 Lung cancer in ever smokers; LIHC cis rs1075232 1.000 rs12439239 chr15:31651718 G/A cg01030201 chr15:31746330 NA -0.78 -6.11 -0.31 2.66e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs6582630 0.519 rs80226845 chr12:38528231 C/A cg26384229 chr12:38710491 ALG10B 0.68 9.64 0.46 1.26e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs9549367 0.713 rs9549352 chr13:113833221 A/G cg18105134 chr13:113819100 PROZ -0.8 -13.6 -0.59 5.71e-34 Platelet distribution width; LIHC cis rs4891159 0.548 rs690082 chr18:74116668 C/T cg24786174 chr18:74118243 ZNF516 0.85 17.39 0.68 5.72e-49 Longevity; LIHC cis rs3204270 0.810 rs8077959 chr17:79670122 G/A cg18367735 chr17:79674897 NA 0.73 8.5 0.42 6.14e-16 Dental caries; LIHC trans rs877282 0.853 rs11595510 chr10:756757 C/G cg22713356 chr15:30763199 NA 1.2 11.07 0.51 1.45e-24 Uric acid levels; LIHC cis rs924607 0.900 rs1697950 chr5:616890 G/A cg04221910 chr5:616842 CEP72 -0.42 -7.45 -0.37 7.47e-13 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg08392591 chr16:89556376 ANKRD11 0.51 8.24 0.41 3.83e-15 Multiple myeloma (IgH translocation); LIHC cis rs10193935 0.901 rs13384404 chr2:42601147 G/T cg27598129 chr2:42591480 NA -0.72 -11.42 -0.53 8.13e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs61677309 0.964 rs112753655 chr11:118154795 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs7044106 0.791 rs10984998 chr9:123481516 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.11 0.52 1.07e-24 Hip circumference adjusted for BMI; LIHC cis rs763121 0.853 rs5757234 chr22:39072686 C/T cg21395723 chr22:39101663 GTPBP1 0.41 6.94 0.35 1.98e-11 Menopause (age at onset); LIHC cis rs240764 0.697 rs370757 chr6:101134156 T/C cg09795085 chr6:101329169 ASCC3 0.45 6.16 0.32 2.01e-9 Neuroticism; LIHC cis rs7100689 0.753 rs1572816 chr10:82137600 A/G cg01528321 chr10:82214614 TSPAN14 0.9 12.36 0.56 2.98e-29 Post bronchodilator FEV1; LIHC cis rs12479064 0.724 rs3792143 chr2:100057020 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -7.68 -0.38 1.65e-13 Chronic sinus infection; LIHC cis rs13217239 0.646 rs10456352 chr6:26990358 A/T cg12292205 chr6:26970375 C6orf41 0.45 7.77 0.39 9.2e-14 Schizophrenia; LIHC cis rs1008375 0.966 rs6449313 chr4:17588320 A/G cg16339924 chr4:17578868 LAP3 0.56 7.44 0.37 8.46e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs26868 0.742 rs26848 chr16:2263516 A/G cg25665528 chr16:2260870 C16orf79 -0.47 -9.63 -0.46 1.42e-19 Height; LIHC cis rs2153535 0.580 rs9405390 chr6:8466209 T/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg09323728 chr8:95962352 TP53INP1 -0.3 -6.47 -0.33 3.3e-10 Type 2 diabetes; LIHC cis rs2749592 0.550 rs7081464 chr10:37883937 C/T cg25427524 chr10:38739819 LOC399744 0.57 10.29 0.49 7.98e-22 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs1814175 0.586 rs10769603 chr11:49688837 T/C cg15704280 chr7:45808275 SEPT13 -0.93 -18.22 -0.7 2.47e-52 Height; LIHC cis rs3099143 1.000 rs4886831 chr15:77106801 T/C cg21673338 chr15:77095150 SCAPER 0.48 7.39 0.37 1.11e-12 Recalcitrant atopic dermatitis; LIHC cis rs17152411 0.895 rs7906592 chr10:126627861 C/G cg07906193 chr10:126599966 NA 0.47 7.31 0.37 1.93e-12 Height; LIHC cis rs17253792 0.822 rs76192881 chr14:56034654 C/T cg01858014 chr14:56050164 KTN1 -0.72 -7.0 -0.35 1.36e-11 Putamen volume; LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg00656387 chr3:40428638 ENTPD3 0.51 8.67 0.42 1.82e-16 Renal cell carcinoma; LIHC cis rs9467773 1.000 rs1884949 chr6:26568067 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.75 0.6 1.5e-34 Intelligence (multi-trait analysis); LIHC cis rs2380220 0.872 rs67846436 chr6:95951521 G/T cg04719120 chr6:96025338 MANEA -0.59 -6.21 -0.32 1.54e-9 Behavioural disinhibition (generation interaction); LIHC cis rs4908768 0.520 rs6681362 chr1:8658527 T/G cg20416874 chr1:8611966 RERE -0.63 -11.71 -0.53 7.32e-27 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7659604 0.643 rs6838881 chr4:122663616 A/T cg19748678 chr4:122722346 EXOSC9 0.43 6.51 0.33 2.6200000000000003e-10 Type 2 diabetes; LIHC cis rs992157 0.697 rs13384682 chr2:219069137 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.79 13.33 0.58 6.25e-33 Colorectal cancer; LIHC cis rs9430161 0.611 rs12081181 chr1:11034165 T/G cg27631724 chr1:11040367 C1orf127 0.36 6.48 0.33 3.18e-10 Ewing sarcoma; LIHC cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg12310025 chr6:25882481 NA 0.56 7.58 0.38 3.27e-13 Blood metabolite levels; LIHC cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg22618164 chr12:122356400 WDR66 0.57 8.34 0.41 1.84e-15 Mean corpuscular volume; LIHC cis rs7106204 1.000 rs6484025 chr11:24214514 C/G ch.11.24196551F chr11:24239977 NA 0.67 6.69 0.34 9.15e-11 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2635047 0.935 rs2576031 chr18:44658146 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.47 6.21 0.32 1.54e-9 Educational attainment; LIHC cis rs903552 0.866 rs11247296 chr15:102007919 T/C cg06707286 chr15:102010195 PCSK6 -0.51 -7.47 -0.37 6.81e-13 Diabetic kidney disease; LIHC cis rs876084 0.505 rs7840588 chr8:121108256 G/T cg06265175 chr8:121136014 COL14A1 0.48 7.72 0.39 1.34e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6582630 0.519 rs8189623 chr12:38351436 G/A cg26384229 chr12:38710491 ALG10B 0.6 8.25 0.41 3.42e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs710216 0.917 rs4660691 chr1:43417150 T/G cg03128534 chr1:43423976 SLC2A1 -0.48 -6.04 -0.31 4.12e-9 Red cell distribution width; LIHC cis rs7408868 1.000 rs10407320 chr19:15275716 G/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.89 -0.3 9.39e-9 Pulse pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08400120 chr3:169940839 PRKCI 0.45 6.3 0.32 9.07e-10 Pancreatic cancer; LIHC cis rs1577917 0.740 rs7775864 chr6:86247759 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.66 0.34 1.12e-10 Response to antipsychotic treatment; LIHC trans rs7246657 1.000 rs7247672 chr19:37743928 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.19 0.32 1.7e-9 Coronary artery calcification; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg26338869 chr17:61819248 STRADA 0.59 8.75 0.43 9.61e-17 Prudent dietary pattern; LIHC cis rs959260 0.528 rs9909443 chr17:73308346 C/T cg14668889 chr17:73230827 NUP85 0.54 5.88 0.3 9.83e-9 Systemic lupus erythematosus; LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg14893161 chr1:205819251 PM20D1 0.81 11.77 0.54 4.57e-27 Menarche (age at onset); LIHC cis rs4450131 0.897 rs10901796 chr10:126335586 T/C cg20435097 chr10:126320824 FAM53B -0.51 -9.37 -0.45 9.77e-19 White blood cell count (basophil); LIHC trans rs3960554 0.740 rs10216079 chr7:75690988 A/C cg19862616 chr7:65841803 NCRNA00174 0.6 8.41 0.41 1.13e-15 Eotaxin levels; LIHC cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg20090690 chr10:134436459 INPP5A 0.44 5.74 0.3 2.12e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg06634786 chr22:41940651 POLR3H -0.78 -8.55 -0.42 4.1e-16 Vitiligo; LIHC cis rs8067545 0.611 rs77449863 chr17:20191860 C/G cg13482628 chr17:19912719 NA -0.41 -6.77 -0.34 5.62e-11 Schizophrenia; LIHC cis rs796364 0.806 rs11689664 chr2:201099961 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.64 -7.02 -0.36 1.17e-11 Schizophrenia; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg27432699 chr2:27873401 GPN1 -0.52 -7.38 -0.37 1.22e-12 Total body bone mineral density; LIHC cis rs2180341 0.781 rs6913350 chr6:127570560 C/T cg27446573 chr6:127587934 RNF146 0.65 10.01 0.48 7.65e-21 Breast cancer; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg09224379 chr16:11052486 CLEC16A 0.37 6.38 0.33 5.62e-10 Alopecia areata; LIHC cis rs11077998 0.901 rs4789798 chr17:80531643 C/G cg10255544 chr17:80519551 FOXK2 0.48 8.53 0.42 4.96e-16 Reticulocyte fraction of red cells; LIHC cis rs16958440 0.867 rs61689863 chr18:44669157 A/T cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg11890956 chr21:40555474 PSMG1 -0.49 -8.21 -0.41 4.68e-15 Menarche (age at onset); LIHC cis rs12477438 0.520 rs1453563 chr2:99720267 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.19 0.61 3.03e-36 Chronic sinus infection; LIHC cis rs34779708 0.931 rs10437420 chr10:35335044 A/C cg03585969 chr10:35415529 CREM -0.78 -11.72 -0.54 6.62e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3823572 0.542 rs10271889 chr7:133635846 A/G cg03336402 chr7:133662267 EXOC4 0.47 5.84 0.3 1.22e-8 Intelligence (multi-trait analysis); LIHC cis rs58688157 0.739 rs56333810 chr11:575408 C/G cg16486109 chr11:613632 IRF7 0.57 5.75 0.3 1.93e-8 Systemic lupus erythematosus; LIHC cis rs11583043 0.957 rs6577223 chr1:101499750 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.67 0.42 1.71e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg16822855 chr3:40428330 ENTPD3 0.33 5.96 0.31 6.36e-9 Renal cell carcinoma; LIHC cis rs1892700 1.000 rs4816463 chr21:34999978 C/T cg14850771 chr21:34775459 IFNGR2 -0.45 -6.03 -0.31 4.2e-9 Educational attainment; LIHC cis rs1949733 1.000 rs1880023 chr4:8480831 C/T cg11789530 chr4:8429930 ACOX3 -0.8 -11.74 -0.54 5.8e-27 Response to antineoplastic agents; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20414838 chr1:53704138 MAGOH -0.48 -6.11 -0.31 2.78e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3008870 1.000 rs2815371 chr1:67504313 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.97 16.79 0.67 1.46e-46 Lymphocyte percentage of white cells; LIHC cis rs7086627 0.515 rs11202959 chr10:82209672 A/G cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC cis rs2637266 0.935 rs7918777 chr10:78394375 A/G cg18941641 chr10:78392320 NA 0.29 6.4 0.33 5.23e-10 Pulmonary function; LIHC cis rs12701220 0.541 rs12535516 chr7:1114440 C/G cg02733842 chr7:1102375 C7orf50 -0.69 -7.62 -0.38 2.55e-13 Bronchopulmonary dysplasia; LIHC cis rs9858542 0.953 rs7633271 chr3:49555963 T/C cg03060546 chr3:49711283 APEH -0.47 -6.45 -0.33 3.8e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg23404012 chr14:71066865 MED6 0.36 6.71 0.34 8.31e-11 Calcium levels; LIHC cis rs2576037 0.526 rs4890703 chr18:44522037 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.52 -7.52 -0.38 4.76e-13 Personality dimensions; LIHC cis rs7223966 1.000 rs7223672 chr17:61720565 T/C cg05941027 chr17:61774174 LIMD2 0.34 6.92 0.35 2.2e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2806561 0.765 rs1757046 chr1:23511821 T/C cg12483005 chr1:23474871 LUZP1 0.43 6.72 0.34 7.84e-11 Height; LIHC cis rs4638749 0.677 rs12475343 chr2:108851373 T/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.79 -0.34 4.93e-11 Blood pressure; LIHC cis rs10751667 0.666 rs10902249 chr11:958566 C/T ch.11.42038R chr11:967971 AP2A2 -0.56 -10.07 -0.48 4.52e-21 Alzheimer's disease (late onset); LIHC cis rs4332037 0.851 rs1403175 chr7:1964357 A/T cg23422044 chr7:1970798 MAD1L1 0.62 7.15 0.36 5.45e-12 Bipolar disorder; LIHC cis rs4631830 0.900 rs10763588 chr10:51539762 G/T cg20129853 chr10:51489980 NA -0.4 -8.62 -0.42 2.59e-16 Prostate-specific antigen levels; LIHC cis rs1419980 0.730 rs11054897 chr12:7774251 A/G cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC trans rs561341 0.941 rs112569713 chr17:30271738 C/T cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 7.74e-24 Hip circumference adjusted for BMI; LIHC trans rs7618501 1.000 rs6802890 chr3:49832261 A/G cg21659725 chr3:3221576 CRBN 0.97 18.83 0.71 9.25e-55 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg10802521 chr3:52805072 NEK4 -0.43 -7.22 -0.36 3.34e-12 Bipolar disorder; LIHC cis rs916888 0.821 rs415430 chr17:44859144 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs875971 1.000 rs12532998 chr7:65967459 A/C cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.64e-11 Aortic root size; LIHC cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg09060608 chr5:178986726 RUFY1 0.37 5.73 0.3 2.25e-8 Lung cancer; LIHC cis rs4474465 0.790 rs4945293 chr11:78254554 T/C cg27205649 chr11:78285834 NARS2 0.39 5.92 0.3 7.82e-9 Alzheimer's disease (survival time); LIHC cis rs6582630 0.679 rs10785514 chr12:38573689 T/C cg26384229 chr12:38710491 ALG10B 0.42 6.4 0.33 4.98e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs12478296 1.000 rs55732177 chr2:243040006 C/T cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.1e-27 Obesity-related traits; LIHC cis rs7618501 0.633 rs4688757 chr3:50035323 T/C cg24110177 chr3:50126178 RBM5 -0.48 -7.72 -0.39 1.29e-13 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.904 rs55660616 chr17:37684990 C/A cg03013999 chr17:37608204 MED1 0.35 5.78 0.3 1.71e-8 Glomerular filtration rate (creatinine); LIHC cis rs1555322 0.530 rs6060341 chr20:33863633 C/T cg08210727 chr20:33865349 NA -0.51 -5.91 -0.3 8.36e-9 Attention deficit hyperactivity disorder; LIHC cis rs4665809 1.000 rs1560868 chr2:26281459 A/T cg04944784 chr2:26401820 FAM59B 0.66 8.61 0.42 2.8e-16 Gut microbiome composition (summer); LIHC cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.67 11.31 0.52 2.1e-25 Menarche (age at onset); LIHC cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg16497277 chr3:49208875 KLHDC8B -0.51 -6.42 -0.33 4.56e-10 Menarche (age at onset); LIHC cis rs1005277 0.540 rs1814077 chr10:37992018 G/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.5 -0.46 3.8e-19 Extrinsic epigenetic age acceleration; LIHC cis rs250677 1.000 rs28173 chr5:148423573 C/T cg18129178 chr5:148520854 ABLIM3 -0.43 -7.02 -0.35 1.22e-11 Breast cancer; LIHC trans rs877282 0.853 rs12763400 chr10:763617 C/T cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs7617773 0.710 rs36064160 chr3:48243101 C/G cg11946769 chr3:48343235 NME6 0.89 11.05 0.51 1.79e-24 Coronary artery disease; LIHC cis rs57590327 0.503 rs6800295 chr3:81593011 A/G cg07356753 chr3:81810745 GBE1 -0.54 -8.18 -0.4 5.73e-15 Extraversion; LIHC cis rs3008870 0.755 rs4655660 chr1:67402953 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.77 0.5 1.73e-23 Lymphocyte percentage of white cells; LIHC cis rs9916302 0.904 rs11867312 chr17:37597748 C/T cg00129232 chr17:37814104 STARD3 -0.4 -6.43 -0.33 4.4e-10 Glomerular filtration rate (creatinine); LIHC cis rs908922 0.627 rs1053588 chr1:152488063 C/T cg20991723 chr1:152506922 NA 0.51 8.71 0.43 1.29e-16 Hair morphology; LIHC cis rs9649213 0.593 rs6465683 chr7:98026092 C/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.82 -0.3 1.36e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs175714 0.845 rs175706 chr14:75976200 G/A cg01624173 chr14:75981868 NA 0.64 10.66 0.5 4.14e-23 Lymphocyte counts; LIHC cis rs11711311 1.000 rs7622515 chr3:113472538 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.26 -0.37 2.56e-12 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06444125 chr16:30103218 TBX6 -0.4 -6.06 -0.31 3.55e-9 Pancreatic cancer; LIHC cis rs1577917 0.771 rs2783171 chr6:86382765 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.64 12.59 0.56 4.13e-30 Response to antipsychotic treatment; LIHC cis rs875971 0.929 rs12673810 chr7:65923853 T/A cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs3741404 0.825 rs7111753 chr11:63942189 A/G cg24431193 chr11:63883947 FLRT1;MACROD1 -0.37 -5.75 -0.3 1.95e-8 Platelet count; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.95 0.63 3.03e-39 Prudent dietary pattern; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20197516 chr17:80373348 C17orf101 0.41 6.22 0.32 1.47e-9 Longevity; LIHC cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg11890956 chr21:40555474 PSMG1 1.02 14.54 0.62 1.3e-37 Cognitive function; LIHC cis rs7095607 0.693 rs7896727 chr10:69952376 C/T cg18986048 chr10:69913749 MYPN 0.43 6.53 0.33 2.36e-10 Lung function (FVC); LIHC cis rs1707322 0.686 rs2230658 chr1:46078854 A/G cg06784218 chr1:46089804 CCDC17 -0.42 -7.72 -0.39 1.3e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC cis rs611744 0.573 rs674580 chr8:109251690 C/G cg18478394 chr8:109455254 TTC35 0.38 6.54 0.33 2.25e-10 Dupuytren's disease; LIHC cis rs3018712 0.532 rs2513294 chr11:68421194 C/T cg16797656 chr11:68205561 LRP5 -0.44 -5.81 -0.3 1.44e-8 Total body bone mineral density; LIHC cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg22105103 chr4:187893119 NA 0.35 8.74 0.43 1.09e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs9420 1.000 rs543725 chr11:57483039 A/T cg19752551 chr11:57585705 CTNND1 -0.51 -7.25 -0.37 2.72e-12 Schizophrenia; LIHC cis rs778371 0.723 rs1078323 chr2:233681512 T/G cg08000102 chr2:233561755 GIGYF2 -0.74 -9.12 -0.44 6.34e-18 Schizophrenia; LIHC cis rs2455799 0.573 rs2174172 chr3:15768579 C/A cg12698662 chr3:15914712 MIR563 -0.39 -7.21 -0.36 3.62e-12 Mean platelet volume; LIHC cis rs1707322 1.000 rs6682683 chr1:46342337 A/G cg03146154 chr1:46216737 IPP 0.47 7.73 0.39 1.22e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg05564831 chr3:52568323 NT5DC2 0.37 5.91 0.3 8.25e-9 Bipolar disorder; LIHC cis rs908922 0.924 rs6669608 chr1:152475233 A/G cg20991723 chr1:152506922 NA 0.38 5.81 0.3 1.42e-8 Hair morphology; LIHC cis rs2075371 0.796 rs1643040 chr7:134011703 G/C cg11752832 chr7:134001865 SLC35B4 0.4 6.22 0.32 1.45e-9 Mean platelet volume; LIHC trans rs634534 0.561 rs14157 chr11:65769780 T/G cg17712092 chr4:129076599 LARP1B 0.74 13.06 0.58 6.53e-32 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.38 -0.45 9.67e-19 Bipolar disorder; LIHC cis rs3106136 0.843 rs6532479 chr4:95259235 C/A cg11021082 chr4:95130006 SMARCAD1 0.41 7.33 0.37 1.66e-12 Capecitabine sensitivity; LIHC cis rs1000083 0.915 rs1820160 chr5:96609774 T/C ch.5.96698337R chr5:96672581 NA 0.95 7.69 0.38 1.55e-13 Cisplatin-induced ototoxicity; LIHC cis rs3780378 0.875 rs2031906 chr9:5087495 C/T cg02405213 chr9:5042618 JAK2 -0.5 -8.54 -0.42 4.54e-16 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs11626933 0.959 rs17799226 chr14:90754538 C/T cg07150772 chr14:90864620 CALM1 -0.42 -5.88 -0.3 9.62e-9 Gut microbiota (bacterial taxa); LIHC cis rs2439831 0.850 rs2228368 chr15:44102010 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.38 0.33 5.66e-10 Lung cancer in ever smokers; LIHC cis rs1008375 0.898 rs2079892 chr4:17577163 G/A cg16339924 chr4:17578868 LAP3 0.45 6.22 0.32 1.44e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs600806 0.778 rs10776698 chr1:110013630 C/T cg10127483 chr1:110009974 SYPL2 0.49 6.34 0.32 7.25e-10 Intelligence (multi-trait analysis); LIHC trans rs208520 0.802 rs1342959 chr6:66883329 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.14 -0.4 7.54e-15 Exhaled nitric oxide output; LIHC cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg26119090 chr2:26468346 HADHA;HADHB 1.16 17.97 0.7 2.69e-51 Gut microbiome composition (summer); LIHC cis rs9902453 0.845 rs7218113 chr17:28372130 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs208520 0.690 rs176289 chr6:66766522 C/T cg07460842 chr6:66804631 NA -0.81 -9.21 -0.45 3.34e-18 Exhaled nitric oxide output; LIHC cis rs6964587 0.967 rs10953065 chr7:91808915 A/G cg17063962 chr7:91808500 NA -0.99 -18.44 -0.71 3.31e-53 Breast cancer; LIHC cis rs79149102 0.579 rs12591175 chr15:75356073 C/T cg16226627 chr15:75307476 SCAMP5 0.51 8.81 0.43 6.34e-17 Lung cancer; LIHC trans rs4819388 0.915 rs7278940 chr21:45648992 C/T cg17383793 chr5:52405638 MOCS2 -0.4 -6.31 -0.32 8.81e-10 Celiac disease; LIHC cis rs7833790 0.700 rs28390260 chr8:82769175 A/T cg02079420 chr8:82753780 SNX16 -0.36 -6.64 -0.34 1.21e-10 Diastolic blood pressure; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg10854029 chr8:22926554 TNFRSF10B -0.63 -7.23 -0.36 3.21e-12 Preeclampsia; LIHC cis rs35883536 0.647 rs2783696 chr1:101044089 G/A cg14515779 chr1:101123966 NA -0.48 -6.95 -0.35 1.83e-11 Monocyte count; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg26338869 chr17:61819248 STRADA 0.59 8.75 0.43 9.61e-17 Prudent dietary pattern; LIHC cis rs4845459 0.967 rs6701307 chr1:152590444 G/A cg20634798 chr1:152595351 LCE3A -0.31 -6.13 -0.31 2.46e-9 Psoriasis; LIHC cis rs2153535 0.580 rs1119688 chr6:8460850 T/C cg23788917 chr6:8435910 SLC35B3 0.62 8.75 0.43 1.01e-16 Motion sickness; LIHC cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.11 -0.55 2.53e-28 Alzheimer's disease; LIHC cis rs926392 0.666 rs56877916 chr20:37696192 A/T cg16355469 chr20:37678765 NA 0.48 6.99 0.35 1.43e-11 Dialysis-related mortality; LIHC cis rs7131987 0.621 rs3782506 chr12:29445422 A/C cg05697976 chr12:29376483 FAR2 -0.3 -6.11 -0.31 2.75e-9 QT interval; LIHC cis rs7613875 0.580 rs2624819 chr3:50010571 G/T cg21467203 chr3:49911342 NA -0.55 -10.33 -0.49 6.04e-22 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00371891 chr19:4723959 DPP9 0.43 6.34 0.32 7.38e-10 Pancreatic cancer; LIHC cis rs6860806 0.507 rs2631371 chr5:131703691 G/A cg24060327 chr5:131705240 SLC22A5 0.8 12.48 0.56 1.04e-29 Breast cancer; LIHC cis rs7772486 0.754 rs702318 chr6:146005873 G/T cg23711669 chr6:146136114 FBXO30 -0.71 -11.72 -0.54 6.49e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs7659604 0.628 rs6838153 chr4:122720999 A/G cg20573242 chr4:122745356 CCNA2 0.53 7.77 0.39 9.51e-14 Type 2 diabetes; LIHC cis rs10751667 0.666 rs7105477 chr11:964271 C/G cg06064525 chr11:970664 AP2A2 -0.56 -15.01 -0.63 1.72e-39 Alzheimer's disease (late onset); LIHC cis rs1008375 0.932 rs4698626 chr4:17605821 G/C cg02297831 chr4:17616191 MED28 0.44 6.81 0.35 4.51e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11864453 0.647 rs3764311 chr16:72125617 C/G cg01557791 chr16:72042693 DHODH -0.42 -6.97 -0.35 1.63e-11 Fibrinogen levels; LIHC cis rs9326248 0.817 rs6589598 chr11:117002403 A/G cg11861562 chr11:117069780 TAGLN 0.37 5.83 0.3 1.27e-8 Blood protein levels; LIHC cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.68 0.38 1.72e-13 Bipolar disorder; LIHC cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg23758822 chr17:41437982 NA 0.94 17.82 0.69 1.05e-50 Menopause (age at onset); LIHC cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg10802521 chr3:52805072 NEK4 -0.44 -7.19 -0.36 4.16e-12 Bipolar disorder; LIHC cis rs1401999 0.690 rs3805112 chr3:183645662 C/T cg01324343 chr3:183735012 ABCC5 0.53 8.57 0.42 3.56e-16 Anterior chamber depth; LIHC cis rs6918586 0.658 rs198829 chr6:26118893 A/G cg18357526 chr6:26021779 HIST1H4A -0.57 -8.41 -0.41 1.15e-15 Schizophrenia; LIHC cis rs8077889 0.917 rs28694735 chr17:41912144 A/G cg26893861 chr17:41843967 DUSP3 0.91 10.34 0.49 5.39e-22 Triglycerides; LIHC trans rs6733379 0.588 rs2193790 chr2:34445953 A/G cg05020625 chr6:43252858 TTBK1 0.23 6.27 0.32 1.08e-9 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg24209194 chr3:40518798 ZNF619 0.64 9.71 0.46 7.46e-20 Renal cell carcinoma; LIHC trans rs9926296 0.618 rs8058179 chr16:89846987 C/T cg20327061 chr1:6640478 ZBTB48 -0.52 -6.19 -0.32 1.73e-9 Vitiligo; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg24924221 chr8:22856702 RHOBTB2 0.62 6.13 0.31 2.43e-9 Musician's dystonia; LIHC cis rs2361718 0.933 rs8077849 chr17:78104137 C/T cg09238746 chr17:78121135 EIF4A3 -0.48 -7.2 -0.36 3.86e-12 Yeast infection; LIHC trans rs2727020 0.521 rs11040408 chr11:49534880 A/T cg15704280 chr7:45808275 SEPT13 0.78 11.76 0.54 4.71e-27 Coronary artery disease; LIHC cis rs7107174 1.000 rs1006441 chr11:77932126 G/C cg02023728 chr11:77925099 USP35 0.49 9.04 0.44 1.18e-17 Testicular germ cell tumor; LIHC trans rs1552244 0.515 rs111560858 chr3:10166845 G/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs7618501 0.735 rs9876508 chr3:49780844 G/A cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC cis rs875971 0.706 rs1643374 chr7:65872682 T/A cg14393609 chr7:65229607 NA 0.38 5.71 0.3 2.41e-8 Aortic root size; LIHC cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg05590025 chr7:65112418 INTS4L2 -0.6 -6.77 -0.34 5.69e-11 Diabetic kidney disease; LIHC cis rs5769765 1.000 rs2092982 chr22:50282204 C/A cg26441486 chr22:50317300 CRELD2 -0.35 -6.32 -0.32 7.96e-10 Schizophrenia; LIHC cis rs8060686 0.641 rs12448677 chr16:68209741 G/A cg05110241 chr16:68378359 PRMT7 -0.57 -6.52 -0.33 2.47e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs9611565 0.512 rs5996063 chr22:42168767 G/A cg03806693 chr22:41940476 POLR3H 0.97 10.19 0.48 1.76e-21 Vitiligo; LIHC cis rs10751667 0.560 rs10902267 chr11:1007831 T/C cg10932868 chr11:921992 NA 0.34 6.3 0.32 9.29e-10 Alzheimer's disease (late onset); LIHC cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg05890377 chr2:74357713 NA 0.63 12.87 0.57 3.55e-31 Gestational age at birth (maternal effect); LIHC cis rs12824058 0.831 rs4759450 chr12:130812732 G/A cg26677194 chr12:130822605 PIWIL1 0.51 7.25 0.36 2.88e-12 Menopause (age at onset); LIHC cis rs4819052 1.000 rs3746980 chr21:46711580 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 10.13 0.48 2.85e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6089584 1.000 rs6089591 chr20:60570548 A/C cg12751644 chr20:60527061 NA -0.37 -6.27 -0.32 1.09e-9 Body mass index; LIHC cis rs853679 0.517 rs4713144 chr6:28106790 C/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs7772486 0.686 rs9485019 chr6:146046381 C/G cg13319975 chr6:146136371 FBXO30 0.35 5.86 0.3 1.11e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs801193 1.000 rs7789184 chr7:66210195 A/T cg18876405 chr7:65276391 NA 0.42 7.32 0.37 1.79e-12 Aortic root size; LIHC cis rs79149102 0.579 rs74023908 chr15:75310710 T/C cg17294928 chr15:75287854 SCAMP5 -0.48 -6.26 -0.32 1.15e-9 Lung cancer; LIHC cis rs1401999 0.899 rs2313211 chr3:183738626 T/A cg01324343 chr3:183735012 ABCC5 0.77 12.6 0.56 3.56e-30 Anterior chamber depth; LIHC cis rs694739 0.628 rs11606081 chr11:64137875 T/C cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.02e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7618915 0.547 rs11719685 chr3:52676065 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 8.78 0.43 7.87e-17 Bipolar disorder; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg03874509 chr1:107600012 PRMT6 -0.78 -12.53 -0.56 6.65e-30 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs13064411 0.627 rs28536176 chr3:113143625 T/C cg18753928 chr3:113234510 CCDC52 -0.42 -5.74 -0.3 2.05e-8 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs4901869 0.902 rs10149194 chr14:59308198 A/G cg02291164 chr14:59296302 NA -0.49 -6.24 -0.32 1.31e-9 Panic disorder; LIHC cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg18876405 chr7:65276391 NA -0.56 -9.52 -0.46 3.24e-19 Calcium levels; LIHC cis rs79149102 0.579 rs58294763 chr15:75299768 G/A cg15902774 chr15:75289873 SCAMP5 0.43 6.44 0.33 4.07e-10 Lung cancer; LIHC cis rs17685 0.664 rs9801113 chr7:75792031 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.33 -0.32 7.51e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1892700 0.821 rs16990760 chr21:34924243 T/C cg14850771 chr21:34775459 IFNGR2 -0.43 -5.74 -0.3 2.09e-8 Educational attainment; LIHC cis rs9768139 0.596 rs7812034 chr7:158115222 A/G cg25566285 chr7:158114605 PTPRN2 0.23 6.22 0.32 1.43e-9 Calcium levels; LIHC cis rs11122272 0.670 rs2474632 chr1:231484361 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -10.99 -0.51 2.91e-24 Hemoglobin concentration; LIHC cis rs35110281 0.807 rs2838328 chr21:45023234 G/C cg04455712 chr21:45112962 RRP1B 0.45 7.76 0.39 1.02e-13 Mean corpuscular volume; LIHC cis rs9905704 0.647 rs9901655 chr17:56987142 G/A cg05425664 chr17:57184151 TRIM37 -0.45 -6.14 -0.31 2.33e-9 Testicular germ cell tumor; LIHC cis rs3857067 0.772 rs10516947 chr4:95110897 A/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs17309827 0.965 rs13206693 chr6:3433347 T/C cg00476032 chr6:3446245 SLC22A23 -0.32 -5.81 -0.3 1.45e-8 Crohn's disease; LIHC cis rs1267303 0.642 rs6696219 chr1:47000408 T/C cg25110126 chr1:46999211 NA 0.41 6.04 0.31 4.07e-9 Monobrow; LIHC cis rs1568889 1.000 rs1568889 chr11:28009463 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.48 6.63 0.34 1.28e-10 Bipolar disorder; LIHC cis rs7945705 0.967 rs10840141 chr11:8902218 T/C cg12365402 chr11:9010492 NRIP3 0.29 7.58 0.38 3.27e-13 Hemoglobin concentration; LIHC cis rs10493773 1.000 rs7523292 chr1:86134992 A/G cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.38 -0.37 1.19e-12 Urate levels in overweight individuals; LIHC cis rs2075371 1.000 rs2244694 chr7:133987093 C/T cg11752832 chr7:134001865 SLC35B4 0.52 7.83 0.39 6.14e-14 Mean platelet volume; LIHC cis rs1878931 0.501 rs9635563 chr16:3416940 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.71 10.67 0.5 3.76e-23 Body mass index (adult); LIHC cis rs317689 0.513 rs317659 chr12:69686132 T/A cg20891283 chr12:69753455 YEATS4 0.65 10.79 0.5 1.51e-23 Response to diuretic therapy; LIHC cis rs9430161 0.644 rs34365965 chr1:11034442 G/A cg02454025 chr1:11042201 C1orf127 0.96 18.61 0.71 6.65e-54 Ewing sarcoma; LIHC cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.84 8.87 0.43 4.19e-17 Platelet count; LIHC cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs986417 1.000 rs1254254 chr14:60831146 G/A cg27398547 chr14:60952738 C14orf39 -0.79 -9.02 -0.44 1.36e-17 Gut microbiota (bacterial taxa); LIHC cis rs2204008 0.806 rs11520229 chr12:38246448 C/A cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.56e-8 Bladder cancer; LIHC cis rs7617773 0.780 rs13085251 chr3:48340045 C/T cg11946769 chr3:48343235 NME6 0.92 11.62 0.53 1.58e-26 Coronary artery disease; LIHC cis rs1559088 0.847 rs7255968 chr19:33601902 A/T cg17764715 chr19:33622953 WDR88 0.48 6.93 0.35 2.07e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2242116 1.000 rs1138518 chr3:46944274 T/C cg27129171 chr3:47204927 SETD2 0.49 7.63 0.38 2.36e-13 Birth weight; LIHC cis rs11123170 0.650 rs2289897 chr2:113977454 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.51 6.22 0.32 1.46e-9 Renal function-related traits (BUN); LIHC cis rs7408868 0.908 rs62113793 chr19:15277336 G/A cg02272795 chr19:15279244 NOTCH3 -0.31 -5.75 -0.3 2.02e-8 Pulse pressure; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg22903471 chr2:27725779 GCKR 0.51 8.97 0.44 1.95e-17 Total body bone mineral density; LIHC cis rs17376456 0.935 rs13156002 chr5:93508931 G/A cg25358565 chr5:93447407 FAM172A 1.1 10.01 0.48 7.28e-21 Diabetic retinopathy; LIHC cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs7020830 0.825 rs66684257 chr9:37199087 G/T cg14294708 chr9:37120828 ZCCHC7 1.07 23.76 0.79 2.28e-74 Schizophrenia; LIHC cis rs644799 1.000 rs474442 chr11:95583995 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.88 16.08 0.66 9.9e-44 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7940866 0.678 rs61909201 chr11:130839547 C/T cg12179176 chr11:130786555 SNX19 0.66 9.01 0.44 1.5e-17 Schizophrenia; LIHC cis rs17685 0.753 rs6465000 chr7:75787417 G/A cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7131987 0.903 rs7974221 chr12:29399448 A/G cg00204748 chr12:29376779 FAR2 0.45 8.66 0.42 1.83e-16 QT interval; LIHC cis rs2153535 0.580 rs4960422 chr6:8459309 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs9583531 0.600 rs9521909 chr13:111362170 A/G cg24331049 chr13:111365604 ING1 0.78 13.14 0.58 3.32e-32 Coronary artery disease; LIHC cis rs6882046 0.513 rs647983 chr5:88048071 T/C cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs2637266 0.600 rs2395430 chr10:78465471 G/A cg18941641 chr10:78392320 NA 0.28 6.06 0.31 3.58e-9 Pulmonary function; LIHC cis rs1552244 0.816 rs13059144 chr3:10010197 A/C cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs11673344 0.633 rs519606 chr19:37433229 C/T cg27390819 chr19:37464633 NA -0.49 -5.84 -0.3 1.23e-8 Obesity-related traits; LIHC cis rs5769765 0.954 rs5770709 chr22:50245196 G/T cg22709217 chr22:50311962 ALG12;CRELD2 0.67 8.81 0.43 6.31e-17 Schizophrenia; LIHC cis rs11122272 0.732 rs999010 chr1:231495316 A/G cg06096015 chr1:231504339 EGLN1 0.52 9.54 0.46 2.83e-19 Hemoglobin concentration; LIHC cis rs9457247 0.534 rs7750593 chr6:167387359 C/G cg23791538 chr6:167370224 RNASET2 0.76 14.62 0.62 6.3e-38 Crohn's disease; LIHC cis rs7107174 0.901 rs10899498 chr11:78124575 C/G cg02023728 chr11:77925099 USP35 0.36 6.58 0.34 1.81e-10 Testicular germ cell tumor; LIHC cis rs782590 0.721 rs782641 chr2:55929294 C/T cg03859395 chr2:55845619 SMEK2 0.86 14.22 0.61 2.18e-36 Metabolic syndrome; LIHC cis rs9910055 0.529 rs228765 chr17:42186422 C/T cg19774624 chr17:42201019 HDAC5 0.48 6.12 0.31 2.58e-9 Total body bone mineral density; LIHC cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg05368731 chr17:41323189 NBR1 0.73 12.38 0.56 2.46e-29 Menopause (age at onset); LIHC cis rs1152591 1.000 rs2738413 chr14:64679960 A/G cg21174375 chr14:64681225 SYNE2 0.4 6.38 0.33 5.7e-10 Atrial fibrillation; LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg06873352 chr17:61820015 STRADA -0.59 -9.24 -0.45 2.67e-18 Height; LIHC cis rs904251 0.523 rs2797799 chr6:37483620 T/G cg25019722 chr6:37503610 NA -0.32 -5.74 -0.3 2.08e-8 Cognitive performance; LIHC cis rs9918079 0.560 rs13147590 chr4:15621188 A/G cg21123203 chr4:15471301 CC2D2A 0.43 6.78 0.34 5.4e-11 Obesity-related traits; LIHC cis rs6089584 0.888 rs6142927 chr20:60605848 A/G cg13770153 chr20:60521292 NA -0.35 -6.69 -0.34 9.26e-11 Body mass index; LIHC cis rs7520050 0.966 rs785520 chr1:46568836 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.81 0.3 1.45e-8 Red blood cell count;Reticulocyte count; LIHC trans rs7246657 0.891 rs7253114 chr19:37988725 G/A cg10208301 chr11:6592745 DNHD1 0.45 6.48 0.33 3.22e-10 Coronary artery calcification; LIHC cis rs6546550 0.935 rs11673826 chr2:70041033 G/A cg02498382 chr2:70120550 SNRNP27 -0.37 -6.29 -0.32 9.83e-10 Prevalent atrial fibrillation; LIHC cis rs10744422 1.000 rs1587856 chr12:123342229 A/G cg07706471 chr12:123319906 HIP1R -0.62 -8.2 -0.41 4.94e-15 Schizophrenia; LIHC trans rs11098499 0.731 rs6846966 chr4:120293208 A/G cg25214090 chr10:38739885 LOC399744 0.49 7.86 0.39 5.19e-14 Corneal astigmatism; LIHC cis rs4523957 0.928 rs216189 chr17:2187401 A/G cg16513277 chr17:2031491 SMG6 -0.46 -6.96 -0.35 1.7e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12477438 0.798 rs6759354 chr2:99632195 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.41 -0.53 8.75e-26 Chronic sinus infection; LIHC cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg03735888 chr19:58951602 ZNF132 0.39 6.92 0.35 2.31e-11 Uric acid clearance; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12960782 chr5:59996455 DEPDC1B 0.46 7.17 0.36 4.73e-12 Cognitive function; LIHC cis rs7568458 0.684 rs6731700 chr2:85760991 C/G cg02493740 chr2:85810744 VAMP5 -0.47 -7.8 -0.39 7.41e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs17685 0.753 rs4573217 chr7:75733946 G/A cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.76e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs7618501 0.521 rs34654589 chr3:49911449 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.64 0.34 1.25e-10 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06350524 chr2:169747178 SPC25 -0.48 -6.5 -0.33 2.88e-10 Pancreatic cancer; LIHC cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg12463550 chr7:65579703 CRCP 0.69 7.42 0.37 9.12e-13 Diabetic kidney disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05468429 chr6:7248862 RREB1 0.45 6.65 0.34 1.17e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs703842 0.616 rs10877023 chr12:58224199 C/A cg04478727 chr12:58166393 METTL1;FAM119B 0.67 9.5 0.46 3.84e-19 Multiple sclerosis; LIHC cis rs2180341 0.960 rs1543432 chr6:127698018 T/C cg24812749 chr6:127587940 RNF146 1.06 16.14 0.66 5.7e-44 Breast cancer; LIHC cis rs709400 0.628 rs72708854 chr14:103864885 T/C cg26031613 chr14:104095156 KLC1 0.79 10.1 0.48 3.61e-21 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05513509 chr18:20513742 RBBP8 -0.43 -6.05 -0.31 3.76e-9 Pancreatic cancer; LIHC cis rs1904096 0.506 rs10024642 chr4:95179295 A/G cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.32 -0.45 1.49e-18 Type 2 diabetes; LIHC cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.42 5.87 0.3 1.04e-8 Schizophrenia; LIHC cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg03806693 chr22:41940476 POLR3H -1.14 -13.34 -0.59 5.65e-33 Vitiligo; LIHC cis rs8062405 0.754 rs28410083 chr16:28631360 A/T cg07382826 chr16:28625726 SULT1A1 -0.45 -6.49 -0.33 3e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1448094 0.511 rs59668915 chr12:86197170 C/T cg02569458 chr12:86230093 RASSF9 0.46 5.99 0.31 5.3300000000000004e-09 Major depressive disorder; LIHC trans rs2243480 0.901 rs73148097 chr7:65431787 A/C cg10756647 chr7:56101905 PSPH 1.11 13.47 0.59 1.75e-33 Diabetic kidney disease; LIHC cis rs16854884 0.739 rs56196484 chr3:143786160 G/T cg06585982 chr3:143692056 C3orf58 0.54 6.73 0.34 7.19e-11 Economic and political preferences (feminism/equality); LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.59 8.58 0.42 3.46e-16 Lymphocyte counts; LIHC cis rs910316 0.763 rs175014 chr14:75456927 A/G cg11812906 chr14:75593930 NEK9 -0.75 -14.05 -0.6 1.01e-35 Height; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs227584 0.663 rs3180912 chr17:42259463 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.6 8.76 0.43 9.1e-17 Bone mineral density (hip);Bone mineral density; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00166836 chr6:149721425 MAP3K7IP2;SUMO4 0.44 6.05 0.31 3.8e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6762 0.719 rs7936806 chr11:839186 G/C cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.51 -0.46 3.63e-19 Mean platelet volume; LIHC cis rs3820068 0.581 rs58567918 chr1:15925823 A/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg20295408 chr7:1910781 MAD1L1 -0.41 -6.02 -0.31 4.55e-9 Bipolar disorder and schizophrenia; LIHC trans rs8073060 0.559 rs10438814 chr17:34007065 A/G cg19694781 chr19:47549865 TMEM160 -1.25 -13.18 -0.58 2.36e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs17106184 0.786 rs12091670 chr1:51200136 A/G cg07174182 chr1:51127561 FAF1 -0.62 -6.94 -0.35 1.98e-11 Type 2 diabetes; LIHC cis rs7617773 0.817 rs9837228 chr3:48324466 A/T cg11946769 chr3:48343235 NME6 -0.86 -11.17 -0.52 6.42e-25 Coronary artery disease; LIHC cis rs7100689 0.784 rs7082102 chr10:82104890 A/C cg00277334 chr10:82204260 NA -0.54 -6.72 -0.34 7.7e-11 Post bronchodilator FEV1; LIHC cis rs11252926 0.801 rs11252332 chr10:467318 A/T cg16346588 chr10:242978 ZMYND11 0.47 5.85 0.3 1.15e-8 Psychosis in Alzheimer's disease; LIHC cis rs6918586 0.616 rs198836 chr6:26113616 T/A cg18357526 chr6:26021779 HIST1H4A -0.55 -8.19 -0.41 5.15e-15 Schizophrenia; LIHC cis rs926392 0.965 rs6129166 chr20:37688825 T/C cg16355469 chr20:37678765 NA 0.37 5.89 0.3 9.19e-9 Dialysis-related mortality; LIHC cis rs11031096 0.621 rs11031159 chr11:4179695 T/G cg18678763 chr11:4115507 RRM1 -0.42 -5.97 -0.31 5.79e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs921968 0.510 rs2577761 chr2:219462500 G/A cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.63e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs10870270 1.000 rs7898755 chr10:133777122 G/A cg08754478 chr10:133766260 PPP2R2D -0.55 -8.1 -0.4 9.8e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs769267 0.930 rs3794993 chr19:19611550 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.49 7.33 0.37 1.63e-12 Tonsillectomy; LIHC cis rs7412746 0.658 rs11582281 chr1:150826831 T/C cg18016565 chr1:150552671 MCL1 0.56 10.29 0.49 8.1e-22 Melanoma; LIHC cis rs2952156 0.883 rs907089 chr17:37833600 C/T cg00129232 chr17:37814104 STARD3 -0.52 -9.95 -0.47 1.22e-20 Asthma; LIHC cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.86 0.3 1.12e-8 Calcium levels; LIHC cis rs7613875 0.580 rs11709503 chr3:49991167 G/T cg21467203 chr3:49911342 NA -0.54 -9.69 -0.46 8.77e-20 Body mass index; LIHC cis rs72653721 0.938 rs12529809 chr6:10980639 C/T cg13562911 chr6:11044106 ELOVL2 0.5 6.92 0.35 2.19e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 8.89e-15 Prudent dietary pattern; LIHC cis rs4555082 0.718 rs28513571 chr14:105709592 C/A cg06808227 chr14:105710500 BRF1 -0.59 -8.02 -0.4 1.71e-14 Mean platelet volume;Platelet distribution width; LIHC cis rs2991971 1.000 rs667626 chr1:46020551 T/C cg15605315 chr1:45957053 TESK2 0.45 5.9 0.3 8.93e-9 High light scatter reticulocyte count; LIHC cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.61e-12 Bipolar disorder; LIHC cis rs9503598 0.636 rs6596976 chr6:3466022 C/T cg00476032 chr6:3446245 SLC22A23 0.4 7.74 0.39 1.15e-13 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs8062405 0.964 rs7193733 chr16:28875482 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs919433 0.679 rs10931788 chr2:198531084 A/G cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10089 1.000 rs11957052 chr5:127524055 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.39 0.33 5.52e-10 Ileal carcinoids; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg11494091 chr17:61959527 GH2 0.44 8.08 0.4 1.11e-14 Prudent dietary pattern; LIHC cis rs7208859 0.623 rs9895785 chr17:29107708 C/T cg13385521 chr17:29058706 SUZ12P -0.79 -7.74 -0.39 1.13e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.53 0.49 1.23e-22 Vitiligo; LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.6 8.63 0.42 2.38e-16 Lymphocyte counts; LIHC cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg18230493 chr5:56204884 C5orf35 0.44 6.1 0.31 2.9e-9 Initial pursuit acceleration; LIHC cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg04944784 chr2:26401820 FAM59B -0.75 -9.27 -0.45 2.14e-18 Gut microbiome composition (summer); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08252533 chr2:238875575 UBE2F -0.41 -6.29 -0.32 9.84e-10 Pancreatic cancer; LIHC cis rs950169 0.919 rs17300292 chr15:84762568 G/C cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs2625529 0.775 rs35673773 chr15:72399886 C/A cg16672083 chr15:72433130 SENP8 -0.31 -5.86 -0.3 1.06e-8 Red blood cell count; LIHC trans rs3960554 1.000 rs2079477 chr7:75836549 C/G cg19862616 chr7:65841803 NCRNA00174 0.62 9.44 0.45 6.16e-19 Eotaxin levels; LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg07677032 chr17:61819896 STRADA 0.42 6.14 0.31 2.34e-9 Prudent dietary pattern; LIHC cis rs7523273 0.565 rs2796251 chr1:207903688 C/G cg22525895 chr1:207977042 MIR29B2 -0.55 -8.32 -0.41 2.11e-15 Schizophrenia; LIHC cis rs8060686 0.641 rs2418737 chr16:68122726 T/C cg09835421 chr16:68378352 PRMT7 -0.49 -6.0 -0.31 5.16e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs965469 0.779 rs6139071 chr20:3299054 A/G cg25506879 chr20:3388711 C20orf194 -0.53 -6.6 -0.34 1.53e-10 IFN-related cytopenia; LIHC cis rs947211 0.846 rs823155 chr1:205762946 T/C cg14893161 chr1:205819251 PM20D1 0.34 5.85 0.3 1.12e-8 Parkinson's disease; LIHC cis rs2839186 0.934 rs17182538 chr21:47705673 C/A cg00612595 chr21:47717864 NA -0.36 -5.91 -0.3 8.14e-9 Testicular germ cell tumor; LIHC cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg23205692 chr1:25664452 TMEM50A 0.37 5.86 0.3 1.06e-8 Erythrocyte sedimentation rate; LIHC cis rs61542988 0.535 rs10807813 chr7:22829961 C/T cg11367502 chr7:22862612 TOMM7 0.56 9.08 0.44 9.14e-18 Fibrinogen levels; LIHC cis rs2153535 0.580 rs6597332 chr6:8504748 C/G cg07606381 chr6:8435919 SLC35B3 0.79 11.76 0.54 4.68e-27 Motion sickness; LIHC cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.66e-9 Bipolar disorder; LIHC cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg11645453 chr3:52864694 ITIH4 -0.22 -6.08 -0.31 3.17e-9 Bipolar disorder; LIHC cis rs72627123 0.867 rs113768127 chr14:74467839 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.63 0.42 2.42e-16 Morning vs. evening chronotype; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs1395 0.710 rs2083363 chr2:27475318 G/C cg23587288 chr2:27483067 SLC30A3 -0.35 -6.64 -0.34 1.21e-10 Blood metabolite levels; LIHC cis rs798554 0.679 rs1639066 chr7:2892972 A/G cg19346786 chr7:2764209 NA -0.35 -5.73 -0.3 2.16e-8 Height; LIHC cis rs919433 0.510 rs34631382 chr2:198390009 C/T cg10820045 chr2:198174542 NA 0.5 7.84 0.39 5.61e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3096299 0.933 rs2965824 chr16:89455306 A/G cg01788221 chr16:89496183 ANKRD11 -0.37 -5.8 -0.3 1.5e-8 Multiple myeloma (IgH translocation); LIHC cis rs1865760 0.516 rs10807007 chr6:26048931 A/C cg18357526 chr6:26021779 HIST1H4A 0.51 7.46 0.37 7.01e-13 Height; LIHC cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg20891558 chr2:74357851 NA 0.81 16.55 0.67 1.33e-45 Gestational age at birth (maternal effect); LIHC cis rs10744422 1.000 rs1532835 chr12:123330665 G/A cg18912006 chr12:123335444 HIP1R -0.63 -7.58 -0.38 3.35e-13 Schizophrenia; LIHC cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg11645453 chr3:52864694 ITIH4 0.22 5.96 0.31 6.38e-9 Bipolar disorder; LIHC cis rs2304069 0.779 rs245081 chr5:149356075 G/T cg12661370 chr5:149340060 SLC26A2 0.55 7.82 0.39 6.61e-14 HIV-1 control; LIHC cis rs4908768 0.501 rs11121212 chr1:8725993 C/T cg20416874 chr1:8611966 RERE -0.64 -12.76 -0.57 8.8e-31 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs116095464 0.558 rs10057626 chr5:239720 T/G cg22857025 chr5:266934 NA -1.46 -17.68 -0.69 3.78e-50 Breast cancer; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg26338869 chr17:61819248 STRADA 0.6 8.78 0.43 8.04e-17 Prudent dietary pattern; LIHC cis rs12188164 0.525 rs1114665 chr5:452247 C/T cg08916839 chr5:415575 AHRR 0.29 6.21 0.32 1.58e-9 Cystic fibrosis severity; LIHC cis rs875971 0.830 rs778711 chr7:65851657 G/A cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC cis rs7086627 0.515 rs6585994 chr10:82191643 A/G cg01528321 chr10:82214614 TSPAN14 0.41 6.32 0.32 8.02e-10 Post bronchodilator FEV1; LIHC trans rs561341 1.000 rs72823787 chr17:30283809 A/T cg20587970 chr11:113659929 NA -1.46 -12.03 -0.55 4.97e-28 Hip circumference adjusted for BMI; LIHC cis rs1707322 1.000 rs10890380 chr1:46449469 A/G cg06784218 chr1:46089804 CCDC17 0.38 6.86 0.35 3.18e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6951245 0.608 rs10252234 chr7:1114381 C/T cg22907277 chr7:1156413 C7orf50 0.61 5.85 0.3 1.16e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9393692 0.905 rs7746807 chr6:26293338 C/A cg13736514 chr6:26305472 NA -0.38 -6.38 -0.33 5.91e-10 Educational attainment; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg26338869 chr17:61819248 STRADA 0.6 8.85 0.43 4.74e-17 Prudent dietary pattern; LIHC cis rs11577318 0.579 rs10794532 chr1:26694260 T/C cg18121669 chr1:26560928 CCDC21 -0.49 -7.24 -0.36 3.02e-12 Granulocyte percentage of myeloid white cells; LIHC trans rs9388451 0.626 rs9385383 chr6:126086290 G/T cg05039488 chr6:79577232 IRAK1BP1 -0.66 -11.13 -0.52 8.81e-25 Brugada syndrome; LIHC trans rs4714291 0.802 rs1474870 chr6:39980359 C/T cg02267698 chr19:7991119 CTXN1 0.39 6.51 0.33 2.61e-10 Strep throat; LIHC cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg21724239 chr8:58056113 NA 0.59 7.56 0.38 3.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs12188164 0.543 rs2672722 chr5:453567 G/A cg07599136 chr5:415885 AHRR 0.39 6.71 0.34 8.01e-11 Cystic fibrosis severity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14996935 chr7:91875850 KRIT1;ANKIB1 0.41 6.18 0.32 1.85e-9 Cognitive function; LIHC cis rs600806 0.850 rs4970729 chr1:109979202 G/A cg23091122 chr1:110024289 SYPL2 -0.51 -6.89 -0.35 2.77e-11 Intelligence (multi-trait analysis); LIHC cis rs1707322 1.000 rs1768807 chr1:46510570 A/G cg03146154 chr1:46216737 IPP -0.45 -7.39 -0.37 1.17e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9341808 0.556 rs10455370 chr6:81040867 A/G cg08355045 chr6:80787529 NA -0.31 -6.2 -0.32 1.67e-9 Sitting height ratio; LIHC cis rs2404602 0.583 rs3759853 chr15:76587777 C/T cg23625390 chr15:77176239 SCAPER 0.35 6.04 0.31 4.01e-9 Blood metabolite levels; LIHC cis rs950169 0.544 rs12913702 chr15:85153184 G/A cg03959625 chr15:84868606 LOC388152 0.42 5.76 0.3 1.87e-8 Schizophrenia; LIHC cis rs1008375 0.931 rs4479701 chr4:17571496 G/A cg02297831 chr4:17616191 MED28 0.47 6.89 0.35 2.62e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11098499 0.913 rs56122576 chr4:120129336 A/G cg09307838 chr4:120376055 NA 0.51 7.57 0.38 3.53e-13 Corneal astigmatism; LIHC cis rs7552404 0.727 rs7521344 chr1:76318325 C/T cg03433033 chr1:76189801 ACADM -0.55 -6.92 -0.35 2.3e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg13409248 chr3:40428643 ENTPD3 0.42 6.77 0.34 5.75e-11 Renal cell carcinoma; LIHC cis rs240764 0.680 rs12209777 chr6:101156639 G/A cg09795085 chr6:101329169 ASCC3 -0.4 -5.78 -0.3 1.7e-8 Neuroticism; LIHC cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.08 0.44 9.16e-18 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04197313 chr15:67547198 IQCH;AAGAB -0.44 -6.62 -0.34 1.42e-10 Cognitive function; LIHC cis rs2274273 0.686 rs28631821 chr14:55845987 T/C cg01864836 chr14:55583639 NA -0.41 -7.64 -0.38 2.15e-13 Protein biomarker; LIHC cis rs2806561 0.704 rs588387 chr1:23523689 A/G cg12483005 chr1:23474871 LUZP1 0.46 7.04 0.36 1.04e-11 Height; LIHC trans rs1814175 0.645 rs847630 chr11:49926360 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg02244288 chr16:89573955 SPG7 -0.31 -6.0 -0.31 4.99e-9 Multiple myeloma (IgH translocation); LIHC cis rs919433 0.927 rs1429418 chr2:198158151 G/C cg10820045 chr2:198174542 NA -0.58 -9.72 -0.47 6.93e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs1005277 0.579 rs1780122 chr10:38529509 C/A cg27523141 chr10:43048294 ZNF37B 0.39 6.6 0.34 1.59e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7584330 0.955 rs7581882 chr2:238390745 T/C cg14458575 chr2:238380390 NA 0.37 6.02 0.31 4.39e-9 Prostate cancer; LIHC cis rs1256061 0.624 rs1152586 chr14:64690784 T/C cg23250157 chr14:64679961 SYNE2 0.42 6.17 0.32 1.9e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs637571 0.528 rs566266 chr11:65573587 A/C cg04055107 chr11:65626734 MUS81;CFL1 -0.46 -6.61 -0.34 1.5e-10 Eosinophil percentage of white cells; LIHC cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.1 11.24 0.52 3.67e-25 Platelet count; LIHC trans rs783540 0.967 rs1145172 chr15:83223616 T/C cg18393722 chr15:85113863 UBE2QP1 -0.43 -7.51 -0.38 5.36e-13 Schizophrenia; LIHC cis rs73206853 0.563 rs1973505 chr12:111160003 A/G cg12870014 chr12:110450643 ANKRD13A -0.71 -8.43 -0.41 9.67e-16 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg02187348 chr16:89574699 SPG7 0.65 10.19 0.48 1.74e-21 Multiple myeloma (IgH translocation); LIHC cis rs2153535 0.580 rs6900007 chr6:8474035 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs477895 0.639 rs35858916 chr11:63950529 T/G cg18225595 chr11:63971243 STIP1 0.69 8.46 0.42 7.65e-16 Mean platelet volume; LIHC cis rs9814567 1.000 rs9990351 chr3:134239191 A/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.39 5.84 0.3 1.23e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7520050 0.897 rs4440807 chr1:46470878 T/C cg03146154 chr1:46216737 IPP -0.38 -6.21 -0.32 1.5e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2050392 0.517 rs589980 chr10:30756385 T/A cg25182066 chr10:30743637 MAP3K8 -0.64 -10.37 -0.49 4.38e-22 Inflammatory bowel disease; LIHC cis rs16854884 0.632 rs35629416 chr3:143748424 C/T cg06585982 chr3:143692056 C3orf58 0.49 6.16 0.32 2e-9 Economic and political preferences (feminism/equality); LIHC cis rs12472274 0.646 rs10929269 chr2:239097423 A/G cg17459225 chr2:239074497 NA 0.72 11.23 0.52 4.1e-25 Phospholipid levels (plasma); LIHC cis rs11229555 0.574 rs12292024 chr11:58186716 C/T cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13393964 chr16:20753279 THUMPD1 0.44 6.05 0.31 3.9e-9 Pancreatic cancer; LIHC cis rs16828019 0.852 rs34286980 chr1:41608389 A/G cg20697417 chr1:41786797 NA 0.35 6.64 0.34 1.24e-10 Intelligence (multi-trait analysis); LIHC cis rs7762018 1.000 rs6941766 chr6:170131653 A/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.56 6.83 0.35 3.81e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11711311 1.000 rs12637066 chr3:113527574 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.84 -0.35 3.76e-11 IgG glycosylation; LIHC cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg11062466 chr8:58055876 NA 0.48 7.01 0.35 1.25e-11 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09825030 chr2:85568866 NA 0.45 6.09 0.31 3.06e-9 Hepatitis; LIHC cis rs8180040 0.593 rs12715421 chr3:47084859 A/G cg27129171 chr3:47204927 SETD2 0.55 9.14 0.44 5.79e-18 Colorectal cancer; LIHC cis rs875971 0.862 rs7803416 chr7:65954199 A/G cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs2439831 0.867 rs6493082 chr15:43634808 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC cis rs1801251 1.000 rs6437074 chr2:233712296 C/T cg08000102 chr2:233561755 GIGYF2 -0.76 -11.5 -0.53 4.41e-26 Coronary artery disease; LIHC cis rs7208859 0.623 rs58089675 chr17:29196764 C/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs244293 0.931 rs2787484 chr17:53210120 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.45 -0.37 7.67e-13 Menarche (age at onset); LIHC cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg03264133 chr6:25882463 NA -0.46 -5.93 -0.31 7.62e-9 Intelligence (multi-trait analysis); LIHC cis rs12711979 0.509 rs13000873 chr2:3823705 T/C cg17052675 chr2:3827356 NA -0.7 -15.3 -0.64 1.32e-40 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg17971929 chr21:40555470 PSMG1 0.74 8.96 0.44 2.1e-17 Cognitive function; LIHC cis rs12579753 0.709 rs34503239 chr12:82124199 G/T cg07988820 chr12:82153109 PPFIA2 -0.5 -5.92 -0.3 7.99e-9 Resting heart rate; LIHC cis rs2576037 0.583 rs501062 chr18:44411135 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.93 -0.31 7.49e-9 Personality dimensions; LIHC cis rs367615 0.918 rs10055528 chr5:108861129 G/T cg17395555 chr5:108820864 NA 0.35 7.15 0.36 5.23e-12 Colorectal cancer (SNP x SNP interaction); LIHC trans rs637571 0.528 rs11602769 chr11:65594139 T/C cg17712092 chr4:129076599 LARP1B -0.69 -10.61 -0.5 6.52e-23 Eosinophil percentage of white cells; LIHC cis rs736408 0.608 rs2239547 chr3:52855229 T/C cg18404041 chr3:52824283 ITIH1 -0.42 -6.09 -0.31 3.08e-9 Bipolar disorder; LIHC cis rs716804 0.740 rs10840385 chr11:10307636 T/A cg01453529 chr11:10209919 SBF2 -0.29 -5.78 -0.3 1.64e-8 Neuroticism; LIHC cis rs9814567 1.000 rs9289475 chr3:134236459 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6977660 0.943 rs6959678 chr7:19821759 C/A cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs62079673 0.527 rs9788998 chr17:80605644 A/G cg10281770 chr17:80606947 WDR45L 0.71 12.24 0.55 8.34e-29 Breast cancer; LIHC cis rs4713118 0.512 rs2622319 chr6:28120401 G/C cg16479474 chr6:28041457 NA 0.38 6.44 0.33 4.05e-10 Parkinson's disease; LIHC cis rs9916302 0.861 rs10491129 chr17:37461643 T/G cg07936489 chr17:37558343 FBXL20 0.84 13.68 0.59 2.79e-34 Glomerular filtration rate (creatinine); LIHC cis rs9457247 0.508 rs9457268 chr6:167503639 A/T cg23791538 chr6:167370224 RNASET2 -0.44 -7.23 -0.36 3.21e-12 Crohn's disease; LIHC cis rs12477438 0.765 rs12612688 chr2:99613091 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.25 -0.41 3.37e-15 Chronic sinus infection; LIHC cis rs12926788 0.546 rs200537 chr16:24747787 G/C cg00152838 chr16:24741724 TNRC6A 0.49 6.15 0.32 2.19e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs3780378 0.875 rs10115312 chr9:5003973 G/T cg02405213 chr9:5042618 JAK2 -0.47 -7.91 -0.39 3.6e-14 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs11577318 0.853 rs7541333 chr1:26622889 C/T cg00852783 chr1:26633632 UBXN11 0.39 6.63 0.34 1.34e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg05527609 chr1:210001259 C1orf107 0.43 6.34 0.32 7.27e-10 Cleft lip with or without cleft palate; LIHC cis rs2274273 0.870 rs8018110 chr14:55641714 C/T cg04306507 chr14:55594613 LGALS3 0.32 6.12 0.31 2.51e-9 Protein biomarker; LIHC cis rs1862618 0.671 rs2591961 chr5:56238597 A/G cg12311346 chr5:56204834 C5orf35 0.43 5.88 0.3 9.81e-9 Initial pursuit acceleration; LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg22963979 chr7:1858916 MAD1L1 -0.45 -7.27 -0.37 2.51e-12 Bipolar disorder and schizophrenia; LIHC cis rs9326248 0.953 rs488962 chr11:117072525 C/T cg11861562 chr11:117069780 TAGLN -0.48 -7.88 -0.39 4.56e-14 Blood protein levels; LIHC trans rs208520 0.690 rs10455595 chr6:66738034 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.93 0.43 2.63e-17 Exhaled nitric oxide output; LIHC cis rs11711311 1.000 rs4362695 chr3:113534856 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.25 -0.36 2.81e-12 IgG glycosylation; LIHC cis rs9814567 1.000 rs7648990 chr3:134244390 T/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13104704 chr22:24192004 NA 0.48 7.16 0.36 4.93e-12 Cognitive function; LIHC cis rs2075371 1.000 rs2544213 chr7:133982867 G/C cg20476274 chr7:133979776 SLC35B4 0.75 12.55 0.56 5.49e-30 Mean platelet volume; LIHC cis rs10751667 1.000 rs10794357 chr11:973374 T/C cg06064525 chr11:970664 AP2A2 -0.49 -12.32 -0.55 3.93e-29 Alzheimer's disease (late onset); LIHC cis rs16828019 0.852 rs12048187 chr1:41616183 A/G cg03962019 chr1:41807865 NA 0.53 7.51 0.38 5.27e-13 Intelligence (multi-trait analysis); LIHC cis rs6840360 1.000 rs10007015 chr4:152603528 C/G cg22705602 chr4:152727874 NA -0.31 -6.44 -0.33 4.04e-10 Intelligence (multi-trait analysis); LIHC cis rs9549367 0.774 rs9549364 chr13:113903745 T/C cg00898013 chr13:113819073 PROZ -0.42 -7.18 -0.36 4.24e-12 Platelet distribution width; LIHC cis rs7903847 0.642 rs10882911 chr10:99138064 A/C cg08345082 chr10:99160200 RRP12 -0.38 -6.25 -0.32 1.23e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg00149659 chr3:10157352 C3orf10 0.69 7.06 0.36 9.61e-12 Alzheimer's disease; LIHC cis rs12477438 0.501 rs11688004 chr2:99735052 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 9.9 0.47 1.76e-20 Chronic sinus infection; LIHC trans rs950169 0.545 rs4842841 chr15:84641125 G/A cg00571809 chr1:3397113 ARHGEF16 0.38 6.17 0.32 1.91e-9 Schizophrenia; LIHC cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg15921436 chr17:44337874 NA 0.62 6.46 0.33 3.53e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6089829 0.925 rs6122086 chr20:61664528 T/C cg03213289 chr20:61660250 NA 0.5 8.89 0.43 3.7e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs7089973 0.604 rs35319791 chr10:116602296 C/A cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs477692 0.870 rs512655 chr10:131424547 T/A cg19680672 chr10:131412579 MGMT -0.42 -6.58 -0.34 1.75e-10 Response to temozolomide; LIHC cis rs7592578 0.766 rs62182885 chr2:191437024 A/G cg10560079 chr2:191398806 TMEM194B -0.9 -12.49 -0.56 9.66e-30 Diastolic blood pressure; LIHC cis rs2073300 0.609 rs74809795 chr20:23372383 A/C cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs916888 0.687 rs199456 chr17:44797919 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.97 0.35 1.65e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1863824 0.625 rs2018507 chr10:88163251 A/G cg07322936 chr10:88137208 NA 0.45 5.87 0.3 1.03e-8 Schizophrenia; LIHC cis rs344364 0.511 rs2982452 chr16:1949511 G/A cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs7095607 0.704 rs6480309 chr10:69953066 G/A cg18986048 chr10:69913749 MYPN 0.43 6.53 0.33 2.36e-10 Lung function (FVC); LIHC cis rs9309711 0.922 rs11679058 chr2:3483813 C/G cg10845886 chr2:3471009 TTC15 -0.62 -11.78 -0.54 4.19e-27 Neurofibrillary tangles; LIHC cis rs12478296 0.901 rs7603560 chr2:243043256 C/T cg06360820 chr2:242988706 NA -0.95 -12.38 -0.56 2.37e-29 Obesity-related traits; LIHC cis rs2257205 0.667 rs9916423 chr17:56773834 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -6.56 -0.33 2e-10 Pancreatic cancer; LIHC cis rs4808199 0.948 rs2301671 chr19:19466269 C/T cg03709012 chr19:19516395 GATAD2A 0.99 15.8 0.65 1.29e-42 Nonalcoholic fatty liver disease; LIHC cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.89e-30 Menopause (age at onset); LIHC cis rs9325144 0.555 rs7960411 chr12:38703019 A/G cg26384229 chr12:38710491 ALG10B -0.57 -7.86 -0.39 4.89e-14 Morning vs. evening chronotype; LIHC cis rs10078 0.559 rs2037077 chr5:447226 A/G cg24955955 chr5:415729 AHRR 0.6 10.97 0.51 3.36e-24 Fat distribution (HIV); LIHC cis rs2933343 1.000 rs1683776 chr3:128622760 G/T cg25356066 chr3:128598488 ACAD9 0.52 6.77 0.34 5.59e-11 IgG glycosylation; LIHC cis rs2016586 0.802 rs2009168 chr22:36117854 A/G cg26342177 chr22:36113512 APOL5 0.4 6.81 0.35 4.37e-11 Body mass index; LIHC cis rs9326248 1.000 rs4938344 chr11:117003749 G/A cg26566898 chr11:117069891 TAGLN 0.47 7.36 0.37 1.39e-12 Blood protein levels; LIHC cis rs7520050 0.966 rs11211234 chr1:46438787 C/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 6.03 0.31 4.24e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2836974 0.526 rs1888488 chr21:40686521 C/T cg11890956 chr21:40555474 PSMG1 -0.46 -7.51 -0.38 5.36e-13 Cognitive function; LIHC trans rs1005277 0.579 rs1780122 chr10:38529509 C/A cg17830980 chr10:43048298 ZNF37B -0.52 -9.97 -0.47 1.01e-20 Extrinsic epigenetic age acceleration; LIHC cis rs12824058 0.831 rs11060825 chr12:130807905 A/G cg24229701 chr12:130821962 PIWIL1 0.45 6.82 0.35 4.24e-11 Menopause (age at onset); LIHC cis rs910316 1.000 rs175442 chr14:75603564 T/C cg11812906 chr14:75593930 NEK9 -0.75 -14.74 -0.62 2.01e-38 Height; LIHC cis rs6121246 0.567 rs6120879 chr20:30202961 T/C cg13852791 chr20:30311386 BCL2L1 0.73 6.52 0.33 2.58e-10 Mean corpuscular hemoglobin; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg27555392 chr1:16679092 FBXO42 0.47 6.8 0.35 4.68e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs17345786 0.861 rs17402964 chr3:101067945 C/T cg12386194 chr3:101231763 SENP7 0.56 7.29 0.37 2.1e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs846111 1.000 rs846111 chr1:6279370 G/C cg15892785 chr1:6309343 GPR153 -0.49 -5.82 -0.3 1.39e-8 QT interval; LIHC cis rs7100689 0.577 rs2342813 chr10:82046302 T/G cg00277334 chr10:82204260 NA -0.51 -6.4 -0.33 5.12e-10 Post bronchodilator FEV1; LIHC cis rs2304069 0.909 rs10038824 chr5:149369776 G/A cg12661370 chr5:149340060 SLC26A2 -0.55 -6.65 -0.34 1.16e-10 HIV-1 control; LIHC cis rs67460515 0.563 rs4494975 chr3:160866768 C/T cg17135325 chr3:160939158 NMD3 0.58 8.15 0.4 6.81e-15 Parkinson's disease; LIHC cis rs6951245 1.000 rs75488469 chr7:1102122 A/G cg08132940 chr7:1081526 C7orf50 -0.8 -6.73 -0.34 7.22e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2637266 1.000 rs3923670 chr10:78375001 C/G cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC trans rs875971 0.660 rs7807930 chr7:66087165 C/T cg26939375 chr7:64535504 NA -0.44 -7.05 -0.36 1.01e-11 Aortic root size; LIHC cis rs11148252 1.000 rs4886018 chr13:52990717 C/T cg00495681 chr13:53174319 NA 0.41 6.73 0.34 6.99e-11 Lewy body disease; LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg08677398 chr8:58056175 NA 0.41 6.32 0.32 8.32e-10 Developmental language disorder (linguistic errors); LIHC trans rs2243480 1.000 rs7794661 chr7:65389730 T/C cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs3741151 0.892 rs7930454 chr11:73085034 T/C cg17517138 chr11:73019481 ARHGEF17 0.78 6.12 0.31 2.63e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs11785400 1.000 rs3735999 chr8:143746069 T/C cg24634471 chr8:143751801 JRK 0.51 8.14 0.4 7.61e-15 Schizophrenia; LIHC cis rs7954584 0.520 rs1169095 chr12:122465738 G/A cg21016266 chr12:122356598 WDR66 -0.38 -5.98 -0.31 5.52e-9 Mean corpuscular volume; LIHC cis rs34779708 0.966 rs4294520 chr10:35422506 C/T cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9303401 0.659 rs16943176 chr17:56769887 G/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs3008870 1.000 rs3008854 chr1:67385951 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.45 0.66 3.47e-45 Lymphocyte percentage of white cells; LIHC trans rs7227401 1.000 rs7227401 chr18:21938658 G/T cg27130769 chr7:5417105 TNRC18 0.69 6.18 0.32 1.83e-9 Osteoporosis-related phenotypes; LIHC trans rs75804782 0.641 rs60841092 chr2:239349640 G/A cg01134436 chr17:81009848 B3GNTL1 0.84 7.2 0.36 3.88e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs470119 1.000 rs131801 chr22:50966634 G/T cg12969734 chr22:50962224 SCO2 0.48 7.71 0.38 1.37e-13 Mean corpuscular hemoglobin; LIHC cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg02353165 chr6:42928485 GNMT 0.78 12.04 0.55 4.41e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4253772 0.513 rs6008700 chr22:46722560 C/T cg24881330 chr22:46731750 TRMU 0.64 6.86 0.35 3.25e-11 LDL cholesterol;Cholesterol, total; LIHC cis rs6933660 0.683 rs8180642 chr6:151756612 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.48 7.11 0.36 6.65e-12 Menarche (age at onset); LIHC cis rs847649 0.699 rs10241865 chr7:102527517 G/A cg18108683 chr7:102477205 FBXL13 -0.48 -7.41 -0.37 1.03e-12 Morning vs. evening chronotype; LIHC cis rs765787 0.530 rs55771002 chr15:45541566 T/C cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC cis rs6840360 0.550 rs4696269 chr4:152481704 T/A cg22705602 chr4:152727874 NA -0.33 -6.46 -0.33 3.71e-10 Intelligence (multi-trait analysis); LIHC cis rs10883723 0.810 rs7079810 chr10:104243883 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.37 0.56 2.56e-29 Allergic disease (asthma, hay fever or eczema); LIHC cis rs28647808 0.881 rs4549850 chr9:136265239 T/C cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs611744 0.967 rs645241 chr8:109190963 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs4665809 0.838 rs6546749 chr2:26306288 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.51 -0.46 3.55e-19 Gut microbiome composition (summer); LIHC cis rs7772486 0.875 rs2748501 chr6:146312258 G/A cg13319975 chr6:146136371 FBXO30 -0.39 -6.36 -0.33 6.6e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2455799 0.613 rs7617039 chr3:15800740 A/G cg12698662 chr3:15914712 MIR563 0.35 6.54 0.33 2.23e-10 Mean platelet volume; LIHC cis rs929354 0.742 rs7784442 chr7:156934475 G/C cg05182265 chr7:156933206 UBE3C -0.31 -5.74 -0.3 2.1e-8 Body mass index; LIHC cis rs9296092 0.517 rs9461877 chr6:33516667 C/T cg13560919 chr6:33536144 NA -0.39 -6.33 -0.32 7.6e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs55665837 0.701 rs10160597 chr11:14603992 G/A cg25251204 chr11:14927456 NA 0.43 6.0 0.31 4.94e-9 Vitamin D levels; LIHC cis rs11227306 0.812 rs11227310 chr11:65584733 A/T cg00576331 chr11:65640516 EFEMP2 -0.41 -5.86 -0.3 1.07e-8 DNA methylation (variation); LIHC cis rs74417235 0.684 rs12655636 chr5:154057618 T/C cg08893839 chr5:154027129 NA 0.49 6.69 0.34 8.95e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs600806 0.778 rs1525916 chr1:110010949 A/G cg10127483 chr1:110009974 SYPL2 0.45 5.75 0.3 1.95e-8 Intelligence (multi-trait analysis); LIHC cis rs9517320 0.515 rs4772101 chr13:99207554 G/A cg20487152 chr13:99095054 FARP1 -0.37 -6.18 -0.32 1.82e-9 Longevity; LIHC trans rs1432089 0.773 rs72700812 chr4:171785370 C/A cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs7937682 0.961 rs491937 chr11:111494947 A/T cg09085632 chr11:111637200 PPP2R1B -0.89 -10.94 -0.51 4.26e-24 Primary sclerosing cholangitis; LIHC cis rs412000 0.560 rs4793583 chr17:56451407 A/C cg05425664 chr17:57184151 TRIM37 0.51 7.26 0.37 2.58e-12 Primary tooth development (time to first tooth eruption); LIHC cis rs2637266 1.000 rs10219021 chr10:78364516 C/T cg18941641 chr10:78392320 NA 0.3 6.49 0.33 3.01e-10 Pulmonary function; LIHC cis rs6582630 0.599 rs8175936 chr12:38426315 C/G cg26384229 chr12:38710491 ALG10B -0.45 -5.88 -0.3 1e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs546131 0.642 rs1949046 chr11:34836989 T/C cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.28 -0.32 1.01e-9 Lung disease severity in cystic fibrosis; LIHC cis rs1707322 0.717 rs28752166 chr1:46213309 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg02951883 chr7:2050386 MAD1L1 -0.68 -10.98 -0.51 3.04e-24 Bipolar disorder and schizophrenia; LIHC cis rs7647973 0.696 rs3087866 chr3:49054692 A/G cg07636037 chr3:49044803 WDR6 0.76 9.07 0.44 9.49e-18 Menarche (age at onset); LIHC cis rs422249 0.512 rs174576 chr11:61603510 C/A cg27386326 chr11:61587980 NA 0.7 14.97 0.63 2.57e-39 Trans fatty acid levels; LIHC cis rs11958404 0.615 rs10061079 chr5:157449968 G/C cg05962755 chr5:157440814 NA 0.59 7.83 0.39 6.15e-14 IgG glycosylation; LIHC cis rs909002 0.800 rs7549590 chr1:32109849 G/A cg13919466 chr1:32135498 COL16A1 -0.37 -6.72 -0.34 7.52e-11 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg17554472 chr22:41940697 POLR3H 0.51 5.81 0.3 1.45e-8 Vitiligo; LIHC cis rs10865541 0.902 rs10173635 chr2:3421213 G/A cg11642891 chr2:3452563 TTC15 -0.45 -7.19 -0.36 4.2e-12 Obesity-related traits; LIHC cis rs7810240 0.967 rs2373695 chr7:150083090 C/T cg10018233 chr7:150070692 REPIN1 -0.41 -6.52 -0.33 2.45e-10 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; LIHC cis rs9768139 0.733 rs35016950 chr7:158118710 C/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.96 -0.31 6.31e-9 Calcium levels; LIHC cis rs332507 0.571 rs2291988 chr3:124369650 T/C cg05980111 chr3:124395277 KALRN 0.31 6.03 0.31 4.23e-9 Plateletcrit; LIHC trans rs7448080 0.702 rs76712096 chr5:123344307 A/G cg23779626 chr6:33864747 NA -0.59 -6.06 -0.31 3.62e-9 Alcohol dependence (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09920427 chr19:12777674 MORG1;MAN2B1 0.43 7.12 0.36 6.28e-12 Cognitive function; LIHC cis rs34779708 0.966 rs35777088 chr10:35409048 T/C cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7937890 0.874 rs6486191 chr11:14403739 G/A cg02251663 chr11:14281053 SPON1 -0.42 -5.81 -0.3 1.41e-8 Mitochondrial DNA levels; LIHC cis rs798554 0.757 rs960273 chr7:2857876 T/C cg19346786 chr7:2764209 NA -0.48 -7.11 -0.36 6.69e-12 Height; LIHC cis rs1949733 0.543 rs62287446 chr4:8535988 G/A cg11789530 chr4:8429930 ACOX3 -0.55 -7.8 -0.39 7.8e-14 Response to antineoplastic agents; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg25404025 chr5:52777789 FST -0.39 -6.3 -0.32 9.42e-10 Migraine with aura; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg25846302 chr15:102501640 WASH3P 0.5 6.65 0.34 1.17e-10 Hepatitis; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.74 -0.47 5.88e-20 Initial pursuit acceleration; LIHC cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg20295408 chr7:1910781 MAD1L1 -0.51 -7.18 -0.36 4.45e-12 Bipolar disorder and schizophrenia; LIHC cis rs10911232 0.507 rs4575047 chr1:182976028 A/G ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Hypertriglyceridemia; LIHC cis rs17095355 0.901 rs12240333 chr10:111743972 T/A cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.84 -0.3 1.24e-8 Biliary atresia; LIHC cis rs9596863 0.898 rs9563174 chr13:54335298 G/A ch.13.53330881F chr13:54432880 NA 0.45 6.18 0.32 1.78e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs507080 0.769 rs570836 chr11:118512162 G/A cg04173919 chr11:118528438 PHLDB1 0.32 5.83 0.3 1.29e-8 Serum metabolite levels; LIHC trans rs10411161 0.748 rs58120918 chr19:52368346 C/T cg22319618 chr22:45562946 NUP50 -0.53 -6.52 -0.33 2.49e-10 Breast cancer; LIHC cis rs9467773 0.933 rs2024970 chr6:26497520 T/A cg11502198 chr6:26597334 ABT1 0.41 5.76 0.3 1.86e-8 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg12463550 chr7:65579703 CRCP -0.72 -7.57 -0.38 3.61e-13 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01812826 chr8:123793836 ZHX2 0.42 6.03 0.31 4.14e-9 Lung function (FEV1/FVC); LIHC cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.58 0.46 1.99e-19 Bipolar disorder; LIHC cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg18404041 chr3:52824283 ITIH1 -0.5 -8.43 -0.41 9.5e-16 Bipolar disorder; LIHC cis rs1008375 1.000 rs2315556 chr4:17670861 T/C cg02297831 chr4:17616191 MED28 0.42 6.66 0.34 1.13e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7223966 1.000 rs9901507 chr17:61765524 G/A cg05941027 chr17:61774174 LIMD2 0.3 5.99 0.31 5.18e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3857067 1.000 rs7685048 chr4:95027784 C/T cg11021082 chr4:95130006 SMARCAD1 -0.41 -7.35 -0.37 1.43e-12 QT interval; LIHC cis rs1008375 0.898 rs10008445 chr4:17593978 G/T cg16339924 chr4:17578868 LAP3 0.46 6.43 0.33 4.32e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg18252515 chr7:66147081 NA -1.24 -16.01 -0.65 1.96e-43 Diabetic kidney disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16910340 chr3:28390302 AZI2 0.46 6.62 0.34 1.39e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg12271800 chr19:59028764 ZBTB45 0.39 6.16 0.32 2.07e-9 Immature fraction of reticulocytes; LIHC cis rs8180040 0.593 rs12715421 chr3:47084859 A/G cg16586182 chr3:47516702 SCAP -0.47 -8.52 -0.42 5.13e-16 Colorectal cancer; LIHC cis rs9303401 0.703 rs8077052 chr17:57208921 T/G cg02118635 chr17:56770003 RAD51C;TEX14 0.41 6.03 0.31 4.29e-9 Cognitive test performance; LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC cis rs2979489 0.891 rs16877096 chr8:30364388 T/C cg26383811 chr8:30366931 RBPMS -0.77 -12.63 -0.56 2.88e-30 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs12586317 0.547 rs10146699 chr14:35483577 G/A cg05294307 chr14:35346193 BAZ1A -0.49 -7.42 -0.37 9.63e-13 Psoriasis; LIHC cis rs7614311 0.681 rs73117042 chr3:63896543 T/C cg22134162 chr3:63841271 THOC7 -0.53 -6.02 -0.31 4.53e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs916888 0.773 rs199443 chr17:44819565 C/T cg01570182 chr17:44337453 NA 1.01 10.14 0.48 2.67e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9916302 0.904 rs4239222 chr17:37696235 A/C cg07936489 chr17:37558343 FBXL20 0.81 12.73 0.57 1.24e-30 Glomerular filtration rate (creatinine); LIHC trans rs2742417 0.603 rs2742448 chr3:45764246 C/T cg03814316 chr16:29997655 TAOK2 0.41 6.35 0.32 6.99e-10 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs2242116 0.896 rs724449 chr3:46935681 C/T cg02527881 chr3:46936655 PTH1R -0.54 -11.92 -0.54 1.2e-27 Birth weight; LIHC cis rs12701220 0.655 rs9638973 chr7:1133678 A/G cg26769984 chr7:1090371 C7orf50 0.46 5.82 0.3 1.34e-8 Bronchopulmonary dysplasia; LIHC cis rs3096299 0.869 rs748941 chr16:89440754 T/A cg06640241 chr16:89574553 SPG7 0.63 10.19 0.48 1.86e-21 Multiple myeloma (IgH translocation); LIHC cis rs12220238 1.000 rs11000890 chr10:75904073 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.36 0.33 6.48e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1034435 0.755 rs6007871 chr22:48894392 C/G cg05992904 chr22:48892994 FAM19A5 -0.52 -10.55 -0.5 1.01e-22 Late-onset Alzheimer's disease; LIHC cis rs227584 0.501 rs62078931 chr17:42198059 A/C cg19774624 chr17:42201019 HDAC5 0.66 9.92 0.47 1.47e-20 Bone mineral density (hip);Bone mineral density; LIHC cis rs2760061 0.598 rs849904 chr1:228137145 G/C cg02753203 chr1:228287806 NA -0.47 -7.51 -0.38 5.1e-13 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06649899 chr16:67261154 TMEM208;LRRC29 0.45 6.62 0.34 1.39e-10 Pancreatic cancer; LIHC cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg13699009 chr12:122356056 WDR66 -0.46 -7.71 -0.38 1.35e-13 Mean corpuscular volume; LIHC cis rs4908768 0.501 rs12061328 chr1:8531963 C/T cg20416874 chr1:8611966 RERE -0.68 -14.66 -0.62 4.19e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg17328964 chr8:145687451 CYHR1 0.46 7.53 0.38 4.68e-13 Age at first birth; LIHC cis rs6001982 0.541 rs7284768 chr22:41047764 C/T cg14879645 chr22:41048474 NA -0.4 -5.81 -0.3 1.46e-8 Breast cancer; LIHC cis rs8064299 0.584 rs2384957 chr17:72784630 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.73 12.87 0.57 3.54e-31 Monocyte count; LIHC cis rs3768617 0.565 rs4233194 chr1:183060917 G/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.27 0.49 9.73e-22 Fuchs's corneal dystrophy; LIHC cis rs240764 0.658 rs1336244 chr6:101197953 C/T cg09795085 chr6:101329169 ASCC3 -0.45 -6.68 -0.34 9.69e-11 Neuroticism; LIHC cis rs875971 1.000 rs778722 chr7:65844828 T/C cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg16377998 chr18:6284498 L3MBTL4 0.37 6.34 0.32 7.34e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03258011 chr17:54857409 NA 0.42 6.3 0.32 9.01e-10 Cognitive function; LIHC cis rs11758351 0.660 rs55848726 chr6:26224434 T/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs2842992 0.724 rs15982 chr6:160199687 T/C cg19482086 chr6:160211437 TCP1;MRPL18 0.66 12.32 0.55 3.94e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs875971 0.862 rs10261398 chr7:65750164 A/G cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs919433 0.756 rs7575389 chr2:198198489 A/G cg03934865 chr2:198174659 NA -0.54 -8.38 -0.41 1.42e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7927592 0.956 rs10896341 chr11:68313180 G/A cg01657329 chr11:68192670 LRP5 -0.47 -6.15 -0.32 2.22e-9 Total body bone mineral density; LIHC cis rs748404 0.588 rs2255410 chr15:43831097 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.39 5.9 0.3 8.61e-9 Lung cancer; LIHC cis rs2710642 0.721 rs6757128 chr2:62891752 C/T cg17519650 chr2:63277830 OTX1 -0.48 -7.16 -0.36 4.81e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs9583531 0.574 rs61971615 chr13:111353111 C/T cg15841412 chr13:111365552 ING1 -0.47 -5.9 -0.3 8.7e-9 Coronary artery disease; LIHC cis rs35110281 0.627 rs1595167 chr21:44965874 T/G cg01579765 chr21:45077557 HSF2BP -0.33 -6.15 -0.32 2.2e-9 Mean corpuscular volume; LIHC cis rs9916302 0.861 rs11078913 chr17:37671714 G/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.26 -0.58 1.16e-32 Glomerular filtration rate (creatinine); LIHC cis rs7945718 0.811 rs7104832 chr11:12786489 A/G cg25843174 chr11:12811716 TEAD1 0.34 7.76 0.39 9.99e-14 Educational attainment (years of education); LIHC cis rs3770081 1.000 rs2278087 chr2:86281946 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -8.69 -0.43 1.57e-16 Facial emotion recognition (sad faces); LIHC cis rs477692 0.569 rs871028 chr10:131293478 C/T cg05714579 chr10:131428358 MGMT -0.42 -6.85 -0.35 3.35e-11 Response to temozolomide; LIHC cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg18404041 chr3:52824283 ITIH1 -0.55 -8.97 -0.44 1.97e-17 Bipolar disorder; LIHC cis rs9300255 0.602 rs2510885 chr12:123614813 G/C cg00376283 chr12:123451042 ABCB9 0.6 8.03 0.4 1.57e-14 Neutrophil percentage of white cells; LIHC cis rs34779708 0.931 rs13376801 chr10:35370443 T/C cg04310649 chr10:35416472 CREM -0.42 -5.78 -0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9911578 0.967 rs4598970 chr17:57076893 T/A cg05425664 chr17:57184151 TRIM37 0.6 9.09 0.44 8.26e-18 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.658 rs4970986 chr1:150907955 A/G cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg06238570 chr21:40685208 BRWD1 0.61 7.28 0.37 2.36e-12 Cognitive function; LIHC trans rs9356009 0.764 rs9347727 chr6:158293573 T/C cg16165903 chr3:32023351 ZNF860;OSBPL10 0.65 6.29 0.32 9.64e-10 Lipoprotein (a) - cholesterol levels; LIHC cis rs11603020 0.904 rs11606677 chr11:57383377 G/A cg19752551 chr11:57585705 CTNND1 -0.46 -5.98 -0.31 5.62e-9 Blood protein levels; LIHC cis rs1005277 0.579 rs1621040 chr10:38497232 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.2 -0.32 1.63e-9 Extrinsic epigenetic age acceleration; LIHC cis rs875971 0.660 rs79009421 chr7:66068509 G/C cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.48e-14 Aortic root size; LIHC cis rs12586317 0.620 rs58320987 chr14:35587726 T/C cg05294307 chr14:35346193 BAZ1A -0.46 -6.72 -0.34 7.74e-11 Psoriasis; LIHC cis rs736408 0.648 rs2268023 chr3:52819327 T/A cg18404041 chr3:52824283 ITIH1 -0.59 -9.64 -0.46 1.31e-19 Bipolar disorder; LIHC cis rs2425143 1.000 rs8124505 chr20:34307247 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs9470366 0.527 rs4711456 chr6:36632482 C/T cg00935119 chr6:36647544 CDKN1A 0.46 6.51 0.33 2.6200000000000003e-10 QRS duration; LIHC cis rs6001982 0.541 rs6002000 chr22:41051109 G/A cg14879645 chr22:41048474 NA 0.4 5.8 0.3 1.53e-8 Breast cancer; LIHC cis rs7618501 0.521 rs6774354 chr3:49961780 G/A cg05623727 chr3:50126028 RBM5 0.34 5.79 0.3 1.61e-8 Intelligence (multi-trait analysis); LIHC cis rs7100689 0.646 rs4265545 chr10:82119271 G/T cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs7917772 0.636 rs1475644 chr10:104491164 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.53 6.37 0.33 6.06e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs763121 0.853 rs4821808 chr22:39065739 A/G cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs17539620 0.624 rs7770107 chr6:154836862 A/G cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.65 9.12 0.44 6.36e-18 Lymphocyte counts; LIHC cis rs7903847 0.642 rs2297668 chr10:99160046 C/T cg20016023 chr10:99160130 RRP12 -0.42 -6.68 -0.34 9.67e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs7223966 1.000 rs6504171 chr17:61710010 G/A cg05941027 chr17:61774174 LIMD2 0.31 6.19 0.32 1.69e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs709400 0.663 rs11623869 chr14:103883633 G/T cg26031613 chr14:104095156 KLC1 0.77 10.1 0.48 3.62e-21 Body mass index; LIHC cis rs875971 0.545 rs316316 chr7:65614257 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.38 -7.52 -0.38 5.01e-13 Aortic root size; LIHC cis rs4788570 0.615 rs11075894 chr16:71690030 C/T cg06353428 chr16:71660113 MARVELD3 1.44 15.51 0.64 1.81e-41 Intelligence (multi-trait analysis); LIHC cis rs2380220 0.808 rs2716072 chr6:95909773 A/G cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.47 -6.61 -0.34 1.5e-10 Electroencephalogram traits; LIHC cis rs35110281 0.805 rs2838318 chr21:44991825 G/A cg01579765 chr21:45077557 HSF2BP -0.32 -6.25 -0.32 1.19e-9 Mean corpuscular volume; LIHC cis rs9581857 0.685 rs11839899 chr13:28041780 G/A cg22138327 chr13:27999177 GTF3A 0.76 6.15 0.32 2.16e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02963556 chr12:132588637 EP400NL 0.42 6.11 0.31 2.76e-9 Immature fraction of reticulocytes; LIHC cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg20887711 chr4:1340912 KIAA1530 -0.49 -7.42 -0.37 9.47e-13 Obesity-related traits; LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg11965913 chr1:205819406 PM20D1 0.63 9.27 0.45 2.11e-18 Menarche (age at onset); LIHC cis rs17253792 0.822 rs75049893 chr14:56089158 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs3106136 0.843 rs724260 chr4:95260685 A/G cg11021082 chr4:95130006 SMARCAD1 0.41 7.31 0.37 1.85e-12 Capecitabine sensitivity; LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg11494091 chr17:61959527 GH2 0.35 5.82 0.3 1.34e-8 Height; LIHC cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg17971929 chr21:40555470 PSMG1 0.81 9.67 0.46 1.06e-19 Cognitive function; LIHC cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg18357526 chr6:26021779 HIST1H4A -0.88 -12.82 -0.57 5.58e-31 Intelligence (multi-trait analysis); LIHC cis rs9309473 0.948 rs7607892 chr2:73818707 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.54 -0.33 2.2e-10 Metabolite levels; LIHC cis rs4660261 0.526 rs2485996 chr1:44354661 C/T cg12908607 chr1:44402522 ARTN -0.48 -8.11 -0.4 9.04e-15 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.647 rs12903331 chr15:77168268 C/G cg03037974 chr15:76606532 NA -0.6 -10.09 -0.48 4.04e-21 Blood metabolite levels; LIHC cis rs10845606 0.781 rs7972866 chr12:12828320 C/T cg09462578 chr12:12878428 APOLD1 -0.46 -6.87 -0.35 2.99e-11 Systemic lupus erythematosus; LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg03526160 chr20:43586170 TOMM34 -0.42 -6.25 -0.32 1.19e-9 Gut microbiome composition (summer); LIHC cis rs6750047 0.549 rs151096 chr2:38316571 A/C cg07380506 chr2:38303506 CYP1B1 -0.45 -5.96 -0.31 6.12e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs6062302 0.522 rs13038448 chr20:62218453 C/T cg06363034 chr20:62225388 GMEB2 -0.43 -7.29 -0.37 2.13e-12 Glioblastoma; LIHC cis rs422249 0.512 rs174546 chr11:61569830 C/T cg07689907 chr11:61582574 FADS1 0.39 5.79 0.3 1.58e-8 Trans fatty acid levels; LIHC cis rs9372253 0.645 rs7753212 chr6:110700229 T/C cg01119278 chr6:110721349 DDO -0.32 -6.72 -0.34 7.49e-11 Platelet distribution width; LIHC cis rs2439831 0.867 rs2470134 chr15:43849886 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.6 -7.39 -0.37 1.13e-12 Lung cancer in ever smokers; LIHC cis rs6762 0.748 rs7928935 chr11:839127 G/A cg15787769 chr11:842744 TSPAN4;POLR2L -0.61 -7.32 -0.37 1.77e-12 Mean platelet volume; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg22528358 chr1:107598549 PRMT6 -0.67 -11.45 -0.53 6.46e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6840360 0.550 rs62327349 chr4:152627230 G/C cg22705602 chr4:152727874 NA -0.38 -6.95 -0.35 1.81e-11 Intelligence (multi-trait analysis); LIHC cis rs2795502 1.000 rs3121278 chr10:43375646 G/T cg20628663 chr10:43360327 NA 0.41 6.5 0.33 2.93e-10 Blood protein levels; LIHC cis rs68170813 0.559 rs11769527 chr7:106912948 C/T cg02696742 chr7:106810147 HBP1 -0.52 -6.01 -0.31 4.7e-9 Coronary artery disease; LIHC cis rs7520050 0.807 rs28844317 chr1:46209207 T/C cg03146154 chr1:46216737 IPP 0.48 8.08 0.4 1.12e-14 Red blood cell count;Reticulocyte count; LIHC trans rs1432089 0.773 rs2877574 chr4:171783865 T/C cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs2573652 0.723 rs2573655 chr15:100515709 A/C cg09918751 chr15:100517450 ADAMTS17 -0.9 -16.35 -0.66 8.55e-45 Height; LIHC cis rs34172651 0.517 rs7204288 chr16:24784531 A/G cg00152838 chr16:24741724 TNRC6A -0.49 -6.04 -0.31 4e-9 Intelligence (multi-trait analysis); LIHC cis rs748404 0.578 rs4547312 chr15:43632138 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.57 9.12 0.44 6.8e-18 Lung cancer; LIHC cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg12756686 chr19:29218302 NA 0.43 6.72 0.34 7.79e-11 Methadone dose in opioid dependence; LIHC cis rs9858542 0.953 rs9811982 chr3:49624377 A/C cg03060546 chr3:49711283 APEH -0.52 -7.01 -0.35 1.25e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1005277 0.579 rs2474584 chr10:38416389 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.82e-23 Extrinsic epigenetic age acceleration; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs736408 0.522 rs998909 chr3:52805093 A/G cg10802521 chr3:52805072 NEK4 -0.43 -7.01 -0.35 1.24e-11 Bipolar disorder; LIHC cis rs4478037 0.822 rs9865342 chr3:33118631 G/A cg27203090 chr3:33138513 GLB1;TMPPE -0.55 -6.91 -0.35 2.4e-11 Major depressive disorder; LIHC cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg18867708 chr6:26865862 GUSBL1 0.52 7.85 0.39 5.3e-14 Schizophrenia; LIHC cis rs2204008 0.745 rs8189516 chr12:38239084 C/T cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs57221529 0.766 rs12518859 chr5:587432 C/T cg09021430 chr5:549028 NA -0.45 -8.7 -0.43 1.45e-16 Lung disease severity in cystic fibrosis; LIHC cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.15 -0.48 2.55e-21 Platelet count; LIHC cis rs1577917 0.655 rs9444351 chr6:86247799 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.37 6.57 0.33 1.89e-10 Response to antipsychotic treatment; LIHC cis rs8062405 0.698 rs10499 chr16:28915527 G/A cg00204512 chr16:28754710 NA -0.37 -6.44 -0.33 4.15e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10089 1.000 rs4836369 chr5:127486462 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.74 0.34 6.93e-11 Ileal carcinoids; LIHC cis rs752010 0.668 rs10890147 chr1:42089725 A/T cg06885757 chr1:42089581 HIVEP3 0.5 7.44 0.37 8.06e-13 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs11971779 0.650 rs4732380 chr7:139126859 C/T cg07862535 chr7:139043722 LUC7L2 0.59 9.92 0.47 1.46e-20 Diisocyanate-induced asthma; LIHC cis rs861020 0.630 rs686582 chr1:210008673 A/C cg05527609 chr1:210001259 C1orf107 0.49 6.93 0.35 2.1e-11 Orofacial clefts; LIHC cis rs1008375 0.966 rs12509962 chr4:17680292 G/A cg02297831 chr4:17616191 MED28 0.41 6.64 0.34 1.23e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs34779708 0.897 rs34481177 chr10:35380913 C/T cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6722750 0.783 rs11125991 chr2:64387765 A/G cg22352474 chr2:64371530 PELI1 0.46 6.6 0.34 1.59e-10 Neuroticism; LIHC cis rs7216064 1.000 rs4791212 chr17:65975385 C/T cg12091567 chr17:66097778 LOC651250 -0.7 -9.89 -0.47 1.96e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6964587 0.626 rs7785941 chr7:91531024 T/C cg17063962 chr7:91808500 NA -0.6 -10.74 -0.5 2.18e-23 Breast cancer; LIHC trans rs208520 0.770 rs2224422 chr6:66883993 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.14 -0.4 7.54e-15 Exhaled nitric oxide output; LIHC cis rs2361718 0.522 rs11867921 chr17:78121170 G/T cg09238746 chr17:78121135 EIF4A3 -0.87 -13.78 -0.6 1.11e-34 Yeast infection; LIHC cis rs12701220 0.553 rs9639882 chr7:1133731 G/A cg00990874 chr7:1149470 C7orf50 -0.69 -9.88 -0.47 2.12e-20 Bronchopulmonary dysplasia; LIHC cis rs67311347 0.668 rs73071710 chr3:40288587 A/G cg18306943 chr3:40428807 ENTPD3 0.4 6.81 0.35 4.42e-11 Renal cell carcinoma; LIHC cis rs6456156 0.586 rs10946208 chr6:167459596 C/T cg07741184 chr6:167504864 NA 0.28 6.7 0.34 8.68e-11 Primary biliary cholangitis; LIHC cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg05590025 chr7:65112418 INTS4L2 -0.7 -7.31 -0.37 1.88e-12 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23894291 chr15:57025234 ZNF280D 0.49 6.8 0.35 4.66e-11 Lung function (FEV1/FVC); LIHC cis rs2952156 0.920 rs2941506 chr17:37833035 A/G cg00129232 chr17:37814104 STARD3 -0.52 -9.8 -0.47 3.72e-20 Asthma; LIHC cis rs1451375 0.617 rs2060763 chr7:50542359 G/A cg14593290 chr7:50529359 DDC -0.64 -10.27 -0.49 9.62e-22 Malaria; LIHC cis rs3824867 0.879 rs10769267 chr11:47460098 C/T cg20307385 chr11:47447363 PSMC3 0.58 7.78 0.39 8.74e-14 Mean corpuscular hemoglobin; LIHC cis rs11252926 0.673 rs7096559 chr10:499188 C/T cg16346588 chr10:242978 ZMYND11 0.37 5.73 0.3 2.18e-8 Psychosis in Alzheimer's disease; LIHC cis rs367615 0.918 rs10054960 chr5:108866448 C/A cg17395555 chr5:108820864 NA 0.35 7.14 0.36 5.67e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs2839186 0.585 rs2839154 chr21:47637760 C/T cg12516959 chr21:47718080 NA 0.4 6.69 0.34 9.26e-11 Testicular germ cell tumor; LIHC cis rs651907 0.535 rs12633089 chr3:101528763 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs8062405 0.755 rs56209193 chr16:28585636 C/T cg16576597 chr16:28551801 NUPR1 0.45 6.98 0.35 1.54e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg13271783 chr10:134563150 INPP5A -0.52 -6.54 -0.33 2.18e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs918629 0.530 rs1057963 chr5:95235748 G/C cg10483112 chr5:95245456 ELL2 -0.37 -6.77 -0.34 5.52e-11 IgG glycosylation; LIHC cis rs477692 0.637 rs10829598 chr10:131319774 C/G cg05714579 chr10:131428358 MGMT 0.41 6.71 0.34 7.86e-11 Response to temozolomide; LIHC cis rs7116495 1.000 rs10751193 chr11:71785356 A/C cg26138937 chr11:71823887 C11orf51 -0.78 -7.7 -0.38 1.45e-13 Severe influenza A (H1N1) infection; LIHC cis rs8060686 0.641 rs8060893 chr16:68191608 A/T cg05110241 chr16:68378359 PRMT7 -0.57 -6.31 -0.32 8.81e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs11696739 0.513 rs2209313 chr20:1599142 A/G cg15722679 chr20:1638393 SIRPG -0.53 -9.56 -0.46 2.35e-19 Mean platelet volume; LIHC cis rs916888 0.779 rs430685 chr17:44859148 T/C cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4803468 1.000 rs13344563 chr19:41945904 G/C cg14132834 chr19:41945861 ATP5SL 0.45 6.61 0.34 1.5e-10 Height; LIHC cis rs12586317 0.547 rs77780729 chr14:35496176 C/A cg05294307 chr14:35346193 BAZ1A -0.52 -7.66 -0.38 1.93e-13 Psoriasis; LIHC cis rs1451375 0.617 rs896307 chr7:50569060 T/C cg14593290 chr7:50529359 DDC -0.61 -9.94 -0.47 1.31e-20 Malaria; LIHC cis rs11190604 1.000 rs11190555 chr10:102209160 A/G cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg24549020 chr5:56110836 MAP3K1 0.51 6.49 0.33 2.95e-10 Initial pursuit acceleration; LIHC cis rs7727544 0.645 rs272857 chr5:131685297 G/A cg24060327 chr5:131705240 SLC22A5 -0.58 -8.5 -0.42 6.08e-16 Blood metabolite levels; LIHC cis rs5760092 0.572 rs738806 chr22:24234172 A/G cg16132339 chr22:24313637 DDTL;DDT 0.45 6.33 0.32 7.72e-10 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs6952808 0.609 rs4721190 chr7:1954732 A/G cg20295408 chr7:1910781 MAD1L1 0.5 7.26 0.37 2.61e-12 Bipolar disorder and schizophrenia; LIHC cis rs913351 0.826 rs633858 chr9:129725493 A/G cg14563165 chr9:130214037 LRSAM1;RPL12 0.87 6.22 0.32 1.48e-9 Lewy body disease; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg13409248 chr3:40428643 ENTPD3 0.47 7.75 0.39 1.04e-13 Renal cell carcinoma; LIHC cis rs7582180 0.652 rs11675901 chr2:100951189 G/A cg14675211 chr2:100938903 LONRF2 0.53 8.37 0.41 1.54e-15 Intelligence (multi-trait analysis); LIHC cis rs854765 0.647 rs712267 chr17:18021607 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.38 7.07 0.36 9.01e-12 Total body bone mineral density; LIHC cis rs4474465 1.000 rs11237511 chr11:78173606 C/T cg27205649 chr11:78285834 NARS2 -0.38 -5.97 -0.31 5.79e-9 Alzheimer's disease (survival time); LIHC cis rs2075371 1.000 rs8134 chr7:133974519 A/G cg20476274 chr7:133979776 SLC35B4 0.76 13.29 0.58 8.87e-33 Mean platelet volume; LIHC cis rs7116495 1.000 rs1939245 chr11:71742532 C/T cg26138937 chr11:71823887 C11orf51 -0.82 -8.15 -0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs7208859 0.623 rs9915546 chr17:29132144 G/T cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9790314 0.846 rs7627528 chr3:160990878 A/G cg03342759 chr3:160939853 NMD3 -0.79 -12.82 -0.57 5.32e-31 Morning vs. evening chronotype; LIHC cis rs651907 0.514 rs12636046 chr3:101434448 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.3 0.52 2.33e-25 Colorectal cancer; LIHC cis rs16854884 0.582 rs34402874 chr3:143643249 T/A cg06585982 chr3:143692056 C3orf58 0.58 7.58 0.38 3.23e-13 Economic and political preferences (feminism/equality); LIHC cis rs6450176 1.000 rs3776702 chr5:53305419 G/A ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.66 -0.62 4.37e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg18876405 chr7:65276391 NA 0.55 9.42 0.45 7.17e-19 Aortic root size; LIHC cis rs10771511 1 rs10771511 chr12:29437217 T/C cg14222432 chr12:29376421 FAR2 0.31 6.42 0.33 4.67e-10 Platelet distribution width; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg17258537 chr5:179401804 RNF130 0.43 6.28 0.32 1.01e-9 Bilirubin levels; LIHC cis rs694739 1.000 rs694739 chr11:64097233 A/G cg23796481 chr11:64053134 BAD;GPR137 0.61 8.35 0.41 1.77e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7116495 1.000 rs58991229 chr11:71839878 G/A cg26138937 chr11:71823887 C11orf51 0.83 8.2 0.41 4.93e-15 Severe influenza A (H1N1) infection; LIHC cis rs765787 0.530 rs13329228 chr15:45533017 C/T cg24006582 chr15:45444508 DUOX1 -0.53 -7.7 -0.38 1.5e-13 Uric acid levels; LIHC cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg25894440 chr7:65020034 NA -0.53 -5.96 -0.31 6.29e-9 Diabetic kidney disease; LIHC cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg24531977 chr5:56204891 C5orf35 -0.66 -9.4 -0.45 7.86e-19 Initial pursuit acceleration; LIHC cis rs9303401 0.659 rs17222691 chr17:56771096 C/T cg25039879 chr17:56429692 SUPT4H1 0.79 8.89 0.43 3.47e-17 Cognitive test performance; LIHC cis rs9457247 0.602 rs2157388 chr6:167481912 G/A cg12798992 chr6:167411361 FGFR1OP 0.46 6.72 0.34 7.71e-11 Crohn's disease; LIHC cis rs763014 0.932 rs2384972 chr16:674424 G/A cg00802000 chr16:706648 WDR90 -0.38 -6.22 -0.32 1.49e-9 Height; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs2242116 0.796 rs4587 chr3:46963502 T/C cg16586182 chr3:47516702 SCAP -0.4 -6.73 -0.34 7e-11 Birth weight; LIHC cis rs5758511 0.680 rs5758688 chr22:42662501 T/C cg20195005 chr22:42527684 CYP2D6 0.31 5.93 0.31 7.21e-9 Birth weight; LIHC cis rs7772486 0.754 rs857881 chr6:145970793 C/A cg13319975 chr6:146136371 FBXO30 0.41 6.76 0.34 6.12e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs713477 0.967 rs12887653 chr14:55911030 T/A cg13175173 chr14:55914753 NA -0.34 -8.03 -0.4 1.57e-14 Pediatric bone mineral content (femoral neck); LIHC cis rs4423214 0.592 rs7120029 chr11:71198957 G/A cg05163923 chr11:71159392 DHCR7 -0.58 -7.13 -0.36 5.98e-12 Vitamin D levels; LIHC cis rs3008870 1.000 rs11208976 chr1:67434411 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs6088590 0.735 rs2273684 chr20:33529766 G/T cg06115741 chr20:33292138 TP53INP2 -0.4 -5.76 -0.3 1.9e-8 Coronary artery disease; LIHC cis rs4975616 0.804 rs456366 chr5:1337070 T/C cg07493874 chr5:1342172 CLPTM1L -0.7 -11.23 -0.52 4.1e-25 Lung cancer; LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg26338869 chr17:61819248 STRADA 0.6 8.78 0.43 8.04e-17 Prudent dietary pattern; LIHC cis rs7208859 0.573 rs73277960 chr17:29177441 T/C cg13385521 chr17:29058706 SUZ12P 0.79 7.88 0.39 4.55e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs265548 0.608 rs36690 chr19:17910483 C/T cg16744531 chr19:17905626 B3GNT3 0.58 8.81 0.43 6.21e-17 Tumor biomarkers; LIHC cis rs6442522 0.671 rs2305616 chr3:15515695 C/T cg16303742 chr3:15540471 COLQ 0.39 6.53 0.33 2.33e-10 Uric acid levels; LIHC cis rs9322817 0.513 rs2499661 chr6:105300074 C/G cg02098413 chr6:105308735 HACE1 0.43 7.92 0.39 3.38e-14 Thyroid stimulating hormone; LIHC trans rs875971 0.545 rs11767262 chr7:65767224 T/A cg26939375 chr7:64535504 NA 0.41 6.48 0.33 3.12e-10 Aortic root size; LIHC cis rs919433 1.000 rs2889363 chr2:198163699 A/G cg03934865 chr2:198174659 NA -0.62 -10.27 -0.49 9.44e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9309473 1.000 rs6546837 chr2:73677898 G/C cg20560298 chr2:73613845 ALMS1 -0.54 -6.83 -0.35 3.84e-11 Metabolite levels; LIHC cis rs1707322 0.721 rs11211157 chr1:46132844 T/C cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs950169 0.544 rs62021193 chr15:85170583 C/G cg12863693 chr15:85201151 NMB 0.49 7.11 0.36 6.72e-12 Schizophrenia; LIHC cis rs637571 0.522 rs649000 chr11:65742933 T/C cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.94 0.31 6.97e-9 Eosinophil percentage of white cells; LIHC cis rs8177179 0.967 rs4078166 chr3:133435979 C/A cg16262614 chr3:133464971 TF 0.46 10.39 0.49 3.84e-22 Iron status biomarkers (transferrin levels); LIHC trans rs12310956 0.515 rs1852221 chr12:33945489 G/T cg26384229 chr12:38710491 ALG10B 0.47 6.55 0.33 2.1e-10 Morning vs. evening chronotype; LIHC cis rs10791097 0.694 rs4370948 chr11:130755700 A/C cg22079354 chr11:130786696 SNX19 0.41 5.92 0.3 7.84e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs8002861 0.840 rs7989353 chr13:44438957 T/C cg17145862 chr1:211918768 LPGAT1 0.58 10.69 0.5 3.33e-23 Leprosy; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg05896524 chr21:47604654 C21orf56 -0.49 -7.82 -0.39 6.58e-14 Testicular germ cell tumor; LIHC cis rs17001868 0.568 rs9611310 chr22:40733777 A/G cg07138101 chr22:40742427 ADSL 0.56 6.55 0.33 2.06e-10 Mammographic density (dense area); LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg11342453 chr6:26196699 NA 0.53 5.92 0.3 7.83e-9 Gout;Renal underexcretion gout; LIHC cis rs2842992 0.789 rs2842969 chr6:160145364 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.3 0.55 4.96e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs631288 0.793 rs6681716 chr1:146707824 A/C cg25205988 chr1:146714368 CHD1L 0.7 7.94 0.39 2.98e-14 PR interval in Tripanosoma cruzi seropositivity; LIHC cis rs9420 0.884 rs589914 chr11:57661032 A/G cg19752551 chr11:57585705 CTNND1 0.47 6.63 0.34 1.3e-10 Schizophrenia; LIHC cis rs4919087 1.000 rs4919087 chr10:99072507 C/T cg25902810 chr10:99078978 FRAT1 -0.69 -10.69 -0.5 3.32e-23 Monocyte count; LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg04234412 chr22:24373322 LOC391322 -0.68 -9.62 -0.46 1.52e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7589728 0.748 rs35051888 chr2:88482258 G/A cg18490616 chr2:88469792 THNSL2 0.65 6.6 0.34 1.54e-10 Plasma clusterin levels; LIHC cis rs826838 0.967 rs1684414 chr12:39129553 A/G cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg02782426 chr3:40428986 ENTPD3 0.34 6.36 0.33 6.62e-10 Renal cell carcinoma; LIHC cis rs861020 0.771 rs629150 chr1:209998467 C/T cg05527609 chr1:210001259 C1orf107 1.01 15.55 0.64 1.32e-41 Orofacial clefts; LIHC cis rs311392 0.554 rs369839 chr8:55097431 A/C cg20636351 chr8:55087400 NA -0.36 -7.31 -0.37 1.87e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs77861329 1.000 rs9843299 chr3:52137469 G/T cg08692210 chr3:52188851 WDR51A 0.83 7.55 0.38 4.05e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs7116495 0.609 rs10793014 chr11:71698838 A/G cg07596299 chr11:71824057 C11orf51 -0.75 -5.72 -0.3 2.3e-8 Severe influenza A (H1N1) infection; LIHC cis rs7940866 0.874 rs7111478 chr11:130819628 A/G cg12179176 chr11:130786555 SNX19 0.52 7.48 0.37 6.35e-13 Schizophrenia; LIHC cis rs8180040 0.764 rs11708451 chr3:47198826 G/A cg16586182 chr3:47516702 SCAP -0.5 -8.93 -0.43 2.66e-17 Colorectal cancer; LIHC cis rs3849570 0.643 rs11705789 chr3:81969196 G/T cg07356753 chr3:81810745 GBE1 -0.52 -7.99 -0.4 2.15e-14 Waist circumference;Body mass index; LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg12516959 chr21:47718080 NA 0.37 6.14 0.32 2.3e-9 Testicular germ cell tumor; LIHC cis rs13191362 1.000 rs34697913 chr6:163000187 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs3780486 0.505 rs10217267 chr9:33146528 T/C cg04842962 chr6:43655489 MRPS18A 0.8 15.12 0.63 6.51e-40 IgG glycosylation; LIHC cis rs7582720 1.000 rs72932786 chr2:203698737 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs595982 0.510 rs3826817 chr19:49401444 C/T cg21252483 chr19:49399788 TULP2 -0.6 -9.52 -0.46 3.25e-19 Red cell distribution width; LIHC cis rs7216064 0.953 rs80135947 chr17:65836001 A/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.34 -0.45 1.31e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs4919087 0.590 rs7915926 chr10:99054052 C/T cg25902810 chr10:99078978 FRAT1 -0.64 -7.08 -0.36 8.39e-12 Monocyte count; LIHC trans rs3780486 0.881 rs10738906 chr9:33135634 T/C cg04842962 chr6:43655489 MRPS18A 1.08 25.4 0.81 1.05e-80 IgG glycosylation; LIHC cis rs7618501 0.633 rs11130228 chr3:50003246 C/T cg24110177 chr3:50126178 RBM5 -0.46 -7.53 -0.38 4.48e-13 Intelligence (multi-trait analysis); LIHC cis rs7572733 0.534 rs10211202 chr2:198771941 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.84 0.35 3.69e-11 Dermatomyositis; LIHC cis rs6429082 0.782 rs704705 chr1:235612320 C/T cg26050004 chr1:235667680 B3GALNT2 -0.47 -7.11 -0.36 6.91e-12 Adiposity; LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg20607798 chr8:58055168 NA 0.66 8.39 0.41 1.26e-15 Developmental language disorder (linguistic errors); LIHC trans rs7615952 0.736 rs11921945 chr3:125643719 A/G cg07211511 chr3:129823064 LOC729375 -0.82 -10.24 -0.48 1.2e-21 Blood pressure (smoking interaction); LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg02993280 chr1:107599747 PRMT6 -0.61 -9.76 -0.47 5.01e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs28374715 0.662 rs72737793 chr15:41516823 C/T cg18705301 chr15:41695430 NDUFAF1 -0.85 -9.57 -0.46 2.24e-19 Ulcerative colitis; LIHC cis rs2839186 1.000 rs2839186 chr21:47690068 C/T cg05896524 chr21:47604654 C21orf56 0.46 7.01 0.35 1.32e-11 Testicular germ cell tumor; LIHC trans rs1814175 0.791 rs1722011 chr11:49899340 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg06873352 chr17:61820015 STRADA 0.61 9.44 0.45 6.16e-19 Height; LIHC cis rs10751667 0.666 rs6597966 chr11:950750 T/C cg06064525 chr11:970664 AP2A2 -0.56 -15.01 -0.63 1.81e-39 Alzheimer's disease (late onset); LIHC cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg25072359 chr17:41440525 NA 0.36 5.76 0.3 1.89e-8 Menopause (age at onset); LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg01339444 chr6:118972232 C6orf204 0.59 5.82 0.3 1.32e-8 Diastolic blood pressure; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08326511 chr2:120124503 C2orf76;DBI -0.45 -6.04 -0.31 4.11e-9 Hepatitis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21250466 chr4:854474 GAK -0.41 -6.09 -0.31 2.95e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.57 -0.5 8.62e-23 Platelet count; LIHC cis rs7613875 0.578 rs2624822 chr3:50107219 T/C cg21467203 chr3:49911342 NA 0.52 9.35 0.45 1.18e-18 Body mass index; LIHC cis rs10779751 0.770 rs1057079 chr1:11205058 A/G cg08854313 chr1:11322531 MTOR -0.86 -14.42 -0.62 3.58e-37 Body mass index; LIHC cis rs3789045 0.707 rs61421373 chr1:204560440 C/T cg17419461 chr1:204415978 PIK3C2B -0.39 -6.23 -0.32 1.39e-9 Educational attainment (college completion); LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs951366 0.576 rs1832775 chr1:205734032 C/T cg17723122 chr1:205641542 SLC45A3 0.38 5.75 0.3 1.99e-8 Menarche (age at onset); LIHC cis rs11628318 0.614 rs8013886 chr14:103117389 A/G cg12046867 chr14:103022105 NA 0.43 6.71 0.34 8e-11 Platelet count; LIHC cis rs1941023 0.606 rs7926219 chr11:60180335 C/T cg08716584 chr11:60157161 MS4A7 -0.32 -7.07 -0.36 8.52e-12 Congenital heart disease (maternal effect); LIHC cis rs10751667 0.600 rs10902266 chr11:1005697 G/T cg10932868 chr11:921992 NA 0.34 6.35 0.32 6.92e-10 Alzheimer's disease (late onset); LIHC cis rs910316 0.737 rs175049 chr14:75481368 C/T cg11812906 chr14:75593930 NEK9 -0.72 -13.44 -0.59 2.39e-33 Height; LIHC cis rs7927771 0.864 rs112060627 chr11:47426956 G/A cg18512352 chr11:47633146 NA -0.25 -5.87 -0.3 1.05e-8 Subjective well-being; LIHC cis rs6918586 0.615 rs198841 chr6:26111671 G/T cg18357526 chr6:26021779 HIST1H4A -0.56 -8.22 -0.41 4.13e-15 Schizophrenia; LIHC cis rs12477438 0.520 rs2632283 chr2:99776000 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs1790761 0.667 rs11227837 chr11:67336424 A/T cg21734168 chr11:67353974 GSTP1 -0.28 -6.75 -0.34 6.38e-11 Mean corpuscular volume; LIHC cis rs2072499 1.000 rs2072499 chr1:156169610 A/G cg06970220 chr1:156163860 SLC25A44 0.48 5.72 0.3 2.37e-8 Testicular germ cell tumor; LIHC cis rs2806561 0.929 rs628096 chr1:23537676 C/G cg19743168 chr1:23544995 NA 0.42 7.97 0.4 2.39e-14 Height; LIHC cis rs11871801 0.541 rs4793090 chr17:40686342 G/A cg14558262 chr17:40713999 COASY -0.57 -8.83 -0.43 5.54e-17 Crohn's disease; LIHC cis rs7945718 0.805 rs11022510 chr11:12833262 G/A cg25843174 chr11:12811716 TEAD1 0.33 7.72 0.39 1.32e-13 Educational attainment (years of education); LIHC cis rs5769765 0.862 rs9616381 chr22:50312382 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs10463316 0.894 rs6880137 chr5:150755232 A/G cg03212797 chr5:150827313 SLC36A1 -0.43 -6.47 -0.33 3.48e-10 Metabolite levels (Pyroglutamine); LIHC cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.563 rs1737586 chr6:8535897 C/T cg21535247 chr6:8435926 SLC35B3 0.64 8.32 0.41 2.18e-15 Motion sickness; LIHC cis rs5753618 0.519 rs5997939 chr22:31677130 C/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs6500602 0.727 rs6500607 chr16:4503631 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.49 7.83 0.39 6.3e-14 Schizophrenia; LIHC cis rs875971 0.862 rs801194 chr7:66028495 T/C cg18252515 chr7:66147081 NA 0.45 6.59 0.34 1.62e-10 Aortic root size; LIHC cis rs4631830 0.720 rs12412140 chr10:51503977 T/C cg16070123 chr10:51489643 NA 0.38 6.03 0.31 4.15e-9 Prostate-specific antigen levels; LIHC cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg15691649 chr6:25882328 NA 0.8 11.02 0.51 2.29e-24 Blood metabolite levels; LIHC cis rs9611519 0.964 rs2092563 chr22:41592677 G/A cg03806693 chr22:41940476 POLR3H -0.71 -7.79 -0.39 8.22e-14 Neuroticism; LIHC cis rs1707322 0.717 rs2991988 chr1:46082431 C/A cg03146154 chr1:46216737 IPP -0.56 -9.29 -0.45 1.79e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7945705 0.902 rs10769980 chr11:9014180 G/A cg12365402 chr11:9010492 NRIP3 0.34 8.64 0.42 2.23e-16 Hemoglobin concentration; LIHC cis rs11671005 0.651 rs35117909 chr19:58912906 G/A cg25952890 chr19:58913133 NA 0.7 7.2 0.36 3.96e-12 Mean platelet volume; LIHC cis rs9457247 0.602 rs9459854 chr6:167465882 C/T cg07741184 chr6:167504864 NA 0.36 8.32 0.41 2.16e-15 Crohn's disease; LIHC cis rs3008870 0.916 rs2025608 chr1:67422550 C/T cg02640540 chr1:67518911 SLC35D1 0.43 5.93 0.31 7.24e-9 Lymphocyte percentage of white cells; LIHC cis rs10751667 0.666 rs10902239 chr11:946484 A/G cg10932868 chr11:921992 NA -0.39 -7.37 -0.37 1.28e-12 Alzheimer's disease (late onset); LIHC cis rs600806 0.888 rs3879449 chr1:109904971 A/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs2280018 0.963 rs11075255 chr16:15166232 A/G cg07549590 chr16:15018862 NA -0.33 -6.28 -0.32 1.03e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9534288 0.797 rs6561280 chr13:46583691 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs208520 0.874 rs208491 chr6:66928459 C/G cg07460842 chr6:66804631 NA -0.78 -8.51 -0.42 5.6e-16 Exhaled nitric oxide output; LIHC cis rs10779751 0.770 rs4845853 chr1:11243470 A/G cg08854313 chr1:11322531 MTOR 0.84 14.74 0.62 2.06e-38 Body mass index; LIHC trans rs2537594 0.936 rs1404418 chr7:17814085 A/T cg21197435 chr1:23671362 HNRNPR 0.42 6.04 0.31 3.92e-9 Mean corpuscular hemoglobin; LIHC cis rs7666738 0.830 rs13148363 chr4:98847498 T/C cg05340658 chr4:99064831 C4orf37 0.65 11.71 0.54 7.1e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs1008375 1.000 rs4698641 chr4:17642630 C/T cg16339924 chr4:17578868 LAP3 0.43 5.94 0.31 6.95e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3741404 0.560 rs2875748 chr11:63915537 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.7 -10.46 -0.49 2.05e-22 Platelet count; LIHC cis rs7917772 0.619 rs2251772 chr10:104470918 T/C cg22532475 chr10:104410764 TRIM8 -0.38 -6.59 -0.34 1.66e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs933688 0.526 rs9293565 chr5:90609736 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.48 7.0 0.35 1.39e-11 Smoking behavior; LIHC cis rs2075371 0.863 rs34231360 chr7:133944988 A/C cg11752832 chr7:134001865 SLC35B4 0.46 5.95 0.31 6.52e-9 Mean platelet volume; LIHC cis rs1395 0.961 rs4665963 chr2:27528692 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.19 -0.32 1.72e-9 Blood metabolite levels; LIHC cis rs10979 0.928 rs6924967 chr6:143906235 C/T cg25407410 chr6:143891975 LOC285740 -0.37 -5.85 -0.3 1.15e-8 Hypospadias; LIHC cis rs2404602 0.735 rs11635463 chr15:76762986 C/T cg23625390 chr15:77176239 SCAPER -0.48 -8.03 -0.4 1.61e-14 Blood metabolite levels; LIHC cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg25894440 chr7:65020034 NA -0.56 -6.48 -0.33 3.21e-10 Diabetic kidney disease; LIHC cis rs748404 0.697 rs564946 chr15:43556272 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.28 0.41 2.8e-15 Lung cancer; LIHC cis rs8067545 0.586 rs11657161 chr17:20180715 A/G cg13482628 chr17:19912719 NA -0.41 -6.77 -0.34 5.57e-11 Schizophrenia; LIHC cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg06640241 chr16:89574553 SPG7 0.66 10.72 0.5 2.52e-23 Multiple myeloma (IgH translocation); LIHC cis rs9902453 0.845 rs3115099 chr17:28019293 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.81 0.54 3.07e-27 Coffee consumption (cups per day); LIHC cis rs5769765 0.908 rs138867 chr22:50207703 A/G cg02269571 chr22:50332266 NA 0.63 8.4 0.41 1.18e-15 Schizophrenia; LIHC cis rs9309473 1.000 rs10169714 chr2:73808773 T/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.5 -0.33 2.86e-10 Metabolite levels; LIHC trans rs11098499 0.644 rs7676296 chr4:120555687 A/G cg25214090 chr10:38739885 LOC399744 0.5 8.06 0.4 1.3e-14 Corneal astigmatism; LIHC cis rs1127311 1.000 rs9427094 chr1:154557685 C/T cg17218026 chr1:154582156 ADAR 0.33 6.35 0.32 6.96e-10 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs798554 1.000 rs798554 chr7:2759795 C/T cg19717773 chr7:2847554 GNA12 -0.41 -6.42 -0.33 4.43e-10 Height; LIHC cis rs782590 0.967 rs1823893 chr2:55788921 T/C cg03859395 chr2:55845619 SMEK2 0.85 15.1 0.63 7.58e-40 Metabolic syndrome; LIHC cis rs597539 0.652 rs1249474 chr11:68654774 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.74 10.99 0.51 2.93e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs561341 1.000 rs72825740 chr17:30338356 A/G cg20587970 chr11:113659929 NA -1.45 -12.12 -0.55 2.26e-28 Hip circumference adjusted for BMI; LIHC cis rs7020830 0.522 rs10814509 chr9:37111057 A/G cg14294708 chr9:37120828 ZCCHC7 0.69 12.85 0.57 4.29e-31 Schizophrenia; LIHC cis rs757110 0.902 rs2074310 chr11:17421886 T/C cg15432903 chr11:17409602 KCNJ11 0.62 9.27 0.45 2.11e-18 Type 2 diabetes; LIHC cis rs12701220 0.817 rs59471534 chr7:1085224 G/A cg16145915 chr7:1198662 ZFAND2A -0.3 -6.01 -0.31 4.72e-9 Bronchopulmonary dysplasia; LIHC cis rs2033711 0.840 rs3764533 chr19:58929194 A/G cg13877915 chr19:58951672 ZNF132 0.53 8.01 0.4 1.8e-14 Uric acid clearance; LIHC cis rs116095464 0.558 rs10056628 chr5:279512 G/A cg22857025 chr5:266934 NA -1.52 -15.89 -0.65 5.89e-43 Breast cancer; LIHC cis rs903552 1.000 rs12908310 chr15:102003635 A/G cg06707286 chr15:102010195 PCSK6 -0.44 -6.33 -0.32 7.48e-10 Diabetic kidney disease; LIHC cis rs9905704 0.647 rs2286299 chr17:57043367 T/G cg05425664 chr17:57184151 TRIM37 -0.44 -6.11 -0.31 2.64e-9 Testicular germ cell tumor; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02119073 chr17:77984409 TBC1D16 0.41 6.52 0.33 2.55e-10 Immature fraction of reticulocytes; LIHC cis rs9910055 0.593 rs58392387 chr17:42297889 A/G cg19774624 chr17:42201019 HDAC5 -0.42 -5.93 -0.31 7.55e-9 Total body bone mineral density; LIHC cis rs74233809 0.901 rs12416331 chr10:104928914 T/A cg03493300 chr10:104813866 CNNM2 0.45 5.85 0.3 1.14e-8 Birth weight; LIHC cis rs2279817 1.000 rs905389 chr1:18021406 T/C cg21791023 chr1:18019539 ARHGEF10L 0.63 8.77 0.43 8.59e-17 Neuroticism; LIHC cis rs6582630 0.513 rs1596446 chr12:38282160 C/T cg26384229 chr12:38710491 ALG10B -0.83 -10.62 -0.5 5.66e-23 Drug-induced liver injury (flucloxacillin); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24508996 chr1:16057163 PLEKHM2 -0.38 -6.05 -0.31 3.7e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7520050 0.966 rs4660321 chr1:46366760 A/G cg03146154 chr1:46216737 IPP -0.38 -6.27 -0.32 1.11e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11864453 0.612 rs11862813 chr16:72132356 C/T cg01557791 chr16:72042693 DHODH -0.43 -7.11 -0.36 6.79e-12 Fibrinogen levels; LIHC cis rs2439831 0.681 rs956391 chr15:43617493 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.72 -10.35 -0.49 5.27e-22 Lung cancer in ever smokers; LIHC cis rs921968 0.643 rs526134 chr2:219402371 G/A cg02985541 chr2:219472218 PLCD4 0.45 8.68 0.42 1.62e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg22168489 chr12:122356033 WDR66 0.46 6.52 0.33 2.53e-10 Mean corpuscular volume; LIHC cis rs6977660 0.714 rs7798760 chr7:19803487 T/C cg07541023 chr7:19748670 TWISTNB 0.4 5.85 0.3 1.13e-8 Thyroid stimulating hormone; LIHC cis rs4788570 0.615 rs7193549 chr16:71649416 T/C cg06353428 chr16:71660113 MARVELD3 1.45 15.74 0.65 2.22e-42 Intelligence (multi-trait analysis); LIHC cis rs7617773 0.780 rs3197223 chr3:48335857 C/T cg11946769 chr3:48343235 NME6 0.93 11.77 0.54 4.3e-27 Coronary artery disease; LIHC cis rs7572733 0.534 rs700680 chr2:198707950 A/T cg03934865 chr2:198174659 NA -0.46 -6.69 -0.34 9.33e-11 Dermatomyositis; LIHC cis rs9381040 0.626 rs2272986 chr6:41037778 C/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.43 -6.69 -0.34 8.96e-11 Alzheimer's disease (late onset); LIHC cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg07424592 chr7:64974309 NA 0.81 9.2 0.45 3.52e-18 Diabetic kidney disease; LIHC cis rs12950390 0.814 rs11659069 chr17:45834275 G/T cg03474202 chr17:45855739 NA -0.35 -6.11 -0.31 2.75e-9 IgG glycosylation; LIHC cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg27572855 chr1:25598939 RHD 0.4 8.77 0.43 8.77e-17 Erythrocyte sedimentation rate; LIHC cis rs7542091 1.000 rs7542091 chr1:210031948 G/C cg22029157 chr1:209979665 IRF6 0.37 6.21 0.32 1.5e-9 Monobrow; LIHC cis rs8064024 0.599 rs882235 chr16:4931651 C/T cg08329684 chr16:4932620 PPL 0.35 5.9 0.3 8.87e-9 Cancer; LIHC cis rs67311347 0.955 rs60554147 chr3:40472503 T/C cg18306943 chr3:40428807 ENTPD3 0.34 6.06 0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs936229 0.749 rs4886633 chr15:75178207 G/A cg10253484 chr15:75165896 SCAMP2 -0.59 -6.94 -0.35 1.98e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs10791323 0.569 rs1944734 chr11:133720077 G/A cg06766960 chr11:133703094 NA -0.65 -10.94 -0.51 4.36e-24 Childhood ear infection; LIHC cis rs56104184 0.725 rs1466896 chr19:49385253 C/G cg21252483 chr19:49399788 TULP2 -1.06 -12.26 -0.55 6.67e-29 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs4908768 0.906 rs114812780 chr1:8528854 G/T cg25722041 chr1:8623473 RERE 0.41 5.86 0.3 1.11e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs12497850 0.931 rs7628719 chr3:48995487 C/T cg06212747 chr3:49208901 KLHDC8B 0.58 7.48 0.37 6.53e-13 Parkinson's disease; LIHC cis rs13161895 0.702 rs73810942 chr5:179499267 C/A cg06664874 chr5:179499304 RNF130 0.68 7.29 0.37 2.15e-12 LDL cholesterol; LIHC cis rs10779751 0.708 rs2746640 chr1:11292952 T/A cg08854313 chr1:11322531 MTOR 0.8 11.03 0.51 2.11e-24 Body mass index; LIHC cis rs965469 0.545 rs6051846 chr20:3403824 A/G cg25506879 chr20:3388711 C20orf194 0.48 6.37 0.33 6.24e-10 IFN-related cytopenia; LIHC cis rs9378688 0.654 rs2505658 chr6:2329626 C/T cg12303981 chr6:2244766 GMDS -0.45 -6.08 -0.31 3.2e-9 Caudate nucleus volume; LIHC cis rs1552244 0.572 rs3894321 chr3:10168892 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.59 -0.5 7.37e-23 Alzheimer's disease; LIHC cis rs13394619 1.000 rs4669752 chr2:11727988 G/C cg07314298 chr2:11723111 GREB1 -0.49 -9.29 -0.45 1.82e-18 Endometriosis; LIHC cis rs67311347 0.956 rs11714871 chr3:40428938 T/G cg13409248 chr3:40428643 ENTPD3 0.39 6.31 0.32 8.42e-10 Renal cell carcinoma; LIHC cis rs11583043 1.000 rs3861734 chr1:101489461 A/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.06 0.31 3.55e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9303401 0.659 rs61291849 chr17:56909867 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.28 0.55 5.86e-29 Cognitive test performance; LIHC cis rs113601626 1 rs113601626 chr2:24239189 T/TCCTGGC cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte percentage of white cells; LIHC cis rs950169 0.922 rs12910334 chr15:84958318 G/A cg03959625 chr15:84868606 LOC388152 0.48 6.75 0.34 6.18e-11 Schizophrenia; LIHC cis rs2834188 1.000 rs4408796 chr21:34698741 C/G cg14352951 chr21:34696688 IFNAR1 -0.48 -6.65 -0.34 1.16e-10 Narcolepsy; LIHC cis rs13108904 0.539 rs11247997 chr4:1361057 T/C cg00684032 chr4:1343700 KIAA1530 0.6 8.33 0.41 1.95e-15 Obesity-related traits; LIHC cis rs155076 1.000 rs58519241 chr13:21845006 C/A cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.3e-30 White matter hyperintensity burden; LIHC cis rs1008375 1.000 rs2315560 chr4:17677305 C/G cg02297831 chr4:17616191 MED28 0.42 6.69 0.34 9.02e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs13191362 1.000 rs73035025 chr6:163000988 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs826838 0.616 rs7966266 chr12:38626138 G/A cg26384229 chr12:38710491 ALG10B -0.51 -7.08 -0.36 8.34e-12 Heart rate; LIHC cis rs6835098 0.962 rs10027704 chr4:174083107 T/C cg27433088 chr4:174089019 GALNT7 0.38 6.93 0.35 2.07e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg11764359 chr7:65958608 NA -0.56 -5.87 -0.3 1.03e-8 Diabetic kidney disease; LIHC cis rs1113500 0.933 rs61797345 chr1:108623728 G/A cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.92e-12 Growth-regulated protein alpha levels; LIHC trans rs208520 0.526 rs7776413 chr6:66783241 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.04 -20.23 -0.74 2.18e-60 Exhaled nitric oxide output; LIHC cis rs9828933 0.577 rs832193 chr3:63854445 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.85 11.3 0.52 2.24e-25 Type 2 diabetes; LIHC cis rs11031096 0.655 rs12275634 chr11:4211754 T/G cg18678763 chr11:4115507 RRM1 -0.41 -5.92 -0.3 7.73e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1580019 0.713 rs2122632 chr7:32524686 A/G cg07520158 chr7:32535189 LSM5;AVL9 -0.56 -8.16 -0.4 6.58e-15 Cognitive ability; LIHC cis rs10420951 0.617 rs74497531 chr19:18578178 G/A cg10790698 chr19:18539756 SSBP4 -0.42 -5.83 -0.3 1.25e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg23982607 chr1:1823379 GNB1 -0.68 -13.47 -0.59 1.73e-33 Body mass index; LIHC cis rs2404602 0.692 rs7169663 chr15:77192843 A/C cg03037974 chr15:76606532 NA 0.73 14.3 0.61 1.08e-36 Blood metabolite levels; LIHC cis rs10751667 1.000 rs4074232 chr11:977682 C/G cg06064525 chr11:970664 AP2A2 -0.5 -12.47 -0.56 1.14e-29 Alzheimer's disease (late onset); LIHC cis rs4819052 0.765 rs2838827 chr21:46656146 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.69 10.25 0.48 1.15e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6546550 0.803 rs10165883 chr2:70117015 C/T cg02498382 chr2:70120550 SNRNP27 -0.42 -6.84 -0.35 3.75e-11 Prevalent atrial fibrillation; LIHC trans rs17685 0.712 rs9800948 chr7:75810473 A/G cg19862616 chr7:65841803 NCRNA00174 0.89 17.95 0.7 3.24e-51 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4843747 0.671 rs4075998 chr16:88106776 G/A cg00677901 chr16:88017247 BANP 0.53 8.01 0.4 1.88e-14 Menopause (age at onset); LIHC cis rs9918079 0.542 rs1789 chr4:15664535 G/A cg21329975 chr4:15471214 CC2D2A -0.41 -6.13 -0.31 2.37e-9 Obesity-related traits; LIHC trans rs10497394 1.000 rs1435767 chr2:174299698 C/T cg03284310 chr10:124894415 HMX3 0.51 6.23 0.32 1.37e-9 Otitis media (chronic/recurrent); LIHC cis rs9322817 0.691 rs2486138 chr6:105290223 G/A cg02098413 chr6:105308735 HACE1 0.45 8.41 0.41 1.15e-15 Thyroid stimulating hormone; LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.12 0.55 2.24e-28 Height; LIHC cis rs780096 0.527 rs12471703 chr2:27738854 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -6.04 -0.31 3.95e-9 Total body bone mineral density; LIHC cis rs1577917 0.740 rs9353327 chr6:86394066 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.81 -0.43 6.52e-17 Response to antipsychotic treatment; LIHC cis rs2599510 0.811 rs2710615 chr2:32791222 A/T cg02381751 chr2:32503542 YIPF4 0.49 6.63 0.34 1.32e-10 Interleukin-18 levels; LIHC cis rs7520050 0.966 rs12049588 chr1:46472422 G/A cg03146154 chr1:46216737 IPP -0.38 -6.21 -0.32 1.5e-9 Red blood cell count;Reticulocyte count; LIHC cis rs13191362 1.000 rs7769686 chr6:163199467 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.81 6.79 0.34 4.99e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs7714584 1.000 rs10065172 chr5:150227998 C/T cg20675040 chr8:143813288 C8orf55 0.34 6.06 0.31 3.59e-9 Crohn's disease; LIHC cis rs3749237 0.595 rs885592 chr3:49497883 T/G cg03060546 chr3:49711283 APEH 0.63 10.41 0.49 3.16e-22 Resting heart rate; LIHC cis rs2286885 0.965 rs4837092 chr9:129250251 T/C cg15282417 chr9:129245246 FAM125B 0.38 6.2 0.32 1.66e-9 Intraocular pressure; LIHC cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg05368731 chr17:41323189 NBR1 0.72 12.48 0.56 9.96e-30 Menopause (age at onset); LIHC cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg13395646 chr4:1353034 KIAA1530 -0.52 -8.66 -0.42 1.9e-16 Obesity-related traits; LIHC cis rs7116495 1.000 rs610041 chr11:71797968 A/G cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC trans rs6600671 0.934 rs12131379 chr1:121293437 T/C cg09829573 chr1:144692074 NBPF9 -0.41 -7.38 -0.37 1.23e-12 Hip geometry; LIHC cis rs9457247 0.534 rs12055488 chr6:167379570 A/G cg12798992 chr6:167411361 FGFR1OP -0.45 -7.28 -0.37 2.24e-12 Crohn's disease; LIHC cis rs6547741 1.000 rs6547740 chr2:27854369 C/T cg27432699 chr2:27873401 GPN1 0.63 10.05 0.48 5.47e-21 Oral cavity cancer; LIHC cis rs1997103 1.000 rs2877284 chr7:55408778 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1355223 0.816 rs2136506 chr11:34748260 T/C cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.46 -0.33 3.61e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2933343 0.953 rs2933344 chr3:128658715 A/G cg25356066 chr3:128598488 ACAD9 0.52 6.98 0.35 1.5e-11 IgG glycosylation; LIHC cis rs7927771 0.524 rs7111576 chr11:47787445 G/A cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs6762477 0.748 rs11711407 chr3:50225029 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.57 -9.29 -0.45 1.85e-18 Menarche (age at onset); LIHC cis rs174601 0.861 rs174581 chr11:61606683 G/A cg27386326 chr11:61587980 NA 0.68 14.61 0.62 6.93e-38 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg02931644 chr1:25747376 RHCE 0.38 8.44 0.42 9.06e-16 Erythrocyte sedimentation rate; LIHC cis rs490234 0.719 rs13287525 chr9:128219180 T/C cg14078157 chr9:128172775 NA -0.37 -6.34 -0.32 7.33e-10 Mean arterial pressure; LIHC cis rs2404602 0.692 rs72738889 chr15:76992063 G/A cg03037974 chr15:76606532 NA 0.74 14.52 0.62 1.55e-37 Blood metabolite levels; LIHC cis rs4319547 0.956 rs10773302 chr12:123043145 G/T cg23029597 chr12:123009494 RSRC2 -0.53 -7.46 -0.37 7.05e-13 Body mass index; LIHC cis rs709400 0.894 rs10143293 chr14:104063014 G/A cg26031613 chr14:104095156 KLC1 1.13 14.81 0.63 1.06e-38 Body mass index; LIHC cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs2070488 1.000 rs1002676 chr3:38444932 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.88 -14.54 -0.62 1.22e-37 Electrocardiographic conduction measures; LIHC cis rs5769765 0.704 rs138837 chr22:50180714 A/G cg02269571 chr22:50332266 NA -0.56 -7.71 -0.38 1.4e-13 Schizophrenia; LIHC cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg03735888 chr19:58951602 ZNF132 0.4 6.97 0.35 1.67e-11 Uric acid clearance; LIHC cis rs72781680 1.000 rs72796358 chr2:24160132 T/A cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs7954584 0.520 rs1169096 chr12:122465836 G/C cg22168489 chr12:122356033 WDR66 -0.36 -5.89 -0.3 9.4e-9 Mean corpuscular volume; LIHC cis rs4654899 0.785 rs12070677 chr1:21337322 A/G cg08539965 chr1:21396338 EIF4G3 0.33 5.87 0.3 1.04e-8 Superior frontal gyrus grey matter volume; LIHC cis rs908922 0.676 rs525960 chr1:152497866 T/A cg20991723 chr1:152506922 NA 0.59 10.51 0.49 1.45e-22 Hair morphology; LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg13409248 chr3:40428643 ENTPD3 0.49 8.22 0.41 4.34e-15 Renal cell carcinoma; LIHC cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg10295955 chr4:187884368 NA -0.96 -22.24 -0.77 2.12e-68 Lobe attachment (rater-scored or self-reported); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13148511 chr17:4710380 PLD2 -0.46 -6.32 -0.32 8.1e-10 Systolic blood pressure; LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg02782426 chr3:40428986 ENTPD3 0.33 6.19 0.32 1.76e-9 Renal cell carcinoma; LIHC cis rs1707322 0.721 rs28817701 chr1:46186050 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs61990749 0.544 rs12435761 chr14:78246077 C/G cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.26 0.49 1e-21 Fibroblast growth factor basic levels; LIHC trans rs743793 0.875 rs137379 chr22:33578150 T/C cg20274824 chr1:36638199 MAP7D1 0.46 6.42 0.33 4.66e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs11971779 0.590 rs4732374 chr7:139091453 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs3762637 1.000 rs9833415 chr3:122159840 G/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg09455208 chr3:40491958 NA 0.39 7.79 0.39 8.31e-14 Renal cell carcinoma; LIHC trans rs11148252 0.583 rs9536048 chr13:52958788 T/C cg18335740 chr13:41363409 SLC25A15 0.38 6.31 0.32 8.73e-10 Lewy body disease; LIHC cis rs1707322 0.691 rs12031182 chr1:46220999 C/T cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs5762813 0.566 rs28360615 chr22:29338656 G/C cg15103426 chr22:29168792 CCDC117 0.43 6.04 0.31 3.93e-9 Hematocrit;Hemoglobin concentration; LIHC cis rs116095464 0.558 rs56127718 chr5:270273 G/T cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC trans rs78049276 0.736 rs6841473 chr4:148407652 C/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.58 -7.06 -0.36 9.43e-12 Pulse pressure; LIHC cis rs838721 1.000 rs838717 chr2:234296444 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 -0.4 -5.82 -0.3 1.33e-8 Total body bone mineral density; LIHC cis rs67478160 0.643 rs11628332 chr14:104241141 C/T cg08213375 chr14:104286397 PPP1R13B 0.64 12.74 0.57 1.08e-30 Schizophrenia; LIHC cis rs1790761 0.692 rs674783 chr11:67339076 C/T cg00290607 chr11:67383545 NA 0.38 5.77 0.3 1.77e-8 Mean corpuscular volume; LIHC cis rs7772486 0.719 rs4391282 chr6:146276780 A/T cg23711669 chr6:146136114 FBXO30 -0.61 -10.66 -0.5 4.1000000000000003e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7095944 0.582 rs2303611 chr10:126517989 G/A cg08799069 chr10:126477246 METTL10 -0.4 -7.26 -0.37 2.59e-12 Asthma; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.23 -0.32 1.36e-9 Total body bone mineral density; LIHC cis rs10791097 0.667 rs1893019 chr11:130756664 C/G cg22079354 chr11:130786696 SNX19 0.41 5.82 0.3 1.35e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs8177876 0.915 rs6420418 chr16:81128014 G/T cg19254163 chr11:60623782 GPR44 -0.46 -6.04 -0.31 3.96e-9 Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid); LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg06656553 chr16:89960601 TCF25 -0.49 -6.18 -0.32 1.86e-9 Skin colour saturation; LIHC cis rs965469 1.000 rs6051718 chr20:3270370 C/T cg25506879 chr20:3388711 C20orf194 -0.6 -6.91 -0.35 2.43e-11 IFN-related cytopenia; LIHC cis rs894734 0.535 rs2366143 chr12:54323256 G/A cg17708016 chr12:54321992 NA 0.42 7.17 0.36 4.8e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs7131987 0.650 rs11050187 chr12:29472876 T/C cg16970926 chr12:29381810 FAR2 0.29 6.01 0.31 4.78e-9 QT interval; LIHC cis rs3806843 0.648 rs702399 chr5:140024432 C/T cg16179182 chr5:140090404 VTRNA1-1 0.37 6.03 0.31 4.26e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9921222 1.000 rs10794639 chr16:377367 A/G cg26944245 chr16:421049 TMEM8A;MRPL28 0.37 6.42 0.33 4.5e-10 Bone mineral density (spine);Bone mineral density; LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.71 11.59 0.53 1.98e-26 Prudent dietary pattern; LIHC cis rs9914988 0.943 rs2874253 chr17:27157863 A/T cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs5769765 0.908 rs56351880 chr22:50316597 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.26 -0.45 2.39e-18 Schizophrenia; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs6456156 0.586 rs9457261 chr6:167467679 A/G cg07741184 chr6:167504864 NA 0.29 6.98 0.35 1.52e-11 Primary biliary cholangitis; LIHC cis rs2279817 1.000 rs2354290 chr1:18019861 A/G cg21791023 chr1:18019539 ARHGEF10L 0.43 6.34 0.32 7.21e-10 Neuroticism; LIHC cis rs12220238 1.000 rs7905536 chr10:75997209 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.6 0.34 1.59e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg12463550 chr7:65579703 CRCP -0.67 -7.04 -0.36 1.06e-11 Diabetic kidney disease; LIHC cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.87 0.35 3.14e-11 Gut microbiome composition (summer); LIHC cis rs10508774 0.810 rs11008937 chr10:32728750 A/T cg01819863 chr10:32635814 EPC1 0.61 5.87 0.3 1.03e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg18357526 chr6:26021779 HIST1H4A -0.59 -8.4 -0.41 1.22e-15 Blood metabolite levels; LIHC cis rs10193935 0.901 rs1496329 chr2:42688797 T/C cg27598129 chr2:42591480 NA 0.7 8.86 0.43 4.55e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs1577917 0.740 rs2758843 chr6:86328431 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.47 -9.17 -0.44 4.37e-18 Response to antipsychotic treatment; LIHC cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg08499158 chr17:42289980 UBTF -0.52 -8.44 -0.42 9.17e-16 Total body bone mineral density; LIHC cis rs6701037 0.748 rs10912901 chr1:175138602 G/A cg00958927 chr1:175162553 KIAA0040 -0.39 -6.34 -0.32 7.27e-10 Alcohol dependence; LIHC cis rs6752107 0.967 rs2880080 chr2:234154139 G/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.53 7.97 0.4 2.47e-14 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10791097 0.694 rs2155749 chr11:130751094 G/T cg09137382 chr11:130731461 NA 0.42 6.26 0.32 1.18e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs3849570 0.555 rs4452351 chr3:82007977 C/T cg07356753 chr3:81810745 GBE1 -0.43 -6.51 -0.33 2.64e-10 Waist circumference;Body mass index; LIHC cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg08888203 chr3:10149979 C3orf24 0.63 7.0 0.35 1.36e-11 Alzheimer's disease; LIHC cis rs4919087 0.590 rs1088187 chr10:99027581 T/C cg25902810 chr10:99078978 FRAT1 -0.57 -6.32 -0.32 7.96e-10 Monocyte count; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs7072216 0.763 rs6584200 chr10:100170037 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.33 -0.32 7.8e-10 Metabolite levels; LIHC cis rs941873 0.772 rs1316312 chr10:81110417 G/C cg09469691 chr10:81107165 PPIF 0.7 10.58 0.5 8.1e-23 Height; LIHC trans rs2749592 0.550 rs4934881 chr10:37914346 A/C cg23533926 chr12:111358616 MYL2 0.33 6.37 0.33 6.13e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2439831 0.867 rs12323999 chr15:43683115 T/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 16.18 0.66 4.04e-44 Lung cancer in ever smokers; LIHC cis rs10540 1.000 rs12801271 chr11:508720 C/T cg03352830 chr11:487213 PTDSS2 0.81 6.87 0.35 3.02e-11 Body mass index; LIHC cis rs1005277 0.579 rs1740732 chr10:38491385 C/T cg00409905 chr10:38381863 ZNF37A -0.54 -9.04 -0.44 1.23e-17 Extrinsic epigenetic age acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20979128 chr1:16271176 ZBTB17 0.45 6.74 0.34 6.77e-11 Longevity; LIHC cis rs875971 0.862 rs9791712 chr7:66105163 C/G cg11764359 chr7:65958608 NA -0.76 -12.73 -0.57 1.14e-30 Aortic root size; LIHC cis rs9517302 0.847 rs9517297 chr13:99094961 A/C cg22223119 chr13:99095684 FARP1 -0.74 -12.11 -0.55 2.39e-28 Obesity-related traits; LIHC trans rs2727020 0.521 rs7107178 chr11:49526668 G/A cg03929089 chr4:120376271 NA 0.7 10.22 0.48 1.4e-21 Coronary artery disease; LIHC trans rs62103177 0.564 rs1864529 chr18:77748975 G/A cg05926928 chr17:57297772 GDPD1 -0.7 -7.87 -0.39 4.73e-14 Opioid sensitivity; LIHC cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg23262073 chr20:60523788 NA -0.28 -5.75 -0.3 2e-8 Body mass index; LIHC cis rs6918586 0.658 rs198814 chr6:26127759 A/G cg18357526 chr6:26021779 HIST1H4A -0.57 -8.63 -0.42 2.43e-16 Schizophrenia; LIHC cis rs9399135 0.967 rs4896123 chr6:135295410 T/G cg24558204 chr6:135376177 HBS1L 0.39 6.46 0.33 3.58e-10 Red blood cell count; LIHC cis rs10751667 0.666 rs7396509 chr11:956761 G/A cg06064525 chr11:970664 AP2A2 -0.56 -15.03 -0.63 1.52e-39 Alzheimer's disease (late onset); LIHC cis rs4948275 0.530 rs2139778 chr10:63134943 A/T cg03237606 chr10:63212265 TMEM26 0.29 6.35 0.32 6.95e-10 Night sleep phenotypes; LIHC cis rs10870270 0.957 rs3829156 chr10:133789386 C/G cg26149184 chr10:133730230 NA 0.5 7.95 0.39 2.74e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5758511 0.508 rs58099562 chr22:42453772 T/C cg00645731 chr22:42541494 CYP2D7P1 0.58 5.87 0.3 1.05e-8 Birth weight; LIHC cis rs7208859 0.623 rs12103508 chr17:29086781 T/G cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7903847 0.667 rs10882931 chr10:99165794 C/A cg06359132 chr10:99160096 RRP12 -0.37 -5.93 -0.31 7.28e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg21448741 chr8:58168803 NA 0.36 6.72 0.34 7.69e-11 Developmental language disorder (linguistic errors); LIHC cis rs425277 0.606 rs3128339 chr1:2046938 G/T cg04315214 chr1:2043799 PRKCZ 0.46 7.24 0.36 3.03e-12 Height; LIHC cis rs11792861 0.926 rs3750451 chr9:111822866 C/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.6 -0.34 1.55e-10 Menarche (age at onset); LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg11494091 chr17:61959527 GH2 0.36 6.05 0.31 3.82e-9 Height; LIHC cis rs7715806 0.500 rs34355 chr5:74959970 G/A cg07671805 chr5:74907694 NA -0.52 -6.32 -0.32 7.97e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs11039798 0.660 rs28435129 chr11:48629795 A/T cg15704280 chr7:45808275 SEPT13 0.59 6.58 0.34 1.8e-10 Axial length; LIHC cis rs7503807 1.000 rs7503807 chr17:78591111 G/T cg09596252 chr17:78655493 RPTOR -0.38 -6.68 -0.34 9.6e-11 Obesity; LIHC trans rs875971 1.000 rs6945843 chr7:65734783 G/A cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.15e-10 Aortic root size; LIHC cis rs7078219 0.505 rs10883373 chr10:101292484 G/A cg06854084 chr10:101292507 NKX2-3 -0.34 -6.22 -0.32 1.44e-9 Dental caries; LIHC cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg08219700 chr8:58056026 NA 0.52 6.08 0.31 3.27e-9 Developmental language disorder (linguistic errors); LIHC cis rs7659604 0.846 rs60340409 chr4:122666355 G/C cg19748678 chr4:122722346 EXOSC9 0.35 5.77 0.3 1.81e-8 Type 2 diabetes; LIHC trans rs4906332 1.000 rs28711288 chr14:103906126 T/C cg17675199 chr6:35436792 RPL10A 0.33 6.69 0.34 9.16e-11 Coronary artery disease; LIHC cis rs1113500 0.933 rs3909076 chr1:108631760 T/C cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.92e-12 Growth-regulated protein alpha levels; LIHC cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg20607798 chr8:58055168 NA 0.49 6.13 0.31 2.41e-9 Developmental language disorder (linguistic errors); LIHC cis rs2242116 0.760 rs4682845 chr3:46955404 G/C cg16586182 chr3:47516702 SCAP -0.39 -6.68 -0.34 9.89e-11 Birth weight; LIHC cis rs9649465 0.967 rs1506642 chr7:123390058 A/G cg03229431 chr7:123269106 ASB15 -0.38 -8.14 -0.4 7.19e-15 Migraine; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg18000306 chr6:288505 NA -0.33 -6.09 -0.31 3.1e-9 Menopause (age at onset); LIHC cis rs2832191 0.626 rs2254796 chr21:30341891 A/G cg08807101 chr21:30365312 RNF160 -0.78 -11.37 -0.52 1.27e-25 Dental caries; LIHC cis rs739401 0.611 rs3782069 chr11:3033275 G/A cg08508325 chr11:3079039 CARS -0.32 -6.93 -0.35 2.08e-11 Longevity; LIHC trans rs9747201 0.925 rs11867806 chr17:80072049 A/G cg07393940 chr7:158741817 NA -0.57 -6.87 -0.35 2.97e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2066819 1.000 rs75265219 chr12:56640341 G/A cg26734620 chr12:56694298 CS 1.23 10.54 0.5 1.14e-22 Psoriasis vulgaris; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.72 -12.37 -0.56 2.67e-29 Prudent dietary pattern; LIHC cis rs2197308 0.765 rs10880643 chr12:37926452 C/T cg26384229 chr12:38710491 ALG10B -0.47 -6.64 -0.34 1.23e-10 Morning vs. evening chronotype; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13878775 chr2:242041740 MTERFD2 -0.52 -6.17 -0.32 1.92e-9 Systolic blood pressure; LIHC cis rs7582720 1.000 rs72934518 chr2:203937908 T/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg09406631 chr2:209119940 IDH1 0.41 6.29 0.32 9.7e-10 Metabolic traits; LIHC cis rs12594515 1.000 rs8038320 chr15:45990267 G/C cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC cis rs679087 0.932 rs721617 chr12:29934586 C/T cg14258853 chr12:29935411 TMTC1 0.47 7.41 0.37 9.98e-13 Schizophrenia; LIHC cis rs2836950 0.545 rs2836940 chr21:40588696 T/C cg06238570 chr21:40685208 BRWD1 -0.43 -7.04 -0.36 1.05e-11 Menarche (age at onset); LIHC cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg20607798 chr8:58055168 NA 0.71 8.55 0.42 4.28e-16 Developmental language disorder (linguistic errors); LIHC cis rs929354 0.742 rs10251112 chr7:156963524 A/G cg16102536 chr7:156981717 UBE3C 0.35 5.9 0.3 8.51e-9 Body mass index; LIHC cis rs3213545 0.659 rs2259690 chr12:121457914 T/G cg02403541 chr12:121454288 C12orf43 0.68 13.04 0.58 8.03e-32 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs2115536 0.730 rs12898642 chr15:80182050 T/C cg00225070 chr15:80189496 MTHFS 0.59 9.64 0.46 1.28e-19 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.68e-17 Prudent dietary pattern; LIHC cis rs9790314 0.586 rs35713426 chr3:161131271 A/G cg03342759 chr3:160939853 NMD3 -0.56 -8.83 -0.43 5.44e-17 Morning vs. evening chronotype; LIHC trans rs6489882 0.867 rs7306205 chr12:113366899 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs6502050 0.865 rs56193110 chr17:80151501 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.97 -0.31 5.82e-9 Life satisfaction; LIHC cis rs1552244 0.572 rs12107622 chr3:10171898 T/A cg00149659 chr3:10157352 C3orf10 1.13 9.95 0.47 1.16e-20 Alzheimer's disease; LIHC cis rs1144333 0.850 rs1144341 chr1:76282659 T/G cg22875332 chr1:76189707 ACADM -0.42 -6.74 -0.34 6.7e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs703842 1.000 rs10877013 chr12:58165085 C/T cg18357645 chr12:58087776 OS9 -0.41 -6.41 -0.33 4.82e-10 Multiple sclerosis; LIHC trans rs9914544 0.545 rs7222748 chr17:18787976 T/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.57 -0.33 1.82e-10 Educational attainment (years of education); LIHC cis rs9328573 1.000 rs10468183 chr15:100512047 A/G cg09918751 chr15:100517450 ADAMTS17 -0.5 -7.67 -0.38 1.77e-13 Urate levels in lean individuals; LIHC cis rs4700695 1.000 rs111338 chr5:65420393 G/A cg21114390 chr5:65439923 SFRS12 -0.52 -7.03 -0.36 1.14e-11 Facial morphology (factor 19); LIHC cis rs7075426 0.646 rs4934210 chr10:88203667 G/A cg07322936 chr10:88137208 NA 0.48 6.31 0.32 8.53e-10 Migraine without aura; LIHC cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg25894440 chr7:65020034 NA 0.54 6.22 0.32 1.43e-9 Diabetic kidney disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24995352 chr10:13203403 MCM10 0.43 6.26 0.32 1.18e-9 Cognitive function; LIHC cis rs138341189 1 rs138341189 chr11:68224411 GATTGTGCCAAT/G cg16797656 chr11:68205561 LRP5 0.59 7.98 0.4 2.22e-14 Monobrow; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg03075683 chr16:11038168 CLEC16A -0.53 -6.44 -0.33 4.13e-10 Facial morphology (factor 20); LIHC cis rs763121 0.776 rs4820346 chr22:39125074 C/G cg14440974 chr22:39074834 NA 0.46 7.37 0.37 1.29e-12 Menopause (age at onset); LIHC cis rs17401966 1.000 rs12118323 chr1:10469641 A/G cg19773385 chr1:10388646 KIF1B -0.39 -6.31 -0.32 8.77e-10 Hepatocellular carcinoma; LIHC cis rs2279817 0.780 rs35588575 chr1:18007045 A/G cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.73 -0.39 1.2e-13 Neuroticism; LIHC cis rs1997103 1.000 rs4947500 chr7:55407270 C/A cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1113500 0.897 rs11185263 chr1:108639804 C/G cg06207961 chr1:108661230 NA 0.37 7.35 0.37 1.46e-12 Growth-regulated protein alpha levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12270129 chr12:121734046 CAMKK2 -0.42 -6.45 -0.33 3.79e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.46 -0.46 5.1e-19 Intelligence (multi-trait analysis); LIHC cis rs36051895 0.553 rs12338854 chr9:5057568 G/C cg02405213 chr9:5042618 JAK2 -0.73 -13.37 -0.59 4.31e-33 Pediatric autoimmune diseases; LIHC cis rs922107 0.713 rs359942 chr1:89975959 C/T cg15422784 chr1:90023713 LRRC8B 0.49 7.84 0.39 5.89e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs12980942 1.000 rs7257742 chr19:41827352 G/T cg25627403 chr19:41769009 HNRNPUL1 0.48 5.95 0.31 6.73e-9 Coronary artery disease; LIHC cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1419980 0.730 rs57772215 chr12:7746385 A/G cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs1577917 0.958 rs66807489 chr6:86440702 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.22 -0.41 4.25e-15 Response to antipsychotic treatment; LIHC cis rs2731664 0.792 rs335452 chr5:176879671 C/T cg23176889 chr5:176863531 GRK6 -0.72 -12.76 -0.57 9.29e-31 Intelligence (multi-trait analysis); LIHC cis rs1577917 1.000 rs12216203 chr6:86675301 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.77 -0.34 5.53e-11 Response to antipsychotic treatment; LIHC cis rs2075371 0.829 rs727202 chr7:133947942 A/G cg20476274 chr7:133979776 SLC35B4 0.69 9.35 0.45 1.19e-18 Mean platelet volume; LIHC cis rs1865721 0.771 rs72975986 chr18:73127649 A/G cg26385618 chr18:73139727 C18orf62 -0.32 -8.5 -0.42 6.16e-16 Intelligence; LIHC cis rs875971 0.660 rs13224319 chr7:66007363 A/G cg00343986 chr7:65444356 GUSB 0.4 6.05 0.31 3.88e-9 Aortic root size; LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg26304593 chr6:42947056 PEX6 -0.47 -6.05 -0.31 3.9e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs11122272 0.677 rs2808615 chr1:231550171 G/A cg06096015 chr1:231504339 EGLN1 -0.5 -9.35 -0.45 1.22e-18 Hemoglobin concentration; LIHC cis rs5769765 0.908 rs138891 chr22:50227741 G/A cg26441486 chr22:50317300 CRELD2 0.35 5.97 0.31 5.85e-9 Schizophrenia; LIHC cis rs7027203 0.797 rs4744294 chr9:96612114 C/G cg13679303 chr9:96623674 NA -0.29 -6.35 -0.32 6.72e-10 DNA methylation (variation); LIHC cis rs2404602 0.647 rs12910081 chr15:77022959 G/C cg03037974 chr15:76606532 NA -0.61 -10.28 -0.49 8.59e-22 Blood metabolite levels; LIHC cis rs539096 0.500 rs803678 chr1:44350898 G/T cg12908607 chr1:44402522 ARTN -0.48 -8.2 -0.41 4.91e-15 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.579 rs2474568 chr10:38383147 A/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.92 -0.3 8.02e-9 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs60871478 0.636 rs4721600 chr7:871728 C/T cg05535760 chr7:792225 HEATR2 -0.81 -6.54 -0.33 2.28e-10 Cerebrospinal P-tau181p levels; LIHC cis rs9682041 1.000 rs15709 chr3:170110529 T/A cg11886554 chr3:170076028 SKIL 0.72 6.23 0.32 1.38e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs8017423 0.935 rs3742667 chr14:90767856 T/C cg14092571 chr14:90743983 NA 0.44 6.91 0.35 2.37e-11 Mortality in heart failure; LIHC trans rs3780486 0.718 rs7859454 chr9:33119583 T/A cg20290983 chr6:43655470 MRPS18A 0.98 14.97 0.63 2.48e-39 IgG glycosylation; LIHC cis rs36051895 0.623 rs7847811 chr9:5237081 T/C cg02405213 chr9:5042618 JAK2 -0.66 -10.64 -0.5 5.12e-23 Pediatric autoimmune diseases; LIHC cis rs35110281 0.744 rs162398 chr21:44949285 T/C cg21573476 chr21:45109991 RRP1B -0.51 -9.32 -0.45 1.52e-18 Mean corpuscular volume; LIHC cis rs9513627 1.000 rs7317126 chr13:100119739 T/A cg25919922 chr13:100150906 NA -0.78 -7.02 -0.35 1.19e-11 Obesity-related traits; LIHC cis rs826838 1.000 rs1963562 chr12:38662896 C/T cg13010199 chr12:38710504 ALG10B 0.64 7.58 0.38 3.2e-13 Heart rate; LIHC cis rs10256972 0.967 rs7799110 chr7:1039065 A/G cg07308232 chr7:1071921 C7orf50 -0.48 -8.12 -0.4 8.47e-15 Longevity;Endometriosis; LIHC cis rs7116495 0.609 rs10736780 chr11:71650241 T/C cg26138937 chr11:71823887 C11orf51 -1.28 -10.0 -0.48 8.22e-21 Severe influenza A (H1N1) infection; LIHC cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg18306943 chr3:40428807 ENTPD3 -0.34 -5.93 -0.31 7.57e-9 Renal cell carcinoma; LIHC cis rs7116495 1.000 rs10751190 chr11:71680757 C/T cg26138937 chr11:71823887 C11orf51 -0.82 -8.17 -0.4 6.02e-15 Severe influenza A (H1N1) infection; LIHC cis rs4423214 1.000 rs11600569 chr11:71173747 C/G cg05163923 chr11:71159392 DHCR7 0.9 13.71 0.6 2.13e-34 Vitamin D levels; LIHC cis rs72480748 0.509 rs3865457 chr19:41398969 C/T cg14550611 chr19:41354682 CYP2A6 0.46 7.39 0.37 1.11e-12 Post bronchodilator FEV1;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); LIHC cis rs11148252 0.846 rs8001624 chr13:53002995 T/C cg00495681 chr13:53174319 NA 0.39 6.38 0.33 5.87e-10 Lewy body disease; LIHC cis rs7551222 0.752 rs4252677 chr1:204495253 G/A cg20240347 chr1:204465584 NA -0.36 -7.62 -0.38 2.58e-13 Schizophrenia; LIHC cis rs9733 0.680 rs3738484 chr1:150552330 G/T cg18016565 chr1:150552671 MCL1 -0.55 -11.08 -0.51 1.37e-24 Tonsillectomy; LIHC cis rs7312933 0.703 rs12370778 chr12:42599696 T/A cg01256987 chr12:42539512 GXYLT1 -0.41 -6.8 -0.34 4.77e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1843834 0.539 rs1494109 chr2:225441833 G/A cg22455342 chr2:225449267 CUL3 0.61 8.86 0.43 4.31e-17 IgE levels in asthmatics (D.p. specific); LIHC cis rs12893668 0.572 rs7148857 chr14:104143237 C/G cg24130564 chr14:104152367 KLC1 -0.55 -9.46 -0.46 5.27e-19 Reticulocyte count; LIHC cis rs9902453 0.817 rs2628170 chr17:28056612 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.73 -12.1 -0.55 2.74e-28 Coffee consumption (cups per day); LIHC cis rs2370759 1.000 rs16933225 chr10:32599464 C/T cg18270830 chr10:32634957 EPC1 0.57 7.13 0.36 6.03e-12 Sexual dysfunction (female); LIHC cis rs61677309 1.000 rs56318049 chr11:118166608 T/C cg06090739 chr11:118230722 UBE4A 0.35 6.58 0.34 1.82e-10 Lung cancer in ever smokers; LIHC cis rs8027181 1.000 rs4777542 chr15:73082366 C/T cg25632853 chr15:73088954 NA -0.39 -6.48 -0.33 3.15e-10 Triglyceride levels; LIHC cis rs9303401 0.659 rs34382037 chr17:56643550 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs8062405 0.755 rs7186573 chr16:28587389 T/C cg07451762 chr16:28383216 NA 0.4 7.18 0.36 4.29e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20285559 chr1:6688542 THAP3 -0.42 -6.28 -0.32 1.02e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7944735 0.564 rs60929305 chr11:47523589 C/T cg20307385 chr11:47447363 PSMC3 -0.54 -6.15 -0.32 2.18e-9 Intraocular pressure; LIHC cis rs2842992 0.872 rs2758330 chr6:160104844 G/T cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.07 0.55 3.42e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg18306943 chr3:40428807 ENTPD3 0.34 5.8 0.3 1.5e-8 Renal cell carcinoma; LIHC cis rs736801 0.521 rs2070729 chr5:131819921 G/T cg21138405 chr5:131827807 IRF1 0.26 6.54 0.33 2.23e-10 Breast cancer;Mosquito bite size; LIHC cis rs8027181 1.000 rs4776613 chr15:73080731 C/T cg25632853 chr15:73088954 NA 0.38 6.35 0.32 7.05e-10 Triglyceride levels; LIHC cis rs6748734 0.817 rs4465762 chr2:241798862 G/A cg09990169 chr2:241835740 C2orf54 -0.65 -10.48 -0.49 1.83e-22 Urinary metabolites; LIHC cis rs8067354 0.645 rs16943838 chr17:57839604 C/T cg13753209 chr17:57696993 CLTC 0.76 12.15 0.55 1.75e-28 Hemoglobin concentration; LIHC cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 7.97 0.4 2.39e-14 Schizophrenia; LIHC cis rs9393777 0.513 rs9393737 chr6:26617306 A/G cg12826209 chr6:26865740 GUSBL1 -0.57 -5.86 -0.3 1.11e-8 Intelligence (multi-trait analysis); LIHC cis rs6918586 0.616 rs1056314 chr6:26114653 G/A cg18357526 chr6:26021779 HIST1H4A 0.55 8.19 0.41 5.15e-15 Schizophrenia; LIHC cis rs6785206 0.527 rs9844706 chr3:128380781 G/A cg16766828 chr3:128327626 NA -0.56 -6.42 -0.33 4.54e-10 Lymphocyte percentage of white cells; LIHC cis rs9818758 0.556 rs9814987 chr3:49207849 T/C cg00383909 chr3:49044727 WDR6 0.89 7.55 0.38 4.12e-13 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2404602 0.735 rs4886800 chr15:76678692 A/G cg23625390 chr15:77176239 SCAPER -0.46 -7.55 -0.38 4.01e-13 Blood metabolite levels; LIHC cis rs1552244 0.882 rs13066757 chr3:10045030 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.04 -0.44 1.2e-17 Alzheimer's disease; LIHC cis rs12701220 0.655 rs12702117 chr7:1148702 T/C cg04025307 chr7:1156635 C7orf50 0.54 7.07 0.36 8.81e-12 Bronchopulmonary dysplasia; LIHC cis rs9457247 0.730 rs9459841 chr6:167431949 G/A cg23791538 chr6:167370224 RNASET2 -0.5 -7.74 -0.39 1.17e-13 Crohn's disease; LIHC cis rs2845885 0.793 rs35927325 chr11:63882495 C/T cg24431193 chr11:63883947 FLRT1;MACROD1 0.72 9.41 0.45 7.3e-19 Body mass index; LIHC cis rs7707921 0.881 rs73134722 chr5:81326622 G/A cg15871215 chr5:81402204 ATG10 -0.6 -5.77 -0.3 1.82e-8 Breast cancer; LIHC cis rs782590 0.935 rs10460508 chr2:55882565 A/C cg03859395 chr2:55845619 SMEK2 0.81 14.32 0.61 9.15e-37 Metabolic syndrome; LIHC cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg05368731 chr17:41323189 NBR1 0.73 12.63 0.56 2.82e-30 Menopause (age at onset); LIHC cis rs1568889 0.877 rs57202579 chr11:28221677 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.11 0.36 6.88e-12 Bipolar disorder; LIHC cis rs6076065 0.748 rs6048750 chr20:23334192 T/G cg11657817 chr20:23433608 CST11 0.31 6.66 0.34 1.1e-10 Facial morphology (factor 15, philtrum width); LIHC cis rs12142240 0.698 rs72890727 chr1:46860237 G/A cg14993813 chr1:46806288 NSUN4 -0.66 -5.97 -0.31 5.89e-9 Menopause (age at onset); LIHC cis rs3806843 1.000 rs2240692 chr5:140183585 A/G cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9318086 0.648 rs4067969 chr13:24469120 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.56 10.77 0.5 1.81e-23 Myopia (pathological); LIHC cis rs2836950 0.565 rs2836945 chr21:40596757 C/T cg11890956 chr21:40555474 PSMG1 -0.46 -7.43 -0.37 8.52e-13 Menarche (age at onset); LIHC cis rs8056893 0.714 rs3760002 chr16:68408836 A/G cg02226672 chr16:68398533 SMPD3 0.42 5.92 0.3 7.96e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13099106 chr12:120525172 CCDC64 0.41 6.39 0.33 5.42e-10 Cognitive function; LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg21782813 chr7:2030301 MAD1L1 0.5 8.72 0.43 1.25e-16 Bipolar disorder and schizophrenia; LIHC cis rs116248771 0.739 rs2291595 chr3:158378847 A/G cg16708174 chr3:158430962 RARRES1 0.48 6.38 0.33 5.61e-10 diarrhoeal disease at age 2; LIHC cis rs7927592 0.956 rs2155730 chr11:68329474 T/C cg20283391 chr11:68216788 NA -0.5 -7.51 -0.38 5.32e-13 Total body bone mineral density; LIHC cis rs2066819 1.000 rs77447765 chr12:56690662 G/A cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs477895 0.652 rs72920332 chr11:63947071 G/T cg04317338 chr11:64019027 PLCB3 0.85 10.21 0.48 1.51e-21 Mean platelet volume; LIHC cis rs12765878 0.967 rs11598018 chr10:105661315 C/A cg11005552 chr10:105648138 OBFC1 0.38 6.09 0.31 3.03e-9 Coronary artery disease; LIHC cis rs8180040 0.966 rs6765990 chr3:47542894 G/A cg27129171 chr3:47204927 SETD2 0.58 9.91 0.47 1.65e-20 Colorectal cancer; LIHC cis rs748404 0.697 rs564946 chr15:43556272 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.8 0.35 4.71e-11 Lung cancer; LIHC cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg11952622 chr19:58962976 ZNF324B 0.49 7.31 0.37 1.85e-12 Uric acid clearance; LIHC cis rs7903847 0.642 rs11817852 chr10:99158426 C/T cg08345082 chr10:99160200 RRP12 -0.4 -6.6 -0.34 1.6e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7937890 0.810 rs10734224 chr11:14424124 G/T cg02886208 chr11:14281011 SPON1 -0.52 -7.33 -0.37 1.7e-12 Mitochondrial DNA levels; LIHC trans rs4843747 0.605 rs28399183 chr16:88107277 G/A cg26811252 chr16:29126840 RRN3P2 0.42 6.8 0.35 4.59e-11 Menopause (age at onset); LIHC cis rs611744 0.967 rs637626 chr8:109235785 G/T cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg23283495 chr1:209979779 IRF6 0.45 7.47 0.37 6.81e-13 Cleft lip with or without cleft palate; LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg08280861 chr8:58055591 NA -0.49 -6.09 -0.31 3.04e-9 Developmental language disorder (linguistic errors); LIHC cis rs9309711 0.643 rs10188449 chr2:3480366 T/C cg15541040 chr2:3486749 NA -0.38 -6.07 -0.31 3.39e-9 Neurofibrillary tangles; LIHC cis rs7131987 0.903 rs10843367 chr12:29408380 G/A cg05697976 chr12:29376483 FAR2 0.31 6.13 0.31 2.44e-9 QT interval; LIHC cis rs7523273 0.568 rs11118668 chr1:208017915 A/G cg22525895 chr1:207977042 MIR29B2 0.6 6.9 0.35 2.47e-11 Schizophrenia; LIHC cis rs56104184 0.775 rs73061694 chr19:49399978 T/C cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs6762477 0.748 rs11711407 chr3:50225029 A/G cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.5 -7.17 -0.36 4.74e-12 Menarche (age at onset); LIHC cis rs9814567 0.806 rs11927539 chr3:134319448 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg17971929 chr21:40555470 PSMG1 -0.5 -7.62 -0.38 2.57e-13 Cognitive function; LIHC cis rs34375054 0.752 rs12582867 chr12:125659798 A/C cg25124228 chr12:125621409 AACS -0.42 -7.07 -0.36 8.89e-12 Post bronchodilator FEV1/FVC ratio; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg18844144 chr14:23528430 ACIN1 0.39 6.75 0.34 6.26e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs1757171 0.504 rs11969056 chr6:37484285 C/T cg08126542 chr6:37504118 NA -0.37 -6.25 -0.32 1.23e-9 Cognitive performance; LIHC cis rs11676348 1.000 rs11676348 chr2:219010146 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.42 -5.76 -0.3 1.84e-8 Ulcerative colitis; LIHC cis rs3824867 0.920 rs4282946 chr11:47456202 G/A cg20307385 chr11:47447363 PSMC3 0.59 8.12 0.4 8.73e-15 Mean corpuscular hemoglobin; LIHC cis rs798554 0.757 rs2533879 chr7:2859847 G/A cg04166393 chr7:2884313 GNA12 0.48 6.62 0.34 1.36e-10 Height; LIHC cis rs61990749 0.597 rs3783980 chr14:78219807 T/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.75 -0.39 1.02e-13 Fibroblast growth factor basic levels; LIHC cis rs6502050 0.871 rs62079994 chr17:80076516 T/C cg11859384 chr17:80120422 CCDC57 0.43 5.9 0.3 8.52e-9 Life satisfaction; LIHC cis rs2180341 0.782 rs6912750 chr6:127723081 A/T cg27446573 chr6:127587934 RNF146 0.79 13.15 0.58 3.06e-32 Breast cancer; LIHC cis rs921968 0.565 rs6761437 chr2:219598092 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.654 rs7482446 chr11:49779020 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.81 0.35 4.4e-11 Height; LIHC cis rs6695567 1.000 rs6672178 chr1:53629849 C/T cg20326410 chr1:53600821 SLC1A7 0.3 6.34 0.32 7.26e-10 Systemic lupus erythematosus; LIHC cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg16145915 chr7:1198662 ZFAND2A -0.38 -9.83 -0.47 3e-20 Longevity;Endometriosis; LIHC trans rs4843747 0.641 rs11117353 chr16:88090895 A/G cg09572067 chr16:29127029 RRN3P2 0.54 8.69 0.43 1.53e-16 Menopause (age at onset); LIHC cis rs2153535 0.580 rs9378554 chr6:8488468 C/T cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs4268898 0.722 rs7563958 chr2:24422381 C/A cg06627628 chr2:24431161 ITSN2 0.49 7.08 0.36 8.48e-12 Asthma; LIHC cis rs875971 0.755 rs76288834 chr7:66069802 G/A cg18876405 chr7:65276391 NA -0.33 -6.06 -0.31 3.62e-9 Aortic root size; LIHC trans rs2727020 0.729 rs6485965 chr11:49166730 C/T cg15704280 chr7:45808275 SEPT13 0.86 15.64 0.65 5.86e-42 Coronary artery disease; LIHC cis rs589448 0.967 rs2617834 chr12:69753365 T/C cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 1.02e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs1215050 0.791 rs1215055 chr4:98865454 C/T cg05340658 chr4:99064831 C4orf37 -0.39 -5.82 -0.3 1.34e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg10687131 chr2:20871002 GDF7 -0.36 -6.86 -0.35 3.16e-11 Abdominal aortic aneurysm; LIHC cis rs7129556 0.520 rs6592737 chr11:77322619 A/T cg03570279 chr11:77446074 RSF1 -0.36 -6.71 -0.34 8.27e-11 Weight loss (gastric bypass surgery); LIHC cis rs3780378 0.875 rs4372063 chr9:5003338 C/T cg02405213 chr9:5042618 JAK2 -0.44 -7.25 -0.37 2.73e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs9517302 0.615 rs2274053 chr13:99098318 C/T cg24044564 chr13:99115944 STK24 0.49 7.03 0.36 1.15e-11 Obesity-related traits; LIHC cis rs72627123 0.500 rs7359018 chr14:74521008 T/C cg05179529 chr14:74551516 LIN52;ALDH6A1 0.53 7.33 0.37 1.66e-12 Morning vs. evening chronotype; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.68 0.8 5.83e-78 Prudent dietary pattern; LIHC cis rs9457247 0.765 rs4710171 chr6:167430186 A/G cg23791538 chr6:167370224 RNASET2 -0.51 -7.79 -0.39 7.9e-14 Crohn's disease; LIHC cis rs7927771 0.800 rs55876153 chr11:47416636 G/A cg20135002 chr11:47629003 NA -0.54 -9.11 -0.44 7.33e-18 Subjective well-being; LIHC cis rs2108622 0.683 rs111388185 chr19:15977414 T/C cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg21298408 chr8:18027853 NAT1 -0.26 -6.18 -0.32 1.81e-9 Monocyte count; LIHC cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg02359409 chr6:42947317 PEX6 -0.41 -5.91 -0.3 8.38e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7615952 0.641 rs7618515 chr3:125790578 C/T cg05084668 chr3:125655381 ALG1L -0.39 -6.0 -0.31 5.11e-9 Blood pressure (smoking interaction); LIHC cis rs2050392 0.517 rs2489847 chr10:30743673 G/A cg25182066 chr10:30743637 MAP3K8 -0.72 -11.45 -0.53 6.44e-26 Inflammatory bowel disease; LIHC cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg02290350 chr8:58132656 NA 0.41 7.7 0.38 1.43e-13 Developmental language disorder (linguistic errors); LIHC trans rs78049276 0.688 rs17612693 chr4:148365339 T/A cg13149281 chr14:23389818 RBM23;PRMT5 -0.62 -7.69 -0.38 1.6e-13 Pulse pressure; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg11494091 chr17:61959527 GH2 0.44 8.14 0.4 7.19e-15 Prudent dietary pattern; LIHC trans rs1005277 0.579 rs176838 chr10:38371899 A/T cg17830980 chr10:43048298 ZNF37B 0.55 11.28 0.52 2.75e-25 Extrinsic epigenetic age acceleration; LIHC cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg17372223 chr3:52568218 NT5DC2 0.36 5.91 0.3 8.3e-9 Bipolar disorder; LIHC cis rs6665290 0.901 rs61834004 chr1:227202782 G/A cg10327440 chr1:227177885 CDC42BPA -1.15 -28.19 -0.84 3.3e-91 Myeloid white cell count; LIHC cis rs2540917 0.728 rs888082 chr2:60629609 C/T cg00543073 chr2:60773386 BCL11A -0.34 -6.67 -0.34 1.04e-10 Mean corpuscular volume; LIHC cis rs17376456 0.825 rs13171131 chr5:93223028 C/T cg25358565 chr5:93447407 FAM172A 1.05 9.76 0.47 5.19e-20 Diabetic retinopathy; LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg05484376 chr2:27715224 FNDC4 0.37 6.34 0.32 7.32e-10 Total body bone mineral density; LIHC cis rs1707322 0.686 rs2050376 chr1:46078630 C/T cg24296786 chr1:45957014 TESK2 -0.46 -6.59 -0.34 1.67e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9814567 1.000 rs13081688 chr3:134259954 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg05481257 chr2:20870211 GDF7 -0.43 -8.25 -0.41 3.42e-15 Abdominal aortic aneurysm; LIHC cis rs17685 0.753 rs4732595 chr7:75755139 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.51 -0.38 5.36e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2404602 0.692 rs7169663 chr15:77192843 A/C cg23625390 chr15:77176239 SCAPER 0.35 5.74 0.3 2.06e-8 Blood metabolite levels; LIHC cis rs9640161 0.830 rs17173682 chr7:150059602 A/G cg21361702 chr7:150065534 REPIN1 0.54 7.69 0.38 1.55e-13 Blood protein levels;Circulating chemerin levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23283076 chr1:27114325 PIGV -0.52 -6.14 -0.32 2.34e-9 Systolic blood pressure; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg06420487 chr17:61919686 SMARCD2 0.42 5.78 0.3 1.69e-8 Height; LIHC cis rs7635838 0.684 rs2606762 chr3:11343889 G/C cg00170343 chr3:11313890 ATG7 0.6 10.25 0.48 1.16e-21 HDL cholesterol; LIHC cis rs35883536 0.626 rs10783140 chr1:101042083 A/G cg14515779 chr1:101123966 NA 0.46 6.6 0.34 1.61e-10 Monocyte count; LIHC cis rs876084 0.505 rs12680859 chr8:121118968 A/G cg06265175 chr8:121136014 COL14A1 0.42 6.91 0.35 2.38e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs919433 0.927 rs1429418 chr2:198158151 G/C cg03934865 chr2:198174659 NA -0.59 -9.44 -0.45 5.84e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9303401 0.659 rs62083525 chr17:56658088 A/G cg25039879 chr17:56429692 SUPT4H1 0.79 8.97 0.44 1.98e-17 Cognitive test performance; LIHC cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg18306943 chr3:40428807 ENTPD3 0.35 6.09 0.31 3.1e-9 Renal cell carcinoma; LIHC cis rs6787391 0.933 rs12330193 chr3:4748862 C/T cg11584376 chr3:4789075 ITPR1 -0.38 -5.84 -0.3 1.2e-8 Breast cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23131702 chr10:5726677 C10orf18 0.44 6.22 0.32 1.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4728302 0.838 rs10225115 chr7:133591435 C/T cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg10360139 chr7:1886902 MAD1L1 -0.38 -5.88 -0.3 9.71e-9 Bipolar disorder and schizophrenia; LIHC cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg23205692 chr1:25664452 TMEM50A 0.39 6.29 0.32 9.64e-10 Erythrocyte sedimentation rate; LIHC cis rs250677 0.687 rs168750 chr5:148446756 A/G cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC cis rs7551222 0.646 rs4951384 chr1:204452514 A/T cg20240347 chr1:204465584 NA -0.31 -6.55 -0.33 2.09e-10 Schizophrenia; LIHC cis rs904251 0.737 rs914347 chr6:37484970 A/C cg25019722 chr6:37503610 NA -0.37 -6.38 -0.33 5.8e-10 Cognitive performance; LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg23131131 chr22:24373011 LOC391322 0.61 8.77 0.43 8.39e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2576037 0.583 rs501882 chr18:44411066 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 9.76 0.47 5.23e-20 Personality dimensions; LIHC cis rs4722166 0.630 rs7808457 chr7:22798265 A/T cg05472934 chr7:22766657 IL6 -0.51 -7.35 -0.37 1.48e-12 Lung cancer; LIHC cis rs7618501 0.699 rs11130224 chr3:49936910 T/A cg24110177 chr3:50126178 RBM5 -0.5 -7.78 -0.39 8.56e-14 Intelligence (multi-trait analysis); LIHC cis rs787274 0.867 rs787269 chr9:115548676 T/C cg13803584 chr9:115635662 SNX30 -0.58 -6.32 -0.32 8.19e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs651907 0.557 rs11924013 chr3:101366698 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.69 11.69 0.53 8.43e-27 Colorectal cancer; LIHC cis rs12079745 0.793 rs78483993 chr1:169410428 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.72 -6.62 -0.34 1.37e-10 QT interval; LIHC cis rs10905065 0.861 rs10752069 chr10:5752403 A/G cg11519256 chr10:5708881 ASB13 0.46 6.06 0.31 3.54e-9 Menopause (age at onset); LIHC cis rs3820068 0.581 rs72645864 chr1:15921153 C/T cg17385448 chr1:15911702 AGMAT 0.34 5.88 0.3 9.56e-9 Systolic blood pressure; LIHC cis rs694739 1.000 rs11231757 chr11:64106317 C/T cg02228329 chr11:64053129 BAD;GPR137 0.72 10.28 0.49 8.94e-22 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs17106184 1.000 rs72904719 chr1:51324546 G/T cg07174182 chr1:51127561 FAF1 -0.62 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC cis rs1707322 1.000 rs34444543 chr1:46358862 G/A cg03146154 chr1:46216737 IPP 0.48 7.71 0.38 1.42e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3741404 0.620 rs2236647 chr11:63964605 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.69 -10.44 -0.49 2.52e-22 Platelet count; LIHC cis rs2243480 0.522 rs778717 chr7:65848151 G/C cg12463550 chr7:65579703 CRCP 0.7 6.74 0.34 6.84e-11 Diabetic kidney disease; LIHC cis rs12458462 0.892 rs2242174 chr18:77458037 T/C cg11879182 chr18:77439856 CTDP1 0.84 14.35 0.61 7.23e-37 Monocyte count; LIHC cis rs6930083 0.527 rs9368950 chr6:36627872 T/C cg08179530 chr6:36648295 CDKN1A -0.66 -9.79 -0.47 4.12e-20 Coronary artery disease; LIHC cis rs614226 0.938 rs787824 chr12:120924638 A/G cg01236616 chr12:121019343 POP5 -0.93 -14.71 -0.62 2.61e-38 Type 1 diabetes nephropathy; LIHC cis rs35362007 0.530 rs10484053 chr14:96011645 C/T cg13511115 chr14:96000878 GLRX5;SNHG10;SCARNA13 0.79 6.64 0.34 1.22e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7940866 0.874 rs7112616 chr11:130805334 T/C cg12179176 chr11:130786555 SNX19 0.61 8.84 0.43 5.17e-17 Schizophrenia; LIHC trans rs116095464 0.614 rs62344292 chr5:244630 G/A cg00938859 chr5:1591904 SDHAP3 0.57 7.0 0.35 1.36e-11 Breast cancer; LIHC cis rs812925 0.537 rs778139 chr2:61684564 A/G cg14146966 chr2:61757674 XPO1 -0.39 -6.55 -0.33 2.1e-10 Immature fraction of reticulocytes; LIHC cis rs55823223 0.564 rs58363746 chr17:73850819 C/T cg14829360 chr17:73884958 NA -0.49 -7.25 -0.36 2.84e-12 Psoriasis; LIHC trans rs4714291 0.802 rs2983140 chr6:40017224 A/G cg02267698 chr19:7991119 CTXN1 -0.42 -7.02 -0.35 1.18e-11 Strep throat; LIHC cis rs7909074 1.000 rs1408814 chr10:45399088 A/G cg05187965 chr10:45406764 TMEM72 -0.27 -6.76 -0.34 5.97e-11 Mean corpuscular volume; LIHC cis rs2153535 0.580 rs2143354 chr6:8517907 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs2153535 0.562 rs10458225 chr6:8386004 G/A cg07606381 chr6:8435919 SLC35B3 -0.75 -11.73 -0.54 6.36e-27 Motion sickness; LIHC cis rs9911578 1.000 rs1971659 chr17:57004787 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.659 rs56162835 chr17:56687315 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs2425143 1.000 rs8116836 chr20:34453362 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.55 -7.4 -0.37 1.04e-12 Blood protein levels; LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg07308232 chr7:1071921 C7orf50 -0.38 -6.12 -0.31 2.61e-9 Longevity;Endometriosis; LIHC cis rs7927592 0.763 rs7119422 chr11:68331154 C/T cg16797656 chr11:68205561 LRP5 -0.5 -8.88 -0.43 3.86e-17 Total body bone mineral density; LIHC cis rs3020736 0.500 rs6002597 chr22:42488160 C/A cg05082376 chr22:42548792 NA 0.39 5.71 0.3 2.41e-8 Autism spectrum disorder or schizophrenia; LIHC trans rs6058796 0.892 rs34894833 chr20:31247154 G/A cg02600331 chr11:130417168 NA 0.32 6.92 0.35 2.17e-11 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs227584 0.501 rs62078931 chr17:42198059 A/C cg09913183 chr17:42254507 C17orf65;ASB16 -0.61 -9.06 -0.44 1.02e-17 Bone mineral density (hip);Bone mineral density; LIHC trans rs2727020 0.729 rs2866328 chr11:49282421 A/G cg03929089 chr4:120376271 NA 0.81 14.19 0.61 2.86e-36 Coronary artery disease; LIHC cis rs9486715 1.000 rs9386670 chr6:97060688 C/A cg06623918 chr6:96969491 KIAA0776 -0.79 -12.07 -0.55 3.48e-28 Headache; LIHC cis rs1008375 1.000 rs11737138 chr4:17657986 G/A cg02297831 chr4:17616191 MED28 0.5 7.83 0.39 6.02e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC cis rs12893668 0.703 rs4906337 chr14:104040414 C/A cg19000871 chr14:103996768 TRMT61A -0.44 -7.16 -0.36 5.12e-12 Reticulocyte count; LIHC cis rs5769765 0.862 rs9616774 chr22:50290599 G/A cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.25e-16 Schizophrenia; LIHC cis rs4803468 1.000 rs2288871 chr19:41917868 C/T cg09537434 chr19:41945824 ATP5SL -1.02 -21.53 -0.76 1.31e-65 Height; LIHC cis rs12579753 0.879 rs10778828 chr12:82117216 C/A cg07988820 chr12:82153109 PPFIA2 -0.5 -6.2 -0.32 1.58e-9 Resting heart rate; LIHC cis rs6500602 0.727 rs12443748 chr16:4541831 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.73 0.3 2.22e-8 Schizophrenia; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg24209194 chr3:40518798 ZNF619 0.55 8.02 0.4 1.69e-14 Renal cell carcinoma; LIHC cis rs10744422 1.000 rs10847869 chr12:123328359 C/G cg22842854 chr12:123319900 HIP1R -0.65 -8.57 -0.42 3.5e-16 Schizophrenia; LIHC cis rs3806843 0.735 rs801167 chr5:140081423 A/G cg26395211 chr5:140044315 WDR55 -0.41 -5.89 -0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs72829446 0.530 rs9891297 chr17:7385204 T/C cg08566640 chr11:64091735 NA -0.67 -6.13 -0.31 2.36e-9 Androgen levels; LIHC trans rs2832191 0.632 rs2246777 chr21:30309586 T/C cg14791747 chr16:20752902 THUMPD1 0.46 6.24 0.32 1.28e-9 Dental caries; LIHC cis rs7512552 0.839 rs1103115 chr1:150332304 G/A cg15654264 chr1:150340011 RPRD2 0.69 11.33 0.52 1.78e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs3617 0.573 rs6795646 chr3:52922621 C/T cg11645453 chr3:52864694 ITIH4 -0.22 -5.97 -0.31 6.07e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs4555082 0.750 rs2816650 chr14:105708343 C/T cg13114125 chr14:105738426 BRF1 -0.78 -10.15 -0.48 2.53e-21 Mean platelet volume;Platelet distribution width; LIHC trans rs9836270 1.000 rs9836270 chr3:131916996 G/T cg13445339 chr1:11721249 FBXO44 -0.36 -6.18 -0.32 1.81e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs58688157 0.705 rs7928902 chr11:609068 G/A cg16486109 chr11:613632 IRF7 0.58 6.22 0.32 1.48e-9 Systemic lupus erythematosus; LIHC cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg09455208 chr3:40491958 NA -0.34 -6.74 -0.34 6.79e-11 Renal cell carcinoma; LIHC cis rs74181299 0.892 rs2249105 chr2:65287896 C/T cg05010058 chr2:65284262 CEP68 -0.4 -6.78 -0.34 5.35e-11 Pulse pressure; LIHC cis rs1475911 0.656 rs9980065 chr21:43528072 G/A cg24372256 chr21:43528868 UMODL1;C21orf128 -0.42 -6.13 -0.31 2.44e-9 IgG glycosylation; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg09453983 chr4:146080425 OTUD4 -0.24 -6.15 -0.32 2.11e-9 Calcium levels; LIHC cis rs3820068 0.532 rs74057713 chr1:15944620 G/C cg17385448 chr1:15911702 AGMAT 0.37 6.44 0.33 4.09e-10 Systolic blood pressure; LIHC cis rs6456156 0.528 rs6936261 chr6:167469676 A/C cg12798992 chr6:167411361 FGFR1OP 0.51 8.33 0.41 1.97e-15 Primary biliary cholangitis; LIHC cis rs734999 0.545 rs4474198 chr1:2553758 C/T cg18854424 chr1:2615690 NA 0.36 8.19 0.4 5.25e-15 Ulcerative colitis; LIHC trans rs2073499 1.000 rs3806708 chr3:50306249 T/C cg21659725 chr3:3221576 CRBN 0.62 6.76 0.34 5.97e-11 Schizophrenia; LIHC trans rs9951602 0.512 rs56009939 chr18:76644497 T/G cg02800362 chr5:177631904 HNRNPAB 0.64 10.24 0.48 1.24e-21 Obesity-related traits; LIHC trans rs7618501 0.521 rs6774354 chr3:49961780 G/A cg21659725 chr3:3221576 CRBN 0.56 8.27 0.41 2.93e-15 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.731 rs2322660 chr2:136557319 A/G cg17750252 chr2:136567154 LCT -0.35 -6.33 -0.32 7.54e-10 Mosquito bite size; LIHC cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg00612595 chr21:47717864 NA -0.35 -5.71 -0.3 2.45e-8 Testicular germ cell tumor; LIHC cis rs2836950 0.565 rs2836934 chr21:40564885 A/C cg06238570 chr21:40685208 BRWD1 -0.41 -6.64 -0.34 1.21e-10 Menarche (age at onset); LIHC cis rs4853012 0.941 rs60291089 chr2:74344890 T/G cg05890377 chr2:74357713 NA 0.63 12.68 0.57 1.89e-30 Gestational age at birth (maternal effect); LIHC cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg18225595 chr11:63971243 STIP1 0.66 8.28 0.41 2.87e-15 Mean platelet volume; LIHC cis rs7618501 0.633 rs4688689 chr3:50035542 C/T cg21467203 chr3:49911342 NA -0.43 -7.71 -0.38 1.38e-13 Intelligence (multi-trait analysis); LIHC trans rs561341 0.883 rs1034627 chr17:30219569 C/T cg20587970 chr11:113659929 NA -0.65 -7.96 -0.4 2.53e-14 Hip circumference adjusted for BMI; LIHC cis rs2295359 0.824 rs4655679 chr1:67599657 A/G cg12940439 chr1:67600707 NA -0.35 -6.32 -0.32 8e-10 Psoriasis; LIHC cis rs2073300 0.609 rs6137937 chr20:23385419 G/A cg12062639 chr20:23401060 NAPB 1.07 14.15 0.61 4.34e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3806843 1.000 rs2879089 chr5:140191893 A/T cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9910055 0.529 rs408282 chr17:42182267 A/G cg19774624 chr17:42201019 HDAC5 0.48 5.78 0.3 1.64e-8 Total body bone mineral density; LIHC cis rs17685 0.753 rs1637051 chr7:75730659 G/A cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.76e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1580019 0.539 rs11769109 chr7:32571352 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.12 25.1 0.81 1.47e-79 Cognitive ability; LIHC cis rs758324 0.947 rs10054618 chr5:131195002 C/T cg06307176 chr5:131281290 NA 0.4 5.71 0.3 2.45e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs6061231 0.837 rs6061235 chr20:60978524 C/G cg22601191 chr20:60968625 CABLES2 0.45 5.81 0.3 1.4e-8 Colorectal cancer; LIHC cis rs11676348 0.818 rs1126579 chr2:219000734 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.13 -0.31 2.37e-9 Ulcerative colitis; LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs6714710 0.580 rs55886305 chr2:98495661 T/G cg26665480 chr2:98280029 ACTR1B 0.44 6.2 0.32 1.67e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs9457247 0.765 rs1060404 chr6:167429467 A/G cg07741184 chr6:167504864 NA 0.32 7.36 0.37 1.42e-12 Crohn's disease; LIHC cis rs4908768 0.906 rs12410336 chr1:8623664 A/G cg20416874 chr1:8611966 RERE 0.57 8.75 0.43 1.02e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg09367891 chr1:107599246 PRMT6 -0.72 -11.91 -0.54 1.32e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7258465 1.000 rs2303697 chr19:18546678 T/C cg10790698 chr19:18539756 SSBP4 -0.36 -7.26 -0.37 2.63e-12 Breast cancer; LIHC cis rs8114671 0.562 rs1018447 chr20:33401707 A/G cg07148914 chr20:33460835 GGT7 -0.58 -8.74 -0.43 1.08e-16 Height; LIHC cis rs910316 0.967 rs175505 chr14:75529619 C/T cg11812906 chr14:75593930 NEK9 -0.77 -15.12 -0.63 6.75e-40 Height; LIHC trans rs61931739 0.500 rs3924704 chr12:34557833 C/T cg26384229 chr12:38710491 ALG10B 0.79 9.54 0.46 2.8e-19 Morning vs. evening chronotype; LIHC cis rs6138458 1.000 rs227627 chr20:24912107 T/C cg26195577 chr20:24973756 C20orf3 1.13 14.83 0.63 9.14e-39 Blood protein levels; LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg10360139 chr7:1886902 MAD1L1 -0.4 -6.05 -0.31 3.89e-9 Bipolar disorder and schizophrenia; LIHC cis rs1185460 0.967 rs1786684 chr11:118938435 G/A cg23280166 chr11:118938394 VPS11 0.61 8.35 0.41 1.75e-15 Coronary artery disease; LIHC cis rs8072100 0.576 rs7216112 chr17:45406345 C/T cg25173405 chr17:45401733 C17orf57 0.55 7.46 0.37 6.99e-13 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18210722 chr7:74379144 GATSL1 -0.49 -6.07 -0.31 3.4e-9 Lung function (FEV1/FVC); LIHC cis rs7618501 1.000 rs3749240 chr3:49750188 T/A cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC cis rs9399135 0.967 rs4376365 chr6:135307740 T/C cg24558204 chr6:135376177 HBS1L 0.4 6.58 0.34 1.79e-10 Red blood cell count; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13231117 chr2:96193797 NA 0.5 7.04 0.36 1.07e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7412746 0.658 rs6656535 chr1:150940357 G/T cg15448220 chr1:150897856 SETDB1 0.43 6.83 0.35 3.86e-11 Melanoma; LIHC cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg11663144 chr21:46675770 NA -0.34 -6.32 -0.32 7.99e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7614311 0.731 rs3733121 chr3:63850660 C/G cg22134162 chr3:63841271 THOC7 -0.56 -6.38 -0.33 5.68e-10 Lung function (FVC);Lung function (FEV1); LIHC cis rs1008375 1.000 rs6811887 chr4:17640858 C/T cg16339924 chr4:17578868 LAP3 0.44 6.08 0.31 3.19e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13745513 chr9:131018379 GOLGA2 0.45 6.2 0.32 1.6e-9 Hepatitis; LIHC cis rs7223966 1.000 rs11658329 chr17:61763031 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.58 -6.91 -0.35 2.35e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs875971 1.000 rs2036264 chr7:65799904 G/A cg18252515 chr7:66147081 NA 0.42 5.88 0.3 9.6e-9 Aortic root size; LIHC cis rs2742417 0.603 rs7631818 chr3:45775931 A/T cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs7845219 0.544 rs10956930 chr8:95919786 C/G cg13393036 chr8:95962371 TP53INP1 -0.31 -5.89 -0.3 9.33e-9 Type 2 diabetes; LIHC cis rs637571 0.522 rs542332 chr11:65744421 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.28 0.45 1.98e-18 Eosinophil percentage of white cells; LIHC trans rs916888 0.773 rs199534 chr17:44824213 T/G cg26692224 chr17:62915920 LRRC37A3 -0.73 -7.05 -0.36 1.01e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4665809 0.878 rs892448 chr2:26366205 A/G cg27170947 chr2:26402098 FAM59B -0.67 -8.43 -0.41 9.64e-16 Gut microbiome composition (summer); LIHC cis rs2153535 0.601 rs969420 chr6:8451966 T/A cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC trans rs11148252 1.000 rs11148252 chr13:53009048 C/T cg18335740 chr13:41363409 SLC25A15 0.35 6.15 0.32 2.19e-9 Lewy body disease; LIHC cis rs743757 0.878 rs6786523 chr3:50524221 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.41 -6.11 -0.31 2.66e-9 Diastolic blood pressure; LIHC cis rs7568458 0.783 rs1561198 chr2:85809989 C/T cg02493740 chr2:85810744 VAMP5 -0.33 -5.77 -0.3 1.76e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2933343 0.621 rs4927921 chr3:128568868 A/G cg25356066 chr3:128598488 ACAD9 -0.48 -6.79 -0.34 5.05e-11 IgG glycosylation; LIHC cis rs2228479 0.850 rs62054599 chr16:89808850 C/G cg06558623 chr16:89946397 TCF25 0.87 11.95 0.54 9.72e-28 Skin colour saturation; LIHC cis rs6430585 0.527 rs57530667 chr2:136444338 A/G cg07169764 chr2:136633963 MCM6 0.67 8.59 0.42 3.21e-16 Corneal structure; LIHC cis rs2292864 0.764 rs72825627 chr17:45386289 C/G cg18085866 chr17:45331354 ITGB3 -0.6 -6.26 -0.32 1.12e-9 Left atrial antero-posterior diameter; LIHC cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg06873352 chr17:61820015 STRADA 0.5 7.44 0.37 8.28e-13 Height; LIHC cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg04025307 chr7:1156635 C7orf50 0.55 9.11 0.44 6.99e-18 Longevity;Endometriosis; LIHC trans rs1005277 0.579 rs932538 chr10:38381314 T/C cg17830980 chr10:43048298 ZNF37B -0.53 -10.74 -0.5 2.25e-23 Extrinsic epigenetic age acceleration; LIHC cis rs8044868 0.586 rs6499564 chr16:72189655 G/A cg16558253 chr16:72132732 DHX38 -0.41 -6.82 -0.35 4.06e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs9368481 0.547 rs2093303 chr6:26864406 C/T cg12292205 chr6:26970375 C6orf41 0.41 6.93 0.35 2.07e-11 Autism spectrum disorder or schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06154860 chr7:14029085 ETV1 0.46 7.07 0.36 8.71e-12 Cognitive function; LIHC trans rs6489882 0.867 rs4766673 chr12:113365161 C/T cg10175203 chr3:128143634 NA -0.39 -6.4 -0.33 5.11e-10 Chronic lymphocytic leukemia; LIHC cis rs7615952 0.688 rs9754526 chr3:125542866 C/A cg05084668 chr3:125655381 ALG1L -0.34 -6.1 -0.31 2.87e-9 Blood pressure (smoking interaction); LIHC cis rs798554 0.610 rs2644304 chr7:2878779 T/C cg13628971 chr7:2884303 GNA12 0.37 5.75 0.3 2.01e-8 Height; LIHC cis rs9549367 0.756 rs3861723 chr13:113910926 A/G cg00898013 chr13:113819073 PROZ -0.34 -6.13 -0.31 2.39e-9 Platelet distribution width; LIHC cis rs933688 1.000 rs1964292 chr5:90743608 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.35 0.72 6.94e-57 Smoking behavior; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01538984 chr7:140396422 LOC100134713;NDUFB2 0.42 6.75 0.34 6.41e-11 Cognitive function; LIHC cis rs7258465 1.000 rs8111708 chr19:18558876 A/G cg10790698 chr19:18539756 SSBP4 -0.37 -7.7 -0.38 1.52e-13 Breast cancer; LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg09455208 chr3:40491958 NA -0.41 -8.44 -0.42 9e-16 Renal cell carcinoma; LIHC cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg14983838 chr19:29218262 NA 0.49 7.27 0.37 2.44e-12 Methadone dose in opioid dependence; LIHC cis rs9419702 0.526 rs9419637 chr10:133548059 T/C cg04492858 chr10:133558786 NA 0.45 6.67 0.34 1.01e-10 Survival in rectal cancer; LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg08677398 chr8:58056175 NA 0.41 6.35 0.32 6.79e-10 Developmental language disorder (linguistic errors); LIHC cis rs6062302 0.540 rs2281926 chr20:62384309 G/C cg14758556 chr20:62440591 NA 0.42 6.63 0.34 1.33e-10 Glioblastoma; LIHC cis rs6088580 0.634 rs6059829 chr20:33017074 G/A cg08999081 chr20:33150536 PIGU 0.67 13.26 0.58 1.15e-32 Glomerular filtration rate (creatinine); LIHC cis rs1577917 0.876 rs1582127 chr6:86697204 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.25 -0.32 1.24e-9 Response to antipsychotic treatment; LIHC cis rs6088590 1.000 rs10048849 chr20:33419680 C/T cg06115741 chr20:33292138 TP53INP2 0.59 8.15 0.4 6.99e-15 Coronary artery disease; LIHC cis rs9896933 0.779 rs2256316 chr17:80693805 C/G cg20578329 chr17:80767326 TBCD -0.69 -6.93 -0.35 2.06e-11 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC trans rs4604234 0.803 rs79048064 chr6:80977098 G/T cg08069338 chr6:160207898 SNORA29;TCP1 0.63 6.16 0.32 2.07e-9 Cancer; LIHC cis rs611744 0.608 rs612744 chr8:109245991 G/A cg21045802 chr8:109455806 TTC35 0.59 10.3 0.49 7.86e-22 Dupuytren's disease; LIHC cis rs67311347 1.000 rs897117 chr3:40437294 C/T cg13409248 chr3:40428643 ENTPD3 -0.39 -6.25 -0.32 1.22e-9 Renal cell carcinoma; LIHC cis rs2288912 0.620 rs875255 chr19:45493635 C/G cg13119609 chr19:45449297 APOC2 -0.21 -6.08 -0.31 3.17e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03043160 chr13:76056444 TBC1D4 -0.49 -6.52 -0.33 2.6e-10 Lung function (FEV1/FVC); LIHC cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg03452623 chr4:187889614 NA -0.32 -8.36 -0.41 1.55e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618501 1.000 rs6802890 chr3:49832261 A/G cg21467203 chr3:49911342 NA -0.41 -7.03 -0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs35883536 0.647 rs12026951 chr1:101046273 C/T cg14515779 chr1:101123966 NA 0.52 7.42 0.37 9.23e-13 Monocyte count; LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs588193 chr17:37440439 A/C cg03013999 chr17:37608204 MED1 -0.36 -6.06 -0.31 3.53e-9 Glomerular filtration rate (creatinine); LIHC cis rs595982 0.559 rs73061632 chr19:49361663 G/A cg21252483 chr19:49399788 TULP2 -0.88 -9.9 -0.47 1.78e-20 Red cell distribution width; LIHC cis rs10870270 0.956 rs10781555 chr10:133745720 G/A cg17892150 chr10:133769511 PPP2R2D -0.7 -13.06 -0.58 6.64e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2645694 0.626 rs2703118 chr4:77823672 A/G cg06046430 chr4:77819534 ANKRD56 0.5 6.63 0.34 1.32e-10 Emphysema distribution in smoking; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.99 -0.4 2.14e-14 Lymphocyte counts; LIHC cis rs55823223 0.564 rs1463485 chr17:73851791 C/G cg14829360 chr17:73884958 NA -0.52 -7.79 -0.39 8.23e-14 Psoriasis; LIHC cis rs9916302 0.904 rs2338800 chr17:37498149 C/G cg00129232 chr17:37814104 STARD3 0.39 6.15 0.32 2.16e-9 Glomerular filtration rate (creatinine); LIHC trans rs1814175 0.935 rs7482690 chr11:49648814 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -21.57 -0.76 9e-66 Height; LIHC cis rs17106184 1.000 rs113910111 chr1:51328773 T/C cg07174182 chr1:51127561 FAF1 -0.62 -6.59 -0.34 1.68e-10 Type 2 diabetes; LIHC cis rs2191566 0.960 rs11083732 chr19:44520743 T/C cg18700516 chr19:44507157 ZNF230 -0.35 -5.86 -0.3 1.11e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs6750047 0.647 rs11124632 chr2:38276412 G/C cg07380506 chr2:38303506 CYP1B1 0.59 7.56 0.38 3.66e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs1494950 1.000 rs1494950 chr4:14967169 A/G cg12377275 chr4:15005593 CPEB2 -0.79 -6.7 -0.34 8.77e-11 Political ideology; LIHC cis rs2354432 0.599 rs6693667 chr1:146817245 A/T cg25205988 chr1:146714368 CHD1L 0.92 12.6 0.56 3.81e-30 Mitochondrial DNA levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg02674305 chr20:34359915 PHF20 0.42 6.05 0.31 3.73e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg13395646 chr4:1353034 KIAA1530 -0.66 -9.55 -0.46 2.64e-19 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19504496 chr19:36119917 RBM42 0.47 6.57 0.33 1.85e-10 Pancreatic cancer; LIHC cis rs4927850 1.000 rs6799572 chr3:195740408 C/T cg01181863 chr3:195395398 SDHAP2 -0.57 -7.37 -0.37 1.33e-12 Pancreatic cancer; LIHC cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg24209194 chr3:40518798 ZNF619 -0.43 -6.06 -0.31 3.55e-9 Renal cell carcinoma; LIHC trans rs2579103 0.767 rs1595601 chr12:90661368 T/C cg00091569 chr3:40428383 ENTPD3 0.37 6.12 0.31 2.5e-9 Body mass index; LIHC trans rs2270927 0.510 rs1995381 chr5:75570658 C/T cg13563193 chr19:33072644 PDCD5 -0.88 -9.19 -0.45 3.91e-18 Mean corpuscular volume; LIHC cis rs12079745 0.793 rs12071224 chr1:169191945 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -7.15 -0.36 5.34e-12 QT interval; LIHC trans rs13325613 0.915 rs71327041 chr3:46267582 C/T cg26337592 chr1:153642686 ILF2 0.68 6.18 0.32 1.81e-9 Monocyte count; LIHC cis rs752010 0.806 rs4641303 chr1:42091310 A/G cg06885757 chr1:42089581 HIVEP3 0.28 5.77 0.3 1.82e-8 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg06481639 chr22:41940642 POLR3H 0.67 6.76 0.34 5.87e-11 Vitiligo; LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg04234412 chr22:24373322 LOC391322 -0.7 -10.13 -0.48 2.89e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg04267008 chr7:1944627 MAD1L1 -0.67 -11.26 -0.52 3.2e-25 Bipolar disorder and schizophrenia; LIHC cis rs11098499 0.954 rs13113483 chr4:120309039 C/T cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs17106184 1.000 rs80297338 chr1:51255677 C/A cg07174182 chr1:51127561 FAF1 -0.64 -6.89 -0.35 2.74e-11 Type 2 diabetes; LIHC cis rs62244186 0.715 rs10212378 chr3:44667286 C/G cg25364880 chr3:44379878 C3orf23 0.56 7.62 0.38 2.53e-13 Depressive symptoms; LIHC cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg05564831 chr3:52568323 NT5DC2 0.37 6.08 0.31 3.28e-9 Electroencephalogram traits; LIHC cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg05368731 chr17:41323189 NBR1 0.72 12.12 0.55 2.21e-28 Menopause (age at onset); LIHC cis rs10504229 0.681 rs11779172 chr8:58045538 A/G cg02290350 chr8:58132656 NA 0.32 7.17 0.36 4.73e-12 Developmental language disorder (linguistic errors); LIHC cis rs9614461 0.702 rs16993867 chr22:45733199 A/G cg04014059 chr22:45813624 RIBC2 -0.46 -6.02 -0.31 4.37e-9 Tonsillectomy; LIHC cis rs2380220 0.808 rs2613547 chr6:95910311 C/T cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs1712517 0.835 rs2506961 chr10:105007926 G/T cg05636881 chr10:105038444 INA -0.43 -6.98 -0.35 1.53e-11 Migraine; LIHC cis rs2075165 0.901 rs759329 chr1:156230936 A/G cg20302342 chr1:156215951 PAQR6 0.35 6.65 0.34 1.14e-10 Tonsillectomy; LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg18306943 chr3:40428807 ENTPD3 0.43 7.51 0.38 5.31e-13 Renal cell carcinoma; LIHC cis rs17608059 0.545 rs9915045 chr17:13902636 G/T cg11395062 chr17:14139857 CDRT15 0.52 9.27 0.45 2.11e-18 Temperament; LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.6 9.26 0.45 2.38e-18 Height; LIHC cis rs7903847 0.642 rs2275089 chr10:99141205 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7020830 0.867 rs1339553 chr9:37266123 C/G cg14294708 chr9:37120828 ZCCHC7 1.12 23.57 0.79 1.24e-73 Schizophrenia; LIHC cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg26939375 chr7:64535504 NA 0.47 7.05 0.36 9.74e-12 Aortic root size; LIHC cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg23172400 chr8:95962367 TP53INP1 -0.36 -8.03 -0.4 1.61e-14 Type 2 diabetes; LIHC cis rs9733 0.744 rs2039590 chr1:150813315 G/A cg18016565 chr1:150552671 MCL1 -0.49 -9.6 -0.46 1.74e-19 Tonsillectomy; LIHC cis rs9328573 1.000 rs9328573 chr15:100511004 A/G cg09918751 chr15:100517450 ADAMTS17 -0.49 -7.42 -0.37 9.54e-13 Urate levels in lean individuals; LIHC cis rs2075371 1.000 rs2598285 chr7:133971153 A/T cg11752832 chr7:134001865 SLC35B4 0.5 7.57 0.38 3.52e-13 Mean platelet volume; LIHC cis rs427394 0.659 rs274675 chr5:6755319 C/T cg10857441 chr5:6722123 POLS -0.4 -6.67 -0.34 1.03e-10 Menopause (age at onset); LIHC cis rs67311347 1.000 rs2168111 chr3:40395325 T/G cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.46e-9 Renal cell carcinoma; LIHC cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg16049864 chr8:95962084 TP53INP1 -0.63 -11.77 -0.54 4.39e-27 Type 2 diabetes; LIHC cis rs2000999 0.691 rs11648003 chr16:72052348 A/G cg01557791 chr16:72042693 DHODH -0.67 -9.17 -0.44 4.68e-18 Total cholesterol levels;Cholesterol, total;Blood protein levels;LDL cholesterol levels;Haptoglobin levels;LDL cholesterol; LIHC cis rs3806843 0.735 rs2563335 chr5:140044292 A/C cg19875535 chr5:140030758 IK 0.42 6.74 0.34 6.75e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs77106637 0.860 rs11603334 chr11:72432985 G/A cg03878208 chr11:72483293 STARD10 0.63 5.76 0.3 1.83e-8 Type 2 diabetes; LIHC cis rs7927771 1.000 rs35902101 chr11:47795169 C/T cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.39e-18 Subjective well-being; LIHC cis rs116095464 0.558 rs114607464 chr5:300468 C/T cg22496380 chr5:211416 CCDC127 -1.02 -10.32 -0.49 6.67e-22 Breast cancer; LIHC cis rs992157 0.764 rs2891079 chr2:219184691 A/G cg00012203 chr2:219082015 ARPC2 0.76 10.73 0.5 2.34e-23 Colorectal cancer; LIHC cis rs9457247 1.000 rs430293 chr6:167404958 A/G cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC trans rs459571 0.916 rs467303 chr9:136904835 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.57 -8.77 -0.43 8.79e-17 Platelet distribution width; LIHC cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg00934597 chr7:893267 UNC84A -0.65 -9.76 -0.47 5.33e-20 Perceived unattractiveness to mosquitoes; LIHC cis rs6815814 0.731 rs11735251 chr4:38773057 T/A cg06935464 chr4:38784597 TLR10 0.38 5.96 0.31 6.18e-9 Breast cancer; LIHC cis rs2467099 0.679 rs59867239 chr17:73931787 G/A cg08125733 chr17:73851984 WBP2 0.46 5.85 0.3 1.12e-8 Systolic blood pressure; LIHC cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg15691649 chr6:25882328 NA -0.55 -7.07 -0.36 8.53e-12 Intelligence (multi-trait analysis); LIHC cis rs2708977 1.000 rs1011040 chr2:97212755 A/G cg01950434 chr2:97203154 ARID5A -0.47 -7.2 -0.36 3.8e-12 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs8060686 0.516 rs4567701 chr16:68163662 T/C cg05110241 chr16:68378359 PRMT7 -0.53 -6.21 -0.32 1.5e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs1814175 0.645 rs866427 chr11:49923853 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs1728785 0.818 rs1645984 chr16:68628850 T/C cg02972257 chr16:68554789 NA -0.53 -6.0 -0.31 4.92e-9 Ulcerative colitis; LIHC cis rs6570726 0.935 rs408768 chr6:145871735 A/G cg23711669 chr6:146136114 FBXO30 0.57 10.03 0.48 6.57e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg11644478 chr21:40555479 PSMG1 0.81 10.3 0.49 7.59e-22 Cognitive function; LIHC trans rs2504916 0.830 rs2504934 chr6:160781666 A/G cg04078321 chr6:155635785 TFB1M -0.55 -6.38 -0.33 5.82e-10 Response to hepatitis C treatment; LIHC cis rs12908161 1.000 rs56864281 chr15:85357649 C/A cg17507749 chr15:85114479 UBE2QP1 0.62 6.83 0.35 3.88e-11 Schizophrenia; LIHC cis rs4908768 0.822 rs12122737 chr1:8616404 C/A cg20416874 chr1:8611966 RERE 0.59 9.5 0.46 3.81e-19 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2404602 0.647 rs11072636 chr15:77185786 A/G cg23625390 chr15:77176239 SCAPER -0.57 -9.77 -0.47 4.96e-20 Blood metabolite levels; LIHC cis rs9522267 0.535 rs9515453 chr13:112234612 T/C cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs72781680 1.000 rs72781667 chr2:24225667 A/G cg08917208 chr2:24149416 ATAD2B 0.87 7.73 0.39 1.21e-13 Lymphocyte counts; LIHC cis rs9733 0.565 rs11804276 chr1:150685761 T/A cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs2991971 1.000 rs518365 chr1:46010652 A/G cg15605315 chr1:45957053 TESK2 0.44 5.84 0.3 1.19e-8 High light scatter reticulocyte count; LIHC trans rs1814175 0.817 rs4881645 chr11:49791168 G/A cg03929089 chr4:120376271 NA -0.9 -18.39 -0.71 5.32e-53 Height; LIHC cis rs2455799 0.613 rs4467435 chr3:15791671 A/G cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs12711979 0.584 rs11694096 chr2:3868113 G/A cg17052675 chr2:3827356 NA -0.54 -10.63 -0.5 5.5e-23 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs17685 0.753 rs1104879 chr7:75685568 C/T cg16684958 chr7:75615977 POR 0.5 8.51 0.42 5.35e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg16405210 chr4:1374714 KIAA1530 -0.41 -6.27 -0.32 1.08e-9 Obesity-related traits; LIHC cis rs17384381 0.953 rs1498374 chr1:85787334 C/T cg16011679 chr1:85725395 C1orf52 0.84 9.0 0.44 1.54e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.61 0.8 1.08e-77 Prudent dietary pattern; LIHC trans rs75804782 0.641 rs55740938 chr2:239332647 G/A cg01134436 chr17:81009848 B3GNTL1 0.84 6.81 0.35 4.34e-11 Morning vs. evening chronotype;Chronotype; LIHC trans rs1814175 0.616 rs10839388 chr11:49842603 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -19.81 -0.73 1e-58 Height; LIHC cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.11 -15.49 -0.64 2.29e-41 Gut microbiome composition (summer); LIHC cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg02475777 chr4:1388615 CRIPAK 0.53 8.07 0.4 1.19e-14 Longevity; LIHC cis rs7188861 1.000 rs731774 chr16:11456266 C/T cg01510278 chr16:11456238 NA -0.49 -6.08 -0.31 3.23e-9 HDL cholesterol; LIHC cis rs2273669 0.667 rs2145763 chr6:109306963 C/A cg05315195 chr6:109294784 ARMC2 -0.53 -5.75 -0.3 1.99e-8 Prostate cancer; LIHC cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg07424592 chr7:64974309 NA -0.79 -9.28 -0.45 1.95e-18 Diabetic kidney disease; LIHC cis rs7044106 0.762 rs10760112 chr9:123467570 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.22 0.52 4.5e-25 Hip circumference adjusted for BMI; LIHC trans rs1814175 0.817 rs11493756 chr11:50017885 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.41e-11 Height; LIHC cis rs757081 0.702 rs522619 chr11:17204448 A/G cg15432903 chr11:17409602 KCNJ11 -0.43 -5.94 -0.31 7.08e-9 Systolic blood pressure; LIHC cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg11062466 chr8:58055876 NA 0.51 6.46 0.33 3.53e-10 Developmental language disorder (linguistic errors); LIHC cis rs2842992 0.789 rs2277072 chr6:160182845 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.91 0.54 1.3e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs3096299 0.900 rs4785663 chr16:89434888 G/A cg01788221 chr16:89496183 ANKRD11 -0.38 -5.83 -0.3 1.28e-8 Multiple myeloma (IgH translocation); LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg06873352 chr17:61820015 STRADA 0.75 13.58 0.59 6.97e-34 Prudent dietary pattern; LIHC cis rs11030122 0.702 rs67300156 chr11:3953949 C/T cg18678763 chr11:4115507 RRM1 -0.58 -8.57 -0.42 3.57e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs9916302 0.706 rs667239 chr17:37442241 A/G cg07936489 chr17:37558343 FBXL20 0.86 12.52 0.56 7.02e-30 Glomerular filtration rate (creatinine); LIHC cis rs7523273 0.927 rs2796275 chr1:207950490 C/T cg22525895 chr1:207977042 MIR29B2 0.67 10.53 0.49 1.18e-22 Schizophrenia; LIHC cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg27572855 chr1:25598939 RHD 0.4 8.39 0.41 1.26e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs6840360 0.593 rs10033405 chr4:152474489 A/G cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs897984 0.683 rs8050330 chr16:30824970 C/T cg02466173 chr16:30829666 NA -0.45 -7.56 -0.38 3.76e-13 Dementia with Lewy bodies; LIHC cis rs1274963 0.601 rs784503 chr3:39197731 A/G cg02254461 chr3:39195904 CSRNP1 -0.52 -6.5 -0.33 2.92e-10 Chronic lymphocytic leukemia; LIHC cis rs2073300 0.536 rs6137947 chr20:23414630 C/A cg16736954 chr20:23401023 NAPB 0.7 8.08 0.4 1.15e-14 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs986417 0.901 rs1955698 chr14:61029936 C/T cg27398547 chr14:60952738 C14orf39 0.72 8.27 0.41 3.05e-15 Gut microbiota (bacterial taxa); LIHC cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg24642844 chr7:1081250 C7orf50 -0.91 -8.95 -0.44 2.36e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs875971 1.000 rs6979382 chr7:65886375 C/T cg18876405 chr7:65276391 NA 0.37 6.64 0.34 1.22e-10 Aortic root size; LIHC cis rs7264396 0.635 rs6060719 chr20:34546013 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.72 -0.5 2.52e-23 Total cholesterol levels; LIHC cis rs35110281 0.805 rs162402 chr21:44963418 G/C cg01579765 chr21:45077557 HSF2BP -0.32 -5.89 -0.3 8.99e-9 Mean corpuscular volume; LIHC cis rs67981189 0.593 rs221917 chr14:71590003 C/T cg15816911 chr14:71606274 NA -0.42 -7.0 -0.35 1.4e-11 Schizophrenia; LIHC cis rs965469 0.895 rs6051729 chr20:3290615 A/G cg25506879 chr20:3388711 C20orf194 -0.56 -6.84 -0.35 3.73e-11 IFN-related cytopenia; LIHC cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg03517284 chr6:25882590 NA -0.69 -8.43 -0.41 9.55e-16 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg00280220 chr17:61926910 NA 0.42 6.84 0.35 3.66e-11 Prudent dietary pattern; LIHC cis rs40363 0.645 rs250627 chr16:3527050 G/A cg22508957 chr16:3507546 NAT15 0.52 9.2 0.45 3.72e-18 Tuberculosis; LIHC cis rs509477 1.000 rs7245165 chr18:32567007 C/A cg23791764 chr18:32556832 MAPRE2 0.53 7.57 0.38 3.46e-13 Cerebrospinal fluid AB1-42 levels; LIHC cis rs116248771 0.691 rs2363658 chr3:158395866 G/C cg16708174 chr3:158430962 RARRES1 0.49 6.53 0.33 2.32e-10 diarrhoeal disease at age 2; LIHC cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg24549020 chr5:56110836 MAP3K1 0.51 6.55 0.33 2.07e-10 Initial pursuit acceleration; LIHC cis rs875971 0.545 rs73142233 chr7:65686280 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.19 0.36 4.2e-12 Aortic root size; LIHC cis rs243505 0.660 rs3779038 chr7:148542822 C/T cg09806900 chr7:148480153 CUL1 0.43 6.07 0.31 3.42e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11758351 0.587 rs16891466 chr6:26235737 G/A cg03854865 chr6:26224070 HIST1H3E 0.59 6.49 0.33 3.04e-10 Gout;Renal underexcretion gout; LIHC cis rs2404602 0.716 rs67920045 chr15:76800084 G/A cg03037974 chr15:76606532 NA 0.74 14.47 0.62 2.37e-37 Blood metabolite levels; LIHC cis rs896854 0.517 rs9643353 chr8:95957063 A/G cg13393036 chr8:95962371 TP53INP1 0.37 7.64 0.38 2.26e-13 Type 2 diabetes; LIHC cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg23758822 chr17:41437982 NA 0.94 17.71 0.69 2.79e-50 Menopause (age at onset); LIHC cis rs911119 0.913 rs6048924 chr20:23578996 G/A cg16589663 chr20:23618590 CST3 0.66 6.89 0.35 2.7e-11 Chronic kidney disease; LIHC cis rs2455601 0.608 rs10840137 chr11:8890079 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -8.38 -0.41 1.36e-15 Schizophrenia; LIHC cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg04267008 chr7:1944627 MAD1L1 -0.62 -9.88 -0.47 2.06e-20 Bipolar disorder and schizophrenia; LIHC cis rs55823223 0.702 rs3785437 chr17:73906222 G/T cg06969265 chr17:73775802 H3F3B 0.78 6.86 0.35 3.31e-11 Psoriasis; LIHC cis rs12586317 0.547 rs74462850 chr14:35500093 G/T cg05294307 chr14:35346193 BAZ1A -0.5 -7.52 -0.38 4.91e-13 Psoriasis; LIHC trans rs10242455 0.702 rs2293256 chr7:99057701 A/G cg09045935 chr12:6379348 NA -0.68 -6.69 -0.34 9.35e-11 Blood metabolite levels; LIHC cis rs2806561 0.894 rs628106 chr1:23537685 C/T cg19743168 chr1:23544995 NA 0.42 7.97 0.4 2.39e-14 Height; LIHC cis rs7216064 1.000 rs6504548 chr17:65886048 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.64 -0.46 1.31e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs10761482 0.601 rs10733764 chr10:62210345 C/G cg17314160 chr12:110399253 GIT2 -0.4 -6.16 -0.32 2.07e-9 Schizophrenia; LIHC cis rs4927850 0.752 rs7624460 chr3:195748530 C/T cg00031303 chr3:195681400 NA 0.32 5.76 0.3 1.85e-8 Pancreatic cancer; LIHC cis rs10752881 1.000 rs10737237 chr1:182989269 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.41 0.49 3.07e-22 Colorectal cancer; LIHC cis rs10751667 0.666 rs6597957 chr11:982294 T/A cg06064525 chr11:970664 AP2A2 -0.55 -14.45 -0.62 2.88e-37 Alzheimer's disease (late onset); LIHC cis rs4819052 0.851 rs7276591 chr21:46680156 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.65 0.53 1.2e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7395581 0.798 rs10769252 chr11:47343955 A/G cg25783544 chr11:47291846 MADD 0.42 6.02 0.31 4.51e-9 HDL cholesterol; LIHC cis rs2288073 0.965 rs36101491 chr2:24387532 C/T cg06627628 chr2:24431161 ITSN2 -0.6 -7.68 -0.38 1.66e-13 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs35883536 0.967 rs2783689 chr1:101092411 C/G cg14515779 chr1:101123966 NA 0.63 11.7 0.53 7.93e-27 Monocyte count; LIHC trans rs9951602 1.000 rs1903723 chr18:76646571 A/G cg02800362 chr5:177631904 HNRNPAB 0.6 8.34 0.41 1.79e-15 Obesity-related traits; LIHC cis rs6951245 0.938 rs11764937 chr7:1092074 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -5.85 -0.3 1.18e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs753778 0.602 rs9792 chr8:142205237 C/T cg18755752 chr8:142205143 DENND3 0.36 6.6 0.34 1.54e-10 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs1008375 1.000 rs11947857 chr4:17691047 T/C cg16339924 chr4:17578868 LAP3 -0.46 -5.8 -0.3 1.52e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2933343 1.000 rs6785869 chr3:128643144 G/A cg25356066 chr3:128598488 ACAD9 0.53 6.97 0.35 1.64e-11 IgG glycosylation; LIHC cis rs1580019 0.885 rs3801331 chr7:32497039 A/G cg06627557 chr7:32535165 LSM5;AVL9 -0.98 -16.5 -0.67 2.13e-45 Cognitive ability; LIHC cis rs6939532 0.522 rs4712981 chr6:26361430 C/T cg14345882 chr6:26364793 BTN3A2 0.39 5.76 0.3 1.88e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg16926213 chr1:1841314 NA 0.33 5.97 0.31 5.86e-9 Body mass index; LIHC cis rs7586673 0.930 rs2884364 chr2:161977647 G/A cg16506815 chr2:162101123 NA 0.5 8.26 0.41 3.13e-15 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.532 rs744336 chr15:76674624 T/C cg03037974 chr15:76606532 NA 0.68 12.74 0.57 1.1e-30 Blood metabolite levels; LIHC cis rs8062405 1.000 rs3888190 chr16:28889486 C/A cg00204512 chr16:28754710 NA 0.33 6.15 0.32 2.13e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs801193 0.901 rs4273746 chr7:66301111 C/T cg11764359 chr7:65958608 NA -0.67 -8.91 -0.43 3.19e-17 Aortic root size; LIHC cis rs9303401 0.659 rs17822908 chr17:56801778 T/C cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg21724239 chr8:58056113 NA 0.63 7.52 0.38 4.88e-13 Developmental language disorder (linguistic errors); LIHC cis rs116095464 0.558 rs6555056 chr5:226222 T/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs244293 0.931 rs244370 chr17:53185267 G/A cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs344364 0.511 rs1742467 chr16:1950187 G/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs34172651 0.917 rs35283675 chr16:24820393 A/G cg00152838 chr16:24741724 TNRC6A -0.47 -6.28 -0.32 1.01e-9 Intelligence (multi-trait analysis); LIHC cis rs11148252 0.904 rs7990581 chr13:53019433 A/G cg00495681 chr13:53174319 NA 0.42 6.99 0.35 1.41e-11 Lewy body disease; LIHC cis rs6448317 0.954 rs13116026 chr4:24922242 T/A cg21108841 chr4:24914750 CCDC149 -0.5 -6.32 -0.32 8.24e-10 Heschl's gyrus morphology; LIHC cis rs769267 0.930 rs3794993 chr19:19611550 G/T cg26732615 chr19:19648335 CILP2;YJEFN3 0.4 6.05 0.31 3.81e-9 Tonsillectomy; LIHC cis rs589448 0.902 rs528974 chr12:69765918 A/T cg19645103 chr12:69753606 YEATS4 -0.39 -5.87 -0.3 1.02e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs4834770 1.000 rs878375 chr4:120237574 T/C cg09307838 chr4:120376055 NA 0.42 6.24 0.32 1.26e-9 Blood protein levels; LIHC cis rs2243480 1.000 rs1796220 chr7:66062100 C/T cg18252515 chr7:66147081 NA -1.33 -18.21 -0.7 2.75e-52 Diabetic kidney disease; LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs8180040 0.652 rs13077398 chr3:47011120 G/C cg27129171 chr3:47204927 SETD2 0.62 10.8 0.5 1.4e-23 Colorectal cancer; LIHC cis rs7208859 0.623 rs73271842 chr17:29137155 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11229555 0.609 rs12575080 chr11:58224917 A/G cg15696309 chr11:58395628 NA -0.64 -7.36 -0.37 1.38e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs8017423 1.000 rs8015379 chr14:90679432 C/T cg14092571 chr14:90743983 NA -0.36 -5.76 -0.3 1.88e-8 Mortality in heart failure; LIHC cis rs2404602 0.598 rs11634019 chr15:76634680 A/G cg23625390 chr15:77176239 SCAPER -0.43 -6.57 -0.33 1.9e-10 Blood metabolite levels; LIHC cis rs2439831 0.850 rs16950562 chr15:44036364 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.52 0.42 5.27e-16 Lung cancer in ever smokers; LIHC trans rs10242455 0.571 rs73713594 chr7:99326498 A/G cg09045935 chr12:6379348 NA 0.73 6.07 0.31 3.48e-9 Blood metabolite levels; LIHC cis rs2439831 0.850 rs3825783 chr15:44102309 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.45 0.42 8.23e-16 Lung cancer in ever smokers; LIHC cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg24879335 chr3:133465180 TF 0.28 6.36 0.33 6.64e-10 Iron status biomarkers; LIHC trans rs1945213 0.694 rs34390414 chr11:55863367 T/G cg03929089 chr4:120376271 NA 0.56 7.28 0.37 2.31e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg16405210 chr4:1374714 KIAA1530 -0.84 -13.66 -0.59 3.47e-34 Longevity; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs7572733 0.534 rs1589162 chr2:198782692 A/G cg03934865 chr2:198174659 NA 0.46 6.73 0.34 7.14e-11 Dermatomyositis; LIHC cis rs9911578 0.813 rs8066773 chr17:56601552 A/G cg12560992 chr17:57184187 TRIM37 0.83 13.4 0.59 3.42e-33 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.621 rs57803026 chr12:29497506 G/A cg12903224 chr12:29470962 FAR2 -0.42 -6.66 -0.34 1.12e-10 QT interval; LIHC cis rs9303401 0.659 rs62083410 chr17:56964386 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.34 0.56 3.31e-29 Cognitive test performance; LIHC cis rs9814567 0.964 rs9815894 chr3:134282796 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7927771 0.800 rs55876153 chr11:47416636 G/A cg20307385 chr11:47447363 PSMC3 -0.46 -5.94 -0.31 7.17e-9 Subjective well-being; LIHC cis rs1799949 0.965 rs8067269 chr17:41235799 C/T cg25072359 chr17:41440525 NA 0.37 6.09 0.31 3.11e-9 Menopause (age at onset); LIHC cis rs1707322 0.716 rs28370457 chr1:46172062 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8084351 0.569 rs1078459 chr18:50776291 T/G cg24270629 chr18:50823537 DCC -0.47 -7.1 -0.36 7.36e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12414872 chr3:52030010 RPL29 0.46 6.35 0.32 6.91e-10 Lung function (FEV1/FVC); LIHC cis rs72627509 0.629 rs1718824 chr4:57903747 A/C cg16868167 chr4:57843880 C4orf14;POLR2B 0.49 7.36 0.37 1.36e-12 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs12701220 0.655 rs9638973 chr7:1133678 A/G cg16145915 chr7:1198662 ZFAND2A -0.35 -7.04 -0.36 1.08e-11 Bronchopulmonary dysplasia; LIHC cis rs12744310 0.887 rs12022655 chr1:41816319 G/T cg03962019 chr1:41807865 NA 0.38 6.12 0.31 2.54e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2303759 0.709 rs7256363 chr19:49827804 C/T cg22590775 chr19:49891494 CCDC155 0.47 7.47 0.37 6.79e-13 Multiple sclerosis; LIHC cis rs7552167 0.925 rs78312791 chr1:24513613 C/A cg01960748 chr1:24522592 NA 0.8 9.75 0.47 5.79e-20 Psoriasis vulgaris; LIHC cis rs589448 0.902 rs2603089 chr12:69776800 C/T cg22834771 chr12:69754056 YEATS4 0.53 9.76 0.47 5.11e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs4908768 0.906 rs74324642 chr1:8620172 A/C cg25722041 chr1:8623473 RERE 0.43 6.05 0.31 3.71e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1552244 0.554 rs2272118 chr3:10049287 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.53 -0.38 4.43e-13 Alzheimer's disease; LIHC cis rs920590 0.758 rs62496731 chr8:19659543 C/G cg17834443 chr8:19674713 INTS10 0.49 7.27 0.37 2.53e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs7408868 0.908 rs2074619 chr19:15276919 G/A cg14696996 chr19:15285081 NOTCH3 0.53 7.1 0.36 7.41e-12 Pulse pressure; LIHC cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.97 12.35 0.56 3.17e-29 Alzheimer's disease; LIHC trans rs7246657 0.943 rs713256 chr19:37865365 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs539514 0.690 rs4885345 chr13:76318453 C/T cg04757411 chr13:76259545 LMO7 0.48 8.43 0.41 1e-15 Type 1 diabetes; LIHC cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.52 0.33 2.45e-10 Bipolar disorder; LIHC cis rs360798 0.512 rs2710642 chr2:63149557 G/A cg17519650 chr2:63277830 OTX1 0.57 8.7 0.43 1.47e-16 Coronary artery disease; LIHC cis rs7961581 0.748 rs6421232 chr12:71622905 C/T cg05756094 chr12:71608604 NA 0.41 6.69 0.34 9e-11 Type 2 diabetes; LIHC cis rs208520 1.000 rs72884017 chr6:66992513 T/G cg07460842 chr6:66804631 NA 0.68 7.32 0.37 1.8e-12 Exhaled nitric oxide output; LIHC cis rs6952808 0.534 rs1113736 chr7:1992992 T/C cg19016816 chr7:1267987 NA 0.28 6.21 0.32 1.54e-9 Bipolar disorder and schizophrenia; LIHC trans rs916888 0.821 rs70602 chr17:44859715 T/C cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1904096 0.506 rs17021463 chr4:95224812 T/G cg11021082 chr4:95130006 SMARCAD1 -0.48 -8.79 -0.43 7.5e-17 Type 2 diabetes; LIHC cis rs4788570 0.511 rs4788830 chr16:71732267 A/G cg06353428 chr16:71660113 MARVELD3 1.35 13.8 0.6 1e-34 Intelligence (multi-trait analysis); LIHC cis rs7520050 1.000 rs12410070 chr1:46358882 T/C cg03146154 chr1:46216737 IPP -0.39 -6.38 -0.33 5.75e-10 Red blood cell count;Reticulocyte count; LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg18279126 chr7:2041391 MAD1L1 0.39 6.51 0.33 2.63e-10 Bipolar disorder and schizophrenia; LIHC cis rs5769765 0.773 rs138834 chr22:50180497 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.67 -7.19 -0.36 4.06e-12 Schizophrenia; LIHC cis rs59698941 0.943 rs10491278 chr5:132220436 A/C cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs4843747 0.671 rs28451517 chr16:88109127 A/C cg00677901 chr16:88017247 BANP 0.54 8.24 0.41 3.82e-15 Menopause (age at onset); LIHC cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg07061783 chr6:25882402 NA -0.54 -6.72 -0.34 7.6e-11 Intelligence (multi-trait analysis); LIHC cis rs2120019 1.000 rs34237279 chr15:75361121 A/G cg11632617 chr15:75315747 PPCDC -0.45 -6.37 -0.33 6.25e-10 Blood trace element (Zn levels); LIHC cis rs56104184 0.779 rs17272666 chr19:49356294 T/C cg15549821 chr19:49342101 PLEKHA4 -0.99 -9.56 -0.46 2.4e-19 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs1580019 0.563 rs4723169 chr7:32567577 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.61 8.98 0.44 1.88e-17 Cognitive ability; LIHC cis rs7085104 0.513 rs192569 chr10:104577915 T/C cg15744005 chr10:104629667 AS3MT 0.39 8.55 0.42 4.15e-16 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs7772486 0.782 rs7747576 chr6:146277827 C/T cg13319975 chr6:146136371 FBXO30 0.36 5.83 0.3 1.28e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs16854884 0.606 rs60676654 chr3:143734937 A/G cg06585982 chr3:143692056 C3orf58 0.54 7.06 0.36 9.48e-12 Economic and political preferences (feminism/equality); LIHC cis rs2976388 0.669 rs1836633 chr8:143774592 G/A cg06565975 chr8:143823917 SLURP1 0.32 6.02 0.31 4.59e-9 Urinary tract infection frequency; LIHC cis rs9303401 0.580 rs2013166 chr17:56637630 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23572578 chr14:102975895 ANKRD9 -0.54 -6.29 -0.32 9.67e-10 Systolic blood pressure; LIHC trans rs2243480 1.000 rs10807701 chr7:65724686 C/A cg10756647 chr7:56101905 PSPH -1.03 -12.48 -0.56 1.05e-29 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04207741 chr12:57482553 NAB2 -0.45 -6.15 -0.32 2.11e-9 Pancreatic cancer; LIHC cis rs561341 0.609 rs9906443 chr17:30185565 C/T cg13647721 chr17:30228624 UTP6 -0.69 -7.02 -0.35 1.22e-11 Hip circumference adjusted for BMI; LIHC cis rs2302190 0.882 rs3809709 chr17:56590559 C/T cg12560992 chr17:57184187 TRIM37 0.71 9.03 0.44 1.25e-17 Vitamin D levels; LIHC cis rs600806 0.850 rs10745354 chr1:109931908 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs1866706 0.865 rs4757956 chr11:12876666 G/A cg25843174 chr11:12811716 TEAD1 -0.31 -6.53 -0.33 2.32e-10 Intelligence (multi-trait analysis); LIHC cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg12292205 chr6:26970375 C6orf41 -0.48 -8.19 -0.4 5.31e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg23131131 chr22:24373011 LOC391322 -0.6 -8.56 -0.42 3.9e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2370759 1.000 rs11599044 chr10:32615445 A/G cg05361325 chr10:32636312 EPC1 -0.52 -6.47 -0.33 3.39e-10 Sexual dysfunction (female); LIHC cis rs7107174 1.000 rs2510047 chr11:77988668 C/T cg02023728 chr11:77925099 USP35 -0.44 -8.48 -0.42 6.86e-16 Testicular germ cell tumor; LIHC cis rs1892700 0.764 rs13047862 chr21:34873559 A/G cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.97e-8 Educational attainment; LIHC cis rs7264396 0.790 rs6121020 chr20:34252006 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.45 -0.53 6.66e-26 Total cholesterol levels; LIHC cis rs7312933 0.703 rs11181380 chr12:42616040 A/T cg01256987 chr12:42539512 GXYLT1 -0.42 -7.03 -0.36 1.14e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC cis rs7208859 0.623 rs56018041 chr17:29059985 G/A cg14067834 chr17:29058358 SUZ12P 0.69 6.88 0.35 2.8e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6582630 0.555 rs11182217 chr12:38480030 G/A cg26384229 chr12:38710491 ALG10B 0.92 11.74 0.54 5.85e-27 Drug-induced liver injury (flucloxacillin); LIHC cis rs6964587 0.647 rs38801 chr7:92046327 G/T cg17063962 chr7:91808500 NA -0.85 -13.92 -0.6 3.35e-35 Breast cancer; LIHC cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg13012494 chr21:47604986 C21orf56 0.38 5.78 0.3 1.73e-8 Testicular germ cell tumor; LIHC cis rs875971 0.862 rs11765791 chr7:65936574 A/G cg11764359 chr7:65958608 NA 0.76 12.78 0.57 7.43e-31 Aortic root size; LIHC cis rs10791323 0.628 rs1893850 chr11:133705356 T/C cg06766960 chr11:133703094 NA -0.66 -10.98 -0.51 3.27e-24 Childhood ear infection; LIHC cis rs7429990 0.901 rs9825114 chr3:48138082 A/G cg11946769 chr3:48343235 NME6 -0.49 -6.23 -0.32 1.37e-9 Educational attainment (years of education); LIHC cis rs1348850 0.872 rs7559521 chr2:178452328 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.78 -11.76 -0.54 4.72e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs875971 0.862 rs1612452 chr7:65573896 T/A cg11764359 chr7:65958608 NA -0.82 -13.6 -0.59 5.83e-34 Aortic root size; LIHC trans rs2243480 1.000 rs313820 chr7:65574466 A/C cg10756647 chr7:56101905 PSPH 1.07 13.4 0.59 3.25e-33 Diabetic kidney disease; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg02990361 chr1:107599529 PRMT6 -0.68 -11.28 -0.52 2.68e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs909002 0.830 rs10914460 chr1:32113216 T/C cg13919466 chr1:32135498 COL16A1 -0.37 -6.73 -0.34 6.96e-11 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1348850 0.668 rs6705405 chr2:178493713 A/G cg27490568 chr2:178487706 NA 0.7 9.33 0.45 1.37e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg00800038 chr16:89945340 TCF25 -0.66 -10.56 -0.5 9.4e-23 Skin colour saturation; LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs2731664 0.792 rs1130857 chr5:176863519 G/C cg23176889 chr5:176863531 GRK6 -0.71 -12.79 -0.57 7.27e-31 Intelligence (multi-trait analysis); LIHC cis rs10078 0.571 rs890977 chr5:476910 T/C cg08916839 chr5:415575 AHRR 0.61 12.79 0.57 6.97e-31 Fat distribution (HIV); LIHC cis rs60871478 1.000 rs34761279 chr7:794471 A/G cg05535760 chr7:792225 HEATR2 0.93 12.6 0.56 3.66e-30 Cerebrospinal P-tau181p levels; LIHC cis rs1552244 0.882 rs17050699 chr3:10037167 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.66 -10.28 -0.49 9.14e-22 Alzheimer's disease; LIHC trans rs12478296 1.000 rs56162244 chr2:243018690 A/G cg01596870 chr19:55963115 NA -0.65 -9.24 -0.45 2.67e-18 Obesity-related traits; LIHC cis rs2303759 0.551 rs7249040 chr19:49790602 C/T cg22590775 chr19:49891494 CCDC155 0.46 7.36 0.37 1.39e-12 Multiple sclerosis; LIHC cis rs9326248 0.954 rs4938349 chr11:117021923 C/T cg15534755 chr11:117069859 TAGLN 0.36 6.17 0.32 1.99e-9 Blood protein levels; LIHC cis rs7208859 0.623 rs59029591 chr17:29235746 A/C cg13385521 chr17:29058706 SUZ12P 0.85 8.27 0.41 3.03e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10751667 0.643 rs7396046 chr11:937176 T/C cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.56e-13 Alzheimer's disease (late onset); LIHC cis rs35160687 0.644 rs2113615 chr2:86517602 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 0.38 6.02 0.31 4.55e-9 Night sleep phenotypes; LIHC cis rs7089973 0.604 rs10885618 chr10:116617718 A/G cg03647239 chr10:116582469 FAM160B1 0.46 6.75 0.34 6.33e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs35110281 0.607 rs4819212 chr21:44977455 G/A cg04455712 chr21:45112962 RRP1B 0.4 6.71 0.34 7.96e-11 Mean corpuscular volume; LIHC cis rs2153535 0.580 rs969422 chr6:8451780 A/T cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC cis rs13064411 0.696 rs9839921 chr3:113199093 G/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.25 -0.32 1.21e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs9911578 0.967 rs11079354 chr17:56594460 G/A cg12560992 chr17:57184187 TRIM37 -0.97 -17.64 -0.69 5.52e-50 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.534 rs1983448 chr11:49933856 C/A cg15704280 chr7:45808275 SEPT13 -0.97 -19.93 -0.73 3.23e-59 Height; LIHC cis rs9818758 0.607 rs9862483 chr3:49195441 G/A cg06212747 chr3:49208901 KLHDC8B -0.64 -5.75 -0.3 1.96e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs17666538 0.535 rs896522 chr8:616991 A/G cg13264159 chr8:625131 ERICH1 -0.62 -6.31 -0.32 8.6e-10 IgG glycosylation; LIHC cis rs17401966 0.931 rs11585794 chr1:10443867 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.51 -0.33 2.73e-10 Hepatocellular carcinoma; LIHC cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg11644478 chr21:40555479 PSMG1 0.83 10.53 0.49 1.21e-22 Cognitive function; LIHC cis rs7666738 0.830 rs1869082 chr4:98841254 T/A cg05340658 chr4:99064831 C4orf37 0.64 11.68 0.53 9.31e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs1799949 1.000 rs11659028 chr17:41195025 T/A cg05368731 chr17:41323189 NBR1 0.74 12.49 0.56 9.24e-30 Menopause (age at onset); LIHC cis rs7208859 0.623 rs122898 chr17:28905254 C/T cg13385521 chr17:29058706 SUZ12P -0.67 -6.58 -0.34 1.81e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3806843 0.966 rs6891559 chr5:140145206 G/A cg26395211 chr5:140044315 WDR55 -0.41 -6.01 -0.31 4.69e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs644799 0.965 rs11021313 chr11:95506907 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.81 0.47 3.42e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs826838 0.754 rs2387920 chr12:38626351 A/G cg13010199 chr12:38710504 ALG10B 0.59 6.99 0.35 1.44e-11 Heart rate; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs10751667 1.000 rs7395632 chr11:958789 C/T ch.11.42038R chr11:967971 AP2A2 -0.57 -10.47 -0.49 1.97e-22 Alzheimer's disease (late onset); LIHC cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg00149659 chr3:10157352 C3orf10 0.66 6.49 0.33 2.94e-10 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12484590 chr1:156475177 NA 0.48 7.33 0.37 1.66e-12 Cognitive function; LIHC cis rs7412746 0.571 rs12402939 chr1:150615094 A/C cg18016565 chr1:150552671 MCL1 0.59 11.48 0.53 4.85e-26 Melanoma; LIHC cis rs9326248 1.000 rs4938354 chr11:117051165 A/G cg15534755 chr11:117069859 TAGLN 0.37 6.28 0.32 1.04e-9 Blood protein levels; LIHC cis rs1801251 1.000 rs11676216 chr2:233706368 C/T cg25237894 chr2:233734115 C2orf82 -0.58 -11.39 -0.52 1.1e-25 Coronary artery disease; LIHC cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs12216125 0.554 rs6942196 chr6:26072804 A/G cg17691542 chr6:26056736 HIST1H1C 0.41 5.86 0.3 1.11e-8 Iron status biomarkers; LIHC cis rs9814567 1.000 rs7429866 chr3:134236306 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1144333 1.000 rs1340684 chr1:76471146 T/C cg03433033 chr1:76189801 ACADM 0.52 7.58 0.38 3.19e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs611744 0.967 rs673854 chr8:109191838 G/A cg21045802 chr8:109455806 TTC35 0.51 8.7 0.43 1.37e-16 Dupuytren's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24923219 chr11:94964236 SESN3 0.43 6.11 0.31 2.74e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.642 rs10882914 chr10:99142057 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg27297192 chr10:134578999 INPP5A 0.53 7.34 0.37 1.58e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4803468 0.967 rs4802116 chr19:41905540 C/T cg09537434 chr19:41945824 ATP5SL -1.0 -21.04 -0.75 1.16e-63 Height; LIHC cis rs4819052 0.851 rs28442024 chr21:46674475 C/A cg22633049 chr21:46681294 NA -0.36 -6.16 -0.32 2.05e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs274567 0.501 rs274571 chr5:131712125 A/G cg24060327 chr5:131705240 SLC22A5 0.79 12.43 0.56 1.53e-29 Blood metabolite levels; LIHC cis rs933688 1.000 rs889213 chr5:90682151 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.69 0.73 3.11e-58 Smoking behavior; LIHC cis rs11098499 0.954 rs7437420 chr4:120312903 A/G cg09307838 chr4:120376055 NA 0.76 11.67 0.53 1.03e-26 Corneal astigmatism; LIHC cis rs17106184 1.000 rs115072809 chr1:51023860 C/T cg07174182 chr1:51127561 FAF1 -0.66 -7.07 -0.36 8.68e-12 Type 2 diabetes; LIHC cis rs9381040 0.655 rs879491 chr6:41026953 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.13 -0.31 2.41e-9 Alzheimer's disease (late onset); LIHC cis rs1144333 1.000 rs78223982 chr1:76465203 T/C cg03433033 chr1:76189801 ACADM 0.51 7.5 0.38 5.47e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs8017423 0.935 rs3737035 chr14:90745422 T/C cg04374321 chr14:90722782 PSMC1 -0.78 -14.61 -0.62 6.38e-38 Mortality in heart failure; LIHC cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg07092213 chr7:1199455 ZFAND2A -0.45 -6.58 -0.34 1.78e-10 Longevity;Endometriosis; LIHC cis rs7959452 0.640 rs4761233 chr12:69722880 T/C cg22834771 chr12:69754056 YEATS4 -0.49 -8.48 -0.42 6.84e-16 Blood protein levels; LIHC cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg03354898 chr7:1950403 MAD1L1 -0.37 -5.81 -0.3 1.41e-8 Bipolar disorder and schizophrenia; LIHC cis rs882732 1.000 rs8019677 chr14:95040431 C/T cg14866387 chr14:95027382 SERPINA4 -0.44 -6.1 -0.31 2.94e-9 Blood protein levels; LIHC cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg25072359 chr17:41440525 NA 0.37 5.83 0.3 1.3e-8 Menopause (age at onset); LIHC cis rs8180040 0.654 rs4682831 chr3:47027138 A/G cg27129171 chr3:47204927 SETD2 -0.58 -9.41 -0.45 7.29e-19 Colorectal cancer; LIHC cis rs7662987 0.517 rs2851256 chr4:100039549 G/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs17270561 0.609 rs1165208 chr6:25803904 G/A cg17691542 chr6:26056736 HIST1H1C 0.44 5.97 0.31 5.87e-9 Iron status biomarkers; LIHC cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg05368731 chr17:41323189 NBR1 0.73 12.63 0.56 2.82e-30 Menopause (age at onset); LIHC cis rs875971 0.825 rs28480509 chr7:66099224 A/G cg18252515 chr7:66147081 NA 0.47 6.91 0.35 2.45e-11 Aortic root size; LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.41 0.45 7.44e-19 Bipolar disorder; LIHC cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg20887711 chr4:1340912 KIAA1530 -0.48 -7.36 -0.37 1.41e-12 Obesity-related traits; LIHC cis rs1005277 0.522 rs1208681 chr10:38092975 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.48 -0.46 4.57e-19 Extrinsic epigenetic age acceleration; LIHC cis rs9980664 1.000 rs9978280 chr21:34736946 C/A cg04842828 chr21:34696676 IFNAR1 0.46 6.15 0.32 2.21e-9 Cognitive decline (age-related); LIHC cis rs743757 0.697 rs763030 chr3:50528092 G/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.44 6.49 0.33 2.93e-10 Diastolic blood pressure; LIHC cis rs2404602 0.608 rs17361504 chr15:76601871 A/G cg03037974 chr15:76606532 NA 0.87 22.42 0.77 4.06e-69 Blood metabolite levels; LIHC cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg11062466 chr8:58055876 NA 0.4 5.83 0.3 1.29e-8 Developmental language disorder (linguistic errors); LIHC cis rs10489202 0.583 rs203777 chr1:167876616 C/T cg24449463 chr1:168025552 DCAF6 -0.64 -9.52 -0.46 3.16e-19 Schizophrenia; LIHC cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg10295955 chr4:187884368 NA -0.97 -23.17 -0.78 4.65e-72 Lobe attachment (rater-scored or self-reported); LIHC cis rs7106204 0.514 rs2099889 chr11:24255971 A/G ch.11.24196551F chr11:24239977 NA 0.84 12.17 0.55 1.5e-28 Response to Homoharringtonine (cytotoxicity); LIHC cis rs738322 1.000 rs738320 chr22:38568715 G/T cg25457927 chr22:38595422 NA -0.26 -6.22 -0.32 1.46e-9 Cutaneous nevi; LIHC cis rs13118159 0.801 rs7664474 chr4:1329116 T/A cg13395646 chr4:1353034 KIAA1530 -0.4 -5.99 -0.31 5.31e-9 Longevity; LIHC cis rs2882877 0.610 rs1123109 chr2:190444392 C/T cg10752008 chr2:190445175 SLC40A1 -0.61 -7.42 -0.37 9.13e-13 Mean corpuscular hemoglobin concentration; LIHC trans rs804280 0.662 rs11250164 chr8:11610686 C/T cg23780635 chr8:1880114 ARHGEF10 0.29 6.05 0.31 3.83e-9 Myopia (pathological); LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg00280220 chr17:61926910 NA 0.42 6.55 0.33 2.06e-10 Prudent dietary pattern; LIHC cis rs1552244 0.882 rs2030564 chr3:10039044 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg04234412 chr22:24373322 LOC391322 -0.71 -11.02 -0.51 2.34e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1775715 0.870 rs1755085 chr10:32250931 T/C cg14930904 chr10:32216787 ARHGAP12 0.4 7.08 0.36 8.33e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs16957091 0.909 rs3742988 chr15:43016475 A/G cg24196017 chr15:43021976 CDAN1 -0.42 -6.01 -0.31 4.81e-9 MGMT methylation in smokers; LIHC cis rs15676 0.783 rs2977996 chr9:131582625 C/T cg00228799 chr9:131580591 ENDOG 0.47 6.96 0.35 1.73e-11 Blood metabolite levels; LIHC cis rs4780401 0.609 rs55934118 chr16:11820003 G/C cg01061890 chr16:11836724 TXNDC11 -0.66 -10.73 -0.5 2.37e-23 Rheumatoid arthritis; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg24209194 chr3:40518798 ZNF619 0.63 9.71 0.46 7.86e-20 Renal cell carcinoma; LIHC cis rs919433 0.679 rs6737060 chr2:198524885 G/C cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9902453 1.000 rs8065261 chr17:28418041 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.63 -9.62 -0.46 1.5700000000000001e-19 Coffee consumption (cups per day); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg01089589 chr2:10920095 ATP6V1C2 0.42 6.04 0.31 4.09e-9 Bilirubin levels; LIHC cis rs7131987 0.868 rs7958210 chr12:29395181 G/C cg21522988 chr12:29376872 FAR2 0.3 6.93 0.35 2.1e-11 QT interval; LIHC cis rs539514 0.627 rs9544034 chr13:76293764 G/A cg04757411 chr13:76259545 LMO7 -0.47 -8.22 -0.41 4.35e-15 Type 1 diabetes; LIHC cis rs17106184 0.892 rs113730976 chr1:51217085 T/C cg07174182 chr1:51127561 FAF1 -0.64 -7.3 -0.37 2.04e-12 Type 2 diabetes; LIHC trans rs11098499 0.820 rs12503082 chr4:120284317 A/G cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs2404602 0.692 rs2117369 chr15:76748861 A/T cg03037974 chr15:76606532 NA 0.8 16.39 0.66 5.59e-45 Blood metabolite levels; LIHC cis rs950169 0.922 rs4338765 chr15:84916836 G/T cg03959625 chr15:84868606 LOC388152 0.47 6.72 0.34 7.43e-11 Schizophrenia; LIHC cis rs4788570 0.615 rs1423983 chr16:71701248 G/A cg06353428 chr16:71660113 MARVELD3 1.4 14.67 0.62 4.04e-38 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.4e-11 Diabetic kidney disease; LIHC cis rs6942756 1.000 rs11763056 chr7:128960871 C/A cg02491457 chr7:128862824 NA -0.63 -9.01 -0.44 1.51e-17 White matter hyperintensity burden; LIHC cis rs10504229 0.679 rs12375285 chr8:58040084 G/A cg20607798 chr8:58055168 NA 0.48 6.61 0.34 1.5e-10 Developmental language disorder (linguistic errors); LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg06972381 chr11:32851378 PRRG4 0.4 6.5 0.33 2.81e-10 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg03517284 chr6:25882590 NA 0.6 8.07 0.4 1.17e-14 Blood metabolite levels; LIHC cis rs600806 0.778 rs2039694 chr1:109991700 A/G cg23091122 chr1:110024289 SYPL2 -0.52 -6.93 -0.35 2.04e-11 Intelligence (multi-trait analysis); LIHC cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg06453172 chr10:134556979 INPP5A -0.61 -7.44 -0.37 8e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17685 0.712 rs6976236 chr7:75741087 G/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.21 -0.32 1.52e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg13393036 chr8:95962371 TP53INP1 -0.39 -8.73 -0.43 1.17e-16 Type 2 diabetes; LIHC cis rs3829251 0.786 rs7103591 chr11:71237619 T/C cg05163923 chr11:71159392 DHCR7 -0.6 -7.37 -0.37 1.3e-12 Vitamin D levels; LIHC cis rs9467773 1.000 rs2393670 chr6:26535541 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC trans rs7726839 0.540 rs4957080 chr5:644552 A/C cg25482853 chr8:67687455 SGK3 -0.62 -6.26 -0.32 1.18e-9 Obesity-related traits; LIHC cis rs11971779 0.680 rs10271297 chr7:139052310 A/T cg07862535 chr7:139043722 LUC7L2 0.59 10.32 0.49 6.7e-22 Diisocyanate-induced asthma; LIHC cis rs8017423 0.845 rs8005870 chr14:90723172 A/C cg04374321 chr14:90722782 PSMC1 0.76 15.09 0.63 8.84e-40 Mortality in heart failure; LIHC cis rs1577917 0.740 rs2475792 chr6:86392102 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.49 9.43 0.45 6.22e-19 Response to antipsychotic treatment; LIHC cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg18357526 chr6:26021779 HIST1H4A 0.59 8.28 0.41 2.72e-15 Blood metabolite levels; LIHC cis rs10464366 0.544 rs2280667 chr7:39172228 A/C cg18850127 chr7:39170497 POU6F2 0.46 8.09 0.4 1.05e-14 IgG glycosylation; LIHC cis rs6964587 1.000 rs9784993 chr7:91672403 G/A cg17063962 chr7:91808500 NA 1.01 19.45 0.72 2.77e-57 Breast cancer; LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg02290350 chr8:58132656 NA 0.49 10.28 0.49 8.55e-22 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg17158414 chr2:27665306 KRTCAP3 -0.42 -5.76 -0.3 1.83e-8 Total body bone mineral density; LIHC cis rs4148883 0.651 rs10020052 chr4:100086331 C/G cg12011299 chr4:100065546 ADH4 0.38 7.38 0.37 1.23e-12 Alcohol dependence; LIHC cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg03517284 chr6:25882590 NA 0.5 6.19 0.32 1.76e-9 Intelligence (multi-trait analysis); LIHC cis rs7197653 0.748 rs8060690 chr16:68340085 G/T cg09835421 chr16:68378352 PRMT7 -0.89 -9.83 -0.47 3.11e-20 Magnesium levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11662638 chr2:45878864 PRKCE -0.44 -6.36 -0.33 6.35e-10 Systolic blood pressure; LIHC cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg08499158 chr17:42289980 UBTF -0.52 -9.04 -0.44 1.16e-17 Total body bone mineral density; LIHC cis rs9902453 0.904 rs9897794 chr17:28296327 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 13.82 0.6 7.75e-35 Coffee consumption (cups per day); LIHC cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg23283495 chr1:209979779 IRF6 0.42 6.87 0.35 3.08e-11 Cleft lip with or without cleft palate; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20286844 chr1:204485360 MDM4 0.41 6.21 0.32 1.5e-9 Cognitive function; LIHC cis rs10779751 0.690 rs2791659 chr1:11126569 C/A cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs919433 0.963 rs4850429 chr2:198178409 A/G cg10820045 chr2:198174542 NA 0.57 9.51 0.46 3.43e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg00800038 chr16:89945340 TCF25 -0.68 -10.7 -0.5 3.12e-23 Skin colour saturation; LIHC cis rs17376456 1.000 rs10514382 chr5:93566534 G/A cg25358565 chr5:93447407 FAM172A 1.11 9.63 0.46 1.35e-19 Diabetic retinopathy; LIHC cis rs6598163 0.517 rs12366296 chr12:132296824 C/G cg10319629 chr12:132285459 NA -0.43 -7.45 -0.37 7.9e-13 Migraine; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg11494091 chr17:61959527 GH2 0.46 8.32 0.41 2.19e-15 Prudent dietary pattern; LIHC cis rs12893668 0.703 rs4906337 chr14:104040414 C/A cg24130564 chr14:104152367 KLC1 -0.54 -8.8 -0.43 6.79e-17 Reticulocyte count; LIHC cis rs60871478 0.636 rs12534606 chr7:895928 A/G cg05535760 chr7:792225 HEATR2 -0.81 -6.59 -0.34 1.63e-10 Cerebrospinal P-tau181p levels; LIHC cis rs12220238 1.000 rs4320897 chr10:76017732 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.89 0.35 2.77e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.44 -7.37 -0.37 1.29e-12 Height; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.5 -7.18 -0.36 4.4e-12 Lymphocyte counts; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg02592271 chr2:27665507 KRTCAP3 0.44 6.09 0.31 2.99e-9 Total body bone mineral density; LIHC cis rs6964587 0.839 rs13246743 chr7:91453945 G/T cg17063962 chr7:91808500 NA 0.96 17.55 0.69 1.24e-49 Breast cancer; LIHC cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.81e-8 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.850 rs2190808 chr16:89840856 C/T cg00800038 chr16:89945340 TCF25 -0.63 -9.48 -0.46 4.32e-19 Skin colour saturation; LIHC cis rs11190604 1.000 rs2489039 chr10:102328036 T/A cg07080220 chr10:102295463 HIF1AN 0.54 7.33 0.37 1.64e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1401999 0.690 rs6768149 chr3:183636195 T/C cg01324343 chr3:183735012 ABCC5 0.53 8.35 0.41 1.71e-15 Anterior chamber depth; LIHC cis rs11252926 0.502 rs7072510 chr10:455596 C/T cg16346588 chr10:242978 ZMYND11 0.39 6.0 0.31 5.01e-9 Psychosis in Alzheimer's disease; LIHC cis rs986417 1.000 rs2224410 chr14:60970531 T/C cg27398547 chr14:60952738 C14orf39 0.84 9.62 0.46 1.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs12142240 0.698 rs4372193 chr1:46853233 G/T cg14993813 chr1:46806288 NSUN4 -0.66 -5.94 -0.31 6.85e-9 Menopause (age at onset); LIHC cis rs55665837 0.701 rs10766188 chr11:14660826 T/C cg00085434 chr11:14927489 NA 0.42 5.89 0.3 9.38e-9 Vitamin D levels; LIHC cis rs703842 0.928 rs724834 chr12:58180416 G/C cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.22 0.61 2.3e-36 Multiple sclerosis; LIHC cis rs1008375 1.000 rs17507481 chr4:17620066 A/G cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6963495 0.745 rs68153235 chr7:105184832 A/C cg19920283 chr7:105172520 RINT1 0.75 8.57 0.42 3.54e-16 Bipolar disorder (body mass index interaction); LIHC cis rs17106184 1.000 rs114210346 chr1:51398101 G/C cg07174182 chr1:51127561 FAF1 -0.74 -8.35 -0.41 1.69e-15 Type 2 diabetes; LIHC cis rs10504073 0.584 rs55838473 chr8:49948281 C/A cg00325661 chr8:49890786 NA 0.34 7.75 0.39 1.03e-13 Blood metabolite ratios; LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg00091569 chr3:40428383 ENTPD3 0.39 6.6 0.34 1.59e-10 Renal cell carcinoma; LIHC cis rs595982 0.559 rs117227130 chr19:49367959 A/G cg15549821 chr19:49342101 PLEKHA4 -0.63 -5.84 -0.3 1.24e-8 Red cell distribution width; LIHC cis rs10504229 0.679 rs12375445 chr8:58040082 A/G cg02290350 chr8:58132656 NA 0.32 7.07 0.36 8.87e-12 Developmental language disorder (linguistic errors); LIHC trans rs8113308 0.810 rs8105910 chr19:52447068 A/G cg14959425 chr7:20447707 ITGB8 -0.47 -6.1 -0.31 2.88e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs2806561 0.765 rs641032 chr1:23513980 C/T cg12483005 chr1:23474871 LUZP1 -0.43 -6.87 -0.35 3e-11 Height; LIHC cis rs7552404 0.731 rs10873788 chr1:76367857 A/C cg10523679 chr1:76189770 ACADM 0.48 6.51 0.33 2.74e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs589448 0.933 rs2249093 chr12:69753512 G/C cg20891283 chr12:69753455 YEATS4 0.95 22.44 0.77 3.39e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs477895 0.713 rs12575642 chr11:63979643 G/T cg18225595 chr11:63971243 STIP1 0.67 8.47 0.42 7.25e-16 Mean platelet volume; LIHC cis rs7552404 1.000 rs4949872 chr1:76131392 C/G cg22875332 chr1:76189707 ACADM 0.47 6.78 0.34 5.15e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7100689 0.516 rs10887711 chr10:82034842 A/G cg01528321 chr10:82214614 TSPAN14 0.84 11.11 0.52 1.07e-24 Post bronchodilator FEV1; LIHC cis rs17106184 1.000 rs72902765 chr1:51256698 T/G cg07174182 chr1:51127561 FAF1 -0.64 -6.89 -0.35 2.74e-11 Type 2 diabetes; LIHC cis rs9596863 0.861 rs4088520 chr13:54441906 C/T ch.13.53330881F chr13:54432880 NA -0.43 -6.08 -0.31 3.27e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg17971929 chr21:40555470 PSMG1 0.82 9.48 0.46 4.4e-19 Cognitive function; LIHC cis rs10751667 0.666 rs7483273 chr11:951127 T/C ch.11.42038R chr11:967971 AP2A2 0.56 9.97 0.47 1.01e-20 Alzheimer's disease (late onset); LIHC trans rs16875255 0.505 rs7656616 chr4:24187951 A/G cg24654547 chr16:68057165 DUS2L;DDX28 -0.49 -6.12 -0.31 2.51e-9 Parental longevity (combined parental age at death); LIHC cis rs9640161 0.789 rs60283368 chr7:150023258 G/A cg10018233 chr7:150070692 REPIN1 0.57 9.63 0.46 1.4e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg12311346 chr5:56204834 C5orf35 -0.58 -7.6 -0.38 2.92e-13 Initial pursuit acceleration; LIHC cis rs7584330 0.554 rs7573177 chr2:238444467 C/T cg08992911 chr2:238395768 MLPH -0.5 -5.92 -0.31 7.62e-9 Prostate cancer; LIHC cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg05564831 chr3:52568323 NT5DC2 0.36 5.8 0.3 1.51e-8 Bipolar disorder; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.97 24.16 0.79 6.12e-76 Prudent dietary pattern; LIHC trans rs6951245 0.554 rs76243429 chr7:1152543 C/T cg13565492 chr6:43139072 SRF -0.76 -7.06 -0.36 9.43e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6701037 0.566 rs10489326 chr1:175134677 A/G cg00321850 chr1:175162397 KIAA0040 0.46 7.6 0.38 2.88e-13 Alcohol dependence; LIHC cis rs7546668 1.000 rs10803390 chr1:15865418 G/A cg11706911 chr1:15910989 AGMAT 0.44 6.66 0.34 1.1e-10 Glomerular filtration rate (creatinine); LIHC cis rs34779708 0.966 rs12260130 chr10:35467671 C/T cg04310649 chr10:35416472 CREM -0.43 -5.85 -0.3 1.13e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs801193 0.967 rs2707841 chr7:66157020 A/G cg14393609 chr7:65229607 NA 0.37 5.88 0.3 9.55e-9 Aortic root size; LIHC cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg02891314 chr5:179741120 GFPT2 0.42 5.72 0.3 2.38e-8 Height; LIHC cis rs1419980 0.673 rs1978284 chr12:7771151 G/A cg10578777 chr12:7781093 NA 0.49 8.86 0.43 4.51e-17 HDL cholesterol levels; LIHC cis rs7188697 0.845 rs1981960 chr16:58597289 C/G cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg11644478 chr21:40555479 PSMG1 0.86 11.13 0.52 9.49e-25 Cognitive function; LIHC cis rs3806843 1.000 rs3756342 chr5:140165624 G/A cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.68 -0.5 3.48e-23 Alzheimer's disease; LIHC cis rs7432375 0.901 rs1729951 chr3:136500733 T/G cg21827317 chr3:136751795 NA -0.46 -5.99 -0.31 5.29e-9 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs896854 0.548 rs574183 chr8:95973816 A/G cg09323728 chr8:95962352 TP53INP1 0.31 5.94 0.31 7.09e-9 Type 2 diabetes; LIHC trans rs9914544 0.545 rs4924940 chr17:18800092 T/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.54 -0.33 2.26e-10 Educational attainment (years of education); LIHC cis rs8060686 0.641 rs8058690 chr16:68136622 T/G cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.69e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs6060717 0.536 rs6060699 chr20:34523833 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.57 -7.47 -0.37 6.65e-13 Hip circumference adjusted for BMI; LIHC cis rs3770081 1.000 rs60479377 chr2:86283948 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.96 -11.43 -0.53 7.58e-26 Facial emotion recognition (sad faces); LIHC cis rs1799949 1.000 rs915945 chr17:41179864 C/T cg25072359 chr17:41440525 NA 0.37 5.8 0.3 1.5e-8 Menopause (age at onset); LIHC cis rs11122272 0.735 rs2808600 chr1:231534723 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.94e-23 Hemoglobin concentration; LIHC cis rs11644362 1.000 rs72782620 chr16:12987416 T/A cg06890432 chr16:12997467 SHISA9 -0.4 -6.77 -0.34 5.57e-11 Positive affect;Subjective well-being; LIHC cis rs8084351 0.599 rs11082969 chr18:50680524 C/G cg24270629 chr18:50823537 DCC -0.47 -7.08 -0.36 8.42e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs11229555 0.645 rs10466659 chr11:58190112 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7552404 0.924 rs7535991 chr1:76162624 C/T cg10523679 chr1:76189770 ACADM 0.67 9.95 0.47 1.22e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11053548 0.678 rs12228507 chr12:10174173 G/A cg04314261 chr12:10163030 CLEC12B 0.41 6.24 0.32 1.27e-9 Systolic blood pressure in sickle cell anemia; LIHC cis rs801193 1.000 rs3857688 chr7:66127806 G/A cg00343986 chr7:65444356 GUSB -0.39 -5.84 -0.3 1.2e-8 Aortic root size; LIHC cis rs8067545 0.750 rs4925077 chr17:19982276 C/T cg13482628 chr17:19912719 NA 0.49 8.29 0.41 2.7e-15 Schizophrenia; LIHC cis rs8077889 0.956 rs6503476 chr17:41850163 C/T cg26893861 chr17:41843967 DUSP3 1.02 11.32 0.52 1.91e-25 Triglycerides; LIHC cis rs6502050 0.835 rs4789732 chr17:80131382 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs7927771 0.832 rs1317164 chr11:47419757 G/T cg20135002 chr11:47629003 NA -0.53 -9.08 -0.44 8.63e-18 Subjective well-being; LIHC trans rs11165623 0.564 rs6669908 chr1:96998261 G/A cg10631902 chr5:14652156 NA -0.29 -6.81 -0.35 4.31e-11 Hip circumference;Waist circumference; LIHC cis rs4423214 0.879 rs1792264 chr11:71150247 C/T cg05163923 chr11:71159392 DHCR7 -0.59 -8.14 -0.4 7.28e-15 Vitamin D levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04860157 chr6:36842651 PPIL1 0.46 6.37 0.33 6.02e-10 Lung function (FEV1/FVC); LIHC cis rs2153535 0.541 rs945304 chr6:8442892 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.5 0.42 5.96e-16 Motion sickness; LIHC cis rs4927850 0.723 rs7630825 chr3:195753740 T/C cg12923728 chr3:195709715 SDHAP1 -0.7 -10.22 -0.48 1.45e-21 Pancreatic cancer; LIHC cis rs713477 1.000 rs7149622 chr14:55909402 T/C cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.32e-15 Pediatric bone mineral content (femoral neck); LIHC trans rs6693295 0.711 rs4417032 chr1:246226428 G/A cg22732515 chr19:44031385 ETHE1 0.45 6.28 0.32 1.01e-9 Migraine - clinic-based;Migraine with aura; LIHC cis rs7772486 0.764 rs2265471 chr6:146220250 G/A cg23711669 chr6:146136114 FBXO30 0.63 11.04 0.51 1.88e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.15e-11 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg18252515 chr7:66147081 NA -1.25 -16.77 -0.67 1.7e-46 Diabetic kidney disease; LIHC cis rs6499255 0.903 rs1800566 chr16:69745145 C/T cg15192750 chr16:69999425 NA 0.43 6.37 0.33 5.95e-10 IgE levels; LIHC cis rs2463822 0.858 rs2513037 chr11:62084822 A/T cg06239285 chr11:62104954 ASRGL1 -0.88 -6.95 -0.35 1.9e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg06238570 chr21:40685208 BRWD1 -0.53 -8.68 -0.42 1.68e-16 Cognitive function; LIHC trans rs2243480 1.000 rs1796228 chr7:66033084 G/A cg07424592 chr7:64974309 NA 0.78 8.94 0.44 2.44e-17 Diabetic kidney disease; LIHC cis rs801193 1.000 rs7782320 chr7:66177098 C/T cg00343986 chr7:65444356 GUSB 0.4 5.91 0.3 8.49e-9 Aortic root size; LIHC trans rs116095464 0.867 rs10074958 chr5:230828 C/T cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs1506636 1.000 rs659416 chr7:123401764 A/G cg03229431 chr7:123269106 ASB15 -0.59 -11.6 -0.53 1.89e-26 Plateletcrit;Platelet count; LIHC cis rs9640161 0.673 rs11773351 chr7:150030963 T/C cg10018233 chr7:150070692 REPIN1 0.54 8.29 0.41 2.66e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs72781680 0.846 rs55707417 chr2:24029928 G/A cg08917208 chr2:24149416 ATAD2B 0.96 8.09 0.4 1.06e-14 Lymphocyte counts; LIHC cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg16434002 chr17:42200994 HDAC5 -0.51 -7.31 -0.37 1.88e-12 Total body bone mineral density; LIHC cis rs2257205 0.667 rs77326197 chr17:56905618 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -6.46 -0.33 3.5e-10 Pancreatic cancer; LIHC cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg02353165 chr6:42928485 GNMT 0.91 15.05 0.63 1.28e-39 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg09367891 chr1:107599246 PRMT6 0.69 11.35 0.52 1.45e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg24503407 chr1:205819492 PM20D1 0.87 12.87 0.57 3.59e-31 Menarche (age at onset); LIHC trans rs3812049 0.737 rs790154 chr5:127501235 A/G cg16011800 chr17:1958478 HIC1 -0.46 -6.54 -0.33 2.29e-10 Lymphocyte counts;Red cell distribution width; LIHC cis rs1008375 0.863 rs7680984 chr4:17600884 A/G cg02297831 chr4:17616191 MED28 0.46 7.2 0.36 3.78e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7617773 0.780 rs13066758 chr3:48343877 G/A cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs12701220 0.542 rs6957866 chr7:1111674 G/A cg02733842 chr7:1102375 C7orf50 -0.69 -7.66 -0.38 1.97e-13 Bronchopulmonary dysplasia; LIHC cis rs11148252 0.669 rs4884320 chr13:53006914 T/C cg00495681 chr13:53174319 NA 0.37 5.93 0.31 7.28e-9 Lewy body disease; LIHC cis rs1865721 1.000 rs8096298 chr18:73187608 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.57 -0.38 3.61e-13 Intelligence; LIHC cis rs6545883 0.929 rs10200055 chr2:61628017 T/A cg14146966 chr2:61757674 XPO1 -0.44 -7.53 -0.38 4.6e-13 Tuberculosis; LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg02475777 chr4:1388615 CRIPAK 0.39 6.0 0.31 5.13e-9 Obesity-related traits; LIHC cis rs11229555 0.645 rs7117080 chr11:58178677 C/G cg15696309 chr11:58395628 NA -0.64 -7.68 -0.38 1.67e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2070488 0.965 rs9877282 chr3:38541452 A/G cg24069376 chr3:38537580 EXOG -0.43 -7.94 -0.39 2.98e-14 Electrocardiographic conduction measures; LIHC cis rs7091068 0.616 rs1409336 chr10:95479674 T/G cg20715218 chr10:95462985 C10orf4 0.54 5.82 0.3 1.32e-8 Urinary tract infection frequency; LIHC cis rs2180341 0.781 rs6913350 chr6:127570560 C/T cg24812749 chr6:127587940 RNF146 0.66 9.76 0.47 5.32e-20 Breast cancer; LIHC cis rs4908768 0.680 rs11121225 chr1:8816438 G/A cg20416874 chr1:8611966 RERE 0.49 6.48 0.33 3.18e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs9354352 0.935 rs9345749 chr6:66699892 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.53 -7.88 -0.39 4.34e-14 Initial pursuit acceleration in psychotic disorders; LIHC cis rs12887734 0.546 rs4900597 chr14:104266664 A/G cg01849466 chr14:104193079 ZFYVE21 0.39 6.07 0.31 3.41e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs798554 0.644 rs7783400 chr7:2894434 A/C cg04166393 chr7:2884313 GNA12 -0.46 -7.56 -0.38 3.78e-13 Height; LIHC cis rs9790314 0.586 rs16832246 chr3:161109916 A/G cg17135325 chr3:160939158 NMD3 -0.5 -7.39 -0.37 1.15e-12 Morning vs. evening chronotype; LIHC cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg05665937 chr4:1216051 CTBP1 0.45 5.82 0.3 1.32e-8 Obesity-related traits; LIHC cis rs875971 1.000 rs12532998 chr7:65967459 A/C cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.54e-9 Aortic root size; LIHC cis rs6545883 0.929 rs778140 chr2:61682976 C/T cg14146966 chr2:61757674 XPO1 0.48 8.31 0.41 2.23e-15 Tuberculosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27499259 chr13:28400924 NA 0.44 6.08 0.31 3.2e-9 Pancreatic cancer; LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.15 0.55 1.79e-28 Prudent dietary pattern; LIHC cis rs10792665 0.640 rs7947363 chr11:82620671 C/T cg24227371 chr11:82718527 RAB30 -0.27 -6.13 -0.31 2.46e-9 Obesity-related traits; LIHC cis rs5769707 0.681 rs9616329 chr22:50026314 G/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.43 -0.41 9.58e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7666738 0.830 rs7689495 chr4:98920152 T/C cg05340658 chr4:99064831 C4orf37 0.65 12.12 0.55 2.24e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs80282103 0.618 rs74117850 chr10:1165777 T/C cg08668510 chr10:1095578 IDI1 0.63 6.06 0.31 3.51e-9 Glomerular filtration rate (creatinine); LIHC cis rs1355223 0.902 rs7130325 chr11:34750959 A/G cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.46 -0.33 3.61e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1355223 0.552 rs2421743 chr11:34882840 C/T cg06937548 chr11:34938143 PDHX;APIP 0.41 5.85 0.3 1.17e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1499614 1.000 rs1882655 chr7:66147057 T/C cg12463550 chr7:65579703 CRCP -0.66 -6.92 -0.35 2.21e-11 Gout; LIHC cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg21280719 chr6:42927975 GNMT -0.37 -7.96 -0.4 2.53e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs870825 0.616 rs6552809 chr4:185643984 G/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC trans rs72960926 0.744 rs114317207 chr6:74955867 C/T cg07247405 chr1:2484626 LOC115110 0.53 6.37 0.33 6.01e-10 Metabolite levels (MHPG); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08269949 chr6:26538502 HMGN4 0.48 7.41 0.37 9.97e-13 Cognitive function; LIHC cis rs7945705 0.967 rs10769970 chr11:8917937 A/G cg12365402 chr11:9010492 NRIP3 0.31 7.91 0.39 3.7e-14 Hemoglobin concentration; LIHC cis rs11690935 0.959 rs66835971 chr2:172677459 G/A cg13550731 chr2:172543902 DYNC1I2 -0.92 -17.06 -0.68 1.14e-47 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg19614157 chr2:24150126 ATAD2B 0.51 6.37 0.33 6.23e-10 Hepatitis; LIHC trans rs3783890 1.000 rs59713276 chr14:93738204 T/C cg02802420 chr16:69363236 PDF;COG8 0.33 6.42 0.33 4.63e-10 Body mass index; LIHC cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg23758822 chr17:41437982 NA 0.94 17.97 0.7 2.51e-51 Menopause (age at onset); LIHC cis rs9443189 0.570 rs72888705 chr6:76403114 A/G cg01950844 chr6:76311363 SENP6 0.87 10.9 0.51 6.08e-24 Prostate cancer; LIHC cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9381040 0.610 rs9357345 chr6:41025118 G/C cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.77 -0.3 1.82e-8 Alzheimer's disease (late onset); LIHC cis rs875971 0.862 rs6460279 chr7:65662761 T/C cg18252515 chr7:66147081 NA 0.43 6.16 0.32 2.08e-9 Aortic root size; LIHC cis rs7582180 0.629 rs11686649 chr2:100946701 T/C cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.97e-16 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.845 rs2042511 chr12:29408780 C/T cg21486233 chr12:29375141 FAR2 0.3 5.82 0.3 1.36e-8 QT interval; LIHC cis rs79149102 0.737 rs113915655 chr15:75219722 T/C cg16226627 chr15:75307476 SCAMP5 0.44 6.22 0.32 1.41e-9 Lung cancer; LIHC trans rs11098499 0.863 rs2306457 chr4:120472839 T/A cg25214090 chr10:38739885 LOC399744 0.6 9.64 0.46 1.31e-19 Corneal astigmatism; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.87 0.39 4.61e-14 Prudent dietary pattern; LIHC cis rs7772486 0.720 rs4896844 chr6:146075224 T/C cg13319975 chr6:146136371 FBXO30 0.41 6.73 0.34 7.38e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02809263 chr1:70671218 LRRC40;SFRS11 0.44 6.24 0.32 1.3e-9 Pancreatic cancer; LIHC cis rs3018712 0.532 rs2510397 chr11:68419559 A/G cg16797656 chr11:68205561 LRP5 -0.44 -5.79 -0.3 1.56e-8 Total body bone mineral density; LIHC cis rs7582180 0.591 rs62148360 chr2:101006319 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.34 0.41 1.88e-15 Intelligence (multi-trait analysis); LIHC cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg26116260 chr4:7069785 GRPEL1 0.96 18.06 0.7 1.09e-51 Monocyte percentage of white cells; LIHC cis rs7843479 0.582 rs11135743 chr8:21803008 A/G cg17168535 chr8:21777572 XPO7 0.58 10.09 0.48 4.04e-21 Mean corpuscular volume; LIHC trans rs875971 0.571 rs78668714 chr7:65939451 G/A cg26939375 chr7:64535504 NA 0.41 6.49 0.33 2.98e-10 Aortic root size; LIHC cis rs2204008 0.782 rs117824012 chr12:38215517 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs1008375 0.866 rs2109518 chr4:17572162 G/A cg02297831 chr4:17616191 MED28 0.47 6.93 0.35 2.14e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2281845 0.507 rs942703 chr1:201092979 A/G cg06714761 chr1:201096289 NA -0.38 -6.62 -0.34 1.36e-10 Permanent tooth development; LIHC cis rs765787 0.530 rs2433227 chr15:45517119 A/T cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs7665147 1 rs7665147 chr4:57767327 T/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.54 -7.9 -0.39 3.88e-14 Platelet count; LIHC cis rs9300255 0.543 rs655293 chr12:123528405 G/A cg05973401 chr12:123451056 ABCB9 0.47 6.12 0.31 2.6e-9 Neutrophil percentage of white cells; LIHC cis rs1127311 0.905 rs6702449 chr1:154583210 A/C cg17218026 chr1:154582156 ADAR 0.36 7.2 0.36 3.78e-12 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs1552244 0.554 rs6768339 chr3:10006079 G/T cg02579736 chr3:10068473 FANCD2;CIDECP -0.55 -7.92 -0.39 3.28e-14 Alzheimer's disease; LIHC cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.54 -0.59 9.42e-34 Vitiligo; LIHC cis rs600806 0.815 rs10858089 chr1:109926828 T/C cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs3823572 0.511 rs2971982 chr7:133657698 C/T cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.08 11.63 0.53 1.49e-26 Platelet count; LIHC cis rs3808502 0.527 rs2736374 chr8:11113828 A/G cg21756720 chr8:11724777 CTSB 0.5 5.92 0.3 7.86e-9 Neuroticism; LIHC trans rs459571 0.792 rs55923934 chr9:136888233 C/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.6 -9.32 -0.45 1.51e-18 Platelet distribution width; LIHC cis rs2976388 0.647 rs2082801 chr8:143786461 A/G cg06565975 chr8:143823917 SLURP1 0.34 6.35 0.32 6.98e-10 Urinary tract infection frequency; LIHC cis rs7216064 0.953 rs11871285 chr17:65840809 G/T cg12091567 chr17:66097778 LOC651250 -0.67 -9.38 -0.45 9.54e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs644799 0.965 rs573758 chr11:95539591 G/T cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12824058 0.831 rs1390849 chr12:130811547 A/G cg24229701 chr12:130821962 PIWIL1 0.44 6.78 0.34 5.4e-11 Menopause (age at onset); LIHC cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg21644426 chr2:191273491 MFSD6 0.54 7.57 0.38 3.41e-13 Pulse pressure; LIHC cis rs9660992 0.662 rs12092492 chr1:205251880 T/C cg21545522 chr1:205238299 TMCC2 0.35 6.74 0.34 6.72e-11 Mean corpuscular volume;Mean platelet volume; LIHC cis rs798554 1.000 rs798562 chr7:2757938 C/T cg19717773 chr7:2847554 GNA12 -0.39 -6.15 -0.32 2.15e-9 Height; LIHC cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.22 0.45 3.17e-18 Bipolar disorder; LIHC cis rs561341 0.609 rs11658984 chr17:30186612 C/T cg13647721 chr17:30228624 UTP6 -0.69 -7.11 -0.36 6.92e-12 Hip circumference adjusted for BMI; LIHC cis rs2479724 0.776 rs2250428 chr6:41832772 T/A cg17623882 chr6:41773611 USP49 -0.55 -8.81 -0.43 6.23e-17 Menarche (age at onset); LIHC cis rs2257205 0.667 rs6503881 chr17:56911251 C/T cg12560992 chr17:57184187 TRIM37 0.66 7.24 0.36 3.03e-12 Pancreatic cancer; LIHC cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg06634786 chr22:41940651 POLR3H -0.81 -8.67 -0.42 1.78e-16 Vitiligo; LIHC trans rs7677751 0.806 rs6836215 chr4:55102741 T/C cg17183009 chr3:120277827 NA 0.52 6.23 0.32 1.38e-9 Corneal astigmatism; LIHC cis rs4934494 0.911 rs6586213 chr10:91416084 G/A cg19698084 chr10:91461284 KIF20B -0.45 -6.18 -0.32 1.85e-9 Red blood cell count; LIHC cis rs1577917 0.771 rs4441928 chr6:86241894 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 11.96 0.54 8.58e-28 Response to antipsychotic treatment; LIHC cis rs4764487 0.687 rs3181300 chr12:6345199 C/T cg08284733 chr12:6341482 CD9 0.33 5.74 0.3 2.07e-8 Mean platelet volume; LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg24209194 chr3:40518798 ZNF619 0.62 9.54 0.46 2.84e-19 Renal cell carcinoma; LIHC cis rs35110281 0.748 rs9981460 chr21:45030965 T/A cg04455712 chr21:45112962 RRP1B 0.47 7.85 0.39 5.34e-14 Mean corpuscular volume; LIHC cis rs858239 0.539 rs6971673 chr7:23159523 C/G cg23682824 chr7:23144976 KLHL7 0.43 6.54 0.33 2.21e-10 Cerebrospinal fluid biomarker levels; LIHC trans rs6539288 0.803 rs10778517 chr12:107341664 G/T cg19431293 chr4:1319136 MAEA -0.44 -7.01 -0.35 1.3e-11 Total body bone mineral density; LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg18306943 chr3:40428807 ENTPD3 0.42 7.38 0.37 1.21e-12 Renal cell carcinoma; LIHC cis rs734999 0.566 rs12748729 chr1:2558740 C/T cg18854424 chr1:2615690 NA -0.33 -7.23 -0.36 3.22e-12 Ulcerative colitis; LIHC trans rs2243480 1.000 rs778691 chr7:65873092 G/C cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs7542091 0.748 rs2357231 chr1:210028454 A/C cg23283495 chr1:209979779 IRF6 -0.37 -6.32 -0.32 8.3e-10 Monobrow; LIHC cis rs769267 0.931 rs15622 chr19:19468734 G/A cg03709012 chr19:19516395 GATAD2A -0.95 -16.46 -0.66 2.89e-45 Tonsillectomy; LIHC cis rs7937682 0.883 rs566647 chr11:111466607 A/G cg09085632 chr11:111637200 PPP2R1B 0.91 11.07 0.51 1.51e-24 Primary sclerosing cholangitis; LIHC cis rs8060686 0.641 rs76646352 chr16:68044797 C/A cg05110241 chr16:68378359 PRMT7 -0.6 -6.85 -0.35 3.53e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg06636001 chr8:8085503 FLJ10661 -0.58 -10.03 -0.48 6.26e-21 Neuroticism; LIHC cis rs950169 0.922 rs12915832 chr15:85111457 C/T cg03959625 chr15:84868606 LOC388152 0.42 5.84 0.3 1.24e-8 Schizophrenia; LIHC cis rs7917772 0.503 rs11191330 chr10:104306160 G/T cg22532475 chr10:104410764 TRIM8 -0.3 -5.94 -0.31 7.18e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg00800038 chr16:89945340 TCF25 -0.6 -9.69 -0.46 9.19e-20 Skin colour saturation; LIHC cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.48 0.46 4.53e-19 Bipolar disorder; LIHC cis rs6951245 1.000 rs6951245 chr7:1058193 G/A cg24642844 chr7:1081250 C7orf50 -0.88 -8.8 -0.43 6.97e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs877282 0.755 rs11253399 chr10:790030 T/A cg22713356 chr15:30763199 NA 1.22 11.52 0.53 3.75e-26 Uric acid levels; LIHC cis rs2404602 0.647 rs12913024 chr15:77145216 C/T cg23625390 chr15:77176239 SCAPER -0.54 -8.97 -0.44 2.02e-17 Blood metabolite levels; LIHC cis rs13108904 0.557 rs1250098 chr4:1238256 A/T cg02475777 chr4:1388615 CRIPAK -0.49 -7.36 -0.37 1.35e-12 Obesity-related traits; LIHC cis rs67311347 0.824 rs59922539 chr3:40337110 G/A cg13409248 chr3:40428643 ENTPD3 0.38 5.84 0.3 1.23e-8 Renal cell carcinoma; LIHC cis rs1385374 0.858 rs11059926 chr12:129294244 A/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.68 0.38 1.73e-13 Systemic lupus erythematosus; LIHC cis rs9733 0.503 rs7556451 chr1:150913142 A/G cg15448220 chr1:150897856 SETDB1 0.39 6.25 0.32 1.22e-9 Tonsillectomy; LIHC cis rs12478296 1.000 rs73007129 chr2:243000555 T/C cg18898632 chr2:242989856 NA -0.7 -8.65 -0.42 2.05e-16 Obesity-related traits; LIHC cis rs763512 0.504 rs11652399 chr17:35869781 G/T cg16670864 chr17:35848621 DUSP14 0.34 5.72 0.3 2.35e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs5753618 0.509 rs5997912 chr22:31593861 A/G cg22777020 chr22:31556080 RNF185 -0.55 -6.26 -0.32 1.15e-9 Colorectal cancer; LIHC cis rs2991971 0.933 rs2356553 chr1:46009313 G/C cg15605315 chr1:45957053 TESK2 0.45 6.01 0.31 4.73e-9 High light scatter reticulocyte count; LIHC cis rs7707921 0.881 rs324914 chr5:81389950 C/T cg15871215 chr5:81402204 ATG10 0.59 5.83 0.3 1.27e-8 Breast cancer; LIHC cis rs12540874 0.663 rs1451371 chr7:50553051 T/C cg18232548 chr7:50535776 DDC -0.39 -5.96 -0.31 6.34e-9 Systemic sclerosis; LIHC cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.41 0.52 9.38e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7520050 1.000 rs12143096 chr1:46469763 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.0 0.31 4.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg16145915 chr7:1198662 ZFAND2A -0.41 -11.08 -0.51 1.41e-24 Longevity;Endometriosis; LIHC cis rs17001868 0.568 rs9611314 chr22:40735798 C/G cg07138101 chr22:40742427 ADSL 0.54 6.33 0.32 7.84e-10 Mammographic density (dense area); LIHC cis rs1862618 0.620 rs189695 chr5:56225769 T/C cg24531977 chr5:56204891 C5orf35 -0.54 -7.83 -0.39 6.27e-14 Initial pursuit acceleration; LIHC cis rs7927771 0.832 rs935914 chr11:47387599 C/T cg20307385 chr11:47447363 PSMC3 0.44 5.9 0.3 8.82e-9 Subjective well-being; LIHC cis rs7100689 0.622 rs2342816 chr10:82086546 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg19500275 chr17:80737654 TBCD 0.5 7.34 0.37 1.6e-12 Glycated hemoglobin levels; LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg13012494 chr21:47604986 C21orf56 -0.39 -6.16 -0.32 2.06e-9 Testicular germ cell tumor; LIHC cis rs7944584 0.632 rs749067 chr11:47318157 T/C cg20307385 chr11:47447363 PSMC3 0.58 6.41 0.33 4.92e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2921073 0.605 rs2976933 chr8:8254875 A/G cg06636001 chr8:8085503 FLJ10661 0.64 9.22 0.45 3.01e-18 Parkinson's disease; LIHC cis rs12477438 0.765 rs2309454 chr2:99595418 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.55 -0.38 3.87e-13 Chronic sinus infection; LIHC cis rs12701220 0.655 rs10215292 chr7:1135263 A/G cg04025307 chr7:1156635 C7orf50 0.55 7.33 0.37 1.68e-12 Bronchopulmonary dysplasia; LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg04013166 chr16:89971882 TCF25 0.6 7.9 0.39 3.72e-14 Skin colour saturation; LIHC trans rs1814175 0.817 rs10769617 chr11:49810421 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.53 -0.79 1.77e-73 Height; LIHC cis rs7772486 0.875 rs10872583 chr6:146396699 G/T cg23711669 chr6:146136114 FBXO30 -0.58 -9.79 -0.47 4.03e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 0.955 rs1129200 chr3:40532257 T/C cg00091569 chr3:40428383 ENTPD3 0.35 5.73 0.3 2.18e-8 Renal cell carcinoma; LIHC cis rs9486715 0.929 rs7775721 chr6:97056979 C/T cg18709589 chr6:96969512 KIAA0776 -0.39 -6.74 -0.34 6.71e-11 Headache; LIHC cis rs208520 0.690 rs12213581 chr6:66735818 T/C cg07460842 chr6:66804631 NA 0.79 9.18 0.44 4.09e-18 Exhaled nitric oxide output; LIHC cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg22105103 chr4:187893119 NA 0.34 8.48 0.42 7.07e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.895 rs6460278 chr7:65662736 T/C cg18876405 chr7:65276391 NA -0.35 -6.39 -0.33 5.29e-10 Aortic root size; LIHC cis rs6088590 1.000 rs11698996 chr20:33449739 C/G cg24642439 chr20:33292090 TP53INP2 0.78 10.13 0.48 2.79e-21 Coronary artery disease; LIHC cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs739401 0.611 rs10833048 chr11:3020040 A/G cg20651018 chr11:3035856 CARS -0.35 -5.79 -0.3 1.63e-8 Longevity; LIHC cis rs8114671 0.839 rs6142290 chr20:33654672 A/C cg07148914 chr20:33460835 GGT7 -0.55 -8.29 -0.41 2.63e-15 Height; LIHC cis rs7100689 0.556 rs10788541 chr10:82016530 T/G cg00277334 chr10:82204260 NA -0.49 -6.02 -0.31 4.4e-9 Post bronchodilator FEV1; LIHC cis rs10504229 0.593 rs4738567 chr8:57997033 A/C cg02290350 chr8:58132656 NA 0.32 6.97 0.35 1.63e-11 Developmental language disorder (linguistic errors); LIHC cis rs10242455 0.702 rs45461000 chr7:99052710 A/G cg18809830 chr7:99032528 PTCD1 -0.83 -6.45 -0.33 3.76e-10 Blood metabolite levels; LIHC cis rs7312933 0.558 rs11181501 chr12:42822671 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 8.01 0.4 1.76e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1580019 0.587 rs7806113 chr7:32553084 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.17 0.32 1.88e-9 Cognitive ability; LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg19635926 chr16:89946313 TCF25 0.57 7.56 0.38 3.82e-13 Skin colour saturation; LIHC cis rs17331151 0.573 rs11718060 chr3:52875546 G/A cg04865290 chr3:52927548 TMEM110 -0.48 -7.04 -0.36 1.03e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs360798 0.532 rs12713468 chr2:62983213 G/A cg17519650 chr2:63277830 OTX1 -0.54 -8.38 -0.41 1.44e-15 Coronary artery disease; LIHC cis rs2404602 0.735 rs4886493 chr15:76679026 A/G cg03037974 chr15:76606532 NA -0.66 -11.75 -0.54 5.35e-27 Blood metabolite levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20750930 chr12:133159939 FBRSL1 0.43 6.35 0.32 6.75e-10 Longevity; LIHC cis rs9952991 0.941 rs888270 chr18:12774894 G/A cg23598886 chr18:12777645 NA -0.46 -6.16 -0.32 2.03e-9 Inflammatory skin disease; LIHC cis rs9814567 0.896 rs4245907 chr3:134347876 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.59 -9.88 -0.47 2.04e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9649213 0.593 rs2107716 chr7:97944744 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.84 -0.3 1.2e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs739401 0.527 rs418832 chr11:3072236 C/T cg25174290 chr11:3078921 CARS 0.67 10.27 0.49 9.62e-22 Longevity; LIHC cis rs748404 0.660 rs548704 chr15:43791706 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.39 0.37 1.15e-12 Lung cancer; LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs2072499 0.833 rs2758605 chr1:156200445 G/C cg24450063 chr1:156163899 SLC25A44 0.72 12.48 0.56 1.02e-29 Testicular germ cell tumor; LIHC cis rs3859192 0.561 rs12451547 chr17:38181168 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.89 0.65 5.71e-43 White blood cell count; LIHC cis rs12477438 0.501 rs1133977 chr2:99741984 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.61 -11.32 -0.52 1.97e-25 Chronic sinus infection; LIHC cis rs11718455 0.960 rs11921942 chr3:44007957 T/C cg08738300 chr3:44038990 NA 0.52 8.97 0.44 1.98e-17 Coronary artery disease; LIHC cis rs1144333 1.000 rs5745392 chr1:76306809 C/T cg22875332 chr1:76189707 ACADM 0.44 7.07 0.36 8.86e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs2070488 1.000 rs7373805 chr3:38455439 C/T cg24069376 chr3:38537580 EXOG 0.43 7.9 0.39 3.93e-14 Electrocardiographic conduction measures; LIHC cis rs1707322 0.716 rs28375469 chr1:46195375 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1577917 0.681 rs4707211 chr6:86232710 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.44 8.18 0.4 5.65e-15 Response to antipsychotic treatment; LIHC cis rs1816752 0.935 rs4770676 chr13:25003883 A/G cg22771759 chr13:24902376 NA 0.33 6.75 0.34 6.21e-11 Obesity-related traits; LIHC cis rs9513627 0.588 rs9585073 chr13:100128516 A/G cg25919922 chr13:100150906 NA -0.77 -6.89 -0.35 2.74e-11 Obesity-related traits; LIHC cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.74 -8.89 -0.43 3.59e-17 Gut microbiome composition (summer); LIHC cis rs9790314 0.934 rs462413 chr3:161101587 T/C cg03342759 chr3:160939853 NMD3 -0.72 -8.47 -0.42 7.3e-16 Morning vs. evening chronotype; LIHC cis rs317689 0.690 rs317646 chr12:69657145 A/G cg19645103 chr12:69753606 YEATS4 0.44 5.98 0.31 5.6e-9 Response to diuretic therapy; LIHC cis rs1862618 0.641 rs170733 chr5:56249251 A/G cg12311346 chr5:56204834 C5orf35 0.44 5.83 0.3 1.3e-8 Initial pursuit acceleration; LIHC trans rs3780486 0.846 rs10971420 chr9:33125000 T/C cg20290983 chr6:43655470 MRPS18A 1.16 30.42 0.85 2.6e-99 IgG glycosylation; LIHC cis rs9733 0.519 rs1336899 chr1:150678910 T/C cg18016565 chr1:150552671 MCL1 0.59 11.39 0.52 1.06e-25 Tonsillectomy; LIHC cis rs3741404 0.825 rs11603384 chr11:63949095 G/A cg24431193 chr11:63883947 FLRT1;MACROD1 -0.41 -6.2 -0.32 1.58e-9 Platelet count; LIHC cis rs2108225 0.714 rs929394 chr7:107437252 C/T cg18560240 chr7:107437656 SLC26A3 -0.54 -8.74 -0.43 1.03e-16 Ulcerative colitis; LIHC cis rs16912059 0.661 rs16912302 chr11:24267144 A/G ch.11.24196551F chr11:24239977 NA 0.73 6.09 0.31 3.04e-9 Thrombin-antithrombin complex levels in ischemic stroke; LIHC cis rs72615157 0.664 rs6953580 chr7:99825275 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.55 6.05 0.31 3.89e-9 Lung function (FEV1/FVC); LIHC cis rs1552244 0.882 rs28366039 chr3:10028988 C/A cg13047869 chr3:10149882 C3orf24 0.43 5.81 0.3 1.43e-8 Alzheimer's disease; LIHC cis rs16828019 0.852 rs35190461 chr1:41543135 T/C cg03962019 chr1:41807865 NA 0.5 7.32 0.37 1.83e-12 Intelligence (multi-trait analysis); LIHC cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg12437481 chr16:420112 MRPL28 -0.63 -9.05 -0.44 1.11e-17 Bone mineral density (spine);Bone mineral density; LIHC cis rs2842992 0.915 rs2758321 chr6:160071611 C/G cg11366901 chr6:160182831 ACAT2 0.91 14.48 0.62 2.15e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs6450176 0.909 rs3776712 chr5:53304179 T/C ch.5.1024479R chr5:53302184 ARL15 -0.81 -14.64 -0.62 4.92e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs2727020 0.729 rs2299650 chr11:49174007 A/C cg03929089 chr4:120376271 NA -0.78 -13.92 -0.6 3.4000000000000003e-35 Coronary artery disease; LIHC cis rs10088262 0.629 rs12541177 chr8:124800273 G/T cg20713898 chr8:124780851 FAM91A1 -0.54 -7.26 -0.37 2.61e-12 Pancreatic cancer; LIHC cis rs2439831 0.867 rs689616 chr15:43761901 C/T cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.32e-9 Lung cancer in ever smokers; LIHC cis rs4689592 0.503 rs2292461 chr4:7058473 C/T cg06697600 chr4:7070879 GRPEL1 -0.61 -9.61 -0.46 1.63e-19 Monocyte percentage of white cells; LIHC cis rs3749237 1.000 rs2307021 chr3:49765483 C/G cg03060546 chr3:49711283 APEH 0.38 5.94 0.31 6.96e-9 Resting heart rate; LIHC cis rs78545713 0.892 rs113432940 chr6:26256324 T/A cg16070018 chr6:26224392 HIST1H3E 0.57 6.63 0.34 1.28e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs2115630 0.691 rs8040066 chr15:85176465 G/C cg12501888 chr15:85177176 SCAND2 -0.49 -7.64 -0.38 2.21e-13 P wave terminal force; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02664216 chr12:19592651 AEBP2 0.45 6.23 0.32 1.34e-9 Pancreatic cancer; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.36 0.61 6.46e-37 Prudent dietary pattern; LIHC cis rs7395581 0.959 rs7129661 chr11:47268550 T/G cg26139080 chr11:47293733 MADD -0.49 -8.28 -0.41 2.71e-15 HDL cholesterol; LIHC cis rs1008375 1.000 rs10939742 chr4:17659936 G/T cg02297831 chr4:17616191 MED28 0.51 7.99 0.4 2.16e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs881375 0.933 rs4837799 chr9:123668326 T/C cg14580859 chr9:123691850 NA 0.39 6.79 0.34 4.96e-11 Rheumatoid arthritis; LIHC cis rs2629540 0.824 rs1552345 chr10:126477406 A/G cg08799069 chr10:126477246 METTL10 -0.53 -8.72 -0.43 1.27e-16 Cocaine dependence; LIHC trans rs877282 0.583 rs10904562 chr10:819058 T/C cg22713356 chr15:30763199 NA 0.86 7.22 0.36 3.31e-12 Uric acid levels; LIHC cis rs12477438 0.798 rs6705821 chr2:99602832 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.58 -0.53 2.12e-26 Chronic sinus infection; LIHC cis rs4917833 0.700 rs7067691 chr10:100221081 T/C cg19043522 chr10:100227446 HPSE2 0.4 5.77 0.3 1.8e-8 Pediatric bone mineral density (femoral neck); LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg22903471 chr2:27725779 GCKR -0.51 -8.9 -0.43 3.28e-17 Total body bone mineral density; LIHC trans rs4843747 0.671 rs8062855 chr16:88106941 T/C cg26811252 chr16:29126840 RRN3P2 0.42 6.8 0.35 4.59e-11 Menopause (age at onset); LIHC cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg11644478 chr21:40555479 PSMG1 0.81 10.09 0.48 4.05e-21 Cognitive function; LIHC cis rs763121 0.853 rs5750649 chr22:39036769 T/C cg14440974 chr22:39074834 NA -0.35 -5.8 -0.3 1.51e-8 Menopause (age at onset); LIHC cis rs4660306 0.614 rs12032658 chr1:45923851 C/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.66 6.8 0.35 4.57e-11 Homocysteine levels; LIHC trans rs7504990 0.722 rs34899419 chr18:50359614 G/C cg08535148 chr4:26321143 RBPJ 0.54 6.73 0.34 7.03e-11 Gallbladder cancer; LIHC cis rs7078219 0.505 rs1548964 chr10:101289653 C/G cg06854084 chr10:101292507 NKX2-3 0.32 5.75 0.3 1.97e-8 Dental caries; LIHC trans rs1005277 0.579 rs2749612 chr10:38488610 G/A cg27523141 chr10:43048294 ZNF37B 0.38 6.34 0.32 7.24e-10 Extrinsic epigenetic age acceleration; LIHC cis rs116095464 0.558 rs62344345 chr5:257420 C/T cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC trans rs1814175 0.817 rs10769598 chr11:49669326 C/G cg03929089 chr4:120376271 NA -0.88 -17.76 -0.69 1.76e-50 Height; LIHC cis rs317689 0.718 rs645026 chr12:69757931 G/A cg14784868 chr12:69753453 YEATS4 0.67 10.1 0.48 3.78e-21 Response to diuretic therapy; LIHC cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg14646974 chr10:38645378 HSD17B7P2 -0.42 -5.92 -0.31 7.67e-9 Extrinsic epigenetic age acceleration; LIHC trans rs8073060 0.516 rs2376177 chr17:33938089 T/G cg19694781 chr19:47549865 TMEM160 -1.25 -13.43 -0.59 2.45e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18441082 chr5:16466057 ZNF622 0.46 6.65 0.34 1.16e-10 Lung function (FEV1/FVC); LIHC cis rs7572733 0.534 rs1607374 chr2:198800440 A/G cg10820045 chr2:198174542 NA 0.46 6.82 0.35 4.02e-11 Dermatomyositis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17947461 chr1:87797169 LMO4 0.45 6.52 0.33 2.49e-10 Lung function (FEV1/FVC); LIHC cis rs8067354 0.872 rs7224006 chr17:57896338 C/T cg02344993 chr17:57696989 CLTC -0.57 -9.29 -0.45 1.78e-18 Hemoglobin concentration; LIHC cis rs12472274 0.941 rs2880131 chr2:239089151 A/C cg17459225 chr2:239074497 NA 0.78 12.96 0.57 1.57e-31 Phospholipid levels (plasma); LIHC cis rs6061231 0.793 rs6061512 chr20:60976929 G/A cg06026331 chr20:60912101 LAMA5 0.48 6.44 0.33 4.05e-10 Colorectal cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06552368 chr11:118972898 DPAGT1 -0.52 -6.45 -0.33 3.88e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.73 0.34 7.2e-11 Bipolar disorder; LIHC trans rs2243480 1.000 rs2465120 chr7:65620974 C/G cg10756647 chr7:56101905 PSPH 1.1 13.4 0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs4423214 1.000 rs4944062 chr11:71187294 G/T cg24826892 chr11:71159390 DHCR7 0.49 6.27 0.32 1.08e-9 Vitamin D levels; LIHC cis rs13217239 0.646 rs4403259 chr6:26997617 C/T cg18867708 chr6:26865862 GUSBL1 0.54 8.24 0.41 3.74e-15 Schizophrenia; LIHC cis rs2439831 0.867 rs2447208 chr15:43933895 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.66 9.58 0.46 2.02e-19 Lung cancer in ever smokers; LIHC cis rs16958440 0.609 rs75911383 chr18:44716011 C/T cg17192377 chr18:44677553 HDHD2 0.91 8.68 0.42 1.64e-16 Sitting height ratio; LIHC cis rs3812831 0.695 rs423237 chr13:114930955 C/T cg06611532 chr13:114900021 NA 0.43 7.81 0.39 6.88e-14 Schizophrenia; LIHC cis rs738322 0.600 rs7286105 chr22:38557821 A/G cg25457927 chr22:38595422 NA -0.36 -8.56 -0.42 3.75e-16 Cutaneous nevi; LIHC cis rs7584330 0.666 rs60671275 chr2:238374318 C/A cg14458575 chr2:238380390 NA 0.54 7.72 0.39 1.25e-13 Prostate cancer; LIHC cis rs1003719 0.762 rs3787786 chr21:38463436 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC trans rs11098499 0.708 rs11732686 chr4:120252330 C/A cg25214090 chr10:38739885 LOC399744 0.51 8.25 0.41 3.48e-15 Corneal astigmatism; LIHC cis rs6714710 0.580 rs1838797 chr2:98454572 G/C cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs7927592 0.763 rs10896340 chr11:68312645 A/G cg20283391 chr11:68216788 NA 0.38 6.12 0.31 2.51e-9 Total body bone mineral density; LIHC cis rs981946 0.965 rs9503565 chr6:3369031 A/G cg18842474 chr6:3356384 SLC22A23 0.38 5.92 0.31 7.7e-9 Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN); LIHC cis rs11098499 0.866 rs11098506 chr4:120284971 A/G cg09307838 chr4:120376055 NA 0.64 9.7 0.46 8.08e-20 Corneal astigmatism; LIHC cis rs4819052 0.851 rs2236443 chr21:46678174 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.77 0.39 9.22e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7762018 0.891 rs73242950 chr6:170144737 C/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.77 0.34 5.71e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs12493885 0.725 rs73158427 chr3:153721493 T/A cg10247383 chr3:153839028 SGEF 0.65 6.12 0.31 2.58e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs986417 0.901 rs1010052 chr14:61003071 G/A cg27398547 chr14:60952738 C14orf39 0.83 9.47 0.46 4.66e-19 Gut microbiota (bacterial taxa); LIHC cis rs4975709 0.589 rs1684967 chr5:1863055 G/C cg15595755 chr5:1867978 NA 0.4 8.12 0.4 8.47e-15 Cardiovascular disease risk factors; LIHC cis rs1816752 1.000 rs7988810 chr13:25019096 T/C cg02811702 chr13:24901961 NA 0.25 6.23 0.32 1.35e-9 Obesity-related traits; LIHC cis rs9513627 1.000 rs7338761 chr13:100119731 A/G cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs4803468 1.000 rs10417311 chr19:41902038 G/A cg09537434 chr19:41945824 ATP5SL -1.0 -20.91 -0.75 3.87e-63 Height; LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg12064134 chr16:90016061 DEF8 -0.46 -6.11 -0.31 2.78e-9 Skin colour saturation; LIHC cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg19318889 chr4:1322082 MAEA 0.46 6.48 0.33 3.24e-10 Obesity-related traits; LIHC trans rs11098499 0.874 rs17839089 chr4:120111069 A/G cg25214090 chr10:38739885 LOC399744 0.45 7.18 0.36 4.39e-12 Corneal astigmatism; LIHC cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs7662987 0.517 rs1154405 chr4:100008750 G/A cg13256891 chr4:100009986 ADH5 0.56 5.77 0.3 1.81e-8 Smoking initiation; LIHC cis rs7000551 0.751 rs2461482 chr8:22382898 C/T cg13512537 chr8:22265999 SLC39A14 -0.35 -5.94 -0.31 6.86e-9 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2370759 1.000 rs11599522 chr10:32568434 G/C cg01819863 chr10:32635814 EPC1 1.12 16.62 0.67 6.91e-46 Sexual dysfunction (female); LIHC cis rs2197308 0.659 rs11181327 chr12:37903171 C/T cg26384229 chr12:38710491 ALG10B -0.47 -6.64 -0.34 1.23e-10 Morning vs. evening chronotype; LIHC trans rs12780046 0.656 rs1970536 chr10:100823868 T/C cg05980083 chr9:112191166 PTPN3 -0.47 -6.27 -0.32 1.09e-9 Non-glioblastoma glioma; LIHC cis rs2607426 0.681 rs17726258 chr19:41287605 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.5 -6.5 -0.33 2.77e-10 Blood protein levels; LIHC cis rs7568498 0.564 rs9287807 chr2:161915361 T/C cg22496339 chr2:162101262 NA -0.52 -7.07 -0.36 8.57e-12 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC cis rs4407350 1.000 rs4373014 chr22:44922424 C/T cg11695653 chr22:44894386 LDOC1L -0.37 -6.05 -0.31 3.78e-9 Intelligence (multi-trait analysis); LIHC cis rs11630290 0.592 rs11071769 chr15:64156842 G/C cg12036633 chr15:63758958 NA 0.62 6.62 0.34 1.43e-10 Iris characteristics; LIHC trans rs7618501 1.000 rs1491986 chr3:49739086 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.07 -0.63 1e-39 Intelligence (multi-trait analysis); LIHC cis rs7552404 0.765 rs211717 chr1:76106969 G/A cg10523679 chr1:76189770 ACADM -0.66 -9.21 -0.45 3.36e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1005277 0.557 rs2983338 chr10:38550734 C/T cg25427524 chr10:38739819 LOC399744 -0.75 -15.23 -0.64 2.43e-40 Extrinsic epigenetic age acceleration; LIHC cis rs10752881 1.000 rs10797800 chr1:182969828 C/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.36 0.49 4.72e-22 Colorectal cancer; LIHC cis rs422249 0.593 rs174613 chr11:61628492 G/A cg27386326 chr11:61587980 NA 0.33 5.82 0.3 1.36e-8 Trans fatty acid levels; LIHC cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg15691649 chr6:25882328 NA -0.51 -7.39 -0.37 1.14e-12 Blood metabolite levels; LIHC cis rs910316 0.737 rs175499 chr14:75535927 G/A cg11812906 chr14:75593930 NEK9 -0.75 -14.25 -0.61 1.64e-36 Height; LIHC cis rs7592578 0.882 rs2192010 chr2:191462133 C/T cg27211696 chr2:191398769 TMEM194B -0.6 -7.62 -0.38 2.54e-13 Diastolic blood pressure; LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg00106254 chr7:1943704 MAD1L1 0.45 7.66 0.38 1.91e-13 Bipolar disorder and schizophrenia; LIHC cis rs35110281 0.633 rs4819292 chr21:45125223 A/G cg21573476 chr21:45109991 RRP1B -0.51 -9.54 -0.46 2.69e-19 Mean corpuscular volume; LIHC cis rs34779708 0.966 rs4934536 chr10:35441169 A/G cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs8017423 0.967 rs2151748 chr14:90694897 G/C cg14092571 chr14:90743983 NA -0.38 -6.05 -0.31 3.86e-9 Mortality in heart failure; LIHC cis rs75908454 1.000 rs74908176 chr6:169936353 G/A cg19338460 chr6:170058176 WDR27 -0.83 -7.75 -0.39 1.04e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs4423214 1.000 rs11606612 chr11:71164047 C/A cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs7659604 0.605 rs1396080 chr4:122740454 T/G cg19748678 chr4:122722346 EXOSC9 0.53 8.85 0.43 4.92e-17 Type 2 diabetes; LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg00091569 chr3:40428383 ENTPD3 0.4 6.83 0.35 4.01e-11 Renal cell carcinoma; LIHC cis rs1348850 0.514 rs4893974 chr2:178497026 A/G cg27490568 chr2:178487706 NA 0.85 10.68 0.5 3.59e-23 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2115536 1.000 rs7163338 chr15:80198408 C/G cg00225070 chr15:80189496 MTHFS 0.53 8.8 0.43 7.06e-17 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs1385374 0.920 rs61946175 chr12:129273021 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.66 0.38 1.97e-13 Systemic lupus erythematosus; LIHC trans rs61931739 0.534 rs11052991 chr12:34059018 G/T cg26384229 chr12:38710491 ALG10B -0.47 -6.64 -0.34 1.27e-10 Morning vs. evening chronotype; LIHC cis rs918629 0.567 rs10069748 chr5:95241222 C/T cg10483112 chr5:95245456 ELL2 0.38 7.03 0.36 1.16e-11 IgG glycosylation; LIHC cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg03806693 chr22:41940476 POLR3H -1.08 -12.5 -0.56 8.97e-30 Vitiligo; LIHC cis rs4727027 0.933 rs4725800 chr7:148862516 C/G cg23583168 chr7:148888333 NA -0.72 -10.28 -0.49 9.19e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs1008375 0.966 rs3733576 chr4:17586703 T/C cg16339924 chr4:17578868 LAP3 0.59 7.59 0.38 3e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9914988 0.943 rs4795459 chr17:27113726 G/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7309 0.935 rs10930013 chr2:162070325 G/A cg16506815 chr2:162101123 NA 0.57 9.86 0.47 2.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs1401999 0.510 rs17817736 chr3:183720313 A/T cg01324343 chr3:183735012 ABCC5 -0.4 -6.47 -0.33 3.43e-10 Anterior chamber depth; LIHC cis rs2274273 1.000 rs3825613 chr14:55593172 A/C cg01864836 chr14:55583639 NA -0.36 -6.15 -0.32 2.14e-9 Protein biomarker; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg01737828 chr15:75230659 COX5A -0.48 -6.18 -0.32 1.82e-9 Facial morphology (factor 20); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17040068 chr7:102715209 ARMC10;FBXL13 0.45 6.59 0.34 1.62e-10 Pancreatic cancer; LIHC cis rs2629540 0.882 rs10901813 chr10:126429875 G/A cg08799069 chr10:126477246 METTL10 -0.5 -7.81 -0.39 7.2e-14 Cocaine dependence; LIHC cis rs35110281 0.782 rs9981790 chr21:45045052 G/C cg04455712 chr21:45112962 RRP1B 0.45 7.84 0.39 5.68e-14 Mean corpuscular volume; LIHC cis rs2404602 0.716 rs2404736 chr15:76875943 T/C cg03037974 chr15:76606532 NA 0.74 14.43 0.62 3.4e-37 Blood metabolite levels; LIHC cis rs1982963 0.950 rs2645749 chr14:52502795 C/A cg10843707 chr14:52510701 NID2 -0.43 -7.18 -0.36 4.27e-12 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17125944 0.505 rs2295826 chr14:53174923 C/T cg13660082 chr14:53194042 PSMC6 0.41 7.13 0.36 6.12e-12 Alzheimer's disease (late onset); LIHC cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg03264133 chr6:25882463 NA -0.64 -9.09 -0.44 8.02e-18 Blood metabolite levels; LIHC cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg27170947 chr2:26402098 FAM59B 0.65 8.36 0.41 1.57e-15 Gut microbiome composition (summer); LIHC cis rs7116495 0.609 rs2735787 chr11:71717873 T/C cg26138937 chr11:71823887 C11orf51 -1.32 -10.9 -0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs35110281 0.641 rs4818858 chr21:45083097 C/T cg01579765 chr21:45077557 HSF2BP 0.34 6.21 0.32 1.57e-9 Mean corpuscular volume; LIHC cis rs2404602 0.692 rs35195096 chr15:76938447 C/T cg03037974 chr15:76606532 NA 0.74 14.44 0.62 3.1e-37 Blood metabolite levels; LIHC cis rs2235649 0.592 rs7197113 chr16:1969483 G/A cg00564555 chr16:1970112 NA -0.28 -5.93 -0.31 7.45e-9 Blood metabolite levels; LIHC cis rs7927592 0.913 rs6591346 chr11:68384618 T/A cg16797656 chr11:68205561 LRP5 0.52 8.27 0.41 2.91e-15 Total body bone mineral density; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.96e-16 Prudent dietary pattern; LIHC cis rs7726839 0.561 rs72703044 chr5:579737 G/A cg09021430 chr5:549028 NA -0.41 -8.63 -0.42 2.28e-16 Obesity-related traits; LIHC cis rs4665809 0.887 rs6546716 chr2:26263836 A/G cg27170947 chr2:26402098 FAM59B -0.68 -8.33 -0.41 1.97e-15 Gut microbiome composition (summer); LIHC cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg27572855 chr1:25598939 RHD 0.38 7.83 0.39 6.01e-14 Erythrocyte sedimentation rate; LIHC cis rs4699052 1.000 rs4699055 chr4:104154500 T/C cg16532752 chr4:104119610 CENPE -0.42 -6.63 -0.34 1.3100000000000001e-10 Testicular germ cell tumor; LIHC cis rs1707322 1.000 rs785470 chr1:46519622 C/A cg03146154 chr1:46216737 IPP -0.44 -7.16 -0.36 4.84e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2439831 0.681 rs28653441 chr15:43677262 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.73 10.74 0.5 2.16e-23 Lung cancer in ever smokers; LIHC cis rs1215050 0.791 rs260902 chr4:98764694 G/A cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2204008 0.745 rs12146863 chr12:38502346 G/A cg13010199 chr12:38710504 ALG10B 0.45 6.04 0.31 3.94e-9 Bladder cancer; LIHC cis rs2467099 0.786 rs1463486 chr17:73943942 G/A cg08125733 chr17:73851984 WBP2 0.46 5.78 0.3 1.69e-8 Systolic blood pressure; LIHC cis rs17428076 0.793 rs7584258 chr2:172659836 A/G cg13550731 chr2:172543902 DYNC1I2 0.39 6.23 0.32 1.4e-9 Myopia; LIHC cis rs10028773 0.700 rs7690338 chr4:120256468 C/G cg09307838 chr4:120376055 NA 0.7 11.05 0.51 1.72e-24 Educational attainment; LIHC cis rs6782228 0.606 rs2712405 chr3:128332082 T/C cg16766828 chr3:128327626 NA -0.41 -6.42 -0.33 4.62e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs4076764 0.958 rs10917748 chr1:163400377 T/C cg24596788 chr1:163392923 NA -0.25 -7.77 -0.39 9.52e-14 Motion sickness; LIHC cis rs9916302 0.904 rs7503069 chr17:37697128 C/G cg00129232 chr17:37814104 STARD3 -0.42 -6.68 -0.34 9.86e-11 Glomerular filtration rate (creatinine); LIHC cis rs7044106 0.791 rs747819 chr9:123488441 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.77 12.65 0.56 2.36e-30 Hip circumference adjusted for BMI; LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg11494091 chr17:61959527 GH2 0.44 8.07 0.4 1.17e-14 Prudent dietary pattern; LIHC cis rs2404602 0.735 rs2957614 chr15:76696635 C/T cg03037974 chr15:76606532 NA 0.66 11.99 0.54 7.01e-28 Blood metabolite levels; LIHC cis rs3020736 0.500 rs11090076 chr22:42514190 T/C cg15557168 chr22:42548783 NA 0.43 6.75 0.34 6.44e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs722599 0.748 rs2300599 chr14:75359441 A/G cg08847533 chr14:75593920 NEK9 -0.58 -9.46 -0.46 5.32e-19 IgG glycosylation; LIHC cis rs2412488 0.893 rs11947256 chr4:54289362 G/A cg22241045 chr4:54363911 LNX1 -0.43 -6.97 -0.35 1.68e-11 DNA methylation (variation); LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg07157834 chr1:205819609 PM20D1 0.67 10.06 0.48 4.98e-21 Menarche (age at onset); LIHC cis rs769267 0.896 rs2074298 chr19:19377716 C/G cg15052019 chr19:19431593 KIAA0892;SF4 0.45 6.19 0.32 1.74e-9 Tonsillectomy; LIHC cis rs589448 1.000 rs589448 chr12:69752200 A/G cg14784868 chr12:69753453 YEATS4 1.0 23.05 0.78 1.35e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs6138458 0.546 rs6050118 chr20:24891895 C/T cg26195577 chr20:24973756 C20orf3 -0.86 -8.68 -0.42 1.67e-16 Blood protein levels; LIHC cis rs600806 0.854 rs367586 chr1:109850122 C/A cg02415029 chr1:110025642 ATXN7L2 -0.49 -6.03 -0.31 4.24e-9 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.656 rs2173582 chr12:122824694 A/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.39 -0.37 1.14e-12 Body mass index; LIHC cis rs875971 0.825 rs7384021 chr7:66077904 A/G cg18252515 chr7:66147081 NA 0.45 6.56 0.33 1.97e-10 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08188400 chr19:7969347 MAP2K7 0.46 6.98 0.35 1.55e-11 Pancreatic cancer; LIHC cis rs651907 0.557 rs11710533 chr3:101351472 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.59 0.5 7.61e-23 Colorectal cancer; LIHC cis rs13343954 0.518 rs8106293 chr19:33536376 C/T cg27124370 chr19:33622961 WDR88 0.54 8.05 0.4 1.35e-14 Colorectal cancer; LIHC cis rs3791406 0.500 rs3791414 chr2:240032214 T/C cg14550559 chr2:240039617 HDAC4 -0.67 -8.38 -0.41 1.36e-15 Skin aging (microtopography measurement); LIHC trans rs10506458 0.834 rs58821476 chr12:63389425 T/C cg22491629 chr6:157744540 C6orf35 -0.61 -10.92 -0.51 4.95e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs1348850 0.846 rs4893962 chr2:178421106 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.77 11.44 0.53 7.25e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7666738 0.687 rs6830176 chr4:99093955 G/C cg05340658 chr4:99064831 C4orf37 0.65 11.57 0.53 2.29e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2120019 0.938 rs3850093 chr15:75318482 A/G cg11632617 chr15:75315747 PPCDC 0.47 6.66 0.34 1.1e-10 Blood trace element (Zn levels); LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs7116495 1.000 rs55972015 chr11:71642576 C/G cg26138937 chr11:71823887 C11orf51 -0.76 -7.75 -0.39 1.09e-13 Severe influenza A (H1N1) infection; LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg22963979 chr7:1858916 MAD1L1 0.39 6.23 0.32 1.37e-9 Bipolar disorder and schizophrenia; LIHC cis rs875971 1.000 rs778710 chr7:65854834 T/C cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs6840360 0.593 rs28602726 chr4:152499788 T/C cg22705602 chr4:152727874 NA -0.33 -6.36 -0.33 6.39e-10 Intelligence (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg02477380 chr7:156931759 UBE3C -0.4 -6.31 -0.32 8.85e-10 Calcium levels; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg04267008 chr7:1944627 MAD1L1 -0.59 -9.03 -0.44 1.24e-17 Bipolar disorder and schizophrenia; LIHC cis rs9388451 0.839 rs9321054 chr6:126079968 A/G cg05901451 chr6:126070800 HEY2 0.76 18.08 0.7 9.06e-52 Brugada syndrome; LIHC cis rs734999 0.545 rs10797441 chr1:2551660 T/G cg18854424 chr1:2615690 NA 0.33 7.3 0.37 2.01e-12 Ulcerative colitis; LIHC cis rs801193 1.000 rs2707836 chr7:66160435 A/C cg11764359 chr7:65958608 NA 0.71 10.55 0.5 1.02e-22 Aortic root size; LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg07677032 chr17:61819896 STRADA 0.43 6.25 0.32 1.23e-9 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs12765878 1.000 rs11191847 chr10:105650626 G/C cg11005552 chr10:105648138 OBFC1 0.39 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs796364 0.616 rs769955 chr2:200692595 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.57 6.29 0.32 9.6e-10 Schizophrenia; LIHC cis rs765787 0.530 rs2899381 chr15:45529630 C/T cg25801113 chr15:45476975 SHF 0.37 6.36 0.33 6.62e-10 Uric acid levels; LIHC cis rs3008870 1.000 rs2755240 chr1:67477339 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.93 15.73 0.65 2.57e-42 Lymphocyte percentage of white cells; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg04857149 chr18:24237060 NA -0.46 -6.05 -0.31 3.74e-9 Electroencephalogram traits; LIHC cis rs8067354 0.645 rs11079389 chr17:57887952 G/A cg13753209 chr17:57696993 CLTC 0.77 12.28 0.55 6.02e-29 Hemoglobin concentration; LIHC cis rs2832191 0.791 rs2832178 chr21:30479858 T/G cg24692254 chr21:30365293 RNF160 -0.7 -12.84 -0.57 4.5e-31 Dental caries; LIHC cis rs2732480 0.500 rs2450989 chr12:48653408 A/G cg21466736 chr12:48725269 NA 0.69 10.86 0.51 8.09e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs6500602 0.727 rs4786509 chr16:4568769 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.49 -7.43 -0.37 8.69e-13 Schizophrenia; LIHC cis rs7756236 0.521 rs9462209 chr6:36628042 T/G cg08179530 chr6:36648295 CDKN1A 0.41 6.07 0.31 3.41e-9 QRS duration; LIHC cis rs1401999 0.966 rs2139560 chr3:183653869 A/G cg05044414 chr3:183734942 ABCC5 0.34 5.97 0.31 6.01e-9 Anterior chamber depth; LIHC cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg21724239 chr8:58056113 NA 0.46 6.23 0.32 1.36e-9 Developmental language disorder (linguistic errors); LIHC cis rs743757 1.000 rs2236965 chr3:50453456 T/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.15 0.32 2.13e-9 Diastolic blood pressure; LIHC cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg19774624 chr17:42201019 HDAC5 -0.8 -12.45 -0.56 1.35e-29 Total body bone mineral density; LIHC trans rs1814175 0.935 rs28586931 chr11:49693872 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -21.62 -0.76 6.02e-66 Height; LIHC cis rs2857078 0.720 rs9906669 chr17:42305706 A/G cg19774624 chr17:42201019 HDAC5 -0.56 -7.86 -0.39 5.08e-14 Red cell distribution width;Reticulocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22627950 chr7:44622302 TMED4 0.47 6.58 0.34 1.79e-10 Pancreatic cancer; LIHC cis rs7107174 0.892 rs7115850 chr11:78045071 C/G cg02023728 chr11:77925099 USP35 0.43 8.41 0.41 1.12e-15 Testicular germ cell tumor; LIHC trans rs7714584 0.590 rs4352593 chr5:150269332 T/C cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs919433 0.783 rs787980 chr2:198239225 C/T cg03934865 chr2:198174659 NA 0.57 8.76 0.43 9.31e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs35110281 0.622 rs9977258 chr21:44976485 G/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.45 -0.33 3.8e-10 Mean corpuscular volume; LIHC cis rs881375 0.631 rs2416808 chr9:123706283 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.64 0.34 1.24e-10 Rheumatoid arthritis; LIHC trans rs1728785 1.000 rs1170442 chr16:68574064 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.78e-9 Ulcerative colitis; LIHC cis rs10256972 1.000 rs10256972 chr7:1039003 G/T cg23978390 chr7:1156363 C7orf50 -0.52 -8.07 -0.4 1.22e-14 Longevity;Endometriosis; LIHC cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg01788221 chr16:89496183 ANKRD11 -0.4 -6.23 -0.32 1.36e-9 Multiple myeloma (IgH translocation); LIHC cis rs10197940 0.648 rs7587301 chr2:152347600 A/G cg06191203 chr2:152266755 RIF1 -0.41 -7.17 -0.36 4.8e-12 Lung cancer; LIHC cis rs1865760 0.892 rs9379806 chr6:25940958 G/A cg17691542 chr6:26056736 HIST1H1C 0.4 5.95 0.31 6.6e-9 Height; LIHC cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.55e-21 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs1335636 chr6:8465047 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs2070488 0.965 rs1058945 chr3:38532511 A/G cg24069376 chr3:38537580 EXOG -0.44 -8.05 -0.4 1.41e-14 Electrocardiographic conduction measures; LIHC cis rs6912958 0.781 rs2268993 chr6:88184111 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.4 -7.05 -0.36 9.98e-12 Monocyte percentage of white cells; LIHC cis rs8062405 0.737 rs11861132 chr16:28871860 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs35146811 0.520 rs1015538 chr7:99626035 A/G cg13334819 chr7:99746414 C7orf59 0.5 7.45 0.37 7.51e-13 Coronary artery disease; LIHC cis rs798554 0.660 rs1182196 chr7:2866478 T/G cg13628971 chr7:2884303 GNA12 0.42 6.47 0.33 3.36e-10 Height; LIHC cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg12463550 chr7:65579703 CRCP 0.69 7.15 0.36 5.29e-12 Diabetic kidney disease; LIHC cis rs4819052 0.851 rs914214 chr21:46697820 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.24 0.41 3.82e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11098699 0.821 rs2047582 chr4:124232496 C/A cg09941581 chr4:124220074 SPATA5 0.31 6.16 0.32 2e-9 Mosquito bite size; LIHC cis rs9733 0.596 rs72702556 chr1:150680115 C/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.33e-30 Menopause (age at onset); LIHC cis rs751728 1.000 rs751728 chr6:33764033 C/T cg25922239 chr6:33757077 LEMD2 0.42 7.01 0.35 1.26e-11 Crohn's disease; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg04013166 chr16:89971882 TCF25 0.55 7.23 0.36 3.16e-12 Skin colour saturation; LIHC cis rs12477438 0.798 rs2123686 chr2:99690135 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.54 -0.38 4.32e-13 Chronic sinus infection; LIHC cis rs12744310 0.887 rs28566545 chr1:41783233 G/A cg03962019 chr1:41807865 NA 0.39 6.23 0.32 1.38e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6089584 0.888 rs6061983 chr20:60621202 T/C cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs769267 1.000 rs2074089 chr19:19449603 G/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.21 -0.32 1.52e-9 Tonsillectomy; LIHC cis rs17345786 0.861 rs11707689 chr3:101086475 A/G cg12386194 chr3:101231763 SENP7 0.58 7.6 0.38 2.9e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs270601 0.770 rs4361510 chr5:131599647 C/T cg24060327 chr5:131705240 SLC22A5 -0.53 -6.94 -0.35 1.96e-11 Acylcarnitine levels; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg26218726 chr12:122018391 KDM2B -0.43 -6.17 -0.32 1.9e-9 Neuroblastoma; LIHC cis rs9611565 0.649 rs2413659 chr22:42164862 A/G cg06634786 chr22:41940651 POLR3H 0.55 6.04 0.31 4e-9 Vitiligo; LIHC cis rs3736485 0.966 rs4775958 chr15:51891562 G/C cg08986416 chr15:51914746 DMXL2 -0.41 -6.02 -0.31 4.61e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6424115 0.830 rs2501423 chr1:24199026 A/C cg15997130 chr1:24165203 NA 0.37 7.39 0.37 1.1e-12 Immature fraction of reticulocytes; LIHC cis rs561341 1.000 rs555629 chr17:30294136 T/C cg00745463 chr17:30367425 LRRC37B -0.77 -5.71 -0.3 2.43e-8 Hip circumference adjusted for BMI; LIHC cis rs35110281 0.782 rs9981790 chr21:45045052 G/C cg21573476 chr21:45109991 RRP1B -0.52 -9.8 -0.47 3.81e-20 Mean corpuscular volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12508214 chr8:124553600 FBXO32 0.39 6.22 0.32 1.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg00149659 chr3:10157352 C3orf10 0.65 6.97 0.35 1.63e-11 Alzheimer's disease; LIHC trans rs2797160 1.000 rs1935774 chr6:125996661 A/G cg05039488 chr6:79577232 IRAK1BP1 0.42 6.28 0.32 1.01e-9 Endometrial cancer; LIHC cis rs7208859 0.623 rs11657990 chr17:29124200 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.12 0.4 8.6e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2075371 1.000 rs2544213 chr7:133982867 G/C cg11752832 chr7:134001865 SLC35B4 0.51 7.74 0.39 1.12e-13 Mean platelet volume; LIHC cis rs1914816 0.941 rs2957037 chr15:76485536 A/G cg03037974 chr15:76606532 NA -0.59 -6.2 -0.32 1.67e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs9916302 0.904 rs55660616 chr17:37684990 C/A cg15445000 chr17:37608096 MED1 0.38 5.83 0.3 1.26e-8 Glomerular filtration rate (creatinine); LIHC cis rs67478160 0.643 rs12880167 chr14:104300829 C/T cg08213375 chr14:104286397 PPP1R13B 0.64 12.14 0.55 1.86e-28 Schizophrenia; LIHC trans rs61931739 0.500 rs11053269 chr12:34545307 A/G cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs2163237 0.965 rs6748103 chr2:55986042 C/T cg18811423 chr2:55921094 PNPT1 0.5 7.02 0.35 1.18e-11 IgG glycosylation; LIHC cis rs5753037 0.585 rs5752962 chr22:30188245 A/C cg01021169 chr22:30184971 ASCC2 -0.44 -8.88 -0.43 3.88e-17 Type 1 diabetes; LIHC trans rs1005277 0.540 rs7903942 chr10:37929276 C/T cg17830980 chr10:43048298 ZNF37B 0.43 8.3 0.41 2.46e-15 Extrinsic epigenetic age acceleration; LIHC cis rs1401999 1.000 rs6443924 chr3:183679532 A/G cg05044414 chr3:183734942 ABCC5 0.35 6.16 0.32 2.07e-9 Anterior chamber depth; LIHC cis rs10752881 1.000 rs8179283 chr1:182974602 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 9.86 0.47 2.39e-20 Colorectal cancer; LIHC cis rs9911578 1.000 rs2270097 chr17:56572070 G/A cg12560992 chr17:57184187 TRIM37 -0.96 -17.19 -0.68 3.41e-48 Intelligence (multi-trait analysis); LIHC cis rs13126513 0.519 rs7659550 chr4:100554402 G/T cg05468953 chr4:100565104 NA 0.34 7.32 0.37 1.79e-12 Metabolite levels (MHPG); LIHC cis rs2242116 0.796 rs4587 chr3:46963502 T/C cg27129171 chr3:47204927 SETD2 0.55 8.75 0.43 1.01e-16 Birth weight; LIHC cis rs2549003 1.000 rs9282762 chr5:131822055 T/C cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs986417 0.818 rs12883272 chr14:61015153 A/G cg27398547 chr14:60952738 C14orf39 0.74 8.02 0.4 1.71e-14 Gut microbiota (bacterial taxa); LIHC cis rs12048904 0.619 rs10875347 chr1:101333737 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 10.22 0.48 1.39e-21 Multiple sclerosis; LIHC cis rs6456156 0.586 rs9459862 chr6:167487011 A/G cg23791538 chr6:167370224 RNASET2 0.45 6.8 0.35 4.62e-11 Primary biliary cholangitis; LIHC cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg05564831 chr3:52568323 NT5DC2 0.36 5.95 0.31 6.79e-9 Electroencephalogram traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24995352 chr10:13203403 MCM10 0.46 6.07 0.31 3.31e-9 Pancreatic cancer; LIHC cis rs903552 0.935 rs12907726 chr15:102003626 C/G cg25677261 chr15:102009856 PCSK6 -0.43 -5.92 -0.3 7.76e-9 Diabetic kidney disease; LIHC cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg00343986 chr7:65444356 GUSB 0.44 6.13 0.31 2.49e-9 Aortic root size; LIHC cis rs912057 0.695 rs1294419 chr6:6742549 C/G cg06612196 chr6:6737390 NA 0.52 9.79 0.47 3.98e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC trans rs7618501 0.602 rs2013208 chr3:50129399 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.55 -8.88 -0.43 3.8e-17 Intelligence (multi-trait analysis); LIHC cis rs7408868 0.908 rs757474 chr19:15273624 T/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs9902453 1.000 rs7212497 chr17:28335949 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.74 -0.54 5.79e-27 Coffee consumption (cups per day); LIHC cis rs2276314 1.000 rs4573997 chr18:33552568 C/T cg05985134 chr18:33552581 C18orf21 0.5 5.92 0.3 7.8e-9 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs9467773 1.000 rs28558133 chr6:26531433 G/C cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC cis rs238295 0.805 rs6053486 chr20:5530767 T/G cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -6.86 -0.35 3.22e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs9911578 0.967 rs1588322 chr17:56990099 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg00684032 chr4:1343700 KIAA1530 0.49 7.47 0.37 6.83e-13 Obesity-related traits; LIHC trans rs2739330 0.796 rs2154594 chr22:24254055 A/G cg06437703 chr8:37914619 EIF4EBP1 0.5 7.26 0.37 2.68e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs916888 0.773 rs199448 chr17:44809001 A/G cg15921436 chr17:44337874 NA 0.66 6.74 0.34 6.83e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs4906332 1.000 rs35344594 chr14:103955792 A/G cg17675199 chr6:35436792 RPL10A 0.35 6.89 0.35 2.76e-11 Coronary artery disease; LIHC cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg12310025 chr6:25882481 NA -0.7 -9.23 -0.45 2.83e-18 Intelligence (multi-trait analysis); LIHC cis rs7249142 0.549 rs72997174 chr19:19294389 T/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.34 -5.74 -0.3 2.09e-8 IgG glycosylation; LIHC cis rs9814567 0.806 rs11927540 chr3:134319455 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.57 -9.37 -0.45 9.88e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9326248 1.000 rs9326248 chr11:116999225 A/C cg26566898 chr11:117069891 TAGLN 0.48 7.41 0.37 1.01e-12 Blood protein levels; LIHC cis rs365132 0.875 rs691141 chr5:176323298 A/G cg16309518 chr5:176445507 NA 0.49 8.88 0.43 3.92e-17 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs11864453 0.647 rs3764314 chr16:72127078 T/C cg16558253 chr16:72132732 DHX38 -0.45 -7.26 -0.37 2.55e-12 Fibrinogen levels; LIHC trans rs877282 0.786 rs10904558 chr10:797509 C/T cg22713356 chr15:30763199 NA 1.34 12.54 0.56 6.12e-30 Uric acid levels; LIHC cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.66e-9 Bipolar disorder; LIHC cis rs12824058 0.799 rs4759656 chr12:130815804 G/A cg24838063 chr12:130822603 PIWIL1 0.66 9.79 0.47 4.16e-20 Menopause (age at onset); LIHC cis rs1801251 0.896 rs6719061 chr2:233695885 C/T cg08000102 chr2:233561755 GIGYF2 -0.75 -11.12 -0.52 9.86e-25 Coronary artery disease; LIHC cis rs2635047 0.967 rs9960264 chr18:44606996 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.52 6.89 0.35 2.69e-11 Educational attainment; LIHC trans rs11088226 0.681 rs2833911 chr21:33949629 C/T cg09050820 chr6:167586206 TCP10L2 -0.88 -14.96 -0.63 2.73e-39 Gastritis; LIHC cis rs9457247 0.637 rs9459846 chr6:167441023 T/G cg07741184 chr6:167504864 NA 0.26 6.17 0.32 1.95e-9 Crohn's disease; LIHC cis rs9393777 0.623 rs16891717 chr6:26477143 T/A cg12826209 chr6:26865740 GUSBL1 0.66 6.97 0.35 1.65e-11 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10505247 chr1:207226475 PFKFB2 0.44 6.06 0.31 3.57e-9 Lung function (FEV1/FVC); LIHC trans rs2727020 0.595 rs7924311 chr11:49507573 G/A cg03929089 chr4:120376271 NA -0.89 -17.99 -0.7 2.08e-51 Coronary artery disease; LIHC cis rs716804 0.703 rs4491213 chr11:10306882 G/C cg01453529 chr11:10209919 SBF2 -0.29 -5.87 -0.3 1.01e-8 Neuroticism; LIHC cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg25072359 chr17:41440525 NA 0.39 6.27 0.32 1.09e-9 Menopause (age at onset); LIHC cis rs2108225 0.837 rs6958729 chr7:107451211 A/G cg18560240 chr7:107437656 SLC26A3 0.44 6.89 0.35 2.63e-11 Ulcerative colitis; LIHC cis rs801193 1.000 rs6958520 chr7:66151453 T/C cg11764359 chr7:65958608 NA 0.71 10.56 0.5 9.29e-23 Aortic root size; LIHC cis rs6426558 0.502 rs6697665 chr1:227474665 T/C cg10327440 chr1:227177885 CDC42BPA 0.42 6.33 0.32 7.77e-10 Neutrophil percentage of white cells; LIHC cis rs1997103 1.000 rs4947504 chr7:55409428 T/C cg17469321 chr7:55412551 NA 0.48 7.2 0.36 3.87e-12 QRS interval (sulfonylurea treatment interaction); LIHC trans rs11098499 0.648 rs2002047 chr4:120257228 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.26 0.41 3.23e-15 Corneal astigmatism; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs7959452 0.535 rs7135092 chr12:69658330 T/C cg20891283 chr12:69753455 YEATS4 0.76 13.95 0.6 2.59e-35 Blood protein levels; LIHC cis rs9948 0.786 rs62156233 chr2:97434061 C/G cg01990225 chr2:97406019 LMAN2L -0.7 -6.44 -0.33 4.12e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs4908768 0.539 rs2100888 chr1:8659282 T/A cg20416874 chr1:8611966 RERE -0.61 -11.1 -0.51 1.17e-24 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7927592 0.956 rs11228258 chr11:68254328 A/C cg16797656 chr11:68205561 LRP5 -0.54 -8.71 -0.43 1.34e-16 Total body bone mineral density; LIHC cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.43 -0.56 1.59e-29 Alzheimer's disease; LIHC cis rs4820294 0.669 rs9622678 chr22:38057338 A/G cg10587741 chr22:38071170 LGALS1 0.44 7.97 0.4 2.42e-14 Fat distribution (HIV); LIHC cis rs1949733 0.701 rs2688222 chr4:8473735 C/A cg11789530 chr4:8429930 ACOX3 0.66 8.68 0.43 1.61e-16 Response to antineoplastic agents; LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg18306943 chr3:40428807 ENTPD3 0.42 7.38 0.37 1.21e-12 Renal cell carcinoma; LIHC cis rs6558174 0.802 rs6558170 chr8:22487388 C/G cg03733263 chr8:22462867 KIAA1967 0.42 5.89 0.3 9.06e-9 Breast cancer; LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg18306943 chr3:40428807 ENTPD3 -0.42 -7.46 -0.37 7.36e-13 Renal cell carcinoma; LIHC cis rs4794202 0.700 rs11079797 chr17:45912302 C/T cg10638573 chr17:45915098 SCRN2 0.51 5.99 0.31 5.41e-9 Alzheimer's disease (cognitive decline); LIHC cis rs780096 0.587 rs6743819 chr2:27567407 G/T cg05484376 chr2:27715224 FNDC4 0.34 5.75 0.3 2.03e-8 Total body bone mineral density; LIHC cis rs10463316 0.894 rs6579863 chr5:150761946 A/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.02e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7100689 0.646 rs1815650 chr10:82157464 C/T cg00277334 chr10:82204260 NA -0.47 -6.81 -0.35 4.34e-11 Post bronchodilator FEV1; LIHC cis rs4665809 0.549 rs3828255 chr2:26413252 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.1 12.54 0.56 6.32e-30 Gut microbiome composition (summer); LIHC cis rs9814567 0.964 rs10935113 chr3:134173091 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.57 -10.05 -0.48 5.39e-21 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9309473 1.000 rs10187192 chr2:73713500 T/C cg20560298 chr2:73613845 ALMS1 -0.57 -6.54 -0.33 2.29e-10 Metabolite levels; LIHC cis rs9457247 0.624 rs2239826 chr6:167504880 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -7.5 -0.38 5.58e-13 Crohn's disease; LIHC cis rs6952808 0.771 rs10275045 chr7:1920826 C/T cg22963979 chr7:1858916 MAD1L1 -0.38 -5.96 -0.31 6.13e-9 Bipolar disorder and schizophrenia; LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg05590025 chr7:65112418 INTS4L2 -0.46 -6.93 -0.35 2.1e-11 Calcium levels; LIHC cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg17747265 chr1:1875780 NA -0.58 -11.27 -0.52 2.83e-25 Body mass index; LIHC cis rs644799 0.965 rs566877 chr11:95528045 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs713477 0.654 rs6573030 chr14:55913720 T/G cg13175173 chr14:55914753 NA -0.32 -7.2 -0.36 3.78e-12 Pediatric bone mineral content (femoral neck); LIHC cis rs225245 0.782 rs321599 chr17:33905745 C/T cg05299278 chr17:33885742 SLFN14 0.22 5.78 0.3 1.66e-8 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs8180040 0.934 rs4858811 chr3:47480524 G/C cg27129171 chr3:47204927 SETD2 -0.56 -9.45 -0.46 5.33e-19 Colorectal cancer; LIHC cis rs1559088 0.947 rs12461219 chr19:33550633 C/G cg27124370 chr19:33622961 WDR88 0.46 7.09 0.36 7.93e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4920343 0.698 rs578988 chr1:19077291 T/C cg19637330 chr1:19110922 NA 0.31 5.75 0.3 1.97e-8 Knee osteoarthritis; LIHC cis rs9560113 0.597 rs947170 chr13:112241062 G/A cg10483660 chr13:112241077 NA -0.25 -6.48 -0.33 3.28e-10 Menarche (age at onset); LIHC cis rs7945705 0.818 rs2742552 chr11:8876852 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -9.26 -0.45 2.26e-18 Hemoglobin concentration; LIHC trans rs10511404 1.000 rs10511404 chr3:120518357 G/A cg09889680 chr22:21922804 UBE2L3 -0.51 -6.51 -0.33 2.65e-10 Tumor necrosis factor alpha levels; LIHC trans rs1347297 0.614 rs4894017 chr2:179281062 C/T cg14011486 chr1:26737247 LIN28 0.63 10.08 0.48 4.18e-21 Alzheimer disease and age of onset; LIHC trans rs877282 0.947 rs7475589 chr10:767479 C/G cg22713356 chr15:30763199 NA 1.38 12.4 0.56 2.02e-29 Uric acid levels; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg07061783 chr6:25882402 NA 0.43 5.76 0.3 1.85e-8 Blood metabolite levels; LIHC cis rs10791097 0.694 rs61910787 chr11:130744473 G/A cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg11766577 chr21:47581405 C21orf56 -0.45 -7.55 -0.38 4.01e-13 Testicular germ cell tumor; LIHC cis rs7582180 0.629 rs2309796 chr2:100954385 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.69 0.43 1.51e-16 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.583 rs61253125 chr2:136618178 T/C cg15123519 chr2:136567270 LCT -0.37 -5.92 -0.3 7.82e-9 Corneal structure; LIHC cis rs116095464 0.614 rs4371799 chr5:268192 C/A cg22857025 chr5:266934 NA -1.51 -18.77 -0.71 1.57e-54 Breast cancer; LIHC cis rs1707322 1.000 rs4074225 chr1:46392364 G/C cg06784218 chr1:46089804 CCDC17 0.36 6.31 0.32 8.71e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1801251 1.000 rs13013142 chr2:233600606 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.25 0.52 3.29e-25 Coronary artery disease; LIHC cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg02931644 chr1:25747376 RHCE 0.35 7.35 0.37 1.45e-12 Plateletcrit;Mean corpuscular volume; LIHC cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.5 0.38 5.37e-13 Electroencephalogram traits; LIHC cis rs3806933 0.522 rs13186912 chr5:110456704 A/T cg04022379 chr5:110408740 TSLP -0.55 -8.85 -0.43 4.87e-17 Eosinophilic esophagitis; LIHC cis rs763121 0.853 rs4821798 chr22:39021165 T/C cg14440974 chr22:39074834 NA -0.35 -5.95 -0.31 6.63e-9 Menopause (age at onset); LIHC cis rs875971 0.660 rs2013222 chr7:66035936 C/G cg11764359 chr7:65958608 NA -0.72 -10.9 -0.51 6e-24 Aortic root size; LIHC cis rs6860806 0.507 rs272883 chr5:131668698 A/G cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.82e-31 Breast cancer; LIHC cis rs992157 0.643 rs10191283 chr2:219056755 G/A cg00012203 chr2:219082015 ARPC2 0.88 15.2 0.63 3.17e-40 Colorectal cancer; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg21897413 chr5:176944084 DDX41 -0.42 -6.17 -0.32 1.91e-9 Immature fraction of reticulocytes; LIHC trans rs17685 0.712 rs4552844 chr7:75718095 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6466055 0.777 rs6466053 chr7:104923929 C/T cg04380332 chr7:105027541 SRPK2 0.37 6.86 0.35 3.2e-11 Schizophrenia; LIHC cis rs1215050 0.755 rs1238462 chr4:98850603 A/G cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.61e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11608355 0.545 rs35018715 chr12:109893134 T/C cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs765787 0.530 rs4238376 chr15:45541887 T/C cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC cis rs4268898 0.932 rs7577964 chr2:24598279 A/G cg06627628 chr2:24431161 ITSN2 0.52 7.42 0.37 9.45e-13 Asthma; LIHC cis rs921968 0.607 rs529474 chr2:219463283 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.41 0.41 1.16e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs66887589 0.870 rs2389875 chr4:120557014 G/T cg09307838 chr4:120376055 NA -0.44 -6.39 -0.33 5.52e-10 Diastolic blood pressure; LIHC cis rs9457247 1.000 rs2757042 chr6:167371234 A/T cg07741184 chr6:167504864 NA -0.29 -6.64 -0.34 1.26e-10 Crohn's disease; LIHC cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg05564831 chr3:52568323 NT5DC2 0.38 6.16 0.32 2.07e-9 Bipolar disorder; LIHC cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg16049864 chr8:95962084 TP53INP1 -0.63 -11.91 -0.54 1.32e-27 Type 2 diabetes; LIHC cis rs11763147 1 rs11763147 chr7:65326821 C/T cg18876405 chr7:65276391 NA -0.55 -9.15 -0.44 5.12e-18 Corneal structure; LIHC cis rs2404602 1.000 rs4886818 chr15:76880939 G/A cg23625390 chr15:77176239 SCAPER 0.37 6.17 0.32 1.94e-9 Blood metabolite levels; LIHC cis rs11958404 0.932 rs72818113 chr5:157439825 G/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.671 rs832531 chr5:56228401 A/G cg24531977 chr5:56204891 C5orf35 -0.54 -7.89 -0.39 4.15e-14 Initial pursuit acceleration; LIHC cis rs7512552 0.780 rs2794681 chr1:150321951 C/T cg15654264 chr1:150340011 RPRD2 0.7 11.46 0.53 5.82e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs921968 0.643 rs2556385 chr2:219532905 G/A cg02985541 chr2:219472218 PLCD4 -0.44 -7.99 -0.4 2.04e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg02034447 chr16:89574710 SPG7 0.45 6.76 0.34 5.97e-11 Multiple myeloma (IgH translocation); LIHC cis rs66486766 1 rs66486766 chr15:84806060 G/A cg03959625 chr15:84868606 LOC388152 0.46 5.75 0.3 1.98e-8 Bipolar disorder lithium response (categorical) or schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10162261 chr22:38598048 MAFF -0.42 -6.12 -0.31 2.5e-9 Pancreatic cancer; LIHC cis rs7131987 0.868 rs11050151 chr12:29403008 T/A cg05697976 chr12:29376483 FAR2 0.34 7.0 0.35 1.35e-11 QT interval; LIHC cis rs6088590 1.000 rs6120747 chr20:33449769 T/C cg24642439 chr20:33292090 TP53INP2 0.74 9.72 0.47 6.84e-20 Coronary artery disease; LIHC cis rs7927771 0.524 rs7929014 chr11:47776283 C/T cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs8114671 0.562 rs4911164 chr20:33479488 G/C cg07148914 chr20:33460835 GGT7 0.66 10.06 0.48 5.04e-21 Height; LIHC cis rs703842 0.963 rs923829 chr12:58174306 T/C cg18357645 chr12:58087776 OS9 -0.44 -7.02 -0.35 1.19e-11 Multiple sclerosis; LIHC cis rs4660306 0.848 rs1088099 chr1:45946654 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC 0.65 7.76 0.39 1.01e-13 Homocysteine levels; LIHC cis rs7617773 0.817 rs4131362 chr3:48329036 A/C cg11946769 chr3:48343235 NME6 0.87 11.3 0.52 2.32e-25 Coronary artery disease; LIHC cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg20607798 chr8:58055168 NA 0.6 7.05 0.36 1e-11 Developmental language disorder (linguistic errors); LIHC cis rs1152591 1.000 rs1152591 chr14:64680848 A/G cg21174375 chr14:64681225 SYNE2 0.39 6.05 0.31 3.75e-9 Atrial fibrillation; LIHC cis rs807029 0.577 rs750866 chr10:102761458 A/G cg17130504 chr10:102756923 LZTS2 0.53 7.13 0.36 5.98e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg21724239 chr8:58056113 NA 0.49 6.42 0.33 4.65e-10 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg08888203 chr3:10149979 C3orf24 0.57 6.55 0.33 2.08e-10 Alzheimer's disease; LIHC cis rs34779708 0.733 rs4444023 chr10:35548354 G/A cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7909074 1.000 rs10751360 chr10:45396971 G/A cg05187965 chr10:45406764 TMEM72 -0.27 -6.78 -0.34 5.29e-11 Mean corpuscular volume; LIHC cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg05368731 chr17:41323189 NBR1 0.73 12.71 0.57 1.43e-30 Menopause (age at onset); LIHC cis rs66569888 0.581 rs17271098 chr2:106692818 A/G cg23109721 chr2:106886537 NA 0.58 5.77 0.3 1.77e-8 Facial morphology (factor 23); LIHC cis rs6138458 1.000 rs6114988 chr20:24977586 C/T cg26195577 chr20:24973756 C20orf3 1.21 16.37 0.66 6.78e-45 Blood protein levels; LIHC cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg03452623 chr4:187889614 NA -0.32 -8.28 -0.41 2.87e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs780094 0.585 rs3739095 chr2:27556721 C/T cg17158414 chr2:27665306 KRTCAP3 -0.41 -5.75 -0.3 2.01e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs6762477 0.748 rs9831967 chr3:50217234 C/T cg12257692 chr3:49977190 RBM6 -0.36 -5.76 -0.3 1.89e-8 Menarche (age at onset); LIHC cis rs12142240 0.698 rs55971480 chr1:46823206 G/T cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs1816752 0.817 rs7985394 chr13:25012852 C/G cg02811702 chr13:24901961 NA 0.26 6.61 0.34 1.5e-10 Obesity-related traits; LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg06420487 chr17:61919686 SMARCD2 0.43 5.85 0.3 1.13e-8 Height; LIHC cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg02359409 chr6:42947317 PEX6 -0.49 -6.87 -0.35 3.06e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7212590 0.581 rs8064505 chr17:57838831 G/A cg10252138 chr17:58120427 NA -0.59 -5.88 -0.3 9.59e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs3008870 0.755 rs4655661 chr1:67408828 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.77 0.5 1.73e-23 Lymphocyte percentage of white cells; LIHC cis rs3096299 0.967 rs28689480 chr16:89460093 T/C cg08392591 chr16:89556376 ANKRD11 0.42 6.28 0.32 1.01e-9 Multiple myeloma (IgH translocation); LIHC cis rs12472274 0.529 rs11677996 chr2:239118007 A/G cg17459225 chr2:239074497 NA 0.71 10.83 0.51 1.03e-23 Phospholipid levels (plasma); LIHC cis rs7258465 0.965 rs10409003 chr19:18543054 C/T cg10790698 chr19:18539756 SSBP4 -0.37 -7.49 -0.38 5.79e-13 Breast cancer; LIHC cis rs7618501 0.966 rs9882639 chr3:49799475 A/C cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.34e-11 Intelligence (multi-trait analysis); LIHC cis rs7903847 0.642 rs7084654 chr10:99135262 G/A cg08345082 chr10:99160200 RRP12 -0.37 -6.13 -0.31 2.37e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs1668357 1.000 rs1668357 chr7:38004406 G/T cg04044224 chr2:238499793 RAB17 -0.32 -6.12 -0.31 2.63e-9 Myopia (pathological); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06984945 chr6:26660160 ZNF322A 0.42 6.15 0.32 2.16e-9 Pancreatic cancer; LIHC cis rs7762018 0.891 rs7764839 chr6:170146351 C/A cg19338460 chr6:170058176 WDR27 -0.38 -5.9 -0.3 8.61e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2404602 0.619 rs7342603 chr15:76982625 C/T cg23625390 chr15:77176239 SCAPER 0.36 5.96 0.31 6.35e-9 Blood metabolite levels; LIHC cis rs3741404 0.895 rs1860368 chr11:63994692 T/C cg04317338 chr11:64019027 PLCB3 -0.5 -6.91 -0.35 2.42e-11 Platelet count; LIHC cis rs10464366 0.544 rs4355688 chr7:39158402 C/T cg10621924 chr7:39171070 POU6F2 0.42 6.51 0.33 2.67e-10 IgG glycosylation; LIHC cis rs7607369 0.782 rs639913 chr2:219365971 A/C cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs1008375 1.000 rs4698199 chr4:17656738 G/C cg02297831 chr4:17616191 MED28 0.5 7.81 0.39 6.97e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs780094 0.544 rs2303370 chr2:27651375 C/T cg17158414 chr2:27665306 KRTCAP3 -0.42 -5.74 -0.3 2.06e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs7772486 0.686 rs7744014 chr6:146123818 G/A cg23711669 chr6:146136114 FBXO30 0.64 11.51 0.53 3.76e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 0.663 rs9459835 chr6:167417551 G/T cg23791538 chr6:167370224 RNASET2 -0.61 -10.63 -0.5 5.22e-23 Crohn's disease; LIHC cis rs1198430 1.000 rs946268 chr1:23747766 A/G cg13183780 chr1:23809682 ASAP3 -0.52 -7.56 -0.38 3.72e-13 Total cholesterol levels; LIHC cis rs4407350 1.000 rs5765725 chr22:44921706 A/C cg11695653 chr22:44894386 LDOC1L -0.36 -6.0 -0.31 4.91e-9 Intelligence (multi-trait analysis); LIHC cis rs2286885 1.000 rs741025 chr9:129251792 C/T cg15282417 chr9:129245246 FAM125B 0.39 6.28 0.32 1.02e-9 Intraocular pressure; LIHC cis rs7267979 1.000 rs6083828 chr20:25369918 T/C cg24626310 chr20:25276739 ABHD12;PYGB -0.45 -6.69 -0.34 9.34e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs875971 1.000 rs778696 chr7:65870813 C/G cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs7523273 0.925 rs2745977 chr1:208017360 C/A cg22525895 chr1:207977042 MIR29B2 -0.67 -9.96 -0.47 1.08e-20 Schizophrenia; LIHC cis rs909002 0.800 rs11589306 chr1:32082822 C/G cg13919466 chr1:32135498 COL16A1 -0.32 -6.12 -0.31 2.55e-9 Intelligence (multi-trait analysis); LIHC cis rs12478296 0.786 rs28802397 chr2:243049730 G/A cg06360820 chr2:242988706 NA -0.84 -11.79 -0.54 3.68e-27 Obesity-related traits; LIHC cis rs600806 0.850 rs3931560 chr1:109966718 A/C cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.84 -0.3 1.2e-8 Intelligence (multi-trait analysis); LIHC cis rs12286929 0.577 rs7101437 chr11:115063641 A/G cg04055981 chr11:115044050 NA -0.54 -8.45 -0.42 8.62e-16 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2153535 0.580 rs9406164 chr6:8470048 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC trans rs2243480 1.000 rs958550 chr7:65635679 C/T cg10756647 chr7:56101905 PSPH -1.02 -12.5 -0.56 8.8e-30 Diabetic kidney disease; LIHC cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.69 0.34 9.33e-11 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg11766577 chr21:47581405 C21orf56 0.43 7.15 0.36 5.39e-12 Testicular germ cell tumor; LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg00280220 chr17:61926910 NA 0.44 7.18 0.36 4.43e-12 Prudent dietary pattern; LIHC cis rs5769765 1.000 rs2319458 chr22:50236306 G/A cg02269571 chr22:50332266 NA -0.61 -8.43 -0.41 1e-15 Schizophrenia; LIHC cis rs12220238 1.000 rs111704178 chr10:75957251 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.62 6.38 0.33 5.69e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs67460515 0.892 rs34016896 chr3:160992864 C/T cg17135325 chr3:160939158 NMD3 0.53 7.5 0.38 5.58e-13 Parkinson's disease; LIHC cis rs9921222 0.521 rs11649255 chr16:357140 A/G cg12437481 chr16:420112 MRPL28 -0.55 -7.65 -0.38 2.08e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs35110281 0.837 rs7279958 chr21:45016016 C/A cg01579765 chr21:45077557 HSF2BP -0.33 -6.33 -0.32 7.75e-10 Mean corpuscular volume; LIHC cis rs858239 0.899 rs2268745 chr7:23317600 G/A cg18081818 chr7:23246105 NA -0.4 -6.01 -0.31 4.83e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2439831 0.850 rs544122 chr15:43775732 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.76 11.44 0.53 7.07e-26 Lung cancer in ever smokers; LIHC cis rs10847980 0.590 rs78462864 chr12:123365867 C/T cg07706471 chr12:123319906 HIP1R 0.73 7.48 0.38 6.14e-13 Adiponectin levels; LIHC cis rs2273156 1.000 rs12050402 chr14:35461816 C/T cg16230307 chr14:35515116 FAM177A1 -0.41 -6.04 -0.31 3.96e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs7945705 0.719 rs2012680 chr11:8996059 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -7.08 -0.36 8.37e-12 Hemoglobin concentration; LIHC cis rs7044106 0.791 rs2416799 chr9:123480866 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.9 0.39 3.77e-14 Hip circumference adjusted for BMI; LIHC cis rs8180040 0.676 rs1108301 chr3:47029426 G/A cg27129171 chr3:47204927 SETD2 -0.59 -9.73 -0.47 6.76e-20 Colorectal cancer; LIHC cis rs11122272 0.701 rs7414807 chr1:231476874 G/A cg06096015 chr1:231504339 EGLN1 0.49 9.04 0.44 1.16e-17 Hemoglobin concentration; LIHC cis rs11893307 0.507 rs1465303 chr2:191585440 A/C cg05765582 chr2:191677683 NA 0.29 5.72 0.3 2.39e-8 Mean platelet volume; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.19 -0.32 1.72e-9 Total body bone mineral density; LIHC cis rs4555082 0.834 rs28846738 chr14:105745781 A/G cg06808227 chr14:105710500 BRF1 -0.61 -8.23 -0.41 3.9e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs7520050 0.966 rs6656992 chr1:46333068 C/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.71 0.3 2.42e-8 Red blood cell count;Reticulocyte count; LIHC cis rs769267 1.000 rs2301669 chr19:19453560 C/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.27 -0.32 1.11e-9 Tonsillectomy; LIHC cis rs10870270 0.956 rs10781555 chr10:133745720 G/A cg08754478 chr10:133766260 PPP2R2D -0.55 -8.1 -0.4 9.51e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6089584 0.566 rs55881457 chr20:60608424 G/A cg23262073 chr20:60523788 NA -0.29 -6.03 -0.31 4.28e-9 Body mass index; LIHC cis rs7116495 0.881 rs7924516 chr11:71667989 T/C cg26138937 chr11:71823887 C11orf51 -0.81 -7.95 -0.39 2.76e-14 Severe influenza A (H1N1) infection; LIHC cis rs2404602 0.563 rs12914005 chr15:76765667 A/G cg23625390 chr15:77176239 SCAPER 0.36 5.79 0.3 1.59e-8 Blood metabolite levels; LIHC cis rs9443189 0.530 rs614065 chr6:76315633 G/A cg01950844 chr6:76311363 SENP6 0.88 11.02 0.51 2.2e-24 Prostate cancer; LIHC cis rs6582630 0.638 rs1829584 chr12:38526299 G/T cg26384229 chr12:38710491 ALG10B -0.49 -6.81 -0.35 4.41e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs9467773 0.836 rs1624440 chr6:26433329 G/A cg09904177 chr6:26538194 HMGN4 -0.5 -9.19 -0.44 3.97e-18 Intelligence (multi-trait analysis); LIHC cis rs892961 1.000 rs892961 chr17:75400100 A/T cg05865280 chr17:75406074 SEPT9 0.61 7.64 0.38 2.15e-13 Airflow obstruction; LIHC cis rs1816752 0.905 rs11839006 chr13:25010031 T/C cg22771759 chr13:24902376 NA 0.32 6.7 0.34 8.55e-11 Obesity-related traits; LIHC cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg07414643 chr4:187882934 NA 0.23 5.93 0.31 7.41e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11624085 chr17:8464688 MYH10 0.37 6.18 0.32 1.86e-9 Bilirubin levels; LIHC trans rs800082 0.516 rs1178893 chr3:144239246 A/C cg24215973 chr2:240111563 HDAC4 0.5 6.75 0.34 6.27e-11 Smoking behavior; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg02065141 chr10:135101714 TUBGCP2 0.47 6.07 0.31 3.38e-9 Hip circumference; LIHC cis rs8053891 0.756 rs35800852 chr16:72002105 G/T cg01557791 chr16:72042693 DHODH -0.49 -7.0 -0.35 1.35e-11 Coronary artery disease; LIHC cis rs9911578 1.000 rs8071916 chr17:56660279 A/G cg05425664 chr17:57184151 TRIM37 -0.56 -8.29 -0.41 2.56e-15 Intelligence (multi-trait analysis); LIHC cis rs7188873 1 rs7188873 chr16:24727064 A/G cg00339695 chr16:24857497 SLC5A11 -0.39 -6.47 -0.33 3.49e-10 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.760 rs61954973 chr12:123074168 T/C cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.95 -0.39 2.84e-14 Body mass index; LIHC cis rs1862618 0.525 rs2662019 chr5:56263104 A/G cg24531977 chr5:56204891 C5orf35 0.62 8.4 0.41 1.18e-15 Initial pursuit acceleration; LIHC cis rs2153535 0.505 rs9405395 chr6:8468622 T/A cg07606381 chr6:8435919 SLC35B3 0.8 11.99 0.54 6.68e-28 Motion sickness; LIHC cis rs12594515 0.600 rs12903858 chr15:45972166 A/G cg01629716 chr15:45996671 NA 0.38 6.77 0.34 5.67e-11 Waist circumference;Weight; LIHC trans rs11039798 0.528 rs10839208 chr11:49030456 C/T cg15704280 chr7:45808275 SEPT13 0.58 6.45 0.33 3.81e-10 Axial length; LIHC cis rs35883536 0.708 rs34689792 chr1:101097753 A/G cg14515779 chr1:101123966 NA -0.67 -13.18 -0.58 2.42e-32 Monocyte count; LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs4908768 0.906 rs12402539 chr1:8538303 C/A cg20416874 chr1:8611966 RERE 0.57 9.07 0.44 9.19e-18 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6089584 0.888 rs2146853 chr20:60617908 A/T cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs6061231 1.000 rs6061231 chr20:60956917 C/A cg06026331 chr20:60912101 LAMA5 0.4 5.79 0.3 1.56e-8 Colorectal cancer; LIHC cis rs6120849 0.754 rs6088667 chr20:33566722 A/C cg24642439 chr20:33292090 TP53INP2 0.68 7.81 0.39 7.1e-14 Protein C levels; LIHC cis rs10256972 0.669 rs10229964 chr7:1051776 A/G cg04025307 chr7:1156635 C7orf50 0.38 6.01 0.31 4.63e-9 Longevity;Endometriosis; LIHC cis rs2777491 0.915 rs8032838 chr15:41605632 G/A cg18705301 chr15:41695430 NDUFAF1 -0.55 -8.15 -0.4 7.18e-15 Ulcerative colitis; LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg02951883 chr7:2050386 MAD1L1 -0.85 -15.27 -0.64 1.69e-40 Bipolar disorder and schizophrenia; LIHC cis rs9733 0.526 rs11204698 chr1:150659545 G/A cg18016565 chr1:150552671 MCL1 0.59 11.57 0.53 2.44e-26 Tonsillectomy; LIHC cis rs77669868 0.929 rs3782007 chr11:114066438 A/G cg01914181 chr11:114070210 ZBTB16 -0.61 -8.61 -0.42 2.74e-16 Monocyte percentage of white cells; LIHC trans rs7395662 0.571 rs4882020 chr11:48615658 C/T cg15704280 chr7:45808275 SEPT13 -0.47 -7.01 -0.35 1.29e-11 HDL cholesterol; LIHC cis rs6088580 0.608 rs2105109 chr20:32971932 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs611744 0.781 rs656406 chr8:109173843 G/A cg21045802 chr8:109455806 TTC35 0.59 10.06 0.48 5.19e-21 Dupuytren's disease; LIHC cis rs2153535 0.504 rs9328472 chr6:8470848 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08819884 chr3:3168225 TRNT1 -0.49 -6.36 -0.33 6.6e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg03264133 chr6:25882463 NA -0.59 -8.36 -0.41 1.65e-15 Blood metabolite levels; LIHC cis rs514406 0.679 rs541852 chr1:53256834 A/G cg08859206 chr1:53392774 SCP2 0.46 7.4 0.37 1.05e-12 Monocyte count; LIHC cis rs523522 0.962 rs3742052 chr12:120966921 A/G cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs10876993 0.855 rs1689585 chr12:58080140 A/G cg18357645 chr12:58087776 OS9 -0.51 -8.28 -0.41 2.76e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs2204008 0.683 rs12370288 chr12:38127740 G/A cg26384229 chr12:38710491 ALG10B 0.85 10.57 0.5 8.82e-23 Bladder cancer; LIHC cis rs74181299 0.533 rs7585500 chr2:65372337 A/C cg05010058 chr2:65284262 CEP68 -0.35 -5.71 -0.3 2.39e-8 Pulse pressure; LIHC cis rs763121 0.853 rs2076028 chr22:39150450 G/A cg14440974 chr22:39074834 NA -0.39 -6.28 -0.32 1.05e-9 Menopause (age at onset); LIHC cis rs7582720 0.943 rs72932583 chr2:203869847 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.1 0.31 2.88e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2180341 1.000 rs9388561 chr6:127634921 C/T cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs7487075 0.504 rs7312682 chr12:46647998 C/T cg15584813 chr12:47219626 SLC38A4 0.32 5.93 0.31 7.37e-9 Itch intensity from mosquito bite; LIHC cis rs722599 0.683 rs7145246 chr14:75242394 A/T cg11812906 chr14:75593930 NEK9 -0.45 -6.83 -0.35 3.8e-11 IgG glycosylation; LIHC cis rs7945718 0.935 rs1609442 chr11:12795418 T/A cg25843174 chr11:12811716 TEAD1 0.37 8.67 0.42 1.8e-16 Educational attainment (years of education); LIHC cis rs7772486 0.597 rs6570732 chr6:146245151 G/A cg05347473 chr6:146136440 FBXO30 -0.48 -6.87 -0.35 3.06e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs6835098 0.692 rs7657374 chr4:174065756 A/T cg27433088 chr4:174089019 GALNT7 0.29 5.72 0.3 2.31e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC trans rs11153056 0.500 rs72939809 chr6:107537039 G/C cg12119218 chr10:70287206 SLC25A16 -0.45 -6.11 -0.31 2.67e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs9733 0.519 rs2184833 chr1:150675483 C/T cg17724175 chr1:150552817 MCL1 0.5 10.01 0.48 7.57e-21 Tonsillectomy; LIHC cis rs2180341 1.000 rs9375499 chr6:127618072 T/C cg27446573 chr6:127587934 RNF146 1.03 15.95 0.65 3.18e-43 Breast cancer; LIHC cis rs6748734 1.000 rs7604393 chr2:241825034 T/G cg04034577 chr2:241836375 C2orf54 -0.41 -8.13 -0.4 7.83e-15 Urinary metabolites; LIHC cis rs11958404 0.932 rs6895484 chr5:157429159 T/C cg05962755 chr5:157440814 NA 1.06 11.94 0.54 1.02e-27 IgG glycosylation; LIHC cis rs2072499 1.000 rs2540173 chr1:156188214 A/G cg25208724 chr1:156163844 SLC25A44 0.92 15.83 0.65 9.93e-43 Testicular germ cell tumor; LIHC cis rs208520 1.000 rs208527 chr6:66957209 A/C cg07460842 chr6:66804631 NA -0.65 -7.0 -0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs4243830 0.737 rs11122085 chr1:6597861 T/C cg22792644 chr1:6614718 TAS1R1;NOL9 0.89 9.99 0.48 8.52e-21 Body mass index; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs10876993 0.890 rs7976852 chr12:58100551 T/G cg15848620 chr12:58087721 OS9 -0.55 -7.41 -0.37 1.03e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg07167872 chr1:205819463 PM20D1 0.6 8.79 0.43 7.43e-17 Menarche (age at onset); LIHC cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg18252515 chr7:66147081 NA -1.25 -16.5 -0.67 2.19e-45 Diabetic kidney disease; LIHC cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.08 0.44 9.04e-18 Bipolar disorder; LIHC cis rs1005277 0.579 rs2474608 chr10:38457109 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs903552 0.736 rs11858491 chr15:102007456 C/T cg06707286 chr15:102010195 PCSK6 0.5 7.36 0.37 1.41e-12 Diabetic kidney disease; LIHC cis rs3820500 0.585 rs2256057 chr1:117942591 T/C cg20383390 chr1:117909022 MAN1A2 0.46 5.87 0.3 1.03e-8 Pneumonia; LIHC cis rs3768716 0.500 rs777329 chr2:215742595 A/G cg04004882 chr2:215674386 BARD1 -0.51 -6.98 -0.35 1.57e-11 Neuroblastoma; LIHC cis rs4268898 0.552 rs11125454 chr2:24373669 T/C cg06627628 chr2:24431161 ITSN2 0.48 7.05 0.36 9.83e-12 Asthma; LIHC cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.81 7.64 0.38 2.2e-13 Platelet count; LIHC cis rs2276314 1.000 rs56050783 chr18:33553791 A/G cg05985134 chr18:33552581 C18orf21 0.49 5.86 0.3 1.11e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs1348850 0.914 rs2060929 chr2:178280031 T/C cg27490568 chr2:178487706 NA 0.36 5.76 0.3 1.87e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6942756 1.000 rs66864889 chr7:128952560 G/A cg02491457 chr7:128862824 NA -0.65 -9.48 -0.46 4.25e-19 White matter hyperintensity burden; LIHC cis rs7613875 0.620 rs7430334 chr3:50078221 T/C cg21467203 chr3:49911342 NA 0.52 9.35 0.45 1.18e-18 Body mass index; LIHC cis rs950169 0.509 rs71395455 chr15:85153804 A/G cg12863693 chr15:85201151 NMB 0.43 6.01 0.31 4.71e-9 Schizophrenia; LIHC cis rs1691799 0.867 rs1495497 chr12:66770020 A/T cg16791601 chr12:66731901 HELB -0.5 -10.75 -0.5 2.08e-23 White blood cell count (basophil); LIHC cis rs2070488 0.965 rs2284820 chr3:38562579 C/T cg24069376 chr3:38537580 EXOG -0.38 -6.99 -0.35 1.42e-11 Electrocardiographic conduction measures; LIHC cis rs7178375 1.000 rs7176351 chr15:31208727 G/A cg19680485 chr15:31195859 MTMR15 -0.52 -5.73 -0.3 2.18e-8 Hypertriglyceridemia; LIHC cis rs6952808 0.929 rs12699483 chr7:1975624 C/G cg04267008 chr7:1944627 MAD1L1 -0.65 -10.43 -0.49 2.62e-22 Bipolar disorder and schizophrenia; LIHC cis rs921968 0.608 rs7598056 chr2:219352511 A/C cg17980119 chr2:219472607 PLCD4 0.36 6.21 0.32 1.55e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.18 -0.4 5.48e-15 Lymphocyte counts; LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.91 -0.3 8.13e-9 Total body bone mineral density; LIHC cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg18357526 chr6:26021779 HIST1H4A 0.41 6.26 0.32 1.15e-9 Height; LIHC cis rs7512552 0.839 rs2867894 chr1:150452912 T/A cg15654264 chr1:150340011 RPRD2 0.67 11.01 0.51 2.37e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9303401 0.659 rs62081316 chr17:56781499 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.13 0.58 3.68e-32 Cognitive test performance; LIHC cis rs4700695 0.614 rs251285 chr5:65211137 A/T cg21114390 chr5:65439923 SFRS12 0.46 5.83 0.3 1.3e-8 Facial morphology (factor 19); LIHC cis rs9443189 0.570 rs276684 chr6:76427065 A/G cg01950844 chr6:76311363 SENP6 -0.85 -10.42 -0.49 3.01e-22 Prostate cancer; LIHC cis rs2979489 0.786 rs62508366 chr8:30369499 G/A cg26383811 chr8:30366931 RBPMS -0.7 -11.11 -0.51 1.1e-24 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs918629 0.716 rs6897997 chr5:95270241 C/T cg10483112 chr5:95245456 ELL2 -0.37 -6.31 -0.32 8.49e-10 IgG glycosylation; LIHC cis rs2153535 0.580 rs9392223 chr6:8468650 G/A cg07606381 chr6:8435919 SLC35B3 0.8 11.99 0.54 6.68e-28 Motion sickness; LIHC cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg13047869 chr3:10149882 C3orf24 0.51 6.63 0.34 1.3100000000000001e-10 Alzheimer's disease; LIHC cis rs28475163 1.000 rs28475163 chr11:327143 G/A cg03071500 chr11:325964 NA -0.46 -7.29 -0.37 2.13e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg26354017 chr1:205819088 PM20D1 0.76 11.38 0.52 1.15e-25 Menarche (age at onset); LIHC cis rs9303401 0.614 rs3087762 chr17:56568680 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.92 12.58 0.56 4.35e-30 Cognitive test performance; LIHC cis rs1499614 1.000 rs1638731 chr7:66144679 C/T cg12463550 chr7:65579703 CRCP 0.66 6.92 0.35 2.21e-11 Gout; LIHC cis rs875971 0.862 rs778736 chr7:65813848 C/T cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.38e-9 Aortic root size; LIHC cis rs7208859 0.623 rs80355557 chr17:29154421 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.01 0.4 1.79e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600806 0.778 rs2787015 chr1:110009434 A/C cg10127483 chr1:110009974 SYPL2 0.47 5.81 0.3 1.46e-8 Intelligence (multi-trait analysis); LIHC cis rs9616064 0.740 rs6520049 chr22:46996309 C/T cg25730555 chr22:47059586 GRAMD4 0.36 5.76 0.3 1.87e-8 Urate levels in obese individuals; LIHC cis rs11190604 1.000 rs2298074 chr10:102247526 G/C cg07080220 chr10:102295463 HIF1AN 0.52 7.12 0.36 6.34e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs8180040 0.783 rs11710121 chr3:47351501 T/G cg27129171 chr3:47204927 SETD2 -0.5 -8.01 -0.4 1.77e-14 Colorectal cancer; LIHC cis rs477692 0.603 rs10829602 chr10:131326790 G/A cg05714579 chr10:131428358 MGMT 0.39 6.24 0.32 1.31e-9 Response to temozolomide; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.75 0.62 1.8e-38 Prudent dietary pattern; LIHC trans rs75804782 0.641 rs55844289 chr2:239323207 C/T cg01134436 chr17:81009848 B3GNTL1 0.78 6.35 0.32 7.01e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg01518246 chr11:63870912 FLRT1;MACROD1 0.49 7.2 0.36 3.88e-12 Mean platelet volume; LIHC cis rs2559856 1.000 rs2559854 chr12:102090246 C/T cg12924262 chr12:102091054 CHPT1 0.48 7.61 0.38 2.61e-13 Blood protein levels; LIHC cis rs9527 0.571 rs4917985 chr10:104624072 C/T cg15744005 chr10:104629667 AS3MT -0.45 -10.59 -0.5 7.39e-23 Arsenic metabolism; LIHC cis rs2731664 0.792 rs2630765 chr5:176876825 T/C cg23176889 chr5:176863531 GRK6 -0.72 -12.62 -0.56 2.99e-30 Intelligence (multi-trait analysis); LIHC cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.53 7.43 0.37 8.79e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs950173 1.000 rs950173 chr2:172570419 G/A cg13550731 chr2:172543902 DYNC1I2 -0.84 -7.93 -0.39 3.23e-14 Hippocampal volume; LIHC cis rs829883 0.714 rs249847 chr12:98867716 C/T cg25150519 chr12:98850993 NA 0.67 10.64 0.5 4.79e-23 Colorectal adenoma (advanced); LIHC cis rs9427116 0.502 rs6699825 chr1:154582970 A/G cg17218026 chr1:154582156 ADAR 0.36 7.2 0.36 3.78e-12 Blood protein levels; LIHC cis rs2439831 0.850 rs61390361 chr15:44159842 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.7 9.78 0.47 4.54e-20 Lung cancer in ever smokers; LIHC cis rs3768617 0.528 rs10737241 chr1:183098208 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.47 0.49 1.94e-22 Fuchs's corneal dystrophy; LIHC cis rs6426558 0.537 rs6692080 chr1:227390162 C/T cg10327440 chr1:227177885 CDC42BPA -0.45 -6.89 -0.35 2.62e-11 Neutrophil percentage of white cells; LIHC cis rs2180341 0.694 rs2875972 chr6:127585522 T/C cg24812749 chr6:127587940 RNF146 0.73 10.7 0.5 3.12e-23 Breast cancer; LIHC cis rs3744061 0.776 rs9916811 chr17:74749273 C/T cg13533061 chr17:74712429 JMJD6 0.39 5.96 0.31 6.17e-9 Retinal arteriolar caliber; LIHC cis rs7918232 0.627 rs6482588 chr10:27308307 G/C cg14442939 chr10:27389572 ANKRD26 0.59 5.76 0.3 1.84e-8 Breast cancer; LIHC cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs898097 0.528 rs2243523 chr17:80680449 G/T cg02711726 chr17:80685570 FN3KRP 0.37 6.92 0.35 2.17e-11 Breast cancer; LIHC cis rs5769765 0.908 rs9616390 chr22:50314289 G/C cg02269571 chr22:50332266 NA -0.76 -10.01 -0.48 7.66e-21 Schizophrenia; LIHC trans rs12620999 1.000 rs11689249 chr2:238083542 T/A cg15676719 chr1:167598521 RCSD1 -0.39 -6.91 -0.35 2.35e-11 Systemic lupus erythematosus; LIHC cis rs17685 0.753 rs10251863 chr7:75790192 T/C cg01364799 chr7:75623366 TMEM120A -0.52 -7.84 -0.39 5.62e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4474465 1.000 rs10793314 chr11:78174196 G/C cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg10717766 chr19:5134118 KDM4B -0.4 -6.09 -0.31 3.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2576037 0.526 rs2571026 chr18:44561795 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.7 -10.99 -0.51 2.84e-24 Personality dimensions; LIHC cis rs67311347 0.577 rs2371129 chr3:40248393 C/T cg00656387 chr3:40428638 ENTPD3 -0.43 -6.77 -0.34 5.48e-11 Renal cell carcinoma; LIHC cis rs911119 0.955 rs61035931 chr20:23595714 A/G cg16589663 chr20:23618590 CST3 0.72 7.6 0.38 2.88e-13 Chronic kidney disease; LIHC cis rs4901869 0.931 rs12891570 chr14:59334338 T/A cg02291164 chr14:59296302 NA 0.47 5.94 0.31 6.94e-9 Panic disorder; LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg09417038 chr21:47716443 C21orf57 0.47 6.87 0.35 2.97e-11 Testicular germ cell tumor; LIHC cis rs9473924 0.542 rs6901576 chr6:50926064 G/T cg14470998 chr6:50812995 TFAP2B -0.79 -7.48 -0.38 6.18e-13 Body mass index; LIHC cis rs8081395 0.801 rs2665404 chr17:57875396 A/G cg02344993 chr17:57696989 CLTC 0.45 7.4 0.37 1.04e-12 White blood cell count; LIHC cis rs72772090 1.000 rs72772092 chr5:96046912 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.58 -6.63 -0.34 1.33e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg03874509 chr1:107600012 PRMT6 0.75 11.96 0.54 8.65e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4820539 0.966 rs2267000 chr22:23455366 A/G cg14186256 chr22:23484241 RTDR1 0.92 19.27 0.72 1.53e-56 Bone mineral density; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.3 0.61 1.09e-36 Prudent dietary pattern; LIHC cis rs709400 0.770 rs7142883 chr14:104066645 G/A cg26031613 chr14:104095156 KLC1 1.15 14.94 0.63 3.25e-39 Body mass index; LIHC cis rs903552 0.736 rs11858491 chr15:102007456 C/T cg04789225 chr15:102009795 PCSK6 0.43 5.9 0.3 8.85e-9 Diabetic kidney disease; LIHC cis rs8060686 0.516 rs8048364 chr16:68253324 T/G cg05110241 chr16:68378359 PRMT7 -0.51 -6.07 -0.31 3.45e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs7529073 0.545 rs1431985 chr1:214148246 C/T cg24083324 chr1:214162604 PROX1 -0.46 -6.79 -0.34 4.95e-11 Schizophrenia; LIHC cis rs7727544 0.735 rs272879 chr5:131670546 C/G cg24060327 chr5:131705240 SLC22A5 -0.59 -8.44 -0.42 9.19e-16 Blood metabolite levels; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC cis rs10791097 0.667 rs1893019 chr11:130756664 C/G cg12179176 chr11:130786555 SNX19 0.85 13.94 0.6 2.63e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.27 0.52 2.81e-25 Prudent dietary pattern; LIHC cis rs694739 0.964 rs2510066 chr11:64052447 C/T cg23796481 chr11:64053134 BAD;GPR137 0.6 8.28 0.41 2.74e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs6977660 0.619 rs10223937 chr7:19787697 C/T cg07541023 chr7:19748670 TWISTNB 0.41 6.33 0.32 7.57e-10 Thyroid stimulating hormone; LIHC cis rs7927771 1.000 rs34128973 chr11:47851376 C/T cg20135002 chr11:47629003 NA -0.53 -8.91 -0.43 3e-17 Subjective well-being; LIHC cis rs17685 0.712 rs11764119 chr7:75812358 T/G cg04592579 chr7:75616294 TMEM120A 0.4 6.88 0.35 2.8e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2153535 0.580 rs6900007 chr6:8474035 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs716804 0.566 rs7927874 chr11:10324191 T/C cg01453529 chr11:10209919 SBF2 -0.3 -5.74 -0.3 2.08e-8 Neuroticism; LIHC cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg03396347 chr1:1875803 NA -0.44 -8.02 -0.4 1.67e-14 Body mass index; LIHC cis rs5769707 0.681 rs4622843 chr22:50036916 T/G cg01652190 chr22:50026171 C22orf34 -0.33 -7.47 -0.37 6.55e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7786877 0.521 rs4729607 chr7:100326744 T/A cg20848291 chr7:100343083 ZAN -0.49 -7.1 -0.36 7.27e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6582630 0.519 rs11495699 chr12:38286219 G/T cg13010199 chr12:38710504 ALG10B 0.52 6.08 0.31 3.14e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs2230307 0.536 rs490669 chr1:100484430 C/T cg24955406 chr1:100503596 HIAT1 0.62 6.15 0.32 2.14e-9 Carotid intima media thickness; LIHC trans rs2727020 0.636 rs10839275 chr11:49438962 T/A cg03929089 chr4:120376271 NA -0.85 -16.43 -0.66 3.86e-45 Coronary artery disease; LIHC cis rs3812111 0.646 rs9481609 chr6:116489854 T/C cg08036074 chr6:116424633 NT5DC1 -0.52 -8.69 -0.43 1.49e-16 Age-related macular degeneration; LIHC cis rs2067615 0.524 rs10778505 chr12:107143126 G/C cg15890332 chr12:107067104 RFX4 0.27 6.29 0.32 9.52e-10 Heart rate; LIHC cis rs2836950 0.509 rs11088466 chr21:40580017 T/A cg17971929 chr21:40555470 PSMG1 -0.38 -5.8 -0.3 1.54e-8 Menarche (age at onset); LIHC cis rs12295403 0.964 rs34364314 chr11:18691674 G/A cg09887367 chr11:18690185 NA -0.39 -6.45 -0.33 3.86e-10 Ovarian reserve; LIHC cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg06634786 chr22:41940651 POLR3H -0.8 -8.09 -0.4 1.02e-14 Vitiligo; LIHC cis rs12478296 0.581 rs4973645 chr2:242993577 T/C cg05760424 chr2:242988095 NA -0.48 -6.87 -0.35 3.08e-11 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14671666 chr5:41904456 C5orf51 -0.48 -6.49 -0.33 3.1e-10 Pancreatic cancer; LIHC cis rs1707322 1.000 rs4660336 chr1:46487976 T/C cg03146154 chr1:46216737 IPP -0.48 -7.88 -0.39 4.28e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg18252515 chr7:66147081 NA -1.31 -17.56 -0.69 1.13e-49 Diabetic kidney disease; LIHC cis rs875971 0.862 rs1643375 chr7:65872677 T/C cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs2882877 0.610 rs13008848 chr2:190445284 C/G cg10752008 chr2:190445175 SLC40A1 0.61 7.58 0.38 3.29e-13 Mean corpuscular hemoglobin concentration; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg12931157 chr6:41040265 C6orf130;NFYA -0.45 -6.63 -0.34 1.3e-10 Alopecia areata; LIHC cis rs7584330 0.518 rs13420503 chr2:238437623 G/A cg08992911 chr2:238395768 MLPH 0.51 5.96 0.31 6.22e-9 Prostate cancer; LIHC cis rs11122272 0.735 rs2808595 chr1:231526238 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.39 0.45 8.49e-19 Hemoglobin concentration; LIHC cis rs6430585 0.528 rs75667274 chr2:136682486 C/T cg07169764 chr2:136633963 MCM6 1.26 19.13 0.72 5.57e-56 Corneal structure; LIHC cis rs34779708 0.966 rs113170867 chr10:35450147 C/T cg04310649 chr10:35416472 CREM -0.43 -5.72 -0.3 2.33e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2439831 0.850 rs8023458 chr15:44080939 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.39 0.33 5.53e-10 Lung cancer in ever smokers; LIHC cis rs2153535 0.542 rs9378553 chr6:8472632 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs763121 0.719 rs9610995 chr22:39057763 C/T cg14440974 chr22:39074834 NA -0.43 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC trans rs1814175 0.645 rs2140602 chr11:50022800 G/C cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs6912958 0.781 rs9444512 chr6:88223397 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.96 -0.4 2.58e-14 Monocyte percentage of white cells; LIHC cis rs7131987 0.834 rs1989478 chr12:29442229 C/T cg14222432 chr12:29376421 FAR2 0.35 6.89 0.35 2.67e-11 QT interval; LIHC cis rs3749237 0.636 rs1568662 chr3:49521263 A/G cg06212747 chr3:49208901 KLHDC8B 0.46 6.01 0.31 4.66e-9 Resting heart rate; LIHC cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.66e-9 Bipolar disorder; LIHC cis rs910316 0.737 rs175049 chr14:75481368 C/T cg08847533 chr14:75593920 NEK9 -0.87 -17.84 -0.69 8.39e-51 Height; LIHC cis rs6500602 0.963 rs7201012 chr16:4480682 C/G cg08645402 chr16:4508243 NA 0.36 6.75 0.34 6.5e-11 Schizophrenia; LIHC cis rs986417 0.551 rs1956553 chr14:60952298 T/A cg27398547 chr14:60952738 C14orf39 0.83 9.68 0.46 9.59e-20 Gut microbiota (bacterial taxa); LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg14709524 chr16:89940631 TCF25 -0.5 -6.82 -0.35 4.09e-11 Skin colour saturation; LIHC cis rs950169 0.922 rs11630507 chr15:85095725 A/G cg03959625 chr15:84868606 LOC388152 0.47 6.65 0.34 1.19e-10 Schizophrenia; LIHC cis rs6952808 1.000 rs12699404 chr7:1894022 A/T cg20295408 chr7:1910781 MAD1L1 -0.52 -7.37 -0.37 1.31e-12 Bipolar disorder and schizophrenia; LIHC cis rs2933343 0.953 rs2933344 chr3:128658715 A/G cg24203234 chr3:128598194 ACAD9 0.44 5.95 0.31 6.6e-9 IgG glycosylation; LIHC cis rs2153535 0.580 rs6914276 chr6:8450435 A/T cg21535247 chr6:8435926 SLC35B3 -0.61 -7.89 -0.39 4.08e-14 Motion sickness; LIHC cis rs71327718 1 rs71327718 chr3:125592857 C/G cg18651192 chr3:125677574 NA 0.41 5.75 0.3 1.94e-8 Metabolite levels (HVA/5-HIAA ratio); LIHC cis rs3008870 1.000 rs12117131 chr1:67451922 C/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03701779 chr10:74927978 FAM149B1;ECD 0.45 6.57 0.33 1.9e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs116979167 0.514 rs1706915 chr7:105196437 A/G cg19920283 chr7:105172520 RINT1 0.47 5.74 0.3 2.09e-8 Bipolar disorder (body mass index interaction); LIHC cis rs4908768 0.594 rs11121228 chr1:8830642 T/C cg20416874 chr1:8611966 RERE 0.45 6.47 0.33 3.37e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7172677 1.000 rs1021382 chr15:75417398 A/G cg09165964 chr15:75287851 SCAMP5 -0.41 -5.77 -0.3 1.82e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7312933 0.966 rs7977365 chr12:42513127 G/A cg01256987 chr12:42539512 GXYLT1 -0.42 -7.02 -0.35 1.2e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs943466 0.911 rs111352628 chr6:33742490 A/G cg25922239 chr6:33757077 LEMD2 -0.48 -6.04 -0.31 3.96e-9 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs3768617 0.510 rs2296291 chr1:183079509 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.66 0.5 4.09e-23 Fuchs's corneal dystrophy; LIHC cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs1443512 0.812 rs1561987 chr12:54335268 C/T cg17410650 chr12:54324560 NA -0.33 -5.94 -0.31 6.93e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg00656387 chr3:40428638 ENTPD3 0.42 6.95 0.35 1.81e-11 Renal cell carcinoma; LIHC cis rs12474201 0.862 rs13025595 chr2:46977893 A/G cg06386533 chr2:46925753 SOCS5 0.58 6.74 0.34 6.76e-11 Height; LIHC cis rs138857 0.515 rs9616373 chr22:50308597 G/A cg09182678 chr22:50328711 NA -0.69 -7.92 -0.39 3.46e-14 Mean platelet volume; LIHC cis rs9768139 0.935 rs10155946 chr7:158122116 C/T cg25566285 chr7:158114605 PTPRN2 -0.26 -7.69 -0.38 1.63e-13 Calcium levels; LIHC cis rs8031584 0.679 rs34017474 chr15:31230611 T/C cg08109568 chr15:31115862 NA -0.31 -5.78 -0.3 1.7e-8 Huntington's disease progression; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg21668880 chr6:34759629 UHRF1BP1 -0.43 -6.3 -0.32 8.92e-10 Triglycerides; LIHC cis rs1538970 0.816 rs4633317 chr1:45985157 T/C cg24296786 chr1:45957014 TESK2 -0.47 -6.48 -0.33 3.24e-10 Platelet count; LIHC cis rs9325144 0.505 rs6582691 chr12:38806894 T/C cg26384229 chr12:38710491 ALG10B -0.54 -8.51 -0.42 5.58e-16 Morning vs. evening chronotype; LIHC cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg21782813 chr7:2030301 MAD1L1 0.49 8.42 0.41 1.07e-15 Bipolar disorder and schizophrenia; LIHC cis rs7582180 0.629 rs11682557 chr2:100948008 C/A cg14675211 chr2:100938903 LONRF2 0.53 8.37 0.41 1.45e-15 Intelligence (multi-trait analysis); LIHC cis rs3812111 0.809 rs11965969 chr6:116452203 T/G cg08036074 chr6:116424633 NT5DC1 -0.52 -8.84 -0.43 5.2e-17 Age-related macular degeneration; LIHC cis rs9303401 0.614 rs35057477 chr17:57097064 G/A cg25039879 chr17:56429692 SUPT4H1 0.75 8.46 0.42 7.96e-16 Cognitive test performance; LIHC trans rs11146838 1 rs11146838 chr10:39149977 A/T cg17830980 chr10:43048298 ZNF37B -0.53 -9.97 -0.47 9.82e-21 Breast cancer; LIHC cis rs600806 0.850 rs10858085 chr1:109914983 A/G cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.17 -0.36 4.54e-12 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25889035 chr2:236826311 AGAP1 0.4 6.2 0.32 1.59e-9 Longevity; LIHC cis rs8038465 0.622 rs60696711 chr15:73873005 C/A cg15420318 chr15:73925796 NPTN 0.48 7.06 0.36 9.48e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10847980 0.590 rs75217947 chr12:123346177 G/C cg25930673 chr12:123319894 HIP1R 1.15 12.96 0.57 1.56e-31 Adiponectin levels; LIHC cis rs35110281 0.837 rs12627667 chr21:45071396 A/C cg01579765 chr21:45077557 HSF2BP -0.33 -6.37 -0.33 6.16e-10 Mean corpuscular volume; LIHC cis rs3812111 0.677 rs1204838 chr6:116515224 C/A cg08036074 chr6:116424633 NT5DC1 -0.41 -6.51 -0.33 2.63e-10 Age-related macular degeneration; LIHC cis rs9300255 0.544 rs1790123 chr12:123659542 C/T cg00376283 chr12:123451042 ABCB9 0.61 6.11 0.31 2.73e-9 Neutrophil percentage of white cells; LIHC cis rs8072100 0.777 rs9914653 chr17:45537395 T/C cg08085267 chr17:45401833 C17orf57 -0.54 -8.11 -0.4 9.18e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs933688 1.000 rs2367526 chr5:90740525 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.2 0.66 3.29e-44 Smoking behavior; LIHC cis rs2153535 0.580 rs1034273 chr6:8468145 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs7165170 0.678 rs13379889 chr15:91195039 A/G cg26821196 chr15:91095069 CRTC3 -0.37 -6.88 -0.35 2.8e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4629710 0.538 rs11754401 chr6:131582197 G/A cg12606694 chr6:131520996 AKAP7 0.63 7.14 0.36 5.55e-12 Multiple myeloma (IgH translocation); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02802775 chr11:31391443 DNAJC24;DCDC1 -0.41 -6.49 -0.33 3e-10 Pancreatic cancer; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs10876993 0.928 rs1689592 chr12:58057773 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.57 -0.33 1.84e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs7131987 0.903 rs11050161 chr12:29420049 A/G cg12903224 chr12:29470962 FAR2 -0.42 -6.8 -0.35 4.72e-11 QT interval; LIHC cis rs7552404 0.960 rs61797339 chr1:76189946 G/T cg03433033 chr1:76189801 ACADM 0.65 9.2 0.45 3.71e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs240764 0.817 rs240145 chr6:101079610 A/C cg09795085 chr6:101329169 ASCC3 0.53 7.45 0.37 7.93e-13 Neuroticism; LIHC cis rs2361718 0.631 rs12601637 chr17:78142455 T/C cg09238746 chr17:78121135 EIF4A3 -0.63 -10.5 -0.49 1.6e-22 Yeast infection; LIHC cis rs748404 0.650 rs518261 chr15:43573429 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.5 8.5 0.42 5.94e-16 Lung cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg16823064 chr1:19206559 ALDH4A1 0.42 6.27 0.32 1.06e-9 Hepatitis; LIHC cis rs801193 0.967 rs2707849 chr7:66152712 T/C cg11764359 chr7:65958608 NA 0.71 10.56 0.5 9.29e-23 Aortic root size; LIHC cis rs7937890 0.695 rs17557844 chr11:14262559 A/G cg22961513 chr11:14280813 SPON1 0.42 5.99 0.31 5.46e-9 Mitochondrial DNA levels; LIHC cis rs826838 0.904 rs10876086 chr12:39188208 C/A cg26384229 chr12:38710491 ALG10B 0.85 11.0 0.51 2.59e-24 Heart rate; LIHC cis rs6088580 0.634 rs6059875 chr20:33086090 T/G cg08999081 chr20:33150536 PIGU 0.68 13.52 0.59 1.12e-33 Glomerular filtration rate (creatinine); LIHC cis rs11955398 0.678 rs12522801 chr5:59978406 A/G cg02684056 chr5:59996105 DEPDC1B 0.41 6.09 0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs477692 0.685 rs3852507 chr10:131399616 G/T cg19680672 chr10:131412579 MGMT 0.41 6.25 0.32 1.22e-9 Response to temozolomide; LIHC cis rs3106136 1.000 rs3106134 chr4:95128091 A/G cg11021082 chr4:95130006 SMARCAD1 -0.47 -8.56 -0.42 3.78e-16 Capecitabine sensitivity; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg16132339 chr22:24313637 DDTL;DDT -0.64 -10.28 -0.49 9.11e-22 Urinary 1,3-butadiene metabolite levels in smokers; LIHC trans rs7217932 0.571 rs763368 chr17:69877392 C/T cg08017189 chr16:85680248 KIAA0182 -0.38 -6.29 -0.32 9.99e-10 Bone mineral density; LIHC cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.74 0.34 6.72e-11 Diabetic kidney disease; LIHC cis rs9457247 0.715 rs6923582 chr6:167437162 T/A cg23791538 chr6:167370224 RNASET2 -0.51 -7.8 -0.39 7.67e-14 Crohn's disease; LIHC cis rs1801251 0.963 rs35362030 chr2:233612845 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.13 0.52 9.15e-25 Coronary artery disease; LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs7615952 0.688 rs12485622 chr3:125710739 T/C cg05084668 chr3:125655381 ALG1L -0.43 -6.95 -0.35 1.89e-11 Blood pressure (smoking interaction); LIHC cis rs6429082 0.818 rs696248 chr1:235668511 C/A cg26050004 chr1:235667680 B3GALNT2 0.48 7.35 0.37 1.48e-12 Adiposity; LIHC cis rs2204008 0.744 rs1115514 chr12:38280140 C/T cg26384229 chr12:38710491 ALG10B 0.83 10.59 0.5 7.75e-23 Bladder cancer; LIHC cis rs4555082 1.000 rs4555082 chr14:105758964 C/T cg13114125 chr14:105738426 BRF1 -0.7 -9.36 -0.45 1.08e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs250677 1.000 rs36079 chr5:148430504 G/A cg12140854 chr5:148520817 ABLIM3 -0.42 -6.06 -0.31 3.5e-9 Breast cancer; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg03122602 chr16:89799836 ZNF276 0.4 6.21 0.32 1.52e-9 Immature fraction of reticulocytes; LIHC cis rs7447593 0.666 rs10866705 chr5:176801131 G/T cg16006841 chr5:176797999 RGS14 -0.58 -10.48 -0.49 1.78e-22 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs9430161 0.645 rs6675082 chr1:11033797 T/C cg27631724 chr1:11040367 C1orf127 0.36 6.46 0.33 3.56e-10 Ewing sarcoma; LIHC cis rs4073582 0.595 rs10896104 chr11:66001869 C/T cg16950941 chr11:66035639 RAB1B 0.6 9.01 0.44 1.51e-17 Gout; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg15684274 chr1:892857 NOC2L 0.44 6.31 0.32 8.47e-10 Longevity; LIHC cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg11211951 chr8:145729740 GPT -0.25 -5.87 -0.3 1.04e-8 Age at first birth; LIHC cis rs12368653 1.000 rs12368653 chr12:58133256 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.45 6.33 0.32 7.66e-10 Multiple sclerosis; LIHC cis rs17666538 0.535 rs896522 chr8:616991 A/G cg07234876 chr8:600039 NA 0.91 7.14 0.36 5.67e-12 IgG glycosylation; LIHC cis rs4845459 0.967 rs4845454 chr1:152592184 C/T cg20634798 chr1:152595351 LCE3A -0.3 -5.85 -0.3 1.12e-8 Psoriasis; LIHC cis rs2455601 0.882 rs11042105 chr11:8894510 G/C cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -5.81 -0.3 1.4e-8 Schizophrenia; LIHC cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.71 -0.34 8.26e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9911578 0.935 rs2302189 chr17:56584205 A/C cg12560992 chr17:57184187 TRIM37 -0.96 -16.94 -0.68 3.59e-47 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.779 rs28495013 chr4:120375831 A/C cg09307838 chr4:120376055 NA 0.77 11.96 0.54 8.88e-28 Corneal astigmatism; LIHC trans rs1814175 0.645 rs10839456 chr11:49964093 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -19.81 -0.73 1.07e-58 Height; LIHC cis rs208520 0.837 rs208498 chr6:66931560 G/A cg07460842 chr6:66804631 NA -0.76 -8.39 -0.41 1.34e-15 Exhaled nitric oxide output; LIHC cis rs7224737 1.000 rs9889640 chr17:40293497 C/T cg20291162 chr17:40259547 DHX58 -0.4 -6.38 -0.33 5.82e-10 Fibrinogen levels; LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg21951975 chr1:209979733 IRF6 0.45 7.14 0.36 5.48e-12 Cleft lip with or without cleft palate; LIHC cis rs6499255 0.951 rs12595869 chr16:69729794 T/G cg15192750 chr16:69999425 NA 0.44 6.7 0.34 8.36e-11 IgE levels; LIHC cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg03517284 chr6:25882590 NA 0.65 8.3 0.41 2.52e-15 Intelligence (multi-trait analysis); LIHC cis rs6429082 0.818 rs61836206 chr1:235638754 C/G cg26050004 chr1:235667680 B3GALNT2 0.49 7.44 0.37 7.99e-13 Adiposity; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15803506 chr10:135125704 ZNF511 -0.39 -6.15 -0.32 2.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs477895 0.713 rs3802933 chr11:63988102 C/T cg18225595 chr11:63971243 STIP1 0.68 8.49 0.42 6.35e-16 Mean platelet volume; LIHC cis rs7223966 1.000 rs2854218 chr17:61942940 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.54 6.59 0.34 1.62e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs473651 0.935 rs559579 chr2:239339501 G/C cg18131467 chr2:239335373 ASB1 0.8 12.57 0.56 4.87e-30 Multiple system atrophy; LIHC cis rs10847980 0.590 rs1696326 chr12:123311981 A/G cg07706471 chr12:123319906 HIP1R -0.71 -8.07 -0.4 1.19e-14 Adiponectin levels; LIHC cis rs7615952 0.673 rs7632557 chr3:125634881 G/C cg05084668 chr3:125655381 ALG1L -0.6 -8.51 -0.42 5.7e-16 Blood pressure (smoking interaction); LIHC cis rs10876993 0.821 rs1678522 chr12:58049923 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.79 -0.34 5.05e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs9733 0.596 rs11582840 chr1:150688487 A/G cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg00343986 chr7:65444356 GUSB 0.44 6.24 0.32 1.29e-9 Aortic root size; LIHC cis rs1728785 1.000 rs1170445 chr16:68573064 G/T cg02972257 chr16:68554789 NA -0.56 -6.45 -0.33 3.89e-10 Ulcerative colitis; LIHC cis rs10838687 0.932 rs4752973 chr11:47269159 T/C cg25783544 chr11:47291846 MADD 0.47 6.22 0.32 1.46e-9 Proinsulin levels; LIHC cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg27170947 chr2:26402098 FAM59B 0.62 6.48 0.33 3.24e-10 Gut microbiome composition (summer); LIHC trans rs1814175 0.511 rs61905634 chr11:49819736 G/A cg03929089 chr4:120376271 NA -0.91 -18.87 -0.71 6.43e-55 Height; LIHC cis rs78545713 0.649 rs16891464 chr6:26235300 A/G cg16070018 chr6:26224392 HIST1H3E 0.69 7.41 0.37 1e-12 Iron status biomarkers (total iron binding capacity); LIHC cis rs7772486 0.764 rs7745696 chr6:146162829 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.87 0.3 1.04e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg14557232 chr4:1368966 KIAA1530 0.4 6.24 0.32 1.27e-9 Immature fraction of reticulocytes; LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg14004847 chr7:1930337 MAD1L1 0.55 8.11 0.4 9.47e-15 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.97 0.8 4.54e-79 Prudent dietary pattern; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.95 -0.31 6.51e-9 Total body bone mineral density; LIHC cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg23758822 chr17:41437982 NA 0.96 17.71 0.69 2.87e-50 Menopause (age at onset); LIHC cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs2710642 0.815 rs6545971 chr2:63074986 A/T cg17519650 chr2:63277830 OTX1 0.53 8.04 0.4 1.45e-14 LDL cholesterol levels;LDL cholesterol; LIHC cis rs8071789 1.000 rs8071789 chr17:38006333 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.13 0.36 5.82e-12 Selective IgA deficiency; LIHC cis rs7727544 0.684 rs270602 chr5:131656700 T/C cg24060327 chr5:131705240 SLC22A5 -0.61 -8.92 -0.43 2.98e-17 Blood metabolite levels; LIHC cis rs9682041 0.561 rs9856511 chr3:170140165 C/G cg11886554 chr3:170076028 SKIL 0.76 5.85 0.3 1.15e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs68170813 0.523 rs7777976 chr7:106888594 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs9911578 1.000 rs2009948 chr17:56611920 A/C cg05425664 chr17:57184151 TRIM37 0.58 8.67 0.42 1.82e-16 Intelligence (multi-trait analysis); LIHC cis rs12478296 1.000 rs73007138 chr2:243007041 C/T cg18898632 chr2:242989856 NA -0.67 -7.87 -0.39 4.69e-14 Obesity-related traits; LIHC cis rs4788570 0.566 rs10468265 chr16:71476943 T/C cg06353428 chr16:71660113 MARVELD3 -1.13 -10.16 -0.48 2.27e-21 Intelligence (multi-trait analysis); LIHC cis rs8114671 0.562 rs3746450 chr20:33508588 G/T cg07148914 chr20:33460835 GGT7 0.65 9.86 0.47 2.42e-20 Height; LIHC cis rs9858542 0.953 rs6446272 chr3:49463287 G/A cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4843747 0.671 rs28671027 chr16:88116323 G/A cg00677901 chr16:88017247 BANP 0.51 7.96 0.4 2.5e-14 Menopause (age at onset); LIHC cis rs5769707 0.568 rs2011097 chr22:50018069 A/G cg01652190 chr22:50026171 C22orf34 -0.35 -7.82 -0.39 6.61e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2075371 0.966 rs1646676 chr7:133999267 G/A cg20476274 chr7:133979776 SLC35B4 0.74 12.13 0.55 2.1e-28 Mean platelet volume; LIHC cis rs12477438 0.798 rs7606635 chr2:99644782 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.2 -0.41 4.92e-15 Chronic sinus infection; LIHC cis rs6570726 0.818 rs9399555 chr6:145877554 T/C cg23711669 chr6:146136114 FBXO30 0.65 11.78 0.54 3.99e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs8053891 0.673 rs12444854 chr16:72024490 G/A cg01557791 chr16:72042693 DHODH -0.45 -6.69 -0.34 8.9e-11 Coronary artery disease; LIHC cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg23978390 chr7:1156363 C7orf50 0.53 7.78 0.39 8.66e-14 Longevity;Endometriosis; LIHC cis rs12762955 0.561 rs2620942 chr10:1048398 C/T cg26597838 chr10:835615 NA 0.46 5.83 0.3 1.26e-8 Response to angiotensin II receptor blocker therapy; LIHC cis rs1348850 0.567 rs1527401 chr2:178522104 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.24 0.41 3.6e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg10883421 chr6:151773342 RMND1;C6orf211 0.68 11.54 0.53 3.08e-26 Menarche (age at onset); LIHC cis rs7904368 0.754 rs12253908 chr10:16853358 T/C cg14835575 chr10:16859367 RSU1 0.65 8.84 0.43 5.07e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs60871478 1.000 rs62432899 chr7:826542 G/C cg05535760 chr7:792225 HEATR2 0.97 13.44 0.59 2.33e-33 Cerebrospinal P-tau181p levels; LIHC cis rs1461503 0.932 rs6589962 chr11:122843535 G/A cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.19 -0.32 1.69e-9 Colorectal cancer; LIHC cis rs7264396 0.836 rs961020 chr20:34182069 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -8.92 -0.43 2.97e-17 Total cholesterol levels; LIHC cis rs1580019 0.885 rs1610141 chr7:32498435 C/T cg07520158 chr7:32535189 LSM5;AVL9 0.49 6.53 0.33 2.43e-10 Cognitive ability; LIHC cis rs7772486 0.686 rs9373473 chr6:146082282 A/G cg23711669 chr6:146136114 FBXO30 0.58 10.82 0.5 1.17e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7927771 1.000 rs35624992 chr11:47615798 G/C cg20307385 chr11:47447363 PSMC3 -0.44 -5.75 -0.3 1.96e-8 Subjective well-being; LIHC cis rs4638749 0.677 rs6755598 chr2:108827674 G/C cg06795125 chr2:108905320 SULT1C2 -0.29 -5.75 -0.3 1.94e-8 Blood pressure; LIHC cis rs8027181 0.797 rs8033580 chr15:72994968 C/A cg03441853 chr15:73075003 ADPGK 0.28 5.93 0.31 7.45e-9 Triglyceride levels; LIHC cis rs11758351 1.000 rs75921373 chr6:26191843 C/T cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs3741404 0.560 rs17699798 chr11:63898806 C/G cg18225595 chr11:63971243 STIP1 -0.6 -9.25 -0.45 2.51e-18 Platelet count; LIHC cis rs1559088 0.625 rs10411739 chr19:33616327 T/C cg27124370 chr19:33622961 WDR88 0.59 8.94 0.44 2.42e-17 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6693567 0.565 rs834235 chr1:150362154 C/T cg15654264 chr1:150340011 RPRD2 0.49 8.13 0.4 7.9e-15 Migraine; LIHC cis rs7666738 0.830 rs13119913 chr4:98977983 G/T cg05340658 chr4:99064831 C4orf37 0.72 13.24 0.58 1.37e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs1580019 0.961 rs766660 chr7:32499077 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.79 12.06 0.55 3.86e-28 Cognitive ability; LIHC cis rs4555082 0.957 rs2975216 chr14:105713134 T/C cg06808227 chr14:105710500 BRF1 -0.62 -8.84 -0.43 5.04e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs769267 0.965 rs2017964 chr19:19387149 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg12311346 chr5:56204834 C5orf35 -0.57 -7.51 -0.38 5.28e-13 Initial pursuit acceleration; LIHC cis rs17401966 0.838 rs4846206 chr1:10310258 G/C cg19773385 chr1:10388646 KIF1B -0.4 -7.27 -0.37 2.46e-12 Hepatocellular carcinoma; LIHC cis rs10423674 0.526 rs12462498 chr19:18832950 A/G cg12034943 chr19:18811790 CRTC1 0.36 5.91 0.3 8.33e-9 Menarche (age at onset); LIHC cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1185460 0.565 rs1182922 chr11:118932859 G/A cg23280166 chr11:118938394 VPS11 -0.45 -6.16 -0.32 2.02e-9 Coronary artery disease; LIHC cis rs72781680 0.716 rs2712050 chr2:24059408 A/C cg08917208 chr2:24149416 ATAD2B 0.62 6.44 0.33 4.09e-10 Lymphocyte counts; LIHC cis rs425277 0.958 rs262687 chr1:2117155 G/A cg24578937 chr1:2090814 PRKCZ 0.5 8.59 0.42 3.17e-16 Height; LIHC cis rs9910055 0.530 rs2269905 chr17:42294462 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.42 7.31 0.37 1.84e-12 Total body bone mineral density; LIHC cis rs8017423 0.569 rs10141476 chr14:90823351 C/T cg04374321 chr14:90722782 PSMC1 -0.49 -7.26 -0.37 2.56e-12 Mortality in heart failure; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg05565475 chr9:136223383 SURF2;SURF1 -0.37 -6.24 -0.32 1.33e-9 Eotaxin levels; LIHC cis rs637571 0.544 rs55704213 chr11:65730002 C/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.82 0.3 1.38e-8 Eosinophil percentage of white cells; LIHC cis rs7617773 0.746 rs4130995 chr3:48358255 C/T cg11946769 chr3:48343235 NME6 0.63 8.63 0.42 2.28e-16 Coronary artery disease; LIHC cis rs7542375 0.507 rs2484697 chr1:221094718 A/G cg16008148 chr1:221062819 NA 0.3 6.53 0.33 2.36e-10 Obesity-related traits; LIHC cis rs7131987 0.868 rs10771508 chr12:29414211 G/A cg21486233 chr12:29375141 FAR2 0.31 6.25 0.32 1.22e-9 QT interval; LIHC trans rs16962242 1.000 rs10220272 chr13:104049710 G/T cg12071008 chr17:76457640 DNAH17 0.46 6.09 0.31 3.01e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11971779 0.584 rs7786469 chr7:139094621 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs2204008 0.536 rs12368354 chr12:38042798 G/A cg26384229 chr12:38710491 ALG10B 0.85 10.57 0.5 9e-23 Bladder cancer; LIHC cis rs5753037 0.543 rs131267 chr22:30147861 A/G cg01021169 chr22:30184971 ASCC2 -0.31 -5.87 -0.3 1.02e-8 Type 1 diabetes; LIHC cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg05564831 chr3:52568323 NT5DC2 0.35 5.93 0.31 7.59e-9 Electroencephalogram traits; LIHC cis rs3806843 0.569 rs753279 chr5:140023818 A/G cg19875535 chr5:140030758 IK -0.38 -6.7 -0.34 8.8e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg24549020 chr5:56110836 MAP3K1 -0.52 -6.8 -0.35 4.57e-11 Initial pursuit acceleration; LIHC cis rs13191362 1.000 rs73035021 chr6:163000716 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6674176 0.628 rs7556565 chr1:44416090 C/T cg12908607 chr1:44402522 ARTN -0.49 -8.41 -0.41 1.16e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7617480 0.648 rs6796790 chr3:48780317 G/A cg07636037 chr3:49044803 WDR6 0.74 9.63 0.46 1.45e-19 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27227643 chr15:59949760 GTF2A2 -0.43 -6.06 -0.31 3.69e-9 Pancreatic cancer; LIHC trans rs7618501 0.633 rs6792892 chr3:49995518 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.57 9.36 0.45 1.1e-18 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.953 rs12354639 chr10:963681 G/A cg20503657 chr10:835505 NA 0.89 10.61 0.5 6.2e-23 Eosinophil percentage of granulocytes; LIHC cis rs3540 0.554 rs12443252 chr15:91064690 C/T cg22089800 chr15:90895588 ZNF774 -0.55 -7.69 -0.38 1.6e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2404602 0.684 rs3910756 chr15:76945369 C/T cg03037974 chr15:76606532 NA -0.5 -8.07 -0.4 1.22e-14 Blood metabolite levels; LIHC cis rs3806843 1.000 rs4451093 chr5:140158542 A/G cg26395211 chr5:140044315 WDR55 0.43 6.35 0.32 6.94e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7927592 0.763 rs1193699 chr11:68249480 C/G cg16797656 chr11:68205561 LRP5 0.52 9.26 0.45 2.24e-18 Total body bone mineral density; LIHC cis rs2404602 0.647 rs11072631 chr15:77132909 T/C cg23625390 chr15:77176239 SCAPER -0.54 -8.92 -0.43 2.81e-17 Blood metabolite levels; LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg18538332 chr22:24372958 LOC391322 -0.65 -9.95 -0.47 1.21e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs7618501 1.000 rs9855505 chr3:49792158 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.81 -0.63 1.12e-38 Intelligence (multi-trait analysis); LIHC cis rs713477 0.654 rs998871 chr14:55918302 G/A cg13175173 chr14:55914753 NA -0.31 -6.79 -0.34 4.91e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs858239 0.600 rs4321896 chr7:23128056 G/A cg23682824 chr7:23144976 KLHL7 0.42 6.26 0.32 1.14e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg06558623 chr16:89946397 TCF25 1.01 15.7 0.65 3.23e-42 Skin colour saturation; LIHC trans rs7613875 0.620 rs7624030 chr3:50071279 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.53 -0.33 2.39e-10 Body mass index; LIHC cis rs769267 0.896 rs11882123 chr19:19386339 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs6499255 1.000 rs12596679 chr16:69822680 A/G cg15192750 chr16:69999425 NA -0.45 -6.85 -0.35 3.48e-11 IgE levels; LIHC cis rs9918079 0.560 rs4698402 chr4:15629803 G/A cg24225360 chr4:15471699 CC2D2A -0.38 -6.01 -0.31 4.81e-9 Obesity-related traits; LIHC cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.77 0.39 8.99e-14 Bipolar disorder; LIHC cis rs9303401 0.580 rs34076823 chr17:57114497 C/G cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.75 0.54 5.11e-27 Cognitive test performance; LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.88 0.57 3.25e-31 Prudent dietary pattern; LIHC cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg04944784 chr2:26401820 FAM59B 0.71 9.3 0.45 1.76e-18 Gut microbiome composition (summer); LIHC cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg02359409 chr6:42947317 PEX6 -0.45 -6.0 -0.31 5.07e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2153535 0.580 rs2143356 chr6:8517675 C/T cg23788917 chr6:8435910 SLC35B3 0.62 8.74 0.43 1.08e-16 Motion sickness; LIHC cis rs7149337 0.805 rs3007069 chr14:51597392 G/A cg23942311 chr14:51606299 NA 0.35 7.29 0.37 2.17e-12 Cancer; LIHC cis rs12477438 0.520 rs2969379 chr2:99776686 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.38 0.61 5.11e-37 Chronic sinus infection; LIHC cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg03806693 chr22:41940476 POLR3H -1.1 -12.99 -0.57 1.23e-31 Vitiligo; LIHC cis rs6088580 0.624 rs6120645 chr20:33025171 C/T cg08999081 chr20:33150536 PIGU 0.67 13.28 0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs600806 0.850 rs4970846 chr1:109946095 A/C cg08911820 chr1:110026001 ATXN7L2 -0.57 -6.93 -0.35 2.14e-11 Intelligence (multi-trait analysis); LIHC cis rs7432375 0.901 rs9836231 chr3:136414321 C/T cg21827317 chr3:136751795 NA -0.44 -5.8 -0.3 1.49e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs3820068 0.705 rs11583306 chr1:15860803 A/G cg17385448 chr1:15911702 AGMAT -0.4 -6.39 -0.33 5.31e-10 Systolic blood pressure; LIHC cis rs11588062 0.601 rs11579255 chr1:46806959 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.47 7.29 0.37 2.22e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6831352 0.918 rs13127153 chr4:100058121 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg05484376 chr2:27715224 FNDC4 0.39 6.61 0.34 1.46e-10 Total body bone mineral density; LIHC cis rs801193 0.569 rs2659893 chr7:66199993 G/A cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.34e-11 Aortic root size; LIHC cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg22963979 chr7:1858916 MAD1L1 -0.42 -6.66 -0.34 1.12e-10 Bipolar disorder and schizophrenia; LIHC cis rs780094 0.585 rs3739095 chr2:27556721 C/T cg21747090 chr2:27597821 SNX17 -0.43 -6.52 -0.33 2.49e-10 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs3924048 0.559 rs6541037 chr1:12626155 A/G cg00291366 chr1:12616550 NA 0.37 7.58 0.38 3.32e-13 Optic cup area; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.68 11.02 0.51 2.22e-24 Height; LIHC cis rs6430585 0.702 rs1042712 chr2:136545844 C/G cg07169764 chr2:136633963 MCM6 -1.1 -16.35 -0.66 8.27e-45 Corneal structure; LIHC cis rs9790314 1.000 rs9870059 chr3:161017240 T/C cg03342759 chr3:160939853 NMD3 -0.72 -8.78 -0.43 7.96e-17 Morning vs. evening chronotype; LIHC cis rs3099143 1.000 rs3099143 chr15:77104856 A/C cg21673338 chr15:77095150 SCAPER -0.52 -7.64 -0.38 2.16e-13 Recalcitrant atopic dermatitis; LIHC cis rs17685 0.753 rs8200 chr7:75696606 C/G cg04610667 chr7:75704037 NA 0.33 5.95 0.31 6.71e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7412746 0.611 rs4970985 chr1:150887442 C/T cg18016565 chr1:150552671 MCL1 -0.5 -9.63 -0.46 1.39e-19 Melanoma; LIHC cis rs17685 0.753 rs6976532 chr7:75681094 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.29 -0.32 9.91e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4665809 1.000 rs10170359 chr2:26272219 G/T cg27170947 chr2:26402098 FAM59B -0.66 -8.22 -0.41 4.16e-15 Gut microbiome composition (summer); LIHC cis rs1499614 1.000 rs1267818 chr7:66107024 C/T cg05590025 chr7:65112418 INTS4L2 -0.54 -5.83 -0.3 1.26e-8 Gout; LIHC cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg01017244 chr2:74357527 NA 0.63 11.41 0.53 9.06e-26 Gestational age at birth (maternal effect); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15620385 chr12:26986279 ITPR2 0.42 6.04 0.31 3.98e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6424115 0.830 rs2503000 chr1:24197898 C/G cg10978503 chr1:24200527 CNR2 0.34 8.25 0.41 3.46e-15 Immature fraction of reticulocytes; LIHC cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg06481639 chr22:41940642 POLR3H -0.73 -7.27 -0.37 2.49e-12 Vitiligo; LIHC cis rs72627509 0.638 rs12642622 chr4:57902276 G/A cg26694713 chr4:57773883 REST 0.6 7.46 0.37 7.4e-13 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs4942242 0.512 rs9533551 chr13:44187120 G/C cg19169023 chr15:41853346 TYRO3 -0.54 -7.78 -0.39 8.58e-14 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs1144333 0.655 rs5745465 chr1:76346832 A/G cg10523679 chr1:76189770 ACADM 0.45 5.94 0.31 7.15e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T ch.3.541014R chr3:25654052 TOP2B -0.43 -6.08 -0.31 3.15e-9 Hepatitis; LIHC cis rs4746818 1.000 rs6480384 chr10:70890757 C/T cg11621586 chr10:70884670 VPS26A 0.88 14.57 0.62 1e-37 Left atrial antero-posterior diameter; LIHC cis rs35110281 0.805 rs4818843 chr21:45006607 C/T cg21573476 chr21:45109991 RRP1B -0.56 -10.49 -0.49 1.62e-22 Mean corpuscular volume; LIHC cis rs9324022 0.929 rs9635184 chr14:101173056 C/T cg18089426 chr14:101175970 NA 0.5 6.15 0.32 2.19e-9 Plateletcrit; LIHC cis rs2836950 0.501 rs2836984 chr21:40700949 A/C cg06238570 chr21:40685208 BRWD1 -0.46 -7.44 -0.37 8.15e-13 Menarche (age at onset); LIHC cis rs2404602 0.684 rs57682236 chr15:76868478 G/A cg23625390 chr15:77176239 SCAPER -0.53 -8.81 -0.43 6.55e-17 Blood metabolite levels; LIHC cis rs2933343 0.649 rs1683786 chr3:128626952 T/C cg24203234 chr3:128598194 ACAD9 0.44 6.2 0.32 1.61e-9 IgG glycosylation; LIHC cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg08645402 chr16:4508243 NA 0.38 7.15 0.36 5.33e-12 Schizophrenia; LIHC trans rs12310956 0.532 rs1352209 chr12:33983408 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.69 0.34 9.11e-11 Morning vs. evening chronotype; LIHC cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg06212747 chr3:49208901 KLHDC8B -0.64 -9.01 -0.44 1.47e-17 Menarche (age at onset); LIHC cis rs12135062 0.755 rs1553287 chr1:3101277 G/A cg25382214 chr1:3105252 PRDM16 -0.28 -6.14 -0.32 2.28e-9 Migraine; LIHC cis rs2204008 0.550 rs11495600 chr12:38126654 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs4474465 1.000 rs10793319 chr11:78217237 G/A cg27205649 chr11:78285834 NARS2 0.38 5.79 0.3 1.57e-8 Alzheimer's disease (survival time); LIHC cis rs4700695 0.841 rs957526 chr5:65345830 A/G cg21114390 chr5:65439923 SFRS12 0.5 6.71 0.34 8.23e-11 Facial morphology (factor 19); LIHC cis rs332507 0.601 rs3772777 chr3:124372449 G/A cg05980111 chr3:124395277 KALRN 0.31 6.04 0.31 4.13e-9 Plateletcrit; LIHC cis rs2075371 0.933 rs431306 chr7:133955974 A/T cg20476274 chr7:133979776 SLC35B4 0.75 12.88 0.57 3.27e-31 Mean platelet volume; LIHC cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs11671005 0.568 rs73068329 chr19:59080325 C/T cg25952890 chr19:58913133 NA 0.68 6.92 0.35 2.18e-11 Mean platelet volume; LIHC cis rs7020830 0.898 rs13290794 chr9:37183628 C/T cg14294708 chr9:37120828 ZCCHC7 1.16 25.99 0.81 5.69e-83 Schizophrenia; LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg06601766 chr17:61851465 DDX42;CCDC47 -0.5 -7.65 -0.38 2.06e-13 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.95 0.57 1.78e-31 Prudent dietary pattern; LIHC cis rs3091242 0.933 rs61775174 chr1:25787313 G/A cg09222892 chr1:25734099 RHCE 0.48 8.89 0.43 3.54e-17 Erythrocyte sedimentation rate; LIHC cis rs6424115 0.679 rs2294495 chr1:24075876 C/T cg15997130 chr1:24165203 NA -0.36 -6.18 -0.32 1.84e-9 Immature fraction of reticulocytes; LIHC cis rs4822044 0.617 rs13054514 chr22:42130383 A/G cg03806693 chr22:41940476 POLR3H 0.79 9.02 0.44 1.41e-17 Cannabis dependence symptom count; LIHC trans rs13217239 0.511 rs4546474 chr6:27224633 C/T cg24820996 chr19:17791300 UNC13A -0.31 -6.13 -0.31 2.48e-9 Schizophrenia; LIHC cis rs7772486 0.754 rs702306 chr6:145991029 T/C cg05347473 chr6:146136440 FBXO30 -0.36 -5.72 -0.3 2.34e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs875971 1.000 rs2036264 chr7:65799904 G/A cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.22e-10 Aortic root size; LIHC cis rs9790314 1.000 rs336567 chr3:161073046 A/G cg03342759 chr3:160939853 NMD3 -0.7 -8.34 -0.41 1.86e-15 Morning vs. evening chronotype; LIHC cis rs12477438 0.501 rs6753063 chr2:99801469 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.21 0.61 2.47e-36 Chronic sinus infection; LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg12143784 chr7:64541923 NA -0.35 -6.08 -0.31 3.2e-9 Calcium levels; LIHC cis rs9296404 1 rs9296404 chr6:42925803 T/C cg02353165 chr6:42928485 GNMT 0.78 12.04 0.55 4.43e-28 Plasma homocysteine levels (post-methionine load test); LIHC cis rs11098499 0.954 rs6822679 chr4:120402702 A/C cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.65e-29 Corneal astigmatism; LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg16070018 chr6:26224392 HIST1H3E 0.59 7.45 0.37 7.55e-13 Gout;Renal underexcretion gout; LIHC cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.95 -9.35 -0.45 1.15e-18 Platelet count; LIHC cis rs2836974 0.666 rs1888487 chr21:40683259 A/G cg06238570 chr21:40685208 BRWD1 -0.55 -8.83 -0.43 5.38e-17 Cognitive function; LIHC cis rs12479064 0.703 rs28382977 chr2:100018304 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -6.88 -0.35 2.9100000000000002e-11 Chronic sinus infection; LIHC cis rs4908768 0.906 rs55830087 chr1:8681550 C/T cg20416874 chr1:8611966 RERE 0.54 7.66 0.38 1.91e-13 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9649465 1.000 rs2052128 chr7:123380405 T/A cg03229431 chr7:123269106 ASB15 -0.37 -8.04 -0.4 1.53e-14 Migraine; LIHC cis rs1670533 0.872 rs13108222 chr4:1054256 C/A cg27284194 chr4:1044797 NA 0.6 8.93 0.43 2.6e-17 Recombination rate (females); LIHC cis rs868036 0.681 rs9920643 chr15:68104314 C/T cg24579218 chr15:68104479 NA -0.34 -5.88 -0.3 9.59e-9 Restless legs syndrome; LIHC cis rs10739663 0.520 rs1566362 chr9:128163132 C/T cg14078157 chr9:128172775 NA 0.51 8.37 0.41 1.48e-15 Resting heart rate; LIHC cis rs1843834 0.539 rs6739735 chr2:225405253 A/G cg12698349 chr2:225449008 CUL3 -0.68 -10.53 -0.49 1.2e-22 IgE levels in asthmatics (D.p. specific); LIHC cis rs116095464 0.558 rs6878087 chr5:223117 C/T cg22857025 chr5:266934 NA 1.44 17.23 0.68 2.52e-48 Breast cancer; LIHC cis rs10078 0.898 rs2241598 chr5:438564 C/T cg26072250 chr5:443457 EXOC3;C5orf55 -0.47 -6.14 -0.32 2.25e-9 Fat distribution (HIV); LIHC cis rs782590 0.620 rs4322879 chr2:55797033 G/T cg03859395 chr2:55845619 SMEK2 -0.48 -7.75 -0.39 1.05e-13 Metabolic syndrome; LIHC cis rs6088590 0.561 rs2295444 chr20:33173883 C/T cg08999081 chr20:33150536 PIGU 0.68 13.73 0.6 1.72e-34 Coronary artery disease; LIHC cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg11062466 chr8:58055876 NA 0.52 6.83 0.35 3.86e-11 Developmental language disorder (linguistic errors); LIHC cis rs6430585 0.591 rs309118 chr2:136746224 G/C cg07169764 chr2:136633963 MCM6 0.96 14.8 0.62 1.23e-38 Corneal structure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08167039 chr1:762232 NCRNA00115;LOC643837 0.49 7.09 0.36 7.74e-12 Pancreatic cancer; LIHC cis rs9818758 0.607 rs13077498 chr3:49313978 C/T cg00383909 chr3:49044727 WDR6 0.78 6.33 0.32 7.91e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6500602 0.964 rs2896893 chr16:4478559 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.41 6.23 0.32 1.35e-9 Schizophrenia; LIHC cis rs6665290 0.669 rs7552783 chr1:227174145 T/C cg10327440 chr1:227177885 CDC42BPA -1.12 -26.66 -0.82 1.61e-85 Myeloid white cell count; LIHC cis rs2180341 0.824 rs9321076 chr6:127655614 G/A cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.09 -16.38 -0.66 6.14e-45 Gut microbiome composition (summer); LIHC cis rs2880765 0.545 rs17553734 chr15:86013059 C/G cg10818794 chr15:86012489 AKAP13 0.45 6.89 0.35 2.65e-11 Coronary artery disease; LIHC cis rs7647973 1.000 rs2312462 chr3:49601255 A/G cg07636037 chr3:49044803 WDR6 0.5 5.94 0.31 7.18e-9 Menarche (age at onset); LIHC cis rs2191566 0.960 rs7255315 chr19:44510933 A/T cg18700516 chr19:44507157 ZNF230 -0.35 -5.79 -0.3 1.62e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg14893161 chr1:205819251 PM20D1 0.67 9.84 0.47 2.79e-20 Menarche (age at onset); LIHC cis rs2257205 0.667 rs8068677 chr17:56869386 G/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.77 -0.34 5.48e-11 Pancreatic cancer; LIHC cis rs9303401 0.734 rs8073316 chr17:57211381 A/T cg10487724 chr17:56770010 TEX14;RAD51C -0.44 -6.51 -0.33 2.74e-10 Cognitive test performance; LIHC cis rs4713118 0.513 rs149962 chr6:28015918 G/A cg23485639 chr6:28045615 ZNF165 0.38 5.77 0.3 1.75e-8 Parkinson's disease; LIHC cis rs11718455 0.767 rs11130019 chr3:43989348 C/A cg08738300 chr3:44038990 NA 0.51 8.67 0.42 1.71e-16 Coronary artery disease; LIHC cis rs2067615 0.579 rs1073261 chr12:107135942 A/G cg15890332 chr12:107067104 RFX4 0.27 6.34 0.32 7.38e-10 Heart rate; LIHC cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.65 0.38 2e-13 Bipolar disorder; LIHC cis rs67311347 1.000 rs6795475 chr3:40489281 A/G cg00656387 chr3:40428638 ENTPD3 0.42 7.03 0.36 1.13e-11 Renal cell carcinoma; LIHC cis rs10751667 0.666 rs7944815 chr11:959776 C/T cg06064525 chr11:970664 AP2A2 -0.56 -15.02 -0.63 1.64e-39 Alzheimer's disease (late onset); LIHC cis rs2404602 0.684 rs12437981 chr15:76842401 A/G cg03037974 chr15:76606532 NA -0.61 -10.22 -0.48 1.48e-21 Blood metabolite levels; LIHC cis rs12477438 0.520 rs6717729 chr2:99756941 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 21.66 0.76 4.25e-66 Chronic sinus infection; LIHC trans rs6759518 0.557 rs1275529 chr2:27431413 T/C cg01061843 chr6:74171491 MTO1 0.94 6.09 0.31 3.04e-9 Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs589448 0.900 rs588493 chr12:69751986 G/A cg22834771 chr12:69754056 YEATS4 -0.54 -9.55 -0.46 2.62e-19 Cerebrospinal fluid biomarker levels; LIHC cis rs10771431 0.935 rs1117735 chr12:9372728 G/A cg00504896 chr12:9437009 LOC642846 -0.35 -5.88 -0.3 1e-8 Breast size; LIHC cis rs12744310 0.887 rs12028244 chr1:41809162 C/T cg03962019 chr1:41807865 NA 0.39 6.2 0.32 1.65e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs970821 0.667 rs2385507 chr8:124744639 T/C cg00283535 chr8:124749564 ANXA13 0.42 7.7 0.38 1.46e-13 Breast cancer; LIHC cis rs4862750 0.914 rs9995391 chr4:187873749 A/T cg11301795 chr4:187892539 NA 0.26 6.63 0.34 1.3e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7131987 0.903 rs7302129 chr12:29415280 A/T cg14222432 chr12:29376421 FAR2 0.36 6.91 0.35 2.42e-11 QT interval; LIHC cis rs2070488 0.965 rs1046048 chr3:38524742 C/T cg24069376 chr3:38537580 EXOG 0.43 8.0 0.4 1.98e-14 Electrocardiographic conduction measures; LIHC cis rs15676 0.947 rs2759009 chr9:131599008 C/T cg00228799 chr9:131580591 ENDOG 0.44 6.74 0.34 6.67e-11 Blood metabolite levels; LIHC trans rs35110281 0.713 rs6518310 chr21:45098670 T/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.19 0.32 1.76e-9 Mean corpuscular volume; LIHC cis rs13108904 0.905 rs34490749 chr4:1217981 A/G cg02980000 chr4:1222292 CTBP1 -0.54 -7.56 -0.38 3.83e-13 Obesity-related traits; LIHC cis rs2842992 0.830 rs752779 chr6:160133957 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.26 0.55 6.9e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs9527 0.615 rs36045108 chr10:104697929 G/A cg15744005 chr10:104629667 AS3MT -0.29 -5.73 -0.3 2.16e-8 Arsenic metabolism; LIHC cis rs1669338 0.507 rs4685606 chr3:3177973 T/G cg16797762 chr3:3221439 CRBN -0.97 -8.6 -0.42 3e-16 White matter integrity; LIHC cis rs11048434 0.736 rs7302417 chr12:9091116 G/T cg04155231 chr12:9217510 LOC144571 0.32 6.18 0.32 1.78e-9 Sjögren's syndrome; LIHC cis rs7395581 0.918 rs326214 chr11:47298360 G/A cg26139080 chr11:47293733 MADD 0.48 7.99 0.4 2.1e-14 HDL cholesterol; LIHC cis rs8044995 0.563 rs8058517 chr16:68379860 A/G cg03983715 chr16:68378420 PRMT7 0.46 5.95 0.31 6.69e-9 Schizophrenia; LIHC cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg26752003 chr8:145688521 CYHR1 0.61 9.71 0.46 7.77e-20 Age at first birth; LIHC cis rs8077889 0.672 rs4793028 chr17:41857212 T/C cg26893861 chr17:41843967 DUSP3 1.06 18.6 0.71 7.9e-54 Triglycerides; LIHC cis rs9393777 0.513 rs1104871 chr6:26665235 T/G cg12826209 chr6:26865740 GUSBL1 0.55 5.8 0.3 1.48e-8 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg03806693 chr22:41940476 POLR3H -0.96 -11.22 -0.52 4.25e-25 Vitiligo; LIHC cis rs7635838 0.892 rs4684775 chr3:11436413 A/G cg00170343 chr3:11313890 ATG7 0.45 7.04 0.36 1.08e-11 HDL cholesterol; LIHC cis rs4843747 0.573 rs7499959 chr16:88110422 C/G cg06050784 chr16:88016603 BANP 0.34 6.24 0.32 1.27e-9 Menopause (age at onset); LIHC cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 9.19 0.45 3.84e-18 Platelet count; LIHC cis rs920590 0.758 rs7012358 chr8:19662498 C/T cg03894339 chr8:19674705 INTS10 0.6 9.42 0.45 6.86e-19 Acute lymphoblastic leukemia (childhood); LIHC cis rs3736485 0.966 rs2414114 chr15:51905781 T/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.11 -0.31 2.75e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg26338869 chr17:61819248 STRADA 0.61 8.92 0.43 2.9e-17 Prudent dietary pattern; LIHC cis rs787274 1.000 rs4979153 chr9:115554984 G/A cg13803584 chr9:115635662 SNX30 -0.6 -6.68 -0.34 9.69e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs694739 0.894 rs887314 chr11:64053157 T/G cg02228329 chr11:64053129 BAD;GPR137 0.76 10.78 0.5 1.59e-23 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs2637266 0.935 rs2583053 chr10:78402416 A/G cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs9457247 0.588 rs35171809 chr6:167432766 A/G cg12798992 chr6:167411361 FGFR1OP 0.46 7.4 0.37 1.04e-12 Crohn's disease; LIHC cis rs2963155 0.518 rs33389 chr5:142700499 C/T cg17617527 chr5:142782415 NR3C1 0.92 10.62 0.5 5.97e-23 Breast cancer; LIHC cis rs3741404 0.609 rs592271 chr11:63872029 G/T cg18225595 chr11:63971243 STIP1 0.46 7.34 0.37 1.57e-12 Platelet count; LIHC cis rs26868 0.766 rs27556 chr16:2249325 T/C cg02248941 chr16:2239361 CASKIN1 0.35 6.74 0.34 6.95e-11 Height; LIHC cis rs1461503 0.932 rs7107575 chr11:122845406 C/T cg14473756 chr11:122847823 NA 0.33 5.96 0.31 6.22e-9 Menarche (age at onset); LIHC cis rs11098499 0.863 rs13136462 chr4:120543173 C/T cg09307838 chr4:120376055 NA 0.72 10.8 0.5 1.37e-23 Corneal astigmatism; LIHC cis rs473651 0.904 rs472247 chr2:239362573 G/A cg21699342 chr2:239360505 ASB1 0.33 6.25 0.32 1.22e-9 Multiple system atrophy; LIHC cis rs7927592 0.871 rs871212 chr11:68348695 T/A cg16797656 chr11:68205561 LRP5 0.5 7.87 0.39 4.83e-14 Total body bone mineral density; LIHC cis rs7927592 0.513 rs3853616 chr11:68198252 A/G cg16797656 chr11:68205561 LRP5 0.59 10.69 0.5 3.32e-23 Total body bone mineral density; LIHC cis rs11098699 0.821 rs6811630 chr4:124222254 G/A cg09941581 chr4:124220074 SPATA5 0.34 6.79 0.34 4.84e-11 Mosquito bite size; LIHC cis rs992157 0.710 rs56364928 chr2:219059058 G/A cg00012203 chr2:219082015 ARPC2 0.91 16.05 0.66 1.27e-43 Colorectal cancer; LIHC cis rs9473924 0.542 rs13195969 chr6:50814627 C/A cg14470998 chr6:50812995 TFAP2B 0.98 11.12 0.52 9.6e-25 Body mass index; LIHC cis rs7914558 0.902 rs3736922 chr10:104850632 A/G cg04362960 chr10:104952993 NT5C2 -0.4 -5.85 -0.3 1.14e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs75908454 1.000 rs16888050 chr6:169874072 C/T cg19338460 chr6:170058176 WDR27 -0.86 -7.79 -0.39 8.32e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs35110281 0.776 rs9306159 chr21:45061839 G/T cg21573476 chr21:45109991 RRP1B -0.57 -10.89 -0.51 6.8e-24 Mean corpuscular volume; LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.19 0.55 1.29e-28 Height; LIHC trans rs1923243 0.546 rs11210226 chr1:73854284 A/G cg25308542 chr13:92000113 MIR17HG 0.42 6.28 0.32 1.02e-9 Migraine; LIHC cis rs477692 0.648 rs10829603 chr10:131327351 T/G cg05714579 chr10:131428358 MGMT 0.38 6.06 0.31 3.67e-9 Response to temozolomide; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.59 0.56 3.89e-30 Prudent dietary pattern; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg20248075 chr14:71865085 SNORD56B 0.33 6.1 0.31 2.8e-9 Hepatitis; LIHC cis rs4474465 0.736 rs10899542 chr11:78246572 T/G cg27205649 chr11:78285834 NARS2 0.41 6.52 0.33 2.49e-10 Alzheimer's disease (survival time); LIHC cis rs919433 0.963 rs10166569 chr2:198183439 G/A cg10820045 chr2:198174542 NA -0.57 -9.61 -0.46 1.67e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs10159528 0.533 rs2175200 chr10:87368788 C/T cg11737403 chr19:57791287 ZNF460 -0.41 -6.08 -0.31 3.21e-9 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs7617773 0.817 rs6787500 chr3:48299439 T/C cg11946769 chr3:48343235 NME6 0.64 8.73 0.43 1.11e-16 Coronary artery disease; LIHC cis rs1419980 0.673 rs10845432 chr12:7728131 T/C cg25828445 chr12:7781288 NA 0.45 6.82 0.35 4.02e-11 HDL cholesterol levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27613455 chr17:38020644 IKZF3 0.4 6.09 0.31 3.11e-9 Pancreatic cancer; LIHC cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg18306943 chr3:40428807 ENTPD3 0.37 6.47 0.33 3.44e-10 Renal cell carcinoma; LIHC cis rs9399135 0.660 rs9376072 chr6:135280519 G/C cg22676075 chr6:135203613 NA 0.4 6.55 0.33 2.15e-10 Red blood cell count; LIHC trans rs1814175 0.754 rs28663627 chr11:50048829 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs2742417 0.603 rs2742458 chr3:45767602 C/T cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs7617773 0.817 rs9847953 chr3:48282695 A/G cg11946769 chr3:48343235 NME6 0.86 11.08 0.51 1.43e-24 Coronary artery disease; LIHC cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg22974920 chr21:40686053 BRWD1 -0.41 -6.01 -0.31 4.85e-9 Cognitive function; LIHC cis rs2084898 0.943 rs477337 chr11:120000885 T/C cg13907859 chr11:120009124 TRIM29 -0.53 -6.57 -0.33 1.86e-10 Stroke (pediatric); LIHC cis rs4713118 0.513 rs149959 chr6:28013854 T/C cg23485639 chr6:28045615 ZNF165 0.38 5.87 0.3 1.03e-8 Parkinson's disease; LIHC cis rs9326248 1.000 rs7946257 chr11:117053165 A/G cg01368799 chr11:117014884 PAFAH1B2 0.4 5.71 0.3 2.41e-8 Blood protein levels; LIHC cis rs9814567 0.806 rs6806810 chr3:134323522 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.4 -0.45 7.89e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg06238570 chr21:40685208 BRWD1 0.58 6.86 0.35 3.21e-11 Cognitive function; LIHC cis rs6570726 0.791 rs9322029 chr6:145906683 A/G cg23711669 chr6:146136114 FBXO30 0.7 12.03 0.55 4.76e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs62458065 0.513 rs787220 chr7:32581139 C/G cg20159608 chr7:32802032 NA -0.51 -6.1 -0.31 2.89e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs1823913 1.000 rs6704784 chr2:192109558 T/G cg12404831 chr2:192114017 MYO1B -0.34 -6.85 -0.35 3.41e-11 Obesity-related traits; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.18 0.55 1.41e-28 Height; LIHC cis rs4974559 0.895 rs57037487 chr4:1386652 A/G cg05025164 chr4:1340916 KIAA1530 0.48 6.56 0.33 1.97e-10 Systolic blood pressure; LIHC cis rs9300255 0.596 rs1727331 chr12:123718879 C/G cg05973401 chr12:123451056 ABCB9 -0.45 -6.17 -0.32 1.96e-9 Neutrophil percentage of white cells; LIHC cis rs4474465 1.000 rs7950813 chr11:78215082 A/T cg27205649 chr11:78285834 NARS2 0.38 5.81 0.3 1.43e-8 Alzheimer's disease (survival time); LIHC cis rs1059312 1.000 rs7136092 chr12:129280164 G/C cg09035930 chr12:129282057 SLC15A4 0.69 13.29 0.58 8.71e-33 Systemic lupus erythematosus; LIHC cis rs7845219 0.544 rs9643352 chr8:95918288 C/T cg13393036 chr8:95962371 TP53INP1 -0.31 -5.89 -0.3 9.33e-9 Type 2 diabetes; LIHC cis rs7654585 1.000 rs4692025 chr4:25949759 A/C cg10409131 chr4:25915609 C4orf52 -0.42 -6.73 -0.34 7.06e-11 Obesity-related traits; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg10150615 chr22:24372951 LOC391322 -0.56 -8.18 -0.4 5.51e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs769267 0.895 rs2965182 chr19:19548246 A/G cg03709012 chr19:19516395 GATAD2A 1.03 18.46 0.71 2.76e-53 Tonsillectomy; LIHC cis rs3736485 0.966 rs8042289 chr15:51899884 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.29 -0.32 9.87e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12980942 0.872 rs7258749 chr19:41806647 C/T cg25627403 chr19:41769009 HNRNPUL1 0.49 6.18 0.32 1.8e-9 Coronary artery disease; LIHC cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg13409248 chr3:40428643 ENTPD3 0.42 6.73 0.34 7.14e-11 Renal cell carcinoma; LIHC cis rs17125944 0.615 rs2357944 chr14:53305573 T/G cg00686598 chr14:53173677 PSMC6 -0.85 -9.78 -0.47 4.54e-20 Alzheimer's disease (late onset); LIHC cis rs2115536 0.730 rs4573897 chr15:80187225 G/A cg00225070 chr15:80189496 MTHFS 0.59 9.65 0.46 1.16e-19 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg00656387 chr3:40428638 ENTPD3 0.5 8.47 0.42 7.31e-16 Renal cell carcinoma; LIHC cis rs1552244 0.572 rs66514627 chr3:10166632 A/C cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs1003719 0.715 rs1981433 chr21:38542223 T/G cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs1494373 0.543 rs12564479 chr1:220862692 C/A cg06786860 chr1:220876396 NA -0.44 -6.53 -0.33 2.35e-10 Response to antipsychotic therapy (extrapyramidal side effects); LIHC cis rs7520050 0.966 rs1085244 chr1:46563680 C/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.58e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2976388 0.647 rs2585154 chr8:143783485 C/T cg13446199 chr8:143762866 PSCA -0.2 -5.81 -0.3 1.43e-8 Urinary tract infection frequency; LIHC cis rs7618501 0.602 rs2240326 chr3:50128386 G/A cg21467203 chr3:49911342 NA 0.43 7.54 0.38 4.31e-13 Intelligence (multi-trait analysis); LIHC cis rs992157 1.000 rs4791 chr2:219138940 C/T cg00012203 chr2:219082015 ARPC2 0.88 14.23 0.61 2.01e-36 Colorectal cancer; LIHC cis rs10751667 1.000 rs7396366 chr11:986185 C/A ch.11.42038R chr11:967971 AP2A2 0.61 11.3 0.52 2.28e-25 Alzheimer's disease (late onset); LIHC cis rs1023500 0.505 rs134885 chr22:42673811 C/G cg04733989 chr22:42467013 NAGA 0.42 6.29 0.32 9.63e-10 Schizophrenia; LIHC cis rs6500602 0.727 rs4786515 chr16:4578133 T/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 5.96 0.31 6.36e-9 Schizophrenia; LIHC cis rs10791097 0.690 rs12284487 chr11:130729705 T/C cg12179176 chr11:130786555 SNX19 0.74 11.55 0.53 2.87e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4555082 0.794 rs2735827 chr14:105710600 T/A cg13114125 chr14:105738426 BRF1 -0.73 -9.71 -0.46 7.77e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs4660306 1.000 rs7522705 chr1:45992300 C/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.56 7.02 0.35 1.21e-11 Homocysteine levels; LIHC cis rs1707322 0.627 rs3014213 chr1:46045522 T/C cg06784218 chr1:46089804 CCDC17 -0.41 -7.19 -0.36 4.07e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg03264133 chr6:25882463 NA -0.57 -8.26 -0.41 3.13e-15 Blood metabolite levels; LIHC cis rs3845702 0.736 rs12693214 chr2:180825685 G/A cg01881094 chr2:180872142 CWC22 -1.13 -9.96 -0.47 1.12e-20 Schizophrenia; LIHC cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg17691542 chr6:26056736 HIST1H1C -0.43 -5.77 -0.3 1.81e-8 Blood metabolite levels; LIHC cis rs5769765 0.955 rs9616368 chr22:50303533 C/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.85 -10.48 -0.49 1.84e-22 Schizophrenia; LIHC cis rs10540 0.915 rs35389167 chr11:460765 A/G cg03576123 chr11:487126 PTDSS2 -1.18 -9.22 -0.45 3.12e-18 Body mass index; LIHC cis rs10751667 0.666 rs7950967 chr11:955638 G/A cg06064525 chr11:970664 AP2A2 -0.56 -15.03 -0.63 1.52e-39 Alzheimer's disease (late onset); LIHC cis rs13108904 0.905 rs34490749 chr4:1217981 A/G cg19318889 chr4:1322082 MAEA 0.43 6.51 0.33 2.76e-10 Obesity-related traits; LIHC cis rs2404602 0.684 rs3910756 chr15:76945369 C/T cg23625390 chr15:77176239 SCAPER -0.45 -7.16 -0.36 5.01e-12 Blood metabolite levels; LIHC cis rs12701220 0.744 rs2030958 chr7:1076010 G/T cg16145915 chr7:1198662 ZFAND2A -0.32 -6.12 -0.31 2.56e-9 Bronchopulmonary dysplasia; LIHC cis rs911119 0.913 rs6048926 chr20:23580987 C/A cg16589663 chr20:23618590 CST3 0.66 6.9 0.35 2.51e-11 Chronic kidney disease; LIHC cis rs17376456 0.877 rs10050465 chr5:93349963 C/A cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.53e-21 Diabetic retinopathy; LIHC cis rs7572733 0.555 rs35563720 chr2:198923075 A/G cg00792783 chr2:198669748 PLCL1 0.43 6.09 0.31 3e-9 Dermatomyositis; LIHC cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg16325326 chr1:53192061 ZYG11B -0.4 -6.78 -0.34 5.24e-11 Monocyte count; LIHC cis rs1401999 1.000 rs1402002 chr3:183642794 A/G cg01324343 chr3:183735012 ABCC5 0.72 11.82 0.54 2.88e-27 Anterior chamber depth; LIHC cis rs6088590 1.000 rs2236270 chr20:33523155 G/T cg06115741 chr20:33292138 TP53INP2 0.57 7.79 0.39 8.3e-14 Coronary artery disease; LIHC cis rs6754311 0.731 rs12615624 chr2:136721603 A/G cg15123519 chr2:136567270 LCT -0.36 -7.2 -0.36 3.89e-12 Mosquito bite size; LIHC cis rs7572733 0.534 rs1435570 chr2:198731371 T/C cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg04267008 chr7:1944627 MAD1L1 -0.69 -11.45 -0.53 6.37e-26 Bipolar disorder and schizophrenia; LIHC trans rs10761482 0.500 rs2211220 chr10:62271491 A/G cg17314160 chr12:110399253 GIT2 -0.43 -6.59 -0.34 1.68e-10 Schizophrenia; LIHC cis rs1577917 0.958 rs12215265 chr6:86443969 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.21 -0.32 1.52e-9 Response to antipsychotic treatment; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg18173454 chr10:15209775 NMT2 -0.49 -6.16 -0.32 2.03e-9 Facial morphology (factor 20); LIHC cis rs9948 0.786 rs62152783 chr2:97457389 T/A cg01990225 chr2:97406019 LMAN2L -0.73 -6.29 -0.32 9.78e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9326248 0.520 rs74830 chr11:117090558 C/T cg01368799 chr11:117014884 PAFAH1B2 -0.63 -9.56 -0.46 2.44e-19 Blood protein levels; LIHC cis rs2576037 0.526 rs7234570 chr18:44459656 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.73e-12 Personality dimensions; LIHC cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg07424592 chr7:64974309 NA -0.8 -9.23 -0.45 2.94e-18 Diabetic kidney disease; LIHC cis rs5753618 0.509 rs5749229 chr22:31587218 T/C cg22777020 chr22:31556080 RNF185 -0.56 -6.33 -0.32 7.64e-10 Colorectal cancer; LIHC cis rs113352275 1 rs113352275 chr15:78840567 C/T cg24631222 chr15:78858424 CHRNA5 0.41 6.06 0.31 3.53e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs6499255 0.951 rs11641233 chr16:69734563 C/T cg15192750 chr16:69999425 NA 0.43 6.85 0.35 3.53e-11 IgE levels; LIHC cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg18252515 chr7:66147081 NA -1.25 -16.5 -0.67 2.19e-45 Diabetic kidney disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02896705 chr19:18112042 ARRDC2 -0.43 -6.77 -0.34 5.77e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7572733 0.555 rs7561950 chr2:198754244 C/T cg03934865 chr2:198174659 NA 0.45 6.44 0.33 4e-10 Dermatomyositis; LIHC cis rs10883723 0.810 rs13287 chr10:104240438 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.59 0.56 4.07e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs116095464 0.510 rs73016876 chr5:244475 T/C cg22496380 chr5:211416 CCDC127 -1.04 -10.67 -0.5 3.8e-23 Breast cancer; LIHC cis rs926392 0.896 rs742276 chr20:37679849 C/T cg16355469 chr20:37678765 NA 0.39 6.39 0.33 5.57e-10 Dialysis-related mortality; LIHC cis rs7772486 0.875 rs2180192 chr6:146322284 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.7 0.53 7.84e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611519 0.780 rs3171692 chr22:41642212 C/T cg06634786 chr22:41940651 POLR3H -0.5 -5.81 -0.3 1.43e-8 Neuroticism; LIHC cis rs2073300 1.000 rs6048833 chr20:23462185 G/A cg12062639 chr20:23401060 NAPB 0.78 9.81 0.47 3.62e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs12594515 1.000 rs8039974 chr15:45986665 A/G cg01629716 chr15:45996671 NA 0.52 9.47 0.46 4.7e-19 Waist circumference;Weight; LIHC cis rs5769765 0.773 rs9616391 chr22:50314573 C/T cg02269571 chr22:50332266 NA -0.75 -9.95 -0.47 1.19e-20 Schizophrenia; LIHC trans rs7246657 0.943 rs10405064 chr19:37861861 C/T cg10208301 chr11:6592745 DNHD1 0.45 6.06 0.31 3.58e-9 Coronary artery calcification; LIHC trans rs7618501 0.573 rs2624824 chr3:50088266 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.12 -0.44 6.34e-18 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.954 rs1546505 chr4:120241224 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.29 0.45 1.9e-18 Corneal astigmatism; LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg26939375 chr7:64535504 NA 0.44 7.56 0.38 3.63e-13 Calcium levels; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs12893668 0.703 rs7148456 chr14:104028270 C/T cg19000871 chr14:103996768 TRMT61A 0.37 6.32 0.32 8.16e-10 Reticulocyte count; LIHC cis rs4908760 0.613 rs12403640 chr1:8817863 C/T cg20416874 chr1:8611966 RERE -0.58 -10.45 -0.49 2.22e-22 Vitiligo; LIHC cis rs116095464 0.558 rs13354585 chr5:242263 G/C cg22857025 chr5:266934 NA -1.47 -17.87 -0.69 6.8e-51 Breast cancer; LIHC cis rs7845219 0.544 rs10956932 chr8:95948202 C/T cg13393036 chr8:95962371 TP53INP1 0.28 5.95 0.31 6.61e-9 Type 2 diabetes; LIHC cis rs9733 0.744 rs2039590 chr1:150813315 G/A cg13175981 chr1:150552382 MCL1 0.45 6.58 0.34 1.8e-10 Tonsillectomy; LIHC cis rs9457247 1.000 rs444988 chr6:167389674 A/T cg07741184 chr6:167504864 NA 0.3 6.93 0.35 2.14e-11 Crohn's disease; LIHC cis rs1538970 0.816 rs10789464 chr1:45959102 C/T cg24296786 chr1:45957014 TESK2 -0.51 -7.52 -0.38 4.86e-13 Platelet count; LIHC trans rs4566648 0.593 rs10012008 chr4:84183228 A/G cg06219686 chr17:29421884 NF1 -0.53 -6.16 -0.32 2.08e-9 Monocyte count; LIHC cis rs6912958 0.559 rs242270 chr6:88062190 C/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.36 -6.96 -0.35 1.72e-11 Monocyte percentage of white cells; LIHC cis rs2574704 1.000 rs2043576 chr3:11649609 T/C cg15876825 chr3:11651881 VGLL4 -0.48 -8.02 -0.4 1.73e-14 Body mass index; LIHC cis rs10876993 0.928 rs10877008 chr12:58103592 A/G cg18357645 chr12:58087776 OS9 0.51 8.3 0.41 2.43e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg18876405 chr7:65276391 NA -0.54 -9.2 -0.45 3.55e-18 Aortic root size; LIHC cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs208520 0.661 rs1776361 chr6:66822270 G/A cg07460842 chr6:66804631 NA -0.78 -8.59 -0.42 3.14e-16 Exhaled nitric oxide output; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg08733086 chr1:154947035 CKS1B;SHC1 -0.47 -7.09 -0.36 7.91e-12 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7772486 0.790 rs2265474 chr6:146182092 G/A cg23711669 chr6:146136114 FBXO30 0.73 13.28 0.58 9.71e-33 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19138499 chr6:139248115 REPS1 0.27 6.04 0.31 4.12e-9 Cognitive function; LIHC cis rs600806 0.815 rs10858097 chr1:109967324 C/A cg23091122 chr1:110024289 SYPL2 -0.46 -6.09 -0.31 2.96e-9 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg04944784 chr2:26401820 FAM59B -0.72 -9.12 -0.44 6.62e-18 Gut microbiome composition (summer); LIHC cis rs2370759 1.000 rs79442609 chr10:32608749 C/T cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs4362 0.934 rs4335 chr17:61565025 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.37 5.73 0.3 2.2e-8 Blood metabolite levels; LIHC cis rs2845885 0.793 rs56241103 chr11:63882364 C/T cg18375707 chr11:64034959 PLCB3 -0.52 -7.89 -0.39 4.08e-14 Body mass index; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg11062466 chr8:58055876 NA 0.51 7.3 0.37 2.02e-12 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.692 rs1116535 chr15:77009514 C/G cg23625390 chr15:77176239 SCAPER -0.35 -5.8 -0.3 1.55e-8 Blood metabolite levels; LIHC cis rs561341 0.883 rs7219239 chr17:30212016 A/G cg13647721 chr17:30228624 UTP6 -0.74 -7.1 -0.36 7.45e-12 Hip circumference adjusted for BMI; LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg11766577 chr21:47581405 C21orf56 -0.44 -7.37 -0.37 1.31e-12 Testicular germ cell tumor; LIHC trans rs1814175 0.817 rs7924619 chr11:49620632 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.06 -0.78 1.24e-71 Height; LIHC cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg25364880 chr3:44379878 C3orf23 0.53 7.1 0.36 7.12e-12 Depressive symptoms; LIHC trans rs7226229 0.950 rs2291037 chr17:20924523 C/T cg05051152 chr8:124408913 ATAD2 -0.45 -6.21 -0.32 1.55e-9 Blood trace element (Se levels); LIHC cis rs8044868 0.530 rs2288000 chr16:72058881 A/G cg16558253 chr16:72132732 DHX38 -0.36 -5.81 -0.3 1.42e-8 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs523395 0.630 rs616111 chr1:120269991 C/G cg19096424 chr1:120255104 PHGDH -0.64 -8.43 -0.41 9.9e-16 Red blood cell count; LIHC cis rs12479064 0.724 rs10496336 chr2:99996165 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.64 -7.89 -0.39 4.04e-14 Chronic sinus infection; LIHC cis rs7592578 0.508 rs10931451 chr2:191270888 G/A cg10560079 chr2:191398806 TMEM194B -0.72 -10.43 -0.49 2.68e-22 Diastolic blood pressure; LIHC cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg18252515 chr7:66147081 NA -1.22 -16.04 -0.66 1.42e-43 Diabetic kidney disease; LIHC cis rs7116495 1.000 rs2363736 chr11:71656967 T/A cg26138937 chr11:71823887 C11orf51 -0.71 -7.0 -0.35 1.32e-11 Severe influenza A (H1N1) infection; LIHC cis rs760805 1.000 rs4649037 chr1:25258301 G/T cg22509179 chr1:25234806 RUNX3 -0.37 -7.84 -0.39 5.88e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs11122272 0.525 rs2749713 chr1:231537921 T/C cg06096015 chr1:231504339 EGLN1 0.49 9.06 0.44 1.01e-17 Hemoglobin concentration; LIHC cis rs7552404 0.731 rs1493367 chr1:76344011 C/A cg03433033 chr1:76189801 ACADM -0.55 -6.51 -0.33 2.67e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7116495 1.000 rs4338555 chr11:71755696 T/C cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs1401999 0.898 rs6443928 chr3:183729487 C/T cg01324343 chr3:183735012 ABCC5 0.76 12.53 0.56 6.59e-30 Anterior chamber depth; LIHC cis rs4423214 1.000 rs11606631 chr11:71164121 C/A cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs12188164 0.525 rs2561665 chr5:460135 A/G cg26076054 chr5:421317 AHRR 0.27 6.02 0.31 4.54e-9 Cystic fibrosis severity; LIHC cis rs1691799 0.899 rs1168308 chr12:66742183 A/G cg16791601 chr12:66731901 HELB -0.56 -13.79 -0.6 1.05e-34 White blood cell count (basophil); LIHC cis rs7238033 0.624 rs9304321 chr18:43308188 C/T cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs35306767 0.855 rs34318754 chr10:890714 G/A cg26597838 chr10:835615 NA 1.49 17.34 0.68 8.86e-49 Eosinophil percentage of granulocytes; LIHC cis rs2721195 0.654 rs4610795 chr8:145881333 C/T cg12270520 chr8:146023939 ZNF517 -0.37 -5.94 -0.31 7.07e-9 Age at first birth; LIHC cis rs763121 0.853 rs5750673 chr22:39110124 G/A cg06022373 chr22:39101656 GTPBP1 0.63 10.63 0.5 5.27e-23 Menopause (age at onset); LIHC cis rs903552 1.000 rs12908406 chr15:102004046 C/T cg06707286 chr15:102010195 PCSK6 -0.46 -6.57 -0.33 1.91e-10 Diabetic kidney disease; LIHC cis rs12898370 0.651 rs11634056 chr15:77539914 G/A cg17802220 chr15:77601643 NA -0.4 -6.0 -0.31 4.9e-9 Risky sexual behaviors (alcohol dependence interaction); LIHC cis rs1348850 0.914 rs10194648 chr2:178337031 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.86 13.33 0.58 6.33e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.43 0.33 4.18e-10 Bipolar disorder; LIHC cis rs9549367 0.713 rs3024761 chr13:113824090 C/G cg00898013 chr13:113819073 PROZ 0.43 7.12 0.36 6.24e-12 Platelet distribution width; LIHC cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg11062466 chr8:58055876 NA 0.39 5.72 0.3 2.34e-8 Developmental language disorder (linguistic errors); LIHC cis rs68170813 0.605 rs10464620 chr7:107135653 A/G cg02696742 chr7:106810147 HBP1 0.52 5.78 0.3 1.72e-8 Coronary artery disease; LIHC cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs1506636 0.886 rs4731112 chr7:123269118 C/G cg03229431 chr7:123269106 ASB15 -0.61 -12.89 -0.57 2.94e-31 Plateletcrit;Platelet count; LIHC cis rs9457247 0.967 rs447042 chr6:167405435 C/T cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs9513627 1.000 rs7321381 chr13:100126156 G/A cg25919922 chr13:100150906 NA -0.77 -6.95 -0.35 1.82e-11 Obesity-related traits; LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg18306943 chr3:40428807 ENTPD3 0.42 7.19 0.36 4.21e-12 Renal cell carcinoma; LIHC trans rs673253 0.686 rs2819333 chr1:44014573 A/T cg22385623 chr1:145397480 NA -0.39 -6.13 -0.31 2.46e-9 Intelligence (multi-trait analysis); LIHC cis rs12702595 0.643 rs6463663 chr7:7259577 A/G cg04827551 chr7:7268805 C1GALT1 0.33 6.13 0.31 2.48e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs6942756 1.000 rs11769045 chr7:128895335 A/G cg02491457 chr7:128862824 NA -0.73 -11.98 -0.54 7.23e-28 White matter hyperintensity burden; LIHC cis rs4148883 0.603 rs6833176 chr4:100131163 G/C cg12011299 chr4:100065546 ADH4 -0.32 -6.27 -0.32 1.11e-9 Alcohol dependence; LIHC cis rs1552244 0.572 rs58862481 chr3:10164308 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 8.88 0.43 3.79e-17 Alzheimer's disease; LIHC cis rs17854409 0.803 rs3210314 chr20:61472117 C/A cg07645718 chr20:61493192 TCFL5 0.79 6.45 0.33 3.85e-10 Obesity-related traits; LIHC cis rs17253792 0.822 rs28549152 chr14:56091239 A/G cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs477692 1.000 rs477692 chr10:131426022 T/C cg19680672 chr10:131412579 MGMT -0.44 -6.73 -0.34 7.38e-11 Response to temozolomide; LIHC cis rs6912958 0.559 rs107689 chr6:88069333 G/T cg08069147 chr6:88032118 GJB7;C6orf162 0.6 11.49 0.53 4.76e-26 Monocyte percentage of white cells; LIHC cis rs77861329 1.000 rs55664415 chr3:52124885 G/A cg08692210 chr3:52188851 WDR51A 0.82 7.39 0.37 1.17e-12 Macrophage inflammatory protein 1b levels; LIHC cis rs7772486 0.790 rs2253880 chr6:146200774 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.58 0.53 2.23e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9640161 0.659 rs11974980 chr7:150009838 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -7.99 -0.4 2.14e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7296418 0.580 rs78455769 chr12:123856443 G/A cg05973401 chr12:123451056 ABCB9 0.41 6.28 0.32 1.02e-9 Platelet count; LIHC cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg05564831 chr3:52568323 NT5DC2 0.36 5.95 0.31 6.5e-9 Bipolar disorder; LIHC cis rs7945718 0.875 rs9888181 chr11:12782781 G/A cg25843174 chr11:12811716 TEAD1 0.34 7.79 0.39 8.09e-14 Educational attainment (years of education); LIHC trans rs617791 0.678 rs551659 chr11:65749645 C/T cg17712092 chr4:129076599 LARP1B 0.75 12.95 0.57 1.81e-31 Breast cancer; LIHC cis rs17102423 0.594 rs8010213 chr14:65552182 C/T cg16583315 chr14:65563665 MAX -0.4 -8.12 -0.4 8.41e-15 Obesity-related traits; LIHC cis rs589448 0.902 rs315113 chr12:69786543 G/T cg20891283 chr12:69753455 YEATS4 -0.94 -22.79 -0.78 1.45e-70 Cerebrospinal fluid biomarker levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06557630 chr16:49889701 NA 0.39 6.18 0.32 1.79e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg00091569 chr3:40428383 ENTPD3 0.4 6.79 0.34 4.99e-11 Renal cell carcinoma; LIHC cis rs2842992 0.789 rs4276525 chr6:160193612 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.24 0.55 7.91e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs3820068 0.581 rs3940061 chr1:15941276 C/T cg17385448 chr1:15911702 AGMAT 0.35 6.11 0.31 2.64e-9 Systolic blood pressure; LIHC cis rs8062405 0.964 rs11864107 chr16:28885931 T/C cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1008375 0.966 rs28750296 chr4:17685826 A/T cg02297831 chr4:17616191 MED28 0.39 6.24 0.32 1.33e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11690935 0.550 rs55653103 chr2:172861816 T/C cg13550731 chr2:172543902 DYNC1I2 0.45 6.83 0.35 3.98e-11 Schizophrenia; LIHC cis rs79387448 0.655 rs3771167 chr2:102986188 A/G cg09003973 chr2:102972529 NA 1.12 10.52 0.49 1.33e-22 Gut microbiota (bacterial taxa); LIHC cis rs5753037 0.803 rs131262 chr22:30133044 G/T cg01021169 chr22:30184971 ASCC2 -0.32 -5.96 -0.31 6.37e-9 Type 1 diabetes; LIHC cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.68 0.38 1.72e-13 Bipolar disorder; LIHC cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.42 0.37 9.27e-13 Bipolar disorder; LIHC trans rs7618501 0.966 rs2246832 chr3:49881134 A/T cg21659725 chr3:3221576 CRBN 0.97 18.03 0.7 1.51e-51 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07898084 chr13:53029385 CKAP2 0.48 6.78 0.34 5.24e-11 Pancreatic cancer; LIHC cis rs12926788 0.542 rs6497759 chr16:24801737 G/A cg00152838 chr16:24741724 TNRC6A -0.53 -6.57 -0.33 1.91e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs6912958 0.684 rs2787893 chr6:88387359 C/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.43 -7.54 -0.38 4.21e-13 Monocyte percentage of white cells; LIHC cis rs80282103 0.618 rs59377495 chr10:1157019 C/T cg08668510 chr10:1095578 IDI1 0.62 6.02 0.31 4.48e-9 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg09455208 chr3:40491958 NA 0.4 8.25 0.41 3.44e-15 Renal cell carcinoma; LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs3020736 0.500 rs8138678 chr22:42516229 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.26 -0.32 1.18e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs61990749 0.597 rs2112136 chr14:78248952 T/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.65 -0.38 2e-13 Fibroblast growth factor basic levels; LIHC cis rs9911578 0.967 rs8072712 chr17:57162464 A/T cg05425664 chr17:57184151 TRIM37 -0.6 -9.0 -0.44 1.61e-17 Intelligence (multi-trait analysis); LIHC cis rs6723226 0.806 rs6543658 chr2:32718849 G/A cg02381751 chr2:32503542 YIPF4 0.77 11.76 0.54 4.8400000000000004e-27 Intelligence (multi-trait analysis); LIHC cis rs2050392 0.624 rs303436 chr10:30731893 G/T cg25182066 chr10:30743637 MAP3K8 -0.63 -10.36 -0.49 4.59e-22 Inflammatory bowel disease; LIHC cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC trans rs11098499 0.954 rs10034623 chr4:120397829 G/A cg25214090 chr10:38739885 LOC399744 0.57 9.5 0.46 3.7e-19 Corneal astigmatism; LIHC cis rs10463316 0.894 rs10042030 chr5:150768028 T/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.58 -0.34 1.79e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7666738 1.000 rs13124102 chr4:98990696 G/A cg05340658 chr4:99064831 C4orf37 0.68 11.56 0.53 2.64e-26 Colonoscopy-negative controls vs population controls; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15888741 chr10:15139207 RPP38;C10orf111 -0.51 -6.82 -0.35 4.03e-11 Systolic blood pressure; LIHC cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.03 12.86 0.57 3.86e-31 Alzheimer's disease; LIHC cis rs7208859 0.623 rs11658022 chr17:29085359 A/T cg14067834 chr17:29058358 SUZ12P 0.69 6.86 0.35 3.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs7246657 0.943 rs10414904 chr19:37830088 G/A cg10208301 chr11:6592745 DNHD1 0.48 6.96 0.35 1.71e-11 Coronary artery calcification; LIHC cis rs78545713 0.649 rs77727979 chr6:26222026 T/A cg16070018 chr6:26224392 HIST1H3E 0.8 7.54 0.38 4.2e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs6120849 0.754 rs6120793 chr20:33604407 T/C cg24642439 chr20:33292090 TP53INP2 0.65 7.24 0.36 3.02e-12 Protein C levels; LIHC cis rs941873 0.868 rs10740497 chr10:81126380 T/C cg09469691 chr10:81107165 PPIF 0.69 10.42 0.49 2.88e-22 Height; LIHC cis rs12586317 0.547 rs10130773 chr14:35445299 G/A cg05294307 chr14:35346193 BAZ1A -0.47 -6.93 -0.35 2.15e-11 Psoriasis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03379200 chr15:91537914 PRC1 0.47 6.27 0.32 1.11e-9 Lung function (FEV1/FVC); LIHC cis rs7914558 1.000 rs3740387 chr10:104849468 G/A cg15744005 chr10:104629667 AS3MT -0.36 -7.87 -0.39 4.67e-14 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8072100 0.840 rs4968319 chr17:45464967 A/G cg08085267 chr17:45401833 C17orf57 -0.56 -8.49 -0.42 6.2e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6582630 0.555 rs11182148 chr12:38464883 A/C cg26384229 chr12:38710491 ALG10B 0.64 8.84 0.43 4.99e-17 Drug-induced liver injury (flucloxacillin); LIHC trans rs11039798 0.512 rs28453037 chr11:49006929 C/A cg15704280 chr7:45808275 SEPT13 0.57 6.37 0.33 6.13e-10 Axial length; LIHC cis rs12824058 0.831 rs11608407 chr12:130805869 G/A cg26677194 chr12:130822605 PIWIL1 0.5 6.65 0.34 1.16e-10 Menopause (age at onset); LIHC cis rs6502050 0.835 rs3935403 chr17:80114145 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs950776 0.518 rs1979907 chr15:78842239 T/C cg22563815 chr15:78856949 CHRNA5 -0.37 -6.96 -0.35 1.79e-11 Sudden cardiac arrest; LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.659 rs34878689 chr17:56694330 G/A cg10487724 chr17:56770010 TEX14;RAD51C 1.02 13.95 0.6 2.42e-35 Cognitive test performance; LIHC cis rs4319547 0.695 rs11836188 chr12:122865507 T/C cg23029597 chr12:123009494 RSRC2 0.51 7.27 0.37 2.39e-12 Body mass index; LIHC cis rs6754311 0.773 rs666407 chr2:136640233 A/G cg25344623 chr2:136566232 LCT -0.39 -7.83 -0.39 6.24e-14 Mosquito bite size; LIHC cis rs2243480 0.901 rs3813708 chr7:65305632 C/A cg07424592 chr7:64974309 NA 0.81 9.05 0.44 1.13e-17 Diabetic kidney disease; LIHC cis rs400736 0.894 rs172811 chr1:8039949 A/G cg25007680 chr1:8021821 PARK7 0.59 9.33 0.45 1.34e-18 Response to antidepressants and depression; LIHC cis rs1005277 0.602 rs1831315 chr10:38473353 T/C cg00409905 chr10:38381863 ZNF37A -0.57 -9.58 -0.46 2.09e-19 Extrinsic epigenetic age acceleration; LIHC trans rs11098499 0.954 rs10518328 chr4:120401779 G/A cg25214090 chr10:38739885 LOC399744 0.58 9.5 0.46 3.69e-19 Corneal astigmatism; LIHC cis rs72653721 0.838 rs10498676 chr6:11026999 C/T cg13562911 chr6:11044106 ELOVL2 0.48 7.15 0.36 5.22e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs9513627 1.000 rs73556165 chr13:100120317 C/T cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs11711311 1.000 rs9288984 chr3:113525956 A/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.41 7.58 0.38 3.3e-13 IgG glycosylation; LIHC cis rs11958404 0.932 rs6870420 chr5:157437166 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs6430585 0.941 rs12469551 chr2:136510012 T/G cg07169764 chr2:136633963 MCM6 -0.99 -13.97 -0.6 2.17e-35 Corneal structure; LIHC cis rs79839061 0.610 rs62297062 chr4:869698 C/T cg07828340 chr4:882639 GAK 0.85 7.15 0.36 5.17e-12 Intelligence (multi-trait analysis); LIHC cis rs854765 0.647 rs4426402 chr17:17977926 C/T cg04398451 chr17:18023971 MYO15A 0.64 10.26 0.49 1.03e-21 Total body bone mineral density; LIHC cis rs2153535 0.580 rs6918391 chr6:8461178 A/C cg07606381 chr6:8435919 SLC35B3 0.8 11.8 0.54 3.57e-27 Motion sickness; LIHC trans rs3780486 0.846 rs6476402 chr9:33148552 G/A cg04842962 chr6:43655489 MRPS18A 0.97 19.98 0.73 2.22e-59 IgG glycosylation; LIHC cis rs7772486 0.875 rs863820 chr6:146347402 C/T cg23711669 chr6:146136114 FBXO30 -0.68 -12.17 -0.55 1.52e-28 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12040534 chr17:17942854 ATPAF2;C17orf39 0.5 6.94 0.35 1.98e-11 Lung function (FEV1/FVC); LIHC cis rs1707322 0.686 rs3014236 chr1:46091305 T/C cg03146154 chr1:46216737 IPP -0.56 -9.5 -0.46 3.64e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7927771 0.524 rs6485786 chr11:47837408 G/C cg20307385 chr11:47447363 PSMC3 0.75 11.27 0.52 2.82e-25 Subjective well-being; LIHC cis rs909002 0.800 rs1056526 chr1:32084904 C/T cg13919466 chr1:32135498 COL16A1 -0.34 -6.32 -0.32 8.07e-10 Intelligence (multi-trait analysis); LIHC cis rs748404 0.631 rs6493086 chr15:43655394 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.86 0.43 4.31e-17 Lung cancer; LIHC cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg06481639 chr22:41940642 POLR3H -0.72 -6.74 -0.34 6.5500000000000006e-11 Vitiligo; LIHC cis rs12995491 0.902 rs6737641 chr2:88529471 A/T cg04511125 chr2:88470314 THNSL2 -0.42 -6.37 -0.33 6.22e-10 Response to metformin (IC50); LIHC trans rs116095464 0.558 rs7731089 chr5:290422 A/C cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs9300255 0.550 rs10772997 chr12:123719880 C/A cg00376283 chr12:123451042 ABCB9 0.69 10.45 0.49 2.36e-22 Neutrophil percentage of white cells; LIHC cis rs17428076 0.836 rs12622895 chr2:172686304 G/T cg13550731 chr2:172543902 DYNC1I2 -0.38 -6.32 -0.32 8.22e-10 Myopia; LIHC cis rs11644362 0.932 rs34290494 chr16:12987705 A/C cg06890432 chr16:12997467 SHISA9 -0.4 -6.77 -0.34 5.6e-11 Positive affect;Subjective well-being; LIHC cis rs7212590 0.748 rs8074843 chr17:57935935 C/G cg10252138 chr17:58120427 NA -0.64 -6.78 -0.34 5.15e-11 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs6876835 0.553 rs7734641 chr5:6598782 C/T cg04204831 chr5:6583394 LOC255167 0.42 6.44 0.33 3.97e-10 Visceral fat; LIHC trans rs5756813 0.635 rs6000899 chr22:38203796 C/T cg19894588 chr14:64061835 NA -0.68 -10.11 -0.48 3.29e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg18918831 chr3:195489782 MUC4 0.72 11.3 0.52 2.18e-25 Lung disease severity in cystic fibrosis; LIHC cis rs473651 0.967 rs483042 chr2:239335320 A/G cg18131467 chr2:239335373 ASB1 1.09 20.85 0.75 6.7e-63 Multiple system atrophy; LIHC cis rs8103278 0.507 rs2041975 chr19:46238555 T/C cg11657440 chr19:46296263 DMWD 0.68 12.62 0.56 3.16e-30 Coronary artery disease; LIHC cis rs67460515 0.892 rs13059340 chr3:161062631 T/C cg03342759 chr3:160939853 NMD3 -0.58 -8.47 -0.42 7.37e-16 Parkinson's disease; LIHC cis rs265548 0.646 rs36689 chr19:17910639 A/G cg16024904 chr19:17905718 B3GNT3 0.43 6.16 0.32 2.05e-9 Tumor biomarkers; LIHC cis rs2153535 0.580 rs7341201 chr6:8470270 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7613875 0.600 rs2856238 chr3:50158191 C/T cg05623727 chr3:50126028 RBM5 0.34 5.91 0.3 8.06e-9 Body mass index; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08434171 chr17:16284988 UBB -0.45 -6.68 -0.34 9.52e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1865760 0.622 rs10946807 chr6:26079638 T/C cg16482183 chr6:26056742 HIST1H1C 0.47 6.46 0.33 3.5e-10 Height; LIHC cis rs11098499 0.779 rs6815934 chr4:120267310 T/C cg09307838 chr4:120376055 NA 0.63 9.99 0.48 9e-21 Corneal astigmatism; LIHC cis rs317689 0.819 rs317667 chr12:69703754 G/T cg19645103 chr12:69753606 YEATS4 -0.46 -6.3 -0.32 9.14e-10 Response to diuretic therapy; LIHC cis rs6582630 0.555 rs7133706 chr12:38475465 G/A cg13010199 chr12:38710504 ALG10B -0.47 -6.48 -0.33 3.16e-10 Drug-induced liver injury (flucloxacillin); LIHC trans rs116095464 0.558 rs6555056 chr5:226222 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs7616330 0.887 rs1947150 chr3:71113096 A/G cg01511742 chr3:71112437 FOXP1 -0.53 -7.02 -0.36 1.18e-11 QT interval; LIHC cis rs853679 0.517 rs3823180 chr6:28061744 G/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs7927771 0.524 rs12785949 chr11:47729770 C/T cg20307385 chr11:47447363 PSMC3 0.76 11.26 0.52 3.15e-25 Subjective well-being; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg19635926 chr16:89946313 TCF25 0.57 7.64 0.38 2.25e-13 Skin colour saturation; LIHC cis rs7224737 1.000 rs8074708 chr17:40286354 A/G cg00647820 chr17:40259828 DHX58 0.28 5.91 0.3 8.44e-9 Fibrinogen levels; LIHC cis rs4759375 1.000 rs28592032 chr12:123879445 C/T cg00376283 chr12:123451042 ABCB9 0.49 6.29 0.32 9.47e-10 HDL cholesterol; LIHC cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg06640241 chr16:89574553 SPG7 -0.82 -15.43 -0.64 3.95e-41 Multiple myeloma (IgH translocation); LIHC cis rs7116495 1.000 rs642573 chr11:71780854 G/C cg26138937 chr11:71823887 C11orf51 -0.74 -7.3 -0.37 2e-12 Severe influenza A (H1N1) infection; LIHC cis rs9649465 0.967 rs12531955 chr7:123377066 G/A cg03229431 chr7:123269106 ASB15 -0.38 -8.16 -0.4 6.39e-15 Migraine; LIHC cis rs1023500 0.573 rs8135801 chr22:42475568 A/G cg04733989 chr22:42467013 NAGA -0.65 -9.4 -0.45 8.29e-19 Schizophrenia; LIHC cis rs6598955 0.724 rs12068388 chr1:26621596 G/A cg04990556 chr1:26633338 UBXN11 -0.61 -9.97 -0.47 9.83e-21 Obesity-related traits; LIHC cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg07414643 chr4:187882934 NA 0.24 6.14 0.32 2.3e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02196734 chr15:75018032 CYP1A1 0.52 6.87 0.35 3.02e-11 Hepatitis; LIHC cis rs67311347 0.822 rs11709089 chr3:40351484 C/T cg13409248 chr3:40428643 ENTPD3 0.38 5.85 0.3 1.14e-8 Renal cell carcinoma; LIHC cis rs651907 0.514 rs11706494 chr3:101509475 A/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg12463550 chr7:65579703 CRCP 0.67 7.03 0.36 1.15e-11 Diabetic kidney disease; LIHC cis rs2380220 0.640 rs9320386 chr6:95994955 T/C cg04719120 chr6:96025338 MANEA 0.62 6.8 0.35 4.59e-11 Behavioural disinhibition (generation interaction); LIHC cis rs743757 1.000 rs2236987 chr3:50504546 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.53 -7.41 -0.37 9.92e-13 Diastolic blood pressure; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.71 -12.02 -0.54 5.42e-28 Prudent dietary pattern; LIHC cis rs9296092 0.517 rs76361685 chr6:33536458 G/C cg13560919 chr6:33536144 NA -0.41 -6.81 -0.35 4.37e-11 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg11965913 chr1:205819406 PM20D1 0.58 8.51 0.42 5.7e-16 Menarche (age at onset); LIHC cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg11890956 chr21:40555474 PSMG1 1.02 14.54 0.62 1.3e-37 Cognitive function; LIHC trans rs7618501 0.699 rs3733135 chr3:49939587 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.61 9.64 0.46 1.26e-19 Intelligence (multi-trait analysis); LIHC cis rs763121 0.853 rs5757231 chr22:39071658 C/T cg06022373 chr22:39101656 GTPBP1 -0.66 -11.29 -0.52 2.43e-25 Menopause (age at onset); LIHC cis rs2191566 0.639 rs7260075 chr19:44566766 T/C cg20607764 chr19:44506953 ZNF230 -0.37 -6.15 -0.32 2.16e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs116095464 0.558 rs10080225 chr5:232175 A/G cg22496380 chr5:211416 CCDC127 -1.02 -10.51 -0.49 1.47e-22 Breast cancer; LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.54 -7.55 -0.38 3.93e-13 Lymphocyte counts; LIHC cis rs12597458 0.752 rs8051239 chr16:72036257 T/A cg01557791 chr16:72042693 DHODH 0.74 13.32 0.58 6.84e-33 Prostate cancer; LIHC cis rs2580764 0.566 rs2972075 chr2:55292322 T/G cg09592903 chr2:55203963 RTN4 0.61 11.25 0.52 3.45e-25 Mean platelet volume; LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg11070056 chr1:107600091 PRMT6 -0.65 -11.08 -0.51 1.34e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7940866 0.874 rs10894290 chr11:130811049 T/G cg12179176 chr11:130786555 SNX19 0.55 7.93 0.39 3.19e-14 Schizophrenia; LIHC cis rs2180341 0.961 rs7775493 chr6:127615000 C/A cg24812749 chr6:127587940 RNF146 1.07 16.08 0.66 9.77e-44 Breast cancer; LIHC cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg11764359 chr7:65958608 NA 0.58 6.12 0.31 2.54e-9 Diabetic kidney disease; LIHC cis rs4819052 0.851 rs7276103 chr21:46666078 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.67 10.55 0.5 1.04e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12477438 0.765 rs13406288 chr2:99589585 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.5 -0.38 5.49e-13 Chronic sinus infection; LIHC trans rs4376189 0.614 rs12643220 chr4:186635633 G/C cg03610073 chr4:154604770 TLR2 -0.44 -6.1 -0.31 2.91e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs652260 1.000 rs604938 chr19:7903484 A/G cg26014689 chr19:7917955 EVI5L 0.66 11.89 0.54 1.56e-27 Menarche (age at onset); LIHC cis rs214034 0.505 rs6712768 chr2:17932873 G/A cg08383160 chr2:17981519 NA -0.31 -5.75 -0.3 1.95e-8 Response to amphetamines; LIHC cis rs12594515 1.000 rs8032835 chr15:45997897 C/G cg06207120 chr15:45996521 NA 0.31 5.83 0.3 1.27e-8 Waist circumference;Weight; LIHC cis rs6461049 0.646 rs3778970 chr7:2143208 C/A cg02951883 chr7:2050386 MAD1L1 -0.65 -10.72 -0.5 2.67e-23 Schizophrenia; LIHC cis rs16870629 0.564 rs326050 chr5:1002620 C/T cg00278107 chr5:1061253 SLC12A7 0.47 7.17 0.36 4.62e-12 QT interval; LIHC cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs741677 0.663 rs441438 chr17:491006 C/T cg15660573 chr17:549704 VPS53 0.51 8.31 0.41 2.23e-15 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs9326248 0.954 rs521171 chr11:117064693 C/G cg11861562 chr11:117069780 TAGLN 0.48 7.96 0.4 2.5e-14 Blood protein levels; LIHC cis rs1801251 1.000 rs13003675 chr2:233584109 C/T cg08000102 chr2:233561755 GIGYF2 0.77 11.64 0.53 1.34e-26 Coronary artery disease; LIHC cis rs10870270 1.000 rs3935905 chr10:133758262 A/C cg26149184 chr10:133730230 NA 0.46 7.2 0.36 3.97e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.9e-9 Menopause (age at onset); LIHC cis rs6754311 0.597 rs2082729 chr2:136550109 C/T cg15123519 chr2:136567270 LCT 0.45 8.91 0.43 3.02e-17 Mosquito bite size; LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.82 -0.3 1.39e-8 Total body bone mineral density; LIHC cis rs11711311 0.955 rs12630833 chr3:113390883 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.35 -5.89 -0.3 9.4e-9 IgG glycosylation; LIHC cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.18 0.44 4.13e-18 Bipolar disorder; LIHC cis rs4474465 0.736 rs10899550 chr11:78256078 G/A cg27205649 chr11:78285834 NARS2 0.38 5.86 0.3 1.09e-8 Alzheimer's disease (survival time); LIHC cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs11711311 1.000 rs921741 chr3:113444051 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.45 -0.37 7.54e-13 IgG glycosylation; LIHC cis rs2976388 0.590 rs3758082 chr8:143824483 A/G cg06565975 chr8:143823917 SLURP1 -0.42 -7.76 -0.39 1e-13 Urinary tract infection frequency; LIHC cis rs7208859 0.673 rs79541516 chr17:29240583 C/T cg13385521 chr17:29058706 SUZ12P 0.79 7.57 0.38 3.46e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7027203 0.828 rs4744291 chr9:96598297 A/G cg14396892 chr9:96623032 NA -0.33 -6.3 -0.32 9.26e-10 DNA methylation (variation); LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs11588062 1.000 rs11588062 chr1:46779764 C/T cg23431851 chr1:46668822 C1orf190;POMGNT1 0.58 9.41 0.45 7.25e-19 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1018836 0.923 rs6989123 chr8:91551234 A/T cg16814680 chr8:91681699 NA -0.65 -10.52 -0.49 1.28e-22 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg10411590 chr13:21900810 NA 0.42 6.83 0.35 3.88e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs867371 1.000 rs2088858 chr15:82474749 C/T cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.75 -0.34 6.31e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7520050 0.807 rs6671802 chr1:46124663 A/G cg24296786 chr1:45957014 TESK2 -0.39 -5.88 -0.3 9.77e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7660520 0.557 rs76004373 chr4:183731011 C/G cg04181038 chr4:183730758 NA 0.43 5.99 0.31 5.37e-9 Pediatric autoimmune diseases; LIHC cis rs67311347 1.000 rs2168111 chr3:40395325 T/G cg09455208 chr3:40491958 NA 0.33 6.55 0.33 2.06e-10 Renal cell carcinoma; LIHC cis rs1707322 1.000 rs3922887 chr1:46473802 A/G cg03146154 chr1:46216737 IPP 0.47 7.52 0.38 5e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1395 1.000 rs1659685 chr2:27420690 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 0.4 5.81 0.3 1.45e-8 Blood metabolite levels; LIHC cis rs240764 0.604 rs9404016 chr6:101177728 G/A cg09795085 chr6:101329169 ASCC3 0.41 6.05 0.31 3.72e-9 Neuroticism; LIHC cis rs74233809 1.000 rs11191587 chr10:104929716 T/C cg03493300 chr10:104813866 CNNM2 0.46 6.14 0.32 2.29e-9 Birth weight; LIHC cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg24642844 chr7:1081250 C7orf50 -0.94 -9.27 -0.45 2.11e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs1499614 1.000 rs2707830 chr7:66167645 T/C cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC trans rs61931739 0.534 rs1826144 chr12:34094272 A/G cg26384229 chr12:38710491 ALG10B 0.49 6.83 0.35 3.89e-11 Morning vs. evening chronotype; LIHC cis rs34172651 0.517 rs34172679 chr16:24840381 C/T cg00339695 chr16:24857497 SLC5A11 0.74 10.41 0.49 3.04e-22 Intelligence (multi-trait analysis); LIHC cis rs4727027 0.833 rs2107846 chr7:148832774 G/A cg23583168 chr7:148888333 NA -0.74 -10.49 -0.49 1.65e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs72843506 0.586 rs75048432 chr17:19960884 G/A cg12065943 chr17:19881925 AKAP10 -0.33 -6.01 -0.31 4.71e-9 Schizophrenia; LIHC cis rs9513627 1.000 rs7985908 chr13:100186218 T/C cg25919922 chr13:100150906 NA 0.78 7.12 0.36 6.36e-12 Obesity-related traits; LIHC cis rs1577917 0.771 rs2842609 chr6:86296788 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.99 -0.54 6.78e-28 Response to antipsychotic treatment; LIHC cis rs875971 0.767 rs1643394 chr7:65836094 A/G cg18876405 chr7:65276391 NA 0.35 6.38 0.33 5.81e-10 Aortic root size; LIHC cis rs7107174 1.000 rs2510036 chr11:77966788 G/T cg02023728 chr11:77925099 USP35 0.48 9.07 0.44 9.75e-18 Testicular germ cell tumor; LIHC cis rs3796352 1.000 rs13069006 chr3:52973305 G/C cg07884673 chr3:53033167 SFMBT1 0.89 6.49 0.33 3.1e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs4819052 0.851 rs7281263 chr21:46695606 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.24 0.41 3.82e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6976053 0.518 rs144173 chr7:100416250 A/G cg08302003 chr7:100435192 NA -0.39 -6.21 -0.32 1.56e-9 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC trans rs7395662 0.517 rs10454483 chr11:48754997 A/G cg03929089 chr4:120376271 NA -0.43 -6.49 -0.33 3.07e-10 HDL cholesterol; LIHC cis rs8064299 0.597 rs2053748 chr17:72775911 A/G cg25054828 chr17:72772726 NAT9;TMEM104 -0.8 -14.24 -0.61 1.95e-36 Monocyte count; LIHC cis rs921968 0.565 rs12611632 chr2:219621258 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7769051 1.000 rs10484629 chr6:133117870 A/C cg22852734 chr6:133119734 C6orf192 1.0 9.53 0.46 2.98e-19 Type 2 diabetes nephropathy; LIHC trans rs801193 1.000 rs2659906 chr7:66165310 T/C cg26939375 chr7:64535504 NA 0.43 6.84 0.35 3.67e-11 Aortic root size; LIHC cis rs7103648 0.695 rs11039290 chr11:47572279 G/A cg20307385 chr11:47447363 PSMC3 1.02 16.76 0.67 1.93e-46 Diastolic blood pressure;Systolic blood pressure; LIHC trans rs13113518 0.812 rs2048564 chr4:56274132 G/A cg15358633 chr12:38710606 ALG10B 0.44 6.38 0.33 5.68e-10 Height; LIHC cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg11301795 chr4:187892539 NA -0.26 -6.95 -0.35 1.85e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg25897951 chr4:1244024 CTBP1;C4orf42 -0.4 -5.72 -0.3 2.28e-8 Longevity; LIHC cis rs35306767 0.807 rs72778228 chr10:938435 A/G cg20503657 chr10:835505 NA 1.32 14.14 0.61 4.7e-36 Eosinophil percentage of granulocytes; LIHC cis rs16858210 0.874 rs34113436 chr3:183573836 G/A cg25686905 chr3:183603175 PARL -0.51 -9.59 -0.46 1.88e-19 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04260516 chr14:24630327 IRF9 0.42 6.31 0.32 8.45e-10 Pancreatic cancer; LIHC cis rs17270561 0.666 rs1141034 chr6:25780332 C/T cg17691542 chr6:26056736 HIST1H1C 0.41 5.74 0.3 2.13e-8 Iron status biomarkers; LIHC cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg09222892 chr1:25734099 RHCE -0.47 -8.56 -0.42 3.77e-16 Erythrocyte sedimentation rate; LIHC cis rs7520050 0.966 rs4073846 chr1:46462881 C/T cg03146154 chr1:46216737 IPP 0.39 6.44 0.33 4.04e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7917772 0.582 rs4919665 chr10:104366042 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.51 -7.89 -0.39 4.22e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7552404 0.924 rs1694419 chr1:76219801 C/T cg22875332 chr1:76189707 ACADM 0.47 7.39 0.37 1.11e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg21448741 chr8:58168803 NA 0.36 6.72 0.34 7.69e-11 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC cis rs1789 0.903 rs4470622 chr4:15674175 T/G cg24225360 chr4:15471699 CC2D2A -0.37 -5.82 -0.3 1.36e-8 Blood protein levels; LIHC cis rs1075232 0.579 rs58156651 chr15:31749067 C/A cg01030201 chr15:31746330 NA -0.84 -6.85 -0.35 3.41e-11 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs79387448 0.505 rs17027327 chr2:103122513 C/A cg09003973 chr2:102972529 NA 0.82 7.15 0.36 5.19e-12 Gut microbiota (bacterial taxa); LIHC cis rs8177253 1.000 rs8177248 chr3:133479626 C/T cg12373951 chr3:133503437 NA 0.68 11.8 0.54 3.52e-27 Iron status biomarkers; LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg22907277 chr7:1156413 C7orf50 0.54 8.39 0.41 1.26e-15 Longevity;Endometriosis; LIHC cis rs9911578 1.000 rs1267545 chr17:56646909 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.76 0.69 1.81e-50 Intelligence (multi-trait analysis); LIHC trans rs4843747 0.708 rs11866437 chr16:88072279 A/G cg09572067 chr16:29127029 RRN3P2 -0.61 -9.39 -0.45 8.5e-19 Menopause (age at onset); LIHC cis rs2832191 0.647 rs11170 chr21:30378090 C/T cg08807101 chr21:30365312 RNF160 0.78 11.86 0.54 2.04e-27 Dental caries; LIHC cis rs172166 0.694 rs203893 chr6:28062066 C/A cg23485639 chr6:28045615 ZNF165 0.39 6.05 0.31 3.78e-9 Cardiac Troponin-T levels; LIHC cis rs2576037 0.583 rs11659693 chr18:44458733 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -7.09 -0.36 7.75e-12 Personality dimensions; LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg22963979 chr7:1858916 MAD1L1 -0.43 -7.06 -0.36 9.21e-12 Bipolar disorder and schizophrenia; LIHC cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg13944838 chr5:179740914 GFPT2 -0.51 -7.38 -0.37 1.18e-12 Height; LIHC cis rs9814567 1.000 rs13071551 chr3:134310867 C/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.9 0.3 8.68e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1163251 0.869 rs487884 chr1:120217330 C/T cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC cis rs6754311 0.550 rs3213889 chr2:136511575 A/G cg07305463 chr2:136567211 LCT 0.4 7.5 0.38 5.5e-13 Mosquito bite size; LIHC cis rs13108904 0.901 rs4974594 chr4:1300480 C/T cg13395646 chr4:1353034 KIAA1530 0.39 6.17 0.32 1.97e-9 Obesity-related traits; LIHC cis rs8141529 0.509 rs12628211 chr22:29239250 T/C cg15103426 chr22:29168792 CCDC117 0.65 10.46 0.49 2.08e-22 Lymphocyte counts; LIHC cis rs2573652 0.722 rs12914180 chr15:100544416 T/C cg09918751 chr15:100517450 ADAMTS17 -0.69 -12.02 -0.55 5.21e-28 Height; LIHC cis rs7772486 0.754 rs13214277 chr6:146136125 G/T cg05347473 chr6:146136440 FBXO30 0.4 6.36 0.33 6.35e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17376456 0.877 rs9314095 chr5:93425495 T/C cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs7772486 0.875 rs2814869 chr6:146315509 G/A cg23711669 chr6:146136114 FBXO30 0.66 11.51 0.53 3.81e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7312774 0.881 rs1822737 chr12:107309175 A/G cg16260113 chr12:107380972 MTERFD3 0.77 10.12 0.48 3.12e-21 Severe influenza A (H1N1) infection; LIHC cis rs6500602 0.701 rs6500614 chr16:4573938 A/G cg08645402 chr16:4508243 NA 0.4 7.24 0.36 3.06e-12 Schizophrenia; LIHC cis rs4478037 0.643 rs9875798 chr3:33120448 G/C cg16652328 chr3:33138982 GLB1;TMPPE -0.55 -7.04 -0.36 1.03e-11 Major depressive disorder; LIHC cis rs10876993 0.928 rs2640636 chr12:58077544 A/G cg18357645 chr12:58087776 OS9 0.53 8.7 0.43 1.41e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs8108269 0.911 rs10404527 chr19:46160703 G/A cg13320842 chr19:46175254 GIPR 0.43 8.05 0.4 1.37e-14 Type 2 diabetes; LIHC trans rs3749237 0.964 rs11717463 chr3:49808981 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.65 10.22 0.48 1.44e-21 Resting heart rate; LIHC trans rs2727020 0.521 rs2088526 chr11:49531968 G/A cg15704280 chr7:45808275 SEPT13 0.8 11.97 0.54 8.05e-28 Coronary artery disease; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.68 0.62 3.45e-38 Prudent dietary pattern; LIHC cis rs7726839 0.561 rs56410216 chr5:583216 C/A cg09021430 chr5:549028 NA -0.4 -8.48 -0.42 6.68e-16 Obesity-related traits; LIHC cis rs8084351 0.560 rs28718037 chr18:50572697 A/G cg24270629 chr18:50823537 DCC 0.38 5.77 0.3 1.76e-8 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9902453 1.000 rs4239227 chr17:28389103 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs11098499 0.604 rs34278750 chr4:120571136 G/A cg09307838 chr4:120376055 NA 0.66 9.66 0.46 1.12e-19 Corneal astigmatism; LIHC cis rs1198430 0.568 rs1119439 chr1:23828904 A/T cg19827787 chr1:23763612 ASAP3 0.36 5.79 0.3 1.62e-8 Total cholesterol levels; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.49 -0.33 2.94e-10 Total body bone mineral density; LIHC cis rs7312933 0.558 rs55702525 chr12:42814309 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.56 -8.44 -0.42 9.35e-16 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7116495 0.609 rs7113520 chr11:71691946 G/A cg07596299 chr11:71824057 C11orf51 -0.75 -5.72 -0.3 2.3e-8 Severe influenza A (H1N1) infection; LIHC cis rs9300255 0.568 rs1047158 chr12:123644056 C/A cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs875971 0.545 rs3936065 chr7:65790564 C/T cg11764359 chr7:65958608 NA 0.58 8.16 0.4 6.57e-15 Aortic root size; LIHC cis rs4595586 0.525 rs11609150 chr12:39408622 A/C cg26384229 chr12:38710491 ALG10B 0.53 6.35 0.32 6.86e-10 Morning vs. evening chronotype; LIHC cis rs4820294 1.000 rs62236667 chr22:38061520 C/G cg00292662 chr22:38071168 LGALS1 0.64 10.15 0.48 2.48e-21 Fat distribution (HIV); LIHC cis rs1371867 0.875 rs962451 chr8:101331010 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.55e-18 Atrioventricular conduction; LIHC cis rs9733 0.596 rs6686525 chr1:150635811 C/T cg13175981 chr1:150552382 MCL1 -0.43 -5.96 -0.31 6.39e-9 Tonsillectomy; LIHC cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg07424592 chr7:64974309 NA -0.8 -9.32 -0.45 1.44e-18 Diabetic kidney disease; LIHC cis rs1865721 0.804 rs62089468 chr18:73158850 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.28 -0.37 2.28e-12 Intelligence; LIHC cis rs3008870 1.000 rs1118393 chr1:67366668 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.5 0.67 2.13e-45 Lymphocyte percentage of white cells; LIHC cis rs12142240 0.698 rs67142569 chr1:46828460 C/T cg00530320 chr1:46809349 NSUN4 0.53 5.74 0.3 2.12e-8 Menopause (age at onset); LIHC trans rs875971 0.545 rs316328 chr7:65608838 A/G cg26939375 chr7:64535504 NA -0.38 -6.22 -0.32 1.43e-9 Aortic root size; LIHC cis rs7208859 0.562 rs216408 chr17:28907757 C/G cg14067834 chr17:29058358 SUZ12P -0.64 -6.76 -0.34 6.04e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7659604 0.540 rs4455438 chr4:122669550 G/A cg19671926 chr4:122722719 EXOSC9 0.46 6.69 0.34 9.2e-11 Type 2 diabetes; LIHC cis rs1577917 0.654 rs9450284 chr6:86199329 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.54 10.47 0.49 2.03e-22 Response to antipsychotic treatment; LIHC trans rs1941687 0.524 rs6507062 chr18:31374197 G/C cg27147174 chr7:100797783 AP1S1 -0.46 -6.25 -0.32 1.21e-9 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs7100689 0.577 rs10788545 chr10:82034675 A/G cg01528321 chr10:82214614 TSPAN14 0.9 12.01 0.54 5.56e-28 Post bronchodilator FEV1; LIHC trans rs1814175 0.588 rs34449937 chr11:49756013 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.81 0.35 4.37e-11 Height; LIHC cis rs72781680 0.898 rs72796152 chr2:23933626 G/A cg08917208 chr2:24149416 ATAD2B 0.86 7.86 0.39 5.12e-14 Lymphocyte counts; LIHC cis rs763014 1.000 rs7205409 chr16:642610 A/G cg00908189 chr16:619842 PIGQ 0.71 10.59 0.5 7.45e-23 Height; LIHC trans rs1005277 0.579 rs1740745 chr10:38520056 T/C cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs7091068 0.550 rs7901909 chr10:95492508 C/T cg20715218 chr10:95462985 C10orf4 0.59 9.19 0.44 3.96e-18 Urinary tract infection frequency; LIHC cis rs941873 0.805 rs8837 chr10:81114813 C/G cg11057378 chr10:81107060 PPIF 0.37 6.0 0.31 5.15e-9 Height; LIHC cis rs3857067 0.806 rs6858342 chr4:95112318 G/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg00091569 chr3:40428383 ENTPD3 -0.36 -6.12 -0.31 2.62e-9 Renal cell carcinoma; LIHC cis rs2243480 0.706 rs34466769 chr7:65453292 A/C cg18252515 chr7:66147081 NA -0.95 -12.28 -0.55 5.99e-29 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg05590025 chr7:65112418 INTS4L2 -0.62 -6.79 -0.34 4.9e-11 Diabetic kidney disease; LIHC trans rs75804782 0.521 rs56176151 chr2:239440220 T/C cg01134436 chr17:81009848 B3GNTL1 0.71 6.11 0.31 2.75e-9 Morning vs. evening chronotype;Chronotype; LIHC cis rs2180341 1.000 rs6569480 chr6:127621748 A/G cg24812749 chr6:127587940 RNF146 1.07 15.69 0.65 3.58e-42 Breast cancer; LIHC cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.93 0.31 7.61e-9 Height; LIHC cis rs11148252 0.574 rs73186430 chr13:53232891 T/C cg00495681 chr13:53174319 NA 0.72 12.63 0.56 2.89e-30 Lewy body disease; LIHC cis rs7727544 0.636 rs2631365 chr5:131705949 T/C cg24060327 chr5:131705240 SLC22A5 0.59 8.44 0.42 9.07e-16 Blood metabolite levels; LIHC cis rs1062177 0.906 rs2964573 chr5:151160122 A/T cg00977110 chr5:151150581 G3BP1 0.54 6.96 0.35 1.79e-11 Preschool internalizing problems; LIHC cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg01368799 chr11:117014884 PAFAH1B2 0.42 5.87 0.3 1.04e-8 Blood protein levels; LIHC cis rs2075371 0.933 rs432336 chr7:133949064 A/G cg11752832 chr7:134001865 SLC35B4 0.5 7.79 0.39 8.33e-14 Mean platelet volume; LIHC cis rs1008375 1.000 rs11724495 chr4:17621310 G/A cg02297831 chr4:17616191 MED28 0.49 7.6 0.38 2.86e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.49 0.42 6.51e-16 Platelet count; LIHC cis rs10905065 0.829 rs2246399 chr10:5799286 T/A cg11519256 chr10:5708881 ASB13 -0.47 -6.15 -0.32 2.11e-9 Menopause (age at onset); LIHC cis rs2777491 0.915 rs7180418 chr15:41629502 A/C cg18705301 chr15:41695430 NDUFAF1 -0.58 -8.85 -0.43 4.96e-17 Ulcerative colitis; LIHC cis rs5769765 0.908 rs7410318 chr22:50317049 T/C cg09182678 chr22:50328711 NA -0.4 -5.98 -0.31 5.63e-9 Schizophrenia; LIHC cis rs9486719 1.000 rs3906199 chr6:97049899 C/A cg18709589 chr6:96969512 KIAA0776 -0.48 -5.95 -0.31 6.65e-9 Migraine;Coronary artery disease; LIHC cis rs7635838 0.892 rs9836167 chr3:11493392 C/T cg00170343 chr3:11313890 ATG7 0.4 6.33 0.32 7.55e-10 HDL cholesterol; LIHC cis rs17826219 0.561 rs562840 chr17:28949390 G/T cg14067834 chr17:29058358 SUZ12P 0.61 6.36 0.32 6.65e-10 Body mass index; LIHC cis rs6952808 0.531 rs4721441 chr7:2184060 A/G cg21782813 chr7:2030301 MAD1L1 0.33 5.76 0.3 1.9e-8 Bipolar disorder and schizophrenia; LIHC cis rs9443189 0.570 rs523465 chr6:76330434 G/C cg01950844 chr6:76311363 SENP6 0.88 10.98 0.51 3.09e-24 Prostate cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg19687152 chr14:102968497 TECPR2 0.4 6.05 0.31 3.82e-9 Longevity; LIHC cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg21280719 chr6:42927975 GNMT -0.31 -6.98 -0.35 1.49e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs12497850 1.000 rs4858798 chr3:48727112 C/T cg07636037 chr3:49044803 WDR6 0.76 12.67 0.57 2.02e-30 Parkinson's disease; LIHC cis rs858239 0.863 rs274054 chr7:23390467 G/C cg00469287 chr7:23338798 C7orf30 0.49 6.71 0.34 8.02e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs6752107 0.503 rs2304774 chr2:234235749 G/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.44 6.49 0.33 2.95e-10 Crohn's disease;Inflammatory bowel disease; LIHC cis rs3749237 0.595 rs7643845 chr3:49530711 A/G cg02487422 chr3:49467188 NICN1 0.41 6.32 0.32 8.18e-10 Resting heart rate; LIHC trans rs9929218 0.953 rs16260 chr16:68771034 C/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -9.37 -0.45 1.05e-18 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07325041 chr3:17783979 TBC1D5 0.43 6.26 0.32 1.17e-9 Cognitive function; LIHC cis rs8020095 0.571 rs8022328 chr14:67253035 A/G cg03487553 chr14:67822707 ATP6V1D 0.35 6.07 0.31 3.33e-9 Depression (quantitative trait); LIHC cis rs919433 0.750 rs788012 chr2:198229856 A/T cg10820045 chr2:198174542 NA 0.55 8.78 0.43 8.21e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.42 0.45 7.19e-19 Bipolar disorder; LIHC cis rs7587476 0.736 rs62202002 chr2:215690600 T/C cg04004882 chr2:215674386 BARD1 0.57 7.8 0.39 7.33e-14 Neuroblastoma; LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg04267008 chr7:1944627 MAD1L1 -0.69 -11.45 -0.53 6.37e-26 Bipolar disorder and schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09623986 chr2:74753896 AUP1;DQX1 0.42 6.19 0.32 1.68e-9 Longevity; LIHC cis rs2637266 1.000 rs7098790 chr10:78361077 T/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.96e-9 Pulmonary function; LIHC cis rs2645694 0.626 rs2703119 chr4:77823640 C/T cg06046430 chr4:77819534 ANKRD56 0.49 6.55 0.33 2.09e-10 Emphysema distribution in smoking; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14862791 chr5:34839623 TTC23L 0.44 6.36 0.33 6.5e-10 Pancreatic cancer; LIHC cis rs35306767 0.669 rs2101051 chr10:1158791 G/T cg20503657 chr10:835505 NA 0.61 5.88 0.3 9.8e-9 Eosinophil percentage of granulocytes; LIHC cis rs174601 0.615 rs174534 chr11:61549458 C/T cg27386326 chr11:61587980 NA -0.65 -13.1 -0.58 4.78e-32 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs12971120 1.000 rs2278161 chr18:72176083 T/C cg26446133 chr18:72167187 CNDP2 -0.79 -14.73 -0.62 2.25e-38 Refractive error; LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg08469215 chr1:156261351 TMEM79 0.41 6.57 0.33 1.9e-10 Tonsillectomy; LIHC cis rs8141529 0.764 rs5752807 chr22:29223169 A/G cg15103426 chr22:29168792 CCDC117 0.67 11.29 0.52 2.52e-25 Lymphocyte counts; LIHC cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg04546413 chr19:29218101 NA 0.56 10.17 0.48 2.16e-21 Methadone dose in opioid dependence; LIHC cis rs722599 0.748 rs731165 chr14:75352555 T/C cg08847533 chr14:75593920 NEK9 -0.55 -8.87 -0.43 4.2e-17 IgG glycosylation; LIHC cis rs2412488 0.853 rs9996883 chr4:54357177 C/T cg22241045 chr4:54363911 LNX1 0.41 6.55 0.33 2.05e-10 DNA methylation (variation); LIHC cis rs12701220 0.696 rs12112029 chr7:1137889 G/A cg00990874 chr7:1149470 C7orf50 -0.68 -9.8 -0.47 3.73e-20 Bronchopulmonary dysplasia; LIHC cis rs7100689 0.646 rs1340384 chr10:82088702 T/A cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs910316 0.763 rs175450 chr14:75590340 G/A cg08847533 chr14:75593920 NEK9 -0.89 -18.42 -0.71 4.09e-53 Height; LIHC cis rs735396 0.694 rs2264750 chr12:121450165 C/T cg02403541 chr12:121454288 C12orf43 0.52 9.15 0.44 5.08e-18 N-glycan levels; LIHC cis rs16828019 0.929 rs111309254 chr1:41736000 A/G cg20697417 chr1:41786797 NA 0.34 6.53 0.33 2.32e-10 Intelligence (multi-trait analysis); LIHC cis rs4951018 0.526 rs6693913 chr1:205654061 G/C cg17723122 chr1:205641542 SLC45A3 0.43 6.45 0.33 3.89e-10 Prostate-specific antigen levels; LIHC cis rs2439831 0.571 rs689883 chr15:43812596 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.71 11.39 0.52 1.04e-25 Lung cancer in ever smokers; LIHC cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg24642844 chr7:1081250 C7orf50 -0.95 -9.36 -0.45 1.09e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2271001 0.869 rs2042688 chr11:19186294 G/T cg12999362 chr7:75947528 NA -0.36 -6.09 -0.31 3.01e-9 Gut microbiome composition (winter); LIHC cis rs7208859 0.623 rs3752020 chr17:29111125 T/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4759375 1.000 rs61953394 chr12:123753372 T/C cg00376283 chr12:123451042 ABCB9 -0.5 -6.24 -0.32 1.27e-9 HDL cholesterol; LIHC cis rs7917772 0.582 rs12784963 chr10:104336986 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.8 -0.39 7.44e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs477692 0.837 rs543454 chr10:131420536 T/C cg19680672 chr10:131412579 MGMT -0.43 -6.65 -0.34 1.14e-10 Response to temozolomide; LIHC cis rs17685 0.712 rs59659102 chr7:75710114 G/A cg16684958 chr7:75615977 POR 0.51 8.59 0.42 3.18e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4700695 0.697 rs251319 chr5:65239468 A/G cg21114390 chr5:65439923 SFRS12 0.49 6.67 0.34 1.05e-10 Facial morphology (factor 19); LIHC cis rs2286885 1.000 rs10819169 chr9:129249625 C/T cg15282417 chr9:129245246 FAM125B 0.4 6.39 0.33 5.57e-10 Intraocular pressure; LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg06873352 chr17:61820015 STRADA 0.75 13.59 0.59 6.1e-34 Prudent dietary pattern; LIHC cis rs637571 0.544 rs12361552 chr11:65701204 G/A cg02427764 chr11:65769310 BANF1;EIF1AD -0.42 -6.3 -0.32 9.28e-10 Eosinophil percentage of white cells; LIHC cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg10360139 chr7:1886902 MAD1L1 -0.38 -5.74 -0.3 2.04e-8 Bipolar disorder and schizophrenia; LIHC cis rs9733 0.596 rs1136808 chr1:150702717 G/C cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs11098499 0.739 rs4833612 chr4:120147596 A/C cg09307838 chr4:120376055 NA -0.5 -7.64 -0.38 2.17e-13 Corneal astigmatism; LIHC cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -7.93 -0.39 3.22e-14 Type 2 diabetes; LIHC cis rs2979489 0.891 rs2915594 chr8:30401367 T/C cg26383811 chr8:30366931 RBPMS -0.72 -12.03 -0.55 4.82e-28 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs1800795 0.901 rs2069833 chr7:22767664 C/T cg05472934 chr7:22766657 IL6 0.53 8.44 0.42 8.9e-16 Cerebrospinal fluid clusterin levels in APOEe4- carriers; LIHC cis rs3743266 0.507 rs10162677 chr15:60748568 C/T cg22293140 chr15:60689852 ANXA2 -0.64 -6.11 -0.31 2.64e-9 Menarche (age at onset); LIHC cis rs10779751 0.726 rs1205593 chr1:11252716 T/C cg08854313 chr1:11322531 MTOR 0.77 9.86 0.47 2.4e-20 Body mass index; LIHC cis rs926392 0.640 rs2867899 chr20:37694622 C/A cg16355469 chr20:37678765 NA 0.52 7.57 0.38 3.53e-13 Dialysis-related mortality; LIHC cis rs483180 0.512 rs594400 chr1:120214275 G/T cg19096424 chr1:120255104 PHGDH -0.62 -7.86 -0.39 5.01e-14 Macular telangiectasia type 2; LIHC cis rs1419980 0.730 rs11534793 chr12:7752966 G/A cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg05665937 chr4:1216051 CTBP1 0.45 6.08 0.31 3.23e-9 Obesity-related traits; LIHC cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg08219700 chr8:58056026 NA 0.47 6.34 0.32 7.46e-10 Developmental language disorder (linguistic errors); LIHC cis rs77669868 0.929 rs76761091 chr11:114067058 A/G cg01914181 chr11:114070210 ZBTB16 0.65 8.78 0.43 8.24e-17 Monocyte percentage of white cells; LIHC cis rs4803468 0.935 rs13346603 chr19:41945837 T/A cg14132834 chr19:41945861 ATP5SL 0.45 6.57 0.33 1.88e-10 Height; LIHC cis rs17001868 0.568 rs2075764 chr22:40758581 C/T cg07138101 chr22:40742427 ADSL 0.57 6.8 0.35 4.67e-11 Mammographic density (dense area); LIHC cis rs585510 1 rs585510 chr12:121000133 A/G cg27279351 chr12:120934652 DYNLL1 0.67 12.08 0.55 3.21e-28 Reticulocyte fraction of red cells; LIHC cis rs9790314 0.502 rs2404342 chr3:161092562 C/T cg17135325 chr3:160939158 NMD3 0.53 7.55 0.38 4.1e-13 Morning vs. evening chronotype; LIHC cis rs3862030 0.836 rs12771867 chr10:104246691 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.59 -0.38 3e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs55823223 0.702 rs3785437 chr17:73906222 G/T cg23806715 chr17:73775811 H3F3B 0.76 7.08 0.36 8.35e-12 Psoriasis; LIHC cis rs67460515 0.892 rs11718905 chr3:161051793 G/A cg03342759 chr3:160939853 NMD3 -0.62 -9.19 -0.45 3.86e-18 Parkinson's disease; LIHC cis rs8067545 0.641 rs4925060 chr17:19863258 C/G cg13482628 chr17:19912719 NA 0.4 6.63 0.34 1.35e-10 Schizophrenia; LIHC cis rs2404602 0.530 rs12915184 chr15:76965922 G/A cg23625390 chr15:77176239 SCAPER -0.47 -7.41 -0.37 1.03e-12 Blood metabolite levels; LIHC cis rs875971 0.660 rs801190 chr7:66033033 C/T cg00343986 chr7:65444356 GUSB -0.4 -5.99 -0.31 5.42e-9 Aortic root size; LIHC cis rs9926296 0.572 rs8047581 chr16:89884502 C/T cg27121462 chr16:89883253 FANCA 0.47 7.79 0.39 7.98e-14 Vitiligo; LIHC cis rs3018712 0.532 rs2513282 chr11:68418311 A/C cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.12e-8 Total body bone mineral density; LIHC trans rs1864585 0.520 rs7817252 chr8:10685932 C/A cg26278703 chr11:58910052 FAM111A 0.68 6.05 0.31 3.77e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs4665809 0.887 rs4665814 chr2:26273687 G/T cg04944784 chr2:26401820 FAM59B -0.64 -8.17 -0.4 5.85e-15 Gut microbiome composition (summer); LIHC cis rs921968 0.529 rs6729341 chr2:219611434 T/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.38 -0.33 5.68e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg00280220 chr17:61926910 NA 0.42 6.9 0.35 2.56e-11 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs4850891 chr2:99574642 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.76 -11.19 -0.52 5.65e-25 Chronic sinus infection; LIHC cis rs11671005 0.779 rs731259 chr19:58989424 C/T cg25952890 chr19:58913133 NA 0.73 7.45 0.37 7.73e-13 Mean platelet volume; LIHC cis rs4764487 0.687 rs10744702 chr12:6349127 G/A cg08284733 chr12:6341482 CD9 0.38 6.46 0.33 3.61e-10 Mean platelet volume; LIHC cis rs34540877 1.000 rs34552729 chr19:33153320 C/T cg22980127 chr19:33182716 NUDT19 0.86 5.97 0.31 5.84e-9 Red cell distribution width; LIHC cis rs7264396 1.000 rs224434 chr20:34153856 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.9 -0.35 2.5e-11 Total cholesterol levels; LIHC trans rs561341 1.000 rs72821952 chr17:30248133 T/A cg20587970 chr11:113659929 NA -1.39 -11.19 -0.52 5.46e-25 Hip circumference adjusted for BMI; LIHC cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg26818010 chr10:134567672 INPP5A -0.76 -9.44 -0.45 6.06e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9918079 0.560 rs4270584 chr4:15600799 A/G cg24225360 chr4:15471699 CC2D2A 0.4 6.44 0.33 4e-10 Obesity-related traits; LIHC cis rs778371 0.723 rs12993791 chr2:233690082 C/T cg08000102 chr2:233561755 GIGYF2 -0.76 -9.25 -0.45 2.45e-18 Schizophrenia; LIHC cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg00166722 chr3:10149974 C3orf24 0.52 5.99 0.31 5.37e-9 Alzheimer's disease; LIHC trans rs61931739 0.500 rs7977194 chr12:34408459 G/A cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs9303401 0.614 rs56284918 chr17:57178838 A/G cg25039879 chr17:56429692 SUPT4H1 0.77 8.97 0.44 2e-17 Cognitive test performance; LIHC cis rs6001982 0.541 rs733999 chr22:41050335 C/G cg14879645 chr22:41048474 NA 0.4 5.91 0.3 8.13e-9 Breast cancer; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg00061764 chr3:67564432 SUCLG2 0.43 6.2 0.32 1.66e-9 Electroencephalogram traits; LIHC cis rs611744 0.839 rs638238 chr8:109169152 A/G cg18478394 chr8:109455254 TTC35 0.39 6.66 0.34 1.1e-10 Dupuytren's disease; LIHC cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg13395646 chr4:1353034 KIAA1530 -0.59 -8.72 -0.43 1.24e-16 Obesity-related traits; LIHC cis rs919433 0.783 rs3097383 chr2:198236887 A/G cg10820045 chr2:198174542 NA 0.56 8.88 0.43 3.78e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs637571 0.510 rs4930320 chr11:65576788 C/G cg04055107 chr11:65626734 MUS81;CFL1 -0.46 -6.61 -0.34 1.5e-10 Eosinophil percentage of white cells; LIHC cis rs11971779 0.523 rs10234578 chr7:139037988 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg05896524 chr21:47604654 C21orf56 -0.49 -7.77 -0.39 9.17e-14 Testicular germ cell tumor; LIHC cis rs4589502 0.557 rs11071923 chr15:67157715 C/G cg12317470 chr15:67143691 NA 0.53 6.1 0.31 2.8e-9 Lung cancer (smoking interaction); LIHC trans rs12478296 1.000 rs59036157 chr2:243040228 C/A cg01596870 chr19:55963115 NA -0.61 -7.22 -0.36 3.5e-12 Obesity-related traits; LIHC cis rs11055008 0.620 rs2111941 chr12:12829404 A/T cg04607235 chr12:12878440 APOLD1 0.51 7.84 0.39 5.88e-14 Pulse pressure; LIHC cis rs2273669 0.667 rs76747161 chr6:109305456 G/A cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg17554472 chr22:41940697 POLR3H -0.54 -5.76 -0.3 1.84e-8 Vitiligo; LIHC cis rs8060686 0.565 rs8044328 chr16:68146859 G/C cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.69e-8 HDL cholesterol;Metabolic syndrome; LIHC trans rs6952808 0.792 rs2056480 chr7:1954301 A/G cg04565464 chr8:145669602 NFKBIL2 -0.38 -6.04 -0.31 4.04e-9 Bipolar disorder and schizophrenia; LIHC trans rs1499614 1.000 rs2707830 chr7:66167645 T/C cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC trans rs1499614 1.000 rs2659903 chr7:66180931 G/A cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs59698941 0.943 rs55767930 chr5:132203952 G/A cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs933688 1.000 rs61612071 chr5:90741470 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.2 0.66 3.29e-44 Smoking behavior; LIHC cis rs7618501 0.633 rs35065728 chr3:50009176 T/C cg24110177 chr3:50126178 RBM5 -0.46 -7.47 -0.37 6.96e-13 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.717 rs11040450 chr11:49650638 G/A cg15704280 chr7:45808275 SEPT13 -0.99 -20.8 -0.75 1.1e-62 Height; LIHC cis rs8020095 0.571 rs8003929 chr14:67533273 C/G cg03487553 chr14:67822707 ATP6V1D -0.38 -6.55 -0.33 2.12e-10 Depression (quantitative trait); LIHC cis rs66573146 0.572 rs55740475 chr4:6954092 C/G cg15105060 chr4:7024189 TBC1D14 -0.68 -6.1 -0.31 2.88e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2384207 0.818 rs1458366 chr12:113672577 A/G cg22376712 chr12:113623594 C12orf52;DDX54 0.47 5.74 0.3 2.04e-8 Response to fenofibrate (adiponectin levels); LIHC cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.83 7.42 0.37 9.34e-13 Platelet count; LIHC cis rs12477438 0.765 rs6754843 chr2:99680485 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs10464366 0.544 rs6952466 chr7:39155032 A/T cg21665744 chr7:39171113 POU6F2 0.32 5.98 0.31 5.52e-9 IgG glycosylation; LIHC trans rs3783890 0.887 rs2295704 chr14:93814212 T/A cg02802420 chr16:69363236 PDF;COG8 0.33 6.29 0.32 9.92e-10 Body mass index; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg09952564 chr10:5979174 FBXO18 0.51 6.7 0.34 8.34e-11 Hip circumference; LIHC trans rs9747201 1.000 rs9303020 chr17:80163247 C/T cg07393940 chr7:158741817 NA 0.56 6.79 0.34 5.02e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9522267 0.535 rs4644738 chr13:112235995 G/A cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg20476274 chr7:133979776 SLC35B4 0.38 6.09 0.31 3.1e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7769051 1.000 rs3813347 chr6:133119778 G/A cg07930552 chr6:133119739 C6orf192 0.69 6.37 0.33 6.16e-10 Type 2 diabetes nephropathy; LIHC cis rs72627123 0.531 rs3742806 chr14:74532523 A/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.88 8.7 0.43 1.38e-16 Morning vs. evening chronotype; LIHC cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg20887711 chr4:1340912 KIAA1530 0.46 7.08 0.36 8.37e-12 Obesity-related traits; LIHC cis rs782590 0.967 rs1975487 chr2:55809054 A/G cg03859395 chr2:55845619 SMEK2 0.84 14.81 0.63 1.07e-38 Metabolic syndrome; LIHC cis rs9470366 0.509 rs4713996 chr6:36629714 C/T cg08179530 chr6:36648295 CDKN1A -0.56 -8.59 -0.42 3.21e-16 QRS duration; LIHC cis rs9790314 0.905 rs6441370 chr3:160993754 C/T cg03342759 chr3:160939853 NMD3 -0.74 -9.69 -0.46 8.93e-20 Morning vs. evening chronotype; LIHC cis rs1448094 0.512 rs11832992 chr12:86240790 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.28 0.32 1.02e-9 Major depressive disorder; LIHC cis rs12586317 0.620 rs28870452 chr14:35536878 C/A cg16230307 chr14:35515116 FAM177A1 0.8 13.49 0.59 1.47e-33 Psoriasis; LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg21747090 chr2:27597821 SNX17 -0.45 -6.77 -0.34 5.58e-11 Total body bone mineral density; LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg16145915 chr7:1198662 ZFAND2A -0.35 -6.87 -0.35 3.01e-11 Bronchopulmonary dysplasia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23687960 chr8:63951868 GGH 0.42 6.06 0.31 3.65e-9 Cognitive function; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg19487717 chr11:70263216 CTTN 0.43 6.48 0.33 3.12e-10 Immature fraction of reticulocytes; LIHC cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg05555928 chr11:63887634 MACROD1 0.56 7.53 0.38 4.48e-13 Mean platelet volume; LIHC cis rs9457247 0.566 rs10946207 chr6:167456036 C/T cg23791538 chr6:167370224 RNASET2 -0.5 -7.35 -0.37 1.48e-12 Crohn's disease; LIHC cis rs7707921 1.000 rs1019806 chr5:81551659 G/A cg15871215 chr5:81402204 ATG10 0.6 5.89 0.3 9.45e-9 Breast cancer; LIHC cis rs17253792 0.908 rs74354306 chr14:56065778 T/G cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC trans rs35668226 0.891 rs10886850 chr10:122859864 A/C cg08474467 chr16:593365 SOLH 0.38 6.6 0.34 1.6e-10 Type 2 diabetes; LIHC cis rs17685 0.753 rs2868203 chr7:75680026 G/A cg16684958 chr7:75615977 POR -0.51 -8.61 -0.42 2.78e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17376456 1.000 rs56046246 chr5:93531545 T/G cg25358565 chr5:93447407 FAM172A 1.06 9.65 0.46 1.25e-19 Diabetic retinopathy; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg24594292 chr6:111179867 NA 0.61 6.53 0.33 2.32e-10 Mean platelet volume; LIHC cis rs7945718 0.905 rs7124484 chr11:12745271 G/A cg25843174 chr11:12811716 TEAD1 0.36 8.12 0.4 8.38e-15 Educational attainment (years of education); LIHC cis rs3806843 0.657 rs2563283 chr5:140105978 C/A cg16179182 chr5:140090404 VTRNA1-1 0.36 5.87 0.3 1.04e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs11724903 0.935 rs11732243 chr4:183214784 T/C cg16239906 chr20:35724590 RBL1 -0.64 -6.1 -0.31 2.83e-9 Smoking initiation; LIHC cis rs1816752 0.721 rs7399656 chr13:24989846 A/G cg22771759 chr13:24902376 NA 0.3 6.04 0.31 4.1e-9 Obesity-related traits; LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg13409248 chr3:40428643 ENTPD3 0.5 8.35 0.41 1.7e-15 Renal cell carcinoma; LIHC cis rs6088580 0.609 rs6059844 chr20:33036482 A/G cg08999081 chr20:33150536 PIGU 0.66 13.29 0.58 8.65e-33 Glomerular filtration rate (creatinine); LIHC cis rs6912958 0.525 rs59322 chr6:88020521 C/A cg08069147 chr6:88032118 GJB7;C6orf162 0.6 11.08 0.51 1.33e-24 Monocyte percentage of white cells; LIHC cis rs2841277 0.708 rs11623422 chr14:105407031 A/G cg21017887 chr14:105400489 NA 0.66 12.84 0.57 4.6e-31 Rheumatoid arthritis; LIHC trans rs4906332 1.000 rs34479426 chr14:103881823 G/C cg17675199 chr6:35436792 RPL10A 0.31 6.08 0.31 3.13e-9 Coronary artery disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg03320005 chr20:62886973 PCMTD2 -0.4 -6.09 -0.31 3.08e-9 Calcium levels; LIHC cis rs7584330 0.826 rs72620825 chr2:238381243 G/A cg14458575 chr2:238380390 NA 0.52 7.57 0.38 3.51e-13 Prostate cancer; LIHC cis rs875971 1.000 rs709595 chr7:65817333 G/C cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs546131 0.642 rs11603751 chr11:34820809 A/G cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.36 -0.33 6.29e-10 Lung disease severity in cystic fibrosis; LIHC trans rs11098499 0.909 rs28793658 chr4:120307214 A/C cg25214090 chr10:38739885 LOC399744 0.55 8.64 0.42 2.14e-16 Corneal astigmatism; LIHC cis rs7091068 0.522 rs11187621 chr10:95483074 T/C cg20715218 chr10:95462985 C10orf4 0.52 5.97 0.31 6.1e-9 Urinary tract infection frequency; LIHC cis rs7944584 0.588 rs11988 chr11:47261260 G/A cg20307385 chr11:47447363 PSMC3 0.6 6.67 0.34 1.02e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6952808 0.929 rs12699483 chr7:1975624 C/G cg02951883 chr7:2050386 MAD1L1 -0.65 -10.32 -0.49 6.6e-22 Bipolar disorder and schizophrenia; LIHC cis rs9649465 0.934 rs34030532 chr7:123274992 A/G cg03229431 chr7:123269106 ASB15 -0.41 -9.04 -0.44 1.15e-17 Migraine; LIHC cis rs9911578 0.757 rs8081906 chr17:56631907 A/T cg05425664 chr17:57184151 TRIM37 0.47 6.55 0.33 2.1e-10 Intelligence (multi-trait analysis); LIHC cis rs3849570 0.695 rs1851930 chr3:81895318 T/G cg07356753 chr3:81810745 GBE1 -0.49 -7.56 -0.38 3.74e-13 Waist circumference;Body mass index; LIHC cis rs10504229 0.679 rs12375445 chr8:58040082 A/G cg20607798 chr8:58055168 NA 0.46 6.3 0.32 9.07e-10 Developmental language disorder (linguistic errors); LIHC cis rs9368481 0.761 rs4713062 chr6:26948195 A/G cg18867708 chr6:26865862 GUSBL1 -0.54 -8.21 -0.41 4.64e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs7845219 0.506 rs12548999 chr8:95929843 C/T cg13393036 chr8:95962371 TP53INP1 -0.31 -5.95 -0.31 6.8e-9 Type 2 diabetes; LIHC cis rs2303759 0.507 rs35042238 chr19:49872941 C/T cg22307029 chr19:49891270 CCDC155 0.54 5.8 0.3 1.48e-8 Multiple sclerosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20232060 chr3:141457873 RNF7 0.44 6.98 0.35 1.55e-11 Cognitive function; LIHC cis rs7395581 0.797 rs10838681 chr11:47275064 C/T cg26139080 chr11:47293733 MADD -0.48 -7.96 -0.4 2.57e-14 HDL cholesterol; LIHC cis rs3743266 0.507 rs34092508 chr15:60722979 C/T cg22293140 chr15:60689852 ANXA2 -0.64 -6.31 -0.32 8.54e-10 Menarche (age at onset); LIHC cis rs892961 0.932 rs11655686 chr17:75419535 G/A cg01320579 chr17:75405842 SEPT9 0.53 6.9 0.35 2.56e-11 Airflow obstruction; LIHC cis rs12142240 0.698 rs41294456 chr1:46809782 T/C cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC trans rs800082 1.000 rs1961653 chr3:144286098 C/T cg24215973 chr2:240111563 HDAC4 -0.5 -7.31 -0.37 1.93e-12 Smoking behavior; LIHC cis rs1577917 0.682 rs6935918 chr6:86283575 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.21 0.45 3.35e-18 Response to antipsychotic treatment; LIHC cis rs6088813 1.000 rs6088816 chr20:33982435 G/A cg14752227 chr20:34000481 UQCC -0.41 -5.88 -0.3 9.69e-9 Height; LIHC cis rs7187994 0.848 rs16974532 chr16:84783310 G/A cg07647771 chr16:84786436 USP10 -0.33 -6.5 -0.33 2.92e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs317689 0.690 rs317646 chr12:69657145 A/G cg20891283 chr12:69753455 YEATS4 -0.51 -7.38 -0.37 1.19e-12 Response to diuretic therapy; LIHC cis rs5753037 0.745 rs9306465 chr22:30221826 T/A cg01021169 chr22:30184971 ASCC2 -0.35 -6.51 -0.33 2.7e-10 Type 1 diabetes; LIHC cis rs9596863 0.898 rs7984502 chr13:54344640 T/C ch.13.53330881F chr13:54432880 NA 0.45 6.1 0.31 2.94e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs4650994 1.000 rs10913571 chr1:178526648 A/T cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2071426 0.959 rs35427080 chr10:96803649 A/G cg09036531 chr10:96991505 NA -0.51 -6.21 -0.32 1.53e-9 Blood metabolite levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12282830 chr22:29784441 AP1B1 -0.4 -6.17 -0.32 1.96e-9 Longevity; LIHC cis rs7129220 0.588 rs7939064 chr11:10102846 A/C cg01453529 chr11:10209919 SBF2 -0.41 -7.3 -0.37 2.1e-12 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg26338869 chr17:61819248 STRADA -0.59 -8.6 -0.42 2.89e-16 Prudent dietary pattern; LIHC cis rs853679 0.517 rs9393895 chr6:28127621 T/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs6754311 0.773 rs632632 chr2:136638216 A/G cg07169764 chr2:136633963 MCM6 0.7 10.45 0.49 2.37e-22 Mosquito bite size; LIHC cis rs1691799 0.806 rs1168319 chr12:66744857 T/A cg16791601 chr12:66731901 HELB -0.57 -13.96 -0.6 2.36e-35 White blood cell count (basophil); LIHC cis rs2380220 0.872 rs7750757 chr6:95997118 A/G cg15832292 chr6:96025679 MANEA 0.62 7.15 0.36 5.19e-12 Behavioural disinhibition (generation interaction); LIHC cis rs921968 0.643 rs585859 chr2:219383121 C/T cg02985541 chr2:219472218 PLCD4 0.47 8.89 0.43 3.53e-17 Mean corpuscular hemoglobin concentration; LIHC cis rs11758351 0.925 rs2183948 chr6:26180332 A/G cg16070018 chr6:26224392 HIST1H3E 0.58 6.93 0.35 2.09e-11 Gout;Renal underexcretion gout; LIHC trans rs208515 0.525 rs10944871 chr6:66690306 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.86 0.43 4.37e-17 Exhaled nitric oxide levels; LIHC cis rs2236918 0.932 rs2526697 chr1:242040129 A/G cg17736920 chr1:242011382 EXO1 -0.54 -8.41 -0.41 1.11e-15 Menopause (age at onset); LIHC cis rs4642101 0.597 rs9839768 chr3:12821403 C/T cg24848339 chr3:12840334 CAND2 0.31 6.45 0.33 3.92e-10 QRS complex (12-leadsum); LIHC cis rs34172651 0.517 rs2303083 chr16:24835168 G/A cg04756594 chr16:24857601 SLC5A11 0.61 8.45 0.42 8.72e-16 Intelligence (multi-trait analysis); LIHC cis rs9649465 1.000 rs11770041 chr7:123365788 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.15e-15 Migraine; LIHC trans rs6695572 0.697 rs57371116 chr1:77971960 G/T cg04606550 chr5:14226569 TRIO 0.39 6.08 0.31 3.24e-9 Body mass index; LIHC cis rs11212260 0.655 rs78002743 chr11:107324329 C/G cg25435332 chr11:107328525 CWF19L2 0.82 8.43 0.41 9.83e-16 IgG glycosylation; LIHC cis rs600806 0.850 rs11102981 chr1:109967323 G/C cg23091122 chr1:110024289 SYPL2 -0.49 -6.46 -0.33 3.63e-10 Intelligence (multi-trait analysis); LIHC cis rs826838 0.967 rs7136593 chr12:39128265 C/T cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs12908161 1.000 rs11638290 chr15:85227636 C/T cg12863693 chr15:85201151 NMB 0.47 6.73 0.34 7.03e-11 Schizophrenia; LIHC cis rs875971 0.964 rs60193905 chr7:65971260 A/G cg18252515 chr7:66147081 NA -0.43 -6.04 -0.31 4.06e-9 Aortic root size; LIHC trans rs6952808 0.630 rs1860832 chr7:2161849 G/A cg04565464 chr8:145669602 NFKBIL2 0.37 6.2 0.32 1.65e-9 Bipolar disorder and schizophrenia; LIHC cis rs7116495 0.609 rs3016291 chr11:71583482 A/C cg26138937 chr11:71823887 C11orf51 0.69 6.69 0.34 9.16e-11 Severe influenza A (H1N1) infection; LIHC cis rs6964587 0.934 rs35968894 chr7:91762145 A/G cg17063962 chr7:91808500 NA 0.96 14.9 0.63 4.73e-39 Breast cancer; LIHC cis rs425535 0.619 rs7671525 chr4:74792031 C/A cg02530824 chr4:74847766 PF4 -0.38 -5.77 -0.3 1.74e-8 Blood protein levels; LIHC cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg03806693 chr22:41940476 POLR3H 1.05 12.42 0.56 1.73e-29 Vitiligo; LIHC cis rs77633900 0.772 rs157788 chr15:76806011 T/C cg21673338 chr15:77095150 SCAPER -0.53 -6.09 -0.31 3.11e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.13 -16.71 -0.67 3.15e-46 Gut microbiome composition (summer); LIHC cis rs3862030 0.720 rs1056744 chr10:104236687 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.56 -0.38 3.79e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs4555082 0.874 rs11622166 chr14:105759763 C/A cg10792982 chr14:105748885 BRF1 0.46 5.94 0.31 7.16e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs7116495 0.786 rs10736785 chr11:71718912 C/A cg26138937 chr11:71823887 C11orf51 -0.81 -8.16 -0.4 6.65e-15 Severe influenza A (H1N1) infection; LIHC cis rs4975709 0.544 rs4975748 chr5:1866025 G/A cg14773178 chr5:1868261 NA 0.26 6.62 0.34 1.37e-10 Cardiovascular disease risk factors; LIHC trans rs1814175 0.654 rs1164676 chr11:49324868 T/C cg03929089 chr4:120376271 NA 0.75 13.03 0.58 8.69e-32 Height; LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs4742903 0.967 rs3739737 chr9:106858192 A/G cg14250997 chr9:106856677 SMC2 0.43 7.37 0.37 1.32e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs8114671 0.562 rs6120739 chr20:33405227 A/G cg07148914 chr20:33460835 GGT7 0.58 8.7 0.43 1.44e-16 Height; LIHC cis rs2832191 0.791 rs28633762 chr21:30500070 C/T cg24692254 chr21:30365293 RNF160 -0.59 -10.28 -0.49 8.89e-22 Dental caries; LIHC cis rs35110281 0.714 rs2282526 chr21:45080552 A/T cg04455712 chr21:45112962 RRP1B 0.48 7.96 0.4 2.56e-14 Mean corpuscular volume; LIHC cis rs2839186 0.903 rs61182475 chr21:47707050 T/A cg12379764 chr21:47803548 PCNT -0.6 -8.72 -0.43 1.21e-16 Testicular germ cell tumor; LIHC cis rs11671005 0.735 rs11084544 chr19:58940127 C/G cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.22e-13 Mean platelet volume; LIHC cis rs10504229 1.000 rs59797486 chr8:58174435 T/C cg20607798 chr8:58055168 NA 0.48 5.97 0.31 5.95e-9 Developmental language disorder (linguistic errors); LIHC cis rs9457247 1.000 rs9457247 chr6:167392174 C/T cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs7512552 0.839 rs834232 chr1:150354682 T/C cg15654264 chr1:150340011 RPRD2 0.67 11.14 0.52 8.12e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2361718 0.527 rs11150847 chr17:78153130 G/A cg09238746 chr17:78121135 EIF4A3 -0.4 -6.13 -0.31 2.45e-9 Yeast infection; LIHC cis rs11098499 0.863 rs13140391 chr4:120503437 A/G cg09307838 chr4:120376055 NA 0.75 11.88 0.54 1.71e-27 Corneal astigmatism; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19892525 chr11:108157498 ATM -0.43 -6.52 -0.33 2.49e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7044106 0.762 rs7024046 chr9:123419178 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.39 0.52 1.03e-25 Hip circumference adjusted for BMI; LIHC cis rs11190604 0.943 rs3750632 chr10:102279295 G/C cg07080220 chr10:102295463 HIF1AN 0.57 8.26 0.41 3.32e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.23 0.55 8.88e-29 Alzheimer's disease; LIHC cis rs12478296 0.901 rs59191623 chr2:243028595 G/A cg18898632 chr2:242989856 NA -0.45 -6.19 -0.32 1.72e-9 Obesity-related traits; LIHC cis rs7312933 0.618 rs6582390 chr12:42634586 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.79 0.39 7.91e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2991971 0.810 rs2356413 chr1:45914048 A/T cg15605315 chr1:45957053 TESK2 -0.51 -7.26 -0.37 2.58e-12 High light scatter reticulocyte count; LIHC cis rs79149102 0.579 rs58645417 chr15:75325858 T/G cg17294928 chr15:75287854 SCAMP5 -0.49 -6.25 -0.32 1.21e-9 Lung cancer; LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg00914777 chr14:93651123 MOAP1;C14orf109 0.39 6.59 0.34 1.69e-10 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs8016947 0.583 rs12879818 chr14:35830938 G/A cg03549618 chr14:35838977 NA 0.44 6.98 0.35 1.54e-11 Psoriasis; LIHC cis rs8060686 0.516 rs73612297 chr16:68284754 T/G cg05110241 chr16:68378359 PRMT7 -0.54 -6.53 -0.33 2.36e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs2370759 1.000 rs79487858 chr10:32616405 T/C cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs13217239 0.646 rs10946897 chr6:26995251 A/C cg12292205 chr6:26970375 C6orf41 0.44 7.66 0.38 1.99e-13 Schizophrenia; LIHC cis rs240764 0.658 rs11155637 chr6:101203592 A/G cg09795085 chr6:101329169 ASCC3 -0.56 -8.06 -0.4 1.34e-14 Neuroticism; LIHC cis rs882732 1.000 rs10134935 chr14:95037079 T/C cg14866387 chr14:95027382 SERPINA4 -0.42 -6.01 -0.31 4.7e-9 Blood protein levels; LIHC cis rs7772486 0.875 rs1331637 chr6:146337087 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.83 0.54 2.59e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg18876405 chr7:65276391 NA -0.56 -9.52 -0.46 3.24e-19 Calcium levels; LIHC trans rs10411161 0.580 rs12151288 chr19:52381552 A/G cg22319618 chr22:45562946 NUP50 -0.49 -7.27 -0.37 2.47e-12 Breast cancer; LIHC cis rs9325144 0.600 rs6582630 chr12:38743508 A/G cg26384229 chr12:38710491 ALG10B -0.55 -7.75 -0.39 1.08e-13 Morning vs. evening chronotype; LIHC cis rs2645694 0.626 rs904050 chr4:77826089 T/G cg06046430 chr4:77819534 ANKRD56 0.49 6.32 0.32 7.93e-10 Emphysema distribution in smoking; LIHC cis rs12744310 1.000 rs12032756 chr1:41761429 G/A cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs9914544 0.545 rs8068683 chr17:18761827 T/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.8e-10 Educational attainment (years of education); LIHC cis rs9399135 0.967 rs6902954 chr6:135313994 C/A cg24558204 chr6:135376177 HBS1L 0.4 6.58 0.34 1.78e-10 Red blood cell count; LIHC cis rs9611565 0.559 rs5758412 chr22:42080803 T/A cg06634786 chr22:41940651 POLR3H 0.71 7.33 0.37 1.65e-12 Vitiligo; LIHC cis rs116248771 0.739 rs12629635 chr3:158322069 C/T cg16708174 chr3:158430962 RARRES1 0.47 6.08 0.31 3.12e-9 diarrhoeal disease at age 2; LIHC cis rs244293 0.700 rs12939352 chr17:53007655 T/G cg19360675 chr17:53046073 COX11;STXBP4 -0.48 -7.31 -0.37 1.9e-12 Menarche (age at onset); LIHC cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg22963979 chr7:1858916 MAD1L1 -0.41 -6.58 -0.34 1.74e-10 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs922107 0.713 rs2061478 chr1:90044453 G/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.73 -0.39 1.19e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs2303759 0.543 rs7255778 chr19:49906608 G/A cg22590775 chr19:49891494 CCDC155 0.47 7.76 0.39 9.85e-14 Multiple sclerosis; LIHC cis rs644799 1.000 rs557079 chr11:95530125 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.82 0.47 3.16e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9378688 0.654 rs2505659 chr6:2326637 G/A cg12303981 chr6:2244766 GMDS -0.45 -6.06 -0.31 3.59e-9 Caudate nucleus volume; LIHC cis rs4803468 1.000 rs166925 chr19:41926098 T/C cg14132834 chr19:41945861 ATP5SL -0.46 -6.78 -0.34 5.36e-11 Height; LIHC cis rs28735056 1.000 rs4798923 chr18:77629373 G/A cg20368463 chr18:77673604 PQLC1 -0.38 -6.64 -0.34 1.21e-10 Schizophrenia; LIHC cis rs7666738 0.830 rs7673880 chr4:99057262 A/G cg05340658 chr4:99064831 C4orf37 0.71 12.89 0.57 2.92e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs225245 0.755 rs6505493 chr17:34028901 A/G cg05299278 chr17:33885742 SLFN14 0.23 6.2 0.32 1.66e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs4474465 0.920 rs7947824 chr11:78223731 C/G cg02023728 chr11:77925099 USP35 -0.36 -6.22 -0.32 1.43e-9 Alzheimer's disease (survival time); LIHC cis rs4718428 0.672 rs4718412 chr7:66286867 C/T cg18252515 chr7:66147081 NA 0.7 9.46 0.46 5.05e-19 Corneal structure; LIHC cis rs11098499 0.954 rs4577559 chr4:120404043 T/G cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.65e-29 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg17178900 chr1:205818956 PM20D1 -0.66 -9.81 -0.47 3.55e-20 Menarche (age at onset); LIHC trans rs6952808 0.692 rs60755037 chr7:2030104 G/A cg04565464 chr8:145669602 NFKBIL2 0.4 6.69 0.34 9.34e-11 Bipolar disorder and schizophrenia; LIHC cis rs4908768 0.906 rs11121223 chr1:8772845 T/A cg20416874 chr1:8611966 RERE 0.55 7.86 0.39 4.97e-14 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3862030 0.720 rs3740415 chr10:104232716 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.27 -0.37 2.42e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs7116495 1.000 rs3018301 chr11:71792071 A/G cg26138937 chr11:71823887 C11orf51 -0.64 -6.55 -0.33 2.09e-10 Severe influenza A (H1N1) infection; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01287788 chr2:86362935 SNORD94;PTCD3 -0.69 -10.76 -0.5 1.94e-23 Lung function (FEV1/FVC); LIHC cis rs151997 0.671 rs27845 chr5:50197420 A/C cg06027927 chr5:50259733 NA 0.44 6.53 0.33 2.38e-10 Callous-unemotional behaviour; LIHC cis rs6952808 0.771 rs10275045 chr7:1920826 C/T cg14004847 chr7:1930337 MAD1L1 -0.51 -7.49 -0.38 5.99e-13 Bipolar disorder and schizophrenia; LIHC cis rs2576037 0.796 rs2576038 chr18:44582200 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.17 -0.36 4.67e-12 Personality dimensions; LIHC cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg11644478 chr21:40555479 PSMG1 0.79 9.9 0.47 1.7e-20 Cognitive function; LIHC cis rs9814567 1.000 rs4572812 chr3:134291177 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.25 0.55 7.29e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9814567 1.000 rs9834755 chr3:134206845 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.39 -0.56 2.33e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7551222 0.752 rs6594016 chr1:204539462 G/A cg20240347 chr1:204465584 NA -0.36 -7.6 -0.38 2.88e-13 Schizophrenia; LIHC trans rs637571 0.522 rs528736 chr11:65705108 A/G cg17712092 chr4:129076599 LARP1B 0.75 13.15 0.58 2.93e-32 Eosinophil percentage of white cells; LIHC cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg13397359 chr6:42928475 GNMT 0.64 9.29 0.45 1.79e-18 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3917254 0.570 rs2310187 chr2:102750428 G/T cg22835712 chr2:102737379 NA -0.52 -6.51 -0.33 2.69e-10 Blood protein levels; LIHC cis rs26868 0.766 rs27556 chr16:2249325 T/C cg25665528 chr16:2260870 C16orf79 -0.36 -6.32 -0.32 8.36e-10 Height; LIHC cis rs12530845 0.673 rs73725437 chr7:135327853 G/A cg23117316 chr7:135346802 PL-5283 -0.4 -5.98 -0.31 5.7e-9 Red blood cell traits; LIHC cis rs611744 0.647 rs1448150 chr8:109276161 T/C cg18478394 chr8:109455254 TTC35 0.43 7.48 0.37 6.5e-13 Dupuytren's disease; LIHC cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.28 -5.82 -0.3 1.33e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs6690583 0.623 rs1371140 chr1:85455362 A/C cg22153463 chr1:85462885 MCOLN2 0.49 5.91 0.3 8.45e-9 Serum sulfate level; LIHC cis rs2576037 0.583 rs512699 chr18:44374681 C/T cg19077165 chr18:44547161 KATNAL2 0.45 6.85 0.35 3.46e-11 Personality dimensions; LIHC cis rs763121 0.853 rs6001214 chr22:39149155 C/T cg06544989 chr22:39130855 UNC84B 0.38 5.95 0.31 6.62e-9 Menopause (age at onset); LIHC cis rs8180040 0.966 rs7649234 chr3:47494380 G/C cg27129171 chr3:47204927 SETD2 0.57 9.82 0.47 3.27e-20 Colorectal cancer; LIHC cis rs7178375 1.000 rs28881289 chr15:31223955 A/G cg19680485 chr15:31195859 MTMR15 -0.53 -5.85 -0.3 1.12e-8 Hypertriglyceridemia; LIHC trans rs11689435 0.925 rs2373065 chr2:218351628 C/T cg13544946 chr9:35729779 TLN1 -0.41 -6.1 -0.31 2.82e-9 Metabolite levels (MHPG); LIHC cis rs1292059 1 rs1292059 chr17:57957888 T/A cg13753209 chr17:57696993 CLTC 0.69 10.29 0.49 8.02e-22 Eosinophil percentage of granulocytes; LIHC cis rs7089973 0.604 rs7919649 chr10:116609576 T/C cg23260525 chr10:116636907 FAM160B1 0.35 6.98 0.35 1.52e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs597539 0.652 rs557625 chr11:68634722 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.02e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6904897 0.538 rs4639353 chr6:135224328 A/G cg24558204 chr6:135376177 HBS1L -0.42 -6.86 -0.35 3.21e-11 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs11077998 0.723 rs3829566 chr17:80528996 C/T cg11779900 chr17:80519722 FOXK2 -0.39 -5.79 -0.3 1.56e-8 Reticulocyte fraction of red cells; LIHC cis rs933688 0.877 rs1477349 chr5:90707773 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.7 0.73 2.92e-58 Smoking behavior; LIHC cis rs5769765 0.862 rs9616392 chr22:50314705 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.87 -10.78 -0.5 1.56e-23 Schizophrenia; LIHC cis rs7917772 0.636 rs2482499 chr10:104516246 G/A cg22532475 chr10:104410764 TRIM8 -0.36 -6.32 -0.32 8.36e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg17747265 chr1:1875780 NA -0.59 -11.47 -0.53 5.62e-26 Body mass index; LIHC trans rs17685 0.712 rs11764119 chr7:75812358 T/G cg19862616 chr7:65841803 NCRNA00174 0.9 18.39 0.71 5.07e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3762637 0.943 rs9822345 chr3:122245598 A/G cg24169773 chr3:122142474 KPNA1 -0.46 -9.0 -0.44 1.54e-17 LDL cholesterol levels; LIHC cis rs7089973 0.604 rs7095816 chr10:116585109 T/C cg23260525 chr10:116636907 FAM160B1 0.39 7.63 0.38 2.32e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg10295955 chr4:187884368 NA -0.98 -23.24 -0.78 2.31e-72 Lobe attachment (rater-scored or self-reported); LIHC cis rs7615952 0.641 rs7640158 chr3:125808011 G/A cg05084668 chr3:125655381 ALG1L -0.39 -5.99 -0.31 5.24e-9 Blood pressure (smoking interaction); LIHC cis rs2806561 0.780 rs6650086 chr1:23338384 T/C cg19743168 chr1:23544995 NA -0.37 -6.9 -0.35 2.58e-11 Height; LIHC trans rs6952808 0.723 rs1107592 chr7:2041432 C/T cg04565464 chr8:145669602 NFKBIL2 -0.37 -6.28 -0.32 1.01e-9 Bipolar disorder and schizophrenia; LIHC cis rs921968 0.643 rs6708683 chr2:219504503 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.08 0.31 3.18e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg16405210 chr4:1374714 KIAA1530 0.42 6.27 0.32 1.1e-9 Obesity-related traits; LIHC trans rs4566357 0.615 rs10177528 chr2:227913706 G/A cg16088116 chr21:44841560 SIK1 -0.4 -6.22 -0.32 1.42e-9 Coronary artery disease; LIHC cis rs3762637 1.000 rs7626861 chr3:122155196 T/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs2153535 0.580 rs2327057 chr6:8443319 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.89 0.39 4.23e-14 Motion sickness; LIHC cis rs1419980 0.722 rs752452 chr12:7781021 G/A cg10578777 chr12:7781093 NA 0.5 8.9 0.43 3.27e-17 HDL cholesterol levels; LIHC cis rs6964587 1.000 rs9691325 chr7:91731047 G/A cg17063962 chr7:91808500 NA 1.0 18.58 0.71 8.76e-54 Breast cancer; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22929808 chr12:58027113 B4GALNT1 0.45 6.22 0.32 1.42e-9 Pancreatic cancer; LIHC cis rs11112613 0.713 rs12580741 chr12:105941328 A/G cg03607813 chr12:105948248 NA -0.61 -11.76 -0.54 5.01e-27 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs8062405 1.000 rs12443881 chr16:28841777 C/T cg16576597 chr16:28551801 NUPR1 0.37 5.95 0.31 6.7e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8072100 1.000 rs8072100 chr17:45674687 A/T cg15066416 chr17:45501628 LOC100272146;C17orf57 0.36 5.81 0.3 1.4e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1865760 1.000 rs7757666 chr6:25902626 T/C cg17691542 chr6:26056736 HIST1H1C 0.39 5.91 0.3 8.47e-9 Height; LIHC cis rs2637266 0.716 rs2579734 chr10:78441306 A/G cg18941641 chr10:78392320 NA 0.27 5.85 0.3 1.13e-8 Pulmonary function; LIHC cis rs2050392 0.771 rs303446 chr10:30728489 C/T cg25182066 chr10:30743637 MAP3K8 -0.48 -7.93 -0.39 3.23e-14 Inflammatory bowel disease; LIHC cis rs11628318 0.614 rs11847932 chr14:103185435 T/G cg12046867 chr14:103022105 NA 0.51 7.11 0.36 6.88e-12 Platelet count; LIHC cis rs7523273 0.565 rs2025374 chr1:207887536 A/G cg22525895 chr1:207977042 MIR29B2 -0.5 -7.79 -0.39 8.07e-14 Schizophrenia; LIHC cis rs9318086 0.935 rs9652081 chr13:24435510 C/T cg25267304 chr13:24462978 PCOTH;MIPEP -0.54 -10.79 -0.5 1.45e-23 Myopia (pathological); LIHC cis rs644799 0.635 rs10831428 chr11:95508404 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.78 13.29 0.58 8.97e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7619427 0.908 rs62253229 chr3:44080221 G/A cg24966902 chr3:44043705 NA 0.43 6.19 0.32 1.69e-9 Schizophrenia; LIHC cis rs11098699 1.000 rs7663175 chr4:124175909 G/T cg09941581 chr4:124220074 SPATA5 0.34 6.35 0.32 6.66e-10 Mosquito bite size; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03729566 chr7:1059678 C7orf50 0.39 6.07 0.31 3.43e-9 Longevity; LIHC cis rs875971 0.830 rs28714531 chr7:65968237 G/A cg11764359 chr7:65958608 NA 0.78 13.52 0.59 1.17e-33 Aortic root size; LIHC cis rs7937890 1.000 rs6486190 chr11:14401216 A/C cg02251663 chr11:14281053 SPON1 -0.43 -5.99 -0.31 5.36e-9 Mitochondrial DNA levels; LIHC cis rs4716602 0.596 rs12386632 chr7:156158221 G/A cg16983916 chr7:156159713 NA -0.32 -5.84 -0.3 1.22e-8 Anti-saccade response; LIHC cis rs1005277 0.579 rs1780130 chr10:38485378 T/A cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.2 -0.32 1.6e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8017423 0.967 rs8021881 chr14:90722276 T/C cg14092571 chr14:90743983 NA -0.38 -6.03 -0.31 4.15e-9 Mortality in heart failure; LIHC cis rs611744 0.846 rs405534 chr8:109154408 T/A cg18478394 chr8:109455254 TTC35 0.34 5.81 0.3 1.44e-8 Dupuytren's disease; LIHC cis rs5769765 0.542 rs761878 chr22:50249677 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.61 5.97 0.31 6.04e-9 Schizophrenia; LIHC trans rs9929218 0.954 rs112225541 chr16:68755165 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -9.07 -0.44 9.69e-18 Colorectal cancer; LIHC cis rs12701220 0.522 rs12334290 chr7:1054517 A/G cg04025307 chr7:1156635 C7orf50 0.48 6.89 0.35 2.75e-11 Bronchopulmonary dysplasia; LIHC cis rs6815814 0.950 rs4540055 chr4:38803255 A/T cg06935464 chr4:38784597 TLR10 0.4 6.31 0.32 8.86e-10 Breast cancer; LIHC cis rs13191362 0.935 rs7767254 chr6:162954674 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.89 0.3 9.29e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2073300 1.000 rs6036411 chr20:23441706 A/C cg16736954 chr20:23401023 NAPB 0.52 5.89 0.3 9.2e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs11724903 1.000 rs17072957 chr4:183201342 A/G cg16239906 chr20:35724590 RBL1 0.61 6.22 0.32 1.48e-9 Smoking initiation; LIHC cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg17372223 chr3:52568218 NT5DC2 0.36 5.97 0.31 5.98e-9 Bipolar disorder; LIHC cis rs4407350 0.721 rs131156 chr22:44891370 T/C cg11695653 chr22:44894386 LDOC1L -0.37 -6.36 -0.33 6.35e-10 Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20601684 chr10:27792608 RAB18 0.55 6.89 0.35 2.63e-11 Systolic blood pressure; LIHC cis rs4728302 0.869 rs6963032 chr7:133599527 T/C cg10665199 chr7:133106180 EXOC4 0.38 6.69 0.34 9.03e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs797680 0.786 rs9432465 chr1:93780591 G/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.04 -0.31 3.95e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs8017423 0.967 rs6575117 chr14:90715412 G/A cg04374321 chr14:90722782 PSMC1 0.74 14.52 0.62 1.51e-37 Mortality in heart failure; LIHC cis rs7937682 0.575 rs11604704 chr11:111764396 G/A cg09085632 chr11:111637200 PPP2R1B 0.94 13.48 0.59 1.64e-33 Primary sclerosing cholangitis; LIHC cis rs11711311 1.000 rs2603789 chr3:113470479 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.25 -0.37 2.72e-12 IgG glycosylation; LIHC cis rs2224391 1.000 rs2773320 chr6:5261681 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.41 -6.13 -0.31 2.46e-9 Height; LIHC cis rs2834188 1.000 rs2252931 chr21:34704320 A/G cg14352951 chr21:34696688 IFNAR1 0.44 5.77 0.3 1.77e-8 Narcolepsy; LIHC cis rs67460515 0.500 rs6806015 chr3:160724766 G/A cg17135325 chr3:160939158 NMD3 0.42 5.73 0.3 2.21e-8 Parkinson's disease; LIHC cis rs829883 0.664 rs249833 chr12:98832189 T/C cg25150519 chr12:98850993 NA 0.68 10.72 0.5 2.59e-23 Colorectal adenoma (advanced); LIHC cis rs12701220 0.655 rs7784403 chr7:1153077 G/A cg00990874 chr7:1149470 C7orf50 -0.7 -9.78 -0.47 4.49e-20 Bronchopulmonary dysplasia; LIHC cis rs7412746 0.658 rs2230061 chr1:150727539 G/A cg17724175 chr1:150552817 MCL1 0.49 9.58 0.46 2.01e-19 Melanoma; LIHC cis rs739401 0.572 rs389285 chr11:3062673 G/A cg20651018 chr11:3035856 CARS -0.37 -6.21 -0.32 1.52e-9 Longevity; LIHC cis rs7829975 0.617 rs4841072 chr8:8791253 C/A cg06636001 chr8:8085503 FLJ10661 -0.4 -6.35 -0.32 6.82e-10 Mood instability; LIHC cis rs853679 0.517 rs9380057 chr6:28104634 G/T cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs7267979 0.565 rs4815432 chr20:25556403 A/C cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.27 -0.32 1.12e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2806561 0.704 rs674386 chr1:23521835 G/A cg19743168 chr1:23544995 NA 0.38 6.27 0.32 1.07e-9 Height; LIHC cis rs3540 0.574 rs2657947 chr15:90968977 C/T cg22089800 chr15:90895588 ZNF774 -0.54 -7.44 -0.37 7.95e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs4713118 0.869 rs9295742 chr6:27702832 G/A cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs17106184 1.000 rs72902767 chr1:51260999 A/G cg07174182 chr1:51127561 FAF1 -0.64 -6.93 -0.35 2.12e-11 Type 2 diabetes; LIHC cis rs3806933 0.522 rs13157863 chr5:110470505 G/A cg04022379 chr5:110408740 TSLP 0.55 8.49 0.42 6.41e-16 Eosinophilic esophagitis; LIHC cis rs67460515 0.529 rs6795586 chr3:160897701 A/C cg03342759 chr3:160939853 NMD3 -0.49 -7.05 -0.36 9.72e-12 Parkinson's disease; LIHC cis rs5769765 1.000 rs4824106 chr22:50267822 T/C cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs10791323 0.572 rs10791334 chr11:133735810 A/C cg06766960 chr11:133703094 NA -0.49 -7.63 -0.38 2.3e-13 Childhood ear infection; LIHC cis rs1348850 0.632 rs4470372 chr2:178505857 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.9 0.39 3.83e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12701220 0.817 rs1058727 chr7:1087095 A/G cg16145915 chr7:1198662 ZFAND2A -0.3 -5.99 -0.31 5.28e-9 Bronchopulmonary dysplasia; LIHC cis rs9303401 1.000 rs9904677 chr17:56873025 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.42 6.37 0.33 6.08e-10 Cognitive test performance; LIHC cis rs362296 0.698 rs3095081 chr4:3263776 C/T cg06533319 chr4:3265114 C4orf44 0.35 6.52 0.33 2.51e-10 Parental longevity (mother's age at death); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg22874560 chr6:37225361 TMEM217;TBC1D22B -0.53 -6.05 -0.31 3.78e-9 Lung function (FEV1); LIHC cis rs10461617 0.617 rs1423623 chr5:56065575 A/G cg24531977 chr5:56204891 C5orf35 0.57 8.73 0.43 1.11e-16 Type 2 diabetes; LIHC cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg06634786 chr22:41940651 POLR3H -0.81 -8.68 -0.42 1.62e-16 Vitiligo; LIHC cis rs7520050 0.966 rs11211241 chr1:46452683 T/A cg03146154 chr1:46216737 IPP -0.38 -6.26 -0.32 1.17e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4423214 1.000 rs12791871 chr11:71164544 A/C cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC cis rs17125944 0.615 rs2357945 chr14:53318434 A/G cg00686598 chr14:53173677 PSMC6 -0.78 -9.33 -0.45 1.36e-18 Alzheimer's disease (late onset); LIHC cis rs7647973 0.626 rs1586827 chr3:49671224 T/C cg03060546 chr3:49711283 APEH 0.61 7.02 0.35 1.19e-11 Menarche (age at onset); LIHC cis rs12079745 0.590 rs12095526 chr1:169401827 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.73 -6.71 -0.34 8.31e-11 QT interval; LIHC cis rs668210 0.947 rs559161 chr11:65761637 A/G cg02202077 chr11:65769826 EIF1AD;BANF1 0.55 6.8 0.35 4.71e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs35883536 0.967 rs2297713 chr1:101092766 T/G cg14515779 chr1:101123966 NA -0.67 -13.11 -0.58 4.4e-32 Monocyte count; LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg06558623 chr16:89946397 TCF25 0.99 14.86 0.63 7.07e-39 Skin colour saturation; LIHC cis rs6061231 0.793 rs2427320 chr20:60976723 A/G cg06026331 chr20:60912101 LAMA5 0.48 6.44 0.33 4.05e-10 Colorectal cancer; LIHC cis rs4819052 0.851 rs7275874 chr21:46671223 C/T cg22633049 chr21:46681294 NA -0.37 -6.34 -0.32 7.23e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4243830 0.737 rs11581831 chr1:6609958 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.85 -10.84 -0.51 1.02e-23 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03185820 chr7:149158252 ZNF777 0.47 7.36 0.37 1.38e-12 Cognitive function; LIHC cis rs9916302 0.660 rs4795367 chr17:37608843 G/C cg07936489 chr17:37558343 FBXL20 -0.86 -12.36 -0.56 2.95e-29 Glomerular filtration rate (creatinine); LIHC trans rs2270927 0.510 rs35764719 chr5:75573550 G/T cg13563193 chr19:33072644 PDCD5 0.95 9.22 0.45 3.07e-18 Mean corpuscular volume; LIHC cis rs6754311 0.731 rs309164 chr2:136691825 T/C cg07305463 chr2:136567211 LCT -0.37 -7.17 -0.36 4.76e-12 Mosquito bite size; LIHC cis rs4423214 0.592 rs10898223 chr11:71219264 G/A cg05163923 chr11:71159392 DHCR7 -0.57 -6.95 -0.35 1.87e-11 Vitamin D levels; LIHC cis rs12477438 0.520 rs11883676 chr2:99800814 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.66 0.65 4.89e-42 Chronic sinus infection; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg01012308 chr16:3767753 TRAP1 -0.39 -6.18 -0.32 1.79e-9 Eotaxin levels; LIHC cis rs1198430 0.683 rs1198440 chr1:23780861 C/A cg13183780 chr1:23809682 ASAP3 -0.37 -6.46 -0.33 3.6e-10 Total cholesterol levels; LIHC cis rs1577917 1.000 rs1962716 chr6:86648436 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.49 -0.33 3.02e-10 Response to antipsychotic treatment; LIHC cis rs208520 0.874 rs208456 chr6:66907942 A/G cg07460842 chr6:66804631 NA -0.7 -7.62 -0.38 2.52e-13 Exhaled nitric oxide output; LIHC cis rs17152411 1.000 rs2241541 chr10:126671673 T/C cg07906193 chr10:126599966 NA 0.5 7.84 0.39 5.77e-14 Height; LIHC cis rs6429082 0.755 rs291384 chr1:235644300 C/T cg26050004 chr1:235667680 B3GALNT2 0.49 7.48 0.38 6.27e-13 Adiposity; LIHC cis rs1461503 0.966 rs10790545 chr11:122838350 G/C cg14473756 chr11:122847823 NA -0.37 -6.67 -0.34 1.02e-10 Menarche (age at onset); LIHC cis rs922107 0.738 rs12118443 chr1:90038588 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.6 -0.38 2.8e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7020830 0.898 rs997318 chr9:37364094 C/T cg14294708 chr9:37120828 ZCCHC7 1.03 21.19 0.75 2.92e-64 Schizophrenia; LIHC cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg07414643 chr4:187882934 NA 0.23 5.97 0.31 6.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1882538 0.551 rs6974618 chr7:133084031 C/A cg10665199 chr7:133106180 EXOC4 0.5 8.24 0.41 3.6e-15 Intelligence (multi-trait analysis); LIHC trans rs75804782 0.641 rs56396448 chr2:239335234 C/T cg01134436 chr17:81009848 B3GNTL1 0.83 6.91 0.35 2.44e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs2404602 0.684 rs1011084 chr15:77007480 C/G cg03037974 chr15:76606532 NA -0.58 -9.79 -0.47 4.01e-20 Blood metabolite levels; LIHC cis rs9733 0.596 rs12089731 chr1:150647798 T/C cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC trans rs743793 0.875 rs137386 chr22:33580920 C/T cg20274824 chr1:36638199 MAP7D1 0.46 6.42 0.33 4.66e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs5769707 0.521 rs9616715 chr22:50058582 C/T cg01652190 chr22:50026171 C22orf34 -0.29 -6.34 -0.32 7.24e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6089829 0.925 rs6062396 chr20:61667949 T/C cg08564027 chr20:61660810 NA 0.4 7.59 0.38 3.02e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs3749237 0.595 rs4855861 chr3:49525962 G/T cg03060546 chr3:49711283 APEH 0.63 10.23 0.48 1.35e-21 Resting heart rate; LIHC cis rs611744 0.647 rs689275 chr8:109241822 T/C cg21045802 chr8:109455806 TTC35 0.58 10.22 0.48 1.42e-21 Dupuytren's disease; LIHC cis rs9393777 0.623 rs3757150 chr6:26476782 T/A cg12826209 chr6:26865740 GUSBL1 0.66 6.97 0.35 1.65e-11 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01459673 chr8:95907442 CCNE2 -0.42 -6.33 -0.32 7.51e-10 Longevity; LIHC cis rs10861342 0.786 rs11112393 chr12:105548053 C/T cg23923672 chr12:105501055 KIAA1033 0.69 8.54 0.42 4.33e-16 IgG glycosylation; LIHC cis rs507080 0.885 rs4938530 chr11:118560570 G/T cg04173919 chr11:118528438 PHLDB1 0.35 6.61 0.34 1.44e-10 Serum metabolite levels; LIHC cis rs4919087 0.926 rs7072078 chr10:99026509 G/A cg25902810 chr10:99078978 FRAT1 0.66 9.65 0.46 1.17e-19 Monocyte count; LIHC cis rs9473924 0.542 rs67538952 chr6:50894400 T/C cg14470998 chr6:50812995 TFAP2B 0.94 10.94 0.51 4.27e-24 Body mass index; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg02447287 chr2:238707023 RBM44 0.41 6.31 0.32 8.46e-10 Bilirubin levels; LIHC cis rs4586057 0.514 rs7083729 chr10:92624670 T/C cg14313238 chr10:92632228 RPP30 0.37 6.15 0.32 2.2e-9 Economic and political preferences (time); LIHC trans rs1974653 0.781 rs175162 chr22:20113253 A/C cg20152630 chr19:46405944 MYPOP 0.47 6.07 0.31 3.48e-9 Schizophrenia; LIHC cis rs1865760 0.892 rs2328903 chr6:25935765 T/C cg03264133 chr6:25882463 NA -0.41 -6.22 -0.32 1.48e-9 Height; LIHC cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg13047869 chr3:10149882 C3orf24 0.55 6.53 0.33 2.39e-10 Alzheimer's disease; LIHC cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg19774624 chr17:42201019 HDAC5 -0.78 -12.11 -0.55 2.45e-28 Total body bone mineral density; LIHC cis rs10256972 0.967 rs1881122 chr7:1040946 A/T cg07308232 chr7:1071921 C7orf50 -0.49 -8.15 -0.4 7.18e-15 Longevity;Endometriosis; LIHC cis rs4665809 1.000 rs11126340 chr2:26253255 A/G cg04944784 chr2:26401820 FAM59B -0.68 -8.45 -0.42 8.7e-16 Gut microbiome composition (summer); LIHC trans rs9956878 0.555 rs8085188 chr18:73544676 A/G cg26618056 chr16:25043323 NA -0.42 -6.1 -0.31 2.86e-9 Obesity-related traits; LIHC cis rs738321 0.757 rs12329956 chr22:38535946 G/A cg25457927 chr22:38595422 NA -0.3 -6.84 -0.35 3.62e-11 Breast cancer; LIHC cis rs7412746 0.621 rs11204749 chr1:150929563 G/A cg18016565 chr1:150552671 MCL1 0.49 9.32 0.45 1.49e-18 Melanoma; LIHC cis rs6088590 0.965 rs6087619 chr20:33288511 C/G cg08999081 chr20:33150536 PIGU 0.4 6.15 0.32 2.12e-9 Coronary artery disease; LIHC cis rs9910055 0.571 rs10208 chr17:42300278 C/T cg13607699 chr17:42295918 UBTF 0.79 16.64 0.67 5.93e-46 Total body bone mineral density; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg00280220 chr17:61926910 NA 0.42 6.87 0.35 3.08e-11 Prudent dietary pattern; LIHC cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg07636037 chr3:49044803 WDR6 0.76 12.66 0.56 2.2e-30 Menarche (age at onset); LIHC cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg12310025 chr6:25882481 NA 0.51 6.39 0.33 5.45e-10 Intelligence (multi-trait analysis); LIHC cis rs8141529 0.509 rs5762863 chr22:29253335 A/C cg02153584 chr22:29168773 CCDC117 0.55 8.12 0.4 8.48e-15 Lymphocyte counts; LIHC cis rs2153535 0.580 rs2152347 chr6:8474281 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs896854 0.517 rs9643353 chr8:95957063 A/G cg16049864 chr8:95962084 TP53INP1 0.47 7.57 0.38 3.62e-13 Type 2 diabetes; LIHC cis rs7129220 0.623 rs35815123 chr11:10119764 G/A cg01453529 chr11:10209919 SBF2 -0.39 -6.93 -0.35 2.13e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs7131987 1.000 rs7131987 chr12:29406488 G/T cg00204748 chr12:29376779 FAR2 0.44 8.27 0.41 2.93e-15 QT interval; LIHC cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg08048268 chr3:133502702 NA -0.42 -6.2 -0.32 1.67e-9 Iron status biomarkers; LIHC cis rs7412746 0.611 rs11204747 chr1:150927152 A/G cg18016565 chr1:150552671 MCL1 -0.48 -9.29 -0.45 1.78e-18 Melanoma; LIHC cis rs67478160 0.679 rs8011109 chr14:104279974 G/A cg08213375 chr14:104286397 PPP1R13B 0.65 12.64 0.56 2.5e-30 Schizophrenia; LIHC trans rs801193 0.967 rs2707853 chr7:66214010 G/A cg26939375 chr7:64535504 NA 0.42 6.71 0.34 8.22e-11 Aortic root size; LIHC cis rs4819052 0.851 rs9977178 chr21:46664531 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 11.77 0.54 4.58e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11098499 0.730 rs12505735 chr4:120532956 G/T cg09307838 chr4:120376055 NA 0.72 11.12 0.52 1.01e-24 Corneal astigmatism; LIHC cis rs57590327 0.503 rs4856350 chr3:81503374 G/A cg07356753 chr3:81810745 GBE1 0.46 6.8 0.35 4.6e-11 Extraversion; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg18110333 chr6:292329 DUSP22 -0.54 -7.15 -0.36 5.27e-12 Menopause (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27493151 chr19:38701994 DPF1 0.39 6.04 0.31 4.13e-9 Longevity; LIHC cis rs12079745 0.793 rs10919104 chr1:169209118 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.78 -6.9 -0.35 2.59e-11 QT interval; LIHC trans rs867371 1.000 rs6495642 chr15:82457497 G/C cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.37 -0.33 6.01e-10 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.23e-9 Menopause (age at onset); LIHC cis rs2153535 0.541 rs9405386 chr6:8458067 C/G cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs7582180 0.700 rs11685401 chr2:100976685 A/G cg14675211 chr2:100938903 LONRF2 0.52 7.81 0.39 6.99e-14 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.623 rs383436 chr17:28959179 A/G cg13385521 chr17:29058706 SUZ12P 0.65 6.12 0.31 2.58e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg25072359 chr17:41440525 NA 0.38 6.2 0.32 1.67e-9 Menopause (age at onset); LIHC cis rs7172677 0.768 rs12148425 chr15:75354972 T/C cg17294928 chr15:75287854 SCAMP5 0.44 6.15 0.32 2.16e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7224314 1.000 rs62084076 chr17:65383102 G/A cg01507342 chr17:65387096 PITPNC1 -0.48 -6.06 -0.31 3.67e-9 Diisocyanate-induced asthma; LIHC cis rs7937682 0.924 rs875257 chr11:111530453 A/G cg09085632 chr11:111637200 PPP2R1B -1.04 -13.22 -0.58 1.56e-32 Primary sclerosing cholangitis; LIHC cis rs2404602 0.669 rs17367297 chr15:77158026 A/C cg23625390 chr15:77176239 SCAPER 0.35 5.74 0.3 2.04e-8 Blood metabolite levels; LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg24209194 chr3:40518798 ZNF619 0.56 8.11 0.4 9.02e-15 Renal cell carcinoma; LIHC trans rs1814175 0.817 rs11040651 chr11:49938395 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg10217327 chr6:118973057 C6orf204 0.69 7.04 0.36 1.03e-11 Diastolic blood pressure; LIHC cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg11502198 chr6:26597334 ABT1 0.61 9.76 0.47 5.35e-20 Intelligence (multi-trait analysis); LIHC cis rs2073499 0.935 rs3755832 chr3:50305234 G/A cg12708802 chr3:50388878 TUSC4;CYB561D2 0.64 6.7 0.34 8.47e-11 Schizophrenia; LIHC cis rs7412746 0.634 rs12409208 chr1:150860055 A/G cg17724175 chr1:150552817 MCL1 0.43 8.34 0.41 1.82e-15 Melanoma; LIHC cis rs807669 0.903 rs2800974 chr22:19168087 C/T cg02655711 chr22:19163373 SLC25A1 0.73 11.24 0.52 3.58e-25 Metabolite levels; LIHC cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg11764359 chr7:65958608 NA -0.66 -8.93 -0.43 2.69e-17 Aortic root size; LIHC cis rs67478160 0.643 rs12434686 chr14:104316033 C/T cg08213375 chr14:104286397 PPP1R13B -0.65 -12.41 -0.56 1.82e-29 Schizophrenia; LIHC trans rs2727020 0.754 rs1851990 chr11:49413336 C/T cg03929089 chr4:120376271 NA -0.7 -11.01 -0.51 2.49e-24 Coronary artery disease; LIHC cis rs507080 0.845 rs509641 chr11:118558952 T/C cg04173919 chr11:118528438 PHLDB1 0.35 6.56 0.33 2.01e-10 Serum metabolite levels; LIHC cis rs4237845 0.761 rs11172378 chr12:58298161 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.45 6.26 0.32 1.16e-9 Intelligence (multi-trait analysis); LIHC cis rs61863818 0.709 rs10786343 chr10:99159465 C/A cg06359132 chr10:99160096 RRP12 -0.41 -6.45 -0.33 3.79e-10 Monocyte percentage of white cells; LIHC cis rs1691799 0.799 rs10784525 chr12:66772766 G/A cg16791601 chr12:66731901 HELB -0.54 -12.56 -0.56 5.03e-30 White blood cell count (basophil); LIHC cis rs9916302 0.904 rs620686 chr17:37453617 A/G cg03013999 chr17:37608204 MED1 -0.36 -6.07 -0.31 3.33e-9 Glomerular filtration rate (creatinine); LIHC cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.06e-11 Alzheimer's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20399842 chr2:21346738 NA 0.41 6.74 0.34 6.88e-11 Longevity; LIHC cis rs9372253 0.934 rs9320327 chr6:110715194 T/A cg01119278 chr6:110721349 DDO -0.31 -6.65 -0.34 1.17e-10 Platelet distribution width; LIHC cis rs9948 1.000 rs72811623 chr2:97496473 C/T cg01990225 chr2:97406019 LMAN2L -0.65 -6.05 -0.31 3.75e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs25645 0.830 rs4072639 chr17:38189049 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.76 14.95 0.63 3.11e-39 Myeloid white cell count; LIHC cis rs2288073 0.801 rs10176347 chr2:24367994 G/A cg06627628 chr2:24431161 ITSN2 -0.52 -6.95 -0.35 1.82e-11 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs11122272 0.735 rs2437148 chr1:231513979 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs2952156 0.920 rs2952152 chr17:37832735 T/C cg00129232 chr17:37814104 STARD3 -0.52 -9.8 -0.47 3.72e-20 Asthma; LIHC cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg03264133 chr6:25882463 NA -0.63 -8.94 -0.44 2.56e-17 Blood metabolite levels; LIHC trans rs1814175 0.817 rs28544182 chr11:50049577 G/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC cis rs2032447 0.530 rs9356996 chr6:26008487 C/A cg18357526 chr6:26021779 HIST1H4A 0.83 11.93 0.54 1.14e-27 Intelligence (multi-trait analysis); LIHC cis rs8072100 0.537 rs9912450 chr17:45402208 C/T cg25173405 chr17:45401733 C17orf57 -0.5 -7.03 -0.36 1.1e-11 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs36051895 0.623 rs7859361 chr9:5237479 C/T cg02405213 chr9:5042618 JAK2 -0.66 -10.64 -0.5 5.12e-23 Pediatric autoimmune diseases; LIHC cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg14004847 chr7:1930337 MAD1L1 -0.46 -6.76 -0.34 5.9e-11 Bipolar disorder and schizophrenia; LIHC cis rs950169 0.580 rs11636189 chr15:85193554 G/A cg17507749 chr15:85114479 UBE2QP1 0.68 7.92 0.39 3.27e-14 Schizophrenia; LIHC cis rs9325144 0.560 rs10785562 chr12:38637419 A/C cg26384229 chr12:38710491 ALG10B -0.57 -8.06 -0.4 1.33e-14 Morning vs. evening chronotype; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg01516881 chr6:292596 DUSP22 0.51 6.61 0.34 1.51e-10 Menopause (age at onset); LIHC cis rs6752107 0.967 rs12162308 chr2:234172188 C/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.56 8.54 0.42 4.57e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7582720 1.000 rs72934763 chr2:203758396 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs6598955 0.671 rs7544 chr1:26607726 T/G cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs2749592 0.588 rs2504144 chr10:38383525 C/T cg25427524 chr10:38739819 LOC399744 -0.64 -11.45 -0.53 6.29e-26 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2153535 0.580 rs2327053 chr6:8443127 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.26 0.41 3.14e-15 Motion sickness; LIHC cis rs734999 0.566 rs6664969 chr1:2534978 G/A cg18854424 chr1:2615690 NA 0.32 7.06 0.36 9.6e-12 Ulcerative colitis; LIHC trans rs916888 0.821 rs199505 chr17:44859410 A/G cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg24642844 chr7:1081250 C7orf50 -0.65 -6.71 -0.34 8.29e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7903847 0.642 rs10882913 chr10:99141845 C/T cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs8078723 0.690 rs3785549 chr17:38149724 T/C cg17467752 chr17:38218738 THRA -0.59 -10.14 -0.48 2.72e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs11252926 0.583 rs2066317 chr10:520309 C/T cg09445902 chr10:555545 DIP2C -0.4 -6.46 -0.33 3.7e-10 Psychosis in Alzheimer's disease; LIHC cis rs11690935 0.550 rs7584187 chr2:172866105 A/G cg13550731 chr2:172543902 DYNC1I2 -0.44 -6.74 -0.34 6.9e-11 Schizophrenia; LIHC cis rs7223966 1.000 rs11657081 chr17:61792339 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 7.11 0.36 6.66e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs876084 0.505 rs62526984 chr8:121128068 A/G cg06265175 chr8:121136014 COL14A1 0.49 7.84 0.39 5.83e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7684253 0.587 rs4339274 chr4:57747634 A/G cg26694713 chr4:57773883 REST 0.43 6.13 0.31 2.37e-9 Migraine; LIHC trans rs2727020 0.930 rs1164688 chr11:49290604 C/G cg18944383 chr4:111397179 ENPEP -0.28 -6.46 -0.33 3.62e-10 Coronary artery disease; LIHC cis rs2842992 0.789 rs2146163 chr6:160224346 T/C cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.9 0.43 3.4e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs7103648 0.897 rs35032070 chr11:47408592 G/A cg20307385 chr11:47447363 PSMC3 0.86 12.49 0.56 9.45e-30 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs932287 0.540 rs4910442 chr11:9044337 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.37 6.11 0.31 2.72e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg24580635 chr7:76178542 LOC100133091 -0.45 -6.52 -0.33 2.47e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2153535 0.541 rs6938688 chr6:8521629 G/T cg21535247 chr6:8435926 SLC35B3 0.63 8.31 0.41 2.3e-15 Motion sickness; LIHC cis rs10927875 1.000 rs3979179 chr1:16306846 A/G cg07117364 chr1:16154769 NA 0.37 5.72 0.3 2.29e-8 Dilated cardiomyopathy; LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.72 -11.99 -0.54 6.97e-28 Height; LIHC cis rs4845459 0.967 rs6677595 chr1:152590187 C/T cg20634798 chr1:152595351 LCE3A -0.31 -6.13 -0.31 2.46e-9 Psoriasis; LIHC cis rs8180040 0.676 rs7636252 chr3:47013542 T/G cg02527881 chr3:46936655 PTH1R -0.36 -7.3 -0.37 2e-12 Colorectal cancer; LIHC trans rs877282 0.898 rs11253350 chr10:765968 G/A cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs7116495 0.609 rs2852365 chr11:71715218 T/C cg10381502 chr11:71823885 C11orf51 -1.06 -9.3 -0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs1538970 1.000 rs2492840 chr1:45849792 C/A cg24296786 chr1:45957014 TESK2 -0.5 -7.57 -0.38 3.54e-13 Platelet count; LIHC cis rs9905704 0.647 rs12944274 chr17:57041293 C/G cg05425664 chr17:57184151 TRIM37 0.43 5.96 0.31 6.44e-9 Testicular germ cell tumor; LIHC cis rs8177253 1.000 rs8177272 chr3:133482870 C/T cg12373951 chr3:133503437 NA 0.69 12.23 0.55 9.12e-29 Iron status biomarkers; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg17875760 chr17:1802361 RPA1 0.48 7.04 0.36 1.06e-11 Hepatitis; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15611993 chr17:14110542 COX10 0.41 6.12 0.31 2.5e-9 Calcium levels; LIHC cis rs7662987 0.517 rs1311617 chr4:100012425 T/G cg12011299 chr4:100065546 ADH4 0.65 10.73 0.5 2.43e-23 Smoking initiation; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg10217327 chr6:118973057 C6orf204 0.69 7.04 0.36 1.03e-11 Diastolic blood pressure; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg06873352 chr17:61820015 STRADA 0.72 12.51 0.56 8.03e-30 Prudent dietary pattern; LIHC cis rs11676348 0.846 rs4674260 chr2:219002376 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.13 -0.31 2.46e-9 Ulcerative colitis; LIHC cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg13393036 chr8:95962371 TP53INP1 -0.39 -8.84 -0.43 5.27e-17 Type 2 diabetes; LIHC cis rs9818758 0.607 rs66991555 chr3:49228643 A/G cg07636037 chr3:49044803 WDR6 -0.8 -8.16 -0.4 6.27e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs826838 1.000 rs10880785 chr12:38655405 T/G cg26384229 chr12:38710491 ALG10B 1.08 14.69 0.62 3.18e-38 Heart rate; LIHC cis rs477895 0.713 rs12575642 chr11:63979643 G/T cg05555928 chr11:63887634 MACROD1 0.44 5.74 0.3 2.09e-8 Mean platelet volume; LIHC cis rs12188164 0.543 rs2434694 chr5:462734 C/T cg24955955 chr5:415729 AHRR 0.32 6.63 0.34 1.28e-10 Cystic fibrosis severity; LIHC cis rs1552244 0.816 rs56387520 chr3:10042782 C/T cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs7772486 0.641 rs9390374 chr6:146368175 A/T cg13319975 chr6:146136371 FBXO30 -0.54 -8.4 -0.41 1.24e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.817 rs12198065 chr6:146385286 G/C cg23711669 chr6:146136114 FBXO30 0.66 11.63 0.53 1.47e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs6061231 1.000 rs11696991 chr20:60959694 G/T cg03945807 chr20:60948434 NA 0.39 6.39 0.33 5.51e-10 Colorectal cancer; LIHC cis rs9470366 0.816 rs1321310 chr6:36623124 C/T cg08179530 chr6:36648295 CDKN1A -0.55 -6.76 -0.34 6.03e-11 QRS duration; LIHC cis rs1005277 0.505 rs200939 chr10:38139483 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.61 -0.56 3.48e-30 Extrinsic epigenetic age acceleration; LIHC cis rs34779708 0.966 rs878264 chr10:35440581 T/C cg04310649 chr10:35416472 CREM -0.42 -5.78 -0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11168351 0.927 rs7971880 chr12:48391055 C/T cg21466736 chr12:48725269 NA -0.56 -7.58 -0.38 3.22e-13 Bipolar disorder and schizophrenia; LIHC cis rs1005277 0.579 rs2749612 chr10:38488610 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.28 -0.32 1.02e-9 Extrinsic epigenetic age acceleration; LIHC trans rs11098499 0.954 rs7436506 chr4:120393769 T/C cg25214090 chr10:38739885 LOC399744 0.58 9.67 0.46 1.07e-19 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs807669 0.903 rs2854643 chr22:19189706 T/C cg02655711 chr22:19163373 SLC25A1 0.72 11.02 0.51 2.35e-24 Metabolite levels; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg00802000 chr16:706648 WDR90 -0.34 -5.71 -0.3 2.39e-8 Height; LIHC cis rs2412459 1.000 rs8023482 chr15:40307095 A/C cg16127683 chr15:40268777 EIF2AK4 -0.63 -8.06 -0.4 1.33e-14 Response to haloperidol in psychosis; LIHC cis rs9303401 0.646 rs7213269 chr17:57237796 C/T cg12560992 chr17:57184187 TRIM37 0.52 7.16 0.36 4.9e-12 Cognitive test performance; LIHC cis rs10791097 0.720 rs6590516 chr11:130733393 G/T cg22079354 chr11:130786696 SNX19 0.42 6.09 0.31 2.98e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs72653721 0.938 rs72653722 chr6:10976212 A/C cg13562911 chr6:11044106 ELOVL2 0.52 7.22 0.36 3.43e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs7412746 0.611 rs9661876 chr1:150910911 C/T cg18016565 chr1:150552671 MCL1 0.5 9.51 0.46 3.62e-19 Melanoma; LIHC cis rs7715806 0.500 rs2307115 chr5:74990348 T/C cg00601450 chr5:74908170 NA 0.58 7.03 0.36 1.15e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12478296 0.892 rs60042638 chr2:243038707 G/A cg18898632 chr2:242989856 NA -0.58 -7.84 -0.39 5.85e-14 Obesity-related traits; LIHC cis rs34779708 0.966 rs12775548 chr10:35479504 G/T cg03585969 chr10:35415529 CREM 0.85 12.82 0.57 5.41e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs769267 0.895 rs1000237 chr19:19518316 T/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.88 0.3 9.84e-9 Tonsillectomy; LIHC cis rs8027181 0.839 rs8025333 chr15:73025121 A/G cg25632853 chr15:73088954 NA 0.36 6.07 0.31 3.46e-9 Triglyceride levels; LIHC cis rs2274273 1.000 rs7160110 chr14:55594635 A/G cg04306507 chr14:55594613 LGALS3 0.33 6.25 0.32 1.24e-9 Protein biomarker; LIHC cis rs11792861 0.962 rs72607162 chr9:111793719 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.62 0.42 2.56e-16 Menarche (age at onset); LIHC cis rs471756 0.523 rs605001 chr9:223843 T/A cg14500300 chr9:211689 NA 0.27 6.23 0.32 1.36e-9 Mean platelet volume; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15664069 chr6:2989243 DKFZP686I15217 0.54 7.32 0.37 1.82e-12 Lung function (FEV1/FVC); LIHC cis rs6964587 1.000 rs3753108 chr7:91629984 T/G cg17063962 chr7:91808500 NA 1.03 20.74 0.75 1.89e-62 Breast cancer; LIHC cis rs56011263 0.687 rs4690187 chr4:703813 C/T cg17689763 chr4:710664 PCGF3 -0.73 -10.42 -0.49 2.92e-22 White blood cell count; LIHC cis rs2549003 1.000 rs7735073 chr5:131815357 G/A cg02551604 chr5:131831745 NA -0.43 -6.52 -0.33 2.51e-10 Asthma (sex interaction); LIHC cis rs7116495 0.609 rs10736783 chr11:71654143 G/A cg26138937 chr11:71823887 C11orf51 -1.28 -10.0 -0.48 8.22e-21 Severe influenza A (H1N1) infection; LIHC cis rs57244997 0.725 rs7746052 chr6:162436267 G/A cg17173639 chr6:162384350 PARK2 -0.49 -6.42 -0.33 4.48e-10 Mosquito bite size; LIHC cis rs11608355 0.672 rs9943689 chr12:109890339 G/A cg05360138 chr12:110035743 NA 0.68 6.74 0.34 6.66e-11 Neuroticism; LIHC cis rs10088262 0.629 rs7833650 chr8:124822969 C/T cg02993010 chr8:124780839 FAM91A1 -0.46 -5.86 -0.3 1.08e-8 Pancreatic cancer; LIHC trans rs7618501 0.516 rs2856236 chr3:50161717 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.51 -8.1 -0.4 9.86e-15 Intelligence (multi-trait analysis); LIHC cis rs782590 0.935 rs782568 chr2:55881538 T/C cg18811423 chr2:55921094 PNPT1 0.86 13.68 0.59 2.84e-34 Metabolic syndrome; LIHC cis rs1577917 0.958 rs13213551 chr6:86608701 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs1494950 1.000 rs2643079 chr4:14992496 A/G cg12377275 chr4:15005593 CPEB2 -0.79 -6.68 -0.34 9.6e-11 Political ideology; LIHC cis rs8017423 0.967 rs7151776 chr14:90724803 A/G cg14092571 chr14:90743983 NA -0.38 -5.95 -0.31 6.46e-9 Mortality in heart failure; LIHC cis rs116095464 0.558 rs10058428 chr5:235608 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.71 -0.5 2.89e-23 Breast cancer; LIHC cis rs7131987 0.683 rs12366505 chr12:29474110 C/T cg14222432 chr12:29376421 FAR2 0.36 6.93 0.35 2.16e-11 QT interval; LIHC cis rs1552244 0.882 rs66559400 chr3:10012551 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg26939375 chr7:64535504 NA -0.45 -7.94 -0.39 2.89e-14 Calcium levels; LIHC cis rs875971 0.862 rs10950043 chr7:65988610 T/C cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.38e-11 Aortic root size; LIHC cis rs9378688 1.000 rs9405550 chr6:2230064 A/C cg12303981 chr6:2244766 GMDS 0.49 6.18 0.32 1.78e-9 Caudate nucleus volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12600695 chr5:137513806 BRD8;KIF20A 0.47 6.42 0.33 4.52e-10 Pancreatic cancer; LIHC trans rs11671005 0.504 rs3794964 chr19:59070916 T/C cg22037779 chr5:139682734 PFDN1 -0.54 -6.72 -0.34 7.54e-11 Mean platelet volume; LIHC cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3768617 0.510 rs1413389 chr1:183096668 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs2952156 1.000 rs2934971 chr17:37854507 G/T cg00129232 chr17:37814104 STARD3 -0.47 -8.53 -0.42 4.65e-16 Asthma; LIHC cis rs2637266 0.597 rs846615 chr10:78548489 A/G cg18941641 chr10:78392320 NA -0.28 -5.93 -0.31 7.48e-9 Pulmonary function; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06468809 chr16:4378402 NA 0.5 7.12 0.36 6.28e-12 Lung function (FEV1/FVC); LIHC cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg11644478 chr21:40555479 PSMG1 0.81 10.32 0.49 6.41e-22 Cognitive function; LIHC cis rs7617773 0.817 rs4131361 chr3:48328812 T/C cg11946769 chr3:48343235 NME6 0.87 11.29 0.52 2.49e-25 Coronary artery disease; LIHC cis rs7249142 0.549 rs7260127 chr19:19280499 C/T cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B 0.35 5.92 0.3 7.96e-9 IgG glycosylation; LIHC cis rs9303401 0.659 rs35564417 chr17:56718286 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs9649465 0.935 rs3807636 chr7:123368488 G/A cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.15e-15 Migraine; LIHC cis rs1707322 0.835 rs946525 chr1:46487277 A/T cg06784218 chr1:46089804 CCDC17 -0.36 -6.47 -0.33 3.33e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1670533 1.000 rs13107058 chr4:1054379 G/A cg27284194 chr4:1044797 NA 0.6 8.93 0.43 2.6e-17 Recombination rate (females); LIHC cis rs12477438 0.798 rs1349779 chr2:99645055 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.14 -17.23 -0.68 2.46e-48 Chronic sinus infection; LIHC cis rs798554 0.634 rs6978692 chr7:2857411 C/T cg19717773 chr7:2847554 GNA12 -0.42 -7.46 -0.37 7.43e-13 Height; LIHC cis rs9660992 0.710 rs1668867 chr1:205240251 C/T cg21545522 chr1:205238299 TMCC2 0.37 7.23 0.36 3.2e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs8180040 0.966 rs11716763 chr3:47518266 C/T cg27129171 chr3:47204927 SETD2 -0.58 -9.96 -0.47 1.07e-20 Colorectal cancer; LIHC cis rs11971779 0.680 rs6949599 chr7:139054188 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg07092213 chr7:1199455 ZFAND2A -0.48 -7.36 -0.37 1.4e-12 Longevity;Endometriosis; LIHC cis rs10905065 0.895 rs3736462 chr10:5804455 A/G cg11519256 chr10:5708881 ASB13 0.43 5.73 0.3 2.25e-8 Menopause (age at onset); LIHC cis rs8192282 0.739 rs61811362 chr1:154512495 G/A cg16683920 chr1:154474344 TDRD10;SHE 0.53 6.46 0.33 3.6e-10 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); LIHC cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs3936840 0.752 rs2181343 chr14:102993303 A/C cg10241871 chr14:102965420 TECPR2 0.39 6.27 0.32 1.06e-9 Plateletcrit; LIHC cis rs12701220 0.948 rs12690826 chr7:1081618 A/G cg00990874 chr7:1149470 C7orf50 -0.65 -8.95 -0.44 2.37e-17 Bronchopulmonary dysplasia; LIHC cis rs4803455 0.565 rs11083616 chr19:41865643 A/G cg08477640 chr19:41863820 B9D2 -0.33 -5.85 -0.3 1.15e-8 Migraine;Coronary artery disease; LIHC cis rs7428 0.527 rs6547612 chr2:85551184 C/T cg24342717 chr2:85555507 TGOLN2 -0.79 -11.08 -0.51 1.37e-24 Ear protrusion; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19517509 chr12:120933726 DYNLL1 0.42 6.48 0.33 3.16e-10 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03480535 chr4:87856849 AFF1 0.6 9.02 0.44 1.43e-17 Pancreatic cancer; LIHC cis rs240764 0.687 rs1336245 chr6:101197640 A/T cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.34e-9 Neuroticism; LIHC cis rs8180040 0.966 rs3816779 chr3:47543389 C/T cg27129171 chr3:47204927 SETD2 0.56 9.51 0.46 3.4e-19 Colorectal cancer; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg09417038 chr21:47716443 C21orf57 -0.48 -7.23 -0.36 3.1e-12 Testicular germ cell tumor; LIHC cis rs4716602 0.548 rs34245976 chr7:156160897 T/G cg16983916 chr7:156159713 NA -0.32 -5.75 -0.3 2.01e-8 Anti-saccade response; LIHC cis rs61712019 0.679 rs17648803 chr2:77725425 A/T cg11252801 chr2:77748917 LRRTM4 0.55 7.71 0.38 1.36e-13 Schizophrenia; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.6 -11.75 -0.54 5.35e-27 Prudent dietary pattern; LIHC cis rs73001065 0.818 rs58847337 chr19:19726022 G/A cg03709012 chr19:19516395 GATAD2A 0.82 7.64 0.38 2.28e-13 LDL cholesterol; LIHC trans rs916888 0.773 rs199439 chr17:44793503 A/G cg26692224 chr17:62915920 LRRC37A3 -0.72 -6.93 -0.35 2.09e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg18230493 chr5:56204884 C5orf35 0.45 6.01 0.31 4.84e-9 Initial pursuit acceleration; LIHC cis rs523522 0.962 rs4767912 chr12:120981202 A/G cg27279351 chr12:120934652 DYNLL1 0.67 11.98 0.54 7.42e-28 High light scatter reticulocyte count; LIHC cis rs7197653 0.748 rs58542611 chr16:68350219 C/T cg09835421 chr16:68378352 PRMT7 -0.83 -9.47 -0.46 4.92e-19 Magnesium levels; LIHC cis rs10416265 0.528 rs3826906 chr19:33620897 C/T cg27124370 chr19:33622961 WDR88 0.54 7.73 0.39 1.18e-13 Bone properties (heel); LIHC cis rs875971 0.660 rs28698552 chr7:66005018 A/G cg18876405 chr7:65276391 NA 0.44 7.7 0.38 1.44e-13 Aortic root size; LIHC trans rs7613875 0.578 rs4688753 chr3:50074773 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.58 -0.34 1.82e-10 Body mass index; LIHC cis rs17152411 0.901 rs7098050 chr10:126657015 G/T cg07906193 chr10:126599966 NA 0.5 7.73 0.39 1.2e-13 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01525244 chr22:39548611 CBX7 0.5 6.29 0.32 9.84e-10 Lung function (FEV1/FVC); LIHC cis rs6960043 0.875 rs6976381 chr7:15048814 T/C cg19272540 chr7:15055459 NA -0.22 -6.13 -0.31 2.42e-9 Type 2 diabetes; LIHC trans rs116095464 0.558 rs62347677 chr5:227453 A/G cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs13118159 1.000 rs13118159 chr4:1365127 A/G cg13395646 chr4:1353034 KIAA1530 -0.6 -7.93 -0.39 3.05e-14 Longevity; LIHC cis rs6089584 0.927 rs6089593 chr20:60572312 G/A cg13770153 chr20:60521292 NA -0.34 -6.71 -0.34 7.98e-11 Body mass index; LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg19635926 chr16:89946313 TCF25 -0.48 -6.74 -0.34 6.69e-11 Skin colour saturation; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.96 -0.31 6.12e-9 Total body bone mineral density; LIHC cis rs9291683 0.588 rs11732054 chr4:9999877 C/T cg11266682 chr4:10021025 SLC2A9 0.31 6.44 0.33 4.13e-10 Bone mineral density; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.25 0.55 7.25e-29 Prudent dietary pattern; LIHC cis rs138880 0.542 rs9616215 chr22:50318834 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.81 -7.18 -0.36 4.38e-12 Schizophrenia; LIHC cis rs4862750 0.914 rs11945845 chr4:187874136 T/C cg10295955 chr4:187884368 NA -0.96 -21.06 -0.75 1.01e-63 Lobe attachment (rater-scored or self-reported); LIHC trans rs1005277 0.579 rs2505257 chr10:38372664 A/G cg17830980 chr10:43048298 ZNF37B -0.56 -11.35 -0.52 1.45e-25 Extrinsic epigenetic age acceleration; LIHC trans rs1005277 0.522 rs289648 chr10:37971837 T/C cg23533926 chr12:111358616 MYL2 -0.32 -6.34 -0.32 7.37e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9916302 0.904 rs8065879 chr17:37515978 G/A cg07936489 chr17:37558343 FBXL20 0.84 13.6 0.59 5.67e-34 Glomerular filtration rate (creatinine); LIHC cis rs826838 0.967 rs11169387 chr12:39145737 C/T cg13010199 chr12:38710504 ALG10B 0.52 6.28 0.32 1.04e-9 Heart rate; LIHC cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.9 0.3 8.85e-9 Aortic root size; LIHC cis rs2276314 1.000 rs16967317 chr18:33573400 A/G cg05985134 chr18:33552581 C18orf21 0.49 5.79 0.3 1.58e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg18306943 chr3:40428807 ENTPD3 0.42 7.44 0.37 8.23e-13 Renal cell carcinoma; LIHC cis rs427394 1.000 rs427394 chr5:6745875 A/G cg10857441 chr5:6722123 POLS -0.34 -5.82 -0.3 1.36e-8 Menopause (age at onset); LIHC cis rs1494950 1.000 rs17309950 chr4:15073913 G/A cg12377275 chr4:15005593 CPEB2 -0.87 -7.42 -0.37 9.28e-13 Political ideology; LIHC cis rs2073300 0.609 rs2277765 chr20:23425163 C/T cg12062639 chr20:23401060 NAPB 1.02 13.17 0.58 2.63e-32 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs870825 0.616 rs1401359 chr4:185640216 T/C cg04058563 chr4:185651563 MLF1IP 0.76 7.89 0.39 4.01e-14 Blood protein levels; LIHC cis rs8141529 0.764 rs5762854 chr22:29246278 T/C cg02153584 chr22:29168773 CCDC117 0.57 9.14 0.44 5.57e-18 Lymphocyte counts; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg17096262 chr10:29759227 SVIL 0.36 6.18 0.32 1.86e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.04 0.44 1.19e-17 Bipolar disorder; LIHC cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg00149659 chr3:10157352 C3orf10 0.7 7.1 0.36 7.09e-12 Alzheimer's disease; LIHC cis rs7927592 0.913 rs7925275 chr11:68290433 T/C cg01657329 chr11:68192670 LRP5 -0.47 -6.0 -0.31 4.96e-9 Total body bone mineral density; LIHC cis rs9733 0.569 rs11588404 chr1:150688529 C/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg08219700 chr8:58056026 NA 0.52 6.22 0.32 1.43e-9 Developmental language disorder (linguistic errors); LIHC cis rs9303401 1.000 rs9303401 chr17:56847945 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.42 6.37 0.33 6.08e-10 Cognitive test performance; LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg06873352 chr17:61820015 STRADA 0.73 13.12 0.58 3.97e-32 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15312298 chr8:127570908 FAM84B 0.46 7.24 0.36 2.95e-12 Pancreatic cancer; LIHC cis rs72627123 0.867 rs77320708 chr14:74478482 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.75 0.47 5.75e-20 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs6545883 0.894 rs778144 chr2:61583128 A/C cg15711740 chr2:61764176 XPO1 0.43 5.87 0.3 1.01e-8 Tuberculosis; LIHC cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg08392591 chr16:89556376 ANKRD11 0.54 8.66 0.42 1.93e-16 Multiple myeloma (IgH translocation); LIHC cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.89 0.57 2.95e-31 Alzheimer's disease; LIHC cis rs35110281 0.501 rs162378 chr21:44925905 A/G cg21573476 chr21:45109991 RRP1B 0.43 7.65 0.38 2.1e-13 Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00711773 chr3:40351057 EIF1B -0.43 -6.28 -0.32 1.03e-9 Pancreatic cancer; LIHC cis rs2197308 0.765 rs11182434 chr12:37923968 C/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs1707322 0.721 rs28501477 chr1:46199084 A/G cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg02475777 chr4:1388615 CRIPAK 0.42 6.33 0.32 7.8e-10 Longevity; LIHC cis rs1570989 0.841 rs9369032 chr6:12025822 C/T cg17804551 chr6:12015979 HIVEP1 -0.4 -5.96 -0.31 6.27e-9 Alcohol and nicotine co-dependence; LIHC cis rs8180040 0.764 rs62246375 chr3:47014464 G/A cg16586182 chr3:47516702 SCAP 0.49 8.95 0.44 2.39e-17 Colorectal cancer; LIHC cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg04083430 chr16:4736063 MGRN1 -0.43 -5.81 -0.3 1.44e-8 Schizophrenia; LIHC cis rs17685 0.753 rs8200 chr7:75696606 C/G cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.1 0.31 2.92e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8180040 0.701 rs11917474 chr3:47010491 G/A cg02527881 chr3:46936655 PTH1R -0.35 -7.16 -0.36 5.02e-12 Colorectal cancer; LIHC cis rs9309711 0.623 rs7569694 chr2:3483390 T/G cg04359351 chr2:3481828 TTC15 0.28 5.94 0.31 7.04e-9 Neurofibrillary tangles; LIHC cis rs9368481 0.569 rs10946868 chr6:26887930 A/G cg18867708 chr6:26865862 GUSBL1 0.55 8.31 0.41 2.23e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs9457247 0.579 rs2181059 chr6:167441624 T/C cg12798992 chr6:167411361 FGFR1OP 0.53 8.71 0.43 1.29e-16 Crohn's disease; LIHC cis rs754466 1.000 rs754466 chr10:79680434 A/T cg17075019 chr10:79541650 NA -0.62 -8.39 -0.41 1.31e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17152411 0.843 rs7896051 chr10:126583119 T/C cg07906193 chr10:126599966 NA 0.43 6.84 0.35 3.73e-11 Height; LIHC cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg20090690 chr10:134436459 INPP5A 0.44 5.71 0.3 2.44e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs372883 0.600 rs2832293 chr21:30738872 C/G cg24692254 chr21:30365293 RNF160 0.49 6.21 0.32 1.57e-9 Pancreatic cancer; LIHC trans rs2727020 0.688 rs11040338 chr11:49360601 A/G cg15704280 chr7:45808275 SEPT13 0.92 17.23 0.68 2.4e-48 Coronary artery disease; LIHC cis rs1198430 0.602 rs12401753 chr1:23762679 A/G cg13183780 chr1:23809682 ASAP3 -0.35 -6.28 -0.32 1.05e-9 Total cholesterol levels; LIHC cis rs2204008 0.837 rs11168341 chr12:37961951 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs769267 0.895 rs2916069 chr19:19520358 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.04 0.4 1.49e-14 Tonsillectomy; LIHC cis rs2072499 0.833 rs2251636 chr1:156202809 G/C cg24450063 chr1:156163899 SLC25A44 0.72 12.43 0.56 1.57e-29 Testicular germ cell tumor; LIHC cis rs1538970 0.962 rs2487442 chr1:45857176 C/G cg05343316 chr1:45956843 TESK2 -0.52 -7.84 -0.39 5.84e-14 Platelet count; LIHC cis rs477692 0.905 rs570967 chr10:131421330 T/G cg19680672 chr10:131412579 MGMT -0.42 -6.58 -0.34 1.75e-10 Response to temozolomide; LIHC cis rs4919087 0.962 rs10882891 chr10:99059645 C/A cg25902810 chr10:99078978 FRAT1 0.71 10.92 0.51 5.26e-24 Monocyte count; LIHC cis rs7772486 0.790 rs2247429 chr6:146217769 T/C cg13319975 chr6:146136371 FBXO30 -0.39 -6.19 -0.32 1.72e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs16922576 0.656 rs2093448 chr9:5230444 T/G cg02405213 chr9:5042618 JAK2 -0.64 -9.87 -0.47 2.26e-20 Allergic disease (asthma, hay fever or eczema); LIHC cis rs12702595 0.553 rs6463661 chr7:7259370 G/A cg04827551 chr7:7268805 C1GALT1 0.33 6.15 0.32 2.16e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs4713118 0.662 rs156744 chr6:27967274 G/A cg16479474 chr6:28041457 NA 0.45 6.78 0.34 5.41e-11 Parkinson's disease; LIHC cis rs12995491 0.933 rs34029976 chr2:88537797 T/C cg04511125 chr2:88470314 THNSL2 -0.43 -6.49 -0.33 2.98e-10 Response to metformin (IC50); LIHC trans rs12204683 0.963 rs2629470 chr6:80176289 A/G cg03122264 chr6:127797208 C6orf174 -0.48 -6.29 -0.32 9.65e-10 Presence of antiphospholipid antibodies; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg08853494 chr4:76439657 RCHY1;THAP6 -0.43 -6.2 -0.32 1.64e-9 Alopecia areata; LIHC cis rs12644436 0.628 rs4693890 chr4:88783734 G/C cg06891869 chr4:88767617 MEPE 0.43 7.62 0.38 2.59e-13 HIV-1 viral setpoint; LIHC cis rs8180040 0.701 rs1079276 chr3:47045739 C/G cg16586182 chr3:47516702 SCAP -0.48 -8.86 -0.43 4.6e-17 Colorectal cancer; LIHC cis rs243505 0.762 rs10241408 chr7:148481488 G/A cg09806900 chr7:148480153 CUL1 0.45 6.7 0.34 8.62e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7546668 1.000 rs2295626 chr1:15874961 T/A cg11706911 chr1:15910989 AGMAT 0.44 6.71 0.34 8.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs4653663 0.533 rs4653660 chr1:225915468 G/C cg20799095 chr1:225924665 NA 0.37 5.71 0.3 2.43e-8 Neuroticism; LIHC cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg17971929 chr21:40555470 PSMG1 0.84 10.05 0.48 5.24e-21 Cognitive function; LIHC cis rs12908161 0.960 rs11633450 chr15:85307287 C/T cg12863693 chr15:85201151 NMB 0.44 6.16 0.32 2.06e-9 Schizophrenia; LIHC cis rs10751667 0.580 rs10751664 chr11:927077 T/G ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC cis rs4820294 0.516 rs12484441 chr22:38097359 C/G cg00142150 chr22:38071001 LGALS1 0.63 8.24 0.41 3.69e-15 Fat distribution (HIV); LIHC cis rs1401999 1.000 rs6800217 chr3:183685893 T/C cg01324343 chr3:183735012 ABCC5 0.78 12.88 0.57 3.2e-31 Anterior chamber depth; LIHC cis rs7833790 1.000 rs7833790 chr8:82731157 T/C cg17211192 chr8:82754475 SNX16 -0.67 -11.99 -0.54 6.78e-28 Diastolic blood pressure; LIHC cis rs798554 0.797 rs798491 chr7:2800521 A/G cg13628971 chr7:2884303 GNA12 0.53 7.81 0.39 7.09e-14 Height; LIHC trans rs4942242 0.663 rs9525815 chr13:44223692 T/C cg19169023 chr15:41853346 TYRO3 -0.54 -7.49 -0.38 5.92e-13 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs1005277 0.579 rs1740735 chr10:38497777 A/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.05 -0.44 1.13e-17 Extrinsic epigenetic age acceleration; LIHC cis rs2404602 0.716 rs12907805 chr15:76690606 C/T cg23625390 chr15:77176239 SCAPER 0.37 6.13 0.31 2.44e-9 Blood metabolite levels; LIHC cis rs5769765 0.908 rs9627800 chr22:50319351 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.41 -0.45 7.59e-19 Schizophrenia; LIHC cis rs1577917 0.958 rs1591438 chr6:86525214 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.47 -0.37 6.81e-13 Response to antipsychotic treatment; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg08867150 chr8:28259493 NA -0.6 -6.06 -0.31 3.69e-9 Obesity-related traits; LIHC cis rs2439831 0.541 rs12440854 chr15:43610672 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.8 8.93 0.43 2.74e-17 Lung cancer in ever smokers; LIHC cis rs7937682 0.575 rs34695265 chr11:111719128 T/C cg09085632 chr11:111637200 PPP2R1B 0.96 14.24 0.61 1.84e-36 Primary sclerosing cholangitis; LIHC cis rs6933660 0.760 rs3806982 chr6:151774916 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.63 10.35 0.49 4.98e-22 Menarche (age at onset); LIHC trans rs2727020 0.635 rs7124266 chr11:49280857 T/G cg18944383 chr4:111397179 ENPEP -0.28 -6.47 -0.33 3.38e-10 Coronary artery disease; LIHC cis rs9341808 0.718 rs9352806 chr6:80980057 G/T cg08355045 chr6:80787529 NA 0.35 7.25 0.36 2.87e-12 Sitting height ratio; LIHC cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg23262073 chr20:60523788 NA -0.3 -6.21 -0.32 1.55e-9 Body mass index; LIHC cis rs7107174 1.000 rs4627115 chr11:78007873 T/G cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs12478296 0.792 rs57482298 chr2:243011148 C/A cg06360820 chr2:242988706 NA -0.94 -12.39 -0.56 2.28e-29 Obesity-related traits; LIHC cis rs2073499 1.000 rs79499880 chr3:50259551 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.73 7.51 0.38 5.05e-13 Schizophrenia; LIHC cis rs10771431 0.597 rs10843142 chr12:9357502 A/G cg08997352 chr12:9597637 DDX12 -0.48 -7.48 -0.38 6.17e-13 Breast size; LIHC cis rs6752107 1.000 rs2241878 chr2:234183718 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.47 0.42 7.63e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs7582720 0.943 rs115130739 chr2:203725677 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.76 6.15 0.32 2.15e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs826838 1.000 rs826838 chr12:39106731 C/T cg26384229 chr12:38710491 ALG10B -0.55 -8.45 -0.42 8.19e-16 Heart rate; LIHC trans rs950169 0.614 rs765524 chr15:84681782 G/T cg24036039 chr1:3397125 ARHGEF16 0.37 6.36 0.33 6.6e-10 Schizophrenia; LIHC cis rs4631830 0.900 rs7920517 chr10:51532621 G/A cg20129853 chr10:51489980 NA -0.41 -9.04 -0.44 1.15e-17 Prostate-specific antigen levels; LIHC cis rs240764 0.578 rs11155613 chr6:101176642 T/C cg12253828 chr6:101329408 ASCC3 0.45 7.16 0.36 5.08e-12 Neuroticism; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs6754311 0.731 rs2236783 chr2:136594158 G/A cg07305463 chr2:136567211 LCT 0.38 7.19 0.36 4.04e-12 Mosquito bite size; LIHC cis rs1843834 0.539 rs3912999 chr2:225390089 C/T cg22509189 chr2:225307070 NA -0.82 -11.62 -0.53 1.58e-26 IgE levels in asthmatics (D.p. specific); LIHC cis rs6546550 0.867 rs6738174 chr2:70150215 A/C cg02498382 chr2:70120550 SNRNP27 -0.44 -7.55 -0.38 4.04e-13 Prevalent atrial fibrillation; LIHC cis rs2404602 0.735 rs11857015 chr15:76649390 T/C cg03037974 chr15:76606532 NA -0.63 -11.13 -0.52 9.43e-25 Blood metabolite levels; LIHC cis rs6964587 0.773 rs10488514 chr7:91951842 C/A cg17063962 chr7:91808500 NA 1.0 17.2 0.68 3.31e-48 Breast cancer; LIHC cis rs4862307 0.688 rs6552741 chr4:184990335 A/G cg22054328 chr4:184930219 STOX2 -0.37 -6.42 -0.33 4.68e-10 Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC cis rs1670533 1.000 rs2290408 chr4:1067267 A/C cg27284194 chr4:1044797 NA -0.57 -8.62 -0.42 2.51e-16 Recombination rate (females); LIHC cis rs36051895 0.664 rs884132 chr9:5114522 G/A cg02405213 chr9:5042618 JAK2 -0.64 -10.98 -0.51 3.11e-24 Pediatric autoimmune diseases; LIHC cis rs2180341 0.924 rs9285459 chr6:127631113 T/C cg24812749 chr6:127587940 RNF146 1.07 16.09 0.66 9.4e-44 Breast cancer; LIHC cis rs6775745 0.541 rs16838395 chr3:131755693 A/G cg12213930 chr3:131751605 CPNE4 -0.4 -5.87 -0.3 1.05e-8 Neutrophil count; LIHC cis rs7927771 0.524 rs11039392 chr11:47798753 A/G cg20307385 chr11:47447363 PSMC3 0.72 10.68 0.5 3.75e-23 Subjective well-being; LIHC cis rs909002 0.800 rs3753613 chr1:32082000 C/T cg13919466 chr1:32135498 COL16A1 0.32 6.2 0.32 1.66e-9 Intelligence (multi-trait analysis); LIHC cis rs6466055 0.777 rs66599006 chr7:104934271 A/G cg04380332 chr7:105027541 SRPK2 0.37 6.86 0.35 3.2e-11 Schizophrenia; LIHC cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg05665937 chr4:1216051 CTBP1 0.45 6.08 0.31 3.19e-9 Obesity-related traits; LIHC cis rs644799 0.735 rs10831432 chr11:95516040 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.65 0.56 2.36e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs933688 0.941 rs2887007 chr5:90740531 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 21.15 0.75 4.38e-64 Smoking behavior; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg00656387 chr3:40428638 ENTPD3 -0.5 -8.5 -0.42 5.9e-16 Renal cell carcinoma; LIHC cis rs11792861 0.926 rs7046725 chr9:111882729 T/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.6 8.62 0.42 2.48e-16 Menarche (age at onset); LIHC cis rs9658691 0.607 rs12411452 chr10:90780607 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.93 -6.71 -0.34 8.01e-11 Mosquito bite size; LIHC cis rs2180341 1.000 rs6569477 chr6:127589302 T/A cg27446573 chr6:127587934 RNF146 1.01 15.13 0.63 5.71e-40 Breast cancer; LIHC cis rs7927592 0.830 rs7120635 chr11:68261293 A/G cg01657329 chr11:68192670 LRP5 -0.46 -6.08 -0.31 3.25e-9 Total body bone mineral density; LIHC cis rs10170846 0.861 rs7571732 chr2:223538316 A/C cg25565276 chr2:223520875 FARSB -0.61 -9.01 -0.44 1.48e-17 Schizophrenia (inflammation and infection response interaction); LIHC cis rs2180341 0.782 rs4487601 chr6:127723521 A/G cg27446573 chr6:127587934 RNF146 0.79 13.15 0.58 3.06e-32 Breast cancer; LIHC cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg11890956 chr21:40555474 PSMG1 -0.5 -8.04 -0.4 1.49e-14 Cognitive function; LIHC cis rs3770081 1.000 rs6724025 chr2:86200835 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.84 -10.02 -0.48 7.1e-21 Facial emotion recognition (sad faces); LIHC cis rs507506 0.771 rs929229 chr17:7105399 C/T cg14660024 chr17:7154518 C17orf81;DULLARD -0.33 -6.08 -0.31 3.18e-9 Adiponectin levels; LIHC cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.48 0.56 1.07e-29 Alzheimer's disease; LIHC cis rs6964587 0.626 rs4729014 chr7:91550707 A/G cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.23e-24 Breast cancer; LIHC cis rs875971 0.862 rs10274883 chr7:66116091 C/T cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs9911578 0.835 rs58647683 chr17:56483194 T/C cg12560992 chr17:57184187 TRIM37 -0.91 -15.09 -0.63 8.71e-40 Intelligence (multi-trait analysis); LIHC cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 0.29 6.01 0.31 4.76e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs919433 0.783 rs805497 chr2:198222548 A/T cg10820045 chr2:198174542 NA 0.54 8.98 0.44 1.89e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg09069446 chr16:4462122 CORO7 -0.35 -5.72 -0.3 2.3e-8 Schizophrenia; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg02407032 chr11:47600271 KBTBD4;NDUFS3 -0.45 -6.1 -0.31 2.82e-9 Alopecia areata; LIHC cis rs861318 0.702 rs2852695 chr1:159015933 G/A cg11003133 chr1:159046391 AIM2 0.32 6.27 0.32 1.08e-9 Obesity-related traits; LIHC cis rs9611565 0.649 rs126092 chr22:42178441 A/G cg06634786 chr22:41940651 POLR3H 0.52 5.77 0.3 1.79e-8 Vitiligo; LIHC cis rs7602441 0.521 rs78567942 chr2:14767845 C/A cg06545361 chr2:14773388 FAM84A 0.5 5.89 0.3 9.41e-9 Visceral adipose tissue adjusted for BMI; LIHC cis rs6963495 0.818 rs56251768 chr7:105165591 A/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2832191 0.597 rs8127842 chr21:30516461 G/A cg24692254 chr21:30365293 RNF160 -0.43 -6.76 -0.34 5.87e-11 Dental caries; LIHC cis rs28830936 0.625 rs8038764 chr15:41907905 A/C cg17847044 chr15:42102381 MAPKBP1 0.43 10.11 0.48 3.42e-21 Diastolic blood pressure; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg02726883 chr17:29421732 NF1 -0.43 -6.1 -0.31 2.79e-9 Triglycerides; LIHC cis rs12477438 0.765 rs62156363 chr2:99693324 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.37 -0.41 1.51e-15 Chronic sinus infection; LIHC cis rs7116495 1.000 rs10898814 chr11:71736505 T/C cg26138937 chr11:71823887 C11orf51 -0.81 -8.04 -0.4 1.43e-14 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg20607798 chr8:58055168 NA 0.64 8.27 0.41 3.01e-15 Developmental language disorder (linguistic errors); LIHC cis rs6442522 0.809 rs972685 chr3:15484269 G/A cg16303742 chr3:15540471 COLQ 0.39 6.17 0.32 1.88e-9 Uric acid levels; LIHC cis rs13177918 0.603 rs2748241 chr5:149827494 C/T cg14059543 chr5:149831962 NA -0.48 -7.48 -0.37 6.51e-13 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs227584 0.501 rs62078931 chr17:42198059 A/C cg13607699 chr17:42295918 UBTF -0.36 -5.76 -0.3 1.91e-8 Bone mineral density (hip);Bone mineral density; LIHC cis rs11673344 0.832 rs2011475 chr19:37545614 C/T cg27390819 chr19:37464633 NA -0.5 -6.02 -0.31 4.58e-9 Obesity-related traits; LIHC cis rs9457247 0.765 rs9457256 chr6:167436461 T/C cg07741184 chr6:167504864 NA 0.31 7.2 0.36 3.95e-12 Crohn's disease; LIHC cis rs2029362 0.611 rs2883187 chr11:27741092 G/A cg18117895 chr11:27722066 BDNF -0.41 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs4629710 0.534 rs6916881 chr6:131565153 C/T cg12606694 chr6:131520996 AKAP7 0.59 7.03 0.36 1.16e-11 Multiple myeloma (IgH translocation); LIHC cis rs2637266 0.783 rs7898786 chr10:78481338 T/C cg18941641 chr10:78392320 NA 0.27 5.93 0.31 7.54e-9 Pulmonary function; LIHC cis rs1008375 0.932 rs6841784 chr4:17626418 G/A cg16339924 chr4:17578868 LAP3 0.53 7.05 0.36 1.03e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4474465 0.850 rs6592789 chr11:78246767 G/C cg27205649 chr11:78285834 NARS2 0.42 6.39 0.33 5.55e-10 Alzheimer's disease (survival time); LIHC cis rs12980942 0.872 rs16958994 chr19:41824981 T/C cg25627403 chr19:41769009 HNRNPUL1 0.47 5.91 0.3 8.07e-9 Coronary artery disease; LIHC cis rs238295 0.846 rs6053528 chr20:5582598 G/T cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -6.91 -0.35 2.44e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs9916302 0.653 rs11654954 chr17:37745979 C/T cg00129232 chr17:37814104 STARD3 0.5 7.81 0.39 6.96e-14 Glomerular filtration rate (creatinine); LIHC cis rs2180341 0.842 rs9372860 chr6:127546605 G/A cg24812749 chr6:127587940 RNF146 0.97 12.67 0.57 1.94e-30 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07254608 chr8:41997973 NA 0.43 6.15 0.32 2.12e-9 Pancreatic cancer; LIHC cis rs3796619 0.503 rs1466216 chr4:1071907 C/T cg13468214 chr4:1046988 NA 0.36 6.7 0.34 8.47e-11 Recombination rate (males); LIHC cis rs2075371 0.932 rs34664116 chr7:133984878 G/A cg11752832 chr7:134001865 SLC35B4 0.48 6.06 0.31 3.67e-9 Mean platelet volume; LIHC cis rs992157 0.710 rs12996912 chr2:219110555 A/G cg00012203 chr2:219082015 ARPC2 0.92 16.63 0.67 6.55e-46 Colorectal cancer; LIHC cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg07414643 chr4:187882934 NA 0.24 5.97 0.31 5.99e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs5997397 0.934 rs6005863 chr22:29156448 A/G cg15103426 chr22:29168792 CCDC117 0.56 8.78 0.43 7.88e-17 Red cell distribution width; LIHC cis rs11053548 0.646 rs11053549 chr12:10172178 C/T cg04314261 chr12:10163030 CLEC12B 0.42 6.3 0.32 9.31e-10 Systolic blood pressure in sickle cell anemia; LIHC cis rs12644436 0.896 rs7655253 chr4:88777396 A/C cg06891869 chr4:88767617 MEPE -0.32 -5.95 -0.31 6.79e-9 HIV-1 viral setpoint; LIHC trans rs1005277 0.579 rs1614236 chr10:38502996 C/T cg27523141 chr10:43048294 ZNF37B 0.38 6.37 0.33 6.21e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7187994 0.848 rs34457873 chr16:84782871 T/G cg07647771 chr16:84786436 USP10 -0.33 -6.47 -0.33 3.47e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.58 -0.34 1.75e-10 Gut microbiome composition (summer); LIHC trans rs8073060 0.544 rs17550716 chr17:33893208 A/G cg19694781 chr19:47549865 TMEM160 1.24 12.75 0.57 1.02e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs3749237 0.595 rs3870338 chr3:49557051 A/G cg03060546 chr3:49711283 APEH 0.58 9.63 0.46 1.4e-19 Resting heart rate; LIHC cis rs2404602 0.967 rs7167613 chr15:77041192 C/A cg03037974 chr15:76606532 NA 0.72 13.99 0.6 1.75e-35 Blood metabolite levels; LIHC cis rs2439831 0.850 rs9944216 chr15:44160773 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.69 -9.54 -0.46 2.72e-19 Lung cancer in ever smokers; LIHC cis rs56235845 0.964 rs4075958 chr5:176784512 A/G cg16006841 chr5:176797999 RGS14 -0.82 -12.49 -0.56 9.47e-30 Hemoglobin concentration;Hematocrit; LIHC cis rs992157 0.835 rs13031757 chr2:219151926 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.78 -12.48 -0.56 9.93e-30 Colorectal cancer; LIHC cis rs16958440 0.867 rs77599321 chr18:44689642 T/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs875971 0.540 rs781152 chr7:65479572 T/A cg18876405 chr7:65276391 NA 0.54 8.84 0.43 5.09e-17 Aortic root size; LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg10096929 chr1:156261403 TMEM79 0.4 6.61 0.34 1.43e-10 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs1538970 0.962 rs9429072 chr1:45810091 C/T cg05343316 chr1:45956843 TESK2 -0.55 -8.35 -0.41 1.7e-15 Platelet count; LIHC cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg21280719 chr6:42927975 GNMT -0.31 -6.96 -0.35 1.75e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs8180040 0.620 rs4683322 chr3:47093189 T/C cg16586182 chr3:47516702 SCAP -0.48 -8.69 -0.43 1.57e-16 Colorectal cancer; LIHC cis rs6446731 0.734 rs7675084 chr4:3273908 C/T cg06533319 chr4:3265114 C4orf44 -0.33 -6.28 -0.32 1.02e-9 Mean platelet volume; LIHC cis rs9918079 0.560 rs7685083 chr4:15610771 G/A cg16509355 chr4:15471240 CC2D2A 0.46 7.09 0.36 7.8e-12 Obesity-related traits; LIHC cis rs7107174 1.000 rs2450129 chr11:77940385 T/C cg02023728 chr11:77925099 USP35 0.46 8.59 0.42 3.15e-16 Testicular germ cell tumor; LIHC cis rs7589728 0.620 rs76687350 chr2:88473832 G/A cg04511125 chr2:88470314 THNSL2 0.97 9.87 0.47 2.22e-20 Plasma clusterin levels; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg15559938 chr1:206837731 NA 0.42 6.59 0.34 1.67e-10 Metabolic traits; LIHC cis rs896854 0.516 rs12679044 chr8:95891356 C/A cg09323728 chr8:95962352 TP53INP1 -0.31 -6.6 -0.34 1.6e-10 Type 2 diabetes; LIHC cis rs1843834 0.634 rs923901 chr2:225477276 A/T cg22455342 chr2:225449267 CUL3 0.45 6.07 0.31 3.48e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs6879260 1.000 rs7730585 chr5:179733440 T/C cg23221052 chr5:179740743 GFPT2 -0.43 -6.02 -0.31 4.44e-9 Height; LIHC cis rs7584330 0.554 rs77194105 chr2:238436463 T/C cg08992911 chr2:238395768 MLPH 0.55 6.05 0.31 3.84e-9 Prostate cancer; LIHC cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg23205692 chr1:25664452 TMEM50A -0.36 -5.76 -0.3 1.9e-8 Erythrocyte sedimentation rate; LIHC cis rs422249 0.512 rs174568 chr11:61593816 C/T cg27386326 chr11:61587980 NA 0.71 15.2 0.64 3.08e-40 Trans fatty acid levels; LIHC cis rs3762637 1.000 rs9843165 chr3:122131111 G/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC cis rs7829975 0.564 rs2921060 chr8:8317817 G/T cg15556689 chr8:8085844 FLJ10661 -0.5 -7.51 -0.38 5.12e-13 Mood instability; LIHC cis rs4474465 0.688 rs4367973 chr11:78284545 C/A cg27205649 chr11:78285834 NARS2 0.5 7.86 0.39 5.04e-14 Alzheimer's disease (survival time); LIHC cis rs898097 0.812 rs8065641 chr17:80820259 A/G cg15664640 chr17:80829946 TBCD -0.78 -12.82 -0.57 5.52e-31 Breast cancer; LIHC cis rs6570726 0.837 rs636894 chr6:145864122 T/C cg23711669 chr6:146136114 FBXO30 0.53 9.18 0.44 4.13e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs921968 0.643 rs2278529 chr2:219502132 C/T cg02985541 chr2:219472218 PLCD4 0.4 7.29 0.37 2.12e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs11711311 0.911 rs13321446 chr3:113522544 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.49 9.19 0.45 3.88e-18 IgG glycosylation; LIHC trans rs7246657 0.943 rs12981532 chr19:37889280 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs5769765 0.773 rs9616206 chr22:50310847 G/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.46 -0.49 2.03e-22 Schizophrenia; LIHC cis rs11864453 0.826 rs2074627 chr16:72136769 C/T cg01557791 chr16:72042693 DHODH -0.53 -8.55 -0.42 4.26e-16 Fibrinogen levels; LIHC cis rs853679 0.542 rs2295594 chr6:28053097 G/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs3806843 0.766 rs2530239 chr5:140062547 C/T cg19875535 chr5:140030758 IK -0.39 -6.31 -0.32 8.75e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs787274 0.619 rs58643876 chr9:115627285 C/A cg13803584 chr9:115635662 SNX30 -0.6 -7.82 -0.39 6.57e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9393692 0.620 rs9379844 chr6:26291527 A/G cg00631329 chr6:26305371 NA 0.35 5.95 0.31 6.52e-9 Educational attainment; LIHC cis rs11690935 0.632 rs9789538 chr2:172618474 G/C cg13550731 chr2:172543902 DYNC1I2 0.63 11.65 0.53 1.24e-26 Schizophrenia; LIHC cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg25072359 chr17:41440525 NA 0.39 6.29 0.32 9.86e-10 Menopause (age at onset); LIHC cis rs28595532 0.582 rs71608361 chr4:119224081 T/C cg21605333 chr4:119757512 SEC24D 0.8 6.78 0.34 5.13e-11 Cannabis dependence symptom count; LIHC trans rs3780486 0.505 rs10758194 chr9:33157419 G/T cg20290983 chr6:43655470 MRPS18A 0.83 15.23 0.64 2.39e-40 IgG glycosylation; LIHC cis rs7582180 0.629 rs11684516 chr2:100949883 C/A cg14675211 chr2:100938903 LONRF2 0.53 8.42 0.41 1.05e-15 Intelligence (multi-trait analysis); LIHC cis rs6450176 0.857 rs1541680 chr5:53304725 G/A ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.69 -0.62 3.11e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1538970 0.669 rs3219476 chr1:45802670 A/C cg05343316 chr1:45956843 TESK2 -0.53 -7.76 -0.39 1.01e-13 Platelet count; LIHC trans rs875971 0.929 rs12535036 chr7:65964063 G/T cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.09e-10 Aortic root size; LIHC cis rs67478160 0.634 rs2144079 chr14:104258884 C/T cg08213375 chr14:104286397 PPP1R13B 0.53 9.99 0.48 8.39e-21 Schizophrenia; LIHC cis rs4684776 0.867 rs7640175 chr3:11353039 G/A cg00170343 chr3:11313890 ATG7 -0.53 -7.28 -0.37 2.31e-12 Small vessel stroke; LIHC cis rs9309711 0.560 rs6548164 chr2:3472665 C/T cg15506890 chr2:3487001 NA 0.4 5.95 0.31 6.52e-9 Neurofibrillary tangles; LIHC cis rs2243480 0.901 rs3813708 chr7:65305632 C/A cg12463550 chr7:65579703 CRCP 0.7 7.15 0.36 5.32e-12 Diabetic kidney disease; LIHC cis rs17539620 0.624 rs62432737 chr6:154834772 G/A cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC cis rs2115536 0.692 rs8036559 chr15:80170563 C/T cg00225070 chr15:80189496 MTHFS 0.45 7.42 0.37 9.33e-13 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs7412746 0.658 rs3768016 chr1:150809919 T/C cg18016565 chr1:150552671 MCL1 0.54 10.33 0.49 6e-22 Melanoma; LIHC cis rs68170813 0.559 rs3801959 chr7:106955666 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.12e-9 Coronary artery disease; LIHC cis rs4763879 0.739 rs2895988 chr12:9828427 T/G cg26689682 chr12:9723402 NA -0.36 -5.92 -0.3 8.03e-9 Type 1 diabetes; LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.96 -0.31 6.26e-9 Menopause (age at onset); LIHC cis rs2292096 1.000 rs12756996 chr1:200780333 T/C cg11814564 chr1:200748674 CAMSAP1L1 -0.45 -5.92 -0.3 7.95e-9 Epilepsy; LIHC cis rs1371867 0.846 rs1660329 chr8:101304048 G/T cg06636551 chr8:101224915 SPAG1 -0.5 -9.06 -0.44 1.02e-17 Atrioventricular conduction; LIHC cis rs7027203 0.797 rs7870672 chr9:96606693 A/C cg14598338 chr9:96623480 NA -0.33 -6.54 -0.33 2.19e-10 DNA methylation (variation); LIHC cis rs17152411 0.600 rs4962711 chr10:126644482 T/C cg07906193 chr10:126599966 NA -0.31 -6.22 -0.32 1.48e-9 Height; LIHC cis rs9457247 0.967 rs428805 chr6:167403132 C/A cg12798992 chr6:167411361 FGFR1OP 0.6 10.0 0.48 8.15e-21 Crohn's disease; LIHC cis rs9902453 1.000 rs4074170 chr17:28381141 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.73 -0.54 6.15e-27 Coffee consumption (cups per day); LIHC cis rs1892700 0.840 rs111479052 chr21:34866825 A/G cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.97e-8 Educational attainment; LIHC cis rs112158604 1 rs112158604 chr1:150696792 TCTTCTGCAG/T cg13175981 chr1:150552382 MCL1 0.53 8.15 0.4 7.07e-15 Lymphocyte counts; LIHC cis rs9549367 0.713 rs9549691 chr13:113861606 A/C cg18105134 chr13:113819100 PROZ -0.81 -13.57 -0.59 7.51e-34 Platelet distribution width; LIHC cis rs8017423 1.000 rs2184281 chr14:90685923 A/G cg14092571 chr14:90743983 NA 0.4 6.2 0.32 1.65e-9 Mortality in heart failure; LIHC cis rs3008870 0.755 rs2815349 chr1:67472280 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.64 10.76 0.5 1.86e-23 Lymphocyte percentage of white cells; LIHC cis rs61990749 0.597 rs1008988 chr14:78260795 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.55 -0.38 3.94e-13 Fibroblast growth factor basic levels; LIHC cis rs7733403 1 rs7733403 chr5:140154215 A/G cg19875535 chr5:140030758 IK 0.37 6.08 0.31 3.2e-9 Schizophrenia; LIHC cis rs8180040 0.654 rs1466740 chr3:47245883 C/T cg16586182 chr3:47516702 SCAP 0.49 8.67 0.42 1.81e-16 Colorectal cancer; LIHC trans rs3749237 1.000 rs4768 chr3:49758764 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.64 10.1 0.48 3.53e-21 Resting heart rate; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg11905131 chr22:24372483 LOC391322 -0.61 -8.83 -0.43 5.34e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7116495 1.000 rs3814721 chr11:71709272 C/T cg26138937 chr11:71823887 C11orf51 -0.74 -7.47 -0.37 6.83e-13 Severe influenza A (H1N1) infection; LIHC cis rs240764 0.669 rs846800 chr6:101270498 C/G cg09795085 chr6:101329169 ASCC3 0.55 7.41 0.37 9.69e-13 Neuroticism; LIHC cis rs7607369 0.580 rs17573724 chr2:219652141 T/A cg02176678 chr2:219576539 TTLL4 -0.43 -5.73 -0.3 2.26e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7131987 0.903 rs7970390 chr12:29398655 A/G cg05697976 chr12:29376483 FAR2 0.34 7.01 0.35 1.26e-11 QT interval; LIHC cis rs7727544 0.735 rs274558 chr5:131721174 A/G cg24060327 chr5:131705240 SLC22A5 0.58 8.24 0.41 3.7e-15 Blood metabolite levels; LIHC cis rs12701220 0.894 rs2141274 chr7:1034717 G/A cg00990874 chr7:1149470 C7orf50 -0.63 -8.83 -0.43 5.36e-17 Bronchopulmonary dysplasia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02514519 chr11:61348922 SYT7 0.49 7.11 0.36 6.87e-12 Lung function (FEV1/FVC); LIHC cis rs2075371 0.933 rs2544181 chr7:133944934 C/T cg20476274 chr7:133979776 SLC35B4 0.7 11.41 0.53 9.02e-26 Mean platelet volume; LIHC cis rs950169 0.800 rs34302901 chr15:85110943 C/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.53 0.42 4.64e-16 Schizophrenia; LIHC cis rs875971 0.867 rs1002053 chr7:65798545 G/A cg18252515 chr7:66147081 NA 0.43 6.08 0.31 3.2e-9 Aortic root size; LIHC cis rs4407350 1.000 rs1475991 chr22:44923160 T/C cg11695653 chr22:44894386 LDOC1L -0.37 -6.03 -0.31 4.31e-9 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11255230 chr18:60987808 BCL2 0.45 6.66 0.34 1.09e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs12594515 0.694 rs2068294 chr15:45985548 G/T cg01629716 chr15:45996671 NA 0.51 9.3 0.45 1.65e-18 Waist circumference;Weight; LIHC cis rs6466055 0.720 rs35757884 chr7:105020534 G/T cg04380332 chr7:105027541 SRPK2 -0.38 -7.02 -0.35 1.2e-11 Schizophrenia; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg01836096 chr8:145578603 C8ORFK29 0.41 6.21 0.32 1.56e-9 Immature fraction of reticulocytes; LIHC cis rs11758351 0.660 rs11755943 chr6:26211368 A/G cg03854865 chr6:26224070 HIST1H3E 0.56 6.37 0.33 6.27e-10 Gout;Renal underexcretion gout; LIHC cis rs875971 0.540 rs781152 chr7:65479572 T/A cg26939375 chr7:64535504 NA 0.46 6.79 0.34 5.08e-11 Aortic root size; LIHC cis rs17401966 1.000 rs4846208 chr1:10313839 T/C cg19773385 chr1:10388646 KIF1B -0.48 -8.27 -0.41 2.95e-15 Hepatocellular carcinoma; LIHC trans rs1873147 0.569 rs12593531 chr15:63309936 C/G cg00426498 chr17:27507667 MYO18A -0.34 -6.19 -0.32 1.69e-9 Orofacial clefts; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15155463 chr2:71693793 DYSF 0.53 7.04 0.36 1.04e-11 Lung function (FEV1/FVC); LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg21724239 chr8:58056113 NA 0.58 7.56 0.38 3.72e-13 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.15e-9 Menopause (age at onset); LIHC cis rs7954584 0.520 rs1169094 chr12:122465535 A/G cg22168489 chr12:122356033 WDR66 -0.36 -5.94 -0.31 7.04e-9 Mean corpuscular volume; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg02990361 chr1:107599529 PRMT6 0.63 10.37 0.49 4.27e-22 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4474465 0.646 rs10793337 chr11:78285875 A/T cg27205649 chr11:78285834 NARS2 0.5 7.91 0.39 3.58e-14 Alzheimer's disease (survival time); LIHC cis rs61990749 0.597 rs9788540 chr14:78132172 G/C cg21497246 chr14:78225524 SNW1;C14orf178 0.43 6.65 0.34 1.14e-10 Fibroblast growth factor basic levels; LIHC cis rs7769051 1.000 rs73554431 chr6:133129922 T/G cg07930552 chr6:133119739 C6orf192 0.62 6.17 0.32 1.96e-9 Type 2 diabetes nephropathy; LIHC cis rs3096299 0.933 rs3114848 chr16:89452771 G/A cg08822215 chr16:89438651 ANKRD11 -0.44 -6.98 -0.35 1.52e-11 Multiple myeloma (IgH translocation); LIHC cis rs1843834 0.898 rs2015099 chr2:225519915 T/C cg22455342 chr2:225449267 CUL3 0.42 5.98 0.31 5.71e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs4660306 0.961 rs4660867 chr1:45986484 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.67 -0.34 1.02e-10 Homocysteine levels; LIHC cis rs6066825 0.644 rs2092492 chr20:47338650 A/G cg18078177 chr20:47281410 PREX1 0.4 6.49 0.33 2.98e-10 Colorectal cancer; LIHC cis rs2236267 0.693 rs8008120 chr14:88622367 A/C cg02175263 chr14:88627849 NA 0.31 5.94 0.31 6.85e-9 Food antigen IgG levels; LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg12568669 chr8:11666485 FDFT1 -0.3 -6.04 -0.31 3.96e-9 Monocyte count; LIHC cis rs11969893 0.737 rs1854483 chr6:101378117 G/A cg12253828 chr6:101329408 ASCC3 1.04 13.07 0.58 5.89e-32 Economic and political preferences (immigration/crime); LIHC cis rs4819052 0.851 rs2838826 chr21:46655785 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.49 6.58 0.34 1.73e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs17384381 1.000 rs36110608 chr1:85852936 A/C cg16011679 chr1:85725395 C1orf52 0.82 8.6 0.42 3e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs4746818 1.000 rs10733850 chr10:70959617 C/T cg11621586 chr10:70884670 VPS26A 0.79 10.99 0.51 3e-24 Left atrial antero-posterior diameter; LIHC cis rs8141529 0.778 rs7287806 chr22:29213011 G/A cg02153584 chr22:29168773 CCDC117 0.58 9.45 0.45 5.66e-19 Lymphocyte counts; LIHC cis rs6061231 0.837 rs6061235 chr20:60978524 C/G cg06026331 chr20:60912101 LAMA5 0.48 6.44 0.33 4.05e-10 Colorectal cancer; LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg11060661 chr22:24314208 DDT;DDTL 0.61 10.28 0.49 8.74e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3749237 0.595 rs3870338 chr3:49557051 A/G cg07636037 chr3:49044803 WDR6 0.53 8.19 0.4 5.43e-15 Resting heart rate; LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.13 0.55 2.03e-28 Height; LIHC cis rs9549367 0.789 rs9549711 chr13:113900557 C/T cg00898013 chr13:113819073 PROZ -0.42 -7.18 -0.36 4.24e-12 Platelet distribution width; LIHC cis rs12744310 0.887 rs35410722 chr1:41796264 C/T cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.77e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1062177 1.000 rs2964584 chr5:151142878 T/C cg00977110 chr5:151150581 G3BP1 0.56 7.12 0.36 6.36e-12 Preschool internalizing problems; LIHC cis rs2708977 1.000 rs2708977 chr2:97230074 G/A cg01950434 chr2:97203154 ARID5A -0.52 -7.91 -0.39 3.62e-14 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC trans rs1902066 0.604 rs2444820 chr6:81379924 C/G cg07248951 chr1:36397042 EIF2C3 0.4 6.05 0.31 3.81e-9 Breast cancer; LIHC cis rs1185460 0.967 rs2509121 chr11:118928253 C/T cg23280166 chr11:118938394 VPS11 0.59 7.92 0.39 3.42e-14 Coronary artery disease; LIHC cis rs7927592 0.913 rs3740629 chr11:68343593 C/T cg16797656 chr11:68205561 LRP5 0.5 7.8 0.39 7.44e-14 Total body bone mineral density; LIHC cis rs3812831 0.695 rs7983872 chr13:114944781 T/G cg06611532 chr13:114900021 NA 0.41 7.55 0.38 4.03e-13 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04619800 chr15:83654972 FAM103A1 0.48 6.96 0.35 1.75e-11 Lung function (FEV1/FVC); LIHC cis rs8017423 1.000 rs10129210 chr14:90668379 G/T cg14092571 chr14:90743983 NA -0.37 -5.81 -0.3 1.47e-8 Mortality in heart failure; LIHC cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg12310025 chr6:25882481 NA -0.44 -6.67 -0.34 1.03e-10 Height; LIHC cis rs1005277 0.579 rs1621040 chr10:38497232 T/C cg25427524 chr10:38739819 LOC399744 -0.75 -15.03 -0.63 1.46e-39 Extrinsic epigenetic age acceleration; LIHC cis rs17685 0.753 rs1639617 chr7:75701728 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs950169 0.887 rs71395453 chr15:85113490 G/C cg17507749 chr15:85114479 UBE2QP1 0.78 8.96 0.44 2.18e-17 Schizophrenia; LIHC cis rs9325144 0.560 rs12424821 chr12:38649951 C/T cg26384229 chr12:38710491 ALG10B -0.59 -8.11 -0.4 8.86e-15 Morning vs. evening chronotype; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg01238044 chr22:24384105 GSTT1 -0.47 -6.42 -0.33 4.59e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20600053 chr18:56806937 SEC11C 0.53 7.25 0.36 2.81e-12 Lung function (FEV1/FVC); LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.748 rs2838322 chr21:44998615 G/C cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.4e-23 Mean corpuscular volume; LIHC cis rs1862618 0.620 rs189695 chr5:56225769 T/C cg12311346 chr5:56204834 C5orf35 -0.46 -6.27 -0.32 1.09e-9 Initial pursuit acceleration; LIHC cis rs6570726 0.791 rs1280275 chr6:145892402 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.27 0.32 1.07e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs36051895 0.623 rs11506668 chr9:5252789 C/T cg02405213 chr9:5042618 JAK2 -0.62 -9.88 -0.47 2.05e-20 Pediatric autoimmune diseases; LIHC cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg12751644 chr20:60527061 NA -0.35 -5.81 -0.3 1.44e-8 Body mass index; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.93 0.63 3.62e-39 Prudent dietary pattern; LIHC cis rs6831352 0.918 rs28987088 chr4:100059139 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7613875 0.580 rs3774745 chr3:50204745 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.49 -6.63 -0.34 1.3100000000000001e-10 Body mass index; LIHC cis rs7666738 1.000 rs7666738 chr4:98968077 C/T cg05340658 chr4:99064831 C4orf37 0.67 11.5 0.53 4.43e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg03517284 chr6:25882590 NA -0.62 -8.77 -0.43 8.61e-17 Blood metabolite levels; LIHC cis rs6121246 0.567 rs6060249 chr20:30190944 G/A cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs875971 0.545 rs316306 chr7:65618674 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.37 -7.5 -0.38 5.5e-13 Aortic root size; LIHC cis rs919433 0.890 rs979020 chr2:198169749 T/C cg10820045 chr2:198174542 NA -0.59 -9.87 -0.47 2.2e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6598955 0.543 rs881578 chr1:26536141 G/A cg04990556 chr1:26633338 UBXN11 0.77 11.14 0.52 8.36e-25 Obesity-related traits; LIHC cis rs4700695 0.534 rs153373 chr5:65426159 G/A cg21114390 chr5:65439923 SFRS12 -0.52 -5.89 -0.3 9.12e-9 Facial morphology (factor 19); LIHC cis rs9399135 0.967 rs6915770 chr6:135369214 G/A cg22676075 chr6:135203613 NA 0.41 6.59 0.34 1.66e-10 Red blood cell count; LIHC cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg13397359 chr6:42928475 GNMT 0.68 9.79 0.47 4.15e-20 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.69 -11.75 -0.54 5.31e-27 Menarche (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25561913 chr10:77161129 ZNF503;C10orf41 0.49 6.73 0.34 7.28e-11 Lung function (FEV1/FVC); LIHC cis rs1552244 0.572 rs57268864 chr3:10164233 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.18 -0.48 1.91e-21 Alzheimer's disease; LIHC cis rs208520 1.000 rs208536 chr6:66963440 T/C cg07460842 chr6:66804631 NA -0.65 -7.0 -0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg04234412 chr22:24373322 LOC391322 -0.76 -11.71 -0.53 7.35e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs77669868 0.703 rs61904685 chr11:114072659 G/A cg01914181 chr11:114070210 ZBTB16 0.52 6.26 0.32 1.15e-9 Monocyte percentage of white cells; LIHC cis rs56011263 0.687 rs4690186 chr4:703607 G/A cg17689763 chr4:710664 PCGF3 -0.72 -10.11 -0.48 3.44e-21 White blood cell count; LIHC cis rs1799949 0.965 rs4239149 chr17:41328095 A/G cg25072359 chr17:41440525 NA -0.4 -6.4 -0.33 5.27e-10 Menopause (age at onset); LIHC cis rs992157 0.585 rs62182795 chr2:219100202 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.22 -0.55 9.39e-29 Colorectal cancer; LIHC cis rs244293 0.965 rs2529507 chr17:53181272 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs559928 0.597 rs2096706 chr11:63924446 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.73 6.53 0.33 2.32e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs8062405 0.755 rs4788080 chr16:28558081 C/T cg07451762 chr16:28383216 NA 0.39 7.05 0.36 9.95e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05935374 chr11:82782929 RAB30 0.45 6.93 0.35 2.04e-11 Cognitive function; LIHC cis rs4243830 0.850 rs7540913 chr1:6581877 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.65 -8.3 -0.41 2.44e-15 Body mass index; LIHC trans rs7618501 0.521 rs55692411 chr3:49911155 G/A cg21659725 chr3:3221576 CRBN 0.57 8.16 0.4 6.63e-15 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17022488 chr1:29462399 NA -0.46 -6.6 -0.34 1.59e-10 Lung function (FEV1/FVC); LIHC cis rs2806561 0.765 rs2806565 chr1:23507068 A/G cg12483005 chr1:23474871 LUZP1 0.46 7.28 0.37 2.37e-12 Height; LIHC cis rs2274273 0.967 rs1009978 chr14:55603061 C/G cg04306507 chr14:55594613 LGALS3 0.33 6.41 0.33 4.92e-10 Protein biomarker; LIHC cis rs74181299 0.571 rs6728523 chr2:65282708 G/C cg05010058 chr2:65284262 CEP68 0.37 5.96 0.31 6.35e-9 Pulse pressure; LIHC cis rs1005277 0.579 rs2505240 chr10:38442419 G/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.95 -0.31 6.69e-9 Extrinsic epigenetic age acceleration; LIHC cis rs72627123 0.582 rs62005102 chr14:74500586 T/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.47 6.22 0.32 1.43e-9 Morning vs. evening chronotype; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23642001 chr8:67025419 NA 0.46 6.08 0.31 3.2e-9 Lung function (FEV1/FVC); LIHC cis rs8180040 0.764 rs2132173 chr3:47247060 C/T cg02527881 chr3:46936655 PTH1R 0.31 6.1 0.31 2.93e-9 Colorectal cancer; LIHC cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg27286337 chr10:134555280 INPP5A 0.89 12.6 0.56 3.52e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg05277466 chr16:88082055 BANP 0.38 6.05 0.31 3.7e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs61440199 0.786 rs73818813 chr3:20148085 C/T cg00235661 chr3:20228976 SGOL1 -0.41 -5.82 -0.3 1.35e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs9911578 1.000 rs302859 chr17:56693132 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs8108269 0.956 rs8107527 chr19:46158417 G/A cg13320842 chr19:46175254 GIPR 0.41 7.74 0.39 1.16e-13 Type 2 diabetes; LIHC cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg27170947 chr2:26402098 FAM59B -0.67 -8.3 -0.41 2.49e-15 Gut microbiome composition (summer); LIHC trans rs7618501 0.602 rs10049087 chr3:50123417 A/G cg21659725 chr3:3221576 CRBN -0.72 -11.53 -0.53 3.33e-26 Intelligence (multi-trait analysis); LIHC cis rs17376456 0.877 rs28575883 chr5:93346035 T/C cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.53e-21 Diabetic retinopathy; LIHC cis rs17685 0.672 rs56343450 chr7:75796235 C/T cg16684958 chr7:75615977 POR 0.52 8.59 0.42 3.22e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg18306943 chr3:40428807 ENTPD3 0.42 7.24 0.36 2.94e-12 Renal cell carcinoma; LIHC cis rs9309473 0.950 rs73947808 chr2:73721250 A/C cg20560298 chr2:73613845 ALMS1 -0.53 -5.93 -0.31 7.35e-9 Metabolite levels; LIHC cis rs11112613 0.713 rs60865625 chr12:105940256 A/C cg03607813 chr12:105948248 NA 0.65 12.56 0.56 5.03e-30 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs8022179 0.580 rs8013228 chr14:103842650 A/G cg17675199 chr6:35436792 RPL10A 0.37 7.39 0.37 1.11e-12 Monocyte count; LIHC cis rs6424115 1.000 rs34477640 chr1:24154067 T/C cg15997130 chr1:24165203 NA -0.47 -9.62 -0.46 1.55e-19 Immature fraction of reticulocytes; LIHC cis rs1707322 0.827 rs6683274 chr1:46241638 T/G cg06784218 chr1:46089804 CCDC17 0.4 6.94 0.35 1.93e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 0.522 rs1617484 chr7:65463095 G/A cg18876405 chr7:65276391 NA 0.48 8.13 0.4 8.02e-15 Aortic root size; LIHC cis rs72781680 0.948 rs72781652 chr2:24213754 G/A cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs9311474 0.607 rs4234633 chr3:52557038 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 8.78 0.43 7.81e-17 Electroencephalogram traits; LIHC cis rs7772486 0.790 rs6924159 chr6:146267873 A/G cg23711669 chr6:146136114 FBXO30 -0.71 -12.5 -0.56 8.37e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs17685 0.633 rs3801471 chr7:75696188 T/G cg16684958 chr7:75615977 POR 0.52 8.69 0.43 1.48e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs1865721 0.804 rs72977816 chr18:73146779 A/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.86 -0.39 4.96e-14 Intelligence; LIHC cis rs6089829 0.962 rs7273930 chr20:61666017 G/A cg03213289 chr20:61660250 NA 0.51 8.98 0.44 1.86e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs2425143 1.000 rs6058304 chr20:34299851 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.65 0.38 2e-13 Bipolar disorder; LIHC cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg06238570 chr21:40685208 BRWD1 -0.56 -6.74 -0.34 6.88e-11 Cognitive function; LIHC cis rs4253772 0.591 rs6007732 chr22:46652303 A/T cg09491104 chr22:46646882 C22orf40 -0.6 -6.97 -0.35 1.63e-11 LDL cholesterol;Cholesterol, total; LIHC cis rs10504229 0.610 rs7840469 chr8:58146992 C/T cg08219700 chr8:58056026 NA 0.43 6.11 0.31 2.73e-9 Developmental language disorder (linguistic errors); LIHC cis rs7089973 0.604 rs11196936 chr10:116588630 C/T cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs8060686 0.545 rs76495028 chr16:68177036 G/C cg09835421 chr16:68378352 PRMT7 -0.54 -6.05 -0.31 3.78e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs6882046 0.513 rs1081158 chr5:88004616 C/T cg22951263 chr5:87985283 NA -0.36 -6.53 -0.33 2.33e-10 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs7520050 0.966 rs11579634 chr1:46466391 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 -0.41 -5.8 -0.3 1.47e-8 Red blood cell count;Reticulocyte count; LIHC cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs7116495 0.609 rs17161751 chr11:71688347 G/A cg10381502 chr11:71823885 C11orf51 1.02 8.51 0.42 5.38e-16 Severe influenza A (H1N1) infection; LIHC cis rs17125944 0.505 rs75661138 chr14:53259262 G/A cg00686598 chr14:53173677 PSMC6 1.32 16.14 0.66 5.8e-44 Alzheimer's disease (late onset); LIHC cis rs921968 0.565 rs6708192 chr2:219592227 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.46 -0.33 3.5e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs17095355 1.000 rs4565840 chr10:111717140 A/G cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.81 -0.3 1.43e-8 Biliary atresia; LIHC trans rs2270927 0.510 rs2937749 chr5:75571564 T/G cg13563193 chr19:33072644 PDCD5 0.89 8.27 0.41 3.09e-15 Mean corpuscular volume; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg20365580 chr8:22414115 SORBS3 -0.33 -6.61 -0.34 1.49e-10 Monocyte count; LIHC cis rs7647973 0.626 rs4855845 chr3:49687043 T/C cg03060546 chr3:49711283 APEH 0.6 6.94 0.35 1.98e-11 Menarche (age at onset); LIHC cis rs17376456 0.825 rs10038831 chr5:93124115 C/T cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs2153535 0.580 rs6921964 chr6:8446395 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.5 0.42 6e-16 Motion sickness; LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg02782426 chr3:40428986 ENTPD3 0.34 6.41 0.33 4.69e-10 Renal cell carcinoma; LIHC cis rs11608355 0.515 rs2287184 chr12:109970251 T/C cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs796364 0.760 rs56285751 chr2:200919836 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs757110 0.866 rs5215 chr11:17408630 C/T cg15432903 chr11:17409602 KCNJ11 0.68 11.01 0.51 2.36e-24 Type 2 diabetes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19482537 chr5:156692823 CYFIP2 0.48 6.48 0.33 3.19e-10 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg05590025 chr7:65112418 INTS4L2 0.58 6.63 0.34 1.34e-10 Diabetic kidney disease; LIHC cis rs7027203 0.828 rs7037960 chr9:96584028 G/A cg13679303 chr9:96623674 NA -0.29 -6.61 -0.34 1.45e-10 DNA methylation (variation); LIHC cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.46 0.53 5.8e-26 Colorectal cancer; LIHC cis rs10791097 0.702 rs10894267 chr11:130714861 C/T cg12179176 chr11:130786555 SNX19 -0.6 -9.03 -0.44 1.3e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs74181299 0.571 rs7559813 chr2:65278023 A/G cg05010058 chr2:65284262 CEP68 -0.37 -6.06 -0.31 3.61e-9 Pulse pressure; LIHC cis rs9328573 1.000 rs12440915 chr15:100509915 G/A cg09918751 chr15:100517450 ADAMTS17 -0.47 -7.09 -0.36 7.78e-12 Urate levels in lean individuals; LIHC trans rs1005277 0.579 rs2474599 chr10:38438939 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs2354432 1.000 rs10900325 chr1:146692174 C/T cg25205988 chr1:146714368 CHD1L -0.91 -12.37 -0.56 2.63e-29 Mitochondrial DNA levels; LIHC cis rs9640161 0.711 rs60268791 chr7:150023800 G/T cg10018233 chr7:150070692 REPIN1 0.57 9.62 0.46 1.5700000000000001e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs4474465 1.000 rs10899508 chr11:78170708 T/G cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs722599 0.748 rs741096 chr14:75351487 A/G cg08847533 chr14:75593920 NEK9 -0.55 -8.87 -0.43 4.2e-17 IgG glycosylation; LIHC trans rs1814175 0.817 rs80244685 chr11:49763292 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.3e-11 Height; LIHC cis rs1008375 0.932 rs6841784 chr4:17626418 G/A cg02297831 chr4:17616191 MED28 0.43 6.16 0.32 2.03e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10464366 0.544 rs12668821 chr7:39167846 T/A cg18850127 chr7:39170497 POU6F2 0.46 8.09 0.4 1.04e-14 IgG glycosylation; LIHC cis rs1144333 0.655 rs79322031 chr1:76391978 C/T cg10523679 chr1:76189770 ACADM 0.46 6.33 0.32 7.79e-10 Attention function in attention deficit hyperactive disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06438815 chr21:46292710 PTTG1IP 0.41 6.24 0.32 1.27e-9 Pancreatic cancer; LIHC cis rs10464366 0.544 rs9639812 chr7:39192058 C/T cg15212455 chr7:39170539 POU6F2 0.46 8.17 0.4 6.03e-15 IgG glycosylation; LIHC cis rs1003719 0.628 rs2835635 chr21:38528866 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.93 -0.51 4.75e-24 Eye color traits; LIHC cis rs36051895 0.659 rs12343867 chr9:5074189 T/C cg02405213 chr9:5042618 JAK2 -0.68 -11.81 -0.54 3.05e-27 Pediatric autoimmune diseases; LIHC cis rs969413 0.535 rs8077394 chr17:79258787 A/G cg05353290 chr17:79219831 SLC38A10 0.39 5.96 0.31 6.42e-9 Frontotemporal dementia; LIHC cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg07424592 chr7:64974309 NA 0.74 8.56 0.42 3.98e-16 Diabetic kidney disease; LIHC cis rs11023332 0.617 rs1451678 chr11:14781621 A/G cg19336497 chr11:14380999 RRAS2 -0.35 -6.18 -0.32 1.77e-9 Adiponectin levels;Vitamin D levels; LIHC cis rs10791097 0.694 rs7926167 chr11:130745045 T/C cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1348850 0.914 rs10170546 chr2:178248790 C/T cg27490568 chr2:178487706 NA 0.38 6.03 0.31 4.34e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs360929 0.505 rs10010138 chr4:152926202 T/C cg22325059 chr7:6648166 C7orf26 0.58 6.05 0.31 3.71e-9 Volumetric brain MRI; LIHC cis rs10791323 0.604 rs2723598 chr11:133711652 G/A cg06766960 chr11:133703094 NA -0.67 -11.15 -0.52 7.7e-25 Childhood ear infection; LIHC cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg06634786 chr22:41940651 POLR3H -0.7 -7.67 -0.38 1.76e-13 Vitiligo; LIHC cis rs1552244 0.882 rs68153882 chr3:10013110 T/C cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg04317338 chr11:64019027 PLCB3 0.59 8.09 0.4 1.02e-14 Platelet count; LIHC cis rs881375 0.678 rs1930782 chr9:123687905 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 6.08 0.31 3.22e-9 Rheumatoid arthritis; LIHC cis rs2859741 0.967 rs507460 chr1:37493206 C/G cg09363841 chr1:37513479 NA 0.19 6.12 0.31 2.63e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg09074113 chr2:20870087 GDF7 -0.51 -10.26 -0.49 1.01e-21 Abdominal aortic aneurysm; LIHC cis rs2758596 0.850 rs2495270 chr1:156181530 A/G cg24450063 chr1:156163899 SLC25A44 0.91 10.2 0.48 1.73e-21 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs738322 0.967 rs133018 chr22:38572761 G/A cg25457927 chr22:38595422 NA -0.27 -6.72 -0.34 7.83e-11 Cutaneous nevi; LIHC cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg06238570 chr21:40685208 BRWD1 0.61 7.28 0.37 2.36e-12 Cognitive function; LIHC cis rs875971 0.862 rs12698526 chr7:65969105 T/C cg18252515 chr7:66147081 NA -0.46 -6.79 -0.34 4.96e-11 Aortic root size; LIHC cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg03806693 chr22:41940476 POLR3H 1.1 12.88 0.57 3.09e-31 Vitiligo; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.97 -0.35 1.6e-11 Diastolic blood pressure; LIHC cis rs2404602 1.000 rs11072603 chr15:76881138 G/T cg23625390 chr15:77176239 SCAPER 0.37 6.17 0.32 1.94e-9 Blood metabolite levels; LIHC cis rs1957429 0.808 rs6573581 chr14:65331955 G/A cg23373153 chr14:65346875 NA 0.79 11.28 0.52 2.77e-25 Pediatric areal bone mineral density (radius); LIHC cis rs9611565 0.580 rs5758449 chr22:42140160 C/T cg03806693 chr22:41940476 POLR3H 0.78 8.83 0.43 5.47e-17 Vitiligo; LIHC cis rs8180040 0.966 rs57346147 chr3:47410564 C/G cg27129171 chr3:47204927 SETD2 -0.61 -10.23 -0.48 1.29e-21 Colorectal cancer; LIHC cis rs875971 0.545 rs1065265 chr7:65841203 C/T cg11764359 chr7:65958608 NA 0.6 8.43 0.41 1.01e-15 Aortic root size; LIHC cis rs12497850 1.000 rs4858798 chr3:48727112 C/T cg06212747 chr3:49208901 KLHDC8B 0.49 6.39 0.33 5.51e-10 Parkinson's disease; LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg26338869 chr17:61819248 STRADA 0.61 8.92 0.43 2.92e-17 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg07677032 chr17:61819896 STRADA 0.43 6.19 0.32 1.77e-9 Prudent dietary pattern; LIHC cis rs10540 0.730 rs34690033 chr11:492677 G/C cg03352830 chr11:487213 PTDSS2 0.78 6.6 0.34 1.57e-10 Body mass index; LIHC cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg03396347 chr1:1875803 NA -0.46 -8.58 -0.42 3.3e-16 Body mass index; LIHC cis rs4843747 0.671 rs72818577 chr16:88111181 G/A cg07560587 chr16:88016574 BANP 0.35 5.72 0.3 2.27e-8 Menopause (age at onset); LIHC cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg22907277 chr7:1156413 C7orf50 0.58 8.88 0.43 3.91e-17 Longevity;Endometriosis; LIHC cis rs798554 0.836 rs798490 chr7:2801542 C/T cg19346786 chr7:2764209 NA -0.43 -6.6 -0.34 1.61e-10 Height; LIHC cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg22800045 chr5:56110881 MAP3K1 0.67 8.59 0.42 3.12e-16 Initial pursuit acceleration; LIHC cis rs1005277 0.563 rs2505216 chr10:38482830 T/C cg25427524 chr10:38739819 LOC399744 -0.72 -14.26 -0.61 1.58e-36 Extrinsic epigenetic age acceleration; LIHC cis rs709400 0.663 rs62007684 chr14:103894223 T/C cg26031613 chr14:104095156 KLC1 0.79 10.34 0.49 5.46e-22 Body mass index; LIHC cis rs7551222 0.752 rs35270244 chr1:204548416 A/C cg20240347 chr1:204465584 NA -0.32 -6.42 -0.33 4.6e-10 Schizophrenia; LIHC cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.57 9.64 0.46 1.31e-19 Bipolar disorder; LIHC cis rs34779708 0.966 rs10827492 chr10:35429825 A/G cg03585969 chr10:35415529 CREM -0.86 -13.15 -0.58 3e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3812831 0.669 rs7327370 chr13:114946858 A/G cg06611532 chr13:114900021 NA 0.39 6.98 0.35 1.53e-11 Schizophrenia; LIHC cis rs801193 0.935 rs2286683 chr7:66129843 G/A cg14393609 chr7:65229607 NA -0.37 -5.83 -0.3 1.27e-8 Aortic root size; LIHC cis rs9783347 1.000 rs12286683 chr11:18348662 G/T cg15585147 chr11:18324498 HPS5 0.43 6.73 0.34 6.95e-11 Pancreatic cancer; LIHC cis rs3806843 0.518 rs2569188 chr5:140008419 G/A cg09824255 chr5:140014002 CD14 0.29 6.22 0.32 1.46e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs3096299 0.617 rs2353030 chr16:89405827 C/T cg06640241 chr16:89574553 SPG7 -0.51 -8.04 -0.4 1.47e-14 Multiple myeloma (IgH translocation); LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg05025164 chr4:1340916 KIAA1530 0.53 8.15 0.4 7.17e-15 Obesity-related traits; LIHC cis rs2832191 0.935 rs11910316 chr21:30519729 G/A cg08807101 chr21:30365312 RNF160 -0.52 -8.26 -0.41 3.15e-15 Dental caries; LIHC cis rs6500602 0.702 rs6500605 chr16:4502410 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.42 6.06 0.31 3.61e-9 Schizophrenia; LIHC cis rs4586057 0.514 rs7909232 chr10:92651479 G/A cg14313238 chr10:92632228 RPP30 0.36 6.04 0.31 4.12e-9 Economic and political preferences (time); LIHC cis rs7959452 0.532 rs2291005 chr12:69764388 A/G cg22834771 chr12:69754056 YEATS4 -0.53 -9.35 -0.45 1.18e-18 Blood protein levels; LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg26668828 chr6:292823 DUSP22 -0.6 -8.06 -0.4 1.26e-14 Menopause (age at onset); LIHC cis rs1669338 0.588 rs3864050 chr3:3186769 T/C cg16797762 chr3:3221439 CRBN -0.96 -8.6 -0.42 2.98e-16 White matter integrity; LIHC cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.36 0.33 6.36e-10 Schizophrenia; LIHC cis rs1190552 0.739 rs1998421 chr14:102979644 C/T cg10241871 chr14:102965420 TECPR2 -0.47 -7.16 -0.36 5.08e-12 Blood protein levels; LIHC cis rs11718455 0.960 rs13083325 chr3:44005333 T/C cg08738300 chr3:44038990 NA 0.51 8.86 0.43 4.47e-17 Coronary artery disease; LIHC cis rs9911578 1.000 rs12449365 chr17:56600660 C/G cg05425664 chr17:57184151 TRIM37 0.58 8.51 0.42 5.54e-16 Intelligence (multi-trait analysis); LIHC cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg06028808 chr11:68637592 NA 0.43 5.84 0.3 1.21e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs12579753 0.879 rs1986537 chr12:82156475 G/C cg07988820 chr12:82153109 PPFIA2 -0.49 -5.94 -0.31 6.82e-9 Resting heart rate; LIHC cis rs12971120 0.947 rs8084109 chr18:72168312 T/A cg26446133 chr18:72167187 CNDP2 -0.79 -15.83 -0.65 1.03e-42 Refractive error; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13340481 chr17:27275985 PHF12 0.43 6.12 0.31 2.6e-9 Lung function (FEV1/FVC); LIHC cis rs10504229 1.000 rs67096506 chr8:58195655 G/A cg20607798 chr8:58055168 NA 0.59 6.8 0.35 4.58e-11 Developmental language disorder (linguistic errors); LIHC trans rs8073060 0.586 rs225257 chr17:33956625 G/A cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2153535 0.580 rs1577466 chr6:8444192 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.51 0.53 3.97e-26 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00810945 chr16:21964237 UQCRC2 0.45 6.35 0.32 6.76e-10 Pancreatic cancer; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg00280220 chr17:61926910 NA 0.42 6.51 0.33 2.66e-10 Prudent dietary pattern; LIHC cis rs2073300 0.609 rs6137930 chr20:23376732 G/A cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg14393609 chr7:65229607 NA 0.44 6.49 0.33 2.98e-10 Calcium levels; LIHC cis rs4700695 0.719 rs27077 chr5:65445342 C/T cg21114390 chr5:65439923 SFRS12 0.58 8.25 0.41 3.45e-15 Facial morphology (factor 19); LIHC cis rs57502260 0.704 rs41478448 chr11:68181621 A/G cg01657329 chr11:68192670 LRP5 -0.59 -6.65 -0.34 1.19e-10 Total body bone mineral density (age 45-60); LIHC cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs9682041 0.668 rs6784631 chr3:170100476 T/C cg11886554 chr3:170076028 SKIL 1.12 7.93 0.39 3.21e-14 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs7589728 0.925 rs80065975 chr2:88502758 G/A cg07952391 chr2:88470173 THNSL2 0.77 7.15 0.36 5.27e-12 Plasma clusterin levels; LIHC cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg17971929 chr21:40555470 PSMG1 0.86 10.36 0.49 4.56e-22 Cognitive function; LIHC cis rs1691799 0.528 rs1472314 chr12:66788838 C/G cg16791601 chr12:66731901 HELB -0.41 -8.28 -0.41 2.77e-15 White blood cell count (basophil); LIHC cis rs3540 0.533 rs2352601 chr15:91053125 G/A cg22089800 chr15:90895588 ZNF774 -0.56 -8.1 -0.4 1e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs7091068 0.518 rs9633674 chr10:95455431 C/T cg20715218 chr10:95462985 C10orf4 0.58 8.31 0.41 2.23e-15 Urinary tract infection frequency; LIHC cis rs941873 0.835 rs4246944 chr10:81105684 C/T cg11057378 chr10:81107060 PPIF 0.36 5.92 0.3 7.77e-9 Height; LIHC cis rs963731 0.737 rs79756054 chr2:39338998 A/G cg04010122 chr2:39346883 SOS1 0.6 5.92 0.3 7.81e-9 Corticobasal degeneration; LIHC cis rs7172677 0.768 rs72730586 chr15:75354165 G/A cg17294928 chr15:75287854 SCAMP5 0.45 6.42 0.33 4.54e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs933688 0.759 rs1423593 chr5:90752351 T/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.8 15.71 0.65 3.04e-42 Smoking behavior; LIHC cis rs477895 1.000 rs34292685 chr11:64049021 C/T cg04317338 chr11:64019027 PLCB3 0.75 7.71 0.38 1.41e-13 Mean platelet volume; LIHC cis rs4808199 0.842 rs11085259 chr19:19445856 C/T cg03709012 chr19:19516395 GATAD2A 0.99 15.84 0.65 9.42e-43 Nonalcoholic fatty liver disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg22779765 chr14:103369786 TRAF3 0.48 6.86 0.35 3.14e-11 Longevity; LIHC cis rs10503871 0.816 rs3779639 chr8:30407991 A/G cg26383811 chr8:30366931 RBPMS -0.39 -6.58 -0.34 1.73e-10 Metabolite levels (X-11787); LIHC cis rs6582630 0.638 rs10880620 chr12:38517467 A/G cg26384229 chr12:38710491 ALG10B -0.49 -6.85 -0.35 3.49e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs5769765 0.862 rs7410537 chr22:50317330 G/A cg02269571 chr22:50332266 NA -0.66 -8.97 -0.44 2.03e-17 Schizophrenia; LIHC cis rs9814567 1.000 rs9864439 chr3:134298671 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.93 -0.31 7.23e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12602486 1.000 rs78673779 chr17:42217936 G/A cg08193365 chr17:42277699 NA 1.08 7.74 0.39 1.12e-13 Glycated hemoglobin levels; LIHC cis rs4819052 0.851 rs10470246 chr21:46659017 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.52 0.53 3.51e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs67460515 0.926 rs66508859 chr3:160946351 C/T cg17135325 chr3:160939158 NMD3 0.54 7.63 0.38 2.42e-13 Parkinson's disease; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg11070056 chr1:107600091 PRMT6 0.68 11.61 0.53 1.68e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs881375 0.967 rs10435844 chr9:123668199 G/T cg14580859 chr9:123691850 NA 0.39 6.83 0.35 3.96e-11 Rheumatoid arthritis; LIHC cis rs7131987 0.903 rs11050163 chr12:29420398 C/T cg05697976 chr12:29376483 FAR2 0.32 6.65 0.34 1.14e-10 QT interval; LIHC cis rs933688 0.938 rs10063683 chr5:90714595 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.61 0.67 7.88e-46 Smoking behavior; LIHC cis rs2075371 0.933 rs2544201 chr7:133963561 C/G cg20476274 chr7:133979776 SLC35B4 0.73 12.53 0.56 6.85e-30 Mean platelet volume; LIHC cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC trans rs2739330 0.929 rs5751777 chr22:24267047 C/T cg06437703 chr8:37914619 EIF4EBP1 -0.53 -7.96 -0.4 2.51e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7224737 0.956 rs7208907 chr17:40284783 C/T cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs7089973 0.624 rs11196940 chr10:116593791 T/G cg23260525 chr10:116636907 FAM160B1 0.34 6.66 0.34 1.07e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg11764359 chr7:65958608 NA -0.57 -5.92 -0.31 7.72e-9 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25616684 chr1:38478508 UTP11L 0.43 6.09 0.31 3e-9 Lung function (FEV1/FVC); LIHC cis rs950169 0.610 rs34529571 chr15:84691807 A/G cg17507749 chr15:85114479 UBE2QP1 0.67 6.39 0.33 5.38e-10 Schizophrenia; LIHC cis rs9733 0.744 rs2089081 chr1:150800117 T/C cg13175981 chr1:150552382 MCL1 0.45 6.58 0.34 1.81e-10 Tonsillectomy; LIHC cis rs11098499 0.874 rs12502503 chr4:120116255 C/T cg09307838 chr4:120376055 NA 0.52 7.74 0.39 1.16e-13 Corneal astigmatism; LIHC cis rs2832077 0.689 rs2832052 chr21:30130073 G/C cg24692254 chr21:30365293 RNF160 -0.42 -6.46 -0.33 3.65e-10 Cognitive test performance; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg21248554 chr2:27665150 KRTCAP3 -0.43 -5.79 -0.3 1.6e-8 Total body bone mineral density; LIHC cis rs2404602 0.716 rs117129193 chr15:76656803 A/G cg03037974 chr15:76606532 NA 0.8 16.71 0.67 3.06e-46 Blood metabolite levels; LIHC cis rs3790645 1.000 rs396997 chr1:26893067 T/C cg23229016 chr1:26872525 RPS6KA1 0.23 5.75 0.3 1.95e-8 Glucose homeostasis traits; LIHC cis rs7520050 0.843 rs1707334 chr1:46605728 A/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.45 6.79 0.34 5.06e-11 Red blood cell count;Reticulocyte count; LIHC cis rs11098499 0.739 rs7441137 chr4:120133221 G/T cg09307838 chr4:120376055 NA -0.49 -7.54 -0.38 4.38e-13 Corneal astigmatism; LIHC cis rs875971 0.830 rs12673450 chr7:66009220 G/A cg18876405 chr7:65276391 NA 0.32 5.74 0.3 2.06e-8 Aortic root size; LIHC cis rs9470366 0.816 rs1321311 chr6:36622900 C/A cg08179530 chr6:36648295 CDKN1A 0.54 6.71 0.34 8.3e-11 QRS duration; LIHC cis rs35306767 0.953 rs10904583 chr10:983498 T/C cg20503657 chr10:835505 NA 0.87 10.02 0.48 6.8e-21 Eosinophil percentage of granulocytes; LIHC cis rs10847980 0.590 rs12299742 chr12:123323357 T/G cg07706471 chr12:123319906 HIP1R 0.72 8.13 0.4 7.75e-15 Adiponectin levels; LIHC trans rs877282 0.853 rs11253332 chr10:755262 G/C cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg13397359 chr6:42928475 GNMT 0.83 12.12 0.55 2.32e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs72627123 0.867 rs58894370 chr14:74485382 C/T cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.75 0.3 1.97e-8 Morning vs. evening chronotype; LIHC cis rs11030122 0.733 rs10835331 chr11:3957365 C/T cg18678763 chr11:4115507 RRM1 -0.55 -8.25 -0.41 3.39e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs6442522 0.560 rs2255897 chr3:15520677 A/C cg16303742 chr3:15540471 COLQ -0.38 -6.01 -0.31 4.71e-9 Uric acid levels; LIHC cis rs6951245 0.507 rs11976805 chr7:1138716 C/T cg22907277 chr7:1156413 C7orf50 0.67 8.6 0.42 2.99e-16 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6665290 0.904 rs3768425 chr1:227178127 A/G cg10327440 chr1:227177885 CDC42BPA -1.19 -31.54 -0.86 3e-103 Myeloid white cell count; LIHC cis rs2820315 0.505 rs10800792 chr1:201811144 G/A cg06775570 chr1:201857621 SHISA4 0.41 6.93 0.35 2.06e-11 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; LIHC cis rs8180040 0.932 rs11711265 chr3:47558448 T/C cg27129171 chr3:47204927 SETD2 0.54 8.61 0.42 2.62e-16 Colorectal cancer; LIHC cis rs208520 0.690 rs207118 chr6:66788948 T/A cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC cis rs244293 1.000 rs244289 chr17:53231788 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.16 -0.36 4.99e-12 Menarche (age at onset); LIHC trans rs6489882 0.867 rs4767032 chr12:113363077 T/G cg10175203 chr3:128143634 NA 0.39 6.38 0.33 5.72e-10 Chronic lymphocytic leukemia; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.08e-13 Developmental language disorder (linguistic errors); LIHC cis rs425277 1.000 rs262657 chr1:2088577 G/A cg24578937 chr1:2090814 PRKCZ 0.5 9.08 0.44 8.57e-18 Height; LIHC trans rs1864585 0.520 rs17720365 chr8:10679499 C/G cg20373634 chr10:103911536 NOLC1 0.42 6.06 0.31 3.58e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs3112357 1.000 rs3112339 chr7:135381500 G/C cg20392616 chr7:135392013 SLC13A4 0.41 6.81 0.35 4.52e-11 Plantar warts; LIHC trans rs61931739 0.500 rs28692887 chr12:34457075 G/A cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs1008375 0.898 rs61047804 chr4:17593965 G/A cg02297831 chr4:17616191 MED28 0.46 7.1 0.36 7.4e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17102423 0.755 rs8009714 chr14:65573446 G/T cg11161011 chr14:65562177 MAX -0.59 -8.24 -0.41 3.65e-15 Obesity-related traits; LIHC cis rs10503871 0.967 rs2294085 chr8:30436779 C/T cg26383811 chr8:30366931 RBPMS 0.46 8.17 0.4 6.22e-15 Metabolite levels (X-11787); LIHC cis rs62229266 0.572 rs4816518 chr21:37453307 C/T cg12218747 chr21:37451666 NA -0.44 -7.13 -0.36 6e-12 Mitral valve prolapse; LIHC cis rs2839627 0.561 rs8126478 chr21:44318668 C/A cg03543861 chr21:44258195 NA 0.53 7.77 0.39 9.24e-14 Information processing speed; LIHC cis rs924607 0.900 rs1697950 chr5:616890 G/A cg24163568 chr5:669837 TPPP -0.4 -8.49 -0.42 6.5e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7619427 0.643 rs6794506 chr3:44015668 A/G cg24966902 chr3:44043705 NA -0.57 -6.35 -0.32 6.71e-10 Schizophrenia; LIHC cis rs5769765 0.862 rs9616386 chr22:50313179 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs9649465 1.000 rs6963231 chr7:123374766 A/G cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.25e-15 Migraine; LIHC cis rs2439831 0.850 rs16977798 chr15:44151948 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.68 0.43 1.6e-16 Lung cancer in ever smokers; LIHC cis rs9896933 0.832 rs79103992 chr17:80855483 G/A cg20578329 chr17:80767326 TBCD -0.66 -6.32 -0.32 7.94e-10 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg07424592 chr7:64974309 NA -0.82 -9.61 -0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs6835098 1.000 rs10027708 chr4:174083116 T/C cg08422745 chr4:174089978 GALNT7 -0.32 -5.71 -0.3 2.43e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19400876 chr1:54411017 LRRC42;HSPB11 -0.41 -6.48 -0.33 3.13e-10 Calcium levels; LIHC cis rs9649213 0.593 rs2158553 chr7:97951131 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs908922 0.676 rs4112785 chr1:152533115 G/C cg20991723 chr1:152506922 NA 0.59 10.28 0.49 8.92e-22 Hair morphology; LIHC trans rs1945213 0.625 rs7128190 chr11:55858550 A/T cg03929089 chr4:120376271 NA 0.53 6.87 0.35 3.01e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs7589728 0.563 rs80324973 chr2:88447264 T/G cg04511125 chr2:88470314 THNSL2 0.97 9.88 0.47 1.97e-20 Plasma clusterin levels; LIHC cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg08687515 chr19:58661962 ZNF329 0.99 7.82 0.39 6.56e-14 Cholesterol, total; LIHC cis rs2120019 1.000 rs67544533 chr15:75361539 A/G cg06012730 chr15:75315579 PPCDC -0.35 -6.35 -0.32 6.82e-10 Blood trace element (Zn levels); LIHC cis rs1816752 0.837 rs4769355 chr13:25015197 G/A cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC cis rs798554 0.660 rs2644296 chr7:2859061 A/T cg19717773 chr7:2847554 GNA12 -0.41 -7.3 -0.37 2e-12 Height; LIHC cis rs13223928 0.536 rs12700594 chr7:3156701 G/A cg19214707 chr7:3157722 NA 0.45 8.51 0.42 5.45e-16 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs11168351 0.750 rs11168366 chr12:48421773 T/C cg21466736 chr12:48725269 NA 0.58 7.78 0.39 8.42e-14 Bipolar disorder and schizophrenia; LIHC cis rs12451471 0.559 rs12452263 chr17:78079310 T/C cg24585782 chr17:78113791 EIF4A3 -0.42 -5.76 -0.3 1.85e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05288857 chr19:2226551 DOT1L -0.41 -6.34 -0.32 7.06e-10 Calcium levels; LIHC cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg09323728 chr8:95962352 TP53INP1 -0.3 -6.39 -0.33 5.29e-10 Type 2 diabetes; LIHC cis rs2404602 0.647 rs55778276 chr15:77136590 T/A cg03037974 chr15:76606532 NA -0.59 -9.92 -0.47 1.48e-20 Blood metabolite levels; LIHC cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg10295955 chr4:187884368 NA -0.97 -23.17 -0.78 4.65e-72 Lobe attachment (rater-scored or self-reported); LIHC cis rs34172651 0.517 rs12920774 chr16:24830750 T/C cg00339695 chr16:24857497 SLC5A11 0.73 10.29 0.49 8.17e-22 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg07061783 chr6:25882402 NA 0.63 8.11 0.4 9.29e-15 Blood metabolite levels; LIHC cis rs11583043 0.918 rs3850453 chr1:101408933 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.42 0.41 1.07e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2153535 0.601 rs330105 chr6:8543981 A/C cg23788917 chr6:8435910 SLC35B3 0.61 8.51 0.42 5.68e-16 Motion sickness; LIHC cis rs34172651 0.517 rs11639856 chr16:24788645 A/T cg00339695 chr16:24857497 SLC5A11 -0.6 -8.83 -0.43 5.45e-17 Intelligence (multi-trait analysis); LIHC cis rs9326248 0.954 rs4938349 chr11:117021923 C/T cg26566898 chr11:117069891 TAGLN 0.48 7.64 0.38 2.19e-13 Blood protein levels; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.71 -0.3 2.45e-8 Total body bone mineral density; LIHC trans rs9914544 0.545 rs9912713 chr17:18771145 G/A cg21372672 chr17:16614065 CCDC144A -0.28 -6.75 -0.34 6.53e-11 Educational attainment (years of education); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg18649979 chr19:21688263 ZNF429 -0.42 -6.62 -0.34 1.43e-10 Bilirubin levels; LIHC cis rs4650994 0.593 rs12096732 chr1:178523164 C/T cg05350800 chr1:178550844 NA -0.34 -7.39 -0.37 1.13e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7843479 0.965 rs11785657 chr8:21859485 G/A cg17168535 chr8:21777572 XPO7 0.39 6.26 0.32 1.18e-9 Mean corpuscular volume; LIHC cis rs7116495 1.000 rs11235440 chr11:71826644 A/G cg10381502 chr11:71823885 C11orf51 0.55 5.91 0.3 8.06e-9 Severe influenza A (H1N1) infection; LIHC cis rs965469 1.000 rs6037535 chr20:3270621 C/T cg25506879 chr20:3388711 C20orf194 -0.6 -6.88 -0.35 2.84e-11 IFN-related cytopenia; LIHC cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg06697600 chr4:7070879 GRPEL1 -0.65 -10.32 -0.49 6.5600000000000005e-22 Monocyte percentage of white cells; LIHC cis rs1062177 0.756 rs2964592 chr5:151115688 A/G cg00977110 chr5:151150581 G3BP1 -0.56 -7.17 -0.36 4.52e-12 Preschool internalizing problems; LIHC cis rs4819052 0.851 rs9979545 chr21:46679805 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.59 0.38 3.09e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs858239 0.712 rs199650 chr7:23367189 C/T cg00469287 chr7:23338798 C7orf30 -0.47 -6.29 -0.32 9.52e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2257205 0.667 rs9912325 chr17:56873934 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.61 -0.34 1.5e-10 Pancreatic cancer; LIHC cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg07061783 chr6:25882402 NA 0.66 8.45 0.42 8.25e-16 Blood metabolite levels; LIHC cis rs2228479 0.850 rs17232910 chr16:89839766 G/C cg00800038 chr16:89945340 TCF25 -0.63 -9.49 -0.46 4.05e-19 Skin colour saturation; LIHC cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg05665937 chr4:1216051 CTBP1 0.44 5.81 0.3 1.44e-8 Obesity-related traits; LIHC cis rs4700695 0.719 rs27586 chr5:65445873 G/A cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.46e-15 Facial morphology (factor 19); LIHC cis rs12477438 0.501 rs1133977 chr2:99741984 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.82 -13.72 -0.6 1.94e-34 Chronic sinus infection; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12841375 chr6:52929709 FBXO9 0.41 6.4 0.33 5.21e-10 Cognitive function; LIHC cis rs12086130 0.892 rs72906845 chr1:51491469 G/T cg07174182 chr1:51127561 FAF1 -0.88 -9.84 -0.47 2.7e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs595982 0.559 rs4802516 chr19:49366170 T/C cg21252483 chr19:49399788 TULP2 -0.91 -10.19 -0.48 1.8e-21 Red cell distribution width; LIHC cis rs12220238 1.000 rs10824114 chr10:75970503 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.54 0.33 2.25e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs734999 0.545 rs7368105 chr1:2556548 C/T cg18854424 chr1:2615690 NA 0.34 7.4 0.37 1.09e-12 Ulcerative colitis; LIHC cis rs6977660 1.000 rs6973890 chr7:19820497 T/C cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs9916302 0.706 rs903507 chr17:37726423 A/G cg07936489 chr17:37558343 FBXL20 -0.84 -11.95 -0.54 9.7e-28 Glomerular filtration rate (creatinine); LIHC cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.74 -0.47 5.88e-20 Initial pursuit acceleration; LIHC cis rs8177179 0.967 rs4994581 chr3:133437563 T/C cg16262614 chr3:133464971 TF 0.45 10.22 0.48 1.46e-21 Iron status biomarkers (transferrin levels); LIHC cis rs6840360 0.615 rs1962910 chr4:152479392 T/A cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs1008375 0.932 rs9884565 chr4:17655096 A/G cg02297831 chr4:17616191 MED28 0.48 7.6 0.38 2.91e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9649213 0.574 rs17436977 chr7:97883459 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.41 -6.24 -0.32 1.27e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg06481639 chr22:41940642 POLR3H -0.71 -7.07 -0.36 8.67e-12 Vitiligo; LIHC cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 12.63 0.56 2.73e-30 Alzheimer's disease; LIHC cis rs12477438 0.520 rs2516829 chr2:99773201 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.55 0.64 1.25e-41 Chronic sinus infection; LIHC cis rs1348850 0.526 rs4243389 chr2:178379783 G/C cg27490568 chr2:178487706 NA 0.97 11.03 0.51 2.11e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10751667 0.643 rs10902237 chr11:944801 C/A ch.11.42038R chr11:967971 AP2A2 0.54 9.86 0.47 2.46e-20 Alzheimer's disease (late onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02006803 chr2:128990870 NA -0.42 -6.96 -0.35 1.79e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6570726 0.620 rs12201226 chr6:145913419 A/T cg23711669 chr6:146136114 FBXO30 0.63 9.1 0.44 7.36e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs1664789 1.000 rs1694066 chr5:53282535 C/G ch.5.1024479R chr5:53302184 ARL15 0.53 8.47 0.42 7.55e-16 Waist circumference adjusted for body mass index; LIHC cis rs6967414 0.786 rs6463578 chr7:6753050 C/A cg00387323 chr7:6746715 ZNF12 0.64 7.01 0.35 1.29e-11 Hematocrit;Hemoglobin concentration; LIHC cis rs6088590 0.965 rs910869 chr20:33292777 C/T cg08999081 chr20:33150536 PIGU 0.39 6.07 0.31 3.45e-9 Coronary artery disease; LIHC cis rs2439831 0.867 rs2255440 chr15:43830467 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.7 11.1 0.51 1.16e-24 Lung cancer in ever smokers; LIHC cis rs8078723 0.966 rs2227322 chr17:38171668 C/G cg17467752 chr17:38218738 THRA 0.74 13.45 0.59 2.14e-33 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs11630290 0.592 rs1017531 chr15:64158650 G/A cg12036633 chr15:63758958 NA 0.63 6.81 0.35 4.47e-11 Iris characteristics; LIHC cis rs8017423 0.904 rs7147212 chr14:90697809 A/C cg14092571 chr14:90743983 NA -0.38 -5.94 -0.31 7.01e-9 Mortality in heart failure; LIHC cis rs10744422 1.000 rs7138398 chr12:123341833 G/C cg18912006 chr12:123335444 HIP1R -0.64 -7.69 -0.38 1.55e-13 Schizophrenia; LIHC cis rs17818399 0.926 rs35682608 chr2:46836542 A/T cg02822958 chr2:46747628 ATP6V1E2 0.46 6.77 0.34 5.64e-11 Height; LIHC cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg00684032 chr4:1343700 KIAA1530 -0.5 -7.35 -0.37 1.44e-12 Obesity-related traits; LIHC cis rs6782228 0.675 rs6806687 chr3:128391789 C/T cg16766828 chr3:128327626 NA 0.42 6.68 0.34 9.83e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7264396 0.570 rs6060717 chr20:34544647 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.59 -0.5 7.31e-23 Total cholesterol levels; LIHC cis rs3096299 0.900 rs3114867 chr16:89428967 A/C cg02187348 chr16:89574699 SPG7 0.47 7.06 0.36 9.58e-12 Multiple myeloma (IgH translocation); LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1580019 0.563 rs13244332 chr7:32537679 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 26.45 0.82 1.07e-84 Cognitive ability; LIHC cis rs1371867 0.846 rs1660353 chr8:101250907 C/T cg06636551 chr8:101224915 SPAG1 0.48 9.13 0.44 6.29e-18 Atrioventricular conduction; LIHC cis rs7618501 0.633 rs4688755 chr3:50064424 G/A cg24110177 chr3:50126178 RBM5 0.48 7.78 0.39 8.46e-14 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.966 rs6661910 chr1:46290632 A/T cg03146154 chr1:46216737 IPP -0.39 -6.51 -0.33 2.74e-10 Red blood cell count;Reticulocyte count; LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs6545883 0.894 rs1186703 chr2:61672965 A/C cg14146966 chr2:61757674 XPO1 0.45 7.77 0.39 9.17e-14 Tuberculosis; LIHC cis rs1707322 1.000 rs4660331 chr1:46458783 A/C cg06784218 chr1:46089804 CCDC17 0.38 6.92 0.35 2.18e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11628318 0.508 rs3950014 chr14:103069889 G/A cg12046867 chr14:103022105 NA -0.48 -6.94 -0.35 1.94e-11 Platelet count; LIHC cis rs2303745 0.622 rs1864113 chr19:17393504 G/C cg10664184 chr19:17420304 DDA1 0.45 5.73 0.3 2.25e-8 Systemic lupus erythematosus; LIHC cis rs916888 0.821 rs199499 chr17:44865498 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.72 5.82 0.3 1.35e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg11645453 chr3:52864694 ITIH4 0.21 5.84 0.3 1.23e-8 Bipolar disorder; LIHC cis rs763121 0.785 rs5757199 chr22:39040617 T/G cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs1008375 1.000 rs12507142 chr4:17656103 A/G cg02297831 chr4:17616191 MED28 0.5 7.64 0.38 2.17e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1568889 0.838 rs7933991 chr11:28059761 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 13.84 0.6 6.88e-35 Bipolar disorder; LIHC trans rs4942242 0.663 rs1472330 chr13:44209628 A/G cg19169023 chr15:41853346 TYRO3 0.51 7.26 0.37 2.59e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs6565180 0.962 rs6565182 chr16:30374381 C/T cg17640201 chr16:30407289 ZNF48 -0.8 -12.61 -0.56 3.44e-30 Tonsillectomy; LIHC cis rs2153535 0.601 rs9502715 chr6:8455709 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs4845570 0.831 rs11588258 chr1:151780728 A/T cg07092448 chr1:151763213 TDRKH -0.68 -7.43 -0.37 8.96e-13 Coronary artery disease; LIHC cis rs4423214 0.879 rs1790330 chr11:71147825 C/T cg05163923 chr11:71159392 DHCR7 -0.61 -8.48 -0.42 6.83e-16 Vitamin D levels; LIHC cis rs778371 0.723 rs283470 chr2:233656918 G/A cg08000102 chr2:233561755 GIGYF2 0.88 15.02 0.63 1.6e-39 Schizophrenia; LIHC cis rs9948 0.708 rs116121826 chr2:97441914 A/G cg01990225 chr2:97406019 LMAN2L -0.72 -6.27 -0.32 1.12e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs62244186 0.773 rs6809116 chr3:44712097 A/C cg25364880 chr3:44379878 C3orf23 0.59 8.11 0.4 9.37e-15 Depressive symptoms; LIHC cis rs9814567 1.000 rs7630874 chr3:134293291 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.25 0.55 7.29e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25048357 chr11:118955763 HMBS 0.48 6.77 0.34 5.77e-11 Lung function (FEV1/FVC); LIHC cis rs763121 0.853 rs6001214 chr22:39149155 C/T cg14440974 chr22:39074834 NA -0.39 -6.29 -0.32 9.77e-10 Menopause (age at onset); LIHC cis rs7534824 0.625 rs12563134 chr1:101468558 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.67 -7.66 -0.38 1.95e-13 Refractive astigmatism; LIHC cis rs739401 0.572 rs739400 chr11:3016520 G/A cg05729581 chr11:3078854 CARS -0.41 -5.75 -0.3 2.03e-8 Longevity; LIHC cis rs9303401 0.659 rs11495824 chr17:56918882 C/A cg25039879 chr17:56429692 SUPT4H1 0.78 8.84 0.43 5.15e-17 Cognitive test performance; LIHC cis rs7582180 0.627 rs6542947 chr2:100999647 C/G cg14675211 chr2:100938903 LONRF2 -0.56 -8.24 -0.41 3.6e-15 Intelligence (multi-trait analysis); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg24247472 chr17:46908838 CALCOCO2 -0.41 -6.24 -0.32 1.26e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6835098 0.828 rs28612521 chr4:174085294 G/A cg27433088 chr4:174089019 GALNT7 0.39 7.18 0.36 4.26e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs4891159 0.757 rs11665018 chr18:74123589 C/T cg24786174 chr18:74118243 ZNF516 -0.77 -14.11 -0.61 5.89e-36 Longevity; LIHC cis rs763121 0.853 rs5995610 chr22:39064681 C/T cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg24549020 chr5:56110836 MAP3K1 0.51 6.37 0.33 5.98e-10 Type 2 diabetes; LIHC cis rs916888 0.821 rs70602 chr17:44859715 T/C cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11112613 0.713 rs55646142 chr12:105949557 G/A cg03607813 chr12:105948248 NA 0.67 13.2 0.58 2.02e-32 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7613875 0.641 rs2624845 chr3:50062437 C/A cg24110177 chr3:50126178 RBM5 0.54 8.75 0.43 9.56e-17 Body mass index; LIHC cis rs2354432 0.607 rs6703847 chr1:146669444 G/A cg25205988 chr1:146714368 CHD1L 0.88 5.94 0.31 7.13e-9 Mitochondrial DNA levels; LIHC cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs11165623 0.792 rs13375510 chr1:96920723 A/G cg10631902 chr5:14652156 NA -0.34 -8.53 -0.42 4.81e-16 Hip circumference;Waist circumference; LIHC cis rs1552244 0.882 rs9812006 chr3:10022658 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.9e-19 Alzheimer's disease; LIHC trans rs116095464 0.558 rs7356696 chr5:284251 A/G cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs7918232 0.941 rs10741128 chr10:27411509 G/A cg14240646 chr10:27532245 ACBD5 -0.66 -6.29 -0.32 9.9e-10 Breast cancer; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.4 -0.33 5e-10 Total body bone mineral density; LIHC cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.13 11.81 0.54 3.21e-27 Platelet count; LIHC cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg22618164 chr12:122356400 WDR66 0.5 7.75 0.39 1.03e-13 Mean corpuscular volume; LIHC cis rs963731 0.579 rs1454220 chr2:39277108 G/A cg04010122 chr2:39346883 SOS1 -0.69 -6.25 -0.32 1.22e-9 Corticobasal degeneration; LIHC cis rs7178375 1.000 rs1474381 chr15:31214991 T/C cg19680485 chr15:31195859 MTMR15 -0.54 -6.05 -0.31 3.73e-9 Hypertriglyceridemia; LIHC cis rs7618501 1.000 rs7618519 chr3:49772708 A/T cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs6565180 0.888 rs12921440 chr16:30408765 C/T cg17640201 chr16:30407289 ZNF48 0.8 13.76 0.6 1.39e-34 Tonsillectomy; LIHC cis rs12701220 0.847 rs10272002 chr7:1047615 A/G cg26769984 chr7:1090371 C7orf50 0.59 7.45 0.37 7.91e-13 Bronchopulmonary dysplasia; LIHC cis rs2274273 0.905 rs17128183 chr14:55579513 C/T cg01864836 chr14:55583639 NA 0.44 8.71 0.43 1.37e-16 Protein biomarker; LIHC cis rs9649213 0.593 rs3779193 chr7:98028466 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.81 -0.3 1.41e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05323904 chr16:691677 FAM195A 0.47 6.91 0.35 2.45e-11 Pancreatic cancer; LIHC cis rs1816752 0.590 rs61947036 chr13:25017682 T/C cg22771759 chr13:24902376 NA 0.31 6.45 0.33 3.75e-10 Obesity-related traits; LIHC cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg00656387 chr3:40428638 ENTPD3 0.51 8.48 0.42 6.9e-16 Renal cell carcinoma; LIHC cis rs4073582 0.595 rs801736 chr11:65928430 A/T cg16950941 chr11:66035639 RAB1B 0.55 8.25 0.41 3.42e-15 Gout; LIHC cis rs11123170 0.650 rs2289897 chr2:113977454 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.47 5.72 0.3 2.33e-8 Renal function-related traits (BUN); LIHC cis rs12744310 0.943 rs35493284 chr1:41755189 T/A cg03962019 chr1:41807865 NA 0.38 6.19 0.32 1.73e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7712401 0.686 rs154509 chr5:122198340 T/A cg18764291 chr5:122110994 SNX2 0.33 5.84 0.3 1.25e-8 Mean platelet volume; LIHC cis rs9354352 1.000 rs9354352 chr6:66696272 T/C cg07460842 chr6:66804631 NA 0.58 9.28 0.45 1.95e-18 Initial pursuit acceleration in psychotic disorders; LIHC cis rs6500602 0.702 rs4786493 chr16:4500122 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.45 7.16 0.36 5.05e-12 Schizophrenia; LIHC cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg06640241 chr16:89574553 SPG7 0.66 10.71 0.5 2.79e-23 Multiple myeloma (IgH translocation); LIHC cis rs11785400 1.000 rs754957 chr8:143746416 A/G cg10596483 chr8:143751796 JRK 0.5 8.19 0.41 5.12e-15 Schizophrenia; LIHC cis rs4474465 0.736 rs11237541 chr11:78261703 T/C cg27205649 chr11:78285834 NARS2 0.44 6.77 0.34 5.56e-11 Alzheimer's disease (survival time); LIHC cis rs9918079 0.560 rs10008975 chr4:15624571 C/T cg24225360 chr4:15471699 CC2D2A -0.39 -6.19 -0.32 1.71e-9 Obesity-related traits; LIHC cis rs17125944 0.556 rs1952088 chr14:53319832 A/C cg00686598 chr14:53173677 PSMC6 -0.81 -9.47 -0.46 4.7e-19 Alzheimer's disease (late onset); LIHC cis rs11690935 1.000 rs12053003 chr2:172537350 A/C cg13550731 chr2:172543902 DYNC1I2 0.92 17.64 0.69 5.57e-50 Schizophrenia; LIHC cis rs3762637 0.943 rs10222564 chr3:122266336 T/C cg24169773 chr3:122142474 KPNA1 -0.44 -8.73 -0.43 1.11e-16 LDL cholesterol levels; LIHC cis rs2070488 0.766 rs6808093 chr3:38498160 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.76 12.75 0.57 1.01e-30 Electrocardiographic conduction measures; LIHC cis rs655641 1.000 rs588076 chr11:85691662 C/G cg09030501 chr11:85779252 PICALM 0.54 6.36 0.33 6.51e-10 Platelet count; LIHC cis rs826838 0.967 rs2069211 chr12:39128892 C/T cg13010199 chr12:38710504 ALG10B -0.41 -5.77 -0.3 1.79e-8 Heart rate; LIHC cis rs3096299 0.606 rs2965946 chr16:89516612 T/C cg02187348 chr16:89574699 SPG7 0.47 6.17 0.32 1.88e-9 Multiple myeloma (IgH translocation); LIHC cis rs9916302 0.665 rs4795369 chr17:37609120 G/A cg00129232 chr17:37814104 STARD3 -0.4 -6.45 -0.33 3.86e-10 Glomerular filtration rate (creatinine); LIHC trans rs6598955 0.671 rs7550997 chr1:26596080 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.76 -8.53 -0.42 4.81e-16 Obesity-related traits; LIHC cis rs9388451 0.531 rs9321057 chr6:126156943 G/A cg05901451 chr6:126070800 HEY2 -0.44 -7.59 -0.38 3.03e-13 Brugada syndrome; LIHC cis rs3741404 0.583 rs640999 chr11:63869425 C/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.67 10.83 0.51 1.04e-23 Platelet count; LIHC cis rs765787 0.530 rs11855435 chr15:45522117 G/A cg24006582 chr15:45444508 DUOX1 -0.5 -7.26 -0.37 2.56e-12 Uric acid levels; LIHC cis rs4555082 0.874 rs2015978 chr14:105720134 G/C cg13114125 chr14:105738426 BRF1 -0.72 -9.35 -0.45 1.21e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs875971 0.965 rs6971509 chr7:65714970 G/T cg11764359 chr7:65958608 NA -0.89 -15.52 -0.64 1.66e-41 Aortic root size; LIHC cis rs2070488 0.896 rs11914389 chr3:38527215 T/C cg24069376 chr3:38537580 EXOG 0.41 7.53 0.38 4.67e-13 Electrocardiographic conduction measures; LIHC cis rs7659604 0.540 rs28615388 chr4:122678418 C/T cg19671926 chr4:122722719 EXOSC9 0.47 7.0 0.35 1.39e-11 Type 2 diabetes; LIHC cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.61e-12 Bipolar disorder; LIHC cis rs7833790 0.660 rs10091077 chr8:82705464 A/G cg02079420 chr8:82753780 SNX16 0.34 6.19 0.32 1.77e-9 Diastolic blood pressure; LIHC cis rs9457247 0.529 rs6907666 chr6:167523395 A/G cg23791538 chr6:167370224 RNASET2 0.5 8.17 0.4 6e-15 Crohn's disease; LIHC cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg03351412 chr1:154909251 PMVK 0.69 10.14 0.48 2.7e-21 Prostate cancer; LIHC cis rs4076764 1.000 rs4076764 chr1:163441286 A/G cg24596788 chr1:163392923 NA -0.24 -7.42 -0.37 9.47e-13 Motion sickness; LIHC cis rs7249142 0.527 rs12975096 chr19:19279409 G/T cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.43 -7.06 -0.36 9.29e-12 IgG glycosylation; LIHC cis rs7872515 0.838 rs6479403 chr9:94829156 A/G cg01248375 chr9:94877805 SPTLC1 0.53 7.89 0.39 4.11e-14 Bipolar disorder and schizophrenia; LIHC cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.84 0.35 3.73e-11 Bipolar disorder; LIHC cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.97 11.93 0.54 1.12e-27 Alzheimer's disease; LIHC cis rs5769765 1.000 rs738711 chr22:50282603 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.2 0.45 3.71e-18 Schizophrenia; LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg05896524 chr21:47604654 C21orf56 0.48 7.33 0.37 1.63e-12 Testicular germ cell tumor; LIHC cis rs1046896 1.000 rs1046896 chr17:80685533 A/G cg02398342 chr17:80708632 TBCD;FN3K -0.46 -7.03 -0.36 1.15e-11 Glycated hemoglobin levels; LIHC cis rs9296092 0.538 rs9469488 chr6:33517117 G/T cg13560919 chr6:33536144 NA -0.39 -6.29 -0.32 9.47e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs10050311 0.790 rs72667716 chr4:87833928 G/A cg04118154 chr1:45140072 C1orf228;TMEM53 -0.48 -6.18 -0.32 1.81e-9 Insulin-related traits; LIHC cis rs9326248 0.953 rs634960 chr11:117072963 T/C cg01368799 chr11:117014884 PAFAH1B2 -0.41 -5.81 -0.3 1.46e-8 Blood protein levels; LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg14893161 chr1:205819251 PM20D1 0.67 9.98 0.47 9.49e-21 Menarche (age at onset); LIHC trans rs9951602 0.512 rs1599636 chr18:76643916 G/A cg02800362 chr5:177631904 HNRNPAB 0.64 10.24 0.48 1.24e-21 Obesity-related traits; LIHC cis rs16866061 1.000 rs34345163 chr2:225459080 A/G cg12698349 chr2:225449008 CUL3 0.79 13.79 0.6 1e-34 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs4927850 0.918 rs4361313 chr3:195752260 A/G cg16724585 chr3:197361211 NA -0.46 -6.4 -0.33 5.25e-10 Pancreatic cancer; LIHC cis rs2070488 1.000 rs7373816 chr3:38490443 C/A cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC cis rs7903847 0.642 rs2275090 chr10:99148151 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg23758822 chr17:41437982 NA 0.94 17.64 0.69 5.76e-50 Menopause (age at onset); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg26079571 chr12:3186499 TSPAN9 -0.45 -6.13 -0.31 2.48e-9 Bilirubin levels; LIHC cis rs12887734 0.524 rs4906363 chr14:104210239 G/A cg01849466 chr14:104193079 ZFYVE21 -0.4 -6.11 -0.31 2.71e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs738322 0.934 rs84473 chr22:38557326 T/C cg17652424 chr22:38574118 PLA2G6 -0.2 -6.03 -0.31 4.22e-9 Cutaneous nevi; LIHC cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg16049864 chr8:95962084 TP53INP1 -0.63 -11.88 -0.54 1.78e-27 Type 2 diabetes; LIHC cis rs826838 1.000 rs4768328 chr12:39129315 C/T cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs7944735 0.508 rs2138767 chr11:47629793 T/C cg20307385 chr11:47447363 PSMC3 -0.52 -5.99 -0.31 5.38e-9 Intraocular pressure; LIHC cis rs3027234 0.734 rs11650309 chr17:8129538 C/G cg06726167 chr17:8076949 TMEM107 -0.54 -6.08 -0.31 3.28e-9 Telomere length; LIHC cis rs9303280 0.806 rs12936409 chr17:38043649 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.16 0.36 5.04e-12 Self-reported allergy; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09901100 chr7:134867116 NA 0.41 6.07 0.31 3.34e-9 Longevity; LIHC cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg20607798 chr8:58055168 NA 0.62 7.76 0.39 9.81e-14 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 11.66 0.53 1.11e-26 Alzheimer's disease; LIHC trans rs1459104 0.636 rs559362 chr11:55275456 T/G cg03929089 chr4:120376271 NA 0.62 6.35 0.32 6.82e-10 Body mass index; LIHC cis rs4759375 0.790 rs28820735 chr12:123878507 C/T cg00376283 chr12:123451042 ABCB9 0.49 6.31 0.32 8.6e-10 HDL cholesterol; LIHC cis rs7091068 0.518 rs4919436 chr10:95461475 C/T cg20715218 chr10:95462985 C10orf4 0.59 8.52 0.42 5.08e-16 Urinary tract infection frequency; LIHC cis rs5769707 0.933 rs2157444 chr22:49994292 A/G cg01652190 chr22:50026171 C22orf34 -0.3 -6.78 -0.34 5.31e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs739401 0.527 rs423236 chr11:3065916 C/T cg05729581 chr11:3078854 CARS -0.43 -5.86 -0.3 1.1e-8 Longevity; LIHC cis rs2404602 0.684 rs2047504 chr15:76883516 A/T cg23625390 chr15:77176239 SCAPER -0.53 -8.71 -0.43 1.32e-16 Blood metabolite levels; LIHC cis rs7607659 1 rs7607659 chr2:105267490 C/T cg12236088 chr2:105275812 NA -0.53 -6.32 -0.32 8.34e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7707921 0.541 rs10066167 chr5:81495445 C/T cg15871215 chr5:81402204 ATG10 0.6 8.03 0.4 1.61e-14 Breast cancer; LIHC cis rs116095464 0.558 rs12173244 chr5:269524 G/A cg22857025 chr5:266934 NA -1.51 -18.32 -0.7 1.05e-52 Breast cancer; LIHC cis rs9811920 0.609 rs704583 chr3:99643693 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs7534824 0.543 rs60978318 chr1:101400413 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.74 0.39 1.15e-13 Refractive astigmatism; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.86e-9 Total body bone mineral density; LIHC cis rs9381040 0.610 rs2235678 chr6:41020510 G/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.2 -0.32 1.66e-9 Alzheimer's disease (late onset); LIHC cis rs1152591 0.967 rs1152589 chr14:64683926 A/T cg23250157 chr14:64679961 SYNE2 -0.46 -6.72 -0.34 7.84e-11 Atrial fibrillation; LIHC cis rs67981189 0.679 rs221901 chr14:71602226 C/T cg15816911 chr14:71606274 NA -0.4 -6.41 -0.33 4.72e-10 Schizophrenia; LIHC cis rs3784262 0.631 rs4646584 chr15:58305402 C/T cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.73 -0.3 2.21e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6430585 0.941 rs7589832 chr2:136504101 A/C cg07169764 chr2:136633963 MCM6 1.03 14.16 0.61 3.84e-36 Corneal structure; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg10755058 chr3:40428713 ENTPD3 -0.39 -6.93 -0.35 2.11e-11 Renal cell carcinoma; LIHC cis rs9733 0.715 rs12402006 chr1:150869829 G/A cg13175981 chr1:150552382 MCL1 0.48 6.82 0.35 4.16e-11 Tonsillectomy; LIHC cis rs10838687 0.800 rs7124958 chr11:47347260 C/T cg26139080 chr11:47293733 MADD -0.42 -5.82 -0.3 1.39e-8 Proinsulin levels; LIHC cis rs2286885 1.000 rs7851961 chr9:129249140 G/A cg15282417 chr9:129245246 FAM125B 0.41 6.58 0.34 1.75e-10 Intraocular pressure; LIHC cis rs7116495 1.000 rs28504107 chr11:71832519 G/A cg26138937 chr11:71823887 C11orf51 0.73 7.41 0.37 9.67e-13 Severe influenza A (H1N1) infection; LIHC cis rs739401 0.967 rs451041 chr11:3060725 C/T cg25174290 chr11:3078921 CARS 0.43 6.58 0.34 1.74e-10 Longevity; LIHC cis rs6582630 0.555 rs10748382 chr12:38504529 C/T cg13010199 chr12:38710504 ALG10B 0.44 5.99 0.31 5.45e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs4650994 0.571 rs35758545 chr1:178511924 C/T cg05350800 chr1:178550844 NA -0.33 -7.11 -0.36 6.87e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10792665 0.844 rs7930200 chr11:82649880 T/C cg24227371 chr11:82718527 RAB30 -0.31 -7.47 -0.37 6.66e-13 Obesity-related traits; LIHC cis rs853679 0.517 rs9348793 chr6:28084189 G/A cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg11644478 chr21:40555479 PSMG1 0.77 9.24 0.45 2.7e-18 Cognitive function; LIHC trans rs6598955 0.572 rs12089219 chr1:26638751 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.75 -7.85 -0.39 5.31e-14 Obesity-related traits; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg24693881 chr1:107596107 NA -0.55 -9.66 -0.46 1.13e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg12386194 chr3:101231763 SENP7 -0.44 -6.47 -0.33 3.47e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg02931644 chr1:25747376 RHCE 0.34 7.4 0.37 1.09e-12 Plateletcrit;Mean corpuscular volume; LIHC cis rs6582630 0.502 rs1589390 chr12:38416139 C/T cg26384229 chr12:38710491 ALG10B -0.47 -6.13 -0.31 2.46e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs908922 0.676 rs1001834 chr1:152495940 C/A cg23254163 chr1:152506842 NA 0.23 5.91 0.3 8.5e-9 Hair morphology; LIHC cis rs62103177 0.683 rs62101232 chr18:77722454 T/C cg20368463 chr18:77673604 PQLC1 0.5 5.76 0.3 1.89e-8 Opioid sensitivity; LIHC cis rs4819052 0.851 rs4819041 chr21:46659955 C/T cg22633049 chr21:46681294 NA -0.34 -5.99 -0.31 5.42e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11105298 0.891 rs6538190 chr12:89885942 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.52 -0.38 4.86e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10193935 0.792 rs6735571 chr2:42491951 C/T cg27598129 chr2:42591480 NA -0.69 -10.5 -0.49 1.54e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs4638749 0.677 rs12712017 chr2:108843556 C/T cg25838818 chr2:108905173 SULT1C2 -0.4 -7.03 -0.36 1.15e-11 Blood pressure; LIHC cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg07424592 chr7:64974309 NA 0.73 8.54 0.42 4.46e-16 Diabetic kidney disease; LIHC cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs6545977 0.531 rs2539982 chr2:63111004 G/A cg17519650 chr2:63277830 OTX1 0.55 9.3 0.45 1.68e-18 Prostate cancer; LIHC cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs10463316 0.817 rs6895187 chr5:150775909 G/A cg03212797 chr5:150827313 SLC36A1 -0.44 -6.66 -0.34 1.13e-10 Metabolite levels (Pyroglutamine); LIHC cis rs4689642 0.709 rs4689090 chr4:7226751 G/T cg21353189 chr4:7228343 SORCS2 0.36 6.1 0.31 2.9e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.07e-10 Bipolar disorder; LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs3736485 0.934 rs2414106 chr15:51868741 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1.05e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6831352 0.879 rs29001196 chr4:100054116 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs539096 0.540 rs37452 chr1:44297573 A/C cg12908607 chr1:44402522 ARTN -0.47 -7.95 -0.4 2.69e-14 Intelligence (multi-trait analysis); LIHC cis rs6809651 0.524 rs1356292 chr3:185824903 C/T cg00760338 chr3:185826511 ETV5 0.89 13.38 0.59 3.89e-33 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs4819052 0.851 rs28442024 chr21:46674475 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 11.04 0.51 1.89e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9309711 0.621 rs12993215 chr2:3473727 T/C cg10845886 chr2:3471009 TTC15 -0.45 -8.12 -0.4 8.53e-15 Neurofibrillary tangles; LIHC cis rs12824058 0.831 rs7299065 chr12:130809661 A/T cg24229701 chr12:130821962 PIWIL1 0.44 6.78 0.34 5.4e-11 Menopause (age at onset); LIHC cis rs12477438 0.748 rs7558239 chr2:99640581 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.41 -0.53 8.75e-26 Chronic sinus infection; LIHC cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg04944784 chr2:26401820 FAM59B 0.72 9.19 0.45 3.85e-18 Gut microbiome composition (summer); LIHC cis rs600806 0.850 rs10858091 chr1:109935578 T/C cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs939574 0.790 rs72955444 chr2:220094673 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.87 6.36 0.33 6.41e-10 Platelet distribution width; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09002469 chr12:123459295 OGFOD2;ABCB9 0.45 6.36 0.33 6.58e-10 Pancreatic cancer; LIHC cis rs2832191 0.692 rs8134627 chr21:30349069 C/T cg24692254 chr21:30365293 RNF160 -0.85 -15.13 -0.63 5.9e-40 Dental caries; LIHC cis rs1712517 0.771 rs2292807 chr10:105155645 T/C cg05636881 chr10:105038444 INA 0.48 7.4 0.37 1.07e-12 Migraine; LIHC cis rs13004237 1 rs13004237 chr2:172833139 A/G cg13550731 chr2:172543902 DYNC1I2 -0.44 -7.3 -0.37 2.05e-12 Schizophrenia; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.48 -6.79 -0.34 5.01e-11 Lymphocyte counts; LIHC cis rs4808199 0.847 rs34647936 chr19:19548239 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.42 5.92 0.3 7.9e-9 Nonalcoholic fatty liver disease; LIHC trans rs61931739 0.500 rs6488211 chr12:34375620 A/T cg26384229 chr12:38710491 ALG10B -0.6 -7.57 -0.38 3.46e-13 Morning vs. evening chronotype; LIHC cis rs910316 0.763 rs175435 chr14:75612025 A/G cg11812906 chr14:75593930 NEK9 0.71 13.22 0.58 1.7e-32 Height; LIHC cis rs3768617 0.510 rs12095664 chr1:183101686 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC trans rs801193 0.967 rs2420827 chr7:66147101 G/A cg26939375 chr7:64535504 NA -0.39 -6.14 -0.32 2.25e-9 Aortic root size; LIHC cis rs17685 0.725 rs2302436 chr7:75676988 A/T cg04592579 chr7:75616294 TMEM120A -0.39 -6.68 -0.34 9.71e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs921968 0.591 rs6717107 chr2:219588697 A/G cg02985541 chr2:219472218 PLCD4 -0.38 -6.66 -0.34 1.07e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs4629710 0.592 rs4424112 chr6:131563788 C/T cg12606694 chr6:131520996 AKAP7 0.64 7.4 0.37 1.07e-12 Multiple myeloma (IgH translocation); LIHC cis rs8180040 0.932 rs62246474 chr3:47398130 C/T cg27129171 chr3:47204927 SETD2 -0.64 -10.96 -0.51 3.59e-24 Colorectal cancer; LIHC cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg06238570 chr21:40685208 BRWD1 0.58 6.99 0.35 1.48e-11 Cognitive function; LIHC cis rs2012796 0.785 rs61986593 chr14:81840659 G/A cg23690444 chr14:81902736 NA -0.49 -6.8 -0.35 4.74e-11 Night sleep phenotypes; LIHC cis rs3540 0.576 rs10152871 chr15:91047469 G/A cg22089800 chr15:90895588 ZNF774 -0.59 -8.15 -0.4 6.93e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs4474465 0.790 rs6592785 chr11:78235095 C/T cg27205649 chr11:78285834 NARS2 0.39 5.91 0.3 8.1e-9 Alzheimer's disease (survival time); LIHC cis rs876084 0.505 rs4431629 chr8:121108668 C/T cg06265175 chr8:121136014 COL14A1 0.48 7.83 0.39 6.23e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1728785 0.901 rs698715 chr16:68560896 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.08 0.31 3.27e-9 Ulcerative colitis; LIHC cis rs1552244 0.554 rs2272119 chr3:10049352 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.73 0.39 1.18e-13 Alzheimer's disease; LIHC cis rs7103648 1.000 rs10838705 chr11:47424931 G/A cg20307385 chr11:47447363 PSMC3 1.03 18.23 0.7 2.34e-52 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs35306767 0.951 rs55742421 chr10:961037 A/C cg20503657 chr10:835505 NA 1.09 11.36 0.52 1.33e-25 Eosinophil percentage of granulocytes; LIHC cis rs7223966 1.000 rs8069687 chr17:61883023 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.54 -6.48 -0.33 3.19e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2425143 1.000 rs55761608 chr20:34344226 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -6.92 -0.35 2.29e-11 Blood protein levels; LIHC cis rs7412746 0.611 rs3768018 chr1:150723747 T/C cg15448220 chr1:150897856 SETDB1 0.41 6.28 0.32 1.01e-9 Melanoma; LIHC cis rs7633770 0.643 rs59048074 chr3:46689155 C/T cg11219411 chr3:46661640 NA -0.36 -5.95 -0.31 6.55e-9 Coronary artery disease; LIHC cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs72627123 0.867 rs57482759 chr14:74485523 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.68 0.46 9.74e-20 Morning vs. evening chronotype; LIHC cis rs2832077 0.527 rs2250141 chr21:30241984 A/T cg03476357 chr21:30257390 N6AMT1 0.53 7.74 0.39 1.15e-13 Cognitive test performance; LIHC cis rs17685 0.753 rs1104878 chr7:75685593 G/T cg04610667 chr7:75704037 NA -0.35 -6.25 -0.32 1.23e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6088580 0.634 rs6059850 chr20:33044784 C/G cg08999081 chr20:33150536 PIGU 0.67 13.33 0.58 6.18e-33 Glomerular filtration rate (creatinine); LIHC cis rs17685 0.753 rs6976532 chr7:75681094 A/G cg16684958 chr7:75615977 POR 0.5 8.56 0.42 3.99e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs881375 0.654 rs10760126 chr9:123662618 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.37 0.33 5.96e-10 Rheumatoid arthritis; LIHC cis rs992157 0.735 rs13430006 chr2:219113089 A/C cg20019365 chr2:219134978 PNKD;AAMP -0.8 -13.23 -0.58 1.52e-32 Colorectal cancer; LIHC cis rs67311347 1.000 rs9842564 chr3:40405810 A/G cg13409248 chr3:40428643 ENTPD3 -0.37 -6.06 -0.31 3.65e-9 Renal cell carcinoma; LIHC cis rs7937682 0.889 rs521155 chr11:111492563 G/A cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC trans rs7618501 1.000 rs2271961 chr3:49878113 C/T cg21582582 chr3:182698605 DCUN1D1 -0.53 -7.08 -0.36 8.26e-12 Intelligence (multi-trait analysis); LIHC cis rs714027 0.511 rs131274 chr22:30153864 G/A cg01021169 chr22:30184971 ASCC2 -0.31 -5.72 -0.3 2.34e-8 Lymphocyte counts; LIHC cis rs34375054 0.526 rs7302475 chr12:125677886 T/C cg25124228 chr12:125621409 AACS -0.45 -7.94 -0.39 2.94e-14 Post bronchodilator FEV1/FVC ratio; LIHC cis rs244293 0.965 rs244346 chr17:53196383 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.5 -0.38 5.39e-13 Menarche (age at onset); LIHC cis rs7772486 0.754 rs6932863 chr6:146021255 A/T cg23711669 chr6:146136114 FBXO30 -0.74 -13.62 -0.59 4.7e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.642 rs11189179 chr10:99143320 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg06481639 chr22:41940642 POLR3H -0.71 -7.08 -0.36 8.3e-12 Vitiligo; LIHC cis rs3806843 1.000 rs2240692 chr5:140183585 A/G cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs6516091 0.850 rs75701968 chr20:6049985 C/T cg25325723 chr20:6104886 FERMT1 -0.71 -5.88 -0.3 9.8e-9 Abdominal aortic aneurysm; LIHC cis rs250677 0.687 rs41181 chr5:148444257 C/G cg12140854 chr5:148520817 ABLIM3 0.45 6.22 0.32 1.47e-9 Breast cancer; LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg12016809 chr21:47604291 C21orf56 0.49 7.65 0.38 2.01e-13 Testicular germ cell tumor; LIHC cis rs60871478 0.578 rs62432900 chr7:826794 G/C cg04727924 chr7:799746 HEATR2 -0.59 -8.06 -0.4 1.3e-14 Cerebrospinal P-tau181p levels; LIHC cis rs10056811 0.556 rs55810502 chr5:74380959 A/G cg02573091 chr5:74908125 NA 0.5 6.27 0.32 1.07e-9 Coronary artery disease; LIHC trans rs6598955 0.671 rs12088858 chr1:26643708 C/A cg07461501 chr17:79650226 HGS;ARL16 -0.71 -7.22 -0.36 3.46e-12 Obesity-related traits; LIHC cis rs950776 0.616 rs647041 chr15:78880481 T/C cg06917634 chr15:78832804 PSMA4 -0.66 -8.9 -0.43 3.31e-17 Sudden cardiac arrest; LIHC trans rs1347297 0.789 rs7589565 chr2:179282337 A/G cg14011486 chr1:26737247 LIN28 0.45 7.09 0.36 7.87e-12 Alzheimer disease and age of onset; LIHC cis rs2380220 1.000 rs2380222 chr6:95975395 C/T cg04719120 chr6:96025338 MANEA 0.64 6.8 0.35 4.64e-11 Behavioural disinhibition (generation interaction); LIHC cis rs9902453 0.934 rs7223645 chr17:28491029 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.32 0.45 1.47e-18 Coffee consumption (cups per day); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23097686 chr12:98910128 TMPO;LOC100128191 -0.42 -6.05 -0.31 3.76e-9 Cognitive function; LIHC cis rs4243830 0.737 rs4908909 chr1:6599041 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.84 -9.45 -0.46 5.47e-19 Body mass index; LIHC cis rs425277 0.606 rs2257684 chr1:2077872 A/G cg03732007 chr1:2071316 PRKCZ 0.35 6.09 0.31 3.09e-9 Height; LIHC cis rs9818758 0.607 rs55873331 chr3:49597055 C/T cg07636037 chr3:49044803 WDR6 -0.66 -6.17 -0.32 1.95e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs3181245 0.641 rs3756821 chr6:24646821 C/T cg16906346 chr6:24646782 KIAA0319 -0.55 -7.65 -0.38 2.06e-13 Colorectal or endometrial cancer; LIHC cis rs748404 0.631 rs11070399 chr15:43646347 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.88 0.43 3.84e-17 Lung cancer; LIHC cis rs6088580 0.634 rs6059887 chr20:33101102 C/G cg08999081 chr20:33150536 PIGU 0.67 13.46 0.59 1.89e-33 Glomerular filtration rate (creatinine); LIHC cis rs986417 0.901 rs1955697 chr14:61028435 T/C cg27398547 chr14:60952738 C14orf39 0.69 7.55 0.38 4.08e-13 Gut microbiota (bacterial taxa); LIHC cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.52 -0.56 7.01e-30 Alzheimer's disease; LIHC cis rs9911578 0.935 rs7218105 chr17:57041119 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.52e-50 Intelligence (multi-trait analysis); LIHC cis rs4908760 0.669 rs4908506 chr1:8728978 A/C cg20416874 chr1:8611966 RERE -0.62 -11.78 -0.54 4.18e-27 Vitiligo; LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg00091569 chr3:40428383 ENTPD3 0.39 6.54 0.33 2.25e-10 Renal cell carcinoma; LIHC cis rs9393692 0.846 rs7771202 chr6:26279907 A/G cg00631329 chr6:26305371 NA -0.42 -7.18 -0.36 4.3e-12 Educational attainment; LIHC cis rs1863824 0.595 rs61859067 chr10:88159997 G/A cg07322936 chr10:88137208 NA -0.46 -5.92 -0.31 7.63e-9 Schizophrenia; LIHC cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs798554 0.686 rs7777484 chr7:2814271 A/G cg19717773 chr7:2847554 GNA12 -0.41 -7.36 -0.37 1.37e-12 Height; LIHC cis rs8060686 0.668 rs255056 chr16:68016185 G/C cg05110241 chr16:68378359 PRMT7 -0.52 -5.76 -0.3 1.87e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC cis rs16854884 0.632 rs35716467 chr3:143684993 C/A cg06585982 chr3:143692056 C3orf58 0.64 9.05 0.44 1.11e-17 Economic and political preferences (feminism/equality); LIHC cis rs561341 1.000 rs7216102 chr17:30259450 A/G cg12193833 chr17:30244370 NA -0.51 -5.75 -0.3 1.94e-8 Hip circumference adjusted for BMI; LIHC cis rs332507 0.601 rs7653534 chr3:124358041 T/C cg05980111 chr3:124395277 KALRN 0.31 6.04 0.31 4.04e-9 Plateletcrit; LIHC cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg10295955 chr4:187884368 NA -0.96 -22.31 -0.77 1.07e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs7312933 1.000 rs3229 chr12:42475888 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.84 0.35 3.63e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs35883536 0.588 rs72977389 chr1:101107053 A/C cg14515779 chr1:101123966 NA -0.59 -11.25 -0.52 3.52e-25 Monocyte count; LIHC cis rs2991971 0.934 rs2991974 chr1:46020654 A/G cg15605315 chr1:45957053 TESK2 0.45 5.97 0.31 5.81e-9 High light scatter reticulocyte count; LIHC cis rs7208859 0.623 rs11650973 chr17:29214045 G/A cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1577917 1.000 rs13217384 chr6:86720000 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.41 -0.37 9.78e-13 Response to antipsychotic treatment; LIHC cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg12292205 chr6:26970375 C6orf41 0.46 7.72 0.39 1.26e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs7615952 0.611 rs35321002 chr3:125612065 G/C cg05084668 chr3:125655381 ALG1L -0.8 -10.87 -0.51 8.03e-24 Blood pressure (smoking interaction); LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg25897951 chr4:1244024 CTBP1;C4orf42 -0.39 -5.72 -0.3 2.38e-8 Longevity; LIHC cis rs9911578 0.934 rs58092632 chr17:57111101 T/C cg12560992 chr17:57184187 TRIM37 -0.98 -17.84 -0.69 8.33e-51 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.866 rs6824111 chr4:120285968 T/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs1400745 0.812 rs72678789 chr14:35348201 T/G cg16230307 chr14:35515116 FAM177A1 -0.38 -6.02 -0.31 4.38e-9 Monocyte count; LIHC cis rs1538970 0.781 rs34768551 chr1:46020408 G/A cg24296786 chr1:45957014 TESK2 -0.48 -6.23 -0.32 1.35e-9 Platelet count; LIHC cis rs4718428 1.000 rs1830070 chr7:66349671 T/C cg18252515 chr7:66147081 NA -0.46 -6.04 -0.31 4.01e-9 Corneal structure; LIHC cis rs7103648 0.966 rs1534576 chr11:47419663 A/C cg20307385 chr11:47447363 PSMC3 -1.0 -17.34 -0.68 9.29e-49 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg02475777 chr4:1388615 CRIPAK -0.48 -7.06 -0.36 9.3e-12 Obesity-related traits; LIHC cis rs9640161 0.663 rs1916932 chr7:150021644 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.89 -0.43 3.45e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs1419980 0.730 rs11054939 chr12:7782439 C/G cg10578777 chr12:7781093 NA -0.4 -5.86 -0.3 1.1e-8 HDL cholesterol levels; LIHC cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.76e-11 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs858239 0.539 rs4504540 chr7:23186198 C/G cg23682824 chr7:23144976 KLHL7 0.43 6.51 0.33 2.64e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.12 0.4 8.3e-15 Height; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.6 8.61 0.42 2.67e-16 Lymphocyte counts; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03424826 chr18:59561551 RNF152 0.47 6.51 0.33 2.67e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.817 rs1390676 chr11:50056778 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.11 -0.78 7.6e-72 Height; LIHC cis rs11758351 1.000 rs79264785 chr6:26194121 C/T cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs11588062 0.601 rs4660344 chr1:46805222 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.48 7.4 0.37 1.06e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2412488 0.893 rs7682199 chr4:54343363 A/G cg22241045 chr4:54363911 LNX1 -0.42 -6.78 -0.34 5.19e-11 DNA methylation (variation); LIHC cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg18252515 chr7:66147081 NA -1.28 -17.19 -0.68 3.6e-48 Diabetic kidney disease; LIHC cis rs916888 0.610 rs142167 chr17:44795234 C/T cg01570182 chr17:44337453 NA -0.41 -5.75 -0.3 1.93e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9355610 0.727 rs2247315 chr6:167370211 A/C cg12798992 chr6:167411361 FGFR1OP -0.47 -7.37 -0.37 1.26e-12 Graves' disease; LIHC cis rs9393692 0.905 rs9393694 chr6:26279296 T/C cg13736514 chr6:26305472 NA -0.37 -6.23 -0.32 1.34e-9 Educational attainment; LIHC cis rs7312933 0.703 rs10492388 chr12:42608001 T/C cg17420585 chr12:42539391 GXYLT1 -0.38 -6.15 -0.32 2.22e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7659604 0.521 rs9993206 chr4:122686957 A/G cg19671926 chr4:122722719 EXOSC9 0.53 8.02 0.4 1.64e-14 Type 2 diabetes; LIHC cis rs61677309 1.000 rs67774926 chr11:118157623 C/G cg06090739 chr11:118230722 UBE4A 0.35 6.6 0.34 1.53e-10 Lung cancer in ever smokers; LIHC trans rs10411161 0.702 rs8110546 chr19:52383556 C/A cg22319618 chr22:45562946 NUP50 -0.6 -8.08 -0.4 1.13e-14 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01435196 chr19:46009946 VASP 0.5 6.79 0.34 4.94e-11 Lung function (FEV1/FVC); LIHC cis rs74544699 1.000 rs116254820 chr4:74804444 G/A cg02530824 chr4:74847766 PF4 0.62 6.4 0.33 5.22e-10 Growth-regulated protein alpha levels; LIHC trans rs2243480 0.901 rs2900904 chr7:65204264 C/G cg10756647 chr7:56101905 PSPH 1.11 13.62 0.59 4.91e-34 Diabetic kidney disease; LIHC cis rs507080 0.733 rs544452 chr11:118571357 G/T cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs1008375 1.000 rs4698199 chr4:17656738 G/C cg04450456 chr4:17643702 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2997447 0.655 rs12094933 chr1:26374779 T/C cg19633962 chr1:26362018 EXTL1 -0.62 -7.39 -0.37 1.11e-12 QRS complex (12-leadsum); LIHC trans rs6598955 0.671 rs7551557 chr1:26596614 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.76 -8.53 -0.42 4.81e-16 Obesity-related traits; LIHC cis rs644799 0.710 rs11021309 chr11:95501898 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.25 0.58 1.22e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12594515 1.000 rs12911309 chr15:45985719 G/C cg01629716 chr15:45996671 NA 0.52 9.56 0.46 2.41e-19 Waist circumference;Weight; LIHC cis rs5769765 0.778 rs4574208 chr22:50256738 C/T cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs9649465 0.561 rs688242 chr7:123420442 C/A cg03229431 chr7:123269106 ASB15 0.43 9.16 0.44 4.77e-18 Migraine; LIHC cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg08645402 chr16:4508243 NA 0.39 7.45 0.37 7.9e-13 Schizophrenia; LIHC cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.08 0.31 3.29e-9 Menopause (age at onset); LIHC trans rs61931739 0.500 rs11053260 chr12:34530215 T/G cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs7613875 0.521 rs4688754 chr3:50074641 G/T cg24110177 chr3:50126178 RBM5 0.56 9.12 0.44 6.64e-18 Body mass index; LIHC cis rs11122272 0.735 rs2749706 chr1:231527170 C/A cg06096015 chr1:231504339 EGLN1 0.5 9.28 0.45 2.01e-18 Hemoglobin concentration; LIHC cis rs1348850 0.574 rs13431105 chr2:178434674 A/G cg27490568 chr2:178487706 NA 1.08 12.3 0.55 4.95e-29 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2066819 0.786 rs111580405 chr12:56739557 A/G cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs7613875 0.620 rs17657664 chr3:50032008 T/G cg24110177 chr3:50126178 RBM5 -0.53 -8.62 -0.42 2.59e-16 Body mass index; LIHC cis rs611744 0.810 rs672161 chr8:109164182 G/A cg18478394 chr8:109455254 TTC35 0.39 6.66 0.34 1.1e-10 Dupuytren's disease; LIHC cis rs12824058 0.549 rs4759453 chr12:130824565 C/G cg26677194 chr12:130822605 PIWIL1 0.51 7.19 0.36 4.09e-12 Menopause (age at onset); LIHC cis rs6912958 0.712 rs4587138 chr6:88356915 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.88 -0.39 4.49e-14 Monocyte percentage of white cells; LIHC trans rs1814175 0.817 rs12277258 chr11:49940216 T/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs763121 0.853 rs5757231 chr22:39071658 C/T cg14440974 chr22:39074834 NA 0.44 7.07 0.36 8.66e-12 Menopause (age at onset); LIHC cis rs2075371 0.897 rs10488428 chr7:133997560 C/T cg11752832 chr7:134001865 SLC35B4 0.48 6.04 0.31 3.93e-9 Mean platelet volume; LIHC cis rs77633900 0.614 rs280024 chr15:77034518 A/C cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Non-glioblastoma glioma;Glioma; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08677755 chr19:7604888 PNPLA6 -0.42 -6.6 -0.34 1.58e-10 Calcium levels; LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg07002622 chr6:118822466 C6orf204;BRD7P3 0.56 5.92 0.3 7.98e-9 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09910967 chr6:139456200 HECA -0.44 -6.3 -0.32 9.27e-10 Pancreatic cancer; LIHC cis rs2576037 0.526 rs649076 chr18:44414614 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.57 0.5 9e-23 Personality dimensions; LIHC cis rs9534288 0.797 rs6561281 chr13:46596601 C/T cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs116248771 0.739 rs73156495 chr3:158420547 C/T cg16708174 chr3:158430962 RARRES1 0.46 6.31 0.32 8.56e-10 diarrhoeal disease at age 2; LIHC cis rs6964587 1.000 rs7806157 chr7:91601930 A/G cg17063962 chr7:91808500 NA 1.01 19.24 0.72 2.01e-56 Breast cancer; LIHC cis rs1707322 0.963 rs9787412 chr1:46371596 C/T cg06784218 chr1:46089804 CCDC17 0.34 6.09 0.31 3.11e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10744422 1.000 rs937766 chr12:123331094 G/T cg22842854 chr12:123319900 HIP1R -0.74 -9.76 -0.47 5.03e-20 Schizophrenia; LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg12379764 chr21:47803548 PCNT -0.54 -7.99 -0.4 2.08e-14 Testicular germ cell tumor; LIHC cis rs600806 0.888 rs2228604 chr1:109884775 A/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.2 -0.32 1.61e-9 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.779 rs10857066 chr4:120286596 C/T cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs5015933 0.815 rs13294021 chr9:128068388 G/A cg14078157 chr9:128172775 NA -0.37 -6.0 -0.31 4.99e-9 Body mass index; LIHC cis rs1552244 0.515 rs67342818 chr3:10166406 G/A cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg06634786 chr22:41940651 POLR3H -0.76 -7.89 -0.39 4.16e-14 Vitiligo; LIHC cis rs826838 0.967 rs826858 chr12:39116731 A/G cg26384229 chr12:38710491 ALG10B -0.64 -9.33 -0.45 1.33e-18 Heart rate; LIHC cis rs34375054 0.526 rs117431213 chr12:125675271 C/G cg25124228 chr12:125621409 AACS -0.45 -7.87 -0.39 4.77e-14 Post bronchodilator FEV1/FVC ratio; LIHC cis rs921968 0.541 rs576901 chr2:219424364 A/G cg02176678 chr2:219576539 TTLL4 0.53 7.44 0.37 8.1e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg06634786 chr22:41940651 POLR3H -0.66 -7.4 -0.37 1.04e-12 Vitiligo; LIHC cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs2228479 0.850 rs11646766 chr16:89838578 A/T cg19635926 chr16:89946313 TCF25 0.5 6.45 0.33 3.88e-10 Skin colour saturation; LIHC cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg27297192 chr10:134578999 INPP5A -0.48 -6.77 -0.34 5.53e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs634534 0.622 rs1308733 chr11:65720841 T/C cg17712092 chr4:129076599 LARP1B -0.66 -9.94 -0.47 1.27e-20 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg13395646 chr4:1353034 KIAA1530 -0.41 -6.42 -0.33 4.6e-10 Obesity-related traits; LIHC cis rs7772486 0.790 rs2265917 chr6:146212285 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.84 0.3 1.21e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs12602486 0.744 rs12603404 chr17:42223914 G/A cg13607699 chr17:42295918 UBTF -0.72 -6.27 -0.32 1.12e-9 Glycated hemoglobin levels; LIHC cis rs867186 0.541 rs117391907 chr20:33338811 G/A cg08999081 chr20:33150536 PIGU 0.6 5.75 0.3 1.98e-8 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs12594515 1.000 rs56412446 chr15:45996424 A/G cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs6963495 0.556 rs711433 chr7:105153191 A/G cg19920283 chr7:105172520 RINT1 -0.48 -6.17 -0.32 1.97e-9 Bipolar disorder (body mass index interaction); LIHC cis rs992157 0.764 rs1870123 chr2:219187698 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.1 0.48 3.8e-21 Colorectal cancer; LIHC cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2289583 0.503 rs12050494 chr15:75260896 G/A cg15902774 chr15:75289873 SCAMP5 0.33 5.83 0.3 1.31e-8 Systemic lupus erythematosus; LIHC cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg25894440 chr7:65020034 NA -0.54 -6.27 -0.32 1.06e-9 Diabetic kidney disease; LIHC cis rs7726839 0.574 rs11134149 chr5:637277 A/G cg09021430 chr5:549028 NA -0.39 -8.15 -0.4 6.78e-15 Obesity-related traits; LIHC cis rs4589502 1.000 rs4589502 chr15:67155069 C/T cg09911534 chr15:67153556 NA -0.43 -5.75 -0.3 1.97e-8 Lung cancer (smoking interaction); LIHC cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg24675658 chr1:53192096 ZYG11B 0.62 9.97 0.47 1.05e-20 Monocyte count; LIHC cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg03517284 chr6:25882590 NA -0.5 -6.07 -0.31 3.43e-9 Intelligence (multi-trait analysis); LIHC cis rs2066819 1.000 rs744051 chr12:56667298 C/T cg26734620 chr12:56694298 CS -1.3 -11.32 -0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs11675119 0.517 rs12619851 chr2:3492747 T/C cg15506890 chr2:3487001 NA -0.49 -7.5 -0.38 5.38e-13 Neurofibrillary tangles; LIHC cis rs769267 0.930 rs4808959 chr19:19572108 T/G cg03709012 chr19:19516395 GATAD2A 1.03 18.55 0.71 1.22e-53 Tonsillectomy; LIHC cis rs11122272 0.701 rs2486725 chr1:231540288 G/C cg06096015 chr1:231504339 EGLN1 0.49 9.07 0.44 9.82e-18 Hemoglobin concentration; LIHC cis rs372883 0.600 rs2832298 chr21:30743863 C/G cg08807101 chr21:30365312 RNF160 0.51 6.09 0.31 3.03e-9 Pancreatic cancer; LIHC cis rs9534288 0.700 rs7331032 chr13:46609040 C/T cg15192986 chr13:46630673 CPB2 -0.56 -8.64 -0.42 2.16e-16 Blood protein levels; LIHC cis rs12579753 0.957 rs35001833 chr12:82188510 C/G cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC cis rs34172651 0.617 rs9922436 chr16:24704490 C/G cg04756594 chr16:24857601 SLC5A11 0.38 6.43 0.33 4.37e-10 Intelligence (multi-trait analysis); LIHC cis rs769267 0.930 rs2301786 chr19:19413947 A/G cg03709012 chr19:19516395 GATAD2A 0.93 15.59 0.64 9.01e-42 Tonsillectomy; LIHC cis rs2289328 0.943 rs3803360 chr15:40662669 C/T cg26241852 chr15:40650142 DISP2 -0.48 -6.1 -0.31 2.79e-9 Intelligence (multi-trait analysis);Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.58 8.92 0.43 2.89e-17 Height; LIHC cis rs67478160 0.643 rs11624184 chr14:104240998 A/G cg24130564 chr14:104152367 KLC1 -0.38 -6.05 -0.31 3.83e-9 Schizophrenia; LIHC cis rs40363 0.645 rs250630 chr16:3524242 C/T cg21433313 chr16:3507492 NAT15 0.46 7.77 0.39 9.13e-14 Tuberculosis; LIHC cis rs9304742 0.962 rs1044467 chr19:53452769 A/G cg01285391 chr19:53465759 ZNF816A -0.33 -5.85 -0.3 1.14e-8 Psoriasis; LIHC cis rs6430585 0.702 rs2304601 chr2:136528034 C/A cg07169764 chr2:136633963 MCM6 1.15 16.19 0.66 3.6e-44 Corneal structure; LIHC trans rs4906332 1.000 rs17617307 chr14:103904965 C/G cg17675199 chr6:35436792 RPL10A 0.33 6.52 0.33 2.57e-10 Coronary artery disease; LIHC cis rs11229555 1.000 rs11229545 chr11:58386650 A/G cg15696309 chr11:58395628 NA -0.73 -8.95 -0.44 2.24e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1023500 0.505 rs134886 chr22:42673856 C/T cg15557168 chr22:42548783 NA 0.35 6.04 0.31 3.96e-9 Schizophrenia; LIHC cis rs9814567 0.762 rs13071852 chr3:134223217 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 7.25 0.36 2.87e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12477438 0.520 rs10865029 chr2:99718298 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.68 0.78 3.75e-70 Chronic sinus infection; LIHC cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg18876405 chr7:65276391 NA -0.56 -9.58 -0.46 1.99e-19 Aortic root size; LIHC cis rs2204008 0.837 rs10876019 chr12:37985477 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.78 0.3 1.69e-8 Bladder cancer; LIHC cis rs6089584 0.526 rs6061965 chr20:60607858 A/C cg06108461 chr20:60628389 TAF4 -0.62 -8.6 -0.42 2.89e-16 Body mass index; LIHC cis rs2029362 0.513 rs10767667 chr11:27746549 C/T cg18117895 chr11:27722066 BDNF -0.39 -5.76 -0.3 1.87e-8 Total body bone mineral density; LIHC cis rs67311347 0.824 rs73073561 chr3:40357298 G/T cg09455208 chr3:40491958 NA 0.34 6.4 0.33 5.16e-10 Renal cell carcinoma; LIHC cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg11301795 chr4:187892539 NA -0.26 -6.83 -0.35 3.79e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.78 0.54 3.93e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4332037 0.722 rs4721140 chr7:1917635 A/T cg23043544 chr7:2124092 MAD1L1 -0.4 -5.99 -0.31 5.41e-9 Bipolar disorder; LIHC cis rs9470366 0.509 rs4714001 chr6:36638175 G/A cg00935119 chr6:36647544 CDKN1A 0.49 7.03 0.36 1.16e-11 QRS duration; LIHC cis rs2842992 0.672 rs4708845 chr6:160219601 T/G cg11366901 chr6:160182831 ACAT2 0.93 15.41 0.64 4.56e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs2404602 0.647 rs12440511 chr15:76993135 A/G cg23625390 chr15:77176239 SCAPER -0.54 -8.96 -0.44 2.12e-17 Blood metabolite levels; LIHC cis rs7762018 1.000 rs4716378 chr6:170086568 G/C cg13891659 chr6:170190454 C6orf122;C6orf208 0.53 6.19 0.32 1.75e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs1348850 0.958 rs10930799 chr2:178459325 G/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.74 10.73 0.5 2.39e-23 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.97 0.44 1.95e-17 Platelet count; LIHC cis rs6976053 0.518 rs314358 chr7:100410657 A/G cg08302003 chr7:100435192 NA -0.39 -6.32 -0.32 8.02e-10 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC cis rs2070488 1.000 rs13072809 chr3:38468171 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.92 0.65 4.3e-43 Electrocardiographic conduction measures; LIHC cis rs611744 0.967 rs688746 chr8:109225725 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs1878931 0.697 rs1044390 chr16:3432594 T/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.97 22.41 0.77 4.49e-69 Body mass index (adult); LIHC cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.56 7.83 0.39 6.24e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.64 0.38 2.16e-13 Prudent dietary pattern; LIHC cis rs7772486 0.754 rs864148 chr6:145976675 T/C cg23711669 chr6:146136114 FBXO30 -0.72 -12.94 -0.57 1.9e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs9348721 0.562 rs9393716 chr6:26376868 A/G cg09904177 chr6:26538194 HMGN4 -0.5 -5.89 -0.3 9.43e-9 Intelligence (multi-trait analysis); LIHC cis rs8084351 0.560 rs7506428 chr18:50557938 A/C cg24270629 chr18:50823537 DCC 0.39 5.85 0.3 1.12e-8 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs16877106 1.000 rs73252579 chr4:25316691 G/A cg04796973 chr4:25314218 ZCCHC4 0.61 5.77 0.3 1.75e-8 Weight; LIHC cis rs2425143 1.000 rs2425141 chr20:34350123 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -7.06 -0.36 9.17e-12 Blood protein levels; LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg03854865 chr6:26224070 HIST1H3E 0.63 7.23 0.36 3.28e-12 Gout;Renal underexcretion gout; LIHC cis rs16958440 0.867 rs3809965 chr18:44676872 G/A cg17192377 chr18:44677553 HDHD2 0.93 8.68 0.42 1.66e-16 Sitting height ratio; LIHC trans rs801193 0.636 rs10233806 chr7:66118248 G/C cg10756647 chr7:56101905 PSPH -0.47 -7.05 -0.36 1.01e-11 Aortic root size; LIHC cis rs72627123 0.656 rs76479281 chr14:74564609 C/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.86 8.36 0.41 1.65e-15 Morning vs. evening chronotype; LIHC cis rs999943 0.846 rs10947420 chr6:33611061 C/G cg14003231 chr6:33640908 ITPR3 0.35 7.47 0.37 6.59e-13 Obesity (extreme); LIHC cis rs9443189 0.901 rs2038624 chr6:76560707 T/C cg01950844 chr6:76311363 SENP6 -0.52 -6.76 -0.34 5.8200000000000003e-11 Prostate cancer; LIHC cis rs7613875 0.600 rs2856238 chr3:50158191 C/T cg21467203 chr3:49911342 NA -0.55 -10.06 -0.48 4.97e-21 Body mass index; LIHC cis rs3862260 0.509 rs12076924 chr1:120165826 C/T cg11530693 chr1:120165357 ZNF697 0.48 7.37 0.37 1.29e-12 Systemic lupus erythematosus; LIHC cis rs7937682 0.632 rs4935811 chr11:111679262 C/T cg09085632 chr11:111637200 PPP2R1B 0.94 13.85 0.6 6.18e-35 Primary sclerosing cholangitis; LIHC cis rs769267 0.930 rs4808959 chr19:19572108 T/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.16 0.32 2.01e-9 Tonsillectomy; LIHC cis rs9322817 1.000 rs6942231 chr6:105191814 C/T cg02098413 chr6:105308735 HACE1 -0.39 -6.39 -0.33 5.59e-10 Thyroid stimulating hormone; LIHC trans rs8002861 0.810 rs7334812 chr13:44445538 C/T cg17145862 chr1:211918768 LPGAT1 0.58 10.75 0.5 2.06e-23 Leprosy; LIHC cis rs694739 0.595 rs11542299 chr11:64138805 T/C cg02228329 chr11:64053129 BAD;GPR137 0.6 8.15 0.4 7.09e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21101222 chr5:151138161 ATOX1 -0.46 -7.14 -0.36 5.8e-12 Pancreatic cancer; LIHC trans rs10506458 0.915 rs79133015 chr12:63396838 G/A cg22491629 chr6:157744540 C6orf35 -0.61 -11.0 -0.51 2.6e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg08677398 chr8:58056175 NA 0.4 6.27 0.32 1.11e-9 Developmental language disorder (linguistic errors); LIHC cis rs561341 0.843 rs2028067 chr17:30239698 T/C cg13647721 chr17:30228624 UTP6 0.69 7.18 0.36 4.43e-12 Hip circumference adjusted for BMI; LIHC cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg14004847 chr7:1930337 MAD1L1 -0.64 -9.95 -0.47 1.22e-20 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.966 rs807932 chr3:47354241 C/T cg02527881 chr3:46936655 PTH1R -0.31 -6.03 -0.31 4.15e-9 Colorectal cancer; LIHC cis rs6933660 0.720 rs6936936 chr6:151753395 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.53 -8.1 -0.4 9.94e-15 Menarche (age at onset); LIHC cis rs61774743 0.636 rs1892423 chr1:41849340 A/C cg08462924 chr1:41848221 NA 0.35 5.94 0.31 6.83e-9 Intelligence (multi-trait analysis); LIHC cis rs2292096 1.000 rs2275193 chr1:200824108 C/T cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -6.07 -0.31 3.48e-9 Epilepsy; LIHC cis rs8067545 0.562 rs2526481 chr17:20127018 T/C cg13482628 chr17:19912719 NA -0.42 -6.94 -0.35 1.93e-11 Schizophrenia; LIHC cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg11766577 chr21:47581405 C21orf56 -0.44 -7.09 -0.36 7.74e-12 Testicular germ cell tumor; LIHC cis rs637571 0.522 rs649000 chr11:65742933 T/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.35 0.45 1.19e-18 Eosinophil percentage of white cells; LIHC cis rs7659604 0.539 rs2221628 chr4:122795361 G/A cg19748678 chr4:122722346 EXOSC9 0.68 11.29 0.52 2.51e-25 Type 2 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01813165 chr2:202646406 ALS2 0.4 6.33 0.32 7.71e-10 Cognitive function; LIHC cis rs3796352 0.881 rs35384050 chr3:53008769 G/T cg04865290 chr3:52927548 TMEM110 -0.51 -5.87 -0.3 1.02e-8 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7659604 0.539 rs11098645 chr4:122729251 G/A cg20573242 chr4:122745356 CCNA2 0.53 7.64 0.38 2.25e-13 Type 2 diabetes; LIHC cis rs7827545 0.644 rs7386524 chr8:135534005 T/C cg17885191 chr8:135476712 NA -0.38 -6.48 -0.33 3.11e-10 Hypertension (SNP x SNP interaction); LIHC cis rs61542988 0.570 rs7781074 chr7:22826360 A/G cg11367502 chr7:22862612 TOMM7 -0.54 -8.85 -0.43 4.71e-17 Fibrinogen levels; LIHC cis rs116095464 0.558 rs56043030 chr5:220917 A/G cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs3818285 0.655 rs2475277 chr10:111639730 C/T cg00817464 chr10:111662876 XPNPEP1 0.67 11.26 0.52 3.06e-25 Superior crus of antihelix expression; LIHC cis rs870825 0.616 rs9715644 chr4:185632965 C/T cg04058563 chr4:185651563 MLF1IP 0.7 7.36 0.37 1.36e-12 Blood protein levels; LIHC cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg10802521 chr3:52805072 NEK4 -0.38 -6.37 -0.33 5.95e-10 Electroencephalogram traits; LIHC cis rs262150 0.851 rs2730249 chr7:158767628 A/G cg19418458 chr7:158789849 NA 0.37 6.48 0.33 3.12e-10 Facial morphology (factor 20); LIHC cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg07092213 chr7:1199455 ZFAND2A 0.41 6.1 0.31 2.8e-9 Longevity;Endometriosis; LIHC cis rs1577917 0.917 rs2218594 chr6:86543766 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.1 -0.4 9.8e-15 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs6905242 chr6:8471799 A/C cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg14004847 chr7:1930337 MAD1L1 0.57 8.6 0.42 2.94e-16 Bipolar disorder and schizophrenia; LIHC cis rs9892942 1 rs9892942 chr17:27178761 C/T cg20469991 chr17:27169893 C17orf63 -0.56 -6.39 -0.33 5.45e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6430585 0.591 rs12477421 chr2:136433740 A/G cg07169764 chr2:136633963 MCM6 0.7 8.81 0.43 6.38e-17 Corneal structure; LIHC cis rs9549367 0.713 rs56002882 chr13:113830694 T/C cg00898013 chr13:113819073 PROZ -0.44 -7.39 -0.37 1.17e-12 Platelet distribution width; LIHC cis rs7116495 0.609 rs2511120 chr11:71786211 C/T cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.07e-17 Severe influenza A (H1N1) infection; LIHC trans rs2243480 1.000 rs313803 chr7:65514731 G/A cg10756647 chr7:56101905 PSPH 1.08 13.33 0.58 6.29e-33 Diabetic kidney disease; LIHC cis rs10911232 0.507 rs6668980 chr1:183018857 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.49 0.49 1.7e-22 Hypertriglyceridemia; LIHC cis rs6570726 0.935 rs442254 chr6:145849118 T/C cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs922107 0.738 rs12125224 chr1:90053563 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.69 -0.38 1.58e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs9399135 0.622 rs3817776 chr6:135256756 C/T cg24558204 chr6:135376177 HBS1L -0.36 -5.77 -0.3 1.75e-8 Red blood cell count; LIHC cis rs7520050 0.933 rs11211203 chr1:46315592 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2976388 0.669 rs2976391 chr8:143762724 C/A cg06565975 chr8:143823917 SLURP1 0.32 6.25 0.32 1.2e-9 Urinary tract infection frequency; LIHC cis rs4718428 0.705 rs62465692 chr7:66295745 T/C cg18252515 chr7:66147081 NA -0.68 -9.28 -0.45 1.97e-18 Corneal structure; LIHC cis rs8078723 0.866 rs3935280 chr17:38189055 A/G cg17467752 chr17:38218738 THRA -0.76 -14.45 -0.62 2.88e-37 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01947301 chr1:205718900 NUCKS1 -0.48 -7.03 -0.36 1.14e-11 Cognitive function; LIHC cis rs2075371 0.966 rs1646646 chr7:133996905 G/T cg20476274 chr7:133979776 SLC35B4 0.74 12.24 0.55 8.17e-29 Mean platelet volume; LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.19 0.55 1.27e-28 Height; LIHC cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg25894440 chr7:65020034 NA 0.58 6.75 0.34 6.47e-11 Diabetic kidney disease; LIHC cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.596 rs6692960 chr1:150695965 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg00091569 chr3:40428383 ENTPD3 0.38 6.46 0.33 3.66e-10 Renal cell carcinoma; LIHC cis rs12579753 0.879 rs12579544 chr12:82164043 A/C cg07988820 chr12:82153109 PPFIA2 -0.48 -6.17 -0.32 1.9e-9 Resting heart rate; LIHC cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg09222892 chr1:25734099 RHCE -0.46 -8.46 -0.42 8.02e-16 Erythrocyte sedimentation rate; LIHC cis rs798554 0.797 rs798488 chr7:2802522 T/C cg19717773 chr7:2847554 GNA12 -0.41 -6.65 -0.34 1.16e-10 Height; LIHC cis rs4665809 0.509 rs62128431 chr2:26398116 C/T cg04944784 chr2:26401820 FAM59B 0.7 7.54 0.38 4.23e-13 Gut microbiome composition (summer); LIHC cis rs7131987 0.903 rs10843371 chr12:29414232 G/A cg14222432 chr12:29376421 FAR2 0.37 7.11 0.36 6.68e-12 QT interval; LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg00280220 chr17:61926910 NA 0.42 6.84 0.35 3.58e-11 Prudent dietary pattern; LIHC cis rs1005277 0.579 rs2983343 chr10:38383332 A/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs8180040 0.676 rs7636252 chr3:47013542 T/G cg27129171 chr3:47204927 SETD2 0.61 10.6 0.5 6.81e-23 Colorectal cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03327327 chr1:214779620 CENPF -0.45 -6.68 -0.34 9.47e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg01238044 chr22:24384105 GSTT1 -0.44 -6.01 -0.31 4.89e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6960043 0.818 rs10267273 chr7:15053589 A/G cg19272540 chr7:15055459 NA -0.25 -6.84 -0.35 3.7e-11 Type 2 diabetes; LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.67 0.46 1.04e-19 Height; LIHC cis rs367615 0.537 rs1965670 chr5:108649798 A/T cg17395555 chr5:108820864 NA -0.28 -6.07 -0.31 3.46e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs11675119 0.517 rs12619851 chr2:3492747 T/C cg10845886 chr2:3471009 TTC15 -0.43 -7.68 -0.38 1.67e-13 Neurofibrillary tangles; LIHC cis rs7927592 0.956 rs11228277 chr11:68308324 G/A cg20283391 chr11:68216788 NA -0.53 -8.21 -0.41 4.64e-15 Total body bone mineral density; LIHC cis rs1577917 0.958 rs3857480 chr6:86535149 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.11 -0.4 8.96e-15 Response to antipsychotic treatment; LIHC cis rs6546537 0.955 rs35947226 chr2:69845829 C/G cg10773587 chr2:69614142 GFPT1 -0.43 -5.95 -0.31 6.75e-9 Serum thyroid-stimulating hormone levels; LIHC cis rs611744 0.647 rs11785776 chr8:109264933 C/T cg18478394 chr8:109455254 TTC35 0.42 7.24 0.36 3.07e-12 Dupuytren's disease; LIHC cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg11644478 chr21:40555479 PSMG1 0.77 9.67 0.46 9.97e-20 Cognitive function; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.4 0.81 1.03e-80 Prudent dietary pattern; LIHC cis rs6545883 0.929 rs3732170 chr2:61749716 C/T cg15711740 chr2:61764176 XPO1 -0.44 -6.19 -0.32 1.73e-9 Tuberculosis; LIHC cis rs12744310 0.836 rs12048808 chr1:41814308 G/C cg03962019 chr1:41807865 NA 0.4 5.92 0.31 7.69e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7762018 1.000 rs11961560 chr6:170130121 T/C cg13891659 chr6:170190454 C6orf122;C6orf208 0.54 6.33 0.32 7.48e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg13395646 chr4:1353034 KIAA1530 -0.63 -8.99 -0.44 1.66e-17 Obesity-related traits; LIHC cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg18357526 chr6:26021779 HIST1H4A 0.61 8.56 0.42 3.99e-16 Blood metabolite levels; LIHC cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg09025071 chr16:1593152 IFT140;TMEM204 0.32 6.32 0.32 8.11e-10 Coronary artery disease; LIHC cis rs12477438 0.798 rs7606635 chr2:99644782 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.56 -0.5 9.46e-23 Chronic sinus infection; LIHC trans rs8002861 0.935 rs9567299 chr13:44456969 G/A cg17145862 chr1:211918768 LPGAT1 0.67 13.07 0.58 6.1e-32 Leprosy; LIHC cis rs780096 0.527 rs11127044 chr2:27740404 C/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -6.05 -0.31 3.71e-9 Total body bone mineral density; LIHC trans rs3780486 0.846 rs73484568 chr9:33132492 G/A cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs3736485 0.934 rs7170330 chr15:51859313 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs992157 0.835 rs2292551 chr2:219143229 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.12 -0.55 2.19e-28 Colorectal cancer; LIHC cis rs6882046 0.513 rs187270 chr5:88026870 C/T cg22951263 chr5:87985283 NA -0.39 -6.73 -0.34 7.35e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs6912958 0.703 rs9362427 chr6:88097634 G/T cg08069147 chr6:88032118 GJB7;C6orf162 0.56 10.33 0.49 5.86e-22 Monocyte percentage of white cells; LIHC cis rs7944735 0.508 rs75334064 chr11:47759590 C/T cg20307385 chr11:47447363 PSMC3 -0.54 -5.76 -0.3 1.88e-8 Intraocular pressure; LIHC cis rs12497850 0.543 rs6446218 chr3:49075513 A/T cg06212747 chr3:49208901 KLHDC8B 0.59 7.55 0.38 4e-13 Parkinson's disease; LIHC trans rs9929218 0.551 rs2296408 chr16:68713823 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.88 -19.73 -0.73 2.19e-58 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14196353 chr11:111750159 C11orf1;FDXACB1 0.48 6.38 0.33 5.6e-10 Pancreatic cancer; LIHC cis rs3806843 0.966 rs2563264 chr5:140137503 T/G cg26395211 chr5:140044315 WDR55 0.41 5.98 0.31 5.53e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs3780486 1.000 rs12342831 chr9:33124872 A/G cg04842962 chr6:43655489 MRPS18A 0.94 17.53 0.69 1.51e-49 IgG glycosylation; LIHC cis rs3736485 0.966 rs4775960 chr15:51891698 C/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.34 -0.32 7.32e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11971779 0.680 rs7783619 chr7:139061437 G/A cg07862535 chr7:139043722 LUC7L2 0.6 10.32 0.49 6.32e-22 Diisocyanate-induced asthma; LIHC cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg06481639 chr22:41940642 POLR3H -0.7 -7.03 -0.36 1.14e-11 Vitiligo; LIHC cis rs7647973 0.848 rs4292260 chr3:49148890 T/C cg07636037 chr3:49044803 WDR6 0.72 8.48 0.42 6.69e-16 Menarche (age at onset); LIHC cis rs2742417 0.603 rs2064063 chr3:45759924 T/A cg04837898 chr3:45731254 SACM1L -0.52 -8.67 -0.42 1.75e-16 Response to anti-depressant treatment in major depressive disorder; LIHC trans rs62103177 0.608 rs59300126 chr18:77694439 C/A cg05926928 chr17:57297772 GDPD1 0.82 9.23 0.45 2.89e-18 Opioid sensitivity; LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.22 0.55 9.92e-29 Prudent dietary pattern; LIHC cis rs12701220 0.817 rs1058727 chr7:1087095 A/G cg00990874 chr7:1149470 C7orf50 -0.62 -8.99 -0.44 1.71e-17 Bronchopulmonary dysplasia; LIHC cis rs17106184 0.892 rs12086130 chr1:51173603 C/T cg07174182 chr1:51127561 FAF1 -0.62 -6.85 -0.35 3.53e-11 Type 2 diabetes; LIHC cis rs2153535 0.540 rs9378557 chr6:8517381 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.26e-27 Motion sickness; LIHC cis rs7552404 0.727 rs1159214 chr1:76317910 G/T cg10523679 chr1:76189770 ACADM -0.55 -6.9 -0.35 2.48e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9309473 1.000 rs6546839 chr2:73680508 G/C cg20560298 chr2:73613845 ALMS1 -0.54 -6.83 -0.35 3.84e-11 Metabolite levels; LIHC cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg17554472 chr22:41940697 POLR3H 0.54 5.93 0.31 7.34e-9 Vitiligo; LIHC trans rs11088226 0.538 rs4816436 chr21:33880251 A/G cg09050820 chr6:167586206 TCP10L2 0.49 7.59 0.38 3.08e-13 Gastritis; LIHC cis rs6694270 0.529 rs35941610 chr1:19104930 C/T cg26220594 chr1:19110978 NA -0.36 -6.13 -0.31 2.49e-9 Drug-induced liver injury (nitrofurantoin); LIHC cis rs10751667 0.714 rs7395879 chr11:963855 G/C cg06064525 chr11:970664 AP2A2 -0.56 -14.82 -0.63 1.04e-38 Alzheimer's disease (late onset); LIHC cis rs2279817 1.000 rs10788680 chr1:18019454 A/G cg21791023 chr1:18019539 ARHGEF10L 0.63 8.14 0.4 7.46e-15 Neuroticism; LIHC cis rs9549367 0.774 rs9549696 chr13:113875062 C/T cg18105134 chr13:113819100 PROZ -0.68 -11.55 -0.53 2.86e-26 Platelet distribution width; LIHC trans rs867371 0.826 rs2047678 chr15:82498198 G/A cg18393722 chr15:85113863 UBE2QP1 -0.43 -7.2 -0.36 3.85e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg00684032 chr4:1343700 KIAA1530 0.52 7.57 0.38 3.51e-13 Obesity-related traits; LIHC cis rs644799 0.965 rs3016295 chr11:95554311 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.7 9.97 0.47 1.05e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1707322 0.656 rs2991981 chr1:46057144 A/G cg03146154 chr1:46216737 IPP -0.54 -8.97 -0.44 2.02e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2180341 1.000 rs2038378 chr6:127590400 C/T cg27446573 chr6:127587934 RNF146 1.01 15.07 0.63 1.01e-39 Breast cancer; LIHC cis rs9902453 0.967 rs4473252 chr17:28454423 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.41 0.45 7.5e-19 Coffee consumption (cups per day); LIHC cis rs826838 1.000 rs55828987 chr12:39056421 A/C cg26384229 chr12:38710491 ALG10B 0.87 11.49 0.53 4.51e-26 Heart rate; LIHC cis rs12142240 0.698 rs56284503 chr1:46847127 C/G cg00530320 chr1:46809349 NSUN4 0.53 5.78 0.3 1.68e-8 Menopause (age at onset); LIHC cis rs801193 1.000 rs6975195 chr7:66124774 T/A cg14393609 chr7:65229607 NA -0.37 -5.85 -0.3 1.18e-8 Aortic root size; LIHC cis rs13040088 1.000 rs10854167 chr20:61533039 G/C cg23096297 chr20:61557774 DIDO1 0.82 11.06 0.51 1.64e-24 Menopause (age at onset); LIHC trans rs4714291 0.832 rs1404002 chr6:40064600 C/T cg02267698 chr19:7991119 CTXN1 -0.39 -6.59 -0.34 1.71e-10 Strep throat; LIHC cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg09904177 chr6:26538194 HMGN4 0.5 9.57 0.46 2.14e-19 Intelligence (multi-trait analysis); LIHC cis rs12478296 1.000 rs6732595 chr2:243035338 T/C cg18898632 chr2:242989856 NA -0.55 -7.5 -0.38 5.71e-13 Obesity-related traits; LIHC cis rs11023332 0.832 rs10832289 chr11:14669496 A/T cg25251204 chr11:14927456 NA -0.41 -5.81 -0.3 1.4e-8 Adiponectin levels;Vitamin D levels; LIHC cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg12016809 chr21:47604291 C21orf56 0.49 7.55 0.38 4.03e-13 Testicular germ cell tumor; LIHC cis rs7312933 0.737 rs10880261 chr12:42573822 T/C cg01256987 chr12:42539512 GXYLT1 -0.42 -6.99 -0.35 1.46e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg16132339 chr22:24313637 DDTL;DDT 0.65 11.65 0.53 1.25e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs77861329 1.000 rs9847073 chr3:52144947 C/T cg08692210 chr3:52188851 WDR51A -0.84 -8.2 -0.41 4.76e-15 Macrophage inflammatory protein 1b levels; LIHC cis rs2976388 0.566 rs13250661 chr8:143804134 C/T cg06565975 chr8:143823917 SLURP1 -0.44 -8.04 -0.4 1.46e-14 Urinary tract infection frequency; LIHC cis rs7666738 0.830 rs1834647 chr4:98882915 G/A cg05340658 chr4:99064831 C4orf37 0.67 11.92 0.54 1.23e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs9790314 0.663 rs55888276 chr3:160651406 A/G cg03342759 chr3:160939853 NMD3 0.55 6.5 0.33 2.9e-10 Morning vs. evening chronotype; LIHC cis rs4820294 1.000 rs62236667 chr22:38061520 C/G cg00142150 chr22:38071001 LGALS1 0.7 11.49 0.53 4.61e-26 Fat distribution (HIV); LIHC cis rs9560113 1.000 rs60374273 chr13:112179206 A/T cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs8062405 1.000 rs9972693 chr16:28859802 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7552404 0.765 rs1251078 chr1:76189488 C/G cg10523679 chr1:76189770 ACADM -0.69 -14.38 -0.61 5.3e-37 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6684514 0.506 rs3762281 chr1:156304782 A/G cg07234388 chr1:156261841 TMEM79 0.49 9.03 0.44 1.32e-17 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7116495 1.000 rs560777 chr11:71770602 C/T cg26138937 chr11:71823887 C11orf51 0.8 7.69 0.38 1.53e-13 Severe influenza A (H1N1) infection; LIHC trans rs6058796 1.000 rs13042452 chr20:31240068 T/C cg02600331 chr11:130417168 NA 0.34 6.93 0.35 2.07e-11 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs2710642 0.886 rs10153716 chr2:63007059 A/G cg17519650 chr2:63277830 OTX1 -0.43 -6.74 -0.34 6.91e-11 LDL cholesterol levels;LDL cholesterol; LIHC trans rs2727020 0.894 rs11040333 chr11:49346332 G/A cg15704280 chr7:45808275 SEPT13 -0.74 -11.08 -0.51 1.41e-24 Coronary artery disease; LIHC cis rs35883536 0.647 rs12023028 chr1:101042717 C/T cg14515779 chr1:101123966 NA 0.46 6.6 0.34 1.61e-10 Monocyte count; LIHC cis rs3862030 0.839 rs7078511 chr10:104283874 C/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.57 -0.38 3.52e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs734999 0.545 rs3890745 chr1:2553624 C/T cg18854424 chr1:2615690 NA -0.34 -7.38 -0.37 1.19e-12 Ulcerative colitis; LIHC cis rs875971 0.862 rs778707 chr7:65857027 G/A cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs734999 0.505 rs10797437 chr1:2539006 T/C cg18854424 chr1:2615690 NA 0.33 7.38 0.37 1.23e-12 Ulcerative colitis; LIHC cis rs11792861 0.926 rs75128146 chr9:111833791 G/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 8.86 0.43 4.34e-17 Menarche (age at onset); LIHC cis rs1670533 0.932 rs2248083 chr4:1052166 A/C cg27284194 chr4:1044797 NA 0.6 9.01 0.44 1.46e-17 Recombination rate (females); LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg07157834 chr1:205819609 PM20D1 -0.62 -9.17 -0.44 4.57e-18 Menarche (age at onset); LIHC cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg12379764 chr21:47803548 PCNT -0.62 -9.05 -0.44 1.09e-17 Testicular germ cell tumor; LIHC cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg08888203 chr3:10149979 C3orf24 -0.57 -6.46 -0.33 3.59e-10 Alzheimer's disease; LIHC trans rs783540 0.843 rs9652567 chr15:83368514 T/G cg18393722 chr15:85113863 UBE2QP1 0.37 6.45 0.33 3.72e-10 Schizophrenia; LIHC cis rs56235845 0.964 rs11741640 chr5:176792743 G/A cg06060754 chr5:176797920 RGS14 0.73 11.41 0.53 9.01e-26 Hemoglobin concentration;Hematocrit; LIHC cis rs7208859 0.623 rs9894709 chr17:29078454 G/A cg13385521 chr17:29058706 SUZ12P 0.81 7.96 0.4 2.64e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1499614 1.000 rs2707840 chr7:66158015 C/T cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg11764359 chr7:65958608 NA 0.58 5.87 0.3 1.01e-8 Diabetic kidney disease; LIHC cis rs2455799 0.613 rs6789076 chr3:15807725 A/T cg12698662 chr3:15914712 MIR563 0.4 7.35 0.37 1.48e-12 Mean platelet volume; LIHC cis rs1555322 0.505 rs591590 chr20:33866028 A/G cg07134254 chr20:33865797 NA -0.53 -6.26 -0.32 1.15e-9 Attention deficit hyperactivity disorder; LIHC cis rs875971 0.660 rs7807944 chr7:66087195 C/G cg14393609 chr7:65229607 NA -0.38 -6.04 -0.31 4.01e-9 Aortic root size; LIHC cis rs4891159 0.790 rs10514217 chr18:74144939 A/G cg24786174 chr18:74118243 ZNF516 -0.73 -12.34 -0.56 3.42e-29 Longevity; LIHC cis rs2463822 0.925 rs6863 chr11:62160725 G/T cg06239285 chr11:62104954 ASRGL1 -0.91 -6.55 -0.33 2.07e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs965469 0.779 rs6051772 chr20:3328654 C/G cg25506879 chr20:3388711 C20orf194 -0.53 -6.54 -0.33 2.22e-10 IFN-related cytopenia; LIHC trans rs61931739 0.517 rs12816423 chr12:34067736 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.82 0.35 4.04e-11 Morning vs. evening chronotype; LIHC cis rs11112613 0.609 rs7350593 chr12:106038119 C/T cg03607813 chr12:105948248 NA 0.44 6.9 0.35 2.51e-11 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs10779751 1.000 rs11121710 chr1:11313244 T/C cg08854313 chr1:11322531 MTOR 0.82 11.65 0.53 1.17e-26 Body mass index; LIHC cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg08219700 chr8:58056026 NA 0.53 6.46 0.33 3.64e-10 Developmental language disorder (linguistic errors); LIHC cis rs9911578 1.000 rs12936058 chr17:57017420 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.89e-17 Intelligence (multi-trait analysis); LIHC cis rs60871478 0.635 rs4311567 chr7:792295 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.55 6.31 0.32 8.76e-10 Cerebrospinal P-tau181p levels; LIHC cis rs6831352 0.918 rs2602891 chr4:100043284 C/T cg12011299 chr4:100065546 ADH4 0.61 10.29 0.49 7.89e-22 Alcohol dependence; LIHC cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg26818010 chr10:134567672 INPP5A -0.79 -9.6 -0.46 1.81e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs16944613 0.510 rs8030781 chr15:91143072 T/C cg26821196 chr15:91095069 CRTC3 0.33 6.22 0.32 1.43e-9 Colorectal cancer; LIHC cis rs11229555 0.645 rs7931394 chr11:58212617 T/A cg15696309 chr11:58395628 NA -0.65 -7.63 -0.38 2.37e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs921968 0.528 rs13382651 chr2:219628191 A/G cg02985541 chr2:219472218 PLCD4 -0.38 -6.57 -0.33 1.83e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg03721293 chr16:90014378 DEF8 0.41 6.89 0.35 2.62e-11 Skin colour saturation; LIHC cis rs11628318 0.508 rs3950014 chr14:103069889 G/A cg01864069 chr14:103024347 NA -0.47 -7.45 -0.37 7.91e-13 Platelet count; LIHC cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.3 -6.12 -0.31 2.59e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs6542838 0.704 rs56125264 chr2:99516699 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.68 -0.34 9.41e-11 Fear of minor pain; LIHC cis rs1552244 0.572 rs68121641 chr3:10165845 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs2842992 0.789 rs4709370 chr6:160210061 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.51 0.42 5.56e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs6951245 0.554 rs10270249 chr7:1151886 G/T cg22907277 chr7:1156413 C7orf50 0.81 7.69 0.38 1.63e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4975616 0.869 rs452932 chr5:1330253 T/C cg07493874 chr5:1342172 CLPTM1L -0.68 -10.92 -0.51 5.23e-24 Lung cancer; LIHC cis rs709400 0.628 rs7155014 chr14:103863970 C/G cg26031613 chr14:104095156 KLC1 0.71 9.13 0.44 5.97e-18 Body mass index; LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs3768617 0.528 rs6672093 chr1:183079853 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.3 0.49 7.49e-22 Fuchs's corneal dystrophy; LIHC cis rs6762 0.719 rs28655651 chr11:837121 G/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.8 -0.47 3.82e-20 Mean platelet volume; LIHC cis rs240764 0.621 rs6570930 chr6:101181258 C/A cg12253828 chr6:101329408 ASCC3 -0.39 -5.97 -0.31 6.04e-9 Neuroticism; LIHC trans rs6952808 0.825 rs4236277 chr7:1942270 C/T cg04565464 chr8:145669602 NFKBIL2 0.39 6.09 0.31 3.12e-9 Bipolar disorder and schizophrenia; LIHC cis rs17253792 0.545 rs35466279 chr14:56017022 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs2303759 0.670 rs45549132 chr19:49794028 G/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.58 8.6 0.42 2.91e-16 Multiple sclerosis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01699524 chr5:7869638 MTRR;FASTKD3 -0.5 -6.03 -0.31 4.16e-9 Systolic blood pressure; LIHC cis rs10504229 0.906 rs7846666 chr8:58172302 T/C cg21724239 chr8:58056113 NA 0.46 6.08 0.31 3.23e-9 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg10802521 chr3:52805072 NEK4 -0.44 -7.35 -0.37 1.45e-12 Bipolar disorder; LIHC cis rs2243480 1.000 rs778704 chr7:65863467 T/C cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs936229 0.749 rs8031937 chr15:75181121 A/G cg10253484 chr15:75165896 SCAMP2 -0.59 -6.93 -0.35 2.17e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs116095464 0.558 rs62346506 chr5:201594 T/C cg22857025 chr5:266934 NA -1.64 -16.58 -0.67 1.01e-45 Breast cancer; LIHC cis rs853679 0.517 rs2281588 chr6:28072602 G/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs10910092 1 rs10910092 chr1:2501516 A/G cg18854424 chr1:2615690 NA 0.31 6.73 0.34 7.28e-11 Ulcerative colitis; LIHC cis rs34779708 0.931 rs79749947 chr10:35277081 A/T cg03585969 chr10:35415529 CREM 0.87 13.04 0.58 7.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4474465 1.000 rs7106080 chr11:78150592 G/A cg27205649 chr11:78285834 NARS2 -0.39 -5.93 -0.31 7.3e-9 Alzheimer's disease (survival time); LIHC cis rs2455799 0.613 rs12485852 chr3:15914511 G/C cg12698662 chr3:15914712 MIR563 -0.4 -7.51 -0.38 5.11e-13 Mean platelet volume; LIHC cis rs2645694 0.626 rs2645704 chr4:77830805 T/C cg06046430 chr4:77819534 ANKRD56 0.51 6.26 0.32 1.12e-9 Emphysema distribution in smoking; LIHC trans rs8073060 0.963 rs4795082 chr17:33873501 C/T cg19694781 chr19:47549865 TMEM160 0.68 7.16 0.36 5.09e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9486715 0.867 rs7451950 chr6:96879974 T/C cg06623918 chr6:96969491 KIAA0776 0.86 14.92 0.63 4.06e-39 Headache; LIHC cis rs910316 1.000 rs175426 chr14:75624134 C/T cg08847533 chr14:75593920 NEK9 -0.87 -18.79 -0.71 1.34e-54 Height; LIHC cis rs875971 0.830 rs28714531 chr7:65968237 G/A cg18876405 chr7:65276391 NA 0.34 6.18 0.32 1.8e-9 Aortic root size; LIHC cis rs367615 0.704 rs4286723 chr5:108835959 G/A cg17395555 chr5:108820864 NA 0.4 8.71 0.43 1.34e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg12756686 chr19:29218302 NA 0.43 6.64 0.34 1.24e-10 Methadone dose in opioid dependence; LIHC trans rs2727020 0.755 rs652655 chr11:49251293 G/A cg15704280 chr7:45808275 SEPT13 0.89 16.18 0.66 4.13e-44 Coronary artery disease; LIHC cis rs7772486 0.875 rs6934467 chr6:146410529 G/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.29 -0.32 9.94e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs55665837 1.000 rs12295888 chr11:14450531 T/C cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs992157 0.775 rs7559428 chr2:219150238 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.78 -12.32 -0.55 4.18e-29 Colorectal cancer; LIHC cis rs12095069 1 rs12095069 chr1:76463072 T/C cg03433033 chr1:76189801 ACADM 0.51 7.48 0.38 6.2800000000000005e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs870825 0.929 rs72689254 chr4:185589941 C/T cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs1008375 0.897 rs6820164 chr4:17630115 G/A cg16339924 chr4:17578868 LAP3 0.53 7.05 0.36 1.03e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg05564831 chr3:52568323 NT5DC2 0.35 5.83 0.3 1.27e-8 Bipolar disorder; LIHC cis rs9399135 0.967 rs952674 chr6:135349157 A/G cg24558204 chr6:135376177 HBS1L 0.42 6.86 0.35 3.16e-11 Red blood cell count; LIHC cis rs73001065 0.901 rs3794991 chr19:19610596 C/T cg03709012 chr19:19516395 GATAD2A 0.89 7.85 0.39 5.53e-14 LDL cholesterol; LIHC cis rs1997103 0.954 rs2030807 chr7:55378485 A/G cg17469321 chr7:55412551 NA 0.49 7.15 0.36 5.38e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9457247 1.000 rs407515 chr6:167407544 G/C cg23791538 chr6:167370224 RNASET2 -0.64 -10.9 -0.51 6.13e-24 Crohn's disease; LIHC trans rs975809 0.966 rs11004607 chr10:56622686 G/T cg06521597 chr19:2783551 SGTA 0.42 6.21 0.32 1.56e-9 Carotid intima media thickness; LIHC cis rs3008870 1.000 rs3008888 chr1:67368965 C/T cg02640540 chr1:67518911 SLC35D1 0.44 5.96 0.31 6.15e-9 Lymphocyte percentage of white cells; LIHC cis rs1419980 0.730 rs7978534 chr12:7773878 C/T cg10578777 chr12:7781093 NA -0.39 -5.79 -0.3 1.55e-8 HDL cholesterol levels; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg09033563 chr22:24373618 LOC391322 -0.66 -9.67 -0.46 1.05e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg18279126 chr7:2041391 MAD1L1 0.39 6.43 0.33 4.19e-10 Bipolar disorder and schizophrenia; LIHC cis rs16828019 0.640 rs1140227 chr1:41493811 C/T cg03387723 chr1:41708464 SCMH1 -0.41 -6.62 -0.34 1.39e-10 Intelligence (multi-trait analysis); LIHC cis rs600806 0.683 rs10857788 chr1:110012289 G/A cg10127483 chr1:110009974 SYPL2 0.5 6.4 0.33 5.26e-10 Intelligence (multi-trait analysis); LIHC cis rs2075371 0.796 rs1646644 chr7:134011817 A/T cg20476274 chr7:133979776 SLC35B4 0.62 10.3 0.49 7.4e-22 Mean platelet volume; LIHC cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.7 -11.61 -0.53 1.73e-26 Age at first birth; LIHC cis rs875971 0.929 rs34406470 chr7:65929956 A/G cg18876405 chr7:65276391 NA 0.39 6.99 0.35 1.48e-11 Aortic root size; LIHC cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg03517284 chr6:25882590 NA -0.48 -7.32 -0.37 1.73e-12 Height; LIHC cis rs35306767 0.855 rs61830932 chr10:934183 T/C cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs9549328 0.670 rs2873372 chr13:113613383 A/G cg18289306 chr13:113640169 MCF2L 0.37 6.15 0.32 2.14e-9 Systolic blood pressure; LIHC cis rs9430161 0.611 rs72644043 chr1:11033051 T/A cg27631724 chr1:11040367 C1orf127 0.37 6.74 0.34 6.67e-11 Ewing sarcoma; LIHC trans rs5756813 0.727 rs13055462 chr22:38184685 A/G cg19894588 chr14:64061835 NA -0.65 -9.13 -0.44 6.03e-18 Optic cup area;Vertical cup-disc ratio; LIHC cis rs17125944 0.686 rs7149638 chr14:53346931 T/C cg00686598 chr14:53173677 PSMC6 -0.8 -8.86 -0.43 4.35e-17 Alzheimer's disease (late onset); LIHC cis rs6952808 0.609 rs4721190 chr7:1954732 A/G cg04267008 chr7:1944627 MAD1L1 0.67 10.64 0.5 5.13e-23 Bipolar disorder and schizophrenia; LIHC cis rs17253792 0.822 rs77544029 chr14:56087917 T/C cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs12824058 1.000 rs12824058 chr12:130804334 A/G cg24838063 chr12:130822603 PIWIL1 0.65 9.2 0.45 3.5e-18 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09400194 chr10:81107848 PPIF 0.44 6.41 0.33 4.97e-10 Pancreatic cancer; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs2806561 0.765 rs652783 chr1:23514313 G/T cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.49e-11 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23633679 chr1:173793655 CENPL;DARS2 0.49 7.41 0.37 9.91e-13 Cognitive function; LIHC cis rs7617773 0.817 rs9819094 chr3:48319558 C/T cg11946769 chr3:48343235 NME6 0.86 11.46 0.53 5.78e-26 Coronary artery disease; LIHC cis rs10256972 0.647 rs10233430 chr7:1051664 T/C cg16145915 chr7:1198662 ZFAND2A -0.26 -6.11 -0.31 2.71e-9 Longevity;Endometriosis; LIHC cis rs9522267 0.737 rs9515455 chr13:112239671 A/G cg10483660 chr13:112241077 NA 0.24 6.07 0.31 3.36e-9 Hepatitis; LIHC cis rs870825 0.549 rs7656993 chr4:185635159 T/C cg04058563 chr4:185651563 MLF1IP 0.69 7.21 0.36 3.66e-12 Blood protein levels; LIHC cis rs5769765 1.000 rs2092982 chr22:50282204 C/A cg02269571 chr22:50332266 NA 0.61 8.64 0.42 2.24e-16 Schizophrenia; LIHC cis rs2304069 0.545 rs1864998 chr5:149389465 C/T cg12661370 chr5:149340060 SLC26A2 0.55 8.24 0.41 3.7e-15 HIV-1 control; LIHC cis rs7412746 0.611 rs752376 chr1:150941381 C/T cg15448220 chr1:150897856 SETDB1 0.38 6.13 0.31 2.46e-9 Melanoma; LIHC cis rs6500602 0.826 rs11076830 chr16:4460049 A/G cg08645402 chr16:4508243 NA 0.34 5.83 0.3 1.26e-8 Schizophrenia; LIHC cis rs11122272 0.638 rs2739514 chr1:231514806 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.19e-18 Hemoglobin concentration; LIHC cis rs11229555 0.645 rs7930547 chr11:58197616 A/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs16854884 0.586 rs6795008 chr3:143738421 A/G cg06585982 chr3:143692056 C3orf58 0.58 7.51 0.38 5.11e-13 Economic and political preferences (feminism/equality); LIHC cis rs240764 0.658 rs12213201 chr6:101176285 C/A cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.49e-9 Neuroticism; LIHC cis rs1552244 0.510 rs13075308 chr3:10034925 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs13108904 0.557 rs1250098 chr4:1238256 A/T cg19318889 chr4:1322082 MAEA -0.62 -9.98 -0.47 9.33e-21 Obesity-related traits; LIHC cis rs7224737 1.000 rs8074708 chr17:40286354 A/G cg20291162 chr17:40259547 DHX58 0.4 6.45 0.33 3.71e-10 Fibrinogen levels; LIHC cis rs4950322 0.512 rs2883318 chr1:146849143 A/C cg25205988 chr1:146714368 CHD1L -0.42 -5.95 -0.31 6.66e-9 Protein quantitative trait loci; LIHC cis rs35306767 0.903 rs17159950 chr10:875287 T/G cg20503657 chr10:835505 NA 1.09 12.06 0.55 3.66e-28 Eosinophil percentage of granulocytes; LIHC cis rs2153535 0.562 rs9379211 chr6:8463927 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs208520 0.690 rs1351867 chr6:66760995 A/G cg07460842 chr6:66804631 NA 0.81 9.25 0.45 2.56e-18 Exhaled nitric oxide output; LIHC cis rs34172651 0.876 rs1862451 chr16:24803620 A/G cg00339695 chr16:24857497 SLC5A11 0.54 8.23 0.41 4e-15 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg06873352 chr17:61820015 STRADA 0.74 13.62 0.59 4.81e-34 Prudent dietary pattern; LIHC cis rs2066819 0.901 rs773665 chr12:56717466 C/T cg26714650 chr12:56694279 CS 1.26 15.31 0.64 1.14e-40 Psoriasis vulgaris; LIHC cis rs317689 0.690 rs618470 chr12:69672060 A/G cg22834771 chr12:69754056 YEATS4 -0.39 -5.84 -0.3 1.24e-8 Response to diuretic therapy; LIHC cis rs240764 0.817 rs239221 chr6:101113085 G/A cg09795085 chr6:101329169 ASCC3 0.52 7.4 0.37 1.06e-12 Neuroticism; LIHC cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.667 rs7282122 chr21:45082365 G/A cg04455712 chr21:45112962 RRP1B 0.54 9.33 0.45 1.39e-18 Mean corpuscular volume; LIHC cis rs7772486 0.875 rs6909827 chr6:146365738 A/G cg13319975 chr6:146136371 FBXO30 -0.34 -5.81 -0.3 1.44e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs992157 1.000 rs2292553 chr2:219146803 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.82 13.2 0.58 1.95e-32 Colorectal cancer; LIHC cis rs2292884 0.505 rs78063959 chr2:238428961 G/A cg08992911 chr2:238395768 MLPH 0.55 6.44 0.33 4.12e-10 Prostate cancer; LIHC cis rs853679 0.517 rs3757187 chr6:28107654 T/C cg16479474 chr6:28041457 NA 0.46 6.58 0.34 1.78e-10 Depression; LIHC cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg23262073 chr20:60523788 NA 0.31 6.26 0.32 1.15e-9 Body mass index; LIHC cis rs12286929 0.609 rs12417740 chr11:115098436 A/G cg04055981 chr11:115044050 NA -0.43 -6.29 -0.32 9.59e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1348850 0.750 rs55792594 chr2:178496468 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 7.86 0.39 4.96e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12701220 0.655 rs6463317 chr7:1159243 G/A cg04025307 chr7:1156635 C7orf50 0.54 7.3 0.37 2.02e-12 Bronchopulmonary dysplasia; LIHC cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg07308232 chr7:1071921 C7orf50 -0.56 -9.1 -0.44 7.76e-18 Longevity;Endometriosis; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg09328466 chr7:64023458 ZNF680 -0.38 -6.1 -0.31 2.85e-9 Immature fraction of reticulocytes; LIHC cis rs7647973 0.961 rs6778080 chr3:49317338 C/T cg07636037 chr3:49044803 WDR6 -0.47 -5.94 -0.31 6.94e-9 Menarche (age at onset); LIHC trans rs875971 1.000 rs778722 chr7:65844828 T/C cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs739401 0.611 rs2301140 chr11:3022629 C/T cg08508325 chr11:3079039 CARS -0.29 -5.88 -0.3 9.92e-9 Longevity; LIHC cis rs9486715 0.758 rs2971610 chr6:97027380 C/T cg18709589 chr6:96969512 KIAA0776 -0.32 -5.72 -0.3 2.29e-8 Headache; LIHC cis rs74233809 1.000 rs11191555 chr10:104857523 A/C cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.43e-9 Birth weight; LIHC cis rs238295 0.805 rs6038214 chr20:5569822 C/G cg24001556 chr20:5591874 RP5-1022P6.2 0.51 7.01 0.35 1.31e-11 Occipital cortical area (total cortical area interaction); LIHC trans rs1814175 0.765 rs1722003 chr11:49895896 G/A cg03929089 chr4:120376271 NA -0.9 -18.35 -0.7 7.75e-53 Height; LIHC cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg11987759 chr7:65425863 GUSB 0.38 5.97 0.31 5.84e-9 Aortic root size; LIHC cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg18279126 chr7:2041391 MAD1L1 0.35 5.88 0.3 9.92e-9 Bipolar disorder and schizophrenia; LIHC trans rs7714584 1.000 rs11746108 chr5:150264622 C/A cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08081407 chr3:57583693 ARF4 0.53 7.5 0.38 5.71e-13 Lung function (FEV1/FVC); LIHC cis rs2075371 1.000 rs2598291 chr7:133988313 C/G cg20476274 chr7:133979776 SLC35B4 0.75 12.73 0.57 1.22e-30 Mean platelet volume; LIHC trans rs783540 0.609 rs803686 chr15:83219340 G/A cg18393722 chr15:85113863 UBE2QP1 -0.46 -6.98 -0.35 1.55e-11 Schizophrenia; LIHC cis rs2997447 0.802 rs61776621 chr1:26459058 C/G cg19633962 chr1:26362018 EXTL1 -0.65 -5.76 -0.3 1.87e-8 QRS complex (12-leadsum); LIHC cis rs116095464 0.558 rs73029475 chr5:206969 T/C cg22496380 chr5:211416 CCDC127 -1.19 -10.49 -0.49 1.66e-22 Breast cancer; LIHC cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg13047869 chr3:10149882 C3orf24 0.52 6.18 0.32 1.81e-9 Alzheimer's disease; LIHC cis rs10751667 0.666 rs7395267 chr11:962326 C/A cg10932868 chr11:921992 NA 0.39 7.25 0.37 2.71e-12 Alzheimer's disease (late onset); LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg04025307 chr7:1156635 C7orf50 0.54 7.09 0.36 7.73e-12 Bronchopulmonary dysplasia; LIHC cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg10360323 chr17:41437877 NA 0.4 5.98 0.31 5.76e-9 Menopause (age at onset); LIHC cis rs921968 0.643 rs2178019 chr2:219316303 G/A cg17980119 chr2:219472607 PLCD4 0.36 6.19 0.32 1.72e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7474896 0.522 rs117157955 chr10:37984164 G/T cg25427524 chr10:38739819 LOC399744 -0.49 -7.22 -0.36 3.35e-12 Obesity (extreme); LIHC cis rs9916302 0.904 rs4795359 chr17:37573146 C/T cg03013999 chr17:37608204 MED1 0.35 5.8 0.3 1.49e-8 Glomerular filtration rate (creatinine); LIHC cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg03517284 chr6:25882590 NA -0.63 -8.95 -0.44 2.28e-17 Blood metabolite levels; LIHC cis rs6840360 0.550 rs6535806 chr4:152483906 G/A cg22705602 chr4:152727874 NA -0.33 -6.49 -0.33 2.93e-10 Intelligence (multi-trait analysis); LIHC cis rs9858542 0.953 rs6803222 chr3:49665976 T/G cg03060546 chr3:49711283 APEH -0.6 -7.97 -0.4 2.35e-14 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs10089 0.904 rs3087889 chr5:127524944 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.52 6.45 0.33 3.81e-10 Ileal carcinoids; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10659575 chr11:102188233 BIRC3 0.46 7.49 0.38 6.03e-13 Cognitive function; LIHC cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg11764359 chr7:65958608 NA -0.57 -5.92 -0.31 7.72e-9 Diabetic kidney disease; LIHC cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg03264133 chr6:25882463 NA 0.53 6.64 0.34 1.2e-10 Intelligence (multi-trait analysis); LIHC cis rs10420951 0.579 rs79341622 chr19:18598213 T/C cg10790698 chr19:18539756 SSBP4 -0.42 -5.99 -0.31 5.44e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs57502260 1.000 rs57502260 chr11:68220905 A/G cg16797656 chr11:68205561 LRP5 0.59 8.18 0.4 5.52e-15 Total body bone mineral density (age 45-60); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19748516 chr19:18684528 UBA52 -0.45 -7.0 -0.35 1.34e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11673344 0.670 rs505717 chr19:37430316 A/G cg27390819 chr19:37464633 NA -0.5 -6.01 -0.31 4.88e-9 Obesity-related traits; LIHC cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs637571 0.726 rs526631 chr11:65681965 T/G cg26695010 chr11:65641043 EFEMP2 0.45 6.25 0.32 1.22e-9 Eosinophil percentage of white cells; LIHC cis rs7249142 0.562 rs11085253 chr19:19277517 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -6.8 -0.35 4.56e-11 IgG glycosylation; LIHC cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg06634786 chr22:41940651 POLR3H -0.73 -7.12 -0.36 6.34e-12 Vitiligo; LIHC cis rs614226 0.748 rs78714658 chr12:121009944 G/A cg01236616 chr12:121019343 POP5 -1.32 -17.01 -0.68 1.81e-47 Type 1 diabetes nephropathy; LIHC cis rs2153535 0.580 rs1932285 chr6:8477719 T/G cg07606381 chr6:8435919 SLC35B3 0.82 12.33 0.55 3.65e-29 Motion sickness; LIHC cis rs9660992 0.573 rs7368327 chr1:205214792 C/T cg21545522 chr1:205238299 TMCC2 0.38 7.17 0.36 4.66e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2304069 0.545 rs11167492 chr5:149403101 G/A cg12661370 chr5:149340060 SLC26A2 0.54 8.06 0.4 1.34e-14 HIV-1 control; LIHC cis rs9918079 0.506 rs7696127 chr4:15642953 T/A cg21329975 chr4:15471214 CC2D2A -0.41 -6.19 -0.32 1.69e-9 Obesity-related traits; LIHC cis rs7904368 0.806 rs4612698 chr10:16855070 C/A cg23933602 chr10:16859644 RSU1 0.59 5.81 0.3 1.42e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs6840360 0.806 rs11932383 chr4:152716136 T/C cg22705602 chr4:152727874 NA 0.31 6.52 0.33 2.51e-10 Intelligence (multi-trait analysis); LIHC cis rs74544699 1.000 rs938094 chr4:74805942 C/G cg02530824 chr4:74847766 PF4 0.6 6.3 0.32 9.31e-10 Growth-regulated protein alpha levels; LIHC cis rs7116495 0.609 rs2503 chr11:71719403 C/T cg26138937 chr11:71823887 C11orf51 1.35 11.5 0.53 4.41e-26 Severe influenza A (H1N1) infection; LIHC cis rs10744422 1.000 rs2135014 chr12:123333065 C/T cg18912006 chr12:123335444 HIP1R -0.63 -7.64 -0.38 2.14e-13 Schizophrenia; LIHC trans rs1945213 0.694 rs12222077 chr11:55848116 T/A cg15704280 chr7:45808275 SEPT13 0.59 7.58 0.38 3.25e-13 Acute lymphoblastic leukemia (childhood); LIHC trans rs1814175 0.817 rs7924619 chr11:49620632 G/A cg03929089 chr4:120376271 NA -0.89 -18.28 -0.7 1.41e-52 Height; LIHC trans rs1499614 0.901 rs3936 chr7:66126489 C/T cg10756647 chr7:56101905 PSPH 1.01 11.86 0.54 2.03e-27 Gout; LIHC cis rs899997 0.814 rs28661610 chr15:78985317 G/A cg04896959 chr15:78267971 NA -0.4 -7.01 -0.35 1.29e-11 Coronary artery disease or large artery stroke; LIHC cis rs2153535 0.547 rs9502720 chr6:8541362 C/A cg23788917 chr6:8435910 SLC35B3 0.61 8.51 0.42 5.35e-16 Motion sickness; LIHC cis rs611744 0.669 rs13251024 chr8:109258333 T/C cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg25405998 chr7:65216604 CCT6P1 0.44 6.52 0.33 2.47e-10 Calcium levels; LIHC cis rs1552244 0.882 rs13084194 chr3:10031492 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.58 -8.19 -0.4 5.24e-15 Alzheimer's disease; LIHC cis rs7582720 1.000 rs76298043 chr2:203814694 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2268241 0.938 rs17878783 chr21:34779185 G/A cg14850771 chr21:34775459 IFNGR2 0.91 13.79 0.6 1.02e-34 Obesity-related traits; LIHC cis rs611744 0.967 rs653633 chr8:109196151 T/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC trans rs2243480 1.000 rs422164 chr7:65586605 C/G cg10756647 chr7:56101905 PSPH 1.08 13.39 0.59 3.64e-33 Diabetic kidney disease; LIHC cis rs11971779 0.941 rs6954453 chr7:139031794 C/T cg07862535 chr7:139043722 LUC7L2 0.68 11.08 0.51 1.41e-24 Diisocyanate-induced asthma; LIHC cis rs1816752 0.870 rs7998797 chr13:25014988 A/C cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC trans rs561341 1.000 rs55978022 chr17:30275937 T/C cg20587970 chr11:113659929 NA -1.41 -11.54 -0.53 2.99e-26 Hip circumference adjusted for BMI; LIHC cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg05590025 chr7:65112418 INTS4L2 0.67 7.36 0.37 1.34e-12 Diabetic kidney disease; LIHC cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg11644478 chr21:40555479 PSMG1 0.84 10.77 0.5 1.74e-23 Cognitive function; LIHC cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg25894440 chr7:65020034 NA -0.55 -6.36 -0.33 6.33e-10 Diabetic kidney disease; LIHC cis rs7914558 0.646 rs7909591 chr10:104659018 G/T cg15744005 chr10:104629667 AS3MT -0.35 -7.2 -0.36 3.87e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1385374 0.858 rs3765107 chr12:129278310 A/G cg21616243 chr12:129299702 MGC16384;SLC15A4 0.59 7.25 0.37 2.78e-12 Systemic lupus erythematosus; LIHC cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 9.13 0.44 6.13e-18 Mean platelet volume; LIHC cis rs7106204 0.748 rs4360697 chr11:24217160 A/G ch.11.24196551F chr11:24239977 NA 0.77 10.41 0.49 3.03e-22 Response to Homoharringtonine (cytotoxicity); LIHC cis rs875971 0.540 rs781152 chr7:65479572 T/A cg14393609 chr7:65229607 NA 0.43 6.16 0.32 2.05e-9 Aortic root size; LIHC cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC trans rs801193 1.000 rs1553609 chr7:66197139 T/C cg26939375 chr7:64535504 NA 0.42 6.75 0.34 6.45e-11 Aortic root size; LIHC cis rs11077998 0.967 rs4789786 chr17:80504352 A/G cg10255544 chr17:80519551 FOXK2 -0.47 -8.63 -0.42 2.41e-16 Reticulocyte fraction of red cells; LIHC cis rs7739232 0.920 rs7748828 chr6:53517643 A/C cg19801120 chr6:53530570 KLHL31 -0.9 -6.21 -0.32 1.57e-9 Hip circumference adjusted for BMI; LIHC cis rs910316 0.591 rs7157158 chr14:75457238 A/G cg08847533 chr14:75593920 NEK9 0.89 18.43 0.71 3.71e-53 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15543284 chr2:54785307 SPTBN1 0.48 7.07 0.36 8.52e-12 Lung function (FEV1/FVC); LIHC trans rs56011263 0.687 rs73221103 chr4:706740 T/C cg12575136 chr18:32820987 ZNF397 0.48 7.2 0.36 3.8e-12 White blood cell count; LIHC cis rs6840360 0.550 rs11723438 chr4:152531801 C/T cg22705602 chr4:152727874 NA 0.33 6.4 0.33 5.01e-10 Intelligence (multi-trait analysis); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg19947233 chr4:90032727 TIGD2 -0.44 -6.17 -0.32 1.92e-9 Alopecia areata; LIHC cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs11098499 0.909 rs28571712 chr4:120375980 G/A cg09307838 chr4:120376055 NA 0.77 12.14 0.55 1.93e-28 Corneal astigmatism; LIHC cis rs17401966 0.931 rs34225619 chr1:10371987 C/T cg15208524 chr1:10270712 KIF1B 0.45 6.69 0.34 8.9e-11 Hepatocellular carcinoma; LIHC cis rs6442522 0.966 rs6792128 chr3:15458857 A/G cg16303742 chr3:15540471 COLQ 0.41 6.94 0.35 1.92e-11 Uric acid levels; LIHC cis rs1419980 0.730 rs11054866 chr12:7770533 T/C cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs35883536 0.588 rs17403878 chr1:101105310 C/T cg14515779 chr1:101123966 NA -0.57 -10.7 -0.5 3.14e-23 Monocyte count; LIHC cis rs2380220 0.935 rs7748857 chr6:96001887 A/G cg15832292 chr6:96025679 MANEA 0.54 7.08 0.36 8.22e-12 Behavioural disinhibition (generation interaction); LIHC cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg19318889 chr4:1322082 MAEA 0.42 6.42 0.33 4.49e-10 Longevity; LIHC cis rs2153535 0.560 rs2210798 chr6:8481522 C/T cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs8078723 1.000 rs56922390 chr17:38157021 C/G cg17467752 chr17:38218738 THRA 0.76 13.98 0.6 1.96e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs55823223 0.564 rs12103594 chr17:73855279 C/T cg14829360 chr17:73884958 NA -0.56 -8.24 -0.41 3.64e-15 Psoriasis; LIHC cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg10883421 chr6:151773342 RMND1;C6orf211 0.78 14.91 0.63 4.59e-39 Menarche (age at onset); LIHC trans rs1005277 0.579 rs2472175 chr10:38382901 T/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs561341 0.714 rs55925849 chr17:30253085 C/T cg20587970 chr11:113659929 NA -1.47 -11.82 -0.54 2.81e-27 Hip circumference adjusted for BMI; LIHC cis rs7572733 0.555 rs2164071 chr2:198915467 T/C cg10820045 chr2:198174542 NA 0.4 5.92 0.3 7.95e-9 Dermatomyositis; LIHC cis rs12594515 1.000 rs57299255 chr15:45996532 C/A cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs6912958 0.535 rs1753154 chr6:88032843 G/C cg08069147 chr6:88032118 GJB7;C6orf162 0.6 11.33 0.52 1.76e-25 Monocyte percentage of white cells; LIHC cis rs9560113 0.960 rs9560102 chr13:112173825 G/A cg14154082 chr13:112174009 NA 0.29 6.1 0.31 2.81e-9 Menarche (age at onset); LIHC cis rs4713118 0.513 rs9368547 chr6:28028067 A/G cg16479474 chr6:28041457 NA 0.38 6.32 0.32 8.32e-10 Parkinson's disease; LIHC trans rs12478296 0.581 rs4973645 chr2:242993577 T/C cg01596870 chr19:55963115 NA -0.6 -7.67 -0.38 1.83e-13 Obesity-related traits; LIHC cis rs12602172 1 rs12602172 chr17:38163567 G/A cg17467752 chr17:38218738 THRA 0.76 13.99 0.6 1.82e-35 Neutrophil percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs35306767 0.633 rs17221491 chr10:1065191 A/G cg20503657 chr10:835505 NA 0.75 7.02 0.35 1.22e-11 Eosinophil percentage of granulocytes; LIHC cis rs3106136 0.903 rs67552174 chr4:95203097 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.81 -0.39 6.87e-14 Capecitabine sensitivity; LIHC cis rs6426558 0.515 rs7521110 chr1:227384459 T/A cg10327440 chr1:227177885 CDC42BPA -0.42 -6.48 -0.33 3.23e-10 Neutrophil percentage of white cells; LIHC cis rs344364 0.511 rs911391 chr16:1947016 C/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.42 -0.37 9.58e-13 Glomerular filtration rate in chronic kidney disease; LIHC cis rs9583531 0.600 rs6492305 chr13:111361400 C/T cg15841412 chr13:111365552 ING1 0.47 5.87 0.3 1.04e-8 Coronary artery disease; LIHC cis rs1997103 1.000 rs9642578 chr7:55400320 A/G cg17469321 chr7:55412551 NA 0.48 7.0 0.35 1.38e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2404602 0.536 rs7165025 chr15:76766434 G/A cg03037974 chr15:76606532 NA 0.76 14.77 0.62 1.62e-38 Blood metabolite levels; LIHC cis rs1451375 0.617 rs17733244 chr7:50575495 T/C cg14593290 chr7:50529359 DDC 0.64 9.98 0.47 9.69e-21 Malaria; LIHC cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06463759 chr7:128502823 ATP6V1F 0.55 7.9 0.39 3.9e-14 Lung function (FEV1/FVC); LIHC cis rs6912958 1.000 rs6933587 chr6:88175577 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.2 -0.36 3.86e-12 Monocyte percentage of white cells; LIHC cis rs5769765 0.624 rs138843 chr22:50183162 C/T cg02269571 chr22:50332266 NA -0.57 -7.6 -0.38 2.85e-13 Schizophrenia; LIHC cis rs7592578 0.508 rs62180987 chr2:191267173 A/G cg10560079 chr2:191398806 TMEM194B -0.69 -9.84 -0.47 2.74e-20 Diastolic blood pressure; LIHC cis rs858239 0.539 rs4365988 chr7:23190871 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.83 0.35 3.89e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs477895 0.713 rs3802933 chr11:63988102 C/T cg04317338 chr11:64019027 PLCB3 0.84 10.22 0.48 1.43e-21 Mean platelet volume; LIHC cis rs7027203 0.828 rs10761288 chr9:96609363 C/T cg14598338 chr9:96623480 NA -0.32 -6.44 -0.33 4.09e-10 DNA methylation (variation); LIHC cis rs10411936 0.785 rs2363120 chr19:16519871 C/A cg10248733 chr19:16607483 C19orf44;CALR3 -0.43 -5.92 -0.31 7.69e-9 White blood cell count;Multiple sclerosis; LIHC cis rs7552404 1.000 rs437298 chr1:76113770 T/C cg10523679 chr1:76189770 ACADM -0.64 -8.79 -0.43 7.59e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10927875 0.632 rs6699394 chr1:16145143 C/A cg07117364 chr1:16154769 NA -0.39 -6.98 -0.35 1.52e-11 Dilated cardiomyopathy; LIHC cis rs870825 0.616 rs6810635 chr4:185616859 T/C cg04058563 chr4:185651563 MLF1IP 0.72 7.26 0.37 2.7e-12 Blood protein levels; LIHC cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg23758822 chr17:41437982 NA 0.93 17.08 0.68 1.03e-47 Menopause (age at onset); LIHC trans rs5756813 0.833 rs5756819 chr22:38188195 A/C cg19894588 chr14:64061835 NA 0.67 9.94 0.47 1.31e-20 Optic cup area;Vertical cup-disc ratio; LIHC cis rs4671400 0.543 rs62152274 chr2:61499588 C/A cg14146966 chr2:61757674 XPO1 -0.37 -5.86 -0.3 1.1e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs7617773 0.832 rs6775114 chr3:48182620 G/C cg11946769 chr3:48343235 NME6 -0.57 -7.63 -0.38 2.28e-13 Coronary artery disease; LIHC cis rs2304069 0.954 rs216127 chr5:149428890 A/G cg12661370 chr5:149340060 SLC26A2 0.5 5.89 0.3 9.34e-9 HIV-1 control; LIHC cis rs9916302 0.706 rs9944459 chr17:37484185 T/C cg07936489 chr17:37558343 FBXL20 0.85 12.38 0.56 2.46e-29 Glomerular filtration rate (creatinine); LIHC cis rs9837602 0.507 rs793448 chr3:99532949 G/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.8 -0.3 1.53e-8 Breast cancer; LIHC cis rs6450176 0.909 rs7732139 chr5:53292017 G/A ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.29 -0.64 1.35e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.61 8.63 0.42 2.28e-16 Lymphocyte counts; LIHC cis rs4065321 0.522 rs3744245 chr17:38146542 C/G cg17344932 chr17:38183730 MED24;SNORD124 0.77 15.18 0.63 3.75e-40 White blood cell count (basophil);White blood cell count; LIHC cis rs7903847 0.642 rs10882915 chr10:99142184 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 9.11 0.44 6.86e-18 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10352719 chr14:24769404 DHRS1;C14orf21 0.43 6.68 0.34 9.52e-11 Cognitive function; LIHC cis rs41271473 0.526 rs1925720 chr1:228728377 G/C cg10167378 chr1:228756711 NA 0.67 6.77 0.34 5.65e-11 Chronic lymphocytic leukemia; LIHC cis rs7927771 0.542 rs7102205 chr11:47745374 C/T cg20307385 chr11:47447363 PSMC3 0.75 11.24 0.52 3.62e-25 Subjective well-being; LIHC cis rs35883536 0.740 rs4604711 chr1:101089492 A/C cg14515779 chr1:101123966 NA -0.68 -13.21 -0.58 1.81e-32 Monocyte count; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs10791097 0.694 rs7940027 chr11:130745591 A/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6442522 0.678 rs13085575 chr3:15499330 C/T cg16303742 chr3:15540471 COLQ 0.44 7.54 0.38 4.14e-13 Uric acid levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04837231 chr1:7885239 PER3 -0.43 -6.83 -0.35 3.9e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06679563 chr19:33622563 WDR88 -0.42 -6.85 -0.35 3.5e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs6598955 1.000 rs10902728 chr1:26598281 T/C cg04990556 chr1:26633338 UBXN11 0.76 12.92 0.57 2.3e-31 Obesity-related traits; LIHC cis rs9513627 1.000 rs7321269 chr13:100126271 C/T cg25919922 chr13:100150906 NA -0.77 -6.94 -0.35 2.01e-11 Obesity-related traits; LIHC cis rs2404602 0.647 rs11637096 chr15:76931102 T/C cg23625390 chr15:77176239 SCAPER -0.53 -8.71 -0.43 1.28e-16 Blood metabolite levels; LIHC cis rs6831352 0.918 rs1042365 chr4:100045500 G/T cg12011299 chr4:100065546 ADH4 -0.59 -10.18 -0.48 1.95e-21 Alcohol dependence; LIHC cis rs600806 0.778 rs2039694 chr1:109991700 A/G cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.61 -0.38 2.77e-13 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg03517284 chr6:25882590 NA 0.58 7.81 0.39 6.88e-14 Blood metabolite levels; LIHC cis rs10540 1.000 rs12418639 chr11:473300 A/C cg03576123 chr11:487126 PTDSS2 0.87 7.44 0.37 8e-13 Body mass index; LIHC cis rs12497850 0.931 rs7626445 chr3:49114544 C/T cg07636037 chr3:49044803 WDR6 0.93 17.12 0.68 6.92e-48 Parkinson's disease; LIHC cis rs7264396 0.561 rs2064725 chr20:34569142 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.42 -6.52 -0.33 2.5e-10 Total cholesterol levels; LIHC trans rs800082 0.690 rs6440260 chr3:144289214 C/A cg24215973 chr2:240111563 HDAC4 -0.57 -8.76 -0.43 8.89e-17 Smoking behavior; LIHC cis rs3824867 0.920 rs7111873 chr11:47469439 A/G cg20307385 chr11:47447363 PSMC3 0.58 7.74 0.39 1.12e-13 Mean corpuscular hemoglobin; LIHC cis rs1707322 0.686 rs2230659 chr1:46078884 C/T cg06784218 chr1:46089804 CCDC17 -0.42 -7.72 -0.39 1.3e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs16912285 0.688 rs1899540 chr11:24339992 A/G ch.11.24196551F chr11:24239977 NA 0.71 8.42 0.41 1.04e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg19318889 chr4:1322082 MAEA 0.47 6.69 0.34 8.94e-11 Obesity-related traits; LIHC cis rs8180040 0.966 rs11707895 chr3:47574937 G/A cg27129171 chr3:47204927 SETD2 -0.54 -8.65 -0.42 2.07e-16 Colorectal cancer; LIHC cis rs778371 0.630 rs13007579 chr2:233725364 G/A cg08000102 chr2:233561755 GIGYF2 -0.77 -9.42 -0.45 6.9e-19 Schizophrenia; LIHC cis rs903552 1.000 rs12908310 chr15:102003635 A/G cg19295451 chr15:102010161 PCSK6 -0.44 -6.17 -0.32 1.97e-9 Diabetic kidney disease; LIHC cis rs6089829 0.925 rs3746748 chr20:61667526 C/T cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16693872 chr5:176882643 PRR7 -0.4 -6.44 -0.33 4.02e-10 Pancreatic cancer; LIHC cis rs6430585 0.528 rs309158 chr2:136680534 A/G cg15123519 chr2:136567270 LCT -0.32 -5.72 -0.3 2.29e-8 Corneal structure; LIHC cis rs2153535 0.580 rs1855769 chr6:8473095 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.1 0.55 2.7e-28 Motion sickness; LIHC cis rs2286503 0.809 rs4719716 chr7:22861369 G/A cg11367502 chr7:22862612 TOMM7 0.45 7.51 0.38 5.08e-13 Fibrinogen; LIHC trans rs7927370 0.510 rs11559578 chr11:54994975 C/A cg15704280 chr7:45808275 SEPT13 0.58 7.15 0.36 5.28e-12 Systemic lupus erythematosus; LIHC cis rs651907 0.514 rs34301719 chr3:101417993 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -5.98 -0.31 5.7e-9 Colorectal cancer; LIHC cis rs7208859 0.573 rs11654035 chr17:29136426 T/C cg13385521 chr17:29058706 SUZ12P 0.84 8.25 0.41 3.5e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs246600 0.543 rs246607 chr5:142513686 C/T cg04118306 chr8:24772350 NEFM 0.36 6.05 0.31 3.82e-9 Coronary artery disease; LIHC cis rs55665837 0.583 rs78843135 chr11:14411254 T/G cg19336497 chr11:14380999 RRAS2 -0.54 -10.14 -0.48 2.68e-21 Vitamin D levels; LIHC cis rs6558530 0.666 rs6558526 chr8:1702572 A/G cg24391279 chr8:1708526 NA -0.35 -5.85 -0.3 1.14e-8 Systolic blood pressure; LIHC cis rs9910055 0.529 rs575798 chr17:42181796 A/C cg19774624 chr17:42201019 HDAC5 0.48 5.78 0.3 1.64e-8 Total body bone mineral density; LIHC cis rs9517320 0.534 rs912330 chr13:99131294 C/T cg07423050 chr13:99094983 FARP1 -0.45 -7.67 -0.38 1.8e-13 Longevity; LIHC cis rs4819052 1.000 rs13052356 chr21:46663588 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.71 9.47 0.46 4.69e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs763121 0.744 rs5757140 chr22:38957013 T/C cg06022373 chr22:39101656 GTPBP1 0.68 11.53 0.53 3.23e-26 Menopause (age at onset); LIHC cis rs875971 1.000 rs11974219 chr7:65647410 C/T cg18876405 chr7:65276391 NA -0.38 -6.88 -0.35 2.82e-11 Aortic root size; LIHC cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg09222892 chr1:25734099 RHCE -0.45 -8.22 -0.41 4.25e-15 Erythrocyte sedimentation rate; LIHC cis rs898097 0.812 rs56405605 chr17:80843663 T/C cg15664640 chr17:80829946 TBCD -0.78 -12.74 -0.57 1.11e-30 Breast cancer; LIHC cis rs4979906 1.000 rs11002241 chr10:79445327 C/T cg07817648 chr10:79422355 NA -0.3 -6.16 -0.32 2.09e-9 Mortality in heart failure; LIHC cis rs1008375 0.898 rs7670500 chr4:17586957 A/G cg02297831 chr4:17616191 MED28 0.48 7.33 0.37 1.68e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9303401 0.659 rs12600349 chr17:57054245 A/G cg02118635 chr17:56770003 RAD51C;TEX14 -0.94 -12.61 -0.56 3.44e-30 Cognitive test performance; LIHC cis rs2180341 1.000 rs2038378 chr6:127590400 C/T cg24812749 chr6:127587940 RNF146 1.06 15.64 0.65 5.62e-42 Breast cancer; LIHC cis rs2576037 0.583 rs2156049 chr18:44455717 G/A cg19077165 chr18:44547161 KATNAL2 -0.47 -7.09 -0.36 7.75e-12 Personality dimensions; LIHC cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg10802521 chr3:52805072 NEK4 -0.38 -6.04 -0.31 4.13e-9 Bipolar disorder; LIHC cis rs1385374 0.858 rs11059923 chr12:129293057 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.75 0.39 1.09e-13 Systemic lupus erythematosus; LIHC cis rs11655198 1 rs11655198 chr17:38026169 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.82 0.3 1.33e-8 Asthma; LIHC cis rs2404602 0.684 rs28895952 chr15:76856776 A/G cg03037974 chr15:76606532 NA -0.61 -10.3 -0.49 7.81e-22 Blood metabolite levels; LIHC cis rs8064299 0.536 rs2290038 chr17:72786611 G/T cg25054828 chr17:72772726 NAT9;TMEM104 -0.71 -12.16 -0.55 1.62e-28 Monocyte count; LIHC cis rs2412488 0.927 rs6554105 chr4:54290677 A/C cg22241045 chr4:54363911 LNX1 -0.43 -6.96 -0.35 1.7e-11 DNA methylation (variation); LIHC cis rs13191362 1.000 rs35103567 chr6:163183400 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.85 6.68 0.34 9.85e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg07424592 chr7:64974309 NA 0.74 8.6 0.42 2.91e-16 Diabetic kidney disease; LIHC trans rs7246657 0.823 rs4802236 chr19:37919246 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs2710642 0.779 rs360807 chr2:62926859 C/T cg17519650 chr2:63277830 OTX1 -0.54 -8.26 -0.41 3.2e-15 LDL cholesterol levels;LDL cholesterol; LIHC cis rs763121 0.853 rs5757204 chr22:39046700 A/C cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg05185784 chr16:90016020 DEF8 -0.44 -5.71 -0.3 2.4e-8 Skin colour saturation; LIHC cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg25072359 chr17:41440525 NA 0.38 6.0 0.31 5.01e-9 Menopause (age at onset); LIHC cis rs3806843 0.966 rs7710380 chr5:140156264 T/C cg26395211 chr5:140044315 WDR55 -0.42 -6.32 -0.32 8.31e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs780096 0.565 rs13022659 chr2:27743630 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.19 -0.32 1.7e-9 Total body bone mineral density; LIHC cis rs8064299 0.560 rs11077763 chr17:72786029 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.73 12.91 0.57 2.58e-31 Monocyte count; LIHC trans rs11098499 0.954 rs11098525 chr4:120390152 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.79 0.47 3.98e-20 Corneal astigmatism; LIHC cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg05368731 chr17:41323189 NBR1 0.72 12.47 0.56 1.08e-29 Menopause (age at onset); LIHC cis rs2075371 0.933 rs2544182 chr7:133949793 C/T cg11752832 chr7:134001865 SLC35B4 0.52 8.09 0.4 1.04e-14 Mean platelet volume; LIHC cis rs9486715 0.867 rs9372106 chr6:96875058 T/C cg06623918 chr6:96969491 KIAA0776 0.84 14.53 0.62 1.36e-37 Headache; LIHC cis rs9394841 0.692 rs9349202 chr6:41805581 A/C cg08135965 chr6:41755394 TOMM6 0.45 5.94 0.31 6.83e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs11673344 0.504 rs1667377 chr19:37491868 G/A cg27390819 chr19:37464633 NA -0.47 -6.15 -0.32 2.22e-9 Obesity-related traits; LIHC cis rs7395581 0.879 rs3758673 chr11:47278917 C/T cg25783544 chr11:47291846 MADD 0.45 6.66 0.34 1.06e-10 HDL cholesterol; LIHC cis rs11148252 0.669 rs61958050 chr13:52994427 A/C cg00495681 chr13:53174319 NA 0.38 5.94 0.31 6.89e-9 Lewy body disease; LIHC cis rs6674176 0.593 rs6675620 chr1:44417630 C/T cg12908607 chr1:44402522 ARTN -0.47 -8.03 -0.4 1.64e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs34779708 0.931 rs7923217 chr10:35309589 A/G cg03585969 chr10:35415529 CREM 0.78 11.66 0.53 1.08e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg27432699 chr2:27873401 GPN1 -0.49 -7.07 -0.36 8.55e-12 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23821755 chr1:173684675 KLHL20 0.45 6.24 0.32 1.27e-9 Pancreatic cancer; LIHC cis rs12477438 0.798 rs12468419 chr2:99579680 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.51 -0.38 5.04e-13 Chronic sinus infection; LIHC trans rs57221529 0.709 rs4957056 chr5:570105 T/C cg25482853 chr8:67687455 SGK3 0.65 6.37 0.33 6.28e-10 Lung disease severity in cystic fibrosis; LIHC cis rs12586317 0.547 rs2254990 chr14:35465565 T/C cg05294307 chr14:35346193 BAZ1A -0.5 -7.43 -0.37 8.87e-13 Psoriasis; LIHC cis rs881375 0.715 rs10818482 chr9:123648085 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.4 -5.88 -0.3 9.73e-9 Rheumatoid arthritis; LIHC cis rs6461049 0.646 rs3778970 chr7:2143208 C/A cg21782813 chr7:2030301 MAD1L1 0.38 6.52 0.33 2.48e-10 Schizophrenia; LIHC cis rs9457247 1.000 rs2757047 chr6:167374489 C/T cg23791538 chr6:167370224 RNASET2 0.69 11.78 0.54 4.16e-27 Crohn's disease; LIHC cis rs17666538 0.585 rs4448252 chr8:615597 A/G cg07234876 chr8:600039 NA 0.89 7.01 0.35 1.24e-11 IgG glycosylation; LIHC cis rs11190604 1.000 rs11190572 chr10:102232879 A/G cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9640161 0.750 rs73170185 chr7:150030191 C/A cg10018233 chr7:150070692 REPIN1 0.52 8.01 0.4 1.77e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs1023500 0.551 rs133371 chr22:42465574 G/A cg15557168 chr22:42548783 NA -0.42 -6.69 -0.34 8.95e-11 Schizophrenia; LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg10755058 chr3:40428713 ENTPD3 0.4 6.94 0.35 2.02e-11 Renal cell carcinoma; LIHC cis rs10540 1.000 rs12421457 chr11:505780 T/C cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.22e-11 Body mass index; LIHC trans rs3808502 0.527 rs2736374 chr8:11113828 A/G cg05423712 chr8:605100 NA -0.47 -6.28 -0.32 1.02e-9 Neuroticism; LIHC cis rs11098499 0.661 rs10015965 chr4:120268237 A/G cg09307838 chr4:120376055 NA 0.63 9.89 0.47 1.86e-20 Corneal astigmatism; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15916349 chr3:171758196 FNDC3B 0.44 6.15 0.32 2.2e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11396746 chr16:1877632 FAHD1;HAGH -0.46 -6.3 -0.32 9.21e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3749237 0.595 rs4855864 chr3:49521974 C/T cg06212747 chr3:49208901 KLHDC8B 0.43 5.75 0.3 1.97e-8 Resting heart rate; LIHC cis rs8017423 0.967 rs11159956 chr14:90715890 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -14.92 -0.63 3.92e-39 Mortality in heart failure; LIHC trans rs7336933 0.866 rs4941411 chr13:42471498 T/C cg13659026 chr2:85788631 GGCX -0.76 -6.2 -0.32 1.63e-9 Calcium levels; LIHC cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg24209194 chr3:40518798 ZNF619 0.45 6.41 0.33 4.83e-10 Renal cell carcinoma; LIHC cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg03806693 chr22:41940476 POLR3H -0.96 -10.33 -0.49 6.16e-22 Vitiligo; LIHC cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg05590025 chr7:65112418 INTS4L2 0.61 6.74 0.34 6.72e-11 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05052194 chr1:2160249 SKI 0.53 7.37 0.37 1.28e-12 Lung function (FEV1/FVC); LIHC cis rs5753618 0.539 rs8135344 chr22:31671932 G/T cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs11690935 0.632 rs6433323 chr2:172873060 A/G cg13550731 chr2:172543902 DYNC1I2 -0.64 -11.25 -0.52 3.33e-25 Schizophrenia; LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg26338869 chr17:61819248 STRADA 0.6 8.58 0.42 3.31e-16 Prudent dietary pattern; LIHC cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg27170947 chr2:26402098 FAM59B 0.67 8.31 0.41 2.32e-15 Gut microbiome composition (summer); LIHC cis rs250677 0.687 rs36048 chr5:148441713 G/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.48 -0.38 6.18e-13 Breast cancer; LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg27432699 chr2:27873401 GPN1 -0.54 -7.94 -0.39 2.93e-14 Total body bone mineral density; LIHC cis rs910316 1.000 rs2098297 chr14:75619118 G/T cg08847533 chr14:75593920 NEK9 -0.89 -20.26 -0.74 1.6e-60 Height; LIHC cis rs3020736 0.500 rs7364293 chr22:42506370 C/T cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.26 -0.32 1.15e-9 Autism spectrum disorder or schizophrenia; LIHC trans rs801193 0.935 rs2286683 chr7:66129843 G/A cg26939375 chr7:64535504 NA -0.43 -6.8 -0.35 4.57e-11 Aortic root size; LIHC cis rs11229555 0.645 rs34530191 chr11:58200854 A/G cg15696309 chr11:58395628 NA -0.65 -7.67 -0.38 1.76e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs77633900 0.614 rs2170998 chr15:77007159 C/T cg21673338 chr15:77095150 SCAPER 0.45 7.14 0.36 5.56e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs10463316 0.823 rs7700342 chr5:150776323 C/T cg03212797 chr5:150827313 SLC36A1 -0.47 -7.26 -0.37 2.61e-12 Metabolite levels (Pyroglutamine); LIHC trans rs1005277 0.579 rs1780137 chr10:38501475 C/G cg17830980 chr10:43048298 ZNF37B -0.52 -10.15 -0.48 2.43e-21 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg00166722 chr3:10149974 C3orf24 0.52 6.02 0.31 4.54e-9 Alzheimer's disease; LIHC cis rs2075371 0.965 rs2544216 chr7:133987902 G/A cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03169527 chr3:11888582 C3orf31 0.49 7.26 0.37 2.7e-12 Cognitive function; LIHC cis rs72781680 0.898 rs17763224 chr2:24213776 T/C cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs4654899 0.758 rs2320826 chr1:21392096 A/C cg08539965 chr1:21396338 EIF4G3 0.33 5.83 0.3 1.27e-8 Superior frontal gyrus grey matter volume; LIHC cis rs801193 0.569 rs3846973 chr7:66120035 T/C cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs17095355 1.000 rs13377046 chr10:111729228 T/A cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.93 -0.31 7.5e-9 Biliary atresia; LIHC cis rs425277 0.628 rs3128340 chr1:2047496 C/G cg04315214 chr1:2043799 PRKCZ 0.43 6.61 0.34 1.47e-10 Height; LIHC cis rs907683 0.559 rs4674394 chr2:220289870 C/T cg15015639 chr2:220282977 DES -0.36 -8.65 -0.42 2.09e-16 Resting heart rate; LIHC cis rs651907 0.557 rs17347644 chr3:101547733 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.63 9.86 0.47 2.39e-20 Colorectal cancer; LIHC cis rs2273156 1.000 rs12880928 chr14:35475678 A/G cg16230307 chr14:35515116 FAM177A1 -0.41 -6.05 -0.31 3.88e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs11671005 0.735 rs11084543 chr19:58932701 T/C cg25952890 chr19:58913133 NA 0.67 7.2 0.36 3.89e-12 Mean platelet volume; LIHC cis rs1580019 0.587 rs9638880 chr7:32552401 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.15 26.68 0.82 1.39e-85 Cognitive ability; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08023809 chr12:53645616 MFSD5 0.49 6.93 0.35 2.1e-11 Lung function (FEV1/FVC); LIHC cis rs12477438 0.765 rs2309520 chr2:99570477 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.51 8.27 0.41 3.05e-15 Chronic sinus infection; LIHC cis rs908922 0.676 rs4845780 chr1:152488846 T/G cg23254163 chr1:152506842 NA 0.23 6.08 0.31 3.14e-9 Hair morphology; LIHC cis rs28530618 0.515 rs6579027 chr20:31239025 G/T cg13636640 chr20:31349939 DNMT3B -0.42 -5.89 -0.3 9.06e-9 Birth weight; LIHC cis rs801193 0.569 rs35070132 chr7:66238083 C/T cg18252515 chr7:66147081 NA -0.48 -7.1 -0.36 7.38e-12 Aortic root size; LIHC cis rs1005277 0.579 rs1740737 chr10:38499365 G/T cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.75 -0.3 1.94e-8 Extrinsic epigenetic age acceleration; LIHC cis rs2463822 0.925 rs74692811 chr11:62156572 G/A cg06239285 chr11:62104954 ASRGL1 -0.92 -6.89 -0.35 2.69e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg02034447 chr16:89574710 SPG7 0.47 7.12 0.36 6.54e-12 Multiple myeloma (IgH translocation); LIHC cis rs2732480 0.557 rs923397 chr12:48720392 G/A cg21466736 chr12:48725269 NA -0.73 -11.46 -0.53 6.2e-26 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs801193 0.569 rs2659907 chr7:66164032 G/A cg18252515 chr7:66147081 NA -0.47 -6.89 -0.35 2.76e-11 Aortic root size; LIHC cis rs2180341 0.960 rs9401952 chr6:127677027 A/C cg24812749 chr6:127587940 RNF146 1.04 15.17 0.63 4.22e-40 Breast cancer; LIHC cis rs7044106 0.615 rs10818470 chr9:123359204 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.71 10.93 0.51 4.9e-24 Hip circumference adjusted for BMI; LIHC cis rs10242455 0.557 rs73403272 chr7:99134208 T/G cg18809830 chr7:99032528 PTCD1 -0.81 -6.46 -0.33 3.52e-10 Blood metabolite levels; LIHC cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg10862848 chr6:42927986 GNMT -0.25 -6.11 -0.31 2.65e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg26752003 chr8:145688521 CYHR1 0.52 8.27 0.41 3.01e-15 Age at first birth; LIHC cis rs700651 0.821 rs700690 chr2:198727626 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Intracranial aneurysm; LIHC cis rs17376456 0.825 rs12716453 chr5:93271697 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs6461049 0.734 rs1558465 chr7:2151398 G/C cg04267008 chr7:1944627 MAD1L1 -0.47 -7.22 -0.36 3.39e-12 Schizophrenia; LIHC cis rs3096299 0.935 rs3102387 chr16:89432276 A/C cg01788221 chr16:89496183 ANKRD11 -0.38 -5.79 -0.3 1.56e-8 Multiple myeloma (IgH translocation); LIHC cis rs2153535 0.580 rs1414344 chr6:8471365 C/A cg07606381 chr6:8435919 SLC35B3 0.8 12.07 0.55 3.41e-28 Motion sickness; LIHC cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg13395646 chr4:1353034 KIAA1530 -0.5 -8.33 -0.41 1.94e-15 Obesity-related traits; LIHC cis rs1278769 0.786 rs7998551 chr13:113540649 G/T cg00823993 chr13:113535758 ATP11A 0.59 7.25 0.37 2.76e-12 Interstitial lung disease; LIHC trans rs61931739 0.534 rs10844816 chr12:34248533 C/A cg26384229 chr12:38710491 ALG10B 0.58 7.45 0.37 7.89e-13 Morning vs. evening chronotype; LIHC cis rs2075371 0.933 rs432336 chr7:133949064 A/G cg20476274 chr7:133979776 SLC35B4 0.74 12.81 0.57 6.14e-31 Mean platelet volume; LIHC cis rs2576037 0.544 rs629097 chr18:44378097 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.92 -0.31 7.7e-9 Personality dimensions; LIHC cis rs2243480 0.901 rs778687 chr7:65835819 G/A cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs892961 0.932 rs67719929 chr17:75412605 G/A cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg11987759 chr7:65425863 GUSB -0.38 -6.03 -0.31 4.21e-9 Aortic root size; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg01171360 chr6:293285 DUSP22 -0.5 -7.59 -0.38 3.01e-13 Menopause (age at onset); LIHC cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg09222892 chr1:25734099 RHCE -0.45 -7.96 -0.4 2.6e-14 Erythrocyte sedimentation rate; LIHC cis rs16944613 0.510 rs7165429 chr15:91151881 C/T cg26821196 chr15:91095069 CRTC3 0.34 6.27 0.32 1.08e-9 Colorectal cancer; LIHC cis rs12477438 0.520 rs11692699 chr2:99730657 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.88 15.82 0.65 1.09e-42 Chronic sinus infection; LIHC cis rs6456156 0.586 rs12528689 chr6:167461746 A/G cg12798992 chr6:167411361 FGFR1OP 0.42 6.57 0.33 1.87e-10 Primary biliary cholangitis; LIHC cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg14004847 chr7:1930337 MAD1L1 -0.49 -6.93 -0.35 2.13e-11 Bipolar disorder and schizophrenia; LIHC cis rs16912285 0.688 rs7124856 chr11:24324926 C/T ch.11.24196551F chr11:24239977 NA 0.8 10.63 0.5 5.36e-23 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs7149337 0.836 rs35345236 chr14:51671817 T/C cg23942311 chr14:51606299 NA 0.34 6.69 0.34 9.17e-11 Cancer; LIHC cis rs7552404 1.000 rs1498315 chr1:76159225 G/A cg03433033 chr1:76189801 ACADM 0.66 9.39 0.45 8.81e-19 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg06651054 chr15:83680015 C15orf40 -0.42 -6.34 -0.32 7.33e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7927771 0.965 rs35184771 chr11:47475189 G/T cg18512352 chr11:47633146 NA -0.25 -5.9 -0.3 8.85e-9 Subjective well-being; LIHC cis rs782590 0.818 rs2627765 chr2:55883317 G/T cg18811423 chr2:55921094 PNPT1 0.82 12.59 0.56 4.04e-30 Metabolic syndrome; LIHC cis rs6942756 0.531 rs2896415 chr7:128904523 G/A cg02491457 chr7:128862824 NA 0.58 9.59 0.46 1.9e-19 White matter hyperintensity burden; LIHC cis rs1143633 0.530 rs2723163 chr2:113694339 A/G cg12858261 chr2:113808755 IL1F8 0.34 5.86 0.3 1.1e-8 Allergic disease (asthma, hay fever or eczema); LIHC cis rs425277 0.538 rs169037 chr1:2095582 G/T cg24578937 chr1:2090814 PRKCZ 0.33 6.19 0.32 1.7e-9 Height; LIHC cis rs2816062 0.813 rs2745314 chr1:18902851 T/A cg18795169 chr1:18902165 NA -0.79 -17.2 -0.68 3.35e-48 Urate levels in lean individuals; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.68e-17 Prudent dietary pattern; LIHC cis rs858239 0.932 rs858272 chr7:23276785 A/G cg00469287 chr7:23338798 C7orf30 0.41 5.75 0.3 1.97e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs727563 0.580 rs202626 chr22:41847190 C/A cg17554472 chr22:41940697 POLR3H 0.55 6.33 0.32 7.79e-10 Crohn's disease;Inflammatory bowel disease; LIHC cis rs892961 1.000 rs11077909 chr17:75403480 T/C cg05865280 chr17:75406074 SEPT9 0.58 15.36 0.64 7.48e-41 Airflow obstruction; LIHC cis rs8038465 0.662 rs57771618 chr15:73967578 T/C cg15420318 chr15:73925796 NPTN 0.37 5.85 0.3 1.13e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.46 -0.37 7.01e-13 Lymphocyte counts; LIHC cis rs138880 0.542 rs9616393 chr22:50314809 A/G cg09182678 chr22:50328711 NA 0.7 8.3 0.41 2.39e-15 Schizophrenia; LIHC cis rs10540 1.000 rs35068485 chr11:466032 A/T cg03352830 chr11:487213 PTDSS2 0.67 6.05 0.31 3.71e-9 Body mass index; LIHC cis rs2632516 1.000 rs2526378 chr17:56404349 A/G cg12560992 chr17:57184187 TRIM37 0.43 5.83 0.3 1.3e-8 Alzheimer's disease;Alzheimer's disease in APOE e4- carriers;Monocyte count; LIHC cis rs1728785 1.000 rs698712 chr16:68561879 G/A cg02972257 chr16:68554789 NA -0.52 -6.0 -0.31 4.96e-9 Ulcerative colitis; LIHC cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs2346177 0.542 rs13024414 chr2:46687062 G/A cg02822958 chr2:46747628 ATP6V1E2 0.47 6.92 0.35 2.3e-11 HDL cholesterol; LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg15586393 chr4:1244086 CTBP1;C4orf42 -0.41 -5.71 -0.3 2.44e-8 Longevity; LIHC cis rs7208859 0.623 rs28556733 chr17:29083945 T/G cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67478160 0.643 rs4900594 chr14:104251006 C/T cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.11 -0.36 6.77e-12 Schizophrenia; LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg09417038 chr21:47716443 C21orf57 0.46 7.14 0.36 5.48e-12 Testicular germ cell tumor; LIHC cis rs7296418 0.961 rs4275659 chr12:123447928 C/T cg00376283 chr12:123451042 ABCB9 -0.78 -14.15 -0.61 4.04e-36 Platelet count; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg09126038 chr10:8056860 NA 0.38 6.51 0.33 2.74e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs7197653 0.748 rs2279538 chr16:68397106 C/G cg05110241 chr16:68378359 PRMT7 -0.85 -9.58 -0.46 2.07e-19 Magnesium levels; LIHC cis rs7212938 0.509 rs3893044 chr17:38103016 C/T cg17467752 chr17:38218738 THRA -0.42 -6.94 -0.35 1.98e-11 Asthma and hay fever; LIHC cis rs782590 0.774 rs782637 chr2:55894247 T/C cg18811423 chr2:55921094 PNPT1 0.88 14.01 0.6 1.47e-35 Metabolic syndrome; LIHC trans rs7613875 0.600 rs7061 chr3:50114515 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.55 -0.33 2.12e-10 Body mass index; LIHC cis rs10464366 0.544 rs1525799 chr7:39153131 C/G cg10621924 chr7:39171070 POU6F2 -0.41 -6.35 -0.32 6.84e-10 IgG glycosylation; LIHC cis rs752010 0.631 rs4660549 chr1:42088102 A/G cg06885757 chr1:42089581 HIVEP3 0.49 7.08 0.36 8.08e-12 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg13409248 chr3:40428643 ENTPD3 0.4 6.52 0.33 2.59e-10 Renal cell carcinoma; LIHC cis rs7116495 0.609 rs10898812 chr11:71698801 G/A cg10381502 chr11:71823885 C11orf51 -1.0 -8.24 -0.41 3.84e-15 Severe influenza A (H1N1) infection; LIHC cis rs7647973 0.566 rs57630346 chr3:49086215 T/C cg20833759 chr3:49053208 WDR6;DALRD3 0.55 6.58 0.34 1.79e-10 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08496016 chr9:99181722 ZNF367 0.41 6.26 0.32 1.17e-9 Pancreatic cancer; LIHC cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg23978390 chr7:1156363 C7orf50 0.52 7.58 0.38 3.19e-13 Longevity;Endometriosis; LIHC cis rs76533333 0.564 rs7331609 chr13:113420339 C/T cg08557188 chr13:113420371 ATP11A -0.77 -5.83 -0.3 1.32e-8 Red cell distribution width; LIHC cis rs4891159 0.790 rs8085133 chr18:74144083 A/C cg24786174 chr18:74118243 ZNF516 -0.78 -14.99 -0.63 2.15e-39 Longevity; LIHC cis rs838721 0.574 rs11676156 chr2:234259001 G/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.41 5.88 0.3 9.84e-9 Total body bone mineral density; LIHC cis rs1215050 0.874 rs2167893 chr4:99048464 A/T cg05340658 chr4:99064831 C4orf37 0.42 6.13 0.31 2.37e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs738322 0.870 rs2277844 chr22:38577515 G/A cg25457927 chr22:38595422 NA 0.38 9.51 0.46 3.45e-19 Cutaneous nevi; LIHC cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg27170947 chr2:26402098 FAM59B -0.65 -8.21 -0.41 4.67e-15 Gut microbiome composition (summer); LIHC cis rs4423214 1.000 rs12806844 chr11:71170770 G/A cg24826892 chr11:71159390 DHCR7 0.48 6.16 0.32 1.99e-9 Vitamin D levels; LIHC cis rs2991971 0.810 rs6657237 chr1:45920108 A/T cg05343316 chr1:45956843 TESK2 0.45 6.66 0.34 1.13e-10 High light scatter reticulocyte count; LIHC cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg00750074 chr16:89608354 SPG7 -0.53 -8.42 -0.41 1.06e-15 Multiple myeloma (IgH translocation); LIHC cis rs5769765 0.819 rs9616377 chr22:50310880 T/C cg02269571 chr22:50332266 NA -0.75 -9.95 -0.47 1.14e-20 Schizophrenia; LIHC cis rs7927592 0.763 rs7120876 chr11:68261398 C/G cg20283391 chr11:68216788 NA -0.37 -5.94 -0.31 7.17e-9 Total body bone mineral density; LIHC cis rs7927771 0.793 rs12803525 chr11:47413475 G/A cg20135002 chr11:47629003 NA -0.52 -8.73 -0.43 1.15e-16 Subjective well-being; LIHC cis rs12497850 0.764 rs6784111 chr3:49178846 T/C cg16497277 chr3:49208875 KLHDC8B -0.47 -5.73 -0.3 2.2e-8 Parkinson's disease; LIHC cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg25894440 chr7:65020034 NA -0.54 -6.13 -0.31 2.46e-9 Diabetic kidney disease; LIHC cis rs7582720 1.000 rs72936353 chr2:204070956 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.76 6.13 0.31 2.36e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg06634786 chr22:41940651 POLR3H -0.74 -8.06 -0.4 1.31e-14 Vitiligo; LIHC cis rs7917772 0.503 rs11191321 chr10:104293412 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs1814175 0.817 rs11040651 chr11:49938395 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs651907 0.535 rs34263427 chr3:101507805 A/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.81 -0.3 1.4e-8 Colorectal cancer; LIHC cis rs1355223 0.902 rs11605785 chr11:34751387 G/A cg11058730 chr11:34937778 PDHX;APIP -0.47 -6.55 -0.33 2.09e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs151997 0.630 rs26064 chr5:50217806 T/C cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg01448562 chr3:133502909 NA -0.43 -6.77 -0.34 5.62e-11 Iron status biomarkers; LIHC cis rs929354 0.772 rs6969244 chr7:157004012 A/G cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.94e-9 Body mass index; LIHC cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.9 9.37 0.45 1e-18 Platelet count; LIHC cis rs9549367 0.713 rs2476328 chr13:113829350 C/T cg00898013 chr13:113819073 PROZ 0.42 7.23 0.36 3.23e-12 Platelet distribution width; LIHC cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg18357526 chr6:26021779 HIST1H4A -0.52 -6.97 -0.35 1.61e-11 Blood metabolite levels; LIHC cis rs875971 1.000 rs6957199 chr7:65978519 T/C cg11764359 chr7:65958608 NA 0.91 16.91 0.67 4.67e-47 Aortic root size; LIHC cis rs12291225 0.883 rs1864658 chr11:14256444 C/T cg19336497 chr11:14380999 RRAS2 0.47 8.66 0.42 1.89e-16 Sense of smell; LIHC cis rs10916814 0.546 rs1890006 chr1:20898841 G/T cg24502330 chr1:20914028 CDA -0.3 -6.7 -0.34 8.63e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs67311347 1.000 rs9829800 chr3:40443927 T/C cg00656387 chr3:40428638 ENTPD3 0.4 6.56 0.33 2.01e-10 Renal cell carcinoma; LIHC cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg22105103 chr4:187893119 NA 0.35 8.88 0.43 3.78e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs9814567 1.000 rs12637751 chr3:134266124 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs904251 0.734 rs2797790 chr6:37447075 A/G cg01843034 chr6:37503916 NA 0.4 6.56 0.33 2e-10 Cognitive performance; LIHC cis rs10779751 0.770 rs2275527 chr1:11190646 A/G cg08854313 chr1:11322531 MTOR 0.69 9.29 0.45 1.81e-18 Body mass index; LIHC cis rs1865760 0.929 rs1816546 chr6:25938252 C/T cg12310025 chr6:25882481 NA -0.42 -6.34 -0.32 7.32e-10 Height; LIHC cis rs9393692 0.645 rs766407 chr6:26319534 T/C cg13736514 chr6:26305472 NA -0.4 -6.23 -0.32 1.37e-9 Educational attainment; LIHC cis rs7772486 0.754 rs10872580 chr6:146140281 C/T cg23711669 chr6:146136114 FBXO30 -0.75 -13.93 -0.6 2.98e-35 Lobe attachment (rater-scored or self-reported); LIHC cis rs28655083 0.828 rs11640648 chr16:77122494 T/C cg01753188 chr16:77233325 SYCE1L;MON1B 0.46 6.93 0.35 2.16e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg08280861 chr8:58055591 NA 0.51 6.29 0.32 9.56e-10 Developmental language disorder (linguistic errors); LIHC cis rs929354 0.772 rs2301914 chr7:157000176 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.89 0.3 9.45e-9 Body mass index; LIHC cis rs7927592 0.731 rs2840367 chr11:68302101 G/A cg01657329 chr11:68192670 LRP5 0.5 7.38 0.37 1.23e-12 Total body bone mineral density; LIHC cis rs10911251 0.546 rs2027084 chr1:183110801 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.58 0.5 8.3300000000000006e-23 Colorectal cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03904586 chr7:559740 PDGFA 0.42 6.08 0.31 3.19e-9 Lung function (FEV1/FVC); LIHC cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg05025164 chr4:1340916 KIAA1530 0.52 7.64 0.38 2.23e-13 Longevity; LIHC cis rs13108904 0.901 rs12509700 chr4:1296321 A/G cg19318889 chr4:1322082 MAEA 0.47 7.72 0.39 1.33e-13 Obesity-related traits; LIHC cis rs2033908 0.588 rs1899068 chr11:12872156 A/T cg25843174 chr11:12811716 TEAD1 0.32 7.52 0.38 5e-13 Sitting height ratio; LIHC cis rs2243480 0.522 rs1638736 chr7:66092308 A/T cg05590025 chr7:65112418 INTS4L2 -0.58 -5.89 -0.3 9.23e-9 Diabetic kidney disease; LIHC trans rs7246657 0.943 rs28373708 chr19:37976659 C/T cg10208301 chr11:6592745 DNHD1 0.45 6.45 0.33 3.73e-10 Coronary artery calcification; LIHC trans rs11098499 0.954 rs12508504 chr4:120410607 A/C cg25214090 chr10:38739885 LOC399744 0.59 9.63 0.46 1.44e-19 Corneal astigmatism; LIHC cis rs11146838 1 rs11146838 chr10:39149977 A/T cg25427524 chr10:38739819 LOC399744 -0.69 -12.76 -0.57 9.53e-31 Breast cancer; LIHC cis rs10838687 0.736 rs16938581 chr11:47271039 G/A cg25783544 chr11:47291846 MADD 0.46 5.84 0.3 1.2e-8 Proinsulin levels; LIHC cis rs6449957 0.832 rs11742365 chr5:67470244 C/G cg23036683 chr5:67512108 NA 0.47 6.6 0.34 1.53e-10 Cleft lip with or without cleft palate; LIHC cis rs9303401 0.659 rs16943326 chr17:57050365 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.28 0.58 9.81e-33 Cognitive test performance; LIHC cis rs116095464 0.558 rs73031482 chr5:227594 G/A cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs10411936 0.962 rs2607278 chr19:16568197 C/T cg10248733 chr19:16607483 C19orf44;CALR3 -0.43 -5.8 -0.3 1.5e-8 White blood cell count;Multiple sclerosis; LIHC cis rs875971 0.862 rs10950033 chr7:65739673 A/G cg18252515 chr7:66147081 NA 0.45 6.37 0.33 6.18e-10 Aortic root size; LIHC cis rs3018712 0.532 rs28551086 chr11:68400739 G/A cg16797656 chr11:68205561 LRP5 0.48 6.03 0.31 4.31e-9 Total body bone mineral density; LIHC cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg13047869 chr3:10149882 C3orf24 -0.49 -6.01 -0.31 4.67e-9 Alzheimer's disease; LIHC cis rs67981189 0.593 rs2877714 chr14:71568215 G/T cg15816911 chr14:71606274 NA 0.43 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs7618501 0.932 rs4855850 chr3:49761571 G/A cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC cis rs941873 0.868 rs7898 chr10:81114959 C/T cg11057378 chr10:81107060 PPIF 0.37 6.01 0.31 4.75e-9 Height; LIHC cis rs1577917 0.958 rs36053156 chr6:86575509 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.24 -0.52 3.79e-25 Response to antipsychotic treatment; LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.53 -7.5 -0.38 5.62e-13 Lymphocyte counts; LIHC cis rs4561483 0.583 rs1019813 chr16:11940829 C/T cg08843971 chr16:11963173 GSPT1 0.37 7.04 0.36 1.04e-11 Testicular germ cell tumor; LIHC cis rs898097 0.567 rs8076119 chr17:80910061 A/G cg15664640 chr17:80829946 TBCD 0.46 7.54 0.38 4.31e-13 Breast cancer; LIHC cis rs35306767 0.903 rs11253460 chr10:887382 C/G cg26597838 chr10:835615 NA 1.2 14.83 0.63 8.74e-39 Eosinophil percentage of granulocytes; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg09948192 chr4:7069943 GRPEL1 0.43 6.04 0.31 4e-9 Alopecia areata; LIHC cis rs7208859 0.623 rs216446 chr17:28933718 T/G cg13385521 chr17:29058706 SUZ12P 0.67 6.57 0.33 1.88e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs57221529 0.713 rs56328416 chr5:591138 G/A cg09021430 chr5:549028 NA -0.43 -8.53 -0.42 4.8e-16 Lung disease severity in cystic fibrosis; LIHC cis rs2250402 0.510 rs6492926 chr15:40325829 T/G cg20255370 chr15:40268687 EIF2AK4 -0.5 -5.74 -0.3 2.13e-8 Corneal curvature; LIHC cis rs317689 0.718 rs315122 chr12:69771073 G/T cg22834771 chr12:69754056 YEATS4 -0.39 -5.91 -0.3 8.46e-9 Response to diuretic therapy; LIHC cis rs875971 0.928 rs6970357 chr7:65968878 T/C cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.54e-9 Aortic root size; LIHC cis rs892961 0.867 rs1079354 chr17:75415713 C/T cg01320579 chr17:75405842 SEPT9 0.55 7.33 0.37 1.71e-12 Airflow obstruction; LIHC cis rs600806 0.815 rs10858094 chr1:109950858 T/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.07 -0.31 3.42e-9 Intelligence (multi-trait analysis); LIHC cis rs2050392 0.965 rs2480279 chr10:30700032 C/T cg25182066 chr10:30743637 MAP3K8 -0.44 -7.06 -0.36 9.24e-12 Inflammatory bowel disease; LIHC cis rs9486719 0.843 rs2499797 chr6:96848669 C/T cg06623918 chr6:96969491 KIAA0776 0.61 5.72 0.3 2.36e-8 Migraine;Coronary artery disease; LIHC cis rs929354 1.000 rs929354 chr7:157045557 C/T cg17757837 chr7:157058334 UBE3C -0.71 -11.96 -0.54 8.52e-28 Body mass index; LIHC cis rs5769707 0.967 rs5769698 chr22:49997706 A/G cg07959070 chr22:50026188 C22orf34 -0.32 -8.44 -0.42 8.89e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs62380364 0.565 rs617944 chr5:88057915 T/C cg22951263 chr5:87985283 NA -0.41 -7.09 -0.36 7.72e-12 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.765 rs2838827 chr21:46656146 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.5 6.91 0.35 2.33e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7937682 0.889 rs484013 chr11:111495779 G/A cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs12086130 0.881 rs77603669 chr1:51423779 G/T cg07174182 chr1:51127561 FAF1 -0.72 -7.52 -0.38 4.76e-13 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs4820539 0.966 rs5759600 chr22:23483769 C/A cg14186256 chr22:23484241 RTDR1 0.92 18.77 0.71 1.58e-54 Bone mineral density; LIHC cis rs11673344 0.864 rs703535 chr19:37505740 A/G cg27390819 chr19:37464633 NA -0.52 -6.38 -0.33 5.73e-10 Obesity-related traits; LIHC cis rs9309473 0.950 rs6705977 chr2:73849170 C/G cg20560298 chr2:73613845 ALMS1 -0.53 -6.56 -0.33 1.95e-10 Metabolite levels; LIHC trans rs3780486 0.757 rs10758189 chr9:33125804 A/G cg20290983 chr6:43655470 MRPS18A 1.11 28.78 0.84 2.24e-93 IgG glycosylation; LIHC cis rs4853012 0.838 rs59570457 chr2:74344282 T/C cg19729930 chr2:74357872 NA 0.81 17.77 0.69 1.64e-50 Gestational age at birth (maternal effect); LIHC cis rs35110281 0.744 rs162396 chr21:44947807 T/C cg21573476 chr21:45109991 RRP1B -0.51 -9.33 -0.45 1.35e-18 Mean corpuscular volume; LIHC cis rs1538970 0.962 rs9429075 chr1:45818421 G/A cg24296786 chr1:45957014 TESK2 -0.49 -7.17 -0.36 4.75e-12 Platelet count; LIHC cis rs988712 0.672 rs12419948 chr11:27666984 T/A cg18117895 chr11:27722066 BDNF 0.49 6.85 0.35 3.45e-11 Obesity; LIHC cis rs11711311 1.000 rs12636577 chr3:113497507 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.84 -0.35 3.69e-11 IgG glycosylation; LIHC cis rs4988958 0.565 rs3771154 chr2:103039360 C/T cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma (childhood onset); LIHC cis rs11792861 0.926 rs72607170 chr9:111836941 G/A cg05043794 chr9:111880884 C9orf5 -0.3 -6.94 -0.35 1.97e-11 Menarche (age at onset); LIHC cis rs950776 0.714 rs615470 chr15:78885988 T/C cg06917634 chr15:78832804 PSMA4 -0.59 -8.18 -0.4 5.72e-15 Sudden cardiac arrest; LIHC cis rs881375 0.967 rs1930781 chr9:123687834 G/A cg14580859 chr9:123691850 NA 0.39 6.85 0.35 3.45e-11 Rheumatoid arthritis; LIHC cis rs1018836 0.923 rs2105965 chr8:91537690 T/C cg16814680 chr8:91681699 NA -0.6 -9.74 -0.47 6.21e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs12478296 1.000 rs56323081 chr2:243040807 A/G cg05760424 chr2:242988095 NA -0.5 -6.67 -0.34 1.03e-10 Obesity-related traits; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg07341007 chr3:195489909 MUC4 -0.45 -7.83 -0.39 6.12e-14 Lung disease severity in cystic fibrosis; LIHC cis rs9300255 0.602 rs1616131 chr12:123619838 G/A cg00376283 chr12:123451042 ABCB9 0.58 6.44 0.33 4.09e-10 Neutrophil percentage of white cells; LIHC cis rs933688 1.000 rs2052553 chr5:90729906 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.26 0.68 1.78e-48 Smoking behavior; LIHC trans rs1814175 0.817 rs2866545 chr11:49630824 A/C cg18944383 chr4:111397179 ENPEP 0.25 6.22 0.32 1.43e-9 Height; LIHC cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg09222892 chr1:25734099 RHCE -0.48 -8.9 -0.43 3.41e-17 Erythrocyte sedimentation rate; LIHC cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg05552183 chr6:42928497 GNMT 0.69 10.19 0.48 1.74e-21 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg10299061 chr3:53078990 SFMBT1 -0.4 -6.04 -0.31 3.93e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs875971 1.000 rs6958277 chr7:65979349 A/G cg10756647 chr7:56101905 PSPH 0.44 6.43 0.33 4.28e-10 Aortic root size; LIHC cis rs9611519 0.732 rs1883826 chr22:41703428 G/A cg06634786 chr22:41940651 POLR3H -0.53 -6.26 -0.32 1.17e-9 Neuroticism; LIHC cis rs3020736 0.500 rs6002603 chr22:42492362 C/G cg15557168 chr22:42548783 NA 0.46 7.08 0.36 8.47e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs4237845 0.537 rs59401446 chr12:58259564 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.56 7.89 0.39 4.17e-14 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21313137 chr20:44462302 SNX21 0.66 8.93 0.43 2.66e-17 Lung function (FEV1/FVC); LIHC cis rs782590 0.967 rs35504023 chr2:55806503 C/T cg03859395 chr2:55845619 SMEK2 -0.82 -14.54 -0.62 1.23e-37 Metabolic syndrome; LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.7 11.76 0.54 4.68e-27 Height; LIHC cis rs6754311 0.551 rs9287442 chr2:136522710 A/G cg25344623 chr2:136566232 LCT 0.38 7.29 0.37 2.21e-12 Mosquito bite size; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.48 0.56 1.05e-29 Prudent dietary pattern; LIHC trans rs7618501 1.000 rs2234391 chr3:49842625 A/G cg21582582 chr3:182698605 DCUN1D1 0.54 7.13 0.36 5.97e-12 Intelligence (multi-trait analysis); LIHC trans rs867371 1.000 rs6495643 chr15:82479254 C/G cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.6 -0.34 1.58e-10 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7927771 0.524 rs10838763 chr11:47794802 C/T cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs9303401 0.614 rs66480139 chr17:57101538 G/A cg25039879 chr17:56429692 SUPT4H1 0.76 8.75 0.43 1.02e-16 Cognitive test performance; LIHC cis rs72634258 0.554 rs12061787 chr1:7888730 G/C cg26816564 chr1:7831052 VAMP3 0.66 6.03 0.31 4.31e-9 Inflammatory bowel disease; LIHC cis rs1707322 0.685 rs6690926 chr1:46134978 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1144333 0.850 rs1251274 chr1:76288587 T/C cg03433033 chr1:76189801 ACADM -0.56 -8.49 -0.42 6.24e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.08 0.31 3.13e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1371867 0.775 rs6511 chr8:101252680 T/C cg06636551 chr8:101224915 SPAG1 0.49 9.36 0.45 1.11e-18 Atrioventricular conduction; LIHC cis rs11122272 0.766 rs2790870 chr1:231543823 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.91 -0.51 5.6e-24 Hemoglobin concentration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02998992 chr17:19265610 B9D1 0.44 6.28 0.32 1.03e-9 Lung function (FEV1/FVC); LIHC cis rs7103648 0.966 rs896817 chr11:47394305 A/G cg20307385 chr11:47447363 PSMC3 -0.97 -16.61 -0.67 7.62e-46 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg24642844 chr7:1081250 C7orf50 -0.92 -8.96 -0.44 2.13e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9640161 0.711 rs3800781 chr7:150027324 T/A cg27494647 chr7:150038898 RARRES2 0.32 5.83 0.3 1.26e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs2050392 0.760 rs10826797 chr10:30690376 A/C cg25182066 chr10:30743637 MAP3K8 -0.59 -9.69 -0.46 8.69e-20 Inflammatory bowel disease; LIHC cis rs1046896 0.514 rs9894705 chr17:80823758 A/C cg02398342 chr17:80708632 TBCD;FN3K -0.41 -6.31 -0.32 8.63e-10 Glycated hemoglobin levels; LIHC cis rs853679 0.517 rs1947862 chr6:28105196 C/T cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg12292205 chr6:26970375 C6orf41 0.48 8.48 0.42 6.69e-16 Autism spectrum disorder or schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17024643 chr1:214725274 PTPN14 0.42 6.36 0.33 6.36e-10 Lung function (FEV1/FVC); LIHC cis rs28735056 0.933 rs56181785 chr18:77633629 G/A cg20368463 chr18:77673604 PQLC1 -0.37 -6.44 -0.33 4.15e-10 Schizophrenia; LIHC cis rs2549003 1.000 rs2548997 chr5:131835395 C/T cg21138405 chr5:131827807 IRF1 -0.35 -8.81 -0.43 6.62e-17 Asthma (sex interaction); LIHC cis rs11864453 0.647 rs9932062 chr16:72136055 T/C cg01557791 chr16:72042693 DHODH -0.45 -7.52 -0.38 4.95e-13 Fibrinogen levels; LIHC cis rs7208859 0.623 rs8082537 chr17:29015932 T/C cg13385521 chr17:29058706 SUZ12P 0.71 7.22 0.36 3.31e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2979489 0.891 rs2979504 chr8:30386641 C/T cg26383811 chr8:30366931 RBPMS -0.7 -11.55 -0.53 2.75e-26 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07089834 chr17:79239572 SLC38A10 0.42 6.22 0.32 1.41e-9 Longevity; LIHC cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg27286337 chr10:134555280 INPP5A 0.92 13.04 0.58 7.93e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7208859 0.673 rs11656462 chr17:29160700 G/A cg13385521 chr17:29058706 SUZ12P 0.81 7.99 0.4 2.04e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7208859 0.673 rs9889755 chr17:29234505 A/G cg13385521 chr17:29058706 SUZ12P -0.8 -8.34 -0.41 1.83e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7917772 0.582 rs10883736 chr10:104320029 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.95 0.39 2.81e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6547741 0.752 rs7562863 chr2:27892694 T/A cg27432699 chr2:27873401 GPN1 -0.86 -14.65 -0.62 4.49e-38 Oral cavity cancer; LIHC cis rs708547 0.723 rs35982175 chr4:57841365 C/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.64 11.19 0.52 5.6e-25 Response to bleomycin (chromatid breaks); LIHC cis rs2257205 0.667 rs7207254 chr17:56912572 C/T cg12560992 chr17:57184187 TRIM37 0.6 5.88 0.3 9.65e-9 Pancreatic cancer; LIHC trans rs877282 1.000 rs71491304 chr10:772982 C/T cg22713356 chr15:30763199 NA 1.23 10.89 0.51 6.83e-24 Uric acid levels; LIHC cis rs3749237 0.964 rs1799843 chr3:49849723 G/A cg03060546 chr3:49711283 APEH 0.37 5.9 0.3 8.53e-9 Resting heart rate; LIHC cis rs6964587 0.869 rs6946764 chr7:91539003 A/G cg17063962 chr7:91808500 NA -0.98 -18.67 -0.71 3.85e-54 Breast cancer; LIHC cis rs2108622 0.701 rs118144071 chr19:15979194 A/G cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2455601 0.882 rs11042118 chr11:8928791 T/A cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -6.17 -0.32 1.91e-9 Schizophrenia; LIHC cis rs6754311 0.597 rs6760329 chr2:136544752 A/G cg25344623 chr2:136566232 LCT 0.32 6.13 0.31 2.39e-9 Mosquito bite size; LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg09455208 chr3:40491958 NA -0.38 -7.47 -0.37 6.77e-13 Renal cell carcinoma; LIHC cis rs17401966 0.964 rs34215045 chr1:10361679 G/A cg19773385 chr1:10388646 KIF1B -0.48 -8.25 -0.41 3.5e-15 Hepatocellular carcinoma; LIHC cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg15534755 chr11:117069859 TAGLN 0.4 6.75 0.34 6.43e-11 Blood protein levels; LIHC cis rs10276381 0.786 rs73300665 chr7:28227024 G/A cg23620719 chr7:28220237 JAZF1 0.66 8.15 0.4 7.18e-15 Crohn's disease; LIHC cis rs9916302 0.821 rs1966915 chr17:37425262 A/C cg03013999 chr17:37608204 MED1 0.36 6.03 0.31 4.18e-9 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.913 rs11228276 chr11:68307525 A/G cg20283391 chr11:68216788 NA -0.52 -7.73 -0.39 1.24e-13 Total body bone mineral density; LIHC trans rs800082 1.000 rs9849975 chr3:144294530 A/G cg24215973 chr2:240111563 HDAC4 -0.42 -6.12 -0.31 2.56e-9 Smoking behavior; LIHC cis rs908922 0.676 rs569032 chr1:152508615 C/T cg20991723 chr1:152506922 NA 0.54 9.49 0.46 4.07e-19 Hair morphology; LIHC cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg10295955 chr4:187884368 NA -0.96 -21.95 -0.76 2.89e-67 Lobe attachment (rater-scored or self-reported); LIHC cis rs11792861 0.926 rs72607169 chr9:111832471 A/T cg13535736 chr9:111863775 C9orf5 -0.4 -6.0 -0.31 4.89e-9 Menarche (age at onset); LIHC cis rs11229555 0.645 rs7116007 chr11:58218701 C/T cg15696309 chr11:58395628 NA -0.64 -7.43 -0.37 9.04e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2180341 0.814 rs6919277 chr6:127738050 T/C cg24812749 chr6:127587940 RNF146 0.77 11.72 0.54 6.72e-27 Breast cancer; LIHC cis rs7639513 0.520 rs4684111 chr3:12729485 T/G cg23032965 chr3:12705835 RAF1 0.56 6.08 0.31 3.3e-9 Itch intensity from mosquito bite; LIHC cis rs7412746 0.646 rs10399947 chr1:150861960 G/A cg15448220 chr1:150897856 SETDB1 0.38 6.07 0.31 3.39e-9 Melanoma; LIHC cis rs8180040 0.726 rs4234465 chr3:47026885 C/G cg27129171 chr3:47204927 SETD2 0.52 8.59 0.42 3.05e-16 Colorectal cancer; LIHC cis rs55823223 0.564 rs936396 chr17:73846829 C/G cg19302996 chr17:73780495 UNK -0.54 -6.72 -0.34 7.78e-11 Psoriasis; LIHC cis rs909002 0.886 rs10798880 chr1:32097088 G/T cg13919466 chr1:32135498 COL16A1 -0.31 -6.0 -0.31 4.92e-9 Intelligence (multi-trait analysis); LIHC cis rs965469 0.779 rs2236114 chr20:3296040 A/G cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC trans rs2243480 1.000 rs313807 chr7:65499481 C/T cg10756647 chr7:56101905 PSPH 1.09 13.55 0.59 9.11e-34 Diabetic kidney disease; LIHC cis rs4820294 0.547 rs62236743 chr22:38096053 T/C cg10587741 chr22:38071170 LGALS1 0.68 9.51 0.46 3.59e-19 Fat distribution (HIV); LIHC cis rs9534288 0.664 rs1926447 chr13:46629944 C/T cg15192986 chr13:46630673 CPB2 0.5 7.46 0.37 7.1e-13 Blood protein levels; LIHC cis rs2180341 1.000 rs2180341 chr6:127600630 C/T cg24812749 chr6:127587940 RNF146 1.03 15.42 0.64 4.12e-41 Breast cancer; LIHC cis rs477895 0.941 rs12808002 chr11:64110932 C/T cg04317338 chr11:64019027 PLCB3 0.84 7.6 0.38 2.82e-13 Mean platelet volume; LIHC cis rs2153535 0.580 rs2327051 chr6:8441150 A/G cg07606381 chr6:8435919 SLC35B3 -0.78 -12.06 -0.55 3.85e-28 Motion sickness; LIHC cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg08280861 chr8:58055591 NA 0.54 6.1 0.31 2.9e-9 Developmental language disorder (linguistic errors); LIHC cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg07414643 chr4:187882934 NA 0.23 5.97 0.31 6.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs2274273 0.905 rs8007614 chr14:55586575 A/G cg01864836 chr14:55583639 NA -0.39 -7.45 -0.37 7.89e-13 Protein biomarker; LIHC trans rs12753920 0.683 rs4658128 chr1:92574745 G/A cg15668468 chr10:118892869 VAX1 0.44 6.18 0.32 1.79e-9 Systemic lupus erythematosus; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01110552 chr10:103578627 MGEA5 0.4 6.68 0.34 9.48e-11 Cognitive function; LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg06656553 chr16:89960601 TCF25 -0.46 -5.86 -0.3 1.08e-8 Skin colour saturation; LIHC cis rs6754311 0.773 rs309125 chr2:136643555 C/T cg25344623 chr2:136566232 LCT -0.4 -8.05 -0.4 1.34e-14 Mosquito bite size; LIHC cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg04025307 chr7:1156635 C7orf50 0.67 11.66 0.53 1.1e-26 Longevity;Endometriosis; LIHC cis rs9916302 0.851 rs11868029 chr17:37650304 A/G cg07936489 chr17:37558343 FBXL20 -0.81 -12.96 -0.57 1.63e-31 Glomerular filtration rate (creatinine); LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.21 -0.32 1.57e-9 Total body bone mineral density; LIHC cis rs60871478 1.000 rs62432251 chr7:801855 T/G cg27478167 chr7:817139 HEATR2 -0.42 -5.96 -0.31 6.25e-9 Cerebrospinal P-tau181p levels; LIHC cis rs2749592 0.550 rs4934881 chr10:37914346 A/C cg25427524 chr10:38739819 LOC399744 0.57 10.4 0.49 3.53e-22 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs8064024 0.557 rs7193783 chr16:4949608 A/C cg08329684 chr16:4932620 PPL -0.38 -6.59 -0.34 1.69e-10 Cancer; LIHC cis rs7937890 0.535 rs2575857 chr11:14501296 C/T cg02886208 chr11:14281011 SPON1 -0.44 -6.15 -0.32 2.17e-9 Mitochondrial DNA levels; LIHC cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg18357526 chr6:26021779 HIST1H4A 0.82 10.14 0.48 2.72e-21 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.929 rs1816546 chr6:25938252 C/T cg03264133 chr6:25882463 NA -0.42 -6.26 -0.32 1.18e-9 Height; LIHC cis rs4671458 0.762 rs12464471 chr2:63686428 A/G cg17519650 chr2:63277830 OTX1 -0.55 -6.33 -0.32 7.76e-10 Subjective well-being; LIHC trans rs2243480 0.908 rs55876148 chr7:65379800 G/A cg10756647 chr7:56101905 PSPH 1.1 13.34 0.59 5.59e-33 Diabetic kidney disease; LIHC trans rs4843747 0.749 rs12102841 chr16:88072574 C/G cg26811252 chr16:29126840 RRN3P2 -0.48 -7.87 -0.39 4.69e-14 Menopause (age at onset); LIHC cis rs921968 0.565 rs12612395 chr2:219621642 G/C cg02985541 chr2:219472218 PLCD4 -0.36 -6.36 -0.33 6.34e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs801193 1.000 rs3857688 chr7:66127806 G/A cg26939375 chr7:64535504 NA -0.43 -6.8 -0.35 4.57e-11 Aortic root size; LIHC cis rs1443512 0.812 rs1992563 chr12:54330441 G/T cg12374095 chr12:54320830 NA 0.44 6.36 0.33 6.39e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC trans rs3176789 0.647 rs9971740 chr12:9921527 C/T cg18988856 chr7:99425577 CYP3A43 0.19 6.16 0.32 2.05e-9 Lymphocyte percentage of white cells;Neutrophil percentage of white cells; LIHC cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg22442454 chr1:209979470 IRF6 0.39 5.92 0.3 7.76e-9 Cleft lip with or without cleft palate; LIHC cis rs79976124 0.837 rs11751994 chr6:66644028 A/C cg07460842 chr6:66804631 NA 0.65 6.88 0.35 2.89e-11 Type 2 diabetes; LIHC cis rs473651 0.935 rs35080527 chr2:239351387 T/C cg18131467 chr2:239335373 ASB1 1.1 20.95 0.75 2.8e-63 Multiple system atrophy; LIHC cis rs17253792 0.822 rs77761669 chr14:56034216 G/A cg01858014 chr14:56050164 KTN1 -0.71 -7.56 -0.38 3.63e-13 Putamen volume; LIHC cis rs8017423 0.935 rs11626869 chr14:90788985 A/G cg04374321 chr14:90722782 PSMC1 -0.72 -13.46 -0.59 1.89e-33 Mortality in heart failure; LIHC cis rs1865760 1.000 rs3752421 chr6:25918688 G/A cg03264133 chr6:25882463 NA -0.38 -5.72 -0.3 2.36e-8 Height; LIHC trans rs916888 0.697 rs199516 chr17:44856485 C/T cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs1814175 0.817 rs1621090 chr11:49895868 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs1018836 0.663 rs3950221 chr8:91478108 G/A cg16814680 chr8:91681699 NA -0.4 -6.38 -0.33 5.61e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs2727020 0.729 rs6485965 chr11:49166730 C/T cg18944383 chr4:111397179 ENPEP -0.25 -6.18 -0.32 1.86e-9 Coronary artery disease; LIHC cis rs963731 0.649 rs6544191 chr2:39266384 C/T cg04010122 chr2:39346883 SOS1 -0.75 -6.29 -0.32 9.91e-10 Corticobasal degeneration; LIHC cis rs875971 1.000 rs3735148 chr7:65971009 T/G cg11764359 chr7:65958608 NA 0.91 16.91 0.67 4.58e-47 Aortic root size; LIHC cis rs921968 0.565 rs6436069 chr2:219597185 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01174859 chr7:128379317 CALU -0.44 -6.39 -0.33 5.47e-10 Pancreatic cancer; LIHC cis rs11931598 1.000 rs11931598 chr4:7047102 A/G cg26116260 chr4:7069785 GRPEL1 0.43 6.9 0.35 2.52e-11 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs2976388 0.609 rs2376491 chr8:143790934 G/A cg13446199 chr8:143762866 PSCA -0.2 -5.78 -0.3 1.71e-8 Urinary tract infection frequency; LIHC cis rs10503871 0.594 rs10954994 chr8:30306419 C/A cg26383811 chr8:30366931 RBPMS 0.4 6.9 0.35 2.61e-11 Metabolite levels (X-11787); LIHC cis rs35883536 1.000 rs2065784 chr1:101096056 A/G cg14515779 chr1:101123966 NA 0.64 12.16 0.55 1.65e-28 Monocyte count; LIHC cis rs12188164 0.525 rs1114665 chr5:452247 C/T cg16584290 chr5:462447 EXOC3 0.36 5.71 0.3 2.45e-8 Cystic fibrosis severity; LIHC cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 10.93 0.51 4.65e-24 Platelet count; LIHC trans rs2727020 0.617 rs7102702 chr11:49401125 T/G cg15704280 chr7:45808275 SEPT13 -0.8 -12.69 -0.57 1.65e-30 Coronary artery disease; LIHC cis rs6089584 0.528 rs4925334 chr20:60626769 C/T cg06108461 chr20:60628389 TAF4 -0.65 -8.98 -0.44 1.87e-17 Body mass index; LIHC cis rs875971 0.798 rs57739047 chr7:65972566 A/T cg18876405 chr7:65276391 NA 0.35 6.45 0.33 3.86e-10 Aortic root size; LIHC cis rs7703744 0.639 rs1396609 chr5:118685885 A/G cg04195774 chr5:118677172 TNFAIP8 -0.41 -5.97 -0.31 5.79e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.875 rs1331637 chr6:146337087 T/C cg05347473 chr6:146136440 FBXO30 0.37 5.99 0.31 5.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17152411 1.000 rs733401 chr10:126594158 A/T cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.33e-12 Height; LIHC cis rs9473924 0.542 rs9473954 chr6:50928547 G/A cg14470998 chr6:50812995 TFAP2B 0.86 7.83 0.39 6.39e-14 Body mass index; LIHC trans rs668210 0.793 rs1151514 chr11:65758854 G/A cg17712092 chr4:129076599 LARP1B 0.57 6.17 0.32 1.9e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.55 7.29 0.37 2.15e-12 Osteoporosis; LIHC cis rs7959452 0.557 rs899224 chr12:69784774 A/G cg22834771 chr12:69754056 YEATS4 -0.52 -9.23 -0.45 2.82e-18 Blood protein levels; LIHC cis rs11758351 0.660 rs16891443 chr6:26221937 A/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs5769707 0.521 rs739244 chr22:50060158 A/G cg01652190 chr22:50026171 C22orf34 -0.29 -6.32 -0.32 8.06e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2455601 0.638 rs11042148 chr11:9008674 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.47 -6.69 -0.34 9.25e-11 Schizophrenia; LIHC cis rs12824058 0.798 rs7968728 chr12:130804696 T/A cg24229701 chr12:130821962 PIWIL1 0.43 6.14 0.32 2.26e-9 Menopause (age at onset); LIHC cis rs2251381 0.722 rs2251278 chr21:30529234 A/G cg08807101 chr21:30365312 RNF160 0.76 10.02 0.48 6.72e-21 Selective IgA deficiency; LIHC cis rs7116495 0.609 rs577435 chr11:71794681 C/T cg26138937 chr11:71823887 C11orf51 -1.32 -10.43 -0.49 2.71e-22 Severe influenza A (H1N1) infection; LIHC cis rs16828019 0.852 rs34979067 chr1:41543084 G/A cg03962019 chr1:41807865 NA 0.5 7.32 0.37 1.83e-12 Intelligence (multi-trait analysis); LIHC cis rs249954 0.512 rs249867 chr16:23668568 G/A cg01460202 chr16:23706506 ERN2 0.36 5.97 0.31 5.9e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2839186 0.903 rs61182475 chr21:47707050 T/A cg12016809 chr21:47604291 C21orf56 0.41 6.09 0.31 3e-9 Testicular germ cell tumor; LIHC cis rs10927875 1.000 rs10927875 chr1:16299312 A/G cg21385522 chr1:16154831 NA 0.87 11.42 0.53 8.52e-26 Dilated cardiomyopathy; LIHC cis rs12971120 0.685 rs34780792 chr18:72173278 G/A cg26446133 chr18:72167187 CNDP2 -0.78 -14.05 -0.6 1.03e-35 Refractive error; LIHC cis rs67478160 0.584 rs2295148 chr14:104195610 T/C cg01849466 chr14:104193079 ZFYVE21 -0.56 -9.97 -0.47 1.04e-20 Schizophrenia; LIHC cis rs2832191 0.692 rs2245517 chr21:30357968 C/T cg24692254 chr21:30365293 RNF160 0.85 15.07 0.63 1.06e-39 Dental caries; LIHC cis rs864643 1.000 rs1768267 chr3:39560436 T/A cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs11711311 0.911 rs9817327 chr3:113478500 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.23 0.45 2.97e-18 IgG glycosylation; LIHC cis rs1997103 0.954 rs7811098 chr7:55413012 A/G cg17469321 chr7:55412551 NA 0.49 7.19 0.36 3.98e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9457247 0.663 rs12526548 chr6:167431147 C/T cg07741184 chr6:167504864 NA 0.25 5.96 0.31 6.39e-9 Crohn's disease; LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.58 0.38 3.25e-13 Height; LIHC cis rs4908760 0.731 rs12075458 chr1:8758794 C/A cg20416874 chr1:8611966 RERE -0.63 -11.97 -0.54 8.48e-28 Vitiligo; LIHC cis rs4523957 0.928 rs7213232 chr17:2165340 A/G cg16513277 chr17:2031491 SMG6 -0.46 -7.11 -0.36 6.73e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9596863 0.898 rs9568919 chr13:54352229 T/G ch.13.53330881F chr13:54432880 NA 0.45 6.04 0.31 3.93e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg08392591 chr16:89556376 ANKRD11 0.55 8.78 0.43 7.98e-17 Multiple myeloma (IgH translocation); LIHC cis rs57502260 0.915 rs75202638 chr11:68210421 C/T cg20283391 chr11:68216788 NA -0.47 -5.8 -0.3 1.55e-8 Total body bone mineral density (age 45-60); LIHC cis rs67460515 0.563 rs7618924 chr3:160855599 A/G cg17135325 chr3:160939158 NMD3 0.54 7.76 0.39 1.01e-13 Parkinson's disease; LIHC cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9296092 0.538 rs80012910 chr6:33519542 G/A cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs9940464 0.933 rs13333697 chr16:83367411 C/T cg13016115 chr14:23388406 RBM23 0.38 6.15 0.32 2.21e-9 Malaria; LIHC cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg06212747 chr3:49208901 KLHDC8B -0.52 -6.57 -0.33 1.91e-10 Menarche (age at onset); LIHC trans rs2727020 0.554 rs7111711 chr11:49557880 G/A cg15704280 chr7:45808275 SEPT13 -0.8 -12.0 -0.54 6.26e-28 Coronary artery disease; LIHC cis rs7395581 0.918 rs3816725 chr11:47305669 T/G cg25783544 chr11:47291846 MADD 0.44 6.33 0.32 7.7e-10 HDL cholesterol; LIHC cis rs6426558 0.621 rs7521639 chr1:227223736 T/C cg10327440 chr1:227177885 CDC42BPA 0.59 9.51 0.46 3.56e-19 Neutrophil percentage of white cells; LIHC cis rs6450176 1.000 rs3776706 chr5:53304933 T/G ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.66 -0.62 4.37e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2050392 0.517 rs619864 chr10:30750950 A/G cg25182066 chr10:30743637 MAP3K8 0.64 10.44 0.49 2.5e-22 Inflammatory bowel disease; LIHC cis rs12908161 1.000 rs60957376 chr15:85280792 T/G cg17507749 chr15:85114479 UBE2QP1 0.63 7.3 0.37 2e-12 Schizophrenia; LIHC cis rs2073300 0.609 rs56334525 chr20:23365812 A/G cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2463822 1.000 rs72921501 chr11:62115622 A/T cg06239285 chr11:62104954 ASRGL1 -0.96 -6.97 -0.35 1.65e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs17292804 0.506 rs71417868 chr14:104046592 A/T cg24130564 chr14:104152367 KLC1 -0.54 -9.03 -0.44 1.29e-17 Autism spectrum disorder or schizophrenia; LIHC cis rs10832963 0.847 rs4237722 chr11:18639363 T/C cg09201001 chr11:18656081 SPTY2D1 0.94 16.78 0.67 1.6e-46 Breast cancer; LIHC trans rs71007656 1 rs71007656 chr10:37970845 CGGCTG/C cg27523141 chr10:43048294 ZNF37B 0.37 6.36 0.33 6.61e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7091068 0.507 rs913046 chr10:95408484 A/C cg20715218 chr10:95462985 C10orf4 0.55 8.9 0.43 3.26e-17 Urinary tract infection frequency; LIHC cis rs2760061 0.598 rs590657 chr1:228117581 A/C cg02753203 chr1:228287806 NA -0.49 -7.61 -0.38 2.71e-13 Diastolic blood pressure; LIHC cis rs4332037 0.586 rs62442944 chr7:2015047 T/G cg23422044 chr7:1970798 MAD1L1 -0.64 -7.19 -0.36 4.17e-12 Bipolar disorder; LIHC cis rs4713118 0.513 rs149945 chr6:28002853 T/C cg16479474 chr6:28041457 NA 0.38 6.24 0.32 1.29e-9 Parkinson's disease; LIHC cis rs12893668 0.703 rs4906335 chr14:104021141 C/A cg24130564 chr14:104152367 KLC1 -0.56 -9.02 -0.44 1.42e-17 Reticulocyte count; LIHC cis rs10870270 1.000 rs11146324 chr10:133767445 A/C cg26149184 chr10:133730230 NA 0.47 7.49 0.38 5.75e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs208520 1.000 rs72882086 chr6:66976671 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 6.93 0.35 2.06e-11 Exhaled nitric oxide output; LIHC cis rs7312933 0.703 rs10492388 chr12:42608001 T/C cg01256987 chr12:42539512 GXYLT1 -0.42 -7.04 -0.36 1.09e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01714823 chr3:195269708 PPP1R2 0.53 6.2 0.32 1.62e-9 Hepatitis; LIHC trans rs13113518 0.812 rs4864996 chr4:56319088 A/C cg15358633 chr12:38710606 ALG10B 0.44 6.34 0.32 7.47e-10 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07560662 chr1:117113232 CD58 0.47 6.48 0.33 3.14e-10 Lung function (FEV1/FVC); LIHC cis rs7659604 0.540 rs4833769 chr4:122672970 A/C cg19671926 chr4:122722719 EXOSC9 -0.45 -6.66 -0.34 1.07e-10 Type 2 diabetes; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs9916302 0.904 rs8079303 chr17:37530755 G/C cg03013999 chr17:37608204 MED1 -0.36 -5.95 -0.31 6.7e-9 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg00280220 chr17:61926910 NA 0.42 6.74 0.34 6.67e-11 Prudent dietary pattern; LIHC cis rs6793245 0.810 rs9843500 chr3:38588095 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.51 -7.48 -0.37 6.46e-13 QT interval; LIHC cis rs9549367 0.789 rs9549699 chr13:113878263 T/A cg18105134 chr13:113819100 PROZ -0.67 -11.62 -0.53 1.57e-26 Platelet distribution width; LIHC cis rs10791323 0.569 rs1119852 chr11:133743022 C/A cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.58e-9 Childhood ear infection; LIHC cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg12463550 chr7:65579703 CRCP -0.65 -6.61 -0.34 1.52e-10 Diabetic kidney disease; LIHC cis rs4888262 0.526 rs6564142 chr16:74590047 T/C cg01733217 chr16:74700730 RFWD3 0.79 15.12 0.63 6.73e-40 Testicular germ cell tumor; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg22786486 chr22:20073528 MIR1306;DGCR8 0.42 6.08 0.31 3.3e-9 Lung function (FEV1); LIHC cis rs10744422 1.000 rs1532835 chr12:123330665 G/A cg25930673 chr12:123319894 HIP1R -0.92 -12.17 -0.55 1.51e-28 Schizophrenia; LIHC cis rs6942756 0.876 rs822040 chr7:129065922 C/G cg02491457 chr7:128862824 NA 0.59 9.1 0.44 7.4e-18 White matter hyperintensity burden; LIHC trans rs916888 0.779 rs430685 chr17:44859148 T/C cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11608355 0.545 rs4766475 chr12:109908373 G/A cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs910316 0.763 rs12588981 chr14:75460561 A/G cg11812906 chr14:75593930 NEK9 0.74 13.69 0.59 2.63e-34 Height; LIHC cis rs3204270 1.000 rs3204270 chr17:79682051 C/T cg18367735 chr17:79674897 NA 0.72 6.82 0.35 4.2e-11 Dental caries; LIHC cis rs2439831 0.681 rs540031 chr15:43608855 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.78 11.87 0.54 1.92e-27 Lung cancer in ever smokers; LIHC cis rs1419980 0.586 rs10845548 chr12:7777657 T/A cg25828445 chr12:7781288 NA -0.42 -6.53 -0.33 2.4e-10 HDL cholesterol levels; LIHC cis rs2067615 0.560 rs12298717 chr12:107099883 C/T cg15890332 chr12:107067104 RFX4 -0.26 -6.24 -0.32 1.26e-9 Heart rate; LIHC cis rs2268241 0.938 rs9978166 chr21:34770516 A/G cg14850771 chr21:34775459 IFNGR2 0.89 13.34 0.59 5.48e-33 Obesity-related traits; LIHC cis rs2404602 0.692 rs2137307 chr15:77149020 T/A cg03037974 chr15:76606532 NA 0.74 14.58 0.62 8.64e-38 Blood metabolite levels; LIHC cis rs546131 0.928 rs553789 chr11:34827579 G/A cg06937548 chr11:34938143 PDHX;APIP 0.58 7.88 0.39 4.27e-14 Lung disease severity in cystic fibrosis; LIHC trans rs7120489 0.655 rs7940867 chr11:12445264 T/C cg08537300 chr5:179058959 NA 0.58 6.31 0.32 8.59e-10 Mortality in heart failure; LIHC cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg00149659 chr3:10157352 C3orf10 0.61 6.71 0.34 7.86e-11 Alzheimer's disease; LIHC cis rs28595532 1.000 rs11938970 chr4:119660152 A/G cg14228332 chr4:119757509 SEC24D 0.67 6.45 0.33 3.8e-10 Cannabis dependence symptom count; LIHC trans rs2727020 0.514 rs4980444 chr11:49550764 T/A cg03929089 chr4:120376271 NA -0.88 -16.75 -0.67 2e-46 Coronary artery disease; LIHC cis rs11671005 0.735 rs12981649 chr19:58930043 G/C cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs1355223 0.902 rs4465347 chr11:34727333 C/T cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.43 -0.33 4.36e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs67311347 0.866 rs3214006 chr3:40352134 C/T cg00656387 chr3:40428638 ENTPD3 0.39 6.03 0.31 4.26e-9 Renal cell carcinoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21565415 chr11:618993 MUPCDH 0.39 6.36 0.33 6.34e-10 Cognitive function; LIHC cis rs9921222 0.509 rs3743883 chr16:404750 T/C cg00101154 chr16:420108 MRPL28 -0.42 -6.4 -0.33 5.18e-10 Bone mineral density (spine);Bone mineral density; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10932289 chr17:55038442 COIL -0.48 -6.83 -0.35 3.94e-11 Pancreatic cancer; LIHC cis rs9379850 0.730 rs9393738 chr6:26620658 G/A cg12826209 chr6:26865740 GUSBL1 0.55 5.71 0.3 2.44e-8 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg22974920 chr21:40686053 BRWD1 -0.4 -5.85 -0.3 1.13e-8 Cognitive function; LIHC cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 9.61 0.46 1.6e-19 Platelet count; LIHC cis rs57502260 0.573 rs12291008 chr11:68389072 T/C cg01657329 chr11:68192670 LRP5 -0.46 -5.82 -0.3 1.35e-8 Total body bone mineral density (age 45-60); LIHC trans rs8073060 0.586 rs4796100 chr17:33997657 G/T cg19694781 chr19:47549865 TMEM160 1.24 13.36 0.59 4.6e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs13191362 0.810 rs13209784 chr6:162961274 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.7 6.0 0.31 5.09e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs796364 1.000 rs281771 chr2:200812202 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -8.1 -0.4 9.94e-15 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07907917 chr19:40949191 SERTAD3 0.41 6.19 0.32 1.71e-9 Pancreatic cancer; LIHC cis rs7688540 0.723 rs17521834 chr4:225449 C/T cg12746427 chr4:53362 ZNF718;ZNF595 -0.26 -5.82 -0.3 1.38e-8 Facial morphology (factor 6, height of vermillion lower lip); LIHC cis rs9733 0.596 rs72702536 chr1:150662574 C/T cg13175981 chr1:150552382 MCL1 -0.44 -6.05 -0.31 3.7e-9 Tonsillectomy; LIHC cis rs8180040 1.000 rs807936 chr3:47322496 C/T cg02527881 chr3:46936655 PTH1R -0.3 -5.89 -0.3 9.21e-9 Colorectal cancer; LIHC cis rs6089584 0.508 rs6061988 chr20:60626300 C/T cg23262073 chr20:60523788 NA -0.28 -5.78 -0.3 1.73e-8 Body mass index; LIHC cis rs921968 0.542 rs588182 chr2:219412335 C/A cg02985541 chr2:219472218 PLCD4 0.42 6.91 0.35 2.38e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs62458065 1.000 rs10250808 chr7:32466153 T/C cg06627557 chr7:32535165 LSM5;AVL9 -0.65 -7.37 -0.37 1.3e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs56104184 1.000 rs56104184 chr19:49370310 C/T cg21252483 chr19:49399788 TULP2 -0.78 -9.73 -0.47 6.48e-20 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs921968 0.608 rs832817 chr2:219358603 C/T cg18887096 chr2:219472410 PLCD4 0.36 6.39 0.33 5.46e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs763121 0.962 rs2071887 chr22:38879010 A/T cg06022373 chr22:39101656 GTPBP1 0.47 7.85 0.39 5.27e-14 Menopause (age at onset); LIHC cis rs2235642 0.717 rs2236269 chr16:1652614 T/A cg09025071 chr16:1593152 IFT140;TMEM204 0.29 5.77 0.3 1.82e-8 Coronary artery disease; LIHC cis rs72627509 0.904 rs17081935 chr4:57823476 C/T cg26694713 chr4:57773883 REST 0.69 9.42 0.45 6.73e-19 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7296418 0.961 rs11613937 chr12:123520071 C/T cg05973401 chr12:123451056 ABCB9 0.51 8.11 0.4 9.26e-15 Platelet count; LIHC cis rs2153535 0.584 rs9502721 chr6:8541379 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.23 0.41 4.04e-15 Motion sickness; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg06873352 chr17:61820015 STRADA 0.73 12.8 0.57 6.46e-31 Prudent dietary pattern; LIHC cis rs1728785 0.688 rs698718 chr16:68560185 A/G cg02972257 chr16:68554789 NA -0.53 -6.24 -0.32 1.32e-9 Ulcerative colitis; LIHC cis rs2404602 0.647 rs7181506 chr15:76935677 G/T cg03037974 chr15:76606532 NA 0.54 8.81 0.43 6.58e-17 Blood metabolite levels; LIHC cis rs4713118 0.662 rs149900 chr6:28014597 C/T cg16479474 chr6:28041457 NA 0.47 7.15 0.36 5.3e-12 Parkinson's disease; LIHC cis rs11958404 0.615 rs7703242 chr5:157447920 T/C cg05962755 chr5:157440814 NA 0.59 7.83 0.39 6.15e-14 IgG glycosylation; LIHC cis rs11031096 0.678 rs1442727 chr11:4188188 G/T cg18678763 chr11:4115507 RRM1 0.39 5.79 0.3 1.56e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC cis rs3857067 0.806 rs4693001 chr4:95115097 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs6429082 0.818 rs291344 chr1:235663860 C/G cg26050004 chr1:235667680 B3GALNT2 -0.47 -7.1 -0.36 7.19e-12 Adiposity; LIHC cis rs6089584 0.888 rs6089623 chr20:60615759 A/G cg23262073 chr20:60523788 NA -0.29 -5.93 -0.31 7.44e-9 Body mass index; LIHC trans rs6598955 0.671 rs17163751 chr1:26568698 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.81 -9.1 -0.44 7.57e-18 Obesity-related traits; LIHC cis rs7769051 0.711 rs7770081 chr6:133089569 G/T cg07930552 chr6:133119739 C6orf192 0.67 6.64 0.34 1.26e-10 Type 2 diabetes nephropathy; LIHC cis rs743757 1.000 rs2236979 chr3:50486895 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.4 0.37 1.07e-12 Diastolic blood pressure; LIHC cis rs10080237 0.564 rs2490232 chr6:80814802 C/T cg08355045 chr6:80787529 NA -0.34 -7.08 -0.36 8.14e-12 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals; LIHC cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.07 -0.44 9.45e-18 Bipolar disorder; LIHC cis rs1552244 0.882 rs28366039 chr3:10028988 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -9.8 -0.47 3.86e-20 Alzheimer's disease; LIHC cis rs4788570 0.566 rs16972808 chr16:71478717 A/G cg06353428 chr16:71660113 MARVELD3 -0.99 -9.14 -0.44 5.79e-18 Intelligence (multi-trait analysis); LIHC cis rs10463316 0.894 rs869198 chr5:150745893 G/T cg03212797 chr5:150827313 SLC36A1 0.45 6.91 0.35 2.36e-11 Metabolite levels (Pyroglutamine); LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg03524611 chr8:27631853 ESCO2 -0.58 -6.12 -0.31 2.56e-9 Obesity-related traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03031660 chr17:73257791 MRPS7;GGA3 -0.46 -6.08 -0.31 3.21e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs8078723 0.966 rs57968500 chr17:38145828 A/G cg17467752 chr17:38218738 THRA 0.74 13.3 0.58 8.41e-33 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg11890956 chr21:40555474 PSMG1 -0.55 -9.11 -0.44 7.01e-18 Cognitive function; LIHC cis rs1008375 0.932 rs6449315 chr4:17590219 A/G cg02297831 chr4:17616191 MED28 0.42 5.89 0.3 9.11e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7107174 1.000 rs10793295 chr11:77996521 C/G cg02023728 chr11:77925099 USP35 -0.46 -8.73 -0.43 1.14e-16 Testicular germ cell tumor; LIHC cis rs6430585 0.528 rs309142 chr2:136715324 T/C cg07169764 chr2:136633963 MCM6 0.98 15.49 0.64 2.24e-41 Corneal structure; LIHC cis rs9303401 0.614 rs17175663 chr17:57108437 G/C cg25039879 chr17:56429692 SUPT4H1 0.75 8.46 0.42 7.96e-16 Cognitive test performance; LIHC cis rs11673344 0.704 rs1667384 chr19:37416754 C/T cg27390819 chr19:37464633 NA -0.5 -6.01 -0.31 4.69e-9 Obesity-related traits; LIHC cis rs11123170 0.640 rs2863240 chr2:113970116 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.46 -5.79 -0.3 1.56e-8 Renal function-related traits (BUN); LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg18000306 chr6:288505 NA 0.34 6.37 0.33 6.22e-10 Menopause (age at onset); LIHC cis rs17376456 0.569 rs6895356 chr5:93060781 A/G cg25358565 chr5:93447407 FAM172A 0.75 7.44 0.37 8.47e-13 Diabetic retinopathy; LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.05 -0.31 3.78e-9 Total body bone mineral density; LIHC cis rs4253772 0.591 rs6519994 chr22:46656805 A/G cg09491104 chr22:46646882 C22orf40 0.69 8.07 0.4 1.19e-14 LDL cholesterol;Cholesterol, total; LIHC trans rs12478296 1.000 rs55767645 chr2:242999350 G/A cg01596870 chr19:55963115 NA -0.61 -7.07 -0.36 8.6e-12 Obesity-related traits; LIHC cis rs11671005 0.735 rs11668789 chr19:58928309 C/T cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs623264 0.920 rs676382 chr19:5469107 C/T cg03088458 chr19:5478473 NA -0.36 -6.23 -0.32 1.34e-9 Interleukin-2 receptor antagonist levels; LIHC cis rs6545883 0.929 rs10173974 chr2:61748900 C/G cg14146966 chr2:61757674 XPO1 0.48 8.52 0.42 5.13e-16 Tuberculosis; LIHC cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg00204748 chr12:29376779 FAR2 0.43 8.01 0.4 1.83e-14 QT interval; LIHC cis rs2806561 0.929 rs9426694 chr1:23539742 T/C cg19743168 chr1:23544995 NA 0.42 7.8 0.39 7.64e-14 Height; LIHC cis rs208520 0.634 rs3909071 chr6:66836947 T/C cg07460842 chr6:66804631 NA -0.79 -8.65 -0.42 1.96e-16 Exhaled nitric oxide output; LIHC cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg20684491 chr1:25596433 NA 0.29 5.89 0.3 9.04e-9 Erythrocyte sedimentation rate; LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg04267008 chr7:1944627 MAD1L1 -0.69 -11.31 -0.52 2.11e-25 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.966 rs878659 chr3:47500662 G/A cg27129171 chr3:47204927 SETD2 0.58 9.91 0.47 1.63e-20 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03060925 chr19:41256330 C19orf54;SNRPA 0.45 6.09 0.31 2.96e-9 Pancreatic cancer; LIHC cis rs1552244 0.572 rs68121641 chr3:10165845 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs4563143 0.514 rs73029079 chr19:29294903 A/G cg14983838 chr19:29218262 NA 0.44 6.49 0.33 3.06e-10 Methadone dose in opioid dependence; LIHC cis rs9790314 1.000 rs6765269 chr3:160948542 T/C cg03342759 chr3:160939853 NMD3 -0.74 -8.97 -0.44 1.96e-17 Morning vs. evening chronotype; LIHC cis rs12048904 0.595 rs2295280 chr1:101342497 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 7.19 0.36 4.18e-12 Multiple sclerosis; LIHC cis rs4803468 1.000 rs1473248 chr19:41923314 C/T cg14132834 chr19:41945861 ATP5SL 0.44 6.49 0.33 3.04e-10 Height; LIHC cis rs12477438 0.798 rs17708218 chr2:99696284 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.88 -0.65 6.03e-43 Chronic sinus infection; LIHC cis rs4728302 0.838 rs10264922 chr7:133598975 A/G cg10665199 chr7:133106180 EXOC4 0.38 6.63 0.34 1.28e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7903847 0.620 rs3737194 chr10:99130127 A/G cg20016023 chr10:99160130 RRP12 -0.37 -5.94 -0.31 6.94e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs6693295 0.793 rs2787962 chr1:246240267 A/G cg22732515 chr19:44031385 ETHE1 0.42 6.05 0.31 3.86e-9 Migraine - clinic-based;Migraine with aura; LIHC cis rs7618501 0.602 rs2245365 chr3:50097319 C/A cg24110177 chr3:50126178 RBM5 0.5 7.99 0.4 2.03e-14 Intelligence (multi-trait analysis); LIHC cis rs9858542 0.953 rs9837027 chr3:49597013 C/T cg03060546 chr3:49711283 APEH -0.47 -6.35 -0.32 6.85e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4665809 0.941 rs41285975 chr2:26351144 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg05527609 chr1:210001259 C1orf107 0.43 6.36 0.33 6.51e-10 Cleft lip with or without cleft palate; LIHC cis rs10193935 0.901 rs222471 chr2:42638057 C/T cg27598129 chr2:42591480 NA 0.74 11.48 0.53 5.2e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs4789452 0.595 rs7359497 chr17:75352173 C/T cg05865280 chr17:75406074 SEPT9 0.34 6.97 0.35 1.63e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs9470366 0.545 rs4713999 chr6:36633069 A/G cg08179530 chr6:36648295 CDKN1A -0.6 -8.95 -0.44 2.33e-17 QRS duration; LIHC cis rs8060686 0.545 rs75229939 chr16:68164949 G/A cg09835421 chr16:68378352 PRMT7 -0.54 -6.13 -0.31 2.41e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs35110281 0.774 rs2838327 chr21:45018566 A/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.22 0.32 1.42e-9 Mean corpuscular volume; LIHC cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg24642844 chr7:1081250 C7orf50 -0.63 -6.38 -0.33 5.61e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7089973 0.604 rs11196937 chr10:116589500 G/C cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4819052 0.851 rs2838833 chr21:46665160 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.39 0.37 1.13e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2242116 0.900 rs4683300 chr3:46934292 C/A cg27129171 chr3:47204927 SETD2 0.48 7.67 0.38 1.79e-13 Birth weight; LIHC cis rs921968 0.643 rs596076 chr2:219451015 T/G cg17980119 chr2:219472607 PLCD4 0.34 5.87 0.3 1.06e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg18538332 chr22:24372958 LOC391322 -0.69 -10.39 -0.49 3.57e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4969178 0.965 rs8071889 chr17:76398101 A/G cg20026190 chr17:76395443 PGS1 0.45 7.11 0.36 6.72e-12 HDL cholesterol levels; LIHC cis rs7264396 0.635 rs6058363 chr20:34505054 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.54 -0.5 1.12e-22 Total cholesterol levels; LIHC cis rs1707322 1.000 rs9803784 chr1:46401907 T/C cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.77e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs3744061 0.520 rs4322697 chr17:74648642 C/T cg13533061 chr17:74712429 JMJD6 -0.29 -5.76 -0.3 1.89e-8 Retinal arteriolar caliber; LIHC trans rs11098499 0.739 rs2203039 chr4:120132347 T/C cg25214090 chr10:38739885 LOC399744 -0.38 -6.26 -0.32 1.12e-9 Corneal astigmatism; LIHC cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg14393609 chr7:65229607 NA 0.44 6.56 0.33 2.04e-10 Calcium levels; LIHC cis rs7208859 0.673 rs9899349 chr17:29200122 C/T cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11628318 0.713 rs4900543 chr14:103029024 T/C cg23461800 chr14:103021989 NA -0.5 -7.11 -0.36 6.66e-12 Platelet count; LIHC cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg11644478 chr21:40555479 PSMG1 0.86 11.01 0.51 2.45e-24 Cognitive function; LIHC cis rs12188164 0.543 rs890972 chr5:462465 C/A cg07599136 chr5:415885 AHRR 0.39 6.75 0.34 6.32e-11 Cystic fibrosis severity; LIHC cis rs7487075 0.578 rs10880967 chr12:46812023 T/C cg23829395 chr12:46796953 NA 0.35 6.26 0.32 1.16e-9 Itch intensity from mosquito bite; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17412405 chr5:114880687 FEM1C -0.56 -6.24 -0.32 1.33e-9 Systolic blood pressure; LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg13409248 chr3:40428643 ENTPD3 -0.5 -8.41 -0.41 1.15e-15 Renal cell carcinoma; LIHC cis rs1008375 1.000 rs2159584 chr4:17620568 G/A cg02297831 chr4:17616191 MED28 0.48 7.38 0.37 1.24e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2243480 1.000 rs34136756 chr7:65381256 A/G cg10756647 chr7:56101905 PSPH 1.09 13.52 0.59 1.17e-33 Diabetic kidney disease; LIHC cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg19318889 chr4:1322082 MAEA -0.47 -6.56 -0.33 1.96e-10 Obesity-related traits; LIHC cis rs1949733 0.628 rs2688231 chr4:8490981 G/A cg11789530 chr4:8429930 ACOX3 0.76 10.89 0.51 6.38e-24 Response to antineoplastic agents; LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg02475777 chr4:1388615 CRIPAK 0.4 6.15 0.32 2.15e-9 Obesity-related traits; LIHC trans rs11098499 0.954 rs10005644 chr4:120298477 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg00280220 chr17:61926910 NA -0.39 -6.26 -0.32 1.13e-9 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs9902453 0.933 rs9303628 chr17:28527228 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.62 9.65 0.46 1.16e-19 Coffee consumption (cups per day); LIHC cis rs67460515 0.892 rs34771618 chr3:161059795 A/C cg17135325 chr3:160939158 NMD3 0.56 8.25 0.41 3.54e-15 Parkinson's disease; LIHC cis rs4332037 0.539 rs3823624 chr7:2110346 T/C cg23422044 chr7:1970798 MAD1L1 -0.51 -5.93 -0.31 7.59e-9 Bipolar disorder; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg10150615 chr22:24372951 LOC391322 -0.57 -8.45 -0.42 8.77e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2204008 0.774 rs12810027 chr12:38212165 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC trans rs6489882 0.902 rs3815178 chr12:113376320 C/T cg10175203 chr3:128143634 NA 0.38 6.17 0.32 1.96e-9 Chronic lymphocytic leukemia; LIHC cis rs62103177 0.608 rs59300126 chr18:77694439 C/A cg20368463 chr18:77673604 PQLC1 0.54 6.64 0.34 1.26e-10 Opioid sensitivity; LIHC cis rs1892700 0.764 rs78478169 chr21:34906428 T/C cg14850771 chr21:34775459 IFNGR2 -0.45 -5.91 -0.3 8.47e-9 Educational attainment; LIHC cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg05564831 chr3:52568323 NT5DC2 0.38 6.16 0.32 2.07e-9 Bipolar disorder; LIHC cis rs7618501 1.000 rs11716575 chr3:49744890 A/G cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.558 rs9444530 chr6:88343318 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.39 6.85 0.35 3.53e-11 Monocyte percentage of white cells; LIHC cis rs17376456 0.877 rs9314099 chr5:93447375 T/C cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs4759375 0.748 rs73230017 chr12:123418231 G/A cg25930673 chr12:123319894 HIP1R 0.6 5.92 0.31 7.72e-9 HDL cholesterol; LIHC cis rs2439831 0.867 rs2412780 chr15:43655794 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.93 17.36 0.68 7.38e-49 Lung cancer in ever smokers; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg22903471 chr2:27725779 GCKR -0.5 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs7208859 0.623 rs9899692 chr17:29156939 C/T cg13385521 chr17:29058706 SUZ12P 0.82 7.99 0.4 2.16e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs892961 0.899 rs747482 chr17:75412109 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.68e-13 Airflow obstruction; LIHC cis rs427394 0.735 rs416689 chr5:6740855 C/T cg10857441 chr5:6722123 POLS -0.37 -6.45 -0.33 3.73e-10 Menopause (age at onset); LIHC cis rs2204008 0.558 rs66545149 chr12:38204694 A/G cg26384229 chr12:38710491 ALG10B 0.88 10.83 0.51 1.1e-23 Bladder cancer; LIHC cis rs2072499 0.898 rs2758609 chr1:156202868 G/A cg25208724 chr1:156163844 SLC25A44 0.57 9.46 0.46 5.2e-19 Testicular germ cell tumor; LIHC cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg26939375 chr7:64535504 NA 0.47 7.14 0.36 5.64e-12 Aortic root size; LIHC cis rs2115630 0.905 rs6496401 chr15:85297793 A/T cg12501888 chr15:85177176 SCAND2 -0.5 -7.79 -0.39 8.05e-14 P wave terminal force; LIHC cis rs12142240 0.698 rs45517837 chr1:46859225 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC cis rs2302777 0.507 rs9889711 chr17:38108292 A/T cg17344932 chr17:38183730 MED24;SNORD124 -0.47 -7.0 -0.35 1.32e-11 Multiple myeloma (hyperdiploidy); LIHC cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.45 6.36 0.33 6.33e-10 Mean platelet volume; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg06873352 chr17:61820015 STRADA 0.75 13.7 0.6 2.43e-34 Prudent dietary pattern; LIHC cis rs1552244 0.882 rs13099507 chr3:10031603 G/A cg08888203 chr3:10149979 C3orf24 0.49 6.07 0.31 3.45e-9 Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07284286 chr16:58662935 CNOT1 0.48 7.06 0.36 9.47e-12 Lung function (FEV1/FVC); LIHC cis rs8177179 0.505 rs1405023 chr3:133481128 T/C cg16262614 chr3:133464971 TF -0.34 -6.93 -0.35 2.1e-11 Iron status biomarkers (transferrin levels); LIHC cis rs918629 0.567 rs7716691 chr5:95237040 C/T cg10483112 chr5:95245456 ELL2 -0.37 -6.83 -0.35 3.84e-11 IgG glycosylation; LIHC cis rs9911578 0.867 rs4793941 chr17:56472366 G/A cg12560992 chr17:57184187 TRIM37 -0.92 -15.35 -0.64 8.04e-41 Intelligence (multi-trait analysis); LIHC cis rs1538970 0.962 rs2153609 chr1:45814058 A/G cg05343316 chr1:45956843 TESK2 0.55 8.19 0.41 5.15e-15 Platelet count; LIHC cis rs3784262 1.000 rs4646619 chr15:58258342 A/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.38 -0.33 5.77e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs611744 0.967 rs602384 chr8:109188185 G/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg22481606 chr17:56429567 SUPT4H1 -0.4 -6.44 -0.33 4.14e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg26354017 chr1:205819088 PM20D1 0.85 12.57 0.56 4.66e-30 Menarche (age at onset); LIHC cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg13012494 chr21:47604986 C21orf56 0.4 6.12 0.31 2.56e-9 Testicular germ cell tumor; LIHC trans rs4824093 0.545 rs58876234 chr22:50258868 G/A cg09872104 chr7:134855509 C7orf49 -0.76 -6.09 -0.31 2.99e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg24101359 chr6:42928495 GNMT 0.46 5.95 0.31 6.73e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2153535 0.580 rs9393033 chr6:8521446 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.22e-26 Motion sickness; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09426994 chr11:118478258 PHLDB1 -0.44 -6.04 -0.31 4.04e-9 Longevity; LIHC cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.1 0.44 7.66e-18 Platelet count; LIHC cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg07061783 chr6:25882402 NA -0.47 -6.53 -0.33 2.38e-10 Blood metabolite levels; LIHC cis rs6964587 0.967 rs34040612 chr7:91798916 G/T cg17063962 chr7:91808500 NA 1.02 20.23 0.74 2.11e-60 Breast cancer; LIHC cis rs17685 0.753 rs10245584 chr7:75745866 C/T cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19613905 chr15:56757180 MNS1 0.49 7.53 0.38 4.46e-13 Pancreatic cancer; LIHC cis rs7772486 0.846 rs1331636 chr6:146338826 T/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.1 -0.31 2.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17001868 0.527 rs9611324 chr22:40781162 T/C cg07138101 chr22:40742427 ADSL 0.53 6.46 0.33 3.67e-10 Mammographic density (dense area); LIHC cis rs6138458 1.000 rs11905625 chr20:24977065 A/C cg26195577 chr20:24973756 C20orf3 1.2 16.23 0.66 2.61e-44 Blood protein levels; LIHC cis rs1577917 0.917 rs35283633 chr6:86690787 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.52 -0.33 2.46e-10 Response to antipsychotic treatment; LIHC cis rs2180341 0.680 rs9388554 chr6:127576234 C/G cg24812749 chr6:127587940 RNF146 0.66 9.75 0.47 5.4e-20 Breast cancer; LIHC cis rs62179067 0.708 rs11885400 chr2:179936237 G/T cg07532576 chr2:179544947 TTN 0.61 5.8 0.3 1.49e-8 Late-onset Alzheimer's disease; LIHC cis rs35110281 0.837 rs12627667 chr21:45071396 A/C cg21573476 chr21:45109991 RRP1B -0.51 -9.68 -0.46 9.91e-20 Mean corpuscular volume; LIHC trans rs66573146 0.572 rs67252699 chr4:6946411 A/G cg07817883 chr1:32538562 TMEM39B 1.03 9.14 0.44 5.57e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg15691649 chr6:25882328 NA -0.37 -5.86 -0.3 1.07e-8 Height; LIHC cis rs7129556 0.520 rs7943742 chr11:77268856 C/T cg03570279 chr11:77446074 RSF1 -0.36 -6.68 -0.34 9.43e-11 Weight loss (gastric bypass surgery); LIHC cis rs477895 0.713 rs1059440 chr11:63991801 C/T cg18225595 chr11:63971243 STIP1 -0.68 -8.51 -0.42 5.57e-16 Mean platelet volume; LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs11758351 0.660 rs11753655 chr6:26220109 C/T cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs11190604 1.000 rs7088512 chr10:102303498 G/T cg07080220 chr10:102295463 HIF1AN 0.52 7.39 0.37 1.17e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs77106637 0.860 rs7129793 chr11:72455885 C/T cg03713592 chr11:72463424 ARAP1 1.17 10.46 0.49 2.17e-22 Type 2 diabetes; LIHC cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.7 0.69 3.05e-50 Gut microbiome composition (summer); LIHC cis rs9296092 0.538 rs75652975 chr6:33516251 C/T cg13560919 chr6:33536144 NA -0.39 -6.29 -0.32 9.47e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7131987 0.868 rs737160 chr12:29429012 T/C cg00204748 chr12:29376779 FAR2 0.34 6.48 0.33 3.22e-10 QT interval; LIHC cis rs9611565 0.649 rs5758466 chr22:42176059 G/A cg03806693 chr22:41940476 POLR3H 0.8 8.66 0.42 1.84e-16 Vitiligo; LIHC cis rs73001065 0.901 rs73004926 chr19:19671266 C/T cg03709012 chr19:19516395 GATAD2A 0.91 7.84 0.39 5.79e-14 LDL cholesterol; LIHC cis rs7546668 1.000 rs1467513 chr1:15894959 T/C cg11706911 chr1:15910989 AGMAT 0.45 6.75 0.34 6.42e-11 Glomerular filtration rate (creatinine); LIHC cis rs35096708 1.000 rs35096708 chr16:89887249 G/A cg03809021 chr16:89831123 FANCA 0.55 6.28 0.32 9.99e-10 Skin aging (microtopography measurement); LIHC cis rs13040088 1.000 rs12480117 chr20:61558274 G/A cg23096297 chr20:61557774 DIDO1 0.85 11.34 0.52 1.6e-25 Menopause (age at onset); LIHC cis rs7520050 1.000 rs12410070 chr1:46358882 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.42 6.13 0.31 2.45e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1577917 0.652 rs75593931 chr6:86719539 A/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.82 -0.35 4.09e-11 Response to antipsychotic treatment; LIHC cis rs6882046 0.513 rs628158 chr5:88041781 G/A cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs11190604 1.000 rs2298075 chr10:102247408 C/A cg07080220 chr10:102295463 HIF1AN 0.5 7.08 0.36 8.02e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17401966 0.931 rs11587854 chr1:10447622 G/A cg19773385 chr1:10388646 KIF1B -0.38 -6.54 -0.33 2.24e-10 Hepatocellular carcinoma; LIHC trans rs941408 0.928 rs2741991 chr19:2802092 T/C cg19676328 chr12:49525230 TUBA1B -0.44 -6.36 -0.33 6.31e-10 Total cholesterol levels; LIHC cis rs4819052 0.851 rs2838840 chr21:46668494 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.33 0.52 1.74e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7089973 0.604 rs7923693 chr10:116619566 A/G cg03647239 chr10:116582469 FAM160B1 0.46 6.75 0.34 6.33e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7116495 1.000 rs4944258 chr11:71743393 T/A cg26138937 chr11:71823887 C11orf51 -0.82 -8.15 -0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs561341 1.000 rs554078 chr17:30330109 A/C cg00745463 chr17:30367425 LRRC37B -0.8 -5.79 -0.3 1.57e-8 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.722 rs10025925 chr4:120271744 A/T cg25214090 chr10:38739885 LOC399744 0.45 7.48 0.37 6.21e-13 Corneal astigmatism; LIHC cis rs72627123 0.619 rs79575309 chr14:74590230 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.87 8.47 0.42 7.59e-16 Morning vs. evening chronotype; LIHC cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg07061783 chr6:25882402 NA -0.7 -9.51 -0.46 3.59e-19 Blood metabolite levels; LIHC cis rs4908760 0.613 rs12024032 chr1:8808185 A/G cg20416874 chr1:8611966 RERE 0.53 8.98 0.44 1.83e-17 Vitiligo; LIHC cis rs74181299 0.684 rs11126028 chr2:65338150 C/G cg05010058 chr2:65284262 CEP68 -0.36 -6.01 -0.31 4.82e-9 Pulse pressure; LIHC cis rs727505 1.000 rs56313563 chr7:124507003 G/A cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.34e-9 Lewy body disease; LIHC cis rs1385374 0.858 rs11059928 chr12:129296103 A/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.77 0.39 9e-14 Systemic lupus erythematosus; LIHC cis rs17253792 0.822 rs75351812 chr14:56082192 G/A cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09048334 chr6:37012640 NA 0.46 6.25 0.32 1.21e-9 Hepatitis; LIHC cis rs1008375 0.932 rs10029173 chr4:17659598 C/T cg02297831 chr4:17616191 MED28 -0.47 -7.26 -0.37 2.59e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7412746 0.658 rs6658066 chr1:150918937 T/G cg15448220 chr1:150897856 SETDB1 0.43 6.91 0.35 2.36e-11 Melanoma; LIHC cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg03517284 chr6:25882590 NA -0.5 -6.15 -0.32 2.18e-9 Intelligence (multi-trait analysis); LIHC trans rs916888 0.821 rs70602 chr17:44859715 T/C cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7249142 0.527 rs12975096 chr19:19279409 G/T cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.37 -6.21 -0.32 1.56e-9 IgG glycosylation; LIHC cis rs6912958 0.525 rs242262 chr6:88018057 A/C cg12350822 chr6:88032061 C6orf162;GJB7 0.35 6.81 0.35 4.5e-11 Monocyte percentage of white cells; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs72627123 0.867 rs112965033 chr14:74461117 T/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.85 8.17 0.4 6.07e-15 Morning vs. evening chronotype; LIHC cis rs4713118 0.662 rs149901 chr6:27965503 C/T cg16479474 chr6:28041457 NA 0.43 6.65 0.34 1.15e-10 Parkinson's disease; LIHC cis rs4906332 1.000 rs35862113 chr14:103857229 G/T cg19000871 chr14:103996768 TRMT61A -0.44 -7.4 -0.37 1.04e-12 Coronary artery disease; LIHC cis rs72781680 0.752 rs55859418 chr2:23904231 C/A cg08917208 chr2:24149416 ATAD2B 0.98 8.06 0.4 1.29e-14 Lymphocyte counts; LIHC cis rs748404 0.587 rs9920879 chr15:43639770 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.89 0.43 3.56e-17 Lung cancer; LIHC cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg08132940 chr7:1081526 C7orf50 -0.79 -6.72 -0.34 7.83e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7116495 0.609 rs4945392 chr11:71694645 C/T cg07596299 chr11:71824057 C11orf51 -0.75 -5.72 -0.3 2.3e-8 Severe influenza A (H1N1) infection; LIHC cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg10360323 chr17:41437877 NA 0.41 6.09 0.31 3.1e-9 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13670615 chr19:49140625 SEC1;DBP 0.45 6.69 0.34 9.27e-11 Lung function (FEV1/FVC); LIHC cis rs28830936 1.000 rs9672360 chr15:41912411 T/C cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.2 -0.32 1.59e-9 Diastolic blood pressure; LIHC cis rs2070433 0.756 rs2839295 chr21:47917871 A/T cg12379764 chr21:47803548 PCNT 0.64 9.0 0.44 1.55e-17 Lymphocyte counts; LIHC cis rs2836950 0.762 rs8134638 chr21:40644170 T/C cg11890956 chr21:40555474 PSMG1 -0.4 -5.85 -0.3 1.14e-8 Menarche (age at onset); LIHC cis rs507080 0.885 rs7926959 chr11:118559866 T/C cg04173919 chr11:118528438 PHLDB1 0.35 6.59 0.34 1.62e-10 Serum metabolite levels; LIHC cis rs3096299 0.748 rs3102339 chr16:89442711 C/T cg01788221 chr16:89496183 ANKRD11 -0.4 -6.26 -0.32 1.17e-9 Multiple myeloma (IgH translocation); LIHC cis rs6430585 0.528 rs309151 chr2:136661150 C/T cg07305463 chr2:136567211 LCT -0.38 -5.87 -0.3 1.02e-8 Corneal structure; LIHC cis rs10197940 0.662 rs13555 chr2:152333304 C/A cg06191203 chr2:152266755 RIF1 -0.44 -7.58 -0.38 3.27e-13 Lung cancer; LIHC cis rs1008375 0.900 rs1003413 chr4:17582442 C/T cg16339924 chr4:17578868 LAP3 -0.57 -7.41 -0.37 9.68e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9596863 0.898 rs9563177 chr13:54368853 A/G ch.13.53330881F chr13:54432880 NA 0.43 5.8 0.3 1.53e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs10751667 0.643 rs7396767 chr11:938808 G/A cg10932868 chr11:921992 NA 0.38 7.34 0.37 1.59e-12 Alzheimer's disease (late onset); LIHC cis rs2832191 0.692 rs2776240 chr21:30310639 C/T cg08807101 chr21:30365312 RNF160 0.75 10.63 0.5 5.19e-23 Dental caries; LIHC cis rs2842992 0.789 rs2842969 chr6:160145364 C/T cg11366901 chr6:160182831 ACAT2 0.96 16.32 0.66 1.1e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs7635838 0.819 rs12714866 chr3:11539058 C/T cg00170343 chr3:11313890 ATG7 0.4 6.21 0.32 1.54e-9 HDL cholesterol; LIHC trans rs801193 1.000 rs1553610 chr7:66197233 T/C cg26939375 chr7:64535504 NA 0.42 6.82 0.35 4.26e-11 Aortic root size; LIHC cis rs9640161 0.750 rs3735169 chr7:150034378 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.54 -8.75 -0.43 1e-16 Blood protein levels;Circulating chemerin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07087156 chr2:228190257 NA 0.43 6.51 0.33 2.6200000000000003e-10 Lung function (FEV1/FVC); LIHC cis rs7312933 0.558 rs1796381 chr12:42842475 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.57 8.84 0.43 5.04e-17 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1580019 0.713 rs2167274 chr7:32524844 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.56 8.16 0.4 6.48e-15 Cognitive ability; LIHC cis rs2228479 0.850 rs62054640 chr16:89823157 C/T cg19635926 chr16:89946313 TCF25 0.49 6.21 0.32 1.56e-9 Skin colour saturation; LIHC cis rs2836974 0.644 rs719230 chr21:40676307 C/T cg11890956 chr21:40555474 PSMG1 -0.5 -7.99 -0.4 2.13e-14 Cognitive function; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08005411 chr12:69753742 YEATS4 0.45 6.28 0.32 1.02e-9 Lung function (FEV1/FVC); LIHC cis rs1129187 0.748 rs6458312 chr6:42904274 G/T cg02353165 chr6:42928485 GNMT 0.52 7.64 0.38 2.24e-13 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs11098499 0.566 rs7664440 chr4:120578540 A/G cg25214090 chr10:38739885 LOC399744 0.53 8.22 0.41 4.4e-15 Corneal astigmatism; LIHC cis rs4407350 0.870 rs5765714 chr22:44915203 T/C cg11695653 chr22:44894386 LDOC1L -0.36 -6.2 -0.32 1.6e-9 Intelligence (multi-trait analysis); LIHC trans rs783540 0.967 rs7494860 chr15:83334419 A/G cg18393722 chr15:85113863 UBE2QP1 0.36 6.29 0.32 9.73e-10 Schizophrenia; LIHC cis rs10847980 0.623 rs28613486 chr12:123867268 T/C cg00376283 chr12:123451042 ABCB9 0.62 6.57 0.33 1.92e-10 Adiponectin levels; LIHC trans rs6598955 0.671 rs10493030 chr1:26561856 T/C cg07461501 chr17:79650226 HGS;ARL16 -0.81 -9.1 -0.44 7.57e-18 Obesity-related traits; LIHC cis rs66887589 0.807 rs9799664 chr4:120326678 C/T cg09307838 chr4:120376055 NA 0.48 7.23 0.36 3.21e-12 Diastolic blood pressure; LIHC cis rs919433 0.617 rs2037590 chr2:198584775 T/A cg03934865 chr2:198174659 NA -0.48 -7.04 -0.36 1.04e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3008870 0.583 rs3008861 chr1:67396222 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.87 13.3 0.58 8.03e-33 Lymphocyte percentage of white cells; LIHC cis rs9443189 0.570 rs659807 chr6:76293435 C/A cg01950844 chr6:76311363 SENP6 0.91 11.43 0.53 7.43e-26 Prostate cancer; LIHC cis rs4908768 0.906 rs12145445 chr1:8604370 C/G cg20416874 chr1:8611966 RERE 0.57 8.73 0.43 1.16e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs611744 0.905 rs677031 chr8:109152068 G/A cg18478394 chr8:109455254 TTC35 0.34 5.75 0.3 1.95e-8 Dupuytren's disease; LIHC cis rs703842 0.560 rs11533604 chr12:58047713 G/A cg15848620 chr12:58087721 OS9 0.5 6.26 0.32 1.18e-9 Multiple sclerosis; LIHC cis rs1499614 0.901 rs3936 chr7:66126489 C/T cg12463550 chr7:65579703 CRCP 0.67 6.96 0.35 1.77e-11 Gout; LIHC cis rs36051895 0.659 rs1576271 chr9:5039652 A/C cg02405213 chr9:5042618 JAK2 -0.7 -12.3 -0.55 5.02e-29 Pediatric autoimmune diseases; LIHC cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.26 -0.61 1.61e-36 Alzheimer's disease; LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg17178900 chr1:205818956 PM20D1 0.74 11.17 0.52 6.82e-25 Menarche (age at onset); LIHC cis rs763121 0.853 rs5750677 chr22:39147715 C/T cg06544989 chr22:39130855 UNC84B 0.38 5.95 0.31 6.53e-9 Menopause (age at onset); LIHC cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg05590025 chr7:65112418 INTS4L2 -0.62 -6.82 -0.35 4.26e-11 Diabetic kidney disease; LIHC cis rs427394 0.632 rs2279656 chr5:6737576 G/A cg10857441 chr5:6722123 POLS -0.39 -6.61 -0.34 1.47e-10 Menopause (age at onset); LIHC cis rs950776 0.518 rs12903129 chr15:78819606 C/T cg06917634 chr15:78832804 PSMA4 0.93 14.23 0.61 2.05e-36 Sudden cardiac arrest; LIHC cis rs7618501 1.000 rs7634902 chr3:49762662 G/T cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC cis rs11608355 0.545 rs7316375 chr12:109906998 G/C cg05360138 chr12:110035743 NA 0.95 10.81 0.5 1.29e-23 Neuroticism; LIHC trans rs4704846 0.660 rs246882 chr5:156559014 G/A cg02632742 chr2:60187357 NA -0.6 -6.04 -0.31 3.99e-9 Blood protein levels; LIHC cis rs9309711 0.883 rs13429373 chr2:3477014 G/A cg10845886 chr2:3471009 TTC15 -0.63 -11.83 -0.54 2.57e-27 Neurofibrillary tangles; LIHC cis rs1707322 1.000 rs4073847 chr1:46463012 A/C cg06784218 chr1:46089804 CCDC17 -0.34 -5.94 -0.31 6.85e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6831352 0.734 rs1311620 chr4:100013091 C/T cg12011299 chr4:100065546 ADH4 0.57 10.01 0.48 7.51e-21 Alcohol dependence; LIHC trans rs1005277 0.579 rs1780133 chr10:38499509 T/C cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs3008870 1.000 rs1118393 chr1:67366668 A/G cg02640540 chr1:67518911 SLC35D1 0.44 6.05 0.31 3.77e-9 Lymphocyte percentage of white cells; LIHC cis rs2304069 0.909 rs2544931 chr5:149367837 C/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.97 -12.37 -0.56 2.71e-29 HIV-1 control; LIHC trans rs2739330 0.892 rs4822455 chr22:24255296 C/T cg06437703 chr8:37914619 EIF4EBP1 -0.5 -7.36 -0.37 1.34e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6964587 1.000 rs36021614 chr7:91717490 C/G cg17063962 chr7:91808500 NA 0.99 18.43 0.71 3.79e-53 Breast cancer; LIHC cis rs9325144 0.534 rs4882350 chr12:38686979 A/G cg26384229 chr12:38710491 ALG10B 0.6 8.43 0.41 9.62e-16 Morning vs. evening chronotype; LIHC trans rs12478296 1.000 rs55814222 chr2:243041166 C/T cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.95e-15 Obesity-related traits; LIHC cis rs2239547 0.657 rs12488303 chr3:52862003 G/A cg11645453 chr3:52864694 ITIH4 0.34 8.83 0.43 5.49e-17 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19050596 chr2:191879164 STAT1 0.43 6.15 0.32 2.1e-9 Pancreatic cancer; LIHC cis rs597539 0.652 rs514296 chr11:68654182 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.78 11.98 0.54 7.35e-28 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6424115 0.867 rs11588187 chr1:24145047 T/A cg15997130 chr1:24165203 NA 0.47 9.72 0.47 7.12e-20 Immature fraction of reticulocytes; LIHC cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg05754148 chr16:3507555 NAT15 0.38 6.28 0.32 1e-9 Tuberculosis; LIHC cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg15534755 chr11:117069859 TAGLN 0.39 6.59 0.34 1.63e-10 Blood protein levels; LIHC cis rs903552 0.800 rs1587107 chr15:102006485 T/C cg00659931 chr15:102010125 PCSK6 -0.49 -6.51 -0.33 2.63e-10 Diabetic kidney disease; LIHC cis rs4919087 0.892 rs10786319 chr10:99008951 T/C cg25902810 chr10:99078978 FRAT1 0.63 8.97 0.44 1.92e-17 Monocyte count; LIHC cis rs9322817 0.902 rs9404576 chr6:105184640 T/G cg02098413 chr6:105308735 HACE1 -0.39 -6.54 -0.33 2.23e-10 Thyroid stimulating hormone; LIHC cis rs921968 0.643 rs520095 chr2:219329485 C/T cg18887096 chr2:219472410 PLCD4 0.4 6.96 0.35 1.79e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs10744422 0.920 rs3896871 chr12:123333610 G/T cg07706471 chr12:123319906 HIP1R -0.62 -8.23 -0.41 4.12e-15 Schizophrenia; LIHC trans rs11098499 0.954 rs28685688 chr4:120420334 T/C cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.43 0.62 3.28e-37 Prudent dietary pattern; LIHC cis rs12477438 0.520 rs4850897 chr2:99768419 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC trans rs7618501 0.633 rs12485600 chr3:50025530 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.51 0.46 3.49e-19 Intelligence (multi-trait analysis); LIHC cis rs13161895 1.000 rs4389651 chr5:179460968 T/A cg02702477 chr5:179499311 RNF130 0.75 10.44 0.49 2.46e-22 LDL cholesterol; LIHC cis rs8067545 0.611 rs10491107 chr17:20188174 C/T cg13482628 chr17:19912719 NA 0.46 7.47 0.37 6.72e-13 Schizophrenia; LIHC cis rs11098499 0.754 rs12513083 chr4:120249612 A/T cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.14e-25 Corneal astigmatism; LIHC cis rs67981189 0.593 rs10140917 chr14:71491820 T/C cg15816911 chr14:71606274 NA 0.41 6.52 0.33 2.54e-10 Schizophrenia; LIHC cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg14343924 chr8:8086146 FLJ10661 0.47 6.46 0.33 3.6e-10 Systolic blood pressure; LIHC cis rs28374715 0.681 rs11629979 chr15:41626579 A/G cg18705301 chr15:41695430 NDUFAF1 -0.98 -13.35 -0.59 4.98e-33 Ulcerative colitis; LIHC trans rs61931739 0.500 rs10844734 chr12:34043083 G/A cg26384229 chr12:38710491 ALG10B 0.45 6.41 0.33 4.71e-10 Morning vs. evening chronotype; LIHC cis rs72843506 0.656 rs10459970 chr17:19937341 G/A cg12065943 chr17:19881925 AKAP10 -0.41 -6.93 -0.35 2.14e-11 Schizophrenia; LIHC cis rs904251 0.523 rs914348 chr6:37484729 G/A cg08126542 chr6:37504118 NA -0.35 -5.95 -0.31 6.82e-9 Cognitive performance; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg19373090 chr19:797215 PTBP1 -0.6 -6.77 -0.34 5.5e-11 Systolic blood pressure; LIHC cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg06238570 chr21:40685208 BRWD1 -0.53 -8.74 -0.43 1.04e-16 Cognitive function; LIHC cis rs694739 0.726 rs516124 chr11:64128423 G/T cg23796481 chr11:64053134 BAD;GPR137 0.47 6.37 0.33 6.06e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg24209194 chr3:40518798 ZNF619 0.44 6.3 0.32 9.19e-10 Renal cell carcinoma; LIHC cis rs2963155 0.518 rs174048 chr5:142650404 T/C cg17617527 chr5:142782415 NR3C1 0.95 10.75 0.5 2.04e-23 Breast cancer; LIHC cis rs924607 0.510 rs1709542 chr5:662543 A/G cg07001201 chr5:642380 CEP72 -0.37 -6.66 -0.34 1.09e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg10862848 chr6:42927986 GNMT -0.26 -6.1 -0.31 2.88e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7116495 0.867 rs481300 chr11:71578383 G/A cg26138937 chr11:71823887 C11orf51 0.7 6.86 0.35 3.27e-11 Severe influenza A (H1N1) infection; LIHC cis rs2228479 0.702 rs11076621 chr16:89837927 A/G cg04013166 chr16:89971882 TCF25 0.53 6.69 0.34 8.94e-11 Skin colour saturation; LIHC cis rs11792861 1.000 rs11792861 chr9:111809295 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.87 0.43 4.21e-17 Menarche (age at onset); LIHC cis rs17125944 0.615 rs7145392 chr14:53321016 G/A cg00686598 chr14:53173677 PSMC6 -0.78 -9.03 -0.44 1.3e-17 Alzheimer's disease (late onset); LIHC cis rs922107 0.701 rs2125723 chr1:90031845 C/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.65 -0.38 2.04e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs10242455 0.702 rs73711280 chr7:99039604 C/T cg18809830 chr7:99032528 PTCD1 -0.82 -6.37 -0.33 5.95e-10 Blood metabolite levels; LIHC cis rs10504229 0.565 rs7010503 chr8:58147127 G/A cg20607798 chr8:58055168 NA 0.51 6.45 0.33 3.82e-10 Developmental language disorder (linguistic errors); LIHC cis rs4665809 1.000 rs4233710 chr2:26291565 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.36 -0.45 1.06e-18 Gut microbiome composition (summer); LIHC cis rs4764124 1.000 rs4764124 chr12:14966604 C/T cg19759883 chr12:14956454 WBP11;C12orf60 0.43 7.17 0.36 4.8e-12 Pubertal anthropometrics; LIHC cis rs2576037 0.583 rs892586 chr18:44560429 C/A cg19077165 chr18:44547161 KATNAL2 0.48 7.1 0.36 7.11e-12 Personality dimensions; LIHC cis rs9583531 0.527 rs9515274 chr13:111390429 A/G cg24331049 chr13:111365604 ING1 0.64 10.61 0.5 6.41e-23 Coronary artery disease; LIHC cis rs3806843 1.000 rs1548701 chr5:140164557 T/C cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs2727020 0.729 rs34647977 chr11:49195543 G/A cg03929089 chr4:120376271 NA -0.8 -14.11 -0.61 5.8e-36 Coronary artery disease; LIHC trans rs4578769 0.918 rs6507457 chr18:20626436 C/T cg04130657 chr1:161102858 DEDD 0.39 6.35 0.32 6.89e-10 Eosinophil percentage of white cells; LIHC cis rs9583531 0.574 rs7319459 chr13:111352408 T/C cg15841412 chr13:111365552 ING1 -0.47 -5.93 -0.31 7.47e-9 Coronary artery disease; LIHC cis rs2404602 0.618 rs12442266 chr15:76567142 T/C cg23625390 chr15:77176239 SCAPER 0.34 5.92 0.3 7.87e-9 Blood metabolite levels; LIHC cis rs12540874 0.522 rs4947641 chr7:50489038 C/T cg18232548 chr7:50535776 DDC -0.41 -6.24 -0.32 1.29e-9 Systemic sclerosis; LIHC cis rs9858542 1.000 rs3197999 chr3:49721532 G/A cg03060546 chr3:49711283 APEH -0.67 -8.97 -0.44 2e-17 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9389248 0.690 rs1028314 chr6:135255710 A/C cg24558204 chr6:135376177 HBS1L -0.59 -9.62 -0.46 1.55e-19 High light scatter reticulocyte percentage of red cells; LIHC cis rs3736485 0.966 rs11070862 chr15:51902227 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.21 -0.32 1.54e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs798554 0.757 rs1182187 chr7:2870454 T/G cg19717773 chr7:2847554 GNA12 -0.43 -6.49 -0.33 3e-10 Height; LIHC cis rs11098699 0.821 rs931705 chr4:124205194 C/T cg09941581 chr4:124220074 SPATA5 0.32 6.38 0.33 5.62e-10 Mosquito bite size; LIHC cis rs1577917 0.916 rs12198730 chr6:86555138 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.52 -0.38 4.83e-13 Response to antipsychotic treatment; LIHC cis rs7572733 0.534 rs7557203 chr2:198795650 A/G cg03934865 chr2:198174659 NA 0.45 6.64 0.34 1.26e-10 Dermatomyositis; LIHC cis rs7412746 0.658 rs11204739 chr1:150865760 A/G cg17724175 chr1:150552817 MCL1 0.41 8.17 0.4 6.08e-15 Melanoma; LIHC cis rs8180040 0.902 rs73081205 chr3:47517670 A/C cg16586182 chr3:47516702 SCAP 0.61 11.96 0.54 9.17e-28 Colorectal cancer; LIHC cis rs1005277 0.691 rs2474558 chr10:38486141 A/C cg23084528 chr10:38645450 HSD17B7P2 0.43 6.02 0.31 4.4e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7937890 0.598 rs10734225 chr11:14442994 C/G cg02886208 chr11:14281011 SPON1 -0.53 -7.27 -0.37 2.43e-12 Mitochondrial DNA levels; LIHC cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg07234388 chr1:156261841 TMEM79 -0.5 -8.95 -0.44 2.37e-17 Tonsillectomy; LIHC cis rs8062405 0.625 rs8060365 chr16:28911309 C/A cg07451762 chr16:28383216 NA -0.37 -6.43 -0.33 4.31e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10492096 1.000 rs12422771 chr12:6580273 G/T cg13857086 chr12:6580257 VAMP1 0.61 6.08 0.31 3.16e-9 Hip geometry; LIHC cis rs240764 0.817 rs12207086 chr6:101150463 G/A cg09795085 chr6:101329169 ASCC3 -0.51 -6.86 -0.35 3.26e-11 Neuroticism; LIHC cis rs1577917 1.000 rs12190598 chr6:86686074 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.55 -0.33 2.14e-10 Response to antipsychotic treatment; LIHC cis rs798554 0.797 rs2107964 chr7:2863574 G/A cg19524238 chr7:2802976 GNA12 -0.4 -5.79 -0.3 1.61e-8 Height; LIHC cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.91 8.23 0.41 3.98e-15 Platelet count; LIHC cis rs1552244 0.882 rs68153882 chr3:10013110 T/C cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC trans rs208520 0.690 rs207102 chr6:66795671 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs875971 0.545 rs7811204 chr7:65852200 G/A cg11764359 chr7:65958608 NA 0.6 8.43 0.41 1.01e-15 Aortic root size; LIHC cis rs9733 0.596 rs11807058 chr1:150640475 G/A cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs7618501 0.501 rs35275715 chr3:49959148 A/G cg05623727 chr3:50126028 RBM5 0.34 5.79 0.3 1.61e-8 Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06253862 chr6:160201362 SNORA20;TCP1 0.51 6.5 0.33 2.77e-10 Systolic blood pressure; LIHC cis rs7772486 0.790 rs80050589 chr6:146230454 T/C cg23711669 chr6:146136114 FBXO30 -0.71 -12.36 -0.56 2.98e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.967 rs11626011 chr14:90693572 A/G cg14092571 chr14:90743983 NA -0.4 -6.25 -0.32 1.2e-9 Mortality in heart failure; LIHC cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg21448741 chr8:58168803 NA 0.35 5.75 0.3 1.99e-8 Developmental language disorder (linguistic errors); LIHC cis rs739401 0.527 rs423236 chr11:3065916 C/T cg08508325 chr11:3079039 CARS -0.34 -7.2 -0.36 3.75e-12 Longevity; LIHC cis rs4965272 0.830 rs11637820 chr15:100560239 C/T cg09918751 chr15:100517450 ADAMTS17 0.45 6.25 0.32 1.19e-9 Gastroesophageal reflux disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg27074985 chr4:111118232 ELOVL6 0.42 6.65 0.34 1.16e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11676348 0.791 rs6726126 chr2:218952233 G/A cg00012203 chr2:219082015 ARPC2 -0.55 -7.67 -0.38 1.86e-13 Ulcerative colitis; LIHC cis rs2032447 0.507 rs478349 chr6:25894057 T/C cg03517284 chr6:25882590 NA -1.06 -13.52 -0.59 1.14e-33 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg11644478 chr21:40555479 PSMG1 0.79 9.9 0.47 1.7e-20 Cognitive function; LIHC cis rs2153535 0.580 rs1119689 chr6:8460754 C/G cg21535247 chr6:8435926 SLC35B3 0.64 8.35 0.41 1.77e-15 Motion sickness; LIHC cis rs9660992 0.710 rs1768587 chr1:205236432 C/T cg21545522 chr1:205238299 TMCC2 0.43 8.13 0.4 8.01e-15 Mean corpuscular volume;Mean platelet volume; LIHC cis rs3736485 0.966 rs10851500 chr15:51783820 T/C cg08986416 chr15:51914746 DMXL2 -0.4 -6.05 -0.31 3.78e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7927771 0.832 rs11039212 chr11:47393303 A/T cg20307385 chr11:47447363 PSMC3 0.44 5.73 0.3 2.22e-8 Subjective well-being; LIHC cis rs2439831 0.681 rs999047 chr15:43688916 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.93 0.51 4.89e-24 Lung cancer in ever smokers; LIHC cis rs7520050 0.966 rs11211234 chr1:46438787 C/A cg03146154 chr1:46216737 IPP -0.38 -6.26 -0.32 1.17e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7615952 0.512 rs1077621 chr3:125819799 A/G cg05084668 chr3:125655381 ALG1L -0.4 -6.05 -0.31 3.88e-9 Blood pressure (smoking interaction); LIHC cis rs2012796 0.956 rs7147254 chr14:81820503 G/A cg02996355 chr14:81879375 NA 0.45 6.79 0.34 5.04e-11 Night sleep phenotypes; LIHC cis rs11792861 0.926 rs72607174 chr9:111899132 A/T cg05043794 chr9:111880884 C9orf5 -0.3 -6.91 -0.35 2.42e-11 Menarche (age at onset); LIHC cis rs10504073 0.545 rs4406405 chr8:49957261 G/C cg00325661 chr8:49890786 NA 0.34 7.65 0.38 2.03e-13 Blood metabolite ratios; LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.28 0.41 2.88e-15 Height; LIHC cis rs7208859 0.623 rs9890855 chr17:29111707 G/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4820539 0.902 rs4822359 chr22:23474972 A/G cg14186256 chr22:23484241 RTDR1 0.97 21.07 0.75 9.06e-64 Bone mineral density; LIHC cis rs10504229 0.724 rs72649117 chr8:58037639 A/G cg20607798 chr8:58055168 NA 0.46 6.62 0.34 1.42e-10 Developmental language disorder (linguistic errors); LIHC cis rs6502050 0.835 rs8071425 chr17:80117335 C/T cg11859384 chr17:80120422 CCDC57 0.45 6.13 0.31 2.43e-9 Life satisfaction; LIHC cis rs9790314 1.000 rs1600209 chr3:161038217 A/T cg03342759 chr3:160939853 NMD3 -0.7 -8.34 -0.41 1.83e-15 Morning vs. evening chronotype; LIHC cis rs7107174 1.000 rs11237471 chr11:78082604 C/T cg02023728 chr11:77925099 USP35 0.4 7.42 0.37 9.4e-13 Testicular germ cell tumor; LIHC cis rs2228479 0.702 rs62053702 chr16:89860688 G/T cg06558623 chr16:89946397 TCF25 0.85 11.09 0.51 1.32e-24 Skin colour saturation; LIHC cis rs9486719 1.000 rs67996804 chr6:96884387 C/T cg06623918 chr6:96969491 KIAA0776 -0.73 -7.27 -0.37 2.41e-12 Migraine;Coronary artery disease; LIHC cis rs3888647 0.561 rs4758617 chr11:2995185 T/A cg08508325 chr11:3079039 CARS -0.27 -5.9 -0.3 8.82e-9 Type 2 diabetes; LIHC cis rs6062302 0.522 rs6089929 chr20:62219679 C/T cg09650180 chr20:62225654 GMEB2 -0.38 -5.9 -0.3 8.81e-9 Glioblastoma; LIHC cis rs7827545 0.644 rs3739427 chr8:135524938 T/C cg17885191 chr8:135476712 NA -0.36 -6.18 -0.32 1.78e-9 Hypertension (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg25894440 chr7:65020034 NA -0.53 -6.11 -0.31 2.72e-9 Diabetic kidney disease; LIHC trans rs11098499 0.874 rs6826823 chr4:120112098 G/C cg25214090 chr10:38739885 LOC399744 0.45 7.25 0.36 2.86e-12 Corneal astigmatism; LIHC cis rs9325144 0.555 rs2387847 chr12:38687434 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.43 0.41 9.62e-16 Morning vs. evening chronotype; LIHC cis rs561341 0.769 rs12941700 chr17:30185022 A/G cg13647721 chr17:30228624 UTP6 -0.69 -6.16 -0.32 2e-9 Hip circumference adjusted for BMI; LIHC cis rs1670533 0.932 rs3796620 chr4:1095079 A/G cg27284194 chr4:1044797 NA -0.61 -8.99 -0.44 1.73e-17 Recombination rate (females); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03130149 chr11:3819041 PGAP2;NUP98 0.38 6.12 0.31 2.58e-9 Cognitive function; LIHC cis rs1552244 0.572 rs58862481 chr3:10164308 G/A cg00149659 chr3:10157352 C3orf10 1.13 9.99 0.48 8.57e-21 Alzheimer's disease; LIHC cis rs3749237 0.595 rs12489092 chr3:49550914 G/C cg03060546 chr3:49711283 APEH 0.6 9.77 0.47 4.93e-20 Resting heart rate; LIHC trans rs6563898 0.915 rs6563892 chr16:83348255 A/G cg13016115 chr14:23388406 RBM23 -0.42 -6.13 -0.31 2.49e-9 IgE levels in asthmatics (D.f. specific); LIHC cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg11301795 chr4:187892539 NA -0.27 -7.05 -0.36 1e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01301323 chr12:77252588 CSRP2 -0.4 -6.64 -0.34 1.22e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3096299 0.685 rs2911244 chr16:89521860 A/G cg01788221 chr16:89496183 ANKRD11 -0.37 -5.75 -0.3 1.99e-8 Multiple myeloma (IgH translocation); LIHC cis rs2075371 1.000 rs2058976 chr7:133981379 G/T cg20476274 chr7:133979776 SLC35B4 0.75 12.69 0.57 1.7e-30 Mean platelet volume; LIHC cis rs17685 0.753 rs869806 chr7:75688623 C/T cg01364799 chr7:75623366 TMEM120A -0.51 -7.79 -0.39 8.1e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7903847 0.642 rs10882911 chr10:99138064 A/C cg20016023 chr10:99160130 RRP12 -0.42 -6.51 -0.33 2.65e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs546131 0.890 rs496558 chr11:34826425 C/T cg06937548 chr11:34938143 PDHX;APIP 0.56 7.51 0.38 5.21e-13 Lung disease severity in cystic fibrosis; LIHC cis rs611744 0.647 rs7015513 chr8:109262570 A/C cg21045802 chr8:109455806 TTC35 0.58 10.23 0.48 1.32e-21 Dupuytren's disease; LIHC cis rs12500138 1.000 rs114597618 chr4:166169289 A/G cg25064052 chr4:166216151 KLHL2 -0.67 -6.15 -0.32 2.14e-9 Cognitive function; LIHC cis rs992157 1.000 rs736731 chr2:219120588 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.88 0.57 3.23e-31 Colorectal cancer; LIHC cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg17554472 chr22:41940697 POLR3H 0.54 5.9 0.3 8.82e-9 Vitiligo; LIHC cis rs10752881 1.000 rs4420053 chr1:182976133 A/C ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.64 5.71 0.3 2.43e-8 Platelet count; LIHC cis rs2257205 0.667 rs4340382 chr17:56738919 G/A cg05425664 chr17:57184151 TRIM37 -0.59 -6.47 -0.33 3.49e-10 Pancreatic cancer; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg15667495 chr17:40719620 MLX -0.41 -6.37 -0.33 6.25e-10 Triglycerides; LIHC cis rs2191566 0.664 rs55958002 chr19:44543788 A/T cg20607764 chr19:44506953 ZNF230 -0.37 -6.22 -0.32 1.45e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg14159672 chr1:205819179 PM20D1 0.72 10.25 0.48 1.16e-21 Menarche (age at onset); LIHC cis rs12142240 0.698 rs56909107 chr1:46808224 A/C cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs1005277 0.579 rs1780136 chr10:38501453 A/G cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs7959452 0.640 rs10878957 chr12:69699638 G/C cg22834771 chr12:69754056 YEATS4 -0.47 -8.06 -0.4 1.32e-14 Blood protein levels; LIHC cis rs853679 0.517 rs3173443 chr6:28137027 T/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs6088590 1.000 rs6088590 chr20:33313566 T/C cg24642439 chr20:33292090 TP53INP2 0.8 11.59 0.53 1.95e-26 Coronary artery disease; LIHC cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg23205692 chr1:25664452 TMEM50A 0.37 5.75 0.3 1.95e-8 Erythrocyte sedimentation rate; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26926833 chr16:30194886 CORO1A 0.43 6.32 0.32 8.38e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs208520 1.000 rs72884025 chr6:66994185 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 7.14 0.36 5.52e-12 Exhaled nitric oxide output; LIHC cis rs637571 0.565 rs633800 chr11:65638719 G/A cg26695010 chr11:65641043 EFEMP2 0.57 7.82 0.39 6.76e-14 Eosinophil percentage of white cells; LIHC cis rs11628318 0.563 rs1190344 chr14:103097912 A/G cg23461800 chr14:103021989 NA -0.4 -5.99 -0.31 5.24e-9 Platelet count; LIHC cis rs8103278 1.000 rs36091860 chr19:46312880 G/A cg14061069 chr19:46274453 DMPK -0.55 -8.57 -0.42 3.73e-16 Coronary artery disease; LIHC cis rs798554 0.679 rs1614791 chr7:2888057 G/T cg19346786 chr7:2764209 NA -0.36 -5.79 -0.3 1.63e-8 Height; LIHC cis rs28830936 0.966 rs28451764 chr15:42126583 A/G cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.8 -0.3 1.51e-8 Diastolic blood pressure; LIHC cis rs9814567 1.000 rs6772896 chr3:134203347 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.7 -12.47 -0.56 1.12e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs55665837 0.701 rs12787709 chr11:14639257 G/A cg19336497 chr11:14380999 RRAS2 -0.36 -5.76 -0.3 1.92e-8 Vitamin D levels; LIHC cis rs950169 0.922 rs11633075 chr15:85113972 C/A cg03959625 chr15:84868606 LOC388152 0.44 6.03 0.31 4.19e-9 Schizophrenia; LIHC cis rs2839186 0.721 rs3788252 chr21:47661235 C/T cg12016809 chr21:47604291 C21orf56 0.46 6.91 0.35 2.34e-11 Testicular germ cell tumor; LIHC cis rs3857067 1.000 rs6532463 chr4:95027048 G/T cg11021082 chr4:95130006 SMARCAD1 -0.41 -7.35 -0.37 1.43e-12 QT interval; LIHC cis rs250677 1.000 rs36082 chr5:148428844 C/G cg18129178 chr5:148520854 ABLIM3 -0.49 -6.63 -0.34 1.3100000000000001e-10 Breast cancer; LIHC cis rs9457247 1.000 rs422562 chr6:167406318 A/G cg12798992 chr6:167411361 FGFR1OP 0.62 10.03 0.48 6.57e-21 Crohn's disease; LIHC cis rs7107174 1.000 rs58565853 chr11:78036707 C/T cg02023728 chr11:77925099 USP35 0.5 9.55 0.46 2.69e-19 Testicular germ cell tumor; LIHC cis rs9768139 0.733 rs35016950 chr7:158118710 C/A cg25566285 chr7:158114605 PTPRN2 0.23 6.12 0.31 2.5e-9 Calcium levels; LIHC cis rs2932538 0.961 rs3795820 chr1:113163042 C/A cg22162597 chr1:113214053 CAPZA1 -0.72 -9.72 -0.47 7e-20 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1018836 0.545 rs7840203 chr8:91701223 A/G cg16814680 chr8:91681699 NA -0.96 -18.11 -0.7 7.31e-52 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9916302 0.653 rs11654954 chr17:37745979 C/T cg07936489 chr17:37558343 FBXL20 0.5 6.55 0.33 2.09e-10 Glomerular filtration rate (creatinine); LIHC cis rs6690583 0.623 rs11588160 chr1:85444226 T/G cg22153463 chr1:85462885 MCOLN2 0.52 6.23 0.32 1.34e-9 Serum sulfate level; LIHC cis rs7520050 0.931 rs6686134 chr1:46378268 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.92 0.3 7.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg00149659 chr3:10157352 C3orf10 0.61 6.75 0.34 6.38e-11 Alzheimer's disease; LIHC cis rs2075371 0.611 rs11762920 chr7:134018514 C/T cg20476274 chr7:133979776 SLC35B4 0.48 6.41 0.33 4.93e-10 Mean platelet volume; LIHC cis rs1348850 0.561 rs4893956 chr2:178373452 C/T cg27490568 chr2:178487706 NA 1.0 11.25 0.52 3.51e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs61931739 0.500 rs7489132 chr12:34539712 C/T cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs2933343 0.621 rs789249 chr3:128578453 T/C cg24203234 chr3:128598194 ACAD9 0.43 5.95 0.31 6.79e-9 IgG glycosylation; LIHC cis rs12477438 0.539 rs720228 chr2:99704547 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.84 15.1 0.63 7.64e-40 Chronic sinus infection; LIHC cis rs8017423 0.967 rs7154683 chr14:90700692 A/G cg04374321 chr14:90722782 PSMC1 0.75 14.45 0.62 2.74e-37 Mortality in heart failure; LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs950169 0.922 rs17531523 chr15:85132449 C/G cg03959625 chr15:84868606 LOC388152 0.47 6.43 0.33 4.31e-10 Schizophrenia; LIHC cis rs6964587 1.000 rs7811564 chr7:91663364 A/G cg17063962 chr7:91808500 NA 1.02 19.65 0.73 4.62e-58 Breast cancer; LIHC cis rs6918586 0.636 rs198816 chr6:26127184 C/T cg18357526 chr6:26021779 HIST1H4A -0.57 -8.63 -0.42 2.43e-16 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00838250 chr3:186287958 TBCCD1;DNAJB11 0.48 7.18 0.36 4.29e-12 Cognitive function; LIHC cis rs8017423 0.967 rs11623275 chr14:90721335 C/T cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 2.97e-9 Mortality in heart failure; LIHC cis rs801193 0.935 rs11772264 chr7:66176387 T/C cg18876405 chr7:65276391 NA 0.43 7.34 0.37 1.58e-12 Aortic root size; LIHC cis rs7618501 0.521 rs55692411 chr3:49911155 G/A cg05623727 chr3:50126028 RBM5 0.37 6.15 0.32 2.18e-9 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16242708 chr19:40596726 ZNF780A 0.48 6.24 0.32 1.27e-9 Lung function (FEV1/FVC); LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg04267008 chr7:1944627 MAD1L1 -0.65 -10.74 -0.5 2.21e-23 Bipolar disorder and schizophrenia; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg19422253 chr3:149212391 TM4SF4 0.56 6.16 0.32 2.07e-9 Mean platelet volume; LIHC cis rs3823572 0.564 rs4728305 chr7:133666949 C/T cg03336402 chr7:133662267 EXOC4 -0.47 -5.72 -0.3 2.29e-8 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg06656553 chr16:89960601 TCF25 -0.5 -6.47 -0.33 3.34e-10 Skin colour saturation; LIHC cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs2242116 1.000 rs2168443 chr3:46947087 A/T cg27129171 chr3:47204927 SETD2 -0.46 -7.36 -0.37 1.38e-12 Birth weight; LIHC cis rs881375 0.678 rs7037195 chr9:123684000 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 6.31 0.32 8.85e-10 Rheumatoid arthritis; LIHC cis rs9640161 0.711 rs3800781 chr7:150027324 T/A cg17279839 chr7:150038598 RARRES2 0.56 11.38 0.52 1.13e-25 Blood protein levels;Circulating chemerin levels; LIHC cis rs1144333 0.510 rs1250882 chr1:76287314 C/A cg10523679 chr1:76189770 ACADM -0.44 -5.91 -0.3 8.23e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs240764 0.817 rs58266877 chr6:101156284 C/T cg09795085 chr6:101329169 ASCC3 -0.54 -7.51 -0.38 5.06e-13 Neuroticism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11682216 chr4:68411177 CENPC1 -0.48 -6.76 -0.34 6.14e-11 Pancreatic cancer; LIHC trans rs7618501 1.000 rs7648987 chr3:49868455 A/G cg21659725 chr3:3221576 CRBN 0.96 18.62 0.71 6.55e-54 Intelligence (multi-trait analysis); LIHC cis rs3784262 1.000 rs4646629 chr15:58255215 A/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.38 -0.33 5.65e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg21280719 chr6:42927975 GNMT -0.37 -7.95 -0.39 2.81e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs11031096 0.678 rs12292724 chr11:4176671 T/A cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.33e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs8062405 0.755 rs111693583 chr16:28583610 C/T cg07451762 chr16:28383216 NA 0.38 6.87 0.35 3.09e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11229555 0.598 rs11229426 chr11:58180063 T/C cg15696309 chr11:58395628 NA -0.66 -7.76 -0.39 1.02e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs17401966 0.838 rs4846207 chr1:10313811 T/C cg19773385 chr1:10388646 KIF1B -0.4 -7.3 -0.37 2.04e-12 Hepatocellular carcinoma; LIHC cis rs9733 0.593 rs10888384 chr1:150574256 C/T cg18016565 chr1:150552671 MCL1 -0.54 -10.98 -0.51 3.14e-24 Tonsillectomy; LIHC cis rs9378688 1.000 rs3800187 chr6:2222253 C/T cg12303981 chr6:2244766 GMDS -0.49 -6.22 -0.32 1.48e-9 Caudate nucleus volume; LIHC cis rs611744 0.934 rs624311 chr8:109204437 A/G cg21045802 chr8:109455806 TTC35 0.52 8.88 0.43 3.94e-17 Dupuytren's disease; LIHC cis rs12971120 0.891 rs3794955 chr18:72174827 C/T cg25817165 chr18:72167213 CNDP2 -0.72 -12.35 -0.56 3.11e-29 Refractive error; LIHC cis rs2236918 1.000 rs1629051 chr1:242026344 A/G cg17736920 chr1:242011382 EXO1 -0.57 -8.63 -0.42 2.43e-16 Menopause (age at onset); LIHC cis rs6952808 0.543 rs4719436 chr7:2141239 G/A cg21782813 chr7:2030301 MAD1L1 0.38 6.56 0.33 2.04e-10 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs9379210 chr6:8461928 C/G cg21535247 chr6:8435926 SLC35B3 0.63 8.26 0.41 3.22e-15 Motion sickness; LIHC cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.93 8.57 0.42 3.56e-16 Platelet count; LIHC cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg16405210 chr4:1374714 KIAA1530 -0.9 -14.29 -0.61 1.14e-36 Longevity; LIHC cis rs4635969 0.718 rs27068 chr5:1347239 C/T cg07493874 chr5:1342172 CLPTM1L -0.46 -6.08 -0.31 3.19e-9 Testicular germ cell tumor;Testicular germ cell cancer; LIHC trans rs10411161 1.000 rs3848562 chr19:52379835 C/T cg22319618 chr22:45562946 NUP50 0.56 7.8 0.39 7.66e-14 Breast cancer; LIHC cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7552404 1.000 rs4559448 chr1:76203456 A/G cg10523679 chr1:76189770 ACADM 0.63 8.71 0.43 1.3e-16 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15235185 chr1:193028809 TROVE2;UCHL5 0.4 6.06 0.31 3.51e-9 Pancreatic cancer; LIHC cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1639906 0.965 rs1637750 chr7:2227811 A/G cg02951883 chr7:2050386 MAD1L1 0.38 5.74 0.3 2.13e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs6952808 0.594 rs3778964 chr7:2138109 C/T cg04267008 chr7:1944627 MAD1L1 -0.53 -8.38 -0.41 1.44e-15 Bipolar disorder and schizophrenia; LIHC cis rs2839186 0.559 rs2277826 chr21:47639492 C/G cg12016809 chr21:47604291 C21orf56 -0.4 -5.86 -0.3 1.09e-8 Testicular germ cell tumor; LIHC cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg04944784 chr2:26401820 FAM59B 0.72 9.25 0.45 2.57e-18 Gut microbiome composition (summer); LIHC cis rs5751150 1 rs5751150 chr22:42153292 T/G cg03806693 chr22:41940476 POLR3H 0.98 10.28 0.49 8.96e-22 Cannabis dependence symptom count; LIHC cis rs3793683 0.928 rs2148666 chr10:134553785 A/G cg27286337 chr10:134555280 INPP5A 1.02 19.57 0.73 9.58e-58 Migraine; LIHC trans rs6489882 0.867 rs4766672 chr12:113365148 A/G cg10175203 chr3:128143634 NA 0.39 6.36 0.33 6.4e-10 Chronic lymphocytic leukemia; LIHC cis rs1707322 0.717 rs1972410 chr1:46080947 G/T cg06784218 chr1:46089804 CCDC17 0.4 7.14 0.36 5.82e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.908 rs138891 chr22:50227741 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -8.75 -0.43 9.93e-17 Schizophrenia; LIHC cis rs1552244 0.882 rs13075842 chr3:10055813 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.71 9.82 0.47 3.25e-20 Alzheimer's disease; LIHC cis rs8180040 0.627 rs58956475 chr3:47224615 G/C cg16586182 chr3:47516702 SCAP 0.48 8.54 0.42 4.56e-16 Colorectal cancer; LIHC cis rs11098499 0.708 rs11732686 chr4:120252330 C/A cg09307838 chr4:120376055 NA 0.71 11.02 0.51 2.19e-24 Corneal astigmatism; LIHC cis rs10870270 1.000 rs3935905 chr10:133758262 A/C cg17892150 chr10:133769511 PPP2R2D -0.69 -13.03 -0.58 8.44e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1552244 0.882 rs6443279 chr3:10053599 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.63 -9.1 -0.44 7.75e-18 Alzheimer's disease; LIHC cis rs7224685 0.906 rs9915922 chr17:4083242 T/C cg11204139 chr17:3907470 NA 0.62 8.63 0.42 2.38e-16 Type 2 diabetes; LIHC cis rs12188164 0.525 rs2561665 chr5:460135 A/G cg07599136 chr5:415885 AHRR 0.39 6.65 0.34 1.14e-10 Cystic fibrosis severity; LIHC cis rs67311347 0.822 rs11709089 chr3:40351484 C/T cg18306943 chr3:40428807 ENTPD3 0.35 5.82 0.3 1.39e-8 Renal cell carcinoma; LIHC cis rs1707322 0.721 rs11211181 chr1:46236800 C/T cg03146154 chr1:46216737 IPP 0.59 10.28 0.49 9.1e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17125944 0.505 rs80211268 chr14:53265483 C/G cg00686598 chr14:53173677 PSMC6 1.32 16.34 0.66 8.98e-45 Alzheimer's disease (late onset); LIHC cis rs7762018 0.891 rs1981069 chr6:170148837 G/A cg19338460 chr6:170058176 WDR27 -0.38 -5.9 -0.3 8.61e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs896854 0.516 rs12679044 chr8:95891356 C/A cg13393036 chr8:95962371 TP53INP1 -0.4 -8.83 -0.43 5.45e-17 Type 2 diabetes; LIHC cis rs651907 0.557 rs7651721 chr3:101393583 C/A cg11279151 chr3:101281821 RG9MTD1 -0.42 -6.46 -0.33 3.6e-10 Colorectal cancer; LIHC cis rs9790314 0.560 rs4856701 chr3:161044106 G/T cg17135325 chr3:160939158 NMD3 0.41 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs2425143 0.908 rs58448091 chr20:34325470 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.84 -0.3 1.2e-8 Blood protein levels; LIHC cis rs1048238 0.506 rs848195 chr1:16286522 A/G cg00529422 chr1:16285251 ZBTB17 0.34 6.57 0.33 1.92e-10 Systolic blood pressure; LIHC cis rs9733 0.596 rs7538493 chr1:150655421 T/C cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Tonsillectomy; LIHC trans rs1728785 1.000 rs1728765 chr16:68589433 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.41 0.33 4.71e-10 Ulcerative colitis; LIHC cis rs4642101 0.618 rs9877079 chr3:12821287 A/G cg24848339 chr3:12840334 CAND2 0.31 6.44 0.33 4.04e-10 QRS complex (12-leadsum); LIHC cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs10751667 0.643 rs10751666 chr11:941933 C/T ch.11.42038R chr11:967971 AP2A2 0.55 9.92 0.47 1.51e-20 Alzheimer's disease (late onset); LIHC cis rs2576037 0.561 rs513775 chr18:44396334 T/C cg19077165 chr18:44547161 KATNAL2 -0.44 -6.68 -0.34 9.49e-11 Personality dimensions; LIHC cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg23978390 chr7:1156363 C7orf50 0.56 8.56 0.42 4e-16 Longevity;Endometriosis; LIHC cis rs2836950 0.501 rs1474490 chr21:40716136 C/A cg06238570 chr21:40685208 BRWD1 -0.38 -6.06 -0.31 3.55e-9 Menarche (age at onset); LIHC cis rs7134594 0.539 rs7294688 chr12:110054765 C/G cg05360138 chr12:110035743 NA -0.42 -6.06 -0.31 3.54e-9 HDL cholesterol; LIHC trans rs7615952 0.611 rs2947646 chr3:125593602 C/T cg07211511 chr3:129823064 LOC729375 0.74 7.79 0.39 8.11e-14 Blood pressure (smoking interaction); LIHC cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.61 -0.46 1.65e-19 Bipolar disorder; LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg18306943 chr3:40428807 ENTPD3 -0.42 -7.46 -0.37 7.36e-13 Renal cell carcinoma; LIHC cis rs804280 0.662 rs11250164 chr8:11610686 C/T cg00832105 chr8:11331707 NA 0.3 5.78 0.3 1.66e-8 Myopia (pathological); LIHC cis rs11792861 0.926 rs7870597 chr9:111871864 T/C cg05043794 chr9:111880884 C9orf5 -0.31 -7.24 -0.36 3.07e-12 Menarche (age at onset); LIHC trans rs9926296 0.618 rs8058179 chr16:89846987 C/T cg06755612 chr14:45603778 FKBP3;FANCM -0.49 -6.12 -0.31 2.59e-9 Vitiligo; LIHC cis rs4888262 0.545 rs4072450 chr16:74666634 G/C cg01733217 chr16:74700730 RFWD3 0.87 16.43 0.66 4.18e-45 Testicular germ cell tumor; LIHC cis rs9457247 0.663 rs7749278 chr6:167435325 C/T cg12798992 chr6:167411361 FGFR1OP -0.5 -7.82 -0.39 6.5e-14 Crohn's disease; LIHC cis rs9393692 0.645 rs6939048 chr6:26327953 G/A cg13736514 chr6:26305472 NA -0.4 -6.24 -0.32 1.28e-9 Educational attainment; LIHC cis rs801193 0.569 rs6978178 chr7:66123084 G/A cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs1707322 1.000 rs1707337 chr1:46508769 A/G cg03146154 chr1:46216737 IPP -0.45 -7.4 -0.37 1.05e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs924607 0.898 rs1697990 chr5:626278 A/G cg24163568 chr5:669837 TPPP -0.37 -8.03 -0.4 1.62e-14 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg10360323 chr17:41437877 NA 0.39 5.73 0.3 2.23e-8 Menopause (age at onset); LIHC cis rs3892630 0.588 rs1976501 chr19:33208155 C/T cg22980127 chr19:33182716 NUDT19 1.04 13.48 0.59 1.63e-33 Red blood cell traits; LIHC cis rs16958440 0.867 rs75808931 chr18:44693042 C/T cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs2073300 1.000 rs78000067 chr20:23439507 A/G cg16736954 chr20:23401023 NAPB 0.54 6.02 0.31 4.6e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7927771 0.524 rs10742817 chr11:47689343 A/G cg20307385 chr11:47447363 PSMC3 -0.78 -11.94 -0.54 1.05e-27 Subjective well-being; LIHC cis rs3008870 0.755 rs1570838 chr1:67403315 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.77 0.5 1.73e-23 Lymphocyte percentage of white cells; LIHC cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg25894440 chr7:65020034 NA -0.53 -6.04 -0.31 4.05e-9 Diabetic kidney disease; LIHC cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg10560079 chr2:191398806 TMEM194B 0.51 7.93 0.39 3.24e-14 Pulse pressure; LIHC trans rs352889 1.000 rs352892 chr2:143757925 G/T cg11565512 chr5:126627355 MEGF10 0.22 6.07 0.31 3.39e-9 Toenail selenium levels; LIHC trans rs2727020 0.638 rs1164668 chr11:49330627 A/C cg15704280 chr7:45808275 SEPT13 0.89 16.23 0.66 2.63e-44 Coronary artery disease; LIHC cis rs2073300 0.609 rs6137919 chr20:23363163 T/C cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg16822855 chr3:40428330 ENTPD3 0.33 6.0 0.31 4.96e-9 Renal cell carcinoma; LIHC cis rs4808199 0.947 rs1465695 chr19:19588546 A/C cg03709012 chr19:19516395 GATAD2A 1.08 19.27 0.72 1.45e-56 Nonalcoholic fatty liver disease; LIHC trans rs8117834 0.605 rs12480533 chr20:8082896 A/G cg00593689 chr4:53575888 NA 0.38 6.5 0.33 2.77e-10 Chronic kidney disease; LIHC cis rs35110281 0.837 rs2838342 chr21:45077865 G/A cg01579765 chr21:45077557 HSF2BP -0.3 -5.72 -0.3 2.31e-8 Mean corpuscular volume; LIHC cis rs9640161 0.750 rs11769348 chr7:150026753 C/T cg27494647 chr7:150038898 RARRES2 -0.32 -5.8 -0.3 1.53e-8 Blood protein levels;Circulating chemerin levels; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg23556447 chr6:90529595 MDN1 -0.39 -6.05 -0.31 3.76e-9 Body mass index; LIHC cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg16434002 chr17:42200994 HDAC5 0.51 7.41 0.37 9.76e-13 Total body bone mineral density; LIHC cis rs916888 0.773 rs199535 chr17:44822662 A/G cg15921436 chr17:44337874 NA 0.67 6.71 0.34 7.89e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs12479064 0.694 rs4341989 chr2:100046783 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.6 -7.68 -0.38 1.7e-13 Chronic sinus infection; LIHC cis rs9868809 0.881 rs7620853 chr3:48666503 G/A cg07636037 chr3:49044803 WDR6 -0.53 -6.15 -0.32 2.16e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21515243 chr18:21033072 RIOK3 0.49 7.42 0.37 9.16e-13 Pancreatic cancer; LIHC cis rs7586673 0.930 rs2884364 chr2:161977647 G/A cg08807892 chr2:162101083 NA 0.37 5.89 0.3 9.25e-9 Intelligence (multi-trait analysis); LIHC cis rs546131 0.642 rs11602870 chr11:34841902 C/G cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.49 -0.33 3.05e-10 Lung disease severity in cystic fibrosis; LIHC cis rs12701220 0.655 rs7799656 chr7:1140515 C/T cg16145915 chr7:1198662 ZFAND2A -0.35 -7.04 -0.36 1.08e-11 Bronchopulmonary dysplasia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07569756 chr17:48474564 LRRC59 0.43 6.23 0.32 1.39e-9 Pancreatic cancer; LIHC cis rs4906332 1.000 rs34347076 chr14:103955069 G/A cg19000871 chr14:103996768 TRMT61A -0.46 -7.86 -0.39 5.04e-14 Coronary artery disease; LIHC cis rs763121 0.853 rs5750622 chr22:38956464 C/G cg21395723 chr22:39101663 GTPBP1 0.37 5.78 0.3 1.67e-8 Menopause (age at onset); LIHC cis rs10876993 0.890 rs12302350 chr12:58062589 T/G cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.57 -0.33 1.86e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Bipolar disorder; LIHC cis rs10508774 0.850 rs2152161 chr10:32932785 T/A cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs5769707 0.632 rs1476037 chr22:49991377 G/A cg01652190 chr22:50026171 C22orf34 -0.33 -7.39 -0.37 1.14e-12 Monocyte count;Monocyte percentage of white cells; LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg06719391 chr11:2554330 KCNQ1 -0.55 -6.28 -0.32 1.06e-9 Bronchial neuroendocrine tumor; LIHC cis rs10028773 0.568 rs6838457 chr4:120267367 A/G cg09307838 chr4:120376055 NA 0.63 9.88 0.47 2.07e-20 Educational attainment; LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg14393609 chr7:65229607 NA 0.41 6.91 0.35 2.39e-11 Calcium levels; LIHC trans rs2243480 1.000 rs36033484 chr7:65390558 T/G cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs12188164 0.543 rs2672722 chr5:453567 G/A cg16584290 chr5:462447 EXOC3 0.36 5.94 0.31 7.06e-9 Cystic fibrosis severity; LIHC trans rs7618501 0.602 rs2071207 chr3:50159844 T/C cg21659725 chr3:3221576 CRBN -0.67 -10.79 -0.5 1.5e-23 Intelligence (multi-trait analysis); LIHC cis rs4268898 0.662 rs17733015 chr2:24509370 A/G cg06627628 chr2:24431161 ITSN2 -0.71 -9.54 -0.46 2.73e-19 Asthma; LIHC cis rs9916302 0.904 rs612194 chr17:37442707 T/A cg03013999 chr17:37608204 MED1 -0.36 -6.06 -0.31 3.53e-9 Glomerular filtration rate (creatinine); LIHC cis rs60871478 0.947 rs4074610 chr7:791755 G/A cg05535760 chr7:792225 HEATR2 0.79 11.22 0.52 4.36e-25 Cerebrospinal P-tau181p levels; LIHC cis rs6964587 1.000 rs4265 chr7:91719608 A/G cg17063962 chr7:91808500 NA -0.99 -18.63 -0.71 5.83e-54 Breast cancer; LIHC cis rs9517313 0.707 rs9517298 chr13:99095003 C/T cg22223119 chr13:99095684 FARP1 -0.39 -5.84 -0.3 1.23e-8 Neuroticism; LIHC cis rs16958440 0.867 rs9304342 chr18:44720199 T/G cg17192377 chr18:44677553 HDHD2 0.91 8.68 0.42 1.64e-16 Sitting height ratio; LIHC cis rs3736485 0.899 rs6493505 chr15:51845172 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.29 -0.32 9.83e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs875971 0.660 rs7807930 chr7:66087165 C/T cg18876405 chr7:65276391 NA -0.44 -7.62 -0.38 2.57e-13 Aortic root size; LIHC cis rs739401 0.611 rs12284275 chr11:3024384 T/C cg25174290 chr11:3078921 CARS 0.61 9.19 0.45 3.76e-18 Longevity; LIHC cis rs965469 0.545 rs6051845 chr20:3402792 A/G cg25506879 chr20:3388711 C20orf194 -0.46 -6.28 -0.32 1.02e-9 IFN-related cytopenia; LIHC cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg23758822 chr17:41437982 NA 0.93 17.8 0.69 1.27e-50 Menopause (age at onset); LIHC cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg25072359 chr17:41440525 NA 0.37 5.95 0.31 6.5e-9 Menopause (age at onset); LIHC cis rs7100689 0.622 rs2994389 chr10:82062257 C/G cg01528321 chr10:82214614 TSPAN14 0.83 11.06 0.51 1.62e-24 Post bronchodilator FEV1; LIHC cis rs748404 0.560 rs2255663 chr15:43829008 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.39 -5.81 -0.3 1.39e-8 Lung cancer; LIHC cis rs7511006 0.893 rs760743 chr22:50647375 C/T cg16473166 chr22:50639996 SELO 0.6 8.82 0.43 5.88e-17 Obesity-related traits; LIHC cis rs4888262 0.526 rs6564145 chr16:74621129 G/A cg01733217 chr16:74700730 RFWD3 0.83 16.02 0.65 1.79e-43 Testicular germ cell tumor; LIHC cis rs916888 0.821 rs199513 chr17:44856932 A/G cg15921436 chr17:44337874 NA -0.63 -6.73 -0.34 7.1e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs798554 0.679 rs2533877 chr7:2882421 G/A cg04166393 chr7:2884313 GNA12 0.52 8.2 0.41 4.9e-15 Height; LIHC cis rs6754311 0.731 rs1470457 chr2:136581848 A/G cg25344623 chr2:136566232 LCT -0.35 -6.84 -0.35 3.65e-11 Mosquito bite size; LIHC cis rs769267 0.930 rs6909 chr19:19619542 A/G cg03709012 chr19:19516395 GATAD2A 1.01 17.93 0.7 3.71e-51 Tonsillectomy; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs769267 0.930 rs1054284 chr19:19616953 T/G cg03709012 chr19:19516395 GATAD2A 1.0 17.72 0.69 2.59e-50 Tonsillectomy; LIHC cis rs1577917 1.000 rs35761942 chr6:86629504 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.15 -0.36 5.28e-12 Response to antipsychotic treatment; LIHC trans rs11724903 0.935 rs10520526 chr4:183217796 C/T cg16239906 chr20:35724590 RBL1 -0.63 -6.07 -0.31 3.3e-9 Smoking initiation; LIHC cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs8141529 0.732 rs2347447 chr22:29179739 C/A cg15103426 chr22:29168792 CCDC117 0.67 11.68 0.53 9.46e-27 Lymphocyte counts; LIHC cis rs597539 0.652 rs602364 chr11:68662167 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.93 0.51 4.9e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.684 rs12437981 chr15:76842401 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.31 -0.45 1.62e-18 Blood metabolite levels; LIHC cis rs11673344 0.764 rs565721 chr19:37455831 G/A cg27390819 chr19:37464633 NA -0.53 -6.29 -0.32 9.74e-10 Obesity-related traits; LIHC cis rs763121 0.626 rs5757236 chr22:39073824 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.39 0.52 1.05e-25 Menopause (age at onset); LIHC cis rs1005277 0.691 rs2474558 chr10:38486141 A/C cg03665457 chr10:38645376 HSD17B7P2 0.44 6.09 0.31 3.12e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1816752 0.905 rs1050112 chr13:25009297 G/T cg02811702 chr13:24901961 NA 0.25 6.24 0.32 1.3e-9 Obesity-related traits; LIHC cis rs10193935 0.901 rs222483 chr2:42652184 T/G cg27598129 chr2:42591480 NA -0.68 -10.02 -0.48 7.02e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs910316 0.737 rs424120 chr14:75482828 G/T cg11812906 chr14:75593930 NEK9 -0.73 -13.75 -0.6 1.54e-34 Height; LIHC cis rs7615952 0.534 rs1503072 chr3:125754691 C/T cg05084668 chr3:125655381 ALG1L -0.41 -6.35 -0.32 6.66e-10 Blood pressure (smoking interaction); LIHC cis rs8072100 1.000 rs8065437 chr17:45721653 C/T cg08085267 chr17:45401833 C17orf57 -0.56 -8.33 -0.41 2e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10751667 0.600 rs10794342 chr11:924904 C/T cg10932868 chr11:921992 NA 0.39 7.49 0.38 5.97e-13 Alzheimer's disease (late onset); LIHC trans rs208520 0.955 rs12204033 chr6:67001525 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 6.91 0.35 2.36e-11 Exhaled nitric oxide output; LIHC cis rs10870270 1.000 rs72636963 chr10:133771271 C/T cg17892150 chr10:133769511 PPP2R2D -0.68 -12.73 -0.57 1.23e-30 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9921222 0.565 rs1805105 chr16:396264 A/G cg26913058 chr16:419975 MRPL28 -0.49 -7.33 -0.37 1.64e-12 Bone mineral density (spine);Bone mineral density; LIHC cis rs12824058 0.831 rs4759451 chr12:130812739 G/A cg24229701 chr12:130821962 PIWIL1 0.44 6.81 0.35 4.49e-11 Menopause (age at onset); LIHC cis rs11758351 1.000 rs112751982 chr6:26191958 C/T cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs12497850 0.931 rs13064911 chr3:48952385 A/G cg07636037 chr3:49044803 WDR6 0.92 16.52 0.67 1.74e-45 Parkinson's disease; LIHC cis rs7107174 1.000 rs2248407 chr11:77937800 G/A cg02023728 chr11:77925099 USP35 0.44 8.62 0.42 2.45e-16 Testicular germ cell tumor; LIHC cis rs1707322 1.000 rs11211223 chr1:46380605 C/T cg03146154 chr1:46216737 IPP 0.47 7.47 0.37 6.6e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4555082 0.834 rs11622165 chr14:105759761 C/A cg10792982 chr14:105748885 BRF1 0.46 5.94 0.31 7.16e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs798554 0.797 rs1182183 chr7:2873136 C/T cg04166393 chr7:2884313 GNA12 0.46 6.19 0.32 1.76e-9 Height; LIHC cis rs7552167 0.925 rs4489498 chr1:24512055 A/G cg01960748 chr1:24522592 NA 0.59 8.23 0.41 3.98e-15 Psoriasis vulgaris; LIHC cis rs6424115 1.000 rs12031592 chr1:24127864 A/C cg15997130 chr1:24165203 NA 0.42 8.56 0.42 3.86e-16 Immature fraction of reticulocytes; LIHC cis rs2832191 0.740 rs2012645 chr21:30445961 G/A cg24692254 chr21:30365293 RNF160 0.87 15.64 0.65 5.61e-42 Dental caries; LIHC cis rs933688 1.000 rs10041402 chr5:90738948 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.86 18.23 0.7 2.43e-52 Smoking behavior; LIHC cis rs651907 0.535 rs58658478 chr3:101511667 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.63 9.83 0.47 3.1e-20 Colorectal cancer; LIHC cis rs6942756 1.000 rs6467243 chr7:129001508 A/G cg02491457 chr7:128862824 NA -0.63 -9.31 -0.45 1.54e-18 White matter hyperintensity burden; LIHC cis rs2439831 0.867 rs45585139 chr15:43700427 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.67 7.82 0.39 6.81e-14 Lung cancer in ever smokers; LIHC cis rs9916302 0.904 rs12452509 chr17:37574722 G/A cg03013999 chr17:37608204 MED1 0.35 5.8 0.3 1.49e-8 Glomerular filtration rate (creatinine); LIHC cis rs4665809 0.938 rs4665822 chr2:26312555 C/G cg04944784 chr2:26401820 FAM59B -0.65 -8.29 -0.41 2.58e-15 Gut microbiome composition (summer); LIHC cis rs703842 0.963 rs2291617 chr12:58166403 T/G cg04478727 chr12:58166393 METTL1;FAM119B 0.85 13.96 0.6 2.33e-35 Multiple sclerosis; LIHC cis rs4423214 0.840 rs1792227 chr11:71177412 A/G cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC trans rs875971 0.929 rs6970860 chr7:65976634 A/G cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.12e-10 Aortic root size; LIHC cis rs2404602 1.000 rs11072603 chr15:76881138 G/T cg03037974 chr15:76606532 NA 0.71 13.6 0.59 5.9e-34 Blood metabolite levels; LIHC cis rs10847980 0.590 rs75217947 chr12:123346177 G/C cg18912006 chr12:123335444 HIP1R 0.76 7.68 0.38 1.67e-13 Adiponectin levels; LIHC cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg05564831 chr3:52568323 NT5DC2 0.34 5.81 0.3 1.47e-8 Bipolar disorder; LIHC cis rs8114671 0.967 rs6088734 chr20:33745046 A/T cg07148914 chr20:33460835 GGT7 0.43 6.04 0.31 4.06e-9 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20087917 chr14:77924039 C14orf133;AHSA1 0.44 6.77 0.34 5.56e-11 Pancreatic cancer; LIHC cis rs2635047 1.000 rs2684818 chr18:44712965 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.48 6.62 0.34 1.39e-10 Educational attainment; LIHC cis rs9896052 0.614 rs9892171 chr17:73452529 C/T cg25649188 chr17:73499917 CASKIN2 0.46 6.91 0.35 2.34e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs11971779 0.680 rs9683 chr7:139107739 T/A cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs4423214 0.559 rs7949129 chr11:71193135 G/C cg05163923 chr11:71159392 DHCR7 -0.58 -7.15 -0.36 5.23e-12 Vitamin D levels; LIHC cis rs1707322 0.721 rs10789471 chr1:46215619 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs7772486 0.790 rs2249386 chr6:146186611 G/A cg05347473 chr6:146136440 FBXO30 0.38 6.08 0.31 3.16e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg08888203 chr3:10149979 C3orf24 0.57 6.49 0.33 3.06e-10 Alzheimer's disease; LIHC cis rs2851682 0.908 rs2727265 chr11:61609004 C/A cg27386326 chr11:61587980 NA 0.57 8.21 0.41 4.67e-15 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs4908768 0.539 rs6670508 chr1:8647917 G/C cg20416874 chr1:8611966 RERE -0.65 -12.06 -0.55 3.77e-28 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06667416 chr3:186501294 EIF4A2;SNORD2 0.43 6.22 0.32 1.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.811 rs2921718 chr2:61795267 C/A cg14146966 chr2:61757674 XPO1 0.48 8.39 0.41 1.32e-15 Tuberculosis; LIHC cis rs1059312 0.771 rs11059922 chr12:129290418 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.77 -16.69 -0.67 3.8e-46 Systemic lupus erythematosus; LIHC cis rs12594515 1.000 rs12594515 chr15:45985071 C/G cg01629716 chr15:45996671 NA -0.54 -9.78 -0.47 4.31e-20 Waist circumference;Weight; LIHC cis rs7789940 0.904 rs6953281 chr7:75946943 C/T cg10167463 chr7:75959203 YWHAG -0.45 -6.98 -0.35 1.56e-11 Multiple sclerosis; LIHC cis rs7716219 0.638 rs1559213 chr5:54870190 A/C cg14753740 chr5:54468940 CDC20B;MIR449C 0.54 7.38 0.37 1.24e-12 Height; LIHC cis rs7923452 0.641 rs928055 chr10:30731146 G/A cg25182066 chr10:30743637 MAP3K8 0.38 5.8 0.3 1.55e-8 Itch intensity from mosquito bite; LIHC cis rs11031096 0.678 rs17284356 chr11:4189232 G/C cg18678763 chr11:4115507 RRM1 -0.41 -5.95 -0.31 6.62e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs27434 0.607 rs26654 chr5:96140367 C/T cg16492584 chr5:96139282 ERAP1 -0.34 -6.38 -0.33 5.59e-10 Ankylosing spondylitis; LIHC cis rs763121 0.853 rs8140617 chr22:38970439 A/G cg06022373 chr22:39101656 GTPBP1 -0.66 -11.34 -0.52 1.59e-25 Menopause (age at onset); LIHC cis rs1029738 0.500 rs6972589 chr7:22883467 A/G cg11367502 chr7:22862612 TOMM7 -0.35 -5.82 -0.3 1.34e-8 Fibrinogen levels; LIHC cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg13047869 chr3:10149882 C3orf24 0.55 6.53 0.33 2.43e-10 Alzheimer's disease; LIHC cis rs7129220 0.512 rs2119991 chr11:10226268 A/G cg01453529 chr11:10209919 SBF2 -0.43 -7.88 -0.39 4.45e-14 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs265548 0.538 rs36688 chr19:17911212 A/C cg16024904 chr19:17905718 B3GNT3 0.44 6.3 0.32 9.21e-10 Tumor biomarkers; LIHC trans rs875971 1.000 rs6956179 chr7:65806659 C/T cg10756647 chr7:56101905 PSPH -0.44 -6.37 -0.33 6.05e-10 Aortic root size; LIHC cis rs9355610 0.892 rs2247314 chr6:167370230 T/C cg23791538 chr6:167370224 RNASET2 0.78 14.43 0.62 3.44e-37 Graves' disease; LIHC cis rs2797160 1.000 rs1739376 chr6:126012084 C/G cg05901451 chr6:126070800 HEY2 0.39 6.61 0.34 1.49e-10 Endometrial cancer; LIHC cis rs12431939 1.000 rs7148508 chr14:51635137 G/A cg23942311 chr14:51606299 NA -0.35 -5.78 -0.3 1.71e-8 Cancer; LIHC cis rs8103278 1.000 rs35302007 chr19:46219145 G/C cg14061069 chr19:46274453 DMPK -0.56 -8.79 -0.43 7.65e-17 Coronary artery disease; LIHC cis rs6060717 0.654 rs8122716 chr20:34607001 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.46 -7.57 -0.38 3.41e-13 Hip circumference adjusted for BMI; LIHC cis rs7552404 1.000 rs7533888 chr1:76160449 A/C cg22875332 chr1:76189707 ACADM 0.48 7.1 0.36 7.4e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1568889 1.000 rs16917689 chr11:28064466 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.81 0.35 4.36e-11 Bipolar disorder; LIHC cis rs9858542 1.000 rs9836291 chr3:49697459 G/A cg03060546 chr3:49711283 APEH -0.65 -8.74 -0.43 1.09e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg09323728 chr8:95962352 TP53INP1 -0.32 -6.82 -0.35 4.17e-11 Type 2 diabetes; LIHC cis rs17685 0.625 rs1639630 chr7:75730499 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.17 -0.32 1.97e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03651904 chr19:2807229 THOP1 0.43 6.12 0.31 2.57e-9 Longevity; LIHC cis rs4073582 0.595 rs708472 chr11:65930990 A/G cg14036092 chr11:66035641 RAB1B 0.41 6.01 0.31 4.67e-9 Gout; LIHC cis rs4788570 0.697 rs4788443 chr16:71805160 G/A cg06353428 chr16:71660113 MARVELD3 1.33 13.58 0.59 6.87e-34 Intelligence (multi-trait analysis); LIHC cis rs2455799 0.613 rs13080234 chr3:15852492 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.5 -0.38 5.71e-13 Mean platelet volume; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.643 rs596076 chr2:219451015 T/G cg18887096 chr2:219472410 PLCD4 0.37 6.41 0.33 4.9e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs826838 0.585 rs4363678 chr12:38624514 G/A cg26384229 chr12:38710491 ALG10B 0.42 6.35 0.32 6.66e-10 Heart rate; LIHC cis rs9916302 0.821 rs1966915 chr17:37425262 A/C cg00129232 chr17:37814104 STARD3 -0.39 -6.33 -0.32 7.5e-10 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.956 rs55816191 chr11:68262979 G/T cg16797656 chr11:68205561 LRP5 0.55 9.09 0.44 8.22e-18 Total body bone mineral density; LIHC trans rs877282 0.947 rs7923867 chr10:768094 G/A cg22713356 chr15:30763199 NA 1.38 12.35 0.56 3.16e-29 Uric acid levels; LIHC cis rs6546550 0.935 rs3214007 chr2:70098808 A/G cg02498382 chr2:70120550 SNRNP27 -0.4 -6.65 -0.34 1.15e-10 Prevalent atrial fibrillation; LIHC cis rs6088590 1.000 rs6120748 chr20:33458284 T/G cg06115741 chr20:33292138 TP53INP2 0.57 7.72 0.39 1.32e-13 Coronary artery disease; LIHC cis rs2599510 0.783 rs2710630 chr2:32765997 A/C cg02381751 chr2:32503542 YIPF4 -0.43 -5.81 -0.3 1.4e-8 Interleukin-18 levels; LIHC cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg03396347 chr1:1875803 NA 0.47 8.73 0.43 1.17e-16 Body mass index; LIHC cis rs2153535 0.580 rs6941771 chr6:8494452 T/G cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs1664789 1.000 rs1664785 chr5:53281502 T/C ch.5.1024479R chr5:53302184 ARL15 0.53 8.68 0.42 1.61e-16 Waist circumference adjusted for body mass index; LIHC cis rs8060686 0.516 rs73612297 chr16:68284754 T/G cg09835421 chr16:68378352 PRMT7 -0.47 -5.76 -0.3 1.86e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs875971 0.508 rs10253883 chr7:66061138 T/C cg11764359 chr7:65958608 NA -0.63 -9.52 -0.46 3.25e-19 Aortic root size; LIHC cis rs13191362 0.938 rs35211042 chr6:162998703 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.6 5.79 0.3 1.61e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6952808 1.000 rs12699404 chr7:1894022 A/T cg04267008 chr7:1944627 MAD1L1 -0.64 -9.73 -0.47 6.76e-20 Bipolar disorder and schizophrenia; LIHC cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg12373951 chr3:133503437 NA 0.77 14.01 0.6 1.46e-35 Iron status biomarkers; LIHC cis rs6952808 0.771 rs10269191 chr7:1915731 A/G cg03354898 chr7:1950403 MAD1L1 -0.37 -5.71 -0.3 2.41e-8 Bipolar disorder and schizophrenia; LIHC cis rs9467773 1.000 rs6940188 chr6:26562029 G/C cg11502198 chr6:26597334 ABT1 0.44 6.47 0.33 3.46e-10 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg18404041 chr3:52824283 ITIH1 -0.55 -8.85 -0.43 4.73e-17 Bipolar disorder; LIHC cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg05368731 chr17:41323189 NBR1 0.73 12.52 0.56 7.27e-30 Menopause (age at onset); LIHC trans rs1814175 0.645 rs7119101 chr11:49955665 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.4 0.41 1.19e-15 Platelet count; LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg13126279 chr21:47581558 C21orf56 0.41 6.5 0.33 2.84e-10 Testicular germ cell tumor; LIHC cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg12310025 chr6:25882481 NA -0.48 -7.31 -0.37 1.93e-12 Height; LIHC cis rs10751667 0.714 rs7933889 chr11:972270 C/T cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs992157 0.835 rs12987219 chr2:219144149 G/A cg00012203 chr2:219082015 ARPC2 -0.82 -13.08 -0.58 5.58e-32 Colorectal cancer; LIHC cis rs2153535 0.580 rs6937186 chr6:8494493 A/C cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs2797160 1.000 rs2211419 chr6:125995533 C/T cg05901451 chr6:126070800 HEY2 0.41 6.84 0.35 3.69e-11 Endometrial cancer; LIHC cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs2455826 0.544 rs2470517 chr3:15759360 T/A cg12698662 chr3:15914712 MIR563 -0.41 -5.72 -0.3 2.38e-8 Inflammatory skin disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03834947 chr15:65321822 MTFMT -0.44 -6.31 -0.32 8.52e-10 Pancreatic cancer; LIHC cis rs67981189 0.574 rs4467005 chr14:71498656 C/T cg15816911 chr14:71606274 NA 0.43 6.9 0.35 2.57e-11 Schizophrenia; LIHC cis rs1003719 0.788 rs60447195 chr21:38448600 A/T cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs8017423 0.935 rs2149653 chr14:90669333 G/A cg14092571 chr14:90743983 NA -0.36 -5.74 -0.3 2.14e-8 Mortality in heart failure; LIHC cis rs2153535 0.580 rs965706 chr6:8464708 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs6456156 0.586 rs911632 chr6:167471461 T/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.69 -0.43 1.56e-16 Primary biliary cholangitis; LIHC cis rs6120849 0.754 rs7268266 chr20:33581889 T/C cg24642439 chr20:33292090 TP53INP2 0.64 7.07 0.36 8.93e-12 Protein C levels; LIHC trans rs2243480 1.000 rs35391607 chr7:65360829 G/A cg10756647 chr7:56101905 PSPH 1.09 13.38 0.59 4.07e-33 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24511898 chr2:242576823 ATG4B;THAP4 0.44 6.89 0.35 2.7e-11 Pancreatic cancer; LIHC cis rs11212260 0.655 rs11212231 chr11:107306200 C/G cg25435332 chr11:107328525 CWF19L2 0.84 8.08 0.4 1.15e-14 IgG glycosylation; LIHC cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg14393609 chr7:65229607 NA 0.45 6.67 0.34 1.02e-10 Aortic root size; LIHC cis rs11166927 0.548 rs4736099 chr8:140828745 T/C cg16909799 chr8:140841666 TRAPPC9 -0.47 -7.47 -0.37 6.6e-13 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs7582180 0.764 rs11682748 chr2:100925934 C/A cg14675211 chr2:100938903 LONRF2 0.51 8.02 0.4 1.72e-14 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.579 rs11011461 chr10:38431427 G/A cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs936229 0.813 rs7085 chr15:75095483 T/C cg14664628 chr15:75095509 CSK -1.03 -21.18 -0.75 3.36e-64 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs6964587 0.626 rs2188841 chr7:91522641 A/G cg17063962 chr7:91808500 NA -0.62 -11.18 -0.52 6.12e-25 Breast cancer; LIHC cis rs2180341 1.000 rs6569483 chr6:127658855 G/A cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC trans rs9956878 0.555 rs8085188 chr18:73544676 A/G cg03925425 chr13:111768023 ARHGEF7 -0.41 -6.12 -0.31 2.6e-9 Obesity-related traits; LIHC cis rs12908161 1.000 rs11638290 chr15:85227636 C/T cg17507749 chr15:85114479 UBE2QP1 0.66 7.57 0.38 3.48e-13 Schizophrenia; LIHC cis rs10751667 0.621 rs10794351 chr11:946228 C/T cg10932868 chr11:921992 NA 0.4 7.54 0.38 4.38e-13 Alzheimer's disease (late onset); LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg01818776 chr8:25202910 DOCK5 0.37 6.36 0.33 6.43e-10 Monocyte count; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg09875780 chr16:89357086 ANKRD11 0.44 6.14 0.32 2.34e-9 Lung function (FEV1); LIHC cis rs2075371 0.830 rs1421478 chr7:133922793 T/A cg11752832 chr7:134001865 SLC35B4 0.48 6.13 0.31 2.42e-9 Mean platelet volume; LIHC cis rs832540 0.669 rs832538 chr5:56200016 C/T cg24531977 chr5:56204891 C5orf35 -0.49 -7.11 -0.36 6.62e-12 Coronary artery disease; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg05315874 chr8:20054693 ATP6V1B2 -0.6 -6.16 -0.32 2.03e-9 Obesity-related traits; LIHC cis rs990171 0.506 rs9284725 chr2:102744854 C/A cg22835712 chr2:102737379 NA 0.57 8.79 0.43 7.18e-17 Lymphocyte counts; LIHC trans rs1814175 0.530 rs11040482 chr11:49727068 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.78 0.34 5.32e-11 Height; LIHC cis rs35110281 0.712 rs1454648 chr21:45053815 C/T cg21573476 chr21:45109991 RRP1B -0.57 -10.73 -0.5 2.48e-23 Mean corpuscular volume; LIHC cis rs796364 1.000 rs1509835 chr2:200814809 C/G cg23649088 chr2:200775458 C2orf69 0.47 5.82 0.3 1.36e-8 Schizophrenia; LIHC cis rs2070488 0.965 rs13097628 chr3:38521156 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.95 0.65 3.35e-43 Electrocardiographic conduction measures; LIHC trans rs2243480 0.708 rs13242216 chr7:65898277 T/C cg10756647 chr7:56101905 PSPH 1.0 11.41 0.53 8.84e-26 Diabetic kidney disease; LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg11494091 chr17:61959527 GH2 0.36 6.1 0.31 2.95e-9 Height; LIHC cis rs6964587 0.610 rs10953056 chr7:91466700 C/T cg17063962 chr7:91808500 NA 0.62 10.72 0.5 2.7e-23 Breast cancer; LIHC cis rs9896933 0.775 rs615630 chr17:80730527 T/C cg20578329 chr17:80767326 TBCD 0.74 7.38 0.37 1.19e-12 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC trans rs2243480 1.000 rs1796220 chr7:66062100 C/T cg10756647 chr7:56101905 PSPH 1.01 11.98 0.54 7.24e-28 Diabetic kidney disease; LIHC cis rs10504073 0.647 rs12546839 chr8:50009020 C/T cg00325661 chr8:49890786 NA 0.32 7.21 0.36 3.6e-12 Blood metabolite ratios; LIHC cis rs11785400 1.000 rs4518642 chr8:143737396 T/C cg24634471 chr8:143751801 JRK 0.51 8.18 0.4 5.61e-15 Schizophrenia; LIHC cis rs40363 0.645 rs250633 chr16:3523002 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.44 -6.59 -0.34 1.64e-10 Tuberculosis; LIHC cis rs965469 0.652 rs6051837 chr20:3388994 G/T cg25506879 chr20:3388711 C20orf194 -0.53 -7.1 -0.36 7.24e-12 IFN-related cytopenia; LIHC cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.54 7.03 0.36 1.14e-11 Osteoporosis; LIHC cis rs11229555 0.645 rs12794534 chr11:58179568 C/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9902453 0.808 rs4595850 chr17:28206326 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.03e-27 Coffee consumption (cups per day); LIHC cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg04317338 chr11:64019027 PLCB3 0.5 7.01 0.35 1.31e-11 Platelet count; LIHC trans rs6582630 0.621 rs10880656 chr12:38571220 A/C cg05848834 chr11:43543746 NA -0.3 -6.26 -0.32 1.13e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg10774155 chr7:65338427 VKORC1L1 -0.43 -6.41 -0.33 4.94e-10 Calcium levels; LIHC cis rs425277 0.539 rs3128338 chr1:2046786 G/A cg04315214 chr1:2043799 PRKCZ 0.46 7.24 0.36 3.03e-12 Height; LIHC cis rs7552404 0.691 rs5745449 chr1:76344711 A/T cg10523679 chr1:76189770 ACADM -0.55 -6.44 -0.33 3.94e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2176862 1.000 rs114992459 chr3:46611799 C/A cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.34 -0.32 7.42e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs11971779 0.715 rs6467854 chr7:139127083 A/G cg07862535 chr7:139043722 LUC7L2 0.59 9.92 0.47 1.46e-20 Diisocyanate-induced asthma; LIHC cis rs4595586 0.525 rs1400279 chr12:39343825 T/A cg26384229 chr12:38710491 ALG10B 0.53 6.35 0.32 6.99e-10 Morning vs. evening chronotype; LIHC cis rs66569888 0.789 rs17213078 chr2:106734065 G/A cg15412446 chr2:106886593 NA -0.69 -6.87 -0.35 3.07e-11 Facial morphology (factor 23); LIHC cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg21782813 chr7:2030301 MAD1L1 0.43 7.08 0.36 8.38e-12 Bipolar disorder and schizophrenia; LIHC cis rs17376456 1.000 rs13174700 chr5:93554644 G/A cg25358565 chr5:93447407 FAM172A 1.08 9.8 0.47 3.72e-20 Diabetic retinopathy; LIHC cis rs875971 0.929 rs778712 chr7:65849978 C/T cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs2286885 1.000 rs2286885 chr9:129246487 A/C cg15282417 chr9:129245246 FAM125B 0.41 6.58 0.34 1.78e-10 Intraocular pressure; LIHC cis rs148734725 1 rs148734725 chr3:49406708 G/A cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Educational attainment (college completion); LIHC cis rs317689 0.600 rs478188 chr12:69639215 A/G cg20891283 chr12:69753455 YEATS4 0.47 6.52 0.33 2.49e-10 Response to diuretic therapy; LIHC cis rs11673344 0.711 rs112857724 chr19:37521078 G/T cg27390819 chr19:37464633 NA -0.49 -5.97 -0.31 6.08e-9 Obesity-related traits; LIHC cis rs332507 0.830 rs3772786 chr3:124395250 A/C cg05980111 chr3:124395277 KALRN 0.46 7.02 0.35 1.22e-11 Plateletcrit; LIHC cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.29 -0.32 9.43e-10 Tonsillectomy; LIHC cis rs709400 1.000 rs58133129 chr14:104104759 A/G cg26031613 chr14:104095156 KLC1 1.06 14.08 0.61 7.86e-36 Body mass index; LIHC cis rs77637988 0.604 rs78597273 chr2:48607804 G/A cg15846641 chr2:48541264 FOXN2 0.57 7.51 0.38 5.34e-13 Joint mobility (Beighton score); LIHC cis rs35883536 0.626 rs7536054 chr1:101047849 A/G cg14515779 chr1:101123966 NA 0.49 6.76 0.34 6e-11 Monocyte count; LIHC cis rs9326778 0.520 rs4348263 chr5:108845690 C/T cg17395555 chr5:108820864 NA -0.37 -6.26 -0.32 1.12e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs921968 0.541 rs2556391 chr2:219556346 T/C cg02176678 chr2:219576539 TTLL4 -0.53 -7.04 -0.36 1.08e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs11792861 0.855 rs116127510 chr9:111868344 G/A cg13535736 chr9:111863775 C9orf5 -0.38 -5.73 -0.3 2.21e-8 Menarche (age at onset); LIHC cis rs7312774 0.618 rs11612483 chr12:107346884 A/G cg16260113 chr12:107380972 MTERFD3 0.85 11.13 0.52 9.19e-25 Severe influenza A (H1N1) infection; LIHC cis rs1552244 0.572 rs6797536 chr3:10168802 C/T cg00149659 chr3:10157352 C3orf10 -1.11 -10.29 -0.49 8.37e-22 Alzheimer's disease; LIHC cis rs11640734 0.609 rs11647746 chr16:89806343 C/A cg19635926 chr16:89946313 TCF25 0.46 5.89 0.3 9.29e-9 Interleukin-17 levels; LIHC cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.3 -0.45 1.77e-18 Bipolar disorder; LIHC cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.88 13.75 0.6 1.51e-34 Alzheimer's disease; LIHC trans rs3858145 0.588 rs55888445 chr10:70036456 C/T cg04882175 chr6:131122610 NA -0.48 -6.05 -0.31 3.7e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs2370759 1.000 rs78959390 chr10:32616346 C/T cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs2019960 0.759 rs2608025 chr8:129173122 A/G cg15331705 chr8:129180010 NA -0.36 -6.61 -0.34 1.52e-10 Hodgkin's lymphoma;Multiple sclerosis; LIHC cis rs13392177 0.543 rs12623716 chr2:219073018 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.54 -7.57 -0.38 3.57e-13 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs477895 0.713 rs7952318 chr11:63961242 G/A cg18225595 chr11:63971243 STIP1 0.67 8.52 0.42 5.23e-16 Mean platelet volume; LIHC cis rs3796619 0.961 rs62294748 chr4:1082999 G/A cg27284194 chr4:1044797 NA 0.62 10.4 0.49 3.36e-22 Recombination rate (males); LIHC cis rs11122272 0.735 rs2491404 chr1:231512127 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs9381040 0.674 rs4711657 chr6:41162715 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.37 -5.89 -0.3 9.12e-9 Alzheimer's disease (late onset); LIHC cis rs12188164 0.525 rs2561665 chr5:460135 A/G cg24955955 chr5:415729 AHRR 0.32 6.47 0.33 3.33e-10 Cystic fibrosis severity; LIHC cis rs1580019 0.961 rs11765387 chr7:32494790 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26059219 chr3:4508837 SUMF1 0.42 6.15 0.32 2.13e-9 Pancreatic cancer; LIHC trans rs7613875 0.537 rs6446195 chr3:50070853 A/G cg21659725 chr3:3221576 CRBN -0.54 -8.13 -0.4 8.15e-15 Body mass index; LIHC cis rs7116495 1.000 rs2250866 chr11:71804513 A/G cg26138937 chr11:71823887 C11orf51 -0.76 -7.68 -0.38 1.7e-13 Severe influenza A (H1N1) infection; LIHC cis rs2832191 0.716 rs8132085 chr21:30501389 G/T cg24692254 chr21:30365293 RNF160 -0.78 -12.44 -0.56 1.52e-29 Dental caries; LIHC cis rs11758351 1.000 rs77961951 chr6:26186075 A/G cg16070018 chr6:26224392 HIST1H3E 0.65 7.79 0.39 7.91e-14 Gout;Renal underexcretion gout; LIHC cis rs8180040 0.620 rs11917361 chr3:47070497 G/T cg27129171 chr3:47204927 SETD2 -0.53 -8.98 -0.44 1.89e-17 Colorectal cancer; LIHC cis rs7635838 0.859 rs6768611 chr3:11434465 G/A cg00170343 chr3:11313890 ATG7 0.48 7.33 0.37 1.66e-12 HDL cholesterol; LIHC cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg00149659 chr3:10157352 C3orf10 0.69 7.28 0.37 2.3e-12 Alzheimer's disease; LIHC cis rs10736390 0.538 rs12410550 chr1:55107306 A/G cg01517571 chr1:55089959 ACOT11;FAM151A -0.69 -12.06 -0.55 3.93e-28 Survival in pancreatic cancer; LIHC cis rs2816062 0.786 rs2816059 chr1:18902977 G/A cg18795169 chr1:18902165 NA -0.79 -17.25 -0.68 1.97e-48 Urate levels in lean individuals; LIHC cis rs3806843 0.900 rs2563280 chr5:140131530 G/C cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7208859 0.673 rs11651802 chr17:29159660 T/C cg14067834 chr17:29058358 SUZ12P 0.68 6.61 0.34 1.46e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs1003719 0.762 rs1155786 chr21:38448025 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.76 11.83 0.54 2.59e-27 Eye color traits; LIHC cis rs12413816 0.824 rs1571008 chr10:13760776 T/C cg16485048 chr10:13749193 FRMD4A 0.58 8.67 0.42 1.8e-16 Red cell distribution width; LIHC cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg25894440 chr7:65020034 NA -0.54 -6.27 -0.32 1.08e-9 Diabetic kidney disease; LIHC cis rs8020095 0.528 rs6573760 chr14:67677375 G/T cg03487553 chr14:67822707 ATP6V1D -0.34 -5.75 -0.3 1.93e-8 Depression (quantitative trait); LIHC cis rs12368653 0.525 rs1564374 chr12:58010163 C/T cg12615879 chr12:58013172 SLC26A10 0.34 6.73 0.34 7.29e-11 Multiple sclerosis; LIHC cis rs9534288 0.912 rs9534297 chr13:46624630 T/C cg15192986 chr13:46630673 CPB2 -0.57 -8.61 -0.42 2.76e-16 Blood protein levels; LIHC cis rs796364 0.806 rs10931887 chr2:200968905 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.65 -7.22 -0.36 3.35e-12 Schizophrenia; LIHC cis rs4820539 1.000 rs6003518 chr22:23471533 C/T cg21100191 chr22:23484243 RTDR1 0.91 16.72 0.67 2.75e-46 Bone mineral density; LIHC cis rs910316 0.737 rs108621 chr14:75480637 T/C cg08847533 chr14:75593920 NEK9 -0.86 -17.37 -0.68 7.01e-49 Height; LIHC cis rs2115630 0.691 rs2292462 chr15:85200754 G/T cg11189052 chr15:85197271 WDR73 -0.51 -7.77 -0.39 9.16e-14 P wave terminal force; LIHC cis rs9611565 0.729 rs137831 chr22:41903813 A/C cg03806693 chr22:41940476 POLR3H -0.57 -7.44 -0.37 7.96e-13 Vitiligo; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00154443 chr16:71917454 ATXN1L;ZNF821 0.45 6.08 0.31 3.29e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11608355 0.545 rs11613023 chr12:109898047 T/C cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs10256972 0.626 rs62433138 chr7:1050877 T/C cg23978390 chr7:1156363 C7orf50 0.43 6.19 0.32 1.74e-9 Longevity;Endometriosis; LIHC cis rs147858478 1 rs147858478 chr5:131682785 CCTGAGTT/C cg24060327 chr5:131705240 SLC22A5 -0.57 -8.17 -0.4 6.13e-15 High light scatter reticulocyte percentage of red cells; LIHC trans rs7618501 0.966 rs13063621 chr3:49821625 T/C cg21582582 chr3:182698605 DCUN1D1 0.52 6.77 0.34 5.48e-11 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.580 rs960212 chr3:161047974 C/T cg03342759 chr3:160939853 NMD3 -0.44 -6.32 -0.32 8.28e-10 Morning vs. evening chronotype; LIHC cis rs4789452 0.716 rs1105410 chr17:75383942 C/T cg06761530 chr17:75373219 SEPT9 -0.46 -5.99 -0.31 5.31e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC trans rs2243480 1.000 rs160646 chr7:65556280 C/T cg10756647 chr7:56101905 PSPH 1.07 13.46 0.59 1.91e-33 Diabetic kidney disease; LIHC cis rs7552404 0.924 rs7535991 chr1:76162624 C/T cg22875332 chr1:76189707 ACADM 0.48 7.45 0.37 7.7e-13 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2681424 1.000 rs2681424 chr3:121769522 T/C cg03946530 chr15:65596423 NA 0.49 6.2 0.32 1.65e-9 Multiple sclerosis; LIHC cis rs1055129 0.682 rs7217432 chr17:73834604 A/G cg08125733 chr17:73851984 WBP2 0.5 8.12 0.4 8.52e-15 White matter hyperintensity burden; LIHC cis rs8064024 0.604 rs1049212 chr16:4932929 A/G cg08329684 chr16:4932620 PPL -0.44 -7.79 -0.39 7.92e-14 Cancer; LIHC cis rs2404602 0.574 rs4886795 chr15:76642218 G/C cg06336613 chr15:77223807 RCN2 0.41 5.92 0.31 7.71e-9 Blood metabolite levels; LIHC cis rs6988636 1.000 rs13260318 chr8:124190165 C/G cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs8180040 0.726 rs13094672 chr3:47149439 C/T cg27129171 chr3:47204927 SETD2 0.68 11.78 0.54 4.19e-27 Colorectal cancer; LIHC cis rs1144333 0.850 rs1146651 chr1:76273594 C/A cg03433033 chr1:76189801 ACADM -0.56 -8.58 -0.42 3.33e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs7395581 0.918 rs4752824 chr11:47324666 A/T cg25783544 chr11:47291846 MADD 0.39 5.75 0.3 1.96e-8 HDL cholesterol; LIHC cis rs11122272 0.735 rs2572253 chr1:231512768 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.69 -0.5 3.38e-23 Hemoglobin concentration; LIHC trans rs6951245 0.706 rs28483034 chr7:1170171 C/A cg13565492 chr6:43139072 SRF -0.78 -6.63 -0.34 1.28e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26367235 chr2:239997305 HDAC4 -0.4 -6.3 -0.32 9.2e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg13866156 chr1:1669148 SLC35E2 -0.7 -13.74 -0.6 1.67e-34 Body mass index; LIHC cis rs7903847 0.642 rs7088410 chr10:99135539 G/T cg06359132 chr10:99160096 RRP12 -0.42 -6.6 -0.34 1.57e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7091068 0.616 rs1890657 chr10:95506087 G/A cg20715218 chr10:95462985 C10orf4 0.58 6.05 0.31 3.9e-9 Urinary tract infection frequency; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15827486 chr2:98262568 COX5B -0.39 -6.12 -0.31 2.62e-9 Cognitive function; LIHC cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg21724239 chr8:58056113 NA 0.58 7.51 0.38 5.35e-13 Developmental language disorder (linguistic errors); LIHC cis rs4908768 0.906 rs12122851 chr1:8634290 A/G cg25722041 chr1:8623473 RERE -0.41 -6.09 -0.31 3.09e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7412746 0.658 rs7528773 chr1:150915875 G/A cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg23758822 chr17:41437982 NA 0.94 17.84 0.69 8.48e-51 Menopause (age at onset); LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg26338869 chr17:61819248 STRADA 0.53 7.14 0.36 5.49e-12 Height; LIHC cis rs35306767 0.953 rs12259801 chr10:959306 C/G cg26597838 chr10:835615 NA 0.98 11.98 0.54 7.58e-28 Eosinophil percentage of granulocytes; LIHC cis rs11053548 0.614 rs11053555 chr12:10175993 G/A cg04314261 chr12:10163030 CLEC12B 0.38 5.91 0.3 8.29e-9 Systolic blood pressure in sickle cell anemia; LIHC cis rs61990749 0.597 rs8016447 chr14:78222068 C/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.79 -0.39 8.05e-14 Fibroblast growth factor basic levels; LIHC cis rs2050392 0.630 rs303426 chr10:30740379 A/G cg25182066 chr10:30743637 MAP3K8 0.54 8.56 0.42 3.99e-16 Inflammatory bowel disease; LIHC cis rs9911578 1.000 rs9898916 chr17:57048660 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -8.76 -0.43 8.95e-17 Intelligence (multi-trait analysis); LIHC cis rs11761441 0.669 rs13241486 chr7:79536 G/C cg13828236 chr7:80970 NA 0.34 8.33 0.41 2.01e-15 Alzheimer's disease in APOE e4- carriers; LIHC cis rs12586317 0.620 rs76293361 chr14:35570889 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.19 0.58 2.12e-32 Psoriasis; LIHC cis rs4474465 0.850 rs7111004 chr11:78269961 G/A cg02023728 chr11:77925099 USP35 -0.33 -5.92 -0.3 8.01e-9 Alzheimer's disease (survival time); LIHC cis rs11190604 1.000 rs2273694 chr10:102256496 G/T cg07080220 chr10:102295463 HIF1AN 0.57 8.65 0.42 2e-16 Palmitoleic acid (16:1n-7) levels; LIHC cis rs754466 1.000 rs67059283 chr10:79683235 C/T cg17075019 chr10:79541650 NA -0.63 -8.49 -0.42 6.43e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7666738 0.609 rs35214820 chr4:98864692 G/A cg05340658 chr4:99064831 C4orf37 0.5 6.54 0.33 2.18e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7937890 0.900 rs7118682 chr11:14274550 T/G cg19336497 chr11:14380999 RRAS2 0.34 5.75 0.3 1.95e-8 Mitochondrial DNA levels; LIHC cis rs644799 1.000 rs544119 chr11:95538624 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs765787 0.530 rs1648287 chr15:45516956 T/C cg24006582 chr15:45444508 DUOX1 -0.55 -7.91 -0.39 3.5e-14 Uric acid levels; LIHC cis rs12701220 0.817 rs1058727 chr7:1087095 A/G cg04025307 chr7:1156635 C7orf50 0.44 5.98 0.31 5.71e-9 Bronchopulmonary dysplasia; LIHC cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg12310025 chr6:25882481 NA 0.87 11.48 0.53 5.01e-26 Blood metabolite levels; LIHC cis rs13191362 0.935 rs13215748 chr6:163010710 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2153535 0.580 rs9406172 chr6:8515464 T/A cg23788917 chr6:8435910 SLC35B3 0.62 8.74 0.43 1.08e-16 Motion sickness; LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.6 0.77 7.76e-70 Height; LIHC cis rs11955398 0.583 rs7719726 chr5:59949537 T/C cg02684056 chr5:59996105 DEPDC1B 0.43 5.98 0.31 5.61e-9 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg13047869 chr3:10149882 C3orf24 0.47 6.02 0.31 4.39e-9 Alzheimer's disease; LIHC cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg10063637 chr16:4524514 NMRAL1;HMOX2 0.42 5.72 0.3 2.35e-8 Schizophrenia; LIHC cis rs2404602 0.647 rs12904417 chr15:76964152 A/G cg23625390 chr15:77176239 SCAPER 0.54 9.08 0.44 8.7e-18 Blood metabolite levels; LIHC cis rs7474896 0.537 rs2749588 chr10:38269457 C/G cg25427524 chr10:38739819 LOC399744 -0.45 -5.94 -0.31 7.07e-9 Obesity (extreme); LIHC cis rs875971 0.862 rs6958294 chr7:65794796 C/A cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs600806 0.713 rs11102984 chr1:109997373 T/C cg11161837 chr1:110010384 SYPL2 0.44 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs66573146 0.831 rs6851488 chr4:6987412 C/T cg15105060 chr4:7024189 TBC1D14 -0.72 -6.36 -0.33 6.34e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12458462 0.859 rs35493271 chr18:77448793 G/T cg11879182 chr18:77439856 CTDP1 0.85 14.78 0.62 1.39e-38 Monocyte count; LIHC cis rs9389248 0.500 rs116273677 chr6:135339135 A/C cg22676075 chr6:135203613 NA 0.39 6.25 0.32 1.24e-9 High light scatter reticulocyte percentage of red cells; LIHC cis rs3815700 1.000 rs8101356 chr19:33093402 C/T cg02997394 chr19:33096574 ANKRD27 0.72 9.25 0.45 2.55e-18 Eosinophilic esophagitis; LIHC cis rs17106184 1.000 rs72902777 chr1:51272278 T/C cg07174182 chr1:51127561 FAF1 -0.65 -6.99 -0.35 1.46e-11 Type 2 diabetes; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.66 0.38 1.89e-13 Prudent dietary pattern; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs2282802 0.685 rs2436391 chr5:139557385 C/T cg26211634 chr5:139558579 C5orf32 -0.39 -6.05 -0.31 3.82e-9 Intelligence (multi-trait analysis); LIHC cis rs13392177 0.672 rs4674270 chr2:219053141 G/T cg20019365 chr2:219134978 PNKD;AAMP -0.54 -7.46 -0.37 7.22e-13 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs3806843 1.000 rs12717860 chr5:140171442 C/T cg26395211 chr5:140044315 WDR55 -0.43 -6.41 -0.33 4.77e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs9733 0.596 rs7418501 chr1:150711896 A/T cg18016565 chr1:150552671 MCL1 0.57 11.59 0.53 1.95e-26 Tonsillectomy; LIHC cis rs61041384 0.661 rs77193970 chr12:123516317 G/A cg25930673 chr12:123319894 HIP1R 0.65 6.14 0.31 2.33e-9 Schizophrenia; LIHC cis rs9381040 0.655 rs2268194 chr6:41024447 T/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.42 -0.33 4.67e-10 Alzheimer's disease (late onset); LIHC cis rs12477438 0.572 rs10170063 chr2:99655639 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs7707921 1.000 rs6884232 chr5:81550043 G/A cg15871215 chr5:81402204 ATG10 0.59 5.86 0.3 1.12e-8 Breast cancer; LIHC cis rs28735056 0.565 rs12957336 chr18:77716889 A/G cg20368463 chr18:77673604 PQLC1 -0.34 -5.77 -0.3 1.78e-8 Schizophrenia; LIHC cis rs7666738 0.716 rs114187620 chr4:98819534 T/A cg05340658 chr4:99064831 C4orf37 0.63 11.49 0.53 4.74e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs270601 0.913 rs273916 chr5:131659830 C/A cg24060327 chr5:131705240 SLC22A5 -0.82 -12.88 -0.57 3.09e-31 Acylcarnitine levels; LIHC cis rs6088580 0.634 rs4911422 chr20:32999345 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg00091569 chr3:40428383 ENTPD3 -0.36 -6.12 -0.31 2.52e-9 Renal cell carcinoma; LIHC cis rs11690935 0.959 rs13419987 chr2:172623914 T/C cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.53 -0.69 1.51e-49 Schizophrenia; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg08677398 chr8:58056175 NA 0.4 5.82 0.3 1.39e-8 Developmental language disorder (linguistic errors); LIHC cis rs2439831 0.850 rs7183809 chr15:44120868 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.7 0.34 8.58e-11 Lung cancer in ever smokers; LIHC cis rs2576037 0.526 rs649076 chr18:44414614 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.52e-12 Personality dimensions; LIHC cis rs911119 0.913 rs13043610 chr20:23586941 G/A cg16589663 chr20:23618590 CST3 0.76 7.87 0.39 4.59e-14 Chronic kidney disease; LIHC cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 8.54 0.42 4.33e-16 Platelet count; LIHC cis rs903552 1.000 rs4965873 chr15:102004023 A/G cg25677261 chr15:102009856 PCSK6 0.46 6.23 0.32 1.37e-9 Diabetic kidney disease; LIHC cis rs611744 0.647 rs4735053 chr8:109260776 A/G cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs929354 0.772 rs6459741 chr7:157014553 G/T cg05182265 chr7:156933206 UBE3C -0.33 -6.3 -0.32 8.96e-10 Body mass index; LIHC cis rs2971970 0.519 rs2346272 chr7:133654830 T/C cg03336402 chr7:133662267 EXOC4 -0.48 -5.76 -0.3 1.91e-8 Intelligence (multi-trait analysis); LIHC cis rs7904368 0.754 rs7076779 chr10:16852667 C/T cg23933602 chr10:16859644 RSU1 0.55 5.78 0.3 1.65e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs4969178 0.965 rs4969186 chr17:76398404 C/G cg20026190 chr17:76395443 PGS1 0.47 7.53 0.38 4.6e-13 HDL cholesterol levels; LIHC cis rs28374715 0.635 rs112547435 chr15:41648737 C/G cg18705301 chr15:41695430 NDUFAF1 -1.04 -15.27 -0.64 1.71e-40 Ulcerative colitis; LIHC cis rs3106136 0.814 rs10020236 chr4:95277993 A/G cg11021082 chr4:95130006 SMARCAD1 0.38 6.56 0.33 2.02e-10 Capecitabine sensitivity; LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg00656387 chr3:40428638 ENTPD3 0.5 8.57 0.42 3.52e-16 Renal cell carcinoma; LIHC cis rs11098499 0.629 rs28369518 chr4:120271630 T/C cg09307838 chr4:120376055 NA 0.62 9.83 0.47 3e-20 Corneal astigmatism; LIHC cis rs10876993 0.890 rs1678516 chr12:58047458 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.52 -0.33 2.54e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs1055129 0.655 rs7216615 chr17:73833910 T/C cg10935138 chr17:73851978 WBP2 0.45 6.94 0.35 1.98e-11 White matter hyperintensity burden; LIHC cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg06453172 chr10:134556979 INPP5A -0.64 -8.19 -0.4 5.32e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs507080 0.663 rs7926970 chr11:118559881 T/G cg04173919 chr11:118528438 PHLDB1 0.35 6.62 0.34 1.42e-10 Serum metabolite levels; LIHC cis rs6912958 0.559 rs445434 chr6:88041849 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.16 0.52 6.89e-25 Monocyte percentage of white cells; LIHC cis rs826838 0.967 rs1719853 chr12:39128515 A/G cg26384229 chr12:38710491 ALG10B -0.6 -8.66 -0.42 1.92e-16 Heart rate; LIHC cis rs9733 0.596 rs12403255 chr1:150660412 C/T cg17724175 chr1:150552817 MCL1 0.49 9.9 0.47 1.7e-20 Tonsillectomy; LIHC cis rs11212260 0.655 rs11212216 chr11:107291251 T/A cg25435332 chr11:107328525 CWF19L2 0.8 8.13 0.4 7.75e-15 IgG glycosylation; LIHC cis rs992157 0.710 rs12694432 chr2:219082330 A/G cg00012203 chr2:219082015 ARPC2 0.92 16.53 0.67 1.54e-45 Colorectal cancer; LIHC cis rs2574704 0.816 rs2443722 chr3:11663732 A/G cg15876825 chr3:11651881 VGLL4 -0.49 -7.38 -0.37 1.21e-12 Body mass index; LIHC cis rs5753618 0.561 rs9606831 chr22:31732512 C/T cg07713946 chr22:31675144 LIMK2 0.41 7.46 0.37 7.26e-13 Colorectal cancer; LIHC cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg24549020 chr5:56110836 MAP3K1 0.5 6.49 0.33 3.09e-10 Initial pursuit acceleration; LIHC cis rs644799 0.710 rs10831433 chr11:95519787 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.31 0.58 7.5e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10791323 0.693 rs10750544 chr11:133718740 A/G cg15485101 chr11:133734466 NA 0.25 5.79 0.3 1.63e-8 Childhood ear infection; LIHC cis rs1799949 0.683 rs55737636 chr17:41264739 C/T cg23758822 chr17:41437982 NA 0.93 17.25 0.68 2.02e-48 Menopause (age at onset); LIHC cis rs8180040 0.764 rs13062022 chr3:47169375 G/A cg16586182 chr3:47516702 SCAP -0.5 -9.13 -0.44 6.21e-18 Colorectal cancer; LIHC trans rs11014306 1.000 rs6482455 chr10:25200457 C/G cg17214381 chr4:188916668 ZFP42 -0.56 -6.13 -0.31 2.42e-9 Metabolite levels (Pyroglutamine); LIHC cis rs801193 0.569 rs881285 chr7:66119420 A/G cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs12744310 1.000 rs12036555 chr1:41777990 T/C cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.94 -0.31 7.07e-9 Colorectal cancer; LIHC cis rs6912958 0.781 rs7742965 chr6:88278196 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25508545 chr19:49467065 FTL 0.43 6.3 0.32 8.9e-10 Pancreatic cancer; LIHC cis rs9393692 0.875 rs2142703 chr6:26289605 A/G cg05868516 chr6:26286170 HIST1H4H 0.39 5.9 0.3 8.83e-9 Educational attainment; LIHC cis rs9311474 0.581 rs13621 chr3:52558133 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 6.1 0.31 2.92e-9 Electroencephalogram traits; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs9858542 0.953 rs6997 chr3:49453834 C/T cg03060546 chr3:49711283 APEH -0.45 -6.25 -0.32 1.2e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.83 8.27 0.41 2.93e-15 Platelet count; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg24450312 chr1:206681158 RASSF5 -0.42 -6.51 -0.33 2.69e-10 Bilirubin levels; LIHC cis rs763121 0.853 rs5750659 chr22:39068789 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs1046896 0.519 rs9900369 chr17:80829807 G/A cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.46 0.37 7.27e-13 Glycated hemoglobin levels; LIHC cis rs807029 0.533 rs3740485 chr10:102750621 C/T cg17130504 chr10:102756923 LZTS2 0.56 7.78 0.39 8.74e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs12286929 0.617 rs11607801 chr11:115077367 A/C cg04055981 chr11:115044050 NA 0.5 7.97 0.4 2.38e-14 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7224314 1.000 rs8070689 chr17:65387405 G/T cg01507342 chr17:65387096 PITPNC1 -0.46 -5.9 -0.3 8.64e-9 Diisocyanate-induced asthma; LIHC cis rs6430585 0.528 rs309165 chr2:136667301 T/C cg07169764 chr2:136633963 MCM6 0.98 15.35 0.64 8.11e-41 Corneal structure; LIHC cis rs11702148 0.505 rs28422170 chr21:34980443 G/C cg14850771 chr21:34775459 IFNGR2 0.45 7.12 0.36 6.58e-12 Mean corpuscular hemoglobin; LIHC cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg07092213 chr7:1199455 ZFAND2A -0.42 -6.16 -0.32 2e-9 Longevity;Endometriosis; LIHC cis rs6840360 0.550 rs4696289 chr4:152621237 C/T cg22705602 chr4:152727874 NA -0.4 -7.13 -0.36 5.92e-12 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg11502198 chr6:26597334 ABT1 0.61 9.71 0.47 7.37e-20 Intelligence (multi-trait analysis); LIHC cis rs1865721 1.000 rs62089508 chr18:73193344 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.17e-13 Intelligence; LIHC cis rs9902453 0.967 rs4294864 chr17:28440138 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.82 0.47 3.22e-20 Coffee consumption (cups per day); LIHC cis rs2404602 0.735 rs2468130 chr15:76796496 T/C cg23625390 chr15:77176239 SCAPER -0.46 -7.55 -0.38 4e-13 Blood metabolite levels; LIHC cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg23758822 chr17:41437982 NA 0.94 17.82 0.69 1.05e-50 Menopause (age at onset); LIHC cis rs929354 0.713 rs3802129 chr7:156965297 G/A cg05182265 chr7:156933206 UBE3C -0.31 -5.86 -0.3 1.07e-8 Body mass index; LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg26354017 chr1:205819088 PM20D1 0.77 11.46 0.53 6.06e-26 Menarche (age at onset); LIHC cis rs7312933 0.558 rs11181507 chr12:42844763 T/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.98 0.4 2.2e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7613875 0.600 rs1138536 chr3:50153356 C/T cg21467203 chr3:49911342 NA -0.5 -9.2 -0.45 3.73e-18 Body mass index; LIHC trans rs1005277 0.579 rs2472183 chr10:38392495 T/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.01 -0.51 2.51e-24 Extrinsic epigenetic age acceleration; LIHC cis rs758324 0.898 rs7725041 chr5:131188503 C/A cg06307176 chr5:131281290 NA 0.4 5.72 0.3 2.36e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs6088590 0.930 rs6087618 chr20:33288407 C/T cg08999081 chr20:33150536 PIGU 0.39 6.1 0.31 2.82e-9 Coronary artery disease; LIHC cis rs12908161 1.000 rs12905057 chr15:85210765 A/G cg17507749 chr15:85114479 UBE2QP1 0.66 7.46 0.37 6.98e-13 Schizophrenia; LIHC cis rs1707322 0.896 rs946528 chr1:46485562 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.61 -0.34 1.45e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6066825 0.644 rs2869669 chr20:47321449 T/C cg18078177 chr20:47281410 PREX1 0.43 7.0 0.35 1.35e-11 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04421424 chr19:57791681 ZNF460 0.46 7.08 0.36 8.39e-12 Cognitive function; LIHC cis rs9309711 0.643 rs10188449 chr2:3480366 T/C cg10845886 chr2:3471009 TTC15 -0.42 -7.85 -0.39 5.27e-14 Neurofibrillary tangles; LIHC cis rs801193 0.569 rs4717315 chr7:66178325 C/T cg18252515 chr7:66147081 NA -0.47 -6.86 -0.35 3.26e-11 Aortic root size; LIHC cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg21951975 chr1:209979733 IRF6 0.4 6.44 0.33 4e-10 Cleft lip with or without cleft palate; LIHC cis rs2932538 0.922 rs12402929 chr1:113072293 G/C cg22162597 chr1:113214053 CAPZA1 0.7 9.27 0.45 2.13e-18 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs4820294 1.000 rs78974622 chr22:38059925 A/C cg26138144 chr22:38071188 LGALS1 0.75 14.01 0.6 1.51e-35 Fat distribution (HIV); LIHC cis rs7395581 0.918 rs1052373 chr11:47354787 A/G cg25783544 chr11:47291846 MADD -0.42 -6.09 -0.31 3.1e-9 HDL cholesterol; LIHC cis rs2737618 0.674 rs2737684 chr1:200092951 C/T cg21825944 chr1:200113062 NR5A2 -0.46 -7.84 -0.39 5.87e-14 Uric acid levels; LIHC cis rs4742903 1.000 rs4742905 chr9:106856972 G/C cg14250997 chr9:106856677 SMC2 0.43 7.37 0.37 1.32e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs12497850 0.931 rs4974079 chr3:48906469 T/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.17 0.36 4.76e-12 Parkinson's disease; LIHC cis rs1005277 0.579 rs2023351 chr10:38378814 A/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs8180040 0.764 rs11718795 chr3:47218727 G/A cg27129171 chr3:47204927 SETD2 0.68 11.91 0.54 1.39e-27 Colorectal cancer; LIHC cis rs9902453 0.904 rs7208579 chr17:28263067 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.97 0.6 2.11e-35 Coffee consumption (cups per day); LIHC cis rs2279817 0.735 rs71644064 chr1:18000044 G/A cg21791023 chr1:18019539 ARHGEF10L -0.68 -8.05 -0.4 1.36e-14 Neuroticism; LIHC cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg16049864 chr8:95962084 TP53INP1 -0.63 -11.87 -0.54 1.88e-27 Type 2 diabetes; LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg25405998 chr7:65216604 CCT6P1 0.44 6.53 0.33 2.41e-10 Calcium levels; LIHC cis rs174601 0.864 rs174545 chr11:61569306 C/G cg07689907 chr11:61582574 FADS1 0.39 5.79 0.3 1.58e-8 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs427394 0.659 rs175594 chr5:6729885 T/G cg10857441 chr5:6722123 POLS -0.38 -6.45 -0.33 3.89e-10 Menopause (age at onset); LIHC cis rs7107174 1.000 rs10899492 chr11:78109810 G/A cg02023728 chr11:77925099 USP35 0.4 7.43 0.37 8.74e-13 Testicular germ cell tumor; LIHC cis rs9733 0.596 rs72702556 chr1:150680115 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs1494950 0.661 rs4698307 chr4:14978435 G/A cg12377275 chr4:15005593 CPEB2 -0.79 -6.71 -0.34 8.25e-11 Political ideology; LIHC cis rs3806843 0.838 rs2262567 chr5:140132134 T/A cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs1005277 0.563 rs2505215 chr10:38481273 A/G cg23533926 chr12:111358616 MYL2 -0.32 -6.12 -0.31 2.61e-9 Extrinsic epigenetic age acceleration; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07772128 chr15:75095447 CSK 0.35 6.2 0.32 1.65e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs780094 0.544 rs780108 chr2:27684957 T/C cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.86 -0.3 1.11e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs7937890 1.000 rs2970335 chr11:14325401 A/C cg19336497 chr11:14380999 RRAS2 -0.38 -6.62 -0.34 1.4e-10 Mitochondrial DNA levels; LIHC cis rs35110281 0.744 rs230645 chr21:44918607 A/G cg01579765 chr21:45077557 HSF2BP 0.32 5.9 0.3 8.91e-9 Mean corpuscular volume; LIHC cis rs2637266 1.000 rs12251543 chr10:78345465 G/A cg18941641 chr10:78392320 NA 0.29 6.22 0.32 1.43e-9 Pulmonary function; LIHC cis rs1385374 1.000 rs1385374 chr12:129300694 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.59 7.37 0.37 1.27e-12 Systemic lupus erythematosus; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06350176 chr11:67375936 NDUFV1 0.4 6.13 0.31 2.43e-9 Longevity; LIHC cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg08219700 chr8:58056026 NA 0.52 6.92 0.35 2.19e-11 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07305506 chr3:152058521 MBNL1;TMEM14E 0.33 6.24 0.32 1.27e-9 Hepatitis; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg23084309 chr19:6280164 MLLT1 -0.51 -6.21 -0.32 1.57e-9 Hepatitis; LIHC cis rs7937890 0.904 rs11023169 chr11:14290985 C/A cg22961513 chr11:14280813 SPON1 0.48 7.41 0.37 1e-12 Mitochondrial DNA levels; LIHC cis rs6570726 0.764 rs9322028 chr6:145895797 G/T cg23711669 chr6:146136114 FBXO30 0.72 12.77 0.57 8.53e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs2070488 0.965 rs1046048 chr3:38524742 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.95 0.65 3.35e-43 Electrocardiographic conduction measures; LIHC cis rs7258465 0.965 rs748609 chr19:18560282 T/C cg10790698 chr19:18539756 SSBP4 -0.35 -7.31 -0.37 1.92e-12 Breast cancer; LIHC trans rs8117834 0.574 rs73076229 chr20:8081430 G/A cg00593689 chr4:53575888 NA 0.38 6.36 0.33 6.66e-10 Chronic kidney disease; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg11636631 chr22:20428109 NA -0.42 -6.14 -0.32 2.23e-9 Migraine with aura; LIHC cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -6.13 -0.31 2.4e-9 Bipolar disorder and schizophrenia; LIHC cis rs116095464 0.558 rs10060089 chr5:205565 G/A cg22496380 chr5:211416 CCDC127 -1.19 -10.49 -0.49 1.66e-22 Breast cancer; LIHC cis rs9816226 0.590 rs869401 chr3:185826546 G/A cg00760338 chr3:185826511 ETV5 0.99 15.72 0.65 2.66e-42 Obesity;Body mass index; LIHC cis rs28735056 0.565 rs2012687 chr18:77711127 G/T cg20368463 chr18:77673604 PQLC1 -0.36 -6.11 -0.31 2.73e-9 Schizophrenia; LIHC cis rs523522 0.923 rs2235217 chr12:120884328 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.51 0.53 3.98e-26 High light scatter reticulocyte count; LIHC cis rs36051895 0.632 rs12001334 chr9:5152604 C/A cg02405213 chr9:5042618 JAK2 -0.68 -12.26 -0.55 7.03e-29 Pediatric autoimmune diseases; LIHC cis rs1555399 0.868 rs7160944 chr14:67983485 G/A cg16224230 chr14:67978224 TMEM229B -0.25 -6.04 -0.31 4.02e-9 Parkinson's disease; LIHC cis rs4819052 0.851 rs2838842 chr21:46669217 C/T cg11663144 chr21:46675770 NA -0.34 -6.38 -0.33 5.67e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg07677032 chr17:61819896 STRADA 0.43 6.32 0.32 8.12e-10 Prudent dietary pattern; LIHC cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.06 0.55 3.67e-28 Alzheimer's disease; LIHC cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs748404 0.697 rs471122 chr15:43558574 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.48 -8.23 -0.41 3.86e-15 Lung cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02546883 chr6:157721111 C6orf35 0.5 6.98 0.35 1.55e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs8044995 0.636 rs12447119 chr16:68297928 G/A cg05110241 chr16:68378359 PRMT7 -0.7 -7.36 -0.37 1.38e-12 Schizophrenia; LIHC cis rs875971 0.862 rs6460279 chr7:65662761 T/C cg11764359 chr7:65958608 NA -0.75 -12.45 -0.56 1.34e-29 Aortic root size; LIHC cis rs9952991 0.941 rs2542150 chr18:12779763 G/C cg23598886 chr18:12777645 NA 0.48 6.51 0.33 2.69e-10 Inflammatory skin disease; LIHC cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg02290350 chr8:58132656 NA 0.38 7.93 0.39 3.13e-14 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.735 rs3765115 chr15:76673716 T/C cg23625390 chr15:77176239 SCAPER -0.48 -8.02 -0.4 1.73e-14 Blood metabolite levels; LIHC cis rs12477438 0.520 rs4402818 chr2:99717608 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.86 14.8 0.62 1.24e-38 Chronic sinus infection; LIHC cis rs4718428 0.672 rs13241598 chr7:66300652 A/G cg12165864 chr7:66369176 NA -0.47 -6.86 -0.35 3.21e-11 Corneal structure; LIHC cis rs2455601 0.744 rs11042133 chr11:8966511 A/C cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -6.28 -0.32 1.02e-9 Schizophrenia; LIHC cis rs12701220 0.803 rs12701432 chr7:1052453 C/T cg26769984 chr7:1090371 C7orf50 0.57 7.18 0.36 4.25e-12 Bronchopulmonary dysplasia; LIHC cis rs3812831 0.695 rs422149 chr13:114931086 T/G cg06611532 chr13:114900021 NA 0.43 7.91 0.39 3.71e-14 Schizophrenia; LIHC cis rs7927592 0.913 rs67005337 chr11:68307758 A/C cg20283391 chr11:68216788 NA -0.52 -7.73 -0.39 1.24e-13 Total body bone mineral density; LIHC cis rs4930103 0.935 rs11042170 chr11:2021625 C/T cg06197492 chr11:2016605 H19 0.39 6.21 0.32 1.51e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs1552244 0.572 rs3894321 chr3:10168892 A/C cg00149659 chr3:10157352 C3orf10 0.89 8.58 0.42 3.41e-16 Alzheimer's disease; LIHC cis rs8062405 0.964 rs78613234 chr16:28839425 T/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.27e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.56 0.8 1.79e-77 Prudent dietary pattern; LIHC cis rs12701220 0.948 rs10275712 chr7:1082918 G/A cg16145915 chr7:1198662 ZFAND2A -0.33 -6.39 -0.33 5.45e-10 Bronchopulmonary dysplasia; LIHC cis rs9818758 0.607 rs67060340 chr3:48915321 C/T cg07636037 chr3:49044803 WDR6 -0.79 -7.76 -0.39 9.98e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1552244 0.751 rs12715665 chr3:10021601 C/T cg08888203 chr3:10149979 C3orf24 0.45 5.88 0.3 9.54e-9 Alzheimer's disease; LIHC cis rs8060686 0.641 rs2285910 chr16:68104422 T/C cg09835421 chr16:68378352 PRMT7 -0.51 -6.08 -0.31 3.26e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs9790314 1.000 rs336569 chr3:161072346 T/G cg03342759 chr3:160939853 NMD3 -0.67 -8.01 -0.4 1.79e-14 Morning vs. evening chronotype; LIHC cis rs1475911 0.744 rs12481958 chr21:43517269 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 0.67 9.77 0.47 4.76e-20 IgG glycosylation; LIHC trans rs6598955 0.671 rs6658935 chr1:26568912 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.81 -9.1 -0.44 7.57e-18 Obesity-related traits; LIHC cis rs6582630 0.555 rs7301250 chr12:38596244 G/T cg13010199 chr12:38710504 ALG10B 0.53 6.31 0.32 8.67e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs9916302 0.706 rs8069074 chr17:37685401 C/T cg07936489 chr17:37558343 FBXL20 0.84 11.81 0.54 3.05e-27 Glomerular filtration rate (creatinine); LIHC cis rs801193 1.000 rs2659912 chr7:66157999 G/C cg11764359 chr7:65958608 NA 0.71 10.56 0.5 9.29e-23 Aortic root size; LIHC cis rs7909074 1.000 rs4948925 chr10:45392455 C/T cg05187965 chr10:45406764 TMEM72 -0.28 -6.9 -0.35 2.48e-11 Mean corpuscular volume; LIHC trans rs1005277 0.579 rs1548255 chr10:38417193 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.25 0.32 1.24e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12479064 0.604 rs11893359 chr2:99954608 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.68 -8.47 -0.42 7.57e-16 Chronic sinus infection; LIHC cis rs10504229 0.834 rs7015674 chr8:58153166 C/T cg21724239 chr8:58056113 NA 0.43 5.85 0.3 1.18e-8 Developmental language disorder (linguistic errors); LIHC cis rs3790645 1.000 rs369385 chr1:26893229 C/T cg17456097 chr1:26900765 RPS6KA1 0.4 5.82 0.3 1.33e-8 Glucose homeostasis traits; LIHC cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.89 -12.95 -0.57 1.71e-31 Alzheimer's disease; LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs992157 0.798 rs2382818 chr2:219155907 A/T cg20019365 chr2:219134978 PNKD;AAMP -0.77 -11.96 -0.54 8.84e-28 Colorectal cancer; LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.6 9.26 0.45 2.38e-18 Height; LIHC cis rs2838344 0.776 rs2298561 chr21:45085234 A/G cg01579765 chr21:45077557 HSF2BP -0.34 -6.27 -0.32 1.1e-9 Coronary artery disease; LIHC cis rs936229 0.784 rs12906946 chr15:75153140 A/G cg10253484 chr15:75165896 SCAMP2 -0.57 -6.44 -0.33 4.08e-10 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs74181299 0.520 rs11684110 chr2:65368290 A/G cg05010058 chr2:65284262 CEP68 -0.35 -5.81 -0.3 1.45e-8 Pulse pressure; LIHC cis rs6424115 1.000 rs35385477 chr1:24155924 G/A cg15997130 chr1:24165203 NA 0.47 9.75 0.47 5.69e-20 Immature fraction of reticulocytes; LIHC cis rs769267 0.929 rs2965180 chr19:19491973 T/C cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.01 -0.31 4.78e-9 Tonsillectomy; LIHC cis rs9359856 0.564 rs72915904 chr6:90421412 C/A cg13799429 chr6:90582589 CASP8AP2 -0.69 -6.36 -0.33 6.49e-10 Bipolar disorder; LIHC cis rs1790761 0.658 rs684928 chr11:67329742 G/A cg01069141 chr11:67398826 TBX10;NUDT8 0.37 6.51 0.33 2.68e-10 Mean corpuscular volume; LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg07157834 chr1:205819609 PM20D1 0.67 10.1 0.48 3.76e-21 Menarche (age at onset); LIHC cis rs9640161 0.789 rs6964110 chr7:150041836 A/C cg27494647 chr7:150038898 RARRES2 0.31 6.04 0.31 3.99e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs2549003 1.000 rs2549003 chr5:131829297 A/G cg02551604 chr5:131831745 NA -0.45 -6.82 -0.35 4.08e-11 Asthma (sex interaction); LIHC cis rs950169 0.922 rs12912934 chr15:85114447 C/T cg17507749 chr15:85114479 UBE2QP1 0.77 8.87 0.43 4.26e-17 Schizophrenia; LIHC cis rs7829975 0.846 rs7005216 chr8:8547110 C/G cg06636001 chr8:8085503 FLJ10661 -0.42 -6.72 -0.34 7.41e-11 Mood instability; LIHC cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg27297192 chr10:134578999 INPP5A 0.53 7.39 0.37 1.15e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7927771 0.524 rs11039402 chr11:47826090 A/C cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC cis rs6963495 0.745 rs73192150 chr7:105211610 A/C cg19920283 chr7:105172520 RINT1 0.66 6.02 0.31 4.39e-9 Bipolar disorder (body mass index interaction); LIHC cis rs2976388 0.565 rs2572905 chr8:143797104 C/T cg13446199 chr8:143762866 PSCA -0.2 -5.76 -0.3 1.85e-8 Urinary tract infection frequency; LIHC cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.22 -0.36 3.41e-12 Bipolar disorder; LIHC cis rs55665837 0.665 rs11023273 chr11:14630819 G/A cg19336497 chr11:14380999 RRAS2 -0.37 -6.21 -0.32 1.57e-9 Vitamin D levels; LIHC cis rs6912958 0.781 rs6940150 chr6:88287114 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC trans rs1814175 0.615 rs4545557 chr11:50027329 A/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs600806 0.778 rs518697 chr1:110014778 G/A cg23091122 chr1:110024289 SYPL2 -0.44 -6.09 -0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs1348850 0.801 rs11890163 chr2:178327134 G/A cg27490568 chr2:178487706 NA 0.81 7.56 0.38 3.8e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs7644516 0.646 rs2052761 chr3:25924669 A/G cg26542501 chr3:124449238 UMPS -0.46 -6.2 -0.32 1.61e-9 DNA methylation (variation); LIHC cis rs898097 0.841 rs4986136 chr17:80865119 A/G cg15664640 chr17:80829946 TBCD 0.72 11.73 0.54 6.15e-27 Breast cancer; LIHC cis rs7149337 0.836 rs11622116 chr14:51670744 C/T cg23942311 chr14:51606299 NA 0.34 6.69 0.34 9.17e-11 Cancer; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.58 -8.31 -0.41 2.22e-15 Lymphocyte counts; LIHC cis rs9814567 0.806 rs4245903 chr3:134317074 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.56 -9.38 -0.45 9.05e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs782590 0.774 rs782629 chr2:55900283 C/T cg18811423 chr2:55921094 PNPT1 -0.87 -13.79 -0.6 1.06e-34 Metabolic syndrome; LIHC cis rs4713118 0.911 rs9461406 chr6:27719764 C/T cg20933634 chr6:27740509 NA -0.47 -6.11 -0.31 2.67e-9 Parkinson's disease; LIHC cis rs7223966 1.000 rs8075422 chr17:61804686 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 7.11 0.36 6.76e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs8014204 0.935 rs4903267 chr14:75360419 G/T cg08847533 chr14:75593920 NEK9 -0.38 -6.46 -0.33 3.59e-10 Caffeine consumption; LIHC cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs700651 0.789 rs116165148 chr2:198888347 T/G cg00792783 chr2:198669748 PLCL1 0.41 5.93 0.31 7.58e-9 Intracranial aneurysm; LIHC cis rs7582180 0.629 rs11686799 chr2:100956055 C/G cg14675211 chr2:100938903 LONRF2 0.54 8.54 0.42 4.39e-16 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.967 rs10769973 chr11:8928615 C/G cg12365402 chr11:9010492 NRIP3 0.31 7.91 0.39 3.7e-14 Hemoglobin concentration; LIHC cis rs12368653 0.607 rs7966795 chr12:58031413 C/A cg12615879 chr12:58013172 SLC26A10 0.36 7.12 0.36 6.52e-12 Multiple sclerosis; LIHC cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg06481639 chr22:41940642 POLR3H -0.63 -6.52 -0.33 2.58e-10 Vitiligo; LIHC cis rs7097610 1 rs7097610 chr10:82304162 C/T cg01528321 chr10:82214614 TSPAN14 -0.67 -7.23 -0.36 3.27e-12 Post bronchodilator FEV1; LIHC cis rs3736485 0.903 rs11630743 chr15:51750609 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.24 -0.32 1.26e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg11764359 chr7:65958608 NA 0.58 5.9 0.3 8.51e-9 Diabetic kidney disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24634408 chr4:177250214 SPCS3 0.27 6.22 0.32 1.48e-9 Cognitive function; LIHC cis rs2153535 0.580 rs986060 chr6:8465428 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs7528419 1.000 rs7528419 chr1:109817192 A/G cg22346081 chr1:109937191 SORT1 -0.51 -6.02 -0.31 4.51e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs3780378 0.875 rs7869668 chr9:5069837 G/A cg02405213 chr9:5042618 JAK2 -0.52 -9.2 -0.45 3.68e-18 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs10751667 0.600 rs7394783 chr11:1005108 C/T ch.11.42038R chr11:967971 AP2A2 -0.57 -10.8 -0.5 1.38e-23 Alzheimer's disease (late onset); LIHC cis rs4699052 0.662 rs1996346 chr4:104250324 C/T cg16532752 chr4:104119610 CENPE -0.37 -5.75 -0.3 2e-8 Testicular germ cell tumor; LIHC cis rs986417 0.901 rs1884098 chr14:61038944 A/T cg27398547 chr14:60952738 C14orf39 0.79 9.08 0.44 8.8e-18 Gut microbiota (bacterial taxa); LIHC cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg09913183 chr17:42254507 C17orf65;ASB16 -0.63 -9.31 -0.45 1.55e-18 Total body bone mineral density; LIHC cis rs35883536 0.609 rs10783142 chr1:101043902 C/G cg14515779 chr1:101123966 NA 0.47 6.73 0.34 7.27e-11 Monocyte count; LIHC cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg06212747 chr3:49208901 KLHDC8B 0.58 7.58 0.38 3.23e-13 Parkinson's disease; LIHC cis rs1801251 1.000 rs1947105 chr2:233721455 A/G cg25237894 chr2:233734115 C2orf82 0.57 10.94 0.51 4.38e-24 Coronary artery disease; LIHC cis rs1499614 0.522 rs13247442 chr7:66188858 T/C cg12463550 chr7:65579703 CRCP 0.78 6.81 0.35 4.52e-11 Gout; LIHC trans rs17685 0.725 rs2302436 chr7:75676988 A/T cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.32 -0.7 1.01e-52 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs782590 0.967 rs58003472 chr2:55797507 T/C cg18811423 chr2:55921094 PNPT1 0.95 15.72 0.65 2.84e-42 Metabolic syndrome; LIHC cis rs11098499 0.566 rs7664440 chr4:120578540 A/G cg09307838 chr4:120376055 NA 0.64 9.32 0.45 1.51e-18 Corneal astigmatism; LIHC cis rs8180040 0.715 rs6772670 chr3:47191349 G/A cg16586182 chr3:47516702 SCAP -0.5 -8.93 -0.43 2.66e-17 Colorectal cancer; LIHC cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg11502198 chr6:26597334 ABT1 0.42 6.0 0.31 5.07e-9 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg22907277 chr7:1156413 C7orf50 0.43 6.12 0.31 2.51e-9 Longevity;Endometriosis; LIHC cis rs17102423 0.723 rs8181939 chr14:65555758 G/A cg11161011 chr14:65562177 MAX -0.53 -7.58 -0.38 3.19e-13 Obesity-related traits; LIHC cis rs10089 1.000 rs72794401 chr5:127517626 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.47 0.33 3.39e-10 Ileal carcinoids; LIHC cis rs5753618 0.509 rs1034589 chr22:31579233 C/T cg22777020 chr22:31556080 RNF185 -0.56 -6.47 -0.33 3.38e-10 Colorectal cancer; LIHC cis rs11190604 1.000 rs10883502 chr10:102238343 T/G cg07080220 chr10:102295463 HIF1AN 0.5 7.06 0.36 9.17e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg17328964 chr8:145687451 CYHR1 0.56 9.99 0.48 8.35e-21 Age at first birth; LIHC cis rs7666738 0.830 rs7664169 chr4:99037859 C/T cg05340658 chr4:99064831 C4orf37 -0.71 -13.31 -0.58 7.39e-33 Colonoscopy-negative controls vs population controls; LIHC cis rs7503807 0.905 rs62068345 chr17:78608040 C/T cg09596252 chr17:78655493 RPTOR 0.39 6.95 0.35 1.88e-11 Obesity; LIHC cis rs7408868 1.000 rs10415431 chr19:15277027 G/A cg02272795 chr19:15279244 NOTCH3 -0.32 -5.79 -0.3 1.61e-8 Pulse pressure; LIHC trans rs637571 0.546 rs11227309 chr11:65584512 A/C cg17712092 chr4:129076599 LARP1B -0.69 -10.6 -0.5 6.74e-23 Eosinophil percentage of white cells; LIHC cis rs6964587 1.000 rs12537846 chr7:91721581 C/T cg17063962 chr7:91808500 NA -1.0 -19.13 -0.72 5.67e-56 Breast cancer; LIHC cis rs6831352 0.918 rs2851248 chr4:100045974 A/G cg12011299 chr4:100065546 ADH4 0.48 8.61 0.42 2.62e-16 Alcohol dependence; LIHC cis rs2070488 1.000 rs36006749 chr3:38443312 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.84 0.65 9.2e-43 Electrocardiographic conduction measures; LIHC cis rs7395581 0.797 rs10742801 chr11:47342220 A/C cg26139080 chr11:47293733 MADD -0.5 -8.36 -0.41 1.64e-15 HDL cholesterol; LIHC cis rs317689 0.690 rs7969559 chr12:69655167 A/G cg20891283 chr12:69753455 YEATS4 0.48 7.09 0.36 7.95e-12 Response to diuretic therapy; LIHC cis rs10779751 0.734 rs2791649 chr1:11132561 A/G cg08854313 chr1:11322531 MTOR 0.66 10.07 0.48 4.8e-21 Body mass index; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23939932 chr2:242664240 ING5 -0.4 -6.08 -0.31 3.14e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7412746 0.658 rs7526489 chr1:150726238 C/T cg18016565 chr1:150552671 MCL1 0.56 10.68 0.5 3.68e-23 Melanoma; LIHC cis rs4808199 0.948 rs8108647 chr19:19427623 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.54 7.86 0.39 5.17e-14 Nonalcoholic fatty liver disease; LIHC cis rs11605275 1.000 rs76735151 chr11:20026419 G/A cg14835545 chr11:20032148 NAV2 -0.71 -6.63 -0.34 1.32e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4595586 0.505 rs11613808 chr12:39390823 T/A cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.86 -0.3 1.11e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4759375 0.598 rs11060762 chr12:123403710 C/A cg25930673 chr12:123319894 HIP1R 0.62 6.43 0.33 4.2e-10 HDL cholesterol; LIHC cis rs6061231 1.000 rs11696991 chr20:60959694 G/T cg06026331 chr20:60912101 LAMA5 0.39 5.79 0.3 1.59e-8 Colorectal cancer; LIHC cis rs1003719 0.586 rs2298685 chr21:38533390 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs611744 0.967 rs584555 chr8:109218612 C/G cg18478394 chr8:109455254 TTC35 0.42 7.18 0.36 4.37e-12 Dupuytren's disease; LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.01e-19 Renal cell carcinoma; LIHC cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg09913183 chr17:42254507 C17orf65;ASB16 -0.77 -11.73 -0.54 6.02e-27 Total body bone mineral density; LIHC trans rs60843830 1.000 rs9213 chr2:218386 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.6 8.49 0.42 6.42e-16 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs7085104 0.700 rs6163 chr10:104596924 C/A cg15744005 chr10:104629667 AS3MT -0.39 -8.91 -0.43 3.09e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs2635047 0.638 rs2571006 chr18:44718515 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.86 0.3 1.07e-8 Educational attainment; LIHC cis rs2629540 0.847 rs11245342 chr10:126414084 C/T cg08799069 chr10:126477246 METTL10 0.5 7.96 0.4 2.49e-14 Cocaine dependence; LIHC cis rs7258015 1.000 rs7257871 chr19:10449252 T/C cg13981319 chr19:10446556 ICAM3 0.46 7.21 0.36 3.68e-12 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs4908768 0.657 rs1353130 chr1:8822364 T/C cg20416874 chr1:8611966 RERE 0.46 6.59 0.34 1.64e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3760776 0.522 rs78060698 chr19:5832773 G/A cg25387410 chr19:5844109 FUT3 -0.63 -7.27 -0.37 2.43e-12 N-glycan levels;Tumor biomarkers;Vitamin B12 levels; LIHC cis rs882732 1.000 rs910342 chr14:95038047 G/T cg14866387 chr14:95027382 SERPINA4 -0.46 -6.19 -0.32 1.74e-9 Blood protein levels; LIHC cis rs8180040 0.620 rs2278963 chr3:47054869 G/T cg16586182 chr3:47516702 SCAP 0.47 8.18 0.4 5.76e-15 Colorectal cancer; LIHC cis rs780096 0.527 rs11127044 chr2:27740404 C/G cg22903471 chr2:27725779 GCKR -0.53 -9.05 -0.44 1.1e-17 Total body bone mineral density; LIHC cis rs9527 0.518 rs11191530 chr10:104800044 C/T cg15744005 chr10:104629667 AS3MT 0.46 6.37 0.33 6.22e-10 Arsenic metabolism; LIHC cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg11764359 chr7:65958608 NA -0.57 -5.92 -0.31 7.72e-9 Diabetic kidney disease; LIHC cis rs6502050 0.835 rs4789722 chr17:80151881 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.91 -0.3 8.14e-9 Life satisfaction; LIHC trans rs6598955 0.627 rs3924324 chr1:26616280 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.18 -0.4 5.47e-15 Obesity-related traits; LIHC cis rs1403694 1.000 rs1648716 chr3:186439529 C/T cg12454167 chr3:186435060 KNG1 0.29 7.17 0.36 4.62e-12 Blood protein levels; LIHC cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg08499158 chr17:42289980 UBTF -0.49 -8.09 -0.4 1.03e-14 Total body bone mineral density; LIHC trans rs1945213 0.659 rs17149979 chr11:55840862 A/G cg15704280 chr7:45808275 SEPT13 0.59 7.58 0.38 3.25e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs7927592 0.956 rs12277225 chr11:68340967 T/C cg01657329 chr11:68192670 LRP5 -0.48 -6.31 -0.32 8.41e-10 Total body bone mineral density; LIHC cis rs35762459 1 rs35762459 chr11:8844653 T/TA cg12365402 chr11:9010492 NRIP3 -0.27 -6.64 -0.34 1.27e-10 Immature fraction of reticulocytes; LIHC cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg23283495 chr1:209979779 IRF6 -0.43 -6.98 -0.35 1.5e-11 Monobrow; LIHC cis rs3857067 0.740 rs6532470 chr4:95108211 C/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.58 -0.38 3.29e-13 QT interval; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg13152130 chr6:118910203 C6orf204 -0.65 -7.47 -0.37 6.87e-13 Diastolic blood pressure; LIHC cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg26752003 chr8:145688521 CYHR1 0.41 6.1 0.31 2.84e-9 Age at first birth; LIHC cis rs7224737 0.789 rs8071235 chr17:40300126 C/A cg02450064 chr17:40260053 DHX58 -0.3 -6.07 -0.31 3.47e-9 Fibrinogen levels; LIHC cis rs370915 0.542 rs1425953 chr4:187833652 A/C cg19519643 chr4:187840862 NA -0.56 -9.8 -0.47 3.86e-20 Gout; LIHC trans rs1814175 0.586 rs10769603 chr11:49688837 T/C cg18944383 chr4:111397179 ENPEP 0.25 6.14 0.32 2.3e-9 Height; LIHC cis rs12620999 0.938 rs4575672 chr2:238070572 T/C cg23555395 chr2:238036564 NA -0.32 -5.94 -0.31 6.94e-9 Systemic lupus erythematosus; LIHC cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs876084 0.505 rs12541796 chr8:121112830 G/A cg06265175 chr8:121136014 COL14A1 0.48 7.83 0.39 6.23e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs561341 1.000 rs4795668 chr17:30244554 G/A cg12193833 chr17:30244370 NA -0.57 -6.01 -0.31 4.63e-9 Hip circumference adjusted for BMI; LIHC cis rs7619427 1.000 rs6788179 chr3:44062007 G/A cg24966902 chr3:44043705 NA 0.53 7.37 0.37 1.31e-12 Schizophrenia; LIHC cis rs17253792 0.545 rs12883972 chr14:56018020 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.37 -0.33 6.18e-10 Putamen volume; LIHC cis rs10504073 0.584 rs7818507 chr8:49918423 G/T cg00325661 chr8:49890786 NA 0.39 9.57 0.46 2.29e-19 Blood metabolite ratios; LIHC cis rs2439831 1.000 rs2264239 chr15:43765533 C/G cg15269541 chr15:43626905 ADAL -0.3 -5.88 -0.3 9.9e-9 Lung cancer in ever smokers; LIHC cis rs4631830 0.720 rs12412140 chr10:51503977 T/C cg20129853 chr10:51489980 NA 0.4 8.66 0.42 1.88e-16 Prostate-specific antigen levels; LIHC cis rs28830936 1.000 rs2412622 chr15:41960311 A/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -5.88 -0.3 9.69e-9 Diastolic blood pressure; LIHC cis rs2625529 0.824 rs12595464 chr15:72294398 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.81 -0.3 1.47e-8 Red blood cell count; LIHC cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg18357526 chr6:26021779 HIST1H4A 0.54 7.21 0.36 3.61e-12 Blood metabolite levels; LIHC cis rs921968 0.643 rs832801 chr2:219488698 G/A cg18887096 chr2:219472410 PLCD4 0.35 6.06 0.31 3.63e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7116495 1.000 rs73539529 chr11:71815596 T/C cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs7911264 1.000 rs10786052 chr10:94446635 T/C cg25506282 chr10:94462361 NA 0.43 7.46 0.37 7.3e-13 Inflammatory bowel disease; LIHC cis rs7085104 0.632 rs3781287 chr10:104595420 A/C cg15744005 chr10:104629667 AS3MT -0.41 -9.73 -0.47 6.34e-20 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs7903847 0.619 rs10882912 chr10:99138077 C/T cg08345082 chr10:99160200 RRP12 -0.38 -6.25 -0.32 1.23e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs589448 0.902 rs2603090 chr12:69777188 G/A cg20891283 chr12:69753455 YEATS4 0.94 22.36 0.77 6.84e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs6860806 0.507 rs274570 chr5:131713226 C/T cg24060327 chr5:131705240 SLC22A5 0.79 12.1 0.55 2.79e-28 Breast cancer; LIHC cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9902453 0.740 rs2617867 chr17:28049399 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -13.59 -0.59 6.14e-34 Coffee consumption (cups per day); LIHC cis rs59698941 0.943 rs12517073 chr5:132240151 T/C cg02081065 chr5:132209139 LEAP2 0.26 5.73 0.3 2.23e-8 Apolipoprotein A-IV levels; LIHC cis rs965469 1.000 rs6051806 chr20:3350319 C/T cg25506879 chr20:3388711 C20orf194 -0.57 -6.43 -0.33 4.33e-10 IFN-related cytopenia; LIHC cis rs7666738 0.830 rs6532701 chr4:98745134 C/T cg05340658 chr4:99064831 C4orf37 0.64 11.35 0.52 1.45e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs4824093 0.610 rs73441745 chr22:50237606 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.76 -6.03 -0.31 4.16e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs936229 0.690 rs2445618 chr15:75035256 T/C cg14664628 chr15:75095509 CSK -0.83 -13.78 -0.6 1.2e-34 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs72627123 0.749 rs58199545 chr14:74452495 G/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.46 0.42 8.11e-16 Morning vs. evening chronotype; LIHC cis rs5769765 0.773 rs7410304 chr22:50316835 T/C cg02269571 chr22:50332266 NA -0.63 -8.59 -0.42 3.16e-16 Schizophrenia; LIHC trans rs1728785 1.000 rs1645927 chr16:68589300 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.41 0.33 4.71e-10 Ulcerative colitis; LIHC cis rs7945705 0.818 rs2742537 chr11:8908389 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -9.33 -0.45 1.33e-18 Hemoglobin concentration; LIHC cis rs12497850 1.000 rs10865952 chr3:48744484 A/G cg06212747 chr3:49208901 KLHDC8B 0.49 6.39 0.33 5.34e-10 Parkinson's disease; LIHC cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg13047869 chr3:10149882 C3orf24 0.5 6.16 0.32 2.08e-9 Alzheimer's disease; LIHC trans rs11098499 0.697 rs11941899 chr4:120382758 C/A cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs929354 0.772 rs6459739 chr7:156998863 A/T cg17757837 chr7:157058334 UBE3C 0.74 12.06 0.55 3.84e-28 Body mass index; LIHC trans rs1459104 0.571 rs10459012 chr11:55091574 C/A cg15704280 chr7:45808275 SEPT13 0.59 8.72 0.43 1.27e-16 Body mass index; LIHC trans rs11098499 0.754 rs1546503 chr4:120241167 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.58 0.42 3.36e-16 Corneal astigmatism; LIHC cis rs10861342 1.000 rs11112390 chr12:105542200 A/C cg23923672 chr12:105501055 KIAA1033 0.68 8.46 0.42 7.85e-16 IgG glycosylation; LIHC cis rs11758351 0.929 rs6906367 chr6:26187125 C/T cg06951627 chr6:26196580 NA 0.46 5.8 0.3 1.5e-8 Gout;Renal underexcretion gout; LIHC cis rs35146811 0.961 rs1880949 chr7:99722266 A/C cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 -0.42 -6.08 -0.31 3.22e-9 Coronary artery disease; LIHC cis rs2153535 0.580 rs1414346 chr6:8471574 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs12216125 0.554 rs6942196 chr6:26072804 A/G cg18357526 chr6:26021779 HIST1H4A 0.45 6.6 0.34 1.54e-10 Iron status biomarkers; LIHC cis rs7100689 0.646 rs4468295 chr10:82119276 C/G cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs9733 0.715 rs12402006 chr1:150869829 G/A cg17724175 chr1:150552817 MCL1 -0.33 -6.31 -0.32 8.86e-10 Tonsillectomy; LIHC cis rs722599 0.748 rs20578 chr14:75367807 C/T cg08847533 chr14:75593920 NEK9 -0.54 -8.77 -0.43 8.3e-17 IgG glycosylation; LIHC cis rs4243830 1.000 rs12046884 chr1:6594561 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 0.88 9.43 0.45 6.32e-19 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13921570 chr2:74730534 LOC151534;LBX2 0.39 6.23 0.32 1.38e-9 Cognitive function; LIHC cis rs9486715 0.830 rs2255552 chr6:96999643 A/G cg06623918 chr6:96969491 KIAA0776 -0.87 -15.38 -0.64 6.28e-41 Headache; LIHC cis rs76533333 0.564 rs114940891 chr13:113419784 A/T cg08557188 chr13:113420371 ATP11A -0.8 -6.03 -0.31 4.29e-9 Red cell distribution width; LIHC cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg14983838 chr19:29218262 NA 0.49 7.55 0.38 3.94e-13 Methadone dose in opioid dependence; LIHC cis rs7937682 0.889 rs1940529 chr11:111498523 G/C cg09085632 chr11:111637200 PPP2R1B -1.01 -11.89 -0.54 1.6e-27 Primary sclerosing cholangitis; LIHC cis rs35110281 0.627 rs56369437 chr21:44970275 A/G cg21573476 chr21:45109991 RRP1B -0.5 -9.31 -0.45 1.56e-18 Mean corpuscular volume; LIHC trans rs7674212 0.541 rs2615539 chr4:104081106 C/G cg16471864 chr4:38666270 KLF3;FLJ13197 -0.45 -6.44 -0.33 4.11e-10 Type 2 diabetes; LIHC cis rs11098499 0.775 rs10021601 chr4:120282563 G/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC trans rs6512645 1.000 rs6512645 chr20:49087012 A/G cg12401738 chr4:39460100 LIAS;RPL9 0.42 6.13 0.31 2.46e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -11.15 -0.52 7.67e-25 Platelet count; LIHC cis rs7959452 0.535 rs2305641 chr12:69646914 C/T cg20891283 chr12:69753455 YEATS4 0.74 13.71 0.6 2.19e-34 Blood protein levels; LIHC cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg06466757 chr4:1255808 NA 0.35 5.93 0.31 7.24e-9 Obesity-related traits; LIHC cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg16405210 chr4:1374714 KIAA1530 -0.51 -7.41 -0.37 1.02e-12 Longevity; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.74 -0.34 6.85e-11 Total body bone mineral density; LIHC trans rs10761482 0.532 rs1938533 chr10:62234109 G/C cg17314160 chr12:110399253 GIT2 -0.41 -6.11 -0.31 2.73e-9 Schizophrenia; LIHC cis rs3820068 0.705 rs2145396 chr1:15875184 A/G cg17385448 chr1:15911702 AGMAT 0.4 6.73 0.34 7.25e-11 Systolic blood pressure; LIHC trans rs11098499 0.739 rs9884728 chr4:120127079 C/T cg25214090 chr10:38739885 LOC399744 -0.38 -6.26 -0.32 1.12e-9 Corneal astigmatism; LIHC cis rs11758351 0.789 rs4496782 chr6:26184617 T/C cg16070018 chr6:26224392 HIST1H3E 0.44 6.16 0.32 2.09e-9 Gout;Renal underexcretion gout; LIHC trans rs1005277 0.589 rs2749624 chr10:38529865 A/G cg17830980 chr10:43048298 ZNF37B -0.5 -9.5 -0.46 3.77e-19 Extrinsic epigenetic age acceleration; LIHC cis rs12220238 0.915 rs10824164 chr10:76137032 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2257205 0.667 rs8075108 chr17:56657248 G/A cg05425664 chr17:57184151 TRIM37 -0.61 -6.69 -0.34 8.94e-11 Pancreatic cancer; LIHC cis rs12908161 1.000 rs35808647 chr15:85377441 G/A cg12863693 chr15:85201151 NMB 0.44 6.06 0.31 3.66e-9 Schizophrenia; LIHC cis rs6089584 0.586 rs1079755 chr20:60615262 G/A cg06108461 chr20:60628389 TAF4 -0.62 -8.47 -0.42 7.53e-16 Body mass index; LIHC cis rs400736 0.550 rs426561 chr1:8057254 T/C cg25007680 chr1:8021821 PARK7 0.53 7.16 0.36 5.06e-12 Response to antidepressants and depression; LIHC cis rs7772486 0.686 rs9485019 chr6:146046381 C/G cg23711669 chr6:146136114 FBXO30 -0.64 -11.81 -0.54 3.25e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs2997447 0.761 rs56299762 chr1:26441638 G/A cg19633962 chr1:26362018 EXTL1 -0.65 -5.98 -0.31 5.59e-9 QRS complex (12-leadsum); LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg14651457 chr8:12611650 LONRF1 -0.54 -6.78 -0.34 5.37e-11 Monocyte count; LIHC cis rs9473924 0.505 rs7768747 chr6:50931762 G/A cg14470998 chr6:50812995 TFAP2B 0.86 7.83 0.39 6.39e-14 Body mass index; LIHC cis rs8062405 1.000 rs72793811 chr16:28839392 G/A cg16576597 chr16:28551801 NUPR1 0.37 5.85 0.3 1.13e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1865760 0.516 rs9295684 chr6:26069669 T/C cg17691542 chr6:26056736 HIST1H1C 0.45 6.37 0.33 6.04e-10 Height; LIHC cis rs2522056 1.000 rs62385693 chr5:131773674 T/C cg24060327 chr5:131705240 SLC22A5 0.59 8.04 0.4 1.49e-14 Lymphocyte counts;Fibrinogen; LIHC cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg05564831 chr3:52568323 NT5DC2 0.34 5.89 0.3 9.43e-9 Electroencephalogram traits; LIHC cis rs9457247 0.967 rs425039 chr6:167410527 C/T cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC cis rs4950322 0.512 rs12409455 chr1:146850284 A/G cg25205988 chr1:146714368 CHD1L -0.41 -5.95 -0.31 6.75e-9 Protein quantitative trait loci; LIHC cis rs7106204 0.609 rs11824883 chr11:24284952 G/A ch.11.24196551F chr11:24239977 NA 0.69 6.41 0.33 4.84e-10 Response to Homoharringtonine (cytotoxicity); LIHC trans rs2363709 1.000 rs2363709 chr3:67417105 G/A cg22969669 chr19:19613165 GATAD2A 0.66 6.13 0.31 2.48e-9 IgE levels; LIHC cis rs240764 0.658 rs35967345 chr6:101187858 T/G cg09795085 chr6:101329169 ASCC3 -0.46 -6.69 -0.34 9.07e-11 Neuroticism; LIHC cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.64e-30 Menopause (age at onset); LIHC trans rs12960119 0.536 rs12957996 chr18:23723250 C/T cg05333146 chr16:67183725 B3GNT9 0.64 6.06 0.31 3.57e-9 Rhegmatogenous retinal detachment; LIHC cis rs8017423 0.967 rs2401875 chr14:90688451 A/G cg14092571 chr14:90743983 NA -0.37 -5.92 -0.3 7.73e-9 Mortality in heart failure; LIHC trans rs728616 0.681 rs12769764 chr10:81917113 C/G cg16781439 chr22:29469035 KREMEN1 0.4 6.14 0.32 2.28e-9 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs739401 0.566 rs7931504 chr11:3026712 C/T cg08508325 chr11:3079039 CARS -0.32 -6.72 -0.34 7.69e-11 Longevity; LIHC cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg04025307 chr7:1156635 C7orf50 0.65 11.43 0.53 7.39e-26 Longevity;Endometriosis; LIHC cis rs4742903 0.935 rs9942894 chr9:106914905 A/G cg14250997 chr9:106856677 SMC2 0.37 6.35 0.32 6.73e-10 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.8e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6748734 1.000 rs4311055 chr2:241821017 T/C cg09990169 chr2:241835740 C2orf54 -0.66 -9.26 -0.45 2.24e-18 Urinary metabolites; LIHC cis rs7613875 0.600 rs2247510 chr3:50126215 A/C cg05623727 chr3:50126028 RBM5 0.35 6.07 0.31 3.34e-9 Body mass index; LIHC cis rs921968 0.510 rs591573 chr2:219478193 C/T cg02985541 chr2:219472218 PLCD4 0.42 6.89 0.35 2.72e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.99 20.66 0.75 4e-62 Height; LIHC cis rs2645694 0.626 rs2703143 chr4:77830441 A/G cg03477792 chr4:77819574 ANKRD56 0.55 7.29 0.37 2.14e-12 Emphysema distribution in smoking; LIHC cis rs12824058 0.831 rs4759655 chr12:130815740 A/G cg24838063 chr12:130822603 PIWIL1 -0.67 -9.93 -0.47 1.42e-20 Menopause (age at onset); LIHC cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg23758822 chr17:41437982 NA 0.94 17.61 0.69 7.29e-50 Menopause (age at onset); LIHC cis rs1552244 0.608 rs6764807 chr3:9998803 T/C cg21531657 chr3:10005747 TMEM111 0.39 5.83 0.3 1.28e-8 Alzheimer's disease; LIHC cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg14983838 chr19:29218262 NA 0.49 7.55 0.38 3.94e-13 Methadone dose in opioid dependence; LIHC cis rs1046896 0.628 rs12452314 chr17:80723362 A/G cg00809820 chr17:80708513 TBCD;FN3K 0.35 6.0 0.31 5.03e-9 Glycated hemoglobin levels; LIHC cis rs9733 0.818 rs10888388 chr1:150687296 C/T cg13175981 chr1:150552382 MCL1 0.52 8.07 0.4 1.17e-14 Tonsillectomy; LIHC cis rs11583043 0.957 rs6577223 chr1:101499750 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 7.97 0.4 2.34e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs1005277 0.522 rs1208684 chr10:38093936 G/A cg23533926 chr12:111358616 MYL2 -0.31 -6.18 -0.32 1.85e-9 Extrinsic epigenetic age acceleration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25216613 chr1:3541447 TPRG1L -0.6 -6.98 -0.35 1.58e-11 Systolic blood pressure; LIHC cis rs9902453 0.933 rs7225462 chr17:28321226 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.96 0.6 2.31e-35 Coffee consumption (cups per day); LIHC cis rs6912958 0.781 rs9450752 chr6:88300013 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC cis rs12701220 0.857 rs1057558 chr7:1062366 A/G cg16145915 chr7:1198662 ZFAND2A -0.31 -5.96 -0.31 6.11e-9 Bronchopulmonary dysplasia; LIHC cis rs9902453 0.808 rs56088359 chr17:28173659 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.97 0.54 8.37e-28 Coffee consumption (cups per day); LIHC trans rs561341 0.882 rs563539 chr17:30307958 A/G cg20587970 chr11:113659929 NA -1.23 -10.59 -0.5 7.19e-23 Hip circumference adjusted for BMI; LIHC cis rs10878977 0.586 rs2006838 chr12:69816232 A/C cg17330252 chr12:69809627 NA 0.37 5.88 0.3 9.79e-9 Colorectal cancer; LIHC cis rs36051895 0.659 rs62541539 chr9:5038180 C/T cg02405213 chr9:5042618 JAK2 -0.71 -12.43 -0.56 1.57e-29 Pediatric autoimmune diseases; LIHC cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg12042659 chr19:58951599 ZNF132 0.38 6.38 0.33 5.89e-10 Uric acid clearance; LIHC trans rs4824093 0.610 rs73443906 chr22:50274293 A/G cg09872104 chr7:134855509 C7orf49 -0.76 -6.09 -0.31 2.99e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs9948 0.655 rs62156228 chr2:97420335 A/G cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7264396 0.563 rs59064961 chr20:34307950 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.76 -0.43 9.08e-17 Total cholesterol levels; LIHC cis rs7106204 0.513 rs7131112 chr11:24249402 A/G ch.11.24196551F chr11:24239977 NA 0.79 10.77 0.5 1.71e-23 Response to Homoharringtonine (cytotoxicity); LIHC cis rs9905704 0.647 rs9898048 chr17:57108543 C/T cg05425664 chr17:57184151 TRIM37 -0.41 -5.87 -0.3 1e-8 Testicular germ cell tumor; LIHC cis rs611744 0.935 rs679077 chr8:109244742 G/T cg18478394 chr8:109455254 TTC35 0.38 6.55 0.33 2.09e-10 Dupuytren's disease; LIHC cis rs763014 1.000 rs2269558 chr16:682250 C/T cg00908189 chr16:619842 PIGQ 0.81 12.74 0.57 1.12e-30 Height; LIHC cis rs8017423 0.967 rs59980414 chr14:90687738 G/C cg04374321 chr14:90722782 PSMC1 0.71 13.42 0.59 2.79e-33 Mortality in heart failure; LIHC cis rs7618501 1.000 rs7648987 chr3:49868455 A/G cg21467203 chr3:49911342 NA -0.41 -7.17 -0.36 4.75e-12 Intelligence (multi-trait analysis); LIHC cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 9.59 0.46 1.93e-19 Mean platelet volume; LIHC cis rs11608355 0.545 rs12819142 chr12:109896316 G/T cg05360138 chr12:110035743 NA 0.97 10.75 0.5 2.07e-23 Neuroticism; LIHC cis rs6840360 0.638 rs6816002 chr4:152589439 C/T cg22705602 chr4:152727874 NA -0.31 -6.44 -0.33 3.95e-10 Intelligence (multi-trait analysis); LIHC cis rs55665837 0.701 rs11023278 chr11:14641184 G/T cg16394018 chr11:14927549 NA 0.41 5.71 0.3 2.45e-8 Vitamin D levels; LIHC cis rs10792665 1.000 rs10792665 chr11:82649768 G/T cg24227371 chr11:82718527 RAB30 -0.29 -6.56 -0.33 1.99e-10 Obesity-related traits; LIHC cis rs924607 0.583 rs12516251 chr5:608939 C/T cg07001201 chr5:642380 CEP72 0.42 7.5 0.38 5.37e-13 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs2262909 0.962 rs73019889 chr19:22277826 C/G cg17074339 chr11:11642133 GALNTL4 0.45 7.11 0.36 6.86e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2033711 0.870 rs1051500 chr19:58944402 A/G cg26874164 chr19:58962979 ZNF324B 0.43 6.01 0.31 4.72e-9 Uric acid clearance; LIHC cis rs2197308 0.692 rs1904964 chr12:37933241 T/A cg13010199 chr12:38710504 ALG10B 0.49 5.77 0.3 1.79e-8 Morning vs. evening chronotype; LIHC cis rs597539 0.617 rs598353 chr11:68635770 C/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.02e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs4862750 0.914 rs11945845 chr4:187874136 T/C cg03452623 chr4:187889614 NA -0.33 -8.4 -0.41 1.24e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs12620999 1.000 rs28727919 chr2:238003313 C/T cg15676719 chr1:167598521 RCSD1 0.38 6.64 0.34 1.2e-10 Systemic lupus erythematosus; LIHC cis rs25645 0.502 rs1007654 chr17:38111354 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.49 -7.29 -0.37 2.19e-12 Myeloid white cell count; LIHC cis rs9649213 0.614 rs59120980 chr7:98017730 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.56 -9.8 -0.47 3.81e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs7568458 0.660 rs55692129 chr2:85792404 A/T cg02493740 chr2:85810744 VAMP5 -0.52 -8.5 -0.42 5.84e-16 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7523273 0.627 rs2724389 chr1:207933648 T/C cg22525895 chr1:207977042 MIR29B2 0.64 10.3 0.49 7.46e-22 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24835014 chr4:76911891 SDAD1 -0.45 -6.19 -0.32 1.7e-9 Pancreatic cancer; LIHC cis rs7131987 0.650 rs7954871 chr12:29459732 G/A cg14222432 chr12:29376421 FAR2 0.35 6.68 0.34 9.96e-11 QT interval; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22352273 chr2:238969464 SCLY 0.57 7.42 0.37 9.08e-13 Lung function (FEV1/FVC); LIHC trans rs8073060 0.586 rs225256 chr17:33955756 C/T cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs10876993 0.890 rs2619441 chr12:58083015 C/A cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.13 -0.31 2.35e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs2795502 1.000 rs1581702 chr10:43344246 G/A cg20628663 chr10:43360327 NA 0.46 7.2 0.36 3.87e-12 Blood protein levels; LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg12379764 chr21:47803548 PCNT -0.55 -8.15 -0.4 6.76e-15 Testicular germ cell tumor; LIHC cis rs7772486 0.790 rs2254257 chr6:146203724 C/T cg23711669 chr6:146136114 FBXO30 0.71 12.45 0.56 1.28e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs7843479 0.601 rs4872209 chr8:21848832 A/T cg17168535 chr8:21777572 XPO7 0.55 9.91 0.47 1.65e-20 Mean corpuscular volume; LIHC cis rs9649465 0.902 rs10253850 chr7:123273095 T/C cg03229431 chr7:123269106 ASB15 -0.42 -9.27 -0.45 2.12e-18 Migraine; LIHC cis rs17152411 0.600 rs10901841 chr10:126632386 C/A cg07906193 chr10:126599966 NA -0.29 -5.72 -0.3 2.35e-8 Height; LIHC trans rs7819412 0.502 rs11777918 chr8:11036919 A/G cg09357268 chr20:43379437 KCNK15 -0.29 -6.07 -0.31 3.31e-9 Triglycerides; LIHC cis rs12478296 1.000 rs12474070 chr2:243039738 C/T cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.1e-27 Obesity-related traits; LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg02782426 chr3:40428986 ENTPD3 0.34 6.2 0.32 1.62e-9 Renal cell carcinoma; LIHC cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 9.57 0.46 2.2e-19 Attention deficit hyperactivity disorder; LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg10755058 chr3:40428713 ENTPD3 0.4 6.95 0.35 1.89e-11 Renal cell carcinoma; LIHC cis rs8180040 1.000 rs295449 chr3:47375955 G/A cg16586182 chr3:47516702 SCAP -0.54 -9.83 -0.47 2.93e-20 Colorectal cancer; LIHC cis rs1395 1.000 rs1275538 chr2:27441397 C/T cg23587288 chr2:27483067 SLC30A3 -0.31 -5.91 -0.3 8.1e-9 Blood metabolite levels; LIHC cis rs7927592 0.956 rs7124078 chr11:68298633 G/T cg01657329 chr11:68192670 LRP5 -0.47 -6.2 -0.32 1.65e-9 Total body bone mineral density; LIHC cis rs34375054 0.526 rs4412800 chr12:125674742 C/T cg25124228 chr12:125621409 AACS 0.45 7.97 0.4 2.42e-14 Post bronchodilator FEV1/FVC ratio; LIHC cis rs17776563 0.959 rs1348003 chr15:89113441 G/C cg05013243 chr15:89149849 MIR1179 0.45 7.51 0.38 5.07e-13 Thyroid hormone levels; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.04 0.55 4.65e-28 Prudent dietary pattern; LIHC cis rs7927771 0.832 rs10838699 chr11:47386073 T/C cg20135002 chr11:47629003 NA 0.51 8.67 0.42 1.77e-16 Subjective well-being; LIHC cis rs477692 1.000 rs473073 chr10:131429646 G/T cg19680672 chr10:131412579 MGMT -0.46 -7.03 -0.36 1.16e-11 Response to temozolomide; LIHC cis rs11792861 0.781 rs72607159 chr9:111764270 C/T cg05043794 chr9:111880884 C9orf5 -0.3 -7.03 -0.36 1.15e-11 Menarche (age at onset); LIHC cis rs1401999 1.000 rs6443924 chr3:183679532 A/G cg01324343 chr3:183735012 ABCC5 0.78 12.89 0.57 2.83e-31 Anterior chamber depth; LIHC cis rs2286885 0.896 rs62578061 chr9:129248219 C/T cg15282417 chr9:129245246 FAM125B 0.41 6.58 0.34 1.75e-10 Intraocular pressure; LIHC cis rs2576037 0.526 rs4258717 chr18:44456954 T/C cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.99e-10 Personality dimensions; LIHC cis rs2976388 0.967 rs2585183 chr8:143766059 C/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.85 -0.3 1.14e-8 Urinary tract infection frequency; LIHC cis rs7296418 0.961 rs4148862 chr12:123568619 A/C cg05973401 chr12:123451056 ABCB9 0.49 7.76 0.39 1.02e-13 Platelet count; LIHC cis rs34779708 0.966 rs2126984 chr10:35410291 A/G cg03585969 chr10:35415529 CREM 0.79 11.74 0.54 5.69e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7715806 0.500 rs72633983 chr5:75002845 C/T cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7772486 0.764 rs7745696 chr6:146162829 T/C cg13319975 chr6:146136371 FBXO30 -0.34 -5.73 -0.3 2.21e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs507080 0.733 rs4393358 chr11:118569097 C/T cg04173919 chr11:118528438 PHLDB1 0.33 6.09 0.31 3.01e-9 Serum metabolite levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg27402845 chr11:1000533 AP2A2 0.44 6.52 0.33 2.57e-10 Bilirubin levels; LIHC cis rs7249142 0.549 rs7260127 chr19:19280499 C/T cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B 0.37 6.28 0.32 1.02e-9 IgG glycosylation; LIHC cis rs4423214 0.840 rs1123007 chr11:71185357 G/A cg05163923 chr11:71159392 DHCR7 -0.6 -7.9 -0.39 3.79e-14 Vitamin D levels; LIHC cis rs9902453 0.967 rs12602065 chr17:28482488 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.32 0.45 1.51e-18 Coffee consumption (cups per day); LIHC cis rs3741404 0.931 rs594942 chr11:64006292 T/C cg18225595 chr11:63971243 STIP1 -0.64 -9.72 -0.47 7.28e-20 Platelet count; LIHC cis rs4631830 0.863 rs2843549 chr10:51521247 C/A cg20129853 chr10:51489980 NA -0.43 -9.44 -0.45 6.14e-19 Prostate-specific antigen levels; LIHC cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg15691649 chr6:25882328 NA -0.61 -8.21 -0.41 4.46e-15 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.774 rs7959048 chr12:37948276 T/A cg13010199 chr12:38710504 ALG10B 0.48 5.71 0.3 2.42e-8 Bladder cancer; LIHC cis rs8078723 0.866 rs11078934 chr17:38189793 C/T cg17467752 chr17:38218738 THRA 0.77 14.88 0.63 5.65e-39 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs1801251 1.000 rs283475 chr2:233654381 A/C cg08000102 chr2:233561755 GIGYF2 -0.75 -11.23 -0.52 3.98e-25 Coronary artery disease; LIHC cis rs5769765 1.000 rs4824106 chr22:50267822 T/C cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs263063 0.764 rs2291149 chr19:5077336 G/A cg18473234 chr19:5097819 KDM4B 0.56 6.99 0.35 1.47e-11 Periodontitis (CDC/AAP); LIHC cis rs2180341 0.782 rs6912196 chr6:127722732 C/G cg27446573 chr6:127587934 RNF146 0.81 13.22 0.58 1.59e-32 Breast cancer; LIHC cis rs7208859 0.673 rs11652409 chr17:29182707 T/A cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9733 0.526 rs11204698 chr1:150659545 G/A cg15448220 chr1:150897856 SETDB1 0.43 6.74 0.34 6.71e-11 Tonsillectomy; LIHC cis rs9611565 0.694 rs11090056 chr22:42095904 A/C cg06634786 chr22:41940651 POLR3H 0.56 6.16 0.32 2e-9 Vitiligo; LIHC cis rs7666738 0.830 rs10440379 chr4:98902822 G/T cg05340658 chr4:99064831 C4orf37 0.66 11.83 0.54 2.58e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs61550741 1.000 rs2833286 chr21:32499577 A/G cg23515853 chr17:79372528 BAHCC1 -0.66 -6.21 -0.32 1.55e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg17971929 chr21:40555470 PSMG1 -0.5 -7.67 -0.38 1.86e-13 Cognitive function; LIHC trans rs35668226 1.000 rs36040970 chr10:122848990 G/C cg08474467 chr16:593365 SOLH 0.41 6.04 0.31 4e-9 Type 2 diabetes; LIHC cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.58 -5.9 -0.3 8.72e-9 Diastolic blood pressure; LIHC cis rs6089584 0.893 rs6089305 chr20:60571817 T/C cg06108461 chr20:60628389 TAF4 -0.88 -13.66 -0.59 3.36e-34 Body mass index; LIHC cis rs5769765 0.624 rs138843 chr22:50183162 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.53 -6.34 -0.32 7.11e-10 Schizophrenia; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs4980532 1 rs4980532 chr11:63680719 C/T cg04362095 chr11:63592001 C11orf84 -0.46 -6.92 -0.35 2.18e-11 Pulse pressure; LIHC cis rs6504622 0.537 rs197919 chr17:45003675 C/T cg16759221 chr17:45003025 GOSR2 -0.33 -5.82 -0.3 1.38e-8 Orofacial clefts; LIHC cis rs10463316 0.817 rs6877498 chr5:150802876 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -6.2 -0.32 1.6e-9 Metabolite levels (Pyroglutamine); LIHC cis rs1865760 0.786 rs1436308 chr6:25939567 T/G cg03517284 chr6:25882590 NA -0.44 -6.65 -0.34 1.17e-10 Height; LIHC cis rs7772486 0.902 rs1125462 chr6:146417832 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.93 0.31 7.46e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12200782 0.505 rs9295696 chr6:26550288 C/T cg09904177 chr6:26538194 HMGN4 0.44 6.32 0.32 8.32e-10 Small cell lung carcinoma; LIHC cis rs911119 0.954 rs116786204 chr20:23599918 T/G cg16589663 chr20:23618590 CST3 0.72 7.6 0.38 2.88e-13 Chronic kidney disease; LIHC cis rs12586317 0.620 rs8021414 chr14:35581480 T/A cg05294307 chr14:35346193 BAZ1A -0.46 -6.81 -0.35 4.41e-11 Psoriasis; LIHC cis rs903552 0.935 rs4965387 chr15:102003209 G/A cg19295451 chr15:102010161 PCSK6 -0.45 -6.36 -0.32 6.65e-10 Diabetic kidney disease; LIHC cis rs2153535 0.580 rs9393025 chr6:8490618 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs17401966 0.800 rs12725210 chr1:10416993 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.89 -0.35 2.63e-11 Hepatocellular carcinoma; LIHC cis rs12995491 0.933 rs34366691 chr2:88537451 G/A cg24977027 chr2:88469347 THNSL2 -0.34 -5.96 -0.31 6.14e-9 Response to metformin (IC50); LIHC cis rs1059312 0.545 rs7312683 chr12:129280105 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.5 -7.69 -0.38 1.59e-13 Systemic lupus erythematosus; LIHC cis rs7238033 0.624 rs8096571 chr18:43314473 T/A cg20610511 chr18:43302872 SLC14A1 0.37 6.24 0.32 1.31e-9 Bladder cancer; LIHC cis rs7131987 0.650 rs12366527 chr12:29474256 C/G cg00204748 chr12:29376779 FAR2 0.4 7.49 0.38 5.92e-13 QT interval; LIHC trans rs1814175 0.646 rs10839335 chr11:49715265 G/T cg03929089 chr4:120376271 NA -0.86 -16.65 -0.67 5.35e-46 Height; LIHC cis rs17685 0.753 rs2108274 chr7:75781636 C/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg07636037 chr3:49044803 WDR6 0.76 12.7 0.57 1.59e-30 Menarche (age at onset); LIHC cis rs2033711 0.840 rs3764533 chr19:58929194 A/G cg00825309 chr19:58991885 ZNF446 -0.6 -9.2 -0.45 3.53e-18 Uric acid clearance; LIHC cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg18404041 chr3:52824283 ITIH1 -0.55 -9.0 -0.44 1.56e-17 Bipolar disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01272058 chr19:40926777 NA 0.49 6.58 0.34 1.78e-10 Lung function (FEV1/FVC); LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg18306943 chr3:40428807 ENTPD3 0.4 7.01 0.35 1.29e-11 Renal cell carcinoma; LIHC cis rs2153535 0.580 rs9505457 chr6:8479142 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs7618501 0.633 rs6772095 chr3:49978069 C/T cg24110177 chr3:50126178 RBM5 -0.48 -7.78 -0.39 8.7e-14 Intelligence (multi-trait analysis); LIHC cis rs3617 0.625 rs2245647 chr3:52862753 A/G cg11645453 chr3:52864694 ITIH4 0.22 5.95 0.31 6.58e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs208520 0.661 rs207099 chr6:66796373 A/C cg07460842 chr6:66804631 NA -0.85 -9.21 -0.45 3.37e-18 Exhaled nitric oxide output; LIHC cis rs7980687 0.628 rs2102949 chr12:123676763 G/A cg00376283 chr12:123451042 ABCB9 0.7 10.64 0.5 4.85e-23 Height;Educational attainment;Head circumference (infant); LIHC cis rs8103278 0.864 rs2070737 chr19:46282890 A/T cg14061069 chr19:46274453 DMPK -0.57 -9.05 -0.44 1.12e-17 Coronary artery disease; LIHC cis rs7799006 0.527 rs3779009 chr7:2203692 G/C cg02951883 chr7:2050386 MAD1L1 -0.48 -7.45 -0.37 7.63e-13 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs807029 0.533 rs3740487 chr10:102750783 C/A cg17130504 chr10:102756923 LZTS2 0.56 7.78 0.39 8.74e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs8060686 0.641 rs75909028 chr16:68089578 A/C cg09835421 chr16:68378352 PRMT7 -0.49 -5.77 -0.3 1.8e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs7927771 0.524 rs10838774 chr11:47856114 A/G cg20307385 chr11:47447363 PSMC3 0.77 11.49 0.53 4.61e-26 Subjective well-being; LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg20295408 chr7:1910781 MAD1L1 -0.43 -6.26 -0.32 1.15e-9 Bipolar disorder and schizophrenia; LIHC cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg06618935 chr21:46677482 NA -0.3 -5.81 -0.3 1.41e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1003719 0.751 rs55992706 chr21:38542749 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs10464366 0.544 rs12701697 chr7:39182165 C/T cg15212455 chr7:39170539 POU6F2 0.47 8.45 0.42 8.36e-16 IgG glycosylation; LIHC cis rs1577917 0.633 rs7770835 chr6:86608907 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.33 -0.37 1.71e-12 Response to antipsychotic treatment; LIHC cis rs17685 0.672 rs10952841 chr7:75778626 A/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17384381 0.953 rs12122816 chr1:85792384 C/T cg16011679 chr1:85725395 C1orf52 0.84 9.03 0.44 1.26e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs4803468 1.000 rs10422956 chr19:41901261 C/T cg14132834 chr19:41945861 ATP5SL -0.43 -6.42 -0.33 4.49e-10 Height; LIHC cis rs6442522 0.678 rs3773451 chr3:15510133 T/G cg16303742 chr3:15540471 COLQ 0.45 7.68 0.38 1.7e-13 Uric acid levels; LIHC cis rs10905065 0.965 rs10737019 chr10:5783733 G/A cg11519256 chr10:5708881 ASB13 0.46 6.11 0.31 2.66e-9 Menopause (age at onset); LIHC cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.89 -12.82 -0.57 5.53e-31 Alzheimer's disease; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.13 -0.31 2.49e-9 Total body bone mineral density; LIHC cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg10360323 chr17:41437877 NA 0.4 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg18279126 chr7:2041391 MAD1L1 0.38 6.41 0.33 4.89e-10 Bipolar disorder and schizophrenia; LIHC cis rs9768139 0.903 rs28503558 chr7:158119568 C/T cg25566285 chr7:158114605 PTPRN2 -0.26 -7.59 -0.38 3.04e-13 Calcium levels; LIHC cis rs6121246 0.909 rs6087778 chr20:30354142 G/A cg13852791 chr20:30311386 BCL2L1 0.95 9.7 0.46 8.02e-20 Mean corpuscular hemoglobin; LIHC cis rs9513627 1.000 rs73556181 chr13:100122092 G/A cg25919922 chr13:100150906 NA -0.8 -7.07 -0.36 8.77e-12 Obesity-related traits; LIHC cis rs11605275 0.892 rs16937352 chr11:20032010 G/C cg14835545 chr11:20032148 NAV2 -0.8 -7.38 -0.37 1.18e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs644799 0.965 rs499076 chr11:95546341 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.82 0.47 3.16e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.88 0.3 9.7e-9 Tonsillectomy; LIHC cis rs17685 0.712 rs4732578 chr7:75721532 A/G cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.37e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.91 -0.3 8.12e-9 Menopause (age at onset); LIHC cis rs7659604 0.537 rs6823818 chr4:122731699 G/C cg20573242 chr4:122745356 CCNA2 0.53 7.69 0.38 1.58e-13 Type 2 diabetes; LIHC cis rs6964587 0.934 rs7793861 chr7:91742728 C/G cg17063962 chr7:91808500 NA 1.01 19.45 0.72 2.9e-57 Breast cancer; LIHC cis rs6976053 0.518 rs144173 chr7:100416250 A/G cg03098644 chr7:100410630 EPHB4 -0.42 -6.78 -0.34 5.38e-11 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg09222892 chr1:25734099 RHCE -0.46 -8.47 -0.42 7.22e-16 Erythrocyte sedimentation rate; LIHC cis rs17685 0.753 rs1574107 chr7:75685047 A/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.32 -0.32 8.21e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.52 -0.38 4.85e-13 Lymphocyte counts; LIHC cis rs7772486 0.754 rs6932863 chr6:146021255 A/T cg13319975 chr6:146136371 FBXO30 0.41 6.84 0.35 3.76e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs35883536 0.647 rs1855630 chr1:101039979 C/G cg14515779 chr1:101123966 NA 0.45 6.37 0.33 6.13e-10 Monocyte count; LIHC trans rs11098499 0.909 rs9994810 chr4:120381590 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.66 0.46 1.1e-19 Corneal astigmatism; LIHC cis rs2559856 0.967 rs2695297 chr12:102082218 T/C cg12924262 chr12:102091054 CHPT1 0.49 7.79 0.39 7.92e-14 Blood protein levels; LIHC cis rs1552244 0.515 rs67626468 chr3:10161518 C/A cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs9818758 0.607 rs9850917 chr3:49286983 A/G cg07636037 chr3:49044803 WDR6 -0.79 -8.19 -0.4 5.34e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs1005277 0.579 rs1780130 chr10:38485378 T/A cg17830980 chr10:43048298 ZNF37B -0.52 -10.07 -0.48 4.52e-21 Extrinsic epigenetic age acceleration; LIHC cis rs28735056 0.904 rs72980087 chr18:77632194 G/A cg20368463 chr18:77673604 PQLC1 -0.38 -6.72 -0.34 7.5e-11 Schizophrenia; LIHC cis rs1866706 0.865 rs17488051 chr11:12861994 C/T cg25843174 chr11:12811716 TEAD1 -0.33 -6.92 -0.35 2.28e-11 Intelligence (multi-trait analysis); LIHC cis rs7897654 0.571 rs12767543 chr10:104631663 G/A cg15744005 chr10:104629667 AS3MT -0.37 -7.54 -0.38 4.23e-13 Schizophrenia; LIHC cis rs589448 0.967 rs2617834 chr12:69753365 T/C cg20891283 chr12:69753455 YEATS4 0.95 22.44 0.77 3.39e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs4746818 0.711 rs4745976 chr10:70845181 A/G cg11621586 chr10:70884670 VPS26A 0.62 8.96 0.44 2.07e-17 Left atrial antero-posterior diameter; LIHC cis rs9814567 1.000 rs4974483 chr3:134219001 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs61712019 0.724 rs11126614 chr2:77722736 G/A cg11252801 chr2:77748917 LRRTM4 0.56 7.73 0.39 1.2e-13 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22365063 chr1:231473646 C1orf124;EXOC8 -0.48 -7.04 -0.36 1.05e-11 Pancreatic cancer; LIHC cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC cis rs9341808 0.905 rs3805903 chr6:80975829 T/C cg08355045 chr6:80787529 NA 0.32 6.26 0.32 1.13e-9 Sitting height ratio; LIHC cis rs11077998 0.967 rs11657886 chr17:80516173 T/C cg10255544 chr17:80519551 FOXK2 0.49 8.86 0.43 4.29e-17 Reticulocyte fraction of red cells; LIHC cis rs8062405 1.000 rs56404918 chr16:28846840 T/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs61712019 1.000 rs2861076 chr2:77703418 A/G cg11252801 chr2:77748917 LRRTM4 0.51 7.81 0.39 6.95e-14 Schizophrenia; LIHC cis rs7772486 0.846 rs9376976 chr6:146355605 T/C cg23711669 chr6:146136114 FBXO30 0.66 11.76 0.54 4.95e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs11059919 1 rs11059919 chr12:129289190 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.7 -13.49 -0.59 1.52e-33 Systemic lupus erythematosus; LIHC cis rs2243480 0.615 rs34363376 chr7:65939536 T/C cg12463550 chr7:65579703 CRCP 0.59 5.92 0.3 7.93e-9 Diabetic kidney disease; LIHC cis rs7312774 0.618 rs4964501 chr12:107330079 C/T cg16260113 chr12:107380972 MTERFD3 -0.81 -10.59 -0.5 7.31e-23 Severe influenza A (H1N1) infection; LIHC cis rs3099143 1.000 rs2629034 chr15:77042240 G/A cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Recalcitrant atopic dermatitis; LIHC cis rs9419702 0.639 rs9419624 chr10:133534822 G/A cg04492858 chr10:133558786 NA 0.44 6.56 0.33 1.97e-10 Survival in rectal cancer; LIHC cis rs3096299 0.900 rs3114867 chr16:89428967 A/C cg06640241 chr16:89574553 SPG7 0.61 9.96 0.47 1.1e-20 Multiple myeloma (IgH translocation); LIHC trans rs11039798 0.582 rs1304193 chr11:48688588 C/T cg03929089 chr4:120376271 NA 0.53 6.13 0.31 2.36e-9 Axial length; LIHC cis rs1008375 1.000 rs10939746 chr4:17684951 A/G cg02297831 chr4:17616191 MED28 -0.43 -6.94 -0.35 1.95e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4631830 0.720 rs7090326 chr10:51503375 A/T cg20129853 chr10:51489980 NA -0.41 -9.01 -0.44 1.51e-17 Prostate-specific antigen levels; LIHC cis rs597539 0.652 rs654071 chr11:68653432 A/C cg04772025 chr11:68637568 NA 0.44 5.9 0.3 8.89e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2257205 0.667 rs8068677 chr17:56869386 G/A cg12560992 chr17:57184187 TRIM37 0.67 7.2 0.36 3.87e-12 Pancreatic cancer; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg27432699 chr2:27873401 GPN1 -0.49 -7.12 -0.36 6.24e-12 Total body bone mineral density; LIHC cis rs9916302 0.904 rs55660616 chr17:37684990 C/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.37 -0.59 4.35e-33 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00833344 chr2:150426294 MMADHC 0.42 6.45 0.33 3.86e-10 Pancreatic cancer; LIHC cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg03452623 chr4:187889614 NA -0.32 -8.31 -0.41 2.33e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs5758659 0.504 rs133367 chr22:42463366 A/G cg19513890 chr22:42538836 CYP2D7P1 0.3 5.79 0.3 1.56e-8 Cognitive function; LIHC cis rs7909074 1.000 rs12777258 chr10:45394961 A/G cg05187965 chr10:45406764 TMEM72 0.29 6.95 0.35 1.83e-11 Mean corpuscular volume; LIHC cis rs7208859 0.623 rs11651857 chr17:28926362 G/T cg14067834 chr17:29058358 SUZ12P 0.67 6.62 0.34 1.36e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1023500 0.551 rs2854837 chr22:42458481 G/A cg04733989 chr22:42467013 NAGA 0.65 9.15 0.44 5.13e-18 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08464520 chr19:56104287 FIZ1 0.43 6.26 0.32 1.15e-9 Longevity; LIHC cis rs918629 0.530 rs6889029 chr5:95251238 A/G cg10483112 chr5:95245456 ELL2 0.37 6.6 0.34 1.58e-10 IgG glycosylation; LIHC cis rs4474465 1.000 rs11237510 chr11:78173584 G/A cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs1348850 0.526 rs10930802 chr2:178460095 A/G cg27490568 chr2:178487706 NA 1.04 11.88 0.54 1.72e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10504229 0.610 rs6993531 chr8:58147283 A/G cg02290350 chr8:58132656 NA 0.44 9.28 0.45 2.02e-18 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.647 rs11072607 chr15:76908529 C/T cg23625390 chr15:77176239 SCAPER -0.54 -8.89 -0.43 3.7e-17 Blood metabolite levels; LIHC cis rs2075165 0.901 rs7522860 chr1:156275281 C/T cg10096929 chr1:156261403 TMEM79 0.35 6.15 0.32 2.17e-9 Tonsillectomy; LIHC cis rs6714710 0.603 rs13020776 chr2:98402753 T/A cg26665480 chr2:98280029 ACTR1B 0.45 6.38 0.33 5.65e-10 Posterior cortical atrophy and Alzheimer's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12465518 chr17:58308936 SCARNA20;USP32 0.44 6.07 0.31 3.44e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6912958 0.712 rs2246113 chr6:88410050 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.38 -6.62 -0.34 1.43e-10 Monocyte percentage of white cells; LIHC cis rs4407350 1.000 rs5765748 chr22:44925328 A/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.02 -0.31 4.44e-9 Intelligence (multi-trait analysis); LIHC cis rs7769051 1.000 rs7769051 chr6:133146796 G/T cg22852734 chr6:133119734 C6orf192 0.89 9.02 0.44 1.38e-17 Type 2 diabetes nephropathy; LIHC cis rs17253792 0.822 rs112418863 chr14:56114079 G/A cg01858014 chr14:56050164 KTN1 -0.7 -7.0 -0.35 1.36e-11 Putamen volume; LIHC cis rs898097 0.812 rs72859941 chr17:80837459 G/A cg15369054 chr17:80825471 TBCD 0.44 6.27 0.32 1.1e-9 Breast cancer; LIHC cis rs9611565 1.000 rs1109151 chr22:41752944 A/G cg03806693 chr22:41940476 POLR3H -0.49 -6.29 -0.32 9.67e-10 Vitiligo; LIHC cis rs9916302 0.851 rs12936996 chr17:37665554 A/G cg15445000 chr17:37608096 MED1 -0.38 -5.75 -0.3 1.95e-8 Glomerular filtration rate (creatinine); LIHC cis rs1419980 0.673 rs4883421 chr12:7774028 A/G cg14906510 chr12:7781169 NA 0.45 7.11 0.36 6.88e-12 HDL cholesterol levels; LIHC cis rs35110281 0.641 rs9978858 chr21:45085552 A/G cg04455712 chr21:45112962 RRP1B 0.53 8.57 0.42 3.63e-16 Mean corpuscular volume; LIHC cis rs8017423 1.000 rs769044 chr14:90671138 A/G cg14092571 chr14:90743983 NA -0.36 -5.77 -0.3 1.81e-8 Mortality in heart failure; LIHC cis rs711245 0.573 rs7570763 chr2:36800589 A/C cg10546459 chr2:36825355 FEZ2 -0.5 -6.11 -0.31 2.72e-9 Height; LIHC cis rs7715806 0.500 rs34355 chr5:74959970 G/A cg00601450 chr5:74908170 NA -0.68 -8.92 -0.43 2.92e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg06882758 chr19:58662330 ZNF329 0.92 6.85 0.35 3.54e-11 Cholesterol, total; LIHC cis rs7572733 0.515 rs6752458 chr2:198835106 G/T cg03934865 chr2:198174659 NA 0.46 6.76 0.34 5.8e-11 Dermatomyositis; LIHC cis rs7677751 0.806 rs7673027 chr4:55096180 T/A cg17187183 chr4:55093834 PDGFRA 0.68 8.52 0.42 5.06e-16 Corneal astigmatism; LIHC cis rs6952808 0.609 rs6950151 chr7:1953521 T/C cg04267008 chr7:1944627 MAD1L1 -0.63 -10.06 -0.48 4.98e-21 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs637571 0.726 rs689274 chr11:65665988 A/G cg26695010 chr11:65641043 EFEMP2 0.43 5.98 0.31 5.66e-9 Eosinophil percentage of white cells; LIHC cis rs9814567 0.752 rs9846111 chr3:134335034 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.56 -9.02 -0.44 1.34e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs78049276 0.736 rs6842241 chr4:148400819 C/A cg13149281 chr14:23389818 RBM23;PRMT5 -0.62 -8.17 -0.4 6.11e-15 Pulse pressure; LIHC cis rs832187 0.704 rs3774720 chr3:63951765 C/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.48 -6.73 -0.34 7.05e-11 Schizophrenia; LIHC cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg25894440 chr7:65020034 NA 0.55 6.21 0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs12291225 0.679 rs11023178 chr11:14310282 G/A cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.11e-31 Sense of smell; LIHC cis rs7100689 0.646 rs9420370 chr10:82073248 C/T cg01528321 chr10:82214614 TSPAN14 0.82 11.08 0.51 1.44e-24 Post bronchodilator FEV1; LIHC cis rs4899554 0.640 rs1569328 chr14:75741751 A/G cg18117039 chr14:75741733 NA -0.64 -9.77 -0.47 4.74e-20 Inflammatory bowel disease; LIHC cis rs2073300 1.000 rs6137975 chr20:23461778 A/G cg12062639 chr20:23401060 NAPB -0.75 -9.17 -0.44 4.53e-18 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs459571 0.792 rs55923934 chr9:136888233 C/G cg13789015 chr9:136890014 NCRNA00094 0.45 8.32 0.41 2.17e-15 Platelet distribution width; LIHC cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg11890956 chr21:40555474 PSMG1 1.05 15.11 0.63 7.4e-40 Cognitive function; LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs155076 0.938 rs9509633 chr13:21844482 G/C cg11317459 chr13:21872234 NA -1.18 -13.11 -0.58 4.12e-32 White matter hyperintensity burden; LIHC cis rs597539 0.652 rs636049 chr11:68667198 A/C cg04772025 chr11:68637568 NA 0.42 5.75 0.3 2.01e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg21448741 chr8:58168803 NA 0.33 6.0 0.31 4.95e-9 Developmental language disorder (linguistic errors); LIHC cis rs2204008 0.777 rs11179774 chr12:38219559 A/C cg26384229 chr12:38710491 ALG10B 0.86 10.75 0.5 2.1e-23 Bladder cancer; LIHC cis rs875971 1.000 rs1363055 chr7:65943275 A/G cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs7258950 1.000 rs7258950 chr19:11250139 C/T cg07962303 chr19:11253944 NA 0.59 6.95 0.35 1.85e-11 Cholesterol, total;LDL cholesterol; LIHC cis rs1003719 0.688 rs2000413 chr21:38539718 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.64 -0.5 5.15e-23 Eye color traits; LIHC cis rs2153535 0.601 rs9328487 chr6:8529378 G/C cg23788917 chr6:8435910 SLC35B3 0.63 9.02 0.44 1.37e-17 Motion sickness; LIHC cis rs3749237 0.595 rs4855864 chr3:49521974 C/T cg03060546 chr3:49711283 APEH 0.6 9.81 0.47 3.63e-20 Resting heart rate; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17930852 chr1:45957182 TESK2 -0.38 -6.03 -0.31 4.16e-9 Calcium levels; LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.522 rs289647 chr10:37968278 A/G cg25427524 chr10:38739819 LOC399744 -0.59 -11.26 -0.52 3.19e-25 Extrinsic epigenetic age acceleration; LIHC cis rs3020736 0.519 rs5996116 chr22:42517492 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.18 -0.32 1.78e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs11718455 0.585 rs11719257 chr3:43914854 A/T cg08738300 chr3:44038990 NA 0.37 6.31 0.32 8.55e-10 Coronary artery disease; LIHC cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC cis rs9814567 1.000 rs9819532 chr3:134288644 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs72960926 0.744 rs72952275 chr6:74926492 A/G cg07247405 chr1:2484626 LOC115110 0.56 6.62 0.34 1.36e-10 Metabolite levels (MHPG); LIHC cis rs11958404 0.789 rs78112793 chr5:157428226 A/G cg05962755 chr5:157440814 NA 0.96 10.59 0.5 7.36e-23 IgG glycosylation; LIHC cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg17554472 chr22:41940697 POLR3H -0.52 -5.9 -0.3 8.58e-9 Vitiligo; LIHC trans rs2243480 1.000 rs316327 chr7:65609201 G/T cg10756647 chr7:56101905 PSPH -1.1 -13.35 -0.59 4.97e-33 Diabetic kidney disease; LIHC cis rs2180341 0.960 rs1964130 chr6:127677391 C/G cg24812749 chr6:127587940 RNF146 1.02 14.29 0.61 1.2e-36 Breast cancer; LIHC cis rs11031096 0.727 rs7940013 chr11:4138304 C/T cg18678763 chr11:4115507 RRM1 -0.52 -7.94 -0.39 2.86e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.53 9.51 0.46 3.59e-19 Total body bone mineral density; LIHC cis rs10883723 0.773 rs1326193 chr10:104271674 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.64 0.56 2.67e-30 Allergic disease (asthma, hay fever or eczema); LIHC trans rs2727020 0.590 rs7949936 chr11:49378902 G/A cg18944383 chr4:111397179 ENPEP 0.32 7.17 0.36 4.67e-12 Coronary artery disease; LIHC cis rs2637266 0.783 rs10824437 chr10:78469493 C/T cg18941641 chr10:78392320 NA 0.27 5.86 0.3 1.09e-8 Pulmonary function; LIHC cis rs9359856 0.673 rs2039053 chr6:90303760 G/A cg13799429 chr6:90582589 CASP8AP2 0.57 6.23 0.32 1.37e-9 Bipolar disorder; LIHC cis rs796364 0.806 rs77853713 chr2:201006880 A/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs12477438 0.520 rs11677247 chr2:99756358 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.5 0.77 1.86e-69 Chronic sinus infection; LIHC cis rs10089 0.953 rs1432615 chr5:127395371 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.16e-11 Ileal carcinoids; LIHC cis rs10751667 0.560 rs7924794 chr11:962745 A/T ch.11.42038R chr11:967971 AP2A2 0.55 9.83 0.47 3.01e-20 Alzheimer's disease (late onset); LIHC trans rs7178375 1.000 rs28881289 chr15:31223955 A/G cg04373760 chr16:53404718 NA 0.59 7.57 0.38 3.57e-13 Hypertriglyceridemia; LIHC cis rs9942416 0.650 rs2640646 chr5:74977458 A/T cg19683494 chr5:74908142 NA -0.58 -7.57 -0.38 3.52e-13 Age-related disease endophenotypes; LIHC cis rs34779708 0.966 rs4934734 chr10:35434373 T/C cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6062302 0.522 rs11696202 chr20:62246292 G/C cg16989086 chr20:62203971 PRIC285 0.57 8.25 0.41 3.51e-15 Glioblastoma; LIHC cis rs8192917 1.000 rs6573910 chr14:25100882 A/G cg08766149 chr14:25103301 GZMB -0.33 -7.61 -0.38 2.76e-13 Vitiligo; LIHC cis rs4407350 1.000 rs4823330 chr22:44923080 G/A cg11695653 chr22:44894386 LDOC1L -0.37 -6.03 -0.31 4.3e-9 Intelligence (multi-trait analysis); LIHC cis rs7000551 0.725 rs2461489 chr8:22370253 G/A cg12081754 chr8:22256438 SLC39A14 0.43 6.8 0.34 4.77e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01999652 chr6:28220110 ZKSCAN4 0.46 6.99 0.35 1.47e-11 Cognitive function; LIHC cis rs7772486 0.875 rs1929523 chr6:146339989 T/A cg05347473 chr6:146136440 FBXO30 0.37 5.99 0.31 5.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.764 rs4896821 chr6:145896181 G/A cg23711669 chr6:146136114 FBXO30 0.63 11.33 0.52 1.72e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg15691649 chr6:25882328 NA 0.75 10.29 0.49 8.23e-22 Blood metabolite levels; LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg08677398 chr8:58056175 NA 0.4 6.27 0.32 1.08e-9 Developmental language disorder (linguistic errors); LIHC cis rs2224391 0.911 rs9504368 chr6:5261460 A/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs1639906 0.965 rs1639909 chr7:2233045 A/C cg02951883 chr7:2050386 MAD1L1 -0.46 -6.35 -0.32 6.77e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7107174 0.901 rs990706 chr11:78135704 C/T cg02023728 chr11:77925099 USP35 0.37 6.63 0.34 1.28e-10 Testicular germ cell tumor; LIHC trans rs61931739 0.500 rs11053212 chr12:34466116 T/G cg26384229 chr12:38710491 ALG10B 0.78 9.56 0.46 2.39e-19 Morning vs. evening chronotype; LIHC cis rs10911251 0.546 rs3359 chr1:183112041 G/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.66 0.5 4.1000000000000003e-23 Colorectal cancer; LIHC cis rs10927875 0.632 rs6677321 chr1:16149301 A/C cg07117364 chr1:16154769 NA -0.39 -6.96 -0.35 1.77e-11 Dilated cardiomyopathy; LIHC cis rs6684514 1.000 rs3806407 chr1:156251742 T/C cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs875971 0.545 rs1267814 chr7:66044409 G/A cg11764359 chr7:65958608 NA -0.62 -8.93 -0.44 2.58e-17 Aortic root size; LIHC cis rs79057730 0.527 rs34519158 chr7:811114 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.79 9.06 0.44 1.04e-17 Initial pursuit acceleration; LIHC cis rs1451375 1.000 rs2329340 chr7:50620229 C/T cg14593290 chr7:50529359 DDC 0.42 6.94 0.35 2.03e-11 Malaria; LIHC cis rs8060686 0.641 rs75796305 chr16:68208791 A/G cg05110241 chr16:68378359 PRMT7 -0.57 -6.52 -0.33 2.47e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs9457247 0.602 rs17615336 chr6:167506734 A/G cg07741184 chr6:167504864 NA 0.35 8.1 0.4 9.89e-15 Crohn's disease; LIHC trans rs6952808 0.656 rs73048919 chr7:2103637 C/A cg04565464 chr8:145669602 NFKBIL2 0.38 6.18 0.32 1.85e-9 Bipolar disorder and schizophrenia; LIHC cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg24884572 chr19:58661833 ZNF329 0.97 7.48 0.38 6.13e-13 Cholesterol, total; LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg00656387 chr3:40428638 ENTPD3 0.49 8.34 0.41 1.81e-15 Renal cell carcinoma; LIHC cis rs34779708 0.733 rs59287215 chr10:35543994 C/T cg03585969 chr10:35415529 CREM 0.76 11.02 0.51 2.18e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10493773 0.618 rs17394091 chr1:86075098 A/G cg17807903 chr1:86174739 ZNHIT6 -0.49 -6.86 -0.35 3.21e-11 Urate levels in overweight individuals; LIHC cis rs6121246 0.909 rs6060923 chr20:30336655 A/C cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg15472170 chr1:12012720 PLOD1 0.38 6.79 0.34 5.01e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs4911259 0.552 rs13038017 chr20:31467551 T/C cg13636640 chr20:31349939 DNMT3B -0.62 -10.85 -0.51 9.07e-24 Inflammatory bowel disease; LIHC cis rs17685 0.753 rs8200 chr7:75696606 C/G cg04592579 chr7:75616294 TMEM120A -0.4 -6.96 -0.35 1.75e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7223966 1.000 rs11657306 chr17:61704822 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.74 0.34 6.94e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4819052 0.851 rs7281263 chr21:46695606 T/C cg22633049 chr21:46681294 NA -0.38 -6.32 -0.32 8.16e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg21724239 chr8:58056113 NA 0.47 6.17 0.32 1.96e-9 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.908 rs7695996 chr4:120322033 C/T cg09307838 chr4:120376055 NA 0.77 11.96 0.54 8.81e-28 Corneal astigmatism; LIHC cis rs3008870 0.709 rs62883160 chr1:67392889 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.7 0.5 3.19e-23 Lymphocyte percentage of white cells; LIHC cis rs7677751 0.806 rs7673853 chr4:55096606 T/C cg17187183 chr4:55093834 PDGFRA 0.67 8.47 0.42 7.35e-16 Corneal astigmatism; LIHC trans rs6600671 0.899 rs11249432 chr1:121283476 T/A cg09829573 chr1:144692074 NBPF9 -0.4 -7.25 -0.36 2.86e-12 Hip geometry; LIHC cis rs6815814 0.731 rs10776483 chr4:38775040 A/G cg06935464 chr4:38784597 TLR10 0.38 5.94 0.31 7.12e-9 Breast cancer; LIHC cis rs7772486 0.597 rs9386136 chr6:146158300 A/T cg13319975 chr6:146136371 FBXO30 -0.57 -9.09 -0.44 8.01e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs4650994 0.593 rs2811302 chr1:178552875 C/T cg05350800 chr1:178550844 NA -0.34 -7.76 -0.39 9.71e-14 HDL cholesterol levels;HDL cholesterol; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24923311 chr20:30697516 TM9SF4 0.43 6.23 0.32 1.41e-9 Cognitive function; LIHC cis rs9814567 1.000 rs7611828 chr3:134250325 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7772486 0.790 rs9376971 chr6:146259505 C/T cg13319975 chr6:146136371 FBXO30 0.35 5.72 0.3 2.27e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg13409248 chr3:40428643 ENTPD3 0.47 7.79 0.39 8.02e-14 Renal cell carcinoma; LIHC cis rs3106136 0.837 rs2289186 chr4:95255637 T/G cg11021082 chr4:95130006 SMARCAD1 0.4 7.15 0.36 5.27e-12 Capecitabine sensitivity; LIHC cis rs9420 0.961 rs7936998 chr11:57639017 G/A cg19752551 chr11:57585705 CTNND1 -0.5 -6.9 -0.35 2.49e-11 Schizophrenia; LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.6 -8.64 -0.42 2.16e-16 Lymphocyte counts; LIHC cis rs1143633 0.509 rs2068777 chr2:113696126 A/G cg12858261 chr2:113808755 IL1F8 0.38 6.59 0.34 1.65e-10 Allergic disease (asthma, hay fever or eczema); LIHC cis rs425535 0.619 rs10938105 chr4:74826087 C/A cg02530824 chr4:74847766 PF4 -0.37 -5.95 -0.31 6.57e-9 Blood protein levels; LIHC cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.27e-19 Initial pursuit acceleration; LIHC cis rs1577917 1.000 rs1018184 chr6:86648475 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.53 9.49 0.46 3.94e-19 Response to antipsychotic treatment; LIHC cis rs1005224 0.654 rs8005753 chr14:76136086 A/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.42 -5.83 -0.3 1.3e-8 Large artery stroke; LIHC cis rs7044106 0.791 rs10984995 chr9:123479210 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.72 0.39 1.3e-13 Hip circumference adjusted for BMI; LIHC cis rs4820539 1.000 rs885963 chr22:23460939 G/T cg14186256 chr22:23484241 RTDR1 0.96 20.4 0.74 4.35e-61 Bone mineral density; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg11618577 chr2:27665543 KRTCAP3 0.43 5.9 0.3 8.71e-9 Total body bone mineral density; LIHC cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC cis rs12477438 0.765 rs4374423 chr2:99662348 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs3008870 0.755 rs12562761 chr1:67396739 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.76 0.5 1.87e-23 Lymphocyte percentage of white cells; LIHC cis rs4906332 1.000 rs17617094 chr14:103893428 T/C cg04998671 chr14:104000505 TRMT61A -0.45 -6.26 -0.32 1.12e-9 Coronary artery disease; LIHC cis rs7523273 0.546 rs2796261 chr1:207888760 C/T cg22525895 chr1:207977042 MIR29B2 -0.53 -7.99 -0.4 2.14e-14 Schizophrenia; LIHC cis rs655641 0.859 rs654194 chr11:85700000 C/A cg09030501 chr11:85779252 PICALM -0.54 -6.32 -0.32 8.19e-10 Platelet count; LIHC cis rs10193935 0.901 rs6720837 chr2:42463173 A/T cg27598129 chr2:42591480 NA -0.71 -10.62 -0.5 5.64e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs1552244 0.882 rs13063098 chr3:10009919 G/A cg00149659 chr3:10157352 C3orf10 0.54 6.06 0.31 3.62e-9 Alzheimer's disease; LIHC cis rs711245 0.670 rs7560321 chr2:36822318 C/G cg01206211 chr2:36825736 FEZ2 -0.37 -6.66 -0.34 1.07e-10 Height; LIHC cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg00106254 chr7:1943704 MAD1L1 -0.41 -6.49 -0.33 3e-10 Bipolar disorder and schizophrenia; LIHC cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 9.27 0.45 2.08e-18 Platelet count; LIHC cis rs2204008 0.682 rs10880321 chr12:38370110 C/G cg26384229 chr12:38710491 ALG10B -0.53 -7.42 -0.37 9.16e-13 Bladder cancer; LIHC cis rs896854 0.812 rs2340586 chr8:95969261 G/A cg16049864 chr8:95962084 TP53INP1 -0.6 -11.48 -0.53 5.07e-26 Type 2 diabetes; LIHC cis rs11608355 0.545 rs2302707 chr12:109893797 G/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18011946 chr5:65440816 SFRS12 0.44 6.1 0.31 2.83e-9 Pancreatic cancer; LIHC cis rs2806561 0.894 rs1738475 chr1:23536891 C/G cg19743168 chr1:23544995 NA 0.42 7.97 0.4 2.39e-14 Height; LIHC cis rs7520050 0.933 rs6661163 chr1:46255004 A/G cg03146154 chr1:46216737 IPP -0.37 -5.92 -0.3 7.8e-9 Red blood cell count;Reticulocyte count; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg05484376 chr2:27715224 FNDC4 0.38 6.46 0.33 3.57e-10 Total body bone mineral density; LIHC cis rs4820294 0.516 rs12627943 chr22:38096334 C/G cg10587741 chr22:38071170 LGALS1 0.68 9.43 0.45 6.42e-19 Fat distribution (HIV); LIHC cis rs12602486 1.000 rs2285952 chr17:42268595 G/A cg13607699 chr17:42295918 UBTF -0.76 -6.42 -0.33 4.65e-10 Glycated hemoglobin levels; LIHC cis rs67311347 1.000 rs9841335 chr3:40475858 G/A cg24209194 chr3:40518798 ZNF619 0.49 7.37 0.37 1.32e-12 Renal cell carcinoma; LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs4555082 0.872 rs7153832 chr14:105730563 G/T cg13114125 chr14:105738426 BRF1 -0.73 -9.76 -0.47 5.17e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg11644478 chr21:40555479 PSMG1 0.77 9.67 0.46 9.97e-20 Cognitive function; LIHC cis rs8114671 0.562 rs4911450 chr20:33512406 C/T cg07148914 chr20:33460835 GGT7 0.66 10.12 0.48 3.16e-21 Height; LIHC trans rs3749237 1.000 rs2291542 chr3:49751585 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.65 10.31 0.49 7.15e-22 Resting heart rate; LIHC cis rs34779708 0.966 rs35814343 chr10:35427714 G/T cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2832077 0.527 rs2738953 chr21:30238363 G/C cg03476357 chr21:30257390 N6AMT1 0.54 7.92 0.39 3.27e-14 Cognitive test performance; LIHC cis rs2153535 0.563 rs1737584 chr6:8536742 C/T cg07606381 chr6:8435919 SLC35B3 0.78 11.32 0.52 1.99e-25 Motion sickness; LIHC cis rs875971 0.830 rs4718358 chr7:65973668 T/C cg18876405 chr7:65276391 NA 0.37 6.67 0.34 1.03e-10 Aortic root size; LIHC cis rs2303759 0.709 rs10414921 chr19:49823047 C/T cg22590775 chr19:49891494 CCDC155 0.47 7.47 0.37 6.79e-13 Multiple sclerosis; LIHC cis rs11758351 1.000 rs74363821 chr6:26189524 G/C cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs6502050 0.835 rs12450189 chr17:80095128 A/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.59e-9 Life satisfaction; LIHC cis rs924607 1.000 rs2455331 chr5:643593 T/C cg04476341 chr5:669733 TPPP 0.39 8.79 0.43 7.64e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs60871478 0.704 rs62432895 chr7:822050 C/G cg04727924 chr7:799746 HEATR2 -0.58 -8.7 -0.43 1.44e-16 Cerebrospinal P-tau181p levels; LIHC cis rs2963155 1.000 rs2963155 chr5:142756004 C/T cg17617527 chr5:142782415 NR3C1 -0.51 -7.07 -0.36 8.69e-12 Breast cancer; LIHC cis rs1256061 0.624 rs1152577 chr14:64697485 T/G cg23250157 chr14:64679961 SYNE2 0.42 6.1 0.31 2.93e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs2243480 1.000 rs383402 chr7:65586653 A/C cg10756647 chr7:56101905 PSPH -1.03 -12.6 -0.56 3.71e-30 Diabetic kidney disease; LIHC trans rs1814175 0.645 rs1851869 chr11:49960552 T/C cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs7264396 0.676 rs6060730 chr20:34558503 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs75908454 1.000 rs77114281 chr6:169846419 G/A cg19338460 chr6:170058176 WDR27 -0.84 -7.39 -0.37 1.15e-12 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs919433 0.680 rs2565161 chr2:198285554 C/G cg03934865 chr2:198174659 NA 0.55 8.38 0.41 1.42e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7582720 1.000 rs115654617 chr2:203893999 C/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs35146811 0.771 rs6465762 chr7:99620554 G/A cg13334819 chr7:99746414 C7orf59 -0.56 -7.93 -0.39 3.1e-14 Coronary artery disease; LIHC cis rs55823223 0.564 rs58363746 chr17:73850819 C/T cg19302996 chr17:73780495 UNK -0.55 -6.82 -0.35 4.18e-11 Psoriasis; LIHC cis rs7617773 0.817 rs6801801 chr3:48326433 T/C cg11946769 chr3:48343235 NME6 0.87 11.41 0.52 9.38e-26 Coronary artery disease; LIHC cis rs55665837 0.701 rs12787709 chr11:14639257 G/A cg00085434 chr11:14927489 NA 0.43 5.88 0.3 9.55e-9 Vitamin D levels; LIHC cis rs2732480 0.577 rs2732457 chr12:48758379 A/G cg21466736 chr12:48725269 NA 0.71 10.72 0.5 2.67e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.09e-8 Electroencephalogram traits; LIHC cis rs6088580 0.634 rs3736762 chr20:33037336 C/T cg08999081 chr20:33150536 PIGU 0.67 13.3 0.58 7.93e-33 Glomerular filtration rate (creatinine); LIHC cis rs72653721 0.689 rs17697089 chr6:11065856 C/T cg13562911 chr6:11044106 ELOVL2 0.51 7.49 0.38 6.05e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs5769765 1.000 rs2295408 chr22:50261051 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.06 0.44 1.05e-17 Schizophrenia; LIHC cis rs9633740 0.504 rs1993484 chr10:82222698 T/C cg00277334 chr10:82204260 NA -0.61 -7.08 -0.36 8e-12 Post bronchodilator FEV1; LIHC cis rs7095944 0.584 rs4962691 chr10:126424137 C/T cg20435097 chr10:126320824 FAM53B 0.38 6.27 0.32 1.09e-9 Asthma; LIHC cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.13 -0.44 5.88e-18 Bipolar disorder; LIHC cis rs10493773 0.502 rs12066742 chr1:86081149 A/G cg17807903 chr1:86174739 ZNHIT6 -0.51 -8.01 -0.4 1.79e-14 Urate levels in overweight individuals; LIHC cis rs10792665 0.724 rs948183 chr11:82722300 C/T cg24227371 chr11:82718527 RAB30 -0.38 -9.3 -0.45 1.69e-18 Obesity-related traits; LIHC cis rs67460515 0.500 rs9812507 chr3:160723393 G/A cg17135325 chr3:160939158 NMD3 0.42 5.73 0.3 2.21e-8 Parkinson's disease; LIHC cis rs9467773 1.000 rs6922824 chr6:26553815 C/G cg09904177 chr6:26538194 HMGN4 -0.65 -13.9 -0.6 3.83e-35 Intelligence (multi-trait analysis); LIHC cis rs10838687 0.736 rs2242261 chr11:47266808 T/G cg25783544 chr11:47291846 MADD 0.46 5.89 0.3 9.29e-9 Proinsulin levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13434278 chr19:1941928 CSNK1G2 -0.55 -6.12 -0.31 2.57e-9 Systolic blood pressure; LIHC cis rs8180040 0.966 rs59586735 chr3:47518325 C/T cg16586182 chr3:47516702 SCAP 0.61 11.96 0.54 8.96e-28 Colorectal cancer; LIHC cis rs9916302 0.752 rs11078895 chr17:37401051 A/G cg07936489 chr17:37558343 FBXL20 -0.79 -11.48 -0.53 4.92e-26 Glomerular filtration rate (creatinine); LIHC cis rs7044106 0.708 rs10760113 chr9:123474050 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.68 0.38 1.64e-13 Hip circumference adjusted for BMI; LIHC cis rs3790844 0.955 rs3790848 chr1:200006111 C/A cg13229857 chr1:200006247 NR5A2 0.37 6.06 0.31 3.6e-9 Pancreatic cancer; LIHC cis rs9457247 1.000 rs408087 chr6:167398952 C/T cg12798992 chr6:167411361 FGFR1OP 0.61 10.26 0.49 1.02e-21 Crohn's disease; LIHC cis rs6754311 0.593 rs10202489 chr2:136494186 G/A cg15123519 chr2:136567270 LCT 0.42 8.2 0.41 5.02e-15 Mosquito bite size; LIHC cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg25364880 chr3:44379878 C3orf23 0.52 7.1 0.36 7.13e-12 Depressive symptoms; LIHC cis rs548181 0.668 rs579661 chr11:125474766 A/G cg03464685 chr11:125439445 EI24 0.92 9.86 0.47 2.4e-20 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs600806 0.850 rs10858086 chr1:109915075 C/A cg16275483 chr1:110013120 SYPL2 -0.47 -5.89 -0.3 9.44e-9 Intelligence (multi-trait analysis); LIHC cis rs738321 0.762 rs5995543 chr22:38579026 G/A cg25457927 chr22:38595422 NA -0.39 -9.35 -0.45 1.17e-18 Breast cancer; LIHC cis rs4820539 1.000 rs4822361 chr22:23482718 A/G cg21100191 chr22:23484243 RTDR1 -0.9 -16.76 -0.67 1.84e-46 Bone mineral density; LIHC cis rs4671458 0.802 rs72821624 chr2:63691920 A/G cg17519650 chr2:63277830 OTX1 -0.52 -5.95 -0.31 6.81e-9 Subjective well-being; LIHC cis rs7618501 0.633 rs4688758 chr3:50028385 G/A cg21467203 chr3:49911342 NA -0.43 -7.74 -0.39 1.17e-13 Intelligence (multi-trait analysis); LIHC cis rs864643 0.945 rs1355733 chr3:39562656 G/A cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs12995491 0.933 rs13008732 chr2:88528771 G/A cg24977027 chr2:88469347 THNSL2 -0.34 -5.88 -0.3 9.53e-9 Response to metformin (IC50); LIHC cis rs12762955 0.608 rs7922760 chr10:1156815 G/C cg18964960 chr10:1102726 WDR37 -0.49 -5.89 -0.3 9.39e-9 Response to angiotensin II receptor blocker therapy; LIHC cis rs208520 0.779 rs208451 chr6:66906155 G/A cg07460842 chr6:66804631 NA -0.7 -7.58 -0.38 3.24e-13 Exhaled nitric oxide output; LIHC trans rs1814175 0.647 rs10839394 chr11:49844747 T/C cg03929089 chr4:120376271 NA -0.88 -17.39 -0.69 5.48e-49 Height; LIHC cis rs6952808 0.771 rs10269191 chr7:1915731 A/G cg02951883 chr7:2050386 MAD1L1 -0.53 -7.85 -0.39 5.32e-14 Bipolar disorder and schizophrenia; LIHC cis rs1797081 0.934 rs1797077 chr10:16853252 C/T cg23933602 chr10:16859644 RSU1 1.04 21.26 0.75 1.55e-64 Platelet distribution width; LIHC cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg17554472 chr22:41940697 POLR3H 0.56 6.01 0.31 4.84e-9 Vitiligo; LIHC cis rs3008870 1.000 rs12044278 chr1:67460977 T/C cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg03122164 chr19:39421160 MRPS12;SARS2 -0.41 -6.05 -0.31 3.84e-9 Immature fraction of reticulocytes; LIHC cis rs2404602 0.618 rs12442266 chr15:76567142 T/C cg03037974 chr15:76606532 NA 0.89 23.01 0.78 1.97e-71 Blood metabolite levels; LIHC cis rs2153535 0.504 rs9328472 chr6:8470848 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg16145915 chr7:1198662 ZFAND2A -0.4 -10.19 -0.48 1.84e-21 Longevity;Endometriosis; LIHC cis rs2153535 0.525 rs1335644 chr6:8488041 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs12893668 0.616 rs58033365 chr14:104030901 T/C cg24130564 chr14:104152367 KLC1 -0.55 -8.91 -0.43 3.16e-17 Reticulocyte count; LIHC cis rs9790314 0.967 rs457272 chr3:161096746 A/G cg04691961 chr3:161091175 C3orf57 -0.45 -7.07 -0.36 8.61e-12 Morning vs. evening chronotype; LIHC cis rs9902453 0.868 rs11080118 chr17:28475379 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.63 -10.16 -0.48 2.23e-21 Coffee consumption (cups per day); LIHC cis rs6840360 0.532 rs4235221 chr4:152511193 C/T cg22705602 chr4:152727874 NA -0.32 -6.22 -0.32 1.43e-9 Intelligence (multi-trait analysis); LIHC cis rs3849570 0.961 rs7620240 chr3:81762787 G/T cg07356753 chr3:81810745 GBE1 -0.63 -10.45 -0.49 2.37e-22 Waist circumference;Body mass index; LIHC cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7923837 0.651 rs10882095 chr10:94394402 T/G cg25506282 chr10:94462361 NA 0.34 5.74 0.3 2.06e-8 Body mass index;Multiple sclerosis; LIHC cis rs12744310 1.000 rs34759578 chr1:41774350 G/A cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs950169 0.800 rs4099846 chr15:84956894 C/G cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.12e-11 Schizophrenia; LIHC cis rs7408868 1.000 rs10406754 chr19:15274201 T/A cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20440901 chr2:228582758 SLC19A3 -0.56 -7.0 -0.35 1.4e-11 Systolic blood pressure; LIHC cis rs637571 0.522 rs679581 chr11:65746653 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 8.96 0.44 2.09e-17 Eosinophil percentage of white cells; LIHC cis rs7618501 0.602 rs2301166 chr3:50148305 C/G cg21467203 chr3:49911342 NA 0.44 7.76 0.39 1.01e-13 Intelligence (multi-trait analysis); LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg02592271 chr2:27665507 KRTCAP3 -0.46 -6.41 -0.33 4.78e-10 Total body bone mineral density; LIHC cis rs4065321 0.609 rs8075668 chr17:38137623 C/T cg17467752 chr17:38218738 THRA -0.56 -9.52 -0.46 3.31e-19 White blood cell count (basophil);White blood cell count; LIHC cis rs7106204 0.925 rs3924745 chr11:24223001 G/A ch.11.24196551F chr11:24239977 NA 0.8 11.25 0.52 3.54e-25 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1023500 0.505 rs134888 chr22:42674281 C/T cg15557168 chr22:42548783 NA -0.37 -6.38 -0.33 5.74e-10 Schizophrenia; LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg10755058 chr3:40428713 ENTPD3 0.4 6.94 0.35 1.95e-11 Renal cell carcinoma; LIHC cis rs7618501 0.521 rs6774354 chr3:49961780 G/A cg24110177 chr3:50126178 RBM5 -0.56 -8.82 -0.43 5.78e-17 Intelligence (multi-trait analysis); LIHC trans rs4714291 0.698 rs2983144 chr6:40046724 G/A cg02267698 chr19:7991119 CTXN1 -0.4 -6.74 -0.34 6.89e-11 Strep throat; LIHC cis rs2274273 0.774 rs9323278 chr14:55541574 C/G cg01864836 chr14:55583639 NA -0.37 -6.35 -0.32 6.94e-10 Protein biomarker; LIHC trans rs877282 0.891 rs11253393 chr10:788824 G/T cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.97 -0.31 5.92e-9 Colorectal cancer; LIHC trans rs1814175 0.646 rs10839335 chr11:49715265 G/T cg18944383 chr4:111397179 ENPEP 0.27 6.78 0.34 5.32e-11 Height; LIHC cis rs8017423 0.838 rs11845950 chr14:90723962 T/A cg14092571 chr14:90743983 NA -0.39 -6.16 -0.32 2.02e-9 Mortality in heart failure; LIHC cis rs8078723 0.668 rs4239225 chr17:38127112 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.55 -9.1 -0.44 7.49e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs11098499 0.542 rs7677836 chr4:120310638 T/A cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs1003719 0.646 rs9985082 chr21:38501021 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.23 -0.52 4.09e-25 Eye color traits; LIHC cis rs5769707 0.609 rs135861 chr22:49998118 A/G cg01652190 chr22:50026171 C22orf34 -0.33 -7.21 -0.36 3.52e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2439831 0.681 rs540388 chr15:43606494 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.51 0.53 4.07e-26 Lung cancer in ever smokers; LIHC cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg16822855 chr3:40428330 ENTPD3 0.34 6.18 0.32 1.85e-9 Renal cell carcinoma; LIHC cis rs2180341 1.000 rs9401950 chr6:127655485 C/T cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs17685 0.736 rs4732594 chr7:75753273 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9513627 1.000 rs7317330 chr13:100119876 T/G cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC trans rs61931739 0.500 rs11053199 chr12:34450534 C/T cg26384229 chr12:38710491 ALG10B -0.64 -8.19 -0.4 5.17e-15 Morning vs. evening chronotype; LIHC cis rs17106184 1.000 rs72898971 chr1:50971408 A/G cg07174182 chr1:51127561 FAF1 -0.64 -6.76 -0.34 6.13e-11 Type 2 diabetes; LIHC cis rs7089973 0.604 rs2420066 chr10:116583897 A/G cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs926392 0.572 rs6129158 chr20:37673967 A/G cg16355469 chr20:37678765 NA 0.53 8.66 0.42 1.89e-16 Dialysis-related mortality; LIHC trans rs1814175 0.645 rs847635 chr11:49923323 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs881375 0.678 rs10739581 chr9:123696871 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 6.15 0.32 2.13e-9 Rheumatoid arthritis; LIHC cis rs7772486 0.875 rs9390377 chr6:146386932 G/A cg23711669 chr6:146136114 FBXO30 0.66 11.43 0.53 7.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs950169 0.922 rs62028133 chr15:84919375 A/C cg12863693 chr15:85201151 NMB 0.41 5.83 0.3 1.31e-8 Schizophrenia; LIHC cis rs35110281 0.748 rs4997353 chr21:45002329 A/C cg01579765 chr21:45077557 HSF2BP -0.35 -6.68 -0.34 9.46e-11 Mean corpuscular volume; LIHC cis rs250677 0.687 rs250674 chr5:148438597 A/G cg12140854 chr5:148520817 ABLIM3 0.44 6.13 0.31 2.37e-9 Breast cancer; LIHC cis rs477692 0.905 rs576560 chr10:131420697 C/A cg05714579 chr10:131428358 MGMT 0.49 8.31 0.41 2.22e-15 Response to temozolomide; LIHC cis rs9733 0.536 rs6661415 chr1:150635869 G/A cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs10256972 0.626 rs62433138 chr7:1050877 T/C cg07308232 chr7:1071921 C7orf50 -0.39 -6.12 -0.31 2.56e-9 Longevity;Endometriosis; LIHC cis rs1008375 1.000 rs1860596 chr4:17660082 C/T cg02297831 chr4:17616191 MED28 0.5 7.61 0.38 2.72e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3816788 0.792 rs7013323 chr8:21869024 C/G cg17168535 chr8:21777572 XPO7 0.57 8.96 0.44 2.06e-17 Lung cancer in ever smokers; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg06021753 chr8:22102407 POLR3D -0.62 -6.18 -0.32 1.82e-9 Obesity-related traits; LIHC cis rs3820068 0.554 rs60233444 chr1:15921330 A/C cg17385448 chr1:15911702 AGMAT 0.34 5.87 0.3 1.01e-8 Systolic blood pressure; LIHC cis rs7772486 0.790 rs9497431 chr6:146248177 T/C cg23711669 chr6:146136114 FBXO30 -0.71 -12.4 -0.56 2.03e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 0.755 rs4787457 chr16:28555400 A/G cg16576597 chr16:28551801 NUPR1 0.49 7.76 0.39 9.79e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6542838 0.611 rs1976766 chr2:99522754 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.57 -0.33 1.83e-10 Fear of minor pain; LIHC cis rs11822910 0.953 rs11827928 chr11:57197890 A/G cg00522883 chr11:57194120 SLC43A3 0.7 8.4 0.41 1.2e-15 Platelet distribution width; LIHC cis rs11758351 0.660 rs77130538 chr6:26210723 T/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.26 0.37 2.59e-12 Gout;Renal underexcretion gout; LIHC trans rs8022179 0.580 rs58153827 chr14:103844630 G/A cg17675199 chr6:35436792 RPL10A -0.38 -7.38 -0.37 1.22e-12 Monocyte count; LIHC cis rs4631830 0.869 rs4131357 chr10:51537292 C/A cg20129853 chr10:51489980 NA -0.4 -8.66 -0.42 1.92e-16 Prostate-specific antigen levels; LIHC cis rs57590327 0.555 rs7634258 chr3:81799100 T/C cg07356753 chr3:81810745 GBE1 -0.57 -8.8 -0.43 6.88e-17 Extraversion; LIHC cis rs611744 0.647 rs864166 chr8:109249300 C/G cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs9296092 0.538 rs112113649 chr6:33524529 A/G cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.7e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs79149102 0.579 rs12594117 chr15:75323648 C/G cg16226627 chr15:75307476 SCAMP5 0.54 9.74 0.47 5.98e-20 Lung cancer; LIHC cis rs9486715 0.758 rs2971610 chr6:97027380 C/T cg06623918 chr6:96969491 KIAA0776 -0.87 -15.73 -0.65 2.38e-42 Headache; LIHC cis rs7100689 0.599 rs946892 chr10:82127551 C/T cg00277334 chr10:82204260 NA -0.56 -7.04 -0.36 1.06e-11 Post bronchodilator FEV1; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg24151027 chr5:77656318 SCAMP1 0.4 6.07 0.31 3.35e-9 Urinary tract infection frequency; LIHC cis rs67311347 0.866 rs3214006 chr3:40352134 C/T cg18306943 chr3:40428807 ENTPD3 0.35 5.84 0.3 1.18e-8 Renal cell carcinoma; LIHC cis rs9611565 0.506 rs1883825 chr22:41703408 A/G cg03806693 chr22:41940476 POLR3H -0.73 -8.51 -0.42 5.43e-16 Vitiligo; LIHC cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg11502198 chr6:26597334 ABT1 -0.63 -10.1 -0.48 3.57e-21 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02580404 chr16:19729857 C16orf88;IQCK 0.39 6.19 0.32 1.76e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10751667 0.643 rs7394524 chr11:933865 T/C ch.11.42038R chr11:967971 AP2A2 0.53 9.58 0.46 2.01e-19 Alzheimer's disease (late onset); LIHC cis rs2637030 0.559 rs423014 chr5:52894598 A/G cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.24e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs4906332 1.000 rs12879663 chr14:103874215 A/G cg19000871 chr14:103996768 TRMT61A -0.42 -7.2 -0.36 3.96e-12 Coronary artery disease; LIHC cis rs28595532 0.668 rs56410164 chr4:119331625 A/G cg21605333 chr4:119757512 SEC24D 1.06 8.55 0.42 4.25e-16 Cannabis dependence symptom count; LIHC cis rs11676348 0.846 rs7594532 chr2:219008000 T/C cg00012203 chr2:219082015 ARPC2 -0.58 -8.07 -0.4 1.23e-14 Ulcerative colitis; LIHC cis rs7116495 0.881 rs1892921 chr11:71702138 G/A cg26138937 chr11:71823887 C11orf51 -0.82 -8.35 -0.41 1.75e-15 Severe influenza A (H1N1) infection; LIHC cis rs9457247 0.765 rs12212247 chr6:167413539 T/C cg23791538 chr6:167370224 RNASET2 -0.51 -7.77 -0.39 9.22e-14 Crohn's disease; LIHC cis rs7577696 0.554 rs34835885 chr2:32325414 G/A cg02381751 chr2:32503542 YIPF4 -0.45 -6.06 -0.31 3.63e-9 Inflammatory biomarkers; LIHC cis rs4561483 0.801 rs33649 chr16:11979608 G/C cg08843971 chr16:11963173 GSPT1 -0.44 -8.55 -0.42 4.15e-16 Testicular germ cell tumor; LIHC trans rs2243480 1.000 rs35396113 chr7:65495461 C/T cg10756647 chr7:56101905 PSPH 1.08 13.33 0.58 5.93e-33 Diabetic kidney disease; LIHC cis rs77633900 0.614 rs7162982 chr15:76961559 G/A cg21673338 chr15:77095150 SCAPER 0.44 7.02 0.36 1.18e-11 Non-glioblastoma glioma;Glioma; LIHC trans rs2727020 0.521 rs10839299 chr11:49573981 C/T cg03929089 chr4:120376271 NA -0.7 -10.26 -0.49 1e-21 Coronary artery disease; LIHC cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg13047869 chr3:10149882 C3orf24 0.5 6.08 0.31 3.23e-9 Alzheimer's disease; LIHC cis rs7116495 0.609 rs73543643 chr11:71835596 C/T cg10381502 chr11:71823885 C11orf51 1.06 9.3 0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs10751667 0.666 rs7936830 chr11:959686 A/G ch.11.42038R chr11:967971 AP2A2 0.56 10.08 0.48 4.14e-21 Alzheimer's disease (late onset); LIHC cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg19318889 chr4:1322082 MAEA 0.64 10.38 0.49 3.94e-22 Longevity; LIHC cis rs12464559 0.522 rs12472627 chr2:152633114 C/T cg01189475 chr2:152685088 ARL5A 0.66 8.39 0.41 1.29e-15 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs9486719 1.000 rs2472897 chr6:96870569 G/T cg06623918 chr6:96969491 KIAA0776 0.7 6.81 0.35 4.44e-11 Migraine;Coronary artery disease; LIHC cis rs7647973 0.626 rs11720705 chr3:49753788 A/G cg03060546 chr3:49711283 APEH 0.6 6.83 0.35 3.82e-11 Menarche (age at onset); LIHC trans rs7395555 1.000 rs4945404 chr11:80077022 G/T cg06295071 chr21:33766731 URB1 -0.42 -6.24 -0.32 1.3e-9 Response to antipsychotic treatment; LIHC cis rs644799 0.526 rs530914 chr11:95632156 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.59 9.22 0.45 3.06e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6684514 0.922 rs12037778 chr1:156284864 A/G cg16558208 chr1:156270281 VHLL 0.55 10.36 0.49 4.85e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9303401 1.000 rs6503882 chr17:56915761 T/C cg05425664 chr17:57184151 TRIM37 -0.53 -7.46 -0.37 7.11e-13 Cognitive test performance; LIHC cis rs1577917 0.560 rs12193777 chr6:86246709 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.45 0.42 8.29e-16 Response to antipsychotic treatment; LIHC cis rs11122272 0.735 rs2256908 chr1:231506557 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs67460515 0.527 rs34221255 chr3:160854123 T/C cg03342759 chr3:160939853 NMD3 -0.58 -8.34 -0.41 1.89e-15 Parkinson's disease; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg19635926 chr16:89946313 TCF25 0.48 6.46 0.33 3.67e-10 Skin colour saturation; LIHC trans rs3812049 0.667 rs6888037 chr5:127406259 G/T cg16011800 chr17:1958478 HIC1 -0.51 -7.19 -0.36 4.14e-12 Lymphocyte counts;Red cell distribution width; LIHC cis rs2580764 0.540 rs10210840 chr2:55226009 G/A cg09592903 chr2:55203963 RTN4 -0.7 -12.95 -0.57 1.75e-31 Mean platelet volume; LIHC cis rs8103278 1.000 rs9807819 chr19:46239598 C/T cg11657440 chr19:46296263 DMWD -0.56 -9.22 -0.45 3.21e-18 Coronary artery disease; LIHC cis rs11098499 0.863 rs3775847 chr4:120447642 A/C cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg03806693 chr22:41940476 POLR3H -1.09 -12.46 -0.56 1.21e-29 Vitiligo; LIHC cis rs3749237 0.595 rs3870337 chr3:49557095 G/T cg03060546 chr3:49711283 APEH 0.6 9.77 0.47 4.93e-20 Resting heart rate; LIHC cis rs2303759 0.676 rs10426452 chr19:49907690 G/A cg22590775 chr19:49891494 CCDC155 0.47 7.77 0.39 9.33e-14 Multiple sclerosis; LIHC cis rs2153535 0.580 rs1932282 chr6:8477330 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs6503525 0.628 rs62068171 chr17:38103242 G/A cg17467752 chr17:38218738 THRA 0.42 6.82 0.35 4.15e-11 Asthma; LIHC cis rs262150 0.851 rs2527224 chr7:158769198 G/A cg19418458 chr7:158789849 NA -0.38 -6.69 -0.34 8.95e-11 Facial morphology (factor 20); LIHC cis rs3736485 0.934 rs1902593 chr15:51882080 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10744422 1.000 rs7959441 chr12:123363825 C/T cg07706471 chr12:123319906 HIP1R -0.55 -6.87 -0.35 3.01e-11 Schizophrenia; LIHC trans rs1814175 0.817 rs12290508 chr11:49621037 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -22.74 -0.78 2.2e-70 Height; LIHC cis rs6701037 0.566 rs1014555 chr1:175134249 C/T cg00321850 chr1:175162397 KIAA0040 0.46 7.6 0.38 2.88e-13 Alcohol dependence; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg14354430 chr9:136911493 BRD3 0.42 6.24 0.32 1.32e-9 Alopecia areata; LIHC cis rs1401999 1.000 rs10937158 chr3:183708439 T/C cg05044414 chr3:183734942 ABCC5 0.33 5.94 0.31 6.88e-9 Anterior chamber depth; LIHC cis rs11971779 0.680 rs3924296 chr7:139041927 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2204008 0.837 rs11168334 chr12:37961768 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.78 0.3 1.65e-8 Bladder cancer; LIHC cis rs11676348 0.808 rs1008563 chr2:219026888 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.45 -5.73 -0.3 2.26e-8 Ulcerative colitis; LIHC cis rs2303745 0.544 rs6512181 chr19:17399213 T/G cg04248312 chr19:17393744 ANKLE1 -0.73 -12.07 -0.55 3.51e-28 Systemic lupus erythematosus; LIHC cis rs1559088 0.573 rs1270591 chr19:33622942 C/T cg27124370 chr19:33622961 WDR88 -0.62 -9.71 -0.46 7.82e-20 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1144333 0.655 rs931506 chr1:76401349 T/C cg22875332 chr1:76189707 ACADM 0.41 6.22 0.32 1.42e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs9916302 0.851 rs11078907 chr17:37662954 C/T cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg22105103 chr4:187893119 NA 0.35 8.82 0.43 6.11e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs10744422 0.920 rs3896871 chr12:123333610 G/T cg25930673 chr12:123319894 HIP1R -0.93 -12.35 -0.56 3.04e-29 Schizophrenia; LIHC cis rs2153535 0.601 rs9406160 chr6:8464907 A/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04877780 chr17:80710066 TBCD -0.53 -6.45 -0.33 3.82e-10 Systolic blood pressure; LIHC cis rs4728302 0.869 rs13221033 chr7:133617487 T/A cg10665199 chr7:133106180 EXOC4 0.37 6.33 0.32 7.72e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs4919694 1.000 rs12242000 chr10:104702413 A/C cg04362960 chr10:104952993 NT5C2 1.13 8.8 0.43 6.86e-17 Arsenic metabolism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00552226 chr2:70475288 TIA1 0.54 7.36 0.37 1.35e-12 Pancreatic cancer; LIHC cis rs9921222 0.500 rs11645742 chr16:367516 C/T cg12437481 chr16:420112 MRPL28 -0.65 -8.73 -0.43 1.13e-16 Bone mineral density (spine);Bone mineral density; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg09302904 chr17:62340561 TEX2 -0.48 -6.2 -0.32 1.64e-9 Lung cancer in ever smokers; LIHC cis rs11190604 1.000 rs7477246 chr10:102261538 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.17 0.4 5.94e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1348850 0.914 rs7604673 chr2:178392346 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.86 13.49 0.59 1.49e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs748404 0.660 rs2467741 chr15:43742626 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.14 0.36 5.5e-12 Lung cancer; LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg02782426 chr3:40428986 ENTPD3 0.34 6.31 0.32 8.87e-10 Renal cell carcinoma; LIHC cis rs769267 0.930 rs9917108 chr19:19572785 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.95 0.31 6.6e-9 Tonsillectomy; LIHC cis rs8027181 0.839 rs8024986 chr15:73024868 A/G cg25632853 chr15:73088954 NA -0.36 -5.92 -0.3 7.76e-9 Triglyceride levels; LIHC cis rs3770081 1.000 rs60981340 chr2:86177046 G/T cg01119172 chr2:86362222 SNORD94;PTCD3 0.39 5.83 0.3 1.27e-8 Facial emotion recognition (sad faces); LIHC cis rs9911578 1.000 rs12940681 chr17:56933622 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.68 0.69 3.9e-50 Intelligence (multi-trait analysis); LIHC cis rs6748734 0.817 rs10182575 chr2:241806690 C/T cg09990169 chr2:241835740 C2orf54 -0.67 -10.61 -0.5 6.47e-23 Urinary metabolites; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13093793 chr14:35099518 SNX6 0.47 6.62 0.34 1.41e-10 Lung function (FEV1/FVC); LIHC cis rs116095464 0.558 rs6866776 chr5:264495 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs4638749 0.677 rs7581595 chr2:108847885 A/G cg25838818 chr2:108905173 SULT1C2 -0.41 -7.27 -0.37 2.53e-12 Blood pressure; LIHC trans rs1005277 0.563 rs2800550 chr10:38482929 T/C cg23533926 chr12:111358616 MYL2 -0.32 -6.12 -0.31 2.61e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2228479 0.850 rs2238527 chr16:89840708 C/A cg04013166 chr16:89971882 TCF25 0.53 6.67 0.34 1.04e-10 Skin colour saturation; LIHC cis rs919433 0.713 rs1455653 chr2:198478320 G/A cg10820045 chr2:198174542 NA 0.51 7.99 0.4 2.03e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg26752003 chr8:145688521 CYHR1 0.65 10.4 0.49 3.53e-22 Age at first birth; LIHC cis rs11673344 0.764 rs569371 chr19:37453997 A/G cg27390819 chr19:37464633 NA -0.51 -6.23 -0.32 1.37e-9 Obesity-related traits; LIHC cis rs6752107 1.000 rs6708373 chr2:234172846 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.56 0.42 3.89e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg22907277 chr7:1156413 C7orf50 0.58 8.82 0.43 5.97e-17 Longevity;Endometriosis; LIHC cis rs8073060 0.586 rs225292 chr17:33926383 G/A cg20932281 chr17:33905541 PEX12 -0.57 -6.54 -0.33 2.21e-10 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs11792861 0.816 rs11790105 chr9:111731785 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 9.15 0.44 5.21e-18 Menarche (age at onset); LIHC cis rs7523273 0.568 rs55935450 chr1:208018779 T/A cg22525895 chr1:207977042 MIR29B2 -0.57 -6.41 -0.33 4.74e-10 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01002560 chr7:16460779 ISPD 0.55 7.01 0.35 1.26e-11 Hepatitis; LIHC cis rs7617773 0.963 rs6771787 chr3:48194242 C/T cg11946769 chr3:48343235 NME6 -0.66 -8.46 -0.42 7.79e-16 Coronary artery disease; LIHC cis rs4665809 1.000 rs4665817 chr2:26305167 G/A cg27170947 chr2:26402098 FAM59B -0.67 -8.26 -0.41 3.13e-15 Gut microbiome composition (summer); LIHC cis rs10779751 1.000 rs4845987 chr1:11306279 G/C cg08854313 chr1:11322531 MTOR 0.87 15.85 0.65 8.35e-43 Body mass index; LIHC cis rs7534824 0.625 rs6699653 chr1:101499162 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.23 0.36 3.2e-12 Refractive astigmatism; LIHC cis rs7772486 0.686 rs9390357 chr6:146129347 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.81 0.3 1.43e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7249142 0.512 rs12981160 chr19:19298099 T/A cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.36 -6.07 -0.31 3.35e-9 IgG glycosylation; LIHC cis rs11673344 0.864 rs11670216 chr19:37503428 G/C cg27390819 chr19:37464633 NA -0.51 -6.21 -0.32 1.57e-9 Obesity-related traits; LIHC cis rs7561273 0.565 rs6545275 chr2:24331860 A/G cg06627628 chr2:24431161 ITSN2 -0.44 -5.89 -0.3 9.14e-9 Quantitative traits; LIHC cis rs1419980 0.730 rs11054916 chr12:7777083 T/C cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC cis rs763121 0.819 rs5757160 chr22:38989646 T/C cg21395723 chr22:39101663 GTPBP1 0.41 6.88 0.35 2.8e-11 Menopause (age at onset); LIHC cis rs4638749 0.677 rs115510885 chr2:108824365 C/T cg06795125 chr2:108905320 SULT1C2 -0.31 -6.04 -0.31 3.92e-9 Blood pressure; LIHC cis rs2979489 0.786 rs2915595 chr8:30402817 A/G cg26383811 chr8:30366931 RBPMS 0.71 12.58 0.56 4.47e-30 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs11122272 0.735 rs2572254 chr1:231512593 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.78e-23 Hemoglobin concentration; LIHC cis rs16828019 0.777 rs35044078 chr1:41474400 C/G cg03962019 chr1:41807865 NA 0.49 6.93 0.35 2.09e-11 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.731 rs12988076 chr2:136569848 C/A cg07305463 chr2:136567211 LCT 0.39 7.54 0.38 4.37e-13 Mosquito bite size; LIHC cis rs8141529 0.748 rs132531 chr22:29297365 C/T cg02153584 chr22:29168773 CCDC117 -0.52 -8.03 -0.4 1.63e-14 Lymphocyte counts; LIHC cis rs35306767 0.903 rs12254002 chr10:929133 A/G cg20503657 chr10:835505 NA -0.95 -11.15 -0.52 7.82e-25 Eosinophil percentage of granulocytes; LIHC cis rs10870270 0.956 rs10870293 chr10:133771413 G/A cg26149184 chr10:133730230 NA 0.46 7.26 0.37 2.56e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs675828 0.620 rs4772498 chr13:103350564 T/C cg16283183 chr3:45718805 LIMD1 -0.39 -6.05 -0.31 3.77e-9 Borderline personality disorder; LIHC cis rs854765 0.619 rs6502636 chr17:17983817 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.36 6.67 0.34 1.05e-10 Total body bone mineral density; LIHC cis rs7116495 0.609 rs4945392 chr11:71694645 C/T cg26138937 chr11:71823887 C11orf51 -1.28 -10.0 -0.48 8.22e-21 Severe influenza A (H1N1) infection; LIHC cis rs25645 0.800 rs11078935 chr17:38192137 T/G cg17467752 chr17:38218738 THRA -0.54 -9.25 -0.45 2.49e-18 Myeloid white cell count; LIHC cis rs12477438 0.501 rs12619780 chr2:99707307 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.07 0.61 8.69e-36 Chronic sinus infection; LIHC cis rs6088580 0.608 rs1205342 chr20:32921842 C/T cg08999081 chr20:33150536 PIGU -0.65 -12.41 -0.56 1.87e-29 Glomerular filtration rate (creatinine); LIHC cis rs4776059 0.724 rs11633933 chr15:52948357 T/C cg22715398 chr15:52968154 KIAA1370 -0.41 -6.47 -0.33 3.48e-10 Schizophrenia; LIHC cis rs5769707 0.521 rs739244 chr22:50060158 A/G cg07959070 chr22:50026188 C22orf34 -0.3 -7.17 -0.36 4.65e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7264396 0.790 rs2425160 chr20:34425968 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -10.46 -0.49 2.04e-22 Total cholesterol levels; LIHC cis rs2412488 0.853 rs7688853 chr4:54353215 C/T cg22241045 chr4:54363911 LNX1 0.41 6.83 0.35 3.89e-11 DNA methylation (variation); LIHC trans rs412658 0.668 rs7253490 chr19:22293706 A/C cg05197062 chr11:11642011 GALNTL4 0.42 6.06 0.31 3.68e-9 Telomere length; LIHC cis rs2180341 0.782 rs6569490 chr6:127729615 C/T cg24812749 chr6:127587940 RNF146 0.79 12.59 0.56 4.04e-30 Breast cancer; LIHC cis rs7223966 1.000 rs8081541 chr17:61812483 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.96 0.35 1.72e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9303401 0.659 rs62083362 chr17:56846464 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.32 0.58 6.47e-33 Cognitive test performance; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03276813 chr2:182757157 SSFA2 0.42 6.04 0.31 4.09e-9 Cognitive function; LIHC cis rs892961 0.932 rs7224442 chr17:75413439 A/G cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs17253792 0.822 rs76055105 chr14:56069127 A/G cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs6964587 1.000 rs6956596 chr7:91750107 T/G cg17063962 chr7:91808500 NA 1.02 19.6 0.73 7.06e-58 Breast cancer; LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg03188948 chr7:1209495 NA 0.46 6.52 0.33 2.49e-10 Longevity;Endometriosis; LIHC cis rs11098499 0.697 rs6832410 chr4:120296800 A/G cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg16822855 chr3:40428330 ENTPD3 0.35 6.38 0.33 5.91e-10 Renal cell carcinoma; LIHC cis rs2075371 0.897 rs1643033 chr7:134004662 T/C cg20476274 chr7:133979776 SLC35B4 0.68 11.31 0.52 2.14e-25 Mean platelet volume; LIHC cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg22800045 chr5:56110881 MAP3K1 0.67 8.62 0.42 2.48e-16 Initial pursuit acceleration; LIHC cis rs600806 0.888 rs3853500 chr1:109864269 T/C cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.92 -0.3 7.78e-9 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.913 rs12272917 chr11:68263370 T/C cg20283391 chr11:68216788 NA -0.52 -7.69 -0.38 1.53e-13 Total body bone mineral density; LIHC cis rs7772486 0.754 rs6915718 chr6:146100676 A/G cg13319975 chr6:146136371 FBXO30 0.4 6.35 0.32 6.97e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg11301795 chr4:187892539 NA 0.24 6.09 0.31 3.11e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs56146971 0.714 rs17804071 chr14:91852876 C/T cg16433844 chr14:91963127 SMEK1 -0.49 -5.86 -0.3 1.08e-8 Alzheimer disease and age of onset; LIHC cis rs9549328 0.921 rs9549623 chr13:113640293 G/A cg18289306 chr13:113640169 MCF2L 0.43 6.88 0.35 2.89e-11 Systolic blood pressure; LIHC cis rs7296418 0.663 rs4553407 chr12:123750748 G/C cg05973401 chr12:123451056 ABCB9 0.41 6.02 0.31 4.4e-9 Platelet count; LIHC cis rs644799 0.562 rs671320 chr11:95578780 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.63 10.23 0.48 1.31e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10876993 0.855 rs1678520 chr12:58049319 C/G cg15848620 chr12:58087721 OS9 -0.55 -7.42 -0.37 9.54e-13 Celiac disease or Rheumatoid arthritis; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg07332563 chr6:291687 DUSP22 -0.51 -7.03 -0.36 1.15e-11 Menopause (age at onset); LIHC trans rs8073060 0.586 rs72829927 chr17:34049992 A/G cg19694781 chr19:47549865 TMEM160 1.22 12.75 0.57 9.9e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs875971 0.862 rs801195 chr7:66026115 A/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.37e-9 Aortic root size; LIHC cis rs4851313 0.527 rs10183150 chr2:100939117 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.57 0.42 3.72e-16 Intelligence (multi-trait analysis); LIHC cis rs17376456 1.000 rs9968691 chr5:93509756 C/G cg25358565 chr5:93447407 FAM172A 1.1 10.01 0.48 7.28e-21 Diabetic retinopathy; LIHC cis rs2797160 0.651 rs1268093 chr6:126029235 C/T cg05901451 chr6:126070800 HEY2 0.52 9.54 0.46 2.71e-19 Endometrial cancer; LIHC cis rs4805272 0.539 rs1075733 chr19:29324460 C/T cg04546413 chr19:29218101 NA 0.43 7.29 0.37 2.2e-12 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC trans rs1005277 0.579 rs1780116 chr10:38526621 C/T cg23533926 chr12:111358616 MYL2 -0.33 -6.18 -0.32 1.82e-9 Extrinsic epigenetic age acceleration; LIHC cis rs9296092 0.517 rs62405949 chr6:33522800 G/A cg13560919 chr6:33536144 NA -0.39 -6.31 -0.32 8.5e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs9911578 1.000 rs11870671 chr17:56605360 A/G cg05425664 chr17:57184151 TRIM37 0.59 8.75 0.43 1e-16 Intelligence (multi-trait analysis); LIHC trans rs6108011 0.659 rs62202266 chr20:7580935 C/T cg13422339 chr21:47602486 C21orf56 0.52 6.07 0.31 3.41e-9 Hemostatic factors and hematological phenotypes; LIHC cis rs12602486 1.000 rs2285952 chr17:42268595 G/A cg08193365 chr17:42277699 NA 1.04 7.22 0.36 3.49e-12 Glycated hemoglobin levels; LIHC cis rs2795502 1.000 rs2795508 chr10:43353555 G/T cg27426351 chr10:43362370 NA 0.45 5.73 0.3 2.19e-8 Blood protein levels; LIHC cis rs1691799 0.867 rs1168338 chr12:66759369 T/C cg16791601 chr12:66731901 HELB -0.55 -13.2 -0.58 1.87e-32 White blood cell count (basophil); LIHC cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg12903224 chr12:29470962 FAR2 -0.38 -5.99 -0.31 5.41e-9 QT interval; LIHC trans rs9858542 1.000 rs4283605 chr3:49678651 A/G cg21659725 chr3:3221576 CRBN -0.57 -6.41 -0.33 4.91e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs34779708 0.643 rs4275563 chr10:35545286 G/A cg03585969 chr10:35415529 CREM 0.75 10.97 0.51 3.53e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3020736 0.500 rs9620026 chr22:42498578 C/T cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg09913183 chr17:42254507 C17orf65;ASB16 -0.69 -10.81 -0.5 1.31e-23 Total body bone mineral density; LIHC cis rs13040088 0.518 rs2427452 chr20:61577275 T/C cg23096297 chr20:61557774 DIDO1 -0.63 -8.7 -0.43 1.46e-16 Menopause (age at onset); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05191825 chr12:108956318 ISCU;SART3 -0.46 -6.16 -0.32 2.05e-9 Systolic blood pressure; LIHC cis rs17253792 0.822 rs12323476 chr14:56172722 C/T cg01858014 chr14:56050164 KTN1 0.59 6.92 0.35 2.29e-11 Putamen volume; LIHC cis rs7119038 0.818 rs4936444 chr11:118743338 A/G cg19308663 chr11:118741387 NA -0.46 -6.11 -0.31 2.65e-9 Sjögren's syndrome; LIHC cis rs763121 0.819 rs5757237 chr22:39073835 G/C cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.92e-12 Menopause (age at onset); LIHC cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg24549020 chr5:56110836 MAP3K1 0.5 6.49 0.33 3.09e-10 Initial pursuit acceleration; LIHC cis rs3806933 0.522 rs12522383 chr5:110455266 C/T cg04022379 chr5:110408740 TSLP 0.56 9.13 0.44 5.91e-18 Eosinophilic esophagitis; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg07677032 chr17:61819896 STRADA 0.42 6.26 0.32 1.14e-9 Prudent dietary pattern; LIHC cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg27170947 chr2:26402098 FAM59B 0.65 8.36 0.41 1.64e-15 Gut microbiome composition (summer); LIHC cis rs8060686 0.516 rs11075670 chr16:68288393 C/G cg05110241 chr16:68378359 PRMT7 -0.55 -6.59 -0.34 1.7e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs760762 0.660 rs6513714 chr20:39916401 A/T cg06424997 chr20:39929561 ZHX3 0.35 5.73 0.3 2.2e-8 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; LIHC cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7103648 0.966 rs1377416 chr11:47416746 C/T cg20307385 chr11:47447363 PSMC3 1.0 17.55 0.69 1.25e-49 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs7103648 0.669 rs7131262 chr11:47836302 T/A cg20307385 chr11:47447363 PSMC3 0.99 16.2 0.66 3.27e-44 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs7914558 1.000 rs7899084 chr10:104872547 A/T cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs61041384 0.661 rs79304919 chr12:123427951 C/T cg25930673 chr12:123319894 HIP1R 0.66 5.73 0.3 2.26e-8 Schizophrenia; LIHC cis rs2108622 0.711 rs113059233 chr19:15977368 G/A cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs1552244 0.572 rs7645759 chr3:10157368 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.08 0.4 1.14e-14 Alzheimer's disease; LIHC cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg06640241 chr16:89574553 SPG7 0.83 15.51 0.64 1.8e-41 Multiple myeloma (IgH translocation); LIHC cis rs7772486 0.790 rs2250387 chr6:146205233 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.5 0.53 4.16e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs965469 1.000 rs6037551 chr20:3306690 T/C cg25506879 chr20:3388711 C20orf194 -0.6 -6.91 -0.35 2.43e-11 IFN-related cytopenia; LIHC cis rs8060686 0.516 rs10852439 chr16:68288331 T/C cg09835421 chr16:68378352 PRMT7 -0.48 -5.91 -0.3 8.43e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs9326248 1.000 rs585849 chr11:117069061 A/G cg15534755 chr11:117069859 TAGLN 0.39 6.62 0.34 1.37e-10 Blood protein levels; LIHC trans rs2077654 0.818 rs4148636 chr11:17427363 A/G cg02039634 chr12:132603558 EP400NL 0.61 6.22 0.32 1.45e-9 Gout; LIHC cis rs6120849 0.707 rs6120826 chr20:33671831 G/A cg24642439 chr20:33292090 TP53INP2 0.65 7.0 0.35 1.35e-11 Protein C levels; LIHC cis rs4665809 1.000 rs6546728 chr2:26276531 G/C cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.28 -0.45 2.03e-18 Gut microbiome composition (summer); LIHC cis rs4718428 0.672 rs36038499 chr7:66289615 A/G cg12165864 chr7:66369176 NA -0.47 -6.81 -0.35 4.31e-11 Corneal structure; LIHC cis rs240764 0.658 rs4840148 chr6:101182500 G/A cg09795085 chr6:101329169 ASCC3 -0.45 -6.59 -0.34 1.66e-10 Neuroticism; LIHC cis rs11764590 0.724 rs1533829 chr7:2082841 A/G cg23422044 chr7:1970798 MAD1L1 -0.48 -7.39 -0.37 1.14e-12 Neuroticism; LIHC trans rs62103177 0.608 rs34383580 chr18:77833263 A/G cg05926928 chr17:57297772 GDPD1 -0.63 -7.03 -0.36 1.1e-11 Opioid sensitivity; LIHC cis rs362296 0.698 rs362282 chr4:3259671 G/A cg06533319 chr4:3265114 C4orf44 0.33 5.79 0.3 1.58e-8 Parental longevity (mother's age at death); LIHC cis rs35110281 0.720 rs162380 chr21:44925283 T/C cg21573476 chr21:45109991 RRP1B 0.54 9.63 0.46 1.44e-19 Mean corpuscular volume; LIHC cis rs35110281 0.837 rs2838341 chr21:45076443 A/G cg21573476 chr21:45109991 RRP1B -0.49 -9.48 -0.46 4.54e-19 Mean corpuscular volume; LIHC cis rs2806561 0.929 rs641452 chr1:23538386 A/G cg19743168 chr1:23544995 NA 0.42 7.94 0.39 2.85e-14 Height; LIHC cis rs6430585 0.528 rs721765 chr2:136748779 C/A cg07305463 chr2:136567211 LCT -0.38 -5.84 -0.3 1.2e-8 Corneal structure; LIHC cis rs611744 0.529 rs13282825 chr8:109263237 T/C cg18478394 chr8:109455254 TTC35 0.42 7.24 0.36 2.98e-12 Dupuytren's disease; LIHC cis rs2439831 0.850 rs68079546 chr15:44136957 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.7 0.34 8.58e-11 Lung cancer in ever smokers; LIHC cis rs12971120 0.891 rs3794953 chr18:72180519 C/T cg26446133 chr18:72167187 CNDP2 -0.78 -14.06 -0.61 9.68e-36 Refractive error; LIHC cis rs10540 1.000 rs35231079 chr11:515224 G/A cg03576123 chr11:487126 PTDSS2 -1.03 -7.25 -0.36 2.89e-12 Body mass index; LIHC cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg10096929 chr1:156261403 TMEM79 -0.38 -6.32 -0.32 8.11e-10 Tonsillectomy; LIHC cis rs2991971 0.782 rs10789463 chr1:45927848 C/A cg15605315 chr1:45957053 TESK2 -0.49 -7.0 -0.35 1.39e-11 High light scatter reticulocyte count; LIHC cis rs17106184 1.000 rs72898923 chr1:50931683 C/T cg07174182 chr1:51127561 FAF1 -0.6 -6.79 -0.34 5.04e-11 Type 2 diabetes; LIHC cis rs6951245 0.580 rs10257426 chr7:1213694 G/A cg22907277 chr7:1156413 C7orf50 0.54 6.21 0.32 1.5e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs832187 0.679 rs9879045 chr3:64001925 C/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.51 -6.83 -0.35 3.78e-11 Schizophrenia; LIHC cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg25894440 chr7:65020034 NA 0.53 6.15 0.32 2.19e-9 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22136351 chr5:94982375 RFESD 0.5 7.24 0.36 2.99e-12 Lung function (FEV1/FVC); LIHC cis rs7223966 0.618 rs9906903 chr17:61634508 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 6.32 0.32 8.38e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs763121 0.853 rs5757166 chr22:38995385 G/T cg14440974 chr22:39074834 NA -0.36 -5.97 -0.31 5.9e-9 Menopause (age at onset); LIHC cis rs1062177 1.000 rs72802204 chr5:151183183 T/C cg00977110 chr5:151150581 G3BP1 0.55 7.06 0.36 9.23e-12 Preschool internalizing problems; LIHC cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg21448741 chr8:58168803 NA 0.37 6.61 0.34 1.46e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg20607798 chr8:58055168 NA 0.64 7.99 0.4 2.15e-14 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.550 rs62183785 chr2:172866976 G/A cg13550731 chr2:172543902 DYNC1I2 0.44 6.83 0.35 4.01e-11 Schizophrenia; LIHC cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg21644426 chr2:191273491 MFSD6 -0.53 -7.34 -0.37 1.56e-12 Pulse pressure; LIHC cis rs8180040 0.967 rs4858890 chr3:47405456 A/G cg16586182 chr3:47516702 SCAP 0.59 10.65 0.5 4.46e-23 Colorectal cancer; LIHC cis rs12464559 0.579 rs6740508 chr2:152613212 T/A cg01189475 chr2:152685088 ARL5A 0.63 7.48 0.38 6.14e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs2928148 0.522 rs11858278 chr15:41416276 T/C cg18705301 chr15:41695430 NDUFAF1 -0.71 -7.57 -0.38 3.62e-13 Glomerular filtration rate in non diabetics (creatinine); LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg10755058 chr3:40428713 ENTPD3 0.43 7.18 0.36 4.36e-12 Renal cell carcinoma; LIHC cis rs6963495 0.818 rs73192141 chr7:105201129 T/G cg19920283 chr7:105172520 RINT1 0.65 5.96 0.31 6.19e-9 Bipolar disorder (body mass index interaction); LIHC cis rs4834770 0.792 rs6823331 chr4:120180790 T/C cg09307838 chr4:120376055 NA 0.41 5.87 0.3 1.05e-8 Blood protein levels; LIHC cis rs7188697 0.922 rs28479997 chr16:58614877 G/A cg02549819 chr16:58548995 SETD6 0.49 7.64 0.38 2.27e-13 QT interval; LIHC cis rs17539620 0.534 rs11541339 chr6:154831643 G/C cg20019720 chr6:154832845 CNKSR3 0.47 7.11 0.36 6.88e-12 Lipoprotein (a) levels; LIHC cis rs875971 0.895 rs12698520 chr7:65918707 C/A cg11764359 chr7:65958608 NA 0.88 15.91 0.65 4.93e-43 Aortic root size; LIHC cis rs2760061 0.603 rs697762 chr1:228192410 G/A cg01200585 chr1:228362443 C1orf69 0.47 7.11 0.36 6.64e-12 Diastolic blood pressure; LIHC cis rs9326248 0.911 rs11216284 chr11:117003060 C/T cg01368799 chr11:117014884 PAFAH1B2 0.43 6.1 0.31 2.83e-9 Blood protein levels; LIHC cis rs611744 0.967 rs682007 chr8:109210326 G/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs11229555 0.574 rs72919749 chr11:58323467 T/C cg15696309 chr11:58395628 NA -0.63 -5.96 -0.31 6.41e-9 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs600806 0.850 rs10858086 chr1:109915075 C/A cg23091122 chr1:110024289 SYPL2 -0.45 -5.94 -0.31 7.16e-9 Intelligence (multi-trait analysis); LIHC cis rs262150 0.659 rs2657340 chr7:158796968 C/T cg19418458 chr7:158789849 NA 0.33 6.08 0.31 3.28e-9 Facial morphology (factor 20); LIHC cis rs1144333 1.000 rs1340684 chr1:76471146 T/C cg10523679 chr1:76189770 ACADM 0.44 6.1 0.31 2.86e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs875971 1.000 rs4718357 chr7:65960878 A/G cg11764359 chr7:65958608 NA 0.91 16.89 0.67 5.59e-47 Aortic root size; LIHC cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.85 -11.08 -0.51 1.35e-24 Alzheimer's disease; LIHC cis rs9948 0.655 rs6758151 chr2:97388884 A/G cg01990225 chr2:97406019 LMAN2L -0.77 -6.44 -0.33 4.06e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs2932538 0.961 rs2932539 chr1:113215786 A/G cg22162597 chr1:113214053 CAPZA1 -0.73 -11.11 -0.52 1.06e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs8180040 0.627 rs9821119 chr3:47198437 C/G cg16586182 chr3:47516702 SCAP -0.48 -8.46 -0.42 7.82e-16 Colorectal cancer; LIHC trans rs17685 0.712 rs60232511 chr7:75800082 A/G cg19862616 chr7:65841803 NCRNA00174 0.94 19.24 0.72 2.06e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17685 0.672 rs1639618 chr7:75701987 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1005277 0.579 rs2474586 chr10:38418882 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.25 -0.52 3.46e-25 Extrinsic epigenetic age acceleration; LIHC cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.93 -10.97 -0.51 3.43e-24 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13115616 chr1:17338059 ATP13A2 0.39 6.12 0.31 2.61e-9 Pancreatic cancer; LIHC trans rs11098499 0.554 rs2175381 chr4:120265967 T/C cg25214090 chr10:38739885 LOC399744 0.44 7.14 0.36 5.6e-12 Corneal astigmatism; LIHC cis rs12922040 1.000 rs12922040 chr16:15869466 C/T cg08214245 chr16:15829296 MYH11 -0.29 -5.86 -0.3 1.08e-8 Serum uric acid levels in response to allopurinol in gout; LIHC cis rs8017423 0.935 rs7144070 chr14:90753047 T/C cg04374321 chr14:90722782 PSMC1 0.76 14.39 0.61 4.79e-37 Mortality in heart failure; LIHC cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg09323728 chr8:95962352 TP53INP1 -0.29 -6.34 -0.32 7.21e-10 Type 2 diabetes; LIHC cis rs7208859 0.623 rs75136574 chr17:28934549 C/A cg14067834 chr17:29058358 SUZ12P 0.66 6.45 0.33 3.75e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7534824 0.625 rs61782085 chr1:101518270 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.75 6.95 0.35 1.89e-11 Refractive astigmatism; LIHC cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg00149659 chr3:10157352 C3orf10 0.7 7.38 0.37 1.23e-12 Alzheimer's disease; LIHC cis rs11864453 0.826 rs12708928 chr16:72137227 C/A cg16558253 chr16:72132732 DHX38 -0.48 -7.37 -0.37 1.29e-12 Fibrinogen levels; LIHC cis rs17433710 0.543 rs4657227 chr1:162653333 A/T cg01063088 chr1:162760584 HSD17B7 0.44 6.09 0.31 3.07e-9 Dupuytren's disease; LIHC cis rs7772486 0.790 rs2265474 chr6:146182092 G/A cg13319975 chr6:146136371 FBXO30 -0.4 -6.53 -0.33 2.34e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs61776719 0.738 rs7555461 chr1:38444749 T/C cg12658694 chr1:38397304 INPP5B -0.57 -8.64 -0.42 2.19e-16 Coronary artery disease; LIHC cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg18357526 chr6:26021779 HIST1H4A 0.93 13.34 0.58 5.81e-33 Intelligence (multi-trait analysis); LIHC cis rs17095355 1.000 rs11194940 chr10:111742223 G/A cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.85 -0.3 1.18e-8 Biliary atresia; LIHC cis rs11958404 0.932 rs72816598 chr5:157436017 G/A cg05962755 chr5:157440814 NA 1.0 11.6 0.53 1.82e-26 IgG glycosylation; LIHC trans rs3743102 0.591 rs8040152 chr15:83356728 C/T cg01542190 chr22:50604728 NA -0.55 -7.44 -0.37 7.96e-13 Colorectal adenoma (advanced); LIHC cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg06481639 chr22:41940642 POLR3H -0.69 -7.07 -0.36 8.6e-12 Vitiligo; LIHC cis rs507080 0.771 rs687664 chr11:118574185 C/A cg04173919 chr11:118528438 PHLDB1 0.32 6.02 0.31 4.44e-9 Serum metabolite levels; LIHC cis rs10883723 0.810 rs6584508 chr10:104258567 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg11890956 chr21:40555474 PSMG1 1.06 15.28 0.64 1.54e-40 Cognitive function; LIHC cis rs7618915 1.000 rs3852064 chr3:52349412 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.35 5.72 0.3 2.33e-8 Bipolar disorder; LIHC cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12971120 0.783 rs7229256 chr18:72169129 T/A cg25817165 chr18:72167213 CNDP2 -0.68 -12.72 -0.57 1.24e-30 Refractive error; LIHC cis rs2073300 0.609 rs6137939 chr20:23390206 C/T cg12062639 chr20:23401060 NAPB -1.06 -14.43 -0.62 3.39e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6952808 0.595 rs3778984 chr7:2166514 T/C cg20295408 chr7:1910781 MAD1L1 -0.41 -5.98 -0.31 5.67e-9 Bipolar disorder and schizophrenia; LIHC cis rs11098499 0.909 rs1809406 chr4:120377122 G/A cg09307838 chr4:120376055 NA 0.79 12.54 0.56 5.98e-30 Corneal astigmatism; LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg06558623 chr16:89946397 TCF25 1.01 15.54 0.64 1.41e-41 Skin colour saturation; LIHC cis rs7208859 0.673 rs11653955 chr17:29033292 C/A cg14067834 chr17:29058358 SUZ12P 0.71 6.92 0.35 2.24e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs208520 0.690 rs866452 chr6:66849936 A/T cg07460842 chr6:66804631 NA -0.76 -8.31 -0.41 2.22e-15 Exhaled nitric oxide output; LIHC cis rs9611565 0.546 rs739134 chr22:42089623 T/C cg06634786 chr22:41940651 POLR3H 0.61 6.74 0.34 6.88e-11 Vitiligo; LIHC cis rs918629 0.798 rs3777168 chr5:95285771 G/A cg10483112 chr5:95245456 ELL2 -0.37 -6.22 -0.32 1.42e-9 IgG glycosylation; LIHC cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.47e-18 Bipolar disorder; LIHC cis rs28735056 0.935 rs72980082 chr18:77630170 G/T cg20368463 chr18:77673604 PQLC1 -0.39 -6.91 -0.35 2.31e-11 Schizophrenia; LIHC cis rs2067615 0.524 rs7309351 chr12:107077432 C/T cg15890332 chr12:107067104 RFX4 -0.27 -6.42 -0.33 4.68e-10 Heart rate; LIHC cis rs8077889 0.645 rs1230393 chr17:41842592 A/G cg26893861 chr17:41843967 DUSP3 -1.14 -21.79 -0.76 1.28e-66 Triglycerides; LIHC cis rs2976388 0.609 rs2717605 chr8:143801015 T/G cg06565975 chr8:143823917 SLURP1 0.33 6.17 0.32 1.93e-9 Urinary tract infection frequency; LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.11 0.4 9.21e-15 Height; LIHC trans rs35110281 0.782 rs9981291 chr21:45031458 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.21e-9 Mean corpuscular volume; LIHC cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg18876405 chr7:65276391 NA 0.54 8.91 0.43 3.17e-17 Aortic root size; LIHC cis rs12701220 0.895 rs10262866 chr7:1019536 G/A cg00990874 chr7:1149470 C7orf50 -0.5 -7.24 -0.36 2.91e-12 Bronchopulmonary dysplasia; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg16132339 chr22:24313637 DDTL;DDT 0.76 14.6 0.62 7.44e-38 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs7618501 0.902 rs7645061 chr3:49868842 C/T cg21659725 chr3:3221576 CRBN 0.97 19.09 0.72 8.38e-56 Intelligence (multi-trait analysis); LIHC trans rs17685 0.753 rs11764129 chr7:75761890 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7520050 0.902 rs1355642 chr1:46598903 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.42 6.16 0.32 1.99e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7572733 0.534 rs734037 chr2:198749269 G/A cg03934865 chr2:198174659 NA 0.45 6.49 0.33 2.96e-10 Dermatomyositis; LIHC trans rs4698048 0.506 rs2080072 chr4:10235622 G/C cg06175025 chr14:78082992 SPTLC2 0.45 6.62 0.34 1.38e-10 Skin aging (microtopography measurement); LIHC cis rs13108904 0.901 rs13119532 chr4:1304505 G/C cg13395646 chr4:1353034 KIAA1530 -0.66 -9.39 -0.45 8.59e-19 Obesity-related traits; LIHC cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9549367 0.789 rs3764125 chr13:113897648 A/G cg18105134 chr13:113819100 PROZ 0.66 11.01 0.51 2.37e-24 Platelet distribution width; LIHC cis rs950169 0.580 rs35516100 chr15:85195430 C/T cg12863693 chr15:85201151 NMB 0.48 7.01 0.35 1.27e-11 Schizophrenia; LIHC cis rs2777491 1.000 rs7167729 chr15:41721042 G/A cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.29 -0.45 1.85e-18 Ulcerative colitis; LIHC cis rs7184046 0.797 rs13737 chr15:75932129 G/T cg20655648 chr15:75932815 IMP3 0.46 6.56 0.33 1.96e-10 Height; LIHC cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.48 6.33 0.32 7.79e-10 Schizophrenia; LIHC cis rs9911578 1.000 rs9898916 chr17:57048660 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.95e-50 Intelligence (multi-trait analysis); LIHC cis rs2625529 0.761 rs972029 chr15:72172986 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.83 -0.3 1.31e-8 Red blood cell count; LIHC cis rs17253792 0.822 rs76267907 chr14:56066969 C/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs2806561 0.796 rs1738467 chr1:23506521 C/T cg12483005 chr1:23474871 LUZP1 0.47 7.5 0.38 5.67e-13 Height; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06438056 chr1:33502433 AK2 -0.49 -6.18 -0.32 1.84e-9 Systolic blood pressure; LIHC cis rs11971779 0.680 rs2355786 chr7:139065622 A/C cg07862535 chr7:139043722 LUC7L2 -0.61 -10.69 -0.5 3.36e-23 Diisocyanate-induced asthma; LIHC cis rs7618915 1.000 rs7618915 chr3:52279594 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.41 6.44 0.33 4.11e-10 Bipolar disorder; LIHC cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.82 0.35 4.07e-11 Gut microbiome composition (summer); LIHC cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg07636037 chr3:49044803 WDR6 -0.74 -12.45 -0.56 1.32e-29 Menarche (age at onset); LIHC cis rs6120849 0.754 rs8501 chr20:33590584 T/C cg24642439 chr20:33292090 TP53INP2 0.66 7.22 0.36 3.49e-12 Protein C levels; LIHC cis rs1003719 0.737 rs2835587 chr21:38461795 A/T cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs6728642 0.908 rs6731522 chr2:97647997 A/G cg26665480 chr2:98280029 ACTR1B -0.63 -5.99 -0.31 5.42e-9 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs1267303 0.642 rs3737740 chr1:47000596 G/A cg25110126 chr1:46999211 NA 0.51 7.15 0.36 5.2e-12 Monobrow; LIHC cis rs4450131 0.522 rs35645049 chr10:126368119 C/G cg20435097 chr10:126320824 FAM53B 0.67 12.23 0.55 8.49e-29 White blood cell count (basophil); LIHC cis rs7927771 0.800 rs12146565 chr11:47398963 G/A cg20135002 chr11:47629003 NA -0.54 -8.99 -0.44 1.71e-17 Subjective well-being; LIHC cis rs2288073 0.965 rs10185445 chr2:24410976 A/C cg06627628 chr2:24431161 ITSN2 0.54 7.53 0.38 4.56e-13 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs11676348 0.818 rs7423433 chr2:218985084 G/A cg00012203 chr2:219082015 ARPC2 -0.55 -7.59 -0.38 3.03e-13 Ulcerative colitis; LIHC cis rs1862618 0.671 rs2591964 chr5:56236900 T/G cg24531977 chr5:56204891 C5orf35 0.53 7.79 0.39 7.8500000000000006e-14 Initial pursuit acceleration; LIHC cis rs597539 0.652 rs654071 chr11:68653432 A/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.96 0.51 3.7e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg07061783 chr6:25882402 NA -0.46 -6.48 -0.33 3.17e-10 Blood metabolite levels; LIHC cis rs17428076 0.793 rs3765166 chr2:172693780 G/A cg13550731 chr2:172543902 DYNC1I2 0.37 6.14 0.32 2.32e-9 Myopia; LIHC cis rs1865760 1.000 rs9358893 chr6:25921761 A/G cg03264133 chr6:25882463 NA -0.38 -5.72 -0.3 2.36e-8 Height; LIHC cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg15382696 chr6:118971807 C6orf204 0.63 6.16 0.32 1.99e-9 Diastolic blood pressure; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg21448741 chr8:58168803 NA 0.36 6.75 0.34 6.49e-11 Developmental language disorder (linguistic errors); LIHC cis rs17376456 0.877 rs10476526 chr5:93461916 G/A cg25358565 chr5:93447407 FAM172A 1.12 10.35 0.49 5.17e-22 Diabetic retinopathy; LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs6752107 0.935 rs10199278 chr2:234160669 C/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.29 0.41 2.57e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.32 -0.52 1.87e-25 Alzheimer's disease; LIHC cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg13395646 chr4:1353034 KIAA1530 0.42 6.54 0.33 2.24e-10 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14295958 chr14:24025576 THTPA 0.53 6.83 0.35 3.81e-11 Lung function (FEV1/FVC); LIHC cis rs28489187 0.706 rs2300637 chr1:85822772 T/C cg16011679 chr1:85725395 C1orf52 0.47 5.86 0.3 1.11e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC trans rs7618501 0.633 rs2856234 chr3:50139142 A/G cg21659725 chr3:3221576 CRBN -0.68 -10.94 -0.51 4.49e-24 Intelligence (multi-trait analysis); LIHC cis rs7534824 0.625 rs7521668 chr1:101491108 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.61 -6.78 -0.34 5.29e-11 Refractive astigmatism; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg19437070 chr15:78442260 IDH3A -0.44 -6.82 -0.35 4.24e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs10489202 1.000 rs12404574 chr1:167961235 C/T cg24449463 chr1:168025552 DCAF6 0.55 7.06 0.36 9.1e-12 Schizophrenia; LIHC cis rs7395581 0.959 rs2013867 chr11:47260272 A/G cg25783544 chr11:47291846 MADD 0.43 6.39 0.33 5.28e-10 HDL cholesterol; LIHC cis rs611744 0.967 rs627019 chr8:109222544 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC trans rs2727020 0.729 rs7924782 chr11:49267249 A/G cg03929089 chr4:120376271 NA -0.81 -14.19 -0.61 3e-36 Coronary artery disease; LIHC cis rs7617773 0.817 rs3731497 chr3:48226553 T/G cg11946769 chr3:48343235 NME6 0.88 10.95 0.51 3.9e-24 Coronary artery disease; LIHC cis rs801193 0.660 rs2659897 chr7:66187715 A/G cg11764359 chr7:65958608 NA -0.82 -14.5 -0.62 1.77e-37 Aortic root size; LIHC cis rs2295359 1.000 rs4655683 chr1:67611613 C/T cg12940439 chr1:67600707 NA 0.4 7.23 0.36 3.28e-12 Psoriasis; LIHC trans rs11039798 0.588 rs7479642 chr11:48553808 G/T cg15704280 chr7:45808275 SEPT13 0.58 6.42 0.33 4.54e-10 Axial length; LIHC cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.53 9.86 0.47 2.3e-20 Total body bone mineral density; LIHC cis rs6831256 0.505 rs11947277 chr4:3473751 C/T cg22890737 chr4:3514540 LRPAP1 0.45 6.35 0.32 7.05e-10 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14676711 chr18:48405181 ME2 -0.48 -6.04 -0.31 3.94e-9 Lung function (FEV1/FVC); LIHC cis rs4654899 0.785 rs9426656 chr1:21505932 T/G cg08539965 chr1:21396338 EIF4G3 0.32 5.74 0.3 2.11e-8 Superior frontal gyrus grey matter volume; LIHC cis rs472402 0.580 rs3736316 chr5:6656210 G/A cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.46 -5.72 -0.3 2.3e-8 Response to amphetamines; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg15586393 chr4:1244086 CTBP1;C4orf42 -0.44 -6.23 -0.32 1.37e-9 Longevity; LIHC cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg11502198 chr6:26597334 ABT1 0.61 9.75 0.47 5.6e-20 Intelligence (multi-trait analysis); LIHC cis rs1113500 0.787 rs473704 chr1:108637310 T/C cg06207961 chr1:108661230 NA -0.31 -5.86 -0.3 1.12e-8 Growth-regulated protein alpha levels; LIHC cis rs9649465 1.000 rs4588795 chr7:123349924 A/G cg03229431 chr7:123269106 ASB15 0.35 7.6 0.38 2.9e-13 Migraine; LIHC cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg21171335 chr12:122356390 WDR66 0.55 7.92 0.39 3.27e-14 Mean corpuscular volume; LIHC cis rs2832191 0.791 rs2832197 chr21:30497790 T/C cg08807101 chr21:30365312 RNF160 -0.57 -8.9 -0.43 3.44e-17 Dental caries; LIHC cis rs7106204 1.000 rs7925633 chr11:24214815 A/G ch.11.24196551F chr11:24239977 NA 0.67 6.75 0.34 6.4e-11 Response to Homoharringtonine (cytotoxicity); LIHC cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC cis rs7917772 0.582 rs4917976 chr10:104360518 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.66 -0.38 1.97e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg03188948 chr7:1209495 NA 0.84 6.21 0.32 1.51e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7903847 0.596 rs869967 chr10:99147975 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7917772 0.503 rs7093285 chr10:104374815 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.68 0.57 1.84e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs67311347 1.000 rs2887995 chr3:40409029 C/G cg13409248 chr3:40428643 ENTPD3 0.4 6.64 0.34 1.2e-10 Renal cell carcinoma; LIHC cis rs1559088 0.546 rs11881543 chr19:33559372 T/G cg27124370 chr19:33622961 WDR88 0.55 7.91 0.39 3.68e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg13607699 chr17:42295918 UBTF 0.62 11.4 0.52 9.78e-26 Total body bone mineral density; LIHC cis rs11583043 1.000 rs6700743 chr1:101447384 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 9.15 0.44 5.43e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs6582630 0.555 rs11182193 chr12:38474090 C/G cg13010199 chr12:38710504 ALG10B 0.43 5.75 0.3 1.99e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg21782813 chr7:2030301 MAD1L1 0.43 7.45 0.37 7.71e-13 Schizophrenia; LIHC cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg18252515 chr7:66147081 NA -1.29 -17.09 -0.68 9.12e-48 Diabetic kidney disease; LIHC cis rs2386661 0.547 rs11259742 chr10:5647078 C/T cg17085576 chr10:5658249 NA -0.34 -6.01 -0.31 4.65e-9 Breast cancer; LIHC cis rs7582180 0.764 rs11683121 chr2:100920705 C/T cg14675211 chr2:100938903 LONRF2 0.52 7.88 0.39 4.47e-14 Intelligence (multi-trait analysis); LIHC cis rs7582180 0.629 rs7597615 chr2:100954828 T/C cg14675211 chr2:100938903 LONRF2 0.54 8.54 0.42 4.39e-16 Intelligence (multi-trait analysis); LIHC cis rs898097 0.578 rs2380173 chr17:80909157 G/T cg15664640 chr17:80829946 TBCD -0.42 -7.03 -0.36 1.1e-11 Breast cancer; LIHC trans rs11165623 0.564 rs12752866 chr1:97000181 T/C cg10631902 chr5:14652156 NA -0.29 -6.81 -0.35 4.31e-11 Hip circumference;Waist circumference; LIHC cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg02931644 chr1:25747376 RHCE 0.35 7.64 0.38 2.2e-13 Erythrocyte sedimentation rate; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.52 0.38 4.75e-13 Prudent dietary pattern; LIHC cis rs6831352 0.918 rs17217949 chr4:100054312 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs12479064 0.604 rs11893359 chr2:99954608 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.6 -7.62 -0.38 2.51e-13 Chronic sinus infection; LIHC cis rs5753037 0.809 rs2074706 chr22:30200893 G/C cg01021169 chr22:30184971 ASCC2 -0.36 -6.79 -0.34 4.94e-11 Type 1 diabetes; LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC trans rs561341 1.000 rs113676348 chr17:30244327 A/G cg20587970 chr11:113659929 NA -0.73 -8.17 -0.4 6.1e-15 Hip circumference adjusted for BMI; LIHC cis rs17685 0.753 rs9691174 chr7:75790405 T/C cg16684958 chr7:75615977 POR 0.52 8.53 0.42 4.68e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7572733 0.515 rs11887138 chr2:198805838 T/A cg00792783 chr2:198669748 PLCL1 0.46 6.86 0.35 3.19e-11 Dermatomyositis; LIHC cis rs11030122 0.702 rs2898947 chr11:3977572 G/A cg18678763 chr11:4115507 RRM1 -0.58 -8.56 -0.42 3.86e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs151997 0.853 rs3846498 chr5:50253625 A/C cg06027927 chr5:50259733 NA -0.62 -8.81 -0.43 6.3e-17 Callous-unemotional behaviour; LIHC cis rs769267 0.965 rs13964 chr19:19468710 C/G cg03709012 chr19:19516395 GATAD2A -0.95 -16.46 -0.66 2.89e-45 Tonsillectomy; LIHC cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg03351412 chr1:154909251 PMVK 0.69 10.0 0.48 7.86e-21 Prostate cancer; LIHC cis rs919433 0.926 rs12618567 chr2:198148191 A/T cg03934865 chr2:198174659 NA -0.61 -9.82 -0.47 3.31e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6424115 0.708 rs11803575 chr1:24182348 A/T cg15997130 chr1:24165203 NA -0.33 -5.95 -0.31 6.79e-9 Immature fraction of reticulocytes; LIHC cis rs7197653 0.748 rs2279538 chr16:68397106 C/G cg09835421 chr16:68378352 PRMT7 -0.82 -9.6 -0.46 1.8e-19 Magnesium levels; LIHC cis rs9311474 0.581 rs13621 chr3:52558133 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.18 0.44 4.33e-18 Electroencephalogram traits; LIHC cis rs7412746 0.658 rs72704652 chr1:150819470 A/G cg17724175 chr1:150552817 MCL1 0.46 8.94 0.44 2.47e-17 Melanoma; LIHC cis rs10751667 0.560 rs10902267 chr11:1007831 T/C cg06064525 chr11:970664 AP2A2 -0.45 -10.81 -0.5 1.28e-23 Alzheimer's disease (late onset); LIHC cis rs11098499 0.863 rs3775848 chr4:120447724 C/T cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC trans rs11689435 0.843 rs16857695 chr2:218344486 G/A cg13544946 chr9:35729779 TLN1 -0.44 -6.35 -0.32 6.82e-10 Metabolite levels (MHPG); LIHC cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg05665937 chr4:1216051 CTBP1 0.44 5.8 0.3 1.47e-8 Obesity-related traits; LIHC cis rs11971779 0.590 rs9642120 chr7:139083971 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs4728302 0.869 rs889826 chr7:133595871 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.54 0.33 2.24e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs2797160 0.651 rs1269176 chr6:126029682 A/T cg05901451 chr6:126070800 HEY2 -0.49 -8.66 -0.42 1.87e-16 Endometrial cancer; LIHC cis rs77669868 0.810 rs686494 chr11:114070160 A/G cg01914181 chr11:114070210 ZBTB16 -0.57 -7.68 -0.38 1.68e-13 Monocyte percentage of white cells; LIHC cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg19318889 chr4:1322082 MAEA 0.46 7.73 0.39 1.24e-13 Obesity-related traits; LIHC cis rs9649465 0.967 rs12538876 chr7:123296320 C/A cg03229431 chr7:123269106 ASB15 -0.39 -8.22 -0.41 4.29e-15 Migraine; LIHC cis rs7927771 0.832 rs4992357 chr11:47393638 C/T cg20135002 chr11:47629003 NA -0.51 -8.7 -0.43 1.45e-16 Subjective well-being; LIHC cis rs7584330 0.554 rs1343768 chr2:238444881 G/A cg08992911 chr2:238395768 MLPH 0.49 5.96 0.31 6.24e-9 Prostate cancer; LIHC cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg17554472 chr22:41940697 POLR3H 0.53 5.88 0.3 9.54e-9 Vitiligo; LIHC trans rs7952251 0.549 rs17114089 chr11:112451038 A/G cg03183631 chr4:26819811 NA -0.3 -6.14 -0.32 2.23e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6879260 0.714 rs888926 chr5:179738101 A/G cg02891314 chr5:179741120 GFPT2 -0.5 -7.0 -0.35 1.36e-11 Height; LIHC cis rs798554 0.757 rs1182181 chr7:2873247 C/G cg13628971 chr7:2884303 GNA12 0.52 7.19 0.36 4.19e-12 Height; LIHC cis rs17685 0.784 rs1613890 chr7:75735037 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.41 -0.37 9.97e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs66887589 0.720 rs2036858 chr4:120249237 A/C cg09307838 chr4:120376055 NA 0.53 8.1 0.4 9.65e-15 Diastolic blood pressure; LIHC cis rs1865760 0.516 rs9379819 chr6:26049819 A/C cg18357526 chr6:26021779 HIST1H4A 0.51 7.46 0.37 7.01e-13 Height; LIHC cis rs9303280 0.901 rs921650 chr17:38069076 G/A cg11212589 chr17:38028394 ZPBP2 -0.34 -6.89 -0.35 2.69e-11 Self-reported allergy; LIHC trans rs1427593 1.000 rs1991411 chr2:137534796 T/C cg04243827 chr5:3103718 NA 0.41 6.07 0.31 3.32e-9 Pancreatic cancer; LIHC cis rs73001065 0.636 rs73002960 chr19:19582992 C/T cg03709012 chr19:19516395 GATAD2A 0.92 9.86 0.47 2.35e-20 LDL cholesterol; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg06873352 chr17:61820015 STRADA 0.6 9.31 0.45 1.59e-18 Height; LIHC cis rs875971 0.862 rs7783779 chr7:65796626 A/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05360265 chr6:147525477 STXBP5 -0.46 -6.22 -0.32 1.44e-9 Pancreatic cancer; LIHC cis rs10193935 1.000 rs13419669 chr2:42387254 T/C cg27598129 chr2:42591480 NA -0.73 -11.36 -0.52 1.41e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs1552244 0.832 rs17050674 chr3:10027258 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.71 9.79 0.47 3.95e-20 Alzheimer's disease; LIHC cis rs2380220 0.872 rs2613529 chr6:95945036 C/T cg15832292 chr6:96025679 MANEA -0.6 -6.73 -0.34 7.25e-11 Behavioural disinhibition (generation interaction); LIHC cis rs3761847 0.622 rs4837807 chr9:123792005 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 6.05 0.31 3.77e-9 Rheumatoid arthritis; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg20102877 chr2:27665638 KRTCAP3 -0.43 -6.01 -0.31 4.79e-9 Total body bone mineral density; LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg07725925 chr16:89976287 TCF25 0.45 6.17 0.32 1.93e-9 Skin colour saturation; LIHC cis rs67311347 1.000 rs6599094 chr3:40399593 A/G cg13409248 chr3:40428643 ENTPD3 0.38 6.19 0.32 1.71e-9 Renal cell carcinoma; LIHC trans rs1814175 0.616 rs10839349 chr11:49753748 C/A cg03929089 chr4:120376271 NA -0.86 -16.6 -0.67 8.18e-46 Height; LIHC cis rs8060686 0.545 rs74629553 chr16:68176415 C/A cg09835421 chr16:68378352 PRMT7 -0.54 -6.05 -0.31 3.78e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs894734 0.535 rs10783613 chr12:54321966 G/T cg17410650 chr12:54324560 NA -0.42 -8.2 -0.41 4.86e-15 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs9549328 0.842 rs6577024 chr13:113634091 G/C cg08528486 chr13:113648767 MCF2L -0.39 -6.35 -0.32 6.69e-10 Systolic blood pressure; LIHC trans rs17685 0.725 rs4476928 chr7:75642107 C/A cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.75 -0.71 1.86e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs763121 0.853 rs5750652 chr22:39048316 A/G cg21395723 chr22:39101663 GTPBP1 0.41 7.0 0.35 1.35e-11 Menopause (age at onset); LIHC cis rs875971 0.862 rs4718377 chr7:66049678 C/T cg18876405 chr7:65276391 NA -0.34 -6.29 -0.32 9.45e-10 Aortic root size; LIHC trans rs1814175 0.588 rs10839463 chr11:49971643 A/G cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs11673344 0.618 rs4420645 chr19:37544988 C/T cg27390819 chr19:37464633 NA -0.51 -6.13 -0.31 2.38e-9 Obesity-related traits; LIHC cis rs2839627 0.561 rs2839601 chr21:44317381 A/G cg18192155 chr21:44258298 NA 0.45 6.49 0.33 3.01e-10 Information processing speed; LIHC cis rs1555322 0.530 rs6060341 chr20:33863633 C/T cg07134254 chr20:33865797 NA -0.53 -6.2 -0.32 1.59e-9 Attention deficit hyperactivity disorder; LIHC cis rs6684514 1.000 rs11264462 chr1:156241728 G/A cg16558208 chr1:156270281 VHLL 0.52 9.66 0.46 1.11e-19 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.9 -0.35 2.6e-11 Gut microbiome composition (summer); LIHC cis rs868036 0.681 rs3784718 chr15:68098004 C/T cg24579218 chr15:68104479 NA -0.34 -5.89 -0.3 9.29e-9 Restless legs syndrome; LIHC cis rs62458065 0.513 rs7805536 chr7:32573570 T/C cg06627557 chr7:32535165 LSM5;AVL9 -0.72 -7.06 -0.36 9.4e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs9596863 0.898 rs4573825 chr13:54324876 A/G ch.13.53330881F chr13:54432880 NA 0.42 5.73 0.3 2.19e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs7264396 0.690 rs2425157 chr20:34419083 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -7.34 -0.37 1.54e-12 Total cholesterol levels; LIHC cis rs1008375 0.966 rs4698636 chr4:17632834 T/C cg04450456 chr4:17643702 FAM184B 0.36 6.1 0.31 2.83e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs116095464 0.558 rs10462755 chr5:246748 T/C cg00938859 chr5:1591904 SDHAP3 0.57 7.09 0.36 7.91e-12 Breast cancer; LIHC cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg05665937 chr4:1216051 CTBP1 0.45 6.05 0.31 3.86e-9 Obesity-related traits; LIHC cis rs8180040 1.000 rs807936 chr3:47322496 C/T cg27129171 chr3:47204927 SETD2 0.64 11.01 0.51 2.46e-24 Colorectal cancer; LIHC cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.5 0.33 2.86e-10 Bipolar disorder; LIHC cis rs7412746 0.658 rs3843843 chr1:150918084 C/T cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs826838 1.000 rs1719848 chr12:39085586 A/G cg26384229 chr12:38710491 ALG10B -0.59 -8.96 -0.44 2.07e-17 Heart rate; LIHC cis rs7777484 0.534 rs2258709 chr7:2832365 C/T cg19717773 chr7:2847554 GNA12 0.43 8.47 0.42 7.48e-16 Height; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg18278596 chr14:105915860 MTA1 0.42 6.45 0.33 3.87e-10 Immature fraction of reticulocytes; LIHC trans rs1432089 0.773 rs72700809 chr4:171784801 C/T cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs709400 1.000 rs709400 chr14:104149475 A/G cg26031613 chr14:104095156 KLC1 1.05 13.94 0.6 2.69e-35 Body mass index; LIHC cis rs1005277 0.579 rs1780133 chr10:38499509 T/C cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs1670533 0.932 rs11731289 chr4:1057773 T/G cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08957018 chr22:42487540 NDUFA6 0.47 6.83 0.35 3.85e-11 Pancreatic cancer; LIHC cis rs1633360 1 rs1633360 chr12:58108052 C/T cg18357645 chr12:58087776 OS9 0.5 8.45 0.42 8.27e-16 Rheumatoid arthritis; LIHC cis rs9393777 0.623 rs56296968 chr6:26474571 C/T cg12826209 chr6:26865740 GUSBL1 0.66 7.06 0.36 9.13e-12 Intelligence (multi-trait analysis); LIHC cis rs1775715 0.769 rs2799030 chr10:32172935 G/T cg14930904 chr10:32216787 ARHGAP12 0.36 6.25 0.32 1.21e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs7428 0.502 rs3184781 chr2:85549527 T/C cg24342717 chr2:85555507 TGOLN2 -0.77 -10.74 -0.5 2.31e-23 Ear protrusion; LIHC cis rs523522 0.571 rs11065120 chr12:120875456 C/T cg27279351 chr12:120934652 DYNLL1 0.51 7.81 0.39 7.28e-14 High light scatter reticulocyte count; LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg11494091 chr17:61959527 GH2 0.44 8.14 0.4 7.19e-15 Prudent dietary pattern; LIHC cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg22800045 chr5:56110881 MAP3K1 0.67 8.82 0.43 5.89e-17 Initial pursuit acceleration; LIHC cis rs1215050 0.791 rs1669745 chr4:98842047 G/A cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.63e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4903214 0.848 rs11627178 chr14:74718280 G/C cg11132536 chr14:74711944 VSX2 -0.24 -5.91 -0.3 8.47e-9 Inflammatory bowel disease; LIHC trans rs7618501 1.000 rs7431106 chr3:49808374 G/A cg21659725 chr3:3221576 CRBN 0.99 19.71 0.73 2.65e-58 Intelligence (multi-trait analysis); LIHC cis rs1075232 1.000 rs16956838 chr15:31819695 C/G cg01030201 chr15:31746330 NA -0.75 -6.33 -0.32 7.87e-10 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs1152591 0.543 rs1152594 chr14:64675044 C/T cg21174375 chr14:64681225 SYNE2 -0.36 -5.87 -0.3 1.02e-8 Atrial fibrillation; LIHC cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg12310025 chr6:25882481 NA 0.5 6.2 0.32 1.63e-9 Intelligence (multi-trait analysis); LIHC cis rs10193935 1.000 rs13386385 chr2:42436928 G/T cg27598129 chr2:42591480 NA -0.74 -11.3 -0.52 2.27e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs7914558 1.000 rs12255047 chr10:104760752 G/A cg15744005 chr10:104629667 AS3MT -0.39 -8.75 -0.43 9.87e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs7927592 0.956 rs12277225 chr11:68340967 T/C cg16797656 chr11:68205561 LRP5 0.5 7.9 0.39 3.77e-14 Total body bone mineral density; LIHC cis rs7582720 1.000 rs115953525 chr2:203744445 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1816752 0.870 rs9581025 chr13:24997825 T/C cg02811702 chr13:24901961 NA 0.23 5.76 0.3 1.89e-8 Obesity-related traits; LIHC cis rs35362007 0.530 rs79171925 chr14:96003075 T/C cg02940042 chr14:96000874 GLRX5;SNHG10;SCARNA13 0.8 6.57 0.33 1.93e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs17685 0.753 rs10245584 chr7:75745866 C/T cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10489202 0.632 rs203779 chr1:167877647 T/G cg24449463 chr1:168025552 DCAF6 -0.62 -9.44 -0.45 6.06e-19 Schizophrenia; LIHC cis rs9486719 1.000 rs12208011 chr6:96991105 G/A cg06623918 chr6:96969491 KIAA0776 -0.72 -7.23 -0.36 3.08e-12 Migraine;Coronary artery disease; LIHC cis rs769267 0.965 rs2965198 chr19:19473030 A/G cg15052019 chr19:19431593 KIAA0892;SF4 -0.46 -6.48 -0.33 3.17e-10 Tonsillectomy; LIHC cis rs1664789 1.000 rs1664789 chr5:53282649 C/T ch.5.1024479R chr5:53302184 ARL15 -0.51 -8.2 -0.41 5.03e-15 Waist circumference adjusted for body mass index; LIHC trans rs13113518 0.812 rs11945371 chr4:56275230 G/T cg15358633 chr12:38710606 ALG10B 0.42 6.04 0.31 3.98e-9 Height; LIHC cis rs4819052 0.851 rs7276828 chr21:46695039 T/G cg22633049 chr21:46681294 NA -0.38 -6.51 -0.33 2.64e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7618501 1.000 rs3749241 chr3:49744392 A/G cg21467203 chr3:49911342 NA 0.4 6.77 0.34 5.51e-11 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.686 rs2991986 chr1:46081282 A/G cg06784218 chr1:46089804 CCDC17 -0.41 -7.5 -0.38 5.49e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11718455 0.767 rs6771202 chr3:43990087 A/T cg08738300 chr3:44038990 NA 0.52 8.84 0.43 5.2e-17 Coronary artery disease; LIHC cis rs6964587 1.000 rs10225885 chr7:91671007 A/G cg17063962 chr7:91808500 NA 1.0 19.01 0.72 1.74e-55 Breast cancer; LIHC cis rs2361718 0.500 rs12451697 chr17:78100690 T/A cg09238746 chr17:78121135 EIF4A3 -0.67 -10.36 -0.49 4.55e-22 Yeast infection; LIHC cis rs6977660 0.943 rs10240816 chr7:19819620 A/C cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs6430585 0.528 rs309162 chr2:136690783 T/A cg07169764 chr2:136633963 MCM6 1.29 21.97 0.77 2.37e-67 Corneal structure; LIHC cis rs9649213 0.593 rs6973775 chr7:98004685 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.95 -0.31 6.69e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs13108904 0.905 rs34490749 chr4:1217981 A/G cg00684032 chr4:1343700 KIAA1530 0.38 5.83 0.3 1.28e-8 Obesity-related traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05291385 chr2:73461228 CCT7;C2orf7 -0.56 -6.55 -0.33 2.13e-10 Systolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05889321 chr10:97416837 ALDH18A1 0.52 8.58 0.42 3.42e-16 Cognitive function; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg09331995 chr7:27309021 NA 0.42 6.84 0.35 3.55e-11 Bilirubin levels; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs6502050 0.765 rs6502074 chr17:80121776 T/C cg11859384 chr17:80120422 CCDC57 -0.42 -5.75 -0.3 2.02e-8 Life satisfaction; LIHC trans rs875971 0.545 rs801212 chr7:66015630 C/G cg26939375 chr7:64535504 NA -0.4 -6.31 -0.32 8.63e-10 Aortic root size; LIHC cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.68 0.46 9.5e-20 Bipolar disorder; LIHC cis rs2637266 1.000 rs1077916 chr10:78381951 G/A cg18941641 chr10:78392320 NA 0.27 5.72 0.3 2.35e-8 Pulmonary function; LIHC cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg02503808 chr4:7069936 GRPEL1 0.79 11.67 0.53 9.87e-27 Monocyte percentage of white cells; LIHC cis rs9457247 0.663 rs1894603 chr6:167434686 C/T cg12798992 chr6:167411361 FGFR1OP -0.45 -7.29 -0.37 2.2e-12 Crohn's disease; LIHC cis rs831571 0.653 rs73120967 chr3:64070372 C/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.52 -5.93 -0.31 7.48e-9 Type 2 diabetes; LIHC cis rs1707322 0.717 rs28396194 chr1:46213227 C/T cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs763121 0.853 rs5757141 chr22:38957483 G/A cg14440974 chr22:39074834 NA -0.44 -6.94 -0.35 1.95e-11 Menopause (age at onset); LIHC cis rs6456156 0.586 rs2345753 chr6:167484344 T/A cg12798992 chr6:167411361 FGFR1OP 0.44 6.65 0.34 1.13e-10 Primary biliary cholangitis; LIHC cis rs6456156 0.692 rs9457270 chr6:167512928 A/G cg07741184 chr6:167504864 NA 0.33 8.03 0.4 1.61e-14 Primary biliary cholangitis; LIHC cis rs7534824 0.625 rs61780328 chr1:101458754 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 7.49 0.38 5.92e-13 Refractive astigmatism; LIHC cis rs7395581 0.918 rs4752824 chr11:47324666 A/T cg26139080 chr11:47293733 MADD -0.51 -8.64 -0.42 2.24e-16 HDL cholesterol; LIHC trans rs2018683 0.768 rs10282015 chr7:29022138 G/A cg19402173 chr7:128379420 CALU -0.4 -6.29 -0.32 9.87e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs763014 1.000 rs2269558 chr16:682250 C/T cg07343612 chr16:622815 PIGQ -0.86 -14.98 -0.63 2.28e-39 Height; LIHC cis rs1865721 0.728 rs8087297 chr18:73136221 T/A cg26385618 chr18:73139727 C18orf62 -0.31 -8.46 -0.42 7.65e-16 Intelligence; LIHC cis rs1707322 1.000 rs4660906 chr1:46470860 C/T cg03146154 chr1:46216737 IPP 0.48 7.78 0.39 8.47e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17376456 0.569 rs10050364 chr5:93064127 T/C cg25358565 chr5:93447407 FAM172A 0.81 7.72 0.39 1.29e-13 Diabetic retinopathy; LIHC trans rs61931739 0.500 rs7311302 chr12:34557211 T/C cg26384229 chr12:38710491 ALG10B 0.63 8.01 0.4 1.76e-14 Morning vs. evening chronotype; LIHC cis rs9457247 1.000 rs430293 chr6:167404958 A/G cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg27309282 chr4:1016081 FGFRL1 0.37 6.15 0.32 2.16e-9 Oropharynx cancer; LIHC trans rs2262909 0.962 rs73019842 chr19:22249909 T/G cg17074339 chr11:11642133 GALNTL4 0.4 6.09 0.31 3.09e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC trans rs7714584 1.000 rs6579803 chr5:150255559 C/T cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs644799 0.544 rs1527450 chr11:95467777 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.53 6.77 0.34 5.58e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs853679 0.517 rs9393885 chr6:28050009 A/T cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs950169 0.580 rs2271431 chr15:85189464 A/C cg12863693 chr15:85201151 NMB 0.49 7.15 0.36 5.22e-12 Schizophrenia; LIHC cis rs4407350 0.868 rs5765719 chr22:44917849 A/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.23 -0.32 1.38e-9 Intelligence (multi-trait analysis); LIHC cis rs425277 0.606 rs262664 chr1:2083537 G/C cg24578937 chr1:2090814 PRKCZ 0.32 5.92 0.3 7.9e-9 Height; LIHC cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg03806693 chr22:41940476 POLR3H -1.07 -12.44 -0.56 1.42e-29 Vitiligo; LIHC cis rs7945718 0.967 rs10765989 chr11:12769397 A/G cg25843174 chr11:12811716 TEAD1 -0.27 -6.28 -0.32 1e-9 Educational attainment (years of education); LIHC cis rs7914558 0.966 rs7908280 chr10:104816947 C/G cg15744005 chr10:104629667 AS3MT -0.39 -8.74 -0.43 1.09e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs6679073 1.000 rs6679073 chr1:205756484 A/C cg23034840 chr1:205782522 SLC41A1 0.43 6.84 0.35 3.62e-11 Prostate-specific antigen levels; LIHC cis rs1552244 0.554 rs3732965 chr3:10048760 A/C cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs4073582 0.595 rs708471 chr11:65931008 A/G cg14036092 chr11:66035641 RAB1B 0.41 6.01 0.31 4.67e-9 Gout; LIHC cis rs79149102 0.579 rs7173218 chr15:75315328 A/G cg17294928 chr15:75287854 SCAMP5 -0.47 -6.12 -0.31 2.57e-9 Lung cancer; LIHC cis rs10744422 1.000 rs10847869 chr12:123328359 C/G cg18912006 chr12:123335444 HIP1R -0.58 -7.11 -0.36 6.8e-12 Schizophrenia; LIHC cis rs6570726 0.791 rs6570692 chr6:145904401 T/A cg23711669 chr6:146136114 FBXO30 0.7 12.05 0.55 4.21e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9393692 0.905 rs1124999 chr6:26287043 G/T cg00631329 chr6:26305371 NA -0.45 -7.56 -0.38 3.85e-13 Educational attainment; LIHC cis rs7715806 0.500 rs34355 chr5:74959970 G/A cg02573091 chr5:74908125 NA -0.51 -6.13 -0.31 2.46e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9790314 0.967 rs339101 chr3:161064193 A/T cg03342759 chr3:160939853 NMD3 -0.66 -7.94 -0.39 2.98e-14 Morning vs. evening chronotype; LIHC cis rs74181299 0.964 rs2723065 chr2:65279414 A/G cg05010058 chr2:65284262 CEP68 0.4 6.78 0.34 5.3e-11 Pulse pressure; LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg06558623 chr16:89946397 TCF25 0.94 14.52 0.62 1.56e-37 Skin colour saturation; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg09367891 chr1:107599246 PRMT6 -0.73 -11.99 -0.54 7e-28 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21843114 chr4:26334859 RBPJ 0.45 6.1 0.31 2.83e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs2727020 0.724 rs4109837 chr11:49372051 A/T cg03929089 chr4:120376271 NA -0.66 -9.86 -0.47 2.31e-20 Coronary artery disease; LIHC cis rs1419980 0.673 rs12366473 chr12:7728270 G/C cg25828445 chr12:7781288 NA 0.44 6.76 0.34 6.04e-11 HDL cholesterol levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24557133 chr1:234509059 C1orf31 -0.56 -6.52 -0.33 2.53e-10 Systolic blood pressure; LIHC cis rs7786877 0.723 rs11764045 chr7:100212754 C/T cg00334542 chr7:100209784 MOSPD3 -0.73 -7.5 -0.38 5.48e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.593 rs7000752 chr8:58026980 C/G cg20607798 chr8:58055168 NA 0.45 6.44 0.33 3.94e-10 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.638 rs7793569 chr7:66116633 T/G cg11764359 chr7:65958608 NA -0.71 -10.58 -0.5 8.16e-23 Aortic root size; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg24157651 chr18:47018588 SNORD58A;SNORD58B;RPL17 -0.5 -6.23 -0.32 1.4e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs714515 0.502 rs4916254 chr1:172364012 G/A cg01573306 chr1:172330400 DNM3 0.39 5.73 0.3 2.26e-8 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs2204008 0.543 rs2387018 chr12:38065638 C/T cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.5e-21 Bladder cancer; LIHC cis rs9814567 0.686 rs1404289 chr3:134358109 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.52 8.34 0.41 1.89e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7223966 1.000 rs16947014 chr17:61719032 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.65 0.34 1.15e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2948294 0.588 rs12544596 chr8:8116346 A/T cg06636001 chr8:8085503 FLJ10661 0.4 6.36 0.33 6.47e-10 Red cell distribution width; LIHC cis rs9611565 0.592 rs56021266 chr22:41756571 C/T cg06634786 chr22:41940651 POLR3H -0.77 -7.43 -0.37 8.94e-13 Vitiligo; LIHC cis rs12220238 1.000 rs10824084 chr10:75911415 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.77 0.34 5.63e-11 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs820218 0.847 rs820190 chr17:73625286 G/A cg14452952 chr6:108548360 SNX3 0.38 6.03 0.31 4.16e-9 Rotator cuff tears; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11625262 chr3:156393772 TIPARP;LOC100287227 -0.44 -6.23 -0.32 1.4e-9 Longevity; LIHC cis rs3793683 1.000 rs3793683 chr10:134568387 G/T cg27297192 chr10:134578999 INPP5A -0.51 -7.9 -0.39 3.8e-14 Migraine; LIHC cis rs3892630 0.757 rs8109823 chr19:33183316 A/G cg22980127 chr19:33182716 NUDT19 1.05 12.58 0.56 4.2000000000000004e-30 Red blood cell traits; LIHC cis rs2832191 0.655 rs2247110 chr21:30323888 G/A cg08807101 chr21:30365312 RNF160 -0.79 -11.71 -0.54 7.28e-27 Dental caries; LIHC cis rs7116495 0.609 rs2276396 chr11:71823905 G/C cg10381502 chr11:71823885 C11orf51 1.05 8.87 0.43 4.11e-17 Severe influenza A (H1N1) infection; LIHC cis rs668210 0.947 rs559161 chr11:65761637 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.52 6.72 0.34 7.53e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs796364 0.806 rs55985986 chr2:201120987 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.8 -8.83 -0.43 5.64e-17 Schizophrenia; LIHC cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.95 0.31 6.58e-9 Aortic root size; LIHC cis rs60871478 0.898 rs4720929 chr7:808009 T/C cg27478167 chr7:817139 HEATR2 -0.41 -5.82 -0.3 1.38e-8 Cerebrospinal P-tau181p levels; LIHC cis rs10791097 0.694 rs6590520 chr11:130747386 C/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.18e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg13047869 chr3:10149882 C3orf24 0.54 6.45 0.33 3.89e-10 Alzheimer's disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20658100 chr13:74707145 KLF12 0.36 6.28 0.32 1.03e-9 Calcium levels; LIHC cis rs9790314 0.723 rs10936223 chr3:160884313 C/A cg03342759 chr3:160939853 NMD3 -0.76 -12.29 -0.55 5.43e-29 Morning vs. evening chronotype; LIHC trans rs17685 0.753 rs55812043 chr7:75747241 T/C cg19862616 chr7:65841803 NCRNA00174 0.91 18.75 0.71 1.96e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg18252515 chr7:66147081 NA 1.28 17.42 0.69 4.2e-49 Diabetic kidney disease; LIHC cis rs6570726 0.846 rs4896824 chr6:145927048 C/T cg23711669 chr6:146136114 FBXO30 0.61 10.5 0.49 1.6e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2336384 1.000 rs1810563 chr1:12054030 A/G cg13216073 chr1:12042593 MFN2 -0.45 -6.52 -0.33 2.49e-10 Platelet count; LIHC trans rs1814175 0.588 rs34449937 chr11:49756013 G/A cg03929089 chr4:120376271 NA -0.85 -16.54 -0.67 1.44e-45 Height; LIHC cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg20887711 chr4:1340912 KIAA1530 0.48 7.36 0.37 1.42e-12 Obesity-related traits; LIHC cis rs62079673 0.527 rs9788998 chr17:80605644 A/G cg13639189 chr17:80606880 WDR45L 0.67 11.21 0.52 4.76e-25 Breast cancer; LIHC trans rs2243480 1.000 rs4145008 chr7:65647511 T/G cg10756647 chr7:56101905 PSPH -1.07 -13.17 -0.58 2.44e-32 Diabetic kidney disease; LIHC cis rs798554 0.796 rs2158694 chr7:2863443 T/G cg19717773 chr7:2847554 GNA12 -0.44 -7.0 -0.35 1.32e-11 Height; LIHC cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.63 0.53 1.49e-26 Alzheimer's disease; LIHC cis rs10751667 0.643 rs6597969 chr11:928843 C/T cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC cis rs798554 0.797 rs798493 chr7:2798731 A/G cg13628971 chr7:2884303 GNA12 0.54 7.9 0.39 3.9e-14 Height; LIHC cis rs1577917 0.570 rs114854865 chr6:86554236 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.16 -0.4 6.39e-15 Response to antipsychotic treatment; LIHC cis rs10927875 0.632 rs4661667 chr1:16162731 C/T cg21385522 chr1:16154831 NA -1.04 -17.41 -0.69 4.75e-49 Dilated cardiomyopathy; LIHC cis rs918629 0.798 rs10052503 chr5:95283658 A/C cg10483112 chr5:95245456 ELL2 -0.36 -6.3 -0.32 9.17e-10 IgG glycosylation; LIHC cis rs2153535 0.580 rs5001322 chr6:8451608 A/G cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC cis rs12908161 1.000 rs17600551 chr15:85319258 A/G cg12863693 chr15:85201151 NMB 0.44 6.33 0.32 7.52e-10 Schizophrenia; LIHC cis rs798554 1.000 rs798554 chr7:2759795 C/T cg13628971 chr7:2884303 GNA12 0.5 7.23 0.36 3.12e-12 Height; LIHC cis rs11971779 0.616 rs6467836 chr7:139023517 C/G cg07862535 chr7:139043722 LUC7L2 0.59 10.08 0.48 4.39e-21 Diisocyanate-induced asthma; LIHC cis rs5769707 0.681 rs4824068 chr22:50024801 G/A cg07959070 chr22:50026188 C22orf34 -0.34 -8.39 -0.41 1.27e-15 Monocyte count;Monocyte percentage of white cells; LIHC trans rs1450439 0.948 rs7698039 chr4:139495535 G/T cg27294979 chr16:69786225 NOB1 0.44 6.41 0.33 4.72e-10 Lung function (forced expiratory volume in 1 second); LIHC cis rs780094 0.544 rs2303370 chr2:27651375 C/T cg27432699 chr2:27873401 GPN1 -0.44 -6.12 -0.31 2.57e-9 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs832187 0.704 rs832195 chr3:63864612 T/C cg16258503 chr3:63850278 ATXN7;THOC7 0.5 7.08 0.36 8.1e-12 Schizophrenia; LIHC cis rs12286929 0.933 rs11215381 chr11:115022233 T/C cg04055981 chr11:115044050 NA 0.42 6.84 0.35 3.57e-11 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs5769765 0.954 rs6009900 chr22:50236610 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -8.83 -0.43 5.66e-17 Schizophrenia; LIHC cis rs5753037 0.809 rs140150 chr22:30185719 C/G cg01021169 chr22:30184971 ASCC2 -0.36 -6.84 -0.35 3.71e-11 Type 1 diabetes; LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg07677032 chr17:61819896 STRADA -0.4 -5.8 -0.3 1.52e-8 Prudent dietary pattern; LIHC cis rs17826219 0.636 rs7221463 chr17:29080551 A/C cg13385521 chr17:29058706 SUZ12P 0.8 7.83 0.39 6.35e-14 Body mass index; LIHC cis rs2292864 1.000 rs2292864 chr17:45367681 C/T cg18085866 chr17:45331354 ITGB3 -0.52 -5.88 -0.3 9.96e-9 Left atrial antero-posterior diameter; LIHC cis rs1577917 0.771 rs2484355 chr6:86394403 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -12.69 -0.57 1.66e-30 Response to antipsychotic treatment; LIHC cis rs2549003 1.000 rs2549002 chr5:131829578 C/A cg21138405 chr5:131827807 IRF1 -0.39 -10.52 -0.49 1.26e-22 Asthma (sex interaction); LIHC cis rs10508774 1.000 rs72795557 chr10:32870507 C/G cg01819863 chr10:32635814 EPC1 0.65 6.01 0.31 4.73e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8141529 0.664 rs5762862 chr22:29252732 C/T cg15103426 chr22:29168792 CCDC117 0.51 7.95 0.39 2.8e-14 Lymphocyte counts; LIHC trans rs11098499 0.865 rs11098513 chr4:120316075 A/G cg25214090 chr10:38739885 LOC399744 0.57 9.12 0.44 6.65e-18 Corneal astigmatism; LIHC cis rs8072548 1 rs8072548 chr17:38164025 T/G cg17467752 chr17:38218738 THRA 0.64 11.78 0.54 4.19e-27 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg02782426 chr3:40428986 ENTPD3 -0.34 -6.3 -0.32 9.3e-10 Renal cell carcinoma; LIHC cis rs12472274 0.648 rs67102443 chr2:239084602 A/G cg17459225 chr2:239074497 NA 0.63 10.35 0.49 5.25e-22 Phospholipid levels (plasma); LIHC cis rs3736485 0.934 rs4143724 chr15:51870413 T/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1.05e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12477438 0.765 rs6750876 chr2:99679673 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs1577917 1.000 rs955197 chr6:86729675 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.16 -0.48 2.35e-21 Response to antipsychotic treatment; LIHC cis rs71017072 1 rs71017072 chr7:19794295 G/GA cg07541023 chr7:19748670 TWISTNB 0.39 5.97 0.31 5.81e-9 Rubella; LIHC cis rs17094222 0.797 rs1541264 chr10:102433682 C/T cg26540559 chr10:102447443 NA 0.31 6.08 0.31 3.16e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1814175 0.791 rs11040513 chr11:49778153 G/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.51 -0.79 2.04e-73 Height; LIHC cis rs11628318 0.614 rs1190342 chr14:103100382 C/T cg12046867 chr14:103022105 NA -0.47 -6.79 -0.34 4.94e-11 Platelet count; LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg10780191 chr14:69261284 ZFP36L1 -0.77 -6.48 -0.33 3.21e-10 Mild influenza (H1N1) infection; LIHC cis rs1865760 0.534 rs72834629 chr6:26023032 C/T cg17691542 chr6:26056736 HIST1H1C 0.6 7.88 0.39 4.32e-14 Height; LIHC cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg20684491 chr1:25596433 NA -0.29 -6.04 -0.31 3.97e-9 Erythrocyte sedimentation rate; LIHC cis rs796364 1.000 rs281785 chr2:200749566 A/G cg23649088 chr2:200775458 C2orf69 0.5 5.88 0.3 9.95e-9 Schizophrenia; LIHC cis rs74181299 0.712 rs2241161 chr2:65290842 A/C cg05010058 chr2:65284262 CEP68 -0.36 -6.31 -0.32 8.66e-10 Pulse pressure; LIHC cis rs6545883 0.811 rs778753 chr2:61780200 T/A cg14146966 chr2:61757674 XPO1 0.32 5.72 0.3 2.34e-8 Tuberculosis; LIHC cis rs892961 0.899 rs72896163 chr17:75412525 C/T cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs2204008 0.652 rs11513964 chr12:37998214 C/G cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs9790314 1.000 rs1600209 chr3:161038217 A/T cg04691961 chr3:161091175 C3orf57 -0.42 -6.53 -0.33 2.34e-10 Morning vs. evening chronotype; LIHC cis rs13118159 0.801 rs7690727 chr4:1340811 C/A cg16405210 chr4:1374714 KIAA1530 -0.57 -7.12 -0.36 6.48e-12 Longevity; LIHC cis rs10871290 0.650 rs28484753 chr16:74489395 G/C cg01733217 chr16:74700730 RFWD3 0.44 7.82 0.39 6.76e-14 Breast cancer; LIHC cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg16497277 chr3:49208875 KLHDC8B -0.5 -6.34 -0.32 7.07e-10 Menarche (age at onset); LIHC cis rs2228479 0.850 rs17232630 chr16:89851179 C/T cg19635926 chr16:89946313 TCF25 0.51 6.41 0.33 4.89e-10 Skin colour saturation; LIHC cis rs8062405 0.755 rs2077031 chr16:28603168 T/A cg07382826 chr16:28625726 SULT1A1 0.51 7.92 0.39 3.41e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6598163 0.712 rs10751695 chr12:132291061 A/C cg07389463 chr12:132296394 NA 0.24 6.03 0.31 4.25e-9 Migraine; LIHC cis rs9291683 0.595 rs35501905 chr4:10053431 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.44 0.37 8.39e-13 Bone mineral density; LIHC cis rs12477438 0.798 rs6736064 chr2:99658201 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.85 -0.65 8.31e-43 Chronic sinus infection; LIHC cis rs8067354 0.645 rs2132715 chr17:57858374 A/T cg02344993 chr17:57696989 CLTC 0.7 11.66 0.53 1.16e-26 Hemoglobin concentration; LIHC cis rs12477438 0.520 rs11123766 chr2:99780915 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.2 0.61 2.65e-36 Chronic sinus infection; LIHC cis rs6840360 0.967 rs10049728 chr4:152672121 C/G cg22705602 chr4:152727874 NA -0.34 -7.15 -0.36 5.15e-12 Intelligence (multi-trait analysis); LIHC cis rs4820539 1.000 rs4822358 chr22:23474795 A/G cg14186256 chr22:23484241 RTDR1 0.98 21.51 0.76 1.58e-65 Bone mineral density; LIHC cis rs11676348 0.818 rs6436031 chr2:218979259 T/C cg00012203 chr2:219082015 ARPC2 -0.55 -7.57 -0.38 3.54e-13 Ulcerative colitis; LIHC cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs929354 0.772 rs3802118 chr7:156986814 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.92 0.3 7.91e-9 Body mass index; LIHC cis rs116095464 0.558 rs6875291 chr5:264192 T/C cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg18404041 chr3:52824283 ITIH1 -0.59 -9.32 -0.45 1.44e-18 Bipolar disorder; LIHC cis rs11031096 0.754 rs4910886 chr11:4143721 G/T cg18678763 chr11:4115507 RRM1 -0.52 -8.04 -0.4 1.47e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs10506458 0.915 rs12423078 chr12:63397529 C/T cg22491629 chr6:157744540 C6orf35 -0.62 -11.1 -0.51 1.2e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs1986734 0.555 rs12512288 chr4:77416817 C/G cg24201034 chr4:77507246 SHROOM3 -0.37 -5.93 -0.31 7.46e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg06634786 chr22:41940651 POLR3H 0.68 7.27 0.37 2.43e-12 Vitiligo; LIHC cis rs9649213 0.593 rs7781916 chr7:97929738 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.82e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs796364 1.000 rs281794 chr2:200846666 C/T cg23649088 chr2:200775458 C2orf69 0.49 5.97 0.31 5.81e-9 Schizophrenia; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg00106254 chr7:1943704 MAD1L1 -0.47 -7.86 -0.39 5.22e-14 Autism spectrum disorder or schizophrenia; LIHC cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs3096299 0.933 rs2965823 chr16:89454924 G/A cg01788221 chr16:89496183 ANKRD11 -0.38 -6.0 -0.31 5.1e-9 Multiple myeloma (IgH translocation); LIHC cis rs9611565 0.559 rs132771 chr22:42025350 A/G cg06634786 chr22:41940651 POLR3H 0.71 7.38 0.37 1.23e-12 Vitiligo; LIHC cis rs10425738 0.536 rs10426903 chr19:41417719 T/C cg14550611 chr19:41354682 CYP2A6 0.36 5.78 0.3 1.64e-8 nicotine metabolite ratio in current smokers;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); LIHC cis rs11628318 0.614 rs3825565 chr14:103060465 G/A cg12046867 chr14:103022105 NA -0.48 -6.94 -0.35 1.94e-11 Platelet count; LIHC cis rs7589728 0.925 rs78829281 chr2:88502293 T/A cg14558114 chr2:88469736 THNSL2 0.6 5.72 0.3 2.35e-8 Plasma clusterin levels; LIHC cis rs72781680 0.898 rs12623333 chr2:24111823 T/G cg08917208 chr2:24149416 ATAD2B 0.87 8.2 0.41 4.78e-15 Lymphocyte counts; LIHC cis rs12497850 1.000 rs6788650 chr3:48749543 T/C cg07636037 chr3:49044803 WDR6 0.8 13.8 0.6 9.38e-35 Parkinson's disease; LIHC cis rs6429082 0.668 rs291395 chr1:235652049 A/C cg26050004 chr1:235667680 B3GALNT2 -0.76 -12.32 -0.55 4.07e-29 Adiposity; LIHC cis rs12824058 0.831 rs12320318 chr12:130812335 T/C cg26677194 chr12:130822605 PIWIL1 0.51 7.25 0.36 2.88e-12 Menopause (age at onset); LIHC trans rs2073499 0.935 rs74398439 chr3:50331927 C/T cg21659725 chr3:3221576 CRBN 0.6 6.47 0.33 3.42e-10 Schizophrenia; LIHC cis rs12220238 1.000 rs11000936 chr10:75992383 A/T cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.89 0.35 2.69e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7326068 0.524 rs2497488 chr13:21201476 A/T cg12081946 chr13:21296465 IL17D 0.37 5.98 0.31 5.58e-9 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs4423214 1.000 rs12806844 chr11:71170770 G/A cg05163923 chr11:71159392 DHCR7 0.89 13.62 0.59 4.7e-34 Vitamin D levels; LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg24209194 chr3:40518798 ZNF619 -0.64 -9.72 -0.47 6.96e-20 Renal cell carcinoma; LIHC cis rs4820539 1.000 rs6003518 chr22:23471533 C/T cg14186256 chr22:23484241 RTDR1 0.99 21.59 0.76 7.69e-66 Bone mineral density; LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg11062466 chr8:58055876 NA 0.51 7.6 0.38 2.84e-13 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg00612595 chr21:47717864 NA -0.42 -6.62 -0.34 1.36e-10 Testicular germ cell tumor; LIHC cis rs2239547 0.657 rs6445538 chr3:52874288 T/C cg18404041 chr3:52824283 ITIH1 -0.44 -6.03 -0.31 4.29e-9 Schizophrenia; LIHC cis rs477895 0.713 rs7952318 chr11:63961242 G/A cg04317338 chr11:64019027 PLCB3 0.77 9.4 0.45 8.09e-19 Mean platelet volume; LIHC cis rs2279817 0.818 rs34421778 chr1:17984859 C/G cg21791023 chr1:18019539 ARHGEF10L -0.65 -7.14 -0.36 5.63e-12 Neuroticism; LIHC trans rs11098499 0.789 rs1980024 chr4:120253047 C/T cg25214090 chr10:38739885 LOC399744 0.5 8.13 0.4 7.9e-15 Corneal astigmatism; LIHC cis rs72781680 0.898 rs72782136 chr2:24047344 A/G cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg16103275 chr6:290800 DUSP22 0.53 7.13 0.36 6.01e-12 Menopause (age at onset); LIHC cis rs7301016 0.846 rs17732089 chr12:63023658 A/G cg11441379 chr12:63026424 NA -0.61 -6.22 -0.32 1.45e-9 IgG glycosylation; LIHC cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg16145915 chr7:1198662 ZFAND2A -0.33 -7.88 -0.39 4.34e-14 Longevity;Endometriosis; LIHC cis rs739401 0.572 rs739399 chr11:3016452 A/G cg08508325 chr11:3079039 CARS -0.29 -6.25 -0.32 1.19e-9 Longevity; LIHC cis rs1348850 0.519 rs4144275 chr2:178523368 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 7.96 0.4 2.57e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs11229555 0.645 rs12290089 chr11:58176849 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7959452 0.562 rs10878975 chr12:69782044 G/C cg22834771 chr12:69754056 YEATS4 -0.52 -9.23 -0.45 2.82e-18 Blood protein levels; LIHC cis rs3106136 0.534 rs13109764 chr4:95304506 T/C cg11021082 chr4:95130006 SMARCAD1 0.34 5.85 0.3 1.14e-8 Capecitabine sensitivity; LIHC cis rs7771547 0.573 rs546353 chr6:36398597 C/A cg07856975 chr6:36356162 ETV7 0.36 5.86 0.3 1.08e-8 Platelet distribution width; LIHC cis rs2455799 0.613 rs2470538 chr3:15717124 G/C cg12698662 chr3:15914712 MIR563 -0.4 -7.3 -0.37 2.01e-12 Mean platelet volume; LIHC cis rs4423214 0.921 rs11603330 chr11:71153459 C/A cg24826892 chr11:71159390 DHCR7 0.52 6.69 0.34 9.2e-11 Vitamin D levels; LIHC cis rs738322 1.000 rs133009 chr22:38569653 G/C cg25457927 chr22:38595422 NA -0.26 -6.36 -0.33 6.6e-10 Cutaneous nevi; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15984612 chr8:145514624 BOP1;HSF1 0.46 6.87 0.35 3.07e-11 Cognitive function; LIHC trans rs1814175 0.745 rs7483456 chr11:49774613 C/T cg03929089 chr4:120376271 NA -0.9 -18.39 -0.71 5.32e-53 Height; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg04577441 chr4:100870687 LOC256880;H2AFZ 0.31 6.13 0.31 2.47e-9 Immature fraction of reticulocytes; LIHC cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg11645453 chr3:52864694 ITIH4 0.21 5.83 0.3 1.26e-8 Bipolar disorder; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02951021 chr12:120934296 DYNLL1 -0.43 -6.38 -0.33 5.65e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2404602 0.716 rs284895 chr15:76751225 C/G cg23625390 chr15:77176239 SCAPER -0.38 -6.31 -0.32 8.67e-10 Blood metabolite levels; LIHC cis rs67311347 0.911 rs6775936 chr3:40377399 T/G cg13409248 chr3:40428643 ENTPD3 0.4 6.51 0.33 2.64e-10 Renal cell carcinoma; LIHC cis rs6061231 0.798 rs2427308 chr20:60969451 C/T cg22601191 chr20:60968625 CABLES2 0.45 5.8 0.3 1.54e-8 Colorectal cancer; LIHC cis rs7940866 0.774 rs12420126 chr11:130834811 C/T cg12179176 chr11:130786555 SNX19 0.62 9.0 0.44 1.56e-17 Schizophrenia; LIHC cis rs9640161 0.742 rs2159235 chr7:150017228 T/C cg17279839 chr7:150038598 RARRES2 0.5 10.72 0.5 2.57e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs1707322 0.656 rs3014210 chr1:46066608 A/G cg06784218 chr1:46089804 CCDC17 -0.41 -7.45 -0.37 7.79e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs877282 0.898 rs12354872 chr10:763362 G/A cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs11969893 0.737 rs9498439 chr6:101404768 A/T cg12253828 chr6:101329408 ASCC3 0.97 12.07 0.55 3.61e-28 Economic and political preferences (immigration/crime); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26716323 chr7:22862328 TOMM7 0.5 6.89 0.35 2.7e-11 Pancreatic cancer; LIHC cis rs9303401 0.527 rs12939313 chr17:56755616 A/T cg25039879 chr17:56429692 SUPT4H1 0.81 8.45 0.42 8.63e-16 Cognitive test performance; LIHC cis rs9300255 0.544 rs1727310 chr12:123660510 A/G cg00376283 chr12:123451042 ABCB9 0.58 5.72 0.3 2.33e-8 Neutrophil percentage of white cells; LIHC cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg13047869 chr3:10149882 C3orf24 0.55 6.93 0.35 2.08e-11 Alzheimer's disease; LIHC cis rs9733 0.635 rs486836 chr1:150875967 A/T cg18016565 chr1:150552671 MCL1 -0.5 -9.37 -0.45 1.04e-18 Tonsillectomy; LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg00106254 chr7:1943704 MAD1L1 -0.49 -8.09 -0.4 1.02e-14 Bipolar disorder and schizophrenia; LIHC cis rs9614461 0.609 rs9614653 chr22:45767391 A/G cg13318129 chr22:45737514 FAM118A -0.5 -7.59 -0.38 3.04e-13 Tonsillectomy; LIHC cis rs9640161 0.789 rs28439010 chr7:150046276 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.45 -7.36 -0.37 1.34e-12 Blood protein levels;Circulating chemerin levels; LIHC cis rs7572733 0.534 rs11899188 chr2:198740121 C/T cg10820045 chr2:198174542 NA 0.46 6.97 0.35 1.68e-11 Dermatomyositis; LIHC cis rs7131987 0.621 rs6487805 chr12:29457550 A/T cg05697976 chr12:29376483 FAR2 -0.29 -5.98 -0.31 5.69e-9 QT interval; LIHC cis rs12602486 1.000 rs12601855 chr17:42224023 A/G cg13607699 chr17:42295918 UBTF -0.72 -6.27 -0.32 1.12e-9 Glycated hemoglobin levels; LIHC cis rs9858542 0.953 rs9878943 chr3:49434654 G/A cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs992157 0.732 rs10932771 chr2:219170236 A/T cg20019365 chr2:219134978 PNKD;AAMP 0.79 12.84 0.57 4.55e-31 Colorectal cancer; LIHC cis rs77106637 1.000 rs76793820 chr11:72619860 G/A cg03713592 chr11:72463424 ARAP1 0.79 6.78 0.34 5.18e-11 Type 2 diabetes; LIHC cis rs2404602 0.710 rs2469541 chr15:76562118 C/T cg23625390 chr15:77176239 SCAPER -0.38 -6.62 -0.34 1.43e-10 Blood metabolite levels; LIHC cis rs4076764 0.914 rs6689760 chr1:163358704 A/G cg24596788 chr1:163392923 NA 0.21 6.82 0.35 4.23e-11 Motion sickness; LIHC cis rs10861342 1.000 rs115224406 chr12:105578060 C/T cg23923672 chr12:105501055 KIAA1033 0.68 7.98 0.4 2.26e-14 IgG glycosylation; LIHC cis rs9303401 0.614 rs34678056 chr17:57177549 G/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.92 0.43 2.77e-17 Cognitive test performance; LIHC cis rs1552244 0.882 rs2130813 chr3:10038706 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.77 10.28 0.49 8.86e-22 Alzheimer's disease; LIHC trans rs79976124 0.760 rs74295030 chr6:66654441 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.77 0.34 5.54e-11 Type 2 diabetes; LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg14893161 chr1:205819251 PM20D1 0.81 11.77 0.54 4.57e-27 Menarche (age at onset); LIHC cis rs743757 1.000 rs6446206 chr3:50455470 G/A cg05260129 chr3:50388622 TUSC4;CYB561D2 0.42 5.83 0.3 1.32e-8 Diastolic blood pressure; LIHC cis rs7223966 1.000 rs55868506 chr17:61851686 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.94 0.35 1.95e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg11764359 chr7:65958608 NA 0.56 5.87 0.3 1.05e-8 Diabetic kidney disease; LIHC cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg11644478 chr21:40555479 PSMG1 -0.45 -7.07 -0.36 9.03e-12 Cognitive function; LIHC cis rs6424115 0.729 rs561733 chr1:24049595 T/G cg15997130 chr1:24165203 NA 0.31 6.39 0.33 5.45e-10 Immature fraction of reticulocytes; LIHC cis rs9309473 1.000 rs7586463 chr2:73798476 T/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs1801251 0.963 rs283481 chr2:233648091 A/G cg08000102 chr2:233561755 GIGYF2 0.77 11.71 0.54 7.17e-27 Coronary artery disease; LIHC cis rs4780401 0.609 rs35902600 chr16:11800848 C/T cg01061890 chr16:11836724 TXNDC11 -0.64 -10.13 -0.48 2.98e-21 Rheumatoid arthritis; LIHC cis rs597539 0.652 rs584108 chr11:68630282 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.76 -10.79 -0.5 1.46e-23 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1801251 1.000 rs2592113 chr2:233669553 C/T cg25237894 chr2:233734115 C2orf82 0.58 11.46 0.53 5.78e-26 Coronary artery disease; LIHC trans rs4799915 1.000 rs3865391 chr18:34929280 C/T cg11874882 chr17:31910113 ACCN1 -0.28 -6.53 -0.33 2.38e-10 Response to iloperidone treatment (QT prolongation); LIHC cis rs2153535 0.580 rs6597318 chr6:8437289 G/A cg07606381 chr6:8435919 SLC35B3 0.77 11.76 0.54 4.78e-27 Motion sickness; LIHC cis rs1198430 0.639 rs685059 chr1:23783185 C/G cg13183780 chr1:23809682 ASAP3 -0.38 -6.54 -0.33 2.21e-10 Total cholesterol levels; LIHC cis rs7172677 0.768 rs2304901 chr15:75340722 G/A cg17294928 chr15:75287854 SCAMP5 0.46 6.19 0.32 1.68e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9790314 1.000 rs9872514 chr3:161042833 T/C cg04691961 chr3:161091175 C3orf57 -0.34 -6.01 -0.31 4.81e-9 Morning vs. evening chronotype; LIHC cis rs651907 0.513 rs34963630 chr3:101504817 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.28 0.49 8.95e-22 Colorectal cancer; LIHC cis rs17152411 0.895 rs7900929 chr10:126584999 A/C cg07906193 chr10:126599966 NA 0.38 6.26 0.32 1.18e-9 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23151374 chr4:164415611 C4orf43 0.38 6.39 0.33 5.55e-10 Cognitive function; LIHC cis rs797680 0.789 rs531514 chr1:93700212 C/T cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.89 0.3 9.29e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC trans rs11098499 0.908 rs1002152 chr4:120273387 C/A cg25214090 chr10:38739885 LOC399744 0.56 9.09 0.44 8.02e-18 Corneal astigmatism; LIHC cis rs17854409 0.764 rs3761301 chr20:61494021 C/T cg06598544 chr20:61472147 COL9A3 -0.87 -7.36 -0.37 1.39e-12 Obesity-related traits; LIHC cis rs7131987 0.903 rs7974221 chr12:29399448 A/G cg14222432 chr12:29376421 FAR2 0.38 7.32 0.37 1.75e-12 QT interval; LIHC cis rs2439831 0.867 rs2245715 chr15:43818052 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.55 7.4 0.37 1.09e-12 Lung cancer in ever smokers; LIHC trans rs2739330 0.828 rs4820572 chr22:24250355 T/C cg06437703 chr8:37914619 EIF4EBP1 -0.53 -8.11 -0.4 9.19e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs67311347 1.000 rs28434528 chr3:40484893 A/G cg09455208 chr3:40491958 NA 0.36 7.4 0.37 1.09e-12 Renal cell carcinoma; LIHC cis rs12477438 0.520 rs720229 chr2:99704273 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.6 11.06 0.51 1.69e-24 Chronic sinus infection; LIHC trans rs11098499 0.954 rs10031665 chr4:120422852 T/C cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs9583531 0.527 rs6492302 chr13:111352354 C/T cg24331049 chr13:111365604 ING1 -0.6 -10.06 -0.48 4.92e-21 Coronary artery disease; LIHC cis rs8141529 0.748 rs6005936 chr22:29289250 T/C cg02153584 chr22:29168773 CCDC117 0.52 8.05 0.4 1.34e-14 Lymphocyte counts; LIHC cis rs7927771 0.524 rs10838769 chr11:47825333 A/G cg20307385 chr11:47447363 PSMC3 -0.66 -9.97 -0.47 1.01e-20 Subjective well-being; LIHC cis rs67311347 1.000 rs9874006 chr3:40471596 G/A cg24209194 chr3:40518798 ZNF619 0.49 7.37 0.37 1.32e-12 Renal cell carcinoma; LIHC cis rs748404 0.660 rs693510 chr15:43714625 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.15 0.36 5.42e-12 Lung cancer; LIHC cis rs2463822 1.000 rs72921498 chr11:62113090 C/T cg06239285 chr11:62104954 ASRGL1 -0.94 -7.0 -0.35 1.32e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2832191 0.791 rs2832199 chr21:30498501 G/A cg08807101 chr21:30365312 RNF160 -0.57 -8.87 -0.43 4.04e-17 Dental caries; LIHC cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.43 6.06 0.31 3.63e-9 Electroencephalogram traits; LIHC cis rs7412746 0.658 rs6669855 chr1:150861229 C/T cg15448220 chr1:150897856 SETDB1 0.39 6.14 0.31 2.35e-9 Melanoma; LIHC cis rs34779708 0.733 rs7087099 chr10:35541982 C/T cg03585969 chr10:35415529 CREM 0.76 11.0 0.51 2.6e-24 Inflammatory bowel disease;Crohn's disease; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg20225246 chr19:2200020 DOT1L 0.47 6.95 0.35 1.86e-11 Bilirubin levels; LIHC cis rs3008870 1.000 rs3008848 chr1:67379284 C/T cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.29e-8 Lymphocyte percentage of white cells; LIHC cis rs9790314 0.690 rs7617204 chr3:160821969 A/G cg03342759 chr3:160939853 NMD3 -0.71 -10.81 -0.5 1.23e-23 Morning vs. evening chronotype; LIHC cis rs853679 0.517 rs4713137 chr6:28083521 C/G cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs2997447 0.846 rs12067677 chr1:26411971 C/T cg19633962 chr1:26362018 EXTL1 -0.59 -6.93 -0.35 2.09e-11 QRS complex (12-leadsum); LIHC cis rs734999 0.545 rs10910111 chr1:2542653 A/G cg20673091 chr1:2541236 MMEL1 0.27 5.73 0.3 2.18e-8 Ulcerative colitis; LIHC cis rs5769707 0.967 rs1018812 chr22:50010073 C/T cg01652190 chr22:50026171 C22orf34 -0.3 -6.9 -0.35 2.57e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs4665809 0.941 rs6735145 chr2:26270302 T/C cg27170947 chr2:26402098 FAM59B -0.62 -7.57 -0.38 3.4e-13 Gut microbiome composition (summer); LIHC cis rs6545883 0.894 rs2694642 chr2:61596180 A/G cg14146966 chr2:61757674 XPO1 -0.44 -7.31 -0.37 1.91e-12 Tuberculosis; LIHC cis rs13191362 1.000 rs67046187 chr6:163068532 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.76 6.53 0.33 2.31e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7927771 0.756 rs10742803 chr11:47439938 A/G cg20307385 chr11:47447363 PSMC3 0.5 6.47 0.33 3.31e-10 Subjective well-being; LIHC cis rs6754311 0.773 rs309176 chr2:136622216 T/C cg17750252 chr2:136567154 LCT 0.33 6.16 0.32 2.01e-9 Mosquito bite size; LIHC cis rs796364 0.806 rs188102 chr2:200903189 T/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.78 -8.65 -0.42 1.97e-16 Schizophrenia; LIHC cis rs61990749 0.597 rs4632066 chr14:78247282 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.27 -0.49 9.9e-22 Fibroblast growth factor basic levels; LIHC cis rs2153535 0.580 rs9406158 chr6:8464152 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC trans rs10411161 0.702 rs7251571 chr19:52389057 A/G cg22319618 chr22:45562946 NUP50 -0.61 -8.56 -0.42 3.75e-16 Breast cancer; LIHC cis rs344364 0.511 rs2982455 chr16:1950498 T/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.29 -0.37 2.1e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.27 -0.45 2.15e-18 Intelligence (multi-trait analysis); LIHC cis rs7617480 0.648 rs9864243 chr3:48982732 G/A cg07636037 chr3:49044803 WDR6 0.75 8.97 0.44 1.99e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs2439831 0.867 rs7170489 chr15:43636651 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC cis rs9325144 0.555 rs1973292 chr12:38679626 T/C cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.42e-14 Morning vs. evening chronotype; LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg23990641 chr6:118823964 C6orf204;BRD7P3 0.44 5.97 0.31 5.95e-9 Diastolic blood pressure; LIHC cis rs2380220 0.541 rs72928277 chr6:96079745 G/T cg23517279 chr6:96025343 MANEA -0.61 -6.25 -0.32 1.23e-9 Behavioural disinhibition (generation interaction); LIHC cis rs10416265 0.527 rs7246814 chr19:33538414 G/T cg27124370 chr19:33622961 WDR88 0.56 8.13 0.4 8.02e-15 Bone properties (heel); LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg11494091 chr17:61959527 GH2 0.36 5.98 0.31 5.77e-9 Height; LIHC cis rs3791556 0.898 rs3791549 chr2:240109024 A/G cg03281426 chr2:240109471 HDAC4 -0.4 -6.49 -0.33 3.07e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8053891 0.813 rs16973520 chr16:71996291 T/G cg01557791 chr16:72042693 DHODH -0.42 -6.17 -0.32 1.91e-9 Coronary artery disease; LIHC trans rs1005277 0.579 rs2505240 chr10:38442419 G/T cg27523141 chr10:43048294 ZNF37B 0.37 6.27 0.32 1.11e-9 Extrinsic epigenetic age acceleration; LIHC cis rs738321 0.756 rs12169611 chr22:38513735 T/C cg25457927 chr22:38595422 NA -0.29 -6.46 -0.33 3.53e-10 Breast cancer; LIHC cis rs9517320 0.515 rs61969456 chr13:99174799 C/G cg20487152 chr13:99095054 FARP1 -0.37 -6.22 -0.32 1.42e-9 Longevity; LIHC cis rs4819052 0.851 rs2838865 chr21:46712299 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 11.64 0.53 1.33e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12926788 0.546 rs200531 chr16:24756172 G/A cg04756594 chr16:24857601 SLC5A11 -0.6 -9.05 -0.44 1.08e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4843747 0.671 rs8062855 chr16:88106941 T/C cg06050784 chr16:88016603 BANP 0.36 6.57 0.33 1.93e-10 Menopause (age at onset); LIHC cis rs2933343 0.729 rs6767104 chr3:128648117 G/T cg25356066 chr3:128598488 ACAD9 -0.53 -7.29 -0.37 2.18e-12 IgG glycosylation; LIHC cis rs9868809 0.505 rs11708786 chr3:48752654 C/T cg00383909 chr3:49044727 WDR6 0.63 5.82 0.3 1.38e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs6976053 0.541 rs314359 chr7:100411278 T/C cg01903971 chr7:100434983 NA -0.39 -6.35 -0.32 6.79e-10 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg16103275 chr6:290800 DUSP22 0.5 6.44 0.33 4.08e-10 Menopause (age at onset); LIHC cis rs6089829 0.925 rs6062396 chr20:61667949 T/C cg03213289 chr20:61660250 NA 0.51 9.01 0.44 1.48e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs4684776 1.000 rs7645555 chr3:11416009 T/G cg00170343 chr3:11313890 ATG7 -0.43 -5.81 -0.3 1.45e-8 Small vessel stroke; LIHC cis rs2204008 0.837 rs2387317 chr12:38235319 T/C cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC trans rs2727020 0.521 rs10839285 chr11:49496852 T/G cg18944383 chr4:111397179 ENPEP -0.34 -8.2 -0.41 4.77e-15 Coronary artery disease; LIHC cis rs57590327 0.555 rs13088603 chr3:81791167 A/G cg07356753 chr3:81810745 GBE1 -0.58 -8.96 -0.44 2.07e-17 Extraversion; LIHC cis rs225245 0.755 rs8078905 chr17:34009029 T/C cg05299278 chr17:33885742 SLFN14 0.23 6.34 0.32 7.1e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.673 rs73265633 chr17:29236306 G/T cg14067834 chr17:29058358 SUZ12P 0.69 6.65 0.34 1.16e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10791097 0.667 rs2155358 chr11:130740357 T/C cg12179176 chr11:130786555 SNX19 0.81 13.05 0.58 7.15e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs983392 0.709 rs1349667 chr11:59993346 T/A cg17275991 chr19:58003312 ZNF419 0.43 6.06 0.31 3.64e-9 Alzheimer's disease (late onset); LIHC cis rs1882538 0.503 rs1345938 chr7:133137867 C/T cg10665199 chr7:133106180 EXOC4 -0.5 -8.07 -0.4 1.18e-14 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.803 rs11040451 chr11:49650639 C/T cg03929089 chr4:120376271 NA -0.88 -16.9 -0.67 5.32e-47 Height; LIHC cis rs5770917 1.000 rs3180872 chr22:51017394 G/C cg08260245 chr22:51016501 CPT1B;CHKB-CPT1B -0.4 -5.82 -0.3 1.38e-8 Narcolepsy; LIHC cis rs62380364 0.602 rs589544 chr5:88064462 T/C cg22951263 chr5:87985283 NA -0.41 -7.17 -0.36 4.71e-12 Intelligence (multi-trait analysis); LIHC cis rs10744422 1.000 rs4759355 chr12:123316566 A/G cg22842854 chr12:123319900 HIP1R -0.67 -8.8 -0.43 7.1e-17 Schizophrenia; LIHC cis rs17286411 0.750 rs4788575 chr16:71931126 T/G cg03805757 chr16:71968109 PKD1L3 0.42 5.89 0.3 9.23e-9 Blood protein levels; LIHC cis rs76419734 0.510 rs7659526 chr4:106621643 T/C cg24545054 chr4:106630052 GSTCD;INTS12 0.78 9.04 0.44 1.17e-17 Post bronchodilator FEV1; LIHC cis rs9583531 0.600 rs4773240 chr13:111360585 G/A cg24331049 chr13:111365604 ING1 0.78 13.14 0.58 3.32e-32 Coronary artery disease; LIHC cis rs593982 0.858 rs663797 chr11:65552740 A/G cg08755490 chr11:65554678 OVOL1 0.57 8.62 0.42 2.61e-16 Atopic dermatitis; LIHC cis rs875971 0.862 rs778680 chr7:65840414 G/A cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22748539 chr11:68830527 TPCN2 0.4 6.26 0.32 1.16e-9 Pancreatic cancer; LIHC cis rs6546550 0.901 rs4144081 chr2:70155482 G/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.53 -0.38 4.64e-13 Prevalent atrial fibrillation; LIHC cis rs11098499 0.739 rs2203039 chr4:120132347 T/C cg09307838 chr4:120376055 NA -0.49 -7.54 -0.38 4.38e-13 Corneal astigmatism; LIHC cis rs78456975 1.000 rs13422995 chr2:1553554 C/A cg01028140 chr2:1542097 TPO -0.53 -6.34 -0.32 7.32e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1059312 0.808 rs4482069 chr12:129294252 G/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.78 -16.98 -0.68 2.56e-47 Systemic lupus erythematosus; LIHC cis rs8060686 0.623 rs7205935 chr16:68152157 A/G cg05110241 chr16:68378359 PRMT7 -0.5 -5.95 -0.31 6.56e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs1499614 1.000 rs34250985 chr7:66161062 A/T cg10756647 chr7:56101905 PSPH 0.95 9.96 0.47 1.08e-20 Gout; LIHC cis rs1691799 0.899 rs1168321 chr12:66744517 C/G cg16791601 chr12:66731901 HELB 0.56 13.83 0.6 7.33e-35 White blood cell count (basophil); LIHC cis rs4808199 0.739 rs2240117 chr19:19418916 C/T cg10763598 chr19:19431466 KIAA0892;SF4 0.5 5.78 0.3 1.72e-8 Nonalcoholic fatty liver disease; LIHC cis rs2303759 0.918 rs4802597 chr19:49872085 C/T cg22590775 chr19:49891494 CCDC155 0.45 7.4 0.37 1.05e-12 Multiple sclerosis; LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg06601766 chr17:61851465 DDX42;CCDC47 -0.39 -6.01 -0.31 4.71e-9 Prudent dietary pattern; LIHC cis rs597539 0.652 rs488363 chr11:68658298 C/G cg04772025 chr11:68637568 NA 0.47 6.26 0.32 1.12e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs1005277 0.589 rs2749624 chr10:38529865 A/G cg27523141 chr10:43048294 ZNF37B 0.4 6.73 0.34 7.23e-11 Extrinsic epigenetic age acceleration; LIHC cis rs9325144 0.560 rs11183150 chr12:38674698 A/G cg26384229 chr12:38710491 ALG10B -0.6 -8.17 -0.4 5.85e-15 Morning vs. evening chronotype; LIHC cis rs7575873 1 rs7575873 chr2:23962647 A/G cg08917208 chr2:24149416 ATAD2B 0.95 8.12 0.4 8.61e-15 Birth weight; LIHC cis rs10870270 0.956 rs7894 chr10:133769482 G/C cg26149184 chr10:133730230 NA 0.47 7.48 0.37 6.29e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.7.2226368R chr7:103835598 ORC5L -0.36 -6.15 -0.32 2.12e-9 Cognitive function; LIHC cis rs7264396 0.635 rs6058351 chr20:34486093 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.54 -0.5 1.08e-22 Total cholesterol levels; LIHC cis rs6748734 1.000 rs4311055 chr2:241821017 T/C cg04034577 chr2:241836375 C2orf54 -0.37 -7.3 -0.37 2.09e-12 Urinary metabolites; LIHC cis rs7959452 0.590 rs6581889 chr12:69757429 T/C cg14784868 chr12:69753453 YEATS4 0.95 20.54 0.74 1.24e-61 Blood protein levels; LIHC cis rs17685 0.753 rs10264760 chr7:75749694 A/G cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.48e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs700651 0.789 rs1976772 chr2:198868201 G/T cg10820045 chr2:198174542 NA 0.45 6.73 0.34 7.37e-11 Intracranial aneurysm; LIHC cis rs7633770 0.786 rs4234464 chr3:46679675 C/T cg11219411 chr3:46661640 NA -0.44 -7.91 -0.39 3.68e-14 Coronary artery disease; LIHC cis rs8072100 0.537 rs9912450 chr17:45402208 C/T cg08085267 chr17:45401833 C17orf57 -0.62 -9.47 -0.46 4.9e-19 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09328466 chr7:64023458 ZNF680 -0.43 -6.46 -0.33 3.6e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4268898 0.552 rs12620938 chr2:24367122 C/A cg06627628 chr2:24431161 ITSN2 0.46 6.69 0.34 8.94e-11 Asthma; LIHC cis rs10492096 1.000 rs10849462 chr12:6575992 C/T cg13857086 chr12:6580257 VAMP1 0.59 6.02 0.31 4.42e-9 Hip geometry; LIHC cis rs1005277 0.579 rs2472176 chr10:38382921 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3812831 0.643 rs7322339 chr13:114929726 C/A cg06611532 chr13:114900021 NA 0.43 7.87 0.39 4.77e-14 Schizophrenia; LIHC cis rs10454142 1.000 rs10454142 chr2:48646399 T/C cg15846641 chr2:48541264 FOXN2 0.46 6.03 0.31 4.31e-9 Sex hormone-binding globulin levels; LIHC cis rs3020736 0.500 rs6002604 chr22:42493081 A/T cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs8077889 1.000 rs113919636 chr17:41877740 A/C cg26893861 chr17:41843967 DUSP3 0.89 9.87 0.47 2.27e-20 Triglycerides; LIHC cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.79 -0.34 5.03e-11 Gut microbiome composition (summer); LIHC cis rs7091068 0.671 rs620890 chr10:95405424 G/A cg20715218 chr10:95462985 C10orf4 -0.6 -6.87 -0.35 3.04e-11 Urinary tract infection frequency; LIHC cis rs6442522 0.550 rs4036833 chr3:15406428 G/C cg16303742 chr3:15540471 COLQ 0.4 6.84 0.35 3.64e-11 Uric acid levels; LIHC cis rs8072100 0.817 rs12449647 chr17:45548958 C/A cg08085267 chr17:45401833 C17orf57 -0.44 -6.5 -0.33 2.83e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg19318889 chr4:1322082 MAEA -0.48 -7.92 -0.39 3.27e-14 Obesity-related traits; LIHC cis rs35955747 0.902 rs12167361 chr22:31696278 G/C cg22777020 chr22:31556080 RNF185 -0.49 -5.76 -0.3 1.91e-8 Neutrophil count;Sum basophil neutrophil counts; LIHC cis rs1707322 0.686 rs1084086 chr1:46041100 A/C cg03146154 chr1:46216737 IPP -0.55 -8.8 -0.43 7.02e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10540 1.000 rs61876341 chr11:495892 C/G cg03576123 chr11:487126 PTDSS2 -1.12 -8.41 -0.41 1.13e-15 Body mass index; LIHC cis rs12101261 1.000 rs8003061 chr14:81451956 G/A cg06600135 chr14:81408086 NA 0.37 6.3 0.32 8.99e-10 Graves' disease; LIHC cis rs1670533 0.932 rs13108207 chr4:1054218 C/T cg27284194 chr4:1044797 NA 0.6 8.88 0.43 3.79e-17 Recombination rate (females); LIHC trans rs2243480 1.000 rs10950032 chr7:65738591 C/A cg10756647 chr7:56101905 PSPH -1.03 -12.48 -0.56 1.05e-29 Diabetic kidney disease; LIHC cis rs7508679 1.000 rs7508679 chr19:7222832 A/G cg09779027 chr19:7224513 INSR 0.29 6.75 0.34 6.17e-11 Hypothyroidism; LIHC cis rs4631830 0.540 rs2843562 chr10:51496796 A/G cg16070123 chr10:51489643 NA 0.38 6.12 0.31 2.54e-9 Prostate-specific antigen levels; LIHC cis rs3736485 0.966 rs8031903 chr15:51838161 C/T cg08986416 chr15:51914746 DMXL2 -0.41 -6.07 -0.31 3.49e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11249189 chr17:42148592 G6PC3 0.41 6.12 0.31 2.5e-9 Cognitive function; LIHC cis rs2292096 1.000 rs12747799 chr1:200717686 A/T cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.12 -0.31 2.57e-9 Epilepsy; LIHC cis rs10845606 0.581 rs10772591 chr12:12834802 A/G cg09462578 chr12:12878428 APOLD1 -0.49 -7.41 -0.37 1.02e-12 Systemic lupus erythematosus; LIHC trans rs1005277 0.638 rs1005278 chr10:38218748 G/A cg17830980 chr10:43048298 ZNF37B 0.38 6.87 0.35 2.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs1707322 0.691 rs28495425 chr1:46187320 T/G cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6500602 0.627 rs934929 chr16:4587789 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.45 -6.57 -0.33 1.93e-10 Schizophrenia; LIHC cis rs9309473 1.000 rs7598419 chr2:73798223 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.53 -0.33 2.32e-10 Metabolite levels; LIHC cis rs12824058 0.831 rs4759657 chr12:130815818 G/A cg26677194 chr12:130822605 PIWIL1 0.51 7.17 0.36 4.52e-12 Menopause (age at onset); LIHC cis rs7772486 0.790 rs2265918 chr6:146219164 A/G cg23711669 chr6:146136114 FBXO30 0.63 11.05 0.51 1.77e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088590 1.000 rs6119516 chr20:33328024 C/T cg24642439 chr20:33292090 TP53INP2 0.79 11.29 0.52 2.5e-25 Coronary artery disease; LIHC cis rs10504229 1.000 rs10504229 chr8:58196495 A/G cg20607798 chr8:58055168 NA 0.57 6.65 0.34 1.13e-10 Developmental language disorder (linguistic errors); LIHC cis rs9768139 0.566 rs729099 chr7:158114152 C/T cg06219351 chr7:158114137 PTPRN2 -0.22 -6.27 -0.32 1.07e-9 Calcium levels; LIHC cis rs614226 1.000 rs563920 chr12:121017439 A/G cg01236616 chr12:121019343 POP5 1.23 18.11 0.7 7.3e-52 Type 1 diabetes nephropathy; LIHC cis rs8114671 0.836 rs2425006 chr20:33571228 T/G cg07148914 chr20:33460835 GGT7 -0.59 -9.12 -0.44 6.34e-18 Height; LIHC cis rs6424115 0.708 rs13551 chr1:24180962 T/C cg08896387 chr1:24191740 FUCA1 0.38 6.05 0.31 3.89e-9 Immature fraction of reticulocytes; LIHC cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg03806693 chr22:41940476 POLR3H 1.12 12.79 0.57 7.08e-31 Vitiligo; LIHC cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs782590 0.608 rs10207590 chr2:55921782 G/C cg03859395 chr2:55845619 SMEK2 -0.51 -8.71 -0.43 1.29e-16 Metabolic syndrome; LIHC cis rs11662586 1.000 rs12605316 chr18:77693600 C/T cg20368463 chr18:77673604 PQLC1 0.43 6.7 0.34 8.66e-11 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs8180040 0.620 rs6767907 chr3:47162661 C/T cg16586182 chr3:47516702 SCAP 0.48 8.65 0.42 1.98e-16 Colorectal cancer; LIHC cis rs2274273 0.840 rs7159144 chr14:55821324 G/A cg01864836 chr14:55583639 NA -0.4 -7.52 -0.38 4.98e-13 Protein biomarker; LIHC cis rs6456156 0.792 rs4710179 chr6:167513692 G/T cg07741184 chr6:167504864 NA 0.28 6.89 0.35 2.69e-11 Primary biliary cholangitis; LIHC cis rs10751667 0.643 rs7394436 chr11:970373 G/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs651907 0.557 rs34457525 chr3:101435225 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.46 0.53 5.85e-26 Colorectal cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg10998122 chr11:64008466 FKBP2 0.43 6.1 0.31 2.88e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12744310 0.887 rs12047161 chr1:41807528 G/T cg03962019 chr1:41807865 NA 0.39 6.28 0.32 1.05e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6977660 1.000 rs57916046 chr7:19800542 T/C cg07541023 chr7:19748670 TWISTNB 0.41 6.34 0.32 7.43e-10 Thyroid stimulating hormone; LIHC cis rs12477438 0.834 rs1563106 chr2:99701381 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -10.57 -0.5 8.92e-23 Chronic sinus infection; LIHC cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg00684032 chr4:1343700 KIAA1530 0.5 7.33 0.37 1.71e-12 Obesity-related traits; LIHC cis rs1949733 1.000 rs1916326 chr4:8500023 G/A cg11789530 chr4:8429930 ACOX3 -0.78 -11.79 -0.54 3.59e-27 Response to antineoplastic agents; LIHC cis rs35110281 0.782 rs2838329 chr21:45023329 T/C cg04455712 chr21:45112962 RRP1B 0.48 8.2 0.41 4.97e-15 Mean corpuscular volume; LIHC cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg00149659 chr3:10157352 C3orf10 0.68 7.1 0.36 7.41e-12 Alzheimer's disease; LIHC cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg08677398 chr8:58056175 NA 0.37 6.67 0.34 1.02e-10 Developmental language disorder (linguistic errors); LIHC cis rs6138458 1.000 rs227621 chr20:24910528 A/C cg26195577 chr20:24973756 C20orf3 1.13 14.83 0.63 9.14e-39 Blood protein levels; LIHC cis rs17253792 0.822 rs78820104 chr14:56068854 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg12463550 chr7:65579703 CRCP 0.73 7.14 0.36 5.8e-12 Diabetic kidney disease; LIHC cis rs2979489 0.891 rs4285443 chr8:30327317 A/G cg26383811 chr8:30366931 RBPMS -0.75 -12.91 -0.57 2.39e-31 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg02782426 chr3:40428986 ENTPD3 0.34 6.4 0.33 5e-10 Renal cell carcinoma; LIHC cis rs10503871 0.625 rs13256027 chr8:30305180 G/A cg26383811 chr8:30366931 RBPMS 0.4 6.86 0.35 3.28e-11 Metabolite levels (X-11787); LIHC cis rs4908768 0.906 rs10492966 chr1:8598005 C/T cg25722041 chr1:8623473 RERE 0.41 5.93 0.31 7.22e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg11494091 chr17:61959527 GH2 -0.41 -7.36 -0.37 1.4e-12 Prudent dietary pattern; LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg03721293 chr16:90014378 DEF8 0.41 6.81 0.35 4.5e-11 Skin colour saturation; LIHC cis rs11690935 0.959 rs6738445 chr2:172599615 T/C cg13550731 chr2:172543902 DYNC1I2 0.89 17.2 0.68 3.37e-48 Schizophrenia; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs7707921 0.723 rs226197 chr5:81574925 G/A cg15871215 chr5:81402204 ATG10 0.68 8.17 0.4 6.13e-15 Breast cancer; LIHC cis rs7662987 0.517 rs1154406 chr4:100008494 T/C cg13256891 chr4:100009986 ADH5 0.56 5.77 0.3 1.81e-8 Smoking initiation; LIHC cis rs10751667 1.000 rs10794357 chr11:973374 T/C cg10932868 chr11:921992 NA 0.36 6.72 0.34 7.46e-11 Alzheimer's disease (late onset); LIHC cis rs4665809 1.000 rs6546744 chr2:26302161 A/G cg27170947 chr2:26402098 FAM59B -0.62 -7.71 -0.38 1.37e-13 Gut microbiome composition (summer); LIHC cis rs4803468 0.967 rs4802116 chr19:41905540 C/T cg14132834 chr19:41945861 ATP5SL -0.44 -6.6 -0.34 1.61e-10 Height; LIHC cis rs7739232 0.920 rs77374381 chr6:53530662 A/G cg15658676 chr6:53530538 KLHL31 -1.03 -7.33 -0.37 1.7e-12 Hip circumference adjusted for BMI; LIHC cis rs9649465 0.967 rs12706546 chr7:123353414 G/A cg03229431 chr7:123269106 ASB15 -0.37 -7.95 -0.39 2.77e-14 Migraine; LIHC cis rs17401966 0.838 rs1538557 chr1:10297230 T/C cg19773385 chr1:10388646 KIF1B -0.39 -7.16 -0.36 4.84e-12 Hepatocellular carcinoma; LIHC cis rs2404602 1.000 rs12443137 chr15:76840832 G/T cg23625390 chr15:77176239 SCAPER 0.4 6.74 0.34 6.68e-11 Blood metabolite levels; LIHC cis rs2274273 0.529 rs7149965 chr14:55508191 G/A cg01864836 chr14:55583639 NA -0.36 -5.87 -0.3 1.02e-8 Protein biomarker; LIHC cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg18252515 chr7:66147081 NA 1.13 15.25 0.64 2.08e-40 Diabetic kidney disease; LIHC cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg22963979 chr7:1858916 MAD1L1 -0.38 -6.08 -0.31 3.21e-9 Schizophrenia; LIHC cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.64e-30 Menopause (age at onset); LIHC cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg25204440 chr1:209979598 IRF6 0.5 7.8 0.39 7.47e-14 Cleft lip with or without cleft palate; LIHC cis rs2066819 1.000 rs77032009 chr12:56679971 A/G cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC trans rs11689435 0.925 rs7420802 chr2:218351314 T/C cg13544946 chr9:35729779 TLN1 -0.43 -6.27 -0.32 1.12e-9 Metabolite levels (MHPG); LIHC cis rs208520 0.690 rs851465 chr6:66840293 G/A cg07460842 chr6:66804631 NA -0.8 -8.66 -0.42 1.95e-16 Exhaled nitric oxide output; LIHC cis rs9868809 0.881 rs2310996 chr3:48671834 T/C cg07636037 chr3:49044803 WDR6 -0.52 -6.44 -0.33 4.09e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11008690 chr8:54934459 TCEA1 0.42 6.13 0.31 2.42e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs911119 0.955 rs6036474 chr20:23604414 G/A cg16589663 chr20:23618590 CST3 0.78 8.08 0.4 1.09e-14 Chronic kidney disease; LIHC cis rs6701037 0.748 rs11585368 chr1:175135448 G/A cg00958927 chr1:175162553 KIAA0040 -0.38 -6.16 -0.32 2.08e-9 Alcohol dependence; LIHC cis rs9649213 0.574 rs34817002 chr7:97887051 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.41 -6.23 -0.32 1.4e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs4149468 chr7:65825690 T/C cg12463550 chr7:65579703 CRCP 0.65 6.85 0.35 3.42e-11 Diabetic kidney disease; LIHC cis rs17685 0.753 rs2868203 chr7:75680026 G/A cg16489192 chr7:75678113 MDH2;STYXL1 0.39 6.34 0.32 7.24e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8060686 0.641 rs12447640 chr16:68150527 A/G cg05110241 chr16:68378359 PRMT7 -0.6 -6.78 -0.34 5.16e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs6500602 0.647 rs4786501 chr16:4536165 G/T cg08645402 chr16:4508243 NA -0.44 -8.38 -0.41 1.4e-15 Schizophrenia; LIHC cis rs2204008 0.683 rs11522927 chr12:38137537 C/T cg26384229 chr12:38710491 ALG10B 0.85 10.6 0.5 6.67e-23 Bladder cancer; LIHC cis rs2153535 0.504 rs9405393 chr6:8467432 G/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.63 0.56 2.91e-30 Total body bone mineral density; LIHC trans rs2727020 0.576 rs11040223 chr11:49034633 G/T cg15704280 chr7:45808275 SEPT13 -0.52 -7.96 -0.4 2.57e-14 Coronary artery disease; LIHC cis rs10751667 0.666 rs7483273 chr11:951127 T/C cg10932868 chr11:921992 NA 0.38 7.05 0.36 1.01e-11 Alzheimer's disease (late onset); LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.98 -21.67 -0.76 3.64e-66 Prudent dietary pattern; LIHC cis rs5758659 0.904 rs5758653 chr22:42613485 G/T cg19513890 chr22:42538836 CYP2D7P1 -0.39 -7.62 -0.38 2.44e-13 Cognitive function; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg07677032 chr17:61819896 STRADA 0.44 6.5 0.33 2.88e-10 Prudent dietary pattern; LIHC cis rs12220238 1.000 rs12357530 chr10:75928654 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC cis rs921968 0.541 rs733925 chr2:219302466 G/A cg02985541 chr2:219472218 PLCD4 -0.42 -6.82 -0.35 4.02e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs1797081 0.542 rs2603796 chr10:16871456 C/T cg23933602 chr10:16859644 RSU1 0.66 10.87 0.51 7.44e-24 Platelet distribution width; LIHC cis rs9399135 0.935 rs4273704 chr6:135297520 G/T cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.37e-11 Red blood cell count; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08530205 chr7:101849354 CUX1 0.41 6.12 0.31 2.61e-9 Longevity; LIHC cis rs6964587 0.610 rs7788951 chr7:91468765 A/T cg17063962 chr7:91808500 NA 0.62 10.71 0.5 2.9e-23 Breast cancer; LIHC cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg05535760 chr7:792225 HEATR2 0.93 12.55 0.56 5.75e-30 Cerebrospinal P-tau181p levels; LIHC cis rs7937890 0.559 rs2575852 chr11:14533368 G/A cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs367615 0.704 rs7705399 chr5:108850351 G/C cg17395555 chr5:108820864 NA 0.4 8.8 0.43 7.12e-17 Colorectal cancer (SNP x SNP interaction); LIHC cis rs892961 1.000 rs2164449 chr17:75401190 G/A cg01320579 chr17:75405842 SEPT9 0.5 7.15 0.36 5.46e-12 Airflow obstruction; LIHC cis rs10131894 0.611 rs175002 chr14:75436466 C/G cg08847533 chr14:75593920 NEK9 0.79 14.94 0.63 3.5e-39 Coronary artery disease; LIHC cis rs17685 0.753 rs4573217 chr7:75733946 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.17 -0.32 1.97e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2412488 0.893 rs12511253 chr4:54363801 G/A cg22241045 chr4:54363911 LNX1 0.46 7.61 0.38 2.7e-13 DNA methylation (variation); LIHC cis rs614226 0.688 rs75111771 chr12:121009943 T/C cg01236616 chr12:121019343 POP5 -1.32 -17.01 -0.68 1.81e-47 Type 1 diabetes nephropathy; LIHC cis rs7927592 0.913 rs11228292 chr11:68379772 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.17 -0.32 1.9e-9 Total body bone mineral density; LIHC cis rs80282103 0.618 rs1079389 chr10:1161980 A/G cg08668510 chr10:1095578 IDI1 0.64 6.17 0.32 1.9e-9 Glomerular filtration rate (creatinine); LIHC cis rs611744 0.967 rs677842 chr8:109212468 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg17971929 chr21:40555470 PSMG1 0.52 8.02 0.4 1.74e-14 Cognitive function; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg27072603 chr15:40660990 DISP2 -0.37 -6.18 -0.32 1.79e-9 Calcium levels; LIHC trans rs9323205 0.531 rs55681440 chr14:51542179 T/C cg02322135 chr4:113969312 ANK2 0.42 6.16 0.32 1.99e-9 Cancer; LIHC cis rs139156536 1 rs139156536 chr17:38164432 TTTTA/T cg17467752 chr17:38218738 THRA 0.64 11.84 0.54 2.37e-27 Lymphocyte percentage of white cells; LIHC cis rs1005277 0.540 rs1987431 chr10:37988887 T/C cg00409905 chr10:38381863 ZNF37A -0.57 -9.89 -0.47 1.88e-20 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.94 0.63 3.29e-39 Prudent dietary pattern; LIHC cis rs9649213 0.593 rs11760930 chr7:97915789 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs655641 0.954 rs601185 chr11:85686151 A/T cg09030501 chr11:85779252 PICALM -0.51 -6.14 -0.32 2.23e-9 Platelet count; LIHC cis rs9328573 0.935 rs12900347 chr15:100509459 G/A cg09918751 chr15:100517450 ADAMTS17 -0.47 -7.1 -0.36 7.44e-12 Urate levels in lean individuals; LIHC cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg17971929 chr21:40555470 PSMG1 0.78 9.11 0.44 7.25e-18 Cognitive function; LIHC cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg03264133 chr6:25882463 NA 0.88 12.43 0.56 1.59e-29 Blood metabolite levels; LIHC cis rs2836950 0.565 rs2836945 chr21:40596757 C/T cg06238570 chr21:40685208 BRWD1 -0.42 -6.67 -0.34 1.02e-10 Menarche (age at onset); LIHC cis rs796364 1.000 rs1704186 chr2:200769539 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.7 8.26 0.41 3.34e-15 Schizophrenia; LIHC cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg08822215 chr16:89438651 ANKRD11 -0.41 -6.42 -0.33 4.43e-10 Multiple myeloma (IgH translocation); LIHC cis rs713477 1.000 rs28478984 chr14:55911326 C/A cg13175173 chr14:55914753 NA -0.35 -8.16 -0.4 6.31e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs3845702 0.866 rs3914458 chr2:180862606 A/G cg01881094 chr2:180872142 CWC22 -0.44 -5.72 -0.3 2.27e-8 Schizophrenia; LIHC cis rs7917772 0.582 rs4919663 chr10:104363293 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9911578 0.904 rs7209253 chr17:56908987 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -8.83 -0.43 5.44e-17 Intelligence (multi-trait analysis); LIHC trans rs9940464 0.835 rs4782773 chr16:83369284 C/A cg02755603 chr20:18548475 LOC388789 0.34 6.06 0.31 3.62e-9 Malaria; LIHC cis rs6762477 0.748 rs2073726 chr3:50223593 T/A cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.51 -7.8 -0.39 7.62e-14 Menarche (age at onset); LIHC cis rs1419980 0.730 rs11533526 chr12:7750484 C/T cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs9916302 0.904 rs11078910 chr17:37671269 G/T cg15445000 chr17:37608096 MED1 0.38 5.83 0.3 1.26e-8 Glomerular filtration rate (creatinine); LIHC trans rs526821 0.553 rs295597 chr11:55470003 T/C cg03929089 chr4:120376271 NA -0.45 -6.71 -0.34 7.87e-11 Pediatric bone mineral density (spine); LIHC cis rs2625529 0.816 rs4777467 chr15:72138478 T/C cg16672083 chr15:72433130 SENP8 -0.31 -5.82 -0.3 1.32e-8 Red blood cell count; LIHC cis rs8078723 1.000 rs8070454 chr17:38160754 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.22 -0.45 3.13e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg27286337 chr10:134555280 INPP5A 0.93 13.32 0.58 6.93e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9434723 0.844 rs9434729 chr1:9303940 G/C cg04199779 chr1:9294473 H6PD 0.53 5.94 0.31 6.87e-9 Height; LIHC cis rs45430 1.000 rs416981 chr21:42745414 G/A cg06102954 chr21:42741788 MX2 0.39 6.56 0.33 2e-10 Melanoma; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.71 11.63 0.53 1.47e-26 Prudent dietary pattern; LIHC cis rs12497850 0.931 rs4974087 chr3:48919232 A/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.17 0.36 4.76e-12 Parkinson's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11239145 chr4:26320844 RBPJ 0.46 6.29 0.32 9.98e-10 Lung function (FEV1/FVC); LIHC cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg03264133 chr6:25882463 NA -0.64 -8.06 -0.4 1.29e-14 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.500 rs12829125 chr12:34314789 A/G cg26384229 chr12:38710491 ALG10B 0.57 7.41 0.37 9.8e-13 Morning vs. evening chronotype; LIHC cis rs9918079 0.560 rs12651550 chr4:15641018 G/C cg21329975 chr4:15471214 CC2D2A -0.41 -6.19 -0.32 1.69e-9 Obesity-related traits; LIHC cis rs896854 0.654 rs896846 chr8:95972453 G/A cg16049864 chr8:95962084 TP53INP1 -0.6 -11.49 -0.53 4.52e-26 Type 2 diabetes; LIHC cis rs6840360 0.593 rs4696106 chr4:152606818 A/G cg22705602 chr4:152727874 NA -0.34 -7.05 -0.36 9.96e-12 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.563 rs997147 chr21:40695325 A/G cg17971929 chr21:40555470 PSMG1 -0.43 -6.43 -0.33 4.34e-10 Cognitive function; LIHC cis rs760805 0.965 rs4648883 chr1:25261203 T/C cg22509179 chr1:25234806 RUNX3 -0.37 -7.8 -0.39 7.46e-14 Allergic disease (asthma, hay fever or eczema); LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg18000306 chr6:288505 NA 0.35 6.48 0.33 3.21e-10 Menopause (age at onset); LIHC trans rs61931739 0.500 rs9919726 chr12:34510783 A/G cg26384229 chr12:38710491 ALG10B 0.63 8.12 0.4 8.29e-15 Morning vs. evening chronotype; LIHC cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg06634786 chr22:41940651 POLR3H -0.77 -7.75 -0.39 1.09e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg17330251 chr7:94953956 PON1 -0.65 -12.21 -0.55 1.08e-28 Paraoxonase activity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25632300 chr5:174905618 SFXN1 -0.46 -6.66 -0.34 1.13e-10 Cognitive function; LIHC cis rs1322512 0.917 rs2623956 chr6:152971617 G/A cg03415253 chr6:152958462 SYNE1 -0.33 -5.96 -0.31 6.42e-9 Tonometry; LIHC trans rs561341 1.000 rs55959993 chr17:30254771 C/G cg20587970 chr11:113659929 NA -1.47 -11.82 -0.54 2.81e-27 Hip circumference adjusted for BMI; LIHC cis rs2274273 0.935 rs8004787 chr14:55607366 C/T cg04306507 chr14:55594613 LGALS3 0.33 6.37 0.33 6.21e-10 Protein biomarker; LIHC cis rs3806843 1.000 rs11167600 chr5:140174865 G/C cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.61e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10861342 1.000 rs34705618 chr12:105518611 C/G cg23923672 chr12:105501055 KIAA1033 0.66 7.75 0.39 1.08e-13 IgG glycosylation; LIHC cis rs11098499 0.954 rs3733520 chr4:120423480 C/G cg09307838 chr4:120376055 NA 0.79 12.72 0.57 1.25e-30 Corneal astigmatism; LIHC cis rs10464366 0.746 rs17171537 chr7:39145647 C/T cg21665744 chr7:39171113 POU6F2 0.33 5.99 0.31 5.21e-9 IgG glycosylation; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg11494091 chr17:61959527 GH2 0.41 7.61 0.38 2.74e-13 Prudent dietary pattern; LIHC cis rs34779708 0.649 rs34421369 chr10:35550275 G/C cg03585969 chr10:35415529 CREM 0.74 10.66 0.5 4.27e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3096299 0.869 rs748941 chr16:89440754 T/A cg01788221 chr16:89496183 ANKRD11 -0.42 -6.53 -0.33 2.4e-10 Multiple myeloma (IgH translocation); LIHC cis rs9367716 0.741 rs9396266 chr6:57107322 C/T cg03371099 chr6:57305889 PRIM2 0.35 5.74 0.3 2.14e-8 Coronary artery disease; LIHC cis rs2380220 0.606 rs9488080 chr6:96006973 A/G cg23517279 chr6:96025343 MANEA 0.58 6.64 0.34 1.21e-10 Behavioural disinhibition (generation interaction); LIHC cis rs798554 0.660 rs2527694 chr7:2858240 T/C cg13628971 chr7:2884303 GNA12 0.44 6.96 0.35 1.71e-11 Height; LIHC cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -10.41 -0.49 3.04e-22 Platelet count; LIHC cis rs6448317 0.556 rs4697496 chr4:24907809 C/T cg21108841 chr4:24914750 CCDC149 0.53 6.57 0.33 1.92e-10 Heschl's gyrus morphology; LIHC cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg22800045 chr5:56110881 MAP3K1 0.67 8.58 0.42 3.44e-16 Initial pursuit acceleration; LIHC cis rs35146811 0.844 rs13223792 chr7:99675659 T/G cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.41 5.98 0.31 5.55e-9 Coronary artery disease; LIHC cis rs12477438 0.520 rs11695751 chr2:99708247 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.35 0.64 7.98e-41 Chronic sinus infection; LIHC cis rs9388451 0.874 rs7739566 chr6:126094757 A/T cg06289844 chr6:126071538 HEY2 0.34 5.96 0.31 6.33e-9 Brugada syndrome; LIHC cis rs6912958 0.582 rs242285 chr6:88070743 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.38 7.24 0.36 3.03e-12 Monocyte percentage of white cells; LIHC cis rs9952991 0.941 rs1893217 chr18:12809340 A/G cg23598886 chr18:12777645 NA -0.42 -5.74 -0.3 2.11e-8 Inflammatory skin disease; LIHC cis rs208520 0.955 rs17644076 chr6:67004973 A/G cg07460842 chr6:66804631 NA -0.68 -7.36 -0.37 1.39e-12 Exhaled nitric oxide output; LIHC cis rs7487075 0.823 rs34472481 chr12:46836348 C/G cg22049899 chr12:47219821 SLC38A4 0.33 6.13 0.31 2.38e-9 Itch intensity from mosquito bite; LIHC cis rs6570726 0.935 rs399169 chr6:145836353 C/A cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC trans rs17685 0.712 rs6464994 chr7:75784668 C/T cg19862616 chr7:65841803 NCRNA00174 0.78 14.69 0.62 3.25e-38 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4819052 0.851 rs2255766 chr21:46683777 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.41 0.53 9e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8073060 0.519 rs8065286 chr17:33864479 A/G cg00974761 chr17:33866073 SLFN12L -0.38 -7.61 -0.38 2.69e-13 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7122539 0.646 rs627330 chr11:66602099 C/T cg24851651 chr11:66362959 CCS 0.37 6.39 0.33 5.51e-10 HIV-1 susceptibility; LIHC cis rs763014 0.966 rs15564 chr16:677854 G/T cg07343612 chr16:622815 PIGQ -0.86 -15.69 -0.65 3.44e-42 Height; LIHC cis rs4638749 0.677 rs4396668 chr2:108840364 C/T cg25838818 chr2:108905173 SULT1C2 -0.4 -7.03 -0.36 1.15e-11 Blood pressure; LIHC cis rs1371867 0.817 rs7846076 chr8:101327629 A/G cg06636551 chr8:101224915 SPAG1 -0.46 -8.53 -0.42 4.75e-16 Atrioventricular conduction; LIHC cis rs7937682 0.602 rs4936804 chr11:111743851 A/C cg09085632 chr11:111637200 PPP2R1B 0.96 13.8 0.6 9.84e-35 Primary sclerosing cholangitis; LIHC cis rs2251381 0.722 rs2251278 chr21:30529234 A/G cg24692254 chr21:30365293 RNF160 0.72 10.26 0.48 1.07e-21 Selective IgA deficiency; LIHC cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.7 11.44 0.53 7.03e-26 Colorectal cancer; LIHC trans rs9929218 1.000 rs2113200 chr16:68814948 A/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.55 -7.8 -0.39 7.82e-14 Colorectal cancer; LIHC cis rs5769765 0.773 rs7290751 chr22:50318312 T/C cg09182678 chr22:50328711 NA -0.39 -5.82 -0.3 1.36e-8 Schizophrenia; LIHC cis rs8180040 1.000 rs8180040 chr3:47388947 A/T cg27129171 chr3:47204927 SETD2 0.63 10.68 0.5 3.63e-23 Colorectal cancer; LIHC cis rs1348850 0.645 rs11889272 chr2:178432378 C/T cg27490568 chr2:178487706 NA 0.85 10.35 0.49 5.14e-22 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.76 -13.04 -0.58 7.68e-32 Height; LIHC cis rs28595532 0.545 rs17594782 chr4:119250877 G/T cg21605333 chr4:119757512 SEC24D 0.79 6.65 0.34 1.19e-10 Cannabis dependence symptom count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07063032 chr18:3450262 TGIF1 0.49 6.66 0.34 1.08e-10 Lung function (FEV1/FVC); LIHC cis rs477692 0.569 rs10764887 chr10:131321719 A/T cg05714579 chr10:131428358 MGMT 0.41 6.72 0.34 7.77e-11 Response to temozolomide; LIHC cis rs727563 0.520 rs132773 chr22:42031768 T/A cg06634786 chr22:41940651 POLR3H 0.71 7.38 0.37 1.23e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs6831352 0.840 rs29001223 chr4:100047433 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs9788682 1.000 rs35212593 chr15:78831826 G/A cg06917634 chr15:78832804 PSMA4 -0.55 -7.81 -0.39 7.23e-14 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs9733 0.569 rs11588404 chr1:150688529 C/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg23205692 chr1:25664452 TMEM50A 0.37 5.92 0.31 7.71e-9 Erythrocyte sedimentation rate; LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg26354017 chr1:205819088 PM20D1 0.77 11.46 0.53 6.06e-26 Menarche (age at onset); LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg10755058 chr3:40428713 ENTPD3 0.4 6.87 0.35 3.05e-11 Renal cell carcinoma; LIHC cis rs2153535 0.553 rs2984099 chr6:8637274 C/T cg21535247 chr6:8435926 SLC35B3 -0.69 -9.04 -0.44 1.19e-17 Motion sickness; LIHC cis rs4908768 0.657 rs11121229 chr1:8831283 C/T cg20416874 chr1:8611966 RERE -0.49 -6.68 -0.34 9.8e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13713052 chr3:122102218 FAM162A;CCDC58 0.52 8.04 0.4 1.48e-14 Cognitive function; LIHC cis rs1008375 0.966 rs2872957 chr4:17651757 C/A cg15017067 chr4:17643749 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8038465 0.622 rs7182124 chr15:73915254 C/T cg15420318 chr15:73925796 NPTN 0.49 7.32 0.37 1.79e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs600806 0.813 rs6664236 chr1:109986672 C/A cg23091122 chr1:110024289 SYPL2 -0.52 -6.86 -0.35 3.22e-11 Intelligence (multi-trait analysis); LIHC cis rs249954 0.512 rs7588 chr16:23681165 G/A cg05131483 chr16:23706242 ERN2 0.38 6.16 0.32 2.03e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg17328964 chr8:145687451 CYHR1 -0.57 -10.13 -0.48 2.83e-21 Age at first birth; LIHC cis rs708547 0.647 rs4864609 chr4:57878141 T/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.46 6.75 0.34 6.36e-11 Response to bleomycin (chromatid breaks); LIHC cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg17372223 chr3:52568218 NT5DC2 0.35 5.82 0.3 1.32e-8 Electroencephalogram traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24991452 chr6:35996059 MAPK14 0.48 6.78 0.34 5.34e-11 Pancreatic cancer; LIHC trans rs3783890 1.000 rs12590553 chr14:93737668 T/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.21 0.32 1.56e-9 Body mass index; LIHC cis rs10504073 0.584 rs1511365 chr8:49975321 A/T cg00325661 chr8:49890786 NA 0.34 7.76 0.39 9.97e-14 Blood metabolite ratios; LIHC cis rs11719291 0.584 rs13080725 chr3:49076092 G/A cg07636037 chr3:49044803 WDR6 -0.84 -8.52 -0.42 5.33e-16 Cognitive function; LIHC cis rs1816752 0.806 rs3816218 chr13:25017171 A/G cg22771759 chr13:24902376 NA 0.31 6.47 0.33 3.49e-10 Obesity-related traits; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC cis rs2806561 0.765 rs682766 chr1:23516397 C/G cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.45e-11 Height; LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg25204440 chr1:209979598 IRF6 0.51 8.04 0.4 1.48e-14 Cleft lip with or without cleft palate; LIHC cis rs7412746 0.621 rs11204749 chr1:150929563 G/A cg17724175 chr1:150552817 MCL1 0.39 7.59 0.38 3.05e-13 Melanoma; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg21724239 chr8:58056113 NA 0.57 7.62 0.38 2.58e-13 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11869233 chr2:48009809 MSH6 0.39 6.13 0.31 2.4e-9 Pancreatic cancer; LIHC cis rs4660306 0.884 rs7543076 chr1:45964238 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.64 -7.58 -0.38 3.2e-13 Homocysteine levels; LIHC cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg00343986 chr7:65444356 GUSB 0.44 6.13 0.31 2.49e-9 Aortic root size; LIHC cis rs477692 0.699 rs528549 chr10:131381574 A/G cg19680672 chr10:131412579 MGMT -0.4 -6.12 -0.31 2.56e-9 Response to temozolomide; LIHC cis rs1790761 0.692 rs638140 chr11:67333858 G/C cg01069141 chr11:67398826 TBX10;NUDT8 0.37 6.51 0.33 2.68e-10 Mean corpuscular volume; LIHC cis rs2050392 0.861 rs1042058 chr10:30728101 T/C cg25182066 chr10:30743637 MAP3K8 -0.48 -7.93 -0.39 3.23e-14 Inflammatory bowel disease; LIHC cis rs11098499 0.954 rs10017371 chr4:120293776 A/G cg09307838 chr4:120376055 NA 0.73 11.0 0.51 2.65e-24 Corneal astigmatism; LIHC cis rs17685 0.753 rs1637044 chr7:75703744 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2797160 1.000 rs1935774 chr6:125996661 A/G cg05901451 chr6:126070800 HEY2 0.43 7.59 0.38 3.07e-13 Endometrial cancer; LIHC cis rs1552244 0.882 rs7636817 chr3:10014876 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.93 0.47 1.43e-20 Alzheimer's disease; LIHC cis rs11888559 0.655 rs4673244 chr2:204043066 A/T cg24605529 chr2:203879461 NBEAL1 0.76 5.81 0.3 1.44e-8 Height; LIHC cis rs473651 0.837 rs563458 chr2:239345613 T/A cg18131467 chr2:239335373 ASB1 1.1 20.8 0.75 1.13e-62 Multiple system atrophy; LIHC cis rs9486719 0.843 rs2205754 chr6:96843134 T/C cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs1552244 0.882 rs17050699 chr3:10037167 G/A cg08888203 chr3:10149979 C3orf24 0.45 5.93 0.31 7.26e-9 Alzheimer's disease; LIHC cis rs6461049 0.800 rs3800913 chr7:2163237 A/G cg02951883 chr7:2050386 MAD1L1 -0.61 -9.77 -0.47 4.65e-20 Schizophrenia; LIHC cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg00149659 chr3:10157352 C3orf10 -0.62 -6.69 -0.34 8.97e-11 Alzheimer's disease; LIHC cis rs4819052 0.724 rs1304487 chr21:46657283 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.64 -10.02 -0.48 6.67e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs57590327 0.555 rs3755713 chr3:81811224 A/G cg07356753 chr3:81810745 GBE1 -0.55 -8.3 -0.41 2.44e-15 Extraversion; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12484756 chr19:10764617 ILF3;LOC147727 0.52 6.69 0.34 9.4e-11 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg05590025 chr7:65112418 INTS4L2 -0.59 -6.58 -0.34 1.81e-10 Diabetic kidney disease; LIHC cis rs7044106 0.762 rs7357638 chr9:123389204 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.66 0.38 1.95e-13 Hip circumference adjusted for BMI; LIHC cis rs9325144 0.647 rs7957185 chr12:38909710 G/A cg26384229 chr12:38710491 ALG10B -0.55 -7.42 -0.37 9.39e-13 Morning vs. evening chronotype; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20463403 chr6:36168142 BRPF3 0.44 6.42 0.33 4.53e-10 Longevity; LIHC cis rs589448 0.902 rs315113 chr12:69786543 G/T cg14784868 chr12:69753453 YEATS4 -0.96 -22.46 -0.77 2.73e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs3806843 0.676 rs778591 chr5:140025484 G/A cg16179182 chr5:140090404 VTRNA1-1 0.37 6.0 0.31 4.91e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs6973256 0.661 rs2550989 chr7:133500313 A/T cg03336402 chr7:133662267 EXOC4 -0.49 -6.68 -0.34 9.43e-11 Intelligence (multi-trait analysis); LIHC cis rs12602486 1.000 rs76913347 chr17:42267048 C/T cg08193365 chr17:42277699 NA 1.04 7.22 0.36 3.49e-12 Glycated hemoglobin levels; LIHC cis rs473651 0.935 rs578510 chr2:239343140 C/T cg18131467 chr2:239335373 ASB1 1.09 20.67 0.75 3.54e-62 Multiple system atrophy; LIHC trans rs11148252 0.557 rs9536223 chr13:53233194 A/T cg18335740 chr13:41363409 SLC25A15 0.58 10.49 0.49 1.7e-22 Lewy body disease; LIHC cis rs4742903 0.967 rs10125661 chr9:106868443 A/G cg14250997 chr9:106856677 SMC2 0.43 7.66 0.38 1.95e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6960043 0.738 rs12538043 chr7:15058998 C/G cg19272540 chr7:15055459 NA 0.25 6.5 0.33 2.81e-10 Type 2 diabetes; LIHC cis rs2250402 0.510 rs7535 chr15:40328575 G/C cg01081584 chr15:40268610 EIF2AK4 -0.52 -6.11 -0.31 2.67e-9 Corneal curvature; LIHC cis rs11098499 0.779 rs7356491 chr4:120381974 C/T cg09307838 chr4:120376055 NA 0.79 12.54 0.56 5.98e-30 Corneal astigmatism; LIHC cis rs8062405 0.823 rs7202948 chr16:28558289 T/A cg07451762 chr16:28383216 NA 0.33 6.84 0.35 3.74e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10489202 0.657 rs3767478 chr1:168069626 G/A cg24449463 chr1:168025552 DCAF6 -0.51 -6.87 -0.35 2.99e-11 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01717254 chr2:85843265 USP39 0.47 6.4 0.33 5.08e-10 Pancreatic cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21119375 chr2:44393385 NA -0.4 -6.17 -0.32 1.91e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1538970 0.962 rs2153608 chr1:45813941 C/T cg05343316 chr1:45956843 TESK2 -0.54 -8.13 -0.4 7.9e-15 Platelet count; LIHC cis rs208520 0.690 rs851459 chr6:66813989 A/G cg07460842 chr6:66804631 NA -0.86 -9.39 -0.45 8.54e-19 Exhaled nitric oxide output; LIHC cis rs1165668 0.816 rs1866069 chr12:104310545 G/T cg21863207 chr12:104234989 NT5DC3 -0.45 -7.68 -0.38 1.67e-13 Coronary heart disease (SNP X SNP interaction); LIHC cis rs10857712 0.904 rs7918164 chr10:135223323 G/A cg19623624 chr10:135278901 LOC619207 -0.42 -6.52 -0.33 2.55e-10 Systemic lupus erythematosus; LIHC trans rs7246657 0.943 rs10409204 chr19:37917692 G/A cg10208301 chr11:6592745 DNHD1 0.45 6.04 0.31 4.06e-9 Coronary artery calcification; LIHC cis rs7772486 0.790 rs2265472 chr6:146220758 G/C cg05347473 chr6:146136440 FBXO30 0.36 5.85 0.3 1.16e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1914816 0.941 rs2938691 chr15:76507206 G/A cg03037974 chr15:76606532 NA -0.6 -6.23 -0.32 1.4e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs3862030 0.720 rs7081110 chr10:104231651 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -7.26 -0.37 2.68e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs919433 0.679 rs7564924 chr2:198513877 C/T cg03934865 chr2:198174659 NA 0.44 6.63 0.34 1.3e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg25894440 chr7:65020034 NA -0.52 -6.0 -0.31 5.05e-9 Diabetic kidney disease; LIHC cis rs7572733 0.576 rs1368989 chr2:198937082 T/C cg03934865 chr2:198174659 NA 0.44 6.27 0.32 1.07e-9 Dermatomyositis; LIHC cis rs921968 0.541 rs3770216 chr2:219443717 A/G cg02176678 chr2:219576539 TTLL4 -0.56 -7.75 -0.39 1.03e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg23758822 chr17:41437982 NA 0.94 17.96 0.7 2.83e-51 Menopause (age at onset); LIHC cis rs2836974 0.563 rs6517522 chr21:40553845 T/C cg17971929 chr21:40555470 PSMG1 0.46 6.24 0.32 1.32e-9 Cognitive function; LIHC cis rs9322817 0.691 rs9486015 chr6:105254000 C/T cg02098413 chr6:105308735 HACE1 -0.42 -7.76 -0.39 9.72e-14 Thyroid stimulating hormone; LIHC cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg23978390 chr7:1156363 C7orf50 0.53 7.9 0.39 3.83e-14 Longevity;Endometriosis; LIHC cis rs4969178 0.600 rs4969183 chr17:76393372 A/G cg02836325 chr17:76403955 PGS1 0.33 6.53 0.33 2.42e-10 HDL cholesterol levels; LIHC cis rs7772486 0.790 rs6917482 chr6:146243581 C/T cg05347473 chr6:146136440 FBXO30 -0.37 -5.91 -0.3 8.14e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6815814 0.861 rs7658651 chr4:38786002 A/C cg06935464 chr4:38784597 TLR10 0.53 9.33 0.45 1.41e-18 Breast cancer; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg24846343 chr22:24311635 DDTL 0.72 14.22 0.61 2.23e-36 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11758351 1.000 rs80095925 chr6:26184942 C/T cg06951627 chr6:26196580 NA 0.54 5.92 0.3 7.89e-9 Gout;Renal underexcretion gout; LIHC cis rs3733585 0.773 rs13107466 chr4:10019390 G/A cg11266682 chr4:10021025 SLC2A9 0.33 7.15 0.36 5.29e-12 Cleft plate (environmental tobacco smoke interaction); LIHC cis rs523522 0.962 rs11065145 chr12:120947419 A/G cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.57 -10.55 -0.5 1.04e-22 Total body bone mineral density; LIHC cis rs4665809 0.549 rs72809635 chr2:26411674 G/A cg04944784 chr2:26401820 FAM59B 0.66 7.04 0.36 1.08e-11 Gut microbiome composition (summer); LIHC cis rs1113500 0.933 rs10881498 chr1:108634984 C/A cg06207961 chr1:108661230 NA 0.37 7.34 0.37 1.55e-12 Growth-regulated protein alpha levels; LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs4819052 0.851 rs9977178 chr21:46664531 G/T cg11663144 chr21:46675770 NA -0.33 -6.01 -0.31 4.82e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg05128992 chr18:3450160 TGIF1 -0.36 -6.5 -0.33 2.78e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6545883 0.826 rs2694651 chr2:61588642 T/C cg15711740 chr2:61764176 XPO1 0.42 5.84 0.3 1.18e-8 Tuberculosis; LIHC cis rs2303745 0.589 rs6512179 chr19:17399105 T/C cg10664184 chr19:17420304 DDA1 0.46 5.86 0.3 1.07e-8 Systemic lupus erythematosus; LIHC cis rs34172651 0.917 rs200536 chr16:24749203 G/A cg00152838 chr16:24741724 TNRC6A 0.45 5.93 0.31 7.58e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg09455208 chr3:40491958 NA 0.37 7.37 0.37 1.26e-12 Renal cell carcinoma; LIHC cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg06238570 chr21:40685208 BRWD1 0.62 7.58 0.38 3.3e-13 Cognitive function; LIHC trans rs11098499 0.954 rs6847248 chr4:120225955 A/G cg25214090 chr10:38739885 LOC399744 0.58 8.92 0.43 2.86e-17 Corneal astigmatism; LIHC cis rs727563 0.635 rs713988 chr22:42159072 A/G cg03806693 chr22:41940476 POLR3H 0.98 10.29 0.49 7.98e-22 Crohn's disease;Inflammatory bowel disease; LIHC trans rs877282 0.945 rs12776447 chr10:790625 A/G cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs7937890 0.631 rs7118886 chr11:14427517 T/C cg02886208 chr11:14281011 SPON1 -0.55 -7.78 -0.39 8.91e-14 Mitochondrial DNA levels; LIHC cis rs9612 1.000 rs12611034 chr19:44268678 C/T cg08581076 chr19:44259116 C19orf61 0.61 7.49 0.38 6.11e-13 Exhaled nitric oxide output; LIHC cis rs561341 0.609 rs2051810 chr17:30195841 C/T cg13647721 chr17:30228624 UTP6 -0.69 -7.11 -0.36 6.92e-12 Hip circumference adjusted for BMI; LIHC cis rs3749237 0.557 rs7631908 chr3:49425707 T/G cg03060546 chr3:49711283 APEH 0.58 9.54 0.46 2.7e-19 Resting heart rate; LIHC cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg20887711 chr4:1340912 KIAA1530 0.79 12.43 0.56 1.56e-29 Longevity; LIHC trans rs35110281 0.837 rs7279958 chr21:45016016 C/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.28 0.32 1.02e-9 Mean corpuscular volume; LIHC cis rs17711722 0.690 rs116823227 chr7:65331001 A/G cg18876405 chr7:65276391 NA 0.52 7.82 0.39 6.62e-14 Calcium levels; LIHC cis rs1997103 0.871 rs9649855 chr7:55410222 T/C cg17469321 chr7:55412551 NA 0.47 6.98 0.35 1.56e-11 QRS interval (sulfonylurea treatment interaction); LIHC trans rs4927850 0.958 rs2044599 chr3:195736740 G/A cg16724585 chr3:197361211 NA -0.47 -6.25 -0.32 1.21e-9 Pancreatic cancer; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg01516881 chr6:292596 DUSP22 -0.51 -6.55 -0.33 2.13e-10 Menopause (age at onset); LIHC trans rs1994135 0.617 rs10844642 chr12:33730368 A/C cg26384229 chr12:38710491 ALG10B 0.45 6.19 0.32 1.73e-9 Resting heart rate; LIHC cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg03517284 chr6:25882590 NA 0.39 5.93 0.31 7.59e-9 Height; LIHC trans rs875971 1.000 rs7783613 chr7:65805261 C/T cg10756647 chr7:56101905 PSPH -0.44 -6.35 -0.32 6.68e-10 Aortic root size; LIHC cis rs8038465 0.638 rs7495543 chr15:73955133 G/C cg15420318 chr15:73925796 NPTN 0.44 6.75 0.34 6.24e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs644799 0.544 rs499637 chr11:95569183 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.6 8.67 0.42 1.71e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3812111 0.774 rs563962 chr6:116431372 G/A cg08036074 chr6:116424633 NT5DC1 0.67 12.01 0.54 5.76e-28 Age-related macular degeneration; LIHC trans rs214034 0.825 rs2710655 chr2:17853822 T/C cg09061216 chr1:1558936 MIB2 0.53 6.24 0.32 1.29e-9 Response to amphetamines; LIHC cis rs6840360 0.509 rs62327273 chr4:152547594 A/G cg22705602 chr4:152727874 NA -0.34 -6.49 -0.33 3.08e-10 Intelligence (multi-trait analysis); LIHC cis rs4700695 0.698 rs416369 chr5:65231058 C/T cg21114390 chr5:65439923 SFRS12 0.49 6.55 0.33 2.15e-10 Facial morphology (factor 19); LIHC cis rs700651 0.789 rs6434949 chr2:198855510 T/A cg03934865 chr2:198174659 NA 0.46 6.61 0.34 1.44e-10 Intracranial aneurysm; LIHC cis rs6430585 0.583 rs2304370 chr2:136561735 G/A cg07305463 chr2:136567211 LCT -0.37 -5.97 -0.31 6.07e-9 Corneal structure; LIHC cis rs4423214 1.000 rs12793530 chr11:71161656 G/A cg24826892 chr11:71159390 DHCR7 0.52 6.69 0.34 9.16e-11 Vitamin D levels; LIHC cis rs7131987 0.903 rs7974221 chr12:29399448 A/G cg21522988 chr12:29376872 FAR2 0.3 6.99 0.35 1.48e-11 QT interval; LIHC cis rs2274273 0.840 rs6573014 chr14:55735892 C/T cg01864836 chr14:55583639 NA 0.38 6.94 0.35 1.94e-11 Protein biomarker; LIHC cis rs3789045 0.774 rs12041243 chr1:204490470 A/G cg17419461 chr1:204415978 PIK3C2B -0.43 -6.55 -0.33 2.15e-10 Educational attainment (college completion); LIHC cis rs3740540 0.507 rs2362500 chr10:126290431 T/C cg04949429 chr10:126290192 LHPP 0.46 7.5 0.38 5.65e-13 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs10791097 0.667 rs4937585 chr11:130741940 A/G cg14779329 chr11:130786720 SNX19 0.4 6.04 0.31 4.02e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs2096176 0.632 rs1339814 chr10:26312824 C/T cg01396774 chr2:218299024 DIRC3 -0.31 -6.16 -0.32 2.06e-9 Obesity-related traits; LIHC cis rs17253792 0.822 rs75555677 chr14:56096429 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -11.92 -0.54 1.19e-27 Alzheimer's disease; LIHC cis rs12497850 0.805 rs11130176 chr3:48844077 A/G cg07636037 chr3:49044803 WDR6 0.93 16.94 0.68 3.74e-47 Parkinson's disease; LIHC cis rs1400745 0.756 rs10136352 chr14:35334555 C/T cg05294307 chr14:35346193 BAZ1A -0.46 -7.94 -0.39 2.96e-14 Monocyte count; LIHC cis rs629922 0.671 rs513039 chr11:114037158 G/A cg01914181 chr11:114070210 ZBTB16 0.43 6.06 0.31 3.53e-9 Paneth cell defects in Crohn's disease; LIHC cis rs992157 0.835 rs2045434 chr2:219144498 A/G cg00012203 chr2:219082015 ARPC2 -0.82 -13.08 -0.58 5.58e-32 Colorectal cancer; LIHC cis rs17685 0.753 rs1637044 chr7:75703744 T/C cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs427394 0.582 rs274662 chr5:6704860 G/A cg10857441 chr5:6722123 POLS -0.37 -6.27 -0.32 1.09e-9 Menopause (age at onset); LIHC cis rs8005677 1.000 rs4982709 chr14:23394699 C/T cg25600027 chr14:23388339 RBM23 -0.41 -5.95 -0.31 6.63e-9 Cognitive ability (multi-trait analysis); LIHC cis rs507080 0.736 rs658676 chr11:118571123 C/T cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs875971 1.000 rs1544549 chr7:66090663 T/A cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.31e-10 Aortic root size; LIHC cis rs1387259 0.758 rs2634670 chr12:48771877 G/A cg21466736 chr12:48725269 NA -0.62 -9.16 -0.44 4.73e-18 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs72843506 0.586 rs59890010 chr17:19863673 C/T cg12065943 chr17:19881925 AKAP10 -0.38 -6.4 -0.33 5.06e-10 Schizophrenia; LIHC cis rs12479064 0.724 rs6748200 chr2:100080895 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.49 -6.87 -0.35 3.09e-11 Chronic sinus infection; LIHC cis rs17270561 0.525 rs10484432 chr6:26008876 G/A cg16482183 chr6:26056742 HIST1H1C 0.85 11.15 0.52 7.77e-25 Iron status biomarkers; LIHC cis rs4555082 1.000 rs7149013 chr14:105759840 T/C cg06808227 chr14:105710500 BRF1 -0.54 -6.8 -0.35 4.54e-11 Mean platelet volume;Platelet distribution width; LIHC trans rs1499614 1.000 rs60326618 chr7:66166358 G/A cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs12594515 1.000 rs8043291 chr15:45996247 T/A cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs933688 1.000 rs12651840 chr5:90729592 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.26 0.68 1.78e-48 Smoking behavior; LIHC cis rs9916302 0.904 rs12452880 chr17:37591149 G/C cg00129232 chr17:37814104 STARD3 -0.41 -6.5 -0.33 2.9e-10 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.77 0.8 2.76e-78 Prudent dietary pattern; LIHC cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg09222892 chr1:25734099 RHCE -0.46 -8.36 -0.41 1.57e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs2404602 0.735 rs4886805 chr15:76739384 A/G cg23625390 chr15:77176239 SCAPER 0.49 8.16 0.4 6.57e-15 Blood metabolite levels; LIHC cis rs3806843 0.657 rs2563283 chr5:140105978 C/A cg19875535 chr5:140030758 IK -0.4 -6.58 -0.34 1.78e-10 Depressive symptoms (multi-trait analysis); LIHC trans rs116095464 0.558 rs10077076 chr5:231940 C/T cg00938859 chr5:1591904 SDHAP3 0.59 7.19 0.36 4.19e-12 Breast cancer; LIHC cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -11.92 -0.54 1.19e-27 Alzheimer's disease; LIHC cis rs611744 0.967 rs662591 chr8:109211358 C/T cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs4746818 0.901 rs7914719 chr10:70903832 T/C cg11621586 chr10:70884670 VPS26A 0.87 14.21 0.61 2.47e-36 Left atrial antero-posterior diameter; LIHC cis rs1552244 0.706 rs279545 chr3:9972493 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.54 7.6 0.38 2.8e-13 Alzheimer's disease; LIHC cis rs965469 0.948 rs6051769 chr20:3326438 G/A cg25506879 chr20:3388711 C20orf194 -0.58 -6.6 -0.34 1.6e-10 IFN-related cytopenia; LIHC cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg08280861 chr8:58055591 NA 0.5 5.96 0.31 6.25e-9 Developmental language disorder (linguistic errors); LIHC trans rs941408 1.000 rs1736176 chr19:2790394 G/A cg19676328 chr12:49525230 TUBA1B -0.38 -6.13 -0.31 2.4e-9 Total cholesterol levels; LIHC cis rs11971779 0.648 rs28754644 chr7:139065057 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg06453172 chr10:134556979 INPP5A -0.62 -8.38 -0.41 1.38e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs9641123 0.639 rs2190333 chr7:93245171 A/G cg09745688 chr16:2908918 PRSS22 -0.36 -6.34 -0.32 7.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs7487075 0.780 rs2279559 chr12:46767175 A/C cg11331445 chr12:47219877 SLC38A4 0.29 5.93 0.31 7.49e-9 Itch intensity from mosquito bite; LIHC cis rs17685 0.672 rs1639623 chr7:75707951 A/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.65 -0.38 2.13e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9733 0.570 rs951281 chr1:150691122 A/C cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC trans rs875971 1.000 rs3735148 chr7:65971009 T/G cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.15e-10 Aortic root size; LIHC cis rs1707322 1.000 rs785469 chr1:46521091 C/T cg03146154 chr1:46216737 IPP -0.44 -7.16 -0.36 4.84e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17253792 0.822 rs75897560 chr14:56090965 C/T cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs9309473 0.950 rs13408433 chr2:73883072 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.25 -0.32 1.23e-9 Metabolite levels; LIHC cis rs2354432 0.607 rs2353999 chr1:146830686 T/C cg25205988 chr1:146714368 CHD1L -0.83 -9.47 -0.46 4.76e-19 Mitochondrial DNA levels; LIHC cis rs8010715 0.816 rs11574503 chr14:24601318 C/G cg23112188 chr14:24563095 PCK2 0.29 6.09 0.31 3.07e-9 IgG glycosylation; LIHC cis rs428668 0.681 rs430961 chr5:150700559 C/G cg11125805 chr5:150678162 SLC36A3 0.4 8.1 0.4 9.92e-15 Skin aging (microtopography measurement); LIHC cis rs2836974 0.544 rs8128919 chr21:40711862 C/T cg11890956 chr21:40555474 PSMG1 0.57 8.54 0.42 4.39e-16 Cognitive function; LIHC cis rs875971 1.000 rs2077593 chr7:65892530 A/G cg11764359 chr7:65958608 NA 0.88 15.9 0.65 5.13e-43 Aortic root size; LIHC cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg11645453 chr3:52864694 ITIH4 0.22 5.77 0.3 1.75e-8 Bipolar disorder; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02169333 chr16:57023494 NLRC5 0.43 6.17 0.32 1.95e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg09367891 chr1:107599246 PRMT6 0.72 12.05 0.55 4.09e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6545883 0.894 rs12620105 chr2:61512321 A/T cg14146966 chr2:61757674 XPO1 -0.43 -7.31 -0.37 1.93e-12 Tuberculosis; LIHC cis rs1215050 0.904 rs890469 chr4:98923293 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -6.04 -0.31 4.09e-9 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs72766638 0.848 rs11789898 chr9:136925663 A/C cg09836344 chr4:1243392 C4orf42;CTBP1 0.51 6.46 0.33 3.53e-10 Mosquito bite size; LIHC cis rs5769765 0.542 rs5770725 chr22:50256309 C/T cg09182678 chr22:50328711 NA 0.47 6.0 0.31 5.14e-9 Schizophrenia; LIHC cis rs11626933 1.000 rs3742669 chr14:90767746 C/A cg07150772 chr14:90864620 CALM1 0.4 5.72 0.3 2.36e-8 Gut microbiota (bacterial taxa); LIHC cis rs12701220 0.604 rs34904312 chr7:1135883 G/A cg09177884 chr7:1199841 ZFAND2A -0.53 -6.2 -0.32 1.67e-9 Bronchopulmonary dysplasia; LIHC cis rs2380220 0.516 rs7748108 chr6:96008082 T/C cg04719120 chr6:96025338 MANEA 0.53 6.9 0.35 2.49e-11 Behavioural disinhibition (generation interaction); LIHC cis rs523522 0.962 rs4766966 chr12:120942911 G/C cg12219531 chr12:120966889 COQ5 0.66 13.19 0.58 2.06e-32 High light scatter reticulocyte count; LIHC cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg11764359 chr7:65958608 NA 0.68 9.31 0.45 1.58e-18 Aortic root size; LIHC trans rs208520 0.661 rs7747492 chr6:66857788 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.47 -0.42 7.47e-16 Exhaled nitric oxide output; LIHC cis rs3806843 0.735 rs801185 chr5:140068869 A/G cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06426011 chr16:12798592 CPPED1 0.57 6.93 0.35 2.05e-11 Systolic blood pressure; LIHC cis rs727505 0.954 rs59673207 chr7:124596982 G/C cg23710748 chr7:124431027 NA -0.32 -5.76 -0.3 1.87e-8 Lewy body disease; LIHC cis rs6430585 0.528 rs16832205 chr2:136684632 G/A cg07305463 chr2:136567211 LCT -0.39 -5.98 -0.31 5.48e-9 Corneal structure; LIHC cis rs116095464 0.558 rs10075018 chr5:239175 G/A cg22496380 chr5:211416 CCDC127 -1.04 -10.71 -0.5 2.87e-23 Breast cancer; LIHC cis rs6973256 0.543 rs13243553 chr7:133506955 A/G cg10665199 chr7:133106180 EXOC4 -0.34 -5.86 -0.3 1.11e-8 Intelligence (multi-trait analysis); LIHC trans rs9929218 0.508 rs1559366 chr16:68799611 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.79 15.9 0.65 5.24e-43 Colorectal cancer; LIHC cis rs7945705 0.837 rs2742474 chr11:9002089 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.43 -7.24 -0.36 2.94e-12 Hemoglobin concentration; LIHC cis rs7927771 1.000 rs11039255 chr11:47495746 G/T cg18512352 chr11:47633146 NA -0.26 -6.1 -0.31 2.87e-9 Subjective well-being; LIHC cis rs4975616 0.804 rs456366 chr5:1337070 T/C cg26373071 chr5:1325741 CLPTM1L 0.36 5.8 0.3 1.49e-8 Lung cancer; LIHC trans rs1814175 0.645 rs28447324 chr11:50046629 C/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs875971 0.862 rs1983372 chr7:65611351 C/T cg18252515 chr7:66147081 NA 0.43 5.98 0.31 5.68e-9 Aortic root size; LIHC cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg12463550 chr7:65579703 CRCP 0.68 7.05 0.36 9.9e-12 Diabetic kidney disease; LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs8028182 0.583 rs4886722 chr15:75921636 C/A cg20655648 chr15:75932815 IMP3 0.46 6.52 0.33 2.53e-10 Sudden cardiac arrest; LIHC cis rs1577917 0.958 rs12199832 chr6:86652748 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.29 -0.49 8.14e-22 Response to antipsychotic treatment; LIHC cis rs919433 0.680 rs12621129 chr2:198265350 T/C cg03934865 chr2:198174659 NA -0.54 -8.16 -0.4 6.53e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7296418 0.961 rs10773921 chr12:123541606 C/T cg00376283 chr12:123451042 ABCB9 0.75 13.57 0.59 7.33e-34 Platelet count; LIHC cis rs11577318 0.853 rs11803933 chr1:26629465 G/C cg10402321 chr1:26617780 UBXN11 -0.38 -5.8 -0.3 1.48e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg21747090 chr2:27597821 SNX17 -0.46 -6.96 -0.35 1.73e-11 Total body bone mineral density; LIHC cis rs2404602 0.735 rs11632222 chr15:76712927 C/G cg03037974 chr15:76606532 NA -0.64 -11.12 -0.52 9.9e-25 Blood metabolite levels; LIHC cis rs17152411 1.000 rs11245432 chr10:126616861 G/A cg07906193 chr10:126599966 NA 0.47 7.32 0.37 1.76e-12 Height; LIHC cis rs2235642 0.653 rs7197288 chr16:1654753 C/A cg03034668 chr16:1723424 CRAMP1L -0.38 -6.71 -0.34 8.27e-11 Coronary artery disease; LIHC trans rs11148252 0.967 rs11620062 chr13:52994026 T/G cg18335740 chr13:41363409 SLC25A15 0.35 6.29 0.32 9.44e-10 Lewy body disease; LIHC cis rs2153535 0.580 rs4451187 chr6:8473910 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.15e-16 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20682991 chr2:74981952 NA 0.34 6.17 0.32 1.98e-9 Pancreatic cancer; LIHC cis rs9811920 0.609 rs9817005 chr3:99682692 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.15 0.36 5.37e-12 Axial length; LIHC cis rs910316 0.763 rs2080201 chr14:75629972 C/T cg08847533 chr14:75593920 NEK9 -0.86 -17.04 -0.68 1.4e-47 Height; LIHC cis rs651907 0.514 rs11706494 chr3:101509475 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs72480748 0.509 rs3865457 chr19:41398969 C/T cg04176888 chr19:41596066 CYP2A13 0.36 6.07 0.31 3.31e-9 Post bronchodilator FEV1;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05596267 chr15:34331198 CHRM5;AVEN -0.43 -6.28 -0.32 1.06e-9 Systolic blood pressure; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08168689 chr14:76455272 C14orf179 0.47 6.14 0.32 2.31e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2152924 0.539 rs1765756 chr1:110007652 G/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -6.68 -0.34 9.9e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs2272990 0.558 rs6907943 chr6:3078266 A/C cg22816218 chr6:3091462 RIPK1 -0.56 -6.48 -0.33 3.24e-10 Preschool internalizing problems; LIHC cis rs8044868 0.530 rs2550870 chr16:72070129 C/T cg01557791 chr16:72042693 DHODH -0.4 -6.59 -0.34 1.69e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs9393692 0.645 rs766406 chr6:26319588 G/T cg13736514 chr6:26305472 NA -0.42 -6.62 -0.34 1.4e-10 Educational attainment; LIHC cis rs1552244 0.554 rs13079240 chr3:10047246 C/T cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs11122272 0.735 rs2808592 chr1:231523757 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs17818399 0.926 rs1378764 chr2:46839681 C/T cg02822958 chr2:46747628 ATP6V1E2 0.45 6.68 0.34 9.75e-11 Height; LIHC cis rs875971 0.545 rs6460276 chr7:65647277 G/A cg11764359 chr7:65958608 NA 0.51 7.06 0.36 9.43e-12 Aortic root size; LIHC cis rs9419702 0.568 rs7093241 chr10:133556596 G/A cg20568497 chr10:133558893 NA 0.43 6.63 0.34 1.29e-10 Survival in rectal cancer; LIHC cis rs8083850 0.748 rs11661696 chr18:50755536 C/T cg24270629 chr18:50823537 DCC -0.48 -6.93 -0.35 2.06e-11 Intelligence (multi-trait analysis); LIHC cis rs875971 0.862 rs6964437 chr7:65686444 A/G cg11764359 chr7:65958608 NA -0.75 -12.45 -0.56 1.34e-29 Aortic root size; LIHC cis rs2075371 0.965 rs1862049 chr7:133978344 A/T cg20476274 chr7:133979776 SLC35B4 0.76 12.92 0.57 2.22e-31 Mean platelet volume; LIHC cis rs9660180 0.620 rs3817856 chr1:1663831 C/T cg23982607 chr1:1823379 GNB1 0.49 7.09 0.36 7.69e-12 Body mass index; LIHC cis rs10540 1.000 rs61877775 chr11:521462 C/T cg03576123 chr11:487126 PTDSS2 -1.25 -8.51 -0.42 5.45e-16 Body mass index; LIHC cis rs2066819 1.000 rs808919 chr12:56647911 C/G cg26714650 chr12:56694279 CS 1.06 12.41 0.56 1.86e-29 Psoriasis vulgaris; LIHC cis rs875971 1.000 rs6970030 chr7:65968679 T/C cg11764359 chr7:65958608 NA 0.91 16.89 0.67 5.59e-47 Aortic root size; LIHC cis rs17685 0.712 rs6954569 chr7:75738885 T/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.21 -0.32 1.52e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs45544231 0.569 rs1362546 chr16:52549935 C/T cg09051775 chr16:52580266 TOX3 -0.31 -5.73 -0.3 2.19e-8 Restless legs syndrome; LIHC cis rs1419980 0.673 rs10772553 chr12:7768089 G/A cg10578777 chr12:7781093 NA -0.46 -8.26 -0.41 3.21e-15 HDL cholesterol levels; LIHC trans rs208520 0.955 rs208532 chr6:66961280 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.69 -0.34 9.29e-11 Exhaled nitric oxide output; LIHC cis rs3806843 0.966 rs10036519 chr5:140151701 C/T cg26395211 chr5:140044315 WDR55 0.41 6.08 0.31 3.16e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs3862030 0.720 rs11191295 chr10:104231054 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.27 -0.37 2.42e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs7903847 0.620 rs2297988 chr10:99118382 A/G cg20016023 chr10:99160130 RRP12 -0.4 -6.11 -0.31 2.68e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs3008870 0.755 rs2755251 chr1:67496425 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.66 11.27 0.52 2.9e-25 Lymphocyte percentage of white cells; LIHC cis rs2228479 0.850 rs17226498 chr16:89840631 T/C cg19635926 chr16:89946313 TCF25 0.5 6.48 0.33 3.24e-10 Skin colour saturation; LIHC cis rs3849570 0.555 rs4481177 chr3:81996817 A/T cg07356753 chr3:81810745 GBE1 0.43 6.85 0.35 3.42e-11 Waist circumference;Body mass index; LIHC trans rs6500602 0.767 rs8060219 chr16:4480158 T/A cg05791018 chr13:19965014 NA -0.28 -6.29 -0.32 9.62e-10 Schizophrenia; LIHC cis rs9916302 0.904 rs9892055 chr17:37510402 C/T cg07936489 chr17:37558343 FBXL20 0.83 13.53 0.59 1.02e-33 Glomerular filtration rate (creatinine); LIHC cis rs5769765 0.955 rs5769767 chr22:50276909 G/A cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC trans rs1005277 0.540 rs1987431 chr10:37988887 T/C cg27523141 chr10:43048294 ZNF37B 0.37 6.51 0.33 2.74e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg18357526 chr6:26021779 HIST1H4A -0.87 -12.34 -0.55 3.58e-29 Intelligence (multi-trait analysis); LIHC cis rs6461049 0.638 rs3778994 chr7:2175855 G/T cg14004847 chr7:1930337 MAD1L1 -0.39 -5.86 -0.3 1.09e-8 Schizophrenia; LIHC cis rs929354 1.000 rs1182384 chr7:157040642 A/G cg17757837 chr7:157058334 UBE3C -0.81 -14.44 -0.62 3.14e-37 Body mass index; LIHC cis rs6502050 0.835 rs4789676 chr17:80123078 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs597539 0.652 rs668576 chr11:68668208 A/G cg04772025 chr11:68637568 NA 0.46 6.04 0.31 4.05e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs244293 0.665 rs6504947 chr17:53004144 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.45 -6.56 -0.33 2.03e-10 Menarche (age at onset); LIHC cis rs7727544 0.709 rs272852 chr5:131688767 G/A cg24060327 chr5:131705240 SLC22A5 -0.57 -8.27 -0.41 2.98e-15 Blood metabolite levels; LIHC cis rs10504073 0.584 rs7820270 chr8:49971395 G/T cg00325661 chr8:49890786 NA 0.33 7.64 0.38 2.18e-13 Blood metabolite ratios; LIHC cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg12310025 chr6:25882481 NA 0.62 8.98 0.44 1.89e-17 Blood metabolite levels; LIHC cis rs6570726 0.935 rs12663204 chr6:145818373 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.77 0.47 4.63e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6964587 0.743 rs33993294 chr7:91998655 A/C cg17063962 chr7:91808500 NA 0.97 16.32 0.66 1.07e-44 Breast cancer; LIHC trans rs853679 0.769 rs17720293 chr6:28214698 C/T cg06606381 chr12:133084897 FBRSL1 -1.08 -7.03 -0.36 1.14e-11 Depression; LIHC cis rs634534 0.622 rs552130 chr11:65732800 T/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.45 6.98 0.35 1.56e-11 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs61931739 0.500 rs11053201 chr12:34453903 T/A cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg16262614 chr3:133464971 TF 0.28 6.21 0.32 1.51e-9 Iron status biomarkers; LIHC cis rs10927875 0.550 rs12121918 chr1:16183556 C/A cg21385522 chr1:16154831 NA -1.06 -11.77 -0.54 4.58e-27 Dilated cardiomyopathy; LIHC cis rs12477438 0.520 rs13798 chr2:99813614 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.05 0.63 1.26e-39 Chronic sinus infection; LIHC cis rs7582180 0.591 rs12991577 chr2:101010867 C/A cg14675211 chr2:100938903 LONRF2 0.54 8.25 0.41 3.54e-15 Intelligence (multi-trait analysis); LIHC cis rs919433 0.679 rs6757632 chr2:198530266 C/T cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02132458 chr4:57333267 SRP72 0.5 7.29 0.37 2.18e-12 Cognitive function; LIHC cis rs67311347 1.000 rs7617989 chr3:40512463 A/G cg00656387 chr3:40428638 ENTPD3 -0.45 -7.6 -0.38 2.92e-13 Renal cell carcinoma; LIHC trans rs7618501 0.633 rs6446193 chr3:50059758 T/C cg21659725 chr3:3221576 CRBN -0.67 -10.93 -0.51 4.69e-24 Intelligence (multi-trait analysis); LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg14893161 chr1:205819251 PM20D1 0.71 9.85 0.47 2.63e-20 Menarche (age at onset); LIHC trans rs11098499 0.865 rs10213221 chr4:120255926 G/A cg25214090 chr10:38739885 LOC399744 0.51 8.17 0.4 6.15e-15 Corneal astigmatism; LIHC cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg03806693 chr22:41940476 POLR3H 1.08 13.05 0.58 7.11e-32 Vitiligo; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00648153 chr6:74364149 SLC17A5 0.47 7.21 0.36 3.59e-12 Cognitive function; LIHC cis rs9733 0.596 rs2275236 chr1:150669952 A/G cg18016565 chr1:150552671 MCL1 -0.59 -11.48 -0.53 4.87e-26 Tonsillectomy; LIHC cis rs17102423 0.826 rs17825846 chr14:65598752 C/G cg11161011 chr14:65562177 MAX -0.49 -6.82 -0.35 4.24e-11 Obesity-related traits; LIHC cis rs6163 0.588 rs11191392 chr10:104526951 C/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.47 -6.86 -0.35 3.32e-11 Waist circumference;Hip circumference; LIHC cis rs2304069 0.909 rs30831 chr5:149359053 C/T cg12661370 chr5:149340060 SLC26A2 -0.56 -6.77 -0.34 5.6e-11 HIV-1 control; LIHC cis rs595982 0.559 rs117227130 chr19:49367959 A/G cg21252483 chr19:49399788 TULP2 -0.92 -10.22 -0.48 1.4e-21 Red cell distribution width; LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg06420487 chr17:61919686 SMARCD2 0.42 5.78 0.3 1.69e-8 Height; LIHC cis rs4407350 0.756 rs3827401 chr22:44890618 A/G cg26276947 chr22:44892394 LDOC1L 0.34 6.43 0.33 4.24e-10 Intelligence (multi-trait analysis); LIHC cis rs7027203 0.828 rs3957506 chr9:96588133 C/T cg14598338 chr9:96623480 NA -0.32 -6.26 -0.32 1.16e-9 DNA methylation (variation); LIHC cis rs1538970 0.816 rs868351 chr1:46009818 G/T cg24296786 chr1:45957014 TESK2 -0.46 -6.2 -0.32 1.59e-9 Platelet count; LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 25.06 0.8 2.11e-79 Prudent dietary pattern; LIHC trans rs1347297 0.756 rs10173183 chr2:179276427 C/T cg14011486 chr1:26737247 LIN28 0.45 6.92 0.35 2.22e-11 Alzheimer disease and age of onset; LIHC cis rs3812111 0.677 rs1204787 chr6:116535380 C/G cg08036074 chr6:116424633 NT5DC1 -0.38 -6.26 -0.32 1.18e-9 Age-related macular degeneration; LIHC cis rs5769765 0.908 rs7410318 chr22:50317049 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.28 -0.45 1.99e-18 Schizophrenia; LIHC cis rs79387448 0.745 rs1523197 chr2:103163732 A/G cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs17106184 1.000 rs12076849 chr1:51362441 C/T cg07174182 chr1:51127561 FAF1 -0.75 -8.1 -0.4 1.01e-14 Type 2 diabetes; LIHC trans rs17685 0.725 rs1044483 chr7:75659815 T/C cg19862616 chr7:65841803 NCRNA00174 -0.9 -18.35 -0.7 7.53e-53 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12444684 chr1:65431340 JAK1 0.42 6.09 0.31 3e-9 Lung function (FEV1/FVC); LIHC cis rs8114671 0.836 rs13042358 chr20:33634479 G/A cg07148914 chr20:33460835 GGT7 -0.55 -8.43 -0.41 9.93e-16 Height; LIHC cis rs79149102 0.579 rs12593476 chr15:75282092 A/C cg17294928 chr15:75287854 SCAMP5 -0.51 -6.44 -0.33 3.97e-10 Lung cancer; LIHC cis rs1577917 0.655 rs9444351 chr6:86247799 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.45 0.42 8.29e-16 Response to antipsychotic treatment; LIHC cis rs7771547 0.508 rs1570368 chr6:36437136 C/G cg07856975 chr6:36356162 ETV7 0.34 5.79 0.3 1.6e-8 Platelet distribution width; LIHC cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.16 -0.36 5.11e-12 Diabetic kidney disease; LIHC cis rs6752107 1.000 rs13391356 chr2:234170369 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.56 8.59 0.42 3.08e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs5769765 0.955 rs2319465 chr22:50265784 A/C cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs801193 0.660 rs2659914 chr7:66156914 C/T cg18876405 chr7:65276391 NA 0.34 6.27 0.32 1.06e-9 Aortic root size; LIHC cis rs2439831 0.850 rs28578398 chr15:44075046 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.5 0.42 6.09e-16 Lung cancer in ever smokers; LIHC trans rs1005277 0.540 rs116205409 chr10:38478970 G/A cg27523141 chr10:43048294 ZNF37B 0.38 6.34 0.32 7.24e-10 Extrinsic epigenetic age acceleration; LIHC cis rs11628318 0.614 rs12590775 chr14:103150623 A/G cg12046867 chr14:103022105 NA 0.43 6.67 0.34 1.02e-10 Platelet count; LIHC cis rs4819052 0.679 rs8132135 chr21:46694782 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 10.24 0.48 1.25e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6424115 0.931 rs2982390 chr1:24147830 G/C cg15997130 chr1:24165203 NA 0.46 9.29 0.45 1.81e-18 Immature fraction of reticulocytes; LIHC cis rs11958404 0.932 rs72816542 chr5:157416402 C/T cg05962755 chr5:157440814 NA 1.05 11.06 0.51 1.64e-24 IgG glycosylation; LIHC cis rs2197308 0.765 rs12824529 chr12:37931656 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs1348850 0.526 rs59972556 chr2:178399561 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.67 5.77 0.3 1.81e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg15691649 chr6:25882328 NA -0.44 -6.98 -0.35 1.58e-11 Height; LIHC cis rs1055129 0.516 rs7218498 chr17:73931847 C/G cg08125733 chr17:73851984 WBP2 0.56 8.7 0.43 1.46e-16 White matter hyperintensity burden; LIHC cis rs6138458 1.000 rs7269416 chr20:24976196 T/G cg26195577 chr20:24973756 C20orf3 1.2 16.23 0.66 2.61e-44 Blood protein levels; LIHC cis rs7552167 1.000 rs7552167 chr1:24518643 A/G cg01960748 chr1:24522592 NA -0.75 -10.18 -0.48 1.98e-21 Psoriasis vulgaris; LIHC cis rs9911578 1.000 rs8067571 chr17:56868856 C/T cg05425664 chr17:57184151 TRIM37 -0.58 -8.69 -0.43 1.55e-16 Intelligence (multi-trait analysis); LIHC cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg03060546 chr3:49711283 APEH 0.38 5.73 0.3 2.16e-8 Menarche (age at onset); LIHC cis rs35110281 0.667 rs4819286 chr21:45120121 G/A cg04455712 chr21:45112962 RRP1B 0.48 8.54 0.42 4.44e-16 Mean corpuscular volume; LIHC trans rs4843747 0.636 rs11864872 chr16:88105966 A/G cg09572067 chr16:29127029 RRN3P2 0.5 8.0 0.4 1.94e-14 Menopause (age at onset); LIHC cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg14393609 chr7:65229607 NA -0.43 -6.4 -0.33 5.1e-10 Calcium levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13319049 chr4:39699555 UBE2K -0.5 -6.06 -0.31 3.57e-9 Systolic blood pressure; LIHC cis rs700651 0.789 rs1976772 chr2:198868201 G/T cg00792783 chr2:198669748 PLCL1 0.42 6.03 0.31 4.36e-9 Intracranial aneurysm; LIHC cis rs4478037 0.749 rs9681623 chr3:33131375 G/T cg16652328 chr3:33138982 GLB1;TMPPE -0.6 -8.24 -0.41 3.73e-15 Major depressive disorder; LIHC cis rs7917772 0.619 rs2801050 chr10:104509393 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.56 6.51 0.33 2.72e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg17971929 chr21:40555470 PSMG1 -0.83 -9.66 -0.46 1.15e-19 Cognitive function; LIHC trans rs561341 0.681 rs56064462 chr17:30235116 G/A cg20587970 chr11:113659929 NA -0.56 -7.15 -0.36 5.39e-12 Hip circumference adjusted for BMI; LIHC cis rs12477438 0.501 rs11685756 chr2:99766215 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.55 0.64 1.25e-41 Chronic sinus infection; LIHC cis rs6951245 0.872 rs75280240 chr7:1058511 C/T cg24642844 chr7:1081250 C7orf50 -0.87 -8.76 -0.43 8.93e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3812111 0.676 rs9488853 chr6:116477518 C/T cg08036074 chr6:116424633 NT5DC1 -0.49 -8.22 -0.41 4.26e-15 Age-related macular degeneration; LIHC cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg00656387 chr3:40428638 ENTPD3 0.46 7.41 0.37 9.89e-13 Renal cell carcinoma; LIHC cis rs6088580 0.524 rs7274854 chr20:33228672 A/C cg07148914 chr20:33460835 GGT7 0.48 6.97 0.35 1.62e-11 Glomerular filtration rate (creatinine); LIHC cis rs9354352 0.967 rs6455062 chr6:66694131 T/A cg07460842 chr6:66804631 NA 0.59 9.47 0.46 4.88e-19 Initial pursuit acceleration in psychotic disorders; LIHC cis rs4595586 0.545 rs17546375 chr12:39407248 C/A cg26384229 chr12:38710491 ALG10B 0.48 5.76 0.3 1.84e-8 Morning vs. evening chronotype; LIHC cis rs208515 0.560 rs207084 chr6:66776966 T/C cg07460842 chr6:66804631 NA -0.96 -17.56 -0.69 1.19e-49 Exhaled nitric oxide levels; LIHC cis rs2204008 0.774 rs11180977 chr12:38263094 G/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs870825 0.616 rs7660939 chr4:185640792 T/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs921968 0.509 rs72963905 chr2:219547027 T/G cg02176678 chr2:219576539 TTLL4 -0.54 -7.07 -0.36 9.05e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs17125944 0.505 rs77433996 chr14:53212263 G/A cg00686598 chr14:53173677 PSMC6 1.23 15.76 0.65 1.95e-42 Alzheimer's disease (late onset); LIHC cis rs7098414 0.511 rs4934126 chr10:82151598 A/G cg01528321 chr10:82214614 TSPAN14 0.43 6.51 0.33 2.67e-10 Post bronchodilator FEV1; LIHC cis rs74233809 1.000 rs3781285 chr10:104825665 C/G cg03493300 chr10:104813866 CNNM2 0.47 6.15 0.32 2.18e-9 Birth weight; LIHC cis rs651907 0.557 rs11914318 chr3:101453858 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.4 0.49 3.31e-22 Colorectal cancer; LIHC cis rs9790314 1.000 rs464766 chr3:161087592 C/G cg03342759 chr3:160939853 NMD3 -0.67 -7.93 -0.39 3.05e-14 Morning vs. evening chronotype; LIHC cis rs2404602 0.611 rs2404734 chr15:76936165 T/C cg03037974 chr15:76606532 NA -0.6 -9.92 -0.47 1.49e-20 Blood metabolite levels; LIHC cis rs881375 0.678 rs4836834 chr9:123665901 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.64 0.34 1.2e-10 Rheumatoid arthritis; LIHC cis rs8027181 0.839 rs8024986 chr15:73024868 A/G cg25996835 chr15:72978165 BBS4;HIGD2B -0.53 -8.25 -0.41 3.57e-15 Triglyceride levels; LIHC cis rs6973256 0.605 rs7808879 chr7:133345471 A/T cg10665199 chr7:133106180 EXOC4 0.34 5.85 0.3 1.16e-8 Intelligence (multi-trait analysis); LIHC cis rs4803468 1.000 rs10413735 chr19:41921071 C/T cg09537434 chr19:41945824 ATP5SL -1.03 -21.78 -0.76 1.34e-66 Height; LIHC cis rs79387448 0.745 rs17027421 chr2:103159882 A/G cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs929354 0.651 rs6951298 chr7:156949149 T/C cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs736408 0.522 rs998909 chr3:52805093 A/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.17 -0.44 4.52e-18 Bipolar disorder; LIHC cis rs11098499 0.605 rs6833140 chr4:120266822 G/A cg09307838 chr4:120376055 NA 0.63 9.84 0.47 2.82e-20 Corneal astigmatism; LIHC cis rs921968 0.565 rs1541777 chr2:219587291 A/G cg02985541 chr2:219472218 PLCD4 -0.38 -6.66 -0.34 1.07e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2439831 0.614 rs2467733 chr15:43693328 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.88 15.73 0.65 2.44e-42 Lung cancer in ever smokers; LIHC cis rs11671005 0.695 rs11673069 chr19:58934918 C/G cg25952890 chr19:58913133 NA 0.68 7.26 0.37 2.62e-12 Mean platelet volume; LIHC cis rs4660306 1.000 rs2356559 chr1:45981512 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.56 -6.66 -0.34 1.11e-10 Homocysteine levels; LIHC cis rs561341 1.000 rs501312 chr17:30329066 A/G cg00745463 chr17:30367425 LRRC37B -0.79 -5.92 -0.3 7.98e-9 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs11779988 0.545 rs422746 chr8:17784486 C/A cg01800426 chr8:17659068 MTUS1 -0.42 -5.9 -0.3 8.53e-9 Breast cancer; LIHC cis rs7192750 0.586 rs8054175 chr16:71990424 G/A cg06353428 chr16:71660113 MARVELD3 0.8 9.06 0.44 1.02e-17 LDL cholesterol levels;Total cholesterol levels; LIHC trans rs1814175 0.645 rs847630 chr11:49926360 C/T cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg10802521 chr3:52805072 NEK4 0.4 6.76 0.34 5.84e-11 Electroencephalogram traits; LIHC cis rs9549367 0.789 rs57747440 chr13:113894750 C/A cg18105134 chr13:113819100 PROZ -0.66 -11.52 -0.53 3.63e-26 Platelet distribution width; LIHC cis rs11122272 0.735 rs2491407 chr1:231518928 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs10276381 0.685 rs56398224 chr7:28205748 A/AT cg23620719 chr7:28220237 JAZF1 0.63 6.96 0.35 1.72e-11 Crohn's disease; LIHC cis rs17384381 0.859 rs28529751 chr1:85910951 G/A cg16011679 chr1:85725395 C1orf52 0.81 8.46 0.42 7.83e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg16405210 chr4:1374714 KIAA1530 -0.9 -14.49 -0.62 1.9e-37 Longevity; LIHC cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.790 rs2256998 chr6:146207657 A/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.8 -0.3 1.51e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg15691649 chr6:25882328 NA -0.54 -7.81 -0.39 7.24e-14 Blood metabolite levels; LIHC cis rs7116495 1.000 rs10128658 chr11:71733519 C/T cg10381502 chr11:71823885 C11orf51 -0.54 -5.78 -0.3 1.73e-8 Severe influenza A (H1N1) infection; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg21747090 chr2:27597821 SNX17 -0.44 -6.55 -0.33 2.17e-10 Total body bone mineral density; LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg14159672 chr1:205819179 PM20D1 -0.71 -9.95 -0.47 1.18e-20 Menarche (age at onset); LIHC cis rs11098499 0.754 rs11724409 chr4:120252361 A/G cg09307838 chr4:120376055 NA 0.71 11.02 0.51 2.19e-24 Corneal astigmatism; LIHC cis rs3823572 0.564 rs2953619 chr7:133669649 C/G cg03336402 chr7:133662267 EXOC4 -0.49 -5.87 -0.3 1e-8 Intelligence (multi-trait analysis); LIHC cis rs4808199 0.649 rs17216693 chr19:19666574 T/C cg03709012 chr19:19516395 GATAD2A 1.0 13.94 0.6 2.67e-35 Nonalcoholic fatty liver disease; LIHC cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg18357526 chr6:26021779 HIST1H4A 0.54 7.49 0.38 6.1e-13 Blood metabolite levels; LIHC cis rs4332037 0.624 rs11766944 chr7:1888051 G/A cg23422044 chr7:1970798 MAD1L1 -0.54 -6.48 -0.33 3.14e-10 Bipolar disorder; LIHC cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg20607798 chr8:58055168 NA 0.59 6.93 0.35 2.13e-11 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.673 rs73265633 chr17:29236306 G/T cg13385521 chr17:29058706 SUZ12P 0.85 8.27 0.41 3.03e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G ch.8.2353618R chr8:119282796 SAMD12 -0.46 -6.14 -0.32 2.35e-9 Thyroid stimulating hormone; LIHC cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg21724239 chr8:58056113 NA 0.55 6.84 0.35 3.77e-11 Developmental language disorder (linguistic errors); LIHC cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.76 0.47 5.24e-20 Intelligence (multi-trait analysis); LIHC cis rs9733 0.650 rs2048558 chr1:150571730 A/G cg13175981 chr1:150552382 MCL1 0.63 9.87 0.47 2.14e-20 Tonsillectomy; LIHC cis rs8067545 0.611 rs2526477 chr17:20131193 A/G cg13482628 chr17:19912719 NA -0.46 -7.65 -0.38 2.1e-13 Schizophrenia; LIHC cis rs7481584 0.624 rs436580 chr11:3063961 T/G cg25174290 chr11:3078921 CARS -0.41 -6.0 -0.31 4.9e-9 Calcium levels; LIHC cis rs17106184 1.000 rs2095865 chr1:51299687 C/T cg07174182 chr1:51127561 FAF1 -0.63 -6.74 -0.34 6.65e-11 Type 2 diabetes; LIHC cis rs17125944 0.542 rs75723366 chr14:53256882 T/C cg13660082 chr14:53194042 PSMC6 -0.45 -7.4 -0.37 1.07e-12 Alzheimer's disease (late onset); LIHC trans rs7246657 0.943 rs10414904 chr19:37830088 G/A cg24637308 chr11:6592297 DNHD1 0.43 6.09 0.31 2.99e-9 Coronary artery calcification; LIHC cis rs7677751 0.708 rs2052699 chr4:55063994 C/T cg17187183 chr4:55093834 PDGFRA 0.59 7.49 0.38 6.04e-13 Corneal astigmatism; LIHC cis rs11955398 0.647 rs6449483 chr5:59995393 C/T cg02684056 chr5:59996105 DEPDC1B 0.43 6.14 0.32 2.24e-9 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.557 rs1250098 chr4:1238256 A/T cg20887711 chr4:1340912 KIAA1530 -0.71 -10.72 -0.5 2.64e-23 Obesity-related traits; LIHC cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.15e-51 Menopause (age at onset); LIHC cis rs17401966 0.838 rs12120191 chr1:10345772 A/G cg19773385 chr1:10388646 KIF1B -0.39 -7.07 -0.36 8.56e-12 Hepatocellular carcinoma; LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg07677032 chr17:61819896 STRADA 0.44 6.33 0.32 7.68e-10 Prudent dietary pattern; LIHC cis rs7107174 1.000 rs10899477 chr11:78052104 A/T cg02023728 chr11:77925099 USP35 0.47 8.93 0.43 2.6e-17 Testicular germ cell tumor; LIHC cis rs644799 0.544 rs499637 chr11:95569183 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.66 10.87 0.51 7.98e-24 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs1347297 0.526 rs6757186 chr2:179259719 G/C cg14011486 chr1:26737247 LIN28 0.51 7.84 0.39 5.61e-14 Alzheimer disease and age of onset; LIHC cis rs9467773 0.596 rs62396201 chr6:26668216 G/A cg11502198 chr6:26597334 ABT1 0.66 10.59 0.5 7.44e-23 Intelligence (multi-trait analysis); LIHC cis rs919433 0.679 rs1902249 chr2:198521356 T/C cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6831352 0.879 rs7672728 chr4:100055173 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs722599 0.748 rs2537824 chr14:75367349 T/C cg08847533 chr14:75593920 NEK9 -0.54 -8.77 -0.43 8.3e-17 IgG glycosylation; LIHC trans rs61931739 0.517 rs11052977 chr12:34035030 A/C cg26384229 chr12:38710491 ALG10B 0.51 7.02 0.35 1.18e-11 Morning vs. evening chronotype; LIHC cis rs9354308 1.000 rs9360161 chr6:66565457 C/T cg07460842 chr6:66804631 NA 0.49 5.8 0.3 1.47e-8 Metabolite levels; LIHC cis rs2050392 1.000 rs2489864 chr10:30693744 C/G cg25182066 chr10:30743637 MAP3K8 -0.45 -7.29 -0.37 2.17e-12 Inflammatory bowel disease; LIHC cis rs644799 0.562 rs1254989 chr11:95508121 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.66 9.74 0.47 5.88e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6963495 0.818 rs6977748 chr7:105167462 T/G cg19920283 chr7:105172520 RINT1 0.71 6.63 0.34 1.34e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg18252515 chr7:66147081 NA -1.24 -15.85 -0.65 7.92e-43 Diabetic kidney disease; LIHC cis rs6952808 0.531 rs3778998 chr7:2180753 C/A cg20295408 chr7:1910781 MAD1L1 -0.4 -5.77 -0.3 1.76e-8 Bipolar disorder and schizophrenia; LIHC cis rs7772486 0.875 rs9399572 chr6:146362945 T/G cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.21e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs3960554 0.709 rs73138006 chr7:75769990 T/C cg19862616 chr7:65841803 NCRNA00174 0.6 8.17 0.4 6.14e-15 Eotaxin levels; LIHC cis rs644799 0.672 rs61902245 chr11:95517737 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.78 13.42 0.59 2.81e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9399137 0.507 rs11753673 chr6:135316476 T/C cg24558204 chr6:135376177 HBS1L 0.61 10.4 0.49 3.53e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs10751667 0.621 rs10794353 chr11:948740 A/G cg06064525 chr11:970664 AP2A2 -0.56 -14.94 -0.63 3.24e-39 Alzheimer's disease (late onset); LIHC cis rs1144333 1.000 rs5745392 chr1:76306809 C/T cg03433033 chr1:76189801 ACADM 0.58 8.77 0.43 8.65e-17 Attention function in attention deficit hyperactive disorder; LIHC cis rs1707322 1.000 rs10890377 chr1:46406594 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.85e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9790314 1.000 rs1382426 chr3:161045933 G/A cg04691961 chr3:161091175 C3orf57 -0.42 -6.64 -0.34 1.25e-10 Morning vs. evening chronotype; LIHC cis rs7089973 0.604 rs11196924 chr10:116571796 A/C cg03647239 chr10:116582469 FAM160B1 -0.42 -5.75 -0.3 2.03e-8 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg06873352 chr17:61820015 STRADA 0.72 12.21 0.55 1.04e-28 Prudent dietary pattern; LIHC cis rs2073499 1.000 rs79499880 chr3:50259551 A/G cg03645007 chr3:50255295 SLC38A3 0.49 5.91 0.3 8.29e-9 Schizophrenia; LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg11062466 chr8:58055876 NA 0.51 7.5 0.38 5.48e-13 Developmental language disorder (linguistic errors); LIHC cis rs17826219 0.568 rs9903854 chr17:29153998 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.01 0.4 1.79e-14 Body mass index; LIHC cis rs7238033 0.560 rs2170974 chr18:43308810 A/T cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs929354 0.772 rs3802125 chr7:156970563 A/C cg05182265 chr7:156933206 UBE3C -0.33 -6.14 -0.31 2.35e-9 Body mass index; LIHC cis rs9814567 0.752 rs13084192 chr3:134336095 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 9.1 0.44 7.53e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7945718 0.875 rs6486057 chr11:12810338 T/A cg25843174 chr11:12811716 TEAD1 0.37 8.52 0.42 5.28e-16 Educational attainment (years of education); LIHC cis rs748404 0.578 rs552701 chr15:43613810 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.59 10.53 0.49 1.2e-22 Lung cancer; LIHC cis rs2153535 0.580 rs1928184 chr6:8532108 T/A cg23788917 chr6:8435910 SLC35B3 0.63 8.97 0.44 1.97e-17 Motion sickness; LIHC cis rs3008870 1.000 rs2985797 chr1:67431499 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.93 -15.44 -0.64 3.63e-41 Lymphocyte percentage of white cells; LIHC cis rs2153535 0.580 rs6597322 chr6:8449952 T/G cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC trans rs208520 0.690 rs12192710 chr6:66718137 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.91 0.43 3.16e-17 Exhaled nitric oxide output; LIHC cis rs7953249 0.807 rs2393775 chr12:121424574 G/A cg02403541 chr12:121454288 C12orf43 -0.37 -6.3 -0.32 9.4e-10 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs2276314 1.000 rs58054756 chr18:33554053 G/C cg05985134 chr18:33552581 C18orf21 0.49 5.86 0.3 1.11e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs3736594 0.513 rs62141278 chr2:27768381 C/T cg27432699 chr2:27873401 GPN1 0.46 6.85 0.35 3.39e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs7927592 0.731 rs2840367 chr11:68302101 G/A cg16797656 chr11:68205561 LRP5 -0.51 -9.02 -0.44 1.34e-17 Total body bone mineral density; LIHC cis rs13256369 1.000 rs10110591 chr8:8576608 G/T cg18904891 chr8:8559673 CLDN23 -0.77 -14.4 -0.61 4.35e-37 Obesity-related traits; LIHC cis rs12497850 0.931 rs7627404 chr3:48819668 A/C cg07636037 chr3:49044803 WDR6 0.93 16.69 0.67 3.72e-46 Parkinson's disease; LIHC cis rs12922317 0.964 rs16958789 chr16:12075648 G/A cg09319797 chr16:12061715 TNFRSF17 0.42 7.28 0.37 2.33e-12 Schizophrenia; LIHC cis rs7208859 0.673 rs9894876 chr17:29182020 G/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1814175 0.817 rs12295885 chr11:50036762 T/G cg15704280 chr7:45808275 SEPT13 -1.0 -23.71 -0.79 3.38e-74 Height; LIHC cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.89 0.51 6.65e-24 Colorectal cancer; LIHC cis rs6430585 0.528 rs78274583 chr2:136734569 C/T cg07305463 chr2:136567211 LCT -0.38 -5.81 -0.3 1.42e-8 Corneal structure; LIHC cis rs8062405 1.000 rs56358680 chr16:28843118 A/G cg00204512 chr16:28754710 NA 0.34 6.37 0.33 6.01e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg11890956 chr21:40555474 PSMG1 -1.07 -15.09 -0.63 8.6e-40 Cognitive function; LIHC cis rs9309473 0.898 rs11126404 chr2:73796924 T/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.77 -0.34 5.56e-11 Metabolite levels; LIHC cis rs8062405 0.698 rs8046545 chr16:28915217 G/A cg07451762 chr16:28383216 NA -0.36 -6.38 -0.33 5.76e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg11707391 chr8:10001627 MSRA -0.47 -6.12 -0.31 2.63e-9 Monocyte count; LIHC cis rs138880 0.542 rs9616210 chr22:50317346 C/T cg09182678 chr22:50328711 NA -0.7 -8.06 -0.4 1.28e-14 Schizophrenia; LIHC cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.33 0.45 1.36e-18 Platelet count; LIHC cis rs7100689 0.646 rs10736348 chr10:82139244 C/A cg00277334 chr10:82204260 NA -0.57 -7.44 -0.37 8.36e-13 Post bronchodilator FEV1; LIHC cis rs1005277 0.579 rs932538 chr10:38381314 T/C cg00409905 chr10:38381863 ZNF37A -0.59 -10.31 -0.49 6.75e-22 Extrinsic epigenetic age acceleration; LIHC cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 8.95 0.44 2.31e-17 Bipolar disorder; LIHC cis rs7107174 0.901 rs2450136 chr11:77925273 T/G cg02023728 chr11:77925099 USP35 0.54 10.53 0.49 1.24e-22 Testicular germ cell tumor; LIHC cis rs7208859 0.673 rs12949860 chr17:29223032 A/G cg13385521 chr17:29058706 SUZ12P 0.79 7.88 0.39 4.55e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6788895 1.000 rs41372346 chr3:150489116 C/G cg09723797 chr3:150481914 SIAH2 0.81 10.89 0.51 6.69e-24 Breast cancer; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25195416 chr21:46696626 POFUT2 0.4 6.11 0.31 2.78e-9 Bilirubin levels; LIHC cis rs3780378 0.682 rs7861763 chr9:5273194 C/T cg02405213 chr9:5042618 JAK2 -0.48 -8.22 -0.41 4.21e-15 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs3812831 0.543 rs389108 chr13:114925389 A/G cg06611532 chr13:114900021 NA 0.42 7.7 0.38 1.51e-13 Schizophrenia; LIHC cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg10360323 chr17:41437877 NA 0.39 5.71 0.3 2.44e-8 Menopause (age at onset); LIHC cis rs10744422 0.800 rs2343110 chr12:123343571 T/G cg22842854 chr12:123319900 HIP1R -0.74 -9.76 -0.47 5.12e-20 Schizophrenia; LIHC cis rs12477438 0.520 rs13031919 chr2:99848932 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.57 9.96 0.47 1.08e-20 Chronic sinus infection; LIHC cis rs11758351 0.925 rs10452600 chr6:26192502 C/A cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC cis rs4722404 0.502 rs7804033 chr7:3110005 G/A cg19214707 chr7:3157722 NA -0.33 -5.78 -0.3 1.72e-8 Atopic dermatitis; LIHC cis rs12586317 0.690 rs56797330 chr14:35833078 G/A cg03549618 chr14:35838977 NA -0.38 -6.06 -0.31 3.65e-9 Psoriasis; LIHC cis rs9503598 0.502 rs6923831 chr6:3430889 T/A cg00476032 chr6:3446245 SLC22A23 -0.32 -5.85 -0.3 1.18e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03004097 chr2:239197782 PER2 0.49 6.17 0.32 1.9e-9 Lung function (FEV1/FVC); LIHC cis rs3106136 0.546 rs7685121 chr4:95175682 G/A cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.27 -0.45 2.08e-18 Capecitabine sensitivity; LIHC cis rs9640161 0.789 rs28432021 chr7:150046235 G/C cg17279839 chr7:150038598 RARRES2 0.58 12.11 0.55 2.54e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs5769765 0.526 rs5770722 chr22:50253220 G/C cg22709217 chr22:50311962 ALG12;CRELD2 0.58 5.81 0.3 1.44e-8 Schizophrenia; LIHC cis rs7246657 0.943 rs10405325 chr19:37883477 G/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs11690935 0.921 rs4668414 chr2:172704291 A/C cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.35 -0.68 7.89e-49 Schizophrenia; LIHC cis rs7312933 0.558 rs1669886 chr12:42838240 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.12 -0.4 8.3e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7927771 0.864 rs755554 chr11:47432034 G/C cg20307385 chr11:47447363 PSMC3 0.51 6.69 0.34 9.2e-11 Subjective well-being; LIHC cis rs5769765 1.000 rs5770755 chr22:50280136 T/C cg02269571 chr22:50332266 NA 0.6 8.42 0.41 1.06e-15 Schizophrenia; LIHC cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg10295955 chr4:187884368 NA -0.97 -23.17 -0.78 4.65e-72 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.830 rs12673450 chr7:66009220 G/A cg18252515 chr7:66147081 NA -0.48 -7.01 -0.35 1.27e-11 Aortic root size; LIHC cis rs7959452 0.868 rs12812860 chr12:69746671 T/C cg20891283 chr12:69753455 YEATS4 0.7 11.99 0.54 6.64e-28 Blood protein levels; LIHC cis rs644799 0.544 rs56298021 chr11:95545113 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.69 11.46 0.53 6.13e-26 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24520871 chr10:73074265 NA 0.46 6.63 0.34 1.33e-10 Pancreatic cancer; LIHC cis rs4332037 0.510 rs11762803 chr7:1886805 A/G cg23422044 chr7:1970798 MAD1L1 -0.54 -8.8 -0.43 6.91e-17 Bipolar disorder; LIHC cis rs875971 0.862 rs11763189 chr7:65983529 G/A cg11764359 chr7:65958608 NA 0.85 15.43 0.64 3.77e-41 Aortic root size; LIHC cis rs7617773 0.815 rs9825637 chr3:48372282 T/C cg11946769 chr3:48343235 NME6 0.91 11.87 0.54 1.84e-27 Coronary artery disease; LIHC cis rs10751667 1.000 rs6597972 chr11:928402 C/T cg06064525 chr11:970664 AP2A2 -0.49 -12.06 -0.55 3.65e-28 Alzheimer's disease (late onset); LIHC cis rs2016586 0.929 rs5999961 chr22:36105275 A/C cg26342177 chr22:36113512 APOL5 -0.38 -6.22 -0.32 1.41e-9 Body mass index; LIHC cis rs9303401 0.614 rs3803753 chr17:56540110 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.92 12.58 0.56 4.44e-30 Cognitive test performance; LIHC cis rs8067545 0.750 rs7208365 chr17:19998017 T/G cg13482628 chr17:19912719 NA 0.49 8.2 0.41 4.99e-15 Schizophrenia; LIHC cis rs2607426 0.681 rs2303723 chr19:41230995 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.52 -6.2 -0.32 1.67e-9 Blood protein levels; LIHC cis rs7959452 0.868 rs10784774 chr12:69737879 C/T cg20891283 chr12:69753455 YEATS4 -0.69 -11.88 -0.54 1.69e-27 Blood protein levels; LIHC trans rs3960554 0.599 rs56090527 chr7:75762125 A/C cg19862616 chr7:65841803 NCRNA00174 0.59 8.15 0.4 6.91e-15 Eotaxin levels; LIHC cis rs6840360 0.598 rs11944921 chr4:152731109 A/G cg22705602 chr4:152727874 NA 0.29 6.09 0.31 3.05e-9 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs4974484 chr3:134219019 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.06 -0.31 3.65e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1878931 0.513 rs35160989 chr16:3405506 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.83 14.32 0.61 9.09e-37 Body mass index (adult); LIHC cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg02503808 chr4:7069936 GRPEL1 0.8 12.01 0.54 5.61e-28 Monocyte percentage of white cells; LIHC cis rs3768617 0.565 rs3768626 chr1:183078462 A/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.67 0.5 3.84e-23 Fuchs's corneal dystrophy; LIHC cis rs7100689 0.784 rs10749578 chr10:82139115 A/G cg01528321 chr10:82214614 TSPAN14 -0.89 -13.02 -0.58 9.67e-32 Post bronchodilator FEV1; LIHC cis rs2404602 0.716 rs1125932 chr15:76820540 C/T cg03037974 chr15:76606532 NA 0.74 14.45 0.62 2.85e-37 Blood metabolite levels; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg26354017 chr1:205819088 PM20D1 0.77 11.29 0.52 2.47e-25 Menarche (age at onset); LIHC trans rs4596713 0.508 rs7862404 chr9:71779903 G/A cg16512924 chr15:28394682 HERC2 0.39 6.25 0.32 1.21e-9 Headache; LIHC cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.68 0.34 9.43e-11 Bipolar disorder; LIHC cis rs7917772 0.582 rs7087984 chr10:104380686 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.59 0.38 3e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6546550 0.935 rs2305523 chr2:70039677 G/T cg02498382 chr2:70120550 SNRNP27 0.39 6.42 0.33 4.68e-10 Prevalent atrial fibrillation; LIHC trans rs11098499 0.657 rs71614442 chr4:120379346 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs7772486 0.692 rs1577916 chr6:146069789 G/A cg13319975 chr6:146136371 FBXO30 0.4 6.61 0.34 1.46e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs73001065 0.901 rs73004951 chr19:19695228 C/T cg03709012 chr19:19516395 GATAD2A 0.91 8.08 0.4 1.13e-14 LDL cholesterol; LIHC cis rs2797685 0.853 rs707462 chr1:7849880 A/G cg04725166 chr1:7887271 PER3 -0.41 -7.51 -0.38 5.08e-13 Crohn's disease; LIHC cis rs1878931 0.507 rs8054222 chr16:3413477 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.64 -7.67 -0.38 1.85e-13 Body mass index (adult); LIHC cis rs4819052 0.851 rs2838857 chr21:46681000 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.82 0.39 6.69e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11711311 1.000 rs3806641 chr3:113465761 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.89 -0.35 2.62e-11 IgG glycosylation; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17461271 chr1:172717683 NA 0.34 6.29 0.32 9.84e-10 Immature fraction of reticulocytes; LIHC trans rs1434538 0.837 rs7694131 chr4:96064089 A/G cg16708938 chr21:44832350 NA -0.32 -6.07 -0.31 3.47e-9 Coronary artery disease; LIHC cis rs853679 0.824 rs1321505 chr6:28052823 A/C cg16479474 chr6:28041457 NA 0.5 5.88 0.3 9.81e-9 Depression; LIHC cis rs875971 0.798 rs57739047 chr7:65972566 A/T cg11764359 chr7:65958608 NA 0.85 15.3 0.64 1.23e-40 Aortic root size; LIHC cis rs2012796 0.956 rs7146802 chr14:81820515 A/G cg02996355 chr14:81879375 NA 0.45 6.72 0.34 7.71e-11 Night sleep phenotypes; LIHC cis rs1008375 1.000 rs7671752 chr4:17661398 C/T cg16339924 chr4:17578868 LAP3 0.43 6.15 0.32 2.22e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg11890956 chr21:40555474 PSMG1 -0.47 -7.67 -0.38 1.83e-13 Cognitive function; LIHC cis rs2073499 1.000 rs2073498 chr3:50369546 C/A cg03645007 chr3:50255295 SLC38A3 0.51 6.05 0.31 3.89e-9 Schizophrenia; LIHC cis rs5769765 1.000 rs5770728 chr22:50259984 G/A cg26441486 chr22:50317300 CRELD2 -0.33 -5.91 -0.3 8.35e-9 Schizophrenia; LIHC cis rs1865721 0.761 rs11660256 chr18:73219532 C/T cg26385618 chr18:73139727 C18orf62 -0.27 -6.83 -0.35 3.94e-11 Intelligence; LIHC cis rs2073300 0.609 rs3827085 chr20:23356985 A/T cg12062639 chr20:23401060 NAPB 1.08 14.3 0.61 1.05e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4243830 0.850 rs908273 chr1:6588604 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.78 -9.66 -0.46 1.1e-19 Body mass index; LIHC trans rs2262909 0.925 rs73019900 chr19:22286680 G/A cg05197062 chr11:11642011 GALNTL4 0.43 6.34 0.32 7.14e-10 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs360798 0.532 rs2136737 chr2:62969310 G/C cg17519650 chr2:63277830 OTX1 -0.53 -8.14 -0.4 7.53e-15 Coronary artery disease; LIHC cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.72 0.3 2.33e-8 Electroencephalogram traits; LIHC cis rs7103411 0.637 rs7116850 chr11:27645530 C/T cg18117895 chr11:27722066 BDNF -0.46 -6.51 -0.33 2.61e-10 Menarche (age at onset);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs77633900 0.614 rs280008 chr15:77011815 T/C cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs7772486 0.790 rs6917135 chr6:146152426 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.83 0.3 1.3e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs875971 1.000 rs6961990 chr7:65888570 C/A cg10756647 chr7:56101905 PSPH 0.45 6.64 0.34 1.2e-10 Aortic root size; LIHC cis rs2274273 0.870 rs17741831 chr14:55816715 T/A cg01864836 chr14:55583639 NA -0.37 -6.59 -0.34 1.66e-10 Protein biomarker; LIHC cis rs80282103 0.571 rs10047269 chr10:1103058 G/A cg18964960 chr10:1102726 WDR37 0.67 6.24 0.32 1.29e-9 Glomerular filtration rate (creatinine); LIHC cis rs12142240 0.698 rs4372193 chr1:46853233 G/T cg00530320 chr1:46809349 NSUN4 0.53 5.77 0.3 1.82e-8 Menopause (age at onset); LIHC cis rs10751667 0.666 rs7396509 chr11:956761 G/A cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.09e-12 Alzheimer's disease (late onset); LIHC cis rs4423214 0.879 rs12803256 chr11:71132868 A/G cg24826892 chr11:71159390 DHCR7 0.54 7.09 0.36 7.79e-12 Vitamin D levels; LIHC cis rs74233809 1.000 rs12219304 chr10:104931584 G/C cg03493300 chr10:104813866 CNNM2 0.47 6.02 0.31 4.57e-9 Birth weight; LIHC trans rs2243480 1.000 rs2533288 chr7:66056711 C/G cg07424592 chr7:64974309 NA 0.77 8.87 0.43 4.13e-17 Diabetic kidney disease; LIHC cis rs6951245 1.000 rs2363286 chr7:1091625 A/G cg08132940 chr7:1081526 C7orf50 -0.81 -7.01 -0.35 1.26e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11098499 0.863 rs7699064 chr4:120428309 A/G cg09307838 chr4:120376055 NA -0.75 -11.12 -0.52 1.03e-24 Corneal astigmatism; LIHC cis rs10751667 0.961 rs7395303 chr11:986221 T/A cg06064525 chr11:970664 AP2A2 -0.5 -12.26 -0.55 7.1e-29 Alzheimer's disease (late onset); LIHC cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.88 0.3 9.86e-9 Menopause (age at onset); LIHC cis rs9308433 0.529 rs1391553 chr1:214474119 T/C cg06198575 chr1:214491504 SMYD2 0.55 5.78 0.3 1.71e-8 IgG glycosylation; LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg07167872 chr1:205819463 PM20D1 0.63 9.26 0.45 2.34e-18 Menarche (age at onset); LIHC cis rs7927592 0.913 rs10047412 chr11:68232912 T/C cg01657329 chr11:68192670 LRP5 -0.46 -6.0 -0.31 4.92e-9 Total body bone mineral density; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00437311 chr19:37178174 NA 0.51 8.3 0.41 2.52e-15 Calcium levels; LIHC cis rs7944735 0.508 rs7115371 chr11:47564587 G/A cg20307385 chr11:47447363 PSMC3 -0.52 -5.86 -0.3 1.07e-8 Intraocular pressure; LIHC cis rs7208859 0.623 rs78071511 chr17:29128154 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3806843 1.000 rs3806845 chr5:140180737 C/T cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.61e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs577948 0.770 rs488062 chr11:122050913 A/G cg10262710 chr11:122074011 LOC399959 0.36 6.2 0.32 1.62e-9 Myopia (pathological); LIHC cis rs4555082 0.874 rs2816620 chr14:105732704 G/T cg06808227 chr14:105710500 BRF1 -0.49 -6.05 -0.31 3.79e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg24531977 chr5:56204891 C5orf35 -0.7 -9.81 -0.47 3.51e-20 Initial pursuit acceleration; LIHC cis rs35110281 0.713 rs6518310 chr21:45098670 T/A cg04455712 chr21:45112962 RRP1B 0.53 9.21 0.45 3.26e-18 Mean corpuscular volume; LIHC cis rs72781680 0.611 rs78861366 chr2:24354428 A/G cg06627628 chr2:24431161 ITSN2 -0.62 -7.31 -0.37 1.88e-12 Lymphocyte counts; LIHC cis rs12477438 0.520 rs11883676 chr2:99800814 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.16 0.77 4.33e-68 Chronic sinus infection; LIHC cis rs208520 0.690 rs12198297 chr6:66714665 G/A cg07460842 chr6:66804631 NA 0.78 9.03 0.44 1.31e-17 Exhaled nitric oxide output; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00367488 chr2:120020686 STEAP3 0.38 6.06 0.31 3.6e-9 Bilirubin levels; LIHC cis rs6665290 0.935 rs11588904 chr1:227196211 T/C cg10327440 chr1:227177885 CDC42BPA -1.18 -25.93 -0.81 1e-82 Myeloid white cell count; LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg00091569 chr3:40428383 ENTPD3 0.39 6.74 0.34 6.75e-11 Renal cell carcinoma; LIHC cis rs35110281 0.693 rs11089093 chr21:45121161 C/T cg21573476 chr21:45109991 RRP1B -0.52 -10.11 -0.48 3.52e-21 Mean corpuscular volume; LIHC cis rs12188164 0.543 rs2672722 chr5:453567 G/A cg24955955 chr5:415729 AHRR 0.32 6.64 0.34 1.26e-10 Cystic fibrosis severity; LIHC trans rs8073060 0.827 rs66878360 chr17:33866337 C/A cg19694781 chr19:47549865 TMEM160 0.63 6.7 0.34 8.77e-11 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs3892630 0.612 rs10413282 chr19:33182751 A/G cg22980127 chr19:33182716 NUDT19 1.15 19.06 0.72 1.07e-55 Red blood cell traits; LIHC cis rs77633900 0.614 rs2468113 chr15:76851421 G/C cg21673338 chr15:77095150 SCAPER -0.5 -6.84 -0.35 3.62e-11 Non-glioblastoma glioma;Glioma; LIHC cis rs4820294 0.770 rs7285699 chr22:38066556 A/C cg10587741 chr22:38071170 LGALS1 0.44 7.76 0.39 9.85e-14 Fat distribution (HIV); LIHC cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg21724239 chr8:58056113 NA 0.61 7.53 0.38 4.65e-13 Developmental language disorder (linguistic errors); LIHC cis rs7789940 1.000 rs11765693 chr7:75985373 A/G cg10167463 chr7:75959203 YWHAG -0.43 -6.84 -0.35 3.56e-11 Multiple sclerosis; LIHC cis rs7818688 0.653 rs11783522 chr8:95886624 G/A cg16049864 chr8:95962084 TP53INP1 0.58 6.37 0.33 6.09e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs9318086 0.648 rs7331047 chr13:24467342 T/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.56 10.88 0.51 7.15e-24 Myopia (pathological); LIHC cis rs2749592 0.611 rs176888 chr10:38406161 C/A cg25427524 chr10:38739819 LOC399744 -0.64 -11.44 -0.53 7.15e-26 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg18357526 chr6:26021779 HIST1H4A -0.52 -6.97 -0.35 1.62e-11 Blood metabolite levels; LIHC cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg04944784 chr2:26401820 FAM59B 0.72 9.33 0.45 1.36e-18 Gut microbiome composition (summer); LIHC trans rs8073060 0.614 rs225275 chr17:33972567 G/C cg19694781 chr19:47549865 TMEM160 -1.27 -14.15 -0.61 4.12e-36 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg14393609 chr7:65229607 NA -0.39 -6.59 -0.34 1.7e-10 Calcium levels; LIHC cis rs6942756 0.774 rs2402944 chr7:128951402 G/T cg02491457 chr7:128862824 NA -0.56 -8.56 -0.42 3.84e-16 White matter hyperintensity burden; LIHC cis rs9816226 0.938 rs55742087 chr3:185830488 C/T cg00760338 chr3:185826511 ETV5 -0.7 -6.37 -0.33 6.05e-10 Obesity;Body mass index; LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.96e-16 Prudent dietary pattern; LIHC cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.68 11.01 0.51 2.38e-24 Height; LIHC cis rs986417 0.579 rs1254281 chr14:60854300 T/C cg27398547 chr14:60952738 C14orf39 -0.76 -8.81 -0.43 6.55e-17 Gut microbiota (bacterial taxa); LIHC cis rs765787 0.530 rs2554456 chr15:45521138 A/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.73 -0.3 2.15e-8 Uric acid levels; LIHC cis rs11792861 0.926 rs75472294 chr9:111804239 G/A cg05043794 chr9:111880884 C9orf5 -0.3 -6.88 -0.35 2.87e-11 Menarche (age at onset); LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg13409248 chr3:40428643 ENTPD3 0.47 7.79 0.39 8.02e-14 Renal cell carcinoma; LIHC cis rs910316 0.934 rs8016330 chr14:75657507 G/T cg11812906 chr14:75593930 NEK9 -0.69 -13.22 -0.58 1.61e-32 Height; LIHC cis rs45535039 0.506 rs4936467 chr11:119086629 A/T cg16724696 chr11:118992527 HINFP -0.51 -6.99 -0.35 1.48e-11 Plateletcrit; LIHC cis rs17401966 0.522 rs946504 chr1:10308597 T/C cg19773385 chr1:10388646 KIF1B -0.33 -6.09 -0.31 3.03e-9 Hepatocellular carcinoma; LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg24846343 chr22:24311635 DDTL 0.74 15.15 0.63 4.77e-40 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg05025164 chr4:1340916 KIAA1530 -0.4 -6.02 -0.31 4.56e-9 Obesity-related traits; LIHC cis rs11690935 0.959 rs76324055 chr2:172620150 T/A cg13550731 chr2:172543902 DYNC1I2 -0.94 -17.68 -0.69 3.78e-50 Schizophrenia; LIHC cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg11301795 chr4:187892539 NA -0.27 -7.17 -0.36 4.67e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769765 0.658 rs2157536 chr22:50190180 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.54 -6.53 -0.33 2.35e-10 Schizophrenia; LIHC cis rs6088580 0.634 rs6120650 chr20:33039973 G/A cg08999081 chr20:33150536 PIGU 0.67 13.3 0.58 7.93e-33 Glomerular filtration rate (creatinine); LIHC cis rs9291683 0.595 rs10939665 chr4:10037628 T/C cg11266682 chr4:10021025 SLC2A9 0.35 7.44 0.37 8.24e-13 Bone mineral density; LIHC cis rs1707322 0.721 rs12091503 chr1:46107868 T/C cg06784218 chr1:46089804 CCDC17 0.42 7.87 0.39 4.71e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs644148 0.770 rs2571113 chr19:44999814 A/G cg15540054 chr19:45004280 ZNF180 -0.77 -11.49 -0.53 4.46e-26 Personality dimensions; LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs2236918 0.710 rs1776174 chr1:242031839 G/T cg17736920 chr1:242011382 EXO1 0.41 5.97 0.31 5.86e-9 Menopause (age at onset); LIHC cis rs826838 0.935 rs1843639 chr12:39178919 C/A cg26384229 chr12:38710491 ALG10B 0.85 10.99 0.51 2.87e-24 Heart rate; LIHC cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg26818010 chr10:134567672 INPP5A -0.73 -9.43 -0.45 6.56e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6598955 0.724 rs884533 chr1:26585657 G/T cg00852783 chr1:26633632 UBXN11 0.5 8.39 0.41 1.27e-15 Obesity-related traits; LIHC cis rs1552244 0.554 rs7638846 chr3:10048601 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.43 -6.37 -0.33 6.14e-10 Alzheimer's disease; LIHC cis rs2455826 0.500 rs2455852 chr3:15688688 C/T cg16303742 chr3:15540471 COLQ -0.36 -6.09 -0.31 3.01e-9 Inflammatory skin disease; LIHC cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg22105103 chr4:187893119 NA 0.35 8.81 0.43 6.52e-17 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11172286 chr11:47600544 KBTBD4;NDUFS3 0.45 6.17 0.32 1.98e-9 Lung function (FEV1/FVC); LIHC cis rs6963495 0.651 rs3892298 chr7:105152187 A/G cg19920283 chr7:105172520 RINT1 0.67 6.19 0.32 1.73e-9 Bipolar disorder (body mass index interaction); LIHC cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg02931644 chr1:25747376 RHCE 0.38 8.35 0.41 1.78e-15 Erythrocyte sedimentation rate; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03387256 chr10:90750898 FAS;ACTA2 0.4 6.24 0.32 1.31e-9 Cognitive function; LIHC cis rs9517320 0.534 rs9556962 chr13:99156648 C/T cg07423050 chr13:99094983 FARP1 -0.5 -8.94 -0.44 2.5e-17 Longevity; LIHC cis rs1707322 1.000 rs10890372 chr1:46391020 T/G cg03146154 chr1:46216737 IPP 0.47 7.62 0.38 2.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1784581 0.802 rs9458430 chr6:162426517 G/T cg17173639 chr6:162384350 PARK2 -0.61 -10.75 -0.5 2.11e-23 Itch intensity from mosquito bite; LIHC cis rs7116495 0.609 rs6592447 chr11:71641093 A/T cg26138937 chr11:71823887 C11orf51 -1.22 -9.87 -0.47 2.26e-20 Severe influenza A (H1N1) infection; LIHC trans rs7615952 0.688 rs12638224 chr3:125541320 C/T cg07211511 chr3:129823064 LOC729375 -0.49 -7.61 -0.38 2.74e-13 Blood pressure (smoking interaction); LIHC cis rs4319547 0.620 rs12372756 chr12:122815130 A/G cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.27 -0.37 2.46e-12 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13626624 chr20:656518 SCRT2 0.49 6.45 0.33 3.88e-10 Lung function (FEV1/FVC); LIHC trans rs1814175 0.607 rs11493324 chr11:50011304 T/C cg03929089 chr4:120376271 NA -0.62 -10.68 -0.5 3.6e-23 Height; LIHC cis rs61008539 0.815 rs6960062 chr7:884665 A/G cg15782153 chr7:917662 C7orf20 0.37 5.92 0.3 7.78e-9 Perceived unattractiveness to mosquitoes; LIHC trans rs2073499 0.935 rs3755832 chr3:50305234 G/A cg21659725 chr3:3221576 CRBN 0.6 6.07 0.31 3.36e-9 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg15330255 chr10:103454985 FBXW4 0.47 6.42 0.33 4.59e-10 Hepatitis; LIHC cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg24101359 chr6:42928495 GNMT 0.46 6.23 0.32 1.4e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6691722 0.503 rs2274168 chr1:24707211 G/T cg18323236 chr1:24743029 NIPAL3 0.41 7.44 0.37 8.21e-13 Response to interferon beta in multiple sclerosis; LIHC cis rs1005277 0.579 rs1780116 chr10:38526621 C/T cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.78 -0.3 1.67e-8 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.805 rs11522896 chr12:38234427 T/C cg13010199 chr12:38710504 ALG10B 0.5 5.85 0.3 1.14e-8 Bladder cancer; LIHC cis rs4790333 0.845 rs7210932 chr17:2272024 A/G cg02569219 chr17:2266849 SGSM2 -0.63 -10.14 -0.48 2.6e-21 Proinsulin levels; LIHC cis rs6540556 0.769 rs17389198 chr1:209922058 G/A cg05527609 chr1:210001259 C1orf107 -0.69 -9.82 -0.47 3.15e-20 Red blood cell count; LIHC cis rs875971 0.545 rs12673308 chr7:65631361 C/A cg11764359 chr7:65958608 NA 0.51 7.08 0.36 8.1e-12 Aortic root size; LIHC cis rs929354 0.739 rs1182439 chr7:157027367 G/A cg16102536 chr7:156981717 UBE3C -0.35 -5.81 -0.3 1.41e-8 Body mass index; LIHC cis rs1552244 0.572 rs41464050 chr3:10158393 A/G cg00149659 chr3:10157352 C3orf10 0.89 8.75 0.43 9.84e-17 Alzheimer's disease; LIHC cis rs11711311 1.000 rs16861312 chr3:113492402 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.37 -6.72 -0.34 7.69e-11 IgG glycosylation; LIHC cis rs1707322 1.000 rs4660889 chr1:46297331 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.35 0.32 6.71e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs782590 0.967 rs17798852 chr2:55805172 A/C cg03859395 chr2:55845619 SMEK2 0.86 15.51 0.64 1.78e-41 Metabolic syndrome; LIHC cis rs4788570 0.615 rs7195059 chr16:71718366 C/T cg06353428 chr16:71660113 MARVELD3 1.4 14.37 0.61 5.77e-37 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg06873352 chr17:61820015 STRADA 0.7 12.13 0.55 2.11e-28 Prudent dietary pattern; LIHC cis rs10779751 1.000 rs2016559 chr1:11269917 G/T cg08854313 chr1:11322531 MTOR 0.79 11.18 0.52 6.27e-25 Body mass index; LIHC cis rs344364 0.511 rs1742468 chr16:1950243 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.27 -0.37 2.54e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs2832191 1.000 rs8131214 chr21:30483386 T/G cg24692254 chr21:30365293 RNF160 -0.63 -11.24 -0.52 3.79e-25 Dental caries; LIHC cis rs4684776 0.935 rs6781986 chr3:11374899 T/A cg00170343 chr3:11313890 ATG7 -0.51 -6.84 -0.35 3.66e-11 Small vessel stroke; LIHC cis rs9902453 0.808 rs78154346 chr17:28169493 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.98 0.54 7.79e-28 Coffee consumption (cups per day); LIHC cis rs2635047 0.934 rs11663321 chr18:44622704 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.48 6.43 0.33 4.32e-10 Educational attainment; LIHC cis rs7582720 0.945 rs116773016 chr2:203811902 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs17539620 0.624 rs62432738 chr6:154835674 T/C cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs12497850 0.864 rs12493001 chr3:49181885 A/G cg07636037 chr3:49044803 WDR6 0.88 15.14 0.63 5.21e-40 Parkinson's disease; LIHC cis rs12980942 1.000 rs2241719 chr19:41829581 T/A cg25627403 chr19:41769009 HNRNPUL1 0.56 6.81 0.35 4.29e-11 Coronary artery disease; LIHC cis rs2839186 0.587 rs35679325 chr21:47640980 A/G cg12016809 chr21:47604291 C21orf56 -0.4 -5.94 -0.31 6.91e-9 Testicular germ cell tumor; LIHC cis rs921968 0.565 rs7599365 chr2:219620566 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9828933 0.938 rs3816157 chr3:63999322 G/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.85 -10.43 -0.49 2.73e-22 Type 2 diabetes; LIHC cis rs1697139 0.604 rs874550 chr5:66530945 C/T cg16691251 chr5:66510806 NA -0.46 -6.2 -0.32 1.63e-9 Breast cancer; LIHC cis rs9790314 0.586 rs11710916 chr3:161130070 A/G cg17135325 chr3:160939158 NMD3 0.48 7.2 0.36 3.87e-12 Morning vs. evening chronotype; LIHC cis rs7246657 1.000 rs1823061 chr19:37800626 G/A cg23950597 chr19:37808831 NA -0.5 -6.36 -0.33 6.62e-10 Coronary artery calcification; LIHC cis rs7520050 0.966 rs1768816 chr1:46528599 T/C cg03146154 chr1:46216737 IPP -0.37 -6.02 -0.31 4.45e-9 Red blood cell count;Reticulocyte count; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg13639582 chr19:49402099 TULP2 0.42 6.1 0.31 2.81e-9 Immature fraction of reticulocytes; LIHC cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg06640241 chr16:89574553 SPG7 0.87 15.76 0.65 1.94e-42 Multiple myeloma (IgH translocation); LIHC cis rs7116495 0.529 rs575871 chr11:71778822 A/G cg10381502 chr11:71823885 C11orf51 -0.91 -8.83 -0.43 5.64e-17 Severe influenza A (H1N1) infection; LIHC cis rs11792861 0.926 rs7855282 chr9:111802614 T/A cg13535736 chr9:111863775 C9orf5 -0.42 -6.42 -0.33 4.48e-10 Menarche (age at onset); LIHC cis rs7503168 0.558 rs11870472 chr17:33872649 G/A cg05299278 chr17:33885742 SLFN14 -0.29 -6.0 -0.31 5.09e-9 Plateletcrit; LIHC cis rs7937890 0.967 rs963212 chr11:14324732 A/G cg22961513 chr11:14280813 SPON1 0.47 7.2 0.36 3.8e-12 Mitochondrial DNA levels; LIHC cis rs4927850 0.501 rs9881504 chr3:195656614 A/G cg22809023 chr3:195622598 TNK2 0.42 5.74 0.3 2.14e-8 Pancreatic cancer; LIHC cis rs919433 1.000 rs1346649 chr2:198166117 C/A cg10820045 chr2:198174542 NA -0.62 -10.85 -0.51 8.91e-24 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9916302 0.706 rs11655972 chr17:37407072 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -12.18 -0.55 1.42e-28 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg08280861 chr8:58055591 NA 0.51 6.19 0.32 1.7e-9 Developmental language disorder (linguistic errors); LIHC cis rs10540 1.000 rs61876335 chr11:488878 T/C cg03352830 chr11:487213 PTDSS2 0.66 5.74 0.3 2.11e-8 Body mass index; LIHC cis rs244731 0.959 rs7721671 chr5:176630984 A/G cg16006841 chr5:176797999 RGS14 -0.6 -5.95 -0.31 6.69e-9 Urate levels in lean individuals; LIHC cis rs477895 0.713 rs67546972 chr11:63962162 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 9.65 0.46 1.17e-19 Mean platelet volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17422427 chr2:241507521 RNPEPL1 0.4 6.9 0.35 2.56e-11 Cognitive function; LIHC cis rs5756931 0.503 rs2012725 chr22:38536861 C/G cg25457927 chr22:38595422 NA -0.26 -6.43 -0.33 4.23e-10 Triglycerides; LIHC trans rs11039798 1.000 rs7102865 chr11:48458361 A/C cg15704280 chr7:45808275 SEPT13 0.62 6.29 0.32 9.87e-10 Axial length; LIHC cis rs2404602 0.647 rs10851889 chr15:77023336 C/T cg03037974 chr15:76606532 NA -0.61 -10.28 -0.49 8.59e-22 Blood metabolite levels; LIHC cis rs12824058 0.737 rs2398508 chr12:130816460 G/A cg24229701 chr12:130821962 PIWIL1 0.45 6.74 0.34 6.91e-11 Menopause (age at onset); LIHC cis rs1153858 1.000 rs9783731 chr15:45642884 C/T cg26924012 chr15:45694286 SPATA5L1 -0.88 -16.9 -0.67 5.15e-47 Homoarginine levels; LIHC cis rs864537 0.646 rs1773542 chr1:167432949 T/C cg22356347 chr1:167427500 CD247 -0.34 -5.81 -0.3 1.45e-8 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs10792665 0.934 rs4114984 chr11:82672616 C/A cg24227371 chr11:82718527 RAB30 -0.32 -7.57 -0.38 3.53e-13 Obesity-related traits; LIHC cis rs9399135 0.967 rs9376075 chr6:135296963 A/G cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.36e-11 Red blood cell count; LIHC cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3106136 0.872 rs2016476 chr4:95229004 G/A cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.5 -0.38 5.59e-13 Capecitabine sensitivity; LIHC cis rs7412746 0.611 rs66847267 chr1:150875173 C/A cg18016565 chr1:150552671 MCL1 0.49 9.43 0.45 6.57e-19 Melanoma; LIHC cis rs4650994 0.593 rs10798618 chr1:178519124 A/C cg05350800 chr1:178550844 NA -0.35 -7.59 -0.38 2.98e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg21724239 chr8:58056113 NA 0.51 7.32 0.37 1.81e-12 Developmental language disorder (linguistic errors); LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg26338869 chr17:61819248 STRADA 0.53 7.14 0.36 5.6e-12 Height; LIHC trans rs61931739 0.534 rs7138522 chr12:34039762 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.82 0.35 4.04e-11 Morning vs. evening chronotype; LIHC cis rs1728785 0.818 rs1069289 chr16:68585317 C/A cg02972257 chr16:68554789 NA -0.57 -6.41 -0.33 4.84e-10 Ulcerative colitis; LIHC cis rs769267 0.965 rs4808937 chr19:19398005 A/G cg21559469 chr19:19431446 KIAA0892;SF4 0.41 5.74 0.3 2.09e-8 Tonsillectomy; LIHC cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.13e-9 Menopause (age at onset); LIHC cis rs7107174 1.000 rs2512537 chr11:77971947 T/C cg02023728 chr11:77925099 USP35 0.5 9.51 0.46 3.41e-19 Testicular germ cell tumor; LIHC cis rs66569888 0.789 rs66826026 chr2:106732879 C/T cg16099169 chr2:106886729 NA -0.83 -8.84 -0.43 5.26e-17 Facial morphology (factor 23); LIHC cis rs77633900 0.772 rs2956873 chr15:76695305 G/A cg21673338 chr15:77095150 SCAPER -0.51 -5.88 -0.3 9.53e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs9311474 0.607 rs4475032 chr3:52560021 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.43 5.87 0.3 1.04e-8 Electroencephalogram traits; LIHC trans rs12752401 0.867 rs34777937 chr1:103036317 C/A cg03332897 chr19:740442 PALM 0.46 6.11 0.31 2.68e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs748404 0.723 rs512431 chr15:43541939 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.47 -8.28 -0.41 2.86e-15 Lung cancer; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.512 rs5758465 chr22:42175314 T/C cg06634786 chr22:41940651 POLR3H 0.69 6.91 0.35 2.44e-11 Vitiligo; LIHC cis rs7762018 0.943 rs7772889 chr6:170142458 T/C cg19338460 chr6:170058176 WDR27 -0.37 -5.72 -0.3 2.28e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs12620999 1.000 rs10803655 chr2:238075551 C/T cg23555395 chr2:238036564 NA -0.31 -5.84 -0.3 1.22e-8 Systemic lupus erythematosus; LIHC cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg08859206 chr1:53392774 SCP2 0.46 7.4 0.37 1.09e-12 Monocyte count; LIHC cis rs523522 0.962 rs4767903 chr12:120930046 G/A cg27279351 chr12:120934652 DYNLL1 0.67 12.06 0.55 3.77e-28 High light scatter reticulocyte count; LIHC cis rs11958404 0.932 rs55943686 chr5:157439591 G/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs8017423 0.904 rs12433417 chr14:90804028 A/G cg04374321 chr14:90722782 PSMC1 -0.71 -12.78 -0.57 7.49e-31 Mortality in heart failure; LIHC cis rs7592578 0.882 rs61117285 chr2:191468986 G/C cg27211696 chr2:191398769 TMEM194B -0.61 -7.73 -0.39 1.17e-13 Diastolic blood pressure; LIHC cis rs7312933 1.000 rs12372597 chr12:42412850 C/T cg01256987 chr12:42539512 GXYLT1 -0.39 -6.53 -0.33 2.38e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs2832191 0.716 rs2297252 chr21:30377104 G/A cg14791747 chr16:20752902 THUMPD1 -0.47 -6.69 -0.34 9.08e-11 Dental caries; LIHC trans rs2579103 0.729 rs1344964 chr12:90670653 C/A cg00091569 chr3:40428383 ENTPD3 0.39 6.17 0.32 1.94e-9 Body mass index; LIHC cis rs6448317 0.556 rs4481227 chr4:24906858 C/T cg21108841 chr4:24914750 CCDC149 0.53 6.57 0.33 1.92e-10 Heschl's gyrus morphology; LIHC cis rs7903847 0.620 rs10882907 chr10:99125788 C/G cg20016023 chr10:99160130 RRP12 0.37 5.81 0.3 1.44e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg03806693 chr22:41940476 POLR3H 1.12 13.03 0.58 8.92e-32 Vitiligo; LIHC cis rs7264396 0.563 rs17092980 chr20:34289005 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.5 -0.42 6.02e-16 Total cholesterol levels; LIHC cis rs853679 0.517 rs9283884 chr6:28135660 C/G cg16479474 chr6:28041457 NA -0.46 -6.42 -0.33 4.46e-10 Depression; LIHC cis rs56011263 0.687 rs11734460 chr4:705074 C/T cg20735989 chr4:730612 PCGF3 -0.66 -8.76 -0.43 8.91e-17 White blood cell count; LIHC cis rs6430585 0.528 rs895285 chr2:136710554 A/G cg07169764 chr2:136633963 MCM6 1.29 21.31 0.76 1.03e-64 Corneal structure; LIHC cis rs6733011 0.578 rs6714243 chr2:99510039 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.45 -6.46 -0.33 3.53e-10 Bipolar disorder; LIHC cis rs4423214 1.000 rs12797951 chr11:71143266 G/T cg05163923 chr11:71159392 DHCR7 -0.92 -14.62 -0.62 6.11e-38 Vitamin D levels; LIHC cis rs9467773 0.933 rs2024970 chr6:26497520 T/A cg09904177 chr6:26538194 HMGN4 0.56 10.72 0.5 2.51e-23 Intelligence (multi-trait analysis); LIHC cis rs4660306 0.677 rs10493120 chr1:45903488 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.66 6.73 0.34 6.96e-11 Homocysteine levels; LIHC cis rs847851 0.617 rs9380478 chr6:34960811 A/T cg13137465 chr6:34857473 ANKS1A 0.67 7.53 0.38 4.57e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs4237845 0.788 rs1962047 chr12:58292707 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.45 6.33 0.32 7.68e-10 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12661088 chr5:43120934 ZNF131 0.44 6.65 0.34 1.13e-10 Pancreatic cancer; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs6519955 0.897 rs4073601 chr22:46434686 A/G cg05468064 chr22:46423449 NA 0.36 5.79 0.3 1.57e-8 Dupuytren's disease; LIHC cis rs6669384 0.774 rs7550821 chr1:208029947 C/T cg22525895 chr1:207977042 MIR29B2 -0.49 -6.13 -0.31 2.4e-9 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs2303759 0.881 rs10412811 chr19:49884495 G/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.88 0.43 3.98e-17 Multiple sclerosis; LIHC cis rs1005277 0.579 rs2474567 chr10:38382492 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2710642 0.721 rs58305080 chr2:62895132 C/T cg17519650 chr2:63277830 OTX1 0.53 7.82 0.39 6.46e-14 LDL cholesterol levels;LDL cholesterol; LIHC cis rs6450176 0.909 rs12659966 chr5:53292892 C/G ch.5.1024479R chr5:53302184 ARL15 0.8 14.53 0.62 1.4e-37 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs9733 0.519 rs72704603 chr1:150707992 C/T cg18016565 chr1:150552671 MCL1 0.59 11.39 0.52 1.06e-25 Tonsillectomy; LIHC trans rs11039798 0.588 rs10838979 chr11:48626810 T/G cg15704280 chr7:45808275 SEPT13 0.57 6.41 0.33 4.77e-10 Axial length; LIHC cis rs523522 0.926 rs10849766 chr12:121025894 G/A cg12219531 chr12:120966889 COQ5 0.68 13.18 0.58 2.41e-32 High light scatter reticulocyte count; LIHC cis rs8067545 0.586 rs57837691 chr17:20203073 T/C cg13482628 chr17:19912719 NA -0.41 -6.69 -0.34 9.33e-11 Schizophrenia; LIHC cis rs611744 0.967 rs475865 chr8:109235858 G/C cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs11626933 1.000 rs45463097 chr14:90744188 G/A cg04374321 chr14:90722782 PSMC1 0.48 6.53 0.33 2.34e-10 Gut microbiota (bacterial taxa); LIHC cis rs9660992 0.674 rs1151784 chr1:205232447 C/T cg21545522 chr1:205238299 TMCC2 0.43 8.15 0.4 7.01e-15 Mean corpuscular volume;Mean platelet volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24809768 chr5:167914047 RARS 0.48 7.26 0.37 2.58e-12 Cognitive function; LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.95 20.05 0.74 1.12e-59 Height; LIHC cis rs911555 0.655 rs10149470 chr14:104017953 A/G cg24130564 chr14:104152367 KLC1 -0.44 -7.34 -0.37 1.62e-12 Intelligence (multi-trait analysis); LIHC cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg13271783 chr10:134563150 INPP5A -0.57 -6.61 -0.34 1.44e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg11644478 chr21:40555479 PSMG1 -0.39 -6.0 -0.31 4.94e-9 Cognitive function; LIHC cis rs9303280 0.901 rs2305479 chr17:38062217 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.75 0.3 2e-8 Self-reported allergy; LIHC cis rs59901009 0.954 rs55893317 chr11:10180991 A/G cg01453529 chr11:10209919 SBF2 -0.31 -6.04 -0.31 4.1e-9 Hematocrit;Hemoglobin concentration; LIHC cis rs7512552 0.839 rs834236 chr1:150362968 C/T cg15654264 chr1:150340011 RPRD2 0.68 11.27 0.52 2.96e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs11098499 0.954 rs59394118 chr4:120295551 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.64 0.42 2.27e-16 Corneal astigmatism; LIHC cis rs10744422 0.925 rs2292132 chr12:123332834 T/C cg18912006 chr12:123335444 HIP1R -0.63 -7.64 -0.38 2.14e-13 Schizophrenia; LIHC cis rs910316 0.967 rs175479 chr14:75561871 A/C cg08847533 chr14:75593920 NEK9 -0.9 -19.96 -0.73 2.68e-59 Height; LIHC cis rs8177253 1.000 rs8177253 chr3:133480192 A/G cg12373951 chr3:133503437 NA -0.69 -12.28 -0.55 5.55e-29 Iron status biomarkers; LIHC cis rs273218 0.573 rs10513033 chr5:53333477 T/C ch.5.1024479R chr5:53302184 ARL15 -0.86 -15.33 -0.64 9.9e-41 Migraine; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07991241 chr10:33269695 NA 0.51 7.91 0.39 3.54e-14 Pancreatic cancer; LIHC cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6546550 0.901 rs7573442 chr2:70154037 G/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.63 -0.38 2.31e-13 Prevalent atrial fibrillation; LIHC cis rs9921222 0.500 rs11648673 chr16:377794 G/A cg12437481 chr16:420112 MRPL28 -0.65 -8.73 -0.43 1.15e-16 Bone mineral density (spine);Bone mineral density; LIHC cis rs35110281 0.633 rs762400 chr21:45113629 C/G cg04455712 chr21:45112962 RRP1B -0.51 -8.88 -0.43 3.81e-17 Mean corpuscular volume; LIHC cis rs4934494 0.768 rs17125834 chr10:91433162 G/A cg19698084 chr10:91461284 KIF20B -0.49 -6.49 -0.33 2.93e-10 Red blood cell count; LIHC cis rs4713118 0.911 rs9295746 chr6:27730064 T/C cg20933634 chr6:27740509 NA 0.49 6.4 0.33 5.26e-10 Parkinson's disease; LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg03874509 chr1:107600012 PRMT6 0.76 12.17 0.55 1.44e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7927771 1.000 rs4752856 chr11:47648042 C/T cg20135002 chr11:47629003 NA -0.58 -10.04 -0.48 5.83e-21 Subjective well-being; LIHC cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg10802521 chr3:52805072 NEK4 -0.44 -7.36 -0.37 1.35e-12 Bipolar disorder; LIHC cis rs11971779 0.616 rs6967932 chr7:139022381 C/T cg07862535 chr7:139043722 LUC7L2 0.58 9.92 0.47 1.53e-20 Diisocyanate-induced asthma; LIHC cis rs4237845 0.514 rs4760339 chr12:58268149 G/T cg04478727 chr12:58166393 METTL1;FAM119B 0.58 8.07 0.4 1.23e-14 Intelligence (multi-trait analysis); LIHC trans rs3960554 0.741 rs10232162 chr7:75702505 C/T cg19862616 chr7:65841803 NCRNA00174 0.61 8.52 0.42 5.19e-16 Eotaxin levels; LIHC cis rs597539 0.690 rs608810 chr11:68624118 G/C cg04772025 chr11:68637568 NA 0.45 5.77 0.3 1.82e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9296092 0.538 rs62405948 chr6:33522753 A/C cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00166836 chr6:149721425 MAP3K7IP2;SUMO4 0.42 6.06 0.31 3.67e-9 Pancreatic cancer; LIHC cis rs17685 0.712 rs60232511 chr7:75800082 A/G cg04610667 chr7:75704037 NA -0.35 -6.18 -0.32 1.86e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7131987 0.903 rs7974221 chr12:29399448 A/G cg12903224 chr12:29470962 FAR2 -0.39 -6.28 -0.32 1.02e-9 QT interval; LIHC cis rs7572733 0.534 rs700672 chr2:198691455 G/A cg00792783 chr2:198669748 PLCL1 0.46 6.82 0.35 4.1e-11 Dermatomyositis; LIHC cis rs868036 0.718 rs28399056 chr15:68116010 C/A cg24579218 chr15:68104479 NA -0.33 -5.73 -0.3 2.18e-8 Restless legs syndrome; LIHC cis rs1707322 0.721 rs4431884 chr1:46101323 C/T cg03146154 chr1:46216737 IPP 0.57 9.96 0.47 1.13e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9902453 0.765 rs2127001 chr17:28098219 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.75 -0.6 1.56e-34 Coffee consumption (cups per day); LIHC cis rs2230307 0.536 rs11166384 chr1:100439890 C/T cg24955406 chr1:100503596 HIAT1 0.6 6.01 0.31 4.64e-9 Carotid intima media thickness; LIHC cis rs9381040 0.610 rs9367094 chr6:41017860 T/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.26 -0.32 1.12e-9 Alzheimer's disease (late onset); LIHC cis rs9916302 0.904 rs602688 chr17:37439496 C/T cg00129232 chr17:37814104 STARD3 -0.36 -5.84 -0.3 1.23e-8 Glomerular filtration rate (creatinine); LIHC trans rs2262909 0.962 rs11673195 chr19:22313814 T/C cg05197062 chr11:11642011 GALNTL4 0.46 6.72 0.34 7.6e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs7208859 0.573 rs58920731 chr17:29191746 G/T cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.88 0.54 1.69e-27 Prudent dietary pattern; LIHC cis rs11792861 0.926 rs75128146 chr9:111833791 G/T cg13535736 chr9:111863775 C9orf5 -0.39 -5.94 -0.31 7.12e-9 Menarche (age at onset); LIHC cis rs10463316 0.894 rs11167542 chr5:150760282 A/G cg03212797 chr5:150827313 SLC36A1 0.43 6.53 0.33 2.34e-10 Metabolite levels (Pyroglutamine); LIHC trans rs3857536 0.605 rs36040831 chr6:66876588 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.55 -8.45 -0.42 8.33e-16 Blood trace element (Cu levels); LIHC cis rs4699052 0.507 rs10005997 chr4:104301711 C/G cg16532752 chr4:104119610 CENPE -0.46 -6.5 -0.33 2.81e-10 Testicular germ cell tumor; LIHC cis rs2010672 0.500 rs9888660 chr15:91160768 C/T cg26821196 chr15:91095069 CRTC3 0.35 6.28 0.32 1.01e-9 Sum eosinophil basophil counts;Eosinophil percentage of white cells;Eosinophil counts; LIHC cis rs72627123 0.867 rs3815331 chr14:74482948 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 5.82 0.3 1.35e-8 Morning vs. evening chronotype; LIHC cis rs9858542 0.951 rs1800668 chr3:49395757 G/A cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs782590 0.557 rs7592219 chr2:55887176 T/C cg18811423 chr2:55921094 PNPT1 -0.51 -7.62 -0.38 2.55e-13 Metabolic syndrome; LIHC cis rs72781680 0.898 rs2339851 chr2:23938883 G/A cg08917208 chr2:24149416 ATAD2B 0.96 8.22 0.41 4.3e-15 Lymphocyte counts; LIHC cis rs9611565 0.512 rs5758465 chr22:42175314 T/C cg03806693 chr22:41940476 POLR3H 0.95 9.86 0.47 2.37e-20 Vitiligo; LIHC cis rs2197308 0.765 rs12370231 chr12:37917881 T/C cg26384229 chr12:38710491 ALG10B 0.85 10.39 0.49 3.59e-22 Morning vs. evening chronotype; LIHC cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs2239547 0.603 rs9870898 chr3:53092375 A/G cg11645453 chr3:52864694 ITIH4 0.29 7.09 0.36 7.62e-12 Schizophrenia; LIHC cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg08888203 chr3:10149979 C3orf24 0.54 6.27 0.32 1.06e-9 Alzheimer's disease; LIHC cis rs9916302 0.706 rs7503377 chr17:37708841 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -11.45 -0.53 6.64e-26 Glomerular filtration rate (creatinine); LIHC cis rs77669868 0.640 rs2073848 chr11:114051904 A/G cg01914181 chr11:114070210 ZBTB16 0.54 7.06 0.36 9.31e-12 Monocyte percentage of white cells; LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.4 0.33 5e-10 Renal cell carcinoma; LIHC cis rs10751667 0.666 rs7934963 chr11:957220 C/T cg06064525 chr11:970664 AP2A2 -0.56 -14.96 -0.63 2.86e-39 Alzheimer's disease (late onset); LIHC cis rs12477438 0.520 rs1044575 chr2:99812070 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.25 0.64 1.91e-40 Chronic sinus infection; LIHC cis rs10876993 0.890 rs1678539 chr12:58060359 A/G cg18357645 chr12:58087776 OS9 0.52 8.57 0.42 3.68e-16 Celiac disease or Rheumatoid arthritis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09514589 chr15:76603992 ETFA 0.45 6.18 0.32 1.8e-9 Pancreatic cancer; LIHC cis rs249954 0.512 rs171617 chr16:23694774 A/T cg09867953 chr16:23706666 ERN2 0.35 5.96 0.31 6.16e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2404602 0.574 rs4886795 chr15:76642218 G/C cg23625390 chr15:77176239 SCAPER -0.38 -6.03 -0.31 4.18e-9 Blood metabolite levels; LIHC cis rs735396 1.000 rs1169313 chr12:121442670 C/T cg25281562 chr12:121454272 C12orf43 -0.33 -5.76 -0.3 1.91e-8 N-glycan levels; LIHC trans rs7777484 0.534 rs2533886 chr7:2834869 C/T cg18070394 chr4:2470786 RNF4 0.39 6.06 0.31 3.51e-9 Height; LIHC cis rs3806843 1.000 rs6870764 chr5:140171790 C/T cg26395211 chr5:140044315 WDR55 -0.43 -6.43 -0.33 4.19e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs929354 0.629 rs6950739 chr7:156982450 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.79 0.3 1.62e-8 Body mass index; LIHC cis rs4595586 0.545 rs1319791 chr12:39372486 G/T cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs600806 0.850 rs3879452 chr1:109929237 G/A cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs28830936 0.966 rs890498 chr15:42111298 C/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.0 -0.31 4.98e-9 Diastolic blood pressure; LIHC trans rs877282 0.945 rs11253398 chr10:790012 T/C cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs3806843 1.000 rs3822346 chr5:140187322 C/T cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs3806843 1.000 rs3733707 chr5:140181892 T/C cg19875535 chr5:140030758 IK 0.37 5.96 0.31 6.29e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs11229555 0.645 rs34054511 chr11:58204943 A/C cg15696309 chr11:58395628 NA -0.65 -7.71 -0.38 1.41e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs3749237 0.595 rs6784820 chr3:49450864 C/T cg02487422 chr3:49467188 NICN1 -0.41 -6.24 -0.32 1.27e-9 Resting heart rate; LIHC cis rs6545883 0.894 rs2694649 chr2:61573826 G/A cg15711740 chr2:61764176 XPO1 0.42 5.74 0.3 2.12e-8 Tuberculosis; LIHC cis rs644148 0.748 rs542150 chr19:44967453 T/C cg15540054 chr19:45004280 ZNF180 0.78 10.72 0.5 2.66e-23 Personality dimensions; LIHC cis rs3770081 1.000 rs12617717 chr2:86342303 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.84 -8.67 -0.42 1.76e-16 Facial emotion recognition (sad faces); LIHC cis rs28374715 0.532 rs316604 chr15:41775221 C/T cg18705301 chr15:41695430 NDUFAF1 -1.25 -18.36 -0.7 6.9e-53 Ulcerative colitis; LIHC cis rs6754311 0.773 rs309125 chr2:136643555 C/T cg17750252 chr2:136567154 LCT -0.35 -6.31 -0.32 8.48e-10 Mosquito bite size; LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg12379764 chr21:47803548 PCNT 0.56 8.42 0.41 1.05e-15 Testicular germ cell tumor; LIHC cis rs9768139 0.708 rs35057023 chr7:158114748 G/A cg25566285 chr7:158114605 PTPRN2 0.22 5.94 0.31 7.2e-9 Calcium levels; LIHC cis rs919433 0.617 rs700645 chr2:198605514 A/G cg03934865 chr2:198174659 NA 0.48 6.91 0.35 2.38e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs459571 0.839 rs10993895 chr9:136887726 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 0.6 9.53 0.46 3.11e-19 Platelet distribution width; LIHC cis rs3762637 0.941 rs7653592 chr3:122218371 G/A cg24169773 chr3:122142474 KPNA1 -0.48 -9.45 -0.46 5.33e-19 LDL cholesterol levels; LIHC cis rs8084351 0.524 rs11082974 chr18:50770171 C/A cg24270629 chr18:50823537 DCC -0.47 -6.89 -0.35 2.65e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg18404041 chr3:52824283 ITIH1 0.59 9.89 0.47 1.91e-20 Electroencephalogram traits; LIHC cis rs7677751 0.806 rs7673984 chr4:55088761 C/T cg17187183 chr4:55093834 PDGFRA 0.66 8.25 0.41 3.4e-15 Corneal astigmatism; LIHC cis rs10791323 0.604 rs2853116 chr11:133707063 A/G cg06766960 chr11:133703094 NA -0.66 -10.83 -0.51 1.04e-23 Childhood ear infection; LIHC cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg18252515 chr7:66147081 NA -1.3 -16.86 -0.67 7.26e-47 Diabetic kidney disease; LIHC cis rs4319547 0.695 rs7969429 chr12:122875606 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.28 -0.37 2.3e-12 Body mass index; LIHC cis rs7208859 0.623 rs9894709 chr17:29078454 G/A cg14067834 chr17:29058358 SUZ12P 0.68 6.69 0.34 9.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9814567 1.000 rs10935120 chr3:134233092 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.67 12.49 0.56 9.07e-30 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs17102423 0.661 rs45604339 chr14:65543102 C/T cg11161011 chr14:65562177 MAX -0.53 -7.34 -0.37 1.6e-12 Obesity-related traits; LIHC cis rs4919087 1.000 rs10786326 chr10:99070377 G/A cg25902810 chr10:99078978 FRAT1 0.7 10.9 0.51 6.1e-24 Monocyte count; LIHC trans rs1814175 0.654 rs1164676 chr11:49324868 T/C cg15704280 chr7:45808275 SEPT13 0.83 14.84 0.63 8.54e-39 Height; LIHC cis rs7772486 0.817 rs12198065 chr6:146385286 G/C cg13319975 chr6:146136371 FBXO30 -0.38 -6.26 -0.32 1.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6089829 0.926 rs6062395 chr20:61667904 A/G cg03213289 chr20:61660250 NA 0.51 9.01 0.44 1.48e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs9911578 0.967 rs1588322 chr17:56990099 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs4853012 0.941 rs2421752 chr2:74341615 A/G cg20891558 chr2:74357851 NA 0.81 16.46 0.66 3e-45 Gestational age at birth (maternal effect); LIHC cis rs7937682 0.883 rs553632 chr11:111462897 C/T cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs9611519 0.929 rs4821991 chr22:41440683 T/C cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.13e-14 Neuroticism; LIHC cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg08975724 chr8:8085496 FLJ10661 -0.39 -6.55 -0.33 2.12e-10 Neuroticism; LIHC cis rs875971 0.862 rs801204 chr7:66022921 T/C cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC trans rs11098499 0.955 rs56386062 chr4:120155135 T/C cg25214090 chr10:38739885 LOC399744 0.54 8.2 0.41 4.76e-15 Corneal astigmatism; LIHC cis rs853679 0.517 rs6932109 chr6:28078303 A/G cg16479474 chr6:28041457 NA -0.46 -6.58 -0.34 1.77e-10 Depression; LIHC cis rs798554 0.679 rs1636249 chr7:2884283 T/G cg13628971 chr7:2884303 GNA12 0.6 10.38 0.49 4.01e-22 Height; LIHC cis rs1728785 0.786 rs1728770 chr16:68564124 G/C cg02972257 chr16:68554789 NA -0.56 -6.34 -0.32 7.15e-10 Ulcerative colitis; LIHC cis rs9303280 0.806 rs4795395 chr17:37962987 T/A cg11212589 chr17:38028394 ZPBP2 0.32 6.44 0.33 4.06e-10 Self-reported allergy; LIHC cis rs16958440 0.581 rs11875768 chr18:44689360 T/G cg17192377 chr18:44677553 HDHD2 0.71 7.79 0.39 8.32e-14 Sitting height ratio; LIHC cis rs9326248 0.539 rs7120565 chr11:117042949 T/C cg01368799 chr11:117014884 PAFAH1B2 0.67 10.3 0.49 7.28e-22 Blood protein levels; LIHC cis rs10791097 0.694 rs4436551 chr11:130755739 A/G cg14779329 chr11:130786720 SNX19 -0.41 -6.26 -0.32 1.17e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2073300 0.609 rs74273791 chr20:23418067 A/T cg12062639 chr20:23401060 NAPB 1.04 13.41 0.59 2.97e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs12291225 0.585 rs11023194 chr11:14369769 T/C cg19336497 chr11:14380999 RRAS2 -0.67 -14.14 -0.61 4.54e-36 Sense of smell; LIHC cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.63 0.38 2.39e-13 Bipolar disorder; LIHC cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg04352962 chr1:209979756 IRF6 0.4 6.2 0.32 1.63e-9 Cleft lip with or without cleft palate; LIHC cis rs4919694 1.000 rs35159404 chr10:104805610 C/A cg04362960 chr10:104952993 NT5C2 1.14 8.87 0.43 4.02e-17 Arsenic metabolism; LIHC cis rs5758511 0.680 rs56111723 chr22:42664883 T/A cg20195005 chr22:42527684 CYP2D6 0.31 5.88 0.3 9.59e-9 Birth weight; LIHC cis rs6598163 0.517 rs11246827 chr12:132296423 G/A cg10319629 chr12:132285459 NA 0.46 8.04 0.4 1.47e-14 Migraine; LIHC cis rs10751667 0.600 rs7394783 chr11:1005108 C/T cg20946044 chr11:1010712 AP2A2 0.34 5.98 0.31 5.67e-9 Alzheimer's disease (late onset); LIHC cis rs3770081 1.000 rs3731819 chr2:86368641 C/A cg01119172 chr2:86362222 SNORD94;PTCD3 0.44 6.06 0.31 3.59e-9 Facial emotion recognition (sad faces); LIHC cis rs2842992 0.830 rs2758352 chr6:160122921 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.6 0.56 3.52e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs11583043 1.000 rs17123612 chr1:101476814 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.71 0.43 1.35e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18842717 chr11:3400387 ZNF195 0.48 6.86 0.35 3.32e-11 Lung function (FEV1/FVC); LIHC cis rs2280018 0.963 rs4985147 chr16:15168760 T/C cg07549590 chr16:15018862 NA -0.34 -6.41 -0.33 4.91e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs600806 0.888 rs680434 chr1:109842271 C/T cg16275483 chr1:110013120 SYPL2 -0.5 -6.09 -0.31 3.09e-9 Intelligence (multi-trait analysis); LIHC cis rs6604026 0.555 rs56044027 chr1:93082694 C/T cg13858687 chr1:93297071 RPL5 0.6 5.71 0.3 2.41e-8 Multiple sclerosis; LIHC cis rs2243480 1.000 rs160643 chr7:65558222 C/T cg12463550 chr7:65579703 CRCP 0.6 6.63 0.34 1.29e-10 Diabetic kidney disease; LIHC cis rs6912958 0.535 rs242283 chr6:88030931 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.65 0.53 1.16e-26 Monocyte percentage of white cells; LIHC cis rs7618501 0.521 rs11709573 chr3:49956628 C/T cg05623727 chr3:50126028 RBM5 0.34 5.77 0.3 1.8e-8 Intelligence (multi-trait analysis); LIHC cis rs11764590 0.694 rs60626033 chr7:2099719 A/G cg23043544 chr7:2124092 MAD1L1 -0.41 -6.61 -0.34 1.49e-10 Neuroticism; LIHC cis rs11677370 0.561 rs13003140 chr2:3816759 G/T cg17052675 chr2:3827356 NA -0.56 -7.22 -0.36 3.39e-12 Type 2 diabetes; LIHC cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg23205692 chr1:25664452 TMEM50A 0.37 6.01 0.31 4.67e-9 Erythrocyte sedimentation rate; LIHC cis rs9902453 1.000 rs4350617 chr17:28423088 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.62 9.47 0.46 4.62e-19 Coffee consumption (cups per day); LIHC trans rs1814175 0.645 rs1722000 chr11:49917928 A/C cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs4713118 0.586 rs9468290 chr6:28087674 C/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Parkinson's disease; LIHC cis rs6546550 0.867 rs726920 chr2:70152027 G/C cg02498382 chr2:70120550 SNRNP27 -0.44 -7.62 -0.38 2.56e-13 Prevalent atrial fibrillation; LIHC cis rs11122272 0.735 rs2486746 chr1:231497324 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.05 -0.51 1.78e-24 Hemoglobin concentration; LIHC cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.81 8.03 0.4 1.63e-14 Platelet count; LIHC cis rs9611519 0.894 rs9611486 chr22:41458784 C/G cg06634786 chr22:41940651 POLR3H -0.52 -5.73 -0.3 2.26e-8 Neuroticism; LIHC cis rs875971 1.000 rs7789768 chr7:65938980 A/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs963731 0.737 rs10194374 chr2:39244914 G/A cg04010122 chr2:39346883 SOS1 -0.68 -5.86 -0.3 1.1e-8 Corticobasal degeneration; LIHC cis rs8005677 0.962 rs10130756 chr14:23396600 C/G cg07971674 chr14:23388846 RBM23 -0.4 -5.76 -0.3 1.92e-8 Cognitive ability (multi-trait analysis); LIHC cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg01788221 chr16:89496183 ANKRD11 -0.39 -6.33 -0.32 7.52e-10 Multiple myeloma (IgH translocation); LIHC cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg04267008 chr7:1944627 MAD1L1 -0.62 -9.89 -0.47 1.91e-20 Bipolar disorder and schizophrenia; LIHC cis rs1577917 0.958 rs72907388 chr6:86440207 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.39 -0.37 1.14e-12 Response to antipsychotic treatment; LIHC cis rs172166 0.694 rs1225716 chr6:28113746 A/C cg25329415 chr6:28076851 NA 0.27 5.81 0.3 1.46e-8 Cardiac Troponin-T levels; LIHC cis rs4665809 0.941 rs1470096 chr2:26311482 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.39 -0.45 8.63e-19 Gut microbiome composition (summer); LIHC cis rs11764590 0.694 rs7801349 chr7:2085553 T/C cg23422044 chr7:1970798 MAD1L1 -0.5 -7.88 -0.39 4.53e-14 Neuroticism; LIHC cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs2404602 0.608 rs12439484 chr15:76602937 A/C cg22467129 chr15:76604101 ETFA -0.37 -6.08 -0.31 3.18e-9 Blood metabolite levels; LIHC cis rs11608355 0.545 rs7969313 chr12:109907303 A/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs12477438 0.520 rs11685759 chr2:99766217 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg05368731 chr17:41323189 NBR1 0.73 12.67 0.57 1.94e-30 Menopause (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20753294 chr5:142782791 NR3C1 -0.47 -6.49 -0.33 3.03e-10 Longevity; LIHC cis rs4742903 0.935 rs3818626 chr9:106856633 C/T cg14250997 chr9:106856677 SMC2 0.43 7.36 0.37 1.36e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs3818285 0.632 rs536343 chr10:111632879 T/C cg00817464 chr10:111662876 XPNPEP1 0.66 11.47 0.53 5.36e-26 Superior crus of antihelix expression; LIHC trans rs561341 1.000 rs55643307 chr17:30263074 T/C cg20587970 chr11:113659929 NA -1.46 -11.62 -0.53 1.61e-26 Hip circumference adjusted for BMI; LIHC cis rs875971 0.862 rs6944374 chr7:65686929 C/G cg11764359 chr7:65958608 NA -0.74 -12.35 -0.56 3.04e-29 Aortic root size; LIHC cis rs1775715 0.870 rs1251407 chr10:32238325 A/G cg14930904 chr10:32216787 ARHGAP12 0.39 6.96 0.35 1.76e-11 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs3812049 0.737 rs1112956 chr5:127433798 C/T cg16011800 chr17:1958478 HIC1 0.47 6.9 0.35 2.56e-11 Lymphocyte counts;Red cell distribution width; LIHC cis rs829883 0.664 rs829876 chr12:98842138 A/G cg25150519 chr12:98850993 NA 0.68 10.72 0.5 2.61e-23 Colorectal adenoma (advanced); LIHC trans rs1814175 0.817 rs11493756 chr11:50017885 T/C cg03929089 chr4:120376271 NA -0.89 -18.71 -0.71 2.82e-54 Height; LIHC cis rs6500602 0.702 rs11076835 chr16:4549618 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.47 6.76 0.34 5.98e-11 Schizophrenia; LIHC cis rs67311347 0.911 rs6773917 chr3:40469254 G/T cg09455208 chr3:40491958 NA 0.36 7.33 0.37 1.7e-12 Renal cell carcinoma; LIHC cis rs644799 1.000 rs3748256 chr11:95521953 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 10.01 0.48 7.51e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3823572 0.564 rs2953620 chr7:133666388 T/C cg03336402 chr7:133662267 EXOC4 -0.48 -5.75 -0.3 1.96e-8 Intelligence (multi-trait analysis); LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg22654626 chr19:18699620 C19orf60 -0.46 -6.34 -0.32 7.16e-10 Triglycerides; LIHC cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg08888203 chr3:10149979 C3orf24 0.62 6.93 0.35 2.15e-11 Alzheimer's disease; LIHC cis rs6977660 0.619 rs12534026 chr7:19788687 T/C cg07541023 chr7:19748670 TWISTNB 0.41 6.29 0.32 9.52e-10 Thyroid stimulating hormone; LIHC cis rs4665809 1.000 rs13030858 chr2:26315451 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.99 -0.44 1.69e-17 Gut microbiome composition (summer); LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg09662798 chr17:73498302 CASKIN2 0.5 6.21 0.32 1.53e-9 Mean platelet volume; LIHC cis rs4755351 0.553 rs10836024 chr11:33147564 C/T cg05567920 chr11:33183001 CSTF3 0.42 6.21 0.32 1.56e-9 Lung cancer in ever smokers; LIHC cis rs72781680 0.898 rs72780111 chr2:23991146 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.62 0.38 2.45e-13 Lymphocyte counts; LIHC cis rs66569888 0.507 rs11673736 chr2:106886935 T/C cg00318621 chr2:106887213 NA -0.51 -8.73 -0.43 1.17e-16 Facial morphology (factor 23); LIHC cis rs35110281 0.774 rs2838321 chr21:44995488 A/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.67 -0.34 1.01e-10 Mean corpuscular volume; LIHC cis rs7582180 0.676 rs10048665 chr2:100933085 A/G cg14675211 chr2:100938903 LONRF2 0.56 8.69 0.43 1.5e-16 Intelligence (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg22926252 chr12:14956350 WBP11;C12orf60 0.42 6.81 0.35 4.29e-11 Calcium levels; LIHC cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg11861562 chr11:117069780 TAGLN 0.47 7.81 0.39 7.29e-14 Blood protein levels; LIHC cis rs13161895 1.000 rs34027780 chr5:179478891 C/A cg02702477 chr5:179499311 RNF130 0.81 11.28 0.52 2.69e-25 LDL cholesterol; LIHC trans rs61931739 0.534 rs4086956 chr12:34105047 A/T cg26384229 chr12:38710491 ALG10B 0.49 6.9 0.35 2.55e-11 Morning vs. evening chronotype; LIHC cis rs3096299 0.935 rs3114890 chr16:89449546 C/G cg08822215 chr16:89438651 ANKRD11 -0.48 -7.46 -0.37 7.11e-13 Multiple myeloma (IgH translocation); LIHC cis rs2072499 0.966 rs2842882 chr1:156165342 T/G cg25208724 chr1:156163844 SLC25A44 0.94 15.98 0.65 2.44e-43 Testicular germ cell tumor; LIHC trans rs7937682 0.961 rs4936682 chr11:111629743 T/G cg18187862 chr3:45730750 SACM1L -0.56 -6.42 -0.33 4.64e-10 Primary sclerosing cholangitis; LIHC cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg10802521 chr3:52805072 NEK4 0.45 7.31 0.37 1.87e-12 Bipolar disorder; LIHC cis rs3853824 0.965 rs7217601 chr17:54904121 A/G cg13675837 chr17:54910204 DGKE 0.41 5.9 0.3 8.85e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2230307 0.536 rs575971 chr1:100546591 T/C cg24955406 chr1:100503596 HIAT1 0.61 6.06 0.31 3.51e-9 Carotid intima media thickness; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21504918 chr5:150400001 GPX3 0.4 6.94 0.35 1.92e-11 Cognitive function; LIHC cis rs514406 0.679 rs541852 chr1:53256834 A/G cg27535305 chr1:53392650 SCP2 0.32 6.32 0.32 8.07e-10 Monocyte count; LIHC cis rs10870270 0.830 rs10781571 chr10:133774316 G/C cg08754478 chr10:133766260 PPP2R2D -0.53 -7.79 -0.39 7.89e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs3768617 0.811 rs4396114 chr1:183007441 C/T ch.1.3577855R chr1:183094577 LAMC1 0.48 7.61 0.38 2.64e-13 Fuchs's corneal dystrophy; LIHC cis rs10751667 0.643 rs10902238 chr11:944810 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.87 -0.63 6.47e-39 Alzheimer's disease (late onset); LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.8 0.39 7.36e-14 Prudent dietary pattern; LIHC cis rs1580019 0.563 rs2392071 chr7:32572536 G/A cg14728415 chr7:32535168 LSM5;AVL9 0.42 6.0 0.31 4.95e-9 Cognitive ability; LIHC cis rs12497850 0.864 rs6779394 chr3:49157771 G/A cg07636037 chr3:49044803 WDR6 0.88 14.99 0.63 2.11e-39 Parkinson's disease; LIHC cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg18279126 chr7:2041391 MAD1L1 0.36 5.89 0.3 9.29e-9 Bipolar disorder and schizophrenia; LIHC cis rs72781680 0.611 rs7602797 chr2:24318148 C/T cg06627628 chr2:24431161 ITSN2 -0.65 -7.6 -0.38 2.84e-13 Lymphocyte counts; LIHC cis rs1371867 0.555 rs2861348 chr8:101285074 A/G cg06002616 chr8:101225028 SPAG1 -0.35 -5.76 -0.3 1.85e-8 Atrioventricular conduction; LIHC cis rs7937682 0.883 rs486038 chr11:111465963 A/C cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC trans rs875971 0.545 rs6970498 chr7:65740895 A/G cg26939375 chr7:64535504 NA 0.41 6.43 0.33 4.31e-10 Aortic root size; LIHC cis rs981946 0.570 rs6917778 chr6:3358935 G/T cg18842474 chr6:3356384 SLC22A23 0.39 6.29 0.32 9.68e-10 Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN); LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg06873352 chr17:61820015 STRADA -0.71 -12.42 -0.56 1.78e-29 Prudent dietary pattern; LIHC cis rs12479064 0.724 rs10496336 chr2:99996165 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -8.71 -0.43 1.35e-16 Chronic sinus infection; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03149313 chr1:226595334 PARP1 -0.42 -6.29 -0.32 9.72e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg02951883 chr7:2050386 MAD1L1 -0.75 -12.84 -0.57 4.43e-31 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg08280861 chr8:58055591 NA 0.49 6.13 0.31 2.38e-9 Developmental language disorder (linguistic errors); LIHC cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7647973 1.000 rs940045 chr3:49449638 G/A cg07636037 chr3:49044803 WDR6 0.5 6.23 0.32 1.36e-9 Menarche (age at onset); LIHC cis rs561341 1.000 rs56362439 chr17:30253140 T/A cg12193833 chr17:30244370 NA -0.56 -6.01 -0.31 4.65e-9 Hip circumference adjusted for BMI; LIHC cis rs748404 0.560 rs570933 chr15:43824030 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.39 5.88 0.3 9.85e-9 Lung cancer; LIHC cis rs7584330 0.554 rs77648388 chr2:238431832 G/C cg08992911 chr2:238395768 MLPH 0.55 6.21 0.32 1.52e-9 Prostate cancer; LIHC trans rs75804782 0.572 rs72982580 chr2:239447783 A/G cg01134436 chr17:81009848 B3GNTL1 0.74 6.27 0.32 1.11e-9 Morning vs. evening chronotype;Chronotype; LIHC cis rs7412746 0.634 rs12562939 chr1:150951452 A/C cg18016565 chr1:150552671 MCL1 0.52 9.57 0.46 2.2e-19 Melanoma; LIHC cis rs2243480 1.000 rs709607 chr7:65449541 C/G cg12463550 chr7:65579703 CRCP -0.59 -5.96 -0.31 6.21e-9 Diabetic kidney disease; LIHC trans rs916888 0.773 rs199533 chr17:44828931 G/A cg22968622 chr17:43663579 NA 1.17 12.88 0.57 3.32e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC cis rs34779708 0.966 rs10827491 chr10:35427395 G/A cg03585969 chr10:35415529 CREM 0.85 12.94 0.57 1.93e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs798554 0.660 rs2527694 chr7:2858240 T/C cg19346786 chr7:2764209 NA -0.36 -5.78 -0.3 1.65e-8 Height; LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.82 0.39 6.83e-14 Height; LIHC cis rs1707322 0.963 rs4508055 chr1:46257731 A/T cg03146154 chr1:46216737 IPP 0.49 7.66 0.38 1.99e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs796364 0.756 rs2949006 chr2:200715388 T/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.73 8.31 0.41 2.25e-15 Schizophrenia; LIHC cis rs4925386 0.765 rs6142737 chr20:60919800 C/G cg24112000 chr20:60950667 NA -0.45 -6.07 -0.31 3.34e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg12344004 chr15:89877906 POLG -0.49 -6.1 -0.31 2.92e-9 Systolic blood pressure; LIHC cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg06212747 chr3:49208901 KLHDC8B 0.65 8.87 0.43 4.27e-17 Menarche (age at onset); LIHC cis rs4319547 0.688 rs10847242 chr12:123079020 T/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.82 -0.39 6.77e-14 Body mass index; LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg24209194 chr3:40518798 ZNF619 -0.64 -9.72 -0.47 6.96e-20 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06366937 chr1:74663927 TNNI3K;FPGT;LRRIQ3 -0.44 -6.06 -0.31 3.6e-9 Pancreatic cancer; LIHC trans rs60752752 0.852 rs3014807 chr1:153368020 A/C cg14901121 chr8:98817630 LAPTM4B 0.4 6.67 0.34 1.02e-10 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17928095 chr1:156252714 TMEM79;SMG5 0.46 6.68 0.34 9.55e-11 Lung function (FEV1/FVC); LIHC cis rs7674212 0.539 rs6854709 chr4:104129786 A/G cg16532752 chr4:104119610 CENPE -0.45 -7.13 -0.36 5.98e-12 Type 2 diabetes; LIHC cis rs1552244 0.816 rs56271597 chr3:10042790 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.17 -0.44 4.37e-18 Alzheimer's disease; LIHC cis rs2153535 0.563 rs1796687 chr6:8536118 C/G cg07606381 chr6:8435919 SLC35B3 0.74 10.92 0.51 4.94e-24 Motion sickness; LIHC trans rs11098499 0.754 rs714899 chr4:120243035 G/A cg25214090 chr10:38739885 LOC399744 0.52 8.45 0.42 8.71e-16 Corneal astigmatism; LIHC cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg10802521 chr3:52805072 NEK4 -0.43 -7.26 -0.37 2.62e-12 Bipolar disorder; LIHC cis rs1670533 0.585 rs6827206 chr4:1065071 A/T cg27284194 chr4:1044797 NA 0.59 8.81 0.43 6.56e-17 Recombination rate (females); LIHC cis rs986417 0.901 rs1950312 chr14:60989784 A/G cg27398547 chr14:60952738 C14orf39 -0.78 -8.67 -0.42 1.81e-16 Gut microbiota (bacterial taxa); LIHC cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.65e-9 Menopause (age at onset); LIHC cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg00409905 chr10:38381863 ZNF37A -0.57 -9.49 -0.46 4.06e-19 Extrinsic epigenetic age acceleration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05902531 chr12:58239324 CTDSP2 -0.47 -6.93 -0.35 2.14e-11 Systolic blood pressure; LIHC cis rs2153535 0.525 rs1335644 chr6:8488041 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs12079745 0.793 rs78566263 chr1:169316011 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.79 -7.08 -0.36 8.09e-12 QT interval; LIHC cis rs6545883 0.895 rs2177961 chr2:61560264 T/C cg15711740 chr2:61764176 XPO1 0.42 5.76 0.3 1.85e-8 Tuberculosis; LIHC cis rs7520050 0.898 rs785502 chr1:46581444 T/C cg03146154 chr1:46216737 IPP -0.37 -6.2 -0.32 1.62e-9 Red blood cell count;Reticulocyte count; LIHC trans rs17301259 0.729 rs2519922 chr7:88379849 T/C cg07470830 chr6:76000847 NA 0.36 6.05 0.31 3.75e-9 Heschl's gyrus morphology; LIHC cis rs10242455 0.702 rs7794068 chr7:99146873 A/T cg18809830 chr7:99032528 PTCD1 -0.82 -6.63 -0.34 1.34e-10 Blood metabolite levels; LIHC cis rs7659604 0.540 rs10004284 chr4:122699222 A/T cg19671926 chr4:122722719 EXOSC9 0.55 8.56 0.42 3.92e-16 Type 2 diabetes; LIHC cis rs9457247 1.000 rs10946199 chr6:167404492 G/A cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.54e-20 Crohn's disease; LIHC cis rs1008375 1.000 rs6854733 chr4:17640526 C/T cg15017067 chr4:17643749 FAM184B 0.34 5.85 0.3 1.14e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7089973 0.584 rs4752322 chr10:116613258 A/C cg23260525 chr10:116636907 FAM160B1 0.39 7.73 0.39 1.19e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1707322 0.963 rs11211229 chr1:46400517 A/C cg03146154 chr1:46216737 IPP 0.48 7.74 0.39 1.13e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs35160687 0.644 rs4832264 chr2:86486834 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.35 5.75 0.3 2.01e-8 Night sleep phenotypes; LIHC cis rs7208859 0.725 rs6505215 chr17:29189903 C/A cg14067834 chr17:29058358 SUZ12P 0.62 6.38 0.33 5.64e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17401966 0.838 rs1013953 chr1:10319459 T/A cg19773385 chr1:10388646 KIF1B -0.4 -7.35 -0.37 1.46e-12 Hepatocellular carcinoma; LIHC cis rs11671005 0.735 rs3764529 chr19:58945089 A/G cg25952890 chr19:58913133 NA 0.7 7.64 0.38 2.23e-13 Mean platelet volume; LIHC cis rs6088580 0.602 rs6059834 chr20:33019299 A/G cg08999081 chr20:33150536 PIGU 0.67 13.26 0.58 1.15e-32 Glomerular filtration rate (creatinine); LIHC cis rs7264396 0.563 rs2425086 chr20:34302873 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC cis rs6546886 0.536 rs828870 chr2:74322244 A/G cg19729930 chr2:74357872 NA -0.32 -5.94 -0.31 7.13e-9 Dialysis-related mortality; LIHC cis rs9910055 0.530 rs2269905 chr17:42294462 A/G cg19774624 chr17:42201019 HDAC5 -0.56 -7.84 -0.39 5.63e-14 Total body bone mineral density; LIHC trans rs7674212 0.570 rs1031804 chr4:104066049 C/T cg16471864 chr4:38666270 KLF3;FLJ13197 -0.45 -6.44 -0.33 3.95e-10 Type 2 diabetes; LIHC cis rs3096299 0.874 rs3102342 chr16:89451575 T/C cg08392591 chr16:89556376 ANKRD11 0.41 6.11 0.31 2.7e-9 Multiple myeloma (IgH translocation); LIHC cis rs7546668 1.000 rs3795759 chr1:15853628 C/T cg11706911 chr1:15910989 AGMAT 0.44 6.82 0.35 4.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs11711311 1.000 rs9288982 chr3:113470149 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -6.88 -0.35 2.88e-11 IgG glycosylation; LIHC cis rs17001868 0.568 rs9607701 chr22:40739116 A/G cg07138101 chr22:40742427 ADSL 0.54 6.4 0.33 5.03e-10 Mammographic density (dense area); LIHC trans rs76485637 0.651 rs12921905 chr16:7989960 A/G cg15006175 chr8:145698660 KIFC2 -0.33 -6.04 -0.31 4.05e-9 Pediatric bone mineral density (spine); LIHC cis rs7772486 0.686 rs9497396 chr6:146014963 C/A cg23711669 chr6:146136114 FBXO30 -0.63 -11.47 -0.53 5.66e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs3780486 0.846 rs10971419 chr9:33124161 T/C cg20290983 chr6:43655470 MRPS18A 1.16 30.42 0.85 2.6e-99 IgG glycosylation; LIHC cis rs7772486 0.846 rs6908063 chr6:146403618 T/C cg23711669 chr6:146136114 FBXO30 0.58 10.08 0.48 4.26e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs782590 0.805 rs782578 chr2:55915904 A/C cg18811423 chr2:55921094 PNPT1 1.07 17.72 0.69 2.53e-50 Metabolic syndrome; LIHC cis rs1552244 0.882 rs9812006 chr3:10022658 T/C cg00149659 chr3:10157352 C3orf10 0.51 5.99 0.31 5.36e-9 Alzheimer's disease; LIHC cis rs4237845 0.537 rs11172369 chr12:58280592 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.59 7.97 0.4 2.35e-14 Intelligence (multi-trait analysis); LIHC cis rs6951245 0.515 rs73257955 chr7:1007014 G/A cg24642844 chr7:1081250 C7orf50 -0.83 -6.68 -0.34 9.72e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6960043 0.818 rs10807778 chr7:15054190 C/G cg19272540 chr7:15055459 NA 0.26 6.96 0.35 1.71e-11 Type 2 diabetes; LIHC cis rs240764 0.781 rs239227 chr6:101107089 C/G cg09795085 chr6:101329169 ASCC3 0.53 7.46 0.37 7.07e-13 Neuroticism; LIHC cis rs3770081 1.000 rs111295372 chr2:86283357 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.58 9.34 0.45 1.32e-18 Facial emotion recognition (sad faces); LIHC cis rs7412746 0.611 rs36008098 chr1:150856806 G/A cg18016565 chr1:150552671 MCL1 0.5 9.52 0.46 3.37e-19 Melanoma; LIHC cis rs739401 0.572 rs739400 chr11:3016520 G/A cg20651018 chr11:3035856 CARS -0.34 -5.9 -0.3 8.67e-9 Longevity; LIHC trans rs11165623 0.602 rs7521690 chr1:97015761 A/C cg10631902 chr5:14652156 NA -0.25 -6.18 -0.32 1.83e-9 Hip circumference;Waist circumference; LIHC cis rs9372253 0.678 rs9487392 chr6:110708626 C/T cg19196401 chr6:110721138 DDO 0.32 6.37 0.33 6.04e-10 Platelet distribution width; LIHC trans rs3780486 0.757 rs10758189 chr9:33125804 A/G cg04842962 chr6:43655489 MRPS18A 1.0 24.04 0.79 1.73e-75 IgG glycosylation; LIHC cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg06634786 chr22:41940651 POLR3H -0.81 -8.21 -0.41 4.61e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs55702914 0.746 rs4850425 chr2:198152786 T/C cg10820045 chr2:198174542 NA -0.41 -6.21 -0.32 1.54e-9 Major depression and alcohol dependence; LIHC cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.1 11.26 0.52 3.05e-25 Platelet count; LIHC cis rs6963495 0.818 rs6973974 chr7:105170629 C/T cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs7647973 0.626 rs62262672 chr3:49655927 T/A cg03060546 chr3:49711283 APEH -0.53 -5.77 -0.3 1.81e-8 Menarche (age at onset); LIHC cis rs8038465 0.561 rs59104311 chr15:73845185 G/A cg15420318 chr15:73925796 NPTN 0.5 7.2 0.36 3.87e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2303745 0.544 rs6512181 chr19:17399213 T/G cg10664184 chr19:17420304 DDA1 0.46 5.86 0.3 1.07e-8 Systemic lupus erythematosus; LIHC trans rs2727020 0.718 rs1404366 chr11:49415899 T/A cg15704280 chr7:45808275 SEPT13 -0.79 -12.55 -0.56 5.8e-30 Coronary artery disease; LIHC cis rs2304069 0.507 rs4705407 chr5:149404983 G/T cg02319142 chr5:149339858 SLC26A2 0.38 6.16 0.32 2.08e-9 HIV-1 control; LIHC cis rs943466 1.000 rs6933174 chr6:33751003 G/A cg25922239 chr6:33757077 LEMD2 -0.47 -5.77 -0.3 1.75e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs1997103 0.705 rs56301138 chr7:55396555 G/T cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs8078723 1.000 rs2227336 chr17:38174855 T/G cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.12 -0.44 6.77e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs11676348 0.846 rs4674257 chr2:218988774 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.15 -0.32 2.21e-9 Ulcerative colitis; LIHC cis rs12928939 0.815 rs34731378 chr16:71745748 C/T cg03805757 chr16:71968109 PKD1L3 -0.67 -7.71 -0.38 1.41e-13 Post bronchodilator FEV1; LIHC cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1165668 0.816 rs1866072 chr12:104310706 C/G cg21863207 chr12:104234989 NT5DC3 0.45 7.81 0.39 6.9e-14 Coronary heart disease (SNP X SNP interaction); LIHC cis rs9457247 0.765 rs4710171 chr6:167430186 A/G cg12798992 chr6:167411361 FGFR1OP 0.48 7.35 0.37 1.51e-12 Crohn's disease; LIHC cis rs11626933 1.000 rs61989986 chr14:90739180 G/A cg07150772 chr14:90864620 CALM1 -0.42 -5.88 -0.3 9.75e-9 Gut microbiota (bacterial taxa); LIHC trans rs2243480 1.000 rs35283677 chr7:65359233 C/T cg10756647 chr7:56101905 PSPH 1.11 13.23 0.58 1.43e-32 Diabetic kidney disease; LIHC cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 9.3 0.45 1.69e-18 Platelet count; LIHC cis rs11690935 0.959 rs7597387 chr2:172577116 T/C cg13550731 chr2:172543902 DYNC1I2 -0.94 -19.05 -0.72 1.13e-55 Schizophrenia; LIHC cis rs262150 0.630 rs2730274 chr7:158796062 C/A cg19418458 chr7:158789849 NA -0.33 -5.99 -0.31 5.37e-9 Facial morphology (factor 20); LIHC cis rs9640161 0.702 rs11765692 chr7:150026567 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.52 -9.14 -0.44 5.49e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs8180040 1.000 rs295461 chr3:47368010 T/C cg27129171 chr3:47204927 SETD2 0.63 10.84 0.51 9.98e-24 Colorectal cancer; LIHC cis rs1707322 0.964 rs6697830 chr1:46290477 C/A cg03146154 chr1:46216737 IPP 0.48 7.8 0.39 7.74e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs5758511 0.680 rs5751243 chr22:42617177 T/C cg00645731 chr22:42541494 CYP2D7P1 0.54 8.66 0.42 1.92e-16 Birth weight; LIHC cis rs7647973 1.000 rs12583 chr3:49571462 G/T cg07636037 chr3:49044803 WDR6 -0.54 -6.63 -0.34 1.33e-10 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26217633 chr17:33469413 NLE1 0.41 6.07 0.31 3.36e-9 Pancreatic cancer; LIHC cis rs9322817 0.691 rs2499666 chr6:105318576 A/G cg02098413 chr6:105308735 HACE1 0.42 7.71 0.38 1.35e-13 Thyroid stimulating hormone; LIHC trans rs4332037 0.539 rs55790766 chr7:2021248 C/T cg11693508 chr17:37793320 STARD3 0.68 6.93 0.35 2.09e-11 Bipolar disorder; LIHC cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg04317338 chr11:64019027 PLCB3 0.85 10.6 0.5 6.8e-23 Mean platelet volume; LIHC cis rs7927771 0.524 rs7933896 chr11:47882782 C/T cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.34e-24 Subjective well-being; LIHC cis rs2075371 1.000 rs2075371 chr7:133984127 A/G cg20476274 chr7:133979776 SLC35B4 0.75 12.53 0.56 6.44e-30 Mean platelet volume; LIHC cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs6582630 0.502 rs11182760 chr12:38606273 A/T cg13010199 chr12:38710504 ALG10B 0.57 6.76 0.34 6.15e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs76051363 0.500 rs73070422 chr4:1016645 C/G cg06222114 chr4:1004783 FGFRL1 -0.55 -5.87 -0.3 1.05e-8 Total body bone mineral density; LIHC cis rs5769765 1.000 rs8138941 chr22:50290678 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.15 -0.44 5.07e-18 Schizophrenia; LIHC cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg00656387 chr3:40428638 ENTPD3 0.41 6.76 0.34 5.8200000000000003e-11 Renal cell carcinoma; LIHC cis rs3853824 0.932 rs3986358 chr17:54898301 T/C cg13675837 chr17:54910204 DGKE 0.4 6.0 0.31 5.16e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3806843 0.966 rs2563261 chr5:140137713 G/T cg19875535 chr5:140030758 IK -0.37 -6.04 -0.31 4.11e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg07424592 chr7:64974309 NA 0.79 8.97 0.44 1.98e-17 Diabetic kidney disease; LIHC trans rs11098499 0.955 rs1551 chr4:120158500 T/G cg25214090 chr10:38739885 LOC399744 0.53 8.02 0.4 1.68e-14 Corneal astigmatism; LIHC cis rs9868809 0.881 rs34368826 chr3:48670827 G/T cg07636037 chr3:49044803 WDR6 -0.55 -6.39 -0.33 5.38e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs600806 0.888 rs6695482 chr1:109870859 C/G cg23091122 chr1:110024289 SYPL2 -0.46 -6.06 -0.31 3.63e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs3768617 0.510 rs35968946 chr1:183114871 G/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.65 0.5 4.45e-23 Fuchs's corneal dystrophy; LIHC cis rs9297145 0.916 rs6969140 chr7:98753900 G/A cg05967295 chr7:98741636 SMURF1 -0.68 -10.43 -0.49 2.69e-22 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg16822855 chr3:40428330 ENTPD3 0.33 5.96 0.31 6.43e-9 Renal cell carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07781848 chr12:123868310 SETD8 0.48 6.47 0.33 3.46e-10 Lung function (FEV1/FVC); LIHC cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg16434002 chr17:42200994 HDAC5 -0.48 -7.17 -0.36 4.64e-12 Total body bone mineral density; LIHC cis rs2239815 0.576 rs10427628 chr22:29239766 T/C cg15103426 chr22:29168792 CCDC117 0.44 6.07 0.31 3.39e-9 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC cis rs67311347 1.000 rs9841335 chr3:40475858 G/A cg13409248 chr3:40428643 ENTPD3 0.41 6.9 0.35 2.58e-11 Renal cell carcinoma; LIHC cis rs2635047 0.615 rs2684819 chr18:44710691 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.93 0.31 7.28e-9 Educational attainment; LIHC cis rs4555082 0.957 rs2975216 chr14:105713134 T/C cg10792982 chr14:105748885 BRF1 0.42 5.95 0.31 6.65e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs7945705 0.967 rs10840147 chr11:8920704 A/G cg12365402 chr11:9010492 NRIP3 0.31 7.89 0.39 4.04e-14 Hemoglobin concentration; LIHC cis rs6463523 0.864 rs73047957 chr7:759373 A/T cg11064039 chr7:766100 PRKAR1B;HEATR2 1.03 18.24 0.7 2.12e-52 Subjective well-being; LIHC cis rs929354 0.713 rs3802129 chr7:156965297 G/A cg16102536 chr7:156981717 UBE3C 0.34 5.77 0.3 1.75e-8 Body mass index; LIHC cis rs11785693 0.862 rs73183618 chr8:4988340 T/C cg26367366 chr8:4980734 NA 0.6 6.63 0.34 1.33e-10 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs2838845 chr21:46670812 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 10.67 0.5 3.94e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3099143 1.000 rs2046415 chr15:77085253 A/G cg21673338 chr15:77095150 SCAPER -0.5 -7.56 -0.38 3.67e-13 Recalcitrant atopic dermatitis; LIHC cis rs4665809 1.000 rs4665820 chr2:26309150 T/C cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.02e-15 Gut microbiome composition (summer); LIHC cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg01368799 chr11:117014884 PAFAH1B2 -0.45 -6.39 -0.33 5.54e-10 Blood protein levels; LIHC cis rs9733 0.526 rs11204696 chr1:150658721 T/C cg17724175 chr1:150552817 MCL1 0.49 9.85 0.47 2.67e-20 Tonsillectomy; LIHC cis rs748404 0.697 rs473554 chr15:43568207 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.09 0.4 1.04e-14 Lung cancer; LIHC cis rs2797685 1.000 rs707472 chr1:7906008 A/C cg04725166 chr1:7887271 PER3 0.4 7.1 0.36 7.27e-12 Crohn's disease; LIHC cis rs3540 0.574 rs8035980 chr15:90974390 C/G cg22089800 chr15:90895588 ZNF774 0.58 8.02 0.4 1.72e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs1707322 1.000 rs1707337 chr1:46508769 A/G cg06784218 chr1:46089804 CCDC17 -0.37 -6.81 -0.35 4.39e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.679 rs72649114 chr8:58037491 G/T cg20607798 chr8:58055168 NA 0.46 6.62 0.34 1.42e-10 Developmental language disorder (linguistic errors); LIHC cis rs7659604 1.000 rs35901586 chr4:122664757 T/A cg19748678 chr4:122722346 EXOSC9 0.35 5.86 0.3 1.06e-8 Type 2 diabetes; LIHC cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg07061783 chr6:25882402 NA 0.43 5.93 0.31 7.31e-9 Blood metabolite levels; LIHC cis rs4891159 0.790 rs56077581 chr18:74116865 T/G cg24786174 chr18:74118243 ZNF516 -0.79 -14.39 -0.61 4.98e-37 Longevity; LIHC cis rs9467773 0.596 rs3001369 chr6:26670969 C/T cg11502198 chr6:26597334 ABT1 0.61 9.48 0.46 4.56e-19 Intelligence (multi-trait analysis); LIHC cis rs208520 1.000 rs12190187 chr6:66973207 T/G cg07460842 chr6:66804631 NA 0.69 7.27 0.37 2.52e-12 Exhaled nitric oxide output; LIHC trans rs17685 0.712 rs28456330 chr7:75810542 A/G cg19862616 chr7:65841803 NCRNA00174 0.89 18.15 0.7 4.86e-52 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg08280861 chr8:58055591 NA 0.49 6.11 0.31 2.69e-9 Developmental language disorder (linguistic errors); LIHC cis rs3749237 0.595 rs7643845 chr3:49530711 A/G cg07636037 chr3:49044803 WDR6 0.56 8.46 0.42 7.75e-16 Resting heart rate; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27309920 chr12:6798957 ZNF384 0.48 7.02 0.35 1.2e-11 Pancreatic cancer; LIHC trans rs9929218 1.000 rs11865026 chr16:68774283 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -9.27 -0.45 2.16e-18 Colorectal cancer; LIHC cis rs28530618 0.580 rs4607010 chr20:31255271 G/C cg13636640 chr20:31349939 DNMT3B -0.42 -5.87 -0.3 1.04e-8 Birth weight; LIHC cis rs477692 0.789 rs568166 chr10:131400088 G/A cg05714579 chr10:131428358 MGMT 0.47 7.76 0.39 9.73e-14 Response to temozolomide; LIHC cis rs12586317 0.547 rs116499019 chr14:35441931 T/C cg05294307 chr14:35346193 BAZ1A -0.47 -6.93 -0.35 2.15e-11 Psoriasis; LIHC cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg06238570 chr21:40685208 BRWD1 0.57 6.8 0.34 4.78e-11 Cognitive function; LIHC cis rs11673344 0.800 rs8108214 chr19:37516086 C/T cg27390819 chr19:37464633 NA 0.49 6.09 0.31 3.1e-9 Obesity-related traits; LIHC cis rs4728302 0.869 rs6954712 chr7:133618853 G/A cg10665199 chr7:133106180 EXOC4 0.36 6.15 0.32 2.22e-9 Intelligence;Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01587390 chr19:10221818 PPAN-P2RY11;P2RY11;PPAN 0.44 6.78 0.34 5.25e-11 Longevity; LIHC cis rs1003719 0.715 rs6579 chr21:38568308 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.24 -0.48 1.21e-21 Eye color traits; LIHC cis rs10751667 0.961 rs6597954 chr11:987677 G/A cg10932868 chr11:921992 NA 0.34 6.32 0.32 8.22e-10 Alzheimer's disease (late onset); LIHC cis rs2749592 0.918 rs4934590 chr10:37877569 T/C cg00409905 chr10:38381863 ZNF37A 0.43 6.42 0.33 4.47e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6586163 1.000 rs3824729 chr10:90752616 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.56 -8.3 -0.41 2.41e-15 Chronic lymphocytic leukemia; LIHC cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg15691649 chr6:25882328 NA 0.78 10.99 0.51 2.95e-24 Blood metabolite levels; LIHC cis rs7534824 0.625 rs3087816 chr1:101441775 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.69 7.02 0.35 1.22e-11 Refractive astigmatism; LIHC cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs2016586 0.929 rs5755924 chr22:36114621 A/G cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 7.96e-10 Body mass index; LIHC cis rs7264396 0.790 rs3787168 chr20:34233278 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.28 -0.52 2.73e-25 Total cholesterol levels; LIHC cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg11062466 chr8:58055876 NA 0.51 7.09 0.36 7.72e-12 Developmental language disorder (linguistic errors); LIHC cis rs7584330 0.554 rs10190935 chr2:238435482 G/A cg08992911 chr2:238395768 MLPH 0.5 6.06 0.31 3.63e-9 Prostate cancer; LIHC cis rs644799 1.000 rs3177463 chr11:95502128 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.13 0.68 6.02e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs763121 0.819 rs5757126 chr22:38923675 T/C cg06544989 chr22:39130855 UNC84B 0.39 5.87 0.3 1.06e-8 Menopause (age at onset); LIHC cis rs13064411 0.696 rs6438159 chr3:113217341 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg11235426 chr6:292522 DUSP22 -0.52 -6.88 -0.35 2.84e-11 Menopause (age at onset); LIHC cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg25894440 chr7:65020034 NA 0.55 6.21 0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs4891159 0.790 rs72973773 chr18:74115176 T/C cg24786174 chr18:74118243 ZNF516 -0.78 -14.31 -0.61 1e-36 Longevity; LIHC cis rs8067354 0.645 rs2271304 chr17:57814641 A/G cg02344993 chr17:57696989 CLTC 0.71 11.8 0.54 3.5e-27 Hemoglobin concentration; LIHC cis rs6503525 0.591 rs8080734 chr17:38103285 G/A cg17467752 chr17:38218738 THRA 0.42 6.94 0.35 2.01e-11 Asthma; LIHC cis rs1419980 0.730 rs7958896 chr12:7774118 A/G cg10578777 chr12:7781093 NA -0.39 -5.79 -0.3 1.55e-8 HDL cholesterol levels; LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 25.06 0.8 2.11e-79 Prudent dietary pattern; LIHC cis rs6061231 0.631 rs2427310 chr20:60969929 C/G cg24112000 chr20:60950667 NA -0.61 -9.79 -0.47 3.98e-20 Colorectal cancer; LIHC cis rs3020736 0.500 rs5996109 chr22:42493098 A/G cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg10862848 chr6:42927986 GNMT -0.3 -6.79 -0.34 4.98e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs11792861 0.926 rs11788904 chr9:111865052 T/C cg05043794 chr9:111880884 C9orf5 -0.31 -7.24 -0.36 3.07e-12 Menarche (age at onset); LIHC cis rs4853036 0.904 rs7578366 chr2:70135695 C/T cg02498382 chr2:70120550 SNRNP27 -0.42 -6.75 -0.34 6.19e-11 Colorectal or endometrial cancer; LIHC cis rs1348850 0.597 rs13014512 chr2:178470851 T/A cg27490568 chr2:178487706 NA 0.82 9.74 0.47 6.06e-20 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1153858 1.000 rs9783731 chr15:45642884 C/T cg14582100 chr15:45693742 SPATA5L1 -0.31 -6.16 -0.32 2.02e-9 Homoarginine levels; LIHC cis rs7534824 0.625 rs61782085 chr1:101518270 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.72 7.2 0.36 3.92e-12 Refractive astigmatism; LIHC cis rs9952991 0.941 rs7237497 chr18:12777325 T/C cg23598886 chr18:12777645 NA 0.48 6.48 0.33 3.13e-10 Inflammatory skin disease; LIHC cis rs72781680 0.898 rs72782138 chr2:24048162 T/C cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg20090690 chr10:134436459 INPP5A 0.44 5.8 0.3 1.5e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12701220 0.655 rs34696066 chr7:1140919 C/T cg16145915 chr7:1198662 ZFAND2A -0.35 -7.02 -0.36 1.16e-11 Bronchopulmonary dysplasia; LIHC cis rs1577917 0.629 rs6927475 chr6:86206773 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.42 7.7 0.38 1.47e-13 Response to antipsychotic treatment; LIHC cis rs2070488 1.000 rs2070488 chr3:38442490 A/G cg24069376 chr3:38537580 EXOG -0.4 -7.49 -0.38 5.97e-13 Electrocardiographic conduction measures; LIHC cis rs17106184 1.000 rs72902744 chr1:51243642 A/G cg07174182 chr1:51127561 FAF1 -0.61 -6.65 -0.34 1.18e-10 Type 2 diabetes; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg26338869 chr17:61819248 STRADA 0.61 8.76 0.43 8.92e-17 Prudent dietary pattern; LIHC cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg16325326 chr1:53192061 ZYG11B -0.41 -6.92 -0.35 2.23e-11 Monocyte count; LIHC cis rs116095464 0.558 rs28729548 chr5:229025 C/T cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs1997103 1.000 rs10224446 chr7:55413147 C/G cg17469321 chr7:55412551 NA 0.49 7.19 0.36 3.98e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6547741 0.967 rs4665986 chr2:27755168 G/A cg27432699 chr2:27873401 GPN1 0.71 11.39 0.52 1.11e-25 Oral cavity cancer; LIHC cis rs7267979 0.527 rs6083891 chr20:25574272 C/G cg24626310 chr20:25276739 ABHD12;PYGB -0.44 -6.02 -0.31 4.47e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2070433 0.534 rs2839269 chr21:47891491 A/G cg12379764 chr21:47803548 PCNT 0.55 8.06 0.4 1.33e-14 Lymphocyte counts; LIHC cis rs7726839 0.507 rs72703100 chr5:614291 C/T cg09021430 chr5:549028 NA -0.42 -8.48 -0.42 7.01e-16 Obesity-related traits; LIHC cis rs10791097 0.739 rs11222358 chr11:130730497 G/A cg12179176 chr11:130786555 SNX19 0.74 11.52 0.53 3.52e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6430585 0.591 rs724326 chr2:136485971 T/C cg07169764 chr2:136633963 MCM6 0.67 8.57 0.42 3.69e-16 Corneal structure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06818786 chr11:71639753 RNF121;LOC100133315 0.42 6.08 0.31 3.22e-9 Cognitive function; LIHC cis rs6831352 0.918 rs13138294 chr4:100062675 T/G cg12011299 chr4:100065546 ADH4 -0.62 -10.39 -0.49 3.62e-22 Alcohol dependence; LIHC cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg22907277 chr7:1156413 C7orf50 0.43 6.12 0.31 2.51e-9 Longevity;Endometriosis; LIHC cis rs4716602 0.596 rs10275400 chr7:156161550 A/G cg16983916 chr7:156159713 NA -0.33 -5.87 -0.3 1.01e-8 Anti-saccade response; LIHC cis rs1215050 0.740 rs10025482 chr4:99053277 T/C cg05340658 chr4:99064831 C4orf37 0.4 6.3 0.32 9.28e-10 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4072980 0.527 rs11210825 chr1:38446986 G/A cg12658694 chr1:38397304 INPP5B 0.51 7.84 0.39 5.83e-14 Coronary artery disease; LIHC trans rs1200821 0.535 rs1208789 chr10:37722472 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -6.59 -0.34 1.64e-10 Hemostatic factors and hematological phenotypes; LIHC cis rs6933660 0.745 rs6557138 chr6:151732017 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.66 11.06 0.51 1.66e-24 Menarche (age at onset); LIHC cis rs7552404 0.731 rs17650138 chr1:76398887 C/T cg10523679 chr1:76189770 ACADM -0.59 -6.67 -0.34 1.06e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg13271783 chr10:134563150 INPP5A -0.59 -6.96 -0.35 1.8e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7772486 0.754 rs9373475 chr6:146126419 C/T cg23711669 chr6:146136114 FBXO30 0.75 13.6 0.59 5.64e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs2842992 0.662 rs2273826 chr6:160211421 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs12995491 0.569 rs6724281 chr2:88529531 T/G cg07952391 chr2:88470173 THNSL2 -0.71 -9.11 -0.44 7.04e-18 Response to metformin (IC50); LIHC cis rs916888 0.687 rs199456 chr17:44797919 C/T cg15921436 chr17:44337874 NA 0.65 6.6 0.34 1.54e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11792861 0.781 rs28361152 chr9:111727529 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 9.09 0.44 8.39e-18 Menarche (age at onset); LIHC cis rs6964587 0.708 rs38800 chr7:92046191 C/G cg17063962 chr7:91808500 NA -0.85 -13.66 -0.59 3.28e-34 Breast cancer; LIHC cis rs17253792 0.558 rs10083353 chr14:56066370 G/T cg01858014 chr14:56050164 KTN1 -0.78 -8.48 -0.42 6.87e-16 Putamen volume; LIHC cis rs10870270 1.000 rs72636963 chr10:133771271 C/T cg08754478 chr10:133766260 PPP2R2D -0.55 -8.05 -0.4 1.37e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs651907 0.535 rs11707250 chr3:101509371 A/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.64 -10.14 -0.48 2.68e-21 Colorectal cancer; LIHC cis rs7107174 1.000 rs2511171 chr11:77930935 G/A cg02023728 chr11:77925099 USP35 0.5 9.35 0.45 1.19e-18 Testicular germ cell tumor; LIHC cis rs739401 0.611 rs391188 chr11:3047634 G/A cg08508325 chr11:3079039 CARS -0.33 -7.09 -0.36 7.53e-12 Longevity; LIHC cis rs7044106 0.791 rs10984997 chr9:123481206 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.2 0.52 5.25e-25 Hip circumference adjusted for BMI; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25396690 chr2:7006004 CMPK2 -0.61 -6.93 -0.35 2.05e-11 Systolic blood pressure; LIHC trans rs2739330 0.828 rs5760098 chr22:24248314 A/G cg06437703 chr8:37914619 EIF4EBP1 -0.49 -7.2 -0.36 3.78e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2292096 0.850 rs12747569 chr1:200745215 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.03 -0.31 4.17e-9 Epilepsy; LIHC cis rs6815814 0.731 rs4513579 chr4:38773816 T/C cg06935464 chr4:38784597 TLR10 0.38 5.96 0.31 6.18e-9 Breast cancer; LIHC cis rs4908768 0.534 rs11586056 chr1:8845199 G/T cg20416874 chr1:8611966 RERE 0.45 6.44 0.33 4.04e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs12477438 0.501 rs13000731 chr2:99795231 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs6747952 0.899 rs1374387 chr2:239085687 A/C cg17459225 chr2:239074497 NA 0.36 5.81 0.3 1.4e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2304069 0.545 rs1864998 chr5:149389465 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.6 8.49 0.42 6.46e-16 HIV-1 control; LIHC cis rs769267 0.930 rs6909 chr19:19619542 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.0 0.31 5.11e-9 Tonsillectomy; LIHC cis rs5758511 0.680 rs1033459 chr22:42619067 A/G cg00645731 chr22:42541494 CYP2D7P1 0.54 8.63 0.42 2.42e-16 Birth weight; LIHC cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg12310025 chr6:25882481 NA 0.88 12.24 0.55 7.93e-29 Blood metabolite levels; LIHC cis rs16828019 0.929 rs35286837 chr1:41682998 T/G cg03962019 chr1:41807865 NA 0.5 7.32 0.37 1.84e-12 Intelligence (multi-trait analysis); LIHC cis rs7927771 1.000 rs12419692 chr11:47624714 A/C cg20135002 chr11:47629003 NA 0.58 10.16 0.48 2.36e-21 Subjective well-being; LIHC cis rs8081395 0.801 rs2645479 chr17:57920532 A/G cg13753209 chr17:57696993 CLTC 0.46 7.1 0.36 7.07e-12 White blood cell count; LIHC cis rs9733 0.569 rs11204691 chr1:150644339 A/T cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs6964587 0.869 rs405 chr7:91546327 G/C cg17063962 chr7:91808500 NA -0.97 -18.25 -0.7 1.88e-52 Breast cancer; LIHC cis rs10752881 0.905 rs12132262 chr1:182989949 T/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.41 0.49 3.07e-22 Colorectal cancer; LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg06656553 chr16:89960601 TCF25 -0.49 -6.26 -0.32 1.13e-9 Skin colour saturation; LIHC cis rs172166 0.694 rs1770131 chr6:28086413 C/T cg23485639 chr6:28045615 ZNF165 0.4 6.3 0.32 9.03e-10 Cardiac Troponin-T levels; LIHC cis rs4555082 0.957 rs8022526 chr14:105756485 A/G cg13114125 chr14:105738426 BRF1 -0.66 -9.03 -0.44 1.26e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs10870270 0.956 rs10781555 chr10:133745720 G/A cg26149184 chr10:133730230 NA 0.47 7.36 0.37 1.36e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs868036 0.681 rs4776976 chr15:68103291 C/T cg24579218 chr15:68104479 NA -0.34 -5.79 -0.3 1.58e-8 Restless legs syndrome; LIHC cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.33 -0.37 1.71e-12 Bipolar disorder; LIHC trans rs916888 0.773 rs199448 chr17:44809001 A/G cg07870213 chr5:140052090 DND1 1.05 10.88 0.51 7.21e-24 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11792861 0.926 rs72607170 chr9:111836941 G/A cg13535736 chr9:111863775 C9orf5 -0.38 -5.81 -0.3 1.44e-8 Menarche (age at onset); LIHC cis rs8062405 0.755 rs4787456 chr16:28559573 C/T cg00204512 chr16:28754710 NA 0.41 7.16 0.36 4.9e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3008870 1.000 rs4655663 chr1:67430103 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.97 16.94 0.68 3.57e-47 Lymphocyte percentage of white cells; LIHC trans rs916888 0.773 rs199533 chr17:44828931 G/A cg26692224 chr17:62915920 LRRC37A3 -0.73 -7.05 -0.36 9.77e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11098499 0.954 rs10014845 chr4:120301077 T/G cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs1419980 0.730 rs11054944 chr12:7783201 A/C cg10578777 chr12:7781093 NA -0.4 -5.74 -0.3 2.15e-8 HDL cholesterol levels; LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg10687131 chr2:20871002 GDF7 -0.38 -7.31 -0.37 1.88e-12 Abdominal aortic aneurysm; LIHC cis rs919433 0.756 rs7575389 chr2:198198489 A/G cg10820045 chr2:198174542 NA -0.55 -8.95 -0.44 2.34e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2576037 0.566 rs2437854 chr18:44557613 T/C cg19077165 chr18:44547161 KATNAL2 0.47 6.88 0.35 2.82e-11 Personality dimensions; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25053907 chr4:492859 ZNF721;PIGG 0.44 6.12 0.31 2.58e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4888262 0.564 rs8062404 chr16:74611675 T/C cg01733217 chr16:74700730 RFWD3 0.82 16.12 0.66 6.98e-44 Testicular germ cell tumor; LIHC cis rs9303280 0.806 rs4795395 chr17:37962987 T/A cg00129232 chr17:37814104 STARD3 -0.35 -5.74 -0.3 2.07e-8 Self-reported allergy; LIHC cis rs950169 0.922 rs4338765 chr15:84916836 G/T cg17507749 chr15:85114479 UBE2QP1 0.76 9.02 0.44 1.36e-17 Schizophrenia; LIHC cis rs11098499 0.604 rs2389882 chr4:120566733 A/C cg09307838 chr4:120376055 NA 0.63 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs8017423 0.967 rs7147952 chr14:90720831 G/A cg04374321 chr14:90722782 PSMC1 0.75 14.91 0.63 4.48e-39 Mortality in heart failure; LIHC cis rs7512552 0.839 rs834231 chr1:150389392 A/T cg15654264 chr1:150340011 RPRD2 -0.68 -11.57 -0.53 2.48e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs6964587 0.935 rs9770444 chr7:91783162 T/G cg17063962 chr7:91808500 NA 1.05 22.28 0.77 1.42e-68 Breast cancer; LIHC cis rs10849893 0.554 rs10849888 chr12:121892786 A/G cg01154721 chr12:121881891 KDM2B -0.39 -6.82 -0.35 4.08e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs8141529 0.748 rs5762882 chr22:29290680 C/A cg02153584 chr22:29168773 CCDC117 0.51 7.98 0.4 2.25e-14 Lymphocyte counts; LIHC cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg02290350 chr8:58132656 NA 0.4 8.21 0.41 4.42e-15 Developmental language disorder (linguistic errors); LIHC cis rs2976388 1.000 rs2920293 chr8:143765414 C/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.92 -0.3 7.72e-9 Urinary tract infection frequency; LIHC cis rs3768617 0.610 rs10911228 chr1:183049792 T/C ch.1.3577855R chr1:183094577 LAMC1 0.48 7.63 0.38 2.29e-13 Fuchs's corneal dystrophy; LIHC cis rs507080 0.961 rs4938522 chr11:118548671 A/T cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07949612 chr2:69664562 NFU1 0.48 6.92 0.35 2.19e-11 Lung function (FEV1/FVC); LIHC cis rs2576037 0.526 rs571181 chr18:44376399 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.54 8.16 0.4 6.33e-15 Personality dimensions; LIHC cis rs9790314 1.000 rs975323 chr3:161021322 A/G cg03342759 chr3:160939853 NMD3 -0.72 -8.78 -0.43 7.96e-17 Morning vs. evening chronotype; LIHC cis rs10504229 1.000 rs59275611 chr8:58195191 G/A cg20607798 chr8:58055168 NA 0.58 6.77 0.34 5.5e-11 Developmental language disorder (linguistic errors); LIHC cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg18404041 chr3:52824283 ITIH1 -0.58 -9.2 -0.45 3.56e-18 Bipolar disorder; LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs11628318 0.614 rs7143048 chr14:103119800 C/T cg12046867 chr14:103022105 NA 0.48 6.83 0.35 3.89e-11 Platelet count; LIHC trans rs11098499 0.874 rs10022508 chr4:120115228 A/G cg25214090 chr10:38739885 LOC399744 0.45 7.27 0.37 2.49e-12 Corneal astigmatism; LIHC cis rs72829446 0.530 rs56078345 chr17:7394341 T/C cg02795151 chr17:7402630 POLR2A 0.51 5.81 0.3 1.44e-8 Androgen levels; LIHC cis rs2228479 0.850 rs1800331 chr16:89858417 C/A cg06558623 chr16:89946397 TCF25 0.83 10.92 0.51 5.22e-24 Skin colour saturation; LIHC cis rs4803468 0.967 rs3826713 chr19:41892269 C/T cg09537434 chr19:41945824 ATP5SL -0.99 -20.25 -0.74 1.79e-60 Height; LIHC cis rs763121 0.853 rs3761454 chr22:39066820 C/T cg14440974 chr22:39074834 NA -0.44 -7.15 -0.36 5.43e-12 Menopause (age at onset); LIHC cis rs1580019 0.522 rs10951340 chr7:32562408 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 26.45 0.82 1.05e-84 Cognitive ability; LIHC cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg16049864 chr8:95962084 TP53INP1 -0.53 -9.55 -0.46 2.65e-19 Type 2 diabetes; LIHC cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.87 7.82 0.39 6.72e-14 Platelet count; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26308477 chr20:44065479 NA -0.48 -6.1 -0.31 2.84e-9 Systolic blood pressure; LIHC cis rs6933660 0.721 rs2128945 chr6:151767907 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 7.29 0.37 2.15e-12 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19315081 chr11:10326100 ADM 0.5 7.23 0.36 3.24e-12 Pancreatic cancer; LIHC cis rs12472274 0.941 rs12616232 chr2:239080093 C/T cg17459225 chr2:239074497 NA 0.76 12.47 0.56 1.17e-29 Phospholipid levels (plasma); LIHC cis rs2404602 0.692 rs34478400 chr15:76923510 C/T cg03037974 chr15:76606532 NA 0.74 14.46 0.62 2.52e-37 Blood metabolite levels; LIHC cis rs6912958 0.558 rs7741825 chr6:88327338 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.38 -6.63 -0.34 1.33e-10 Monocyte percentage of white cells; LIHC cis rs11764590 0.694 rs4721359 chr7:2104951 A/G cg23422044 chr7:1970798 MAD1L1 -0.54 -8.62 -0.42 2.54e-16 Neuroticism; LIHC cis rs9811920 0.609 rs4928232 chr3:99694217 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.91 0.35 2.32e-11 Axial length; LIHC cis rs1419980 0.630 rs2080126 chr12:7774524 A/C cg14906510 chr12:7781169 NA 0.48 7.4 0.37 1.07e-12 HDL cholesterol levels; LIHC cis rs10791097 0.703 rs11222360 chr11:130730871 C/T cg12179176 chr11:130786555 SNX19 0.72 11.44 0.53 7.22e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg00656387 chr3:40428638 ENTPD3 0.47 7.79 0.39 8.3e-14 Renal cell carcinoma; LIHC cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs992157 1.000 rs736731 chr2:219120588 A/G cg00012203 chr2:219082015 ARPC2 0.91 15.08 0.63 9.78e-40 Colorectal cancer; LIHC cis rs13161895 0.591 rs12655422 chr5:179480825 C/A cg06664874 chr5:179499304 RNF130 0.64 7.33 0.37 1.71e-12 LDL cholesterol; LIHC trans rs1432089 0.773 rs6844102 chr4:171784000 G/A cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg23758822 chr17:41437982 NA 0.94 17.91 0.7 4.57e-51 Menopause (age at onset); LIHC cis rs7582720 0.943 rs72936839 chr2:203773237 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6582630 0.519 rs12372510 chr12:38293074 T/C cg26384229 chr12:38710491 ALG10B 0.57 7.75 0.39 1.06e-13 Drug-induced liver injury (flucloxacillin); LIHC cis rs7103648 0.966 rs10769263 chr11:47417183 A/C cg20307385 chr11:47447363 PSMC3 1.0 17.19 0.68 3.43e-48 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs6427508 1 rs6427508 chr1:160238857 T/C cg02974968 chr1:160236444 NA -0.41 -8.68 -0.42 1.62e-16 Breast size; LIHC cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg11890956 chr21:40555474 PSMG1 1.03 14.58 0.62 8.66e-38 Cognitive function; LIHC cis rs6502050 0.842 rs6502053 chr17:80066714 C/T cg11859384 chr17:80120422 CCDC57 0.44 5.97 0.31 5.92e-9 Life satisfaction; LIHC cis rs9910055 0.550 rs113844752 chr17:42297631 C/A cg13607699 chr17:42295918 UBTF 0.77 15.73 0.65 2.48e-42 Total body bone mineral density; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19763699 chr10:17756784 STAM -0.31 -6.62 -0.34 1.4e-10 Calcium levels; LIHC trans rs10230207 0.893 rs4337996 chr7:19616566 A/T cg04830814 chr5:32174484 GOLPH3 -0.41 -6.11 -0.31 2.77e-9 Intracranial aneurysm; LIHC cis rs9367716 0.868 rs9396267 chr6:57110411 C/G cg03371099 chr6:57305889 PRIM2 0.35 5.71 0.3 2.4e-8 Coronary artery disease; LIHC cis rs9896052 0.580 rs6416846 chr17:73462573 A/G cg25649188 chr17:73499917 CASKIN2 0.5 7.43 0.37 8.87e-13 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs2637266 0.905 rs1978925 chr10:78399879 C/T cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs8044868 0.530 rs2288002 chr16:72057282 A/G cg16558253 chr16:72132732 DHX38 -0.36 -5.87 -0.3 1.05e-8 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs6754311 0.638 rs2322659 chr2:136555659 A/G cg07169764 chr2:136633963 MCM6 -0.69 -9.73 -0.47 6.56e-20 Mosquito bite size; LIHC cis rs7487075 0.780 rs2279559 chr12:46767175 A/C cg21428710 chr12:47219797 SLC38A4 0.28 5.92 0.31 7.71e-9 Itch intensity from mosquito bite; LIHC cis rs17539620 0.624 rs62432735 chr6:154834055 T/C cg20019720 chr6:154832845 CNKSR3 0.43 6.29 0.32 9.97e-10 Lipoprotein (a) levels; LIHC cis rs1371867 0.513 rs1542812 chr8:101207064 G/A cg06636551 chr8:101224915 SPAG1 0.55 10.38 0.49 4.13e-22 Atrioventricular conduction; LIHC cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg00091569 chr3:40428383 ENTPD3 0.37 6.31 0.32 8.47e-10 Renal cell carcinoma; LIHC trans rs1005277 0.577 rs4934906 chr10:38015028 C/T cg17830980 chr10:43048298 ZNF37B -0.42 -8.08 -0.4 1.1e-14 Extrinsic epigenetic age acceleration; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg01374398 chr3:47516975 SCAP 0.47 6.63 0.34 1.35e-10 Migraine with aura; LIHC cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg11890956 chr21:40555474 PSMG1 0.95 13.51 0.59 1.26e-33 Cognitive function; LIHC cis rs1843834 0.898 rs11887386 chr2:225526975 T/G cg22509189 chr2:225307070 NA -0.54 -7.06 -0.36 9.44e-12 IgE levels in asthmatics (D.p. specific); LIHC trans rs9929218 0.954 rs72785165 chr16:68755635 T/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.6 -9.16 -0.44 4.8e-18 Colorectal cancer; LIHC cis rs9814567 0.929 rs9815297 chr3:134215052 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.47e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12478296 1.000 rs4973685 chr2:243019089 A/C cg18898632 chr2:242989856 NA -0.7 -8.87 -0.43 4.22e-17 Obesity-related traits; LIHC cis rs7312933 1.000 rs12372597 chr12:42412850 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.88 0.35 2.78e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs526821 0.553 rs295597 chr11:55470003 T/C cg15704280 chr7:45808275 SEPT13 -0.52 -7.7 -0.38 1.52e-13 Pediatric bone mineral density (spine); LIHC cis rs5769765 1.000 rs768618 chr22:50286827 G/A cg26441486 chr22:50317300 CRELD2 0.35 6.33 0.32 7.65e-10 Schizophrenia; LIHC cis rs8180040 0.764 rs4082155 chr3:47125385 G/A cg27129171 chr3:47204927 SETD2 0.68 11.92 0.54 1.25e-27 Colorectal cancer; LIHC cis rs7091068 0.615 rs11187609 chr10:95467031 A/C cg20715218 chr10:95462985 C10orf4 0.6 6.93 0.35 2.16e-11 Urinary tract infection frequency; LIHC cis rs6964587 1.000 rs10228334 chr7:91713972 C/T cg17063962 chr7:91808500 NA 1.0 19.05 0.72 1.18e-55 Breast cancer; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg14611757 chr11:1012211 AP2A2 0.61 6.2 0.32 1.58e-9 Mean platelet volume; LIHC cis rs35110281 0.811 rs2838337 chr21:45072621 A/C cg01579765 chr21:45077557 HSF2BP -0.33 -6.24 -0.32 1.27e-9 Mean corpuscular volume; LIHC cis rs240764 0.725 rs239193 chr6:101131848 T/C cg09795085 chr6:101329169 ASCC3 0.44 6.05 0.31 3.88e-9 Neuroticism; LIHC cis rs2439831 1.000 rs537115 chr15:43729948 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.67 0.59 3.13e-34 Lung cancer in ever smokers; LIHC trans rs12960119 0.536 rs11083162 chr18:23720997 T/A cg05333146 chr16:67183725 B3GNT9 0.64 6.06 0.31 3.57e-9 Rhegmatogenous retinal detachment; LIHC cis rs3753275 0.690 rs4908762 chr1:8563663 C/T cg20416874 chr1:8611966 RERE -0.47 -5.9 -0.3 8.95e-9 Educational attainment; LIHC cis rs3806843 0.676 rs2245643 chr5:140029780 C/T cg16577123 chr5:140027231 NDUFA2;IK -0.43 -6.33 -0.32 7.71e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs4653767 1.000 rs10916030 chr1:226919908 C/T cg05262829 chr1:226921576 ITPKB 0.44 8.25 0.41 3.4e-15 Parkinson's disease; LIHC trans rs1814175 0.519 rs3913237 chr11:49551828 G/A cg18944383 chr4:111397179 ENPEP -0.35 -8.02 -0.4 1.71e-14 Height; LIHC cis rs7647973 1.000 rs974495 chr3:49400482 T/C cg07636037 chr3:49044803 WDR6 0.5 6.22 0.32 1.45e-9 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07248407 chr19:10829176 MIR638;DNM2 -0.44 -6.31 -0.32 8.75e-10 Pancreatic cancer; LIHC cis rs9640161 0.830 rs13307276 chr7:150061525 T/C cg17279839 chr7:150038598 RARRES2 0.38 7.58 0.38 3.38e-13 Blood protein levels;Circulating chemerin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00054692 chr7:23338750 C7orf30 0.47 6.61 0.34 1.47e-10 Pancreatic cancer; LIHC cis rs17784882 0.524 rs7433300 chr3:47120640 G/A cg27129171 chr3:47204927 SETD2 0.53 8.54 0.42 4.44e-16 QT interval; LIHC cis rs6089829 0.962 rs6122344 chr20:61661738 C/T cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg03806693 chr22:41940476 POLR3H -0.95 -11.26 -0.52 3.02e-25 Vitiligo; LIHC cis rs11168351 0.889 rs12817104 chr12:48382573 G/C cg21466736 chr12:48725269 NA -0.44 -6.1 -0.31 2.85e-9 Bipolar disorder and schizophrenia; LIHC cis rs61990749 0.597 rs13379065 chr14:78141295 C/A cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.71 0.38 1.35e-13 Fibroblast growth factor basic levels; LIHC cis rs2075371 1.000 rs2598286 chr7:133976029 G/A cg20476274 chr7:133979776 SLC35B4 0.76 13.09 0.58 5.08e-32 Mean platelet volume; LIHC cis rs1075232 0.655 rs72711420 chr15:32170148 T/A cg01030201 chr15:31746330 NA -0.76 -5.73 -0.3 2.2e-8 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs7264396 0.690 rs2425172 chr20:34443893 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -10.72 -0.5 2.64e-23 Total cholesterol levels; LIHC cis rs911119 1.000 rs13039536 chr20:23612305 A/G cg16589663 chr20:23618590 CST3 0.75 7.77 0.39 9.23e-14 Chronic kidney disease; LIHC cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg07424592 chr7:64974309 NA 0.82 9.64 0.46 1.27e-19 Diabetic kidney disease; LIHC cis rs743757 0.878 rs6786523 chr3:50524221 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.46 -7.02 -0.36 1.18e-11 Diastolic blood pressure; LIHC cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg03452623 chr4:187889614 NA -0.32 -8.08 -0.4 1.16e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg02244288 chr16:89573955 SPG7 -0.32 -6.17 -0.32 1.91e-9 Multiple myeloma (IgH translocation); LIHC cis rs7944584 0.655 rs11039183 chr11:47346940 G/A cg20307385 chr11:47447363 PSMC3 0.6 6.44 0.33 4.1e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs1065656 0.563 rs391546 chr16:1915581 T/G cg00564555 chr16:1970112 NA 0.27 6.23 0.32 1.39e-9 Insulin-like growth factors; LIHC cis rs9790314 0.934 rs461638 chr3:161103166 A/G cg03342759 chr3:160939853 NMD3 -0.67 -8.05 -0.4 1.4e-14 Morning vs. evening chronotype; LIHC cis rs3135071 1.000 rs3135071 chr4:2406321 C/T cg27239842 chr4:2403781 ZFYVE28 0.54 6.35 0.32 6.72e-10 Influenza A (H1N1) severity; LIHC cis rs8067354 0.574 rs2250526 chr17:57951973 G/A cg02344993 chr17:57696989 CLTC 0.64 10.01 0.48 7.25e-21 Hemoglobin concentration; LIHC cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.99 8.93 0.43 2.62e-17 Platelet count; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg02207200 chr8:17353980 SLC7A2 -0.47 -6.09 -0.31 2.97e-9 Monocyte count; LIHC cis rs8077889 1.000 rs4793035 chr17:41887753 C/T cg26893861 chr17:41843967 DUSP3 0.98 10.7 0.5 3.12e-23 Triglycerides; LIHC cis rs600626 0.529 rs57188913 chr11:75473294 T/C cg24262691 chr11:75473276 NA 0.44 6.56 0.33 2e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs67478160 0.679 rs7156834 chr14:104211180 G/A cg08213375 chr14:104286397 PPP1R13B 0.65 12.55 0.56 5.65e-30 Schizophrenia; LIHC cis rs11671005 0.779 rs3794970 chr19:58986260 C/T cg25952890 chr19:58913133 NA -0.59 -6.09 -0.31 3.04e-9 Mean platelet volume; LIHC cis rs9633740 0.842 rs1870140 chr10:82246749 A/G cg01528321 chr10:82214614 TSPAN14 0.94 10.45 0.49 2.34e-22 Post bronchodilator FEV1; LIHC cis rs4820294 0.516 rs12627973 chr22:38096697 A/G cg00292662 chr22:38071168 LGALS1 0.65 8.48 0.42 6.78e-16 Fat distribution (HIV); LIHC cis rs798554 0.797 rs798487 chr7:2802943 G/A cg19717773 chr7:2847554 GNA12 -0.41 -6.63 -0.34 1.28e-10 Height; LIHC cis rs5769765 0.542 rs1033666 chr22:50252783 T/C cg02269571 chr22:50332266 NA 0.7 8.05 0.4 1.38e-14 Schizophrenia; LIHC cis rs9303401 0.659 rs17822837 chr17:56737838 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.98 14.28 0.61 1.29e-36 Cognitive test performance; LIHC trans rs61332075 0.501 rs56387323 chr2:239387399 T/C cg01134436 chr17:81009848 B3GNTL1 0.86 7.2 0.36 3.82e-12 Lung function (FEV1/FVC); LIHC cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg18305652 chr10:134549665 INPP5A 0.47 7.65 0.38 2.07e-13 Migraine; LIHC cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.01 0.31 4.75e-9 Schizophrenia; LIHC cis rs1941023 0.584 rs950803 chr11:60152563 A/T cg08716584 chr11:60157161 MS4A7 0.37 8.52 0.42 5.35e-16 Congenital heart disease (maternal effect); LIHC cis rs1823913 1.000 rs4853564 chr2:192123665 C/T cg12404831 chr2:192114017 MYO1B -0.32 -6.54 -0.33 2.21e-10 Obesity-related traits; LIHC cis rs4919087 0.810 rs1572437 chr10:99029278 A/G cg25902810 chr10:99078978 FRAT1 0.65 9.53 0.46 2.93e-19 Monocyte count; LIHC cis rs17152411 1.000 rs17152381 chr10:126592903 T/G cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs644799 0.932 rs572015 chr11:95637416 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.65 8.83 0.43 5.46e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs727505 0.954 rs59670428 chr7:124520966 C/A cg23710748 chr7:124431027 NA -0.32 -5.91 -0.3 8.38e-9 Lewy body disease; LIHC cis rs35146811 0.586 rs6964754 chr7:99589404 G/A cg19636519 chr7:99541626 NA 0.3 5.74 0.3 2.07e-8 Coronary artery disease; LIHC cis rs1552244 0.572 rs3894321 chr3:10168892 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 8.04 0.4 1.47e-14 Alzheimer's disease; LIHC cis rs6754311 0.773 rs309176 chr2:136622216 T/C cg15123519 chr2:136567270 LCT 0.43 8.96 0.44 2.08e-17 Mosquito bite size; LIHC cis rs858239 0.539 rs6976957 chr7:23187333 T/A cg23682824 chr7:23144976 KLHL7 0.43 6.52 0.33 2.56e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.89 -0.51 6.7e-24 Platelet count; LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg13409248 chr3:40428643 ENTPD3 0.49 8.22 0.41 4.34e-15 Renal cell carcinoma; LIHC cis rs1371867 0.875 rs1788168 chr8:101324960 G/T cg06636551 chr8:101224915 SPAG1 -0.46 -8.7 -0.43 1.42e-16 Atrioventricular conduction; LIHC cis rs858239 0.601 rs4599714 chr7:23168801 C/T cg23682824 chr7:23144976 KLHL7 0.45 6.68 0.34 9.63e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2404602 0.647 rs11072619 chr15:77043242 A/C cg23625390 chr15:77176239 SCAPER -0.56 -9.54 -0.46 2.86e-19 Blood metabolite levels; LIHC cis rs875971 0.929 rs4122249 chr7:65920936 T/C cg18876405 chr7:65276391 NA 0.38 6.83 0.35 3.83e-11 Aortic root size; LIHC cis rs7903847 0.642 rs11189175 chr10:99139609 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.43 -0.33 4.2e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1577917 1.000 rs34622557 chr6:86630852 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs7586673 0.930 rs7591506 chr2:161960925 T/G cg16506815 chr2:162101123 NA 0.5 8.14 0.4 7.53e-15 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.791 rs6923074 chr6:145893332 T/C cg23711669 chr6:146136114 FBXO30 0.72 12.8 0.57 6.26e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs4919694 1.000 rs12241091 chr10:104808997 G/A cg04362960 chr10:104952993 NT5C2 1.14 8.87 0.43 4.02e-17 Arsenic metabolism; LIHC cis rs6429082 0.715 rs2291687 chr1:235594182 A/G cg26050004 chr1:235667680 B3GALNT2 -0.46 -7.04 -0.36 1.09e-11 Adiposity; LIHC cis rs7772486 0.720 rs4896844 chr6:146075224 T/C cg23711669 chr6:146136114 FBXO30 -0.74 -13.57 -0.59 7.41e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs10540 0.915 rs35389167 chr11:460765 A/G cg03352830 chr11:487213 PTDSS2 0.73 6.26 0.32 1.13e-9 Body mass index; LIHC cis rs2599510 0.811 rs2710625 chr2:32822957 G/A cg02381751 chr2:32503542 YIPF4 0.46 5.97 0.31 6.03e-9 Interleukin-18 levels; LIHC cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg23758822 chr17:41437982 NA 0.96 18.39 0.71 5.32e-53 Menopause (age at onset); LIHC cis rs9911578 0.967 rs9894274 chr17:56977919 G/A cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs172166 0.694 rs1150666 chr6:28123928 T/C cg25329415 chr6:28076851 NA 0.27 5.81 0.3 1.46e-8 Cardiac Troponin-T levels; LIHC cis rs769267 1.000 rs7246748 chr19:19433105 C/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.39 -0.33 5.54e-10 Tonsillectomy; LIHC cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg20684491 chr1:25596433 NA -0.29 -6.04 -0.31 3.97e-9 Erythrocyte sedimentation rate; LIHC cis rs950776 0.593 rs601079 chr15:78869579 T/A cg06917634 chr15:78832804 PSMA4 -0.63 -8.58 -0.42 3.37e-16 Sudden cardiac arrest; LIHC cis rs10504229 0.565 rs7010503 chr8:58147127 G/A cg21448741 chr8:58168803 NA 0.32 6.03 0.31 4.14e-9 Developmental language disorder (linguistic errors); LIHC cis rs9325144 0.768 rs11168750 chr12:38992710 C/A cg26384229 chr12:38710491 ALG10B -0.42 -5.83 -0.3 1.26e-8 Morning vs. evening chronotype; LIHC cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg12751644 chr20:60527061 NA -0.52 -8.76 -0.43 8.89e-17 Obesity-related traits; LIHC cis rs9640161 0.789 rs6964110 chr7:150041836 A/C cg17279839 chr7:150038598 RARRES2 0.54 11.85 0.54 2.27e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs9534288 0.751 rs2806920 chr13:46514506 T/C cg15192986 chr13:46630673 CPB2 0.54 7.62 0.38 2.47e-13 Blood protein levels; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg22528358 chr1:107598549 PRMT6 -0.63 -9.58 -0.46 2.13e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2274273 0.714 rs7154889 chr14:55806885 G/A cg01864836 chr14:55583639 NA -0.4 -7.48 -0.38 6.21e-13 Protein biomarker; LIHC cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg10360323 chr17:41437877 NA 0.41 6.04 0.31 4.09e-9 Menopause (age at onset); LIHC cis rs8044995 0.501 rs73613999 chr16:68390099 C/A cg05110241 chr16:68378359 PRMT7 -0.84 -9.59 -0.46 1.92e-19 Schizophrenia; LIHC trans rs875971 0.838 rs2173570 chr7:65762963 T/A cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.18e-10 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13867718 chr16:29973267 TMEM219 0.43 6.17 0.32 1.94e-9 Pancreatic cancer; LIHC cis rs7520050 0.966 rs1707340 chr1:46514942 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.84 0.3 1.24e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg09033563 chr22:24373618 LOC391322 -0.46 -6.44 -0.33 3.96e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs763121 0.853 rs6001191 chr22:39074452 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs1670533 1.000 rs935970 chr4:1045323 C/G cg27284194 chr4:1044797 NA -0.52 -7.53 -0.38 4.53e-13 Recombination rate (females); LIHC cis rs6964587 0.869 rs7810391 chr7:91520227 G/A cg17063962 chr7:91808500 NA -0.98 -18.28 -0.7 1.42e-52 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02047359 chr10:75174015 ANXA7 0.41 6.67 0.34 1.05e-10 Cognitive function; LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg26338869 chr17:61819248 STRADA 0.61 8.91 0.43 3.16e-17 Prudent dietary pattern; LIHC trans rs2744203 1.000 rs72610884 chr6:104643279 T/C cg27088726 chr16:83171155 CDH13 -0.46 -6.08 -0.31 3.14e-9 IgG glycosylation; LIHC cis rs10857712 0.754 rs7921041 chr10:135229239 G/C cg15472797 chr10:135243109 NA -0.39 -5.93 -0.31 7.49e-9 Systemic lupus erythematosus; LIHC trans rs2727020 0.563 rs10769582 chr11:49474040 T/C cg18944383 chr4:111397179 ENPEP 0.24 6.15 0.32 2.17e-9 Coronary artery disease; LIHC cis rs57502260 0.704 rs12286536 chr11:68290234 C/G cg20283391 chr11:68216788 NA -0.5 -6.06 -0.31 3.57e-9 Total body bone mineral density (age 45-60); LIHC cis rs7635838 0.892 rs3942925 chr3:11442921 T/C cg00170343 chr3:11313890 ATG7 0.42 6.49 0.33 3.09e-10 HDL cholesterol; LIHC cis rs2295359 1.000 rs963427 chr1:67609347 A/G cg12940439 chr1:67600707 NA 0.4 7.33 0.37 1.67e-12 Psoriasis; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg12064134 chr16:90016061 DEF8 -0.46 -6.11 -0.31 2.78e-9 Skin colour saturation; LIHC cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.64 -0.38 2.15e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs9394841 0.692 rs13193235 chr6:41792659 T/C cg08135965 chr6:41755394 TOMM6 0.45 5.97 0.31 6.1e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg15585264 chr19:41770827 HNRNPUL1 -0.54 -6.53 -0.33 2.38e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs9534288 0.956 rs962694 chr13:46619026 T/C cg15192986 chr13:46630673 CPB2 -0.57 -8.49 -0.42 6.39e-16 Blood protein levels; LIHC trans rs8002861 0.967 rs9533689 chr13:44480413 A/C cg17145862 chr1:211918768 LPGAT1 0.67 13.33 0.58 6.19e-33 Leprosy; LIHC cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC cis rs4654899 0.601 rs6668094 chr1:21464387 C/T cg08539965 chr1:21396338 EIF4G3 -0.32 -5.77 -0.3 1.77e-8 Superior frontal gyrus grey matter volume; LIHC cis rs2066819 0.818 rs703830 chr12:56701872 T/C cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Psoriasis vulgaris; LIHC cis rs963731 0.649 rs78905728 chr2:39339241 G/T cg04010122 chr2:39346883 SOS1 0.68 6.06 0.31 3.6e-9 Corticobasal degeneration; LIHC cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.4e-30 Menopause (age at onset); LIHC trans rs2727020 0.553 rs4103567 chr11:49255389 C/T cg03929089 chr4:120376271 NA -0.5 -8.05 -0.4 1.39e-14 Coronary artery disease; LIHC cis rs9399135 1.000 rs4475342 chr6:135283348 T/C cg22676075 chr6:135203613 NA 0.38 6.24 0.32 1.29e-9 Red blood cell count; LIHC cis rs4073582 0.595 rs801737 chr11:65928193 T/C cg16950941 chr11:66035639 RAB1B 0.53 8.06 0.4 1.31e-14 Gout; LIHC cis rs1008375 1.000 rs56308330 chr4:17643050 G/A cg04450456 chr4:17643702 FAM184B 0.34 5.75 0.3 2.02e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8017423 0.967 rs11621431 chr14:90709221 C/T cg04374321 chr14:90722782 PSMC1 0.75 14.46 0.62 2.57e-37 Mortality in heart failure; LIHC cis rs17818399 0.815 rs17819022 chr2:46850571 G/A cg02822958 chr2:46747628 ATP6V1E2 0.39 5.78 0.3 1.68e-8 Height; LIHC cis rs4908760 0.965 rs10864356 chr1:8569871 A/T cg20416874 chr1:8611966 RERE -0.68 -14.62 -0.62 6.36e-38 Vitiligo; LIHC cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg07424592 chr7:64974309 NA 0.75 8.79 0.43 7.66e-17 Diabetic kidney disease; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg00280220 chr17:61926910 NA 0.43 6.87 0.35 3.04e-11 Prudent dietary pattern; LIHC cis rs9549367 0.789 rs7994324 chr13:113906497 T/C cg00898013 chr13:113819073 PROZ -0.42 -7.17 -0.36 4.71e-12 Platelet distribution width; LIHC cis rs17685 0.775 rs11761172 chr7:75761547 C/T cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1707322 0.716 rs6699444 chr1:46135120 G/C cg06784218 chr1:46089804 CCDC17 0.41 7.49 0.38 5.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10489202 1.000 rs17485889 chr1:168018840 G/T cg24449463 chr1:168025552 DCAF6 -0.52 -6.47 -0.33 3.3e-10 Schizophrenia; LIHC cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg03806693 chr22:41940476 POLR3H -1.0 -10.13 -0.48 2.84e-21 Vitiligo; LIHC trans rs208520 1.000 rs12199876 chr6:66989469 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.03 0.36 1.11e-11 Exhaled nitric oxide output; LIHC cis rs903552 0.736 rs9806369 chr15:102008430 A/C cg04789225 chr15:102009795 PCSK6 -0.47 -6.22 -0.32 1.45e-9 Diabetic kidney disease; LIHC cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg18305652 chr10:134549665 INPP5A 0.5 7.89 0.39 4.16e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11958404 0.615 rs7724696 chr5:157450852 A/C cg05962755 chr5:157440814 NA 0.59 7.83 0.39 6.15e-14 IgG glycosylation; LIHC cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -11.15 -0.52 7.8e-25 Platelet count; LIHC cis rs3112357 0.951 rs3112348 chr7:135387953 A/G cg20392616 chr7:135392013 SLC13A4 0.41 6.81 0.35 4.32e-11 Plantar warts; LIHC cis rs17826219 0.636 rs4055314 chr17:29079769 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.03 0.4 1.55e-14 Body mass index; LIHC trans rs1493916 0.777 rs1845385 chr18:31318336 T/C cg27147174 chr7:100797783 AP1S1 -0.49 -6.86 -0.35 3.31e-11 Life satisfaction; LIHC trans rs35668226 1.000 rs35668226 chr10:122849667 A/G cg08474467 chr16:593365 SOLH 0.41 6.04 0.31 4e-9 Type 2 diabetes; LIHC cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg21294424 chr19:58662284 ZNF329 0.93 7.26 0.37 2.55e-12 Cholesterol, total; LIHC cis rs2257205 0.667 rs7213035 chr17:56857281 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.61 -0.34 1.5e-10 Pancreatic cancer; LIHC cis rs600806 0.778 rs10745357 chr1:110001876 G/C cg08911820 chr1:110026001 ATXN7L2 -0.66 -8.07 -0.4 1.19e-14 Intelligence (multi-trait analysis); LIHC cis rs735396 0.627 rs2264778 chr12:121450354 C/A cg15155738 chr12:121454335 C12orf43 0.54 7.76 0.39 9.67e-14 N-glycan levels; LIHC cis rs2070488 0.804 rs13092539 chr3:38458725 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.28 0.55 5.77e-29 Electrocardiographic conduction measures; LIHC cis rs7617773 0.638 rs7644414 chr3:48299079 A/T cg11946769 chr3:48343235 NME6 0.77 9.48 0.46 4.33e-19 Coronary artery disease; LIHC cis rs1707322 0.963 rs10890371 chr1:46390897 T/G cg06784218 chr1:46089804 CCDC17 0.34 6.03 0.31 4.19e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3770081 1.000 rs3770082 chr2:86280922 T/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.85 -8.88 -0.43 3.77e-17 Facial emotion recognition (sad faces); LIHC trans rs2727020 0.857 rs1917324 chr11:49371759 G/C cg18944383 chr4:111397179 ENPEP 0.28 6.46 0.33 3.54e-10 Coronary artery disease; LIHC cis rs10791097 0.694 rs7940027 chr11:130745591 A/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg11070056 chr1:107600091 PRMT6 -0.63 -10.52 -0.49 1.34e-22 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs8044868 0.530 rs8060770 chr16:72155694 C/A cg16558253 chr16:72132732 DHX38 -0.38 -6.43 -0.33 4.3e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs2749592 0.531 rs1208559 chr10:38221370 T/C cg03665457 chr10:38645376 HSD17B7P2 0.4 5.91 0.3 8.16e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3892630 0.619 rs61062732 chr19:33304717 T/C cg22980127 chr19:33182716 NUDT19 1.01 13.1 0.58 4.75e-32 Red blood cell traits; LIHC cis rs7772486 0.754 rs9497434 chr6:146260753 C/T cg23711669 chr6:146136114 FBXO30 -0.71 -12.5 -0.56 8.37e-30 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10490227 chr1:40348903 TRIT1 0.45 6.66 0.34 1.1e-10 Lung function (FEV1/FVC); LIHC cis rs7116495 0.609 rs949324 chr11:71714526 G/C cg26138937 chr11:71823887 C11orf51 -1.25 -10.59 -0.5 7.2e-23 Severe influenza A (H1N1) infection; LIHC cis rs2274273 0.805 rs60972460 chr14:55571773 A/T cg01864836 chr14:55583639 NA -0.44 -8.63 -0.42 2.36e-16 Protein biomarker; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07792822 chr1:157961914 KIRREL 0.42 7.16 0.36 5.06e-12 Pancreatic cancer; LIHC cis rs6754311 0.773 rs309180 chr2:136614255 A/G cg25344623 chr2:136566232 LCT -0.4 -8.36 -0.41 1.61e-15 Mosquito bite size; LIHC cis rs2180341 0.960 rs9398840 chr6:127669744 G/A cg24812749 chr6:127587940 RNF146 1.05 15.38 0.64 6.23e-41 Breast cancer; LIHC cis rs35306767 0.903 rs1341741 chr10:888073 A/G cg26597838 chr10:835615 NA 1.11 13.81 0.6 9.05e-35 Eosinophil percentage of granulocytes; LIHC cis rs116095464 0.558 rs10462755 chr5:246748 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.68 -0.5 3.47e-23 Breast cancer; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg12016809 chr21:47604291 C21orf56 0.46 6.99 0.35 1.49e-11 Testicular germ cell tumor; LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg04025307 chr7:1156635 C7orf50 0.57 10.05 0.48 5.41e-21 Longevity;Endometriosis; LIHC trans rs875971 0.660 rs801193 chr7:66030612 A/C cg26939375 chr7:64535504 NA -0.41 -6.74 -0.34 6.73e-11 Aortic root size; LIHC cis rs2153535 0.580 rs2327064 chr6:8454052 C/T cg21535247 chr6:8435926 SLC35B3 0.65 8.56 0.42 3.8e-16 Motion sickness; LIHC cis rs9814567 0.806 rs4955525 chr3:134317008 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.45 -0.46 5.53e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9467773 1.000 rs9986382 chr6:26550619 T/C cg11502198 chr6:26597334 ABT1 0.45 6.64 0.34 1.21e-10 Intelligence (multi-trait analysis); LIHC cis rs801193 0.839 rs12534943 chr7:66070520 A/G cg18876405 chr7:65276391 NA -0.41 -7.33 -0.37 1.66e-12 Aortic root size; LIHC trans rs35333254 1.000 rs35333254 chr4:14438810 A/G cg20299935 chr17:21795943 NA -0.54 -6.56 -0.33 2.02e-10 Age-related hearing impairment; LIHC trans rs1945213 0.659 rs2086558 chr11:55844453 T/G cg15704280 chr7:45808275 SEPT13 0.59 7.58 0.38 3.25e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs1728785 0.901 rs1170437 chr16:68607943 C/T cg02972257 chr16:68554789 NA -0.52 -5.83 -0.3 1.32e-8 Ulcerative colitis; LIHC cis rs9467773 1.000 rs2208331 chr6:26507319 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.85 0.6 6.03e-35 Intelligence (multi-trait analysis); LIHC cis rs1775715 0.870 rs1775737 chr10:32256871 T/C cg14930904 chr10:32216787 ARHGAP12 0.38 6.83 0.35 3.99e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg02993280 chr1:107599747 PRMT6 -0.58 -9.04 -0.44 1.17e-17 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3796352 0.764 rs34872575 chr3:52986277 G/A cg07884673 chr3:53033167 SFMBT1 0.89 6.49 0.33 3.1e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs5753618 0.583 rs7287267 chr22:31748415 C/T cg07713946 chr22:31675144 LIMK2 0.31 6.05 0.31 3.76e-9 Colorectal cancer; LIHC cis rs7927771 0.965 rs35985502 chr11:47847428 G/A cg20135002 chr11:47629003 NA -0.53 -9.01 -0.44 1.47e-17 Subjective well-being; LIHC cis rs3806843 0.838 rs2262567 chr5:140132134 T/A cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1639906 0.729 rs17186614 chr7:2231002 G/A cg02951883 chr7:2050386 MAD1L1 0.58 7.56 0.38 3.81e-13 Colonoscopy-negative controls vs population controls; LIHC trans rs78049276 0.688 rs80157433 chr4:148370548 A/G cg13149281 chr14:23389818 RBM23;PRMT5 -0.62 -7.66 -0.38 1.97e-13 Pulse pressure; LIHC trans rs9956878 0.555 rs8085188 chr18:73544676 A/G cg17608500 chr1:154955711 FLAD1 0.42 6.5 0.33 2.9e-10 Obesity-related traits; LIHC cis rs1144333 0.510 rs1250882 chr1:76287314 C/A cg03433033 chr1:76189801 ACADM -0.53 -7.42 -0.37 9.61e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.71 11.61 0.53 1.63e-26 Height; LIHC cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg11764359 chr7:65958608 NA 0.56 5.99 0.31 5.28e-9 Diabetic kidney disease; LIHC cis rs7408868 1.000 rs2074618 chr19:15276143 C/T cg09752223 chr19:15281200 NOTCH3 -0.37 -5.86 -0.3 1.07e-8 Pulse pressure; LIHC cis rs2806561 0.734 rs11578046 chr1:23425139 G/A cg12483005 chr1:23474871 LUZP1 0.48 7.38 0.37 1.18e-12 Height; LIHC cis rs17711722 0.690 rs116823227 chr7:65331001 A/G cg14393609 chr7:65229607 NA 0.42 5.73 0.3 2.19e-8 Calcium levels; LIHC cis rs6450176 0.625 rs67656636 chr5:53288455 C/A ch.5.1024479R chr5:53302184 ARL15 -0.88 -16.25 -0.66 2.14e-44 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs921968 0.643 rs483172 chr2:219428299 A/G cg18887096 chr2:219472410 PLCD4 0.36 6.36 0.33 6.49e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs4253772 0.513 rs6008700 chr22:46722560 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.8 7.18 0.36 4.34e-12 LDL cholesterol;Cholesterol, total; LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs986417 1.000 rs958504 chr14:60949740 G/A cg27398547 chr14:60952738 C14orf39 0.83 9.57 0.46 2.19e-19 Gut microbiota (bacterial taxa); LIHC cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.16 -0.44 4.95e-18 Bipolar disorder; LIHC cis rs9911578 0.835 rs9303398 chr17:56484257 T/C cg12560992 chr17:57184187 TRIM37 -0.9 -15.04 -0.63 1.4e-39 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17630771 chr11:101981004 YAP1 0.49 6.88 0.35 2.82e-11 Lung function (FEV1/FVC); LIHC cis rs6815814 0.950 rs11727978 chr4:38811051 T/A cg06935464 chr4:38784597 TLR10 0.46 7.19 0.36 4.1e-12 Breast cancer; LIHC trans rs1432089 0.773 rs62344304 chr4:171786925 C/A cg02328223 chr3:127541927 MGLL -0.42 -6.09 -0.31 3.09e-9 Endometriosis; LIHC trans rs9929218 0.954 rs34530130 chr16:68827620 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.1 -0.4 9.58e-15 Colorectal cancer; LIHC cis rs10883723 0.810 rs7094366 chr10:104274730 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.48 0.56 1.04e-29 Allergic disease (asthma, hay fever or eczema); LIHC cis rs8017423 0.967 rs61231898 chr14:90691696 G/A cg14092571 chr14:90743983 NA -0.37 -5.79 -0.3 1.59e-8 Mortality in heart failure; LIHC cis rs10878977 0.565 rs6581891 chr12:69813215 T/C cg17330252 chr12:69809627 NA 0.38 5.99 0.31 5.44e-9 Colorectal cancer; LIHC cis rs1401999 0.659 rs4912518 chr3:183752027 C/T cg01324343 chr3:183735012 ABCC5 -0.77 -12.01 -0.54 5.95e-28 Anterior chamber depth; LIHC cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg26939375 chr7:64535504 NA 0.47 7.12 0.36 6.39e-12 Aortic root size; LIHC cis rs1005277 0.579 rs1985707 chr10:38434098 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs6701037 1.000 rs1057305 chr1:175126223 T/A cg17845761 chr1:175162550 KIAA0040 -0.36 -5.89 -0.3 9.17e-9 Alcohol dependence; LIHC cis rs2404602 0.692 rs58361452 chr15:76973372 T/C cg03037974 chr15:76606532 NA 0.74 14.47 0.62 2.41e-37 Blood metabolite levels; LIHC cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg25072359 chr17:41440525 NA 0.39 6.12 0.31 2.58e-9 Menopause (age at onset); LIHC cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg17179660 chr6:151773299 C6orf211;RMND1 -0.39 -5.96 -0.31 6.24e-9 Menarche (age at onset); LIHC cis rs2073300 1.000 rs6114135 chr20:23456746 C/A cg12062639 chr20:23401060 NAPB 0.75 9.04 0.44 1.2e-17 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17401966 0.838 rs12737239 chr1:10323973 C/G cg19773385 chr1:10388646 KIF1B -0.4 -7.25 -0.36 2.89e-12 Hepatocellular carcinoma; LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg00106254 chr7:1943704 MAD1L1 -0.48 -8.01 -0.4 1.84e-14 Bipolar disorder and schizophrenia; LIHC trans rs9926296 0.618 rs8058179 chr16:89846987 C/T cg14170313 chr9:77112896 RORB -0.5 -6.42 -0.33 4.55e-10 Vitiligo; LIHC cis rs9326248 0.953 rs488962 chr11:117072525 C/T cg01368799 chr11:117014884 PAFAH1B2 -0.41 -5.81 -0.3 1.46e-8 Blood protein levels; LIHC cis rs9640161 0.658 rs60467296 chr7:150015471 G/A cg10018233 chr7:150070692 REPIN1 0.5 8.43 0.41 9.5e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs35110281 0.713 rs6518310 chr21:45098670 T/A cg21573476 chr21:45109991 RRP1B -0.56 -10.61 -0.5 6.25e-23 Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03925809 chr19:6393419 GTF2F1 0.46 6.8 0.35 4.72e-11 Pancreatic cancer; LIHC cis rs2857078 0.745 rs4793085 chr17:42320732 A/C cg09913183 chr17:42254507 C17orf65;ASB16 -0.68 -9.92 -0.47 1.53e-20 Red cell distribution width;Reticulocyte count; LIHC cis rs8180040 0.522 rs749512 chr3:47035900 C/T cg27129171 chr3:47204927 SETD2 -0.51 -8.09 -0.4 1.04e-14 Colorectal cancer; LIHC cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg20607798 chr8:58055168 NA 0.65 7.65 0.38 2.05e-13 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.691 rs12502524 chr4:120271414 G/A cg09307838 chr4:120376055 NA 0.62 9.83 0.47 3e-20 Corneal astigmatism; LIHC cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg06640241 chr16:89574553 SPG7 0.88 16.67 0.67 4.28e-46 Multiple myeloma (IgH translocation); LIHC trans rs1005277 0.529 rs1780125 chr10:38531376 A/G cg17830980 chr10:43048298 ZNF37B -0.49 -9.44 -0.45 5.8e-19 Extrinsic epigenetic age acceleration; LIHC cis rs918629 0.530 rs3815768 chr5:95236459 C/T cg10483112 chr5:95245456 ELL2 -0.37 -6.76 -0.34 5.99e-11 IgG glycosylation; LIHC cis rs7582180 0.627 rs4149523 chr2:101007039 T/C cg14675211 chr2:100938903 LONRF2 0.56 8.27 0.41 3.07e-15 Intelligence (multi-trait analysis); LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg07167872 chr1:205819463 PM20D1 0.61 8.78 0.43 8.21e-17 Menarche (age at onset); LIHC cis rs921968 0.541 rs581013 chr2:219432040 G/T cg02985541 chr2:219472218 PLCD4 0.42 6.84 0.35 3.73e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs1046896 0.627 rs7225515 chr17:80795783 C/T cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.5 0.38 5.65e-13 Glycated hemoglobin levels; LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg20607798 chr8:58055168 NA 0.66 8.28 0.41 2.74e-15 Developmental language disorder (linguistic errors); LIHC cis rs739401 0.611 rs7130841 chr11:3043658 A/G cg20651018 chr11:3035856 CARS -0.35 -5.88 -0.3 1e-8 Longevity; LIHC trans rs9956878 0.555 rs8085188 chr18:73544676 A/G cg23260799 chr11:451101 PTDSS2 0.4 6.11 0.31 2.74e-9 Obesity-related traits; LIHC cis rs2370759 1.000 rs77165999 chr10:32577131 T/C cg01819863 chr10:32635814 EPC1 1.11 16.42 0.66 4.34e-45 Sexual dysfunction (female); LIHC cis rs7107174 0.792 rs2888465 chr11:77945807 T/C cg02023728 chr11:77925099 USP35 0.5 9.4 0.45 8.12e-19 Testicular germ cell tumor; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06811360 chr17:8089327 NA 0.44 6.09 0.31 3e-9 Pancreatic cancer; LIHC cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg12756686 chr19:29218302 NA 0.44 6.44 0.33 4.13e-10 Methadone dose in opioid dependence; LIHC cis rs35146811 0.844 rs59261051 chr7:99650429 C/T cg22906224 chr7:99728672 NA 0.45 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs7927592 0.830 rs10896339 chr11:68302846 G/C cg01657329 chr11:68192670 LRP5 -0.47 -6.26 -0.32 1.16e-9 Total body bone mineral density; LIHC cis rs1371867 0.810 rs2860518 chr8:101238120 G/T cg06002616 chr8:101225028 SPAG1 0.34 5.83 0.3 1.29e-8 Atrioventricular conduction; LIHC cis rs2115536 0.692 rs6495451 chr15:80164053 C/T cg11839771 chr15:80205821 ST20 -0.32 -6.99 -0.35 1.45e-11 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs7587476 1.000 rs1542173 chr2:215657560 C/T cg04004882 chr2:215674386 BARD1 -0.52 -6.93 -0.35 2.12e-11 Neuroblastoma; LIHC trans rs35110281 0.782 rs2838329 chr21:45023329 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.11 0.31 2.7e-9 Mean corpuscular volume; LIHC cis rs7542091 0.704 rs1108628 chr1:210041150 A/G cg22029157 chr1:209979665 IRF6 0.37 6.24 0.32 1.27e-9 Monobrow; LIHC cis rs6442522 0.966 rs3856828 chr3:15488997 T/C cg16303742 chr3:15540471 COLQ 0.46 7.61 0.38 2.61e-13 Uric acid levels; LIHC cis rs8044995 0.563 rs56220628 chr16:68384837 G/A cg09835421 chr16:68378352 PRMT7 -0.8 -9.47 -0.46 4.73e-19 Schizophrenia; LIHC cis rs6669919 0.553 rs12568639 chr1:211675300 G/A cg10512769 chr1:211675356 NA -0.3 -5.87 -0.3 1.03e-8 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.505 rs1335629 chr6:8491863 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14497545 chr4:140754475 MAML3 -0.62 -9.01 -0.44 1.48e-17 Lung function (FEV1/FVC); LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg13126279 chr21:47581558 C21orf56 0.44 7.22 0.36 3.46e-12 Testicular germ cell tumor; LIHC cis rs12220238 1.000 rs11000930 chr10:75982982 C/G cg19889307 chr10:75911429 ADK;AP3M1 -0.71 -6.58 -0.34 1.76e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs4555082 0.874 rs2816611 chr14:105722976 G/C cg13114125 chr14:105738426 BRF1 -0.69 -9.18 -0.44 4.15e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs17818399 0.888 rs2346419 chr2:46845069 G/C cg02822958 chr2:46747628 ATP6V1E2 0.45 6.9 0.35 2.47e-11 Height; LIHC cis rs12477438 0.520 rs34766932 chr2:99737273 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.19 21.27 0.75 1.51e-64 Chronic sinus infection; LIHC cis rs9393777 0.588 rs11967935 chr6:26560672 A/C cg12826209 chr6:26865740 GUSBL1 0.54 6.3 0.32 9.21e-10 Intelligence (multi-trait analysis); LIHC trans rs9929218 1.000 rs12446407 chr16:68804068 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.78 -0.43 8.25e-17 Colorectal cancer; LIHC cis rs7296418 0.699 rs11057254 chr12:123794581 A/C cg00376283 chr12:123451042 ABCB9 0.61 10.2 0.48 1.69e-21 Platelet count; LIHC cis rs1797081 1.000 rs2603807 chr10:16872797 A/G cg23933602 chr10:16859644 RSU1 0.99 19.41 0.72 4.04e-57 Platelet distribution width; LIHC cis rs7208859 0.623 rs7208088 chr17:29143667 C/T cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs208520 0.955 rs208538 chr6:66964492 C/G cg07460842 chr6:66804631 NA -0.65 -6.99 -0.35 1.44e-11 Exhaled nitric oxide output; LIHC cis rs7534824 0.543 rs61780300 chr1:101403601 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 7.66 0.38 1.97e-13 Refractive astigmatism; LIHC cis rs10823500 0.640 rs7077538 chr10:71993094 T/G cg04118878 chr10:71993077 PPA1 0.59 6.59 0.34 1.71e-10 Blood protein levels; LIHC cis rs7945705 0.791 rs12421789 chr11:8813956 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.39 -6.87 -0.35 3.09e-11 Hemoglobin concentration; LIHC cis rs2842992 0.789 rs2295901 chr6:160201295 C/A cg11366901 chr6:160182831 ACAT2 0.9 15.31 0.64 1.17e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs7647973 0.925 rs4955439 chr3:49245645 G/T cg07636037 chr3:49044803 WDR6 -0.5 -6.15 -0.32 2.2e-9 Menarche (age at onset); LIHC cis rs34779708 0.966 rs10827493 chr10:35454976 C/T cg04310649 chr10:35416472 CREM -0.43 -5.85 -0.3 1.13e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs798554 0.610 rs2248390 chr7:2855594 T/C cg19717773 chr7:2847554 GNA12 -0.42 -7.5 -0.38 5.67e-13 Height; LIHC cis rs7909074 1.000 rs4948926 chr10:45392604 G/C cg05187965 chr10:45406764 TMEM72 -0.28 -6.98 -0.35 1.56e-11 Mean corpuscular volume; LIHC cis rs68170813 0.559 rs2107319 chr7:106863744 T/C cg02696742 chr7:106810147 HBP1 -0.53 -6.22 -0.32 1.48e-9 Coronary artery disease; LIHC cis rs9633740 0.545 rs2343306 chr10:82230146 A/G cg00277334 chr10:82204260 NA 0.52 6.12 0.31 2.61e-9 Post bronchodilator FEV1; LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg21747090 chr2:27597821 SNX17 -0.43 -6.36 -0.33 6.46e-10 Total body bone mineral density; LIHC cis rs651907 0.557 rs11917569 chr3:101355063 G/C cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.12 -0.31 2.62e-9 Colorectal cancer; LIHC cis rs986417 0.818 rs4901993 chr14:61081453 G/A cg27398547 chr14:60952738 C14orf39 0.65 7.22 0.36 3.45e-12 Gut microbiota (bacterial taxa); LIHC cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs17152411 0.652 rs3740535 chr10:126676686 T/C cg07906193 chr10:126599966 NA -0.29 -5.81 -0.3 1.47e-8 Height; LIHC cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg03264133 chr6:25882463 NA -0.53 -7.6 -0.38 2.95e-13 Blood metabolite levels; LIHC cis rs796364 0.806 rs79333757 chr2:200915716 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs7474896 0.559 rs2753880 chr10:38173338 G/A cg25427524 chr10:38739819 LOC399744 0.46 5.92 0.3 7.9e-9 Obesity (extreme); LIHC trans rs208520 1.000 rs208527 chr6:66957209 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.69 -0.34 9.29e-11 Exhaled nitric oxide output; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.04e-14 Height; LIHC cis rs16854884 0.657 rs34683397 chr3:143723559 C/T cg06585982 chr3:143692056 C3orf58 0.47 5.8 0.3 1.49e-8 Economic and political preferences (feminism/equality); LIHC cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.4 0.45 8.18e-19 Platelet count; LIHC cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.59 0.34 1.66e-10 Bipolar disorder; LIHC cis rs6860806 0.507 rs582490 chr5:131710095 G/A cg24060327 chr5:131705240 SLC22A5 0.79 12.43 0.56 1.53e-29 Breast cancer; LIHC cis rs7107174 0.901 rs2450139 chr11:77924544 G/A cg02023728 chr11:77925099 USP35 0.48 9.35 0.45 1.17e-18 Testicular germ cell tumor; LIHC cis rs6466055 0.932 rs2057883 chr7:104929837 C/G cg04380332 chr7:105027541 SRPK2 0.34 6.4 0.33 5.02e-10 Schizophrenia; LIHC cis rs4474465 0.915 rs11237505 chr11:78171261 A/G cg02023728 chr11:77925099 USP35 0.32 5.82 0.3 1.34e-8 Alzheimer's disease (survival time); LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg21747090 chr2:27597821 SNX17 -0.43 -6.55 -0.33 2.15e-10 Total body bone mineral density; LIHC cis rs561341 0.609 rs739800 chr17:30190083 T/A cg13647721 chr17:30228624 UTP6 -0.69 -7.11 -0.36 6.92e-12 Hip circumference adjusted for BMI; LIHC cis rs875971 0.862 rs10274883 chr7:66116091 C/T cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg06212747 chr3:49208901 KLHDC8B 0.63 8.59 0.42 3.14e-16 Menarche (age at onset); LIHC cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg26752003 chr8:145688521 CYHR1 -0.48 -7.55 -0.38 3.88e-13 Age at first birth; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.71 11.59 0.53 1.98e-26 Prudent dietary pattern; LIHC cis rs10870270 1.000 rs10870292 chr10:133770782 G/C cg17892150 chr10:133769511 PPP2R2D -0.66 -12.16 -0.55 1.68e-28 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs3096299 0.802 rs3102336 chr16:89442006 C/T cg02187348 chr16:89574699 SPG7 0.4 5.72 0.3 2.34e-8 Multiple myeloma (IgH translocation); LIHC cis rs929354 0.742 rs3808316 chr7:156944787 C/G cg05182265 chr7:156933206 UBE3C -0.31 -5.95 -0.31 6.74e-9 Body mass index; LIHC cis rs78456975 0.941 rs28913033 chr2:1523194 T/C cg01028140 chr2:1542097 TPO -0.57 -6.32 -0.32 8.08e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs965469 1.000 rs6037567 chr20:3332160 C/A cg25506879 chr20:3388711 C20orf194 -0.58 -6.98 -0.35 1.59e-11 IFN-related cytopenia; LIHC trans rs67460515 0.529 rs6441364 chr3:160897915 A/C cg13973472 chr14:55032305 NA 0.4 6.43 0.33 4.39e-10 Parkinson's disease; LIHC cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg09222892 chr1:25734099 RHCE 0.48 8.98 0.44 1.82e-17 Erythrocyte sedimentation rate; LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg14709524 chr16:89940631 TCF25 0.59 7.74 0.39 1.14e-13 Skin colour saturation; LIHC cis rs1863824 0.625 rs10887598 chr10:88166160 T/A cg07322936 chr10:88137208 NA -0.47 -6.12 -0.31 2.51e-9 Schizophrenia; LIHC cis rs903552 1.000 rs8043205 chr15:102005749 A/G cg00659931 chr15:102010125 PCSK6 -0.46 -6.19 -0.32 1.7e-9 Diabetic kidney disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14561318 chr22:18507401 MICAL3 0.49 6.96 0.35 1.79e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7737355 0.947 rs31585 chr5:130999082 A/G cg06307176 chr5:131281290 NA 0.39 5.71 0.3 2.44e-8 Life satisfaction; LIHC cis rs4629710 0.617 rs28360555 chr6:131538952 C/A cg12606694 chr6:131520996 AKAP7 0.62 7.19 0.36 4.21e-12 Multiple myeloma (IgH translocation); LIHC cis rs6748734 0.553 rs7340215 chr2:241805851 A/G cg09990169 chr2:241835740 C2orf54 -0.44 -6.47 -0.33 3.38e-10 Urinary metabolites; LIHC cis rs4132509 0.744 rs12031994 chr1:243917309 T/C cg21452805 chr1:244014465 NA 0.45 5.78 0.3 1.66e-8 RR interval (heart rate); LIHC cis rs3812111 0.774 rs563176 chr6:116431426 C/A cg08036074 chr6:116424633 NT5DC1 0.66 11.74 0.54 5.72e-27 Age-related macular degeneration; LIHC cis rs4407350 0.870 rs5764873 chr22:44908153 G/A cg11695653 chr22:44894386 LDOC1L -0.35 -6.02 -0.31 4.45e-9 Intelligence (multi-trait analysis); LIHC cis rs6121246 0.909 rs6058450 chr20:30343911 G/A cg13852791 chr20:30311386 BCL2L1 0.95 9.7 0.46 8.02e-20 Mean corpuscular hemoglobin; LIHC cis rs597539 0.652 rs488363 chr11:68658298 C/G cg06028808 chr11:68637592 NA 0.44 5.78 0.3 1.7e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg26818010 chr10:134567672 INPP5A -0.79 -9.6 -0.46 1.81e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2625529 0.938 rs8747 chr15:72115541 C/A cg16672083 chr15:72433130 SENP8 -0.33 -6.14 -0.31 2.35e-9 Red blood cell count; LIHC cis rs7221595 0.825 rs10521127 chr17:3978268 A/G cg11204139 chr17:3907470 NA 0.53 7.05 0.36 9.93e-12 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; LIHC cis rs7523273 0.853 rs7537216 chr1:208006429 A/T cg22525895 chr1:207977042 MIR29B2 -0.69 -10.59 -0.5 7.74e-23 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07956936 chr16:72127419 TXNL4B;DHX38 0.48 7.26 0.37 2.67e-12 Cognitive function; LIHC cis rs35110281 0.748 rs1584918 chr21:45042419 C/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.58 -0.34 1.72e-10 Mean corpuscular volume; LIHC cis rs16958440 0.581 rs11872531 chr18:44689234 C/A cg17192377 chr18:44677553 HDHD2 0.71 7.79 0.39 8.32e-14 Sitting height ratio; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg21747090 chr2:27597821 SNX17 -0.43 -6.36 -0.33 6.46e-10 Total body bone mineral density; LIHC cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg15691649 chr6:25882328 NA -0.54 -7.82 -0.39 6.76e-14 Blood metabolite levels; LIHC cis rs986417 1.000 rs7160408 chr14:60977471 A/G cg27398547 chr14:60952738 C14orf39 0.76 8.36 0.41 1.61e-15 Gut microbiota (bacterial taxa); LIHC cis rs763121 0.853 rs2267394 chr22:39101633 T/C cg14440974 chr22:39074834 NA -0.37 -6.25 -0.32 1.21e-9 Menopause (age at onset); LIHC cis rs2559856 1.000 rs10860771 chr12:102087242 A/G cg12924262 chr12:102091054 CHPT1 0.53 8.5 0.42 5.98e-16 Blood protein levels; LIHC trans rs3858145 0.588 rs2305083 chr10:70044937 C/A cg04882175 chr6:131122610 NA -0.51 -6.08 -0.31 3.24e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs7208859 0.623 rs12006 chr17:29110652 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs57221529 0.766 rs12522140 chr5:587261 C/A cg09021430 chr5:549028 NA -0.45 -8.7 -0.43 1.45e-16 Lung disease severity in cystic fibrosis; LIHC cis rs13064411 0.696 rs35860985 chr3:113209828 C/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.15 0.55 1.69e-28 Height; LIHC cis rs6504663 0.558 rs7627 chr17:48552154 G/C cg00901687 chr17:48585270 MYCBPAP 0.45 6.39 0.33 5.4e-10 Visceral fat; LIHC cis rs7223966 1.000 rs9899491 chr17:61934384 G/C cg05941027 chr17:61774174 LIMD2 0.35 7.35 0.37 1.44e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6750047 0.546 rs985257 chr2:38283228 A/T cg07380506 chr2:38303506 CYP1B1 -0.64 -8.24 -0.41 3.67e-15 Cutaneous malignant melanoma;Melanoma; LIHC cis rs10870270 1.000 rs11146354 chr10:133774757 A/G cg08754478 chr10:133766260 PPP2R2D -0.56 -8.22 -0.41 4.17e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2295359 0.892 rs72676067 chr1:67658803 G/A cg12940439 chr1:67600707 NA 0.34 5.82 0.3 1.38e-8 Psoriasis; LIHC cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg08888203 chr3:10149979 C3orf24 0.54 6.27 0.32 1.06e-9 Alzheimer's disease; LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg12419862 chr22:24373484 LOC391322 -0.73 -11.15 -0.52 7.49e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg03264133 chr6:25882463 NA -0.68 -8.56 -0.42 3.91e-16 Intelligence (multi-trait analysis); LIHC trans rs783540 1.000 rs7496954 chr15:83345536 T/G cg18393722 chr15:85113863 UBE2QP1 0.4 6.93 0.35 2.11e-11 Schizophrenia; LIHC cis rs1555322 0.530 rs2425049 chr20:33874720 C/T cg07134254 chr20:33865797 NA 0.5 5.99 0.31 5.29e-9 Attention deficit hyperactivity disorder; LIHC cis rs35146811 0.555 rs2525539 chr7:99545309 A/G cg19636519 chr7:99541626 NA -0.31 -6.17 -0.32 1.93e-9 Coronary artery disease; LIHC cis rs769267 0.930 rs2304098 chr19:19646272 T/C cg03709012 chr19:19516395 GATAD2A 1.01 17.02 0.68 1.67e-47 Tonsillectomy; LIHC cis rs17401966 0.931 rs4846213 chr1:10399178 A/G cg15208524 chr1:10270712 KIF1B 0.42 6.22 0.32 1.43e-9 Hepatocellular carcinoma; LIHC cis rs11588062 0.628 rs11211270 chr1:46838986 C/T cg23431851 chr1:46668822 C1orf190;POMGNT1 0.43 6.86 0.35 3.16e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9649213 0.593 rs1132971 chr7:97921533 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.79 -0.3 1.61e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs6088590 1.000 rs2180276 chr20:33360785 T/A cg24642439 chr20:33292090 TP53INP2 0.79 11.34 0.52 1.64e-25 Coronary artery disease; LIHC cis rs561341 1.000 rs550923 chr17:30327013 G/C cg00745463 chr17:30367425 LRRC37B -0.77 -5.73 -0.3 2.16e-8 Hip circumference adjusted for BMI; LIHC cis rs4073582 0.595 rs801731 chr11:65938446 G/C cg16950941 chr11:66035639 RAB1B 0.55 8.39 0.41 1.3e-15 Gout; LIHC cis rs7647973 0.566 rs57630346 chr3:49086215 T/C cg07636037 chr3:49044803 WDR6 0.76 9.16 0.44 4.73e-18 Menarche (age at onset); LIHC cis rs950169 0.541 rs10795 chr15:85177297 G/A cg17507749 chr15:85114479 UBE2QP1 0.69 7.89 0.39 4.08e-14 Schizophrenia; LIHC cis rs6546550 0.933 rs1454498 chr2:70149225 C/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.54 -0.38 4.37e-13 Prevalent atrial fibrillation; LIHC cis rs12477438 0.700 rs10190421 chr2:99670711 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.67 -0.53 1.03e-26 Chronic sinus infection; LIHC cis rs875971 0.660 rs801190 chr7:66033033 C/T cg14393609 chr7:65229607 NA -0.37 -5.81 -0.3 1.4e-8 Aortic root size; LIHC cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg06238570 chr21:40685208 BRWD1 -0.39 -6.25 -0.32 1.25e-9 Menarche (age at onset); LIHC cis rs546131 0.928 rs572690 chr11:34833614 A/G cg11058730 chr11:34937778 PDHX;APIP 0.63 9.53 0.46 2.97e-19 Lung disease severity in cystic fibrosis; LIHC cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg27297192 chr10:134578999 INPP5A 0.53 7.42 0.37 9.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7119038 0.818 rs6589686 chr11:118612565 G/A cg19308663 chr11:118741387 NA 0.41 6.26 0.32 1.15e-9 Sjögren's syndrome; LIHC cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg00149659 chr3:10157352 C3orf10 0.7 7.1 0.36 7.09e-12 Alzheimer's disease; LIHC cis rs1113500 0.933 rs4590700 chr1:108638344 G/T cg06207961 chr1:108661230 NA 0.38 7.38 0.37 1.18e-12 Growth-regulated protein alpha levels; LIHC cis rs4423214 1.000 rs12785878 chr11:71167449 G/T cg05163923 chr11:71159392 DHCR7 0.88 13.69 0.59 2.55e-34 Vitamin D levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00780250 chr4:39979372 PDS5A -0.49 -6.67 -0.34 1.01e-10 Bilirubin levels; LIHC cis rs7927592 0.763 rs596494 chr11:68251054 T/G cg16797656 chr11:68205561 LRP5 0.53 9.42 0.45 6.92e-19 Total body bone mineral density; LIHC cis rs3782089 1.000 rs11600543 chr11:65298939 G/A cg08676812 chr11:65308423 LTBP3 1.05 7.32 0.37 1.84e-12 Height; LIHC cis rs7772486 0.625 rs9390355 chr6:146112942 C/T cg23711669 chr6:146136114 FBXO30 -0.72 -12.99 -0.57 1.23e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs4925386 1.000 rs4925386 chr20:60921044 C/T cg24112000 chr20:60950667 NA -0.43 -6.76 -0.34 5.81e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs1451375 0.617 rs11772714 chr7:50542843 G/A cg14593290 chr7:50529359 DDC -0.62 -10.06 -0.48 5.05e-21 Malaria; LIHC cis rs7131987 0.903 rs7302129 chr12:29415280 A/T cg16970926 chr12:29381810 FAR2 0.3 6.24 0.32 1.27e-9 QT interval; LIHC cis rs1538970 0.816 rs34673142 chr1:45985561 G/A cg24296786 chr1:45957014 TESK2 -0.49 -6.65 -0.34 1.15e-10 Platelet count; LIHC cis rs9649465 0.967 rs7791183 chr7:123343719 A/G cg03229431 chr7:123269106 ASB15 -0.37 -7.99 -0.4 2.04e-14 Migraine; LIHC cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.44 0.37 8.24e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7615952 0.932 rs13314869 chr3:125644669 G/A cg05084668 chr3:125655381 ALG1L -0.6 -8.55 -0.42 4.23e-16 Blood pressure (smoking interaction); LIHC cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg12463550 chr7:65579703 CRCP 0.68 7.3 0.37 2.02e-12 Diabetic kidney disease; LIHC cis rs10504073 0.584 rs10504070 chr8:49978554 A/G cg00325661 chr8:49890786 NA -0.33 -7.49 -0.38 5.8e-13 Blood metabolite ratios; LIHC trans rs8073060 0.561 rs225260 chr17:33958422 T/C cg19694781 chr19:47549865 TMEM160 -1.23 -13.15 -0.58 2.89e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs11722228 0.508 rs9732 chr4:10076658 T/C cg26043149 chr18:55253948 FECH 0.91 13.03 0.58 8.76e-32 Gout;Urate levels;Serum uric acid levels; LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg22907277 chr7:1156413 C7orf50 0.57 8.68 0.42 1.69e-16 Longevity;Endometriosis; LIHC cis rs6570726 0.846 rs371186 chr6:145886971 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.62 0.53 1.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9311474 0.632 rs6445528 chr3:52572447 C/T cg18404041 chr3:52824283 ITIH1 0.51 8.47 0.42 7.21e-16 Electroencephalogram traits; LIHC cis rs10489202 0.683 rs4657730 chr1:168072738 A/T cg24449463 chr1:168025552 DCAF6 -0.47 -6.57 -0.33 1.93e-10 Schizophrenia; LIHC cis rs1062753 0.771 rs5751245 chr22:42620940 T/C cg00645731 chr22:42541494 CYP2D7P1 0.37 6.21 0.32 1.54e-9 Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels); LIHC cis rs7845219 0.597 rs7002058 chr8:95873993 G/C cg09323728 chr8:95962352 TP53INP1 -0.28 -5.75 -0.3 1.96e-8 Type 2 diabetes; LIHC cis rs600806 0.683 rs10857789 chr1:110012293 C/T cg11161837 chr1:110010384 SYPL2 0.46 6.32 0.32 8.37e-10 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.44 6.11 0.31 2.7e-9 Electroencephalogram traits; LIHC cis rs896854 0.714 rs572547 chr8:95966286 A/G cg16049864 chr8:95962084 TP53INP1 0.59 9.77 0.47 4.76e-20 Type 2 diabetes; LIHC cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg09323728 chr8:95962352 TP53INP1 0.32 6.22 0.32 1.43e-9 Type 2 diabetes; LIHC cis rs1707322 0.964 rs785496 chr1:46588006 T/C cg03146154 chr1:46216737 IPP -0.46 -7.28 -0.37 2.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7909074 0.898 rs10793565 chr10:45388231 G/C cg04218760 chr10:45406644 TMEM72 -0.25 -7.95 -0.39 2.73e-14 Mean corpuscular volume; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg13012494 chr21:47604986 C21orf56 -0.38 -5.83 -0.3 1.31e-8 Testicular germ cell tumor; LIHC cis rs317689 0.702 rs544696 chr12:69749939 T/C cg19645103 chr12:69753606 YEATS4 -0.52 -7.54 -0.38 4.4e-13 Response to diuretic therapy; LIHC cis rs8017423 0.967 rs8015510 chr14:90729984 C/T cg04374321 chr14:90722782 PSMC1 0.78 15.26 0.64 1.75e-40 Mortality in heart failure; LIHC cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.06e-11 Alzheimer's disease; LIHC cis rs1801251 0.778 rs778340 chr2:233734083 C/T cg25237894 chr2:233734115 C2orf82 -0.6 -12.08 -0.55 3.12e-28 Coronary artery disease; LIHC trans rs3749237 0.964 rs2234385 chr3:49846041 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.63 9.65 0.46 1.24e-19 Resting heart rate; LIHC cis rs225245 0.765 rs226428 chr17:34049950 C/T cg05299278 chr17:33885742 SLFN14 -0.22 -6.08 -0.31 3.17e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs10088262 0.629 rs9918907 chr8:124816862 A/G cg02993010 chr8:124780839 FAM91A1 -0.46 -5.94 -0.31 6.99e-9 Pancreatic cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg15509053 chr7:123558137 NA 0.43 6.2 0.32 1.67e-9 Hepatitis; LIHC cis rs950776 0.518 rs12906951 chr15:78825562 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs769267 0.930 rs10414830 chr19:19562332 C/T cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.04 0.31 4.13e-9 Tonsillectomy; LIHC cis rs12477438 0.798 rs13412764 chr2:99583733 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.02 -0.51 2.28e-24 Chronic sinus infection; LIHC cis rs769267 0.930 rs1063966 chr19:19616742 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.0 0.31 5.11e-9 Tonsillectomy; LIHC trans rs61931739 0.500 rs7312938 chr12:34378708 C/T cg26384229 chr12:38710491 ALG10B 0.75 9.16 0.44 4.76e-18 Morning vs. evening chronotype; LIHC cis rs3791556 0.898 rs3828222 chr2:240109568 A/G cg03281426 chr2:240109471 HDAC4 -0.4 -6.56 -0.33 2.03e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs1728785 1.000 rs7195979 chr16:68586801 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.35 0.32 7.04e-10 Ulcerative colitis; LIHC cis rs3772130 0.564 rs35178434 chr3:121595936 G/A cg20356878 chr3:121714668 ILDR1 0.36 6.19 0.32 1.77e-9 Cognitive performance; LIHC cis rs950776 0.518 rs12907169 chr15:78825498 G/C cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs13191362 1.000 rs7764785 chr6:163009967 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2050392 0.517 rs302423 chr10:30772513 A/G cg25182066 chr10:30743637 MAP3K8 -0.64 -10.34 -0.49 5.72e-22 Inflammatory bowel disease; LIHC cis rs1580019 0.713 rs2167274 chr7:32524844 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.06 22.02 0.77 1.47e-67 Cognitive ability; LIHC cis rs7769051 1.000 rs12203977 chr6:133122760 A/G cg07930552 chr6:133119739 C6orf192 0.66 6.51 0.33 2.69e-10 Type 2 diabetes nephropathy; LIHC cis rs2288073 0.619 rs6713263 chr2:24375463 A/G cg06627628 chr2:24431161 ITSN2 -0.44 -6.48 -0.33 3.29e-10 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs6690583 0.524 rs12045710 chr1:85451765 T/C cg22153463 chr1:85462885 MCOLN2 0.52 6.22 0.32 1.42e-9 Serum sulfate level; LIHC cis rs1997103 0.906 rs2177806 chr7:55402609 A/T cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs17685 0.753 rs1637044 chr7:75703744 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1789 0.868 rs4631041 chr4:15673395 A/T cg21123203 chr4:15471301 CC2D2A -0.43 -6.78 -0.34 5.25e-11 Blood protein levels; LIHC cis rs853679 0.517 rs9393884 chr6:28046789 A/G cg23485639 chr6:28045615 ZNF165 0.43 5.73 0.3 2.21e-8 Depression; LIHC cis rs1023500 1.000 rs1047997 chr22:42334953 C/G cg04733989 chr22:42467013 NAGA -0.52 -6.1 -0.31 2.91e-9 Schizophrenia; LIHC cis rs2976388 0.573 rs1529865 chr8:143789171 C/T cg06565975 chr8:143823917 SLURP1 0.33 6.28 0.32 1.01e-9 Urinary tract infection frequency; LIHC cis rs17854409 0.803 rs1063246 chr20:61472116 G/A cg05147244 chr20:61493195 TCFL5 1.23 10.89 0.51 6.79e-24 Obesity-related traits; LIHC cis rs2070488 0.965 rs6599206 chr3:38545349 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.92 -15.67 -0.65 4.28e-42 Electrocardiographic conduction measures; LIHC cis rs10832963 1.000 rs7943121 chr11:18656062 G/C cg20219074 chr11:18656078 SPTY2D1 0.83 13.74 0.6 1.7e-34 Breast cancer; LIHC cis rs67460515 0.892 rs2100238 chr3:161058055 T/A cg03342759 chr3:160939853 NMD3 -0.57 -8.5 -0.42 5.94e-16 Parkinson's disease; LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg11494091 chr17:61959527 GH2 0.45 8.41 0.41 1.09e-15 Prudent dietary pattern; LIHC cis rs2176862 1.000 rs56398705 chr3:46619615 C/G cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.3 -0.32 9.3e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs3741404 0.620 rs882147 chr11:63976689 T/A cg18225595 chr11:63971243 STIP1 0.64 10.54 0.5 1.13e-22 Platelet count; LIHC cis rs7833790 0.724 rs72603871 chr8:82754460 C/G cg17211192 chr8:82754475 SNX16 0.57 10.43 0.49 2.77e-22 Diastolic blood pressure; LIHC cis rs703842 0.928 rs724834 chr12:58180416 G/C cg18357645 chr12:58087776 OS9 -0.45 -6.91 -0.35 2.43e-11 Multiple sclerosis; LIHC cis rs769267 0.930 rs1865034 chr19:19605763 C/T cg03709012 chr19:19516395 GATAD2A 1.0 18.21 0.7 2.91e-52 Tonsillectomy; LIHC cis rs8062405 0.895 rs56186137 chr16:28825953 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.26e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.53 0.38 4.5e-13 Electroencephalogram traits; LIHC cis rs13088318 0.504 rs2553419 chr3:101068620 C/T cg19452782 chr3:101232218 SENP7 -0.42 -6.24 -0.32 1.32e-9 Allergic disease (asthma, hay fever or eczema); LIHC trans rs11148252 0.904 rs3892337 chr13:53029485 C/G cg18335740 chr13:41363409 SLC25A15 0.35 6.06 0.31 3.51e-9 Lewy body disease; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.57 0.56 4.62e-30 Prudent dietary pattern; LIHC cis rs6840360 1.000 rs2007445 chr4:152600370 C/T cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.42e-10 Intelligence (multi-trait analysis); LIHC trans rs2516739 1.000 rs2516739 chr16:2097158 A/G cg13974317 chr22:21056282 TMEM191A -0.52 -6.16 -0.32 1.99e-9 Longevity; LIHC cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.18 0.44 4.13e-18 Bipolar disorder; LIHC cis rs4663866 0.901 rs71426512 chr2:239187128 C/T cg16914508 chr2:239161102 PER2 0.83 5.97 0.31 5.94e-9 Irritable bowel syndrome; LIHC cis rs1865760 0.566 rs2032443 chr6:26046802 A/G cg18357526 chr6:26021779 HIST1H4A 0.48 7.13 0.36 6.01e-12 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24511898 chr2:242576823 ATG4B;THAP4 0.43 7.38 0.37 1.18e-12 Cognitive function; LIHC cis rs10876993 0.893 rs1678504 chr12:58085498 G/C cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.02 -0.31 4.51e-9 Celiac disease or Rheumatoid arthritis; LIHC trans rs4818225 0.536 rs2838000 chr21:42646518 A/G cg00046021 chr7:100858451 PLOD3 -0.54 -6.45 -0.33 3.92e-10 Educational attainment; LIHC cis rs2370759 1.000 rs11594963 chr10:32625736 G/A cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs1448094 0.512 rs57278040 chr12:86237886 A/G cg02569458 chr12:86230093 RASSF9 0.48 6.36 0.33 6.52e-10 Major depressive disorder; LIHC cis rs74181299 0.684 rs1420183 chr2:65309988 A/G cg05010058 chr2:65284262 CEP68 -0.39 -6.3 -0.32 9.17e-10 Pulse pressure; LIHC cis rs7208859 0.615 rs216462 chr17:28895897 T/C cg13385521 chr17:29058706 SUZ12P -0.68 -6.26 -0.32 1.16e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6952808 1.000 rs4721121 chr7:1892565 A/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.46 -0.33 3.61e-10 Bipolar disorder and schizophrenia; LIHC cis rs2274273 0.805 rs60972460 chr14:55571773 A/T cg04306507 chr14:55594613 LGALS3 0.31 5.92 0.3 7.94e-9 Protein biomarker; LIHC cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg07061783 chr6:25882402 NA -0.47 -6.66 -0.34 1.13e-10 Blood metabolite levels; LIHC cis rs1355223 0.902 rs7102625 chr11:34739717 A/C cg11058730 chr11:34937778 PDHX;APIP 0.42 6.04 0.31 4.04e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6942756 0.715 rs6467242 chr7:129001173 T/A cg02491457 chr7:128862824 NA -0.56 -8.52 -0.42 5.21e-16 White matter hyperintensity burden; LIHC cis rs11758351 0.866 rs75091077 chr6:26207546 A/C cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs2717559 0.542 rs11774823 chr8:143887568 G/T cg06565975 chr8:143823917 SLURP1 -0.4 -6.63 -0.34 1.32e-10 Urinary tract infection frequency; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.71 -0.3 2.45e-8 Total body bone mineral density; LIHC cis rs9611565 0.592 rs8779 chr22:42070276 T/C cg06634786 chr22:41940651 POLR3H 0.71 7.33 0.37 1.65e-12 Vitiligo; LIHC trans rs1005277 0.577 rs4934906 chr10:38015028 C/T cg23533926 chr12:111358616 MYL2 -0.32 -6.36 -0.33 6.62e-10 Extrinsic epigenetic age acceleration; LIHC cis rs1986734 0.555 rs12500824 chr4:77416627 A/G cg24201034 chr4:77507246 SHROOM3 -0.37 -5.77 -0.3 1.76e-8 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs986417 0.901 rs1950316 chr14:61018305 T/C cg27398547 chr14:60952738 C14orf39 0.71 7.93 0.39 3.1e-14 Gut microbiota (bacterial taxa); LIHC cis rs589448 0.902 rs315113 chr12:69786543 G/T cg22834771 chr12:69754056 YEATS4 0.51 9.34 0.45 1.28e-18 Cerebrospinal fluid biomarker levels; LIHC cis rs6586163 1.000 rs1926196 chr10:90753748 C/T cg03111039 chr10:90751583 FAS;ACTA2 0.57 8.4 0.41 1.23e-15 Chronic lymphocytic leukemia; LIHC cis rs2066819 1.000 rs79824801 chr12:56728137 T/C cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs2180341 1.000 rs2180341 chr6:127600630 C/T cg27446573 chr6:127587934 RNF146 0.98 14.99 0.63 2.05e-39 Breast cancer; LIHC cis rs7666738 0.830 rs10005173 chr4:98816062 T/C cg05340658 chr4:99064831 C4orf37 0.62 11.24 0.52 3.65e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs57221529 0.655 rs11948381 chr5:568413 A/T cg09021430 chr5:549028 NA -0.43 -8.86 -0.43 4.4e-17 Lung disease severity in cystic fibrosis; LIHC cis rs17106184 1.000 rs60048959 chr1:51403897 C/T cg07174182 chr1:51127561 FAF1 -0.75 -7.9 -0.39 3.96e-14 Type 2 diabetes; LIHC cis rs9486715 1.000 rs9486725 chr6:97061159 C/T cg06623918 chr6:96969491 KIAA0776 -0.85 -13.94 -0.6 2.75e-35 Headache; LIHC cis rs8084351 0.577 rs4315409 chr18:50660629 C/T cg24270629 chr18:50823537 DCC -0.44 -6.47 -0.33 3.3e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9916302 0.904 rs10432031 chr17:37397852 G/A cg07936489 chr17:37558343 FBXL20 -0.8 -12.76 -0.57 9.38e-31 Glomerular filtration rate (creatinine); LIHC cis rs1577917 0.916 rs12203358 chr6:86603224 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.88 -0.35 2.89e-11 Response to antipsychotic treatment; LIHC cis rs7107174 0.892 rs3018313 chr11:77989644 C/T cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs4853012 0.838 rs72915068 chr2:74356185 G/A cg05890377 chr2:74357713 NA 0.64 13.16 0.58 2.71e-32 Gestational age at birth (maternal effect); LIHC cis rs10078 0.559 rs2037077 chr5:447226 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.74 9.58 0.46 2.08e-19 Fat distribution (HIV); LIHC cis rs79149102 0.579 rs73438569 chr15:75354486 T/A cg17294928 chr15:75287854 SCAMP5 -0.5 -6.27 -0.32 1.09e-9 Lung cancer; LIHC cis rs807029 0.577 rs3740489 chr10:102754238 A/G cg27255678 chr10:102756921 LZTS2 0.51 7.17 0.36 4.72e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17848531 chr2:182756352 SSFA2 0.46 6.25 0.32 1.24e-9 Pancreatic cancer; LIHC cis rs858239 0.601 rs10278776 chr7:23169759 C/T cg23682824 chr7:23144976 KLHL7 0.44 6.57 0.33 1.84e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs317689 0.918 rs581911 chr12:69738293 C/T cg14784868 chr12:69753453 YEATS4 0.67 10.14 0.48 2.65e-21 Response to diuretic therapy; LIHC cis rs4975616 0.869 rs452932 chr5:1330253 T/C cg06550200 chr5:1325588 CLPTM1L -0.69 -11.0 -0.51 2.64e-24 Lung cancer; LIHC cis rs1538970 0.924 rs1006216 chr1:45909994 A/G cg24296786 chr1:45957014 TESK2 -0.51 -7.42 -0.37 9.41e-13 Platelet count; LIHC cis rs2070488 1.000 rs3792527 chr3:38493212 T/C cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC cis rs10540 0.730 rs61877766 chr11:512973 T/G cg03352830 chr11:487213 PTDSS2 0.79 6.39 0.33 5.48e-10 Body mass index; LIHC trans rs72960926 0.744 rs56365866 chr6:74910810 T/C cg07247405 chr1:2484626 LOC115110 0.53 6.1 0.31 2.91e-9 Metabolite levels (MHPG); LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.72 -10.78 -0.5 1.55e-23 Lymphocyte counts; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.68 0.8 5.83e-78 Prudent dietary pattern; LIHC cis rs10508774 1.000 rs1829545 chr10:32906377 G/A cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7587476 0.531 rs35933323 chr2:215674090 T/G cg04530015 chr2:215796436 ABCA12 0.45 7.55 0.38 4.06e-13 Neuroblastoma; LIHC cis rs2280018 1.000 rs2280017 chr16:15151361 A/G cg07549590 chr16:15018862 NA 0.34 6.32 0.32 8.32e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6426558 0.559 rs2813947 chr1:227459413 G/T cg10327440 chr1:227177885 CDC42BPA 0.42 6.39 0.33 5.37e-10 Neutrophil percentage of white cells; LIHC cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg19318889 chr4:1322082 MAEA 0.47 6.51 0.33 2.69e-10 Obesity-related traits; LIHC cis rs1552244 0.808 rs7615088 chr3:10035896 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs11645898 0.504 rs79169855 chr16:71950201 A/G cg03805757 chr16:71968109 PKD1L3 -0.84 -7.96 -0.4 2.51e-14 Blood protein levels; LIHC cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg06481639 chr22:41940642 POLR3H -0.69 -7.1 -0.36 7.24e-12 Vitiligo; LIHC cis rs12824058 1.000 rs12824058 chr12:130804334 A/G cg26677194 chr12:130822605 PIWIL1 0.5 6.69 0.34 9.05e-11 Menopause (age at onset); LIHC cis rs11122272 0.735 rs2790893 chr1:231508976 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.75 -0.5 1.99e-23 Hemoglobin concentration; LIHC cis rs7586673 1.000 rs16845584 chr2:161923830 C/T cg22496339 chr2:162101262 NA -0.68 -10.42 -0.49 2.93e-22 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.872 rs2486445 chr1:46605369 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.44 6.64 0.34 1.26e-10 Red blood cell count;Reticulocyte count; LIHC trans rs1005277 0.579 rs2749616 chr10:38510993 A/T cg23533926 chr12:111358616 MYL2 -0.33 -6.26 -0.32 1.12e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2073300 0.609 rs2281434 chr20:23378101 C/A cg12062639 chr20:23401060 NAPB 1.08 14.26 0.61 1.61e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6429082 0.967 rs704709 chr1:235620964 C/T cg26050004 chr1:235667680 B3GALNT2 0.39 6.43 0.33 4.18e-10 Adiposity; LIHC cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg18357526 chr6:26021779 HIST1H4A -0.9 -12.69 -0.57 1.72e-30 Intelligence (multi-trait analysis); LIHC cis rs7187994 0.848 rs34179694 chr16:84776522 A/G cg07082267 chr16:85429035 NA 0.37 6.02 0.31 4.62e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs7937890 0.559 rs6486197 chr11:14529874 C/G cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs7216064 1.000 rs35243555 chr17:65876477 G/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs882732 1.000 rs882732 chr14:95027722 G/A cg14866387 chr14:95027382 SERPINA4 -0.42 -6.06 -0.31 3.56e-9 Blood protein levels; LIHC cis rs9296092 0.538 rs9469491 chr6:33521545 A/G cg13560919 chr6:33536144 NA 0.38 6.47 0.33 3.43e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs4665809 1.000 rs2891490 chr2:26325927 T/C cg04944784 chr2:26401820 FAM59B -0.65 -8.27 -0.41 3.05e-15 Gut microbiome composition (summer); LIHC cis rs1336900 0.637 rs35967040 chr1:150555588 A/C cg17724175 chr1:150552817 MCL1 -0.56 -11.21 -0.52 4.82e-25 Blood protein levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13881405 chr9:92220388 GADD45G 0.41 6.34 0.32 7.33e-10 Pancreatic cancer; LIHC cis rs12478296 1.000 rs59036157 chr2:243040228 C/A cg06360820 chr2:242988706 NA -0.94 -12.35 -0.56 3.3e-29 Obesity-related traits; LIHC cis rs6459788 0.934 rs10807646 chr7:157260294 C/T cg06271696 chr7:157225062 NA -0.37 -6.4 -0.33 5.11e-10 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs6912958 0.535 rs448580 chr6:88040399 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.6 11.11 0.52 1.05e-24 Monocyte percentage of white cells; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg11877270 chr2:65658583 SPRED2 -0.4 -6.14 -0.32 2.28e-9 Body mass index; LIHC trans rs7246657 0.943 rs10424574 chr19:37838393 A/G cg10208301 chr11:6592745 DNHD1 0.47 6.35 0.32 6.86e-10 Coronary artery calcification; LIHC cis rs7075426 0.669 rs10887608 chr10:88191938 A/G cg07322936 chr10:88137208 NA -0.47 -6.09 -0.31 3.1e-9 Migraine without aura; LIHC trans rs3783890 0.887 rs71429791 chr14:93798425 G/A cg02802420 chr16:69363236 PDF;COG8 0.33 6.44 0.33 4e-10 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12828867 chr5:61708427 IPO11 0.46 6.21 0.32 1.57e-9 Pancreatic cancer; LIHC cis rs769267 0.930 rs2301786 chr19:19413947 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.1 0.31 2.93e-9 Tonsillectomy; LIHC cis rs7914558 0.966 rs11191438 chr10:104637864 C/G cg15744005 chr10:104629667 AS3MT -0.39 -8.84 -0.43 5.06e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4474465 0.688 rs4944210 chr11:78282878 C/T cg27205649 chr11:78285834 NARS2 0.5 7.82 0.39 6.79e-14 Alzheimer's disease (survival time); LIHC cis rs2455799 0.613 rs1969095 chr3:15733552 C/T cg12698662 chr3:15914712 MIR563 -0.37 -6.75 -0.34 6.25e-11 Mean platelet volume; LIHC cis rs17094222 0.812 rs4919479 chr10:102434147 A/G cg26540559 chr10:102447443 NA 0.33 6.28 0.32 1.02e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1113500 0.805 rs11185248 chr1:108611001 A/G cg06207961 chr1:108661230 NA -0.31 -5.77 -0.3 1.82e-8 Growth-regulated protein alpha levels; LIHC trans rs10411161 0.702 rs10402630 chr19:52384570 G/A cg22319618 chr22:45562946 NUP50 -0.59 -8.12 -0.4 8.66e-15 Breast cancer; LIHC cis rs4689388 0.929 rs1046320 chr4:6304344 C/T cg25554036 chr4:6271136 WFS1 0.41 6.17 0.32 1.98e-9 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs7119038 0.818 rs76704408 chr11:118683327 G/T cg19308663 chr11:118741387 NA 0.39 6.04 0.31 4.11e-9 Sjögren's syndrome; LIHC cis rs7959452 0.535 rs11615712 chr12:69619736 A/T cg20891283 chr12:69753455 YEATS4 -0.68 -12.37 -0.56 2.57e-29 Blood protein levels; LIHC cis rs3020736 0.500 rs5996111 chr22:42493902 C/T cg15557168 chr22:42548783 NA 0.46 7.08 0.36 8.47e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs2072499 1.000 rs2253809 chr1:156172125 T/C cg25208724 chr1:156163844 SLC25A44 0.91 15.28 0.64 1.49e-40 Testicular germ cell tumor; LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg09417038 chr21:47716443 C21orf57 0.48 7.23 0.36 3.21e-12 Testicular germ cell tumor; LIHC cis rs8062405 0.755 rs2077031 chr16:28603168 T/A cg00204512 chr16:28754710 NA 0.4 6.92 0.35 2.26e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg06873352 chr17:61820015 STRADA 0.57 8.71 0.43 1.35e-16 Height; LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg02249930 chr10:70166207 RUFY2 -0.58 -6.44 -0.33 4.15e-10 Bronchial neuroendocrine tumor; LIHC trans rs1005277 0.522 rs7090858 chr10:38003670 A/C cg27523141 chr10:43048294 ZNF37B -0.39 -7.0 -0.35 1.35e-11 Extrinsic epigenetic age acceleration; LIHC cis rs74233809 0.748 rs10786736 chr10:104849116 G/C cg03493300 chr10:104813866 CNNM2 0.45 5.99 0.31 5.2e-9 Birth weight; LIHC cis rs912057 0.526 rs746453 chr6:6734221 C/A cg06612196 chr6:6737390 NA 0.5 9.09 0.44 7.92e-18 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs9868809 0.881 rs2286652 chr3:48689192 G/A cg07636037 chr3:49044803 WDR6 -0.64 -7.21 -0.36 3.6e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs2072499 0.931 rs1052053 chr1:156202173 A/G cg24450063 chr1:156163899 SLC25A44 0.74 13.0 0.58 1.08e-31 Testicular germ cell tumor; LIHC cis rs4423214 0.592 rs7114252 chr11:71237606 G/A cg05163923 chr11:71159392 DHCR7 -0.59 -7.23 -0.36 3.27e-12 Vitamin D levels; LIHC cis rs4665809 0.878 rs35709953 chr2:26334997 G/A cg26119090 chr2:26468346 HADHA;HADHB 0.74 8.13 0.4 7.98e-15 Gut microbiome composition (summer); LIHC cis rs16854884 0.683 rs6766544 chr3:143736659 G/T cg06585982 chr3:143692056 C3orf58 0.55 7.17 0.36 4.79e-12 Economic and political preferences (feminism/equality); LIHC cis rs4925386 1.000 rs4925382 chr20:60918542 G/C cg24112000 chr20:60950667 NA 0.45 7.05 0.36 9.99e-12 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs875971 0.862 rs10256544 chr7:65675128 A/G cg11764359 chr7:65958608 NA 0.81 13.54 0.59 9.55e-34 Aortic root size; LIHC cis rs34540877 1.000 rs34767952 chr19:33122517 G/A cg22980127 chr19:33182716 NUDT19 1.03 6.83 0.35 3.95e-11 Red cell distribution width; LIHC cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg23978390 chr7:1156363 C7orf50 0.54 7.93 0.39 3.14e-14 Longevity;Endometriosis; LIHC cis rs12995491 0.933 rs34029976 chr2:88537797 T/C cg14558114 chr2:88469736 THNSL2 -0.37 -5.8 -0.3 1.49e-8 Response to metformin (IC50); LIHC cis rs3782089 1.000 rs11600543 chr11:65298939 G/A cg21890820 chr11:65308645 LTBP3 0.93 6.55 0.33 2.08e-10 Height; LIHC trans rs3960554 0.808 rs868555 chr7:75697418 G/A cg19862616 chr7:65841803 NCRNA00174 0.6 8.39 0.41 1.3e-15 Eotaxin levels; LIHC cis rs2425143 1.000 rs2425093 chr20:34306875 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Blood protein levels; LIHC cis rs7772486 0.738 rs2246334 chr6:146183635 G/A cg05347473 chr6:146136440 FBXO30 0.38 6.13 0.31 2.42e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs929354 1.000 rs1182378 chr7:157048322 T/C cg17757837 chr7:157058334 UBE3C -0.8 -14.12 -0.61 5.69e-36 Body mass index; LIHC cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg11644478 chr21:40555479 PSMG1 0.83 10.69 0.5 3.38e-23 Cognitive function; LIHC cis rs7208859 0.623 rs7214570 chr17:29147164 A/G cg14067834 chr17:29058358 SUZ12P 0.64 6.53 0.33 2.37e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7772486 0.686 rs9497395 chr6:146013592 A/G cg13319975 chr6:146136371 FBXO30 0.37 6.01 0.31 4.88e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2033711 0.837 rs3764535 chr19:58929052 G/A cg26874164 chr19:58962979 ZNF324B 0.44 6.05 0.31 3.86e-9 Uric acid clearance; LIHC cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.63 0.56 2.89e-30 Alzheimer's disease; LIHC trans rs9914544 0.564 rs11548434 chr17:18761508 G/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.59 -0.34 1.69e-10 Educational attainment (years of education); LIHC cis rs6951245 1.000 rs11763020 chr7:1060288 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -6.06 -0.31 3.53e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11098499 0.954 rs3890049 chr4:120326283 T/A cg09307838 chr4:120376055 NA 0.77 12.14 0.55 1.93e-28 Corneal astigmatism; LIHC cis rs67311347 0.911 rs6775936 chr3:40377399 T/G cg00656387 chr3:40428638 ENTPD3 0.41 6.72 0.34 7.68e-11 Renal cell carcinoma; LIHC cis rs17685 0.884 rs6978677 chr7:75636240 C/T cg04592579 chr7:75616294 TMEM120A 0.36 6.17 0.32 1.89e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs780096 0.526 rs11682621 chr2:27749669 G/A cg27432699 chr2:27873401 GPN1 -0.6 -8.67 -0.42 1.72e-16 Total body bone mineral density; LIHC cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg18357526 chr6:26021779 HIST1H4A -0.49 -6.68 -0.34 9.94e-11 Blood metabolite levels; LIHC trans rs1728785 1.000 rs1645938 chr16:68595197 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.5 0.33 2.82e-10 Ulcerative colitis; LIHC cis rs9902453 0.967 rs9900911 chr17:28330280 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs7224737 1.000 rs9889618 chr17:40293467 C/T cg20291162 chr17:40259547 DHX58 -0.4 -6.38 -0.33 5.82e-10 Fibrinogen levels; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg12648201 chr2:27665141 KRTCAP3 -0.42 -5.82 -0.3 1.34e-8 Total body bone mineral density; LIHC cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg18357526 chr6:26021779 HIST1H4A 0.62 8.69 0.43 1.58e-16 Blood metabolite levels; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC trans rs2522056 0.808 rs1016988 chr5:131744574 T/C cg13226919 chr1:222919977 FAM177B 0.26 6.29 0.32 9.98e-10 Lymphocyte counts;Fibrinogen; LIHC cis rs2120019 0.505 rs77456790 chr15:75330095 G/T cg15902774 chr15:75289873 SCAMP5 0.46 6.48 0.33 3.27e-10 Blood trace element (Zn levels); LIHC cis rs6748734 1.000 rs6724662 chr2:241831560 A/G cg04034577 chr2:241836375 C2orf54 -0.41 -8.12 -0.4 8.53e-15 Urinary metabolites; LIHC cis rs597539 0.652 rs613128 chr11:68638058 G/T cg04772025 chr11:68637568 NA 0.46 6.22 0.32 1.44e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs875971 0.545 rs4718364 chr7:66001340 C/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 7.0 0.35 1.34e-11 Aortic root size; LIHC cis rs7220401 0.789 rs3760456 chr17:27948844 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -12.25 -0.55 7.7e-29 Coronary artery disease; LIHC cis rs10193935 0.901 rs9309082 chr2:42581412 A/G cg27598129 chr2:42591480 NA -0.77 -11.79 -0.54 3.68e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs10078 0.571 rs2721014 chr5:463539 G/A cg07599136 chr5:415885 AHRR 0.77 12.57 0.56 4.66e-30 Fat distribution (HIV); LIHC cis rs6545883 0.929 rs3821222 chr2:61713526 C/G cg15711740 chr2:61764176 XPO1 -0.41 -5.8 -0.3 1.5e-8 Tuberculosis; LIHC cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg08645402 chr16:4508243 NA -0.36 -6.86 -0.35 3.25e-11 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00359868 chr21:40752339 WRB 0.47 6.36 0.33 6.38e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17539620 0.624 rs62432739 chr6:154835926 A/G cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs4718428 0.576 rs12698546 chr7:66266906 G/T cg18252515 chr7:66147081 NA -0.64 -8.46 -0.42 7.89e-16 Corneal structure; LIHC cis rs74664507 0.527 rs4961501 chr9:16851678 T/G cg13173848 chr9:16870893 BNC2 0.6 6.55 0.33 2.15e-10 Squamous cell carcinoma; LIHC cis rs797680 0.822 rs7541304 chr1:93757838 T/A cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.87 0.3 1.02e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs11958404 0.932 rs72816540 chr5:157414500 T/C cg05962755 chr5:157440814 NA 0.86 10.11 0.48 3.51e-21 IgG glycosylation; LIHC cis rs10242455 0.571 rs45527841 chr7:99310965 C/T cg18809830 chr7:99032528 PTCD1 -0.85 -6.79 -0.34 4.88e-11 Blood metabolite levels; LIHC trans rs2727020 0.757 rs7924526 chr11:49267043 G/A cg03929089 chr4:120376271 NA 0.67 10.0 0.48 8.13e-21 Coronary artery disease; LIHC cis rs735860 0.700 rs209524 chr6:53213226 G/C cg10236188 chr6:53219634 NA 0.42 7.67 0.38 1.81e-13 Glaucoma; LIHC cis rs2153535 0.580 rs2184586 chr6:8474182 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.01e-16 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25080152 chr8:128748155 MYC 0.45 6.25 0.32 1.23e-9 Lung function (FEV1/FVC); LIHC cis rs1552244 0.882 rs55962400 chr3:10044457 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.58 -8.12 -0.4 8.27e-15 Alzheimer's disease; LIHC cis rs1559088 0.842 rs12977993 chr19:33580453 T/A cg17764715 chr19:33622953 WDR88 0.46 6.83 0.35 3.89e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9467773 1.000 rs6930120 chr6:26555484 A/G cg09904177 chr6:26538194 HMGN4 0.65 13.83 0.6 7.52e-35 Intelligence (multi-trait analysis); LIHC cis rs1997103 1.000 rs6977292 chr7:55396335 T/C cg17469321 chr7:55412551 NA 0.48 7.06 0.36 9.58e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs8017423 0.967 rs4904663 chr14:90729565 G/T cg04374321 chr14:90722782 PSMC1 0.78 15.26 0.64 1.75e-40 Mortality in heart failure; LIHC cis rs12478296 0.901 rs56318767 chr2:243046591 T/A cg18898632 chr2:242989856 NA -0.57 -7.72 -0.39 1.32e-13 Obesity-related traits; LIHC trans rs3749237 0.964 rs10865959 chr3:49891002 G/C cg21659725 chr3:3221576 CRBN 0.78 12.16 0.55 1.61e-28 Resting heart rate; LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg00656387 chr3:40428638 ENTPD3 0.49 8.35 0.41 1.73e-15 Renal cell carcinoma; LIHC cis rs11676348 0.772 rs12471105 chr2:218950209 G/A cg00012203 chr2:219082015 ARPC2 -0.45 -6.06 -0.31 3.55e-9 Ulcerative colitis; LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg07234388 chr1:156261841 TMEM79 0.52 9.39 0.45 8.5e-19 Tonsillectomy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05835761 chr10:73648991 NA 0.52 7.8 0.39 7.53e-14 Pancreatic cancer; LIHC cis rs933688 0.877 rs1477349 chr5:90707773 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.61 0.67 7.88e-46 Smoking behavior; LIHC cis rs2070433 0.904 rs11701571 chr21:47963149 A/G cg12379764 chr21:47803548 PCNT 0.6 8.4 0.41 1.23e-15 Lymphocyte counts; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg24846343 chr22:24311635 DDTL 0.6 10.91 0.51 5.64e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs644799 1.000 rs518919 chr11:95623313 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.63 8.72 0.43 1.21e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs8180040 0.764 rs13061071 chr3:47138708 G/A cg27129171 chr3:47204927 SETD2 0.67 11.84 0.54 2.54e-27 Colorectal cancer; LIHC cis rs10744422 1.000 rs1587856 chr12:123342229 A/G cg18912006 chr12:123335444 HIP1R -0.64 -7.69 -0.38 1.55e-13 Schizophrenia; LIHC trans rs2243480 1.000 rs1701750 chr7:65467145 T/C cg10756647 chr7:56101905 PSPH 1.11 13.6 0.59 5.63e-34 Diabetic kidney disease; LIHC cis rs916888 0.821 rs199507 chr17:44858855 A/G cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs66887589 0.967 rs6844263 chr4:120433807 A/G cg09307838 chr4:120376055 NA 0.5 7.62 0.38 2.58e-13 Diastolic blood pressure; LIHC cis rs6977660 1.000 rs10275322 chr7:19821220 C/T cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC trans rs1814175 0.867 rs7926002 chr11:49616018 A/G cg15704280 chr7:45808275 SEPT13 -0.99 -21.1 -0.75 6.87e-64 Height; LIHC cis rs4665809 1.000 rs6546744 chr2:26302161 A/G cg04944784 chr2:26401820 FAM59B -0.65 -8.29 -0.41 2.58e-15 Gut microbiome composition (summer); LIHC cis rs9611519 0.780 rs1983631 chr22:41644074 C/T cg06634786 chr22:41940651 POLR3H -0.54 -6.45 -0.33 3.72e-10 Neuroticism; LIHC cis rs769267 1.000 rs2301669 chr19:19453560 C/A cg03709012 chr19:19516395 GATAD2A -0.92 -16.02 -0.65 1.72e-43 Tonsillectomy; LIHC cis rs4242434 0.927 rs10095121 chr8:22538426 A/G cg03733263 chr8:22462867 KIAA1967 0.78 12.59 0.56 4.07e-30 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs763121 0.853 rs2281020 chr22:39064406 A/G cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs79387448 0.614 rs985523 chr2:102954376 G/A cg09003973 chr2:102972529 NA 1.11 10.24 0.48 1.26e-21 Gut microbiota (bacterial taxa); LIHC cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11166927 0.703 rs2126128 chr8:140788299 A/G cg16909799 chr8:140841666 TRAPPC9 -0.36 -5.94 -0.31 7.11e-9 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs6831352 0.918 rs35784540 chr4:100061692 T/A cg12011299 chr4:100065546 ADH4 -0.62 -10.39 -0.49 3.69e-22 Alcohol dependence; LIHC cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.37 0.41 1.55e-15 Platelet count; LIHC trans rs17464492 0.592 rs2121631 chr8:128386556 A/G cg09205595 chr7:150782539 AGAP3 -0.38 -6.31 -0.32 8.53e-10 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs2997447 0.706 rs17184898 chr1:26447870 A/T cg19633962 chr1:26362018 EXTL1 -0.64 -5.88 -0.3 9.64e-9 QRS complex (12-leadsum); LIHC trans rs1814175 0.527 rs3974435 chr11:49619533 G/A cg18944383 chr4:111397179 ENPEP 0.34 7.75 0.39 1.03e-13 Height; LIHC cis rs9814567 1.000 rs2887797 chr3:134202506 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.36 -0.56 3.02e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs56011263 0.687 rs4690292 chr4:703712 A/G cg20735989 chr4:730612 PCGF3 -0.67 -8.67 -0.42 1.74e-16 White blood cell count; LIHC cis rs734999 0.545 rs28690427 chr1:2571823 A/G cg18854424 chr1:2615690 NA -0.32 -7.14 -0.36 5.66e-12 Ulcerative colitis; LIHC cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs11229555 0.645 rs12274866 chr11:58177129 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2834188 1.000 rs1018741 chr21:34686345 G/A cg14352951 chr21:34696688 IFNAR1 0.47 6.43 0.33 4.24e-10 Narcolepsy; LIHC cis rs2404602 1.000 rs12594541 chr15:76834368 G/A cg03037974 chr15:76606532 NA 0.72 13.82 0.6 8.32e-35 Blood metabolite levels; LIHC cis rs875971 0.862 rs880166 chr7:65670762 T/C cg18252515 chr7:66147081 NA 0.42 5.83 0.3 1.31e-8 Aortic root size; LIHC cis rs208520 1.000 rs12191598 chr6:66983962 T/C cg07460842 chr6:66804631 NA 0.67 7.3 0.37 2e-12 Exhaled nitric oxide output; LIHC cis rs722599 0.748 rs17102884 chr14:75374899 C/T cg08847533 chr14:75593920 NEK9 -0.54 -8.91 -0.43 2.98e-17 IgG glycosylation; LIHC cis rs1506636 0.708 rs7788702 chr7:123237421 C/T cg03229431 chr7:123269106 ASB15 0.48 9.69 0.46 8.91e-20 Plateletcrit;Platelet count; LIHC cis rs140364877 1 rs140364877 chr7:1885178 C/T cg21782813 chr7:2030301 MAD1L1 0.42 7.11 0.36 6.94e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs4988958 0.565 rs885088 chr2:103039044 A/G cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma (childhood onset); LIHC cis rs9814567 1.000 rs17694011 chr3:134213981 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.13 -0.55 2.01e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7903847 0.642 rs1048442 chr10:99160152 A/G cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.45e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs17854409 0.764 rs8114722 chr20:61478492 G/A cg07645718 chr20:61493192 TCFL5 0.8 6.18 0.32 1.83e-9 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03909902 chr12:108154529 PRDM4 0.52 6.53 0.33 2.43e-10 Lung function (FEV1/FVC); LIHC cis rs2115630 0.645 rs6496284 chr15:85178270 A/G cg12501888 chr15:85177176 SCAND2 -0.47 -7.08 -0.36 8.16e-12 P wave terminal force; LIHC cis rs4820539 0.932 rs3788349 chr22:23467950 A/G cg14186256 chr22:23484241 RTDR1 0.98 21.26 0.75 1.65e-64 Bone mineral density; LIHC cis rs7100689 0.646 rs1340382 chr10:82096997 G/C cg00277334 chr10:82204260 NA -0.56 -7.08 -0.36 8.39e-12 Post bronchodilator FEV1; LIHC cis rs3857067 0.806 rs6532472 chr4:95110113 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs8072100 0.875 rs12451409 chr17:45544856 A/G cg08085267 chr17:45401833 C17orf57 -0.42 -6.17 -0.32 1.91e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6754311 0.550 rs12994270 chr2:136518103 T/A cg17750252 chr2:136567154 LCT 0.35 6.09 0.31 3.09e-9 Mosquito bite size; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01177235 chr9:33265011 SUGT1P1;CHMP5;BAG1 -0.49 -6.51 -0.33 2.72e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs910316 0.763 rs12588981 chr14:75460561 A/G cg08847533 chr14:75593920 NEK9 0.88 18.17 0.7 4.21e-52 Height; LIHC cis rs9309711 0.961 rs11675119 chr2:3476422 C/A cg04359351 chr2:3481828 TTC15 0.3 5.76 0.3 1.88e-8 Neurofibrillary tangles; LIHC cis rs4925386 0.559 rs2427291 chr20:60921324 G/A cg06026331 chr20:60912101 LAMA5 0.66 9.3 0.45 1.77e-18 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs1003719 0.742 rs8129231 chr21:38501034 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.23 -0.52 4.09e-25 Eye color traits; LIHC cis rs17094222 0.812 rs1891915 chr10:102433860 T/C cg26540559 chr10:102447443 NA 0.33 6.37 0.33 6.18e-10 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg16262614 chr3:133464971 TF -0.28 -6.2 -0.32 1.6e-9 Iron status biomarkers; LIHC trans rs17433710 0.516 rs6689396 chr1:162676698 C/T cg14646974 chr10:38645378 HSD17B7P2 -0.45 -6.31 -0.32 8.52e-10 Dupuytren's disease; LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg03721293 chr16:90014378 DEF8 0.43 7.2 0.36 3.97e-12 Skin colour saturation; LIHC cis rs600231 0.706 rs3782091 chr11:65336483 G/T cg10628098 chr11:65292300 SCYL1 -0.38 -5.94 -0.31 6.94e-9 Bone mineral density; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg11905131 chr22:24372483 LOC391322 -0.71 -10.91 -0.51 5.44e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11628318 0.515 rs1951630 chr14:103076807 A/T cg12046867 chr14:103022105 NA -0.38 -5.73 -0.3 2.16e-8 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01947862 chr2:86116624 ST3GAL5 0.49 6.66 0.34 1.12e-10 Pancreatic cancer; LIHC cis rs7772486 0.558 rs9376965 chr6:146130055 G/A cg05347473 chr6:146136440 FBXO30 0.47 6.98 0.35 1.52e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7089973 0.668 rs7077148 chr10:116644896 A/G cg23260525 chr10:116636907 FAM160B1 0.37 7.24 0.36 2.98e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs13108904 0.557 rs1250095 chr4:1239312 C/T cg19318889 chr4:1322082 MAEA -0.62 -9.98 -0.47 9.33e-21 Obesity-related traits; LIHC cis rs655641 0.954 rs497711 chr11:85764875 T/G cg09030501 chr11:85779252 PICALM -0.51 -6.16 -0.32 2.03e-9 Platelet count; LIHC cis rs74417235 0.639 rs2396994 chr5:154052750 A/T cg08893839 chr5:154027129 NA -0.51 -6.92 -0.35 2.19e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs9921222 0.521 rs757460 chr16:367174 G/C cg26944245 chr16:421049 TMEM8A;MRPL28 0.41 6.68 0.34 9.52e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs58688157 0.883 rs7936397 chr11:577534 G/A cg16486109 chr11:613632 IRF7 0.59 6.24 0.32 1.29e-9 Systemic lupus erythematosus; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.49 -0.38 5.88e-13 Lymphocyte counts; LIHC cis rs7116495 0.609 rs595062 chr11:71809635 C/T cg26138937 chr11:71823887 C11orf51 1.34 10.79 0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC cis rs4742903 0.967 rs10991120 chr9:106909051 C/T cg14250997 chr9:106856677 SMC2 0.38 6.75 0.34 6.24e-11 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs11014306 1.000 rs4504964 chr10:25208507 G/A cg19056833 chr13:114749079 RASA3 0.65 6.19 0.32 1.69e-9 Metabolite levels (Pyroglutamine); LIHC cis rs3806843 0.766 rs6848 chr5:140086062 A/T cg19875535 chr5:140030758 IK -0.4 -6.46 -0.33 3.71e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs10911363 0.659 rs7518244 chr1:183434807 C/T cg09173681 chr1:183549694 NCF2 -0.54 -9.51 -0.46 3.57e-19 Systemic lupus erythematosus; LIHC cis rs12701220 0.655 rs10215292 chr7:1135263 A/G cg16145915 chr7:1198662 ZFAND2A -0.34 -6.79 -0.34 4.94e-11 Bronchopulmonary dysplasia; LIHC cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg17372223 chr3:52568218 NT5DC2 0.36 5.84 0.3 1.2e-8 Cognitive function; LIHC cis rs7780883 0.821 rs1978181 chr7:77061342 A/G cg12876866 chr7:77025528 PION -0.48 -5.83 -0.3 1.29e-8 Cervical cancer; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg07677032 chr17:61819896 STRADA 0.41 5.84 0.3 1.19e-8 Prudent dietary pattern; LIHC cis rs796364 0.806 rs79156935 chr2:200913822 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs10779751 0.734 rs2791648 chr1:11132638 G/T cg08854313 chr1:11322531 MTOR 0.66 10.04 0.48 6.06e-21 Body mass index; LIHC cis rs1348850 0.632 rs11678875 chr2:178509068 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.81 0.39 7.22e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs28735056 0.587 rs8093548 chr18:77636451 G/A cg20368463 chr18:77673604 PQLC1 -0.49 -8.31 -0.41 2.32e-15 Schizophrenia; LIHC cis rs9640161 0.750 rs11765644 chr7:150026339 C/G cg27494647 chr7:150038898 RARRES2 0.31 5.71 0.3 2.44e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg24846343 chr22:24311635 DDTL -0.66 -12.77 -0.57 8.28e-31 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7716219 0.572 rs62359607 chr5:54877085 T/C cg14753740 chr5:54468940 CDC20B;MIR449C 0.43 6.11 0.31 2.73e-9 Height; LIHC trans rs1814175 0.619 rs847644 chr11:49918418 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs2832077 0.527 rs1048546 chr21:30244877 G/T cg03476357 chr21:30257390 N6AMT1 -0.53 -7.8 -0.39 7.35e-14 Cognitive test performance; LIHC cis rs8180040 0.900 rs4858894 chr3:47484953 C/G cg16586182 chr3:47516702 SCAP -0.58 -11.36 -0.52 1.41e-25 Colorectal cancer; LIHC trans rs66573146 0.831 rs56300156 chr4:6990813 G/C cg07817883 chr1:32538562 TMEM39B 1.17 9.23 0.45 2.83e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs8053891 0.507 rs34150651 chr16:72028112 G/A cg01557791 chr16:72042693 DHODH -0.39 -6.17 -0.32 1.91e-9 Coronary artery disease; LIHC cis rs6089829 0.962 rs4809462 chr20:61661560 A/G cg03213289 chr20:61660250 NA 0.49 8.8 0.43 7.1e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs4722166 0.597 rs1554606 chr7:22768707 T/G cg05472934 chr7:22766657 IL6 0.48 7.76 0.39 9.76e-14 Lung cancer; LIHC cis rs7582720 1.000 rs72932789 chr2:203699379 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs847851 0.617 rs9368844 chr6:34978030 T/C cg13137465 chr6:34857473 ANKS1A 0.67 7.59 0.38 2.97e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs2479724 0.776 rs12523672 chr6:41749692 T/G cg17623882 chr6:41773611 USP49 0.56 8.72 0.43 1.23e-16 Menarche (age at onset); LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg13409248 chr3:40428643 ENTPD3 -0.5 -8.49 -0.42 6.42e-16 Renal cell carcinoma; LIHC cis rs950169 1.000 rs12902672 chr15:84716986 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs644799 0.710 rs11021311 chr11:95505227 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.8 12.32 0.55 3.98e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs743757 1.000 rs6446206 chr3:50455470 G/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.49 7.6 0.38 2.92e-13 Diastolic blood pressure; LIHC trans rs2727020 0.553 rs3907576 chr11:49536639 A/C cg15704280 chr7:45808275 SEPT13 -0.98 -19.97 -0.73 2.33e-59 Coronary artery disease; LIHC cis rs2806561 0.704 rs2746560 chr1:23526279 G/A cg19743168 chr1:23544995 NA 0.38 6.28 0.32 1.05e-9 Height; LIHC cis rs10088262 0.629 rs12541177 chr8:124800273 G/T cg02993010 chr8:124780839 FAM91A1 -0.47 -6.03 -0.31 4.32e-9 Pancreatic cancer; LIHC cis rs10791097 0.694 rs12361892 chr11:130744490 T/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11583043 0.874 rs41312668 chr1:101443582 C/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.12 0.31 2.57e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9399135 1.000 rs9399135 chr6:135368314 G/A cg22676075 chr6:135203613 NA 0.39 6.18 0.32 1.78e-9 Red blood cell count; LIHC cis rs10206020 0.921 rs4072986 chr2:1547734 C/G cg01028140 chr2:1542097 TPO -0.45 -7.16 -0.36 4.98e-12 IgG glycosylation; LIHC cis rs782590 0.837 rs782573 chr2:55912961 T/C cg18811423 chr2:55921094 PNPT1 0.93 14.87 0.63 6.14e-39 Metabolic syndrome; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09060823 chr12:56862504 SPRYD4 0.45 6.7 0.34 8.8e-11 Cognitive function; LIHC cis rs11786130 1.000 rs10956401 chr8:129002419 G/A cg01765152 chr8:129005526 PVT1 -0.32 -7.02 -0.35 1.19e-11 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs208346 1.000 rs208346 chr7:2799686 G/T cg19717773 chr7:2847554 GNA12 0.39 7.57 0.38 3.49e-13 Loneliness (linear analysis); LIHC cis rs6088590 0.930 rs6087618 chr20:33288407 C/T cg24642439 chr20:33292090 TP53INP2 0.81 11.61 0.53 1.75e-26 Coronary artery disease; LIHC cis rs597539 0.690 rs647661 chr11:68625875 T/C cg06028808 chr11:68637592 NA 0.44 5.77 0.3 1.82e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2153535 0.580 rs965706 chr6:8464708 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.65 0.38 2e-13 Bipolar disorder; LIHC cis rs9914988 0.778 rs4794837 chr17:27110024 T/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg10862848 chr6:42927986 GNMT -0.3 -6.77 -0.34 5.75e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs79387448 0.745 rs72993760 chr2:103151704 G/A cg09003973 chr2:102972529 NA 0.85 7.47 0.37 6.82e-13 Gut microbiota (bacterial taxa); LIHC cis rs10847980 0.590 rs58182048 chr12:123287708 C/T cg25930673 chr12:123319894 HIP1R 1.09 11.71 0.53 7.59e-27 Adiponectin levels; LIHC cis rs10744422 1.000 rs2135014 chr12:123333065 C/T cg25930673 chr12:123319894 HIP1R -0.93 -12.35 -0.56 3.04e-29 Schizophrenia; LIHC cis rs11122272 0.735 rs2739515 chr1:231514681 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs992157 0.764 rs13020391 chr2:219184436 C/T cg00012203 chr2:219082015 ARPC2 -0.75 -10.45 -0.49 2.23e-22 Colorectal cancer; LIHC cis rs6430585 0.583 rs4988201 chr2:136618507 A/G cg15123519 chr2:136567270 LCT -0.37 -5.92 -0.3 7.82e-9 Corneal structure; LIHC cis rs4953318 0.619 rs13406773 chr2:46362868 T/C cg12428440 chr2:46370979 PRKCE 0.46 6.33 0.32 7.73e-10 Red blood cell count;Hematocrit;Red blood cell traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02250992 chr12:125348168 SCARB1 -0.55 -6.16 -0.32 2.1e-9 Systolic blood pressure; LIHC cis rs2016586 0.929 rs5750161 chr22:36113236 T/C cg26342177 chr22:36113512 APOL5 -0.38 -6.3 -0.32 9.32e-10 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09766628 chr17:4634728 MED11 0.46 6.54 0.33 2.2e-10 Lung function (FEV1/FVC); LIHC cis rs425277 0.539 rs3107142 chr1:2044542 T/C cg04315214 chr1:2043799 PRKCZ 0.46 7.19 0.36 4.04e-12 Height; LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg12016809 chr21:47604291 C21orf56 -0.47 -7.23 -0.36 3.19e-12 Testicular germ cell tumor; LIHC cis rs2901460 0.509 rs12463815 chr2:62087165 C/T cg02183531 chr2:62113199 CCT4 -0.4 -5.88 -0.3 1e-8 Mean corpuscular volume; LIHC cis rs1797081 0.967 rs780633 chr10:16863161 C/T cg23933602 chr10:16859644 RSU1 1.05 23.55 0.79 1.5e-73 Platelet distribution width; LIHC cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.46e-8 Menopause (age at onset); LIHC cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg18252515 chr7:66147081 NA -1.26 -17.06 -0.68 1.18e-47 Diabetic kidney disease; LIHC cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg21664854 chr7:1097933 C7orf50;GPR146 0.74 5.97 0.31 6.1e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs801193 1.000 rs4717310 chr7:66161007 C/T cg11764359 chr7:65958608 NA 0.71 10.72 0.5 2.51e-23 Aortic root size; LIHC cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg13395646 chr4:1353034 KIAA1530 -0.42 -6.27 -0.32 1.11e-9 Longevity; LIHC trans rs877282 0.945 rs12782447 chr10:771870 C/T cg22713356 chr15:30763199 NA 1.37 12.26 0.55 6.87e-29 Uric acid levels; LIHC cis rs4819052 0.851 rs1056100 chr21:46678711 A/C cg22633049 chr21:46681294 NA -0.36 -6.35 -0.32 7.05e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2279817 0.863 rs35871295 chr1:17984468 A/T cg21791023 chr1:18019539 ARHGEF10L -0.65 -7.14 -0.36 5.63e-12 Neuroticism; LIHC cis rs36051895 0.559 rs7874495 chr9:5209804 A/G cg02405213 chr9:5042618 JAK2 -0.61 -10.38 -0.49 3.95e-22 Pediatric autoimmune diseases; LIHC cis rs4319547 0.614 rs10846764 chr12:122874297 T/C cg23029597 chr12:123009494 RSRC2 0.51 7.28 0.37 2.3e-12 Body mass index; LIHC cis rs6062509 0.931 rs4809329 chr20:62348460 C/T cg03999872 chr20:62272968 STMN3 0.41 6.08 0.31 3.29e-9 Prostate cancer; LIHC cis rs8067354 0.645 rs2173119 chr17:57859705 C/T cg13753209 chr17:57696993 CLTC 0.76 12.01 0.54 5.85e-28 Hemoglobin concentration; LIHC trans rs208520 0.789 rs9351549 chr6:66871851 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.61 -0.42 2.75e-16 Exhaled nitric oxide output; LIHC cis rs4819052 0.851 rs28616694 chr21:46674786 G/C cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.39e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg11502198 chr6:26597334 ABT1 0.64 10.12 0.48 3.23e-21 Intelligence (multi-trait analysis); LIHC cis rs864537 0.618 rs2995089 chr1:167431193 G/A cg22356347 chr1:167427500 CD247 -0.39 -6.5 -0.33 2.85e-10 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs6977660 1.000 rs13237667 chr7:19820288 G/C cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg07157834 chr1:205819609 PM20D1 0.77 11.41 0.53 8.73e-26 Menarche (age at onset); LIHC cis rs7945705 0.747 rs11042150 chr11:9010819 T/C cg12365402 chr11:9010492 NRIP3 -0.3 -8.05 -0.4 1.35e-14 Hemoglobin concentration; LIHC cis rs2153535 0.580 rs7341381 chr6:8470537 A/G cg07606381 chr6:8435919 SLC35B3 0.8 12.07 0.55 3.41e-28 Motion sickness; LIHC cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 7.35 0.37 1.47e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.71 11.88 0.54 1.7e-27 Height; LIHC cis rs4819052 0.851 rs28501512 chr21:46676702 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.58 0.53 2.2e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9733 0.519 rs72704603 chr1:150707992 C/T cg15448220 chr1:150897856 SETDB1 0.43 6.77 0.34 5.77e-11 Tonsillectomy; LIHC cis rs6701037 0.512 rs4650716 chr1:175128711 C/A cg17845761 chr1:175162550 KIAA0040 0.41 7.01 0.35 1.26e-11 Alcohol dependence; LIHC cis rs1451375 0.617 rs10271341 chr7:50591583 A/C cg14593290 chr7:50529359 DDC 0.62 9.78 0.47 4.43e-20 Malaria; LIHC cis rs79839061 0.610 rs73207794 chr4:872020 T/C cg07828340 chr4:882639 GAK 0.83 7.02 0.36 1.18e-11 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25212763 chr13:113532716 ATP11A -0.38 -6.07 -0.31 3.36e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9858542 0.953 rs6446272 chr3:49463287 G/A cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2066819 1.000 rs116535779 chr12:56739261 A/G cg26714650 chr12:56694279 CS -1.21 -14.74 -0.62 1.97e-38 Psoriasis vulgaris; LIHC cis rs6733011 0.508 rs6542843 chr2:99533729 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.77 -0.34 5.45e-11 Bipolar disorder; LIHC cis rs7208859 0.623 rs9890558 chr17:29110355 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2834188 1.000 rs1018742 chr21:34686381 A/G cg14352951 chr21:34696688 IFNAR1 0.47 6.43 0.33 4.24e-10 Narcolepsy; LIHC trans rs2727020 0.658 rs7120136 chr11:49384358 A/C cg15704280 chr7:45808275 SEPT13 -0.95 -19.18 -0.72 3.53e-56 Coronary artery disease; LIHC cis rs16858210 0.647 rs12107414 chr3:183574548 G/C cg25686905 chr3:183603175 PARL -0.52 -9.26 -0.45 2.28e-18 Menopause (age at onset); LIHC cis rs13191362 1.000 rs35754151 chr6:163074867 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.74 6.37 0.33 6.03e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg03806693 chr22:41940476 POLR3H -0.91 -10.69 -0.5 3.46e-23 Vitiligo; LIHC trans rs116095464 0.510 rs73016876 chr5:244475 T/C cg00938859 chr5:1591904 SDHAP3 0.55 6.64 0.34 1.22e-10 Breast cancer; LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg21782813 chr7:2030301 MAD1L1 0.55 10.02 0.48 6.9e-21 Bipolar disorder and schizophrenia; LIHC cis rs1385374 0.858 rs10773578 chr12:129290026 G/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.7 0.38 1.46e-13 Systemic lupus erythematosus; LIHC cis rs1005277 0.540 rs116205409 chr10:38478970 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.28 -0.32 1.02e-9 Extrinsic epigenetic age acceleration; LIHC cis rs6570726 0.902 rs4895678 chr6:145935510 C/T cg23711669 chr6:146136114 FBXO30 0.53 9.01 0.44 1.44e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs9902453 0.765 rs2264302 chr17:28057095 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -13.61 -0.59 5.27e-34 Coffee consumption (cups per day); LIHC cis rs916888 0.773 rs199534 chr17:44824213 T/G cg15921436 chr17:44337874 NA 0.64 6.54 0.33 2.31e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2976388 0.609 rs2572909 chr8:143806464 C/G cg06565975 chr8:143823917 SLURP1 0.34 6.69 0.34 8.92e-11 Urinary tract infection frequency; LIHC cis rs4423214 1.000 rs12789751 chr11:71164471 G/A cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg02353165 chr6:42928485 GNMT 0.6 8.96 0.44 2.21e-17 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01889020 chr15:66545863 MEGF11 0.5 6.36 0.33 6.43e-10 Hepatitis; LIHC cis rs11098699 0.821 rs904712 chr4:124225337 T/C cg09941581 chr4:124220074 SPATA5 0.33 6.57 0.33 1.86e-10 Mosquito bite size; LIHC cis rs9660992 0.573 rs1318187 chr1:205206172 T/A cg21545522 chr1:205238299 TMCC2 0.37 7.1 0.36 7.18e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs6570726 0.643 rs9403735 chr6:145936591 C/T cg13319975 chr6:146136371 FBXO30 -0.43 -6.78 -0.34 5.4e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1005277 0.579 rs2504148 chr10:38400788 A/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.659 rs4002655 chr12:38169881 T/G cg26384229 chr12:38710491 ALG10B 0.82 10.25 0.48 1.14e-21 Bladder cancer; LIHC cis rs9902453 1.000 rs4465649 chr17:28394747 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.85 -0.54 2.3e-27 Coffee consumption (cups per day); LIHC cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg08219700 chr8:58056026 NA 0.46 5.78 0.3 1.71e-8 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg23758822 chr17:41437982 NA 0.94 17.57 0.69 1.1e-49 Menopause (age at onset); LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -6.97 -0.35 1.59e-11 Total body bone mineral density; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg11563264 chr4:190862026 FRG1 -0.45 -6.14 -0.32 2.33e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6429082 0.818 rs167092 chr1:235642359 A/G cg26050004 chr1:235667680 B3GALNT2 0.5 7.9 0.39 3.97e-14 Adiposity; LIHC cis rs8044868 0.530 rs2287999 chr16:72059149 A/G cg16558253 chr16:72132732 DHX38 -0.36 -5.87 -0.3 1.05e-8 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg24503407 chr1:205819492 PM20D1 0.73 10.37 0.49 4.46e-22 Menarche (age at onset); LIHC cis rs875971 0.862 rs2420173 chr7:65645399 A/T cg18252515 chr7:66147081 NA 0.42 5.77 0.3 1.79e-8 Aortic root size; LIHC cis rs2236918 1.000 rs2236919 chr1:242017731 A/G cg17736920 chr1:242011382 EXO1 0.6 9.11 0.44 7.04e-18 Menopause (age at onset); LIHC cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg11644478 chr21:40555479 PSMG1 -0.37 -5.99 -0.31 5.18e-9 Menarche (age at onset); LIHC cis rs36051895 0.623 rs11506293 chr9:5257430 A/G cg02405213 chr9:5042618 JAK2 -0.61 -9.79 -0.47 3.96e-20 Pediatric autoimmune diseases; LIHC cis rs4727027 0.840 rs12670633 chr7:148796707 G/A cg23583168 chr7:148888333 NA -0.7 -9.81 -0.47 3.58e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs709400 0.593 rs12898029 chr14:103877884 T/C cg26031613 chr14:104095156 KLC1 -0.73 -9.55 -0.46 2.53e-19 Body mass index; LIHC cis rs2635047 0.638 rs2668760 chr18:44682891 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.91 0.3 8.09e-9 Educational attainment; LIHC cis rs2302190 0.882 rs9903173 chr17:56607358 C/T cg12560992 chr17:57184187 TRIM37 0.65 8.51 0.42 5.46e-16 Vitamin D levels; LIHC cis rs7264396 0.635 rs3827030 chr20:34474947 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.64 10.53 0.49 1.22e-22 Total cholesterol levels; LIHC cis rs6088590 1.000 rs6087623 chr20:33317662 C/G cg08999081 chr20:33150536 PIGU 0.37 5.77 0.3 1.81e-8 Coronary artery disease; LIHC cis rs7647973 0.696 rs7100 chr3:49053219 A/G cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.29 0.32 9.49e-10 Menarche (age at onset); LIHC cis rs3204270 0.759 rs62075725 chr17:79611510 A/G cg18367735 chr17:79674897 NA 0.69 7.75 0.39 1.09e-13 Dental caries; LIHC cis rs12701220 0.520 rs7803208 chr7:1162084 C/T cg04025307 chr7:1156635 C7orf50 0.53 8.19 0.4 5.29e-15 Bronchopulmonary dysplasia; LIHC cis rs2288073 0.965 rs6545338 chr2:24422156 C/T cg06627628 chr2:24431161 ITSN2 -0.62 -8.23 -0.41 3.95e-15 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs4268898 0.662 rs2891380 chr2:24525830 G/A cg06627628 chr2:24431161 ITSN2 -0.72 -9.81 -0.47 3.52e-20 Asthma; LIHC cis rs11671005 0.532 rs35983901 chr19:59016790 G/A cg25952890 chr19:58913133 NA 0.64 6.47 0.33 3.4e-10 Mean platelet volume; LIHC cis rs12478296 1.000 rs6743297 chr2:243013814 A/G cg18898632 chr2:242989856 NA -0.47 -6.44 -0.33 4e-10 Obesity-related traits; LIHC cis rs7584330 0.955 rs6729659 chr2:238385126 T/C cg14458575 chr2:238380390 NA 0.37 6.02 0.31 4.57e-9 Prostate cancer; LIHC cis rs8180040 0.764 rs11130115 chr3:47181661 C/A cg16586182 chr3:47516702 SCAP -0.5 -8.93 -0.43 2.66e-17 Colorectal cancer; LIHC cis rs16828019 0.929 rs35883594 chr1:41744093 A/G cg03962019 chr1:41807865 NA 0.52 7.28 0.37 2.27e-12 Intelligence (multi-trait analysis); LIHC cis rs2050392 0.624 rs303449 chr10:30726845 G/A cg25182066 chr10:30743637 MAP3K8 -0.62 -10.02 -0.48 7.09e-21 Inflammatory bowel disease; LIHC cis rs16854884 0.632 rs34038325 chr3:143685097 G/A cg06585982 chr3:143692056 C3orf58 0.58 7.79 0.39 8.18e-14 Economic and political preferences (feminism/equality); LIHC cis rs1983891 0.955 rs9381076 chr6:41517564 G/A cg15051332 chr6:41514432 FOXP4 0.41 5.72 0.3 2.32e-8 Prostate cancer; LIHC cis rs425277 0.606 rs377283 chr1:2075570 T/C cg24578937 chr1:2090814 PRKCZ 0.32 5.9 0.3 8.85e-9 Height; LIHC cis rs9733 0.818 rs4970926 chr1:150673684 T/C cg18016565 chr1:150552671 MCL1 -0.5 -10.31 -0.49 6.9e-22 Tonsillectomy; LIHC cis rs7927771 0.756 rs10742803 chr11:47439938 A/G cg20135002 chr11:47629003 NA 0.55 9.32 0.45 1.45e-18 Subjective well-being; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10994681 chr11:31672091 ELP4 0.3 6.39 0.33 5.52e-10 Cognitive function; LIHC cis rs11098499 0.954 rs67265404 chr4:120359270 C/T cg09307838 chr4:120376055 NA 0.77 12.14 0.55 1.93e-28 Corneal astigmatism; LIHC cis rs769267 0.929 rs2905424 chr19:19473445 T/C cg03709012 chr19:19516395 GATAD2A -0.99 -16.89 -0.67 5.71e-47 Tonsillectomy; LIHC cis rs8180040 0.764 rs11708451 chr3:47198826 G/A cg27129171 chr3:47204927 SETD2 0.69 12.11 0.55 2.57e-28 Colorectal cancer; LIHC trans rs208515 0.525 rs10755508 chr6:66675790 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.75 8.71 0.43 1.36e-16 Exhaled nitric oxide levels; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg26338869 chr17:61819248 STRADA 0.6 8.83 0.43 5.67e-17 Prudent dietary pattern; LIHC cis rs7833790 1.000 rs7833384 chr8:82730915 T/C cg27398817 chr8:82754497 SNX16 -0.41 -7.2 -0.36 3.76e-12 Diastolic blood pressure; LIHC cis rs2153535 0.580 rs7767756 chr6:8453428 A/C cg23788917 chr6:8435910 SLC35B3 0.6 8.59 0.42 3.03e-16 Motion sickness; LIHC cis rs1707322 0.928 rs7527244 chr1:46368772 A/G cg03146154 chr1:46216737 IPP 0.48 7.61 0.38 2.76e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6500602 0.702 rs9929475 chr16:4540885 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.49 -7.23 -0.36 3.25e-12 Schizophrenia; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC cis rs3806933 0.522 rs12521169 chr5:110448313 G/A cg04022379 chr5:110408740 TSLP 0.6 9.92 0.47 1.5e-20 Eosinophilic esophagitis; LIHC cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9596863 0.898 rs8000553 chr13:54344501 C/T ch.13.53330881F chr13:54432880 NA 0.45 6.1 0.31 2.94e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs62244186 0.606 rs6798590 chr3:44556861 T/A cg25364880 chr3:44379878 C3orf23 0.57 7.89 0.39 4.26e-14 Depressive symptoms; LIHC cis rs798554 1.000 rs798550 chr7:2760609 A/G cg04166393 chr7:2884313 GNA12 0.43 5.92 0.3 7.89e-9 Height; LIHC cis rs61990749 0.597 rs176952 chr14:78180736 T/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.81 -0.39 6.91e-14 Fibroblast growth factor basic levels; LIHC cis rs2991971 0.967 rs2356551 chr1:46009318 C/T cg15605315 chr1:45957053 TESK2 0.47 6.4 0.33 5.13e-10 High light scatter reticulocyte count; LIHC cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg13395646 chr4:1353034 KIAA1530 0.41 6.49 0.33 2.97e-10 Obesity-related traits; LIHC cis rs10876993 0.890 rs774887 chr12:58034835 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.24 -0.32 1.29e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs3784262 0.839 rs1579744 chr15:58229523 G/A cg12031962 chr15:58353849 ALDH1A2 0.31 6.04 0.31 4.1e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs5769765 0.955 rs9616368 chr22:50303533 C/G cg09182678 chr22:50328711 NA -0.43 -6.09 -0.31 2.99e-9 Schizophrenia; LIHC cis rs7647973 0.925 rs6808036 chr3:49236439 T/G cg07636037 chr3:49044803 WDR6 0.51 6.51 0.33 2.63e-10 Menarche (age at onset); LIHC trans rs1552244 0.572 rs59132826 chr3:10169725 G/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs67311347 1.000 rs56992941 chr3:40472434 A/T cg09455208 chr3:40491958 NA 0.34 6.94 0.35 1.97e-11 Renal cell carcinoma; LIHC cis rs11626933 1.000 rs7146724 chr14:90766092 C/T cg07150772 chr14:90864620 CALM1 -0.42 -5.89 -0.3 9.19e-9 Gut microbiota (bacterial taxa); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13546538 chr9:111754815 CTNNAL1 0.46 6.07 0.31 3.47e-9 Hepatitis; LIHC cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.47 0.46 4.67e-19 Bipolar disorder; LIHC cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg02931644 chr1:25747376 RHCE 0.34 7.41 0.37 1.02e-12 Erythrocyte sedimentation rate; LIHC cis rs597539 0.652 rs579136 chr11:68637476 C/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.08e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7945705 0.791 rs4579928 chr11:8815704 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.38 6.56 0.33 2.03e-10 Hemoglobin concentration; LIHC cis rs3796619 1.000 rs4045481 chr4:1090625 C/T cg27284194 chr4:1044797 NA 0.62 10.47 0.49 1.93e-22 Recombination rate (males); LIHC cis rs758324 0.947 rs6596039 chr5:131198652 C/A cg06307176 chr5:131281290 NA 0.4 5.81 0.3 1.42e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg12463550 chr7:65579703 CRCP 0.68 7.27 0.37 2.49e-12 Diabetic kidney disease; LIHC cis rs477692 1.000 rs577227 chr10:131404528 C/T cg05714579 chr10:131428358 MGMT 0.46 7.68 0.38 1.7e-13 Response to temozolomide; LIHC cis rs611744 0.625 rs11779824 chr8:109278689 G/A cg18478394 chr8:109455254 TTC35 0.44 7.57 0.38 3.6e-13 Dupuytren's disease; LIHC trans rs61931739 0.517 rs10772139 chr12:34186178 A/T cg26384229 chr12:38710491 ALG10B 0.6 7.67 0.38 1.83e-13 Morning vs. evening chronotype; LIHC cis rs769267 0.930 rs2301786 chr19:19413947 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.61 9.57 0.46 2.3e-19 Tonsillectomy; LIHC trans rs4927850 0.881 rs7630489 chr3:195753401 T/C cg16724585 chr3:197361211 NA -0.46 -6.44 -0.33 4.17e-10 Pancreatic cancer; LIHC cis rs7572733 0.515 rs12619300 chr2:198786490 A/C cg00792783 chr2:198669748 PLCL1 -0.46 -6.79 -0.34 5.11e-11 Dermatomyositis; LIHC cis rs9583531 0.600 rs7330080 chr13:111367115 C/T cg24331049 chr13:111365604 ING1 0.64 10.7 0.5 3.05e-23 Coronary artery disease; LIHC cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg03517284 chr6:25882590 NA 0.59 8.37 0.41 1.45e-15 Blood metabolite levels; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.92 0.57 2.17e-31 Prudent dietary pattern; LIHC cis rs7249142 0.549 rs2283623 chr19:19283027 G/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.35 -5.75 -0.3 1.95e-8 IgG glycosylation; LIHC cis rs6840360 0.571 rs11726892 chr4:152555106 A/G cg22705602 chr4:152727874 NA -0.32 -6.26 -0.32 1.17e-9 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.851 rs12936646 chr17:37647450 A/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.34 -0.59 5.58e-33 Glomerular filtration rate (creatinine); LIHC cis rs11785400 0.793 rs4301430 chr8:143737416 A/G cg10596483 chr8:143751796 JRK 0.48 7.75 0.39 1.08e-13 Schizophrenia; LIHC trans rs1005277 0.540 rs2474598 chr10:38430296 C/T cg27523141 chr10:43048294 ZNF37B -0.36 -6.27 -0.32 1.11e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12079745 0.590 rs9628661 chr1:169310283 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.79 -7.08 -0.36 8.09e-12 QT interval; LIHC cis rs8017423 1.000 rs8017423 chr14:90679910 A/G cg04374321 chr14:90722782 PSMC1 0.75 14.5 0.62 1.82e-37 Mortality in heart failure; LIHC cis rs870825 0.616 rs7678864 chr4:185635158 C/T cg04058563 chr4:185651563 MLF1IP 0.69 7.21 0.36 3.66e-12 Blood protein levels; LIHC trans rs3858145 0.588 rs7081284 chr10:70044792 C/G cg04882175 chr6:131122610 NA -0.51 -6.09 -0.31 3.06e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs634534 0.561 rs655744 chr11:65776585 G/T cg02427764 chr11:65769310 BANF1;EIF1AD -0.53 -8.98 -0.44 1.91e-17 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs4713118 0.869 rs9393851 chr6:27699581 A/T cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs9902453 0.904 rs7213076 chr17:28419428 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.69 -10.89 -0.51 6.6e-24 Coffee consumption (cups per day); LIHC cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg27170947 chr2:26402098 FAM59B -0.67 -8.3 -0.41 2.49e-15 Gut microbiome composition (summer); LIHC cis rs3862030 0.503 rs6584505 chr10:104254412 C/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.66 0.56 2.23e-30 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs11711311 1.000 rs9828099 chr3:113518402 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.01 0.44 1.52e-17 IgG glycosylation; LIHC cis rs17021463 0.726 rs62320444 chr4:95261251 C/T cg11021082 chr4:95130006 SMARCAD1 0.45 8.28 0.41 2.85e-15 Testicular germ cell tumor; LIHC cis rs3741151 1.000 rs111882289 chr11:73053714 T/C cg17517138 chr11:73019481 ARHGEF17 0.92 6.78 0.34 5.32e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs4555082 0.872 rs7153832 chr14:105730563 G/T cg10792982 chr14:105748885 BRF1 0.44 6.02 0.31 4.43e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.72 13.23 0.58 1.55e-32 Prudent dietary pattern; LIHC cis rs17776563 0.922 rs12148331 chr15:89110081 C/T cg05013243 chr15:89149849 MIR1179 0.47 7.74 0.39 1.09e-13 Thyroid hormone levels; LIHC cis rs763121 0.853 rs5750626 chr22:38977890 G/C cg21395723 chr22:39101663 GTPBP1 0.37 5.83 0.3 1.27e-8 Menopause (age at onset); LIHC trans rs9388451 0.839 rs4897155 chr6:126095144 C/A cg05039488 chr6:79577232 IRAK1BP1 -0.54 -8.64 -0.42 2.13e-16 Brugada syndrome; LIHC cis rs17253792 0.545 rs34136598 chr14:56013238 C/T cg01858014 chr14:56050164 KTN1 -0.63 -5.87 -0.3 1.03e-8 Putamen volume; LIHC cis rs6539247 0.583 rs880297 chr12:106443266 C/T cg20883310 chr12:106464547 NUAK1 0.45 7.43 0.37 8.62e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs7107174 1.000 rs7111986 chr11:78102266 G/T cg02023728 chr11:77925099 USP35 0.46 8.51 0.42 5.64e-16 Testicular germ cell tumor; LIHC trans rs7613875 0.620 rs17657664 chr3:50032008 T/G cg21665057 chr3:196295764 WDR53;FBXO45 0.43 6.57 0.33 1.84e-10 Body mass index; LIHC cis rs8060686 0.641 rs112099181 chr16:68154230 T/C cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.66e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs5753037 0.547 rs140140 chr22:30166437 G/A cg01021169 chr22:30184971 ASCC2 -0.41 -7.99 -0.4 2.08e-14 Type 1 diabetes; LIHC cis rs7528419 0.927 rs660240 chr1:109817838 T/C cg00908766 chr1:109817496 CELSR2 0.46 8.19 0.41 5.13e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs9900497 0.504 rs2228100 chr17:19642952 C/G cg22552966 chr17:19620595 SLC47A2 0.48 10.29 0.49 8.23e-22 Response to paliperidone in schizophrenia (CGI-S score); LIHC cis rs7192750 0.617 rs9929256 chr16:72040032 A/C cg14768367 chr16:72042858 DHODH 0.55 5.73 0.3 2.22e-8 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg19774624 chr17:42201019 HDAC5 -0.81 -12.53 -0.56 6.69e-30 Total body bone mineral density; LIHC cis rs477692 1.000 rs473771 chr10:131408155 A/C cg19680672 chr10:131412579 MGMT -0.46 -7.01 -0.35 1.29e-11 Response to temozolomide; LIHC cis rs9640161 0.830 rs3757423 chr7:150067714 A/G cg21361702 chr7:150065534 REPIN1 -0.54 -7.81 -0.39 7.12e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.12 0.55 2.3e-28 Prudent dietary pattern; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21792150 chr3:101567884 NFKBIZ -0.58 -6.65 -0.34 1.19e-10 Systolic blood pressure; LIHC cis rs17401966 0.838 rs12127604 chr1:10352800 T/G cg19773385 chr1:10388646 KIF1B -0.41 -7.39 -0.37 1.16e-12 Hepatocellular carcinoma; LIHC cis rs11997175 0.550 rs7459534 chr8:33836623 G/C ch.8.33884649F chr8:33765107 NA 0.36 5.78 0.3 1.69e-8 Body mass index; LIHC cis rs1577917 1.000 rs10455158 chr6:86672825 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.55 -0.33 2.08e-10 Response to antipsychotic treatment; LIHC cis rs763121 0.853 rs5757187 chr22:39021522 A/G cg06022373 chr22:39101656 GTPBP1 -0.67 -11.9 -0.54 1.46e-27 Menopause (age at onset); LIHC cis rs9443645 0.901 rs2174742 chr6:79610101 G/T cg05283184 chr6:79620031 NA -0.33 -5.73 -0.3 2.15e-8 Intelligence (multi-trait analysis); LIHC cis rs4268898 0.527 rs72789910 chr2:24388609 T/G cg06627628 chr2:24431161 ITSN2 -0.68 -8.54 -0.42 4.61e-16 Asthma; LIHC cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg00166722 chr3:10149974 C3orf24 0.47 5.86 0.3 1.12e-8 Alzheimer's disease; LIHC cis rs798554 0.679 rs2533868 chr7:2886559 G/A cg13628971 chr7:2884303 GNA12 0.59 10.13 0.48 2.84e-21 Height; LIHC cis rs8072100 0.905 rs8078686 chr17:45735706 T/C cg08085267 chr17:45401833 C17orf57 0.57 8.28 0.41 2.76e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs8114671 0.562 rs6119536 chr20:33450041 A/G cg07148914 chr20:33460835 GGT7 -0.58 -9.1 -0.44 7.58e-18 Height; LIHC cis rs992157 0.698 rs6746089 chr2:219170377 A/G cg00012203 chr2:219082015 ARPC2 0.81 13.14 0.58 3.16e-32 Colorectal cancer; LIHC trans rs2243480 1.000 rs313814 chr7:65503293 C/A cg10756647 chr7:56101905 PSPH 1.08 13.46 0.59 2e-33 Diabetic kidney disease; LIHC cis rs9916302 0.904 rs7503705 chr17:37669704 A/G cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs4819052 0.851 rs2838855 chr21:46680566 C/G cg22633049 chr21:46681294 NA 0.37 6.41 0.33 4.78e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1707322 1.000 rs7553924 chr1:46352624 T/C cg03146154 chr1:46216737 IPP 0.47 7.68 0.38 1.69e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3770081 1.000 rs6750765 chr2:86300308 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.86 -8.52 -0.42 5.12e-16 Facial emotion recognition (sad faces); LIHC cis rs801193 0.569 rs2013908 chr7:66121069 A/T cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs477692 0.624 rs880300 chr10:131329486 G/A cg19680672 chr10:131412579 MGMT -0.39 -5.98 -0.31 5.5e-9 Response to temozolomide; LIHC cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.97 -14.86 -0.63 6.92e-39 Gut microbiome composition (summer); LIHC cis rs7605378 0.528 rs1704191 chr2:200816393 C/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.52 6.83 0.35 3.85e-11 Osteoporosis; LIHC cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg07424592 chr7:64974309 NA 0.84 9.67 0.46 1.07e-19 Diabetic kidney disease; LIHC cis rs77637988 0.631 rs7573316 chr2:48600692 C/T cg00032884 chr2:48540671 FOXN2 0.41 6.43 0.33 4.38e-10 Joint mobility (Beighton score); LIHC cis rs7520050 0.966 rs10789481 chr1:46383583 C/G cg03146154 chr1:46216737 IPP -0.37 -5.9 -0.3 8.66e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6977660 0.714 rs10251774 chr7:19790489 T/C cg07541023 chr7:19748670 TWISTNB 0.49 7.28 0.37 2.36e-12 Thyroid stimulating hormone; LIHC cis rs4144743 1.000 rs72823474 chr17:45321776 G/C cg18085866 chr17:45331354 ITGB3 -0.57 -8.21 -0.41 4.51e-15 Body mass index; LIHC cis rs1997103 0.906 rs6593231 chr7:55402914 T/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00949670 chr12:120967105 COQ5 0.49 6.72 0.34 7.53e-11 Pancreatic cancer; LIHC cis rs2274273 1.000 rs10149435 chr14:55627489 C/T cg01864836 chr14:55583639 NA -0.35 -6.01 -0.31 4.68e-9 Protein biomarker; LIHC cis rs7107174 1.000 rs1893447 chr11:77973182 A/G cg02023728 chr11:77925099 USP35 0.45 8.74 0.43 1.07e-16 Testicular germ cell tumor; LIHC cis rs6604026 0.555 rs3790450 chr1:93091065 A/G cg13858687 chr1:93297071 RPL5 0.6 5.71 0.3 2.41e-8 Multiple sclerosis; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg27286337 chr10:134555280 INPP5A 0.93 13.32 0.58 6.93e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10838708 1.000 rs10838708 chr11:47441513 G/A cg20135002 chr11:47629003 NA -0.44 -7.06 -0.36 9.38e-12 Height; LIHC cis rs2066819 1.000 rs808919 chr12:56647911 C/G cg26734620 chr12:56694298 CS -0.89 -9.01 -0.44 1.45e-17 Psoriasis vulgaris; LIHC cis rs636291 0.517 rs11121579 chr1:10541824 G/C cg17425144 chr1:10567563 PEX14 0.53 10.14 0.48 2.59e-21 Prostate cancer; LIHC trans rs6489882 0.763 rs1859329 chr12:113376452 C/T cg10175203 chr3:128143634 NA 0.38 6.17 0.32 1.96e-9 Chronic lymphocytic leukemia; LIHC cis rs9916302 0.706 rs8073907 chr17:37424149 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -11.86 -0.54 2.03e-27 Glomerular filtration rate (creatinine); LIHC cis rs7106204 0.748 rs4382909 chr11:24236618 C/T ch.11.24196551F chr11:24239977 NA 0.79 11.36 0.52 1.43e-25 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2842992 1.000 rs2842992 chr6:160071159 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.34 0.52 1.64e-25 Age-related macular degeneration (geographic atrophy); LIHC cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.47 0.33 3.39e-10 Mean platelet volume; LIHC trans rs7937682 0.961 rs17113227 chr11:111620491 A/G cg18187862 chr3:45730750 SACM1L 0.56 6.49 0.33 2.99e-10 Primary sclerosing cholangitis; LIHC cis rs7633770 0.749 rs6442011 chr3:46685722 C/T cg11219411 chr3:46661640 NA 0.45 8.08 0.4 1.1e-14 Coronary artery disease; LIHC cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg23758822 chr17:41437982 NA 0.94 17.91 0.7 4.65e-51 Menopause (age at onset); LIHC cis rs2153535 0.563 rs7739249 chr6:8534590 C/G cg23788917 chr6:8435910 SLC35B3 0.61 8.94 0.44 2.53e-17 Motion sickness; LIHC cis rs644799 0.601 rs7902 chr11:95565288 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.63 9.5 0.46 3.84e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.42 -0.33 4.61e-10 Total body bone mineral density; LIHC cis rs4819052 0.851 rs10470247 chr21:46659018 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.52 0.53 3.51e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs77861329 1.000 rs13314125 chr3:52115398 C/T cg08692210 chr3:52188851 WDR51A 0.82 7.39 0.37 1.17e-12 Macrophage inflammatory protein 1b levels; LIHC cis rs748404 0.578 rs576557 chr15:43597737 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.96 0.44 2.19e-17 Lung cancer; LIHC cis rs9814567 1.000 rs2177601 chr3:134245434 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4332037 0.851 rs10268609 chr7:1962163 A/C cg23422044 chr7:1970798 MAD1L1 -0.6 -6.96 -0.35 1.73e-11 Bipolar disorder; LIHC cis rs10504229 0.593 rs58647001 chr8:58025132 G/A cg20607798 chr8:58055168 NA 0.45 6.35 0.32 6.93e-10 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg18230493 chr5:56204884 C5orf35 -0.46 -6.45 -0.33 3.88e-10 Initial pursuit acceleration; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg21724239 chr8:58056113 NA 0.59 7.44 0.37 8.3e-13 Developmental language disorder (linguistic errors); LIHC trans rs6952808 0.825 rs34922657 chr7:1938655 C/T cg04565464 chr8:145669602 NFKBIL2 0.4 6.15 0.32 2.16e-9 Bipolar disorder and schizophrenia; LIHC cis rs6942756 1.000 rs2402945 chr7:128956256 C/A cg02491457 chr7:128862824 NA -0.63 -9.0 -0.44 1.58e-17 White matter hyperintensity burden; LIHC cis rs11098499 0.710 rs6851130 chr4:120133712 G/A cg09307838 chr4:120376055 NA -0.49 -7.54 -0.38 4.38e-13 Corneal astigmatism; LIHC cis rs60871478 1.000 rs62432899 chr7:826542 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.52 6.02 0.31 4.48e-9 Cerebrospinal P-tau181p levels; LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg09455208 chr3:40491958 NA 0.4 8.1 0.4 9.51e-15 Renal cell carcinoma; LIHC cis rs6912958 0.535 rs1753153 chr6:88032834 T/G cg08069147 chr6:88032118 GJB7;C6orf162 0.6 11.37 0.52 1.21e-25 Monocyte percentage of white cells; LIHC cis rs34779708 0.966 rs34296409 chr10:35404613 C/G cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg25742201 chr17:35306863 AATF -0.54 -6.11 -0.31 2.67e-9 Bronchial neuroendocrine tumor; LIHC trans rs61931739 0.534 rs10844791 chr12:34211659 C/T cg26384229 chr12:38710491 ALG10B 0.59 7.57 0.38 3.5e-13 Morning vs. evening chronotype; LIHC cis rs1568889 1.000 rs61889027 chr11:28281908 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.76 0.34 5.81e-11 Bipolar disorder; LIHC cis rs4906332 0.834 rs12882130 chr14:103878774 C/G cg19000871 chr14:103996768 TRMT61A -0.38 -6.16 -0.32 2.08e-9 Coronary artery disease; LIHC cis rs1348850 0.567 rs2222711 chr2:178534110 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.94 0.39 2.88e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs6968419 0.802 rs6978849 chr7:115809732 A/C cg00405060 chr16:4016306 ADCY9 -0.43 -6.53 -0.33 2.38e-10 Intraocular pressure; LIHC trans rs4714291 0.674 rs3008837 chr6:40046725 C/T cg02267698 chr19:7991119 CTXN1 -0.4 -6.74 -0.34 6.89e-11 Strep throat; LIHC cis rs2731664 0.792 rs335432 chr5:176866258 G/A cg23176889 chr5:176863531 GRK6 -0.7 -12.48 -0.56 9.96e-30 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg20295408 chr7:1910781 MAD1L1 -0.51 -7.38 -0.37 1.23e-12 Bipolar disorder and schizophrenia; LIHC trans rs208515 0.525 rs1351866 chr6:66696969 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.83 0.43 5.71e-17 Exhaled nitric oxide levels; LIHC cis rs8044868 0.530 rs9928157 chr16:72117073 T/C cg16558253 chr16:72132732 DHX38 -0.38 -6.49 -0.33 2.98e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs35306767 0.903 rs7914758 chr10:891702 T/C cg20503657 chr10:835505 NA 1.35 14.76 0.62 1.75e-38 Eosinophil percentage of granulocytes; LIHC trans rs1814175 0.817 rs1851860 chr11:49861310 A/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.17 -0.78 4.65e-72 Height; LIHC cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg11301795 chr4:187892539 NA -0.26 -7.16 -0.36 4.97e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.720 rs7752286 chr6:146072662 C/T cg23711669 chr6:146136114 FBXO30 -0.73 -13.51 -0.59 1.28e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs7149337 0.869 rs10137445 chr14:51694416 G/A cg23942311 chr14:51606299 NA 0.31 6.16 0.32 2.01e-9 Cancer; LIHC cis rs6088590 0.931 rs6088617 chr20:33408036 G/A cg06115741 chr20:33292138 TP53INP2 0.59 8.18 0.4 5.51e-15 Coronary artery disease; LIHC cis rs9549367 0.713 rs9549682 chr13:113830181 C/T cg18105134 chr13:113819100 PROZ -0.76 -13.02 -0.58 9.81e-32 Platelet distribution width; LIHC cis rs3806843 0.933 rs2240696 chr5:140168070 A/G cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7508 0.511 rs208025 chr8:17878170 A/G cg01800426 chr8:17659068 MTUS1 -0.4 -6.02 -0.31 4.45e-9 Atrial fibrillation; LIHC cis rs4500972 1 rs4500972 chr2:73767897 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.86 -0.35 3.31e-11 Glomerular filtration rate (creatinine); LIHC cis rs1949733 0.656 rs6845969 chr4:8402465 A/T cg11789530 chr4:8429930 ACOX3 0.77 11.39 0.52 1.06e-25 Response to antineoplastic agents; LIHC cis rs9311474 0.632 rs6445528 chr3:52572447 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.49 -6.8 -0.34 4.76e-11 Electroencephalogram traits; LIHC cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg16497277 chr3:49208875 KLHDC8B -0.51 -6.39 -0.33 5.44e-10 Menarche (age at onset); LIHC cis rs67311347 0.956 rs12633446 chr3:40505661 G/A cg09455208 chr3:40491958 NA -0.36 -7.23 -0.36 3.18e-12 Renal cell carcinoma; LIHC cis rs904251 0.523 rs9349039 chr6:37480392 A/G cg08126542 chr6:37504118 NA -0.37 -6.33 -0.32 7.78e-10 Cognitive performance; LIHC cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg22029157 chr1:209979665 IRF6 0.44 7.1 0.36 7.26e-12 Cleft lip with or without cleft palate; LIHC cis rs9715521 0.775 rs62301198 chr4:59848776 C/T cg11281224 chr4:60001000 NA -0.31 -5.73 -0.3 2.24e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14405528 chr22:47372700 TBC1D22A -0.43 -6.08 -0.31 3.3e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.875 rs2814871 chr6:146312274 G/T cg23711669 chr6:146136114 FBXO30 0.6 10.25 0.48 1.09e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs66573146 0.572 rs68169399 chr4:6952491 T/A cg07817883 chr1:32538562 TMEM39B 1.02 9.01 0.44 1.54e-17 Granulocyte percentage of myeloid white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08905662 chr7:102789948 NAPEPLD 0.46 6.86 0.35 3.25e-11 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08413153 chr17:46185283 SNX11 0.42 6.26 0.32 1.14e-9 Pancreatic cancer; LIHC cis rs9549367 0.789 rs9577220 chr13:113908294 T/A cg18105134 chr13:113819100 PROZ -0.58 -10.29 -0.49 8.43e-22 Platelet distribution width; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15877295 chr7:138915876 UBN2 0.4 6.33 0.32 7.84e-10 Cognitive function; LIHC cis rs6545883 0.859 rs7561672 chr2:61519094 G/A cg14146966 chr2:61757674 XPO1 -0.43 -7.25 -0.37 2.76e-12 Tuberculosis; LIHC cis rs6754311 0.551 rs10928545 chr2:136501840 A/G cg15123519 chr2:136567270 LCT 0.39 7.22 0.36 3.36e-12 Mosquito bite size; LIHC cis rs7264396 1.000 rs224424 chr20:34147998 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.88 -0.35 2.94e-11 Total cholesterol levels; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg18538332 chr22:24372958 LOC391322 0.63 9.7 0.46 8.21e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2952156 1.000 rs2952156 chr17:37876835 A/G cg00129232 chr17:37814104 STARD3 -0.48 -8.6 -0.42 2.96e-16 Asthma; LIHC cis rs11711311 1.000 rs13073843 chr3:113449150 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.05 -0.36 9.75e-12 IgG glycosylation; LIHC cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg00091569 chr3:40428383 ENTPD3 0.39 6.45 0.33 3.9e-10 Renal cell carcinoma; LIHC cis rs17152411 0.895 rs7079153 chr10:126587146 C/G cg07906193 chr10:126599966 NA 0.42 6.62 0.34 1.35e-10 Height; LIHC cis rs7100689 0.577 rs10749550 chr10:82031197 A/G cg00277334 chr10:82204260 NA -0.52 -6.32 -0.32 8.01e-10 Post bronchodilator FEV1; LIHC trans rs259842 0.800 rs6725456 chr2:180718419 C/T cg03498402 chr16:67219437 EXOC3L 0.43 6.1 0.31 2.9e-9 Blood protein levels; LIHC cis rs17125944 0.505 rs75296244 chr14:53233218 G/A cg13660082 chr14:53194042 PSMC6 -0.46 -7.54 -0.38 4.22e-13 Alzheimer's disease (late onset); LIHC cis rs7487075 0.558 rs4768692 chr12:46639635 T/C cg15584813 chr12:47219626 SLC38A4 0.32 5.94 0.31 7.04e-9 Itch intensity from mosquito bite; LIHC cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg07636037 chr3:49044803 WDR6 0.75 12.43 0.56 1.57e-29 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs57221529 0.709 rs72703090 chr5:598314 C/T cg09021430 chr5:549028 NA -0.42 -8.36 -0.41 1.65e-15 Lung disease severity in cystic fibrosis; LIHC cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.39e-8 Menopause (age at onset); LIHC cis rs2549003 1.000 rs2070725 chr5:131821788 C/T cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs2288073 0.801 rs10175668 chr2:24367275 G/A cg06627628 chr2:24431161 ITSN2 -0.52 -6.97 -0.35 1.66e-11 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs2153535 0.580 rs1577467 chr6:8444241 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs2304069 0.545 rs7445660 chr5:149413610 A/C cg22760475 chr5:149380129 HMGXB3;TIGD6 0.59 8.33 0.41 1.94e-15 HIV-1 control; LIHC cis rs6545883 0.929 rs2593627 chr2:61618574 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.45 -0.37 7.93e-13 Tuberculosis; LIHC cis rs870825 0.860 rs72703526 chr4:185605676 A/T cg04058563 chr4:185651563 MLF1IP 0.76 6.49 0.33 3.05e-10 Blood protein levels; LIHC cis rs249954 0.512 rs35633 chr16:23704005 C/T cg05131483 chr16:23706242 ERN2 0.36 5.88 0.3 9.92e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs11098499 0.731 rs9995026 chr4:120490499 T/A cg25214090 chr10:38739885 LOC399744 0.57 9.39 0.45 9.01e-19 Corneal astigmatism; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg17024643 chr1:214725274 PTPN14 -0.41 -6.6 -0.34 1.55e-10 Triglycerides; LIHC cis rs1008375 0.898 rs61047804 chr4:17593965 G/A cg16339924 chr4:17578868 LAP3 0.46 6.43 0.33 4.32e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs66887589 1.000 rs66887589 chr4:120509279 T/C cg25214090 chr10:38739885 LOC399744 -0.4 -6.39 -0.33 5.31e-10 Diastolic blood pressure; LIHC cis rs72781680 0.898 rs72788212 chr2:24087385 G/A cg08917208 chr2:24149416 ATAD2B 0.88 8.29 0.41 2.69e-15 Lymphocyte counts; LIHC cis rs912057 0.671 rs1294417 chr6:6741932 T/C cg06612196 chr6:6737390 NA 0.53 9.91 0.47 1.63e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs10464366 0.544 rs34866559 chr7:39166071 G/A cg18850127 chr7:39170497 POU6F2 0.46 8.09 0.4 1.04e-14 IgG glycosylation; LIHC cis rs9733 0.596 rs2175615 chr1:150624101 A/G cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg13607699 chr17:42295918 UBTF -0.44 -6.9 -0.35 2.6e-11 Total body bone mineral density; LIHC cis rs826838 0.868 rs864324 chr12:39122853 A/G cg26384229 chr12:38710491 ALG10B 0.44 6.87 0.35 3.05e-11 Heart rate; LIHC cis rs1348850 0.567 rs1405714 chr2:178538584 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.61 -8.53 -0.42 4.93e-16 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7771547 0.573 rs9470278 chr6:36399239 G/A cg07856975 chr6:36356162 ETV7 -0.36 -5.86 -0.3 1.08e-8 Platelet distribution width; LIHC cis rs708547 0.836 rs1713997 chr4:57843863 G/C cg16868167 chr4:57843880 C4orf14;POLR2B 0.79 14.15 0.61 4.33e-36 Response to bleomycin (chromatid breaks); LIHC cis rs4665809 1.000 rs4665820 chr2:26309150 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.99 -0.44 1.69e-17 Gut microbiome composition (summer); LIHC cis rs748404 0.578 rs510108 chr15:43605439 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.58 10.4 0.49 3.38e-22 Lung cancer; LIHC cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg05025164 chr4:1340916 KIAA1530 0.42 6.36 0.33 6.49e-10 Obesity-related traits; LIHC cis rs240764 0.658 rs2132168 chr6:101178491 G/A cg12253828 chr6:101329408 ASCC3 -0.41 -6.43 -0.33 4.31e-10 Neuroticism; LIHC cis rs2979489 0.891 rs4733495 chr8:30366883 A/G cg26383811 chr8:30366931 RBPMS 0.76 13.09 0.58 5.09e-32 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs2425143 1.000 rs1056196 chr20:34327159 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.84 -0.3 1.2e-8 Blood protein levels; LIHC cis rs2549003 1.000 rs10214312 chr5:131821866 T/G cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs4742903 0.935 rs1413341 chr9:106973013 C/T cg14250997 chr9:106856677 SMC2 0.34 5.73 0.3 2.19e-8 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg12516959 chr21:47718080 NA -0.4 -6.43 -0.33 4.34e-10 Testicular germ cell tumor; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg00280220 chr17:61926910 NA 0.43 6.77 0.34 5.78e-11 Prudent dietary pattern; LIHC cis rs903552 1.000 rs11634912 chr15:102005510 A/G cg25677261 chr15:102009856 PCSK6 -0.46 -6.22 -0.32 1.44e-9 Diabetic kidney disease; LIHC cis rs12497850 0.931 rs9311430 chr3:48845251 C/T cg06212747 chr3:49208901 KLHDC8B 0.55 7.12 0.36 6.57e-12 Parkinson's disease; LIHC cis rs10876993 0.928 rs10877008 chr12:58103592 A/G cg15848620 chr12:58087721 OS9 -0.54 -7.35 -0.37 1.46e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs7534824 0.625 rs61780285 chr1:101357627 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 7.07 0.36 8.81e-12 Refractive astigmatism; LIHC cis rs2380220 0.606 rs7754906 chr6:95992429 C/T cg04719120 chr6:96025338 MANEA 0.51 6.51 0.33 2.66e-10 Behavioural disinhibition (generation interaction); LIHC cis rs7103648 0.838 rs11039244 chr11:47466442 G/A cg20307385 chr11:47447363 PSMC3 1.04 17.54 0.69 1.36e-49 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg21782813 chr7:2030301 MAD1L1 0.47 7.96 0.4 2.63e-14 Bipolar disorder and schizophrenia; LIHC cis rs6748734 0.779 rs6437371 chr2:241797424 G/C cg09990169 chr2:241835740 C2orf54 -0.65 -10.47 -0.49 1.97e-22 Urinary metabolites; LIHC cis rs17253792 0.822 rs10137364 chr14:56059987 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs7503807 0.837 rs9915667 chr17:78754340 A/G cg09596252 chr17:78655493 RPTOR -0.42 -7.46 -0.37 7.43e-13 Obesity; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg00091569 chr3:40428383 ENTPD3 -0.33 -5.81 -0.3 1.41e-8 Renal cell carcinoma; LIHC cis rs6754311 0.731 rs309134 chr2:136755684 A/G cg15123519 chr2:136567270 LCT 0.36 7.19 0.36 3.99e-12 Mosquito bite size; LIHC cis rs1538970 0.924 rs12046816 chr1:45891543 G/T cg24296786 chr1:45957014 TESK2 -0.49 -7.14 -0.36 5.74e-12 Platelet count; LIHC cis rs4911259 0.513 rs6057665 chr20:31463460 A/G cg13636640 chr20:31349939 DNMT3B -0.61 -10.78 -0.5 1.56e-23 Inflammatory bowel disease; LIHC cis rs35306767 0.903 rs12769873 chr10:936526 G/T cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC trans rs634534 0.622 rs531612 chr11:65705432 C/T cg17712092 chr4:129076599 LARP1B -0.72 -11.71 -0.53 7.35e-27 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs2404602 0.503 rs284909 chr15:76736628 C/T cg23625390 chr15:77176239 SCAPER 0.41 6.92 0.35 2.26e-11 Blood metabolite levels; LIHC trans rs561341 1.000 rs8064843 chr17:30245744 A/G cg20587970 chr11:113659929 NA -0.6 -6.89 -0.35 2.76e-11 Hip circumference adjusted for BMI; LIHC cis rs1267303 0.642 rs114746843 chr1:46999239 C/A cg25110126 chr1:46999211 NA 0.48 6.48 0.33 3.12e-10 Monobrow; LIHC cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg06481639 chr22:41940642 POLR3H -0.61 -5.9 -0.3 8.79e-9 Vitiligo; LIHC cis rs1816752 0.905 rs6490927 chr13:25013940 C/G cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T ch.1.1079286F chr1:33292969 S100PBP -0.45 -7.38 -0.37 1.23e-12 Hepatitis; LIHC cis rs9303401 0.659 rs12602389 chr17:56779778 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg24879335 chr3:133465180 TF 0.28 6.31 0.32 8.88e-10 Iron status biomarkers; LIHC cis rs2153535 0.547 rs9502720 chr6:8541362 C/A cg07606381 chr6:8435919 SLC35B3 0.78 11.28 0.52 2.74e-25 Motion sickness; LIHC cis rs9921222 0.502 rs28461430 chr16:369562 G/A cg26944245 chr16:421049 TMEM8A;MRPL28 0.42 6.89 0.35 2.61e-11 Bone mineral density (spine);Bone mineral density; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg21581312 chr15:35529473 LOC723972 0.4 6.09 0.31 2.99e-9 Bilirubin levels; LIHC cis rs76419734 0.510 rs2216515 chr4:106750214 C/T cg24545054 chr4:106630052 GSTCD;INTS12 -0.71 -7.43 -0.37 8.53e-13 Post bronchodilator FEV1; LIHC cis rs2933343 1.000 rs1683811 chr3:128612113 A/C cg25356066 chr3:128598488 ACAD9 0.54 7.21 0.36 3.62e-12 IgG glycosylation; LIHC cis rs875971 0.862 rs6964437 chr7:65686444 A/G cg18876405 chr7:65276391 NA -0.35 -6.39 -0.33 5.29e-10 Aortic root size; LIHC cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.84e-10 Diabetic kidney disease; LIHC cis rs10838687 0.736 rs2633083 chr11:47249420 T/C cg25783544 chr11:47291846 MADD -0.47 -5.9 -0.3 8.83e-9 Proinsulin levels; LIHC cis rs9296092 0.560 rs9469511 chr6:33530930 T/G cg13560919 chr6:33536144 NA -0.39 -6.41 -0.33 4.74e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs782590 0.764 rs2586969 chr2:55829392 G/C cg03859395 chr2:55845619 SMEK2 0.72 11.75 0.54 5.37e-27 Metabolic syndrome; LIHC cis rs9457247 1.000 rs365189 chr6:167384545 G/A cg23791538 chr6:167370224 RNASET2 -0.67 -11.63 -0.53 1.44e-26 Crohn's disease; LIHC cis rs1982963 0.585 rs61971558 chr14:52496024 G/A cg10843707 chr14:52510701 NID2 0.42 6.15 0.32 2.13e-9 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10959786 chr13:74708124 KLF12 0.4 6.36 0.33 6.37e-10 Cognitive function; LIHC cis rs8014204 0.747 rs2070598 chr14:75360906 C/T cg08847533 chr14:75593920 NEK9 -0.37 -6.24 -0.32 1.3e-9 Caffeine consumption; LIHC cis rs6952808 0.965 rs11768541 chr7:1894884 G/A cg20295408 chr7:1910781 MAD1L1 -0.53 -7.58 -0.38 3.37e-13 Bipolar disorder and schizophrenia; LIHC cis rs7107174 0.681 rs10793301 chr11:78020913 G/T cg02023728 chr11:77925099 USP35 0.53 9.99 0.48 8.91e-21 Testicular germ cell tumor; LIHC cis rs735860 0.726 rs209518 chr6:53208016 C/A cg10236188 chr6:53219634 NA 0.42 7.83 0.39 6.26e-14 Glaucoma; LIHC cis rs798554 0.610 rs2248390 chr7:2855594 T/C cg13628971 chr7:2884303 GNA12 0.43 6.77 0.34 5.57e-11 Height; LIHC cis rs5753618 0.539 rs2228619 chr22:31663842 C/G cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs6088590 0.707 rs67159833 chr20:33488079 T/C cg24642439 chr20:33292090 TP53INP2 0.78 10.16 0.48 2.37e-21 Coronary artery disease; LIHC cis rs34779708 0.733 rs4007271 chr10:35546611 C/T cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs797680 0.789 rs797671 chr1:93700363 C/A cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.89 0.3 9.29e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs3796352 1.000 rs11706035 chr3:53011868 A/T cg07884673 chr3:53033167 SFMBT1 0.91 6.6 0.34 1.58e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg11764359 chr7:65958608 NA 0.59 6.26 0.32 1.18e-9 Diabetic kidney disease; LIHC cis rs34375054 0.738 rs10773145 chr12:125625603 C/T cg25124228 chr12:125621409 AACS 0.41 7.01 0.35 1.24e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg22963979 chr7:1858916 MAD1L1 -0.41 -6.5 -0.33 2.91e-10 Bipolar disorder and schizophrenia; LIHC cis rs9921222 0.597 rs3848369 chr16:415078 C/T cg12437481 chr16:420112 MRPL28 -0.75 -11.92 -0.54 1.24e-27 Bone mineral density (spine);Bone mineral density; LIHC cis rs2658782 0.547 rs4344448 chr11:93047047 T/C cg15737290 chr11:93063684 CCDC67 0.46 6.11 0.31 2.76e-9 Pulmonary function decline; LIHC trans rs9929218 1.000 rs12446575 chr16:68791644 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.64 -9.62 -0.46 1.5e-19 Colorectal cancer; LIHC cis rs12477438 0.765 rs10181422 chr2:99558970 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.44 -0.49 2.4e-22 Chronic sinus infection; LIHC cis rs1008375 0.800 rs62296338 chr4:17613425 G/T cg02297831 chr4:17616191 MED28 0.46 7.18 0.36 4.31e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17685 0.515 rs111240556 chr7:75600863 T/C cg16684958 chr7:75615977 POR 0.39 6.1 0.31 2.8e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1568889 1.000 rs12797712 chr11:28290890 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.84 0.35 3.59e-11 Bipolar disorder; LIHC cis rs4820539 1.000 rs885964 chr22:23461003 G/C cg21100191 chr22:23484243 RTDR1 0.9 16.17 0.66 4.42e-44 Bone mineral density; LIHC cis rs6570726 0.791 rs9373463 chr6:145894762 C/T cg23711669 chr6:146136114 FBXO30 0.71 12.68 0.57 1.87e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs6547741 0.874 rs58737572 chr2:27852118 A/C cg27432699 chr2:27873401 GPN1 0.78 12.83 0.57 5.04e-31 Oral cavity cancer; LIHC cis rs17401966 0.931 rs12131441 chr1:10428952 G/A cg15208524 chr1:10270712 KIF1B 0.41 6.16 0.32 2.03e-9 Hepatocellular carcinoma; LIHC cis rs986417 1.000 rs761555 chr14:61109543 T/C cg27398547 chr14:60952738 C14orf39 0.65 6.47 0.33 3.43e-10 Gut microbiota (bacterial taxa); LIHC cis rs4853012 0.838 rs58759652 chr2:74344902 A/T cg20891558 chr2:74357851 NA 0.82 16.98 0.68 2.5e-47 Gestational age at birth (maternal effect); LIHC cis rs10256972 0.684 rs2363279 chr7:1096143 A/G cg07092213 chr7:1199455 ZFAND2A -0.45 -6.5 -0.33 2.8e-10 Longevity;Endometriosis; LIHC cis rs17270561 0.583 rs12662869 chr6:25784481 A/C cg17691542 chr6:26056736 HIST1H1C -0.46 -6.25 -0.32 1.24e-9 Iron status biomarkers; LIHC cis rs523522 0.962 rs4767905 chr12:120930835 C/T cg27279351 chr12:120934652 DYNLL1 0.67 12.11 0.55 2.53e-28 High light scatter reticulocyte count; LIHC cis rs6582630 0.519 rs11181526 chr12:38360230 A/G cg26384229 chr12:38710491 ALG10B 0.57 7.88 0.39 4.37e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs1707322 1.000 rs12097761 chr1:46291162 T/C cg03146154 chr1:46216737 IPP 0.48 7.68 0.38 1.68e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07390141 chr15:93427738 NA -0.36 -6.96 -0.35 1.73e-11 Cognitive function; LIHC cis rs709400 1.000 rs56660916 chr14:104126137 G/T cg26031613 chr14:104095156 KLC1 1.06 14.25 0.61 1.67e-36 Body mass index; LIHC cis rs116095464 0.558 rs7708515 chr5:234989 C/G cg22857025 chr5:266934 NA -1.4 -17.27 -0.68 1.77e-48 Breast cancer; LIHC cis rs1113500 0.933 rs2077259 chr1:108629551 T/C cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.92e-12 Growth-regulated protein alpha levels; LIHC cis rs1005277 0.540 rs2224248 chr10:38451886 A/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2933343 0.649 rs789216 chr3:128594503 A/C cg24203234 chr3:128598194 ACAD9 0.45 6.27 0.32 1.07e-9 IgG glycosylation; LIHC trans rs11644362 0.576 rs35738878 chr16:12981880 T/C cg14384093 chr9:111878565 C9orf5 -0.29 -6.21 -0.32 1.5e-9 Positive affect;Subjective well-being; LIHC trans rs12960119 0.536 rs12956263 chr18:23726864 C/A cg05333146 chr16:67183725 B3GNT9 0.64 6.06 0.31 3.57e-9 Rhegmatogenous retinal detachment; LIHC cis rs7917772 0.503 rs7100753 chr10:104300979 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.05 0.58 7.17e-32 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg09455208 chr3:40491958 NA 0.35 7.01 0.35 1.25e-11 Renal cell carcinoma; LIHC cis rs2153535 0.505 rs1737583 chr6:8536812 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.62e-15 Motion sickness; LIHC cis rs11958404 0.932 rs72816552 chr5:157422376 G/A cg05962755 chr5:157440814 NA 0.97 10.53 0.49 1.19e-22 IgG glycosylation; LIHC cis rs9814567 1.000 rs13081177 chr3:134289860 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.25 0.55 7.29e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10911363 0.592 rs2761581 chr1:183474850 G/C cg09173681 chr1:183549694 NCF2 0.54 9.49 0.46 4.03e-19 Systemic lupus erythematosus; LIHC cis rs1448094 0.512 rs7953318 chr12:86245929 G/A cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC cis rs9649213 0.593 rs55825602 chr7:98013039 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.8 -0.3 1.51e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs10751667 0.621 rs11246345 chr11:934924 T/C ch.11.42038R chr11:967971 AP2A2 0.53 9.58 0.46 2.01e-19 Alzheimer's disease (late onset); LIHC cis rs2760061 0.659 rs708107 chr1:228189495 C/T cg01200585 chr1:228362443 C1orf69 0.41 6.26 0.32 1.14e-9 Diastolic blood pressure; LIHC cis rs2153535 0.580 rs9406171 chr6:8515362 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.26e-27 Motion sickness; LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs763121 0.925 rs5757165 chr22:38994577 C/T cg14440974 chr22:39074834 NA -0.36 -6.06 -0.31 3.56e-9 Menopause (age at onset); LIHC trans rs66887589 0.967 rs7678973 chr4:120511817 T/C cg25214090 chr10:38739885 LOC399744 -0.39 -6.37 -0.33 6.04e-10 Diastolic blood pressure; LIHC cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg26818010 chr10:134567672 INPP5A -0.8 -9.85 -0.47 2.56e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1059312 0.545 rs12303387 chr12:129276733 C/T cg09035930 chr12:129282057 SLC15A4 -0.52 -7.95 -0.39 2.75e-14 Systemic lupus erythematosus; LIHC cis rs10892173 0.545 rs115865940 chr11:117666711 C/T cg21640587 chr11:117668038 DSCAML1 0.55 6.9 0.35 2.58e-11 Myopia; LIHC cis rs2153535 0.580 rs9392220 chr6:8457946 G/A cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs9486719 1.000 rs12529248 chr6:96895377 T/G cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs4319547 1.000 rs9705654 chr12:123083508 T/C cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.06 -0.4 1.29e-14 Body mass index; LIHC cis rs7772486 0.846 rs866473 chr6:146353414 A/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.13 -0.31 2.37e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088590 1.000 rs12626122 chr20:33425800 A/G cg06115741 chr20:33292138 TP53INP2 0.63 8.6 0.42 2.86e-16 Coronary artery disease; LIHC cis rs13223928 0.516 rs1872880 chr7:3148389 G/C cg19214707 chr7:3157722 NA -0.36 -6.6 -0.34 1.6e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs9457247 0.663 rs9457258 chr6:167444254 T/C cg12798992 chr6:167411361 FGFR1OP 0.53 8.66 0.42 1.87e-16 Crohn's disease; LIHC cis rs67478160 0.572 rs8015603 chr14:104293678 C/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.35 0.56 3.25e-29 Schizophrenia; LIHC trans rs9914544 0.564 rs4334348 chr17:18787004 G/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.57 -0.33 1.82e-10 Educational attainment (years of education); LIHC cis rs894734 0.535 rs10783613 chr12:54321966 G/T cg17708016 chr12:54321992 NA 0.41 7.26 0.37 2.68e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs2237234 0.542 rs7755997 chr6:26483048 G/A cg09904177 chr6:26538194 HMGN4 0.46 7.9 0.39 3.78e-14 Autism spectrum disorder or schizophrenia; LIHC cis rs798554 1.000 rs798559 chr7:2758341 T/C cg13628971 chr7:2884303 GNA12 0.48 6.88 0.35 2.94e-11 Height; LIHC cis rs2204008 0.744 rs8186814 chr12:38335169 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.57e-15 Bladder cancer; LIHC cis rs3099143 1.000 rs10431768 chr15:77162158 A/G cg21673338 chr15:77095150 SCAPER 0.49 7.64 0.38 2.23e-13 Recalcitrant atopic dermatitis; LIHC cis rs8017423 0.647 rs12882973 chr14:90820502 G/A cg04374321 chr14:90722782 PSMC1 -0.5 -7.39 -0.37 1.12e-12 Mortality in heart failure; LIHC cis rs9733 0.519 rs11800855 chr1:150800995 G/A cg18016565 chr1:150552671 MCL1 0.5 9.62 0.46 1.5700000000000001e-19 Tonsillectomy; LIHC cis rs7103648 1.000 rs7947450 chr11:47429904 G/A cg20307385 chr11:47447363 PSMC3 1.03 18.02 0.7 1.6e-51 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs1008375 0.900 rs7658447 chr4:17579415 T/C cg16339924 chr4:17578868 LAP3 0.58 7.5 0.38 5.46e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8077889 0.917 rs60335331 chr17:41907509 A/G cg26893861 chr17:41843967 DUSP3 0.95 11.14 0.52 8.8e-25 Triglycerides; LIHC cis rs1348850 0.914 rs4893938 chr2:178250095 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.84 13.06 0.58 6.4e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs600806 0.888 rs10745352 chr1:109871787 T/C cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.34 -0.37 1.61e-12 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.96e-16 Prudent dietary pattern; LIHC cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg02564969 chr6:151773285 C6orf211;RMND1 0.52 7.99 0.4 2.09e-14 Menarche (age at onset); LIHC cis rs6542838 0.702 rs4851167 chr2:99496303 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.44 -6.37 -0.33 5.95e-10 Fear of minor pain; LIHC cis rs1008375 1.000 rs4698634 chr4:17630192 A/C cg02297831 chr4:17616191 MED28 -0.49 -7.76 -0.39 9.88e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1395 1.000 rs1275537 chr2:27441302 C/G cg23587288 chr2:27483067 SLC30A3 -0.3 -5.83 -0.3 1.25e-8 Blood metabolite levels; LIHC cis rs1552244 0.882 rs68153882 chr3:10013110 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg11494091 chr17:61959527 GH2 0.42 7.9 0.39 3.73e-14 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg05368731 chr17:41323189 NBR1 0.72 12.06 0.55 3.69e-28 Menopause (age at onset); LIHC cis rs12477438 0.765 rs9710648 chr2:99673129 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs9527 0.615 rs7096452 chr10:104736563 G/A cg15744005 chr10:104629667 AS3MT -0.3 -6.1 -0.31 2.9e-9 Arsenic metabolism; LIHC cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 8.52 0.42 5.2e-16 Platelet count; LIHC cis rs9303280 0.806 rs11078927 chr17:38064405 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.04 0.36 1.04e-11 Self-reported allergy; LIHC cis rs66573146 0.808 rs55942328 chr4:6990960 T/G cg00086871 chr4:6988644 TBC1D14 0.88 5.96 0.31 6.31e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2637266 0.935 rs2579727 chr10:78395497 A/C cg18941641 chr10:78392320 NA 0.29 6.4 0.33 5.23e-10 Pulmonary function; LIHC cis rs2070488 1.000 rs1002675 chr3:38445226 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.85 0.65 8.24e-43 Electrocardiographic conduction measures; LIHC cis rs2645694 0.626 rs2703126 chr4:77819842 T/C cg03477792 chr4:77819574 ANKRD56 0.6 8.77 0.43 8.32e-17 Emphysema distribution in smoking; LIHC cis rs600626 0.578 rs11821808 chr11:75451187 C/T cg24262691 chr11:75473276 NA 0.43 6.5 0.33 2.9e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC trans rs3960554 0.932 rs4728597 chr7:75821062 C/T cg19862616 chr7:65841803 NCRNA00174 0.56 7.5 0.38 5.66e-13 Eotaxin levels; LIHC cis rs2050392 0.517 rs160017 chr10:30772894 A/G cg02070205 chr10:30722105 MAP3K8 -0.43 -5.79 -0.3 1.63e-8 Inflammatory bowel disease; LIHC cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg00149659 chr3:10157352 C3orf10 0.68 6.93 0.35 2.11e-11 Alzheimer's disease; LIHC cis rs4631830 0.720 rs2611512 chr10:51515534 A/G cg20129853 chr10:51489980 NA -0.39 -8.56 -0.42 3.77e-16 Prostate-specific antigen levels; LIHC cis rs10481151 1.000 rs10481151 chr8:124831834 A/G cg02993010 chr8:124780839 FAM91A1 -0.5 -5.73 -0.3 2.23e-8 Cognitive performance; LIHC cis rs7635838 0.718 rs2594979 chr3:11381910 T/G cg00170343 chr3:11313890 ATG7 0.6 10.0 0.48 7.8e-21 HDL cholesterol; LIHC cis rs950169 0.763 rs35372971 chr15:84941795 G/A cg03959625 chr15:84868606 LOC388152 0.47 6.6 0.34 1.52e-10 Schizophrenia; LIHC cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg09417038 chr21:47716443 C21orf57 0.63 9.44 0.45 5.85e-19 Testicular germ cell tumor; LIHC cis rs6089584 0.927 rs6089593 chr20:60572312 G/A cg12751644 chr20:60527061 NA -0.36 -5.94 -0.31 7.17e-9 Body mass index; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg23788167 chr9:74979561 ZFAND5 0.43 6.13 0.31 2.46e-9 Hepatitis; LIHC cis rs8049040 1.000 rs7197127 chr16:71473836 G/A cg06353428 chr16:71660113 MARVELD3 -0.61 -6.28 -0.32 1.02e-9 Blood protein levels; LIHC cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg16262614 chr3:133464971 TF 0.28 6.39 0.33 5.36e-10 Iron status biomarkers; LIHC cis rs523522 0.962 rs11065149 chr12:120956963 G/A cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs9486715 1.000 rs3798297 chr6:97062835 C/T cg06623918 chr6:96969491 KIAA0776 -0.84 -13.99 -0.6 1.73e-35 Headache; LIHC trans rs12960119 0.536 rs34503500 chr18:23728195 G/A cg05333146 chr16:67183725 B3GNT9 0.64 6.06 0.31 3.57e-9 Rhegmatogenous retinal detachment; LIHC cis rs2629540 0.765 rs12221075 chr10:126534855 G/A cg08799069 chr10:126477246 METTL10 -0.49 -8.19 -0.4 5.31e-15 Cocaine dependence; LIHC cis rs644148 0.836 rs2686774 chr19:44999827 T/C cg15540054 chr19:45004280 ZNF180 -0.76 -11.46 -0.53 5.97e-26 Personality dimensions; LIHC cis rs17384381 0.859 rs12724823 chr1:85906385 G/T cg16011679 chr1:85725395 C1orf52 0.83 8.9 0.43 3.24e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.69 9.95 0.47 1.14e-20 Lymphocyte counts; LIHC cis rs7618915 1.000 rs3852063 chr3:52349204 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.38 5.85 0.3 1.18e-8 Bipolar disorder; LIHC cis rs10911232 0.507 rs10911206 chr1:183012423 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.01e-22 Hypertriglyceridemia; LIHC cis rs4665809 0.652 rs6728090 chr2:26524726 C/T cg27170947 chr2:26402098 FAM59B -0.55 -7.25 -0.37 2.79e-12 Gut microbiome composition (summer); LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg14709524 chr16:89940631 TCF25 0.58 7.44 0.37 8.46e-13 Skin colour saturation; LIHC cis rs9790314 1.000 rs3849524 chr3:161015589 C/T cg03342759 chr3:160939853 NMD3 -0.68 -8.44 -0.42 9.09e-16 Morning vs. evening chronotype; LIHC cis rs2859741 0.967 rs522481 chr1:37488337 C/T cg09363841 chr1:37513479 NA -0.19 -5.99 -0.31 5.28e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs986417 1.000 rs3931460 chr14:60939101 A/C cg27398547 chr14:60952738 C14orf39 0.75 8.5 0.42 5.86e-16 Gut microbiota (bacterial taxa); LIHC cis rs9790314 0.586 rs11713185 chr3:161111357 C/G cg03342759 chr3:160939853 NMD3 -0.54 -8.54 -0.42 4.4e-16 Morning vs. evening chronotype; LIHC cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg00106254 chr7:1943704 MAD1L1 -0.4 -6.55 -0.33 2.06e-10 Schizophrenia; LIHC trans rs4332037 1.000 rs10240470 chr7:1949971 G/T cg11693508 chr17:37793320 STARD3 -0.67 -7.26 -0.37 2.66e-12 Bipolar disorder; LIHC cis rs8017423 0.967 rs17188605 chr14:90722579 C/T cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.18e-41 Mortality in heart failure; LIHC cis rs477692 0.673 rs579952 chr10:131356084 A/T cg05714579 chr10:131428358 MGMT -0.38 -6.15 -0.32 2.17e-9 Response to temozolomide; LIHC cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg26818010 chr10:134567672 INPP5A -0.8 -9.7 -0.46 8.04e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8062405 0.755 rs12445823 chr16:28588049 A/C cg07382826 chr16:28625726 SULT1A1 0.5 7.73 0.39 1.19e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08585897 chr16:75680535 KARS;TERF2IP 0.5 6.35 0.32 6.93e-10 Systolic blood pressure; LIHC cis rs17666538 0.585 rs1669733 chr8:606696 C/T cg07234876 chr8:600039 NA -0.91 -7.79 -0.39 7.8500000000000006e-14 IgG glycosylation; LIHC cis rs10838687 0.669 rs830084 chr11:47251652 T/C cg25783544 chr11:47291846 MADD -0.47 -5.92 -0.3 7.95e-9 Proinsulin levels; LIHC cis rs1559088 0.895 rs13345542 chr19:33586739 G/C cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7552404 1.000 rs4949875 chr1:76173080 G/A cg22875332 chr1:76189707 ACADM 0.47 6.74 0.34 6.6e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg02290350 chr8:58132656 NA 0.48 9.33 0.45 1.38e-18 Developmental language disorder (linguistic errors); LIHC cis rs4073582 0.595 rs1115508 chr11:65923149 A/G cg16950941 chr11:66035639 RAB1B 0.53 7.99 0.4 2.04e-14 Gout; LIHC cis rs477692 0.624 rs880300 chr10:131329486 G/A cg05714579 chr10:131428358 MGMT 0.39 6.25 0.32 1.19e-9 Response to temozolomide; LIHC cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 11.17 0.52 6.87e-25 Platelet count; LIHC trans rs4820294 0.669 rs35662099 chr22:38053909 C/T cg19894588 chr14:64061835 NA -0.46 -7.4 -0.37 1.08e-12 Fat distribution (HIV); LIHC cis rs1005277 0.563 rs2505215 chr10:38481273 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.28 -0.32 1.02e-9 Extrinsic epigenetic age acceleration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23374814 chr5:72292757 FCHO2 -0.43 -6.25 -0.32 1.22e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4908768 0.501 rs2016084 chr1:8613418 C/A cg20416874 chr1:8611966 RERE -0.68 -14.82 -0.63 1.02e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7772486 0.875 rs2748482 chr6:146336532 T/C cg05347473 chr6:146136440 FBXO30 0.37 6.0 0.31 4.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1348850 0.526 rs7607073 chr2:178375065 C/A cg27490568 chr2:178487706 NA 1.11 12.08 0.55 3.25e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs778371 0.659 rs2289911 chr2:233704252 A/G cg08000102 chr2:233561755 GIGYF2 -0.77 -9.35 -0.45 1.18e-18 Schizophrenia; LIHC cis rs6582630 0.555 rs7969922 chr12:38529491 C/T cg26384229 chr12:38710491 ALG10B 0.68 9.61 0.46 1.59e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs9911578 1.000 rs7342903 chr17:56914588 C/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.83 -0.43 5.37e-17 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.897 rs7373778 chr3:48836392 C/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.23 0.36 3.26e-12 Parkinson's disease; LIHC cis rs10492096 0.947 rs12371184 chr12:6632925 A/G cg13857086 chr12:6580257 VAMP1 0.56 6.27 0.32 1.06e-9 Hip geometry; LIHC cis rs17270561 0.887 rs12201170 chr6:25866247 A/G cg16482183 chr6:26056742 HIST1H1C 0.59 6.84 0.35 3.71e-11 Iron status biomarkers; LIHC cis rs908922 0.676 rs7550769 chr1:152531213 G/A cg20991723 chr1:152506922 NA 0.53 8.76 0.43 9.49e-17 Hair morphology; LIHC cis rs12464559 0.522 rs6749823 chr2:152565055 C/T cg01189475 chr2:152685088 ARL5A 0.68 8.08 0.4 1.15e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7586673 1.000 rs7586673 chr2:161923520 C/A cg22496339 chr2:162101262 NA 0.68 10.39 0.49 3.8e-22 Intelligence (multi-trait analysis); LIHC cis rs950169 0.580 rs11634320 chr15:85172183 A/C cg12863693 chr15:85201151 NMB -0.48 -7.04 -0.36 1.03e-11 Schizophrenia; LIHC cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Bipolar disorder; LIHC cis rs72843506 0.722 rs78041331 chr17:20208846 G/T cg12065943 chr17:19881925 AKAP10 -0.38 -6.26 -0.32 1.15e-9 Schizophrenia; LIHC cis rs7772486 0.754 rs9373476 chr6:146139741 C/G cg23711669 chr6:146136114 FBXO30 0.66 12.02 0.54 5.37e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769765 0.773 rs138861 chr22:50202276 A/G cg26441486 chr22:50317300 CRELD2 0.38 6.22 0.32 1.45e-9 Schizophrenia; LIHC cis rs907683 0.584 rs1058284 chr2:220286142 G/A cg15015639 chr2:220282977 DES -0.37 -9.03 -0.44 1.29e-17 Resting heart rate; LIHC cis rs7582720 1.000 rs72928609 chr2:203837573 G/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs3820928 0.605 rs6748311 chr2:227792530 T/A cg16088116 chr21:44841560 SIK1 -0.39 -6.09 -0.31 2.98e-9 Pulmonary function; LIHC trans rs1814175 0.645 rs4411280 chr11:49962750 A/G cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09717979 chr4:103790325 UBE2D3;CISD2 0.46 6.13 0.31 2.38e-9 Lung function (FEV1/FVC); LIHC cis rs881375 0.692 rs2072438 chr9:123651301 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.79 0.34 4.99e-11 Rheumatoid arthritis; LIHC cis rs10744422 1.000 rs3817094 chr12:123332032 T/C cg22842854 chr12:123319900 HIP1R -0.74 -9.76 -0.47 5.03e-20 Schizophrenia; LIHC trans rs6500602 0.929 rs6500603 chr16:4497537 G/C cg05791018 chr13:19965014 NA -0.28 -6.16 -0.32 2e-9 Schizophrenia; LIHC cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg08392591 chr16:89556376 ANKRD11 0.41 6.14 0.32 2.31e-9 Multiple myeloma (IgH translocation); LIHC trans rs1814175 0.791 rs10769625 chr11:49869887 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.35 -0.78 8.99e-73 Height; LIHC cis rs2637266 0.703 rs2583062 chr10:78558472 T/C cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.96e-9 Pulmonary function; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg07677032 chr17:61819896 STRADA 0.43 6.25 0.32 1.24e-9 Prudent dietary pattern; LIHC trans rs875971 0.830 rs4718358 chr7:65973668 T/C cg10756647 chr7:56101905 PSPH 0.44 6.46 0.33 3.67e-10 Aortic root size; LIHC cis rs919433 0.963 rs12618612 chr2:198171058 G/T cg10820045 chr2:198174542 NA -0.58 -9.64 -0.46 1.29e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs922107 0.738 rs1031684 chr1:90051225 G/A cg15422784 chr1:90023713 LRRC8B -0.49 -7.77 -0.39 9.02e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs240764 0.817 rs239246 chr6:101089134 G/A cg09795085 chr6:101329169 ASCC3 0.53 7.54 0.38 4.18e-13 Neuroticism; LIHC cis rs77633900 0.614 rs2459360 chr15:76868664 C/T cg21673338 chr15:77095150 SCAPER -0.5 -7.32 -0.37 1.83e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs929354 0.742 rs1182396 chr7:157031831 A/C cg17757837 chr7:157058334 UBE3C -0.73 -11.96 -0.54 8.79e-28 Body mass index; LIHC cis rs12986413 0.874 rs4806832 chr19:2184652 C/T cg09261902 chr19:2140048 AP3D1 0.41 6.95 0.35 1.89e-11 Height; LIHC trans rs783540 0.967 rs783526 chr15:83285795 C/A cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.7 -0.34 8.41e-11 Schizophrenia; LIHC trans rs1973993 0.691 rs1989141 chr1:96898520 C/T cg10631902 chr5:14652156 NA 0.37 10.08 0.48 4.43e-21 Weight; LIHC cis rs12928939 0.520 rs8051760 chr16:71811098 C/A cg00732059 chr16:71740210 PHLPP2 -0.33 -5.8 -0.3 1.51e-8 Post bronchodilator FEV1; LIHC cis rs1035144 0.524 rs8009260 chr14:81408591 G/T cg06600135 chr14:81408086 NA 0.49 8.7 0.43 1.43e-16 Male sexual orientation; LIHC cis rs9733 0.596 rs1136808 chr1:150702717 G/C cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs929354 0.713 rs10085650 chr7:156993413 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs1190552 0.846 rs11160683 chr14:102933347 A/G cg10241871 chr14:102965420 TECPR2 -0.5 -7.88 -0.39 4.31e-14 Blood protein levels; LIHC cis rs4891159 0.790 rs689885 chr18:74110563 T/G cg24786174 chr18:74118243 ZNF516 0.78 14.4 0.61 4.42e-37 Longevity; LIHC cis rs11628318 0.802 rs6575926 chr14:103050183 G/A cg12046867 chr14:103022105 NA -0.59 -8.58 -0.42 3.25e-16 Platelet count; LIHC cis rs8044995 0.563 rs73613962 chr16:68361974 T/G cg03983715 chr16:68378420 PRMT7 -0.51 -5.95 -0.31 6.56e-9 Schizophrenia; LIHC cis rs748404 0.697 rs491804 chr15:43560825 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.39 0.41 1.28e-15 Lung cancer; LIHC cis rs7897654 0.571 rs12764049 chr10:104634956 A/G cg15744005 chr10:104629667 AS3MT -0.37 -7.62 -0.38 2.53e-13 Schizophrenia; LIHC cis rs7116495 1.000 rs493065 chr11:71796929 T/C cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs6831256 0.583 rs10937929 chr4:3483037 C/T cg17706124 chr4:3521738 LRPAP1 0.41 6.22 0.32 1.43e-9 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs250677 1.000 rs190378 chr5:148434275 G/T cg18129178 chr5:148520854 ABLIM3 -0.42 -6.85 -0.35 3.39e-11 Breast cancer; LIHC cis rs1728785 1.000 rs1728784 chr16:68591156 T/A cg02972257 chr16:68554789 NA -0.56 -6.4 -0.33 5.19e-10 Ulcerative colitis; LIHC cis rs2439831 1.000 rs2601014 chr15:43756013 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.62 7.72 0.39 1.27e-13 Lung cancer in ever smokers; LIHC cis rs2242116 0.932 rs7646906 chr3:46949379 G/A cg27129171 chr3:47204927 SETD2 0.48 7.67 0.38 1.82e-13 Birth weight; LIHC cis rs2243480 0.901 rs778730 chr7:65823325 T/A cg07424592 chr7:64974309 NA 0.79 9.2 0.45 3.71e-18 Diabetic kidney disease; LIHC cis rs4654899 1.000 rs4654905 chr1:21509558 A/G cg08539965 chr1:21396338 EIF4G3 0.33 5.87 0.3 1.04e-8 Superior frontal gyrus grey matter volume; LIHC cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg05368731 chr17:41323189 NBR1 0.73 12.63 0.56 2.82e-30 Menopause (age at onset); LIHC cis rs73001065 0.818 rs12610185 chr19:19721722 G/A cg03709012 chr19:19516395 GATAD2A 0.85 7.8 0.39 7.47e-14 LDL cholesterol; LIHC cis rs151997 1.000 rs42415 chr5:50207442 T/A cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25916527 chr5:72292534 FCHO2 0.42 6.33 0.32 7.67e-10 Longevity; LIHC cis rs921968 0.643 rs563268 chr2:219372912 T/G cg18887096 chr2:219472410 PLCD4 0.38 6.54 0.33 2.21e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20922377 chr15:48623205 DUT -0.56 -6.54 -0.33 2.25e-10 Systolic blood pressure; LIHC cis rs637571 0.522 rs7105628 chr11:65763067 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.04 0.44 1.15e-17 Eosinophil percentage of white cells; LIHC cis rs6449957 0.639 rs251397 chr5:67508511 A/G cg23036683 chr5:67512108 NA 0.52 7.62 0.38 2.54e-13 Cleft lip with or without cleft palate; LIHC trans rs3960554 0.808 rs112372188 chr7:75723376 G/A cg19862616 chr7:65841803 NCRNA00174 0.61 8.22 0.41 4.16e-15 Eotaxin levels; LIHC cis rs4727027 0.870 rs11525060 chr7:148801091 G/A cg23583168 chr7:148888333 NA -0.69 -9.7 -0.46 7.94e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs2727020 0.619 rs1164665 chr11:49295630 T/C cg03929089 chr4:120376271 NA 0.67 9.54 0.46 2.87e-19 Coronary artery disease; LIHC trans rs6108011 0.659 rs6108023 chr20:7590607 C/T cg13422339 chr21:47602486 C21orf56 0.52 6.08 0.31 3.29e-9 Hemostatic factors and hematological phenotypes; LIHC cis rs769267 0.895 rs2916069 chr19:19520358 A/G cg03709012 chr19:19516395 GATAD2A 1.02 18.13 0.7 5.95e-52 Tonsillectomy; LIHC cis rs11031096 0.678 rs11031184 chr11:4186192 C/T cg18678763 chr11:4115507 RRM1 -0.38 -5.88 -0.3 1e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs4714291 0.802 rs911818 chr6:39988816 C/A cg02267698 chr19:7991119 CTXN1 -0.39 -6.49 -0.33 3.07e-10 Strep throat; LIHC cis rs8078723 0.714 rs3859187 chr17:38150613 C/A cg17467752 chr17:38218738 THRA -0.59 -10.14 -0.48 2.77e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9517302 0.615 rs2274053 chr13:99098318 C/T cg22223119 chr13:99095684 FARP1 -0.6 -8.68 -0.43 1.59e-16 Obesity-related traits; LIHC cis rs2033711 0.837 rs3764535 chr19:58929052 G/A cg00825309 chr19:58991885 ZNF446 -0.6 -9.2 -0.45 3.53e-18 Uric acid clearance; LIHC cis rs2073499 0.935 rs2236939 chr3:50243510 G/T cg03645007 chr3:50255295 SLC38A3 0.5 6.89 0.35 2.66e-11 Schizophrenia; LIHC cis rs2228479 0.850 rs76075456 chr16:89834270 T/C cg19635926 chr16:89946313 TCF25 0.48 6.17 0.32 1.97e-9 Skin colour saturation; LIHC cis rs7772486 0.840 rs2777478 chr6:146309117 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.43 0.53 7.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs6547741 1.000 rs4666009 chr2:27857992 T/A cg27432699 chr2:27873401 GPN1 0.8 13.25 0.58 1.3e-32 Oral cavity cancer; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg21782813 chr7:2030301 MAD1L1 0.43 7.2 0.36 3.94e-12 Bipolar disorder and schizophrenia; LIHC cis rs17685 0.712 rs60232511 chr7:75800082 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.36 -0.33 6.6e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12887734 0.524 rs722637 chr14:104261723 G/T cg08213375 chr14:104286397 PPP1R13B -0.53 -9.39 -0.45 8.92e-19 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs8073060 0.544 rs225246 chr17:33944773 T/C cg19694781 chr19:47549865 TMEM160 -1.22 -12.66 -0.56 2.1000000000000002e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7824557 0.603 rs2249804 chr8:11215617 C/G cg21775007 chr8:11205619 TDH 0.52 6.2 0.32 1.65e-9 Retinal vascular caliber; LIHC cis rs1707322 0.963 rs12022335 chr1:46402732 C/A cg03146154 chr1:46216737 IPP 0.48 7.74 0.39 1.13e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17784606 chr1:1190558 UBE2J2 0.42 6.07 0.31 3.35e-9 Longevity; LIHC cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg11502198 chr6:26597334 ABT1 0.64 10.05 0.48 5.31e-21 Intelligence (multi-trait analysis); LIHC cis rs4900538 0.855 rs12587464 chr14:102886561 G/C cg18135206 chr14:102964638 TECPR2 -0.71 -10.93 -0.51 4.6e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26933736 chr6:83902998 RWDD2A;PGM3 0.41 6.12 0.31 2.54e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg13152130 chr6:118910203 C6orf204 -0.61 -6.58 -0.34 1.81e-10 Renal cell carcinoma; LIHC cis rs9300255 0.602 rs1727315 chr12:123638930 A/G cg00376283 chr12:123451042 ABCB9 -0.62 -7.04 -0.36 1.04e-11 Neutrophil percentage of white cells; LIHC cis rs56979318 1 rs56979318 chr17:80522718 A/T cg10255544 chr17:80519551 FOXK2 0.49 8.84 0.43 5.32e-17 Reticulocyte count; LIHC trans rs7615952 0.800 rs11915699 chr3:125632684 A/G cg07211511 chr3:129823064 LOC729375 -0.87 -11.05 -0.51 1.83e-24 Blood pressure (smoking interaction); LIHC cis rs9905704 0.647 rs6503888 chr17:57028126 T/C cg05425664 chr17:57184151 TRIM37 -0.44 -6.19 -0.32 1.73e-9 Testicular germ cell tumor; LIHC cis rs2576037 0.583 rs2156049 chr18:44455717 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.88 -0.3 9.96e-9 Personality dimensions; LIHC cis rs2070488 1.000 rs13072809 chr3:38468171 G/A cg24069376 chr3:38537580 EXOG 0.43 7.98 0.4 2.27e-14 Electrocardiographic conduction measures; LIHC cis rs11168351 0.864 rs12228750 chr12:48496997 G/A cg21466736 chr12:48725269 NA 0.63 9.14 0.44 5.64e-18 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs2576037 0.583 rs680018 chr18:44409167 T/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.82 -0.3 1.39e-8 Personality dimensions; LIHC cis rs17401966 1.000 rs35766535 chr1:10284659 T/C cg15208524 chr1:10270712 KIF1B 0.44 6.39 0.33 5.43e-10 Hepatocellular carcinoma; LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg07424592 chr7:64974309 NA 0.44 6.73 0.34 7.36e-11 Calcium levels; LIHC cis rs11671005 0.610 rs8103813 chr19:59072684 C/T cg25952890 chr19:58913133 NA 0.68 6.92 0.35 2.18e-11 Mean platelet volume; LIHC cis rs6840360 0.837 rs13146981 chr4:152720703 T/C cg22705602 chr4:152727874 NA 0.34 7.26 0.37 2.67e-12 Intelligence (multi-trait analysis); LIHC cis rs12765878 1.000 rs10883943 chr10:105651416 G/T cg11005552 chr10:105648138 OBFC1 0.39 6.26 0.32 1.12e-9 Coronary artery disease; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg11905131 chr22:24372483 LOC391322 -0.61 -8.66 -0.42 1.84e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6952808 0.792 rs12531315 chr7:1953650 C/G cg21782813 chr7:2030301 MAD1L1 0.48 8.23 0.41 3.87e-15 Bipolar disorder and schizophrenia; LIHC cis rs12971120 0.891 rs12968731 chr18:72169708 G/T cg25817165 chr18:72167213 CNDP2 -0.71 -12.6 -0.56 3.73e-30 Refractive error; LIHC cis rs7106204 0.748 rs6484032 chr11:24237153 C/A ch.11.24196551F chr11:24239977 NA 0.8 11.43 0.53 7.64e-26 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4689642 0.709 rs4689656 chr4:7225745 A/G cg21353189 chr4:7228343 SORCS2 0.37 6.39 0.33 5.58e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg22963979 chr7:1858916 MAD1L1 0.43 7.33 0.37 1.64e-12 Bipolar disorder and schizophrenia; LIHC cis rs2637030 0.559 rs372006 chr5:52875859 T/A cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.24e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs3741404 0.574 rs616563 chr11:63877501 G/C cg05016508 chr11:63871570 FLRT1;MACROD1 0.42 6.37 0.33 5.95e-10 Platelet count; LIHC trans rs7714584 1.000 rs11950957 chr5:150253914 G/A cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs11167764 1.000 rs7722567 chr5:141483178 C/T cg23435118 chr5:141488016 NDFIP1 -0.44 -6.12 -0.31 2.61e-9 Crohn's disease; LIHC cis rs4969178 0.965 rs2292643 chr17:76395421 G/A cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.01e-12 HDL cholesterol levels; LIHC cis rs11971779 0.680 rs7785903 chr7:139122643 T/C cg07862535 chr7:139043722 LUC7L2 0.59 9.73 0.47 6.52e-20 Diisocyanate-induced asthma; LIHC cis rs8141529 0.732 rs3788409 chr22:29198151 T/G cg02153584 chr22:29168773 CCDC117 0.57 9.28 0.45 1.92e-18 Lymphocyte counts; LIHC cis rs17106184 1.000 rs59128535 chr1:51340401 T/A cg07174182 chr1:51127561 FAF1 -0.62 -6.95 -0.35 1.89e-11 Type 2 diabetes; LIHC cis rs6604026 0.555 rs1415296 chr1:93090476 C/G cg13858687 chr1:93297071 RPL5 -0.61 -5.95 -0.31 6.7e-9 Multiple sclerosis; LIHC cis rs35160687 0.623 rs7569654 chr2:86478022 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.39 6.31 0.32 8.7e-10 Night sleep phenotypes; LIHC cis rs3096299 0.967 rs16965692 chr16:89471482 C/T cg08392591 chr16:89556376 ANKRD11 0.42 6.2 0.32 1.6e-9 Multiple myeloma (IgH translocation); LIHC cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg15691649 chr6:25882328 NA -0.53 -7.65 -0.38 2.07e-13 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04277470 chr13:41707106 KBTBD6 0.41 6.19 0.32 1.69e-9 Cognitive function; LIHC cis rs3106136 0.743 rs6847767 chr4:95276951 C/G cg11021082 chr4:95130006 SMARCAD1 0.39 6.62 0.34 1.41e-10 Capecitabine sensitivity; LIHC cis rs858239 0.601 rs6962526 chr7:23158233 G/A cg23682824 chr7:23144976 KLHL7 0.43 6.46 0.33 3.7e-10 Cerebrospinal fluid biomarker levels; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg05917732 chr6:152623304 SYNE1 0.54 6.59 0.34 1.64e-10 Glycated hemoglobin levels; LIHC cis rs2235642 0.928 rs1057610 chr16:1605537 T/C cg03034668 chr16:1723424 CRAMP1L -0.39 -6.87 -0.35 2.98e-11 Coronary artery disease; LIHC cis rs28830936 0.934 rs4923915 chr15:42119606 C/T cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.08 -0.31 3.26e-9 Diastolic blood pressure; LIHC cis rs9942416 0.592 rs10462521 chr5:74985867 T/C cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs9611565 0.614 rs4822053 chr22:42212936 C/A cg03806693 chr22:41940476 POLR3H -0.71 -8.07 -0.4 1.17e-14 Vitiligo; LIHC cis rs1552244 0.765 rs17050675 chr3:10027686 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.71 9.79 0.47 3.95e-20 Alzheimer's disease; LIHC cis rs6545883 0.965 rs1562308 chr2:61768421 A/C cg14146966 chr2:61757674 XPO1 0.48 8.27 0.41 3.07e-15 Tuberculosis; LIHC cis rs9430161 0.611 rs34032547 chr1:11034374 C/G cg02454025 chr1:11042201 C1orf127 0.96 18.31 0.7 1.11e-52 Ewing sarcoma; LIHC cis rs5769765 0.862 rs7410537 chr22:50317330 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.32 -0.45 1.53e-18 Schizophrenia; LIHC cis rs7959452 0.640 rs11177599 chr12:69721970 G/A cg22834771 chr12:69754056 YEATS4 -0.49 -8.33 -0.41 1.99e-15 Blood protein levels; LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg00800038 chr16:89945340 TCF25 -0.67 -10.78 -0.5 1.64e-23 Skin colour saturation; LIHC trans rs72634258 0.836 rs7545687 chr1:7997183 G/A cg15993354 chr19:12912590 PRDX2 0.51 6.15 0.32 2.11e-9 Inflammatory bowel disease; LIHC cis rs3096299 0.967 rs16965692 chr16:89471482 C/T cg02187348 chr16:89574699 SPG7 0.5 7.41 0.37 1.01e-12 Multiple myeloma (IgH translocation); LIHC trans rs12446632 0.941 rs11640942 chr16:19919946 C/T cg24307341 chr1:21904484 ALPL 0.54 6.08 0.31 3.13e-9 BMI in smokers;BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and physical activity interaction);Body mass index (joint analysis main effects and smoking interaction);Waist circumference;Obesity;Body mass index in physically active individuals;Childhood body mass index;Menarche (age at onset);Body mass index;Hip circumference; LIHC cis rs2108622 0.683 rs6512067 chr19:15982951 G/T cg13772218 chr19:15982569 NA 0.34 7.17 0.36 4.74e-12 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.37 0.45 9.93e-19 Bipolar disorder; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg26709693 chr4:1305780 MAEA 0.41 6.19 0.32 1.72e-9 Longevity; LIHC cis rs1018836 0.628 rs35816262 chr8:91511017 C/G cg16814680 chr8:91681699 NA -0.47 -7.65 -0.38 2.01e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 0.42 5.91 0.3 8.15e-9 Colorectal cancer; LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg00280220 chr17:61926910 NA 0.42 6.83 0.35 3.97e-11 Prudent dietary pattern; LIHC cis rs8078723 0.705 rs8065443 chr17:38208940 A/G cg17467752 chr17:38218738 THRA -0.84 -16.47 -0.67 2.7e-45 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg07424592 chr7:64974309 NA 0.84 9.64 0.46 1.3e-19 Diabetic kidney disease; LIHC cis rs6690583 0.623 rs55721024 chr1:85454447 A/C cg22153463 chr1:85462885 MCOLN2 0.5 6.03 0.31 4.19e-9 Serum sulfate level; LIHC cis rs2295359 0.724 rs10489630 chr1:67662622 G/T cg12940439 chr1:67600707 NA -0.35 -6.17 -0.32 1.94e-9 Psoriasis; LIHC cis rs739401 0.611 rs7130841 chr11:3043658 A/G cg08508325 chr11:3079039 CARS -0.32 -6.97 -0.35 1.66e-11 Longevity; LIHC cis rs9733 0.519 rs7511673 chr1:150707636 A/T cg17724175 chr1:150552817 MCL1 0.49 9.89 0.47 1.92e-20 Tonsillectomy; LIHC cis rs1005277 0.502 rs2800484 chr10:38542415 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.37 -0.33 5.99e-10 Extrinsic epigenetic age acceleration; LIHC cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg19626725 chr5:178986131 RUFY1 -0.39 -6.07 -0.31 3.43e-9 Lung cancer; LIHC cis rs9303401 0.659 rs8074016 chr17:56840587 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.49 0.59 1.48e-33 Cognitive test performance; LIHC cis rs12611088 0.602 rs2599455 chr19:44025235 T/A cg13740135 chr19:44006432 PHLDB3 -0.41 -6.03 -0.31 4.21e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs17685 0.558 rs60787921 chr7:75792844 C/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.33 -0.32 7.51e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2304069 0.909 rs8073 chr5:149362400 T/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.92 -11.65 -0.53 1.17e-26 HIV-1 control; LIHC cis rs7552404 0.765 rs1251078 chr1:76189488 C/G cg22875332 chr1:76189707 ACADM -0.56 -12.18 -0.55 1.37e-28 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9916302 0.851 rs6503502 chr17:37501855 A/G cg00129232 chr17:37814104 STARD3 0.38 6.15 0.32 2.21e-9 Glomerular filtration rate (creatinine); LIHC cis rs7572733 0.534 rs700678 chr2:198705820 T/C cg10820045 chr2:198174542 NA 0.47 7.1 0.36 7.21e-12 Dermatomyositis; LIHC trans rs116095464 0.558 rs73024831 chr5:257192 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs12701220 0.655 rs7784403 chr7:1153077 G/A cg26769984 chr7:1090371 C7orf50 0.49 6.03 0.31 4.23e-9 Bronchopulmonary dysplasia; LIHC cis rs3853824 0.965 rs4793834 chr17:54903662 C/T cg13675837 chr17:54910204 DGKE 0.41 5.9 0.3 8.85e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg26338869 chr17:61819248 STRADA 0.53 7.15 0.36 5.36e-12 Height; LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg02782426 chr3:40428986 ENTPD3 0.34 6.27 0.32 1.08e-9 Renal cell carcinoma; LIHC trans rs11098499 0.909 rs7659501 chr4:120371552 G/T cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs8060686 0.545 rs12444188 chr16:68282077 G/A cg05110241 chr16:68378359 PRMT7 -0.62 -7.07 -0.36 9e-12 HDL cholesterol;Metabolic syndrome; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg04413644 chr1:9242184 NA 0.41 6.14 0.32 2.27e-9 Migraine with aura; LIHC cis rs9517320 1.000 rs912337 chr13:99141272 A/G cg07423050 chr13:99094983 FARP1 -0.36 -5.96 -0.31 6.24e-9 Longevity; LIHC cis rs7618501 0.516 rs2856236 chr3:50161717 A/C cg21467203 chr3:49911342 NA 0.42 7.39 0.37 1.14e-12 Intelligence (multi-trait analysis); LIHC cis rs1557765 0.527 rs10832782 chr11:17397273 G/C cg15432903 chr11:17409602 KCNJ11 0.43 6.57 0.33 1.93e-10 Body mass index;Social communication problems; LIHC cis rs7945705 0.870 rs1109305 chr11:8955272 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.39 6.6 0.34 1.61e-10 Hemoglobin concentration; LIHC cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg03517284 chr6:25882590 NA -0.63 -8.86 -0.43 4.45e-17 Blood metabolite levels; LIHC cis rs921968 0.542 rs630858 chr2:219409689 C/A cg02176678 chr2:219576539 TTLL4 0.51 7.09 0.36 7.53e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs1707322 1.000 rs1707303 chr1:46598273 A/C cg03146154 chr1:46216737 IPP -0.45 -7.12 -0.36 6.42e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs146671954 1 rs146671954 chr9:136934203 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.58 -6.49 -0.33 3.06e-10 Red cell distribution width; LIHC cis rs7618501 0.635 rs7635002 chr3:49989155 T/G cg24110177 chr3:50126178 RBM5 -0.47 -7.31 -0.37 1.86e-12 Intelligence (multi-trait analysis); LIHC cis rs831571 0.774 rs254858 chr3:64056255 G/T cg16258503 chr3:63850278 ATXN7;THOC7 0.46 5.84 0.3 1.2e-8 Type 2 diabetes; LIHC cis rs9611565 0.559 rs6002408 chr22:41967870 C/T cg03806693 chr22:41940476 POLR3H -0.87 -9.68 -0.46 9.74e-20 Vitiligo; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.91 0.57 2.57e-31 Prudent dietary pattern; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg01032570 chr8:22224534 SLC39A14 -0.5 -6.06 -0.31 3.52e-9 Preeclampsia; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.73 10.65 0.5 4.77e-23 Lymphocyte counts; LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg00800038 chr16:89945340 TCF25 -0.66 -10.35 -0.49 5.25e-22 Skin colour saturation; LIHC cis rs9303401 0.538 rs35454383 chr17:56475599 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.87 10.89 0.51 6.48e-24 Cognitive test performance; LIHC cis rs9911578 1.000 rs654778 chr17:56736473 A/C cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.666 rs4074231 chr11:978219 G/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs17376456 0.569 rs6556839 chr5:93206292 T/C cg25358565 chr5:93447407 FAM172A -0.8 -7.7 -0.38 1.47e-13 Diabetic retinopathy; LIHC cis rs72781680 0.848 rs55725028 chr2:23966447 A/G cg08917208 chr2:24149416 ATAD2B 0.95 8.12 0.4 8.61e-15 Lymphocyte counts; LIHC cis rs2439831 0.850 rs68079546 chr15:44136957 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.33 0.41 2.02e-15 Lung cancer in ever smokers; LIHC cis rs12971120 1.000 rs3829640 chr18:72174980 A/G cg26446133 chr18:72167187 CNDP2 -0.79 -15.05 -0.63 1.24e-39 Refractive error; LIHC cis rs10751667 0.643 rs7396407 chr11:929374 A/T ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC trans rs8113308 0.810 rs8100541 chr19:52449695 A/G cg14959425 chr7:20447707 ITGB8 -0.47 -6.11 -0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs3823572 0.542 rs11764961 chr7:133631142 C/A cg03336402 chr7:133662267 EXOC4 0.47 5.84 0.3 1.22e-8 Intelligence (multi-trait analysis); LIHC cis rs7683537 0.501 rs2171838 chr4:185667404 A/G cg04058563 chr4:185651563 MLF1IP -0.59 -6.21 -0.32 1.53e-9 Systemic lupus erythematosus; LIHC cis rs2243480 0.708 rs35825036 chr7:65986502 T/C cg12463550 chr7:65579703 CRCP 0.67 6.9 0.35 2.49e-11 Diabetic kidney disease; LIHC cis rs68170813 0.559 rs17429118 chr7:106964052 C/T cg02696742 chr7:106810147 HBP1 -0.5 -5.72 -0.3 2.38e-8 Coronary artery disease; LIHC cis rs11105298 0.891 rs11105314 chr12:89924559 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.61 -6.9 -0.35 2.47e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7582720 1.000 rs6723704 chr2:203738664 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17216904 chr3:57262489 APPL1 0.49 7.14 0.36 5.55e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs9354352 0.935 rs7766730 chr6:66697003 C/A cg07460842 chr6:66804631 NA 0.58 9.28 0.45 1.95e-18 Initial pursuit acceleration in psychotic disorders; LIHC cis rs7617480 0.585 rs7373072 chr3:48960017 T/A cg07636037 chr3:49044803 WDR6 0.77 9.9 0.47 1.72e-20 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs950169 0.881 rs34591918 chr15:84950833 C/T cg17507749 chr15:85114479 UBE2QP1 0.74 8.69 0.43 1.55e-16 Schizophrenia; LIHC cis rs12022452 0.591 rs61781641 chr1:40983084 G/T cg25568243 chr1:40974465 DEM1 0.46 6.17 0.32 1.91e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs11758351 1.000 rs76722536 chr6:26192946 C/G cg03854865 chr6:26224070 HIST1H3E 0.65 7.31 0.37 1.96e-12 Gout;Renal underexcretion gout; LIHC cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.5 0.56 8.64e-30 Alzheimer's disease; LIHC cis rs986417 1.000 rs1018531 chr14:60970844 C/T cg27398547 chr14:60952738 C14orf39 0.85 9.85 0.47 2.61e-20 Gut microbiota (bacterial taxa); LIHC cis rs7131987 0.903 rs67517901 chr12:29421346 A/G cg00204748 chr12:29376779 FAR2 0.42 7.83 0.39 6.32e-14 QT interval; LIHC cis rs9611565 0.694 rs5758411 chr22:42079734 G/A cg06634786 chr22:41940651 POLR3H 0.55 5.99 0.31 5.39e-9 Vitiligo; LIHC cis rs72781680 0.898 rs72786288 chr2:24075416 G/T cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs35110281 0.667 rs2155722 chr21:45096206 A/G cg21573476 chr21:45109991 RRP1B 0.57 11.14 0.52 8.29e-25 Mean corpuscular volume; LIHC cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg09913183 chr17:42254507 C17orf65;ASB16 0.69 10.84 0.51 9.52e-24 Total body bone mineral density; LIHC cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 11.32 0.52 1.84e-25 Platelet count; LIHC cis rs1639906 0.507 rs1004643 chr7:2185324 G/C cg04267008 chr7:1944627 MAD1L1 0.5 6.73 0.34 7.34e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs7582180 0.629 rs2309798 chr2:100956949 G/A cg14675211 chr2:100938903 LONRF2 0.54 8.72 0.43 1.2e-16 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg23978390 chr7:1156363 C7orf50 0.63 9.81 0.47 3.55e-20 Longevity;Endometriosis; LIHC cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg08888203 chr3:10149979 C3orf24 -0.63 -7.22 -0.36 3.43e-12 Alzheimer's disease; LIHC cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg02290350 chr8:58132656 NA 0.4 8.44 0.42 9.38e-16 Developmental language disorder (linguistic errors); LIHC cis rs965469 1.000 rs6037583 chr20:3360632 G/A cg25506879 chr20:3388711 C20orf194 -0.54 -6.4 -0.33 4.98e-10 IFN-related cytopenia; LIHC cis rs7618501 1.000 rs60205400 chr3:49800272 C/T cg21467203 chr3:49911342 NA -0.41 -7.07 -0.36 9e-12 Intelligence (multi-trait analysis); LIHC cis rs2073300 1.000 rs6132625 chr20:23444671 C/T cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs769267 0.895 rs2965189 chr19:19519518 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.89 0.39 4.21e-14 Tonsillectomy; LIHC cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg24675658 chr1:53192096 ZYG11B 0.57 8.95 0.44 2.24e-17 Monocyte count; LIHC cis rs8084351 0.577 rs4078161 chr18:50609919 G/T cg24270629 chr18:50823537 DCC 0.44 6.73 0.34 7.36e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg00091569 chr3:40428383 ENTPD3 0.4 6.83 0.35 4.01e-11 Renal cell carcinoma; LIHC cis rs6582630 0.555 rs7965311 chr12:38513307 G/A cg13010199 chr12:38710504 ALG10B -0.45 -6.39 -0.33 5.32e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs9790314 0.502 rs7647118 chr3:161016165 T/C cg03342759 chr3:160939853 NMD3 -0.66 -9.92 -0.47 1.55e-20 Morning vs. evening chronotype; LIHC cis rs1577917 0.958 rs11755048 chr6:86514334 A/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.24 -0.36 3.02e-12 Response to antipsychotic treatment; LIHC cis rs950169 0.800 rs34302901 chr15:85110943 C/G cg03959625 chr15:84868606 LOC388152 0.42 5.79 0.3 1.63e-8 Schizophrenia; LIHC cis rs778371 0.697 rs2344613 chr2:233603065 C/G cg08000102 chr2:233561755 GIGYF2 0.77 9.41 0.45 7.41e-19 Schizophrenia; LIHC cis rs1577917 1.000 rs6936048 chr6:86702608 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.63 -0.46 1.43e-19 Response to antipsychotic treatment; LIHC cis rs34779708 0.966 rs11010102 chr10:35411066 T/A cg04310649 chr10:35416472 CREM -0.45 -6.08 -0.31 3.17e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1005277 0.557 rs2983338 chr10:38550734 C/T cg17219203 chr10:38645113 HSD17B7P2 -0.39 -5.72 -0.3 2.3e-8 Extrinsic epigenetic age acceleration; LIHC cis rs9868809 0.505 rs9877685 chr3:48748588 C/T cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.6e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs6762477 0.748 rs3755831 chr3:50228767 G/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.49 -7.59 -0.38 3.01e-13 Menarche (age at onset); LIHC cis rs709400 0.628 rs12879085 chr14:103874420 G/A cg26031613 chr14:104095156 KLC1 -0.72 -9.53 -0.46 2.97e-19 Body mass index; LIHC cis rs894734 0.535 rs2366142 chr12:54323148 T/C cg25024717 chr12:54324583 NA -0.38 -8.15 -0.4 6.74e-15 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs1691799 0.867 rs1168330 chr12:66763167 C/T cg16791601 chr12:66731901 HELB 0.48 10.1 0.48 3.8e-21 White blood cell count (basophil); LIHC cis rs875971 0.545 rs11766183 chr7:65839160 G/C cg11764359 chr7:65958608 NA 0.6 8.43 0.41 1.01e-15 Aortic root size; LIHC cis rs529866 0.500 rs918739 chr16:11439733 G/T cg00044050 chr16:11439710 C16orf75 -0.44 -6.1 -0.31 2.95e-9 Crohn's disease;Inflammatory bowel disease; LIHC cis rs3099143 1.000 rs7174048 chr15:77165416 T/C cg21673338 chr15:77095150 SCAPER 0.49 7.71 0.38 1.42e-13 Recalcitrant atopic dermatitis; LIHC cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg06481639 chr22:41940642 POLR3H -0.69 -6.83 -0.35 3.82e-11 Vitiligo; LIHC cis rs9916302 0.904 rs8070695 chr17:37478062 C/T cg03013999 chr17:37608204 MED1 -0.34 -5.91 -0.3 8.27e-9 Glomerular filtration rate (creatinine); LIHC cis rs870825 0.929 rs72689260 chr4:185590656 G/T cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs2795502 1.000 rs2795508 chr10:43353555 G/T cg20628663 chr10:43360327 NA 0.49 7.79 0.39 8.07e-14 Blood protein levels; LIHC cis rs35883536 0.967 rs1055044 chr1:101171354 A/G cg14515779 chr1:101123966 NA -0.66 -12.58 -0.56 4.52e-30 Monocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06747863 chr12:118810789 TAOK3 0.4 6.21 0.32 1.51e-9 Pancreatic cancer; LIHC cis rs6867032 0.958 rs4975797 chr5:2015573 G/A cg26168224 chr5:2018326 NA 0.31 7.71 0.38 1.36e-13 Gut microbiome composition (winter); LIHC cis rs8044995 0.563 rs7500163 chr16:68364358 C/G cg09835421 chr16:68378352 PRMT7 -0.86 -10.1 -0.48 3.72e-21 Schizophrenia; LIHC cis rs10426930 0.752 rs10401934 chr19:5038715 C/T cg18473234 chr19:5097819 KDM4B 0.56 6.38 0.33 5.87e-10 Monocyte percentage of white cells; LIHC cis rs700651 0.789 rs882954 chr2:198907444 A/G cg03934865 chr2:198174659 NA 0.47 6.62 0.34 1.42e-10 Intracranial aneurysm; LIHC cis rs2832191 0.720 rs2832194 chr21:30494250 T/C cg08807101 chr21:30365312 RNF160 -0.57 -8.96 -0.44 2.14e-17 Dental caries; LIHC cis rs1552244 0.882 rs9757159 chr3:10039166 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs918629 0.724 rs3734131 chr5:95278679 G/A cg10483112 chr5:95245456 ELL2 -0.36 -6.1 -0.31 2.87e-9 IgG glycosylation; LIHC cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg17554472 chr22:41940697 POLR3H -0.53 -5.82 -0.3 1.35e-8 Vitiligo; LIHC cis rs1801251 1.000 rs2100053 chr2:233719516 G/T cg25237894 chr2:233734115 C2orf82 -0.58 -11.38 -0.52 1.17e-25 Coronary artery disease; LIHC cis rs11122272 0.735 rs2491412 chr1:231535880 A/T cg06096015 chr1:231504339 EGLN1 0.49 9.37 0.45 9.83e-19 Hemoglobin concentration; LIHC cis rs10463316 0.894 rs7708499 chr5:150765906 A/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.04e-10 Metabolite levels (Pyroglutamine); LIHC cis rs875971 0.798 rs7789615 chr7:65878661 A/G cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC cis rs11971779 0.616 rs6974907 chr7:139068729 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2235642 0.653 rs7197288 chr16:1654753 C/A cg09025071 chr16:1593152 IFT140;TMEM204 0.3 5.83 0.3 1.28e-8 Coronary artery disease; LIHC cis rs12644436 0.628 rs1381961 chr4:88802458 C/G cg06891869 chr4:88767617 MEPE 0.42 7.38 0.37 1.22e-12 HIV-1 viral setpoint; LIHC cis rs365132 0.875 rs2456178 chr5:176413570 C/G cg16309518 chr5:176445507 NA -0.58 -11.56 -0.53 2.58e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs11031096 0.782 rs7130580 chr11:4169301 G/A cg18678763 chr11:4115507 RRM1 -0.53 -8.11 -0.4 8.95e-15 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg13012494 chr21:47604986 C21orf56 0.37 5.8 0.3 1.55e-8 Testicular germ cell tumor; LIHC cis rs67311347 0.577 rs11129870 chr3:40260406 G/A cg13409248 chr3:40428643 ENTPD3 0.41 6.41 0.33 4.79e-10 Renal cell carcinoma; LIHC cis rs10423674 0.526 rs11668545 chr19:18829529 C/T cg12034943 chr19:18811790 CRTC1 -0.37 -5.85 -0.3 1.14e-8 Menarche (age at onset); LIHC cis rs6089584 0.527 rs927589 chr20:60606363 A/G cg06108461 chr20:60628389 TAF4 -0.65 -9.2 -0.45 3.65e-18 Body mass index; LIHC cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg11062466 chr8:58055876 NA 0.47 6.41 0.33 4.89e-10 Developmental language disorder (linguistic errors); LIHC cis rs963731 0.677 rs297122 chr2:39309141 T/C cg04010122 chr2:39346883 SOS1 -0.71 -5.76 -0.3 1.86e-8 Corticobasal degeneration; LIHC cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.52 0.49 1.29e-22 Total body bone mineral density; LIHC cis rs941873 0.805 rs10762860 chr10:81117794 C/G cg09469691 chr10:81107165 PPIF 0.68 10.3 0.49 7.56e-22 Height; LIHC cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg13395646 chr4:1353034 KIAA1530 0.41 6.44 0.33 4.1e-10 Obesity-related traits; LIHC cis rs2354432 0.505 rs3737845 chr1:146724408 A/G cg25205988 chr1:146714368 CHD1L 0.89 10.3 0.49 7.5e-22 Mitochondrial DNA levels; LIHC cis rs10080237 0.564 rs2490224 chr6:80809833 G/A cg08355045 chr6:80787529 NA 0.35 7.1 0.36 7.41e-12 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals; LIHC cis rs2952156 0.959 rs907087 chr17:37828787 G/A cg00129232 chr17:37814104 STARD3 -0.49 -9.12 -0.44 6.66e-18 Asthma; LIHC cis rs4148883 0.689 rs1869458 chr4:100024728 C/G cg12011299 chr4:100065546 ADH4 0.37 7.51 0.38 5.24e-13 Alcohol dependence; LIHC cis rs748404 0.604 rs2278857 chr15:43632549 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.57 10.33 0.49 6.03e-22 Lung cancer; LIHC cis rs7613875 0.600 rs1061474 chr3:50144951 T/C cg24110177 chr3:50126178 RBM5 0.58 9.63 0.46 1.45e-19 Body mass index; LIHC cis rs4788570 0.584 rs9934301 chr16:71756845 C/G cg06353428 chr16:71660113 MARVELD3 1.35 13.66 0.59 3.43e-34 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.579 rs1780145 chr10:38537070 A/G cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.81 -0.3 1.42e-8 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg07308232 chr7:1071921 C7orf50 -0.55 -8.99 -0.44 1.76e-17 Longevity;Endometriosis; LIHC cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg05590025 chr7:65112418 INTS4L2 -0.68 -7.63 -0.38 2.29e-13 Diabetic kidney disease; LIHC cis rs6598955 0.670 rs7531518 chr1:26539749 T/C cg04990556 chr1:26633338 UBXN11 -0.56 -9.09 -0.44 8.38e-18 Obesity-related traits; LIHC cis rs919433 0.617 rs4850807 chr2:198575975 G/A cg00792783 chr2:198669748 PLCL1 -0.44 -6.43 -0.33 4.2e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2153535 0.601 rs2143353 chr6:8530111 T/G cg23788917 chr6:8435910 SLC35B3 0.64 9.08 0.44 8.77e-18 Motion sickness; LIHC cis rs12477438 0.572 rs10170063 chr2:99655639 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs8062405 1.000 rs8055138 chr16:28891465 C/T cg00204512 chr16:28754710 NA 0.34 6.26 0.32 1.15e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs1814175 0.645 rs28447324 chr11:50046629 C/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs12477438 1.000 rs6732980 chr2:99921613 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -8.5 -0.42 6.15e-16 Chronic sinus infection; LIHC cis rs4654899 0.758 rs6426667 chr1:21396216 C/A cg08539965 chr1:21396338 EIF4G3 0.33 5.8 0.3 1.49e-8 Superior frontal gyrus grey matter volume; LIHC cis rs2236918 0.932 rs1776178 chr1:242011534 C/T cg17736920 chr1:242011382 EXO1 -0.54 -7.87 -0.39 4.7e-14 Menopause (age at onset); LIHC cis rs9905704 0.647 rs6503892 chr17:57067086 G/A cg12560992 chr17:57184187 TRIM37 0.67 9.91 0.47 1.64e-20 Testicular germ cell tumor; LIHC cis rs919433 0.854 rs787994 chr2:198223121 T/C cg10820045 chr2:198174542 NA 0.53 8.62 0.42 2.58e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8180040 0.729 rs11720439 chr3:47347003 T/G cg27129171 chr3:47204927 SETD2 -0.5 -8.01 -0.4 1.77e-14 Colorectal cancer; LIHC cis rs1023500 0.596 rs5751209 chr22:42451603 A/G cg04733989 chr22:42467013 NAGA 0.66 9.36 0.45 1.09e-18 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11095277 chr14:50151270 POLE2 0.46 6.44 0.33 4.02e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6963495 0.818 rs6956249 chr7:105149743 A/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs3749237 0.595 rs1050088 chr3:49570882 C/T cg07636037 chr3:49044803 WDR6 -0.53 -7.96 -0.4 2.54e-14 Resting heart rate; LIHC cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg05896524 chr21:47604654 C21orf56 0.46 6.85 0.35 3.4e-11 Testicular germ cell tumor; LIHC cis rs1008375 1.000 rs10019856 chr4:17615742 T/A cg16339924 chr4:17578868 LAP3 0.44 6.08 0.31 3.2e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4727027 0.901 rs11760293 chr7:148811725 A/G cg23583168 chr7:148888333 NA -0.7 -9.73 -0.47 6.44e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6426558 0.537 rs1320494 chr1:227241300 A/T cg10327440 chr1:227177885 CDC42BPA 0.44 6.75 0.34 6.53e-11 Neutrophil percentage of white cells; LIHC cis rs12986413 0.967 rs4807211 chr19:2174643 G/A cg09261902 chr19:2140048 AP3D1 0.37 6.38 0.33 5.85e-10 Height; LIHC cis rs6840360 1.000 rs3792691 chr4:152635803 C/T cg22705602 chr4:152727874 NA 0.32 6.86 0.35 3.16e-11 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.659 rs34382037 chr17:56643550 G/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs9811920 0.609 rs10936005 chr3:99674093 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.87 -0.3 1.01e-8 Axial length; LIHC cis rs6788895 1.000 rs73010967 chr3:150498056 T/C cg07663535 chr3:150480033 SIAH2 0.55 6.97 0.35 1.69e-11 Breast cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19149222 chr2:74682139 INO80B 0.39 6.66 0.34 1.06e-10 Calcium levels; LIHC cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg11764359 chr7:65958608 NA 0.55 6.53 0.33 2.35e-10 Diabetic kidney disease; LIHC cis rs4665809 0.759 rs62128394 chr2:26364026 T/G cg04944784 chr2:26401820 FAM59B 0.68 7.33 0.37 1.69e-12 Gut microbiome composition (summer); LIHC cis rs769267 0.965 rs2017964 chr19:19387149 T/C cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg21171335 chr12:122356390 WDR66 0.53 8.09 0.4 1.08e-14 Mean corpuscular volume; LIHC cis rs4268898 0.516 rs7597149 chr2:24371962 C/T cg06627628 chr2:24431161 ITSN2 0.48 7.05 0.36 9.83e-12 Asthma; LIHC cis rs7116495 0.867 rs506395 chr11:71577953 A/G cg26138937 chr11:71823887 C11orf51 0.69 6.83 0.35 3.91e-11 Severe influenza A (H1N1) infection; LIHC cis rs2795502 1.000 rs2744092 chr10:43339343 T/C cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs400736 0.576 rs10864328 chr1:8164456 G/C cg25007680 chr1:8021821 PARK7 -0.48 -7.22 -0.36 3.31e-12 Response to antidepressants and depression; LIHC cis rs875971 0.895 rs10447522 chr7:65796074 A/G cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.27 0.41 3.07e-15 Platelet count; LIHC cis rs2153535 0.526 rs1796689 chr6:8536433 A/C cg21535247 chr6:8435926 SLC35B3 0.63 8.12 0.4 8.83e-15 Motion sickness; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs1144333 0.655 rs12402347 chr1:76447986 C/T cg22875332 chr1:76189707 ACADM 0.41 6.01 0.31 4.79e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs11039100 0.850 rs11039168 chr11:5844723 C/A cg11650987 chr12:10280440 CLEC7A 0.42 6.19 0.32 1.77e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10751667 1.000 rs4074232 chr11:977682 C/G cg10932868 chr11:921992 NA 0.36 6.77 0.34 5.46e-11 Alzheimer's disease (late onset); LIHC cis rs7116495 0.609 rs2852365 chr11:71715218 T/C cg26138937 chr11:71823887 C11orf51 -1.32 -10.9 -0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs11673344 0.832 rs77772684 chr19:37546740 C/G cg27390819 chr19:37464633 NA -0.51 -6.13 -0.31 2.38e-9 Obesity-related traits; LIHC cis rs1580019 0.713 rs2122632 chr7:32524686 A/G cg06627557 chr7:32535165 LSM5;AVL9 -1.06 -22.02 -0.77 1.48e-67 Cognitive ability; LIHC cis rs12893668 0.703 rs34186780 chr14:104027595 T/G cg19000871 chr14:103996768 TRMT61A -0.43 -7.17 -0.36 4.59e-12 Reticulocyte count; LIHC cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg18230493 chr5:56204884 C5orf35 -0.46 -6.48 -0.33 3.24e-10 Initial pursuit acceleration; LIHC cis rs35110281 0.782 rs2246602 chr21:45064296 C/A cg01579765 chr21:45077557 HSF2BP -0.33 -6.16 -0.32 1.99e-9 Mean corpuscular volume; LIHC cis rs12477438 0.798 rs6740035 chr2:99576578 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.95 -0.47 1.22e-20 Chronic sinus infection; LIHC cis rs17253792 0.732 rs75796044 chr14:56034128 C/T cg24579896 chr14:56047964 C14orf33;KTN1 0.73 6.03 0.31 4.36e-9 Putamen volume; LIHC cis rs743757 1.000 rs2073496 chr3:50431142 A/G cg05260129 chr3:50388622 TUSC4;CYB561D2 0.47 6.74 0.34 6.8e-11 Diastolic blood pressure; LIHC cis rs79149102 0.579 rs28394281 chr15:75326754 C/G cg17294928 chr15:75287854 SCAMP5 -0.48 -6.19 -0.32 1.71e-9 Lung cancer; LIHC cis rs807669 0.934 rs1780643 chr22:19191725 T/C cg02655711 chr22:19163373 SLC25A1 0.7 10.62 0.5 5.74e-23 Metabolite levels; LIHC cis rs4820294 0.961 rs62236664 chr22:38059427 T/C cg00142150 chr22:38071001 LGALS1 0.7 11.36 0.52 1.36e-25 Fat distribution (HIV); LIHC cis rs1215050 0.791 rs2123100 chr4:98803747 T/C cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.86e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2455799 0.613 rs2455813 chr3:15735051 C/G cg16303742 chr3:15540471 COLQ -0.34 -5.83 -0.3 1.28e-8 Mean platelet volume; LIHC cis rs1023500 0.573 rs133377 chr22:42466950 C/T cg00645731 chr22:42541494 CYP2D7P1 0.38 5.98 0.31 5.47e-9 Schizophrenia; LIHC cis rs6912958 0.712 rs2814712 chr6:88396322 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.44 7.64 0.38 2.17e-13 Monocyte percentage of white cells; LIHC cis rs7512552 0.809 rs698923 chr1:150379159 G/A cg15654264 chr1:150340011 RPRD2 0.69 11.33 0.52 1.78e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9921222 0.597 rs7193109 chr16:413523 T/G cg00101154 chr16:420108 MRPL28 -0.59 -8.9 -0.43 3.38e-17 Bone mineral density (spine);Bone mineral density; LIHC cis rs17685 0.753 rs6951808 chr7:75772413 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4803468 1.000 rs11670757 chr19:41913431 G/T cg09537434 chr19:41945824 ATP5SL -1.02 -21.2 -0.75 2.88e-64 Height; LIHC cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs10744422 1.000 rs4759381 chr12:123348480 G/A cg18912006 chr12:123335444 HIP1R -0.68 -8.05 -0.4 1.37e-14 Schizophrenia; LIHC cis rs4819052 0.819 rs7279136 chr21:46692287 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 11.87 0.54 1.88e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19935506 chr2:242626874 DTYMK 0.38 6.26 0.32 1.15e-9 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04640194 chr12:56754023 STAT2 0.48 7.0 0.35 1.38e-11 Pancreatic cancer; LIHC trans rs61931739 0.534 rs11053010 chr12:34093228 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.83 0.35 3.89e-11 Morning vs. evening chronotype; LIHC cis rs11673344 0.800 rs826323 chr19:37504953 G/A cg27390819 chr19:37464633 NA -0.5 -6.2 -0.32 1.66e-9 Obesity-related traits; LIHC cis rs3806843 1.000 rs3733707 chr5:140181892 T/C cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.61e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7959452 0.590 rs10878974 chr12:69781528 C/G cg20891283 chr12:69753455 YEATS4 0.9 19.55 0.73 1.18e-57 Blood protein levels; LIHC cis rs7264396 0.563 rs6060567 chr20:34288250 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.5 -0.42 6.02e-16 Total cholesterol levels; LIHC cis rs16866061 1.000 rs11688397 chr2:225393173 C/T cg12698349 chr2:225449008 CUL3 0.8 14.01 0.6 1.44e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs10916814 0.546 rs10799644 chr1:20903195 G/T cg24502330 chr1:20914028 CDA -0.3 -6.6 -0.34 1.55e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7408868 0.764 rs45504393 chr19:15277010 A/G cg09752223 chr19:15281200 NOTCH3 -0.37 -5.86 -0.3 1.07e-8 Pulse pressure; LIHC cis rs6456156 0.586 rs2345753 chr6:167484344 T/A cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.07e-9 Primary biliary cholangitis; LIHC cis rs2380220 0.808 rs2263180 chr6:95902309 G/A cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg10755058 chr3:40428713 ENTPD3 -0.42 -7.25 -0.36 2.8e-12 Renal cell carcinoma; LIHC cis rs13191362 1.000 rs34192365 chr6:163012382 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.77 0.3 1.82e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg26229092 chr10:31816809 ZEB1 -0.3 -7.28 -0.37 2.35e-12 Calcium levels; LIHC cis rs2404602 0.684 rs2454451 chr15:76861461 G/T cg23625390 chr15:77176239 SCAPER 0.54 8.96 0.44 2.14e-17 Blood metabolite levels; LIHC cis rs2274273 0.805 rs8012156 chr14:55552500 G/T cg01864836 chr14:55583639 NA -0.36 -6.2 -0.32 1.65e-9 Protein biomarker; LIHC cis rs9457247 0.967 rs1187532 chr6:167382020 G/A cg23791538 chr6:167370224 RNASET2 -0.67 -11.63 -0.53 1.44e-26 Crohn's disease; LIHC cis rs208520 0.507 rs7755710 chr6:66783355 G/A cg07460842 chr6:66804631 NA -1.02 -19.22 -0.72 2.33e-56 Exhaled nitric oxide output; LIHC cis rs6691722 0.503 rs2274167 chr1:24707296 C/T cg18323236 chr1:24743029 NIPAL3 0.41 7.44 0.37 8.21e-13 Response to interferon beta in multiple sclerosis; LIHC cis rs4934494 0.727 rs3824607 chr10:91471015 A/G cg19698084 chr10:91461284 KIF20B -0.47 -6.35 -0.32 6.84e-10 Red blood cell count; LIHC cis rs1707322 0.752 rs11211145 chr1:46108491 A/C cg03146154 chr1:46216737 IPP 0.53 8.41 0.41 1.16e-15 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6570726 0.967 rs450973 chr6:145863065 C/A cg23711669 chr6:146136114 FBXO30 0.51 8.81 0.43 6.64e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs2760061 0.626 rs2796057 chr1:228124414 G/C cg02753203 chr1:228287806 NA -0.47 -7.56 -0.38 3.74e-13 Diastolic blood pressure; LIHC cis rs4803455 0.565 rs11670143 chr19:41864971 A/G cg08477640 chr19:41863820 B9D2 0.33 5.87 0.3 1.01e-8 Migraine;Coronary artery disease; LIHC cis rs5769765 1.000 rs5770741 chr22:50270215 A/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs903552 0.866 rs11247296 chr15:102007919 T/C cg19295451 chr15:102010161 PCSK6 -0.53 -7.51 -0.38 5.04e-13 Diabetic kidney disease; LIHC cis rs7191439 0.858 rs4238685 chr16:88775220 T/C cg27087555 chr16:88793112 FAM38A -1.44 -10.74 -0.5 2.14e-23 Plateletcrit; LIHC cis rs9916302 0.861 rs10491129 chr17:37461643 T/G cg03013999 chr17:37608204 MED1 -0.36 -6.01 -0.31 4.76e-9 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg08280861 chr8:58055591 NA 0.56 6.2 0.32 1.61e-9 Developmental language disorder (linguistic errors); LIHC cis rs225245 0.791 rs7216391 chr17:34024706 G/A cg05299278 chr17:33885742 SLFN14 0.23 6.2 0.32 1.65e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg12310025 chr6:25882481 NA 0.6 8.55 0.42 4.08e-16 Blood metabolite levels; LIHC cis rs35110281 0.627 rs6518268 chr21:44967448 A/G cg04455712 chr21:45112962 RRP1B 0.4 6.69 0.34 9.14e-11 Mean corpuscular volume; LIHC cis rs2050392 0.544 rs598672 chr10:30742388 C/T cg25182066 chr10:30743637 MAP3K8 -0.7 -11.06 -0.51 1.61e-24 Inflammatory bowel disease; LIHC cis rs11098499 1.000 rs13435802 chr4:120177960 A/T cg09307838 chr4:120376055 NA -0.75 -10.96 -0.51 3.76e-24 Corneal astigmatism; LIHC trans rs11153056 0.538 rs9386626 chr6:107543195 G/A cg12119218 chr10:70287206 SLC25A16 -0.44 -6.17 -0.32 1.88e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg18252515 chr7:66147081 NA 1.29 17.4 0.69 4.95e-49 Diabetic kidney disease; LIHC cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg12756686 chr19:29218302 NA 0.44 6.83 0.35 3.94e-11 Methadone dose in opioid dependence; LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg04352962 chr1:209979756 IRF6 0.38 5.9 0.3 8.81e-9 Cleft lip with or without cleft palate; LIHC trans rs12478296 0.792 rs6755390 chr2:243012998 C/T cg01596870 chr19:55963115 NA -0.65 -8.58 -0.42 3.29e-16 Obesity-related traits; LIHC cis rs79057730 0.599 rs6944167 chr7:826274 G/C cg11064039 chr7:766100 PRKAR1B;HEATR2 0.8 9.08 0.44 8.81e-18 Initial pursuit acceleration; LIHC cis rs240764 0.604 rs705583 chr6:101261408 C/A cg09795085 chr6:101329169 ASCC3 0.55 7.75 0.39 1.06e-13 Neuroticism; LIHC cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.06e-10 Bipolar disorder; LIHC cis rs9916302 0.768 rs62077464 chr17:37656056 C/G cg07936489 chr17:37558343 FBXL20 -0.84 -13.4 -0.59 3.27e-33 Glomerular filtration rate (creatinine); LIHC cis rs11122272 0.701 rs1009227 chr1:231480507 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -10.95 -0.51 4e-24 Hemoglobin concentration; LIHC cis rs2243480 1.000 rs2533288 chr7:66056711 C/G cg18252515 chr7:66147081 NA -1.33 -18.21 -0.7 2.75e-52 Diabetic kidney disease; LIHC cis rs2228479 0.702 rs11076620 chr16:89831520 A/T cg06558623 chr16:89946397 TCF25 0.85 11.71 0.53 7.62e-27 Skin colour saturation; LIHC cis rs1552244 0.572 rs7645667 chr3:10157337 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.89 -9.42 -0.45 7.12e-19 Alzheimer's disease; LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.07 -0.31 3.36e-9 Total body bone mineral density; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg12879381 chr18:12326166 TUBB6 0.41 6.06 0.31 3.65e-9 Immature fraction of reticulocytes; LIHC cis rs637571 0.522 rs1786175 chr11:65754808 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.2 0.45 3.58e-18 Eosinophil percentage of white cells; LIHC cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg05564831 chr3:52568323 NT5DC2 0.37 5.91 0.3 8.46e-9 Bipolar disorder; LIHC cis rs801193 0.548 rs7805152 chr7:66209253 C/T cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.34e-11 Aortic root size; LIHC cis rs9303401 0.659 rs17222691 chr17:56771096 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.2 0.55 1.13e-28 Cognitive test performance; LIHC cis rs763121 0.853 rs2072798 chr22:39148483 G/A cg14440974 chr22:39074834 NA -0.38 -6.26 -0.32 1.18e-9 Menopause (age at onset); LIHC cis rs7572733 0.534 rs1464209 chr2:198814396 A/G cg03934865 chr2:198174659 NA 0.48 6.95 0.35 1.88e-11 Dermatomyositis; LIHC cis rs4638749 0.677 rs10454132 chr2:108828111 T/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.98 -0.35 1.54e-11 Blood pressure; LIHC cis rs4423214 0.959 rs12794668 chr11:71168715 C/T cg05163923 chr11:71159392 DHCR7 0.89 13.63 0.59 4.49e-34 Vitamin D levels; LIHC cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg16049864 chr8:95962084 TP53INP1 -0.55 -9.67 -0.46 1.04e-19 Type 2 diabetes; LIHC cis rs7027203 0.828 rs3996239 chr9:96611290 T/A cg14598338 chr9:96623480 NA -0.34 -6.81 -0.35 4.5e-11 DNA methylation (variation); LIHC cis rs6545883 0.929 rs2463100 chr2:61659199 C/G cg14146966 chr2:61757674 XPO1 0.42 6.92 0.35 2.22e-11 Tuberculosis; LIHC cis rs7312933 0.531 rs2708059 chr12:42851008 C/T cg01256987 chr12:42539512 GXYLT1 0.36 5.95 0.31 6.57e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4788570 0.697 rs4788559 chr16:71848959 T/C cg06353428 chr16:71660113 MARVELD3 1.29 13.29 0.58 8.47e-33 Intelligence (multi-trait analysis); LIHC cis rs4474465 0.850 rs6592789 chr11:78246767 G/C cg02023728 chr11:77925099 USP35 -0.36 -6.36 -0.33 6.49e-10 Alzheimer's disease (survival time); LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg10755058 chr3:40428713 ENTPD3 -0.4 -6.93 -0.35 2.06e-11 Renal cell carcinoma; LIHC cis rs9560113 1.000 rs9560109 chr13:112180468 C/T cg14154082 chr13:112174009 NA 0.3 6.31 0.32 8.82e-10 Menarche (age at onset); LIHC cis rs243505 0.528 rs6977453 chr7:148474746 A/G cg09806900 chr7:148480153 CUL1 0.43 6.48 0.33 3.26e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs7940866 0.740 rs2162060 chr11:130830763 A/G cg12179176 chr11:130786555 SNX19 0.62 8.98 0.44 1.83e-17 Schizophrenia; LIHC cis rs727563 0.635 rs5751141 chr22:42107745 A/G cg06634786 chr22:41940651 POLR3H 0.61 6.16 0.32 2.01e-9 Crohn's disease;Inflammatory bowel disease; LIHC cis rs6933660 0.720 rs6913515 chr6:151753470 G/C cg14262678 chr6:151773367 RMND1;C6orf211 0.51 7.59 0.38 3.15e-13 Menarche (age at onset); LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg22903471 chr2:27725779 GCKR -0.5 -8.54 -0.42 4.55e-16 Total body bone mineral density; LIHC cis rs12579753 0.879 rs1987116 chr12:82156478 G/A cg07988820 chr12:82153109 PPFIA2 -0.49 -5.94 -0.31 6.82e-9 Resting heart rate; LIHC cis rs1008375 0.902 rs12503164 chr4:17656107 C/T cg15017067 chr4:17643749 FAM184B 0.34 5.86 0.3 1.08e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4803468 1.000 rs11880539 chr19:41918949 A/C cg14132834 chr19:41945861 ATP5SL 0.41 6.03 0.31 4.15e-9 Height; LIHC cis rs875971 0.893 rs62465470 chr7:65601218 T/C cg18252515 chr7:66147081 NA 0.42 5.88 0.3 9.66e-9 Aortic root size; LIHC cis rs801193 1.000 rs3857688 chr7:66127806 G/A cg11764359 chr7:65958608 NA -0.71 -10.55 -0.5 1.05e-22 Aortic root size; LIHC cis rs10508774 1.000 rs12268559 chr10:32856746 A/C cg01819863 chr10:32635814 EPC1 0.65 6.1 0.31 2.87e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg13607699 chr17:42295918 UBTF 0.44 7.13 0.36 6.14e-12 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09864156 chr10:70939728 SUPV3L1 0.42 6.68 0.34 9.55e-11 Pancreatic cancer; LIHC cis rs7613875 0.654 rs3774751 chr3:50209053 G/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.48 -7.07 -0.36 8.55e-12 Body mass index; LIHC cis rs10744422 1.000 rs10744434 chr12:123368419 T/A cg18912006 chr12:123335444 HIP1R -0.6 -7.27 -0.37 2.47e-12 Schizophrenia; LIHC cis rs6964587 1.000 rs2299232 chr7:91626699 A/C cg17063962 chr7:91808500 NA 0.99 18.86 0.71 6.53e-55 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11932961 chr4:129733571 PHF17 0.49 6.12 0.31 2.55e-9 Lung function (FEV1/FVC); LIHC cis rs35661897 0.920 rs12476220 chr2:227312391 A/C cg03426602 chr2:227312417 NA 0.55 5.78 0.3 1.69e-8 Urinary tract infection frequency; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg24846343 chr22:24311635 DDTL 0.63 11.96 0.54 8.57e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2842992 0.830 rs2495279 chr6:160138796 C/T cg11366901 chr6:160182831 ACAT2 0.95 16.21 0.66 2.97e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg13607699 chr17:42295918 UBTF 0.44 7.12 0.36 6.38e-12 Total body bone mineral density; LIHC cis rs9419702 0.568 rs9419635 chr10:133546164 C/T cg04492858 chr10:133558786 NA 0.45 6.67 0.34 1.05e-10 Survival in rectal cancer; LIHC cis rs765787 0.530 rs2554457 chr15:45520926 G/A cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.7e-10 Uric acid levels; LIHC cis rs11098499 0.743 rs11098501 chr4:120252017 T/G cg09307838 chr4:120376055 NA 0.71 11.02 0.51 2.19e-24 Corneal astigmatism; LIHC cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg23758822 chr17:41437982 NA 0.94 17.81 0.69 1.1e-50 Menopause (age at onset); LIHC cis rs3213545 0.676 rs1179998 chr12:121483653 G/A cg02403541 chr12:121454288 C12orf43 0.45 7.6 0.38 2.87e-13 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs763121 0.853 rs138713 chr22:39142615 T/C cg06544989 chr22:39130855 UNC84B 0.4 6.36 0.33 6.44e-10 Menopause (age at onset); LIHC cis rs11792861 0.926 rs1044905 chr9:111781495 G/A cg05043794 chr9:111880884 C9orf5 -0.3 -6.98 -0.35 1.58e-11 Menarche (age at onset); LIHC cis rs908922 0.676 rs545418 chr1:152497338 C/T cg23254163 chr1:152506842 NA 0.23 5.91 0.3 8.5e-9 Hair morphology; LIHC cis rs4906332 1.000 rs12885234 chr14:103889181 A/G cg19000871 chr14:103996768 TRMT61A -0.46 -7.85 -0.39 5.38e-14 Coronary artery disease; LIHC cis rs2932538 0.922 rs6658555 chr1:113098534 C/T cg22162597 chr1:113214053 CAPZA1 0.69 9.28 0.45 1.94e-18 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs61990749 0.597 rs1549119 chr14:78219812 A/T cg23188588 chr14:78226832 SNW1;C14orf178 0.63 10.53 0.49 1.23e-22 Fibroblast growth factor basic levels; LIHC cis rs11711311 0.866 rs13313893 chr3:113400856 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.35 6.14 0.32 2.27e-9 IgG glycosylation; LIHC cis rs9811920 0.638 rs704581 chr3:99556160 A/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.4 -5.73 -0.3 2.15e-8 Axial length; LIHC cis rs10779751 0.770 rs12097293 chr1:11197467 A/G cg08854313 chr1:11322531 MTOR -0.78 -10.28 -0.49 8.57e-22 Body mass index; LIHC cis rs2120019 1.000 rs7162900 chr15:75368017 T/C cg09165964 chr15:75287851 SCAMP5 -0.58 -9.38 -0.45 9.54e-19 Blood trace element (Zn levels); LIHC cis rs6546550 0.901 rs34586537 chr2:70163316 G/T cg02498382 chr2:70120550 SNRNP27 0.41 7.21 0.36 3.67e-12 Prevalent atrial fibrillation; LIHC cis rs8177179 0.967 rs4994582 chr3:133437566 G/C cg18769074 chr3:133464867 TF 0.26 5.78 0.3 1.64e-8 Iron status biomarkers (transferrin levels); LIHC cis rs3736485 0.673 rs8033234 chr15:51956117 T/C cg08986416 chr15:51914746 DMXL2 -0.43 -5.95 -0.31 6.65e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2439831 0.850 rs7163245 chr15:43671294 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.92 17.31 0.68 1.2e-48 Lung cancer in ever smokers; LIHC cis rs7615952 0.551 rs12695470 chr3:125635718 C/A cg05084668 chr3:125655381 ALG1L -0.6 -8.51 -0.42 5.57e-16 Blood pressure (smoking interaction); LIHC cis rs3796352 1.000 rs35849389 chr3:53005235 A/G cg07884673 chr3:53033167 SFMBT1 0.9 6.59 0.34 1.65e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs10504229 0.871 rs10504226 chr8:58159283 A/G cg02290350 chr8:58132656 NA 0.36 7.69 0.38 1.53e-13 Developmental language disorder (linguistic errors); LIHC cis rs734999 0.545 rs12752515 chr1:2564465 T/C cg18854424 chr1:2615690 NA -0.33 -7.13 -0.36 6.07e-12 Ulcerative colitis; LIHC cis rs11676348 0.818 rs7423433 chr2:218985084 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.06 -0.31 3.56e-9 Ulcerative colitis; LIHC cis rs3011225 0.710 rs3011222 chr1:44317545 C/T cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Amyotrophic lateral sclerosis (age of onset); LIHC cis rs7412746 0.658 rs11204750 chr1:150939744 C/A cg18016565 chr1:150552671 MCL1 0.51 9.67 0.46 1.03e-19 Melanoma; LIHC cis rs12477438 0.798 rs4851179 chr2:99568774 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.72 -0.5 2.54e-23 Chronic sinus infection; LIHC cis rs7937890 0.559 rs2597200 chr11:14485600 A/G cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs11760633 0.615 rs62435650 chr7:1823265 A/G cg23422044 chr7:1970798 MAD1L1 -0.37 -5.79 -0.3 1.59e-8 Coronary artery disease; LIHC cis rs2153535 0.580 rs4140586 chr6:8503192 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.94 0.39 2.95e-14 Motion sickness; LIHC cis rs10504073 0.584 rs56068225 chr8:49923988 A/G cg00325661 chr8:49890786 NA 0.4 9.54 0.46 2.73e-19 Blood metabolite ratios; LIHC cis rs782590 0.967 rs10496050 chr2:55806313 C/T cg03859395 chr2:55845619 SMEK2 0.86 15.36 0.64 7.32e-41 Metabolic syndrome; LIHC cis rs12908161 1.000 rs34900908 chr15:85257599 G/A cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC cis rs79976124 0.877 rs79507557 chr6:66640908 C/A cg07460842 chr6:66804631 NA 0.66 7.02 0.35 1.22e-11 Type 2 diabetes; LIHC cis rs10744422 1.000 rs10744434 chr12:123368419 T/A cg07706471 chr12:123319906 HIP1R -0.59 -7.83 -0.39 6.07e-14 Schizophrenia; LIHC cis rs10791323 0.593 rs11223599 chr11:133717902 A/T cg06766960 chr11:133703094 NA 0.58 9.81 0.47 3.55e-20 Childhood ear infection; LIHC cis rs1577917 1.000 rs35419329 chr6:86702291 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.81 -0.47 3.57e-20 Response to antipsychotic treatment; LIHC cis rs7100689 0.753 rs1572816 chr10:82137600 A/G cg00277334 chr10:82204260 NA -0.54 -6.66 -0.34 1.11e-10 Post bronchodilator FEV1; LIHC trans rs11165623 0.792 rs9437607 chr1:96977788 G/A cg10631902 chr5:14652156 NA -0.31 -7.08 -0.36 8.09e-12 Hip circumference;Waist circumference; LIHC cis rs947211 0.950 rs1775145 chr1:205756143 C/A cg14893161 chr1:205819251 PM20D1 0.34 5.91 0.3 8.36e-9 Parkinson's disease; LIHC cis rs11971779 0.838 rs4728468 chr7:139122978 G/A cg07862535 chr7:139043722 LUC7L2 0.6 9.89 0.47 1.85e-20 Diisocyanate-induced asthma; LIHC cis rs10423674 0.526 rs11668545 chr19:18829529 C/T cg14292368 chr19:18793705 CRTC1 -0.42 -5.83 -0.3 1.28e-8 Menarche (age at onset); LIHC cis rs523522 0.962 rs2393590 chr12:120913900 G/A cg12219531 chr12:120966889 COQ5 0.65 12.59 0.56 3.92e-30 High light scatter reticulocyte count; LIHC cis rs6061231 0.837 rs6061235 chr20:60978524 C/G cg24112000 chr20:60950667 NA -0.62 -8.2 -0.41 5.05e-15 Colorectal cancer; LIHC cis rs708547 0.575 rs6847086 chr4:57791864 A/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.5 -7.06 -0.36 9.45e-12 Response to bleomycin (chromatid breaks); LIHC cis rs765787 0.530 rs7165889 chr15:45531640 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs10193935 0.901 rs12622153 chr2:42598386 C/A cg27598129 chr2:42591480 NA -0.75 -11.66 -0.53 1.16e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg10862848 chr6:42927986 GNMT -0.26 -6.23 -0.32 1.36e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1865760 1.000 rs3799371 chr6:25912816 A/G cg03517284 chr6:25882590 NA 0.39 5.8 0.3 1.54e-8 Height; LIHC cis rs3096299 0.933 rs2965824 chr16:89455306 A/G cg06640241 chr16:89574553 SPG7 0.59 9.4 0.45 7.89e-19 Multiple myeloma (IgH translocation); LIHC cis rs385076 0.562 rs1119292 chr2:32045773 C/T cg02381751 chr2:32503542 YIPF4 -0.41 -5.73 -0.3 2.16e-8 Interleukin-18 levels; LIHC cis rs6450176 1.000 rs60492935 chr5:53306240 G/T ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.66 -0.62 4.37e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs2797160 1.000 rs6904069 chr6:125995134 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.47 -6.88 -0.35 2.85e-11 Endometrial cancer; LIHC cis rs7216064 1.000 rs4318247 chr17:65882172 A/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.35 -0.45 1.16e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9814567 0.806 rs6799543 chr3:134216139 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.07 -0.31 3.42e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7772486 0.875 rs6938972 chr6:146410608 G/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.11 -0.31 2.78e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.659 rs17822735 chr17:56620167 C/T cg25039879 chr17:56429692 SUPT4H1 0.75 8.44 0.42 8.81e-16 Cognitive test performance; LIHC cis rs1499614 1.000 rs34250985 chr7:66161062 A/T cg12463550 chr7:65579703 CRCP 0.69 6.62 0.34 1.42e-10 Gout; LIHC cis rs922107 0.738 rs12410381 chr1:90036694 T/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.6 -0.38 2.8e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs1577917 0.696 rs10806334 chr6:86439329 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.49 -9.52 -0.46 3.37e-19 Response to antipsychotic treatment; LIHC trans rs1499614 1.000 rs2707840 chr7:66158015 C/T cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs11148252 0.574 rs7139495 chr13:53283318 A/G cg12458913 chr13:53173898 NA 0.48 7.89 0.39 4.16e-14 Lewy body disease; LIHC cis rs919433 0.963 rs1896854 chr2:198147776 G/T cg10820045 chr2:198174542 NA -0.6 -10.24 -0.48 1.25e-21 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs965469 0.724 rs6051818 chr20:3362033 T/C cg25506879 chr20:3388711 C20orf194 -0.52 -6.37 -0.33 6.27e-10 IFN-related cytopenia; LIHC cis rs1419980 0.673 rs7296837 chr12:7757832 A/G cg14906510 chr12:7781169 NA 0.48 7.36 0.37 1.4e-12 HDL cholesterol levels; LIHC cis rs240764 0.697 rs239194 chr6:101131959 G/A cg09795085 chr6:101329169 ASCC3 0.45 6.12 0.31 2.5e-9 Neuroticism; LIHC cis rs7520050 0.966 rs4660321 chr1:46366760 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 5.97 0.31 5.87e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7582720 1.000 rs72932553 chr2:203842661 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs561341 0.700 rs886223 chr17:30229877 G/T cg13647721 chr17:30228624 UTP6 0.76 8.52 0.42 5.17e-16 Hip circumference adjusted for BMI; LIHC cis rs1577917 0.916 rs12206726 chr6:86499716 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.85 -0.39 5.25e-14 Response to antipsychotic treatment; LIHC cis rs6840360 1.000 rs3749561 chr4:152610117 C/T cg22705602 chr4:152727874 NA 0.32 6.95 0.35 1.84e-11 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs28815867 chr15:45526805 G/C cg25801113 chr15:45476975 SHF 0.37 6.36 0.33 6.62e-10 Uric acid levels; LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg05185784 chr16:90016020 DEF8 -0.43 -5.87 -0.3 1.04e-8 Skin colour saturation; LIHC cis rs9814567 1.000 rs7645295 chr3:134307734 T/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.87 -0.3 1e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1865760 0.566 rs1971509 chr6:26085777 T/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC cis rs7903847 0.619 rs10786336 chr10:99134953 A/C cg08345082 chr10:99160200 RRP12 -0.37 -6.13 -0.31 2.37e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs922107 0.738 rs35176344 chr1:90045973 T/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.79 -0.39 8.16e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg03517284 chr6:25882590 NA -0.48 -7.32 -0.37 1.73e-12 Height; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg11494091 chr17:61959527 GH2 0.44 7.89 0.39 4.06e-14 Prudent dietary pattern; LIHC cis rs801193 0.548 rs2659904 chr7:66178602 C/A cg11764359 chr7:65958608 NA 0.83 14.36 0.61 6.26e-37 Aortic root size; LIHC cis rs2334880 0.836 rs9939458 chr16:71667131 T/G cg06353428 chr16:71660113 MARVELD3 1.46 15.76 0.65 1.89e-42 Malaria; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17697381 chr3:148709363 GYG1 0.45 6.58 0.34 1.77e-10 Lung function (FEV1/FVC); LIHC cis rs67311347 1.000 rs11716675 chr3:40485280 G/T cg24209194 chr3:40518798 ZNF619 0.49 7.37 0.37 1.32e-12 Renal cell carcinoma; LIHC cis rs9372253 0.645 rs7753212 chr6:110700229 T/C cg19196401 chr6:110721138 DDO -0.33 -6.7 -0.34 8.75e-11 Platelet distribution width; LIHC cis rs2991971 0.810 rs781058 chr1:45935056 C/G cg15605315 chr1:45957053 TESK2 -0.5 -7.19 -0.36 4.09e-12 High light scatter reticulocyte count; LIHC cis rs7208859 0.673 rs11652370 chr17:29097223 G/A cg14067834 chr17:29058358 SUZ12P 0.65 6.66 0.34 1.08e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg20090690 chr10:134436459 INPP5A 0.44 5.78 0.3 1.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg06873352 chr17:61820015 STRADA 0.52 7.56 0.38 3.63e-13 Height; LIHC cis rs9814567 1.000 rs35718987 chr3:134272783 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9326248 0.520 rs2735183 chr11:117015195 C/T cg26566898 chr11:117069891 TAGLN 0.39 6.0 0.31 5.02e-9 Blood protein levels; LIHC cis rs6500602 0.627 rs3848372 chr16:4587875 C/A cg08645402 chr16:4508243 NA 0.33 5.9 0.3 8.66e-9 Schizophrenia; LIHC cis rs1023500 0.552 rs133368 chr22:42463689 T/C cg00645731 chr22:42541494 CYP2D7P1 0.39 6.21 0.32 1.51e-9 Schizophrenia; LIHC cis rs35110281 0.748 rs9981460 chr21:45030965 T/A cg01579765 chr21:45077557 HSF2BP -0.35 -6.58 -0.34 1.72e-10 Mean corpuscular volume; LIHC cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg03264133 chr6:25882463 NA -0.62 -8.73 -0.43 1.12e-16 Blood metabolite levels; LIHC cis rs10857712 0.784 rs2265639 chr10:135221576 C/G cg19623624 chr10:135278901 LOC619207 0.42 6.52 0.33 2.55e-10 Systemic lupus erythematosus; LIHC trans rs12310956 0.532 rs1589903 chr12:33943019 C/T cg26384229 chr12:38710491 ALG10B 0.51 7.05 0.36 9.76e-12 Morning vs. evening chronotype; LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.53 -7.5 -0.38 5.53e-13 Lymphocyte counts; LIHC cis rs11677370 0.574 rs11686118 chr2:3854938 C/T cg17052675 chr2:3827356 NA -0.49 -6.0 -0.31 5.05e-9 Type 2 diabetes; LIHC cis rs5769765 0.817 rs11912619 chr22:50317401 G/A cg09182678 chr22:50328711 NA -0.41 -6.05 -0.31 3.72e-9 Schizophrenia; LIHC cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.95 -10.5 -0.49 1.5e-22 Platelet count; LIHC cis rs2637266 1.000 rs2637267 chr10:78331803 A/G cg18941641 chr10:78392320 NA 0.27 5.73 0.3 2.18e-8 Pulmonary function; LIHC cis rs8063761 0.640 rs4785760 chr16:90051438 G/A cg12064134 chr16:90016061 DEF8 0.36 5.96 0.31 6.14e-9 Squamous cell carcinoma; LIHC cis rs12644436 0.587 rs6853109 chr4:88783555 A/G cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs116095464 0.558 rs113796397 chr5:246503 A/G cg22857025 chr5:266934 NA -1.46 -17.61 -0.69 7.47e-50 Breast cancer; LIHC cis rs11190604 1.000 rs7079756 chr10:102302105 G/A cg07080220 chr10:102295463 HIF1AN 0.52 7.37 0.37 1.34e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6430585 0.583 rs2304371 chr2:136561557 A/G cg25344623 chr2:136566232 LCT -0.38 -6.48 -0.33 3.11e-10 Corneal structure; LIHC cis rs4319547 0.915 rs10773208 chr12:122970156 T/C cg23029597 chr12:123009494 RSRC2 -0.54 -7.7 -0.38 1.5e-13 Body mass index; LIHC cis rs9543976 0.858 rs9530447 chr13:76166802 G/A cg01531495 chr13:76123901 UCHL3 0.48 5.75 0.3 1.98e-8 Diabetic retinopathy; LIHC cis rs1757171 0.542 rs3818985 chr6:37484214 G/T cg08126542 chr6:37504118 NA -0.37 -6.27 -0.32 1.09e-9 Cognitive performance; LIHC cis rs17253792 0.545 rs3742570 chr14:56016434 A/C cg01858014 chr14:56050164 KTN1 -0.72 -6.6 -0.34 1.61e-10 Putamen volume; LIHC cis rs7534824 0.582 rs17448827 chr1:101421407 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.23 0.36 3.17e-12 Refractive astigmatism; LIHC cis rs12497850 0.864 rs7431857 chr3:48900347 G/A cg07636037 chr3:49044803 WDR6 0.93 16.99 0.68 2.33e-47 Parkinson's disease; LIHC cis rs1401999 0.650 rs3749445 chr3:183638506 C/T cg01324343 chr3:183735012 ABCC5 0.53 8.35 0.41 1.71e-15 Anterior chamber depth; LIHC cis rs1552244 0.882 rs3846168 chr3:9996925 C/T cg08888203 chr3:10149979 C3orf24 0.46 5.85 0.3 1.18e-8 Alzheimer's disease; LIHC cis rs644799 1.000 rs693597 chr11:95589629 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.89 16.39 0.66 5.75e-45 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg17971929 chr21:40555470 PSMG1 0.75 8.56 0.42 3.87e-16 Cognitive function; LIHC cis rs1552244 0.554 rs3846167 chr3:9996426 T/C cg21531657 chr3:10005747 TMEM111 0.4 6.14 0.31 2.34e-9 Alzheimer's disease; LIHC cis rs7914558 0.933 rs10786729 chr10:104719378 A/G cg15744005 chr10:104629667 AS3MT -0.4 -9.16 -0.44 4.98e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg02782426 chr3:40428986 ENTPD3 0.35 6.4 0.33 5.16e-10 Renal cell carcinoma; LIHC cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg25897951 chr4:1244024 CTBP1;C4orf42 -0.4 -5.83 -0.3 1.31e-8 Longevity; LIHC cis rs1046896 0.594 rs67813226 chr17:80851134 G/A cg19500275 chr17:80737654 TBCD 0.44 6.07 0.31 3.46e-9 Glycated hemoglobin levels; LIHC cis rs1348850 0.567 rs880898 chr2:178532470 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 8.12 0.4 8.81e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4423214 0.592 rs11233977 chr11:71221605 C/T cg05163923 chr11:71159392 DHCR7 -0.56 -6.93 -0.35 2.13e-11 Vitamin D levels; LIHC cis rs4727027 0.901 rs1534198 chr7:148772323 T/C cg23583168 chr7:148888333 NA -0.68 -9.33 -0.45 1.41e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs769267 0.896 rs10410664 chr19:19556651 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.0 0.4 1.99e-14 Tonsillectomy; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18368637 chr6:144179905 LTV1 0.48 6.3 0.32 9.15e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1865760 1.000 rs3799371 chr6:25912816 A/G cg17691542 chr6:26056736 HIST1H1C -0.41 -6.01 -0.31 4.87e-9 Height; LIHC cis rs1552244 0.554 rs2272120 chr3:10046703 C/T cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs7116495 0.881 rs1573500 chr11:71732790 C/G cg26138937 chr11:71823887 C11orf51 -0.69 -6.97 -0.35 1.69e-11 Severe influenza A (H1N1) infection; LIHC cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg23982607 chr1:1823379 GNB1 -0.75 -15.39 -0.64 5.8e-41 Body mass index; LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg04013166 chr16:89971882 TCF25 0.55 7.16 0.36 4.96e-12 Skin colour saturation; LIHC cis rs9393692 0.905 rs9379843 chr6:26289435 A/G cg13736514 chr6:26305472 NA -0.37 -6.13 -0.31 2.37e-9 Educational attainment; LIHC cis rs6088580 0.634 rs4911152 chr20:32955024 T/C cg08999081 chr20:33150536 PIGU -0.66 -13.27 -0.58 1.05e-32 Glomerular filtration rate (creatinine); LIHC trans rs61931739 0.500 rs11053251 chr12:34520743 A/G cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs11098499 0.730 rs78971550 chr4:120281041 C/T cg09307838 chr4:120376055 NA 0.63 9.05 0.44 1.07e-17 Corneal astigmatism; LIHC cis rs8027181 1.000 rs8027181 chr15:73088869 A/T cg25632853 chr15:73088954 NA 0.38 6.32 0.32 7.95e-10 Triglyceride levels; LIHC cis rs8141529 0.753 rs5752813 chr22:29226570 T/G cg15103426 chr22:29168792 CCDC117 0.67 11.37 0.52 1.29e-25 Lymphocyte counts; LIHC cis rs765787 0.530 rs2413780 chr15:45538866 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg16049864 chr8:95962084 TP53INP1 -0.59 -11.39 -0.52 1.08e-25 Type 2 diabetes; LIHC cis rs1577917 0.655 rs12203963 chr6:86223316 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.43 7.9 0.39 3.88e-14 Response to antipsychotic treatment; LIHC trans rs7874142 0.616 rs10858280 chr9:137687875 A/G cg18109838 chr5:88185987 MEF2C -0.39 -7.74 -0.39 1.15e-13 Longevity; LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs2033711 0.870 rs1465789 chr19:58946056 C/T cg13877915 chr19:58951672 ZNF132 0.58 9.04 0.44 1.19e-17 Uric acid clearance; LIHC cis rs12980942 1.000 rs34945449 chr19:41819824 T/C cg25627403 chr19:41769009 HNRNPUL1 0.48 5.88 0.3 9.67e-9 Coronary artery disease; LIHC cis rs9430161 0.579 rs11121669 chr1:11039567 T/C cg27631724 chr1:11040367 C1orf127 0.37 7.44 0.37 8.21e-13 Ewing sarcoma; LIHC cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg23205692 chr1:25664452 TMEM50A 0.37 5.97 0.31 5.87e-9 Erythrocyte sedimentation rate; LIHC cis rs3096299 0.933 rs28608022 chr16:89454292 C/T cg01788221 chr16:89496183 ANKRD11 -0.39 -6.13 -0.31 2.49e-9 Multiple myeloma (IgH translocation); LIHC cis rs881375 1.000 rs4323544 chr9:123647377 C/T cg14580859 chr9:123691850 NA 0.39 6.78 0.34 5.43e-11 Rheumatoid arthritis; LIHC cis rs12477438 0.520 rs11689265 chr2:99799267 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.2 0.64 3.05e-40 Chronic sinus infection; LIHC cis rs240764 0.711 rs240112 chr6:101059253 C/A cg09795085 chr6:101329169 ASCC3 0.5 6.89 0.35 2.64e-11 Neuroticism; LIHC cis rs1113500 0.836 rs1122158 chr1:108588668 G/T cg06207961 chr1:108661230 NA 0.36 6.93 0.35 2.05e-11 Growth-regulated protein alpha levels; LIHC cis rs7208859 0.623 rs73269916 chr17:29096326 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.1 0.4 1.01e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg27170947 chr2:26402098 FAM59B 0.66 8.24 0.41 3.72e-15 Gut microbiome composition (summer); LIHC cis rs2439831 0.850 rs28513374 chr15:44125495 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.69 0.43 1.58e-16 Lung cancer in ever smokers; LIHC cis rs12101261 0.580 rs3783950 chr14:81448282 C/G cg06600135 chr14:81408086 NA -0.41 -7.53 -0.38 4.63e-13 Graves' disease; LIHC cis rs875971 1.000 rs2077593 chr7:65892530 A/G cg18876405 chr7:65276391 NA 0.38 6.95 0.35 1.91e-11 Aortic root size; LIHC cis rs8062405 0.755 rs4788074 chr16:28593597 A/G cg16576597 chr16:28551801 NUPR1 -0.49 -7.67 -0.38 1.78e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7769051 1.000 rs9493444 chr6:133125320 C/G cg07930552 chr6:133119739 C6orf192 0.67 6.36 0.33 6.45e-10 Type 2 diabetes nephropathy; LIHC cis rs10905065 1.000 rs10737013 chr10:5746772 C/G cg11519256 chr10:5708881 ASB13 0.46 6.09 0.31 2.97e-9 Menopause (age at onset); LIHC cis rs1568889 1.000 rs16917735 chr11:28119980 A/T cg06544937 chr11:28130018 METT5D1;KIF18A -0.49 -6.8 -0.35 4.62e-11 Bipolar disorder; LIHC cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg05590025 chr7:65112418 INTS4L2 -0.62 -6.7 -0.34 8.76e-11 Diabetic kidney disease; LIHC cis rs644799 0.965 rs566877 chr11:95528045 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3099143 1.000 rs1913001 chr15:77179408 A/C cg21673338 chr15:77095150 SCAPER 0.51 7.83 0.39 6.19e-14 Recalcitrant atopic dermatitis; LIHC cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg03517284 chr6:25882590 NA -0.6 -8.51 -0.42 5.64e-16 Blood metabolite levels; LIHC cis rs3736485 0.966 rs11070860 chr15:51892654 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.29 -0.32 9.87e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11105298 0.838 rs10858862 chr12:89842053 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.37 -0.37 1.25e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs79387448 0.614 rs6719130 chr2:102958236 C/T cg09003973 chr2:102972529 NA 1.12 10.33 0.49 5.96e-22 Gut microbiota (bacterial taxa); LIHC cis rs12644436 0.711 rs13107383 chr4:88787535 C/A cg06891869 chr4:88767617 MEPE 0.42 7.6 0.38 2.93e-13 HIV-1 viral setpoint; LIHC trans rs17685 0.712 rs4732578 chr7:75721532 A/G cg19862616 chr7:65841803 NCRNA00174 0.92 18.56 0.71 1.05e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9811920 0.609 rs9872871 chr3:99658702 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.15 0.36 5.37e-12 Axial length; LIHC cis rs875971 0.862 rs2420174 chr7:65645361 C/T cg18252515 chr7:66147081 NA 0.42 5.77 0.3 1.79e-8 Aortic root size; LIHC cis rs921968 0.643 rs539451 chr2:219426972 T/C cg17980119 chr2:219472607 PLCD4 0.35 5.91 0.3 8.24e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs780096 0.546 rs4425043 chr2:27733452 G/A cg22903471 chr2:27725779 GCKR -0.53 -8.96 -0.44 2.16e-17 Total body bone mineral density; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg23179321 chr10:15138793 C10orf111;RPP38 -0.54 -6.12 -0.31 2.61e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs800082 0.668 rs7643301 chr3:144293612 G/A cg24215973 chr2:240111563 HDAC4 -0.58 -8.85 -0.43 4.93e-17 Smoking behavior; LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg21724239 chr8:58056113 NA 0.58 7.75 0.39 1.05e-13 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg06634786 chr22:41940651 POLR3H -0.79 -8.69 -0.43 1.55e-16 Vitiligo; LIHC cis rs2997447 0.653 rs2802329 chr1:26466189 T/C cg19633962 chr1:26362018 EXTL1 -0.54 -6.2 -0.32 1.66e-9 QRS complex (12-leadsum); LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg11494091 chr17:61959527 GH2 0.43 8.07 0.4 1.21e-14 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg00280220 chr17:61926910 NA 0.43 6.89 0.35 2.76e-11 Prudent dietary pattern; LIHC cis rs7224314 1.000 rs62085808 chr17:65357692 G/A cg01507342 chr17:65387096 PITPNC1 -0.45 -5.77 -0.3 1.82e-8 Diisocyanate-induced asthma; LIHC cis rs4665809 0.652 rs6728090 chr2:26524726 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.95 -14.75 -0.62 1.81e-38 Gut microbiome composition (summer); LIHC trans rs7618501 0.633 rs7621026 chr3:49975334 A/G cg21659725 chr3:3221576 CRBN 0.66 10.66 0.5 4.41e-23 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.690 rs1599390 chr3:160833246 A/G cg03342759 chr3:160939853 NMD3 -0.72 -11.07 -0.51 1.45e-24 Morning vs. evening chronotype; LIHC cis rs807669 0.548 rs723414 chr22:19185736 G/A cg02655711 chr22:19163373 SLC25A1 0.35 6.1 0.31 2.94e-9 Metabolite levels; LIHC cis rs79057730 0.599 rs4720893 chr7:804434 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.83 9.14 0.44 5.75e-18 Initial pursuit acceleration; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg01301323 chr12:77252588 CSRP2 0.44 6.26 0.32 1.13e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.3 -6.16 -0.32 1.99e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg23982607 chr1:1823379 GNB1 -0.69 -13.57 -0.59 7.32e-34 Body mass index; LIHC cis rs1843834 0.505 rs4674911 chr2:225345254 A/G cg22455342 chr2:225449267 CUL3 0.58 8.45 0.42 8.34e-16 IgE levels in asthmatics (D.p. specific); LIHC cis rs477692 0.597 rs574831 chr10:131379190 C/T cg05714579 chr10:131428358 MGMT -0.45 -7.5 -0.38 5.7e-13 Response to temozolomide; LIHC cis rs2153535 0.563 rs3117071 chr6:8537908 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.47 0.42 7.58e-16 Motion sickness; LIHC cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 11.76 0.54 4.64e-27 Alzheimer's disease; LIHC cis rs12824058 0.831 rs11060825 chr12:130807905 A/G cg24838063 chr12:130822603 PIWIL1 0.67 9.82 0.47 3.13e-20 Menopause (age at onset); LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.0 0.58 1.11e-31 Prudent dietary pattern; LIHC cis rs6684514 1.000 rs12117951 chr1:156305286 G/A cg16558208 chr1:156270281 VHLL 0.55 10.45 0.49 2.28e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs943466 0.955 rs2281819 chr6:33771673 T/A cg25922239 chr6:33757077 LEMD2 -0.53 -7.11 -0.36 6.99e-12 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs36051895 0.632 rs10115962 chr9:5140841 T/C cg02405213 chr9:5042618 JAK2 -0.68 -11.83 -0.54 2.67e-27 Pediatric autoimmune diseases; LIHC cis rs1419980 0.730 rs11054699 chr12:7744539 G/A cg10578777 chr12:7781093 NA -0.39 -5.74 -0.3 2.04e-8 HDL cholesterol levels; LIHC cis rs7091068 0.671 rs1764322 chr10:95406276 T/G cg20715218 chr10:95462985 C10orf4 -0.55 -6.42 -0.33 4.57e-10 Urinary tract infection frequency; LIHC cis rs6963495 0.818 rs1355614 chr7:105179176 A/G cg19920283 chr7:105172520 RINT1 0.75 8.57 0.42 3.69e-16 Bipolar disorder (body mass index interaction); LIHC cis rs1005277 0.579 rs11011461 chr10:38431427 G/A cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs600806 0.888 rs3853501 chr1:109864374 G/A cg23091122 chr1:110024289 SYPL2 -0.46 -6.06 -0.31 3.63e-9 Intelligence (multi-trait analysis); LIHC cis rs7072216 0.806 rs9804285 chr10:100169472 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.32 -0.32 8.18e-10 Metabolite levels; LIHC cis rs7534824 0.625 rs17409422 chr1:101502386 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.77 7.1 0.36 7.05e-12 Refractive astigmatism; LIHC cis rs2257205 0.667 rs9909763 chr17:56629640 C/T cg12560992 chr17:57184187 TRIM37 0.68 7.68 0.38 1.64e-13 Pancreatic cancer; LIHC cis rs67478160 0.643 rs3742369 chr14:104251276 T/C cg08213375 chr14:104286397 PPP1R13B 0.65 12.42 0.56 1.74e-29 Schizophrenia; LIHC cis rs1395 0.848 rs6716850 chr2:27525350 G/A cg22903471 chr2:27725779 GCKR -0.37 -5.75 -0.3 1.93e-8 Blood metabolite levels; LIHC cis rs688020 1.000 rs688020 chr7:4228553 C/T cg02004499 chr7:4244250 SDK1 0.43 7.98 0.4 2.3e-14 Liver fibrosis in pediatric non-alcoholic fatty acid liver disease; LIHC cis rs11945232 1.000 rs10027786 chr4:88347512 A/G cg23841344 chr4:88312519 HSD17B11 -0.58 -7.46 -0.37 7.16e-13 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 6.02 0.31 4.41e-9 Schizophrenia; LIHC cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg09455208 chr3:40491958 NA -0.33 -6.58 -0.34 1.77e-10 Renal cell carcinoma; LIHC cis rs4474465 0.850 rs10793329 chr11:78265655 G/C cg27205649 chr11:78285834 NARS2 0.44 6.64 0.34 1.22e-10 Alzheimer's disease (survival time); LIHC cis rs8063761 0.589 rs4238833 chr16:90050689 G/T cg05185784 chr16:90016020 DEF8 0.38 6.35 0.32 6.81e-10 Squamous cell carcinoma; LIHC cis rs72781680 0.898 rs55841168 chr2:24007926 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs7666738 0.830 rs4699574 chr4:98725544 C/T cg05340658 chr4:99064831 C4orf37 0.64 11.61 0.53 1.65e-26 Colonoscopy-negative controls vs population controls; LIHC trans rs8073060 0.586 rs6505485 chr17:33996102 C/T cg19694781 chr19:47549865 TMEM160 -1.15 -12.04 -0.55 4.49e-28 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs17401966 1.000 rs12129035 chr1:10291166 G/A cg15208524 chr1:10270712 KIF1B 0.44 6.38 0.33 5.61e-10 Hepatocellular carcinoma; LIHC cis rs2839186 0.706 rs2839188 chr21:47692798 C/T cg12379764 chr21:47803548 PCNT -0.57 -7.93 -0.39 3.13e-14 Testicular germ cell tumor; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14431619 chr19:11266544 SPC24 0.44 6.41 0.33 4.88e-10 Pancreatic cancer; LIHC cis rs7208859 0.673 rs9895815 chr17:29138033 A/G cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12477438 0.765 rs7607578 chr2:99669771 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs67478160 0.643 rs6575999 chr14:104250609 C/G cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.47 -0.37 6.56e-13 Schizophrenia; LIHC cis rs769267 0.930 rs1054930 chr19:19648346 G/C cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.66 0.38 1.9e-13 Tonsillectomy; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10238396 chr2:64067940 UGP2 -0.51 -6.32 -0.32 8.3e-10 Systolic blood pressure; LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg02635209 chr6:118822505 C6orf204;BRD7P3 0.49 5.74 0.3 2.1e-8 Diastolic blood pressure; LIHC cis rs9916302 0.904 rs650106 chr17:37451559 A/G cg03013999 chr17:37608204 MED1 -0.36 -6.07 -0.31 3.33e-9 Glomerular filtration rate (creatinine); LIHC cis rs798554 0.660 rs1182196 chr7:2866478 T/G cg19717773 chr7:2847554 GNA12 -0.44 -7.69 -0.38 1.61e-13 Height; LIHC cis rs8177253 0.514 rs6790668 chr3:133442481 T/A cg18769074 chr3:133464867 TF 0.26 6.11 0.31 2.64e-9 Iron status biomarkers; LIHC cis rs5769765 0.657 rs8136116 chr22:50256886 T/A cg09182678 chr22:50328711 NA 0.47 6.0 0.31 5.14e-9 Schizophrenia; LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.61 0.46 1.58e-19 Height; LIHC cis rs921968 0.541 rs562510 chr2:219443001 A/C cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.37e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs9291683 0.632 rs13137074 chr4:10042842 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.63e-13 Bone mineral density; LIHC cis rs2439831 0.867 rs2260160 chr15:43895643 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.06 0.44 9.98e-18 Lung cancer in ever smokers; LIHC cis rs986417 0.792 rs4901990 chr14:61015474 C/T cg27398547 chr14:60952738 C14orf39 -0.75 -7.77 -0.39 9.43e-14 Gut microbiota (bacterial taxa); LIHC cis rs4974559 0.739 rs1250121 chr4:1263521 A/G cg02980000 chr4:1222292 CTBP1 -0.75 -5.8 -0.3 1.54e-8 Systolic blood pressure; LIHC cis rs9381040 0.610 rs2268195 chr6:41024340 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.02 -0.31 4.41e-9 Alzheimer's disease (late onset); LIHC cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg10802521 chr3:52805072 NEK4 -0.45 -7.73 -0.39 1.2e-13 Bipolar disorder; LIHC cis rs6088580 0.634 rs1890000 chr20:32968312 G/T cg08999081 chr20:33150536 PIGU -0.67 -13.32 -0.58 6.54e-33 Glomerular filtration rate (creatinine); LIHC cis rs7520050 0.966 rs6680380 chr1:46300189 T/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.75 0.3 2.03e-8 Red blood cell count;Reticulocyte count; LIHC cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg10755058 chr3:40428713 ENTPD3 0.38 6.37 0.33 6.25e-10 Renal cell carcinoma; LIHC cis rs1577917 0.958 rs12665542 chr6:86544443 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.14 -0.52 8.66e-25 Response to antipsychotic treatment; LIHC cis rs7772486 0.686 rs1415744 chr6:146022531 C/T cg23711669 chr6:146136114 FBXO30 0.7 13.15 0.58 3.03e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs919433 0.679 rs6741314 chr2:198526088 G/A cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs546131 0.642 rs11605381 chr11:34847193 T/A cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.49 -0.33 3.05e-10 Lung disease severity in cystic fibrosis; LIHC cis rs7107174 1.000 rs2511175 chr11:77975081 A/G cg02023728 chr11:77925099 USP35 0.5 9.61 0.46 1.62e-19 Testicular germ cell tumor; LIHC cis rs2204008 0.688 rs12824232 chr12:38175901 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs11588062 0.628 rs3737744 chr1:46810530 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 -0.44 -6.89 -0.35 2.72e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6502050 0.749 rs7406163 chr17:80086389 C/T cg13198984 chr17:80129470 CCDC57 -0.33 -5.8 -0.3 1.54e-8 Life satisfaction; LIHC trans rs1814175 0.645 rs847639 chr11:49919603 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs7651039 0.641 rs2455810 chr3:15657082 A/T cg16303742 chr3:15540471 COLQ 0.55 9.63 0.46 1.43e-19 Coronary heart disease; LIHC cis rs2839627 0.561 rs6586250 chr21:44270229 C/T cg18192155 chr21:44258298 NA 0.45 7.12 0.36 6.21e-12 Information processing speed; LIHC trans rs2847476 0.690 rs7929497 chr11:114192132 C/G cg04426326 chr15:59499030 LDHAL6B;MYO1E -0.36 -6.05 -0.31 3.81e-9 Volumetric brain MRI; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23347958 chr17:41561300 DHX8 -0.55 -6.41 -0.33 4.76e-10 Systolic blood pressure; LIHC cis rs4073582 0.595 rs528842 chr11:66032390 G/A cg16950941 chr11:66035639 RAB1B 0.6 9.12 0.44 6.67e-18 Gout; LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg04267008 chr7:1944627 MAD1L1 -0.67 -11.02 -0.51 2.34e-24 Bipolar disorder and schizophrenia; LIHC cis rs6754311 0.731 rs892715 chr2:136576577 T/C cg25344623 chr2:136566232 LCT 0.42 8.59 0.42 3.11e-16 Mosquito bite size; LIHC cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg00750074 chr16:89608354 SPG7 -0.38 -5.89 -0.3 9.38e-9 Multiple myeloma (IgH translocation); LIHC cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg05564831 chr3:52568323 NT5DC2 0.38 6.13 0.31 2.4e-9 Bipolar disorder; LIHC cis rs2180341 1.000 rs6904520 chr6:127629802 T/C cg24812749 chr6:127587940 RNF146 1.07 16.09 0.66 9.4e-44 Breast cancer; LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg11494091 chr17:61959527 GH2 -0.4 -7.27 -0.37 2.52e-12 Prudent dietary pattern; LIHC cis rs11583043 0.918 rs11582211 chr1:101416871 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 8.19 0.4 5.3e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg11494091 chr17:61959527 GH2 0.36 5.96 0.31 6.31e-9 Height; LIHC cis rs7091068 0.518 rs726817 chr10:95459817 C/T cg20715218 chr10:95462985 C10orf4 0.59 8.43 0.41 1.01e-15 Urinary tract infection frequency; LIHC cis rs4759375 0.598 rs4759359 chr12:123398454 C/G cg25930673 chr12:123319894 HIP1R -0.66 -8.05 -0.4 1.38e-14 HDL cholesterol; LIHC cis rs2235642 0.717 rs9937922 chr16:1658154 C/G cg09025071 chr16:1593152 IFT140;TMEM204 0.31 6.13 0.31 2.43e-9 Coronary artery disease; LIHC cis rs2404602 0.647 rs116090606 chr15:77075209 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.54 -0.46 2.86e-19 Blood metabolite levels; LIHC cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs1707322 0.963 rs12076580 chr1:46258159 G/A cg06784218 chr1:46089804 CCDC17 0.39 6.9 0.35 2.6e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8103278 0.507 rs522769 chr19:46284520 G/A cg14061069 chr19:46274453 DMPK 0.72 13.38 0.59 3.82e-33 Coronary artery disease; LIHC cis rs9378688 0.654 rs35224259 chr6:2363505 G/A cg12303981 chr6:2244766 GMDS 0.47 6.28 0.32 1.04e-9 Caudate nucleus volume; LIHC cis rs6951245 0.935 rs112554101 chr7:1065535 A/G cg08132940 chr7:1081526 C7orf50 -0.69 -6.53 -0.33 2.34e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg05590025 chr7:65112418 INTS4L2 -0.57 -6.2 -0.32 1.67e-9 Diabetic kidney disease; LIHC cis rs5769765 0.908 rs9616216 chr22:50318927 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.41 -0.45 7.59e-19 Schizophrenia; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg20684973 chr10:105127632 TAF5 -0.56 -6.16 -0.32 1.99e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg13409248 chr3:40428643 ENTPD3 0.41 6.77 0.34 5.65e-11 Renal cell carcinoma; LIHC trans rs7937682 0.924 rs7924683 chr11:111555796 C/A cg18187862 chr3:45730750 SACM1L 0.56 6.06 0.31 3.53e-9 Primary sclerosing cholangitis; LIHC cis rs3020736 0.500 rs6002605 chr22:42494335 A/G cg15557168 chr22:42548783 NA 0.44 6.95 0.35 1.81e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs875971 0.895 rs6460278 chr7:65662736 T/C cg11764359 chr7:65958608 NA -0.75 -12.45 -0.56 1.34e-29 Aortic root size; LIHC cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg25364880 chr3:44379878 C3orf23 -0.53 -7.33 -0.37 1.72e-12 Depressive symptoms; LIHC cis rs9916302 0.861 rs12150493 chr17:37586154 T/C cg00129232 chr17:37814104 STARD3 -0.4 -6.43 -0.33 4.4e-10 Glomerular filtration rate (creatinine); LIHC cis rs875971 0.545 rs13311962 chr7:66068129 C/T cg11764359 chr7:65958608 NA -0.63 -9.08 -0.44 8.81e-18 Aortic root size; LIHC trans rs208520 1.000 rs72882102 chr6:66983408 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.09 0.36 7.85e-12 Exhaled nitric oxide output; LIHC cis rs3096299 0.869 rs748941 chr16:89440754 T/A cg02187348 chr16:89574699 SPG7 0.44 6.41 0.33 4.8e-10 Multiple myeloma (IgH translocation); LIHC cis rs10464366 0.517 rs13231075 chr7:39174806 G/T cg10621924 chr7:39171070 POU6F2 0.41 6.45 0.33 3.86e-10 IgG glycosylation; LIHC cis rs13392177 0.543 rs12623716 chr2:219073018 C/T cg00012203 chr2:219082015 ARPC2 -0.73 -10.78 -0.5 1.58e-23 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg08677398 chr8:58056175 NA 0.42 5.73 0.3 2.2e-8 Developmental language disorder (linguistic errors); LIHC trans rs12310956 0.532 rs35366144 chr12:33992000 C/G cg26384229 chr12:38710491 ALG10B 0.51 7.09 0.36 7.78e-12 Morning vs. evening chronotype; LIHC cis rs7044106 0.762 rs10984974 chr9:123421556 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.79 0.39 8.28e-14 Hip circumference adjusted for BMI; LIHC cis rs3099143 1.000 rs2011635 chr15:77134891 T/A cg21673338 chr15:77095150 SCAPER -0.49 -7.06 -0.36 9.4e-12 Recalcitrant atopic dermatitis; LIHC cis rs4820294 0.516 rs12627943 chr22:38096334 C/G cg26138144 chr22:38071188 LGALS1 0.71 10.35 0.49 5.19e-22 Fat distribution (HIV); LIHC cis rs7216064 1.000 rs2052187 chr17:65834737 T/C cg12091567 chr17:66097778 LOC651250 -0.65 -9.56 -0.46 2.36e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs743757 1.000 rs743857 chr3:50493550 T/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.16 0.32 2.04e-9 Diastolic blood pressure; LIHC cis rs2439831 0.681 rs11858152 chr15:43634196 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.53 0.53 3.36e-26 Lung cancer in ever smokers; LIHC cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg18305652 chr10:134549665 INPP5A 0.51 7.94 0.39 2.96e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2153535 0.584 rs9502721 chr6:8541379 G/A cg07606381 chr6:8435919 SLC35B3 0.78 11.22 0.52 4.23e-25 Motion sickness; LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg26769984 chr7:1090371 C7orf50 0.47 5.84 0.3 1.22e-8 Bronchopulmonary dysplasia; LIHC trans rs3780486 0.846 rs10124479 chr9:33136233 T/G cg04842962 chr6:43655489 MRPS18A 1.08 25.4 0.81 1.05e-80 IgG glycosylation; LIHC trans rs3813567 0.702 rs7164665 chr15:78953919 T/C cg24133106 chr7:129690864 ZC3HC1 -0.49 -6.11 -0.31 2.68e-9 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg07157834 chr1:205819609 PM20D1 0.77 11.8 0.54 3.47e-27 Menarche (age at onset); LIHC cis rs6062302 0.522 rs2297427 chr20:62221364 G/A cg16989086 chr20:62203971 PRIC285 0.57 8.13 0.4 7.82e-15 Glioblastoma; LIHC cis rs7552404 1.000 rs4949879 chr1:76237143 G/A cg22875332 chr1:76189707 ACADM 0.45 6.39 0.33 5.32e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs611744 0.816 rs626211 chr8:109189448 A/C cg18478394 chr8:109455254 TTC35 0.41 6.73 0.34 7.31e-11 Dupuytren's disease; LIHC cis rs9486715 0.830 rs2475023 chr6:96996833 G/A cg18709589 chr6:96969512 KIAA0776 -0.33 -5.77 -0.3 1.79e-8 Headache; LIHC cis rs2354432 0.607 rs55918563 chr1:146718973 G/C cg25205988 chr1:146714368 CHD1L -0.89 -10.59 -0.5 7.24e-23 Mitochondrial DNA levels; LIHC cis rs1059312 0.808 rs12831705 chr12:129294905 G/A cg09035930 chr12:129282057 SLC15A4 0.59 11.13 0.52 9.02e-25 Systemic lupus erythematosus; LIHC cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg11062466 chr8:58055876 NA 0.52 7.54 0.38 4.33e-13 Developmental language disorder (linguistic errors); LIHC cis rs78545713 0.536 rs78759249 chr6:26208956 G/A cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs769267 0.965 rs12977937 chr19:19429975 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.62 10.0 0.48 7.88e-21 Tonsillectomy; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg00656387 chr3:40428638 ENTPD3 0.49 8.06 0.4 1.29e-14 Renal cell carcinoma; LIHC cis rs7772486 0.536 rs9373467 chr6:145955605 C/T cg13319975 chr6:146136371 FBXO30 -0.56 -8.71 -0.43 1.29e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.541 rs6932434 chr6:8467679 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08386886 chr17:41277274 BRCA1;NBR2 0.49 6.35 0.32 6.87e-10 Lung function (FEV1/FVC); LIHC cis rs7208859 0.673 rs216409 chr17:28906269 C/T cg14067834 chr17:29058358 SUZ12P -0.65 -6.88 -0.35 2.9e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3540 0.597 rs10152221 chr15:91047664 A/G cg22089800 chr15:90895588 ZNF774 -0.59 -8.27 -0.41 3.07e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs1707322 1.000 rs6429580 chr1:46275648 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.41 0.33 4.77e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17818399 0.788 rs13013245 chr2:46806086 T/C cg02822958 chr2:46747628 ATP6V1E2 0.47 7.15 0.36 5.3e-12 Height; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03344030 chr19:48673649 LIG1 -0.47 -6.61 -0.34 1.46e-10 Systolic blood pressure; LIHC cis rs34779708 0.931 rs11010082 chr10:35351155 A/G cg03585969 chr10:35415529 CREM 0.8 11.92 0.54 1.26e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs16870629 0.541 rs2334955 chr5:1062444 A/G cg08382946 chr5:1082689 SLC12A7 0.42 6.34 0.32 7.06e-10 QT interval; LIHC cis rs655641 1.000 rs627818 chr11:85698207 A/T cg09030501 chr11:85779252 PICALM -0.49 -6.0 -0.31 4.89e-9 Platelet count; LIHC cis rs35110281 0.776 rs62226866 chr21:45024186 T/C cg04455712 chr21:45112962 RRP1B 0.45 7.53 0.38 4.54e-13 Mean corpuscular volume; LIHC cis rs17826219 0.568 rs7213925 chr17:29121634 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Body mass index; LIHC cis rs8060686 0.641 rs7201742 chr16:68099821 T/G cg05110241 chr16:68378359 PRMT7 -0.57 -6.78 -0.34 5.35e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs7116495 0.609 rs7924834 chr11:71644333 C/T cg10381502 chr11:71823885 C11orf51 0.82 7.73 0.39 1.19e-13 Severe influenza A (H1N1) infection; LIHC trans rs800082 0.702 rs1726522 chr3:144253391 A/G cg24215973 chr2:240111563 HDAC4 -0.44 -6.51 -0.33 2.66e-10 Smoking behavior; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11234017 chr17:42767172 CCDC43 0.41 6.8 0.35 4.69e-11 Cognitive function; LIHC cis rs904251 0.523 rs2776920 chr6:37480605 G/A cg08126542 chr6:37504118 NA -0.36 -6.14 -0.31 2.35e-9 Cognitive performance; LIHC cis rs9419702 0.639 rs4367873 chr10:133533485 C/T cg04492858 chr10:133558786 NA 0.44 6.42 0.33 4.59e-10 Survival in rectal cancer; LIHC cis rs10779751 1.000 rs4845859 chr1:11304873 A/G cg08854313 chr1:11322531 MTOR 0.82 11.65 0.53 1.17e-26 Body mass index; LIHC cis rs2576037 0.583 rs9304336 chr18:44461687 T/C cg19077165 chr18:44547161 KATNAL2 -0.46 -6.96 -0.35 1.71e-11 Personality dimensions; LIHC cis rs6782228 0.606 rs2811497 chr3:128363332 C/T cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7528419 0.895 rs599839 chr1:109822166 A/G cg20569855 chr1:109824440 PSRC1 -0.46 -6.21 -0.32 1.56e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC trans rs6934970 1.000 rs17759304 chr6:113099084 C/T cg09308777 chr6:169852575 NA -0.65 -6.9 -0.35 2.46e-11 Bipolar disorder (body mass index interaction); LIHC cis rs727505 1.000 rs67939974 chr7:124554364 C/T cg23710748 chr7:124431027 NA -0.32 -5.72 -0.3 2.32e-8 Lewy body disease; LIHC trans rs208520 0.690 rs4710311 chr6:66823223 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.7 -8.09 -0.4 1.07e-14 Exhaled nitric oxide output; LIHC cis rs11122272 0.668 rs1122131 chr1:231476501 A/G cg06096015 chr1:231504339 EGLN1 0.47 8.74 0.43 1.06e-16 Hemoglobin concentration; LIHC cis rs7927592 0.956 rs12281742 chr11:68303629 C/T cg20283391 chr11:68216788 NA 0.51 7.83 0.39 6.08e-14 Total body bone mineral density; LIHC trans rs9858542 0.903 rs11921590 chr3:49644193 T/C cg21659725 chr3:3221576 CRBN -0.6 -6.52 -0.33 2.6e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1577917 0.740 rs2842614 chr6:86306069 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.29 -0.32 9.49e-10 Response to antipsychotic treatment; LIHC cis rs10751667 0.961 rs10794358 chr11:985547 C/T cg10932868 chr11:921992 NA 0.35 6.47 0.33 3.47e-10 Alzheimer's disease (late onset); LIHC cis rs1005277 0.579 rs2472176 chr10:38382921 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15643885 chr8:17434749 PDGFRL 0.47 6.25 0.32 1.19e-9 Lung function (FEV1/FVC); LIHC cis rs950169 0.686 rs12906474 chr15:85109237 A/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.42 0.41 1.02e-15 Schizophrenia; LIHC cis rs2204008 0.805 rs11514348 chr12:38243427 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.77 0.3 1.81e-8 Bladder cancer; LIHC cis rs10197940 0.638 rs2288193 chr2:152348842 T/A cg19508488 chr2:152266495 RIF1 0.57 7.98 0.4 2.26e-14 Lung cancer; LIHC cis rs9733 0.596 rs72702573 chr1:150689050 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs250677 0.687 rs250679 chr5:148434952 A/T cg18129178 chr5:148520854 ABLIM3 0.48 7.48 0.37 6.4e-13 Breast cancer; LIHC cis rs1144333 0.655 rs11162053 chr1:76470267 A/C cg03433033 chr1:76189801 ACADM 0.52 7.62 0.38 2.52e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs1278769 0.786 rs3742238 chr13:113540425 C/T cg00823993 chr13:113535758 ATP11A 0.6 7.32 0.37 1.79e-12 Interstitial lung disease; LIHC cis rs4589502 0.800 rs2035150 chr15:67201794 A/C cg09911534 chr15:67153556 NA 0.44 6.87 0.35 2.98e-11 Lung cancer (smoking interaction); LIHC cis rs3096299 0.967 rs2965827 chr16:89457350 A/C cg06640241 chr16:89574553 SPG7 -0.65 -10.73 -0.5 2.45e-23 Multiple myeloma (IgH translocation); LIHC cis rs1200821 0.559 rs9418267 chr10:37819951 A/G cg25427524 chr10:38739819 LOC399744 0.46 7.8 0.39 7.36e-14 Hemostatic factors and hematological phenotypes; LIHC cis rs8067354 0.645 rs11079389 chr17:57887952 G/A cg02344993 chr17:57696989 CLTC 0.73 12.38 0.56 2.54e-29 Hemoglobin concentration; LIHC cis rs7927771 0.524 rs11039419 chr11:47851354 C/T cg20307385 chr11:47447363 PSMC3 0.75 11.14 0.52 8.26e-25 Subjective well-being; LIHC trans rs11552708 0.504 rs9890935 chr17:7391282 A/G cg08566640 chr11:64091735 NA -0.67 -6.1 -0.31 2.84e-9 IgM levels; LIHC cis rs9896933 0.775 rs79299098 chr17:80830944 G/A cg20578329 chr17:80767326 TBCD -0.7 -6.71 -0.34 8.24e-11 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs4820294 1.000 rs41280035 chr22:38054038 A/G cg00292662 chr22:38071168 LGALS1 0.59 9.32 0.45 1.53e-18 Fat distribution (HIV); LIHC trans rs7618501 0.521 rs55692411 chr3:49911155 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.7 0.34 8.35e-11 Intelligence (multi-trait analysis); LIHC cis rs899997 1.000 rs11633170 chr15:79004642 A/G cg04896959 chr15:78267971 NA -0.33 -5.93 -0.31 7.24e-9 Coronary artery disease or large artery stroke; LIHC cis rs11098499 0.588 rs6534149 chr4:120559292 T/G cg09307838 chr4:120376055 NA -0.57 -8.73 -0.43 1.17e-16 Corneal astigmatism; LIHC trans rs11010290 0.639 rs752431 chr10:36038275 A/G cg08927738 chr20:52687394 BCAS1 -0.47 -6.28 -0.32 1e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; LIHC trans rs66887589 0.560 rs9684327 chr4:120365441 A/G cg25214090 chr10:38739885 LOC399744 0.41 6.9 0.35 2.51e-11 Diastolic blood pressure; LIHC cis rs7412746 0.658 rs11204723 chr1:150731618 T/C cg18016565 chr1:150552671 MCL1 0.54 10.05 0.48 5.25e-21 Melanoma; LIHC cis rs801193 1.000 rs2659906 chr7:66165310 T/C cg18876405 chr7:65276391 NA 0.43 7.38 0.37 1.24e-12 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13501090 chr1:115212659 DENND2C 0.5 7.18 0.36 4.35e-12 Lung function (FEV1/FVC); LIHC cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg08888203 chr3:10149979 C3orf24 0.59 6.93 0.35 2.13e-11 Alzheimer's disease; LIHC cis rs765787 0.530 rs4775832 chr15:45534828 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs11627756 0.958 rs2146431 chr14:103071861 A/G cg12046867 chr14:103022105 NA 0.42 6.48 0.33 3.12e-10 Mean platelet volume; LIHC cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.04 -0.48 5.96e-21 Platelet count; LIHC cis rs7945705 0.875 rs2568065 chr11:8889648 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -9.12 -0.44 6.53e-18 Hemoglobin concentration; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.85 -0.3 1.16e-8 Total body bone mineral density; LIHC cis rs965469 1.000 rs2236089 chr20:3257194 C/A cg25506879 chr20:3388711 C20orf194 -0.62 -7.11 -0.36 7.02e-12 IFN-related cytopenia; LIHC cis rs17685 0.816 rs11763076 chr7:75765963 C/T cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8062405 1.000 rs62036626 chr16:28844284 A/G cg07451762 chr16:28383216 NA 0.32 6.05 0.31 3.83e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9921222 0.502 rs28461430 chr16:369562 G/A cg00101154 chr16:420108 MRPL28 -0.6 -8.22 -0.41 4.17e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs17685 0.664 rs9801113 chr7:75792031 C/T cg04610667 chr7:75704037 NA -0.35 -6.21 -0.32 1.54e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs743757 1.000 rs2073496 chr3:50431142 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.64 0.38 2.23e-13 Diastolic blood pressure; LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg11342453 chr6:26196699 NA 0.53 5.92 0.3 7.83e-9 Gout;Renal underexcretion gout; LIHC cis rs6964587 1.000 rs411 chr7:91557758 C/G cg17063962 chr7:91808500 NA -1.02 -19.52 -0.73 1.47e-57 Breast cancer; LIHC cis rs1555322 0.530 rs2425044 chr20:33869735 C/T cg03689076 chr20:33865952 NA 0.58 6.66 0.34 1.06e-10 Attention deficit hyperactivity disorder; LIHC cis rs13191362 1.000 rs13193282 chr6:163015442 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.82 0.3 1.32e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs801193 0.548 rs6975044 chr7:66227482 C/T cg18252515 chr7:66147081 NA -0.49 -7.19 -0.36 4.17e-12 Aortic root size; LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg06656553 chr16:89960601 TCF25 -0.48 -6.09 -0.31 3.09e-9 Skin colour saturation; LIHC cis rs11864453 1.000 rs1035559 chr16:72031860 A/G cg01557791 chr16:72042693 DHODH -0.73 -11.51 -0.53 3.99e-26 Fibrinogen levels; LIHC cis rs2073300 0.536 rs6137947 chr20:23414630 C/A cg12062639 chr20:23401060 NAPB 1.02 12.94 0.57 1.96e-31 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs769267 1.000 rs3764567 chr19:19440066 C/T cg03709012 chr19:19516395 GATAD2A -0.9 -14.98 -0.63 2.27e-39 Tonsillectomy; LIHC cis rs933688 0.938 rs7705465 chr5:90680949 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.69 0.73 3.11e-58 Smoking behavior; LIHC cis rs1577917 1.000 rs13196930 chr6:86652245 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.27 -0.49 9.61e-22 Response to antipsychotic treatment; LIHC cis rs2839186 0.721 rs3788252 chr21:47661235 C/T cg12379764 chr21:47803548 PCNT -0.57 -8.36 -0.41 1.65e-15 Testicular germ cell tumor; LIHC cis rs600806 0.745 rs4970763 chr1:110006349 G/A cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.21 -0.32 1.54e-9 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.611 rs111842513 chr1:150712926 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.82 -0.3 1.34e-8 Melanoma; LIHC cis rs10540 0.686 rs12806099 chr11:531572 G/A cg03352830 chr11:487213 PTDSS2 0.8 6.45 0.33 3.76e-10 Body mass index; LIHC cis rs7412746 0.658 rs6658066 chr1:150918937 T/G cg18016565 chr1:150552671 MCL1 0.49 9.26 0.45 2.3e-18 Melanoma; LIHC cis rs3924048 0.574 rs12096486 chr1:12616911 T/C cg00291366 chr1:12616550 NA 0.43 8.92 0.43 2.79e-17 Optic cup area; LIHC trans rs1728785 0.892 rs1103955 chr16:68588488 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.36 0.33 6.63e-10 Ulcerative colitis; LIHC cis rs4843747 0.671 rs28465438 chr16:88103714 G/A cg00677901 chr16:88017247 BANP 0.55 8.53 0.42 4.67e-16 Menopause (age at onset); LIHC cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg13395646 chr4:1353034 KIAA1530 -0.59 -8.73 -0.43 1.12e-16 Obesity-related traits; LIHC cis rs875971 1.000 rs6956179 chr7:65806659 C/T cg18252515 chr7:66147081 NA 0.45 6.36 0.33 6.61e-10 Aortic root size; LIHC cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg22618164 chr12:122356400 WDR66 0.57 8.17 0.4 6.01e-15 Mean corpuscular volume; LIHC cis rs2354432 0.607 rs6689243 chr1:146710559 A/T cg25205988 chr1:146714368 CHD1L -0.9 -10.74 -0.5 2.29e-23 Mitochondrial DNA levels; LIHC cis rs7264396 0.790 rs3746410 chr20:34190870 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -9.62 -0.46 1.5700000000000001e-19 Total cholesterol levels; LIHC cis rs17345786 0.906 rs59359251 chr3:101146362 A/C cg12386194 chr3:101231763 SENP7 0.6 7.87 0.39 4.57e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs6570726 0.791 rs12205752 chr6:145896118 A/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.37 -0.33 6.08e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs965469 1.000 rs6051703 chr20:3252347 A/T cg25506879 chr20:3388711 C20orf194 -0.58 -6.99 -0.35 1.44e-11 IFN-related cytopenia; LIHC cis rs9522267 0.535 rs9522299 chr13:112236013 C/A cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs875971 0.617 rs810400 chr7:66022889 G/C cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg06873352 chr17:61820015 STRADA 0.74 13.21 0.58 1.74e-32 Prudent dietary pattern; LIHC cis rs921968 0.678 rs660432 chr2:219432127 C/T cg17980119 chr2:219472607 PLCD4 0.34 5.79 0.3 1.62e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs903552 1.000 rs34937195 chr15:102003631 C/A cg06707286 chr15:102010195 PCSK6 -0.44 -6.33 -0.32 7.48e-10 Diabetic kidney disease; LIHC cis rs9399135 0.967 rs1014020 chr6:135334426 C/A cg22676075 chr6:135203613 NA 0.39 6.32 0.32 7.93e-10 Red blood cell count; LIHC cis rs67311347 1.000 rs2887995 chr3:40409029 C/G cg09455208 chr3:40491958 NA 0.33 6.55 0.33 2.06e-10 Renal cell carcinoma; LIHC cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.33 0.41 1.99e-15 Platelet count; LIHC cis rs2274273 0.840 rs1045002 chr14:55818517 T/A cg01864836 chr14:55583639 NA -0.38 -6.66 -0.34 1.08e-10 Protein biomarker; LIHC cis rs5769765 0.730 rs62233964 chr22:50317410 C/G cg09182678 chr22:50328711 NA -0.41 -6.05 -0.31 3.72e-9 Schizophrenia; LIHC cis rs6831352 0.918 rs7670060 chr4:100059568 G/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs1113500 0.787 rs10881501 chr1:108641745 C/T cg06207961 chr1:108661230 NA 0.31 6.07 0.31 3.43e-9 Growth-regulated protein alpha levels; LIHC cis rs10927875 0.631 rs28579893 chr1:16347534 A/G cg21385522 chr1:16154831 NA 0.72 9.38 0.45 9.41e-19 Dilated cardiomyopathy; LIHC cis rs4665809 1.000 rs4665308 chr2:26330514 C/A cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs936229 0.690 rs2472300 chr15:75033909 A/G cg14664628 chr15:75095509 CSK -0.84 -13.89 -0.6 4.23e-35 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs2153535 0.580 rs1832100 chr6:8446956 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.84 0.43 5.15e-17 Motion sickness; LIHC cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg06238570 chr21:40685208 BRWD1 -0.55 -9.18 -0.44 4.21e-18 Cognitive function; LIHC cis rs600806 0.815 rs10858088 chr1:109923586 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.658 rs11181310 chr12:38315963 C/A cg26384229 chr12:38710491 ALG10B 0.6 8.2 0.41 4.99e-15 Bladder cancer; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg08030934 chr13:21678628 NA 0.45 6.81 0.35 4.3e-11 Bilirubin levels; LIHC cis rs1400745 0.756 rs799682 chr14:35349984 G/C cg16230307 chr14:35515116 FAM177A1 0.39 6.21 0.32 1.5e-9 Monocyte count; LIHC cis rs7647973 0.696 rs7100 chr3:49053219 A/G cg07636037 chr3:49044803 WDR6 0.76 9.09 0.44 8.16e-18 Menarche (age at onset); LIHC trans rs4596713 0.508 rs13289984 chr9:71775047 A/C cg16512924 chr15:28394682 HERC2 0.39 6.25 0.32 1.21e-9 Headache; LIHC cis rs611744 0.868 rs612722 chr8:109194850 C/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs611744 0.934 rs672408 chr8:109224390 A/G cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs546131 0.642 rs2915186 chr11:34851183 C/T cg11058730 chr11:34937778 PDHX;APIP 0.64 9.37 0.45 1e-18 Lung disease severity in cystic fibrosis; LIHC cis rs12101261 0.925 rs2300519 chr14:81458762 T/A cg06600135 chr14:81408086 NA 0.37 6.3 0.32 9.16e-10 Graves' disease; LIHC cis rs7592578 0.771 rs4439990 chr2:191398353 A/C cg10560079 chr2:191398806 TMEM194B -0.86 -12.53 -0.56 6.86e-30 Diastolic blood pressure; LIHC cis rs10751667 0.666 rs6597958 chr11:978087 C/T cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs10540 1.000 rs61876323 chr11:462855 G/A cg03352830 chr11:487213 PTDSS2 0.65 5.82 0.3 1.35e-8 Body mass index; LIHC cis rs5769707 0.521 rs6009807 chr22:50058922 A/G cg07959070 chr22:50026188 C22orf34 -0.3 -7.22 -0.36 3.33e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs10832963 0.924 rs10832950 chr11:18635815 A/G cg09201001 chr11:18656081 SPTY2D1 0.94 17.64 0.69 5.29e-50 Breast cancer; LIHC cis rs6598163 0.712 rs10751695 chr12:132291061 A/C cg00078996 chr12:132293329 NA -0.33 -6.12 -0.31 2.51e-9 Migraine; LIHC cis rs9322817 0.691 rs6907016 chr6:105211360 G/A cg02098413 chr6:105308735 HACE1 -0.42 -7.53 -0.38 4.46e-13 Thyroid stimulating hormone; LIHC cis rs9472202 1.000 rs9472202 chr6:44021286 C/T cg12481212 chr6:44020245 NA 0.39 6.57 0.33 1.9e-10 Behavioral disturbance or psychiatric symptoms in prion disease; LIHC cis rs17826219 0.706 rs8075107 chr17:29106649 C/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Body mass index; LIHC trans rs7618501 0.570 rs7613875 chr3:49971514 C/A cg21659725 chr3:3221576 CRBN 0.7 11.14 0.52 8.59e-25 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg08888203 chr3:10149979 C3orf24 0.62 6.95 0.35 1.81e-11 Alzheimer's disease; LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg22903471 chr2:27725779 GCKR -0.52 -9.03 -0.44 1.29e-17 Total body bone mineral density; LIHC cis rs3617 0.625 rs11715347 chr3:52883070 C/T cg11645453 chr3:52864694 ITIH4 -0.23 -6.18 -0.32 1.86e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs5769765 0.955 rs1321 chr22:50297435 A/G cg26441486 chr22:50317300 CRELD2 0.35 6.15 0.32 2.21e-9 Schizophrenia; LIHC cis rs910316 1.000 rs7145159 chr14:75583268 A/G cg11812906 chr14:75593930 NEK9 0.75 15.0 0.63 1.87e-39 Height; LIHC trans rs208520 0.954 rs12190073 chr6:66983740 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.09 0.36 7.85e-12 Exhaled nitric oxide output; LIHC cis rs11098499 0.863 rs10013305 chr4:120450424 G/A cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs73001065 0.818 rs16996185 chr19:19720788 G/T cg03709012 chr19:19516395 GATAD2A -0.81 -7.59 -0.38 3.15e-13 LDL cholesterol; LIHC cis rs11792861 0.781 rs28361106 chr9:111762385 T/C cg05043794 chr9:111880884 C9orf5 -0.32 -7.21 -0.36 3.56e-12 Menarche (age at onset); LIHC cis rs12479064 0.724 rs3792143 chr2:100057020 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -6.85 -0.35 3.54e-11 Chronic sinus infection; LIHC trans rs875971 0.545 rs6961853 chr7:66002022 G/A cg26939375 chr7:64535504 NA 0.4 6.31 0.32 8.63e-10 Aortic root size; LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg06558623 chr16:89946397 TCF25 -0.95 -14.63 -0.62 5.6e-38 Skin colour saturation; LIHC trans rs1814175 0.588 rs1721994 chr11:49914050 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs4631830 0.832 rs67289834 chr10:51501304 C/T cg20129853 chr10:51489980 NA 0.42 9.02 0.44 1.38e-17 Prostate-specific antigen levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03283842 chr2:179343803 FKBP7;PLEKHA3;MIR548N 0.43 6.16 0.32 2.04e-9 Pancreatic cancer; LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.51 7.26 0.37 2.56e-12 Lymphocyte counts; LIHC cis rs4629710 0.545 rs11755717 chr6:131547028 A/T cg12606694 chr6:131520996 AKAP7 -0.64 -7.47 -0.37 6.56e-13 Multiple myeloma (IgH translocation); LIHC cis rs4242434 0.854 rs3064 chr8:22451688 C/G cg03733263 chr8:22462867 KIAA1967 -0.79 -15.3 -0.64 1.25e-40 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs7615952 0.932 rs3811679 chr3:125648283 A/G cg05084668 chr3:125655381 ALG1L -0.57 -8.32 -0.41 2.14e-15 Blood pressure (smoking interaction); LIHC cis rs798554 0.660 rs2527694 chr7:2858240 T/C cg19717773 chr7:2847554 GNA12 -0.42 -7.55 -0.38 3.95e-13 Height; LIHC trans rs9929218 0.906 rs10852450 chr16:68749529 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -9.31 -0.45 1.56e-18 Colorectal cancer; LIHC cis rs9814567 0.929 rs9815297 chr3:134215052 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.66 -12.17 -0.55 1.5e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9457247 0.715 rs6923582 chr6:167437162 T/A cg07741184 chr6:167504864 NA 0.32 7.39 0.37 1.13e-12 Crohn's disease; LIHC cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg12310025 chr6:25882481 NA -0.8 -11.77 -0.54 4.58e-27 Blood metabolite levels; LIHC cis rs2304069 0.817 rs216132 chr5:149431259 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.92 -11.79 -0.54 3.72e-27 HIV-1 control; LIHC trans rs2726453 0.562 rs2713834 chr4:106310520 G/T cg02562419 chr6:159049626 TMEM181 0.45 6.17 0.32 1.92e-9 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg11494091 chr17:61959527 GH2 0.44 8.19 0.4 5.4e-15 Prudent dietary pattern; LIHC cis rs1348850 0.914 rs12104588 chr2:178253675 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 13.97 0.6 2.02e-35 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs763121 0.819 rs5757126 chr22:38923675 T/C cg06022373 chr22:39101656 GTPBP1 0.64 10.63 0.5 5.26e-23 Menopause (age at onset); LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg05025164 chr4:1340916 KIAA1530 0.8 12.76 0.57 9.12e-31 Longevity; LIHC cis rs2439831 0.850 rs28891769 chr15:44072860 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.43 0.33 4.32e-10 Lung cancer in ever smokers; LIHC cis rs2304069 0.545 rs4705404 chr5:149381952 A/C cg22760475 chr5:149380129 HMGXB3;TIGD6 0.61 8.72 0.43 1.19e-16 HIV-1 control; LIHC cis rs11864453 0.647 rs2550035 chr16:72113416 C/G cg16558253 chr16:72132732 DHX38 -0.45 -7.52 -0.38 4.8e-13 Fibrinogen levels; LIHC cis rs61990749 0.544 rs12435761 chr14:78246077 C/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.73 -0.39 1.18e-13 Fibroblast growth factor basic levels; LIHC cis rs1707322 0.686 rs2230659 chr1:46078884 C/T cg03146154 chr1:46216737 IPP -0.57 -9.53 -0.46 3.09e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17106184 1.000 rs12074982 chr1:51387415 T/C cg07174182 chr1:51127561 FAF1 -0.75 -7.63 -0.38 2.42e-13 Type 2 diabetes; LIHC cis rs4969178 0.620 rs7219625 chr17:76390080 C/T cg05887092 chr17:76393375 PGS1 0.35 6.66 0.34 1.08e-10 HDL cholesterol levels; LIHC cis rs4713118 0.513 rs149958 chr6:28013617 A/C cg23485639 chr6:28045615 ZNF165 0.38 5.87 0.3 1.03e-8 Parkinson's disease; LIHC cis rs798554 0.757 rs1713919 chr7:2864706 C/A cg13628971 chr7:2884303 GNA12 0.52 7.37 0.37 1.31e-12 Height; LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.86 0.39 5.2e-14 Prudent dietary pattern; LIHC cis rs9549367 0.789 rs2287250 chr13:113889474 C/T cg18105134 chr13:113819100 PROZ 0.56 10.02 0.48 7.09e-21 Platelet distribution width; LIHC cis rs2030401 0.603 rs1727301 chr12:123664514 G/A cg00376283 chr12:123451042 ABCB9 0.53 8.4 0.41 1.25e-15 Intelligence (multi-trait analysis); LIHC trans rs7606173 0.534 rs10445937 chr2:60637656 A/G cg08245425 chr17:34957834 MRM1 0.47 6.04 0.31 4.04e-9 F-cell distribution;Red cell distribution width; LIHC cis rs8078723 0.714 rs3859187 chr17:38150613 C/A cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.35 0.52 1.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2439831 1.000 rs690002 chr15:43729349 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.94 0.44 2.42e-17 Lung cancer in ever smokers; LIHC cis rs6701037 0.566 rs10753091 chr1:175134571 T/C cg00958927 chr1:175162553 KIAA0040 0.39 6.55 0.33 2.11e-10 Alcohol dependence; LIHC cis rs921968 0.509 rs3856548 chr2:219398164 C/T cg02985541 chr2:219472218 PLCD4 -0.42 -6.83 -0.35 3.99e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs11122272 0.525 rs61835222 chr1:231537917 C/A cg06096015 chr1:231504339 EGLN1 0.49 9.19 0.45 3.77e-18 Hemoglobin concentration; LIHC cis rs644148 0.785 rs117048220 chr19:44965555 G/A cg15540054 chr19:45004280 ZNF180 0.77 11.12 0.52 9.58e-25 Personality dimensions; LIHC cis rs422249 0.634 rs174615 chr11:61628964 T/A cg27386326 chr11:61587980 NA 0.33 5.78 0.3 1.67e-8 Trans fatty acid levels; LIHC cis rs7845219 0.544 rs34293080 chr8:95908078 G/T cg23172400 chr8:95962367 TP53INP1 -0.31 -5.82 -0.3 1.34e-8 Type 2 diabetes; LIHC cis rs7659604 0.539 rs56159666 chr4:122782879 G/A cg19748678 chr4:122722346 EXOSC9 0.67 11.13 0.52 9.02e-25 Type 2 diabetes; LIHC cis rs1185460 0.967 rs1168568 chr11:118949799 G/A cg23280166 chr11:118938394 VPS11 0.59 7.89 0.39 4.14e-14 Coronary artery disease; LIHC cis rs1707322 1.000 rs785469 chr1:46521091 C/T cg06784218 chr1:46089804 CCDC17 -0.36 -6.5 -0.33 2.8e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8062405 1.000 rs12444171 chr16:28845251 G/A cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs637571 0.546 rs11227309 chr11:65584512 A/C cg04055107 chr11:65626734 MUS81;CFL1 -0.43 -6.48 -0.33 3.22e-10 Eosinophil percentage of white cells; LIHC cis rs2153535 0.580 rs6938071 chr6:8464845 A/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs6912958 1.000 rs6912958 chr6:88133315 G/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.3 -5.95 -0.31 6.73e-9 Monocyte percentage of white cells; LIHC cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg12310025 chr6:25882481 NA 0.56 7.68 0.38 1.65e-13 Blood metabolite levels; LIHC cis rs9378688 0.654 rs11963138 chr6:2264559 A/C cg12303981 chr6:2244766 GMDS -0.43 -6.09 -0.31 3.04e-9 Caudate nucleus volume; LIHC cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.52 -8.02 -0.4 1.68e-14 Menarche (age at onset); LIHC cis rs3770081 1.000 rs77309268 chr2:86293294 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -8.49 -0.42 6.21e-16 Facial emotion recognition (sad faces); LIHC cis rs7613875 0.600 rs2856237 chr3:50158774 A/G cg24110177 chr3:50126178 RBM5 0.57 9.46 0.46 5.26e-19 Body mass index; LIHC cis rs780096 0.546 rs715326 chr2:27725761 A/G cg22903471 chr2:27725779 GCKR 0.52 9.37 0.45 9.85e-19 Total body bone mineral density; LIHC cis rs7584330 0.704 rs72620821 chr2:238362615 C/A cg14458575 chr2:238380390 NA 0.53 7.48 0.37 6.33e-13 Prostate cancer; LIHC cis rs8017423 0.872 rs7492857 chr14:90684867 T/G cg04374321 chr14:90722782 PSMC1 -0.75 -14.21 -0.61 2.43e-36 Mortality in heart failure; LIHC cis rs11608355 0.545 rs1073780 chr12:109895143 T/C cg05360138 chr12:110035743 NA 0.97 10.75 0.5 2.07e-23 Neuroticism; LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.570 rs951281 chr1:150691122 A/C cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs6545883 0.929 rs10190332 chr2:61619267 T/G cg14146966 chr2:61757674 XPO1 -0.44 -7.45 -0.37 7.93e-13 Tuberculosis; LIHC cis rs858239 0.601 rs10278700 chr7:23160529 T/C cg23682824 chr7:23144976 KLHL7 0.42 6.37 0.33 5.99e-10 Cerebrospinal fluid biomarker levels; LIHC trans rs1005277 0.540 rs116205409 chr10:38478970 G/A cg17830980 chr10:43048298 ZNF37B -0.52 -10.18 -0.48 2e-21 Extrinsic epigenetic age acceleration; LIHC trans rs9929218 1.000 rs12448448 chr16:68802516 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.78 -0.43 8.25e-17 Colorectal cancer; LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg02592271 chr2:27665507 KRTCAP3 -0.43 -6.0 -0.31 5.09e-9 Total body bone mineral density; LIHC cis rs9814567 1.000 rs1534025 chr3:134313304 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.13 0.55 2.04e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs116095464 0.558 rs1541822 chr5:269234 A/C cg22857025 chr5:266934 NA 1.52 18.78 0.71 1.37e-54 Breast cancer; LIHC cis rs12220238 1.000 rs11000924 chr10:75972311 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.54 0.33 2.25e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.12 -0.44 6.77e-18 Bipolar disorder; LIHC trans rs4906332 1.000 rs17617094 chr14:103893428 T/C cg17675199 chr6:35436792 RPL10A 0.31 6.22 0.32 1.49e-9 Coronary artery disease; LIHC cis rs9733 0.596 rs7549795 chr1:150656873 G/A cg15448220 chr1:150897856 SETDB1 0.39 6.14 0.32 2.31e-9 Tonsillectomy; LIHC cis rs9467773 1.000 rs9467782 chr6:26542773 G/A cg11502198 chr6:26597334 ABT1 0.4 5.84 0.3 1.24e-8 Intelligence (multi-trait analysis); LIHC trans rs2262909 0.962 rs1526884 chr19:22303651 A/G cg17074339 chr11:11642133 GALNTL4 0.47 7.32 0.37 1.78e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs67981189 0.593 rs8008111 chr14:71531246 G/C cg15816911 chr14:71606274 NA 0.43 6.89 0.35 2.63e-11 Schizophrenia; LIHC cis rs4478037 0.732 rs12490111 chr3:33103007 G/A cg27203090 chr3:33138513 GLB1;TMPPE -0.54 -6.17 -0.32 1.93e-9 Major depressive disorder; LIHC trans rs6489882 0.867 rs4766663 chr12:113362974 C/T cg10175203 chr3:128143634 NA -0.37 -6.11 -0.31 2.72e-9 Chronic lymphocytic leukemia; LIHC trans rs11689435 0.925 rs4555323 chr2:218352602 C/A cg13544946 chr9:35729779 TLN1 -0.45 -6.36 -0.33 6.42e-10 Metabolite levels (MHPG); LIHC trans rs61931739 0.500 rs11053217 chr12:34470036 A/C cg26384229 chr12:38710491 ALG10B 0.65 8.2 0.41 4.79e-15 Morning vs. evening chronotype; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00050938 chr3:50296100 GNAI2 -0.41 -7.07 -0.36 8.78e-12 Lobe attachment (rater-scored or self-reported); LIHC trans rs2739330 0.789 rs5760109 chr22:24252938 C/G cg06437703 chr8:37914619 EIF4EBP1 -0.52 -7.85 -0.39 5.46e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1185460 0.904 rs1003081 chr11:118913993 A/G cg23280166 chr11:118938394 VPS11 -0.47 -6.62 -0.34 1.38e-10 Coronary artery disease; LIHC cis rs970821 0.667 rs11774647 chr8:124743895 T/C cg00283535 chr8:124749564 ANXA13 0.42 7.52 0.38 4.93e-13 Breast cancer; LIHC cis rs6684514 1.000 rs12023438 chr1:156254358 A/G cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs36051895 0.589 rs1322222 chr9:5190444 A/G cg02405213 chr9:5042618 JAK2 -0.69 -11.65 -0.53 1.23e-26 Pediatric autoimmune diseases; LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.18 -0.4 5.48e-15 Lymphocyte counts; LIHC cis rs919433 0.713 rs6719729 chr2:198480072 G/A cg03934865 chr2:198174659 NA 0.49 7.5 0.38 5.42e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs34779708 0.966 rs2045915 chr10:35418616 G/C cg03585969 chr10:35415529 CREM 0.8 11.88 0.54 1.7e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9473924 0.580 rs68118663 chr6:50815367 C/T cg14470998 chr6:50812995 TFAP2B 0.93 10.62 0.5 6.08e-23 Body mass index; LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7312774 0.748 rs1861746 chr12:107301518 G/A cg16260113 chr12:107380972 MTERFD3 0.78 10.23 0.48 1.3e-21 Severe influenza A (H1N1) infection; LIHC cis rs17685 0.784 rs1637043 chr7:75699099 G/A cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7208859 0.623 rs77544470 chr17:28934550 C/A cg14067834 chr17:29058358 SUZ12P 0.66 6.45 0.33 3.75e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7577696 0.568 rs7562653 chr2:32478629 T/C cg02381751 chr2:32503542 YIPF4 0.48 6.65 0.34 1.17e-10 Inflammatory biomarkers; LIHC cis rs765787 0.530 rs2413786 chr15:45525394 C/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.05e-13 Uric acid levels; LIHC cis rs34375054 0.624 rs12826658 chr12:125680237 A/G cg25124228 chr12:125621409 AACS -0.44 -7.38 -0.37 1.19e-12 Post bronchodilator FEV1/FVC ratio; LIHC cis rs11229555 0.645 rs12785578 chr11:58206432 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs10751667 0.666 rs11246357 chr11:963980 A/C cg10932868 chr11:921992 NA 0.39 7.38 0.37 1.22e-12 Alzheimer's disease (late onset); LIHC cis rs9649213 0.727 rs12113294 chr7:97910637 C/G cg09267113 chr7:98030324 BAIAP2L1 0.43 7.91 0.39 3.6e-14 Prostate cancer (SNP x SNP interaction); LIHC cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg06238570 chr21:40685208 BRWD1 0.58 6.79 0.34 5.07e-11 Cognitive function; LIHC cis rs7208859 0.623 rs11657777 chr17:29091785 T/C cg14067834 chr17:29058358 SUZ12P 0.69 6.86 0.35 3.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17376456 0.569 rs2045019 chr5:93201971 C/T cg25358565 chr5:93447407 FAM172A -0.8 -7.7 -0.38 1.47e-13 Diabetic retinopathy; LIHC trans rs4906332 0.966 rs12185021 chr14:103927805 A/G cg17675199 chr6:35436792 RPL10A 0.34 6.63 0.34 1.32e-10 Coronary artery disease; LIHC cis rs11997175 0.646 rs55898196 chr8:33765862 A/G ch.8.33884649F chr8:33765107 NA 0.33 5.89 0.3 9.24e-9 Body mass index; LIHC cis rs919433 0.680 rs6434934 chr2:198437386 C/G cg10820045 chr2:198174542 NA 0.51 8.2 0.41 4.84e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7945718 0.621 rs10831888 chr11:12665604 T/C cg25843174 chr11:12811716 TEAD1 0.33 7.67 0.38 1.75e-13 Educational attainment (years of education); LIHC cis rs7578199 0.962 rs11680329 chr2:242186837 C/T cg19372975 chr2:242212901 HDLBP -0.6 -5.78 -0.3 1.72e-8 Chronic lymphocytic leukemia; LIHC cis rs10791323 0.582 rs2851120 chr11:133708065 A/G cg06766960 chr11:133703094 NA -0.64 -10.73 -0.5 2.42e-23 Childhood ear infection; LIHC trans rs2727020 0.553 rs3862350 chr11:49595912 A/C cg18944383 chr4:111397179 ENPEP 0.25 6.15 0.32 2.21e-9 Coronary artery disease; LIHC cis rs7542091 0.704 rs2142907 chr1:210039505 T/C cg23283495 chr1:209979779 IRF6 0.35 5.99 0.31 5.17e-9 Monobrow; LIHC cis rs2239815 0.515 rs12170231 chr22:29237824 C/T cg15103426 chr22:29168792 CCDC117 0.43 5.81 0.3 1.45e-8 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02136628 chr17:41476456 ARL4D -0.52 -6.18 -0.32 1.79e-9 Systolic blood pressure; LIHC cis rs3736594 0.513 rs78170284 chr2:27835082 G/A cg27432699 chr2:27873401 GPN1 0.46 6.76 0.34 5.84e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs4689642 0.666 rs4689659 chr4:7228214 C/T cg21353189 chr4:7228343 SORCS2 0.36 6.22 0.32 1.49e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs763014 0.966 rs4984904 chr16:680809 C/G cg04709771 chr16:646395 RAB40C 0.47 8.3 0.41 2.44e-15 Height; LIHC trans rs1814175 0.817 rs1996982 chr11:49972619 G/T cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs875971 0.862 rs778702 chr7:65864835 G/A cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs74181299 0.684 rs17040050 chr2:65327042 G/A cg05010058 chr2:65284262 CEP68 -0.4 -6.71 -0.34 8.22e-11 Pulse pressure; LIHC cis rs644799 1.000 rs1944074 chr11:95511445 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.91 0.47 1.6e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs67311347 0.955 rs11719205 chr3:40417258 G/A cg00656387 chr3:40428638 ENTPD3 0.42 6.9 0.35 2.6e-11 Renal cell carcinoma; LIHC cis rs8017423 0.935 rs4904661 chr14:90729332 T/C cg14092571 chr14:90743983 NA -0.42 -6.72 -0.34 7.72e-11 Mortality in heart failure; LIHC cis rs748404 0.690 rs1079309 chr15:43783164 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.34 0.37 1.61e-12 Lung cancer; LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.52 7.6 0.38 2.88e-13 Height; LIHC cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg10862848 chr6:42927986 GNMT -0.24 -5.86 -0.3 1.1e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2380220 0.576 rs4498363 chr6:96042338 A/C cg15832292 chr6:96025679 MANEA 0.7 8.72 0.43 1.21e-16 Behavioural disinhibition (generation interaction); LIHC cis rs7824557 0.603 rs6995404 chr8:11182148 C/G cg21775007 chr8:11205619 TDH 0.61 10.33 0.49 6.17e-22 Retinal vascular caliber; LIHC cis rs6570726 0.791 rs9390336 chr6:145896823 A/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.36 -0.33 6.55e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.36 0.45 1.11e-18 Bipolar disorder; LIHC cis rs1707322 0.691 rs28495425 chr1:46187320 T/G cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg25894440 chr7:65020034 NA 0.54 6.22 0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs9640161 0.789 rs3735172 chr7:150028958 C/T cg21361702 chr7:150065534 REPIN1 -0.45 -6.08 -0.31 3.26e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs35110281 0.627 rs7283362 chr21:44973667 C/G cg21573476 chr21:45109991 RRP1B -0.49 -9.12 -0.44 6.71e-18 Mean corpuscular volume; LIHC trans rs2270927 0.790 rs4613682 chr5:75576455 G/C cg13563193 chr19:33072644 PDCD5 0.87 9.63 0.46 1.44e-19 Mean corpuscular volume; LIHC cis rs6456156 0.586 rs7761977 chr6:167485678 A/G cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.07e-9 Primary biliary cholangitis; LIHC cis rs7312774 0.618 rs12316286 chr12:107343020 C/A cg16260113 chr12:107380972 MTERFD3 0.85 11.16 0.52 7.43e-25 Severe influenza A (H1N1) infection; LIHC trans rs1997066 0.920 rs58578339 chr10:106726669 A/C cg21239439 chr6:170038665 WDR27 0.67 6.08 0.31 3.23e-9 Diabetic kidney disease; LIHC cis rs763121 0.853 rs7289855 chr22:39042221 G/T cg06022373 chr22:39101656 GTPBP1 0.67 11.5 0.53 4.19e-26 Menopause (age at onset); LIHC cis rs743757 1.000 rs2236964 chr3:50449062 C/G cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.5 -7.79 -0.39 8.06e-14 Diastolic blood pressure; LIHC cis rs7131987 0.903 rs67517901 chr12:29421346 A/G cg14222432 chr12:29376421 FAR2 0.37 7.13 0.36 5.83e-12 QT interval; LIHC cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg12292205 chr6:26970375 C6orf41 0.34 5.83 0.3 1.27e-8 Intelligence (multi-trait analysis); LIHC cis rs801193 1.000 rs2707845 chr7:66198798 C/T cg18876405 chr7:65276391 NA 0.42 7.29 0.37 2.17e-12 Aortic root size; LIHC trans rs13381277 1.000 rs937898 chr18:74330672 C/G cg17352830 chr21:37617589 DOPEY2 0.56 6.63 0.34 1.33e-10 Dental caries; LIHC cis rs1048257 0.682 rs2582514 chr14:105413204 G/T cg21017887 chr14:105400489 NA 0.67 12.39 0.56 2.21e-29 Systemic lupus erythematosus; LIHC trans rs1941687 0.509 rs7230319 chr18:31321289 A/T cg27147174 chr7:100797783 AP1S1 -0.46 -6.32 -0.32 8.1e-10 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs9814567 1.000 rs9289471 chr3:134230811 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.66 -12.15 -0.55 1.77e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2404602 0.552 rs11630185 chr15:76959783 A/T cg23625390 chr15:77176239 SCAPER -0.46 -7.27 -0.37 2.47e-12 Blood metabolite levels; LIHC cis rs7216064 1.000 rs60432293 chr17:65860407 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs17854409 0.803 rs3210314 chr20:61472117 C/A cg06598544 chr20:61472147 COL9A3 -0.9 -8.42 -0.41 1.07e-15 Obesity-related traits; LIHC cis rs2439831 0.867 rs2243434 chr15:43689867 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 16.14 0.66 5.71e-44 Lung cancer in ever smokers; LIHC cis rs1395 1.000 rs1275501 chr2:27419282 A/C cg23587288 chr2:27483067 SLC30A3 0.31 6.05 0.31 3.75e-9 Blood metabolite levels; LIHC cis rs2842992 0.789 rs2842969 chr6:160145364 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.54 9.54 0.46 2.71e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs36051895 0.632 rs7850425 chr9:5170645 G/T cg02405213 chr9:5042618 JAK2 -0.68 -10.39 -0.49 3.83e-22 Pediatric autoimmune diseases; LIHC cis rs4332037 0.754 rs62436669 chr7:1926636 G/A cg23422044 chr7:1970798 MAD1L1 -0.65 -7.38 -0.37 1.25e-12 Bipolar disorder; LIHC cis rs12908161 0.920 rs35758837 chr15:85311382 C/T cg17507749 chr15:85114479 UBE2QP1 0.63 7.15 0.36 5.15e-12 Schizophrenia; LIHC cis rs9303401 0.614 rs3887355 chr17:56538639 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.39 0.52 1.05e-25 Cognitive test performance; LIHC cis rs12477438 0.520 rs6542869 chr2:99783403 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.35 0.59 5.07e-33 Chronic sinus infection; LIHC cis rs7647973 1.000 rs56127630 chr3:49438036 C/G cg07636037 chr3:49044803 WDR6 -0.53 -6.44 -0.33 4.07e-10 Menarche (age at onset); LIHC cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg06453172 chr10:134556979 INPP5A -0.64 -8.03 -0.4 1.58e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6754311 0.731 rs7579771 chr2:136580260 T/A cg25344623 chr2:136566232 LCT -0.41 -8.45 -0.42 8.52e-16 Mosquito bite size; LIHC cis rs3812831 0.661 rs2987458 chr13:114919835 A/G cg08824895 chr13:115047677 UPF3A 0.48 6.89 0.35 2.7e-11 Schizophrenia; LIHC cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg00343986 chr7:65444356 GUSB 0.44 6.22 0.32 1.43e-9 Calcium levels; LIHC cis rs4638749 0.677 rs12329189 chr2:108812855 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -5.96 -0.31 6.18e-9 Blood pressure; LIHC cis rs6088590 1.000 rs6119512 chr20:33306904 T/C cg08999081 chr20:33150536 PIGU 0.37 5.73 0.3 2.23e-8 Coronary artery disease; LIHC cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.8 7.86 0.39 5.07e-14 Platelet count; LIHC cis rs6088580 0.634 rs6059896 chr20:33111783 T/C cg08999081 chr20:33150536 PIGU 0.68 13.42 0.59 2.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg21448741 chr8:58168803 NA 0.34 6.14 0.32 2.31e-9 Developmental language disorder (linguistic errors); LIHC cis rs9296092 0.560 rs7765393 chr6:33525598 A/T cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7674212 0.539 rs6815783 chr4:104122146 A/C cg16532752 chr4:104119610 CENPE -0.45 -6.98 -0.35 1.55e-11 Type 2 diabetes; LIHC cis rs6748734 1.000 rs4293565 chr2:241834770 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -8.19 -0.4 5.3e-15 Urinary metabolites; LIHC cis rs1997103 1.000 rs7779040 chr7:55412947 T/C cg17469321 chr7:55412551 NA 0.49 7.19 0.36 3.98e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs509477 0.718 rs273363 chr18:32594703 A/G cg23791764 chr18:32556832 MAPRE2 0.47 6.32 0.32 8.16e-10 Cerebrospinal fluid AB1-42 levels; LIHC cis rs2576037 0.796 rs2576034 chr18:44588548 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.49 -7.49 -0.38 5.9e-13 Personality dimensions; LIHC cis rs13118159 0.836 rs2276903 chr4:1343405 A/G cg13395646 chr4:1353034 KIAA1530 -0.39 -5.88 -0.3 9.51e-9 Longevity; LIHC cis rs72717009 0.825 rs12746613 chr1:161467042 A/G cg10431340 chr1:161279108 MPZ 0.66 5.88 0.3 9.54e-9 Rheumatoid arthritis; LIHC cis rs1065656 0.553 rs344357 chr16:1836255 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.46 -6.91 -0.35 2.43e-11 Insulin-like growth factors; LIHC cis rs11764590 0.694 rs3996323 chr7:2079428 G/T cg23422044 chr7:1970798 MAD1L1 -0.49 -7.54 -0.38 4.32e-13 Neuroticism; LIHC cis rs2243480 1.000 rs160643 chr7:65558222 C/T cg18252515 chr7:66147081 NA -1.16 -15.86 -0.65 7.8e-43 Diabetic kidney disease; LIHC trans rs2018683 1.000 rs740252 chr7:28997765 C/G cg19402173 chr7:128379420 CALU -0.44 -6.84 -0.35 3.57e-11 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs7208859 0.524 rs57670615 chr17:29069498 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2075371 0.637 rs13245165 chr7:133951492 A/T cg11752832 chr7:134001865 SLC35B4 0.48 6.07 0.31 3.45e-9 Mean platelet volume; LIHC cis rs6545883 0.801 rs778142 chr2:61681428 G/T cg14146966 chr2:61757674 XPO1 0.47 8.12 0.4 8.6e-15 Tuberculosis; LIHC cis rs2439831 0.681 rs540031 chr15:43608855 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.9 16.97 0.68 2.72e-47 Lung cancer in ever smokers; LIHC cis rs35146811 0.807 rs10228764 chr7:99608029 A/G cg13334819 chr7:99746414 C7orf59 -0.56 -8.16 -0.4 6.59e-15 Coronary artery disease; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg18110333 chr6:292329 DUSP22 -0.54 -7.16 -0.36 5.04e-12 Menopause (age at onset); LIHC cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg03806693 chr22:41940476 POLR3H -1.1 -13.13 -0.58 3.72e-32 Vitiligo; LIHC cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs4407350 0.729 rs6007167 chr22:44888124 A/G cg11695653 chr22:44894386 LDOC1L -0.38 -6.48 -0.33 3.13e-10 Intelligence (multi-trait analysis); LIHC cis rs367615 0.918 rs10070104 chr5:108866438 C/T cg17395555 chr5:108820864 NA -0.35 -7.1 -0.36 7.06e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs66573146 0.831 rs56300156 chr4:6990813 G/C cg15105060 chr4:7024189 TBC1D14 -0.81 -6.47 -0.33 3.48e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7772486 0.875 rs1960885 chr6:146325930 G/T cg13319975 chr6:146136371 FBXO30 -0.35 -5.83 -0.3 1.28e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4746818 1.000 rs10823313 chr10:70952115 G/A cg11621586 chr10:70884670 VPS26A 0.84 13.55 0.59 8.5e-34 Left atrial antero-posterior diameter; LIHC cis rs8062405 1.000 rs61737565 chr16:28855522 G/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21653586 chr11:10530636 NA 0.47 6.04 0.31 3.92e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7772486 0.655 rs2142981 chr6:146071695 G/C cg23711669 chr6:146136114 FBXO30 -0.73 -13.51 -0.59 1.28e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs7980687 0.628 rs1727332 chr12:123718301 C/T cg00376283 chr12:123451042 ABCB9 0.69 10.52 0.49 1.36e-22 Height;Educational attainment;Head circumference (infant); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21638374 chr5:147763491 FBXO38 0.47 6.58 0.34 1.74e-10 Lung function (FEV1/FVC); LIHC cis rs317689 0.718 rs315130 chr12:69761444 T/C cg14784868 chr12:69753453 YEATS4 0.66 9.98 0.48 9.17e-21 Response to diuretic therapy; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg02592271 chr2:27665507 KRTCAP3 -0.46 -6.29 -0.32 9.64e-10 Total body bone mineral density; LIHC cis rs11190604 0.943 rs11190568 chr10:102224277 C/T cg07080220 chr10:102295463 HIF1AN 0.49 6.66 0.34 1.12e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17106184 1.000 rs12068606 chr1:51351281 C/T cg07174182 chr1:51127561 FAF1 -0.58 -6.53 -0.33 2.34e-10 Type 2 diabetes; LIHC cis rs1790761 0.607 rs656652 chr11:67343957 C/T cg01069141 chr11:67398826 TBX10;NUDT8 0.38 6.7 0.34 8.77e-11 Mean corpuscular volume; LIHC cis rs807029 0.758 rs807027 chr10:102764607 T/A cg27255678 chr10:102756921 LZTS2 0.43 5.88 0.3 9.66e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7729447 0.813 rs1031648 chr5:32692105 T/A cg16267343 chr5:32710456 NPR3 0.47 5.76 0.3 1.88e-8 Blood pressure; LIHC cis rs9467773 0.506 rs9393709 chr6:26365147 C/T cg09904177 chr6:26538194 HMGN4 -0.37 -5.79 -0.3 1.57e-8 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.862 rs4721167 chr7:1933224 C/T cg14004847 chr7:1930337 MAD1L1 -0.5 -7.06 -0.36 9.13e-12 Bipolar disorder and schizophrenia; LIHC cis rs79149102 0.579 rs7179097 chr15:75279240 T/G cg15902774 chr15:75289873 SCAMP5 0.39 5.82 0.3 1.33e-8 Lung cancer; LIHC cis rs367615 0.506 rs1428932 chr5:108792479 A/G cg17395555 chr5:108820864 NA -0.33 -7.1 -0.36 7.05e-12 Colorectal cancer (SNP x SNP interaction); LIHC trans rs1945213 0.694 rs11227113 chr11:55828024 C/T cg03929089 chr4:120376271 NA 0.53 6.83 0.35 3.94e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs35306767 0.903 rs11253492 chr10:936873 T/C cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs6076065 0.748 rs6048781 chr20:23380027 T/C cg11657817 chr20:23433608 CST11 0.31 6.69 0.34 9.31e-11 Facial morphology (factor 15, philtrum width); LIHC trans rs9914544 0.545 rs9915343 chr17:18766494 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.8e-10 Educational attainment (years of education); LIHC cis rs2243480 0.803 rs13224048 chr7:65993766 G/A cg18252515 chr7:66147081 NA -1.34 -18.25 -0.7 1.9e-52 Diabetic kidney disease; LIHC cis rs7552167 0.925 rs11249021 chr1:24512881 G/T cg01960748 chr1:24522592 NA -0.59 -8.11 -0.4 8.91e-15 Psoriasis vulgaris; LIHC cis rs1005277 0.579 rs1780121 chr10:38529437 C/A cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.81 -0.3 1.42e-8 Extrinsic epigenetic age acceleration; LIHC cis rs739401 0.566 rs7931504 chr11:3026712 C/T cg25174290 chr11:3078921 CARS 0.6 9.02 0.44 1.39e-17 Longevity; LIHC cis rs7238033 0.609 rs28898869 chr18:43315591 A/C cg20610511 chr18:43302872 SLC14A1 0.38 6.27 0.32 1.1e-9 Bladder cancer; LIHC cis rs1728785 0.901 rs12929568 chr16:68596689 A/G cg02972257 chr16:68554789 NA -0.51 -5.97 -0.31 6e-9 Ulcerative colitis; LIHC trans rs7618501 1.000 rs6446295 chr3:49809063 G/T cg21659725 chr3:3221576 CRBN 0.99 19.75 0.73 1.74e-58 Intelligence (multi-trait analysis); LIHC cis rs1757171 0.542 rs1757186 chr6:37484111 A/G cg01843034 chr6:37503916 NA -0.46 -7.99 -0.4 2.03e-14 Cognitive performance; LIHC cis rs769267 0.930 rs7256149 chr19:19566255 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.87 0.3 1.01e-8 Tonsillectomy; LIHC cis rs1538970 1.000 rs1417578 chr1:45850590 A/G cg05343316 chr1:45956843 TESK2 0.55 8.31 0.41 2.28e-15 Platelet count; LIHC cis rs6570726 0.577 rs406868 chr6:145809983 C/T cg13319975 chr6:146136371 FBXO30 -0.56 -8.89 -0.43 3.62e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs4820294 1.000 rs732856 chr22:38060691 C/G cg10587741 chr22:38071170 LGALS1 -0.73 -12.93 -0.57 2.03e-31 Fat distribution (HIV); LIHC cis rs875971 0.862 rs801203 chr7:66023012 A/G cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.28e-34 Aortic root size; LIHC cis rs2427308 0.643 rs477859 chr20:60937597 A/G cg06026331 chr20:60912101 LAMA5 -0.53 -6.44 -0.33 4e-10 Colorectal cancer; LIHC cis rs4903214 1.000 rs2024244 chr14:74710864 C/A cg11132536 chr14:74711944 VSX2 -0.27 -6.52 -0.33 2.56e-10 Inflammatory bowel disease; LIHC trans rs8002861 0.967 rs2325071 chr13:44476793 T/C cg17145862 chr1:211918768 LPGAT1 0.66 13.23 0.58 1.43e-32 Leprosy; LIHC cis rs12464483 0.591 rs2602775 chr2:30883012 C/T cg12454169 chr2:30669597 LCLAT1 0.43 5.79 0.3 1.56e-8 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs208520 0.690 rs1580430 chr6:66715162 T/A cg07460842 chr6:66804631 NA 0.78 9.02 0.44 1.35e-17 Exhaled nitric oxide output; LIHC cis rs9911578 1.000 rs9911578 chr17:56953147 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs1506636 1.000 rs635072 chr7:123403255 G/A cg03229431 chr7:123269106 ASB15 0.6 11.92 0.54 1.25e-27 Plateletcrit;Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02441305 chr17:42767179 CCDC43 -0.46 -6.31 -0.32 8.7e-10 Pancreatic cancer; LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg06420487 chr17:61919686 SMARCD2 0.45 6.22 0.32 1.43e-9 Height; LIHC cis rs6582630 0.519 rs11495373 chr12:38275470 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.22 0.48 1.39e-21 Drug-induced liver injury (flucloxacillin); LIHC cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg05555928 chr11:63887634 MACROD1 0.54 7.49 0.38 5.8e-13 Mean platelet volume; LIHC cis rs67478160 0.619 rs11623546 chr14:104269098 A/G cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs62458065 0.640 rs28587905 chr7:32533054 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.75 -7.29 -0.37 2.22e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs9287719 0.625 rs7567304 chr2:10790029 T/C cg02196655 chr2:10830764 NOL10 0.37 5.75 0.3 2.01e-8 Prostate cancer; LIHC cis rs3806843 0.648 rs702399 chr5:140024432 C/T cg19875535 chr5:140030758 IK -0.43 -6.96 -0.35 1.76e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs943466 0.955 rs3763253 chr6:33772761 C/T cg25922239 chr6:33757077 LEMD2 0.46 6.27 0.32 1.08e-9 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs6545883 0.894 rs6545845 chr2:61437044 G/C cg15711740 chr2:61764176 XPO1 0.43 5.91 0.3 8.1e-9 Tuberculosis; LIHC cis rs9911578 0.967 rs6503883 chr17:56917543 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.84 0.69 8.98e-51 Intelligence (multi-trait analysis); LIHC cis rs644799 0.622 rs1255167 chr11:95500213 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.71 11.83 0.54 2.7e-27 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9911578 0.842 rs12450766 chr17:56832965 G/C cg05425664 chr17:57184151 TRIM37 0.53 7.4 0.37 1.09e-12 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.930 rs34210004 chr17:41370337 A/T cg23758822 chr17:41437982 NA 0.9 16.36 0.66 7.78e-45 Menopause (age at onset); LIHC cis rs9486715 1.000 rs9386670 chr6:97060688 C/A cg18709589 chr6:96969512 KIAA0776 -0.44 -7.45 -0.37 7.53e-13 Headache; LIHC cis rs11588062 0.628 rs11211270 chr1:46838986 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.44 6.77 0.34 5.69e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs897984 0.520 rs12928081 chr16:30885159 T/G cg02466173 chr16:30829666 NA 0.44 6.64 0.34 1.2e-10 Dementia with Lewy bodies; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04132851 chr1:85155548 SSX2IP 0.49 6.71 0.34 8.2e-11 Pancreatic cancer; LIHC cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.6e-18 Bipolar disorder; LIHC cis rs3770081 0.590 rs79771503 chr2:86466739 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.74 -7.32 -0.37 1.79e-12 Facial emotion recognition (sad faces); LIHC cis rs9814567 1.000 rs7433991 chr3:134312292 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.0 -0.54 6.29e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1728785 0.901 rs1728797 chr16:68570989 A/T cg02972257 chr16:68554789 NA -0.56 -6.49 -0.33 2.93e-10 Ulcerative colitis; LIHC cis rs7647973 0.588 rs62262675 chr3:49673662 A/G cg03060546 chr3:49711283 APEH -0.56 -6.05 -0.31 3.89e-9 Menarche (age at onset); LIHC cis rs8114671 0.527 rs2295352 chr20:33320055 C/G cg24642439 chr20:33292090 TP53INP2 -0.41 -5.72 -0.3 2.33e-8 Height; LIHC cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs9399137 0.507 rs11757723 chr6:135291293 C/T cg24558204 chr6:135376177 HBS1L 0.6 10.23 0.48 1.34e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs870825 0.929 rs72689266 chr4:185591053 T/C cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs7927592 0.763 rs2513277 chr11:68360887 T/G cg01657329 chr11:68192670 LRP5 -0.5 -7.39 -0.37 1.14e-12 Total body bone mineral density; LIHC cis rs611744 0.870 rs685358 chr8:109161413 T/C cg21045802 chr8:109455806 TTC35 0.57 9.86 0.47 2.31e-20 Dupuytren's disease; LIHC trans rs1728785 1.000 rs7118 chr16:68600855 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.21 0.32 1.53e-9 Ulcerative colitis; LIHC cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg03517284 chr6:25882590 NA -0.62 -8.77 -0.43 8.61e-17 Blood metabolite levels; LIHC cis rs2637266 0.783 rs12258504 chr10:78477055 C/T cg18941641 chr10:78392320 NA 0.27 5.82 0.3 1.33e-8 Pulmonary function; LIHC cis rs10883723 0.810 rs2296581 chr10:104242886 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.23 0.55 8.75e-29 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9399137 0.561 rs11753985 chr6:135280438 C/T cg24558204 chr6:135376177 HBS1L 0.57 9.62 0.46 1.53e-19 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs17102423 0.594 rs1953232 chr14:65570386 A/C cg16583315 chr14:65563665 MAX 0.42 8.67 0.42 1.73e-16 Obesity-related traits; LIHC cis rs2832191 0.545 rs2251381 chr21:30530692 T/G cg24692254 chr21:30365293 RNF160 0.46 7.27 0.37 2.43e-12 Dental caries; LIHC cis rs6500602 0.727 rs2160567 chr16:4535557 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.46 7.11 0.36 6.93e-12 Schizophrenia; LIHC cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg19774624 chr17:42201019 HDAC5 0.66 9.82 0.47 3.18e-20 Total body bone mineral density; LIHC cis rs1355223 0.902 rs1258470 chr11:34729265 A/G cg11058730 chr11:34937778 PDHX;APIP 0.43 6.03 0.31 4.34e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11252926 0.625 rs7903876 chr10:482678 T/C cg09445902 chr10:555545 DIP2C 0.38 6.09 0.31 3.05e-9 Psychosis in Alzheimer's disease; LIHC cis rs1577917 0.771 rs2758844 chr6:86330115 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.86 -0.39 5.17e-14 Response to antipsychotic treatment; LIHC cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs73001065 0.636 rs11668104 chr19:19426181 G/A cg03709012 chr19:19516395 GATAD2A 0.76 8.11 0.4 9.02e-15 LDL cholesterol; LIHC cis rs7904368 0.754 rs7076955 chr10:16852781 G/A cg23933602 chr10:16859644 RSU1 0.58 5.79 0.3 1.58e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs7772486 0.875 rs2814863 chr6:146347299 C/T cg23711669 chr6:146136114 FBXO30 -0.59 -10.41 -0.49 3.14e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs941873 0.868 rs2181080 chr10:81121960 A/G cg11057378 chr10:81107060 PPIF 0.37 5.92 0.3 7.8e-9 Height; LIHC cis rs11212260 0.655 rs11212225 chr11:107296099 G/T cg25435332 chr11:107328525 CWF19L2 0.75 7.84 0.39 5.64e-14 IgG glycosylation; LIHC trans rs17685 0.672 rs56343450 chr7:75796235 C/T cg19862616 chr7:65841803 NCRNA00174 0.94 19.23 0.72 2.29e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1552244 0.554 rs6762702 chr3:10055789 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -8.0 -0.4 1.93e-14 Alzheimer's disease; LIHC cis rs9611519 0.732 rs1883826 chr22:41703428 G/A cg03806693 chr22:41940476 POLR3H -0.71 -8.44 -0.42 8.82e-16 Neuroticism; LIHC cis rs72781680 1.000 rs72781680 chr2:24238928 C/T cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg11899201 chr4:82391576 RASGEF1B -0.34 -6.6 -0.34 1.59e-10 Oropharynx cancer; LIHC cis rs2070433 0.559 rs11089057 chr21:47721228 T/A cg12379764 chr21:47803548 PCNT 0.7 7.92 0.39 3.33e-14 Lymphocyte counts; LIHC cis rs4660306 0.744 rs11211113 chr1:45923668 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC 0.65 6.97 0.35 1.67e-11 Homocysteine levels; LIHC cis rs2204008 0.542 rs34770471 chr12:38009613 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs16877106 1.000 rs73254140 chr4:25318393 G/C cg04796973 chr4:25314218 ZCCHC4 0.62 5.85 0.3 1.18e-8 Weight; LIHC cis rs600806 0.778 rs11101961 chr1:110008813 T/C cg02415029 chr1:110025642 ATXN7L2 -0.49 -6.31 -0.32 8.63e-10 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.791 rs10984997 chr9:123481206 T/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 8.16 0.4 6.56e-15 Hip circumference adjusted for BMI; LIHC cis rs1577917 0.958 rs34795473 chr6:86461799 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.35 -0.41 1.7e-15 Response to antipsychotic treatment; LIHC cis rs11792861 0.926 rs7870597 chr9:111871864 T/C cg13535736 chr9:111863775 C9orf5 -0.38 -5.73 -0.3 2.21e-8 Menarche (age at onset); LIHC trans rs2694917 0.669 rs813497 chr12:56924116 A/G cg15380473 chr2:11864427 NA -0.51 -6.26 -0.32 1.13e-9 Blood metabolite ratios; LIHC cis rs17125944 0.686 rs7145440 chr14:53333717 A/G cg00686598 chr14:53173677 PSMC6 -0.74 -8.63 -0.42 2.4e-16 Alzheimer's disease (late onset); LIHC cis rs8017423 0.900 rs11625870 chr14:90693396 C/T cg14092571 chr14:90743983 NA 0.4 6.27 0.32 1.06e-9 Mortality in heart failure; LIHC cis rs1552244 0.572 rs17032426 chr3:10167112 G/A cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs1538970 0.739 rs4660863 chr1:45955868 T/C cg24296786 chr1:45957014 TESK2 -0.51 -7.52 -0.38 4.86e-13 Platelet count; LIHC cis rs7552404 1.000 rs12126607 chr1:76217097 G/A cg03433033 chr1:76189801 ACADM 0.65 9.18 0.44 4.29e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg03264133 chr6:25882463 NA -0.68 -8.82 -0.43 6.12e-17 Intelligence (multi-trait analysis); LIHC cis rs11822910 0.724 rs7106223 chr11:57190448 A/G cg00522883 chr11:57194120 SLC43A3 -0.71 -8.5 -0.42 6.09e-16 Platelet distribution width; LIHC cis rs6088590 0.965 rs6119534 chr20:33441257 C/T cg06115741 chr20:33292138 TP53INP2 0.58 7.83 0.39 6e-14 Coronary artery disease; LIHC cis rs116248771 0.739 rs4334688 chr3:158358666 C/G cg16708174 chr3:158430962 RARRES1 0.48 6.42 0.33 4.44e-10 diarrhoeal disease at age 2; LIHC cis rs7044106 0.762 rs12003646 chr9:123470621 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.71 11.34 0.52 1.63e-25 Hip circumference adjusted for BMI; LIHC cis rs4423214 1.000 rs11600860 chr11:71164019 T/C cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg02990361 chr1:107599529 PRMT6 0.63 10.59 0.5 7.44e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs713477 0.967 rs7146170 chr14:55914054 G/C cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.45e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs7618501 1.000 rs9872864 chr3:49792023 A/G cg24110177 chr3:50126178 RBM5 0.42 6.49 0.33 3.1e-10 Intelligence (multi-trait analysis); LIHC cis rs4147929 0.625 rs4147934 chr19:1065018 G/T cg05372495 chr19:1063624 ABCA7 -0.42 -6.66 -0.34 1.1e-10 Alzheimer's disease (late onset); LIHC cis rs7927592 0.913 rs948316 chr11:68309670 G/T cg16797656 chr11:68205561 LRP5 0.51 8.11 0.4 9.12e-15 Total body bone mineral density; LIHC cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.08 11.64 0.53 1.34e-26 Platelet count; LIHC cis rs651907 0.557 rs7629753 chr3:101371922 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.72 -12.89 -0.57 2.96e-31 Colorectal cancer; LIHC cis rs4862307 0.836 rs6829678 chr4:185001631 C/T cg06737308 chr4:185021514 ENPP6 -0.42 -6.35 -0.32 6.88e-10 Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs1790761 0.692 rs614080 chr11:67347287 G/A cg01069141 chr11:67398826 TBX10;NUDT8 0.37 6.57 0.33 1.85e-10 Mean corpuscular volume; LIHC cis rs7551222 0.691 rs11240760 chr1:204547268 A/G cg20240347 chr1:204465584 NA -0.35 -7.18 -0.36 4.42e-12 Schizophrenia; LIHC cis rs1639906 1.000 rs1637759 chr7:2220053 C/T cg18044113 chr7:2236405 MAD1L1 -0.36 -5.76 -0.3 1.88e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.2e-8 Vitiligo; LIHC cis rs4908768 0.906 rs28422051 chr1:8618337 T/C cg20416874 chr1:8611966 RERE 0.57 8.88 0.43 3.81e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg02931644 chr1:25747376 RHCE 0.35 7.63 0.38 2.28e-13 Erythrocyte sedimentation rate; LIHC cis rs1005277 0.602 rs1740743 chr10:38519222 C/T cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs7131987 0.903 rs6487796 chr12:29422764 A/G cg16970926 chr12:29381810 FAR2 0.28 5.94 0.31 6.84e-9 QT interval; LIHC trans rs4650994 0.525 rs10913567 chr1:178511941 A/C cg05059571 chr16:84539110 KIAA1609 -0.45 -7.5 -0.38 5.39e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs4970988 0.556 rs2280078 chr1:150600181 C/T cg18016565 chr1:150552671 MCL1 -0.62 -12.91 -0.57 2.4e-31 Urate levels; LIHC cis rs9810089 0.843 rs834304 chr3:136111658 G/T cg21827317 chr3:136751795 NA 0.43 5.72 0.3 2.32e-8 Gestational age at birth (child effect); LIHC cis rs72627123 0.500 rs67852564 chr14:74559920 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.52 7.16 0.36 4.96e-12 Morning vs. evening chronotype; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00166327 chr13:73356072 PIBF1;DIS3 -0.47 -6.11 -0.31 2.68e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7618501 1.000 rs4855862 chr3:49748833 C/T cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC cis rs10493773 0.609 rs6689168 chr1:86174232 G/T cg17807903 chr1:86174739 ZNHIT6 -0.63 -12.45 -0.56 1.37e-29 Urate levels in overweight individuals; LIHC cis rs6088813 0.925 rs1540928 chr20:33961845 C/A cg14752227 chr20:34000481 UQCC -0.4 -5.8 -0.3 1.53e-8 Height; LIHC cis rs757110 0.834 rs1002226 chr11:17405617 C/T cg15432903 chr11:17409602 KCNJ11 0.66 10.41 0.49 3.24e-22 Type 2 diabetes; LIHC cis rs1997103 1.000 rs6593233 chr7:55406200 C/T cg17469321 chr7:55412551 NA -0.46 -6.83 -0.35 3.92e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg18306943 chr3:40428807 ENTPD3 0.42 7.32 0.37 1.8e-12 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02621907 chr5:93954419 ANKRD32;C5orf36 0.45 6.41 0.33 4.74e-10 Pancreatic cancer; LIHC cis rs2197308 0.565 rs4123923 chr12:37857684 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs12701220 0.553 rs9639882 chr7:1133731 G/A cg04025307 chr7:1156635 C7orf50 0.55 7.31 0.37 1.9e-12 Bronchopulmonary dysplasia; LIHC cis rs1577917 0.566 rs2842611 chr6:86302034 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.26 -0.41 3.22e-15 Response to antipsychotic treatment; LIHC cis rs1005277 0.579 rs2474608 chr10:38457109 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs926392 0.965 rs6124106 chr20:37693042 G/A cg16355469 chr20:37678765 NA 0.36 5.77 0.3 1.77e-8 Dialysis-related mortality; LIHC cis rs11864453 1.000 rs7201491 chr16:72034312 G/A cg01557791 chr16:72042693 DHODH -0.73 -11.62 -0.53 1.6e-26 Fibrinogen levels; LIHC cis rs8060686 0.641 rs2107369 chr16:68116018 A/C cg05110241 chr16:68378359 PRMT7 -0.51 -5.82 -0.3 1.38e-8 HDL cholesterol;Metabolic syndrome; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00954536 chr5:110427846 WDR36 0.41 6.28 0.32 1e-9 Calcium levels; LIHC cis rs2075371 0.932 rs1035328 chr7:133978419 T/C cg11752832 chr7:134001865 SLC35B4 0.52 7.73 0.39 1.24e-13 Mean platelet volume; LIHC cis rs6835098 1.000 rs1054496 chr4:174089080 A/G cg27433088 chr4:174089019 GALNT7 0.4 7.28 0.37 2.3e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs7107174 0.579 rs10793299 chr11:78018954 T/A cg02023728 chr11:77925099 USP35 0.52 9.96 0.47 1.13e-20 Testicular germ cell tumor; LIHC cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg27286337 chr10:134555280 INPP5A 0.92 12.64 0.56 2.52e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17818399 0.890 rs34752561 chr2:46850150 G/A cg02822958 chr2:46747628 ATP6V1E2 0.43 6.25 0.32 1.22e-9 Height; LIHC cis rs11630290 0.604 rs17775820 chr15:64168582 G/A cg12036633 chr15:63758958 NA -0.64 -5.78 -0.3 1.73e-8 Iris characteristics; LIHC cis rs2153535 0.542 rs6912740 chr6:8439959 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.45e-16 Motion sickness; LIHC cis rs6840360 0.615 rs12641441 chr4:152607623 A/G cg22705602 chr4:152727874 NA -0.33 -6.92 -0.35 2.19e-11 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.666 rs7103585 chr11:971166 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs875971 0.545 rs6460276 chr7:65647277 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.38 7.65 0.38 2.03e-13 Aortic root size; LIHC cis rs1046896 0.552 rs12602280 chr17:80805421 G/C cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.42 0.33 4.56e-10 Glycated hemoglobin levels; LIHC cis rs9640161 0.663 rs1916932 chr7:150021644 T/C cg21361702 chr7:150065534 REPIN1 0.46 6.24 0.32 1.31e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg16145915 chr7:1198662 ZFAND2A -0.37 -9.43 -0.45 6.63e-19 Longevity;Endometriosis; LIHC cis rs11792861 0.566 rs1003346 chr9:111815340 C/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.46 6.64 0.34 1.26e-10 Menarche (age at onset); LIHC cis rs5769765 0.773 rs9616208 chr22:50313359 G/A cg26441486 chr22:50317300 CRELD2 0.36 5.75 0.3 1.98e-8 Schizophrenia; LIHC cis rs1843834 1.000 rs1843834 chr2:225558042 A/G cg22455342 chr2:225449267 CUL3 0.44 6.02 0.31 4.48e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.57 9.62 0.46 1.47e-19 Bipolar disorder; LIHC cis rs875971 0.508 rs10242423 chr7:66059175 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.28 -5.72 -0.3 2.3e-8 Aortic root size; LIHC cis rs7267979 0.966 rs2257705 chr20:25264664 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC trans rs4843747 0.605 rs28399183 chr16:88107277 G/A cg09572067 chr16:29127029 RRN3P2 0.51 8.06 0.4 1.3e-14 Menopause (age at onset); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg22542420 chr17:43183176 NMT1 0.45 6.66 0.34 1.07e-10 Bilirubin levels; LIHC cis rs17818399 0.749 rs13000560 chr2:46790997 G/T cg02822958 chr2:46747628 ATP6V1E2 0.51 7.4 0.37 1.1e-12 Height; LIHC trans rs783540 0.835 rs783522 chr15:83280613 A/G cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.14 -0.32 2.27e-9 Schizophrenia; LIHC cis rs67478160 0.584 rs12433009 chr14:104196405 C/G cg01849466 chr14:104193079 ZFYVE21 -0.57 -10.16 -0.48 2.26e-21 Schizophrenia; LIHC cis rs36051895 0.632 rs1571438 chr9:5140313 A/C cg02405213 chr9:5042618 JAK2 -0.67 -11.75 -0.54 5.12e-27 Pediatric autoimmune diseases; LIHC cis rs6546550 0.901 rs6716937 chr2:70127229 G/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC trans rs12310956 0.515 rs1872745 chr12:33985987 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.69 0.34 9.11e-11 Morning vs. evening chronotype; LIHC cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs6502050 0.835 rs7502676 chr17:80093433 C/G cg11859384 chr17:80120422 CCDC57 -0.41 -5.72 -0.3 2.37e-8 Life satisfaction; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25940730 chr4:16228647 TAPT1;FLJ39653 -0.42 -6.3 -0.32 9.03e-10 Pancreatic cancer; LIHC cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg18357526 chr6:26021779 HIST1H4A 0.98 14.29 0.61 1.24e-36 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.661 rs10015965 chr4:120268237 A/G cg25214090 chr10:38739885 LOC399744 0.44 7.16 0.36 4.98e-12 Corneal astigmatism; LIHC cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg02034447 chr16:89574710 SPG7 0.47 7.19 0.36 3.99e-12 Multiple myeloma (IgH translocation); LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg22963979 chr7:1858916 MAD1L1 -0.44 -7.22 -0.36 3.49e-12 Bipolar disorder and schizophrenia; LIHC cis rs738321 0.762 rs4820321 chr22:38579569 T/A cg25457927 chr22:38595422 NA -0.39 -9.33 -0.45 1.36e-18 Breast cancer; LIHC cis rs8114671 0.869 rs6060199 chr20:33654773 A/G cg07148914 chr20:33460835 GGT7 -0.55 -8.29 -0.41 2.63e-15 Height; LIHC cis rs5758343 1 rs5758343 chr22:41816652 A/T cg06634786 chr22:41940651 POLR3H 0.81 8.62 0.42 2.59e-16 Allergic disease (asthma, hay fever or eczema); LIHC cis rs875971 0.508 rs10258739 chr7:66062935 A/T cg18876405 chr7:65276391 NA -0.4 -7.33 -0.37 1.69e-12 Aortic root size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07699235 chr13:39260309 FREM2 0.39 6.14 0.32 2.29e-9 Cognitive function; LIHC cis rs7582180 0.627 rs2099611 chr2:101021090 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.22 0.41 4.31e-15 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg17554472 chr22:41940697 POLR3H -0.51 -5.72 -0.3 2.37e-8 Vitiligo; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17675882 chr20:35374068 NDRG3 0.42 6.71 0.34 7.97e-11 Cognitive function; LIHC cis rs11031096 0.655 rs12293706 chr11:4211581 C/G cg18678763 chr11:4115507 RRM1 -0.41 -5.92 -0.3 7.73e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs12310956 0.510 rs10772109 chr12:33839548 A/C cg06792154 chr17:29157990 ATAD5 0.4 6.34 0.32 7.11e-10 Morning vs. evening chronotype; LIHC cis rs12477438 0.798 rs6705821 chr2:99602832 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.71 -0.65 3.04e-42 Chronic sinus infection; LIHC cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2991971 0.810 rs2356413 chr1:45914048 A/T cg05343316 chr1:45956843 TESK2 0.45 6.59 0.34 1.62e-10 High light scatter reticulocyte count; LIHC cis rs2742417 0.603 rs2064062 chr3:45761115 G/C cg04837898 chr3:45731254 SACM1L -0.52 -8.67 -0.42 1.75e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs35110281 0.632 rs9306160 chr21:45107562 T/C cg04455712 chr21:45112962 RRP1B 0.54 9.17 0.44 4.44e-18 Mean corpuscular volume; LIHC cis rs7927771 1.000 rs11039412 chr11:47841581 G/A cg20307385 chr11:47447363 PSMC3 -0.44 -5.82 -0.3 1.36e-8 Subjective well-being; LIHC cis rs11098499 0.954 rs3733524 chr4:120423729 T/C cg09307838 chr4:120376055 NA 0.78 12.34 0.56 3.35e-29 Corneal astigmatism; LIHC cis rs1113500 0.965 rs10881495 chr1:108610986 C/A cg06207961 chr1:108661230 NA 0.36 6.94 0.35 2.03e-11 Growth-regulated protein alpha levels; LIHC trans rs7613875 0.620 rs7430334 chr3:50078221 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.58 -0.34 1.82e-10 Body mass index; LIHC trans rs9951602 0.512 rs8084836 chr18:76647841 A/G cg02800362 chr5:177631904 HNRNPAB 0.67 10.52 0.49 1.33e-22 Obesity-related traits; LIHC cis rs11758351 1.000 rs77957229 chr6:26185226 A/G cg03854865 chr6:26224070 HIST1H3E 0.7 7.73 0.39 1.17e-13 Gout;Renal underexcretion gout; LIHC cis rs6754311 0.512 rs12998387 chr2:136507039 A/G cg07305463 chr2:136567211 LCT 0.39 7.32 0.37 1.79e-12 Mosquito bite size; LIHC cis rs4423214 0.879 rs736894 chr11:71152258 A/G cg24826892 chr11:71159390 DHCR7 0.45 5.78 0.3 1.72e-8 Vitamin D levels; LIHC cis rs986417 0.892 rs55695351 chr14:60796565 G/T cg27398547 chr14:60952738 C14orf39 -0.72 -7.37 -0.37 1.29e-12 Gut microbiota (bacterial taxa); LIHC cis rs2737618 0.651 rs2816974 chr1:200082686 C/G cg21825944 chr1:200113062 NR5A2 0.46 7.86 0.39 5.05e-14 Uric acid levels; LIHC cis rs9733 0.818 rs4970926 chr1:150673684 T/C cg17724175 chr1:150552817 MCL1 -0.38 -7.84 -0.39 5.72e-14 Tonsillectomy; LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg03354898 chr7:1950403 MAD1L1 -0.36 -5.75 -0.3 1.94e-8 Bipolar disorder and schizophrenia; LIHC cis rs4900538 0.855 rs1190537 chr14:102887816 C/T cg18135206 chr14:102964638 TECPR2 -0.71 -11.02 -0.51 2.18e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg22963979 chr7:1858916 MAD1L1 0.43 7.2 0.36 3.9e-12 Bipolar disorder and schizophrenia; LIHC cis rs611744 0.967 rs627604 chr8:109189819 C/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs748404 0.650 rs556851 chr15:43571219 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.15 0.4 6.82e-15 Lung cancer; LIHC cis rs4727027 0.899 rs6944096 chr7:148870026 A/G cg23583168 chr7:148888333 NA -0.75 -10.73 -0.5 2.44e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs614226 1.000 rs616157 chr12:120925795 T/C cg01236616 chr12:121019343 POP5 -1.12 -11.47 -0.53 5.57e-26 Type 1 diabetes nephropathy; LIHC cis rs7618501 0.633 rs2252833 chr3:50004209 C/T cg21467203 chr3:49911342 NA -0.45 -8.11 -0.4 9.18e-15 Intelligence (multi-trait analysis); LIHC cis rs3106136 0.681 rs1609423 chr4:95301949 G/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg18305652 chr10:134549665 INPP5A 0.44 6.43 0.33 4.22e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs780096 0.814 rs780093 chr2:27742603 T/C cg22903471 chr2:27725779 GCKR -0.31 -5.91 -0.3 8.38e-9 Total body bone mineral density; LIHC cis rs950169 0.887 rs62029593 chr15:84955180 A/G cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.12e-11 Schizophrenia; LIHC cis rs7520050 0.581 rs3855959 chr1:46633874 C/T cg23431851 chr1:46668822 C1orf190;POMGNT1 0.47 7.36 0.37 1.38e-12 Red blood cell count;Reticulocyte count; LIHC trans rs875971 0.638 rs7793569 chr7:66116633 T/G cg26939375 chr7:64535504 NA -0.43 -6.82 -0.35 4.17e-11 Aortic root size; LIHC cis rs1008375 1.000 rs4698198 chr4:17656536 G/A cg04450456 chr4:17643702 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg10862848 chr6:42927986 GNMT -0.29 -6.86 -0.35 3.15e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs875971 0.862 rs10240949 chr7:65804417 A/G cg18252515 chr7:66147081 NA 0.44 6.34 0.32 7.48e-10 Aortic root size; LIHC cis rs1144333 0.655 rs1144337 chr1:76278877 A/G cg03433033 chr1:76189801 ACADM -0.55 -8.54 -0.42 4.34e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs4689592 0.554 rs3951346 chr4:7073321 C/T cg19539972 chr4:7069911 GRPEL1 0.68 10.02 0.48 7.06e-21 Monocyte percentage of white cells; LIHC cis rs875971 1.000 rs1544549 chr7:66090663 T/A cg11764359 chr7:65958608 NA -0.85 -15.0 -0.63 2e-39 Aortic root size; LIHC cis rs34172651 0.517 rs2287783 chr16:24831727 C/T cg00152838 chr16:24741724 TNRC6A -0.54 -6.56 -0.33 1.96e-10 Intelligence (multi-trait analysis); LIHC cis rs7937682 0.847 rs500163 chr11:111462649 T/G cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs694739 1.000 rs499425 chr11:64105929 A/G cg02228329 chr11:64053129 BAD;GPR137 -0.7 -10.26 -0.49 1.04e-21 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs6723226 0.699 rs805830 chr2:32501475 T/C cg02381751 chr2:32503542 YIPF4 0.74 11.1 0.51 1.15e-24 Intelligence (multi-trait analysis); LIHC cis rs1144333 1.000 rs60144605 chr1:76359699 A/C cg22875332 chr1:76189707 ACADM 0.4 6.33 0.32 7.88e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg22907277 chr7:1156413 C7orf50 0.59 8.97 0.44 1.94e-17 Longevity;Endometriosis; LIHC cis rs16912285 0.535 rs6484040 chr11:24309809 C/A ch.11.24196551F chr11:24239977 NA 0.8 10.91 0.51 5.6e-24 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs637571 0.522 rs3016868 chr11:65764383 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.25 0.45 2.46e-18 Eosinophil percentage of white cells; LIHC cis rs922107 0.846 rs359925 chr1:89996336 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.42 -0.37 9.38e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs9393692 0.905 rs9357004 chr6:26303319 A/G cg00631329 chr6:26305371 NA -0.43 -7.39 -0.37 1.14e-12 Educational attainment; LIHC cis rs34779708 0.931 rs7897457 chr10:35386040 A/G cg03585969 chr10:35415529 CREM 0.85 12.94 0.57 1.93e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7927592 0.673 rs2510392 chr11:68394457 C/G cg16797656 chr11:68205561 LRP5 0.49 8.44 0.42 9.06e-16 Total body bone mineral density; LIHC cis rs4631830 0.747 rs745180 chr10:51504493 A/C cg16070123 chr10:51489643 NA 0.38 6.03 0.31 4.15e-9 Prostate-specific antigen levels; LIHC cis rs17152411 0.947 rs7079199 chr10:126590820 A/C cg07906193 chr10:126599966 NA 0.48 7.31 0.37 1.9e-12 Height; LIHC cis rs754466 0.651 rs11002317 chr10:79617648 G/A cg17075019 chr10:79541650 NA -0.76 -11.66 -0.53 1.11e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8062405 0.965 rs8049439 chr16:28837515 A/G cg00204512 chr16:28754710 NA 0.29 5.71 0.3 2.39e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs7939886 0.920 rs12417606 chr11:55750479 C/T cg15704280 chr7:45808275 SEPT13 0.64 6.11 0.31 2.72e-9 Myopia (pathological); LIHC cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 12.16 0.55 1.55e-28 Platelet count; LIHC cis rs3849570 0.732 rs11715625 chr3:81875938 A/T cg07356753 chr3:81810745 GBE1 -0.54 -8.58 -0.42 3.46e-16 Waist circumference;Body mass index; LIHC cis rs780096 0.587 rs6760828 chr2:27579231 T/C cg05484376 chr2:27715224 FNDC4 0.38 6.41 0.33 4.72e-10 Total body bone mineral density; LIHC cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg18357526 chr6:26021779 HIST1H4A 0.93 12.7 0.57 1.59e-30 Intelligence (multi-trait analysis); LIHC cis rs748404 0.578 rs478028 chr15:43610772 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.59 10.53 0.49 1.2e-22 Lung cancer; LIHC cis rs7191439 0.674 rs4782430 chr16:88792047 A/G cg02389323 chr16:88786976 FAM38A 0.79 8.5 0.42 5.76e-16 Plateletcrit; LIHC cis rs12079745 0.793 rs11806445 chr1:169219029 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.75 -6.98 -0.35 1.53e-11 QT interval; LIHC cis rs10744422 0.843 rs3896870 chr12:123333611 T/C cg07706471 chr12:123319906 HIP1R -0.62 -8.14 -0.4 7.53e-15 Schizophrenia; LIHC cis rs7666738 0.830 rs28622458 chr4:98916651 A/G cg05340658 chr4:99064831 C4orf37 0.64 11.65 0.53 1.25e-26 Colonoscopy-negative controls vs population controls; LIHC trans rs79976124 0.879 rs17511467 chr6:66627293 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.73 0.34 7.17e-11 Type 2 diabetes; LIHC cis rs4934494 0.768 rs12570813 chr10:91390731 C/T cg19698084 chr10:91461284 KIF20B -0.46 -6.29 -0.32 9.75e-10 Red blood cell count; LIHC cis rs12594515 0.548 rs12912226 chr15:45985708 T/G cg01629716 chr15:45996671 NA 0.54 6.17 0.32 1.98e-9 Waist circumference;Weight; LIHC cis rs2857078 0.654 rs9896789 chr17:42314567 C/T cg08499158 chr17:42289980 UBTF -0.49 -8.39 -0.41 1.31e-15 Red cell distribution width;Reticulocyte count; LIHC cis rs7726839 0.555 rs4541696 chr5:581053 A/G cg16447950 chr5:562315 NA -0.43 -8.33 -0.41 1.94e-15 Obesity-related traits; LIHC cis rs13217239 0.621 rs12527231 chr6:27001288 G/A cg18867708 chr6:26865862 GUSBL1 0.52 8.03 0.4 1.64e-14 Schizophrenia; LIHC cis rs1580019 0.523 rs9791770 chr7:32582252 C/A cg14728415 chr7:32535168 LSM5;AVL9 0.42 6.06 0.31 3.52e-9 Cognitive ability; LIHC cis rs2075371 0.897 rs12667905 chr7:134000812 A/C cg20476274 chr7:133979776 SLC35B4 0.71 9.51 0.46 3.52e-19 Mean platelet volume; LIHC cis rs1215050 0.740 rs783941 chr4:99008235 T/C cg05340658 chr4:99064831 C4orf37 -0.39 -5.93 -0.31 7.26e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs5753037 0.809 rs740041 chr22:30200099 A/G cg01021169 chr22:30184971 ASCC2 -0.35 -6.66 -0.34 1.08e-10 Type 1 diabetes; LIHC cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg20011983 chr2:74347215 NA -0.39 -5.77 -0.3 1.81e-8 Gestational age at birth (maternal effect); LIHC cis rs801193 0.569 rs3846973 chr7:66120035 T/C cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs507080 0.922 rs644498 chr11:118567486 T/C cg04173919 chr11:118528438 PHLDB1 0.36 6.68 0.34 9.53e-11 Serum metabolite levels; LIHC cis rs6684514 0.961 rs10908501 chr1:156285513 G/T cg16558208 chr1:156270281 VHLL 0.55 10.39 0.49 3.56e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs6701037 1.000 rs34493921 chr1:175122759 A/G cg17845761 chr1:175162550 KIAA0040 -0.37 -6.14 -0.31 2.35e-9 Alcohol dependence; LIHC cis rs7223966 1.000 rs8081612 chr17:61724695 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.6 -7.15 -0.36 5.35e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs999943 0.810 rs62407648 chr6:33622436 C/G cg14003231 chr6:33640908 ITPR3 0.43 7.29 0.37 2.12e-12 Obesity (extreme); LIHC cis rs1005277 0.579 rs2505257 chr10:38372664 A/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.73 -0.5 2.35e-23 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs11760633 0.747 rs11765289 chr7:1833097 C/G cg23422044 chr7:1970798 MAD1L1 -0.42 -6.24 -0.32 1.32e-9 Coronary artery disease; LIHC cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg05555928 chr11:63887634 MACROD1 0.55 7.54 0.38 4.38e-13 Attention deficit hyperactivity disorder; LIHC cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg22633049 chr21:46681294 NA 0.36 6.09 0.31 3e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1577917 1.000 rs10944163 chr6:86658693 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.11 -0.48 3.39e-21 Response to antipsychotic treatment; LIHC cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs6912958 0.703 rs9359748 chr6:88095500 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.4 8.03 0.4 1.55e-14 Monocyte percentage of white cells; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg26338869 chr17:61819248 STRADA -0.59 -8.72 -0.43 1.21e-16 Prudent dietary pattern; LIHC cis rs2842992 0.915 rs2842980 chr6:160100116 A/T cg19482086 chr6:160211437 TCP1;MRPL18 0.71 11.99 0.54 6.66e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs7635838 0.586 rs347617 chr3:11278211 C/T cg00170343 chr3:11313890 ATG7 0.57 9.19 0.45 3.88e-18 HDL cholesterol; LIHC trans rs35110281 0.713 rs1378079 chr21:45011187 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.23 0.32 1.36e-9 Mean corpuscular volume; LIHC cis rs1707322 0.721 rs10890333 chr1:46100322 T/C cg06784218 chr1:46089804 CCDC17 0.42 7.82 0.39 6.4e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6586163 0.872 rs7910825 chr10:90743341 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.53 -7.76 -0.39 9.9e-14 Chronic lymphocytic leukemia; LIHC cis rs875971 0.508 rs10253883 chr7:66061138 T/C cg18876405 chr7:65276391 NA -0.41 -7.38 -0.37 1.18e-12 Aortic root size; LIHC trans rs2243480 0.901 rs1701759 chr7:65470932 G/T cg10756647 chr7:56101905 PSPH 1.11 13.6 0.59 5.63e-34 Diabetic kidney disease; LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg05025164 chr4:1340916 KIAA1530 0.76 11.62 0.53 1.56e-26 Longevity; LIHC cis rs59698941 0.882 rs6871970 chr5:132189594 G/A cg02081065 chr5:132209139 LEAP2 0.27 6.11 0.31 2.69e-9 Apolipoprotein A-IV levels; LIHC cis rs72781680 0.821 rs111571980 chr2:24201695 C/G cg08917208 chr2:24149416 ATAD2B 0.62 6.25 0.32 1.25e-9 Lymphocyte counts; LIHC cis rs7542091 0.666 rs7537070 chr1:210043565 A/G cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs763121 0.752 rs5757222 chr22:39060473 C/T cg06022373 chr22:39101656 GTPBP1 0.66 11.49 0.53 4.72e-26 Menopause (age at onset); LIHC cis rs858239 0.600 rs13438179 chr7:23143851 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.99 0.35 1.47e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs3857067 0.806 rs7678054 chr4:95093855 A/G cg11021082 chr4:95130006 SMARCAD1 0.42 6.82 0.35 4.2e-11 QT interval; LIHC cis rs9381040 0.655 rs2294695 chr6:41036770 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.29 -0.32 9.7e-10 Alzheimer's disease (late onset); LIHC cis rs1707322 0.963 rs6429581 chr1:46319096 G/A cg06784218 chr1:46089804 CCDC17 0.38 6.63 0.34 1.33e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7100689 0.577 rs10749560 chr10:82092801 G/T cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27256523 chr13:48877460 RB1 0.45 6.05 0.31 3.76e-9 Lung function (FEV1/FVC); LIHC cis rs5769765 1.000 rs5770755 chr22:50280136 T/C cg26441486 chr22:50317300 CRELD2 -0.35 -6.12 -0.31 2.5e-9 Schizophrenia; LIHC cis rs17125944 0.686 rs7158555 chr14:53362006 G/A cg00686598 chr14:53173677 PSMC6 -0.79 -8.89 -0.43 3.49e-17 Alzheimer's disease (late onset); LIHC cis rs1371867 0.839 rs1788186 chr8:101335686 T/C cg06636551 chr8:101224915 SPAG1 -0.47 -8.72 -0.43 1.26e-16 Atrioventricular conduction; LIHC cis rs921968 0.643 rs589967 chr2:219445165 T/C cg18887096 chr2:219472410 PLCD4 0.36 6.32 0.32 8.27e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1801251 0.778 rs812383 chr2:233737132 C/A cg08000102 chr2:233561755 GIGYF2 -0.72 -10.72 -0.5 2.69e-23 Coronary artery disease; LIHC cis rs763121 0.853 rs6519124 chr22:39045099 T/C cg06022373 chr22:39101656 GTPBP1 0.75 15.23 0.64 2.5e-40 Menopause (age at onset); LIHC cis rs2274273 0.875 rs2075602 chr14:55609774 A/G cg04306507 chr14:55594613 LGALS3 0.33 6.36 0.33 6.32e-10 Protein biomarker; LIHC cis rs11763147 1 rs11763147 chr7:65326821 C/T cg14393609 chr7:65229607 NA -0.44 -6.49 -0.33 3.1e-10 Corneal structure; LIHC cis rs9303280 0.806 rs12232497 chr17:38040119 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.83 0.3 1.29e-8 Self-reported allergy; LIHC cis rs79057730 0.527 rs34519158 chr7:811114 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.85 9.65 0.46 1.23e-19 Initial pursuit acceleration; LIHC cis rs9640161 0.830 rs35840727 chr7:150063204 A/G cg10018233 chr7:150070692 REPIN1 0.69 12.4 0.56 2.04e-29 Blood protein levels;Circulating chemerin levels; LIHC cis rs4820294 1.000 rs62236667 chr22:38061520 C/G cg26138144 chr22:38071188 LGALS1 0.75 14.21 0.61 2.53e-36 Fat distribution (HIV); LIHC cis rs2404602 0.647 rs4886837 chr15:77156417 A/G cg03037974 chr15:76606532 NA -0.59 -10.09 -0.48 4.02e-21 Blood metabolite levels; LIHC trans rs9914544 0.524 rs8071147 chr17:18790678 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.57 -0.33 1.82e-10 Educational attainment (years of education); LIHC cis rs894734 0.535 rs2366142 chr12:54323148 T/C cg12374095 chr12:54320830 NA 0.45 6.98 0.35 1.57e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs72781680 1.000 rs72781675 chr2:24232092 G/A cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs9560113 0.960 rs9560101 chr13:112173798 G/A cg14154082 chr13:112174009 NA 0.29 6.1 0.31 2.81e-9 Menarche (age at onset); LIHC cis rs7917772 0.560 rs11595170 chr10:104339851 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.59 -0.38 3.04e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs61712019 0.679 rs2861054 chr2:77716564 A/C cg11252801 chr2:77748917 LRRTM4 0.56 7.73 0.39 1.2e-13 Schizophrenia; LIHC cis rs780096 0.545 rs11695549 chr2:27586155 A/C cg21747090 chr2:27597821 SNX17 -0.43 -6.28 -0.32 1.01e-9 Total body bone mineral density; LIHC cis rs16944613 0.636 rs6416552 chr15:91132111 T/C cg26821196 chr15:91095069 CRTC3 0.44 7.53 0.38 4.6e-13 Colorectal cancer; LIHC trans rs7226229 0.950 rs2291037 chr17:20924523 C/T cg20684973 chr10:105127632 TAF5 -0.45 -6.16 -0.32 2.08e-9 Blood trace element (Se levels); LIHC cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.85 0.35 3.42e-11 Gut microbiome composition (summer); LIHC cis rs4908760 0.539 rs2185205 chr1:8882664 T/A cg20416874 chr1:8611966 RERE -0.51 -8.88 -0.43 3.94e-17 Vitiligo; LIHC cis rs6754311 0.593 rs10202489 chr2:136494186 G/A cg07305463 chr2:136567211 LCT 0.39 7.07 0.36 8.54e-12 Mosquito bite size; LIHC trans rs1973993 0.691 rs2985636 chr1:96889884 T/A cg10631902 chr5:14652156 NA 0.36 9.74 0.47 5.88e-20 Weight; LIHC cis rs6500602 0.647 rs4786519 chr16:4584406 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 5.82 0.3 1.35e-8 Schizophrenia; LIHC cis rs240764 0.621 rs6925840 chr6:101209386 C/T cg09795085 chr6:101329169 ASCC3 -0.56 -8.09 -0.4 1.09e-14 Neuroticism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06268701 chr1:110091083 GNAI3 -0.45 -6.08 -0.31 3.23e-9 Pancreatic cancer; LIHC cis rs10751667 0.600 rs7395387 chr11:1008664 G/C ch.11.42038R chr11:967971 AP2A2 0.58 10.71 0.5 2.85e-23 Alzheimer's disease (late onset); LIHC cis rs459571 0.959 rs416390 chr9:136908549 C/G cg13789015 chr9:136890014 NCRNA00094 -0.44 -8.14 -0.4 7.23e-15 Platelet distribution width; LIHC cis rs709400 0.832 rs55864158 chr14:104068579 G/A cg26031613 chr14:104095156 KLC1 1.14 14.82 0.63 1.04e-38 Body mass index; LIHC cis rs2806561 0.734 rs2143156 chr1:23374629 T/G cg12483005 chr1:23474871 LUZP1 0.45 6.85 0.35 3.51e-11 Height; LIHC trans rs6934970 1.000 rs12196496 chr6:113021779 T/A cg09308777 chr6:169852575 NA 0.58 6.2 0.32 1.6e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6060717 0.610 rs6060755 chr20:34606915 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.44 -7.13 -0.36 5.92e-12 Hip circumference adjusted for BMI; LIHC cis rs2637266 0.967 rs4608018 chr10:78376110 T/C cg18941641 chr10:78392320 NA 0.29 6.36 0.32 6.66e-10 Pulmonary function; LIHC cis rs9814567 1.000 rs7371896 chr3:134249769 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7618501 0.602 rs2013208 chr3:50129399 C/T cg21467203 chr3:49911342 NA 0.44 7.74 0.39 1.1e-13 Intelligence (multi-trait analysis); LIHC cis rs4908768 0.501 rs4908761 chr1:8552219 G/A cg20416874 chr1:8611966 RERE -0.65 -13.51 -0.59 1.31e-33 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg03060546 chr3:49711283 APEH 0.39 5.87 0.3 1.01e-8 Menarche (age at onset); LIHC cis rs8017423 0.845 rs80167706 chr14:90727629 G/C cg14092571 chr14:90743983 NA -0.38 -6.02 -0.31 4.54e-9 Mortality in heart failure; LIHC cis rs2412488 0.927 rs1481819 chr4:54254146 G/A cg22241045 chr4:54363911 LNX1 -0.46 -7.29 -0.37 2.2e-12 DNA methylation (variation); LIHC trans rs931812 0.964 rs2102290 chr8:101919844 G/C cg20993868 chr7:22813445 NA 0.29 6.36 0.33 6.44e-10 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg18357526 chr6:26021779 HIST1H4A 0.94 11.06 0.51 1.58e-24 Intelligence (multi-trait analysis); LIHC cis rs10744422 1.000 rs921808 chr12:123323135 A/G cg07706471 chr12:123319906 HIP1R 0.57 7.62 0.38 2.57e-13 Schizophrenia; LIHC cis rs1707322 1.000 rs11211232 chr1:46411146 C/T cg03146154 chr1:46216737 IPP 0.47 7.63 0.38 2.31e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs2842992 0.714 rs2495278 chr6:160123674 G/A cg26839252 chr6:160211577 TCP1;MRPL18 0.35 5.96 0.31 6.29e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs9911578 0.900 rs8067264 chr17:57182793 G/C cg12560992 chr17:57184187 TRIM37 0.97 17.94 0.7 3.35e-51 Intelligence (multi-trait analysis); LIHC cis rs546131 0.642 rs1594425 chr11:34833322 C/T cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.67 -0.34 1.04e-10 Lung disease severity in cystic fibrosis; LIHC cis rs317689 0.690 rs7969559 chr12:69655167 A/G cg14784868 chr12:69753453 YEATS4 0.53 7.53 0.38 4.48e-13 Response to diuretic therapy; LIHC cis rs2439831 0.850 rs28413881 chr15:44174099 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 5.81 0.3 1.47e-8 Lung cancer in ever smokers; LIHC cis rs3806843 0.900 rs2337984 chr5:140136811 G/A cg19875535 chr5:140030758 IK -0.37 -6.01 -0.31 4.68e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs17685 0.884 rs8565 chr7:75630274 T/C cg16684958 chr7:75615977 POR -0.51 -8.54 -0.42 4.47e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7582720 0.943 rs72934734 chr2:203739970 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs56104184 0.775 rs56149557 chr19:49401384 C/A cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg23152667 chr5:77072348 TBCA -0.46 -6.5 -0.33 2.76e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2016586 0.802 rs5999972 chr22:36115542 A/C cg26342177 chr22:36113512 APOL5 -0.39 -6.55 -0.33 2.13e-10 Body mass index; LIHC cis rs2760061 0.655 rs686533 chr1:228119604 A/G cg02753203 chr1:228287806 NA -0.5 -8.04 -0.4 1.53e-14 Diastolic blood pressure; LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.7 0.38 1.5e-13 Prudent dietary pattern; LIHC cis rs769267 0.930 rs10414830 chr19:19562332 C/T cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.87 0.3 1.01e-8 Tonsillectomy; LIHC cis rs10847980 0.590 rs78462864 chr12:123365867 C/T cg22842854 chr12:123319900 HIP1R 0.88 8.94 0.44 2.48e-17 Adiponectin levels; LIHC cis rs6831352 0.693 rs2602875 chr4:100039495 C/G cg12011299 chr4:100065546 ADH4 0.56 9.84 0.47 2.69e-20 Alcohol dependence; LIHC cis rs11711311 1.000 rs921741 chr3:113444051 A/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.42 7.88 0.39 4.34e-14 IgG glycosylation; LIHC cis rs6089584 0.889 rs6142923 chr20:60596617 C/T cg13770153 chr20:60521292 NA 0.37 7.17 0.36 4.73e-12 Body mass index; LIHC cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg06238570 chr21:40685208 BRWD1 0.48 7.75 0.39 1.08e-13 Cognitive function; LIHC cis rs12478296 1.000 rs56387669 chr2:243043889 T/C cg18898632 chr2:242989856 NA -0.58 -7.77 -0.39 9.21e-14 Obesity-related traits; LIHC cis rs2228479 0.850 rs11641552 chr16:89838700 C/A cg05185784 chr16:90016020 DEF8 -0.48 -5.92 -0.3 7.94e-9 Skin colour saturation; LIHC cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs57244997 0.725 rs7742640 chr6:162413624 T/C cg17173639 chr6:162384350 PARK2 -0.52 -6.8 -0.35 4.65e-11 Mosquito bite size; LIHC trans rs61931739 0.500 rs11053193 chr12:34438838 G/T cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs929354 0.772 rs4716460 chr7:156970054 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs1707322 1.000 rs10890353 chr1:46298383 G/T cg03146154 chr1:46216737 IPP 0.47 7.76 0.39 9.96e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11234065 chr5:89825590 LYSMD3 0.41 6.33 0.32 7.48e-10 Pancreatic cancer; LIHC cis rs1198430 0.852 rs909537 chr1:23810063 C/G cg19827787 chr1:23763612 ASAP3 0.38 6.68 0.34 9.55e-11 Total cholesterol levels; LIHC cis rs72772090 0.710 rs112178674 chr5:96060355 C/T cg17330273 chr5:96107758 CAST;ERAP1 -0.65 -7.2 -0.36 3.82e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2153535 0.580 rs9393025 chr6:8490618 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs7568458 0.709 rs1446669 chr2:85762209 T/C cg02493740 chr2:85810744 VAMP5 -0.44 -7.53 -0.38 4.55e-13 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg25894440 chr7:65020034 NA -0.54 -6.22 -0.32 1.43e-9 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14797243 chr11:68671428 IGHMBP2;MRPL21 0.48 7.17 0.36 4.54e-12 Pancreatic cancer; LIHC cis rs17106184 1.000 rs60483827 chr1:51301657 G/A cg07174182 chr1:51127561 FAF1 -0.63 -6.72 -0.34 7.77e-11 Type 2 diabetes; LIHC cis rs6586163 1.000 rs1324551 chr10:90751516 C/T cg03111039 chr10:90751583 FAS;ACTA2 -0.59 -8.76 -0.43 9.2e-17 Chronic lymphocytic leukemia; LIHC cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg26874164 chr19:58962979 ZNF324B 0.59 9.16 0.44 4.85e-18 Uric acid clearance; LIHC cis rs1075232 1.000 rs4450360 chr15:31682030 G/A cg01030201 chr15:31746330 NA -0.81 -6.25 -0.32 1.21e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs56011263 0.687 rs4690293 chr4:706101 A/G cg20735989 chr4:730612 PCGF3 -0.66 -8.92 -0.43 2.86e-17 White blood cell count; LIHC cis rs35883536 0.647 rs10875315 chr1:101044062 G/A cg14515779 chr1:101123966 NA 0.48 6.95 0.35 1.83e-11 Monocyte count; LIHC cis rs13064411 0.696 rs6768648 chr3:113234141 C/G cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.09e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs9596863 0.898 rs35646102 chr13:54364897 G/T ch.13.53330881F chr13:54432880 NA 0.43 5.8 0.3 1.53e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs10751667 0.580 rs10751664 chr11:927077 T/G cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC cis rs112790992 1 rs112790992 chr14:105758217 A/C cg13114125 chr14:105738426 BRF1 -0.67 -9.14 -0.44 5.87e-18 Platelet count; LIHC cis rs1448094 0.512 rs7970081 chr12:86243392 G/T cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC trans rs11098499 0.954 rs11722872 chr4:120233030 G/C cg25214090 chr10:38739885 LOC399744 0.57 9.05 0.44 1.13e-17 Corneal astigmatism; LIHC cis rs12477438 0.520 rs11685759 chr2:99766217 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC cis rs9303401 0.659 rs17222691 chr17:56771096 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.27 0.58 1.07e-32 Cognitive test performance; LIHC cis rs635808 0.520 rs656938 chr6:167172048 C/T cg05573767 chr6:167171394 RPS6KA2 0.34 7.49 0.38 5.99e-13 Dental caries; LIHC cis rs12220238 0.915 rs11000987 chr10:76073265 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs3741404 0.825 rs2845597 chr11:63954370 G/A cg04317338 chr11:64019027 PLCB3 0.49 6.81 0.35 4.48e-11 Platelet count; LIHC cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -11.92 -0.54 1.19e-27 Alzheimer's disease; LIHC trans rs5756813 0.700 rs1894525 chr22:38186400 G/A cg19894588 chr14:64061835 NA -0.63 -8.81 -0.43 6.48e-17 Optic cup area;Vertical cup-disc ratio; LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg27432699 chr2:27873401 GPN1 -0.49 -6.9 -0.35 2.47e-11 Menopause (age at onset); LIHC cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg17554472 chr22:41940697 POLR3H 0.54 5.8 0.3 1.48e-8 Vitiligo; LIHC cis rs1046896 0.520 rs8074086 chr17:80818460 A/C cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.34 0.32 7.2e-10 Glycated hemoglobin levels; LIHC cis rs5758511 0.514 rs5751222 chr22:42517922 T/A cg20195005 chr22:42527684 CYP2D6 0.32 6.15 0.32 2.19e-9 Birth weight; LIHC cis rs7208859 0.673 rs7211776 chr17:29120196 T/G cg13385521 chr17:29058706 SUZ12P 0.8 8.19 0.4 5.35e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg21003380 chr1:156261207 TMEM79 0.38 6.07 0.31 3.49e-9 Tonsillectomy; LIHC cis rs1018836 0.669 rs6471243 chr8:91656967 C/T cg16814680 chr8:91681699 NA 0.98 16.95 0.68 3.29e-47 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs208520 0.690 rs12198745 chr6:66722598 T/C cg07460842 chr6:66804631 NA 0.75 8.71 0.43 1.33e-16 Exhaled nitric oxide output; LIHC trans rs6866721 0.791 rs7704477 chr5:116217035 A/G cg07571379 chr11:134631427 NA -0.28 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs6674176 0.561 rs4660263 chr1:44421433 A/C cg12908607 chr1:44402522 ARTN -0.51 -8.56 -0.42 3.76e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs778371 0.958 rs2675968 chr2:233736244 A/G cg08000102 chr2:233561755 GIGYF2 0.84 13.46 0.59 1.96e-33 Schizophrenia; LIHC cis rs6499255 0.951 rs11642030 chr16:69605211 A/C cg15192750 chr16:69999425 NA 0.47 7.03 0.36 1.11e-11 IgE levels; LIHC cis rs769267 0.930 rs10419912 chr19:19597055 A/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.53 -7.99 -0.4 2.1e-14 Tonsillectomy; LIHC cis rs1552244 0.572 rs6785976 chr3:10168647 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.84 -9.99 -0.48 8.96e-21 Alzheimer's disease; LIHC cis rs7312933 0.558 rs7965743 chr12:42736822 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.25 -0.41 3.44e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs796364 1.000 rs281759 chr2:200787719 T/C cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.67e-9 Schizophrenia; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg14709524 chr16:89940631 TCF25 0.54 7.0 0.35 1.33e-11 Skin colour saturation; LIHC cis rs8027181 0.682 rs11637168 chr15:73100694 C/A cg25996835 chr15:72978165 BBS4;HIGD2B 0.43 6.73 0.34 7.07e-11 Triglyceride levels; LIHC cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg02034447 chr16:89574710 SPG7 0.5 7.67 0.38 1.82e-13 Multiple myeloma (IgH translocation); LIHC trans rs4942242 0.663 rs1390371 chr13:44211727 A/G cg19169023 chr15:41853346 TYRO3 0.5 7.18 0.36 4.25e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs7772486 0.754 rs6906258 chr6:146089356 A/G cg23711669 chr6:146136114 FBXO30 -0.74 -13.25 -0.58 1.28e-32 Lobe attachment (rater-scored or self-reported); LIHC trans rs10411161 0.702 rs10423835 chr19:52387322 A/G cg22319618 chr22:45562946 NUP50 -0.61 -8.42 -0.41 1.06e-15 Breast cancer; LIHC cis rs2580764 0.573 rs13387751 chr2:55227375 C/G cg09592903 chr2:55203963 RTN4 -0.69 -12.54 -0.56 5.98e-30 Mean platelet volume; LIHC cis rs67478160 0.619 rs3742365 chr14:104198251 A/G cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs6570726 0.935 rs384519 chr6:145846017 C/A cg23711669 chr6:146136114 FBXO30 0.57 10.11 0.48 3.39e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769765 0.862 rs9616392 chr22:50314705 G/A cg26441486 chr22:50317300 CRELD2 0.36 5.77 0.3 1.77e-8 Schizophrenia; LIHC cis rs561341 0.739 rs8070554 chr17:30216868 A/T cg13647721 chr17:30228624 UTP6 -0.71 -8.06 -0.4 1.3e-14 Hip circumference adjusted for BMI; LIHC cis rs7223966 1.000 rs56383601 chr17:61929968 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.74 0.34 6.75e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs739401 0.611 rs2239899 chr11:3024624 A/G cg20651018 chr11:3035856 CARS 0.36 6.13 0.31 2.36e-9 Longevity; LIHC cis rs1552244 0.554 rs3774207 chr3:9985656 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.53 -8.59 -0.42 3.22e-16 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24656492 chr10:70940659 SUPV3L1 0.46 6.73 0.34 7.09e-11 Cognitive function; LIHC cis rs826838 0.874 rs11183816 chr12:38834656 T/G cg26384229 chr12:38710491 ALG10B 1.06 14.27 0.61 1.46e-36 Heart rate; LIHC cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.89 0.3 9.32e-9 Menopause (age at onset); LIHC cis rs6964587 1.000 rs9785013 chr7:91674302 G/A cg17063962 chr7:91808500 NA 1.03 20.93 0.75 3.47e-63 Breast cancer; LIHC cis rs7772486 0.727 rs10447449 chr6:146138707 A/G cg23711669 chr6:146136114 FBXO30 0.64 11.58 0.53 2.1e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.659 rs62083436 chr17:57031742 G/A cg25039879 chr17:56429692 SUPT4H1 0.79 8.95 0.44 2.37e-17 Cognitive test performance; LIHC cis rs7707921 0.767 rs6894520 chr5:81594748 C/T cg15871215 chr5:81402204 ATG10 -0.67 -8.01 -0.4 1.87e-14 Breast cancer; LIHC cis rs72781680 1.000 rs72796316 chr2:24132272 T/C cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs28374715 0.532 rs7168431 chr15:41672384 A/G cg18705301 chr15:41695430 NDUFAF1 -1.26 -18.85 -0.71 7.11e-55 Ulcerative colitis; LIHC cis rs16866061 0.962 rs16825685 chr2:225434256 C/G cg12698349 chr2:225449008 CUL3 0.8 14.16 0.61 3.74e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs11098499 0.863 rs13140391 chr4:120503437 A/G cg25214090 chr10:38739885 LOC399744 0.58 9.51 0.46 3.44e-19 Corneal astigmatism; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg04234412 chr22:24373322 LOC391322 -0.71 -10.95 -0.51 4.09e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs637571 0.528 rs11602769 chr11:65594139 T/C cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.69 -0.34 9.35e-11 Eosinophil percentage of white cells; LIHC cis rs2153535 0.580 rs1932275 chr6:8442333 T/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs763121 0.815 rs4821799 chr22:39021326 T/G cg21395723 chr22:39101663 GTPBP1 0.36 6.22 0.32 1.46e-9 Menopause (age at onset); LIHC cis rs77861329 1.000 rs59890038 chr3:52147850 A/G cg08692210 chr3:52188851 WDR51A 0.85 8.07 0.4 1.24e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs11690935 0.959 rs10204501 chr2:172588865 C/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.77 -0.69 1.66e-50 Schizophrenia; LIHC trans rs7395662 0.591 rs7483212 chr11:48607182 T/A cg03929089 chr4:120376271 NA -0.4 -6.09 -0.31 3.02e-9 HDL cholesterol; LIHC cis rs9916302 0.706 rs9891892 chr17:37479856 A/C cg07936489 chr17:37558343 FBXL20 0.85 12.22 0.55 9.54e-29 Glomerular filtration rate (creatinine); LIHC trans rs10761482 0.500 rs2211220 chr10:62271491 A/G cg14898824 chr12:64851143 TBK1 -0.33 -6.28 -0.32 1.02e-9 Schizophrenia; LIHC cis rs918629 0.530 rs3777193 chr5:95246760 G/A cg10483112 chr5:95245456 ELL2 -0.38 -7.12 -0.36 6.43e-12 IgG glycosylation; LIHC cis rs7520050 0.966 rs809775 chr1:46538040 A/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.73 0.3 2.18e-8 Red blood cell count;Reticulocyte count; LIHC cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg02034447 chr16:89574710 SPG7 0.49 7.33 0.37 1.73e-12 Multiple myeloma (IgH translocation); LIHC cis rs1707322 1.000 rs6693336 chr1:46354595 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.78e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9549367 0.662 rs3818334 chr13:113825174 C/G cg00898013 chr13:113819073 PROZ -0.44 -7.23 -0.36 3.14e-12 Platelet distribution width; LIHC cis rs6598955 0.502 rs6683157 chr1:26545865 G/A cg04990556 chr1:26633338 UBXN11 0.76 11.03 0.51 2.02e-24 Obesity-related traits; LIHC cis rs9300255 0.568 rs1790090 chr12:123633424 G/A cg00376283 chr12:123451042 ABCB9 0.59 6.71 0.34 8.15e-11 Neutrophil percentage of white cells; LIHC cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg06634786 chr22:41940651 POLR3H 0.74 7.63 0.38 2.35e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9467773 1.000 rs10946834 chr6:26533664 G/C cg09904177 chr6:26538194 HMGN4 0.66 13.75 0.6 1.53e-34 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13265914 chr8:21999630 REEP4 0.48 7.19 0.36 4.22e-12 Pancreatic cancer; LIHC cis rs1355223 1.000 rs11602909 chr11:34768003 T/C cg11058730 chr11:34937778 PDHX;APIP -0.49 -6.55 -0.33 2.1e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01297674 chr2:122406765 CLASP1 0.43 6.55 0.33 2.15e-10 Cognitive function; LIHC cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg06634786 chr22:41940651 POLR3H 0.8 8.9 0.43 3.22e-17 Vitiligo; LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg13409248 chr3:40428643 ENTPD3 0.49 8.22 0.41 4.34e-15 Renal cell carcinoma; LIHC cis rs9649213 0.574 rs6979373 chr7:97961844 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs55883249 0.957 rs62119431 chr2:9750461 G/A cg23886495 chr2:9695866 ADAM17 0.75 6.8 0.35 4.7e-11 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; LIHC cis rs9814567 0.762 rs13067564 chr3:134209956 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 7.25 0.36 2.87e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4780401 0.573 rs8045673 chr16:11804385 C/A cg01061890 chr16:11836724 TXNDC11 -0.63 -9.95 -0.47 1.16e-20 Rheumatoid arthritis; LIHC cis rs8017423 0.935 rs2104704 chr14:90696609 A/G cg14092571 chr14:90743983 NA 0.4 6.25 0.32 1.19e-9 Mortality in heart failure; LIHC cis rs17152411 0.652 rs4246208 chr10:126654898 C/T cg07906193 chr10:126599966 NA -0.31 -6.16 -0.32 2.02e-9 Height; LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg20102877 chr2:27665638 KRTCAP3 -0.44 -6.07 -0.31 3.38e-9 Total body bone mineral density; LIHC cis rs4727027 0.866 rs35599790 chr7:148806012 C/T cg23583168 chr7:148888333 NA -0.7 -9.73 -0.47 6.44e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6461049 0.800 rs2398706 chr7:2156338 A/T cg21782813 chr7:2030301 MAD1L1 0.36 6.11 0.31 2.76e-9 Schizophrenia; LIHC cis rs526821 0.595 rs499446 chr11:55355722 A/G cg04317927 chr11:55418816 OR4S2 0.47 8.82 0.43 6.11e-17 Pediatric bone mineral density (spine); LIHC cis rs9790314 1.000 rs336593 chr3:161076431 T/C cg03342759 chr3:160939853 NMD3 -0.67 -8.05 -0.4 1.35e-14 Morning vs. evening chronotype; LIHC cis rs6076065 0.894 rs2243448 chr20:23378345 G/A cg11657817 chr20:23433608 CST11 0.33 6.96 0.35 1.74e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs763121 0.853 rs138706 chr22:39137834 C/G cg06022373 chr22:39101656 GTPBP1 0.71 13.76 0.6 1.4e-34 Menopause (age at onset); LIHC cis rs2404602 0.647 rs62026889 chr15:76917885 C/T cg23625390 chr15:77176239 SCAPER -0.53 -8.74 -0.43 1.1e-16 Blood metabolite levels; LIHC cis rs2997447 0.846 rs61775431 chr1:26411275 T/G cg19633962 chr1:26362018 EXTL1 -0.7 -6.4 -0.33 5.06e-10 QRS complex (12-leadsum); LIHC cis rs34779708 0.931 rs4934723 chr10:35381763 A/G cg03585969 chr10:35415529 CREM 0.88 13.19 0.58 2.08e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9900497 0.536 rs4646785 chr17:19651902 A/G cg22552966 chr17:19620595 SLC47A2 -0.47 -9.58 -0.46 2.09e-19 Response to paliperidone in schizophrenia (CGI-S score); LIHC cis rs7647973 0.731 rs13084037 chr3:49214066 G/A cg07636037 chr3:49044803 WDR6 0.49 5.75 0.3 2.01e-8 Menarche (age at onset); LIHC cis rs7086627 0.515 rs4934189 chr10:82214792 C/T cg00277334 chr10:82204260 NA -0.86 -14.23 -0.61 2.11e-36 Post bronchodilator FEV1; LIHC cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg18402987 chr7:1209562 NA 0.76 6.04 0.31 4.04e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2797160 1.000 rs2211420 chr6:125995549 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.44 -6.48 -0.33 3.25e-10 Endometrial cancer; LIHC cis rs240764 0.717 rs239215 chr6:101147426 A/G cg12253828 chr6:101329408 ASCC3 0.42 6.45 0.33 3.74e-10 Neuroticism; LIHC cis rs12594515 1.000 rs12594515 chr15:45985071 C/G cg06207120 chr15:45996521 NA -0.33 -6.23 -0.32 1.41e-9 Waist circumference;Weight; LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg10755058 chr3:40428713 ENTPD3 -0.42 -7.25 -0.36 2.8e-12 Renal cell carcinoma; LIHC cis rs2549003 1.000 rs2549009 chr5:131826765 T/C cg21138405 chr5:131827807 IRF1 -0.38 -9.64 -0.46 1.26e-19 Asthma (sex interaction); LIHC cis rs12477438 0.520 rs13022329 chr2:99731189 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.54 0.77 1.37e-69 Chronic sinus infection; LIHC cis rs5769765 1.000 rs5769765 chr22:50271176 G/A cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg22528358 chr1:107598549 PRMT6 0.72 11.91 0.54 1.35e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2243480 0.901 rs73142137 chr7:65343442 A/T cg12463550 chr7:65579703 CRCP 0.7 7.15 0.36 5.32e-12 Diabetic kidney disease; LIHC cis rs2153535 0.504 rs4493781 chr6:8473941 G/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.15e-16 Motion sickness; LIHC cis rs12980942 0.935 rs1865052 chr19:41824467 G/A cg25627403 chr19:41769009 HNRNPUL1 0.48 5.93 0.31 7.26e-9 Coronary artery disease; LIHC cis rs13394619 0.875 rs9287734 chr2:11724475 A/G cg07314298 chr2:11723111 GREB1 -0.49 -9.28 -0.45 1.99e-18 Endometriosis; LIHC cis rs2439831 0.867 rs12323999 chr15:43683115 T/A cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.86 0.51 8.31e-24 Lung cancer in ever smokers; LIHC cis rs1144333 1.000 rs2202019 chr1:76299181 G/A cg10523679 chr1:76189770 ACADM 0.47 6.79 0.34 5e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs6466055 1.000 rs6466055 chr7:104929064 A/C cg04380332 chr7:105027541 SRPK2 0.34 6.4 0.33 5.02e-10 Schizophrenia; LIHC cis rs6547741 0.844 rs7382 chr2:27873415 G/A cg27432699 chr2:27873401 GPN1 -0.93 -16.39 -0.66 5.96e-45 Oral cavity cancer; LIHC cis rs4908768 0.579 rs12142911 chr1:8857245 C/G cg20416874 chr1:8611966 RERE 0.4 5.77 0.3 1.75e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs12220238 1.000 rs11000931 chr10:75984800 A/C cg19889307 chr10:75911429 ADK;AP3M1 -0.67 -6.74 -0.34 6.71e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7208859 0.623 rs7214570 chr17:29147164 A/G cg13385521 chr17:29058706 SUZ12P 0.78 7.86 0.39 5.18e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs61931739 0.534 rs2220547 chr12:34106255 G/A cg26384229 chr12:38710491 ALG10B 0.53 7.36 0.37 1.38e-12 Morning vs. evening chronotype; LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg11965913 chr1:205819406 PM20D1 0.76 11.18 0.52 6.04e-25 Menarche (age at onset); LIHC cis rs6665290 0.839 rs6699400 chr1:227190497 A/G cg10327440 chr1:227177885 CDC42BPA -1.19 -29.44 -0.85 8.75e-96 Myeloid white cell count; LIHC cis rs8017423 0.647 rs12883000 chr14:90820557 G/A cg04374321 chr14:90722782 PSMC1 -0.5 -7.39 -0.37 1.12e-12 Mortality in heart failure; LIHC cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg12311346 chr5:56204834 C5orf35 -0.58 -7.6 -0.38 2.92e-13 Initial pursuit acceleration; LIHC cis rs2153535 0.560 rs2210798 chr6:8481522 C/T cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC trans rs2262909 0.962 rs425781 chr19:22229306 A/G cg05197062 chr11:11642011 GALNTL4 -0.42 -6.11 -0.31 2.73e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg11060661 chr22:24314208 DDT;DDTL 0.66 11.57 0.53 2.32e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4660306 0.961 rs12145526 chr1:45969036 G/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.66 -8.04 -0.4 1.5e-14 Homocysteine levels; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13173722 chr20:60553138 TAF4 0.48 6.49 0.33 3.03e-10 Hepatitis; LIHC cis rs829883 0.738 rs249846 chr12:98868739 T/C cg25150519 chr12:98850993 NA 0.67 10.26 0.49 1.02e-21 Colorectal adenoma (advanced); LIHC trans rs10761482 0.500 rs7098650 chr10:62277679 C/T cg17314160 chr12:110399253 GIT2 -0.43 -6.28 -0.32 1.01e-9 Schizophrenia; LIHC cis rs9649465 0.967 rs9641717 chr7:123350060 C/T cg03229431 chr7:123269106 ASB15 -0.37 -7.8 -0.39 7.33e-14 Migraine; LIHC cis rs7106204 0.686 rs12790317 chr11:24254405 T/C ch.11.24196551F chr11:24239977 NA 0.59 6.35 0.32 6.8e-10 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6088580 0.524 rs11167241 chr20:33250835 C/T cg07148914 chr20:33460835 GGT7 -0.51 -7.19 -0.36 4.11e-12 Glomerular filtration rate (creatinine); LIHC cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.23 -0.55 8.74e-29 Alzheimer's disease; LIHC cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg16822855 chr3:40428330 ENTPD3 -0.32 -5.74 -0.3 2.11e-8 Renal cell carcinoma; LIHC cis rs738322 0.967 rs132985 chr22:38563471 C/T cg25457927 chr22:38595422 NA -0.25 -5.97 -0.31 5.96e-9 Cutaneous nevi; LIHC cis rs2836974 0.666 rs12626405 chr21:40663121 G/T cg06238570 chr21:40685208 BRWD1 -0.55 -9.06 -0.44 1.05e-17 Cognitive function; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg06577708 chr3:64008893 PSMD6 0.42 6.1 0.31 2.79e-9 Migraine with aura; LIHC cis rs7131987 0.650 rs10843382 chr12:29451721 G/A cg14222432 chr12:29376421 FAR2 0.36 6.97 0.35 1.68e-11 QT interval; LIHC cis rs8141529 0.702 rs8137262 chr22:29292135 C/T cg15103426 chr22:29168792 CCDC117 0.57 9.26 0.45 2.32e-18 Lymphocyte counts; LIHC cis rs17106184 1.000 rs58795848 chr1:51283510 A/G cg07174182 chr1:51127561 FAF1 -0.64 -7.22 -0.36 3.47e-12 Type 2 diabetes; LIHC cis rs34779708 0.966 rs1213392 chr10:35430285 C/T cg03585969 chr10:35415529 CREM 0.77 11.65 0.53 1.23e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7953249 0.656 rs2251468 chr12:121405126 A/C cg02403541 chr12:121454288 C12orf43 0.42 7.26 0.37 2.7e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs13191362 1.000 rs67025553 chr6:163011552 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.77 0.3 1.82e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6500602 0.855 rs2304631 chr16:4475868 A/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.06 0.31 3.67e-9 Schizophrenia; LIHC cis rs12403795 0.505 rs11811787 chr1:150200487 C/T cg15654264 chr1:150340011 RPRD2 -0.4 -5.84 -0.3 1.21e-8 Illicit drug use; LIHC cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg10360323 chr17:41437877 NA 0.39 5.75 0.3 1.98e-8 Menopause (age at onset); LIHC cis rs4423214 0.592 rs79634040 chr11:71230169 G/C cg05163923 chr11:71159392 DHCR7 -0.59 -7.24 -0.36 2.96e-12 Vitamin D levels; LIHC cis rs62064224 0.560 rs12162135 chr17:30805795 A/C cg18200150 chr17:30822561 MYO1D 0.32 6.82 0.35 4.13e-11 Schizophrenia; LIHC cis rs864643 1.000 rs1513213 chr3:39550897 G/A cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.31 -0.32 8.81e-10 Total body bone mineral density; LIHC cis rs10751667 0.666 rs6597967 chr11:950583 G/T cg10932868 chr11:921992 NA 0.37 7.0 0.35 1.33e-11 Alzheimer's disease (late onset); LIHC cis rs6952808 0.792 rs12531315 chr7:1953650 C/G cg14004847 chr7:1930337 MAD1L1 -0.48 -6.84 -0.35 3.62e-11 Bipolar disorder and schizophrenia; LIHC trans rs11098499 0.820 rs13122709 chr4:120555356 T/A cg25214090 chr10:38739885 LOC399744 0.56 8.85 0.43 4.65e-17 Corneal astigmatism; LIHC cis rs2404602 0.647 rs12903331 chr15:77168268 C/G cg23625390 chr15:77176239 SCAPER -0.56 -9.53 -0.46 3.04e-19 Blood metabolite levels; LIHC trans rs877282 0.898 rs11253338 chr10:759559 C/T cg22713356 chr15:30763199 NA 1.21 10.85 0.51 9.25e-24 Uric acid levels; LIHC cis rs9309711 0.666 rs6767 chr2:3483205 C/T cg04359351 chr2:3481828 TTC15 0.28 5.94 0.31 7.04e-9 Neurofibrillary tangles; LIHC cis rs8177253 0.507 rs4241357 chr3:133475563 A/C cg12373951 chr3:133503437 NA -0.43 -6.67 -0.34 1.01e-10 Iron status biomarkers; LIHC trans rs3743102 0.527 rs117959961 chr15:83339895 C/T cg01542190 chr22:50604728 NA -0.54 -7.18 -0.36 4.29e-12 Colorectal adenoma (advanced); LIHC cis rs6500602 0.702 rs2304634 chr16:4500544 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.48 7.6 0.38 2.88e-13 Schizophrenia; LIHC cis rs8083850 0.635 rs9954344 chr18:50861056 C/G cg24270629 chr18:50823537 DCC 0.56 8.41 0.41 1.16e-15 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg00091569 chr3:40428383 ENTPD3 0.38 6.27 0.32 1.09e-9 Renal cell carcinoma; LIHC cis rs9790314 1.000 rs336593 chr3:161076431 T/C cg04691961 chr3:161091175 C3orf57 -0.46 -7.34 -0.37 1.54e-12 Morning vs. evening chronotype; LIHC cis rs7552404 1.000 rs11161515 chr1:76212559 C/T cg22875332 chr1:76189707 ACADM 0.46 6.74 0.34 6.88e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs700651 0.752 rs1850631 chr2:198829468 T/G cg00792783 chr2:198669748 PLCL1 0.45 6.69 0.34 9.26e-11 Intracranial aneurysm; LIHC trans rs3858145 0.588 rs4142049 chr10:70044452 C/A cg04882175 chr6:131122610 NA -0.51 -6.09 -0.31 3.06e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs7412746 0.611 rs4319334 chr1:150766822 G/A cg17724175 chr1:150552817 MCL1 0.43 8.59 0.42 3.2e-16 Melanoma; LIHC cis rs2153535 0.580 rs2327056 chr6:8443305 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs34779708 0.966 rs12782948 chr10:35450607 G/A cg03585969 chr10:35415529 CREM 0.86 12.83 0.57 5.16e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9325144 0.647 rs1875609 chr12:39018259 C/T cg26384229 chr12:38710491 ALG10B -0.43 -6.12 -0.31 2.56e-9 Morning vs. evening chronotype; LIHC cis rs6061231 0.561 rs67072353 chr20:60940702 G/A cg09594475 chr20:60884601 LAMA5 0.58 6.56 0.33 1.94e-10 Colorectal cancer; LIHC cis rs651907 0.514 rs12636047 chr3:101434449 T/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.5 -0.33 2.85e-10 Colorectal cancer; LIHC cis rs644799 1.000 rs611020 chr11:95567905 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.51 0.46 3.51e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg05754148 chr16:3507555 NAT15 0.39 5.9 0.3 8.89e-9 Tuberculosis; LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg11494091 chr17:61959527 GH2 0.43 7.87 0.39 4.56e-14 Prudent dietary pattern; LIHC cis rs2153535 0.623 rs2327055 chr6:8443145 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.37 0.41 1.53e-15 Motion sickness; LIHC cis rs7647973 1.000 rs13322887 chr3:49555583 G/A cg07636037 chr3:49044803 WDR6 -0.54 -6.65 -0.34 1.18e-10 Menarche (age at onset); LIHC cis rs1008375 0.932 rs4698630 chr4:17614692 C/G cg02297831 chr4:17616191 MED28 0.49 7.61 0.38 2.63e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs62012628 0.527 rs12438008 chr15:79084680 C/T cg22753661 chr15:79092743 ADAMTS7 -0.37 -5.78 -0.3 1.7e-8 Diastolic blood pressure; LIHC cis rs7582720 1.000 rs72934537 chr2:203969504 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs903552 1.000 rs4965873 chr15:102004023 A/G cg19295451 chr15:102010161 PCSK6 0.47 6.52 0.33 2.52e-10 Diabetic kidney disease; LIHC cis rs2204008 0.576 rs11519979 chr12:37999413 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg09863094 chr10:134546253 INPP5A 0.4 6.12 0.31 2.55e-9 Immature fraction of reticulocytes; LIHC cis rs11166927 0.901 rs7014257 chr8:140802694 G/T cg16909799 chr8:140841666 TRAPPC9 0.5 7.9 0.39 3.92e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03226425 chr6:170151538 C6orf70;TCTE3 0.53 7.89 0.39 4.25e-14 Cognitive function; LIHC cis rs10911232 0.507 rs10797815 chr1:182996827 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs10876993 0.855 rs10877007 chr12:58100058 T/A cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -5.9 -0.3 8.63e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs7715806 0.500 rs888788 chr5:74988336 C/T cg19683494 chr5:74908142 NA 0.69 7.93 0.39 3.15e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg09060608 chr5:178986726 RUFY1 0.41 6.32 0.32 8.33e-10 Lung cancer; LIHC cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg12756686 chr19:29218302 NA 0.43 6.43 0.33 4.37e-10 Methadone dose in opioid dependence; LIHC cis rs17106184 1.000 rs72904737 chr1:51351846 G/A cg07174182 chr1:51127561 FAF1 -0.59 -6.12 -0.31 2.52e-9 Type 2 diabetes; LIHC cis rs4934494 0.727 rs36019294 chr10:91537579 G/A cg19698084 chr10:91461284 KIF20B -0.44 -5.88 -0.3 9.5e-9 Red blood cell count; LIHC cis rs12762955 0.528 rs10903358 chr10:1102386 G/A cg20503657 chr10:835505 NA 0.7 6.51 0.33 2.72e-10 Response to angiotensin II receptor blocker therapy; LIHC cis rs9291683 0.609 rs12507050 chr4:10007305 G/T cg11266682 chr4:10021025 SLC2A9 0.31 6.39 0.33 5.42e-10 Bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03900353 chr1:212732456 NA 0.39 6.33 0.32 7.87e-10 Cognitive function; LIHC cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.95 0.31 6.81e-9 Schizophrenia; LIHC cis rs12220238 1.000 rs10824103 chr10:75949415 A/T cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.38 0.33 5.76e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2274273 0.935 rs8004787 chr14:55607366 C/T cg01864836 chr14:55583639 NA -0.42 -8.19 -0.4 5.27e-15 Protein biomarker; LIHC cis rs6952808 0.543 rs4719436 chr7:2141239 G/A cg02951883 chr7:2050386 MAD1L1 -0.64 -10.51 -0.49 1.38e-22 Bipolar disorder and schizophrenia; LIHC cis rs7582720 1.000 rs72932784 chr2:203698470 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6973256 0.568 rs7800126 chr7:133521356 A/C cg10665199 chr7:133106180 EXOC4 0.35 5.85 0.3 1.14e-8 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.904 rs9904334 chr17:37468336 G/A cg03013999 chr17:37608204 MED1 -0.36 -6.07 -0.31 3.33e-9 Glomerular filtration rate (creatinine); LIHC cis rs1728785 1.000 rs889561 chr16:68605741 G/A cg02972257 chr16:68554789 NA -0.57 -6.51 -0.33 2.7e-10 Ulcerative colitis; LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs7613875 0.580 rs11709503 chr3:49991167 G/T cg24110177 chr3:50126178 RBM5 -0.52 -8.16 -0.4 6.64e-15 Body mass index; LIHC cis rs763121 0.853 rs3827357 chr22:39079413 A/G cg06022373 chr22:39101656 GTPBP1 0.65 11.25 0.52 3.49e-25 Menopause (age at onset); LIHC cis rs765787 0.530 rs1706834 chr15:45517854 G/A cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.81 -0.3 1.42e-8 Uric acid levels; LIHC cis rs9399135 0.967 rs4142299 chr6:135377186 G/T cg24558204 chr6:135376177 HBS1L 0.44 7.22 0.36 3.5e-12 Red blood cell count; LIHC cis rs2361718 0.527 rs7211994 chr17:78152514 A/G cg09238746 chr17:78121135 EIF4A3 0.41 6.3 0.32 9.38e-10 Yeast infection; LIHC cis rs2073300 0.609 rs6137910 chr20:23346515 C/G cg12062639 chr20:23401060 NAPB 1.07 14.34 0.61 7.59e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6831256 1.000 rs10007119 chr4:3473066 A/G cg22890737 chr4:3514540 LRPAP1 0.44 7.21 0.36 3.55e-12 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg03517284 chr6:25882590 NA 0.53 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs7224685 1.000 rs1377807 chr17:4045440 C/G cg09695851 chr17:3907499 NA 0.69 8.62 0.42 2.6e-16 Type 2 diabetes; LIHC cis rs4728302 0.869 rs6955279 chr7:133612113 C/T cg10665199 chr7:133106180 EXOC4 0.4 6.92 0.35 2.3e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg05896524 chr21:47604654 C21orf56 -0.46 -7.1 -0.36 7.48e-12 Testicular germ cell tumor; LIHC cis rs13191362 1.000 rs13207239 chr6:163008772 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1670533 1.000 rs4690212 chr4:1054898 T/C cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg20607798 chr8:58055168 NA 0.59 6.94 0.35 1.92e-11 Developmental language disorder (linguistic errors); LIHC cis rs796364 1.000 rs11895190 chr2:200838613 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.77 -9.22 -0.45 3.14e-18 Schizophrenia; LIHC cis rs10504229 0.953 rs114806125 chr8:58182416 C/T cg02290350 chr8:58132656 NA 0.41 8.7 0.43 1.43e-16 Developmental language disorder (linguistic errors); LIHC cis rs6754311 0.509 rs12616520 chr2:136516748 A/T cg07305463 chr2:136567211 LCT 0.37 6.44 0.33 4.01e-10 Mosquito bite size; LIHC cis rs1434579 0.615 rs1560915 chr19:44937379 C/T cg15540054 chr19:45004280 ZNF180 0.65 9.81 0.47 3.44e-20 Tuberculosis; LIHC cis rs6663390 0.510 rs2267897 chr1:208075378 C/T cg03990033 chr1:208084030 CD34 0.48 5.8 0.3 1.53e-8 Facial morphology (factor 18); LIHC cis rs12220238 1.000 rs10824083 chr10:75911342 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.77 0.34 5.63e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs932287 0.536 rs10840160 chr11:9053536 C/T cg12365402 chr11:9010492 NRIP3 -0.28 -7.21 -0.36 3.58e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg04025307 chr7:1156635 C7orf50 0.67 11.86 0.54 2.12e-27 Longevity;Endometriosis; LIHC cis rs7605378 0.528 rs281791 chr2:200850402 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.55 -7.31 -0.37 1.9e-12 Osteoporosis; LIHC cis rs1144333 0.655 rs1144337 chr1:76278877 A/G cg10523679 chr1:76189770 ACADM -0.45 -6.66 -0.34 1.07e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs7216064 1.000 rs7212293 chr17:65847325 A/G cg12091567 chr17:66097778 LOC651250 -0.65 -9.6 -0.46 1.77e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg02187348 chr16:89574699 SPG7 -0.64 -10.53 -0.49 1.21e-22 Multiple myeloma (IgH translocation); LIHC cis rs4713118 0.869 rs7776351 chr6:27726731 A/G cg20933634 chr6:27740509 NA -0.43 -5.78 -0.3 1.71e-8 Parkinson's disease; LIHC cis rs9905704 0.647 rs3809723 chr17:57061978 T/G cg05425664 chr17:57184151 TRIM37 -0.43 -6.0 -0.31 5.13e-9 Testicular germ cell tumor; LIHC cis rs9733 0.818 rs12130363 chr1:150688596 T/C cg18016565 chr1:150552671 MCL1 -0.5 -10.32 -0.49 6.68e-22 Tonsillectomy; LIHC cis rs738322 0.967 rs133017 chr22:38572637 A/C cg25457927 chr22:38595422 NA -0.27 -6.61 -0.34 1.51e-10 Cutaneous nevi; LIHC cis rs7129220 0.512 rs16907504 chr11:10169531 C/G cg01453529 chr11:10209919 SBF2 -0.37 -6.71 -0.34 7.98e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs1023500 0.573 rs133381 chr22:42470608 C/G cg05082376 chr22:42548792 NA -0.4 -5.93 -0.31 7.52e-9 Schizophrenia; LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.64 -10.39 -0.49 3.66e-22 Prudent dietary pattern; LIHC cis rs1580019 0.961 rs4460271 chr7:32496503 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs2777491 0.574 rs2730056 chr15:41735785 A/G cg18705301 chr15:41695430 NDUFAF1 -1.26 -18.71 -0.71 2.75e-54 Ulcerative colitis; LIHC cis rs8067354 0.574 rs2250526 chr17:57951973 G/A cg13753209 chr17:57696993 CLTC 0.69 10.21 0.48 1.52e-21 Hemoglobin concentration; LIHC cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg13047869 chr3:10149882 C3orf24 0.48 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs7618501 0.521 rs2883059 chr3:49902160 C/T cg24110177 chr3:50126178 RBM5 0.56 8.91 0.43 3.14e-17 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.577 rs2887951 chr3:40282104 C/G cg18306943 chr3:40428807 ENTPD3 0.35 5.87 0.3 1.01e-8 Renal cell carcinoma; LIHC cis rs864643 1.000 rs866537 chr3:39571616 T/C cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs12791968 0.765 rs12790121 chr11:45001089 G/A cg11846598 chr11:44996168 LOC221122 -0.42 -6.73 -0.34 7e-11 Inhibitory control; LIHC cis rs10791097 0.694 rs1893017 chr11:130756253 C/T cg14779329 chr11:130786720 SNX19 0.42 6.34 0.32 7.1e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs3736228 0.604 rs3018716 chr11:68404222 T/C cg16797656 chr11:68205561 LRP5 0.49 6.24 0.32 1.3e-9 Bone mineral density; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11032208 chr5:95997736 CAST -0.54 -6.73 -0.34 7.03e-11 Systolic blood pressure; LIHC cis rs6977660 0.714 rs10249477 chr7:19805388 T/A cg07541023 chr7:19748670 TWISTNB 0.39 5.83 0.3 1.29e-8 Thyroid stimulating hormone; LIHC cis rs6456156 0.586 rs2017338 chr6:167471714 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.69 -0.43 1.56e-16 Primary biliary cholangitis; LIHC cis rs116095464 0.558 rs9654452 chr5:299561 C/T cg22496380 chr5:211416 CCDC127 -1.01 -10.4 -0.49 3.45e-22 Breast cancer; LIHC cis rs5769765 0.778 rs8137331 chr22:50313358 G/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.73 -9.18 -0.44 4.23e-18 Schizophrenia; LIHC cis rs2282526 0.615 rs162377 chr21:44926001 A/G cg21573476 chr21:45109991 RRP1B -0.51 -9.09 -0.44 8.36e-18 Mean corpuscular hemoglobin; LIHC cis rs1163251 0.902 rs483360 chr1:120200606 C/T cg19096424 chr1:120255104 PHGDH -0.61 -7.38 -0.37 1.2e-12 Blood metabolite levels; LIHC cis rs611744 0.901 rs673981 chr8:109191917 G/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs875971 0.660 rs62465434 chr7:66005152 A/C cg18876405 chr7:65276391 NA 0.44 7.78 0.39 8.74e-14 Aortic root size; LIHC trans rs10411161 1.000 rs8106929 chr19:52368467 A/G cg22319618 chr22:45562946 NUP50 -0.52 -7.07 -0.36 8.85e-12 Breast cancer; LIHC trans rs875971 0.867 rs1002053 chr7:65798545 G/A cg10756647 chr7:56101905 PSPH -0.44 -6.52 -0.33 2.59e-10 Aortic root size; LIHC cis rs1008375 0.933 rs6847966 chr4:17634255 G/A cg02297831 chr4:17616191 MED28 0.51 7.95 0.39 2.76e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7937682 0.855 rs7109592 chr11:111533105 C/A cg09085632 chr11:111637200 PPP2R1B -1.04 -13.27 -0.58 1.06e-32 Primary sclerosing cholangitis; LIHC cis rs4888262 0.564 rs6564147 chr16:74622586 G/A cg01733217 chr16:74700730 RFWD3 0.83 16.02 0.65 1.79e-43 Testicular germ cell tumor; LIHC cis rs11583043 0.918 rs6693456 chr1:101424561 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.59 8.07 0.4 1.21e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs8060686 0.563 rs118005841 chr16:68157562 A/T cg05110241 chr16:68378359 PRMT7 -0.6 -6.78 -0.34 5.41e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs4474465 1.000 rs7928933 chr11:78193921 T/C cg27205649 chr11:78285834 NARS2 -0.39 -5.89 -0.3 8.99e-9 Alzheimer's disease (survival time); LIHC cis rs11123170 0.640 rs2863240 chr2:113970116 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.53 -6.76 -0.34 6.13e-11 Renal function-related traits (BUN); LIHC cis rs35110281 0.607 rs4819212 chr21:44977455 G/A cg01579765 chr21:45077557 HSF2BP -0.34 -6.52 -0.33 2.52e-10 Mean corpuscular volume; LIHC cis rs1494950 1.000 rs73797775 chr4:14976930 T/C cg12377275 chr4:15005593 CPEB2 -0.79 -6.71 -0.34 8.25e-11 Political ideology; LIHC cis rs6867032 0.527 rs4975777 chr5:1973324 G/T cg26168224 chr5:2018326 NA -0.27 -6.04 -0.31 4.06e-9 Gut microbiome composition (winter); LIHC cis rs4332037 0.707 rs62435130 chr7:1890002 C/T cg23422044 chr7:1970798 MAD1L1 -0.55 -6.66 -0.34 1.09e-10 Bipolar disorder; LIHC cis rs1577917 0.771 rs3812133 chr6:86354411 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.26 -0.49 1.06e-21 Response to antipsychotic treatment; LIHC cis rs6570726 0.791 rs379040 chr6:145889035 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.9 0.3 8.52e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7917772 0.503 rs10748825 chr10:104293609 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.05 0.58 7.17e-32 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4970988 0.556 rs2280078 chr1:150600181 C/T cg13175981 chr1:150552382 MCL1 0.49 7.06 0.36 9.41e-12 Urate levels; LIHC cis rs12477438 0.501 rs6708878 chr2:99801564 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs600806 0.683 rs10857789 chr1:110012293 C/T cg16275483 chr1:110013120 SYPL2 -0.49 -6.22 -0.32 1.42e-9 Intelligence (multi-trait analysis); LIHC cis rs600806 0.815 rs4970730 chr1:109979526 T/C cg23091122 chr1:110024289 SYPL2 -0.49 -6.49 -0.33 2.97e-10 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.791 rs2416798 chr9:123480603 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 7.95 0.39 2.83e-14 Hip circumference adjusted for BMI; LIHC cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg05025164 chr4:1340916 KIAA1530 0.45 6.54 0.33 2.27e-10 Longevity; LIHC cis rs1552244 0.608 rs9837460 chr3:10049922 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.73 0.39 1.18e-13 Alzheimer's disease; LIHC cis rs7534824 0.625 rs7414132 chr1:101526413 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.74 7.14 0.36 5.75e-12 Refractive astigmatism; LIHC cis rs11674184 0.686 rs2358039 chr2:11729606 A/G cg07314298 chr2:11723111 GREB1 -0.52 -8.36 -0.41 1.6e-15 Endometriosis; LIHC cis rs8083850 0.666 rs965943 chr18:50857430 A/G cg24270629 chr18:50823537 DCC -0.58 -8.93 -0.43 2.7e-17 Intelligence (multi-trait analysis); LIHC cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg02353165 chr6:42928485 GNMT -0.93 -14.97 -0.63 2.44e-39 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7309 0.935 rs1921309 chr2:162048975 T/A cg21518248 chr2:162101506 NA 0.46 7.09 0.36 7.91e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs655641 1.000 rs544458 chr11:85778924 C/T cg09030501 chr11:85779252 PICALM -0.48 -5.72 -0.3 2.3e-8 Platelet count; LIHC cis rs644799 0.623 rs17207890 chr11:95490754 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.62 8.28 0.41 2.86e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs8017423 0.669 rs7153190 chr14:90703904 T/G cg04374321 chr14:90722782 PSMC1 0.74 14.14 0.61 4.76e-36 Mortality in heart failure; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg27303430 chr2:227663593 IRS1 -0.52 -6.07 -0.31 3.34e-9 Systolic blood pressure; LIHC cis rs7193541 0.694 rs3896277 chr16:74480694 A/T cg01733217 chr16:74700730 RFWD3 0.46 8.33 0.41 1.96e-15 Multiple myeloma; LIHC cis rs508618 0.731 rs11805033 chr1:231546452 T/C cg06096015 chr1:231504339 EGLN1 -0.45 -7.43 -0.37 8.77e-13 Red blood cell count; LIHC cis rs16866061 0.517 rs7594223 chr2:225472985 T/C cg12698349 chr2:225449008 CUL3 0.43 6.71 0.34 7.91e-11 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg04546413 chr19:29218101 NA 0.56 10.26 0.49 1.02e-21 Methadone dose in opioid dependence; LIHC cis rs4561483 0.801 rs33631 chr16:11995387 G/C cg08843971 chr16:11963173 GSPT1 -0.42 -8.37 -0.41 1.48e-15 Testicular germ cell tumor; LIHC cis rs6546537 0.824 rs13011186 chr2:69778558 C/T cg10773587 chr2:69614142 GFPT1 -0.53 -7.23 -0.36 3.16e-12 Serum thyroid-stimulating hormone levels; LIHC cis rs1153858 1.000 rs1554521 chr15:45664189 A/T cg21132104 chr15:45694354 SPATA5L1 -0.48 -7.55 -0.38 4.07e-13 Homoarginine levels; LIHC cis rs7635838 0.617 rs184700 chr3:11293061 A/G cg00170343 chr3:11313890 ATG7 0.52 8.15 0.4 6.78e-15 HDL cholesterol; LIHC cis rs870825 0.616 rs4443323 chr4:185629805 C/A cg04058563 chr4:185651563 MLF1IP 0.78 7.46 0.37 7.42e-13 Blood protein levels; LIHC cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg07308232 chr7:1071921 C7orf50 -0.55 -8.99 -0.44 1.66e-17 Longevity;Endometriosis; LIHC cis rs7208859 0.623 rs11652631 chr17:29060766 A/G cg14067834 chr17:29058358 SUZ12P 0.68 6.79 0.34 5.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs801193 1.000 rs2707856 chr7:66211010 A/T cg18876405 chr7:65276391 NA 0.42 7.29 0.37 2.22e-12 Aortic root size; LIHC cis rs2841277 0.741 rs9672139 chr14:105408182 T/G cg21017887 chr14:105400489 NA 0.64 11.89 0.54 1.54e-27 Rheumatoid arthritis; LIHC cis rs3812111 0.665 rs517352 chr6:116429623 T/A cg08036074 chr6:116424633 NT5DC1 0.67 12.09 0.55 2.93e-28 Age-related macular degeneration; LIHC cis rs600806 0.888 rs3853498 chr1:109860144 T/C cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.31 -0.37 1.89e-12 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.953 rs12259338 chr10:969377 C/T cg26597838 chr10:835615 NA 0.96 11.79 0.54 3.72e-27 Eosinophil percentage of granulocytes; LIHC cis rs644799 0.672 rs11021347 chr11:95653494 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.77 11.22 0.52 4.31e-25 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10484885 0.824 rs112817281 chr6:90555658 G/A cg13799429 chr6:90582589 CASP8AP2 -0.7 -6.42 -0.33 4.61e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9905704 0.624 rs6503891 chr17:57065924 A/C cg12560992 chr17:57184187 TRIM37 0.68 9.8 0.47 3.72e-20 Testicular germ cell tumor; LIHC cis rs8072100 0.807 rs2175290 chr17:45479917 C/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.87 -0.3 1.03e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs116095464 0.614 rs10061564 chr5:271329 T/C cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg18357526 chr6:26021779 HIST1H4A -0.61 -8.53 -0.42 4.88e-16 Blood metabolite levels; LIHC cis rs9902453 0.838 rs8064689 chr17:28217053 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.61 0.53 1.76e-26 Coffee consumption (cups per day); LIHC cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg07092213 chr7:1199455 ZFAND2A -0.44 -6.42 -0.33 4.64e-10 Longevity;Endometriosis; LIHC cis rs12497850 0.931 rs9682444 chr3:48852639 A/G cg06212747 chr3:49208901 KLHDC8B 0.55 7.07 0.36 8.98e-12 Parkinson's disease; LIHC cis rs12478296 1.000 rs56136197 chr2:243043877 T/C cg06360820 chr2:242988706 NA -0.84 -11.72 -0.54 6.95e-27 Obesity-related traits; LIHC cis rs509477 0.718 rs273344 chr18:32603927 C/T cg23791764 chr18:32556832 MAPRE2 0.45 6.16 0.32 2.08e-9 Cerebrospinal fluid AB1-42 levels; LIHC cis rs2153535 0.540 rs9378557 chr6:8517381 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg20607798 chr8:58055168 NA 0.61 7.33 0.37 1.64e-12 Developmental language disorder (linguistic errors); LIHC trans rs12752401 0.867 rs12751548 chr1:103067463 A/G cg17681729 chr19:740608 PALM -0.43 -6.22 -0.32 1.43e-9 Resistance to antihypertensive treatment in hypertension; LIHC trans rs867371 0.929 rs7173852 chr15:82461853 A/G cg18393722 chr15:85113863 UBE2QP1 -0.44 -7.48 -0.37 6.16e-13 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs1814175 0.817 rs11493756 chr11:50017885 T/C cg15704280 chr7:45808275 SEPT13 -1.0 -23.71 -0.79 3.38e-74 Height; LIHC cis rs919433 0.680 rs7605813 chr2:198375329 C/G cg10820045 chr2:198174542 NA 0.53 8.44 0.42 9.26e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7647973 0.593 rs62262730 chr3:49808274 T/G cg03060546 chr3:49711283 APEH -0.56 -6.11 -0.31 2.74e-9 Menarche (age at onset); LIHC cis rs1267303 0.563 rs2486163 chr1:47004680 T/C cg25110126 chr1:46999211 NA 0.41 6.09 0.31 2.96e-9 Monobrow; LIHC cis rs6539267 0.748 rs1921953 chr12:106721012 C/T cg00173435 chr12:106696525 TCP11L2 0.53 6.71 0.34 7.87e-11 Tourette syndrome; LIHC cis rs10504229 0.817 rs10504230 chr8:58197150 A/G cg02290350 chr8:58132656 NA -0.37 -7.62 -0.38 2.56e-13 Developmental language disorder (linguistic errors); LIHC cis rs2479724 0.818 rs9357369 chr6:41818202 A/C cg17623882 chr6:41773611 USP49 -0.56 -8.94 -0.44 2.57e-17 Menarche (age at onset); LIHC cis rs7847628 0.666 rs2031974 chr9:123527521 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.58 8.59 0.42 3.24e-16 Birth weight; LIHC cis rs2303759 0.918 rs8107548 chr19:49870643 T/C cg22590775 chr19:49891494 CCDC155 0.48 7.91 0.39 3.67e-14 Multiple sclerosis; LIHC cis rs12477438 0.520 rs4402818 chr2:99717608 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 13.59 0.59 6.2e-34 Chronic sinus infection; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg00280220 chr17:61926910 NA 0.43 6.89 0.35 2.64e-11 Prudent dietary pattern; LIHC cis rs738321 0.756 rs12167576 chr22:38512562 G/A cg25457927 chr22:38595422 NA -0.29 -6.47 -0.33 3.49e-10 Breast cancer; LIHC cis rs8103278 0.507 rs522769 chr19:46284520 G/A cg12641515 chr19:46296257 DMWD 0.46 6.94 0.35 1.97e-11 Coronary artery disease; LIHC cis rs17685 0.784 rs1637043 chr7:75699099 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2204008 0.555 rs7310307 chr12:38107497 G/T cg26384229 chr12:38710491 ALG10B 0.81 9.5 0.46 3.89e-19 Bladder cancer; LIHC cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg14393609 chr7:65229607 NA 0.45 6.59 0.34 1.63e-10 Calcium levels; LIHC cis rs1499614 0.901 rs2178742 chr7:66197799 G/A cg12463550 chr7:65579703 CRCP 0.68 6.97 0.35 1.62e-11 Gout; LIHC cis rs7618501 0.635 rs34080578 chr3:50026029 A/C cg21467203 chr3:49911342 NA -0.44 -7.79 -0.39 7.94e-14 Intelligence (multi-trait analysis); LIHC cis rs311392 0.903 rs6993362 chr8:55089220 A/G cg20636351 chr8:55087400 NA -0.39 -8.04 -0.4 1.43e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs2439831 0.850 rs16965120 chr15:44100342 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.38 0.33 5.67e-10 Lung cancer in ever smokers; LIHC cis rs2842992 0.789 rs9355748 chr6:160194882 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.5 8.74 0.43 1.05e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs875971 0.767 rs12668005 chr7:65909021 T/C cg18252515 chr7:66147081 NA -0.44 -6.3 -0.32 9.07e-10 Aortic root size; LIHC cis rs7131987 0.903 rs10843371 chr12:29414232 G/A cg00204748 chr12:29376779 FAR2 0.42 7.89 0.39 4.23e-14 QT interval; LIHC cis rs7534824 0.583 rs6577225 chr1:101506126 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 7.2 0.36 3.9e-12 Refractive astigmatism; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13469346 chr3:53195186 PRKCD 0.42 6.25 0.32 1.22e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11148252 0.811 rs9536030 chr13:52938291 G/A cg00495681 chr13:53174319 NA -0.39 -6.29 -0.32 9.92e-10 Lewy body disease; LIHC cis rs3741404 0.672 rs4980524 chr11:63959259 A/C cg18225595 chr11:63971243 STIP1 0.63 10.41 0.49 3.21e-22 Platelet count; LIHC cis rs16828019 0.929 rs12029321 chr1:41682530 G/C cg03387723 chr1:41708464 SCMH1 -0.44 -7.23 -0.36 3.16e-12 Intelligence (multi-trait analysis); LIHC cis rs7584330 0.910 rs6737914 chr2:238393434 A/G cg14458575 chr2:238380390 NA 0.37 6.04 0.31 4.13e-9 Prostate cancer; LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg14004847 chr7:1930337 MAD1L1 -0.55 -8.31 -0.41 2.31e-15 Bipolar disorder and schizophrenia; LIHC cis rs7224737 1.000 rs9912088 chr17:40288278 T/C cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs10876993 0.928 rs1689594 chr12:58057156 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.57 -0.33 1.91e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs1419980 0.730 rs73260714 chr12:7781057 C/G cg10578777 chr12:7781093 NA -0.4 -5.83 -0.3 1.26e-8 HDL cholesterol levels; LIHC cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg11890956 chr21:40555474 PSMG1 0.57 9.52 0.46 3.26e-19 Cognitive function; LIHC cis rs875971 0.660 rs79009421 chr7:66068509 G/C cg14393609 chr7:65229607 NA -0.38 -6.03 -0.31 4.25e-9 Aortic root size; LIHC cis rs3018712 0.547 rs4930237 chr11:68414038 C/G cg16797656 chr11:68205561 LRP5 -0.45 -5.88 -0.3 9.91e-9 Total body bone mineral density; LIHC cis rs2952156 0.920 rs9303274 chr17:37836353 T/C cg00129232 chr17:37814104 STARD3 -0.56 -10.79 -0.5 1.5e-23 Asthma; LIHC cis rs240764 0.645 rs240111 chr6:101059499 C/A cg09795085 chr6:101329169 ASCC3 0.46 6.57 0.33 1.85e-10 Neuroticism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04498032 chr1:155242826 CLK2 0.38 6.39 0.33 5.38e-10 Cognitive function; LIHC cis rs933688 0.877 rs1477349 chr5:90707773 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.37 0.66 6.68e-45 Smoking behavior; LIHC cis rs7098414 0.530 rs4146515 chr10:82116602 G/A cg00277334 chr10:82204260 NA -0.54 -8.77 -0.43 8.27e-17 Post bronchodilator FEV1; LIHC cis rs9911578 0.934 rs8081967 chr17:57072701 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -9.03 -0.44 1.24e-17 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.563 rs56941405 chr20:34313426 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.76 -0.43 9.08e-17 Total cholesterol levels; LIHC cis rs763121 1.000 rs763121 chr22:38879940 C/T cg14440974 chr22:39074834 NA 0.35 5.79 0.3 1.59e-8 Menopause (age at onset); LIHC cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.47 0.33 3.38e-10 Bipolar disorder; LIHC cis rs77861329 1.000 rs352148 chr3:52208898 A/G cg08692210 chr3:52188851 WDR51A 0.8 7.69 0.38 1.56e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs17711722 0.690 rs116823227 chr7:65331001 A/G cg26939375 chr7:64535504 NA 0.44 6.09 0.31 3.11e-9 Calcium levels; LIHC cis rs5753618 0.561 rs2073857 chr22:31658281 A/G cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs61990749 0.597 rs10136053 chr14:78155205 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.59 -9.97 -0.47 9.88e-21 Fibroblast growth factor basic levels; LIHC cis rs1046896 0.594 rs8070403 chr17:80865404 A/G cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.33 0.37 1.62e-12 Glycated hemoglobin levels; LIHC cis rs7149337 0.805 rs2999355 chr14:51607084 A/G cg23942311 chr14:51606299 NA 0.35 7.33 0.37 1.7e-12 Cancer; LIHC cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg07636037 chr3:49044803 WDR6 0.74 12.17 0.55 1.48e-28 Menarche (age at onset); LIHC cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.27e-19 Initial pursuit acceleration; LIHC cis rs67981189 0.593 rs4132848 chr14:71459359 A/T cg15816911 chr14:71606274 NA 0.42 6.7 0.34 8.37e-11 Schizophrenia; LIHC trans rs911555 0.755 rs1138400 chr14:103956833 A/G cg17675199 chr6:35436792 RPL10A 0.43 8.89 0.43 3.45e-17 Intelligence (multi-trait analysis); LIHC cis rs4803468 1.000 rs3816037 chr19:41918009 C/T cg09537434 chr19:41945824 ATP5SL -1.02 -21.53 -0.76 1.31e-65 Height; LIHC cis rs35110281 0.837 rs2838340 chr21:45076373 A/G cg21573476 chr21:45109991 RRP1B -0.45 -8.78 -0.43 7.83e-17 Mean corpuscular volume; LIHC cis rs7799006 0.527 rs2159045 chr7:2207401 T/C cg04267008 chr7:1944627 MAD1L1 -0.53 -8.01 -0.4 1.81e-14 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs896854 1.000 rs896854 chr8:95960511 T/C cg13393036 chr8:95962371 TP53INP1 -0.45 -11.03 -0.51 2.02e-24 Type 2 diabetes; LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg14159672 chr1:205819179 PM20D1 0.73 10.31 0.49 7.04e-22 Menarche (age at onset); LIHC cis rs769267 0.930 rs10422819 chr19:19643028 C/A cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.47 0.37 6.62e-13 Tonsillectomy; LIHC cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs3736594 0.513 rs2384627 chr2:27774449 G/A cg27432699 chr2:27873401 GPN1 0.46 6.82 0.35 4.26e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg11890956 chr21:40555474 PSMG1 -0.57 -9.5 -0.46 3.85e-19 Cognitive function; LIHC cis rs1559088 0.600 rs7259117 chr19:33550113 G/T cg17764715 chr19:33622953 WDR88 0.55 7.29 0.37 2.14e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4742903 1.000 rs1026181 chr9:106893334 A/G cg14250997 chr9:106856677 SMC2 0.41 7.42 0.37 9.4e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2304069 0.954 rs9324640 chr5:149413186 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.94 -12.58 -0.56 4.46e-30 HIV-1 control; LIHC cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg03517284 chr6:25882590 NA -0.6 -7.28 -0.37 2.35e-12 Intelligence (multi-trait analysis); LIHC cis rs9616064 0.506 rs737135 chr22:47061791 C/T cg25730555 chr22:47059586 GRAMD4 0.36 6.02 0.31 4.6e-9 Urate levels in obese individuals; LIHC trans rs7618501 1.000 rs1049256 chr3:49763338 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.953 rs12354639 chr10:963681 G/A cg26597838 chr10:835615 NA 0.97 11.78 0.54 4.14e-27 Eosinophil percentage of granulocytes; LIHC cis rs12464559 0.649 rs3768658 chr2:152677674 T/C cg01189475 chr2:152685088 ARL5A 0.64 7.48 0.38 6.16e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs8180040 1.000 rs2159400 chr3:47375890 T/C cg27129171 chr3:47204927 SETD2 -0.64 -10.78 -0.5 1.64e-23 Colorectal cancer; LIHC cis rs77741769 0.529 rs2893876 chr12:121245158 T/C cg02419362 chr12:121203948 SPPL3 0.34 5.92 0.3 7.73e-9 Mean corpuscular volume; LIHC cis rs17685 0.672 rs6465011 chr7:75811297 T/C cg01364799 chr7:75623366 TMEM120A -0.51 -7.81 -0.39 7.2e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7100689 0.784 rs7078075 chr10:82162768 A/G cg00277334 chr10:82204260 NA -0.58 -7.47 -0.37 6.66e-13 Post bronchodilator FEV1; LIHC cis rs1055129 0.655 rs8067076 chr17:73837142 G/T cg19302996 chr17:73780495 UNK 0.6 9.74 0.47 6.25e-20 White matter hyperintensity burden; LIHC cis rs2288073 0.562 rs112892911 chr2:24590800 G/A cg06627628 chr2:24431161 ITSN2 -0.74 -9.82 -0.47 3.24e-20 Venous thromboembolism (SNP x SNP interaction); LIHC trans rs1005277 0.505 rs200935 chr10:38132810 T/A cg27523141 chr10:43048294 ZNF37B 0.39 6.86 0.35 3.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs11112613 0.713 rs73184084 chr12:105952615 T/A cg03607813 chr12:105948248 NA 0.63 12.47 0.56 1.14e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs17685 0.753 rs1637045 chr7:75703895 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.16 -0.32 2.08e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs6489882 0.867 rs6489866 chr12:113363408 A/G cg10175203 chr3:128143634 NA 0.39 6.38 0.33 5.72e-10 Chronic lymphocytic leukemia; LIHC cis rs10504229 0.679 rs78941440 chr8:58052095 A/G cg02290350 chr8:58132656 NA 0.33 7.41 0.37 1.01e-12 Developmental language disorder (linguistic errors); LIHC cis rs79149102 0.649 rs75985113 chr15:75379312 C/T cg17294928 chr15:75287854 SCAMP5 -0.5 -6.2 -0.32 1.65e-9 Lung cancer; LIHC cis rs6860806 0.507 rs156322 chr5:131653925 C/T cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 6.11e-31 Breast cancer; LIHC cis rs68170813 0.559 rs17429146 chr7:106964281 A/G cg02696742 chr7:106810147 HBP1 -0.5 -5.77 -0.3 1.75e-8 Coronary artery disease; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg23131131 chr22:24373011 LOC391322 0.51 6.52 0.33 2.47e-10 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs7072216 0.763 rs942804 chr10:100168499 C/A cg26618903 chr10:100175079 PYROXD2 -0.39 -6.25 -0.32 1.21e-9 Metabolite levels; LIHC trans rs2727020 0.637 rs1164673 chr11:49328356 C/G cg15704280 chr7:45808275 SEPT13 0.64 11.09 0.51 1.28e-24 Coronary artery disease; LIHC cis rs7178375 0.941 rs4779796 chr15:31208050 C/T cg19680485 chr15:31195859 MTMR15 -0.54 -6.0 -0.31 5.11e-9 Hypertriglyceridemia; LIHC trans rs1814175 0.619 rs10769623 chr11:49865926 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.95 0.35 1.82e-11 Height; LIHC cis rs9733 0.519 rs11587444 chr1:150722844 A/G cg17724175 chr1:150552817 MCL1 0.51 10.16 0.48 2.22e-21 Tonsillectomy; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg06618935 chr21:46677482 NA -0.3 -5.71 -0.3 2.44e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6545883 0.965 rs6718887 chr2:61727215 G/A cg15711740 chr2:61764176 XPO1 -0.43 -6.1 -0.31 2.91e-9 Tuberculosis; LIHC cis rs67311347 1.000 rs11716675 chr3:40485280 G/T cg18306943 chr3:40428807 ENTPD3 0.34 6.06 0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs7412746 0.658 rs1546376 chr1:150937661 A/G cg17724175 chr1:150552817 MCL1 0.42 8.03 0.4 1.61e-14 Melanoma; LIHC cis rs992157 0.835 rs34353396 chr2:219153982 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.78 -12.44 -0.56 1.42e-29 Colorectal cancer; LIHC cis rs9341808 0.754 rs3805885 chr6:80996751 C/G cg08355045 chr6:80787529 NA -0.32 -6.47 -0.33 3.3e-10 Sitting height ratio; LIHC cis rs9733 0.688 rs12725667 chr1:150766070 A/T cg13175981 chr1:150552382 MCL1 0.47 6.89 0.35 2.72e-11 Tonsillectomy; LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.85 -0.35 3.44e-11 Total body bone mineral density; LIHC cis rs6543140 0.964 rs1035126 chr2:103019981 C/T cg09003973 chr2:102972529 NA 0.53 6.04 0.31 4.09e-9 Blood protein levels; LIHC cis rs1008375 0.897 rs1006723 chr4:17618524 G/A cg02297831 chr4:17616191 MED28 0.49 7.75 0.39 1.08e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2075371 0.932 rs2544215 chr7:133987896 T/C cg20476274 chr7:133979776 SLC35B4 0.74 12.52 0.56 7.07e-30 Mean platelet volume; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg00280220 chr17:61926910 NA 0.44 7.07 0.36 8.7e-12 Prudent dietary pattern; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg27432699 chr2:27873401 GPN1 -0.56 -8.19 -0.41 5.17e-15 Total body bone mineral density; LIHC cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg07424592 chr7:64974309 NA 0.83 9.5 0.46 3.78e-19 Diabetic kidney disease; LIHC trans rs1005277 0.579 rs2749616 chr10:38510993 A/T cg17830980 chr10:43048298 ZNF37B -0.52 -10.07 -0.48 4.6e-21 Extrinsic epigenetic age acceleration; LIHC cis rs7020830 0.898 rs506981 chr9:37351348 A/T cg14294708 chr9:37120828 ZCCHC7 -0.93 -18.8 -0.71 1.15e-54 Schizophrenia; LIHC cis rs4700695 0.719 rs27080 chr5:65442271 A/G cg21114390 chr5:65439923 SFRS12 -0.59 -8.61 -0.42 2.72e-16 Facial morphology (factor 19); LIHC cis rs5769765 0.874 rs11703411 chr22:50258751 G/A cg02269571 chr22:50332266 NA 0.61 8.65 0.42 2.06e-16 Schizophrenia; LIHC cis rs7707921 0.767 rs226202 chr5:81571669 C/T cg15871215 chr5:81402204 ATG10 0.7 8.44 0.42 8.92e-16 Breast cancer; LIHC cis rs12980942 0.872 rs11879562 chr19:41804976 C/G cg25627403 chr19:41769009 HNRNPUL1 0.5 6.28 0.32 1.02e-9 Coronary artery disease; LIHC cis rs9611519 0.780 rs2235852 chr22:41661154 G/T cg03806693 chr22:41940476 POLR3H -0.44 -5.93 -0.31 7.56e-9 Neuroticism; LIHC cis rs16828019 0.852 rs3766324 chr1:41588653 A/G cg20697417 chr1:41786797 NA 0.33 6.24 0.32 1.32e-9 Intelligence (multi-trait analysis); LIHC cis rs1843834 0.539 rs3912999 chr2:225390089 C/T cg12698349 chr2:225449008 CUL3 0.68 10.65 0.5 4.44e-23 IgE levels in asthmatics (D.p. specific); LIHC cis rs2625529 0.761 rs972028 chr15:72173092 C/T cg16672083 chr15:72433130 SENP8 -0.3 -5.85 -0.3 1.13e-8 Red blood cell count; LIHC cis rs60871478 0.645 rs111968669 chr7:856683 C/T cg13798912 chr7:905769 UNC84A -0.55 -6.72 -0.34 7.39e-11 Cerebrospinal P-tau181p levels; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg11034861 chr16:67194079 TRADD;FBXL8 0.55 6.9 0.35 2.49e-11 Hepatitis; LIHC trans rs11098499 0.866 rs12499602 chr4:120284387 T/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs4975709 0.569 rs4975743 chr5:1859941 G/T cg15595755 chr5:1867978 NA 0.4 7.92 0.39 3.35e-14 Cardiovascular disease risk factors; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.31 0.52 2.06e-25 Prudent dietary pattern; LIHC cis rs769267 1.000 rs8103197 chr19:19443466 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -9.87 -0.47 2.26e-20 Tonsillectomy; LIHC cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg12792011 chr19:58661915 ZNF329 0.96 7.98 0.4 2.18e-14 Cholesterol, total; LIHC cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.1 -0.31 2.91e-9 Calcium levels; LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg12016809 chr21:47604291 C21orf56 -0.47 -7.33 -0.37 1.71e-12 Testicular germ cell tumor; LIHC cis rs2380220 0.720 rs9400397 chr6:95980623 C/A cg04719120 chr6:96025338 MANEA 0.55 6.49 0.33 3.03e-10 Behavioural disinhibition (generation interaction); LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg00280220 chr17:61926910 NA 0.43 6.79 0.34 4.99e-11 Prudent dietary pattern; LIHC cis rs240764 0.594 rs7356804 chr6:101078438 A/G cg09795085 chr6:101329169 ASCC3 0.41 5.91 0.3 8.43e-9 Neuroticism; LIHC cis rs17253792 0.822 rs10135426 chr14:56054644 A/G cg01858014 chr14:56050164 KTN1 -0.74 -8.25 -0.41 3.55e-15 Putamen volume; LIHC cis rs651907 0.557 rs34181125 chr3:101490278 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.83 0.51 1.03e-23 Colorectal cancer; LIHC cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.46 6.46 0.33 3.53e-10 Schizophrenia; LIHC cis rs6088590 1.000 rs6087632 chr20:33407704 A/C cg24642439 chr20:33292090 TP53INP2 0.77 10.43 0.49 2.66e-22 Coronary artery disease; LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg00280220 chr17:61926910 NA -0.39 -6.13 -0.31 2.46e-9 Prudent dietary pattern; LIHC cis rs4474465 0.646 rs7936011 chr11:78275931 G/T cg27205649 chr11:78285834 NARS2 0.48 7.57 0.38 3.6e-13 Alzheimer's disease (survival time); LIHC trans rs1005277 0.579 rs2472178 chr10:38384750 T/C cg17830980 chr10:43048298 ZNF37B -0.53 -10.74 -0.5 2.25e-23 Extrinsic epigenetic age acceleration; LIHC cis rs919433 0.680 rs3792159 chr2:198403697 A/G cg10820045 chr2:198174542 NA -0.53 -8.33 -0.41 1.96e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2050392 1.000 rs2253585 chr10:30696503 C/T cg25182066 chr10:30743637 MAP3K8 -0.44 -7.01 -0.35 1.28e-11 Inflammatory bowel disease; LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg22963979 chr7:1858916 MAD1L1 -0.44 -6.95 -0.35 1.8e-11 Bipolar disorder and schizophrenia; LIHC cis rs68170813 0.559 rs6967745 chr7:106850548 G/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs6456156 0.586 rs2345753 chr6:167484344 T/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.51 -0.42 5.66e-16 Primary biliary cholangitis; LIHC cis rs2758596 0.826 rs2251615 chr1:156202300 C/T cg24450063 chr1:156163899 SLC25A44 1.01 10.6 0.5 7.13e-23 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs3796352 0.881 rs35385050 chr3:52997945 C/A cg07884673 chr3:53033167 SFMBT1 0.91 6.58 0.34 1.8e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs892961 0.932 rs7208336 chr17:75412932 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs6570726 0.577 rs399502 chr6:145805874 A/G cg23711669 chr6:146136114 FBXO30 0.58 7.95 0.39 2.73e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 1.000 rs2065001 chr1:67486509 C/G cg08660285 chr1:67390436 MIER1;WDR78 0.95 15.76 0.65 1.9e-42 Lymphocyte percentage of white cells; LIHC cis rs7909074 0.531 rs879343 chr10:45400707 G/T cg04218760 chr10:45406644 TMEM72 -0.19 -5.76 -0.3 1.88e-8 Mean corpuscular volume; LIHC cis rs1559088 0.847 rs7254758 chr19:33608047 T/A cg17764715 chr19:33622953 WDR88 0.45 6.59 0.34 1.68e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4474465 0.850 rs10899552 chr11:78262262 G/A cg27205649 chr11:78285834 NARS2 0.42 6.25 0.32 1.24e-9 Alzheimer's disease (survival time); LIHC cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg03264133 chr6:25882463 NA 0.56 8.23 0.41 4e-15 Blood metabolite levels; LIHC cis rs4713118 0.662 rs9468271 chr6:28024570 A/G cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs2204008 0.837 rs11183232 chr12:37941053 A/G cg26384229 chr12:38710491 ALG10B 0.82 10.49 0.49 1.62e-22 Bladder cancer; LIHC cis rs4706831 0.663 rs1984242 chr6:81051245 A/G cg08355045 chr6:80787529 NA 0.34 7.02 0.35 1.19e-11 Joint mobility (Beighton score); LIHC cis rs9549367 0.826 rs9549710 chr13:113898064 A/C cg18105134 chr13:113819100 PROZ -0.67 -11.48 -0.53 5.03e-26 Platelet distribution width; LIHC cis rs1670533 0.932 rs13106586 chr4:1054182 G/A cg27284194 chr4:1044797 NA 0.6 8.97 0.44 1.94e-17 Recombination rate (females); LIHC cis rs7216064 1.000 rs8074078 chr17:65838743 A/C cg12091567 chr17:66097778 LOC651250 -0.65 -9.53 -0.46 2.91e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg18654377 chr3:49208889 KLHDC8B -0.48 -5.77 -0.3 1.75e-8 Menarche (age at onset); LIHC trans rs875971 0.964 rs778723 chr7:65829497 T/C cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg09222892 chr1:25734099 RHCE 0.48 9.06 0.44 1.02e-17 Erythrocyte sedimentation rate; LIHC cis rs10504229 0.679 rs11783557 chr8:58030644 A/G cg02290350 chr8:58132656 NA 0.31 7.17 0.36 4.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs1113500 0.933 rs1414674 chr1:108625947 A/G cg06207961 chr1:108661230 NA 0.38 7.45 0.37 7.46e-13 Growth-regulated protein alpha levels; LIHC cis rs4927850 1.000 rs7627868 chr3:195753473 A/T cg01181863 chr3:195395398 SDHAP2 -0.5 -6.5 -0.33 2.81e-10 Pancreatic cancer; LIHC cis rs3096299 0.685 rs4785568 chr16:89553707 A/G cg02034447 chr16:89574710 SPG7 0.46 7.07 0.36 8.75e-12 Multiple myeloma (IgH translocation); LIHC cis rs13108904 0.936 rs4974540 chr4:1213463 C/T cg13395646 chr4:1353034 KIAA1530 -0.43 -6.36 -0.33 6.34e-10 Obesity-related traits; LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg00091569 chr3:40428383 ENTPD3 0.4 6.79 0.34 4.86e-11 Renal cell carcinoma; LIHC cis rs600806 0.778 rs10776698 chr1:110013630 C/T cg11161837 chr1:110010384 SYPL2 0.45 6.25 0.32 1.21e-9 Intelligence (multi-trait analysis); LIHC cis rs780096 0.527 rs12471703 chr2:27738854 C/T cg21747090 chr2:27597821 SNX17 -0.41 -5.98 -0.31 5.55e-9 Total body bone mineral density; LIHC cis rs2836950 0.565 rs2150413 chr21:40614878 C/T cg06238570 chr21:40685208 BRWD1 -0.43 -6.97 -0.35 1.64e-11 Menarche (age at onset); LIHC cis rs11098499 0.754 rs11098502 chr4:120252063 T/A cg09307838 chr4:120376055 NA 0.71 11.02 0.51 2.19e-24 Corneal astigmatism; LIHC cis rs67311347 1.000 rs7636719 chr3:40432084 C/T cg16822855 chr3:40428330 ENTPD3 0.33 5.97 0.31 5.81e-9 Renal cell carcinoma; LIHC cis rs12701220 0.947 rs1007765 chr7:1032805 G/C cg04498913 chr7:1135747 C7orf50 0.39 5.85 0.3 1.14e-8 Bronchopulmonary dysplasia; LIHC cis rs2380220 0.872 rs66723559 chr6:95956338 T/C cg15832292 chr6:96025679 MANEA -0.6 -6.65 -0.34 1.16e-10 Behavioural disinhibition (generation interaction); LIHC cis rs9811920 0.638 rs2452321 chr3:99638836 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.49 -6.91 -0.35 2.37e-11 Axial length; LIHC cis rs6582630 0.555 rs11182202 chr12:38476451 C/G cg26384229 chr12:38710491 ALG10B 0.69 9.62 0.46 1.47e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs9611565 1.000 rs9611565 chr22:41767486 T/C cg03806693 chr22:41940476 POLR3H -0.92 -10.86 -0.51 8.58e-24 Vitiligo; LIHC cis rs4555082 0.874 rs760270 chr14:105737785 A/G cg06808227 chr14:105710500 BRF1 -0.55 -7.17 -0.36 4.57e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs796364 0.760 rs2881594 chr2:201026183 T/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.66 -0.34 1.13e-10 Schizophrenia; LIHC cis rs655641 1.000 rs669556 chr11:85781322 A/G cg09030501 chr11:85779252 PICALM 0.49 5.74 0.3 2.04e-8 Platelet count; LIHC cis rs28530618 0.603 rs750401 chr20:31246638 G/C cg13636640 chr20:31349939 DNMT3B -0.42 -5.85 -0.3 1.17e-8 Birth weight; LIHC cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg11764359 chr7:65958608 NA 0.6 6.38 0.33 5.71e-10 Diabetic kidney disease; LIHC cis rs7520050 0.966 rs4660321 chr1:46366760 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.79 0.3 1.58e-8 Red blood cell count;Reticulocyte count; LIHC cis rs763121 0.962 rs5757130 chr22:38937794 G/A cg06022373 chr22:39101656 GTPBP1 0.6 11.13 0.52 8.91e-25 Menopause (age at onset); LIHC cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg05552183 chr6:42928497 GNMT 0.68 10.09 0.48 3.86e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7927592 0.956 rs12274114 chr11:68255577 A/C cg16797656 chr11:68205561 LRP5 0.54 8.54 0.42 4.44e-16 Total body bone mineral density; LIHC cis rs796364 1.000 rs796364 chr2:200716119 C/A cg23649088 chr2:200775458 C2orf69 0.49 5.8 0.3 1.48e-8 Schizophrenia; LIHC cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg18404041 chr3:52824283 ITIH1 -0.56 -8.97 -0.44 1.95e-17 Bipolar disorder; LIHC cis rs11583043 1.000 rs7521424 chr1:101475901 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.83 0.3 1.3e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs10779751 0.734 rs2791658 chr1:11127871 A/G cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs4742903 0.875 rs7037174 chr9:106924871 C/T cg14250997 chr9:106856677 SMC2 0.35 5.98 0.31 5.54e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1499614 0.831 rs3800822 chr7:66147149 A/G cg12463550 chr7:65579703 CRCP -0.66 -6.92 -0.35 2.21e-11 Gout; LIHC cis rs10193935 0.901 rs10175378 chr2:42456267 A/C cg27598129 chr2:42591480 NA -0.71 -10.37 -0.49 4.43e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs67311347 0.955 rs6764102 chr3:40378153 C/G cg09455208 chr3:40491958 NA 0.33 6.51 0.33 2.63e-10 Renal cell carcinoma; LIHC cis rs10089 0.953 rs1985268 chr5:127375931 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.67 0.34 1.01e-10 Ileal carcinoids; LIHC cis rs35883536 0.566 rs4908086 chr1:101088124 C/T cg14515779 chr1:101123966 NA -0.58 -10.74 -0.5 2.15e-23 Monocyte count; LIHC trans rs79976124 0.837 rs12201218 chr6:66653619 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.62 -6.69 -0.34 9.05e-11 Type 2 diabetes; LIHC cis rs67311347 0.955 rs1129200 chr3:40532257 T/C cg09455208 chr3:40491958 NA 0.37 7.11 0.36 6.66e-12 Renal cell carcinoma; LIHC cis rs7666738 0.830 rs1593572 chr4:98979322 A/G cg05340658 chr4:99064831 C4orf37 -0.72 -12.98 -0.57 1.37e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs688020 1.000 rs673500 chr7:4229445 C/G cg02004499 chr7:4244250 SDK1 -0.41 -7.78 -0.39 8.82e-14 Liver fibrosis in pediatric non-alcoholic fatty acid liver disease; LIHC cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.54 -7.67 -0.38 1.86e-13 Bipolar disorder; LIHC cis rs6831352 0.918 rs29001199 chr4:100053891 A/G cg12011299 chr4:100065546 ADH4 -0.61 -9.97 -0.47 1.02e-20 Alcohol dependence; LIHC cis rs1664789 0.587 rs697112 chr5:53260679 A/G ch.5.1024479R chr5:53302184 ARL15 0.43 6.76 0.34 6.04e-11 Waist circumference adjusted for body mass index; LIHC cis rs10411936 0.712 rs8100755 chr19:16593415 G/A cg10248733 chr19:16607483 C19orf44;CALR3 0.51 6.81 0.35 4.36e-11 White blood cell count;Multiple sclerosis; LIHC cis rs941873 0.838 rs2233713 chr10:81107135 A/C cg09469691 chr10:81107165 PPIF 0.73 11.34 0.52 1.62e-25 Height; LIHC cis rs1395 0.744 rs11679220 chr2:27476378 G/A cg23587288 chr2:27483067 SLC30A3 -0.34 -6.32 -0.32 8e-10 Blood metabolite levels; LIHC cis rs8062405 0.722 rs3785354 chr16:28550667 C/T cg00204512 chr16:28754710 NA 0.4 7.03 0.36 1.11e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23260799 chr11:451101 PTDSS2 0.5 7.64 0.38 2.24e-13 Pancreatic cancer; LIHC cis rs2274273 0.712 rs9806049 chr14:55525589 C/A cg01864836 chr14:55583639 NA -0.38 -6.52 -0.33 2.53e-10 Protein biomarker; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01584634 chr11:72525302 ATG16L2 0.5 6.18 0.32 1.85e-9 Hepatitis; LIHC cis rs477692 0.870 rs475250 chr10:131412558 C/G cg05714579 chr10:131428358 MGMT 0.5 8.45 0.42 8.59e-16 Response to temozolomide; LIHC cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg06466757 chr4:1255808 NA -0.35 -5.89 -0.3 9.43e-9 Obesity-related traits; LIHC cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg10802521 chr3:52805072 NEK4 -0.43 -7.15 -0.36 5.18e-12 Bipolar disorder; LIHC cis rs2239547 0.657 rs2276817 chr3:52860936 C/T cg11645453 chr3:52864694 ITIH4 0.34 8.83 0.43 5.49e-17 Schizophrenia; LIHC cis rs11676348 0.774 rs57545959 chr2:219047718 A/G cg00012203 chr2:219082015 ARPC2 0.51 6.7 0.34 8.4e-11 Ulcerative colitis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18618936 chr12:122255346 SETD1B 0.45 6.45 0.33 3.79e-10 Longevity; LIHC cis rs2075371 1.000 rs1862050 chr7:133980999 T/C cg11752832 chr7:134001865 SLC35B4 0.52 7.84 0.39 5.89e-14 Mean platelet volume; LIHC cis rs9646954 0.560 rs4149507 chr2:101032745 C/T cg14675211 chr2:100938903 LONRF2 0.5 7.64 0.38 2.2e-13 Intelligence (multi-trait analysis); LIHC trans rs2832077 0.883 rs11702413 chr21:30188395 A/C cg14791747 chr16:20752902 THUMPD1 0.46 6.1 0.31 2.93e-9 Cognitive test performance; LIHC cis rs10751667 0.577 rs7946461 chr11:974035 A/G ch.11.42038R chr11:967971 AP2A2 0.56 10.2 0.48 1.73e-21 Alzheimer's disease (late onset); LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.12 0.4 8.4e-15 Height; LIHC cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg21280719 chr6:42927975 GNMT -0.36 -7.88 -0.39 4.27e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3824867 0.881 rs4752829 chr11:47396654 G/A cg20307385 chr11:47447363 PSMC3 -0.53 -7.06 -0.36 9.62e-12 Mean corpuscular hemoglobin; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg16822855 chr3:40428330 ENTPD3 0.33 5.96 0.31 6.36e-9 Renal cell carcinoma; LIHC cis rs7552404 1.000 rs11161511 chr1:76210477 A/G cg22875332 chr1:76189707 ACADM -0.5 -7.63 -0.38 2.31e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9660992 0.573 rs1172158 chr1:205208948 G/A cg21545522 chr1:205238299 TMCC2 0.37 7.1 0.36 7.18e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs7508 0.511 rs2237853 chr8:17877880 G/A cg01800426 chr8:17659068 MTUS1 -0.43 -6.19 -0.32 1.67e-9 Atrial fibrillation; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20451802 chr7:132937811 EXOC4 -0.42 -6.1 -0.31 2.9e-9 Calcium levels; LIHC cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs597539 0.652 rs546382 chr11:68704264 C/T cg04772025 chr11:68637568 NA 0.49 6.31 0.32 8.85e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs55665837 0.540 rs10128681 chr11:14701576 T/C cg25251204 chr11:14927456 NA 0.41 5.87 0.3 1.03e-8 Vitamin D levels; LIHC cis rs17539620 0.628 rs62432730 chr6:154830717 G/A cg17771515 chr6:154831774 CNKSR3 0.59 6.25 0.32 1.24e-9 Lipoprotein (a) levels; LIHC cis rs4423214 0.515 rs4944042 chr11:71118788 C/A cg05163923 chr11:71159392 DHCR7 0.63 9.33 0.45 1.35e-18 Vitamin D levels; LIHC cis rs6867032 1.000 rs4398675 chr5:2015816 G/A cg26168224 chr5:2018326 NA 0.31 7.54 0.38 4.32e-13 Gut microbiome composition (winter); LIHC cis rs727505 0.954 rs67870530 chr7:124591878 A/G cg23710748 chr7:124431027 NA -0.33 -5.97 -0.31 5.93e-9 Lewy body disease; LIHC cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg26119090 chr2:26468346 HADHA;HADHB 1.09 17.04 0.68 1.44e-47 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.628 rs72700895 chr1:150626029 C/T cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs2839186 0.967 rs17176131 chr21:47705237 T/C cg09417038 chr21:47716443 C21orf57 -0.5 -7.34 -0.37 1.55e-12 Testicular germ cell tumor; LIHC cis rs4975616 0.869 rs465498 chr5:1325803 A/G cg06550200 chr5:1325588 CLPTM1L -0.65 -10.64 -0.5 5.01e-23 Lung cancer; LIHC cis rs10193935 0.901 rs10169971 chr2:42602189 G/A cg27598129 chr2:42591480 NA -0.74 -11.34 -0.52 1.58e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg22907277 chr7:1156413 C7orf50 0.53 7.91 0.39 3.69e-14 Longevity;Endometriosis; LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg12516959 chr21:47718080 NA 0.36 5.96 0.31 6.42e-9 Testicular germ cell tumor; LIHC cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg27572855 chr1:25598939 RHD 0.4 8.79 0.43 7.63e-17 Erythrocyte sedimentation rate; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12635664 chr10:71930586 SAR1A -0.39 -6.09 -0.31 2.98e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs8177253 0.530 rs8177177 chr3:133463195 A/G cg12373951 chr3:133503437 NA 0.42 6.88 0.35 2.94e-11 Iron status biomarkers; LIHC cis rs7116495 1.000 rs661242 chr11:71579229 T/C cg26138937 chr11:71823887 C11orf51 0.69 6.83 0.35 3.91e-11 Severe influenza A (H1N1) infection; LIHC cis rs17685 0.712 rs1859794 chr7:75821544 G/A cg01364799 chr7:75623366 TMEM120A -0.51 -7.86 -0.39 4.9e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1018836 0.923 rs12680211 chr8:91633434 C/T cg16814680 chr8:91681699 NA -0.63 -10.19 -0.48 1.78e-21 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7561273 0.586 rs11892283 chr2:24317850 T/C cg06627628 chr2:24431161 ITSN2 -0.44 -5.89 -0.3 9.14e-9 Quantitative traits; LIHC cis rs7312933 0.558 rs4768402 chr12:42755576 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.25 -0.41 3.44e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs992157 0.835 rs10932769 chr2:219147245 T/G cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.18 -0.55 1.4e-28 Colorectal cancer; LIHC cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.02 -0.44 1.42e-17 Bipolar disorder; LIHC cis rs1448094 0.512 rs6539931 chr12:86247473 C/T cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC cis rs9549328 0.800 rs1317507 chr13:113631780 G/T cg18289306 chr13:113640169 MCF2L 0.4 6.57 0.33 1.85e-10 Systolic blood pressure; LIHC cis rs1113500 0.897 rs4628530 chr1:108638708 T/G cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.87e-12 Growth-regulated protein alpha levels; LIHC cis rs2758596 1.000 rs2736608 chr1:156180349 T/A cg25208724 chr1:156163844 SLC25A44 0.73 7.35 0.37 1.49e-12 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.29 0.37 2.1e-12 Height; LIHC cis rs1941023 0.584 rs6591578 chr11:60158649 G/A cg08716584 chr11:60157161 MS4A7 -0.38 -8.35 -0.41 1.71e-15 Congenital heart disease (maternal effect); LIHC cis rs6594499 0.872 rs10055177 chr5:110450584 T/G cg04022379 chr5:110408740 TSLP 0.5 8.29 0.41 2.69e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs12928939 0.815 rs12448022 chr16:71724369 T/C cg03805757 chr16:71968109 PKD1L3 -0.64 -7.11 -0.36 6.73e-12 Post bronchodilator FEV1; LIHC cis rs8072100 0.840 rs56952963 chr17:45493826 T/C cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.36 -5.83 -0.3 1.3e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2832191 0.791 rs57721945 chr21:30498744 T/C cg24692254 chr21:30365293 RNF160 -0.59 -10.28 -0.49 8.89e-22 Dental caries; LIHC cis rs2974760 0.606 rs6600143 chr16:201389 A/C cg08400316 chr16:204221 HBZ -0.76 -13.15 -0.58 3.05e-32 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs4555082 0.834 rs2975217 chr14:105710238 A/C cg10792982 chr14:105748885 BRF1 0.44 5.92 0.3 7.76e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9916302 0.904 rs12952384 chr17:37669536 T/C cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC cis rs17685 0.753 rs2302438 chr7:75677065 C/A cg01364799 chr7:75623366 TMEM120A -0.5 -7.54 -0.38 4.22e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3903072 0.528 rs7928652 chr11:65580228 A/C cg00576331 chr11:65640516 EFEMP2 -0.4 -5.72 -0.3 2.39e-8 Breast cancer; LIHC cis rs7107174 1.000 rs2512544 chr11:77986371 A/T cg02023728 chr11:77925099 USP35 0.5 9.49 0.46 4.13e-19 Testicular germ cell tumor; LIHC cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg20887711 chr4:1340912 KIAA1530 0.8 12.89 0.57 2.89e-31 Longevity; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08460793 chr16:11836374 TXNDC11 0.39 6.48 0.33 3.13e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs72653721 0.838 rs72653724 chr6:11028293 C/T cg13562911 chr6:11044106 ELOVL2 0.51 7.38 0.37 1.24e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs7666738 0.546 rs13149516 chr4:98913030 T/A cg05340658 chr4:99064831 C4orf37 0.49 6.51 0.33 2.66e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs703842 1.000 rs1599932 chr12:58177943 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.3 0.61 1.07e-36 Multiple sclerosis; LIHC cis rs1707322 0.826 rs10890349 chr1:46249955 T/C cg06784218 chr1:46089804 CCDC17 0.38 6.84 0.35 3.67e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10660249 chr9:5833007 ERMP1 0.44 6.62 0.34 1.36e-10 Pancreatic cancer; LIHC cis rs72949976 1.000 rs6747328 chr2:214032156 C/G cg08319019 chr2:214017104 IKZF2 -0.61 -6.54 -0.33 2.29e-10 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs11077998 0.967 rs4789788 chr17:80510285 C/T cg10255544 chr17:80519551 FOXK2 -0.5 -9.17 -0.44 4.64e-18 Reticulocyte fraction of red cells; LIHC cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs919433 0.963 rs1896857 chr2:198164530 A/G cg10820045 chr2:198174542 NA -0.58 -9.8 -0.47 3.76e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs35883536 0.967 rs9433740 chr1:101133985 G/A cg14515779 chr1:101123966 NA 0.67 13.04 0.58 8.23e-32 Monocyte count; LIHC cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg20891558 chr2:74357851 NA 0.79 16.55 0.67 1.35e-45 Gestational age at birth (maternal effect); LIHC cis rs10751667 0.600 rs10902266 chr11:1005697 G/T cg06064525 chr11:970664 AP2A2 -0.44 -10.82 -0.5 1.2e-23 Alzheimer's disease (late onset); LIHC cis rs8017423 0.967 rs8022531 chr14:90729931 T/C cg14092571 chr14:90743983 NA -0.41 -6.53 -0.33 2.34e-10 Mortality in heart failure; LIHC cis rs7618501 0.633 rs6792892 chr3:49995518 T/C cg21467203 chr3:49911342 NA -0.44 -7.91 -0.39 3.57e-14 Intelligence (multi-trait analysis); LIHC cis rs6121246 0.821 rs7265413 chr20:30317923 G/A cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg00149659 chr3:10157352 C3orf10 0.61 5.94 0.31 7.06e-9 Alzheimer's disease; LIHC cis rs507080 0.769 rs570952 chr11:118500193 T/C cg04173919 chr11:118528438 PHLDB1 0.32 5.79 0.3 1.59e-8 Serum metabolite levels; LIHC cis rs13191362 1.000 rs13207239 chr6:163008772 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 -1.14 -12.16 -0.55 1.66e-28 Platelet count; LIHC trans rs6951245 0.638 rs74976697 chr7:1160505 C/T cg13565492 chr6:43139072 SRF -0.79 -6.79 -0.34 5.05e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3770081 1.000 rs58365138 chr2:86213105 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.79 -8.14 -0.4 7.46e-15 Facial emotion recognition (sad faces); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01779903 chr5:148205646 ADRB2 0.35 6.24 0.32 1.31e-9 Calcium levels; LIHC cis rs11760633 0.672 rs10950377 chr7:1835894 C/G cg23422044 chr7:1970798 MAD1L1 0.38 5.92 0.3 7.87e-9 Coronary artery disease; LIHC cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg13395646 chr4:1353034 KIAA1530 -0.49 -8.04 -0.4 1.52e-14 Obesity-related traits; LIHC cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg05665937 chr4:1216051 CTBP1 0.45 6.29 0.32 9.72e-10 Obesity-related traits; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg18538332 chr22:24372958 LOC391322 -0.66 -10.01 -0.48 7.17e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1552244 0.572 rs6783705 chr3:10164783 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs11229555 0.645 rs61905183 chr11:58228463 T/A cg15696309 chr11:58395628 NA -0.64 -7.36 -0.37 1.38e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9640161 0.830 rs36069544 chr7:150061538 G/A cg10018233 chr7:150070692 REPIN1 0.68 12.3 0.55 5.01e-29 Blood protein levels;Circulating chemerin levels; LIHC cis rs1577917 0.958 rs10944147 chr6:86550786 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.18 -0.52 6.29e-25 Response to antipsychotic treatment; LIHC cis rs1670533 1.000 rs676561 chr4:1083112 C/T cg27284194 chr4:1044797 NA 0.61 8.98 0.44 1.91e-17 Recombination rate (females); LIHC trans rs561341 0.941 rs736678 chr17:30347423 G/T cg20587970 chr11:113659929 NA -1.44 -11.88 -0.54 1.79e-27 Hip circumference adjusted for BMI; LIHC cis rs3892630 0.878 rs66788054 chr19:33190146 G/T cg22980127 chr19:33182716 NUDT19 1.04 12.27 0.55 6.08e-29 Red blood cell traits; LIHC cis rs11628318 0.539 rs57749886 chr14:103095652 C/T cg23461800 chr14:103021989 NA -0.38 -5.78 -0.3 1.69e-8 Platelet count; LIHC cis rs4742903 1.000 rs7854630 chr9:106875277 A/C cg14250997 chr9:106856677 SMC2 -0.43 -7.59 -0.38 2.97e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.47e-18 Bipolar disorder; LIHC cis rs17685 0.753 rs1637037 chr7:75692927 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.34 -0.32 7.24e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2991971 0.967 rs2275276 chr1:45973928 C/T cg05343316 chr1:45956843 TESK2 -0.42 -6.19 -0.32 1.69e-9 High light scatter reticulocyte count; LIHC cis rs13223928 0.516 rs11763949 chr7:3150279 A/C cg19214707 chr7:3157722 NA -0.39 -7.1 -0.36 7.28e-12 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs12586317 0.547 rs78609489 chr14:35497285 T/C cg05294307 chr14:35346193 BAZ1A -0.52 -7.7 -0.38 1.51e-13 Psoriasis; LIHC cis rs3812831 0.654 rs9314900 chr13:114937618 A/C cg06611532 chr13:114900021 NA 0.38 6.93 0.35 2.06e-11 Schizophrenia; LIHC cis rs9517320 0.515 rs4772099 chr13:99196121 A/C cg07423050 chr13:99094983 FARP1 -0.52 -9.15 -0.44 5.28e-18 Longevity; LIHC cis rs2066819 1.000 rs11575232 chr12:56744422 G/A cg26734620 chr12:56694298 CS 1.21 10.14 0.48 2.67e-21 Psoriasis vulgaris; LIHC cis rs6121246 0.697 rs6060912 chr20:30325755 C/A cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC cis rs7020830 0.861 rs13295981 chr9:37330067 C/T cg14294708 chr9:37120828 ZCCHC7 1.17 26.54 0.82 4.52e-85 Schizophrenia; LIHC cis rs4650994 0.593 rs12040058 chr1:178503557 C/G cg05350800 chr1:178550844 NA -0.3 -6.42 -0.33 4.65e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7399018 0.739 rs10747608 chr12:51616582 A/G cg25754956 chr12:51612065 POU6F1 0.68 9.96 0.47 1.12e-20 Cisplatin-induced ototoxicity; LIHC cis rs919433 0.783 rs787979 chr2:198242868 A/T cg03934865 chr2:198174659 NA 0.52 7.88 0.39 4.35e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg12042659 chr19:58951599 ZNF132 0.37 6.31 0.32 8.45e-10 Uric acid clearance; LIHC trans rs9929218 0.954 rs34097984 chr16:68824148 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.26 -0.41 3.28e-15 Colorectal cancer; LIHC cis rs7617773 0.817 rs11709691 chr3:48303669 A/G cg11946769 chr3:48343235 NME6 0.91 11.37 0.52 1.3e-25 Coronary artery disease; LIHC cis rs16912285 0.688 rs59246618 chr11:24315201 G/T ch.11.24196551F chr11:24239977 NA 0.79 10.81 0.5 1.31e-23 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs11792861 0.591 rs2282206 chr9:111746267 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.68 11.28 0.52 2.71e-25 Menarche (age at onset); LIHC cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg20090690 chr10:134436459 INPP5A 0.44 5.76 0.3 1.84e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10878977 0.565 rs7964397 chr12:69811876 C/A cg17330252 chr12:69809627 NA 0.38 5.97 0.31 6.01e-9 Colorectal cancer; LIHC cis rs910316 0.737 rs175043 chr14:75471803 G/A cg11812906 chr14:75593930 NEK9 -0.76 -14.34 -0.61 7.29e-37 Height; LIHC cis rs116095464 0.510 rs60844864 chr5:267000 A/G cg22496380 chr5:211416 CCDC127 -1.02 -10.45 -0.49 2.25e-22 Breast cancer; LIHC cis rs6088580 0.543 rs4911158 chr20:33239512 T/C cg07148914 chr20:33460835 GGT7 -0.51 -7.21 -0.36 3.56e-12 Glomerular filtration rate (creatinine); LIHC trans rs7246657 0.943 rs13345116 chr19:37847098 A/T cg10208301 chr11:6592745 DNHD1 0.48 6.96 0.35 1.71e-11 Coronary artery calcification; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05704155 chr1:10459140 PGD -0.42 -6.83 -0.35 3.87e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4925166 1 rs4925166 chr17:18210810 T/G cg26763362 chr17:18266135 SHMT1 -0.27 -6.01 -0.31 4.65e-9 Multiple sclerosis; LIHC cis rs2072499 0.966 rs887953 chr1:156191149 T/C cg24450063 chr1:156163899 SLC25A44 1.06 18.31 0.7 1.08e-52 Testicular germ cell tumor; LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg04013166 chr16:89971882 TCF25 0.6 7.92 0.39 3.27e-14 Skin colour saturation; LIHC cis rs933688 1.000 rs6869717 chr5:90694797 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.63 0.67 6.53e-46 Smoking behavior; LIHC cis rs72781680 1.000 rs72796329 chr2:24141912 G/A cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01458420 chr20:48532416 SPATA2 -0.39 -6.04 -0.31 4.12e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs3780486 0.505 rs7868663 chr9:33141229 A/G cg20290983 chr6:43655470 MRPS18A 0.96 20.39 0.74 4.7e-61 IgG glycosylation; LIHC cis rs3820500 0.543 rs2767318 chr1:118068558 G/A cg20383390 chr1:117909022 MAN1A2 -0.45 -5.96 -0.31 6.27e-9 Pneumonia; LIHC cis rs35883536 0.647 rs2783693 chr1:101045040 C/T cg14515779 chr1:101123966 NA -0.49 -7.03 -0.36 1.16e-11 Monocyte count; LIHC cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.47 8.75 0.43 9.66e-17 Total body bone mineral density; LIHC cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg18225595 chr11:63971243 STIP1 0.64 8.12 0.4 8.72e-15 Attention deficit hyperactivity disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23861078 chr2:27435638 SLC5A6;C2orf28 0.42 6.47 0.33 3.35e-10 Cognitive function; LIHC cis rs12802244 1 rs12802244 chr11:47932666 G/A cg20135002 chr11:47629003 NA -0.45 -7.83 -0.39 6.01e-14 Neuroticism; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07385723 chr6:170065891 WDR27 0.37 6.13 0.31 2.44e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.26 -0.61 1.61e-36 Alzheimer's disease; LIHC trans rs877282 0.682 rs2265092 chr10:780293 C/T cg22713356 chr15:30763199 NA -0.74 -8.06 -0.4 1.27e-14 Uric acid levels; LIHC cis rs11864453 0.713 rs7191127 chr16:72123992 G/T cg16558253 chr16:72132732 DHX38 -0.51 -8.1 -0.4 9.86e-15 Fibrinogen levels; LIHC cis rs539514 0.690 rs528783 chr13:76319460 T/C cg04757411 chr13:76259545 LMO7 -0.47 -8.13 -0.4 7.86e-15 Type 1 diabetes; LIHC cis rs7703051 0.707 rs7730344 chr5:74587940 C/A cg19683494 chr5:74908142 NA 0.49 7.21 0.36 3.55e-12 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs11608355 0.545 rs56144717 chr12:109902304 T/C cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs2795502 0.873 rs3123753 chr10:43404899 C/T cg20628663 chr10:43360327 NA 0.45 6.72 0.34 7.41e-11 Blood protein levels; LIHC cis rs8072100 0.935 rs12150231 chr17:45717091 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 0.39 6.1 0.31 2.81e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs8103278 0.740 rs72626215 chr19:46294136 G/A cg11657440 chr19:46296263 DMWD -0.51 -7.55 -0.38 4.07e-13 Coronary artery disease; LIHC cis rs9911578 0.867 rs72628394 chr17:57121313 C/T cg05425664 chr17:57184151 TRIM37 0.58 8.71 0.43 1.36e-16 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.702 rs6500606 chr16:4502514 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 -0.46 -6.52 -0.33 2.5e-10 Schizophrenia; LIHC cis rs15676 0.783 rs4837316 chr9:131577450 A/G cg00228799 chr9:131580591 ENDOG 0.48 6.91 0.35 2.42e-11 Blood metabolite levels; LIHC trans rs7618501 0.574 rs6765484 chr3:50041313 C/T cg21659725 chr3:3221576 CRBN -0.68 -10.93 -0.51 4.57e-24 Intelligence (multi-trait analysis); LIHC cis rs651907 0.557 rs11917569 chr3:101355063 G/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 10.81 0.5 1.26e-23 Colorectal cancer; LIHC cis rs7116495 1.000 rs659513 chr11:71812411 C/T cg10381502 chr11:71823885 C11orf51 0.56 5.73 0.3 2.22e-8 Severe influenza A (H1N1) infection; LIHC cis rs8062405 1.000 rs11861174 chr16:28871989 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1371867 0.875 rs7830342 chr8:101327738 T/A cg06636551 chr8:101224915 SPAG1 -0.47 -8.71 -0.43 1.34e-16 Atrioventricular conduction; LIHC cis rs4908768 1.000 rs12122666 chr1:8741438 A/C cg25722041 chr1:8623473 RERE -0.45 -6.3 -0.32 9.41e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2153535 0.601 rs2143352 chr6:8530248 G/C cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs2228479 0.850 rs62052660 chr16:89847420 T/A cg19635926 chr16:89946313 TCF25 0.51 6.44 0.33 4.05e-10 Skin colour saturation; LIHC cis rs11229555 0.645 rs10896778 chr11:58193925 T/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6061231 0.958 rs2427305 chr20:60953749 G/C cg06026331 chr20:60912101 LAMA5 0.44 6.13 0.31 2.43e-9 Colorectal cancer; LIHC cis rs875971 0.638 rs801205 chr7:66022144 C/A cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs11030122 0.702 rs10767702 chr11:3934132 T/C cg18678763 chr11:4115507 RRM1 -0.56 -8.18 -0.4 5.53e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs12824058 0.831 rs7979497 chr12:130804706 C/T cg24838063 chr12:130822603 PIWIL1 0.65 8.96 0.44 2.11e-17 Menopause (age at onset); LIHC trans rs801193 0.591 rs2707839 chr7:66193084 A/G cg10756647 chr7:56101905 PSPH 0.46 6.93 0.35 2.1e-11 Aortic root size; LIHC cis rs796364 0.664 rs4673660 chr2:200915395 C/T cg19045956 chr2:200819837 C2orf60;C2orf47 0.38 6.41 0.33 4.79e-10 Schizophrenia; LIHC cis rs9543976 1.000 rs3818355 chr13:76196867 C/T cg01531495 chr13:76123901 UCHL3 0.49 5.8 0.3 1.48e-8 Diabetic retinopathy; LIHC cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg12310025 chr6:25882481 NA -0.52 -6.68 -0.34 9.65e-11 Intelligence (multi-trait analysis); LIHC cis rs853679 0.517 rs36078605 chr6:28078032 A/C cg16479474 chr6:28041457 NA 0.46 6.59 0.34 1.71e-10 Depression; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18016822 chr2:45838545 SRBD1 0.44 6.55 0.33 2.14e-10 Calcium levels; LIHC cis rs1865721 0.771 rs72975988 chr18:73128289 T/G cg26385618 chr18:73139727 C18orf62 -0.32 -8.5 -0.42 6.16e-16 Intelligence; LIHC cis rs55665837 1.000 rs7945167 chr11:14451820 T/G cg19336497 chr11:14380999 RRAS2 -0.44 -8.12 -0.4 8.51e-15 Vitamin D levels; LIHC cis rs10847980 0.590 rs75217947 chr12:123346177 G/C cg07706471 chr12:123319906 HIP1R 0.78 8.73 0.43 1.15e-16 Adiponectin levels; LIHC cis rs4908768 0.657 rs4908778 chr1:8804888 C/G cg20416874 chr1:8611966 RERE 0.43 6.43 0.33 4.37e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg11644478 chr21:40555479 PSMG1 0.83 10.69 0.5 3.38e-23 Cognitive function; LIHC cis rs739401 0.595 rs402806 chr11:3066432 A/G cg20651018 chr11:3035856 CARS -0.37 -6.12 -0.31 2.63e-9 Longevity; LIHC cis rs9309711 0.544 rs9309712 chr2:3491327 G/T cg10845886 chr2:3471009 TTC15 -0.4 -7.39 -0.37 1.16e-12 Neurofibrillary tangles; LIHC cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg12751644 chr20:60527061 NA -0.35 -5.87 -0.3 1.03e-8 Body mass index; LIHC cis rs875971 0.798 rs7789615 chr7:65878661 A/G cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs10791097 0.694 rs2236717 chr11:130739887 G/T cg09137382 chr11:130731461 NA 0.41 6.09 0.31 2.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs748404 0.560 rs1060939 chr15:43816917 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.38 6.29 0.32 9.8e-10 Lung cancer; LIHC cis rs11628318 0.713 rs4900543 chr14:103029024 T/C cg12046867 chr14:103022105 NA -0.57 -8.36 -0.41 1.6e-15 Platelet count; LIHC cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.81 0.57 5.88e-31 Total body bone mineral density; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05509352 chr5:142092851 NA 0.41 6.28 0.32 1e-9 Calcium levels; LIHC cis rs6089584 0.888 rs6089623 chr20:60615759 A/G cg06108461 chr20:60628389 TAF4 -1.02 -17.32 -0.68 1.11e-48 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22958951 chr11:119252637 USP2 0.44 6.59 0.34 1.67e-10 Cognitive function; LIHC trans rs1005277 0.579 rs2023351 chr10:38378814 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs11098499 0.863 rs3775841 chr4:120425777 A/C cg09307838 chr4:120376055 NA 0.78 12.19 0.55 1.27e-28 Corneal astigmatism; LIHC cis rs2066819 0.818 rs703830 chr12:56701872 T/C cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Psoriasis vulgaris; LIHC cis rs2380220 0.935 rs7748857 chr6:96001887 A/G cg04719120 chr6:96025338 MANEA 0.5 6.19 0.32 1.74e-9 Behavioural disinhibition (generation interaction); LIHC cis rs4319547 0.737 rs4758646 chr12:122946507 G/A cg23029597 chr12:123009494 RSRC2 -0.49 -6.96 -0.35 1.75e-11 Body mass index; LIHC cis rs6545883 0.931 rs9807965 chr2:61732159 T/C cg15711740 chr2:61764176 XPO1 -0.43 -6.1 -0.31 2.91e-9 Tuberculosis; LIHC trans rs2243480 1.000 rs316330 chr7:65605372 C/A cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs4665809 1.000 rs4665811 chr2:26260017 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.71 -8.61 -0.42 2.66e-16 Gut microbiome composition (summer); LIHC cis rs12464559 0.522 rs6759419 chr2:152549703 G/A cg01189475 chr2:152685088 ARL5A 0.66 7.87 0.39 4.8e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs903552 1.000 rs12907048 chr15:102003873 G/T cg00659931 chr15:102010125 PCSK6 -0.44 -5.97 -0.31 5.86e-9 Diabetic kidney disease; LIHC trans rs208520 0.874 rs208485 chr6:66925654 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.72 -7.92 -0.39 3.3e-14 Exhaled nitric oxide output; LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg09033563 chr22:24373618 LOC391322 -0.44 -6.02 -0.31 4.42e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02902865 chr1:12679132 DHRS3 0.42 6.71 0.34 7.99e-11 Cognitive function; LIHC cis rs9457247 0.663 rs9459835 chr6:167417551 G/T cg12798992 chr6:167411361 FGFR1OP 0.52 8.53 0.42 4.81e-16 Crohn's disease; LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg11766577 chr21:47581405 C21orf56 0.38 6.04 0.31 4.04e-9 Testicular germ cell tumor; LIHC cis rs9858542 0.903 rs11917431 chr3:49644012 C/T cg03060546 chr3:49711283 APEH -0.59 -7.64 -0.38 2.21e-13 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs61931739 0.534 rs12831685 chr12:34038392 C/T cg26384229 chr12:38710491 ALG10B 0.43 6.18 0.32 1.85e-9 Morning vs. evening chronotype; LIHC cis rs2635047 0.967 rs7242978 chr18:44633424 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -6.4 -0.33 5.2e-10 Educational attainment; LIHC trans rs208520 0.690 rs207094 chr6:66799009 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.13 -0.44 5.97e-18 Exhaled nitric oxide output; LIHC trans rs208520 0.690 rs7764570 chr6:66827600 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.73 -8.19 -0.4 5.21e-15 Exhaled nitric oxide output; LIHC cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg06453172 chr10:134556979 INPP5A -0.63 -7.94 -0.39 2.98e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg18538332 chr22:24372958 LOC391322 -0.64 -9.49 -0.46 4e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs546131 0.642 rs537873 chr11:34835121 A/G cg11058730 chr11:34937778 PDHX;APIP 0.66 9.66 0.46 1.13e-19 Lung disease severity in cystic fibrosis; LIHC cis rs611744 0.647 rs647907 chr8:109251374 T/C cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg05590025 chr7:65112418 INTS4L2 -0.63 -6.86 -0.35 3.18e-11 Diabetic kidney disease; LIHC cis rs826838 0.935 rs1719855 chr12:39127242 C/T cg26384229 chr12:38710491 ALG10B -0.61 -8.98 -0.44 1.87e-17 Heart rate; LIHC cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7100689 0.784 rs4934083 chr10:82116501 G/C cg01528321 chr10:82214614 TSPAN14 0.86 11.64 0.53 1.33e-26 Post bronchodilator FEV1; LIHC cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.68 0.57 1.91e-30 Alzheimer's disease; LIHC trans rs4566357 0.557 rs6707158 chr2:227911269 A/G cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.6e-9 Coronary artery disease; LIHC cis rs4759375 1.000 rs73231952 chr12:123785538 C/A cg00376283 chr12:123451042 ABCB9 -0.49 -6.31 -0.32 8.53e-10 HDL cholesterol; LIHC trans rs1814175 0.817 rs7932683 chr11:49983640 G/A cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs595982 0.527 rs73061658 chr19:49372376 G/C cg21252483 chr19:49399788 TULP2 -0.92 -10.12 -0.48 3.02e-21 Red cell distribution width; LIHC trans rs5756813 0.754 rs4820308 chr22:38176216 G/A cg19894588 chr14:64061835 NA -0.63 -8.76 -0.43 9.08e-17 Optic cup area;Vertical cup-disc ratio; LIHC cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg08219700 chr8:58056026 NA 0.5 6.39 0.33 5.5e-10 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg22907277 chr7:1156413 C7orf50 0.44 6.4 0.33 5.1e-10 Longevity;Endometriosis; LIHC cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg17971929 chr21:40555470 PSMG1 0.79 9.51 0.46 3.56e-19 Cognitive function; LIHC cis rs7116495 1.000 rs6592453 chr11:71683231 C/G cg26138937 chr11:71823887 C11orf51 -0.82 -8.17 -0.4 6.02e-15 Severe influenza A (H1N1) infection; LIHC cis rs10751667 0.600 rs1128413 chr11:1010694 C/T ch.11.42038R chr11:967971 AP2A2 0.57 10.75 0.5 2.01e-23 Alzheimer's disease (late onset); LIHC cis rs5769765 0.646 rs9616205 chr22:50309915 A/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.36 -0.45 1.07e-18 Schizophrenia; LIHC cis rs9790314 0.695 rs7637086 chr3:160836822 T/C cg03342759 chr3:160939853 NMD3 -0.72 -11.07 -0.51 1.45e-24 Morning vs. evening chronotype; LIHC cis rs2070488 0.932 rs4678604 chr3:38444273 G/A cg24069376 chr3:38537580 EXOG 0.42 7.6 0.38 2.91e-13 Electrocardiographic conduction measures; LIHC cis rs4820294 1.000 rs713835 chr22:38064650 C/T cg26138144 chr22:38071188 LGALS1 0.75 14.21 0.61 2.53e-36 Fat distribution (HIV); LIHC cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg05552183 chr6:42928497 GNMT 0.82 12.15 0.55 1.81e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs17666538 0.535 rs4338080 chr8:615598 A/G cg13264159 chr8:625131 ERICH1 -0.62 -6.28 -0.32 1.06e-9 IgG glycosylation; LIHC cis rs9858542 0.953 rs6766131 chr3:49538932 T/C cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7520050 0.966 rs7540325 chr1:46338217 A/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs10751667 0.666 rs7394958 chr11:965944 C/G ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs4555082 0.834 rs2735819 chr14:105713449 C/T cg13114125 chr14:105738426 BRF1 -0.78 -10.01 -0.48 7.62e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 0.577 rs2887951 chr3:40282104 C/G cg13409248 chr3:40428643 ENTPD3 0.38 6.03 0.31 4.32e-9 Renal cell carcinoma; LIHC cis rs7116495 0.609 rs1892920 chr11:71702431 A/G cg26138937 chr11:71823887 C11orf51 -1.28 -10.45 -0.49 2.31e-22 Severe influenza A (H1N1) infection; LIHC cis rs7677751 0.806 rs60806423 chr4:55086816 C/T cg17187183 chr4:55093834 PDGFRA 0.65 8.12 0.4 8.56e-15 Corneal astigmatism; LIHC cis rs1075232 1.000 rs12440544 chr15:32096504 C/T cg01030201 chr15:31746330 NA -0.82 -6.4 -0.33 4.98e-10 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs752010 0.714 rs10890144 chr1:42085397 G/T cg06885757 chr1:42089581 HIVEP3 0.3 6.36 0.33 6.42e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs13161895 1.000 rs35592104 chr5:179447661 A/T cg06664874 chr5:179499304 RNF130 0.58 7.16 0.36 5.09e-12 LDL cholesterol; LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg13126279 chr21:47581558 C21orf56 0.47 7.76 0.39 1.01e-13 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg05590025 chr7:65112418 INTS4L2 -0.62 -6.81 -0.35 4.45e-11 Diabetic kidney disease; LIHC cis rs10197940 0.789 rs2444256 chr2:152280365 C/T cg19508488 chr2:152266495 RIF1 0.66 10.0 0.48 8.28e-21 Lung cancer; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg00705661 chr14:93706609 BTBD7 0.5 6.31 0.32 8.57e-10 Hip circumference; LIHC cis rs75908454 1.000 rs76451345 chr6:169806527 T/C cg19338460 chr6:170058176 WDR27 -0.83 -7.47 -0.37 6.59e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs17152411 1.000 rs7089014 chr10:126590342 G/A cg07906193 chr10:126599966 NA 0.46 7.11 0.36 6.9e-12 Height; LIHC cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg11890956 chr21:40555474 PSMG1 1.07 15.36 0.64 7.19e-41 Cognitive function; LIHC cis rs4713118 0.629 rs203887 chr6:28021269 C/T cg16479474 chr6:28041457 NA 0.41 5.84 0.3 1.22e-8 Parkinson's disease; LIHC cis rs10751667 0.600 rs11246376 chr11:999622 C/T cg06064525 chr11:970664 AP2A2 -0.44 -10.75 -0.5 2.12e-23 Alzheimer's disease (late onset); LIHC cis rs6459804 0.787 rs78566714 chr7:157508951 G/A cg05731713 chr7:157510257 PTPRN2 0.24 6.52 0.33 2.47e-10 Bipolar disorder and schizophrenia; LIHC cis rs55702914 0.746 rs4850425 chr2:198152786 T/C cg03934865 chr2:198174659 NA -0.4 -5.76 -0.3 1.88e-8 Major depression and alcohol dependence; LIHC cis rs9311474 0.629 rs13081028 chr3:52555316 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.43 5.95 0.31 6.48e-9 Electroencephalogram traits; LIHC cis rs2153535 0.580 rs1335643 chr6:8488021 T/G cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs1461503 0.934 rs7121840 chr11:122845360 A/G cg14473756 chr11:122847823 NA -0.35 -6.21 -0.32 1.56e-9 Menarche (age at onset); LIHC cis rs6089829 0.925 rs13041507 chr20:61666180 T/C cg03213289 chr20:61660250 NA 0.5 8.86 0.43 4.58e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 10.54 0.5 1.13e-22 Platelet count; LIHC trans rs2749592 0.550 rs4934881 chr10:37914346 A/C cg17830980 chr10:43048298 ZNF37B 0.41 7.7 0.38 1.47e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7223966 1.000 rs61360320 chr17:61800392 C/T cg05941027 chr17:61774174 LIMD2 0.36 7.54 0.38 4.22e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs116095464 0.558 rs13356367 chr5:242395 C/T cg22857025 chr5:266934 NA -1.48 -18.17 -0.7 4.09e-52 Breast cancer; LIHC cis rs2574704 0.851 rs2574718 chr3:11660689 A/T cg15876825 chr3:11651881 VGLL4 0.49 7.91 0.39 3.62e-14 Body mass index; LIHC cis rs7615952 0.599 rs66532274 chr3:125731845 G/A cg05084668 chr3:125655381 ALG1L -0.44 -7.22 -0.36 3.29e-12 Blood pressure (smoking interaction); LIHC cis rs8062405 1.000 rs4451951 chr16:28836205 T/C cg16576597 chr16:28551801 NUPR1 0.37 6.03 0.31 4.25e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs826838 0.904 rs7973992 chr12:39168233 T/C cg13010199 chr12:38710504 ALG10B 0.51 6.22 0.32 1.42e-9 Heart rate; LIHC cis rs611744 0.967 rs630492 chr8:109215368 C/T cg18478394 chr8:109455254 TTC35 -0.39 -6.93 -0.35 2.08e-11 Dupuytren's disease; LIHC cis rs921968 0.510 rs2577761 chr2:219462500 G/A cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.37e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs1568889 0.938 rs6484358 chr11:28260364 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.18 0.36 4.45e-12 Bipolar disorder; LIHC trans rs1814175 0.645 rs11040699 chr11:50023798 C/G cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs2933343 0.649 rs728839 chr3:128589359 A/G cg24203234 chr3:128598194 ACAD9 0.44 6.13 0.31 2.42e-9 IgG glycosylation; LIHC cis rs79149102 0.579 rs8039433 chr15:75367367 T/C cg09165964 chr15:75287851 SCAMP5 -0.56 -7.31 -0.37 1.95e-12 Lung cancer; LIHC trans rs2395128 0.834 rs7092435 chr10:76670311 C/G cg24341800 chr11:107992076 ACAT1 0.5 6.28 0.32 1.05e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs6450176 0.633 rs10054623 chr5:53343821 A/G ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.2 -0.58 1.94e-32 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs919433 0.617 rs4850809 chr2:198583403 C/T cg03934865 chr2:198174659 NA -0.48 -7.02 -0.35 1.22e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs593982 1.000 rs1941746 chr11:65502413 A/G cg08755490 chr11:65554678 OVOL1 0.55 8.56 0.42 3.82e-16 Atopic dermatitis; LIHC cis rs4629710 0.592 rs13206776 chr6:131576679 T/G cg12606694 chr6:131520996 AKAP7 0.63 7.26 0.37 2.65e-12 Multiple myeloma (IgH translocation); LIHC cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg03806693 chr22:41940476 POLR3H -1.08 -11.42 -0.53 8.04e-26 Crohn's disease;Inflammatory bowel disease; LIHC cis rs11190604 1.000 rs10883510 chr10:102297018 C/T cg07080220 chr10:102295463 HIF1AN 0.54 7.62 0.38 2.5e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs523522 0.962 rs2235218 chr12:120888619 A/C cg12219531 chr12:120966889 COQ5 0.64 12.26 0.55 6.92e-29 High light scatter reticulocyte count; LIHC cis rs7107174 1.000 rs72931690 chr11:78073192 G/A cg02023728 chr11:77925099 USP35 0.46 8.81 0.43 6.43e-17 Testicular germ cell tumor; LIHC trans rs3749237 0.964 rs62260719 chr3:49852419 G/A cg21659725 chr3:3221576 CRBN 0.76 11.21 0.52 4.67e-25 Resting heart rate; LIHC cis rs11122272 0.735 rs2474625 chr1:231519331 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs1008375 0.966 rs7675735 chr4:17587137 T/A cg16339924 chr4:17578868 LAP3 0.45 6.24 0.32 1.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.53 -7.52 -0.38 4.84e-13 Lymphocyte counts; LIHC cis rs36051895 0.589 rs7869015 chr9:5199750 C/T cg02405213 chr9:5042618 JAK2 -0.64 -10.67 -0.5 3.79e-23 Pediatric autoimmune diseases; LIHC cis rs9457247 1.000 rs416131 chr6:167406544 A/C cg23791538 chr6:167370224 RNASET2 0.61 10.22 0.48 1.4e-21 Crohn's disease; LIHC cis rs11628318 0.614 rs3825565 chr14:103060465 G/A cg23461800 chr14:103021989 NA -0.43 -6.05 -0.31 3.77e-9 Platelet count; LIHC cis rs11098499 0.604 rs12642411 chr4:120580525 T/C cg09307838 chr4:120376055 NA 0.67 9.78 0.47 4.46e-20 Corneal astigmatism; LIHC cis rs7312933 1.000 rs3229 chr12:42475888 G/A cg01256987 chr12:42539512 GXYLT1 -0.41 -6.86 -0.35 3.29e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs16912285 0.688 rs12276587 chr11:24280656 C/G ch.11.24196551F chr11:24239977 NA -0.77 -10.85 -0.51 8.96e-24 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs1144333 0.655 rs12405994 chr1:76435420 A/T cg10523679 chr1:76189770 ACADM 0.45 6.13 0.31 2.48e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs9372253 1.000 rs11153232 chr6:110716252 G/T cg00083206 chr6:110721305 DDO 0.31 6.34 0.32 7.39e-10 Platelet distribution width; LIHC cis rs10744422 1.000 rs10744422 chr12:123336789 T/C cg22842854 chr12:123319900 HIP1R -0.75 -9.92 -0.47 1.46e-20 Schizophrenia; LIHC cis rs35160687 0.644 rs11127024 chr2:86505453 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.36 5.88 0.3 9.52e-9 Night sleep phenotypes; LIHC cis rs11190604 0.767 rs10736150 chr10:102195341 G/A cg07080220 chr10:102295463 HIF1AN -0.48 -7.03 -0.36 1.14e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2629540 0.580 rs2930796 chr10:126485684 A/G cg08799069 chr10:126477246 METTL10 0.44 6.28 0.32 1.05e-9 Cocaine dependence; LIHC cis rs1801251 0.929 rs12694917 chr2:233707611 C/T cg25237894 chr2:233734115 C2orf82 -0.58 -11.44 -0.53 7.3e-26 Coronary artery disease; LIHC cis rs546131 0.642 rs12808574 chr11:34852120 A/C cg11058730 chr11:34937778 PDHX;APIP 0.51 6.42 0.33 4.47e-10 Lung disease severity in cystic fibrosis; LIHC cis rs9303401 0.659 rs34382037 chr17:56643550 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs7224737 1.000 rs12603327 chr17:40290552 T/C cg00647820 chr17:40259828 DHX58 -0.28 -5.91 -0.3 8.35e-9 Fibrinogen levels; LIHC cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg05368731 chr17:41323189 NBR1 0.69 11.34 0.52 1.68e-25 Menopause (age at onset); LIHC cis rs864537 0.590 rs1214596 chr1:167427170 A/T cg22356347 chr1:167427500 CD247 0.42 6.96 0.35 1.7e-11 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg08888203 chr3:10149979 C3orf24 0.57 6.49 0.33 3.06e-10 Alzheimer's disease; LIHC cis rs9640161 0.789 rs28432021 chr7:150046235 G/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.45 -7.36 -0.37 1.34e-12 Blood protein levels;Circulating chemerin levels; LIHC cis rs250677 0.687 rs36043 chr5:148440983 G/A cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg18306943 chr3:40428807 ENTPD3 0.35 6.09 0.31 3.1e-9 Renal cell carcinoma; LIHC cis rs9911578 0.835 rs1476596 chr17:56485358 C/T cg05425664 chr17:57184151 TRIM37 -0.57 -8.3 -0.41 2.46e-15 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs7275870 chr21:46671214 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.33 0.52 1.82e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs13063635 0.915 rs41289616 chr3:45997263 T/C cg21656520 chr2:210867290 RPE 0.85 6.08 0.31 3.19e-9 Eosinophil percentage of granulocytes; LIHC cis rs311392 0.526 rs167474 chr8:55101321 A/C cg11783602 chr8:55087084 NA -0.31 -6.23 -0.32 1.37e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs1023500 0.507 rs6002600 chr22:42488906 G/A cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Schizophrenia; LIHC cis rs9640161 0.750 rs1983440 chr7:150023941 G/C cg17279839 chr7:150038598 RARRES2 0.51 10.71 0.5 2.84e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg11494091 chr17:61959527 GH2 0.44 7.99 0.4 2.07e-14 Prudent dietary pattern; LIHC cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg18402987 chr7:1209562 NA 0.86 6.31 0.32 8.54e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12586317 0.547 rs112138868 chr14:35444385 C/T cg05294307 chr14:35346193 BAZ1A -0.47 -6.93 -0.35 2.15e-11 Psoriasis; LIHC cis rs12295403 1.000 rs12295403 chr11:18689653 G/T cg09887367 chr11:18690185 NA -0.41 -7.02 -0.35 1.21e-11 Ovarian reserve; LIHC cis rs7572733 0.534 rs4850815 chr2:198786167 G/T cg10820045 chr2:198174542 NA -0.47 -7.19 -0.36 4.07e-12 Dermatomyositis; LIHC cis rs875971 0.862 rs778707 chr7:65857027 G/A cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC cis rs2070488 0.775 rs2070489 chr3:38519424 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.76 12.57 0.56 4.66e-30 Electrocardiographic conduction measures; LIHC cis rs4665809 1.000 rs17040322 chr2:26351274 G/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs17685 0.753 rs10476 chr7:75696420 C/T cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.19 0.32 1.75e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs7618501 1.000 rs7634902 chr3:49762662 G/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC cis rs734999 0.505 rs4445406 chr1:2539400 T/C cg20673091 chr1:2541236 MMEL1 0.28 6.05 0.31 3.89e-9 Ulcerative colitis; LIHC cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.66 0.38 1.96e-13 Electroencephalogram traits; LIHC cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg16606324 chr3:10149918 C3orf24 0.55 5.85 0.3 1.17e-8 Alzheimer's disease; LIHC cis rs35110281 0.720 rs162393 chr21:44942692 G/A cg21573476 chr21:45109991 RRP1B -0.57 -10.56 -0.5 9.69e-23 Mean corpuscular volume; LIHC cis rs506338 0.517 rs490192 chr11:64471369 C/T cg21996761 chr11:64428434 NRXN2 0.35 5.81 0.3 1.39e-8 Body mass index;Urate levels; LIHC cis rs3741404 0.825 rs60452247 chr11:63981507 G/A cg18225595 chr11:63971243 STIP1 0.69 10.99 0.51 2.91e-24 Platelet count; LIHC cis rs8081395 0.932 rs2777885 chr17:57830473 C/A cg02344993 chr17:57696989 CLTC -0.45 -7.28 -0.37 2.28e-12 White blood cell count; LIHC cis rs899997 0.862 rs8043123 chr15:78973393 C/T cg04896959 chr15:78267971 NA -0.32 -6.02 -0.31 4.49e-9 Coronary artery disease or large artery stroke; LIHC cis rs2303759 0.830 rs7257053 chr19:49894456 C/G cg22590775 chr19:49891494 CCDC155 0.48 7.84 0.39 5.97e-14 Multiple sclerosis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22951283 chr11:67797908 NDUFS8 0.45 6.47 0.33 3.33e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1443512 0.704 rs4759308 chr12:54329031 A/T cg17410650 chr12:54324560 NA -0.4 -7.3 -0.37 1.98e-12 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs7903847 0.620 rs61863815 chr10:99124389 A/G cg06359132 chr10:99160096 RRP12 -0.4 -6.04 -0.31 4.02e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16780568 chr10:89578019 ATAD1;CFLP1 -0.44 -6.39 -0.33 5.35e-10 Pancreatic cancer; LIHC cis rs7520050 0.966 rs946529 chr1:46485548 G/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.82 0.3 1.38e-8 Red blood cell count;Reticulocyte count; LIHC cis rs713477 0.967 rs6573031 chr14:55913763 C/G cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.45e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg11301795 chr4:187892539 NA -0.26 -6.92 -0.35 2.22e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7666738 0.830 rs13147195 chr4:98893334 G/T cg05340658 chr4:99064831 C4orf37 0.66 11.9 0.54 1.49e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs9359856 0.529 rs72915915 chr6:90430593 T/C cg13799429 chr6:90582589 CASP8AP2 -0.66 -6.33 -0.32 7.6e-10 Bipolar disorder; LIHC cis rs10197940 0.578 rs6718372 chr2:152345871 C/G cg06191203 chr2:152266755 RIF1 -0.41 -7.15 -0.36 5.38e-12 Lung cancer; LIHC cis rs7639513 0.545 rs55977822 chr3:12704438 C/A cg23032965 chr3:12705835 RAF1 0.56 6.23 0.32 1.36e-9 Itch intensity from mosquito bite; LIHC cis rs2066819 1.000 rs11171806 chr12:56733531 A/G cg26734620 chr12:56694298 CS -1.25 -11.04 -0.51 1.96e-24 Psoriasis vulgaris; LIHC cis rs734999 0.588 rs2764842 chr1:2529192 A/G cg18854424 chr1:2615690 NA -0.33 -7.25 -0.36 2.83e-12 Ulcerative colitis; LIHC trans rs1005277 0.579 rs1780146 chr10:38517874 C/A cg27523141 chr10:43048294 ZNF37B 0.38 6.42 0.33 4.69e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6430585 0.583 rs111837148 chr2:136612036 G/A cg15123519 chr2:136567270 LCT -0.37 -5.87 -0.3 1.01e-8 Corneal structure; LIHC cis rs11025559 0.773 rs10833334 chr11:20498640 T/C cg19653624 chr11:20408972 PRMT3 -0.51 -6.52 -0.33 2.59e-10 Pursuit maintenance gain; LIHC cis rs9291683 0.609 rs3796836 chr4:10011345 A/G cg11266682 chr4:10021025 SLC2A9 0.32 6.76 0.34 5.95e-11 Bone mineral density; LIHC cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg11301795 chr4:187892539 NA 0.27 7.31 0.37 1.95e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg10755058 chr3:40428713 ENTPD3 0.4 6.9 0.35 2.58e-11 Renal cell carcinoma; LIHC cis rs10504073 0.584 rs62507178 chr8:49938572 A/C cg00325661 chr8:49890786 NA 0.36 7.97 0.4 2.31e-14 Blood metabolite ratios; LIHC trans rs867371 1.000 rs1392976 chr15:82446175 A/G cg18393722 chr15:85113863 UBE2QP1 0.4 6.89 0.35 2.72e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs9814567 0.929 rs1534027 chr3:134284662 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.66 -12.05 -0.55 4.02e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3768617 0.811 rs61808068 chr1:182979377 T/A ch.1.3577855R chr1:183094577 LAMC1 0.48 7.55 0.38 4.03e-13 Fuchs's corneal dystrophy; LIHC cis rs72781680 0.898 rs6712524 chr2:24083925 T/C cg08917208 chr2:24149416 ATAD2B 0.86 8.17 0.4 5.99e-15 Lymphocyte counts; LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg00106254 chr7:1943704 MAD1L1 -0.44 -7.31 -0.37 1.89e-12 Bipolar disorder and schizophrenia; LIHC cis rs10771431 0.817 rs17202253 chr12:9361850 A/G cg08997352 chr12:9597637 DDX12 -0.54 -8.45 -0.42 8.72e-16 Breast size; LIHC cis rs4819052 0.684 rs914216 chr21:46698298 T/G cg22633049 chr21:46681294 NA -0.38 -6.47 -0.33 3.38e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs143111788 1 rs143111788 chr6:41919175 CCAGCTACT/C cg17623882 chr6:41773611 USP49 -0.5 -7.4 -0.37 1.09e-12 Red cell distribution width; LIHC cis rs16858210 0.826 rs35494670 chr3:183606357 T/G cg25686905 chr3:183603175 PARL -0.49 -9.29 -0.45 1.78e-18 Menopause (age at onset); LIHC cis rs919433 0.680 rs11680291 chr2:198409884 A/G cg03934865 chr2:198174659 NA 0.51 7.82 0.39 6.8e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2404602 0.967 rs7174096 chr15:77072400 A/G cg23625390 chr15:77176239 SCAPER 0.41 6.95 0.35 1.86e-11 Blood metabolite levels; LIHC cis rs5769707 0.521 rs9616715 chr22:50058582 C/T cg07959070 chr22:50026188 C22orf34 -0.3 -7.22 -0.36 3.33e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6754311 0.593 rs10186843 chr2:136586958 C/A cg07169764 chr2:136633963 MCM6 -0.68 -10.2 -0.48 1.66e-21 Mosquito bite size; LIHC cis rs2180341 0.781 rs7742161 chr6:127571676 T/C cg27446573 chr6:127587934 RNF146 0.66 10.03 0.48 6.25e-21 Breast cancer; LIHC cis rs875971 0.545 rs4718335 chr7:65804606 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.24 0.36 3.03e-12 Aortic root size; LIHC cis rs9596863 1.000 rs9568948 chr13:54437693 A/C ch.13.53330881F chr13:54432880 NA 0.43 5.91 0.3 8.34e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1348850 0.645 rs4893963 chr2:178430747 A/G cg27490568 chr2:178487706 NA -0.76 -9.64 -0.46 1.27e-19 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs12753920 0.724 rs7541482 chr1:92566853 G/C cg15668468 chr10:118892869 VAX1 0.43 6.11 0.31 2.75e-9 Systemic lupus erythematosus; LIHC cis rs1355223 0.583 rs2915178 chr11:34878051 C/T cg11058730 chr11:34937778 PDHX;APIP 0.77 14.0 0.6 1.63e-35 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs45544231 0.544 rs8052175 chr16:52577142 C/T cg09051775 chr16:52580266 TOX3 -0.32 -5.89 -0.3 9.47e-9 Restless legs syndrome; LIHC cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.54 0.46 2.76e-19 Bipolar disorder; LIHC cis rs1892700 0.764 rs62227660 chr21:34891096 G/A cg14850771 chr21:34775459 IFNGR2 -0.45 -5.93 -0.31 7.59e-9 Educational attainment; LIHC cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.53 -7.68 -0.38 1.64e-13 Prostate cancer; LIHC cis rs1801251 0.644 rs283473 chr2:233654847 A/G cg25237894 chr2:233734115 C2orf82 0.4 7.68 0.38 1.65e-13 Coronary artery disease; LIHC cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg07061783 chr6:25882402 NA 0.67 8.97 0.44 1.99e-17 Blood metabolite levels; LIHC cis rs6545883 0.929 rs2593626 chr2:61665184 C/A cg14146966 chr2:61757674 XPO1 0.45 7.69 0.38 1.61e-13 Tuberculosis; LIHC cis rs11690935 0.959 rs973889 chr2:172579954 A/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.71 -0.69 2.99e-50 Schizophrenia; LIHC cis rs9506514 0.509 rs9509294 chr13:21174645 T/A cg27234864 chr13:21295941 IL17D -0.33 -5.89 -0.3 9.45e-9 Coronary artery calcification; LIHC cis rs950169 0.526 rs698620 chr15:85177208 G/A cg11189052 chr15:85197271 WDR73 -0.49 -7.63 -0.38 2.37e-13 Schizophrenia; LIHC cis rs11711311 1.000 rs2712348 chr3:113460614 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.42 -0.37 9.42e-13 IgG glycosylation; LIHC cis rs11758351 0.866 rs56186759 chr6:26207181 C/T cg11342453 chr6:26196699 NA 0.52 5.8 0.3 1.55e-8 Gout;Renal underexcretion gout; LIHC cis rs2559856 0.935 rs7957666 chr12:102081551 T/C cg12924262 chr12:102091054 CHPT1 0.5 7.95 0.4 2.7e-14 Blood protein levels; LIHC cis rs870825 0.860 rs60523653 chr4:185604676 T/C cg04058563 chr4:185651563 MLF1IP 0.76 6.49 0.33 3.05e-10 Blood protein levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07837717 chr19:2841006 ZNF555 -0.42 -6.32 -0.32 8.27e-10 Cognitive function; LIHC cis rs10193935 0.901 rs10490552 chr2:42559947 C/T cg27598129 chr2:42591480 NA 0.73 11.69 0.53 8.59e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7119 0.717 rs35268067 chr15:77753688 C/G cg17802220 chr15:77601643 NA -0.4 -6.84 -0.35 3.65e-11 Type 2 diabetes; LIHC cis rs1005277 0.579 rs2472178 chr10:38384750 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.39 -5.77 -0.3 1.81e-8 Extrinsic epigenetic age acceleration; LIHC cis rs881375 0.900 rs1008383 chr9:123683579 C/G cg14580859 chr9:123691850 NA 0.38 6.69 0.34 9.15e-11 Rheumatoid arthritis; LIHC cis rs6912958 0.781 rs4707376 chr6:88270947 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.43 -7.58 -0.38 3.38e-13 Monocyte percentage of white cells; LIHC cis rs7223966 1.000 rs6504173 chr17:61735056 T/C cg05941027 chr17:61774174 LIMD2 0.29 5.82 0.3 1.39e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs600806 0.888 rs680434 chr1:109842271 C/T cg23091122 chr1:110024289 SYPL2 -0.46 -5.82 -0.3 1.37e-8 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg00684032 chr4:1343700 KIAA1530 -0.5 -7.27 -0.37 2.47e-12 Obesity-related traits; LIHC cis rs4853012 0.838 rs2177707 chr2:74356850 A/G cg05890377 chr2:74357713 NA 0.63 12.52 0.56 7.21e-30 Gestational age at birth (maternal effect); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21113846 chr7:837536 NA -0.46 -6.51 -0.33 2.69e-10 Lung function (FEV1/FVC); LIHC cis rs6762 0.692 rs7928925 chr11:839155 G/A cg15787769 chr11:842744 TSPAN4;POLR2L -0.61 -7.32 -0.37 1.77e-12 Mean platelet volume; LIHC cis rs11098499 0.954 rs66506550 chr4:120371445 T/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs4843747 0.519 rs12599755 chr16:88107006 A/G cg07560587 chr16:88016574 BANP 0.36 5.8 0.3 1.48e-8 Menopause (age at onset); LIHC cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg25072359 chr17:41440525 NA 0.39 6.19 0.32 1.77e-9 Menopause (age at onset); LIHC cis rs3204270 0.639 rs7216239 chr17:79660187 C/T cg18367735 chr17:79674897 NA 0.7 8.2 0.41 4.81e-15 Dental caries; LIHC cis rs12477438 0.520 rs2309581 chr2:99784292 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.9 -12.77 -0.57 8.49e-31 Chronic sinus infection; LIHC cis rs7512552 0.803 rs2454286 chr1:150355538 G/A cg15654264 chr1:150340011 RPRD2 0.68 11.14 0.52 8.17e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9296092 0.538 rs62405941 chr6:33517297 G/A cg13560919 chr6:33536144 NA -0.37 -6.05 -0.31 3.9e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7911264 0.628 rs6583833 chr10:94409800 C/T cg25506282 chr10:94462361 NA 0.37 6.25 0.32 1.19e-9 Inflammatory bowel disease; LIHC cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg05697976 chr12:29376483 FAR2 0.34 7.08 0.36 8.25e-12 QT interval; LIHC cis rs2243480 1.000 rs73142122 chr7:65311298 C/A cg07424592 chr7:64974309 NA 0.81 9.05 0.44 1.13e-17 Diabetic kidney disease; LIHC cis rs7264396 0.528 rs7273880 chr20:34551507 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs950169 0.840 rs62029595 chr15:84955301 C/T cg17507749 chr15:85114479 UBE2QP1 0.73 8.48 0.42 6.83e-16 Schizophrenia; LIHC cis rs4919694 1.000 rs4919694 chr10:104698978 T/C cg04362960 chr10:104952993 NT5C2 0.76 7.82 0.39 6.6e-14 Arsenic metabolism; LIHC cis rs13161895 0.818 rs116463976 chr5:179484519 G/C cg02702477 chr5:179499311 RNF130 0.9 11.93 0.54 1.11e-27 LDL cholesterol; LIHC cis rs28374715 0.532 rs11854632 chr15:41682094 A/G cg18705301 chr15:41695430 NDUFAF1 1.2 18.27 0.7 1.57e-52 Ulcerative colitis; LIHC cis rs9733 0.818 rs11204695 chr1:150657011 T/G cg18016565 chr1:150552671 MCL1 -0.5 -10.34 -0.49 5.31e-22 Tonsillectomy; LIHC cis rs155076 0.711 rs4770131 chr13:21897468 A/G cg11317459 chr13:21872234 NA 0.99 10.53 0.49 1.22e-22 White matter hyperintensity burden; LIHC cis rs6545883 0.929 rs7563678 chr2:61741811 C/T cg14146966 chr2:61757674 XPO1 -0.48 -8.45 -0.42 8.2e-16 Tuberculosis; LIHC cis rs6426558 0.537 rs488104 chr1:227300277 G/A cg10327440 chr1:227177885 CDC42BPA 0.46 7.15 0.36 5.37e-12 Neutrophil percentage of white cells; LIHC cis rs2576037 0.526 rs2571024 chr18:44557877 G/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.47 6.76 0.34 5.88e-11 Personality dimensions; LIHC cis rs11671005 0.695 rs8106061 chr19:58917990 G/A cg25952890 chr19:58913133 NA 0.69 7.43 0.37 8.91e-13 Mean platelet volume; LIHC cis rs7116495 0.786 rs1573501 chr11:71735693 C/T cg26138937 chr11:71823887 C11orf51 -1.31 -10.43 -0.49 2.7e-22 Severe influenza A (H1N1) infection; LIHC cis rs701145 0.556 rs355758 chr3:154007682 C/G cg16511985 chr3:153974050 SGEF -0.41 -8.79 -0.43 7.42e-17 Coronary artery disease; LIHC cis rs250677 0.687 rs1422581 chr5:148437386 C/T cg12140854 chr5:148520817 ABLIM3 0.44 5.98 0.31 5.64e-9 Breast cancer; LIHC cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg13397359 chr6:42928475 GNMT 0.65 9.45 0.46 5.5e-19 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs2243480 1.000 rs316321 chr7:65611613 G/A cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs559928 0.606 rs11600628 chr11:63976027 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 8.11 0.4 9.47e-15 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs9393692 0.905 rs9393693 chr6:26277408 C/A cg00631329 chr6:26305371 NA -0.43 -7.25 -0.36 2.88e-12 Educational attainment; LIHC cis rs7894407 0.504 rs7089271 chr10:105176914 A/G cg05636881 chr10:105038444 INA 0.42 6.68 0.34 9.85e-11 White matter hyperintensity burden; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.81 0.76 1.06e-66 Height; LIHC cis rs2279817 0.863 rs6586569 chr1:18027377 T/C cg21791023 chr1:18019539 ARHGEF10L 0.42 6.3 0.32 9.12e-10 Neuroticism; LIHC cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg05368731 chr17:41323189 NBR1 0.73 12.51 0.56 7.88e-30 Menopause (age at onset); LIHC cis rs3796352 1.000 rs11720191 chr3:53013839 T/C cg07884673 chr3:53033167 SFMBT1 0.91 6.6 0.34 1.58e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs798554 0.671 rs1182195 chr7:2868730 A/G cg19717773 chr7:2847554 GNA12 -0.44 -7.31 -0.37 1.86e-12 Height; LIHC cis rs74233809 1.000 rs11191531 chr10:104806898 G/C cg03493300 chr10:104813866 CNNM2 0.47 6.26 0.32 1.16e-9 Birth weight; LIHC cis rs7715806 0.500 rs17649362 chr5:75008958 C/T cg19683494 chr5:74908142 NA 0.68 7.85 0.39 5.41e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2257205 0.667 rs8070407 chr17:56709172 G/A cg12560992 chr17:57184187 TRIM37 0.69 7.62 0.38 2.44e-13 Pancreatic cancer; LIHC cis rs6088590 1.000 rs6120748 chr20:33458284 T/G cg24642439 chr20:33292090 TP53INP2 0.76 10.07 0.48 4.72e-21 Coronary artery disease; LIHC cis rs12477438 0.798 rs6761570 chr2:99577276 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.06 -0.51 1.7e-24 Chronic sinus infection; LIHC trans rs4714291 0.832 rs1923462 chr6:39976100 T/C cg02267698 chr19:7991119 CTXN1 -0.39 -6.43 -0.33 4.42e-10 Strep throat; LIHC cis rs2279817 0.780 rs3766312 chr1:17978644 G/C cg21791023 chr1:18019539 ARHGEF10L -0.66 -7.2 -0.36 3.8e-12 Neuroticism; LIHC cis rs7918232 0.941 rs4749230 chr10:27441218 C/T cg14240646 chr10:27532245 ACBD5 -0.63 -5.96 -0.31 6.27e-9 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19140410 chr17:78518857 RPTOR 0.49 6.73 0.34 7.22e-11 Lung function (FEV1/FVC); LIHC cis rs765787 0.530 rs16941017 chr15:45543281 T/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.75 -0.3 2.03e-8 Uric acid levels; LIHC cis rs2012796 0.872 rs59397507 chr14:81821334 A/G cg02996355 chr14:81879375 NA 0.45 6.79 0.34 5.04e-11 Night sleep phenotypes; LIHC cis rs8072100 1.000 rs4375701 chr17:45712218 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.4 -6.35 -0.32 7e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2479724 0.805 rs11756454 chr6:41798578 T/A cg17623882 chr6:41773611 USP49 0.56 8.47 0.42 7.31e-16 Menarche (age at onset); LIHC cis rs9828933 0.752 rs13434089 chr3:63948566 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.75 9.59 0.46 1.95e-19 Type 2 diabetes; LIHC trans rs9217 0.513 rs7216801 chr17:7386811 A/T cg08566640 chr11:64091735 NA -0.67 -6.13 -0.31 2.36e-9 Height; LIHC cis rs11166927 0.548 rs28366721 chr8:140827797 C/G cg16909799 chr8:140841666 TRAPPC9 -0.44 -7.04 -0.36 1.04e-11 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs1023500 0.551 rs2859438 chr22:42466980 A/T cg05082376 chr22:42548792 NA -0.39 -5.79 -0.3 1.63e-8 Schizophrenia; LIHC cis rs2153535 0.580 rs7341383 chr6:8470634 A/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs34779708 0.931 rs34876468 chr10:35424450 G/A cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17756712 0.607 rs1747599 chr6:633557 C/A cg14374089 chr6:596013 EXOC2 0.4 5.71 0.3 2.42e-8 Vertical cup-disc ratio; LIHC cis rs1878931 0.543 rs17612463 chr16:3420479 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.68 9.0 0.44 1.63e-17 Body mass index (adult); LIHC cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.8 7.86 0.39 5.07e-14 Platelet count; LIHC cis rs9378688 1.000 rs9378687 chr6:2218835 A/G cg12303981 chr6:2244766 GMDS -0.5 -6.34 -0.32 7.23e-10 Caudate nucleus volume; LIHC cis rs28374715 0.532 rs28477406 chr15:41642036 C/G cg18705301 chr15:41695430 NDUFAF1 -1.27 -18.69 -0.71 3.23e-54 Ulcerative colitis; LIHC cis rs12530845 0.673 rs4073627 chr7:135312572 A/G cg23117316 chr7:135346802 PL-5283 0.41 6.34 0.32 7.22e-10 Red blood cell traits; LIHC cis rs28595532 0.545 rs13144171 chr4:119257458 G/A cg21605333 chr4:119757512 SEC24D 0.79 6.65 0.34 1.19e-10 Cannabis dependence symptom count; LIHC cis rs2976388 0.506 rs2572902 chr8:143791387 A/G cg06565975 chr8:143823917 SLURP1 0.33 6.33 0.32 7.51e-10 Urinary tract infection frequency; LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg14893161 chr1:205819251 PM20D1 0.6 8.75 0.43 9.75e-17 Menarche (age at onset); LIHC cis rs7927592 0.913 rs2236708 chr11:68378045 G/A cg01657329 chr11:68192670 LRP5 -0.48 -6.21 -0.32 1.57e-9 Total body bone mineral density; LIHC cis rs6964587 0.692 rs6953256 chr7:91575417 C/T cg17063962 chr7:91808500 NA -0.64 -11.26 -0.52 3.18e-25 Breast cancer; LIHC cis rs1538970 0.924 rs1826691 chr1:45881262 A/G cg24296786 chr1:45957014 TESK2 0.5 7.01 0.35 1.25e-11 Platelet count; LIHC cis rs60871478 0.947 rs62432239 chr7:794576 C/T cg13844804 chr7:814759 HEATR2 0.43 5.87 0.3 1.04e-8 Cerebrospinal P-tau181p levels; LIHC cis rs9534288 0.912 rs2404732 chr13:46618611 C/A cg15192986 chr13:46630673 CPB2 -0.58 -8.61 -0.42 2.66e-16 Blood protein levels; LIHC trans rs783540 0.500 rs7178459 chr15:83398384 T/C cg18393722 chr15:85113863 UBE2QP1 0.46 6.53 0.33 2.39e-10 Schizophrenia; LIHC cis rs2806561 0.704 rs6680974 chr1:23376233 A/G cg12483005 chr1:23474871 LUZP1 0.46 6.94 0.35 1.92e-11 Height; LIHC cis rs4803468 1.000 rs8105833 chr19:41896145 G/A cg14132834 chr19:41945861 ATP5SL -0.4 -5.96 -0.31 6.44e-9 Height; LIHC cis rs1801251 1.000 rs35212961 chr2:233582762 C/T cg25237894 chr2:233734115 C2orf82 0.58 11.13 0.52 9.37e-25 Coronary artery disease; LIHC cis rs7223966 1.000 rs11870797 chr17:61804622 C/T cg05941027 chr17:61774174 LIMD2 0.36 7.54 0.38 4.22e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2607426 0.579 rs1869710 chr19:41256375 C/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.53 -5.85 -0.3 1.12e-8 Blood protein levels; LIHC cis rs4819052 1.000 rs2297286 chr21:46707897 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.76 10.41 0.49 3.05e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5758511 0.680 rs17002902 chr22:42625509 C/G cg20195005 chr22:42527684 CYP2D6 0.3 5.76 0.3 1.85e-8 Birth weight; LIHC cis rs2075165 0.901 rs1043165 chr1:156220056 T/C cg07234388 chr1:156261841 TMEM79 0.51 8.85 0.43 4.8e-17 Tonsillectomy; LIHC cis rs13161895 0.818 rs114211674 chr5:179484518 A/C cg06664874 chr5:179499304 RNF130 0.67 7.7 0.38 1.51e-13 LDL cholesterol; LIHC cis rs7395581 0.918 rs4752825 chr11:47352409 G/A cg25783544 chr11:47291846 MADD 0.41 5.95 0.31 6.76e-9 HDL cholesterol; LIHC cis rs6446731 0.517 rs2071668 chr4:3269905 A/G cg06533319 chr4:3265114 C4orf44 0.31 5.75 0.3 1.99e-8 Mean platelet volume; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg16927353 chr2:10442868 HPCAL1 -0.43 -6.17 -0.32 1.92e-9 Neuroblastoma; LIHC cis rs6912958 0.559 rs242267 chr6:88061837 A/G cg04972856 chr6:88032051 C6orf162;GJB7 -0.32 -5.8 -0.3 1.5e-8 Monocyte percentage of white cells; LIHC cis rs950169 0.922 rs11638445 chr15:85137694 C/A cg17507749 chr15:85114479 UBE2QP1 0.74 8.14 0.4 7.28e-15 Schizophrenia; LIHC cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg18402987 chr7:1209562 NA 0.76 6.04 0.31 4.04e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2976388 1.000 rs2978982 chr8:143763490 T/C cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs763121 0.853 rs138702 chr22:39132601 A/T cg14440974 chr22:39074834 NA 0.35 5.91 0.3 8.08e-9 Menopause (age at onset); LIHC trans rs208520 0.955 rs208538 chr6:66964492 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.68 -0.34 9.52e-11 Exhaled nitric oxide output; LIHC cis rs3790844 0.613 rs12030331 chr1:200001547 G/A cg07208853 chr1:200005219 NR5A2 0.38 8.29 0.41 2.59e-15 Pancreatic cancer; LIHC cis rs7772486 0.738 rs75288066 chr6:146319386 C/A cg23711669 chr6:146136114 FBXO30 0.63 10.31 0.49 7.02e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs1144333 0.655 rs12401729 chr1:76336586 T/G cg03433033 chr1:76189801 ACADM 0.54 7.44 0.37 8.34e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg03188948 chr7:1209495 NA 0.77 5.74 0.3 2.07e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs26868 0.690 rs26835 chr16:2237549 C/T cg25665528 chr16:2260870 C16orf79 -0.37 -6.61 -0.34 1.48e-10 Height; LIHC cis rs7224685 0.569 rs7215798 chr17:4007666 C/G cg09695851 chr17:3907499 NA -0.57 -7.01 -0.35 1.31e-11 Type 2 diabetes; LIHC cis rs950776 0.593 rs6495306 chr15:78865893 C/T cg06917634 chr15:78832804 PSMA4 -0.72 -9.65 -0.46 1.25e-19 Sudden cardiac arrest; LIHC cis rs7582180 0.652 rs12997725 chr2:100935136 A/G cg14675211 chr2:100938903 LONRF2 0.56 8.8 0.43 6.83e-17 Intelligence (multi-trait analysis); LIHC trans rs11088226 0.846 rs13047501 chr21:33924660 G/A cg09050820 chr6:167586206 TCP10L2 0.76 12.5 0.56 8.46e-30 Gastritis; LIHC cis rs11233413 1.000 rs11233413 chr11:82723072 T/C cg24227371 chr11:82718527 RAB30 -0.32 -7.07 -0.36 8.87e-12 Economic and political preferences (feminism/equality); LIHC cis rs2346177 0.844 rs13010062 chr2:46644137 C/G cg02822958 chr2:46747628 ATP6V1E2 0.41 6.31 0.32 8.7e-10 HDL cholesterol; LIHC cis rs5769765 0.862 rs9616385 chr22:50313124 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.1 11.94 0.54 1.07e-27 Platelet count; LIHC cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg08888203 chr3:10149979 C3orf24 0.54 6.55 0.33 2.09e-10 Alzheimer's disease; LIHC cis rs10751667 0.666 rs7934963 chr11:957220 C/T cg10932868 chr11:921992 NA 0.37 7.01 0.35 1.26e-11 Alzheimer's disease (late onset); LIHC cis rs9297145 0.509 rs13222381 chr7:98785024 T/G cg05967295 chr7:98741636 SMURF1 -0.39 -6.56 -0.33 1.99e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs11677370 0.603 rs10164826 chr2:3849951 G/C cg17052675 chr2:3827356 NA -0.53 -6.75 -0.34 6.37e-11 Type 2 diabetes; LIHC trans rs7937682 0.855 rs11213985 chr11:111581521 C/A cg18187862 chr3:45730750 SACM1L 0.56 6.67 0.34 1.03e-10 Primary sclerosing cholangitis; LIHC cis rs1707322 0.721 rs11211166 chr1:46157942 G/A cg06784218 chr1:46089804 CCDC17 0.42 7.74 0.39 1.11e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6450176 0.909 rs6884760 chr5:53293077 T/A ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.23 -0.64 2.38e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 10.0 0.48 8.05e-21 Mean platelet volume; LIHC cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10792665 0.573 rs7104980 chr11:82575195 C/G cg24227371 chr11:82718527 RAB30 -0.28 -6.61 -0.34 1.45e-10 Obesity-related traits; LIHC cis rs40363 0.645 rs6501177 chr16:3523681 C/T cg21433313 chr16:3507492 NAT15 0.47 7.9 0.39 3.86e-14 Tuberculosis; LIHC cis rs2839186 0.934 rs2839194 chr21:47699437 T/G cg12016809 chr21:47604291 C21orf56 0.41 5.97 0.31 6.06e-9 Testicular germ cell tumor; LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.58 -8.47 -0.42 7.57e-16 Lymphocyte counts; LIHC cis rs6121246 0.821 rs3181073 chr20:30307199 A/C cg13852791 chr20:30311386 BCL2L1 -0.97 -9.8 -0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs6061231 0.761 rs2427312 chr20:60970591 C/T cg09594475 chr20:60884601 LAMA5 0.58 6.21 0.32 1.51e-9 Colorectal cancer; LIHC cis rs8017423 0.967 rs11159958 chr14:90716051 T/C cg14092571 chr14:90743983 NA -0.38 -6.13 -0.31 2.46e-9 Mortality in heart failure; LIHC cis rs17685 0.753 rs10251863 chr7:75790192 T/C cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.57e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9818758 0.607 rs55873331 chr3:49597055 C/T cg00383909 chr3:49044727 WDR6 0.82 6.42 0.33 4.69e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs763121 0.853 rs5757193 chr22:39034867 A/G cg06022373 chr22:39101656 GTPBP1 -0.68 -11.34 -0.52 1.59e-25 Menopause (age at onset); LIHC cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg08132940 chr7:1081526 C7orf50 -0.77 -6.47 -0.33 3.47e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs892961 0.932 rs9916143 chr17:75409282 C/G cg01320579 chr17:75405842 SEPT9 -0.5 -7.28 -0.37 2.33e-12 Airflow obstruction; LIHC cis rs2439831 0.681 rs1549523 chr15:43624189 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.64 0.53 1.34e-26 Lung cancer in ever smokers; LIHC cis rs7772486 0.790 rs9403756 chr6:146257761 C/G cg23711669 chr6:146136114 FBXO30 -0.69 -11.68 -0.53 9.73e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs8067545 0.750 rs4925079 chr17:19986861 T/A cg13482628 chr17:19912719 NA 0.49 8.22 0.41 4.28e-15 Schizophrenia; LIHC cis rs798554 0.704 rs709282 chr7:2769921 G/A cg13628971 chr7:2884303 GNA12 0.4 6.32 0.32 8.35e-10 Height; LIHC cis rs7903847 0.642 rs6584128 chr10:99171926 G/T cg20016023 chr10:99160130 RRP12 0.43 7.06 0.36 9.41e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs10779751 0.770 rs11581010 chr1:11212458 A/G cg08854313 chr1:11322531 MTOR -0.75 -9.63 -0.46 1.45e-19 Body mass index; LIHC cis rs17685 0.753 rs1104879 chr7:75685568 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.3 -0.32 9.15e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg22561889 chr6:118971681 C6orf204 -0.55 -6.53 -0.33 2.39e-10 Diastolic blood pressure; LIHC cis rs6442522 0.615 rs13060973 chr3:15500933 A/G cg16303742 chr3:15540471 COLQ -0.44 -7.43 -0.37 9.01e-13 Uric acid levels; LIHC cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 9.3 0.45 1.69e-18 Platelet count; LIHC cis rs9814567 0.752 rs1880378 chr3:134330709 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7408868 1.000 rs4809029 chr19:15273248 A/C cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC cis rs16986825 0.607 rs5762852 chr22:29242473 T/C cg15103426 chr22:29168792 CCDC117 0.44 5.87 0.3 1e-8 Pancreatic cancer; LIHC cis rs35110281 0.776 rs62226866 chr21:45024186 T/C cg21573476 chr21:45109991 RRP1B -0.57 -10.71 -0.5 2.86e-23 Mean corpuscular volume; LIHC cis rs12477438 0.798 rs1453561 chr2:99613924 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.44 -0.64 3.61e-41 Chronic sinus infection; LIHC cis rs9649465 0.967 rs12534834 chr7:123307079 T/C cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.58e-14 Migraine; LIHC cis rs62179067 0.708 rs10497532 chr2:179935156 C/T cg20701897 chr2:179586761 TTN -0.48 -5.77 -0.3 1.82e-8 Late-onset Alzheimer's disease; LIHC cis rs62179067 0.708 rs11887988 chr2:179943041 G/A cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs9517320 0.534 rs4772090 chr13:99150674 T/C cg20487152 chr13:99095054 FARP1 -0.37 -6.21 -0.32 1.56e-9 Longevity; LIHC cis rs79149102 0.579 rs12592477 chr15:75292699 C/T cg17294928 chr15:75287854 SCAMP5 -0.53 -6.71 -0.34 8.12e-11 Lung cancer; LIHC cis rs17711722 0.727 rs781151 chr7:65479878 T/C cg14393609 chr7:65229607 NA 0.43 6.14 0.31 2.34e-9 Calcium levels; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.4 -0.33 5e-10 Total body bone mineral density; LIHC cis rs36051895 0.623 rs10118267 chr9:5243736 T/C cg02405213 chr9:5042618 JAK2 -0.65 -10.34 -0.49 5.29e-22 Pediatric autoimmune diseases; LIHC trans rs79243044 0.786 rs16932549 chr11:5560909 C/T cg18222961 chr2:48009935 MSH6 -0.49 -6.3 -0.32 9.23e-10 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs875971 0.619 rs12533585 chr7:65984605 G/C cg00343986 chr7:65444356 GUSB 0.4 5.99 0.31 5.42e-9 Aortic root size; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg14348182 chr9:138823525 NA 0.37 6.24 0.32 1.26e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs72843506 0.656 rs7210439 chr17:19986041 T/C cg12065943 chr17:19881925 AKAP10 -0.33 -5.76 -0.3 1.9e-8 Schizophrenia; LIHC trans rs7395662 0.553 rs4882155 chr11:48705801 T/C cg03929089 chr4:120376271 NA -0.44 -6.66 -0.34 1.12e-10 HDL cholesterol; LIHC cis rs875971 0.862 rs4236208 chr7:65749078 C/T cg11764359 chr7:65958608 NA -0.85 -15.31 -0.64 1.2e-40 Aortic root size; LIHC cis rs2836950 0.501 rs2056844 chr21:40670460 G/C cg11890956 chr21:40555474 PSMG1 -0.43 -6.86 -0.35 3.18e-11 Menarche (age at onset); LIHC cis rs35306767 0.714 rs67205460 chr10:1090366 C/T cg20503657 chr10:835505 NA 0.71 6.8 0.35 4.68e-11 Eosinophil percentage of granulocytes; LIHC cis rs7474896 0.537 rs2749586 chr10:38270214 G/C cg25427524 chr10:38739819 LOC399744 0.44 5.86 0.3 1.07e-8 Obesity (extreme); LIHC cis rs34779708 0.966 rs12773647 chr10:35440327 A/G cg03585969 chr10:35415529 CREM 0.85 12.93 0.57 2.16e-31 Inflammatory bowel disease;Crohn's disease; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg04400940 chr3:150329548 SELT 0.42 6.23 0.32 1.36e-9 Immature fraction of reticulocytes; LIHC cis rs12497850 0.931 rs12493289 chr3:48905161 G/A cg07636037 chr3:49044803 WDR6 0.93 16.86 0.67 7.27e-47 Parkinson's disease; LIHC cis rs807029 0.577 rs7902510 chr10:102757934 C/T cg17130504 chr10:102756923 LZTS2 0.55 7.56 0.38 3.84e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs8062405 1.000 rs9972693 chr16:28859802 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1816752 0.683 rs7330532 chr13:25017591 C/T cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.81e-10 Obesity-related traits; LIHC cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg09222892 chr1:25734099 RHCE 0.45 8.27 0.41 3e-15 Erythrocyte sedimentation rate; LIHC trans rs875971 0.545 rs1796226 chr7:66087710 C/T cg26939375 chr7:64535504 NA 0.39 6.21 0.32 1.52e-9 Aortic root size; LIHC cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.85 0.3 1.17e-8 Menopause (age at onset); LIHC cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg06481639 chr22:41940642 POLR3H 0.65 6.59 0.34 1.69e-10 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02891801 chr12:6472782 SCNN1A 0.44 6.28 0.32 1.06e-9 Pancreatic cancer; LIHC cis rs3008870 1.000 rs2755250 chr1:67495283 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.15 0.66 5.24e-44 Lymphocyte percentage of white cells; LIHC cis rs918629 0.530 rs11738768 chr5:95237780 C/A cg10483112 chr5:95245456 ELL2 -0.36 -6.55 -0.33 2.08e-10 IgG glycosylation; LIHC cis rs7772486 0.875 rs10872582 chr6:146373061 G/A cg05347473 chr6:146136440 FBXO30 0.35 5.85 0.3 1.13e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6121246 0.865 rs6089055 chr20:30324045 C/T cg13852791 chr20:30311386 BCL2L1 0.89 8.53 0.42 4.9e-16 Mean corpuscular hemoglobin; LIHC cis rs2073300 0.609 rs6137938 chr20:23389127 C/G cg16736954 chr20:23401023 NAPB 0.73 8.68 0.43 1.6e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8062405 1.000 rs8055982 chr16:28881202 A/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs919433 0.679 rs6757669 chr2:198530355 C/T cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs11098499 0.954 rs6820115 chr4:120398182 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.58 0.42 3.35e-16 Corneal astigmatism; LIHC cis rs6121246 0.865 rs77130187 chr20:30269060 G/A cg13852791 chr20:30311386 BCL2L1 0.85 7.26 0.37 2.55e-12 Mean corpuscular hemoglobin; LIHC cis rs921968 0.643 rs598701 chr2:219387005 C/G cg18887096 chr2:219472410 PLCD4 -0.37 -6.36 -0.33 6.53e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9948 0.655 rs56913233 chr2:97405896 A/G cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs67981189 0.537 rs1978164 chr14:71361367 C/G cg15816911 chr14:71606274 NA -0.41 -6.62 -0.34 1.37e-10 Schizophrenia; LIHC cis rs6500602 0.727 rs10451135 chr16:4580214 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.48 7.4 0.37 1.08e-12 Schizophrenia; LIHC cis rs4891159 0.548 rs689902 chr18:74119969 C/T cg24786174 chr18:74118243 ZNF516 -0.85 -18.17 -0.7 4.19e-52 Longevity; LIHC cis rs939574 1.000 rs1024131 chr2:220117458 G/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.0 10.47 0.49 1.95e-22 Platelet distribution width; LIHC cis rs2204008 0.805 rs4589389 chr12:37946120 C/A cg26384229 chr12:38710491 ALG10B -0.48 -6.74 -0.34 6.74e-11 Bladder cancer; LIHC trans rs1814175 0.645 rs1874969 chr11:49826700 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.91 0.35 2.33e-11 Height; LIHC cis rs589448 0.967 rs634512 chr12:69754012 C/T cg20891283 chr12:69753455 YEATS4 0.95 22.44 0.77 3.39e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs17685 0.753 rs4398845 chr7:75716781 G/A cg01364799 chr7:75623366 TMEM120A -0.48 -7.28 -0.37 2.25e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs2976388 0.669 rs2585135 chr8:143814193 A/G cg06565975 chr8:143823917 SLURP1 -0.37 -6.72 -0.34 7.67e-11 Urinary tract infection frequency; LIHC cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg03806693 chr22:41940476 POLR3H -1.07 -12.28 -0.55 5.65e-29 Vitiligo; LIHC cis rs7945705 0.902 rs7479407 chr11:9023421 C/T cg12365402 chr11:9010492 NRIP3 0.33 8.53 0.42 4.87e-16 Hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26347064 chr19:45211248 CEACAM16 0.39 6.36 0.33 6.29e-10 Pancreatic cancer; LIHC cis rs1577917 0.917 rs1414201 chr6:86500316 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.81 -0.3 1.42e-8 Response to antipsychotic treatment; LIHC cis rs6430585 0.528 rs12476127 chr2:136763242 A/G cg07169764 chr2:136633963 MCM6 1.26 20.28 0.74 1.38e-60 Corneal structure; LIHC cis rs7617773 0.780 rs3731489 chr3:48228906 C/A cg11946769 chr3:48343235 NME6 0.9 11.12 0.52 9.62e-25 Coronary artery disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00435469 chr11:1495117 HCCA2 0.41 6.17 0.32 1.91e-9 Longevity; LIHC cis rs8113308 0.689 rs8112515 chr19:52491250 A/G cg25782003 chr19:52490127 ZNF350 0.62 5.97 0.31 5.98e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg11494091 chr17:61959527 GH2 0.36 6.06 0.31 3.69e-9 Height; LIHC cis rs1559088 0.803 rs10405770 chr19:33616549 C/T cg27124370 chr19:33622961 WDR88 0.53 8.38 0.41 1.38e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9811920 0.609 rs4244711 chr3:99657205 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.15 0.36 5.37e-12 Axial length; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg02990361 chr1:107599529 PRMT6 -0.57 -9.18 -0.44 4.31e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9300255 0.506 rs61388686 chr12:123810873 G/A cg00376283 chr12:123451042 ABCB9 0.62 10.27 0.49 9.42e-22 Neutrophil percentage of white cells; LIHC cis rs6714710 0.603 rs11692010 chr2:98397301 C/T cg26665480 chr2:98280029 ACTR1B 0.44 6.26 0.32 1.17e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs7903847 0.642 rs10786339 chr10:99153076 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 1.000 rs58608483 chr8:58195269 T/G cg02290350 chr8:58132656 NA 0.47 9.32 0.45 1.45e-18 Developmental language disorder (linguistic errors); LIHC cis rs6570726 0.791 rs392612 chr6:145881586 C/G cg05347473 chr6:146136440 FBXO30 -0.4 -6.59 -0.34 1.69e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.850 rs1880670 chr1:109941133 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC trans rs17685 0.712 rs869805 chr7:75688596 C/T cg19862616 chr7:65841803 NCRNA00174 0.92 19.18 0.72 3.65e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7903847 0.642 rs11189196 chr10:99155079 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg24642844 chr7:1081250 C7orf50 -0.95 -9.26 -0.45 2.25e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2073499 0.935 rs2624837 chr3:50205962 A/G cg21659725 chr3:3221576 CRBN -0.61 -6.52 -0.33 2.56e-10 Schizophrenia; LIHC cis rs7208859 0.623 rs7223404 chr17:29107363 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg06238570 chr21:40685208 BRWD1 0.61 7.24 0.36 2.95e-12 Cognitive function; LIHC cis rs34172651 0.876 rs11074653 chr16:24795959 C/T cg00152838 chr16:24741724 TNRC6A -0.48 -6.37 -0.33 6.16e-10 Intelligence (multi-trait analysis); LIHC cis rs11671664 0.732 rs67775326 chr19:46160969 A/G cg13320842 chr19:46175254 GIPR 0.7 11.87 0.54 1.94e-27 Type 2 diabetes;Body mass index;Body mass index (SNP x SNP interaction); LIHC cis rs7208859 0.623 rs8080882 chr17:29081146 G/A cg14067834 chr17:29058358 SUZ12P 0.68 6.69 0.34 9.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs748404 0.697 rs475261 chr15:43546456 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.43 6.57 0.33 1.91e-10 Lung cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07880337 chr3:194304578 NA 0.51 6.62 0.34 1.41e-10 Lung function (FEV1/FVC); LIHC cis rs11583043 1.000 rs12750667 chr1:101498682 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 7.97 0.4 2.34e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4780401 0.539 rs62040604 chr16:11803641 G/A cg01061890 chr16:11836724 TXNDC11 -0.62 -9.8 -0.47 3.88e-20 Rheumatoid arthritis; LIHC cis rs66887589 0.934 rs6817317 chr4:120542827 A/G cg09307838 chr4:120376055 NA -0.46 -6.86 -0.35 3.32e-11 Diastolic blood pressure; LIHC trans rs2243480 1.000 rs1723270 chr7:65469830 T/G cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 2.02e-33 Diabetic kidney disease; LIHC cis rs7116495 1.000 rs4121395 chr11:71669242 C/T cg26138937 chr11:71823887 C11orf51 -0.82 -8.17 -0.4 6.02e-15 Severe influenza A (H1N1) infection; LIHC cis rs5769765 0.773 rs9616206 chr22:50310847 G/T cg09182678 chr22:50328711 NA -0.44 -6.2 -0.32 1.67e-9 Schizophrenia; LIHC cis rs1153858 1.000 rs1554521 chr15:45664189 A/T cg26924012 chr15:45694286 SPATA5L1 -0.93 -18.02 -0.7 1.62e-51 Homoarginine levels; LIHC cis rs11792861 0.926 rs72607172 chr9:111876523 A/G cg05043794 chr9:111880884 C9orf5 -0.3 -6.94 -0.35 1.96e-11 Menarche (age at onset); LIHC cis rs7258465 0.931 rs76195 chr19:18629830 A/G cg01065977 chr19:18549689 ISYNA1 -0.38 -5.91 -0.3 8.25e-9 Breast cancer; LIHC cis rs7927592 0.913 rs6591344 chr11:68360873 G/A cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.94e-14 Total body bone mineral density; LIHC cis rs6445975 0.667 rs34532954 chr3:58243594 C/A cg23715586 chr3:58305044 RPP14 -0.34 -5.74 -0.3 2.13e-8 Systemic lupus erythematosus; LIHC cis rs6120849 0.615 rs11167248 chr20:33538721 G/T cg07148914 chr20:33460835 GGT7 0.51 5.75 0.3 1.94e-8 Protein C levels; LIHC trans rs66573146 0.656 rs57454756 chr4:6958582 C/T cg07817883 chr1:32538562 TMEM39B 1.22 10.2 0.48 1.66e-21 Granulocyte percentage of myeloid white cells; LIHC cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg11301795 chr4:187892539 NA -0.29 -7.8 -0.39 7.47e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs10751667 0.643 rs11246348 chr11:939476 G/C ch.11.42038R chr11:967971 AP2A2 0.53 9.69 0.46 8.55e-20 Alzheimer's disease (late onset); LIHC cis rs17106184 1.000 rs12062764 chr1:51296907 G/A cg07174182 chr1:51127561 FAF1 -0.61 -6.85 -0.35 3.54e-11 Type 2 diabetes; LIHC cis rs9916302 0.861 rs7503514 chr17:37669884 G/C cg15445000 chr17:37608096 MED1 0.38 5.74 0.3 2.05e-8 Glomerular filtration rate (creatinine); LIHC cis rs240110 0.539 rs6934256 chr6:101338728 G/A cg09795085 chr6:101329169 ASCC3 0.57 8.04 0.4 1.44e-14 Neuroticism; LIHC cis rs798554 0.797 rs1182184 chr7:2872446 G/A cg13628971 chr7:2884303 GNA12 0.52 7.24 0.36 3.05e-12 Height; LIHC cis rs3806843 0.676 rs2569159 chr5:140030710 C/T cg16179182 chr5:140090404 VTRNA1-1 0.38 6.21 0.32 1.5e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs17401966 0.838 rs10864449 chr1:10296922 A/T cg19773385 chr1:10388646 KIF1B -0.39 -7.16 -0.36 4.84e-12 Hepatocellular carcinoma; LIHC cis rs425277 0.958 rs262639 chr1:2107061 G/T cg24578937 chr1:2090814 PRKCZ 0.49 8.6 0.42 2.9e-16 Height; LIHC cis rs66782572 1 rs66782572 chr3:52567617 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.21 0.36 3.64e-12 Hemoglobin concentration; LIHC trans rs60843830 1.000 rs7595075 chr2:264019 C/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.68 9.73 0.47 6.69e-20 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs858239 0.539 rs6461695 chr7:23197784 C/A cg18081818 chr7:23246105 NA -0.4 -5.76 -0.3 1.83e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs3106136 0.807 rs6851128 chr4:95259455 A/G cg11021082 chr4:95130006 SMARCAD1 0.41 7.3 0.37 2.07e-12 Capecitabine sensitivity; LIHC cis rs763121 0.853 rs5757166 chr22:38995385 G/T cg06022373 chr22:39101656 GTPBP1 0.75 15.06 0.63 1.09e-39 Menopause (age at onset); LIHC cis rs9814567 1.000 rs9876658 chr3:134179453 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.54 10.08 0.48 4.42e-21 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7618501 0.669 rs7634084 chr3:49949834 A/T cg24110177 chr3:50126178 RBM5 -0.48 -7.7 -0.38 1.52e-13 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.692 rs12911174 chr15:77149943 G/A cg03037974 chr15:76606532 NA 0.74 14.5 0.62 1.73e-37 Blood metabolite levels; LIHC cis rs7959452 0.719 rs57954211 chr12:69748397 C/A cg22834771 chr12:69754056 YEATS4 -0.5 -8.59 -0.42 3.19e-16 Blood protein levels; LIHC trans rs4927850 0.752 rs7624460 chr3:195748530 C/T cg16724585 chr3:197361211 NA -0.42 -6.15 -0.32 2.11e-9 Pancreatic cancer; LIHC cis rs2637266 0.935 rs1978927 chr10:78399786 A/T cg18941641 chr10:78392320 NA 0.28 6.24 0.32 1.32e-9 Pulmonary function; LIHC trans rs933688 0.527 rs1511344 chr5:90582914 G/C cg19365810 chr7:152064079 MLL3 0.42 6.27 0.32 1.1e-9 Smoking behavior; LIHC cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs425277 1.000 rs1401138 chr1:2063149 C/T cg24578937 chr1:2090814 PRKCZ 0.46 7.79 0.39 8.2e-14 Height; LIHC trans rs10213084 1.000 rs28617320 chr4:147480098 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.51 6.1 0.31 2.81e-9 Heart rate; LIHC cis rs4930103 0.935 rs2071094 chr11:2021164 G/T cg06197492 chr11:2016605 H19 0.38 6.04 0.31 3.94e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg11644478 chr21:40555479 PSMG1 -0.38 -5.89 -0.3 9.21e-9 Cognitive function; LIHC cis rs929354 0.709 rs1182363 chr7:157019151 A/G cg16102536 chr7:156981717 UBE3C -0.36 -6.14 -0.32 2.25e-9 Body mass index; LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.28 0.32 1.02e-9 Renal cell carcinoma; LIHC cis rs11958404 0.932 rs11950881 chr5:157410550 C/T cg05962755 chr5:157440814 NA 0.93 10.14 0.48 2.62e-21 IgG glycosylation; LIHC cis rs7552404 0.731 rs6699682 chr1:76340123 A/G cg10523679 chr1:76189770 ACADM -0.56 -6.81 -0.35 4.48e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs12497850 0.931 rs7621015 chr3:49016056 A/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.19 0.36 4.06e-12 Parkinson's disease; LIHC trans rs867371 1.000 rs13380319 chr15:82506867 G/T cg18393722 chr15:85113863 UBE2QP1 -0.41 -6.93 -0.35 2.16e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs72829446 0.530 rs2228132 chr17:7411770 C/T cg02795151 chr17:7402630 POLR2A 0.54 6.24 0.32 1.29e-9 Androgen levels; LIHC cis rs35883536 0.514 rs4908062 chr1:101013211 T/C cg14515779 chr1:101123966 NA -0.48 -6.8 -0.35 4.71e-11 Monocyte count; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg06207460 chr9:4741011 AK3 -0.47 -6.12 -0.31 2.6e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1385374 0.858 rs11059923 chr12:129293057 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -5.95 -0.31 6.49e-9 Systemic lupus erythematosus; LIHC cis rs2795502 0.873 rs1815716 chr10:43410200 G/A cg27426351 chr10:43362370 NA 0.47 5.75 0.3 1.95e-8 Blood protein levels; LIHC cis rs459571 0.959 rs378740 chr9:136890876 C/A cg13789015 chr9:136890014 NCRNA00094 0.44 7.99 0.4 2.1e-14 Platelet distribution width; LIHC cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg12463550 chr7:65579703 CRCP -0.66 -6.85 -0.35 3.41e-11 Diabetic kidney disease; LIHC cis rs6424115 1.000 rs1018396 chr1:24133612 G/A cg15997130 chr1:24165203 NA 0.47 9.68 0.46 9.79e-20 Immature fraction of reticulocytes; LIHC cis rs1005277 0.579 rs1780122 chr10:38529509 C/A cg18963800 chr10:38644991 HSD17B7P2 -0.43 -6.34 -0.32 7.08e-10 Extrinsic epigenetic age acceleration; LIHC cis rs858239 0.601 rs2068459 chr7:23154313 A/C cg18081818 chr7:23246105 NA -0.4 -6.03 -0.31 4.26e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2463822 0.844 rs2513737 chr11:62119495 G/C cg06239285 chr11:62104954 ASRGL1 0.91 6.85 0.35 3.55e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs12701220 0.522 rs12701455 chr7:1055409 A/G cg00990874 chr7:1149470 C7orf50 -0.55 -8.16 -0.4 6.37e-15 Bronchopulmonary dysplasia; LIHC cis rs1865760 1.000 rs9393675 chr6:25930116 G/A cg17691542 chr6:26056736 HIST1H1C 0.41 6.17 0.32 1.88e-9 Height; LIHC cis rs9300255 0.543 rs520088 chr12:123522150 C/G cg05973401 chr12:123451056 ABCB9 0.45 5.82 0.3 1.36e-8 Neutrophil percentage of white cells; LIHC trans rs1406428 0.748 rs1919427 chr2:51735494 C/T cg26190225 chr4:71570509 RUFY3 -0.63 -6.22 -0.32 1.48e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs9303401 0.659 rs3809724 chr17:57061238 G/A cg25039879 chr17:56429692 SUPT4H1 0.83 9.38 0.45 9.11e-19 Cognitive test performance; LIHC cis rs6061231 0.546 rs482220 chr20:60927482 G/A cg06026331 chr20:60912101 LAMA5 -0.53 -8.72 -0.43 1.21e-16 Colorectal cancer; LIHC cis rs2239547 0.563 rs6797399 chr3:52905917 G/A cg11645453 chr3:52864694 ITIH4 0.32 8.06 0.4 1.26e-14 Schizophrenia; LIHC cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.2 -0.36 3.84e-12 Bipolar disorder; LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg17158414 chr2:27665306 KRTCAP3 -0.42 -5.84 -0.3 1.22e-8 Total body bone mineral density; LIHC cis rs763121 0.853 rs6001184 chr22:39052116 C/T cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs1577917 1.000 rs12203924 chr6:86776412 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.31 -0.37 1.84e-12 Response to antipsychotic treatment; LIHC cis rs11167764 0.945 rs7720832 chr5:141473097 T/G cg23435118 chr5:141488016 NDFIP1 -0.43 -5.77 -0.3 1.8e-8 Crohn's disease; LIHC cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg11764359 chr7:65958608 NA 0.69 9.44 0.45 5.86e-19 Calcium levels; LIHC cis rs250677 0.687 rs250666 chr5:148454622 A/G cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs2302190 0.882 rs6503869 chr17:56637461 C/G cg12560992 chr17:57184187 TRIM37 0.68 8.8 0.43 7e-17 Vitamin D levels; LIHC cis rs769267 0.931 rs2965197 chr19:19470910 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.58 -9.19 -0.45 3.81e-18 Tonsillectomy; LIHC cis rs9486719 1.000 rs12208449 chr6:96903253 A/G cg06623918 chr6:96969491 KIAA0776 0.63 6.42 0.33 4.57e-10 Migraine;Coronary artery disease; LIHC cis rs79387448 0.745 rs7587856 chr2:103144305 C/A cg09003973 chr2:102972529 NA 0.85 7.47 0.37 6.82e-13 Gut microbiota (bacterial taxa); LIHC cis rs6450176 0.680 rs255756 chr5:53309364 A/G ch.5.1024479R chr5:53302184 ARL15 -1.0 -17.95 -0.7 3.13e-51 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1568889 1.000 rs12804198 chr11:28143114 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.91 0.35 2.36e-11 Bipolar disorder; LIHC cis rs903552 1.000 rs8041563 chr15:102005824 G/C cg00659931 chr15:102010125 PCSK6 -0.46 -6.2 -0.32 1.63e-9 Diabetic kidney disease; LIHC trans rs1814175 0.618 rs7483546 chr11:49714784 C/A cg03929089 chr4:120376271 NA -0.85 -16.55 -0.67 1.36e-45 Height; LIHC cis rs798554 0.759 rs1182189 chr7:2869522 G/A cg13628971 chr7:2884303 GNA12 0.52 6.92 0.35 2.27e-11 Height; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.958 rs1816937 chr6:86557251 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.07 -0.4 1.22e-14 Response to antipsychotic treatment; LIHC cis rs4819052 1.000 rs28628220 chr21:46663741 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.71 9.44 0.45 6.1e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2067615 0.579 rs10861667 chr12:107194776 T/G cg15890332 chr12:107067104 RFX4 0.26 6.09 0.31 3.08e-9 Heart rate; LIHC cis rs896854 0.812 rs2340586 chr8:95969261 G/A cg13393036 chr8:95962371 TP53INP1 -0.37 -8.54 -0.42 4.32e-16 Type 2 diabetes; LIHC cis rs1580019 0.563 rs34201720 chr7:32568935 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.61 8.98 0.44 1.9e-17 Cognitive ability; LIHC cis rs509477 0.718 rs273353 chr18:32599361 G/A cg23791764 chr18:32556832 MAPRE2 0.45 6.1 0.31 2.81e-9 Cerebrospinal fluid AB1-42 levels; LIHC cis rs7927592 0.763 rs10896326 chr11:68234571 T/C cg16797656 chr11:68205561 LRP5 0.52 9.15 0.44 5.38e-18 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06866400 chr6:143771904 ADAT2;PEX3 -0.42 -6.17 -0.32 1.89e-9 Pancreatic cancer; LIHC cis rs79387448 0.655 rs76930359 chr2:102924684 G/A cg09003973 chr2:102972529 NA 1.21 9.74 0.47 6.08e-20 Gut microbiota (bacterial taxa); LIHC trans rs8073060 0.586 rs6505486 chr17:33996776 G/A cg19694781 chr19:47549865 TMEM160 -1.25 -13.17 -0.58 2.47e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.56 8.36 0.41 1.66e-15 Height; LIHC cis rs4969178 0.931 rs3826323 chr17:76400268 C/G cg20026190 chr17:76395443 PGS1 0.45 7.12 0.36 6.52e-12 HDL cholesterol levels; LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.47 0.62 2.34e-37 Prudent dietary pattern; LIHC cis rs7208859 0.623 rs9899692 chr17:29156939 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.7 0.34 8.36e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs55882075 0.535 rs67484565 chr5:179110574 G/T cg14593053 chr5:179126677 CANX 0.37 6.43 0.33 4.28e-10 Monocyte percentage of white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04844971 chr15:50979486 TRPM7 0.45 6.41 0.33 4.79e-10 Pancreatic cancer; LIHC cis rs4332037 0.707 rs56070303 chr7:1891015 C/T cg23422044 chr7:1970798 MAD1L1 -0.54 -6.5 -0.33 2.9e-10 Bipolar disorder; LIHC cis rs6952808 0.782 rs4236271 chr7:1881369 C/T cg14004847 chr7:1930337 MAD1L1 -0.51 -7.59 -0.38 3.07e-13 Bipolar disorder and schizophrenia; LIHC cis rs10911232 0.507 rs4072709 chr1:183028855 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.53 0.49 1.21e-22 Hypertriglyceridemia; LIHC cis rs17102423 0.755 rs942627 chr14:65550025 A/G cg11161011 chr14:65562177 MAX -0.53 -7.58 -0.38 3.19e-13 Obesity-related traits; LIHC cis rs919433 0.713 rs10172961 chr2:198446859 T/C cg03934865 chr2:198174659 NA 0.52 7.86 0.39 4.89e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg03517284 chr6:25882590 NA -0.64 -8.97 -0.44 1.95e-17 Blood metabolite levels; LIHC cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs875971 1.000 rs778706 chr7:65860424 A/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs7131987 0.650 rs3782509 chr12:29453778 G/A cg05697976 chr12:29376483 FAR2 0.29 5.96 0.31 6.37e-9 QT interval; LIHC cis rs2976388 0.967 rs2976393 chr8:143763618 C/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC trans rs8113308 0.810 rs8100521 chr19:52449643 A/G cg14959425 chr7:20447707 ITGB8 -0.47 -6.11 -0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs72627123 0.867 rs73303107 chr14:74477284 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.63 0.46 1.42e-19 Morning vs. evening chronotype; LIHC cis rs7937682 1.000 rs9734135 chr11:111536190 G/A cg09085632 chr11:111637200 PPP2R1B -1.02 -12.99 -0.57 1.25e-31 Primary sclerosing cholangitis; LIHC cis rs9486719 1.000 rs11752584 chr6:96884952 C/A cg06623918 chr6:96969491 KIAA0776 -0.72 -7.15 -0.36 5.19e-12 Migraine;Coronary artery disease; LIHC cis rs4974559 1.000 rs4974559 chr4:1380848 C/T cg05025164 chr4:1340916 KIAA1530 -0.49 -6.83 -0.35 3.99e-11 Systolic blood pressure; LIHC cis rs11792861 0.855 rs72607165 chr9:111814498 C/T cg13535736 chr9:111863775 C9orf5 -0.4 -5.99 -0.31 5.37e-9 Menarche (age at onset); LIHC cis rs25645 0.502 rs17609240 chr17:38110689 T/G cg17344932 chr17:38183730 MED24;SNORD124 -0.5 -7.43 -0.37 8.75e-13 Myeloid white cell count; LIHC cis rs8064299 0.967 rs878906 chr17:72769334 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.73 12.4 0.56 1.98e-29 Monocyte count; LIHC cis rs6976053 0.518 rs314358 chr7:100410657 A/G cg03098644 chr7:100410630 EPHB4 -0.42 -6.78 -0.34 5.28e-11 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC cis rs561341 1.000 rs498391 chr17:30328704 G/A cg00745463 chr17:30367425 LRRC37B -0.77 -5.81 -0.3 1.45e-8 Hip circumference adjusted for BMI; LIHC cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -11.52 -0.53 3.52e-26 Platelet count; LIHC cis rs9916302 0.851 rs12936996 chr17:37665554 A/G cg00129232 chr17:37814104 STARD3 0.42 6.65 0.34 1.17e-10 Glomerular filtration rate (creatinine); LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg11070056 chr1:107600091 PRMT6 0.68 11.42 0.53 8.6e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9733 0.596 rs6587516 chr1:150623221 C/T cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs7572733 0.534 rs7572123 chr2:198769637 A/G cg10820045 chr2:198174542 NA 0.48 7.31 0.37 1.88e-12 Dermatomyositis; LIHC cis rs10504229 1.000 rs59843034 chr8:58195756 T/G cg02290350 chr8:58132656 NA 0.47 9.16 0.44 4.93e-18 Developmental language disorder (linguistic errors); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00124920 chr1:178515751 C1orf220 0.4 6.14 0.32 2.24e-9 Longevity; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs2274273 0.901 rs68046603 chr14:55762803 T/A cg01864836 chr14:55583639 NA -0.37 -6.46 -0.33 3.52e-10 Protein biomarker; LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg17178900 chr1:205818956 PM20D1 0.73 10.56 0.5 9.52e-23 Menarche (age at onset); LIHC cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg22105103 chr4:187893119 NA 0.3 7.46 0.37 7.32e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.42 -5.91 -0.3 8.4e-9 Colorectal cancer; LIHC cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg04944784 chr2:26401820 FAM59B -0.71 -9.13 -0.44 6.13e-18 Gut microbiome composition (summer); LIHC cis rs716804 0.740 rs7116147 chr11:10287310 A/G cg01453529 chr11:10209919 SBF2 -0.29 -5.87 -0.3 1.01e-8 Neuroticism; LIHC cis rs4474465 0.915 rs10899503 chr11:78149961 C/T cg27205649 chr11:78285834 NARS2 -0.39 -6.0 -0.31 5.01e-9 Alzheimer's disease (survival time); LIHC cis rs17152411 0.652 rs2114834 chr10:126650186 A/G cg07906193 chr10:126599966 NA -0.35 -7.01 -0.35 1.31e-11 Height; LIHC cis rs9814567 0.752 rs4605591 chr3:134328361 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.62 -0.46 1.53e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg06212747 chr3:49208901 KLHDC8B 0.58 7.55 0.38 3.96e-13 Parkinson's disease; LIHC cis rs7474896 0.515 rs2738208 chr10:38306128 A/G cg25427524 chr10:38739819 LOC399744 0.45 5.9 0.3 8.53e-9 Obesity (extreme); LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.9 0.39 3.89e-14 Prudent dietary pattern; LIHC cis rs7208859 0.623 rs11658022 chr17:29085359 A/T cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 8.11e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4919087 0.683 rs1687372 chr10:98978185 A/T cg25902810 chr10:99078978 FRAT1 -0.55 -6.28 -0.32 1.01e-9 Monocyte count; LIHC cis rs7103648 0.618 rs11039284 chr11:47564785 A/G cg20307385 chr11:47447363 PSMC3 0.89 12.47 0.56 1.12e-29 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs6951245 0.832 rs79808627 chr7:1092519 C/G cg24642844 chr7:1081250 C7orf50 -0.8 -8.37 -0.41 1.52e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1577917 0.958 rs11758508 chr6:86506878 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.39 6.38 0.33 5.72e-10 Response to antipsychotic treatment; LIHC cis rs8062405 1.000 rs62036657 chr16:28844365 G/A cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg03806693 chr22:41940476 POLR3H -0.97 -10.29 -0.49 8.32e-22 Vitiligo; LIHC cis rs6500602 0.727 rs4786515 chr16:4578133 T/A cg08645402 chr16:4508243 NA 0.44 8.22 0.41 4.19e-15 Schizophrenia; LIHC cis rs2991971 1.000 rs622798 chr1:46015271 T/G cg03146154 chr1:46216737 IPP -0.38 -5.85 -0.3 1.13e-8 High light scatter reticulocyte count; LIHC cis rs8084351 0.577 rs12454410 chr18:50655969 T/C cg24270629 chr18:50823537 DCC -0.43 -6.36 -0.33 6.41e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs13108904 0.560 rs11247994 chr4:1343720 G/A cg22903657 chr4:1355424 KIAA1530 -0.43 -6.34 -0.32 7.4e-10 Obesity-related traits; LIHC cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg03264133 chr6:25882463 NA -1.09 -17.39 -0.69 5.58e-49 Urate levels; LIHC trans rs2832191 0.692 rs2245734 chr21:30359965 C/T cg14791747 chr16:20752902 THUMPD1 -0.49 -6.86 -0.35 3.2e-11 Dental caries; LIHC cis rs10911251 0.528 rs6669199 chr1:183082421 C/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.72 0.5 2.59e-23 Colorectal cancer; LIHC cis rs13040088 1.000 rs910831 chr20:61558775 T/C cg23096297 chr20:61557774 DIDO1 0.85 11.56 0.53 2.51e-26 Menopause (age at onset); LIHC trans rs1005277 0.522 rs9417256 chr10:37976990 A/G cg17830980 chr10:43048298 ZNF37B -0.42 -8.17 -0.4 6.05e-15 Extrinsic epigenetic age acceleration; LIHC cis rs35110281 0.720 rs230647 chr21:44919654 C/T cg04455712 chr21:45112962 RRP1B -0.45 -6.91 -0.35 2.39e-11 Mean corpuscular volume; LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg13409248 chr3:40428643 ENTPD3 0.5 8.4 0.41 1.24e-15 Renal cell carcinoma; LIHC cis rs6120849 0.707 rs3746444 chr20:33578251 A/G cg24642439 chr20:33292090 TP53INP2 0.63 7.11 0.36 6.83e-12 Protein C levels; LIHC cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg21448741 chr8:58168803 NA 0.37 6.63 0.34 1.29e-10 Developmental language disorder (linguistic errors); LIHC cis rs7249142 0.549 rs62135499 chr19:19294237 T/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.42 -6.99 -0.35 1.44e-11 IgG glycosylation; LIHC cis rs7927592 0.956 rs7944870 chr11:68309108 C/G cg20283391 chr11:68216788 NA -0.51 -7.79 -0.39 7.91e-14 Total body bone mineral density; LIHC cis rs35883536 0.626 rs10493933 chr1:101111282 A/G cg14515779 chr1:101123966 NA 0.51 8.14 0.4 7.5e-15 Monocyte count; LIHC cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.554 rs3732963 chr3:10048885 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC cis rs2637266 0.905 rs34173296 chr10:78343389 C/T cg18941641 chr10:78392320 NA 0.29 5.96 0.31 6.27e-9 Pulmonary function; LIHC cis rs4654899 0.758 rs6426665 chr1:21382205 T/C cg08539965 chr1:21396338 EIF4G3 0.33 5.83 0.3 1.31e-8 Superior frontal gyrus grey matter volume; LIHC cis rs875971 0.895 rs12531677 chr7:65769086 G/A cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC trans rs2243480 1.000 rs34970380 chr7:65431493 C/T cg10756647 chr7:56101905 PSPH 1.11 13.47 0.59 1.75e-33 Diabetic kidney disease; LIHC cis rs2816062 0.813 rs2816050 chr1:18894432 A/G cg18795169 chr1:18902165 NA -0.8 -18.23 -0.7 2.41e-52 Urate levels in lean individuals; LIHC cis rs1005277 0.579 rs2474608 chr10:38457109 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs7091068 0.518 rs913045 chr10:95431535 C/T cg20715218 chr10:95462985 C10orf4 0.53 7.65 0.38 2.05e-13 Urinary tract infection frequency; LIHC cis rs7616330 0.790 rs2140131 chr3:71044545 A/G cg01511742 chr3:71112437 FOXP1 -0.45 -6.11 -0.31 2.69e-9 QT interval; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.93 0.57 2.1e-31 Prudent dietary pattern; LIHC cis rs4891159 0.513 rs2554831 chr18:74113513 C/G cg24786174 chr18:74118243 ZNF516 0.84 16.76 0.67 1.92e-46 Longevity; LIHC cis rs6089829 0.962 rs6122350 chr20:61664617 A/G cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC trans rs17685 0.633 rs3801471 chr7:75696188 T/G cg19862616 chr7:65841803 NCRNA00174 0.93 18.77 0.71 1.55e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2295359 1.000 rs11209007 chr1:67619345 C/G cg12940439 chr1:67600707 NA 0.4 7.24 0.36 2.96e-12 Psoriasis; LIHC cis rs6141600 0.760 rs2746097 chr20:34672923 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.37 -5.73 -0.3 2.19e-8 Height;Hip circumference; LIHC cis rs311392 0.902 rs448238 chr8:55093655 C/T cg20636351 chr8:55087400 NA 0.34 7.18 0.36 4.46e-12 Pelvic organ prolapse (moderate/severe); LIHC trans rs9929218 0.861 rs8056206 chr16:68802072 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -8.67 -0.42 1.83e-16 Colorectal cancer; LIHC trans rs7246657 0.943 rs10405407 chr19:37839164 C/T cg10208301 chr11:6592745 DNHD1 0.48 6.96 0.35 1.71e-11 Coronary artery calcification; LIHC cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg06634786 chr22:41940651 POLR3H -0.75 -7.82 -0.39 6.8e-14 Vitiligo; LIHC cis rs10504073 0.647 rs11997959 chr8:50014044 C/T cg00325661 chr8:49890786 NA 0.32 7.23 0.36 3.19e-12 Blood metabolite ratios; LIHC cis rs12620999 1.000 rs4558538 chr2:238055975 C/T cg23555395 chr2:238036564 NA -0.31 -5.8 -0.3 1.47e-8 Systemic lupus erythematosus; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg04234412 chr22:24373322 LOC391322 -0.73 -11.18 -0.52 6.3e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9790314 0.503 rs6441374 chr3:161064540 A/T cg17135325 chr3:160939158 NMD3 0.52 7.34 0.37 1.61e-12 Morning vs. evening chronotype; LIHC cis rs17685 0.702 rs6960598 chr7:75772991 T/C cg16684958 chr7:75615977 POR 0.4 6.57 0.33 1.87e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7639513 0.767 rs2348201 chr3:12711696 A/G cg23032965 chr3:12705835 RAF1 0.66 8.01 0.4 1.81e-14 Itch intensity from mosquito bite; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17074969 chr3:14220346 LSM3;XPC -0.48 -6.34 -0.32 7.13e-10 Pancreatic cancer; LIHC cis rs12594515 1.000 rs12592190 chr15:45994028 G/A cg01629716 chr15:45996671 NA 0.51 9.16 0.44 4.72e-18 Waist circumference;Weight; LIHC cis rs4423214 0.959 rs12800438 chr11:71171003 G/A cg24826892 chr11:71159390 DHCR7 0.47 6.12 0.31 2.55e-9 Vitamin D levels; LIHC cis rs1707322 0.963 rs6666763 chr1:46436451 C/A cg06784218 chr1:46089804 CCDC17 0.37 6.56 0.33 2e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2075371 0.829 rs727202 chr7:133947942 A/G cg11752832 chr7:134001865 SLC35B4 0.47 6.03 0.31 4.15e-9 Mean platelet volume; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01083598 chr16:54155993 NA 0.49 6.88 0.35 2.88e-11 Hepatitis; LIHC cis rs7000551 0.751 rs2461481 chr8:22382780 A/G cg12081754 chr8:22256438 SLC39A14 -0.4 -5.9 -0.3 8.88e-9 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs4727027 0.868 rs10952799 chr7:148840772 C/T cg23583168 chr7:148888333 NA -0.74 -10.65 -0.5 4.5e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6754311 0.731 rs7579771 chr2:136580260 T/A cg17750252 chr2:136567154 LCT -0.35 -6.41 -0.33 4.7e-10 Mosquito bite size; LIHC cis rs459571 1.000 rs459571 chr9:136912626 C/T cg13789015 chr9:136890014 NCRNA00094 0.46 8.26 0.41 3.15e-15 Platelet distribution width; LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg16132339 chr22:24313637 DDTL;DDT 0.73 14.3 0.61 1.14e-36 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9303401 0.573 rs34097494 chr17:57171917 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.46 0.56 1.25e-29 Cognitive test performance; LIHC cis rs6429082 0.818 rs291386 chr1:235647050 C/T cg26050004 chr1:235667680 B3GALNT2 0.48 7.34 0.37 1.56e-12 Adiposity; LIHC cis rs7020830 0.898 rs6476617 chr9:37200103 G/A cg14294708 chr9:37120828 ZCCHC7 1.09 23.82 0.79 1.3e-74 Schizophrenia; LIHC cis rs2842992 0.915 rs2758350 chr6:160118056 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.7 11.85 0.54 2.34e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs7829975 0.902 rs777707 chr8:8584344 A/G cg06636001 chr8:8085503 FLJ10661 0.48 7.57 0.38 3.42e-13 Mood instability; LIHC cis rs2439831 0.867 rs2245715 chr15:43818052 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.7 11.07 0.51 1.46e-24 Lung cancer in ever smokers; LIHC cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg12463550 chr7:65579703 CRCP 0.7 7.4 0.37 1.04e-12 Diabetic kidney disease; LIHC trans rs4650994 0.525 rs2493848 chr1:178547838 T/A cg05059571 chr16:84539110 KIAA1609 0.45 7.66 0.38 1.95e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs769267 1.000 rs7246748 chr19:19433105 C/T cg03709012 chr19:19516395 GATAD2A -0.91 -15.52 -0.64 1.65e-41 Tonsillectomy; LIHC cis rs908922 0.676 rs6674451 chr1:152531054 C/T cg20991723 chr1:152506922 NA 0.53 8.76 0.43 9.49e-17 Hair morphology; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.13 0.55 2e-28 Prudent dietary pattern; LIHC cis rs2932538 0.961 rs6537747 chr1:113179597 C/T cg22162597 chr1:113214053 CAPZA1 -0.68 -10.8 -0.5 1.39e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.86 0.39 5.2e-14 Prudent dietary pattern; LIHC cis rs7582180 0.676 rs11680660 chr2:100931738 G/C cg14675211 chr2:100938903 LONRF2 0.56 8.7 0.43 1.44e-16 Intelligence (multi-trait analysis); LIHC cis rs6691722 0.583 rs35671964 chr1:24695749 C/G cg18323236 chr1:24743029 NIPAL3 0.35 6.39 0.33 5.44e-10 Response to interferon beta in multiple sclerosis; LIHC cis rs533581 0.816 rs1559446 chr16:88975332 A/G cg03970086 chr16:88974840 CBFA2T3 0.34 6.52 0.33 2.56e-10 Social autistic-like traits; LIHC cis rs2836974 0.644 rs9978775 chr21:40694526 A/G cg06238570 chr21:40685208 BRWD1 -0.55 -8.9 -0.43 3.36e-17 Cognitive function; LIHC cis rs3741151 1.000 rs7122825 chr11:73061324 C/T cg17517138 chr11:73019481 ARHGEF17 0.91 6.76 0.34 5.85e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs7662987 0.517 rs2602876 chr4:100039535 A/T cg13256891 chr4:100009986 ADH5 0.56 5.79 0.3 1.61e-8 Smoking initiation; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg26338869 chr17:61819248 STRADA 0.6 8.57 0.42 3.65e-16 Prudent dietary pattern; LIHC cis rs35306767 0.953 rs12259801 chr10:959306 C/G cg20503657 chr10:835505 NA 0.9 10.77 0.5 1.76e-23 Eosinophil percentage of granulocytes; LIHC cis rs644799 0.965 rs11021313 chr11:95506907 G/C cg25478527 chr11:95522999 CEP57;FAM76B 0.41 5.74 0.3 2.08e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs1577917 0.958 rs12190603 chr6:86475718 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.29 -0.41 2.65e-15 Response to antipsychotic treatment; LIHC cis rs2731664 0.740 rs2731670 chr5:176848019 G/T cg23176889 chr5:176863531 GRK6 0.62 11.29 0.52 2.46e-25 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg05564831 chr3:52568323 NT5DC2 0.37 6.02 0.31 4.57e-9 Electroencephalogram traits; LIHC cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg12379764 chr21:47803548 PCNT -0.63 -8.66 -0.42 1.88e-16 Testicular germ cell tumor; LIHC cis rs4713118 0.587 rs9393899 chr6:28133528 G/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Parkinson's disease; LIHC cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs79387448 0.745 rs1159509 chr2:103169073 T/A cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg05025164 chr4:1340916 KIAA1530 0.41 6.37 0.33 6.05e-10 Obesity-related traits; LIHC cis rs9916302 0.904 rs8079560 chr17:37497661 C/T cg03013999 chr17:37608204 MED1 -0.36 -5.99 -0.31 5.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs1395 0.778 rs724311 chr2:27441645 A/G cg23587288 chr2:27483067 SLC30A3 -0.32 -6.03 -0.31 4.19e-9 Blood metabolite levels; LIHC cis rs490234 0.552 rs3122938 chr9:128157326 A/G cg14078157 chr9:128172775 NA 0.44 7.91 0.39 3.62e-14 Mean arterial pressure; LIHC cis rs2346177 0.542 rs6718875 chr2:46687982 G/T cg02822958 chr2:46747628 ATP6V1E2 0.47 6.92 0.35 2.3e-11 HDL cholesterol; LIHC cis rs11098499 0.954 rs10518328 chr4:120401779 G/A cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.65e-29 Corneal astigmatism; LIHC cis rs12497850 0.897 rs9681717 chr3:48872998 A/G cg07636037 chr3:49044803 WDR6 0.93 16.69 0.67 3.76e-46 Parkinson's disease; LIHC cis rs16828019 0.640 rs1140227 chr1:41493811 C/T cg03962019 chr1:41807865 NA 0.5 7.06 0.36 9.29e-12 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.527 rs34835800 chr17:56764990 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.88 10.7 0.5 2.97e-23 Cognitive test performance; LIHC cis rs11190604 0.767 rs12360395 chr10:102194074 A/T cg07080220 chr10:102295463 HIF1AN 0.47 6.85 0.35 3.41e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10792665 0.640 rs114349340 chr11:82629151 T/C cg24227371 chr11:82718527 RAB30 -0.27 -6.13 -0.31 2.41e-9 Obesity-related traits; LIHC cis rs6088580 0.524 rs4911437 chr20:33266149 G/T cg07148914 chr20:33460835 GGT7 -0.52 -7.3 -0.37 2.03e-12 Glomerular filtration rate (creatinine); LIHC trans rs873946 0.504 rs4880275 chr10:134576552 C/T cg02418909 chr7:4811322 NA -0.44 -6.09 -0.31 3.1e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16993936 chr10:13146903 OPTN 0.46 7.03 0.36 1.1e-11 Longevity; LIHC trans rs1814175 0.645 rs10839448 chr11:49938930 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -19.79 -0.73 1.21e-58 Height; LIHC cis rs9430161 0.579 rs11121667 chr1:11038476 C/T cg02454025 chr1:11042201 C1orf127 0.73 13.97 0.6 2.03e-35 Ewing sarcoma; LIHC cis rs1534166 0.647 rs7355929 chr3:133514190 C/T cg12373951 chr3:133503437 NA -0.5 -7.11 -0.36 6.64e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs6782228 0.606 rs7613073 chr3:128388503 T/G cg16766828 chr3:128327626 NA -0.42 -6.59 -0.34 1.64e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg00656387 chr3:40428638 ENTPD3 0.49 8.3 0.41 2.38e-15 Renal cell carcinoma; LIHC cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg25072359 chr17:41440525 NA 0.4 6.32 0.32 7.97e-10 Menopause (age at onset); LIHC cis rs332507 0.830 rs12639478 chr3:124404958 T/A cg05980111 chr3:124395277 KALRN 0.45 6.91 0.35 2.34e-11 Plateletcrit; LIHC cis rs7100689 0.646 rs7098045 chr10:82123856 G/C cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs35160687 0.644 rs11680025 chr2:86545338 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.35 5.74 0.3 2.08e-8 Night sleep phenotypes; LIHC cis rs12824058 0.707 rs2398509 chr12:130816464 T/C cg26677194 chr12:130822605 PIWIL1 0.53 7.23 0.36 3.17e-12 Menopause (age at onset); LIHC cis rs1639906 0.895 rs3800926 chr7:2205956 G/A cg04267008 chr7:1944627 MAD1L1 0.46 6.1 0.31 2.86e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg00149659 chr3:10157352 C3orf10 0.68 7.12 0.36 6.57e-12 Alzheimer's disease; LIHC cis rs10504073 0.669 rs11779189 chr8:50030592 C/G cg00325661 chr8:49890786 NA -0.25 -5.83 -0.3 1.28e-8 Blood metabolite ratios; LIHC cis rs1185460 0.967 rs4454730 chr11:118937444 G/A cg23280166 chr11:118938394 VPS11 0.6 8.31 0.41 2.35e-15 Coronary artery disease; LIHC cis rs4908768 0.906 rs2144463 chr1:8583293 C/A cg20416874 chr1:8611966 RERE 0.57 8.7 0.43 1.42e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs477692 1.000 rs508303 chr10:131424996 A/T cg19680672 chr10:131412579 MGMT 0.42 6.4 0.33 5.01e-10 Response to temozolomide; LIHC cis rs875971 0.545 rs10950029 chr7:65634321 A/C cg11764359 chr7:65958608 NA 0.5 6.99 0.35 1.48e-11 Aortic root size; LIHC cis rs10838687 1.000 rs10838687 chr11:47312892 T/G cg26139080 chr11:47293733 MADD -0.43 -6.29 -0.32 9.45e-10 Proinsulin levels; LIHC cis rs963731 0.579 rs1454226 chr2:39246862 A/G cg04010122 chr2:39346883 SOS1 -0.68 -5.84 -0.3 1.19e-8 Corticobasal degeneration; LIHC cis rs6570726 0.755 rs2103633 chr6:145894021 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.14 0.31 2.35e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1577917 0.655 rs6454472 chr6:86224053 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.21 0.32 1.53e-9 Response to antipsychotic treatment; LIHC cis rs1008375 1.000 rs3846357 chr4:17635887 A/T cg04450456 chr4:17643702 FAM184B 0.34 5.73 0.3 2.17e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2108225 0.900 rs7805114 chr7:107450033 G/T cg18560240 chr7:107437656 SLC26A3 0.41 6.43 0.33 4.21e-10 Ulcerative colitis; LIHC cis rs7772486 0.875 rs2748498 chr6:146319166 C/G cg23711669 chr6:146136114 FBXO30 0.66 11.5 0.53 4.24e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2279817 0.818 rs11582250 chr1:17994234 G/A cg21791023 chr1:18019539 ARHGEF10L -0.41 -5.8 -0.3 1.49e-8 Neuroticism; LIHC cis rs12286929 0.702 rs11215419 chr11:115081810 A/T cg04055981 chr11:115044050 NA 0.48 7.48 0.37 6.37e-13 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs826838 1.000 rs11183196 chr12:38685915 G/T cg13010199 chr12:38710504 ALG10B 0.64 7.76 0.39 9.75e-14 Heart rate; LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.65 0.38 2.03e-13 Height; LIHC trans rs875971 0.545 rs316324 chr7:65610614 A/G cg26939375 chr7:64535504 NA -0.41 -6.47 -0.33 3.32e-10 Aortic root size; LIHC cis rs9457247 0.663 rs9459845 chr6:167440501 C/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.73 -0.43 1.13e-16 Crohn's disease; LIHC cis rs11758351 0.789 rs4496782 chr6:26184617 T/C cg03854865 chr6:26224070 HIST1H3E 0.47 5.96 0.31 6.11e-9 Gout;Renal underexcretion gout; LIHC cis rs2153535 0.580 rs969421 chr6:8451949 A/C cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC cis rs9303401 0.659 rs17822807 chr17:56687190 A/C cg25039879 chr17:56429692 SUPT4H1 0.84 9.58 0.46 1.99e-19 Cognitive test performance; LIHC cis rs243505 0.624 rs6975291 chr7:148548393 C/G cg09806900 chr7:148480153 CUL1 0.43 6.09 0.31 3.02e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2191566 0.664 rs3810406 chr19:44556381 G/T cg20607764 chr19:44506953 ZNF230 -0.37 -6.19 -0.32 1.7e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.27 0.32 1.07e-9 Menopause (age at onset); LIHC cis rs782590 0.967 rs11125581 chr2:55796527 C/G cg18811423 chr2:55921094 PNPT1 1.01 16.22 0.66 2.71e-44 Metabolic syndrome; LIHC cis rs1059312 0.808 rs2306683 chr12:129299675 C/G cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.77 -16.64 -0.67 5.54e-46 Systemic lupus erythematosus; LIHC cis rs11098499 0.908 rs28499576 chr4:120386677 G/A cg09307838 chr4:120376055 NA 0.78 12.21 0.55 1.08e-28 Corneal astigmatism; LIHC cis rs4819052 0.807 rs7283915 chr21:46671288 T/C cg22633049 chr21:46681294 NA -0.37 -6.48 -0.33 3.21e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs597539 0.652 rs673821 chr11:68678718 G/T cg06028808 chr11:68637592 NA 0.46 6.01 0.31 4.8e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1670533 1.000 rs62879260 chr4:1050850 T/C cg27284194 chr4:1044797 NA 0.6 8.83 0.43 5.59e-17 Recombination rate (females); LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg07092213 chr7:1199455 ZFAND2A -0.46 -6.85 -0.35 3.53e-11 Longevity;Endometriosis; LIHC cis rs7772486 0.905 rs9373486 chr6:146446024 C/G cg23711669 chr6:146136114 FBXO30 -0.63 -10.88 -0.51 7.07e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs17818399 0.547 rs4952833 chr2:46762034 T/C cg02822958 chr2:46747628 ATP6V1E2 0.43 6.33 0.32 7.65e-10 Height; LIHC cis rs34779708 0.966 rs4934737 chr10:35512799 T/C cg03585969 chr10:35415529 CREM 0.87 13.0 0.58 1.08e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7772486 0.719 rs702317 chr6:146005010 C/T cg23711669 chr6:146136114 FBXO30 -0.73 -13.18 -0.58 2.37e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs10865541 0.870 rs6548161 chr2:3424350 A/G cg11642891 chr2:3452563 TTC15 -0.43 -6.83 -0.35 3.97e-11 Obesity-related traits; LIHC trans rs10213084 1.000 rs56221117 chr4:147498316 T/G cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC trans rs1974653 0.781 rs9605062 chr22:20089880 T/C cg20152630 chr19:46405944 MYPOP 0.47 6.05 0.31 3.86e-9 Schizophrenia; LIHC cis rs12594515 1.000 rs12594515 chr15:45985071 C/G cg19682013 chr15:45996608 NA -0.4 -6.88 -0.35 2.94e-11 Waist circumference;Weight; LIHC cis rs17776563 0.919 rs1348005 chr15:89113482 A/G cg05013243 chr15:89149849 MIR1179 0.45 7.61 0.38 2.61e-13 Thyroid hormone levels; LIHC trans rs1814175 0.817 rs7109440 chr11:49966296 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.06 0.36 9.34e-12 Height; LIHC cis rs7818688 0.578 rs11786451 chr8:95897031 T/G cg16049864 chr8:95962084 TP53INP1 0.54 6.12 0.31 2.57e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg06558623 chr16:89946397 TCF25 0.87 13.6 0.59 5.77e-34 Interleukin-17 levels; LIHC cis rs2050392 0.931 rs2265189 chr10:30689316 C/T cg25182066 chr10:30743637 MAP3K8 0.44 7.26 0.37 2.61e-12 Inflammatory bowel disease; LIHC cis rs11871801 0.918 rs34460267 chr17:40615865 T/C cg14558262 chr17:40713999 COASY 0.5 6.83 0.35 3.98e-11 Crohn's disease; LIHC cis rs2153535 0.580 rs9406174 chr6:8516764 T/C cg21535247 chr6:8435926 SLC35B3 0.63 8.22 0.41 4.32e-15 Motion sickness; LIHC cis rs80282103 0.867 rs11819178 chr10:1098417 A/G cg20335179 chr10:1068567 C10orf110;IDI2 -0.57 -6.02 -0.31 4.52e-9 Glomerular filtration rate (creatinine); LIHC cis rs548181 0.611 rs562599 chr11:125459951 A/C cg03464685 chr11:125439445 EI24 1.39 14.51 0.62 1.68e-37 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4407350 0.837 rs4823328 chr22:44908999 C/T cg04154583 chr22:44889756 LDOC1L 0.3 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.758 rs9801444 chr7:1080444 A/C cg04025307 chr7:1156635 C7orf50 -0.56 -8.86 -0.43 4.61e-17 Longevity;Endometriosis; LIHC cis rs6545883 0.929 rs2252662 chr2:61670731 T/C cg14146966 chr2:61757674 XPO1 0.47 8.19 0.4 5.25e-15 Tuberculosis; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg07677032 chr17:61819896 STRADA 0.43 6.36 0.33 6.44e-10 Prudent dietary pattern; LIHC cis rs5769707 0.632 rs135876 chr22:50013573 A/G cg07959070 chr22:50026188 C22orf34 -0.32 -7.87 -0.39 4.63e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs709400 0.663 rs28444993 chr14:103930564 T/C cg26031613 chr14:104095156 KLC1 0.72 9.47 0.46 4.85e-19 Body mass index; LIHC cis rs875971 0.862 rs4236208 chr7:65749078 C/T cg18876405 chr7:65276391 NA -0.35 -6.45 -0.33 3.84e-10 Aortic root size; LIHC cis rs172166 0.694 rs2791332 chr6:28108788 C/T cg23485639 chr6:28045615 ZNF165 0.38 5.97 0.31 6.04e-9 Cardiac Troponin-T levels; LIHC trans rs61931739 0.534 rs11053000 chr12:34079022 C/T cg26384229 chr12:38710491 ALG10B 0.49 6.74 0.34 6.71e-11 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg08219700 chr8:58056026 NA 0.52 7.12 0.36 6.34e-12 Developmental language disorder (linguistic errors); LIHC cis rs55665837 0.701 rs11023272 chr11:14630370 T/C cg19336497 chr11:14380999 RRAS2 -0.37 -6.21 -0.32 1.54e-9 Vitamin D levels; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg11060661 chr22:24314208 DDT;DDTL 0.62 10.62 0.5 5.79e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs826838 0.967 rs2892410 chr12:38990282 A/G cg13010199 chr12:38710504 ALG10B -0.57 -7.08 -0.36 8.29e-12 Heart rate; LIHC cis rs875971 0.825 rs4587224 chr7:65736182 G/A cg18252515 chr7:66147081 NA 0.45 6.37 0.33 6.18e-10 Aortic root size; LIHC cis rs9322817 0.625 rs2499655 chr6:105307435 G/A cg02098413 chr6:105308735 HACE1 0.44 8.32 0.41 2.16e-15 Thyroid stimulating hormone; LIHC cis rs11671005 0.652 rs11545185 chr19:59028585 G/A cg25952890 chr19:58913133 NA 0.64 6.24 0.32 1.3e-9 Mean platelet volume; LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg02951883 chr7:2050386 MAD1L1 -0.85 -15.27 -0.64 1.69e-40 Bipolar disorder and schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01301323 chr12:77252588 CSRP2 0.43 7.14 0.36 5.57e-12 Longevity; LIHC cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg06634786 chr22:41940651 POLR3H 0.73 7.59 0.38 3.16e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2976388 0.609 rs2572908 chr8:143802636 A/G cg06565975 chr8:143823917 SLURP1 0.33 6.14 0.32 2.24e-9 Urinary tract infection frequency; LIHC trans rs2727020 0.523 rs4115783 chr11:49556026 G/A cg03929089 chr4:120376271 NA 0.68 10.06 0.48 4.89e-21 Coronary artery disease; LIHC cis rs11588062 1.000 rs11588062 chr1:46779764 C/T cg24542714 chr1:46669345 POMGNT1;C1orf190 0.44 7.28 0.37 2.33e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7772486 0.902 rs2144476 chr6:146322484 G/A cg23711669 chr6:146136114 FBXO30 0.57 10.01 0.48 7.47e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs16854884 0.657 rs6769910 chr3:143737830 C/G cg06585982 chr3:143692056 C3orf58 0.55 7.17 0.36 4.79e-12 Economic and political preferences (feminism/equality); LIHC cis rs600806 0.778 rs2039694 chr1:109991700 A/G cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.32 -0.32 8.08e-10 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.885 rs28576202 chr21:46674684 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.88 0.39 4.55e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1814175 0.533 rs4528310 chr11:49983106 C/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs13118159 0.872 rs3903127 chr4:1348806 A/C cg16405210 chr4:1374714 KIAA1530 -0.61 -7.73 -0.39 1.18e-13 Longevity; LIHC trans rs7395662 0.591 rs12807777 chr11:48593754 A/T cg15704280 chr7:45808275 SEPT13 -0.47 -7.03 -0.36 1.14e-11 HDL cholesterol; LIHC cis rs9549328 0.837 rs9549618 chr13:113628648 G/A cg08528486 chr13:113648767 MCF2L -0.41 -6.59 -0.34 1.68e-10 Systolic blood pressure; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg11494091 chr17:61959527 GH2 0.45 8.1 0.4 9.53e-15 Prudent dietary pattern; LIHC cis rs8114671 0.562 rs6088622 chr20:33419977 C/A cg07148914 chr20:33460835 GGT7 0.6 8.88 0.43 3.98e-17 Height; LIHC cis rs10791097 0.739 rs12279359 chr11:130730544 G/A cg09137382 chr11:130731461 NA 0.42 6.35 0.32 6.9e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7979473 1 rs7979473 chr12:121420260 A/G cg02403541 chr12:121454288 C12orf43 -0.36 -6.05 -0.31 3.71e-9 C-reactive protein; LIHC cis rs748404 0.660 rs518288 chr15:43763999 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.3 0.37 2.01e-12 Lung cancer; LIHC cis rs2635047 0.967 rs12960444 chr18:44607314 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.55 7.52 0.38 4.75e-13 Educational attainment; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg16989107 chr1:46598393 PIK3R3 0.44 6.36 0.33 6.36e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs13191362 0.938 rs35760705 chr6:163020637 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.61 5.76 0.3 1.87e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7635838 0.859 rs9875414 chr3:11453559 A/G cg00170343 chr3:11313890 ATG7 0.42 6.55 0.33 2.17e-10 HDL cholesterol; LIHC cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.51 -7.16 -0.36 4.98e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs116095464 0.681 rs10060016 chr5:241100 T/C cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.78e-52 Breast cancer; LIHC cis rs2842992 0.714 rs2495278 chr6:160123674 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.73 12.71 0.57 1.38e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs6847067 0.800 rs11097026 chr4:85803607 G/T cg14553853 chr4:85888001 WDFY3;C4orf12 -0.36 -5.84 -0.3 1.18e-8 Oropharynx cancer; LIHC cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg14004847 chr7:1930337 MAD1L1 -0.42 -6.0 -0.31 5.02e-9 Bipolar disorder and schizophrenia; LIHC cis rs9916302 0.610 rs11078902 chr17:37631883 C/G cg00129232 chr17:37814104 STARD3 -0.44 -6.96 -0.35 1.79e-11 Glomerular filtration rate (creatinine); LIHC cis rs751728 1.000 rs747695 chr6:33736672 G/A cg25922239 chr6:33757077 LEMD2 0.45 7.29 0.37 2.11e-12 Crohn's disease; LIHC cis rs2115536 1.000 rs11637477 chr15:80193295 C/T cg00225070 chr15:80189496 MTHFS 0.66 11.1 0.51 1.19e-24 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs5758511 0.680 rs5758651 chr22:42609148 T/C cg20195005 chr22:42527684 CYP2D6 0.31 5.91 0.3 8.33e-9 Birth weight; LIHC cis rs2303759 0.918 rs7251704 chr19:49890873 T/G cg22590775 chr19:49891494 CCDC155 0.48 7.86 0.39 5.08e-14 Multiple sclerosis; LIHC cis rs6964587 0.904 rs2023785 chr7:91547369 C/A cg17063962 chr7:91808500 NA -0.98 -18.41 -0.71 4.45e-53 Breast cancer; LIHC cis rs10089 1.000 rs7703634 chr5:127509223 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.49 6.08 0.31 3.13e-9 Ileal carcinoids; LIHC cis rs7911264 0.628 rs7078243 chr10:94414263 A/C cg25506282 chr10:94462361 NA 0.38 6.37 0.33 6.01e-10 Inflammatory bowel disease; LIHC cis rs7552404 0.824 rs1251079 chr1:76189445 C/T cg22875332 chr1:76189707 ACADM 0.56 12.28 0.55 5.81e-29 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs911119 0.913 rs34792920 chr20:23581876 C/T cg16589663 chr20:23618590 CST3 0.72 7.32 0.37 1.76e-12 Chronic kidney disease; LIHC cis rs7954584 0.520 rs1169096 chr12:122465836 G/C cg21016266 chr12:122356598 WDR66 -0.38 -5.95 -0.31 6.81e-9 Mean corpuscular volume; LIHC cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg25036284 chr2:26402008 FAM59B -0.51 -5.71 -0.3 2.39e-8 Gut microbiome composition (summer); LIHC cis rs61008539 0.815 rs6960062 chr7:884665 A/G cg00475322 chr7:917719 C7orf20 0.47 7.96 0.4 2.6e-14 Perceived unattractiveness to mosquitoes; LIHC cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs796364 0.715 rs1106399 chr2:201003837 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.54 -6.15 -0.32 2.16e-9 Schizophrenia; LIHC trans rs7714584 1.000 rs10463240 chr5:150256853 A/C cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs3806843 0.771 rs2563336 chr5:140107199 A/G cg16179182 chr5:140090404 VTRNA1-1 0.36 5.87 0.3 1.04e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg22105103 chr4:187893119 NA 0.37 9.53 0.46 3.06e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.895 rs2421192 chr2:61643631 T/C cg14146966 chr2:61757674 XPO1 -0.46 -7.91 -0.39 3.7e-14 Tuberculosis; LIHC cis rs2235642 0.685 rs2667681 chr16:1653206 C/T cg03034668 chr16:1723424 CRAMP1L -0.39 -6.82 -0.35 4.09e-11 Coronary artery disease; LIHC cis rs11690935 0.550 rs62183784 chr2:172866696 A/G cg13550731 chr2:172543902 DYNC1I2 0.44 6.83 0.35 4.01e-11 Schizophrenia; LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg06873352 chr17:61820015 STRADA 0.53 7.97 0.4 2.41e-14 Height; LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg09367891 chr1:107599246 PRMT6 0.63 9.73 0.47 6.48e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs597539 0.652 rs686390 chr11:68656077 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.74 10.48 0.49 1.87e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2842992 0.747 rs1547093 chr6:160205991 C/A cg16489826 chr6:160211363 TCP1;MRPL18 0.48 8.43 0.41 9.56e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs11628318 0.614 rs10132160 chr14:103058023 A/G cg12046867 chr14:103022105 NA -0.5 -7.08 -0.36 8.37e-12 Platelet count; LIHC trans rs2243480 1.000 rs13237037 chr7:65997882 T/C cg10756647 chr7:56101905 PSPH 1.02 12.11 0.55 2.53e-28 Diabetic kidney disease; LIHC cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.86 -0.3 1.11e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7098414 0.511 rs12262228 chr10:82160425 C/T cg01528321 chr10:82214614 TSPAN14 0.44 6.67 0.34 1.05e-10 Post bronchodilator FEV1; LIHC cis rs9611565 0.525 rs9611548 chr22:41704143 G/T cg06634786 chr22:41940651 POLR3H -0.6 -6.51 -0.33 2.63e-10 Vitiligo; LIHC cis rs780096 0.546 rs2293571 chr2:27729480 C/T cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.73 -0.3 2.19e-8 Total body bone mineral density; LIHC cis rs12926788 0.546 rs200531 chr16:24756172 G/A cg00152838 chr16:24741724 TNRC6A 0.5 6.16 0.32 2.05e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg07424592 chr7:64974309 NA 0.84 9.64 0.46 1.3e-19 Diabetic kidney disease; LIHC cis rs10876993 0.928 rs813854 chr12:58071347 A/G cg18357645 chr12:58087776 OS9 0.52 8.53 0.42 4.91e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs2404602 0.692 rs66866130 chr15:77128574 T/C cg03037974 chr15:76606532 NA 0.74 14.63 0.62 5.72e-38 Blood metabolite levels; LIHC cis rs6879260 1.000 rs7730585 chr5:179733440 T/C cg23248424 chr5:179741104 GFPT2 -0.41 -6.0 -0.31 5.08e-9 Height; LIHC cis rs58688157 0.705 rs7941547 chr11:611503 G/A cg01842473 chr11:617407 IRF7;MUPCDH -0.57 -6.31 -0.32 8.65e-10 Systemic lupus erythematosus; LIHC trans rs1005277 0.579 rs2505237 chr10:38438898 T/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs4718428 1.000 rs4718428 chr7:66421446 T/G cg18252515 chr7:66147081 NA -0.48 -6.27 -0.32 1.09e-9 Corneal structure; LIHC cis rs7131987 0.903 rs11050153 chr12:29405148 T/C cg14222432 chr12:29376421 FAR2 0.36 7.01 0.35 1.27e-11 QT interval; LIHC cis rs1865760 1.000 rs6910174 chr6:25904414 C/T cg17691542 chr6:26056736 HIST1H1C 0.39 5.91 0.3 8.47e-9 Height; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg27189623 chr16:705930 WDR90 0.36 6.11 0.31 2.74e-9 Height; LIHC cis rs7772486 0.790 rs9376970 chr6:146241472 A/C cg23711669 chr6:146136114 FBXO30 -0.71 -12.73 -0.57 1.17e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs939574 1.000 rs79013471 chr2:220096122 C/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.99 10.6 0.5 7e-23 Platelet distribution width; LIHC cis rs11098499 0.526 rs10026625 chr4:120280136 T/C cg09307838 chr4:120376055 NA 0.51 7.5 0.38 5.51e-13 Corneal astigmatism; LIHC cis rs929354 0.772 rs1002389 chr7:156968323 C/G cg17757837 chr7:157058334 UBE3C 0.73 11.94 0.54 1.05e-27 Body mass index; LIHC cis rs7408868 0.908 rs62113793 chr19:15277336 G/A cg14696996 chr19:15285081 NOTCH3 0.54 7.09 0.36 7.55e-12 Pulse pressure; LIHC cis rs250677 0.652 rs168751 chr5:148438264 C/T cg12140854 chr5:148520817 ABLIM3 -0.53 -5.9 -0.3 8.73e-9 Breast cancer; LIHC cis rs1552244 0.882 rs34779351 chr3:10021801 A/G cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs34330 0.562 rs12229100 chr12:12865836 A/G cg09462578 chr12:12878428 APOLD1 0.78 10.39 0.49 3.62e-22 Systemic lupus erythematosus; LIHC cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.67e-21 Intelligence (multi-trait analysis); LIHC cis rs9818758 0.607 rs67831908 chr3:49313513 T/G cg07636037 chr3:49044803 WDR6 -0.82 -8.32 -0.41 2.09e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs8062405 0.722 rs3785354 chr16:28550667 C/T cg07382826 chr16:28625726 SULT1A1 0.49 7.67 0.38 1.83e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1506636 0.962 rs1472808 chr7:123354536 A/G cg03229431 chr7:123269106 ASB15 -0.59 -11.97 -0.54 8.22e-28 Plateletcrit;Platelet count; LIHC cis rs9914988 0.832 rs35033748 chr17:27179590 T/C cg20469991 chr17:27169893 C17orf63 -0.54 -6.42 -0.33 4.57e-10 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6545883 0.929 rs778154 chr2:61646631 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.47 -0.37 6.59e-13 Tuberculosis; LIHC cis rs4423214 0.959 rs11606033 chr11:71154204 A/G cg24826892 chr11:71159390 DHCR7 0.52 6.85 0.35 3.52e-11 Vitamin D levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08276543 chr12:124856791 NCOR2 0.46 6.86 0.35 3.14e-11 Longevity; LIHC cis rs4631830 1.000 rs4631830 chr10:51543344 C/T cg20129853 chr10:51489980 NA -0.4 -8.57 -0.42 3.62e-16 Prostate-specific antigen levels; LIHC cis rs10883723 0.810 rs1884929 chr10:104275418 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6964587 0.692 rs4727268 chr7:91840724 T/C cg17063962 chr7:91808500 NA 0.68 12.19 0.55 1.24e-28 Breast cancer; LIHC cis rs35110281 0.641 rs9983670 chr21:45083425 A/G cg01579765 chr21:45077557 HSF2BP -0.34 -6.25 -0.32 1.25e-9 Mean corpuscular volume; LIHC cis rs79149102 0.579 rs6495142 chr15:75320166 C/T cg09165964 chr15:75287851 SCAMP5 -0.61 -8.18 -0.4 5.65e-15 Lung cancer; LIHC cis rs208520 0.690 rs10455194 chr6:66743356 A/G cg07460842 chr6:66804631 NA 0.78 9.07 0.44 9.76e-18 Exhaled nitric oxide output; LIHC cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.98 9.62 0.46 1.49e-19 Platelet count; LIHC cis rs7937682 0.881 rs4936678 chr11:111625085 C/T cg09085632 chr11:111637200 PPP2R1B 1.15 11.65 0.53 1.23e-26 Primary sclerosing cholangitis; LIHC cis rs6831352 0.918 rs28987097 chr4:100049579 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs10504073 0.605 rs62507176 chr8:49930321 G/A cg00325661 chr8:49890786 NA 0.39 9.53 0.46 2.97e-19 Blood metabolite ratios; LIHC cis rs11792861 0.591 rs11791855 chr9:111684139 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 10.62 0.5 5.94e-23 Menarche (age at onset); LIHC cis rs4409675 0.576 rs11247705 chr1:28212272 G/A cg23691781 chr1:28212827 C1orf38 0.31 7.39 0.37 1.13e-12 Corneal astigmatism; LIHC trans rs561341 0.700 rs886223 chr17:30229877 G/T cg20587970 chr11:113659929 NA -0.5 -6.34 -0.32 7.45e-10 Hip circumference adjusted for BMI; LIHC cis rs2191566 0.664 rs6509138 chr19:44570393 C/A cg20607764 chr19:44506953 ZNF230 -0.37 -6.23 -0.32 1.36e-9 Acute lymphoblastic leukemia (childhood); LIHC trans rs8002861 0.935 rs1373903 chr13:44475514 G/T cg17145862 chr1:211918768 LPGAT1 0.67 13.37 0.59 4.2e-33 Leprosy; LIHC cis rs6448317 1.000 rs11934149 chr4:24938953 T/C cg21108841 chr4:24914750 CCDC149 -0.47 -6.0 -0.31 5e-9 Heschl's gyrus morphology; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17635903 chr4:4871426 NA 0.44 6.29 0.32 9.83e-10 Lung function (FEV1/FVC); LIHC cis rs57502260 0.834 rs3736228 chr11:68201295 A/G cg16797656 chr11:68205561 LRP5 -0.57 -7.64 -0.38 2.19e-13 Total body bone mineral density (age 45-60); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17782706 chr4:184580436 C4orf41;RWDD4A 0.43 6.21 0.32 1.55e-9 Pancreatic cancer; LIHC cis rs1552244 0.554 rs6786636 chr3:10045703 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.76 0.39 1.01e-13 Alzheimer's disease; LIHC cis rs7095607 0.606 rs7100561 chr10:69958472 G/A cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.66e-9 Lung function (FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13704629 chr14:73396469 DCAF4 0.39 6.06 0.31 3.58e-9 Pancreatic cancer; LIHC cis rs2070488 1.000 rs762317 chr3:38497659 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15572692 chr19:14016919 C19orf57;CC2D1A -0.45 -6.09 -0.31 2.96e-9 Systolic blood pressure; LIHC cis rs72781680 0.593 rs72797817 chr2:24350569 A/G cg06627628 chr2:24431161 ITSN2 -0.62 -7.33 -0.37 1.64e-12 Lymphocyte counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05313302 chr10:75006908 DNAJC9 -0.4 -6.31 -0.32 8.71e-10 Pancreatic cancer; LIHC cis rs700651 0.821 rs700663 chr2:198670478 T/A cg03934865 chr2:198174659 NA 0.46 6.58 0.34 1.74e-10 Intracranial aneurysm; LIHC cis rs4819052 0.704 rs2297283 chr21:46683590 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.6 8.87 0.43 4.17e-17 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg22887498 chr19:39401301 NA 0.42 6.22 0.32 1.46e-9 Immature fraction of reticulocytes; LIHC cis rs6723226 0.598 rs2710629 chr2:32765844 C/T cg02381751 chr2:32503542 YIPF4 0.46 6.71 0.34 8.19e-11 Intelligence (multi-trait analysis); LIHC cis rs4478858 0.735 rs12563669 chr1:31858067 A/G cg00250761 chr1:31883323 NA -0.28 -6.72 -0.34 7.85e-11 Alcohol dependence; LIHC cis rs763121 0.853 rs5757166 chr22:38995385 G/T cg21395723 chr22:39101663 GTPBP1 0.41 6.88 0.35 2.8e-11 Menopause (age at onset); LIHC cis rs7927771 0.826 rs2293578 chr11:47437403 C/T cg20135002 chr11:47629003 NA -0.58 -9.79 -0.47 4.23e-20 Subjective well-being; LIHC cis rs2274273 0.719 rs17740551 chr14:55751325 C/T cg01864836 chr14:55583639 NA -0.36 -5.9 -0.3 8.84e-9 Protein biomarker; LIHC cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -5.9 -0.3 8.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2731664 0.792 rs466256 chr5:176875956 C/A cg23176889 chr5:176863531 GRK6 -0.72 -12.45 -0.56 1.37e-29 Intelligence (multi-trait analysis); LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg01516881 chr6:292596 DUSP22 -0.52 -6.65 -0.34 1.15e-10 Menopause (age at onset); LIHC cis rs4843747 0.671 rs28671027 chr16:88116323 G/A cg06050784 chr16:88016603 BANP 0.34 6.18 0.32 1.78e-9 Menopause (age at onset); LIHC cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg00166722 chr3:10149974 C3orf24 0.48 5.75 0.3 2.01e-8 Alzheimer's disease; LIHC cis rs9420 0.961 rs11602109 chr11:57435296 G/A cg19752551 chr11:57585705 CTNND1 -0.53 -7.4 -0.37 1.07e-12 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20831041 chr11:464554 PTDSS2 0.45 6.84 0.35 3.77e-11 Longevity; LIHC cis rs7312933 0.670 rs10880258 chr12:42547531 C/T cg17420585 chr12:42539391 GXYLT1 -0.37 -5.86 -0.3 1.11e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs6912958 0.712 rs7772561 chr6:88331299 A/G cg23605328 chr1:201951606 RNPEP 0.39 6.18 0.32 1.86e-9 Monocyte percentage of white cells; LIHC cis rs1018836 0.632 rs9642910 chr8:91475724 G/T cg16814680 chr8:91681699 NA -0.37 -6.04 -0.31 4.1e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs74544699 1.000 rs57274239 chr4:74789027 A/G cg16072462 chr4:74847758 PF4 0.59 6.03 0.31 4.32e-9 Growth-regulated protein alpha levels; LIHC trans rs8073060 0.671 rs9894813 chr17:33873848 C/T cg19694781 chr19:47549865 TMEM160 0.96 9.93 0.47 1.44e-20 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg06873352 chr17:61820015 STRADA 0.71 12.16 0.55 1.68e-28 Prudent dietary pattern; LIHC cis rs2075165 0.901 rs759329 chr1:156230936 A/G cg07234388 chr1:156261841 TMEM79 0.5 8.8 0.43 6.86e-17 Tonsillectomy; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.28 0.55 5.92e-29 Prudent dietary pattern; LIHC cis rs2549003 1.000 rs10068129 chr5:131821246 A/G cg21138405 chr5:131827807 IRF1 -0.36 -9.31 -0.45 1.59e-18 Asthma (sex interaction); LIHC cis rs1190552 0.706 rs10135045 chr14:102872469 T/G cg10241871 chr14:102965420 TECPR2 0.39 5.94 0.31 6.98e-9 Blood protein levels; LIHC cis rs4974559 0.501 rs1250096 chr4:1238836 G/C cg02980000 chr4:1222292 CTBP1 -0.86 -6.54 -0.33 2.21e-10 Systolic blood pressure; LIHC cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg21970626 chr13:21893289 NA -0.37 -6.11 -0.31 2.76e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs911119 0.913 rs2405392 chr20:23569186 C/T cg16589663 chr20:23618590 CST3 0.65 6.74 0.34 6.57e-11 Chronic kidney disease; LIHC cis rs11190604 1.000 rs75063298 chr10:102213600 C/A cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg08392591 chr16:89556376 ANKRD11 0.56 8.66 0.42 1.87e-16 Multiple myeloma (IgH translocation); LIHC cis rs1030268 0.859 rs10954428 chr7:133388056 C/T cg03336402 chr7:133662267 EXOC4 -0.48 -6.76 -0.34 5.97e-11 Intelligence (multi-trait analysis); LIHC trans rs2243480 1.000 rs427044 chr7:65508545 G/A cg10756647 chr7:56101905 PSPH 1.08 13.59 0.59 6.08e-34 Diabetic kidney disease; LIHC cis rs4555082 1.000 rs7146012 chr14:105757566 G/A cg06808227 chr14:105710500 BRF1 -0.5 -6.59 -0.34 1.69e-10 Mean platelet volume;Platelet distribution width; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg12096988 chr19:57702809 ZNF264 -0.59 -6.83 -0.35 3.98e-11 Systolic blood pressure; LIHC cis rs769267 0.930 rs892022 chr19:19613381 G/A cg03709012 chr19:19516395 GATAD2A 1.01 18.14 0.7 5.53e-52 Tonsillectomy; LIHC cis rs2455799 0.613 rs2470542 chr3:15724133 A/C cg12698662 chr3:15914712 MIR563 -0.37 -6.82 -0.35 4.07e-11 Mean platelet volume; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg21747090 chr2:27597821 SNX17 -0.44 -6.55 -0.33 2.17e-10 Total body bone mineral density; LIHC cis rs593982 0.858 rs480989 chr11:65493992 A/G cg08755490 chr11:65554678 OVOL1 0.5 6.6 0.34 1.53e-10 Atopic dermatitis; LIHC cis rs9916302 0.904 rs587343 chr17:37440603 C/T cg03013999 chr17:37608204 MED1 -0.34 -5.79 -0.3 1.58e-8 Glomerular filtration rate (creatinine); LIHC cis rs11711311 0.955 rs9830102 chr3:113408302 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.34 -5.88 -0.3 9.83e-9 IgG glycosylation; LIHC cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg06634786 chr22:41940651 POLR3H 0.72 7.49 0.38 5.76e-13 Vitiligo; LIHC trans rs9929218 0.551 rs4783663 chr16:68720271 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.93 22.27 0.77 1.53e-68 Colorectal cancer; LIHC cis rs6076065 0.748 rs2236023 chr20:23373043 A/C cg11657817 chr20:23433608 CST11 0.32 6.82 0.35 4.09e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg24209194 chr3:40518798 ZNF619 0.65 9.97 0.47 1.02e-20 Renal cell carcinoma; LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC cis rs12594515 1.000 rs11854554 chr15:45994546 C/G cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg04267008 chr7:1944627 MAD1L1 -0.63 -10.01 -0.48 7.15e-21 Bipolar disorder and schizophrenia; LIHC cis rs6499255 0.904 rs74029403 chr16:69710472 A/C cg15192750 chr16:69999425 NA 0.46 6.06 0.31 3.63e-9 IgE levels; LIHC cis rs965469 0.843 rs6037580 chr20:3351374 A/G cg25506879 chr20:3388711 C20orf194 -0.54 -6.52 -0.33 2.58e-10 IFN-related cytopenia; LIHC cis rs758324 0.947 rs13170693 chr5:131187826 T/C cg06307176 chr5:131281290 NA 0.4 5.74 0.3 2.12e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7249142 0.562 rs12980955 chr19:19283646 T/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.44 -7.26 -0.37 2.63e-12 IgG glycosylation; LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg14780466 chr2:20870812 GDF7 -0.43 -8.92 -0.43 2.97e-17 Abdominal aortic aneurysm; LIHC cis rs7568458 0.684 rs7579147 chr2:85805654 G/A cg02493740 chr2:85810744 VAMP5 -0.46 -7.46 -0.37 7.37e-13 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7659604 0.540 rs11734075 chr4:122695685 C/T cg19671926 chr4:122722719 EXOSC9 0.56 8.66 0.42 1.93e-16 Type 2 diabetes; LIHC cis rs2019216 1.000 rs2019216 chr17:21909650 C/T cg22648282 chr17:21454238 C17orf51 -0.35 -6.09 -0.31 3.01e-9 Pelvic organ prolapse; LIHC cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg01788221 chr16:89496183 ANKRD11 -0.39 -6.33 -0.32 7.54e-10 Multiple myeloma (IgH translocation); LIHC cis rs11098699 0.821 rs931708 chr4:124202363 G/A cg09941581 chr4:124220074 SPATA5 0.32 6.29 0.32 9.59e-10 Mosquito bite size; LIHC cis rs9522267 0.535 rs914031 chr13:112240176 C/A cg10483660 chr13:112241077 NA -0.22 -5.99 -0.31 5.4e-9 Hepatitis; LIHC cis rs11971779 0.715 rs10954646 chr7:139061069 C/G cg07862535 chr7:139043722 LUC7L2 -0.61 -10.83 -0.51 1.06e-23 Diisocyanate-induced asthma; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg02782426 chr3:40428986 ENTPD3 -0.32 -6.1 -0.31 2.81e-9 Renal cell carcinoma; LIHC cis rs56104184 0.779 rs2131093 chr19:49350693 A/T cg15549821 chr19:49342101 PLEKHA4 -0.99 -9.4 -0.45 8.24e-19 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs796364 1.000 rs281785 chr2:200749566 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.79 9.16 0.44 4.85e-18 Schizophrenia; LIHC cis rs2842992 0.915 rs2758335 chr6:160111011 G/A cg26839252 chr6:160211577 TCP1;MRPL18 0.36 6.06 0.31 3.58e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs7309 0.935 rs10930013 chr2:162070325 G/A cg21518248 chr2:162101506 NA 0.46 7.09 0.36 7.91e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs10916814 0.632 rs4655224 chr1:20902195 A/C cg24502330 chr1:20914028 CDA -0.31 -6.79 -0.34 4.83e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg18538332 chr22:24372958 LOC391322 -0.66 -9.78 -0.47 4.43e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs250677 0.687 rs250673 chr5:148445798 C/T cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC cis rs11229555 0.645 rs12269745 chr11:58176875 G/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9399135 0.967 rs6908512 chr6:135367757 A/G cg22676075 chr6:135203613 NA 0.4 6.36 0.33 6.58e-10 Red blood cell count; LIHC cis rs10876993 1.000 rs10876993 chr12:58062667 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.42 -0.33 4.46e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs1707322 0.964 rs12067716 chr1:46434428 T/A cg03146154 chr1:46216737 IPP 0.47 7.59 0.38 2.97e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg11243680 chr12:31881778 AMN1 -0.58 -6.83 -0.35 3.92e-11 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04313349 chr17:76778764 CYTH1 0.45 6.19 0.32 1.69e-9 Lung function (FEV1/FVC); LIHC cis rs8062405 0.965 rs62037363 chr16:28865042 T/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs1814175 0.817 rs4084376 chr11:49831160 T/C cg03929089 chr4:120376271 NA -0.9 -18.4 -0.71 4.84e-53 Height; LIHC cis rs9394841 0.667 rs3747750 chr6:41760372 C/G cg08135965 chr6:41755394 TOMM6 0.44 5.72 0.3 2.34e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs8044995 0.563 rs2279540 chr16:68395061 T/C cg09835421 chr16:68378352 PRMT7 -0.82 -9.6 -0.46 1.8e-19 Schizophrenia; LIHC cis rs10504073 0.626 rs6472220 chr8:50008477 C/A cg00325661 chr8:49890786 NA 0.31 7.1 0.36 7.42e-12 Blood metabolite ratios; LIHC cis rs7772486 0.875 rs6930975 chr6:146387111 C/T cg23711669 chr6:146136114 FBXO30 0.58 10.18 0.48 1.89e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs61440199 1.000 rs73818811 chr3:20144715 G/A cg00235661 chr3:20228976 SGOL1 -0.41 -5.84 -0.3 1.23e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25613101 chr22:38577875 PLA2G6 0.51 6.75 0.34 6.31e-11 Lung function (FEV1/FVC); LIHC cis rs965469 0.779 rs6515791 chr20:3310443 C/G cg25506879 chr20:3388711 C20orf194 -0.5 -6.14 -0.32 2.28e-9 IFN-related cytopenia; LIHC cis rs7772486 0.701 rs2244308 chr6:146213706 C/T cg05347473 chr6:146136440 FBXO30 0.35 5.72 0.3 2.29e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs965469 0.652 rs4507156 chr20:3228460 A/G cg25506879 chr20:3388711 C20orf194 0.56 7.69 0.38 1.6e-13 IFN-related cytopenia; LIHC cis rs1577917 0.958 rs2121594 chr6:86576854 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -11.18 -0.52 6.27e-25 Response to antipsychotic treatment; LIHC cis rs11212260 0.655 rs11212221 chr11:107293365 T/C cg25435332 chr11:107328525 CWF19L2 0.79 8.09 0.4 1.08e-14 IgG glycosylation; LIHC cis rs5769707 0.967 rs9616701 chr22:50025546 G/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.6 -0.42 2.82e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs919433 0.680 rs1563340 chr2:198414713 A/T cg03934865 chr2:198174659 NA 0.54 8.25 0.41 3.45e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8016982 0.662 rs7144005 chr14:81656437 C/T cg01989461 chr14:81687754 GTF2A1 0.53 9.25 0.45 2.59e-18 Schizophrenia; LIHC cis rs5769707 0.605 rs6009791 chr22:50025265 T/C cg07959070 chr22:50026188 C22orf34 -0.34 -8.36 -0.41 1.59e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs3096299 0.967 rs28575874 chr16:89469890 C/T cg02187348 chr16:89574699 SPG7 0.52 7.7 0.38 1.43e-13 Multiple myeloma (IgH translocation); LIHC cis rs644799 0.526 rs693172 chr11:95636618 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.6 9.41 0.45 7.7e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9325144 0.505 rs6582691 chr12:38806894 T/C cg13010199 chr12:38710504 ALG10B -0.43 -6.75 -0.34 6.27e-11 Morning vs. evening chronotype; LIHC cis rs3096299 0.566 rs4129126 chr16:89561475 A/C cg02187348 chr16:89574699 SPG7 0.47 6.42 0.33 4.45e-10 Multiple myeloma (IgH translocation); LIHC trans rs10213084 1.000 rs10212914 chr4:147499085 T/C cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs8114671 0.562 rs2064454 chr20:33496169 C/T cg07148914 chr20:33460835 GGT7 0.65 9.77 0.47 4.95e-20 Height; LIHC cis rs8058578 0.945 rs34480360 chr16:30798689 G/A cg02466173 chr16:30829666 NA -0.43 -6.66 -0.34 1.11e-10 Multiple myeloma; LIHC cis rs2404602 0.684 rs11072602 chr15:76873467 T/C cg03037974 chr15:76606532 NA -0.61 -10.21 -0.48 1.55e-21 Blood metabolite levels; LIHC cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg08888203 chr3:10149979 C3orf24 0.63 7.04 0.36 1.03e-11 Alzheimer's disease; LIHC cis rs35883536 1.000 rs4243810 chr1:101139914 T/C cg14515779 chr1:101123966 NA -0.67 -13.3 -0.58 8.12e-33 Monocyte count; LIHC cis rs921968 0.548 rs13427522 chr2:219438359 C/T cg18887096 chr2:219472410 PLCD4 0.35 6.22 0.32 1.49e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg03721293 chr16:90014378 DEF8 0.42 7.06 0.36 9.13e-12 Skin colour saturation; LIHC cis rs986417 0.636 rs8020587 chr14:60952612 A/G cg27398547 chr14:60952738 C14orf39 0.83 9.68 0.46 9.59e-20 Gut microbiota (bacterial taxa); LIHC cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg03517284 chr6:25882590 NA 0.49 6.12 0.31 2.61e-9 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.692 rs1471780 chr15:77026526 T/C cg03037974 chr15:76606532 NA 0.74 14.67 0.62 3.89e-38 Blood metabolite levels; LIHC cis rs34172651 0.545 rs8056132 chr16:24716348 A/G cg00339695 chr16:24857497 SLC5A11 0.37 6.12 0.31 2.62e-9 Intelligence (multi-trait analysis); LIHC cis rs2257205 0.667 rs9893027 chr17:56653448 G/C cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg06212747 chr3:49208901 KLHDC8B 0.65 8.89 0.43 3.61e-17 Menarche (age at onset); LIHC trans rs916888 0.821 rs199525 chr17:44847834 T/G cg26692224 chr17:62915920 LRRC37A3 -0.68 -6.29 -0.32 9.66e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs3780486 0.505 rs1411609 chr9:33137303 C/T cg20290983 chr6:43655470 MRPS18A 0.96 20.09 0.74 7.44e-60 IgG glycosylation; LIHC cis rs35110281 0.511 rs2298562 chr21:45085236 A/G cg21573476 chr21:45109991 RRP1B -0.58 -10.98 -0.51 3.14e-24 Mean corpuscular volume; LIHC cis rs9733 0.596 rs17658705 chr1:150678071 A/C cg17724175 chr1:150552817 MCL1 -0.5 -9.96 -0.47 1.1e-20 Tonsillectomy; LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg14159672 chr1:205819179 PM20D1 0.69 9.72 0.47 7.18e-20 Menarche (age at onset); LIHC cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg23978390 chr7:1156363 C7orf50 0.55 8.18 0.4 5.76e-15 Longevity;Endometriosis; LIHC cis rs13343954 0.518 rs2216594 chr19:33533258 G/A cg27124370 chr19:33622961 WDR88 0.52 7.74 0.39 1.13e-13 Colorectal cancer; LIHC cis rs6088580 0.634 rs4911153 chr20:32961547 C/T cg08999081 chr20:33150536 PIGU -0.66 -13.16 -0.58 2.78e-32 Glomerular filtration rate (creatinine); LIHC cis rs2153535 0.580 rs9505458 chr6:8479215 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs6424115 0.708 rs12755062 chr1:24185025 T/A cg08896387 chr1:24191740 FUCA1 0.39 6.15 0.32 2.18e-9 Immature fraction of reticulocytes; LIHC cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.72 12.48 0.56 1.05e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs600806 0.888 rs652651 chr1:109844532 A/G cg08911820 chr1:110026001 ATXN7L2 -0.57 -6.67 -0.34 1e-10 Intelligence (multi-trait analysis); LIHC cis rs477895 0.938 rs28395875 chr11:64024048 G/C cg04317338 chr11:64019027 PLCB3 0.86 8.61 0.42 2.73e-16 Mean platelet volume; LIHC cis rs10463316 0.862 rs7700650 chr5:150776473 C/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.71 -0.34 7.92e-11 Metabolite levels (Pyroglutamine); LIHC cis rs3020736 0.500 rs2839708 chr22:42500745 A/G cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg17414733 chr19:21688647 ZNF429 -0.43 -6.63 -0.34 1.28e-10 Bilirubin levels; LIHC cis rs6456156 0.586 rs7761977 chr6:167485678 A/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.51 -0.42 5.66e-16 Primary biliary cholangitis; LIHC cis rs57502260 0.679 rs72936524 chr11:68275898 G/A cg20283391 chr11:68216788 NA -0.51 -6.14 -0.32 2.3e-9 Total body bone mineral density (age 45-60); LIHC cis rs7944584 0.563 rs61895112 chr11:47560433 T/C cg20307385 chr11:47447363 PSMC3 0.89 12.47 0.56 1.12e-29 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs311392 0.902 rs413667 chr8:55091908 C/A cg11783602 chr8:55087084 NA -0.31 -6.09 -0.31 3.02e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs11673344 0.864 rs1879497 chr19:37632877 G/T cg27390819 chr19:37464633 NA -0.51 -6.16 -0.32 2.05e-9 Obesity-related traits; LIHC cis rs2637266 0.935 rs2579719 chr10:78400026 A/G cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg26874164 chr19:58962979 ZNF324B 0.59 9.16 0.44 4.84e-18 Uric acid clearance; LIHC cis rs7727544 0.735 rs272867 chr5:131681057 G/A cg07395648 chr5:131743802 NA -0.3 -6.22 -0.32 1.44e-9 Blood metabolite levels; LIHC cis rs8177253 0.965 rs8177245 chr3:133479230 A/G cg12373951 chr3:133503437 NA 0.7 12.49 0.56 9.26e-30 Iron status biomarkers; LIHC cis rs796364 0.950 rs188146 chr2:200750444 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.72 8.41 0.41 1.1e-15 Schizophrenia; LIHC cis rs1348850 0.597 rs4893964 chr2:178447658 G/T cg27490568 chr2:178487706 NA 0.8 10.09 0.48 4.11e-21 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1055129 0.560 rs56248937 chr17:73915153 T/A cg10935138 chr17:73851978 WBP2 0.48 7.21 0.36 3.72e-12 White matter hyperintensity burden; LIHC cis rs7923452 0.507 rs612802 chr10:30756441 G/A cg25182066 chr10:30743637 MAP3K8 -0.68 -11.09 -0.51 1.25e-24 Itch intensity from mosquito bite; LIHC cis rs7188697 0.922 rs37057 chr16:58561954 T/C cg02549819 chr16:58548995 SETD6 -0.45 -7.2 -0.36 3.85e-12 QT interval; LIHC cis rs7208859 0.673 rs73277978 chr17:29191449 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1945213 0.694 rs34537090 chr11:55843285 G/C cg15704280 chr7:45808275 SEPT13 0.6 7.77 0.39 9.45e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg18538332 chr22:24372958 LOC391322 -0.56 -7.95 -0.39 2.75e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2851682 0.611 rs2072114 chr11:61605215 A/G cg27386326 chr11:61587980 NA 0.57 9.2 0.45 3.72e-18 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs10423674 0.526 rs2023878 chr19:18834124 A/G cg14292368 chr19:18793705 CRTC1 0.41 5.74 0.3 2.14e-8 Menarche (age at onset); LIHC cis rs10540 1.000 rs61876334 chr11:487201 T/C cg03352830 chr11:487213 PTDSS2 0.69 6.02 0.31 4.6e-9 Body mass index; LIHC cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs9916302 0.904 rs4357971 chr17:37717280 C/T cg03013999 chr17:37608204 MED1 0.34 5.73 0.3 2.21e-8 Glomerular filtration rate (creatinine); LIHC cis rs12478296 1.000 rs55732177 chr2:243040006 C/T cg18898632 chr2:242989856 NA -0.58 -7.84 -0.39 5.85e-14 Obesity-related traits; LIHC cis rs7659604 1.000 rs28532673 chr4:122664323 A/G cg19748678 chr4:122722346 EXOSC9 -0.37 -6.45 -0.33 3.89e-10 Type 2 diabetes; LIHC cis rs36051895 0.575 rs7035251 chr9:5133665 T/A cg02405213 chr9:5042618 JAK2 -0.68 -11.68 -0.53 9.05e-27 Pediatric autoimmune diseases; LIHC cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg05590025 chr7:65112418 INTS4L2 -0.57 -6.35 -0.32 7.03e-10 Diabetic kidney disease; LIHC cis rs2180341 0.961 rs7774468 chr6:127592501 G/C cg24812749 chr6:127587940 RNF146 1.06 15.77 0.65 1.75e-42 Breast cancer; LIHC cis rs10504229 0.773 rs60466370 chr8:58171248 A/C cg20607798 chr8:58055168 NA 0.46 5.81 0.3 1.44e-8 Developmental language disorder (linguistic errors); LIHC cis rs17376456 0.825 rs10476590 chr5:93244884 A/T cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg19318889 chr4:1322082 MAEA 0.63 10.21 0.48 1.54e-21 Longevity; LIHC trans rs3780486 0.846 rs7850878 chr9:33126570 A/G cg20290983 chr6:43655470 MRPS18A 1.18 31.11 0.86 9.11e-102 IgG glycosylation; LIHC cis rs16866061 0.517 rs7580488 chr2:225473263 C/T cg12698349 chr2:225449008 CUL3 0.41 6.39 0.33 5.4e-10 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs311392 0.902 rs411371 chr8:55092609 G/A cg20636351 chr8:55087400 NA -0.38 -7.73 -0.39 1.2e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs6840360 1.000 rs7671651 chr4:152597202 C/G cg22705602 chr4:152727874 NA -0.29 -6.31 -0.32 8.61e-10 Intelligence (multi-trait analysis); LIHC cis rs7296418 0.961 rs4148863 chr12:123569375 A/G cg05973401 chr12:123451056 ABCB9 0.51 8.05 0.4 1.37e-14 Platelet count; LIHC cis rs1348850 0.645 rs7571386 chr2:178442687 A/C cg27490568 chr2:178487706 NA 0.76 9.51 0.46 3.47e-19 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2303759 0.918 rs9749416 chr19:49885005 G/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.93 0.43 2.71e-17 Multiple sclerosis; LIHC cis rs2075371 0.966 rs1619682 chr7:133996703 T/G cg11752832 chr7:134001865 SLC35B4 0.52 7.63 0.38 2.29e-13 Mean platelet volume; LIHC trans rs61931739 0.534 rs10844729 chr12:34022919 A/G cg26384229 chr12:38710491 ALG10B 0.51 7.17 0.36 4.71e-12 Morning vs. evening chronotype; LIHC cis rs9399135 0.967 rs9321481 chr6:135352648 C/G cg24558204 chr6:135376177 HBS1L -0.36 -5.74 -0.3 2.12e-8 Red blood cell count; LIHC cis rs6582630 0.519 rs11514056 chr12:38284001 G/T cg13010199 chr12:38710504 ALG10B 0.47 5.72 0.3 2.31e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs7224685 0.506 rs12452569 chr17:4023667 T/A cg09695851 chr17:3907499 NA 0.62 7.19 0.36 3.98e-12 Type 2 diabetes; LIHC cis rs61041384 0.661 rs74240771 chr12:123696963 G/A cg00376283 chr12:123451042 ABCB9 -0.54 -5.89 -0.3 9.12e-9 Schizophrenia; LIHC cis rs1046896 0.519 rs9900369 chr17:80829807 G/A cg19500275 chr17:80737654 TBCD 0.41 5.76 0.3 1.86e-8 Glycated hemoglobin levels; LIHC cis rs875971 0.545 rs10261710 chr7:65714189 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.39 7.73 0.39 1.18e-13 Aortic root size; LIHC trans rs1484948 0.567 rs1567941 chr11:41947842 G/A cg09339301 chr6:163836245 QKI 0.56 6.18 0.32 1.79e-9 RR interval (heart rate); LIHC cis rs2153535 0.580 rs6597325 chr6:8461053 A/C cg21535247 chr6:8435926 SLC35B3 0.63 8.26 0.41 3.22e-15 Motion sickness; LIHC cis rs1865760 0.532 rs2006736 chr6:26086017 C/T cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC cis rs12586317 0.534 rs1568200 chr14:35419592 C/T cg16230307 chr14:35515116 FAM177A1 0.66 10.76 0.5 1.94e-23 Psoriasis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18465072 chr17:30327605 SUZ12 0.3 6.08 0.31 3.21e-9 Cognitive function; LIHC cis rs7552404 1.000 rs7533888 chr1:76160449 A/C cg03433033 chr1:76189801 ACADM 0.66 9.39 0.45 8.81e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs73001065 0.551 rs56397647 chr19:19642795 C/T cg03709012 chr19:19516395 GATAD2A 0.87 9.08 0.44 9.09e-18 LDL cholesterol; LIHC cis rs1997103 1.000 rs6593238 chr7:55411048 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs904251 0.561 rs1757189 chr6:37483727 G/C cg08126542 chr6:37504118 NA -0.37 -6.27 -0.32 1.09e-9 Cognitive performance; LIHC cis rs754466 1.000 rs12220311 chr10:79681507 C/T cg17075019 chr10:79541650 NA -0.63 -8.49 -0.42 6.43e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg12310025 chr6:25882481 NA -0.6 -8.59 -0.42 3.21e-16 Blood metabolite levels; LIHC cis rs7771547 0.573 rs584418 chr6:36395437 G/A cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Platelet distribution width; LIHC trans rs9302065 0.565 rs2993584 chr13:95961678 C/A cg19955956 chr7:72299837 SBDSP;TYW1B 0.36 6.64 0.34 1.27e-10 Blood metabolite levels; LIHC cis rs7715806 0.500 rs2307112 chr5:75003413 A/C cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg10862848 chr6:42927986 GNMT -0.29 -6.56 -0.33 2.03e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs55665837 0.701 rs11023272 chr11:14630370 T/C cg25251204 chr11:14927456 NA 0.43 5.98 0.31 5.71e-9 Vitamin D levels; LIHC cis rs8067354 0.645 rs2102507 chr17:57875907 A/G cg13753209 chr17:57696993 CLTC 0.72 11.42 0.53 8.26e-26 Hemoglobin concentration; LIHC cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg18306943 chr3:40428807 ENTPD3 0.33 5.74 0.3 2.14e-8 Renal cell carcinoma; LIHC cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg18225595 chr11:63971243 STIP1 0.68 8.5 0.42 5.96e-16 Mean platelet volume; LIHC cis rs546131 0.928 rs550313 chr11:34830919 C/T cg06937548 chr11:34938143 PDHX;APIP 0.6 7.86 0.39 4.91e-14 Lung disease severity in cystic fibrosis; LIHC cis rs10197940 0.901 rs2290367 chr2:152266731 T/A cg06191203 chr2:152266755 RIF1 -0.52 -10.11 -0.48 3.35e-21 Lung cancer; LIHC cis rs10461617 0.541 rs860581 chr5:56150537 A/G cg12311346 chr5:56204834 C5orf35 -0.56 -6.14 -0.32 2.32e-9 Type 2 diabetes; LIHC cis rs6570726 0.811 rs375873 chr6:145812371 G/T cg23711669 chr6:146136114 FBXO30 0.5 8.67 0.42 1.72e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs3204270 0.714 rs79243595 chr17:79681220 T/C cg18367735 chr17:79674897 NA 0.72 7.88 0.39 4.32e-14 Dental caries; LIHC cis rs2112347 0.502 rs34342 chr5:74934213 A/C cg00601450 chr5:74908170 NA -0.68 -9.22 -0.45 3.22e-18 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs9814567 1.000 rs2056604 chr3:134312648 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.0 -0.54 6.29e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9308433 0.529 rs10465697 chr1:214499948 T/C cg06198575 chr1:214491504 SMYD2 0.55 5.86 0.3 1.08e-8 IgG glycosylation; LIHC cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg03264133 chr6:25882463 NA -0.67 -8.4 -0.41 1.18e-15 Intelligence (multi-trait analysis); LIHC cis rs2235573 0.551 rs139892 chr22:38388203 C/T cg03989125 chr22:38214979 NA -0.44 -6.14 -0.32 2.26e-9 Glioblastoma;Glioma; LIHC cis rs57221529 0.766 rs4081846 chr5:574019 G/A cg09021430 chr5:549028 NA -0.45 -9.06 -0.44 1.05e-17 Lung disease severity in cystic fibrosis; LIHC cis rs4819052 0.851 rs875621 chr21:46682295 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.65 0.53 1.21e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs55665837 0.540 rs10766192 chr11:14811686 A/G cg16394018 chr11:14927549 NA 0.39 5.74 0.3 2.04e-8 Vitamin D levels; LIHC cis rs6964587 1.000 rs4644173 chr7:91759597 A/G cg17063962 chr7:91808500 NA 1.03 20.84 0.75 7.83e-63 Breast cancer; LIHC trans rs1005277 0.565 rs2474565 chr10:38380828 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.0 -0.51 2.57e-24 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg21724239 chr8:58056113 NA 0.66 8.01 0.4 1.84e-14 Developmental language disorder (linguistic errors); LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg20295408 chr7:1910781 MAD1L1 -0.49 -7.04 -0.36 1.03e-11 Bipolar disorder and schizophrenia; LIHC cis rs10876993 0.928 rs1678532 chr12:58055197 T/G cg04478727 chr12:58166393 METTL1;FAM119B -0.47 -6.72 -0.34 7.55e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs61677309 1.000 rs59399105 chr11:118168568 C/A cg06090739 chr11:118230722 UBE4A 0.34 6.29 0.32 9.96e-10 Lung cancer in ever smokers; LIHC cis rs2115630 1.000 rs58581703 chr15:85276935 C/T cg11189052 chr15:85197271 WDR73 -0.38 -5.78 -0.3 1.64e-8 P wave terminal force; LIHC cis rs208520 0.526 rs7771233 chr6:66819784 A/G cg07460842 chr6:66804631 NA -1.02 -19.88 -0.73 5.23e-59 Exhaled nitric oxide output; LIHC trans rs7395662 0.591 rs4882233 chr11:48739653 A/G cg03929089 chr4:120376271 NA -0.43 -6.58 -0.34 1.75e-10 HDL cholesterol; LIHC cis rs644799 0.664 rs603625 chr11:95554283 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.8 12.33 0.55 3.82e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9326248 0.954 rs8521 chr11:117067699 C/T cg15534755 chr11:117069859 TAGLN 0.39 6.64 0.34 1.25e-10 Blood protein levels; LIHC cis rs7937890 0.598 rs10734225 chr11:14442994 C/G cg22961513 chr11:14280813 SPON1 -0.43 -6.14 -0.32 2.25e-9 Mitochondrial DNA levels; LIHC cis rs8072100 0.744 rs34537623 chr17:45530203 A/G cg08085267 chr17:45401833 C17orf57 -0.54 -8.11 -0.4 9.18e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.35 0.45 1.17e-18 Electroencephalogram traits; LIHC cis rs67311347 0.524 rs11129869 chr3:40259738 G/A cg13409248 chr3:40428643 ENTPD3 0.41 6.41 0.33 4.79e-10 Renal cell carcinoma; LIHC cis rs523522 1.000 rs523522 chr12:121020250 A/T cg27279351 chr12:120934652 DYNLL1 0.66 11.58 0.53 2.28e-26 High light scatter reticulocyte count; LIHC cis rs4919694 1.000 rs12268849 chr10:104737682 G/A cg04362960 chr10:104952993 NT5C2 0.75 7.56 0.38 3.76e-13 Arsenic metabolism; LIHC cis rs8049040 0.609 rs11866859 chr16:71478888 G/A cg06353428 chr16:71660113 MARVELD3 -0.69 -7.34 -0.37 1.54e-12 Blood protein levels; LIHC trans rs2727020 0.576 rs12293522 chr11:49558425 T/A cg15704280 chr7:45808275 SEPT13 -1.01 -21.99 -0.77 1.96e-67 Coronary artery disease; LIHC cis rs7826238 0.623 rs2976893 chr8:8338219 G/T cg08975724 chr8:8085496 FLJ10661 -0.41 -6.1 -0.31 2.85e-9 Systolic blood pressure; LIHC cis rs2380220 0.808 rs2716070 chr6:95912375 T/C cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs875971 0.862 rs2088655 chr7:65795711 T/C cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC cis rs10751667 0.666 rs7123912 chr11:963936 T/C cg10932868 chr11:921992 NA 0.4 7.48 0.38 6.23e-13 Alzheimer's disease (late onset); LIHC cis rs11711311 0.955 rs12636536 chr3:113474226 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.49 9.41 0.45 7.73e-19 IgG glycosylation; LIHC cis rs700651 0.754 rs1518367 chr2:198807015 T/A cg10820045 chr2:198174542 NA 0.48 7.31 0.37 1.95e-12 Intracranial aneurysm; LIHC cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg19318889 chr4:1322082 MAEA 0.43 5.87 0.3 1.04e-8 Obesity-related traits; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18502306 chr4:8376764 ACOX3 0.45 7.0 0.35 1.4e-11 Longevity; LIHC cis rs6831352 0.918 rs7669636 chr4:100059312 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs8072100 0.676 rs7221345 chr17:45405144 G/A cg08085267 chr17:45401833 C17orf57 -0.73 -12.28 -0.55 5.79e-29 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4665809 1.000 rs4665821 chr2:26309949 A/C cg27170947 chr2:26402098 FAM59B -0.62 -7.71 -0.38 1.37e-13 Gut microbiome composition (summer); LIHC cis rs8177179 0.967 rs6782434 chr3:133438834 C/G cg16262614 chr3:133464971 TF 0.46 10.4 0.49 3.2800000000000002e-22 Iron status biomarkers (transferrin levels); LIHC trans rs1814175 0.817 rs12295885 chr11:50036762 T/G cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.41e-11 Height; LIHC cis rs9560113 0.806 rs9560112 chr13:112183320 A/G cg14154082 chr13:112174009 NA 0.3 6.24 0.32 1.3e-9 Menarche (age at onset); LIHC cis rs12291225 0.585 rs4517475 chr11:14386145 A/G cg19336497 chr11:14380999 RRAS2 -0.68 -14.2 -0.61 2.76e-36 Sense of smell; LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg26338869 chr17:61819248 STRADA 0.53 7.21 0.36 3.73e-12 Height; LIHC cis rs36051895 0.588 rs12340895 chr9:5076691 C/G cg02405213 chr9:5042618 JAK2 0.68 11.72 0.54 6.59e-27 Pediatric autoimmune diseases; LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg12419862 chr22:24373484 LOC391322 0.65 9.22 0.45 3.05e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs546131 0.642 rs836950 chr11:34852020 C/G cg06937548 chr11:34938143 PDHX;APIP -0.58 -7.52 -0.38 4.95e-13 Lung disease severity in cystic fibrosis; LIHC cis rs9325144 0.647 rs12231313 chr12:39101929 C/T cg26384229 chr12:38710491 ALG10B -0.41 -5.89 -0.3 9.16e-9 Morning vs. evening chronotype; LIHC cis rs8028182 0.501 rs11072553 chr15:75932777 C/T cg20655648 chr15:75932815 IMP3 0.46 6.58 0.34 1.8e-10 Sudden cardiac arrest; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25005279 chr10:135113451 TUBGCP2 0.43 6.36 0.33 6.35e-10 Longevity; LIHC cis rs477895 0.713 rs1059440 chr11:63991801 C/T cg04317338 chr11:64019027 PLCB3 -0.85 -10.49 -0.49 1.6400000000000001e-22 Mean platelet volume; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg03395511 chr6:291903 DUSP22 -0.48 -6.39 -0.33 5.36e-10 Menopause (age at onset); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20700762 chr2:192108893 MYO1B -0.32 -7.4 -0.37 1.05e-12 Calcium levels; LIHC cis rs10193935 0.901 rs13022188 chr2:42704423 A/C cg27598129 chr2:42591480 NA 0.7 8.93 0.43 2.7e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs9902453 0.868 rs8066602 chr17:28523085 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.61 9.55 0.46 2.51e-19 Coffee consumption (cups per day); LIHC cis rs6545883 0.929 rs2592352 chr2:61665336 C/T cg14146966 chr2:61757674 XPO1 0.45 7.69 0.38 1.61e-13 Tuberculosis; LIHC cis rs1728785 1.000 rs12918865 chr16:68566546 G/A cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2.05e-9 Ulcerative colitis; LIHC cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg02931644 chr1:25747376 RHCE 0.33 6.94 0.35 2.02e-11 Erythrocyte sedimentation rate; LIHC cis rs6582630 0.576 rs2387837 chr12:38403164 G/T cg26384229 chr12:38710491 ALG10B -0.48 -6.28 -0.32 1.04e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg11764359 chr7:65958608 NA 0.58 6.06 0.31 3.57e-9 Diabetic kidney disease; LIHC cis rs992157 0.730 rs4280446 chr2:219184721 T/C cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.21 0.48 1.49e-21 Colorectal cancer; LIHC cis rs6748734 1.000 rs6748734 chr2:241837452 A/G cg20140201 chr2:241835670 C2orf54 -0.46 -6.13 -0.31 2.37e-9 Urinary metabolites; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg03574000 chr4:103746999 UBE2D3 -0.3 -6.05 -0.31 3.72e-9 Oropharynx cancer; LIHC cis rs736408 0.812 rs746694 chr3:52826620 C/T cg18404041 chr3:52824283 ITIH1 -0.62 -10.11 -0.48 3.32e-21 Bipolar disorder; LIHC cis rs151997 0.962 rs32482 chr5:50207118 T/C cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs9513627 0.915 rs9585070 chr13:100118843 G/C cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs4450131 0.522 rs2272005 chr10:126402100 C/T cg20435097 chr10:126320824 FAM53B 0.65 11.88 0.54 1.77e-27 White blood cell count (basophil); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23335946 chr1:185125966 C1orf25;C1orf26 0.48 6.55 0.33 2.08e-10 Pancreatic cancer; LIHC cis rs73001065 0.818 rs73004975 chr19:19727152 A/G cg03709012 chr19:19516395 GATAD2A 0.83 7.74 0.39 1.1e-13 LDL cholesterol; LIHC cis rs1555322 0.530 rs932562 chr20:33871310 T/C cg03689076 chr20:33865952 NA 0.58 6.68 0.34 9.81e-11 Attention deficit hyperactivity disorder; LIHC cis rs12464483 0.524 rs2602772 chr2:30885263 C/A cg17749961 chr2:30669863 LCLAT1 0.47 6.01 0.31 4.74e-9 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs6088580 0.524 rs11167241 chr20:33250835 C/T cg08999081 chr20:33150536 PIGU -0.43 -7.24 -0.36 2.89e-12 Glomerular filtration rate (creatinine); LIHC cis rs56235845 0.694 rs6875461 chr5:176754665 C/T cg06060754 chr5:176797920 RGS14 -0.48 -6.7 -0.34 8.53e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs9399135 0.967 rs7763836 chr6:135362378 T/C cg24558204 chr6:135376177 HBS1L 0.43 7.06 0.36 9.48e-12 Red blood cell count; LIHC cis rs17401966 0.931 rs12409754 chr1:10457540 T/C cg19773385 chr1:10388646 KIF1B -0.4 -6.52 -0.33 2.6e-10 Hepatocellular carcinoma; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23643835 chr7:45809304 SEPT13 0.4 6.41 0.33 4.93e-10 Longevity; LIHC cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.47 0.46 4.67e-19 Bipolar disorder; LIHC cis rs4803468 0.967 rs13344547 chr19:41945848 G/T cg09537434 chr19:41945824 ATP5SL 1.02 21.05 0.75 1.07e-63 Height; LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC trans rs916888 0.773 rs169201 chr17:44790203 A/G cg13957321 chr17:43675089 NA 0.5 7.97 0.4 2.42e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg11494091 chr17:61959527 GH2 0.44 8.07 0.4 1.21e-14 Prudent dietary pattern; LIHC cis rs6502050 0.835 rs66531647 chr17:80089022 G/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC cis rs735396 0.595 rs1169279 chr12:121455873 C/T cg02403541 chr12:121454288 C12orf43 0.7 13.52 0.59 1.19e-33 N-glycan levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22140136 chr19:10491633 TYK2 0.47 6.82 0.35 4.05e-11 Lung function (FEV1/FVC); LIHC cis rs2421770 0.530 rs3847621 chr11:35364435 G/A cg13971030 chr11:35366721 SLC1A2 -0.45 -7.59 -0.38 3.02e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs7520050 0.807 rs28844317 chr1:46209207 T/C cg24296786 chr1:45957014 TESK2 -0.4 -5.88 -0.3 9.62e-9 Red blood cell count;Reticulocyte count; LIHC cis rs5769707 0.568 rs2011097 chr22:50018069 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.59 -0.42 3.19e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7927592 0.731 rs643609 chr11:68241833 A/G cg01657329 chr11:68192670 LRP5 -0.47 -6.93 -0.35 2.12e-11 Total body bone mineral density; LIHC cis rs1005277 0.579 rs2472174 chr10:38375382 A/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs1144333 1.000 rs5745542 chr1:76365073 C/G cg03433033 chr1:76189801 ACADM 0.54 7.97 0.4 2.39e-14 Attention function in attention deficit hyperactive disorder; LIHC cis rs644799 1.000 rs2508289 chr11:95624669 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.78 0.3 1.72e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12086130 0.892 rs72906804 chr1:51450144 A/G cg07174182 chr1:51127561 FAF1 -0.92 -9.87 -0.47 2.14e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs2997447 0.668 rs59978831 chr1:26446351 T/A cg19633962 chr1:26362018 EXTL1 -0.64 -5.88 -0.3 9.64e-9 QRS complex (12-leadsum); LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg08219700 chr8:58056026 NA -0.5 -6.92 -0.35 2.21e-11 Developmental language disorder (linguistic errors); LIHC cis rs6060717 0.702 rs6060756 chr20:34608479 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.49 8.56 0.42 3.9e-16 Hip circumference adjusted for BMI; LIHC cis rs10905065 0.965 rs7100576 chr10:5784649 G/A cg11519256 chr10:5708881 ASB13 0.46 6.11 0.31 2.66e-9 Menopause (age at onset); LIHC cis rs992157 0.764 rs13020391 chr2:219184436 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.68 -9.49 -0.46 4.2e-19 Colorectal cancer; LIHC cis rs1865760 1.000 rs6905887 chr6:25912103 T/C cg17691542 chr6:26056736 HIST1H1C 0.39 5.91 0.3 8.47e-9 Height; LIHC cis rs16958440 0.867 rs16949275 chr18:44700703 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.805 rs4818855 chr21:45038951 C/T cg04455712 chr21:45112962 RRP1B 0.42 7.36 0.37 1.4e-12 Mean corpuscular volume; LIHC cis rs760805 1.000 rs3845302 chr1:25259884 C/G cg22509179 chr1:25234806 RUNX3 -0.38 -7.82 -0.39 6.6e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7917772 0.636 rs7911747 chr10:104528890 A/G cg22532475 chr10:104410764 TRIM8 0.36 6.45 0.33 3.71e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1005277 0.579 rs2472183 chr10:38392495 T/G cg00409905 chr10:38381863 ZNF37A -0.6 -10.39 -0.49 3.67e-22 Extrinsic epigenetic age acceleration; LIHC cis rs7917772 0.582 rs10786687 chr10:104336994 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.17e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11608355 0.545 rs11613021 chr12:109897998 T/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs8062405 0.728 rs11642449 chr16:28896015 C/T cg07451762 chr16:28383216 NA 0.33 6.03 0.31 4.23e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.679 rs16921677 chr8:58052431 T/C cg20607798 chr8:58055168 NA 0.45 6.05 0.31 3.76e-9 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12463199 chr20:49126897 PTPN1 0.37 6.31 0.32 8.52e-10 Cognitive function; LIHC cis rs2976388 1.000 rs2920296 chr8:143763109 A/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg11070056 chr1:107600091 PRMT6 -0.72 -12.31 -0.55 4.65e-29 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11997175 0.624 rs17701219 chr8:33728795 T/A ch.8.33884649F chr8:33765107 NA 0.32 5.96 0.31 6.15e-9 Body mass index; LIHC cis rs2204008 0.627 rs10878486 chr12:38148601 T/G cg13010199 chr12:38710504 ALG10B 0.49 5.78 0.3 1.68e-8 Bladder cancer; LIHC cis rs875971 0.862 rs6959268 chr7:65812966 G/A cg18252515 chr7:66147081 NA 0.44 6.34 0.32 7.48e-10 Aortic root size; LIHC cis rs7534824 0.543 rs6577221 chr1:101420406 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 7.53 0.38 4.57e-13 Refractive astigmatism; LIHC cis rs11971779 0.680 rs2355783 chr7:139075879 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs4663866 0.901 rs3739066 chr2:239184124 G/T cg16914508 chr2:239161102 PER2 0.8 5.84 0.3 1.23e-8 Irritable bowel syndrome; LIHC cis rs2224391 0.955 rs2773322 chr6:5263065 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs875971 0.520 rs12666485 chr7:65625122 T/C cg11764359 chr7:65958608 NA 0.51 7.08 0.36 8.1e-12 Aortic root size; LIHC cis rs7959452 0.558 rs1478464 chr12:69779789 G/C cg22834771 chr12:69754056 YEATS4 -0.52 -9.17 -0.44 4.63e-18 Blood protein levels; LIHC cis rs6722750 0.840 rs6712700 chr2:64374041 A/G cg22352474 chr2:64371530 PELI1 0.64 9.71 0.46 7.5599999999999994e-20 Neuroticism; LIHC cis rs798554 0.679 rs2644300 chr7:2883071 G/A cg13628971 chr7:2884303 GNA12 0.6 9.95 0.47 1.21e-20 Height; LIHC cis rs12744310 1.000 rs12029950 chr1:41753165 G/A cg03962019 chr1:41807865 NA 0.38 6.1 0.31 2.82e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs875971 0.545 rs10950025 chr7:65623933 G/A cg26939375 chr7:64535504 NA 0.41 6.47 0.33 3.36e-10 Aortic root size; LIHC cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg20399509 chr21:47717575 C21orf57 0.37 5.83 0.3 1.28e-8 Testicular germ cell tumor; LIHC cis rs13191362 0.935 rs13193473 chr6:162966852 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.74 0.3 2.07e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12477438 0.765 rs2309454 chr2:99595418 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.24 -0.41 3.62e-15 Chronic sinus infection; LIHC cis rs477692 0.905 rs570967 chr10:131421330 T/G cg05714579 chr10:131428358 MGMT 0.49 8.31 0.41 2.27e-15 Response to temozolomide; LIHC cis rs8177253 1.000 rs1358023 chr3:133484393 T/C cg12373951 chr3:133503437 NA 0.69 12.31 0.55 4.59e-29 Iron status biomarkers; LIHC cis rs9916302 0.904 rs801420 chr17:37466103 C/G cg00129232 chr17:37814104 STARD3 0.39 6.25 0.32 1.23e-9 Glomerular filtration rate (creatinine); LIHC cis rs116095464 0.558 rs3213838 chr5:223890 G/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg21016266 chr12:122356598 WDR66 -0.44 -6.99 -0.35 1.41e-11 Mean corpuscular volume; LIHC cis rs10256972 0.869 rs4720158 chr7:1040325 A/G cg04025307 chr7:1156635 C7orf50 0.48 7.95 0.39 2.78e-14 Longevity;Endometriosis; LIHC cis rs782590 0.774 rs2627773 chr2:55900459 A/G cg18811423 chr2:55921094 PNPT1 0.89 14.17 0.61 3.55e-36 Metabolic syndrome; LIHC cis rs2050392 0.557 rs306588 chr10:30723593 G/A cg25182066 chr10:30743637 MAP3K8 -0.63 -10.11 -0.48 3.45e-21 Inflammatory bowel disease; LIHC cis rs12478296 0.681 rs55802421 chr2:243033962 C/T cg18898632 chr2:242989856 NA -0.57 -7.59 -0.38 3.11e-13 Obesity-related traits; LIHC trans rs2727020 0.521 rs7930855 chr11:49521660 C/T cg18944383 chr4:111397179 ENPEP -0.35 -8.15 -0.4 7.15e-15 Coronary artery disease; LIHC cis rs7116495 1.000 rs1783961 chr11:71576095 A/C cg26138937 chr11:71823887 C11orf51 0.71 6.93 0.35 2.15e-11 Severe influenza A (H1N1) infection; LIHC cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg06634786 chr22:41940651 POLR3H -0.81 -8.45 -0.42 8.65e-16 Vitiligo; LIHC cis rs9910055 0.530 rs2269908 chr17:42294198 G/C cg10896456 chr17:42255109 ASB16;C17orf65 0.42 7.32 0.37 1.8e-12 Total body bone mineral density; LIHC cis rs9902453 0.967 rs3813034 chr17:28524804 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.09 0.44 8.02e-18 Coffee consumption (cups per day); LIHC cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg19539972 chr4:7069911 GRPEL1 0.7 10.11 0.48 3.36e-21 Monocyte percentage of white cells; LIHC cis rs644799 0.930 rs2186782 chr11:95649543 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.45 6.17 0.32 1.97e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6442522 0.671 rs2305615 chr3:15517025 G/A cg16303742 chr3:15540471 COLQ 0.39 6.48 0.33 3.18e-10 Uric acid levels; LIHC cis rs4788570 0.615 rs4788822 chr16:71681515 A/G cg06353428 chr16:71660113 MARVELD3 1.45 15.73 0.65 2.59e-42 Intelligence (multi-trait analysis); LIHC cis rs7395581 0.797 rs10742801 chr11:47342220 A/C cg25783544 chr11:47291846 MADD 0.4 5.74 0.3 2.04e-8 HDL cholesterol; LIHC trans rs12478296 0.818 rs57194240 chr2:243011545 A/G cg01596870 chr19:55963115 NA -0.67 -9.66 -0.46 1.09e-19 Obesity-related traits; LIHC cis rs208520 0.690 rs207102 chr6:66795671 G/A cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01719123 chr8:28244050 ZNF395 0.5 7.0 0.35 1.33e-11 Lung function (FEV1/FVC); LIHC cis rs9902453 0.967 rs28792710 chr17:28450015 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.61 9.46 0.46 5.05e-19 Coffee consumption (cups per day); LIHC cis rs743757 1.000 rs743757 chr3:50476378 C/G cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.48 -7.39 -0.37 1.17e-12 Diastolic blood pressure; LIHC cis rs7789940 1.000 rs7789940 chr7:75951230 A/G cg10167463 chr7:75959203 YWHAG -0.45 -6.95 -0.35 1.87e-11 Multiple sclerosis; LIHC cis rs1552244 0.572 rs41464050 chr3:10158393 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.83 -10.26 -0.48 1.08e-21 Alzheimer's disease; LIHC cis rs2019137 0.589 rs7560701 chr2:114026882 C/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.43 5.76 0.3 1.86e-8 Lymphocyte counts; LIHC cis rs35160687 0.623 rs35408390 chr2:86471782 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.39 6.38 0.33 5.64e-10 Night sleep phenotypes; LIHC cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg18404041 chr3:52824283 ITIH1 -0.64 -10.67 -0.5 3.99e-23 Bipolar disorder; LIHC trans rs7618501 0.602 rs2624853 chr3:50128893 A/G cg21659725 chr3:3221576 CRBN -0.66 -10.5 -0.49 1.58e-22 Intelligence (multi-trait analysis); LIHC cis rs6445975 0.715 rs3773007 chr3:58269566 G/T cg23715586 chr3:58305044 RPP14 -0.38 -6.42 -0.33 4.58e-10 Systemic lupus erythematosus; LIHC cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg12379764 chr21:47803548 PCNT 0.6 8.46 0.42 8.19e-16 Testicular germ cell tumor; LIHC cis rs2280018 0.526 rs2941257 chr16:15166445 T/C cg07549590 chr16:15018862 NA -0.41 -7.86 -0.39 5.03e-14 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6733011 0.560 rs7579189 chr2:99464718 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.42 -5.83 -0.3 1.27e-8 Bipolar disorder; LIHC cis rs2257205 0.667 rs74961279 chr17:56904991 C/T cg12560992 chr17:57184187 TRIM37 0.67 7.23 0.36 3.24e-12 Pancreatic cancer; LIHC cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.26 0.45 2.37e-18 Bipolar disorder; LIHC cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg07061783 chr6:25882402 NA -0.47 -6.53 -0.33 2.38e-10 Blood metabolite levels; LIHC trans rs4718428 0.705 rs13220977 chr7:66337648 A/T cg10756647 chr7:56101905 PSPH -0.63 -8.52 -0.42 5.08e-16 Corneal structure; LIHC cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg12463550 chr7:65579703 CRCP 0.68 7.09 0.36 7.93e-12 Diabetic kidney disease; LIHC cis rs12908161 1.000 rs35630683 chr15:85349231 T/C cg17507749 chr15:85114479 UBE2QP1 0.63 7.08 0.36 8e-12 Schizophrenia; LIHC cis rs743757 0.938 rs2236981 chr3:50488845 A/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.51 7.95 0.4 2.66e-14 Diastolic blood pressure; LIHC cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg06481639 chr22:41940642 POLR3H -0.65 -6.64 -0.34 1.23e-10 Vitiligo; LIHC cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs11229030 0.893 rs2581925 chr11:57207414 G/A cg00522883 chr11:57194120 SLC43A3 -0.41 -5.88 -0.3 9.96e-9 Crohn's disease; LIHC cis rs992157 1.000 rs2168704 chr2:219142492 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.05 0.58 7.07e-32 Colorectal cancer; LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg07755735 chr2:20870362 GDF7 -0.45 -9.69 -0.46 8.99e-20 Abdominal aortic aneurysm; LIHC cis rs1707322 1.000 rs785468 chr1:46521517 G/A cg06784218 chr1:46089804 CCDC17 -0.36 -6.5 -0.33 2.8e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg02951883 chr7:2050386 MAD1L1 -0.52 -7.72 -0.39 1.26e-13 Bipolar disorder and schizophrenia; LIHC cis rs798554 0.704 rs798513 chr7:2782493 C/T cg13628971 chr7:2884303 GNA12 0.4 6.36 0.33 6.41e-10 Height; LIHC cis rs9473924 0.542 rs9473925 chr6:50834565 T/C cg14470998 chr6:50812995 TFAP2B 0.93 10.64 0.5 5.15e-23 Body mass index; LIHC cis rs8062405 1.000 rs62037371 chr16:28890131 C/A cg16576597 chr16:28551801 NUPR1 0.38 6.23 0.32 1.39e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.14 0.32 2.28e-9 Total body bone mineral density; LIHC cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg07061783 chr6:25882402 NA -0.48 -6.69 -0.34 9.05e-11 Blood metabolite levels; LIHC cis rs3096299 0.869 rs748941 chr16:89440754 T/A cg08392591 chr16:89556376 ANKRD11 0.39 5.91 0.3 8.31e-9 Multiple myeloma (IgH translocation); LIHC cis rs9611565 0.512 rs139562 chr22:42196684 G/C cg03806693 chr22:41940476 POLR3H -0.97 -10.49 -0.49 1.69e-22 Vitiligo; LIHC cis rs2153535 0.580 rs7743686 chr6:8526111 A/G cg23788917 chr6:8435910 SLC35B3 0.63 9.02 0.44 1.37e-17 Motion sickness; LIHC cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs4906332 0.899 rs12888042 chr14:103891709 G/A cg04998671 chr14:104000505 TRMT61A -0.45 -6.26 -0.32 1.12e-9 Coronary artery disease; LIHC cis rs2439831 0.681 rs478104 chr15:43594900 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.76 11.51 0.53 4e-26 Lung cancer in ever smokers; LIHC cis rs6570726 0.738 rs7746330 chr6:145899257 A/C cg05347473 chr6:146136440 FBXO30 0.38 5.92 0.3 7.87e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6540556 0.682 rs932335 chr1:209905734 G/C cg05527609 chr1:210001259 C1orf107 -0.58 -7.83 -0.39 6.22e-14 Red blood cell count; LIHC cis rs2832191 0.791 rs2832198 chr21:30498240 C/T cg24692254 chr21:30365293 RNF160 0.57 9.75 0.47 5.63e-20 Dental caries; LIHC cis rs798554 0.731 rs2283779 chr7:2815140 G/A cg13628971 chr7:2884303 GNA12 0.41 6.53 0.33 2.37e-10 Height; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg10150615 chr22:24372951 LOC391322 -0.58 -8.55 -0.42 4.11e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg25072359 chr17:41440525 NA 0.39 6.2 0.32 1.59e-9 Menopause (age at onset); LIHC cis rs34540877 1.000 rs35760204 chr19:33130534 C/G cg22980127 chr19:33182716 NUDT19 1.03 6.81 0.35 4.36e-11 Red cell distribution width; LIHC cis rs7618501 0.571 rs2240329 chr3:50107512 G/A cg24110177 chr3:50126178 RBM5 0.49 8.02 0.4 1.73e-14 Intelligence (multi-trait analysis); LIHC cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg16497277 chr3:49208875 KLHDC8B -0.5 -6.27 -0.32 1.06e-9 Menarche (age at onset); LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg09177884 chr7:1199841 ZFAND2A -0.41 -5.73 -0.3 2.21e-8 Longevity;Endometriosis; LIHC cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg08888203 chr3:10149979 C3orf24 0.6 6.5 0.33 2.8e-10 Alzheimer's disease; LIHC cis rs1163251 0.756 rs539799 chr1:120208472 C/T cg19096424 chr1:120255104 PHGDH 0.5 6.34 0.32 7.34e-10 Blood metabolite levels; LIHC trans rs2727020 0.567 rs1164687 chr11:49290669 G/A cg15704280 chr7:45808275 SEPT13 0.77 11.7 0.53 8.12e-27 Coronary artery disease; LIHC cis rs1862618 0.671 rs2591968 chr5:56233541 A/G cg12311346 chr5:56204834 C5orf35 -0.46 -6.27 -0.32 1.08e-9 Initial pursuit acceleration; LIHC cis rs2286885 0.965 rs741024 chr9:129251821 A/G cg15282417 chr9:129245246 FAM125B -0.39 -6.28 -0.32 1.04e-9 Intraocular pressure; LIHC cis rs1256061 0.624 rs1760988 chr14:64696813 A/G cg23250157 chr14:64679961 SYNE2 0.43 6.19 0.32 1.76e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs916888 0.738 rs199515 chr17:44856641 C/G cg13957321 chr17:43675089 NA -0.44 -7.28 -0.37 2.27e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs62103177 0.608 rs613847 chr18:77845644 A/G cg05926928 chr17:57297772 GDPD1 -0.63 -7.03 -0.36 1.1e-11 Opioid sensitivity; LIHC cis rs1552244 0.554 rs13079240 chr3:10047246 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs858239 0.570 rs6968242 chr7:23167411 T/G cg23682824 chr7:23144976 KLHL7 0.45 6.68 0.34 9.63e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs1005277 0.602 rs1740743 chr10:38519222 C/T cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs7589728 1.000 rs7425670 chr2:88522028 C/T cg04511125 chr2:88470314 THNSL2 0.78 7.32 0.37 1.83e-12 Plasma clusterin levels; LIHC cis rs2120019 1.000 rs7173833 chr15:75369618 C/T cg17294928 chr15:75287854 SCAMP5 -0.48 -7.44 -0.37 8.11e-13 Blood trace element (Zn levels); LIHC cis rs9560113 0.573 rs9560133 chr13:112240013 C/A cg10483660 chr13:112241077 NA 0.25 6.27 0.32 1.08e-9 Menarche (age at onset); LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 6.57 0.33 1.87e-10 Lymphocyte counts; LIHC cis rs55882075 0.967 rs12656648 chr5:179152106 C/A cg14593053 chr5:179126677 CANX 0.4 7.2 0.36 3.74e-12 Monocyte percentage of white cells; LIHC cis rs12477438 0.798 rs12477754 chr2:99628073 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.72 -0.5 2.62e-23 Chronic sinus infection; LIHC cis rs7412746 0.634 rs12562939 chr1:150951452 A/C cg15448220 chr1:150897856 SETDB1 0.44 6.79 0.34 4.95e-11 Melanoma; LIHC cis rs10791097 0.694 rs4457753 chr11:130755575 A/G cg09137382 chr11:130731461 NA 0.4 5.93 0.31 7.39e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11122272 0.701 rs2790887 chr1:231523724 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1018836 0.851 rs2023624 chr8:91618874 T/C cg16814680 chr8:91681699 NA -0.61 -9.78 -0.47 4.52e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.679 rs16921687 chr8:58053514 T/C cg02290350 chr8:58132656 NA 0.31 6.89 0.35 2.77e-11 Developmental language disorder (linguistic errors); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg02804564 chr10:112679224 NCRNA00081;SHOC2 0.41 6.54 0.33 2.19e-10 Morning vs. evening chronotype; LIHC cis rs7044106 0.791 rs7036196 chr9:123479457 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.91 0.39 3.59e-14 Hip circumference adjusted for BMI; LIHC cis rs875971 0.522 rs1617484 chr7:65463095 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.34 6.47 0.33 3.4e-10 Aortic root size; LIHC cis rs12286929 0.898 rs11215384 chr11:115023851 C/G cg04055981 chr11:115044050 NA 0.42 6.66 0.34 1.08e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg14893161 chr1:205819251 PM20D1 0.66 9.58 0.46 2.12e-19 Menarche (age at onset); LIHC trans rs7246657 0.714 rs12972195 chr19:37752505 T/C cg10208301 chr11:6592745 DNHD1 0.45 6.39 0.33 5.4e-10 Coronary artery calcification; LIHC cis rs7589728 0.563 rs80324973 chr2:88447264 T/G cg14558114 chr2:88469736 THNSL2 0.59 5.72 0.3 2.3e-8 Plasma clusterin levels; LIHC cis rs1728785 0.901 rs1103286 chr16:68578625 C/T cg02972257 chr16:68554789 NA -0.54 -6.15 -0.32 2.15e-9 Ulcerative colitis; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.59 11.16 0.52 7.09e-25 Prudent dietary pattern; LIHC cis rs6442522 0.611 rs1983085 chr3:15529543 C/T cg16303742 chr3:15540471 COLQ -0.39 -6.32 -0.32 8.25e-10 Uric acid levels; LIHC cis rs780096 0.546 rs4425043 chr2:27733452 G/A cg05484376 chr2:27715224 FNDC4 0.4 6.74 0.34 6.89e-11 Total body bone mineral density; LIHC cis rs3741798 1.000 rs3741798 chr12:12496086 C/T cg08615371 chr12:12503544 MANSC1 0.9 7.32 0.37 1.74e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg03264133 chr6:25882463 NA -0.71 -9.26 -0.45 2.25e-18 Intelligence (multi-trait analysis); LIHC cis rs10927875 0.632 rs4661666 chr1:16162471 C/A cg21385522 chr1:16154831 NA -1.05 -17.45 -0.69 3.27e-49 Dilated cardiomyopathy; LIHC cis rs2404602 0.716 rs56216512 chr15:76686936 T/C cg03037974 chr15:76606532 NA 0.8 16.43 0.66 3.98e-45 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20314438 chr6:126661369 C6orf173 0.49 6.63 0.34 1.35e-10 Pancreatic cancer; LIHC cis rs9814567 1.000 rs9884031 chr3:134256500 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12477438 0.520 rs7572660 chr2:99788582 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.21 0.61 2.47e-36 Chronic sinus infection; LIHC cis rs6061231 0.793 rs2427320 chr20:60976723 A/G cg22601191 chr20:60968625 CABLES2 0.45 5.81 0.3 1.4e-8 Colorectal cancer; LIHC cis rs11229555 0.645 rs35279927 chr11:58212129 G/T cg15696309 chr11:58395628 NA -0.65 -7.63 -0.38 2.37e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs12220238 0.841 rs10824146 chr10:76076779 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.27 0.32 1.07e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2120019 0.938 rs3850093 chr15:75318482 A/G cg09165964 chr15:75287851 SCAMP5 0.65 10.37 0.49 4.5e-22 Blood trace element (Zn levels); LIHC cis rs523522 0.962 rs4767914 chr12:120993817 C/T cg27279351 chr12:120934652 DYNLL1 0.67 12.08 0.55 3.21e-28 High light scatter reticulocyte count; LIHC cis rs904251 0.600 rs4714068 chr6:37455642 A/C cg01843034 chr6:37503916 NA -0.38 -6.38 -0.33 5.74e-10 Cognitive performance; LIHC cis rs1005277 0.541 rs2263163 chr10:38389887 G/A cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs9590974 0.663 rs837 chr13:47224772 G/A cg04092803 chr13:47240378 LRCH1 0.26 5.73 0.3 2.17e-8 PR segment; LIHC cis rs10463316 0.832 rs246486 chr5:150727880 C/T cg03212797 chr5:150827313 SLC36A1 0.47 7.12 0.36 6.26e-12 Metabolite levels (Pyroglutamine); LIHC cis rs2180341 0.961 rs7775493 chr6:127615000 C/A cg27446573 chr6:127587934 RNF146 1.03 15.95 0.65 3.18e-43 Breast cancer; LIHC cis rs1577917 1.000 rs1337850 chr6:86729103 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.04 -0.48 5.87e-21 Response to antipsychotic treatment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01457413 chr19:9879603 ZNF846 0.44 6.2 0.32 1.62e-9 Lung function (FEV1/FVC); LIHC cis rs2012796 1.000 rs7153469 chr14:81820979 T/G cg02996355 chr14:81879375 NA 0.45 6.79 0.34 5.04e-11 Night sleep phenotypes; LIHC cis rs4919694 0.572 rs12243903 chr10:104906992 T/C cg04362960 chr10:104952993 NT5C2 0.81 7.14 0.36 5.64e-12 Arsenic metabolism; LIHC cis rs1348850 0.914 rs12616443 chr2:178315751 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.13 0.58 3.64e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2842992 1.000 rs2758322 chr6:160075188 G/T cg26839252 chr6:160211577 TCP1;MRPL18 0.35 5.81 0.3 1.43e-8 Age-related macular degeneration (geographic atrophy); LIHC cis rs7666738 0.830 rs2865951 chr4:99040191 C/T cg05340658 chr4:99064831 C4orf37 0.7 12.73 0.57 1.15e-30 Colonoscopy-negative controls vs population controls; LIHC cis rs35883536 0.647 rs10875314 chr1:101043207 G/C cg14515779 chr1:101123966 NA 0.46 6.6 0.34 1.61e-10 Monocyte count; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg26075905 chr14:102391388 PPP2R5C 0.52 6.3 0.32 9.26e-10 Lung function (FEV1); LIHC cis rs10838687 0.736 rs2242262 chr11:47266540 G/T cg25783544 chr11:47291846 MADD 0.46 5.89 0.3 9.29e-9 Proinsulin levels; LIHC cis rs240764 0.658 rs6909880 chr6:101179354 A/C cg09795085 chr6:101329169 ASCC3 -0.57 -8.19 -0.41 5.13e-15 Neuroticism; LIHC cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg23758822 chr17:41437982 NA 0.92 17.07 0.68 1.09e-47 Menopause (age at onset); LIHC cis rs67478160 0.655 rs4900598 chr14:104281541 T/C cg08213375 chr14:104286397 PPP1R13B 0.65 12.64 0.56 2.5e-30 Schizophrenia; LIHC cis rs67478160 0.575 rs8014294 chr14:104322983 A/G cg08213375 chr14:104286397 PPP1R13B 0.51 9.28 0.45 1.98e-18 Schizophrenia; LIHC cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg03264133 chr6:25882463 NA -0.63 -8.84 -0.43 5.07e-17 Blood metabolite levels; LIHC cis rs748404 0.660 rs2602141 chr15:43724646 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.78 0.39 8.87e-14 Lung cancer; LIHC cis rs11190604 1.000 rs10883497 chr10:102228519 A/G cg07080220 chr10:102295463 HIF1AN 0.45 6.31 0.32 8.56e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17125944 0.686 rs12435704 chr14:53346574 T/C cg00686598 chr14:53173677 PSMC6 -0.82 -8.98 -0.44 1.81e-17 Alzheimer's disease (late onset); LIHC cis rs7520050 0.966 rs11211199 chr1:46287869 T/C cg03146154 chr1:46216737 IPP -0.39 -6.5 -0.33 2.88e-10 Red blood cell count;Reticulocyte count; LIHC cis rs11112613 0.713 rs11112590 chr12:105951376 C/G cg03607813 chr12:105948248 NA -0.6 -11.38 -0.52 1.19e-25 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs6448317 0.539 rs13113895 chr4:24932077 T/C cg21108841 chr4:24914750 CCDC149 -0.49 -6.7 -0.34 8.38e-11 Heschl's gyrus morphology; LIHC cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg11987759 chr7:65425863 GUSB -0.38 -6.02 -0.31 4.52e-9 Calcium levels; LIHC cis rs2228479 0.850 rs11644213 chr16:89837367 C/T cg06558623 chr16:89946397 TCF25 -0.85 -11.3 -0.52 2.33e-25 Skin colour saturation; LIHC cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.8 0.3 1.54e-8 Menopause (age at onset); LIHC cis rs2573652 0.722 rs12904962 chr15:100544113 A/G cg09918751 chr15:100517450 ADAMTS17 0.71 12.72 0.57 1.33e-30 Height; LIHC cis rs10504229 1.000 rs67096506 chr8:58195655 G/A cg02290350 chr8:58132656 NA 0.47 9.18 0.44 4.31e-18 Developmental language disorder (linguistic errors); LIHC cis rs57502260 0.749 rs67446678 chr11:68227466 C/T cg20283391 chr11:68216788 NA -0.46 -5.71 -0.3 2.43e-8 Total body bone mineral density (age 45-60); LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg11235426 chr6:292522 DUSP22 0.49 6.65 0.34 1.14e-10 Menopause (age at onset); LIHC cis rs3762637 1.000 rs11932 chr3:122141135 A/G cg24169773 chr3:122142474 KPNA1 0.49 9.89 0.47 1.92e-20 LDL cholesterol levels; LIHC cis rs17685 0.753 rs3757593 chr7:75678735 G/A cg04610667 chr7:75704037 NA 0.35 6.2 0.32 1.61e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7927771 0.524 rs4752860 chr11:47705015 C/A cg20307385 chr11:47447363 PSMC3 -0.71 -10.68 -0.5 3.68e-23 Subjective well-being; LIHC cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg20607798 chr8:58055168 NA 0.66 8.05 0.4 1.35e-14 Developmental language disorder (linguistic errors); LIHC cis rs7309 0.810 rs11684253 chr2:162034536 G/T cg21518248 chr2:162101506 NA 0.46 7.09 0.36 7.93e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs6545883 0.965 rs3771258 chr2:61764140 C/T cg15711740 chr2:61764176 XPO1 -0.44 -6.18 -0.32 1.87e-9 Tuberculosis; LIHC cis rs7552404 1.000 rs7524467 chr1:76194054 C/G cg10523679 chr1:76189770 ACADM 0.64 8.73 0.43 1.11e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs780094 0.544 rs780110 chr2:27685388 G/A cg27432699 chr2:27873401 GPN1 -0.45 -6.25 -0.32 1.22e-9 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs6754311 0.551 rs2304599 chr2:136528004 C/G cg15123519 chr2:136567270 LCT 0.35 6.64 0.34 1.26e-10 Mosquito bite size; LIHC cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg27286337 chr10:134555280 INPP5A 0.92 13.04 0.58 7.93e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs1814175 0.616 rs10839342 chr11:49742687 A/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.59 -0.74 7.56e-62 Height; LIHC trans rs2727020 0.576 rs10839305 chr11:49598733 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -22.09 -0.77 8.21e-68 Coronary artery disease; LIHC cis rs11628318 0.614 rs3783383 chr14:103177420 G/C cg12046867 chr14:103022105 NA 0.47 7.33 0.37 1.72e-12 Platelet count; LIHC cis rs5753037 0.702 rs249398 chr22:30214704 G/C cg01021169 chr22:30184971 ASCC2 -0.35 -6.69 -0.34 9.37e-11 Type 1 diabetes; LIHC cis rs7959452 0.532 rs2291005 chr12:69764388 A/G cg14784868 chr12:69753453 YEATS4 0.95 20.5 0.74 1.68e-61 Blood protein levels; LIHC cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06134974 chr12:51477539 CSRNP2 0.43 6.23 0.32 1.37e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1568889 1.000 rs7112860 chr11:28151609 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 7.06 0.36 9.28e-12 Bipolar disorder; LIHC cis rs4742903 0.967 rs4742904 chr9:106856952 C/T cg14250997 chr9:106856677 SMC2 0.42 7.3 0.37 2.03e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg02475777 chr4:1388615 CRIPAK -0.48 -7.04 -0.36 1.03e-11 Obesity-related traits; LIHC cis rs644799 0.965 rs534488 chr11:95562327 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.31 0.68 1.13e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs35306767 0.761 rs12359796 chr10:1021479 G/C cg20503657 chr10:835505 NA 0.84 7.51 0.38 5.07e-13 Eosinophil percentage of granulocytes; LIHC cis rs712039 0.652 rs60112577 chr17:35833209 G/A cg16670864 chr17:35848621 DUSP14 0.34 5.73 0.3 2.19e-8 Tuberculosis; LIHC cis rs12928939 0.517 rs8049508 chr16:71978313 C/T cg03805757 chr16:71968109 PKD1L3 -0.91 -13.06 -0.58 6.52e-32 Post bronchodilator FEV1; LIHC cis rs10870270 1.000 rs7199 chr10:133769848 C/G cg08754478 chr10:133766260 PPP2R2D -0.55 -8.08 -0.4 1.09e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs12701220 0.655 rs34696066 chr7:1140919 C/T cg18765753 chr7:1198926 ZFAND2A -0.42 -5.94 -0.31 6.91e-9 Bronchopulmonary dysplasia; LIHC cis rs3820068 0.532 rs1547034 chr1:15919049 T/A cg17385448 chr1:15911702 AGMAT 0.34 5.96 0.31 6.15e-9 Systolic blood pressure; LIHC cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg12463550 chr7:65579703 CRCP 0.67 7.02 0.36 1.17e-11 Diabetic kidney disease; LIHC cis rs2834188 1.000 rs2409488 chr21:34688914 A/C cg04842828 chr21:34696676 IFNAR1 0.45 6.09 0.31 3.1e-9 Narcolepsy; LIHC cis rs9649465 0.522 rs662705 chr7:123431594 A/C cg03229431 chr7:123269106 ASB15 0.43 9.16 0.44 4.81e-18 Migraine; LIHC cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg20607798 chr8:58055168 NA 0.7 8.57 0.42 3.61e-16 Developmental language disorder (linguistic errors); LIHC cis rs1712517 1.000 rs1712517 chr10:105033015 C/T cg05636881 chr10:105038444 INA 0.4 6.3 0.32 8.99e-10 Migraine; LIHC cis rs1215050 0.791 rs2658477 chr4:98850993 G/A cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.61e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs67311347 1.000 rs9848083 chr3:40466979 A/G cg09455208 chr3:40491958 NA -0.32 -6.39 -0.33 5.55e-10 Renal cell carcinoma; LIHC cis rs17818399 0.926 rs7590693 chr2:46823992 G/A cg02822958 chr2:46747628 ATP6V1E2 0.49 7.49 0.38 5.99e-13 Height; LIHC cis rs2976388 1.000 rs2585179 chr8:143774193 G/A cg06565975 chr8:143823917 SLURP1 -0.31 -5.79 -0.3 1.56e-8 Urinary tract infection frequency; LIHC cis rs11628318 0.614 rs7145737 chr14:103121784 T/A cg01864069 chr14:103024347 NA 0.45 7.01 0.35 1.3e-11 Platelet count; LIHC cis rs240110 0.570 rs966741 chr6:101218375 A/G cg09795085 chr6:101329169 ASCC3 -0.41 -5.73 -0.3 2.19e-8 Neuroticism; LIHC cis rs17685 0.712 rs2158867 chr7:75815141 C/A cg01364799 chr7:75623366 TMEM120A -0.51 -7.86 -0.39 4.95e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6542838 0.702 rs4851177 chr2:99535188 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.2 -0.32 1.58e-9 Fear of minor pain; LIHC cis rs2607426 1.000 rs2604877 chr19:41275048 T/C cg20631044 chr19:41255890 C19orf54;SNRPA -0.49 -5.88 -0.3 9.77e-9 Blood protein levels; LIHC cis rs6840360 1.000 rs12502055 chr4:152596668 G/A cg22705602 chr4:152727874 NA -0.3 -6.44 -0.33 4.04e-10 Intelligence (multi-trait analysis); LIHC cis rs2841277 0.708 rs10083496 chr14:105402786 G/A cg15352829 chr14:105391018 PLD4 -0.43 -9.22 -0.45 3.04e-18 Rheumatoid arthritis; LIHC cis rs2303759 0.918 rs7251704 chr19:49890873 T/G cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.84 0.43 4.99e-17 Multiple sclerosis; LIHC cis rs7100689 0.577 rs2185427 chr10:82056667 G/T cg00277334 chr10:82204260 NA 0.55 6.74 0.34 6.86e-11 Post bronchodilator FEV1; LIHC cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg09323728 chr8:95962352 TP53INP1 -0.28 -6.14 -0.32 2.29e-9 Type 2 diabetes; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg00911488 chr4:106068604 TET2 -0.4 -6.16 -0.32 2e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7149337 0.805 rs3007164 chr14:51646935 A/G cg23942311 chr14:51606299 NA 0.35 7.18 0.36 4.5e-12 Cancer; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg06873352 chr17:61820015 STRADA 0.71 12.21 0.55 1.02e-28 Prudent dietary pattern; LIHC cis rs35362007 0.530 rs79171925 chr14:96003075 T/C cg13511115 chr14:96000878 GLRX5;SNHG10;SCARNA13 0.87 7.09 0.36 7.84e-12 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg00656387 chr3:40428638 ENTPD3 -0.51 -8.72 -0.43 1.24e-16 Renal cell carcinoma; LIHC cis rs2576037 0.583 rs501882 chr18:44411066 A/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.83 -0.3 1.29e-8 Personality dimensions; LIHC cis rs1865760 0.566 rs9295686 chr6:26081983 G/C cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs1577917 0.876 rs12201992 chr6:86618219 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13296214 chr12:9436248 LOC642846 0.48 9.04 0.44 1.15e-17 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2832191 0.967 rs2832216 chr21:30521921 C/T cg24692254 chr21:30365293 RNF160 0.49 8.54 0.42 4.42e-16 Dental caries; LIHC cis rs2274273 0.840 rs6573020 chr14:55871452 C/T cg01864836 chr14:55583639 NA -0.35 -6.35 -0.32 6.86e-10 Protein biomarker; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg26338869 chr17:61819248 STRADA 0.61 8.91 0.43 3.08e-17 Prudent dietary pattern; LIHC cis rs1448094 0.512 rs61930861 chr12:86245023 G/T cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC trans rs9388451 0.626 rs2875881 chr6:126072853 C/G cg05039488 chr6:79577232 IRAK1BP1 -0.66 -10.88 -0.51 6.98e-24 Brugada syndrome; LIHC cis rs16870629 0.541 rs2334955 chr5:1062444 A/G cg00278107 chr5:1061253 SLC12A7 -0.96 -18.12 -0.7 6.26e-52 QT interval; LIHC cis rs35883536 1.000 rs1610387 chr1:101123943 T/G cg14515779 chr1:101123966 NA -0.69 -13.94 -0.6 2.76e-35 Monocyte count; LIHC cis rs11792861 0.926 rs11788904 chr9:111865052 T/C cg13535736 chr9:111863775 C9orf5 -0.38 -5.73 -0.3 2.21e-8 Menarche (age at onset); LIHC cis rs9522267 0.737 rs9515448 chr13:112229526 A/T cg10483660 chr13:112241077 NA -0.25 -6.3 -0.32 9.22e-10 Hepatitis; LIHC cis rs2760061 0.626 rs635563 chr1:228136834 C/T cg02753203 chr1:228287806 NA -0.49 -7.91 -0.39 3.59e-14 Diastolic blood pressure; LIHC cis rs1008375 1.000 rs1121091 chr4:17676386 A/C cg02297831 chr4:17616191 MED28 0.42 6.73 0.34 7.12e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6933660 0.745 rs3800272 chr6:151744283 A/G cg10883421 chr6:151773342 RMND1;C6orf211 -0.55 -8.83 -0.43 5.44e-17 Menarche (age at onset); LIHC trans rs10506458 1.000 rs12425655 chr12:63434463 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.76 -10.98 -0.51 3.1e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs2153535 0.580 rs965706 chr6:8464708 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs427394 0.802 rs274721 chr5:6719164 C/T cg10857441 chr5:6722123 POLS -0.36 -6.27 -0.32 1.09e-9 Menopause (age at onset); LIHC cis rs6782228 0.565 rs2811496 chr3:128359958 A/T cg16766828 chr3:128327626 NA -0.4 -6.34 -0.32 7.21e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs2070488 1.000 rs1841777 chr3:38484819 T/C cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC cis rs4819052 0.807 rs28715237 chr21:46673768 C/G cg11663144 chr21:46675770 NA -0.32 -5.92 -0.31 7.69e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg06634786 chr22:41940651 POLR3H -0.82 -8.91 -0.43 3.12e-17 Vitiligo; LIHC cis rs933688 1.000 rs889213 chr5:90682151 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.44 0.66 3.67e-45 Smoking behavior; LIHC cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC cis rs7843479 0.601 rs10866837 chr8:21861663 G/C cg17168535 chr8:21777572 XPO7 0.55 9.58 0.46 2.04e-19 Mean corpuscular volume; LIHC cis rs9309473 0.528 rs10191517 chr2:73558403 G/A cg20560298 chr2:73613845 ALMS1 -0.46 -7.17 -0.36 4.64e-12 Metabolite levels; LIHC cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg09025071 chr16:1593152 IFT140;TMEM204 0.33 6.4 0.33 5.14e-10 Coronary artery disease; LIHC cis rs1801251 1.000 rs11555646 chr2:233599904 A/C cg08000102 chr2:233561755 GIGYF2 0.76 11.35 0.52 1.49e-25 Coronary artery disease; LIHC cis rs7408868 1.000 rs8107180 chr19:15275430 T/C cg14696996 chr19:15285081 NOTCH3 0.53 7.11 0.36 6.93e-12 Pulse pressure; LIHC cis rs7647973 1.000 rs13088309 chr3:49368317 A/G cg07636037 chr3:49044803 WDR6 0.5 6.14 0.31 2.35e-9 Menarche (age at onset); LIHC cis rs12887734 0.566 rs3742366 chr14:104198351 T/C cg01849466 chr14:104193079 ZFYVE21 -0.41 -6.13 -0.31 2.41e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs494453 0.583 rs564807 chr1:112212301 A/G cg13908074 chr2:149259371 MBD5 0.4 6.44 0.33 3.96e-10 Osteoporosis-related phenotypes; LIHC cis rs7789940 0.951 rs73140055 chr7:75975777 A/T cg10167463 chr7:75959203 YWHAG -0.45 -7.06 -0.36 9.61e-12 Multiple sclerosis; LIHC cis rs3859192 0.599 rs2302777 chr17:38179492 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.81 16.6 0.67 8.41e-46 White blood cell count; LIHC cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs2303759 0.709 rs10422677 chr19:49824290 C/T cg22307029 chr19:49891270 CCDC155 0.56 8.62 0.42 2.52e-16 Multiple sclerosis; LIHC cis rs34779708 0.966 rs4934735 chr10:35496730 C/T cg04310649 chr10:35416472 CREM 0.42 5.81 0.3 1.41e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12701220 0.901 rs12701708 chr7:1090333 C/T cg18765753 chr7:1198926 ZFAND2A -0.4 -5.79 -0.3 1.63e-8 Bronchopulmonary dysplasia; LIHC cis rs2408955 0.521 rs10875749 chr12:48531917 T/A cg21466736 chr12:48725269 NA 0.62 8.99 0.44 1.67e-17 Glycated hemoglobin levels; LIHC cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.93 -0.31 7.3e-9 Colorectal cancer; LIHC cis rs17401966 0.838 rs4846197 chr1:10282166 G/A cg19773385 chr1:10388646 KIF1B -0.38 -6.92 -0.35 2.28e-11 Hepatocellular carcinoma; LIHC cis rs17401966 0.838 rs4333852 chr1:10387704 A/T cg19773385 chr1:10388646 KIF1B 0.4 7.19 0.36 4.14e-12 Hepatocellular carcinoma; LIHC trans rs61931739 0.517 rs7960878 chr12:34055645 C/A cg26384229 chr12:38710491 ALG10B 0.51 7.07 0.36 8.59e-12 Morning vs. evening chronotype; LIHC cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.96 9.12 0.44 6.46e-18 Platelet count; LIHC cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg01765077 chr12:122356316 WDR66 0.56 7.68 0.38 1.7e-13 Mean corpuscular volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21219744 chr4:44680344 GUF1 0.4 6.18 0.32 1.83e-9 Cognitive function; LIHC cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg13395646 chr4:1353034 KIAA1530 0.55 9.24 0.45 2.6e-18 Obesity-related traits; LIHC cis rs4803468 1.000 rs10853751 chr19:41903220 G/A cg14132834 chr19:41945861 ATP5SL -0.43 -6.49 -0.33 3.04e-10 Height; LIHC trans rs1005277 0.522 rs1208767 chr10:38042295 G/T cg17830980 chr10:43048298 ZNF37B -0.44 -8.42 -0.41 1.03e-15 Extrinsic epigenetic age acceleration; LIHC cis rs16828019 0.777 rs12739052 chr1:41464455 C/A cg03387723 chr1:41708464 SCMH1 -0.45 -6.66 -0.34 1.07e-10 Intelligence (multi-trait analysis); LIHC cis rs1499614 1.000 rs2707838 chr7:66159201 C/T cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs9430161 0.564 rs12081176 chr1:11034145 T/C cg27631724 chr1:11040367 C1orf127 0.37 6.83 0.35 4.01e-11 Ewing sarcoma; LIHC cis rs6545883 0.929 rs778154 chr2:61646631 T/C cg15711740 chr2:61764176 XPO1 0.43 6.08 0.31 3.29e-9 Tuberculosis; LIHC cis rs5769765 0.704 rs138837 chr22:50180714 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.54 -6.6 -0.34 1.56e-10 Schizophrenia; LIHC cis rs9818758 0.607 rs9862483 chr3:49195441 G/A cg07636037 chr3:49044803 WDR6 -0.79 -8.36 -0.41 1.6e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2842992 0.789 rs4276525 chr6:160193612 G/A cg11366901 chr6:160182831 ACAT2 0.92 15.43 0.64 3.78e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs10744422 0.748 rs1671688 chr12:123255733 A/T cg25930673 chr12:123319894 HIP1R -0.81 -10.13 -0.48 2.8e-21 Schizophrenia; LIHC cis rs3806843 0.832 rs2531360 chr5:140116664 G/A cg19875535 chr5:140030758 IK -0.37 -6.07 -0.31 3.43e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2404602 0.679 rs12899871 chr15:76757347 T/C cg03037974 chr15:76606532 NA 0.8 16.45 0.66 3.41e-45 Blood metabolite levels; LIHC trans rs877282 0.583 rs10904566 chr10:821662 C/G cg22713356 chr15:30763199 NA 0.85 7.21 0.36 3.56e-12 Uric acid levels; LIHC cis rs7412746 0.658 rs11582281 chr1:150826831 T/C cg17724175 chr1:150552817 MCL1 0.47 9.07 0.44 9.86e-18 Melanoma; LIHC cis rs7772486 0.875 rs2748483 chr6:146335560 A/T cg05347473 chr6:146136440 FBXO30 -0.36 -6.02 -0.31 4.61e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3106136 0.681 rs11097422 chr4:95302982 C/G cg11021082 chr4:95130006 SMARCAD1 0.34 5.85 0.3 1.14e-8 Capecitabine sensitivity; LIHC cis rs526821 0.595 rs485555 chr11:55323570 A/G cg04317927 chr11:55418816 OR4S2 -0.47 -9.01 -0.44 1.43e-17 Pediatric bone mineral density (spine); LIHC cis rs360798 0.512 rs12989754 chr2:63020970 A/G cg17519650 chr2:63277830 OTX1 -0.54 -8.3 -0.41 2.44e-15 Coronary artery disease; LIHC cis rs929354 0.685 rs1808217 chr7:157002741 T/C cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.9e-9 Body mass index; LIHC cis rs208515 0.525 rs10944859 chr6:66665197 A/G cg07460842 chr6:66804631 NA 0.78 8.89 0.43 3.7e-17 Exhaled nitric oxide levels; LIHC cis rs4925386 0.921 rs11204472 chr20:60920887 G/A cg06026331 chr20:60912101 LAMA5 -0.52 -8.8 -0.43 7.1e-17 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7098414 0.530 rs10749572 chr10:82136664 G/T cg00277334 chr10:82204260 NA -0.59 -9.32 -0.45 1.48e-18 Post bronchodilator FEV1; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg04296903 chr1:1203256 UBE2J2 0.39 6.52 0.33 2.54e-10 Oropharynx cancer; LIHC cis rs5769765 0.913 rs8135071 chr22:50299587 T/C cg26441486 chr22:50317300 CRELD2 0.35 6.22 0.32 1.45e-9 Schizophrenia; LIHC cis rs11621710 0.557 rs799474 chr14:35516099 C/G cg16230307 chr14:35515116 FAM177A1 0.48 8.55 0.42 4.2e-16 Granulocyte percentage of myeloid white cells; LIHC trans rs4843747 0.641 rs11117353 chr16:88090895 A/G cg26811252 chr16:29126840 RRN3P2 0.47 7.81 0.39 7.12e-14 Menopause (age at onset); LIHC cis rs3892630 0.529 rs35300319 chr19:33409948 G/A cg22980127 chr19:33182716 NUDT19 0.72 8.36 0.41 1.62e-15 Red blood cell traits; LIHC cis rs11758351 0.518 rs79922979 chr6:26224975 A/G cg03854865 chr6:26224070 HIST1H3E 0.59 6.43 0.33 4.33e-10 Gout;Renal underexcretion gout; LIHC cis rs10540 1.000 rs61876340 chr11:495699 A/C cg03576123 chr11:487126 PTDSS2 -1.16 -8.65 -0.42 2.07e-16 Body mass index; LIHC cis rs6088580 0.524 rs6088565 chr20:33254986 A/C cg07148914 chr20:33460835 GGT7 -0.52 -7.3 -0.37 2.03e-12 Glomerular filtration rate (creatinine); LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg04234412 chr22:24373322 LOC391322 -0.74 -11.35 -0.52 1.43e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs477895 1.000 rs2286614 chr11:64068310 C/T cg18225595 chr11:63971243 STIP1 0.64 6.43 0.33 4.37e-10 Mean platelet volume; LIHC cis rs2153535 0.580 rs9378551 chr6:8463744 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.31 0.55 4.43e-29 Motion sickness; LIHC cis rs921968 0.541 rs12619347 chr2:219419935 T/C cg02985541 chr2:219472218 PLCD4 -0.42 -6.86 -0.35 3.26e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg05564831 chr3:52568323 NT5DC2 0.35 5.89 0.3 9.07e-9 Electroencephalogram traits; LIHC cis rs8056893 0.714 rs6499173 chr16:68388115 G/A cg02226672 chr16:68398533 SMPD3 0.44 6.31 0.32 8.55e-10 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs6089584 0.888 rs6061405 chr20:60617033 A/G cg06108461 chr20:60628389 TAF4 -0.99 -17.11 -0.68 7.32e-48 Body mass index; LIHC cis rs4423214 0.592 rs78300366 chr11:71205514 A/G cg05163923 chr11:71159392 DHCR7 -0.58 -7.01 -0.35 1.24e-11 Vitamin D levels; LIHC cis rs35146811 0.844 rs4424195 chr7:99642745 A/G cg22906224 chr7:99728672 NA 0.41 5.87 0.3 1.01e-8 Coronary artery disease; LIHC trans rs7849581 1 rs7849581 chr9:9924724 A/G cg15290081 chr7:76254647 POMZP3;LOC100133091 0.57 6.67 0.34 1.02e-10 Myopia (pathological); LIHC cis rs10847980 0.590 rs12299742 chr12:123323357 T/G cg18912006 chr12:123335444 HIP1R 0.72 7.44 0.37 8.06e-13 Adiponectin levels; LIHC cis rs11864453 0.826 rs12325142 chr16:72138112 G/T cg01557791 chr16:72042693 DHODH -0.52 -8.53 -0.42 4.8e-16 Fibrinogen levels; LIHC cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12830829 chr14:51707081 TMX1 -0.53 -8.02 -0.4 1.7e-14 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs919433 0.617 rs700645 chr2:198605514 A/G cg10820045 chr2:198174542 NA 0.5 7.55 0.38 3.91e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2235642 0.691 rs2281235 chr16:1603535 T/C cg03034668 chr16:1723424 CRAMP1L -0.41 -7.27 -0.37 2.47e-12 Coronary artery disease; LIHC cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg03264133 chr6:25882463 NA -0.39 -6.08 -0.31 3.27e-9 Height; LIHC cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg26939375 chr7:64535504 NA 0.47 7.15 0.36 5.18e-12 Aortic root size; LIHC cis rs9902453 0.967 rs4994355 chr17:28386284 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs6502050 0.835 rs67682841 chr17:80117745 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs12701220 0.696 rs12112029 chr7:1137889 G/A cg18765753 chr7:1198926 ZFAND2A -0.43 -6.15 -0.32 2.22e-9 Bronchopulmonary dysplasia; LIHC cis rs10504229 0.679 rs12375285 chr8:58040084 G/A cg02290350 chr8:58132656 NA 0.33 7.25 0.36 2.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs9640161 0.742 rs2159236 chr7:150017214 A/G cg10018233 chr7:150070692 REPIN1 0.53 8.97 0.44 2.01e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs8077889 0.917 rs58080788 chr17:41902909 A/G cg26893861 chr17:41843967 DUSP3 0.93 10.72 0.5 2.51e-23 Triglycerides; LIHC cis rs4690686 0.964 rs1840270 chr4:177246288 G/C cg17059388 chr4:177262070 NA 0.38 6.93 0.35 2.1e-11 Essential tremor; LIHC cis rs9311474 0.607 rs4475032 chr3:52560021 C/T cg18404041 chr3:52824283 ITIH1 -0.48 -7.56 -0.38 3.76e-13 Electroencephalogram traits; LIHC cis rs9309711 0.666 rs11127429 chr2:3485224 T/G cg15506890 chr2:3487001 NA -0.48 -7.66 -0.38 1.92e-13 Neurofibrillary tangles; LIHC trans rs4927850 1.000 rs6799572 chr3:195740408 C/T cg21051086 chr3:73046214 PPP4R2 -0.39 -6.22 -0.32 1.44e-9 Pancreatic cancer; LIHC cis rs1865760 1.000 rs9348698 chr6:25929689 T/A cg03517284 chr6:25882590 NA -0.39 -5.81 -0.3 1.44e-8 Height; LIHC cis rs4150161 0.656 rs2288026 chr16:84220344 C/G cg10106505 chr16:84220380 TAF1C 0.86 8.75 0.43 1e-16 Systolic blood pressure response to hydrochlorothiazide in hypertension; LIHC cis rs722599 0.715 rs61978928 chr14:75321714 T/C cg08847533 chr14:75593920 NEK9 -0.51 -7.81 -0.39 7.14e-14 IgG glycosylation; LIHC cis rs240764 0.817 rs239189 chr6:101128787 C/T cg09795085 chr6:101329169 ASCC3 0.52 7.13 0.36 6.12e-12 Neuroticism; LIHC cis rs10870270 1.000 rs4880250 chr10:133773919 G/A cg26149184 chr10:133730230 NA 0.47 7.5 0.38 5.69e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10791097 0.667 rs4937584 chr11:130741761 A/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg02475777 chr4:1388615 CRIPAK 0.54 8.14 0.4 7.27e-15 Longevity; LIHC cis rs5769765 0.542 rs5769751 chr22:50242733 T/G cg02269571 chr22:50332266 NA 1.14 9.55 0.46 2.6e-19 Schizophrenia; LIHC cis rs8062405 1.000 rs72793812 chr16:28840381 A/G cg00204512 chr16:28754710 NA 0.37 6.63 0.34 1.33e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg18305652 chr10:134549665 INPP5A 0.49 7.85 0.39 5.58e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9611565 0.512 rs4822052 chr22:42193741 G/A cg03806693 chr22:41940476 POLR3H -0.83 -9.22 -0.45 3.15e-18 Vitiligo; LIHC cis rs2180341 0.814 rs9401958 chr6:127736357 T/G cg24812749 chr6:127587940 RNF146 0.8 12.66 0.56 2.11e-30 Breast cancer; LIHC cis rs11626933 1.000 rs11626016 chr14:90747979 C/T cg04374321 chr14:90722782 PSMC1 0.47 6.5 0.33 2.85e-10 Gut microbiota (bacterial taxa); LIHC cis rs17401966 0.838 rs4623 chr1:10366692 C/G cg15208524 chr1:10270712 KIF1B 0.38 5.87 0.3 1.04e-8 Hepatocellular carcinoma; LIHC cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg12373951 chr3:133503437 NA 0.46 7.65 0.38 2.03e-13 Iron status biomarkers; LIHC trans rs1814175 0.817 rs1794162 chr11:49899506 A/C cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs7582720 1.000 rs77931721 chr2:203763076 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs11098499 0.570 rs6832740 chr4:120546136 T/C cg09307838 chr4:120376055 NA 0.67 10.34 0.49 5.7e-22 Corneal astigmatism; LIHC cis rs4407350 0.756 rs131168 chr22:44896225 T/C cg11695653 chr22:44894386 LDOC1L -0.37 -6.46 -0.33 3.68e-10 Intelligence (multi-trait analysis); LIHC cis rs12926788 0.689 rs1862450 chr16:24856775 A/G cg04756594 chr16:24857601 SLC5A11 -0.47 -6.51 -0.33 2.64e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs911119 0.866 rs2405393 chr20:23569392 G/C cg16589663 chr20:23618590 CST3 0.65 6.74 0.34 6.57e-11 Chronic kidney disease; LIHC cis rs2282802 0.685 rs6580473 chr5:139646962 C/T cg26211634 chr5:139558579 C5orf32 -0.38 -5.85 -0.3 1.15e-8 Intelligence (multi-trait analysis); LIHC cis rs7267979 1.000 rs7018 chr20:25278261 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.77 0.34 5.65e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs17685 0.725 rs1044483 chr7:75659815 T/C cg01364799 chr7:75623366 TMEM120A 0.48 7.36 0.37 1.36e-12 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs6489882 0.867 rs1859335 chr12:113367325 C/T cg10175203 chr3:128143634 NA 0.38 6.12 0.31 2.6e-9 Chronic lymphocytic leukemia; LIHC cis rs9549367 0.789 rs2302757 chr13:113909339 A/G cg18105134 chr13:113819100 PROZ -0.67 -11.47 -0.53 5.57e-26 Platelet distribution width; LIHC cis rs56235845 0.694 rs6875461 chr5:176754665 C/T cg17509989 chr5:176798049 RGS14 -0.61 -7.92 -0.39 3.4e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs7772486 0.875 rs2777481 chr6:146310036 G/T cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.95e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs782590 0.902 rs782600 chr2:55848040 T/C cg18811423 chr2:55921094 PNPT1 0.95 14.93 0.63 3.78e-39 Metabolic syndrome; LIHC cis rs4788570 0.697 rs2173702 chr16:71812671 G/A cg06353428 chr16:71660113 MARVELD3 1.34 13.32 0.58 6.95e-33 Intelligence (multi-trait analysis); LIHC cis rs11124272 0.761 rs4952244 chr2:32036625 G/A cg02381751 chr2:32503542 YIPF4 -0.42 -5.78 -0.3 1.71e-8 Interleukin-18 levels; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.28 0.55 6e-29 Prudent dietary pattern; LIHC cis rs7618501 0.519 rs3774750 chr3:50208406 C/G cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.53 -7.76 -0.39 9.99e-14 Intelligence (multi-trait analysis); LIHC cis rs6831352 0.760 rs2602859 chr4:100030583 G/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Alcohol dependence; LIHC cis rs9470366 0.545 rs2395655 chr6:36645696 C/T cg00935119 chr6:36647544 CDKN1A 0.41 5.94 0.31 6.85e-9 QRS duration; LIHC cis rs881375 0.678 rs9886724 chr9:123665019 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.64 0.34 1.2e-10 Rheumatoid arthritis; LIHC cis rs4718428 0.960 rs6460317 chr7:66390255 A/G cg18252515 chr7:66147081 NA -0.52 -6.38 -0.33 5.61e-10 Corneal structure; LIHC cis rs60733400 0.500 rs72644697 chr1:2533605 G/A cg18854424 chr1:2615690 NA 0.33 7.12 0.36 6.46e-12 Multiple sclerosis; LIHC cis rs9399135 0.660 rs9389248 chr6:135282656 T/C cg22676075 chr6:135203613 NA 0.39 6.44 0.33 4.09e-10 Red blood cell count; LIHC cis rs9303401 0.659 rs11079358 chr17:56920949 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.58 0.59 6.99e-34 Cognitive test performance; LIHC cis rs17286411 0.671 rs2036338 chr16:71788830 C/G cg06353428 chr16:71660113 MARVELD3 -0.44 -6.52 -0.33 2.49e-10 Blood protein levels; LIHC cis rs2108622 0.647 rs111427692 chr19:15977479 A/T cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.81e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs2153535 0.563 rs7739249 chr6:8534590 C/G cg07606381 chr6:8435919 SLC35B3 0.79 11.98 0.54 7.28e-28 Motion sickness; LIHC cis rs17106184 1.000 rs72898951 chr1:50963518 G/C cg07174182 chr1:51127561 FAF1 -0.59 -6.66 -0.34 1.07e-10 Type 2 diabetes; LIHC cis rs8114671 0.836 rs4911461 chr20:33629993 A/C cg07148914 chr20:33460835 GGT7 -0.56 -8.44 -0.42 9.31e-16 Height; LIHC cis rs7772486 0.875 rs7766463 chr6:146364453 A/G cg23711669 chr6:146136114 FBXO30 0.6 10.62 0.5 5.92e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg11494091 chr17:61959527 GH2 0.35 5.79 0.3 1.58e-8 Height; LIHC trans rs6952808 0.595 rs3778984 chr7:2166514 T/C cg04565464 chr8:145669602 NFKBIL2 0.37 6.19 0.32 1.76e-9 Bipolar disorder and schizophrenia; LIHC cis rs12464559 0.522 rs7424335 chr2:152593741 C/T cg01189475 chr2:152685088 ARL5A 0.74 9.21 0.45 3.25e-18 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs1577917 0.681 rs4348284 chr6:86350394 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.43 -0.41 1e-15 Response to antipsychotic treatment; LIHC cis rs2439831 0.867 rs2412778 chr15:43660982 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.88 0.67 6.27e-47 Lung cancer in ever smokers; LIHC cis rs950169 0.580 rs11633762 chr15:85187152 T/C cg17507749 chr15:85114479 UBE2QP1 0.66 7.3 0.37 1.97e-12 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07071157 chr11:72525331 ATG16L2 -0.45 -6.06 -0.31 3.55e-9 Pancreatic cancer; LIHC trans rs60843830 1.000 rs17713729 chr2:249092 A/C cg11347411 chr7:150020925 ACTR3C;LRRC61 0.64 9.25 0.45 2.5e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs1670533 1.000 rs6599278 chr4:1058798 C/T cg27284194 chr4:1044797 NA 0.56 8.17 0.4 5.88e-15 Recombination rate (females); LIHC cis rs2204008 0.665 rs11179830 chr12:38220966 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.56 0.5 9.48e-23 Bladder cancer; LIHC cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.53e-9 Menopause (age at onset); LIHC cis rs10503871 0.625 rs13250304 chr8:30346587 G/A cg26383811 chr8:30366931 RBPMS 0.43 7.48 0.37 6.46e-13 Metabolite levels (X-11787); LIHC cis rs116095464 0.558 rs114607464 chr5:300468 C/T cg22857025 chr5:266934 NA -1.45 -16.93 -0.68 4.11e-47 Breast cancer; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg16249105 chr10:120938029 PRDX3 -0.39 -6.07 -0.31 3.38e-9 Bilirubin levels; LIHC cis rs10751667 1.000 rs6597965 chr11:964476 A/G cg06064525 chr11:970664 AP2A2 -0.5 -12.47 -0.56 1.14e-29 Alzheimer's disease (late onset); LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg09455208 chr3:40491958 NA 0.39 7.91 0.39 3.5e-14 Renal cell carcinoma; LIHC cis rs10927875 0.632 rs10927864 chr1:16165661 C/G cg21385522 chr1:16154831 NA -1.04 -17.29 -0.68 1.35e-48 Dilated cardiomyopathy; LIHC cis rs116248771 0.690 rs16829314 chr3:158416409 C/T cg16708174 chr3:158430962 RARRES1 0.46 6.13 0.31 2.45e-9 diarrhoeal disease at age 2; LIHC cis rs1799949 0.773 rs2137990 chr17:41317896 T/A cg25072359 chr17:41440525 NA -0.37 -5.9 -0.3 8.74e-9 Menopause (age at onset); LIHC cis rs782590 0.764 rs2586969 chr2:55829392 G/C cg18811423 chr2:55921094 PNPT1 0.79 11.65 0.53 1.22e-26 Metabolic syndrome; LIHC cis rs7552404 1.000 rs9662166 chr1:76235906 C/A cg10523679 chr1:76189770 ACADM 0.65 8.69 0.43 1.56e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6582630 0.638 rs12424222 chr12:38548273 C/T cg26384229 chr12:38710491 ALG10B -0.48 -6.76 -0.34 6.1e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs2303745 0.589 rs6512182 chr19:17399476 G/T cg02221750 chr19:17393354 ANKLE1 -0.41 -5.8 -0.3 1.53e-8 Systemic lupus erythematosus; LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg02990361 chr1:107599529 PRMT6 0.64 10.78 0.5 1.64e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9303401 0.614 rs66480139 chr17:57101538 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.81 0.54 3.03e-27 Cognitive test performance; LIHC cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.83 0.35 3.8e-11 Gut microbiome composition (summer); LIHC cis rs5769707 0.542 rs739242 chr22:50057116 A/G cg01652190 chr22:50026171 C22orf34 -0.29 -6.34 -0.32 7.24e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1997103 0.906 rs4618644 chr7:55402037 T/G cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6952808 0.825 rs4236277 chr7:1942270 C/T cg04267008 chr7:1944627 MAD1L1 -0.72 -11.35 -0.52 1.43e-25 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.7 11.29 0.52 2.49e-25 Prudent dietary pattern; LIHC cis rs12477438 0.798 rs6712338 chr2:99585457 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.71 -0.65 3.04e-42 Chronic sinus infection; LIHC cis rs7103648 0.897 rs11606287 chr11:47407439 C/A cg20307385 chr11:47447363 PSMC3 0.86 12.49 0.56 9.45e-30 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs11969893 0.850 rs9404055 chr6:101302260 C/T cg12253828 chr6:101329408 ASCC3 1.08 13.8 0.6 9.47e-35 Economic and political preferences (immigration/crime); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg23671189 chr11:68830561 TPCN2 0.4 6.15 0.32 2.15e-9 Bilirubin levels; LIHC cis rs9486719 1.000 rs2205755 chr6:96864704 A/G cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs9457247 0.602 rs9457262 chr6:167473685 A/G cg12798992 chr6:167411361 FGFR1OP 0.47 6.94 0.35 2.04e-11 Crohn's disease; LIHC cis rs1552244 0.882 rs112621205 chr3:10017916 G/A cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.14e-11 Alzheimer's disease; LIHC cis rs611744 0.647 rs674391 chr8:109242803 A/T cg18478394 chr8:109455254 TTC35 0.42 7.34 0.37 1.54e-12 Dupuytren's disease; LIHC cis rs894734 0.535 rs2366144 chr12:54324069 G/T cg12374095 chr12:54320830 NA 0.45 6.95 0.35 1.81e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs904251 0.600 rs12211110 chr6:37466232 A/G cg01843034 chr6:37503916 NA -0.41 -6.75 -0.34 6.5e-11 Cognitive performance; LIHC cis rs7619427 0.908 rs7653170 chr3:44076195 T/A cg24966902 chr3:44043705 NA 0.5 7.05 0.36 9.76e-12 Schizophrenia; LIHC cis rs10197940 0.662 rs4335940 chr2:152275304 A/G cg06191203 chr2:152266755 RIF1 0.45 7.71 0.38 1.35e-13 Lung cancer; LIHC cis rs1577917 1.000 rs1911553 chr6:86630892 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs6960043 0.782 rs10228456 chr7:15063926 C/T cg19272540 chr7:15055459 NA -0.24 -6.44 -0.33 3.97e-10 Type 2 diabetes; LIHC cis rs1865721 0.771 rs7236311 chr18:73137450 A/G cg26385618 chr18:73139727 C18orf62 -0.31 -8.64 -0.42 2.13e-16 Intelligence; LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg00800038 chr16:89945340 TCF25 -0.6 -9.53 -0.46 3.02e-19 Skin colour saturation; LIHC cis rs4845570 1.000 rs11586946 chr1:151769806 G/A cg07092448 chr1:151763213 TDRKH -0.67 -6.96 -0.35 1.79e-11 Coronary artery disease; LIHC cis rs67311347 0.956 rs11714871 chr3:40428938 T/G cg16822855 chr3:40428330 ENTPD3 0.34 6.27 0.32 1.11e-9 Renal cell carcinoma; LIHC cis rs798554 0.721 rs2527680 chr7:2892361 C/T cg13628971 chr7:2884303 GNA12 0.6 10.15 0.48 2.46e-21 Height; LIHC cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.3 0.37 1.99e-12 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg09904177 chr6:26538194 HMGN4 0.57 11.21 0.52 4.9e-25 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.563 rs2505215 chr10:38481273 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.27 -0.32 1.06e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg22105103 chr4:187893119 NA -0.33 -8.22 -0.41 4.27e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs903552 1.000 rs34937195 chr15:102003631 C/A cg19295451 chr15:102010161 PCSK6 -0.44 -6.17 -0.32 1.97e-9 Diabetic kidney disease; LIHC cis rs4843747 0.671 rs9933794 chr16:88116981 T/C cg07560587 chr16:88016574 BANP 0.38 5.98 0.31 5.55e-9 Menopause (age at onset); LIHC cis rs12220238 0.915 rs7073139 chr10:76071189 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg21724239 chr8:58056113 NA 0.58 7.69 0.38 1.63e-13 Developmental language disorder (linguistic errors); LIHC cis rs908922 0.676 rs1856119 chr1:152512483 A/G cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC trans rs1973993 0.689 rs17131755 chr1:96886167 G/A cg10631902 chr5:14652156 NA -0.3 -6.42 -0.33 4.43e-10 Weight; LIHC cis rs1401999 1.000 rs4148575 chr3:183702275 A/G cg05044414 chr3:183734942 ABCC5 0.33 5.91 0.3 8.1e-9 Anterior chamber depth; LIHC cis rs11628318 0.564 rs8006489 chr14:103121232 G/A cg12046867 chr14:103022105 NA 0.39 5.92 0.3 7.76e-9 Platelet count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26875902 chr16:2223324 TRAF7 -0.39 -6.4 -0.33 5.01e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg03264133 chr6:25882463 NA -0.62 -8.73 -0.43 1.12e-16 Blood metabolite levels; LIHC cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs4665809 0.816 rs2384359 chr2:26371364 T/C cg25036284 chr2:26402008 FAM59B -0.51 -5.78 -0.3 1.69e-8 Gut microbiome composition (summer); LIHC cis rs3892630 0.588 rs28787932 chr19:33226229 T/C cg22980127 chr19:33182716 NUDT19 1.05 13.69 0.6 2.46e-34 Red blood cell traits; LIHC cis rs2180341 0.920 rs1073931 chr6:127681762 A/T cg24812749 chr6:127587940 RNF146 1.04 15.25 0.64 2.08e-40 Breast cancer; LIHC cis rs597539 0.652 rs584108 chr11:68630282 A/T cg06028808 chr11:68637592 NA -0.45 -5.91 -0.3 8.33e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs7615952 0.866 rs1976459 chr3:125647486 A/T cg07211511 chr3:129823064 LOC729375 -0.84 -10.43 -0.49 2.67e-22 Blood pressure (smoking interaction); LIHC cis rs875971 0.862 rs4718383 chr7:66108409 T/C cg18252515 chr7:66147081 NA 0.48 7.05 0.36 9.79e-12 Aortic root size; LIHC cis rs1707322 0.691 rs61784799 chr1:46177748 A/G cg03146154 chr1:46216737 IPP -0.58 -9.48 -0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 0.572 rs73117481 chr3:10160132 C/T cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs3812831 0.695 rs7983872 chr13:114944781 T/G cg08824895 chr13:115047677 UPF3A 0.5 7.26 0.37 2.59e-12 Schizophrenia; LIHC cis rs11711311 1.000 rs9828099 chr3:113518402 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.84 -0.35 3.74e-11 IgG glycosylation; LIHC cis rs4665809 0.818 rs35413760 chr2:26267137 C/A cg27170947 chr2:26402098 FAM59B 0.58 6.25 0.32 1.21e-9 Gut microbiome composition (summer); LIHC trans rs1814175 0.587 rs847628 chr11:49927064 A/T cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs10416265 0.516 rs1270252 chr19:33623604 G/A cg17764715 chr19:33622953 WDR88 -0.51 -6.77 -0.34 5.76e-11 Bone properties (heel); LIHC cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg06481639 chr22:41940642 POLR3H 0.71 7.17 0.36 4.8e-12 Vitiligo; LIHC trans rs6489882 0.867 rs6489877 chr12:113368079 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs7072216 0.655 rs3830025 chr10:100176104 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.06 -0.31 3.56e-9 Metabolite levels; LIHC cis rs858239 0.601 rs11982002 chr7:23163270 C/T cg23682824 chr7:23144976 KLHL7 0.41 6.16 0.32 2.07e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs6500602 0.653 rs4786487 chr16:4440397 C/G cg08645402 chr16:4508243 NA -0.36 -6.11 -0.31 2.71e-9 Schizophrenia; LIHC cis rs921968 0.541 rs6710383 chr2:219359685 T/G cg02985541 chr2:219472218 PLCD4 0.43 6.95 0.35 1.84e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6456156 0.792 rs10946214 chr6:167516122 G/A cg07741184 chr6:167504864 NA 0.26 6.23 0.32 1.35e-9 Primary biliary cholangitis; LIHC cis rs6733011 0.530 rs7608889 chr2:99481350 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.42 -6.1 -0.31 2.9e-9 Bipolar disorder; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15136424 chr2:173989197 ZAK -0.29 -6.26 -0.32 1.12e-9 Calcium levels; LIHC cis rs7940866 0.740 rs7131121 chr11:130806424 A/G cg12179176 chr11:130786555 SNX19 0.67 9.89 0.47 1.88e-20 Schizophrenia; LIHC cis rs9326248 1.000 rs7946257 chr11:117053165 A/G cg15534755 chr11:117069859 TAGLN 0.37 6.26 0.32 1.12e-9 Blood protein levels; LIHC cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg20887711 chr4:1340912 KIAA1530 0.48 7.47 0.37 6.71e-13 Obesity-related traits; LIHC cis rs5770917 1.000 rs115743514 chr22:51011933 T/C cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.4 -5.86 -0.3 1.08e-8 Narcolepsy; LIHC cis rs67311347 0.824 rs59922539 chr3:40337110 G/A cg09455208 chr3:40491958 NA 0.32 5.94 0.31 7.04e-9 Renal cell carcinoma; LIHC cis rs7605378 0.528 rs281791 chr2:200850402 A/G cg23649088 chr2:200775458 C2orf69 -0.58 -8.45 -0.42 8.73e-16 Osteoporosis; LIHC cis rs910316 0.967 rs175498 chr14:75536369 G/A cg11812906 chr14:75593930 NEK9 -0.77 -15.73 -0.65 2.5e-42 Height; LIHC cis rs1538970 1.000 rs4520450 chr1:45834773 A/G cg05343316 chr1:45956843 TESK2 0.57 8.55 0.42 4.32e-16 Platelet count; LIHC cis rs7027203 0.828 rs10821229 chr9:96595136 A/C cg14396892 chr9:96623032 NA -0.32 -6.21 -0.32 1.5e-9 DNA methylation (variation); LIHC cis rs9549367 0.774 rs9549364 chr13:113903745 T/C cg18105134 chr13:113819100 PROZ -0.68 -11.64 -0.53 1.29e-26 Platelet distribution width; LIHC cis rs17685 0.725 rs4728548 chr7:75654632 A/T cg16684958 chr7:75615977 POR -0.51 -8.58 -0.42 3.48e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg07061783 chr6:25882402 NA 0.69 8.76 0.43 9.54e-17 Blood metabolite levels; LIHC trans rs3858145 0.506 rs10762224 chr10:70086313 A/G cg08973675 chr10:101380289 SLC25A28 0.52 6.36 0.33 6.54e-10 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg05368731 chr17:41323189 NBR1 0.72 12.06 0.55 3.69e-28 Menopause (age at onset); LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg23375431 chr12:122242145 LOC338799;SETD1B -0.37 -6.2 -0.32 1.6e-9 Neuroblastoma; LIHC cis rs875971 0.838 rs2173570 chr7:65762963 T/A cg18252515 chr7:66147081 NA 0.42 5.89 0.3 9.22e-9 Aortic root size; LIHC trans rs6058796 0.681 rs28529295 chr20:31274668 C/G cg02600331 chr11:130417168 NA 0.37 7.71 0.38 1.37e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs921968 0.643 rs711191 chr2:219386084 T/A cg02985541 chr2:219472218 PLCD4 0.45 8.71 0.43 1.33e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs7103648 0.630 rs7120548 chr11:47662932 A/G cg20307385 chr11:47447363 PSMC3 1.01 16.48 0.67 2.61e-45 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.2 -0.32 1.63e-9 Colorectal cancer; LIHC cis rs13161895 0.713 rs76315806 chr5:179485515 C/G cg06664874 chr5:179499304 RNF130 0.66 7.56 0.38 3.69e-13 LDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22207900 chr11:64072031 ESRRA;C11orf20 0.44 6.31 0.32 8.77e-10 Lung function (FEV1/FVC); LIHC cis rs7106204 0.514 rs7118022 chr11:24253352 C/T ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.24e-27 Response to Homoharringtonine (cytotoxicity); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11579281 chr15:62352619 VPS13C -0.43 -6.13 -0.31 2.38e-9 Pancreatic cancer; LIHC trans rs4650994 0.524 rs2209170 chr1:178607388 C/A cg05059571 chr16:84539110 KIAA1609 0.4 6.74 0.34 6.7e-11 HDL cholesterol levels;HDL cholesterol; LIHC cis rs765787 0.530 rs4775834 chr15:45537511 C/T cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs2991971 0.967 rs11211130 chr1:45986852 G/C cg24296786 chr1:45957014 TESK2 0.55 8.09 0.4 1.05e-14 High light scatter reticulocyte count; LIHC cis rs7568458 0.663 rs699664 chr2:85780536 A/G cg02493740 chr2:85810744 VAMP5 0.55 9.43 0.45 6.61e-19 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9303401 0.612 rs2526370 chr17:56487636 G/C cg12560992 chr17:57184187 TRIM37 0.71 10.94 0.51 4.4e-24 Cognitive test performance; LIHC cis rs7961581 0.719 rs1620771 chr12:71592703 T/G cg05756094 chr12:71608604 NA 0.4 6.48 0.33 3.16e-10 Type 2 diabetes; LIHC cis rs1348850 0.874 rs2166558 chr2:178373652 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.89 14.23 0.61 2.11e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9393692 0.905 rs9358919 chr6:26287862 C/T cg05868516 chr6:26286170 HIST1H4H 0.44 6.64 0.34 1.24e-10 Educational attainment; LIHC cis rs6089829 0.855 rs6090205 chr20:61665269 A/G cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs5417 0.788 rs2654185 chr17:7183362 G/T cg25256661 chr17:7137939 DVL2 0.5 7.99 0.4 2.11e-14 Diastolic blood pressure; LIHC cis rs6714710 0.580 rs17489915 chr2:98420431 T/C cg26665480 chr2:98280029 ACTR1B 0.43 6.11 0.31 2.71e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs1669338 0.588 rs55959448 chr3:3204000 C/T cg16797762 chr3:3221439 CRBN -0.87 -7.6 -0.38 2.92e-13 White matter integrity; LIHC cis rs28374715 0.578 rs13313520 chr15:41629127 T/G cg18705301 chr15:41695430 NDUFAF1 -1.24 -18.37 -0.7 6.1e-53 Ulcerative colitis; LIHC cis rs473651 0.935 rs541128 chr2:239336449 A/G cg21699342 chr2:239360505 ASB1 0.37 7.26 0.37 2.65e-12 Multiple system atrophy; LIHC trans rs10213084 1.000 rs10002085 chr4:147491160 G/A cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs35883536 1.000 rs3861733 chr1:101111807 G/A cg14515779 chr1:101123966 NA -0.66 -13.17 -0.58 2.6e-32 Monocyte count; LIHC cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs28829049 0.536 rs2073106 chr1:19549343 G/C cg13387374 chr1:19411106 UBR4 0.41 6.0 0.31 5.01e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs9309473 1.000 rs1114380 chr2:73804708 A/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.5 -0.33 2.86e-10 Metabolite levels; LIHC cis rs6138458 1.000 rs11906373 chr20:24938832 A/G cg26195577 chr20:24973756 C20orf3 1.17 15.19 0.63 3.36e-40 Blood protein levels; LIHC cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg23758822 chr17:41437982 NA 0.91 16.91 0.67 4.8e-47 Menopause (age at onset); LIHC cis rs826838 0.559 rs4882276 chr12:38611994 T/C cg26384229 chr12:38710491 ALG10B 0.43 6.49 0.33 2.93e-10 Heart rate; LIHC cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg24879335 chr3:133465180 TF 0.28 6.35 0.32 6.74e-10 Iron status biomarkers; LIHC cis rs4409675 0.576 rs7536088 chr1:28234325 A/G cg23691781 chr1:28212827 C1orf38 0.31 7.2 0.36 3.83e-12 Corneal astigmatism; LIHC cis rs1957429 0.731 rs10144554 chr14:65321514 T/G cg23373153 chr14:65346875 NA 0.76 10.84 0.51 1.02e-23 Pediatric areal bone mineral density (radius); LIHC cis rs796364 1.000 rs11694369 chr2:200741720 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.7 -6.35 -0.32 6.86e-10 Schizophrenia; LIHC cis rs1691799 0.867 rs1168341 chr12:66759080 G/C cg16791601 chr12:66731901 HELB -0.54 -13.09 -0.58 5.17e-32 White blood cell count (basophil); LIHC cis rs2153535 0.580 rs1577467 chr6:8444241 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs798554 0.679 rs1636254 chr7:2885724 T/C cg04166393 chr7:2884313 GNA12 0.51 8.15 0.4 6.91e-15 Height; LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg13409248 chr3:40428643 ENTPD3 -0.49 -8.38 -0.41 1.39e-15 Renal cell carcinoma; LIHC cis rs9896933 0.832 rs77512810 chr17:80804589 C/T cg20578329 chr17:80767326 TBCD -0.69 -6.73 -0.34 7.01e-11 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg03188948 chr7:1209495 NA 0.79 6.06 0.31 3.65e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs16854884 0.632 rs4535221 chr3:143658607 A/G cg06585982 chr3:143692056 C3orf58 0.58 7.72 0.39 1.27e-13 Economic and political preferences (feminism/equality); LIHC cis rs2710642 0.962 rs4671051 chr2:63032696 A/T cg17519650 chr2:63277830 OTX1 -0.44 -6.82 -0.35 4.18e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1577917 0.958 rs1545376 chr6:86504582 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.43 8.03 0.4 1.58e-14 Response to antipsychotic treatment; LIHC cis rs11122272 0.735 rs2474631 chr1:231541341 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.62 -0.5 5.71e-23 Hemoglobin concentration; LIHC cis rs16944613 0.510 rs8026218 chr15:91145265 C/T cg26821196 chr15:91095069 CRTC3 0.3 5.78 0.3 1.66e-8 Colorectal cancer; LIHC cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg22800045 chr5:56110881 MAP3K1 0.66 8.66 0.42 1.91e-16 Initial pursuit acceleration; LIHC cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg08392591 chr16:89556376 ANKRD11 0.41 6.18 0.32 1.86e-9 Multiple myeloma (IgH translocation); LIHC cis rs2842992 0.830 rs2025189 chr6:160137518 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.25 0.55 7.54e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs11971779 0.680 rs4732370 chr7:139077240 A/C cg07862535 chr7:139043722 LUC7L2 -0.58 -9.91 -0.47 1.57e-20 Diisocyanate-induced asthma; LIHC trans rs11098499 0.863 rs10009626 chr4:120470005 T/C cg25214090 chr10:38739885 LOC399744 0.59 9.52 0.46 3.25e-19 Corneal astigmatism; LIHC cis rs67460515 0.563 rs1599388 chr3:160846866 A/G cg03342759 chr3:160939853 NMD3 -0.62 -9.13 -0.44 6.11e-18 Parkinson's disease; LIHC trans rs3749237 0.964 rs35210174 chr3:49812606 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.66 10.21 0.48 1.51e-21 Resting heart rate; LIHC cis rs9814567 1.000 rs6785027 chr3:134211649 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.63 0.56 2.8e-30 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg05896524 chr21:47604654 C21orf56 0.49 7.57 0.38 3.56e-13 Testicular germ cell tumor; LIHC cis rs921968 0.613 rs6436066 chr2:219578361 T/G cg02985541 chr2:219472218 PLCD4 -0.36 -6.05 -0.31 3.83e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs6442522 0.606 rs2345105 chr3:15495764 G/A cg16303742 chr3:15540471 COLQ 0.39 6.39 0.33 5.38e-10 Uric acid levels; LIHC cis rs7395581 0.959 rs35879051 chr11:47275882 C/G cg26139080 chr11:47293733 MADD -0.5 -8.53 -0.42 4.94e-16 HDL cholesterol; LIHC cis rs735396 0.731 rs1182933 chr12:121454622 C/T cg02403541 chr12:121454288 C12orf43 0.52 9.18 0.44 4.24e-18 N-glycan levels; LIHC cis rs738321 0.757 rs9622732 chr22:38524149 G/C cg25457927 chr22:38595422 NA -0.33 -7.54 -0.38 4.2e-13 Breast cancer; LIHC cis rs7071206 0.740 rs2048781 chr10:79422975 T/C cg07817648 chr10:79422355 NA -0.31 -6.68 -0.34 9.75e-11 Bone mineral density; LIHC cis rs1401999 0.714 rs7646621 chr3:183640865 A/C cg05044414 chr3:183734942 ABCC5 -0.33 -6.26 -0.32 1.12e-9 Anterior chamber depth; LIHC cis rs7654585 0.962 rs2309289 chr4:25947094 T/A cg10409131 chr4:25915609 C4orf52 0.47 7.3 0.37 2.02e-12 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05896465 chr22:45560692 NUP50 0.48 6.88 0.35 2.87e-11 Pancreatic cancer; LIHC cis rs10752881 1.000 rs4233192 chr1:182970837 A/C ch.1.3577855R chr1:183094577 LAMC1 -0.6 -10.65 -0.5 4.59e-23 Colorectal cancer; LIHC cis rs3815700 1.000 rs2287670 chr19:33095057 G/A cg02997394 chr19:33096574 ANKRD27 0.73 9.38 0.45 9.34e-19 Eosinophilic esophagitis; LIHC cis rs67478160 0.643 rs11624184 chr14:104240998 A/G cg01849466 chr14:104193079 ZFYVE21 -0.45 -6.82 -0.35 4.15e-11 Schizophrenia; LIHC cis rs4906332 0.966 rs2065016 chr14:103879656 T/A cg26031613 chr14:104095156 KLC1 -0.4 -5.72 -0.3 2.31e-8 Coronary artery disease; LIHC cis rs9649465 1.000 rs3807634 chr7:123382290 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.19 -0.41 5.09e-15 Migraine; LIHC cis rs2070488 0.965 rs2284820 chr3:38562579 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.35 -0.61 6.8e-37 Electrocardiographic conduction measures; LIHC cis rs6089584 0.566 rs3787422 chr20:60555346 G/A cg06108461 chr20:60628389 TAF4 -0.52 -6.83 -0.35 3.84e-11 Body mass index; LIHC trans rs61931739 0.517 rs1817760 chr12:34106060 A/G cg26384229 chr12:38710491 ALG10B 0.53 7.32 0.37 1.74e-12 Morning vs. evening chronotype; LIHC cis rs1348850 0.608 rs2364845 chr2:178226240 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.82 12.96 0.57 1.6e-31 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1577917 0.958 rs12203457 chr6:86689277 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.77 -0.47 4.66e-20 Response to antipsychotic treatment; LIHC cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs9640161 0.750 rs11764936 chr7:150025915 G/T cg27494647 chr7:150038898 RARRES2 0.31 5.76 0.3 1.91e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs1538970 0.962 rs4660301 chr1:45820149 T/A cg24296786 chr1:45957014 TESK2 -0.49 -7.33 -0.37 1.71e-12 Platelet count; LIHC cis rs7249142 0.549 rs2238667 chr19:19282523 G/A cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.38 -6.33 -0.32 7.79e-10 IgG glycosylation; LIHC cis rs6429082 0.683 rs2131920 chr1:235579912 T/A cg26050004 chr1:235667680 B3GALNT2 -0.49 -7.42 -0.37 9.23e-13 Adiposity; LIHC cis rs9733 0.593 rs10888384 chr1:150574256 C/T cg17724175 chr1:150552817 MCL1 -0.38 -7.67 -0.38 1.82e-13 Tonsillectomy; LIHC cis rs743757 0.938 rs2282753 chr3:50436716 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.51 7.97 0.4 2.47e-14 Diastolic blood pressure; LIHC cis rs2836950 0.565 rs7278297 chr21:40625752 A/C cg06238570 chr21:40685208 BRWD1 -0.46 -7.41 -0.37 9.73e-13 Menarche (age at onset); LIHC cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg06108461 chr20:60628389 TAF4 -1.02 -17.58 -0.69 9.47e-50 Body mass index; LIHC cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg11890956 chr21:40555474 PSMG1 1.08 15.65 0.65 4.97e-42 Cognitive function; LIHC cis rs360798 0.532 rs11125942 chr2:62966758 T/C cg17519650 chr2:63277830 OTX1 -0.42 -6.63 -0.34 1.3100000000000001e-10 Coronary artery disease; LIHC cis rs7618501 0.602 rs2624853 chr3:50128893 A/G cg24110177 chr3:50126178 RBM5 0.53 8.55 0.42 4.03e-16 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.874 rs10843366 chr12:29407903 T/C cg12903224 chr12:29470962 FAR2 -0.42 -6.73 -0.34 7.04e-11 QT interval; LIHC cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.18 -0.55 1.37e-28 Alzheimer's disease; LIHC cis rs6988636 1.000 rs4282551 chr8:124185916 G/A cg15893493 chr8:124194847 FAM83A 0.89 8.3 0.41 2.48e-15 Urinary uromodulin levels; LIHC cis rs11690935 0.959 rs10204622 chr2:172588982 C/T cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.77 -0.69 1.66e-50 Schizophrenia; LIHC cis rs8141529 0.588 rs10222249 chr22:29257147 A/G cg02153584 chr22:29168773 CCDC117 0.39 5.74 0.3 2.12e-8 Lymphocyte counts; LIHC cis rs5753618 0.509 rs4820951 chr22:31586248 G/A cg22777020 chr22:31556080 RNF185 -0.56 -6.33 -0.32 7.64e-10 Colorectal cancer; LIHC cis rs10484885 0.824 rs72919981 chr6:90528977 T/C cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.69 -0.34 9.39e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs4631830 0.720 rs898343 chr10:51505403 A/G cg20129853 chr10:51489980 NA 0.4 8.66 0.42 1.88e-16 Prostate-specific antigen levels; LIHC cis rs7772486 0.727 rs12190966 chr6:146146820 T/G cg23711669 chr6:146136114 FBXO30 0.63 11.35 0.52 1.44e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 1.000 rs430477 chr6:167389851 T/C cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs249954 0.512 rs35634 chr16:23697679 C/T cg05131483 chr16:23706242 ERN2 0.37 6.05 0.31 3.82e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg07414643 chr4:187882934 NA 0.23 5.97 0.31 6.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4423214 0.879 rs1792283 chr11:71135136 T/C cg05163923 chr11:71159392 DHCR7 -0.66 -9.16 -0.44 5.01e-18 Vitamin D levels; LIHC cis rs7487075 0.619 rs2408498 chr12:46796900 G/A cg23829395 chr12:46796953 NA 0.36 6.34 0.32 7.12e-10 Itch intensity from mosquito bite; LIHC cis rs6964587 1.000 rs10234071 chr7:91645152 C/G cg17063962 chr7:91808500 NA -1.0 -19.24 -0.72 2.07e-56 Breast cancer; LIHC cis rs9457247 0.534 rs2757053 chr6:167380338 A/C cg23791538 chr6:167370224 RNASET2 0.76 14.6 0.62 7.58e-38 Crohn's disease; LIHC cis rs1538970 0.924 rs4660858 chr1:45936351 G/A cg05343316 chr1:45956843 TESK2 0.58 8.61 0.42 2.68e-16 Platelet count; LIHC cis rs3008870 0.755 rs2815363 chr1:67497221 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.67 -11.44 -0.53 7.1e-26 Lymphocyte percentage of white cells; LIHC cis rs12291225 0.546 rs11023199 chr11:14394258 A/G cg05501817 chr11:14380813 RRAS2 -0.45 -6.36 -0.33 6.39e-10 Sense of smell; LIHC cis rs903552 1.000 rs12904206 chr15:102006294 C/T cg06707286 chr15:102010195 PCSK6 -0.44 -6.26 -0.32 1.13e-9 Diabetic kidney disease; LIHC cis rs7408868 1.000 rs10415431 chr19:15277027 G/A cg14696996 chr19:15285081 NOTCH3 0.53 7.11 0.36 6.93e-12 Pulse pressure; LIHC cis rs10752881 0.935 rs12082051 chr1:183051614 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Colorectal cancer; LIHC trans rs3783890 1.000 rs3783890 chr14:93790276 T/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.32 0.32 8.12e-10 Body mass index; LIHC trans rs1814175 0.587 rs7948538 chr11:50021353 A/C cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC trans rs2727020 0.595 rs10839286 chr11:49497063 C/A cg18944383 chr4:111397179 ENPEP 0.25 6.31 0.32 8.46e-10 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10996143 chr20:1373995 FKBP1A 0.44 6.89 0.35 2.75e-11 Pancreatic cancer; LIHC cis rs3106136 0.967 rs17310526 chr4:95222227 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.9 -0.39 3.77e-14 Capecitabine sensitivity; LIHC cis rs7592578 0.771 rs12053190 chr2:191383348 A/G cg27211696 chr2:191398769 TMEM194B -0.6 -8.03 -0.4 1.63e-14 Diastolic blood pressure; LIHC cis rs858239 0.600 rs59073109 chr7:23133226 C/A cg23682824 chr7:23144976 KLHL7 0.4 6.08 0.31 3.27e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg00091569 chr3:40428383 ENTPD3 0.4 6.67 0.34 1.03e-10 Renal cell carcinoma; LIHC cis rs763121 0.853 rs5750627 chr22:38982321 A/G cg06022373 chr22:39101656 GTPBP1 0.75 15.3 0.64 1.21e-40 Menopause (age at onset); LIHC cis rs7647973 0.593 rs59684465 chr3:49874246 C/T cg03060546 chr3:49711283 APEH -0.6 -6.97 -0.35 1.69e-11 Menarche (age at onset); LIHC cis rs959260 1.000 rs4789185 chr17:73383368 C/T cg20590849 chr17:73267439 MIF4GD -0.54 -5.8 -0.3 1.51e-8 Systemic lupus erythematosus; LIHC cis rs8038465 0.638 rs8036954 chr15:73974282 T/C cg15420318 chr15:73925796 NPTN 0.4 6.25 0.32 1.24e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9807841 0.500 rs1368459 chr19:10835338 C/G cg17710535 chr19:10819994 QTRT1 0.4 6.11 0.31 2.68e-9 Inflammatory skin disease; LIHC cis rs34779708 0.966 rs17591781 chr10:35498538 G/A cg03585969 chr10:35415529 CREM 0.85 12.81 0.57 6.11e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg11764359 chr7:65958608 NA 0.68 9.14 0.44 5.58e-18 Aortic root size; LIHC cis rs8067545 0.611 rs2703775 chr17:20134466 A/G cg13482628 chr17:19912719 NA -0.44 -7.21 -0.36 3.55e-12 Schizophrenia; LIHC cis rs7940866 0.903 rs2324316 chr11:130872353 G/T cg12179176 chr11:130786555 SNX19 0.56 7.87 0.39 4.6e-14 Schizophrenia; LIHC cis rs7789940 0.904 rs12531348 chr7:75937191 G/C cg10167463 chr7:75959203 YWHAG -0.42 -6.39 -0.33 5.38e-10 Multiple sclerosis; LIHC cis rs10876993 0.890 rs4760165 chr12:58063801 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.3 -0.32 8.98e-10 Celiac disease or Rheumatoid arthritis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08413565 chr3:129035733 H1FX;C3orf47 0.44 6.53 0.33 2.42e-10 Cognitive function; LIHC trans rs2727020 0.658 rs7111215 chr11:49430552 T/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.54 -0.73 1.25e-57 Coronary artery disease; LIHC cis rs910316 0.763 rs175016 chr14:75459633 C/T cg08847533 chr14:75593920 NEK9 -0.87 -17.89 -0.7 5.68e-51 Height; LIHC cis rs7833986 0.501 rs72653978 chr8:57018393 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.82 8.36 0.41 1.62e-15 Height; LIHC cis rs35306767 0.903 rs11253495 chr10:937064 C/T cg20503657 chr10:835505 NA 0.98 11.38 0.52 1.18e-25 Eosinophil percentage of granulocytes; LIHC cis rs9291683 0.609 rs13149985 chr4:10028390 G/A cg11266682 chr4:10021025 SLC2A9 0.34 7.34 0.37 1.59e-12 Bone mineral density; LIHC cis rs5769765 0.908 rs2319464 chr22:50265777 A/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.38 0.45 9.63e-19 Platelet count; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06289967 chr15:41523422 CHP;EXD1 -0.55 -6.39 -0.33 5.54e-10 Systolic blood pressure; LIHC cis rs1003719 0.788 rs7276917 chr21:38451334 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.31 0.55 4.54e-29 Eye color traits; LIHC cis rs7927592 0.871 rs12941 chr11:68382193 C/T cg20283391 chr11:68216788 NA -0.52 -7.7 -0.38 1.43e-13 Total body bone mineral density; LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg21747090 chr2:27597821 SNX17 -0.46 -7.0 -0.35 1.37e-11 Total body bone mineral density; LIHC trans rs17023017 1.000 rs17023017 chr4:96025094 A/C cg02979839 chr5:176957063 FAM193B 0.37 6.05 0.31 3.86e-9 Hen's egg allergy; LIHC cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs6831352 1.000 rs10017466 chr4:100055800 C/T cg12011299 chr4:100065546 ADH4 0.59 10.94 0.51 4.32e-24 Alcohol dependence; LIHC cis rs701145 0.556 rs355764 chr3:154013480 A/T cg16511985 chr3:153974050 SGEF 0.42 8.99 0.44 1.71e-17 Coronary artery disease; LIHC trans rs1814175 0.645 rs1851853 chr11:49953434 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC trans rs6759952 0.649 rs1382435 chr2:218296003 A/G cg22946670 chr1:154909930 PMVK 0.42 6.04 0.31 4.13e-9 Thyroid cancer; LIHC cis rs3849570 0.925 rs9841087 chr3:81907949 A/G cg07356753 chr3:81810745 GBE1 -0.54 -8.55 -0.42 4.05e-16 Waist circumference;Body mass index; LIHC cis rs10883723 0.810 rs17782574 chr10:104279394 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.64 0.56 2.67e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1075232 0.826 rs16956738 chr15:31736231 C/T cg01030201 chr15:31746330 NA 0.69 5.83 0.3 1.29e-8 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg06634786 chr22:41940651 POLR3H 0.83 8.89 0.43 3.5e-17 Vitiligo; LIHC cis rs7937890 0.706 rs7115393 chr11:14268378 T/A cg22961513 chr11:14280813 SPON1 0.42 5.75 0.3 1.99e-8 Mitochondrial DNA levels; LIHC cis rs12986413 0.559 rs1859951 chr19:2142633 C/G cg09261902 chr19:2140048 AP3D1 0.39 6.67 0.34 1.01e-10 Height; LIHC cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.59 -0.56 4.11e-30 Alzheimer's disease; LIHC cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs9322817 0.691 rs1455935 chr6:105230312 C/G cg02098413 chr6:105308735 HACE1 -0.43 -7.84 -0.39 5.92e-14 Thyroid stimulating hormone; LIHC cis rs6933660 0.512 rs13198669 chr6:151799924 A/G cg03627880 chr6:151815985 C6orf97 0.42 6.14 0.32 2.26e-9 Menarche (age at onset); LIHC cis rs6964587 0.967 rs6974827 chr7:91772945 C/T cg17063962 chr7:91808500 NA 1.06 22.62 0.77 6.65e-70 Breast cancer; LIHC trans rs62103177 0.608 rs551643 chr18:77838970 C/G cg05926928 chr17:57297772 GDPD1 -0.61 -6.82 -0.35 4.06e-11 Opioid sensitivity; LIHC cis rs11711311 0.747 rs11928590 chr3:113343478 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -6.62 -0.34 1.43e-10 IgG glycosylation; LIHC cis rs4919087 1.000 rs11189122 chr10:99072595 G/A cg25902810 chr10:99078978 FRAT1 0.7 10.9 0.51 6.1e-24 Monocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09098825 chr3:47866946 DHX30 0.44 6.12 0.31 2.54e-9 Lung function (FEV1/FVC); LIHC cis rs240764 0.658 rs9399685 chr6:101204318 C/G cg09795085 chr6:101329169 ASCC3 -0.42 -5.79 -0.3 1.58e-8 Neuroticism; LIHC cis rs6750047 0.638 rs336031 chr2:38265130 C/A cg07380506 chr2:38303506 CYP1B1 -0.51 -5.98 -0.31 5.69e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs11792861 0.781 rs11789252 chr9:111762010 A/T cg05043794 chr9:111880884 C9orf5 -0.31 -7.14 -0.36 5.6e-12 Menarche (age at onset); LIHC cis rs921968 0.565 rs12694439 chr2:219590871 A/G cg02985541 chr2:219472218 PLCD4 -0.38 -6.66 -0.34 1.07e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6461049 0.800 rs2398706 chr7:2156338 A/T cg20295408 chr7:1910781 MAD1L1 -0.42 -6.25 -0.32 1.21e-9 Schizophrenia; LIHC cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg09904177 chr6:26538194 HMGN4 0.54 10.54 0.5 1.09e-22 Intelligence (multi-trait analysis); LIHC cis rs3018712 0.532 rs11228312 chr11:68415517 G/T cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.12e-8 Total body bone mineral density; LIHC cis rs7617773 0.676 rs13060020 chr3:48372646 C/T cg11946769 chr3:48343235 NME6 0.92 11.74 0.54 5.67e-27 Coronary artery disease; LIHC cis rs796364 0.806 rs1509832 chr2:200874443 G/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 7.5 0.38 5.46e-13 Schizophrenia; LIHC cis rs2292096 1.000 rs16847180 chr1:200731556 A/T cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -5.97 -0.31 5.97e-9 Epilepsy; LIHC cis rs3770081 1.000 rs2241437 chr2:86360573 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.85 -9.09 -0.44 8.29e-18 Facial emotion recognition (sad faces); LIHC cis rs2842992 0.692 rs1128661 chr6:160211554 T/G cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.14 0.44 5.61e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg17971929 chr21:40555470 PSMG1 -0.52 -8.03 -0.4 1.56e-14 Cognitive function; LIHC cis rs6762 0.748 rs3059 chr11:840319 C/T cg15787769 chr11:842744 TSPAN4;POLR2L -0.65 -7.82 -0.39 6.42e-14 Mean platelet volume; LIHC cis rs7264396 0.676 rs6058383 chr20:34556005 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs34779708 0.966 rs2045917 chr10:35418526 G/A cg04310649 chr10:35416472 CREM -0.44 -5.9 -0.3 8.73e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1664789 1.000 rs1664783 chr5:53279515 T/A ch.5.1024479R chr5:53302184 ARL15 0.51 8.33 0.41 2.03e-15 Waist circumference adjusted for body mass index; LIHC cis rs1707322 1.000 rs11211223 chr1:46380605 C/T cg06784218 chr1:46089804 CCDC17 0.36 6.23 0.32 1.4e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1801251 1.000 rs13008942 chr2:233594875 G/A cg08000102 chr2:233561755 GIGYF2 0.76 11.52 0.53 3.64e-26 Coronary artery disease; LIHC cis rs7572733 0.534 rs1518365 chr2:198809410 T/C cg00792783 chr2:198669748 PLCL1 0.46 6.81 0.35 4.49e-11 Dermatomyositis; LIHC cis rs12926788 0.546 rs200537 chr16:24747787 G/C cg00339695 chr16:24857497 SLC5A11 -0.7 -10.56 -0.5 9.63e-23 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs12744310 0.887 rs35436312 chr1:41793358 G/A cg03962019 chr1:41807865 NA 0.39 6.38 0.33 5.89e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs1864585 0.520 rs73208790 chr8:10680025 T/A cg26278703 chr11:58910052 FAM111A 0.74 6.83 0.35 3.95e-11 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs743757 1.000 rs2236988 chr3:50504896 G/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.4 5.71 0.3 2.45e-8 Diastolic blood pressure; LIHC cis rs9818758 0.607 rs34784192 chr3:49274823 G/T cg06212747 chr3:49208901 KLHDC8B -0.65 -5.77 -0.3 1.75e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9359856 0.600 rs17584763 chr6:90502088 G/A cg13799429 chr6:90582589 CASP8AP2 -0.66 -5.84 -0.3 1.22e-8 Bipolar disorder; LIHC cis rs4660306 1.000 rs7536557 chr1:45992114 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.54 -6.58 -0.34 1.74e-10 Homocysteine levels; LIHC cis rs3106136 0.967 rs61514245 chr4:95165053 C/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.05 -0.4 1.37e-14 Capecitabine sensitivity; LIHC cis rs57590327 0.503 rs1461611 chr3:81512061 C/A cg07356753 chr3:81810745 GBE1 0.46 6.84 0.35 3.7e-11 Extraversion; LIHC cis rs9388451 0.505 rs9372828 chr6:126175185 A/T cg05901451 chr6:126070800 HEY2 -0.48 -8.26 -0.41 3.13e-15 Brugada syndrome; LIHC cis rs1008375 0.966 rs1860591 chr4:17577329 A/G cg16339924 chr4:17578868 LAP3 0.45 6.24 0.32 1.33e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs12478296 1.000 rs55758933 chr2:243040289 T/C cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.95e-15 Obesity-related traits; LIHC cis rs1144333 0.737 rs1144339 chr1:76280543 A/G cg03433033 chr1:76189801 ACADM -0.56 -8.58 -0.42 3.33e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs60871478 1.000 rs34260834 chr7:822958 A/G cg27478167 chr7:817139 HEATR2 -0.41 -5.92 -0.3 7.9e-9 Cerebrospinal P-tau181p levels; LIHC cis rs7927592 0.956 rs12277225 chr11:68340967 T/C cg20283391 chr11:68216788 NA -0.51 -7.63 -0.38 2.36e-13 Total body bone mineral density; LIHC cis rs2976388 0.609 rs2717603 chr8:143803193 T/C cg06565975 chr8:143823917 SLURP1 0.34 6.68 0.34 9.62e-11 Urinary tract infection frequency; LIHC cis rs965469 0.947 rs6037578 chr20:3345911 T/C cg25506879 chr20:3388711 C20orf194 -0.54 -6.52 -0.33 2.58e-10 IFN-related cytopenia; LIHC trans rs2797160 1.000 rs1418951 chr6:125996185 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.44 -6.42 -0.33 4.68e-10 Endometrial cancer; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 1.98e-12 Developmental language disorder (linguistic errors); LIHC cis rs80282103 0.764 rs10047383 chr10:1103095 A/G cg08668510 chr10:1095578 IDI1 0.67 6.78 0.34 5.16e-11 Glomerular filtration rate (creatinine); LIHC cis rs35110281 0.782 rs6518302 chr21:45018478 A/G cg01579765 chr21:45077557 HSF2BP -0.35 -6.65 -0.34 1.13e-10 Mean corpuscular volume; LIHC cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg16262614 chr3:133464971 TF 0.29 6.47 0.33 3.44e-10 Iron status biomarkers; LIHC cis rs10193935 0.901 rs6544536 chr2:42522042 G/A cg27598129 chr2:42591480 NA -0.7 -11.14 -0.52 8.29e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs3741404 0.825 rs2845597 chr11:63954370 G/A cg18225595 chr11:63971243 STIP1 0.67 10.83 0.51 1.03e-23 Platelet count; LIHC cis rs7726839 0.540 rs4957080 chr5:644552 A/C cg09021430 chr5:549028 NA 0.42 8.38 0.41 1.4e-15 Obesity-related traits; LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC cis rs7100689 0.577 rs1340385 chr10:82058851 G/A cg01528321 chr10:82214614 TSPAN14 0.87 11.9 0.54 1.43e-27 Post bronchodilator FEV1; LIHC cis rs16828019 0.852 rs11209576 chr1:41586029 T/C cg20697417 chr1:41786797 NA 0.32 6.12 0.31 2.52e-9 Intelligence (multi-trait analysis); LIHC cis rs2857078 0.627 rs1476512 chr17:42330122 C/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.44 -6.09 -0.31 3.12e-9 Red cell distribution width;Reticulocyte count; LIHC cis rs2070488 0.965 rs1984312 chr3:38538466 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.94 -16.15 -0.66 5.05e-44 Electrocardiographic conduction measures; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23181591 chr8:123793873 ZHX2 0.42 6.05 0.31 3.75e-9 Pancreatic cancer; LIHC trans rs7395662 0.611 rs7478698 chr11:48549139 T/C cg15704280 chr7:45808275 SEPT13 -0.46 -6.9 -0.35 2.56e-11 HDL cholesterol; LIHC cis rs4319547 0.506 rs2062488 chr12:122804256 C/T cg05707623 chr12:122985044 ZCCHC8 0.48 6.36 0.33 6.59e-10 Body mass index; LIHC cis rs5770917 1.000 rs3180872 chr22:51017394 G/C cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.45 -6.56 -0.33 1.99e-10 Narcolepsy; LIHC trans rs916888 0.773 rs199439 chr17:44793503 A/G cg12297030 chr17:43662878 NA -0.63 -6.08 -0.31 3.25e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4975616 0.869 rs370348 chr5:1331219 A/G cg06550200 chr5:1325588 CLPTM1L -0.69 -11.0 -0.51 2.64e-24 Lung cancer; LIHC cis rs250677 0.652 rs168751 chr5:148438264 C/T cg18129178 chr5:148520854 ABLIM3 -0.55 -7.05 -0.36 1.03e-11 Breast cancer; LIHC cis rs17102423 0.723 rs8181938 chr14:65555712 A/G cg11161011 chr14:65562177 MAX -0.53 -7.6 -0.38 2.92e-13 Obesity-related traits; LIHC cis rs9296092 0.560 rs3846853 chr6:33528194 C/G cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs6714710 0.812 rs6543040 chr2:98343254 C/T cg26665480 chr2:98280029 ACTR1B 0.41 5.91 0.3 8.12e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs7903847 0.620 rs11189168 chr10:99125769 T/C cg06359132 chr10:99160096 RRP12 -0.4 -6.33 -0.32 7.89e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs568617 0.953 rs583887 chr11:65644027 T/C cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.44 -0.33 4.17e-10 Crohn's disease; LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg06656553 chr16:89960601 TCF25 -0.46 -5.91 -0.3 8.17e-9 Skin colour saturation; LIHC cis rs2153535 0.601 rs9505473 chr6:8538777 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.51 0.42 5.35e-16 Motion sickness; LIHC cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7197653 0.748 rs8060690 chr16:68340085 G/T cg05110241 chr16:68378359 PRMT7 -0.96 -10.22 -0.48 1.46e-21 Magnesium levels; LIHC trans rs11098499 0.754 rs12507565 chr4:120251121 G/A cg25214090 chr10:38739885 LOC399744 0.51 8.29 0.41 2.61e-15 Corneal astigmatism; LIHC cis rs28374715 0.532 rs28535540 chr15:41659277 G/A cg18705301 chr15:41695430 NDUFAF1 -1.22 -18.35 -0.7 7.66e-53 Ulcerative colitis; LIHC cis rs7647973 0.769 rs4974081 chr3:49070499 A/G cg20833759 chr3:49053208 WDR6;DALRD3 -0.52 -6.14 -0.32 2.26e-9 Menarche (age at onset); LIHC cis rs11971779 0.618 rs13068 chr7:139104141 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.13 0.48 2.92e-21 Diisocyanate-induced asthma; LIHC cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg06873352 chr17:61820015 STRADA -0.54 -8.77 -0.43 8.66e-17 Prudent dietary pattern; LIHC cis rs1707322 1.000 rs10890381 chr1:46451771 T/G cg06784218 chr1:46089804 CCDC17 0.39 6.91 0.35 2.44e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1023500 0.573 rs4822088 chr22:42470589 G/C cg04733989 chr22:42467013 NAGA 0.68 9.86 0.47 2.3e-20 Schizophrenia; LIHC cis rs12586317 0.553 rs3809448 chr14:35515096 C/T cg05294307 chr14:35346193 BAZ1A -0.5 -7.26 -0.37 2.64e-12 Psoriasis; LIHC cis rs12477438 0.765 rs6722164 chr2:99561527 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.1 -0.4 9.71e-15 Chronic sinus infection; LIHC cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg00166722 chr3:10149974 C3orf24 0.51 6.03 0.31 4.36e-9 Alzheimer's disease; LIHC cis rs2839186 0.587 rs35679325 chr21:47640980 A/G cg13126279 chr21:47581558 C21orf56 0.37 5.73 0.3 2.2e-8 Testicular germ cell tumor; LIHC cis rs12922040 0.651 rs35288467 chr16:15866954 C/A cg08214245 chr16:15829296 MYH11 -0.29 -5.93 -0.31 7.28e-9 Serum uric acid levels in response to allopurinol in gout; LIHC trans rs17685 0.753 rs6976532 chr7:75681094 A/G cg19862616 chr7:65841803 NCRNA00174 0.89 18.6 0.71 7.32e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1873147 0.569 rs58819603 chr15:63310866 T/A cg05771511 chr15:63340396 TPM1 -0.44 -5.94 -0.31 7.01e-9 Orofacial clefts; LIHC cis rs910316 0.712 rs175037 chr14:75465038 T/C cg11812906 chr14:75593930 NEK9 -0.74 -13.92 -0.6 3.33e-35 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19553056 chr4:142142166 ZNF330 0.41 6.51 0.33 2.61e-10 Cognitive function; LIHC cis rs7552404 1.000 rs28602663 chr1:76235355 C/T cg22875332 chr1:76189707 ACADM 0.45 6.39 0.33 5.32e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10927875 0.619 rs2102664 chr1:16130169 A/G cg21385522 chr1:16154831 NA -0.73 -10.26 -0.49 1.02e-21 Dilated cardiomyopathy; LIHC cis rs7659604 0.605 rs1507994 chr4:122749541 C/T cg20573242 chr4:122745356 CCNA2 0.52 8.12 0.4 8.61e-15 Type 2 diabetes; LIHC cis rs2404602 0.647 rs11072612 chr15:76960984 A/T cg23625390 chr15:77176239 SCAPER -0.55 -9.04 -0.44 1.18e-17 Blood metabolite levels; LIHC cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg13393036 chr8:95962371 TP53INP1 -0.4 -8.92 -0.43 2.9e-17 Type 2 diabetes; LIHC cis rs9911578 1.000 rs9901114 chr17:56575208 G/A cg12560992 chr17:57184187 TRIM37 -0.95 -16.99 -0.68 2.33e-47 Intelligence (multi-trait analysis); LIHC cis rs2250402 0.510 rs8031319 chr15:40323692 A/G cg10636054 chr15:40330586 SRP14 0.69 8.29 0.41 2.64e-15 Corneal curvature; LIHC cis rs6430585 0.583 rs3754689 chr2:136590746 C/T cg25344623 chr2:136566232 LCT -0.33 -5.85 -0.3 1.18e-8 Corneal structure; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs3806843 1.000 rs6870764 chr5:140171790 C/T cg19875535 chr5:140030758 IK 0.36 5.9 0.3 8.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1801251 1.000 rs4973054 chr2:233710713 G/C cg25237894 chr2:233734115 C2orf82 -0.59 -11.45 -0.53 6.32e-26 Coronary artery disease; LIHC cis rs921968 0.565 rs3770220 chr2:219619550 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7412746 0.658 rs1027699 chr1:150811712 T/C cg17724175 chr1:150552817 MCL1 0.47 9.34 0.45 1.27e-18 Melanoma; LIHC cis rs4908768 0.906 rs11121207 chr1:8681848 C/A cg25722041 chr1:8623473 RERE 0.43 5.75 0.3 2.01e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg09367891 chr1:107599246 PRMT6 0.66 10.77 0.5 1.77e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1461503 0.932 rs10892944 chr11:122843895 T/C cg14473756 chr11:122847823 NA -0.36 -6.6 -0.34 1.54e-10 Menarche (age at onset); LIHC cis rs35110281 0.667 rs4819291 chr21:45123139 G/A cg21573476 chr21:45109991 RRP1B -0.52 -9.88 -0.47 2.06e-20 Mean corpuscular volume; LIHC cis rs2072499 1.000 rs2072499 chr1:156169610 A/G cg24450063 chr1:156163899 SLC25A44 1.07 18.59 0.71 8.47e-54 Testicular germ cell tumor; LIHC cis rs11792861 0.926 rs72607166 chr9:111821530 A/C cg13535736 chr9:111863775 C9orf5 -0.4 -5.99 -0.31 5.37e-9 Menarche (age at onset); LIHC cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.76 0.3 1.83e-8 Menopause (age at onset); LIHC cis rs28830936 0.966 rs28680296 chr15:42121538 C/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.14 -0.31 2.34e-9 Diastolic blood pressure; LIHC cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg05697976 chr12:29376483 FAR2 0.32 6.37 0.33 5.95e-10 QT interval; LIHC cis rs17826219 0.706 rs28469200 chr17:29133572 T/A cg13385521 chr17:29058706 SUZ12P 0.81 8.01 0.4 1.77e-14 Body mass index; LIHC cis rs3796619 1.000 rs1466214 chr4:1073760 C/T cg27284194 chr4:1044797 NA 0.61 10.09 0.48 4.11e-21 Recombination rate (males); LIHC cis rs7091068 0.671 rs588912 chr10:95402929 T/C cg20715218 chr10:95462985 C10orf4 -0.61 -6.95 -0.35 1.83e-11 Urinary tract infection frequency; LIHC cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg19774624 chr17:42201019 HDAC5 -0.8 -12.48 -0.56 1.06e-29 Total body bone mineral density; LIHC cis rs11958404 0.932 rs72816574 chr5:157429882 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.11e-27 IgG glycosylation; LIHC cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg10560079 chr2:191398806 TMEM194B -0.5 -7.64 -0.38 2.15e-13 Pulse pressure; LIHC cis rs769267 0.965 rs4808937 chr19:19398005 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.6 9.48 0.46 4.3e-19 Tonsillectomy; LIHC trans rs116095464 0.558 rs10475136 chr5:232796 A/G cg00938859 chr5:1591904 SDHAP3 0.59 7.19 0.36 4.19e-12 Breast cancer; LIHC cis rs7945718 0.967 rs10765990 chr11:12769444 G/A cg25843174 chr11:12811716 TEAD1 0.28 6.51 0.33 2.67e-10 Educational attainment (years of education); LIHC cis rs7116495 0.881 rs598835 chr11:71797727 C/T cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs6502050 0.835 rs7221544 chr17:80087337 C/T cg11859384 chr17:80120422 CCDC57 0.43 5.87 0.3 1.04e-8 Life satisfaction; LIHC trans rs35110281 0.565 rs7278003 chr21:44966069 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.47 6.43 0.33 4.4e-10 Mean corpuscular volume; LIHC cis rs1538970 0.924 rs2088100 chr1:45877575 C/T cg24296786 chr1:45957014 TESK2 -0.5 -7.3 -0.37 2.09e-12 Platelet count; LIHC cis rs1401999 1.000 rs869417 chr3:183689138 T/C cg05044414 chr3:183734942 ABCC5 0.35 6.11 0.31 2.76e-9 Anterior chamber depth; LIHC cis rs4927850 0.958 rs2044599 chr3:195736740 G/A cg01181863 chr3:195395398 SDHAP2 -0.63 -8.0 -0.4 1.98e-14 Pancreatic cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07327396 chr4:128886243 C4orf29;MFSD8 0.44 6.66 0.34 1.08e-10 Cognitive function; LIHC cis rs12893668 0.603 rs61637848 chr14:104096031 C/T cg08213375 chr14:104286397 PPP1R13B 0.36 5.86 0.3 1.11e-8 Reticulocyte count; LIHC cis rs3736485 0.966 rs6493513 chr15:51910174 G/A cg08986416 chr15:51914746 DMXL2 -0.47 -6.97 -0.35 1.65e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4474465 0.688 rs7937225 chr11:78278126 T/A cg27205649 chr11:78285834 NARS2 0.5 7.89 0.39 4.19e-14 Alzheimer's disease (survival time); LIHC cis rs2840044 1.000 rs9913003 chr17:33893904 C/A cg20932281 chr17:33905541 PEX12 0.42 5.74 0.3 2.12e-8 Response to radiotherapy in cancer (late toxicity); LIHC trans rs2262909 0.853 rs56207853 chr19:22292357 C/T cg05197062 chr11:11642011 GALNTL4 0.44 6.45 0.33 3.88e-10 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs7927771 0.965 rs3817335 chr11:47643891 T/A cg20307385 chr11:47447363 PSMC3 -0.46 -5.98 -0.31 5.68e-9 Subjective well-being; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16123319 chr15:49913299 DTWD1;C15orf33 -0.58 -6.6 -0.34 1.6e-10 Systolic blood pressure; LIHC cis rs929354 0.772 rs2023977 chr7:156996022 C/G cg16102536 chr7:156981717 UBE3C 0.35 5.92 0.3 7.91e-9 Body mass index; LIHC cis rs1801251 1.000 rs1446311 chr2:233705071 G/A cg25237894 chr2:233734115 C2orf82 -0.58 -11.39 -0.52 1.1e-25 Coronary artery disease; LIHC cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg03806693 chr22:41940476 POLR3H -1.14 -13.43 -0.59 2.6e-33 Vitiligo; LIHC cis rs7116495 1.000 rs10736786 chr11:71763274 C/T cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs4908768 0.906 rs114812780 chr1:8528854 G/T cg20416874 chr1:8611966 RERE 0.58 9.08 0.44 9.16e-18 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs7395662 0.570 rs11039737 chr11:48450200 G/A cg15704280 chr7:45808275 SEPT13 -0.42 -6.44 -0.33 4.08e-10 HDL cholesterol; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02951695 chr10:134400351 INPP5A 0.41 6.05 0.31 3.86e-9 Immature fraction of reticulocytes; LIHC cis rs11098499 0.908 rs11098527 chr4:120399906 A/G cg09307838 chr4:120376055 NA 0.77 12.14 0.55 1.95e-28 Corneal astigmatism; LIHC cis rs4319547 0.760 rs61954973 chr12:123074168 T/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.13 -0.36 5.98e-12 Body mass index; LIHC cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg03735888 chr19:58951602 ZNF132 0.4 7.03 0.36 1.13e-11 Uric acid clearance; LIHC trans rs208520 0.690 rs207107 chr6:66794385 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs9393692 0.875 rs2142703 chr6:26289605 A/G cg13736514 chr6:26305472 NA -0.36 -6.07 -0.31 3.34e-9 Educational attainment; LIHC cis rs12701220 0.894 rs10257744 chr7:1045612 C/T cg26769984 chr7:1090371 C7orf50 0.6 7.56 0.38 3.76e-13 Bronchopulmonary dysplasia; LIHC cis rs9393692 0.557 rs62394768 chr6:26326033 C/T cg00631329 chr6:26305371 NA -0.34 -5.74 -0.3 2.05e-8 Educational attainment; LIHC cis rs12474201 0.928 rs7594523 chr2:46935791 G/C cg06386533 chr2:46925753 SOCS5 0.73 8.23 0.41 4.06e-15 Height; LIHC cis rs6831256 0.505 rs11947277 chr4:3473751 C/T cg23495837 chr4:3480318 DOK7 -0.39 -6.22 -0.32 1.41e-9 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs9549328 0.700 rs2185001 chr13:113616369 G/T cg18289306 chr13:113640169 MCF2L 0.42 6.18 0.32 1.78e-9 Systolic blood pressure; LIHC cis rs968567 0.501 rs174553 chr11:61575158 A/G cg07689907 chr11:61582574 FADS1 0.39 5.77 0.3 1.78e-8 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs7903847 0.642 rs11812223 chr10:99158455 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.44 -0.33 4.04e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11779988 0.545 rs4124900 chr8:17785266 A/G cg01800426 chr8:17659068 MTUS1 -0.42 -5.92 -0.3 7.96e-9 Breast cancer; LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg12648201 chr2:27665141 KRTCAP3 -0.42 -5.82 -0.3 1.34e-8 Total body bone mineral density; LIHC cis rs3768617 0.754 rs6673768 chr1:182983396 G/T ch.1.3577855R chr1:183094577 LAMC1 0.47 7.4 0.37 1.07e-12 Fuchs's corneal dystrophy; LIHC cis rs1707322 1.000 rs11211222 chr1:46367757 T/C cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.84e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12922040 0.651 rs35288467 chr16:15866954 C/A cg27174420 chr16:15820903 MYH11 -0.33 -5.76 -0.3 1.89e-8 Serum uric acid levels in response to allopurinol in gout; LIHC cis rs4660306 1.000 rs6429569 chr1:46001330 A/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.5 -6.2 -0.32 1.66e-9 Homocysteine levels; LIHC cis rs7582180 0.764 rs7425449 chr2:100928393 A/G cg14675211 chr2:100938903 LONRF2 0.54 8.36 0.41 1.61e-15 Intelligence (multi-trait analysis); LIHC cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg12756686 chr19:29218302 NA 0.44 6.79 0.34 4.88e-11 Methadone dose in opioid dependence; LIHC cis rs116979167 0.545 rs1706914 chr7:105196445 A/T cg19920283 chr7:105172520 RINT1 0.47 5.74 0.3 2.09e-8 Bipolar disorder (body mass index interaction); LIHC cis rs12971120 0.891 rs12605820 chr18:72167802 G/A cg25817165 chr18:72167213 CNDP2 -0.71 -12.25 -0.55 7.5e-29 Refractive error; LIHC cis rs4631830 0.832 rs10825652 chr10:51510761 G/A cg20129853 chr10:51489980 NA 0.42 9.0 0.44 1.54e-17 Prostate-specific antigen levels; LIHC cis rs1570989 0.571 rs6916066 chr6:12016009 G/C cg17804551 chr6:12015979 HIVEP1 0.41 7.18 0.36 4.44e-12 Alcohol and nicotine co-dependence; LIHC cis rs7959452 0.605 rs12819406 chr12:69696400 G/T cg14784868 chr12:69753453 YEATS4 0.88 17.03 0.68 1.5e-47 Blood protein levels; LIHC cis rs9611519 0.780 rs1535048 chr22:41684093 C/T cg06634786 chr22:41940651 POLR3H -0.52 -6.19 -0.32 1.68e-9 Neuroticism; LIHC cis rs3213545 0.659 rs2259693 chr12:121457995 G/A cg02403541 chr12:121454288 C12orf43 0.67 12.96 0.57 1.57e-31 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs6500602 0.702 rs11076834 chr16:4549583 C/G cg08645402 chr16:4508243 NA 0.44 8.61 0.42 2.69e-16 Schizophrenia; LIHC cis rs992157 0.735 rs13388024 chr2:219097773 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.61 0.59 5.31e-34 Colorectal cancer; LIHC trans rs60752752 0.852 rs6680386 chr1:153371085 A/G cg14901121 chr8:98817630 LAPTM4B 0.44 7.09 0.36 7.77e-12 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs2412488 0.893 rs17082923 chr4:54363481 C/T cg22241045 chr4:54363911 LNX1 0.46 7.65 0.38 2.07e-13 DNA methylation (variation); LIHC cis rs1538970 0.781 rs10890330 chr1:45920406 G/A cg05343316 chr1:45956843 TESK2 0.6 8.65 0.42 2.09e-16 Platelet count; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg07677032 chr17:61819896 STRADA 0.43 6.06 0.31 3.53e-9 Prudent dietary pattern; LIHC cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg17971929 chr21:40555470 PSMG1 -0.43 -6.45 -0.33 3.89e-10 Cognitive function; LIHC cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg11764359 chr7:65958608 NA -0.58 -5.98 -0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs11098699 0.784 rs6534393 chr4:124238947 C/T cg09941581 chr4:124220074 SPATA5 -0.32 -6.29 -0.32 9.56e-10 Mosquito bite size; LIHC cis rs8014204 0.935 rs2853779 chr14:75368508 G/A cg08847533 chr14:75593920 NEK9 -0.38 -6.46 -0.33 3.54e-10 Caffeine consumption; LIHC cis rs2243480 1.000 rs13235972 chr7:65883605 C/T cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC cis rs17152411 0.711 rs7096822 chr10:126664166 T/C cg07906193 chr10:126599966 NA 0.34 6.06 0.31 3.52e-9 Height; LIHC trans rs2749592 0.513 rs1208708 chr10:38085576 A/G cg17830980 chr10:43048298 ZNF37B -0.45 -8.71 -0.43 1.34e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs1814175 0.527 rs7128827 chr11:49665644 C/T cg03929089 chr4:120376271 NA 0.68 9.84 0.47 2.83e-20 Height; LIHC cis rs13191362 1.000 rs34066731 chr6:163011047 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs13108904 0.557 rs1250095 chr4:1239312 C/T cg02475777 chr4:1388615 CRIPAK -0.49 -7.36 -0.37 1.35e-12 Obesity-related traits; LIHC cis rs12478296 1.000 rs66466023 chr2:243046151 T/G cg18898632 chr2:242989856 NA -0.57 -7.72 -0.39 1.32e-13 Obesity-related traits; LIHC cis rs11628318 0.802 rs2277471 chr14:103024387 A/C cg01864069 chr14:103024347 NA 0.52 8.51 0.42 5.64e-16 Platelet count; LIHC cis rs1144333 0.655 rs931506 chr1:76401349 T/C cg10523679 chr1:76189770 ACADM 0.47 6.41 0.33 4.78e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg08392591 chr16:89556376 ANKRD11 -0.48 -7.54 -0.38 4.25e-13 Multiple myeloma (IgH translocation); LIHC cis rs7246657 0.943 rs13343502 chr19:37962292 C/T cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs10876993 0.855 rs1689604 chr12:58048304 T/C cg15848620 chr12:58087721 OS9 -0.55 -7.43 -0.37 8.96e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs708547 0.647 rs1626594 chr4:57878254 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.46 6.75 0.34 6.36e-11 Response to bleomycin (chromatid breaks); LIHC cis rs2760061 0.583 rs708110 chr1:228190805 T/A cg01200585 chr1:228362443 C1orf69 0.5 6.29 0.32 9.77e-10 Diastolic blood pressure; LIHC cis rs7762018 0.607 rs80106119 chr6:170048309 T/C cg19338460 chr6:170058176 WDR27 -0.9 -9.03 -0.44 1.28e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs3736485 0.899 rs7183479 chr15:51942207 C/G cg08986416 chr15:51914746 DMXL2 -0.43 -6.18 -0.32 1.81e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2836974 0.644 rs2836986 chr21:40702136 A/C cg17971929 chr21:40555470 PSMG1 -0.42 -6.37 -0.33 6.25e-10 Cognitive function; LIHC cis rs738321 0.756 rs11570745 chr22:38513493 C/T cg25457927 chr22:38595422 NA -0.29 -6.46 -0.33 3.53e-10 Breast cancer; LIHC cis rs4713118 0.513 rs149958 chr6:28013617 A/C cg16479474 chr6:28041457 NA 0.39 6.38 0.33 5.78e-10 Parkinson's disease; LIHC cis rs9811920 0.609 rs793447 chr3:99598278 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg12386194 chr3:101231763 SENP7 0.46 6.8 0.35 4.72e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg02290350 chr8:58132656 NA 0.47 9.29 0.45 1.8e-18 Developmental language disorder (linguistic errors); LIHC cis rs1055129 0.560 rs56248937 chr17:73915153 T/A cg14829360 chr17:73884958 NA -0.38 -6.44 -0.33 4.01e-10 White matter hyperintensity burden; LIHC cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.5 -6.7 -0.34 8.72e-11 Bipolar disorder; LIHC cis rs4820294 0.961 rs62236664 chr22:38059427 T/C cg10587741 chr22:38071170 LGALS1 0.73 12.66 0.56 2.14e-30 Fat distribution (HIV); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08058610 chr19:52674483 ZNF836 0.41 6.15 0.32 2.2e-9 Cognitive function; LIHC cis rs4930103 0.619 rs739905 chr11:1980360 G/C cg23202291 chr11:1979235 NA 0.5 7.39 0.37 1.13e-12 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs7296418 0.961 rs4148863 chr12:123569375 A/G cg06742321 chr12:123595122 PITPNM2 0.3 5.78 0.3 1.65e-8 Platelet count; LIHC cis rs8044995 0.636 rs12596500 chr16:68299771 G/A cg05110241 chr16:68378359 PRMT7 -0.63 -6.33 -0.32 7.65e-10 Schizophrenia; LIHC cis rs6840360 0.571 rs11729136 chr4:152529227 C/A cg22705602 chr4:152727874 NA -0.33 -6.4 -0.33 5.09e-10 Intelligence (multi-trait analysis); LIHC cis rs2197308 0.765 rs11182992 chr12:37935572 G/C cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs477895 1.000 rs7947143 chr11:64090422 G/A cg04317338 chr11:64019027 PLCB3 0.84 7.87 0.39 4.58e-14 Mean platelet volume; LIHC cis rs7208859 0.623 rs1054400 chr17:29109954 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7772486 0.625 rs9390355 chr6:146112942 C/T cg13319975 chr6:146136371 FBXO30 0.36 5.83 0.3 1.29e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769707 0.521 rs6009810 chr22:50059540 A/G cg01652190 chr22:50026171 C22orf34 -0.28 -5.99 -0.31 5.3e-9 Monocyte count;Monocyte percentage of white cells; LIHC cis rs412050 0.501 rs2876980 chr22:22106535 C/T cg17089214 chr22:22089827 YPEL1 -0.69 -6.36 -0.33 6.36e-10 Attention deficit hyperactivity disorder; LIHC cis rs2806561 0.704 rs2806570 chr1:23527005 C/T cg19743168 chr1:23544995 NA -0.36 -5.85 -0.3 1.15e-8 Height; LIHC cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs907683 0.559 rs11685408 chr2:220291474 T/C cg15015639 chr2:220282977 DES 0.35 8.37 0.41 1.53e-15 Resting heart rate; LIHC cis rs35110281 0.782 rs2838329 chr21:45023329 T/C cg01579765 chr21:45077557 HSF2BP -0.35 -6.65 -0.34 1.13e-10 Mean corpuscular volume; LIHC cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.95 0.31 6.79e-9 Electroencephalogram traits; LIHC cis rs74181299 0.684 rs9797989 chr2:65336529 T/C cg05010058 chr2:65284262 CEP68 -0.41 -6.78 -0.34 5.31e-11 Pulse pressure; LIHC cis rs67460515 0.596 rs35127376 chr3:160927289 T/C cg03342759 chr3:160939853 NMD3 -0.6 -8.81 -0.43 6.19e-17 Parkinson's disease; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg12419862 chr22:24373484 LOC391322 -0.73 -11.22 -0.52 4.32e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs798554 1.000 rs798544 chr7:2763102 A/G cg13628971 chr7:2884303 GNA12 -0.51 -7.42 -0.37 9.4e-13 Height; LIHC cis rs4474465 0.790 rs10751293 chr11:78250956 A/T cg27205649 chr11:78285834 NARS2 0.39 6.14 0.32 2.29e-9 Alzheimer's disease (survival time); LIHC cis rs909002 0.849 rs10914458 chr1:32096746 T/C cg13919466 chr1:32135498 COL16A1 -0.33 -6.38 -0.33 5.64e-10 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.594 rs3778965 chr7:2138296 G/A cg04267008 chr7:1944627 MAD1L1 -0.53 -8.35 -0.41 1.68e-15 Bipolar disorder and schizophrenia; LIHC cis rs10857712 0.528 rs2265638 chr10:135217175 A/G cg15472797 chr10:135243109 NA -0.4 -6.79 -0.34 4.89e-11 Systemic lupus erythematosus; LIHC cis rs240764 0.717 rs6907444 chr6:101163606 G/T cg09795085 chr6:101329169 ASCC3 -0.47 -6.86 -0.35 3.28e-11 Neuroticism; LIHC cis rs8017423 0.967 rs7147952 chr14:90720831 G/A cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 3e-9 Mortality in heart failure; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.59 8.46 0.42 7.75e-16 Lymphocyte counts; LIHC cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg21724239 chr8:58056113 NA 0.57 7.02 0.35 1.22e-11 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg24549020 chr5:56110836 MAP3K1 0.51 6.4 0.33 5.12e-10 Initial pursuit acceleration; LIHC cis rs986417 0.901 rs2350901 chr14:60948128 A/G cg27398547 chr14:60952738 C14orf39 0.8 8.98 0.44 1.86e-17 Gut microbiota (bacterial taxa); LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.12 0.36 6.59e-12 Renal cell carcinoma; LIHC cis rs477692 0.699 rs578932 chr10:131370724 C/A cg05714579 chr10:131428358 MGMT 0.43 7.07 0.36 8.77e-12 Response to temozolomide; LIHC cis rs2635047 1.000 rs2277717 chr18:44702718 C/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.46 6.08 0.31 3.29e-9 Educational attainment; LIHC cis rs62458065 0.925 rs10243243 chr7:32460709 A/G cg06627557 chr7:32535165 LSM5;AVL9 -0.66 -7.29 -0.37 2.22e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs12980942 0.630 rs7256856 chr19:41788352 A/G cg25627403 chr19:41769009 HNRNPUL1 0.5 6.29 0.32 9.54e-10 Coronary artery disease; LIHC cis rs12644436 0.602 rs4082043 chr4:88780140 C/T cg06891869 chr4:88767617 MEPE 0.43 7.59 0.38 3.12e-13 HIV-1 viral setpoint; LIHC cis rs950776 0.518 rs12914694 chr15:78814444 G/A cg22563815 chr15:78856949 CHRNA5 0.36 6.53 0.33 2.44e-10 Sudden cardiac arrest; LIHC cis rs7223966 0.921 rs6504186 chr17:61863932 G/A cg05941027 chr17:61774174 LIMD2 0.35 7.35 0.37 1.48e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2257205 0.667 rs9893027 chr17:56653448 G/C cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg05665937 chr4:1216051 CTBP1 0.44 5.71 0.3 2.42e-8 Obesity-related traits; LIHC cis rs6815814 0.950 rs5743595 chr4:38802644 A/G cg06935464 chr4:38784597 TLR10 0.49 7.53 0.38 4.47e-13 Breast cancer; LIHC cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg11644478 chr21:40555479 PSMG1 0.41 6.58 0.34 1.79e-10 Cognitive function; LIHC cis rs1371867 0.846 rs1660330 chr8:101305015 T/A cg06636551 chr8:101224915 SPAG1 -0.5 -9.06 -0.44 1.02e-17 Atrioventricular conduction; LIHC cis rs9733 0.596 rs6685702 chr1:150656307 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Tonsillectomy; LIHC cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg06634786 chr22:41940651 POLR3H 0.82 9.06 0.44 1.02e-17 Vitiligo; LIHC cis rs7191439 0.858 rs4238685 chr16:88775220 T/C cg02389323 chr16:88786976 FAM38A 0.84 6.37 0.33 6.05e-10 Plateletcrit; LIHC cis rs9326248 1.000 rs4938354 chr11:117051165 A/G cg26566898 chr11:117069891 TAGLN 0.49 7.68 0.38 1.71e-13 Blood protein levels; LIHC cis rs4268898 0.662 rs72793967 chr2:24422902 C/T cg06627628 chr2:24431161 ITSN2 -0.73 -9.65 -0.46 1.23e-19 Asthma; LIHC cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg10360139 chr7:1886902 MAD1L1 -0.4 -6.19 -0.32 1.74e-9 Bipolar disorder and schizophrenia; LIHC cis rs6942756 0.876 rs28636722 chr7:129015151 C/T cg02491457 chr7:128862824 NA -0.58 -8.81 -0.43 6.35e-17 White matter hyperintensity burden; LIHC cis rs4665809 0.838 rs6546749 chr2:26306288 T/C cg04944784 chr2:26401820 FAM59B -0.68 -8.56 -0.42 3.77e-16 Gut microbiome composition (summer); LIHC cis rs875971 0.862 rs2088653 chr7:65808608 G/A cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs2016586 0.965 rs5995162 chr22:36118936 T/C cg26342177 chr22:36113512 APOL5 -0.38 -6.18 -0.32 1.78e-9 Body mass index; LIHC cis rs921968 0.613 rs556497 chr2:219446477 G/A cg02985541 chr2:219472218 PLCD4 0.44 8.5 0.42 5.86e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 0.688 rs113940455 chr3:10014165 A/C cg08888203 chr3:10149979 C3orf24 0.5 6.37 0.33 6.27e-10 Alzheimer's disease; LIHC cis rs311392 0.525 rs2013503 chr8:55104343 C/T cg11783602 chr8:55087084 NA -0.31 -6.23 -0.32 1.37e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs6933660 0.800 rs2046371 chr6:151754744 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.47 -6.97 -0.35 1.66e-11 Menarche (age at onset); LIHC cis rs425277 0.583 rs10910046 chr1:2041155 C/T cg04315214 chr1:2043799 PRKCZ 0.36 5.88 0.3 9.91e-9 Height; LIHC cis rs7845219 0.544 rs4735331 chr8:95917958 C/T cg13393036 chr8:95962371 TP53INP1 -0.32 -6.19 -0.32 1.69e-9 Type 2 diabetes; LIHC cis rs523522 0.923 rs3916065 chr12:120934624 A/C cg27279351 chr12:120934652 DYNLL1 0.67 12.05 0.55 3.99e-28 High light scatter reticulocyte count; LIHC trans rs916888 0.610 rs199453 chr17:44800946 C/T cg22968622 chr17:43663579 NA 0.49 7.09 0.36 7.83e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11098499 0.697 rs28458294 chr4:120238924 T/C cg09307838 chr4:120376055 NA 0.72 11.19 0.52 5.63e-25 Corneal astigmatism; LIHC cis rs17685 0.671 rs10274404 chr7:75706634 G/A cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.87e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.76 -0.34 6e-11 Gut microbiome composition (summer); LIHC trans rs4843747 0.671 rs8053377 chr16:88106465 A/G cg26811252 chr16:29126840 RRN3P2 0.41 6.67 0.34 1.02e-10 Menopause (age at onset); LIHC cis rs290268 0.874 rs290991 chr9:93561450 A/C cg02608019 chr9:93564028 SYK -0.35 -5.72 -0.3 2.28e-8 Platelet count; LIHC cis rs2370759 1.000 rs79578760 chr10:32611264 C/A cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.596 rs6587518 chr1:150661787 T/C cg18016565 chr1:150552671 MCL1 0.59 11.56 0.53 2.57e-26 Tonsillectomy; LIHC cis rs7131987 1.000 rs7131987 chr12:29406488 G/T cg05697976 chr12:29376483 FAR2 0.33 6.73 0.34 7.09e-11 QT interval; LIHC cis rs61774743 0.681 rs10749805 chr1:41850182 C/T cg03962019 chr1:41807865 NA -0.33 -5.76 -0.3 1.87e-8 Intelligence (multi-trait analysis); LIHC cis rs7572733 0.515 rs1518368 chr2:198839145 G/A cg03934865 chr2:198174659 NA 0.45 6.52 0.33 2.5e-10 Dermatomyositis; LIHC cis rs910316 0.673 rs2012627 chr14:75443103 C/T cg11812906 chr14:75593930 NEK9 0.72 13.62 0.59 4.85e-34 Height; LIHC trans rs71435601 0.943 rs71435593 chr2:21302020 T/C cg01780092 chr15:83380063 AP3B2 0.61 6.14 0.32 2.25e-9 Cholesterol, total; LIHC cis rs2573652 1.000 rs2581358 chr15:100513725 C/G cg09918751 chr15:100517450 ADAMTS17 -0.82 -14.85 -0.63 7.7e-39 Height; LIHC cis rs17152411 0.895 rs7079416 chr10:126587312 C/G cg07906193 chr10:126599966 NA 0.42 6.61 0.34 1.48e-10 Height; LIHC cis rs2070488 0.965 rs13097628 chr3:38521156 T/C cg24069376 chr3:38537580 EXOG 0.43 8.0 0.4 1.98e-14 Electrocardiographic conduction measures; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23849483 chr19:15224544 SYDE1 0.44 6.42 0.33 4.69e-10 Longevity; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg26338869 chr17:61819248 STRADA 0.62 8.97 0.44 2.01e-17 Prudent dietary pattern; LIHC cis rs858239 0.670 rs6967526 chr7:23159241 C/A cg23682824 chr7:23144976 KLHL7 0.41 6.33 0.32 7.85e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.72 10.54 0.5 1.14e-22 Lymphocyte counts; LIHC cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg11644478 chr21:40555479 PSMG1 0.79 9.9 0.47 1.7e-20 Cognitive function; LIHC cis rs8017423 0.904 rs2149647 chr14:90769539 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -14.13 -0.61 5.04e-36 Mortality in heart failure; LIHC cis rs1843834 0.505 rs4674911 chr2:225345254 A/G cg12698349 chr2:225449008 CUL3 0.69 10.71 0.5 2.95e-23 IgE levels in asthmatics (D.p. specific); LIHC cis rs365132 0.846 rs353470 chr5:176444861 C/T cg16309518 chr5:176445507 NA -0.53 -9.9 -0.47 1.79e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs6570726 0.791 rs6913727 chr6:145899826 A/G cg05347473 chr6:146136440 FBXO30 0.38 5.89 0.3 9.44e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2832191 0.740 rs6516890 chr21:30476812 T/A cg24692254 chr21:30365293 RNF160 0.7 12.88 0.57 3.32e-31 Dental caries; LIHC cis rs9858542 0.953 rs7646366 chr3:49470668 G/A cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg05484376 chr2:27715224 FNDC4 0.36 6.18 0.32 1.8e-9 Total body bone mineral density; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.75 -0.34 6.23e-11 Total body bone mineral density; LIHC cis rs34779708 0.966 rs2045917 chr10:35418526 G/A cg03585969 chr10:35415529 CREM 0.87 13.13 0.58 3.75e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6088813 1.000 rs6579234 chr20:33983485 A/G cg14752227 chr20:34000481 UQCC -0.4 -5.75 -0.3 1.99e-8 Height; LIHC cis rs250677 0.687 rs250664 chr5:148453823 C/T cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC trans rs11689435 0.925 rs1478593 chr2:218346137 G/A cg13544946 chr9:35729779 TLN1 -0.44 -6.35 -0.32 6.82e-10 Metabolite levels (MHPG); LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg21747090 chr2:27597821 SNX17 -0.42 -6.16 -0.32 2.02e-9 Total body bone mineral density; LIHC cis rs58688157 0.705 rs7122021 chr11:595810 A/G cg16486109 chr11:613632 IRF7 0.58 6.23 0.32 1.36e-9 Systemic lupus erythematosus; LIHC cis rs7617773 0.514 rs11130166 chr3:48388056 A/G cg11946769 chr3:48343235 NME6 0.6 7.36 0.37 1.37e-12 Coronary artery disease; LIHC cis rs1801251 1.000 rs6717841 chr2:233590255 C/T cg25237894 chr2:233734115 C2orf82 0.57 11.02 0.51 2.22e-24 Coronary artery disease; LIHC cis rs79149102 0.579 rs28394281 chr15:75326754 C/G cg09165964 chr15:75287851 SCAMP5 -0.6 -8.17 -0.4 5.84e-15 Lung cancer; LIHC trans rs6934970 0.860 rs12194046 chr6:112989209 A/G cg09308777 chr6:169852575 NA -0.68 -6.29 -0.32 9.73e-10 Bipolar disorder (body mass index interaction); LIHC cis rs10849605 1.000 rs10849605 chr12:1064438 C/T cg22937753 chr12:1022477 RAD52 0.38 7.36 0.37 1.35e-12 Lung cancer; LIHC cis rs2839186 0.500 rs13049893 chr21:47707054 C/T cg12516959 chr21:47718080 NA -0.4 -6.21 -0.32 1.56e-9 Testicular germ cell tumor; LIHC cis rs2439831 0.850 rs10438303 chr15:44016417 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.69 0.34 8.9e-11 Lung cancer in ever smokers; LIHC trans rs62103177 0.608 rs8088089 chr18:77832154 A/G cg05926928 chr17:57297772 GDPD1 -0.63 -7.04 -0.36 1.04e-11 Opioid sensitivity; LIHC cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg27170947 chr2:26402098 FAM59B 0.67 8.38 0.41 1.38e-15 Gut microbiome composition (summer); LIHC cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg04267008 chr7:1944627 MAD1L1 -0.68 -11.02 -0.51 2.36e-24 Bipolar disorder and schizophrenia; LIHC cis rs7312933 1.000 rs11181328 chr12:42504679 T/G cg17420585 chr12:42539391 GXYLT1 -0.37 -5.96 -0.31 6.3e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs116095464 0.558 rs10068203 chr5:206618 C/T cg22857025 chr5:266934 NA -1.65 -16.58 -0.67 9.67e-46 Breast cancer; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.85e-9 Menopause (age at onset); LIHC cis rs9303401 0.659 rs34818467 chr17:56643109 C/T cg25039879 chr17:56429692 SUPT4H1 -0.73 -9.39 -0.45 8.74e-19 Cognitive test performance; LIHC cis rs11644362 0.966 rs976011 chr16:12992910 C/T cg06890432 chr16:12997467 SHISA9 -0.39 -6.59 -0.34 1.64e-10 Positive affect;Subjective well-being; LIHC cis rs8014204 0.587 rs6574201 chr14:75387256 T/C cg08847533 chr14:75593920 NEK9 -0.44 -7.11 -0.36 7.01e-12 Caffeine consumption; LIHC cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg24549020 chr5:56110836 MAP3K1 0.51 6.57 0.33 1.91e-10 Initial pursuit acceleration; LIHC cis rs546131 0.614 rs35264793 chr11:34834844 G/C cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.59 -0.34 1.66e-10 Lung disease severity in cystic fibrosis; LIHC cis rs12135062 0.851 rs2651925 chr1:3101863 C/G cg21609526 chr1:3105151 PRDM16 0.25 5.78 0.3 1.73e-8 Migraine; LIHC cis rs600626 0.588 rs11236526 chr11:75467605 G/A cg24262691 chr11:75473276 NA 0.44 6.56 0.33 2.02e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC trans rs62103177 0.810 rs62103178 chr18:77624555 C/G cg05926928 chr17:57297772 GDPD1 1.1 11.28 0.52 2.73e-25 Opioid sensitivity; LIHC cis rs116095464 0.558 rs10057299 chr5:242135 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.7 -0.5 3.15e-23 Breast cancer; LIHC cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg22029157 chr1:209979665 IRF6 0.49 7.93 0.39 3.04e-14 Cleft lip with or without cleft palate; LIHC cis rs703842 0.532 rs238516 chr12:58117355 T/C cg18357645 chr12:58087776 OS9 0.48 8.08 0.4 1.12e-14 Multiple sclerosis; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.75 0.57 1.04e-30 Prudent dietary pattern; LIHC trans rs6489882 0.703 rs11066452 chr12:113361574 G/T cg10175203 chr3:128143634 NA 0.4 6.41 0.33 4.85e-10 Chronic lymphocytic leukemia; LIHC cis rs1005277 0.505 rs10827835 chr10:38150709 G/A cg00409905 chr10:38381863 ZNF37A 0.54 9.14 0.44 5.75e-18 Extrinsic epigenetic age acceleration; LIHC cis rs739401 0.619 rs10766481 chr11:2961512 G/C cg25174290 chr11:3078921 CARS 0.56 8.47 0.42 7.29e-16 Longevity; LIHC cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg12311346 chr5:56204834 C5orf35 -0.57 -7.46 -0.37 7.22e-13 Initial pursuit acceleration; LIHC cis rs67311347 1.000 rs6762997 chr3:40478151 C/T cg18306943 chr3:40428807 ENTPD3 0.33 5.88 0.3 9.6e-9 Renal cell carcinoma; LIHC cis rs1707322 0.682 rs28490344 chr1:46197948 C/T cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11098499 0.789 rs9991166 chr4:120237851 G/A cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg14671364 chr1:107599128 PRMT6 0.5 7.3 0.37 2.03e-12 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs67311347 1.000 rs977652 chr3:40479169 A/G cg00656387 chr3:40428638 ENTPD3 0.43 7.37 0.37 1.29e-12 Renal cell carcinoma; LIHC cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 3.96e-13 Electroencephalogram traits; LIHC cis rs798554 0.836 rs13243214 chr7:2817455 G/T cg04166393 chr7:2884313 GNA12 0.45 6.2 0.32 1.59e-9 Height; LIHC cis rs2832191 1.000 rs2832191 chr21:30489300 A/C cg08807101 chr21:30365312 RNF160 -0.59 -9.1 -0.44 7.62e-18 Dental caries; LIHC cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg16822855 chr3:40428330 ENTPD3 0.33 5.94 0.31 6.91e-9 Renal cell carcinoma; LIHC cis rs9768139 0.524 rs6459860 chr7:158136362 C/A cg25566285 chr7:158114605 PTPRN2 -0.22 -5.93 -0.31 7.54e-9 Calcium levels; LIHC cis rs9837602 0.507 rs793453 chr3:99529095 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.49 6.95 0.35 1.87e-11 Breast cancer; LIHC cis rs2455799 0.573 rs2062824 chr3:15757901 T/C cg12698662 chr3:15914712 MIR563 -0.4 -7.37 -0.37 1.28e-12 Mean platelet volume; LIHC cis rs67311347 1.000 rs6599094 chr3:40399593 A/G cg24209194 chr3:40518798 ZNF619 0.43 6.22 0.32 1.44e-9 Renal cell carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26348180 chr3:193852754 HES1 0.51 6.8 0.35 4.77e-11 Lung function (FEV1/FVC); LIHC cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg12310025 chr6:25882481 NA 0.86 11.79 0.54 3.63e-27 Blood metabolite levels; LIHC cis rs4788570 0.584 rs7204608 chr16:71678679 C/G cg06353428 chr16:71660113 MARVELD3 -1.08 -12.53 -0.56 6.79e-30 Intelligence (multi-trait analysis); LIHC cis rs899997 0.862 rs57260218 chr15:78973772 C/T cg04896959 chr15:78267971 NA -0.33 -6.04 -0.31 3.96e-9 Coronary artery disease or large artery stroke; LIHC cis rs2050392 0.965 rs2265368 chr10:30690289 G/C cg25182066 chr10:30743637 MAP3K8 -0.44 -7.19 -0.36 4.2e-12 Inflammatory bowel disease; LIHC cis rs66573146 0.539 rs56659624 chr4:7069377 G/C cg26116260 chr4:7069785 GRPEL1 -1.01 -12.32 -0.55 4.12e-29 Granulocyte percentage of myeloid white cells; LIHC cis rs644799 1.000 rs627568 chr11:95569253 A/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 16.83 0.67 9.95e-47 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1190552 0.761 rs4900536 chr14:102862994 A/G cg10241871 chr14:102965420 TECPR2 0.38 5.99 0.31 5.46e-9 Blood protein levels; LIHC cis rs2439831 0.850 rs28590651 chr15:44113016 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.55 6.69 0.34 9.15e-11 Lung cancer in ever smokers; LIHC cis rs651907 0.535 rs61396602 chr3:101509046 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.03 0.51 2.04e-24 Colorectal cancer; LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg01646665 chr1:156251436 TMEM79;SMG5 0.3 5.84 0.3 1.22e-8 Tonsillectomy; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg04519895 chr17:42785931 DBF4B -0.4 -6.12 -0.31 2.59e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs4253772 0.591 rs7291444 chr22:46656246 T/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.71 6.42 0.33 4.56e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs2806561 0.704 rs1757039 chr1:23508657 A/G cg19743168 chr1:23544995 NA 0.34 5.72 0.3 2.33e-8 Height; LIHC cis rs2637266 0.685 rs2395427 chr10:78462535 G/A cg18941641 chr10:78392320 NA 0.27 5.79 0.3 1.61e-8 Pulmonary function; LIHC cis rs912057 0.833 rs1294426 chr6:6744477 T/C cg06612196 chr6:6737390 NA 0.53 10.01 0.48 7.51e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg24879335 chr3:133465180 TF 0.29 6.47 0.33 3.49e-10 Iron status biomarkers; LIHC trans rs10411161 0.640 rs7252303 chr19:52389357 G/A cg22319618 chr22:45562946 NUP50 -0.62 -8.57 -0.42 3.59e-16 Breast cancer; LIHC cis rs4908768 0.871 rs11121221 chr1:8767529 A/G cg20416874 chr1:8611966 RERE 0.53 8.36 0.41 1.56e-15 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4478037 0.822 rs9883177 chr3:33123354 T/C cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.04 -0.36 1.05e-11 Major depressive disorder; LIHC cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg09467607 chr2:36825704 FEZ2 0.49 7.44 0.37 8.3e-13 Height; LIHC cis rs9910055 0.573 rs113184718 chr17:42206543 A/T cg16434002 chr17:42200994 HDAC5 0.54 7.77 0.39 9.14e-14 Total body bone mineral density; LIHC cis rs7412746 0.634 rs12096831 chr1:150864113 T/G cg15448220 chr1:150897856 SETDB1 0.42 6.62 0.34 1.42e-10 Melanoma; LIHC cis rs17750015 0.733 rs12454365 chr18:54396215 G/A cg18434998 chr18:54306185 TXNL1 -0.48 -6.64 -0.34 1.2e-10 Depression and alcohol dependence; LIHC trans rs2243480 0.522 rs1638736 chr7:66092308 A/T cg07424592 chr7:64974309 NA 0.78 8.31 0.41 2.26e-15 Diabetic kidney disease; LIHC cis rs1494950 1.000 rs10013449 chr4:15069589 G/A cg12377275 chr4:15005593 CPEB2 -0.88 -7.56 -0.38 3.77e-13 Political ideology; LIHC cis rs13126513 0.519 rs959247 chr4:100556984 A/G cg05468953 chr4:100565104 NA 0.31 6.11 0.31 2.77e-9 Metabolite levels (MHPG); LIHC cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg03806693 chr22:41940476 POLR3H 1.09 13.07 0.58 6.34e-32 Vitiligo; LIHC cis rs3096299 0.933 rs2965823 chr16:89454924 G/A cg08392591 chr16:89556376 ANKRD11 0.39 5.89 0.3 9.4e-9 Multiple myeloma (IgH translocation); LIHC trans rs61931739 0.500 rs7133447 chr12:34041901 A/G cg26384229 chr12:38710491 ALG10B 0.43 6.08 0.31 3.16e-9 Morning vs. evening chronotype; LIHC cis rs8067354 0.645 rs9901606 chr17:57811407 A/C cg13753209 chr17:57696993 CLTC 0.73 11.6 0.53 1.87e-26 Hemoglobin concentration; LIHC cis rs1395 0.922 rs1561535 chr2:27471025 C/T cg23587288 chr2:27483067 SLC30A3 -0.32 -6.11 -0.31 2.74e-9 Blood metabolite levels; LIHC cis rs1707322 0.721 rs61784796 chr1:46163256 A/G cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs801193 0.967 rs1110414 chr7:66205582 A/G cg11764359 chr7:65958608 NA 0.71 10.58 0.5 8.11e-23 Aortic root size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14929913 chr10:1147979 WDR37 -0.42 -6.33 -0.32 7.74e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg10802521 chr3:52805072 NEK4 -0.45 -7.4 -0.37 1.07e-12 Bipolar disorder; LIHC cis rs1371867 0.846 rs2047249 chr8:101234126 A/G cg06002616 chr8:101225028 SPAG1 0.35 6.03 0.31 4.34e-9 Atrioventricular conduction; LIHC cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -14.3 -0.61 1.06e-36 Alzheimer's disease; LIHC cis rs3008870 0.629 rs12742428 chr1:67426487 A/G cg02640540 chr1:67518911 SLC35D1 0.41 6.46 0.33 3.55e-10 Lymphocyte percentage of white cells; LIHC trans rs11098499 0.874 rs7661020 chr4:120106982 T/C cg25214090 chr10:38739885 LOC399744 0.45 7.28 0.37 2.35e-12 Corneal astigmatism; LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg00656387 chr3:40428638 ENTPD3 -0.51 -8.6 -0.42 2.86e-16 Renal cell carcinoma; LIHC cis rs7106204 0.609 rs11825384 chr11:24285137 G/T ch.11.24196551F chr11:24239977 NA 0.68 6.21 0.32 1.55e-9 Response to Homoharringtonine (cytotoxicity); LIHC cis rs7312933 0.703 rs10880259 chr12:42558003 T/C cg01256987 chr12:42539512 GXYLT1 -0.42 -7.03 -0.36 1.13e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1401999 0.714 rs7646621 chr3:183640865 A/C cg01324343 chr3:183735012 ABCC5 -0.53 -8.42 -0.41 1.04e-15 Anterior chamber depth; LIHC cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg18357526 chr6:26021779 HIST1H4A 0.95 12.87 0.57 3.44e-31 Intelligence (multi-trait analysis); LIHC cis rs6750795 0.746 rs2916579 chr2:232421159 A/G cg19187155 chr2:232395269 NMUR1 0.57 8.57 0.42 3.71e-16 Height; LIHC cis rs7044106 0.762 rs1411158 chr9:123464804 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.82 0.39 6.47e-14 Hip circumference adjusted for BMI; LIHC cis rs2274273 0.554 rs3742564 chr14:55530120 C/T cg01864836 chr14:55583639 NA 0.38 6.3 0.32 9.25e-10 Protein biomarker; LIHC cis rs798554 0.591 rs1182193 chr7:2869240 A/G cg13628971 chr7:2884303 GNA12 0.39 5.89 0.3 9.27e-9 Height; LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg05185784 chr16:90016020 DEF8 -0.48 -6.39 -0.33 5.56e-10 Skin colour saturation; LIHC cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.98 0.31 5.74e-9 Menopause (age at onset); LIHC cis rs4474465 1.000 rs7935292 chr11:78169885 C/G cg02023728 chr11:77925099 USP35 0.32 5.84 0.3 1.18e-8 Alzheimer's disease (survival time); LIHC cis rs151997 0.924 rs32480 chr5:50208099 G/A cg06027927 chr5:50259733 NA 0.57 7.72 0.39 1.31e-13 Callous-unemotional behaviour; LIHC cis rs3204270 0.500 rs62077175 chr17:79649568 G/T cg18367735 chr17:79674897 NA 0.68 7.84 0.39 5.88e-14 Dental caries; LIHC cis rs8180040 0.701 rs11917474 chr3:47010491 G/A cg16586182 chr3:47516702 SCAP -0.47 -8.5 -0.42 6.1e-16 Colorectal cancer; LIHC cis rs12594515 1.000 rs11855509 chr15:45995474 C/T cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs2380220 0.808 rs2716072 chr6:95909773 A/G cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs7412746 0.658 rs2275235 chr1:150730279 A/G cg18016565 chr1:150552671 MCL1 0.54 10.05 0.48 5.25e-21 Melanoma; LIHC cis rs739401 0.611 rs7394974 chr11:3038868 C/T cg25174290 chr11:3078921 CARS 0.62 9.47 0.46 4.77e-19 Longevity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25937148 chr3:43147320 C3orf39 0.6 8.01 0.4 1.78e-14 Lung function (FEV1/FVC); LIHC cis rs17666538 0.585 rs1669615 chr8:616665 T/C cg23958373 chr8:599963 NA 0.77 5.9 0.3 8.85e-9 IgG glycosylation; LIHC cis rs60871478 0.645 rs111968669 chr7:856683 C/T cg05535760 chr7:792225 HEATR2 -0.64 -7.49 -0.38 6.02e-13 Cerebrospinal P-tau181p levels; LIHC cis rs6598955 0.670 rs6598942 chr1:26531034 C/T cg04990556 chr1:26633338 UBXN11 -0.57 -9.11 -0.44 7.15e-18 Obesity-related traits; LIHC trans rs637571 0.522 rs503524 chr11:65751764 C/T cg17712092 chr4:129076599 LARP1B 0.74 13.11 0.58 4.34e-32 Eosinophil percentage of white cells; LIHC trans rs2262909 0.925 rs56073035 chr19:22276298 C/G cg17074339 chr11:11642133 GALNTL4 0.45 7.11 0.36 6.86e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs400736 0.894 rs225092 chr1:8036075 G/C cg25007680 chr1:8021821 PARK7 0.6 9.61 0.46 1.59e-19 Response to antidepressants and depression; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12863373 chr8:27695096 PBK 0.45 6.17 0.32 1.98e-9 Pancreatic cancer; LIHC cis rs7542375 0.524 rs2807869 chr1:221094068 A/G cg16008148 chr1:221062819 NA 0.3 6.53 0.33 2.36e-10 Obesity-related traits; LIHC cis rs9309473 0.950 rs10207264 chr2:73714097 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.66 -0.34 1.12e-10 Metabolite levels; LIHC cis rs11758351 1.000 rs76329209 chr6:26196430 A/G cg16070018 chr6:26224392 HIST1H3E 0.57 6.81 0.35 4.47e-11 Gout;Renal underexcretion gout; LIHC cis rs7927592 0.913 rs7109294 chr11:68332093 A/G cg16797656 chr11:68205561 LRP5 0.5 7.82 0.39 6.67e-14 Total body bone mineral density; LIHC cis rs11098499 0.697 rs35280960 chr4:120257059 G/A cg09307838 chr4:120376055 NA 0.69 10.34 0.49 5.64e-22 Corneal astigmatism; LIHC cis rs875971 0.862 rs1983372 chr7:65611351 C/T cg18876405 chr7:65276391 NA -0.38 -6.69 -0.34 9.03e-11 Aortic root size; LIHC cis rs8062405 1.000 rs12444171 chr16:28845251 G/A cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs10411161 0.702 rs7250193 chr19:52385520 C/T cg22319618 chr22:45562946 NUP50 0.59 8.03 0.4 1.58e-14 Breast cancer; LIHC cis rs7666738 0.830 rs13124127 chr4:98990729 G/A cg05340658 chr4:99064831 C4orf37 0.71 12.91 0.57 2.57e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs11190604 0.673 rs10883498 chr10:102228709 T/A cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7264396 0.790 rs6058283 chr20:34216276 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -9.91 -0.47 1.62e-20 Total cholesterol levels; LIHC cis rs11608355 0.545 rs11066782 chr12:109910552 C/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs7106204 0.590 rs7115417 chr11:24247696 A/G ch.11.24196551F chr11:24239977 NA 0.81 11.02 0.51 2.23e-24 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6089584 0.888 rs2146853 chr20:60617908 A/T cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.85e-26 Platelet count; LIHC cis rs9790314 0.846 rs9809522 chr3:160983768 G/C cg03342759 chr3:160939853 NMD3 -0.82 -13.51 -0.59 1.31e-33 Morning vs. evening chronotype; LIHC cis rs7296418 0.961 rs12425850 chr12:123501972 T/C cg00376283 chr12:123451042 ABCB9 0.75 13.59 0.59 6.12e-34 Platelet count; LIHC cis rs11711311 0.955 rs7617313 chr3:113391740 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.35 -5.89 -0.3 9.4e-9 IgG glycosylation; LIHC cis rs4555082 0.915 rs2816632 chr14:105741355 C/T cg06808227 chr14:105710500 BRF1 0.6 8.58 0.42 3.42e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs910316 1.000 rs175449 chr14:75590846 A/T cg11812906 chr14:75593930 NEK9 -0.77 -15.14 -0.63 5.41e-40 Height; LIHC cis rs9868809 0.505 rs9811027 chr3:48725014 G/C cg00383909 chr3:49044727 WDR6 0.66 5.89 0.3 9.33e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs9790314 0.638 rs17236725 chr3:160637935 C/T cg03342759 chr3:160939853 NMD3 0.57 7.58 0.38 3.33e-13 Morning vs. evening chronotype; LIHC trans rs11098499 0.954 rs28429722 chr4:120300093 G/A cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs11112613 0.713 rs58066965 chr12:105952505 C/G cg03607813 chr12:105948248 NA 0.63 12.47 0.56 1.14e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs13118159 0.725 rs71614967 chr4:1341291 A/G cg16405210 chr4:1374714 KIAA1530 -0.58 -7.3 -0.37 2.05e-12 Longevity; LIHC cis rs1023500 1.000 rs1023499 chr22:42340582 T/C cg04733989 chr22:42467013 NAGA -0.51 -6.05 -0.31 3.75e-9 Schizophrenia; LIHC cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg07636037 chr3:49044803 WDR6 0.75 12.25 0.55 7.33e-29 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9733 0.596 rs2867301 chr1:150653795 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Tonsillectomy; LIHC cis rs77861329 1.000 rs1237830 chr3:52202820 T/C cg08692210 chr3:52188851 WDR51A 0.83 7.86 0.39 5.11e-14 Macrophage inflammatory protein 1b levels; LIHC trans rs1814175 0.817 rs7950856 chr11:49976394 C/T cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs10078 0.559 rs2671891 chr5:456386 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.76 10.04 0.48 6.09e-21 Fat distribution (HIV); LIHC cis rs748404 0.660 rs689767 chr15:43722077 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.11e-13 Lung cancer; LIHC cis rs801193 1.000 rs6958520 chr7:66151453 T/C cg14393609 chr7:65229607 NA 0.38 5.87 0.3 1.02e-8 Aortic root size; LIHC cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg13397359 chr6:42928475 GNMT 0.64 9.38 0.45 9.33e-19 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9916302 0.861 rs644173 chr17:37430519 T/C cg03013999 chr17:37608204 MED1 0.36 6.01 0.31 4.67e-9 Glomerular filtration rate (creatinine); LIHC cis rs28456 1 rs28456 chr11:61589481 A/G cg27386326 chr11:61587980 NA 0.72 15.17 0.63 4.31e-40 Bipolar disorder; LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg21747090 chr2:27597821 SNX17 -0.46 -7.0 -0.35 1.37e-11 Total body bone mineral density; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00480142 chr12:96046743 NA 0.4 6.5 0.33 2.8e-10 Longevity; LIHC cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg06697600 chr4:7070879 GRPEL1 -0.65 -10.5 -0.49 1.58e-22 Monocyte percentage of white cells; LIHC cis rs6450176 0.638 rs11746856 chr5:53291295 A/C ch.5.1024479R chr5:53302184 ARL15 -1.02 -19.14 -0.72 5.26e-56 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs713477 0.967 rs4243600 chr14:55910679 A/G cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.32e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs1003719 0.788 rs2040341 chr21:38489753 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.94 0.54 1.01e-27 Eye color traits; LIHC cis rs782590 0.935 rs6739513 chr2:55749902 G/A cg18811423 chr2:55921094 PNPT1 0.97 14.95 0.63 3.06e-39 Metabolic syndrome; LIHC trans rs3780486 0.505 rs10217267 chr9:33146528 T/C cg20290983 chr6:43655470 MRPS18A 0.83 15.32 0.64 1.09e-40 IgG glycosylation; LIHC trans rs1728785 1.000 rs12925177 chr16:68569645 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.51 -6.33 -0.32 7.89e-10 Ulcerative colitis; LIHC cis rs3008870 0.920 rs3008865 chr1:67402838 T/C cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC trans rs12752401 0.867 rs12751548 chr1:103067463 A/G cg03332897 chr19:740442 PALM -0.46 -6.19 -0.32 1.68e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.55 8.33 0.41 1.93e-15 Height; LIHC cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.47 6.65 0.34 1.16e-10 Bipolar disorder; LIHC cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg00166722 chr3:10149974 C3orf24 0.52 6.02 0.31 4.61e-9 Alzheimer's disease; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg18110333 chr6:292329 DUSP22 -0.57 -7.9 -0.39 3.76e-14 Menopause (age at onset); LIHC cis rs12611088 0.571 rs8110232 chr19:44027390 T/C cg13740135 chr19:44006432 PHLDB3 -0.41 -6.09 -0.31 3.07e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs1843834 0.539 rs6749402 chr2:225443901 T/G cg12698349 chr2:225449008 CUL3 0.68 10.34 0.49 5.33e-22 IgE levels in asthmatics (D.p. specific); LIHC cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg25894440 chr7:65020034 NA -0.52 -5.98 -0.31 5.56e-9 Diabetic kidney disease; LIHC cis rs60871478 0.730 rs62432226 chr7:792973 T/C cg27478167 chr7:817139 HEATR2 -0.51 -6.75 -0.34 6.36e-11 Cerebrospinal P-tau181p levels; LIHC cis rs748404 0.697 rs524547 chr15:43551023 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.43 6.64 0.34 1.2e-10 Lung cancer; LIHC cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.14 -17.38 -0.68 6.12e-49 Gut microbiome composition (summer); LIHC cis rs507080 0.961 rs642497 chr11:118550784 C/A cg04173919 chr11:118528438 PHLDB1 0.32 5.99 0.31 5.42e-9 Serum metabolite levels; LIHC cis rs9814567 0.702 rs9871226 chr3:134331466 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs67311347 0.577 rs11129870 chr3:40260406 G/A cg18306943 chr3:40428807 ENTPD3 0.38 6.33 0.32 7.63e-10 Renal cell carcinoma; LIHC cis rs9486719 1.000 rs12208884 chr6:96885572 G/A cg06623918 chr6:96969491 KIAA0776 -0.72 -7.15 -0.36 5.19e-12 Migraine;Coronary artery disease; LIHC cis rs7937890 0.967 rs963212 chr11:14324732 A/G cg19336497 chr11:14380999 RRAS2 0.39 6.68 0.34 9.64e-11 Mitochondrial DNA levels; LIHC cis rs921968 0.608 rs11678428 chr2:219352598 C/T cg18887096 chr2:219472410 PLCD4 0.37 6.42 0.33 4.6e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6952808 0.575 rs6950330 chr7:1953606 T/C cg20295408 chr7:1910781 MAD1L1 -0.51 -7.56 -0.38 3.81e-13 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs1534166 0.647 rs1464937 chr3:133536655 C/G cg27366882 chr3:133540807 NA -0.41 -6.86 -0.35 3.16e-11 Alcohol consumption (transferrin glycosylation); LIHC cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg02034447 chr16:89574710 SPG7 0.46 7.06 0.36 9.18e-12 Multiple myeloma (IgH translocation); LIHC cis rs3820500 0.543 rs1316011 chr1:117941924 C/T cg20383390 chr1:117909022 MAN1A2 0.45 5.82 0.3 1.39e-8 Pneumonia; LIHC cis rs10832963 1.000 rs10128711 chr11:18632984 A/G cg09201001 chr11:18656081 SPTY2D1 0.93 17.27 0.68 1.69e-48 Breast cancer; LIHC cis rs7107174 1.000 rs10899478 chr11:78052238 C/T cg02023728 chr11:77925099 USP35 0.43 8.34 0.41 1.8e-15 Testicular germ cell tumor; LIHC cis rs116095464 0.558 rs2162870 chr5:228129 G/A cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs9326248 1.000 rs664971 chr11:117070857 A/G cg10130564 chr11:117069849 TAGLN -0.37 -6.18 -0.32 1.81e-9 Blood protein levels; LIHC cis rs1538970 0.504 rs3790585 chr1:46023356 A/T cg06784218 chr1:46089804 CCDC17 0.41 6.34 0.32 7.23e-10 Platelet count; LIHC cis rs208520 0.837 rs208486 chr6:66926255 A/T cg07460842 chr6:66804631 NA -0.78 -8.48 -0.42 7.05e-16 Exhaled nitric oxide output; LIHC cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg03517284 chr6:25882590 NA 0.49 7.1 0.36 7.22e-12 Blood metabolite levels; LIHC cis rs1008375 0.966 rs7658240 chr4:17588950 A/G cg16339924 chr4:17578868 LAP3 -0.56 -7.28 -0.37 2.26e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg11494091 chr17:61959527 GH2 0.46 8.33 0.41 1.99e-15 Prudent dietary pattern; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg26383753 chr2:85199382 KCMF1 -0.5 -6.34 -0.32 7.11e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs17401966 0.838 rs7553228 chr1:10350438 G/C cg19773385 chr1:10388646 KIF1B -0.41 -7.44 -0.37 8.34e-13 Hepatocellular carcinoma; LIHC cis rs1816752 0.905 rs3818938 chr13:25029083 C/T cg02811702 chr13:24901961 NA 0.24 6.3 0.32 9e-10 Obesity-related traits; LIHC cis rs1577917 0.876 rs4618490 chr6:86518403 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.01 -0.31 4.71e-9 Response to antipsychotic treatment; LIHC cis rs782590 0.774 rs2627773 chr2:55900459 A/G cg03859395 chr2:55845619 SMEK2 0.78 13.38 0.59 3.98e-33 Metabolic syndrome; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg04234412 chr22:24373322 LOC391322 -0.72 -11.0 -0.51 2.7e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7587476 1.000 rs7587476 chr2:215653887 T/C cg04004882 chr2:215674386 BARD1 -0.52 -6.94 -0.35 1.98e-11 Neuroblastoma; LIHC cis rs11971779 0.584 rs6942519 chr7:139070090 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs6061231 0.916 rs58488796 chr20:60949050 G/C cg06026331 chr20:60912101 LAMA5 0.44 6.14 0.32 2.29e-9 Colorectal cancer; LIHC cis rs801193 1.000 rs2659889 chr7:66217112 A/G cg18876405 chr7:65276391 NA 0.43 7.37 0.37 1.26e-12 Aortic root size; LIHC cis rs7520050 0.966 rs12139630 chr1:46350935 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 5.98 0.31 5.71e-9 Red blood cell count;Reticulocyte count; LIHC cis rs8180040 1.000 rs4858888 chr3:47405305 C/T cg27129171 chr3:47204927 SETD2 -0.66 -11.42 -0.53 8.44e-26 Colorectal cancer; LIHC trans rs1814175 0.645 rs28538913 chr11:50040718 C/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC trans rs2749592 0.550 rs7081464 chr10:37883937 C/T cg17830980 chr10:43048298 ZNF37B 0.42 7.94 0.39 3.02e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6674176 0.561 rs7161 chr1:44438974 A/G cg12908607 chr1:44402522 ARTN 0.51 8.57 0.42 3.72e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs921968 0.565 rs1554622 chr2:219606218 T/G cg02985541 chr2:219472218 PLCD4 -0.36 -6.34 -0.32 7.29e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs16854884 0.526 rs7643341 chr3:143726980 C/T cg06585982 chr3:143692056 C3orf58 0.49 6.83 0.35 3.97e-11 Economic and political preferences (feminism/equality); LIHC cis rs225245 0.782 rs225272 chr17:33969911 T/C cg05299278 chr17:33885742 SLFN14 0.23 6.27 0.32 1.11e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs1577917 0.655 rs2842605 chr6:86335150 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.3 -0.41 2.51e-15 Response to antipsychotic treatment; LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg13409248 chr3:40428643 ENTPD3 0.48 8.18 0.4 5.67e-15 Renal cell carcinoma; LIHC cis rs12824058 0.831 rs12310049 chr12:130811260 C/G cg24229701 chr12:130821962 PIWIL1 0.44 6.78 0.34 5.4e-11 Menopause (age at onset); LIHC cis rs1035144 0.506 rs2371416 chr14:81275672 A/T cg06600135 chr14:81408086 NA -0.47 -7.97 -0.4 2.35e-14 Male sexual orientation; LIHC trans rs17685 0.753 rs2302438 chr7:75677065 C/A cg19862616 chr7:65841803 NCRNA00174 0.9 18.26 0.7 1.79e-52 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1577917 0.958 rs12196230 chr6:86519960 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.78 -0.3 1.73e-8 Response to antipsychotic treatment; LIHC cis rs2257205 0.588 rs7209327 chr17:56741834 A/G cg12560992 chr17:57184187 TRIM37 0.71 7.79 0.39 8.05e-14 Pancreatic cancer; LIHC cis rs10870270 1.000 rs7199 chr10:133769848 C/G cg17892150 chr10:133769511 PPP2R2D -0.69 -12.96 -0.57 1.66e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg23758822 chr17:41437982 NA 0.94 17.69 0.69 3.46e-50 Menopause (age at onset); LIHC cis rs2153535 0.541 rs6908504 chr6:8456778 A/G cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs60871478 0.730 rs13222476 chr7:826630 T/C cg00934597 chr7:893267 UNC84A 0.48 5.87 0.3 1.02e-8 Cerebrospinal P-tau181p levels; LIHC cis rs9457247 0.588 rs35171809 chr6:167432766 A/G cg07741184 chr6:167504864 NA 0.26 6.11 0.31 2.74e-9 Crohn's disease; LIHC cis rs690037 0.673 rs690573 chr3:16376440 G/T cg23474789 chr3:16306055 DPH3;OXNAD1 -0.6 -9.02 -0.44 1.38e-17 Optic nerve measurement (cup-to-disc ratio);Optic nerve measurement (cup area); LIHC cis rs9534288 0.830 rs1126364 chr13:46633394 C/G cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs6840360 0.615 rs4696290 chr4:152631472 A/G cg22705602 chr4:152727874 NA -0.38 -8.14 -0.4 7.31e-15 Intelligence (multi-trait analysis); LIHC cis rs8072100 0.807 rs2175290 chr17:45479917 C/A cg08085267 chr17:45401833 C17orf57 -0.55 -8.24 -0.41 3.6e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs4942242 0.617 rs9590778 chr13:44199007 C/G cg19169023 chr15:41853346 TYRO3 -0.52 -7.15 -0.36 5.3e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs2354432 1.000 rs6680778 chr1:146747153 T/C cg25205988 chr1:146714368 CHD1L 1.09 20.44 0.74 3.03e-61 Mitochondrial DNA levels; LIHC cis rs1552244 0.515 rs7613004 chr3:9999913 A/C cg21531657 chr3:10005747 TMEM111 0.39 5.88 0.3 9.77e-9 Alzheimer's disease; LIHC cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg21724239 chr8:58056113 NA 0.59 7.56 0.38 3.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.836 rs2260230 chr7:2822986 T/A cg19717773 chr7:2847554 GNA12 -0.41 -6.65 -0.34 1.14e-10 Height; LIHC cis rs2153535 0.580 rs9406170 chr6:8514153 T/C cg21535247 chr6:8435926 SLC35B3 0.63 8.22 0.41 4.32e-15 Motion sickness; LIHC cis rs986417 0.748 rs1955700 chr14:61046481 A/G cg27398547 chr14:60952738 C14orf39 0.71 8.29 0.41 2.67e-15 Gut microbiota (bacterial taxa); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23797200 chr17:40174494 NKIRAS2 -0.64 -9.01 -0.44 1.52e-17 Lung function (FEV1/FVC); LIHC cis rs6988636 1.000 rs6983795 chr8:124185296 T/C cg15893493 chr8:124194847 FAM83A 0.89 8.3 0.41 2.48e-15 Urinary uromodulin levels; LIHC cis rs1003719 0.715 rs2835647 chr21:38546773 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs10840133 1 rs10840133 chr11:8846369 G/A cg12365402 chr11:9010492 NRIP3 0.24 5.84 0.3 1.19e-8 Reticulocyte fraction of red cells; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg07725925 chr16:89976287 TCF25 0.44 6.03 0.31 4.15e-9 Skin colour saturation; LIHC cis rs11758351 0.660 rs77337633 chr6:26233610 T/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs1348850 0.651 rs1901826 chr2:178225266 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.79 12.36 0.56 2.9e-29 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1062177 1.000 rs12515762 chr5:151209922 G/T cg00977110 chr5:151150581 G3BP1 0.52 6.54 0.33 2.3e-10 Preschool internalizing problems; LIHC cis rs7238033 0.624 rs9967412 chr18:43308889 C/G cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs35306767 0.951 rs11253530 chr10:993729 T/C cg20503657 chr10:835505 NA 0.94 9.25 0.45 2.52e-18 Eosinophil percentage of granulocytes; LIHC cis rs7762018 0.769 rs7766146 chr6:170070135 A/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.2 0.32 1.64e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.28e-9 Menopause (age at onset); LIHC cis rs9303280 0.628 rs12939565 chr17:38038389 A/T cg11212589 chr17:38028394 ZPBP2 0.35 7.24 0.36 3e-12 Self-reported allergy; LIHC cis rs10847980 0.623 rs28681105 chr12:123875525 T/C cg00376283 chr12:123451042 ABCB9 0.63 6.61 0.34 1.5e-10 Adiponectin levels; LIHC cis rs9814567 1.000 rs6782563 chr3:134295959 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.93 0.31 7.23e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.18 -0.44 4.35e-18 Bipolar disorder; LIHC cis rs1008375 0.931 rs7435102 chr4:17571480 C/G cg02297831 chr4:17616191 MED28 0.47 6.93 0.35 2.14e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1419980 0.730 rs11054915 chr12:7777003 G/T cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC trans rs2710642 0.564 rs60144282 chr2:62843163 G/T cg23713900 chr18:615496 CLUL1 -0.24 -6.23 -0.32 1.4e-9 LDL cholesterol levels;LDL cholesterol; LIHC cis rs2842992 0.724 rs4709368 chr6:160204127 C/T cg16489826 chr6:160211363 TCP1;MRPL18 -0.46 -8.58 -0.42 3.26e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs28595532 0.545 rs17516512 chr4:119258491 T/C cg21605333 chr4:119757512 SEC24D 0.79 6.65 0.34 1.19e-10 Cannabis dependence symptom count; LIHC cis rs3213545 0.645 rs2859398 chr12:121479655 T/C cg02403541 chr12:121454288 C12orf43 0.48 8.0 0.4 1.9e-14 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs9918079 0.560 rs13147590 chr4:15621188 A/G cg24225360 chr4:15471699 CC2D2A 0.36 5.78 0.3 1.69e-8 Obesity-related traits; LIHC cis rs6429082 0.660 rs10737818 chr1:235542023 A/G cg26050004 chr1:235667680 B3GALNT2 -0.47 -7.04 -0.36 1.06e-11 Adiposity; LIHC cis rs240764 0.817 rs239238 chr6:101094880 G/T cg09795085 chr6:101329169 ASCC3 0.51 7.12 0.36 6.46e-12 Neuroticism; LIHC cis rs1371867 0.817 rs1660315 chr8:101332956 G/A cg06636551 chr8:101224915 SPAG1 -0.49 -9.03 -0.44 1.27e-17 Atrioventricular conduction; LIHC cis rs9640161 0.789 rs34311995 chr7:150059255 T/C cg10018233 chr7:150070692 REPIN1 0.66 12.17 0.55 1.44e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs10751667 0.621 rs10794348 chr11:939941 G/A cg10932868 chr11:921992 NA 0.38 7.31 0.37 1.87e-12 Alzheimer's disease (late onset); LIHC cis rs929354 0.713 rs10085650 chr7:156993413 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs6430585 0.528 rs16832440 chr2:136754183 G/A cg25344623 chr2:136566232 LCT -0.37 -5.99 -0.31 5.43e-9 Corneal structure; LIHC cis rs1789 0.839 rs9997068 chr4:15650990 T/C cg21329975 chr4:15471214 CC2D2A -0.42 -6.33 -0.32 7.71e-10 Blood protein levels; LIHC cis rs2197308 0.740 rs11182967 chr12:37935140 A/C cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg04944784 chr2:26401820 FAM59B -0.71 -9.3 -0.45 1.7e-18 Gut microbiome composition (summer); LIHC cis rs6088590 1.000 rs55753039 chr20:33394940 C/T cg24642439 chr20:33292090 TP53INP2 0.76 10.35 0.49 5.09e-22 Coronary artery disease; LIHC cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg11764359 chr7:65958608 NA 0.57 5.99 0.31 5.32e-9 Diabetic kidney disease; LIHC cis rs7927592 0.701 rs12226585 chr11:68257861 A/T cg16797656 chr11:68205561 LRP5 -0.52 -9.14 -0.44 5.5e-18 Total body bone mineral density; LIHC cis rs965469 0.843 rs6139122 chr20:3395871 T/G cg25506879 chr20:3388711 C20orf194 -0.54 -6.29 -0.32 9.48e-10 IFN-related cytopenia; LIHC cis rs9916302 0.706 rs590051 chr17:37446571 T/C cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs2033908 0.620 rs7113256 chr11:12845849 T/C cg25843174 chr11:12811716 TEAD1 -0.34 -7.55 -0.38 4.02e-13 Sitting height ratio; LIHC cis rs677665 0.537 rs6688233 chr1:9335745 A/G cg25755851 chr1:9335794 NA -0.68 -11.25 -0.52 3.46e-25 Eosinophil percentage of white cells; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg23681251 chr19:48202226 GLTSCR1 0.39 6.39 0.33 5.53e-10 Bipolar disorder; LIHC cis rs10791323 0.569 rs2156680 chr11:133742292 T/G cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.58e-9 Childhood ear infection; LIHC trans rs11098499 0.866 rs13125526 chr4:120288019 G/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC trans rs7504990 0.802 rs752870 chr18:50386335 C/T cg08535148 chr4:26321143 RBPJ 0.52 6.2 0.32 1.61e-9 Gallbladder cancer; LIHC cis rs2737618 0.722 rs2737680 chr1:200088559 C/A cg21825944 chr1:200113062 NR5A2 -0.49 -8.33 -0.41 2.02e-15 Uric acid levels; LIHC cis rs861020 0.771 rs661849 chr1:210001233 C/T cg05527609 chr1:210001259 C1orf107 1.0 15.19 0.63 3.59e-40 Orofacial clefts; LIHC cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg11062466 chr8:58055876 NA 0.47 6.41 0.33 4.89e-10 Developmental language disorder (linguistic errors); LIHC cis rs4555082 0.915 rs79048296 chr14:105754944 G/A cg10792982 chr14:105748885 BRF1 0.44 6.0 0.31 5.16e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs7772486 0.790 rs1854900 chr6:146331382 G/A cg05347473 chr6:146136440 FBXO30 0.37 6.05 0.31 3.74e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1976403 0.510 rs1697421 chr1:21823292 C/T cg18541006 chr1:21754153 NA -0.29 -6.7 -0.34 8.55e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs12220238 1.000 rs10824102 chr10:75948915 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.35 0.32 7e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7208859 0.623 rs216436 chr17:28922900 G/A cg14067834 chr17:29058358 SUZ12P 0.68 6.7 0.34 8.55e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7772486 0.713 rs1986729 chr6:146194831 G/A cg05347473 chr6:146136440 FBXO30 0.38 6.05 0.31 3.88e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2573652 1.000 rs2727199 chr15:100514417 C/T cg09918751 chr15:100517450 ADAMTS17 -0.84 -15.72 -0.65 2.73e-42 Height; LIHC trans rs11165623 0.564 rs9887887 chr1:96996930 A/G cg10631902 chr5:14652156 NA -0.29 -6.77 -0.34 5.62e-11 Hip circumference;Waist circumference; LIHC cis rs903552 0.932 rs2172851 chr15:102012626 C/T cg25677261 chr15:102009856 PCSK6 -0.48 -6.43 -0.33 4.28e-10 Diabetic kidney disease; LIHC cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg09222892 chr1:25734099 RHCE -0.46 -8.24 -0.41 3.62e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs2842992 0.673 rs6930904 chr6:160217433 T/A cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.7 0.57 1.51e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs1865760 0.929 rs12195653 chr6:25958621 A/G cg17691542 chr6:26056736 HIST1H1C 0.39 5.83 0.3 1.27e-8 Height; LIHC cis rs79057730 0.599 rs4721086 chr7:821123 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.76 8.62 0.42 2.51e-16 Initial pursuit acceleration; LIHC trans rs3780486 0.846 rs6476402 chr9:33148552 G/A cg20290983 chr6:43655470 MRPS18A 1.04 21.39 0.76 4.82e-65 IgG glycosylation; LIHC cis rs9290065 0.519 rs956447 chr3:160668917 G/C cg03342759 chr3:160939853 NMD3 -0.46 -6.49 -0.33 3.1e-10 Kawasaki disease; LIHC cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg02187348 chr16:89574699 SPG7 0.52 7.57 0.38 3.53e-13 Multiple myeloma (IgH translocation); LIHC cis rs9325144 0.647 rs34311455 chr12:39060889 C/T cg26384229 chr12:38710491 ALG10B -0.41 -5.88 -0.3 9.55e-9 Morning vs. evening chronotype; LIHC cis rs4853036 1.000 rs34587942 chr2:70081501 G/A cg02498382 chr2:70120550 SNRNP27 -0.37 -5.94 -0.31 6.99e-9 Colorectal or endometrial cancer; LIHC cis rs3008870 1.000 rs3008848 chr1:67379284 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.6 0.67 8.6e-46 Lymphocyte percentage of white cells; LIHC cis rs1707322 1.000 rs11211248 chr1:46476844 A/G cg03146154 chr1:46216737 IPP 0.48 7.85 0.39 5.54e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs941408 1.000 rs1640273 chr19:2803227 C/T cg22153745 chr1:153894579 GATAD2B -0.41 -6.33 -0.32 7.79e-10 Total cholesterol levels; LIHC cis rs477692 0.673 rs1078847 chr10:131352115 T/C cg05714579 chr10:131428358 MGMT 0.4 6.46 0.33 3.7e-10 Response to temozolomide; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11688874 chr10:28822482 WAC 0.44 7.04 0.36 1.04e-11 Cognitive function; LIHC cis rs2637030 0.559 rs256107 chr5:52873776 C/T cg06476337 chr5:52856530 NDUFS4 0.43 6.79 0.34 5e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs7572733 0.534 rs700687 chr2:198721560 A/T cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs208520 0.690 rs12201219 chr6:66748862 A/T cg07460842 chr6:66804631 NA 0.78 9.07 0.44 9.76e-18 Exhaled nitric oxide output; LIHC trans rs6991952 0.702 rs12541705 chr8:25709710 A/C cg03796024 chr10:3151764 PFKP 0.35 6.21 0.32 1.5e-9 Inguinal hernia; LIHC cis rs1568889 1.000 rs7951681 chr11:28273894 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 7.05 0.36 9.97e-12 Bipolar disorder; LIHC cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg06466757 chr4:1255808 NA 0.34 5.79 0.3 1.61e-8 Obesity-related traits; LIHC cis rs79387448 0.576 rs11902044 chr2:102972534 C/T cg09003973 chr2:102972529 NA 1.17 9.75 0.47 5.68e-20 Gut microbiota (bacterial taxa); LIHC cis rs10911251 0.528 rs2093982 chr1:183094191 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Colorectal cancer; LIHC cis rs7208859 0.623 rs7219712 chr17:29080570 G/T cg14067834 chr17:29058358 SUZ12P 0.69 6.78 0.34 5.4e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2243480 0.901 rs34807232 chr7:65965133 G/A cg18252515 chr7:66147081 NA -1.29 -17.47 -0.69 2.78e-49 Diabetic kidney disease; LIHC cis rs12908161 1.000 rs17601029 chr15:85347709 A/G cg17507749 chr15:85114479 UBE2QP1 0.63 7.23 0.36 3.1e-12 Schizophrenia; LIHC cis rs5758659 0.716 rs86669 chr22:42680800 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.3 -5.86 -0.3 1.08e-8 Cognitive function; LIHC cis rs7412746 0.571 rs12402939 chr1:150615094 A/C cg15448220 chr1:150897856 SETDB1 0.43 6.75 0.34 6.28e-11 Melanoma; LIHC cis rs2073300 0.609 rs6137917 chr20:23360369 G/A cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.44 6.24 0.32 1.3e-9 Schizophrenia; LIHC cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg17747265 chr1:1875780 NA -0.58 -11.24 -0.52 3.64e-25 Body mass index; LIHC cis rs2274273 0.967 rs2340931 chr14:55616937 T/G cg01864836 chr14:55583639 NA -0.42 -8.04 -0.4 1.49e-14 Protein biomarker; LIHC cis rs68170813 0.559 rs79026644 chr7:107031803 A/G cg02696742 chr7:106810147 HBP1 -0.5 -5.73 -0.3 2.24e-8 Coronary artery disease; LIHC cis rs8078723 0.674 rs9303284 chr17:38205793 C/T cg17467752 chr17:38218738 THRA -0.83 -16.23 -0.66 2.56e-44 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.16 0.55 1.58e-28 Prudent dietary pattern; LIHC cis rs2153535 0.584 rs9502721 chr6:8541379 G/A cg23788917 chr6:8435910 SLC35B3 0.63 8.73 0.43 1.17e-16 Motion sickness; LIHC cis rs2455601 1.000 rs7104661 chr11:8902501 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.5 -6.51 -0.33 2.63e-10 Schizophrenia; LIHC cis rs6540556 0.723 rs9430016 chr1:209916884 A/G cg05527609 chr1:210001259 C1orf107 -0.55 -7.68 -0.38 1.72e-13 Red blood cell count; LIHC cis rs826838 0.967 rs1486345 chr12:39131677 G/A cg26384229 chr12:38710491 ALG10B -0.61 -8.64 -0.42 2.27e-16 Heart rate; LIHC cis rs62458065 0.513 rs787216 chr7:32578891 G/A cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -7.13 -0.36 5.88e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg00684032 chr4:1343700 KIAA1530 0.51 7.75 0.39 1.08e-13 Obesity-related traits; LIHC cis rs2180341 0.566 rs982306 chr6:127777039 T/C cg24812749 chr6:127587940 RNF146 0.76 10.76 0.5 1.89e-23 Breast cancer; LIHC cis rs12478296 0.901 rs59477854 chr2:243015490 T/C cg06360820 chr2:242988706 NA -0.79 -11.53 -0.53 3.29e-26 Obesity-related traits; LIHC cis rs10927875 0.864 rs1976402 chr1:16143779 G/A cg21385522 chr1:16154831 NA -1.05 -13.0 -0.57 1.17e-31 Dilated cardiomyopathy; LIHC cis rs77633900 0.614 rs280029 chr15:77031235 A/G cg21673338 chr15:77095150 SCAPER -0.5 -7.42 -0.37 9.3e-13 Non-glioblastoma glioma;Glioma; LIHC trans rs916888 0.821 rs415430 chr17:44859144 C/T cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs11098499 0.697 rs4560394 chr4:120313435 T/G cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 1.99e-16 Corneal astigmatism; LIHC cis rs9868809 1.000 rs9868809 chr3:48681053 C/T cg07636037 chr3:49044803 WDR6 -0.55 -5.97 -0.31 5.88e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs13217239 0.585 rs114919438 chr6:26963792 T/C cg18867708 chr6:26865862 GUSBL1 -0.51 -7.86 -0.39 4.96e-14 Schizophrenia; LIHC cis rs1008375 0.800 rs28754811 chr4:17612312 C/T cg16339924 chr4:17578868 LAP3 0.41 5.79 0.3 1.57e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2760061 0.655 rs686533 chr1:228119604 A/G cg01200585 chr1:228362443 C1orf69 -0.39 -5.85 -0.3 1.15e-8 Diastolic blood pressure; LIHC cis rs365132 0.846 rs184784 chr5:176440229 G/T cg16309518 chr5:176445507 NA -0.53 -9.89 -0.47 1.88e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs11212260 0.655 rs11212229 chr11:107301248 C/T cg25435332 chr11:107328525 CWF19L2 0.82 8.3 0.41 2.4e-15 IgG glycosylation; LIHC cis rs7937890 0.904 rs67623158 chr11:14295196 T/C cg02886208 chr11:14281011 SPON1 0.61 9.02 0.44 1.38e-17 Mitochondrial DNA levels; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg06656553 chr16:89960601 TCF25 -0.49 -6.21 -0.32 1.55e-9 Skin colour saturation; LIHC cis rs7772486 0.720 rs702320 chr6:146006654 G/A cg05347473 chr6:146136440 FBXO30 -0.37 -5.94 -0.31 6.93e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4638749 0.677 rs13398290 chr2:108833853 G/T cg06795125 chr2:108905320 SULT1C2 -0.29 -5.73 -0.3 2.21e-8 Blood pressure; LIHC cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg18305652 chr10:134549665 INPP5A 0.43 6.27 0.32 1.08e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1552244 0.882 rs55840655 chr3:10042690 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs4820539 0.708 rs5751591 chr22:23489042 G/A cg14186256 chr22:23484241 RTDR1 0.79 9.59 0.46 1.84e-19 Bone mineral density; LIHC cis rs2033711 0.905 rs1077420 chr19:58968875 A/C cg00825309 chr19:58991885 ZNF446 -0.69 -10.71 -0.5 2.72e-23 Uric acid clearance; LIHC cis rs5753618 0.561 rs13054220 chr22:31704492 A/G cg07713946 chr22:31675144 LIMK2 0.43 7.8 0.39 7.68e-14 Colorectal cancer; LIHC cis rs9640161 0.830 rs3735165 chr7:150068371 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -8.12 -0.4 8.55e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs3096299 0.967 rs2911257 chr16:89484134 C/G cg02187348 chr16:89574699 SPG7 0.48 7.06 0.36 9.42e-12 Multiple myeloma (IgH translocation); LIHC cis rs7727544 0.684 rs274561 chr5:131719228 A/C cg07395648 chr5:131743802 NA -0.31 -6.5 -0.33 2.84e-10 Blood metabolite levels; LIHC cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg25894440 chr7:65020034 NA -0.53 -6.2 -0.32 1.64e-9 Diabetic kidney disease; LIHC cis rs7095944 0.614 rs7099316 chr10:126469005 G/A cg20435097 chr10:126320824 FAM53B 0.38 6.42 0.33 4.64e-10 Asthma; LIHC cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg25364880 chr3:44379878 C3orf23 0.55 7.58 0.38 3.32e-13 Depressive symptoms; LIHC cis rs763121 0.853 rs138704 chr22:39133410 A/G cg14440974 chr22:39074834 NA -0.37 -6.32 -0.32 8.16e-10 Menopause (age at onset); LIHC cis rs11758351 0.866 rs56186759 chr6:26207181 C/T cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs151997 1.000 rs42736 chr5:50244838 G/C cg06027927 chr5:50259733 NA 0.6 7.94 0.39 2.93e-14 Callous-unemotional behaviour; LIHC cis rs1892700 1.000 rs1892700 chr21:35016137 G/A cg14850771 chr21:34775459 IFNGR2 -0.44 -5.86 -0.3 1.11e-8 Educational attainment; LIHC cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg11766577 chr21:47581405 C21orf56 -0.4 -6.25 -0.32 1.2e-9 Testicular germ cell tumor; LIHC cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg19723775 chr5:179050963 HNRNPH1 0.42 6.55 0.33 2.17e-10 Lung cancer; LIHC trans rs78049276 0.736 rs77028772 chr4:148364920 G/A cg13149281 chr14:23389818 RBM23;PRMT5 -0.61 -7.54 -0.38 4.36e-13 Pulse pressure; LIHC cis rs12579753 0.879 rs12829053 chr12:82161926 T/A cg07988820 chr12:82153109 PPFIA2 -0.52 -6.5 -0.33 2.76e-10 Resting heart rate; LIHC cis rs17052344 0.543 rs2342183 chr17:21738349 G/T cg18423549 chr17:21743878 NA -0.47 -6.04 -0.31 3.99e-9 Cutaneous psoriasis; LIHC cis rs2932538 0.922 rs12402469 chr1:113076625 G/A cg22162597 chr1:113214053 CAPZA1 0.69 10.65 0.5 4.73e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7618501 0.519 rs3774750 chr3:50208406 C/G cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.49 -7.24 -0.36 3.06e-12 Intelligence (multi-trait analysis); LIHC cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.05 0.44 1.13e-17 Platelet count; LIHC cis rs4478037 0.822 rs59834381 chr3:33116313 G/A cg27203090 chr3:33138513 GLB1;TMPPE -0.56 -6.94 -0.35 2.01e-11 Major depressive disorder; LIHC cis rs10751667 1.000 rs12798036 chr11:947585 T/C cg10932868 chr11:921992 NA 0.35 6.46 0.33 3.55e-10 Alzheimer's disease (late onset); LIHC cis rs9309473 0.950 rs6726694 chr2:73847230 A/G cg20560298 chr2:73613845 ALMS1 -0.51 -6.47 -0.33 3.46e-10 Metabolite levels; LIHC cis rs644799 1.000 rs557079 chr11:95530125 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.14 0.68 5.42e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg11060661 chr22:24314208 DDT;DDTL -0.58 -9.28 -0.45 1.94e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.59 0.56 4.16e-30 Total body bone mineral density; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08493051 chr2:3487164 NA 0.52 6.26 0.32 1.15e-9 Systolic blood pressure; LIHC cis rs1816752 0.806 rs3816218 chr13:25017171 A/G cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.81e-10 Obesity-related traits; LIHC cis rs8053891 0.615 rs2287997 chr16:72140553 G/A cg01557791 chr16:72042693 DHODH -0.53 -7.34 -0.37 1.57e-12 Coronary artery disease; LIHC cis rs796364 0.806 rs10445792 chr2:201078821 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.64 -6.74 -0.34 6.95e-11 Schizophrenia; LIHC cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg08392591 chr16:89556376 ANKRD11 0.52 8.31 0.41 2.27e-15 Multiple myeloma (IgH translocation); LIHC cis rs6430585 0.583 rs4988201 chr2:136618507 A/G cg07169764 chr2:136633963 MCM6 1.34 22.96 0.78 3.03e-71 Corneal structure; LIHC cis rs7523273 0.505 rs34277355 chr1:207881491 C/A cg22525895 chr1:207977042 MIR29B2 0.49 7.68 0.38 1.75e-13 Schizophrenia; LIHC trans rs5756813 0.646 rs3788528 chr22:38146433 T/C cg19894588 chr14:64061835 NA 0.43 6.31 0.32 8.55e-10 Optic cup area;Vertical cup-disc ratio; LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg07677032 chr17:61819896 STRADA 0.43 6.3 0.32 9.2e-10 Prudent dietary pattern; LIHC trans rs867371 1.000 rs1501372 chr15:82468455 C/T cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.1 -0.36 7.18e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs72781680 0.948 rs72796319 chr2:24133027 T/C cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs9325144 0.505 rs901635 chr12:38646572 A/C cg26384229 chr12:38710491 ALG10B -0.46 -7.19 -0.36 4.14e-12 Morning vs. evening chronotype; LIHC cis rs2455799 0.533 rs2470550 chr3:15743721 C/T cg12698662 chr3:15914712 MIR563 -0.36 -6.58 -0.34 1.72e-10 Mean platelet volume; LIHC cis rs7216064 0.953 rs4791046 chr17:65851973 G/A cg12091567 chr17:66097778 LOC651250 -0.64 -9.12 -0.44 6.43e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs765787 0.530 rs3759895 chr15:45543870 G/A cg25801113 chr15:45476975 SHF 0.37 6.24 0.32 1.28e-9 Uric acid levels; LIHC cis rs3106136 0.872 rs13130583 chr4:95245543 T/C cg11021082 chr4:95130006 SMARCAD1 0.41 7.27 0.37 2.51e-12 Capecitabine sensitivity; LIHC cis rs1494950 0.661 rs2643084 chr4:14998608 T/C cg12377275 chr4:15005593 CPEB2 -0.79 -6.68 -0.34 9.6e-11 Political ideology; LIHC cis rs10870270 0.956 rs6557 chr10:133781449 C/T cg08754478 chr10:133766260 PPP2R2D -0.55 -8.08 -0.4 1.11e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10193935 0.901 rs92303 chr2:42656337 A/G cg27598129 chr2:42591480 NA 0.68 10.11 0.48 3.43e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs7618501 1.000 rs11709680 chr3:49745188 C/T cg24110177 chr3:50126178 RBM5 0.43 6.66 0.34 1.08e-10 Intelligence (multi-trait analysis); LIHC cis rs798554 0.634 rs1182180 chr7:2873279 G/T cg19717773 chr7:2847554 GNA12 -0.4 -7.01 -0.35 1.27e-11 Height; LIHC cis rs1018836 0.886 rs12545351 chr8:91636668 C/T cg16814680 chr8:91681699 NA -0.63 -10.04 -0.48 5.66e-21 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7487075 0.619 rs7311504 chr12:46830776 G/A cg23829395 chr12:46796953 NA 0.34 6.02 0.31 4.6e-9 Itch intensity from mosquito bite; LIHC cis rs10751667 0.666 rs10902239 chr11:946484 A/G cg06064525 chr11:970664 AP2A2 0.56 15.15 0.63 5.17e-40 Alzheimer's disease (late onset); LIHC cis rs2380220 0.606 rs7747776 chr6:96005852 C/T cg15832292 chr6:96025679 MANEA 0.6 8.35 0.41 1.76e-15 Behavioural disinhibition (generation interaction); LIHC cis rs807669 0.903 rs807666 chr22:19160549 C/T cg02655711 chr22:19163373 SLC25A1 0.76 11.54 0.53 3.13e-26 Metabolite levels; LIHC cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg00343986 chr7:65444356 GUSB -0.43 -6.04 -0.31 4.03e-9 Aortic root size; LIHC cis rs7208859 0.673 rs9912122 chr17:29140716 C/A cg13385521 chr17:29058706 SUZ12P 0.8 8.19 0.4 5.35e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600806 0.888 rs2228604 chr1:109884775 A/C cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.8 -0.39 7.78e-14 Intelligence (multi-trait analysis); LIHC cis rs7635838 0.785 rs2574698 chr3:11557126 G/A cg00170343 chr3:11313890 ATG7 0.37 5.73 0.3 2.26e-8 HDL cholesterol; LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg06420487 chr17:61919686 SMARCD2 0.42 5.76 0.3 1.88e-8 Height; LIHC cis rs10744422 1.000 rs2292134 chr12:123334033 C/G cg22842854 chr12:123319900 HIP1R -0.74 -9.76 -0.47 5.03e-20 Schizophrenia; LIHC trans rs10242455 0.702 rs73403290 chr7:99157828 C/T cg09045935 chr12:6379348 NA 0.93 7.65 0.38 2.07e-13 Blood metabolite levels; LIHC cis rs9300255 0.602 rs1106240 chr12:123626982 C/T cg00376283 chr12:123451042 ABCB9 0.58 6.2 0.32 1.65e-9 Neutrophil percentage of white cells; LIHC cis rs7647973 1.000 rs6785045 chr3:49435243 G/C cg07636037 chr3:49044803 WDR6 -0.53 -6.44 -0.33 4.07e-10 Menarche (age at onset); LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.0 -0.31 5.01e-9 Diastolic blood pressure; LIHC trans rs1005277 0.522 rs289648 chr10:37971837 T/C cg17830980 chr10:43048298 ZNF37B -0.43 -8.24 -0.41 3.73e-15 Extrinsic epigenetic age acceleration; LIHC cis rs7546668 1.000 rs6695562 chr1:15842842 C/T cg11706911 chr1:15910989 AGMAT 0.45 6.96 0.35 1.7e-11 Glomerular filtration rate (creatinine); LIHC cis rs56146971 0.703 rs76533089 chr14:91863973 G/T cg16433844 chr14:91963127 SMEK1 -0.51 -5.84 -0.3 1.19e-8 Alzheimer disease and age of onset; LIHC cis rs7582720 0.943 rs72932560 chr2:203847417 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7647973 0.559 rs9586 chr3:49213637 C/T cg07636037 chr3:49044803 WDR6 0.51 6.29 0.32 9.43e-10 Menarche (age at onset); LIHC cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg04944784 chr2:26401820 FAM59B -0.72 -9.14 -0.44 5.77e-18 Gut microbiome composition (summer); LIHC cis rs2012796 0.665 rs72703728 chr14:81834523 G/A cg02996355 chr14:81879375 NA 0.75 12.01 0.54 5.98e-28 Night sleep phenotypes; LIHC cis rs4975616 0.869 rs401681 chr5:1322087 C/T cg07493874 chr5:1342172 CLPTM1L -0.52 -8.77 -0.43 8.8e-17 Lung cancer; LIHC cis rs8044995 0.563 rs1110572 chr16:68396119 A/G cg05110241 chr16:68378359 PRMT7 -0.85 -9.45 -0.45 5.58e-19 Schizophrenia; LIHC cis rs1577917 0.771 rs12199873 chr6:86294947 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.86 -0.39 4.92e-14 Response to antipsychotic treatment; LIHC cis rs1801251 0.893 rs11687128 chr2:233608901 T/C cg25237894 chr2:233734115 C2orf82 0.58 11.15 0.52 7.7e-25 Coronary artery disease; LIHC cis rs4555082 0.957 rs3825762 chr14:105752404 T/C cg06808227 chr14:105710500 BRF1 -0.62 -8.53 -0.42 4.97e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs11711311 0.955 rs34458493 chr3:113396473 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.34 5.87 0.3 1.05e-8 IgG glycosylation; LIHC cis rs853679 0.517 rs35512245 chr6:28079953 T/C cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs6964587 0.967 rs7788092 chr7:91646198 C/T cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg11764359 chr7:65958608 NA -0.69 -9.29 -0.45 1.84e-18 Calcium levels; LIHC cis rs11122272 0.735 rs2739510 chr1:231526718 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.25 -0.48 1.1e-21 Hemoglobin concentration; LIHC cis rs6701037 0.748 rs11585368 chr1:175135448 G/A cg00321850 chr1:175162397 KIAA0040 -0.46 -7.19 -0.36 4.15e-12 Alcohol dependence; LIHC cis rs16828019 0.704 rs34486565 chr1:41522510 C/T cg03962019 chr1:41807865 NA 0.49 7.06 0.36 9.32e-12 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs644799 1.000 rs566204 chr11:95580926 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.66 0.46 1.12e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs15676 0.679 rs6478853 chr9:131588813 C/G cg00228799 chr9:131580591 ENDOG -0.47 -6.91 -0.35 2.39e-11 Blood metabolite levels; LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg19635926 chr16:89946313 TCF25 0.54 7.2 0.36 3.9e-12 Skin colour saturation; LIHC cis rs5769765 0.908 rs9616211 chr22:50317676 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.76 -9.5 -0.46 3.87e-19 Schizophrenia; LIHC cis rs950169 0.580 rs17532346 chr15:85171495 A/C cg12863693 chr15:85201151 NMB 0.47 6.84 0.35 3.73e-11 Schizophrenia; LIHC cis rs2120019 1.000 rs67544533 chr15:75361539 A/G cg17294928 chr15:75287854 SCAMP5 -0.56 -8.61 -0.42 2.68e-16 Blood trace element (Zn levels); LIHC cis rs11673344 0.583 rs7254411 chr19:37525871 G/A cg27390819 chr19:37464633 NA -0.44 -5.82 -0.3 1.33e-8 Obesity-related traits; LIHC cis rs9596863 0.898 rs6561746 chr13:54358368 T/C ch.13.53330881F chr13:54432880 NA 0.43 5.82 0.3 1.38e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg14709524 chr16:89940631 TCF25 0.59 7.7 0.38 1.47e-13 Skin colour saturation; LIHC cis rs2455799 0.574 rs2455801 chr3:15701857 C/T cg12698662 chr3:15914712 MIR563 -0.36 -6.57 -0.33 1.93e-10 Mean platelet volume; LIHC cis rs875971 1.000 rs12698523 chr7:65968113 C/G cg11764359 chr7:65958608 NA 0.91 16.9 0.67 5.17e-47 Aortic root size; LIHC cis rs17253792 0.822 rs10149408 chr14:56046075 G/A cg01858014 chr14:56050164 KTN1 -0.74 -8.03 -0.4 1.61e-14 Putamen volume; LIHC cis rs929354 0.713 rs6946660 chr7:156948648 T/C cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs10186029 0.676 rs4673720 chr2:213941581 G/A cg08319019 chr2:214017104 IKZF2 0.41 5.8 0.3 1.49e-8 Systemic sclerosis; LIHC cis rs7044106 0.708 rs10984992 chr9:123473416 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.71 0.38 1.41e-13 Hip circumference adjusted for BMI; LIHC cis rs9733 0.596 rs11803569 chr1:150664077 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.3 0.32 9.39e-10 Tonsillectomy; LIHC cis rs6964587 0.621 rs38798 chr7:92044539 C/A cg17063962 chr7:91808500 NA -0.62 -10.32 -0.49 6.68e-22 Breast cancer; LIHC cis rs4927850 1.000 rs4927850 chr3:195751630 C/T cg01181863 chr3:195395398 SDHAP2 0.54 7.24 0.36 3.06e-12 Pancreatic cancer; LIHC cis rs11758351 1.000 rs11758351 chr6:26203910 T/G cg16070018 chr6:26224392 HIST1H3E 0.55 6.77 0.34 5.69e-11 Gout;Renal underexcretion gout; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01334186 chr1:151372572 PSMB4 0.43 6.68 0.34 9.83e-11 Pancreatic cancer; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg05863534 chr17:34948351 DHRS11 -0.42 -6.4 -0.33 5.07e-10 Alopecia areata; LIHC cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.36 0.45 1.13e-18 Bipolar disorder; LIHC cis rs67311347 1.000 rs7636719 chr3:40432084 C/T cg18306943 chr3:40428807 ENTPD3 0.33 5.72 0.3 2.35e-8 Renal cell carcinoma; LIHC cis rs12594515 1.000 rs8032835 chr15:45997897 C/G cg19682013 chr15:45996608 NA 0.39 6.63 0.34 1.29e-10 Waist circumference;Weight; LIHC cis rs892961 0.932 rs11650011 chr17:75412334 A/G cg01320579 chr17:75405842 SEPT9 0.5 7.16 0.36 5e-12 Airflow obstruction; LIHC cis rs9457247 0.515 rs2757039 chr6:167370353 G/T cg12798992 chr6:167411361 FGFR1OP -0.47 -7.37 -0.37 1.28e-12 Crohn's disease; LIHC cis rs2380220 0.720 rs9400397 chr6:95980623 C/A cg15832292 chr6:96025679 MANEA 0.61 7.72 0.39 1.27e-13 Behavioural disinhibition (generation interaction); LIHC cis rs12950390 0.893 rs12325760 chr17:45840886 C/T cg03474202 chr17:45855739 NA -0.36 -6.13 -0.31 2.48e-9 IgG glycosylation; LIHC cis rs9814567 0.929 rs2241556 chr3:134183312 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 10.5 0.49 1.53e-22 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs62103177 0.561 rs891488 chr18:77637424 T/C cg05926928 chr17:57297772 GDPD1 -0.48 -6.44 -0.33 3.95e-10 Opioid sensitivity; LIHC cis rs12586317 0.514 rs61100068 chr14:35400232 A/T cg05294307 chr14:35346193 BAZ1A -0.54 -7.78 -0.39 8.89e-14 Psoriasis; LIHC cis rs2066819 1.000 rs41392645 chr12:56696742 A/G cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs11711311 0.910 rs62265549 chr3:113396234 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.4 6.79 0.34 4.83e-11 IgG glycosylation; LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs826838 0.616 rs4418873 chr12:38625473 C/A cg26384229 chr12:38710491 ALG10B 0.43 6.49 0.33 2.93e-10 Heart rate; LIHC cis rs68170813 0.559 rs10487271 chr7:106898458 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs1577917 0.958 rs10944144 chr6:86537755 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.21 -0.52 4.62e-25 Response to antipsychotic treatment; LIHC cis rs1355223 0.902 rs286858 chr11:34717357 T/C cg11058730 chr11:34937778 PDHX;APIP 0.45 6.29 0.32 9.77e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg16405210 chr4:1374714 KIAA1530 -0.89 -14.58 -0.62 8.39e-38 Longevity; LIHC cis rs2760061 0.626 rs634106 chr1:228121548 C/T cg01200585 chr1:228362443 C1orf69 -0.39 -5.83 -0.3 1.3e-8 Diastolic blood pressure; LIHC cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg12311346 chr5:56204834 C5orf35 -0.57 -7.46 -0.37 7.05e-13 Initial pursuit acceleration; LIHC cis rs36051895 0.732 rs7046736 chr9:5015732 C/A cg02405213 chr9:5042618 JAK2 -0.64 -11.12 -0.52 9.66e-25 Pediatric autoimmune diseases; LIHC cis rs7224737 1.000 rs7224737 chr17:40289364 A/G cg02228675 chr17:40259724 DHX58 0.24 5.71 0.3 2.4e-8 Fibrinogen levels; LIHC cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg13393036 chr8:95962371 TP53INP1 -0.41 -9.29 -0.45 1.8e-18 Type 2 diabetes; LIHC cis rs7953508 0.506 rs3869308 chr12:93959918 A/G cg18151635 chr12:93972918 NA -0.51 -8.49 -0.42 6.52e-16 Pubertal anthropometrics; LIHC cis rs7552404 1.000 rs7534754 chr1:76185308 G/A cg03433033 chr1:76189801 ACADM 0.66 9.15 0.44 5.17e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7772486 0.806 rs4243478 chr6:146284560 A/G cg05347473 chr6:146136440 FBXO30 -0.35 -5.88 -0.3 9.73e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg00149659 chr3:10157352 C3orf10 0.68 7.2 0.36 3.97e-12 Alzheimer's disease; LIHC cis rs74233809 1.000 rs10883808 chr10:104721126 A/T cg03493300 chr10:104813866 CNNM2 0.45 5.95 0.31 6.73e-9 Birth weight; LIHC cis rs6933660 0.745 rs6557138 chr6:151732017 C/T cg02564969 chr6:151773285 C6orf211;RMND1 0.4 5.73 0.3 2.24e-8 Menarche (age at onset); LIHC cis rs15676 0.947 rs7854319 chr9:131567995 G/A cg00228799 chr9:131580591 ENDOG -0.45 -6.78 -0.34 5.33e-11 Blood metabolite levels; LIHC cis rs12477438 0.765 rs2278895 chr2:99613484 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.65 -0.38 2.08e-13 Chronic sinus infection; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11339840 chr1:203596058 ATP2B4 0.39 6.29 0.32 9.69e-10 Cognitive function; LIHC cis rs1790761 0.667 rs591434 chr11:67337814 C/T cg21734168 chr11:67353974 GSTP1 -0.28 -6.79 -0.34 4.99e-11 Mean corpuscular volume; LIHC cis rs75908454 1.000 rs2865094 chr6:169919616 G/A cg19338460 chr6:170058176 WDR27 -0.83 -7.45 -0.37 7.84e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC trans rs2727020 0.521 rs7930855 chr11:49521660 C/T cg03929089 chr4:120376271 NA 0.7 10.21 0.48 1.57e-21 Coronary artery disease; LIHC cis rs75908454 1.000 rs78797236 chr6:169820344 G/A cg19338460 chr6:170058176 WDR27 -0.86 -7.47 -0.37 6.6e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs870825 0.655 rs2017101 chr4:185637381 G/A cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC trans rs1005277 0.579 rs2504148 chr10:38400788 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs7264396 0.733 rs6060515 chr20:34211779 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -9.77 -0.47 4.92e-20 Total cholesterol levels; LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg14257396 chr1:107603778 NA -0.38 -6.34 -0.32 7.32e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs876084 0.505 rs4407921 chr8:121156585 C/T cg06265175 chr8:121136014 COL14A1 0.43 6.88 0.35 2.9e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1728785 0.892 rs1103955 chr16:68588488 T/G cg02972257 chr16:68554789 NA -0.53 -5.93 -0.31 7.57e-9 Ulcerative colitis; LIHC cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg06634786 chr22:41940651 POLR3H -0.82 -8.76 -0.43 9.32e-17 Vitiligo; LIHC cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg18357526 chr6:26021779 HIST1H4A -0.54 -6.49 -0.33 2.97e-10 Blood metabolite levels; LIHC trans rs1814175 0.645 rs7928714 chr11:49887622 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.95 0.35 1.82e-11 Height; LIHC cis rs904251 0.523 rs2797798 chr6:37481437 C/T cg01843034 chr6:37503916 NA -0.48 -8.24 -0.41 3.59e-15 Cognitive performance; LIHC trans rs3780486 0.846 rs7864705 chr9:33140352 A/C cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs332507 0.830 rs13097438 chr3:124429848 T/C cg05980111 chr3:124395277 KALRN 0.41 6.19 0.32 1.71e-9 Plateletcrit; LIHC cis rs801193 0.935 rs3800820 chr7:66147178 C/T cg00343986 chr7:65444356 GUSB -0.4 -5.98 -0.31 5.75e-9 Aortic root size; LIHC trans rs7091068 0.518 rs1572772 chr10:95432862 A/G cg03941975 chr13:19919758 LOC100101938 -0.24 -6.08 -0.31 3.3e-9 Urinary tract infection frequency; LIHC cis rs2067615 0.507 rs1922432 chr12:107077232 G/A cg15890332 chr12:107067104 RFX4 0.27 6.35 0.32 6.99e-10 Heart rate; LIHC cis rs17270561 0.779 rs78589800 chr6:25883500 C/G cg17691542 chr6:26056736 HIST1H1C 0.82 9.64 0.46 1.29e-19 Iron status biomarkers; LIHC cis rs10744422 1.000 rs921808 chr12:123323135 A/G cg22842854 chr12:123319900 HIP1R 0.65 8.57 0.42 3.5e-16 Schizophrenia; LIHC cis rs1008375 0.897 rs4334752 chr4:17615430 C/T cg02297831 chr4:17616191 MED28 0.49 7.4 0.37 1.07e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs317689 0.690 rs7969559 chr12:69655167 A/G cg19645103 chr12:69753606 YEATS4 -0.44 -5.96 -0.31 6.44e-9 Response to diuretic therapy; LIHC cis rs6461049 0.734 rs1558465 chr7:2151398 G/C cg20295408 chr7:1910781 MAD1L1 -0.43 -6.28 -0.32 1.01e-9 Schizophrenia; LIHC cis rs12586317 0.525 rs10144430 chr14:35433682 T/A cg16230307 chr14:35515116 FAM177A1 0.65 10.92 0.51 5.18e-24 Psoriasis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01836096 chr8:145578603 C8ORFK29 0.42 6.15 0.32 2.11e-9 Longevity; LIHC cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg03452623 chr4:187889614 NA -0.32 -8.31 -0.41 2.33e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs700651 0.753 rs10207232 chr2:198893813 A/G cg00792783 chr2:198669748 PLCL1 0.45 6.5 0.33 2.9e-10 Intracranial aneurysm; LIHC cis rs1538970 0.924 rs1006216 chr1:45909994 A/G cg15605315 chr1:45957053 TESK2 -0.44 -5.76 -0.3 1.84e-8 Platelet count; LIHC trans rs6489882 0.902 rs7966314 chr12:113372539 C/T cg10175203 chr3:128143634 NA -0.38 -6.19 -0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC cis rs597539 0.652 rs686877 chr11:68637169 G/A cg04772025 chr11:68637568 NA 0.46 6.22 0.32 1.44e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.53 -7.52 -0.38 4.84e-13 Lymphocyte counts; LIHC cis rs4555082 0.874 rs2816625 chr14:105734565 G/A cg13114125 chr14:105738426 BRF1 -0.74 -9.66 -0.46 1.07e-19 Mean platelet volume;Platelet distribution width; LIHC trans rs1814175 0.527 rs10769595 chr11:49638212 A/G cg15704280 chr7:45808275 SEPT13 -0.77 -11.48 -0.53 4.99e-26 Height; LIHC cis rs2066819 0.892 rs117305040 chr12:56657888 A/G cg26734620 chr12:56694298 CS 1.28 10.93 0.51 4.77e-24 Psoriasis vulgaris; LIHC cis rs4423214 0.879 rs736894 chr11:71152258 A/G cg05163923 chr11:71159392 DHCR7 0.63 8.63 0.42 2.38e-16 Vitamin D levels; LIHC cis rs243505 0.660 rs243487 chr7:148448211 G/A cg09806900 chr7:148480153 CUL1 -0.43 -6.01 -0.31 4.89e-9 Inflammatory bowel disease;Crohn's disease; LIHC trans rs3960554 0.808 rs4728587 chr7:75803132 C/T cg19862616 chr7:65841803 NCRNA00174 0.61 8.3 0.41 2.45e-15 Eotaxin levels; LIHC cis rs7312933 1.000 rs7957213 chr12:42475438 T/G cg17420585 chr12:42539391 GXYLT1 -0.37 -5.89 -0.3 9.43e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs13108904 0.518 rs4974602 chr4:1342391 C/T cg13395646 chr4:1353034 KIAA1530 -0.85 -12.92 -0.57 2.19e-31 Obesity-related traits; LIHC cis rs2976388 1.000 rs2294010 chr8:143762430 A/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs1506636 0.646 rs805779 chr7:123214835 C/T cg03229431 chr7:123269106 ASB15 -0.45 -9.04 -0.44 1.21e-17 Plateletcrit;Platelet count; LIHC cis rs896854 0.552 rs2515236 chr8:95934907 A/G cg16049864 chr8:95962084 TP53INP1 0.52 8.17 0.4 6.09e-15 Type 2 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12887701 chr11:96123196 JRKL;CCDC82 0.45 6.33 0.32 7.66e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg11644478 chr21:40555479 PSMG1 0.44 6.96 0.35 1.79e-11 Cognitive function; LIHC cis rs919433 0.679 rs6719832 chr2:198533369 C/T cg10820045 chr2:198174542 NA -0.46 -7.25 -0.36 2.85e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs904251 0.600 rs9380673 chr6:37415125 T/C cg01843034 chr6:37503916 NA -0.37 -6.07 -0.31 3.49e-9 Cognitive performance; LIHC cis rs7223966 0.881 rs3020608 chr17:61979993 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.17 0.32 1.96e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs34779708 0.966 rs35079558 chr10:35479886 A/G cg04310649 chr10:35416472 CREM -0.42 -5.71 -0.3 2.45e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg00091569 chr3:40428383 ENTPD3 0.38 6.51 0.33 2.63e-10 Renal cell carcinoma; LIHC cis rs2072499 0.966 rs2842865 chr1:156159532 G/A cg24450063 chr1:156163899 SLC25A44 1.07 18.56 0.71 1.07e-53 Testicular germ cell tumor; LIHC cis rs7945705 0.902 rs2016942 chr11:8938787 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.4 6.7 0.34 8.75e-11 Hemoglobin concentration; LIHC cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.89e-30 Menopause (age at onset); LIHC cis rs4788570 0.584 rs4788548 chr16:71655361 A/G cg06353428 chr16:71660113 MARVELD3 1.01 10.93 0.51 4.65e-24 Intelligence (multi-trait analysis); LIHC cis rs904251 0.523 rs914348 chr6:37484729 G/A cg01843034 chr6:37503916 NA -0.47 -7.94 -0.39 2.86e-14 Cognitive performance; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07120806 chr4:1873451 WHSC1 0.45 6.17 0.32 1.91e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1580019 0.537 rs7804609 chr7:32558094 A/C cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.76 0.43 9.26e-17 Cognitive ability; LIHC cis rs9733 0.596 rs6587518 chr1:150661787 T/C cg17724175 chr1:150552817 MCL1 0.48 9.72 0.47 7.13e-20 Tonsillectomy; LIHC cis rs11676348 0.755 rs13410318 chr2:219022910 T/G cg20019365 chr2:219134978 PNKD;AAMP 0.55 7.44 0.37 8.16e-13 Ulcerative colitis; LIHC cis rs2153535 0.541 rs6932434 chr6:8467679 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs7512552 0.839 rs1260405 chr1:150304781 A/G cg15654264 chr1:150340011 RPRD2 0.69 11.33 0.52 1.78e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9888615 0.646 rs3825593 chr14:53386237 C/G cg00686598 chr14:53173677 PSMC6 -0.46 -6.12 -0.31 2.51e-9 Systolic blood pressure; LIHC cis rs17095355 1.000 rs12267704 chr10:111722008 C/T cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.84 -0.3 1.21e-8 Biliary atresia; LIHC cis rs9399135 0.935 rs6908681 chr6:135337733 A/G cg22676075 chr6:135203613 NA 0.4 6.51 0.33 2.73e-10 Red blood cell count; LIHC cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.82 0.51 1.15e-23 Colorectal cancer; LIHC cis rs965469 0.857 rs6037523 chr20:3249463 A/T cg25506879 chr20:3388711 C20orf194 -0.56 -6.86 -0.35 3.2e-11 IFN-related cytopenia; LIHC trans rs7618501 1.000 rs11709680 chr3:49745188 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC trans rs875971 1.000 rs1544549 chr7:66090663 T/A cg10756647 chr7:56101905 PSPH -0.47 -7.03 -0.36 1.14e-11 Aortic root size; LIHC cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg27297192 chr10:134578999 INPP5A -0.46 -6.42 -0.33 4.65e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1538970 0.961 rs4660854 chr1:45854087 A/T cg24296786 chr1:45957014 TESK2 -0.51 -7.72 -0.39 1.32e-13 Platelet count; LIHC cis rs62380364 0.626 rs11749912 chr5:88065628 A/G cg22951263 chr5:87985283 NA -0.42 -7.05 -0.36 9.96e-12 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18128437 chr3:167453397 PDCD10;SERPINI1 0.47 6.38 0.33 5.84e-10 Lung function (FEV1/FVC); LIHC cis rs2795502 0.873 rs2077626 chr10:43410962 A/G cg20628663 chr10:43360327 NA 0.45 6.7 0.34 8.53e-11 Blood protein levels; LIHC cis rs1797081 1.000 rs780634 chr10:16864327 T/G cg23933602 chr10:16859644 RSU1 1.02 20.1 0.74 7.18e-60 Platelet distribution width; LIHC cis rs10751667 0.666 rs7395182 chr11:927553 A/C ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg13271783 chr10:134563150 INPP5A -0.61 -7.26 -0.37 2.56e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1005277 0.579 rs2474584 chr10:38416389 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.38 -0.56 2.36e-29 Extrinsic epigenetic age acceleration; LIHC cis rs1865721 1.000 rs62089511 chr18:73197629 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.16e-13 Intelligence; LIHC cis rs6952809 0.504 rs1978169 chr7:2434522 G/A cg23289794 chr7:2394357 EIF3B -0.6 -6.19 -0.32 1.77e-9 Multiple sclerosis; LIHC cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.71 0.38 1.43e-13 Bipolar disorder; LIHC cis rs3768617 0.510 rs12086466 chr1:183075778 C/T ch.1.3577855R chr1:183094577 LAMC1 -0.61 -10.56 -0.5 9.69e-23 Fuchs's corneal dystrophy; LIHC cis rs9394841 0.667 rs9471653 chr6:41755410 C/G cg08135965 chr6:41755394 TOMM6 0.44 5.72 0.3 2.34e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs17685 0.753 rs11972240 chr7:75694079 A/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs61931739 0.500 rs7979482 chr12:34542877 C/A cg26384229 chr12:38710491 ALG10B 0.77 9.2 0.45 3.66e-18 Morning vs. evening chronotype; LIHC cis rs9611565 0.506 rs2024567 chr22:41699206 G/C cg06634786 chr22:41940651 POLR3H -0.53 -6.26 -0.32 1.17e-9 Vitiligo; LIHC cis rs9918079 0.560 rs10008975 chr4:15624571 C/T cg21123203 chr4:15471301 CC2D2A -0.45 -7.23 -0.36 3.12e-12 Obesity-related traits; LIHC cis rs1003719 0.680 rs3992 chr21:38505969 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.46e-25 Eye color traits; LIHC cis rs3809566 1.000 rs4775610 chr15:63332057 C/T cg05771511 chr15:63340396 TPM1 -0.47 -6.96 -0.35 1.73e-11 Platelet count; LIHC cis rs8062405 0.690 rs762634 chr16:28603335 T/C cg07382826 chr16:28625726 SULT1A1 0.52 7.84 0.39 5.68e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6430585 0.528 rs16832205 chr2:136684632 G/A cg07169764 chr2:136633963 MCM6 1.29 21.48 0.76 2.15e-65 Corneal structure; LIHC cis rs1403694 0.515 rs1656925 chr3:186449123 T/C cg12454167 chr3:186435060 KNG1 0.3 7.05 0.36 1.01e-11 Blood protein levels; LIHC cis rs6582630 0.555 rs1906260 chr12:38601013 T/G cg13010199 chr12:38710504 ALG10B 0.59 6.99 0.35 1.44e-11 Drug-induced liver injury (flucloxacillin); LIHC trans rs7618501 0.603 rs72942333 chr3:49986118 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.57 9.36 0.45 1.1e-18 Intelligence (multi-trait analysis); LIHC cis rs6964587 0.692 rs2158138 chr7:91700879 A/G cg17063962 chr7:91808500 NA 0.66 11.86 0.54 2.12e-27 Breast cancer; LIHC cis rs7772486 0.686 rs1415744 chr6:146022531 C/T cg05347473 chr6:146136440 FBXO30 0.36 5.95 0.31 6.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs769267 0.895 rs2315279 chr19:19479936 C/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.01 -0.31 4.78e-9 Tonsillectomy; LIHC cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg09060608 chr5:178986726 RUFY1 -0.41 -6.26 -0.32 1.16e-9 Lung cancer; LIHC trans rs1005277 0.603 rs1998062 chr10:38457652 G/C cg17830980 chr10:43048298 ZNF37B -0.56 -11.21 -0.52 4.69e-25 Extrinsic epigenetic age acceleration; LIHC cis rs11628318 0.614 rs10132160 chr14:103058023 A/G cg23461800 chr14:103021989 NA -0.45 -6.12 -0.31 2.63e-9 Platelet count; LIHC cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.3 -0.32 9.26e-10 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03562264 chr6:36646551 CDKN1A 0.54 6.76 0.34 5.89e-11 Lung function (FEV1/FVC); LIHC cis rs6466055 0.637 rs1144 chr7:104756355 T/C cg04380332 chr7:105027541 SRPK2 -0.33 -6.29 -0.32 9.69e-10 Schizophrenia; LIHC cis rs9790314 0.612 rs9875200 chr3:160733708 A/G cg03342759 chr3:160939853 NMD3 -0.58 -8.0 -0.4 1.94e-14 Morning vs. evening chronotype; LIHC cis rs7258465 1.000 rs4808136 chr19:18618867 A/G cg10790698 chr19:18539756 SSBP4 0.32 6.8 0.34 4.78e-11 Breast cancer; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg11494091 chr17:61959527 GH2 0.44 7.91 0.39 3.7e-14 Prudent dietary pattern; LIHC cis rs722599 0.562 rs2287400 chr14:75182937 G/A cg08847533 chr14:75593920 NEK9 0.48 7.42 0.37 9.52e-13 IgG glycosylation; LIHC cis rs7927771 0.896 rs12794570 chr11:47658314 C/T cg18512352 chr11:47633146 NA -0.25 -5.89 -0.3 9.48e-9 Subjective well-being; LIHC cis rs9858542 0.537 rs9874474 chr3:49326178 A/G cg07636037 chr3:49044803 WDR6 -0.53 -5.87 -0.3 1.03e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4561483 0.798 rs456325 chr16:12012562 C/G cg08843971 chr16:11963173 GSPT1 -0.35 -7.08 -0.36 8.15e-12 Testicular germ cell tumor; LIHC cis rs1862618 0.671 rs2255726 chr5:56243128 T/C cg24531977 chr5:56204891 C5orf35 0.52 7.63 0.38 2.37e-13 Initial pursuit acceleration; LIHC cis rs7107174 1.000 rs9651769 chr11:77996166 T/C cg02023728 chr11:77925099 USP35 0.5 9.63 0.46 1.4e-19 Testicular germ cell tumor; LIHC cis rs9640161 0.750 rs3735173 chr7:150020526 C/T cg10018233 chr7:150070692 REPIN1 0.55 9.49 0.46 3.99e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs9527 0.830 rs12249194 chr10:104643698 T/C cg15744005 chr10:104629667 AS3MT -0.34 -6.73 -0.34 7.2e-11 Arsenic metabolism; LIHC cis rs9902453 0.740 rs2628189 chr17:28088813 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -13.49 -0.59 1.51e-33 Coffee consumption (cups per day); LIHC cis rs56104184 0.723 rs73063524 chr19:49409004 T/C cg15549821 chr19:49342101 PLEKHA4 -0.65 -6.17 -0.32 1.9e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7945718 0.650 rs10831889 chr11:12665834 A/T cg25843174 chr11:12811716 TEAD1 0.34 7.69 0.38 1.55e-13 Educational attainment (years of education); LIHC cis rs7582720 1.000 rs75869289 chr2:203806724 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1801251 1.000 rs2675974 chr2:233727071 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.25 0.52 3.45e-25 Coronary artery disease; LIHC cis rs6831352 0.819 rs1230155 chr4:99989259 C/T cg12011299 chr4:100065546 ADH4 0.51 8.81 0.43 6.36e-17 Alcohol dependence; LIHC cis rs6594499 0.872 rs6880351 chr5:110451664 C/G cg04022379 chr5:110408740 TSLP 0.49 8.2 0.41 4.92e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7945718 0.967 rs11022491 chr11:12777620 A/G cg25843174 chr11:12811716 TEAD1 -0.34 -7.94 -0.39 2.88e-14 Educational attainment (years of education); LIHC trans rs116095464 0.867 rs7726582 chr5:215349 C/G cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg11890956 chr21:40555474 PSMG1 -0.48 -7.95 -0.4 2.67e-14 Cognitive function; LIHC cis rs11711311 1.000 rs9811200 chr3:113531180 A/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.47 8.77 0.43 8.72e-17 IgG glycosylation; LIHC cis rs7089973 0.604 rs11196924 chr10:116571796 A/C cg23260525 chr10:116636907 FAM160B1 -0.33 -6.11 -0.31 2.75e-9 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs16828019 0.852 rs71648535 chr1:41613750 G/A cg03387723 chr1:41708464 SCMH1 -0.45 -7.22 -0.36 3.37e-12 Intelligence (multi-trait analysis); LIHC cis rs9486719 1.000 rs12207570 chr6:96987884 A/C cg06623918 chr6:96969491 KIAA0776 -0.76 -7.48 -0.38 6.14e-13 Migraine;Coronary artery disease; LIHC trans rs6952808 0.595 rs3800916 chr7:2166072 C/T cg04565464 chr8:145669602 NFKBIL2 0.38 6.37 0.33 5.97e-10 Bipolar disorder and schizophrenia; LIHC cis rs3617 0.625 rs7612624 chr3:52893426 T/C cg11645453 chr3:52864694 ITIH4 -0.23 -6.13 -0.31 2.41e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs5769765 1.000 rs5769765 chr22:50271176 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs2153535 0.580 rs9379213 chr6:8474945 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg01368799 chr11:117014884 PAFAH1B2 0.42 5.87 0.3 1.04e-8 Blood protein levels; LIHC cis rs6933660 0.720 rs6914656 chr6:151753421 C/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.53 -8.1 -0.4 9.94e-15 Menarche (age at onset); LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg24209194 chr3:40518798 ZNF619 -0.58 -8.94 -0.44 2.42e-17 Renal cell carcinoma; LIHC cis rs7897654 0.571 rs12765002 chr10:104635348 C/T cg15744005 chr10:104629667 AS3MT -0.37 -7.53 -0.38 4.5e-13 Schizophrenia; LIHC cis rs3008870 1.000 rs2985825 chr1:67412822 T/G cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg13409248 chr3:40428643 ENTPD3 0.49 8.3 0.41 2.48e-15 Renal cell carcinoma; LIHC cis rs34172651 0.917 rs2343606 chr16:24793741 C/T cg04756594 chr16:24857601 SLC5A11 0.47 7.32 0.37 1.8e-12 Intelligence (multi-trait analysis); LIHC cis rs56235845 0.685 rs35630910 chr5:176757841 A/C cg06060754 chr5:176797920 RGS14 0.61 7.74 0.39 1.16e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs6486730 0.508 rs7133440 chr12:129269244 A/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.35 5.89 0.3 9.24e-9 Systemic lupus erythematosus; LIHC cis rs11583043 0.958 rs12730160 chr1:101438791 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.94 0.44 2.5e-17 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs11112613 0.938 rs2374513 chr12:106007300 C/T cg03607813 chr12:105948248 NA 0.52 8.5 0.42 5.78e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25671651 chr2:203776787 ALS2CR8;WDR12 0.43 6.64 0.34 1.22e-10 Cognitive function; LIHC trans rs3780486 1.000 rs12342831 chr9:33124872 A/G cg20290983 chr6:43655470 MRPS18A 1.07 20.73 0.75 2.12e-62 IgG glycosylation; LIHC cis rs11628318 0.614 rs942022 chr14:103108842 C/T cg01864069 chr14:103024347 NA -0.46 -7.26 -0.37 2.66e-12 Platelet count; LIHC cis rs2180341 0.961 rs910720 chr6:127619070 T/C cg24812749 chr6:127587940 RNF146 1.07 16.08 0.66 9.77e-44 Breast cancer; LIHC cis rs11630290 0.592 rs1039817 chr15:64155367 T/A cg12036633 chr15:63758958 NA 0.63 6.75 0.34 6.36e-11 Iris characteristics; LIHC cis rs17685 0.753 rs2302435 chr7:75676987 G/A cg16684958 chr7:75615977 POR -0.5 -8.27 -0.41 2.91e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9549367 0.713 rs4907598 chr13:113861385 C/T cg18105134 chr13:113819100 PROZ 0.63 11.08 0.51 1.34e-24 Platelet distribution width; LIHC trans rs459571 0.959 rs2520100 chr9:136918137 A/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.56 -8.58 -0.42 3.32e-16 Platelet distribution width; LIHC cis rs274567 0.550 rs272885 chr5:131667736 A/G cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.82e-31 Blood metabolite levels; LIHC cis rs6882046 0.513 rs681446 chr5:88054292 C/T cg22951263 chr5:87985283 NA 0.4 7.09 0.36 7.67e-12 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs7615952 0.515 rs4267608 chr3:125680500 C/T cg05084668 chr3:125655381 ALG1L -0.53 -8.3 -0.41 2.51e-15 Blood pressure (smoking interaction); LIHC cis rs9811920 0.609 rs6440938 chr3:99652092 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.89 0.35 2.64e-11 Axial length; LIHC cis rs6952809 0.532 rs6461361 chr7:2432167 A/G cg23289794 chr7:2394357 EIF3B -0.69 -6.72 -0.34 7.78e-11 Multiple sclerosis; LIHC cis rs2236918 1.000 rs1635509 chr1:242028027 C/T cg17736920 chr1:242011382 EXO1 0.6 9.04 0.44 1.22e-17 Menopause (age at onset); LIHC cis rs7617773 0.780 rs2541 chr3:48339618 A/G cg11946769 chr3:48343235 NME6 0.92 11.62 0.53 1.58e-26 Coronary artery disease; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg04234412 chr22:24373322 LOC391322 -0.72 -11.13 -0.52 8.93e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4478037 0.822 rs3924695 chr3:33122085 C/T cg16652328 chr3:33138982 GLB1;TMPPE -0.52 -6.79 -0.34 4.93e-11 Major depressive disorder; LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg11060661 chr22:24314208 DDT;DDTL 0.61 10.43 0.49 2.79e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17125944 0.505 rs76219229 chr14:53178346 G/A cg00686598 chr14:53173677 PSMC6 1.22 15.86 0.65 7.79e-43 Alzheimer's disease (late onset); LIHC cis rs651907 0.557 rs34457525 chr3:101435225 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.61 0.5 6.33e-23 Colorectal cancer; LIHC cis rs10792665 0.606 rs7131210 chr11:82609340 A/T cg24227371 chr11:82718527 RAB30 -0.27 -6.39 -0.33 5.53e-10 Obesity-related traits; LIHC cis rs763121 0.853 rs2235230 chr22:39124467 A/G cg14440974 chr22:39074834 NA 0.44 7.04 0.36 1.07e-11 Menopause (age at onset); LIHC cis rs10876993 0.855 rs1689601 chr12:58049557 G/A cg15848620 chr12:58087721 OS9 -0.55 -7.43 -0.37 8.96e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs1878931 0.582 rs9937267 chr16:3421073 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.68 9.0 0.44 1.63e-17 Body mass index (adult); LIHC cis rs11112613 0.595 rs871219 chr12:105938519 C/A cg03607813 chr12:105948248 NA 0.62 11.56 0.53 2.66e-26 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs2153535 0.601 rs2327059 chr6:8447071 A/G cg23788917 chr6:8435910 SLC35B3 0.62 8.84 0.43 5.15e-17 Motion sickness; LIHC cis rs4919694 0.536 rs12414777 chr10:104697781 C/T cg04362960 chr10:104952993 NT5C2 0.48 6.52 0.33 2.49e-10 Arsenic metabolism; LIHC cis rs2439831 0.850 rs558656 chr15:43723514 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.73 0.43 1.12e-16 Lung cancer in ever smokers; LIHC cis rs1801251 0.963 rs66549961 chr2:233602293 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.05 0.51 1.82e-24 Coronary artery disease; LIHC cis rs8180040 0.676 rs11130114 chr3:47154651 T/G cg16586182 chr3:47516702 SCAP -0.51 -9.46 -0.46 5.27e-19 Colorectal cancer; LIHC cis rs9733 0.596 rs12072339 chr1:150686099 A/G cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs10857712 0.851 rs56153177 chr10:135216975 G/A cg01444801 chr10:135216882 MTG1 -0.65 -9.78 -0.47 4.59e-20 Systemic lupus erythematosus; LIHC cis rs10489202 0.608 rs10800334 chr1:168075613 T/C cg24449463 chr1:168025552 DCAF6 -0.46 -6.42 -0.33 4.46e-10 Schizophrenia; LIHC cis rs473651 0.935 rs474478 chr2:239335473 C/T cg21699342 chr2:239360505 ASB1 0.34 6.6 0.34 1.56e-10 Multiple system atrophy; LIHC cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg27170947 chr2:26402098 FAM59B 0.67 8.4 0.41 1.19e-15 Gut microbiome composition (summer); LIHC cis rs1005277 0.529 rs1780125 chr10:38531376 A/G cg17219203 chr10:38645113 HSD17B7P2 -0.39 -5.72 -0.3 2.34e-8 Extrinsic epigenetic age acceleration; LIHC cis rs12586317 0.553 rs78124218 chr14:35570606 G/A cg05294307 chr14:35346193 BAZ1A -0.46 -6.71 -0.34 7.98e-11 Psoriasis; LIHC cis rs6547741 0.935 rs4666004 chr2:27855052 T/A cg27432699 chr2:27873401 GPN1 0.77 12.85 0.57 4.21e-31 Oral cavity cancer; LIHC cis rs7945718 0.621 rs10831890 chr11:12671211 A/G cg25843174 chr11:12811716 TEAD1 0.33 7.64 0.38 2.21e-13 Educational attainment (years of education); LIHC cis rs75908454 1.000 rs75490272 chr6:169900464 C/T cg19338460 chr6:170058176 WDR27 -0.75 -6.8 -0.35 4.69e-11 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs7592578 0.723 rs4371384 chr2:191430741 A/G cg10560079 chr2:191398806 TMEM194B 0.88 12.74 0.57 1.06e-30 Diastolic blood pressure; LIHC cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg27170947 chr2:26402098 FAM59B -0.71 -8.73 -0.43 1.13e-16 Gut microbiome composition (summer); LIHC cis rs2845885 0.744 rs2701540 chr11:63869107 T/A cg05555928 chr11:63887634 MACROD1 0.48 6.26 0.32 1.17e-9 Body mass index; LIHC cis rs801193 0.660 rs10950049 chr7:66230860 T/C cg18876405 chr7:65276391 NA 0.33 6.05 0.31 3.83e-9 Aortic root size; LIHC cis rs74233809 1.000 rs10883832 chr10:104871279 T/G cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.43e-9 Birth weight; LIHC cis rs2455799 0.573 rs2470546 chr3:15733897 T/C cg12698662 chr3:15914712 MIR563 -0.35 -6.53 -0.33 2.33e-10 Mean platelet volume; LIHC trans rs259842 0.800 rs6725456 chr2:180718419 C/T cg00945735 chr7:41982767 NA 0.39 6.05 0.31 3.89e-9 Blood protein levels; LIHC trans rs916888 0.821 rs199504 chr17:44861003 C/T cg26692224 chr17:62915920 LRRC37A3 0.68 6.44 0.33 4.06e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs7937682 0.558 rs7113067 chr11:111692182 G/A cg09085632 chr11:111637200 PPP2R1B 0.94 13.94 0.6 2.65e-35 Primary sclerosing cholangitis; LIHC cis rs2576037 0.583 rs10070 chr18:44388899 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 10.78 0.5 1.65e-23 Personality dimensions; LIHC cis rs7523273 0.565 rs11118453 chr1:207887996 A/C cg22525895 chr1:207977042 MIR29B2 0.53 7.91 0.39 3.54e-14 Schizophrenia; LIHC cis rs4268898 0.722 rs10445893 chr2:24407128 A/G cg06627628 chr2:24431161 ITSN2 0.44 6.27 0.32 1.06e-9 Asthma; LIHC cis rs8180040 0.726 rs1869869 chr3:47027833 G/A cg16586182 chr3:47516702 SCAP -0.46 -8.05 -0.4 1.39e-14 Colorectal cancer; LIHC trans rs75804782 0.521 rs72994973 chr2:239428315 C/T cg01134436 chr17:81009848 B3GNTL1 0.74 6.39 0.33 5.39e-10 Morning vs. evening chronotype;Chronotype; LIHC trans rs1814175 0.645 rs10839448 chr11:49938930 G/A cg03929089 chr4:120376271 NA -0.84 -15.86 -0.65 7.39e-43 Height; LIHC cis rs796364 1.000 rs11680723 chr2:200810957 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.69 -6.65 -0.34 1.17e-10 Schizophrenia; LIHC cis rs1030268 1.000 rs1030268 chr7:133606631 C/T cg03336402 chr7:133662267 EXOC4 0.5 6.85 0.35 3.44e-11 Intelligence (multi-trait analysis); LIHC cis rs8058578 0.832 rs7500719 chr16:30840877 C/T cg00531865 chr16:30841666 NA -0.41 -6.23 -0.32 1.37e-9 Multiple myeloma; LIHC cis rs9902453 0.904 rs12103671 chr17:28408217 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.64 -0.59 4.14e-34 Coffee consumption (cups per day); LIHC cis rs1728785 0.748 rs889560 chr16:68605784 A/G cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs1003719 0.614 rs1053808 chr21:38525356 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.87 -0.51 7.86e-24 Eye color traits; LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg02209998 chr8:649235 ERICH1 0.62 6.28 0.32 1e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs9457247 1.000 rs413232 chr6:167400972 G/A cg07741184 chr6:167504864 NA 0.25 5.84 0.3 1.24e-8 Crohn's disease; LIHC cis rs546131 0.963 rs539044 chr11:34841542 G/T cg11058730 chr11:34937778 PDHX;APIP 0.62 9.47 0.46 4.67e-19 Lung disease severity in cystic fibrosis; LIHC cis rs17539620 0.519 rs871071 chr6:154837667 T/C cg20019720 chr6:154832845 CNKSR3 0.45 7.17 0.36 4.62e-12 Lipoprotein (a) levels; LIHC trans rs2727020 0.729 rs34647977 chr11:49195543 G/A cg18944383 chr4:111397179 ENPEP 0.25 6.08 0.31 3.24e-9 Coronary artery disease; LIHC cis rs8017423 0.967 rs4900033 chr14:90701963 C/A cg14092571 chr14:90743983 NA -0.38 -5.96 -0.31 6.43e-9 Mortality in heart failure; LIHC cis rs7123876 0.830 rs57614870 chr11:72435983 A/G cg03713592 chr11:72463424 ARAP1 0.57 6.48 0.33 3.26e-10 Body mass index; LIHC cis rs9911578 0.967 rs6416932 chr17:57148991 G/A cg12560992 chr17:57184187 TRIM37 0.97 17.95 0.7 3.2e-51 Intelligence (multi-trait analysis); LIHC cis rs12971120 0.891 rs11151961 chr18:72177340 C/T cg25817165 chr18:72167213 CNDP2 -0.71 -12.24 -0.55 8.01e-29 Refractive error; LIHC trans rs2797160 0.904 rs1418637 chr6:125992553 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.49 -6.76 -0.34 5.93e-11 Endometrial cancer; LIHC cis rs898097 0.690 rs12452304 chr17:80811659 G/A cg15369054 chr17:80825471 TBCD 0.42 6.05 0.31 3.82e-9 Breast cancer; LIHC trans rs10117734 0.632 rs10974525 chr9:4417406 A/G cg00829944 chr11:64052608 BAD;GPR137 -0.46 -6.44 -0.33 4.1e-10 Parental extreme longevity (95 years and older); LIHC cis rs904251 0.523 rs12202055 chr6:37486080 A/T cg08126542 chr6:37504118 NA -0.36 -5.92 -0.3 7.8e-9 Cognitive performance; LIHC cis rs6500602 0.702 rs11076834 chr16:4549583 C/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.35 0.32 6.89e-10 Schizophrenia; LIHC cis rs12594515 1.000 rs8027000 chr15:45987795 T/C cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.69e-19 Waist circumference;Weight; LIHC cis rs4780401 0.609 rs9924522 chr16:11816852 C/A cg01061890 chr16:11836724 TXNDC11 -0.65 -10.47 -0.49 1.92e-22 Rheumatoid arthritis; LIHC cis rs919433 0.963 rs4850786 chr2:198178608 A/G cg03934865 chr2:198174659 NA 0.54 8.56 0.42 3.8e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs921968 0.608 rs678814 chr2:219359287 T/C cg02985541 chr2:219472218 PLCD4 0.45 8.65 0.42 2.09e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs4820539 1.000 rs3827316 chr22:23468538 T/C cg14186256 chr22:23484241 RTDR1 0.99 21.57 0.76 9.43e-66 Bone mineral density; LIHC cis rs1577917 0.958 rs34765423 chr6:86484448 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.09 -0.36 7.72e-12 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs1414342 chr6:8462552 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.61 0.53 1.66e-26 Motion sickness; LIHC cis rs10847980 0.590 rs12319654 chr12:123327160 C/T cg07706471 chr12:123319906 HIP1R 0.77 8.68 0.42 1.66e-16 Adiponectin levels; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg18306943 chr3:40428807 ENTPD3 0.4 6.98 0.35 1.54e-11 Renal cell carcinoma; LIHC cis rs2279817 0.863 rs2270976 chr1:18023690 A/G cg21791023 chr1:18019539 ARHGEF10L 0.6 8.49 0.42 6.23e-16 Neuroticism; LIHC cis rs477692 0.569 rs10764883 chr10:131307817 A/G cg19680672 chr10:131412579 MGMT -0.39 -5.91 -0.3 8.15e-9 Response to temozolomide; LIHC cis rs6582630 0.599 rs4882313 chr12:38454011 G/A cg26384229 chr12:38710491 ALG10B -0.45 -5.85 -0.3 1.14e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs600806 0.778 rs4970765 chr1:110009171 C/T cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.8 -0.39 7.43e-14 Intelligence (multi-trait analysis); LIHC cis rs858239 0.601 rs73272048 chr7:23152653 C/G cg23682824 chr7:23144976 KLHL7 0.46 6.88 0.35 2.83e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs17685 0.753 rs13240404 chr7:75675719 C/T cg01364799 chr7:75623366 TMEM120A 0.52 7.83 0.39 6.35e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7116495 0.737 rs7102192 chr11:71648169 G/A cg26138937 chr11:71823887 C11orf51 -0.74 -7.36 -0.37 1.42e-12 Severe influenza A (H1N1) infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05677249 chr15:77158041 SCAPER 0.33 6.05 0.31 3.9e-9 Pancreatic cancer; LIHC cis rs4906332 1.000 rs12896612 chr14:103877868 A/G cg04998671 chr14:104000505 TRMT61A -0.44 -6.12 -0.31 2.55e-9 Coronary artery disease; LIHC cis rs875971 0.862 rs801194 chr7:66028495 T/C cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.28e-34 Aortic root size; LIHC cis rs644799 0.601 rs7902 chr11:95565288 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.63 10.52 0.49 1.32e-22 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05234169 chr12:82752252 CCDC59;C12orf26 0.49 6.6 0.34 1.53e-10 Lung function (FEV1/FVC); LIHC cis rs6964587 0.626 rs409 chr7:91556355 C/T cg17063962 chr7:91808500 NA 0.6 10.73 0.5 2.44e-23 Breast cancer; LIHC cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs12479064 0.724 rs10496336 chr2:99996165 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.52 -7.17 -0.36 4.76e-12 Chronic sinus infection; LIHC cis rs2732480 0.500 rs2932093 chr12:48648271 G/T cg21466736 chr12:48725269 NA -0.71 -10.89 -0.51 6.64e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg06466757 chr4:1255808 NA -0.34 -5.78 -0.3 1.7e-8 Obesity-related traits; LIHC trans rs2727020 0.658 rs4980442 chr11:49445016 G/T cg03929089 chr4:120376271 NA -0.85 -16.46 -0.66 3.16e-45 Coronary artery disease; LIHC cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg11890956 chr21:40555474 PSMG1 0.98 13.8 0.6 9.83e-35 Cognitive function; LIHC cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg03264133 chr6:25882463 NA 0.67 8.4 0.41 1.19e-15 Intelligence (multi-trait analysis); LIHC cis rs9457247 1.000 rs393558 chr6:167397750 A/C cg12798992 chr6:167411361 FGFR1OP 0.6 10.15 0.48 2.49e-21 Crohn's disease; LIHC cis rs55882075 1.000 rs55882075 chr5:179210115 C/G cg14593053 chr5:179126677 CANX 0.43 7.76 0.39 9.65e-14 Monocyte percentage of white cells; LIHC cis rs854765 0.619 rs6502636 chr17:17983817 A/T cg04398451 chr17:18023971 MYO15A -0.64 -10.54 -0.5 1.15e-22 Total body bone mineral density; LIHC cis rs1914816 1.000 rs1914816 chr15:76546933 G/A cg03037974 chr15:76606532 NA -0.58 -5.91 -0.3 8.35e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs847649 1.000 rs847648 chr7:102553850 C/T cg18108683 chr7:102477205 FBXL13 -0.49 -7.36 -0.37 1.38e-12 Morning vs. evening chronotype; LIHC cis rs6754311 0.638 rs2322659 chr2:136555659 A/G cg15123519 chr2:136567270 LCT 0.39 7.42 0.37 9.66e-13 Mosquito bite size; LIHC cis rs12594515 0.506 rs74199860 chr15:45989190 C/T cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.75e-12 Waist circumference;Weight; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg08219700 chr8:58056026 NA 0.53 7.27 0.37 2.4e-12 Developmental language disorder (linguistic errors); LIHC cis rs7107174 1.000 rs9651768 chr11:77996020 C/T cg02023728 chr11:77925099 USP35 0.46 8.84 0.43 5.1e-17 Testicular germ cell tumor; LIHC cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.6 0.53 1.92e-26 Platelet count; LIHC cis rs9296092 0.517 rs56206922 chr6:33522567 C/T cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg21877656 chr19:58662188 ZNF329 1.07 8.51 0.42 5.37e-16 Cholesterol, total; LIHC cis rs754466 0.651 rs10824583 chr10:79619402 C/T cg17075019 chr10:79541650 NA 0.77 11.88 0.54 1.76e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8084351 0.512 rs7229129 chr18:50804372 C/T cg24270629 chr18:50823537 DCC -0.49 -7.38 -0.37 1.24e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs10504073 0.647 rs62507247 chr8:50013554 T/G cg00325661 chr8:49890786 NA 0.32 7.32 0.37 1.75e-12 Blood metabolite ratios; LIHC cis rs8016982 0.662 rs9806020 chr14:81668555 A/C cg01989461 chr14:81687754 GTF2A1 0.51 8.85 0.43 4.71e-17 Schizophrenia; LIHC cis rs9916302 0.904 rs9944411 chr17:37483599 T/C cg00129232 chr17:37814104 STARD3 0.38 6.13 0.31 2.43e-9 Glomerular filtration rate (creatinine); LIHC cis rs10463316 0.894 rs3846711 chr5:150740749 A/G cg03212797 chr5:150827313 SLC36A1 -0.44 -6.67 -0.34 1.05e-10 Metabolite levels (Pyroglutamine); LIHC cis rs10193935 1.000 rs72796507 chr2:42409840 A/G cg27598129 chr2:42591480 NA -0.75 -11.22 -0.52 4.47e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs10751667 0.643 rs10751666 chr11:941933 C/T cg06064525 chr11:970664 AP2A2 -0.55 -14.49 -0.62 2.01e-37 Alzheimer's disease (late onset); LIHC cis rs8077889 1.000 rs2342310 chr17:41866199 T/C cg26893861 chr17:41843967 DUSP3 1.03 11.15 0.52 7.78e-25 Triglycerides; LIHC cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.86 -0.3 1.11e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9611565 0.573 rs9306355 chr22:42111896 A/T cg06634786 chr22:41940651 POLR3H 0.56 6.08 0.31 3.22e-9 Vitiligo; LIHC cis rs7772486 0.790 rs2253768 chr6:146199922 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.99 -0.31 5.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3820068 0.734 rs6674806 chr1:15902656 A/G cg17385448 chr1:15911702 AGMAT 0.4 6.63 0.34 1.34e-10 Systolic blood pressure; LIHC cis rs7647973 0.592 rs6774202 chr3:49687779 T/G cg03060546 chr3:49711283 APEH 0.6 6.94 0.35 1.98e-11 Menarche (age at onset); LIHC cis rs1799949 0.965 rs6503727 chr17:41312859 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.17 0.32 1.88e-9 Menopause (age at onset); LIHC cis rs17818399 0.547 rs4952831 chr2:46761181 G/A cg02822958 chr2:46747628 ATP6V1E2 0.43 6.33 0.32 7.65e-10 Height; LIHC cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -12.6 -0.56 3.74e-30 Alzheimer's disease; LIHC cis rs9911578 1.000 rs2531734 chr17:56550804 T/C cg05425664 chr17:57184151 TRIM37 0.57 8.5 0.42 5.79e-16 Intelligence (multi-trait analysis); LIHC cis rs875971 1.000 rs7789554 chr7:65946038 A/G cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs1997103 1.000 rs2140915 chr7:55410699 G/C cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6450176 0.587 rs10471884 chr5:53344135 T/C ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.2 -0.58 1.94e-32 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs739401 0.588 rs10219272 chr11:3020789 G/A cg08508325 chr11:3079039 CARS -0.31 -6.77 -0.34 5.61e-11 Longevity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06793798 chr10:62538126 CDK1;CDC2 0.46 6.22 0.32 1.47e-9 Lung function (FEV1/FVC); LIHC cis rs4746818 1.000 rs906218 chr10:70960913 C/T cg11621586 chr10:70884670 VPS26A 0.84 13.52 0.59 1.11e-33 Left atrial antero-posterior diameter; LIHC cis rs12478296 0.792 rs6740738 chr2:243007368 A/C cg18898632 chr2:242989856 NA -0.48 -6.83 -0.35 3.89e-11 Obesity-related traits; LIHC cis rs7618501 0.633 rs2883057 chr3:49998282 C/T cg21467203 chr3:49911342 NA -0.44 -7.85 -0.39 5.53e-14 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22122414 chr8:53627067 RB1CC1 0.42 6.25 0.32 1.24e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs708547 0.581 rs6554400 chr4:57805306 A/C cg16868167 chr4:57843880 C4orf14;POLR2B -0.49 -7.09 -0.36 7.61e-12 Response to bleomycin (chromatid breaks); LIHC cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg18357526 chr6:26021779 HIST1H4A -0.54 -7.12 -0.36 6.23e-12 Blood metabolite levels; LIHC cis rs7715806 0.500 rs888788 chr5:74988336 C/T cg00601450 chr5:74908170 NA 0.59 7.12 0.36 6.53e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.37 0.45 1e-18 Bipolar disorder; LIHC cis rs6430585 0.583 rs73957037 chr2:136588031 C/A cg15123519 chr2:136567270 LCT -0.33 -5.73 -0.3 2.25e-8 Corneal structure; LIHC cis rs1801251 1.000 rs6745879 chr2:233590007 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.02 0.51 2.22e-24 Coronary artery disease; LIHC cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg13397359 chr6:42928475 GNMT 0.7 10.23 0.48 1.34e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs12887734 0.546 rs66676135 chr14:104271504 G/A cg08213375 chr14:104286397 PPP1R13B 0.53 9.08 0.44 9.01e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs13217239 0.646 rs6937880 chr6:27000236 C/T cg12292205 chr6:26970375 C6orf41 0.44 7.6 0.38 2.95e-13 Schizophrenia; LIHC cis rs8180040 0.966 rs6800271 chr3:47470787 A/T cg27129171 chr3:47204927 SETD2 -0.6 -10.68 -0.5 3.73e-23 Colorectal cancer; LIHC cis rs17106184 1.000 rs72898910 chr1:50908098 C/G cg07174182 chr1:51127561 FAF1 -0.54 -6.13 -0.31 2.46e-9 Type 2 diabetes; LIHC cis rs250677 0.687 rs185155 chr5:148455893 T/C cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs523522 0.962 rs509445 chr12:121017243 A/C cg12219531 chr12:120966889 COQ5 0.68 13.26 0.58 1.13e-32 High light scatter reticulocyte count; LIHC cis rs7772486 0.875 rs2777476 chr6:146345024 A/G cg05347473 chr6:146136440 FBXO30 0.37 6.04 0.31 4.09e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs4824093 0.610 rs13340054 chr22:50311726 G/A cg09872104 chr7:134855509 C7orf49 -0.75 -6.16 -0.32 2.05e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs9858542 0.953 rs9862080 chr3:49674458 A/G cg03060546 chr3:49711283 APEH -0.6 -7.97 -0.4 2.35e-14 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7572733 0.534 rs58374969 chr2:198764363 C/T cg00792783 chr2:198669748 PLCL1 0.48 6.93 0.35 2.1e-11 Dermatomyositis; LIHC cis rs2836974 0.666 rs11910705 chr21:40685604 C/T cg06238570 chr21:40685208 BRWD1 -0.57 -9.52 -0.46 3.13e-19 Cognitive function; LIHC cis rs8067545 0.750 rs11867585 chr17:19992607 A/G cg13482628 chr17:19912719 NA 0.48 8.04 0.4 1.5e-14 Schizophrenia; LIHC cis rs17685 0.712 rs7785025 chr7:75628101 C/T cg04592579 chr7:75616294 TMEM120A -0.4 -6.95 -0.35 1.83e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs367615 0.704 rs72804385 chr5:108848143 T/C cg17395555 chr5:108820864 NA 0.4 8.66 0.42 1.96e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs7927771 0.507 rs7119517 chr11:47675316 T/C cg20307385 chr11:47447363 PSMC3 0.75 11.33 0.52 1.75e-25 Subjective well-being; LIHC cis rs4970988 0.556 rs2280078 chr1:150600181 C/T cg17724175 chr1:150552817 MCL1 -0.53 -11.18 -0.52 6.31e-25 Urate levels; LIHC cis rs7772486 0.754 rs2328709 chr6:146106819 A/G cg05347473 chr6:146136440 FBXO30 -0.38 -6.1 -0.31 2.85e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9902453 0.817 rs2617880 chr17:28106118 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -11.78 -0.54 4.01e-27 Coffee consumption (cups per day); LIHC cis rs600806 0.778 rs11101960 chr1:110008778 C/T cg23091122 chr1:110024289 SYPL2 -0.48 -6.42 -0.33 4.59e-10 Intelligence (multi-trait analysis); LIHC cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg16325326 chr1:53192061 ZYG11B -0.41 -6.93 -0.35 2.07e-11 Monocyte count; LIHC cis rs1816752 0.905 rs11839006 chr13:25010031 T/C cg02811702 chr13:24901961 NA 0.25 6.31 0.32 8.75e-10 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10459717 chr5:6633577 NSUN2;SRD5A1 0.46 6.27 0.32 1.07e-9 Lung function (FEV1/FVC); LIHC cis rs7267979 1.000 rs2257420 chr20:25275890 C/A cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs9814567 0.806 rs4074523 chr3:134325657 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.4 -0.45 8.3e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1577917 0.710 rs9342041 chr6:86280875 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.24 0.45 2.71e-18 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg07424592 chr7:64974309 NA 0.8 9.21 0.45 3.38e-18 Diabetic kidney disease; LIHC cis rs17286411 0.777 rs4788569 chr16:71914785 A/G cg03805757 chr16:71968109 PKD1L3 0.41 5.85 0.3 1.13e-8 Blood protein levels; LIHC trans rs2579103 0.767 rs1371084 chr12:90667767 A/G cg00091569 chr3:40428383 ENTPD3 0.39 6.17 0.32 1.88e-9 Body mass index; LIHC trans rs208520 0.690 rs12198297 chr6:66714665 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.91 0.43 3.16e-17 Exhaled nitric oxide output; LIHC cis rs6840360 1.000 rs6839074 chr4:152603357 A/G cg22705602 chr4:152727874 NA 0.32 6.65 0.34 1.18e-10 Intelligence (multi-trait analysis); LIHC cis rs72387598 1 rs72387598 chr1:45922977 CAT/C cg05343316 chr1:45956843 TESK2 0.6 8.66 0.42 1.9e-16 Platelet distribution width; LIHC cis rs1801251 1.000 rs7606090 chr2:233606740 T/C cg25237894 chr2:233734115 C2orf82 0.57 11.03 0.51 2.04e-24 Coronary artery disease; LIHC cis rs2732480 0.538 rs2468943 chr12:48747249 G/T cg21466736 chr12:48725269 NA 0.57 8.99 0.44 1.7e-17 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs950169 0.881 rs34117475 chr15:85108443 T/C cg03959625 chr15:84868606 LOC388152 0.43 5.9 0.3 8.58e-9 Schizophrenia; LIHC cis rs2153535 0.580 rs6597322 chr6:8449952 T/G cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs7666738 0.830 rs7691433 chr4:98968118 A/T cg05340658 chr4:99064831 C4orf37 0.73 12.71 0.57 1.42e-30 Colonoscopy-negative controls vs population controls; LIHC cis rs7772486 0.754 rs9399567 chr6:146147295 C/T cg05347473 chr6:146136440 FBXO30 0.41 6.6 0.34 1.6e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs9505458 chr6:8479215 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs6089829 0.962 rs4809456 chr20:61660849 C/A cg03213289 chr20:61660250 NA 0.52 9.17 0.44 4.63e-18 Prostate cancer (SNP x SNP interaction); LIHC cis rs3008870 1.000 rs12740884 chr1:67459855 C/A cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs1580019 0.961 rs1868776 chr7:32494435 G/T cg06627557 chr7:32535165 LSM5;AVL9 -0.77 -11.72 -0.54 6.88e-27 Cognitive ability; LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg02951883 chr7:2050386 MAD1L1 -0.76 -13.18 -0.58 2.36e-32 Bipolar disorder and schizophrenia; LIHC cis rs4919087 0.590 rs61569149 chr10:99073879 A/G cg25902810 chr10:99078978 FRAT1 -0.6 -7.23 -0.36 3.16e-12 Monocyte count; LIHC cis rs708547 0.735 rs1277280 chr4:57866872 T/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.61 8.57 0.42 3.66e-16 Response to bleomycin (chromatid breaks); LIHC cis rs12893668 0.703 rs35026580 chr14:104042753 A/G cg19000871 chr14:103996768 TRMT61A -0.44 -7.16 -0.36 5.12e-12 Reticulocyte count; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg03571225 chr17:54991993 TRIM25 -0.42 -6.05 -0.31 3.81e-9 Electroencephalogram traits; LIHC cis rs9628987 0.500 rs11580417 chr1:8430224 G/A cg20416874 chr1:8611966 RERE 0.51 5.91 0.3 8.29e-9 Breast cancer; LIHC cis rs7312933 0.701 rs10880260 chr12:42561398 A/G cg01256987 chr12:42539512 GXYLT1 -0.43 -7.17 -0.36 4.53e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs739401 0.595 rs402806 chr11:3066432 A/G cg25174290 chr11:3078921 CARS 0.68 10.37 0.49 4.43e-22 Longevity; LIHC cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg17971929 chr21:40555470 PSMG1 0.85 10.18 0.48 1.99e-21 Cognitive function; LIHC cis rs311392 1.000 rs443599 chr8:55088048 T/C cg20636351 chr8:55087400 NA -0.41 -8.26 -0.41 3.14e-15 Pelvic organ prolapse (moderate/severe); LIHC cis rs6430585 0.528 rs309172 chr2:136674028 A/G cg25344623 chr2:136566232 LCT -0.34 -5.99 -0.31 5.25e-9 Corneal structure; LIHC cis rs11190604 1.000 rs2489047 chr10:102347028 A/G cg07080220 chr10:102295463 HIF1AN 0.53 7.64 0.38 2.19e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs4878497 0.646 rs2068116 chr9:32435978 C/T cg14296220 chr9:32431791 ACO1 0.58 10.05 0.48 5.58e-21 Inflammatory skin disease; LIHC cis rs1568889 1.000 rs12802157 chr11:28060285 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.81 0.35 4.36e-11 Bipolar disorder; LIHC cis rs7412746 0.566 rs11204743 chr1:150890406 A/T cg17724175 chr1:150552817 MCL1 0.42 8.19 0.41 5.08e-15 Melanoma; LIHC cis rs9816226 0.938 rs73052046 chr3:185832414 C/T cg00760338 chr3:185826511 ETV5 -0.7 -6.18 -0.32 1.81e-9 Obesity;Body mass index; LIHC cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg03452623 chr4:187889614 NA 0.31 8.06 0.4 1.26e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs7523273 0.606 rs2281289 chr1:207978916 C/T cg22525895 chr1:207977042 MIR29B2 -0.6 -10.04 -0.48 5.85e-21 Schizophrenia; LIHC cis rs965469 0.947 rs1854834 chr20:3376619 C/T cg25506879 chr20:3388711 C20orf194 -0.57 -6.81 -0.35 4.48e-11 IFN-related cytopenia; LIHC cis rs4561483 0.831 rs2018199 chr16:11940968 C/T cg08843971 chr16:11963173 GSPT1 -0.31 -6.07 -0.31 3.48e-9 Testicular germ cell tumor; LIHC cis rs10744422 1.000 rs7294991 chr12:123286780 C/T cg07706471 chr12:123319906 HIP1R -0.6 -7.43 -0.37 8.64e-13 Schizophrenia; LIHC trans rs72960926 0.744 rs11754787 chr6:74915037 A/T cg07247405 chr1:2484626 LOC115110 0.52 6.04 0.31 4.09e-9 Metabolite levels (MHPG); LIHC cis rs8017423 0.967 rs11627429 chr14:90689232 G/A cg04374321 chr14:90722782 PSMC1 -0.74 -13.99 -0.6 1.75e-35 Mortality in heart failure; LIHC cis rs8044995 0.563 rs3785113 chr16:68369213 T/C cg05110241 chr16:68378359 PRMT7 -0.87 -10.12 -0.48 3.17e-21 Schizophrenia; LIHC cis rs11792861 0.816 rs3818932 chr9:111664178 T/C cg05043794 chr9:111880884 C9orf5 -0.31 -7.22 -0.36 3.39e-12 Menarche (age at onset); LIHC cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.65e-9 Menopause (age at onset); LIHC cis rs3736485 0.934 rs17609666 chr15:51858038 G/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1801251 1.000 rs2305137 chr2:233712049 G/A cg25237894 chr2:233734115 C2orf82 -0.58 -11.44 -0.53 6.94e-26 Coronary artery disease; LIHC cis rs796364 0.806 rs11689664 chr2:201099961 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.8 -8.98 -0.44 1.8e-17 Schizophrenia; LIHC cis rs9733 0.628 rs72700895 chr1:150626029 C/T cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs4716602 0.596 rs34977094 chr7:156160864 C/T cg16983916 chr7:156159713 NA -0.32 -5.71 -0.3 2.43e-8 Anti-saccade response; LIHC cis rs7465272 1.000 rs36050651 chr8:143681796 A/G cg10104451 chr8:143696006 ARC -0.49 -6.34 -0.32 7.1e-10 Bipolar disorder and schizophrenia; LIHC cis rs3784262 1.000 rs4646638 chr15:58248783 C/T cg12031962 chr15:58353849 ALDH1A2 0.31 6.2 0.32 1.6e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs2239547 0.657 rs7638524 chr3:52874861 G/A cg18404041 chr3:52824283 ITIH1 -0.42 -5.88 -0.3 9.64e-9 Schizophrenia; LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.67 -0.34 1.04e-10 Total body bone mineral density; LIHC cis rs2084898 0.891 rs504236 chr11:120000263 T/C cg13907859 chr11:120009124 TRIM29 -0.52 -6.42 -0.33 4.67e-10 Stroke (pediatric); LIHC trans rs10506458 0.834 rs12426893 chr12:63388120 G/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.59 -0.5 7.59e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs1005277 0.505 rs719569 chr10:38154415 T/G cg00409905 chr10:38381863 ZNF37A 0.55 9.5 0.46 3.79e-19 Extrinsic epigenetic age acceleration; LIHC cis rs55665837 0.540 rs7938266 chr11:14709324 A/G cg16394018 chr11:14927549 NA 0.4 5.72 0.3 2.29e-8 Vitamin D levels; LIHC cis rs986417 0.786 rs76632048 chr14:60846934 G/A cg27398547 chr14:60952738 C14orf39 -0.79 -9.02 -0.44 1.36e-17 Gut microbiota (bacterial taxa); LIHC trans rs2727020 0.595 rs10466496 chr11:49501514 C/T cg18944383 chr4:111397179 ENPEP 0.25 6.33 0.32 7.77e-10 Coronary artery disease; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg03354898 chr7:1950403 MAD1L1 -0.37 -5.74 -0.3 2.1e-8 Bipolar disorder and schizophrenia; LIHC cis rs712039 0.652 rs712038 chr17:35762557 G/A cg16670864 chr17:35848621 DUSP14 0.35 5.85 0.3 1.15e-8 Tuberculosis; LIHC cis rs8078723 1.000 rs3826331 chr17:38150492 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.6 9.85 0.47 2.61e-20 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6570726 0.738 rs7746330 chr6:145899257 A/C cg13319975 chr6:146136371 FBXO30 -0.42 -6.66 -0.34 1.11e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7919006 1.000 rs7901229 chr10:76804824 A/G cg01390419 chr10:76803856 DUPD1 0.48 7.65 0.38 2.09e-13 Weight; LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg12143784 chr7:64541923 NA 0.37 6.42 0.33 4.55e-10 Calcium levels; LIHC cis rs9640161 0.742 rs11983355 chr7:150016697 A/C cg17279839 chr7:150038598 RARRES2 0.51 10.79 0.5 1.48e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs4660306 1.000 rs2993259 chr1:46001550 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.56 -6.87 -0.35 3.08e-11 Homocysteine levels; LIHC cis rs74181299 0.819 rs2723086 chr2:65297686 C/T cg05010058 chr2:65284262 CEP68 0.39 6.63 0.34 1.32e-10 Pulse pressure; LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.567 rs1182191 chr7:2869364 A/T cg13628971 chr7:2884303 GNA12 0.39 5.82 0.3 1.36e-8 Height; LIHC cis rs760805 0.900 rs1005733 chr1:25261960 T/A cg22509179 chr1:25234806 RUNX3 -0.38 -8.09 -0.4 1.06e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs634534 0.561 rs613924 chr11:65769295 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.98 0.31 5.53e-9 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs6762477 0.748 rs9831967 chr3:50217234 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.45 -7.15 -0.36 5.46e-12 Menarche (age at onset); LIHC cis rs72781680 0.821 rs116583405 chr2:24208221 T/C cg08917208 chr2:24149416 ATAD2B 0.62 6.28 0.32 1.05e-9 Lymphocyte counts; LIHC cis rs9948 0.655 rs62152785 chr2:97459403 A/T cg01990225 chr2:97406019 LMAN2L -0.74 -6.49 -0.33 3.08e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.56 0.62 1.09e-37 Prudent dietary pattern; LIHC cis rs425277 1.000 rs427811 chr1:2075560 T/G cg24578937 chr1:2090814 PRKCZ 0.5 8.84 0.43 5.06e-17 Height; LIHC cis rs7727544 0.836 rs10463892 chr5:131598705 T/C cg24060327 chr5:131705240 SLC22A5 -0.51 -5.81 -0.3 1.4e-8 Blood metabolite levels; LIHC trans rs11165623 0.564 rs6593611 chr1:97001996 T/C cg10631902 chr5:14652156 NA -0.29 -6.62 -0.34 1.36e-10 Hip circumference;Waist circumference; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.52 0.56 7.34e-30 Prudent dietary pattern; LIHC cis rs2979489 0.891 rs2979498 chr8:30375251 T/A cg26383811 chr8:30366931 RBPMS -0.7 -10.95 -0.51 3.89e-24 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs1023500 0.505 rs134891 chr22:42675882 T/C cg04733989 chr22:42467013 NAGA 0.43 6.54 0.33 2.22e-10 Schizophrenia; LIHC cis rs1697139 0.563 rs6859520 chr5:66529020 C/T cg16691251 chr5:66510806 NA 0.45 5.86 0.3 1.09e-8 Breast cancer; LIHC cis rs67981189 0.572 rs2810077 chr14:71363814 A/G cg15816911 chr14:71606274 NA -0.37 -5.98 -0.31 5.54e-9 Schizophrenia; LIHC cis rs4819052 0.851 rs2838858 chr21:46681093 T/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.71 0.38 1.35e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.79 0.5 1.49e-23 Platelet count; LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg00684032 chr4:1343700 KIAA1530 0.36 5.82 0.3 1.32e-8 Obesity-related traits; LIHC cis rs9443189 0.526 rs9359132 chr6:76289553 G/A cg01950844 chr6:76311363 SENP6 0.9 11.22 0.52 4.37e-25 Prostate cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg26144629 chr1:207926000 CD46 -0.47 -6.49 -0.33 3.02e-10 Longevity; LIHC cis rs13161895 1.000 rs248318 chr5:179430530 C/T cg06664874 chr5:179499304 RNF130 0.58 7.13 0.36 5.93e-12 LDL cholesterol; LIHC cis rs8083850 0.635 rs12968567 chr18:50873468 T/C cg24270629 chr18:50823537 DCC 0.53 8.03 0.4 1.53e-14 Intelligence (multi-trait analysis); LIHC trans rs4820294 0.646 rs9622675 chr22:38053665 G/T cg19894588 chr14:64061835 NA -0.47 -7.4 -0.37 1.05e-12 Fat distribution (HIV); LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg15382696 chr6:118971807 C6orf204 -0.69 -6.85 -0.35 3.35e-11 Diastolic blood pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04249525 chr7:152373324 XRCC2 0.42 6.14 0.32 2.35e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs11689435 0.925 rs71401198 chr2:218344355 G/T cg13544946 chr9:35729779 TLN1 -0.46 -6.52 -0.33 2.57e-10 Metabolite levels (MHPG); LIHC cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg11890956 chr21:40555474 PSMG1 1.03 14.59 0.62 7.75e-38 Cognitive function; LIHC cis rs2282526 0.587 rs91424 chr21:44921161 A/G cg21573476 chr21:45109991 RRP1B 0.47 7.93 0.39 3.15e-14 Mean corpuscular hemoglobin; LIHC cis rs4555082 0.957 rs3825762 chr14:105752404 T/C cg13114125 chr14:105738426 BRF1 -0.7 -9.33 -0.45 1.35e-18 Mean platelet volume;Platelet distribution width; LIHC trans rs11157436 1.000 rs2293731 chr14:22616834 C/G cg13567813 chr19:50879636 NR1H2 0.43 6.19 0.32 1.68e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs853679 0.517 rs868987 chr6:28110148 A/G cg16479474 chr6:28041457 NA -0.45 -6.41 -0.33 4.74e-10 Depression; LIHC cis rs763014 0.932 rs2384972 chr16:674424 G/A cg09263875 chr16:632152 PIGQ 0.61 10.64 0.5 4.85e-23 Height; LIHC cis rs10464366 0.746 rs34792397 chr7:39146331 G/A cg15212455 chr7:39170539 POU6F2 0.43 7.64 0.38 2.24e-13 IgG glycosylation; LIHC cis rs7927771 0.929 rs66749409 chr11:47568074 C/T cg18512352 chr11:47633146 NA -0.26 -6.06 -0.31 3.5e-9 Subjective well-being; LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.31 -0.32 8.81e-10 Total body bone mineral density; LIHC cis rs2228479 0.850 rs1800331 chr16:89858417 C/A cg04013166 chr16:89971882 TCF25 0.48 5.81 0.3 1.46e-8 Skin colour saturation; LIHC cis rs920590 0.758 rs62496731 chr8:19659543 C/G cg01411142 chr8:19674711 INTS10 0.53 8.06 0.4 1.28e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs4654899 1.000 rs61117207 chr1:21394374 A/C cg08539965 chr1:21396338 EIF4G3 0.33 5.75 0.3 1.96e-8 Superior frontal gyrus grey matter volume; LIHC cis rs611744 0.967 rs635219 chr8:109229243 C/T cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs11671005 0.735 rs34511020 chr19:58921296 A/G cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs34779708 0.931 rs35997236 chr10:35376690 C/T cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1008375 0.966 rs2010053 chr4:17583806 A/C cg02297831 chr4:17616191 MED28 0.48 7.24 0.36 2.99e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7089973 0.604 rs61596353 chr10:116597763 T/C cg03647239 chr10:116582469 FAM160B1 0.44 6.58 0.34 1.74e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.68 0.38 1.66e-13 Height; LIHC cis rs9871864 0.868 rs13094888 chr3:20350308 G/C cg00235661 chr3:20228976 SGOL1 -0.31 -5.9 -0.3 8.9e-9 Behavioural disinhibition (generation interaction); LIHC cis rs2050392 0.858 rs2250569 chr10:30698914 G/C cg25182066 chr10:30743637 MAP3K8 -0.44 -7.12 -0.36 6.52e-12 Inflammatory bowel disease; LIHC cis rs4969178 0.930 rs2292644 chr17:76394449 C/T cg20026190 chr17:76395443 PGS1 0.45 7.15 0.36 5.19e-12 HDL cholesterol levels; LIHC cis rs2072499 0.932 rs2736613 chr1:156196016 T/C cg25208724 chr1:156163844 SLC25A44 0.86 14.19 0.61 2.98e-36 Testicular germ cell tumor; LIHC cis rs7258465 1.000 rs2278238 chr19:18576484 T/C cg10790698 chr19:18539756 SSBP4 -0.35 -7.18 -0.36 4.37e-12 Breast cancer; LIHC cis rs782590 0.967 rs17798852 chr2:55805172 A/C cg18811423 chr2:55921094 PNPT1 0.93 15.18 0.63 3.68e-40 Metabolic syndrome; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg20341384 chr10:131568735 NA 0.43 6.61 0.34 1.44e-10 Immature fraction of reticulocytes; LIHC cis rs6748734 0.948 rs4471886 chr2:241838622 T/C cg20140201 chr2:241835670 C2orf54 -0.54 -8.33 -0.41 2.05e-15 Urinary metabolites; LIHC cis rs9549367 0.789 rs3861720 chr13:113906097 A/G cg00898013 chr13:113819073 PROZ -0.42 -7.18 -0.36 4.24e-12 Platelet distribution width; LIHC cis rs12701220 0.689 rs12701824 chr7:1102364 G/A cg26769984 chr7:1090371 C7orf50 0.59 5.79 0.3 1.61e-8 Bronchopulmonary dysplasia; LIHC cis rs367615 0.704 rs60538082 chr5:108829101 A/G cg17395555 chr5:108820864 NA 0.4 8.76 0.43 9.1e-17 Colorectal cancer (SNP x SNP interaction); LIHC cis rs7945705 0.846 rs2742540 chr11:8899528 A/G cg12365402 chr11:9010492 NRIP3 0.26 6.71 0.34 7.92e-11 Hemoglobin concentration; LIHC cis rs13343954 0.518 rs2216594 chr19:33533258 G/A cg17764715 chr19:33622953 WDR88 0.49 6.87 0.35 2.96e-11 Colorectal cancer; LIHC cis rs8067354 0.645 rs2645489 chr17:57883371 T/G cg13753209 chr17:57696993 CLTC 0.73 11.68 0.53 9.69e-27 Hemoglobin concentration; LIHC cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg05368731 chr17:41323189 NBR1 0.72 12.12 0.55 2.21e-28 Menopause (age at onset); LIHC cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.53 7.38 0.37 1.19e-12 Schizophrenia; LIHC cis rs3540 0.533 rs4932342 chr15:90982923 C/T cg22089800 chr15:90895588 ZNF774 0.59 8.05 0.4 1.34e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs4727027 0.933 rs1044358 chr7:148879951 C/A cg23583168 chr7:148888333 NA -0.74 -10.55 -0.5 1.02e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs11628318 0.614 rs1190335 chr14:103111358 T/C cg12046867 chr14:103022105 NA -0.43 -6.8 -0.35 4.54e-11 Platelet count; LIHC cis rs4908768 0.725 rs11121214 chr1:8728665 C/T cg20416874 chr1:8611966 RERE 0.5 7.08 0.36 8.18e-12 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg12311636 chr6:118886798 C6orf204 -0.56 -6.41 -0.33 4.89e-10 Diastolic blood pressure; LIHC cis rs1008375 0.932 rs6814465 chr4:17659034 C/T cg16339924 chr4:17578868 LAP3 0.53 7.01 0.35 1.27e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1862618 0.525 rs2662019 chr5:56263104 A/G cg12311346 chr5:56204834 C5orf35 0.59 7.38 0.37 1.21e-12 Initial pursuit acceleration; LIHC cis rs9790314 0.543 rs1349352 chr3:161118486 C/T cg03342759 chr3:160939853 NMD3 -0.54 -8.53 -0.42 4.75e-16 Morning vs. evening chronotype; LIHC trans rs208515 0.556 rs10455193 chr6:66691456 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.86 0.43 4.37e-17 Exhaled nitric oxide levels; LIHC cis rs8180040 0.800 rs62248905 chr3:47274082 A/G cg16586182 chr3:47516702 SCAP 0.51 9.01 0.44 1.45e-17 Colorectal cancer; LIHC cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg01411255 chr17:61851458 DDX42;CCDC47 -0.56 -9.33 -0.45 1.32e-18 Prudent dietary pattern; LIHC cis rs734999 0.505 rs4445406 chr1:2539400 T/C cg18854424 chr1:2615690 NA 0.33 7.22 0.36 3.33e-12 Ulcerative colitis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13048808 chr17:11924852 MAP2K4 0.46 6.17 0.32 1.96e-9 Lung function (FEV1/FVC); LIHC cis rs1577917 0.740 rs9450302 chr6:86289673 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.33 6.01 0.31 4.78e-9 Response to antipsychotic treatment; LIHC cis rs801193 0.613 rs2659900 chr7:66184443 G/C cg12463550 chr7:65579703 CRCP 0.4 5.78 0.3 1.71e-8 Aortic root size; LIHC cis rs12188164 0.525 rs1114665 chr5:452247 C/T cg26072250 chr5:443457 EXOC3;C5orf55 0.44 6.38 0.33 5.76e-10 Cystic fibrosis severity; LIHC cis rs74417235 0.684 rs7723312 chr5:154053249 A/G cg19735590 chr5:154026979 NA -0.48 -5.97 -0.31 6.07e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs651907 0.557 rs12629954 chr3:101360623 C/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.18 -0.32 1.81e-9 Colorectal cancer; LIHC cis rs10791323 0.633 rs2171006 chr11:133728323 T/C cg15485101 chr11:133734466 NA 0.25 5.89 0.3 9.42e-9 Childhood ear infection; LIHC cis rs6952808 0.825 rs34922657 chr7:1938655 C/T cg14004847 chr7:1930337 MAD1L1 -0.49 -6.87 -0.35 3.09e-11 Bipolar disorder and schizophrenia; LIHC cis rs763121 0.925 rs4821797 chr22:39016182 T/C cg06022373 chr22:39101656 GTPBP1 0.72 14.4 0.61 4.38e-37 Menopause (age at onset); LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg07677032 chr17:61819896 STRADA 0.43 6.19 0.32 1.77e-9 Prudent dietary pattern; LIHC cis rs9616064 0.506 rs2542038 chr22:47059282 C/T cg05621596 chr22:47072043 GRAMD4 -0.59 -9.47 -0.46 4.78e-19 Urate levels in obese individuals; LIHC cis rs1552244 0.882 rs2130813 chr3:10038706 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.19 -0.45 3.81e-18 Alzheimer's disease; LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg09455208 chr3:40491958 NA 0.4 8.07 0.4 1.21e-14 Renal cell carcinoma; LIHC cis rs4332037 0.722 rs7788921 chr7:1915282 C/A cg23422044 chr7:1970798 MAD1L1 -0.69 -10.52 -0.49 1.29e-22 Bipolar disorder; LIHC cis rs4908768 0.501 rs12756257 chr1:8616933 C/A cg20416874 chr1:8611966 RERE -0.68 -14.82 -0.63 1.02e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs921968 0.510 rs620887 chr2:219465594 C/A cg02176678 chr2:219576539 TTLL4 0.53 7.36 0.37 1.39e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs72627123 0.582 rs62005101 chr14:74500585 A/T cg05179529 chr14:74551516 LIN52;ALDH6A1 0.49 6.43 0.33 4.3e-10 Morning vs. evening chronotype; LIHC cis rs80282103 0.618 rs1079390 chr10:1161653 C/A cg08668510 chr10:1095578 IDI1 0.63 6.08 0.31 3.13e-9 Glomerular filtration rate (creatinine); LIHC cis rs769267 0.930 rs10414830 chr19:19562332 C/T cg03709012 chr19:19516395 GATAD2A 1.02 18.35 0.7 7.4e-53 Tonsillectomy; LIHC cis rs2075371 0.796 rs10954440 chr7:134005657 C/T cg20476274 chr7:133979776 SLC35B4 0.68 9.19 0.44 3.98e-18 Mean platelet volume; LIHC cis rs921968 0.643 rs4674324 chr2:219523433 T/G cg18887096 chr2:219472410 PLCD4 0.39 6.76 0.34 6.11e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9902453 0.904 rs7219456 chr17:28374112 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs311392 0.934 rs376589 chr8:55088289 G/A cg11783602 chr8:55087084 NA -0.33 -6.5 -0.33 2.82e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs6088580 0.505 rs6058106 chr20:33278255 T/C cg07148914 chr20:33460835 GGT7 -0.55 -7.74 -0.39 1.13e-13 Glomerular filtration rate (creatinine); LIHC cis rs2033711 0.840 rs10423138 chr19:58928302 T/C cg26874164 chr19:58962979 ZNF324B 0.42 5.8 0.3 1.48e-8 Uric acid clearance; LIHC cis rs7520050 0.966 rs12411269 chr1:46271052 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.98 0.31 5.65e-9 Red blood cell count;Reticulocyte count; LIHC cis rs77633900 0.614 rs157757 chr15:76855927 G/C cg21673338 chr15:77095150 SCAPER -0.5 -6.81 -0.35 4.45e-11 Non-glioblastoma glioma;Glioma; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg06558623 chr16:89946397 TCF25 1.01 15.53 0.64 1.55e-41 Skin colour saturation; LIHC cis rs4407350 1.000 rs4823331 chr22:44923082 T/C cg26276947 chr22:44892394 LDOC1L 0.33 6.01 0.31 4.83e-9 Intelligence (multi-trait analysis); LIHC trans rs6570726 0.516 rs10457779 chr6:145736663 C/T cg20452738 chr1:226828650 ITPKB -0.21 -6.09 -0.31 3.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10791323 0.559 rs10750549 chr11:133730820 A/G cg06766960 chr11:133703094 NA -0.67 -11.31 -0.52 2.06e-25 Childhood ear infection; LIHC cis rs7408868 0.908 rs45591935 chr19:15277006 T/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.77 -0.3 1.8e-8 Pulse pressure; LIHC cis rs9457247 1.000 rs402749 chr6:167386104 C/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs716804 0.740 rs2044143 chr11:10286758 A/G cg01453529 chr11:10209919 SBF2 -0.29 -5.87 -0.3 1.01e-8 Neuroticism; LIHC cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg19723775 chr5:179050963 HNRNPH1 0.41 6.44 0.33 4.1e-10 Lung cancer; LIHC cis rs892961 0.899 rs3650 chr17:75415835 T/C cg05865280 chr17:75406074 SEPT9 0.63 12.71 0.57 1.36e-30 Airflow obstruction; LIHC trans rs2797160 0.904 rs1739370 chr6:126011231 C/T cg05039488 chr6:79577232 IRAK1BP1 0.5 6.93 0.35 2.05e-11 Endometrial cancer; LIHC trans rs9929218 1.000 rs35069703 chr16:68789445 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.64 -9.54 -0.46 2.78e-19 Colorectal cancer; LIHC cis rs6964587 1.000 rs12333563 chr7:91667326 G/A cg17063962 chr7:91808500 NA 1.01 19.44 0.72 3.27e-57 Breast cancer; LIHC cis rs2952156 1.000 rs2643195 chr17:37853118 A/G cg00129232 chr17:37814104 STARD3 -0.51 -9.36 -0.45 1.07e-18 Asthma; LIHC cis rs7786877 0.521 rs4729607 chr7:100326744 T/A cg16850897 chr7:100343110 ZAN -0.44 -6.41 -0.33 4.76e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17253792 0.822 rs78261053 chr14:56061784 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs6430585 0.583 rs7561565 chr2:136640787 A/C cg15123519 chr2:136567270 LCT -0.35 -5.86 -0.3 1.08e-8 Corneal structure; LIHC cis rs11583043 1.000 rs11584222 chr1:101480110 G/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.83 0.3 1.3e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs7395662 0.591 rs10838972 chr11:48611400 A/G cg15704280 chr7:45808275 SEPT13 -0.47 -7.01 -0.35 1.29e-11 HDL cholesterol; LIHC cis rs7412746 0.658 rs6660845 chr1:150841066 G/A cg15448220 chr1:150897856 SETDB1 0.39 5.8 0.3 1.51e-8 Melanoma; LIHC cis rs8062405 1.000 rs7498555 chr16:28893571 T/C cg00204512 chr16:28754710 NA 0.36 6.46 0.33 3.53e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10876993 0.890 rs774891 chr12:58068571 G/A cg15848620 chr12:58087721 OS9 -0.6 -8.11 -0.4 8.91e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs7095944 0.584 rs11245347 chr10:126427037 G/T cg20435097 chr10:126320824 FAM53B 0.36 5.98 0.31 5.7e-9 Asthma; LIHC cis rs2242116 0.727 rs4683298 chr3:46966387 C/G cg23352942 chr3:46931381 PTH1R -0.27 -6.99 -0.35 1.44e-11 Birth weight; LIHC cis rs56104184 0.725 rs4347731 chr19:49385154 A/G cg15549821 chr19:49342101 PLEKHA4 -0.79 -6.61 -0.34 1.47e-10 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs11098699 0.821 rs4833886 chr4:124206263 A/C cg09941581 chr4:124220074 SPATA5 0.32 6.39 0.33 5.31e-10 Mosquito bite size; LIHC cis rs7917772 0.508 rs2252147 chr10:104467774 G/A cg22532475 chr10:104410764 TRIM8 -0.36 -6.41 -0.33 4.97e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1577917 0.958 rs13207173 chr6:86457522 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.98 -0.31 5.56e-9 Response to antipsychotic treatment; LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg08219700 chr8:58056026 NA 0.49 6.61 0.34 1.47e-10 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.965 rs8176198 chr17:41230537 A/T cg23758822 chr17:41437982 NA 0.84 15.39 0.64 5.83e-41 Menopause (age at onset); LIHC cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg20684491 chr1:25596433 NA 0.29 5.9 0.3 8.58e-9 Erythrocyte sedimentation rate; LIHC cis rs9368481 0.524 rs12530345 chr6:26884243 T/C cg12292205 chr6:26970375 C6orf41 0.42 7.12 0.36 6.56e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs66573146 0.831 rs56031152 chr4:6973832 C/A cg15105060 chr4:7024189 TBC1D14 -0.74 -6.3 -0.32 9.22e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9733 0.596 rs12086630 chr1:150650955 T/C cg13175981 chr1:150552382 MCL1 -0.44 -6.16 -0.32 2.07e-9 Tonsillectomy; LIHC cis rs11148252 0.500 rs342768 chr13:53208882 C/T cg12458913 chr13:53173898 NA 0.44 7.03 0.36 1.1e-11 Lewy body disease; LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.42 -0.41 1.02e-15 Lymphocyte counts; LIHC cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg12463550 chr7:65579703 CRCP 0.67 7.02 0.35 1.23e-11 Diabetic kidney disease; LIHC cis rs6456156 0.586 rs12529876 chr6:167461501 G/A cg23791538 chr6:167370224 RNASET2 -0.53 -8.64 -0.42 2.18e-16 Primary biliary cholangitis; LIHC cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg11644478 chr21:40555479 PSMG1 0.79 9.9 0.47 1.7e-20 Cognitive function; LIHC cis rs6669384 0.774 rs4844624 chr1:208035446 A/G cg22525895 chr1:207977042 MIR29B2 -0.53 -5.84 -0.3 1.21e-8 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg22528358 chr1:107598549 PRMT6 -0.71 -11.85 -0.54 2.22e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs651907 0.557 rs3806654 chr3:101396529 G/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.85 0.57 4.29e-31 Colorectal cancer; LIHC cis rs2153535 0.580 rs6927589 chr6:8456632 A/G cg07606381 chr6:8435919 SLC35B3 -0.82 -12.37 -0.56 2.72e-29 Motion sickness; LIHC cis rs10916814 0.632 rs1890003 chr1:20899101 T/C cg24502330 chr1:20914028 CDA -0.3 -6.7 -0.34 8.63e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1538970 0.962 rs9429072 chr1:45810091 C/T cg24296786 chr1:45957014 TESK2 0.5 7.59 0.38 3.05e-13 Platelet count; LIHC cis rs10744422 0.925 rs2292132 chr12:123332834 T/C cg25930673 chr12:123319894 HIP1R -0.93 -12.35 -0.56 3.04e-29 Schizophrenia; LIHC cis rs2730245 0.505 rs1188956 chr7:158690576 G/A cg23730037 chr7:158596552 ESYT2 -0.41 -6.31 -0.32 8.88e-10 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01250699 chr8:22225185 SLC39A14 0.4 6.06 0.31 3.67e-9 Pancreatic cancer; LIHC cis rs1707322 1.000 rs7527079 chr1:46413450 C/G cg03146154 chr1:46216737 IPP 0.48 7.84 0.39 5.74e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6754311 0.597 rs2278544 chr2:136546110 A/G cg07305463 chr2:136567211 LCT 0.37 6.55 0.33 2.1e-10 Mosquito bite size; LIHC cis rs6089584 0.853 rs1746280 chr20:60577821 C/G cg12751644 chr20:60527061 NA -0.36 -5.88 -0.3 9.74e-9 Body mass index; LIHC cis rs875971 1.000 rs10244498 chr7:66116056 A/G cg11764359 chr7:65958608 NA 0.82 14.43 0.62 3.29e-37 Aortic root size; LIHC cis rs7551222 0.752 rs11240754 chr1:204477977 A/G cg20240347 chr1:204465584 NA -0.35 -7.48 -0.37 6.51e-13 Schizophrenia; LIHC cis rs61712019 0.679 rs13029065 chr2:77721076 G/A cg11252801 chr2:77748917 LRRTM4 0.56 7.73 0.39 1.2e-13 Schizophrenia; LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg08280861 chr8:58055591 NA 0.56 6.74 0.34 6.9e-11 Developmental language disorder (linguistic errors); LIHC cis rs11758351 0.866 rs56186759 chr6:26207181 C/T cg16070018 chr6:26224392 HIST1H3E 0.6 7.53 0.38 4.45e-13 Gout;Renal underexcretion gout; LIHC trans rs11098499 0.909 rs35165976 chr4:120325630 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs780096 0.778 rs780094 chr2:27741237 C/T cg22903471 chr2:27725779 GCKR 0.31 6.05 0.31 3.86e-9 Total body bone mineral density; LIHC cis rs1559088 0.948 rs6510346 chr19:33598526 T/A cg27124370 chr19:33622961 WDR88 0.52 8.21 0.41 4.63e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs72627123 0.867 rs80083802 chr14:74456996 C/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.46 0.42 8.11e-16 Morning vs. evening chronotype; LIHC cis rs2274273 0.837 rs56949365 chr14:55790078 T/C cg01864836 chr14:55583639 NA -0.37 -6.57 -0.33 1.9e-10 Protein biomarker; LIHC cis rs2075371 0.796 rs35336643 chr7:134010640 G/A cg20476274 chr7:133979776 SLC35B4 0.72 10.0 0.48 8.14e-21 Mean platelet volume; LIHC cis rs9814567 0.806 rs4955534 chr3:134319723 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11958404 1.000 rs72816523 chr5:157403168 G/C cg05962755 chr5:157440814 NA 1.07 11.91 0.54 1.38e-27 IgG glycosylation; LIHC cis rs55665837 0.520 rs10766189 chr11:14733923 G/A cg00085434 chr11:14927489 NA 0.41 5.81 0.3 1.41e-8 Vitamin D levels; LIHC cis rs58235267 0.553 rs1025132 chr2:63360639 G/A cg17519650 chr2:63277830 OTX1 0.58 8.87 0.43 4.22e-17 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs561341 0.663 rs72821936 chr17:30224068 C/G cg13647721 chr17:30228624 UTP6 0.79 9.13 0.44 5.94e-18 Hip circumference adjusted for BMI; LIHC cis rs769267 0.896 rs10410664 chr19:19556651 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.95 0.31 6.6e-9 Tonsillectomy; LIHC trans rs1814175 0.754 rs10839453 chr11:49955815 A/T cg18944383 chr4:111397179 ENPEP 0.27 6.94 0.35 2.01e-11 Height; LIHC cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg13271783 chr10:134563150 INPP5A -0.6 -7.16 -0.36 5.03e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1577917 0.958 rs10944136 chr6:86448499 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.36 -0.41 1.63e-15 Response to antipsychotic treatment; LIHC cis rs6051080 1 rs6051080 chr20:25975674 A/G cg13962466 chr20:25176127 ENTPD6 0.42 5.89 0.3 9.41e-9 Colorectal or endometrial cancer; LIHC cis rs9733 0.596 rs6690725 chr1:150632322 T/C cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs9911578 0.874 rs302865 chr17:56756977 A/G cg12560992 chr17:57184187 TRIM37 0.95 17.38 0.68 6.34e-49 Intelligence (multi-trait analysis); LIHC cis rs1555322 0.530 rs2275275 chr20:33872311 G/C cg03689076 chr20:33865952 NA 0.58 6.68 0.34 9.81e-11 Attention deficit hyperactivity disorder; LIHC cis rs4650994 0.571 rs11588907 chr1:178509462 C/T cg05350800 chr1:178550844 NA -0.3 -6.41 -0.33 4.84e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs11122272 0.705 rs2790879 chr1:231534389 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -9.9 -0.47 1.73e-20 Hemoglobin concentration; LIHC cis rs1799949 0.965 rs799910 chr17:41279561 G/C cg05368731 chr17:41323189 NBR1 0.68 11.16 0.52 7.19e-25 Menopause (age at onset); LIHC cis rs611744 0.967 rs655722 chr8:109197541 A/T cg21045802 chr8:109455806 TTC35 0.44 7.52 0.38 4.9e-13 Dupuytren's disease; LIHC cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg00166722 chr3:10149974 C3orf24 0.47 5.76 0.3 1.86e-8 Alzheimer's disease; LIHC cis rs933688 0.938 rs10063683 chr5:90714595 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.37 0.66 6.68e-45 Smoking behavior; LIHC cis rs7124681 0.584 rs7950674 chr11:47871017 T/C cg20307385 chr11:47447363 PSMC3 0.71 10.58 0.5 7.85e-23 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs11711311 1.000 rs13070720 chr3:113473754 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.26 -0.37 2.56e-12 IgG glycosylation; LIHC trans rs916888 0.773 rs538628 chr17:44787313 G/C cg26692224 chr17:62915920 LRRC37A3 -0.71 -6.81 -0.35 4.44e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2836950 0.501 rs2836985 chr21:40701169 A/G cg06238570 chr21:40685208 BRWD1 -0.46 -7.47 -0.37 6.88e-13 Menarche (age at onset); LIHC cis rs798554 0.679 rs798499 chr7:2792013 G/A cg19717773 chr7:2847554 GNA12 -0.4 -7.19 -0.36 4.13e-12 Height; LIHC cis rs17106184 1.000 rs3789588 chr1:51266523 G/A cg07174182 chr1:51127561 FAF1 -0.65 -6.99 -0.35 1.46e-11 Type 2 diabetes; LIHC cis rs4561483 0.549 rs33657 chr16:11969724 G/C cg08843971 chr16:11963173 GSPT1 -0.39 -7.61 -0.38 2.67e-13 Testicular germ cell tumor; LIHC cis rs9457247 0.612 rs2237273 chr6:167443017 T/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.62 -0.42 2.61e-16 Crohn's disease; LIHC cis rs17376456 0.825 rs17372615 chr5:93124768 C/T cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs765787 0.530 rs4774542 chr15:45526026 A/C cg25801113 chr15:45476975 SHF -0.38 -6.34 -0.32 7.2e-10 Uric acid levels; LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.54 0.38 4.18e-13 Height; LIHC cis rs2976388 0.647 rs2572906 chr8:143798269 G/A cg13446199 chr8:143762866 PSCA -0.2 -5.76 -0.3 1.85e-8 Urinary tract infection frequency; LIHC cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg16606324 chr3:10149918 C3orf24 0.55 5.92 0.3 7.84e-9 Alzheimer's disease; LIHC trans rs1005277 0.579 rs1780130 chr10:38485378 T/A cg27523141 chr10:43048294 ZNF37B 0.39 6.57 0.33 1.92e-10 Extrinsic epigenetic age acceleration; LIHC cis rs4969178 0.600 rs2376583 chr17:76402105 A/T cg02836325 chr17:76403955 PGS1 0.31 6.08 0.31 3.3e-9 HDL cholesterol levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg02028489 chr16:31505237 C16orf58 0.41 6.42 0.33 4.59e-10 Longevity; LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg19500275 chr17:80737654 TBCD -0.51 -7.61 -0.38 2.63e-13 Glycated hemoglobin levels; LIHC cis rs4845459 0.967 rs6700290 chr1:152592978 T/A cg20634798 chr1:152595351 LCE3A -0.31 -6.03 -0.31 4.26e-9 Psoriasis; LIHC cis rs910316 0.737 rs175080 chr14:75513828 G/A cg08847533 chr14:75593920 NEK9 -0.9 -18.46 -0.71 2.88e-53 Height; LIHC trans rs1814175 0.645 rs7103554 chr11:50027612 G/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC trans rs12478296 0.591 rs4973646 chr2:243001373 C/T cg01596870 chr19:55963115 NA 0.66 10.03 0.48 6.53e-21 Obesity-related traits; LIHC cis rs2115630 0.577 rs7164817 chr15:85379544 T/C cg12501888 chr15:85177176 SCAND2 -0.42 -6.09 -0.31 3.1e-9 P wave terminal force; LIHC cis rs11055034 0.560 rs2024385 chr12:12888438 A/T cg09462578 chr12:12878428 APOLD1 0.63 10.82 0.5 1.18e-23 Birth weight; LIHC cis rs4953318 0.694 rs3768747 chr2:46352058 G/T cg12428440 chr2:46370979 PRKCE -0.39 -5.76 -0.3 1.91e-8 Red blood cell count;Hematocrit;Red blood cell traits; LIHC trans rs1814175 0.645 rs7115592 chr11:50013243 A/G cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs10791111 1 rs10791111 chr11:130856099 T/G cg12179176 chr11:130786555 SNX19 0.6 8.71 0.43 1.32e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs959260 1.000 rs959260 chr17:73369422 C/T cg20590849 chr17:73267439 MIF4GD -0.53 -5.75 -0.3 1.96e-8 Systemic lupus erythematosus; LIHC cis rs12602486 1.000 rs12602486 chr17:42241929 T/G cg13607699 chr17:42295918 UBTF -0.75 -6.42 -0.33 4.46e-10 Glycated hemoglobin levels; LIHC cis rs7212590 0.655 rs34687426 chr17:57997857 A/G cg10252138 chr17:58120427 NA -0.65 -6.92 -0.35 2.25e-11 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs2228479 0.702 rs12600151 chr16:89831558 C/T cg00800038 chr16:89945340 TCF25 -0.61 -8.97 -0.44 1.96e-17 Skin colour saturation; LIHC cis rs7903847 0.642 rs10882926 chr10:99160690 C/T cg08345082 chr10:99160200 RRP12 0.37 6.18 0.32 1.82e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6582630 0.533 rs4103689 chr12:38702980 A/C cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.42e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs6964587 1.000 rs28410528 chr7:91647390 A/G cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs9325144 0.560 rs7980358 chr12:38640396 C/G cg26384229 chr12:38710491 ALG10B 0.59 8.11 0.4 8.86e-15 Morning vs. evening chronotype; LIHC cis rs911119 0.657 rs6114214 chr20:23627924 A/T cg16589663 chr20:23618590 CST3 0.61 5.93 0.31 7.52e-9 Chronic kidney disease; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg10150615 chr22:24372951 LOC391322 -0.56 -8.09 -0.4 1.06e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6456156 0.716 rs6905911 chr6:167521624 C/T cg07741184 chr6:167504864 NA 0.25 6.02 0.31 4.61e-9 Primary biliary cholangitis; LIHC cis rs2295359 1.000 rs12043240 chr1:67624304 C/T cg12940439 chr1:67600707 NA 0.39 7.16 0.36 5.04e-12 Psoriasis; LIHC trans rs12478296 0.901 rs67423532 chr2:243004719 A/G cg01596870 chr19:55963115 NA -0.67 -9.61 -0.46 1.58e-19 Obesity-related traits; LIHC cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs2832191 0.791 rs2832202 chr21:30501342 G/A cg24692254 chr21:30365293 RNF160 -0.59 -10.27 -0.49 9.91e-22 Dental caries; LIHC cis rs12048904 0.541 rs1571046 chr1:101299216 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 9.79 0.47 4.03e-20 Multiple sclerosis; LIHC cis rs7659604 0.539 rs3217753 chr4:122746325 A/G cg19748678 chr4:122722346 EXOSC9 0.65 10.87 0.51 7.9e-24 Type 2 diabetes; LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg13409248 chr3:40428643 ENTPD3 0.47 7.75 0.39 1.09e-13 Renal cell carcinoma; LIHC trans rs7395555 0.848 rs4944251 chr11:80076944 G/A cg06295071 chr21:33766731 URB1 -0.42 -6.08 -0.31 3.19e-9 Response to antipsychotic treatment; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC trans rs11098499 0.863 rs3822194 chr4:120471648 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.45 0.46 5.34e-19 Corneal astigmatism; LIHC cis rs6088580 0.634 rs2378133 chr20:32919505 C/G cg08999081 chr20:33150536 PIGU -0.65 -12.63 -0.56 2.85e-30 Glomerular filtration rate (creatinine); LIHC cis rs922107 0.846 rs359922 chr1:89994577 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.42 -0.37 9.38e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg13259811 chr8:22550831 EGR3 -0.57 -6.47 -0.33 3.33e-10 Preeclampsia; LIHC trans rs2235573 0.551 rs84770 chr22:38390128 T/G cg19894588 chr14:64061835 NA 0.47 6.19 0.32 1.74e-9 Glioblastoma;Glioma; LIHC cis rs7789940 0.857 rs12532935 chr7:75939698 G/C cg10167463 chr7:75959203 YWHAG -0.44 -6.78 -0.34 5.27e-11 Multiple sclerosis; LIHC cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg12310025 chr6:25882481 NA -0.64 -9.08 -0.44 8.7e-18 Blood metabolite levels; LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg00656387 chr3:40428638 ENTPD3 0.5 8.33 0.41 1.91e-15 Renal cell carcinoma; LIHC cis rs1499280 1.000 rs6879147 chr5:52087852 T/G cg21153758 chr5:52083992 ITGA1;PELO -0.71 -6.56 -0.33 1.99e-10 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs483180 0.531 rs541503 chr1:120208297 A/G cg19096424 chr1:120255104 PHGDH -0.61 -7.41 -0.37 1.02e-12 Macular telangiectasia type 2; LIHC cis rs9513627 0.748 rs61525545 chr13:100118261 T/C cg25919922 chr13:100150906 NA -0.78 -7.02 -0.35 1.19e-11 Obesity-related traits; LIHC cis rs6570726 0.791 rs6912079 chr6:145894949 G/A cg13319975 chr6:146136371 FBXO30 -0.42 -6.84 -0.35 3.65e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7572733 0.534 rs696817 chr2:198722225 A/G cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg06601766 chr17:61851465 DDX42;CCDC47 -0.54 -8.43 -0.41 9.99e-16 Height; LIHC cis rs4908760 0.965 rs7542312 chr1:8573471 G/C cg20416874 chr1:8611966 RERE -0.67 -14.21 -0.61 2.4e-36 Vitiligo; LIHC cis rs748404 0.586 rs2584700 chr15:43685332 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.32 0.41 2.05e-15 Lung cancer; LIHC cis rs10256972 0.967 rs7799110 chr7:1039065 A/G cg07092213 chr7:1199455 ZFAND2A -0.38 -5.75 -0.3 2.03e-8 Longevity;Endometriosis; LIHC cis rs9640161 0.830 rs3757423 chr7:150067714 A/G cg17279839 chr7:150038598 RARRES2 -0.37 -7.36 -0.37 1.36e-12 Blood protein levels;Circulating chemerin levels; LIHC cis rs6750047 0.515 rs13417487 chr2:38289162 G/T cg07380506 chr2:38303506 CYP1B1 0.65 7.99 0.4 2.15e-14 Cutaneous malignant melanoma;Melanoma; LIHC cis rs9399135 0.967 rs13199205 chr6:135286505 T/C cg22676075 chr6:135203613 NA 0.38 6.25 0.32 1.26e-9 Red blood cell count; LIHC cis rs8044995 0.706 rs73612697 chr16:68162016 G/A cg05110241 chr16:68378359 PRMT7 -0.63 -7.06 -0.36 9.6e-12 Schizophrenia; LIHC cis rs7927771 0.524 rs7114813 chr11:47801101 A/G cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg26818010 chr10:134567672 INPP5A -0.79 -9.66 -0.46 1.12e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4319547 0.656 rs10734918 chr12:122921512 A/C cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.56 -0.38 3.81e-13 Body mass index; LIHC cis rs2404602 0.647 rs12904149 chr15:77043652 A/C cg23625390 chr15:77176239 SCAPER -0.54 -8.98 -0.44 1.81e-17 Blood metabolite levels; LIHC trans rs11722228 0.508 rs3822246 chr4:10094698 G/A cg26043149 chr18:55253948 FECH 0.97 14.03 0.6 1.24e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs798554 0.797 rs798486 chr7:2803037 A/G cg19717773 chr7:2847554 GNA12 -0.41 -6.63 -0.34 1.28e-10 Height; LIHC cis rs924607 0.510 rs1709542 chr5:662543 A/G cg04476341 chr5:669733 TPPP 0.28 6.13 0.31 2.36e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1448094 0.511 rs10506918 chr12:86227913 A/G cg02569458 chr12:86230093 RASSF9 -0.45 -6.12 -0.31 2.51e-9 Major depressive disorder; LIHC cis rs801193 1.000 rs13239306 chr7:66136017 T/G cg18876405 chr7:65276391 NA -0.41 -7.15 -0.36 5.42e-12 Aortic root size; LIHC cis rs9902453 0.817 rs55758314 chr17:28173978 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.32 0.55 4.05e-29 Coffee consumption (cups per day); LIHC cis rs6065325 0.514 rs55715261 chr20:40109855 C/T cg06610464 chr20:40243608 CHD6 0.38 6.14 0.32 2.28e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs921968 0.608 rs495855 chr2:219357858 A/G cg18887096 chr2:219472410 PLCD4 0.37 6.41 0.33 4.77e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg13770153 chr20:60521292 NA -0.33 -6.36 -0.33 6.45e-10 Body mass index; LIHC cis rs34779708 0.931 rs4934693 chr10:35271844 G/A cg03585969 chr10:35415529 CREM 0.86 13.01 0.58 9.87e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.5 0.77 1.88e-69 Height; LIHC cis rs1005277 0.579 rs176886 chr10:38403974 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.77 13.05 0.58 7.15e-32 Prudent dietary pattern; LIHC cis rs7917772 0.503 rs7078435 chr10:104304766 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.62 0.56 3.04e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs477692 0.905 rs7905466 chr10:131438937 A/T cg19680672 chr10:131412579 MGMT 0.41 6.31 0.32 8.74e-10 Response to temozolomide; LIHC cis rs651907 0.535 rs4342086 chr3:101503765 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.08 0.48 4.35e-21 Colorectal cancer; LIHC cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg02359409 chr6:42947317 PEX6 -0.49 -6.44 -0.33 4.03e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg15691649 chr6:25882328 NA -0.54 -7.82 -0.39 6.76e-14 Blood metabolite levels; LIHC trans rs2243480 1.000 rs160652 chr7:65538431 A/G cg10756647 chr7:56101905 PSPH 1.04 12.56 0.56 5.14e-30 Diabetic kidney disease; LIHC cis rs249954 0.559 rs35586 chr16:23677006 A/G cg05131483 chr16:23706242 ERN2 0.39 6.3 0.32 9.01e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2075371 0.829 rs35897242 chr7:134004041 G/A cg20476274 chr7:133979776 SLC35B4 0.67 9.25 0.45 2.43e-18 Mean platelet volume; LIHC cis rs754466 0.651 rs7895188 chr10:79623378 C/G cg17075019 chr10:79541650 NA 0.74 11.5 0.53 4.22e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2836974 0.644 rs11088471 chr21:40699313 A/G cg06238570 chr21:40685208 BRWD1 -0.52 -8.6 -0.42 2.91e-16 Cognitive function; LIHC cis rs12620999 1.000 rs4377286 chr2:238069686 C/T cg23555395 chr2:238036564 NA -0.32 -6.09 -0.31 3.02e-9 Systemic lupus erythematosus; LIHC cis rs950169 0.580 rs11633762 chr15:85187152 T/C cg12863693 chr15:85201151 NMB 0.45 6.23 0.32 1.36e-9 Schizophrenia; LIHC cis rs11690935 0.589 rs62183782 chr2:172865009 T/A cg13550731 chr2:172543902 DYNC1I2 0.45 6.78 0.34 5.25e-11 Schizophrenia; LIHC cis rs6684514 0.506 rs3762281 chr1:156304782 A/G cg08469215 chr1:156261351 TMEM79 0.36 6.15 0.32 2.19e-9 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg18357526 chr6:26021779 HIST1H4A -1.03 -15.87 -0.65 6.99e-43 Intelligence (multi-trait analysis); LIHC cis rs4665809 1.000 rs4665298 chr2:26256378 G/A cg04944784 chr2:26401820 FAM59B -0.67 -8.52 -0.42 5.08e-16 Gut microbiome composition (summer); LIHC cis rs7568458 0.709 rs2043675 chr2:85769975 C/T cg02493740 chr2:85810744 VAMP5 0.48 7.94 0.39 3.03e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.01e-19 Renal cell carcinoma; LIHC cis rs7940866 0.834 rs10791108 chr11:130849354 T/A cg12179176 chr11:130786555 SNX19 0.62 8.92 0.43 2.9e-17 Schizophrenia; LIHC cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg05564831 chr3:52568323 NT5DC2 0.37 6.0 0.31 5.11e-9 Electroencephalogram traits; LIHC cis rs796364 0.755 rs203762 chr2:200905136 C/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs7116495 0.529 rs575871 chr11:71778822 A/G cg26138937 chr11:71823887 C11orf51 -1.01 -8.93 -0.43 2.69e-17 Severe influenza A (H1N1) infection; LIHC cis rs2832191 0.740 rs2012645 chr21:30445961 G/A cg08807101 chr21:30365312 RNF160 0.78 11.71 0.54 7.24e-27 Dental caries; LIHC cis rs9457247 0.663 rs2282861 chr6:167440128 C/T cg12798992 chr6:167411361 FGFR1OP 0.53 8.75 0.43 9.73e-17 Crohn's disease; LIHC cis rs77633900 0.772 rs284884 chr15:76828289 A/G cg21673338 chr15:77095150 SCAPER -0.53 -5.92 -0.3 7.98e-9 Non-glioblastoma glioma;Glioma; LIHC trans rs8002861 0.905 rs9525869 chr13:44467210 A/G cg17145862 chr1:211918768 LPGAT1 0.67 13.3 0.58 8.19e-33 Leprosy; LIHC cis rs7927771 0.864 rs755553 chr11:47432303 G/A cg20307385 chr11:47447363 PSMC3 0.51 6.77 0.34 5.75e-11 Subjective well-being; LIHC cis rs6912958 0.500 rs4707352 chr6:87929705 G/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.35 -6.85 -0.35 3.51e-11 Monocyte percentage of white cells; LIHC cis rs7487075 0.619 rs7959731 chr12:46839657 A/C cg23829395 chr12:46796953 NA -0.34 -6.05 -0.31 3.78e-9 Itch intensity from mosquito bite; LIHC cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg11890956 chr21:40555474 PSMG1 1.07 16.04 0.66 1.47e-43 Cognitive function; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg04639062 chr2:21265939 APOB 0.44 7.25 0.36 2.88e-12 Calcium levels; LIHC cis rs922107 0.934 rs6700967 chr1:90017273 C/G cg15422784 chr1:90023713 LRRC8B -0.49 -7.9 -0.39 3.96e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs1008375 0.966 rs1860599 chr4:17638900 T/C cg02297831 chr4:17616191 MED28 0.5 7.93 0.39 3.05e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2257205 0.667 rs6503876 chr17:56814988 G/C cg12560992 chr17:57184187 TRIM37 0.71 7.81 0.39 7.13e-14 Pancreatic cancer; LIHC trans rs7558233 0.614 rs4665214 chr2:23678795 A/G cg02174006 chr10:86088279 FAM190B 0.45 6.04 0.31 3.95e-9 Cannabis use (initiation); LIHC cis rs17826219 0.568 rs59858012 chr17:29078582 C/T cg13385521 chr17:29058706 SUZ12P 0.83 7.68 0.38 1.7e-13 Body mass index; LIHC cis rs9768139 0.611 rs12698211 chr7:158119623 G/A cg25566285 chr7:158114605 PTPRN2 0.23 6.18 0.32 1.85e-9 Calcium levels; LIHC cis rs2749592 0.513 rs9417249 chr10:37837155 C/T cg25427524 chr10:38739819 LOC399744 0.45 7.75 0.39 1.05e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs35110281 0.591 rs162366 chr21:44935383 C/T cg21573476 chr21:45109991 RRP1B 0.47 8.6 0.42 2.87e-16 Mean corpuscular volume; LIHC cis rs916888 0.773 rs169201 chr17:44790203 A/G cg01570182 chr17:44337453 NA 1.01 10.04 0.48 5.84e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7197653 0.667 rs16957831 chr16:68378341 C/T cg05110241 chr16:68378359 PRMT7 -0.86 -9.84 -0.47 2.8e-20 Magnesium levels; LIHC cis rs9549367 0.826 rs2302755 chr13:113898418 C/T cg18105134 chr13:113819100 PROZ -0.58 -10.37 -0.49 4.26e-22 Platelet distribution width; LIHC cis rs2549003 0.966 rs2706386 chr5:131832687 C/T cg02551604 chr5:131831745 NA 0.47 7.23 0.36 3.18e-12 Asthma (sex interaction); LIHC cis rs10911251 0.528 rs4652779 chr1:183104552 G/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.16 0.48 2.21e-21 Colorectal cancer; LIHC trans rs637571 0.522 rs606978 chr11:65711517 A/C cg17712092 chr4:129076599 LARP1B 0.74 12.92 0.57 2.19e-31 Eosinophil percentage of white cells; LIHC cis rs2439831 0.681 rs528517 chr15:43612925 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.9 17.04 0.68 1.44e-47 Lung cancer in ever smokers; LIHC cis rs2243480 1.000 rs13237037 chr7:65997882 T/C cg18252515 chr7:66147081 NA -1.33 -18.17 -0.7 3.94e-52 Diabetic kidney disease; LIHC cis rs2576037 0.501 rs7245049 chr18:44528213 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.13 -0.36 5.99e-12 Personality dimensions; LIHC cis rs7772486 0.790 rs9403750 chr6:146167762 G/A cg05347473 chr6:146136440 FBXO30 0.35 5.82 0.3 1.35e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs12220238 1.000 rs3812638 chr10:75896072 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.7 6.77 0.34 5.49e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs644799 0.526 rs542509 chr11:95641602 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.6 9.46 0.46 5.03e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg19635926 chr16:89946313 TCF25 0.51 7.13 0.36 5.91e-12 Skin colour saturation; LIHC cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg12463550 chr7:65579703 CRCP 0.69 7.2 0.36 3.93e-12 Diabetic kidney disease; LIHC cis rs727505 1.000 rs10464529 chr7:124520308 G/A cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.1e-9 Lewy body disease; LIHC cis rs651907 0.557 rs3094297 chr3:101399260 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 13.09 0.58 5.2e-32 Colorectal cancer; LIHC cis rs6960043 0.818 rs10264063 chr7:15053193 G/C cg19272540 chr7:15055459 NA 0.25 6.87 0.35 3.08e-11 Type 2 diabetes; LIHC cis rs10489202 0.608 rs7556350 chr1:168077797 C/T cg24449463 chr1:168025552 DCAF6 -0.44 -6.22 -0.32 1.47e-9 Schizophrenia; LIHC cis rs929354 0.742 rs10251112 chr7:156963524 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.95 -0.31 6.62e-9 Body mass index; LIHC cis rs11190604 1.000 rs2489046 chr10:102346282 A/C cg07080220 chr10:102295463 HIF1AN 0.53 7.66 0.38 1.9e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2257205 0.667 rs7217890 chr17:56731265 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs174601 0.861 rs174547 chr11:61570783 C/T cg07689907 chr11:61582574 FADS1 -0.41 -6.06 -0.31 3.57e-9 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14634319 chr12:57030450 BAZ2A 0.45 6.07 0.31 3.41e-9 Pancreatic cancer; LIHC cis rs11822910 0.737 rs2581924 chr11:57208468 C/T cg00522883 chr11:57194120 SLC43A3 0.56 6.96 0.35 1.7e-11 Platelet distribution width; LIHC trans rs4927850 0.958 rs1975582 chr3:195751439 G/T cg21051086 chr3:73046214 PPP4R2 -0.38 -6.16 -0.32 2.07e-9 Pancreatic cancer; LIHC cis rs3736485 0.934 rs4775953 chr15:51873173 G/T cg08986416 chr15:51914746 DMXL2 -0.43 -6.4 -0.33 5.14e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs941873 0.868 rs7332 chr10:81114060 G/A cg09469691 chr10:81107165 PPIF 0.69 10.52 0.49 1.27e-22 Height; LIHC cis rs2963155 0.518 rs6196 chr5:142661490 A/G cg17617527 chr5:142782415 NR3C1 0.91 10.58 0.5 8.3e-23 Breast cancer; LIHC cis rs3106136 0.527 rs10030586 chr4:95150805 A/C cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.03 -0.44 1.31e-17 Capecitabine sensitivity; LIHC cis rs3806843 0.766 rs702397 chr5:140050265 A/G cg19875535 chr5:140030758 IK -0.39 -6.31 -0.32 8.75e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6121246 0.954 rs6121245 chr20:30432060 G/A cg13852791 chr20:30311386 BCL2L1 0.84 8.92 0.43 2.9e-17 Mean corpuscular hemoglobin; LIHC trans rs216345 1.000 rs216345 chr9:33799370 C/T cg14607208 chr9:38546089 NA 0.4 6.2 0.32 1.58e-9 Bipolar disorder; LIHC cis rs60871478 1.000 rs62432899 chr7:826542 G/C cg00934597 chr7:893267 UNC84A 0.48 5.79 0.3 1.57e-8 Cerebrospinal P-tau181p levels; LIHC cis rs6500602 0.592 rs4785966 chr16:4518754 C/T cg08645402 chr16:4508243 NA -0.4 -7.38 -0.37 1.2e-12 Schizophrenia; LIHC cis rs7589728 0.514 rs74426843 chr2:88459388 C/T cg04511125 chr2:88470314 THNSL2 0.97 9.88 0.47 1.97e-20 Plasma clusterin levels; LIHC cis rs4819052 0.788 rs4819051 chr21:46693128 C/T cg22633049 chr21:46681294 NA -0.38 -6.41 -0.33 4.75e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3936840 0.861 rs1044502 chr14:102965897 G/A cg18135206 chr14:102964638 TECPR2 0.41 5.98 0.31 5.52e-9 Plateletcrit; LIHC cis rs7044106 0.762 rs4142158 chr9:123410819 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.83 0.39 6.05e-14 Hip circumference adjusted for BMI; LIHC cis rs2842992 0.692 rs9347342 chr6:160193129 T/C cg16489826 chr6:160211363 TCP1;MRPL18 0.49 9.09 0.44 8.28e-18 Age-related macular degeneration (geographic atrophy); LIHC trans rs1814175 0.817 rs12287396 chr11:49819798 G/C cg15704280 chr7:45808275 SEPT13 -1.03 -23.92 -0.79 5.08e-75 Height; LIHC cis rs1190552 0.846 rs12883789 chr14:102954621 G/A cg10241871 chr14:102965420 TECPR2 -0.48 -7.57 -0.38 3.47e-13 Blood protein levels; LIHC trans rs9929218 0.954 rs57688464 chr16:68826109 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.58 -0.42 3.44e-16 Colorectal cancer; LIHC cis rs11711311 1.000 rs2566970 chr3:113462123 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.38 7.01 0.35 1.27e-11 IgG glycosylation; LIHC trans rs4906332 1.000 rs35366629 chr14:103903054 A/G cg17675199 chr6:35436792 RPL10A 0.34 6.65 0.34 1.17e-10 Coronary artery disease; LIHC cis rs9303401 0.555 rs8073699 chr17:57236317 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.42 6.14 0.32 2.25e-9 Cognitive test performance; LIHC cis rs6545883 0.894 rs2694643 chr2:61604383 A/G cg14146966 chr2:61757674 XPO1 0.44 7.31 0.37 1.96e-12 Tuberculosis; LIHC cis rs1552244 0.882 rs13088350 chr3:10044626 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg18357526 chr6:26021779 HIST1H4A 0.91 13.57 0.59 7.7e-34 Intelligence (multi-trait analysis); LIHC cis rs9560113 1.000 rs9560106 chr13:112179605 A/G cg14154082 chr13:112174009 NA 0.28 5.98 0.31 5.48e-9 Menarche (age at onset); LIHC cis rs7615952 0.576 rs6804482 chr3:125815762 C/T cg05084668 chr3:125655381 ALG1L -0.38 -5.92 -0.3 7.91e-9 Blood pressure (smoking interaction); LIHC cis rs7618501 0.633 rs2856234 chr3:50139142 A/G cg21467203 chr3:49911342 NA 0.44 7.81 0.39 7.1e-14 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.44 0.37 8.24e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7539409 0.651 rs969724 chr1:84300712 T/G cg10977910 chr1:84465055 TTLL7 0.71 7.18 0.36 4.38e-12 Alzheimer's disease; LIHC cis rs7615952 1.000 rs7616044 chr3:125649354 G/C cg05084668 chr3:125655381 ALG1L -0.56 -8.07 -0.4 1.18e-14 Blood pressure (smoking interaction); LIHC cis rs1005277 0.579 rs2504148 chr10:38400788 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs916888 0.773 rs199439 chr17:44793503 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.74 6.99 0.35 1.49e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs17152411 0.625 rs10736892 chr10:126594892 G/A cg07906193 chr10:126599966 NA -0.3 -5.82 -0.3 1.32e-8 Height; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg03383472 chr7:2314947 SNX8 0.49 6.67 0.34 1.01e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs5769765 0.955 rs8135963 chr22:50301476 T/C cg02269571 chr22:50332266 NA -0.62 -8.78 -0.43 7.76e-17 Schizophrenia; LIHC cis rs34779708 0.966 rs12769484 chr10:35465746 G/A cg03585969 chr10:35415529 CREM 0.87 13.14 0.58 3.25e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2204008 0.837 rs10876019 chr12:37985477 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.73 0.5 2.39e-23 Bladder cancer; LIHC cis rs9473924 0.505 rs7745565 chr6:50860083 A/G cg14470998 chr6:50812995 TFAP2B 0.93 10.83 0.51 1.08e-23 Body mass index; LIHC cis rs2933343 1.000 rs876755 chr3:128627933 C/T cg25356066 chr3:128598488 ACAD9 0.53 7.0 0.35 1.39e-11 IgG glycosylation; LIHC cis rs9486719 1.000 rs6923212 chr6:97061940 A/G cg06623918 chr6:96969491 KIAA0776 -0.75 -7.69 -0.38 1.6e-13 Migraine;Coronary artery disease; LIHC cis rs4742903 0.875 rs10820609 chr9:106907332 G/A cg14250997 chr9:106856677 SMC2 0.37 6.61 0.34 1.48e-10 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6570726 0.791 rs379040 chr6:145889035 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.98 -0.31 5.7e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04207741 chr12:57482553 NAB2 0.46 6.09 0.31 3.03e-9 Lung function (FEV1/FVC); LIHC cis rs6860806 0.507 rs272882 chr5:131669161 G/T cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.82e-31 Breast cancer; LIHC cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg05564831 chr3:52568323 NT5DC2 0.35 5.83 0.3 1.27e-8 Bipolar disorder; LIHC cis rs1552244 0.608 rs6764807 chr3:9998803 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -7.77 -0.39 9.19e-14 Alzheimer's disease; LIHC cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg09222892 chr1:25734099 RHCE -0.47 -8.55 -0.42 4.28e-16 Erythrocyte sedimentation rate; LIHC cis rs1401999 0.659 rs4912518 chr3:183752027 C/T cg05044414 chr3:183734942 ABCC5 -0.35 -5.91 -0.3 8.48e-9 Anterior chamber depth; LIHC cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.24 -0.32 1.26e-9 Bipolar disorder and schizophrenia; LIHC cis rs12464559 0.649 rs4453694 chr2:152539550 T/C cg01189475 chr2:152685088 ARL5A 0.66 7.82 0.39 6.42e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs4474465 0.790 rs10899541 chr11:78245573 A/G cg27205649 chr11:78285834 NARS2 -0.41 -6.37 -0.33 6.26e-10 Alzheimer's disease (survival time); LIHC cis rs6748734 1.000 rs7604393 chr2:241825034 T/G cg09990169 chr2:241835740 C2orf54 -0.64 -9.07 -0.44 9.5e-18 Urinary metabolites; LIHC cis rs2463822 0.748 rs2513053 chr11:62109473 T/A cg06239285 chr11:62104954 ASRGL1 0.93 7.04 0.36 1.04e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs12478296 0.681 rs55802421 chr2:243033962 C/T cg06360820 chr2:242988706 NA -0.82 -11.43 -0.53 7.73e-26 Obesity-related traits; LIHC cis rs926392 0.572 rs6129156 chr20:37672209 A/C cg16355469 chr20:37678765 NA 0.48 7.85 0.39 5.43e-14 Dialysis-related mortality; LIHC cis rs11786130 1.000 rs4733812 chr8:128999640 C/T cg01765152 chr8:129005526 PVT1 -0.31 -6.97 -0.35 1.6e-11 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs2304069 1.000 rs10072275 chr5:149401596 T/C cg12661370 chr5:149340060 SLC26A2 0.48 5.8 0.3 1.49e-8 HIV-1 control; LIHC cis rs881375 0.900 rs1930786 chr9:123691469 C/G cg14580859 chr9:123691850 NA 0.4 7.0 0.35 1.39e-11 Rheumatoid arthritis; LIHC cis rs1144333 0.655 rs76735776 chr1:76455211 A/G cg22875332 chr1:76189707 ACADM 0.4 5.93 0.31 7.24e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg07167872 chr1:205819463 PM20D1 0.6 8.79 0.43 7.43e-17 Menarche (age at onset); LIHC cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg24549020 chr5:56110836 MAP3K1 0.49 6.29 0.32 9.61e-10 Initial pursuit acceleration; LIHC cis rs4631830 0.600 rs11004324 chr10:51496623 G/T cg20129853 chr10:51489980 NA -0.44 -8.78 -0.43 7.79e-17 Prostate-specific antigen levels; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg26338869 chr17:61819248 STRADA 0.58 8.33 0.41 1.98e-15 Prudent dietary pattern; LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg07677032 chr17:61819896 STRADA 0.42 6.11 0.31 2.72e-9 Prudent dietary pattern; LIHC cis rs6445967 0.689 rs11714574 chr3:58380465 A/T cg23715586 chr3:58305044 RPP14 0.38 6.31 0.32 8.85e-10 Platelet count; LIHC cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.48 6.86 0.35 3.23e-11 Height; LIHC cis rs16858210 0.607 rs35205152 chr3:183563329 C/A cg25686905 chr3:183603175 PARL -0.51 -8.76 -0.43 8.95e-17 Menopause (age at onset); LIHC cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.26 0.52 3.09e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.51 0.56 7.86e-30 Prudent dietary pattern; LIHC cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg16606324 chr3:10149918 C3orf24 0.51 5.86 0.3 1.08e-8 Alzheimer's disease; LIHC cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg13409248 chr3:40428643 ENTPD3 0.46 7.43 0.37 8.67e-13 Renal cell carcinoma; LIHC cis rs2386661 0.603 rs11259704 chr10:5646999 C/T cg17085576 chr10:5658249 NA -0.32 -6.15 -0.32 2.2e-9 Breast cancer; LIHC cis rs9303401 0.614 rs28651036 chr17:57080471 G/A cg25039879 chr17:56429692 SUPT4H1 0.76 8.75 0.43 1.02e-16 Cognitive test performance; LIHC cis rs9660992 0.539 rs113699533 chr1:205122895 G/A cg21545522 chr1:205238299 TMCC2 0.3 5.74 0.3 2.08e-8 Mean corpuscular volume;Mean platelet volume; LIHC cis rs8081395 0.866 rs2777899 chr17:57832391 T/G cg13753209 chr17:57696993 CLTC -0.48 -7.3 -0.37 2.08e-12 White blood cell count; LIHC cis rs17685 0.753 rs6464999 chr7:75787315 T/C cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10744422 0.925 rs2880678 chr12:123317099 C/T cg07706471 chr12:123319906 HIP1R -0.56 -7.36 -0.37 1.37e-12 Schizophrenia; LIHC cis rs11864453 0.826 rs9941087 chr16:72118324 G/A cg16558253 chr16:72132732 DHX38 -0.49 -7.66 -0.38 1.95e-13 Fibrinogen levels; LIHC cis rs477895 0.713 rs11600867 chr11:63972052 T/A cg18225595 chr11:63971243 STIP1 0.67 8.32 0.41 2.14e-15 Mean platelet volume; LIHC cis rs6450176 1.000 rs58369491 chr5:53297295 T/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs9911578 0.967 rs2333410 chr17:57137129 G/A cg12560992 chr17:57184187 TRIM37 -0.97 -17.82 -0.69 1.03e-50 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.892 rs9379806 chr6:25940958 G/A cg12310025 chr6:25882481 NA -0.42 -6.34 -0.32 7.27e-10 Height; LIHC cis rs700651 0.789 rs10184395 chr2:198894285 G/A cg00792783 chr2:198669748 PLCL1 0.42 6.16 0.32 2.09e-9 Intracranial aneurysm; LIHC trans rs2727020 0.617 rs7102702 chr11:49401125 T/G cg03929089 chr4:120376271 NA -0.71 -11.02 -0.51 2.22e-24 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04358685 chr3:12598421 MKRN2 0.52 6.72 0.34 7.84e-11 Lung function (FEV1/FVC); LIHC cis rs7584330 0.554 rs3751105 chr2:238428459 G/A cg08992911 chr2:238395768 MLPH 0.52 6.34 0.32 7.29e-10 Prostate cancer; LIHC cis rs10744422 1.000 rs7959441 chr12:123363825 C/T cg22842854 chr12:123319900 HIP1R -0.6 -7.29 -0.37 2.2e-12 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06498398 chr8:11627480 NEIL2 0.49 6.91 0.35 2.36e-11 Pancreatic cancer; LIHC cis rs12586317 0.620 rs2295104 chr14:35579927 A/G cg16230307 chr14:35515116 FAM177A1 -0.82 -14.14 -0.61 4.66e-36 Psoriasis; LIHC cis rs8084351 0.577 rs4456578 chr18:50621094 A/G cg24270629 chr18:50823537 DCC 0.44 6.71 0.34 8.04e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7703051 0.513 rs6895057 chr5:74624234 G/A cg00601450 chr5:74908170 NA -0.48 -6.8 -0.35 4.56e-11 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs5753618 0.509 rs5753500 chr22:31578879 A/G cg07713946 chr22:31675144 LIMK2 -0.42 -7.43 -0.37 8.83e-13 Colorectal cancer; LIHC cis rs9583531 0.527 rs3818496 chr13:111358488 G/A cg24331049 chr13:111365604 ING1 0.63 10.72 0.5 2.51e-23 Coronary artery disease; LIHC cis rs929354 0.713 rs3802130 chr7:156965237 A/G cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs921968 0.541 rs1863704 chr2:219562675 C/T cg02176678 chr2:219576539 TTLL4 -0.52 -6.89 -0.35 2.77e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs67478160 0.643 rs2295145 chr14:104202304 G/A cg08213375 chr14:104286397 PPP1R13B 0.61 11.64 0.53 1.3e-26 Schizophrenia; LIHC cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg03517284 chr6:25882590 NA 0.58 8.47 0.42 7.55e-16 Blood metabolite levels; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg08804258 chr3:8543341 LMCD1 -0.42 -6.04 -0.31 4.03e-9 Alopecia areata; LIHC cis rs16854884 0.558 rs60367530 chr3:143719294 G/A cg06585982 chr3:143692056 C3orf58 0.47 5.79 0.3 1.57e-8 Economic and political preferences (feminism/equality); LIHC cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg20295408 chr7:1910781 MAD1L1 -0.52 -7.57 -0.38 3.41e-13 Bipolar disorder and schizophrenia; LIHC cis rs1475911 1.000 rs2839467 chr21:43513200 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 -0.76 -11.32 -0.52 1.86e-25 IgG glycosylation; LIHC cis rs763121 0.819 rs5757237 chr22:39073835 G/C cg06022373 chr22:39101656 GTPBP1 0.65 11.39 0.52 1.05e-25 Menopause (age at onset); LIHC cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg22974920 chr21:40686053 BRWD1 -0.39 -5.71 -0.3 2.44e-8 Cognitive function; LIHC cis rs2404602 0.647 rs907593 chr15:77196953 G/A cg23625390 chr15:77176239 SCAPER -0.51 -8.36 -0.41 1.62e-15 Blood metabolite levels; LIHC trans rs1499614 1.000 rs2707830 chr7:66167645 T/C cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs2404602 0.716 rs66754747 chr15:76828568 G/A cg03037974 chr15:76606532 NA 0.74 14.45 0.62 2.85e-37 Blood metabolite levels; LIHC cis rs4819052 1.000 rs733739 chr21:46666210 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 9.89 0.47 1.87e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10751667 0.714 rs7396700 chr11:963863 A/C ch.11.42038R chr11:967971 AP2A2 0.56 10.13 0.48 2.88e-21 Alzheimer's disease (late onset); LIHC cis rs6120849 0.663 rs6088662 chr20:33547633 A/C cg07148914 chr20:33460835 GGT7 0.54 6.11 0.31 2.66e-9 Protein C levels; LIHC cis rs9911578 1.000 rs302859 chr17:56693132 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs2834188 1.000 rs2834187 chr21:34687410 A/G cg14352951 chr21:34696688 IFNAR1 0.47 6.48 0.33 3.12e-10 Narcolepsy; LIHC cis rs9916302 0.706 rs4795358 chr17:37573065 A/C cg07936489 chr17:37558343 FBXL20 -0.85 -12.11 -0.55 2.54e-28 Glomerular filtration rate (creatinine); LIHC cis rs77633900 0.772 rs172244 chr15:76722769 A/T cg21673338 chr15:77095150 SCAPER -0.53 -5.92 -0.3 7.98e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs2361718 0.500 rs4889818 chr17:78085228 A/G cg09238746 chr17:78121135 EIF4A3 -0.79 -12.15 -0.55 1.76e-28 Yeast infection; LIHC cis rs7615952 0.575 rs35949599 chr3:125544202 G/A cg05084668 chr3:125655381 ALG1L -0.34 -6.13 -0.31 2.39e-9 Blood pressure (smoking interaction); LIHC cis rs116095464 0.558 rs28729548 chr5:229025 C/T cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC trans rs1814175 0.645 rs847635 chr11:49923323 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg14828511 chr1:107599125 PRMT6 -0.43 -6.16 -0.32 1.99e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg06212747 chr3:49208901 KLHDC8B 0.59 7.92 0.39 3.35e-14 Parkinson's disease; LIHC cis rs9611565 0.649 rs5758466 chr22:42176059 G/A cg06634786 chr22:41940651 POLR3H 0.55 5.82 0.3 1.33e-8 Vitiligo; LIHC cis rs8062405 0.755 rs17707300 chr16:28593347 A/G cg07451762 chr16:28383216 NA 0.4 7.03 0.36 1.13e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6684514 0.961 rs12126696 chr1:156241348 C/T cg16558208 chr1:156270281 VHLL 0.52 9.65 0.46 1.17e-19 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs11627756 0.846 rs12887440 chr14:103083899 G/A cg12046867 chr14:103022105 NA -0.38 -5.84 -0.3 1.21e-8 Mean platelet volume; LIHC cis rs116248771 0.739 rs78151625 chr3:158316726 T/C cg16708174 chr3:158430962 RARRES1 0.47 6.02 0.31 4.41e-9 diarrhoeal disease at age 2; LIHC cis rs7927771 0.965 rs12364432 chr11:47902883 G/A cg20307385 chr11:47447363 PSMC3 -0.46 -6.01 -0.31 4.67e-9 Subjective well-being; LIHC cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg24549020 chr5:56110836 MAP3K1 0.48 6.32 0.32 8.38e-10 Initial pursuit acceleration; LIHC cis rs801193 0.569 rs2707824 chr7:66189243 A/G cg18252515 chr7:66147081 NA -0.46 -6.78 -0.34 5.17e-11 Aortic root size; LIHC cis rs9549367 0.713 rs2146750 chr13:113822530 A/G cg18105134 chr13:113819100 PROZ 0.65 10.7 0.5 3.02e-23 Platelet distribution width; LIHC cis rs11718455 0.960 rs3843372 chr3:43997666 C/T cg08738300 chr3:44038990 NA 0.51 8.96 0.44 2.18e-17 Coronary artery disease; LIHC cis rs17106184 1.000 rs114736728 chr1:51374608 T/G cg07174182 chr1:51127561 FAF1 -0.75 -7.65 -0.38 2.01e-13 Type 2 diabetes; LIHC cis rs765787 0.505 rs11630884 chr15:45532246 C/T cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.76 -0.3 1.86e-8 Uric acid levels; LIHC cis rs796364 0.587 rs7588746 chr2:200986345 A/G cg23649088 chr2:200775458 C2orf69 0.46 6.08 0.31 3.28e-9 Schizophrenia; LIHC cis rs12464559 0.579 rs6433590 chr2:152588120 A/C cg01189475 chr2:152685088 ARL5A 0.67 7.78 0.39 8.52e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg05185784 chr16:90016020 DEF8 -0.5 -6.39 -0.33 5.56e-10 Skin colour saturation; LIHC cis rs11190604 1.000 rs2495750 chr10:102327708 A/G cg07080220 chr10:102295463 HIF1AN 0.54 7.29 0.37 2.16e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs7618501 1.000 rs7374183 chr3:49785133 G/A cg21659725 chr3:3221576 CRBN -0.99 -19.64 -0.73 4.88e-58 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg06640241 chr16:89574553 SPG7 0.8 14.65 0.62 4.68e-38 Multiple myeloma (IgH translocation); LIHC cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg18404041 chr3:52824283 ITIH1 -0.68 -11.14 -0.52 8.32e-25 Bipolar disorder; LIHC cis rs8060686 0.641 rs2285910 chr16:68104422 T/C cg05110241 chr16:68378359 PRMT7 -0.6 -7.05 -0.36 9.98e-12 HDL cholesterol;Metabolic syndrome; LIHC cis rs4423214 0.840 rs1792233 chr11:71182179 G/A cg05163923 chr11:71159392 DHCR7 -0.59 -7.8 -0.39 7.55e-14 Vitamin D levels; LIHC cis rs16866061 1.000 rs7588380 chr2:225341304 A/T cg12698349 chr2:225449008 CUL3 -0.72 -12.17 -0.55 1.53e-28 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs1577917 0.740 rs9450302 chr6:86289673 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.12 0.44 6.48e-18 Response to antipsychotic treatment; LIHC cis rs34779708 0.931 rs2384275 chr10:35297142 A/G cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.4e-27 Inflammatory bowel disease;Crohn's disease; LIHC trans rs1814175 0.566 rs1811673 chr11:49602134 A/G cg15704280 chr7:45808275 SEPT13 -0.8 -11.97 -0.54 8.41e-28 Height; LIHC cis rs10876993 0.890 rs12302351 chr12:58062590 T/C cg15848620 chr12:58087721 OS9 -0.53 -7.14 -0.36 5.69e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs9534288 0.843 rs2094245 chr13:46602207 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.32 -0.41 2.05e-15 Blood protein levels; LIHC cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.52 -0.56 7.42e-30 Alzheimer's disease; LIHC cis rs826838 1.000 rs7975243 chr12:38849220 C/T cg13010199 chr12:38710504 ALG10B 0.61 7.5 0.38 5.64e-13 Heart rate; LIHC trans rs11098499 0.908 rs7696649 chr4:120322177 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.58 0.46 2e-19 Corneal astigmatism; LIHC cis rs9420 0.961 rs7117205 chr11:57641883 A/G cg19752551 chr11:57585705 CTNND1 -0.48 -6.67 -0.34 1.06e-10 Schizophrenia; LIHC cis rs2204008 0.805 rs2874289 chr12:38258420 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs9486715 0.838 rs7770889 chr6:96858453 C/T cg06623918 chr6:96969491 KIAA0776 -0.71 -11.68 -0.53 9.81e-27 Headache; LIHC cis rs2304069 0.954 rs10068537 chr5:149403193 G/A cg12661370 chr5:149340060 SLC26A2 0.5 5.99 0.31 5.42e-9 HIV-1 control; LIHC cis rs61990749 0.597 rs8003691 chr14:78211225 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.63 10.53 0.49 1.23e-22 Fibroblast growth factor basic levels; LIHC cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg24101359 chr6:42928495 GNMT 0.45 5.99 0.31 5.26e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs28374715 0.662 rs111522288 chr15:41480169 C/T cg18705301 chr15:41695430 NDUFAF1 -0.85 -9.54 -0.46 2.73e-19 Ulcerative colitis; LIHC cis rs2072499 0.778 rs2247476 chr1:156190280 C/A cg25208724 chr1:156163844 SLC25A44 0.69 7.55 0.38 4.03e-13 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs1335628 chr6:8491742 A/T cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs7131987 0.845 rs2042511 chr12:29408780 C/T cg21522988 chr12:29376872 FAR2 0.28 6.42 0.33 4.61e-10 QT interval; LIHC cis rs950169 0.845 rs4106951 chr15:84833394 C/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.81 0.43 6.38e-17 Schizophrenia; LIHC cis rs5753618 0.509 rs5997913 chr22:31593959 C/A cg22777020 chr22:31556080 RNF185 -0.55 -6.26 -0.32 1.15e-9 Colorectal cancer; LIHC cis rs5769765 0.542 rs5770720 chr22:50253101 A/G cg02269571 chr22:50332266 NA 0.7 8.05 0.4 1.38e-14 Schizophrenia; LIHC cis rs12744310 1.000 rs60552457 chr1:41759499 C/A cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.72e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs17539620 0.624 rs111484697 chr6:154838903 A/G cg20019720 chr6:154832845 CNKSR3 0.4 6.06 0.31 3.63e-9 Lipoprotein (a) levels; LIHC trans rs8073060 0.544 rs2626626 chr17:34026717 A/G cg19694781 chr19:47549865 TMEM160 -1.22 -13.08 -0.58 5.37e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9549367 0.713 rs4907598 chr13:113861385 C/T cg00898013 chr13:113819073 PROZ 0.35 6.21 0.32 1.51e-9 Platelet distribution width; LIHC cis rs6750047 0.546 rs1367696 chr2:38286914 C/T cg07380506 chr2:38303506 CYP1B1 0.61 7.78 0.39 8.39e-14 Cutaneous malignant melanoma;Melanoma; LIHC cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg13866156 chr1:1669148 SLC35E2 -0.71 -13.64 -0.59 4.1e-34 Body mass index; LIHC cis rs1863824 0.625 rs10887599 chr10:88168780 G/A cg07322936 chr10:88137208 NA -0.47 -5.99 -0.31 5.43e-9 Schizophrenia; LIHC cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.3 -6.01 -0.31 4.86e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs4555082 0.834 rs2816652 chr14:105712493 C/T cg10792982 chr14:105748885 BRF1 0.48 6.3 0.32 9.36e-10 Mean platelet volume;Platelet distribution width; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg21718627 chr11:87035156 TMEM135 -0.26 -6.26 -0.32 1.14e-9 Calcium levels; LIHC cis rs9902453 0.933 rs7216494 chr17:28502651 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.05 0.44 1.07e-17 Coffee consumption (cups per day); LIHC trans rs11638815 0.626 rs11633829 chr15:83326938 C/T cg18393722 chr15:85113863 UBE2QP1 0.37 6.08 0.31 3.13e-9 Lipoprotein-associated phospholipase A2 activity change in response to statin therapy; LIHC cis rs769267 0.965 rs735273 chr19:19385411 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs4332037 0.950 rs7807014 chr7:1939021 T/C cg23422044 chr7:1970798 MAD1L1 -0.64 -7.33 -0.37 1.67e-12 Bipolar disorder; LIHC cis rs477895 0.713 rs7952318 chr11:63961242 G/A cg05555928 chr11:63887634 MACROD1 0.44 5.73 0.3 2.15e-8 Mean platelet volume; LIHC cis rs4665809 1.000 rs10048683 chr2:26320519 C/T cg04944784 chr2:26401820 FAM59B -0.65 -8.29 -0.41 2.58e-15 Gut microbiome composition (summer); LIHC cis rs2191566 0.664 rs7250774 chr19:44551867 A/T cg20607764 chr19:44506953 ZNF230 -0.37 -6.25 -0.32 1.21e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs4073582 0.595 rs801736 chr11:65928430 A/T cg14036092 chr11:66035641 RAB1B 0.4 5.97 0.31 6.01e-9 Gout; LIHC cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg05368731 chr17:41323189 NBR1 0.72 12.34 0.55 3.56e-29 Menopause (age at onset); LIHC cis rs1707322 0.685 rs11211177 chr1:46226349 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.07 0.36 8.98e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1046896 1.000 rs28485881 chr17:80690014 G/A cg00809820 chr17:80708513 TBCD;FN3K 0.34 5.87 0.3 1.01e-8 Glycated hemoglobin levels; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs3020736 0.500 rs4147641 chr22:42482502 C/G cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs12586317 0.547 rs45531432 chr14:35484423 C/T cg16230307 chr14:35515116 FAM177A1 0.79 13.35 0.59 5.37e-33 Psoriasis; LIHC trans rs1961637 0.603 rs1550423 chr2:223885812 C/T cg11372090 chr7:37488660 ELMO1 -0.38 -6.22 -0.32 1.45e-9 Oropharynx cancer; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.48 0.62 2.23e-37 Prudent dietary pattern; LIHC cis rs2836950 0.520 rs59916147 chr21:40634702 T/G cg06238570 chr21:40685208 BRWD1 -0.45 -7.21 -0.36 3.63e-12 Menarche (age at onset); LIHC cis rs713477 0.712 rs72717779 chr14:55893440 A/G cg13175173 chr14:55914753 NA -0.31 -7.15 -0.36 5.45e-12 Pediatric bone mineral content (femoral neck); LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.85 -0.3 1.14e-8 Total body bone mineral density; LIHC cis rs9486719 1.000 rs3798295 chr6:97052164 C/T cg06623918 chr6:96969491 KIAA0776 -0.68 -6.63 -0.34 1.27e-10 Migraine;Coronary artery disease; LIHC trans rs877282 1.000 rs10904552 chr10:774326 A/G cg22713356 chr15:30763199 NA 1.12 10.23 0.48 1.36e-21 Uric acid levels; LIHC cis rs7412746 0.658 rs12067685 chr1:150952917 T/C cg18016565 chr1:150552671 MCL1 0.52 9.64 0.46 1.29e-19 Melanoma; LIHC cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg15691649 chr6:25882328 NA -0.54 -7.75 -0.39 1.07e-13 Blood metabolite levels; LIHC cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg20090690 chr10:134436459 INPP5A 0.44 5.76 0.3 1.86e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs72960926 0.744 rs1931272 chr6:74950681 C/T cg07247405 chr1:2484626 LOC115110 0.53 6.38 0.33 5.78e-10 Metabolite levels (MHPG); LIHC cis rs716804 0.740 rs12290748 chr11:10262206 G/A cg01453529 chr11:10209919 SBF2 -0.29 -5.78 -0.3 1.67e-8 Neuroticism; LIHC cis rs2836950 0.501 rs62223052 chr21:40708702 A/C cg11890956 chr21:40555474 PSMG1 -0.44 -6.97 -0.35 1.64e-11 Menarche (age at onset); LIHC cis rs9368481 0.761 rs4713062 chr6:26948195 A/G cg12292205 chr6:26970375 C6orf41 -0.48 -8.15 -0.4 6.75e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs10752881 1.000 rs4304541 chr1:182970238 G/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.36 0.49 4.72e-22 Colorectal cancer; LIHC cis rs2242116 1.000 rs2168443 chr3:46947087 A/T cg02527881 chr3:46936655 PTH1R 0.46 9.63 0.46 1.39e-19 Birth weight; LIHC cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs8084351 0.539 rs8085965 chr18:50561632 G/T cg24270629 chr18:50823537 DCC 0.4 5.91 0.3 8.17e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs6788895 0.661 rs1533711 chr3:150469996 C/T cg09723797 chr3:150481914 SIAH2 -0.81 -11.88 -0.54 1.75e-27 Breast cancer; LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs12594515 1.000 rs6493168 chr15:45986811 A/C cg01629716 chr15:45996671 NA 0.52 9.65 0.46 1.25e-19 Waist circumference;Weight; LIHC cis rs9309473 1.000 rs6546838 chr2:73679280 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.83 -0.35 3.84e-11 Metabolite levels; LIHC trans rs208515 0.592 rs10944862 chr6:66674215 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.99 0.44 1.65e-17 Exhaled nitric oxide levels; LIHC cis rs7106204 0.748 rs12293729 chr11:24224679 A/G ch.11.24196551F chr11:24239977 NA 0.79 10.78 0.5 1.56e-23 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2549003 0.966 rs10072571 chr5:131816711 A/C cg02551604 chr5:131831745 NA -0.43 -6.52 -0.33 2.51e-10 Asthma (sex interaction); LIHC cis rs910316 0.737 rs108622 chr14:75481908 A/G cg11812906 chr14:75593930 NEK9 -0.73 -13.75 -0.6 1.54e-34 Height; LIHC cis rs11718455 0.960 rs11929518 chr3:44016874 A/G cg08738300 chr3:44038990 NA 0.52 8.94 0.44 2.46e-17 Coronary artery disease; LIHC cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg21280719 chr6:42927975 GNMT 0.32 7.77 0.39 9.19e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs992157 0.764 rs2015863 chr2:219185161 C/T cg00012203 chr2:219082015 ARPC2 -0.76 -10.68 -0.5 3.57e-23 Colorectal cancer; LIHC cis rs4919694 0.572 rs12240508 chr10:104939232 G/A cg04362960 chr10:104952993 NT5C2 0.8 6.9 0.35 2.59e-11 Arsenic metabolism; LIHC cis rs8180040 0.705 rs73069104 chr3:47280733 T/C cg27129171 chr3:47204927 SETD2 -0.53 -8.35 -0.41 1.72e-15 Colorectal cancer; LIHC cis rs9583531 0.600 rs4773241 chr13:111363021 A/G cg24331049 chr13:111365604 ING1 0.78 13.26 0.58 1.1e-32 Coronary artery disease; LIHC cis rs35110281 0.548 rs2838350 chr21:45109972 T/C cg21573476 chr21:45109991 RRP1B -0.61 -11.46 -0.53 6.02e-26 Mean corpuscular volume; LIHC cis rs1023500 0.529 rs133375 chr22:42466509 C/G cg15557168 chr22:42548783 NA -0.42 -6.62 -0.34 1.37e-10 Schizophrenia; LIHC cis rs7412746 0.658 rs57818453 chr1:150763139 G/A cg18016565 chr1:150552671 MCL1 0.55 10.21 0.48 1.55e-21 Melanoma; LIHC cis rs116095464 0.558 rs9688045 chr5:254035 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs35110281 0.806 rs1454649 chr21:45032982 C/T cg01579765 chr21:45077557 HSF2BP -0.34 -6.48 -0.33 3.23e-10 Mean corpuscular volume; LIHC cis rs6545883 0.868 rs7574631 chr2:61825142 T/G cg14146966 chr2:61757674 XPO1 0.47 8.15 0.4 6.85e-15 Tuberculosis; LIHC cis rs151997 0.962 rs27936 chr5:50181418 T/A cg06027927 chr5:50259733 NA 0.57 7.61 0.38 2.61e-13 Callous-unemotional behaviour; LIHC cis rs7937682 0.737 rs518294 chr11:111424716 A/T cg09085632 chr11:111637200 PPP2R1B -0.75 -9.35 -0.45 1.18e-18 Primary sclerosing cholangitis; LIHC cis rs6748734 1.000 rs4311055 chr2:241821017 T/C cg08694578 chr2:241835147 C2orf54 -0.47 -6.46 -0.33 3.51e-10 Urinary metabolites; LIHC cis rs7542091 0.704 rs4133950 chr1:210044393 C/G cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC cis rs4665809 1.000 rs7599132 chr2:26279810 A/T cg26119090 chr2:26468346 HADHA;HADHB 0.74 9.22 0.45 3.15e-18 Gut microbiome composition (summer); LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg07092213 chr7:1199455 ZFAND2A -0.48 -7.41 -0.37 1e-12 Longevity;Endometriosis; LIHC cis rs7617773 0.780 rs7653152 chr3:48362097 G/C cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.6e-27 Coronary artery disease; LIHC cis rs8067354 0.645 rs16943838 chr17:57839604 C/T cg02344993 chr17:57696989 CLTC 0.71 11.85 0.54 2.25e-27 Hemoglobin concentration; LIHC cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg23283495 chr1:209979779 IRF6 0.44 7.22 0.36 3.3e-12 Cleft lip with or without cleft palate; LIHC cis rs7216064 0.684 rs8182243 chr17:66018505 T/C cg12091567 chr17:66097778 LOC651250 0.84 14.14 0.61 4.52e-36 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs763121 0.626 rs5757236 chr22:39073824 T/C cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.92e-12 Menopause (age at onset); LIHC cis rs7246865 0.954 rs55957788 chr19:17207851 G/A cg16202187 chr19:17186497 HAUS8;MYO9B 0.4 6.04 0.31 4.12e-9 Reticulocyte fraction of red cells; LIHC cis rs9303401 0.659 rs12948133 chr17:56673602 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.29 0.55 5.1e-29 Cognitive test performance; LIHC trans rs3942852 0.696 rs4597030 chr11:48176573 G/A cg15704280 chr7:45808275 SEPT13 -0.59 -8.01 -0.4 1.77e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs55665837 0.540 rs4757261 chr11:14669802 C/A cg25251204 chr11:14927456 NA 0.41 5.87 0.3 1.03e-8 Vitamin D levels; LIHC trans rs4566357 0.615 rs2894626 chr2:227916039 T/C cg16088116 chr21:44841560 SIK1 -0.42 -6.49 -0.33 2.93e-10 Coronary artery disease; LIHC cis rs4654899 0.525 rs12035087 chr1:21471606 T/A cg08539965 chr1:21396338 EIF4G3 -0.32 -5.74 -0.3 2.08e-8 Superior frontal gyrus grey matter volume; LIHC cis rs10876993 0.928 rs1689592 chr12:58057773 C/T cg15848620 chr12:58087721 OS9 -0.54 -7.42 -0.37 9.55e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs12477438 0.784 rs13407840 chr2:99569928 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.5 -0.49 1.5e-22 Chronic sinus infection; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04816434 chr15:22945077 CYFIP1 -0.44 -6.63 -0.34 1.32e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg04546413 chr19:29218101 NA 0.56 10.13 0.48 2.81e-21 Methadone dose in opioid dependence; LIHC cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg03806693 chr22:41940476 POLR3H 0.98 10.53 0.49 1.23e-22 Vitiligo; LIHC cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 9.98 0.47 9.29e-21 Platelet count; LIHC cis rs174601 0.668 rs174559 chr11:61581656 G/A cg27386326 chr11:61587980 NA 0.69 14.03 0.6 1.29e-35 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg22963979 chr7:1858916 MAD1L1 -0.38 -6.19 -0.32 1.73e-9 Bipolar disorder and schizophrenia; LIHC cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg06634786 chr22:41940651 POLR3H 0.81 8.62 0.42 2.59e-16 Vitiligo; LIHC cis rs875971 0.830 rs809025 chr7:65849819 C/G cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg13126279 chr21:47581558 C21orf56 -0.39 -5.96 -0.31 6.17e-9 Testicular germ cell tumor; LIHC trans rs9914544 0.545 rs8078993 chr17:18797126 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.54 -0.33 2.26e-10 Educational attainment (years of education); LIHC cis rs2067615 0.560 rs10467028 chr12:107076405 A/G cg15890332 chr12:107067104 RFX4 0.26 6.19 0.32 1.7e-9 Heart rate; LIHC cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg08888203 chr3:10149979 C3orf24 -0.56 -6.77 -0.34 5.65e-11 Alzheimer's disease; LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg07308232 chr7:1071921 C7orf50 -0.36 -5.81 -0.3 1.43e-8 Longevity;Endometriosis; LIHC cis rs4555082 0.874 rs56263609 chr14:105756944 C/T cg13114125 chr14:105738426 BRF1 -0.79 -9.98 -0.47 9.32e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs3762637 1.000 rs72958458 chr3:122185549 T/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs5769707 0.967 rs8141807 chr22:50043738 C/G cg01652190 chr22:50026171 C22orf34 -0.31 -7.08 -0.36 8.46e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.65 0.38 2.09e-13 Electroencephalogram traits; LIHC cis rs10791097 0.694 rs10791100 chr11:130738946 T/A cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11792861 0.926 rs10512391 chr9:111809530 A/G cg13535736 chr9:111863775 C9orf5 -0.38 -5.78 -0.3 1.71e-8 Menarche (age at onset); LIHC cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg06634786 chr22:41940651 POLR3H 0.8 9.02 0.44 1.43e-17 Vitiligo; LIHC cis rs6570726 0.738 rs6925594 chr6:145898454 T/C cg13319975 chr6:146136371 FBXO30 -0.4 -6.38 -0.33 5.85e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg18630855 chr2:37459194 CEBPZ;C2orf56 -0.42 -6.71 -0.34 7.89e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs61990749 0.544 rs7151211 chr14:78151901 C/A cg21497246 chr14:78225524 SNW1;C14orf178 0.5 7.7 0.38 1.48e-13 Fibroblast growth factor basic levels; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg00280220 chr17:61926910 NA 0.42 6.87 0.35 2.99e-11 Prudent dietary pattern; LIHC cis rs151997 1.000 rs151997 chr5:50233199 A/G cg06027927 chr5:50259733 NA -0.58 -7.91 -0.39 3.53e-14 Callous-unemotional behaviour; LIHC cis rs2153535 0.547 rs9505475 chr6:8542890 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.58e-15 Motion sickness; LIHC cis rs9911578 0.967 rs8075786 chr17:56819216 T/C cg12560992 chr17:57184187 TRIM37 0.95 16.87 0.67 6.67e-47 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs826838 0.967 rs11168299 chr12:38902028 G/T cg26384229 chr12:38710491 ALG10B 0.98 13.3 0.58 7.84e-33 Heart rate; LIHC cis rs67478160 0.643 rs11624184 chr14:104240998 A/G cg08213375 chr14:104286397 PPP1R13B 0.6 10.65 0.5 4.53e-23 Schizophrenia; LIHC cis rs4819052 0.885 rs9980676 chr21:46665430 A/G cg22633049 chr21:46681294 NA -0.37 -6.4 -0.33 5.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7044106 0.762 rs1867254 chr9:123429078 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 8.09 0.4 1.06e-14 Hip circumference adjusted for BMI; LIHC cis rs4919087 1.000 rs3740512 chr10:99078745 C/T cg25902810 chr10:99078978 FRAT1 0.7 10.77 0.5 1.68e-23 Monocyte count; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.69 10.09 0.48 3.89e-21 Lymphocyte counts; LIHC cis rs7582180 0.638 rs9973536 chr2:100942243 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.57 0.42 3.72e-16 Intelligence (multi-trait analysis); LIHC cis rs10461617 0.592 rs6450403 chr5:56062737 A/C cg22800045 chr5:56110881 MAP3K1 0.54 7.05 0.36 1.02e-11 Type 2 diabetes; LIHC cis rs10870270 0.956 rs4131689 chr10:133744328 A/C cg17892150 chr10:133769511 PPP2R2D 0.68 12.94 0.57 1.89e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2404602 0.647 rs11637096 chr15:76931102 T/C cg03037974 chr15:76606532 NA -0.6 -9.92 -0.47 1.49e-20 Blood metabolite levels; LIHC cis rs968567 0.539 rs174556 chr11:61580635 C/T cg07689907 chr11:61582574 FADS1 0.41 5.94 0.31 6.98e-9 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs921968 0.565 rs6733892 chr2:219616002 C/A cg02985541 chr2:219472218 PLCD4 -0.35 -6.13 -0.31 2.4e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs2404602 0.647 rs12903586 chr15:77168240 G/A cg23625390 chr15:77176239 SCAPER -0.56 -9.53 -0.46 3.04e-19 Blood metabolite levels; LIHC cis rs6840360 0.571 rs4696271 chr4:152509118 G/A cg22705602 chr4:152727874 NA -0.32 -6.26 -0.32 1.18e-9 Intelligence (multi-trait analysis); LIHC cis rs798554 0.724 rs798498 chr7:2795882 T/G cg13628971 chr7:2884303 GNA12 0.53 8.02 0.4 1.74e-14 Height; LIHC cis rs16854884 0.633 rs6779321 chr3:143736676 T/C cg06585982 chr3:143692056 C3orf58 0.55 7.17 0.36 4.79e-12 Economic and political preferences (feminism/equality); LIHC cis rs2073499 0.935 rs2236939 chr3:50243510 G/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.51 5.83 0.3 1.27e-8 Schizophrenia; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs17401966 0.838 rs35759975 chr1:10474430 A/T cg19773385 chr1:10388646 KIF1B -0.39 -6.6 -0.34 1.56e-10 Hepatocellular carcinoma; LIHC cis rs7615952 0.673 rs115942855 chr3:125601960 G/A cg05084668 chr3:125655381 ALG1L -0.72 -8.54 -0.42 4.39e-16 Blood pressure (smoking interaction); LIHC cis rs2153535 0.580 rs9505467 chr6:8520219 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.22e-26 Motion sickness; LIHC cis rs1008375 0.898 rs10008445 chr4:17593978 G/T cg02297831 chr4:17616191 MED28 0.46 7.1 0.36 7.4e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7107174 1.000 rs2510054 chr11:77959659 A/G cg02023728 chr11:77925099 USP35 -0.48 -9.28 -0.45 2e-18 Testicular germ cell tumor; LIHC trans rs7618501 1.000 rs7374183 chr3:49785133 G/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.6 -0.34 1.58e-10 Intelligence (multi-trait analysis); LIHC cis rs798554 0.704 rs798503 chr7:2789704 G/A cg19717773 chr7:2847554 GNA12 -0.35 -6.24 -0.32 1.3e-9 Height; LIHC cis rs1198430 1.000 rs1198432 chr1:23756155 C/T cg19827787 chr1:23763612 ASAP3 -0.36 -6.32 -0.32 8.19e-10 Total cholesterol levels; LIHC cis rs17401966 0.931 rs912961 chr1:10356848 A/G cg15208524 chr1:10270712 KIF1B 0.42 6.33 0.32 7.54e-10 Hepatocellular carcinoma; LIHC cis rs13108904 0.775 rs2279282 chr4:1216033 G/C cg02980000 chr4:1222292 CTBP1 -0.53 -7.33 -0.37 1.63e-12 Obesity-related traits; LIHC cis rs9581857 0.685 rs9319370 chr13:28042493 G/T cg22138327 chr13:27999177 GTF3A 0.76 6.26 0.32 1.17e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg03806693 chr22:41940476 POLR3H -0.96 -11.14 -0.52 8.25e-25 Vitiligo; LIHC cis rs1190552 1.000 rs1190552 chr14:102911907 A/G cg10241871 chr14:102965420 TECPR2 0.46 7.13 0.36 6.16e-12 Blood protein levels; LIHC cis rs7020830 0.823 rs13285624 chr9:37129496 T/G cg14294708 chr9:37120828 ZCCHC7 1.17 26.38 0.82 1.97e-84 Schizophrenia; LIHC cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg00825309 chr19:58991885 ZNF446 -0.53 -8.28 -0.41 2.8e-15 Uric acid clearance; LIHC cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg16049864 chr8:95962084 TP53INP1 -0.63 -11.88 -0.54 1.78e-27 Type 2 diabetes; LIHC cis rs57221529 0.713 rs12522724 chr5:590742 T/C cg09021430 chr5:549028 NA -0.43 -8.53 -0.42 4.8e-16 Lung disease severity in cystic fibrosis; LIHC cis rs9300255 0.506 rs11057251 chr12:123791227 A/G cg00376283 chr12:123451042 ABCB9 -0.62 -10.23 -0.48 1.32e-21 Neutrophil percentage of white cells; LIHC cis rs1005277 0.579 rs2474563 chr10:38375938 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3853824 1.000 rs2197258 chr17:54878582 A/T cg13675837 chr17:54910204 DGKE 0.39 5.88 0.3 9.79e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7116495 0.609 rs1541304 chr11:71714078 T/C cg26138937 chr11:71823887 C11orf51 -1.32 -10.9 -0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs769267 0.930 rs4808203 chr19:19568659 A/G cg21559469 chr19:19431446 KIAA0892;SF4 0.43 6.04 0.31 3.98e-9 Tonsillectomy; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21953508 chr4:38690502 KLF3 0.48 6.4 0.33 5.2e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9640161 0.742 rs2108853 chr7:150017589 A/C cg21361702 chr7:150065534 REPIN1 0.45 6.15 0.32 2.17e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs7131987 0.903 rs10843367 chr12:29408380 G/A cg14222432 chr12:29376421 FAR2 0.36 6.91 0.35 2.42e-11 QT interval; LIHC cis rs17376456 0.877 rs17083460 chr5:93462354 A/G cg25358565 chr5:93447407 FAM172A 1.12 10.35 0.49 5.17e-22 Diabetic retinopathy; LIHC cis rs116095464 0.558 rs62344300 chr5:246336 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.7 -0.5 3.15e-23 Breast cancer; LIHC cis rs9768139 0.935 rs7782393 chr7:158120486 G/A cg25566285 chr7:158114605 PTPRN2 -0.26 -7.64 -0.38 2.14e-13 Calcium levels; LIHC cis rs1005277 0.579 rs116912400 chr10:38479207 G/T cg00409905 chr10:38381863 ZNF37A -0.57 -9.48 -0.46 4.29e-19 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.807 rs10880234 chr12:38318353 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.21 0.41 4.74e-15 Bladder cancer; LIHC cis rs7772486 0.875 rs2073287 chr6:146350264 T/C cg23711669 chr6:146136114 FBXO30 0.59 10.44 0.49 2.54e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs7551222 0.681 rs2045623 chr1:204497413 A/G cg20240347 chr1:204465584 NA -0.36 -7.68 -0.38 1.64e-13 Schizophrenia; LIHC cis rs17125944 0.505 rs28568967 chr14:53223060 A/G cg00686598 chr14:53173677 PSMC6 1.2 15.24 0.64 2.21e-40 Alzheimer's disease (late onset); LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg14709524 chr16:89940631 TCF25 0.55 7.23 0.36 3.12e-12 Skin colour saturation; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg19318889 chr4:1322082 MAEA 0.64 10.22 0.48 1.4e-21 Longevity; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07050032 chr17:78009173 CCDC40;TBC1D16 -0.53 -6.15 -0.32 2.17e-9 Systolic blood pressure; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24316073 chr7:150773456 SLC4A2 0.36 6.16 0.32 1.99e-9 Longevity; LIHC cis rs10411936 0.712 rs8103521 chr19:16589750 A/G cg10248733 chr19:16607483 C19orf44;CALR3 0.51 6.9 0.35 2.57e-11 White blood cell count;Multiple sclerosis; LIHC cis rs9513627 1.000 rs6491512 chr13:100199741 C/T cg25919922 chr13:100150906 NA 0.77 6.89 0.35 2.62e-11 Obesity-related traits; LIHC cis rs7584330 0.868 rs58057291 chr2:238395479 T/A cg14458575 chr2:238380390 NA 0.48 7.21 0.36 3.64e-12 Prostate cancer; LIHC cis rs1816752 1.000 rs7988810 chr13:25019096 T/C cg22771759 chr13:24902376 NA 0.31 6.44 0.33 4.02e-10 Obesity-related traits; LIHC trans rs2018683 0.834 rs733485 chr7:29026685 C/A cg19402173 chr7:128379420 CALU -0.4 -6.42 -0.33 4.6e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg02990361 chr1:107599529 PRMT6 0.59 9.78 0.47 4.29e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17213078 0.602 rs4851926 chr2:106742660 A/G cg16099169 chr2:106886729 NA 0.43 6.53 0.33 2.36e-10 Facial morphology (factor 23); LIHC cis rs35306767 0.953 rs12357633 chr10:957246 C/T cg26597838 chr10:835615 NA 1.18 12.71 0.57 1.35e-30 Eosinophil percentage of granulocytes; LIHC cis rs2932538 0.922 rs6668533 chr1:113064468 C/T cg22162597 chr1:113214053 CAPZA1 0.65 9.09 0.44 8.3e-18 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs595982 0.527 rs55706579 chr19:49382969 G/A cg21252483 chr19:49399788 TULP2 -0.98 -10.98 -0.51 3.08e-24 Red cell distribution width; LIHC cis rs1046896 0.562 rs9912684 chr17:80873067 C/T cg02711726 chr17:80685570 FN3KRP -0.4 -7.16 -0.36 4.91e-12 Glycated hemoglobin levels; LIHC cis rs6461049 0.734 rs1558465 chr7:2151398 G/C cg14004847 chr7:1930337 MAD1L1 -0.42 -6.19 -0.32 1.71e-9 Schizophrenia; LIHC cis rs2742540 0.503 rs11042121 chr11:8932640 A/C cg12365402 chr11:9010492 NRIP3 0.27 6.2 0.32 1.63e-9 Hematocrit; LIHC cis rs10508774 1.000 rs72793580 chr10:32725421 C/T cg01819863 chr10:32635814 EPC1 0.67 6.23 0.32 1.37e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10423674 0.526 rs11085241 chr19:18828546 G/A cg14292368 chr19:18793705 CRTC1 -0.42 -5.82 -0.3 1.34e-8 Menarche (age at onset); LIHC cis rs1552244 0.882 rs9757159 chr3:10039166 C/T cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15483964 chr1:16482439 EPHA2 -0.51 -6.14 -0.32 2.25e-9 Systolic blood pressure; LIHC cis rs6586163 0.872 rs7082101 chr10:90741615 C/A cg03111039 chr10:90751583 FAS;ACTA2 -0.53 -7.78 -0.39 8.86e-14 Chronic lymphocytic leukemia; LIHC cis rs4808199 0.894 rs10418051 chr19:19397789 C/T cg03709012 chr19:19516395 GATAD2A 1.01 16.65 0.67 5.29e-46 Nonalcoholic fatty liver disease; LIHC cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.58 0.46 2.06e-19 Bipolar disorder; LIHC cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg23758822 chr17:41437982 NA 0.94 17.79 0.69 1.4e-50 Menopause (age at onset); LIHC trans rs61931739 0.500 rs7296061 chr12:34435009 A/G cg26384229 chr12:38710491 ALG10B -0.76 -9.33 -0.45 1.32e-18 Morning vs. evening chronotype; LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg22029157 chr1:209979665 IRF6 0.48 8.02 0.4 1.69e-14 Cleft lip with or without cleft palate; LIHC cis rs4908768 0.501 rs7527389 chr1:8556545 A/G cg20416874 chr1:8611966 RERE -0.67 -14.23 -0.61 2.07e-36 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7208859 0.623 rs7223404 chr17:29107363 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg25894440 chr7:65020034 NA 0.53 6.07 0.31 3.34e-9 Diabetic kidney disease; LIHC cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg05025164 chr4:1340916 KIAA1530 0.43 6.32 0.32 7.96e-10 Longevity; LIHC cis rs6952808 0.931 rs7810038 chr7:1894116 T/C cg22963979 chr7:1858916 MAD1L1 -0.41 -6.54 -0.33 2.19e-10 Bipolar disorder and schizophrenia; LIHC cis rs6815814 0.861 rs10034903 chr4:38784678 C/G cg06935464 chr4:38784597 TLR10 0.53 9.33 0.45 1.41e-18 Breast cancer; LIHC cis rs7937682 0.575 rs7127010 chr11:111770782 C/T cg09085632 chr11:111637200 PPP2R1B 0.94 13.48 0.59 1.64e-33 Primary sclerosing cholangitis; LIHC cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg19774624 chr17:42201019 HDAC5 -0.83 -12.88 -0.57 3.19e-31 Total body bone mineral density; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg12424548 chr11:2591932 KCNQ1 0.36 6.04 0.31 4.1e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs739401 0.566 rs7931504 chr11:3026712 C/T cg05729581 chr11:3078854 CARS -0.43 -6.0 -0.31 5.04e-9 Longevity; LIHC cis rs7208859 0.673 rs56085216 chr17:29217234 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2710642 0.564 rs60144282 chr2:62843163 G/T cg17519650 chr2:63277830 OTX1 0.46 7.29 0.37 2.19e-12 LDL cholesterol levels;LDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18404039 chr20:3184938 DDRGK1 0.47 6.44 0.33 4.01e-10 Lung function (FEV1/FVC); LIHC cis rs11626933 1.000 rs6575122 chr14:90753556 A/G cg07150772 chr14:90864620 CALM1 -0.41 -5.83 -0.3 1.29e-8 Gut microbiota (bacterial taxa); LIHC cis rs7927771 0.832 rs4752994 chr11:47411065 A/T cg20135002 chr11:47629003 NA 0.52 8.72 0.43 1.26e-16 Subjective well-being; LIHC cis rs986417 0.818 rs10142842 chr14:61085205 C/T cg27398547 chr14:60952738 C14orf39 -0.67 -7.54 -0.38 4.33e-13 Gut microbiota (bacterial taxa); LIHC trans rs875971 0.660 rs801211 chr7:66015689 T/G cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC cis rs6424115 1.000 rs6697805 chr1:24151996 C/A cg15997130 chr1:24165203 NA -0.47 -9.61 -0.46 1.6e-19 Immature fraction of reticulocytes; LIHC trans rs1493916 0.748 rs1941684 chr18:31304421 C/G cg27147174 chr7:100797783 AP1S1 -0.47 -6.55 -0.33 2.17e-10 Life satisfaction; LIHC cis rs9611565 0.512 rs6519289 chr22:42170432 A/C cg06634786 chr22:41940651 POLR3H 0.72 7.26 0.37 2.61e-12 Vitiligo; LIHC cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -9.49 -0.46 3.97e-19 Platelet count; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg08219700 chr8:58056026 NA 0.53 6.96 0.35 1.71e-11 Developmental language disorder (linguistic errors); LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg04779191 chr16:69166964 CHTF8;CIRH1A 0.4 6.51 0.33 2.6200000000000003e-10 Metabolic traits; LIHC cis rs7091068 0.616 rs7093903 chr10:95484010 C/T cg20715218 chr10:95462985 C10orf4 -0.52 -5.97 -0.31 5.87e-9 Urinary tract infection frequency; LIHC cis rs4699052 0.662 rs1400363 chr4:104250722 A/C cg16532752 chr4:104119610 CENPE -0.37 -5.72 -0.3 2.32e-8 Testicular germ cell tumor; LIHC trans rs4824093 0.535 rs73443931 chr22:50291603 G/A cg09872104 chr7:134855509 C7orf49 -0.78 -6.31 -0.32 8.48e-10 Amyotrophic lateral sclerosis (sporadic); LIHC trans rs2727020 0.521 rs11039902 chr11:48679467 A/G cg03929089 chr4:120376271 NA -0.43 -6.58 -0.34 1.78e-10 Coronary artery disease; LIHC cis rs151349 1.000 rs151345 chr20:57586849 G/C cg23907860 chr20:57583709 CTSZ -0.44 -7.18 -0.36 4.35e-12 Platelet distribution width; LIHC cis rs11608355 0.545 rs12822974 chr12:109909154 G/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs2066819 1.000 rs78495928 chr12:56635080 G/C cg26714650 chr12:56694279 CS -1.33 -12.81 -0.57 5.98e-31 Psoriasis vulgaris; LIHC cis rs7523273 0.526 rs1204708 chr1:208024062 G/C cg22525895 chr1:207977042 MIR29B2 -0.59 -9.2 -0.45 3.5e-18 Schizophrenia; LIHC cis rs2932538 0.922 rs6663922 chr1:113095948 T/C cg22162597 chr1:113214053 CAPZA1 0.66 10.35 0.49 5.05e-22 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs9325144 0.555 rs4882359 chr12:38726679 T/C cg26384229 chr12:38710491 ALG10B 0.59 8.28 0.41 2.77e-15 Morning vs. evening chronotype; LIHC cis rs7674212 0.541 rs11727498 chr4:104100987 C/T cg16532752 chr4:104119610 CENPE -0.42 -6.66 -0.34 1.06e-10 Type 2 diabetes; LIHC cis rs1570884 0.516 rs9316462 chr13:50176321 A/G cg08779649 chr13:50194554 NA 0.35 6.38 0.33 5.59e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg05564831 chr3:52568323 NT5DC2 0.37 6.0 0.31 5.11e-9 Electroencephalogram traits; LIHC cis rs7584330 0.554 rs77180399 chr2:238442951 G/A cg08992911 chr2:238395768 MLPH 0.55 6.05 0.31 3.84e-9 Prostate cancer; LIHC cis rs2204008 0.658 rs12371956 chr12:38298010 A/T cg26384229 chr12:38710491 ALG10B 0.6 8.19 0.4 5.23e-15 Bladder cancer; LIHC trans rs2727020 0.615 rs35423199 chr11:49514914 T/C cg15704280 chr7:45808275 SEPT13 -1.0 -22.08 -0.77 9.16e-68 Coronary artery disease; LIHC cis rs12586317 0.620 rs28404080 chr14:35539418 G/T cg05294307 chr14:35346193 BAZ1A -0.46 -6.72 -0.34 7.6e-11 Psoriasis; LIHC cis rs11958404 0.932 rs12517979 chr5:157428918 T/C cg05962755 chr5:157440814 NA 0.97 10.89 0.51 6.51e-24 IgG glycosylation; LIHC trans rs11098499 0.954 rs10518331 chr4:120323595 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs56235845 0.694 rs11748912 chr5:176765395 G/A cg16006841 chr5:176797999 RGS14 0.56 7.62 0.38 2.51e-13 Hemoglobin concentration;Hematocrit; LIHC trans rs877282 0.853 rs12777155 chr10:754731 G/C cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs6933660 0.745 rs9397405 chr6:151736084 G/T cg10883421 chr6:151773342 RMND1;C6orf211 0.66 11.14 0.52 8.37e-25 Menarche (age at onset); LIHC cis rs10193935 1.000 rs62144748 chr2:42419468 C/T cg27598129 chr2:42591480 NA -0.72 -11.21 -0.52 4.73e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.66 9.43 0.45 6.58e-19 Lymphocyte counts; LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg10150615 chr22:24372951 LOC391322 0.51 7.42 0.37 9.34e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2204008 0.687 rs1733404 chr12:38123395 G/T cg13010199 chr12:38710504 ALG10B -0.48 -5.78 -0.3 1.71e-8 Bladder cancer; LIHC cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg08132940 chr7:1081526 C7orf50 -0.83 -6.87 -0.35 3.01e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17021463 0.902 rs10516950 chr4:95254730 C/T cg11021082 chr4:95130006 SMARCAD1 0.45 8.38 0.41 1.43e-15 Testicular germ cell tumor; LIHC cis rs12928939 0.815 rs1345868 chr16:71669624 G/T cg03805757 chr16:71968109 PKD1L3 -0.47 -5.81 -0.3 1.43e-8 Post bronchodilator FEV1; LIHC cis rs238295 0.805 rs1056244 chr20:5551034 G/C cg24001556 chr20:5591874 RP5-1022P6.2 -0.53 -7.19 -0.36 4.16e-12 Occipital cortical area (total cortical area interaction); LIHC cis rs908922 0.887 rs1415432 chr1:152480654 G/A cg20991723 chr1:152506922 NA 0.4 6.15 0.32 2.19e-9 Hair morphology; LIHC cis rs7208859 0.673 rs9891413 chr17:29208209 G/C cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 1.000 rs811880 chr7:65818646 T/C cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg11062466 chr8:58055876 NA 0.53 6.91 0.35 2.35e-11 Developmental language disorder (linguistic errors); LIHC cis rs15676 0.947 rs2293968 chr9:131587240 G/A cg00228799 chr9:131580591 ENDOG 0.46 7.1 0.36 7.08e-12 Blood metabolite levels; LIHC cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg21782813 chr7:2030301 MAD1L1 0.4 6.83 0.35 3.94e-11 Schizophrenia; LIHC cis rs9916302 0.555 rs12940193 chr17:37652178 T/G cg03013999 chr17:37608204 MED1 0.35 5.74 0.3 2.11e-8 Glomerular filtration rate (creatinine); LIHC cis rs4665809 1.000 rs6546728 chr2:26276531 G/C cg04944784 chr2:26401820 FAM59B -0.68 -8.43 -0.41 9.85e-16 Gut microbiome composition (summer); LIHC cis rs7592578 0.771 rs1128723 chr2:191366707 A/G cg27211696 chr2:191398769 TMEM194B -0.6 -8.09 -0.4 1.05e-14 Diastolic blood pressure; LIHC cis rs600806 0.676 rs2781553 chr1:110026989 G/T cg02415029 chr1:110025642 ATXN7L2 0.46 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs6582618 1 rs6582618 chr12:38726137 A/G cg26384229 chr12:38710491 ALG10B 0.56 7.72 0.39 1.3e-13 Morning vs. evening chronotype; LIHC cis rs62005083 0.541 rs61059815 chr14:74536465 A/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.49 6.5 0.33 2.88e-10 Mean corpuscular volume; LIHC cis rs7552404 1.000 rs7516226 chr1:76234257 G/A cg22875332 chr1:76189707 ACADM 0.46 6.39 0.33 5.38e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1580019 0.883 rs6945294 chr7:32472099 G/A cg06627557 chr7:32535165 LSM5;AVL9 0.93 15.26 0.64 1.83e-40 Cognitive ability; LIHC cis rs600806 0.665 rs1368988 chr1:110012123 A/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.58 -0.38 3.35e-13 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.584 rs9502723 chr6:8541504 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.66 0.42 1.89e-16 Motion sickness; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg16821904 chr2:87169999 RGPD1;RGPD2 0.36 6.92 0.35 2.17e-11 Bilirubin levels; LIHC cis rs3849570 0.961 rs11915042 chr3:81834060 G/A cg07356753 chr3:81810745 GBE1 -0.63 -10.59 -0.5 7.33e-23 Waist circumference;Body mass index; LIHC cis rs9297145 0.565 rs7794690 chr7:98764768 G/A cg05967295 chr7:98741636 SMURF1 -0.39 -6.46 -0.33 3.6e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs6088590 0.735 rs6088618 chr20:33409350 G/A cg24642439 chr20:33292090 TP53INP2 0.57 7.89 0.39 4.21e-14 Coronary artery disease; LIHC cis rs3784262 1.000 rs12908953 chr15:58277812 A/G cg12031962 chr15:58353849 ALDH1A2 -0.34 -6.54 -0.33 2.27e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs12579753 0.956 rs34146892 chr12:82188581 T/G cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC cis rs1707322 0.789 rs7540578 chr1:46252144 C/T cg03146154 chr1:46216737 IPP 0.53 9.0 0.44 1.59e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg25631650 chr19:633157 POLRMT 0.38 6.12 0.31 2.62e-9 Metabolic traits; LIHC cis rs8053891 0.614 rs34235351 chr16:71987875 G/A cg01557791 chr16:72042693 DHODH -0.42 -6.25 -0.32 1.24e-9 Coronary artery disease; LIHC cis rs3960554 0.529 rs7800970 chr7:75880198 C/T cg01364799 chr7:75623366 TMEM120A 0.46 6.66 0.34 1.08e-10 Eotaxin levels; LIHC cis rs427394 0.664 rs274701 chr5:6728707 C/A cg10857441 chr5:6722123 POLS -0.35 -6.06 -0.31 3.69e-9 Menopause (age at onset); LIHC trans rs916888 0.773 rs199445 chr17:44817408 C/T cg07870213 chr5:140052090 DND1 1.02 10.59 0.5 7.69e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg27286337 chr10:134555280 INPP5A 0.91 13.07 0.58 5.94e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg10755058 chr3:40428713 ENTPD3 0.4 6.67 0.34 1.04e-10 Renal cell carcinoma; LIHC cis rs7172677 0.501 rs8040061 chr15:75393720 C/A cg15902774 chr15:75289873 SCAMP5 0.34 5.96 0.31 6.21e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11673344 0.864 rs8108727 chr19:37581524 T/C cg27390819 chr19:37464633 NA -0.51 -6.19 -0.32 1.73e-9 Obesity-related traits; LIHC cis rs875971 0.660 rs10950044 chr7:66042976 A/G cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.97e-24 Aortic root size; LIHC cis rs6782228 0.651 rs9852825 chr3:128387357 C/G cg16766828 chr3:128327626 NA -0.43 -6.77 -0.34 5.68e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs6502050 0.842 rs7218075 chr17:80076808 C/G cg11859384 chr17:80120422 CCDC57 0.43 5.9 0.3 8.52e-9 Life satisfaction; LIHC cis rs5769707 0.609 rs2071890 chr22:50001291 G/A cg07959070 chr22:50026188 C22orf34 -0.35 -8.95 -0.44 2.35e-17 Monocyte count;Monocyte percentage of white cells; LIHC cis rs4819052 0.819 rs7279136 chr21:46692287 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.33 0.41 2.02e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs34779708 0.931 rs11010125 chr10:35502953 A/G cg03585969 chr10:35415529 CREM 0.85 12.77 0.57 8.07e-31 Inflammatory bowel disease;Crohn's disease; LIHC trans rs2243480 0.803 rs55700941 chr7:65389800 T/A cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs7772486 0.686 rs10872579 chr6:145966012 C/G cg23711669 chr6:146136114 FBXO30 0.63 11.43 0.53 7.57e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.89 8.56 0.42 3.93e-16 Platelet count; LIHC cis rs7937682 0.883 rs517982 chr11:111462687 T/C cg09085632 chr11:111637200 PPP2R1B -0.92 -11.22 -0.52 4.43e-25 Primary sclerosing cholangitis; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC trans rs1814175 0.502 rs12365889 chr11:49623034 G/A cg03929089 chr4:120376271 NA -0.67 -9.85 -0.47 2.55e-20 Height; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg27572074 chr19:42419406 NA -0.5 -6.76 -0.34 5.92e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11098499 0.754 rs17049949 chr4:120255290 A/G cg09307838 chr4:120376055 NA 0.7 11.05 0.51 1.72e-24 Corneal astigmatism; LIHC cis rs986417 0.901 rs10782440 chr14:61031648 G/C cg27398547 chr14:60952738 C14orf39 0.79 8.86 0.43 4.51e-17 Gut microbiota (bacterial taxa); LIHC cis rs727505 1.000 rs56321835 chr7:124529622 T/C cg23710748 chr7:124431027 NA -0.32 -5.71 -0.3 2.44e-8 Lewy body disease; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.830 rs10896339 chr11:68302846 G/C cg16797656 chr11:68205561 LRP5 0.55 8.89 0.43 3.56e-17 Total body bone mineral density; LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.38 6.12 0.31 2.63e-9 Prudent dietary pattern; LIHC cis rs6430585 0.528 rs309167 chr2:136669264 C/T cg07169764 chr2:136633963 MCM6 1.29 21.48 0.76 2.15e-65 Corneal structure; LIHC cis rs738322 0.553 rs28718653 chr22:38570698 C/A cg25457927 chr22:38595422 NA -0.32 -7.25 -0.36 2.84e-12 Cutaneous nevi; LIHC cis rs2404602 0.716 rs67204011 chr15:76846555 C/T cg03037974 chr15:76606532 NA 0.75 14.59 0.62 8.08e-38 Blood metabolite levels; LIHC cis rs7927592 0.956 rs7102273 chr11:68385579 T/C cg16797656 chr11:68205561 LRP5 0.5 7.83 0.39 6.08e-14 Total body bone mineral density; LIHC cis rs16828019 0.852 rs71648534 chr1:41613747 G/T cg03387723 chr1:41708464 SCMH1 -0.45 -7.22 -0.36 3.37e-12 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.505 rs719569 chr10:38154415 T/G cg23533926 chr12:111358616 MYL2 0.33 6.47 0.33 3.34e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2235573 0.527 rs139865 chr22:38353932 C/G cg03989125 chr22:38214979 NA -0.42 -5.83 -0.3 1.26e-8 Glioblastoma;Glioma; LIHC cis rs4819052 0.851 rs2330011 chr21:46658498 G/A cg22633049 chr21:46681294 NA -0.36 -6.29 -0.32 9.51e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7677751 0.806 rs7682912 chr4:55085620 T/G cg17187183 chr4:55093834 PDGFRA 0.61 7.55 0.38 3.87e-13 Corneal astigmatism; LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg09177884 chr7:1199841 ZFAND2A -0.44 -6.4 -0.33 5.21e-10 Longevity;Endometriosis; LIHC cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg18279126 chr7:2041391 MAD1L1 0.36 5.95 0.31 6.6e-9 Bipolar disorder and schizophrenia; LIHC cis rs9522267 0.535 rs9515447 chr13:112222303 C/T cg10483660 chr13:112241077 NA -0.23 -6.09 -0.31 3.03e-9 Hepatitis; LIHC cis rs600806 0.888 rs2228604 chr1:109884775 A/C cg16275483 chr1:110013120 SYPL2 -0.5 -6.35 -0.32 6.94e-10 Intelligence (multi-trait analysis); LIHC cis rs4700695 0.841 rs251305 chr5:65249859 C/T cg21114390 chr5:65439923 SFRS12 0.49 6.63 0.34 1.3e-10 Facial morphology (factor 19); LIHC cis rs6942756 0.806 rs10257620 chr7:128901429 C/A cg02491457 chr7:128862824 NA 0.67 11.13 0.52 8.9e-25 White matter hyperintensity burden; LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.56 8.82 0.43 5.84e-17 Height; LIHC cis rs2191566 0.960 rs11083733 chr19:44520919 G/C cg18700516 chr19:44507157 ZNF230 -0.35 -5.86 -0.3 1.11e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs9503598 0.543 rs4959832 chr6:3435112 A/C cg00476032 chr6:3446245 SLC22A23 -0.33 -5.99 -0.31 5.28e-9 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs2073300 0.609 rs34648279 chr20:23402935 T/G cg16736954 chr20:23401023 NAPB 0.72 8.46 0.42 7.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6088590 1.000 rs6119524 chr20:33373813 C/T cg06115741 chr20:33292138 TP53INP2 0.57 7.86 0.39 5.19e-14 Coronary artery disease; LIHC cis rs3823572 0.586 rs2953625 chr7:133657789 A/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs6665290 0.904 rs11578103 chr1:227189642 C/A cg10327440 chr1:227177885 CDC42BPA -1.18 -25.59 -0.81 1.83e-81 Myeloid white cell count; LIHC cis rs10056811 0.538 rs3923323 chr5:74372141 C/T cg00601450 chr5:74908170 NA -0.56 -6.74 -0.34 6.81e-11 Coronary artery disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05651185 chr6:125421530 NA -0.34 -6.07 -0.31 3.41e-9 Calcium levels; LIHC cis rs1862618 0.525 rs2662016 chr5:56269047 A/G cg12311346 chr5:56204834 C5orf35 0.63 7.97 0.4 2.46e-14 Initial pursuit acceleration; LIHC cis rs6762477 0.748 rs2073726 chr3:50223593 T/A cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.51 -7.11 -0.36 6.66e-12 Menarche (age at onset); LIHC cis rs317689 0.918 rs581911 chr12:69738293 C/T cg20891283 chr12:69753455 YEATS4 0.68 10.64 0.5 4.84e-23 Response to diuretic therapy; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg08677398 chr8:58056175 NA 0.41 6.32 0.32 8.32e-10 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27221266 chr10:96122679 NOC3L 0.57 8.17 0.4 6.13e-15 Pancreatic cancer; LIHC cis rs9381040 0.610 rs6919961 chr6:41020361 T/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.22 -0.32 1.43e-9 Alzheimer's disease (late onset); LIHC cis rs3760982 0.546 rs73048681 chr19:44289945 T/C cg11993925 chr19:44307056 LYPD5 0.31 6.87 0.35 2.98e-11 Breast cancer (estrogen-receptor negative);Breast cancer; LIHC trans rs1005277 0.522 rs11011343 chr10:38002698 A/G cg17830980 chr10:43048298 ZNF37B -0.41 -7.96 -0.4 2.58e-14 Extrinsic epigenetic age acceleration; LIHC cis rs807029 0.533 rs3824783 chr10:102750851 C/T cg17130504 chr10:102756923 LZTS2 0.54 7.53 0.38 4.48e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs12611088 0.510 rs1133929 chr19:43983740 T/C cg13740135 chr19:44006432 PHLDB3 -0.42 -6.2 -0.32 1.58e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02971882 chr4:71554083 UTP3 -0.43 -6.59 -0.34 1.71e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg05368731 chr17:41323189 NBR1 0.72 12.37 0.56 2.77e-29 Menopause (age at onset); LIHC cis rs2115630 0.846 rs8024538 chr15:85368419 A/T cg11189052 chr15:85197271 WDR73 -0.45 -6.49 -0.33 2.98e-10 P wave terminal force; LIHC cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg25894440 chr7:65020034 NA -0.54 -6.31 -0.32 8.47e-10 Diabetic kidney disease; LIHC cis rs2991971 0.716 rs7532573 chr1:45915892 A/T cg05343316 chr1:45956843 TESK2 0.45 6.63 0.34 1.33e-10 High light scatter reticulocyte count; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg15383120 chr6:291909 DUSP22 -0.52 -7.12 -0.36 6.43e-12 Menopause (age at onset); LIHC cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg15691649 chr6:25882328 NA -0.54 -7.82 -0.39 6.76e-14 Blood metabolite levels; LIHC cis rs11711311 0.868 rs13091621 chr3:113481977 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.3 0.41 2.45e-15 IgG glycosylation; LIHC cis rs28595532 0.623 rs34284204 chr4:119227672 C/T cg21605333 chr4:119757512 SEC24D 0.8 6.87 0.35 3.14e-11 Cannabis dependence symptom count; LIHC trans rs7618501 0.602 rs2526754 chr3:50125996 G/A cg21659725 chr3:3221576 CRBN -0.68 -10.84 -0.51 9.9899999999999993e-24 Intelligence (multi-trait analysis); LIHC cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg10295955 chr4:187884368 NA -0.98 -22.85 -0.78 8.02e-71 Lobe attachment (rater-scored or self-reported); LIHC cis rs11031096 0.655 rs10835736 chr11:4212013 G/A cg18678763 chr11:4115507 RRM1 -0.39 -5.73 -0.3 2.17e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10791097 0.694 rs2236717 chr11:130739887 G/T cg12179176 chr11:130786555 SNX19 0.81 13.05 0.58 7.15e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1707322 1.000 rs1622208 chr1:46498375 A/G cg03146154 chr1:46216737 IPP -0.47 -7.44 -0.37 8.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg11062466 chr8:58055876 NA 0.47 6.43 0.33 4.25e-10 Developmental language disorder (linguistic errors); LIHC trans rs7615952 1.000 rs7615952 chr3:125649403 A/C cg07211511 chr3:129823064 LOC729375 0.79 10.13 0.48 2.96e-21 Blood pressure (smoking interaction); LIHC cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg13397359 chr6:42928475 GNMT 0.67 9.84 0.47 2.78e-20 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs12549902 1.000 rs12549902 chr8:41509259 C/T cg21772509 chr8:41503840 NKX6-3 0.42 6.77 0.34 5.56e-11 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs936229 0.749 rs4886633 chr15:75178207 G/A cg14664628 chr15:75095509 CSK -0.72 -9.57 -0.46 2.2e-19 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs644799 0.601 rs662168 chr11:95586982 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.62 10.7 0.5 3.14e-23 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs921968 0.643 rs589967 chr2:219445165 T/C cg17980119 chr2:219472607 PLCD4 0.34 5.88 0.3 9.92e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs9649213 0.593 rs6967457 chr7:97912221 T/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.95 -0.31 6.78e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs875971 0.862 rs6460302 chr7:65960257 C/G cg11764359 chr7:65958608 NA 0.84 15.05 0.63 1.27e-39 Aortic root size; LIHC cis rs35110281 0.840 rs2838331 chr21:45026728 A/G cg04455712 chr21:45112962 RRP1B -0.44 -7.27 -0.37 2.5e-12 Mean corpuscular volume; LIHC cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg02187348 chr16:89574699 SPG7 0.68 10.97 0.51 3.31e-24 Multiple myeloma (IgH translocation); LIHC cis rs10751667 0.643 rs10751669 chr11:942344 C/G cg06064525 chr11:970664 AP2A2 0.55 15.16 0.63 4.37e-40 Alzheimer's disease (late onset); LIHC cis rs490234 0.966 rs545900 chr9:128341278 C/T cg14078157 chr9:128172775 NA 0.34 5.86 0.3 1.11e-8 Mean arterial pressure; LIHC cis rs8044995 0.563 rs57434514 chr16:68402649 G/A cg05110241 chr16:68378359 PRMT7 -0.83 -9.0 -0.44 1.55e-17 Schizophrenia; LIHC cis rs1707322 0.963 rs34907901 chr1:46405214 T/G cg03146154 chr1:46216737 IPP 0.48 7.68 0.38 1.72e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08237663 chr3:130745839 NEK11;ASTE1 0.41 6.18 0.32 1.83e-9 Cognitive function; LIHC cis rs992157 1.000 rs10932766 chr2:219122090 G/A cg00012203 chr2:219082015 ARPC2 0.91 14.98 0.63 2.4e-39 Colorectal cancer; LIHC cis rs2108622 0.649 rs113055956 chr19:15977312 T/A cg13772218 chr19:15982569 NA 0.37 7.87 0.39 4.72e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07744623 chr20:44462345 SNX21 0.5 6.71 0.34 7.86e-11 Lung function (FEV1/FVC); LIHC cis rs797680 0.856 rs10874762 chr1:93639101 T/G cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.67e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs9733 0.596 rs17606613 chr1:150683015 C/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg03721293 chr16:90014378 DEF8 0.36 6.31 0.32 8.62e-10 Skin colour saturation; LIHC cis rs208520 1.000 rs208529 chr6:66957549 T/C cg07460842 chr6:66804631 NA -0.65 -6.99 -0.35 1.44e-11 Exhaled nitric oxide output; LIHC cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg02290350 chr8:58132656 NA 0.4 8.41 0.41 1.13e-15 Developmental language disorder (linguistic errors); LIHC cis rs2439831 0.681 rs484846 chr15:43600803 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.74 11.0 0.51 2.72e-24 Lung cancer in ever smokers; LIHC cis rs9322817 0.691 rs6571207 chr6:105242161 A/C cg02098413 chr6:105308735 HACE1 -0.41 -7.62 -0.38 2.5e-13 Thyroid stimulating hormone; LIHC cis rs2425143 1.000 rs6060588 chr20:34337480 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.84 -0.3 1.2e-8 Blood protein levels; LIHC cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.16 -0.44 5.01e-18 Bipolar disorder; LIHC cis rs9513627 1.000 rs4584676 chr13:100160560 A/G cg25919922 chr13:100150906 NA 0.77 7.05 0.36 1.01e-11 Obesity-related traits; LIHC trans rs61931739 0.517 rs7958856 chr12:34294737 T/C cg26384229 chr12:38710491 ALG10B 0.56 7.28 0.37 2.27e-12 Morning vs. evening chronotype; LIHC cis rs4730268 0.950 rs2158837 chr7:107440451 C/T cg18560240 chr7:107437656 SLC26A3 -0.51 -6.29 -0.32 9.84e-10 IgG glycosylation; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.59 9.01 0.44 1.44e-17 Height; LIHC trans rs1005277 0.522 rs200943 chr10:38148730 A/G cg17830980 chr10:43048298 ZNF37B -0.46 -8.85 -0.43 4.66e-17 Extrinsic epigenetic age acceleration; LIHC cis rs600806 0.778 rs2043059 chr1:109991009 C/A cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.61 -0.38 2.77e-13 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25525087 chr17:17743565 NA -0.4 -6.09 -0.31 3e-9 Cognitive function; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg18697163 chr20:60738480 SS18L1 0.47 6.72 0.34 7.66e-11 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs965469 1.000 rs6037579 chr20:3347980 G/A cg25506879 chr20:3388711 C20orf194 -0.56 -6.62 -0.34 1.41e-10 IFN-related cytopenia; LIHC cis rs1707322 1.000 rs10789479 chr1:46352500 T/C cg03146154 chr1:46216737 IPP 0.48 7.56 0.38 3.83e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs853679 0.517 rs17774663 chr6:28120898 G/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1552244 0.882 rs3732966 chr3:10015740 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC trans rs8073060 0.518 rs225285 chr17:33931084 G/C cg19694781 chr19:47549865 TMEM160 -0.91 -10.15 -0.48 2.5e-21 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs600806 0.778 rs2039694 chr1:109991700 A/G cg16275483 chr1:110013120 SYPL2 -0.47 -5.83 -0.3 1.27e-8 Intelligence (multi-trait analysis); LIHC cis rs202629 1 rs202629 chr22:41849975 C/T cg17554472 chr22:41940697 POLR3H 0.55 6.23 0.32 1.38e-9 Cannabis dependence symptom count; LIHC cis rs4843747 0.749 rs13333619 chr16:88072076 C/T cg07560587 chr16:88016574 BANP 0.43 6.86 0.35 3.31e-11 Menopause (age at onset); LIHC trans rs1814175 0.781 rs12286395 chr11:49954062 C/G cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs2629540 0.508 rs12217633 chr10:126533872 A/G cg08799069 chr10:126477246 METTL10 -0.44 -6.77 -0.34 5.65e-11 Cocaine dependence; LIHC cis rs1401999 1.000 rs6443926 chr3:183706630 A/C cg01324343 chr3:183735012 ABCC5 0.76 12.92 0.57 2.27e-31 Anterior chamber depth; LIHC cis rs1059312 0.966 rs2291349 chr12:129284248 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -14.46 -0.62 2.58e-37 Systemic lupus erythematosus; LIHC cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg00684032 chr4:1343700 KIAA1530 0.4 6.82 0.35 4.22e-11 Obesity-related traits; LIHC cis rs11792861 0.816 rs28361186 chr9:111704064 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.83 0.43 5.58e-17 Menarche (age at onset); LIHC cis rs6964587 1.000 rs13239875 chr7:91716104 G/A cg17063962 chr7:91808500 NA 1.0 19.05 0.72 1.18e-55 Breast cancer; LIHC cis rs8044995 0.501 rs7189887 chr16:68353915 C/T cg09835421 chr16:68378352 PRMT7 -0.88 -10.26 -0.48 1.07e-21 Schizophrenia; LIHC cis rs10791097 0.720 rs6590516 chr11:130733393 G/T cg12179176 chr11:130786555 SNX19 0.8 12.89 0.57 3.02e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7959452 0.535 rs7133487 chr12:69774377 G/A cg20891283 chr12:69753455 YEATS4 0.9 19.46 0.72 2.57e-57 Blood protein levels; LIHC cis rs6504950 0.800 rs8065361 chr17:53008853 A/T cg10237252 chr17:52977213 TOM1L1 -0.34 -5.99 -0.31 5.22e-9 Breast cancer; LIHC trans rs7178375 1.000 rs35162264 chr15:31200683 T/A cg04373760 chr16:53404718 NA 0.61 7.96 0.4 2.63e-14 Hypertriglyceridemia; LIHC cis rs2153535 0.580 rs1119689 chr6:8460754 C/G cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs13336428 0.730 rs3946124 chr16:1525779 A/G cg07835181 chr16:1525278 CLCN7 -0.68 -12.01 -0.54 5.72e-28 Bone mineral density; LIHC cis rs9814567 1.000 rs9863786 chr3:134247203 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4253772 0.591 rs6007747 chr22:46657261 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.73 6.63 0.34 1.35e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg00343986 chr7:65444356 GUSB 0.45 6.34 0.32 7.19e-10 Aortic root size; LIHC cis rs2274273 0.837 rs10141483 chr14:55786871 T/C cg01864836 chr14:55583639 NA -0.4 -7.45 -0.37 7.51e-13 Protein biomarker; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg12026394 chr9:100745975 ANP32B 0.5 6.56 0.33 1.96e-10 Hepatitis; LIHC cis rs7677751 0.806 rs6554163 chr4:55102559 A/T cg17187183 chr4:55093834 PDGFRA 0.67 8.91 0.43 3.13e-17 Corneal astigmatism; LIHC trans rs1005277 0.579 rs1780139 chr10:38503018 C/T cg23533926 chr12:111358616 MYL2 -0.35 -6.7 -0.34 8.54e-11 Extrinsic epigenetic age acceleration; LIHC cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg18357526 chr6:26021779 HIST1H4A -0.43 -6.03 -0.31 4.24e-9 Blood metabolite levels; LIHC cis rs12101261 1.000 rs17111346 chr14:81452172 G/A cg06600135 chr14:81408086 NA 0.36 6.25 0.32 1.21e-9 Graves' disease; LIHC cis rs611744 0.967 rs686265 chr8:109199763 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs9311474 0.629 rs13081028 chr3:52555316 G/A cg18404041 chr3:52824283 ITIH1 -0.45 -7.4 -0.37 1.04e-12 Electroencephalogram traits; LIHC cis rs9325144 0.555 rs4882284 chr12:38710459 C/T cg26384229 chr12:38710491 ALG10B -0.57 -7.92 -0.39 3.42e-14 Morning vs. evening chronotype; LIHC cis rs1003719 0.715 rs8130643 chr21:38551715 T/A cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.99 -0.51 2.91e-24 Eye color traits; LIHC cis rs9633740 1.000 rs10749609 chr10:82249752 G/A cg01528321 chr10:82214614 TSPAN14 0.61 8.76 0.43 8.97e-17 Post bronchodilator FEV1; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg18576335 chr17:8110165 AURKB 0.41 6.18 0.32 1.78e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs16828019 0.852 rs2300649 chr1:41569203 T/C cg03387723 chr1:41708464 SCMH1 -0.41 -6.76 -0.34 5.83e-11 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.541 rs9379207 chr6:8458186 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs5753618 0.539 rs695438 chr22:31811876 G/C cg02404636 chr22:31891804 SFI1 0.33 5.73 0.3 2.18e-8 Colorectal cancer; LIHC cis rs7937682 0.924 rs4630327 chr11:111539327 C/T cg09085632 chr11:111637200 PPP2R1B 1.03 13.13 0.58 3.46e-32 Primary sclerosing cholangitis; LIHC cis rs9560113 1.000 rs4773379 chr13:112176088 G/C cg14154082 chr13:112174009 NA 0.29 6.15 0.32 2.2e-9 Menarche (age at onset); LIHC cis rs2067615 0.524 rs4275715 chr12:107062246 C/T cg15890332 chr12:107067104 RFX4 0.27 6.36 0.33 6.32e-10 Heart rate; LIHC cis rs56235845 0.694 rs4532376 chr5:176774403 G/A cg06060754 chr5:176797920 RGS14 0.47 6.72 0.34 7.41e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs67460515 0.529 rs11712713 chr3:160852471 A/G cg17135325 chr3:160939158 NMD3 0.55 7.71 0.38 1.36e-13 Parkinson's disease; LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg04632378 chr13:21900426 NA 0.39 6.49 0.33 3.09e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs174601 0.861 rs174580 chr11:61606642 A/G cg27386326 chr11:61587980 NA 0.68 14.61 0.62 6.93e-38 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs875971 0.862 rs2420173 chr7:65645399 A/T cg18876405 chr7:65276391 NA -0.36 -6.37 -0.33 5.93e-10 Aortic root size; LIHC cis rs12586317 0.620 rs7147571 chr14:35530236 T/C cg05294307 chr14:35346193 BAZ1A -0.46 -6.65 -0.34 1.17e-10 Psoriasis; LIHC cis rs11098499 0.954 rs878373 chr4:120237484 A/T cg09307838 chr4:120376055 NA 0.75 11.41 0.52 9.41e-26 Corneal astigmatism; LIHC cis rs6964587 0.967 rs1978061 chr7:91779242 G/A cg17063962 chr7:91808500 NA 1.06 22.62 0.77 6.65e-70 Breast cancer; LIHC cis rs12413816 0.963 rs12359348 chr10:13765950 C/T cg16485048 chr10:13749193 FRMD4A -0.58 -8.8 -0.43 6.68e-17 Red cell distribution width; LIHC cis rs4665809 0.549 rs7577896 chr2:26524493 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.08 12.36 0.56 2.95e-29 Gut microbiome composition (summer); LIHC cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg08132940 chr7:1081526 C7orf50 -0.79 -6.72 -0.34 7.83e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.11 0.52 1.04e-24 Platelet count; LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg11060661 chr22:24314208 DDT;DDTL 0.59 10.25 0.48 1.11e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2635047 0.935 rs2635050 chr18:44664131 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.46 6.14 0.31 2.32e-9 Educational attainment; LIHC cis rs72781680 0.752 rs72796110 chr2:23905658 T/A cg08917208 chr2:24149416 ATAD2B 0.98 8.06 0.4 1.29e-14 Lymphocyte counts; LIHC cis rs4925386 0.840 rs8124907 chr20:60913127 A/G cg06026331 chr20:60912101 LAMA5 0.62 9.22 0.45 3.13e-18 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC trans rs7777677 0.925 rs6956269 chr7:142369136 T/G cg21680980 chr1:221069572 NA -0.48 -6.08 -0.31 3.27e-9 Alcoholic chronic pancreatitis; LIHC cis rs903552 0.800 rs28470883 chr15:102000824 G/A cg19295451 chr15:102010161 PCSK6 -0.46 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC cis rs1448094 0.512 rs4362214 chr12:86245145 C/T cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC trans rs11088226 0.645 rs2409457 chr21:33929895 T/C cg09050820 chr6:167586206 TCP10L2 0.85 13.42 0.59 2.73e-33 Gastritis; LIHC cis rs757081 0.667 rs34724588 chr11:17137581 T/C cg15432903 chr11:17409602 KCNJ11 -0.42 -5.91 -0.3 8.46e-9 Systolic blood pressure; LIHC cis rs9486719 0.895 rs4486019 chr6:96883814 T/C cg06623918 chr6:96969491 KIAA0776 -0.73 -7.27 -0.37 2.41e-12 Migraine;Coronary artery disease; LIHC cis rs7511006 0.859 rs7292228 chr22:50649560 C/G cg07895657 chr22:50616420 PANX2 -0.37 -6.5 -0.33 2.89e-10 Obesity-related traits; LIHC cis rs5769707 0.521 rs5770633 chr22:50062427 G/A cg01652190 chr22:50026171 C22orf34 -0.29 -6.3 -0.32 9.2e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs847851 0.569 rs3800439 chr6:34961406 T/C cg13137465 chr6:34857473 ANKS1A 0.67 7.53 0.38 4.57e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg23758822 chr17:41437982 NA 0.94 17.96 0.7 2.83e-51 Menopause (age at onset); LIHC cis rs9640161 0.742 rs11767726 chr7:150018096 A/C cg17279839 chr7:150038598 RARRES2 -0.48 -10.17 -0.48 2.18e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs1997103 1.000 rs2331065 chr7:55408392 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs853679 0.517 rs9380056 chr6:28104476 C/T cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs7216064 1.000 rs9915108 chr17:65874463 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs3020736 0.500 rs5996111 chr22:42493902 C/T cg05082376 chr22:42548792 NA 0.39 5.71 0.3 2.41e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg26116260 chr4:7069785 GRPEL1 0.96 17.76 0.69 1.79e-50 Monocyte percentage of white cells; LIHC cis rs6545883 0.929 rs1186711 chr2:61688505 T/C cg14146966 chr2:61757674 XPO1 0.45 7.58 0.38 3.27e-13 Tuberculosis; LIHC trans rs6952808 0.692 rs6950627 chr7:2086672 C/T cg04565464 chr8:145669602 NFKBIL2 0.38 6.31 0.32 8.4e-10 Bipolar disorder and schizophrenia; LIHC cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg01646665 chr1:156251436 TMEM79;SMG5 -0.3 -5.76 -0.3 1.84e-8 Tonsillectomy; LIHC cis rs13108904 0.539 rs13141992 chr4:1340765 C/T cg13395646 chr4:1353034 KIAA1530 -0.86 -13.02 -0.58 9.33e-32 Obesity-related traits; LIHC cis rs7487075 0.619 rs6582645 chr12:46805144 C/T cg23829395 chr12:46796953 NA 0.36 6.29 0.32 9.45e-10 Itch intensity from mosquito bite; LIHC cis rs7607369 0.782 rs639913 chr2:219365971 A/C cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs870825 0.550 rs10000507 chr4:185619281 C/T cg04058563 chr4:185651563 MLF1IP 0.65 6.94 0.35 2.01e-11 Blood protein levels; LIHC cis rs35110281 0.626 rs162368 chr21:44934767 G/A cg04455712 chr21:45112962 RRP1B 0.42 7.17 0.36 4.75e-12 Mean corpuscular volume; LIHC cis rs311392 0.525 rs311422 chr8:55105483 T/C cg20636351 chr8:55087400 NA -0.32 -6.54 -0.33 2.22e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg19500098 chr13:21900506 NA 0.4 6.49 0.33 3.06e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11628318 0.515 rs9324049 chr14:103096352 T/C cg12046867 chr14:103022105 NA -0.37 -5.72 -0.3 2.28e-8 Platelet count; LIHC cis rs2455799 0.552 rs2470519 chr3:15762847 G/A cg12698662 chr3:15914712 MIR563 -0.39 -7.27 -0.37 2.46e-12 Mean platelet volume; LIHC trans rs75804782 0.641 rs11885523 chr2:239344263 G/A cg01134436 chr17:81009848 B3GNTL1 0.8 6.97 0.35 1.59e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs8114671 0.836 rs2104083 chr20:33649133 G/A cg07148914 chr20:33460835 GGT7 -0.56 -8.45 -0.42 8.7e-16 Height; LIHC cis rs7095607 0.538 rs2634708 chr10:69920013 C/A cg18986048 chr10:69913749 MYPN 0.49 7.33 0.37 1.65e-12 Lung function (FVC); LIHC cis rs477692 0.673 rs1078847 chr10:131352115 T/C cg19680672 chr10:131412579 MGMT -0.39 -5.92 -0.3 8.01e-9 Response to temozolomide; LIHC cis rs2108622 0.727 rs7253873 chr19:15980900 A/G cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs2576037 0.583 rs512699 chr18:44374681 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.42 6.08 0.31 3.3e-9 Personality dimensions; LIHC cis rs2191566 0.747 rs4803667 chr19:44533604 T/C cg18700516 chr19:44507157 ZNF230 -0.37 -6.18 -0.32 1.83e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs2032447 0.531 rs428469 chr6:25898624 G/A cg12310025 chr6:25882481 NA -1.08 -13.82 -0.6 8.26e-35 Intelligence (multi-trait analysis); LIHC cis rs10744422 1.000 rs897386 chr12:123341289 A/C cg22842854 chr12:123319900 HIP1R -0.68 -8.81 -0.43 6.29e-17 Schizophrenia; LIHC cis rs4699052 0.928 rs4456958 chr4:104215332 A/G cg16532752 chr4:104119610 CENPE -0.4 -6.37 -0.33 6.09e-10 Testicular germ cell tumor; LIHC cis rs4699052 0.928 rs2169511 chr4:104192580 G/A cg16532752 chr4:104119610 CENPE -0.4 -6.35 -0.32 6.81e-10 Testicular germ cell tumor; LIHC cis rs11792861 0.926 rs56899598 chr9:111867271 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.6 0.42 2.91e-16 Menarche (age at onset); LIHC cis rs992157 0.835 rs6707559 chr2:219142773 C/T cg00012203 chr2:219082015 ARPC2 0.83 13.45 0.59 2.22e-33 Colorectal cancer; LIHC cis rs4713118 0.868 rs2893928 chr6:27738430 C/A cg20933634 chr6:27740509 NA 0.47 6.04 0.31 3.91e-9 Parkinson's disease; LIHC cis rs6782228 0.675 rs4857918 chr3:128383960 T/C cg16766828 chr3:128327626 NA -0.43 -6.8 -0.35 4.66e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs10540 0.730 rs12789735 chr11:518509 G/A cg03352830 chr11:487213 PTDSS2 0.79 6.39 0.33 5.48e-10 Body mass index; LIHC cis rs9818758 0.607 rs11552724 chr3:49156473 C/G cg06212747 chr3:49208901 KLHDC8B -0.66 -5.81 -0.3 1.45e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs17784882 0.524 rs7433300 chr3:47120640 G/A cg16586182 chr3:47516702 SCAP -0.48 -8.48 -0.42 6.9e-16 QT interval; LIHC cis rs2625529 0.667 rs16956381 chr15:72193237 A/C cg16672083 chr15:72433130 SENP8 -0.31 -5.77 -0.3 1.73e-8 Red blood cell count; LIHC cis rs5769765 0.862 rs9616385 chr22:50313124 C/T cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg07061783 chr6:25882402 NA -0.5 -6.39 -0.33 5.49e-10 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.541 rs9505456 chr6:8479001 T/C cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs2404602 0.598 rs11634019 chr15:76634680 A/G cg03037974 chr15:76606532 NA -0.69 -11.33 -0.52 1.74e-25 Blood metabolite levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg25025968 chr11:4116056 RRM1 -0.41 -7.04 -0.36 1.09e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2228479 0.717 rs17233678 chr16:89809962 T/C cg00800038 chr16:89945340 TCF25 -0.61 -8.89 -0.43 3.56e-17 Skin colour saturation; LIHC cis rs7712401 0.525 rs193541 chr5:122253304 C/T cg18764291 chr5:122110994 SNX2 0.41 6.86 0.35 3.22e-11 Mean platelet volume; LIHC cis rs7107174 0.901 rs2511162 chr11:77927101 A/G cg02023728 chr11:77925099 USP35 0.49 9.42 0.45 6.86e-19 Testicular germ cell tumor; LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg06138931 chr13:21896616 NA 0.57 9.91 0.47 1.67e-20 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2303745 0.589 rs10401700 chr19:17397700 A/C cg02221750 chr19:17393354 ANKLE1 -0.42 -6.17 -0.32 1.98e-9 Systemic lupus erythematosus; LIHC cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg02359409 chr6:42947317 PEX6 -0.47 -6.58 -0.34 1.76e-10 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs61931739 0.517 rs11053067 chr12:34191391 T/C cg26384229 chr12:38710491 ALG10B 0.6 7.67 0.38 1.83e-13 Morning vs. evening chronotype; LIHC cis rs17685 0.753 rs4732542 chr7:75663203 A/G cg01364799 chr7:75623366 TMEM120A -0.48 -7.53 -0.38 4.68e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4908768 0.657 rs6693466 chr1:8817938 C/T cg20416874 chr1:8611966 RERE 0.46 6.59 0.34 1.64e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs875971 0.658 rs432667 chr7:65514633 A/G cg18876405 chr7:65276391 NA 0.42 7.39 0.37 1.16e-12 Aortic root size; LIHC cis rs72829446 0.530 rs9906913 chr17:7411360 G/A cg02795151 chr17:7402630 POLR2A 0.54 6.4 0.33 5.07e-10 Androgen levels; LIHC cis rs35110281 0.774 rs162404 chr21:44963264 G/A cg01579765 chr21:45077557 HSF2BP -0.32 -6.05 -0.31 3.75e-9 Mean corpuscular volume; LIHC cis rs10823500 0.777 rs10762348 chr10:71952322 C/A cg04118878 chr10:71993077 PPA1 0.58 6.06 0.31 3.56e-9 Blood protein levels; LIHC cis rs7666738 0.830 rs1813642 chr4:98852225 G/A cg05340658 chr4:99064831 C4orf37 0.67 12.44 0.56 1.45e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs57590327 0.679 rs13082609 chr3:81642131 A/G cg07356753 chr3:81810745 GBE1 -0.5 -6.79 -0.34 4.92e-11 Extraversion; LIHC cis rs9916302 0.904 rs8079560 chr17:37497661 C/T cg07936489 chr17:37558343 FBXL20 0.84 13.6 0.59 5.67e-34 Glomerular filtration rate (creatinine); LIHC cis rs6141600 0.540 rs761312 chr20:34687809 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.63 -0.34 1.33e-10 Height;Hip circumference; LIHC trans rs35110281 0.837 rs12627667 chr21:45071396 A/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.44 6.15 0.32 2.13e-9 Mean corpuscular volume; LIHC cis rs4700695 0.841 rs152994 chr5:65262989 A/G cg21114390 chr5:65439923 SFRS12 0.44 5.72 0.3 2.31e-8 Facial morphology (factor 19); LIHC cis rs709400 0.663 rs7158822 chr14:103887868 C/T cg26031613 chr14:104095156 KLC1 0.73 9.92 0.47 1.53e-20 Body mass index; LIHC cis rs7131987 0.834 rs11050167 chr12:29426387 C/T cg05697976 chr12:29376483 FAR2 0.3 5.79 0.3 1.57e-8 QT interval; LIHC cis rs882732 1.000 rs10149354 chr14:95038368 C/T cg14866387 chr14:95027382 SERPINA4 -0.46 -6.25 -0.32 1.2e-9 Blood protein levels; LIHC cis rs1018836 0.923 rs6986001 chr8:91650205 T/C cg16814680 chr8:91681699 NA -0.64 -9.93 -0.47 1.4e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1494950 0.661 rs2702521 chr4:15017141 C/T cg12377275 chr4:15005593 CPEB2 -0.79 -7.13 -0.36 5.96e-12 Political ideology; LIHC cis rs8081395 0.932 rs2777885 chr17:57830473 C/A cg13753209 chr17:57696993 CLTC -0.48 -7.28 -0.37 2.35e-12 White blood cell count; LIHC cis rs2645694 0.911 rs2703147 chr4:77831307 C/T cg03477792 chr4:77819574 ANKRD56 0.48 6.51 0.33 2.63e-10 Emphysema distribution in smoking; LIHC cis rs1165668 0.785 rs2070908 chr12:104324182 C/G cg21863207 chr12:104234989 NT5DC3 -0.44 -7.47 -0.37 6.76e-13 Coronary heart disease (SNP X SNP interaction); LIHC cis rs2292096 0.929 rs12729842 chr1:200761806 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.46 -6.13 -0.31 2.38e-9 Epilepsy; LIHC cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs1215050 0.765 rs6852699 chr4:98767505 T/C cg05340658 chr4:99064831 C4orf37 0.4 5.88 0.3 9.88e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.4 -0.37 1.04e-12 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg16822855 chr3:40428330 ENTPD3 0.33 5.9 0.3 8.89e-9 Renal cell carcinoma; LIHC cis rs2991971 1.000 rs2991971 chr1:46012748 C/G cg03146154 chr1:46216737 IPP -0.39 -5.93 -0.31 7.45e-9 High light scatter reticulocyte count; LIHC cis rs8103278 0.507 rs16939 chr19:46276056 C/A cg02376097 chr19:46275166 DMPK 0.54 9.5 0.46 3.73e-19 Coronary artery disease; LIHC cis rs208520 0.526 rs7775830 chr6:66755249 A/G cg07460842 chr6:66804631 NA 0.84 15.0 0.63 2.02e-39 Exhaled nitric oxide output; LIHC cis rs875971 1.000 rs7789768 chr7:65938980 A/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs2370759 0.898 rs113412621 chr10:32579306 C/T cg18270830 chr10:32634957 EPC1 0.53 6.48 0.33 3.19e-10 Sexual dysfunction (female); LIHC cis rs6732160 0.691 rs1960233 chr2:73421378 A/G cg24220031 chr2:73402428 NA -0.27 -5.9 -0.3 8.62e-9 Intelligence (multi-trait analysis); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11488864 chr4:8379238 ACOX3 0.45 6.31 0.32 8.8e-10 Bilirubin levels; LIHC trans rs78049276 0.736 rs73855814 chr4:148397751 G/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.57 -7.44 -0.37 8.18e-13 Pulse pressure; LIHC cis rs7618915 1.000 rs34569561 chr3:52287293 T/C cg18404041 chr3:52824283 ITIH1 -0.38 -5.75 -0.3 1.98e-8 Bipolar disorder; LIHC cis rs3770081 0.793 rs74743393 chr2:86227421 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -8.42 -0.41 1.03e-15 Facial emotion recognition (sad faces); LIHC cis rs10489202 1.000 rs1846416 chr1:167905411 G/A cg24449463 chr1:168025552 DCAF6 -0.53 -6.48 -0.33 3.12e-10 Schizophrenia; LIHC cis rs507080 0.733 rs488141 chr11:118571168 A/G cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs7258015 0.865 rs1058154 chr19:10446897 C/A cg13981319 chr19:10446556 ICAM3 0.45 6.57 0.33 1.9e-10 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs6545883 0.894 rs35292974 chr2:61522047 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.38 -0.37 1.25e-12 Tuberculosis; LIHC cis rs67460515 0.892 rs11929238 chr3:161045937 A/T cg03342759 chr3:160939853 NMD3 -0.62 -9.26 -0.45 2.31e-18 Parkinson's disease; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.24 0.55 7.84e-29 Prudent dietary pattern; LIHC cis rs694739 0.894 rs887314 chr11:64053157 T/G cg23796481 chr11:64053134 BAD;GPR137 0.6 8.19 0.4 5.36e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs561341 1.000 rs72823789 chr17:30284084 G/A cg20587970 chr11:113659929 NA -1.46 -11.99 -0.54 6.92e-28 Hip circumference adjusted for BMI; LIHC cis rs9596863 0.950 rs6561749 chr13:54435195 G/C ch.13.53330881F chr13:54432880 NA -0.45 -6.46 -0.33 3.68e-10 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs10751667 0.666 rs7395402 chr11:950293 A/G ch.11.42038R chr11:967971 AP2A2 -0.56 -10.16 -0.48 2.37e-21 Alzheimer's disease (late onset); LIHC cis rs473651 0.935 rs35080527 chr2:239351387 T/C cg21699342 chr2:239360505 ASB1 0.36 7.02 0.35 1.22e-11 Multiple system atrophy; LIHC cis rs6089829 0.855 rs6062781 chr20:61667128 G/A cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg19774624 chr17:42201019 HDAC5 -0.67 -10.15 -0.48 2.47e-21 Total body bone mineral density; LIHC cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg06481639 chr22:41940642 POLR3H -0.65 -5.78 -0.3 1.68e-8 Vitiligo; LIHC cis rs600806 0.888 rs461200 chr1:109855404 G/A cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.87 -0.3 1.05e-8 Intelligence (multi-trait analysis); LIHC cis rs933688 0.502 rs4916858 chr5:90601290 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 -0.36 -6.32 -0.32 8.01e-10 Smoking behavior; LIHC cis rs35110281 0.743 rs230640 chr21:44914815 A/T cg01579765 chr21:45077557 HSF2BP 0.31 5.73 0.3 2.21e-8 Mean corpuscular volume; LIHC cis rs6586163 0.872 rs7069841 chr10:90741955 T/C cg03111039 chr10:90751583 FAS;ACTA2 -0.53 -7.78 -0.39 8.86e-14 Chronic lymphocytic leukemia; LIHC cis rs780096 0.565 rs10169261 chr2:27727314 C/T cg21747090 chr2:27597821 SNX17 -0.46 -6.75 -0.34 6.3e-11 Total body bone mineral density; LIHC cis rs1707322 1.000 rs10890370 chr1:46389217 C/T cg03146154 chr1:46216737 IPP 0.48 7.59 0.38 3.02e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7777484 0.534 rs2533888 chr7:2831083 T/C cg18446336 chr7:2847575 GNA12 -0.33 -6.46 -0.33 3.56e-10 Height; LIHC cis rs2153535 0.580 rs9379210 chr6:8461928 C/G cg07606381 chr6:8435919 SLC35B3 0.8 11.8 0.54 3.57e-27 Motion sickness; LIHC cis rs3743266 0.507 rs11637887 chr15:60765216 C/T cg22293140 chr15:60689852 ANXA2 -0.62 -5.86 -0.3 1.08e-8 Menarche (age at onset); LIHC cis rs2540917 0.594 rs56180823 chr2:60662004 A/G cg00543073 chr2:60773386 BCL11A -0.32 -6.4 -0.33 5.12e-10 Mean corpuscular volume; LIHC cis rs2836950 0.565 rs8134214 chr21:40542367 A/C cg11890956 chr21:40555474 PSMG1 -0.49 -8.15 -0.4 6.76e-15 Menarche (age at onset); LIHC cis rs1801251 0.896 rs4973561 chr2:233687337 C/G cg08000102 chr2:233561755 GIGYF2 -0.74 -10.78 -0.5 1.56e-23 Coronary artery disease; LIHC cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg23758822 chr17:41437982 NA 0.94 18.02 0.7 1.57e-51 Menopause (age at onset); LIHC cis rs2758596 0.826 rs2758602 chr1:156198232 T/G cg24450063 chr1:156163899 SLC25A44 0.99 10.48 0.49 1.76e-22 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs7395581 0.918 rs3847502 chr11:47333685 C/A cg26139080 chr11:47293733 MADD -0.5 -8.45 -0.42 8.46e-16 HDL cholesterol; LIHC cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg10896456 chr17:42255109 ASB16;C17orf65 0.47 8.75 0.43 9.66e-17 Total body bone mineral density; LIHC cis rs6860806 0.507 rs272872 chr5:131675864 C/T cg24060327 chr5:131705240 SLC22A5 0.76 11.91 0.54 1.36e-27 Breast cancer; LIHC cis rs1008375 0.966 rs6833808 chr4:17652526 T/A cg15017067 chr4:17643749 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg21724239 chr8:58056113 NA -0.53 -6.7 -0.34 8.49e-11 Developmental language disorder (linguistic errors); LIHC cis rs10540 1.000 rs71487296 chr11:500282 G/A cg03352830 chr11:487213 PTDSS2 0.8 6.58 0.34 1.76e-10 Body mass index; LIHC trans rs17711722 0.528 rs73138179 chr7:65294482 G/T cg10756647 chr7:56101905 PSPH -0.46 -6.8 -0.35 4.82e-11 Calcium levels; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg27211696 chr2:191398769 TMEM194B 0.7 11.41 0.53 8.88e-26 Pulse pressure; LIHC cis rs4845570 0.850 rs4618976 chr1:151766588 A/G cg07092448 chr1:151763213 TDRKH 0.69 7.42 0.37 9.54e-13 Coronary artery disease; LIHC cis rs2839186 0.903 rs61182475 chr21:47707050 T/A cg09417038 chr21:47716443 C21orf57 -0.53 -7.89 -0.39 4.05e-14 Testicular germ cell tumor; LIHC cis rs2228479 0.717 rs17233678 chr16:89809962 T/C cg04013166 chr16:89971882 TCF25 0.49 6.08 0.31 3.24e-9 Skin colour saturation; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.71 -0.3 2.45e-8 Total body bone mineral density; LIHC cis rs1873147 0.569 rs12593573 chr15:63309919 G/A cg21584241 chr15:63341463 TPM1 0.44 6.38 0.33 5.9e-10 Orofacial clefts; LIHC cis rs986417 0.901 rs7150630 chr14:61019458 T/A cg27398547 chr14:60952738 C14orf39 0.71 7.93 0.39 3.1e-14 Gut microbiota (bacterial taxa); LIHC cis rs67478160 0.619 rs8018062 chr14:104281954 C/T cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.19 -0.36 4.24e-12 Schizophrenia; LIHC cis rs2576037 0.526 rs4258717 chr18:44456954 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.56 0.5 9.43e-23 Personality dimensions; LIHC cis rs1707322 1.000 rs6429580 chr1:46275648 A/G cg03146154 chr1:46216737 IPP 0.47 7.56 0.38 3.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg14004847 chr7:1930337 MAD1L1 0.55 7.97 0.4 2.39e-14 Bipolar disorder and schizophrenia; LIHC cis rs4665809 1.000 rs1470097 chr2:26312840 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.87 -0.43 4.13e-17 Gut microbiome composition (summer); LIHC cis rs2637266 0.663 rs846581 chr10:78497984 C/T cg18941641 chr10:78392320 NA 0.27 5.83 0.3 1.3e-8 Pulmonary function; LIHC cis rs589448 0.538 rs622656 chr12:69753595 C/T cg20891283 chr12:69753455 YEATS4 0.84 16.35 0.66 8.71e-45 Cerebrospinal fluid biomarker levels; LIHC cis rs858239 0.633 rs858300 chr7:23244631 A/G cg18081818 chr7:23246105 NA -0.46 -7.08 -0.36 8.14e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs2760061 0.819 rs1745417 chr1:228204279 C/T cg01200585 chr1:228362443 C1orf69 0.41 6.3 0.32 8.98e-10 Diastolic blood pressure; LIHC cis rs7107174 0.892 rs4945265 chr11:78027458 G/A cg02023728 chr11:77925099 USP35 0.52 9.83 0.47 2.9e-20 Testicular germ cell tumor; LIHC cis rs11792861 0.816 rs72607157 chr9:111748001 T/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.75 0.43 1.01e-16 Menarche (age at onset); LIHC cis rs9322817 0.691 rs2499663 chr6:105300570 A/G cg02098413 chr6:105308735 HACE1 -0.43 -7.92 -0.39 3.37e-14 Thyroid stimulating hormone; LIHC cis rs60871478 1.000 rs4721124 chr7:823761 T/C cg27478167 chr7:817139 HEATR2 -0.4 -5.77 -0.3 1.82e-8 Cerebrospinal P-tau181p levels; LIHC cis rs17685 0.712 rs6953342 chr7:75776753 T/C cg16684958 chr7:75615977 POR 0.4 6.57 0.33 1.87e-10 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg07781247 chr5:93954443 ANKRD32;C5orf36 0.39 6.26 0.32 1.17e-9 Migraine with aura; LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg02132458 chr4:57333267 SRP72 -0.57 -6.2 -0.32 1.64e-9 Bronchial neuroendocrine tumor; LIHC cis rs709400 1.000 rs861539 chr14:104165753 G/A cg26031613 chr14:104095156 KLC1 1.03 12.96 0.57 1.56e-31 Body mass index; LIHC cis rs2073499 0.873 rs6446202 chr3:50219991 C/G cg03645007 chr3:50255295 SLC38A3 0.42 5.82 0.3 1.35e-8 Schizophrenia; LIHC cis rs17826219 0.568 rs9903854 chr17:29153998 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.76 0.34 5.89e-11 Body mass index; LIHC cis rs425277 0.583 rs12059660 chr1:2041461 C/T cg04315214 chr1:2043799 PRKCZ 0.36 5.78 0.3 1.65e-8 Height; LIHC cis rs2066819 1.000 rs2066819 chr12:56750204 C/T cg26714650 chr12:56694279 CS -1.35 -12.74 -0.57 1.09e-30 Psoriasis vulgaris; LIHC cis rs8114671 0.562 rs6088647 chr20:33505997 T/C cg07148914 chr20:33460835 GGT7 0.66 10.12 0.48 3.16e-21 Height; LIHC cis rs2067615 0.579 rs7486905 chr12:107160169 G/A cg15890332 chr12:107067104 RFX4 0.26 6.03 0.31 4.27e-9 Heart rate; LIHC cis rs8058578 1.000 rs6565201 chr16:30747191 C/T cg02466173 chr16:30829666 NA -0.43 -6.79 -0.34 4.95e-11 Multiple myeloma; LIHC cis rs6582630 0.537 rs1851124 chr12:38516404 G/A cg13010199 chr12:38710504 ALG10B 0.46 6.22 0.32 1.42e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.15 -0.32 2.2e-9 Total body bone mineral density; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs11711311 0.712 rs6764048 chr3:113332859 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 0.38 6.59 0.34 1.69e-10 IgG glycosylation; LIHC cis rs1538970 0.924 rs11211111 chr1:45908782 C/T cg24296786 chr1:45957014 TESK2 -0.51 -7.42 -0.37 9.41e-13 Platelet count; LIHC cis rs780096 0.546 rs8179225 chr2:27737181 A/G cg22903471 chr2:27725779 GCKR -0.53 -8.93 -0.43 2.61e-17 Total body bone mineral density; LIHC trans rs800082 0.698 rs1178943 chr3:144391772 T/G cg24215973 chr2:240111563 HDAC4 -0.63 -9.42 -0.45 6.94e-19 Smoking behavior; LIHC cis rs2243480 0.901 rs778693 chr7:65872345 T/G cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC cis rs853679 0.517 rs12174753 chr6:28042465 C/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs765787 0.530 rs28733848 chr15:45516047 C/T cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC trans rs61931739 0.500 rs7137392 chr12:34447074 T/C cg26384229 chr12:38710491 ALG10B 0.64 8.06 0.4 1.31e-14 Morning vs. evening chronotype; LIHC cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.98 0.31 5.55e-9 Schizophrenia; LIHC cis rs16828019 0.777 rs10489521 chr1:41508490 C/T cg03387723 chr1:41708464 SCMH1 -0.41 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs9926296 0.607 rs2079672 chr16:89884917 A/G cg04287289 chr16:89883240 FANCA -0.56 -9.75 -0.47 5.66e-20 Vitiligo; LIHC cis rs950169 1.000 rs12915234 chr15:84758301 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs9314323 0.592 rs12165 chr8:26269412 C/T cg13160058 chr8:26243215 BNIP3L -0.33 -6.43 -0.33 4.18e-10 Red cell distribution width; LIHC cis rs2404602 0.647 rs11634266 chr15:77093461 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.56 -0.46 2.47e-19 Blood metabolite levels; LIHC cis rs8180040 0.966 rs3736177 chr3:47451411 C/T cg27129171 chr3:47204927 SETD2 -0.57 -9.54 -0.46 2.71e-19 Colorectal cancer; LIHC cis rs2932538 0.922 rs12406906 chr1:113117900 G/T cg22162597 chr1:113214053 CAPZA1 -0.68 -10.71 -0.5 2.82e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs4423214 1.000 rs4944957 chr11:71168035 C/T cg05163923 chr11:71159392 DHCR7 -0.82 -12.51 -0.56 8.16e-30 Vitamin D levels; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg26338869 chr17:61819248 STRADA -0.6 -8.78 -0.43 7.97e-17 Prudent dietary pattern; LIHC cis rs7927771 0.931 rs12361256 chr11:47910823 A/C cg20307385 chr11:47447363 PSMC3 -0.48 -6.32 -0.32 8.05e-10 Subjective well-being; LIHC cis rs2228479 0.850 rs11076623 chr16:89844120 G/T cg03721293 chr16:90014378 DEF8 0.36 5.72 0.3 2.33e-8 Skin colour saturation; LIHC cis rs1062177 0.826 rs1549920 chr5:151140844 A/T cg00977110 chr5:151150581 G3BP1 0.56 7.0 0.35 1.37e-11 Preschool internalizing problems; LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.45e-13 Prudent dietary pattern; LIHC cis rs6545883 0.826 rs777591 chr2:61417617 A/G cg15711740 chr2:61764176 XPO1 -0.41 -5.71 -0.3 2.43e-8 Tuberculosis; LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.36 -5.89 -0.3 9.19e-9 Height; LIHC cis rs7208859 0.673 rs9889968 chr17:29220128 C/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs5769765 1.000 rs8184990 chr22:50273174 A/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC trans rs11153056 0.500 rs17068076 chr6:107537007 T/C cg12119218 chr10:70287206 SLC25A16 -0.45 -6.13 -0.31 2.39e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs9902453 0.833 rs7216631 chr17:28495112 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.92 0.47 1.48e-20 Coffee consumption (cups per day); LIHC trans rs57549656 0.799 rs56348918 chr19:2710486 C/T cg08586426 chr11:33915315 LMO2 -0.28 -6.1 -0.31 2.93e-9 Schizophrenia; LIHC cis rs798554 0.679 rs2527677 chr7:2882621 A/G cg13628971 chr7:2884303 GNA12 0.59 9.9 0.47 1.71e-20 Height; LIHC cis rs17685 0.753 rs869806 chr7:75688623 C/T cg04592579 chr7:75616294 TMEM120A 0.41 7.1 0.36 7.46e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs5769765 0.773 rs9616751 chr22:50222236 T/G cg02269571 chr22:50332266 NA -0.84 -10.16 -0.48 2.32e-21 Schizophrenia; LIHC cis rs7927771 0.864 rs755554 chr11:47432034 G/C cg20135002 chr11:47629003 NA 0.55 9.19 0.45 3.91e-18 Subjective well-being; LIHC cis rs6964587 0.626 rs10280301 chr7:91524258 A/T cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.22e-24 Breast cancer; LIHC cis rs9583531 0.509 rs9521923 chr13:111405462 C/T cg24331049 chr13:111365604 ING1 -0.74 -9.6 -0.46 1.75e-19 Coronary artery disease; LIHC cis rs8062405 0.728 rs8056890 chr16:28897452 G/A cg07451762 chr16:28383216 NA 0.33 6.03 0.31 4.23e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg27297192 chr10:134578999 INPP5A 0.51 7.62 0.38 2.58e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs5769765 0.954 rs5770707 chr22:50244533 G/A cg02269571 chr22:50332266 NA 0.59 8.37 0.41 1.46e-15 Schizophrenia; LIHC cis rs1494950 1.000 rs12512141 chr4:15013361 A/C cg12377275 chr4:15005593 CPEB2 -0.84 -7.53 -0.38 4.59e-13 Political ideology; LIHC cis rs11628318 0.515 rs4906248 chr14:103126570 A/T cg12046867 chr14:103022105 NA 0.39 5.92 0.3 7.82e-9 Platelet count; LIHC cis rs7296418 0.961 rs61955196 chr12:123451018 G/C cg00376283 chr12:123451042 ABCB9 0.75 12.87 0.57 3.51e-31 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17829318 chr4:37688612 RELL1 0.4 6.5 0.33 2.78e-10 Cognitive function; LIHC cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs7191439 0.858 rs11076701 chr16:88774525 A/G cg27087555 chr16:88793112 FAM38A -1.34 -9.95 -0.47 1.19e-20 Plateletcrit; LIHC cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg27572855 chr1:25598939 RHD 0.38 8.15 0.4 6.96e-15 Erythrocyte sedimentation rate; LIHC cis rs7903847 0.673 rs3818908 chr10:99132701 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11858249 chr21:45079790 HSF2BP;RRP1B 0.39 6.13 0.31 2.46e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs34638686 1 rs34638686 chr3:48682658 C/T cg07636037 chr3:49044803 WDR6 -0.55 -6.2 -0.32 1.67e-9 Educational attainment (years of education); LIHC cis rs1023500 0.573 rs133381 chr22:42470608 C/G cg00645731 chr22:42541494 CYP2D7P1 0.41 6.38 0.33 5.62e-10 Schizophrenia; LIHC cis rs9768139 0.683 rs4909178 chr7:158117752 T/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.97 -0.31 5.91e-9 Calcium levels; LIHC cis rs9640161 0.742 rs2108853 chr7:150017589 A/C cg10018233 chr7:150070692 REPIN1 0.54 9.06 0.44 1.02e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs477895 0.652 rs72920332 chr11:63947071 G/T cg18225595 chr11:63971243 STIP1 0.69 8.46 0.42 8.07e-16 Mean platelet volume; LIHC cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.11 0.31 2.79e-9 Menopause (age at onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24592846 chr11:129873229 NCRNA00167;PRDM10 0.43 6.1 0.31 2.88e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.592 rs4481089 chr22:41980892 T/C cg06634786 chr22:41940651 POLR3H -0.56 -5.92 -0.3 7.82e-9 Vitiligo; LIHC cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg12311346 chr5:56204834 C5orf35 -0.58 -7.42 -0.37 9.28e-13 Initial pursuit acceleration; LIHC cis rs4595586 0.546 rs2056159 chr12:39270417 C/G cg26384229 chr12:38710491 ALG10B 0.51 6.68 0.34 9.84e-11 Morning vs. evening chronotype; LIHC cis rs548181 0.545 rs1054997 chr11:125618813 G/A cg03464685 chr11:125439445 EI24 -0.79 -8.41 -0.41 1.15e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1712517 0.744 rs11191641 chr10:105052940 C/T cg05636881 chr10:105038444 INA 0.46 7.01 0.35 1.31e-11 Migraine; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg07677032 chr17:61819896 STRADA 0.44 6.33 0.32 7.63e-10 Prudent dietary pattern; LIHC cis rs7474896 0.537 rs1208587 chr10:38207759 A/G cg25427524 chr10:38739819 LOC399744 0.47 6.23 0.32 1.37e-9 Obesity (extreme); LIHC trans rs7246657 1.000 rs1529957 chr19:37739801 A/G cg10208301 chr11:6592745 DNHD1 0.43 6.04 0.31 4.05e-9 Coronary artery calcification; LIHC cis rs67311347 0.955 rs9821036 chr3:40379007 A/G cg24209194 chr3:40518798 ZNF619 0.45 6.47 0.33 3.34e-10 Renal cell carcinoma; LIHC cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg26119090 chr2:26468346 HADHA;HADHB 1.14 16.33 0.66 1e-44 Gut microbiome composition (summer); LIHC cis rs1801251 1.000 rs4973055 chr2:233720283 G/T cg25237894 chr2:233734115 C2orf82 -0.58 -11.33 -0.52 1.76e-25 Coronary artery disease; LIHC cis rs34779708 0.931 rs17591135 chr10:35465190 T/A cg03585969 chr10:35415529 CREM 0.87 13.11 0.58 4.23e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1577917 1.000 rs10944161 chr6:86630376 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.68 0.34 9.43e-11 Bipolar disorder; LIHC cis rs10769966 0.515 rs2568069 chr11:8977707 G/A cg00186954 chr11:8933980 ST5;C11orf17 0.36 5.82 0.3 1.36e-8 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg06481639 chr22:41940642 POLR3H -0.72 -6.74 -0.34 6.5500000000000006e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs3790645 1.000 rs282177 chr1:26899125 C/T cg17456097 chr1:26900765 RPS6KA1 0.42 5.94 0.31 6.95e-9 Glucose homeostasis traits; LIHC cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg16049864 chr8:95962084 TP53INP1 -0.67 -12.98 -0.57 1.31e-31 Type 2 diabetes; LIHC cis rs250677 0.687 rs250679 chr5:148434952 A/T cg12140854 chr5:148520817 ABLIM3 0.42 5.72 0.3 2.35e-8 Breast cancer; LIHC cis rs910316 0.763 rs175047 chr14:75479039 C/G cg08847533 chr14:75593920 NEK9 -0.88 -18.22 -0.7 2.48e-52 Height; LIHC cis rs16828019 0.852 rs71648534 chr1:41613747 G/T cg03962019 chr1:41807865 NA 0.53 7.51 0.38 5.27e-13 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.641 rs960385 chr6:146371074 G/A cg05347473 chr6:146136440 FBXO30 0.45 6.92 0.35 2.28e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs35110281 0.720 rs162380 chr21:44925283 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO -0.47 -6.1 -0.31 2.9e-9 Mean corpuscular volume; LIHC cis rs35110281 0.626 rs162367 chr21:44934857 A/G cg21573476 chr21:45109991 RRP1B -0.41 -7.3 -0.37 2e-12 Mean corpuscular volume; LIHC cis rs12594515 1.000 rs8043291 chr15:45996247 T/A cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs6586163 0.872 rs7910660 chr10:90743197 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.53 -7.76 -0.39 9.9e-14 Chronic lymphocytic leukemia; LIHC cis rs7927771 0.507 rs1483988 chr11:47899030 C/T cg20307385 chr11:47447363 PSMC3 0.72 10.61 0.5 6.32e-23 Subjective well-being; LIHC cis rs7572733 0.534 rs700683 chr2:198712332 G/A cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC trans rs7674212 0.570 rs6813563 chr4:104099110 G/A cg16471864 chr4:38666270 KLF3;FLJ13197 -0.43 -6.1 -0.31 2.8e-9 Type 2 diabetes; LIHC cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg13047869 chr3:10149882 C3orf24 0.55 6.49 0.33 3.01e-10 Alzheimer's disease; LIHC cis rs7000551 0.751 rs896379 chr8:22374200 C/T cg12081754 chr8:22256438 SLC39A14 0.44 7.3 0.37 2.03e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg00166722 chr3:10149974 C3orf24 0.53 6.2 0.32 1.67e-9 Alzheimer's disease; LIHC cis rs2637266 0.626 rs846616 chr10:78547311 A/G cg18941641 chr10:78392320 NA 0.28 6.09 0.31 3.04e-9 Pulmonary function; LIHC cis rs9814567 0.806 rs4535271 chr3:134321669 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.57 -9.37 -0.45 9.88e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1712517 0.773 rs1063461 chr10:105049105 C/G cg05636881 chr10:105038444 INA 0.45 6.9 0.35 2.53e-11 Migraine; LIHC cis rs9914988 0.943 rs9898892 chr17:27150750 T/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs8062405 0.755 rs1074631 chr16:28554108 A/G cg16576597 chr16:28551801 NUPR1 -0.47 -7.12 -0.36 6.56e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4700695 0.719 rs27046 chr5:65439964 G/C cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.53e-15 Facial morphology (factor 19); LIHC cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg03264133 chr6:25882463 NA -0.64 -9.14 -0.44 5.69e-18 Blood metabolite levels; LIHC cis rs28374715 0.662 rs72737786 chr15:41500361 G/T cg18705301 chr15:41695430 NDUFAF1 -0.88 -9.82 -0.47 3.29e-20 Ulcerative colitis; LIHC cis rs2439831 0.850 rs7169322 chr15:44131014 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.73 0.34 7.11e-11 Lung cancer in ever smokers; LIHC cis rs7520050 0.966 rs9429183 chr1:46524582 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.94 0.31 7.17e-9 Red blood cell count;Reticulocyte count; LIHC cis rs12927205 0.510 rs7185601 chr16:72035082 A/G cg14768367 chr16:72042858 DHODH 0.55 5.87 0.3 1.05e-8 Cholesterol, total;LDL cholesterol; LIHC cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg00166722 chr3:10149974 C3orf24 0.49 5.74 0.3 2.12e-8 Alzheimer's disease; LIHC cis rs34375054 0.660 rs900411 chr12:125612839 C/T cg25124228 chr12:125621409 AACS -0.4 -6.69 -0.34 9.35e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs7582180 0.663 rs4850930 chr2:100990955 T/C cg14675211 chr2:100938903 LONRF2 0.56 8.23 0.41 3.98e-15 Intelligence (multi-trait analysis); LIHC cis rs7914558 0.966 rs10786724 chr10:104668942 A/G cg15744005 chr10:104629667 AS3MT -0.4 -9.05 -0.44 1.08e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1005277 0.579 rs2474572 chr10:38385316 A/G cg00409905 chr10:38381863 ZNF37A -0.59 -10.31 -0.49 6.75e-22 Extrinsic epigenetic age acceleration; LIHC cis rs11628318 0.660 rs12887323 chr14:103083322 T/C cg01864069 chr14:103024347 NA -0.46 -7.35 -0.37 1.5e-12 Platelet count; LIHC cis rs425277 0.585 rs364677 chr1:2071765 A/G cg24578937 chr1:2090814 PRKCZ -0.34 -6.11 -0.31 2.72e-9 Height; LIHC cis rs6594499 0.872 rs10045255 chr5:110438357 C/T cg04022379 chr5:110408740 TSLP -0.49 -8.2 -0.41 4.98e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs17818399 0.620 rs6544906 chr2:46863872 A/C cg02822958 chr2:46747628 ATP6V1E2 0.36 5.84 0.3 1.24e-8 Height; LIHC cis rs11098499 0.657 rs7664458 chr4:120371967 A/G cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs904251 0.861 rs1757180 chr6:37486145 T/C cg01843034 chr6:37503916 NA -0.47 -7.28 -0.37 2.35e-12 Cognitive performance; LIHC cis rs17401966 0.931 rs2185252 chr1:10415912 T/C cg15208524 chr1:10270712 KIF1B 0.41 6.16 0.32 2.08e-9 Hepatocellular carcinoma; LIHC trans rs1814175 0.592 rs1794161 chr11:49898825 A/C cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg06874399 chr5:79704109 ZFYVE16 0.43 6.17 0.32 1.88e-9 Migraine with aura; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06712627 chr1:91966606 CDC7 -0.44 -6.13 -0.31 2.46e-9 Longevity; LIHC cis rs992157 0.764 rs62183964 chr2:219186592 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.22 0.48 1.37e-21 Colorectal cancer; LIHC cis rs34779708 0.931 rs72789609 chr10:35306206 C/T cg03585969 chr10:35415529 CREM 0.85 12.91 0.57 2.45e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2637266 0.846 rs2637260 chr10:78320346 C/T cg18941641 chr10:78392320 NA -0.28 -6.08 -0.31 3.15e-9 Pulmonary function; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05321960 chr1:155904084 KIAA0907 0.41 6.05 0.31 3.71e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3736485 0.934 rs2899475 chr15:51883051 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg11502198 chr6:26597334 ABT1 0.53 8.02 0.4 1.67e-14 Intelligence (multi-trait analysis); LIHC cis rs17685 0.712 rs10275521 chr7:75770972 T/C cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12579753 1.000 rs12580330 chr12:82241280 T/G cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs7739232 0.920 rs7748828 chr6:53517643 A/C cg06485521 chr6:53530600 KLHL31 -0.88 -5.87 -0.3 1.02e-8 Hip circumference adjusted for BMI; LIHC cis rs244293 0.831 rs8072090 chr17:53174434 A/T cg19360675 chr17:53046073 COX11;STXBP4 -0.47 -7.2 -0.36 3.94e-12 Menarche (age at onset); LIHC cis rs10883723 0.810 rs1056857 chr10:104240003 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.21 0.55 1.05e-28 Allergic disease (asthma, hay fever or eczema); LIHC cis rs539514 0.516 rs9318377 chr13:76410018 G/A cg04757411 chr13:76259545 LMO7 0.37 5.74 0.3 2.07e-8 Type 1 diabetes; LIHC cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg22442454 chr1:209979470 IRF6 -0.39 -5.92 -0.3 7.91e-9 Cleft lip with or without cleft palate; LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg00684032 chr4:1343700 KIAA1530 0.37 5.98 0.31 5.5e-9 Obesity-related traits; LIHC cis rs9309711 0.689 rs4535075 chr2:3481716 T/C cg10845886 chr2:3471009 TTC15 -0.44 -8.35 -0.41 1.67e-15 Neurofibrillary tangles; LIHC cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.13e-10 Alzheimer's disease; LIHC cis rs6545883 0.929 rs3821222 chr2:61713526 C/G cg14146966 chr2:61757674 XPO1 0.48 8.31 0.41 2.31e-15 Tuberculosis; LIHC cis rs1538970 0.962 rs9429077 chr1:45820667 C/A cg24296786 chr1:45957014 TESK2 -0.49 -7.33 -0.37 1.71e-12 Platelet count; LIHC cis rs79057730 0.528 rs4719313 chr7:822501 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.76 8.42 0.41 1.06e-15 Initial pursuit acceleration; LIHC cis rs1185460 0.565 rs584115 chr11:118938880 A/G cg23280166 chr11:118938394 VPS11 -0.45 -6.03 -0.31 4.37e-9 Coronary artery disease; LIHC cis rs10911251 0.528 rs10911266 chr1:183115097 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.61 0.5 6.15e-23 Colorectal cancer; LIHC cis rs7589728 0.844 rs77144652 chr2:88496684 G/A cg07952391 chr2:88470173 THNSL2 0.76 6.94 0.35 1.95e-11 Plasma clusterin levels; LIHC cis rs8058578 0.943 rs3747486 chr16:30786927 C/T cg02466173 chr16:30829666 NA -0.42 -6.72 -0.34 7.56e-11 Multiple myeloma; LIHC cis rs875971 0.929 rs12535036 chr7:65964063 G/T cg11764359 chr7:65958608 NA 0.91 16.89 0.67 5.59e-47 Aortic root size; LIHC cis rs10256972 0.706 rs12701969 chr7:1121849 A/G cg07308232 chr7:1071921 C7orf50 -0.48 -7.75 -0.39 1.03e-13 Longevity;Endometriosis; LIHC cis rs6429082 0.807 rs4659857 chr1:235581411 C/T cg26050004 chr1:235667680 B3GALNT2 -0.49 -7.47 -0.37 6.92e-13 Adiposity; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg13409248 chr3:40428643 ENTPD3 0.47 7.79 0.39 8.02e-14 Renal cell carcinoma; LIHC cis rs7727544 0.735 rs272879 chr5:131670546 C/G cg07395648 chr5:131743802 NA -0.3 -6.23 -0.32 1.34e-9 Blood metabolite levels; LIHC trans rs13098911 0.540 rs4388012 chr3:45996501 A/G cg21656520 chr2:210867290 RPE 0.85 6.08 0.31 3.19e-9 Celiac disease; LIHC cis rs3741404 0.825 rs11604782 chr11:63946650 G/A cg24431193 chr11:63883947 FLRT1;MACROD1 -0.41 -6.34 -0.32 7.24e-10 Platelet count; LIHC cis rs9811920 0.638 rs793461 chr3:99615758 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs986417 0.748 rs10136486 chr14:60946111 C/T cg27398547 chr14:60952738 C14orf39 0.81 9.4 0.45 8.33e-19 Gut microbiota (bacterial taxa); LIHC cis rs79976124 0.837 rs75346757 chr6:66648386 A/T cg07460842 chr6:66804631 NA 0.65 6.89 0.35 2.64e-11 Type 2 diabetes; LIHC trans rs56347314 0.587 rs17765644 chr17:69179492 C/T cg11497526 chr17:35902366 SYNRG 0.3 6.08 0.31 3.29e-9 Chin dimples; LIHC cis rs7617773 0.746 rs4371540 chr3:48353543 G/A cg11946769 chr3:48343235 NME6 0.91 11.33 0.52 1.81e-25 Coronary artery disease; LIHC cis rs2806561 0.729 rs35919647 chr1:23326072 C/T cg19743168 chr1:23544995 NA -0.38 -6.84 -0.35 3.72e-11 Height; LIHC cis rs6570726 0.791 rs6914203 chr6:145899975 C/A cg23711669 chr6:146136114 FBXO30 0.64 11.0 0.51 2.7e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs74417235 0.684 rs13179358 chr5:154059746 C/A cg08754654 chr5:154026448 NA 0.32 7.17 0.36 4.54e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs9309711 0.506 rs9284794 chr2:3492052 G/A cg15506890 chr2:3487001 NA -0.44 -6.85 -0.35 3.37e-11 Neurofibrillary tangles; LIHC cis rs1005277 0.522 rs289649 chr10:37975384 T/C cg25427524 chr10:38739819 LOC399744 -0.62 -11.8 -0.54 3.51e-27 Extrinsic epigenetic age acceleration; LIHC cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg11301795 chr4:187892539 NA -0.27 -7.07 -0.36 8.94e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg02290350 chr8:58132656 NA 0.47 8.61 0.42 2.81e-16 Developmental language disorder (linguistic errors); LIHC cis rs11190604 1.000 rs2489049 chr10:102350732 G/A cg07080220 chr10:102295463 HIF1AN 0.56 8.03 0.4 1.54e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs75064307 0.834 rs9288870 chr3:108113469 G/C cg03329597 chr3:108125523 MYH15 0.5 6.7 0.34 8.42e-11 Intelligence (multi-trait analysis); LIHC cis rs68170813 0.559 rs7800443 chr7:106910723 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.9 -0.3 8.7e-9 Coronary artery disease; LIHC cis rs9911578 1.000 rs9902994 chr17:56948722 T/A cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg02951883 chr7:2050386 MAD1L1 -0.67 -10.87 -0.51 7.62e-24 Bipolar disorder and schizophrenia; LIHC cis rs6598955 0.694 rs4659416 chr1:26580937 T/G cg04990556 chr1:26633338 UBXN11 -0.63 -10.44 -0.49 2.4e-22 Obesity-related traits; LIHC cis rs249954 0.512 rs703767 chr16:23661639 G/C cg05131483 chr16:23706242 ERN2 0.38 6.17 0.32 1.9e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs11608355 0.515 rs61941592 chr12:109930497 G/A cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs1018836 0.608 rs7843149 chr8:91474961 C/T cg16814680 chr8:91681699 NA -0.36 -5.81 -0.3 1.44e-8 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs208520 0.690 rs1776365 chr6:66834474 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -8.08 -0.4 1.12e-14 Exhaled nitric oxide output; LIHC cis rs7520050 0.833 rs1085242 chr1:46544224 T/A cg03146154 chr1:46216737 IPP -0.37 -6.08 -0.31 3.28e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7635838 0.684 rs2606750 chr3:11372151 T/C cg00170343 chr3:11313890 ATG7 0.59 10.02 0.48 6.76e-21 HDL cholesterol; LIHC cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 5.99 0.31 5.32e-9 Schizophrenia; LIHC cis rs477692 0.663 rs491929 chr10:131368111 G/A cg19680672 chr10:131412579 MGMT -0.39 -5.92 -0.31 7.71e-9 Response to temozolomide; LIHC cis rs6754311 0.597 rs2082729 chr2:136550109 C/T cg07305463 chr2:136567211 LCT 0.4 7.5 0.38 5.66e-13 Mosquito bite size; LIHC cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg04546413 chr19:29218101 NA 0.55 10.23 0.48 1.31e-21 Methadone dose in opioid dependence; LIHC cis rs9457247 0.602 rs13204839 chr6:167471119 G/A cg12798992 chr6:167411361 FGFR1OP 0.47 6.97 0.35 1.63e-11 Crohn's disease; LIHC cis rs240764 0.658 rs11155666 chr6:101234841 G/C cg09795085 chr6:101329169 ASCC3 -0.55 -7.64 -0.38 2.27e-13 Neuroticism; LIHC trans rs11098499 0.954 rs59866101 chr4:120296591 T/G cg25214090 chr10:38739885 LOC399744 0.55 8.66 0.42 1.95e-16 Corneal astigmatism; LIHC cis rs1823913 0.599 rs17412635 chr2:192159560 A/G cg12404831 chr2:192114017 MYO1B -0.28 -5.74 -0.3 2.11e-8 Obesity-related traits; LIHC cis rs12586317 0.547 rs2038254 chr14:35462134 C/T cg05294307 chr14:35346193 BAZ1A -0.5 -7.43 -0.37 8.87e-13 Psoriasis; LIHC cis rs6893300 0.560 rs1019443 chr5:179207547 A/G cg14593053 chr5:179126677 CANX -0.4 -7.12 -0.36 6.34e-12 Resting heart rate; LIHC trans rs1005277 0.563 rs2505215 chr10:38481273 A/G cg27523141 chr10:43048294 ZNF37B 0.38 6.34 0.32 7.24e-10 Extrinsic epigenetic age acceleration; LIHC cis rs929354 0.772 rs3802118 chr7:156986814 T/C cg05182265 chr7:156933206 UBE3C -0.32 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs317689 0.918 rs610192 chr12:69739941 T/C cg19645103 chr12:69753606 YEATS4 -0.44 -5.87 -0.3 1.02e-8 Response to diuretic therapy; LIHC cis rs6752107 0.936 rs1045100 chr2:234203597 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.52 7.82 0.39 6.55e-14 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4555082 0.834 rs2735816 chr14:105721603 C/G cg13114125 chr14:105738426 BRF1 0.68 9.29 0.45 1.81e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs2153535 0.541 rs6923558 chr6:8461467 T/G cg07606381 chr6:8435919 SLC35B3 0.79 11.57 0.53 2.46e-26 Motion sickness; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs6840360 0.571 rs718800 chr4:152549307 A/T cg22705602 chr4:152727874 NA 0.31 5.89 0.3 9.18e-9 Intelligence (multi-trait analysis); LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg05484376 chr2:27715224 FNDC4 0.37 6.35 0.32 6.78e-10 Total body bone mineral density; LIHC cis rs12477438 0.501 rs34272114 chr2:99737443 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs923375 1.000 rs923375 chr17:3393068 C/T cg26502414 chr17:2414945 METT10D -0.36 -5.74 -0.3 2.09e-8 Myopia (pathological); LIHC cis rs7584330 0.554 rs6706729 chr2:238398580 T/C cg08992911 chr2:238395768 MLPH 0.62 6.2 0.32 1.62e-9 Prostate cancer; LIHC cis rs8077889 0.871 rs17675370 chr17:41900030 T/C cg26893861 chr17:41843967 DUSP3 0.99 10.76 0.5 1.9e-23 Triglycerides; LIHC trans rs7613875 0.620 rs11721204 chr3:49982765 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.41 6.27 0.32 1.12e-9 Body mass index; LIHC cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.26 -0.61 1.62e-36 Alzheimer's disease; LIHC cis rs1707322 1.000 rs10789486 chr1:46408667 A/G cg06784218 chr1:46089804 CCDC17 0.34 6.22 0.32 1.47e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8067545 0.750 rs28637614 chr17:19985108 G/T cg13482628 chr17:19912719 NA 0.48 7.96 0.4 2.51e-14 Schizophrenia; LIHC cis rs7223966 1.000 rs11658740 chr17:61751069 A/G cg05941027 chr17:61774174 LIMD2 0.3 6.02 0.31 4.53e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs992157 0.700 rs10165153 chr2:219159629 T/C cg00012203 chr2:219082015 ARPC2 0.85 13.77 0.6 1.22e-34 Colorectal cancer; LIHC cis rs9640161 0.789 rs2373751 chr7:150021599 G/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.53 -8.82 -0.43 6.16e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs16958440 0.867 rs77149690 chr18:44697143 T/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.8 0.47 3.71e-20 Mean platelet volume; LIHC cis rs1005277 0.540 rs2224248 chr10:38451886 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 0.882 rs28366039 chr3:10028988 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.73 9.87 0.47 2.21e-20 Alzheimer's disease; LIHC trans rs916888 0.821 rs199514 chr17:44856881 G/A cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10489202 0.608 rs7553238 chr1:168076768 G/A cg24449463 chr1:168025552 DCAF6 -0.46 -6.41 -0.33 4.97e-10 Schizophrenia; LIHC cis rs12142240 0.660 rs72890715 chr1:46852077 A/G cg14993813 chr1:46806288 NSUN4 -0.66 -5.94 -0.31 6.85e-9 Menopause (age at onset); LIHC cis rs7249142 0.563 rs11669860 chr19:19277296 G/A cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.36 -5.81 -0.3 1.42e-8 IgG glycosylation; LIHC cis rs477895 1.000 rs2276014 chr11:64081445 G/A cg04317338 chr11:64019027 PLCB3 0.86 8.31 0.41 2.26e-15 Mean platelet volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02718464 chr13:41384019 SUGT1L1;SLC25A15;MIR621 -0.44 -6.36 -0.33 6.47e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1434579 0.865 rs12983504 chr19:44942959 G/A cg15540054 chr19:45004280 ZNF180 0.57 7.97 0.4 2.39e-14 Tuberculosis; LIHC cis rs2645694 0.533 rs2645680 chr4:77820956 T/C cg03477792 chr4:77819574 ANKRD56 0.6 8.66 0.42 1.87e-16 Emphysema distribution in smoking; LIHC cis rs9303401 0.580 rs34076823 chr17:57114497 C/G cg25039879 chr17:56429692 SUPT4H1 0.76 8.71 0.43 1.34e-16 Cognitive test performance; LIHC cis rs9399135 0.967 rs9389258 chr6:135361140 T/C cg24558204 chr6:135376177 HBS1L 0.45 7.36 0.37 1.41e-12 Red blood cell count; LIHC cis rs5769765 0.817 rs9616212 chr22:50317687 G/A cg26441486 chr22:50317300 CRELD2 0.38 6.54 0.33 2.31e-10 Schizophrenia; LIHC cis rs868036 0.718 rs8030456 chr15:68076856 C/T cg24579218 chr15:68104479 NA -0.34 -5.83 -0.3 1.27e-8 Restless legs syndrome; LIHC cis rs807029 0.544 rs55646950 chr10:102760996 C/T cg17130504 chr10:102756923 LZTS2 0.55 7.49 0.38 6.03e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs208520 0.661 rs6937856 chr6:66867468 A/G cg07460842 chr6:66804631 NA -0.78 -8.54 -0.42 4.49e-16 Exhaled nitric oxide output; LIHC cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.71 -0.34 8.26e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs208520 0.690 rs2126120 chr6:66742754 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.93 0.43 2.63e-17 Exhaled nitric oxide output; LIHC cis rs10504229 0.679 rs73681882 chr8:58030038 A/G cg02290350 chr8:58132656 NA 0.31 7.17 0.36 4.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs8177253 0.965 rs4854762 chr3:133499063 A/G cg12373951 chr3:133503437 NA -0.68 -12.41 -0.56 1.82e-29 Iron status biomarkers; LIHC cis rs17539620 0.624 rs62432746 chr6:154838986 A/G cg20019720 chr6:154832845 CNKSR3 0.4 5.85 0.3 1.15e-8 Lipoprotein (a) levels; LIHC cis rs9787249 0.957 rs2274949 chr1:40221067 G/A cg02773041 chr1:40204384 PPIE 0.41 5.84 0.3 1.22e-8 Blood protein levels; LIHC cis rs6088580 0.634 rs9789792 chr20:32957709 G/A cg08999081 chr20:33150536 PIGU -0.66 -12.95 -0.57 1.67e-31 Glomerular filtration rate (creatinine); LIHC cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -10.46 -0.49 2.1e-22 Platelet count; LIHC cis rs7937682 1.000 rs11213980 chr11:111562692 A/T cg09085632 chr11:111637200 PPP2R1B 1.0 12.33 0.55 3.76e-29 Primary sclerosing cholangitis; LIHC cis rs11122272 0.735 rs2739518 chr1:231537633 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.75e-22 Hemoglobin concentration; LIHC cis rs477895 1.000 rs2286614 chr11:64068310 C/T cg04317338 chr11:64019027 PLCB3 0.87 8.53 0.42 4.82e-16 Mean platelet volume; LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg26338869 chr17:61819248 STRADA 0.52 7.13 0.36 5.88e-12 Height; LIHC cis rs8013055 0.846 rs10147392 chr14:105978537 T/G cg19700328 chr14:106028568 NA -0.34 -7.32 -0.37 1.8e-12 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs875971 1.000 rs10215948 chr7:65747786 G/A cg12463550 chr7:65579703 CRCP -0.41 -5.72 -0.3 2.28e-8 Aortic root size; LIHC cis rs4642101 0.662 rs4034942 chr3:12836792 C/T cg24848339 chr3:12840334 CAND2 0.32 6.58 0.34 1.76e-10 QRS complex (12-leadsum); LIHC cis rs10751667 0.666 rs4072741 chr11:976565 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs9399135 0.967 rs59329760 chr6:135342437 G/A cg24558204 chr6:135376177 HBS1L 0.41 6.75 0.34 6.44e-11 Red blood cell count; LIHC cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg12756686 chr19:29218302 NA 0.44 6.79 0.34 4.98e-11 Methadone dose in opioid dependence; LIHC cis rs1538970 0.816 rs3790583 chr1:45956828 C/G cg24296786 chr1:45957014 TESK2 -0.51 -7.52 -0.38 4.86e-13 Platelet count; LIHC cis rs6502050 0.835 rs4789724 chr17:80150546 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.92 -0.31 7.68e-9 Life satisfaction; LIHC cis rs919433 0.783 rs787979 chr2:198242868 A/T cg10820045 chr2:198174542 NA 0.54 8.56 0.42 3.82e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17106184 1.000 rs72904730 chr1:51342035 G/C cg07174182 chr1:51127561 FAF1 -0.62 -6.5 -0.33 2.91e-10 Type 2 diabetes; LIHC cis rs763014 0.966 rs4984903 chr16:680695 A/G cg27189623 chr16:705930 WDR90 0.42 7.04 0.36 1.06e-11 Height; LIHC cis rs12549902 0.932 rs6981607 chr8:41508168 A/C cg17182837 chr8:41585554 ANK1 -0.23 -5.76 -0.3 1.92e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs1568889 1.000 rs1464897 chr11:28034844 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.07 0.36 8.51e-12 Bipolar disorder; LIHC cis rs2070488 0.896 rs11914389 chr3:38527215 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.17 0.66 4.23e-44 Electrocardiographic conduction measures; LIHC cis rs4319547 1.000 rs6489071 chr12:123025576 C/G cg05707623 chr12:122985044 ZCCHC8 -0.62 -8.16 -0.4 6.28e-15 Body mass index; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24510909 chr7:44122661 POLM -0.54 -6.12 -0.31 2.54e-9 Systolic blood pressure; LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg10553204 chr2:20871195 GDF7 -0.42 -7.77 -0.39 9.5e-14 Abdominal aortic aneurysm; LIHC cis rs1144333 1.000 rs5745343 chr1:76273805 A/G cg03433033 chr1:76189801 ACADM -0.52 -8.14 -0.4 7.56e-15 Attention function in attention deficit hyperactive disorder; LIHC cis rs10744422 1.000 rs4759381 chr12:123348480 G/A cg25930673 chr12:123319894 HIP1R -0.93 -11.69 -0.53 8.71e-27 Schizophrenia; LIHC cis rs651907 0.557 rs11712748 chr3:101383562 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.97 0.57 1.49e-31 Colorectal cancer; LIHC cis rs12479064 0.724 rs737094 chr2:100089078 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.58 -6.3 -0.32 9.39e-10 Chronic sinus infection; LIHC trans rs10213084 1.000 rs10213084 chr4:147499338 G/T cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs1577917 0.655 rs1059307 chr6:86387888 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.41 7.45 0.37 7.66e-13 Response to antipsychotic treatment; LIHC cis rs9818758 0.607 rs9311439 chr3:49310408 A/G cg07636037 chr3:49044803 WDR6 -0.82 -8.32 -0.41 2.09e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs11098499 0.863 rs11947234 chr4:120474859 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.47 0.46 4.64e-19 Corneal astigmatism; LIHC cis rs12824058 0.831 rs4759657 chr12:130815818 G/A cg24229701 chr12:130821962 PIWIL1 0.44 6.77 0.34 5.55e-11 Menopause (age at onset); LIHC cis rs2439831 0.867 rs933941 chr15:43632226 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.76 0.67 1.87e-46 Lung cancer in ever smokers; LIHC cis rs4253772 0.550 rs6008729 chr22:46727428 C/G cg24881330 chr22:46731750 TRMU -0.63 -6.58 -0.34 1.76e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs2576037 0.583 rs4890698 chr18:44489725 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.81 -0.3 1.45e-8 Personality dimensions; LIHC cis rs6584283 0.875 rs1548962 chr10:101289735 C/G cg06854084 chr10:101292507 NKX2-3 0.32 5.84 0.3 1.23e-8 Ulcerative colitis; LIHC cis rs1059312 1.000 rs7135987 chr12:129280117 G/A cg09035930 chr12:129282057 SLC15A4 0.69 13.29 0.58 8.71e-33 Systemic lupus erythematosus; LIHC cis rs3736485 0.966 rs7174435 chr15:51895065 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.25 -0.32 1.21e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1008375 0.931 rs7672369 chr4:17604825 A/G cg02297831 chr4:17616191 MED28 0.46 7.2 0.36 3.93e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10489202 0.632 rs202259 chr1:167962072 G/A cg24449463 chr1:168025552 DCAF6 -0.62 -9.71 -0.46 7.66e-20 Schizophrenia; LIHC cis rs6582630 0.502 rs12815350 chr12:38439921 A/T cg26384229 chr12:38710491 ALG10B 0.61 8.5 0.42 5.93e-16 Drug-induced liver injury (flucloxacillin); LIHC trans rs35110281 0.806 rs1454649 chr21:45032982 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.15 0.32 2.14e-9 Mean corpuscular volume; LIHC cis rs1023500 0.506 rs6002625 chr22:42517689 A/G cg05082376 chr22:42548792 NA 0.4 5.84 0.3 1.25e-8 Schizophrenia; LIHC cis rs9814567 0.712 rs4306900 chr3:134334327 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.58 9.36 0.45 1.07e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6570726 0.791 rs6570693 chr6:145910841 C/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.31 -0.32 8.87e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1075232 1.000 rs12438318 chr15:31680445 G/A cg01030201 chr15:31746330 NA -0.79 -6.11 -0.31 2.7e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs916888 0.687 rs199456 chr17:44797919 C/T cg01570182 chr17:44337453 NA 1.02 10.23 0.48 1.29e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7572733 0.534 rs10211202 chr2:198771941 A/G cg10820045 chr2:198174542 NA 0.47 7.18 0.36 4.28e-12 Dermatomyositis; LIHC cis rs6138458 1.000 rs7268095 chr20:24972333 C/T cg26195577 chr20:24973756 C20orf3 1.2 15.85 0.65 8.12e-43 Blood protein levels; LIHC cis rs769267 1.000 rs769267 chr19:19446936 A/G cg03709012 chr19:19516395 GATAD2A 0.92 15.94 0.65 3.78e-43 Tonsillectomy; LIHC trans rs2270927 1.000 rs4546360 chr5:75577563 T/C cg13563193 chr19:33072644 PDCD5 0.98 10.23 0.48 1.3e-21 Mean corpuscular volume; LIHC cis rs1018836 0.828 rs10086462 chr8:91558089 A/G cg16814680 chr8:91681699 NA -0.54 -8.48 -0.42 6.69e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs9470366 0.527 rs10807170 chr6:36629444 C/T cg08179530 chr6:36648295 CDKN1A -0.54 -8.32 -0.41 2.15e-15 QRS duration; LIHC cis rs7584330 0.554 rs7559057 chr2:238435306 A/T cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.41e-9 Prostate cancer; LIHC trans rs1005277 0.602 rs1831315 chr10:38473353 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.54 0.33 2.19e-10 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg02290350 chr8:58132656 NA 0.38 7.98 0.4 2.2e-14 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg05185784 chr16:90016020 DEF8 -0.46 -6.17 -0.32 1.91e-9 Skin colour saturation; LIHC cis rs1003719 0.788 rs2835599 chr21:38466937 G/T cg10648535 chr21:38446584 PIGP;TTC3 0.75 11.53 0.53 3.22e-26 Eye color traits; LIHC cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg11062466 chr8:58055876 NA 0.39 5.9 0.3 8.84e-9 Developmental language disorder (linguistic errors); LIHC cis rs2777491 0.915 rs7178634 chr15:41634587 A/G cg18705301 chr15:41695430 NDUFAF1 -0.59 -9.03 -0.44 1.25e-17 Ulcerative colitis; LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg02993280 chr1:107599747 PRMT6 0.69 11.3 0.52 2.19e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4819052 0.851 rs13052344 chr21:46676101 C/T cg22633049 chr21:46681294 NA -0.36 -6.13 -0.31 2.47e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs66573146 0.634 rs56097119 chr4:7018692 C/G cg15105060 chr4:7024189 TBC1D14 -0.75 -6.22 -0.32 1.45e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7131987 1.000 rs7131987 chr12:29406488 G/T cg21486233 chr12:29375141 FAR2 0.32 6.36 0.33 6.44e-10 QT interval; LIHC trans rs116095464 0.558 rs10080225 chr5:232175 A/G cg00938859 chr5:1591904 SDHAP3 0.59 7.19 0.36 4.19e-12 Breast cancer; LIHC cis rs736408 0.677 rs1042779 chr3:52821011 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 5.89 0.3 9.21e-9 Bipolar disorder; LIHC cis rs8078723 0.901 rs709591 chr17:38175561 T/A cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.12 -0.44 6.77e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs4478037 0.822 rs9825335 chr3:33123292 A/C cg27203090 chr3:33138513 GLB1;TMPPE -0.52 -6.51 -0.33 2.6e-10 Major depressive disorder; LIHC cis rs2115536 1.000 rs11072871 chr15:80197931 T/C cg11839771 chr15:80205821 ST20 -0.32 -6.69 -0.34 9.34e-11 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs7100689 0.622 rs1340383 chr10:82095968 T/G cg01528321 chr10:82214614 TSPAN14 0.77 10.38 0.49 3.89e-22 Post bronchodilator FEV1; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26297968 chr2:211035960 C2orf67 -0.42 -6.95 -0.35 1.85e-11 Cognitive function; LIHC cis rs8062405 1.000 rs4788101 chr16:28867804 C/T cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9640161 0.789 rs13223702 chr7:150058968 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -7.57 -0.38 3.55e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs804280 0.525 rs1004712 chr8:11622293 C/T cg09232555 chr8:11619866 NA 0.33 5.85 0.3 1.13e-8 Myopia (pathological); LIHC trans rs9929218 1.000 rs4783570 chr16:68806539 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs1614887 1 rs1614887 chr6:26393021 A/G cg09904177 chr6:26538194 HMGN4 0.35 6.24 0.32 1.31e-9 Intelligence (multi-trait analysis);Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26461676 chr17:19140887 EPN2 0.5 7.01 0.35 1.29e-11 Lung function (FEV1/FVC); LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg05484376 chr2:27715224 FNDC4 0.39 6.53 0.33 2.36e-10 Total body bone mineral density; LIHC cis rs950169 0.881 rs150965 chr15:85080527 T/G cg03959625 chr15:84868606 LOC388152 0.48 6.73 0.34 7.07e-11 Schizophrenia; LIHC cis rs35146811 0.844 rs4424195 chr7:99642745 A/G cg13334819 chr7:99746414 C7orf59 -0.53 -7.78 -0.39 8.79e-14 Coronary artery disease; LIHC cis rs12086130 0.892 rs113588455 chr1:51494003 G/A cg07174182 chr1:51127561 FAF1 -0.88 -9.84 -0.47 2.7e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs9378688 1.000 rs3823287 chr6:2244721 A/C cg12303981 chr6:2244766 GMDS -0.48 -6.32 -0.32 8.22e-10 Caudate nucleus volume; LIHC cis rs1816752 0.905 rs4770680 chr13:25015248 T/C cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC cis rs2991971 0.967 rs644915 chr1:46007002 T/C cg15605315 chr1:45957053 TESK2 0.45 6.14 0.32 2.3e-9 High light scatter reticulocyte count; LIHC trans rs17685 0.712 rs60721456 chr7:75743820 T/A cg19862616 chr7:65841803 NCRNA00174 0.77 14.32 0.61 9.33e-37 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs477692 1.000 rs567700 chr10:131423126 C/T cg05714579 chr10:131428358 MGMT 0.45 7.4 0.37 1.09e-12 Response to temozolomide; LIHC cis rs208520 0.690 rs207119 chr6:66786408 C/T cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC cis rs1555322 0.530 rs2425042 chr20:33865895 G/A cg03689076 chr20:33865952 NA 0.57 6.56 0.33 1.97e-10 Attention deficit hyperactivity disorder; LIHC cis rs67311347 1.000 rs11129876 chr3:40401636 C/T cg16822855 chr3:40428330 ENTPD3 -0.35 -6.54 -0.33 2.28e-10 Renal cell carcinoma; LIHC cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.73 -0.3 2.25e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17376456 0.932 rs3940842 chr5:93534858 C/A cg25358565 chr5:93447407 FAM172A 1.1 9.99 0.48 8.88e-21 Diabetic retinopathy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14173624 chr17:72199366 RPL38 0.42 6.19 0.32 1.69e-9 Cognitive function; LIHC cis rs74544699 1.000 rs629315 chr4:74776218 C/T cg02530824 chr4:74847766 PF4 0.58 6.24 0.32 1.31e-9 Growth-regulated protein alpha levels; LIHC cis rs8141529 0.748 rs2064261 chr22:29287730 C/T cg02153584 chr22:29168773 CCDC117 0.52 8.22 0.41 4.29e-15 Lymphocyte counts; LIHC cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg16606324 chr3:10149918 C3orf24 0.5 5.77 0.3 1.76e-8 Alzheimer's disease; LIHC cis rs9911578 1.000 rs2531732 chr17:56548420 T/A cg05425664 chr17:57184151 TRIM37 0.58 8.49 0.42 6.53e-16 Intelligence (multi-trait analysis); LIHC cis rs7107174 0.892 rs11601866 chr11:78011153 G/A cg02023728 chr11:77925099 USP35 0.5 9.44 0.45 5.76e-19 Testicular germ cell tumor; LIHC cis rs7528419 1.000 rs7528419 chr1:109817192 A/G cg06804625 chr1:109812012 CELSR2 0.41 5.83 0.3 1.26e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs6495122 0.699 rs1378942 chr15:75077367 A/C cg14664628 chr15:75095509 CSK 0.57 8.02 0.4 1.66e-14 Caffeine consumption;Diastolic blood pressure;Coffee consumption; LIHC cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.15 -0.32 2.22e-9 Calcium levels; LIHC cis rs7587476 0.822 rs6726763 chr2:215681580 T/G cg04004882 chr2:215674386 BARD1 0.56 7.83 0.39 6.39e-14 Neuroblastoma; LIHC cis rs7651039 0.641 rs2455916 chr3:15667383 C/T cg16303742 chr3:15540471 COLQ 0.55 9.72 0.47 6.93e-20 Coronary heart disease; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg01007350 chr1:165551424 LOC400794 0.47 6.25 0.32 1.19e-9 Hip circumference; LIHC cis rs2120019 0.938 rs2289582 chr15:75310394 T/C cg17294928 chr15:75287854 SCAMP5 -0.49 -7.28 -0.37 2.38e-12 Blood trace element (Zn levels); LIHC cis rs9858542 0.953 rs35115732 chr3:49475155 T/C cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs12765878 0.934 rs58543155 chr10:105643244 G/A cg11005552 chr10:105648138 OBFC1 0.39 6.15 0.32 2.2e-9 Coronary artery disease; LIHC cis rs11951515 0.508 rs10059993 chr5:43598352 A/G cg01983248 chr5:43482804 C5orf28 -0.35 -5.87 -0.3 1.04e-8 Metabolite levels (X-11787); LIHC cis rs8017423 0.935 rs11621820 chr14:90727154 C/T cg14092571 chr14:90743983 NA -0.4 -6.27 -0.32 1.12e-9 Mortality in heart failure; LIHC cis rs644148 0.693 rs2686772 chr19:44999729 T/C cg15540054 chr19:45004280 ZNF180 -0.76 -10.52 -0.49 1.34e-22 Personality dimensions; LIHC cis rs2439831 0.850 rs3759790 chr15:44121030 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.7 0.34 8.58e-11 Lung cancer in ever smokers; LIHC cis rs2278034 0.516 rs9829709 chr3:195616673 G/A cg22809023 chr3:195622598 TNK2 0.47 6.97 0.35 1.64e-11 Bronchopulmonary dysplasia; LIHC cis rs644799 0.965 rs565771 chr11:95644179 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.66 9.13 0.44 6.32e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1143633 0.566 rs2708932 chr2:113690675 C/A cg12858261 chr2:113808755 IL1F8 -0.33 -5.75 -0.3 2e-8 Allergic disease (asthma, hay fever or eczema); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12296079 chr11:61849674 NA -0.39 -6.14 -0.32 2.23e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2439831 0.717 rs2470132 chr15:43835481 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.69 11.02 0.51 2.24e-24 Lung cancer in ever smokers; LIHC cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.68 -0.38 1.67e-13 Intelligence (multi-trait analysis); LIHC cis rs7613875 0.620 rs2526747 chr3:50082914 C/G cg24110177 chr3:50126178 RBM5 -0.55 -8.83 -0.43 5.7e-17 Body mass index; LIHC cis rs10097731 0.908 rs77317991 chr8:82032468 C/T cg25230327 chr8:82042993 NA -0.56 -6.68 -0.34 9.73e-11 Serum total protein level; LIHC trans rs2832191 0.716 rs9983051 chr21:30371890 C/T cg14791747 chr16:20752902 THUMPD1 -0.46 -6.41 -0.33 4.95e-10 Dental caries; LIHC cis rs970821 0.667 rs6470183 chr8:124752408 C/T cg00283535 chr8:124749564 ANXA13 -0.44 -8.03 -0.4 1.61e-14 Breast cancer; LIHC cis rs992157 0.687 rs10206984 chr2:219066980 C/T cg00012203 chr2:219082015 ARPC2 0.92 16.47 0.67 2.85e-45 Colorectal cancer; LIHC cis rs80282103 0.618 rs11819230 chr10:1128812 A/G cg18964960 chr10:1102726 WDR37 0.66 5.9 0.3 8.54e-9 Glomerular filtration rate (creatinine); LIHC cis rs3806843 1.000 rs6898906 chr5:140169299 C/G cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs4900538 0.892 rs4906208 chr14:102956489 G/C cg18135206 chr14:102964638 TECPR2 0.95 16.39 0.66 5.75e-45 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs4780401 0.933 rs12926451 chr16:11819569 A/C cg01061890 chr16:11836724 TXNDC11 0.44 6.6 0.34 1.6e-10 Rheumatoid arthritis; LIHC cis rs7937682 0.564 rs11600652 chr11:111754368 A/T cg09085632 chr11:111637200 PPP2R1B 0.96 13.89 0.6 4.46e-35 Primary sclerosing cholangitis; LIHC cis rs79149102 0.579 rs12593476 chr15:75282092 A/C cg15902774 chr15:75289873 SCAMP5 0.4 5.83 0.3 1.29e-8 Lung cancer; LIHC cis rs67311347 1.000 rs7648952 chr3:40457038 C/T cg00656387 chr3:40428638 ENTPD3 -0.4 -6.65 -0.34 1.16e-10 Renal cell carcinoma; LIHC cis rs7412746 0.658 rs3768015 chr1:150812954 C/T cg18016565 chr1:150552671 MCL1 0.56 10.38 0.49 3.86e-22 Melanoma; LIHC cis rs4934494 0.681 rs12572928 chr10:91553549 C/T cg19698084 chr10:91461284 KIF20B -0.44 -5.72 -0.3 2.37e-8 Red blood cell count; LIHC cis rs8078723 0.690 rs56326707 chr17:38130139 C/T cg17467752 chr17:38218738 THRA 0.63 10.9 0.51 6.24e-24 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7312933 0.558 rs4768411 chr12:42855390 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.36 -0.41 1.61e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs3806843 0.735 rs801167 chr5:140081423 A/G cg16179182 chr5:140090404 VTRNA1-1 -0.37 -6.06 -0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs877282 0.853 rs10904544 chr10:756966 A/G cg22713356 chr15:30763199 NA 1.36 11.96 0.54 8.66e-28 Uric acid levels; LIHC trans rs2243480 1.000 rs316331 chr7:65604622 A/G cg10756647 chr7:56101905 PSPH -1.09 -13.39 -0.59 3.61e-33 Diabetic kidney disease; LIHC cis rs15676 0.947 rs2997913 chr9:131589033 C/T cg00228799 chr9:131580591 ENDOG 0.45 6.77 0.34 5.47e-11 Blood metabolite levels; LIHC cis rs16828019 0.929 rs2363805 chr1:41719434 G/T cg20697417 chr1:41786797 NA 0.34 6.55 0.33 2.11e-10 Intelligence (multi-trait analysis); LIHC cis rs61041384 1.000 rs4759367 chr12:123656544 G/A cg00376283 chr12:123451042 ABCB9 -0.57 -6.34 -0.32 7.45e-10 Schizophrenia; LIHC cis rs6088580 0.634 rs6142157 chr20:32984172 C/G cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs7208859 0.673 rs11652409 chr17:29182707 T/A cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3770081 0.590 rs12622715 chr2:86453563 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.72 -7.66 -0.38 1.98e-13 Facial emotion recognition (sad faces); LIHC cis rs7523273 0.606 rs761275 chr1:207972154 A/C cg22525895 chr1:207977042 MIR29B2 -0.62 -10.17 -0.48 2.09e-21 Schizophrenia; LIHC cis rs2404602 1.000 rs6495206 chr15:76870963 C/T cg23625390 chr15:77176239 SCAPER 0.38 6.36 0.33 6.31e-10 Blood metabolite levels; LIHC cis rs6942756 1.000 rs6949950 chr7:128914818 G/A cg02491457 chr7:128862824 NA -0.66 -10.4 -0.49 3.42e-22 White matter hyperintensity burden; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27333693 chr10:23002092 PIP4K2A 0.45 7.1 0.36 7.2e-12 Cognitive function; LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg21448741 chr8:58168803 NA 0.36 6.66 0.34 1.09e-10 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.553 rs7782024 chr7:1157502 G/T cg00990874 chr7:1149470 C7orf50 -0.71 -10.08 -0.48 4.42e-21 Bronchopulmonary dysplasia; LIHC cis rs992157 0.735 rs13388024 chr2:219097773 A/G cg00012203 chr2:219082015 ARPC2 0.92 16.75 0.67 2.14e-46 Colorectal cancer; LIHC cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg24549020 chr5:56110836 MAP3K1 0.55 7.03 0.36 1.16e-11 Initial pursuit acceleration; LIHC cis rs1801251 1.000 rs36007169 chr2:233621834 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.21 0.52 4.87e-25 Coronary artery disease; LIHC cis rs4906332 1.000 rs17617832 chr14:103943140 T/C cg04998671 chr14:104000505 TRMT61A -0.46 -6.21 -0.32 1.53e-9 Coronary artery disease; LIHC cis rs9814567 1.000 rs9989967 chr3:134238964 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2380220 0.810 rs66524640 chr6:95956566 T/C cg04719120 chr6:96025338 MANEA -0.59 -6.21 -0.32 1.52e-9 Behavioural disinhibition (generation interaction); LIHC cis rs1401999 1.000 rs6443926 chr3:183706630 A/C cg05044414 chr3:183734942 ABCC5 0.33 5.94 0.31 6.88e-9 Anterior chamber depth; LIHC cis rs798554 0.549 rs1623138 chr7:2899410 A/G cg13628971 chr7:2884303 GNA12 0.44 7.53 0.38 4.44e-13 Height; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.24 0.81 4.27e-80 Prudent dietary pattern; LIHC cis rs8013055 0.898 rs8014913 chr14:105977313 T/C cg19700328 chr14:106028568 NA -0.35 -7.52 -0.38 4.74e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs9911578 0.835 rs9904993 chr17:56468569 G/T cg12560992 chr17:57184187 TRIM37 -0.91 -15.18 -0.63 3.74e-40 Intelligence (multi-trait analysis); LIHC cis rs2239547 0.522 rs6773040 chr3:52935428 C/A cg18404041 chr3:52824283 ITIH1 0.42 5.83 0.3 1.28e-8 Schizophrenia; LIHC cis rs3749237 0.595 rs7637999 chr3:49535115 C/T cg03060546 chr3:49711283 APEH 0.63 10.23 0.48 1.35e-21 Resting heart rate; LIHC trans rs2727020 0.658 rs1851992 chr11:49438110 C/T cg18944383 chr4:111397179 ENPEP 0.25 6.22 0.32 1.44e-9 Coronary artery disease; LIHC cis rs9381040 0.610 rs6940462 chr6:41020223 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.07 -0.31 3.32e-9 Alzheimer's disease (late onset); LIHC trans rs875971 0.638 rs10278816 chr7:66036987 T/C cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg17243582 chr15:59969081 BNIP2 0.47 6.55 0.33 2.14e-10 Hepatitis; LIHC cis rs929354 0.772 rs1182441 chr7:157026650 A/G cg05182265 chr7:156933206 UBE3C 0.32 6.11 0.31 2.78e-9 Body mass index; LIHC cis rs2304069 0.507 rs4705407 chr5:149404983 G/T cg12661370 chr5:149340060 SLC26A2 0.64 10.24 0.48 1.2e-21 HIV-1 control; LIHC cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg21448741 chr8:58168803 NA 0.36 6.28 0.32 1.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.793 rs11543827 chr7:139032693 G/A cg07862535 chr7:139043722 LUC7L2 0.67 11.53 0.53 3.21e-26 Diisocyanate-induced asthma; LIHC cis rs7208859 0.623 rs9899268 chr17:29150255 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.12 0.4 8.57e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8177179 0.967 rs4443173 chr3:133439378 A/G cg24879335 chr3:133465180 TF 0.48 10.89 0.51 6.77e-24 Iron status biomarkers (transferrin levels); LIHC cis rs7937682 0.575 rs1346180 chr11:111715570 G/C cg09085632 chr11:111637200 PPP2R1B 0.96 14.39 0.61 5.01e-37 Primary sclerosing cholangitis; LIHC cis rs1555322 0.530 rs2250205 chr20:33867924 C/T cg03689076 chr20:33865952 NA 0.54 6.02 0.31 4.48e-9 Attention deficit hyperactivity disorder; LIHC cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg20887711 chr4:1340912 KIAA1530 0.49 7.2 0.36 3.95e-12 Longevity; LIHC cis rs6977660 0.714 rs10260866 chr7:19793151 T/C cg07541023 chr7:19748670 TWISTNB 0.5 7.48 0.38 6.17e-13 Thyroid stimulating hormone; LIHC cis rs10861342 1.000 rs1076 chr12:105562788 C/T cg23923672 chr12:105501055 KIAA1033 -0.65 -7.74 -0.39 1.12e-13 IgG glycosylation; LIHC cis rs17608059 0.566 rs17676459 chr17:13910515 A/G cg27005118 chr17:13972210 COX10 -0.35 -6.49 -0.33 3.02e-10 Temperament; LIHC cis rs7618501 0.633 rs6446189 chr3:50008566 A/G cg24110177 chr3:50126178 RBM5 -0.48 -7.68 -0.38 1.7e-13 Intelligence (multi-trait analysis); LIHC cis rs7712401 0.791 rs1870559 chr5:122116706 G/C cg18764291 chr5:122110994 SNX2 0.35 5.94 0.31 7.13e-9 Mean platelet volume; LIHC cis rs7208859 0.524 rs73263982 chr17:28920624 T/C cg14067834 chr17:29058358 SUZ12P 0.65 6.78 0.34 5.15e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9911578 1.000 rs10401050 chr17:56953786 A/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.579 rs1621040 chr10:38497232 T/C cg17219203 chr10:38645113 HSD17B7P2 -0.4 -5.79 -0.3 1.56e-8 Extrinsic epigenetic age acceleration; LIHC cis rs1023500 0.573 rs13057094 chr22:42470317 T/C cg00645731 chr22:42541494 CYP2D7P1 0.4 6.23 0.32 1.34e-9 Schizophrenia; LIHC cis rs875971 0.638 rs7793569 chr7:66116633 T/G cg00343986 chr7:65444356 GUSB -0.4 -5.87 -0.3 1.05e-8 Aortic root size; LIHC cis rs763121 0.889 rs9607557 chr22:39040279 G/A cg14440974 chr22:39074834 NA -0.35 -5.89 -0.3 9.27e-9 Menopause (age at onset); LIHC cis rs875971 0.862 rs9791712 chr7:66105163 C/G cg18252515 chr7:66147081 NA 0.48 7.0 0.35 1.36e-11 Aortic root size; LIHC cis rs96067 0.711 rs4653164 chr1:36627542 A/G cg24686825 chr1:36642396 MAP7D1 0.44 7.84 0.39 5.96e-14 Corneal structure; LIHC trans rs637571 0.512 rs660118 chr11:65735174 G/C cg17712092 chr4:129076599 LARP1B 0.75 13.27 0.58 1.08e-32 Eosinophil percentage of white cells; LIHC cis rs11190604 1.000 rs2495754 chr10:102324812 C/T cg07080220 chr10:102295463 HIF1AN 0.53 7.1 0.36 7.1e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7777484 0.517 rs2644306 chr7:2831602 A/G cg18446336 chr7:2847575 GNA12 -0.31 -6.02 -0.31 4.43e-9 Height; LIHC cis rs4144743 1.000 rs10438781 chr17:45323819 A/G cg18085866 chr17:45331354 ITGB3 -0.59 -8.53 -0.42 4.87e-16 Body mass index; LIHC cis rs4819052 0.851 rs7276591 chr21:46680156 C/T cg22633049 chr21:46681294 NA -0.35 -6.02 -0.31 4.48e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12744310 0.945 rs72665692 chr1:41775379 A/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs16958440 1.000 rs62096471 chr18:44643814 T/C cg17192377 chr18:44677553 HDHD2 0.6 6.76 0.34 5.88e-11 Sitting height ratio; LIHC cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg15691649 chr6:25882328 NA 0.48 6.78 0.34 5.34e-11 Blood metabolite levels; LIHC cis rs7772486 0.875 rs9390372 chr6:146363638 G/C cg23711669 chr6:146136114 FBXO30 0.6 10.67 0.5 3.87e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088580 0.567 rs6088520 chr20:33132364 A/G cg08999081 chr20:33150536 PIGU -0.65 -12.41 -0.56 1.81e-29 Glomerular filtration rate (creatinine); LIHC cis rs67460515 0.563 rs11922957 chr3:160828865 A/C cg03342759 chr3:160939853 NMD3 -0.62 -9.14 -0.44 5.77e-18 Parkinson's disease; LIHC cis rs2286885 0.965 rs4836548 chr9:129255456 G/A cg15282417 chr9:129245246 FAM125B 0.38 6.11 0.31 2.67e-9 Intraocular pressure; LIHC cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg13271783 chr10:134563150 INPP5A -0.6 -7.19 -0.36 4.14e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11190604 1.000 rs12219158 chr10:102302923 T/C cg07080220 chr10:102295463 HIF1AN 0.52 7.26 0.37 2.62e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg00484396 chr16:3507460 NAT15 0.44 8.35 0.41 1.74e-15 Tuberculosis; LIHC cis rs986417 1.000 rs1254286 chr14:60858300 T/C cg27398547 chr14:60952738 C14orf39 -0.74 -8.61 -0.42 2.74e-16 Gut microbiota (bacterial taxa); LIHC cis rs7726839 0.540 rs3762951 chr5:662613 C/G cg09021430 chr5:549028 NA -0.42 -8.52 -0.42 5.13e-16 Obesity-related traits; LIHC cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg18654377 chr3:49208889 KLHDC8B 0.48 5.74 0.3 2.09e-8 Menarche (age at onset); LIHC cis rs7903847 0.667 rs11189181 chr10:99144154 A/G cg06359132 chr10:99160096 RRP12 -0.43 -6.7 -0.34 8.71e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs12478296 0.581 rs56142391 chr2:242992248 C/T cg06360820 chr2:242988706 NA -0.83 -13.11 -0.58 4.27e-32 Obesity-related traits; LIHC cis rs9303401 0.614 rs28687626 chr17:57191904 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.17 0.55 1.43e-28 Cognitive test performance; LIHC cis rs2153535 0.580 rs1328862 chr6:8526681 A/T cg21535247 chr6:8435926 SLC35B3 0.65 8.6 0.42 2.93e-16 Motion sickness; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17146150 chr15:56657437 TEX9 0.42 6.17 0.32 1.92e-9 Cognitive function; LIHC trans rs634534 0.562 rs1151505 chr11:65734539 C/T cg17712092 chr4:129076599 LARP1B 0.7 11.6 0.53 1.81e-26 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs12701220 0.522 rs1881116 chr7:1053958 C/T cg04025307 chr7:1156635 C7orf50 0.45 6.48 0.33 3.22e-10 Bronchopulmonary dysplasia; LIHC cis rs1348850 0.872 rs12991272 chr2:178457339 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.09 0.51 1.32e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6918586 0.658 rs198830 chr6:26118246 T/A cg18357526 chr6:26021779 HIST1H4A -0.56 -8.19 -0.4 5.37e-15 Schizophrenia; LIHC cis rs6088580 0.524 rs6142210 chr20:33223012 C/T cg08999081 chr20:33150536 PIGU -0.43 -7.44 -0.37 8.4e-13 Glomerular filtration rate (creatinine); LIHC cis rs8084351 0.534 rs13381767 chr18:50574947 G/A cg24270629 chr18:50823537 DCC 0.4 5.99 0.31 5.31e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9649213 0.593 rs36017146 chr7:97974617 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.39 -6.15 -0.32 2.16e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26329349 chr8:67974458 COPS5 0.44 6.82 0.35 4.25e-11 Cognitive function; LIHC cis rs55882075 0.750 rs13184690 chr5:179146993 T/C cg14593053 chr5:179126677 CANX 0.45 8.18 0.4 5.6e-15 Monocyte percentage of white cells; LIHC cis rs9916302 0.904 rs11078897 chr17:37415870 C/T cg00129232 chr17:37814104 STARD3 -0.38 -6.11 -0.31 2.75e-9 Glomerular filtration rate (creatinine); LIHC cis rs12220238 0.915 rs11001020 chr10:76139217 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.59 5.82 0.3 1.38e-8 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02732134 chr10:101732382 DNMBP 0.4 6.23 0.32 1.41e-9 Pancreatic cancer; LIHC cis rs4908768 0.520 rs6695867 chr1:8730779 G/A cg20416874 chr1:8611966 RERE -0.62 -12.34 -0.56 3.41e-29 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1046896 0.514 rs9894705 chr17:80823758 A/C cg02711726 chr17:80685570 FN3KRP 0.46 8.48 0.42 6.9e-16 Glycated hemoglobin levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg10545927 chr1:33117362 RBBP4;ZBTB8OS -0.42 -6.59 -0.34 1.7e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg25204440 chr1:209979598 IRF6 0.54 8.14 0.4 7.41e-15 Cleft lip with or without cleft palate; LIHC cis rs651907 0.557 rs7612283 chr3:101434919 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.5 -0.33 2.85e-10 Colorectal cancer; LIHC cis rs2033711 0.870 rs7408188 chr19:58939389 T/G cg13877915 chr19:58951672 ZNF132 0.59 9.35 0.45 1.15e-18 Uric acid clearance; LIHC cis rs7246657 0.943 rs4801803 chr19:37966923 A/G cg23950597 chr19:37808831 NA 0.48 6.23 0.32 1.35e-9 Coronary artery calcification; LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg13395646 chr4:1353034 KIAA1530 -0.44 -6.25 -0.32 1.21e-9 Longevity; LIHC cis rs611744 0.870 rs640068 chr8:109158002 A/G cg18478394 chr8:109455254 TTC35 0.37 6.44 0.33 4.05e-10 Dupuytren's disease; LIHC cis rs700651 0.789 rs892514 chr2:198905270 T/C cg03934865 chr2:198174659 NA 0.47 6.56 0.33 1.95e-10 Intracranial aneurysm; LIHC cis rs9733 0.596 rs12085275 chr1:150650265 T/C cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Tonsillectomy; LIHC cis rs2073300 1.000 rs6132626 chr20:23444672 T/C cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7937890 0.559 rs2575823 chr11:14521354 C/A cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs709400 0.643 rs11621777 chr14:104072090 A/G cg26031613 chr14:104095156 KLC1 1.15 15.1 0.63 7.52e-40 Body mass index; LIHC cis rs8005677 1.000 rs1951119 chr14:23388326 A/C cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs7107174 1.000 rs2512535 chr11:77971468 C/T cg02023728 chr11:77925099 USP35 0.44 8.59 0.42 3.21e-16 Testicular germ cell tumor; LIHC cis rs35110281 0.805 rs3788062 chr21:44991159 C/T cg01579765 chr21:45077557 HSF2BP -0.34 -6.56 -0.33 2.04e-10 Mean corpuscular volume; LIHC cis rs35306767 0.903 rs61833260 chr10:975148 T/G cg20503657 chr10:835505 NA 1.07 11.21 0.52 4.87e-25 Eosinophil percentage of granulocytes; LIHC cis rs1371867 0.846 rs1788167 chr8:101319996 C/T cg06636551 chr8:101224915 SPAG1 -0.47 -8.81 -0.43 6.44e-17 Atrioventricular conduction; LIHC cis rs1494950 1.000 rs2643077 chr4:14990765 T/C cg12377275 chr4:15005593 CPEB2 -0.79 -6.62 -0.34 1.35e-10 Political ideology; LIHC cis rs35110281 0.837 rs2838342 chr21:45077865 G/A cg04455712 chr21:45112962 RRP1B 0.45 7.67 0.38 1.77e-13 Mean corpuscular volume; LIHC cis rs2115630 0.653 rs61394864 chr15:85170174 T/C cg11189052 chr15:85197271 WDR73 -0.49 -7.58 -0.38 3.25e-13 P wave terminal force; LIHC cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg25364880 chr3:44379878 C3orf23 0.59 8.13 0.4 8.16e-15 Depressive symptoms; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T ch.7.1415213R chr7:66262805 RABGEF1 0.4 6.63 0.34 1.35e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.05 0.4 1.35e-14 Platelet count; LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg20295408 chr7:1910781 MAD1L1 -0.43 -6.36 -0.33 6.33e-10 Bipolar disorder and schizophrenia; LIHC cis rs11122272 0.735 rs2250749 chr1:231485763 C/G cg06096015 chr1:231504339 EGLN1 0.51 9.51 0.46 3.42e-19 Hemoglobin concentration; LIHC cis rs9467773 0.967 rs6941022 chr6:26553531 T/C cg09904177 chr6:26538194 HMGN4 0.65 13.8 0.6 9.51e-35 Intelligence (multi-trait analysis); LIHC cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg06697600 chr4:7070879 GRPEL1 -0.64 -10.31 -0.49 7.02e-22 Monocyte percentage of white cells; LIHC cis rs2408955 0.522 rs2051851 chr12:48485940 G/C cg21466736 chr12:48725269 NA 0.63 9.14 0.44 5.64e-18 Glycated hemoglobin levels; LIHC cis rs11718455 0.960 rs13059547 chr3:44004492 G/A cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs4948102 0.595 rs7793921 chr7:56120881 G/A cg12555334 chr7:56120290 CCT6A;PSPH 0.36 6.18 0.32 1.82e-9 Plasma homocysteine levels (post-methionine load test); LIHC cis rs1003719 0.762 rs3787780 chr21:38462614 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.76 11.7 0.53 7.91e-27 Eye color traits; LIHC cis rs12286929 0.639 rs10891802 chr11:115043888 C/A cg04055981 chr11:115044050 NA 0.39 6.5 0.33 2.82e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg16587974 chr5:76383162 LOC728723;ZBED3 -0.48 -6.3 -0.32 9.41e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6701037 0.566 rs13373754 chr1:175139275 C/A cg00321850 chr1:175162397 KIAA0040 0.47 7.72 0.39 1.28e-13 Alcohol dependence; LIHC cis rs9303401 0.538 rs10515155 chr17:56481944 A/G cg25039879 chr17:56429692 SUPT4H1 0.79 9.17 0.44 4.59e-18 Cognitive test performance; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg05277466 chr16:88082055 BANP 0.44 6.46 0.33 3.7e-10 Immature fraction of reticulocytes; LIHC cis rs35110281 0.782 rs2051407 chr21:45079245 T/C cg21573476 chr21:45109991 RRP1B -0.57 -10.79 -0.5 1.5e-23 Mean corpuscular volume; LIHC cis rs4555082 0.915 rs66527719 chr14:105750523 C/G cg13114125 chr14:105738426 BRF1 -0.72 -9.53 -0.46 2.93e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs7551222 0.716 rs4245738 chr1:204506107 C/T cg20240347 chr1:204465584 NA -0.36 -7.68 -0.38 1.64e-13 Schizophrenia; LIHC cis rs13343954 0.825 rs7259371 chr19:33534641 G/A cg27124370 chr19:33622961 WDR88 0.42 5.8 0.3 1.52e-8 Colorectal cancer; LIHC cis rs72627123 0.867 rs58894370 chr14:74485382 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.56 0.46 2.44e-19 Morning vs. evening chronotype; LIHC trans rs10506458 0.834 rs58821476 chr12:63389425 T/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.43 -0.49 2.72e-22 Hemostatic factors and hematological phenotypes; LIHC trans rs4566357 0.615 rs10174591 chr2:227913140 G/A cg16088116 chr21:44841560 SIK1 -0.4 -6.23 -0.32 1.4e-9 Coronary artery disease; LIHC cis rs9393692 0.645 rs28446029 chr6:26305801 C/G cg13736514 chr6:26305472 NA -0.4 -6.26 -0.32 1.14e-9 Educational attainment; LIHC cis rs7959452 0.590 rs7968629 chr12:69782857 G/A cg22834771 chr12:69754056 YEATS4 -0.52 -9.29 -0.45 1.79e-18 Blood protein levels; LIHC cis rs614226 1.000 rs1167725 chr12:120968559 A/T cg01236616 chr12:121019343 POP5 1.24 19.11 0.72 6.71e-56 Type 1 diabetes nephropathy; LIHC cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg18230493 chr5:56204884 C5orf35 0.45 6.07 0.31 3.47e-9 Initial pursuit acceleration; LIHC cis rs11098699 0.784 rs6838926 chr4:124219260 A/G cg09941581 chr4:124220074 SPATA5 0.32 6.29 0.32 9.63e-10 Mosquito bite size; LIHC cis rs2742417 0.603 rs2531755 chr3:45772742 T/C cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs6545883 0.929 rs2593626 chr2:61665184 C/A cg15711740 chr2:61764176 XPO1 -0.43 -6.06 -0.31 3.67e-9 Tuberculosis; LIHC cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg21734168 chr11:67353974 GSTP1 -0.26 -6.26 -0.32 1.12e-9 Mean corpuscular volume; LIHC cis rs2074585 0.806 rs8033813 chr15:90999715 A/T cg22089800 chr15:90895588 ZNF774 0.59 8.13 0.4 7.9e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs6089829 0.962 rs4997812 chr20:61663153 T/G cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs10865541 0.806 rs4971503 chr2:3417221 G/A cg11642891 chr2:3452563 TTC15 -0.45 -7.21 -0.36 3.52e-12 Obesity-related traits; LIHC cis rs2070488 0.965 rs1065800 chr3:38566480 C/T cg24069376 chr3:38537580 EXOG -0.39 -7.09 -0.36 7.92e-12 Electrocardiographic conduction measures; LIHC cis rs262150 1.000 rs262150 chr7:158777934 G/A cg19418458 chr7:158789849 NA -0.4 -6.76 -0.34 5.83e-11 Facial morphology (factor 20); LIHC cis rs2191566 0.845 rs7258517 chr19:44535999 G/T cg18700516 chr19:44507157 ZNF230 -0.37 -6.18 -0.32 1.83e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg07092213 chr7:1199455 ZFAND2A -0.47 -7.14 -0.36 5.49e-12 Longevity;Endometriosis; LIHC cis rs11792861 0.555 rs4978767 chr9:111762925 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.68 11.02 0.51 2.34e-24 Menarche (age at onset); LIHC cis rs1580019 0.587 rs7805311 chr7:32558302 A/G cg06627557 chr7:32535165 LSM5;AVL9 -1.12 -26.32 -0.82 3.17e-84 Cognitive ability; LIHC cis rs921968 0.608 rs11678428 chr2:219352598 C/T cg17980119 chr2:219472607 PLCD4 0.36 6.25 0.32 1.19e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7178375 1.000 rs4779797 chr15:31208425 C/T cg19680485 chr15:31195859 MTMR15 0.55 6.39 0.33 5.35e-10 Hypertriglyceridemia; LIHC cis rs2070488 0.804 rs13059256 chr3:38504315 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.76 12.77 0.57 8.31e-31 Electrocardiographic conduction measures; LIHC cis rs611744 0.967 rs686630 chr8:109233239 G/C cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs1707322 0.686 rs2991979 chr1:46055858 A/G cg06784218 chr1:46089804 CCDC17 -0.4 -7.02 -0.35 1.19e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs72627123 0.656 rs75646425 chr14:74529433 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.88 8.7 0.43 1.38e-16 Morning vs. evening chronotype; LIHC cis rs67460515 0.563 rs11713441 chr3:160906855 T/C cg03342759 chr3:160939853 NMD3 -0.6 -8.84 -0.43 5.04e-17 Parkinson's disease; LIHC cis rs9303401 0.659 rs9303399 chr17:56672309 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.14 0.58 3.2e-32 Cognitive test performance; LIHC cis rs10791323 0.720 rs2851117 chr11:133705905 A/G cg15485101 chr11:133734466 NA -0.24 -5.73 -0.3 2.21e-8 Childhood ear infection; LIHC cis rs7927771 0.524 rs10838740 chr11:47679980 A/G cg20307385 chr11:47447363 PSMC3 0.76 11.53 0.53 3.26e-26 Subjective well-being; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19266034 chr7:108210536 THAP5;DNAJB9 0.54 7.08 0.36 8.31e-12 Lung function (FEV1/FVC); LIHC trans rs1728785 1.000 rs1749793 chr16:68569312 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.2 0.32 1.62e-9 Ulcerative colitis; LIHC cis rs2153535 0.580 rs1034272 chr6:8469335 G/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC trans rs2727020 0.521 rs7131163 chr11:49574774 C/T cg03929089 chr4:120376271 NA -0.7 -10.26 -0.49 1e-21 Coronary artery disease; LIHC cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs17826219 0.568 rs59858012 chr17:29078582 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.45 0.33 3.79e-10 Body mass index; LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg07725925 chr16:89976287 TCF25 -0.42 -5.83 -0.3 1.31e-8 Skin colour saturation; LIHC cis rs2549003 1.000 rs6894655 chr5:131818649 T/C cg02551604 chr5:131831745 NA -0.44 -6.54 -0.33 2.24e-10 Asthma (sex interaction); LIHC cis rs80282103 0.618 rs56004802 chr10:1159187 C/T cg08668510 chr10:1095578 IDI1 0.63 6.14 0.31 2.35e-9 Glomerular filtration rate (creatinine); LIHC cis rs477692 1.000 rs565974 chr10:131423274 C/T cg05714579 chr10:131428358 MGMT 0.45 7.4 0.37 1.09e-12 Response to temozolomide; LIHC trans rs11098499 0.505 rs75122014 chr4:120362426 G/C cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs6430585 0.640 rs58301703 chr2:136532225 G/A cg07169764 chr2:136633963 MCM6 1.14 15.97 0.65 2.7e-43 Corneal structure; LIHC cis rs11711311 1.000 rs9879760 chr3:113457948 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.05 -0.36 9.75e-12 IgG glycosylation; LIHC cis rs4423214 1.000 rs2276362 chr11:71174452 A/G cg05163923 chr11:71159392 DHCR7 0.87 13.2 0.58 1.92e-32 Vitamin D levels; LIHC cis rs1577917 0.958 rs2225754 chr6:86449698 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.19 -0.52 5.73e-25 Response to antipsychotic treatment; LIHC cis rs13394619 0.775 rs10200851 chr2:11722082 C/T cg07314298 chr2:11723111 GREB1 -0.49 -9.32 -0.45 1.45e-18 Endometriosis; LIHC cis rs11190604 1.000 rs2295773 chr10:102265815 A/G cg07080220 chr10:102295463 HIF1AN 0.57 8.15 0.4 6.94e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3106136 0.678 rs17021531 chr4:95280514 A/C cg11021082 chr4:95130006 SMARCAD1 0.34 5.87 0.3 1.04e-8 Capecitabine sensitivity; LIHC cis rs67460515 0.892 rs11710489 chr3:161093332 G/A cg03342759 chr3:160939853 NMD3 -0.57 -8.38 -0.41 1.35e-15 Parkinson's disease; LIHC trans rs1814175 0.791 rs7395713 chr11:49877887 A/G cg15704280 chr7:45808275 SEPT13 -1.01 -23.35 -0.78 8.99e-73 Height; LIHC cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.1 -0.44 7.62e-18 Bipolar disorder; LIHC cis rs12887734 0.524 rs12588797 chr14:104300020 C/T cg24130564 chr14:104152367 KLC1 0.44 7.2 0.36 3.75e-12 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.44 -6.28 -0.32 1.04e-9 Height; LIHC cis rs12079745 1.000 rs12081562 chr1:169176266 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.71 -6.58 -0.34 1.81e-10 QT interval; LIHC cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg26944245 chr16:421049 TMEM8A;MRPL28 0.43 8.12 0.4 8.48e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs4891159 0.548 rs12454625 chr18:74128751 A/G cg24786174 chr18:74118243 ZNF516 0.84 17.59 0.69 9.04e-50 Longevity; LIHC cis rs875971 0.545 rs1638735 chr7:66095738 C/T cg11764359 chr7:65958608 NA 0.59 8.07 0.4 1.22e-14 Aortic root size; LIHC cis rs3824867 0.879 rs4752837 chr11:47465955 G/A cg20307385 chr11:47447363 PSMC3 0.58 7.78 0.39 8.74e-14 Mean corpuscular hemoglobin; LIHC cis rs9916302 0.904 rs1619021 chr17:37739274 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -12.85 -0.57 4.01e-31 Glomerular filtration rate (creatinine); LIHC cis rs60871478 0.730 rs62432226 chr7:792973 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.55 6.31 0.32 8.76e-10 Cerebrospinal P-tau181p levels; LIHC cis rs4919694 1.000 rs12266291 chr10:104806884 G/A cg04362960 chr10:104952993 NT5C2 1.14 8.87 0.43 4.02e-17 Arsenic metabolism; LIHC cis rs7249142 0.597 rs7250650 chr19:19285989 A/T cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -6.99 -0.35 1.48e-11 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16924120 chr12:118814149 SUDS3 0.46 6.51 0.33 2.68e-10 Pancreatic cancer; LIHC trans rs10411161 1.000 rs8109345 chr19:52364933 T/C cg22319618 chr22:45562946 NUP50 -0.52 -7.03 -0.36 1.1e-11 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13789711 chr9:139743225 PHPT1 0.37 6.19 0.32 1.72e-9 Cognitive function; LIHC cis rs9811920 0.609 rs793462 chr3:99616461 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.59 0.62 8.17e-38 Prudent dietary pattern; LIHC cis rs66573146 0.539 rs56659624 chr4:7069377 G/C cg02503808 chr4:7069936 GRPEL1 -0.81 -8.79 -0.43 7.37e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs35306767 0.714 rs12762955 chr10:1078782 A/C cg20503657 chr10:835505 NA 0.54 5.93 0.31 7.36e-9 Eosinophil percentage of granulocytes; LIHC cis rs6951245 0.882 rs10256720 chr7:1210825 C/G cg24642844 chr7:1081250 C7orf50 -0.8 -7.52 -0.38 4.89e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs919433 0.617 rs13018267 chr2:198545592 G/C cg03934865 chr2:198174659 NA -0.49 -7.2 -0.36 3.98e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7100689 0.646 rs1340376 chr10:82128963 A/G cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs67478160 0.643 rs3818085 chr14:104215985 C/T cg08213375 chr14:104286397 PPP1R13B 0.65 13.0 0.58 1.15e-31 Schizophrenia; LIHC cis rs66569888 0.789 rs66826026 chr2:106732879 C/T cg15412446 chr2:106886593 NA -0.69 -6.88 -0.35 2.79e-11 Facial morphology (factor 23); LIHC cis rs1008375 0.966 rs3796813 chr4:17591648 A/G cg16339924 chr4:17578868 LAP3 0.46 6.43 0.33 4.37e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9814567 1.000 rs4498009 chr3:134198008 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.73 -0.3 2.2e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3020736 0.519 rs5996116 chr22:42517492 G/A cg04733989 chr22:42467013 NAGA -0.64 -9.17 -0.44 4.47e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs7312933 1.000 rs11181328 chr12:42504679 T/G cg01256987 chr12:42539512 GXYLT1 -0.42 -7.01 -0.35 1.29e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9640161 0.789 rs1464753 chr7:150021350 G/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.79 -0.43 7.56e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg17178900 chr1:205818956 PM20D1 0.61 9.11 0.44 6.97e-18 Menarche (age at onset); LIHC cis rs7103648 0.735 rs3824869 chr11:47378245 T/C cg20307385 chr11:47447363 PSMC3 -0.87 -12.64 -0.56 2.5e-30 Diastolic blood pressure;Systolic blood pressure; LIHC trans rs116095464 0.558 rs2288457 chr5:231270 C/T cg00938859 chr5:1591904 SDHAP3 0.57 7.04 0.36 1.03e-11 Breast cancer; LIHC cis rs9916302 0.861 rs752314 chr17:37410700 C/T cg03013999 chr17:37608204 MED1 0.36 6.07 0.31 3.35e-9 Glomerular filtration rate (creatinine); LIHC trans rs526821 0.553 rs510095 chr11:55289154 T/C cg03929089 chr4:120376271 NA -0.46 -7.01 -0.35 1.28e-11 Pediatric bone mineral density (spine); LIHC cis rs2239547 0.522 rs2336669 chr3:52994138 C/T cg11645453 chr3:52864694 ITIH4 -0.23 -6.0 -0.31 5.15e-9 Schizophrenia; LIHC cis rs9733 0.596 rs7538493 chr1:150655421 T/C cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Tonsillectomy; LIHC cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg03452623 chr4:187889614 NA -0.32 -8.24 -0.41 3.65e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7945705 0.837 rs2742474 chr11:9002089 A/G cg12365402 chr11:9010492 NRIP3 -0.33 -8.46 -0.42 7.72e-16 Hemoglobin concentration; LIHC cis rs4319547 0.697 rs7974262 chr12:122896385 C/T cg05707623 chr12:122985044 ZCCHC8 0.56 7.35 0.37 1.47e-12 Body mass index; LIHC cis rs16854884 0.632 rs4563409 chr3:143682122 T/G cg06585982 chr3:143692056 C3orf58 0.59 7.78 0.39 8.9e-14 Economic and political preferences (feminism/equality); LIHC cis rs10876993 0.928 rs7136269 chr12:58075937 G/A cg15848620 chr12:58087721 OS9 -0.58 -8.02 -0.4 1.65e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs9611519 0.929 rs9611509 chr22:41565827 A/G cg03806693 chr22:41940476 POLR3H -0.7 -7.55 -0.38 3.91e-13 Neuroticism; LIHC cis rs12497850 0.864 rs4513485 chr3:49139966 G/A cg07636037 chr3:49044803 WDR6 0.87 15.07 0.63 9.92e-40 Parkinson's disease; LIHC cis rs10792665 0.573 rs7130900 chr11:82574135 C/T cg24227371 chr11:82718527 RAB30 -0.28 -6.49 -0.33 2.93e-10 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00648153 chr6:74364149 SLC17A5 0.45 6.22 0.32 1.48e-9 Pancreatic cancer; LIHC cis rs2976388 0.609 rs2585148 chr8:143796193 C/G cg13446199 chr8:143762866 PSCA -0.2 -5.79 -0.3 1.59e-8 Urinary tract infection frequency; LIHC cis rs732505 0.764 rs73920020 chr19:5583514 T/C cg26242866 chr19:5711310 LONP1 0.83 6.11 0.31 2.65e-9 vWF and FVIII levels; LIHC cis rs240764 0.658 rs9322212 chr6:101248474 T/C cg09795085 chr6:101329169 ASCC3 -0.41 -5.72 -0.3 2.38e-8 Neuroticism; LIHC cis rs7945705 0.967 rs10840147 chr11:8920704 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.06 0.36 9.39e-12 Hemoglobin concentration; LIHC cis rs10426930 0.714 rs858422 chr19:5049483 T/C cg18473234 chr19:5097819 KDM4B -0.55 -6.18 -0.32 1.86e-9 Monocyte percentage of white cells; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg21774865 chr7:157009442 UBE3C 0.42 6.81 0.35 4.49e-11 Immature fraction of reticulocytes; LIHC cis rs12286929 1.000 rs12286929 chr11:115022404 A/G cg04055981 chr11:115044050 NA 0.4 6.59 0.34 1.66e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9399135 0.967 rs2150681 chr6:135375232 A/G cg22676075 chr6:135203613 NA -0.42 -6.69 -0.34 9.1e-11 Red blood cell count; LIHC cis rs8017423 0.967 rs11626011 chr14:90693572 A/G cg04374321 chr14:90722782 PSMC1 0.74 14.2 0.61 2.61e-36 Mortality in heart failure; LIHC cis rs919433 0.679 rs13394214 chr2:198527371 C/T cg10820045 chr2:198174542 NA 0.47 7.44 0.37 7.99e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8103278 0.507 rs522769 chr19:46284520 G/A cg02376097 chr19:46275166 DMPK 0.54 9.36 0.45 1.07e-18 Coronary artery disease; LIHC cis rs903552 0.932 rs11858490 chr15:102007443 G/T cg00659931 chr15:102010125 PCSK6 0.47 6.49 0.33 2.95e-10 Diabetic kidney disease; LIHC cis rs11676348 0.751 rs6715591 chr2:219019871 T/C cg00012203 chr2:219082015 ARPC2 -0.51 -6.44 -0.33 3.95e-10 Ulcerative colitis; LIHC cis rs908922 0.676 rs526099 chr1:152497811 T/C cg23254163 chr1:152506842 NA 0.23 5.98 0.31 5.64e-9 Hair morphology; LIHC cis rs1215050 0.791 rs7434393 chr4:98768576 T/C cg05340658 chr4:99064831 C4orf37 0.4 5.95 0.31 6.72e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9790314 0.723 rs12631850 chr3:160883062 C/T cg03342759 chr3:160939853 NMD3 0.73 11.67 0.53 1.05e-26 Morning vs. evening chronotype; LIHC cis rs6089584 0.854 rs6061407 chr20:60622048 A/C cg23262073 chr20:60523788 NA -0.29 -6.23 -0.32 1.38e-9 Body mass index; LIHC cis rs28374715 0.578 rs17730888 chr15:41637547 A/G cg18705301 chr15:41695430 NDUFAF1 -1.2 -17.56 -0.69 1.16e-49 Ulcerative colitis; LIHC cis rs10791097 0.694 rs2236717 chr11:130739887 G/T cg14779329 chr11:130786720 SNX19 0.4 6.03 0.31 4.25e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2153535 0.542 rs4440510 chr6:8471818 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg00280220 chr17:61926910 NA 0.42 6.68 0.34 9.73e-11 Prudent dietary pattern; LIHC cis rs79149102 0.579 rs8034149 chr15:75311842 G/C cg16226627 chr15:75307476 SCAMP5 0.53 9.45 0.45 5.7e-19 Lung cancer; LIHC cis rs9309473 0.950 rs10206899 chr2:73900900 T/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.48 -0.33 3.23e-10 Metabolite levels; LIHC cis rs17152411 0.947 rs61873270 chr10:126595923 C/A cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs9910055 0.509 rs9916444 chr17:42313512 C/G cg19774624 chr17:42201019 HDAC5 -0.56 -7.79 -0.39 7.99e-14 Total body bone mineral density; LIHC cis rs644799 1.000 rs586498 chr11:95537828 C/T cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7582720 1.000 rs72934513 chr2:203927587 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1051424 0.651 rs1292063 chr17:57907768 T/A cg13753209 chr17:57696993 CLTC -0.73 -11.64 -0.53 1.35e-26 Obesity-related traits; LIHC cis rs5769707 0.839 rs73176988 chr22:49989649 G/T cg07959070 chr22:50026188 C22orf34 -0.3 -7.7 -0.38 1.44e-13 Monocyte count;Monocyte percentage of white cells; LIHC trans rs1814175 0.529 rs1988417 chr11:49932430 A/G cg18944383 chr4:111397179 ENPEP 0.38 8.94 0.44 2.41e-17 Height; LIHC cis rs8141529 0.956 rs132539 chr22:29304253 C/T cg02153584 chr22:29168773 CCDC117 0.41 6.21 0.32 1.54e-9 Lymphocyte counts; LIHC cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg23205692 chr1:25664452 TMEM50A 0.4 6.45 0.33 3.75e-10 Erythrocyte sedimentation rate; LIHC cis rs6456156 0.586 rs1407315 chr6:167468659 A/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.69 -0.43 1.56e-16 Primary biliary cholangitis; LIHC cis rs72627509 0.857 rs2227901 chr4:57798189 A/G cg26694713 chr4:57773883 REST -0.68 -9.49 -0.46 4.13e-19 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg02353165 chr6:42928485 GNMT 0.76 12.04 0.55 4.42e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs864537 0.618 rs1214595 chr1:167427557 G/A cg22356347 chr1:167427500 CD247 -0.43 -7.07 -0.36 8.9e-12 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs17376456 0.825 rs34967135 chr5:93221785 G/A cg25358565 chr5:93447407 FAM172A 1.05 9.76 0.47 5.19e-20 Diabetic retinopathy; LIHC cis rs8060686 0.623 rs58388686 chr16:68075439 A/G cg05110241 chr16:68378359 PRMT7 -0.53 -6.32 -0.32 8.34e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs2120019 1.000 rs12324912 chr15:75361006 G/A cg17294928 chr15:75287854 SCAMP5 -0.57 -8.73 -0.43 1.16e-16 Blood trace element (Zn levels); LIHC cis rs8180040 0.966 rs2101247 chr3:47494303 G/A cg16586182 chr3:47516702 SCAP 0.6 11.71 0.54 7.09e-27 Colorectal cancer; LIHC cis rs2404602 0.647 rs11633869 chr15:77133322 G/T cg03037974 chr15:76606532 NA 0.6 10.27 0.49 9.71e-22 Blood metabolite levels; LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg06873352 chr17:61820015 STRADA 0.68 11.66 0.53 1.15e-26 Prudent dietary pattern; LIHC cis rs9378688 0.654 rs2479011 chr6:2355749 C/T cg12303981 chr6:2244766 GMDS 0.41 5.82 0.3 1.35e-8 Caudate nucleus volume; LIHC cis rs9790314 0.690 rs7614375 chr3:160851331 A/T cg03342759 chr3:160939853 NMD3 -0.7 -9.76 -0.47 5.1e-20 Morning vs. evening chronotype; LIHC cis rs6598955 0.670 rs6676619 chr1:26539035 T/G cg00852783 chr1:26633632 UBXN11 0.47 7.97 0.4 2.37e-14 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25947998 chr8:42948467 SGK196 0.42 6.1 0.31 2.82e-9 Pancreatic cancer; LIHC cis rs13392177 0.672 rs1877715 chr2:219052546 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.59 8.21 0.41 4.56e-15 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs3806843 0.705 rs2530230 chr5:140088131 G/A cg19875535 chr5:140030758 IK -0.42 -6.89 -0.35 2.72e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs2836974 0.526 rs1888488 chr21:40686521 C/T cg17971929 chr21:40555470 PSMG1 -0.43 -6.58 -0.34 1.75e-10 Cognitive function; LIHC cis rs7534824 0.625 rs61782081 chr1:101507074 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.24 0.36 2.99e-12 Refractive astigmatism; LIHC cis rs7635838 0.596 rs443503 chr3:11261912 A/T cg00170343 chr3:11313890 ATG7 -0.51 -8.05 -0.4 1.38e-14 HDL cholesterol; LIHC cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg08067268 chr2:26466485 HADHB;HADHA -0.47 -6.73 -0.34 7.04e-11 Gut microbiome composition (summer); LIHC cis rs4742903 1.000 rs2274724 chr9:106860568 C/T cg14250997 chr9:106856677 SMC2 0.42 7.42 0.37 9.36e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2191566 0.960 rs11083732 chr19:44520743 T/C cg20607764 chr19:44506953 ZNF230 -0.41 -6.7 -0.34 8.79e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg00280220 chr17:61926910 NA -0.43 -6.83 -0.35 3.84e-11 Prudent dietary pattern; LIHC cis rs7829975 0.564 rs2921060 chr8:8317817 G/T cg06636001 chr8:8085503 FLJ10661 -0.66 -10.28 -0.49 8.65e-22 Mood instability; LIHC cis rs9309473 0.687 rs6546827 chr2:73606493 C/T cg20560298 chr2:73613845 ALMS1 -0.48 -7.85 -0.39 5.25e-14 Metabolite levels; LIHC cis rs10463316 0.894 rs7707964 chr5:150765475 C/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.54 -0.33 2.31e-10 Metabolite levels (Pyroglutamine); LIHC cis rs11792861 0.890 rs3750465 chr9:111900677 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.6 8.33 0.41 1.97e-15 Menarche (age at onset); LIHC cis rs7481584 0.581 rs406598 chr11:3076285 G/A cg25174290 chr11:3078921 CARS -0.4 -5.94 -0.31 7.11e-9 Calcium levels; LIHC cis rs9916302 0.706 rs8182252 chr17:37727950 T/C cg07936489 chr17:37558343 FBXL20 0.88 13.57 0.59 7.71e-34 Glomerular filtration rate (creatinine); LIHC cis rs16854884 0.657 rs6766685 chr3:143736916 C/T cg06585982 chr3:143692056 C3orf58 0.55 7.17 0.36 4.79e-12 Economic and political preferences (feminism/equality); LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.49e-13 Developmental language disorder (linguistic errors); LIHC cis rs7408868 0.831 rs7249115 chr19:15280765 A/G cg02272795 chr19:15279244 NOTCH3 -0.31 -6.24 -0.32 1.29e-9 Pulse pressure; LIHC cis rs6089584 0.888 rs6089624 chr20:60619907 C/G cg23262073 chr20:60523788 NA -0.28 -6.04 -0.31 4.03e-9 Body mass index; LIHC cis rs7772486 0.641 rs67882056 chr6:146416301 T/C cg23711669 chr6:146136114 FBXO30 0.54 8.03 0.4 1.61e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs6860806 0.661 rs6871350 chr5:131580220 A/G cg24060327 chr5:131705240 SLC22A5 -0.45 -5.72 -0.3 2.35e-8 Breast cancer; LIHC cis rs74233809 1.000 rs12413046 chr10:104871204 A/G cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.43e-9 Birth weight; LIHC cis rs1023500 0.596 rs133369 chr22:42463814 C/T cg04733989 chr22:42467013 NAGA 0.67 9.86 0.47 2.45e-20 Schizophrenia; LIHC cis rs2576037 0.526 rs626217 chr18:44429182 T/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.49 -7.18 -0.36 4.41e-12 Personality dimensions; LIHC cis rs10949834 0.730 rs2237503 chr7:73509326 G/C cg07137043 chr7:73588983 EIF4H -0.56 -6.19 -0.32 1.71e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs67311347 1.000 rs6762997 chr3:40478151 C/T cg00656387 chr3:40428638 ENTPD3 0.44 7.45 0.37 7.71e-13 Renal cell carcinoma; LIHC cis rs11676348 0.772 rs7422358 chr2:218952778 C/T cg00012203 chr2:219082015 ARPC2 -0.46 -6.07 -0.31 3.33e-9 Ulcerative colitis; LIHC cis rs6964587 1.000 rs2282975 chr7:91761638 A/G cg17063962 chr7:91808500 NA 1.01 19.44 0.72 3.13e-57 Breast cancer; LIHC cis rs11958404 0.615 rs6556333 chr5:157445659 T/C cg05962755 chr5:157440814 NA 0.63 8.24 0.41 3.77e-15 IgG glycosylation; LIHC cis rs919433 0.680 rs8539 chr2:198362018 A/G cg10820045 chr2:198174542 NA 0.45 7.21 0.36 3.68e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg02873525 chr19:48675305 NA 0.4 6.06 0.31 3.52e-9 Migraine with aura; LIHC cis rs1448094 0.512 rs56082822 chr12:86255475 C/T cg02569458 chr12:86230093 RASSF9 0.46 6.22 0.32 1.43e-9 Major depressive disorder; LIHC cis rs2073300 0.609 rs3746733 chr20:23349749 C/T cg16736954 chr20:23401023 NAPB 0.72 8.6 0.42 3.02e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2070488 0.965 rs13093640 chr3:38487176 A/G cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC cis rs4901869 0.966 rs4901870 chr14:59334221 A/T cg02291164 chr14:59296302 NA -0.48 -6.34 -0.32 7.41e-10 Panic disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07473001 chr8:73920952 TERF1 0.44 6.05 0.31 3.87e-9 Lung function (FEV1/FVC); LIHC trans rs1552244 0.515 rs67626468 chr3:10161518 C/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC cis rs9486719 0.741 rs2049927 chr6:96848958 C/G cg06623918 chr6:96969491 KIAA0776 -0.67 -6.5 -0.33 2.83e-10 Migraine;Coronary artery disease; LIHC cis rs7542091 0.704 rs12022221 chr1:210046178 A/C cg22029157 chr1:209979665 IRF6 0.34 5.88 0.3 1e-8 Monobrow; LIHC cis rs7129220 0.588 rs72860548 chr11:10128679 C/G cg01453529 chr11:10209919 SBF2 -0.39 -6.8 -0.35 4.7e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs16854884 0.660 rs990320 chr3:143796305 T/C cg06585982 chr3:143692056 C3orf58 0.42 5.85 0.3 1.13e-8 Economic and political preferences (feminism/equality); LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg27166718 chr6:118880109 PLN;C6orf204 0.53 6.16 0.32 2.08e-9 Diastolic blood pressure; LIHC cis rs11764590 0.724 rs1533829 chr7:2082841 A/G cg23043544 chr7:2124092 MAD1L1 -0.42 -6.87 -0.35 3.02e-11 Neuroticism; LIHC cis rs939574 1.000 rs1109866 chr2:220083279 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.96 -10.46 -0.49 2.05e-22 Platelet distribution width; LIHC cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg08888203 chr3:10149979 C3orf24 0.56 6.39 0.33 5.49e-10 Alzheimer's disease; LIHC cis rs61712019 0.785 rs66637022 chr2:77741882 C/T cg11252801 chr2:77748917 LRRTM4 0.53 8.36 0.41 1.61e-15 Schizophrenia; LIHC trans rs1814175 0.616 rs28417656 chr11:50040152 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs9916302 0.752 rs12150047 chr17:37601755 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -12.11 -0.55 2.54e-28 Glomerular filtration rate (creatinine); LIHC cis rs116095464 0.558 rs1968374 chr5:249025 A/C cg22496380 chr5:211416 CCDC127 -0.94 -8.83 -0.43 5.36e-17 Breast cancer; LIHC cis rs950169 0.881 rs72750843 chr15:85135783 C/T cg12863693 chr15:85201151 NMB 0.45 6.03 0.31 4.27e-9 Schizophrenia; LIHC trans rs916888 0.773 rs199457 chr17:44795469 C/T cg13957321 chr17:43675089 NA 0.5 7.97 0.4 2.46e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7772486 0.754 rs6570718 chr6:146088443 T/G cg13319975 chr6:146136371 FBXO30 0.42 6.72 0.34 7.62e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 8.87e-33 Prudent dietary pattern; LIHC trans rs2739330 0.828 rs2186366 chr22:24254113 A/G cg06437703 chr8:37914619 EIF4EBP1 0.52 7.68 0.38 1.7e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2257205 0.667 rs6503884 chr17:56940026 G/A cg05425664 chr17:57184151 TRIM37 -0.61 -6.69 -0.34 9.14e-11 Pancreatic cancer; LIHC cis rs1866706 0.963 rs7106148 chr11:12878142 C/T cg25843174 chr11:12811716 TEAD1 0.3 6.28 0.32 1.05e-9 Intelligence (multi-trait analysis); LIHC cis rs807029 0.533 rs3824783 chr10:102750851 C/T cg27255678 chr10:102756921 LZTS2 0.5 7.16 0.36 5.05e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4144743 0.528 rs2292866 chr17:45356782 T/C cg18085866 chr17:45331354 ITGB3 -0.6 -6.67 -0.34 1.03e-10 Body mass index; LIHC cis rs3112357 1.000 rs3110796 chr7:135377929 A/G cg20392616 chr7:135392013 SLC13A4 0.4 6.62 0.34 1.36e-10 Plantar warts; LIHC cis rs8005677 1.000 rs4981449 chr14:23388871 C/G cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs939574 0.790 rs114196239 chr2:220094307 G/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.87 6.36 0.33 6.41e-10 Platelet distribution width; LIHC cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.38e-12 Bipolar disorder; LIHC cis rs2303759 0.874 rs10411630 chr19:49891314 C/A cg24324837 chr19:49891574 CCDC155 0.39 6.04 0.31 3.95e-9 Multiple sclerosis; LIHC cis rs7772486 0.790 rs2249386 chr6:146186611 G/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.25 -0.32 1.24e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.859 rs62149714 chr2:61603869 T/G cg14146966 chr2:61757674 XPO1 -0.44 -7.3 -0.37 2.09e-12 Tuberculosis; LIHC cis rs10751667 0.714 rs7933889 chr11:972270 C/T cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs6545883 0.929 rs6705235 chr2:61713580 G/C cg14146966 chr2:61757674 XPO1 0.47 8.19 0.41 5.2e-15 Tuberculosis; LIHC cis rs4843747 0.671 rs28451517 chr16:88109127 A/C cg06050784 chr16:88016603 BANP 0.37 6.73 0.34 7.16e-11 Menopause (age at onset); LIHC cis rs6762477 0.748 rs2073726 chr3:50223593 T/A cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.58 -9.09 -0.44 8.35e-18 Menarche (age at onset); LIHC cis rs965469 0.779 rs6037541 chr20:3287704 G/C cg25506879 chr20:3388711 C20orf194 -0.5 -6.17 -0.32 1.92e-9 IFN-related cytopenia; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs910316 0.503 rs4903273 chr14:75441795 G/A cg08847533 chr14:75593920 NEK9 -0.84 -16.23 -0.66 2.5e-44 Height; LIHC cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg17971929 chr21:40555470 PSMG1 0.82 9.9 0.47 1.76e-20 Cognitive function; LIHC cis rs936229 0.705 rs936227 chr15:75131959 A/G cg14664628 chr15:75095509 CSK -0.56 -9.03 -0.44 1.3e-17 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs11792861 0.851 rs4542004 chr9:111814478 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.85 0.43 4.91e-17 Menarche (age at onset); LIHC cis rs1873147 0.569 rs11636033 chr15:63311091 G/T cg12160578 chr15:63334699 TPM1 -0.62 -8.3 -0.41 2.45e-15 Orofacial clefts; LIHC cis rs3799378 0.582 rs1796518 chr6:26388672 C/T cg09904177 chr6:26538194 HMGN4 -0.43 -6.64 -0.34 1.27e-10 Intelligence (multi-trait analysis); LIHC cis rs9660992 0.512 rs12123773 chr1:205122420 C/G cg21545522 chr1:205238299 TMCC2 0.3 5.74 0.3 2.08e-8 Mean corpuscular volume;Mean platelet volume; LIHC cis rs3731827 0.511 rs72843872 chr2:85820027 A/G cg16865965 chr2:85811662 VAMP5 0.42 5.85 0.3 1.14e-8 Prostate cancer; LIHC cis rs736408 0.500 rs2878762 chr3:52919002 T/C cg11645453 chr3:52864694 ITIH4 0.29 7.59 0.38 3.11e-13 Bipolar disorder; LIHC cis rs1577917 0.917 rs1838959 chr6:86556804 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.07 -0.4 1.22e-14 Response to antipsychotic treatment; LIHC cis rs703842 1.000 rs10877019 chr12:58172929 A/G cg18357645 chr12:58087776 OS9 0.44 6.74 0.34 6.57e-11 Multiple sclerosis; LIHC cis rs11190604 1.000 rs2495747 chr10:102328247 C/T cg07080220 chr10:102295463 HIF1AN 0.51 7.12 0.36 6.41e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg24209194 chr3:40518798 ZNF619 0.56 8.11 0.4 9.34e-15 Renal cell carcinoma; LIHC cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.64 5.71 0.3 2.43e-8 Platelet count; LIHC cis rs7306456 0.623 rs10902513 chr12:132693487 A/G cg07640336 chr12:132677496 NA 0.36 7.46 0.37 7.25e-13 Anti-saccade response; LIHC cis rs72781680 0.898 rs56303870 chr2:24086944 G/A cg08917208 chr2:24149416 ATAD2B 0.88 8.29 0.41 2.69e-15 Lymphocyte counts; LIHC cis rs3106136 0.814 rs6825005 chr4:95277009 T/C cg11021082 chr4:95130006 SMARCAD1 0.39 6.62 0.34 1.41e-10 Capecitabine sensitivity; LIHC cis rs2281845 0.533 rs112365857 chr1:201097222 G/C cg06714761 chr1:201096289 NA 0.35 5.87 0.3 1.04e-8 Permanent tooth development; LIHC trans rs1814175 0.817 rs11040700 chr11:50023832 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC cis rs13217239 0.646 rs4403259 chr6:26997617 C/T cg12292205 chr6:26970375 C6orf41 0.43 7.43 0.37 8.98e-13 Schizophrenia; LIHC cis rs10540 1.000 rs61876336 chr11:489537 C/T cg03352830 chr11:487213 PTDSS2 0.68 5.87 0.3 1.04e-8 Body mass index; LIHC cis rs2836974 0.627 rs8127986 chr21:40687211 A/T cg11890956 chr21:40555474 PSMG1 -0.48 -7.95 -0.4 2.69e-14 Cognitive function; LIHC cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg24250549 chr1:154909240 PMVK -0.66 -10.5 -0.49 1.52e-22 Prostate cancer; LIHC cis rs10883723 0.962 rs1056740 chr10:104236552 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 11.28 0.52 2.63e-25 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 4.04e-13 Bipolar disorder; LIHC trans rs637571 0.522 rs679581 chr11:65746653 A/G cg17712092 chr4:129076599 LARP1B 0.73 12.81 0.57 5.69e-31 Eosinophil percentage of white cells; LIHC trans rs1814175 0.616 rs10769644 chr11:49987676 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs7727544 0.735 rs272894 chr5:131662460 C/T cg07395648 chr5:131743802 NA -0.3 -6.26 -0.32 1.18e-9 Blood metabolite levels; LIHC cis rs8062405 0.755 rs4788076 chr16:28570005 C/T cg16576597 chr16:28551801 NUPR1 0.46 7.32 0.37 1.83e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1055129 0.560 rs2666003 chr17:73942976 G/A cg10935138 chr17:73851978 WBP2 0.49 7.22 0.36 3.33e-12 White matter hyperintensity burden; LIHC cis rs7659604 0.521 rs10001697 chr4:122677737 G/T cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.51e-11 Type 2 diabetes; LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg20295408 chr7:1910781 MAD1L1 -0.46 -6.82 -0.35 4.24e-11 Bipolar disorder and schizophrenia; LIHC cis rs9733 0.519 rs2184833 chr1:150675483 C/T cg15448220 chr1:150897856 SETDB1 0.43 6.76 0.34 5.86e-11 Tonsillectomy; LIHC cis rs1707322 0.929 rs785513 chr1:46538320 T/C cg06784218 chr1:46089804 CCDC17 -0.38 -6.95 -0.35 1.81e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7223966 1.000 rs16947042 chr17:61766457 T/G cg05941027 chr17:61774174 LIMD2 0.3 5.99 0.31 5.18e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs77637988 0.604 rs6722246 chr2:48597045 T/G cg00032884 chr2:48540671 FOXN2 0.38 5.94 0.31 6.95e-9 Joint mobility (Beighton score); LIHC cis rs6951245 0.872 rs11768895 chr7:1063691 T/C cg24642844 chr7:1081250 C7orf50 -0.72 -7.91 -0.39 3.69e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10484885 0.878 rs55750696 chr6:90552336 G/A cg13799429 chr6:90582589 CASP8AP2 -0.69 -6.36 -0.33 6.49e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg03874509 chr1:107600012 PRMT6 0.76 12.16 0.55 1.6e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12644436 0.628 rs721782 chr4:88781437 T/G cg06891869 chr4:88767617 MEPE 0.44 7.66 0.38 1.88e-13 HIV-1 viral setpoint; LIHC cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg05368731 chr17:41323189 NBR1 0.72 12.43 0.56 1.65e-29 Menopause (age at onset); LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg14709524 chr16:89940631 TCF25 0.59 7.53 0.38 4.51e-13 Skin colour saturation; LIHC cis rs34172651 0.517 rs11642954 chr16:24824248 G/A cg00339695 chr16:24857497 SLC5A11 0.74 10.69 0.5 3.27e-23 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.15 0.32 2.13e-9 Schizophrenia; LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg21724239 chr8:58056113 NA 0.58 7.63 0.38 2.4e-13 Developmental language disorder (linguistic errors); LIHC cis rs4725617 0.686 rs4283960 chr7:143103380 C/T cg03150622 chr7:143105826 EPHA1 0.7 9.73 0.47 6.73e-20 Blood protein levels; LIHC cis rs7551222 0.752 rs6681905 chr1:204535789 T/G cg20240347 chr1:204465584 NA -0.36 -7.61 -0.38 2.63e-13 Schizophrenia; LIHC cis rs765787 0.530 rs2413782 chr15:45538490 A/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs9611519 1.000 rs2057070 chr22:41564287 T/C cg03806693 chr22:41940476 POLR3H -0.7 -7.67 -0.38 1.82e-13 Neuroticism; LIHC cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg25072359 chr17:41440525 NA -0.4 -6.36 -0.33 6.47e-10 Menopause (age at onset); LIHC cis rs116095464 0.558 rs6881920 chr5:222411 T/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs2153535 0.580 rs9393016 chr6:8458573 T/A cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs6456156 0.524 rs6932740 chr6:167466439 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.68 -0.42 1.69e-16 Primary biliary cholangitis; LIHC cis rs769267 0.965 rs2315281 chr19:19480099 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 -0.39 -5.94 -0.31 6.83e-9 Tonsillectomy; LIHC cis rs9303401 0.527 rs2116450 chr17:56745561 C/T cg25039879 chr17:56429692 SUPT4H1 0.76 8.2 0.41 4.97e-15 Cognitive test performance; LIHC cis rs798554 0.610 rs2527696 chr7:2858315 T/C cg19717773 chr7:2847554 GNA12 -0.42 -7.45 -0.37 7.62e-13 Height; LIHC cis rs1023500 0.573 rs2269524 chr22:42475703 T/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.18 -0.32 1.78e-9 Schizophrenia; LIHC cis rs7107174 1.000 rs6592772 chr11:78015563 A/C cg02023728 chr11:77925099 USP35 0.5 9.5 0.46 3.65e-19 Testicular germ cell tumor; LIHC cis rs1023500 0.573 rs2413666 chr22:42459622 C/T cg00645731 chr22:42541494 CYP2D7P1 0.39 6.18 0.32 1.81e-9 Schizophrenia; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12928759 chr2:74756470 HTRA2;AUP1 -0.42 -6.47 -0.33 3.36e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs57920188 0.535 rs10915664 chr1:4093700 G/A cg20703997 chr1:4087676 NA 0.48 5.94 0.31 6.94e-9 Interleukin-17 levels; LIHC trans rs2243480 1.000 rs6974723 chr7:65637939 C/T cg10756647 chr7:56101905 PSPH -1.08 -13.26 -0.58 1.18e-32 Diabetic kidney disease; LIHC trans rs3783890 0.778 rs11622997 chr14:93819246 G/A cg02802420 chr16:69363236 PDF;COG8 0.32 6.05 0.31 3.72e-9 Body mass index; LIHC cis rs67460515 0.892 rs35100811 chr3:161084046 A/C cg03342759 chr3:160939853 NMD3 -0.57 -8.42 -0.41 1.04e-15 Parkinson's disease; LIHC trans rs60843830 0.964 rs17713568 chr2:242132 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.67 9.51 0.46 3.54e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg12463550 chr7:65579703 CRCP 0.67 6.96 0.35 1.7e-11 Diabetic kidney disease; LIHC cis rs2404602 0.716 rs12592171 chr15:76755133 G/C cg23625390 chr15:77176239 SCAPER 0.37 6.12 0.31 2.54e-9 Blood metabolite levels; LIHC cis rs9790314 0.521 rs1376122 chr3:161087857 A/G cg17135325 chr3:160939158 NMD3 0.42 6.09 0.31 3.07e-9 Morning vs. evening chronotype; LIHC cis rs2242116 0.727 rs6442040 chr3:46963035 C/A cg27129171 chr3:47204927 SETD2 0.48 7.61 0.38 2.76e-13 Birth weight; LIHC cis rs7944584 0.632 rs7116451 chr11:47322327 G/A cg20307385 chr11:47447363 PSMC3 0.58 6.42 0.33 4.6e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6088580 0.584 rs2378203 chr20:32993846 A/T cg08999081 chr20:33150536 PIGU -0.67 -13.26 -0.58 1.12e-32 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.874 rs6851169 chr4:120117510 T/C cg09307838 chr4:120376055 NA 0.52 7.67 0.38 1.76e-13 Corneal astigmatism; LIHC cis rs6426558 0.537 rs648877 chr1:227283614 A/G cg10327440 chr1:227177885 CDC42BPA 0.44 6.83 0.35 3.9e-11 Neutrophil percentage of white cells; LIHC cis rs743757 1.000 rs743757 chr3:50476378 C/G cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.52 -8.07 -0.4 1.2e-14 Diastolic blood pressure; LIHC cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg14393609 chr7:65229607 NA 0.41 6.84 0.35 3.69e-11 Calcium levels; LIHC cis rs9818758 0.607 rs66991555 chr3:49228643 A/G cg00383909 chr3:49044727 WDR6 0.81 6.8 0.35 4.74e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23651146 chr3:57261829 APPL1 -0.55 -6.12 -0.31 2.62e-9 Systolic blood pressure; LIHC cis rs1534166 0.602 rs3817524 chr3:133526403 C/T cg12373951 chr3:133503437 NA -0.48 -6.66 -0.34 1.13e-10 Alcohol consumption (transferrin glycosylation); LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg11494091 chr17:61959527 GH2 0.36 5.91 0.3 8.35e-9 Height; LIHC cis rs12701220 0.655 rs7778968 chr7:1144622 C/G cg00990874 chr7:1149470 C7orf50 -0.67 -9.54 -0.46 2.84e-19 Bronchopulmonary dysplasia; LIHC cis rs8017423 1.000 rs1959001 chr14:90667739 G/A cg04374321 chr14:90722782 PSMC1 0.71 13.4 0.59 3.35e-33 Mortality in heart failure; LIHC trans rs2000813 0.857 rs12326641 chr18:47102997 C/A cg01564661 chr14:105942636 CRIP2 0.34 6.25 0.32 1.2e-9 Coronary artery disease; LIHC cis rs12908161 1.000 rs34900908 chr15:85257599 G/A cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC cis rs9888615 1.000 rs7161281 chr14:53350479 A/G cg00686598 chr14:53173677 PSMC6 -0.5 -6.25 -0.32 1.22e-9 Systolic blood pressure; LIHC cis rs1400745 0.756 rs799682 chr14:35349984 G/C cg05294307 chr14:35346193 BAZ1A -0.46 -7.67 -0.38 1.83e-13 Monocyte count; LIHC trans rs116095464 0.558 rs10057674 chr5:266813 C/T cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs1577917 0.771 rs2758847 chr6:86349103 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -12.25 -0.55 7.35e-29 Response to antipsychotic treatment; LIHC cis rs10411936 0.712 rs9305079 chr19:16591464 C/T cg10248733 chr19:16607483 C19orf44;CALR3 0.52 6.98 0.35 1.51e-11 White blood cell count;Multiple sclerosis; LIHC cis rs4819052 0.851 rs7275870 chr21:46671214 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.77 0.39 9.12e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2257205 0.667 rs11651859 chr17:56731926 G/T cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs1451375 0.652 rs7803440 chr7:50625632 C/T cg14593290 chr7:50529359 DDC 0.49 7.86 0.39 5.03e-14 Malaria; LIHC cis rs9309711 0.922 rs13399524 chr2:3480206 C/G cg10845886 chr2:3471009 TTC15 -0.55 -10.3 -0.49 7.72e-22 Neurofibrillary tangles; LIHC cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg13047869 chr3:10149882 C3orf24 0.55 6.49 0.33 2.97e-10 Alzheimer's disease; LIHC cis rs7617773 0.780 rs7645425 chr3:48362369 A/T cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC trans rs4843747 0.671 rs72818577 chr16:88111181 G/A cg26811252 chr16:29126840 RRN3P2 0.43 7.04 0.36 1.09e-11 Menopause (age at onset); LIHC cis rs3862260 0.509 rs10802124 chr1:120164252 G/A cg11530693 chr1:120165357 ZNF697 0.48 7.59 0.38 3.02e-13 Systemic lupus erythematosus; LIHC cis rs7085104 0.632 rs6162 chr10:104596981 G/A cg15744005 chr10:104629667 AS3MT -0.41 -9.57 -0.46 2.27e-19 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg10755058 chr3:40428713 ENTPD3 -0.41 -7.23 -0.36 3.11e-12 Renal cell carcinoma; LIHC cis rs67311347 0.955 rs60554147 chr3:40472503 T/C cg09455208 chr3:40491958 NA 0.36 7.4 0.37 1.09e-12 Renal cell carcinoma; LIHC cis rs8062405 0.737 rs11861132 chr16:28871860 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs711245 0.572 rs3821150 chr2:36795233 G/A cg01206211 chr2:36825736 FEZ2 0.43 6.96 0.35 1.79e-11 Height; LIHC cis rs4820539 1.000 rs885965 chr22:23461425 A/G cg14186256 chr22:23484241 RTDR1 0.93 18.93 0.72 3.5e-55 Bone mineral density; LIHC cis rs2050392 0.624 rs303444 chr10:30729347 C/T cg18806716 chr10:30721971 MAP3K8 -0.41 -5.84 -0.3 1.22e-8 Inflammatory bowel disease; LIHC cis rs4423214 1.000 rs4423214 chr11:71173254 C/T cg24826892 chr11:71159390 DHCR7 0.47 6.12 0.31 2.55e-9 Vitamin D levels; LIHC cis rs10876993 0.715 rs2169987 chr12:58012111 G/A cg18357645 chr12:58087776 OS9 -0.49 -7.74 -0.39 1.1e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs2120019 1.000 rs12324912 chr15:75361006 G/A cg06012730 chr15:75315579 PPCDC -0.35 -6.32 -0.32 7.99e-10 Blood trace element (Zn levels); LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs2742417 0.603 rs1962800 chr3:45779943 C/T cg04837898 chr3:45731254 SACM1L -0.51 -8.67 -0.42 1.78e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs5769765 0.955 rs8135963 chr22:50301476 T/C cg26441486 chr22:50317300 CRELD2 0.35 6.17 0.32 1.88e-9 Schizophrenia; LIHC cis rs2991971 0.810 rs781058 chr1:45935056 C/G cg24296786 chr1:45957014 TESK2 -0.54 -8.4 -0.41 1.24e-15 High light scatter reticulocyte count; LIHC cis rs7909074 0.898 rs10793565 chr10:45388231 G/C cg05187965 chr10:45406764 TMEM72 -0.29 -7.36 -0.37 1.36e-12 Mean corpuscular volume; LIHC cis rs8141529 0.732 rs6005872 chr22:29172898 T/G cg15103426 chr22:29168792 CCDC117 0.67 11.68 0.53 9.47e-27 Lymphocyte counts; LIHC trans rs3960554 0.808 rs57721466 chr7:75710049 C/T cg19862616 chr7:65841803 NCRNA00174 0.61 8.37 0.41 1.54e-15 Eotaxin levels; LIHC cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg00484396 chr16:3507460 NAT15 0.44 8.41 0.41 1.14e-15 Tuberculosis; LIHC cis rs7677751 0.767 rs6846502 chr4:55062090 T/C cg17187183 chr4:55093834 PDGFRA 0.58 7.38 0.37 1.18e-12 Corneal astigmatism; LIHC trans rs62103177 0.714 rs28691615 chr18:77612254 C/T cg05926928 chr17:57297772 GDPD1 0.57 7.53 0.38 4.42e-13 Opioid sensitivity; LIHC cis rs9457247 1.000 rs408918 chr6:167399282 G/T cg12798992 chr6:167411361 FGFR1OP 0.61 10.15 0.48 2.53e-21 Crohn's disease; LIHC cis rs78456975 1.000 rs11899027 chr2:1560414 G/C cg01028140 chr2:1542097 TPO -0.54 -6.44 -0.33 4.01e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs548181 0.621 rs2912098 chr11:125528569 C/T cg03464685 chr11:125439445 EI24 0.87 9.63 0.46 1.37e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6545883 0.965 rs6734830 chr2:61731112 G/A cg14146966 chr2:61757674 XPO1 0.49 8.64 0.42 2.2e-16 Tuberculosis; LIHC cis rs9902453 0.838 rs7217638 chr17:28336772 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs1401999 1.000 rs939338 chr3:183704068 A/G cg01324343 chr3:183735012 ABCC5 -0.76 -12.93 -0.57 1.99e-31 Anterior chamber depth; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg00057700 chr10:124768526 ACADSB;IKZF5 -0.4 -6.1 -0.31 2.87e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs9420 0.961 rs11604333 chr11:57467035 C/G cg19752551 chr11:57585705 CTNND1 -0.53 -7.39 -0.37 1.16e-12 Schizophrenia; LIHC cis rs6500602 0.702 rs4786493 chr16:4500122 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.5 0.33 2.79e-10 Schizophrenia; LIHC cis rs6456156 0.586 rs6456149 chr6:167463902 T/C cg07741184 chr6:167504864 NA 0.29 7.06 0.36 9.48e-12 Primary biliary cholangitis; LIHC cis rs17685 0.753 rs2108274 chr7:75781636 C/A cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12142240 0.698 rs17361819 chr1:46828109 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.74 0.3 2.12e-8 Menopause (age at onset); LIHC cis rs6430585 0.591 rs61187091 chr2:136468238 G/A cg07169764 chr2:136633963 MCM6 0.71 8.81 0.43 6.18e-17 Corneal structure; LIHC cis rs600806 0.815 rs3768495 chr1:109935325 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs7607369 0.714 rs4674338 chr2:219647487 A/G cg02985541 chr2:219472218 PLCD4 0.36 5.77 0.3 1.77e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs4969178 0.965 rs11077362 chr17:76397219 A/T cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs4631830 0.896 rs7077830 chr10:51522276 C/G cg20129853 chr10:51489980 NA 0.4 8.78 0.43 7.92e-17 Prostate-specific antigen levels; LIHC cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg11890956 chr21:40555474 PSMG1 1.04 14.68 0.62 3.42e-38 Cognitive function; LIHC trans rs804280 0.662 rs11250164 chr8:11610686 C/T cg14651457 chr8:12611650 LONRF1 0.53 6.75 0.34 6.4e-11 Myopia (pathological); LIHC cis rs1008375 0.966 rs4698642 chr4:17679174 A/T cg02297831 chr4:17616191 MED28 0.41 6.64 0.34 1.25e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2933343 0.700 rs883602 chr3:128653952 A/G cg24203234 chr3:128598194 ACAD9 0.45 6.32 0.32 8.11e-10 IgG glycosylation; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg02951883 chr7:2050386 MAD1L1 -0.54 -8.01 -0.4 1.77e-14 Bipolar disorder and schizophrenia; LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg12016809 chr21:47604291 C21orf56 0.46 6.86 0.35 3.17e-11 Testicular germ cell tumor; LIHC cis rs3008870 1.000 rs2755244 chr1:67484470 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.93 -16.26 -0.66 1.86e-44 Lymphocyte percentage of white cells; LIHC cis rs7772486 0.686 rs1337839 chr6:146010239 A/G cg13319975 chr6:146136371 FBXO30 0.37 6.01 0.31 4.88e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10870270 1.000 rs4880263 chr10:133787629 C/T cg08754478 chr10:133766260 PPP2R2D -0.53 -7.77 -0.39 9.47e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC trans rs9747201 1.000 rs9747668 chr17:80161081 A/G cg07393940 chr7:158741817 NA 0.55 6.56 0.33 1.99e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7216064 0.954 rs8079291 chr17:65887622 A/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.35 -0.45 1.16e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs3809566 1.000 rs4774471 chr15:63332645 A/T cg05771511 chr15:63340396 TPM1 -0.46 -6.95 -0.35 1.88e-11 Platelet count; LIHC cis rs1669338 0.588 rs62228620 chr3:3184913 C/T cg16797762 chr3:3221439 CRBN -0.92 -8.18 -0.4 5.59e-15 White matter integrity; LIHC trans rs11098499 0.866 rs9991221 chr4:120292107 G/C cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs6582630 0.519 rs11182021 chr12:38443709 A/T cg26384229 chr12:38710491 ALG10B -0.58 -8.43 -0.41 9.86e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs933688 1.000 rs11950530 chr5:90688740 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.69 0.73 3.11e-58 Smoking behavior; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23628684 chr21:30446052 CCT8 0.44 6.94 0.35 2.03e-11 Cognitive function; LIHC cis rs7829975 0.658 rs907181 chr8:8702875 T/C cg06636001 chr8:8085503 FLJ10661 0.43 7.1 0.36 7.38e-12 Mood instability; LIHC cis rs1707322 1.000 rs11211237 chr1:46447329 G/C cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12594515 1.000 rs58368732 chr15:45990531 G/C cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.78e-19 Waist circumference;Weight; LIHC cis rs12477438 0.798 rs17708218 chr2:99696284 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.8 -11.96 -0.54 8.86e-28 Chronic sinus infection; LIHC cis rs7607369 0.714 rs55900247 chr2:219618708 T/C cg02176678 chr2:219576539 TTLL4 -0.44 -5.74 -0.3 2.06e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs6430585 0.878 rs9677760 chr2:136538939 T/A cg15123519 chr2:136567270 LCT 0.35 5.77 0.3 1.78e-8 Corneal structure; LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs17345786 0.798 rs1609159 chr3:101275902 A/C cg11279151 chr3:101281821 RG9MTD1 -0.54 -8.69 -0.43 1.51e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg23131131 chr22:24373011 LOC391322 -0.59 -7.95 -0.4 2.7e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6450176 1.000 rs4311394 chr5:53300662 A/G ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.66 -0.62 4.37e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6723226 0.803 rs176415 chr2:32649778 G/A cg02381751 chr2:32503542 YIPF4 -0.75 -11.55 -0.53 2.73e-26 Intelligence (multi-trait analysis); LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg21951975 chr1:209979733 IRF6 0.44 7.12 0.36 6.28e-12 Cleft lip with or without cleft palate; LIHC cis rs6089829 0.962 rs6062393 chr20:61663230 G/A cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.93 -0.31 7.36e-9 Total body bone mineral density; LIHC cis rs8180040 0.701 rs13066214 chr3:47033937 C/T cg02527881 chr3:46936655 PTH1R -0.32 -6.39 -0.33 5.49e-10 Colorectal cancer; LIHC cis rs2228479 0.850 rs11645240 chr16:89837326 T/C cg04013166 chr16:89971882 TCF25 0.51 6.45 0.33 3.9e-10 Skin colour saturation; LIHC cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.03 0.31 4.18e-9 Menopause (age at onset); LIHC cis rs11675119 0.501 rs9751941 chr2:3494262 C/T cg10845886 chr2:3471009 TTC15 -0.44 -7.81 -0.39 6.99e-14 Neurofibrillary tangles; LIHC cis rs7959452 0.590 rs6581889 chr12:69757429 T/C cg20891283 chr12:69753455 YEATS4 0.9 19.5 0.73 1.8e-57 Blood protein levels; LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg19635926 chr16:89946313 TCF25 0.56 7.51 0.38 5.34e-13 Skin colour saturation; LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg14004847 chr7:1930337 MAD1L1 -0.47 -6.9 -0.35 2.49e-11 Bipolar disorder and schizophrenia; LIHC cis rs471756 0.523 rs604470 chr9:223979 A/G cg14500300 chr9:211689 NA 0.28 6.26 0.32 1.12e-9 Mean platelet volume; LIHC cis rs8180040 1.000 rs1024037 chr3:47318449 C/A cg27129171 chr3:47204927 SETD2 -0.68 -11.48 -0.53 4.99e-26 Colorectal cancer; LIHC trans rs6952808 0.534 rs1113736 chr7:1992992 T/C cg04565464 chr8:145669602 NFKBIL2 0.38 6.28 0.32 1.01e-9 Bipolar disorder and schizophrenia; LIHC cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg13047869 chr3:10149882 C3orf24 -0.51 -6.22 -0.32 1.48e-9 Alzheimer's disease; LIHC trans rs2363709 1.000 rs6770280 chr3:67416712 T/C cg25028035 chr6:42016671 CCND3 -0.83 -6.16 -0.32 2.04e-9 IgE levels; LIHC cis rs250677 0.687 rs36044 chr5:148441128 T/C cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs903552 0.736 rs9806369 chr15:102008430 A/C cg16179521 chr15:102009894 PCSK6 -0.43 -5.75 -0.3 1.95e-8 Diabetic kidney disease; LIHC cis rs4243830 0.522 rs10864614 chr1:6596008 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.96 -12.24 -0.55 8.2e-29 Body mass index; LIHC cis rs8192917 1.000 rs10909625 chr14:25101629 A/G cg08766149 chr14:25103301 GZMB 0.34 7.76 0.39 9.94e-14 Vitiligo; LIHC cis rs11212260 0.655 rs79269916 chr11:107337478 G/A cg25435332 chr11:107328525 CWF19L2 0.84 8.24 0.41 3.8e-15 IgG glycosylation; LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs1728785 0.901 rs698711 chr16:68561955 C/T cg02972257 chr16:68554789 NA -0.52 -6.07 -0.31 3.33e-9 Ulcerative colitis; LIHC cis rs757081 0.667 rs644419 chr11:17212375 C/T cg15432903 chr11:17409602 KCNJ11 0.44 6.03 0.31 4.37e-9 Systolic blood pressure; LIHC cis rs2153535 0.601 rs2327059 chr6:8447071 A/G cg07606381 chr6:8435919 SLC35B3 0.78 11.53 0.53 3.21e-26 Motion sickness; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -6.83 -0.35 3.96e-11 Total body bone mineral density; LIHC cis rs7095944 0.584 rs10901814 chr10:126431281 G/C cg08799069 chr10:126477246 METTL10 -0.35 -6.05 -0.31 3.73e-9 Asthma; LIHC cis rs2153535 0.580 rs7341206 chr6:8470489 T/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs11098499 0.754 rs9999724 chr4:120239944 C/T cg09307838 chr4:120376055 NA 0.71 11.05 0.51 1.77e-24 Corneal astigmatism; LIHC cis rs9467773 1.000 rs9467782 chr6:26542773 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.9 0.6 4.02e-35 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.624 rs2320449 chr12:38224190 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg18000306 chr6:288505 NA 0.36 6.96 0.35 1.71e-11 Menopause (age at onset); LIHC cis rs17376456 0.877 rs10078194 chr5:93364310 A/C cg25358565 chr5:93447407 FAM172A 1.1 10.04 0.48 5.77e-21 Diabetic retinopathy; LIHC cis rs2204008 0.624 rs2320449 chr12:38224190 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs5753618 0.561 rs737684 chr22:31659827 C/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20859470 chr1:153963593 RPS27 0.43 6.38 0.33 5.68e-10 Cognitive function; LIHC trans rs7618501 0.635 rs34080578 chr3:50026029 A/C cg21659725 chr3:3221576 CRBN 0.71 11.58 0.53 2.16e-26 Intelligence (multi-trait analysis); LIHC cis rs244293 0.899 rs244344 chr17:53196998 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.5 -0.38 5.39e-13 Menarche (age at onset); LIHC cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg04546413 chr19:29218101 NA 0.56 10.36 0.49 4.79e-22 Methadone dose in opioid dependence; LIHC cis rs700651 0.685 rs976180 chr2:198880443 C/T cg00792783 chr2:198669748 PLCL1 -0.42 -6.09 -0.31 3.08e-9 Intracranial aneurysm; LIHC cis rs9309473 1.000 rs6756987 chr2:73687077 G/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.8 -0.34 4.77e-11 Metabolite levels; LIHC trans rs12753920 0.642 rs2893200 chr1:92608029 C/T cg15668468 chr10:118892869 VAX1 0.44 6.33 0.32 7.7e-10 Systemic lupus erythematosus; LIHC trans rs61931739 0.517 rs1844525 chr12:34103183 T/A cg26384229 chr12:38710491 ALG10B 0.53 7.29 0.37 2.14e-12 Morning vs. evening chronotype; LIHC cis rs6951245 0.744 rs10265758 chr7:1172518 C/T cg22907277 chr7:1156413 C7orf50 0.74 6.37 0.33 6.17e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg02993280 chr1:107599747 PRMT6 -0.68 -10.98 -0.51 3.09e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7666738 0.830 rs13140676 chr4:98804978 C/T cg05340658 chr4:99064831 C4orf37 0.63 11.49 0.53 4.5e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg22963979 chr7:1858916 MAD1L1 0.41 6.75 0.34 6.3e-11 Bipolar disorder and schizophrenia; LIHC cis rs3764618 1.000 rs2287754 chr19:49496494 C/T cg14640682 chr19:49496473 GYS1;RUVBL2 -0.72 -6.06 -0.31 3.55e-9 Follicule stimulating hormone; LIHC cis rs875971 0.617 rs810400 chr7:66022889 G/C cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC cis rs1355223 0.583 rs2941060 chr11:34879154 G/A cg24088639 chr11:34937564 PDHX;APIP -0.39 -5.99 -0.31 5.17e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1451375 1.000 rs2329342 chr7:50624971 A/G cg14593290 chr7:50529359 DDC -0.4 -6.6 -0.34 1.59e-10 Malaria; LIHC trans rs2243480 1.000 rs35046236 chr7:65408613 T/C cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs7116495 0.609 rs949323 chr11:71714528 T/G cg10381502 chr11:71823885 C11orf51 -1.03 -9.31 -0.45 1.59e-18 Severe influenza A (H1N1) infection; LIHC cis rs12893668 0.703 rs35026580 chr14:104042753 A/G cg24130564 chr14:104152367 KLC1 -0.54 -8.8 -0.43 6.79e-17 Reticulocyte count; LIHC cis rs769267 0.566 rs9304962 chr19:19679992 G/C cg03709012 chr19:19516395 GATAD2A -0.85 -12.38 -0.56 2.42e-29 Tonsillectomy; LIHC cis rs11588062 0.601 rs4660344 chr1:46805222 A/G cg06787764 chr1:46668870 C1orf190;POMGNT1 0.49 7.56 0.38 3.81e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs6598955 0.671 rs12090258 chr1:26644698 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.71 -7.22 -0.36 3.46e-12 Obesity-related traits; LIHC cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg13126279 chr21:47581558 C21orf56 -0.39 -5.96 -0.31 6.17e-9 Testicular germ cell tumor; LIHC trans rs947612 0.576 rs9359011 chr6:73706941 C/T cg13494037 chr12:24737079 C12orf67 0.39 6.42 0.33 4.58e-10 HIV-1 viral setpoint;Body mass index; LIHC cis rs595982 0.517 rs4801779 chr19:49406651 T/G cg21252483 chr19:49399788 TULP2 -0.57 -8.99 -0.44 1.69e-17 Red cell distribution width; LIHC cis rs829883 0.738 rs249854 chr12:98862772 G/A cg25150519 chr12:98850993 NA 0.69 10.86 0.51 8.06e-24 Colorectal adenoma (advanced); LIHC cis rs6088590 0.550 rs12624640 chr20:32952125 G/A cg24642439 chr20:33292090 TP53INP2 0.56 7.22 0.36 3.44e-12 Coronary artery disease; LIHC cis rs12986413 0.967 rs1074047 chr19:2158748 A/G cg09261902 chr19:2140048 AP3D1 0.38 6.38 0.33 5.62e-10 Height; LIHC cis rs709400 0.930 rs61996717 chr14:104048571 T/C cg26031613 chr14:104095156 KLC1 1.12 14.59 0.62 7.81e-38 Body mass index; LIHC cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg08888203 chr3:10149979 C3orf24 0.59 6.93 0.35 2.13e-11 Alzheimer's disease; LIHC cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg00166722 chr3:10149974 C3orf24 0.53 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC cis rs16854884 0.545 rs7650459 chr3:143658934 C/G cg06585982 chr3:143692056 C3orf58 0.5 7.09 0.36 7.64e-12 Economic and political preferences (feminism/equality); LIHC cis rs6504622 0.537 rs189899 chr17:45000529 G/C cg16759221 chr17:45003025 GOSR2 -0.32 -5.75 -0.3 2e-8 Orofacial clefts; LIHC cis rs7654585 0.782 rs2309288 chr4:25947097 C/A cg10409131 chr4:25915609 C4orf52 0.47 7.3 0.37 1.99e-12 Obesity-related traits; LIHC cis rs6754311 0.731 rs2322660 chr2:136557319 A/G cg15123519 chr2:136567270 LCT -0.45 -9.26 -0.45 2.36e-18 Mosquito bite size; LIHC cis rs709400 0.633 rs8019578 chr14:103977724 A/G cg26031613 chr14:104095156 KLC1 0.75 9.38 0.45 9.49e-19 Body mass index; LIHC trans rs75804782 0.641 rs56000747 chr2:239318541 T/G cg01134436 chr17:81009848 B3GNTL1 0.81 6.6 0.34 1.61e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs782590 0.967 rs17278044 chr2:55748217 G/C cg18811423 chr2:55921094 PNPT1 0.97 14.95 0.63 3.06e-39 Metabolic syndrome; LIHC cis rs6831352 0.918 rs2602896 chr4:100046207 C/T cg13256891 chr4:100009986 ADH5 -0.59 -6.05 -0.31 3.87e-9 Alcohol dependence; LIHC cis rs28735056 0.967 rs61090726 chr18:77631219 A/G cg20368463 chr18:77673604 PQLC1 -0.38 -6.72 -0.34 7.5e-11 Schizophrenia; LIHC cis rs3106136 0.843 rs11727030 chr4:95262665 A/G cg11021082 chr4:95130006 SMARCAD1 0.4 7.22 0.36 3.49e-12 Capecitabine sensitivity; LIHC cis rs6691722 0.503 rs1064842 chr1:24706269 A/G cg18323236 chr1:24743029 NIPAL3 0.39 7.24 0.36 2.95e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.81 -0.39 7.01e-14 Type 2 diabetes; LIHC cis rs858239 0.669 rs1990365 chr7:23115966 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.84 0.35 3.59e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs56235845 0.964 rs4075958 chr5:176784512 A/G cg06060754 chr5:176797920 RGS14 -0.72 -11.36 -0.52 1.36e-25 Hemoglobin concentration;Hematocrit; LIHC cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.633 rs4819289 chr21:45120237 A/G cg21573476 chr21:45109991 RRP1B -0.52 -10.24 -0.48 1.17e-21 Mean corpuscular volume; LIHC cis rs10911251 0.528 rs10911263 chr1:183115018 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.61 0.5 6.15e-23 Colorectal cancer; LIHC trans rs561341 0.941 rs501773 chr17:30314435 T/G cg20587970 chr11:113659929 NA -1.22 -10.55 -0.5 1.07e-22 Hip circumference adjusted for BMI; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC trans rs11722228 0.521 rs12501336 chr4:10137351 G/A cg26043149 chr18:55253948 FECH 0.99 14.44 0.62 3.15e-37 Gout;Urate levels;Serum uric acid levels; LIHC trans rs2749592 0.531 rs994804 chr10:37900140 A/C cg23533926 chr12:111358616 MYL2 0.31 6.05 0.31 3.88e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs875971 0.830 rs809025 chr7:65849819 C/G cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs8027181 1.000 rs7164727 chr15:73093991 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.47 7.17 0.36 4.57e-12 Triglyceride levels; LIHC cis rs826838 0.967 rs826879 chr12:39088999 A/C cg13010199 chr12:38710504 ALG10B -0.42 -6.14 -0.32 2.25e-9 Heart rate; LIHC cis rs8141529 0.509 rs5762863 chr22:29253335 A/C cg15103426 chr22:29168792 CCDC117 0.66 10.36 0.49 4.77e-22 Lymphocyte counts; LIHC cis rs6546537 0.714 rs17036759 chr2:69767029 C/T cg10773587 chr2:69614142 GFPT1 -0.54 -7.67 -0.38 1.78e-13 Serum thyroid-stimulating hormone levels; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg06873352 chr17:61820015 STRADA 0.74 13.27 0.58 1.02e-32 Prudent dietary pattern; LIHC cis rs7086627 0.515 rs2125040 chr10:82208422 G/C cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18579396 chr17:41623924 ETV4 0.51 7.01 0.35 1.26e-11 Lung function (FEV1/FVC); LIHC cis rs36051895 0.623 rs10975024 chr9:5246403 A/T cg02405213 chr9:5042618 JAK2 -0.58 -9.4 -0.45 8.19e-19 Pediatric autoimmune diseases; LIHC cis rs3806843 0.741 rs4912597 chr5:140106857 C/G cg16179182 chr5:140090404 VTRNA1-1 0.36 5.84 0.3 1.22e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs6582630 0.537 rs1949610 chr12:38387838 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.4 0.41 1.23e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs1949733 0.628 rs1543246 chr4:8504909 A/T cg11789530 chr4:8429930 ACOX3 0.69 10.48 0.49 1.74e-22 Response to antineoplastic agents; LIHC cis rs55823223 0.503 rs9906971 chr17:73848477 A/G cg14829360 chr17:73884958 NA -0.52 -7.83 -0.39 5.99e-14 Psoriasis; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg20990694 chr7:150417431 GIMAP1 0.35 6.08 0.31 3.24e-9 Immature fraction of reticulocytes; LIHC cis rs10744422 0.800 rs6489240 chr12:123275030 T/C cg07706471 chr12:123319906 HIP1R -0.57 -7.33 -0.37 1.71e-12 Schizophrenia; LIHC cis rs10744422 0.748 rs1671688 chr12:123255733 A/T cg07706471 chr12:123319906 HIP1R -0.57 -7.36 -0.37 1.36e-12 Schizophrenia; LIHC cis rs7582180 0.629 rs34745556 chr2:100942506 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs7224737 0.789 rs8071235 chr17:40300126 C/A cg20291162 chr17:40259547 DHX58 -0.41 -6.47 -0.33 3.34e-10 Fibrinogen levels; LIHC cis rs912057 0.526 rs201061 chr6:6730512 C/T cg06612196 chr6:6737390 NA -0.46 -8.81 -0.43 6.34e-17 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC trans rs2211698 0.881 rs2070360 chr21:35826828 T/A cg18044562 chr7:50468399 IKZF1 0.44 6.77 0.34 5.59e-11 Cancer; LIHC cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg08392591 chr16:89556376 ANKRD11 0.54 8.64 0.42 2.18e-16 Multiple myeloma (IgH translocation); LIHC cis rs4407350 0.837 rs5765707 chr22:44909507 A/T cg04154583 chr22:44889756 LDOC1L 0.3 5.86 0.3 1.09e-8 Intelligence (multi-trait analysis); LIHC cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg06138931 chr13:21896616 NA 0.51 8.7 0.43 1.42e-16 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6963495 0.818 rs73192126 chr7:105175415 T/C cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs5769707 0.967 rs2071904 chr22:50034477 C/T cg07959070 chr22:50026188 C22orf34 -0.34 -8.76 -0.43 9.09e-17 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1448094 0.512 rs7134732 chr12:86241908 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs4631830 0.720 rs2012677 chr10:51504797 T/A cg20129853 chr10:51489980 NA -0.39 -8.51 -0.42 5.5e-16 Prostate-specific antigen levels; LIHC cis rs8141529 0.600 rs16986838 chr22:29312578 C/T cg15103426 chr22:29168792 CCDC117 0.43 6.05 0.31 3.85e-9 Lymphocyte counts; LIHC cis rs11864453 0.647 rs8043606 chr16:72135319 T/C cg16558253 chr16:72132732 DHX38 -0.41 -6.6 -0.34 1.61e-10 Fibrinogen levels; LIHC cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.15 -0.48 2.43e-21 Platelet count; LIHC cis rs7772486 0.558 rs2142978 chr6:146012061 T/C cg13319975 chr6:146136371 FBXO30 0.55 8.69 0.43 1.49e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg11062466 chr8:58055876 NA -0.48 -6.88 -0.35 2.83e-11 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.903 rs61830933 chr10:934195 G/A cg20503657 chr10:835505 NA 1.32 14.2 0.61 2.75e-36 Eosinophil percentage of granulocytes; LIHC cis rs9788682 1.000 rs12441426 chr15:78812329 T/C cg06917634 chr15:78832804 PSMA4 -0.51 -7.25 -0.37 2.74e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs17253792 0.915 rs28375514 chr14:56179941 G/A cg01858014 chr14:56050164 KTN1 -0.76 -8.08 -0.4 1.1e-14 Putamen volume; LIHC cis rs35110281 0.776 rs2838316 chr21:44990036 C/T cg01579765 chr21:45077557 HSF2BP -0.36 -6.85 -0.35 3.47e-11 Mean corpuscular volume; LIHC cis rs1008375 1.000 rs3846357 chr4:17635887 A/T cg16339924 chr4:17578868 LAP3 0.45 6.3 0.32 9.35e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs72781680 0.716 rs17045975 chr2:24099611 A/T cg08917208 chr2:24149416 ATAD2B -0.61 -6.27 -0.32 1.07e-9 Lymphocyte counts; LIHC cis rs798554 0.660 rs2527687 chr7:2838485 G/A cg19717773 chr7:2847554 GNA12 -0.42 -7.43 -0.37 8.77e-13 Height; LIHC cis rs722599 0.683 rs8014695 chr14:75301617 C/G cg11812906 chr14:75593930 NEK9 0.43 6.58 0.34 1.81e-10 IgG glycosylation; LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg00800038 chr16:89945340 TCF25 0.59 9.69 0.46 9.12e-20 Skin colour saturation; LIHC cis rs1008375 1.000 rs2159583 chr4:17658838 T/C cg16339924 chr4:17578868 LAP3 0.44 6.18 0.32 1.78e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs782590 0.934 rs17369191 chr2:55757885 T/C cg18811423 chr2:55921094 PNPT1 0.97 15.08 0.63 9.28e-40 Metabolic syndrome; LIHC cis rs11763147 1 rs11763147 chr7:65326821 C/T cg00343986 chr7:65444356 GUSB -0.43 -5.92 -0.3 8e-9 Corneal structure; LIHC cis rs7224685 0.530 rs7221574 chr17:4007543 T/C cg11204139 chr17:3907470 NA 0.56 6.69 0.34 9.15e-11 Type 2 diabetes; LIHC cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2075371 1.000 rs2075372 chr7:133984432 C/T cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC cis rs8038465 0.622 rs62004587 chr15:73859016 A/C cg15420318 chr15:73925796 NPTN 0.51 7.65 0.38 2.11e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2303759 0.676 rs10426452 chr19:49907690 G/A cg22307029 chr19:49891270 CCDC155 0.59 9.57 0.46 2.2e-19 Multiple sclerosis; LIHC cis rs916888 0.773 rs199451 chr17:44801784 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.96 0.35 1.74e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7659604 0.521 rs4833232 chr4:122684367 C/T cg19671926 chr4:122722719 EXOSC9 0.54 8.36 0.41 1.6e-15 Type 2 diabetes; LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.8 0.8 1.96e-78 Prudent dietary pattern; LIHC cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg20295408 chr7:1910781 MAD1L1 0.43 6.03 0.31 4.22e-9 Bipolar disorder and schizophrenia; LIHC cis rs11779988 0.516 rs426498 chr8:17897158 T/C cg04898035 chr8:17640624 MTUS1 -0.33 -5.76 -0.3 1.85e-8 Breast cancer; LIHC cis rs66573146 0.539 rs56659624 chr4:7069377 G/C cg06697600 chr4:7070879 GRPEL1 0.76 9.26 0.45 2.39e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs2070488 1.000 rs2070488 chr3:38442490 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.92 -16.02 -0.65 1.68e-43 Electrocardiographic conduction measures; LIHC cis rs12477438 0.501 rs6708878 chr2:99801564 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs11785400 1.000 rs7002932 chr8:143738816 C/A cg24634471 chr8:143751801 JRK 0.52 8.36 0.41 1.55e-15 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00734800 chr3:50388182 TUSC4;CYB561D2 0.37 6.35 0.32 6.98e-10 Cognitive function; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg07677032 chr17:61819896 STRADA 0.44 6.5 0.33 2.88e-10 Prudent dietary pattern; LIHC cis rs6882046 0.513 rs616391 chr5:88038845 C/T cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC trans rs2243480 1.000 rs419603 chr7:65597341 C/T cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs11098499 1.000 rs13116504 chr4:120209412 A/C cg09307838 chr4:120376055 NA 0.72 10.69 0.5 3.3e-23 Corneal astigmatism; LIHC cis rs858239 0.670 rs3807452 chr7:23162081 C/T cg23682824 chr7:23144976 KLHL7 -0.39 -5.92 -0.3 7.75e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs10276381 0.579 rs73072539 chr7:28146255 C/G cg23620719 chr7:28220237 JAZF1 0.63 7.04 0.36 1.05e-11 Crohn's disease; LIHC cis rs7208859 0.673 rs216424 chr17:28943064 T/G cg13385521 chr17:29058706 SUZ12P 0.59 5.86 0.3 1.09e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4925386 1.000 rs4925382 chr20:60918542 G/C cg06026331 chr20:60912101 LAMA5 -0.51 -8.61 -0.42 2.8e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs1997103 0.954 rs2177807 chr7:55391002 G/T cg17469321 chr7:55412551 NA -0.46 -6.75 -0.34 6.23e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs600806 0.713 rs10857786 chr1:110010110 C/G cg16275483 chr1:110013120 SYPL2 -0.49 -6.15 -0.32 2.16e-9 Intelligence (multi-trait analysis); LIHC cis rs2439831 1.000 rs690263 chr15:43704465 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.66 9.15 0.44 5.41e-18 Lung cancer in ever smokers; LIHC cis rs9814567 0.929 rs9838834 chr3:134207077 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.37 -0.56 2.66e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg26818010 chr10:134567672 INPP5A -0.7 -8.68 -0.43 1.59e-16 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg17427986 chr1:154402922 IL6R 0.49 6.93 0.35 2.17e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg00149659 chr3:10157352 C3orf10 0.64 6.95 0.35 1.88e-11 Alzheimer's disease; LIHC cis rs17685 0.712 rs1639620 chr7:75704090 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7534824 0.625 rs17409499 chr1:101504936 C/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.21 0.36 3.58e-12 Refractive astigmatism; LIHC cis rs6430585 0.583 rs3087343 chr2:136622543 T/G cg15123519 chr2:136567270 LCT -0.37 -5.87 -0.3 1.05e-8 Corneal structure; LIHC cis rs7503168 0.730 rs11655803 chr17:33952696 T/C cg20932281 chr17:33905541 PEX12 0.54 7.01 0.35 1.25e-11 Plateletcrit; LIHC cis rs8180040 0.966 rs11716763 chr3:47518266 C/T cg16586182 chr3:47516702 SCAP 0.61 12.05 0.55 3.96e-28 Colorectal cancer; LIHC cis rs75908454 1.000 rs117712749 chr6:169836055 C/T cg19338460 chr6:170058176 WDR27 -0.86 -7.77 -0.39 9.33e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs2073300 0.609 rs6132617 chr20:23420151 G/C cg12062639 chr20:23401060 NAPB 1.01 13.1 0.58 4.73e-32 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11931598 1.000 rs11931598 chr4:7047102 A/G cg02503808 chr4:7069936 GRPEL1 0.39 5.92 0.3 8.03e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs13217239 0.646 rs10946891 chr6:26973215 T/C cg18867708 chr6:26865862 GUSBL1 0.52 8.1 0.4 9.8e-15 Schizophrenia; LIHC cis rs644799 0.544 rs555556 chr11:95618425 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.59 9.2 0.45 3.49e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2153535 0.580 rs7742689 chr6:8452433 C/A cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg25388301 chr11:62439134 C11orf83;C11orf48 -0.52 -6.24 -0.32 1.27e-9 Lung function (FEV1); LIHC cis rs6448317 0.556 rs4697495 chr4:24907501 A/G cg21108841 chr4:24914750 CCDC149 0.53 6.57 0.33 1.92e-10 Heschl's gyrus morphology; LIHC cis rs1029738 0.615 rs3757447 chr7:22894735 A/T cg22407942 chr7:22894828 SNORD93 -0.34 -6.48 -0.33 3.12e-10 Fibrinogen levels; LIHC cis rs7927592 0.913 rs7925275 chr11:68290433 T/C cg20283391 chr11:68216788 NA -0.51 -7.49 -0.38 5.98e-13 Total body bone mineral density; LIHC cis rs9733 0.596 rs2867300 chr1:150666990 C/G cg18016565 chr1:150552671 MCL1 0.6 11.8 0.54 3.46e-27 Tonsillectomy; LIHC cis rs4934494 0.681 rs1129777 chr10:91468925 C/G cg19698084 chr10:91461284 KIF20B -0.47 -6.35 -0.32 6.84e-10 Red blood cell count; LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.7 -11.39 -0.52 1.04e-25 Prudent dietary pattern; LIHC cis rs16870629 0.567 rs35661060 chr5:1060379 G/A cg00278107 chr5:1061253 SLC12A7 0.96 17.59 0.69 8.46e-50 QT interval; LIHC cis rs2180341 1.000 rs13218061 chr6:127653758 G/A cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs477692 0.673 rs556253 chr10:131355781 G/A cg05714579 chr10:131428358 MGMT 0.39 6.24 0.32 1.26e-9 Response to temozolomide; LIHC cis rs1707322 1.000 rs6672115 chr1:46272879 T/C cg03146154 chr1:46216737 IPP 0.48 7.57 0.38 3.46e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7131987 0.683 rs12366505 chr12:29474110 C/T cg16970926 chr12:29381810 FAR2 0.28 5.97 0.31 6.02e-9 QT interval; LIHC cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg10360323 chr17:41437877 NA 0.4 5.99 0.31 5.19e-9 Menopause (age at onset); LIHC cis rs11098499 1.000 rs6849889 chr4:120186348 A/C cg09307838 chr4:120376055 NA 0.71 10.49 0.49 1.63e-22 Corneal astigmatism; LIHC cis rs1005277 0.529 rs1780125 chr10:38531376 A/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.08 -0.44 8.66e-18 Extrinsic epigenetic age acceleration; LIHC cis rs5769765 0.825 rs9616780 chr22:50292763 T/C cg26441486 chr22:50317300 CRELD2 0.36 6.38 0.33 5.73e-10 Schizophrenia; LIHC cis rs651907 0.557 rs11720745 chr3:101441690 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.4 0.52 9.54e-26 Colorectal cancer; LIHC cis rs896854 0.517 rs1011796 chr8:95951273 A/G cg16049864 chr8:95962084 TP53INP1 0.47 7.66 0.38 1.95e-13 Type 2 diabetes; LIHC cis rs722599 0.683 rs10144860 chr14:75286426 T/C cg11812906 chr14:75593930 NEK9 0.42 6.47 0.33 3.47e-10 IgG glycosylation; LIHC cis rs68170813 0.559 rs80153759 chr7:106944145 C/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs858239 0.600 rs7456915 chr7:23143049 T/C cg23682824 chr7:23144976 KLHL7 0.45 6.79 0.34 5e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs7772486 0.790 rs2253768 chr6:146199922 A/G cg05347473 chr6:146136440 FBXO30 0.37 6.08 0.31 3.14e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769707 0.604 rs1018814 chr22:50036900 T/C cg01652190 chr22:50026171 C22orf34 -0.34 -7.53 -0.38 4.66e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1707322 1.000 rs785465 chr1:46522577 G/T cg03146154 chr1:46216737 IPP 0.45 7.37 0.37 1.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7197653 0.519 rs55757091 chr16:68323654 G/A cg05110241 chr16:68378359 PRMT7 -0.68 -7.49 -0.38 5.88e-13 Magnesium levels; LIHC trans rs1814175 0.616 rs1794131 chr11:49904194 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs12765878 1.000 rs10883942 chr10:105651386 A/G cg11005552 chr10:105648138 OBFC1 0.39 6.26 0.32 1.12e-9 Coronary artery disease; LIHC cis rs1499614 1.000 rs1267818 chr7:66107024 C/T cg18252515 chr7:66147081 NA -1.33 -17.89 -0.7 5.71e-51 Gout; LIHC cis rs921968 0.541 rs2710246 chr2:219533894 C/T cg02176678 chr2:219576539 TTLL4 0.5 7.38 0.37 1.18e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs600806 0.888 rs652651 chr1:109844532 A/G cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.73 -0.3 2.21e-8 Intelligence (multi-trait analysis); LIHC cis rs9596863 0.898 rs35732706 chr13:54343886 T/G ch.13.53330881F chr13:54432880 NA 0.45 6.16 0.32 2.06e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs644799 0.862 rs1150361 chr11:95633805 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.62 8.51 0.42 5.55e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.86 0.63 6.95e-39 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs11122280 chr1:231519816 T/C cg06096015 chr1:231504339 EGLN1 0.48 8.76 0.43 9.48e-17 Hemoglobin concentration; LIHC cis rs6141769 0.542 rs7360824 chr20:31315158 A/G cg13636640 chr20:31349939 DNMT3B -0.32 -5.74 -0.3 2.08e-8 Subjective well-being; LIHC cis rs6500602 0.727 rs2160567 chr16:4535557 C/T cg08645402 chr16:4508243 NA 0.43 8.1 0.4 9.52e-15 Schizophrenia; LIHC cis rs6061231 1.000 rs67941642 chr20:60958108 C/T cg03945807 chr20:60948434 NA 0.4 6.5 0.33 2.86e-10 Colorectal cancer; LIHC cis rs9733 0.596 rs1415148 chr1:150705755 G/A cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs1499614 1.000 rs1882655 chr7:66147057 T/C cg18252515 chr7:66147081 NA 1.34 18.69 0.71 3.43e-54 Gout; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs16958440 1.000 rs2289130 chr18:44626630 T/G cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC cis rs2839186 0.814 rs12482209 chr21:47664275 C/G cg11766577 chr21:47581405 C21orf56 0.42 6.77 0.34 5.73e-11 Testicular germ cell tumor; LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.21 0.55 1.06e-28 Prudent dietary pattern; LIHC cis rs7224737 1.000 rs7224737 chr17:40289364 A/G cg02450064 chr17:40260053 DHX58 0.28 5.99 0.31 5.19e-9 Fibrinogen levels; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs870825 0.587 rs7682995 chr4:185640684 G/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs6502050 0.835 rs8078795 chr17:80126320 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs6545883 1.000 rs6545883 chr2:61772257 A/G cg15711740 chr2:61764176 XPO1 -0.45 -6.31 -0.32 8.58e-10 Tuberculosis; LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg04234412 chr22:24373322 LOC391322 -0.71 -10.97 -0.51 3.4e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3768617 0.510 rs4651143 chr1:183097398 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.57e-22 Fuchs's corneal dystrophy; LIHC cis rs9911578 1.000 rs654778 chr17:56736473 A/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC trans rs2243480 1.000 rs73142162 chr7:65374296 A/T cg10756647 chr7:56101905 PSPH 1.1 13.21 0.58 1.86e-32 Diabetic kidney disease; LIHC cis rs2463822 1.000 rs2463821 chr11:62111662 T/C cg06239285 chr11:62104954 ASRGL1 0.97 7.09 0.36 7.81e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC trans rs11157436 0.918 rs11157427 chr14:22622247 T/G cg13567813 chr19:50879636 NR1H2 0.41 6.11 0.31 2.77e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg05564831 chr3:52568323 NT5DC2 0.38 6.09 0.31 3.1e-9 Bipolar disorder; LIHC cis rs7584330 0.628 rs73098849 chr2:238389739 G/A cg08992911 chr2:238395768 MLPH 0.52 6.0 0.31 5e-9 Prostate cancer; LIHC cis rs61990749 0.597 rs12887606 chr14:78200620 G/A cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.81 -0.39 7.3e-14 Fibroblast growth factor basic levels; LIHC cis rs4970988 0.787 rs1532770 chr1:150725335 G/T cg18016565 chr1:150552671 MCL1 0.56 10.67 0.5 3.76e-23 Urate levels; LIHC cis rs4407350 1.000 rs5765745 chr22:44924894 A/G cg11695653 chr22:44894386 LDOC1L -0.35 -5.73 -0.3 2.21e-8 Intelligence (multi-trait analysis); LIHC cis rs2274273 1.000 rs72718804 chr14:55630610 G/A cg01864836 chr14:55583639 NA -0.36 -6.09 -0.31 3.02e-9 Protein biomarker; LIHC cis rs7116495 1.000 rs2511075 chr11:71780257 T/C cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs2834215 0.753 rs9976794 chr21:34868143 T/A cg14850771 chr21:34775459 IFNGR2 0.42 6.07 0.31 3.39e-9 Crohn's disease; LIHC cis rs4555082 0.957 rs3000073 chr14:105729792 G/A cg13114125 chr14:105738426 BRF1 -0.7 -9.6 -0.46 1.75e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs3110496 0.750 rs497993 chr17:27895528 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.45 5.82 0.3 1.37e-8 Height; LIHC cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg06618935 chr21:46677482 NA -0.31 -5.92 -0.3 7.85e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4663866 1.000 rs34897410 chr2:239182123 T/C cg16914508 chr2:239161102 PER2 0.8 5.9 0.3 8.86e-9 Irritable bowel syndrome; LIHC cis rs77633900 0.772 rs157778 chr15:76759444 G/C cg21673338 chr15:77095150 SCAPER -0.52 -6.11 -0.31 2.78e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg06656553 chr16:89960601 TCF25 -0.5 -6.47 -0.33 3.34e-10 Skin colour saturation; LIHC cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg12463550 chr7:65579703 CRCP 0.68 7.14 0.36 5.69e-12 Diabetic kidney disease; LIHC cis rs2370759 0.945 rs74625866 chr10:32597618 A/T cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs1707322 0.752 rs8179296 chr1:46143791 G/A cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.38e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7659604 0.605 rs2071486 chr4:122740162 C/T cg19748678 chr4:122722346 EXOSC9 0.53 8.85 0.43 4.92e-17 Type 2 diabetes; LIHC cis rs3770081 1.000 rs77621359 chr2:86330353 A/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.44 6.11 0.31 2.74e-9 Facial emotion recognition (sad faces); LIHC cis rs3762637 0.823 rs59569049 chr3:122238788 A/T cg24169773 chr3:122142474 KPNA1 -0.46 -9.0 -0.44 1.54e-17 LDL cholesterol levels; LIHC cis rs2832191 0.716 rs9983051 chr21:30371890 C/T cg08807101 chr21:30365312 RNF160 0.79 11.98 0.54 7.34e-28 Dental caries; LIHC cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg02290350 chr8:58132656 NA 0.48 9.92 0.47 1.54e-20 Developmental language disorder (linguistic errors); LIHC cis rs67460515 0.892 rs4856757 chr3:160999418 A/T cg17135325 chr3:160939158 NMD3 0.55 7.83 0.39 6.04e-14 Parkinson's disease; LIHC cis rs904251 0.523 rs1776455 chr6:37482923 A/T cg01843034 chr6:37503916 NA -0.45 -7.79 -0.39 8.01e-14 Cognitive performance; LIHC cis rs12579753 1.000 rs11613196 chr12:82173251 A/T cg07988820 chr12:82153109 PPFIA2 0.47 5.91 0.3 8.23e-9 Resting heart rate; LIHC cis rs2832191 1.000 rs2832190 chr21:30488226 G/A cg24692254 chr21:30365293 RNF160 -0.64 -11.4 -0.52 9.9e-26 Dental caries; LIHC cis rs5769707 0.967 rs4524218 chr22:50018639 G/A cg01652190 chr22:50026171 C22orf34 -0.31 -7.15 -0.36 5.15e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1008375 0.931 rs6449309 chr4:17573208 C/T cg16339924 chr4:17578868 LAP3 0.59 7.4 0.37 1.08e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03744954 chr7:23637556 CCDC126 -0.42 -6.37 -0.33 6.08e-10 Cognitive function; LIHC cis rs738322 0.935 rs75387 chr22:38572057 C/T cg25457927 chr22:38595422 NA -0.27 -6.61 -0.34 1.51e-10 Cutaneous nevi; LIHC cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg03396347 chr1:1875803 NA -0.47 -8.72 -0.43 1.24e-16 Body mass index; LIHC cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg24531977 chr5:56204891 C5orf35 -0.57 -8.23 -0.41 4.06e-15 Initial pursuit acceleration; LIHC cis rs367615 0.591 rs4530812 chr5:108858587 A/C cg17395555 chr5:108820864 NA -0.28 -5.98 -0.31 5.62e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs7095607 0.606 rs10998014 chr10:69959567 C/A cg18986048 chr10:69913749 MYPN 0.39 5.95 0.31 6.77e-9 Lung function (FVC); LIHC cis rs1801251 0.893 rs11687128 chr2:233608901 T/C cg08000102 chr2:233561755 GIGYF2 0.76 11.47 0.53 5.31e-26 Coronary artery disease; LIHC cis rs7592578 0.581 rs59109438 chr2:191287683 A/G cg27211696 chr2:191398769 TMEM194B -0.49 -6.45 -0.33 3.85e-10 Diastolic blood pressure; LIHC cis rs2070488 0.775 rs13098946 chr3:38517784 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.53 0.56 6.83e-30 Electrocardiographic conduction measures; LIHC trans rs9834975 0.544 rs12485294 chr3:122285005 G/A cg18228109 chr6:162684441 PARK2 0.34 6.06 0.31 3.56e-9 Diastolic blood pressure; LIHC cis rs74233809 1.000 rs11191575 chr10:104898337 C/T cg03493300 chr10:104813866 CNNM2 0.47 6.3 0.32 9.19e-10 Birth weight; LIHC cis rs2997447 0.846 rs3008234 chr1:26405458 A/G cg19633962 chr1:26362018 EXTL1 -0.63 -5.85 -0.3 1.17e-8 QRS complex (12-leadsum); LIHC cis rs6001982 0.541 rs55775429 chr22:41049460 A/G cg14879645 chr22:41048474 NA 0.4 5.82 0.3 1.35e-8 Breast cancer; LIHC cis rs2832191 0.791 rs2832181 chr21:30481371 G/T cg08807101 chr21:30365312 RNF160 -0.64 -10.0 -0.48 8.22e-21 Dental caries; LIHC cis rs3741404 0.574 rs616563 chr11:63877501 G/C cg18225595 chr11:63971243 STIP1 0.45 6.96 0.35 1.69e-11 Platelet count; LIHC cis rs2599510 0.693 rs2754514 chr2:32788836 T/A cg02381751 chr2:32503542 YIPF4 0.48 6.47 0.33 3.41e-10 Interleukin-18 levels; LIHC cis rs11229555 0.645 rs10466679 chr11:58188257 T/C cg15696309 chr11:58395628 NA -0.64 -7.36 -0.37 1.39e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2228479 0.717 rs2286392 chr16:89809549 A/G cg00800038 chr16:89945340 TCF25 -0.61 -9.38 -0.45 9.24e-19 Skin colour saturation; LIHC cis rs7119 0.717 rs10519167 chr15:77723027 G/T cg17802220 chr15:77601643 NA -0.41 -6.98 -0.35 1.51e-11 Type 2 diabetes; LIHC cis rs35306767 0.807 rs34527494 chr10:935192 T/C cg20503657 chr10:835505 NA 1.32 14.2 0.61 2.75e-36 Eosinophil percentage of granulocytes; LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg02711726 chr17:80685570 FN3KRP -0.42 -7.66 -0.38 1.98e-13 Glycated hemoglobin levels; LIHC cis rs1941023 0.503 rs10750936 chr11:60144180 G/A cg08716584 chr11:60157161 MS4A7 -0.35 -8.03 -0.4 1.58e-14 Congenital heart disease (maternal effect); LIHC cis rs10883723 0.962 rs1056738 chr10:104236481 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 11.37 0.52 1.22e-25 Allergic disease (asthma, hay fever or eczema); LIHC cis rs986417 0.901 rs1950313 chr14:60997782 A/G cg27398547 chr14:60952738 C14orf39 0.7 8.03 0.4 1.56e-14 Gut microbiota (bacterial taxa); LIHC cis rs4727027 0.933 rs28767030 chr7:148825918 T/G cg23583168 chr7:148888333 NA -0.73 -10.26 -0.49 1.02e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7829975 0.714 rs4841042 chr8:8664622 A/G cg06636001 chr8:8085503 FLJ10661 -0.4 -6.73 -0.34 7.33e-11 Mood instability; LIHC trans rs9747201 1.000 rs62078307 chr17:80090053 G/T cg07393940 chr7:158741817 NA -0.57 -6.8 -0.35 4.81e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1707322 0.716 rs6694889 chr1:46101806 A/C cg03146154 chr1:46216737 IPP 0.56 9.53 0.46 3.1e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs992157 0.717 rs11692780 chr2:219149163 A/G cg00012203 chr2:219082015 ARPC2 -0.82 -13.02 -0.58 9.36e-32 Colorectal cancer; LIHC cis rs921968 0.565 rs4674330 chr2:219595710 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs8017423 0.967 rs57793584 chr14:90714833 G/A cg04374321 chr14:90722782 PSMC1 0.75 14.54 0.62 1.23e-37 Mortality in heart failure; LIHC cis rs6831256 1.000 rs10007119 chr4:3473066 A/G cg15867164 chr4:3464754 DOK7 -0.42 -7.26 -0.37 2.59e-12 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs55665837 0.540 rs10832299 chr11:14769392 G/A cg25251204 chr11:14927456 NA 0.41 5.79 0.3 1.56e-8 Vitamin D levels; LIHC cis rs918629 0.679 rs58921760 chr5:95270865 A/C cg10483112 chr5:95245456 ELL2 -0.37 -6.34 -0.32 7.39e-10 IgG glycosylation; LIHC cis rs963731 0.649 rs297149 chr2:39324469 G/C cg04010122 chr2:39346883 SOS1 -0.7 -6.27 -0.32 1.08e-9 Corticobasal degeneration; LIHC cis rs61990749 0.597 rs176952 chr14:78180736 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.62 10.32 0.49 6.7e-22 Fibroblast growth factor basic levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04817870 chr17:79963651 ASPSCR1 0.4 6.05 0.31 3.79e-9 Longevity; LIHC cis rs7249142 0.506 rs8101388 chr19:19293938 A/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.4 -6.71 -0.34 8.13e-11 IgG glycosylation; LIHC cis rs7178375 1.000 rs7178533 chr15:31215976 C/G cg19680485 chr15:31195859 MTMR15 -0.55 -5.98 -0.31 5.64e-9 Hypertriglyceridemia; LIHC cis rs7216064 1.000 rs12602655 chr17:65909442 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.29 -0.45 1.89e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs10870270 1.000 rs7098014 chr10:133775029 G/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.79 -0.57 7.03e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg11764359 chr7:65958608 NA -0.57 -5.95 -0.31 6.6e-9 Diabetic kidney disease; LIHC cis rs921968 0.541 rs7604319 chr2:219538799 A/C cg02985541 chr2:219472218 PLCD4 -0.39 -5.94 -0.31 7.1e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.817 rs7950856 chr11:49976394 C/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs7119038 0.865 rs10892299 chr11:118726843 C/T cg19308663 chr11:118741387 NA 0.46 6.01 0.31 4.8e-9 Sjögren's syndrome; LIHC cis rs7208859 0.623 rs9912440 chr17:29148772 A/G cg14067834 chr17:29058358 SUZ12P 0.63 6.38 0.33 5.64e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg15691649 chr6:25882328 NA 0.41 6.06 0.31 3.51e-9 Blood metabolite levels; LIHC cis rs7659604 0.502 rs4516738 chr4:122669177 T/C cg19671926 chr4:122722719 EXOSC9 0.46 6.68 0.34 9.6e-11 Type 2 diabetes; LIHC cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.11 -16.98 -0.68 2.53e-47 Gut microbiome composition (summer); LIHC cis rs367615 0.679 rs11241021 chr5:108812090 T/G cg17395555 chr5:108820864 NA 0.39 8.56 0.42 3.9e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs477692 0.629 rs945231 chr10:131294827 A/G cg05714579 chr10:131428358 MGMT 0.38 6.1 0.31 2.94e-9 Response to temozolomide; LIHC cis rs1707322 0.964 rs6697830 chr1:46290477 C/A cg06784218 chr1:46089804 CCDC17 0.35 6.38 0.33 5.9e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9399135 0.967 rs6919862 chr6:135352443 C/A cg24558204 chr6:135376177 HBS1L 0.43 7.11 0.36 6.62e-12 Red blood cell count; LIHC cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.57 -0.46 2.15e-19 Initial pursuit acceleration; LIHC cis rs9660992 0.762 rs1172129 chr1:205244972 T/A cg21545522 chr1:205238299 TMCC2 0.29 5.93 0.31 7.36e-9 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2629751 0.512 rs2723868 chr12:104422317 C/T cg14987745 chr12:104360022 TDG -0.69 -6.84 -0.35 3.6e-11 Hepatitis C induced liver fibrosis; LIHC cis rs35110281 0.667 rs2070533 chr21:45122753 G/A cg21573476 chr21:45109991 RRP1B -0.53 -10.18 -0.48 1.91e-21 Mean corpuscular volume; LIHC cis rs11148252 0.574 rs3742297 chr13:53278067 T/C cg02158880 chr13:53174818 NA 0.37 5.81 0.3 1.47e-8 Lewy body disease; LIHC trans rs2235573 0.527 rs139883 chr22:38369027 C/T cg19894588 chr14:64061835 NA 0.49 6.59 0.34 1.69e-10 Glioblastoma;Glioma; LIHC cis rs7552404 1.000 rs4949875 chr1:76173080 G/A cg03433033 chr1:76189801 ACADM 0.67 9.35 0.45 1.16e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6076065 0.707 rs1419007 chr20:23336895 T/C cg11657817 chr20:23433608 CST11 0.31 6.66 0.34 1.12e-10 Facial morphology (factor 15, philtrum width); LIHC cis rs6964587 0.869 rs401 chr7:91527945 T/G cg17063962 chr7:91808500 NA -0.98 -18.56 -0.71 1.1e-53 Breast cancer; LIHC cis rs7772486 0.790 rs9376968 chr6:146180364 T/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.86 -0.3 1.07e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4555082 0.874 rs2735828 chr14:105710486 C/A cg10792982 chr14:105748885 BRF1 0.43 5.98 0.31 5.54e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs2073300 0.609 rs17830281 chr20:23350525 C/T cg12062639 chr20:23401060 NAPB 1.08 14.49 0.62 1.89e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11628318 0.614 rs7155804 chr14:103114945 A/G cg01864069 chr14:103024347 NA 0.45 7.15 0.36 5.15e-12 Platelet count; LIHC cis rs10751667 0.643 rs6597969 chr11:928843 C/T ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC cis rs79149102 0.579 rs73438569 chr15:75354486 T/A cg15902774 chr15:75289873 SCAMP5 0.44 6.46 0.33 3.65e-10 Lung cancer; LIHC cis rs5769707 0.609 rs2071890 chr22:50001291 G/A cg01652190 chr22:50026171 C22orf34 -0.35 -7.98 -0.4 2.28e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9916302 0.904 rs10221223 chr17:37489100 T/G cg03013999 chr17:37608204 MED1 -0.35 -5.82 -0.3 1.38e-8 Glomerular filtration rate (creatinine); LIHC cis rs3849570 1.000 rs3772883 chr3:81802802 C/T cg07356753 chr3:81810745 GBE1 -0.59 -8.0 -0.4 1.98e-14 Waist circumference;Body mass index; LIHC cis rs7818382 1.000 rs7818382 chr8:96054000 C/T cg09323728 chr8:95962352 TP53INP1 -0.28 -6.08 -0.31 3.27e-9 Alzheimer's disease (late onset); LIHC cis rs11711311 1.000 rs10934243 chr3:113430239 T/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.44 8.54 0.42 4.53e-16 IgG glycosylation; LIHC cis rs9303280 0.901 rs7359623 chr17:38049589 C/T cg11212589 chr17:38028394 ZPBP2 0.37 7.51 0.38 5.25e-13 Self-reported allergy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27266822 chr1:16073415 TMEM82 0.41 6.49 0.33 2.94e-10 Cognitive function; LIHC cis rs6867032 1.000 rs4975802 chr5:2019750 T/C cg26168224 chr5:2018326 NA 0.3 7.38 0.37 1.19e-12 Gut microbiome composition (winter); LIHC cis rs2180341 1.000 rs7756336 chr6:127650299 T/C cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg05896524 chr21:47604654 C21orf56 0.45 6.8 0.35 4.58e-11 Testicular germ cell tumor; LIHC cis rs238295 0.766 rs6053517 chr20:5564774 T/C cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -6.93 -0.35 2.05e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs9910055 0.530 rs11652651 chr17:42302907 A/G cg19774624 chr17:42201019 HDAC5 0.57 8.07 0.4 1.17e-14 Total body bone mineral density; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC cis rs78456975 1.000 rs13413096 chr2:1553588 G/A cg01028140 chr2:1542097 TPO -0.53 -6.34 -0.32 7.32e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs28374715 0.681 rs7165396 chr15:41586947 T/C cg18705301 chr15:41695430 NDUFAF1 -1.21 -16.77 -0.67 1.76e-46 Ulcerative colitis; LIHC cis rs2257205 0.667 rs28363312 chr17:56788293 C/A cg12560992 chr17:57184187 TRIM37 0.72 7.97 0.4 2.33e-14 Pancreatic cancer; LIHC trans rs80033912 0.713 rs7629936 chr3:49836707 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.6 8.73 0.43 1.11e-16 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg08392591 chr16:89556376 ANKRD11 0.56 8.97 0.44 1.92e-17 Multiple myeloma (IgH translocation); LIHC cis rs3736485 0.966 rs2124878 chr15:51906337 C/T cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.57e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4919087 0.715 rs8181326 chr10:98998195 G/A cg25902810 chr10:99078978 FRAT1 0.62 8.75 0.43 1e-16 Monocyte count; LIHC cis rs4820539 0.902 rs737846 chr22:23460669 A/G cg14186256 chr22:23484241 RTDR1 0.97 20.63 0.74 5.12e-62 Bone mineral density; LIHC cis rs7487075 0.578 rs12319162 chr12:46837914 T/C cg23829395 chr12:46796953 NA 0.34 6.05 0.31 3.81e-9 Itch intensity from mosquito bite; LIHC cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg03517284 chr6:25882590 NA 0.84 11.44 0.53 7.07e-26 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18986451 chr3:100428869 TFG 0.45 7.25 0.36 2.81e-12 Pancreatic cancer; LIHC cis rs2236918 0.643 rs1776139 chr1:242027363 T/G cg17736920 chr1:242011382 EXO1 0.39 5.77 0.3 1.79e-8 Menopause (age at onset); LIHC cis rs9517320 0.515 rs9556969 chr13:99195948 T/C cg20487152 chr13:99095054 FARP1 -0.38 -6.29 -0.32 9.88e-10 Longevity; LIHC trans rs9951602 0.512 rs1599634 chr18:76643645 T/C cg02800362 chr5:177631904 HNRNPAB 0.64 10.24 0.48 1.24e-21 Obesity-related traits; LIHC cis rs4713118 0.513 rs156739 chr6:28013410 C/A cg23485639 chr6:28045615 ZNF165 0.38 5.9 0.3 8.99e-9 Parkinson's disease; LIHC cis rs17152411 1.000 rs12355869 chr10:126645231 G/T cg07906193 chr10:126599966 NA 0.49 7.77 0.39 9.18e-14 Height; LIHC cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg19318889 chr4:1322082 MAEA 0.47 6.43 0.33 4.23e-10 Obesity-related traits; LIHC cis rs2251381 0.778 rs2471947 chr21:30534219 G/T cg08807101 chr21:30365312 RNF160 0.75 9.84 0.47 2.86e-20 Selective IgA deficiency; LIHC trans rs12310956 0.532 rs7955514 chr12:33978737 G/A cg26384229 chr12:38710491 ALG10B 0.54 7.31 0.37 1.94e-12 Morning vs. evening chronotype; LIHC cis rs344364 0.511 rs12596510 chr16:1949480 G/A cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs1707322 1.000 rs11211244 chr1:46456673 G/A cg06784218 chr1:46089804 CCDC17 0.36 6.54 0.33 2.2e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10779751 1.000 rs2024627 chr1:11298790 T/C cg08854313 chr1:11322531 MTOR 0.8 11.24 0.52 3.72e-25 Body mass index; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg03509753 chr7:148922340 ZNF282 -0.37 -6.37 -0.33 6.13e-10 Pain; LIHC cis rs6088580 0.713 rs1884669 chr20:33171287 G/A cg08999081 chr20:33150536 PIGU 0.68 13.67 0.59 3.1e-34 Glomerular filtration rate (creatinine); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08663953 chr5:72804550 NA 0.48 6.31 0.32 8.52e-10 Hepatitis; LIHC cis rs12701220 0.725 rs13242971 chr7:1055515 C/T cg04498913 chr7:1135747 C7orf50 0.37 5.71 0.3 2.44e-8 Bronchopulmonary dysplasia; LIHC cis rs7534824 0.625 rs7514731 chr1:101449675 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 7.82 0.39 6.78e-14 Refractive astigmatism; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25300318 chr2:200527297 NA 0.43 6.52 0.33 2.6e-10 Bilirubin levels; LIHC cis rs9309473 0.950 rs6546859 chr2:73842055 C/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.73 -0.34 6.95e-11 Metabolite levels; LIHC cis rs2710642 0.721 rs1038572 chr2:62902019 G/T cg17519650 chr2:63277830 OTX1 0.51 7.19 0.36 4.12e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1949733 0.523 rs62287455 chr4:8544994 A/T cg11789530 chr4:8429930 ACOX3 -0.58 -8.08 -0.4 1.09e-14 Response to antineoplastic agents; LIHC cis rs7845219 0.539 rs13271644 chr8:95853948 A/G cg23172400 chr8:95962367 TP53INP1 -0.34 -7.2 -0.36 3.77e-12 Type 2 diabetes; LIHC cis rs7726839 0.561 rs11955068 chr5:582324 C/T cg09021430 chr5:549028 NA -0.4 -8.48 -0.42 6.68e-16 Obesity-related traits; LIHC cis rs77637988 0.578 rs11683099 chr2:48611519 A/T cg15846641 chr2:48541264 FOXN2 0.55 7.33 0.37 1.66e-12 Joint mobility (Beighton score); LIHC cis rs344364 0.511 rs1742472 chr16:1953040 A/G cg26897989 chr16:1907736 C16orf73 -0.49 -5.96 -0.31 6.16e-9 Glomerular filtration rate in chronic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25009504 chr18:21269793 LAMA3 0.42 6.1 0.31 2.82e-9 Lung function (FEV1/FVC); LIHC cis rs8044995 0.563 rs3743743 chr16:68397775 C/T cg09835421 chr16:68378352 PRMT7 -0.82 -9.6 -0.46 1.81e-19 Schizophrenia; LIHC cis rs6088580 0.634 rs6059851 chr20:33047945 G/A cg08999081 chr20:33150536 PIGU 0.67 13.32 0.58 6.74e-33 Glomerular filtration rate (creatinine); LIHC cis rs2404602 0.716 rs1588961 chr15:76752698 A/G cg03037974 chr15:76606532 NA 0.8 16.45 0.66 3.41e-45 Blood metabolite levels; LIHC cis rs798554 0.757 rs960273 chr7:2857876 T/C cg19524238 chr7:2802976 GNA12 -0.39 -5.8 -0.3 1.53e-8 Height; LIHC cis rs8072100 0.934 rs6504872 chr17:45438952 C/T cg25173405 chr17:45401733 C17orf57 -0.43 -5.88 -0.3 9.85e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.65 9.12 0.44 6.58e-18 Lymphocyte counts; LIHC cis rs10752881 1.000 rs10911185 chr1:182971747 G/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.34 0.49 5.68e-22 Colorectal cancer; LIHC cis rs7617773 0.743 rs4632568 chr3:48367819 C/T cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC trans rs9929218 0.551 rs2281850 chr16:68718750 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.93 -21.03 -0.75 1.3e-63 Colorectal cancer; LIHC cis rs9309473 0.948 rs7603647 chr2:73817238 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.56 -0.33 1.94e-10 Metabolite levels; LIHC cis rs6442522 0.560 rs924812 chr3:15516481 T/C cg16303742 chr3:15540471 COLQ 0.36 5.91 0.3 8.12e-9 Uric acid levels; LIHC cis rs875971 0.862 rs6964437 chr7:65686444 A/G cg18252515 chr7:66147081 NA 0.43 6.16 0.32 2.08e-9 Aortic root size; LIHC cis rs240764 0.711 rs240148 chr6:101076767 C/T cg09795085 chr6:101329169 ASCC3 0.51 7.16 0.36 4.85e-12 Neuroticism; LIHC cis rs4409675 0.576 rs6691656 chr1:28221130 C/G cg23691781 chr1:28212827 C1orf38 0.32 7.72 0.39 1.27e-13 Corneal astigmatism; LIHC cis rs10751667 0.643 rs7394524 chr11:933865 T/C cg11406765 chr11:980039 AP2A2 -0.35 -5.78 -0.3 1.69e-8 Alzheimer's disease (late onset); LIHC cis rs2976388 0.609 rs2717602 chr8:143805683 G/A cg13446199 chr8:143762866 PSCA -0.2 -5.85 -0.3 1.12e-8 Urinary tract infection frequency; LIHC cis rs9948 0.655 rs6576981 chr2:97394406 G/C cg01990225 chr2:97406019 LMAN2L -0.77 -6.44 -0.33 4.06e-10 Erectile dysfunction and prostate cancer treatment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09090048 chr11:134093731 VPS26B;NCAPD3 0.43 6.35 0.32 6.77e-10 Lung function (FEV1/FVC); LIHC cis rs600626 0.541 rs11236528 chr11:75469476 T/C cg24262691 chr11:75473276 NA 0.43 6.37 0.33 6e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs9372253 0.645 rs7753212 chr6:110700229 T/C cg00083206 chr6:110721305 DDO -0.34 -6.69 -0.34 9.39e-11 Platelet distribution width; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24229963 chr8:82633648 ZFAND1 0.4 6.17 0.32 1.91e-9 Cognitive function; LIHC trans rs7615952 0.608 rs35668111 chr3:125544635 C/T cg07211511 chr3:129823064 LOC729375 -0.49 -7.59 -0.38 3.02e-13 Blood pressure (smoking interaction); LIHC cis rs7312933 0.703 rs11181380 chr12:42616040 A/T cg17420585 chr12:42539391 GXYLT1 -0.38 -6.11 -0.31 2.66e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs7618501 0.633 rs7628058 chr3:50039474 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.57 9.17 0.44 4.36e-18 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.915 rs7314638 chr12:122983460 A/G cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.2 -0.41 4.94e-15 Body mass index; LIHC cis rs7903847 0.642 rs9888026 chr10:99159869 G/T cg20016023 chr10:99160130 RRP12 0.41 6.54 0.33 2.19e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9640161 0.789 rs4554381 chr7:150025567 G/A cg10018233 chr7:150070692 REPIN1 0.57 9.62 0.46 1.46e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs597539 0.652 rs622082 chr11:68703959 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.25 0.48 1.14e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs71386921 1 rs71386921 chr10:27478698 AAT/A cg14240646 chr10:27532245 ACBD5 -0.52 -5.85 -0.3 1.18e-8 Breast cancer; LIHC cis rs11098499 0.955 rs56386062 chr4:120155135 T/C cg09307838 chr4:120376055 NA 0.75 10.9 0.51 6e-24 Corneal astigmatism; LIHC trans rs877282 1.000 rs11253366 chr10:773386 C/T cg22713356 chr15:30763199 NA 1.23 10.89 0.51 6.83e-24 Uric acid levels; LIHC cis rs5769765 1.000 rs768619 chr22:50287266 C/T cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.25e-16 Schizophrenia; LIHC cis rs1401999 0.690 rs1402001 chr3:183642751 A/G cg05044414 chr3:183734942 ABCC5 0.32 6.06 0.31 3.7e-9 Anterior chamber depth; LIHC cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg12463550 chr7:65579703 CRCP 0.78 7.59 0.38 3.04e-13 Diabetic kidney disease; LIHC cis rs9467773 0.967 rs9295694 chr6:26512994 A/T cg09904177 chr6:26538194 HMGN4 0.66 13.89 0.6 4.28e-35 Intelligence (multi-trait analysis); LIHC cis rs1421811 0.606 rs10057069 chr5:32716589 A/G cg16267343 chr5:32710456 NPR3 0.6 6.28 0.32 1.01e-9 Blood pressure; LIHC cis rs9527 0.615 rs7080462 chr10:104736699 T/C cg15744005 chr10:104629667 AS3MT -0.3 -6.1 -0.31 2.9e-9 Arsenic metabolism; LIHC cis rs986417 0.688 rs965454 chr14:60960251 T/C cg27398547 chr14:60952738 C14orf39 0.77 9.25 0.45 2.58e-18 Gut microbiota (bacterial taxa); LIHC cis rs7107174 0.901 rs1055250 chr11:77925708 C/G cg02023728 chr11:77925099 USP35 0.48 9.06 0.44 1.02e-17 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg18252515 chr7:66147081 NA -1.24 -15.85 -0.65 7.92e-43 Diabetic kidney disease; LIHC cis rs6500602 0.727 rs4238849 chr16:4538114 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.95 0.31 6.47e-9 Schizophrenia; LIHC cis rs6088590 0.610 rs6120663 chr20:33081906 A/C cg24642439 chr20:33292090 TP53INP2 -0.59 -7.73 -0.39 1.25e-13 Coronary artery disease; LIHC cis rs611744 0.934 rs682954 chr8:109210559 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs1707322 1.000 rs11211205 chr1:46321874 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.6 -11.25 -0.52 3.3e-25 Prudent dietary pattern; LIHC cis rs11577318 0.579 rs35456934 chr1:26686864 G/A cg18121669 chr1:26560928 CCDC21 -0.5 -7.56 -0.38 3.72e-13 Granulocyte percentage of myeloid white cells; LIHC cis rs1816752 0.870 rs8000215 chr13:25009786 A/G cg02811702 chr13:24901961 NA 0.25 6.33 0.32 7.79e-10 Obesity-related traits; LIHC cis rs7502590 1.000 rs72854146 chr17:79078610 A/G cg02064366 chr17:79045526 BAIAP2 0.53 6.28 0.32 1.02e-9 Neuroticism; LIHC cis rs796364 1.000 rs166845 chr2:200823360 T/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.8 9.56 0.46 2.32e-19 Schizophrenia; LIHC cis rs3770081 1.000 rs59947468 chr2:86289436 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.96 -11.41 -0.53 9.09e-26 Facial emotion recognition (sad faces); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08857478 chr17:74722826 JMJD6;C17orf95 0.43 6.55 0.33 2.14e-10 Cognitive function; LIHC cis rs13394619 1.000 rs2358040 chr2:11731774 G/T cg07314298 chr2:11723111 GREB1 0.47 8.89 0.43 3.68e-17 Endometriosis; LIHC cis rs9814567 0.964 rs9820425 chr3:134223018 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.38 -0.56 2.41e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9614461 0.702 rs16993867 chr22:45733199 A/G cg13318129 chr22:45737514 FAM118A 0.47 7.43 0.37 8.82e-13 Tonsillectomy; LIHC cis rs6912958 0.712 rs6908386 chr6:88354746 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.91 -0.39 3.48e-14 Monocyte percentage of white cells; LIHC cis rs3820068 0.705 rs2042369 chr1:15843244 A/G cg17385448 chr1:15911702 AGMAT -0.41 -7.13 -0.36 5.88e-12 Systolic blood pressure; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs10463316 0.894 rs7723016 chr5:150764828 T/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.12e-10 Metabolite levels (Pyroglutamine); LIHC cis rs6912958 0.781 rs3918467 chr6:88180388 C/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.29 -0.37 2.12e-12 Monocyte percentage of white cells; LIHC cis rs6582630 0.555 rs10880607 chr12:38508184 A/G cg13010199 chr12:38710504 ALG10B 0.57 6.82 0.35 4.04e-11 Drug-induced liver injury (flucloxacillin); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg26545112 chr7:97833388 LMTK2 0.36 6.05 0.31 3.71e-9 Longevity; LIHC cis rs7250872 0.647 rs2304612 chr19:1817866 A/G cg18850929 chr19:1828978 REXO1 -0.4 -6.62 -0.34 1.4e-10 Bipolar disorder; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg12419862 chr22:24373484 LOC391322 -0.68 -10.42 -0.49 2.9e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs13191362 0.935 rs7767254 chr6:162954674 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.71 6.16 0.32 2.02e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs782590 0.902 rs7582278 chr2:55742924 C/G cg03859395 chr2:55845619 SMEK2 0.91 15.73 0.65 2.49e-42 Metabolic syndrome; LIHC cis rs8044868 0.530 rs7940 chr16:72146441 C/G cg16558253 chr16:72132732 DHX38 -0.4 -6.84 -0.35 3.75e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs9303401 0.659 rs17222621 chr17:56695923 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC trans rs11039798 0.557 rs4436575 chr11:48398894 T/C cg15704280 chr7:45808275 SEPT13 -0.57 -6.32 -0.32 8.05e-10 Axial length; LIHC cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.83 0.3 1.26e-8 Calcium levels; LIHC cis rs7726839 0.578 rs10080150 chr5:593160 C/T cg09021430 chr5:549028 NA 0.34 10.17 0.48 2.17e-21 Obesity-related traits; LIHC cis rs1707322 1.000 rs1588663 chr1:46548825 G/A cg03146154 chr1:46216737 IPP -0.45 -7.27 -0.37 2.52e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg00684032 chr4:1343700 KIAA1530 0.4 6.81 0.35 4.42e-11 Obesity-related traits; LIHC cis rs1538970 0.847 rs1771550 chr1:45883565 C/T cg24296786 chr1:45957014 TESK2 0.51 7.57 0.38 3.52e-13 Platelet count; LIHC cis rs9916302 0.904 rs12450559 chr17:37694709 G/A cg15445000 chr17:37608096 MED1 0.38 5.83 0.3 1.26e-8 Glomerular filtration rate (creatinine); LIHC cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg19318889 chr4:1322082 MAEA 0.43 5.9 0.3 8.7e-9 Obesity-related traits; LIHC cis rs2153535 0.504 rs4493781 chr6:8473941 G/C cg21535247 chr6:8435926 SLC35B3 0.61 8.03 0.4 1.59e-14 Motion sickness; LIHC cis rs1865760 0.892 rs9379806 chr6:25940958 G/A cg03517284 chr6:25882590 NA -0.44 -6.65 -0.34 1.17e-10 Height; LIHC cis rs3741404 0.560 rs17699798 chr11:63898806 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.7 -10.27 -0.49 9.92e-22 Platelet count; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg02963556 chr12:132588637 EP400NL 0.52 6.12 0.31 2.51e-9 Lung function (FEV1); LIHC cis rs7224685 0.569 rs7221595 chr17:4007594 C/T cg11204139 chr17:3907470 NA -0.53 -6.19 -0.32 1.73e-9 Type 2 diabetes; LIHC cis rs2153535 0.580 rs2143354 chr6:8517907 G/A cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.26e-27 Motion sickness; LIHC cis rs10752881 1.000 rs12753817 chr1:182970337 A/T ch.1.3577855R chr1:183094577 LAMC1 0.57 10.19 0.48 1.86e-21 Colorectal cancer; LIHC cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.13 -0.44 6.13e-18 Bipolar disorder; LIHC cis rs2153535 0.580 rs6597330 chr6:8492076 T/C cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs12549902 1.000 rs12549902 chr8:41509259 C/T cg17182837 chr8:41585554 ANK1 -0.23 -5.77 -0.3 1.77e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs2404602 0.647 rs11072612 chr15:76960984 A/T cg03037974 chr15:76606532 NA -0.61 -10.28 -0.49 8.54e-22 Blood metabolite levels; LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg20295408 chr7:1910781 MAD1L1 -0.49 -7.01 -0.35 1.26e-11 Bipolar disorder and schizophrenia; LIHC cis rs3736757 0.603 rs9425340 chr1:184650963 T/C cg07817967 chr1:184721222 EDEM3 0.36 5.78 0.3 1.65e-8 Obesity-related traits; LIHC cis rs6752107 0.503 rs2304776 chr2:234227693 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.43 6.23 0.32 1.33e-9 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7258465 1.000 rs8105994 chr19:18593553 A/G cg10790698 chr19:18539756 SSBP4 -0.33 -7.15 -0.36 5.36e-12 Breast cancer; LIHC cis rs5770917 1.000 rs1056964 chr22:51017476 A/G cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.51 -6.85 -0.35 3.42e-11 Narcolepsy; LIHC cis rs6424115 0.830 rs3123554 chr1:24196401 C/T cg10978503 chr1:24200527 CNR2 -0.35 -8.25 -0.41 3.57e-15 Immature fraction of reticulocytes; LIHC cis rs763121 0.853 rs4821810 chr22:39072098 C/G cg14440974 chr22:39074834 NA -0.36 -6.12 -0.31 2.63e-9 Menopause (age at onset); LIHC cis rs116248771 0.739 rs73156423 chr3:158345628 C/A cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.77e-10 diarrhoeal disease at age 2; LIHC cis rs12291225 0.585 rs11023197 chr11:14380998 G/A cg05501817 chr11:14380813 RRAS2 -0.45 -6.28 -0.32 1.01e-9 Sense of smell; LIHC cis rs546131 0.642 rs35833762 chr11:34845858 C/A cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.49 -0.33 3.05e-10 Lung disease severity in cystic fibrosis; LIHC cis rs6860806 0.531 rs272888 chr5:131665423 T/C cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.79e-31 Breast cancer; LIHC cis rs1005277 0.579 rs2021649 chr10:38392122 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs6121246 0.567 rs6058187 chr20:30190923 T/C cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs11583043 0.918 rs11582211 chr1:101416871 G/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.02 0.31 4.41e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs752010 0.806 rs11210500 chr1:42089737 A/G cg06885757 chr1:42089581 HIVEP3 0.32 6.71 0.34 8.06e-11 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs4268898 0.636 rs76172309 chr2:24458911 G/C cg06627628 chr2:24431161 ITSN2 -0.73 -9.76 -0.47 5.02e-20 Asthma; LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg10774155 chr7:65338427 VKORC1L1 0.45 6.56 0.33 2.02e-10 Calcium levels; LIHC cis rs8103278 1.000 rs17571725 chr19:46290822 C/T cg14061069 chr19:46274453 DMPK -0.55 -8.6 -0.42 2.92e-16 Coronary artery disease; LIHC cis rs7927592 0.913 rs3740631 chr11:68341722 T/G cg16797656 chr11:68205561 LRP5 0.5 7.8 0.39 7.44e-14 Total body bone mineral density; LIHC cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.45 8.48 0.42 7.04e-16 Total body bone mineral density; LIHC cis rs651907 0.557 rs11710533 chr3:101351472 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.66 0.53 1.12e-26 Colorectal cancer; LIHC cis rs9902453 0.933 rs60694493 chr17:28473256 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.87 0.43 4.04e-17 Coffee consumption (cups per day); LIHC cis rs694739 0.595 rs11542299 chr11:64138805 T/C cg23796481 chr11:64053134 BAD;GPR137 0.47 6.23 0.32 1.34e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs12908161 1.000 rs62021219 chr15:85256159 C/T cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC cis rs17433710 0.543 rs4657222 chr1:162644317 C/G cg01063088 chr1:162760584 HSD17B7 -0.4 -5.75 -0.3 2.01e-8 Dupuytren's disease; LIHC cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg12516959 chr21:47718080 NA 0.44 6.85 0.35 3.4e-11 Testicular germ cell tumor; LIHC cis rs9503598 0.644 rs7774747 chr6:3430996 A/G cg00476032 chr6:3446245 SLC22A23 -0.32 -6.1 -0.31 2.79e-9 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC trans rs800082 0.839 rs62275528 chr3:144293687 T/C cg24215973 chr2:240111563 HDAC4 -0.49 -6.83 -0.35 3.97e-11 Smoking behavior; LIHC cis rs12477438 1.000 rs73963398 chr2:99887025 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.73 -8.57 -0.42 3.54e-16 Chronic sinus infection; LIHC cis rs72949976 1.000 rs72949976 chr2:214034104 C/T cg08319019 chr2:214017104 IKZF2 -0.63 -6.8 -0.35 4.67e-11 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg11644478 chr21:40555479 PSMG1 0.83 10.51 0.49 1.38e-22 Cognitive function; LIHC cis rs9814567 1.000 rs4367113 chr3:134287975 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2153535 0.580 rs718502 chr6:8527400 T/C cg23788917 chr6:8435910 SLC35B3 0.64 9.09 0.44 7.98e-18 Motion sickness; LIHC cis rs700651 0.786 rs58224025 chr2:198821988 G/A cg03934865 chr2:198174659 NA 0.47 6.84 0.35 3.75e-11 Intracranial aneurysm; LIHC cis rs11758351 0.789 rs2069020 chr6:26205500 C/T cg02902477 chr6:26197071 HIST1H3D 0.53 5.73 0.3 2.15e-8 Gout;Renal underexcretion gout; LIHC cis rs4319547 0.619 rs10744208 chr12:122931559 C/A cg23029597 chr12:123009494 RSRC2 -0.53 -7.4 -0.37 1.04e-12 Body mass index; LIHC cis rs651907 0.535 rs2290859 chr3:101525625 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.62 9.76 0.47 5.27e-20 Colorectal cancer; LIHC cis rs7224314 1.000 rs62084078 chr17:65386886 T/C cg01507342 chr17:65387096 PITPNC1 -0.49 -6.14 -0.32 2.23e-9 Diisocyanate-induced asthma; LIHC cis rs7662987 0.517 rs2602866 chr4:100034997 A/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs12477438 0.765 rs56167745 chr2:99600478 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.48 -0.37 6.34e-13 Chronic sinus infection; LIHC cis rs62084913 0.511 rs895690 chr17:72784649 C/T cg25054828 chr17:72772726 NAT9;TMEM104 0.58 9.18 0.44 4.3e-18 Breast cancer; LIHC cis rs908922 0.582 rs1856121 chr1:152512169 A/T cg20991723 chr1:152506922 NA 0.51 8.75 0.43 1.01e-16 Hair morphology; LIHC cis rs9628987 0.569 rs11121174 chr1:8431105 C/G cg20416874 chr1:8611966 RERE 0.49 5.99 0.31 5.3300000000000004e-09 Breast cancer; LIHC cis rs34779708 0.702 rs4244995 chr10:35547175 A/G cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC trans rs4843747 0.636 rs11117358 chr16:88105053 T/A cg09572067 chr16:29127029 RRN3P2 0.51 8.11 0.4 9.47e-15 Menopause (age at onset); LIHC cis rs249954 0.512 rs249870 chr16:23666178 C/A cg01460202 chr16:23706506 ERN2 0.36 5.97 0.31 5.9e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4788570 0.615 rs2334880 chr16:71653637 A/G cg06353428 chr16:71660113 MARVELD3 1.33 14.1 0.61 6.87e-36 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.600 rs2895202 chr7:2131829 T/C cg02951883 chr7:2050386 MAD1L1 -0.66 -10.69 -0.5 3.41e-23 Bipolar disorder and schizophrenia; LIHC cis rs1728785 1.000 rs864741 chr16:68576577 C/T cg02972257 chr16:68554789 NA -0.53 -6.1 -0.31 2.95e-9 Ulcerative colitis; LIHC cis rs801193 0.569 rs2707847 chr7:66202871 C/G cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.34e-11 Aortic root size; LIHC cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.97 9.12 0.44 6.71e-18 Platelet count; LIHC cis rs743757 0.878 rs12494849 chr3:50524558 C/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.46 7.1 0.36 7.09e-12 Diastolic blood pressure; LIHC trans rs1005277 0.540 rs1814077 chr10:37992018 G/C cg23533926 chr12:111358616 MYL2 -0.33 -6.46 -0.33 3.56e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7100689 0.646 rs1538823 chr10:82088040 C/A cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs7635838 0.684 rs346079 chr3:11328139 G/A cg00170343 chr3:11313890 ATG7 0.58 9.85 0.47 2.55e-20 HDL cholesterol; LIHC cis rs8180040 0.966 rs7651762 chr3:47470484 G/A cg16586182 chr3:47516702 SCAP 0.61 12.12 0.55 2.35e-28 Colorectal cancer; LIHC cis rs743757 0.878 rs9867588 chr3:50526880 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.47 7.0 0.35 1.38e-11 Diastolic blood pressure; LIHC cis rs4906332 1.000 rs35862113 chr14:103857229 G/T cg04998671 chr14:104000505 TRMT61A -0.43 -5.8 -0.3 1.55e-8 Coronary artery disease; LIHC cis rs921968 0.643 rs590771 chr2:219369851 C/T cg18887096 chr2:219472410 PLCD4 0.36 6.46 0.33 3.52e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1707322 1.000 rs9429186 chr1:46539687 C/T cg03146154 chr1:46216737 IPP -0.44 -7.05 -0.36 9.75e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3096299 0.503 rs9925045 chr16:89556476 T/C cg06640241 chr16:89574553 SPG7 0.81 14.87 0.63 6.34e-39 Multiple myeloma (IgH translocation); LIHC cis rs6722750 0.905 rs10170666 chr2:64379672 G/A cg22352474 chr2:64371530 PELI1 0.54 7.59 0.38 3.13e-13 Neuroticism; LIHC cis rs6963495 0.818 rs73190158 chr7:105153943 T/C cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs780096 0.546 rs2293572 chr2:27728777 C/G cg05484376 chr2:27715224 FNDC4 -0.38 -6.41 -0.33 4.71e-10 Total body bone mineral density; LIHC cis rs6690583 0.623 rs61768852 chr1:85454613 T/C cg22153463 chr1:85462885 MCOLN2 0.5 6.03 0.31 4.19e-9 Serum sulfate level; LIHC cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs2245008 0.671 rs907036 chr16:83989850 A/T cg27171569 chr16:83987465 OSGIN1 0.39 7.72 0.39 1.25e-13 Pursuit maintenance gain; LIHC cis rs72781680 1.000 rs72781649 chr2:24210864 A/G cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs992157 0.835 rs13031757 chr2:219151926 T/C cg00012203 chr2:219082015 ARPC2 -0.83 -13.21 -0.58 1.76e-32 Colorectal cancer; LIHC cis rs7618501 0.633 rs9861216 chr3:50059339 A/G cg24110177 chr3:50126178 RBM5 0.45 7.35 0.37 1.45e-12 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.645 rs10742953 chr11:49807491 C/G cg18944383 chr4:111397179 ENPEP -0.28 -7.17 -0.36 4.55e-12 Height; LIHC cis rs10170846 0.530 rs56353541 chr2:223421187 G/C cg25565276 chr2:223520875 FARSB 0.72 10.24 0.48 1.23e-21 Schizophrenia (inflammation and infection response interaction); LIHC cis rs8114671 0.527 rs2253484 chr20:33405263 A/T cg07148914 chr20:33460835 GGT7 -0.6 -8.97 -0.44 1.95e-17 Height; LIHC cis rs11122272 0.701 rs2474628 chr1:231526000 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs950169 0.881 rs4842852 chr15:84941961 A/G cg03959625 chr15:84868606 LOC388152 0.47 6.68 0.34 9.94e-11 Schizophrenia; LIHC cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg27572855 chr1:25598939 RHD 0.4 8.79 0.43 7.25e-17 Erythrocyte sedimentation rate; LIHC cis rs3020736 0.500 rs4147641 chr22:42482502 C/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs6723226 0.750 rs3769597 chr2:32691400 T/G cg02381751 chr2:32503542 YIPF4 0.63 9.56 0.46 2.45e-19 Intelligence (multi-trait analysis); LIHC cis rs875971 0.895 rs4718349 chr7:65909011 C/G cg18876405 chr7:65276391 NA 0.38 6.86 0.35 3.22e-11 Aortic root size; LIHC cis rs9914988 0.943 rs4262997 chr17:27129562 A/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs9303401 0.659 rs34426768 chr17:56683385 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.98 12.97 0.57 1.48e-31 Cognitive test performance; LIHC cis rs5997397 0.934 rs6005864 chr22:29157487 A/G cg15103426 chr22:29168792 CCDC117 -0.56 -8.8 -0.43 6.74e-17 Red cell distribution width; LIHC cis rs919433 0.617 rs4850436 chr2:198541398 C/T cg00792783 chr2:198669748 PLCL1 -0.42 -6.02 -0.31 4.44e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3768617 0.510 rs6424888 chr1:183085696 C/T ch.1.3577855R chr1:183094577 LAMC1 -0.57 -10.34 -0.49 5.44e-22 Fuchs's corneal dystrophy; LIHC cis rs780096 0.587 rs4665969 chr2:27574953 C/T cg22903471 chr2:27725779 GCKR 0.46 8.27 0.41 2.96e-15 Total body bone mineral density; LIHC cis rs11969893 0.850 rs9485417 chr6:101300038 C/T cg12253828 chr6:101329408 ASCC3 -1.07 -14.42 -0.61 3.67e-37 Economic and political preferences (immigration/crime); LIHC cis rs2806561 0.765 rs1738469 chr1:23511407 G/C cg12483005 chr1:23474871 LUZP1 0.45 7.14 0.36 5.7e-12 Height; LIHC cis rs10489202 1.000 rs2272911 chr1:167936302 C/T cg24449463 chr1:168025552 DCAF6 -0.53 -6.73 -0.34 7.36e-11 Schizophrenia; LIHC cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg27286337 chr10:134555280 INPP5A 0.9 14.23 0.61 2.08e-36 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs644799 0.965 rs10831425 chr11:95500628 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.63 0.46 1.45e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10508774 1.000 rs117289882 chr10:32837927 T/C cg01819863 chr10:32635814 EPC1 0.65 5.97 0.31 5.96e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs1814175 0.817 rs10839351 chr11:49758153 C/T cg03929089 chr4:120376271 NA -0.9 -18.34 -0.7 8.56e-53 Height; LIHC cis rs2370759 1.000 rs11599044 chr10:32615445 A/G cg01819863 chr10:32635814 EPC1 1.08 16.15 0.66 5.45e-44 Sexual dysfunction (female); LIHC cis rs600806 0.850 rs1465607 chr1:109958035 T/C cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.17 -0.36 4.54e-12 Intelligence (multi-trait analysis); LIHC cis rs11971779 0.680 rs11768023 chr7:139054395 T/A cg07862535 chr7:139043722 LUC7L2 0.61 10.58 0.5 7.87e-23 Diisocyanate-induced asthma; LIHC cis rs2842992 0.830 rs2758313 chr6:160154099 C/G cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.89 0.43 3.64e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs11675119 0.501 rs9751941 chr2:3494262 C/T cg15541040 chr2:3486749 NA -0.39 -5.72 -0.3 2.37e-8 Neurofibrillary tangles; LIHC cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.95 -0.51 3.91e-24 Platelet count; LIHC cis rs17685 0.753 rs6465000 chr7:75787417 G/A cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs877282 0.583 rs11253424 chr10:813426 C/T cg22713356 chr15:30763199 NA 0.83 7.67 0.38 1.78e-13 Uric acid levels; LIHC cis rs2075371 0.830 rs12669960 chr7:133931782 A/G cg11752832 chr7:134001865 SLC35B4 0.45 5.73 0.3 2.22e-8 Mean platelet volume; LIHC cis rs2115630 0.967 rs8028490 chr15:85277888 G/A cg12501888 chr15:85177176 SCAND2 -0.52 -8.1 -0.4 9.48e-15 P wave terminal force; LIHC trans rs5756813 0.661 rs5995500 chr22:38204640 A/G cg19894588 chr14:64061835 NA -0.68 -10.13 -0.48 2.97e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7312933 0.703 rs11181378 chr12:42600658 T/C cg17420585 chr12:42539391 GXYLT1 -0.37 -5.89 -0.3 9.18e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7919006 0.590 rs72642258 chr10:76803416 A/G cg01390419 chr10:76803856 DUPD1 0.5 7.82 0.39 6.68e-14 Weight; LIHC trans rs11098499 0.909 rs28884220 chr4:120307211 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.64 0.42 2.14e-16 Corneal astigmatism; LIHC cis rs826838 0.967 rs1352123 chr12:39130992 T/C cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs9790314 1.000 rs7638668 chr3:161047283 G/A cg03342759 chr3:160939853 NMD3 -0.69 -8.39 -0.41 1.25e-15 Morning vs. evening chronotype; LIHC cis rs6502050 0.835 rs7406529 chr17:80080877 C/T cg11859384 chr17:80120422 CCDC57 0.43 5.95 0.31 6.76e-9 Life satisfaction; LIHC cis rs6001982 0.510 rs55844816 chr22:40803112 C/T cg07138101 chr22:40742427 ADSL 0.59 6.36 0.33 6.56e-10 Breast cancer; LIHC cis rs311392 0.554 rs376765 chr8:55097188 A/G cg11783602 chr8:55087084 NA -0.31 -6.19 -0.32 1.73e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs2404602 0.647 rs4312276 chr15:77164361 T/C cg23625390 chr15:77176239 SCAPER -0.55 -9.15 -0.44 5.45e-18 Blood metabolite levels; LIHC cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg19318889 chr4:1322082 MAEA 0.62 9.79 0.47 4.12e-20 Longevity; LIHC cis rs6120849 0.707 rs6088694 chr20:33652371 G/A cg24642439 chr20:33292090 TP53INP2 0.65 7.03 0.36 1.11e-11 Protein C levels; LIHC cis rs1577917 0.958 rs13201730 chr6:86556647 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.46 -0.37 7.34e-13 Response to antipsychotic treatment; LIHC cis rs9814567 1.000 rs1863913 chr3:134200205 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.28 -0.55 5.59e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11018874 0.597 rs10765243 chr11:89855118 C/G cg23743573 chr11:89867420 NAALAD2 0.39 5.85 0.3 1.15e-8 White blood cell types; LIHC cis rs4631830 0.720 rs12763717 chr10:51500874 C/G cg20129853 chr10:51489980 NA 0.39 8.49 0.42 6.42e-16 Prostate-specific antigen levels; LIHC cis rs6951245 0.554 rs79367977 chr7:1152657 G/A cg04025307 chr7:1156635 C7orf50 0.62 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12497850 0.864 rs4513485 chr3:49139966 G/A cg06212747 chr3:49208901 KLHDC8B 0.6 7.93 0.39 3.05e-14 Parkinson's disease; LIHC cis rs6665290 0.904 rs2297416 chr1:227172935 C/G cg10327440 chr1:227177885 CDC42BPA -1.18 -25.61 -0.81 1.64e-81 Myeloid white cell count; LIHC cis rs1023500 0.505 rs134889 chr22:42674350 A/T cg00645731 chr22:42541494 CYP2D7P1 0.34 6.01 0.31 4.66e-9 Schizophrenia; LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs9814567 0.806 rs4519744 chr3:134321523 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs72627123 0.867 rs3815331 chr14:74482948 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 9.12 0.44 6.58e-18 Morning vs. evening chronotype; LIHC cis rs9543976 0.920 rs9543992 chr13:76175074 G/A cg01531495 chr13:76123901 UCHL3 0.49 5.84 0.3 1.23e-8 Diabetic retinopathy; LIHC cis rs778371 0.676 rs13024330 chr2:233715487 A/G cg08000102 chr2:233561755 GIGYF2 0.75 9.26 0.45 2.28e-18 Schizophrenia; LIHC cis rs1789 0.868 rs4631041 chr4:15673395 A/T cg21329975 chr4:15471214 CC2D2A -0.4 -5.99 -0.31 5.2e-9 Blood protein levels; LIHC cis rs4974559 1.000 rs4974559 chr4:1380848 C/T cg16405210 chr4:1374714 KIAA1530 0.45 6.1 0.31 2.8e-9 Systolic blood pressure; LIHC cis rs875971 0.558 rs4433015 chr7:65639723 A/C cg18876405 chr7:65276391 NA -0.49 -8.06 -0.4 1.33e-14 Aortic root size; LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs3736594 0.759 rs6753736 chr2:27958855 C/G cg27432699 chr2:27873401 GPN1 -0.45 -6.85 -0.35 3.38e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6952808 0.792 rs11771973 chr7:1950440 C/G cg14004847 chr7:1930337 MAD1L1 -0.48 -6.74 -0.34 6.84e-11 Bipolar disorder and schizophrenia; LIHC cis rs7208859 0.623 rs34756112 chr17:29113016 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1185460 0.547 rs34150933 chr11:118911039 C/T cg23280166 chr11:118938394 VPS11 -0.45 -6.18 -0.32 1.86e-9 Coronary artery disease; LIHC cis rs80282103 0.867 rs17155821 chr10:1071701 A/G cg20335179 chr10:1068567 C10orf110;IDI2 -0.61 -6.73 -0.34 7.32e-11 Glomerular filtration rate (creatinine); LIHC cis rs7602441 0.521 rs6704919 chr2:14768496 G/A cg06545361 chr2:14773388 FAM84A 0.49 5.72 0.3 2.32e-8 Visceral adipose tissue adjusted for BMI; LIHC cis rs7777484 0.500 rs2533885 chr7:2835655 C/T cg13628971 chr7:2884303 GNA12 0.34 5.74 0.3 2.12e-8 Height; LIHC cis rs736408 0.608 rs2239547 chr3:52855229 T/C cg11645453 chr3:52864694 ITIH4 0.29 7.64 0.38 2.28e-13 Bipolar disorder; LIHC cis rs751728 0.965 rs2013381 chr6:33763837 C/T cg25922239 chr6:33757077 LEMD2 0.44 7.33 0.37 1.66e-12 Crohn's disease; LIHC cis rs9660992 0.573 rs7531256 chr1:205191202 T/G cg21545522 chr1:205238299 TMCC2 0.37 7.15 0.36 5.22e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs9733 0.596 rs34600506 chr1:150687808 C/G cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs986417 1.000 rs2093212 chr14:60843322 G/A cg27398547 chr14:60952738 C14orf39 -0.79 -9.02 -0.44 1.36e-17 Gut microbiota (bacterial taxa); LIHC cis rs910316 0.763 rs4556 chr14:75476071 G/C cg08847533 chr14:75593920 NEK9 0.88 18.04 0.7 1.32e-51 Height; LIHC cis rs7615952 0.611 rs9681518 chr3:125615130 A/G cg05084668 chr3:125655381 ALG1L -0.82 -10.76 -0.5 1.89e-23 Blood pressure (smoking interaction); LIHC cis rs4555082 0.874 rs2816620 chr14:105732704 G/T cg13114125 chr14:105738426 BRF1 -0.79 -10.09 -0.48 4e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.65 9.51 0.46 3.43e-19 Lymphocyte counts; LIHC cis rs34779708 0.966 rs12769484 chr10:35465746 G/A cg04310649 chr10:35416472 CREM -0.42 -5.74 -0.3 2.06e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs1920116 0.778 rs2421830 chr3:169554129 G/A cg00669760 chr2:44735195 C2orf34 0.38 6.12 0.31 2.51e-9 Glioma (high-grade); LIHC cis rs11792861 0.591 rs4978763 chr9:111728067 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.68 11.32 0.52 1.95e-25 Menarche (age at onset); LIHC cis rs7100689 0.555 rs1934146 chr10:82062121 C/A cg00277334 chr10:82204260 NA -0.6 -7.53 -0.38 4.49e-13 Post bronchodilator FEV1; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg12016809 chr21:47604291 C21orf56 -0.47 -7.32 -0.37 1.75e-12 Testicular germ cell tumor; LIHC cis rs9303401 0.921 rs34102441 chr17:56877414 A/G cg05425664 chr17:57184151 TRIM37 -0.52 -7.36 -0.37 1.4e-12 Cognitive test performance; LIHC cis rs11676348 0.846 rs3890158 chr2:218990292 G/A cg00012203 chr2:219082015 ARPC2 -0.55 -7.78 -0.39 8.65e-14 Ulcerative colitis; LIHC cis rs7107174 0.892 rs10431155 chr11:78121978 T/C cg02023728 chr11:77925099 USP35 0.41 7.48 0.37 6.44e-13 Testicular germ cell tumor; LIHC cis rs6089584 0.861 rs2180302 chr20:60576369 A/G cg13770153 chr20:60521292 NA -0.32 -6.26 -0.32 1.19e-9 Body mass index; LIHC cis rs17376456 0.825 rs10038828 chr5:93124056 C/T cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs4920343 0.671 rs1010113 chr1:19071752 T/C cg19637330 chr1:19110922 NA 0.31 5.82 0.3 1.38e-8 Knee osteoarthritis; LIHC cis rs9790314 1.000 rs28515190 chr3:161028605 G/A cg04691961 chr3:161091175 C3orf57 -0.42 -6.57 -0.33 1.93e-10 Morning vs. evening chronotype; LIHC trans rs916888 0.773 rs169201 chr17:44790203 A/G cg16836995 chr17:43662488 NA -0.75 -7.69 -0.38 1.55e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs17152411 0.895 rs7094116 chr10:126587644 T/G cg07906193 chr10:126599966 NA 0.42 6.64 0.34 1.22e-10 Height; LIHC trans rs1581253 1.000 rs1581253 chr2:180335135 A/G cg23035555 chr19:3500370 DOHH -0.48 -6.28 -0.32 1.05e-9 Gestational age at birth in labor-initiated deliveries (child effect); LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs6089584 0.821 rs4925332 chr20:60604639 C/T cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.65e-10 Body mass index; LIHC cis rs4409675 0.576 rs2474470 chr1:28234999 C/T cg23691781 chr1:28212827 C1orf38 0.32 7.58 0.38 3.28e-13 Corneal astigmatism; LIHC cis rs25645 0.502 rs9895948 chr17:38108363 T/C cg17467752 chr17:38218738 THRA 0.4 6.05 0.31 3.79e-9 Myeloid white cell count; LIHC cis rs16828019 0.852 rs34979067 chr1:41543084 G/A cg03387723 chr1:41708464 SCMH1 -0.4 -6.53 -0.33 2.36e-10 Intelligence (multi-trait analysis); LIHC cis rs3796352 0.881 rs11710394 chr3:53015839 A/G cg07884673 chr3:53033167 SFMBT1 0.91 6.6 0.34 1.58e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.06e-19 Renal cell carcinoma; LIHC cis rs9811920 0.609 rs4244711 chr3:99657205 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.8 -0.3 1.48e-8 Axial length; LIHC cis rs6456156 0.792 rs10946215 chr6:167516181 A/G cg07741184 chr6:167504864 NA -0.26 -6.09 -0.31 3.09e-9 Primary biliary cholangitis; LIHC cis rs796364 0.806 rs34510964 chr2:201010676 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.66 -7.71 -0.38 1.41e-13 Schizophrenia; LIHC cis rs8072100 0.934 rs9905583 chr17:45741016 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.39 -6.15 -0.32 2.19e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7937890 0.904 rs7484197 chr11:14283654 C/T cg22961513 chr11:14280813 SPON1 -0.5 -7.69 -0.38 1.62e-13 Mitochondrial DNA levels; LIHC cis rs11792861 0.926 rs7856626 chr9:111775502 C/G cg13535736 chr9:111863775 C9orf5 -0.4 -6.11 -0.31 2.67e-9 Menarche (age at onset); LIHC cis rs965469 0.724 rs2007022 chr20:3237674 C/A cg25506879 chr20:3388711 C20orf194 -0.51 -6.24 -0.32 1.3e-9 IFN-related cytopenia; LIHC cis rs7119038 0.818 rs17122453 chr11:118683564 G/A cg19308663 chr11:118741387 NA 0.39 6.03 0.31 4.2e-9 Sjögren's syndrome; LIHC cis rs7100689 0.646 rs7894762 chr10:82086779 C/G cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg11070056 chr1:107600091 PRMT6 0.7 12.12 0.55 2.31e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11059919 1 rs11059919 chr12:129289190 G/A cg09035930 chr12:129282057 SLC15A4 0.68 12.95 0.57 1.69e-31 Systemic lupus erythematosus; LIHC cis rs6782228 0.651 rs9289332 chr3:128387884 C/G cg16766828 chr3:128327626 NA -0.43 -6.77 -0.34 5.68e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs3736485 0.966 rs10467923 chr15:51767265 A/C cg08986416 chr15:51914746 DMXL2 -0.4 -5.75 -0.3 2.01e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2072499 0.750 rs2241109 chr1:156173082 C/T cg24450063 chr1:156163899 SLC25A44 0.77 8.38 0.41 1.38e-15 Testicular germ cell tumor; LIHC cis rs11122272 0.735 rs2247132 chr1:231493359 G/A cg06096015 chr1:231504339 EGLN1 0.5 9.13 0.44 6.02e-18 Hemoglobin concentration; LIHC cis rs9911578 1.000 rs7215808 chr17:56940742 G/C cg12560992 chr17:57184187 TRIM37 0.98 17.39 0.69 5.65e-49 Intelligence (multi-trait analysis); LIHC trans rs637571 0.565 rs633800 chr11:65638719 G/A cg17712092 chr4:129076599 LARP1B -0.69 -9.89 -0.47 1.83e-20 Eosinophil percentage of white cells; LIHC cis rs35110281 0.840 rs7276633 chr21:45078800 C/T cg04455712 chr21:45112962 RRP1B 0.46 7.88 0.39 4.32e-14 Mean corpuscular volume; LIHC cis rs17685 0.753 rs6464999 chr7:75787315 T/C cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7674212 0.541 rs2720460 chr4:104054686 C/T cg16532752 chr4:104119610 CENPE 0.44 6.92 0.35 2.18e-11 Type 2 diabetes; LIHC cis rs35110281 0.627 rs7283362 chr21:44973667 C/G cg01579765 chr21:45077557 HSF2BP -0.31 -5.86 -0.3 1.09e-8 Mean corpuscular volume; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.15 0.55 1.81e-28 Prudent dietary pattern; LIHC cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg00343986 chr7:65444356 GUSB 0.44 6.22 0.32 1.43e-9 Calcium levels; LIHC cis rs798554 0.797 rs798486 chr7:2803037 A/G cg13628971 chr7:2884303 GNA12 0.52 7.68 0.38 1.69e-13 Height; LIHC cis rs1023500 0.505 rs134887 chr22:42674239 A/G cg15557168 chr22:42548783 NA -0.34 -5.81 -0.3 1.43e-8 Schizophrenia; LIHC cis rs4700695 0.841 rs706680 chr5:65317338 T/C cg21114390 chr5:65439923 SFRS12 0.45 5.87 0.3 1.05e-8 Facial morphology (factor 19); LIHC trans rs3743102 0.591 rs78104714 chr15:83381199 C/G cg01542190 chr22:50604728 NA -0.55 -7.39 -0.37 1.14e-12 Colorectal adenoma (advanced); LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.45 7.48 0.37 6.49e-13 Height; LIHC cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg15691649 chr6:25882328 NA -0.55 -7.11 -0.36 6.75e-12 Intelligence (multi-trait analysis); LIHC cis rs2795502 0.873 rs3121282 chr10:43423626 T/A cg20628663 chr10:43360327 NA 0.44 6.46 0.33 3.53e-10 Blood protein levels; LIHC cis rs60871478 0.898 rs4720929 chr7:808009 T/C cg13844804 chr7:814759 HEATR2 0.44 5.88 0.3 9.97e-9 Cerebrospinal P-tau181p levels; LIHC cis rs1451375 0.527 rs6950777 chr7:50597056 G/A cg14593290 chr7:50529359 DDC 0.55 8.74 0.43 1.05e-16 Malaria; LIHC cis rs2742417 0.603 rs2742374 chr3:45784082 T/C cg04837898 chr3:45731254 SACM1L -0.51 -8.61 -0.42 2.64e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs10751667 0.961 rs7480178 chr11:927108 T/C ch.11.42038R chr11:967971 AP2A2 0.57 10.48 0.49 1.74e-22 Alzheimer's disease (late onset); LIHC cis rs7940866 0.834 rs2324315 chr11:130839772 C/G cg12179176 chr11:130786555 SNX19 0.63 9.18 0.44 4.19e-18 Schizophrenia; LIHC cis rs3768617 0.510 rs1413388 chr1:183096694 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs7659604 0.540 rs9995322 chr4:122675642 G/A cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.7e-11 Type 2 diabetes; LIHC trans rs11098499 0.909 rs28571712 chr4:120375980 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.81 0.47 3.5e-20 Corneal astigmatism; LIHC cis rs6952808 0.693 rs10950413 chr7:1912988 A/G cg14004847 chr7:1930337 MAD1L1 -0.52 -7.47 -0.37 6.71e-13 Bipolar disorder and schizophrenia; LIHC cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg08499158 chr17:42289980 UBTF 0.5 8.11 0.4 9.22e-15 Total body bone mineral density; LIHC cis rs35110281 0.715 rs969060 chr21:45080852 T/G cg04455712 chr21:45112962 RRP1B 0.48 7.96 0.4 2.56e-14 Mean corpuscular volume; LIHC cis rs2228479 0.850 rs11649510 chr16:89851004 A/G cg06558623 chr16:89946397 TCF25 0.84 11.03 0.51 2.02e-24 Skin colour saturation; LIHC cis rs1865721 0.761 rs36002108 chr18:73220472 C/T cg26385618 chr18:73139727 C18orf62 -0.27 -6.83 -0.35 3.94e-11 Intelligence; LIHC cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg11764359 chr7:65958608 NA -0.68 -9.36 -0.45 1.11e-18 Aortic root size; LIHC cis rs7618501 0.521 rs3796386 chr3:49899795 G/A cg21467203 chr3:49911342 NA -0.62 -11.31 -0.52 2.03e-25 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.863 rs3775844 chr4:120428033 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.46 0.46 5.19e-19 Corneal astigmatism; LIHC cis rs17152411 1.000 rs7086447 chr10:126593553 C/A cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs7131987 0.868 rs7958210 chr12:29395181 G/C cg16970926 chr12:29381810 FAR2 0.35 7.5 0.38 5.52e-13 QT interval; LIHC cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg23758822 chr17:41437982 NA 0.94 17.49 0.69 2.15e-49 Menopause (age at onset); LIHC cis rs6089829 0.962 rs7273930 chr20:61666017 G/A cg08564027 chr20:61660810 NA 0.39 7.57 0.38 3.45e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs651907 0.557 rs36002990 chr3:101437862 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.4 0.49 3.31e-22 Colorectal cancer; LIHC cis rs3924048 0.559 rs4075303 chr1:12626593 C/G cg00291366 chr1:12616550 NA 0.38 7.82 0.39 6.44e-14 Optic cup area; LIHC cis rs10876993 0.890 rs1689584 chr12:58081478 G/A cg15848620 chr12:58087721 OS9 -0.59 -8.2 -0.41 4.96e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg12516959 chr21:47718080 NA 0.36 5.85 0.3 1.17e-8 Testicular germ cell tumor; LIHC cis rs2576037 0.583 rs9947131 chr18:44534769 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.73 11.54 0.53 3.02e-26 Personality dimensions; LIHC cis rs10949834 0.504 rs77541100 chr7:73555605 C/T cg07137043 chr7:73588983 EIF4H -0.73 -7.82 -0.39 6.58e-14 Verbal memory performance (residualized delayed recall change); LIHC cis rs727505 1.000 rs7791430 chr7:124429953 G/T cg23710748 chr7:124431027 NA -0.36 -6.35 -0.32 6.66e-10 Lewy body disease; LIHC trans rs877282 0.583 rs11253429 chr10:823234 A/C cg22713356 chr15:30763199 NA 0.79 6.78 0.34 5.39e-11 Uric acid levels; LIHC cis rs561341 0.843 rs879945 chr17:30242796 G/A cg12193833 chr17:30244370 NA -0.51 -5.94 -0.31 6.92e-9 Hip circumference adjusted for BMI; LIHC cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.83 0.3 1.29e-8 Menopause (age at onset); LIHC cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg02931644 chr1:25747376 RHCE 0.36 7.98 0.4 2.21e-14 Erythrocyte sedimentation rate; LIHC cis rs7131987 0.903 rs7308125 chr12:29425211 T/C cg12903224 chr12:29470962 FAR2 -0.41 -6.54 -0.33 2.3e-10 QT interval; LIHC cis rs644799 1.000 rs611020 chr11:95567905 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.6 0.67 8e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg25072359 chr17:41440525 NA 0.39 6.16 0.32 2e-9 Menopause (age at onset); LIHC cis rs6430585 0.528 rs78274583 chr2:136734569 C/T cg25344623 chr2:136566232 LCT -0.37 -5.93 -0.31 7.26e-9 Corneal structure; LIHC cis rs7412746 0.658 rs2230061 chr1:150727539 G/A cg18016565 chr1:150552671 MCL1 0.56 10.71 0.5 2.81e-23 Melanoma; LIHC cis rs1348850 0.567 rs3770011 chr2:178537890 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.82 0.39 6.84e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1712517 0.740 rs4917387 chr10:105108455 T/C cg05636881 chr10:105038444 INA 0.49 7.58 0.38 3.25e-13 Migraine; LIHC cis rs4759375 1.000 rs28532037 chr12:123883406 G/A cg00376283 chr12:123451042 ABCB9 0.5 6.13 0.31 2.45e-9 HDL cholesterol; LIHC cis rs950776 0.518 rs11636131 chr15:78821606 C/T cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs713477 1.000 rs8010013 chr14:55884828 A/C cg13175173 chr14:55914753 NA -0.31 -7.1 -0.36 7.2e-12 Pediatric bone mineral content (femoral neck); LIHC cis rs4803468 1.000 rs284663 chr19:41932612 C/T cg09537434 chr19:41945824 ATP5SL -1.03 -21.51 -0.76 1.55e-65 Height; LIHC cis rs7572733 0.536 rs6732517 chr2:198912902 G/C cg10820045 chr2:198174542 NA 0.41 6.11 0.31 2.68e-9 Dermatomyositis; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.09 -0.4 1.07e-14 Lymphocyte counts; LIHC cis rs7614311 0.681 rs73130565 chr3:63887135 T/C cg22134162 chr3:63841271 THOC7 -0.53 -5.99 -0.31 5.26e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs9399135 0.967 rs7773126 chr6:135318390 A/G cg22676075 chr6:135203613 NA 0.37 6.14 0.32 2.3e-9 Red blood cell count; LIHC cis rs72781680 1.000 rs72796389 chr2:24171761 A/G cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg08822215 chr16:89438651 ANKRD11 0.38 6.1 0.31 2.83e-9 Multiple myeloma (IgH translocation); LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs9858542 0.903 rs11921590 chr3:49644193 T/C cg03060546 chr3:49711283 APEH -0.59 -7.64 -0.38 2.21e-13 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2439831 1.000 rs550239 chr15:43720197 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.66 0.59 3.34e-34 Lung cancer in ever smokers; LIHC cis rs6964587 1.000 rs756647 chr7:91586389 A/G cg17063962 chr7:91808500 NA 1.01 19.29 0.72 1.3e-56 Breast cancer; LIHC cis rs5758511 0.680 rs5758684 chr22:42649509 C/T cg00645731 chr22:42541494 CYP2D7P1 0.53 8.58 0.42 3.35e-16 Birth weight; LIHC trans rs2727020 0.575 rs10769587 chr11:49549849 C/G cg18944383 chr4:111397179 ENPEP 0.25 6.16 0.32 1.99e-9 Coronary artery disease; LIHC cis rs9549367 0.756 rs2302756 chr13:113900197 G/A cg18105134 chr13:113819100 PROZ 0.63 10.86 0.51 8.15e-24 Platelet distribution width; LIHC cis rs10242455 0.571 rs45593341 chr7:99304911 C/A cg18809830 chr7:99032528 PTCD1 -0.83 -6.63 -0.34 1.3100000000000001e-10 Blood metabolite levels; LIHC cis rs17384381 0.906 rs2300639 chr1:85823676 T/A cg16011679 chr1:85725395 C1orf52 0.85 8.79 0.43 7.29e-17 Lobe attachment (rater-scored or self-reported); LIHC trans rs3780486 0.846 rs10738905 chr9:33123627 A/G cg04842962 chr6:43655489 MRPS18A 1.05 24.76 0.8 2.84e-78 IgG glycosylation; LIHC cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg14004847 chr7:1930337 MAD1L1 -0.46 -6.68 -0.34 9.94e-11 Bipolar disorder and schizophrenia; LIHC cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg11645453 chr3:52864694 ITIH4 0.21 5.75 0.3 2.01e-8 Bipolar disorder; LIHC cis rs2834188 0.737 rs2834179 chr21:34679731 A/G cg14352951 chr21:34696688 IFNAR1 0.47 6.51 0.33 2.61e-10 Narcolepsy; LIHC cis rs1008375 0.898 rs4698620 chr4:17587361 C/T cg02297831 chr4:17616191 MED28 0.48 7.33 0.37 1.68e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs916888 0.821 rs199506 chr17:44859031 A/G cg15921436 chr17:44337874 NA -0.67 -6.94 -0.35 1.95e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs473651 0.935 rs477041 chr2:239355995 C/G cg18131467 chr2:239335373 ASB1 -1.07 -20.84 -0.75 7.84e-63 Multiple system atrophy; LIHC cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg06640241 chr16:89574553 SPG7 0.65 10.39 0.49 3.56e-22 Multiple myeloma (IgH translocation); LIHC cis rs9649213 0.593 rs12672092 chr7:97986557 C/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.24e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs10791097 0.694 rs7106684 chr11:130758153 A/T cg14779329 chr11:130786720 SNX19 0.43 6.53 0.33 2.39e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9611565 0.608 rs2003816 chr22:42095140 T/G cg06634786 chr22:41940651 POLR3H 0.56 6.16 0.32 2e-9 Vitiligo; LIHC cis rs116248771 0.739 rs4680448 chr3:158349978 C/A cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.77e-10 diarrhoeal disease at age 2; LIHC cis rs6461049 0.638 rs3778994 chr7:2175855 G/T cg02951883 chr7:2050386 MAD1L1 -0.49 -7.83 -0.39 6.39e-14 Schizophrenia; LIHC cis rs3812831 0.695 rs8000778 chr13:114944310 T/C cg06611532 chr13:114900021 NA 0.41 7.54 0.38 4.25e-13 Schizophrenia; LIHC cis rs2425143 1.000 rs11699044 chr20:34312713 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.6 7.87 0.39 4.58e-14 Blood protein levels; LIHC cis rs4654899 0.758 rs2874367 chr1:21324491 A/C cg08539965 chr1:21396338 EIF4G3 -0.34 -6.26 -0.32 1.15e-9 Superior frontal gyrus grey matter volume; LIHC cis rs34779708 0.897 rs16935880 chr10:35415468 C/G cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7520258 1 rs7520258 chr1:236313127 A/G cg17269430 chr1:236305619 GPR137B 0.85 7.95 0.39 2.78e-14 Response to antipsychotic treatment in schizophrenia (working memory); LIHC cis rs2075371 0.830 rs12669960 chr7:133931782 A/G cg20476274 chr7:133979776 SLC35B4 0.66 9.11 0.44 7.02e-18 Mean platelet volume; LIHC cis rs1799949 0.929 rs799906 chr17:41278116 T/C cg25072359 chr17:41440525 NA 0.38 6.01 0.31 4.72e-9 Menopause (age at onset); LIHC cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.5 0.33 2.86e-10 Bipolar disorder; LIHC cis rs1865760 1.000 rs6938233 chr6:25914077 C/T cg03517284 chr6:25882590 NA -0.37 -5.72 -0.3 2.34e-8 Height; LIHC cis rs9309473 0.950 rs10198549 chr2:73794404 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.94e-10 Metabolite levels; LIHC trans rs7714584 1.000 rs2880791 chr5:150267376 C/A cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs7223966 1.000 rs6504173 chr17:61735056 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.05 0.36 9.83e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2197308 0.765 rs12824529 chr12:37931656 T/C cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs3008870 1.000 rs3008873 chr1:67425770 G/A cg02640540 chr1:67518911 SLC35D1 0.43 5.93 0.31 7.24e-9 Lymphocyte percentage of white cells; LIHC cis rs13108904 0.557 rs1250098 chr4:1238256 A/T cg05025164 chr4:1340916 KIAA1530 -0.66 -9.93 -0.47 1.36e-20 Obesity-related traits; LIHC cis rs2191566 1.000 rs7256908 chr19:44528898 C/T cg20607764 chr19:44506953 ZNF230 -0.42 -6.85 -0.35 3.51e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.95 -10.54 -0.49 1.16e-22 Platelet count; LIHC trans rs61931739 0.500 rs7298322 chr12:34445489 A/T cg26384229 chr12:38710491 ALG10B 0.64 8.06 0.4 1.31e-14 Morning vs. evening chronotype; LIHC cis rs6545883 0.860 rs13023037 chr2:61620989 C/T cg15711740 chr2:61764176 XPO1 0.42 5.91 0.3 8.35e-9 Tuberculosis; LIHC cis rs77633900 0.614 rs280028 chr15:77031466 A/G cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs9300255 0.602 rs1727313 chr12:123640853 C/G cg00376283 chr12:123451042 ABCB9 0.64 6.8 0.34 4.81e-11 Neutrophil percentage of white cells; LIHC trans rs11088226 1.000 rs2833890 chr21:33927886 A/G cg09050820 chr6:167586206 TCP10L2 -0.76 -11.66 -0.53 1.1e-26 Gastritis; LIHC cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg02187348 chr16:89574699 SPG7 0.66 10.47 0.49 1.96e-22 Multiple myeloma (IgH translocation); LIHC cis rs372883 0.600 rs1153276 chr21:30661694 T/C cg24692254 chr21:30365293 RNF160 -0.51 -6.39 -0.33 5.41e-10 Pancreatic cancer; LIHC cis rs62481355 1.000 rs62481355 chr7:127201664 C/T cg25922125 chr7:127225783 GCC1 -0.44 -5.77 -0.3 1.73e-8 Type 2 diabetes; LIHC cis rs72781680 0.898 rs12614616 chr2:23996501 T/G cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs875971 0.862 rs937494 chr7:65764678 T/A cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.03e-40 Aortic root size; LIHC trans rs9531686 0.967 rs9546997 chr13:85547901 G/T cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.3 0.32 9.32e-10 Anorexia nervosa; LIHC trans rs6598955 0.671 rs8564 chr1:26605069 T/C cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs2016586 0.894 rs5995155 chr22:36102700 A/G cg26342177 chr22:36113512 APOL5 -0.37 -6.2 -0.32 1.6e-9 Body mass index; LIHC cis rs3770081 1.000 rs2278087 chr2:86281946 C/T cg01119172 chr2:86362222 SNORD94;PTCD3 0.44 6.03 0.31 4.36e-9 Facial emotion recognition (sad faces); LIHC cis rs4820539 1.000 rs916585 chr22:23469438 G/A cg14186256 chr22:23484241 RTDR1 0.98 21.52 0.76 1.48e-65 Bone mineral density; LIHC cis rs6582630 0.555 rs11182429 chr12:38526679 A/C cg26384229 chr12:38710491 ALG10B 0.63 8.98 0.44 1.8e-17 Drug-induced liver injury (flucloxacillin); LIHC cis rs6582630 0.519 rs7294300 chr12:38277359 C/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs2334880 0.678 rs34400718 chr16:71455852 G/A cg06353428 chr16:71660113 MARVELD3 -0.86 -8.49 -0.42 6.59e-16 Malaria; LIHC cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg03806693 chr22:41940476 POLR3H 0.96 10.29 0.49 7.91e-22 Vitiligo; LIHC cis rs16912285 0.688 rs12805482 chr11:24346955 C/A ch.11.24196551F chr11:24239977 NA 0.72 8.3 0.41 2.5e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs1559088 0.600 rs7255229 chr19:33562807 A/G cg27124370 chr19:33622961 WDR88 0.55 7.87 0.39 4.78e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.42 0.56 1.8e-29 Prudent dietary pattern; LIHC cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg02951883 chr7:2050386 MAD1L1 -0.47 -7.07 -0.36 8.88e-12 Bipolar disorder and schizophrenia; LIHC cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.51 -8.24 -0.41 3.73e-15 Bipolar disorder; LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.1 0.55 2.58e-28 Prudent dietary pattern; LIHC trans rs3960554 0.674 rs112742093 chr7:75800597 T/C cg19862616 chr7:65841803 NCRNA00174 0.61 8.3 0.41 2.45e-15 Eotaxin levels; LIHC cis rs6964587 1.000 rs10236397 chr7:91691601 C/T cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs919433 0.679 rs6708239 chr2:198525084 A/G cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg26338869 chr17:61819248 STRADA 0.61 8.82 0.43 6.02e-17 Prudent dietary pattern; LIHC cis rs9381040 0.610 rs6941090 chr6:41043465 G/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.79 -0.3 1.58e-8 Alzheimer's disease (late onset); LIHC cis rs67311347 1.000 rs897117 chr3:40437294 C/T cg09455208 chr3:40491958 NA -0.29 -5.71 -0.3 2.39e-8 Renal cell carcinoma; LIHC cis rs6952808 0.965 rs11768541 chr7:1894884 G/A cg22963979 chr7:1858916 MAD1L1 -0.44 -6.87 -0.35 3.14e-11 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13789711 chr9:139743225 PHPT1 0.43 6.56 0.33 1.94e-10 Pancreatic cancer; LIHC cis rs2404602 0.735 rs11857327 chr15:76764263 G/C cg03037974 chr15:76606532 NA -0.63 -10.88 -0.51 7.1e-24 Blood metabolite levels; LIHC cis rs763121 0.819 rs5757160 chr22:38989646 T/C cg06022373 chr22:39101656 GTPBP1 0.75 15.06 0.63 1.09e-39 Menopause (age at onset); LIHC cis rs250677 0.687 rs10040624 chr5:148437579 A/G cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs2717559 0.542 rs34147336 chr8:143884869 A/G cg07661805 chr8:143867942 LY6D -0.32 -6.87 -0.35 3.11e-11 Urinary tract infection frequency; LIHC cis rs7552404 1.000 rs441109 chr1:76120430 T/G cg03433033 chr1:76189801 ACADM -0.68 -9.51 -0.46 3.48e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9457247 1.000 rs400176 chr6:167406238 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 9.93 0.47 1.36e-20 Crohn's disease; LIHC cis rs61677309 1.000 rs12577045 chr11:118151446 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.6 0.34 1.53e-10 Lung cancer in ever smokers; LIHC cis rs1062177 1.000 rs41494545 chr5:151235094 A/G cg00977110 chr5:151150581 G3BP1 -0.51 -6.32 -0.32 8.22e-10 Preschool internalizing problems; LIHC cis rs7582180 0.629 rs893416 chr2:100957443 G/A cg14675211 chr2:100938903 LONRF2 0.54 8.58 0.42 3.3e-16 Intelligence (multi-trait analysis); LIHC cis rs2625529 0.824 rs55854204 chr15:72433182 C/T cg16672083 chr15:72433130 SENP8 -0.3 -5.82 -0.3 1.38e-8 Red blood cell count; LIHC cis rs422249 0.896 rs174449 chr11:61640379 A/G cg27386326 chr11:61587980 NA 0.35 6.24 0.32 1.27e-9 Trans fatty acid levels; LIHC cis rs9612 1.000 rs346527 chr19:44259361 A/G cg08581076 chr19:44259116 C19orf61 0.7 8.94 0.44 2.49e-17 Exhaled nitric oxide output; LIHC cis rs7589728 1.000 rs2363731 chr2:88521793 C/T cg04511125 chr2:88470314 THNSL2 0.76 7.09 0.36 7.83e-12 Plasma clusterin levels; LIHC cis rs10791097 0.694 rs4937581 chr11:130740335 T/C cg09137382 chr11:130731461 NA 0.41 6.09 0.31 2.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7119 0.717 rs11632729 chr15:77722006 G/A cg17802220 chr15:77601643 NA -0.37 -6.91 -0.35 2.42e-11 Type 2 diabetes; LIHC cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.85 0.69 8.27e-51 Gut microbiome composition (summer); LIHC cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg00166722 chr3:10149974 C3orf24 0.47 5.73 0.3 2.21e-8 Alzheimer's disease; LIHC cis rs561341 0.883 rs2074102 chr17:30228884 G/A cg13647721 chr17:30228624 UTP6 0.8 7.65 0.38 2.07e-13 Hip circumference adjusted for BMI; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC cis rs801193 1.000 rs2659906 chr7:66165310 T/C cg00343986 chr7:65444356 GUSB 0.39 5.77 0.3 1.76e-8 Aortic root size; LIHC cis rs13108904 0.846 rs3775100 chr4:1225106 T/C cg13395646 chr4:1353034 KIAA1530 -0.42 -6.2 -0.32 1.65e-9 Obesity-related traits; LIHC cis rs10508774 1.000 rs72780316 chr10:32924848 C/G cg01819863 chr10:32635814 EPC1 0.64 5.83 0.3 1.28e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs796364 0.865 rs769948 chr2:200728475 C/A cg23649088 chr2:200775458 C2orf69 0.49 5.85 0.3 1.18e-8 Schizophrenia; LIHC cis rs7296418 0.961 rs10773921 chr12:123541606 C/T cg05973401 chr12:123451056 ABCB9 0.51 8.15 0.4 6.83e-15 Platelet count; LIHC cis rs4919087 1.000 rs7076523 chr10:99089296 T/C cg25902810 chr10:99078978 FRAT1 -0.66 -9.91 -0.47 1.63e-20 Monocyte count; LIHC cis rs17102423 0.588 rs7150646 chr14:65540463 G/T cg16583315 chr14:65563665 MAX -0.39 -7.88 -0.39 4.33e-14 Obesity-related traits; LIHC cis rs7647973 0.626 rs1078341 chr3:49685592 A/G cg03060546 chr3:49711283 APEH 0.63 7.33 0.37 1.72e-12 Menarche (age at onset); LIHC cis rs61677309 0.558 rs7940047 chr11:118142619 C/T cg06090739 chr11:118230722 UBE4A 0.31 6.02 0.31 4.56e-9 Lung cancer in ever smokers; LIHC cis rs9303280 0.806 rs12232498 chr17:38040363 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.72 0.3 2.27e-8 Self-reported allergy; LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg11062466 chr8:58055876 NA -0.51 -7.42 -0.37 9.43e-13 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.64 0.34 1.25e-10 Bipolar disorder; LIHC cis rs7762018 0.607 rs77972667 chr6:170130456 G/C cg19338460 chr6:170058176 WDR27 -0.83 -8.24 -0.41 3.84e-15 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11030122 0.702 rs10500590 chr11:3964724 T/C cg18678763 chr11:4115507 RRM1 -0.57 -8.56 -0.42 3.98e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs6061231 0.958 rs2427304 chr20:60953584 G/A cg24112000 chr20:60950667 NA -0.6 -8.34 -0.41 1.78e-15 Colorectal cancer; LIHC trans rs208520 0.690 rs1885100 chr6:66871047 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.44 -0.42 9.43e-16 Exhaled nitric oxide output; LIHC trans rs1814175 0.791 rs10769625 chr11:49869887 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.15e-11 Height; LIHC cis rs4713118 0.621 rs4713133 chr6:28034041 T/C cg16479474 chr6:28041457 NA 0.47 6.96 0.35 1.73e-11 Parkinson's disease; LIHC cis rs600806 0.815 rs10858094 chr1:109950858 T/C cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.46 -0.37 7.02e-13 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg18404041 chr3:52824283 ITIH1 -0.43 -7.04 -0.36 1.07e-11 Electroencephalogram traits; LIHC cis rs7191700 0.712 rs7187741 chr16:11433103 C/G cg00044050 chr16:11439710 C16orf75 -0.48 -7.1 -0.36 7.39e-12 Multiple sclerosis; LIHC cis rs7904368 0.754 rs17139234 chr10:16849732 G/T cg23933602 chr10:16859644 RSU1 0.61 5.95 0.31 6.66e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs9388451 0.505 rs6920965 chr6:126179111 G/A cg05901451 chr6:126070800 HEY2 -0.47 -8.16 -0.4 6.39e-15 Brugada syndrome; LIHC cis rs5769765 0.646 rs9616205 chr22:50309915 A/T cg26441486 chr22:50317300 CRELD2 0.37 6.3 0.32 9.03e-10 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11234017 chr17:42767172 CCDC43 0.47 7.16 0.36 4.9e-12 Pancreatic cancer; LIHC cis rs2404602 0.583 rs12592501 chr15:76554790 C/A cg22467129 chr15:76604101 ETFA -0.37 -6.26 -0.32 1.16e-9 Blood metabolite levels; LIHC cis rs7264396 0.747 rs2425151 chr20:34394541 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.75 -0.5 1.99e-23 Total cholesterol levels; LIHC cis rs2242116 0.932 rs7646906 chr3:46949379 G/A cg23352942 chr3:46931381 PTH1R -0.3 -7.85 -0.39 5.24e-14 Birth weight; LIHC cis rs11690935 0.788 rs6715929 chr2:172877507 A/G cg13550731 chr2:172543902 DYNC1I2 -0.42 -7.05 -0.36 9.77e-12 Schizophrenia; LIHC cis rs4660306 0.961 rs937290 chr1:45961955 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.63 -7.5 -0.38 5.56e-13 Homocysteine levels; LIHC cis rs3736594 0.513 rs62138965 chr2:27816593 T/C cg27432699 chr2:27873401 GPN1 0.46 6.85 0.35 3.5e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC trans rs11689435 0.925 rs13013662 chr2:218345080 C/G cg13544946 chr9:35729779 TLN1 -0.44 -6.35 -0.32 6.82e-10 Metabolite levels (MHPG); LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg06420487 chr17:61919686 SMARCD2 0.42 5.8 0.3 1.51e-8 Height; LIHC cis rs172166 0.694 rs203893 chr6:28062066 C/A cg25329415 chr6:28076851 NA 0.27 5.71 0.3 2.44e-8 Cardiac Troponin-T levels; LIHC cis rs1538970 0.748 rs11211137 chr1:46013892 T/A cg06784218 chr1:46089804 CCDC17 0.37 5.82 0.3 1.39e-8 Platelet count; LIHC cis rs1577917 0.876 rs12201992 chr6:86618219 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs11718455 1.000 rs9858826 chr3:44031412 C/T cg08738300 chr3:44038990 NA -0.5 -8.88 -0.43 3.88e-17 Coronary artery disease; LIHC cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg18357526 chr6:26021779 HIST1H4A 1.0 14.66 0.62 4.2e-38 Intelligence (multi-trait analysis); LIHC trans rs60843830 1.000 rs17714252 chr2:285471 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.64 9.09 0.44 8.46e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs9942416 0.660 rs4704234 chr5:75001432 A/G cg19683494 chr5:74908142 NA 0.48 6.39 0.33 5.32e-10 Age-related disease endophenotypes; LIHC cis rs2290416 0.681 rs3793371 chr8:144664299 C/T cg08508337 chr8:144660607 NAPRT1 -0.61 -5.8 -0.3 1.49e-8 Attention deficit hyperactivity disorder; LIHC cis rs12986413 0.934 rs6510645 chr19:2158398 T/C cg09261902 chr19:2140048 AP3D1 0.39 6.55 0.33 2.09e-10 Height; LIHC cis rs2228479 0.850 rs11641552 chr16:89838700 C/A cg06558623 chr16:89946397 TCF25 0.88 12.17 0.55 1.43e-28 Skin colour saturation; LIHC cis rs1865760 0.929 rs1436307 chr6:25939723 C/T cg17691542 chr6:26056736 HIST1H1C 0.4 5.95 0.31 6.6e-9 Height; LIHC cis rs116095464 0.558 rs10075018 chr5:239175 G/A cg22857025 chr5:266934 NA -1.48 -18.03 -0.7 1.51e-51 Breast cancer; LIHC cis rs5769765 0.908 rs9616213 chr22:50317851 T/G cg09182678 chr22:50328711 NA -0.4 -5.91 -0.3 8.41e-9 Schizophrenia; LIHC cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg14983838 chr19:29218262 NA 0.5 7.48 0.37 6.37e-13 Methadone dose in opioid dependence; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21512275 chr2:157198069 NA 0.58 8.19 0.4 5.16e-15 Pancreatic cancer; LIHC cis rs4474465 0.688 rs10501429 chr11:78279790 T/G cg02023728 chr11:77925099 USP35 -0.32 -5.72 -0.3 2.3e-8 Alzheimer's disease (survival time); LIHC cis rs7312933 0.524 rs11181465 chr12:42765098 T/G cg17420585 chr12:42539391 GXYLT1 -0.37 -5.94 -0.31 6.93e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9649465 0.967 rs1008539 chr7:123305518 G/A cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.56e-14 Migraine; LIHC cis rs898097 0.607 rs2199111 chr17:80823203 A/G cg15664640 chr17:80829946 TBCD -0.46 -7.65 -0.38 2.02e-13 Breast cancer; LIHC cis rs2404602 0.587 rs17380507 chr15:77235361 C/T cg03037974 chr15:76606532 NA 0.73 14.01 0.6 1.43e-35 Blood metabolite levels; LIHC cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg12379764 chr21:47803548 PCNT -0.59 -8.56 -0.42 3.92e-16 Testicular germ cell tumor; LIHC cis rs600806 0.850 rs11102976 chr1:109917540 G/C cg23091122 chr1:110024289 SYPL2 -0.45 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC cis rs4803468 1.000 rs166925 chr19:41926098 T/C cg09537434 chr19:41945824 ATP5SL -1.03 -21.47 -0.76 2.26e-65 Height; LIHC cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC trans rs7246657 0.943 rs1373991 chr19:37838911 T/C cg10208301 chr11:6592745 DNHD1 0.48 6.96 0.35 1.71e-11 Coronary artery calcification; LIHC cis rs875971 0.619 rs12533585 chr7:65984605 G/C cg18876405 chr7:65276391 NA 0.44 7.7 0.38 1.44e-13 Aortic root size; LIHC cis rs6121246 0.909 rs8126355 chr20:30332660 C/T cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC cis rs45430 1.000 rs364525 chr21:42745578 A/G cg06102954 chr21:42741788 MX2 -0.38 -6.49 -0.33 2.94e-10 Melanoma; LIHC cis rs6430585 0.528 rs79826902 chr2:136670419 G/A cg25344623 chr2:136566232 LCT -0.38 -6.1 -0.31 2.88e-9 Corneal structure; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05098230 chr7:92076734 GATAD1 -0.57 -6.56 -0.33 2.02e-10 Systolic blood pressure; LIHC cis rs8049603 0.524 rs10492790 chr16:23076410 C/T cg16484020 chr16:23217411 SCNN1G -0.23 -5.88 -0.3 9.67e-9 Multiple sclerosis; LIHC cis rs8067354 0.958 rs2777889 chr17:57848006 A/G cg02344993 chr17:57696989 CLTC 0.52 8.25 0.41 3.51e-15 Hemoglobin concentration; LIHC cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg26531700 chr6:26746687 NA 0.38 6.19 0.32 1.7e-9 Intelligence (multi-trait analysis); LIHC cis rs1997103 1.000 rs6968966 chr7:55411356 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13053135 chr2:234359932 DGKD 0.42 6.42 0.33 4.56e-10 Longevity; LIHC cis rs244731 0.919 rs12652509 chr5:176626441 A/G cg16006841 chr5:176797999 RGS14 -0.61 -5.9 -0.3 8.67e-9 Urate levels in lean individuals; LIHC cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg26939375 chr7:64535504 NA 0.48 7.24 0.36 3.07e-12 Calcium levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06790019 chr1:44435457 DPH2 0.42 6.15 0.32 2.14e-9 Lung function (FEV1/FVC); LIHC cis rs4803468 1.000 rs2241711 chr19:41911980 T/C cg09537434 chr19:41945824 ATP5SL -1.01 -21.33 -0.76 8.44e-65 Height; LIHC trans rs875971 0.545 rs73152714 chr7:65999628 G/A cg26939375 chr7:64535504 NA 0.4 6.31 0.32 8.63e-10 Aortic root size; LIHC cis rs1348850 0.958 rs4243390 chr2:178468008 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.39 0.52 1.09e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10463316 0.604 rs28744577 chr5:150768983 A/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.69 -0.34 9.29e-11 Metabolite levels (Pyroglutamine); LIHC cis rs2346177 0.554 rs36006825 chr2:46708945 G/T cg02822958 chr2:46747628 ATP6V1E2 0.52 7.86 0.39 5.11e-14 HDL cholesterol; LIHC cis rs9549328 0.878 rs9577407 chr13:113639671 G/A cg18289306 chr13:113640169 MCF2L 0.43 6.98 0.35 1.5e-11 Systolic blood pressure; LIHC cis rs66573146 1.000 rs6838042 chr4:6973049 G/T cg00086871 chr4:6988644 TBC1D14 0.85 6.11 0.31 2.71e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs10089 0.953 rs13358455 chr5:127365786 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.66 0.34 1.08e-10 Ileal carcinoids; LIHC cis rs5769707 0.967 rs739248 chr22:50025205 T/C cg01652190 chr22:50026171 C22orf34 -0.3 -7.01 -0.35 1.28e-11 Monocyte count;Monocyte percentage of white cells; LIHC trans rs10411161 0.702 rs6509591 chr19:52391940 A/T cg22319618 chr22:45562946 NUP50 -0.61 -8.27 -0.41 3.02e-15 Breast cancer; LIHC cis rs10197940 0.532 rs13425170 chr2:152387112 A/C cg06191203 chr2:152266755 RIF1 -0.41 -6.64 -0.34 1.24e-10 Lung cancer; LIHC trans rs62103177 0.525 rs62101233 chr18:77724288 C/T cg05926928 chr17:57297772 GDPD1 0.61 6.72 0.34 7.44e-11 Opioid sensitivity; LIHC cis rs5769707 0.749 rs8137251 chr22:50036669 G/A cg01652190 chr22:50026171 C22orf34 -0.32 -7.39 -0.37 1.12e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs5769765 1.000 rs910800 chr22:50278642 C/T cg26441486 chr22:50317300 CRELD2 -0.35 -6.32 -0.32 7.96e-10 Schizophrenia; LIHC cis rs67981189 0.593 rs2877708 chr14:71484126 C/G cg15816911 chr14:71606274 NA 0.4 6.35 0.32 6.99e-10 Schizophrenia; LIHC trans rs1814175 0.754 rs7103235 chr11:49699191 A/G cg18944383 chr4:111397179 ENPEP 0.34 8.18 0.4 5.47e-15 Height; LIHC trans rs3780486 0.846 rs7865745 chr9:33140976 A/G cg04842962 chr6:43655489 MRPS18A -1.07 -25.45 -0.81 6.64e-81 IgG glycosylation; LIHC cis rs3820068 0.705 rs57971278 chr1:15838604 G/A cg17385448 chr1:15911702 AGMAT 0.39 6.51 0.33 2.75e-10 Systolic blood pressure; LIHC cis rs16854884 0.710 rs9829796 chr3:143801416 C/T cg06585982 chr3:143692056 C3orf58 0.42 5.95 0.31 6.79e-9 Economic and political preferences (feminism/equality); LIHC cis rs4665809 0.941 rs2289021 chr2:26362515 A/C cg04944784 chr2:26401820 FAM59B 0.67 8.47 0.42 7.28e-16 Gut microbiome composition (summer); LIHC cis rs11122272 0.735 rs2572252 chr1:231513653 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs6762 0.719 rs7936806 chr11:839186 G/C cg15787769 chr11:842744 TSPAN4;POLR2L -0.62 -7.46 -0.37 7.25e-13 Mean platelet volume; LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs7666738 0.716 rs35195511 chr4:98859660 G/A cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs13392177 0.660 rs12988046 chr2:219073804 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.54 -7.6 -0.38 2.92e-13 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs1801251 1.000 rs283468 chr2:233658309 C/T cg08000102 chr2:233561755 GIGYF2 0.77 11.67 0.53 1.02e-26 Coronary artery disease; LIHC cis rs7772486 0.875 rs7766595 chr6:146364507 A/T cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.21e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2637266 0.875 rs115333453 chr10:78369011 G/A cg18941641 chr10:78392320 NA 0.27 5.73 0.3 2.2e-8 Pulmonary function; LIHC cis rs3815308 0.530 rs12983546 chr19:2195065 G/T cg09261902 chr19:2140048 AP3D1 0.37 6.11 0.31 2.79e-9 Breast cancer; LIHC cis rs77861329 1.000 rs9847092 chr3:52199453 T/C cg08692210 chr3:52188851 WDR51A 0.81 7.77 0.39 9.13e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs4727027 0.870 rs13237714 chr7:148884083 A/G cg23583168 chr7:148888333 NA -0.74 -10.54 -0.5 1.15e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs67478160 0.609 rs1547604 chr14:104270659 A/T cg01849466 chr14:104193079 ZFYVE21 -0.49 -8.41 -0.41 1.11e-15 Schizophrenia; LIHC cis rs3093024 0.595 rs4458654 chr6:167476068 A/C cg12798992 chr6:167411361 FGFR1OP 0.47 6.93 0.35 2.07e-11 Rheumatoid arthritis; LIHC trans rs208515 0.525 rs12191500 chr6:66668681 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.79 8.91 0.43 3.18e-17 Exhaled nitric oxide levels; LIHC cis rs2637266 1.000 rs2894337 chr10:78344871 C/T cg18941641 chr10:78392320 NA 0.29 6.22 0.32 1.43e-9 Pulmonary function; LIHC cis rs11168351 0.591 rs4258439 chr12:48468652 A/G cg21466736 chr12:48725269 NA 0.33 5.95 0.31 6.81e-9 Bipolar disorder and schizophrenia; LIHC cis rs4975616 0.869 rs370348 chr5:1331219 A/G cg26373071 chr5:1325741 CLPTM1L 0.35 5.73 0.3 2.25e-8 Lung cancer; LIHC cis rs10791097 0.720 rs6590518 chr11:130733530 C/T cg14779329 chr11:130786720 SNX19 0.38 5.82 0.3 1.34e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg21782813 chr7:2030301 MAD1L1 0.43 7.02 0.36 1.17e-11 Bipolar disorder and schizophrenia; LIHC trans rs11098499 0.697 rs4373140 chr4:120307698 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs11190604 1.000 rs11190557 chr10:102209369 G/A cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs1005277 0.505 rs200935 chr10:38132810 T/A cg23533926 chr12:111358616 MYL2 -0.33 -6.47 -0.33 3.34e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2228479 0.702 rs62053701 chr16:89860584 G/A cg00800038 chr16:89945340 TCF25 -0.61 -8.68 -0.42 1.69e-16 Skin colour saturation; LIHC cis rs896854 0.517 rs10112447 chr8:95955701 C/T cg16049864 chr8:95962084 TP53INP1 -0.49 -7.93 -0.39 3.04e-14 Type 2 diabetes; LIHC cis rs11690935 0.632 rs62184165 chr2:172558328 A/G cg13550731 chr2:172543902 DYNC1I2 0.64 11.97 0.54 8.24e-28 Schizophrenia; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg06577708 chr3:64008893 PSMD6 -0.44 -6.36 -0.33 6.59e-10 Triglycerides; LIHC cis rs3857067 0.806 rs4560373 chr4:95113229 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs25645 0.771 rs11078936 chr17:38197914 T/C cg17467752 chr17:38218738 THRA -0.54 -9.18 -0.44 4.33e-18 Myeloid white cell count; LIHC cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg16325326 chr1:53192061 ZYG11B -0.5 -8.77 -0.43 8.74e-17 Monocyte count; LIHC cis rs763121 0.657 rs5995603 chr22:39040733 G/A cg14440974 chr22:39074834 NA -0.41 -6.31 -0.32 8.88e-10 Menopause (age at onset); LIHC cis rs35110281 0.626 rs162389 chr21:44936227 T/C cg21573476 chr21:45109991 RRP1B -0.42 -7.77 -0.39 9.38e-14 Mean corpuscular volume; LIHC cis rs10779751 0.727 rs4845852 chr1:11233559 C/T cg08854313 chr1:11322531 MTOR 0.85 14.23 0.61 2e-36 Body mass index; LIHC cis rs8078723 0.677 rs8073254 chr17:38149350 C/G cg17467752 chr17:38218738 THRA -0.6 -10.25 -0.48 1.14e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs9682041 0.696 rs10936627 chr3:170104406 C/T cg11886554 chr3:170076028 SKIL 0.63 5.84 0.3 1.23e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC trans rs4566648 0.593 rs10002954 chr4:84177179 G/A cg06219686 chr17:29421884 NF1 -0.52 -6.12 -0.31 2.53e-9 Monocyte count; LIHC cis rs611744 0.967 rs596245 chr8:109240822 G/A cg18478394 chr8:109455254 TTC35 0.38 6.54 0.33 2.29e-10 Dupuytren's disease; LIHC cis rs7131987 0.650 rs10843377 chr12:29437053 C/G cg00204748 chr12:29376779 FAR2 -0.41 -7.32 -0.37 1.84e-12 QT interval; LIHC cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg22618164 chr12:122356400 WDR66 0.54 9.11 0.44 7.22e-18 Mean corpuscular volume; LIHC cis rs7843479 0.601 rs2306645 chr8:21845428 C/T cg17168535 chr8:21777572 XPO7 -0.5 -8.6 -0.42 2.95e-16 Mean corpuscular volume; LIHC cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.03 -0.44 1.28e-17 Bipolar disorder; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19819135 chr1:70710422 SFRS11 0.42 6.21 0.32 1.53e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs60871478 0.636 rs4721834 chr7:896142 C/T cg05535760 chr7:792225 HEATR2 -0.81 -6.59 -0.34 1.67e-10 Cerebrospinal P-tau181p levels; LIHC cis rs6840360 0.593 rs1366907 chr4:152682749 T/C cg22705602 chr4:152727874 NA -0.4 -8.39 -0.41 1.29e-15 Intelligence (multi-trait analysis); LIHC trans rs7618501 0.633 rs2353579 chr3:50027774 C/T cg21659725 chr3:3221576 CRBN 0.67 10.88 0.51 7.31e-24 Intelligence (multi-trait analysis); LIHC cis rs2075371 0.966 rs722657 chr7:133994956 T/C cg11752832 chr7:134001865 SLC35B4 0.52 7.63 0.38 2.29e-13 Mean platelet volume; LIHC cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC cis rs1707322 0.752 rs12062535 chr1:46222880 G/A cg06784218 chr1:46089804 CCDC17 0.42 7.49 0.38 6.03e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19884546 chr22:38082237 NOL12 0.43 6.58 0.34 1.75e-10 Cognitive function; LIHC cis rs9517313 0.591 rs9554480 chr13:99221138 T/A cg20487152 chr13:99095054 FARP1 -0.38 -6.2 -0.32 1.64e-9 Neuroticism; LIHC cis rs992157 0.560 rs4674275 chr2:219097738 G/A cg00012203 chr2:219082015 ARPC2 -0.88 -15.33 -0.64 9.23e-41 Colorectal cancer; LIHC cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg18876405 chr7:65276391 NA 0.56 9.46 0.46 5.21e-19 Aortic root size; LIHC cis rs10751667 0.961 rs6597953 chr11:991099 G/A cg06064525 chr11:970664 AP2A2 -0.49 -12.17 -0.55 1.5e-28 Alzheimer's disease (late onset); LIHC cis rs79149102 0.579 rs3910748 chr15:75318652 A/G cg09165964 chr15:75287851 SCAMP5 -0.61 -8.18 -0.4 5.65e-15 Lung cancer; LIHC trans rs11689435 0.925 rs34042566 chr2:218352970 G/A cg13544946 chr9:35729779 TLN1 -0.45 -6.36 -0.33 6.42e-10 Metabolite levels (MHPG); LIHC cis rs9649213 0.555 rs6968193 chr7:97915902 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs748404 0.560 rs572837 chr15:43823813 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.37 6.12 0.31 2.62e-9 Lung cancer; LIHC cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg24549020 chr5:56110836 MAP3K1 0.53 6.89 0.35 2.76e-11 Initial pursuit acceleration; LIHC cis rs7715806 0.500 rs10515213 chr5:74980572 C/T cg00601450 chr5:74908170 NA -0.59 -7.12 -0.36 6.53e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9309473 0.583 rs11899517 chr2:73573261 A/G cg20560298 chr2:73613845 ALMS1 -0.43 -6.92 -0.35 2.19e-11 Metabolite levels; LIHC cis rs11190604 0.767 rs4919458 chr10:102177728 G/A cg07080220 chr10:102295463 HIF1AN -0.46 -6.86 -0.35 3.15e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs561341 0.623 rs4795665 chr17:30233657 C/T cg13647721 chr17:30228624 UTP6 0.75 8.24 0.41 3.59e-15 Hip circumference adjusted for BMI; LIHC cis rs4073582 0.595 rs474005 chr11:66033301 C/T cg16950941 chr11:66035639 RAB1B 0.6 9.12 0.44 6.67e-18 Gout; LIHC cis rs12791968 1.000 rs10838397 chr11:45009133 A/G cg11846598 chr11:44996168 LOC221122 0.44 7.85 0.39 5.29e-14 Inhibitory control; LIHC cis rs7772486 0.875 rs13204280 chr6:146415368 T/C cg23711669 chr6:146136114 FBXO30 0.58 9.92 0.47 1.49e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2901460 0.509 rs66481227 chr2:62117600 C/T cg02183531 chr2:62113199 CCT4 -0.43 -6.26 -0.32 1.16e-9 Mean corpuscular volume; LIHC cis rs4650994 0.593 rs12735140 chr1:178544218 C/A cg05350800 chr1:178550844 NA -0.35 -7.64 -0.38 2.26e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs797680 0.856 rs11164902 chr1:93778794 A/G cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.67e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs10861342 1.000 rs10861354 chr12:105524294 T/C cg23923672 chr12:105501055 KIAA1033 0.69 8.59 0.42 3.21e-16 IgG glycosylation; LIHC cis rs743757 1.000 rs2236955 chr3:50429876 G/A cg08207895 chr3:50388901 TUSC4;CYB561D2 0.44 6.63 0.34 1.34e-10 Diastolic blood pressure; LIHC cis rs6430585 0.527 rs6753232 chr2:136436317 C/T cg07169764 chr2:136633963 MCM6 -0.67 -8.66 -0.42 1.89e-16 Corneal structure; LIHC cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 7.26 0.37 2.61e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs1707322 0.826 rs10890349 chr1:46249955 T/C cg03146154 chr1:46216737 IPP 0.52 8.44 0.41 9.43e-16 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3806843 0.864 rs2531343 chr5:140129346 A/G cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs3008870 0.583 rs2147838 chr1:67399466 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.87 13.29 0.58 8.66e-33 Lymphocyte percentage of white cells; LIHC cis rs9916302 0.706 rs9893735 chr17:37469858 A/C cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg17310611 chr1:113615709 LRIG2 -0.54 -6.14 -0.32 2.29e-9 Bronchial neuroendocrine tumor; LIHC cis rs12477438 0.520 rs11678456 chr2:99708237 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.33 0.64 9.41e-41 Chronic sinus infection; LIHC cis rs1707322 0.721 rs12037803 chr1:46156492 A/G cg03146154 chr1:46216737 IPP 0.6 10.26 0.49 1.04e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2412488 0.854 rs12511088 chr4:54363262 G/A cg22241045 chr4:54363911 LNX1 0.46 7.64 0.38 2.25e-13 DNA methylation (variation); LIHC cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg27286337 chr10:134555280 INPP5A 0.93 13.32 0.58 6.93e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7927771 1.000 rs4752857 chr11:47655752 C/T cg20135002 chr11:47629003 NA -0.58 -10.13 -0.48 2.9e-21 Subjective well-being; LIHC cis rs67311347 0.866 rs56331709 chr3:40356558 A/C cg18306943 chr3:40428807 ENTPD3 0.35 5.72 0.3 2.3e-8 Renal cell carcinoma; LIHC cis rs3008870 0.959 rs2815359 chr1:67494374 T/C cg02640540 chr1:67518911 SLC35D1 0.45 6.19 0.32 1.69e-9 Lymphocyte percentage of white cells; LIHC cis rs7577696 0.597 rs13006495 chr2:32355490 C/T cg02381751 chr2:32503542 YIPF4 -0.44 -6.14 -0.31 2.34e-9 Inflammatory biomarkers; LIHC cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg07424592 chr7:64974309 NA 0.75 8.59 0.42 3.09e-16 Diabetic kidney disease; LIHC cis rs7267979 1.000 rs2258563 chr20:25273435 C/T cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg04234412 chr22:24373322 LOC391322 0.77 10.8 0.5 1.34e-23 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg08645402 chr16:4508243 NA 0.41 7.68 0.38 1.71e-13 Schizophrenia; LIHC cis rs16866061 1.000 rs12470077 chr2:225334971 T/C cg12698349 chr2:225449008 CUL3 0.73 12.77 0.57 8.21e-31 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs926392 0.666 rs912179 chr20:37710775 G/A cg16355469 chr20:37678765 NA 0.51 7.39 0.37 1.16e-12 Dialysis-related mortality; LIHC cis rs6748734 1.000 rs4675868 chr2:241828542 A/C cg09990169 chr2:241835740 C2orf54 -0.67 -9.56 -0.46 2.34e-19 Urinary metabolites; LIHC cis rs9616064 0.557 rs9616085 chr22:47045556 T/A cg05621596 chr22:47072043 GRAMD4 -0.68 -10.32 -0.49 6.49e-22 Urate levels in obese individuals; LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg21724239 chr8:58056113 NA 0.59 7.63 0.38 2.42e-13 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg08219700 chr8:58056026 NA 0.53 6.86 0.35 3.17e-11 Developmental language disorder (linguistic errors); LIHC cis rs4237845 0.804 rs10877034 chr12:58286444 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.43 5.94 0.31 6.9e-9 Intelligence (multi-trait analysis); LIHC cis rs28374715 0.627 rs28516832 chr15:41367036 G/A cg18705301 chr15:41695430 NDUFAF1 -0.92 -9.51 -0.46 3.53e-19 Ulcerative colitis; LIHC cis rs2637266 1.000 rs2579747 chr10:78327759 C/T cg18941641 chr10:78392320 NA 0.28 5.91 0.3 8.28e-9 Pulmonary function; LIHC cis rs61863818 0.557 rs7919862 chr10:99149964 C/T cg06359132 chr10:99160096 RRP12 0.35 5.78 0.3 1.67e-8 Monocyte percentage of white cells; LIHC cis rs9303401 1.000 rs7218362 chr17:56888299 A/G cg25039879 chr17:56429692 SUPT4H1 0.53 7.32 0.37 1.76e-12 Cognitive test performance; LIHC cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg00750074 chr16:89608354 SPG7 -0.49 -7.7 -0.38 1.48e-13 Multiple myeloma (IgH translocation); LIHC cis rs7487075 0.558 rs3847985 chr12:46655287 G/A cg15584813 chr12:47219626 SLC38A4 0.32 5.79 0.3 1.63e-8 Itch intensity from mosquito bite; LIHC trans rs8022179 0.580 rs6575979 chr14:103841018 A/G cg17675199 chr6:35436792 RPL10A 0.37 7.36 0.37 1.4e-12 Monocyte count; LIHC cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg13271783 chr10:134563150 INPP5A -0.55 -6.44 -0.33 4.07e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs56235845 0.694 rs6876677 chr5:176755342 T/C cg17509989 chr5:176798049 RGS14 0.61 7.78 0.39 8.51e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs7020830 0.928 rs11544336 chr9:37089150 A/G cg14294708 chr9:37120828 ZCCHC7 1.14 24.9 0.8 8.31e-79 Schizophrenia; LIHC cis rs9790314 0.690 rs1903423 chr3:160842252 A/G cg03342759 chr3:160939853 NMD3 -0.73 -11.2 -0.52 5.29e-25 Morning vs. evening chronotype; LIHC cis rs10463316 0.928 rs4958451 chr5:150740007 T/C cg03212797 chr5:150827313 SLC36A1 -0.48 -7.14 -0.36 5.58e-12 Metabolite levels (Pyroglutamine); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15238519 chr22:50683529 TUBGCP6 -0.44 -6.16 -0.32 2.04e-9 Systolic blood pressure; LIHC cis rs4919694 1.000 rs11191473 chr10:104710710 C/G cg04362960 chr10:104952993 NT5C2 1.13 8.8 0.43 6.86e-17 Arsenic metabolism; LIHC cis rs6120849 0.663 rs11698868 chr20:33549946 C/T cg24642439 chr20:33292090 TP53INP2 0.66 7.75 0.39 1.06e-13 Protein C levels; LIHC cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg00750074 chr16:89608354 SPG7 -0.53 -8.57 -0.42 3.67e-16 Multiple myeloma (IgH translocation); LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.59 8.38 0.41 1.38e-15 Lymphocyte counts; LIHC cis rs2637030 0.559 rs256105 chr5:53013889 T/C cg06476337 chr5:52856530 NDUFS4 0.42 6.73 0.34 6.99e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs2933343 0.729 rs6790091 chr3:128608751 G/C cg25356066 chr3:128598488 ACAD9 0.55 7.7 0.38 1.51e-13 IgG glycosylation; LIHC cis rs9467773 0.565 rs4343916 chr6:26522675 A/T cg09904177 chr6:26538194 HMGN4 0.53 8.8 0.43 7.1e-17 Intelligence (multi-trait analysis); LIHC cis rs1555322 0.505 rs591590 chr20:33866028 A/G cg17927777 chr20:33865990 NA -0.55 -6.41 -0.33 4.88e-10 Attention deficit hyperactivity disorder; LIHC cis rs2834188 0.889 rs1467849 chr21:34682069 G/T cg14352951 chr21:34696688 IFNAR1 0.48 6.73 0.34 7.25e-11 Narcolepsy; LIHC cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg26939375 chr7:64535504 NA 0.48 7.22 0.36 3.46e-12 Aortic root size; LIHC cis rs2279817 0.913 rs2270979 chr1:18023290 C/T cg21791023 chr1:18019539 ARHGEF10L 0.43 6.62 0.34 1.36e-10 Neuroticism; LIHC cis rs1003719 0.715 rs9974494 chr21:38566566 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.21 -0.48 1.57e-21 Eye color traits; LIHC cis rs941408 1.000 rs1736176 chr19:2790394 G/A cg06609049 chr19:2785107 THOP1 0.55 9.6 0.46 1.74e-19 Total cholesterol levels; LIHC cis rs7909074 0.831 rs2065466 chr10:45384047 T/C cg04218760 chr10:45406644 TMEM72 -0.24 -7.38 -0.37 1.23e-12 Mean corpuscular volume; LIHC cis rs12579753 0.956 rs7959951 chr12:82231132 T/C cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs826838 0.967 rs11183577 chr12:38781887 A/G cg13010199 chr12:38710504 ALG10B 0.65 7.72 0.39 1.28e-13 Heart rate; LIHC cis rs2710642 0.564 rs6545963 chr2:62822891 C/T cg17519650 chr2:63277830 OTX1 -0.45 -7.07 -0.36 8.99e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs10911232 0.507 rs10737239 chr1:183030170 A/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.53 0.49 1.21e-22 Hypertriglyceridemia; LIHC trans rs1864585 0.552 rs73208794 chr8:10681248 C/G cg26278703 chr11:58910052 FAM111A 0.72 6.57 0.33 1.84e-10 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs6967414 0.792 rs6954012 chr7:6755724 A/C cg00387323 chr7:6746715 ZNF12 0.65 7.19 0.36 3.99e-12 Hematocrit;Hemoglobin concentration; LIHC trans rs6500602 0.789 rs2404546 chr16:4479734 C/G cg05791018 chr13:19965014 NA -0.27 -6.2 -0.32 1.62e-9 Schizophrenia; LIHC cis rs826838 0.967 rs826855 chr12:39114888 T/C cg26384229 chr12:38710491 ALG10B -0.64 -9.46 -0.46 5.03e-19 Heart rate; LIHC cis rs11229555 0.645 rs10896785 chr11:58233395 G/A cg15696309 chr11:58395628 NA -0.62 -7.15 -0.36 5.27e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs12744310 0.943 rs12027685 chr1:41756298 G/A cg03962019 chr1:41807865 NA 0.38 6.1 0.31 2.82e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg18230493 chr5:56204884 C5orf35 -0.44 -6.13 -0.31 2.48e-9 Initial pursuit acceleration; LIHC cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC cis rs7618501 0.633 rs11130234 chr3:50024758 G/T cg24110177 chr3:50126178 RBM5 -0.48 -7.66 -0.38 1.89e-13 Intelligence (multi-trait analysis); LIHC cis rs17854409 0.803 rs1063247 chr20:61472118 C/G cg05147244 chr20:61493195 TCFL5 1.23 10.89 0.51 6.79e-24 Obesity-related traits; LIHC cis rs600806 0.888 rs10858084 chr1:109882250 T/A cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.2 -0.32 1.61e-9 Intelligence (multi-trait analysis); LIHC cis rs921968 0.643 rs524012 chr2:219433273 T/G cg18887096 chr2:219472410 PLCD4 0.35 6.26 0.32 1.13e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs2243480 1.000 rs160639 chr7:65579987 C/G cg10756647 chr7:56101905 PSPH 1.07 13.36 0.59 4.62e-33 Diabetic kidney disease; LIHC cis rs1775715 1.000 rs1251355 chr10:32290146 C/G cg14930904 chr10:32216787 ARHGAP12 0.4 7.2 0.36 3.85e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs10751667 0.961 rs6597971 chr11:928598 T/A ch.11.42038R chr11:967971 AP2A2 0.57 10.49 0.49 1.7e-22 Alzheimer's disease (late onset); LIHC cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg18252515 chr7:66147081 NA 1.28 16.98 0.68 2.52e-47 Diabetic kidney disease; LIHC cis rs12893668 0.703 rs7140568 chr14:104041374 C/T cg24130564 chr14:104152367 KLC1 -0.54 -8.8 -0.43 6.79e-17 Reticulocyte count; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg11494091 chr17:61959527 GH2 0.44 8.17 0.4 6.08e-15 Prudent dietary pattern; LIHC cis rs561341 0.883 rs1034626 chr17:30219500 C/G cg13647721 chr17:30228624 UTP6 -0.73 -7.22 -0.36 3.35e-12 Hip circumference adjusted for BMI; LIHC cis rs2242420 0.920 rs6679565 chr1:21962551 A/G cg18150885 chr1:21978612 RAP1GAP 0.46 5.88 0.3 9.92e-9 Hematological and biochemical traits; LIHC cis rs910316 0.737 rs175424 chr14:75626257 T/C cg11812906 chr14:75593930 NEK9 -0.73 -13.52 -0.59 1.16e-33 Height; LIHC cis rs2251381 0.778 rs2245021 chr21:30546841 C/T cg24692254 chr21:30365293 RNF160 0.72 10.18 0.48 1.95e-21 Selective IgA deficiency; LIHC cis rs10751667 0.643 rs7395592 chr11:934094 C/G cg10932868 chr11:921992 NA 0.39 7.47 0.37 6.59e-13 Alzheimer's disease (late onset); LIHC cis rs1568889 0.877 rs34351528 chr11:28304293 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.85 0.35 3.4e-11 Bipolar disorder; LIHC cis rs7224685 0.906 rs2304586 chr17:4098998 A/G cg09695851 chr17:3907499 NA 0.63 8.26 0.41 3.18e-15 Type 2 diabetes; LIHC cis rs6088590 0.965 rs13040449 chr20:33358901 T/A cg06115741 chr20:33292138 TP53INP2 0.61 8.46 0.42 8.08e-16 Coronary artery disease; LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs1799949 0.827 rs74252763 chr17:41402020 C/T cg10360323 chr17:41437877 NA 0.41 5.9 0.3 8.74e-9 Menopause (age at onset); LIHC cis rs311392 0.966 rs404354 chr8:55087196 A/G cg11783602 chr8:55087084 NA -0.34 -6.57 -0.33 1.92e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs797680 0.856 rs1335679 chr1:93645182 C/T cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.87 -0.3 1.03e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs11758351 0.866 rs55815656 chr6:26207303 G/A cg06951627 chr6:26196580 NA 0.53 6.27 0.32 1.07e-9 Gout;Renal underexcretion gout; LIHC cis rs12497850 0.863 rs4858799 chr3:48728204 G/C cg07636037 chr3:49044803 WDR6 0.81 13.62 0.59 4.64e-34 Parkinson's disease; LIHC cis rs911119 0.955 rs6114201 chr20:23607231 T/A cg16589663 chr20:23618590 CST3 0.71 7.51 0.38 5.15e-13 Chronic kidney disease; LIHC trans rs1005277 0.579 rs2504148 chr10:38400788 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs17095355 1.000 rs12259261 chr10:111725145 A/G cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.84 -0.3 1.21e-8 Biliary atresia; LIHC cis rs17685 0.753 rs4573217 chr7:75733946 G/A cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.37e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35306767 0.714 rs11250228 chr10:1074887 A/G cg20503657 chr10:835505 NA 0.55 6.09 0.31 3.12e-9 Eosinophil percentage of granulocytes; LIHC cis rs7086627 0.515 rs11202957 chr10:82209592 A/G cg00277334 chr10:82204260 NA -0.85 -14.17 -0.61 3.43e-36 Post bronchodilator FEV1; LIHC cis rs7666738 0.830 rs9995386 chr4:98907826 T/C cg05340658 chr4:99064831 C4orf37 0.65 11.92 0.54 1.29e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs9814567 1.000 rs11919350 chr3:134235970 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs700651 0.789 rs2196176 chr2:198904914 A/G cg00792783 chr2:198669748 PLCL1 0.46 6.55 0.33 2.06e-10 Intracranial aneurysm; LIHC cis rs1355223 0.583 rs2915238 chr11:34884405 C/A cg11058730 chr11:34937778 PDHX;APIP 0.77 14.12 0.61 5.45e-36 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs4319547 0.737 rs10846920 chr12:122943231 C/T cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.57 -0.38 3.55e-13 Body mass index; LIHC cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg06481639 chr22:41940642 POLR3H -0.61 -5.9 -0.3 8.58e-9 Vitiligo; LIHC cis rs7224737 0.957 rs6503687 chr17:40295397 G/A cg20291162 chr17:40259547 DHX58 -0.4 -6.38 -0.33 5.88e-10 Fibrinogen levels; LIHC cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs1983891 1.000 rs4714485 chr6:41536587 T/G cg15051332 chr6:41514432 FOXP4 0.41 5.74 0.3 2.05e-8 Prostate cancer; LIHC cis rs6977660 1.000 rs10240227 chr7:19823188 T/C cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC trans rs6952808 0.723 rs60995052 chr7:2030007 G/C cg04565464 chr8:145669602 NFKBIL2 0.4 6.69 0.34 9.34e-11 Bipolar disorder and schizophrenia; LIHC cis rs2455601 1.000 rs11042108 chr11:8906021 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -6.66 -0.34 1.08e-10 Schizophrenia; LIHC cis rs7572733 0.514 rs700686 chr2:198721054 G/A cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg05185784 chr16:90016020 DEF8 -0.49 -6.28 -0.32 1.01e-9 Skin colour saturation; LIHC cis rs17818399 0.708 rs13000706 chr2:46838247 C/G cg02822958 chr2:46747628 ATP6V1E2 0.38 6.15 0.32 2.21e-9 Height; LIHC cis rs2737618 0.674 rs2821334 chr1:200093887 G/T cg21825944 chr1:200113062 NR5A2 -0.46 -7.74 -0.39 1.15e-13 Uric acid levels; LIHC cis rs10089 1.000 rs10061367 chr5:127449021 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.03e-11 Ileal carcinoids; LIHC cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.65e-9 Menopause (age at onset); LIHC cis rs11098499 0.505 rs75122014 chr4:120362426 G/C cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs6424115 1.000 rs6424115 chr1:24153231 A/G cg10978503 chr1:24200527 CNR2 -0.38 -9.1 -0.44 7.34e-18 Immature fraction of reticulocytes; LIHC cis rs739401 0.611 rs2239900 chr11:3030992 C/T cg05729581 chr11:3078854 CARS -0.46 -6.64 -0.34 1.21e-10 Longevity; LIHC cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg03806693 chr22:41940476 POLR3H -1.14 -13.43 -0.59 2.6e-33 Vitiligo; LIHC cis rs7523273 0.606 rs1970530 chr1:207924066 G/A cg22525895 chr1:207977042 MIR29B2 0.66 10.52 0.49 1.36e-22 Schizophrenia; LIHC cis rs7945705 0.967 rs10840148 chr11:8923528 C/T cg12365402 chr11:9010492 NRIP3 0.31 7.91 0.39 3.7e-14 Hemoglobin concentration; LIHC cis rs2841277 0.646 rs2819419 chr14:105406238 A/C cg21017887 chr14:105400489 NA 0.66 12.3 0.55 4.76e-29 Rheumatoid arthritis; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg06420487 chr17:61919686 SMARCD2 0.44 5.95 0.31 6.77e-9 Height; LIHC trans rs11098499 0.909 rs2127821 chr4:120394535 T/C cg25214090 chr10:38739885 LOC399744 0.58 9.64 0.46 1.33e-19 Corneal astigmatism; LIHC cis rs60871478 0.704 rs62432895 chr7:822050 C/G cg05535760 chr7:792225 HEATR2 0.78 11.14 0.52 8.22e-25 Cerebrospinal P-tau181p levels; LIHC cis rs75908454 0.661 rs79884685 chr6:169800884 G/A cg19338460 chr6:170058176 WDR27 -0.83 -7.52 -0.38 4.91e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs9467711 0.606 rs9379900 chr6:26603811 A/C cg09904177 chr6:26538194 HMGN4 -0.53 -5.72 -0.3 2.37e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs1580019 0.563 rs4723169 chr7:32567577 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.13 25.37 0.81 1.29e-80 Cognitive ability; LIHC cis rs870825 0.616 rs7681824 chr4:185617525 A/G cg04058563 chr4:185651563 MLF1IP 0.77 7.67 0.38 1.81e-13 Blood protein levels; LIHC cis rs1865760 0.566 rs9366634 chr6:26072396 C/G cg18357526 chr6:26021779 HIST1H4A 0.48 7.16 0.36 4.92e-12 Height; LIHC cis rs6942756 0.774 rs2694574 chr7:128908963 A/G cg02491457 chr7:128862824 NA 0.67 10.9 0.51 6.18e-24 White matter hyperintensity burden; LIHC cis rs2455799 0.574 rs2470534 chr3:15701054 C/G cg12698662 chr3:15914712 MIR563 0.37 6.73 0.34 7.01e-11 Mean platelet volume; LIHC cis rs9916302 0.904 rs8068427 chr17:37511517 G/A cg07936489 chr17:37558343 FBXL20 0.81 12.96 0.57 1.6e-31 Glomerular filtration rate (creatinine); LIHC cis rs6499255 0.953 rs3811349 chr16:69791266 T/G cg15192750 chr16:69999425 NA 0.45 6.85 0.35 3.49e-11 IgE levels; LIHC cis rs7107174 1.000 rs4945274 chr11:78109260 G/A cg02023728 chr11:77925099 USP35 0.41 7.65 0.38 2.04e-13 Testicular germ cell tumor; LIHC cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs9942416 0.660 rs2307113 chr5:74998264 C/T cg19683494 chr5:74908142 NA 0.57 7.62 0.38 2.47e-13 Age-related disease endophenotypes; LIHC cis rs7208859 0.623 rs9915566 chr17:29132158 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg07424592 chr7:64974309 NA -0.76 -8.58 -0.42 3.38e-16 Diabetic kidney disease; LIHC cis rs9733 0.596 rs11586422 chr1:150679358 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs6582630 0.537 rs1851124 chr12:38516404 G/A cg26384229 chr12:38710491 ALG10B 0.7 9.97 0.47 1.01e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs992157 0.764 rs4423579 chr2:219185033 G/T cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.21 0.48 1.49e-21 Colorectal cancer; LIHC cis rs7412746 0.611 rs2256355 chr1:150811794 A/G cg18016565 chr1:150552671 MCL1 0.5 9.74 0.47 5.99e-20 Melanoma; LIHC cis rs2526882 0.542 rs714421 chr14:71359585 A/G cg15816911 chr14:71606274 NA -0.36 -5.81 -0.3 1.46e-8 Schizophrenia; LIHC cis rs1165668 0.958 rs1165674 chr12:104320597 T/C cg21863207 chr12:104234989 NT5DC3 -0.4 -6.36 -0.33 6.43e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs4906332 1.000 rs7155822 chr14:103922390 A/G cg04998671 chr14:104000505 TRMT61A -0.44 -5.93 -0.31 7.61e-9 Coronary artery disease; LIHC cis rs3749237 0.595 rs1568661 chr3:49520958 A/G cg07636037 chr3:49044803 WDR6 0.52 7.89 0.39 4.09e-14 Resting heart rate; LIHC cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg09065629 chr16:1709722 CRAMP1L 0.33 5.93 0.31 7.41e-9 Coronary artery disease; LIHC cis rs9783347 0.961 rs2061163 chr11:18322924 A/C cg15585147 chr11:18324498 HPS5 0.45 7.02 0.35 1.22e-11 Pancreatic cancer; LIHC trans rs875971 1.000 rs811880 chr7:65818646 T/C cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs7582180 0.629 rs12617779 chr2:100937707 G/A cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs2250402 0.510 rs2291619 chr15:40329033 C/T cg01081584 chr15:40268610 EIF2AK4 0.53 6.15 0.32 2.19e-9 Corneal curvature; LIHC cis rs17854409 0.881 rs68066790 chr20:61487150 T/A cg07645718 chr20:61493192 TCFL5 0.68 5.87 0.3 1.04e-8 Obesity-related traits; LIHC cis rs1707322 0.650 rs4660879 chr1:46105401 C/A cg03146154 chr1:46216737 IPP 0.57 9.96 0.47 1.13e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6748734 1.000 rs6751693 chr2:241837332 T/C cg20140201 chr2:241835670 C2orf54 -0.46 -6.15 -0.32 2.2e-9 Urinary metabolites; LIHC trans rs911555 0.755 rs7147664 chr14:103963420 G/A cg17675199 chr6:35436792 RPL10A 0.43 8.89 0.43 3.45e-17 Intelligence (multi-trait analysis); LIHC cis rs2637266 0.783 rs1660908 chr10:78494856 T/C cg18941641 chr10:78392320 NA 0.27 5.86 0.3 1.1e-8 Pulmonary function; LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg14004847 chr7:1930337 MAD1L1 -0.46 -6.88 -0.35 2.83e-11 Bipolar disorder and schizophrenia; LIHC cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg11502198 chr6:26597334 ABT1 0.62 9.84 0.47 2.74e-20 Intelligence (multi-trait analysis); LIHC cis rs9921222 0.542 rs9926968 chr16:381561 A/C cg12437481 chr16:420112 MRPL28 -0.61 -8.52 -0.42 5.04e-16 Bone mineral density (spine);Bone mineral density; LIHC cis rs6424115 0.800 rs4649123 chr1:24197696 A/G cg10978503 chr1:24200527 CNR2 0.34 8.25 0.41 3.46e-15 Immature fraction of reticulocytes; LIHC cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg06634786 chr22:41940651 POLR3H 0.73 7.56 0.38 3.68e-13 Cannabis dependence symptom count; LIHC trans rs17780086 0.529 rs7406406 chr17:30220153 T/G cg20587970 chr11:113659929 NA -0.49 -6.38 -0.33 5.88e-10 Height; LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg02290350 chr8:58132656 NA 0.49 10.56 0.5 9.22e-23 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs9328483 chr6:8521295 A/G cg23788917 chr6:8435910 SLC35B3 0.62 8.82 0.43 5.8e-17 Motion sickness; LIHC cis rs9916302 0.851 rs612209 chr17:37442713 G/C cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC cis rs4638749 0.677 rs10190865 chr2:108843624 T/C cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs8180040 0.654 rs9837343 chr3:47177388 C/T cg16586182 chr3:47516702 SCAP -0.46 -8.3 -0.41 2.38e-15 Colorectal cancer; LIHC trans rs2243480 1.000 rs1701758 chr7:65470201 T/A cg10756647 chr7:56101905 PSPH 1.11 13.6 0.59 5.63e-34 Diabetic kidney disease; LIHC cis rs10751667 0.643 rs10902237 chr11:944801 C/A cg10932868 chr11:921992 NA 0.39 7.49 0.38 5.82e-13 Alzheimer's disease (late onset); LIHC cis rs7312933 0.703 rs12371615 chr12:42563989 C/G cg01256987 chr12:42539512 GXYLT1 -0.42 -6.96 -0.35 1.74e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4268898 0.552 rs12621083 chr2:24367540 C/T cg06627628 chr2:24431161 ITSN2 0.46 6.69 0.34 8.94e-11 Asthma; LIHC cis rs2797160 1.000 rs9491471 chr6:125991715 C/T cg05901451 chr6:126070800 HEY2 -0.37 -6.18 -0.32 1.81e-9 Endometrial cancer; LIHC trans rs208520 0.874 rs208518 chr6:66948501 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.67 7.56 0.38 3.73e-13 Exhaled nitric oxide output; LIHC cis rs17102423 0.602 rs1007914 chr14:65566261 C/A cg11161011 chr14:65562177 MAX -0.52 -7.34 -0.37 1.6e-12 Obesity-related traits; LIHC cis rs17095355 0.786 rs61624875 chr10:111722489 T/C cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.85 -0.3 1.15e-8 Biliary atresia; LIHC cis rs10504229 0.906 rs2270609 chr8:58194684 G/A cg20607798 chr8:58055168 NA 0.5 5.91 0.3 8.11e-9 Developmental language disorder (linguistic errors); LIHC cis rs5167 0.506 rs7257916 chr19:45482884 T/C cg13119609 chr19:45449297 APOC2 -0.23 -6.64 -0.34 1.25e-10 Blood protein levels; LIHC cis rs7223966 1.000 rs6504182 chr17:61823672 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.36 0.37 1.38e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs8038465 0.622 rs710086 chr15:73877001 C/T cg15420318 chr15:73925796 NPTN 0.48 7.13 0.36 5.83e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs258892 0.895 rs13170247 chr5:72069684 A/G cg21869765 chr5:72125136 TNPO1 -0.39 -5.83 -0.3 1.3e-8 Small cell lung carcinoma; LIHC cis rs4631830 0.863 rs4486572 chr10:51531805 A/G cg20129853 chr10:51489980 NA -0.42 -9.23 -0.45 2.82e-18 Prostate-specific antigen levels; LIHC cis rs875971 0.862 rs12698526 chr7:65969105 T/C cg18876405 chr7:65276391 NA 0.34 6.18 0.32 1.8e-9 Aortic root size; LIHC cis rs9596863 1.000 rs9596862 chr13:54432908 A/G ch.13.53330881F chr13:54432880 NA 0.46 6.3 0.32 8.9e-10 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs11122272 0.735 rs2486734 chr1:231531392 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg06873352 chr17:61820015 STRADA 0.73 12.83 0.57 5.17e-31 Prudent dietary pattern; LIHC cis rs10911232 0.507 rs10752890 chr1:183021910 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.47 0.49 1.99e-22 Hypertriglyceridemia; LIHC cis rs4638749 0.627 rs6542753 chr2:108815852 T/A cg06795125 chr2:108905320 SULT1C2 -0.29 -5.75 -0.3 1.94e-8 Blood pressure; LIHC cis rs9309473 0.948 rs10183818 chr2:73714556 A/G cg20560298 chr2:73613845 ALMS1 -0.57 -6.54 -0.33 2.29e-10 Metabolite levels; LIHC cis rs12908161 0.959 rs34784022 chr15:85231906 T/C cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03756088 chr1:230203084 GALNT2 -0.45 -6.66 -0.34 1.11e-10 Pancreatic cancer; LIHC cis rs2737618 0.722 rs2821330 chr1:200082464 C/T cg21825944 chr1:200113062 NR5A2 0.34 5.81 0.3 1.42e-8 Uric acid levels; LIHC cis rs7772486 0.790 rs1832362 chr6:146179955 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.58 0.53 2.13e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs4563143 0.514 rs73029081 chr19:29295583 C/G cg04546413 chr19:29218101 NA 0.5 8.53 0.42 4.88e-16 Methadone dose in opioid dependence; LIHC cis rs918629 0.530 rs3777200 chr5:95234791 A/G cg10483112 chr5:95245456 ELL2 0.36 6.53 0.33 2.38e-10 IgG glycosylation; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg12419862 chr22:24373484 LOC391322 -0.66 -9.69 -0.46 8.97e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10791097 0.694 rs7106995 chr11:130758152 G/T cg12179176 chr11:130786555 SNX19 0.88 14.59 0.62 7.91e-38 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs796364 0.806 rs11691873 chr2:200966337 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.65 -7.22 -0.36 3.35e-12 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04770364 chr12:120127985 CIT 0.42 6.18 0.32 1.87e-9 Pancreatic cancer; LIHC cis rs67478160 0.643 rs2887282 chr14:104280734 A/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.29 0.55 5.28e-29 Schizophrenia; LIHC cis rs6456156 0.586 rs10946209 chr6:167480991 G/A cg07741184 chr6:167504864 NA 0.29 6.78 0.34 5.35e-11 Primary biliary cholangitis; LIHC cis rs12928939 0.911 rs12919271 chr16:71792696 C/A cg03805757 chr16:71968109 PKD1L3 -0.74 -8.81 -0.43 6.44e-17 Post bronchodilator FEV1; LIHC cis rs1577917 0.876 rs12190735 chr6:86686467 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.37 -5.97 -0.31 6.01e-9 Response to antipsychotic treatment; LIHC cis rs425535 0.619 rs4694658 chr4:74822174 A/G cg02530824 chr4:74847766 PF4 -0.39 -6.26 -0.32 1.13e-9 Blood protein levels; LIHC cis rs3741151 0.881 rs12099129 chr11:73091318 T/G cg17517138 chr11:73019481 ARHGEF17 0.86 6.18 0.32 1.8e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs6960043 0.738 rs10950549 chr7:15057829 G/A cg19272540 chr7:15055459 NA 0.26 6.99 0.35 1.48e-11 Type 2 diabetes; LIHC cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg25894440 chr7:65020034 NA -0.52 -5.78 -0.3 1.68e-8 Diabetic kidney disease; LIHC cis rs929354 0.651 rs6951298 chr7:156949149 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs7937890 1.000 rs2970334 chr11:14329355 C/T cg19336497 chr11:14380999 RRAS2 0.39 6.68 0.34 9.64e-11 Mitochondrial DNA levels; LIHC trans rs12620999 1.000 rs12620999 chr2:238036367 C/T cg15676719 chr1:167598521 RCSD1 -0.37 -6.65 -0.34 1.18e-10 Systemic lupus erythematosus; LIHC cis rs1448094 0.512 rs61930864 chr12:86246740 G/A cg02569458 chr12:86230093 RASSF9 0.47 6.33 0.32 7.76e-10 Major depressive disorder; LIHC cis rs79149102 0.579 rs12594117 chr15:75323648 C/G cg15902774 chr15:75289873 SCAMP5 0.45 6.8 0.35 4.58e-11 Lung cancer; LIHC cis rs7493 0.755 rs13228784 chr7:94960825 A/G cg17330251 chr7:94953956 PON1 -0.45 -5.98 -0.31 5.75e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs10540 1.000 rs116101630 chr11:506826 G/C cg03576123 chr11:487126 PTDSS2 -1.06 -8.0 -0.4 1.89e-14 Body mass index; LIHC cis rs9916302 0.904 rs7208274 chr17:37513796 C/T cg03013999 chr17:37608204 MED1 -0.36 -5.99 -0.31 5.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs9549328 0.800 rs9549616 chr13:113627762 T/G cg08528486 chr13:113648767 MCF2L -0.42 -6.63 -0.34 1.33e-10 Systolic blood pressure; LIHC cis rs4713118 0.621 rs4713132 chr6:28034035 A/G cg16479474 chr6:28041457 NA 0.47 6.96 0.35 1.73e-11 Parkinson's disease; LIHC cis rs2153535 0.580 rs7741403 chr6:8530578 C/T cg21535247 chr6:8435926 SLC35B3 -0.64 -8.5 -0.42 5.86e-16 Motion sickness; LIHC cis rs765787 0.530 rs28414644 chr15:45536721 G/C cg24006582 chr15:45444508 DUOX1 -0.51 -7.27 -0.37 2.45e-12 Uric acid levels; LIHC cis rs3741404 0.825 rs60452247 chr11:63981507 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.97 16.69 0.67 3.75e-46 Platelet count; LIHC cis rs7937682 0.711 rs4938792 chr11:111420936 T/C cg09085632 chr11:111637200 PPP2R1B 0.74 9.01 0.44 1.43e-17 Primary sclerosing cholangitis; LIHC trans rs75804782 0.641 rs72985387 chr2:239336589 G/A cg01134436 chr17:81009848 B3GNTL1 0.8 6.66 0.34 1.11e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs1005277 0.522 rs11011343 chr10:38002698 A/G cg00409905 chr10:38381863 ZNF37A -0.54 -9.47 -0.46 4.86e-19 Extrinsic epigenetic age acceleration; LIHC cis rs7903847 0.642 rs2297667 chr10:99145492 A/T cg08345082 chr10:99160200 RRP12 -0.39 -6.76 -0.34 5.96e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg11764359 chr7:65958608 NA 0.69 9.33 0.45 1.37e-18 Aortic root size; LIHC cis rs8044995 0.563 rs56899435 chr16:68395675 G/A cg09835421 chr16:68378352 PRMT7 -0.81 -9.4 -0.45 8.11e-19 Schizophrenia; LIHC cis rs3812111 0.692 rs7739896 chr6:116488906 A/G cg08036074 chr6:116424633 NT5DC1 -0.46 -7.73 -0.39 1.17e-13 Age-related macular degeneration; LIHC cis rs6582630 0.574 rs12146797 chr12:38436499 T/C cg26384229 chr12:38710491 ALG10B 0.61 8.48 0.42 6.79e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs12479064 0.724 rs4851203 chr2:99986932 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.68 -8.43 -0.41 1e-15 Chronic sinus infection; LIHC trans rs1814175 0.566 rs1811673 chr11:49602134 A/G cg03929089 chr4:120376271 NA -0.69 -10.17 -0.48 2.16e-21 Height; LIHC cis rs1865721 0.804 rs1319789 chr18:73161157 C/A cg26385618 chr18:73139727 C18orf62 -0.29 -7.14 -0.36 5.77e-12 Intelligence; LIHC cis rs35306767 0.714 rs7072554 chr10:1090988 C/T cg26597838 chr10:835615 NA 0.54 6.16 0.32 1.99e-9 Eosinophil percentage of granulocytes; LIHC cis rs2635047 1.000 rs2635049 chr18:44687303 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.45 -6.02 -0.31 4.39e-9 Educational attainment; LIHC trans rs7618501 0.699 rs6446187 chr3:49907111 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.6 9.35 0.45 1.13e-18 Intelligence (multi-trait analysis); LIHC cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg09222892 chr1:25734099 RHCE -0.45 -8.1 -0.4 1.01e-14 Plateletcrit;Mean corpuscular volume; LIHC cis rs780096 0.545 rs6716894 chr2:27583273 A/G cg05484376 chr2:27715224 FNDC4 0.4 6.83 0.35 3.85e-11 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26097504 chr15:40857435 C15orf57 0.51 7.14 0.36 5.73e-12 Pancreatic cancer; LIHC cis rs60871478 1.000 rs34761279 chr7:794471 A/G cg04347379 chr7:794485 HEATR2 -0.4 -5.71 -0.3 2.4e-8 Cerebrospinal P-tau181p levels; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg24915371 chr2:232646458 PDE6D -0.38 -6.04 -0.31 4.08e-9 Body mass index; LIHC cis rs1865760 0.964 rs9295677 chr6:25933712 T/C cg17691542 chr6:26056736 HIST1H1C 0.42 6.17 0.32 1.98e-9 Height; LIHC cis rs6701037 0.625 rs34270511 chr1:175128543 C/T cg00958927 chr1:175162553 KIAA0040 -0.4 -6.55 -0.33 2.08e-10 Alcohol dependence; LIHC cis rs6977660 1.000 rs714239 chr7:19803944 C/T cg07541023 chr7:19748670 TWISTNB 0.39 6.07 0.31 3.31e-9 Thyroid stimulating hormone; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24415082 chr16:74700811 RFWD3 0.49 7.03 0.36 1.14e-11 Pancreatic cancer; LIHC cis rs4148883 0.675 rs34511427 chr4:100105405 G/T cg12011299 chr4:100065546 ADH4 0.36 7.08 0.36 8.12e-12 Alcohol dependence; LIHC cis rs763121 0.925 rs17032 chr22:39130843 C/G cg06022373 chr22:39101656 GTPBP1 0.67 13.31 0.58 7.08e-33 Menopause (age at onset); LIHC trans rs11088226 0.681 rs1015048 chr21:33949306 T/C cg09050820 chr6:167586206 TCP10L2 0.89 15.24 0.64 2.19e-40 Gastritis; LIHC cis rs9916302 0.706 rs4332770 chr17:37704712 T/C cg07936489 chr17:37558343 FBXL20 -0.84 -12.01 -0.54 5.64e-28 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs6089584 1.000 rs3787425 chr20:60559256 C/T cg12751644 chr20:60527061 NA -0.37 -6.09 -0.31 3.12e-9 Body mass index; LIHC cis rs910316 0.664 rs2098252 chr14:75492732 T/C cg08847533 chr14:75593920 NEK9 0.89 18.09 0.7 8.88e-52 Height; LIHC cis rs7131987 0.650 rs7973786 chr12:29462744 C/T cg16970926 chr12:29381810 FAR2 0.28 5.94 0.31 7.19e-9 QT interval; LIHC cis rs6430585 0.793 rs11684545 chr2:136539122 G/T cg15123519 chr2:136567270 LCT 0.44 8.77 0.43 8.82e-17 Corneal structure; LIHC cis rs9733 0.519 rs1336900 chr1:150679033 C/T cg15448220 chr1:150897856 SETDB1 0.39 6.26 0.32 1.18e-9 Tonsillectomy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20506460 chr20:43150682 SERINC3 0.42 6.2 0.32 1.63e-9 Pancreatic cancer; LIHC cis rs611744 0.631 rs627392 chr8:109254677 C/T cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs7552404 0.960 rs61797339 chr1:76189946 G/T cg22875332 chr1:76189707 ACADM 0.48 7.07 0.36 9.02e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs12701220 0.817 rs7798459 chr7:1087965 C/T cg00990874 chr7:1149470 C7orf50 -0.62 -9.08 -0.44 8.97e-18 Bronchopulmonary dysplasia; LIHC cis rs7312933 0.933 rs4534650 chr12:42444222 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.83 0.35 3.91e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.676 rs1583005 chr5:140031537 G/A cg19875535 chr5:140030758 IK -0.43 -6.99 -0.35 1.41e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.704 rs7359501 chr17:56641200 C/T cg25039879 chr17:56429692 SUPT4H1 0.43 6.03 0.31 4.37e-9 Cognitive test performance; LIHC cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.16 -0.36 5.11e-12 Diabetic kidney disease; LIHC cis rs17345786 0.667 rs7622940 chr3:101133155 T/C cg11279151 chr3:101281821 RG9MTD1 -0.49 -7.23 -0.36 3.18e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs67460515 0.563 rs6794882 chr3:160851849 G/A cg17135325 chr3:160939158 NMD3 0.55 7.8 0.39 7.67e-14 Parkinson's disease; LIHC cis rs5769765 0.671 rs138844 chr22:50184484 T/G cg02269571 chr22:50332266 NA -0.56 -7.74 -0.39 1.12e-13 Schizophrenia; LIHC cis rs1707322 1.000 rs10890382 chr1:46469674 A/G cg06784218 chr1:46089804 CCDC17 0.38 6.75 0.34 6.53e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg07424592 chr7:64974309 NA 0.77 8.9 0.43 3.31e-17 Diabetic kidney disease; LIHC cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.71 0.3 2.46e-8 Electroencephalogram traits; LIHC cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg00684032 chr4:1343700 KIAA1530 0.51 7.35 0.37 1.5e-12 Obesity-related traits; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg16358155 chr3:195490169 MUC4 -0.45 -6.8 -0.35 4.6e-11 Lung disease severity in cystic fibrosis; LIHC cis rs4555082 0.957 rs2816609 chr14:105720803 A/C cg10792982 chr14:105748885 BRF1 0.46 6.29 0.32 9.86e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.55 -7.84 -0.39 5.95e-14 Lymphocyte counts; LIHC cis rs739401 0.572 rs410820 chr11:3080102 G/A cg20651018 chr11:3035856 CARS -0.37 -6.12 -0.31 2.5e-9 Longevity; LIHC cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.51 0.33 2.68e-10 Bipolar disorder; LIHC cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg14391382 chr7:866102 UNC84A 0.38 5.71 0.3 2.44e-8 Perceived unattractiveness to mosquitoes; LIHC cis rs12477438 0.798 rs6542848 chr2:99573732 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.76 -11.19 -0.52 5.65e-25 Chronic sinus infection; LIHC cis rs3820068 0.705 rs4646075 chr1:15827461 T/C cg17385448 chr1:15911702 AGMAT 0.37 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs11122272 0.735 rs2808597 chr1:231532351 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.36 0.45 1.08e-18 Hemoglobin concentration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23645831 chr1:15944060 DDI2 -0.43 -6.09 -0.31 3e-9 Longevity; LIHC cis rs4925386 0.959 rs6121989 chr20:60916713 A/T cg03945807 chr20:60948434 NA -0.36 -6.44 -0.33 3.97e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs16944613 0.588 rs12438183 chr15:91139244 T/C cg26821196 chr15:91095069 CRTC3 0.43 7.2 0.36 3.91e-12 Colorectal cancer; LIHC trans rs1814175 0.647 rs1404157 chr11:49917301 G/C cg03929089 chr4:120376271 NA -0.58 -9.68 -0.46 9.68e-20 Height; LIHC cis rs8062405 1.000 rs4788099 chr16:28855727 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2836950 0.565 rs7279497 chr21:40531306 A/G cg06238570 chr21:40685208 BRWD1 0.39 6.38 0.33 5.67e-10 Menarche (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18890249 chr10:51361773 LOC728407;PARG -0.39 -6.57 -0.33 1.83e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6545883 0.931 rs7557230 chr2:61736652 A/T cg15711740 chr2:61764176 XPO1 -0.42 -6.04 -0.31 4.11e-9 Tuberculosis; LIHC cis rs1816752 0.712 rs6490932 chr13:25017451 A/G cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.81e-10 Obesity-related traits; LIHC cis rs9916302 0.706 rs1054488 chr17:37687968 A/G cg07936489 chr17:37558343 FBXL20 -0.84 -11.98 -0.54 7.41e-28 Glomerular filtration rate (creatinine); LIHC cis rs2153535 0.580 rs9328488 chr6:8529411 G/C cg21535247 chr6:8435926 SLC35B3 0.65 8.63 0.42 2.43e-16 Motion sickness; LIHC cis rs950169 0.580 rs1061737 chr15:85183790 G/C cg12863693 chr15:85201151 NMB 0.49 6.78 0.34 5.41e-11 Schizophrenia; LIHC cis rs1691799 0.867 rs1168342 chr12:66758734 A/T cg16791601 chr12:66731901 HELB -0.54 -13.08 -0.58 5.56e-32 White blood cell count (basophil); LIHC cis rs2580764 0.566 rs2968793 chr2:55285024 C/T cg09592903 chr2:55203963 RTN4 0.64 11.7 0.53 7.69e-27 Mean platelet volume; LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs8067354 0.574 rs1292050 chr17:57965169 T/C cg13753209 chr17:57696993 CLTC 0.7 10.33 0.49 5.98e-22 Hemoglobin concentration; LIHC cis rs10089 1.000 rs4836363 chr5:127462737 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.25e-11 Ileal carcinoids; LIHC trans rs11148252 0.875 rs9526913 chr13:52975837 T/C cg18335740 chr13:41363409 SLC25A15 0.34 6.08 0.31 3.19e-9 Lewy body disease; LIHC cis rs4474465 0.831 rs12287010 chr11:78161452 A/T cg02023728 chr11:77925099 USP35 -0.35 -6.18 -0.32 1.83e-9 Alzheimer's disease (survival time); LIHC trans rs60843830 1.000 rs60843830 chr2:286756 C/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.63 8.64 0.42 2.19e-16 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs10744422 1.000 rs4759381 chr12:123348480 G/A cg07706471 chr12:123319906 HIP1R -0.62 -7.89 -0.39 4.16e-14 Schizophrenia; LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs6456156 0.565 rs12529238 chr6:167465576 G/A cg12798992 chr6:167411361 FGFR1OP 0.42 6.61 0.34 1.48e-10 Primary biliary cholangitis; LIHC cis rs3845702 0.736 rs2367990 chr2:180843126 C/T cg01881094 chr2:180872142 CWC22 -1.14 -10.24 -0.48 1.26e-21 Schizophrenia; LIHC cis rs7523273 0.597 rs2724384 chr1:207930203 G/A cg22525895 chr1:207977042 MIR29B2 0.64 7.4 0.37 1.03e-12 Schizophrenia; LIHC cis rs2832191 1.000 rs2832184 chr21:30483265 C/T cg08807101 chr21:30365312 RNF160 -0.59 -9.28 -0.45 2.02e-18 Dental caries; LIHC cis rs2737618 0.698 rs2737678 chr1:200088041 C/T cg21825944 chr1:200113062 NR5A2 -0.41 -6.66 -0.34 1.11e-10 Uric acid levels; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.99 -23.08 -0.78 1.05e-71 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 3.04e-30 Menopause (age at onset); LIHC cis rs10508774 0.733 rs3758380 chr10:33188453 A/G cg01819863 chr10:32635814 EPC1 0.64 5.82 0.3 1.38e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9394841 0.667 rs3747750 chr6:41760372 C/G cg17623882 chr6:41773611 USP49 -0.44 -5.85 -0.3 1.15e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs2836950 0.527 rs2836948 chr21:40599677 T/C cg11890956 chr21:40555474 PSMG1 -0.46 -7.37 -0.37 1.32e-12 Menarche (age at onset); LIHC cis rs9788682 0.894 rs4461039 chr15:78817447 A/T cg06917634 chr15:78832804 PSMA4 0.5 7.22 0.36 3.4e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs6748734 0.948 rs9973366 chr2:241838151 T/C cg08694578 chr2:241835147 C2orf54 -0.63 -10.06 -0.48 4.99e-21 Urinary metabolites; LIHC cis rs12702595 0.643 rs2108787 chr7:7259034 G/A cg04827551 chr7:7268805 C1GALT1 0.31 5.72 0.3 2.27e-8 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs763121 0.853 rs6001204 chr22:39100239 T/C cg14440974 chr22:39074834 NA -0.37 -6.25 -0.32 1.21e-9 Menopause (age at onset); LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs3770081 0.793 rs60719866 chr2:86284378 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.57 8.8 0.43 7.13e-17 Facial emotion recognition (sad faces); LIHC cis rs6952808 0.792 rs12536261 chr7:1953571 G/A cg04267008 chr7:1944627 MAD1L1 -0.71 -11.53 -0.53 3.21e-26 Bipolar disorder and schizophrenia; LIHC cis rs7666738 0.753 rs35146453 chr4:98902278 A/G cg05340658 chr4:99064831 C4orf37 0.65 11.81 0.54 3.25e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs35362007 0.530 rs17835086 chr14:96012465 A/G cg02940042 chr14:96000874 GLRX5;SNHG10;SCARNA13 0.74 6.33 0.32 7.53e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.817 rs8142561 chr22:50291750 T/C cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.23e-16 Schizophrenia; LIHC cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg16606324 chr3:10149918 C3orf24 0.53 5.77 0.3 1.73e-8 Alzheimer's disease; LIHC cis rs74417235 0.639 rs7443642 chr5:154053450 A/G cg08893839 chr5:154027129 NA -0.5 -6.83 -0.35 3.95e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs2806561 0.808 rs1413974 chr1:23347125 C/T cg19743168 chr1:23544995 NA -0.36 -6.64 -0.34 1.26e-10 Height; LIHC cis rs6952808 0.792 rs12536261 chr7:1953571 G/A cg21782813 chr7:2030301 MAD1L1 0.48 8.13 0.4 8.17e-15 Bipolar disorder and schizophrenia; LIHC cis rs7959452 0.640 rs4761154 chr12:69705362 A/G cg20891283 chr12:69753455 YEATS4 -0.81 -15.26 -0.64 1.89e-40 Blood protein levels; LIHC cis rs11971779 0.680 rs17613690 chr7:139088401 C/T cg07862535 chr7:139043722 LUC7L2 -0.6 -10.34 -0.49 5.72e-22 Diisocyanate-induced asthma; LIHC cis rs9381040 0.655 rs2268192 chr6:41024626 T/C cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.13 -0.31 2.41e-9 Alzheimer's disease (late onset); LIHC cis rs4746818 0.901 rs4746816 chr10:70874866 G/T cg11621586 chr10:70884670 VPS26A 0.82 11.56 0.53 2.5e-26 Left atrial antero-posterior diameter; LIHC cis rs428668 0.523 rs10060607 chr5:150679304 A/C cg14086364 chr5:150678334 SLC36A3 0.29 7.82 0.39 6.55e-14 Skin aging (microtopography measurement); LIHC cis rs3812111 0.838 rs476330 chr6:116433265 C/T cg08036074 chr6:116424633 NT5DC1 0.65 11.2 0.52 5.37e-25 Age-related macular degeneration; LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg16822855 chr3:40428330 ENTPD3 0.33 5.95 0.31 6.77e-9 Renal cell carcinoma; LIHC cis rs2412488 0.893 rs11734681 chr4:54353092 G/A cg22241045 chr4:54363911 LNX1 -0.43 -7.06 -0.36 9.37e-12 DNA methylation (variation); LIHC cis rs17685 0.753 rs7804598 chr7:75702578 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.21 -0.32 1.52e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6545883 0.929 rs2593625 chr2:61668769 C/T cg15711740 chr2:61764176 XPO1 -0.43 -6.06 -0.31 3.67e-9 Tuberculosis; LIHC cis rs1144333 1.000 rs5745354 chr1:76275178 G/A cg10523679 chr1:76189770 ACADM -0.43 -6.47 -0.33 3.31e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs8141529 0.748 rs1318025 chr22:29283757 C/T cg02153584 chr22:29168773 CCDC117 0.52 8.12 0.4 8.73e-15 Lymphocyte counts; LIHC trans rs9641123 0.639 rs2528537 chr7:93247388 A/T cg09745688 chr16:2908918 PRSS22 -0.36 -6.34 -0.32 7.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs6831352 0.918 rs13133647 chr4:100058727 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs1355223 0.902 rs1539250 chr11:34742775 C/T cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.58 -0.34 1.81e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs8180040 0.966 rs62260711 chr3:47564491 G/C cg16586182 chr3:47516702 SCAP 0.44 7.49 0.38 5.98e-13 Colorectal cancer; LIHC cis rs17253792 0.822 rs75509578 chr14:56133493 G/A cg01858014 chr14:56050164 KTN1 -0.7 -8.09 -0.4 1.06e-14 Putamen volume; LIHC cis rs1865721 1.000 rs17284077 chr18:73204128 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.56 -0.38 3.8e-13 Intelligence; LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg07424592 chr7:64974309 NA 0.8 9.21 0.45 3.38e-18 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg24209194 chr3:40518798 ZNF619 0.54 7.82 0.39 6.75e-14 Renal cell carcinoma; LIHC trans rs7504990 0.691 rs76571698 chr18:50366942 C/T cg08535148 chr4:26321143 RBPJ 0.54 6.66 0.34 1.06e-10 Gallbladder cancer; LIHC cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg25894440 chr7:65020034 NA 0.52 6.05 0.31 3.73e-9 Diabetic kidney disease; LIHC cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.12 -0.44 6.77e-18 Bipolar disorder; LIHC cis rs600806 0.778 rs11101960 chr1:110008778 C/T cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.78 -0.39 8.73e-14 Intelligence (multi-trait analysis); LIHC cis rs372883 0.563 rs1153293 chr21:30691325 C/T cg08807101 chr21:30365312 RNF160 0.53 6.36 0.33 6.35e-10 Pancreatic cancer; LIHC cis rs2191566 0.922 rs7245749 chr19:44513932 G/A cg20607764 chr19:44506953 ZNF230 -0.41 -6.69 -0.34 9.11e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs11098499 1.000 rs28374891 chr4:120183550 G/A cg09307838 chr4:120376055 NA 0.74 10.94 0.51 4.24e-24 Corneal astigmatism; LIHC cis rs12477438 0.520 rs7572660 chr2:99788582 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.66 0.65 4.89e-42 Chronic sinus infection; LIHC cis rs1997103 0.911 rs17777 chr7:55380765 T/C cg17469321 chr7:55412551 NA 0.49 7.24 0.36 2.96e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7633770 0.841 rs11709936 chr3:46680483 C/G cg11219411 chr3:46661640 NA 0.54 9.7 0.46 8.28e-20 Coronary artery disease; LIHC cis rs244293 0.795 rs11079151 chr17:53095366 G/A cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.51 0.38 5.12e-13 Menarche (age at onset); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg01296682 chr20:5891730 CHGB 0.4 6.37 0.33 6.26e-10 Morning vs. evening chronotype; LIHC cis rs3859192 0.599 rs2227321 chr17:38171294 G/C cg17344932 chr17:38183730 MED24;SNORD124 0.8 16.2 0.66 3.29e-44 White blood cell count; LIHC cis rs5769765 1.000 rs5769765 chr22:50271176 G/A cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs35306767 0.903 rs17159970 chr10:935601 T/C cg26597838 chr10:835615 NA 1.14 13.45 0.59 2.16e-33 Eosinophil percentage of granulocytes; LIHC cis rs7131987 0.903 rs10843373 chr12:29420608 A/T cg00204748 chr12:29376779 FAR2 0.43 8.05 0.4 1.36e-14 QT interval; LIHC cis rs17401966 1.000 rs12136376 chr1:10296452 C/T cg19773385 chr1:10388646 KIF1B -0.47 -8.19 -0.41 5.14e-15 Hepatocellular carcinoma; LIHC cis rs950776 0.518 rs2869544 chr15:78839400 G/A cg06917634 chr15:78832804 PSMA4 -0.89 -13.53 -0.59 1.02e-33 Sudden cardiac arrest; LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg08677398 chr8:58056175 NA -0.42 -5.74 -0.3 2.09e-8 Developmental language disorder (linguistic errors); LIHC cis rs1008375 1.000 rs1558377 chr4:17650758 A/G cg15017067 chr4:17643749 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11190604 1.000 rs79831012 chr10:102237059 T/C cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1784581 0.802 rs2156747 chr6:162430000 C/G cg17173639 chr6:162384350 PARK2 -0.64 -13.05 -0.58 7.41e-32 Itch intensity from mosquito bite; LIHC cis rs6952808 0.792 rs2056481 chr7:1955435 A/G cg20295408 chr7:1910781 MAD1L1 -0.5 -7.16 -0.36 4.9e-12 Bipolar disorder and schizophrenia; LIHC trans rs1814175 0.817 rs4881627 chr11:49953955 C/A cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs11148252 0.574 rs9536247 chr13:53279542 T/C cg12458913 chr13:53173898 NA 0.5 8.04 0.4 1.5e-14 Lewy body disease; LIHC cis rs9467773 0.526 rs12199613 chr6:26367218 C/T cg14345882 chr6:26364793 BTN3A2 0.34 5.74 0.3 2.04e-8 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21530174 chr5:151031796 NA 0.5 6.91 0.35 2.38e-11 Lung function (FEV1/FVC); LIHC cis rs8017423 0.647 rs4904674 chr14:90817412 G/A cg14092571 chr14:90743983 NA 0.42 5.8 0.3 1.54e-8 Mortality in heart failure; LIHC cis rs1371867 0.555 rs2861348 chr8:101285074 A/G cg06636551 chr8:101224915 SPAG1 -0.49 -8.9 -0.43 3.27e-17 Atrioventricular conduction; LIHC cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg02290350 chr8:58132656 NA 0.5 9.61 0.46 1.6e-19 Developmental language disorder (linguistic errors); LIHC cis rs6570726 0.935 rs397418 chr6:145842362 C/T cg23711669 chr6:146136114 FBXO30 0.56 9.93 0.47 1.34e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs4742903 0.935 rs10991166 chr9:106974096 T/C cg14250997 chr9:106856677 SMC2 0.36 6.1 0.31 2.85e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs9517302 0.615 rs3752974 chr13:99097827 T/C cg22223119 chr13:99095684 FARP1 -0.59 -8.5 -0.42 6e-16 Obesity-related traits; LIHC cis rs10876993 0.890 rs12302351 chr12:58062590 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.57 -0.33 1.86e-10 Celiac disease or Rheumatoid arthritis; LIHC trans rs11098499 0.954 rs3890049 chr4:120326283 T/A cg25214090 chr10:38739885 LOC399744 0.6 9.81 0.47 3.5e-20 Corneal astigmatism; LIHC cis rs1008375 1.000 rs11724495 chr4:17621310 G/A cg16339924 chr4:17578868 LAP3 0.45 6.3 0.32 9.03e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg08219700 chr8:58056026 NA 0.53 6.36 0.33 6.29e-10 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.929 rs6500603 chr16:4497537 G/C cg08645402 chr16:4508243 NA 0.4 7.49 0.38 6.05e-13 Schizophrenia; LIHC cis rs6912958 0.781 rs2273129 chr6:88182439 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.1 -0.36 7.08e-12 Monocyte percentage of white cells; LIHC trans rs4710654 0.516 rs34124069 chr6:68508308 T/C cg00011122 chr16:11439027 C16orf75 -0.4 -6.09 -0.31 3.01e-9 Response to amphetamines; LIHC cis rs10744422 0.843 rs3896870 chr12:123333611 T/C cg22842854 chr12:123319900 HIP1R -0.74 -9.71 -0.46 7.68e-20 Schizophrenia; LIHC cis rs7589728 0.516 rs79815126 chr2:88488270 G/A cg14558114 chr2:88469736 THNSL2 0.64 5.85 0.3 1.12e-8 Plasma clusterin levels; LIHC cis rs61990749 0.597 rs4903643 chr14:78254791 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.0 0.48 8.3e-21 Fibroblast growth factor basic levels; LIHC cis rs17685 0.753 rs2302435 chr7:75676987 G/A cg04592579 chr7:75616294 TMEM120A -0.39 -6.68 -0.34 9.71e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6684514 0.922 rs11264475 chr1:156306918 G/A cg16558208 chr1:156270281 VHLL 0.54 10.31 0.49 7.15e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs35110281 0.626 rs162388 chr21:44936032 G/A cg21573476 chr21:45109991 RRP1B -0.42 -7.77 -0.39 9.38e-14 Mean corpuscular volume; LIHC cis rs875971 0.522 rs781144 chr7:65440344 C/G cg11764359 chr7:65958608 NA 0.7 9.4 0.45 7.79e-19 Aortic root size; LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs4975616 0.869 rs31484 chr5:1337906 A/T cg06550200 chr5:1325588 CLPTM1L -0.69 -10.81 -0.5 1.21e-23 Lung cancer; LIHC cis rs11105298 0.891 rs11105299 chr12:89877943 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.55 -0.38 3.92e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs11098499 0.909 rs79704848 chr4:120309351 T/A cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.08 11.64 0.53 1.34e-26 Platelet count; LIHC cis rs10791323 0.569 rs2282601 chr11:133712594 C/G cg06766960 chr11:133703094 NA -0.65 -10.93 -0.51 4.88e-24 Childhood ear infection; LIHC cis rs7107174 1.000 rs4492844 chr11:78026516 A/G cg02023728 chr11:77925099 USP35 0.52 9.62 0.46 1.49e-19 Testicular germ cell tumor; LIHC cis rs67981189 0.593 rs2810101 chr14:71429827 G/C cg15816911 chr14:71606274 NA -0.4 -6.45 -0.33 3.85e-10 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17875356 chr3:114807036 ZBTB20 0.26 6.38 0.33 5.84e-10 Cognitive function; LIHC cis rs3617 0.652 rs60332615 chr3:52867595 C/A cg11645453 chr3:52864694 ITIH4 -0.22 -5.95 -0.31 6.65e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9896052 0.614 rs34042490 chr17:73452956 T/C cg25649188 chr17:73499917 CASKIN2 0.43 6.7 0.34 8.81e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs1371867 0.875 rs1788187 chr8:101336099 A/G cg06636551 chr8:101224915 SPAG1 -0.47 -8.72 -0.43 1.26e-16 Atrioventricular conduction; LIHC cis rs7264396 1.000 rs224430 chr20:34153341 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.85 -0.35 3.44e-11 Total cholesterol levels; LIHC cis rs4665809 0.887 rs28699126 chr2:26357294 C/T cg04944784 chr2:26401820 FAM59B -0.64 -8.18 -0.4 5.66e-15 Gut microbiome composition (summer); LIHC cis rs477692 0.789 rs507900 chr10:131398144 A/G cg05714579 chr10:131428358 MGMT -0.46 -7.61 -0.38 2.61e-13 Response to temozolomide; LIHC cis rs7103648 0.838 rs2293576 chr11:47434986 A/G cg20307385 chr11:47447363 PSMC3 -0.99 -15.67 -0.65 4.36e-42 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs2029362 0.611 rs2030324 chr11:27726915 A/G cg18117895 chr11:27722066 BDNF -0.39 -5.89 -0.3 9.49e-9 Total body bone mineral density; LIHC cis rs847649 0.732 rs6465876 chr7:102497569 G/T cg18108683 chr7:102477205 FBXL13 -0.5 -7.8 -0.39 7.37e-14 Morning vs. evening chronotype; LIHC cis rs1577917 0.771 rs2842613 chr6:86305702 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.41 7.1 0.36 7.09e-12 Response to antipsychotic treatment; LIHC cis rs7116495 0.609 rs10736780 chr11:71650241 T/C cg10381502 chr11:71823885 C11orf51 -1.0 -8.24 -0.41 3.84e-15 Severe influenza A (H1N1) infection; LIHC cis rs2439831 0.850 rs8042868 chr15:43939642 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.57 6.89 0.35 2.69e-11 Lung cancer in ever smokers; LIHC cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg03452623 chr4:187889614 NA -0.32 -8.23 -0.41 3.86e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.46 0.37 7.3e-13 Obesity-related traits; LIHC cis rs853679 0.517 rs9380057 chr6:28104634 G/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg06656553 chr16:89960601 TCF25 -0.49 -6.01 -0.31 4.66e-9 Skin colour saturation; LIHC cis rs9649213 0.593 rs3779194 chr7:98010277 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.84 -0.3 1.19e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs17106184 1.000 rs72898980 chr1:50986747 A/G cg07174182 chr1:51127561 FAF1 -0.7 -7.11 -0.36 6.97e-12 Type 2 diabetes; LIHC cis rs4665809 0.941 rs41285975 chr2:26351144 T/C cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs4665809 1.000 rs11126375 chr2:26344787 G/A cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs7872515 0.887 rs7856177 chr9:94839342 A/G cg01248375 chr9:94877805 SPTLC1 0.56 8.23 0.41 4.04e-15 Bipolar disorder and schizophrenia; LIHC cis rs1577917 1.000 rs10455449 chr6:86592226 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.85 -0.51 8.78e-24 Response to antipsychotic treatment; LIHC cis rs240764 0.621 rs11155636 chr6:101201243 C/T cg09795085 chr6:101329169 ASCC3 -0.56 -8.06 -0.4 1.34e-14 Neuroticism; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg07677032 chr17:61819896 STRADA 0.42 5.98 0.31 5.66e-9 Prudent dietary pattern; LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg26338869 chr17:61819248 STRADA 0.5 6.5 0.33 2.87e-10 Height; LIHC cis rs7772486 0.720 rs6570713 chr6:146075085 G/A cg23711669 chr6:146136114 FBXO30 -0.73 -13.45 -0.59 2.16e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs2576037 0.583 rs9947131 chr18:44534769 G/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.87 -0.3 1.02e-8 Personality dimensions; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg05673432 chr3:15919505 NA 0.43 6.09 0.31 3.1e-9 Alopecia areata; LIHC cis rs2439831 1.000 rs689647 chr15:43762196 C/T cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.32e-9 Lung cancer in ever smokers; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg05484376 chr2:27715224 FNDC4 0.38 6.4 0.33 5.02e-10 Total body bone mineral density; LIHC trans rs983392 0.709 rs11826180 chr11:59991333 T/C cg17275991 chr19:58003312 ZNF419 0.42 6.06 0.31 3.61e-9 Alzheimer's disease (late onset); LIHC trans rs1814175 0.817 rs7947526 chr11:49983654 T/C cg18944383 chr4:111397179 ENPEP 0.28 7.18 0.36 4.32e-12 Height; LIHC cis rs9649465 0.967 rs1005567 chr7:123305836 A/T cg03229431 chr7:123269106 ASB15 0.37 8.05 0.4 1.37e-14 Migraine; LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs34375054 0.573 rs34579346 chr12:125658174 T/C cg25124228 chr12:125621409 AACS -0.43 -6.63 -0.34 1.29e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs62229266 0.587 rs62229264 chr21:37452213 G/A cg12218747 chr21:37451666 NA -0.44 -7.14 -0.36 5.77e-12 Mitral valve prolapse; LIHC cis rs919433 0.680 rs7582536 chr2:198436103 C/T cg03934865 chr2:198174659 NA -0.54 -8.31 -0.41 2.25e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs13223928 0.592 rs4722439 chr7:3155858 C/T cg19214707 chr7:3157722 NA 0.44 8.39 0.41 1.27e-15 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs748404 0.588 rs506120 chr15:43802024 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.14 0.4 7.27e-15 Lung cancer; LIHC cis rs73591976 0.539 rs12446198 chr16:68125972 G/A cg09835421 chr16:68378352 PRMT7 -0.53 -6.0 -0.31 5.12e-9 HDL cholesterol; LIHC cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg11764359 chr7:65958608 NA 0.59 6.08 0.31 3.26e-9 Diabetic kidney disease; LIHC cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg12311346 chr5:56204834 C5orf35 -0.57 -7.48 -0.37 6.39e-13 Initial pursuit acceleration; LIHC cis rs782590 0.837 rs782573 chr2:55912961 T/C cg03859395 chr2:55845619 SMEK2 0.81 13.83 0.6 7.61e-35 Metabolic syndrome; LIHC cis rs9916302 0.904 rs13341996 chr17:37536862 C/T cg07936489 chr17:37558343 FBXL20 0.85 13.68 0.59 2.7200000000000002e-34 Glomerular filtration rate (creatinine); LIHC cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.51 0.33 2.73e-10 Bipolar disorder; LIHC cis rs1144333 0.850 rs1144341 chr1:76282659 T/G cg03433033 chr1:76189801 ACADM -0.56 -8.51 -0.42 5.6e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs13190036 0.892 rs71601339 chr5:176544496 A/G cg06532880 chr5:176731545 PRELID1;RAB24 0.45 5.85 0.3 1.16e-8 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs4423214 0.650 rs7940244 chr11:71221574 C/T cg05163923 chr11:71159392 DHCR7 -0.72 -10.7 -0.5 2.98e-23 Vitamin D levels; LIHC cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2370759 1.000 rs76998371 chr10:32631785 A/G cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs35306767 0.903 rs12769873 chr10:936526 G/T cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs72627123 0.867 rs57685514 chr14:74487592 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.56 0.46 2.44e-19 Morning vs. evening chronotype; LIHC cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.41 -5.73 -0.3 2.23e-8 Colorectal cancer; LIHC cis rs1062177 1.000 rs2964578 chr5:151147198 T/A cg00977110 chr5:151150581 G3BP1 0.56 7.04 0.36 1.08e-11 Preschool internalizing problems; LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg00035636 chr13:21900591 NA 0.39 6.47 0.33 3.47e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs243505 0.595 rs10233740 chr7:148567263 C/T cg09806900 chr7:148480153 CUL1 0.44 6.29 0.32 9.47e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12824058 0.831 rs11608407 chr12:130805869 G/A cg24838063 chr12:130822603 PIWIL1 0.67 9.28 0.45 2.01e-18 Menopause (age at onset); LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg04013166 chr16:89971882 TCF25 0.6 7.92 0.39 3.27e-14 Skin colour saturation; LIHC cis rs16858210 0.837 rs11716104 chr3:183581999 G/C cg25686905 chr3:183603175 PARL -0.5 -9.57 -0.46 2.17e-19 Menopause (age at onset); LIHC cis rs412000 0.554 rs2680700 chr17:56440542 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.47 6.47 0.33 3.34e-10 Primary tooth development (time to first tooth eruption); LIHC cis rs4713118 0.868 rs10484401 chr6:27746590 A/T cg20933634 chr6:27740509 NA -0.47 -6.16 -0.32 2.09e-9 Parkinson's disease; LIHC cis rs4820539 0.934 rs3788348 chr22:23467946 G/C cg21100191 chr22:23484243 RTDR1 0.91 16.53 0.67 1.58e-45 Bone mineral density; LIHC cis rs8180040 0.654 rs1466740 chr3:47245883 C/T cg27129171 chr3:47204927 SETD2 -0.56 -9.26 -0.45 2.26e-18 Colorectal cancer; LIHC cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg16926213 chr1:1841314 NA 0.31 5.72 0.3 2.3e-8 Body mass index; LIHC cis rs12600856 1 rs12600856 chr17:38163295 T/C cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.14 -0.44 5.58e-18 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs57502260 0.651 rs3781586 chr11:68199393 C/A cg20283391 chr11:68216788 NA -0.51 -6.37 -0.33 6.18e-10 Total body bone mineral density (age 45-60); LIHC cis rs2070433 1.000 rs2839302 chr21:47952364 G/A cg12379764 chr21:47803548 PCNT 0.64 9.24 0.45 2.64e-18 Lymphocyte counts; LIHC cis rs7552404 0.855 rs385897 chr1:76106962 T/C cg22875332 chr1:76189707 ACADM -0.49 -7.3 -0.37 2.08e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9303401 1.000 rs6503877 chr17:56841948 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 7.28 0.37 2.29e-12 Cognitive test performance; LIHC cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg13047869 chr3:10149882 C3orf24 0.54 6.41 0.33 4.82e-10 Alzheimer's disease; LIHC cis rs2274273 1.000 rs15870 chr14:55619311 A/G cg01864836 chr14:55583639 NA -0.36 -6.12 -0.31 2.62e-9 Protein biomarker; LIHC cis rs7762018 1.000 rs6904601 chr6:170131905 T/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.56 6.83 0.35 3.81e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6964587 0.692 rs10227225 chr7:91571074 A/G cg17063962 chr7:91808500 NA -0.64 -11.26 -0.52 3.18e-25 Breast cancer; LIHC cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg07424592 chr7:64974309 NA 0.73 8.54 0.42 4.46e-16 Diabetic kidney disease; LIHC cis rs11628318 0.614 rs8010455 chr14:103164681 A/G cg01864069 chr14:103024347 NA 0.46 7.16 0.36 5.09e-12 Platelet count; LIHC cis rs35306767 0.855 rs11253499 chr10:944090 A/C cg26597838 chr10:835615 NA 1.13 13.51 0.59 1.31e-33 Eosinophil percentage of granulocytes; LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.88 0.3 9.7e-9 Tonsillectomy; LIHC cis rs2629540 0.889 rs4962696 chr10:126445630 A/G cg08799069 chr10:126477246 METTL10 -0.53 -8.52 -0.42 5.34e-16 Cocaine dependence; LIHC cis rs8072100 0.840 rs9893901 chr17:45506682 T/G cg08085267 chr17:45401833 C17orf57 -0.54 -8.18 -0.4 5.69e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7959452 0.562 rs11177630 chr12:69767963 G/C cg14784868 chr12:69753453 YEATS4 0.95 20.47 0.74 2.21e-61 Blood protein levels; LIHC cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg11890956 chr21:40555474 PSMG1 -0.5 -8.2 -0.41 4.88e-15 Cognitive function; LIHC cis rs6570726 0.689 rs411785 chr6:145888398 G/A cg13319975 chr6:146136371 FBXO30 -0.42 -6.74 -0.34 6.69e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2455799 0.553 rs2262664 chr3:15768097 A/T cg12698662 chr3:15914712 MIR563 -0.39 -7.16 -0.36 5.03e-12 Mean platelet volume; LIHC cis rs2354432 0.556 rs72710311 chr1:146698256 A/G cg25205988 chr1:146714368 CHD1L -0.9 -10.7 -0.5 3.07e-23 Mitochondrial DNA levels; LIHC cis rs6952808 0.929 rs1801368 chr7:1976457 C/T cg04267008 chr7:1944627 MAD1L1 -0.65 -10.34 -0.49 5.34e-22 Bipolar disorder and schizophrenia; LIHC cis rs2522056 1.000 rs2706393 chr5:131796067 G/A cg24060327 chr5:131705240 SLC22A5 0.53 7.16 0.36 4.87e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs1267303 0.675 rs1745370 chr1:46982863 C/G cg25110126 chr1:46999211 NA -0.51 -6.61 -0.34 1.49e-10 Monobrow; LIHC cis rs12048904 0.647 rs7528268 chr1:101329295 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 11.47 0.53 5.4e-26 Multiple sclerosis; LIHC cis rs59901009 0.911 rs61192802 chr11:10200742 A/G cg01453529 chr11:10209919 SBF2 -0.33 -6.52 -0.33 2.59e-10 Hematocrit;Hemoglobin concentration; LIHC cis rs16828019 0.777 rs12748235 chr1:41466221 G/A cg03962019 chr1:41807865 NA 0.53 7.01 0.35 1.26e-11 Intelligence (multi-trait analysis); LIHC cis rs4563143 0.514 rs73030738 chr19:29312328 G/A cg04546413 chr19:29218101 NA 0.49 8.48 0.42 6.84e-16 Methadone dose in opioid dependence; LIHC cis rs7044106 0.762 rs1158554 chr9:123400898 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.89 0.51 6.71e-24 Hip circumference adjusted for BMI; LIHC cis rs13191362 1.000 rs35449999 chr6:163023465 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.65 5.77 0.3 1.77e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7072216 0.763 rs6584205 chr10:100173806 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs1059312 1.000 rs7302634 chr12:129279931 C/T cg09035930 chr12:129282057 SLC15A4 0.7 13.25 0.58 1.26e-32 Systemic lupus erythematosus; LIHC cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg09417038 chr21:47716443 C21orf57 -0.5 -7.34 -0.37 1.56e-12 Testicular germ cell tumor; LIHC cis rs9399137 0.507 rs7771310 chr6:135272535 G/A cg24558204 chr6:135376177 HBS1L 0.61 10.4 0.49 3.35e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs6912958 0.559 rs242281 chr6:88048916 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.94 0.51 4.23e-24 Monocyte percentage of white cells; LIHC cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.06 10.83 0.51 1.06e-23 Platelet count; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg16103275 chr6:290800 DUSP22 0.52 7.06 0.36 9.28e-12 Menopause (age at onset); LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg14393609 chr7:65229607 NA 0.41 7.03 0.36 1.16e-11 Calcium levels; LIHC cis rs6912958 0.559 rs242280 chr6:88048714 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.32 0.37 1.74e-12 Monocyte percentage of white cells; LIHC cis rs8072100 0.840 rs12453233 chr17:45454570 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.86 -0.3 1.08e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs61677309 0.964 rs59138930 chr11:118173783 C/T cg06090739 chr11:118230722 UBE4A 0.35 6.44 0.33 4.11e-10 Lung cancer in ever smokers; LIHC cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg06882758 chr19:58662330 ZNF329 0.92 6.85 0.35 3.54e-11 Cholesterol, total; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg23172400 chr8:95962367 TP53INP1 -0.36 -8.04 -0.4 1.46e-14 Type 2 diabetes; LIHC cis rs11031096 0.678 rs11031219 chr11:4197578 G/A cg18678763 chr11:4115507 RRM1 -0.41 -5.95 -0.31 6.62e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs8062405 1.000 rs8055138 chr16:28891465 C/T cg16576597 chr16:28551801 NUPR1 0.38 6.23 0.32 1.39e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs12478296 1.000 rs12474070 chr2:243039738 C/T cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.95e-15 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27367952 chr2:219221586 C2orf62 0.56 8.12 0.4 8.5e-15 Pancreatic cancer; LIHC cis rs9393777 0.623 rs9366658 chr6:26469866 G/A cg12826209 chr6:26865740 GUSBL1 0.65 6.86 0.35 3.17e-11 Intelligence (multi-trait analysis); LIHC cis rs12594515 1.000 rs6493175 chr15:45989898 T/C cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg02290350 chr8:58132656 NA 0.43 8.86 0.43 4.56e-17 Developmental language disorder (linguistic errors); LIHC cis rs72827839 0.516 rs72833461 chr17:45938105 T/G cg02219949 chr17:45927392 SP6 0.43 5.73 0.3 2.26e-8 Ease of getting up in the morning; LIHC cis rs11724804 0.532 rs73207782 chr4:848764 G/C cg08222618 chr4:941054 TMEM175 0.54 6.63 0.34 1.28e-10 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs13190036 0.748 rs28395268 chr5:176710547 C/G cg06532880 chr5:176731545 PRELID1;RAB24 -0.44 -6.3 -0.32 9.16e-10 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08206623 chr11:2907334 CDKN1C -0.46 -6.99 -0.35 1.4e-11 Cognitive function; LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg13409248 chr3:40428643 ENTPD3 0.49 8.22 0.41 4.34e-15 Renal cell carcinoma; LIHC cis rs1008375 1.000 rs10012335 chr4:17628630 C/G cg16339924 chr4:17578868 LAP3 0.44 6.22 0.32 1.48e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3764618 1.000 rs7409311 chr19:49492822 G/A cg14640682 chr19:49496473 GYS1;RUVBL2 -0.78 -6.14 -0.32 2.3e-9 Follicule stimulating hormone; LIHC cis rs6582630 0.621 rs10880656 chr12:38571220 A/C cg26384229 chr12:38710491 ALG10B -0.47 -6.55 -0.33 2.06e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs600806 0.850 rs11102981 chr1:109967323 G/C cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.84 -0.3 1.2e-8 Intelligence (multi-trait analysis); LIHC cis rs546131 0.642 rs12291580 chr11:34846732 A/G cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.53 -0.33 2.4e-10 Lung disease severity in cystic fibrosis; LIHC cis rs2257205 0.667 rs28380401 chr17:56755613 T/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.68 -0.34 9.69e-11 Pancreatic cancer; LIHC trans rs7618501 0.669 rs7634084 chr3:49949834 A/T cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.42 0.45 7.03e-19 Intelligence (multi-trait analysis); LIHC cis rs7927771 0.832 rs4752994 chr11:47411065 A/T cg20307385 chr11:47447363 PSMC3 0.45 5.87 0.3 1.02e-8 Subjective well-being; LIHC cis rs6121246 1.000 rs6121246 chr20:30433352 C/T cg13852791 chr20:30311386 BCL2L1 0.86 9.05 0.44 1.12e-17 Mean corpuscular hemoglobin; LIHC cis rs875971 0.862 rs28491091 chr7:65669064 G/T cg11764359 chr7:65958608 NA -0.75 -12.45 -0.56 1.34e-29 Aortic root size; LIHC cis rs7474896 0.515 rs2505233 chr10:38340265 C/T cg25427524 chr10:38739819 LOC399744 -0.44 -5.86 -0.3 1.07e-8 Obesity (extreme); LIHC cis rs9640161 0.789 rs10282458 chr7:150045302 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.41 -6.7 -0.34 8.61e-11 Blood protein levels;Circulating chemerin levels; LIHC cis rs6545883 1.000 rs778758 chr2:61782161 T/C cg14146966 chr2:61757674 XPO1 0.49 8.39 0.41 1.32e-15 Tuberculosis; LIHC cis rs798554 0.836 rs798490 chr7:2801542 C/T cg13628971 chr7:2884303 GNA12 0.52 7.78 0.39 8.45e-14 Height; LIHC cis rs67311347 0.822 rs9826847 chr3:40345312 A/T cg00656387 chr3:40428638 ENTPD3 0.38 5.96 0.31 6.26e-9 Renal cell carcinoma; LIHC cis rs826838 1.000 rs12366971 chr12:38737687 T/G cg26384229 chr12:38710491 ALG10B 1.07 14.92 0.63 3.91e-39 Heart rate; LIHC cis rs4862750 0.914 rs11943333 chr4:187872455 A/G cg10295955 chr4:187884368 NA -0.77 -14.79 -0.62 1.3e-38 Lobe attachment (rater-scored or self-reported); LIHC trans rs75804782 0.521 rs56387296 chr2:239426298 A/G cg01134436 chr17:81009848 B3GNTL1 0.75 6.44 0.33 3.99e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs11229030 0.893 rs2264054 chr11:57209488 G/A cg00522883 chr11:57194120 SLC43A3 -0.42 -5.97 -0.31 6.08e-9 Crohn's disease; LIHC cis rs3815700 1.000 rs7247420 chr19:33096786 G/A cg02997394 chr19:33096574 ANKRD27 0.73 9.2 0.45 3.65e-18 Eosinophilic esophagitis; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg00280220 chr17:61926910 NA 0.43 6.87 0.35 3.04e-11 Prudent dietary pattern; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs6867032 0.527 rs4371796 chr5:1977785 C/T cg26168224 chr5:2018326 NA -0.28 -6.28 -0.32 1.05e-9 Gut microbiome composition (winter); LIHC cis rs7577696 0.539 rs13010405 chr2:32338204 A/T cg02381751 chr2:32503542 YIPF4 -0.43 -6.0 -0.31 4.89e-9 Inflammatory biomarkers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12774921 chr16:89608299 SPG7 0.48 7.27 0.37 2.52e-12 Pancreatic cancer; LIHC cis rs9649465 0.967 rs13244694 chr7:123329879 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.02e-15 Migraine; LIHC cis rs548181 0.736 rs543389 chr11:125464841 A/G cg03464685 chr11:125439445 EI24 1.13 10.92 0.51 4.98e-24 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4820294 1.000 rs732856 chr22:38060691 C/G cg26138144 chr22:38071188 LGALS1 -0.76 -14.37 -0.61 5.81e-37 Fat distribution (HIV); LIHC cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 11.75 0.54 5.15e-27 Platelet count; LIHC cis rs2404602 0.716 rs4079681 chr15:76695230 G/A cg03037974 chr15:76606532 NA 0.8 16.65 0.67 5.49e-46 Blood metabolite levels; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg19226866 chr11:63993875 NUDT22;TRPT1 0.51 6.57 0.33 1.84e-10 Hepatitis; LIHC cis rs6586163 0.967 rs10887877 chr10:90753038 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.56 -8.3 -0.41 2.48e-15 Chronic lymphocytic leukemia; LIHC trans rs877282 0.945 rs10904555 chr10:787740 C/A cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs9303401 0.659 rs62083525 chr17:56658088 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.29 0.55 5.1e-29 Cognitive test performance; LIHC cis rs9513627 1.000 rs7338335 chr13:100125296 G/C cg25919922 chr13:100150906 NA -0.76 -6.66 -0.34 1.07e-10 Obesity-related traits; LIHC cis rs4478037 0.642 rs77202692 chr3:33115776 A/C cg16652328 chr3:33138982 GLB1;TMPPE -0.6 -8.32 -0.41 2.17e-15 Major depressive disorder; LIHC cis rs9768139 0.733 rs921617 chr7:158118198 A/G cg06219351 chr7:158114137 PTPRN2 -0.21 -6.02 -0.31 4.53e-9 Calcium levels; LIHC cis rs4934494 0.723 rs17127001 chr10:91522689 G/A cg19698084 chr10:91461284 KIF20B -0.44 -5.88 -0.3 9.5e-9 Red blood cell count; LIHC cis rs2243480 0.708 rs13242216 chr7:65898277 T/C cg07424592 chr7:64974309 NA 0.81 9.12 0.44 6.81e-18 Diabetic kidney disease; LIHC cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.68 0.34 9.67e-11 Bipolar disorder; LIHC cis rs9911578 1.000 rs1494977 chr17:56863064 C/T cg05425664 chr17:57184151 TRIM37 -0.58 -8.53 -0.42 4.83e-16 Intelligence (multi-trait analysis); LIHC cis rs55665837 0.540 rs4757261 chr11:14669802 C/A cg00085434 chr11:14927489 NA 0.41 5.81 0.3 1.41e-8 Vitamin D levels; LIHC cis rs11690935 0.879 rs13017585 chr2:172721808 C/A cg13550731 chr2:172543902 DYNC1I2 -0.96 -17.1 -0.68 8.44e-48 Schizophrenia; LIHC cis rs5769765 0.955 rs9616394 chr22:50314927 G/C cg26441486 chr22:50317300 CRELD2 0.36 5.77 0.3 1.77e-8 Schizophrenia; LIHC trans rs12310956 0.532 rs1525903 chr12:33964163 T/C cg26384229 chr12:38710491 ALG10B 0.49 6.69 0.34 9.13e-11 Morning vs. evening chronotype; LIHC trans rs1493916 0.744 rs7504560 chr18:31312148 A/G cg27147174 chr7:100797783 AP1S1 -0.46 -6.53 -0.33 2.43e-10 Life satisfaction; LIHC cis rs3820068 0.581 rs16851876 chr1:15950628 A/T cg17385448 chr1:15911702 AGMAT -0.35 -6.09 -0.31 3.12e-9 Systolic blood pressure; LIHC cis rs763121 0.962 rs138703 chr22:39132748 C/T cg06022373 chr22:39101656 GTPBP1 0.58 10.7 0.5 3.04e-23 Menopause (age at onset); LIHC cis rs7523273 0.565 rs2796280 chr1:207889345 C/T cg22525895 chr1:207977042 MIR29B2 -0.53 -7.99 -0.4 2.14e-14 Schizophrenia; LIHC cis rs12048904 0.505 rs11166511 chr1:101240686 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.52 -8.41 -0.41 1.12e-15 Multiple sclerosis; LIHC cis rs2303759 0.918 rs10405465 chr19:49869298 C/T cg22590775 chr19:49891494 CCDC155 0.45 7.49 0.38 5.81e-13 Multiple sclerosis; LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs9303280 0.806 rs11078928 chr17:38064469 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.87 0.3 1.01e-8 Self-reported allergy; LIHC cis rs67311347 1.000 rs2305522 chr3:40429358 A/G cg16822855 chr3:40428330 ENTPD3 0.33 5.97 0.31 5.81e-9 Renal cell carcinoma; LIHC cis rs477692 0.612 rs58103386 chr10:131319958 C/A cg05714579 chr10:131428358 MGMT 0.41 6.71 0.34 7.86e-11 Response to temozolomide; LIHC cis rs4631830 0.720 rs898343 chr10:51505403 A/G cg16070123 chr10:51489643 NA 0.38 6.03 0.31 4.15e-9 Prostate-specific antigen levels; LIHC cis rs10752881 0.935 rs3935221 chr1:182969010 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.36 0.49 4.72e-22 Colorectal cancer; LIHC trans rs11039798 1.000 rs7104642 chr11:48588534 C/T cg15704280 chr7:45808275 SEPT13 0.62 6.44 0.33 4.13e-10 Axial length; LIHC cis rs7917772 0.582 rs10786685 chr10:104323103 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.57 0.38 3.61e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs67311347 0.866 rs9826419 chr3:40352051 G/A cg18306943 chr3:40428807 ENTPD3 0.35 5.84 0.3 1.18e-8 Renal cell carcinoma; LIHC trans rs3960554 0.932 rs76873475 chr7:75829199 C/A cg19862616 chr7:65841803 NCRNA00174 0.56 7.74 0.39 1.11e-13 Eotaxin levels; LIHC cis rs1555322 0.530 rs7004 chr20:33866753 G/C cg08210727 chr20:33865349 NA 0.5 5.77 0.3 1.81e-8 Attention deficit hyperactivity disorder; LIHC cis rs3806843 0.735 rs801189 chr5:140063091 A/G cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.6e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1555322 0.530 rs2425044 chr20:33869735 C/T cg07134254 chr20:33865797 NA 0.53 6.27 0.32 1.11e-9 Attention deficit hyperactivity disorder; LIHC cis rs13217239 0.621 rs12527231 chr6:27001288 G/A cg12292205 chr6:26970375 C6orf41 0.44 7.6 0.38 2.95e-13 Schizophrenia; LIHC cis rs7075426 0.905 rs11202038 chr10:88204877 C/T cg07322936 chr10:88137208 NA 0.5 7.06 0.36 9.3e-12 Migraine without aura; LIHC cis rs7131987 0.903 rs11050152 chr12:29404424 G/T cg16970926 chr12:29381810 FAR2 0.3 6.4 0.33 5.26e-10 QT interval; LIHC cis rs7116495 0.867 rs60461859 chr11:71576918 G/A cg26138937 chr11:71823887 C11orf51 0.76 6.65 0.34 1.17e-10 Severe influenza A (H1N1) infection; LIHC cis rs17152411 1.000 rs11245451 chr10:126661428 C/T cg07906193 chr10:126599966 NA 0.51 7.94 0.39 2.88e-14 Height; LIHC cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 -0.76 -7.6 -0.38 2.89e-13 Platelet count; LIHC cis rs67311347 0.869 rs6790495 chr3:40366770 C/T cg18306943 chr3:40428807 ENTPD3 0.36 6.1 0.31 2.84e-9 Renal cell carcinoma; LIHC cis rs4970988 0.556 rs6695123 chr1:150563483 T/C cg13175981 chr1:150552382 MCL1 0.52 7.08 0.36 8.05e-12 Urate levels; LIHC cis rs9814567 1.000 rs7356093 chr3:134238753 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs769267 0.930 rs4808955 chr19:19552413 T/C cg03709012 chr19:19516395 GATAD2A 1.01 18.46 0.71 2.79e-53 Tonsillectomy; LIHC cis rs1401454 1.000 rs1401454 chr11:16250183 C/T cg02656851 chr11:16430247 SOX6 -0.33 -6.23 -0.32 1.35e-9 Blood pressure; LIHC cis rs6918586 0.636 rs198857 chr6:26102417 G/C cg18357526 chr6:26021779 HIST1H4A -0.56 -8.3 -0.41 2.45e-15 Schizophrenia; LIHC cis rs40363 0.645 rs250627 chr16:3527050 G/A cg21433313 chr16:3507492 NAT15 0.48 7.81 0.39 6.9e-14 Tuberculosis; LIHC cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.47 -6.73 -0.34 7.04e-11 Gut microbiome composition (summer); LIHC cis rs17685 0.753 rs1806885 chr7:75785612 T/G cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg13271783 chr10:134563150 INPP5A -0.6 -7.19 -0.36 4.03e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg00280220 chr17:61926910 NA 0.43 6.74 0.34 6.62e-11 Prudent dietary pattern; LIHC cis rs1982963 0.901 rs1566131 chr14:52514684 G/A cg10843707 chr14:52510701 NID2 -0.5 -8.81 -0.43 6.53e-17 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg13607699 chr17:42295918 UBTF 0.45 7.17 0.36 4.6e-12 Total body bone mineral density; LIHC cis rs644799 1.000 rs534497 chr11:95562868 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.76 0.47 5.37e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05329982 chr11:62359210 TUT1 0.45 6.98 0.35 1.54e-11 Cognitive function; LIHC cis rs7296418 0.961 rs1727307 chr12:123575742 A/G cg06742321 chr12:123595122 PITPNM2 0.33 6.16 0.32 2.1e-9 Platelet count; LIHC cis rs4805272 0.512 rs66830923 chr19:29321277 C/T cg04546413 chr19:29218101 NA 0.44 7.39 0.37 1.13e-12 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs910316 0.967 rs11159121 chr14:75666029 A/T cg11812906 chr14:75593930 NEK9 -0.66 -12.55 -0.56 5.79e-30 Height; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg21914477 chr6:5067092 NA 0.42 6.45 0.33 3.91e-10 Longevity; LIHC cis rs2074193 1.000 rs2074193 chr12:47771429 T/G cg02516419 chr12:47771422 NA 0.51 7.73 0.39 1.22e-13 Migraine with aura; LIHC cis rs17376456 0.877 rs35075119 chr5:93385457 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg07061783 chr6:25882402 NA -0.48 -6.73 -0.34 7.17e-11 Blood metabolite levels; LIHC cis rs2204008 0.606 rs6582502 chr12:38543352 C/T cg26384229 chr12:38710491 ALG10B -0.49 -6.79 -0.34 4.84e-11 Bladder cancer; LIHC cis rs7937682 0.889 rs10789844 chr11:111579109 A/T cg09085632 chr11:111637200 PPP2R1B -1.08 -16.68 -0.67 3.84e-46 Primary sclerosing cholangitis; LIHC cis rs9814567 0.806 rs7626557 chr3:134318213 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.73 -0.3 2.26e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10876993 0.855 rs1678520 chr12:58049319 C/G cg18357645 chr12:58087776 OS9 0.54 8.72 0.43 1.22e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs6088590 1.000 rs2295354 chr20:33356541 T/C cg24642439 chr20:33292090 TP53INP2 0.78 10.69 0.5 3.41e-23 Coronary artery disease; LIHC cis rs4908768 0.539 rs7526171 chr1:8650185 T/C cg20416874 chr1:8611966 RERE -0.65 -12.11 -0.55 2.4e-28 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1816752 0.905 rs7400631 chr13:24990065 A/G cg22771759 chr13:24902376 NA 0.33 6.66 0.34 1.1e-10 Obesity-related traits; LIHC cis rs16958440 0.737 rs16950096 chr18:44745546 T/C cg17192377 chr18:44677553 HDHD2 0.73 5.76 0.3 1.87e-8 Sitting height ratio; LIHC cis rs17106184 1.000 rs12073283 chr1:51219188 C/G cg07174182 chr1:51127561 FAF1 -0.63 -6.86 -0.35 3.32e-11 Type 2 diabetes; LIHC cis rs7119038 0.774 rs2004781 chr11:118619253 C/T cg19308663 chr11:118741387 NA 0.43 5.76 0.3 1.86e-8 Sjögren's syndrome; LIHC cis rs2463822 1.000 rs11231050 chr11:62131660 C/G cg06239285 chr11:62104954 ASRGL1 -0.88 -6.61 -0.34 1.46e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2576037 0.501 rs7245049 chr18:44528213 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.68 10.72 0.5 2.54e-23 Personality dimensions; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg27115996 chr7:102741563 NAPEPLD 0.34 6.07 0.31 3.34e-9 Hepatitis; LIHC cis rs910316 0.967 rs175498 chr14:75536369 G/A cg08847533 chr14:75593920 NEK9 -0.89 -19.7 -0.73 2.72e-58 Height; LIHC cis rs7187994 0.848 rs34179694 chr16:84776522 A/G cg07647771 chr16:84786436 USP10 -0.35 -7.01 -0.35 1.32e-11 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs6429082 0.764 rs2481095 chr1:235695756 T/C cg26050004 chr1:235667680 B3GALNT2 -0.43 -6.7 -0.34 8.55e-11 Adiposity; LIHC cis rs9910055 0.530 rs11656758 chr17:42301541 A/G cg13607699 chr17:42295918 UBTF 0.66 11.69 0.53 8.98e-27 Total body bone mineral density; LIHC cis rs9640161 0.750 rs11765644 chr7:150026339 C/G cg10018233 chr7:150070692 REPIN1 0.52 8.05 0.4 1.39e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg06420487 chr17:61919686 SMARCD2 0.45 6.11 0.31 2.68e-9 Height; LIHC cis rs74181299 0.684 rs10185243 chr2:65355744 G/T cg05010058 chr2:65284262 CEP68 -0.39 -6.56 -0.33 1.94e-10 Pulse pressure; LIHC cis rs6733011 0.508 rs4850889 chr2:99521385 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.2 -0.32 1.58e-9 Bipolar disorder; LIHC cis rs6831256 0.550 rs9993109 chr4:3473659 A/G cg23495837 chr4:3480318 DOK7 -0.35 -5.88 -0.3 9.83e-9 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs1882538 0.538 rs7783217 chr7:133104117 C/G cg10665199 chr7:133106180 EXOC4 -0.49 -8.11 -0.4 9.23e-15 Intelligence (multi-trait analysis); LIHC cis rs10752881 0.775 rs2147585 chr1:183074875 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.93 0.51 4.56e-24 Colorectal cancer; LIHC cis rs9322817 0.691 rs2290515 chr6:105232204 C/T cg02098413 chr6:105308735 HACE1 -0.43 -7.85 -0.39 5.55e-14 Thyroid stimulating hormone; LIHC cis rs11931598 0.511 rs4689576 chr4:7025523 T/C cg02503808 chr4:7069936 GRPEL1 0.45 7.04 0.36 1.07e-11 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs13191362 0.810 rs28360533 chr6:162996742 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.92 0.3 7.85e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1728785 0.901 rs1645934 chr16:68564490 T/A cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs1941023 0.584 rs4938941 chr11:60173360 C/T cg08716584 chr11:60157161 MS4A7 0.37 8.39 0.41 1.26e-15 Congenital heart disease (maternal effect); LIHC cis rs3741404 0.609 rs635139 chr11:63872210 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 11.06 0.51 1.58e-24 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01934856 chr1:10720466 CASZ1 -0.44 -6.96 -0.35 1.76e-11 Lung function (FEV1/FVC); LIHC cis rs6121246 0.909 rs6088962 chr20:30268184 C/T cg13852791 chr20:30311386 BCL2L1 0.9 8.61 0.42 2.72e-16 Mean corpuscular hemoglobin; LIHC cis rs4332037 0.707 rs11763813 chr7:1896690 C/T cg23422044 chr7:1970798 MAD1L1 -0.6 -6.79 -0.34 4.92e-11 Bipolar disorder; LIHC cis rs77633900 0.772 rs16968196 chr15:76682238 C/T cg21673338 chr15:77095150 SCAPER -0.53 -5.93 -0.31 7.22e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs9457247 0.765 rs9457256 chr6:167436461 T/C cg23791538 chr6:167370224 RNASET2 -0.52 -7.88 -0.39 4.34e-14 Crohn's disease; LIHC trans rs6489882 0.902 rs3759375 chr12:113373588 A/G cg10175203 chr3:128143634 NA 0.38 6.19 0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg23978390 chr7:1156363 C7orf50 0.55 8.58 0.42 3.25e-16 Longevity;Endometriosis; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg19056506 chr17:79633562 CCDC137;C17orf90 0.46 6.27 0.32 1.08e-9 Glycated hemoglobin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04362369 chr14:21905501 CHD8 0.49 6.18 0.32 1.77e-9 Lung function (FEV1/FVC); LIHC cis rs7568458 0.684 rs3731828 chr2:85806266 C/T cg02493740 chr2:85810744 VAMP5 -0.47 -7.82 -0.39 6.79e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs6952808 0.636 rs6964522 chr7:1953523 C/T cg14004847 chr7:1930337 MAD1L1 -0.55 -8.12 -0.4 8.49e-15 Bipolar disorder and schizophrenia; LIHC cis rs4407350 0.682 rs135624 chr22:44890685 C/G cg26276947 chr22:44892394 LDOC1L -0.33 -6.37 -0.33 6.08e-10 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg07677032 chr17:61819896 STRADA 0.42 6.1 0.31 2.82e-9 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg25894440 chr7:65020034 NA -0.55 -6.3 -0.32 8.92e-10 Diabetic kidney disease; LIHC cis rs9303401 0.659 rs62081314 chr17:56778328 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.95 12.98 0.57 1.33e-31 Cognitive test performance; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg11905131 chr22:24372483 LOC391322 -0.72 -10.64 -0.5 4.82e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17776563 0.887 rs72763817 chr15:89141238 C/G cg05013243 chr15:89149849 MIR1179 0.42 6.92 0.35 2.18e-11 Thyroid hormone levels; LIHC cis rs15676 1.000 rs15676 chr9:131572027 A/G cg00228799 chr9:131580591 ENDOG -0.45 -7.05 -0.36 1.02e-11 Blood metabolite levels; LIHC cis rs2952156 0.684 rs1877031 chr17:37814080 G/A cg00129232 chr17:37814104 STARD3 -0.6 -11.61 -0.53 1.76e-26 Asthma; LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg05185784 chr16:90016020 DEF8 -0.47 -6.08 -0.31 3.18e-9 Skin colour saturation; LIHC cis rs6752107 1.000 rs12994971 chr2:234178453 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.31 0.41 2.33e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10911232 0.507 rs10752888 chr1:182993751 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.25 0.48 1.08e-21 Hypertriglyceridemia; LIHC cis rs16854884 0.657 rs35788195 chr3:143739311 C/T cg06585982 chr3:143692056 C3orf58 0.49 6.12 0.31 2.56e-9 Economic and political preferences (feminism/equality); LIHC cis rs4727027 0.704 rs12537763 chr7:148903984 G/A cg23583168 chr7:148888333 NA -0.77 -11.88 -0.54 1.7e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs11025559 0.812 rs10833336 chr11:20514288 C/G cg19653624 chr11:20408972 PRMT3 -0.47 -6.18 -0.32 1.86e-9 Pursuit maintenance gain; LIHC cis rs9916302 0.904 rs2061338 chr17:37421767 T/C cg00129232 chr17:37814104 STARD3 -0.39 -6.33 -0.32 7.5e-10 Glomerular filtration rate (creatinine); LIHC cis rs765787 0.530 rs12917187 chr15:45538297 A/G cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs1419980 0.730 rs7962586 chr12:7772315 G/A cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs9640161 0.783 rs1132261 chr7:150059987 G/A cg21361702 chr7:150065534 REPIN1 0.53 7.5 0.38 5.39e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs7512552 0.839 rs6662108 chr1:150420541 G/T cg15654264 chr1:150340011 RPRD2 0.69 11.74 0.54 5.61e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9457247 0.765 rs6900701 chr6:167434112 A/G cg07741184 chr6:167504864 NA 0.31 7.33 0.37 1.71e-12 Crohn's disease; LIHC cis rs2806561 0.704 rs2868573 chr1:23508253 C/G cg19743168 chr1:23544995 NA 0.34 5.72 0.3 2.33e-8 Height; LIHC cis rs10744422 0.748 rs1671688 chr12:123255733 A/T cg22842854 chr12:123319900 HIP1R -0.64 -8.07 -0.4 1.24e-14 Schizophrenia; LIHC cis rs17106184 1.000 rs3789576 chr1:50945526 G/T cg07174182 chr1:51127561 FAF1 -0.61 -6.85 -0.35 3.54e-11 Type 2 diabetes; LIHC cis rs3806843 1.000 rs4404730 chr5:140162610 G/A cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.4e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7945718 0.621 rs7931351 chr11:12692162 A/T cg25843174 chr11:12811716 TEAD1 0.35 7.98 0.4 2.22e-14 Educational attainment (years of education); LIHC cis rs2842992 0.830 rs1853259 chr6:160147441 A/G cg11366901 chr6:160182831 ACAT2 -0.96 -16.32 -0.66 1.1e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs8016982 0.531 rs2241622 chr14:81737290 A/G cg01989461 chr14:81687754 GTF2A1 0.51 8.37 0.41 1.49e-15 Schizophrenia; LIHC cis rs546131 0.642 rs1897203 chr11:34821988 C/T cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.41 -0.33 4.91e-10 Lung disease severity in cystic fibrosis; LIHC cis rs11864453 0.679 rs2303285 chr16:72124495 A/C cg16558253 chr16:72132732 DHX38 -0.45 -7.26 -0.37 2.55e-12 Fibrinogen levels; LIHC cis rs6442522 0.809 rs13081119 chr3:15451021 A/C cg16303742 chr3:15540471 COLQ -0.38 -6.15 -0.32 2.12e-9 Uric acid levels; LIHC cis rs10751667 0.666 rs4074234 chr11:977715 C/G ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs929354 0.772 rs3802117 chr7:156987000 C/T cg16102536 chr7:156981717 UBE3C 0.35 5.92 0.3 7.91e-9 Body mass index; LIHC cis rs1005277 0.579 rs2800485 chr10:38542588 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.37 -0.33 5.99e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2228479 0.850 rs11076623 chr16:89844120 G/T cg06558623 chr16:89946397 TCF25 0.87 11.66 0.53 1.1e-26 Skin colour saturation; LIHC cis rs7927771 0.864 rs2053979 chr11:47439444 A/G cg20135002 chr11:47629003 NA -0.57 -9.63 -0.46 1.43e-19 Subjective well-being; LIHC cis rs17106184 1.000 rs58446086 chr1:50971801 A/G cg07174182 chr1:51127561 FAF1 -0.64 -6.76 -0.34 6.13e-11 Type 2 diabetes; LIHC cis rs4319547 0.656 rs3817011 chr12:122819566 C/T cg23029597 chr12:123009494 RSRC2 -0.5 -7.12 -0.36 6.31e-12 Body mass index; LIHC cis rs782590 0.967 rs1975484 chr2:55803167 T/A cg03859395 chr2:55845619 SMEK2 0.86 15.43 0.64 4.04e-41 Metabolic syndrome; LIHC cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg27286337 chr10:134555280 INPP5A 0.93 13.39 0.59 3.79e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.57 0.46 2.29e-19 Height; LIHC cis rs4759375 1.000 rs11057223 chr12:123755055 T/C cg00376283 chr12:123451042 ABCB9 -0.5 -6.25 -0.32 1.24e-9 HDL cholesterol; LIHC cis rs9394841 0.692 rs9357371 chr6:41885319 A/C cg17623882 chr6:41773611 USP49 -0.45 -6.05 -0.31 3.72e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs7095944 0.614 rs12570348 chr10:126438963 A/C cg08799069 chr10:126477246 METTL10 0.35 6.03 0.31 4.17e-9 Asthma; LIHC cis rs769267 0.896 rs2074298 chr19:19377716 C/G cg03709012 chr19:19516395 GATAD2A 0.93 15.11 0.63 7.03e-40 Tonsillectomy; LIHC cis rs9527 0.668 rs7092815 chr10:104736345 G/T cg15744005 chr10:104629667 AS3MT -0.31 -6.19 -0.32 1.74e-9 Arsenic metabolism; LIHC cis rs4819052 0.851 rs4819043 chr21:46660078 G/A cg22633049 chr21:46681294 NA -0.37 -6.31 -0.32 8.65e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs311392 0.966 rs425548 chr8:55087468 C/T cg20636351 chr8:55087400 NA -0.4 -8.06 -0.4 1.31e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs4073582 0.595 rs2508657 chr11:66043898 G/A cg14036092 chr11:66035641 RAB1B 0.46 6.75 0.34 6.3e-11 Gout; LIHC cis rs77633900 0.614 rs2930681 chr15:76995150 G/A cg21673338 chr15:77095150 SCAPER -0.49 -7.52 -0.38 4.89e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg06466757 chr4:1255808 NA -0.34 -5.78 -0.3 1.7e-8 Obesity-related traits; LIHC cis rs2795502 1.000 rs1852959 chr10:43359636 T/C cg20628663 chr10:43360327 NA 0.46 7.07 0.36 8.97e-12 Blood protein levels; LIHC cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg20607798 chr8:58055168 NA 0.49 6.23 0.32 1.34e-9 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.712 rs1859792 chr7:75789264 T/C cg01364799 chr7:75623366 TMEM120A -0.43 -6.36 -0.33 6.51e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs881375 0.678 rs1014530 chr9:123685092 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.42 6.16 0.32 2.03e-9 Rheumatoid arthritis; LIHC cis rs17253792 0.822 rs79921041 chr14:56090779 T/C cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14426781 chr11:129149366 NA 0.42 6.06 0.31 3.68e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17345786 0.861 rs17402964 chr3:101067945 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.58 7.32 0.37 1.79e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs11122272 0.701 rs2790894 chr1:231505587 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.57 -0.5 8.95e-23 Hemoglobin concentration; LIHC cis rs16854884 0.657 rs1867608 chr3:143752938 G/A cg06585982 chr3:143692056 C3orf58 0.54 7.07 0.36 8.83e-12 Economic and political preferences (feminism/equality); LIHC cis rs10876993 0.789 rs1689600 chr12:58049645 A/T cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.79 -0.34 5.05e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs9918079 0.560 rs4270584 chr4:15600799 A/G cg21123203 chr4:15471301 CC2D2A 0.47 7.51 0.38 5.29e-13 Obesity-related traits; LIHC cis rs11105298 0.786 rs3803128 chr12:89860319 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.54 -0.38 4.24e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs826838 0.900 rs9739128 chr12:38948960 A/T cg26384229 chr12:38710491 ALG10B 0.95 13.02 0.58 9.71e-32 Heart rate; LIHC cis rs1371867 0.846 rs1788203 chr8:101303721 T/C cg06636551 chr8:101224915 SPAG1 -0.5 -9.06 -0.44 1.02e-17 Atrioventricular conduction; LIHC cis rs1997103 0.911 rs10238738 chr7:55412359 T/C cg17469321 chr7:55412551 NA 0.49 7.19 0.36 3.98e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6545883 0.929 rs3732171 chr2:61749690 C/T cg15711740 chr2:61764176 XPO1 -0.43 -6.15 -0.32 2.12e-9 Tuberculosis; LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg21448741 chr8:58168803 NA -0.35 -6.55 -0.33 2.17e-10 Developmental language disorder (linguistic errors); LIHC cis rs17376456 0.825 rs12188163 chr5:93250608 A/G cg25358565 chr5:93447407 FAM172A -1.07 -9.79 -0.47 4.12e-20 Diabetic retinopathy; LIHC cis rs1059312 0.808 rs4760533 chr12:129297651 A/G cg09035930 chr12:129282057 SLC15A4 -0.57 -10.94 -0.51 4.3e-24 Systemic lupus erythematosus; LIHC cis rs9649213 0.593 rs6465677 chr7:98003552 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.36 -5.73 -0.3 2.23e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs10197940 0.662 rs2432945 chr2:152278414 T/C cg19508488 chr2:152266495 RIF1 0.58 8.32 0.41 2.13e-15 Lung cancer; LIHC trans rs3960554 0.867 rs11489553 chr7:75843062 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 6.94 0.35 1.94e-11 Eotaxin levels; LIHC cis rs2806561 0.765 rs643492 chr1:23501354 C/T cg19743168 chr1:23544995 NA -0.35 -5.85 -0.3 1.13e-8 Height; LIHC cis rs6582630 0.555 rs6582503 chr12:38557886 A/C cg26384229 chr12:38710491 ALG10B 0.97 12.66 0.56 2.12e-30 Drug-induced liver injury (flucloxacillin); LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 22.89 0.78 5.84e-71 Prudent dietary pattern; LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg13409248 chr3:40428643 ENTPD3 0.46 7.68 0.38 1.64e-13 Renal cell carcinoma; LIHC cis rs1552244 0.572 rs17032440 chr3:10169819 A/C cg02579736 chr3:10068473 FANCD2;CIDECP -0.77 -7.94 -0.39 2.97e-14 Alzheimer's disease; LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg07157834 chr1:205819609 PM20D1 0.71 10.21 0.48 1.49e-21 Menarche (age at onset); LIHC cis rs1843834 1.000 rs4624372 chr2:225553128 A/G cg22509189 chr2:225307070 NA -0.55 -6.81 -0.35 4.28e-11 IgE levels in asthmatics (D.p. specific); LIHC cis rs3812111 0.676 rs1114228 chr6:116502011 T/A cg08036074 chr6:116424633 NT5DC1 -0.52 -8.71 -0.43 1.33e-16 Age-related macular degeneration; LIHC cis rs1385374 0.858 rs12305142 chr12:129277490 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.57 7.18 0.36 4.3e-12 Systemic lupus erythematosus; LIHC cis rs10508774 1.000 rs12247495 chr10:32802829 G/C cg01819863 chr10:32635814 EPC1 0.65 6.08 0.31 3.28e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs67311347 1.000 rs7648952 chr3:40457038 C/T cg09455208 chr3:40491958 NA -0.33 -6.64 -0.34 1.21e-10 Renal cell carcinoma; LIHC cis rs911119 0.866 rs6048925 chr20:23579056 C/A cg16589663 chr20:23618590 CST3 0.66 6.9 0.35 2.51e-11 Chronic kidney disease; LIHC cis rs6701037 0.748 rs10912901 chr1:175138602 G/A cg17845761 chr1:175162550 KIAA0040 -0.43 -7.11 -0.36 6.68e-12 Alcohol dependence; LIHC cis rs244293 0.965 rs244341 chr17:53198922 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.5 -0.38 5.39e-13 Menarche (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg06119275 chr12:133384736 GOLGA3 0.43 6.27 0.32 1.11e-9 Hepatitis; LIHC cis rs35306767 0.855 rs56222464 chr10:867535 C/G cg20503657 chr10:835505 NA 1.34 13.9 0.6 3.84e-35 Eosinophil percentage of granulocytes; LIHC cis rs9443189 0.762 rs2647417 chr6:76435943 A/G cg01950844 chr6:76311363 SENP6 -0.56 -7.23 -0.36 3.11e-12 Prostate cancer; LIHC cis rs1691799 0.899 rs1168307 chr12:66739539 A/G cg16791601 chr12:66731901 HELB -0.57 -13.94 -0.6 2.64e-35 White blood cell count (basophil); LIHC cis rs7249142 0.549 rs539 chr19:19287802 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.87 -0.35 3.08e-11 IgG glycosylation; LIHC cis rs1506636 0.962 rs7811830 chr7:123320183 G/C cg03229431 chr7:123269106 ASB15 -0.61 -12.27 -0.55 6.39e-29 Plateletcrit;Platelet count; LIHC cis rs7903847 0.620 rs10882904 chr10:99115683 A/G cg20016023 chr10:99160130 RRP12 -0.41 -6.31 -0.32 8.81e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs240764 0.658 rs12210255 chr6:101187540 G/C cg09795085 chr6:101329169 ASCC3 -0.46 -6.69 -0.34 9.07e-11 Neuroticism; LIHC cis rs846178 1 rs846178 chr4:2485615 A/C cg16474684 chr4:2470049 RNF4 -0.53 -7.46 -0.37 7.12e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9430161 0.611 rs72644043 chr1:11033051 T/A cg02454025 chr1:11042201 C1orf127 0.95 18.11 0.7 7.3e-52 Ewing sarcoma; LIHC cis rs9393692 0.905 rs6940237 chr6:26282322 T/C cg13736514 chr6:26305472 NA -0.38 -6.39 -0.33 5.41e-10 Educational attainment; LIHC cis rs250677 1.000 rs36080 chr5:148430451 A/G cg18129178 chr5:148520854 ABLIM3 -0.43 -7.03 -0.36 1.14e-11 Breast cancer; LIHC cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg11941060 chr3:133502564 NA -0.4 -5.72 -0.3 2.36e-8 Iron status biomarkers; LIHC cis rs1790761 0.667 rs11227837 chr11:67336424 A/T cg01069141 chr11:67398826 TBX10;NUDT8 0.38 6.72 0.34 7.5e-11 Mean corpuscular volume; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg00280220 chr17:61926910 NA 0.43 7.02 0.35 1.19e-11 Prudent dietary pattern; LIHC trans rs1814175 0.935 rs11040465 chr11:49689323 C/T cg15704280 chr7:45808275 SEPT13 -1.02 -21.83 -0.76 8.53e-67 Height; LIHC cis rs7044106 0.791 rs10818473 chr9:123484155 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 8.06 0.4 1.27e-14 Hip circumference adjusted for BMI; LIHC cis rs9308433 0.529 rs9430131 chr1:214481121 C/A cg06198575 chr1:214491504 SMYD2 0.54 5.72 0.3 2.28e-8 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03909902 chr12:108154529 PRDM4 -0.48 -6.85 -0.35 3.43e-11 Cognitive function; LIHC cis rs2032447 0.639 rs198810 chr6:26128618 A/G cg03517284 chr6:25882590 NA 0.49 6.24 0.32 1.32e-9 Intelligence (multi-trait analysis); LIHC trans rs13113518 0.812 rs13140173 chr4:56393331 C/T cg15358633 chr12:38710606 ALG10B 0.44 6.29 0.32 9.82e-10 Height; LIHC cis rs77633900 0.614 rs280005 chr15:77009185 G/C cg21673338 chr15:77095150 SCAPER -0.49 -7.52 -0.38 4.89e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs10420951 0.617 rs74389203 chr19:18606656 G/A cg10790698 chr19:18539756 SSBP4 -0.42 -5.86 -0.3 1.11e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs539514 0.563 rs7991448 chr13:76334061 G/A cg04757411 chr13:76259545 LMO7 -0.4 -6.67 -0.34 1.03e-10 Type 1 diabetes; LIHC cis rs9420 0.884 rs673344 chr11:57657141 G/A cg19752551 chr11:57585705 CTNND1 0.44 6.24 0.32 1.31e-9 Schizophrenia; LIHC cis rs13266463 0.898 rs13267784 chr8:143394915 C/T cg16886403 chr8:143471632 TSNARE1 0.49 7.06 0.36 9.46e-12 Schizophrenia; LIHC cis rs526231 0.819 rs411648 chr5:102602902 A/T cg05225461 chr5:102596755 C5orf30 0.38 5.89 0.3 9.25e-9 Primary biliary cholangitis; LIHC cis rs17818399 0.533 rs13420857 chr2:46798005 C/G cg02822958 chr2:46747628 ATP6V1E2 -0.42 -6.88 -0.35 2.92e-11 Height; LIHC cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg06634786 chr22:41940651 POLR3H -0.78 -8.7 -0.43 1.41e-16 Vitiligo; LIHC cis rs1348850 0.872 rs2084233 chr2:178331206 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.9 14.29 0.61 1.24e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs4566357 0.595 rs1320406 chr2:227920474 C/T cg16088116 chr21:44841560 SIK1 -0.39 -6.04 -0.31 4.12e-9 Coronary artery disease; LIHC cis rs11105298 0.891 rs8181784 chr12:89828591 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.54 -6.21 -0.32 1.51e-9 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs950169 0.922 rs4338765 chr15:84916836 G/T cg12863693 chr15:85201151 NMB 0.43 6.13 0.31 2.4e-9 Schizophrenia; LIHC trans rs8073060 0.544 rs225274 chr17:33971221 C/T cg19694781 chr19:47549865 TMEM160 1.16 13.06 0.58 6.69e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs769267 0.930 rs2315022 chr19:19413381 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.1 0.31 2.93e-9 Tonsillectomy; LIHC cis rs7224737 0.956 rs8081327 chr17:40274200 G/A cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs7116495 1.000 rs7937582 chr11:71744613 C/T cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs17854409 0.803 rs1048100 chr20:61472073 C/A cg05147244 chr20:61493195 TCFL5 1.19 10.9 0.51 5.99e-24 Obesity-related traits; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg03685817 chr19:32876832 ZNF507 -0.27 -6.47 -0.33 3.31e-10 Calcium levels; LIHC cis rs35110281 0.807 rs28840140 chr21:45039163 T/C cg21573476 chr21:45109991 RRP1B -0.53 -10.07 -0.48 4.64e-21 Mean corpuscular volume; LIHC cis rs1577917 1.000 rs12213149 chr6:86668644 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.83 -0.35 3.94e-11 Response to antipsychotic treatment; LIHC cis rs16944613 0.510 rs7163773 chr15:91144486 G/C cg26821196 chr15:91095069 CRTC3 0.32 5.99 0.31 5.4e-9 Colorectal cancer; LIHC cis rs1198430 0.759 rs1198438 chr1:23749557 C/G cg19827787 chr1:23763612 ASAP3 0.27 5.97 0.31 5.85e-9 Total cholesterol levels; LIHC cis rs2075371 1.000 rs1421485 chr7:133985181 C/T cg20476274 chr7:133979776 SLC35B4 0.75 12.53 0.56 6.44e-30 Mean platelet volume; LIHC cis rs9372253 0.967 rs9400379 chr6:110713783 A/G cg19196401 chr6:110721138 DDO -0.3 -5.94 -0.31 6.9e-9 Platelet distribution width; LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg06656553 chr16:89960601 TCF25 -0.5 -6.45 -0.33 3.81e-10 Skin colour saturation; LIHC cis rs13062095 0.505 rs2553425 chr3:101103623 C/G cg19452782 chr3:101232218 SENP7 -0.41 -6.12 -0.31 2.57e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs9393777 0.623 rs3734544 chr6:26468660 G/A cg12826209 chr6:26865740 GUSBL1 0.64 6.84 0.35 3.73e-11 Intelligence (multi-trait analysis); LIHC cis rs1728785 1.000 rs1069288 chr16:68585285 C/G cg02972257 chr16:68554789 NA -0.56 -6.57 -0.33 1.92e-10 Ulcerative colitis; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs12926788 0.542 rs6497759 chr16:24801737 G/A cg04756594 chr16:24857601 SLC5A11 0.6 8.97 0.44 2e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs13161895 0.887 rs1103811 chr5:179413168 G/A cg02702477 chr5:179499311 RNF130 0.64 9.15 0.44 5.18e-18 LDL cholesterol; LIHC cis rs6752107 0.935 rs10929322 chr2:234149702 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 -0.49 -7.34 -0.37 1.55e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1670533 1.000 rs6812586 chr4:1069851 A/G cg27284194 chr4:1044797 NA 0.6 8.88 0.43 3.91e-17 Recombination rate (females); LIHC trans rs2211698 1.000 rs78238889 chr21:35839837 C/T cg18044562 chr7:50468399 IKZF1 0.5 7.13 0.36 6.12e-12 Cancer; LIHC cis rs4974559 0.501 rs2101094 chr4:1235643 A/G cg02980000 chr4:1222292 CTBP1 -0.87 -6.69 -0.34 9.4e-11 Systolic blood pressure; LIHC cis rs892961 0.932 rs3987886 chr17:75414980 A/G cg01320579 chr17:75405842 SEPT9 0.52 7.33 0.37 1.64e-12 Airflow obstruction; LIHC cis rs861020 0.560 rs649275 chr1:209950681 T/C cg05527609 chr1:210001259 C1orf107 0.55 8.71 0.43 1.37e-16 Orofacial clefts; LIHC cis rs2070488 0.965 rs3762791 chr3:38568828 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.47 -0.62 2.32e-37 Electrocardiographic conduction measures; LIHC cis rs763121 0.853 rs138716 chr22:39146527 C/T cg06544989 chr22:39130855 UNC84B 0.39 6.04 0.31 4.07e-9 Menopause (age at onset); LIHC cis rs79149102 0.579 rs76518150 chr15:75292721 C/G cg15902774 chr15:75289873 SCAMP5 0.42 6.05 0.31 3.88e-9 Lung cancer; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg07677032 chr17:61819896 STRADA 0.44 6.42 0.33 4.49e-10 Prudent dietary pattern; LIHC cis rs17384381 1.000 rs12129502 chr1:85900727 T/C cg16011679 chr1:85725395 C1orf52 0.79 8.49 0.42 6.4e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.967 rs7142513 chr14:90705182 T/C cg04374321 chr14:90722782 PSMC1 0.74 14.15 0.61 4.29e-36 Mortality in heart failure; LIHC cis rs1577917 0.876 rs12190735 chr6:86686467 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.54 -9.25 -0.45 2.5e-18 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg11764359 chr7:65958608 NA 0.56 5.96 0.31 6.14e-9 Diabetic kidney disease; LIHC cis rs722599 0.715 rs12147629 chr14:75307588 A/G cg08847533 chr14:75593920 NEK9 -0.54 -8.32 -0.41 2.08e-15 IgG glycosylation; LIHC cis rs8141529 0.764 rs8137969 chr22:29228484 G/C cg02153584 chr22:29168773 CCDC117 0.58 9.27 0.45 2.11e-18 Lymphocyte counts; LIHC cis rs8017423 0.740 rs7152196 chr14:90703900 G/T cg14092571 chr14:90743983 NA -0.38 -6.01 -0.31 4.82e-9 Mortality in heart failure; LIHC cis rs1552244 0.882 rs3732967 chr3:10015437 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs6762 0.748 rs28677123 chr11:840604 C/G cg15787769 chr11:842744 TSPAN4;POLR2L -0.67 -8.08 -0.4 1.14e-14 Mean platelet volume; LIHC cis rs2839186 0.559 rs2277826 chr21:47639492 C/G cg00815214 chr21:47717953 NA 0.35 5.86 0.3 1.08e-8 Testicular germ cell tumor; LIHC cis rs912057 0.932 rs1294404 chr6:6735022 G/A cg06612196 chr6:6737390 NA 0.46 8.32 0.41 2.07e-15 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs4907240 0.922 rs4907246 chr2:97326286 T/C cg26665480 chr2:98280029 ACTR1B -0.41 -6.07 -0.31 3.47e-9 Event-related brain oscillations; LIHC cis rs34172651 0.517 rs34172679 chr16:24840381 C/T cg00152838 chr16:24741724 TNRC6A -0.5 -5.84 -0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs9473924 0.580 rs66462826 chr6:50814877 C/A cg14470998 chr6:50812995 TFAP2B 0.93 10.62 0.5 6.08e-23 Body mass index; LIHC cis rs9790314 0.613 rs6809177 chr3:160630477 G/T cg03342759 chr3:160939853 NMD3 0.56 7.4 0.37 1.04e-12 Morning vs. evening chronotype; LIHC trans rs9929218 0.508 rs6499194 chr16:68744100 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.85 18.26 0.7 1.79e-52 Colorectal cancer; LIHC cis rs7131987 0.868 rs7958210 chr12:29395181 G/C cg14222432 chr12:29376421 FAR2 0.38 7.4 0.37 1.1e-12 QT interval; LIHC cis rs9443189 0.570 rs567903 chr6:76327851 C/T cg01950844 chr6:76311363 SENP6 0.85 10.58 0.5 8.2000000000000006e-23 Prostate cancer; LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg13409248 chr3:40428643 ENTPD3 0.47 7.68 0.38 1.72e-13 Renal cell carcinoma; LIHC cis rs6701037 0.681 rs2285220 chr1:175130773 T/A cg17845761 chr1:175162550 KIAA0040 -0.43 -7.16 -0.36 5.11e-12 Alcohol dependence; LIHC cis rs11030122 0.661 rs10835561 chr11:4087594 C/T cg18678763 chr11:4115507 RRM1 -0.58 -8.81 -0.43 6.51e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs6461049 0.519 rs3778992 chr7:2175313 C/G cg02951883 chr7:2050386 MAD1L1 -0.59 -9.44 -0.45 5.94e-19 Schizophrenia; LIHC cis rs1789 0.786 rs6449161 chr4:15692954 A/G cg21123203 chr4:15471301 CC2D2A -0.44 -6.84 -0.35 3.69e-11 Blood protein levels; LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg26338869 chr17:61819248 STRADA 0.52 6.97 0.35 1.61e-11 Height; LIHC cis rs897984 0.683 rs8046001 chr16:30833321 C/T cg02466173 chr16:30829666 NA -0.48 -8.13 -0.4 7.87e-15 Dementia with Lewy bodies; LIHC cis rs11098499 0.909 rs1546502 chr4:120235898 A/G cg09307838 chr4:120376055 NA 0.74 11.34 0.52 1.62e-25 Corneal astigmatism; LIHC cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg08219700 chr8:58056026 NA 0.53 6.78 0.34 5.4e-11 Developmental language disorder (linguistic errors); LIHC cis rs2257205 0.667 rs9889494 chr17:56629764 T/C cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg23758822 chr17:41437982 NA 0.94 17.64 0.69 5.76e-50 Menopause (age at onset); LIHC cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg17971929 chr21:40555470 PSMG1 0.85 10.53 0.49 1.2e-22 Cognitive function; LIHC trans rs208515 0.556 rs12201658 chr6:66678457 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.75 8.71 0.43 1.36e-16 Exhaled nitric oxide levels; LIHC cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6430585 0.527 rs2304366 chr2:136467119 C/T cg07169764 chr2:136633963 MCM6 0.68 8.62 0.42 2.47e-16 Corneal structure; LIHC cis rs5769765 0.773 rs9616378 chr22:50311973 A/G cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs4819052 0.851 rs7279011 chr21:46655995 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.11 0.36 6.63e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs748404 0.697 rs579651 chr15:43558376 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.28 0.41 2.8e-15 Lung cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17752083 chr10:135101849 TUBGCP2 0.38 6.17 0.32 1.93e-9 Pancreatic cancer; LIHC cis rs8180040 0.932 rs12490058 chr3:47529063 T/C cg27129171 chr3:47204927 SETD2 0.58 9.91 0.47 1.65e-20 Colorectal cancer; LIHC cis rs6089584 0.927 rs1886007 chr20:60581049 G/A cg12751644 chr20:60527061 NA -0.36 -5.96 -0.31 6.13e-9 Body mass index; LIHC cis rs7078219 0.897 rs10883360 chr10:101281158 C/G cg06854084 chr10:101292507 NKX2-3 -0.32 -5.72 -0.3 2.29e-8 Dental caries; LIHC cis rs807669 0.903 rs762527 chr22:19183470 A/G cg02655711 chr22:19163373 SLC25A1 0.73 11.2 0.52 5.32e-25 Metabolite levels; LIHC cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg07414643 chr4:187882934 NA 0.24 6.07 0.31 3.34e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs208520 1.000 rs72880045 chr6:66965232 A/C cg07460842 chr6:66804631 NA 0.65 7.0 0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs972578 1.000 rs1071961 chr22:43349699 C/A cg01576275 chr22:43409880 NA -0.32 -5.71 -0.3 2.45e-8 Mean platelet volume; LIHC cis rs9368481 0.678 rs62402024 chr6:26923976 T/C cg18867708 chr6:26865862 GUSBL1 0.54 8.18 0.4 5.77e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs55702914 0.742 rs6744206 chr2:198148522 A/G cg10820045 chr2:198174542 NA -0.39 -5.98 -0.31 5.55e-9 Major depression and alcohol dependence; LIHC cis rs3849570 0.555 rs6790351 chr3:82008988 C/T cg07356753 chr3:81810745 GBE1 -0.42 -6.45 -0.33 3.89e-10 Waist circumference;Body mass index; LIHC cis rs8114671 0.869 rs2145559 chr20:33651725 G/A cg07148914 chr20:33460835 GGT7 -0.56 -8.31 -0.41 2.2e-15 Height; LIHC cis rs875971 0.545 rs6970498 chr7:65740895 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.17 0.36 4.54e-12 Aortic root size; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13665852 chr10:13146898 OPTN 0.42 6.29 0.32 9.73e-10 Longevity; LIHC cis rs875971 0.545 rs6979636 chr7:65741625 A/G cg11764359 chr7:65958608 NA 0.57 8.04 0.4 1.46e-14 Aortic root size; LIHC cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.18 -0.55 1.33e-28 Alzheimer's disease; LIHC trans rs11157436 0.958 rs17255510 chr14:22662856 C/T cg13567813 chr19:50879636 NR1H2 -0.42 -6.09 -0.31 3.02e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs6951245 0.938 rs112425403 chr7:1071531 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.15 0.32 2.18e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4268898 0.662 rs714531 chr2:24399877 G/A cg06627628 chr2:24431161 ITSN2 -0.69 -8.98 -0.44 1.9e-17 Asthma; LIHC cis rs7481584 0.581 rs105686 chr11:3062467 G/A cg25174290 chr11:3078921 CARS -0.41 -6.16 -0.32 2.01e-9 Calcium levels; LIHC cis rs72653721 0.617 rs60043068 chr6:11035426 A/C cg13562911 chr6:11044106 ELOVL2 0.39 5.79 0.3 1.56e-8 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg06238570 chr21:40685208 BRWD1 0.56 6.79 0.34 4.99e-11 Cognitive function; LIHC cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg00934597 chr7:893267 UNC84A -0.64 -9.66 -0.46 1.15e-19 Perceived unattractiveness to mosquitoes; LIHC cis rs950169 0.580 rs1061737 chr15:85183790 G/C cg17507749 chr15:85114479 UBE2QP1 0.7 7.87 0.39 4.7e-14 Schizophrenia; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg26168469 chr14:96505617 C14orf132 0.44 6.05 0.31 3.75e-9 Myopia (pathological); LIHC trans rs1814175 0.817 rs10839318 chr11:49657511 G/C cg15704280 chr7:45808275 SEPT13 -1.0 -22.47 -0.77 2.54e-69 Height; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09669930 chr6:11233125 NEDD9 -0.43 -6.3 -0.32 9.14e-10 Hepatitis; LIHC cis rs6831352 0.879 rs67311928 chr4:100048999 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC trans rs11039100 1.000 rs11039101 chr11:5827080 A/G cg11650987 chr12:10280440 CLEC7A -0.4 -6.04 -0.31 4.1e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8141529 0.509 rs6005927 chr22:29255884 A/G cg02153584 chr22:29168773 CCDC117 0.53 7.84 0.39 5.65e-14 Lymphocyte counts; LIHC cis rs16828019 0.704 rs4996176 chr1:41488168 G/T cg03962019 chr1:41807865 NA 0.5 7.0 0.35 1.38e-11 Intelligence (multi-trait analysis); LIHC cis rs1823913 1.000 rs4853562 chr2:192118422 A/G cg12404831 chr2:192114017 MYO1B -0.33 -6.58 -0.34 1.75e-10 Obesity-related traits; LIHC cis rs240764 0.817 rs239190 chr6:101129067 C/T cg09795085 chr6:101329169 ASCC3 0.52 7.13 0.36 6.12e-12 Neuroticism; LIHC cis rs11676348 0.967 rs4674258 chr2:218990586 C/T cg00012203 chr2:219082015 ARPC2 -0.53 -7.26 -0.37 2.64e-12 Ulcerative colitis; LIHC cis rs11229555 0.645 rs4506677 chr11:58213852 T/C cg15696309 chr11:58395628 NA -0.65 -7.63 -0.38 2.37e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9926296 0.542 rs12599531 chr16:89909401 C/T cg04287289 chr16:89883240 FANCA -0.47 -7.29 -0.37 2.21e-12 Vitiligo; LIHC cis rs2832191 0.740 rs2832177 chr21:30478353 G/A cg08807101 chr21:30365312 RNF160 -0.78 -11.98 -0.54 7.44e-28 Dental caries; LIHC cis rs9372253 0.678 rs9487392 chr6:110708626 C/T cg01119278 chr6:110721349 DDO 0.31 6.6 0.34 1.57e-10 Platelet distribution width; LIHC cis rs9905704 0.624 rs8080071 chr17:57093825 C/T cg12560992 chr17:57184187 TRIM37 -0.66 -9.85 -0.47 2.49e-20 Testicular germ cell tumor; LIHC cis rs1904096 0.506 rs10034781 chr4:95169682 A/C cg11021082 chr4:95130006 SMARCAD1 0.5 9.32 0.45 1.48e-18 Type 2 diabetes; LIHC cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg11663144 chr21:46675770 NA -0.35 -6.48 -0.33 3.24e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg12310025 chr6:25882481 NA -0.64 -9.01 -0.44 1.54e-17 Blood metabolite levels; LIHC cis rs12477438 0.798 rs4622780 chr2:99631760 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.82 -10.47 -0.49 1.95e-22 Chronic sinus infection; LIHC cis rs6977660 0.941 rs4721825 chr7:19823427 A/C cg07541023 chr7:19748670 TWISTNB 0.37 5.83 0.3 1.27e-8 Thyroid stimulating hormone; LIHC cis rs2228479 0.557 rs34420680 chr16:89809171 C/T cg06558623 chr16:89946397 TCF25 0.87 11.97 0.54 7.87e-28 Skin colour saturation; LIHC trans rs4906332 1.000 rs1951389 chr14:103898525 G/C cg17675199 chr6:35436792 RPL10A 0.32 6.41 0.33 4.87e-10 Coronary artery disease; LIHC cis rs597539 0.616 rs513476 chr11:68698996 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.74 10.16 0.48 2.21e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs798554 0.610 rs2251491 chr7:2852835 T/C cg13628971 chr7:2884303 GNA12 0.43 6.74 0.34 6.82e-11 Height; LIHC cis rs7107174 1.000 rs4134379 chr11:77992588 A/G cg02023728 chr11:77925099 USP35 0.46 8.88 0.43 3.83e-17 Testicular germ cell tumor; LIHC cis rs9354352 0.791 rs4710306 chr6:66700271 A/G cg07460842 chr6:66804631 NA -0.6 -9.36 -0.45 1.1e-18 Initial pursuit acceleration in psychotic disorders; LIHC trans rs7927592 0.731 rs11228275 chr11:68303980 G/A cg00789545 chr14:102770909 RAGE 0.35 6.05 0.31 3.87e-9 Total body bone mineral density; LIHC cis rs12477438 0.501 rs7608938 chr2:99782226 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs72627123 0.867 rs61522544 chr14:74481953 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.53 0.46 2.97e-19 Morning vs. evening chronotype; LIHC cis rs7100689 0.577 rs1417219 chr10:82041409 C/T cg00277334 chr10:82204260 NA -0.53 -6.47 -0.33 3.37e-10 Post bronchodilator FEV1; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17967728 chr15:52263786 LEO1 -0.42 -6.06 -0.31 3.52e-9 Alopecia areata; LIHC cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg09222892 chr1:25734099 RHCE -0.46 -8.44 -0.42 9.17e-16 Erythrocyte sedimentation rate; LIHC cis rs1062177 1.000 rs2915880 chr5:151147334 G/A cg00977110 chr5:151150581 G3BP1 0.56 7.12 0.36 6.6e-12 Preschool internalizing problems; LIHC cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg07414643 chr4:187882934 NA 0.24 6.19 0.32 1.7e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2108225 0.934 rs2283044 chr7:107440553 A/G cg18560240 chr7:107437656 SLC26A3 0.41 6.63 0.34 1.35e-10 Ulcerative colitis; LIHC cis rs17376456 1.000 rs13181660 chr5:93533658 A/G cg25358565 chr5:93447407 FAM172A 1.04 9.46 0.46 5.21e-19 Diabetic retinopathy; LIHC cis rs2997447 0.601 rs61776580 chr1:26432719 C/T cg19633962 chr1:26362018 EXTL1 -0.63 -5.75 -0.3 1.96e-8 QRS complex (12-leadsum); LIHC cis rs595982 0.559 rs73061643 chr19:49368151 A/G cg21252483 chr19:49399788 TULP2 -0.92 -10.22 -0.48 1.4e-21 Red cell distribution width; LIHC cis rs7542091 0.704 rs9429825 chr1:210052133 C/G cg22029157 chr1:209979665 IRF6 0.37 6.07 0.31 3.43e-9 Monobrow; LIHC cis rs2279817 1.000 rs2279817 chr1:18021858 T/C cg21791023 chr1:18019539 ARHGEF10L -0.64 -8.28 -0.41 2.77e-15 Neuroticism; LIHC cis rs5753618 0.561 rs2413047 chr22:31666026 A/G cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00260888 chr20:30865478 KIF3B 0.5 6.82 0.35 4.11e-11 Lung function (FEV1/FVC); LIHC cis rs7635838 0.684 rs2606758 chr3:11353064 G/A cg00170343 chr3:11313890 ATG7 0.6 10.28 0.49 8.76e-22 HDL cholesterol; LIHC cis rs9359856 0.564 rs41273329 chr6:90393483 G/A cg13799429 chr6:90582589 CASP8AP2 -0.66 -6.23 -0.32 1.34e-9 Bipolar disorder; LIHC cis rs60871478 0.838 rs7789321 chr7:800977 A/G cg11064039 chr7:766100 PRKAR1B;HEATR2 0.51 5.71 0.3 2.41e-8 Cerebrospinal P-tau181p levels; LIHC cis rs2576037 0.796 rs2571033 chr18:44578552 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.21 -0.36 3.52e-12 Personality dimensions; LIHC cis rs250677 1.000 rs250676 chr5:148425518 A/T cg18129178 chr5:148520854 ABLIM3 -0.43 -7.03 -0.36 1.14e-11 Breast cancer; LIHC trans rs208515 0.525 rs4145045 chr6:66678949 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.75 8.71 0.43 1.36e-16 Exhaled nitric oxide levels; LIHC cis rs78456975 0.550 rs10197874 chr2:1545310 A/G cg01028140 chr2:1542097 TPO -0.45 -7.08 -0.36 8.24e-12 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs11640734 0.609 rs11647746 chr16:89806343 C/A cg06558623 chr16:89946397 TCF25 0.83 11.51 0.53 3.9e-26 Interleukin-17 levels; LIHC cis rs933688 0.938 rs7708782 chr5:90718517 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.61 0.67 7.88e-46 Smoking behavior; LIHC cis rs6062302 0.522 rs3787112 chr20:62222411 G/A cg06363034 chr20:62225388 GMEB2 -0.43 -7.33 -0.37 1.73e-12 Glioblastoma; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg00715988 chr14:96968640 PAPOLA -0.38 -6.4 -0.33 5.11e-10 Electroencephalogram traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00261252 chr4:79860706 PAQR3 -0.48 -6.8 -0.35 4.65e-11 Pancreatic cancer; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg23640757 chr6:7889014 TXNDC5 -0.38 -6.37 -0.33 6.1e-10 Pain; LIHC cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg09222892 chr1:25734099 RHCE -0.45 -8.27 -0.41 3e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs77637988 0.603 rs72820445 chr2:48607856 T/C cg00032884 chr2:48540671 FOXN2 0.4 6.19 0.32 1.68e-9 Joint mobility (Beighton score); LIHC cis rs9381040 0.655 rs4140578 chr6:41041829 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.43 -6.69 -0.34 8.96e-11 Alzheimer's disease (late onset); LIHC cis rs7188697 0.769 rs9932944 chr16:58616165 C/T cg02549819 chr16:58548995 SETD6 0.49 7.65 0.38 2e-13 QT interval; LIHC cis rs4975616 0.869 rs466502 chr5:1325767 C/T cg07493874 chr5:1342172 CLPTM1L 0.62 10.19 0.48 1.84e-21 Lung cancer; LIHC cis rs17102423 0.573 rs7144259 chr14:65537559 T/A cg11161011 chr14:65562177 MAX -0.42 -5.78 -0.3 1.69e-8 Obesity-related traits; LIHC trans rs4129059 1.000 rs61443257 chr1:214673211 G/A cg08187585 chr14:105393182 PLD4 -0.35 -6.77 -0.34 5.62e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11583043 0.874 rs11578366 chr1:101396852 T/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.3 0.32 8.96e-10 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7095944 0.614 rs61872084 chr10:126439062 C/T cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.87e-10 Asthma; LIHC cis rs8014671 0.546 rs12433355 chr14:70819717 T/C cg25576086 chr14:70833871 SYNJ2BP -0.54 -10.2 -0.48 1.6e-21 Prostate cancer; LIHC cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.26e-51 Menopause (age at onset); LIHC cis rs9790314 0.521 rs1450522 chr3:161077630 A/G cg03342759 chr3:160939853 NMD3 -0.57 -8.44 -0.42 8.91e-16 Morning vs. evening chronotype; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06467587 chr16:15808736 MYH11;NDE1 0.42 6.12 0.31 2.56e-9 Longevity; LIHC cis rs62458065 1.000 rs10246687 chr7:32465183 T/A cg06627557 chr7:32535165 LSM5;AVL9 -0.64 -7.32 -0.37 1.77e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs3806843 0.966 rs6579965 chr5:140168811 T/G cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.85e-26 Platelet count; LIHC cis rs208520 0.690 rs4710564 chr6:66823478 A/G cg07460842 chr6:66804631 NA 0.77 8.68 0.42 1.69e-16 Exhaled nitric oxide output; LIHC cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.685 rs4785568 chr16:89553707 A/G cg06640241 chr16:89574553 SPG7 0.85 15.92 0.65 4.43e-43 Multiple myeloma (IgH translocation); LIHC cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg03806693 chr22:41940476 POLR3H 1.06 12.64 0.56 2.63e-30 Vitiligo; LIHC cis rs4925386 0.840 rs6142738 chr20:60919960 C/T cg24112000 chr20:60950667 NA 0.44 5.87 0.3 1.05e-8 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs9473924 0.505 rs9473938 chr6:50874050 C/T cg14470998 chr6:50812995 TFAP2B 0.95 10.98 0.51 3.11e-24 Body mass index; LIHC cis rs11608355 0.545 rs2302706 chr12:109894028 A/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs16828019 0.929 rs8179465 chr1:41701747 C/T cg03962019 chr1:41807865 NA 0.51 7.42 0.37 9.28e-13 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.875 rs2748482 chr6:146336532 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.85 0.54 2.26e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs6963495 0.818 rs9769403 chr7:105163091 G/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs6426558 0.537 rs6685823 chr1:227270835 A/G cg10327440 chr1:227177885 CDC42BPA 0.44 6.82 0.35 4.03e-11 Neutrophil percentage of white cells; LIHC cis rs1670533 0.769 rs6814833 chr4:1057679 A/C cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg13047869 chr3:10149882 C3orf24 0.49 5.99 0.31 5.26e-9 Alzheimer's disease; LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.75 -0.3 1.94e-8 Total body bone mineral density; LIHC cis rs763014 0.966 rs4984903 chr16:680695 A/G cg00908189 chr16:619842 PIGQ 0.82 12.91 0.57 2.45e-31 Height; LIHC cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs74417235 0.673 rs6873342 chr5:154051835 A/G cg25588787 chr5:154027256 NA -0.4 -5.91 -0.3 8.33e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs34245846 0.704 rs11264278 chr1:154845534 G/C cg06418219 chr1:154948305 SHC1;CKS1B 0.88 12.76 0.57 8.76e-31 Atrial fibrillation; LIHC cis rs7613875 0.580 rs3774745 chr3:50204745 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.53 -7.93 -0.39 3.22e-14 Body mass index; LIHC cis rs7662987 0.517 rs1453873 chr4:100022571 T/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.3 0.49 7.38e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7116495 0.609 rs10898812 chr11:71698801 G/A cg07596299 chr11:71824057 C11orf51 -0.75 -5.72 -0.3 2.3e-8 Severe influenza A (H1N1) infection; LIHC trans rs2243480 0.803 rs160649 chr7:65543199 C/T cg10756647 chr7:56101905 PSPH 1.06 12.78 0.57 7.55e-31 Diabetic kidney disease; LIHC cis rs941873 0.868 rs10740497 chr10:81126380 T/C cg11057378 chr10:81107060 PPIF 0.38 6.23 0.32 1.38e-9 Height; LIHC cis rs17125944 0.505 rs74620173 chr14:53194068 G/T cg13660082 chr14:53194042 PSMC6 -0.44 -7.62 -0.38 2.58e-13 Alzheimer's disease (late onset); LIHC cis rs412000 0.554 rs2680700 chr17:56440542 G/T cg12560992 chr17:57184187 TRIM37 0.5 6.2 0.32 1.58e-9 Primary tooth development (time to first tooth eruption); LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg12629250 chr15:20149347 NA 0.38 6.05 0.31 3.77e-9 Electroencephalogram traits; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg07133347 chr1:107600762 PRMT6 -0.45 -6.88 -0.35 2.82e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.84 0.78 8.76e-71 Height; LIHC cis rs921968 0.565 rs7603709 chr2:219642601 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.46 -0.33 3.67e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2760061 0.784 rs708116 chr1:228198196 C/A cg01200585 chr1:228362443 C1orf69 0.4 6.09 0.31 3.07e-9 Diastolic blood pressure; LIHC cis rs5769765 0.773 rs7290751 chr22:50318312 T/C cg02269571 chr22:50332266 NA -0.66 -9.07 -0.44 9.22e-18 Schizophrenia; LIHC cis rs10751667 0.643 rs7942693 chr11:957832 G/A cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.09e-12 Alzheimer's disease (late onset); LIHC cis rs936229 0.813 rs1378938 chr15:75096443 T/C cg14664628 chr15:75095509 CSK -1.03 -21.44 -0.76 3.08e-65 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC trans rs875971 0.660 rs10281080 chr7:66042441 T/C cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC trans rs3780486 0.757 rs10813949 chr9:33123464 G/A cg04842962 chr6:43655489 MRPS18A 1.05 24.84 0.8 1.41e-78 IgG glycosylation; LIHC cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg07424592 chr7:64974309 NA 0.81 9.45 0.45 5.58e-19 Diabetic kidney disease; LIHC cis rs2439831 0.867 rs3213990 chr15:43670226 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.74 10.84 0.51 9.62e-24 Lung cancer in ever smokers; LIHC cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg00149659 chr3:10157352 C3orf10 0.61 6.7 0.34 8.75e-11 Alzheimer's disease; LIHC cis rs3749237 0.576 rs4241406 chr3:49600426 C/T cg07636037 chr3:49044803 WDR6 0.52 7.96 0.4 2.62e-14 Resting heart rate; LIHC cis rs7116495 1.000 rs17161966 chr11:71815308 T/C cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs11779988 0.545 rs431961 chr8:17786204 T/G cg01800426 chr8:17659068 MTUS1 -0.4 -5.85 -0.3 1.16e-8 Breast cancer; LIHC cis rs7223966 1.000 rs992416 chr17:61745905 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.57 0.33 1.83e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1559088 0.947 rs7259879 chr19:33549462 T/C cg17764715 chr19:33622953 WDR88 0.41 5.75 0.3 2.03e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs11711311 1.000 rs34475696 chr3:113458293 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.05 -0.36 9.75e-12 IgG glycosylation; LIHC cis rs8081395 0.737 rs4968401 chr17:58040730 T/C cg13753209 chr17:57696993 CLTC -0.39 -5.92 -0.3 7.98e-9 White blood cell count; LIHC cis rs6783573 0.711 rs3806701 chr3:46617337 G/A cg21489266 chr3:46619131 LRRC2;TDGF1 -0.45 -6.77 -0.34 5.46e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs6547741 0.844 rs9678851 chr2:27887034 C/A cg27432699 chr2:27873401 GPN1 -0.93 -16.39 -0.66 5.96e-45 Oral cavity cancer; LIHC cis rs10792665 0.512 rs6592087 chr11:82595975 A/T cg24227371 chr11:82718527 RAB30 -0.28 -6.82 -0.35 4.17e-11 Obesity-related traits; LIHC cis rs738322 0.533 rs2284064 chr22:38547395 A/C cg25457927 chr22:38595422 NA -0.37 -8.88 -0.43 3.92e-17 Cutaneous nevi; LIHC cis rs4481887 0.512 rs1538702 chr1:248519665 A/G cg07483650 chr1:248525007 OR2T4 0.44 7.84 0.39 5.94e-14 Common traits (Other); LIHC cis rs6424115 1.000 rs4237 chr1:24114129 C/T cg15997130 chr1:24165203 NA 0.38 7.62 0.38 2.47e-13 Immature fraction of reticulocytes; LIHC trans rs1499614 1.000 rs2707838 chr7:66159201 C/T cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg02290350 chr8:58132656 NA 0.51 10.45 0.49 2.28e-22 Developmental language disorder (linguistic errors); LIHC cis rs1707322 0.721 rs10430123 chr1:46221440 T/C cg06784218 chr1:46089804 CCDC17 0.42 7.67 0.38 1.79e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9612 1.000 rs28373139 chr19:44246706 A/G cg08581076 chr19:44259116 C19orf61 0.66 8.43 0.41 9.65e-16 Exhaled nitric oxide output; LIHC cis rs7296418 0.922 rs1790134 chr12:123697898 T/C cg05973401 chr12:123451056 ABCB9 0.42 6.13 0.31 2.44e-9 Platelet count; LIHC cis rs1559088 0.803 rs10411529 chr19:33616256 A/C cg27124370 chr19:33622961 WDR88 0.53 8.53 0.42 4.71e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4555082 0.874 rs78923231 chr14:105754033 C/T cg13114125 chr14:105738426 BRF1 -0.79 -10.06 -0.48 5.05e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs6939532 0.544 rs10946816 chr6:26361946 C/G cg14345882 chr6:26364793 BTN3A2 0.39 5.76 0.3 1.88e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg20295408 chr7:1910781 MAD1L1 -0.48 -6.93 -0.35 2.08e-11 Bipolar disorder and schizophrenia; LIHC cis rs7520050 0.966 rs7515491 chr1:46355079 A/G cg03146154 chr1:46216737 IPP -0.37 -5.91 -0.3 8.14e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg08280861 chr8:58055591 NA 0.53 6.42 0.33 4.45e-10 Developmental language disorder (linguistic errors); LIHC cis rs509477 1.000 rs7240845 chr18:32574960 G/C cg23791764 chr18:32556832 MAPRE2 -0.49 -6.7 -0.34 8.58e-11 Cerebrospinal fluid AB1-42 levels; LIHC cis rs992157 0.560 rs6436048 chr2:219109033 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.75 12.3 0.55 4.82e-29 Colorectal cancer; LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg13126279 chr21:47581558 C21orf56 0.46 7.71 0.38 1.36e-13 Testicular germ cell tumor; LIHC cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.08e-11 Alzheimer's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01739569 chr14:31091426 SCFD1 -0.47 -6.04 -0.31 3.97e-9 Systolic blood pressure; LIHC cis rs2153535 0.580 rs9406163 chr6:8466642 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7662987 0.517 rs1453874 chr4:100022724 G/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs2295359 0.892 rs4655686 chr1:67638004 T/A cg12940439 chr1:67600707 NA 0.35 6.2 0.32 1.63e-9 Psoriasis; LIHC cis rs11690935 1.000 rs312925 chr2:172563922 G/A cg13550731 chr2:172543902 DYNC1I2 -0.92 -18.0 -0.7 2e-51 Schizophrenia; LIHC cis rs12594515 1.000 rs8033148 chr15:45997929 G/A cg06207120 chr15:45996521 NA 0.31 5.83 0.3 1.27e-8 Waist circumference;Weight; LIHC cis rs7618915 1.000 rs7618915 chr3:52279594 G/A cg18404041 chr3:52824283 ITIH1 -0.38 -5.76 -0.3 1.91e-8 Bipolar disorder; LIHC cis rs28595532 0.800 rs114321375 chr4:119341663 G/A cg21605333 chr4:119757512 SEC24D 1.07 8.66 0.42 1.91e-16 Cannabis dependence symptom count; LIHC cis rs7258015 1.000 rs3176768 chr19:10449665 A/G cg13981319 chr19:10446556 ICAM3 -0.44 -6.91 -0.35 2.33e-11 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs6088590 1.000 rs12626122 chr20:33425800 A/G cg24642439 chr20:33292090 TP53INP2 0.82 11.11 0.51 1.09e-24 Coronary artery disease; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg03721293 chr16:90014378 DEF8 0.42 7.0 0.35 1.34e-11 Skin colour saturation; LIHC cis rs798554 0.686 rs2644298 chr7:2858448 G/C cg19717773 chr7:2847554 GNA12 -0.42 -7.55 -0.38 3.95e-13 Height; LIHC cis rs7772486 0.754 rs6922507 chr6:146250155 A/T cg05347473 chr6:146136440 FBXO30 -0.39 -6.13 -0.31 2.38e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13633754 chr9:95858523 C9orf89 -0.41 -6.32 -0.32 7.96e-10 Pancreatic cancer; LIHC cis rs589448 0.902 rs315113 chr12:69786543 G/T cg19645103 chr12:69753606 YEATS4 0.4 6.04 0.31 3.98e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2834188 0.961 rs8130807 chr21:34690013 A/G cg14352951 chr21:34696688 IFNAR1 0.47 6.53 0.33 2.35e-10 Narcolepsy; LIHC cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg08219700 chr8:58056026 NA 0.51 6.7 0.34 8.62e-11 Developmental language disorder (linguistic errors); LIHC cis rs9911578 1.000 rs304296 chr17:56834229 G/T cg05425664 chr17:57184151 TRIM37 -0.58 -8.69 -0.43 1.55e-16 Intelligence (multi-trait analysis); LIHC cis rs7917772 0.560 rs7912339 chr10:104373758 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.24e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1215050 0.791 rs1025201 chr4:98902938 A/G cg05340658 chr4:99064831 C4orf37 -0.39 -5.8 -0.3 1.54e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs12497850 0.931 rs9311430 chr3:48845251 C/T cg07636037 chr3:49044803 WDR6 0.93 16.94 0.68 3.74e-47 Parkinson's disease; LIHC cis rs11229555 1.000 rs10896795 chr11:58366561 A/G cg15696309 chr11:58395628 NA -0.74 -9.01 -0.44 1.44e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 0.964 rs6945019 chr7:65922458 C/G cg11764359 chr7:65958608 NA 0.88 15.54 0.64 1.41e-41 Aortic root size; LIHC cis rs10751667 0.857 rs6597952 chr11:991109 C/G cg10932868 chr11:921992 NA 0.34 6.32 0.32 8.33e-10 Alzheimer's disease (late onset); LIHC cis rs9916302 0.851 rs11870631 chr17:37645129 C/T cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC trans rs35110281 0.632 rs9306160 chr21:45107562 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.47 6.26 0.32 1.17e-9 Mean corpuscular volume; LIHC cis rs12477438 0.520 rs6712704 chr2:99719687 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.68 0.78 3.75e-70 Chronic sinus infection; LIHC trans rs10038113 0.530 rs7445227 chr5:26024457 T/G cg05807885 chr1:204183355 GOLT1A 0.32 6.36 0.33 6.51e-10 Autism; LIHC cis rs5758511 0.637 rs5751244 chr22:42617411 T/C cg00645731 chr22:42541494 CYP2D7P1 0.53 8.44 0.42 9.3e-16 Birth weight; LIHC cis rs2153535 0.580 rs1335636 chr6:8465047 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs13191362 0.935 rs4273664 chr6:162955494 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.71 6.12 0.31 2.56e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg10411590 chr13:21900810 NA 0.42 6.83 0.35 3.88e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs763121 0.853 rs6001173 chr22:39015302 A/G cg06022373 chr22:39101656 GTPBP1 0.75 14.87 0.63 6.62e-39 Menopause (age at onset); LIHC trans rs4718428 0.705 rs4717328 chr7:66352665 T/C cg10756647 chr7:56101905 PSPH 0.63 8.62 0.42 2.51e-16 Corneal structure; LIHC cis rs6570726 0.791 rs11155435 chr6:145938545 T/C cg23711669 chr6:146136114 FBXO30 0.74 12.47 0.56 1.14e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs1400745 0.718 rs1200414 chr14:35330893 G/A cg05294307 chr14:35346193 BAZ1A -0.45 -7.54 -0.38 4.33e-13 Monocyte count; LIHC cis rs2573652 0.674 rs11630619 chr15:100543367 G/A cg09918751 chr15:100517450 ADAMTS17 -0.69 -11.98 -0.54 7.7e-28 Height; LIHC cis rs8072100 0.817 rs9892497 chr17:45545919 G/A cg08085267 chr17:45401833 C17orf57 -0.44 -6.47 -0.33 3.43e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6831352 0.851 rs1230164 chr4:99986023 C/G cg12011299 chr4:100065546 ADH4 0.56 9.7 0.46 7.96e-20 Alcohol dependence; LIHC cis rs9303280 0.806 rs9907088 chr17:38035116 G/A cg11212589 chr17:38028394 ZPBP2 0.35 7.09 0.36 7.92e-12 Self-reported allergy; LIHC cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg03264133 chr6:25882463 NA 0.68 8.9 0.43 3.33e-17 Intelligence (multi-trait analysis); LIHC cis rs6840360 0.593 rs1877186 chr4:152692418 C/G cg22705602 chr4:152727874 NA -0.4 -8.48 -0.42 6.71e-16 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.528 rs111682961 chr2:136653848 C/T cg07169764 chr2:136633963 MCM6 1.31 21.37 0.76 6.13e-65 Corneal structure; LIHC cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg08067268 chr2:26466485 HADHB;HADHA 0.49 6.36 0.33 6.31e-10 Gut microbiome composition (summer); LIHC cis rs1348850 0.958 rs11689550 chr2:178456298 A/G cg27490568 chr2:178487706 NA 0.37 5.82 0.3 1.34e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1008375 1.000 rs1121089 chr4:17676476 C/A cg02297831 chr4:17616191 MED28 0.41 6.47 0.33 3.44e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs79149102 0.579 rs6495142 chr15:75320166 C/T cg17294928 chr15:75287854 SCAMP5 -0.48 -6.2 -0.32 1.61e-9 Lung cancer; LIHC trans rs1814175 0.645 rs1851845 chr11:49982396 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.25e-12 Bipolar disorder; LIHC trans rs6489882 0.867 rs2384072 chr12:113367422 T/C cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg14004847 chr7:1930337 MAD1L1 -0.62 -9.44 -0.45 6.11e-19 Bipolar disorder and schizophrenia; LIHC cis rs709400 0.628 rs7146506 chr14:103924477 A/G cg26031613 chr14:104095156 KLC1 0.72 9.65 0.46 1.21e-19 Body mass index; LIHC cis rs9291683 0.588 rs3796829 chr4:10019138 C/G cg11266682 chr4:10021025 SLC2A9 0.33 7.15 0.36 5.29e-12 Bone mineral density; LIHC cis rs17433710 0.543 rs4233392 chr1:162645571 T/C cg01063088 chr1:162760584 HSD17B7 0.44 6.09 0.31 3.11e-9 Dupuytren's disease; LIHC cis rs4478858 0.709 rs937786 chr1:31857869 G/A cg00250761 chr1:31883323 NA 0.3 7.27 0.37 2.44e-12 Alcohol dependence; LIHC cis rs10744422 0.920 rs897393 chr12:123312051 A/G cg22842854 chr12:123319900 HIP1R 0.64 8.45 0.42 8.3e-16 Schizophrenia; LIHC cis rs1003719 0.715 rs2835613 chr21:38496883 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.77 -12.01 -0.54 5.58e-28 Eye color traits; LIHC cis rs17685 0.753 rs6951943 chr7:75772452 A/G cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1914816 1.000 rs2255408 chr15:76503295 G/T cg03037974 chr15:76606532 NA 0.6 6.14 0.31 2.32e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs7927592 0.763 rs624003 chr11:68231240 C/T cg16797656 chr11:68205561 LRP5 0.53 9.48 0.46 4.43e-19 Total body bone mineral density; LIHC cis rs2795502 1.000 rs2795502 chr10:43340662 G/A cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs10489202 0.634 rs11582396 chr1:168077636 C/T cg17859187 chr1:168147929 TIPRL 0.41 5.72 0.3 2.27e-8 Schizophrenia; LIHC trans rs1814175 0.645 rs1874969 chr11:49826700 G/A cg03929089 chr4:120376271 NA -0.84 -15.87 -0.65 6.88e-43 Height; LIHC trans rs7613875 0.580 rs11709503 chr3:49991167 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.42 6.2 0.32 1.66e-9 Body mass index; LIHC cis rs2010672 0.500 rs11631439 chr15:91143805 C/A cg26821196 chr15:91095069 CRTC3 0.32 5.99 0.31 5.4e-9 Sum eosinophil basophil counts;Eosinophil percentage of white cells;Eosinophil counts; LIHC cis rs12711979 0.729 rs6714956 chr2:3820454 T/C cg17052675 chr2:3827356 NA -0.42 -7.23 -0.36 3.22e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs2050392 0.928 rs6481677 chr10:30701816 A/G cg25182066 chr10:30743637 MAP3K8 -0.46 -7.36 -0.37 1.4e-12 Inflammatory bowel disease; LIHC cis rs9790314 0.871 rs466626 chr3:161103629 A/C cg03342759 chr3:160939853 NMD3 -0.65 -7.96 -0.4 2.49e-14 Morning vs. evening chronotype; LIHC cis rs9682041 0.660 rs34158232 chr3:170115360 T/C cg11886554 chr3:170076028 SKIL 0.63 5.84 0.3 1.21e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs6546550 0.901 rs6546559 chr2:70145833 G/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.61 -0.38 2.69e-13 Prevalent atrial fibrillation; LIHC trans rs877282 0.842 rs12357963 chr10:757562 C/T cg22713356 chr15:30763199 NA 1.42 12.22 0.55 9.43e-29 Uric acid levels; LIHC cis rs9733 0.596 rs11582840 chr1:150688487 A/G cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs8084351 0.517 rs7505888 chr18:50565946 T/C cg24270629 chr18:50823537 DCC 0.41 6.22 0.32 1.44e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7607369 0.596 rs10165754 chr2:219287370 A/G cg02176678 chr2:219576539 TTLL4 -0.51 -6.85 -0.35 3.44e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7534824 0.543 rs6693339 chr1:101424431 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.67 -7.64 -0.38 2.13e-13 Refractive astigmatism; LIHC cis rs9902453 0.899 rs1979572 chr17:28511978 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.84 0.43 4.98e-17 Coffee consumption (cups per day); LIHC cis rs7945718 0.781 rs10741604 chr11:12840940 C/A cg25843174 chr11:12811716 TEAD1 0.29 6.68 0.34 9.63e-11 Educational attainment (years of education); LIHC cis rs8141529 0.732 rs2239815 chr22:29192670 C/T cg15103426 chr22:29168792 CCDC117 -0.67 -11.66 -0.53 1.13e-26 Lymphocyte counts; LIHC cis rs4665809 1.000 rs1550382 chr2:26266877 T/G cg27170947 chr2:26402098 FAM59B -0.68 -8.33 -0.41 1.97e-15 Gut microbiome composition (summer); LIHC cis rs6912958 0.781 rs9444522 chr6:88309705 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.72 -0.39 1.33e-13 Monocyte percentage of white cells; LIHC cis rs4073582 0.595 rs9326370 chr11:65992008 A/G cg16950941 chr11:66035639 RAB1B 0.51 8.22 0.41 4.35e-15 Gout; LIHC cis rs6088590 0.648 rs6058105 chr20:33271719 C/T cg24642439 chr20:33292090 TP53INP2 0.45 6.28 0.32 1.01e-9 Coronary artery disease; LIHC cis rs1580019 0.844 rs1376290 chr7:32486922 C/T cg07520158 chr7:32535189 LSM5;AVL9 0.51 6.88 0.35 2.86e-11 Cognitive ability; LIHC cis rs9640161 0.659 rs7781827 chr7:150008858 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.41 -0.41 1.12e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs1816752 0.905 rs7995909 chr13:25013297 T/C cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs2559856 1.000 rs2695285 chr12:102089043 G/A cg12924262 chr12:102091054 CHPT1 0.53 8.56 0.42 3.89e-16 Blood protein levels; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg15181151 chr6:150070149 PCMT1 0.4 6.59 0.34 1.71e-10 Lung cancer; LIHC cis rs9733 0.596 rs11586422 chr1:150679358 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs7246657 0.943 rs6508711 chr19:37815134 G/T cg23950597 chr19:37808831 NA -0.45 -6.02 -0.31 4.48e-9 Coronary artery calcification; LIHC cis rs2204008 0.640 rs11520199 chr12:38211026 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs7100689 0.615 rs10788639 chr10:82233225 C/G cg00277334 chr10:82204260 NA -0.44 -6.01 -0.31 4.77e-9 Post bronchodilator FEV1; LIHC cis rs2832191 0.935 rs67287920 chr21:30523519 C/A cg24692254 chr21:30365293 RNF160 -0.5 -8.63 -0.42 2.42e-16 Dental caries; LIHC trans rs4924935 0.509 rs28540773 chr17:18761754 T/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.8e-10 Pancreatic cancer; LIHC cis rs4919087 0.748 rs701817 chr10:98977329 G/C cg25902810 chr10:99078978 FRAT1 -0.56 -6.44 -0.33 4.08e-10 Monocyte count; LIHC cis rs2239547 0.521 rs9682464 chr3:52888485 C/T cg11645453 chr3:52864694 ITIH4 0.36 9.4 0.45 7.99e-19 Schizophrenia; LIHC cis rs7172677 0.768 rs72730587 chr15:75358053 A/G cg17294928 chr15:75287854 SCAMP5 0.43 6.19 0.32 1.69e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7582180 0.663 rs2053263 chr2:100971407 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.19 0.4 5.25e-15 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs2808586 chr1:231515559 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs2439831 0.764 rs12324584 chr15:43683446 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.87 15.69 0.65 3.53e-42 Lung cancer in ever smokers; LIHC cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7412746 0.658 rs72704682 chr1:150897677 A/T cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC trans rs61931739 0.517 rs56308002 chr12:34016021 C/G cg26384229 chr12:38710491 ALG10B 0.52 7.2 0.36 3.74e-12 Morning vs. evening chronotype; LIHC cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg18252515 chr7:66147081 NA 1.21 15.73 0.65 2.39e-42 Diabetic kidney disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17765461 chr19:1408416 DAZAP1 -0.45 -6.58 -0.34 1.75e-10 Calcium levels; LIHC cis rs9443189 0.762 rs1321162 chr6:76456347 C/T cg01950844 chr6:76311363 SENP6 0.52 6.6 0.34 1.57e-10 Prostate cancer; LIHC cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg13397359 chr6:42928475 GNMT -0.73 -10.66 -0.5 4.25e-23 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2842992 0.830 rs2842974 chr6:160159034 C/T cg11366901 chr6:160182831 ACAT2 0.93 15.81 0.65 1.21e-42 Age-related macular degeneration (geographic atrophy); LIHC cis rs35110281 0.720 rs162392 chr21:44941406 A/G cg04455712 chr21:45112962 RRP1B 0.46 7.47 0.37 6.82e-13 Mean corpuscular volume; LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg20607798 chr8:58055168 NA 0.62 7.91 0.39 3.52e-14 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg17372223 chr3:52568218 NT5DC2 0.37 5.74 0.3 2.04e-8 Bipolar disorder; LIHC cis rs240764 0.658 rs7451736 chr6:101189901 C/T cg12253828 chr6:101329408 ASCC3 -0.39 -5.95 -0.31 6.78e-9 Neuroticism; LIHC cis rs61677309 1.000 rs55899310 chr11:118158702 T/C cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs7945705 0.902 rs7930026 chr11:9013639 T/C cg12365402 chr11:9010492 NRIP3 0.32 7.84 0.39 5.97e-14 Hemoglobin concentration; LIHC cis rs8078723 0.510 rs3087852 chr17:38137364 G/A cg17467752 chr17:38218738 THRA -0.56 -9.58 -0.46 2.08e-19 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6445975 0.619 rs112015230 chr3:58262204 T/C cg23715586 chr3:58305044 RPP14 -0.37 -6.2 -0.32 1.65e-9 Systemic lupus erythematosus; LIHC cis rs9733 0.596 rs72700897 chr1:150626038 C/G cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs929354 0.713 rs1034785 chr7:157002383 T/C cg17757837 chr7:157058334 UBE3C 0.73 11.89 0.54 1.57e-27 Body mass index; LIHC cis rs4908768 0.906 rs12403339 chr1:8558292 G/A cg25722041 chr1:8623473 RERE 0.41 5.85 0.3 1.18e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9368481 0.546 rs12664610 chr6:26885031 G/A cg12292205 chr6:26970375 C6orf41 0.43 7.08 0.36 8.36e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs6665290 0.901 rs7535826 chr1:227213968 A/C cg10327440 chr1:227177885 CDC42BPA 1.08 21.35 0.76 7.34e-65 Myeloid white cell count; LIHC cis rs6840360 0.571 rs7674244 chr4:152488302 T/C cg22705602 chr4:152727874 NA -0.33 -6.49 -0.33 2.93e-10 Intelligence (multi-trait analysis); LIHC cis rs16870629 0.541 rs2334955 chr5:1062444 A/G cg18655438 chr5:1077845 SLC12A7 -0.35 -5.74 -0.3 2.14e-8 QT interval; LIHC cis rs10911232 0.507 rs10797822 chr1:183017769 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.49 0.49 1.7e-22 Hypertriglyceridemia; LIHC cis rs7568458 0.709 rs2028898 chr2:85777270 G/A cg02493740 chr2:85810744 VAMP5 -0.48 -7.97 -0.4 2.43e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg21280719 chr6:42927975 GNMT 0.35 7.7 0.38 1.44e-13 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2404602 0.692 rs12913810 chr15:77166675 T/C cg23625390 chr15:77176239 SCAPER 0.35 5.81 0.3 1.43e-8 Blood metabolite levels; LIHC cis rs477895 0.838 rs1058735 chr11:64000410 C/G cg04317338 chr11:64019027 PLCB3 0.86 10.59 0.5 7.21e-23 Mean platelet volume; LIHC cis rs7959452 0.557 rs899224 chr12:69784774 A/G cg20891283 chr12:69753455 YEATS4 0.9 19.55 0.73 1.18e-57 Blood protein levels; LIHC cis rs12220238 1.000 rs7907801 chr10:75976638 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.62 6.12 0.31 2.54e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2580764 0.598 rs2580772 chr2:55218805 G/T cg09592903 chr2:55203963 RTN4 0.71 13.11 0.58 4.35e-32 Mean platelet volume; LIHC cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.12e-8 Bipolar disorder; LIHC trans rs35213789 0.887 rs210603 chr7:69236235 C/T cg11912179 chr11:134026542 NCAPD3 -0.39 -7.01 -0.35 1.27e-11 Childhood ear infection; LIHC cis rs11673344 0.764 rs826303 chr19:37442451 C/A cg27390819 chr19:37464633 NA -0.53 -6.42 -0.33 4.52e-10 Obesity-related traits; LIHC cis rs11098499 0.954 rs71629403 chr4:120372567 C/T cg09307838 chr4:120376055 NA 0.77 12.14 0.55 1.93e-28 Corneal astigmatism; LIHC cis rs7829975 0.533 rs1039917 chr8:8718850 C/T cg06636001 chr8:8085503 FLJ10661 0.33 5.72 0.3 2.37e-8 Mood instability; LIHC cis rs7224685 0.906 rs2278524 chr17:4081975 A/G cg09695851 chr17:3907499 NA -0.57 -8.18 -0.4 5.65e-15 Type 2 diabetes; LIHC cis rs875971 0.660 rs3857686 chr7:66036191 C/T cg18876405 chr7:65276391 NA -0.44 -7.7 -0.38 1.44e-13 Aortic root size; LIHC cis rs9393692 0.905 rs1124999 chr6:26287043 G/T cg13736514 chr6:26305472 NA -0.38 -6.39 -0.33 5.53e-10 Educational attainment; LIHC cis rs801193 1.000 rs7788576 chr7:66148302 G/A cg14393609 chr7:65229607 NA -0.38 -5.87 -0.3 1.02e-8 Aortic root size; LIHC cis rs1843834 0.858 rs4674933 chr2:225514923 C/T cg22509189 chr2:225307070 NA -0.63 -7.57 -0.38 3.54e-13 IgE levels in asthmatics (D.p. specific); LIHC cis rs2963155 0.518 rs853184 chr5:142640901 C/T cg17617527 chr5:142782415 NR3C1 0.94 10.62 0.5 5.85e-23 Breast cancer; LIHC cis rs1552244 0.882 rs66559400 chr3:10012551 G/A cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs11758351 0.660 rs11753131 chr6:26219384 G/A cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs477895 0.838 rs11607007 chr11:64007976 C/T cg04317338 chr11:64019027 PLCB3 0.85 10.23 0.48 1.34e-21 Mean platelet volume; LIHC cis rs7707921 0.690 rs6870335 chr5:81590070 A/T cg15871215 chr5:81402204 ATG10 -0.68 -8.24 -0.41 3.82e-15 Breast cancer; LIHC cis rs4917833 0.752 rs4598598 chr10:100216817 C/T cg19043522 chr10:100227446 HPSE2 0.41 5.85 0.3 1.14e-8 Pediatric bone mineral density (femoral neck); LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg05064044 chr6:292385 DUSP22 -0.58 -8.12 -0.4 8.67e-15 Menopause (age at onset); LIHC cis rs9457247 1.000 rs439237 chr6:167391392 A/G cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs2153535 0.541 rs9505456 chr6:8479001 T/C cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs12497850 0.931 rs62262517 chr3:49134914 T/G cg06212747 chr3:49208901 KLHDC8B 0.6 7.65 0.38 2.05e-13 Parkinson's disease; LIHC cis rs9486719 0.947 rs12208556 chr6:96903486 C/T cg06623918 chr6:96969491 KIAA0776 -0.66 -7.5 -0.38 5.58e-13 Migraine;Coronary artery disease; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg24859375 chr12:7121914 LPCAT3 0.41 6.18 0.32 1.85e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1552244 0.688 rs7645137 chr3:10020549 A/AT cg08888203 chr3:10149979 C3orf24 0.49 6.12 0.31 2.53e-9 Alzheimer's disease; LIHC cis rs1443512 0.704 rs4759308 chr12:54329031 A/T cg12374095 chr12:54320830 NA 0.44 6.43 0.33 4.26e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.09 -0.44 8.23e-18 Bipolar disorder; LIHC cis rs116095464 0.558 rs9312979 chr5:222057 A/C cg22496380 chr5:211416 CCDC127 -1.15 -10.21 -0.48 1.54e-21 Breast cancer; LIHC cis rs16828019 0.852 rs3820090 chr1:41573652 A/G cg03962019 chr1:41807865 NA 0.49 7.08 0.36 8.11e-12 Intelligence (multi-trait analysis); LIHC cis rs10848704 0.525 rs4073984 chr12:2885780 G/A cg19995117 chr12:2880862 NA 0.33 6.07 0.31 3.47e-9 Quantitative traits; LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg04013166 chr16:89971882 TCF25 0.61 8.56 0.42 3.94e-16 Skin colour saturation; LIHC cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg15691649 chr6:25882328 NA -0.51 -7.33 -0.37 1.65e-12 Blood metabolite levels; LIHC cis rs1997103 1.000 rs6949222 chr7:55411264 C/T cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs17376456 1.000 rs34068652 chr5:93563319 G/A cg25358565 chr5:93447407 FAM172A 1.05 9.72 0.47 7.24e-20 Diabetic retinopathy; LIHC cis rs10911251 0.528 rs10911255 chr1:183088868 G/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Colorectal cancer; LIHC cis rs16828019 0.852 rs12742803 chr1:41648131 G/A cg20697417 chr1:41786797 NA 0.35 6.65 0.34 1.15e-10 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.715 rs11040586 chr11:49858432 T/A cg18944383 chr4:111397179 ENPEP 0.27 7.16 0.36 5.01e-12 Height; LIHC cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg07092213 chr7:1199455 ZFAND2A -0.42 -6.27 -0.32 1.07e-9 Longevity;Endometriosis; LIHC cis rs11229555 0.645 rs12272911 chr11:58183839 G/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06536200 chr11:44117561 EXT2 0.43 6.19 0.32 1.74e-9 Lung function (FEV1/FVC); LIHC cis rs9918079 0.506 rs7696127 chr4:15642953 T/A cg21123203 chr4:15471301 CC2D2A -0.45 -7.26 -0.37 2.6e-12 Obesity-related traits; LIHC cis rs9902453 0.808 rs76515799 chr17:28169491 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.98 0.54 7.79e-28 Coffee consumption (cups per day); LIHC cis rs138880 0.542 rs9616393 chr22:50314809 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.82 7.51 0.38 5.33e-13 Schizophrenia; LIHC cis rs7552404 0.727 rs7547056 chr1:76279267 C/T cg10523679 chr1:76189770 ACADM 0.59 7.36 0.37 1.38e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2842992 0.915 rs2758321 chr6:160071611 C/G cg16489826 chr6:160211363 TCP1;MRPL18 0.46 7.62 0.38 2.48e-13 Age-related macular degeneration (geographic atrophy); LIHC cis rs903552 0.800 rs6598478 chr15:102001696 A/T cg06707286 chr15:102010195 PCSK6 -0.44 -5.97 -0.31 5.84e-9 Diabetic kidney disease; LIHC cis rs8072100 0.935 rs78551919 chr17:45626002 A/C cg19378624 chr17:45501242 LOC100272146;C17orf57 0.36 5.71 0.3 2.39e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4908768 0.906 rs2144463 chr1:8583293 C/A cg25722041 chr1:8623473 RERE 0.41 5.81 0.3 1.45e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs34779708 0.931 rs4934709 chr10:35339324 A/C cg03585969 chr10:35415529 CREM -0.79 -11.8 -0.54 3.34e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs35110281 0.600 rs11089092 chr21:45120994 A/C cg04455712 chr21:45112962 RRP1B 0.47 8.05 0.4 1.42e-14 Mean corpuscular volume; LIHC cis rs7212590 0.748 rs8073489 chr17:57861794 A/C cg10252138 chr17:58120427 NA -0.61 -6.21 -0.32 1.5e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs1799949 1.000 rs2298862 chr17:41176688 T/C cg05368731 chr17:41323189 NBR1 0.74 12.61 0.56 3.38e-30 Menopause (age at onset); LIHC cis rs3106136 0.934 rs34145031 chr4:95167123 A/G cg11021082 chr4:95130006 SMARCAD1 -0.45 -8.14 -0.4 7.63e-15 Capecitabine sensitivity; LIHC cis rs174601 0.684 rs174528 chr11:61543499 T/C cg27386326 chr11:61587980 NA 0.63 12.92 0.57 2.17e-31 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC trans rs6600671 1.000 rs11249350 chr1:121178446 C/T cg09829573 chr1:144692074 NBPF9 -0.45 -8.09 -0.4 1.05e-14 Hip geometry; LIHC cis rs2795502 1.000 rs2473119 chr10:43339038 A/T cg20628663 chr10:43360327 NA -0.47 -7.32 -0.37 1.76e-12 Blood protein levels; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.53 0.53 3.28e-26 Prudent dietary pattern; LIHC cis rs9640161 0.742 rs2108853 chr7:150017589 A/C cg17279839 chr7:150038598 RARRES2 0.5 10.64 0.5 4.85e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs10751667 0.961 rs10794358 chr11:985547 C/T ch.11.42038R chr11:967971 AP2A2 0.6 11.05 0.51 1.79e-24 Alzheimer's disease (late onset); LIHC cis rs8078723 0.701 rs2305482 chr17:38140927 A/C cg17467752 chr17:38218738 THRA -0.58 -9.95 -0.47 1.17e-20 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs12701220 0.901 rs12701708 chr7:1090333 C/T cg16145915 chr7:1198662 ZFAND2A -0.31 -6.22 -0.32 1.46e-9 Bronchopulmonary dysplasia; LIHC cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg02290350 chr8:58132656 NA 0.48 9.92 0.47 1.54e-20 Developmental language disorder (linguistic errors); LIHC cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg18404041 chr3:52824283 ITIH1 0.49 8.1 0.4 9.6e-15 Electroencephalogram traits; LIHC cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.08 0.31 3.29e-9 Menopause (age at onset); LIHC trans rs9951602 0.512 rs8089247 chr18:76651467 C/A cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC cis rs875971 0.540 rs736270 chr7:65428822 T/C cg18876405 chr7:65276391 NA 0.56 9.41 0.45 7.27e-19 Aortic root size; LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs9814567 1.000 rs9814567 chr3:134218557 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.93 0.31 7.39e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9811920 0.514 rs1287283 chr3:99515750 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.47 6.54 0.33 2.3e-10 Axial length; LIHC cis rs1005277 0.579 rs1740742 chr10:38518860 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs6977660 1.000 rs6974669 chr7:19793296 T/A cg07541023 chr7:19748670 TWISTNB 0.41 6.26 0.32 1.15e-9 Thyroid stimulating hormone; LIHC cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg05527609 chr1:210001259 C1orf107 0.43 6.34 0.32 7.38e-10 Cleft lip with or without cleft palate; LIHC cis rs9640161 0.830 rs3757424 chr7:150067679 C/A cg17279839 chr7:150038598 RARRES2 0.38 7.77 0.39 9.54e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs752092 0.894 rs8042989 chr15:101770761 T/A cg25114630 chr15:101792522 CHSY1 0.55 6.88 0.35 2.78e-11 Corneal structure; LIHC cis rs2070488 0.965 rs2051215 chr3:38560345 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.86 -14.48 -0.62 2.26e-37 Electrocardiographic conduction measures; LIHC cis rs2274273 0.624 rs10143136 chr14:55743528 G/A cg01864836 chr14:55583639 NA -0.36 -5.85 -0.3 1.15e-8 Protein biomarker; LIHC cis rs7020830 0.789 rs17408112 chr9:37114065 A/G cg14294708 chr9:37120828 ZCCHC7 1.14 26.43 0.82 1.25e-84 Schizophrenia; LIHC cis rs1707322 0.686 rs61784833 chr1:46233772 T/C cg06784218 chr1:46089804 CCDC17 0.42 7.74 0.39 1.13e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs35123781 0.696 rs4912755 chr5:139070651 A/G cg10513866 chr5:139070639 NA 0.45 5.86 0.3 1.11e-8 Schizophrenia; LIHC cis rs9457247 1.000 rs2013815 chr6:167373812 T/A cg23791538 chr6:167370224 RNASET2 0.69 11.77 0.54 4.42e-27 Crohn's disease; LIHC cis rs7412746 0.658 rs12067685 chr1:150952917 T/C cg15448220 chr1:150897856 SETDB1 0.43 6.73 0.34 7.07e-11 Melanoma; LIHC cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg11890956 chr21:40555474 PSMG1 1.01 13.49 0.59 1.47e-33 Cognitive function; LIHC cis rs2228479 0.681 rs10153055 chr16:89965842 C/T cg04013166 chr16:89971882 TCF25 0.64 8.32 0.41 2.11e-15 Skin colour saturation; LIHC cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg23982607 chr1:1823379 GNB1 -0.7 -13.37 -0.59 4.49e-33 Body mass index; LIHC cis rs597539 0.652 rs660614 chr11:68659488 G/A cg06028808 chr11:68637592 NA 0.44 5.78 0.3 1.7e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2257205 0.667 rs9899893 chr17:56754597 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -6.47 -0.33 3.49e-10 Pancreatic cancer; LIHC cis rs11761441 0.669 rs13241486 chr7:79536 G/C cg12845006 chr7:82380 NA 0.38 7.26 0.37 2.61e-12 Alzheimer's disease in APOE e4- carriers; LIHC cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg09904177 chr6:26538194 HMGN4 0.56 10.87 0.51 7.82e-24 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg05564831 chr3:52568323 NT5DC2 0.37 5.91 0.3 8.46e-9 Bipolar disorder; LIHC cis rs9910055 0.530 rs11656758 chr17:42301541 A/G cg19774624 chr17:42201019 HDAC5 -0.56 -7.85 -0.39 5.26e-14 Total body bone mineral density; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg14257396 chr1:107603778 NA -0.35 -5.92 -0.3 8.04e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg10130564 chr11:117069849 TAGLN 0.37 6.3 0.32 9.03e-10 Blood protein levels; LIHC cis rs4319547 0.661 rs10846830 chr12:122897220 C/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.34 -0.37 1.54e-12 Body mass index; LIHC cis rs1003719 0.788 rs4816560 chr21:38487561 G/T cg10648535 chr21:38446584 PIGP;TTC3 0.74 11.34 0.52 1.56e-25 Eye color traits; LIHC cis rs9640161 0.789 rs60283368 chr7:150023258 G/A cg17279839 chr7:150038598 RARRES2 0.5 10.59 0.5 7.42e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Bipolar disorder; LIHC cis rs2204008 0.583 rs12820907 chr12:37990931 T/C cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC trans rs12428820 0.615 rs9537077 chr13:55913054 A/C cg18058532 chr11:31832710 PAX6 -0.53 -6.11 -0.31 2.64e-9 Pediatric bone mineral content (hip); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15623503 chr8:12990913 DLC1 -0.59 -6.6 -0.34 1.57e-10 Systolic blood pressure; LIHC cis rs72653721 0.793 rs57864468 chr6:10966671 G/C cg13562911 chr6:11044106 ELOVL2 0.48 6.83 0.35 3.96e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs9427116 0.677 rs9426831 chr1:154609657 A/T cg17218026 chr1:154582156 ADAR -0.34 -6.5 -0.33 2.83e-10 Blood protein levels; LIHC cis rs35110281 0.667 rs4819287 chr21:45120147 A/G cg04455712 chr21:45112962 RRP1B 0.47 8.08 0.4 1.09e-14 Mean corpuscular volume; LIHC cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.91 -0.39 3.5e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs875971 0.862 rs6460282 chr7:65691246 T/C cg18876405 chr7:65276391 NA -0.37 -6.64 -0.34 1.2e-10 Aortic root size; LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg11062466 chr8:58055876 NA 0.5 7.42 0.37 9.65e-13 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.866 rs9991221 chr4:120292107 G/C cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs7917772 0.636 rs2253709 chr10:104542745 T/A cg22532475 chr10:104410764 TRIM8 -0.36 -6.25 -0.32 1.22e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2404602 0.611 rs2404734 chr15:76936165 T/C cg23625390 chr15:77176239 SCAPER -0.53 -8.71 -0.43 1.28e-16 Blood metabolite levels; LIHC cis rs473651 0.935 rs515412 chr2:239345394 A/T cg18131467 chr2:239335373 ASB1 1.03 18.9 0.71 4.73e-55 Multiple system atrophy; LIHC cis rs317689 0.819 rs317677 chr12:69691806 G/A cg14784868 chr12:69753453 YEATS4 0.59 8.59 0.42 3.03e-16 Response to diuretic therapy; LIHC cis rs7131987 0.801 rs6487804 chr12:29454934 G/A cg00204748 chr12:29376779 FAR2 0.34 6.47 0.33 3.46e-10 QT interval; LIHC cis rs929354 0.772 rs6459738 chr7:156998532 T/G cg16102536 chr7:156981717 UBE3C 0.35 5.85 0.3 1.17e-8 Body mass index; LIHC cis rs509477 0.718 rs273348 chr18:32601632 A/C cg23791764 chr18:32556832 MAPRE2 0.48 6.64 0.34 1.22e-10 Cerebrospinal fluid AB1-42 levels; LIHC cis rs1005277 0.579 rs1780115 chr10:38524773 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1348850 0.632 rs10167783 chr2:178519041 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.85 0.39 5.31e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7119 0.717 rs16968835 chr15:77734261 G/A cg17802220 chr15:77601643 NA -0.36 -6.55 -0.33 2.06e-10 Type 2 diabetes; LIHC cis rs8062405 0.691 rs743590 chr16:28608230 G/A cg07382826 chr16:28625726 SULT1A1 0.51 7.92 0.39 3.32e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7726839 0.526 rs55647623 chr5:567747 T/C cg09021430 chr5:549028 NA -0.4 -8.45 -0.42 8.25e-16 Obesity-related traits; LIHC cis rs1023500 0.573 rs1807494 chr22:42474138 C/G cg15557168 chr22:42548783 NA 0.42 6.7 0.34 8.59e-11 Schizophrenia; LIHC cis rs9649465 0.935 rs1605285 chr7:123374412 A/G cg03229431 chr7:123269106 ASB15 -0.37 -7.92 -0.39 3.46e-14 Migraine; LIHC cis rs3764618 0.892 rs3764616 chr19:49497022 A/C cg14640682 chr19:49496473 GYS1;RUVBL2 -0.71 -5.81 -0.3 1.41e-8 Follicule stimulating hormone; LIHC cis rs2153535 0.580 rs1119691 chr6:8460452 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs919433 0.889 rs12472355 chr2:198205840 C/A cg10820045 chr2:198174542 NA -0.56 -9.18 -0.44 4.13e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9858542 1.000 rs13085791 chr3:49721798 C/A cg02487422 chr3:49467188 NICN1 -0.44 -5.79 -0.3 1.63e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs17854409 0.803 rs1048109 chr20:61472120 G/A cg05147244 chr20:61493195 TCFL5 1.23 10.89 0.51 6.79e-24 Obesity-related traits; LIHC cis rs875971 0.862 rs35034167 chr7:65580166 C/G cg18876405 chr7:65276391 NA -0.39 -6.85 -0.35 3.53e-11 Aortic root size; LIHC cis rs7246657 0.943 rs713256 chr19:37865365 C/T cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs5758511 0.514 rs5758580 chr22:42493875 T/C cg00645731 chr22:42541494 CYP2D7P1 0.48 7.75 0.39 1.08e-13 Birth weight; LIHC cis rs6964587 1.000 rs10235941 chr7:91587050 T/G cg17063962 chr7:91808500 NA 1.01 19.29 0.72 1.3e-56 Breast cancer; LIHC cis rs477692 1.000 rs553371 chr10:131413676 T/C cg05714579 chr10:131428358 MGMT 0.45 7.34 0.37 1.56e-12 Response to temozolomide; LIHC cis rs3736485 0.934 rs1077361 chr15:51880919 T/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs514406 0.760 rs475969 chr1:53292607 T/A cg16325326 chr1:53192061 ZYG11B 0.36 5.82 0.3 1.36e-8 Monocyte count; LIHC cis rs9399135 0.967 rs12661423 chr6:135349570 C/T cg24558204 chr6:135376177 HBS1L 0.43 6.75 0.34 6.51e-11 Red blood cell count; LIHC cis rs7582720 1.000 rs72936872 chr2:203790889 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs8062405 0.723 rs62031562 chr16:28609329 A/T cg07382826 chr16:28625726 SULT1A1 0.52 7.89 0.39 4.02e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9522267 0.535 rs6492373 chr13:112238627 T/C cg10483660 chr13:112241077 NA 0.22 5.84 0.3 1.21e-8 Hepatitis; LIHC cis rs7937890 0.559 rs2597219 chr11:14530866 C/G cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs9952991 0.941 rs2542151 chr18:12779947 G/T cg23598886 chr18:12777645 NA 0.44 6.05 0.31 3.88e-9 Inflammatory skin disease; LIHC cis rs10431058 1.000 rs10431058 chr11:107481518 A/G cg18204760 chr11:107461044 ELMOD1;LOC643923 -0.42 -6.79 -0.34 4.96e-11 Common traits (Other); LIHC cis rs10078 0.571 rs2671890 chr5:456457 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.76 10.04 0.48 6.09e-21 Fat distribution (HIV); LIHC cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg06634786 chr22:41940651 POLR3H 0.81 9.13 0.44 6.14e-18 Vitiligo; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg23894205 chr12:14967370 C12orf69;C12orf60 -0.29 -7.13 -0.36 6.14e-12 Calcium levels; LIHC cis rs4474465 0.688 rs7940507 chr11:78284453 T/C cg02023728 chr11:77925099 USP35 -0.33 -5.92 -0.3 7.73e-9 Alzheimer's disease (survival time); LIHC cis rs780096 0.526 rs7602534 chr2:27592423 C/T cg22903471 chr2:27725779 GCKR -0.52 -9.09 -0.44 8.14e-18 Total body bone mineral density; LIHC cis rs9640161 0.789 rs4554381 chr7:150025567 G/A cg17279839 chr7:150038598 RARRES2 0.5 10.44 0.49 2.49e-22 Blood protein levels;Circulating chemerin levels; LIHC cis rs8103278 1.000 rs8108590 chr19:46301620 A/G cg11657440 chr19:46296263 DMWD -0.53 -8.35 -0.41 1.76e-15 Coronary artery disease; LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg11062466 chr8:58055876 NA 0.47 6.43 0.33 4.25e-10 Developmental language disorder (linguistic errors); LIHC cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.47 -7.74 -0.39 1.15e-13 Bipolar disorder; LIHC cis rs10876993 0.784 rs1871417 chr12:58018979 C/T cg15848620 chr12:58087721 OS9 0.5 6.53 0.33 2.37e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs10193935 0.792 rs222472 chr2:42662911 C/T cg27598129 chr2:42591480 NA -0.69 -10.39 -0.49 3.73e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs7937890 0.532 rs2575833 chr11:14492505 A/C cg02886208 chr11:14281011 SPON1 -0.46 -6.47 -0.33 3.47e-10 Mitochondrial DNA levels; LIHC cis rs4631830 0.863 rs2249986 chr10:51521684 T/G cg20129853 chr10:51489980 NA -0.42 -9.19 -0.45 3.82e-18 Prostate-specific antigen levels; LIHC cis rs138880 0.542 rs9616215 chr22:50318834 C/T cg09182678 chr22:50328711 NA -0.7 -8.0 -0.4 1.94e-14 Schizophrenia; LIHC cis rs4746818 1.000 rs7916991 chr10:70895373 C/A cg11621586 chr10:70884670 VPS26A 0.85 12.36 0.56 2.85e-29 Left atrial antero-posterior diameter; LIHC cis rs2439831 0.681 rs498837 chr15:43608024 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.9 16.94 0.68 3.66e-47 Lung cancer in ever smokers; LIHC cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg20818283 chr2:191399100 TMEM194B 0.45 6.17 0.32 1.96e-9 Pulse pressure; LIHC cis rs2257205 0.667 rs79155614 chr17:56722496 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs6831352 0.918 rs2851249 chr4:100044822 T/C cg12011299 chr4:100065546 ADH4 0.62 10.4 0.49 3.54e-22 Alcohol dependence; LIHC cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.44 0.53 7.17e-26 Alzheimer's disease; LIHC cis rs9297145 0.565 rs6952161 chr7:98733337 A/G cg05967295 chr7:98741636 SMURF1 0.35 5.83 0.3 1.27e-8 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs6446731 0.734 rs10937921 chr4:3276491 C/T cg06533319 chr4:3265114 C4orf44 -0.3 -5.73 -0.3 2.21e-8 Mean platelet volume; LIHC cis rs7552404 1.000 rs6593585 chr1:76140273 G/A cg10523679 chr1:76189770 ACADM 0.65 9.23 0.45 2.93e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4919087 1.000 rs61863767 chr10:99084426 C/T cg25902810 chr10:99078978 FRAT1 0.69 10.46 0.49 2.2e-22 Monocyte count; LIHC cis rs9378688 0.654 rs2450299 chr6:2318710 C/T cg12303981 chr6:2244766 GMDS -0.42 -5.9 -0.3 8.89e-9 Caudate nucleus volume; LIHC trans rs16863064 1.000 rs16863064 chr3:187887577 G/C cg02569115 chr17:76922138 TIMP2 -0.36 -6.22 -0.32 1.41e-9 Schizophrenia; LIHC cis rs9916302 0.904 rs9894500 chr17:37515735 G/C cg03013999 chr17:37608204 MED1 -0.34 -5.76 -0.3 1.91e-8 Glomerular filtration rate (creatinine); LIHC cis rs17002069 0.836 rs55916800 chr22:41049315 T/C cg14879645 chr22:41048474 NA 0.4 5.91 0.3 8.13e-9 Schizophrenia; LIHC cis rs2412488 0.893 rs6839922 chr4:54359468 C/G cg22241045 chr4:54363911 LNX1 0.46 7.66 0.38 1.93e-13 DNA methylation (variation); LIHC cis rs7212938 0.570 rs8071050 chr17:38106599 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.39 -5.82 -0.3 1.35e-8 Asthma and hay fever; LIHC cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg24531977 chr5:56204891 C5orf35 0.65 8.9 0.43 3.28e-17 Initial pursuit acceleration; LIHC cis rs9814567 1.000 rs9814567 chr3:134218557 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.19 0.32 1.71e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs507080 0.883 rs692750 chr11:118538308 G/T cg04173919 chr11:118528438 PHLDB1 0.32 6.03 0.31 4.21e-9 Serum metabolite levels; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.85 -0.3 1.14e-8 Total body bone mineral density; LIHC cis rs600806 0.778 rs10776698 chr1:110013630 C/T cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.44 -0.37 8.44e-13 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13036575 chr4:39184472 WDR19 -0.41 -6.03 -0.31 4.14e-9 Cognitive function; LIHC cis rs77861329 1.000 rs9816434 chr3:52197513 C/T cg08692210 chr3:52188851 WDR51A 0.82 7.67 0.38 1.85e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg06481639 chr22:41940642 POLR3H -0.74 -7.36 -0.37 1.41e-12 Vitiligo; LIHC trans rs3112255 0.935 rs1467130 chr2:101306319 T/C cg06958034 chr1:23346203 KDM1A -0.46 -6.06 -0.31 3.55e-9 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.95e-9 Menopause (age at onset); LIHC cis rs1008375 0.966 rs4698636 chr4:17632834 T/C cg16339924 chr4:17578868 LAP3 0.45 6.27 0.32 1.09e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2404602 0.647 rs62026889 chr15:76917885 C/T cg03037974 chr15:76606532 NA -0.61 -10.22 -0.48 1.38e-21 Blood metabolite levels; LIHC cis rs2153535 0.580 rs1119689 chr6:8460754 C/G cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.28e-27 Motion sickness; LIHC cis rs7208859 0.673 rs11654331 chr17:29165017 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12594515 1.000 rs8029209 chr15:45993489 A/G cg01629716 chr15:45996671 NA 0.51 9.16 0.44 4.72e-18 Waist circumference;Weight; LIHC cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.8 -0.57 6.21e-31 Alzheimer's disease; LIHC cis rs6840360 1.000 rs17360475 chr4:152671640 C/G cg22705602 chr4:152727874 NA 0.34 7.24 0.36 3.05e-12 Intelligence (multi-trait analysis); LIHC cis rs9399135 0.967 rs7750300 chr6:135350950 C/G cg22676075 chr6:135203613 NA 0.42 6.79 0.34 5.01e-11 Red blood cell count; LIHC cis rs12824058 0.831 rs4759655 chr12:130815740 A/G cg26677194 chr12:130822605 PIWIL1 -0.52 -7.42 -0.37 9.26e-13 Menopause (age at onset); LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg09455208 chr3:40491958 NA 0.41 8.31 0.41 2.34e-15 Renal cell carcinoma; LIHC cis rs10792665 0.724 rs1904427 chr11:82714248 A/G cg24227371 chr11:82718527 RAB30 -0.38 -9.44 -0.45 6.14e-19 Obesity-related traits; LIHC trans rs11157436 0.918 rs1983520 chr14:22618343 A/C cg13567813 chr19:50879636 NR1H2 0.43 6.28 0.32 1.02e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs10751667 0.666 rs7395402 chr11:950293 A/G cg06064525 chr11:970664 AP2A2 0.57 15.22 0.64 2.55e-40 Alzheimer's disease (late onset); LIHC cis rs9814567 1.000 rs1880377 chr3:134270468 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs208520 0.802 rs851600 chr6:66893754 T/C cg07460842 chr6:66804631 NA -0.76 -8.55 -0.42 4.17e-16 Exhaled nitric oxide output; LIHC cis rs8084351 0.599 rs7506904 chr18:50625779 G/A cg24270629 chr18:50823537 DCC 0.39 5.89 0.3 9.18e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7551222 0.749 rs10900600 chr1:204559707 G/T cg20240347 chr1:204465584 NA -0.31 -6.14 -0.32 2.32e-9 Schizophrenia; LIHC cis rs11588062 0.703 rs11589812 chr1:46858748 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.49 7.72 0.39 1.33e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6942756 1.000 rs67997229 chr7:128957366 G/C cg02491457 chr7:128862824 NA -0.63 -9.0 -0.44 1.58e-17 White matter hyperintensity burden; LIHC cis rs5769765 0.874 rs4624 chr22:50281917 A/G cg02269571 chr22:50332266 NA 0.61 8.64 0.42 2.24e-16 Schizophrenia; LIHC cis rs9457247 0.602 rs6456152 chr6:167472062 A/G cg12798992 chr6:167411361 FGFR1OP 0.47 6.97 0.35 1.63e-11 Crohn's disease; LIHC cis rs10779751 1.000 rs2076655 chr1:11289161 A/G cg08854313 chr1:11322531 MTOR -0.86 -15.43 -0.64 3.83e-41 Body mass index; LIHC cis rs7493 0.755 rs34774523 chr7:94962142 G/A cg17330251 chr7:94953956 PON1 -0.46 -6.0 -0.31 5.07e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs17384381 0.700 rs11161616 chr1:85907625 A/G cg16011679 chr1:85725395 C1orf52 -0.59 -7.05 -0.36 9.82e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg04944784 chr2:26401820 FAM59B 0.71 9.07 0.44 9.29e-18 Gut microbiome composition (summer); LIHC cis rs1862618 0.671 rs2591965 chr5:56236176 T/C cg24531977 chr5:56204891 C5orf35 0.52 7.44 0.37 8.45e-13 Initial pursuit acceleration; LIHC cis rs1538970 0.851 rs2055145 chr1:45926495 C/G cg05343316 chr1:45956843 TESK2 0.6 9.12 0.44 6.65e-18 Platelet count; LIHC cis rs600806 0.778 rs2115787 chr1:110003840 T/G cg11161837 chr1:110010384 SYPL2 0.45 6.06 0.31 3.51e-9 Intelligence (multi-trait analysis); LIHC cis rs748404 0.631 rs4296223 chr15:43645246 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.99 0.48 9e-21 Lung cancer; LIHC cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg08645402 chr16:4508243 NA 0.41 7.6 0.38 2.79e-13 Schizophrenia; LIHC cis rs644799 1.000 rs596277 chr11:95566886 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.71 0.67 3.15e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9914988 0.943 rs66588554 chr17:27141110 A/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs611744 0.967 rs702805 chr8:109235929 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg11965913 chr1:205819406 PM20D1 0.63 9.21 0.45 3.37e-18 Menarche (age at onset); LIHC cis rs1348850 0.526 rs1345138 chr2:178387100 A/T cg27490568 chr2:178487706 NA 1.07 11.81 0.54 3.07e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10792665 0.512 rs7118894 chr11:82606385 G/A cg24227371 chr11:82718527 RAB30 -0.28 -6.57 -0.33 1.86e-10 Obesity-related traits; LIHC cis rs2795502 1.000 rs2142991 chr10:43341105 C/T cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg16405210 chr4:1374714 KIAA1530 -0.4 -5.98 -0.31 5.47e-9 Obesity-related traits; LIHC cis rs4653767 1.000 rs4653767 chr1:226916078 T/C cg05262829 chr1:226921576 ITPKB 0.43 8.18 0.4 5.56e-15 Parkinson's disease; LIHC cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg16822855 chr3:40428330 ENTPD3 0.34 6.26 0.32 1.15e-9 Renal cell carcinoma; LIHC cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg18867708 chr6:26865862 GUSBL1 0.5 7.39 0.37 1.15e-12 Schizophrenia; LIHC cis rs1865760 0.964 rs9295677 chr6:25933712 T/C cg15691649 chr6:25882328 NA -0.38 -5.86 -0.3 1.09e-8 Height; LIHC cis rs12711979 0.509 rs10181286 chr2:3824567 G/A cg17052675 chr2:3827356 NA -0.7 -15.47 -0.64 2.8e-41 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs6840360 1.000 rs3749562 chr4:152596540 T/C cg22705602 chr4:152727874 NA -0.29 -6.2 -0.32 1.61e-9 Intelligence (multi-trait analysis); LIHC cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg03396347 chr1:1875803 NA -0.48 -8.95 -0.44 2.36e-17 Body mass index; LIHC cis rs11098499 0.909 rs35111518 chr4:120440682 A/G cg09307838 chr4:120376055 NA 0.77 11.85 0.54 2.25e-27 Corneal astigmatism; LIHC cis rs10864907 0.553 rs7580877 chr2:113718310 C/A cg12858261 chr2:113808755 IL1F8 0.35 6.0 0.31 5.13e-9 Pulmonary function; LIHC trans rs10213084 1.000 rs10212913 chr4:147499058 T/C cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs2625529 0.818 rs2246225 chr15:72115230 C/T cg16672083 chr15:72433130 SENP8 0.34 6.33 0.32 7.91e-10 Red blood cell count; LIHC cis rs992157 0.735 rs13393821 chr2:219076742 C/G cg00012203 chr2:219082015 ARPC2 0.92 16.6 0.67 8.07e-46 Colorectal cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13795838 chr10:134539818 INPP5A 0.47 6.72 0.34 7.53e-11 Longevity; LIHC cis rs8017423 0.935 rs7158410 chr14:90704370 T/C cg04374321 chr14:90722782 PSMC1 0.74 14.15 0.61 4.13e-36 Mortality in heart failure; LIHC cis rs2204008 0.557 rs11520191 chr12:38197057 T/A cg13010199 chr12:38710504 ALG10B 0.5 5.88 0.3 9.65e-9 Bladder cancer; LIHC cis rs8180040 0.620 rs11720139 chr3:47036756 C/G cg27129171 chr3:47204927 SETD2 -0.54 -8.87 -0.43 4.23e-17 Colorectal cancer; LIHC cis rs7100689 0.646 rs1953971 chr10:82145647 G/C cg00277334 chr10:82204260 NA -0.58 -7.53 -0.38 4.6e-13 Post bronchodilator FEV1; LIHC cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg04267008 chr7:1944627 MAD1L1 -0.58 -9.0 -0.44 1.6e-17 Bipolar disorder and schizophrenia; LIHC cis rs561341 0.783 rs512698 chr17:30292507 G/T cg00745463 chr17:30367425 LRRC37B -0.77 -5.71 -0.3 2.43e-8 Hip circumference adjusted for BMI; LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.4 0.81 1.03e-80 Prudent dietary pattern; LIHC trans rs7395662 0.500 rs1304199 chr11:48699032 A/G cg03929089 chr4:120376271 NA -0.44 -6.66 -0.34 1.12e-10 HDL cholesterol; LIHC cis rs2576037 0.583 rs9960463 chr18:44522808 T/A cg19077165 chr18:44547161 KATNAL2 -0.47 -6.81 -0.35 4.34e-11 Personality dimensions; LIHC cis rs722599 0.562 rs2193597 chr14:75234329 G/A cg11812906 chr14:75593930 NEK9 0.41 6.34 0.32 7.2e-10 IgG glycosylation; LIHC cis rs9486719 1.000 rs2472890 chr6:96867646 C/T cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC trans rs4263408 0.934 rs9683743 chr4:39703194 A/C cg22463517 chr17:26988906 SDF2;SUPT6H 0.44 6.04 0.31 4e-9 Plasma amyloid beta peptide concentrations (ABx-40); LIHC trans rs704178 0.967 rs829079 chr12:21999108 A/C cg19978540 chr12:3409405 NA 0.34 6.04 0.31 4.09e-9 Hippocampal sclerosis of aging; LIHC cis rs12602172 1 rs12602172 chr17:38163567 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.14 -0.44 5.58e-18 Neutrophil percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 10.53 0.49 1.23e-22 Platelet count; LIHC cis rs2439831 1.000 rs28628574 chr15:43802038 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.58 6.75 0.34 6.29e-11 Lung cancer in ever smokers; LIHC cis rs6733011 0.508 rs13004700 chr2:99527568 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.62 -0.34 1.42e-10 Bipolar disorder; LIHC cis rs7539409 0.651 rs6696140 chr1:84317468 C/T cg10977910 chr1:84465055 TTLL7 -0.73 -7.25 -0.37 2.79e-12 Alzheimer's disease; LIHC cis rs734999 0.967 rs10752745 chr1:2507938 A/G cg18854424 chr1:2615690 NA 0.31 6.51 0.33 2.71e-10 Ulcerative colitis; LIHC cis rs3814244 0.528 rs11177002 chr12:68397157 C/T cg15249341 chr12:68405565 NA -0.33 -6.37 -0.33 6.11e-10 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs4942242 0.663 rs9525817 chr13:44225189 C/T cg19169023 chr15:41853346 TYRO3 0.54 7.47 0.37 6.75e-13 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg07725925 chr16:89976287 TCF25 0.45 6.16 0.32 2e-9 Skin colour saturation; LIHC cis rs4332037 0.722 rs60346318 chr7:1915824 C/G cg23422044 chr7:1970798 MAD1L1 -0.69 -10.6 -0.5 6.81e-23 Bipolar disorder; LIHC cis rs5769707 0.605 rs9616702 chr22:50025938 A/G cg01652190 chr22:50026171 C22orf34 -0.34 -7.48 -0.37 6.49e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2404602 0.647 rs12913024 chr15:77145216 C/T cg03037974 chr15:76606532 NA -0.59 -9.91 -0.47 1.6e-20 Blood metabolite levels; LIHC cis rs4934494 0.768 rs34379399 chr10:91443283 C/T cg19698084 chr10:91461284 KIF20B -0.49 -6.49 -0.33 2.93e-10 Red blood cell count; LIHC cis rs8062405 0.755 rs62034358 chr16:28587597 G/T cg00204512 chr16:28754710 NA 0.4 6.95 0.35 1.83e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9858542 0.953 rs6766581 chr3:49539401 T/C cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs3768617 0.510 rs2296288 chr1:183072590 T/C ch.1.3577855R chr1:183094577 LAMC1 0.63 11.06 0.51 1.62e-24 Fuchs's corneal dystrophy; LIHC cis rs4934494 0.727 rs3758388 chr10:91488979 A/T cg19698084 chr10:91461284 KIF20B -0.48 -6.4 -0.33 5.06e-10 Red blood cell count; LIHC cis rs7520050 0.966 rs785481 chr1:46554518 G/A cg03146154 chr1:46216737 IPP -0.37 -6.18 -0.32 1.8e-9 Red blood cell count;Reticulocyte count; LIHC trans rs875971 0.545 rs2707851 chr7:66089165 C/T cg26939375 chr7:64535504 NA -0.38 -6.08 -0.31 3.14e-9 Aortic root size; LIHC cis rs2963155 0.518 rs72801054 chr5:142687742 T/C cg17617527 chr5:142782415 NR3C1 0.86 7.71 0.38 1.35e-13 Breast cancer; LIHC cis rs9325144 0.647 rs35254764 chr12:39102928 T/C cg26384229 chr12:38710491 ALG10B -0.41 -5.89 -0.3 9.16e-9 Morning vs. evening chronotype; LIHC cis rs10197940 0.662 rs13555 chr2:152333304 C/A cg19508488 chr2:152266495 RIF1 0.55 7.76 0.39 9.78e-14 Lung cancer; LIHC cis rs10540 0.730 rs12789735 chr11:518509 G/A cg03576123 chr11:487126 PTDSS2 -1.03 -7.25 -0.36 2.89e-12 Body mass index; LIHC cis rs2839186 0.559 rs2277826 chr21:47639492 C/G cg00612595 chr21:47717864 NA 0.36 5.96 0.31 6.27e-9 Testicular germ cell tumor; LIHC cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg00166722 chr3:10149974 C3orf24 0.51 5.87 0.3 1.02e-8 Alzheimer's disease; LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg13409248 chr3:40428643 ENTPD3 0.49 8.21 0.41 4.7e-15 Renal cell carcinoma; LIHC cis rs826838 0.935 rs11169511 chr12:39175802 T/C cg13010199 chr12:38710504 ALG10B 0.51 6.22 0.32 1.42e-9 Heart rate; LIHC cis rs7772486 0.754 rs1415746 chr6:146077107 A/G cg13319975 chr6:146136371 FBXO30 0.36 5.9 0.3 8.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg00149659 chr3:10157352 C3orf10 0.65 6.4 0.33 5.15e-10 Alzheimer's disease; LIHC cis rs10106298 1.000 rs17773903 chr8:103685172 A/G cg10187029 chr8:103597600 NA 0.52 6.96 0.35 1.75e-11 Schizophrenia; LIHC cis rs15676 0.783 rs2280845 chr9:131583170 T/C cg00228799 chr9:131580591 ENDOG 0.49 7.13 0.36 6.06e-12 Blood metabolite levels; LIHC cis rs10504229 1.000 rs72652905 chr8:58188355 A/G cg20607798 chr8:58055168 NA 0.46 5.85 0.3 1.14e-8 Developmental language disorder (linguistic errors); LIHC trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg22968622 chr17:43663579 NA 1.03 11.32 0.52 1.87e-25 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs60871478 1.000 rs34086011 chr7:805430 C/T cg27478167 chr7:817139 HEATR2 -0.41 -5.83 -0.3 1.32e-8 Cerebrospinal P-tau181p levels; LIHC cis rs11122272 0.735 rs2739513 chr1:231515201 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.41 0.45 7.38e-19 Hemoglobin concentration; LIHC cis rs4665809 0.938 rs35844686 chr2:26304949 A/G cg27170947 chr2:26402098 FAM59B 0.56 6.02 0.31 4.47e-9 Gut microbiome composition (summer); LIHC cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg00750074 chr16:89608354 SPG7 -0.53 -8.57 -0.42 3.67e-16 Multiple myeloma (IgH translocation); LIHC cis rs2439831 0.850 rs67541383 chr15:44172548 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.62 7.47 0.37 6.93e-13 Lung cancer in ever smokers; LIHC cis rs10876993 0.672 rs2640611 chr12:58037757 T/A cg18357645 chr12:58087776 OS9 0.5 8.11 0.4 9.45e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs7312933 0.966 rs6582375 chr12:42423185 A/T cg01256987 chr12:42539512 GXYLT1 -0.4 -6.67 -0.34 1.02e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs16866061 1.000 rs16866061 chr2:225439844 A/G cg12698349 chr2:225449008 CUL3 0.77 13.39 0.59 3.53e-33 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs1799949 0.860 rs8176279 chr17:41210396 A/C cg25072359 chr17:41440525 NA 0.42 6.68 0.34 9.96e-11 Menopause (age at onset); LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.51 0.62 1.6e-37 Prudent dietary pattern; LIHC cis rs9942416 0.630 rs253388 chr5:74975912 A/G cg19683494 chr5:74908142 NA -0.67 -9.29 -0.45 1.85e-18 Age-related disease endophenotypes; LIHC cis rs13223928 0.565 rs10240820 chr7:3154415 T/C cg19214707 chr7:3157722 NA -0.43 -8.26 -0.41 3.28e-15 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs6748734 0.894 rs4675869 chr2:241827696 A/G cg09990169 chr2:241835740 C2orf54 -0.67 -9.56 -0.46 2.34e-19 Urinary metabolites; LIHC cis rs921968 0.643 rs590771 chr2:219369851 C/T cg17980119 chr2:219472607 PLCD4 0.35 6.05 0.31 3.84e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs10791097 0.967 rs1944142 chr11:130717440 C/T cg12179176 chr11:130786555 SNX19 0.6 9.15 0.44 5.11e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2070488 0.813 rs3749387 chr3:38496193 G/C cg24069376 chr3:38537580 EXOG 0.42 7.64 0.38 2.26e-13 Electrocardiographic conduction measures; LIHC cis rs7131987 0.845 rs7299861 chr12:29409667 G/A cg05697976 chr12:29376483 FAR2 0.33 6.76 0.34 6.05e-11 QT interval; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00767560 chr19:19887256 LOC284440 0.51 7.25 0.36 2.72e-12 Pancreatic cancer; LIHC cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg26939375 chr7:64535504 NA 0.47 7.19 0.36 4.13e-12 Calcium levels; LIHC cis rs62458065 1.000 rs979355 chr7:32463933 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.65 7.41 0.37 1.01e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs7312933 0.528 rs10880238 chr12:42489613 A/G cg17420585 chr12:42539391 GXYLT1 -0.57 -9.85 -0.47 2.64e-20 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs12048904 0.964 rs17123467 chr1:101331760 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 8.03 0.4 1.63e-14 Multiple sclerosis; LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg02782426 chr3:40428986 ENTPD3 0.34 6.39 0.33 5.45e-10 Renal cell carcinoma; LIHC cis rs3820500 0.543 rs9727433 chr1:117967602 T/A cg20383390 chr1:117909022 MAN1A2 0.44 5.72 0.3 2.34e-8 Pneumonia; LIHC cis rs13118159 0.872 rs4974605 chr4:1346389 C/G cg16405210 chr4:1374714 KIAA1530 -0.57 -7.21 -0.36 3.6e-12 Longevity; LIHC cis rs2439831 0.571 rs2470121 chr15:43937618 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.87 0.35 3.04e-11 Lung cancer in ever smokers; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg16900814 chr1:173990879 NA 0.51 6.17 0.32 1.92e-9 Glycated hemoglobin levels; LIHC cis rs6089829 0.926 rs6062395 chr20:61667904 A/G cg08564027 chr20:61660810 NA 0.4 7.59 0.38 3.02e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs9378688 0.929 rs9392373 chr6:2210006 T/A cg12303981 chr6:2244766 GMDS -0.51 -6.53 -0.33 2.45e-10 Caudate nucleus volume; LIHC trans rs1005277 0.522 rs289645 chr10:37943642 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.53 -0.33 2.41e-10 Extrinsic epigenetic age acceleration; LIHC cis rs875971 0.660 rs1860470 chr7:66103694 G/C cg14393609 chr7:65229607 NA -0.37 -5.76 -0.3 1.83e-8 Aortic root size; LIHC cis rs11888559 0.655 rs4675314 chr2:204005532 A/G cg24605529 chr2:203879461 NBEAL1 0.8 6.1 0.31 2.8e-9 Height; LIHC cis rs4663866 0.901 rs3739067 chr2:239184203 G/A cg16914508 chr2:239161102 PER2 0.81 5.74 0.3 2.13e-8 Irritable bowel syndrome; LIHC cis rs6964587 0.773 rs12740 chr7:92029302 A/G cg17063962 chr7:91808500 NA 0.92 16.22 0.66 2.79e-44 Breast cancer; LIHC cis rs3815700 1.000 rs8108840 chr19:33094452 A/C cg02997394 chr19:33096574 ANKRD27 0.72 9.04 0.44 1.2e-17 Eosinophilic esophagitis; LIHC cis rs10791097 0.694 rs1893018 chr11:130756632 T/C cg14779329 chr11:130786720 SNX19 0.42 6.34 0.32 7.1e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7208859 0.623 rs59447372 chr17:29057585 C/T cg13385521 chr17:29058706 SUZ12P 0.84 8.37 0.41 1.49e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12497850 0.931 rs9846123 chr3:49088112 C/T cg06212747 chr3:49208901 KLHDC8B -0.59 -7.81 -0.39 7.18e-14 Parkinson's disease; LIHC cis rs6754311 0.597 rs2082729 chr2:136550109 C/T cg17750252 chr2:136567154 LCT 0.36 6.32 0.32 7.97e-10 Mosquito bite size; LIHC cis rs9814567 1.000 rs13087875 chr3:134261123 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs929354 0.772 rs2366214 chr7:156992461 A/G cg17757837 chr7:157058334 UBE3C 0.74 11.96 0.54 8.97e-28 Body mass index; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg09922871 chr2:71559595 ZNF638 -0.41 -6.45 -0.33 3.84e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16804848 chr11:64052165 GPR137;BAD 0.5 6.85 0.35 3.52e-11 Lung function (FEV1/FVC); LIHC cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg16049864 chr8:95962084 TP53INP1 -0.65 -12.36 -0.56 3e-29 Type 2 diabetes; LIHC trans rs2262909 0.962 rs55735642 chr19:22241176 C/T cg17074339 chr11:11642133 GALNTL4 0.4 6.09 0.31 3.09e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs8067545 0.750 rs4924804 chr17:19991839 C/T cg13482628 chr17:19912719 NA 0.52 8.76 0.43 9.25e-17 Schizophrenia; LIHC cis rs2228479 0.702 rs17233176 chr16:89832751 G/C cg00800038 chr16:89945340 TCF25 -0.61 -8.97 -0.44 1.96e-17 Skin colour saturation; LIHC cis rs9381040 1.000 rs2093395 chr6:41155026 C/G cg04346459 chr6:41068666 NFYA;LOC221442 0.39 6.37 0.33 6.06e-10 Alzheimer's disease (late onset); LIHC cis rs4919087 1.000 rs11189127 chr10:99079023 G/A cg25902810 chr10:99078978 FRAT1 0.7 10.77 0.5 1.68e-23 Monocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05310920 chr2:150186634 LYPD6 0.44 6.24 0.32 1.32e-9 Lung function (FEV1/FVC); LIHC cis rs1577917 1.000 rs12663690 chr6:86640162 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.6 10.68 0.5 3.6e-23 Response to antipsychotic treatment; LIHC cis rs4474465 1.000 rs7925034 chr11:78193242 A/G cg27205649 chr11:78285834 NARS2 -0.38 -5.71 -0.3 2.43e-8 Alzheimer's disease (survival time); LIHC cis rs11105298 0.891 rs10858906 chr12:89934474 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.53 -0.38 4.6e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs17401966 0.838 rs12139981 chr1:10390696 T/C cg19773385 chr1:10388646 KIF1B -0.4 -7.09 -0.36 7.59e-12 Hepatocellular carcinoma; LIHC cis rs6542838 0.611 rs1976766 chr2:99522754 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.2 -0.32 1.58e-9 Fear of minor pain; LIHC cis rs1198430 1.000 rs1198439 chr1:23749593 A/T cg19827787 chr1:23763612 ASAP3 0.34 6.39 0.33 5.38e-10 Total cholesterol levels; LIHC cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg05665937 chr4:1216051 CTBP1 0.39 6.02 0.31 4.55e-9 Obesity-related traits; LIHC cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg18404041 chr3:52824283 ITIH1 -0.55 -9.03 -0.44 1.31e-17 Bipolar disorder; LIHC cis rs9549328 0.921 rs9549623 chr13:113640293 G/A cg08528486 chr13:113648767 MCF2L -0.39 -6.31 -0.32 8.5e-10 Systolic blood pressure; LIHC cis rs6089829 0.962 rs2872543 chr20:61665017 G/A cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.11e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs597539 0.552 rs6591360 chr11:68718669 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.41 0.49 3.05e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7512552 0.803 rs7513205 chr1:150472781 A/G cg15654264 chr1:150340011 RPRD2 0.71 11.53 0.53 3.24e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs875971 0.964 rs778723 chr7:65829497 T/C cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26080798 chr6:20402092 E2F3 0.54 6.88 0.35 2.94e-11 Lung function (FEV1/FVC); LIHC cis rs3749237 0.595 rs17595772 chr3:49409704 G/A cg07636037 chr3:49044803 WDR6 0.5 7.53 0.38 4.44e-13 Resting heart rate; LIHC cis rs941873 0.805 rs876678 chr10:81111036 G/T cg09469691 chr10:81107165 PPIF 0.66 10.13 0.48 2.85e-21 Height; LIHC cis rs4742903 0.846 rs7022158 chr9:106924872 A/G cg14250997 chr9:106856677 SMC2 0.36 6.06 0.31 3.61e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg08677398 chr8:58056175 NA 0.41 6.16 0.32 2.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs9649213 0.574 rs34830366 chr7:97899535 G/T cg08684580 chr7:98029266 BAIAP2L1 -0.39 -5.96 -0.31 6.17e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg24372485 chr19:2078331 MOBKL2A 0.44 6.52 0.33 2.51e-10 Bilirubin levels; LIHC cis rs9818758 0.505 rs67286839 chr3:49265744 C/T cg06212747 chr3:49208901 KLHDC8B -0.66 -5.87 -0.3 1.01e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs921968 0.643 rs524012 chr2:219433273 T/G cg02985541 chr2:219472218 PLCD4 0.44 8.46 0.42 7.9e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg06710121 chr8:12235606 FAM66A -0.37 -5.88 -0.3 9.65e-9 Monocyte count; LIHC cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg05564831 chr3:52568323 NT5DC2 0.35 5.93 0.31 7.53e-9 Electroencephalogram traits; LIHC cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg18402987 chr7:1209562 NA 0.74 5.88 0.3 9.84e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs8117834 0.574 rs6118058 chr20:8086554 T/C cg00593689 chr4:53575888 NA 0.38 6.44 0.33 3.98e-10 Chronic kidney disease; LIHC cis rs2758596 0.850 rs2842879 chr1:156163695 G/T cg24450063 chr1:156163899 SLC25A44 0.96 10.53 0.49 1.19e-22 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs3806843 1.000 rs10223116 chr5:140192643 C/T cg26395211 chr5:140044315 WDR55 -0.42 -6.12 -0.31 2.53e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9916302 0.861 rs752314 chr17:37410700 C/T cg00129232 chr17:37814104 STARD3 -0.39 -6.29 -0.32 9.75e-10 Glomerular filtration rate (creatinine); LIHC cis rs34779708 0.931 rs11010125 chr10:35502953 A/G cg04310649 chr10:35416472 CREM -0.43 -5.81 -0.3 1.42e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg01171360 chr6:293285 DUSP22 -0.46 -6.76 -0.34 5.84e-11 Menopause (age at onset); LIHC cis rs2904967 0.500 rs3896078 chr11:64874262 C/G cg19545356 chr11:64851426 ZFPL1;CDCA5 -1.01 -6.5 -0.33 2.83e-10 Mean corpuscular volume; LIHC cis rs16958440 0.867 rs62095427 chr18:44594221 G/A cg17192377 chr18:44677553 HDHD2 0.66 6.78 0.34 5.38e-11 Sitting height ratio; LIHC cis rs826838 1.000 rs4575342 chr12:38663831 G/A cg26384229 chr12:38710491 ALG10B 1.08 14.69 0.62 3.18e-38 Heart rate; LIHC trans rs2727020 0.521 rs7126835 chr11:49594658 T/C cg15704280 chr7:45808275 SEPT13 -0.79 -11.89 -0.54 1.62e-27 Coronary artery disease; LIHC cis rs1878931 0.582 rs27232 chr16:3436782 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.44 -0.42 8.96e-16 Body mass index (adult); LIHC trans rs916888 0.821 rs199506 chr17:44859031 A/G cg07870213 chr5:140052090 DND1 -0.99 -10.2 -0.48 1.71e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.29 -0.32 9.81e-10 Total body bone mineral density; LIHC cis rs2839186 0.706 rs2839188 chr21:47692798 C/T cg09417038 chr21:47716443 C21orf57 -0.52 -7.38 -0.37 1.19e-12 Testicular germ cell tumor; LIHC cis rs12893668 0.645 rs12889403 chr14:104034746 C/T cg19000871 chr14:103996768 TRMT61A -0.43 -7.01 -0.35 1.28e-11 Reticulocyte count; LIHC cis rs7582720 1.000 rs114520702 chr2:203697092 C/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9296092 0.538 rs78061112 chr6:33526587 T/G cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg18357526 chr6:26021779 HIST1H4A 0.63 8.91 0.43 3.08e-17 Blood metabolite levels; LIHC cis rs2204008 0.805 rs7296063 chr12:37964775 T/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs933688 1.000 rs4382199 chr5:90744228 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.29 0.66 1.49e-44 Smoking behavior; LIHC cis rs6723226 0.732 rs390480 chr2:32510072 A/C cg02381751 chr2:32503542 YIPF4 -0.76 -11.48 -0.53 5.19e-26 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.663 rs2237277 chr6:167442107 G/A cg12798992 chr6:167411361 FGFR1OP 0.53 8.71 0.43 1.29e-16 Crohn's disease; LIHC cis rs9768139 1.000 rs9768139 chr7:158120731 G/A cg25566285 chr7:158114605 PTPRN2 -0.26 -7.6 -0.38 2.93e-13 Calcium levels; LIHC cis rs35160687 0.509 rs13024436 chr2:86534521 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 0.38 6.07 0.31 3.31e-9 Night sleep phenotypes; LIHC cis rs875971 0.862 rs778724 chr7:65829291 T/C cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs17125944 0.505 rs10483618 chr14:53203590 T/C cg00686598 chr14:53173677 PSMC6 1.21 15.32 0.64 1.04e-40 Alzheimer's disease (late onset); LIHC cis rs3770081 1.000 rs6705122 chr2:86176258 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.39 5.83 0.3 1.27e-8 Facial emotion recognition (sad faces); LIHC cis rs4631830 0.695 rs11004584 chr10:51500088 G/T cg16070123 chr10:51489643 NA -0.38 -6.08 -0.31 3.26e-9 Prostate-specific antigen levels; LIHC cis rs3806843 0.735 rs801185 chr5:140068869 A/G cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.12 0.52 9.62e-25 Platelet count; LIHC cis rs2153535 0.542 rs1120393 chr6:8486890 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs10193935 0.892 rs12612372 chr2:42414035 A/G cg27598129 chr2:42591480 NA -0.73 -11.01 -0.51 2.42e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs9611519 0.929 rs9611466 chr22:41426299 A/T cg03806693 chr22:41940476 POLR3H -0.69 -7.66 -0.38 1.92e-13 Neuroticism; LIHC cis rs4780355 0.619 rs918737 chr16:11439639 T/C cg00044050 chr16:11439710 C16orf75 -0.45 -6.18 -0.32 1.86e-9 Crohn's disease and psoriasis; LIHC cis rs752010 0.746 rs10749837 chr1:42089471 T/C cg06885757 chr1:42089581 HIVEP3 0.32 6.7 0.34 8.61e-11 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs778371 0.522 rs6704768 chr2:233592501 C/T cg25237894 chr2:233734115 C2orf82 0.37 6.99 0.35 1.43e-11 Schizophrenia; LIHC cis rs7703051 0.707 rs7730344 chr5:74587940 C/A cg00601450 chr5:74908170 NA 0.39 5.94 0.31 7.04e-9 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs2806561 0.704 rs664301 chr1:23522522 C/T cg19743168 chr1:23544995 NA 0.38 6.27 0.32 1.07e-9 Height; LIHC cis rs611744 0.934 rs2848619 chr8:109198185 T/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.8e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs151997 0.925 rs27270 chr5:50183712 A/G cg06027927 chr5:50259733 NA -0.56 -7.7 -0.38 1.45e-13 Callous-unemotional behaviour; LIHC cis rs747782 0.639 rs4752872 chr11:47853795 T/C cg20307385 chr11:47447363 PSMC3 -0.54 -5.89 -0.3 9.2e-9 Intraocular pressure; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg26338869 chr17:61819248 STRADA 0.61 8.65 0.42 2.06e-16 Prudent dietary pattern; LIHC cis rs9640161 0.789 rs10952250 chr7:150025966 T/C cg21361702 chr7:150065534 REPIN1 0.45 6.17 0.32 1.94e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs17685 0.712 rs7778735 chr7:75770237 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9309711 0.666 rs4321399 chr2:3481659 G/A cg10845886 chr2:3471009 TTC15 -0.46 -8.78 -0.43 7.98e-17 Neurofibrillary tangles; LIHC cis rs12701220 0.901 rs12701708 chr7:1090333 C/T cg00990874 chr7:1149470 C7orf50 -0.64 -9.08 -0.44 9e-18 Bronchopulmonary dysplasia; LIHC cis rs9733 0.596 rs6669369 chr1:150695892 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs7216064 1.000 rs6504542 chr17:65836642 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.74 -0.47 6.22e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs1552244 0.572 rs59074548 chr3:10164347 G/C cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC trans rs1728785 1.000 rs1170443 chr16:68573295 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.82e-9 Ulcerative colitis; LIHC cis rs6840360 0.593 rs10022023 chr4:152560731 A/G cg22705602 chr4:152727874 NA -0.31 -6.14 -0.32 2.29e-9 Intelligence (multi-trait analysis); LIHC cis rs796364 0.865 rs769948 chr2:200728475 C/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.09 0.44 8.32e-18 Schizophrenia; LIHC cis rs8072100 0.840 rs12453233 chr17:45454570 C/T cg25173405 chr17:45401733 C17orf57 -0.41 -5.79 -0.3 1.55e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs35306767 0.761 rs11253559 chr10:1044809 T/C cg26597838 chr10:835615 NA 0.88 8.33 0.41 1.97e-15 Eosinophil percentage of granulocytes; LIHC cis rs7927592 0.956 rs2155730 chr11:68329474 T/C cg16797656 chr11:68205561 LRP5 0.5 7.83 0.39 6.23e-14 Total body bone mineral density; LIHC cis rs7961581 0.748 rs1588493 chr12:71598228 A/G cg05756094 chr12:71608604 NA 0.4 6.49 0.33 3e-10 Type 2 diabetes; LIHC cis rs9733 0.650 rs6698495 chr1:150564476 T/C cg13175981 chr1:150552382 MCL1 0.63 9.86 0.47 2.47e-20 Tonsillectomy; LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg03264133 chr6:25882463 NA -0.54 -6.87 -0.35 2.95e-11 Intelligence (multi-trait analysis); LIHC cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg18357526 chr6:26021779 HIST1H4A 0.75 9.43 0.45 6.22e-19 Urate levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg04250904 chr19:12623422 ZNF709 0.4 6.42 0.33 4.46e-10 Bilirubin levels; LIHC cis rs12744310 1.000 rs12037560 chr1:41763891 C/A cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs34779708 0.931 rs35886556 chr10:35334985 C/T cg03585969 chr10:35415529 CREM 0.84 12.76 0.57 9.4e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12464559 0.649 rs10171724 chr2:152672482 T/A cg01189475 chr2:152685088 ARL5A 0.63 7.38 0.37 1.2e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs8027181 0.839 rs2304597 chr15:73052431 A/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 8.06 0.4 1.33e-14 Triglyceride levels; LIHC cis rs600806 0.778 rs10494040 chr1:110015732 C/T cg23091122 chr1:110024289 SYPL2 -0.44 -6.09 -0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs1865721 0.804 rs72977818 chr18:73146852 T/C cg26385618 chr18:73139727 C18orf62 -0.3 -7.86 -0.39 4.96e-14 Intelligence; LIHC cis rs1538970 0.781 rs11211139 chr1:46015751 G/T cg06784218 chr1:46089804 CCDC17 0.37 5.82 0.3 1.39e-8 Platelet count; LIHC cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg05665937 chr4:1216051 CTBP1 0.45 6.05 0.31 3.86e-9 Obesity-related traits; LIHC cis rs7937682 0.883 rs631490 chr11:111452040 G/C cg09085632 chr11:111637200 PPP2R1B -0.91 -11.12 -0.52 9.64e-25 Primary sclerosing cholangitis; LIHC trans rs983392 0.709 rs7928895 chr11:59975165 G/A cg17275991 chr19:58003312 ZNF419 0.44 6.14 0.32 2.24e-9 Alzheimer's disease (late onset); LIHC cis rs238295 0.805 rs6053500 chr20:5542683 A/G cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -7.0 -0.35 1.4e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg21724239 chr8:58056113 NA 0.48 6.38 0.33 5.84e-10 Developmental language disorder (linguistic errors); LIHC cis rs6426558 0.537 rs10799381 chr1:227239746 G/T cg10327440 chr1:227177885 CDC42BPA 0.44 6.67 0.34 1.04e-10 Neutrophil percentage of white cells; LIHC cis rs11671005 0.656 rs55928441 chr19:59009674 T/C cg25952890 chr19:58913133 NA 0.67 6.4 0.33 4.99e-10 Mean platelet volume; LIHC cis rs1005277 0.602 rs2504142 chr10:38383793 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs6762 0.719 rs4895 chr11:840477 A/G cg07691484 chr11:842764 TSPAN4;POLR2L -0.75 -9.51 -0.46 3.39e-19 Mean platelet volume; LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg10755058 chr3:40428713 ENTPD3 0.38 6.53 0.33 2.38e-10 Renal cell carcinoma; LIHC cis rs9611565 0.512 rs2899349 chr22:42164660 T/C cg06634786 chr22:41940651 POLR3H 0.73 7.39 0.37 1.15e-12 Vitiligo; LIHC cis rs918629 0.530 rs56156268 chr5:95240659 G/A cg10483112 chr5:95245456 ELL2 -0.38 -6.91 -0.35 2.41e-11 IgG glycosylation; LIHC cis rs507080 0.807 rs7926944 chr11:118559828 T/C cg04173919 chr11:118528438 PHLDB1 0.35 6.58 0.34 1.8e-10 Serum metabolite levels; LIHC cis rs1707322 0.963 rs1768815 chr1:46528603 G/A cg03146154 chr1:46216737 IPP -0.45 -7.08 -0.36 8.2e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2576037 0.583 rs1465722 chr18:44564499 C/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.41 5.84 0.3 1.19e-8 Personality dimensions; LIHC trans rs11039798 0.588 rs10838923 chr11:48534864 C/G cg15704280 chr7:45808275 SEPT13 0.58 6.48 0.33 3.23e-10 Axial length; LIHC cis rs4450131 0.500 rs2362515 chr10:126336158 C/T cg20435097 chr10:126320824 FAM53B 0.69 12.37 0.56 2.56e-29 White blood cell count (basophil); LIHC cis rs1008375 1.000 rs10805357 chr4:17652352 G/A cg04450456 chr4:17643702 FAM184B 0.34 5.74 0.3 2.05e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2997447 0.706 rs2783713 chr1:26429351 C/A cg19633962 chr1:26362018 EXTL1 -0.56 -6.24 -0.32 1.29e-9 QRS complex (12-leadsum); LIHC cis rs1008375 1.000 rs4698198 chr4:17656536 G/A cg16339924 chr4:17578868 LAP3 0.45 6.33 0.32 7.87e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1707322 1.000 rs7547189 chr1:46319514 C/A cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg22105103 chr4:187893119 NA 0.34 8.19 0.4 5.21e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg20295408 chr7:1910781 MAD1L1 -0.48 -6.95 -0.35 1.82e-11 Bipolar disorder and schizophrenia; LIHC cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg08469215 chr1:156261351 TMEM79 -0.38 -6.25 -0.32 1.21e-9 Tonsillectomy; LIHC cis rs57244997 0.685 rs1954916 chr6:162447612 A/G cg17173639 chr6:162384350 PARK2 -0.62 -7.4 -0.37 1.09e-12 Mosquito bite size; LIHC cis rs35306767 0.953 rs1106064 chr10:957211 G/A cg26597838 chr10:835615 NA 0.98 11.98 0.54 7.58e-28 Eosinophil percentage of granulocytes; LIHC cis rs2108622 0.683 rs112571591 chr19:15977445 G/A cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.81e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs34375054 0.738 rs3751181 chr12:125626535 A/G cg25124228 chr12:125621409 AACS -0.42 -7.16 -0.36 5.07e-12 Post bronchodilator FEV1/FVC ratio; LIHC cis rs611744 0.967 rs591792 chr8:109200446 T/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs25645 0.800 rs34003767 chr17:38194296 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.75 14.25 0.61 1.74e-36 Myeloid white cell count; LIHC cis rs274567 0.501 rs272855 chr5:131687175 C/T cg24060327 chr5:131705240 SLC22A5 -0.78 -12.06 -0.55 3.91e-28 Blood metabolite levels; LIHC cis rs11098499 0.754 rs1511025 chr4:120240238 T/C cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs807029 0.533 rs67813203 chr10:102738551 A/G cg25179470 chr10:102756915 LZTS2 0.45 6.38 0.33 5.65e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg19318889 chr4:1322082 MAEA 0.4 6.62 0.34 1.37e-10 Obesity-related traits; LIHC cis rs7412746 0.611 rs10788794 chr1:150728676 T/C cg17724175 chr1:150552817 MCL1 0.47 9.44 0.45 6.14e-19 Melanoma; LIHC cis rs8141529 0.748 rs715531 chr22:29282679 A/G cg02153584 chr22:29168773 CCDC117 0.53 8.17 0.4 5.88e-15 Lymphocyte counts; LIHC cis rs10876993 0.928 rs2169988 chr12:58071165 G/A cg18357645 chr12:58087776 OS9 0.52 8.53 0.42 4.91e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs6089584 0.546 rs6061978 chr20:60615604 C/T cg23262073 chr20:60523788 NA -0.28 -5.87 -0.3 1.04e-8 Body mass index; LIHC cis rs9368481 0.761 rs3931464 chr6:26939856 C/A cg12292205 chr6:26970375 C6orf41 0.47 7.88 0.39 4.39e-14 Autism spectrum disorder or schizophrenia; LIHC cis rs3741404 0.665 rs12418535 chr11:63910980 A/G cg24431193 chr11:63883947 FLRT1;MACROD1 -0.38 -5.9 -0.3 8.94e-9 Platelet count; LIHC trans rs17253792 0.915 rs17832389 chr14:56185836 A/G cg26951091 chr14:76844913 ESRRB 0.58 6.14 0.32 2.34e-9 Putamen volume; LIHC cis rs921968 0.612 rs832810 chr2:219322430 T/C cg18887096 chr2:219472410 PLCD4 0.4 6.96 0.35 1.79e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs748404 0.697 rs530683 chr15:43568999 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.48 -8.09 -0.4 1.04e-14 Lung cancer; LIHC cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg27170947 chr2:26402098 FAM59B 0.67 8.36 0.41 1.59e-15 Mean corpuscular hemoglobin; LIHC cis rs1707322 0.752 rs28812624 chr1:46203736 T/A cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs72627509 0.904 rs7687767 chr4:57824932 C/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.56 8.22 0.41 4.21e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2439831 0.850 rs694985 chr15:43813387 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.71 11.68 0.53 9.78e-27 Lung cancer in ever smokers; LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg08280861 chr8:58055591 NA 0.49 6.13 0.31 2.38e-9 Developmental language disorder (linguistic errors); LIHC cis rs1055129 0.655 rs7223416 chr17:73836162 C/G cg08125733 chr17:73851984 WBP2 0.5 8.24 0.41 3.71e-15 White matter hyperintensity burden; LIHC cis rs4665809 0.887 rs2384324 chr2:26354239 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.77 -9.63 -0.46 1.36e-19 Gut microbiome composition (summer); LIHC cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg17971929 chr21:40555470 PSMG1 0.85 10.33 0.49 5.75e-22 Cognitive function; LIHC cis rs12586317 0.553 rs3809448 chr14:35515096 C/T cg16230307 chr14:35515116 FAM177A1 0.82 13.59 0.59 5.98e-34 Psoriasis; LIHC cis rs5753037 0.504 rs140114 chr22:30133881 C/T cg01021169 chr22:30184971 ASCC2 -0.32 -6.05 -0.31 3.8e-9 Type 1 diabetes; LIHC trans rs800082 0.501 rs9873732 chr3:144191665 C/T cg24215973 chr2:240111563 HDAC4 0.48 6.93 0.35 2.07e-11 Smoking behavior; LIHC cis rs9896933 0.830 rs8074277 chr17:80789628 T/C cg15664640 chr17:80829946 TBCD -0.57 -5.97 -0.31 5.98e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs7940866 0.801 rs2113929 chr11:130835974 G/A cg12179176 chr11:130786555 SNX19 0.62 9.03 0.44 1.28e-17 Schizophrenia; LIHC trans rs1005277 0.579 rs2023351 chr10:38378814 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs921968 0.643 rs864990 chr2:219494037 G/A cg17980119 chr2:219472607 PLCD4 0.34 5.71 0.3 2.4e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2282802 0.635 rs397463 chr5:139584275 C/G cg26211634 chr5:139558579 C5orf32 -0.38 -5.92 -0.31 7.71e-9 Intelligence (multi-trait analysis); LIHC cis rs7103648 0.695 rs12577643 chr11:47467172 A/T cg20307385 chr11:47447363 PSMC3 1.01 15.71 0.65 3.05e-42 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.87 8.18 0.4 5.67e-15 Platelet count; LIHC cis rs9611565 0.568 rs2413656 chr22:42129357 G/T cg03806693 chr22:41940476 POLR3H 0.79 8.97 0.44 1.95e-17 Vitiligo; LIHC cis rs67079557 1 rs67079557 chr15:75930300 ATAATAAG/A cg20655648 chr15:75932815 IMP3 0.46 6.56 0.33 2.01e-10 Breast cancer; LIHC cis rs1577917 0.958 rs13213899 chr6:86473140 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.18 -0.36 4.33e-12 Response to antipsychotic treatment; LIHC cis rs9783347 1.000 rs10741741 chr11:18342081 C/T cg15585147 chr11:18324498 HPS5 -0.37 -6.15 -0.32 2.18e-9 Pancreatic cancer; LIHC cis rs7589728 1.000 rs7589728 chr2:88518440 G/A cg04511125 chr2:88470314 THNSL2 0.76 7.05 0.36 9.82e-12 Plasma clusterin levels; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg14393609 chr7:65229607 NA 0.42 7.11 0.36 6.92e-12 Calcium levels; LIHC cis rs9611519 0.780 rs9611542 chr22:41677317 C/T cg06634786 chr22:41940651 POLR3H -0.57 -6.64 -0.34 1.21e-10 Neuroticism; LIHC cis rs4919087 0.926 rs2861875 chr10:98990139 C/G cg25902810 chr10:99078978 FRAT1 -0.61 -9.05 -0.44 1.11e-17 Monocyte count; LIHC cis rs2760061 0.598 rs849904 chr1:228137145 G/C cg01200585 chr1:228362443 C1orf69 -0.39 -5.78 -0.3 1.7e-8 Diastolic blood pressure; LIHC cis rs7223966 1.000 rs1877316 chr17:61766880 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.58 0.34 1.79e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2731664 0.721 rs2450333 chr5:176899546 G/A cg23176889 chr5:176863531 GRK6 -0.68 -11.94 -0.54 1.08e-27 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02396668 chr19:50528878 VRK3;ZNF473 0.42 6.5 0.33 2.86e-10 Cognitive function; LIHC cis rs12995491 0.569 rs6724281 chr2:88529531 T/G cg24977027 chr2:88469347 THNSL2 -0.46 -6.61 -0.34 1.44e-10 Response to metformin (IC50); LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg19901994 chr8:27288146 PTK2B 0.56 6.07 0.31 3.35e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs611744 0.647 rs9969614 chr8:109260581 A/G cg21045802 chr8:109455806 TTC35 0.57 10.1 0.48 3.58e-21 Dupuytren's disease; LIHC trans rs1814175 0.645 rs1851849 chr11:50012164 G/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs4689592 0.503 rs11945642 chr4:7051065 G/C cg19539972 chr4:7069911 GRPEL1 -0.64 -9.05 -0.44 1.12e-17 Monocyte percentage of white cells; LIHC cis rs644799 0.710 rs56384142 chr11:95502075 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.79 12.04 0.55 4.52e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg07677032 chr17:61819896 STRADA 0.43 6.19 0.32 1.75e-9 Prudent dietary pattern; LIHC cis rs4474465 1.000 rs2373199 chr11:78142982 G/A cg27205649 chr11:78285834 NARS2 -0.39 -5.81 -0.3 1.46e-8 Alzheimer's disease (survival time); LIHC cis rs1983891 0.909 rs4714482 chr6:41528199 G/A cg20194872 chr6:41519635 FOXP4 0.43 6.84 0.35 3.74e-11 Prostate cancer; LIHC cis rs2380220 0.808 rs2716069 chr6:95912976 C/G cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs2370759 1.000 rs76467481 chr10:32610740 T/G cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs611744 0.647 rs628206 chr8:109247873 A/G cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01089589 chr2:10920095 ATP6V1C2 0.46 6.63 0.34 1.29e-10 Longevity; LIHC cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.32 0.45 1.45e-18 Electroencephalogram traits; LIHC cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9457247 0.934 rs2345571 chr6:167403400 T/G cg23791538 chr6:167370224 RNASET2 -0.65 -11.04 -0.51 1.97e-24 Crohn's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04238871 chr10:126431886 FAM53B 0.43 6.44 0.33 4.06e-10 Pancreatic cancer; LIHC cis rs9303280 0.776 rs11078926 chr17:38062976 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.83 0.3 1.3e-8 Self-reported allergy; LIHC cis rs611744 0.816 rs626211 chr8:109189448 A/C cg21045802 chr8:109455806 TTC35 0.59 9.9 0.47 1.7e-20 Dupuytren's disease; LIHC cis rs7511006 1.000 rs7511006 chr22:50676259 T/C cg16473166 chr22:50639996 SELO 0.51 7.26 0.37 2.63e-12 Obesity-related traits; LIHC cis rs35306767 0.807 rs12768348 chr10:899224 T/G cg20503657 chr10:835505 NA 1.33 14.33 0.61 8.06e-37 Eosinophil percentage of granulocytes; LIHC cis rs1552244 0.572 rs3843008 chr3:10173742 C/T cg00149659 chr3:10157352 C3orf10 1.08 9.29 0.45 1.79e-18 Alzheimer's disease; LIHC cis rs12701220 0.696 rs12112029 chr7:1137889 G/A cg26769984 chr7:1090371 C7orf50 0.46 5.77 0.3 1.82e-8 Bronchopulmonary dysplasia; LIHC cis rs7223966 1.000 rs11658329 chr17:61763031 C/G cg23903597 chr17:61704154 MAP3K3 0.44 6.02 0.31 4.42e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs5769707 0.642 rs135880 chr22:50018654 T/A cg07959070 chr22:50026188 C22orf34 -0.34 -8.68 -0.42 1.61e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs72781680 0.660 rs72780104 chr2:23983715 A/G cg08917208 chr2:24149416 ATAD2B 0.83 7.54 0.38 4.22e-13 Lymphocyte counts; LIHC cis rs4808199 0.895 rs6511036 chr19:19582651 A/G cg03709012 chr19:19516395 GATAD2A 1.09 19.43 0.72 3.36e-57 Nonalcoholic fatty liver disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19252891 chr7:75132457 SPDYE5 0.5 6.88 0.35 2.88e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7131987 0.903 rs2194520 chr12:29423712 C/T cg14222432 chr12:29376421 FAR2 0.35 6.64 0.34 1.27e-10 QT interval; LIHC cis rs11971779 0.617 rs66652773 chr7:139109573 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18156793 chr20:32031936 SNTA1 0.44 6.74 0.34 6.72e-11 Pancreatic cancer; LIHC cis rs1865760 0.929 rs2876693 chr6:25954434 C/G cg17691542 chr6:26056736 HIST1H1C 0.39 5.88 0.3 9.8e-9 Height; LIHC cis rs7945718 0.621 rs7943920 chr11:12695614 A/G cg25843174 chr11:12811716 TEAD1 0.33 7.68 0.38 1.7e-13 Educational attainment (years of education); LIHC cis rs763121 0.853 rs5757211 chr22:39051705 C/T cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22379573 chr1:197704774 DENND1B -0.37 -6.11 -0.31 2.64e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2230307 0.536 rs57637634 chr1:100447467 G/A cg24955406 chr1:100503596 HIAT1 0.59 5.94 0.31 7.19e-9 Carotid intima media thickness; LIHC cis rs2439831 0.850 rs8032649 chr15:44134922 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.61 -8.49 -0.42 6.57e-16 Lung cancer in ever smokers; LIHC cis rs56235845 0.964 rs11741640 chr5:176792743 G/A cg05207973 chr5:176823642 SLC34A1 0.34 5.93 0.31 7.41e-9 Hemoglobin concentration;Hematocrit; LIHC cis rs11581903 0.568 rs11205977 chr1:53068093 G/T cg19751897 chr1:52520827 TXNDC12;BTF3L4 0.8 5.99 0.31 5.34e-9 Joint mobility (Beighton score); LIHC trans rs11724903 0.935 rs7437074 chr4:183219488 G/A cg16239906 chr20:35724590 RBL1 -0.62 -6.08 -0.31 3.24e-9 Smoking initiation; LIHC cis rs2506889 0.553 rs7548453 chr1:10589836 A/G cg17425144 chr1:10567563 PEX14 0.49 9.71 0.46 7.58e-20 Breast cancer; LIHC cis rs1997103 1.000 rs1965556 chr7:55403584 C/G cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs35306767 0.953 rs11253509 chr10:964306 C/T cg20503657 chr10:835505 NA 0.89 10.61 0.5 6.2e-23 Eosinophil percentage of granulocytes; LIHC cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg27286337 chr10:134555280 INPP5A -0.89 -12.9 -0.57 2.65e-31 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7223966 0.655 rs9896476 chr17:61629692 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.54 -5.77 -0.3 1.8e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs950169 0.887 rs220333 chr15:85091133 C/T cg17507749 chr15:85114479 UBE2QP1 0.75 8.63 0.42 2.33e-16 Schizophrenia; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25001845 chr14:75201709 FCF1 0.39 6.14 0.32 2.33e-9 Immature fraction of reticulocytes; LIHC cis rs2066819 1.000 rs76430365 chr12:56699993 A/C cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg03188948 chr7:1209495 NA 0.78 6.17 0.32 1.89e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs344364 0.511 rs2982433 chr16:1954508 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.52 -6.85 -0.35 3.35e-11 Glomerular filtration rate in chronic kidney disease; LIHC cis rs72781680 0.706 rs72794290 chr2:23896106 A/T cg08917208 chr2:24149416 ATAD2B 1.0 8.35 0.41 1.7e-15 Lymphocyte counts; LIHC cis rs17376456 0.757 rs1031424 chr5:93139706 G/C cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs7039377 0.554 rs12351753 chr9:38673105 C/G cg14625731 chr9:38672608 NA -0.47 -7.57 -0.38 3.4e-13 Obesity-related traits; LIHC cis rs7615952 0.799 rs13315434 chr3:125641394 T/G cg05084668 chr3:125655381 ALG1L -0.6 -8.83 -0.43 5.43e-17 Blood pressure (smoking interaction); LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.13 0.4 7.79e-15 Height; LIHC cis rs6754311 0.593 rs55825471 chr2:136526981 T/A cg15123519 chr2:136567270 LCT 0.45 8.83 0.43 5.46e-17 Mosquito bite size; LIHC cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg05552183 chr6:42928497 GNMT -0.44 -6.48 -0.33 3.15e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7131987 0.845 rs2042511 chr12:29408780 C/T cg12903224 chr12:29470962 FAR2 -0.42 -6.73 -0.34 7.04e-11 QT interval; LIHC cis rs2070488 0.965 rs7433277 chr3:38529818 C/T cg24069376 chr3:38537580 EXOG 0.43 8.02 0.4 1.74e-14 Electrocardiographic conduction measures; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04849995 chr17:66016719 NA 0.42 6.1 0.31 2.92e-9 Pancreatic cancer; LIHC cis rs8016982 0.674 rs2288499 chr14:81660997 C/T cg01989461 chr14:81687754 GTF2A1 0.7 14.52 0.62 1.54e-37 Schizophrenia; LIHC cis rs2204008 0.807 rs4123933 chr12:37973539 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs2842992 1.000 rs2758322 chr6:160075188 G/T cg11366901 chr6:160182831 ACAT2 0.89 14.04 0.6 1.15e-35 Age-related macular degeneration (geographic atrophy); LIHC cis rs6594499 0.872 rs6859041 chr5:110435231 G/A cg04022379 chr5:110408740 TSLP 0.49 8.25 0.41 3.52e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1494950 0.661 rs1908446 chr4:15002784 C/T cg12377275 chr4:15005593 CPEB2 -0.83 -7.36 -0.37 1.35e-12 Political ideology; LIHC cis rs929354 0.713 rs7798816 chr7:156940574 A/G cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg24549020 chr5:56110836 MAP3K1 0.48 6.32 0.32 8.08e-10 Initial pursuit acceleration; LIHC trans rs983392 0.709 rs11230194 chr11:59980315 C/G cg17275991 chr19:58003312 ZNF419 0.44 6.26 0.32 1.12e-9 Alzheimer's disease (late onset); LIHC trans rs7618501 1.000 rs9859153 chr3:49807085 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.81 15.13 0.63 6.04e-40 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.953 rs11253521 chr10:976416 G/C cg20503657 chr10:835505 NA 0.89 10.8 0.5 1.32e-23 Eosinophil percentage of granulocytes; LIHC cis rs12602486 1.000 rs76971031 chr17:42242724 T/G cg08193365 chr17:42277699 NA 1.05 7.39 0.37 1.16e-12 Glycated hemoglobin levels; LIHC cis rs6867032 0.876 rs1552435 chr5:2018378 A/G cg26168224 chr5:2018326 NA 0.3 7.27 0.37 2.46e-12 Gut microbiome composition (winter); LIHC cis rs17253792 0.749 rs79713967 chr14:56124186 T/C cg01858014 chr14:56050164 KTN1 -0.71 -7.22 -0.36 3.38e-12 Putamen volume; LIHC cis rs13223928 0.651 rs4722435 chr7:3152962 C/T cg19214707 chr7:3157722 NA 0.44 8.33 0.41 1.99e-15 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs6570726 0.577 rs399502 chr6:145805874 A/G cg13319975 chr6:146136371 FBXO30 -0.59 -8.63 -0.42 2.41e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.964 rs778721 chr7:65845397 C/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs6570726 0.599 rs4398765 chr6:145935006 C/A cg13319975 chr6:146136371 FBXO30 -0.59 -8.84 -0.43 5.05e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg03517284 chr6:25882590 NA -1.08 -16.93 -0.68 3.93e-47 Urate levels; LIHC cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.46 0.33 3.68e-10 Schizophrenia; LIHC cis rs858239 0.601 rs2141307 chr7:23191424 G/C cg18081818 chr7:23246105 NA -0.4 -5.9 -0.3 8.69e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs990171 0.506 rs2041748 chr2:102756295 A/G cg22835712 chr2:102737379 NA 0.57 8.89 0.43 3.55e-17 Lymphocyte counts; LIHC cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg18230493 chr5:56204884 C5orf35 -0.41 -5.72 -0.3 2.27e-8 Initial pursuit acceleration; LIHC cis rs763121 0.819 rs4560233 chr22:38982442 A/T cg06022373 chr22:39101656 GTPBP1 0.66 11.28 0.52 2.74e-25 Menopause (age at onset); LIHC cis rs9926296 0.656 rs11861084 chr16:89875710 G/T cg04287289 chr16:89883240 FANCA -0.49 -7.88 -0.39 4.37e-14 Vitiligo; LIHC cis rs875971 0.508 rs6947808 chr7:66045082 A/G cg11764359 chr7:65958608 NA -0.62 -9.49 -0.46 4.2e-19 Aortic root size; LIHC cis rs17685 0.753 rs6951808 chr7:75772413 A/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs910316 1.000 rs13099 chr14:75599155 G/A cg08847533 chr14:75593920 NEK9 -0.88 -18.95 -0.72 2.93e-55 Height; LIHC cis rs2257205 0.667 rs7209498 chr17:56680642 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.86 0.39 5.22e-14 Pancreatic cancer; LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg18538332 chr22:24372958 LOC391322 -0.63 -9.21 -0.45 3.46e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11122272 0.735 rs2808603 chr1:231537738 T/C cg06096015 chr1:231504339 EGLN1 0.49 9.09 0.44 8.42e-18 Hemoglobin concentration; LIHC cis rs12431939 1.000 rs12432466 chr14:51638873 T/C cg23942311 chr14:51606299 NA -0.36 -6.06 -0.31 3.58e-9 Cancer; LIHC cis rs8072100 0.967 rs9894905 chr17:45485982 C/T cg25173405 chr17:45401733 C17orf57 -0.42 -5.83 -0.3 1.32e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2439831 0.867 rs2255051 chr15:43846161 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.69 11.02 0.51 2.24e-24 Lung cancer in ever smokers; LIHC cis rs74181299 0.819 rs2252867 chr2:65296280 T/C cg05010058 chr2:65284262 CEP68 0.39 6.61 0.34 1.5e-10 Pulse pressure; LIHC cis rs709400 0.628 rs1951392 chr14:103853367 T/G cg26031613 chr14:104095156 KLC1 0.78 9.78 0.47 4.48e-20 Body mass index; LIHC cis rs4925386 0.840 rs6143024 chr20:60914229 A/G cg24112000 chr20:60950667 NA -0.48 -6.5 -0.33 2.88e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7772486 0.754 rs9399567 chr6:146147295 C/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.48 -0.33 3.22e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4555082 0.874 rs28822720 chr14:105746282 T/C cg10792982 chr14:105748885 BRF1 0.44 5.99 0.31 5.34e-9 Mean platelet volume;Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00402069 chr5:89770788 POLR3G;MBLAC2 0.4 6.09 0.31 2.96e-9 Lung function (FEV1/FVC); LIHC cis rs875971 0.792 rs6971752 chr7:65737986 G/A cg18252515 chr7:66147081 NA 0.45 6.37 0.33 6.18e-10 Aortic root size; LIHC cis rs2404602 0.583 rs12908334 chr15:76581592 C/T cg23625390 chr15:77176239 SCAPER 0.34 5.91 0.3 8.37e-9 Blood metabolite levels; LIHC cis rs13108904 0.557 rs1680041 chr4:1238521 C/T cg02475777 chr4:1388615 CRIPAK -0.49 -7.36 -0.37 1.35e-12 Obesity-related traits; LIHC cis rs2072438 0.503 rs10739590 chr9:123871481 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 6.1 0.31 2.94e-9 Rheumatoid arthritis; LIHC cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.26 0.52 3.09e-25 Colorectal cancer; LIHC cis rs875971 0.638 rs801216 chr7:66011667 T/C cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs7927592 0.913 rs10896338 chr11:68299360 G/A cg20283391 chr11:68216788 NA -0.52 -7.8 -0.39 7.74e-14 Total body bone mineral density; LIHC cis rs2404602 0.684 rs157759 chr15:76846990 T/A cg23625390 chr15:77176239 SCAPER 0.52 8.59 0.42 3.13e-16 Blood metabolite levels; LIHC cis rs11688816 0.904 rs2539984 chr2:63133584 G/C cg17519650 chr2:63277830 OTX1 0.38 5.87 0.3 1.02e-8 Body mass index; LIHC cis rs798554 0.759 rs1182189 chr7:2869522 G/A cg04166393 chr7:2884313 GNA12 0.46 5.9 0.3 8.84e-9 Height; LIHC cis rs4243830 1.000 rs11809957 chr1:6584420 C/A cg22792644 chr1:6614718 TAS1R1;NOL9 0.78 7.63 0.38 2.3e-13 Body mass index; LIHC cis rs1008375 0.966 rs3775924 chr4:17585984 T/C cg02297831 chr4:17616191 MED28 0.48 7.33 0.37 1.68e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 0.901 rs13237344 chr7:66022256 T/A cg12463550 chr7:65579703 CRCP 0.67 6.9 0.35 2.49e-11 Diabetic kidney disease; LIHC cis rs1707322 0.638 rs1416706 chr1:46602844 G/A cg03146154 chr1:46216737 IPP -0.41 -6.25 -0.32 1.2e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7116495 1.000 rs495567 chr11:71795488 C/T cg26138937 chr11:71823887 C11orf51 -0.68 -6.84 -0.35 3.56e-11 Severe influenza A (H1N1) infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13794888 chr15:75917792 SNUPN 0.47 7.48 0.37 6.48e-13 Pancreatic cancer; LIHC cis rs9911578 1.000 rs8067571 chr17:56868856 C/T cg12560992 chr17:57184187 TRIM37 0.97 17.46 0.69 2.94e-49 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05909891 chr12:19565983 NA 0.44 6.53 0.33 2.45e-10 Hepatitis; LIHC cis rs1400745 0.718 rs799681 chr14:35350579 A/G cg16230307 chr14:35515116 FAM177A1 0.39 6.25 0.32 1.24e-9 Monocyte count; LIHC cis rs2576037 0.796 rs2571018 chr18:44585344 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.44 -6.51 -0.33 2.76e-10 Personality dimensions; LIHC cis rs17776563 0.887 rs72761998 chr15:89125207 G/T cg05013243 chr15:89149849 MIR1179 0.4 6.55 0.33 2.05e-10 Thyroid hormone levels; LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg06420487 chr17:61919686 SMARCD2 0.42 5.78 0.3 1.69e-8 Height; LIHC cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg27297192 chr10:134578999 INPP5A 0.53 7.06 0.36 9.16e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1801251 1.000 rs3816334 chr2:233708806 A/G cg25237894 chr2:233734115 C2orf82 -0.58 -11.39 -0.52 1.1e-25 Coronary artery disease; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg16145915 chr7:1198662 ZFAND2A -0.44 -12.29 -0.55 5.18e-29 Longevity;Endometriosis; LIHC cis rs6952808 0.600 rs2895202 chr7:2131829 T/C cg20295408 chr7:1910781 MAD1L1 -0.42 -6.05 -0.31 3.86e-9 Bipolar disorder and schizophrenia; LIHC cis rs72781680 0.821 rs1022346 chr2:24127849 T/C cg08917208 chr2:24149416 ATAD2B 0.64 6.44 0.33 4.1e-10 Lymphocyte counts; LIHC cis rs2439831 0.850 rs12442129 chr15:44055856 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.4 0.33 5.2e-10 Lung cancer in ever smokers; LIHC cis rs1707322 1.000 rs34444543 chr1:46358862 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.13 0.31 2.48e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7659604 0.676 rs6534323 chr4:122695888 G/A cg20573242 chr4:122745356 CCNA2 0.5 7.35 0.37 1.43e-12 Type 2 diabetes; LIHC cis rs6964587 0.610 rs6950682 chr7:91464218 G/T cg17063962 chr7:91808500 NA 0.63 10.84 0.51 1.01e-23 Breast cancer; LIHC cis rs8060686 0.623 rs6499157 chr16:68105474 A/C cg05110241 chr16:68378359 PRMT7 -0.49 -5.97 -0.31 5.84e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg10360323 chr17:41437877 NA 0.41 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs1113500 0.862 rs3853494 chr1:108637334 G/A cg06207961 chr1:108661230 NA 0.38 7.38 0.37 1.2e-12 Growth-regulated protein alpha levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23099349 chr6:26032281 HIST1H3B 0.4 6.76 0.34 5.93e-11 Cognitive function; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg18954051 chr12:66554863 TMBIM4 0.34 6.04 0.31 4.06e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2629540 0.793 rs10794180 chr10:126449306 T/A cg08799069 chr10:126477246 METTL10 -0.53 -8.56 -0.42 3.78e-16 Cocaine dependence; LIHC cis rs10744422 1.000 rs12255 chr12:123350204 C/T cg07706471 chr12:123319906 HIP1R -0.58 -7.47 -0.37 6.97e-13 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00473112 chr11:507177 RNH1 0.39 6.36 0.33 6.44e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9583531 0.628 rs9521914 chr13:111382231 C/A cg24331049 chr13:111365604 ING1 0.62 10.13 0.48 2.86e-21 Coronary artery disease; LIHC trans rs1499614 1.000 rs2707840 chr7:66158015 C/T cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg05368731 chr17:41323189 NBR1 0.74 12.71 0.57 1.4e-30 Menopause (age at onset); LIHC cis rs2841277 0.738 rs1036713 chr14:105396693 C/G cg15352829 chr14:105391018 PLD4 0.39 7.24 0.36 3e-12 Rheumatoid arthritis; LIHC cis rs5753037 0.543 rs140128 chr22:30150140 T/C cg01021169 chr22:30184971 ASCC2 -0.32 -5.92 -0.3 7.79e-9 Type 1 diabetes; LIHC cis rs9378688 0.654 rs11242758 chr6:2362266 A/G cg12303981 chr6:2244766 GMDS 0.44 6.02 0.31 4.46e-9 Caudate nucleus volume; LIHC cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 11.46 0.53 5.76e-26 Platelet count; LIHC cis rs2204008 0.575 rs10444564 chr12:38043782 T/C cg26384229 chr12:38710491 ALG10B 0.85 10.57 0.5 9e-23 Bladder cancer; LIHC cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg16049864 chr8:95962084 TP53INP1 -0.63 -11.85 -0.54 2.23e-27 Type 2 diabetes; LIHC cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg18306943 chr3:40428807 ENTPD3 0.35 6.01 0.31 4.63e-9 Renal cell carcinoma; LIHC trans rs7615952 0.673 rs35001498 chr3:125628644 A/G cg07211511 chr3:129823064 LOC729375 -0.83 -8.78 -0.43 7.86e-17 Blood pressure (smoking interaction); LIHC cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg21782813 chr7:2030301 MAD1L1 0.48 8.29 0.41 2.71e-15 Bipolar disorder and schizophrenia; LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg06656553 chr16:89960601 TCF25 -0.46 -5.81 -0.3 1.47e-8 Skin colour saturation; LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.19 0.55 1.2e-28 Height; LIHC cis rs138880 0.580 rs28562884 chr22:50312869 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.83 -7.19 -0.36 4.09e-12 Schizophrenia; LIHC cis rs2742540 0.503 rs7106539 chr11:8897533 T/G cg12365402 chr11:9010492 NRIP3 -0.25 -5.97 -0.31 5.92e-9 Hematocrit; LIHC cis rs9768139 0.733 rs13309363 chr7:158122179 C/A cg25566285 chr7:158114605 PTPRN2 0.23 6.25 0.32 1.19e-9 Calcium levels; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg02990361 chr1:107599529 PRMT6 -0.66 -11.05 -0.51 1.78e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10791097 0.703 rs11222360 chr11:130730871 C/T cg14779329 chr11:130786720 SNX19 0.38 5.99 0.31 5.25e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11690935 0.959 rs4668412 chr2:172619770 A/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.53 -0.69 1.51e-49 Schizophrenia; LIHC cis rs2645694 0.603 rs2703123 chr4:77821154 C/T cg03477792 chr4:77819574 ANKRD56 0.61 8.86 0.43 4.39e-17 Emphysema distribution in smoking; LIHC trans rs3780486 0.846 rs3780490 chr9:33129839 A/G cg04842962 chr6:43655489 MRPS18A 1.08 26.07 0.82 2.79e-83 IgG glycosylation; LIHC cis rs892961 1.000 rs1075457 chr17:75400737 A/G cg05865280 chr17:75406074 SEPT9 -0.54 -10.81 -0.5 1.28e-23 Airflow obstruction; LIHC cis rs35110281 0.594 rs230641 chr21:44915441 T/C cg21573476 chr21:45109991 RRP1B 0.45 8.33 0.41 1.93e-15 Mean corpuscular volume; LIHC trans rs877282 1.000 rs34257857 chr10:772993 C/A cg22713356 chr15:30763199 NA 1.23 10.89 0.51 6.83e-24 Uric acid levels; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs8084351 0.582 rs7505556 chr18:50571419 A/G cg24270629 chr18:50823537 DCC 0.39 6.04 0.31 4.06e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7131987 0.903 rs10843367 chr12:29408380 G/A cg12903224 chr12:29470962 FAR2 -0.41 -6.45 -0.33 3.89e-10 QT interval; LIHC cis rs5769765 0.955 rs8139758 chr22:50261123 G/T cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs7945718 0.621 rs4370915 chr11:12664998 C/T cg25843174 chr11:12811716 TEAD1 0.32 7.26 0.37 2.65e-12 Educational attainment (years of education); LIHC cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.06 0.31 3.68e-9 Menopause (age at onset); LIHC cis rs9916302 0.904 rs1966916 chr17:37425238 T/G cg00129232 chr17:37814104 STARD3 -0.39 -6.33 -0.32 7.5e-10 Glomerular filtration rate (creatinine); LIHC cis rs7107174 1.000 rs2511186 chr11:77984306 C/G cg02023728 chr11:77925099 USP35 0.49 9.45 0.46 5.4e-19 Testicular germ cell tumor; LIHC cis rs68170813 0.559 rs75313693 chr7:106863170 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs7208859 0.623 rs8081299 chr17:29104296 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.19 0.41 5.17e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7208859 0.623 rs77009951 chr17:29080650 T/C cg13385521 chr17:29058706 SUZ12P 0.81 7.96 0.4 2.61e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8180040 0.654 rs6791062 chr3:47174343 T/A cg27129171 chr3:47204927 SETD2 0.57 9.46 0.46 5.2e-19 Colorectal cancer; LIHC cis rs74233809 0.901 rs4409766 chr10:104616663 A/G cg03493300 chr10:104813866 CNNM2 0.42 5.81 0.3 1.43e-8 Birth weight; LIHC cis rs763121 0.815 rs12168758 chr22:38997269 C/G cg06022373 chr22:39101656 GTPBP1 0.65 12.73 0.57 1.23e-30 Menopause (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01519350 chr3:137906342 ARMC8 0.42 6.78 0.34 5.4e-11 Cognitive function; LIHC cis rs780096 0.546 rs715326 chr2:27725761 A/G cg05484376 chr2:27715224 FNDC4 -0.33 -5.74 -0.3 2.13e-8 Total body bone mineral density; LIHC cis rs9596863 0.898 rs9568917 chr13:54351040 G/A ch.13.53330881F chr13:54432880 NA 0.45 6.06 0.31 3.57e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2354432 0.660 rs10751415 chr1:146830785 T/A cg25205988 chr1:146714368 CHD1L 0.83 9.53 0.46 3.06e-19 Mitochondrial DNA levels; LIHC cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 9.27 0.45 2.08e-18 Platelet count; LIHC cis rs600806 0.751 rs7551176 chr1:109961965 C/T cg23091122 chr1:110024289 SYPL2 -0.46 -6.09 -0.31 2.96e-9 Intelligence (multi-trait analysis); LIHC cis rs943466 1.000 rs943461 chr6:33769409 C/G cg25922239 chr6:33757077 LEMD2 -0.5 -6.41 -0.33 4.91e-10 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs2404602 0.692 rs12910734 chr15:77149931 A/G cg03037974 chr15:76606532 NA 0.74 14.5 0.62 1.73e-37 Blood metabolite levels; LIHC cis rs9896052 0.534 rs8065160 chr17:73441090 A/G cg25649188 chr17:73499917 CASKIN2 -0.43 -6.95 -0.35 1.87e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs7607369 0.637 rs3888879 chr2:219290676 C/T cg02176678 chr2:219576539 TTLL4 -0.52 -6.92 -0.35 2.26e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7903847 0.642 rs11817875 chr10:99158414 G/A cg06359132 chr10:99160096 RRP12 -0.42 -6.37 -0.33 5.93e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9457247 0.765 rs10484531 chr6:167454434 G/A cg12798992 chr6:167411361 FGFR1OP 0.48 7.18 0.36 4.46e-12 Crohn's disease; LIHC cis rs1023500 0.551 rs2301521 chr22:42423110 G/C cg15557168 chr22:42548783 NA -0.45 -6.7 -0.34 8.64e-11 Schizophrenia; LIHC cis rs7412746 0.658 rs10305704 chr1:150804429 A/C cg17724175 chr1:150552817 MCL1 0.47 9.35 0.45 1.19e-18 Melanoma; LIHC cis rs922107 0.713 rs6680212 chr1:90045922 C/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.73 -0.39 1.19e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7572733 0.534 rs1401091 chr2:198790423 T/G cg10820045 chr2:198174542 NA -0.48 -7.22 -0.36 3.31e-12 Dermatomyositis; LIHC cis rs644799 1.000 rs12291986 chr11:95523030 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.93 17.31 0.68 1.13e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7945718 1.000 rs12269900 chr11:12748518 G/A cg25843174 chr11:12811716 TEAD1 0.36 8.21 0.41 4.7e-15 Educational attainment (years of education); LIHC cis rs9640161 0.830 rs76741564 chr7:150059529 A/T cg10018233 chr7:150070692 REPIN1 0.67 12.31 0.55 4.37e-29 Blood protein levels;Circulating chemerin levels; LIHC cis rs7903847 0.642 rs10786341 chr10:99158607 G/A cg08345082 chr10:99160200 RRP12 -0.4 -6.66 -0.34 1.12e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg25894440 chr7:65020034 NA 0.52 6.05 0.31 3.73e-9 Diabetic kidney disease; LIHC cis rs2629540 0.924 rs2629541 chr10:126425866 G/A cg08799069 chr10:126477246 METTL10 0.46 7.18 0.36 4.42e-12 Cocaine dependence; LIHC cis rs797680 0.856 rs2765545 chr1:93677269 G/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.65e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs7474896 0.616 rs2474561 chr10:38373544 C/T cg00409905 chr10:38381863 ZNF37A -0.49 -6.85 -0.35 3.49e-11 Obesity (extreme); LIHC cis rs722599 0.748 rs2300599 chr14:75359441 A/G cg11812906 chr14:75593930 NEK9 -0.48 -7.73 -0.39 1.2e-13 IgG glycosylation; LIHC cis rs4665809 1.000 rs750451 chr2:26324241 G/A cg27170947 chr2:26402098 FAM59B -0.66 -8.3 -0.41 2.37e-15 Gut microbiome composition (summer); LIHC cis rs875971 0.862 rs1860469 chr7:66106875 A/G cg11764359 chr7:65958608 NA -0.71 -11.86 -0.54 2.06e-27 Aortic root size; LIHC trans rs1499614 0.803 rs1796229 chr7:66119661 G/A cg07424592 chr7:64974309 NA 0.78 8.92 0.43 2.85e-17 Gout; LIHC cis rs546131 1.000 rs546131 chr11:34851760 G/C cg06937548 chr11:34938143 PDHX;APIP 0.56 7.74 0.39 1.16e-13 Lung disease severity in cystic fibrosis; LIHC cis rs801193 1.000 rs4279493 chr7:66226620 C/T cg11764359 chr7:65958608 NA 0.71 10.63 0.5 5.5e-23 Aortic root size; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.28 0.55 5.92e-29 Prudent dietary pattern; LIHC cis rs4638749 0.677 rs7595399 chr2:108835943 C/G cg06795125 chr2:108905320 SULT1C2 -0.3 -6.02 -0.31 4.52e-9 Blood pressure; LIHC cis rs7769051 1.000 rs10484629 chr6:133117870 A/C cg07930552 chr6:133119739 C6orf192 0.75 7.02 0.35 1.2e-11 Type 2 diabetes nephropathy; LIHC cis rs8180040 0.966 rs13059519 chr3:47539969 C/T cg27129171 chr3:47204927 SETD2 0.6 10.34 0.49 5.69e-22 Colorectal cancer; LIHC cis rs9640161 0.789 rs1464753 chr7:150021350 G/C cg21361702 chr7:150065534 REPIN1 0.44 5.99 0.31 5.31e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs992157 0.798 rs10206064 chr2:219157959 T/C cg00012203 chr2:219082015 ARPC2 0.85 13.77 0.6 1.22e-34 Colorectal cancer; LIHC cis rs1555322 0.530 rs2425042 chr20:33865895 G/A cg08210727 chr20:33865349 NA 0.5 5.77 0.3 1.76e-8 Attention deficit hyperactivity disorder; LIHC cis rs921968 0.541 rs599973 chr2:219387273 C/G cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs6733011 0.628 rs981602 chr2:99464275 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.41 -5.81 -0.3 1.47e-8 Bipolar disorder; LIHC cis rs1801251 1.000 rs6747645 chr2:233571033 C/T cg08000102 chr2:233561755 GIGYF2 -0.75 -11.77 -0.54 4.37e-27 Coronary artery disease; LIHC cis rs11997175 0.569 rs36034014 chr8:33814219 G/A ch.8.33884649F chr8:33765107 NA -0.4 -6.54 -0.33 2.28e-10 Body mass index; LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs7224737 1.000 rs12603330 chr17:40290589 T/A cg00647820 chr17:40259828 DHX58 -0.28 -5.94 -0.31 7.08e-9 Fibrinogen levels; LIHC cis rs875971 1.000 rs35149210 chr7:65929925 T/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs172166 0.652 rs476167 chr6:28065888 T/C cg16479474 chr6:28041457 NA 0.39 6.68 0.34 9.59e-11 Cardiac Troponin-T levels; LIHC cis rs11112613 0.713 rs73184083 chr12:105952593 T/A cg03607813 chr12:105948248 NA 0.63 12.47 0.56 1.14e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs4969178 0.930 rs4580257 chr17:76403028 T/G cg20026190 chr17:76395443 PGS1 0.45 7.1 0.36 7.45e-12 HDL cholesterol levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22554796 chr10:32345272 KIF5B 0.46 6.42 0.33 4.62e-10 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg11764359 chr7:65958608 NA 0.6 6.38 0.33 5.71e-10 Diabetic kidney disease; LIHC cis rs11864453 0.647 rs10492813 chr16:72122463 A/G cg16558253 chr16:72132732 DHX38 0.43 7.14 0.36 5.56e-12 Fibrinogen levels; LIHC cis rs6665290 0.901 rs3795453 chr1:227205331 A/G cg10327440 chr1:227177885 CDC42BPA -1.13 -22.78 -0.78 1.48e-70 Myeloid white cell count; LIHC cis rs1552244 0.572 rs68121641 chr3:10165845 T/A cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs68170813 0.559 rs12536574 chr7:106810997 A/T cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs7412746 0.658 rs11204723 chr1:150731618 T/C cg17724175 chr1:150552817 MCL1 0.48 9.3 0.45 1.65e-18 Melanoma; LIHC cis rs1008375 1.000 rs10939740 chr4:17617490 T/C cg02297831 chr4:17616191 MED28 0.42 5.91 0.3 8.49e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs757110 0.770 rs11024271 chr11:17395540 T/C cg15432903 chr11:17409602 KCNJ11 0.66 10.18 0.48 1.95e-21 Type 2 diabetes; LIHC cis rs2274273 0.870 rs4366639 chr14:55790516 T/G cg01864836 chr14:55583639 NA -0.37 -6.57 -0.33 1.9e-10 Protein biomarker; LIHC cis rs3806843 0.648 rs2530233 chr5:140082876 A/G cg19875535 chr5:140030758 IK -0.41 -6.6 -0.34 1.57e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.83 0.3 1.31e-8 Menopause (age at onset); LIHC trans rs35365539 1 rs35365539 chr3:49794347 A/AC cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Blood protein levels; LIHC trans rs459571 0.959 rs2073818 chr9:136918662 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.56 -8.54 -0.42 4.63e-16 Platelet distribution width; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg09260627 chr8:8243751 NA 0.67 6.11 0.31 2.71e-9 Musician's dystonia; LIHC cis rs8180040 0.726 rs7610636 chr3:47064436 A/C cg16586182 chr3:47516702 SCAP 0.47 8.47 0.42 7.22e-16 Colorectal cancer; LIHC cis rs174601 0.833 rs174541 chr11:61565908 T/C cg27386326 chr11:61587980 NA 0.69 14.74 0.62 2.09e-38 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC trans rs8073060 0.586 rs7214250 chr17:33981704 C/G cg19694781 chr19:47549865 TMEM160 -1.27 -13.8 -0.6 9.37e-35 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6835098 1.000 rs2332654 chr4:174088399 C/T cg27433088 chr4:174089019 GALNT7 0.4 7.32 0.37 1.81e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs3008870 0.920 rs2755253 chr1:67470843 C/T cg02640540 chr1:67518911 SLC35D1 0.49 7.36 0.37 1.35e-12 Lymphocyte percentage of white cells; LIHC cis rs6964587 0.692 rs4729025 chr7:91847504 C/T cg17063962 chr7:91808500 NA 0.69 12.34 0.56 3.46e-29 Breast cancer; LIHC cis rs1882538 0.504 rs6951416 chr7:133092278 A/G cg10665199 chr7:133106180 EXOC4 0.5 8.19 0.41 5.08e-15 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs2808585 chr1:231514218 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.56 -0.5 9.46e-23 Hemoglobin concentration; LIHC cis rs7089973 0.604 rs7903663 chr10:116609904 G/A cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9314323 0.798 rs12682345 chr8:26218332 A/G cg13160058 chr8:26243215 BNIP3L 0.39 6.98 0.35 1.5e-11 Red cell distribution width; LIHC cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg17971929 chr21:40555470 PSMG1 0.86 10.31 0.49 7.18e-22 Cognitive function; LIHC cis rs9303280 0.806 rs35736272 chr17:38032680 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.77 0.3 1.76e-8 Self-reported allergy; LIHC cis rs870825 0.860 rs72689277 chr4:185593699 G/A cg04058563 chr4:185651563 MLF1IP 0.86 7.3 0.37 1.99e-12 Blood protein levels; LIHC cis rs3892630 0.878 rs1061686 chr19:33204544 C/T cg22980127 chr19:33182716 NUDT19 -0.88 -10.46 -0.49 2.14e-22 Red blood cell traits; LIHC cis rs7131987 0.650 rs7957339 chr12:29456495 T/C cg12903224 chr12:29470962 FAR2 -0.4 -6.59 -0.34 1.63e-10 QT interval; LIHC cis rs12479064 0.694 rs11896520 chr2:99995517 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.64 -6.86 -0.35 3.3e-11 Chronic sinus infection; LIHC cis rs7772486 0.738 rs75288066 chr6:146319386 C/A cg13319975 chr6:146136371 FBXO30 -0.44 -7.0 -0.35 1.37e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1865760 1.000 rs7770139 chr6:25925823 A/G cg03517284 chr6:25882590 NA -0.38 -5.74 -0.3 2.06e-8 Height; LIHC trans rs2073499 0.873 rs6446202 chr3:50219991 C/G cg21659725 chr3:3221576 CRBN 0.68 8.03 0.4 1.63e-14 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26670552 chr16:69600032 NFAT5;MIR1538 0.44 6.26 0.32 1.16e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs67460515 0.563 rs4679672 chr3:160901020 G/A cg17135325 chr3:160939158 NMD3 0.6 8.9 0.43 3.23e-17 Parkinson's disease; LIHC cis rs9517313 0.591 rs9554480 chr13:99221138 T/A cg07423050 chr13:99094983 FARP1 -0.47 -8.03 -0.4 1.6e-14 Neuroticism; LIHC cis rs4919694 1.000 rs58317752 chr10:104799267 T/A cg04362960 chr10:104952993 NT5C2 1.14 8.88 0.43 3.89e-17 Arsenic metabolism; LIHC cis rs644799 0.710 rs473852 chr11:95568757 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.78 12.17 0.55 1.53e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs798554 0.757 rs1182198 chr7:2862906 C/T cg04166393 chr7:2884313 GNA12 0.49 6.43 0.33 4.29e-10 Height; LIHC cis rs6545883 0.860 rs6749226 chr2:61509783 G/A cg14146966 chr2:61757674 XPO1 -0.43 -7.24 -0.36 2.99e-12 Tuberculosis; LIHC cis rs3008870 1.000 rs2755256 chr1:67471692 A/T cg02640540 chr1:67518911 SLC35D1 0.44 6.06 0.31 3.5e-9 Lymphocyte percentage of white cells; LIHC cis rs7617773 0.539 rs6779517 chr3:48384388 C/T cg11946769 chr3:48343235 NME6 0.59 7.28 0.37 2.27e-12 Coronary artery disease; LIHC cis rs11758351 0.866 rs2022448 chr6:26207928 C/T cg03854865 chr6:26224070 HIST1H3E 0.51 6.36 0.33 6.42e-10 Gout;Renal underexcretion gout; LIHC cis rs7246657 1.000 rs10426297 chr19:37798373 A/G cg23950597 chr19:37808831 NA -0.5 -6.36 -0.33 6.62e-10 Coronary artery calcification; LIHC trans rs2243480 0.711 rs2420172 chr7:65635341 T/C cg10756647 chr7:56101905 PSPH -1.08 -13.26 -0.58 1.18e-32 Diabetic kidney disease; LIHC trans rs7615952 0.932 rs11922218 chr3:125631289 C/T cg07211511 chr3:129823064 LOC729375 -0.84 -10.48 -0.49 1.75e-22 Blood pressure (smoking interaction); LIHC cis rs9354352 0.818 rs9453548 chr6:66691885 T/C cg07460842 chr6:66804631 NA -0.58 -9.12 -0.44 6.77e-18 Initial pursuit acceleration in psychotic disorders; LIHC cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg00149659 chr3:10157352 C3orf10 0.7 7.1 0.36 7.09e-12 Alzheimer's disease; LIHC cis rs6840360 0.571 rs4696278 chr4:152558978 A/G cg22705602 chr4:152727874 NA -0.32 -6.23 -0.32 1.38e-9 Intelligence (multi-trait analysis); LIHC cis rs1256061 0.603 rs1256038 chr14:64740739 T/C cg23250157 chr14:64679961 SYNE2 0.4 6.03 0.31 4.25e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09544279 chr5:179921349 CNOT6 -0.44 -6.92 -0.35 2.22e-11 Pancreatic cancer; LIHC cis rs2279817 0.743 rs12023874 chr1:18025612 A/G cg21791023 chr1:18019539 ARHGEF10L 0.41 6.31 0.32 8.89e-10 Neuroticism; LIHC cis rs2839186 0.843 rs17182671 chr21:47696238 T/C cg05896524 chr21:47604654 C21orf56 0.44 6.61 0.34 1.49e-10 Testicular germ cell tumor; LIHC cis rs1163251 0.729 rs686362 chr1:120221011 T/C cg19096424 chr1:120255104 PHGDH 0.49 6.09 0.31 3.06e-9 Blood metabolite levels; LIHC cis rs6952808 0.707 rs13244345 chr7:1973004 A/G cg20295408 chr7:1910781 MAD1L1 -0.49 -7.07 -0.36 8.54e-12 Bipolar disorder and schizophrenia; LIHC cis rs5769765 0.954 rs6009900 chr22:50236610 T/C cg26441486 chr22:50317300 CRELD2 0.36 6.14 0.32 2.24e-9 Schizophrenia; LIHC cis rs9733 0.596 rs12089989 chr1:150715782 G/A cg17724175 chr1:150552817 MCL1 0.44 8.99 0.44 1.75e-17 Tonsillectomy; LIHC cis rs10916814 0.632 rs10916819 chr1:20901000 A/G cg24502330 chr1:20914028 CDA -0.31 -6.8 -0.35 4.68e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg00035636 chr13:21900591 NA 0.4 6.8 0.35 4.65e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg11494091 chr17:61959527 GH2 0.36 5.99 0.31 5.44e-9 Height; LIHC cis rs7584330 0.554 rs9646713 chr2:238443542 T/C cg08992911 chr2:238395768 MLPH 0.5 6.01 0.31 4.86e-9 Prostate cancer; LIHC cis rs12220238 0.908 rs10824133 chr10:76020585 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.6 6.3 0.32 9e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs11958404 0.932 rs60504573 chr5:157436786 T/A cg05962755 chr5:157440814 NA 0.99 11.5 0.53 4.32e-26 IgG glycosylation; LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg07092213 chr7:1199455 ZFAND2A -0.43 -6.31 -0.32 8.57e-10 Longevity;Endometriosis; LIHC trans rs4906332 1.000 rs55731474 chr14:103878481 G/A cg17675199 chr6:35436792 RPL10A 0.3 6.13 0.31 2.45e-9 Coronary artery disease; LIHC cis rs60871478 0.704 rs62432895 chr7:822050 C/G cg13844804 chr7:814759 HEATR2 0.42 5.73 0.3 2.25e-8 Cerebrospinal P-tau181p levels; LIHC cis rs2073300 0.609 rs17757442 chr20:23421101 A/G cg12062639 chr20:23401060 NAPB -1.03 -13.39 -0.59 3.59e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7659604 0.592 rs56077950 chr4:122721412 C/T cg20573242 chr4:122745356 CCNA2 0.53 7.77 0.39 9.51e-14 Type 2 diabetes; LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg11494091 chr17:61959527 GH2 -0.35 -5.92 -0.3 7.95e-9 Height; LIHC cis rs6754311 0.513 rs1438304 chr2:136503157 A/G cg25344623 chr2:136566232 LCT 0.44 8.85 0.43 4.92e-17 Mosquito bite size; LIHC cis rs6967414 1.000 rs6967414 chr7:6749758 G/A cg00387323 chr7:6746715 ZNF12 0.62 7.07 0.36 8.81e-12 Hematocrit;Hemoglobin concentration; LIHC cis rs769267 0.965 rs7254230 chr19:19434350 C/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.39 -0.33 5.54e-10 Tonsillectomy; LIHC cis rs4819052 0.851 rs35871601 chr21:46675214 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.48 0.53 4.87e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg13395646 chr4:1353034 KIAA1530 -0.68 -10.04 -0.48 5.7e-21 Obesity-related traits; LIHC cis rs66569888 0.754 rs6719028 chr2:106895212 T/C cg00318621 chr2:106887213 NA 0.62 6.33 0.32 7.86e-10 Facial morphology (factor 23); LIHC cis rs9733 0.635 rs486836 chr1:150875967 A/T cg13175981 chr1:150552382 MCL1 0.5 7.08 0.36 8.44e-12 Tonsillectomy; LIHC cis rs67478160 0.619 rs2368560 chr14:104273311 C/T cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.23 -0.36 3.09e-12 Schizophrenia; LIHC cis rs7208859 0.623 rs8075341 chr17:29136565 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3736485 0.966 rs6493510 chr15:51900651 T/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1.01e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1005277 0.602 rs1831315 chr10:38473353 T/C cg17830980 chr10:43048298 ZNF37B -0.52 -10.08 -0.48 4.4e-21 Extrinsic epigenetic age acceleration; LIHC cis rs9457247 0.967 rs1211447 chr6:167381979 C/T cg23791538 chr6:167370224 RNASET2 -0.67 -11.63 -0.53 1.44e-26 Crohn's disease; LIHC cis rs2067615 0.579 rs10778510 chr12:107162965 A/G cg15890332 chr12:107067104 RFX4 -0.26 -6.21 -0.32 1.57e-9 Heart rate; LIHC cis rs778371 0.748 rs2675953 chr2:233749565 G/C cg08000102 chr2:233561755 GIGYF2 -0.85 -13.68 -0.59 2.8e-34 Schizophrenia; LIHC cis rs933688 1.000 rs7720132 chr5:90745105 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.2 0.66 3.29e-44 Smoking behavior; LIHC cis rs921968 0.565 rs11896209 chr2:219599268 C/T cg02985541 chr2:219472218 PLCD4 -0.38 -6.72 -0.34 7.62e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs1707322 0.752 rs3811436 chr1:46125880 T/C cg03146154 chr1:46216737 IPP 0.57 9.89 0.47 1.96e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17401966 1.000 rs35837142 chr1:10322358 C/G cg19773385 chr1:10388646 KIF1B -0.48 -8.19 -0.41 5.17e-15 Hepatocellular carcinoma; LIHC cis rs1577917 1.000 rs12661204 chr6:86678586 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.71 -0.34 8.08e-11 Response to antipsychotic treatment; LIHC cis rs7249142 0.549 rs10854012 chr19:19295719 C/T cg24446071 chr19:19281270 LOC729991-MEF2B;MEF2B -0.35 -5.81 -0.3 1.44e-8 IgG glycosylation; LIHC cis rs2073300 0.609 rs6132610 chr20:23403987 C/T cg12062639 chr20:23401060 NAPB 1.03 13.28 0.58 9.93e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs67460515 0.892 rs11718905 chr3:161051793 G/A cg17135325 chr3:160939158 NMD3 0.57 8.16 0.4 6.34e-15 Parkinson's disease; LIHC cis rs908922 0.676 rs7547628 chr1:152527738 T/C cg20991723 chr1:152506922 NA 0.49 8.25 0.41 3.57e-15 Hair morphology; LIHC cis rs13256369 0.708 rs10903310 chr8:8589687 A/C cg00074818 chr8:8560427 CLDN23 -0.39 -6.32 -0.32 8.12e-10 Obesity-related traits; LIHC cis rs9393692 0.905 rs6908328 chr6:26292855 C/A cg13736514 chr6:26305472 NA -0.38 -6.45 -0.33 3.77e-10 Educational attainment; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.28 0.55 6e-29 Prudent dietary pattern; LIHC trans rs2727020 0.558 rs1164675 chr11:49325972 C/T cg03929089 chr4:120376271 NA 0.75 13.03 0.58 8.69e-32 Coronary artery disease; LIHC cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg18279126 chr7:2041391 MAD1L1 0.39 6.58 0.33 1.82e-10 Bipolar disorder and schizophrenia; LIHC cis rs2066819 1.000 rs17118409 chr12:56630764 G/A cg26714650 chr12:56694279 CS -1.34 -12.2 -0.55 1.1e-28 Psoriasis vulgaris; LIHC cis rs2070488 0.965 rs1870915 chr3:38494228 G/C cg24069376 chr3:38537580 EXOG 0.43 8.04 0.4 1.48e-14 Electrocardiographic conduction measures; LIHC cis rs7534824 0.625 rs6686202 chr1:101493078 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.76 7.05 0.36 1.01e-11 Refractive astigmatism; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.39 -0.37 1.17e-12 Lymphocyte counts; LIHC cis rs10256972 0.967 rs1881122 chr7:1040946 A/T cg04025307 chr7:1156635 C7orf50 0.5 8.31 0.41 2.23e-15 Longevity;Endometriosis; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg09367891 chr1:107599246 PRMT6 0.7 11.72 0.54 6.82e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs427394 0.659 rs274725 chr5:6717408 C/G cg10857441 chr5:6722123 POLS -0.38 -6.37 -0.33 5.95e-10 Menopause (age at onset); LIHC cis rs8081395 0.836 rs1295926 chr17:57909373 A/G cg02344993 chr17:57696989 CLTC -0.45 -7.38 -0.37 1.25e-12 White blood cell count; LIHC cis rs4906332 0.782 rs12880224 chr14:104006414 C/G cg04998671 chr14:104000505 TRMT61A -0.56 -7.15 -0.36 5.42e-12 Coronary artery disease; LIHC cis rs1801251 1.000 rs12478564 chr2:233598340 C/T cg08000102 chr2:233561755 GIGYF2 0.76 11.45 0.53 6.36e-26 Coronary artery disease; LIHC cis rs757081 0.667 rs17641418 chr11:17161341 T/C cg15432903 chr11:17409602 KCNJ11 -0.42 -5.88 -0.3 9.7e-9 Systolic blood pressure; LIHC cis rs754466 0.914 rs12218917 chr10:79701479 C/T cg17075019 chr10:79541650 NA -0.58 -7.55 -0.38 4.12e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9868809 0.772 rs34096717 chr3:48719453 A/C cg07636037 chr3:49044803 WDR6 -0.62 -6.61 -0.34 1.46e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs2073499 1.000 rs6776145 chr3:50316119 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.91 -15.16 -0.63 4.42e-40 Schizophrenia; LIHC cis rs3204270 0.684 rs57405099 chr17:79637065 T/C cg18367735 chr17:79674897 NA 0.69 7.92 0.39 3.46e-14 Dental caries; LIHC cis rs858239 0.541 rs4624924 chr7:23168843 A/C cg23682824 chr7:23144976 KLHL7 0.42 6.27 0.32 1.06e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg12419862 chr22:24373484 LOC391322 -0.72 -11.01 -0.51 2.54e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs703842 0.585 rs10877022 chr12:58223937 A/G cg18357645 chr12:58087776 OS9 -0.42 -6.25 -0.32 1.25e-9 Multiple sclerosis; LIHC cis rs875971 0.502 rs2465121 chr7:65621004 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.36 -7.22 -0.36 3.3e-12 Aortic root size; LIHC cis rs9910055 0.529 rs228748 chr17:42174390 G/A cg19774624 chr17:42201019 HDAC5 0.51 6.24 0.32 1.3e-9 Total body bone mineral density; LIHC cis rs763121 0.853 rs2413544 chr22:39059404 A/C cg06022373 chr22:39101656 GTPBP1 0.66 11.49 0.53 4.72e-26 Menopause (age at onset); LIHC cis rs9443189 0.526 rs6902898 chr6:76201856 G/A cg01950844 chr6:76311363 SENP6 0.88 10.66 0.5 4.25e-23 Prostate cancer; LIHC cis rs7027203 0.790 rs10123836 chr9:96584109 G/T cg13679303 chr9:96623674 NA -0.29 -6.61 -0.34 1.45e-10 DNA methylation (variation); LIHC cis rs311392 0.867 rs367108 chr8:55093142 G/A cg11783602 chr8:55087084 NA -0.31 -6.2 -0.32 1.66e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs2549003 1.000 rs17848418 chr5:131821188 C/T cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs739401 0.611 rs2239900 chr11:3030992 C/T cg25174290 chr11:3078921 CARS 0.53 8.16 0.4 6.33e-15 Longevity; LIHC cis rs3824867 0.879 rs10742806 chr11:47456226 T/A cg20307385 chr11:47447363 PSMC3 0.59 8.12 0.4 8.73e-15 Mean corpuscular hemoglobin; LIHC cis rs12928939 0.517 rs12149307 chr16:71968091 A/C cg03805757 chr16:71968109 PKD1L3 -0.93 -12.67 -0.57 2.02e-30 Post bronchodilator FEV1; LIHC cis rs7520050 0.966 rs10890354 chr1:46305347 G/A cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs6456156 0.586 rs13208636 chr6:167461965 T/G cg12798992 chr6:167411361 FGFR1OP 0.42 6.57 0.33 1.87e-10 Primary biliary cholangitis; LIHC cis rs3784262 0.904 rs12901462 chr15:58316487 A/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.34 -0.32 7.37e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs9649213 0.593 rs35535338 chr7:97962319 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.12e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs1062177 1.000 rs12518722 chr5:151231460 A/G cg00977110 chr5:151150581 G3BP1 0.51 6.34 0.32 7.1e-10 Preschool internalizing problems; LIHC cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC trans rs561341 1.000 rs550264 chr17:30317540 G/T cg20587970 chr11:113659929 NA -1.39 -11.8 -0.54 3.55e-27 Hip circumference adjusted for BMI; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg11494091 chr17:61959527 GH2 -0.45 -8.06 -0.4 1.29e-14 Prudent dietary pattern; LIHC cis rs1949733 0.917 rs10461079 chr4:8392724 G/A cg11789530 chr4:8429930 ACOX3 -0.82 -11.74 -0.54 5.64e-27 Response to antineoplastic agents; LIHC cis rs9549367 0.713 rs9549682 chr13:113830181 C/T cg00898013 chr13:113819073 PROZ -0.44 -7.39 -0.37 1.17e-12 Platelet distribution width; LIHC cis rs10838687 0.736 rs16938581 chr11:47271039 G/A cg26139080 chr11:47293733 MADD -0.42 -5.89 -0.3 9.47e-9 Proinsulin levels; LIHC cis rs3796352 1.000 rs71299622 chr3:52917038 G/A cg07884673 chr3:53033167 SFMBT1 0.92 6.37 0.33 5.99e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs6570726 0.791 rs7765675 chr6:145915077 A/C cg23711669 chr6:146136114 FBXO30 0.73 12.13 0.55 2.16e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs2239547 0.563 rs9839035 chr3:52909877 C/T cg11645453 chr3:52864694 ITIH4 0.32 8.09 0.4 1.04e-14 Schizophrenia; LIHC cis rs11048434 0.736 rs1476911 chr12:9090859 C/T cg04155231 chr12:9217510 LOC144571 0.32 6.2 0.32 1.62e-9 Sjögren's syndrome; LIHC cis rs11671005 0.693 rs11668757 chr19:58928299 A/T cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs2153535 0.580 rs7767926 chr6:8453557 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.68 0.42 1.65e-16 Motion sickness; LIHC cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.99 0.35 1.42e-11 Gut microbiome composition (summer); LIHC cis rs311392 0.966 rs454975 chr8:55087514 T/C cg11783602 chr8:55087084 NA -0.34 -6.57 -0.33 1.92e-10 Pelvic organ prolapse (moderate/severe); LIHC trans rs11088226 0.681 rs11700670 chr21:33938615 T/C cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.1e-34 Gastritis; LIHC cis rs317689 0.680 rs315140 chr12:69790780 A/T cg20891283 chr12:69753455 YEATS4 0.68 10.69 0.5 3.27e-23 Response to diuretic therapy; LIHC trans rs5756813 0.811 rs4396807 chr22:38138379 G/C cg19894588 chr14:64061835 NA -0.57 -8.11 -0.4 9.21e-15 Optic cup area;Vertical cup-disc ratio; LIHC cis rs11098499 0.954 rs3733519 chr4:120423448 A/G cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC cis rs10193935 0.901 rs9789740 chr2:42486799 A/G cg27598129 chr2:42591480 NA -0.7 -10.37 -0.49 4.24e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs2901460 0.509 rs11125898 chr2:62079895 T/C cg02183531 chr2:62113199 CCT4 -0.4 -5.89 -0.3 9.36e-9 Mean corpuscular volume; LIHC trans rs9834975 0.544 rs9811581 chr3:122280746 A/G cg18228109 chr6:162684441 PARK2 -0.32 -6.04 -0.31 4.04e-9 Diastolic blood pressure; LIHC cis rs12908161 1.000 rs35524990 chr15:85258203 T/C cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC cis rs2832191 0.716 rs7509628 chr21:30454252 C/T cg08807101 chr21:30365312 RNF160 0.78 11.84 0.54 2.36e-27 Dental caries; LIHC trans rs12478296 0.792 rs57482298 chr2:243011148 C/A cg01596870 chr19:55963115 NA -0.6 -7.15 -0.36 5.16e-12 Obesity-related traits; LIHC cis rs262150 0.659 rs2527236 chr7:158796644 C/T cg19418458 chr7:158789849 NA -0.4 -6.66 -0.34 1.1e-10 Facial morphology (factor 20); LIHC cis rs9902453 0.740 rs1382391 chr17:28111986 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs57244997 0.860 rs9458425 chr6:162376946 C/T cg17173639 chr6:162384350 PARK2 -0.56 -6.77 -0.34 5.74e-11 Mosquito bite size; LIHC cis rs6840360 0.571 rs62329101 chr4:152512239 G/T cg22705602 chr4:152727874 NA -0.32 -6.2 -0.32 1.6e-9 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.774 rs162344 chr21:44954522 G/A cg21573476 chr21:45109991 RRP1B -0.51 -9.33 -0.45 1.41e-18 Mean corpuscular volume; LIHC cis rs1865760 0.929 rs9467646 chr6:25957408 A/G cg03517284 chr6:25882590 NA -0.38 -5.8 -0.3 1.5e-8 Height; LIHC cis rs7267979 1.000 rs2258135 chr20:25272323 C/A cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs4700695 0.719 rs36923 chr5:65464783 G/C cg21114390 chr5:65439923 SFRS12 -0.59 -8.31 -0.41 2.27e-15 Facial morphology (factor 19); LIHC cis rs477895 0.713 rs67546972 chr11:63962162 G/A cg05555928 chr11:63887634 MACROD1 0.51 6.6 0.34 1.59e-10 Mean platelet volume; LIHC cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg24209194 chr3:40518798 ZNF619 0.44 6.35 0.32 6.74e-10 Renal cell carcinoma; LIHC cis rs694739 0.541 rs61886926 chr11:64133552 C/T cg23796481 chr11:64053134 BAD;GPR137 0.48 6.46 0.33 3.67e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs77633900 0.614 rs2585730 chr15:76989344 A/G cg21673338 chr15:77095150 SCAPER -0.5 -7.46 -0.37 6.99e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs17253792 0.822 rs2147114 chr14:56077118 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.6 -0.34 1.56e-10 Putamen volume; LIHC trans rs877282 0.898 rs12358966 chr10:758703 A/G cg22713356 chr15:30763199 NA 1.38 12.19 0.55 1.26e-28 Uric acid levels; LIHC cis rs10242455 0.571 rs28365067 chr7:99272310 G/A cg18809830 chr7:99032528 PTCD1 -0.86 -6.7 -0.34 8.38e-11 Blood metabolite levels; LIHC cis rs7799006 0.691 rs10447541 chr7:2301578 T/G cg02951883 chr7:2050386 MAD1L1 -0.4 -6.0 -0.31 4.97e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7582720 1.000 rs72934767 chr2:203766563 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4975709 0.569 rs2077269 chr5:1863506 C/T cg14773178 chr5:1868261 NA 0.27 7.2 0.36 3.94e-12 Cardiovascular disease risk factors; LIHC cis rs11718455 0.920 rs34909426 chr3:44000472 G/A cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs2228479 0.717 rs11649210 chr16:89807233 C/G cg00800038 chr16:89945340 TCF25 -0.57 -8.64 -0.42 2.12e-16 Skin colour saturation; LIHC cis rs9457247 0.515 rs2757039 chr6:167370353 G/T cg23791538 chr6:167370224 RNASET2 0.79 14.76 0.62 1.72e-38 Crohn's disease; LIHC cis rs6752107 0.967 rs3792111 chr2:234179690 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.14 0.4 7.27e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg00166722 chr3:10149974 C3orf24 0.48 5.74 0.3 2.14e-8 Alzheimer's disease; LIHC cis rs4888262 0.526 rs4887772 chr16:74537591 C/T cg01733217 chr16:74700730 RFWD3 0.77 15.04 0.63 1.35e-39 Testicular germ cell tumor; LIHC cis rs2842992 0.789 rs7765490 chr6:160204326 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.48 8.36 0.41 1.58e-15 Age-related macular degeneration (geographic atrophy); LIHC trans rs72960926 0.744 rs72950579 chr6:74915560 G/A cg07247405 chr1:2484626 LOC115110 0.54 6.32 0.32 8.29e-10 Metabolite levels (MHPG); LIHC cis rs2952156 1.000 rs2088126 chr17:37879030 A/G cg00129232 chr17:37814104 STARD3 -0.49 -8.76 -0.43 9.04e-17 Asthma; LIHC cis rs36051895 0.664 rs10117501 chr9:5094246 G/A cg02405213 chr9:5042618 JAK2 -0.69 -11.84 -0.54 2.54e-27 Pediatric autoimmune diseases; LIHC cis rs4689642 0.709 rs13133665 chr4:7226157 G/A cg21353189 chr4:7228343 SORCS2 0.37 6.24 0.32 1.29e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs10751667 0.643 rs11246348 chr11:939476 G/C cg06064525 chr11:970664 AP2A2 -0.54 -14.63 -0.62 5.45e-38 Alzheimer's disease (late onset); LIHC cis rs11122272 0.735 rs2024878 chr1:231528415 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.62 9.66 0.46 1.13e-19 Hemoglobin concentration; LIHC cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg15691649 chr6:25882328 NA 0.45 6.38 0.33 5.73e-10 Blood metabolite levels; LIHC cis rs11148252 0.574 rs73186430 chr13:53232891 T/C cg02158880 chr13:53174818 NA 0.38 5.97 0.31 5.99e-9 Lewy body disease; LIHC cis rs8072100 0.744 rs34537623 chr17:45530203 A/G cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.38 -6.04 -0.31 4.11e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs34779708 0.706 rs36027395 chr10:35550323 T/A cg03585969 chr10:35415529 CREM 0.74 10.67 0.5 3.8e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs17376456 0.877 rs2085960 chr5:93399934 A/G cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs1559088 1.000 rs7260051 chr19:33550111 C/A cg17764715 chr19:33622953 WDR88 0.41 5.83 0.3 1.28e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs3096299 0.933 rs3114848 chr16:89452771 G/A cg02187348 chr16:89574699 SPG7 0.51 7.6 0.38 2.8e-13 Multiple myeloma (IgH translocation); LIHC cis rs74233809 1.000 rs17115213 chr10:104681143 A/G cg03493300 chr10:104813866 CNNM2 0.47 6.07 0.31 3.31e-9 Birth weight; LIHC cis rs8062405 0.824 rs7191618 chr16:28565667 C/G cg07451762 chr16:28383216 NA 0.33 6.75 0.34 6.39e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7945705 0.870 rs10840142 chr11:8906078 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.41 7.04 0.36 1.09e-11 Hemoglobin concentration; LIHC cis rs533581 0.866 rs2968474 chr16:88970566 A/G cg03970086 chr16:88974840 CBFA2T3 -0.36 -7.27 -0.37 2.51e-12 Social autistic-like traits; LIHC cis rs1008375 1.000 rs6449319 chr4:17640283 T/A cg02297831 chr4:17616191 MED28 0.51 7.96 0.4 2.54e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1008375 0.966 rs2302393 chr4:17654341 G/A cg02297831 chr4:17616191 MED28 0.51 7.99 0.4 2.14e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs690037 0.641 rs538525 chr3:16376279 A/G cg23474789 chr3:16306055 DPH3;OXNAD1 0.58 8.65 0.42 2.09e-16 Optic nerve measurement (cup-to-disc ratio);Optic nerve measurement (cup area); LIHC cis rs929354 0.742 rs3808317 chr7:156944460 A/G cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC trans rs2073499 0.935 rs2526394 chr3:50189057 T/C cg21659725 chr3:3221576 CRBN -0.66 -7.27 -0.37 2.41e-12 Schizophrenia; LIHC cis rs7584330 0.504 rs11883500 chr2:238434434 C/T cg08992911 chr2:238395768 MLPH 0.49 5.98 0.31 5.74e-9 Prostate cancer; LIHC cis rs748404 0.660 rs2467738 chr15:43739936 T/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.41 0.37 1e-12 Lung cancer; LIHC cis rs7945718 0.967 rs12417886 chr11:12811731 A/C cg25843174 chr11:12811716 TEAD1 -0.38 -8.74 -0.43 1.06e-16 Educational attainment (years of education); LIHC cis rs11098499 0.818 rs55825515 chr4:120486402 A/G cg09307838 chr4:120376055 NA 0.74 11.16 0.52 7.13e-25 Corneal astigmatism; LIHC cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg17179660 chr6:151773299 C6orf211;RMND1 -0.43 -6.54 -0.33 2.24e-10 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19302970 chr18:9102753 NDUFV2 -0.4 -6.16 -0.32 2e-9 Pancreatic cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22068822 chr5:171682568 UBTD2 -0.45 -6.44 -0.33 4.13e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17074213 chr1:92351695 TGFBR3 0.51 6.58 0.34 1.76e-10 Lung function (FEV1/FVC); LIHC cis rs7301016 0.846 rs11174576 chr12:63026436 C/T cg11441379 chr12:63026424 NA 0.61 6.22 0.32 1.45e-9 IgG glycosylation; LIHC cis rs12971120 0.947 rs7241558 chr18:72169267 A/T cg26446133 chr18:72167187 CNDP2 -0.79 -15.9 -0.65 5.27e-43 Refractive error; LIHC cis rs986417 0.686 rs6573322 chr14:61117882 T/C cg27398547 chr14:60952738 C14orf39 0.64 6.16 0.32 2.07e-9 Gut microbiota (bacterial taxa); LIHC trans rs7829975 0.539 rs940031 chr8:8546848 C/T cg06710121 chr8:12235606 FAM66A 0.39 6.29 0.32 9.81e-10 Mood instability; LIHC cis rs6733011 0.508 rs4850889 chr2:99521385 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.87 -0.35 3.1e-11 Bipolar disorder; LIHC cis rs8062405 0.755 rs17640009 chr16:28595700 A/G cg16576597 chr16:28551801 NUPR1 0.46 7.11 0.36 6.81e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7584330 0.554 rs3751107 chr2:238427251 G/A cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs80282103 0.764 rs10047382 chr10:1102868 T/C cg08668510 chr10:1095578 IDI1 0.67 6.81 0.35 4.33e-11 Glomerular filtration rate (creatinine); LIHC cis rs7945071 0.507 rs4753891 chr11:110298547 A/G cg04157658 chr11:110243994 NA -0.34 -6.3 -0.32 9.37e-10 Cognitive function; LIHC cis rs2439831 1.000 rs689596 chr15:43761717 A/T cg15269541 chr15:43626905 ADAL -0.3 -5.76 -0.3 1.9e-8 Lung cancer in ever smokers; LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC trans rs61931739 0.500 rs7977186 chr12:34431486 C/G cg26384229 chr12:38710491 ALG10B 0.75 9.29 0.45 1.82e-18 Morning vs. evening chronotype; LIHC cis rs9896933 0.832 rs75552659 chr17:80804630 G/A cg20578329 chr17:80767326 TBCD -0.69 -6.73 -0.34 7.01e-11 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs12824058 0.831 rs11616174 chr12:130814503 A/G cg24229701 chr12:130821962 PIWIL1 0.44 6.77 0.34 5.55e-11 Menopause (age at onset); LIHC cis rs7312933 0.645 rs12049942 chr12:42587052 G/A cg17420585 chr12:42539391 GXYLT1 -0.37 -5.91 -0.3 8.32e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs3845702 0.736 rs115569960 chr2:180848214 C/T cg01881094 chr2:180872142 CWC22 1.13 9.88 0.47 2.1e-20 Schizophrenia; LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg07133347 chr1:107600762 PRMT6 -0.45 -6.85 -0.35 3.55e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9527 0.518 rs12776863 chr10:104641679 T/C cg15744005 chr10:104629667 AS3MT -0.41 -5.76 -0.3 1.88e-8 Arsenic metabolism; LIHC cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg05590025 chr7:65112418 INTS4L2 -0.66 -7.2 -0.36 3.94e-12 Diabetic kidney disease; LIHC cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg10295955 chr4:187884368 NA -0.97 -22.75 -0.78 1.95e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs2066819 1.000 rs79436528 chr12:56686997 C/T cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs909002 0.772 rs10914452 chr1:32074575 G/A cg13919466 chr1:32135498 COL16A1 -0.34 -6.33 -0.32 7.68e-10 Intelligence (multi-trait analysis); LIHC cis rs4934494 0.768 rs72818784 chr10:91549414 A/G cg19698084 chr10:91461284 KIF20B -0.47 -5.97 -0.31 5.82e-9 Red blood cell count; LIHC cis rs2274273 1.000 rs57970196 chr14:55600405 C/T cg01864836 chr14:55583639 NA -0.36 -6.15 -0.32 2.14e-9 Protein biomarker; LIHC cis rs2404602 0.647 rs11634266 chr15:77093461 A/G cg03037974 chr15:76606532 NA -0.61 -10.37 -0.49 4.4e-22 Blood metabolite levels; LIHC cis rs7412746 0.658 rs12097963 chr1:150870450 T/C cg17724175 chr1:150552817 MCL1 0.41 8.17 0.4 6.08e-15 Melanoma; LIHC cis rs17685 0.725 rs6947068 chr7:75662056 T/C cg04592579 chr7:75616294 TMEM120A -0.4 -6.92 -0.35 2.28e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6840360 0.571 rs62327278 chr4:152558790 G/C cg22705602 chr4:152727874 NA -0.32 -6.26 -0.32 1.16e-9 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.965 rs11887205 chr2:61774473 T/G cg15711740 chr2:61764176 XPO1 -0.44 -6.18 -0.32 1.87e-9 Tuberculosis; LIHC cis rs56104184 0.830 rs28556985 chr19:49351149 C/T cg15549821 chr19:49342101 PLEKHA4 -1.19 -10.09 -0.48 4.01e-21 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs9473924 0.505 rs9473931 chr6:50851411 C/G cg14470998 chr6:50812995 TFAP2B 0.89 10.6 0.5 6.74e-23 Body mass index; LIHC cis rs9549367 0.789 rs2287248 chr13:113889226 T/C cg00898013 chr13:113819073 PROZ -0.43 -7.49 -0.38 5.95e-13 Platelet distribution width; LIHC cis rs7193541 0.684 rs9923145 chr16:74686166 G/A cg01733217 chr16:74700730 RFWD3 0.92 22.66 0.77 4.62e-70 Multiple myeloma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.3.1245645R chr3:56681254 C3orf63 -0.29 -6.05 -0.31 3.91e-9 Cognitive function; LIHC cis rs6120849 0.754 rs36003887 chr20:33589107 G/A cg24642439 chr20:33292090 TP53INP2 0.66 7.22 0.36 3.49e-12 Protein C levels; LIHC cis rs11785400 0.793 rs3735993 chr8:143741170 G/A cg10596483 chr8:143751796 JRK 0.48 7.81 0.39 6.89e-14 Schizophrenia; LIHC cis rs56176327 0.583 rs7613603 chr3:49812866 C/T cg03060546 chr3:49711283 APEH -0.59 -6.86 -0.35 3.28e-11 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.954 rs11098526 chr4:120390359 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.69 0.46 9.12e-20 Corneal astigmatism; LIHC trans rs17685 0.712 rs6953342 chr7:75776753 T/C cg19862616 chr7:65841803 NCRNA00174 0.78 14.69 0.62 3.25e-38 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1008375 0.966 rs6813375 chr4:17649499 T/G cg15017067 chr4:17643749 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs894734 1.000 rs894734 chr12:54319727 A/G cg25024717 chr12:54324583 NA -0.28 -5.87 -0.3 1.03e-8 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs6445975 0.715 rs4681836 chr3:58267287 C/T cg23715586 chr3:58305044 RPP14 -0.37 -6.22 -0.32 1.45e-9 Systemic lupus erythematosus; LIHC cis rs7619427 0.544 rs9848662 chr3:43962778 T/C cg24966902 chr3:44043705 NA 0.46 7.08 0.36 7.99e-12 Schizophrenia; LIHC cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs941408 1.000 rs1736180 chr19:2796021 C/T cg06609049 chr19:2785107 THOP1 0.53 9.57 0.46 2.2e-19 Total cholesterol levels; LIHC cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg03517284 chr6:25882590 NA -0.48 -7.35 -0.37 1.46e-12 Height; LIHC cis rs7131987 0.650 rs7973786 chr12:29462744 C/T cg14222432 chr12:29376421 FAR2 0.34 6.62 0.34 1.35e-10 QT interval; LIHC cis rs4474465 0.915 rs10899504 chr11:78157983 C/A cg02023728 chr11:77925099 USP35 0.34 6.11 0.31 2.67e-9 Alzheimer's disease (survival time); LIHC cis rs919433 0.617 rs700638 chr2:198588950 A/C cg10820045 chr2:198174542 NA 0.5 7.59 0.38 3.04e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs738322 0.967 rs132971 chr22:38561911 T/G cg25457927 chr22:38595422 NA -0.27 -6.48 -0.33 3.16e-10 Cutaneous nevi; LIHC cis rs2236918 0.965 rs2488472 chr1:242019919 T/C cg17736920 chr1:242011382 EXO1 0.62 9.27 0.45 2.14e-18 Menopause (age at onset); LIHC cis rs7772486 0.686 rs4896827 chr6:145953338 T/A cg23711669 chr6:146136114 FBXO30 0.69 12.59 0.56 4.11e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs2732480 0.538 rs2732462 chr12:48696384 A/G cg21466736 chr12:48725269 NA -0.7 -10.49 -0.49 1.71e-22 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs1814175 0.502 rs12365889 chr11:49623034 G/A cg18944383 chr4:111397179 ENPEP 0.34 7.99 0.4 2.08e-14 Height; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg04282497 chr4:82350883 RASGEF1B 0.45 6.98 0.35 1.51e-11 Bilirubin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04219446 chr17:73629082 RECQL5;LOC643008 0.49 6.65 0.34 1.18e-10 Lung function (FEV1/FVC); LIHC cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg21724239 chr8:58056113 NA 0.62 7.9 0.39 3.77e-14 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.814 rs2839167 chr21:47661587 A/G cg13126279 chr21:47581558 C21orf56 -0.46 -7.38 -0.37 1.23e-12 Testicular germ cell tumor; LIHC cis rs611744 0.647 rs10106246 chr8:109268710 T/C cg18478394 chr8:109455254 TTC35 0.42 7.21 0.36 3.52e-12 Dupuytren's disease; LIHC cis rs753955 0.567 rs11617286 chr13:24409348 C/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.41 -7.14 -0.36 5.69e-12 Lung cancer; LIHC cis rs9303401 1.000 rs6503877 chr17:56841948 C/T cg05425664 chr17:57184151 TRIM37 -0.53 -7.51 -0.38 5.17e-13 Cognitive test performance; LIHC cis rs9457247 0.967 rs376097 chr6:167410878 A/G cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC cis rs74233809 1.000 rs12220743 chr10:104851912 C/T cg03493300 chr10:104813866 CNNM2 0.47 6.32 0.32 8.08e-10 Birth weight; LIHC cis rs5769765 0.773 rs9616382 chr22:50312979 C/T cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs7903847 0.667 rs10882931 chr10:99165794 C/A cg20016023 chr10:99160130 RRP12 -0.42 -6.79 -0.34 5.08e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs7312933 0.703 rs10459290 chr12:42613290 T/G cg01256987 chr12:42539512 GXYLT1 -0.43 -7.15 -0.36 5.19e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs9217 1.000 rs7209131 chr17:7376411 C/T cg08566640 chr11:64091735 NA 0.68 11.9 0.54 1.49e-27 Height; LIHC cis rs2153535 0.580 rs1832101 chr6:8460177 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs644799 0.525 rs3016206 chr11:95536724 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.69 0.57 1.64e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs921968 0.613 rs2710251 chr2:219543433 T/C cg02985541 chr2:219472218 PLCD4 -0.39 -6.51 -0.33 2.65e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2624839 0.630 rs2624841 chr3:50198415 C/T cg21467203 chr3:49911342 NA -0.42 -5.75 -0.3 2.03e-8 Intelligence (multi-trait analysis); LIHC cis rs6785206 0.772 rs6439134 chr3:128323504 C/T cg16766828 chr3:128327626 NA -0.62 -6.89 -0.35 2.77e-11 Lymphocyte percentage of white cells; LIHC cis rs6952808 0.531 rs3778998 chr7:2180753 C/A cg21782813 chr7:2030301 MAD1L1 0.37 6.34 0.32 7.38e-10 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs11673344 0.670 rs35011739 chr19:37434230 A/C cg27390819 chr19:37464633 NA -0.49 -5.84 -0.3 1.23e-8 Obesity-related traits; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg04234412 chr22:24373322 LOC391322 -0.7 -10.64 -0.5 4.95e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs74417235 0.684 rs13179754 chr5:154059845 C/T cg25588787 chr5:154027256 NA 0.38 5.9 0.3 8.9e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs614226 1.000 rs591992 chr12:121019323 T/C cg27489772 chr12:121021490 NA 0.53 5.87 0.3 1.04e-8 Type 1 diabetes nephropathy; LIHC cis rs4853036 0.951 rs10496175 chr2:70153848 A/G cg02498382 chr2:70120550 SNRNP27 -0.38 -6.14 -0.32 2.28e-9 Colorectal or endometrial cancer; LIHC cis rs17253792 0.731 rs28587929 chr14:56097492 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs2559856 1.000 rs2559857 chr12:102089399 A/C cg12924262 chr12:102091054 CHPT1 0.53 8.62 0.42 2.44e-16 Blood protein levels; LIHC cis rs4908768 0.906 rs12145445 chr1:8604370 C/G cg25722041 chr1:8623473 RERE 0.42 5.91 0.3 8.17e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3008870 0.755 rs2755271 chr1:67474977 C/T cg02640540 chr1:67518911 SLC35D1 0.41 6.39 0.33 5.41e-10 Lymphocyte percentage of white cells; LIHC cis rs7917772 0.503 rs7096072 chr10:104299976 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1577917 0.959 rs16876540 chr6:86612519 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.15 -0.36 5.28e-12 Response to antipsychotic treatment; LIHC cis rs9814567 1.000 rs6763093 chr3:134254995 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2463822 0.925 rs12292586 chr11:62156312 C/T cg06239285 chr11:62104954 ASRGL1 -0.97 -7.09 -0.36 7.81e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs11098499 0.738 rs28408407 chr4:120376030 C/G cg09307838 chr4:120376055 NA 0.79 12.54 0.56 5.98e-30 Corneal astigmatism; LIHC cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg06238570 chr21:40685208 BRWD1 0.58 6.86 0.35 3.34e-11 Cognitive function; LIHC cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg10360323 chr17:41437877 NA 0.41 6.07 0.31 3.33e-9 Menopause (age at onset); LIHC cis rs7095944 0.614 rs11245354 chr10:126450125 C/A cg08799069 chr10:126477246 METTL10 -0.38 -6.75 -0.34 6.32e-11 Asthma; LIHC cis rs739401 0.611 rs391188 chr11:3047634 G/A cg25174290 chr11:3078921 CARS 0.61 9.24 0.45 2.72e-18 Longevity; LIHC cis rs4908768 0.911 rs79769442 chr1:8658477 C/T cg20416874 chr1:8611966 RERE 0.53 6.77 0.34 5.75e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.75 0.57 1.04e-30 Prudent dietary pattern; LIHC cis rs3020736 0.500 rs2839708 chr22:42500745 A/G cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs7552404 1.000 rs7534754 chr1:76185308 G/A cg10523679 chr1:76189770 ACADM 0.64 8.83 0.43 5.54e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg16434002 chr17:42200994 HDAC5 -0.47 -7.14 -0.36 5.61e-12 Total body bone mineral density; LIHC cis rs11758351 0.660 rs113208674 chr6:26210465 C/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.26 0.37 2.59e-12 Gout;Renal underexcretion gout; LIHC cis rs7582180 0.663 rs2309794 chr2:100954270 G/A cg14675211 chr2:100938903 LONRF2 0.54 8.5 0.42 6.03e-16 Intelligence (multi-trait analysis); LIHC cis rs9434723 0.844 rs2239561 chr1:9304205 C/T cg04199779 chr1:9294473 H6PD -0.58 -6.67 -0.34 1.02e-10 Height; LIHC cis rs17539620 0.534 rs6557363 chr6:154827813 A/G cg20019720 chr6:154832845 CNKSR3 0.51 8.09 0.4 1.08e-14 Lipoprotein (a) levels; LIHC cis rs7089973 0.604 rs765174 chr10:116601888 C/T cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs11098499 0.754 rs28652763 chr4:120242312 C/T cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs614226 1.000 rs1167727 chr12:120965508 C/A cg27489772 chr12:121021490 NA 0.51 5.72 0.3 2.33e-8 Type 1 diabetes nephropathy; LIHC cis rs9303401 0.659 rs11079357 chr17:56902778 A/G cg25039879 chr17:56429692 SUPT4H1 0.76 8.73 0.43 1.17e-16 Cognitive test performance; LIHC cis rs3015497 0.789 rs923908 chr14:51123595 C/T cg09863266 chr14:51125203 SAV1 -0.42 -6.87 -0.35 3.11e-11 Mean platelet volume; LIHC cis rs7903847 0.642 rs1537646 chr10:99149922 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.38 -0.33 5.71e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11711311 0.955 rs9866806 chr3:113379865 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.39 6.34 0.32 7.21e-10 IgG glycosylation; LIHC cis rs921968 0.643 rs532475 chr2:219434208 C/T cg18887096 chr2:219472410 PLCD4 0.35 6.22 0.32 1.49e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs11676348 0.967 rs4672873 chr2:219005210 A/G cg00012203 chr2:219082015 ARPC2 -0.53 -7.25 -0.37 2.79e-12 Ulcerative colitis; LIHC trans rs2235573 0.551 rs139897 chr22:38399098 A/G cg19894588 chr14:64061835 NA 0.47 6.25 0.32 1.24e-9 Glioblastoma;Glioma; LIHC cis rs780094 0.585 rs3739095 chr2:27556721 C/T cg02592271 chr2:27665507 KRTCAP3 -0.41 -5.72 -0.3 2.28e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs2204008 0.580 rs11520047 chr12:38051778 T/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs11785400 1.000 rs3802232 chr8:143746701 A/G cg10596483 chr8:143751796 JRK 0.51 8.31 0.41 2.31e-15 Schizophrenia; LIHC cis rs1055129 0.681 rs7221792 chr17:73834690 T/G cg08125733 chr17:73851984 WBP2 0.51 8.23 0.41 4.1e-15 White matter hyperintensity burden; LIHC cis rs5769707 0.837 rs5770599 chr22:50019981 C/G cg07959070 chr22:50026188 C22orf34 -0.33 -8.37 -0.41 1.47e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs4803468 1.000 rs17318666 chr19:41940342 T/G cg14132834 chr19:41945861 ATP5SL 0.45 6.61 0.34 1.48e-10 Height; LIHC cis rs769267 0.930 rs1865034 chr19:19605763 C/T cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.34 0.32 7.45e-10 Tonsillectomy; LIHC cis rs3540 0.533 rs937793 chr15:91053583 A/G cg22089800 chr15:90895588 ZNF774 -0.52 -7.48 -0.37 6.53e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg20607798 chr8:58055168 NA 0.64 8.21 0.41 4.61e-15 Developmental language disorder (linguistic errors); LIHC cis rs6463523 0.898 rs66892628 chr7:759374 T/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.97 16.89 0.67 5.92e-47 Subjective well-being; LIHC cis rs2153535 0.580 rs2327056 chr6:8443305 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC trans rs73245065 0.558 rs68032173 chr10:30911030 C/A cg21500456 chr14:21190377 NA 0.45 6.23 0.32 1.37e-9 Bone mineral density (femoral neck); LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.24 -0.32 1.27e-9 Total body bone mineral density; LIHC cis rs9911578 0.967 rs7222789 chr17:56819853 C/G cg05425664 chr17:57184151 TRIM37 -0.57 -8.5 -0.42 5.75e-16 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg04504578 chr17:36831313 C17orf96 0.45 6.05 0.31 3.88e-9 Hepatitis; LIHC cis rs1499614 0.831 rs3800822 chr7:66147149 A/G cg18252515 chr7:66147081 NA 1.34 18.69 0.71 3.43e-54 Gout; LIHC cis rs12478296 0.685 rs6705935 chr2:242995110 C/T cg18898632 chr2:242989856 NA -0.51 -7.1 -0.36 7.24e-12 Obesity-related traits; LIHC cis rs7534824 0.543 rs61780295 chr1:101400264 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 6.9 0.35 2.61e-11 Refractive astigmatism; LIHC cis rs700651 0.789 rs6434949 chr2:198855510 T/A cg10820045 chr2:198174542 NA 0.46 6.99 0.35 1.42e-11 Intracranial aneurysm; LIHC cis rs6089584 0.888 rs2181590 chr20:60622843 T/C cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg11764359 chr7:65958608 NA 0.57 6.0 0.31 4.9e-9 Diabetic kidney disease; LIHC cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg12310025 chr6:25882481 NA -0.63 -7.84 -0.39 5.83e-14 Intelligence (multi-trait analysis); LIHC cis rs10463316 0.894 rs7710277 chr5:150767405 T/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.07e-10 Metabolite levels (Pyroglutamine); LIHC cis rs79976124 0.842 rs7760550 chr6:66628788 T/C cg07460842 chr6:66804631 NA 0.65 7.05 0.36 1.01e-11 Type 2 diabetes; LIHC trans rs2262909 0.962 rs73019844 chr19:22249925 T/C cg17074339 chr11:11642133 GALNTL4 0.4 6.09 0.31 3.09e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs10193935 0.605 rs10169492 chr2:42401961 G/T cg27598129 chr2:42591480 NA -0.76 -11.6 -0.53 1.87e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs950169 0.922 rs11635505 chr15:85097034 A/C cg17507749 chr15:85114479 UBE2QP1 -0.75 -9.04 -0.44 1.18e-17 Schizophrenia; LIHC cis rs7903847 0.642 rs9887991 chr10:99159634 T/C cg06359132 chr10:99160096 RRP12 -0.41 -6.39 -0.33 5.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs798766 1.000 rs798762 chr4:1731150 T/C cg21231739 chr4:1642635 FAM53A -0.37 -5.96 -0.31 6.22e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs11030122 0.604 rs10835557 chr11:4083121 A/G cg18678763 chr11:4115507 RRM1 -0.58 -8.55 -0.42 4.19e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs208520 0.507 rs9453585 chr6:66796668 C/T cg07460842 chr6:66804631 NA -1.0 -19.45 -0.72 2.83e-57 Exhaled nitric oxide output; LIHC cis rs700651 0.821 rs700666 chr2:198673544 G/A cg03934865 chr2:198174659 NA 0.46 6.58 0.34 1.74e-10 Intracranial aneurysm; LIHC cis rs8078723 0.966 rs57065891 chr17:38168227 C/T cg17467752 chr17:38218738 THRA 0.75 13.71 0.6 2.07e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs76419734 0.510 rs2553456 chr4:106751028 T/C cg24545054 chr4:106630052 GSTCD;INTS12 -0.71 -7.4 -0.37 1.09e-12 Post bronchodilator FEV1; LIHC cis rs9322817 0.715 rs6918700 chr6:105244526 A/T cg02098413 chr6:105308735 HACE1 -0.42 -7.71 -0.38 1.42e-13 Thyroid stimulating hormone; LIHC cis rs11758351 0.587 rs16891456 chr6:26234127 T/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs4919087 0.810 rs1468069 chr10:98988759 A/C cg25902810 chr10:99078978 FRAT1 0.64 9.17 0.44 4.39e-18 Monocyte count; LIHC cis rs1419980 0.730 rs11533525 chr12:7750251 G/A cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs7044106 0.648 rs2031369 chr9:123360294 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 10.84 0.51 1.02e-23 Hip circumference adjusted for BMI; LIHC cis rs7772486 0.632 rs9386128 chr6:146049053 G/A cg23711669 chr6:146136114 FBXO30 -0.63 -11.54 -0.53 3e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs12474201 0.894 rs4952842 chr2:46925730 C/A cg06386533 chr2:46925753 SOCS5 0.73 8.05 0.4 1.36e-14 Height; LIHC cis rs10876993 0.890 rs1092472 chr12:58036688 G/T cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.39 -0.33 5.51e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs2075371 1.000 rs1421485 chr7:133985181 C/T cg11752832 chr7:134001865 SLC35B4 0.52 7.83 0.39 6.14e-14 Mean platelet volume; LIHC cis rs875971 1.000 rs4718344 chr7:65874381 C/A cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs7106204 0.609 rs11821417 chr11:24279139 G/T ch.11.24196551F chr11:24239977 NA 0.66 5.94 0.31 6.93e-9 Response to Homoharringtonine (cytotoxicity); LIHC cis rs9611565 0.546 rs5758426 chr22:42098763 T/G cg06634786 chr22:41940651 POLR3H 0.57 6.21 0.32 1.57e-9 Vitiligo; LIHC cis rs801193 0.591 rs4506088 chr7:66135457 G/A cg18252515 chr7:66147081 NA 0.47 7.04 0.36 1.07e-11 Aortic root size; LIHC cis rs7572733 0.534 rs10211202 chr2:198771941 A/G cg03934865 chr2:198174659 NA 0.46 6.66 0.34 1.08e-10 Dermatomyositis; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg09429435 chr19:12914994 NA 0.41 6.31 0.32 8.56e-10 Bilirubin levels; LIHC cis rs2637266 1.000 rs2130798 chr10:78329563 C/T cg18941641 chr10:78392320 NA 0.29 6.19 0.32 1.72e-9 Pulmonary function; LIHC trans rs1624005 0.967 rs1667656 chr14:43392902 G/C cg11960719 chr5:1510684 LPCAT1 -0.37 -6.5 -0.33 2.81e-10 Methotrexate-induced interstitial lung disease in rheumatoid arthritis; LIHC cis rs4713118 0.629 rs203889 chr6:28021775 T/G cg16479474 chr6:28041457 NA 0.47 7.15 0.36 5.22e-12 Parkinson's disease; LIHC cis rs716804 0.703 rs11042687 chr11:10265036 G/A cg01453529 chr11:10209919 SBF2 -0.29 -5.86 -0.3 1.12e-8 Neuroticism; LIHC cis rs11792861 0.926 rs2271878 chr9:111868885 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.64e-16 Menarche (age at onset); LIHC cis rs3823572 0.542 rs11773892 chr7:133626334 G/T cg03336402 chr7:133662267 EXOC4 0.56 6.62 0.34 1.36e-10 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg06420487 chr17:61919686 SMARCD2 0.42 5.78 0.3 1.66e-8 Height; LIHC cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg20607798 chr8:58055168 NA 0.48 5.96 0.31 6.18e-9 Developmental language disorder (linguistic errors); LIHC cis rs6942756 0.806 rs7794622 chr7:128996268 T/C cg02491457 chr7:128862824 NA -0.56 -8.53 -0.42 4.8e-16 White matter hyperintensity burden; LIHC cis rs35110281 0.743 rs230640 chr21:44914815 A/T cg21573476 chr21:45109991 RRP1B 0.51 9.11 0.44 7.06e-18 Mean corpuscular volume; LIHC cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg07308232 chr7:1071921 C7orf50 -0.5 -8.32 -0.41 2.08e-15 Longevity;Endometriosis; LIHC cis rs7100689 0.577 rs9420359 chr10:82054873 C/T cg00277334 chr10:82204260 NA -0.55 -6.83 -0.35 3.86e-11 Post bronchodilator FEV1; LIHC cis rs4716602 0.550 rs12672151 chr7:156159053 A/G cg16983916 chr7:156159713 NA -0.32 -5.87 -0.3 1.02e-8 Anti-saccade response; LIHC cis rs2576037 0.526 rs11082562 chr18:44522671 T/C cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.98e-10 Personality dimensions; LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs11148252 0.553 rs9536236 chr13:53255012 T/A cg12458913 chr13:53173898 NA 0.51 8.33 0.41 1.92e-15 Lewy body disease; LIHC cis rs7296418 0.961 rs1790094 chr12:123586688 T/C cg05973401 chr12:123451056 ABCB9 0.5 7.83 0.39 5.99e-14 Platelet count; LIHC cis rs6582630 0.547 rs1589388 chr12:38416025 C/T cg26384229 chr12:38710491 ALG10B -0.47 -6.07 -0.31 3.35e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs6582630 0.638 rs12831496 chr12:38552604 G/A cg26384229 chr12:38710491 ALG10B -0.48 -6.72 -0.34 7.63e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs3806843 0.735 rs801189 chr5:140063091 A/G cg26395211 chr5:140044315 WDR55 0.4 5.88 0.3 9.85e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs3749237 0.595 rs10865955 chr3:49499829 G/A cg06212747 chr3:49208901 KLHDC8B 0.48 6.2 0.32 1.66e-9 Resting heart rate; LIHC cis rs1005277 0.579 rs2505194 chr10:38393881 C/T cg25427524 chr10:38739819 LOC399744 -0.64 -12.29 -0.55 5.32e-29 Extrinsic epigenetic age acceleration; LIHC cis rs12477438 0.765 rs13390672 chr2:99589829 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.24 -0.41 3.62e-15 Chronic sinus infection; LIHC cis rs17685 0.725 rs7807647 chr7:75628669 G/A cg16489192 chr7:75678113 MDH2;STYXL1 0.36 5.97 0.31 5.9e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7613875 0.620 rs3774734 chr3:50108792 C/A cg24110177 chr3:50126178 RBM5 0.56 9.12 0.44 6.64e-18 Body mass index; LIHC trans rs9641123 0.608 rs2528539 chr7:93248951 G/A cg09745688 chr16:2908918 PRSS22 -0.36 -6.34 -0.32 7.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg13629201 chr9:5111420 JAK2 0.41 6.32 0.32 8.08e-10 Alopecia areata; LIHC cis rs9814567 1.000 rs9809619 chr3:134280948 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11098499 0.866 rs72676074 chr4:120359841 A/C cg09307838 chr4:120376055 NA 0.79 12.54 0.56 6.18e-30 Corneal astigmatism; LIHC cis rs2857078 0.654 rs4793083 chr17:42312973 C/T cg19774624 chr17:42201019 HDAC5 0.54 7.63 0.38 2.33e-13 Red cell distribution width;Reticulocyte count; LIHC cis rs17401966 0.838 rs4846206 chr1:10310258 G/C cg15208524 chr1:10270712 KIF1B 0.37 5.76 0.3 1.86e-8 Hepatocellular carcinoma; LIHC cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg06466757 chr4:1255808 NA 0.34 5.79 0.3 1.61e-8 Obesity-related traits; LIHC cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.11e-8 Bipolar disorder; LIHC cis rs11190604 1.000 rs3750630 chr10:102275780 A/G cg07080220 chr10:102295463 HIF1AN 0.55 8.15 0.4 7e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7927771 0.864 rs2053979 chr11:47439444 A/G cg20307385 chr11:47447363 PSMC3 -0.48 -6.23 -0.32 1.4e-9 Subjective well-being; LIHC cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg19454999 chr17:41278357 BRCA1;NBR2 -0.38 -5.76 -0.3 1.9e-8 Menopause (age at onset); LIHC cis rs2404602 0.598 rs71405204 chr15:76635305 C/G cg03037974 chr15:76606532 NA -0.66 -10.84 -0.51 9.89e-24 Blood metabolite levels; LIHC cis rs9640161 0.750 rs11769348 chr7:150026753 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 0.55 9.15 0.44 5.33e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs2976388 0.609 rs2572907 chr8:143801938 G/A cg06565975 chr8:143823917 SLURP1 0.33 6.14 0.32 2.24e-9 Urinary tract infection frequency; LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.85 0.39 5.46e-14 Height; LIHC trans rs1728785 1.000 rs1170445 chr16:68573064 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.82e-9 Ulcerative colitis; LIHC cis rs6061231 0.834 rs2427311 chr20:60970123 A/G cg24112000 chr20:60950667 NA -0.6 -8.97 -0.44 2.05e-17 Colorectal cancer; LIHC cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg23978390 chr7:1156363 C7orf50 0.55 8.35 0.41 1.73e-15 Longevity;Endometriosis; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg23788167 chr9:74979561 ZFAND5 0.5 6.52 0.33 2.47e-10 Lung function (FEV1); LIHC cis rs2806561 0.765 rs9426692 chr1:23508426 C/T cg19743168 chr1:23544995 NA 0.34 5.72 0.3 2.33e-8 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04903962 chr12:53615479 RARG 0.53 7.27 0.37 2.41e-12 Lung function (FEV1/FVC); LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg10299061 chr3:53078990 SFMBT1 -0.59 -6.45 -0.33 3.89e-10 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs35883536 0.935 rs1577510 chr1:101114295 G/A cg14515779 chr1:101123966 NA 0.63 12.13 0.55 2.12e-28 Monocyte count; LIHC cis rs7572733 0.534 rs6434943 chr2:198762192 T/G cg00792783 chr2:198669748 PLCL1 0.48 6.98 0.35 1.57e-11 Dermatomyositis; LIHC cis rs2153535 0.580 rs9379216 chr6:8481235 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs6960043 1.000 rs6960043 chr7:15052860 C/T cg19272540 chr7:15055459 NA 0.21 5.84 0.3 1.22e-8 Type 2 diabetes; LIHC cis rs6499188 0.571 rs1645975 chr16:68564448 C/T cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs9372253 1.000 rs9384740 chr6:110716207 G/A cg00083206 chr6:110721305 DDO -0.32 -6.49 -0.33 3.02e-10 Platelet distribution width; LIHC cis rs1144333 0.510 rs1146652 chr1:76273708 A/G cg03433033 chr1:76189801 ACADM -0.52 -7.49 -0.38 5.75e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg21724239 chr8:58056113 NA 0.49 6.52 0.33 2.55e-10 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg15691649 chr6:25882328 NA 0.47 6.58 0.34 1.75e-10 Blood metabolite levels; LIHC cis rs8180040 0.701 rs34103310 chr3:47073266 C/T cg27129171 chr3:47204927 SETD2 0.66 11.61 0.53 1.75e-26 Colorectal cancer; LIHC cis rs8017423 0.791 rs7146250 chr14:90711703 A/G cg14092571 chr14:90743983 NA -0.39 -6.11 -0.31 2.68e-9 Mortality in heart failure; LIHC cis rs6450176 0.564 rs31228 chr5:53325994 C/G ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.45 -0.59 2.1e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs10638925 1 rs10638925 chr3:194119749 C/CCATAAA cg00834899 chr3:194121120 GP5 0.36 5.93 0.31 7.45e-9 Platelet distribution width; LIHC cis rs7223966 1.000 rs8075061 chr17:61804723 A/G cg05941027 chr17:61774174 LIMD2 0.36 7.54 0.38 4.22e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg27535305 chr1:53392650 SCP2 0.32 6.28 0.32 9.99e-10 Monocyte count; LIHC cis rs11098699 0.821 rs11731898 chr4:124220979 C/A cg09941581 chr4:124220074 SPATA5 0.33 6.64 0.34 1.23e-10 Mosquito bite size; LIHC cis rs11190604 1.000 rs2495741 chr10:102331795 A/G cg07080220 chr10:102295463 HIF1AN 0.55 7.81 0.39 6.85e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg01518246 chr11:63870912 FLRT1;MACROD1 0.45 6.19 0.32 1.7e-9 Mean platelet volume; LIHC cis rs7107174 1.000 rs1385601 chr11:77936064 A/C cg02023728 chr11:77925099 USP35 0.44 8.62 0.42 2.58e-16 Testicular germ cell tumor; LIHC cis rs9733 0.744 rs12126004 chr1:150889877 T/C cg17724175 chr1:150552817 MCL1 -0.34 -6.37 -0.33 6.1e-10 Tonsillectomy; LIHC cis rs12079745 0.793 rs12074492 chr1:169215363 C/G cg09363564 chr1:169337483 NME7;BLZF1 -0.75 -6.98 -0.35 1.53e-11 QT interval; LIHC cis rs7613875 0.543 rs34034116 chr3:49959156 C/A cg05623727 chr3:50126028 RBM5 0.34 5.82 0.3 1.39e-8 Body mass index; LIHC cis rs8072100 0.840 rs12452796 chr17:45479733 G/T cg19378624 chr17:45501242 LOC100272146;C17orf57 0.37 5.87 0.3 1.03e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1728785 0.901 rs1631910 chr16:68603335 G/A cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2.07e-9 Ulcerative colitis; LIHC cis rs116095464 0.558 rs55664502 chr5:270485 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs9790314 1.000 rs459697 chr3:161093420 G/A cg03342759 chr3:160939853 NMD3 -0.71 -8.58 -0.42 3.42e-16 Morning vs. evening chronotype; LIHC trans rs2832077 0.943 rs2272701 chr21:30190907 C/T cg14791747 chr16:20752902 THUMPD1 0.47 6.29 0.32 9.64e-10 Cognitive test performance; LIHC cis rs6089829 0.816 rs6062397 chr20:61668268 A/G cg08564027 chr20:61660810 NA 0.4 7.59 0.38 3.01e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 5.98 0.31 5.48e-9 Schizophrenia; LIHC cis rs1982963 0.627 rs8020559 chr14:52490690 T/G cg10843707 chr14:52510701 NID2 0.37 6.2 0.32 1.67e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6665290 0.904 rs12409428 chr1:227189969 T/C cg10327440 chr1:227177885 CDC42BPA -1.18 -25.74 -0.81 4.9e-82 Myeloid white cell count; LIHC cis rs1475911 0.708 rs56185023 chr21:43521538 T/C cg24372256 chr21:43528868 UMODL1;C21orf128 -0.35 -5.82 -0.3 1.39e-8 IgG glycosylation; LIHC cis rs644799 1.000 rs527899 chr11:95529242 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7940866 0.903 rs7940465 chr11:130861339 C/T cg12179176 chr11:130786555 SNX19 0.51 7.32 0.37 1.8e-12 Schizophrenia; LIHC trans rs875971 0.767 rs1695815 chr7:65831344 A/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs7131987 0.834 rs7139273 chr12:29434650 T/C cg14222432 chr12:29376421 FAR2 0.34 6.69 0.34 9.16e-11 QT interval; LIHC cis rs798554 0.591 rs757791 chr7:2867296 A/G cg13628971 chr7:2884303 GNA12 0.41 6.51 0.33 2.67e-10 Height; LIHC cis rs6952808 0.823 rs10950448 chr7:1966492 G/C cg04267008 chr7:1944627 MAD1L1 -0.67 -10.69 -0.5 3.22e-23 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.654 rs6766230 chr3:47196209 C/A cg27129171 chr3:47204927 SETD2 0.58 9.54 0.46 2.83e-19 Colorectal cancer; LIHC cis rs17685 0.725 rs4476928 chr7:75642107 C/A cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.17 0.32 1.95e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1432089 0.773 rs62344302 chr4:171785314 C/T cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs16854884 0.632 rs1466941 chr3:143670131 A/G cg06585982 chr3:143692056 C3orf58 0.64 9.06 0.44 1.05e-17 Economic and political preferences (feminism/equality); LIHC cis rs9649213 0.555 rs34695842 chr7:97931062 G/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.85 -0.3 1.17e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs6598955 0.543 rs60676610 chr1:26543421 G/C cg04990556 chr1:26633338 UBXN11 0.76 11.03 0.51 2.02e-24 Obesity-related traits; LIHC cis rs2404602 0.716 rs8039545 chr15:76707247 A/G cg03037974 chr15:76606532 NA 0.8 16.57 0.67 1.05e-45 Blood metabolite levels; LIHC cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC trans rs116095464 0.558 rs6878061 chr5:223072 A/G cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg24503407 chr1:205819492 PM20D1 0.87 12.39 0.56 2.17e-29 Menarche (age at onset); LIHC cis rs6120849 0.615 rs11167248 chr20:33538721 G/T cg06115741 chr20:33292138 TP53INP2 0.49 5.92 0.3 7.78e-9 Protein C levels; LIHC cis rs28830936 0.510 rs2412640 chr15:42124082 C/T cg17847044 chr15:42102381 MAPKBP1 0.47 10.8 0.5 1.37e-23 Diastolic blood pressure; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg05208895 chr7:100276062 GNB2 0.42 6.25 0.32 1.23e-9 Bilirubin levels; LIHC cis rs400736 0.562 rs7551900 chr1:8178526 A/C cg25007680 chr1:8021821 PARK7 -0.55 -8.3 -0.41 2.41e-15 Response to antidepressants and depression; LIHC cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg15691649 chr6:25882328 NA -0.61 -8.18 -0.4 5.76e-15 Intelligence (multi-trait analysis); LIHC cis rs477692 0.967 rs488143 chr10:131407369 A/C cg05714579 chr10:131428358 MGMT 0.48 8.19 0.41 5.09e-15 Response to temozolomide; LIHC cis rs6429082 0.783 rs390539 chr1:235679690 A/C cg26050004 chr1:235667680 B3GALNT2 0.47 7.36 0.37 1.34e-12 Adiposity; LIHC trans rs11148252 0.595 rs9526968 chr13:53240183 T/C cg18335740 chr13:41363409 SLC25A15 0.56 10.31 0.49 7e-22 Lewy body disease; LIHC cis rs9902453 1.000 rs9896062 chr17:28357047 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs2797160 0.714 rs1777220 chr6:126022602 G/T cg05901451 chr6:126070800 HEY2 0.49 7.87 0.39 4.6e-14 Endometrial cancer; LIHC cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg13047869 chr3:10149882 C3orf24 0.5 5.94 0.31 7e-9 Alzheimer's disease; LIHC cis rs4934494 0.768 rs768805 chr10:91455205 C/A cg19698084 chr10:91461284 KIF20B -0.49 -6.51 -0.33 2.69e-10 Red blood cell count; LIHC cis rs477692 1.000 rs569235 chr10:131411620 T/C cg19680672 chr10:131412579 MGMT -0.45 -7.02 -0.35 1.22e-11 Response to temozolomide; LIHC cis rs7312933 0.703 rs10880268 chr12:42599122 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 7.66 0.38 1.95e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6933660 0.760 rs1825368 chr6:151775259 C/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.57 -8.65 -0.42 2e-16 Menarche (age at onset); LIHC trans rs3960554 0.529 rs7800970 chr7:75880198 C/T cg19862616 chr7:65841803 NCRNA00174 -0.61 -9.54 -0.46 2.8e-19 Eotaxin levels; LIHC cis rs963731 0.649 rs2060989 chr2:39293530 G/A cg04010122 chr2:39346883 SOS1 -0.61 -6.06 -0.31 3.69e-9 Corticobasal degeneration; LIHC cis rs6912958 0.712 rs9444526 chr6:88326402 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.99 -0.4 2.03e-14 Monocyte percentage of white cells; LIHC cis rs4665809 1.000 rs7599132 chr2:26279810 A/T cg04944784 chr2:26401820 FAM59B 0.67 8.44 0.42 9.11e-16 Gut microbiome composition (summer); LIHC cis rs10791097 0.667 rs4937584 chr11:130741761 A/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg05552183 chr6:42928497 GNMT 0.68 10.09 0.48 3.89e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9916302 0.904 rs3964723 chr17:37403979 C/T cg07936489 chr17:37558343 FBXL20 -0.79 -12.53 -0.56 6.65e-30 Glomerular filtration rate (creatinine); LIHC cis rs992157 0.798 rs10932772 chr2:219177148 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.78 12.4 0.56 2.1e-29 Colorectal cancer; LIHC cis rs3782089 1.000 rs3782089 chr11:65336819 C/T cg08676812 chr11:65308423 LTBP3 0.92 6.44 0.33 4.05e-10 Height; LIHC cis rs1494950 1.000 rs2643083 chr4:14995589 G/T cg12377275 chr4:15005593 CPEB2 -0.79 -6.68 -0.34 9.6e-11 Political ideology; LIHC cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg16405210 chr4:1374714 KIAA1530 -0.92 -14.65 -0.62 4.62e-38 Longevity; LIHC cis rs8180040 0.932 rs1038394 chr3:47464122 A/G cg16586182 chr3:47516702 SCAP -0.58 -11.33 -0.52 1.75e-25 Colorectal cancer; LIHC cis rs7131987 0.903 rs11050163 chr12:29420398 C/T cg12903224 chr12:29470962 FAR2 -0.37 -5.93 -0.31 7.47e-9 QT interval; LIHC trans rs7395662 0.591 rs12807777 chr11:48593754 A/T cg03929089 chr4:120376271 NA -0.41 -6.1 -0.31 2.91e-9 HDL cholesterol; LIHC cis rs881375 0.967 rs2416806 chr9:123690292 G/C cg14580859 chr9:123691850 NA 0.39 6.85 0.35 3.45e-11 Rheumatoid arthritis; LIHC cis rs2645694 0.626 rs2703115 chr4:77824442 C/T cg03477792 chr4:77819574 ANKRD56 0.57 8.35 0.41 1.73e-15 Emphysema distribution in smoking; LIHC cis rs903552 0.932 rs11858490 chr15:102007443 G/T cg25677261 chr15:102009856 PCSK6 0.44 6.02 0.31 4.41e-9 Diabetic kidney disease; LIHC cis rs7223966 1.000 rs7209758 chr17:61913621 C/T cg05941027 chr17:61774174 LIMD2 0.35 7.37 0.37 1.32e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7923837 0.651 rs3824735 chr10:94354204 T/G cg25506282 chr10:94462361 NA 0.34 5.84 0.3 1.23e-8 Body mass index;Multiple sclerosis; LIHC cis rs3008870 1.000 rs912797 chr1:67413478 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs1712517 0.771 rs61869827 chr10:105079439 T/C cg05636881 chr10:105038444 INA 0.48 7.58 0.38 3.19e-13 Migraine; LIHC cis rs8084351 0.599 rs12605603 chr18:50679866 C/G cg24270629 chr18:50823537 DCC -0.45 -6.78 -0.34 5.39e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg13409248 chr3:40428643 ENTPD3 0.5 8.3 0.41 2.42e-15 Renal cell carcinoma; LIHC trans rs1347297 0.774 rs9973732 chr2:179281435 A/G cg14011486 chr1:26737247 LIN28 0.45 7.14 0.36 5.5e-12 Alzheimer disease and age of onset; LIHC trans rs10242455 0.557 rs59672032 chr7:99058697 T/C cg09045935 chr12:6379348 NA 0.8 6.58 0.34 1.8e-10 Blood metabolite levels; LIHC cis rs7587476 0.531 rs35933323 chr2:215674090 T/G cg04004882 chr2:215674386 BARD1 -0.58 -8.33 -0.41 2.02e-15 Neuroblastoma; LIHC cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg06634786 chr22:41940651 POLR3H -0.82 -8.94 -0.44 2.48e-17 Vitiligo; LIHC trans rs2727020 0.612 rs9787891 chr11:49413494 G/A cg03929089 chr4:120376271 NA -0.7 -11.01 -0.51 2.49e-24 Coronary artery disease; LIHC trans rs4718428 0.705 rs4717331 chr7:66378886 C/T cg10756647 chr7:56101905 PSPH 0.63 8.66 0.42 1.86e-16 Corneal structure; LIHC cis rs7124681 0.565 rs2904127 chr11:47817290 A/G cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs10256972 0.869 rs1007766 chr7:1034903 G/A cg04025307 chr7:1156635 C7orf50 0.48 7.7 0.38 1.48e-13 Longevity;Endometriosis; LIHC cis rs116095464 0.558 rs10059907 chr5:205360 G/C cg22857025 chr5:266934 NA -1.65 -16.58 -0.67 9.67e-46 Breast cancer; LIHC cis rs34779708 0.966 rs10827487 chr10:35406878 T/A cg03585969 chr10:35415529 CREM 0.87 13.18 0.58 2.31e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9303401 0.659 rs34275691 chr17:56736640 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs9354352 0.935 rs9354354 chr6:66699333 A/G cg07460842 chr6:66804631 NA -0.56 -8.87 -0.43 4.18e-17 Initial pursuit acceleration in psychotic disorders; LIHC cis rs4665809 1.000 rs12469163 chr2:26283587 T/C cg04944784 chr2:26401820 FAM59B -0.66 -8.22 -0.41 4.16e-15 Gut microbiome composition (summer); LIHC cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs10751667 0.643 rs7396767 chr11:938808 G/A ch.11.42038R chr11:967971 AP2A2 0.53 9.72 0.47 7.06e-20 Alzheimer's disease (late onset); LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg15382696 chr6:118971807 C6orf204 -0.59 -6.6 -0.34 1.53e-10 Diastolic blood pressure; LIHC cis rs3740540 0.530 rs2362507 chr10:126290820 A/G cg04949429 chr10:126290192 LHPP 0.45 7.34 0.37 1.55e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs9399135 0.967 rs9321481 chr6:135352648 C/G cg22676075 chr6:135203613 NA -0.39 -6.25 -0.32 1.21e-9 Red blood cell count; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs2153535 0.580 rs1119690 chr6:8460660 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs507080 0.961 rs673770 chr11:118550601 T/G cg04173919 chr11:118528438 PHLDB1 0.31 5.72 0.3 2.38e-8 Serum metabolite levels; LIHC cis rs11663156 1.000 rs10515960 chr18:50913822 C/A cg24270629 chr18:50823537 DCC -0.46 -6.1 -0.31 2.89e-9 Intelligence (multi-trait analysis); LIHC cis rs7116495 0.609 rs10450664 chr11:71636655 A/G cg26138937 chr11:71823887 C11orf51 -1.24 -9.79 -0.47 4.05e-20 Severe influenza A (H1N1) infection; LIHC cis rs9918079 0.580 rs13120905 chr4:15612288 A/T cg21329975 chr4:15471214 CC2D2A 0.41 6.23 0.32 1.38e-9 Obesity-related traits; LIHC cis rs8062405 0.690 rs6498089 chr16:28629300 C/T cg07382826 chr16:28625726 SULT1A1 -0.43 -6.27 -0.32 1.06e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg08280861 chr8:58055591 NA 0.49 6.13 0.31 2.38e-9 Developmental language disorder (linguistic errors); LIHC cis rs7212938 0.509 rs3893044 chr17:38103016 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.39 6.24 0.32 1.3e-9 Asthma and hay fever; LIHC trans rs7504990 0.802 rs56383134 chr18:50388655 G/A cg08535148 chr4:26321143 RBPJ 0.52 6.14 0.32 2.26e-9 Gallbladder cancer; LIHC cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs7552404 0.889 rs380075 chr1:76106961 T/A cg22875332 chr1:76189707 ACADM -0.49 -7.3 -0.37 2.08e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4407350 1.000 rs4823331 chr22:44923082 T/C cg11695653 chr22:44894386 LDOC1L -0.37 -6.03 -0.31 4.3e-9 Intelligence (multi-trait analysis); LIHC cis rs16854884 0.538 rs61359084 chr3:143738362 T/C cg06585982 chr3:143692056 C3orf58 0.54 6.96 0.35 1.77e-11 Economic and political preferences (feminism/equality); LIHC trans rs941408 1.000 rs941406 chr19:2803623 A/G cg19676328 chr12:49525230 TUBA1B -0.38 -6.2 -0.32 1.65e-9 Total cholesterol levels; LIHC cis rs11229555 0.574 rs12272310 chr11:58186462 A/C cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6466055 0.666 rs12671047 chr7:104999535 C/A cg04380332 chr7:105027541 SRPK2 -0.37 -6.95 -0.35 1.88e-11 Schizophrenia; LIHC cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg11062466 chr8:58055876 NA 0.4 5.79 0.3 1.62e-8 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg10757852 chr3:141319363 RASA2 0.48 6.6 0.34 1.56e-10 Hepatitis; LIHC cis rs7572733 0.534 rs734037 chr2:198749269 G/A cg10820045 chr2:198174542 NA 0.47 6.97 0.35 1.6e-11 Dermatomyositis; LIHC cis rs6565180 0.926 rs4787643 chr16:30393660 G/A cg17640201 chr16:30407289 ZNF48 0.78 12.91 0.57 2.53e-31 Tonsillectomy; LIHC cis rs10791097 0.694 rs7926167 chr11:130745045 T/C cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6424115 1.000 rs6424115 chr1:24153231 A/G cg15997130 chr1:24165203 NA -0.45 -9.22 -0.45 3.03e-18 Immature fraction of reticulocytes; LIHC cis rs12249377 0.519 rs4520504 chr10:92602373 T/C cg14313238 chr10:92632228 RPP30 0.39 6.48 0.33 3.28e-10 White matter microstructure (global fractional anisotropy); LIHC cis rs9733 0.596 rs2867304 chr1:150630995 G/A cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs17376456 0.877 rs34184666 chr5:93444584 T/C cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs11628318 0.853 rs7140280 chr14:103026991 C/T cg12046867 chr14:103022105 NA -0.53 -7.82 -0.39 6.55e-14 Platelet count; LIHC cis rs56011263 0.687 rs11734460 chr4:705074 C/T cg14024328 chr4:719362 PCGF3 -0.47 -7.08 -0.36 8.46e-12 White blood cell count; LIHC cis rs734999 0.505 rs10797439 chr1:2540364 G/A cg18854424 chr1:2615690 NA 0.33 7.42 0.37 9.44e-13 Ulcerative colitis; LIHC cis rs7927592 0.913 rs67005337 chr11:68307758 A/C cg01657329 chr11:68192670 LRP5 -0.47 -6.07 -0.31 3.46e-9 Total body bone mineral density; LIHC trans rs11039798 1.000 rs115429994 chr11:48761183 C/G cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs1443512 0.812 rs1975472 chr12:54337083 A/G cg17410650 chr12:54324560 NA -0.37 -6.73 -0.34 7.12e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg20887711 chr4:1340912 KIAA1530 0.82 13.03 0.58 8.39e-32 Longevity; LIHC cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg18357526 chr6:26021779 HIST1H4A 0.52 6.49 0.33 3.04e-10 Blood metabolite levels; LIHC cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs12500138 1.000 rs59353629 chr4:166218077 T/A cg25064052 chr4:166216151 KLHL2 -0.61 -5.77 -0.3 1.8e-8 Cognitive function; LIHC cis rs1018836 0.923 rs10808615 chr8:91569704 A/T cg16814680 chr8:91681699 NA -0.61 -9.75 -0.47 5.44e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs11711311 0.955 rs34048496 chr3:113414121 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.45 8.3 0.41 2.37e-15 IgG glycosylation; LIHC cis rs1385374 0.698 rs2170988 chr12:129290876 A/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.7 0.38 1.46e-13 Systemic lupus erythematosus; LIHC cis rs7772486 0.875 rs9373483 chr6:146364194 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.21e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7312774 0.618 rs9651926 chr12:107356820 G/A cg16260113 chr12:107380972 MTERFD3 0.94 12.16 0.55 1.66e-28 Severe influenza A (H1N1) infection; LIHC cis rs11031096 0.678 rs61899666 chr11:4178711 C/A cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.46e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs787274 1.000 rs787271 chr9:115549463 C/T cg13803584 chr9:115635662 SNX30 -0.56 -6.21 -0.32 1.51e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7192750 0.586 rs7204708 chr16:71986946 C/T cg06353428 chr16:71660113 MARVELD3 -0.77 -8.3 -0.41 2.43e-15 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs2463822 0.925 rs2513075 chr11:62102408 C/T cg06239285 chr11:62104954 ASRGL1 0.92 6.89 0.35 2.76e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs4891159 0.790 rs35516239 chr18:74129942 C/T cg24786174 chr18:74118243 ZNF516 -0.77 -14.11 -0.61 6.13e-36 Longevity; LIHC cis rs35306767 0.855 rs55697724 chr10:885622 T/C cg20503657 chr10:835505 NA 1.35 14.76 0.62 1.75e-38 Eosinophil percentage of granulocytes; LIHC cis rs66573146 0.572 rs66734745 chr4:6948765 T/C cg15105060 chr4:7024189 TBC1D14 -0.68 -6.1 -0.31 2.88e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14850771 chr21:34775459 IFNGR2 -0.51 -6.14 -0.32 2.28e-9 Systolic blood pressure; LIHC cis rs10504073 0.584 rs56074306 chr8:49940282 C/T cg00325661 chr8:49890786 NA 0.36 7.98 0.4 2.27e-14 Blood metabolite ratios; LIHC cis rs6952808 0.965 rs11768541 chr7:1894884 G/A cg10360139 chr7:1886902 MAD1L1 -0.39 -5.86 -0.3 1.11e-8 Bipolar disorder and schizophrenia; LIHC cis rs2075671 0.903 rs11983334 chr7:100302434 C/T cg16850897 chr7:100343110 ZAN -0.4 -5.83 -0.3 1.26e-8 Other erythrocyte phenotypes; LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20261243 chr20:44718728 NCOA5 0.44 6.54 0.33 2.27e-10 Pancreatic cancer; LIHC cis rs35883536 1.000 rs871151 chr1:101123737 G/A cg14515779 chr1:101123966 NA -0.69 -13.86 -0.6 5.63e-35 Monocyte count; LIHC cis rs950169 0.763 rs35372971 chr15:84941795 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 8.67 0.42 1.78e-16 Schizophrenia; LIHC cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg18357526 chr6:26021779 HIST1H4A -0.53 -6.5 -0.33 2.81e-10 Blood metabolite levels; LIHC cis rs7208859 0.623 rs3752021 chr17:29111043 G/C cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7412746 0.611 rs11803940 chr1:150685835 A/G cg15448220 chr1:150897856 SETDB1 0.43 6.77 0.34 5.77e-11 Melanoma; LIHC trans rs1814175 0.676 rs1721999 chr11:49917372 A/G cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs7534824 0.543 rs6693339 chr1:101424431 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.61 -7.37 -0.37 1.32e-12 Refractive astigmatism; LIHC cis rs2073300 0.609 rs56334525 chr20:23365812 A/G cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2727020 0.576 rs1917321 chr11:49377760 A/C cg03929089 chr4:120376271 NA -0.49 -7.45 -0.37 7.54e-13 Coronary artery disease; LIHC cis rs12142240 0.698 rs6695043 chr1:46844530 A/G cg00530320 chr1:46809349 NSUN4 -0.53 -5.92 -0.3 7.85e-9 Menopause (age at onset); LIHC cis rs712039 0.617 rs36081240 chr17:35785054 G/A cg16670864 chr17:35848621 DUSP14 0.35 5.86 0.3 1.09e-8 Tuberculosis; LIHC cis rs763121 0.853 rs4821811 chr22:39075145 C/T cg06022373 chr22:39101656 GTPBP1 0.65 11.28 0.52 2.57e-25 Menopause (age at onset); LIHC cis rs9296092 0.538 rs34222093 chr6:33519584 G/C cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg06873352 chr17:61820015 STRADA 0.71 12.65 0.56 2.48e-30 Prudent dietary pattern; LIHC cis rs3789045 0.866 rs61817482 chr1:204570347 G/A cg17419461 chr1:204415978 PIK3C2B -0.41 -6.11 -0.31 2.71e-9 Educational attainment (college completion); LIHC trans rs60843830 1.000 rs57542652 chr2:228088 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.65 9.18 0.44 4.16e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs1707322 1.000 rs12403666 chr1:46431621 G/A cg06784218 chr1:46089804 CCDC17 0.37 6.61 0.34 1.51e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg13770153 chr20:60521292 NA -0.62 -13.62 -0.59 4.95e-34 Obesity-related traits; LIHC trans rs10411161 1.000 rs10402988 chr19:52363104 G/A cg22319618 chr22:45562946 NUP50 -0.51 -6.83 -0.35 4.01e-11 Breast cancer; LIHC cis rs11711311 0.747 rs2895415 chr3:113345565 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -6.92 -0.35 2.26e-11 IgG glycosylation; LIHC cis rs67478160 0.571 rs1155751 chr14:104286547 C/G cg01849466 chr14:104193079 ZFYVE21 -0.44 -6.94 -0.35 1.95e-11 Schizophrenia; LIHC cis rs10028773 0.506 rs12374346 chr4:120281705 G/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Educational attainment; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg00280220 chr17:61926910 NA 0.41 6.78 0.34 5.24e-11 Prudent dietary pattern; LIHC cis rs9296092 0.538 rs62405953 chr6:33524760 C/T cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.7e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs2732480 0.577 rs2634691 chr12:48708259 G/T cg21466736 chr12:48725269 NA -0.72 -10.68 -0.5 3.68e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 10.54 0.5 1.13e-22 Platelet count; LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg26338869 chr17:61819248 STRADA 0.62 8.75 0.43 9.87e-17 Prudent dietary pattern; LIHC cis rs12928939 0.815 rs61753635 chr16:71660404 G/A cg03805757 chr16:71968109 PKD1L3 -0.56 -6.31 -0.32 8.46e-10 Post bronchodilator FEV1; LIHC cis rs801193 1.000 rs7783924 chr7:66209057 A/C cg11764359 chr7:65958608 NA 0.71 10.58 0.5 8.11e-23 Aortic root size; LIHC cis rs7772486 0.754 rs9386134 chr6:146145508 G/A cg23711669 chr6:146136114 FBXO30 0.75 13.56 0.59 8.27e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs2439831 0.850 rs7168158 chr15:44050376 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.5 0.42 6.09e-16 Lung cancer in ever smokers; LIHC cis rs4845570 0.850 rs11204892 chr1:151768048 A/G cg07092448 chr1:151763213 TDRKH 0.94 17.02 0.68 1.71e-47 Coronary artery disease; LIHC cis rs4803468 1.000 rs878083 chr19:41897688 G/A cg09537434 chr19:41945824 ATP5SL -0.99 -20.33 -0.74 8.13e-61 Height; LIHC cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.94 18.94 0.72 3.34e-55 Height; LIHC cis rs7582720 1.000 rs72934738 chr2:203740861 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4891159 0.548 rs660342 chr18:74130896 C/G cg24786174 chr18:74118243 ZNF516 0.83 17.32 0.68 1.06e-48 Longevity; LIHC cis rs911119 1.000 rs3088162 chr20:23607752 C/A cg16589663 chr20:23618590 CST3 0.76 7.97 0.4 2.37e-14 Chronic kidney disease; LIHC cis rs7100689 0.646 rs10788586 chr10:82117435 A/G cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs9325144 0.671 rs12818797 chr12:39019409 A/G cg26384229 chr12:38710491 ALG10B -0.44 -6.27 -0.32 1.09e-9 Morning vs. evening chronotype; LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg08469215 chr1:156261351 TMEM79 0.4 6.59 0.34 1.68e-10 Tonsillectomy; LIHC cis rs1801251 1.000 rs2012221 chr2:233566848 T/C cg08000102 chr2:233561755 GIGYF2 0.75 11.25 0.52 3.35e-25 Coronary artery disease; LIHC cis rs9522267 0.535 rs914037 chr13:112235308 A/G cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs10751667 0.600 rs14346 chr11:1011829 T/C ch.11.42038R chr11:967971 AP2A2 0.59 10.83 0.51 1.03e-23 Alzheimer's disease (late onset); LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg02990361 chr1:107599529 PRMT6 0.59 9.58 0.46 2e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7772486 0.875 rs11155452 chr6:146424631 C/T cg23711669 chr6:146136114 FBXO30 0.64 10.83 0.51 1.07e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.790 rs2254257 chr6:146203724 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.2 0.32 1.61e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs6489882 0.807 rs1859334 chr12:113367332 C/T cg10175203 chr3:128143634 NA 0.38 6.12 0.31 2.6e-9 Chronic lymphocytic leukemia; LIHC cis rs12478296 0.685 rs6705935 chr2:242995110 C/T cg06360820 chr2:242988706 NA -0.84 -12.75 -0.57 9.57e-31 Obesity-related traits; LIHC cis rs10791097 0.694 rs7942621 chr11:130751308 C/G cg14779329 chr11:130786720 SNX19 0.42 6.38 0.33 5.83e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1348850 0.574 rs12988366 chr2:178417945 A/C cg27490568 chr2:178487706 NA -1.01 -11.52 -0.53 3.46e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs507080 0.961 rs1784298 chr11:118548665 T/C cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC cis rs11098499 0.820 rs6829903 chr4:120506884 C/T cg09307838 chr4:120376055 NA 0.75 11.81 0.54 3.06e-27 Corneal astigmatism; LIHC cis rs57590327 0.508 rs4622918 chr3:81965382 A/G cg07356753 chr3:81810745 GBE1 -0.53 -8.36 -0.41 1.57e-15 Extraversion; LIHC cis rs72781680 0.898 rs10490751 chr2:24001356 A/G cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs9534288 0.912 rs3736944 chr13:46619316 T/C cg15192986 chr13:46630673 CPB2 -0.58 -8.61 -0.42 2.66e-16 Blood protein levels; LIHC cis rs12540874 0.542 rs3807562 chr7:50566671 G/A cg14593290 chr7:50529359 DDC -0.36 -6.23 -0.32 1.35e-9 Systemic sclerosis; LIHC cis rs9325144 0.581 rs6582564 chr12:38671282 G/A cg26384229 chr12:38710491 ALG10B -0.49 -7.49 -0.38 5.75e-13 Morning vs. evening chronotype; LIHC cis rs7107174 1.000 rs7119933 chr11:78049750 A/C cg02023728 chr11:77925099 USP35 0.42 8.05 0.4 1.4e-14 Testicular germ cell tumor; LIHC cis rs3617 0.572 rs2256332 chr3:52855865 A/G cg11645453 chr3:52864694 ITIH4 -0.21 -5.86 -0.3 1.07e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg12463550 chr7:65579703 CRCP -0.67 -6.86 -0.35 3.29e-11 Diabetic kidney disease; LIHC cis rs4730250 0.655 rs75243311 chr7:106890791 C/T cg02696742 chr7:106810147 HBP1 -0.5 -5.86 -0.3 1.07e-8 Osteoarthritis; LIHC cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg08219700 chr8:58056026 NA 0.52 6.08 0.31 3.27e-9 Developmental language disorder (linguistic errors); LIHC cis rs2075371 0.932 rs2241333 chr7:133970750 C/T cg20476274 chr7:133979776 SLC35B4 0.76 12.99 0.57 1.23e-31 Mean platelet volume; LIHC cis rs2245008 0.762 rs168800 chr16:83980391 T/C cg27171569 chr16:83987465 OSGIN1 0.43 6.18 0.32 1.82e-9 Pursuit maintenance gain; LIHC cis rs35306767 0.903 rs11253494 chr10:937047 C/T cg26597838 chr10:835615 NA 1.11 13.68 0.59 2.68e-34 Eosinophil percentage of granulocytes; LIHC cis rs10791097 0.694 rs11222369 chr11:130744670 A/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2404602 0.709 rs11072597 chr15:76763514 C/A cg23625390 chr15:77176239 SCAPER -0.48 -8.03 -0.4 1.61e-14 Blood metabolite levels; LIHC cis rs9486719 0.843 rs3860229 chr6:97036559 T/C cg06623918 chr6:96969491 KIAA0776 -0.69 -7.95 -0.4 2.69e-14 Migraine;Coronary artery disease; LIHC cis rs2839186 0.967 rs17176131 chr21:47705237 T/C cg12379764 chr21:47803548 PCNT -0.6 -8.79 -0.43 7.28e-17 Testicular germ cell tumor; LIHC cis rs9910055 0.530 rs2269907 chr17:42294215 G/A cg10896456 chr17:42255109 ASB16;C17orf65 0.42 7.32 0.37 1.8e-12 Total body bone mineral density; LIHC cis rs240764 0.817 rs239239 chr6:101094554 A/G cg09795085 chr6:101329169 ASCC3 0.53 7.48 0.37 6.49e-13 Neuroticism; LIHC cis rs6835098 1.000 rs28477433 chr4:174085820 T/C cg27433088 chr4:174089019 GALNT7 0.39 7.18 0.36 4.26e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs7552404 1.000 rs4949876 chr1:76173377 C/T cg10523679 chr1:76189770 ACADM 0.66 9.17 0.44 4.39e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8063761 1.000 rs8063761 chr16:90027626 A/T cg05185784 chr16:90016020 DEF8 0.39 6.38 0.33 5.79e-10 Squamous cell carcinoma; LIHC cis rs1816752 1.000 rs7999554 chr13:25009769 C/A cg02811702 chr13:24901961 NA 0.25 6.14 0.32 2.26e-9 Obesity-related traits; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg03181376 chr2:43454447 ZFP36L2;LOC100129726 -0.46 -6.24 -0.32 1.27e-9 Lung cancer in ever smokers; LIHC cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg16145915 chr7:1198662 ZFAND2A -0.39 -9.76 -0.47 5.32e-20 Longevity;Endometriosis; LIHC cis rs4919694 0.572 rs72846714 chr10:104878454 G/A cg04362960 chr10:104952993 NT5C2 0.81 7.12 0.36 6.54e-12 Arsenic metabolism; LIHC cis rs1538970 1.000 rs61791368 chr1:45867944 T/C cg05343316 chr1:45956843 TESK2 0.57 8.23 0.41 4.12e-15 Platelet count; LIHC cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg18357526 chr6:26021779 HIST1H4A 0.91 13.3 0.58 8.36e-33 Intelligence (multi-trait analysis); LIHC cis rs311392 0.584 rs388075 chr8:55099893 T/C cg11783602 chr8:55087084 NA -0.31 -6.16 -0.32 2.02e-9 Pelvic organ prolapse (moderate/severe); LIHC trans rs10411161 0.702 rs11879336 chr19:52389627 C/T cg22319618 chr22:45562946 NUP50 -0.64 -8.58 -0.42 3.4e-16 Breast cancer; LIHC cis rs523522 0.962 rs10849754 chr12:120940418 A/C cg27279351 chr12:120934652 DYNLL1 0.67 12.05 0.55 3.99e-28 High light scatter reticulocyte count; LIHC cis rs1664789 0.935 rs1694064 chr5:53279690 C/T ch.5.1024479R chr5:53302184 ARL15 0.53 8.24 0.41 3.79e-15 Waist circumference adjusted for body mass index; LIHC cis rs919433 0.617 rs700645 chr2:198605514 A/G cg00792783 chr2:198669748 PLCL1 0.44 6.41 0.33 4.85e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs11098499 0.615 rs28551750 chr4:120264901 C/T cg25214090 chr10:38739885 LOC399744 0.45 7.33 0.37 1.64e-12 Corneal astigmatism; LIHC cis rs12893668 0.703 rs2403197 chr14:104053764 C/T cg19000871 chr14:103996768 TRMT61A -0.4 -6.47 -0.33 3.37e-10 Reticulocyte count; LIHC cis rs2274273 1.000 rs11621351 chr14:55616740 C/A cg01864836 chr14:55583639 NA -0.36 -6.14 -0.32 2.3e-9 Protein biomarker; LIHC trans rs6489882 0.671 rs7135577 chr12:113358106 A/G cg10175203 chr3:128143634 NA 0.39 6.4 0.33 5.08e-10 Chronic lymphocytic leukemia; LIHC cis rs3796352 1.000 rs13072395 chr3:52980573 T/C cg04865290 chr3:52927548 TMEM110 -0.51 -5.81 -0.3 1.4e-8 Immune reponse to smallpox (secreted IL-2); LIHC cis rs651907 0.535 rs35799195 chr3:101521927 A/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs7223966 1.000 rs11654335 chr17:61797579 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.96 0.35 1.72e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6545883 0.965 rs6545872 chr2:61724568 G/A cg15711740 chr2:61764176 XPO1 -0.42 -5.9 -0.3 8.53e-9 Tuberculosis; LIHC cis rs12915845 0.545 rs4407042 chr15:89077885 T/A cg05013243 chr15:89149849 MIR1179 -0.38 -6.79 -0.34 4.95e-11 Menarche (age at onset); LIHC trans rs11098499 0.909 rs10017335 chr4:120381523 C/G cg25214090 chr10:38739885 LOC399744 -0.59 -9.25 -0.45 2.53e-18 Corneal astigmatism; LIHC cis rs7772486 0.597 rs6570732 chr6:146245151 G/A cg23711669 chr6:146136114 FBXO30 -0.64 -9.35 -0.45 1.14e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.47 -10.82 -0.51 1.15e-23 Calcium levels; LIHC trans rs1814175 0.781 rs11040681 chr11:49981654 G/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.05 -0.78 1.27e-71 Height; LIHC cis rs66573146 0.831 rs67315413 chr4:6987910 T/C cg00086871 chr4:6988644 TBC1D14 0.79 5.86 0.3 1.08e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs672413 0.620 rs663646 chr5:78285778 G/A cg04677158 chr5:78279841 ARSB 0.37 6.24 0.32 1.32e-9 Blood and toenail selenium levels;Blood protein levels; LIHC cis rs507080 0.769 rs2077173 chr11:118492591 G/A cg04173919 chr11:118528438 PHLDB1 0.32 5.85 0.3 1.16e-8 Serum metabolite levels; LIHC cis rs12464559 0.826 rs78355157 chr2:152632574 C/T cg01189475 chr2:152685088 ARL5A -0.71 -6.65 -0.34 1.2e-10 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs2072499 0.931 rs1052053 chr1:156202173 A/G cg25208724 chr1:156163844 SLC25A44 0.62 10.96 0.51 3.57e-24 Testicular germ cell tumor; LIHC cis rs1949733 1.000 rs6447875 chr4:8503206 T/C cg11789530 chr4:8429930 ACOX3 0.78 11.86 0.54 2.06e-27 Response to antineoplastic agents; LIHC cis rs7937682 0.824 rs539524 chr11:111477325 A/G cg09085632 chr11:111637200 PPP2R1B -0.92 -11.2 -0.52 5.26e-25 Primary sclerosing cholangitis; LIHC cis rs2797685 0.898 rs697693 chr1:7886424 C/T cg04725166 chr1:7887271 PER3 -0.44 -7.82 -0.39 6.81e-14 Crohn's disease; LIHC cis rs4908760 0.539 rs10864367 chr1:8847380 C/T cg20416874 chr1:8611966 RERE -0.55 -9.85 -0.47 2.53e-20 Vitiligo; LIHC cis rs903552 0.932 rs11858490 chr15:102007443 G/T cg06707286 chr15:102010195 PCSK6 0.47 6.77 0.34 5.48e-11 Diabetic kidney disease; LIHC trans rs10838798 0.504 rs11039634 chr11:48297843 A/G cg15704280 chr7:45808275 SEPT13 -0.42 -6.37 -0.33 6.26e-10 Height; LIHC cis rs7312933 0.607 rs7965392 chr12:42540280 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 7.91 0.39 3.69e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs748404 0.676 rs4401024 chr15:43650335 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.99 0.48 9e-21 Lung cancer; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg07343612 chr16:622815 PIGQ -0.83 -15.17 -0.63 4.12e-40 Height; LIHC cis rs7927771 0.542 rs3886262 chr11:47817010 T/G cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC cis rs1403694 0.966 rs1656910 chr3:186438993 A/C cg12454167 chr3:186435060 KNG1 0.29 7.05 0.36 1e-11 Blood protein levels; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs12188164 0.840 rs67665078 chr5:428754 G/A cg19980199 chr5:480033 SLC9A3 0.34 5.76 0.3 1.91e-8 Cystic fibrosis severity; LIHC trans rs1005277 0.579 rs2474587 chr10:38420666 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.15 -0.52 8.04e-25 Extrinsic epigenetic age acceleration; LIHC cis rs4728302 0.869 rs7792546 chr7:133595502 G/T cg10665199 chr7:133106180 EXOC4 0.37 6.53 0.33 2.4e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.86e-9 Total body bone mineral density; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.73 10.65 0.5 4.5e-23 Lymphocyte counts; LIHC cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg18867708 chr6:26865862 GUSBL1 -0.5 -7.69 -0.38 1.59e-13 Schizophrenia; LIHC cis rs1799949 0.965 rs6503726 chr17:41284742 T/C cg05368731 chr17:41323189 NBR1 0.63 10.32 0.49 6.43e-22 Menopause (age at onset); LIHC cis rs7212590 0.748 rs8074176 chr17:57861995 G/A cg10252138 chr17:58120427 NA -0.58 -5.89 -0.3 9.48e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs1580019 0.885 rs4460270 chr7:32496450 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs7208859 0.524 rs28760584 chr17:29141017 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7927592 0.913 rs3740629 chr11:68343593 C/T cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.94e-14 Total body bone mineral density; LIHC cis rs2204008 0.604 rs2320521 chr12:38253789 A/G cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.57e-21 Bladder cancer; LIHC cis rs7412746 0.634 rs72704658 chr1:150833010 T/C cg18016565 chr1:150552671 MCL1 0.56 10.28 0.49 9.21e-22 Melanoma; LIHC trans rs1814175 0.935 rs7925863 chr11:49615802 C/A cg15704280 chr7:45808275 SEPT13 -1.0 -21.24 -0.75 1.89e-64 Height; LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 11.99 0.54 6.88e-28 Height; LIHC cis rs7772486 0.805 rs4896831 chr6:145959481 T/C cg23711669 chr6:146136114 FBXO30 0.59 10.77 0.5 1.69e-23 Lobe attachment (rater-scored or self-reported); LIHC trans rs7618501 1.000 rs4855867 chr3:49745822 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg22029157 chr1:209979665 IRF6 -0.47 -7.56 -0.38 3.83e-13 Monobrow; LIHC cis rs4423214 0.819 rs7938885 chr11:71170043 T/C cg05163923 chr11:71159392 DHCR7 0.87 13.22 0.58 1.58e-32 Vitamin D levels; LIHC cis rs9818758 0.607 rs35108630 chr3:49088356 T/A cg00383909 chr3:49044727 WDR6 0.85 7.04 0.36 1.09e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs57502260 0.790 rs7129320 chr11:68388220 G/A cg20283391 chr11:68216788 NA -0.48 -5.93 -0.31 7.56e-9 Total body bone mineral density (age 45-60); LIHC trans rs11098499 0.954 rs10017371 chr4:120293776 A/G cg25214090 chr10:38739885 LOC399744 0.57 8.89 0.43 3.63e-17 Corneal astigmatism; LIHC cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.44 -8.01 -0.4 1.79e-14 Prudent dietary pattern; LIHC cis rs826838 0.838 rs11183646 chr12:38799846 A/T cg13010199 chr12:38710504 ALG10B 0.65 7.82 0.39 6.73e-14 Heart rate; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00436174 chr2:128051630 ERCC3 0.41 6.34 0.32 7.11e-10 Calcium levels; LIHC cis rs6687430 0.526 rs6688558 chr1:10611403 A/G cg17425144 chr1:10567563 PEX14 0.48 8.77 0.43 8.45e-17 Hand grip strength; LIHC cis rs472402 0.580 rs10060745 chr5:6658003 T/C cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.46 -5.75 -0.3 2.03e-8 Response to amphetamines; LIHC cis rs2439831 1.000 rs2467739 chr15:43740196 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.78 13.44 0.59 2.41e-33 Lung cancer in ever smokers; LIHC cis rs12893668 0.703 rs4906338 chr14:104050357 A/G cg24130564 chr14:104152367 KLC1 -0.54 -8.68 -0.42 1.66e-16 Reticulocyte count; LIHC cis rs36051895 0.530 rs6476951 chr9:5221614 A/G cg02405213 chr9:5042618 JAK2 -0.63 -10.05 -0.48 5.48e-21 Pediatric autoimmune diseases; LIHC cis rs6840360 0.762 rs62327352 chr4:152670780 C/A cg22705602 chr4:152727874 NA -0.33 -6.85 -0.35 3.49e-11 Intelligence (multi-trait analysis); LIHC cis rs3820068 0.581 rs72645881 chr1:15928203 C/T cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs694739 0.654 rs10897488 chr11:64140806 T/C cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.08e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs5769765 0.908 rs138891 chr22:50227741 G/A cg02269571 chr22:50332266 NA -0.61 -8.37 -0.41 1.46e-15 Schizophrenia; LIHC cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg13607699 chr17:42295918 UBTF 0.44 7.13 0.36 5.9e-12 Total body bone mineral density; LIHC cis rs6733011 0.508 rs13004700 chr2:99527568 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.44 -6.32 -0.32 8.12e-10 Bipolar disorder; LIHC cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.85 -0.39 5.42e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs7843479 0.582 rs7009693 chr8:21775314 C/T cg17168535 chr8:21777572 XPO7 0.61 11.07 0.51 1.47e-24 Mean corpuscular volume; LIHC cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg24209194 chr3:40518798 ZNF619 0.42 5.95 0.31 6.66e-9 Renal cell carcinoma; LIHC cis rs4076764 1.000 rs7528020 chr1:163426537 G/A cg24596788 chr1:163392923 NA -0.22 -6.95 -0.35 1.88e-11 Motion sickness; LIHC cis rs858239 0.600 rs10256359 chr7:23123877 C/T cg23682824 chr7:23144976 KLHL7 0.42 6.27 0.32 1.12e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9911578 0.967 rs4132925 chr17:56938016 C/G cg12560992 chr17:57184187 TRIM37 -0.98 -17.78 -0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs7727544 0.684 rs272849 chr5:131690241 A/G cg24060327 chr5:131705240 SLC22A5 -0.57 -8.42 -0.41 1.09e-15 Blood metabolite levels; LIHC cis rs35146811 1.000 rs35146811 chr7:99720994 A/C cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.42 6.09 0.31 3.1e-9 Coronary artery disease; LIHC cis rs11792861 0.926 rs77567374 chr9:111835034 T/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.79 -0.34 5e-11 Menarche (age at onset); LIHC cis rs8062405 0.824 rs7191618 chr16:28565667 C/G cg00204512 chr16:28754710 NA 0.34 6.95 0.35 1.86e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7520050 0.966 rs4076006 chr1:46438076 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.43 6.35 0.32 6.93e-10 Red blood cell count;Reticulocyte count; LIHC cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg22907277 chr7:1156413 C7orf50 0.43 6.12 0.31 2.55e-9 Longevity;Endometriosis; LIHC cis rs611744 1.000 rs611744 chr8:109228008 A/G cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg05590025 chr7:65112418 INTS4L2 0.59 6.51 0.33 2.69e-10 Diabetic kidney disease; LIHC cis rs36051895 0.502 rs12347799 chr9:5215954 G/A cg02405213 chr9:5042618 JAK2 -0.59 -9.4 -0.45 7.97e-19 Pediatric autoimmune diseases; LIHC cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg16405210 chr4:1374714 KIAA1530 -0.94 -16.06 -0.66 1.24e-43 Longevity; LIHC cis rs6088580 0.634 rs7271970 chr20:32987666 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg02990361 chr1:107599529 PRMT6 -0.6 -9.85 -0.47 2.54e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7534824 0.625 rs61780327 chr1:101449810 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.38 0.37 1.22e-12 Refractive astigmatism; LIHC cis rs7582720 1.000 rs6738618 chr2:203749439 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg05368731 chr17:41323189 NBR1 0.74 12.67 0.57 2.06e-30 Menopause (age at onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg09047884 chr22:43484984 TTLL1 -0.39 -6.1 -0.31 2.85e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg24693881 chr1:107596107 NA 0.54 9.41 0.45 7.51e-19 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg26526709 chr7:35077807 DPY19L1 0.47 6.9 0.35 2.55e-11 Morning vs. evening chronotype; LIHC cis rs10254118 0.757 rs7788086 chr7:133135206 C/T cg10665199 chr7:133106180 EXOC4 0.52 8.29 0.41 2.55e-15 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg27228074 chr10:104678015 CNNM2 0.49 6.11 0.31 2.67e-9 Hepatitis; LIHC cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg16405210 chr4:1374714 KIAA1530 0.43 6.37 0.33 6.02e-10 Obesity-related traits; LIHC cis rs4975709 0.589 rs1466606 chr5:1865055 C/T cg15595755 chr5:1867978 NA 0.41 8.42 0.41 1.08e-15 Cardiovascular disease risk factors; LIHC cis rs240764 0.817 rs151573 chr6:101086333 T/C cg09795085 chr6:101329169 ASCC3 0.51 7.15 0.36 5.22e-12 Neuroticism; LIHC cis rs2303759 1.000 rs2303759 chr19:49869051 T/G cg22307029 chr19:49891270 CCDC155 0.57 9.3 0.45 1.75e-18 Multiple sclerosis; LIHC cis rs1046896 0.553 rs8073413 chr17:80836005 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.41 6.25 0.32 1.2e-9 Glycated hemoglobin levels; LIHC cis rs611744 0.967 rs686584 chr8:109192357 G/A cg21045802 chr8:109455806 TTC35 0.51 8.68 0.42 1.63e-16 Dupuytren's disease; LIHC cis rs3793683 1.000 rs3793683 chr10:134568387 G/T cg27286337 chr10:134555280 INPP5A -1.05 -19.89 -0.73 5.05e-59 Migraine; LIHC cis rs2617583 0.967 rs2550947 chr5:1450506 T/C cg07151155 chr5:1473589 LPCAT1 -0.41 -6.39 -0.33 5.35e-10 Breast cancer; LIHC cis rs6748734 1.000 rs4311055 chr2:241821017 T/C cg20140201 chr2:241835670 C2orf54 -0.46 -6.16 -0.32 2.09e-9 Urinary metabolites; LIHC cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg27572855 chr1:25598939 RHD 0.38 7.87 0.39 4.79e-14 Erythrocyte sedimentation rate; LIHC cis rs17445774 1.000 rs17445774 chr2:200859249 A/G cg17644776 chr2:200775616 C2orf69 -0.49 -5.86 -0.3 1.08e-8 LDL cholesterol to HDL cholesterol ratio; LIHC cis rs1707322 0.928 rs10732844 chr1:46372688 T/C cg06784218 chr1:46089804 CCDC17 0.34 5.96 0.31 6.34e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11792861 0.890 rs3087979 chr9:111781779 T/C cg05043794 chr9:111880884 C9orf5 -0.3 -7.04 -0.36 1.08e-11 Menarche (age at onset); LIHC cis rs9916302 0.904 rs8065879 chr17:37515978 G/A cg00129232 chr17:37814104 STARD3 0.38 6.08 0.31 3.27e-9 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg20607798 chr8:58055168 NA 0.67 8.28 0.41 2.86e-15 Developmental language disorder (linguistic errors); LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg15586393 chr4:1244086 CTBP1;C4orf42 -0.42 -5.97 -0.31 5.8e-9 Longevity; LIHC cis rs1707322 0.686 rs2991987 chr1:46081422 C/G cg06784218 chr1:46089804 CCDC17 -0.42 -7.76 -0.39 9.95e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9303401 0.625 rs34963822 chr17:56988424 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.52 0.59 1.15e-33 Cognitive test performance; LIHC cis rs1712517 0.873 rs7903004 chr10:105004101 G/A cg05636881 chr10:105038444 INA -0.39 -6.14 -0.32 2.27e-9 Migraine; LIHC cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg26119090 chr2:26468346 HADHA;HADHB -1.06 -14.51 -0.62 1.58e-37 Gut microbiome composition (summer); LIHC cis rs1127311 0.875 rs9427102 chr1:154586957 A/G cg17218026 chr1:154582156 ADAR 0.36 7.09 0.36 7.66e-12 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs896854 0.517 rs10112447 chr8:95955701 C/T cg09323728 chr8:95962352 TP53INP1 -0.29 -5.78 -0.3 1.64e-8 Type 2 diabetes; LIHC trans rs9747201 1.000 rs36048409 chr17:80096961 T/A cg07393940 chr7:158741817 NA -0.57 -7.02 -0.35 1.21e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2075371 0.933 rs1421480 chr7:133958114 A/C cg20476274 chr7:133979776 SLC35B4 0.75 12.92 0.57 2.25e-31 Mean platelet volume; LIHC cis rs77637988 0.577 rs6705802 chr2:48603483 A/C cg00032884 chr2:48540671 FOXN2 0.4 6.17 0.32 1.93e-9 Joint mobility (Beighton score); LIHC cis rs17106184 1.000 rs12078434 chr1:51393645 C/G cg07174182 chr1:51127561 FAF1 -0.72 -7.98 -0.4 2.29e-14 Type 2 diabetes; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg02990361 chr1:107599529 PRMT6 0.65 10.9 0.51 6.04e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11761441 0.669 rs13241486 chr7:79536 G/C cg25149888 chr7:81075 NA 0.39 9.23 0.45 2.87e-18 Alzheimer's disease in APOE e4- carriers; LIHC cis rs11148252 0.538 rs2296348 chr13:52710136 T/G cg12458913 chr13:53173898 NA 0.35 6.01 0.31 4.79e-9 Lewy body disease; LIHC cis rs370915 0.890 rs1425952 chr4:187833545 A/G cg19519643 chr4:187840862 NA -0.55 -9.41 -0.45 7.27e-19 Gout; LIHC cis rs6754311 0.731 rs3769005 chr2:136603366 C/G cg15123519 chr2:136567270 LCT 0.41 8.58 0.42 3.34e-16 Mosquito bite size; LIHC cis rs2228479 0.717 rs12917681 chr16:89810941 C/A cg19635926 chr16:89946313 TCF25 0.46 6.0 0.31 5.11e-9 Skin colour saturation; LIHC trans rs7618501 0.966 rs13063621 chr3:49821625 T/C cg21659725 chr3:3221576 CRBN 0.98 19.05 0.72 1.11e-55 Intelligence (multi-trait analysis); LIHC cis rs7677751 0.806 rs890203 chr4:55097405 A/C cg17187183 chr4:55093834 PDGFRA 0.68 8.53 0.42 4.89e-16 Corneal astigmatism; LIHC cis rs2439831 0.850 rs8042868 chr15:43939642 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.33 0.41 1.94e-15 Lung cancer in ever smokers; LIHC cis rs2346177 0.519 rs35509718 chr2:46696793 T/C cg02822958 chr2:46747628 ATP6V1E2 0.51 7.56 0.38 3.86e-13 HDL cholesterol; LIHC cis rs67311347 0.911 rs6775936 chr3:40377399 T/G cg18306943 chr3:40428807 ENTPD3 0.34 5.74 0.3 2.07e-8 Renal cell carcinoma; LIHC cis rs74417235 0.684 rs7723610 chr5:154053349 A/C cg25588787 chr5:154027256 NA 0.39 6.03 0.31 4.36e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs4700695 0.920 rs251303 chr5:65248753 A/C cg21114390 chr5:65439923 SFRS12 0.44 5.77 0.3 1.8e-8 Facial morphology (factor 19); LIHC cis rs208520 0.507 rs3903670 chr6:66812183 T/C cg07460842 chr6:66804631 NA -1.03 -20.09 -0.74 7.46e-60 Exhaled nitric oxide output; LIHC cis rs16828019 0.640 rs1140227 chr1:41493811 C/T cg20697417 chr1:41786797 NA 0.31 5.78 0.3 1.71e-8 Intelligence (multi-trait analysis); LIHC trans rs7246657 0.943 rs28402338 chr19:37833923 G/A cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs12971120 0.947 rs34676212 chr18:72170006 A/G cg26446133 chr18:72167187 CNDP2 -0.79 -15.89 -0.65 5.96e-43 Refractive error; LIHC cis rs861020 0.771 rs654470 chr1:210014093 A/T cg05527609 chr1:210001259 C1orf107 0.99 16.1 0.66 8.61e-44 Orofacial clefts; LIHC trans rs13202860 0.730 rs55965170 chr6:87191762 C/A cg27326224 chr7:950474 ADAP1 -0.57 -6.32 -0.32 8.05e-10 Sexual dysfunction (female); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02992252 chr1:23857546 E2F2 -0.39 -6.28 -0.32 1.03e-9 Pancreatic cancer; LIHC cis rs7539409 0.651 rs10747407 chr1:84314754 G/A cg10977910 chr1:84465055 TTLL7 0.72 7.17 0.36 4.68e-12 Alzheimer's disease; LIHC cis rs7584330 0.554 rs729389 chr2:238425118 G/A cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs2439831 0.850 rs60883262 chr15:44076503 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.53 0.33 2.42e-10 Lung cancer in ever smokers; LIHC cis rs6430585 0.536 rs3213892 chr2:136552517 G/A cg07169764 chr2:136633963 MCM6 1.17 17.26 0.68 1.82e-48 Corneal structure; LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg26338869 chr17:61819248 STRADA 0.59 8.53 0.42 4.8e-16 Prudent dietary pattern; LIHC cis rs67460515 0.529 rs6795586 chr3:160897701 A/C cg17135325 chr3:160939158 NMD3 0.52 7.57 0.38 3.4e-13 Parkinson's disease; LIHC cis rs10791323 0.569 rs11533204 chr11:133743644 A/G cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.58e-9 Childhood ear infection; LIHC cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg09222892 chr1:25734099 RHCE -0.47 -8.68 -0.42 1.65e-16 Plateletcrit;Mean corpuscular volume; LIHC cis rs12286929 0.637 rs7125361 chr11:115080042 C/G cg04055981 chr11:115044050 NA 0.36 5.91 0.3 8.48e-9 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9902453 0.845 rs3115101 chr17:28041627 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.73 0.54 5.99e-27 Coffee consumption (cups per day); LIHC cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg05025164 chr4:1340916 KIAA1530 0.63 9.57 0.46 2.19e-19 Longevity; LIHC cis rs34172651 0.917 rs7202252 chr16:24741686 T/C cg00152838 chr16:24741724 TNRC6A 0.46 6.18 0.32 1.83e-9 Intelligence (multi-trait analysis); LIHC cis rs921968 0.541 rs10200507 chr2:219335944 C/A cg02985541 chr2:219472218 PLCD4 -0.42 -6.92 -0.35 2.24e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs67311347 0.955 rs6773383 chr3:40377412 A/T cg09455208 chr3:40491958 NA 0.32 6.41 0.33 4.95e-10 Renal cell carcinoma; LIHC cis rs9322193 0.847 rs4870054 chr6:150169538 C/T cg02462569 chr6:150064036 NUP43 -0.32 -6.9 -0.35 2.52e-11 Lung cancer; LIHC trans rs1814175 0.654 rs7482446 chr11:49779020 A/G cg15704280 chr7:45808275 SEPT13 -1.02 -23.04 -0.78 1.44e-71 Height; LIHC cis rs7772486 0.688 rs1884364 chr6:146337817 C/G cg05347473 chr6:146136440 FBXO30 0.48 7.25 0.36 2.8e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs6750795 0.569 rs1667305 chr2:232403829 A/G cg19187155 chr2:232395269 NMUR1 0.58 9.17 0.44 4.45e-18 Height; LIHC cis rs589448 1.000 rs589448 chr12:69752200 A/G cg20891283 chr12:69753455 YEATS4 0.96 22.23 0.77 2.2e-68 Cerebrospinal fluid biomarker levels; LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg13395646 chr4:1353034 KIAA1530 -0.44 -6.26 -0.32 1.15e-9 Longevity; LIHC trans rs4942242 0.663 rs7985489 chr13:44206148 T/C cg19169023 chr15:41853346 TYRO3 0.51 7.26 0.37 2.59e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs7659604 1.000 rs6846232 chr4:122664805 A/G cg19748678 chr4:122722346 EXOSC9 0.35 5.87 0.3 1.06e-8 Type 2 diabetes; LIHC cis rs4653767 1.000 rs708775 chr1:226923264 G/A cg05262829 chr1:226921576 ITPKB 0.41 7.8 0.39 7.81e-14 Parkinson's disease; LIHC cis rs7617773 0.780 rs34630841 chr3:48343261 G/A cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs2075371 0.966 rs2544225 chr7:133995838 A/C cg20476274 chr7:133979776 SLC35B4 0.74 12.24 0.55 8.17e-29 Mean platelet volume; LIHC cis rs7617480 0.616 rs9873227 chr3:48773108 G/C cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.28 0.32 1.03e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs1506636 1.000 rs7779099 chr7:123295964 C/T cg03229431 chr7:123269106 ASB15 -0.61 -12.04 -0.55 4.49e-28 Plateletcrit;Platelet count; LIHC trans rs2352908 0.786 rs10130392 chr14:49427345 A/G cg00793774 chr10:104403707 TRIM8 0.5 6.05 0.31 3.84e-9 Social communication problems; LIHC cis rs5769765 0.908 rs138867 chr22:50207703 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.68 8.36 0.41 1.65e-15 Schizophrenia; LIHC cis rs6732160 0.691 rs11886257 chr2:73416873 C/T cg24220031 chr2:73402428 NA -0.27 -5.9 -0.3 8.62e-9 Intelligence (multi-trait analysis); LIHC cis rs227584 0.663 rs2040810 chr17:42243771 C/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.6 -8.87 -0.43 4.16e-17 Bone mineral density (hip);Bone mineral density; LIHC cis rs7903847 0.642 rs11814021 chr10:99158386 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.55 -0.33 2.15e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs765787 0.530 rs2413786 chr15:45525394 C/A cg25801113 chr15:45476975 SHF 0.37 6.36 0.33 6.62e-10 Uric acid levels; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.69e-29 Prudent dietary pattern; LIHC cis rs250677 0.617 rs166106 chr5:148447061 T/C cg12140854 chr5:148520817 ABLIM3 -0.52 -5.97 -0.31 5.92e-9 Breast cancer; LIHC cis rs4595586 0.525 rs10506132 chr12:39404599 C/T cg26384229 chr12:38710491 ALG10B 0.53 6.35 0.32 6.86e-10 Morning vs. evening chronotype; LIHC trans rs62103177 0.608 rs4442895 chr18:77826399 C/G cg05926928 chr17:57297772 GDPD1 -0.55 -6.84 -0.35 3.57e-11 Opioid sensitivity; LIHC trans rs60843830 1.000 rs55946380 chr2:268293 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.54 0.46 2.84e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs35110281 0.776 rs2838338 chr21:45075582 T/C cg21573476 chr21:45109991 RRP1B -0.53 -10.22 -0.48 1.44e-21 Mean corpuscular volume; LIHC cis rs4319547 0.656 rs7135419 chr12:122911861 T/A cg23029597 chr12:123009494 RSRC2 -0.53 -7.44 -0.37 8.18e-13 Body mass index; LIHC cis rs6456156 0.565 rs12529238 chr6:167465576 G/A cg07741184 chr6:167504864 NA 0.29 7.05 0.36 1.02e-11 Primary biliary cholangitis; LIHC cis rs7613875 0.600 rs2624826 chr3:50155468 T/G cg21467203 chr3:49911342 NA 0.51 9.2 0.45 3.72e-18 Body mass index; LIHC cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.74 0.3 2.07e-8 Schizophrenia; LIHC cis rs9837602 0.529 rs793495 chr3:99507934 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -7.0 -0.35 1.32e-11 Breast cancer; LIHC trans rs73186030 0.920 rs2001548 chr3:122032789 C/T cg13973942 chr17:977984 ABR 0.47 6.29 0.32 9.96e-10 Serum parathyroid hormone levels; LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg21724239 chr8:58056113 NA 0.57 7.5 0.38 5.53e-13 Developmental language disorder (linguistic errors); LIHC cis rs2304069 0.954 rs1469691 chr5:149386716 G/A cg12661370 chr5:149340060 SLC26A2 0.5 6.08 0.31 3.23e-9 HIV-1 control; LIHC cis rs875971 0.545 rs7810213 chr7:65946579 G/C cg11764359 chr7:65958608 NA 0.59 8.21 0.41 4.58e-15 Aortic root size; LIHC cis rs17685 0.712 rs11764119 chr7:75812358 T/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.81 -0.39 7.25e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7408868 1.000 rs1548554 chr19:15277938 C/T cg02272795 chr19:15279244 NOTCH3 -0.32 -5.8 -0.3 1.53e-8 Pulse pressure; LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg13012494 chr21:47604986 C21orf56 0.39 6.12 0.31 2.54e-9 Testicular germ cell tumor; LIHC cis rs3736594 0.959 rs10209020 chr2:27980944 C/T cg27432699 chr2:27873401 GPN1 -0.43 -6.73 -0.34 7.16e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC trans rs6489882 0.872 rs7132797 chr12:113375036 A/C cg10175203 chr3:128143634 NA 0.38 6.17 0.32 1.96e-9 Chronic lymphocytic leukemia; LIHC cis rs2274273 0.840 rs10467798 chr14:55724927 C/T cg04306507 chr14:55594613 LGALS3 0.32 5.97 0.31 5.93e-9 Protein biomarker; LIHC trans rs11098499 0.863 rs1480940 chr4:120457682 T/C cg25214090 chr10:38739885 LOC399744 0.62 10.01 0.48 7.41e-21 Corneal astigmatism; LIHC cis rs2832191 0.550 rs66484040 chr21:30511691 G/A cg24692254 chr21:30365293 RNF160 -0.42 -6.63 -0.34 1.29e-10 Dental caries; LIHC cis rs765787 0.530 rs11636018 chr15:45539137 T/C cg25801113 chr15:45476975 SHF 0.36 6.14 0.32 2.26e-9 Uric acid levels; LIHC cis rs904251 0.523 rs1776455 chr6:37482923 A/T cg08126542 chr6:37504118 NA -0.36 -6.21 -0.32 1.5e-9 Cognitive performance; LIHC cis rs2297440 0.506 rs2236504 chr20:62224762 C/T cg06363034 chr20:62225388 GMEB2 -0.45 -7.6 -0.38 2.8e-13 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC cis rs9902453 0.933 rs1532042 chr17:28504389 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.05 0.44 1.07e-17 Coffee consumption (cups per day); LIHC cis rs2841277 0.708 rs28600075 chr14:105408315 T/C cg21017887 chr14:105400489 NA 0.66 12.84 0.57 4.6e-31 Rheumatoid arthritis; LIHC cis rs8005677 1.000 rs2295685 chr14:23398153 A/G cg25600027 chr14:23388339 RBM23 -0.41 -5.88 -0.3 9.6e-9 Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg26338869 chr17:61819248 STRADA 0.6 8.78 0.43 7.73e-17 Prudent dietary pattern; LIHC cis rs12586317 0.620 rs10145433 chr14:35583333 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.21 0.58 1.82e-32 Psoriasis; LIHC cis rs4911259 0.552 rs6058925 chr20:31465374 G/A cg13636640 chr20:31349939 DNMT3B -0.61 -10.78 -0.5 1.56e-23 Inflammatory bowel disease; LIHC cis rs12220238 0.908 rs10824124 chr10:75997360 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.25 0.32 1.24e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7589728 1.000 rs11893832 chr2:88507537 G/C cg07952391 chr2:88470173 THNSL2 0.77 7.14 0.36 5.78e-12 Plasma clusterin levels; LIHC cis rs1878931 0.580 rs3848355 chr16:3407489 A/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.84 14.75 0.62 1.81e-38 Body mass index (adult); LIHC cis rs6121246 0.697 rs45557936 chr20:30226690 G/A cg13852791 chr20:30311386 BCL2L1 0.82 8.28 0.41 2.77e-15 Mean corpuscular hemoglobin; LIHC cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg18230493 chr5:56204884 C5orf35 -0.46 -6.36 -0.33 6.64e-10 Initial pursuit acceleration; LIHC trans rs2243480 0.764 rs2460423 chr7:65601216 A/T cg10756647 chr7:56101905 PSPH 1.1 13.4 0.59 3.3e-33 Diabetic kidney disease; LIHC cis rs6684514 0.961 rs12029695 chr1:156299847 C/T cg16558208 chr1:156270281 VHLL 0.54 10.23 0.48 1.34e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg02018176 chr4:1364513 KIAA1530 0.43 5.89 0.3 9.45e-9 Longevity; LIHC cis rs4407350 0.806 rs5765706 chr22:44909045 A/G cg26276947 chr22:44892394 LDOC1L 0.34 6.56 0.33 1.99e-10 Intelligence (multi-trait analysis); LIHC cis rs3020736 0.500 rs2413672 chr22:42513261 C/T cg15557168 chr22:42548783 NA 0.43 6.78 0.34 5.3e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs2932538 0.922 rs2932535 chr1:113201412 G/C cg22162597 chr1:113214053 CAPZA1 -0.73 -11.27 -0.52 2.84e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs67311347 0.605 rs1880762 chr3:40283215 A/G cg13409248 chr3:40428643 ENTPD3 0.43 6.87 0.35 3.03e-11 Renal cell carcinoma; LIHC cis rs787274 0.543 rs10114623 chr9:115631360 G/A cg13803584 chr9:115635662 SNX30 -0.64 -9.1 -0.44 7.77e-18 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9733 0.526 rs11204696 chr1:150658721 T/C cg13175981 chr1:150552382 MCL1 -0.44 -5.99 -0.31 5.37e-9 Tonsillectomy; LIHC cis rs288342 0.832 rs288283 chr2:183642628 C/T cg02625481 chr2:183667124 NA -0.29 -5.91 -0.3 8.39e-9 Recurrent major depressive disorder; LIHC cis rs6430585 0.528 rs309159 chr2:136684940 C/T cg07169764 chr2:136633963 MCM6 1.0 15.34 0.64 8.56e-41 Corneal structure; LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg07677032 chr17:61819896 STRADA -0.41 -5.93 -0.31 7.46e-9 Prudent dietary pattern; LIHC cis rs10089 1.000 rs59484271 chr5:127503781 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.52 0.33 2.52e-10 Ileal carcinoids; LIHC cis rs9918079 0.560 rs4270584 chr4:15600799 A/G cg18470593 chr4:15471377 CC2D2A 0.4 6.06 0.31 3.69e-9 Obesity-related traits; LIHC cis rs2404602 0.684 rs1011083 chr15:77007527 C/T cg23625390 chr15:77176239 SCAPER -0.55 -9.4 -0.45 8.37e-19 Blood metabolite levels; LIHC cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg02290350 chr8:58132656 NA -0.46 -9.0 -0.44 1.63e-17 Developmental language disorder (linguistic errors); LIHC cis rs7592578 0.771 rs75579212 chr2:191376575 C/T cg10560079 chr2:191398806 TMEM194B -0.84 -12.26 -0.55 6.96e-29 Diastolic blood pressure; LIHC cis rs17376456 0.757 rs10476591 chr5:93333723 G/C cg25358565 chr5:93447407 FAM172A 1.03 9.61 0.46 1.58e-19 Diabetic retinopathy; LIHC cis rs7208859 0.673 rs79541516 chr17:29240583 C/T cg14067834 chr17:29058358 SUZ12P 0.63 6.06 0.31 3.54e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10870270 1.000 rs10781564 chr10:133757922 A/G cg08754478 chr10:133766260 PPP2R2D -0.55 -8.12 -0.4 8.62e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs4908768 0.501 rs11121199 chr1:8600192 G/A cg20416874 chr1:8611966 RERE -0.68 -14.63 -0.62 5.32e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7666738 0.546 rs34159897 chr4:98787367 T/C cg05340658 chr4:99064831 C4orf37 0.51 6.7 0.34 8.84e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs864643 0.945 rs583083 chr3:39550445 C/T cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs739401 0.595 rs2073843 chr11:2970855 A/G cg20651018 chr11:3035856 CARS -0.38 -6.34 -0.32 7.19e-10 Longevity; LIHC cis rs7572733 0.534 rs1607374 chr2:198800440 A/G cg03934865 chr2:198174659 NA 0.45 6.4 0.33 5.06e-10 Dermatomyositis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07454192 chr8:74888262 TMEM70 0.38 6.34 0.32 7.19e-10 Cognitive function; LIHC cis rs1577917 0.958 rs12213431 chr6:86500956 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.21 -0.41 4.6e-15 Response to antipsychotic treatment; LIHC cis rs11971779 0.680 rs2355787 chr7:139089928 G/T cg07862535 chr7:139043722 LUC7L2 -0.6 -10.35 -0.49 5.1e-22 Diisocyanate-induced asthma; LIHC cis rs2857078 0.654 rs9896789 chr17:42314567 C/T cg09913183 chr17:42254507 C17orf65;ASB16 0.57 8.52 0.42 5.17e-16 Red cell distribution width;Reticulocyte count; LIHC trans rs1624005 1.000 rs2481764 chr14:43381455 T/A cg11960719 chr5:1510684 LPCAT1 -0.35 -6.21 -0.32 1.54e-9 Methotrexate-induced interstitial lung disease in rheumatoid arthritis; LIHC cis rs6754311 0.731 rs3754686 chr2:136603276 T/C cg15123519 chr2:136567270 LCT 0.44 9.02 0.44 1.35e-17 Mosquito bite size; LIHC cis rs35110281 0.720 rs162376 chr21:44926759 G/T cg01579765 chr21:45077557 HSF2BP 0.37 6.72 0.34 7.76e-11 Mean corpuscular volume; LIHC cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.64 0.38 2.15e-13 Bipolar disorder; LIHC cis rs7412746 0.646 rs1972060 chr1:150937594 T/C cg17724175 chr1:150552817 MCL1 0.38 7.47 0.37 6.67e-13 Melanoma; LIHC cis rs1005277 0.579 rs2800485 chr10:38542588 G/A cg25427524 chr10:38739819 LOC399744 -0.76 -15.25 -0.64 2.01e-40 Extrinsic epigenetic age acceleration; LIHC trans rs9834975 0.544 rs9917729 chr3:122285701 A/T cg18228109 chr6:162684441 PARK2 0.34 6.07 0.31 3.48e-9 Diastolic blood pressure; LIHC cis rs477692 1.000 rs7475154 chr10:131440584 C/T cg19680672 chr10:131412579 MGMT 0.43 6.53 0.33 2.4e-10 Response to temozolomide; LIHC cis rs7772486 0.754 rs6915718 chr6:146100676 A/G cg23711669 chr6:146136114 FBXO30 -0.74 -13.18 -0.58 2.24e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs1215050 0.791 rs1530904 chr4:98805436 A/G cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.86e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg19318889 chr4:1322082 MAEA 0.47 6.69 0.34 8.94e-11 Obesity-related traits; LIHC cis rs12497850 0.931 rs9846123 chr3:49088112 C/T cg07636037 chr3:49044803 WDR6 -0.93 -17.16 -0.68 4.78e-48 Parkinson's disease; LIHC cis rs12464559 0.579 rs11682909 chr2:152651592 A/G cg01189475 chr2:152685088 ARL5A 0.64 7.48 0.38 6.16e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs1577917 0.959 rs16876540 chr6:86612519 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.55 -0.5 1.01e-22 Response to antipsychotic treatment; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg26246133 chr11:93276703 C11orf75 0.47 6.58 0.34 1.8e-10 Immature fraction of reticulocytes; LIHC cis rs875971 1.000 rs6945843 chr7:65734783 G/A cg11764359 chr7:65958608 NA -0.91 -16.88 -0.67 6.07e-47 Aortic root size; LIHC cis rs9309473 0.687 rs11693531 chr2:73608614 C/G cg20560298 chr2:73613845 ALMS1 -0.46 -7.31 -0.37 1.85e-12 Metabolite levels; LIHC cis rs79149102 0.579 rs12591994 chr15:75320306 A/G cg17294928 chr15:75287854 SCAMP5 -0.5 -6.26 -0.32 1.16e-9 Lung cancer; LIHC cis rs13161895 1.000 rs1102191 chr5:179416210 C/T cg06664874 chr5:179499304 RNF130 0.57 7.02 0.35 1.21e-11 LDL cholesterol; LIHC cis rs9911578 0.835 rs58647683 chr17:56483194 T/C cg05425664 chr17:57184151 TRIM37 0.57 8.19 0.41 5.15e-15 Intelligence (multi-trait analysis); LIHC cis rs700651 0.789 rs892514 chr2:198905270 T/C cg10820045 chr2:198174542 NA 0.44 6.47 0.33 3.38e-10 Intracranial aneurysm; LIHC cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg11502198 chr6:26597334 ABT1 0.64 10.12 0.48 3.23e-21 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.691 rs9996494 chr4:120238880 C/A cg25214090 chr10:38739885 LOC399744 0.52 8.5 0.42 6.06e-16 Corneal astigmatism; LIHC cis rs9768139 0.935 rs7800718 chr7:158121878 G/A cg25566285 chr7:158114605 PTPRN2 -0.26 -7.69 -0.38 1.63e-13 Calcium levels; LIHC cis rs2991971 0.810 rs6657237 chr1:45920108 A/T cg24296786 chr1:45957014 TESK2 -0.53 -8.18 -0.4 5.63e-15 High light scatter reticulocyte count; LIHC cis rs9611519 0.929 rs12484477 chr22:41429084 G/A cg03806693 chr22:41940476 POLR3H -0.69 -7.72 -0.39 1.27e-13 Neuroticism; LIHC cis rs11167764 0.945 rs891991 chr5:141484977 A/T cg23435118 chr5:141488016 NDFIP1 -0.43 -6.01 -0.31 4.86e-9 Crohn's disease; LIHC cis rs7918232 0.607 rs1755401 chr10:27405763 A/C cg14240646 chr10:27532245 ACBD5 -0.83 -6.87 -0.35 3.07e-11 Breast cancer; LIHC trans rs8002861 0.754 rs4053664 chr13:44429172 A/C cg17145862 chr1:211918768 LPGAT1 0.58 10.69 0.5 3.2e-23 Leprosy; LIHC cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg08219700 chr8:58056026 NA 0.44 5.75 0.3 1.94e-8 Developmental language disorder (linguistic errors); LIHC cis rs2845885 0.793 rs57779243 chr11:63882363 G/T cg18375707 chr11:64034959 PLCB3 -0.52 -7.89 -0.39 4.08e-14 Body mass index; LIHC cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.33 0.41 1.99e-15 Platelet count; LIHC cis rs60871478 0.541 rs56964970 chr7:910791 G/C cg05535760 chr7:792225 HEATR2 -0.81 -6.56 -0.33 1.99e-10 Cerebrospinal P-tau181p levels; LIHC cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg18230493 chr5:56204884 C5orf35 -0.44 -6.08 -0.31 3.29e-9 Initial pursuit acceleration; LIHC cis rs2742417 0.624 rs2673068 chr3:45768981 G/A cg04837898 chr3:45731254 SACM1L -0.46 -7.62 -0.38 2.56e-13 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg20295408 chr7:1910781 MAD1L1 -0.46 -6.77 -0.34 5.68e-11 Bipolar disorder and schizophrenia; LIHC cis rs10504229 1.000 rs72652906 chr8:58188360 C/A cg21724239 chr8:58056113 NA 0.46 6.2 0.32 1.64e-9 Developmental language disorder (linguistic errors); LIHC cis rs2455799 0.613 rs7620787 chr3:15882826 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.96e-13 Mean platelet volume; LIHC cis rs9611519 1.000 rs9611520 chr22:41613303 C/T cg03806693 chr22:41940476 POLR3H -0.7 -7.82 -0.39 6.64e-14 Neuroticism; LIHC cis rs910316 0.967 rs8007539 chr14:75664953 T/C cg08847533 chr14:75593920 NEK9 -0.84 -17.3 -0.68 1.29e-48 Height; LIHC cis rs5769765 0.865 rs3788730 chr22:50244695 C/T cg02269571 chr22:50332266 NA 0.59 8.4 0.41 1.23e-15 Schizophrenia; LIHC cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.99 0.51 2.87e-24 Platelet count; LIHC cis rs7772486 0.790 rs9390365 chr6:146235626 A/G cg23711669 chr6:146136114 FBXO30 -0.71 -12.42 -0.56 1.7e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs1348850 0.526 rs4144278 chr2:178412378 C/T cg27490568 chr2:178487706 NA 1.0 11.01 0.51 2.49e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg27170947 chr2:26402098 FAM59B -0.72 -8.66 -0.42 1.85e-16 Gut microbiome composition (summer); LIHC cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg05368731 chr17:41323189 NBR1 0.72 12.26 0.55 6.95e-29 Menopause (age at onset); LIHC cis rs8081395 0.741 rs1292051 chr17:57963923 G/A cg13753209 chr17:57696993 CLTC 0.38 5.71 0.3 2.43e-8 White blood cell count; LIHC cis rs6785206 0.667 rs6439139 chr3:128410285 T/C cg16766828 chr3:128327626 NA -0.63 -6.85 -0.35 3.54e-11 Lymphocyte percentage of white cells; LIHC cis rs7945705 0.935 rs2568061 chr11:8886260 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -9.35 -0.45 1.22e-18 Hemoglobin concentration; LIHC trans rs61931739 0.517 rs1197562 chr12:34122037 G/A cg26384229 chr12:38710491 ALG10B 0.46 6.46 0.33 3.6e-10 Morning vs. evening chronotype; LIHC cis rs875971 1.000 rs1565531 chr7:65663113 T/A cg11764359 chr7:65958608 NA -0.88 -15.37 -0.64 6.43e-41 Aortic root size; LIHC trans rs465757 1.000 rs465757 chr20:15580283 A/G cg18760920 chr15:68177265 NA -0.49 -6.13 -0.31 2.39e-9 Interleukin-10 levels; LIHC cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg06418219 chr1:154948305 SHC1;CKS1B -0.48 -6.94 -0.35 1.98e-11 Prostate cancer; LIHC cis rs908922 0.676 rs945789 chr1:152512705 C/A cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27220681 chr17:685915 RNMTL1;GLOD4 0.51 7.64 0.38 2.16e-13 Lung function (FEV1/FVC); LIHC cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg05564831 chr3:52568323 NT5DC2 0.36 5.94 0.31 7.12e-9 Bipolar disorder; LIHC cis rs60871478 0.730 rs13222476 chr7:826630 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.52 5.98 0.31 5.61e-9 Cerebrospinal P-tau181p levels; LIHC cis rs8074751 0.625 rs6504335 chr17:63634508 G/A cg04531363 chr17:63634484 CCDC46 0.32 5.75 0.3 1.95e-8 Attention deficit hyperactivity disorder; LIHC cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg24531977 chr5:56204891 C5orf35 0.65 9.39 0.45 8.52e-19 Initial pursuit acceleration; LIHC cis rs10508774 1.000 rs12415588 chr10:32761592 C/A cg01819863 chr10:32635814 EPC1 0.65 6.08 0.31 3.28e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6831352 0.918 rs29001195 chr4:100054244 G/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs5758511 0.680 rs1033460 chr22:42619308 A/G cg00645731 chr22:42541494 CYP2D7P1 0.54 8.63 0.42 2.42e-16 Birth weight; LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.09 -0.31 3.09e-9 Total body bone mineral density; LIHC cis rs4240897 0.935 rs2236055 chr1:12042261 A/G cg13216073 chr1:12042593 MFN2 0.51 8.27 0.41 2.98e-15 Tuberculosis; LIHC cis rs763121 0.889 rs9607557 chr22:39040279 G/A cg21395723 chr22:39101663 GTPBP1 0.38 6.39 0.33 5.36e-10 Menopause (age at onset); LIHC cis rs2066819 1.000 rs2695789 chr12:56694261 C/A cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Psoriasis vulgaris; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg03987003 chr1:145516092 GNRHR2;PEX11B -0.49 -6.1 -0.31 2.82e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC trans rs208520 0.661 rs207099 chr6:66796373 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.11 -0.44 7.04e-18 Exhaled nitric oxide output; LIHC cis rs367615 0.552 rs2963023 chr5:108730070 C/T cg17395555 chr5:108820864 NA -0.28 -5.96 -0.31 6.22e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs6570726 0.643 rs9403735 chr6:145936591 C/T cg23711669 chr6:146136114 FBXO30 0.73 12.25 0.55 7.78e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg03264133 chr6:25882463 NA -0.69 -9.27 -0.45 2.16e-18 Intelligence (multi-trait analysis); LIHC cis rs8027181 0.839 rs8025333 chr15:73025121 A/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 7.96 0.4 2.61e-14 Triglyceride levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13552506 chr1:946444 NA 0.43 6.17 0.32 1.97e-9 Longevity; LIHC cis rs892961 0.899 rs35217221 chr17:75412385 G/A cg01320579 chr17:75405842 SEPT9 0.54 7.72 0.39 1.31e-13 Airflow obstruction; LIHC cis rs711245 0.637 rs11894187 chr2:36781708 T/A cg09467607 chr2:36825704 FEZ2 0.49 7.21 0.36 3.51e-12 Height; LIHC cis rs17401966 0.931 rs1555849 chr1:10400602 G/T cg19773385 chr1:10388646 KIF1B 0.4 6.96 0.35 1.74e-11 Hepatocellular carcinoma; LIHC cis rs7264396 0.563 rs2425121 chr20:34326186 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.68 -0.43 1.59e-16 Total cholesterol levels; LIHC cis rs965469 1.000 rs6051808 chr20:3350697 A/T cg25506879 chr20:3388711 C20orf194 -0.54 -6.51 -0.33 2.65e-10 IFN-related cytopenia; LIHC cis rs875971 0.540 rs736270 chr7:65428822 T/C cg26939375 chr7:64535504 NA 0.47 7.16 0.36 4.84e-12 Aortic root size; LIHC cis rs9517313 0.707 rs9517298 chr13:99095003 C/T cg07423050 chr13:99094983 FARP1 -0.67 -12.68 -0.57 1.77e-30 Neuroticism; LIHC cis rs1048238 0.506 rs848212 chr1:16263452 A/G cg00529422 chr1:16285251 ZBTB17 0.34 6.49 0.33 3.04e-10 Systolic blood pressure; LIHC cis rs9467773 1.000 rs6940188 chr6:26562029 G/C cg09904177 chr6:26538194 HMGN4 0.65 13.64 0.59 3.82e-34 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.954 rs71614438 chr4:120371252 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 7.9 0.39 3.85e-14 Platelet count; LIHC trans rs2797160 0.904 rs1612274 chr6:126014907 C/A cg05039488 chr6:79577232 IRAK1BP1 0.48 6.77 0.34 5.62e-11 Endometrial cancer; LIHC trans rs7937682 0.889 rs10789844 chr11:111579109 A/T cg18187862 chr3:45730750 SACM1L 0.57 6.76 0.34 6.03e-11 Primary sclerosing cholangitis; LIHC cis rs7927771 0.524 rs10838746 chr11:47706291 A/G cg20307385 chr11:47447363 PSMC3 0.77 11.58 0.53 2.15e-26 Subjective well-being; LIHC cis rs1401999 0.934 rs1132776 chr3:183696402 A/G cg05044414 chr3:183734942 ABCC5 0.34 5.99 0.31 5.34e-9 Anterior chamber depth; LIHC cis rs12477438 0.520 rs4347885 chr2:99804007 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 13.92 0.6 3.22e-35 Chronic sinus infection; LIHC cis rs703842 1.000 rs11172344 chr12:58193448 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.82 13.59 0.59 5.99e-34 Multiple sclerosis; LIHC cis rs28735056 0.933 rs499472 chr18:77589759 C/T cg20368463 chr18:77673604 PQLC1 -0.38 -6.72 -0.34 7.74e-11 Schizophrenia; LIHC cis rs7103411 0.592 rs11030087 chr11:27646246 T/C cg18117895 chr11:27722066 BDNF -0.46 -6.59 -0.34 1.66e-10 Menarche (age at onset);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.62 0.34 1.4e-10 Bipolar disorder; LIHC cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg11890956 chr21:40555474 PSMG1 0.55 9.15 0.44 5.29e-18 Cognitive function; LIHC trans rs11098499 0.863 rs17050695 chr4:120489527 G/T cg25214090 chr10:38739885 LOC399744 0.54 8.78 0.43 8.01e-17 Corneal astigmatism; LIHC cis rs1059312 0.966 rs35907548 chr12:129282180 T/C cg09035930 chr12:129282057 SLC15A4 0.68 12.97 0.57 1.41e-31 Systemic lupus erythematosus; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10029411 chr13:50746245 FAM10A4 0.37 6.09 0.31 3.05e-9 Pancreatic cancer; LIHC cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg13395646 chr4:1353034 KIAA1530 0.42 6.54 0.33 2.23e-10 Obesity-related traits; LIHC cis rs637571 0.522 rs503524 chr11:65751764 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.2 0.45 3.58e-18 Eosinophil percentage of white cells; LIHC cis rs7116495 0.609 rs4245463 chr11:71743213 C/A cg10381502 chr11:71823885 C11orf51 -1.07 -9.09 -0.44 8.45e-18 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs760805 1.000 rs10903115 chr1:25261696 A/G cg22509179 chr1:25234806 RUNX3 -0.4 -8.69 -0.43 1.55e-16 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9899728 0.572 rs4365317 chr17:73059820 C/G cg27626185 chr17:73056755 KCTD2 -0.66 -11.84 -0.54 2.44e-27 Alzheimer's disease or small vessel stroke; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg14195377 chr11:60928647 VPS37C -0.4 -6.26 -0.32 1.17e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1577917 0.958 rs2660576 chr6:86651603 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.79 -0.39 8.24e-14 Response to antipsychotic treatment; LIHC cis rs34779708 0.966 rs11592567 chr10:35409369 C/T cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1552244 0.816 rs56271597 chr3:10042790 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.77 10.36 0.49 4.53e-22 Alzheimer's disease; LIHC cis rs9583531 0.657 rs7337126 chr13:111376788 A/G cg15841412 chr13:111365552 ING1 0.5 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs1055129 0.537 rs2467100 chr17:73949038 C/G cg08125733 chr17:73851984 WBP2 0.54 8.41 0.41 1.12e-15 White matter hyperintensity burden; LIHC cis rs17539620 0.628 rs11541340 chr6:154831572 C/G cg17771515 chr6:154831774 CNKSR3 0.59 6.25 0.32 1.19e-9 Lipoprotein (a) levels; LIHC trans rs208520 0.526 rs6913344 chr6:66754285 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -15.19 -0.63 3.33e-40 Exhaled nitric oxide output; LIHC cis rs7833790 0.676 rs7834555 chr8:82697625 A/G cg17211192 chr8:82754475 SNX16 -0.52 -9.25 -0.45 2.48e-18 Diastolic blood pressure; LIHC cis rs2806561 0.808 rs4654834 chr1:23364919 T/C cg19743168 chr1:23544995 NA -0.39 -7.15 -0.36 5.27e-12 Height; LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg08219700 chr8:58056026 NA 0.52 7.14 0.36 5.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs67460515 0.563 rs13071892 chr3:160817877 A/C cg17135325 chr3:160939158 NMD3 0.56 7.77 0.39 9.21e-14 Parkinson's disease; LIHC cis rs6752107 1.000 rs34123137 chr2:234167881 T/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.34 0.41 1.9e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs5770917 1.000 rs115743514 chr22:51011933 T/C cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.48 -5.91 -0.3 8.28e-9 Narcolepsy; LIHC cis rs1577917 0.958 rs1337843 chr6:86675545 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.72 -0.39 1.33e-13 Response to antipsychotic treatment; LIHC cis rs2573652 0.698 rs12916269 chr15:100530216 A/T cg09918751 chr15:100517450 ADAMTS17 0.74 13.39 0.59 3.61e-33 Height; LIHC cis rs28830936 0.934 rs2412641 chr15:42124399 G/A cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.09 -0.31 3.05e-9 Diastolic blood pressure; LIHC cis rs763121 0.853 rs138704 chr22:39133410 A/G cg21395723 chr22:39101663 GTPBP1 0.35 5.74 0.3 2.06e-8 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04650786 chr6:108395545 OSTM1 0.41 6.19 0.32 1.71e-9 Pancreatic cancer; LIHC cis rs11718455 0.960 rs17076255 chr3:44002093 C/T cg08738300 chr3:44038990 NA 0.51 8.82 0.43 5.97e-17 Coronary artery disease; LIHC cis rs12980942 0.591 rs11879429 chr19:41757444 G/A cg25627403 chr19:41769009 HNRNPUL1 0.58 6.99 0.35 1.47e-11 Coronary artery disease; LIHC cis rs10791097 0.694 rs4457753 chr11:130755575 A/G cg14779329 chr11:130786720 SNX19 0.42 6.4 0.33 5.12e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09469394 chr2:61243988 PEX13;PUS10 0.44 6.29 0.32 9.61e-10 Cognitive function; LIHC cis rs8016982 0.589 rs12586249 chr14:81701004 T/C cg01989461 chr14:81687754 GTF2A1 -0.45 -7.48 -0.38 6.13e-13 Schizophrenia; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.584 rs2305833 chr2:219305404 G/C cg02176678 chr2:219576539 TTLL4 0.42 6.25 0.32 1.22e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7727544 0.684 rs2631363 chr5:131707095 A/G cg24060327 chr5:131705240 SLC22A5 0.6 8.81 0.43 6.55e-17 Blood metabolite levels; LIHC cis rs2439831 0.850 rs11070408 chr15:44034788 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.49 0.33 2.97e-10 Lung cancer in ever smokers; LIHC cis rs12188164 0.525 rs1114665 chr5:452247 C/T cg07599136 chr5:415885 AHRR 0.39 6.54 0.33 2.21e-10 Cystic fibrosis severity; LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg08677398 chr8:58056175 NA 0.4 5.81 0.3 1.39e-8 Developmental language disorder (linguistic errors); LIHC cis rs7044106 0.762 rs3903886 chr9:123383646 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.49 -7.4 -0.37 1.04e-12 Hip circumference adjusted for BMI; LIHC cis rs311392 0.966 rs425548 chr8:55087468 C/T cg11783602 chr8:55087084 NA -0.34 -6.57 -0.33 1.92e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs17102884 0.587 rs6574190 chr14:75167015 G/A cg08847533 chr14:75593920 NEK9 0.43 6.61 0.34 1.44e-10 Neuroticism; LIHC cis rs7617773 0.817 rs6800492 chr3:48323890 G/A cg11946769 chr3:48343235 NME6 0.88 11.18 0.52 6.06e-25 Coronary artery disease; LIHC cis rs919433 0.680 rs7605813 chr2:198375329 C/G cg03934865 chr2:198174659 NA 0.54 8.26 0.41 3.32e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1005277 0.579 rs2504148 chr10:38400788 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs2273156 1.000 rs36112862 chr14:35478433 C/T cg16230307 chr14:35515116 FAM177A1 -0.41 -6.05 -0.31 3.88e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs655641 1.000 rs528109 chr11:85715853 C/T cg09030501 chr11:85779252 PICALM -0.49 -6.07 -0.31 3.42e-9 Platelet count; LIHC cis rs4788570 0.615 rs6499526 chr16:71648299 C/T cg06353428 chr16:71660113 MARVELD3 1.4 13.93 0.6 2.91e-35 Intelligence (multi-trait analysis); LIHC cis rs11690935 1.000 rs6721680 chr2:172543913 G/T cg13550731 chr2:172543902 DYNC1I2 0.94 19.04 0.72 1.27e-55 Schizophrenia; LIHC cis rs7091068 0.536 rs7893369 chr10:95410147 A/G cg20715218 chr10:95462985 C10orf4 0.54 8.42 0.41 1.07e-15 Urinary tract infection frequency; LIHC cis rs6570726 0.791 rs418701 chr6:145889992 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.27 0.32 1.07e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs796364 0.760 rs11690371 chr2:200989616 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.64 -7.01 -0.35 1.31e-11 Schizophrenia; LIHC cis rs67311347 1.000 rs7636719 chr3:40432084 C/T cg13409248 chr3:40428643 ENTPD3 0.4 6.56 0.33 2.02e-10 Renal cell carcinoma; LIHC cis rs4908768 0.539 rs922366 chr1:8653733 C/A cg20416874 chr1:8611966 RERE -0.62 -11.25 -0.52 3.49e-25 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg00166722 chr3:10149974 C3orf24 0.47 5.75 0.3 1.94e-8 Alzheimer's disease; LIHC trans rs6934970 1.000 rs9384846 chr6:113124583 C/T cg02462569 chr6:150064036 NUP43 -0.46 -6.09 -0.31 3.1e-9 Bipolar disorder (body mass index interaction); LIHC cis rs637571 0.544 rs617791 chr11:65702523 C/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.43 6.49 0.33 3.05e-10 Eosinophil percentage of white cells; LIHC cis rs9918079 0.560 rs4270584 chr4:15600799 A/G cg16509355 chr4:15471240 CC2D2A 0.5 7.82 0.39 6.46e-14 Obesity-related traits; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg11494091 chr17:61959527 GH2 0.36 5.99 0.31 5.44e-9 Height; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg26338869 chr17:61819248 STRADA 0.61 8.94 0.44 2.57e-17 Prudent dietary pattern; LIHC cis rs2439831 0.717 rs690170 chr15:43810422 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.66 8.79 0.43 7.51e-17 Lung cancer in ever smokers; LIHC cis rs2576037 0.526 rs658756 chr18:44431832 A/G cg19077165 chr18:44547161 KATNAL2 -0.42 -6.44 -0.33 3.98e-10 Personality dimensions; LIHC cis rs7945705 0.902 rs2012696 chr11:8995818 A/C cg12365402 chr11:9010492 NRIP3 0.33 8.5 0.42 5.86e-16 Hemoglobin concentration; LIHC cis rs9309473 0.950 rs17009149 chr2:73790368 T/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs3749237 0.595 rs6784820 chr3:49450864 C/T cg03060546 chr3:49711283 APEH -0.61 -9.92 -0.47 1.51e-20 Resting heart rate; LIHC cis rs3815700 1.000 rs7248273 chr19:33096816 C/T cg02997394 chr19:33096574 ANKRD27 0.66 7.88 0.39 4.28e-14 Eosinophilic esophagitis; LIHC cis rs56235845 0.694 rs11949401 chr5:176765989 A/G cg17509989 chr5:176798049 RGS14 0.59 7.78 0.39 8.4e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs9393692 0.645 rs2179152 chr6:26325888 T/C cg00631329 chr6:26305371 NA -0.5 -7.91 -0.39 3.52e-14 Educational attainment; LIHC cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.27 -0.37 2.47e-12 Bipolar disorder; LIHC cis rs1506636 0.927 rs11983604 chr7:123329754 T/G cg03229431 chr7:123269106 ASB15 -0.6 -11.96 -0.54 8.95e-28 Plateletcrit;Platelet count; LIHC cis rs72781680 0.756 rs2712059 chr2:24020539 T/C cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.07e-9 Lymphocyte counts; LIHC cis rs2073300 0.609 rs79250740 chr20:23417165 G/A cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.49e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9309473 0.898 rs10185080 chr2:73797507 C/A cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs3806843 0.932 rs2563257 chr5:140140529 A/G cg19875535 chr5:140030758 IK -0.37 -5.98 -0.31 5.72e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs6964587 0.967 rs6465340 chr7:91588664 G/A cg17063962 chr7:91808500 NA 1.0 18.93 0.72 3.6e-55 Breast cancer; LIHC cis rs9790314 0.967 rs7623206 chr3:160971518 G/A cg03342759 chr3:160939853 NMD3 -0.73 -8.98 -0.44 1.89e-17 Morning vs. evening chronotype; LIHC cis rs6963495 0.818 rs73192149 chr7:105210910 A/G cg19920283 chr7:105172520 RINT1 0.67 6.04 0.31 3.95e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6594499 0.872 rs10059658 chr5:110452815 T/C cg04022379 chr5:110408740 TSLP 0.49 8.16 0.4 6.26e-15 Allergic disease (asthma, hay fever or eczema); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04098458 chr2:149402448 EPC2 -0.44 -6.29 -0.32 9.68e-10 Cognitive function; LIHC cis rs8114671 0.836 rs6141526 chr20:33615255 G/T cg07148914 chr20:33460835 GGT7 -0.55 -8.36 -0.41 1.6e-15 Height; LIHC cis rs7666738 0.712 rs11731393 chr4:98859070 G/C cg05340658 chr4:99064831 C4orf37 0.5 5.79 0.3 1.6e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs7769051 0.711 rs7770081 chr6:133089569 G/T cg22852734 chr6:133119734 C6orf192 0.86 8.64 0.42 2.17e-16 Type 2 diabetes nephropathy; LIHC cis rs12188164 0.543 rs890972 chr5:462465 C/A cg08916839 chr5:415575 AHRR 0.29 6.31 0.32 8.64e-10 Cystic fibrosis severity; LIHC cis rs7635838 0.859 rs9869423 chr3:11459156 G/T cg00170343 chr3:11313890 ATG7 0.44 6.76 0.34 5.97e-11 HDL cholesterol; LIHC cis rs7617773 1.000 rs6442109 chr3:48192981 G/A cg11946769 chr3:48343235 NME6 -0.65 -8.39 -0.41 1.34e-15 Coronary artery disease; LIHC cis rs1401999 0.966 rs2313212 chr3:183700928 A/G cg01324343 chr3:183735012 ABCC5 0.76 12.8 0.57 6.44e-31 Anterior chamber depth; LIHC cis rs9309473 0.607 rs1403412 chr2:73598092 T/C cg20560298 chr2:73613845 ALMS1 -0.46 -7.51 -0.38 5.23e-13 Metabolite levels; LIHC cis rs801193 1.000 rs2659909 chr7:66160279 G/A cg11764359 chr7:65958608 NA 0.71 10.46 0.49 2.16e-22 Aortic root size; LIHC cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg09323728 chr8:95962352 TP53INP1 -0.34 -7.52 -0.38 4.97e-13 Type 2 diabetes; LIHC cis rs10489202 0.683 rs7515429 chr1:168066659 A/G cg24449463 chr1:168025552 DCAF6 -0.52 -7.08 -0.36 8.23e-12 Schizophrenia; LIHC cis rs4891159 0.548 rs10782013 chr18:74128348 C/T cg24786174 chr18:74118243 ZNF516 0.84 17.59 0.69 9.04e-50 Longevity; LIHC cis rs459571 0.715 rs401826 chr9:136890591 C/T cg13789015 chr9:136890014 NCRNA00094 0.44 8.09 0.4 1.03e-14 Platelet distribution width; LIHC cis rs6545883 0.931 rs778765 chr2:61786385 A/T cg15711740 chr2:61764176 XPO1 -0.43 -6.11 -0.31 2.7e-9 Tuberculosis; LIHC cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.43 6.15 0.32 2.15e-9 Menopause (age at onset); LIHC cis rs965469 0.779 rs2207995 chr20:3294484 T/C cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs2991971 0.729 rs10890328 chr1:45905383 G/T cg15605315 chr1:45957053 TESK2 -0.49 -6.88 -0.35 2.88e-11 High light scatter reticulocyte count; LIHC cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg16405210 chr4:1374714 KIAA1530 -0.89 -14.62 -0.62 6.33e-38 Longevity; LIHC cis rs17253792 0.822 rs78395034 chr14:56069783 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg20607798 chr8:58055168 NA 0.63 7.96 0.4 2.64e-14 Developmental language disorder (linguistic errors); LIHC cis rs919433 0.680 rs2564383 chr2:198310862 A/G cg03934865 chr2:198174659 NA 0.54 8.3 0.41 2.38e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9611565 0.525 rs1883827 chr22:41703579 A/G cg03806693 chr22:41940476 POLR3H -0.73 -8.51 -0.42 5.43e-16 Vitiligo; LIHC cis rs801193 1.000 rs10274773 chr7:66133578 G/A cg11764359 chr7:65958608 NA -0.71 -10.55 -0.5 1.05e-22 Aortic root size; LIHC cis rs11148252 0.595 rs9526974 chr13:53251040 C/G cg00495681 chr13:53174319 NA 0.64 11.08 0.51 1.39e-24 Lewy body disease; LIHC cis rs763121 0.853 rs138712 chr22:39141600 C/T cg14440974 chr22:39074834 NA -0.38 -6.2 -0.32 1.62e-9 Menopause (age at onset); LIHC cis rs3020736 0.500 rs5996109 chr22:42493098 A/G cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs6952808 0.594 rs3778969 chr7:2139990 A/G cg22963979 chr7:1858916 MAD1L1 0.36 5.76 0.3 1.89e-8 Bipolar disorder and schizophrenia; LIHC cis rs56091001 0.528 rs9616387 chr22:50313219 G/A cg02269571 chr22:50332266 NA -1.12 -11.04 -0.51 2e-24 Acne (severe); LIHC cis rs9303280 0.967 rs1031458 chr17:38072173 G/T cg11212589 chr17:38028394 ZPBP2 -0.34 -6.67 -0.34 1.02e-10 Self-reported allergy; LIHC cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.88 12.97 0.57 1.45e-31 Alzheimer's disease; LIHC cis rs17818399 0.653 rs34050156 chr2:46777646 A/G cg02822958 chr2:46747628 ATP6V1E2 0.47 6.95 0.35 1.82e-11 Height; LIHC cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg02503808 chr4:7069936 GRPEL1 0.77 11.61 0.53 1.68e-26 Monocyte percentage of white cells; LIHC trans rs2270927 0.510 rs13188781 chr5:75580409 C/A cg13563193 chr19:33072644 PDCD5 0.97 9.06 0.44 9.9e-18 Mean corpuscular volume; LIHC cis rs9733 0.596 rs72702557 chr1:150680130 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11635401 chr19:17322527 MYO9B 0.45 6.77 0.34 5.48e-11 Longevity; LIHC cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg13409248 chr3:40428643 ENTPD3 0.42 6.93 0.35 2.16e-11 Renal cell carcinoma; LIHC cis rs798554 0.959 rs798556 chr7:2759002 C/A cg13628971 chr7:2884303 GNA12 0.48 6.88 0.35 2.89e-11 Height; LIHC cis rs6809651 0.524 rs4686730 chr3:185805993 C/T cg00760338 chr3:185826511 ETV5 -0.87 -12.95 -0.57 1.74e-31 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs2108622 0.727 rs12609468 chr19:15977814 A/G cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs7512552 0.839 rs832622 chr1:150392830 A/G cg15654264 chr1:150340011 RPRD2 0.69 11.23 0.52 4.11e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg18538332 chr22:24372958 LOC391322 -0.63 -9.32 -0.45 1.46e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7129220 0.588 rs34984386 chr11:10095987 A/C cg01453529 chr11:10209919 SBF2 -0.39 -6.91 -0.35 2.43e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.56 0.56 5.14e-30 Prudent dietary pattern; LIHC cis rs10883723 0.810 rs2296590 chr10:104262628 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1799949 0.965 rs8067269 chr17:41235799 C/T cg05368731 chr17:41323189 NBR1 0.65 11.01 0.51 2.5300000000000002e-24 Menopause (age at onset); LIHC cis rs1008375 0.931 rs3796814 chr4:17602033 G/C cg02297831 chr4:17616191 MED28 0.44 6.81 0.35 4.51e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs751728 0.865 rs751726 chr6:33764386 G/A cg25922239 chr6:33757077 LEMD2 0.44 7.33 0.37 1.66e-12 Crohn's disease; LIHC cis rs35110281 0.627 rs1836855 chr21:44965414 C/G cg04455712 chr21:45112962 RRP1B 0.41 6.82 0.35 4.19e-11 Mean corpuscular volume; LIHC cis rs36051895 0.659 rs7862042 chr9:5268139 G/A cg02405213 chr9:5042618 JAK2 -0.57 -8.79 -0.43 7.22e-17 Pediatric autoimmune diseases; LIHC cis rs12971120 0.891 rs2278158 chr18:72178300 G/T cg25817165 chr18:72167213 CNDP2 -0.71 -12.24 -0.55 8.01e-29 Refractive error; LIHC cis rs589448 0.538 rs622656 chr12:69753595 C/T cg19645103 chr12:69753606 YEATS4 -0.52 -7.84 -0.39 5.89e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs17125944 0.506 rs7160285 chr14:53311400 A/C cg00686598 chr14:53173677 PSMC6 -0.79 -9.37 -0.45 9.77e-19 Alzheimer's disease (late onset); LIHC cis rs2439831 0.850 rs2439832 chr15:43779686 C/T cg15269541 chr15:43626905 ADAL -0.3 -5.91 -0.3 8.21e-9 Lung cancer in ever smokers; LIHC cis rs17685 0.753 rs4728550 chr7:75670988 C/A cg04610667 chr7:75704037 NA 0.35 6.2 0.32 1.61e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2730245 0.505 rs2657360 chr7:158673604 A/G cg23730037 chr7:158596552 ESYT2 -0.41 -6.37 -0.33 6.22e-10 Height; LIHC cis rs6860806 0.507 rs272891 chr5:131664394 G/T cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.79e-31 Breast cancer; LIHC cis rs4742903 0.935 rs1889284 chr9:106926980 C/T cg14250997 chr9:106856677 SMC2 0.36 6.14 0.32 2.27e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs950169 0.614 rs12903883 chr15:84680553 A/G cg17507749 chr15:85114479 UBE2QP1 0.69 6.52 0.33 2.57e-10 Schizophrenia; LIHC cis rs798554 0.836 rs798526 chr7:2775542 G/C cg19717773 chr7:2847554 GNA12 -0.42 -6.79 -0.34 5e-11 Height; LIHC cis rs57590327 0.527 rs11917558 chr3:81610805 G/A cg07356753 chr3:81810745 GBE1 -0.56 -8.5 -0.42 5.84e-16 Extraversion; LIHC cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg02564969 chr6:151773285 C6orf211;RMND1 0.53 8.26 0.41 3.33e-15 Menarche (age at onset); LIHC cis rs6582630 0.537 rs7299661 chr12:38527713 C/T cg26384229 chr12:38710491 ALG10B 0.63 8.98 0.44 1.8e-17 Drug-induced liver injury (flucloxacillin); LIHC cis rs8017423 0.967 rs11624725 chr14:90713609 G/T cg14092571 chr14:90743983 NA 0.39 6.2 0.32 1.61e-9 Mortality in heart failure; LIHC cis rs1055129 0.655 rs8067076 chr17:73837142 G/T cg10935138 chr17:73851978 WBP2 -0.45 -7.07 -0.36 8.78e-12 White matter hyperintensity burden; LIHC cis rs9549367 0.789 rs9549716 chr13:113908478 G/A cg18105134 chr13:113819100 PROZ -0.58 -10.29 -0.49 8.43e-22 Platelet distribution width; LIHC cis rs67460515 0.563 rs11922959 chr3:160828871 A/G cg03342759 chr3:160939853 NMD3 -0.62 -9.14 -0.44 5.77e-18 Parkinson's disease; LIHC cis rs17685 0.736 rs4732594 chr7:75753273 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2576037 0.526 rs658756 chr18:44431832 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 10.43 0.49 2.63e-22 Personality dimensions; LIHC cis rs9868809 0.772 rs9811318 chr3:48702606 A/G cg07636037 chr3:49044803 WDR6 -0.61 -7.29 -0.37 2.14e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC trans rs4820294 0.669 rs1894532 chr22:38059750 T/C cg19894588 chr14:64061835 NA -0.48 -7.58 -0.38 3.17e-13 Fat distribution (HIV); LIHC trans rs911555 0.755 rs2756135 chr14:103962579 G/A cg17675199 chr6:35436792 RPL10A -0.44 -9.11 -0.44 7.26e-18 Intelligence (multi-trait analysis); LIHC cis rs950169 0.580 rs36126054 chr15:85177723 T/G cg12863693 chr15:85201151 NMB 0.48 6.87 0.35 3.13e-11 Schizophrenia; LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg04013166 chr16:89971882 TCF25 0.6 7.9 0.39 3.72e-14 Skin colour saturation; LIHC cis rs2153535 0.601 rs9379224 chr6:8538413 A/G cg23788917 chr6:8435910 SLC35B3 0.62 8.57 0.42 3.51e-16 Motion sickness; LIHC cis rs4700695 1.000 rs4700696 chr5:65412634 G/C cg21114390 chr5:65439923 SFRS12 -0.47 -6.07 -0.31 3.36e-9 Facial morphology (factor 19); LIHC cis rs9902453 1.000 rs9891871 chr17:28370191 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.85 -0.54 2.23e-27 Coffee consumption (cups per day); LIHC cis rs2075371 0.933 rs1833474 chr7:133958240 A/G cg20476274 chr7:133979776 SLC35B4 0.75 12.92 0.57 2.25e-31 Mean platelet volume; LIHC cis rs12477438 0.765 rs7605218 chr2:99593080 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.48 -0.37 6.34e-13 Chronic sinus infection; LIHC cis rs7542091 1.000 rs7542091 chr1:210031948 G/C cg23283495 chr1:209979779 IRF6 0.37 6.18 0.32 1.81e-9 Monobrow; LIHC cis rs7584330 0.738 rs13398506 chr2:238374824 A/G cg14458575 chr2:238380390 NA 0.41 6.42 0.33 4.45e-10 Prostate cancer; LIHC trans rs7615952 0.736 rs9862893 chr3:125686974 A/G cg07211511 chr3:129823064 LOC729375 -0.51 -6.12 -0.31 2.52e-9 Blood pressure (smoking interaction); LIHC cis rs6424115 0.708 rs12755062 chr1:24185025 T/A cg15997130 chr1:24165203 NA -0.37 -6.58 -0.34 1.76e-10 Immature fraction of reticulocytes; LIHC cis rs11677370 0.561 rs10191326 chr2:3827524 G/C cg17052675 chr2:3827356 NA -0.58 -7.63 -0.38 2.4e-13 Type 2 diabetes; LIHC cis rs9326248 0.953 rs634960 chr11:117072963 T/C cg15534755 chr11:117069859 TAGLN -0.39 -6.56 -0.33 1.96e-10 Blood protein levels; LIHC cis rs7959452 0.868 rs10784774 chr12:69737879 C/T cg22834771 chr12:69754056 YEATS4 0.39 6.36 0.33 6.48e-10 Blood protein levels; LIHC cis rs2243480 0.615 rs34363376 chr7:65939536 T/C cg07424592 chr7:64974309 NA 0.8 9.05 0.44 1.12e-17 Diabetic kidney disease; LIHC cis rs1816752 0.870 rs7981337 chr13:25015053 A/C cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs4332037 0.851 rs34040190 chr7:1920356 G/A cg23422044 chr7:1970798 MAD1L1 -0.65 -7.44 -0.37 8.28e-13 Bipolar disorder; LIHC cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.15 -0.32 2.12e-9 Colorectal cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24928681 chr11:74700231 NEU3 0.45 6.16 0.32 2.06e-9 Lung function (FEV1/FVC); LIHC cis rs929354 0.713 rs6459733 chr7:156930550 G/C cg16102536 chr7:156981717 UBE3C 0.36 6.14 0.31 2.34e-9 Body mass index; LIHC cis rs7131987 0.903 rs7308125 chr12:29425211 T/C cg00204748 chr12:29376779 FAR2 0.4 7.5 0.38 5.68e-13 QT interval; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12230010 chr10:72163718 EIF4EBP2 0.39 6.09 0.31 3.1e-9 Cognitive function; LIHC cis rs35110281 0.837 rs7279958 chr21:45016016 C/A cg04455712 chr21:45112962 RRP1B 0.43 7.43 0.37 8.54e-13 Mean corpuscular volume; LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs7953508 0.659 rs1316739 chr12:93968256 G/A cg18151635 chr12:93972918 NA -0.5 -8.49 -0.42 6.24e-16 Pubertal anthropometrics; LIHC cis rs965469 0.779 rs2236119 chr20:3303576 G/T cg25506879 chr20:3388711 C20orf194 -0.5 -6.18 -0.32 1.81e-9 IFN-related cytopenia; LIHC cis rs12824058 0.831 rs12831363 chr12:130814013 C/T cg24229701 chr12:130821962 PIWIL1 -0.44 -6.77 -0.34 5.55e-11 Menopause (age at onset); LIHC cis rs796364 1.000 rs1658807 chr2:200767512 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.77 8.89 0.43 3.68e-17 Schizophrenia; LIHC cis rs61861422 0.516 rs12412216 chr10:134393338 C/T cg18305652 chr10:134549665 INPP5A 0.4 6.15 0.32 2.22e-9 Primary sclerosing cholangitis; LIHC cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg18404041 chr3:52824283 ITIH1 -0.41 -6.73 -0.34 7.3e-11 Electroencephalogram traits; LIHC cis rs6089584 0.893 rs6089306 chr20:60574868 G/A cg12751644 chr20:60527061 NA -0.36 -6.08 -0.31 3.3e-9 Body mass index; LIHC cis rs35306767 0.715 rs11253550 chr10:1028288 C/G cg20503657 chr10:835505 NA 0.84 7.52 0.38 4.8e-13 Eosinophil percentage of granulocytes; LIHC cis rs7927592 0.871 rs17603185 chr11:68376241 C/T cg20283391 chr11:68216788 NA -0.52 -7.7 -0.38 1.43e-13 Total body bone mineral density; LIHC cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg17971929 chr21:40555470 PSMG1 -0.39 -6.01 -0.31 4.64e-9 Menarche (age at onset); LIHC cis rs7107174 1.000 rs2510051 chr11:77981171 A/C cg02023728 chr11:77925099 USP35 0.49 9.58 0.46 2.09e-19 Testicular germ cell tumor; LIHC cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg00149659 chr3:10157352 C3orf10 0.69 6.99 0.35 1.49e-11 Alzheimer's disease; LIHC cis rs244293 0.795 rs12940239 chr17:53068930 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.46 -6.54 -0.33 2.24e-10 Menarche (age at onset); LIHC trans rs12478296 0.786 rs13409307 chr2:242995499 G/C cg01596870 chr19:55963115 NA -0.65 -9.51 -0.46 3.47e-19 Obesity-related traits; LIHC cis rs4319547 0.585 rs7953007 chr12:122816977 A/C cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.27 -0.37 2.46e-12 Body mass index; LIHC cis rs2191566 0.960 rs11083733 chr19:44520919 G/C cg20607764 chr19:44506953 ZNF230 -0.41 -6.7 -0.34 8.82e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg18252515 chr7:66147081 NA -1.3 -16.62 -0.67 6.84e-46 Diabetic kidney disease; LIHC trans rs2243480 0.708 rs35825036 chr7:65986502 T/C cg10756647 chr7:56101905 PSPH 1.02 12.11 0.55 2.53e-28 Diabetic kidney disease; LIHC cis rs2974760 0.606 rs2858918 chr16:201183 T/C cg08400316 chr16:204221 HBZ 0.77 13.03 0.58 8.32e-32 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.35 0.8 1.14e-76 Prudent dietary pattern; LIHC cis rs8177179 0.967 rs10935085 chr3:133459735 C/T cg24879335 chr3:133465180 TF 0.46 10.68 0.5 3.48e-23 Iron status biomarkers (transferrin levels); LIHC cis rs870825 0.616 rs6834156 chr4:185639903 G/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg06634786 chr22:41940651 POLR3H 0.73 7.59 0.38 3.04e-13 Vitiligo; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11955762 chr13:111268705 CARKD 0.5 6.34 0.32 7.22e-10 Lung function (FEV1/FVC); LIHC cis rs2629540 0.889 rs4962402 chr10:126459114 T/G cg08799069 chr10:126477246 METTL10 -0.53 -8.59 -0.42 3.15e-16 Cocaine dependence; LIHC cis rs6912958 0.712 rs2307379 chr6:88366771 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.62 -0.38 2.47e-13 Monocyte percentage of white cells; LIHC cis rs56146971 0.714 rs79810056 chr14:91852929 A/G cg16433844 chr14:91963127 SMEK1 -0.52 -6.18 -0.32 1.87e-9 Alzheimer disease and age of onset; LIHC cis rs9790314 1.000 rs336583 chr3:161081981 A/T cg03342759 chr3:160939853 NMD3 0.7 8.33 0.41 2.02e-15 Morning vs. evening chronotype; LIHC cis rs7572733 0.515 rs1518368 chr2:198839145 G/A cg10820045 chr2:198174542 NA 0.46 6.99 0.35 1.48e-11 Dermatomyositis; LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg19635926 chr16:89946313 TCF25 0.56 7.58 0.38 3.24e-13 Skin colour saturation; LIHC cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg05564831 chr3:52568323 NT5DC2 0.37 6.03 0.31 4.19e-9 Bipolar disorder; LIHC trans rs1814175 0.817 rs28544182 chr11:50049577 G/T cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs929354 0.772 rs2301916 chr7:156974127 G/T cg05182265 chr7:156933206 UBE3C -0.32 -6.06 -0.31 3.66e-9 Body mass index; LIHC cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg07424592 chr7:64974309 NA -0.8 -9.23 -0.45 2.94e-18 Diabetic kidney disease; LIHC cis rs372883 0.648 rs15092 chr21:30718201 G/A cg08807101 chr21:30365312 RNF160 -0.51 -5.9 -0.3 8.83e-9 Pancreatic cancer; LIHC cis rs765787 0.530 rs4775837 chr15:45537684 G/T cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs7927592 0.763 rs4340059 chr11:68362433 A/G cg20283391 chr11:68216788 NA -0.38 -6.08 -0.31 3.14e-9 Total body bone mineral density; LIHC cis rs644799 0.544 rs1727165 chr11:95521648 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.64 9.36 0.45 1.06e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9467773 1.000 rs6930120 chr6:26555484 A/G cg11502198 chr6:26597334 ABT1 0.45 6.57 0.33 1.85e-10 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg07061783 chr6:25882402 NA 0.64 8.22 0.41 4.25e-15 Blood metabolite levels; LIHC cis rs4474465 0.790 rs12363982 chr11:78229167 C/T cg27205649 chr11:78285834 NARS2 0.38 5.82 0.3 1.32e-8 Alzheimer's disease (survival time); LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg09455208 chr3:40491958 NA 0.37 7.35 0.37 1.48e-12 Renal cell carcinoma; LIHC cis rs832187 0.704 rs704364 chr3:63874734 A/G cg16258503 chr3:63850278 ATXN7;THOC7 0.45 6.29 0.32 9.65e-10 Schizophrenia; LIHC cis rs7552404 0.924 rs67757078 chr1:76169456 G/A cg22875332 chr1:76189707 ACADM 0.48 7.53 0.38 4.52e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC cis rs6694270 0.529 rs11261065 chr1:19106254 A/C cg26220594 chr1:19110978 NA -0.35 -6.0 -0.31 5.15e-9 Drug-induced liver injury (nitrofurantoin); LIHC cis rs1348850 0.918 rs12463893 chr2:178448559 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.75 11.16 0.52 7.19e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg12292205 chr6:26970375 C6orf41 -0.47 -8.12 -0.4 8.73e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs7223966 1.000 rs7223672 chr17:61720565 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.65 0.34 1.15e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3741404 0.825 rs2515241 chr11:63975331 C/T cg18225595 chr11:63971243 STIP1 0.66 10.76 0.5 1.88e-23 Platelet count; LIHC cis rs2153535 0.504 rs5001323 chr6:8451605 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.42 0.41 1.07e-15 Motion sickness; LIHC cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg06238570 chr21:40685208 BRWD1 0.49 8.07 0.4 1.23e-14 Cognitive function; LIHC cis rs523522 0.962 rs509445 chr12:121017243 A/C cg27279351 chr12:120934652 DYNLL1 0.67 11.86 0.54 2.04e-27 High light scatter reticulocyte count; LIHC cis rs12928939 0.769 rs1056303 chr16:71670066 C/T cg03805757 chr16:71968109 PKD1L3 -0.56 -6.43 -0.33 4.33e-10 Post bronchodilator FEV1; LIHC cis rs826838 1.000 rs826889 chr12:39101076 G/A cg13010199 chr12:38710504 ALG10B -0.4 -5.87 -0.3 1.04e-8 Heart rate; LIHC cis rs796364 0.806 rs11674293 chr2:201026743 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -8.23 -0.41 3.99e-15 Schizophrenia; LIHC cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg23978390 chr7:1156363 C7orf50 0.61 9.28 0.45 1.97e-18 Longevity;Endometriosis; LIHC trans rs7618501 0.722 rs9853458 chr3:49783211 A/C cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC cis rs801193 1.000 rs11773829 chr7:66141074 G/A cg00343986 chr7:65444356 GUSB -0.4 -5.9 -0.3 8.7e-9 Aortic root size; LIHC cis rs4716602 0.596 rs10266659 chr7:156159278 A/G cg16983916 chr7:156159713 NA -0.32 -5.77 -0.3 1.82e-8 Anti-saccade response; LIHC cis rs5015933 0.902 rs13291306 chr9:128124798 A/T cg14078157 chr9:128172775 NA -0.39 -6.51 -0.33 2.7e-10 Body mass index; LIHC cis rs2439831 0.850 rs12101756 chr15:44053887 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.5 0.42 6.09e-16 Lung cancer in ever smokers; LIHC cis rs611744 0.967 rs662714 chr8:109221659 C/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.19e-10 Dupuytren's disease; LIHC cis rs6500602 0.727 rs2058811 chr16:4575162 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.52 0.38 4.81e-13 Schizophrenia; LIHC cis rs10256972 0.647 rs10233430 chr7:1051664 T/C cg23978390 chr7:1156363 C7orf50 0.42 6.17 0.32 1.93e-9 Longevity;Endometriosis; LIHC cis rs9633740 1.000 rs9633740 chr10:82265271 A/G cg01528321 chr10:82214614 TSPAN14 0.94 11.51 0.53 3.93e-26 Post bronchodilator FEV1; LIHC cis rs6456156 0.586 rs10946209 chr6:167480991 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.64 -0.42 2.18e-16 Primary biliary cholangitis; LIHC cis rs11098499 0.909 rs11723757 chr4:120299669 C/T cg09307838 chr4:120376055 NA 0.76 11.74 0.54 5.79e-27 Corneal astigmatism; LIHC cis rs2257205 0.667 rs16943200 chr17:56829611 A/G cg12560992 chr17:57184187 TRIM37 0.71 7.78 0.39 8.76e-14 Pancreatic cancer; LIHC cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg01017244 chr2:74357527 NA 0.63 11.29 0.52 2.36e-25 Gestational age at birth (maternal effect); LIHC cis rs4820294 0.669 rs35662099 chr22:38053909 C/T cg10587741 chr22:38071170 LGALS1 0.45 8.05 0.4 1.42e-14 Fat distribution (HIV); LIHC cis rs9527 0.637 rs12219247 chr10:104613361 A/G cg11784071 chr10:104629166 AS3MT -0.35 -5.82 -0.3 1.32e-8 Arsenic metabolism; LIHC cis rs722599 0.501 rs2286912 chr14:75385437 C/T cg11812906 chr14:75593930 NEK9 -0.46 -7.58 -0.38 3.37e-13 IgG glycosylation; LIHC cis rs826838 0.616 rs11182893 chr12:38627715 C/G cg26384229 chr12:38710491 ALG10B -0.51 -7.12 -0.36 6.56e-12 Heart rate; LIHC cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg00149659 chr3:10157352 C3orf10 0.69 7.28 0.37 2.3e-12 Alzheimer's disease; LIHC cis rs4727027 0.704 rs12535115 chr7:148895087 C/T cg23583168 chr7:148888333 NA -0.77 -11.75 -0.54 5.24e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs875971 0.660 rs3857686 chr7:66036191 C/T cg14393609 chr7:65229607 NA -0.37 -5.81 -0.3 1.4e-8 Aortic root size; LIHC cis rs6089584 0.927 rs2296083 chr20:60574216 C/T cg12751644 chr20:60527061 NA -0.36 -6.08 -0.31 3.3e-9 Body mass index; LIHC cis rs8084351 0.577 rs8083719 chr18:50638557 A/G cg24270629 chr18:50823537 DCC 0.43 6.38 0.33 5.78e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs929354 0.713 rs6946947 chr7:156948787 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.36 0.45 1.11e-18 Bipolar disorder; LIHC cis rs9916302 0.851 rs11657899 chr17:37626963 G/A cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC cis rs1552244 0.882 rs7636817 chr3:10014876 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.47 -0.49 1.92e-22 Alzheimer's disease; LIHC cis rs9896052 0.614 rs6501800 chr17:73446891 A/T cg25649188 chr17:73499917 CASKIN2 -0.45 -6.83 -0.35 3.99e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs10876993 0.855 rs1689604 chr12:58048304 T/C cg18357645 chr12:58087776 OS9 0.53 8.58 0.42 3.26e-16 Celiac disease or Rheumatoid arthritis; LIHC trans rs2243480 0.803 rs34804747 chr7:65412942 G/C cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs2991971 0.810 rs12738318 chr1:45929589 A/G cg05343316 chr1:45956843 TESK2 0.45 6.42 0.33 4.68e-10 High light scatter reticulocyte count; LIHC cis rs6597981 0.675 rs4963120 chr11:825777 A/G cg21775979 chr11:780331 NA 0.44 7.0 0.35 1.38e-11 Breast cancer; LIHC cis rs6748734 0.817 rs10182575 chr2:241806690 C/T cg04034577 chr2:241836375 C2orf54 -0.44 -9.89 -0.47 1.8899999999999998e-20 Urinary metabolites; LIHC cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg22907277 chr7:1156413 C7orf50 0.55 8.3 0.41 2.42e-15 Longevity;Endometriosis; LIHC cis rs600806 0.850 rs4970729 chr1:109979202 G/A cg16275483 chr1:110013120 SYPL2 -0.49 -6.05 -0.31 3.85e-9 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.808 rs2246697 chr21:46689999 G/A cg22633049 chr21:46681294 NA -0.38 -6.41 -0.33 4.75e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4555082 0.830 rs2816614 chr14:105727359 C/T cg06808227 chr14:105710500 BRF1 -0.55 -7.21 -0.36 3.58e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg13409248 chr3:40428643 ENTPD3 0.43 7.08 0.36 8.19e-12 Renal cell carcinoma; LIHC cis rs4903214 0.895 rs10130040 chr14:74713682 A/C cg11132536 chr14:74711944 VSX2 -0.24 -6.22 -0.32 1.45e-9 Inflammatory bowel disease; LIHC cis rs1023500 1.000 rs7293091 chr22:42341308 A/G cg04733989 chr22:42467013 NAGA -0.49 -5.82 -0.3 1.32e-8 Schizophrenia; LIHC cis rs7238033 0.624 rs8090908 chr18:43310187 A/G cg20610511 chr18:43302872 SLC14A1 0.39 6.46 0.33 3.55e-10 Bladder cancer; LIHC cis rs5769765 0.908 rs9616388 chr22:50313438 T/C cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg04013166 chr16:89971882 TCF25 0.61 7.97 0.4 2.38e-14 Skin colour saturation; LIHC cis rs929354 0.742 rs6459734 chr7:156935454 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs780096 0.587 rs6760828 chr2:27579231 T/C cg22903471 chr2:27725779 GCKR -0.51 -8.93 -0.43 2.68e-17 Total body bone mineral density; LIHC cis rs798554 1.000 rs798540 chr7:2764130 G/A cg19346786 chr7:2764209 NA -0.46 -6.97 -0.35 1.67e-11 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00128877 chr1:47070178 MKNK1 0.4 6.38 0.33 5.71e-10 Cognitive function; LIHC cis rs6754311 0.597 rs2082729 chr2:136550109 C/T cg07169764 chr2:136633963 MCM6 -0.69 -10.04 -0.48 5.77e-21 Mosquito bite size; LIHC cis rs12479064 0.724 rs3792150 chr2:100041849 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.65 -8.15 -0.4 7.09e-15 Chronic sinus infection; LIHC cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg02290350 chr8:58132656 NA 0.41 8.59 0.42 3.16e-16 Developmental language disorder (linguistic errors); LIHC cis rs7707921 1.000 rs749401 chr5:81561369 T/C cg15871215 chr5:81402204 ATG10 -0.59 -5.85 -0.3 1.16e-8 Breast cancer; LIHC cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg05590025 chr7:65112418 INTS4L2 0.61 6.69 0.34 9.35e-11 Diabetic kidney disease; LIHC cis rs6450176 0.564 rs401449 chr5:53326735 A/G ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.41 -0.59 3.03e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs5769707 0.967 rs1018812 chr22:50010073 C/T cg07959070 chr22:50026188 C22orf34 -0.32 -8.39 -0.41 1.3e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2404602 0.647 rs34103231 chr15:76912690 A/G cg03037974 chr15:76606532 NA -0.6 -9.92 -0.47 1.52e-20 Blood metabolite levels; LIHC cis rs11190604 0.697 rs12355942 chr10:102201320 T/C cg07080220 chr10:102295463 HIF1AN -0.47 -6.79 -0.34 5.07e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs908922 0.676 rs10888491 chr1:152492622 A/G cg23254163 chr1:152506842 NA 0.22 5.74 0.3 2.06e-8 Hair morphology; LIHC cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg22907277 chr7:1156413 C7orf50 0.74 5.89 0.3 9.4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs870825 0.616 rs7667409 chr4:185650941 C/T cg04058563 chr4:185651563 MLF1IP -0.63 -6.82 -0.35 4.1e-11 Blood protein levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00259882 chr11:70049130 FADD 0.57 7.59 0.38 3.06e-13 Lung function (FEV1/FVC); LIHC cis rs72945132 0.882 rs59681006 chr11:70179401 T/C cg00319359 chr11:70116639 PPFIA1 0.63 5.74 0.3 2.1e-8 Coronary artery disease; LIHC cis rs9457247 0.967 rs428805 chr6:167403132 C/A cg23791538 chr6:167370224 RNASET2 -0.65 -11.04 -0.51 1.98e-24 Crohn's disease; LIHC cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg02931644 chr1:25747376 RHCE 0.35 7.43 0.37 9e-13 Plateletcrit;Mean corpuscular volume; LIHC cis rs10883723 0.668 rs12414479 chr10:104420902 C/T cg22532475 chr10:104410764 TRIM8 -0.38 -6.18 -0.32 1.82e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs9980664 1.000 rs9978964 chr21:34736952 T/C cg04842828 chr21:34696676 IFNAR1 0.46 6.15 0.32 2.21e-9 Cognitive decline (age-related); LIHC cis rs13108904 0.517 rs4974551 chr4:1336410 C/A cg13395646 chr4:1353034 KIAA1530 -0.82 -12.52 -0.56 7.22e-30 Obesity-related traits; LIHC cis rs9916302 0.904 rs8079560 chr17:37497661 C/T cg00129232 chr17:37814104 STARD3 0.38 6.08 0.31 3.27e-9 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.26 0.8 2.39e-76 Prudent dietary pattern; LIHC trans rs208520 1.000 rs9453663 chr6:66976077 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 6.91 0.35 2.35e-11 Exhaled nitric oxide output; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02576938 chr4:89442616 PIGY 0.37 6.23 0.32 1.36e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6964587 1.000 rs2237568 chr7:91622676 G/A cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs12971120 0.947 rs3764509 chr18:72167124 C/G cg25817165 chr18:72167213 CNDP2 -0.68 -12.67 -0.57 1.96e-30 Refractive error; LIHC cis rs9790314 0.967 rs9821201 chr3:160996155 G/C cg04691961 chr3:161091175 C3orf57 -0.39 -6.1 -0.31 2.91e-9 Morning vs. evening chronotype; LIHC cis rs7833790 0.724 rs4739627 chr8:82734657 A/G cg02079420 chr8:82753780 SNX16 0.37 6.8 0.34 4.77e-11 Diastolic blood pressure; LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg00656387 chr3:40428638 ENTPD3 -0.49 -8.03 -0.4 1.62e-14 Renal cell carcinoma; LIHC cis rs748404 0.578 rs478028 chr15:43610772 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.58 9.23 0.45 2.9e-18 Lung cancer; LIHC cis rs16854884 0.657 rs2099543 chr3:143742164 C/T cg06585982 chr3:143692056 C3orf58 0.55 7.21 0.36 3.58e-12 Economic and political preferences (feminism/equality); LIHC cis rs7208859 0.673 rs9898858 chr17:29156211 A/T cg13385521 chr17:29058706 SUZ12P 0.82 7.99 0.4 2.16e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3806843 1.000 rs10073974 chr5:140165231 T/C cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC trans rs1814175 0.817 rs28594987 chr11:50045181 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.41e-11 Height; LIHC cis rs6076065 0.707 rs12349 chr20:23352480 A/G cg11657817 chr20:23433608 CST11 0.33 6.99 0.35 1.44e-11 Facial morphology (factor 15, philtrum width); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15243024 chr2:27651571 NRBP1 -0.52 -6.41 -0.33 4.94e-10 Systolic blood pressure; LIHC cis rs77633900 0.614 rs280001 chr15:77003566 C/A cg21673338 chr15:77095150 SCAPER -0.5 -7.46 -0.37 6.99e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs2404602 0.692 rs67570291 chr15:77020502 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.9 0.3 8.97e-9 Blood metabolite levels; LIHC cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs6963495 0.818 rs17343556 chr7:105151272 C/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs11583043 0.918 rs6577216 chr1:101409972 C/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.48 0.46 4.35e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1538970 0.847 rs1771550 chr1:45883565 C/T cg15605315 chr1:45957053 TESK2 0.44 5.93 0.31 7.27e-9 Platelet count; LIHC cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg10295955 chr4:187884368 NA -0.97 -21.9 -0.76 4.6e-67 Lobe attachment (rater-scored or self-reported); LIHC trans rs1499614 0.803 rs1922723 chr7:66175063 C/T cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs35146811 0.807 rs6465761 chr7:99620277 G/C cg13334819 chr7:99746414 C7orf59 -0.55 -7.88 -0.39 4.38e-14 Coronary artery disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07590584 chr13:113140145 TUBGCP3 0.39 6.32 0.32 8.19e-10 Longevity; LIHC cis rs61440199 0.818 rs11128940 chr3:20159199 G/A cg00235661 chr3:20228976 SGOL1 -0.44 -6.25 -0.32 1.2e-9 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs72781680 0.898 rs113522526 chr2:24018476 C/T cg08917208 chr2:24149416 ATAD2B 0.84 7.55 0.38 3.93e-13 Lymphocyte counts; LIHC cis rs920590 0.573 rs6986456 chr8:19680562 A/G cg03894339 chr8:19674705 INTS10 0.46 6.91 0.35 2.45e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs10924970 0.934 rs2891026 chr1:235429907 A/C cg26050004 chr1:235667680 B3GALNT2 0.4 5.86 0.3 1.07e-8 Asthma; LIHC cis rs7903847 0.619 rs10882912 chr10:99138077 C/T cg20016023 chr10:99160130 RRP12 -0.42 -6.51 -0.33 2.65e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1552244 0.554 rs4488814 chr3:10002400 C/T cg02579736 chr3:10068473 FANCD2;CIDECP -0.55 -7.77 -0.39 8.98e-14 Alzheimer's disease; LIHC cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg11890956 chr21:40555474 PSMG1 1.05 15.08 0.63 9.62e-40 Cognitive function; LIHC cis rs17685 0.753 rs4728586 chr7:75802869 T/C cg16684958 chr7:75615977 POR 0.52 8.57 0.42 3.5e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67460515 0.892 rs11711695 chr3:161057593 A/G cg17135325 chr3:160939158 NMD3 0.56 8.24 0.41 3.62e-15 Parkinson's disease; LIHC cis rs57590327 0.503 rs1524557 chr3:81892031 A/G cg07356753 chr3:81810745 GBE1 -0.5 -7.72 -0.39 1.3e-13 Extraversion; LIHC cis rs3008870 1.000 rs2815352 chr1:67482104 A/G cg02640540 chr1:67518911 SLC35D1 0.44 6.01 0.31 4.67e-9 Lymphocyte percentage of white cells; LIHC cis rs7208859 0.623 rs9897728 chr17:29108804 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs11088226 0.681 rs2833899 chr21:33933263 T/C cg09050820 chr6:167586206 TCP10L2 0.87 13.71 0.6 2.19e-34 Gastritis; LIHC cis rs4409675 0.576 rs7356 chr1:28218100 T/C cg23691781 chr1:28212827 C1orf38 0.32 7.76 0.39 9.61e-14 Corneal astigmatism; LIHC cis rs10751667 0.666 rs7943140 chr11:973824 T/C cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.53e-13 Alzheimer's disease (late onset); LIHC cis rs12477438 0.765 rs10181344 chr2:99692829 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.37 -0.41 1.51e-15 Chronic sinus infection; LIHC cis rs11112613 0.713 rs11112587 chr12:105941285 G/A cg03607813 chr12:105948248 NA 0.65 12.52 0.56 7.19e-30 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg18876405 chr7:65276391 NA 0.56 9.42 0.45 6.71e-19 Aortic root size; LIHC cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg25894440 chr7:65020034 NA 0.52 6.02 0.31 4.45e-9 Diabetic kidney disease; LIHC cis rs8027181 0.606 rs12911743 chr15:73104935 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.43 6.56 0.33 1.98e-10 Triglyceride levels; LIHC cis rs11671005 0.735 rs11881000 chr19:58932788 C/T cg25952890 chr19:58913133 NA 0.67 7.2 0.36 3.89e-12 Mean platelet volume; LIHC cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg06238570 chr21:40685208 BRWD1 -0.51 -8.4 -0.41 1.21e-15 Cognitive function; LIHC cis rs10751667 0.666 rs4074234 chr11:977715 C/G cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs7769051 1.000 rs6934161 chr6:133124077 C/T cg22852734 chr6:133119734 C6orf192 -0.98 -9.79 -0.47 4.07e-20 Type 2 diabetes nephropathy; LIHC cis rs7914558 0.902 rs7092200 chr10:104844872 T/C cg15744005 chr10:104629667 AS3MT -0.37 -8.36 -0.41 1.6e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg24549020 chr5:56110836 MAP3K1 0.52 6.4 0.33 5.23e-10 Initial pursuit acceleration; LIHC cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC cis rs11167764 1.000 rs7730511 chr5:141480418 T/C cg23435118 chr5:141488016 NDFIP1 -0.44 -6.12 -0.31 2.61e-9 Crohn's disease; LIHC cis rs3770081 1.000 rs12621992 chr2:86345349 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -7.9 -0.39 3.9e-14 Facial emotion recognition (sad faces); LIHC cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg05890377 chr2:74357713 NA 0.63 12.64 0.56 2.58e-30 Gestational age at birth (maternal effect); LIHC cis rs709400 1.000 rs3783404 chr14:104118498 A/G cg26031613 chr14:104095156 KLC1 1.06 14.27 0.61 1.38e-36 Body mass index; LIHC cis rs9486719 0.895 rs12190520 chr6:96928620 A/C cg06623918 chr6:96969491 KIAA0776 -0.66 -6.7 -0.34 8.45e-11 Migraine;Coronary artery disease; LIHC cis rs1707322 1.000 rs4298677 chr1:46306619 G/A cg03146154 chr1:46216737 IPP 0.47 7.57 0.38 3.52e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.56 -10.3 -0.49 7.31e-22 Total body bone mineral density; LIHC cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg10295955 chr4:187884368 NA -0.98 -22.24 -0.77 2.11e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs79149102 0.579 rs61166993 chr15:75306644 C/A cg17294928 chr15:75287854 SCAMP5 -0.48 -6.35 -0.32 7e-10 Lung cancer; LIHC cis rs3020736 0.500 rs6002623 chr22:42513761 G/A cg04733989 chr22:42467013 NAGA -0.64 -9.18 -0.44 4.09e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs9503598 0.502 rs4959833 chr6:3435114 T/A cg00476032 chr6:3446245 SLC22A23 -0.32 -5.89 -0.3 9.42e-9 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs763121 0.853 rs1569716 chr22:38998519 C/A cg06022373 chr22:39101656 GTPBP1 0.75 15.06 0.63 1.09e-39 Menopause (age at onset); LIHC cis rs8083850 0.603 rs11665094 chr18:50852319 A/G cg24270629 chr18:50823537 DCC 0.53 7.97 0.4 2.39e-14 Intelligence (multi-trait analysis); LIHC cis rs7178375 1.000 rs9806159 chr15:31209654 G/T cg19680485 chr15:31195859 MTMR15 -0.5 -5.79 -0.3 1.61e-8 Hypertriglyceridemia; LIHC cis rs763014 0.966 rs35642938 chr16:642249 T/C cg09263875 chr16:632152 PIGQ 0.55 9.87 0.47 2.17e-20 Height; LIHC cis rs6570726 0.791 rs12208019 chr6:145935572 T/C cg23711669 chr6:146136114 FBXO30 0.74 12.47 0.56 1.14e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs317689 0.613 rs315112 chr12:69785926 T/A cg20891283 chr12:69753455 YEATS4 0.82 15.96 0.65 3.14e-43 Response to diuretic therapy; LIHC cis rs782590 0.935 rs782649 chr2:55860308 T/C cg03859395 chr2:55845619 SMEK2 0.92 16.37 0.66 6.68e-45 Metabolic syndrome; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24504843 chr4:56896641 CEP135 0.47 7.08 0.36 8.48e-12 Longevity; LIHC cis rs2637030 0.586 rs12521381 chr5:52846195 C/T cg06476337 chr5:52856530 NDUFS4 0.38 6.31 0.32 8.8e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs992157 0.835 rs13005100 chr2:219151767 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.78 -12.48 -0.56 9.93e-30 Colorectal cancer; LIHC cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg06238570 chr21:40685208 BRWD1 0.56 6.79 0.34 4.99e-11 Cognitive function; LIHC cis rs1385374 0.858 rs10847697 chr12:129299385 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.59 7.47 0.37 6.75e-13 Systemic lupus erythematosus; LIHC cis rs11758351 0.789 rs2069020 chr6:26205500 C/T cg11342453 chr6:26196699 NA 0.52 5.8 0.3 1.55e-8 Gout;Renal underexcretion gout; LIHC cis rs763121 0.853 rs9610993 chr22:39042818 C/A cg06022373 chr22:39101656 GTPBP1 0.67 11.75 0.54 5.21e-27 Menopause (age at onset); LIHC cis rs2963155 0.518 rs712189 chr5:142631258 C/T cg17617527 chr5:142782415 NR3C1 0.96 10.38 0.49 4.04e-22 Breast cancer; LIHC cis rs67478160 0.643 rs876002 chr14:104239697 G/A cg08213375 chr14:104286397 PPP1R13B 0.66 13.06 0.58 6.68e-32 Schizophrenia; LIHC trans rs61931739 0.500 rs34061369 chr12:34519283 C/T cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg26831259 chr4:1366826 KIAA1530 -0.37 -5.84 -0.3 1.22e-8 Longevity; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg06656553 chr16:89960601 TCF25 -0.46 -5.86 -0.3 1.08e-8 Skin colour saturation; LIHC cis rs826838 0.935 rs11169508 chr12:39173385 C/T cg13010199 chr12:38710504 ALG10B 0.51 6.21 0.32 1.55e-9 Heart rate; LIHC cis rs12744310 0.887 rs12026404 chr1:41801912 C/A cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2576037 0.526 rs998819 chr18:44564181 C/T cg19077165 chr18:44547161 KATNAL2 0.45 6.93 0.35 2.04e-11 Personality dimensions; LIHC cis rs9527 0.551 rs28606370 chr10:104670832 C/A cg15744005 chr10:104629667 AS3MT -0.42 -9.42 -0.45 7.17e-19 Arsenic metabolism; LIHC cis rs2717559 0.522 rs10956987 chr8:143886613 T/C cg07661805 chr8:143867942 LY6D -0.27 -5.91 -0.3 8.48e-9 Urinary tract infection frequency; LIHC cis rs12286929 0.839 rs12790574 chr11:115009145 C/T cg04055981 chr11:115044050 NA 0.4 5.84 0.3 1.19e-8 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7904368 0.754 rs12253908 chr10:16853358 T/C cg23933602 chr10:16859644 RSU1 0.6 5.79 0.3 1.58e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs6430585 0.528 rs7606267 chr2:136668123 T/C cg25344623 chr2:136566232 LCT -0.38 -6.18 -0.32 1.78e-9 Corneal structure; LIHC cis rs67478160 0.704 rs12894254 chr14:104290949 G/C cg08213375 chr14:104286397 PPP1R13B 0.65 12.6 0.56 3.75e-30 Schizophrenia; LIHC cis rs35306767 0.903 rs11253462 chr10:889323 T/G cg20503657 chr10:835505 NA 1.02 12.21 0.55 1.02e-28 Eosinophil percentage of granulocytes; LIHC cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC trans rs7668874 0.779 rs7698241 chr4:116805566 C/T cg08917878 chr5:172668965 NA -0.31 -6.07 -0.31 3.45e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs2976388 1.000 rs2572910 chr8:143770135 C/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.81 -0.3 1.39e-8 Urinary tract infection frequency; LIHC cis rs35306767 0.714 rs12762955 chr10:1078782 A/C cg26597838 chr10:835615 NA 0.63 6.9 0.35 2.49e-11 Eosinophil percentage of granulocytes; LIHC cis rs992157 0.764 rs4672886 chr2:219185545 C/T cg00012203 chr2:219082015 ARPC2 -0.76 -10.83 -0.51 1.08e-23 Colorectal cancer; LIHC cis rs3008870 0.958 rs12143044 chr1:67460054 A/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs2439831 1.000 rs565007 chr15:43716641 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.66 0.59 3.34e-34 Lung cancer in ever smokers; LIHC trans rs11165623 0.564 rs7555035 chr1:96996026 T/C cg10631902 chr5:14652156 NA -0.3 -6.84 -0.35 3.59e-11 Hip circumference;Waist circumference; LIHC cis rs2836950 0.565 rs2836942 chr21:40591381 A/G cg06238570 chr21:40685208 BRWD1 -0.43 -7.01 -0.35 1.29e-11 Menarche (age at onset); LIHC cis rs6597981 0.592 rs10902218 chr11:743813 C/T cg01741372 chr11:783889 NA -0.67 -11.26 -0.52 3.03e-25 Breast cancer; LIHC cis rs7618915 0.781 rs12489732 chr3:52566820 C/A cg10802521 chr3:52805072 NEK4 -0.37 -5.96 -0.31 6.25e-9 Bipolar disorder; LIHC cis rs782590 0.967 rs1823893 chr2:55788921 T/C cg18811423 chr2:55921094 PNPT1 0.94 15.5 0.64 1.98e-41 Metabolic syndrome; LIHC cis rs1008375 1.000 rs55939327 chr4:17642937 T/A cg16339924 chr4:17578868 LAP3 0.44 6.19 0.32 1.68e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2953174 0.507 rs4234123 chr2:241541640 C/T cg07929629 chr2:241523174 NA 0.6 8.23 0.41 3.9e-15 Bipolar disorder; LIHC cis rs1008375 1.000 rs28552744 chr4:17620165 A/G cg16339924 chr4:17578868 LAP3 0.43 5.99 0.31 5.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.82 0.39 6.61e-14 Height; LIHC cis rs9911578 1.000 rs10401050 chr17:56953786 A/C cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg23758822 chr17:41437982 NA 0.91 16.88 0.67 6.34e-47 Menopause (age at onset); LIHC cis rs12824058 0.831 rs4759450 chr12:130812732 G/A cg24838063 chr12:130822603 PIWIL1 0.67 9.86 0.47 2.31e-20 Menopause (age at onset); LIHC cis rs2228479 0.850 rs1800339 chr16:89839637 C/A cg06558623 chr16:89946397 TCF25 0.84 11.66 0.53 1.09e-26 Skin colour saturation; LIHC cis rs3806843 0.735 rs2530240 chr5:140060547 T/C cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.32e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg15691649 chr6:25882328 NA -0.63 -8.08 -0.4 1.13e-14 Intelligence (multi-trait analysis); LIHC cis rs7089973 0.584 rs758585 chr10:116582560 C/A cg03647239 chr10:116582469 FAM160B1 0.46 6.75 0.34 6.19e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Bipolar disorder; LIHC cis rs8067354 0.645 rs2132715 chr17:57858374 A/T cg13753209 chr17:57696993 CLTC 0.76 12.01 0.54 5.85e-28 Hemoglobin concentration; LIHC cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg26831259 chr4:1366826 KIAA1530 -0.35 -5.84 -0.3 1.25e-8 Obesity-related traits; LIHC cis rs2797685 1.000 rs697691 chr1:7885354 A/G cg04725166 chr1:7887271 PER3 -0.4 -7.05 -0.36 9.69e-12 Crohn's disease; LIHC cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg05564831 chr3:52568323 NT5DC2 0.36 5.89 0.3 9.25e-9 Bipolar disorder; LIHC cis rs2832191 0.967 rs2898160 chr21:30487496 A/G cg24692254 chr21:30365293 RNF160 -0.64 -11.4 -0.52 9.9e-26 Dental caries; LIHC cis rs6933660 0.512 rs13198669 chr6:151799924 A/G cg02564969 chr6:151773285 C6orf211;RMND1 -0.45 -5.9 -0.3 8.54e-9 Menarche (age at onset); LIHC trans rs3960554 0.808 rs2302434 chr7:75630183 C/T cg19862616 chr7:65841803 NCRNA00174 0.57 7.81 0.39 7.31e-14 Eotaxin levels; LIHC cis rs9596863 0.898 rs68039282 chr13:54389435 C/A ch.13.53330881F chr13:54432880 NA 0.43 5.73 0.3 2.21e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs4727027 0.866 rs2373438 chr7:148780287 C/A cg23583168 chr7:148888333 NA -0.67 -9.44 -0.45 5.94e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6570726 1.000 rs374464 chr6:145846679 A/C cg23711669 chr6:146136114 FBXO30 0.54 9.77 0.47 4.95e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs733592 0.507 rs56129148 chr12:48485530 T/C cg21466736 chr12:48725269 NA 0.34 6.0 0.31 5.02e-9 Plateletcrit; LIHC cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg23978390 chr7:1156363 C7orf50 0.62 9.57 0.46 2.26e-19 Longevity;Endometriosis; LIHC trans rs916888 0.647 rs199524 chr17:44848438 G/T cg22968622 chr17:43663579 NA -0.48 -6.94 -0.35 1.93e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4819052 0.851 rs35560973 chr21:46662573 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.59 0.5 7.41e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12887734 0.524 rs12588797 chr14:104300020 C/T cg08213375 chr14:104286397 PPP1R13B -0.52 -9.16 -0.44 4.85e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs5753037 0.653 rs131277 chr22:30154101 C/A cg01021169 chr22:30184971 ASCC2 -0.31 -5.76 -0.3 1.91e-8 Type 1 diabetes; LIHC cis rs8083850 0.635 rs1367634 chr18:50864668 T/G cg24270629 chr18:50823537 DCC 0.53 8.05 0.4 1.42e-14 Intelligence (multi-trait analysis); LIHC cis rs7582720 1.000 rs72936834 chr2:203771260 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6933660 0.745 rs9322320 chr6:151751908 C/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 7.52 0.38 4.8e-13 Menarche (age at onset); LIHC cis rs6500602 0.702 rs56895104 chr16:4548132 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 8.17 0.4 6.2e-15 Schizophrenia; LIHC cis rs6728642 0.908 rs13400545 chr2:97871626 A/G cg26665480 chr2:98280029 ACTR1B -0.63 -5.88 -0.3 9.6e-9 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs7107174 1.000 rs2511155 chr11:77969223 G/A cg02023728 chr11:77925099 USP35 0.49 9.35 0.45 1.21e-18 Testicular germ cell tumor; LIHC cis rs2404602 0.716 rs12594577 chr15:76828793 A/C cg03037974 chr15:76606532 NA 0.79 16.11 0.66 7.57e-44 Blood metabolite levels; LIHC cis rs7129220 0.588 rs7938534 chr11:10105925 G/T cg01453529 chr11:10209919 SBF2 -0.4 -6.97 -0.35 1.64e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs6964587 1.000 rs58965837 chr7:91585258 T/A cg17063962 chr7:91808500 NA 1.01 19.28 0.72 1.38e-56 Breast cancer; LIHC cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC cis rs7615952 0.741 rs13314845 chr3:125644782 C/T cg05084668 chr3:125655381 ALG1L -0.6 -8.5 -0.42 6.02e-16 Blood pressure (smoking interaction); LIHC cis rs11098699 0.821 rs11735364 chr4:124185679 T/C cg09941581 chr4:124220074 SPATA5 0.31 6.16 0.32 2.01e-9 Mosquito bite size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03385846 chr16:77756558 NUDT7 0.44 6.1 0.31 2.91e-9 Lung function (FEV1/FVC); LIHC cis rs6952808 0.609 rs6950151 chr7:1953521 T/C cg20295408 chr7:1910781 MAD1L1 -0.51 -7.56 -0.38 3.81e-13 Bipolar disorder and schizophrenia; LIHC cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg09913183 chr17:42254507 C17orf65;ASB16 0.8 12.48 0.56 9.98e-30 Total body bone mineral density; LIHC trans rs116095464 0.558 rs9687898 chr5:253952 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs12908161 1.000 rs11632465 chr15:85282045 A/T cg17507749 chr15:85114479 UBE2QP1 0.63 7.3 0.37 2e-12 Schizophrenia; LIHC cis rs67460515 0.563 rs6772723 chr3:160895074 C/G cg17135325 chr3:160939158 NMD3 0.59 8.4 0.41 1.18e-15 Parkinson's disease; LIHC cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs3825199 0.515 rs2072593 chr12:93970026 T/C cg18151635 chr12:93972918 NA -0.51 -8.56 -0.42 3.86e-16 Height; LIHC cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg17971929 chr21:40555470 PSMG1 -0.42 -6.28 -0.32 1.02e-9 Cognitive function; LIHC cis rs10504073 0.669 rs818558 chr8:50030855 A/G cg00325661 chr8:49890786 NA 0.32 7.29 0.37 2.14e-12 Blood metabolite ratios; LIHC cis rs2991971 0.967 rs644915 chr1:46007002 T/C cg24296786 chr1:45957014 TESK2 0.51 7.66 0.38 1.93e-13 High light scatter reticulocyte count; LIHC trans rs2243480 1.000 rs781149 chr7:65481284 C/T cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs4407350 0.870 rs4823327 chr22:44908708 T/C cg04154583 chr22:44889756 LDOC1L 0.3 6.0 0.31 4.95e-9 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg03806693 chr22:41940476 POLR3H -1.08 -11.42 -0.53 8.04e-26 Vitiligo; LIHC cis rs12142240 0.698 rs61519400 chr1:46855298 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.77 0.3 1.82e-8 Menopause (age at onset); LIHC cis rs2439831 0.850 rs28413704 chr15:44148427 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.91 0.35 2.41e-11 Lung cancer in ever smokers; LIHC cis rs11966931 0.711 rs4945790 chr6:108109985 C/T cg04749840 chr6:108095067 SCML4 -0.32 -5.75 -0.3 2.03e-8 Neutrophil percentage of white cells; LIHC cis rs11229555 0.874 rs11229519 chr11:58310587 C/T cg15696309 chr11:58395628 NA -0.72 -8.86 -0.43 4.33e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs919433 0.963 rs12469546 chr2:198178826 T/C cg03934865 chr2:198174659 NA -0.57 -9.2 -0.45 3.7e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4665809 1.000 rs6546768 chr2:26328800 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.72 -0.43 1.26e-16 Gut microbiome composition (summer); LIHC cis rs2228479 0.717 rs2286392 chr16:89809549 A/G cg06558623 chr16:89946397 TCF25 0.81 11.24 0.52 3.56e-25 Skin colour saturation; LIHC cis rs1008375 1.000 rs10011865 chr4:17645710 G/A cg02297831 chr4:17616191 MED28 0.49 7.76 0.39 9.95e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2901460 0.509 rs56944298 chr2:62090001 A/G cg02183531 chr2:62113199 CCT4 -0.4 -5.88 -0.3 1e-8 Mean corpuscular volume; LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg18713687 chr3:195489789 MUC4 0.67 10.26 0.49 1.02e-21 Lung disease severity in cystic fibrosis; LIHC cis rs881375 0.678 rs1014530 chr9:123685092 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 6.3 0.32 8.9e-10 Rheumatoid arthritis; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg24846343 chr22:24311635 DDTL 0.68 12.98 0.57 1.38e-31 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6502050 0.769 rs4789741 chr17:80119184 A/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs11122272 0.735 rs2790876 chr1:231536033 C/T cg06096015 chr1:231504339 EGLN1 0.49 9.19 0.44 3.94e-18 Hemoglobin concentration; LIHC cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.16 0.36 5.07e-12 Electroencephalogram traits; LIHC cis rs3011225 0.683 rs4660753 chr1:44321044 G/A cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Amyotrophic lateral sclerosis (age of onset); LIHC cis rs875971 0.862 rs937494 chr7:65764678 T/A cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC trans rs1945213 0.694 rs17149976 chr11:55839746 T/C cg15704280 chr7:45808275 SEPT13 0.59 7.58 0.38 3.25e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.71 -12.56 -0.56 5.15e-30 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs8014204 0.869 rs2070599 chr14:75361177 C/G cg08847533 chr14:75593920 NEK9 -0.39 -6.55 -0.33 2.07e-10 Caffeine consumption; LIHC cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg16822855 chr3:40428330 ENTPD3 -0.31 -5.76 -0.3 1.87e-8 Renal cell carcinoma; LIHC cis rs16958440 1.000 rs16958701 chr18:44655241 T/C cg17192377 chr18:44677553 HDHD2 0.6 6.74 0.34 6.88e-11 Sitting height ratio; LIHC cis rs7520050 0.808 rs11211196 chr1:46282296 A/T cg03146154 chr1:46216737 IPP -0.39 -6.51 -0.33 2.69e-10 Red blood cell count;Reticulocyte count; LIHC cis rs17685 0.712 rs60232511 chr7:75800082 A/G cg01364799 chr7:75623366 TMEM120A -0.52 -7.73 -0.39 1.19e-13 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs57221529 0.766 rs17497684 chr5:558307 T/C cg25482853 chr8:67687455 SGK3 0.67 6.67 0.34 1.03e-10 Lung disease severity in cystic fibrosis; LIHC cis rs7914558 0.933 rs10883814 chr10:104737404 T/C cg15744005 chr10:104629667 AS3MT -0.41 -9.47 -0.46 4.73e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1348850 0.874 rs12996447 chr2:178283592 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.84 13.33 0.58 6.41e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg00091569 chr3:40428383 ENTPD3 0.39 6.62 0.34 1.43e-10 Renal cell carcinoma; LIHC cis rs919433 0.889 rs12472355 chr2:198205840 C/A cg03934865 chr2:198174659 NA -0.56 -8.75 -0.43 9.76e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs17102884 0.506 rs4899540 chr14:75403408 G/A cg11812906 chr14:75593930 NEK9 -0.47 -7.97 -0.4 2.34e-14 Neuroticism; LIHC trans rs1973993 0.662 rs2057427 chr1:96888897 C/G cg10631902 chr5:14652156 NA -0.3 -6.42 -0.33 4.43e-10 Weight; LIHC cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg23221052 chr5:179740743 GFPT2 -0.42 -6.04 -0.31 4.01e-9 Height; LIHC cis rs3096299 0.679 rs3102338 chr16:89442250 C/G cg06640241 chr16:89574553 SPG7 0.59 9.11 0.44 7.08e-18 Multiple myeloma (IgH translocation); LIHC cis rs6430585 0.583 rs59243420 chr2:136584538 A/T cg15123519 chr2:136567270 LCT -0.38 -5.84 -0.3 1.23e-8 Corneal structure; LIHC cis rs6502050 0.835 rs8065565 chr17:80115399 A/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.68e-9 Life satisfaction; LIHC cis rs9790314 1.000 rs1993891 chr3:161047467 A/G cg03342759 chr3:160939853 NMD3 -0.69 -8.39 -0.41 1.25e-15 Morning vs. evening chronotype; LIHC cis rs7772486 0.790 rs7753092 chr6:146248863 C/T cg23711669 chr6:146136114 FBXO30 -0.71 -12.4 -0.56 2.03e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs1448094 0.512 rs6539932 chr12:86247497 T/C cg02569458 chr12:86230093 RASSF9 0.46 6.21 0.32 1.55e-9 Major depressive disorder; LIHC cis rs3853824 1.000 rs6503765 chr17:54880572 C/T cg13675837 chr17:54910204 DGKE 0.39 5.91 0.3 8.15e-9 Inflammatory bowel disease;Crohn's disease; LIHC trans rs1005277 0.557 rs2983338 chr10:38550734 C/T cg27523141 chr10:43048294 ZNF37B 0.4 6.74 0.34 6.92e-11 Extrinsic epigenetic age acceleration; LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg26338869 chr17:61819248 STRADA 0.53 7.18 0.36 4.41e-12 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00894870 chr1:19578612 MRTO4;KIAA0090 0.43 6.22 0.32 1.42e-9 Pancreatic cancer; LIHC cis rs2777491 0.574 rs11635906 chr15:41779260 A/G cg18705301 chr15:41695430 NDUFAF1 -1.19 -15.98 -0.65 2.44e-43 Ulcerative colitis; LIHC cis rs10193935 0.901 rs6733914 chr2:42674741 A/G cg27598129 chr2:42591480 NA 0.71 10.43 0.49 2.77e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg06138931 chr13:21896616 NA 0.51 8.7 0.43 1.42e-16 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg20415828 chr12:123011764 RSRC2;KNTC1 -0.43 -6.52 -0.33 2.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6516091 0.778 rs62199231 chr20:6050133 C/T cg25325723 chr20:6104886 FERMT1 -0.71 -5.88 -0.3 9.8e-9 Abdominal aortic aneurysm; LIHC cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg06466757 chr4:1255808 NA 0.34 5.82 0.3 1.32e-8 Obesity-related traits; LIHC cis rs4907240 0.925 rs11164109 chr2:97300833 T/A cg26665480 chr2:98280029 ACTR1B -0.41 -6.02 -0.31 4.39e-9 Event-related brain oscillations; LIHC cis rs2282032 0.527 rs57011283 chr14:90767165 G/T cg04374321 chr14:90722782 PSMC1 0.49 7.09 0.36 7.5e-12 Longevity; LIHC cis rs2250402 0.510 rs8031319 chr15:40323692 A/G cg20255370 chr15:40268687 EIF2AK4 -0.53 -6.05 -0.31 3.8e-9 Corneal curvature; LIHC trans rs1997066 0.920 rs11812127 chr10:106722433 T/C cg21239439 chr6:170038665 WDR27 0.67 6.08 0.31 3.23e-9 Diabetic kidney disease; LIHC trans rs11098499 0.645 rs78422072 chr4:120281042 C/T cg25214090 chr10:38739885 LOC399744 0.5 7.68 0.38 1.7e-13 Corneal astigmatism; LIHC cis rs1395 0.778 rs4665959 chr2:27443256 C/T cg23587288 chr2:27483067 SLC30A3 -0.33 -6.02 -0.31 4.49e-9 Blood metabolite levels; LIHC cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg02891314 chr5:179741120 GFPT2 -0.42 -5.88 -0.3 9.59e-9 Height; LIHC cis rs11098499 0.645 rs72676059 chr4:120290828 C/G cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs10463316 0.894 rs6579866 chr5:150762524 A/G cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.02e-10 Metabolite levels (Pyroglutamine); LIHC cis rs4073582 0.595 rs801737 chr11:65928193 T/C cg14036092 chr11:66035641 RAB1B 0.4 6.02 0.31 4.46e-9 Gout; LIHC cis rs7914558 0.966 rs3977751 chr10:104920232 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg06481639 chr22:41940642 POLR3H -0.71 -7.09 -0.36 7.81e-12 Vitiligo; LIHC cis rs9616064 0.557 rs9615397 chr22:47049086 C/T cg05621596 chr22:47072043 GRAMD4 -0.69 -10.68 -0.5 3.52e-23 Urate levels in obese individuals; LIHC trans rs7939886 0.920 rs1586014 chr11:55771540 C/T cg15704280 chr7:45808275 SEPT13 0.64 6.13 0.31 2.45e-9 Myopia (pathological); LIHC cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg07414643 chr4:187882934 NA 0.24 6.19 0.32 1.71e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9522267 0.535 rs2039916 chr13:112238863 A/C cg10483660 chr13:112241077 NA -0.22 -5.84 -0.3 1.21e-8 Hepatitis; LIHC cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg15320075 chr8:145703422 NA -0.62 -11.86 -0.54 2.15e-27 Age at first birth; LIHC cis rs10791097 0.668 rs10791102 chr11:130744977 G/A cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9372253 1.000 rs9372253 chr6:110716136 C/T cg00083206 chr6:110721305 DDO -0.32 -6.49 -0.33 3.02e-10 Platelet distribution width; LIHC cis rs9303401 0.659 rs66514313 chr17:56714057 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs34330 0.562 rs7486387 chr12:12866911 G/A cg09462578 chr12:12878428 APOLD1 -0.8 -10.64 -0.5 5.02e-23 Systemic lupus erythematosus; LIHC cis rs875971 0.965 rs6971509 chr7:65714970 G/T cg18876405 chr7:65276391 NA -0.38 -6.73 -0.34 7.21e-11 Aortic root size; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg03874509 chr1:107600012 PRMT6 -0.69 -10.64 -0.5 5.04e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs427394 0.632 rs169285 chr5:6736587 G/C cg10857441 chr5:6722123 POLS -0.39 -6.54 -0.33 2.29e-10 Menopause (age at onset); LIHC trans rs7618501 0.633 rs7621026 chr3:49975334 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.55 8.98 0.44 1.87e-17 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.807 rs3013594 chr1:46138000 T/C cg03146154 chr1:46216737 IPP 0.49 8.35 0.41 1.74e-15 Red blood cell count;Reticulocyte count; LIHC cis rs1005277 0.522 rs7090858 chr10:38003670 A/C cg00409905 chr10:38381863 ZNF37A 0.55 9.64 0.46 1.26e-19 Extrinsic epigenetic age acceleration; LIHC cis rs2228479 0.850 rs17226512 chr16:89839976 T/C cg14709524 chr16:89940631 TCF25 0.47 5.79 0.3 1.58e-8 Skin colour saturation; LIHC trans rs911555 0.755 rs4906329 chr14:103942669 A/G cg17675199 chr6:35436792 RPL10A -0.45 -9.16 -0.44 4.71e-18 Intelligence (multi-trait analysis); LIHC cis rs7116495 0.609 rs73531955 chr11:71687794 A/C cg10381502 chr11:71823885 C11orf51 1.02 8.51 0.42 5.38e-16 Severe influenza A (H1N1) infection; LIHC cis rs526821 0.553 rs295597 chr11:55470003 T/C cg04317927 chr11:55418816 OR4S2 0.44 8.17 0.4 5.93e-15 Pediatric bone mineral density (spine); LIHC cis rs4908768 0.911 rs12567592 chr1:8788907 C/T cg20416874 chr1:8611966 RERE 0.52 7.59 0.38 3.01e-13 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2806561 0.514 rs11801120 chr1:23543307 C/T cg19743168 chr1:23544995 NA 0.41 5.92 0.31 7.62e-9 Height; LIHC cis rs507080 0.663 rs523793 chr11:118570697 C/T cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs116095464 0.558 rs9654453 chr5:299621 T/C cg22496380 chr5:211416 CCDC127 -1.09 -10.06 -0.48 4.85e-21 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17427198 chr6:52529191 LOC730101 0.44 6.25 0.32 1.19e-9 Cognitive function; LIHC cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg13395646 chr4:1353034 KIAA1530 0.63 9.11 0.44 7.15e-18 Obesity-related traits; LIHC cis rs1008375 1.000 rs1558378 chr4:17650351 T/C cg02297831 chr4:17616191 MED28 0.5 7.8 0.39 7.38e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8084351 0.577 rs9949889 chr18:50608436 A/G cg24270629 chr18:50823537 DCC -0.46 -7.04 -0.36 1.03e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs6582630 0.555 rs10880612 chr12:38509427 A/G cg13010199 chr12:38710504 ALG10B 0.46 6.22 0.32 1.42e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs6088590 1.000 rs3787222 chr20:33333040 T/A cg06115741 chr20:33292138 TP53INP2 0.6 8.6 0.42 2.95e-16 Coronary artery disease; LIHC cis rs7249142 0.597 rs7250650 chr19:19285989 A/T cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.35 -5.91 -0.3 8.13e-9 IgG glycosylation; LIHC cis rs2439831 1.000 rs2439850 chr15:43784854 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.78 13.15 0.58 3.07e-32 Lung cancer in ever smokers; LIHC cis rs9457247 0.582 rs9459855 chr6:167466150 G/T cg23791538 chr6:167370224 RNASET2 -0.51 -7.81 -0.39 6.86e-14 Crohn's disease; LIHC cis rs9649465 1.000 rs1468656 chr7:123375505 G/C cg03229431 chr7:123269106 ASB15 -0.37 -7.99 -0.4 2.03e-14 Migraine; LIHC cis rs16958440 0.867 rs114475395 chr18:44691010 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs12286929 0.590 rs4936322 chr11:115061533 T/C cg04055981 chr11:115044050 NA 0.39 6.46 0.33 3.56e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2991971 0.967 rs60608374 chr1:46008913 G/A cg24296786 chr1:45957014 TESK2 0.53 7.93 0.39 3.05e-14 High light scatter reticulocyte count; LIHC cis rs2235642 0.821 rs2281236 chr16:1603576 G/A cg03034668 chr16:1723424 CRAMP1L -0.41 -7.27 -0.37 2.47e-12 Coronary artery disease; LIHC cis rs2242116 0.793 rs9855938 chr3:46957298 G/A cg23352942 chr3:46931381 PTH1R -0.29 -7.32 -0.37 1.84e-12 Birth weight; LIHC cis rs1957429 0.808 rs1570296 chr14:65332294 T/A cg23373153 chr14:65346875 NA 0.8 11.31 0.52 2.12e-25 Pediatric areal bone mineral density (radius); LIHC cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg06640241 chr16:89574553 SPG7 0.85 15.59 0.64 8.92e-42 Multiple myeloma (IgH translocation); LIHC cis rs6500602 0.647 rs3747600 chr16:4586222 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.71 0.3 2.45e-8 Schizophrenia; LIHC cis rs16958440 0.867 rs80064497 chr18:44669653 A/G cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs8017423 0.967 rs12896540 chr14:90729392 T/C cg04374321 chr14:90722782 PSMC1 -0.78 -14.98 -0.63 2.41e-39 Mortality in heart failure; LIHC cis rs9399135 0.967 rs6908512 chr6:135367757 A/G cg24558204 chr6:135376177 HBS1L 0.42 6.81 0.35 4.49e-11 Red blood cell count; LIHC cis rs7072216 0.763 rs10883090 chr10:100167236 G/C cg26618903 chr10:100175079 PYROXD2 -0.39 -6.23 -0.32 1.41e-9 Metabolite levels; LIHC cis rs7264396 0.635 rs2024854 chr20:34511189 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -10.59 -0.5 7.71e-23 Total cholesterol levels; LIHC cis rs986417 1.000 rs1254322 chr14:60906976 G/A cg27398547 chr14:60952738 C14orf39 -0.76 -8.61 -0.42 2.66e-16 Gut microbiota (bacterial taxa); LIHC cis rs9581857 0.579 rs3759433 chr13:27997999 C/T cg22138327 chr13:27999177 GTF3A 0.54 7.74 0.39 1.16e-13 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs2073300 0.609 rs6137913 chr20:23357725 C/T cg16736954 chr20:23401023 NAPB 0.68 8.16 0.4 6.32e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7659604 0.539 rs11098645 chr4:122729251 G/A cg19748678 chr4:122722346 EXOSC9 0.67 10.96 0.51 3.65e-24 Type 2 diabetes; LIHC cis rs10540 1.000 rs116876680 chr11:517473 G/T cg03352830 chr11:487213 PTDSS2 0.79 6.39 0.33 5.48e-10 Body mass index; LIHC cis rs17428076 0.874 rs72885532 chr2:172684033 A/G cg13550731 chr2:172543902 DYNC1I2 0.38 6.21 0.32 1.54e-9 Myopia; LIHC cis rs60871478 1.000 rs34086011 chr7:805430 C/T cg05535760 chr7:792225 HEATR2 0.79 11.27 0.52 2.85e-25 Cerebrospinal P-tau181p levels; LIHC cis rs6684514 1.000 rs2277870 chr1:156246792 C/T cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs919433 0.617 rs10931791 chr2:198573612 A/C cg10820045 chr2:198174542 NA -0.47 -7.02 -0.36 1.17e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs2836950 0.527 rs2836958 chr21:40623526 T/C cg11890956 chr21:40555474 PSMG1 -0.41 -6.65 -0.34 1.13e-10 Menarche (age at onset); LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg23131131 chr22:24373011 LOC391322 0.49 6.55 0.33 2.1e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs651907 0.535 rs34063583 chr3:101509948 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs17376456 0.877 rs10072592 chr5:93405989 C/G cg25358565 chr5:93447407 FAM172A 1.12 10.25 0.48 1.1e-21 Diabetic retinopathy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11003009 chr5:74632112 HMGCR 0.4 6.58 0.34 1.77e-10 Cognitive function; LIHC trans rs9929218 0.954 rs12596834 chr16:68823199 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.18 -0.4 5.53e-15 Colorectal cancer; LIHC cis rs7395581 0.959 rs901746 chr11:47260319 A/G cg25783544 chr11:47291846 MADD 0.43 6.21 0.32 1.52e-9 HDL cholesterol; LIHC cis rs2806561 0.780 rs12751560 chr1:23407081 C/A cg19743168 chr1:23544995 NA -0.35 -6.28 -0.32 1.02e-9 Height; LIHC cis rs4891159 0.790 rs690619 chr18:74108744 A/G cg24786174 chr18:74118243 ZNF516 0.78 13.89 0.6 4.12e-35 Longevity; LIHC cis rs970821 0.645 rs6470180 chr8:124751584 T/G cg00283535 chr8:124749564 ANXA13 -0.42 -7.44 -0.37 8.14e-13 Breast cancer; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg02782426 chr3:40428986 ENTPD3 -0.35 -6.48 -0.33 3.13e-10 Renal cell carcinoma; LIHC cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00287636 chr16:49892218 NA 0.42 6.19 0.32 1.75e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.8e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2257205 0.667 rs75982345 chr17:56708836 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.24 -0.32 1.31e-9 Pancreatic cancer; LIHC cis rs6089584 0.888 rs6061983 chr20:60621202 T/C cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC cis rs1570884 0.516 rs9316462 chr13:50176321 A/G cg03651054 chr13:50194643 NA 0.37 6.61 0.34 1.46e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs763121 0.853 rs5757196 chr22:39039855 G/C cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs1008375 0.863 rs10003291 chr4:17600728 A/C cg16339924 chr4:17578868 LAP3 0.51 6.68 0.34 9.85e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg12463550 chr7:65579703 CRCP 0.67 6.86 0.35 3.29e-11 Diabetic kidney disease; LIHC trans rs2832191 0.692 rs2254872 chr21:30414724 C/T cg14791747 chr16:20752902 THUMPD1 -0.49 -6.88 -0.35 2.94e-11 Dental caries; LIHC cis rs4808199 0.895 rs8105094 chr19:19374061 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.34 0.37 1.56e-12 Nonalcoholic fatty liver disease; LIHC cis rs763014 0.966 rs12935215 chr16:670605 T/C cg27189623 chr16:705930 WDR90 0.42 6.91 0.35 2.43e-11 Height; LIHC cis rs9818758 0.607 rs34343820 chr3:49309534 C/G cg07636037 chr3:49044803 WDR6 -0.82 -8.32 -0.41 2.09e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9911578 1.000 rs9901114 chr17:56575208 G/A cg05425664 chr17:57184151 TRIM37 0.57 8.51 0.42 5.56e-16 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22994272 chr14:104346241 NA 0.46 7.1 0.36 7.08e-12 Pancreatic cancer; LIHC cis rs858239 0.539 rs7791200 chr7:23182121 A/T cg23682824 chr7:23144976 KLHL7 0.42 6.23 0.32 1.37e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7829975 0.606 rs891570 chr8:8794454 G/A cg06636001 chr8:8085503 FLJ10661 -0.41 -6.48 -0.33 3.22e-10 Mood instability; LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg12016809 chr21:47604291 C21orf56 0.49 7.65 0.38 2.01e-13 Testicular germ cell tumor; LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg13395646 chr4:1353034 KIAA1530 0.41 5.8 0.3 1.51e-8 Longevity; LIHC cis rs6752107 1.000 rs6431654 chr2:234161769 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.57 8.98 0.44 1.78e-17 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9457247 0.935 rs9348211 chr6:167375173 G/C cg07741184 chr6:167504864 NA -0.29 -6.7 -0.34 8.84e-11 Crohn's disease; LIHC cis rs1712517 0.740 rs4293062 chr10:105052624 G/A cg05636881 chr10:105038444 INA 0.46 7.01 0.35 1.31e-11 Migraine; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08127460 chr7:156931776 UBE3C -0.4 -6.08 -0.31 3.17e-9 Calcium levels; LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg13152130 chr6:118910203 C6orf204 0.62 6.84 0.35 3.7e-11 Diastolic blood pressure; LIHC trans rs10028773 0.556 rs4473640 chr4:120260437 G/A cg25214090 chr10:38739885 LOC399744 0.45 7.39 0.37 1.14e-12 Educational attainment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26316544 chr3:52188418 WDR51A 0.42 6.29 0.32 9.7e-10 Lung function (FEV1/FVC); LIHC cis rs4631830 0.965 rs7070301 chr10:51543070 T/G cg20129853 chr10:51489980 NA -0.4 -8.6 -0.42 2.94e-16 Prostate-specific antigen levels; LIHC cis rs2073300 1.000 rs6048825 chr20:23457671 T/C cg12062639 chr20:23401060 NAPB 0.78 9.7 0.46 8.37e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3812831 0.543 rs389108 chr13:114925389 A/G cg08824895 chr13:115047677 UPF3A 0.48 6.86 0.35 3.32e-11 Schizophrenia; LIHC cis rs7772486 0.641 rs2748489 chr6:146331287 T/G cg13319975 chr6:146136371 FBXO30 -0.54 -8.6 -0.42 2.88e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs739401 0.572 rs389285 chr11:3062673 G/A cg08508325 chr11:3079039 CARS -0.35 -7.57 -0.38 3.48e-13 Longevity; LIHC cis rs3106136 0.678 rs7674215 chr4:95294145 C/A cg11021082 chr4:95130006 SMARCAD1 0.34 5.9 0.3 8.94e-9 Capecitabine sensitivity; LIHC cis rs12220238 1.000 rs10824106 chr10:75958408 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.66 -6.31 -0.32 8.45e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7674212 0.540 rs2720469 chr4:104086484 C/T cg16532752 chr4:104119610 CENPE -0.46 -7.22 -0.36 3.29e-12 Type 2 diabetes; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg27543739 chr10:94334014 IDE 0.51 6.67 0.34 1.06e-10 Hepatitis; LIHC cis rs4555082 0.834 rs2816607 chr14:105718385 A/T cg13114125 chr14:105738426 BRF1 -0.79 -10.09 -0.48 4e-21 Mean platelet volume;Platelet distribution width; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg01191815 chr15:63084959 TLN2 -0.46 -6.66 -0.34 1.08e-10 Alcohol dependence; LIHC cis rs7666738 0.830 rs9996098 chr4:98867740 T/C cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg14671364 chr1:107599128 PRMT6 0.45 6.17 0.32 1.9e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1419980 0.630 rs2080126 chr12:7774524 A/C cg25828445 chr12:7781288 NA 0.44 6.86 0.35 3.33e-11 HDL cholesterol levels; LIHC cis rs7843479 0.601 rs10866827 chr8:21801141 G/A cg17168535 chr8:21777572 XPO7 0.59 10.68 0.5 3.59e-23 Mean corpuscular volume; LIHC trans rs1814175 0.817 rs7927373 chr11:49957640 A/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.05 -0.78 1.27e-71 Height; LIHC cis rs17253792 0.915 rs74580958 chr14:56181511 G/A cg01858014 chr14:56050164 KTN1 -0.75 -7.41 -0.37 9.7e-13 Putamen volume; LIHC cis rs35306767 0.807 rs72778228 chr10:938435 A/G cg26597838 chr10:835615 NA 1.45 16.45 0.66 3.18e-45 Eosinophil percentage of granulocytes; LIHC cis rs1843834 0.539 rs12694643 chr2:225446603 A/G cg22509189 chr2:225307070 NA -0.81 -11.39 -0.52 1.07e-25 IgE levels in asthmatics (D.p. specific); LIHC cis rs2242116 0.900 rs1001284 chr3:46933960 C/G cg02527881 chr3:46936655 PTH1R -0.54 -11.73 -0.54 6.07e-27 Birth weight; LIHC cis rs5753618 0.509 rs5749229 chr22:31587218 T/C cg07713946 chr22:31675144 LIMK2 -0.42 -7.41 -0.37 9.8e-13 Colorectal cancer; LIHC cis rs7246657 0.943 rs4802766 chr19:37981933 T/C cg23950597 chr19:37808831 NA -0.5 -6.41 -0.33 4.94e-10 Coronary artery calcification; LIHC cis rs4908768 0.539 rs1061039 chr1:8642588 T/C cg20416874 chr1:8611966 RERE -0.64 -12.59 -0.56 4.06e-30 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2629540 0.781 rs2293064 chr10:126396511 C/G cg08799069 chr10:126477246 METTL10 0.36 5.73 0.3 2.17e-8 Cocaine dependence; LIHC cis rs151997 0.925 rs28077 chr5:50191946 T/A cg06027927 chr5:50259733 NA 0.57 7.72 0.39 1.28e-13 Callous-unemotional behaviour; LIHC cis rs2439831 0.867 rs7170489 chr15:43636651 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg20887711 chr4:1340912 KIAA1530 0.47 7.13 0.36 6.06e-12 Obesity-related traits; LIHC cis rs10791323 0.569 rs1119851 chr11:133742842 T/C cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.58e-9 Childhood ear infection; LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.47 -6.74 -0.34 6.9e-11 Lymphocyte counts; LIHC cis rs412000 0.553 rs2680702 chr17:56431549 A/G cg12560992 chr17:57184187 TRIM37 0.54 7.17 0.36 4.62e-12 Primary tooth development (time to first tooth eruption); LIHC cis rs17292804 0.527 rs12887734 chr14:104046834 G/T cg24130564 chr14:104152367 KLC1 -0.54 -8.82 -0.43 6.01e-17 Autism spectrum disorder or schizophrenia; LIHC cis rs1003719 0.680 rs7275984 chr21:38505696 C/A cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.46e-25 Eye color traits; LIHC cis rs12142240 0.698 rs67276232 chr1:46825484 T/G cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs2273669 0.588 rs111773102 chr6:109306480 C/T cg05315195 chr6:109294784 ARMC2 -0.52 -5.76 -0.3 1.88e-8 Prostate cancer; LIHC cis rs17854409 0.764 rs16983293 chr20:61479056 A/G cg05147244 chr20:61493195 TCFL5 1.23 10.37 0.49 4.35e-22 Obesity-related traits; LIHC cis rs11233413 1.000 rs11233415 chr11:82725037 A/C cg24227371 chr11:82718527 RAB30 -0.35 -7.74 -0.39 1.11e-13 Economic and political preferences (feminism/equality); LIHC cis rs12477438 0.559 rs6733285 chr2:99725575 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs12701220 0.522 rs868833 chr7:1054973 C/G cg09177884 chr7:1199841 ZFAND2A -0.45 -5.73 -0.3 2.19e-8 Bronchopulmonary dysplasia; LIHC cis rs919433 0.617 rs2037590 chr2:198584775 T/A cg10820045 chr2:198174542 NA -0.51 -7.8 -0.39 7.41e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9399135 0.967 rs6902438 chr6:135336587 C/T cg24558204 chr6:135376177 HBS1L 0.41 6.8 0.35 4.73e-11 Red blood cell count; LIHC cis rs4555082 0.957 rs3000073 chr14:105729792 G/A cg10792982 chr14:105748885 BRF1 0.44 6.17 0.32 1.94e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs2274273 0.806 rs7146752 chr14:55738907 A/G cg01864836 chr14:55583639 NA -0.41 -7.44 -0.37 8.07e-13 Protein biomarker; LIHC cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg05564831 chr3:52568323 NT5DC2 0.37 5.91 0.3 8.19e-9 Bipolar disorder; LIHC cis rs904251 0.523 rs10807184 chr6:37483713 C/T cg01843034 chr6:37503916 NA -0.46 -7.84 -0.39 5.95e-14 Cognitive performance; LIHC cis rs8180040 0.726 rs11130110 chr3:47000606 T/C cg02527881 chr3:46936655 PTH1R -0.35 -7.02 -0.35 1.2e-11 Colorectal cancer; LIHC cis rs57590327 0.527 rs9845467 chr3:81614473 G/A cg07356753 chr3:81810745 GBE1 -0.55 -8.41 -0.41 1.09e-15 Extraversion; LIHC cis rs4144743 0.759 rs4289057 chr17:45321030 G/A cg18085866 chr17:45331354 ITGB3 -0.6 -7.02 -0.35 1.18e-11 Body mass index; LIHC cis rs7617773 0.817 rs35414021 chr3:48293524 G/C cg11946769 chr3:48343235 NME6 0.89 11.15 0.52 8.01e-25 Coronary artery disease; LIHC cis rs9640161 0.617 rs73170169 chr7:150008036 G/A cg17279839 chr7:150038598 RARRES2 0.55 11.03 0.51 2.16e-24 Blood protein levels;Circulating chemerin levels; LIHC cis rs4268898 0.636 rs72787383 chr2:24583861 G/A cg06627628 chr2:24431161 ITSN2 -0.74 -9.62 -0.46 1.53e-19 Asthma; LIHC cis rs4803468 1.000 rs11670668 chr19:41920454 G/C cg14132834 chr19:41945861 ATP5SL -0.43 -6.4 -0.33 5.17e-10 Height; LIHC cis rs3740540 0.507 rs942014 chr10:126290070 C/T cg04949429 chr10:126290192 LHPP 0.45 7.34 0.37 1.6e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs72627509 0.904 rs56281640 chr4:57765816 G/A cg26694713 chr4:57773883 REST 0.75 10.7 0.5 3.19e-23 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7149337 0.933 rs28705789 chr14:51713508 C/T cg23942311 chr14:51606299 NA 0.34 6.61 0.34 1.47e-10 Cancer; LIHC cis rs1577917 0.771 rs2484355 chr6:86394403 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.97 -0.4 2.36e-14 Response to antipsychotic treatment; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs898097 0.627 rs3785514 chr17:80888905 A/G cg15664640 chr17:80829946 TBCD 0.68 10.88 0.51 7.27e-24 Breast cancer; LIHC cis rs11888559 0.511 rs1560855 chr2:204036063 T/C cg24605529 chr2:203879461 NBEAL1 0.76 5.81 0.3 1.44e-8 Height; LIHC cis rs3784262 0.900 rs12911071 chr15:58314848 G/A cg12031962 chr15:58353849 ALDH1A2 -0.34 -6.6 -0.34 1.53e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.91 8.42 0.41 1.01e-15 Platelet count; LIHC cis rs7412746 0.621 rs72704656 chr1:150828307 A/G cg18016565 chr1:150552671 MCL1 0.55 10.29 0.49 7.91e-22 Melanoma; LIHC cis rs7224685 0.506 rs12452569 chr17:4023667 T/A cg09597638 chr17:3907349 NA 0.55 6.75 0.34 6.32e-11 Type 2 diabetes; LIHC cis rs875971 0.545 rs2707851 chr7:66089165 C/T cg11764359 chr7:65958608 NA -0.61 -8.71 -0.43 1.33e-16 Aortic root size; LIHC cis rs2834081 0.536 rs11702285 chr21:34474294 G/A cg00274965 chr21:34405681 NA 0.4 6.37 0.33 6.05e-10 Sum eosinophil basophil counts; LIHC cis rs35883536 0.647 rs1335765 chr1:101048612 A/T cg14515779 chr1:101123966 NA 0.49 6.75 0.34 6.22e-11 Monocyte count; LIHC cis rs508618 0.731 rs576462 chr1:231544607 C/T cg06096015 chr1:231504339 EGLN1 0.42 7.17 0.36 4.68e-12 Red blood cell count; LIHC cis rs67311347 1.000 rs9842564 chr3:40405810 A/G cg00656387 chr3:40428638 ENTPD3 -0.37 -6.18 -0.32 1.79e-9 Renal cell carcinoma; LIHC cis rs3540 0.533 rs12708585 chr15:91052285 C/T cg22089800 chr15:90895588 ZNF774 -0.56 -8.06 -0.4 1.26e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs875971 0.638 rs801205 chr7:66022144 C/A cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs921968 0.541 rs576901 chr2:219424364 A/G cg02985541 chr2:219472218 PLCD4 0.42 6.88 0.35 2.87e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg05484376 chr2:27715224 FNDC4 0.36 5.93 0.31 7.33e-9 Total body bone mineral density; LIHC cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6076065 0.748 rs6137933 chr20:23383103 A/T cg11657817 chr20:23433608 CST11 0.32 6.73 0.34 7.35e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs2637030 0.533 rs7731940 chr5:52863638 A/T cg06476337 chr5:52856530 NDUFS4 0.41 6.57 0.33 1.86e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs8067545 0.641 rs860335 chr17:19837679 A/G cg13482628 chr17:19912719 NA 0.38 6.21 0.32 1.5e-9 Schizophrenia; LIHC cis rs611744 0.967 rs608115 chr8:109231948 T/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC trans rs2352908 1.000 rs2352913 chr14:49453094 T/C cg16568472 chr20:3190600 ITPA -0.45 -6.07 -0.31 3.37e-9 Social communication problems; LIHC cis rs701145 0.529 rs355759 chr3:154008078 G/C cg16511985 chr3:153974050 SGEF 0.42 8.8 0.43 7.09e-17 Coronary artery disease; LIHC cis rs2235642 0.859 rs12599207 chr16:1606445 A/G cg09065629 chr16:1709722 CRAMP1L 0.32 5.74 0.3 2.09e-8 Coronary artery disease; LIHC cis rs5769765 0.773 rs7410291 chr22:50300078 A/G cg26441486 chr22:50317300 CRELD2 0.35 6.18 0.32 1.81e-9 Schizophrenia; LIHC cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg11987759 chr7:65425863 GUSB -0.39 -6.12 -0.31 2.5e-9 Calcium levels; LIHC cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg10560079 chr2:191398806 TMEM194B -0.5 -7.74 -0.39 1.13e-13 Pulse pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11489389 chr3:63849240 ATXN7;THOC7 0.43 6.3 0.32 9.06e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg26347064 chr19:45211248 CEACAM16 0.37 6.2 0.32 1.64e-9 Immature fraction of reticulocytes; LIHC cis rs916888 0.738 rs199515 chr17:44856641 C/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.62 -6.14 -0.31 2.32e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18679886 chr7:107531975 DLD 0.41 6.07 0.31 3.44e-9 Pancreatic cancer; LIHC cis rs7523273 0.512 rs2761435 chr1:207918466 C/G cg22525895 chr1:207977042 MIR29B2 0.5 7.99 0.4 2.14e-14 Schizophrenia; LIHC trans rs800082 1.000 rs1405597 chr3:144314276 A/C cg24215973 chr2:240111563 HDAC4 -0.42 -6.18 -0.32 1.79e-9 Smoking behavior; LIHC cis rs4919694 1.000 rs17881215 chr10:104629236 G/C cg04362960 chr10:104952993 NT5C2 0.69 7.32 0.37 1.75e-12 Arsenic metabolism; LIHC cis rs758324 0.947 rs804059 chr5:131270136 T/C cg06307176 chr5:131281290 NA -0.4 -5.77 -0.3 1.74e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs10876993 0.928 rs2640637 chr12:58077586 G/A cg18357645 chr12:58087776 OS9 0.53 8.7 0.43 1.41e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs1034435 0.755 rs5767171 chr22:48891881 A/G cg05992904 chr22:48892994 FAM19A5 -0.52 -10.61 -0.5 6.19e-23 Late-onset Alzheimer's disease; LIHC cis rs10489202 1.000 rs1060041 chr1:167973976 C/T cg24449463 chr1:168025552 DCAF6 -0.48 -6.51 -0.33 2.73e-10 Schizophrenia; LIHC cis rs6430585 0.583 rs12472293 chr2:136648077 T/C cg15123519 chr2:136567270 LCT -0.37 -5.86 -0.3 1.07e-8 Corneal structure; LIHC cis rs36051895 0.589 rs10491651 chr9:5200060 A/G cg02405213 chr9:5042618 JAK2 -0.64 -10.58 -0.5 8.4e-23 Pediatric autoimmune diseases; LIHC cis rs2404602 0.610 rs28823285 chr15:77050395 T/C cg03037974 chr15:76606532 NA -0.61 -10.26 -0.49 1.06e-21 Blood metabolite levels; LIHC cis rs7192750 0.652 rs150617 chr16:72139396 T/C cg14768367 chr16:72042858 DHODH 0.58 6.11 0.31 2.75e-9 LDL cholesterol levels;Total cholesterol levels; LIHC trans rs11098499 1.000 rs13435802 chr4:120177960 A/T cg25214090 chr10:38739885 LOC399744 -0.54 -8.14 -0.4 7.59e-15 Corneal astigmatism; LIHC cis rs490234 0.812 rs17259739 chr9:128456639 C/T cg14078157 chr9:128172775 NA 0.39 6.41 0.33 4.85e-10 Mean arterial pressure; LIHC trans rs7618501 1.000 rs57648519 chr3:49813169 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.82 15.18 0.63 3.93e-40 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.915 rs2842980 chr6:160100116 A/T cg26839252 chr6:160211577 TCP1;MRPL18 0.38 6.28 0.32 9.99e-10 Age-related macular degeneration (geographic atrophy); LIHC cis rs4919087 1.000 rs4919089 chr10:99087905 G/A cg25902810 chr10:99078978 FRAT1 -0.66 -9.94 -0.47 1.26e-20 Monocyte count; LIHC cis rs861020 0.527 rs614662 chr1:209962419 C/T cg22029157 chr1:209979665 IRF6 -0.46 -7.66 -0.38 1.98e-13 Orofacial clefts; LIHC cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.616 rs1862878 chr7:139019914 C/G cg07862535 chr7:139043722 LUC7L2 0.59 10.08 0.48 4.18e-21 Diisocyanate-induced asthma; LIHC cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg03188948 chr7:1209495 NA 0.75 5.95 0.31 6.8e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9372253 0.678 rs9372251 chr6:110700656 A/G cg19196401 chr6:110721138 DDO -0.33 -6.69 -0.34 9.36e-11 Platelet distribution width; LIHC cis rs919433 0.519 rs700656 chr2:198653667 T/C cg10820045 chr2:198174542 NA 0.46 6.99 0.35 1.41e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6723226 0.698 rs13409142 chr2:32666137 C/T cg02381751 chr2:32503542 YIPF4 0.67 9.97 0.47 1.02e-20 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.96 0.31 6.25e-9 Menopause (age at onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25494665 chr13:42623369 DGKH 0.4 6.13 0.31 2.38e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18123596 chr17:36956264 PIP4K2B 0.49 6.85 0.35 3.38e-11 Pancreatic cancer; LIHC cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg23262073 chr20:60523788 NA -0.3 -6.22 -0.32 1.43e-9 Body mass index; LIHC cis rs11229555 0.874 rs10896794 chr11:58339124 T/C cg15696309 chr11:58395628 NA -0.71 -8.73 -0.43 1.11e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4728302 0.869 rs958405 chr7:133597151 A/G cg10665199 chr7:133106180 EXOC4 0.38 6.64 0.34 1.21e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs3768617 0.811 rs11590958 chr1:183023636 T/C ch.1.3577855R chr1:183094577 LAMC1 0.48 7.72 0.39 1.34e-13 Fuchs's corneal dystrophy; LIHC cis rs17152411 0.895 rs61872118 chr10:126583450 C/T cg07906193 chr10:126599966 NA 0.43 6.84 0.35 3.73e-11 Height; LIHC cis rs13217239 0.646 rs12201393 chr6:26975690 C/A cg12292205 chr6:26970375 C6orf41 0.45 7.76 0.39 1.02e-13 Schizophrenia; LIHC cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs4684776 0.867 rs11706903 chr3:11343551 C/A cg00170343 chr3:11313890 ATG7 -0.52 -7.21 -0.36 3.53e-12 Small vessel stroke; LIHC cis rs7520050 0.966 rs785491 chr1:46583418 G/A cg03146154 chr1:46216737 IPP -0.37 -6.16 -0.32 1.99e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg07308232 chr7:1071921 C7orf50 -0.47 -7.61 -0.38 2.62e-13 Longevity;Endometriosis; LIHC cis rs2153535 0.580 rs7769020 chr6:8457724 G/A cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs9733 0.596 rs7529998 chr1:150662531 C/T cg18016565 chr1:150552671 MCL1 0.59 11.56 0.53 2.57e-26 Tonsillectomy; LIHC cis rs1881396 0.891 rs62131879 chr2:27755112 T/G cg27432699 chr2:27873401 GPN1 0.46 6.79 0.34 4.87e-11 Nonalcoholic fatty liver disease; LIHC cis rs11792861 0.926 rs56899598 chr9:111867271 A/G cg05043794 chr9:111880884 C9orf5 -0.31 -7.28 -0.37 2.25e-12 Menarche (age at onset); LIHC cis rs1003719 0.688 rs2835660 chr21:38568882 G/C cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs9918079 0.542 rs1789 chr4:15664535 G/A cg04067612 chr4:15429572 C1QTNF7 -0.27 -5.78 -0.3 1.64e-8 Obesity-related traits; LIHC cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg20295408 chr7:1910781 MAD1L1 -0.51 -7.18 -0.36 4.45e-12 Bipolar disorder and schizophrenia; LIHC cis rs6545883 0.965 rs766447 chr2:61735569 C/T cg15711740 chr2:61764176 XPO1 -0.42 -6.02 -0.31 4.45e-9 Tuberculosis; LIHC cis rs6754311 0.550 rs1438307 chr2:136499166 A/C cg07169764 chr2:136633963 MCM6 0.65 9.54 0.46 2.75e-19 Mosquito bite size; LIHC cis rs5030049 1 rs5030049 chr3:186450863 T/C cg12454167 chr3:186435060 KNG1 0.34 6.09 0.31 3.11e-9 Blood protein levels; LIHC cis rs2180341 1.000 rs6569479 chr6:127606588 A/G cg24812749 chr6:127587940 RNF146 1.05 15.92 0.65 4.32e-43 Breast cancer; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.55 0.62 1.1e-37 Prudent dietary pattern; LIHC cis rs7917772 0.503 rs61871067 chr10:104295382 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.74 8.7 0.43 1.43e-16 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs28647808 0.881 rs28602295 chr9:136267471 G/A cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs9810259 0.525 rs310749 chr3:12273768 A/C cg23514324 chr3:12329213 PPARG -0.45 -5.73 -0.3 2.19e-8 Platelet count; LIHC cis rs1728785 0.901 rs8050289 chr16:68566976 T/A cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs1198430 0.925 rs2510072 chr1:23769674 A/G cg13183780 chr1:23809682 ASAP3 -0.55 -7.55 -0.38 3.91e-13 Total cholesterol levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14608199 chr11:2949963 PHLDA2 0.44 6.37 0.33 6.11e-10 Lung function (FEV1/FVC); LIHC cis rs8062405 0.723 rs113208333 chr16:28606160 G/T cg16576597 chr16:28551801 NUPR1 0.46 7.02 0.35 1.24e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7772486 0.817 rs2748491 chr6:146327759 T/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.07 -0.31 3.33e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs13108904 0.846 rs3775100 chr4:1225106 T/C cg19318889 chr4:1322082 MAEA 0.42 6.5 0.33 2.78e-10 Obesity-related traits; LIHC cis rs7772486 0.875 rs9390372 chr6:146363638 G/C cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.21e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs16912285 0.688 rs59797575 chr11:24315536 A/T ch.11.24196551F chr11:24239977 NA 0.76 10.03 0.48 6.44e-21 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs2286503 0.780 rs1304431 chr7:22865412 T/C cg11367502 chr7:22862612 TOMM7 0.49 8.43 0.41 9.85e-16 Fibrinogen; LIHC cis rs7613875 0.620 rs7430334 chr3:50078221 T/C cg24110177 chr3:50126178 RBM5 0.56 9.16 0.44 4.94e-18 Body mass index; LIHC cis rs7927592 0.913 rs11228293 chr11:68384646 T/C cg01657329 chr11:68192670 LRP5 -0.48 -6.21 -0.32 1.57e-9 Total body bone mineral density; LIHC cis rs754466 0.580 rs10762763 chr10:79560803 C/G cg17075019 chr10:79541650 NA -0.8 -14.64 -0.62 4.99e-38 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1461503 0.966 rs11218908 chr11:122841687 A/G cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC trans rs561341 1.000 rs537166 chr17:30326827 C/T cg20587970 chr11:113659929 NA -1.23 -10.64 -0.5 5.12e-23 Hip circumference adjusted for BMI; LIHC cis rs12188164 0.525 rs1114665 chr5:452247 C/T cg26076054 chr5:421317 AHRR 0.27 5.84 0.3 1.24e-8 Cystic fibrosis severity; LIHC cis rs11969893 0.737 rs9386262 chr6:101427687 G/T cg12253828 chr6:101329408 ASCC3 1.05 11.41 0.52 9.39e-26 Economic and political preferences (immigration/crime); LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg26338869 chr17:61819248 STRADA -0.58 -8.52 -0.42 5.15e-16 Prudent dietary pattern; LIHC cis rs694739 0.894 rs11601860 chr11:64110422 A/T cg23796481 chr11:64053134 BAD;GPR137 0.6 8.06 0.4 1.26e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs12950390 0.893 rs4239166 chr17:45847329 A/G cg03474202 chr17:45855739 NA -0.35 -6.1 -0.31 2.84e-9 IgG glycosylation; LIHC cis rs7945705 0.967 rs56316046 chr11:8876598 G/T cg21881798 chr11:8931708 C11orf17;ST5 0.43 7.29 0.37 2.2e-12 Hemoglobin concentration; LIHC cis rs8044868 1.000 rs8052408 chr16:72158077 C/T cg16558253 chr16:72132732 DHX38 -0.39 -6.27 -0.32 1.07e-9 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs2070488 0.736 rs2070988 chr3:38437835 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.53 7.63 0.38 2.42e-13 Electrocardiographic conduction measures; LIHC cis rs10832963 0.686 rs11024743 chr11:18653712 A/G cg20219074 chr11:18656078 SPTY2D1 0.83 13.67 0.59 3.06e-34 Breast cancer; LIHC cis rs9916302 0.851 rs6503502 chr17:37501855 A/G cg03013999 chr17:37608204 MED1 -0.35 -5.93 -0.31 7.41e-9 Glomerular filtration rate (creatinine); LIHC trans rs76648483 0.672 rs1138357 chr15:80263406 C/T cg11476254 chr16:89159666 ACSF3 -0.48 -6.15 -0.32 2.12e-9 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg05484376 chr2:27715224 FNDC4 0.36 6.16 0.32 2.07e-9 Total body bone mineral density; LIHC cis rs963731 0.649 rs10439459 chr2:39236983 G/T cg04010122 chr2:39346883 SOS1 -0.68 -5.76 -0.3 1.86e-8 Corticobasal degeneration; LIHC cis rs9649213 0.593 rs7807555 chr7:97957517 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.12e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs9534288 1.000 rs9534288 chr13:46605441 T/C cg15192986 chr13:46630673 CPB2 -0.57 -8.69 -0.43 1.56e-16 Blood protein levels; LIHC cis rs722599 0.501 rs7158047 chr14:75388803 G/A cg08847533 chr14:75593920 NEK9 0.59 10.35 0.49 4.97e-22 IgG glycosylation; LIHC cis rs769267 0.930 rs1054930 chr19:19648346 G/C cg03709012 chr19:19516395 GATAD2A 1.02 17.15 0.68 5.38e-48 Tonsillectomy; LIHC cis rs7224737 1.000 rs1869365 chr17:40293865 T/C cg02450064 chr17:40260053 DHX58 -0.3 -6.27 -0.32 1.07e-9 Fibrinogen levels; LIHC cis rs10420951 0.535 rs78061871 chr19:18566637 G/A cg10790698 chr19:18539756 SSBP4 -0.41 -5.81 -0.3 1.42e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs921968 0.643 rs500317 chr2:219432953 G/C cg17980119 chr2:219472607 PLCD4 0.34 5.81 0.3 1.43e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2153535 0.541 rs9379207 chr6:8458186 C/T cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs921968 0.541 rs3770214 chr2:219508988 C/T cg02985541 chr2:219472218 PLCD4 -0.42 -6.47 -0.33 3.35e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg26545112 chr7:97833388 LMTK2 -0.41 -6.09 -0.31 3.11e-9 Alcohol dependence; LIHC cis rs617791 0.678 rs551659 chr11:65749645 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 8.89 0.43 3.58e-17 Breast cancer; LIHC cis rs3741404 0.757 rs2282492 chr11:63918589 A/G cg04317338 chr11:64019027 PLCB3 0.49 6.76 0.34 5.88e-11 Platelet count; LIHC cis rs8067354 0.645 rs9899611 chr17:57832190 A/G cg02344993 chr17:57696989 CLTC 0.7 11.86 0.54 2.02e-27 Hemoglobin concentration; LIHC cis rs7917772 0.560 rs729023 chr10:104341887 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -8.04 -0.4 1.45e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4555082 1.000 rs7149013 chr14:105759840 T/C cg13114125 chr14:105738426 BRF1 -0.78 -10.02 -0.48 7.05e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.11 -0.36 7.03e-12 Diabetic kidney disease; LIHC cis rs17685 0.671 rs10274404 chr7:75706634 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.26 -0.32 1.14e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7552404 1.000 rs11161510 chr1:76210289 A/G cg22875332 chr1:76189707 ACADM -0.46 -6.68 -0.34 9.72e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9733 0.593 rs10888384 chr1:150574256 C/T cg13175981 chr1:150552382 MCL1 0.63 9.71 0.46 7.82e-20 Tonsillectomy; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC cis rs6912958 0.525 rs586771 chr6:88064971 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.63 0.53 1.49e-26 Monocyte percentage of white cells; LIHC cis rs3820068 0.603 rs6668726 chr1:15962614 G/A cg17385448 chr1:15911702 AGMAT 0.34 5.84 0.3 1.21e-8 Systolic blood pressure; LIHC cis rs6815814 0.898 rs6848423 chr4:38887933 C/T cg06935464 chr4:38784597 TLR10 0.44 6.79 0.34 5.02e-11 Breast cancer; LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs11628318 0.853 rs7155171 chr14:103031845 C/T cg01864069 chr14:103024347 NA -0.57 -9.5 -0.46 3.73e-19 Platelet count; LIHC cis rs9916302 0.904 rs4795355 chr17:37427382 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.46 -0.59 2.02e-33 Glomerular filtration rate (creatinine); LIHC cis rs1697938 0.875 rs323561 chr5:40871745 T/G cg01087697 chr5:40835557 RPL37 -0.49 -6.05 -0.31 3.76e-9 Multiple system atrophy; LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg12016809 chr21:47604291 C21orf56 -0.48 -7.47 -0.37 6.65e-13 Testicular germ cell tumor; LIHC trans rs7246657 0.943 rs10406177 chr19:37907947 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs6435862 0.500 rs12477063 chr2:215673664 C/T cg04530015 chr2:215796436 ABCA12 0.49 9.01 0.44 1.46e-17 Neuroblastoma (high-risk); LIHC cis rs7727544 0.709 rs272852 chr5:131688767 G/A cg07395648 chr5:131743802 NA -0.31 -6.56 -0.33 2.05e-10 Blood metabolite levels; LIHC cis rs9733 0.596 rs7538493 chr1:150655421 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Tonsillectomy; LIHC cis rs11676855 1.000 rs11676855 chr2:235900171 C/T cg14917874 chr2:235941519 SH3BP4 -0.54 -7.21 -0.36 3.57e-12 Dialysis-related mortality; LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs34172651 0.876 rs964782 chr16:24811740 T/C cg00339695 chr16:24857497 SLC5A11 0.55 8.3 0.41 2.52e-15 Intelligence (multi-trait analysis); LIHC cis rs3741404 0.825 rs7111753 chr11:63942189 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.96 16.31 0.66 1.18e-44 Platelet count; LIHC cis rs2652834 0.519 rs4075584 chr15:63340292 C/T cg05507819 chr15:63340323 TPM1 0.68 5.71 0.3 2.43e-8 HDL cholesterol; LIHC cis rs599083 0.569 rs685095 chr11:68170376 C/T cg16797656 chr11:68205561 LRP5 -0.5 -7.83 -0.39 6.38e-14 Bone mineral density (spine); LIHC cis rs9393692 0.905 rs6916289 chr6:26289122 A/T cg05868516 chr6:26286170 HIST1H4H 0.42 6.38 0.33 5.81e-10 Educational attainment; LIHC cis rs9457247 1.000 rs415842 chr6:167406681 G/A cg12798992 chr6:167411361 FGFR1OP 0.6 9.9 0.47 1.8e-20 Crohn's disease; LIHC cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg27297192 chr10:134578999 INPP5A 0.55 7.62 0.38 2.46e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9443189 0.570 rs7765254 chr6:76398143 T/C cg01950844 chr6:76311363 SENP6 0.85 9.82 0.47 3.22e-20 Prostate cancer; LIHC cis rs9658691 0.607 rs9658750 chr10:90766596 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.83 -6.16 -0.32 2.05e-9 Mosquito bite size; LIHC cis rs2439831 0.717 rs28495368 chr15:43895642 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.86 0.35 3.28e-11 Lung cancer in ever smokers; LIHC cis rs3809566 1.000 rs4775612 chr15:63332157 T/C cg05771511 chr15:63340396 TPM1 0.47 6.97 0.35 1.63e-11 Platelet count; LIHC cis rs4144743 0.528 rs12940207 chr17:45352194 G/T cg18085866 chr17:45331354 ITGB3 -0.65 -7.13 -0.36 5.86e-12 Body mass index; LIHC cis rs4727027 0.804 rs13231262 chr7:148886058 C/T cg23583168 chr7:148888333 NA -0.77 -10.63 -0.5 5.47e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs270601 0.770 rs61352298 chr5:131600589 G/C cg24060327 chr5:131705240 SLC22A5 -0.53 -6.94 -0.35 1.96e-11 Acylcarnitine levels; LIHC cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg24879335 chr3:133465180 TF 0.28 6.33 0.32 7.84e-10 Iron status biomarkers; LIHC cis rs11690935 0.569 rs62183770 chr2:172838117 C/G cg13550731 chr2:172543902 DYNC1I2 0.43 6.44 0.33 4.02e-10 Schizophrenia; LIHC cis rs11190604 1.000 rs35106985 chr10:102307542 T/C cg07080220 chr10:102295463 HIF1AN 0.51 7.08 0.36 8.28e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7582720 1.000 rs76890136 chr2:203850011 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2841277 0.708 rs4465542 chr14:105407798 A/G cg21017887 chr14:105400489 NA 0.65 12.49 0.56 9.46e-30 Rheumatoid arthritis; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg05342682 chr7:94953680 PON1 -0.36 -6.46 -0.33 3.67e-10 Paraoxonase activity; LIHC cis rs4319547 0.774 rs7954006 chr12:123131824 A/C cg05707623 chr12:122985044 ZCCHC8 0.5 6.79 0.34 5.11e-11 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09864156 chr10:70939728 SUPV3L1 0.38 6.66 0.34 1.12e-10 Cognitive function; LIHC cis rs7659604 0.728 rs3924987 chr4:122689784 G/T cg20573242 chr4:122745356 CCNA2 0.51 7.7 0.38 1.44e-13 Type 2 diabetes; LIHC cis rs10791097 0.694 rs7106973 chr11:130758113 G/A cg22079354 chr11:130786696 SNX19 0.42 5.99 0.31 5.23e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs826838 0.935 rs11169547 chr12:39185625 C/A cg13010199 chr12:38710504 ALG10B 0.5 6.02 0.31 4.6e-9 Heart rate; LIHC trans rs11098499 0.687 rs71610270 chr4:120287436 A/G cg25214090 chr10:38739885 LOC399744 0.49 7.77 0.39 9.01e-14 Corneal astigmatism; LIHC cis rs13392177 0.637 rs61041183 chr2:219056380 G/A cg00012203 chr2:219082015 ARPC2 0.77 11.32 0.52 1.9e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs35883536 0.933 rs1409419 chr1:101183396 T/C cg14515779 chr1:101123966 NA -0.67 -12.76 -0.57 9.49e-31 Monocyte count; LIHC cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.22 0.52 4.31e-25 Colorectal cancer; LIHC cis rs1476670 0.565 rs2428965 chr1:44502909 A/G cg00251536 chr1:45205438 KIF2C -0.48 -7.28 -0.37 2.26e-12 Eotaxin levels; LIHC cis rs798554 0.757 rs1182177 chr7:2874540 C/T cg13628971 chr7:2884303 GNA12 0.55 7.66 0.38 1.99e-13 Height; LIHC cis rs853679 0.513 rs9468296 chr6:28113730 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs4147929 0.553 rs4147936 chr19:1065197 G/C cg05372495 chr19:1063624 ABCA7 -0.42 -6.7 -0.34 8.43e-11 Alzheimer's disease (late onset); LIHC cis rs12497850 0.764 rs6784111 chr3:49178846 T/C cg07636037 chr3:49044803 WDR6 0.88 15.27 0.64 1.62e-40 Parkinson's disease; LIHC cis rs875971 0.545 rs1638724 chr7:66040481 A/G cg11764359 chr7:65958608 NA -0.62 -8.95 -0.44 2.34e-17 Aortic root size; LIHC cis rs2072499 0.966 rs2842857 chr1:156168736 T/C cg25208724 chr1:156163844 SLC25A44 0.95 16.48 0.67 2.64e-45 Testicular germ cell tumor; LIHC cis rs7091068 0.518 rs1409337 chr10:95439822 T/C cg20715218 chr10:95462985 C10orf4 0.57 8.27 0.41 3.08e-15 Urinary tract infection frequency; LIHC cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg10896456 chr17:42255109 ASB16;C17orf65 0.53 9.78 0.47 4.55e-20 Total body bone mineral density; LIHC cis rs6089584 0.888 rs2181590 chr20:60622843 T/C cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs9303280 0.651 rs59716545 chr17:38031857 T/G cg11212589 chr17:38028394 ZPBP2 0.35 7.16 0.36 4.87e-12 Self-reported allergy; LIHC cis rs483180 0.531 rs662243 chr1:120209564 A/C cg19096424 chr1:120255104 PHGDH 0.59 7.34 0.37 1.58e-12 Macular telangiectasia type 2; LIHC cis rs4478037 0.822 rs9826234 chr3:33123832 A/C cg27203090 chr3:33138513 GLB1;TMPPE -0.52 -6.52 -0.33 2.52e-10 Major depressive disorder; LIHC cis rs6449957 0.639 rs706711 chr5:67520226 G/A cg23036683 chr5:67512108 NA 0.54 7.84 0.39 5.77e-14 Cleft lip with or without cleft palate; LIHC cis rs943466 0.955 rs2894342 chr6:33774394 C/A cg25922239 chr6:33757077 LEMD2 -0.44 -6.07 -0.31 3.46e-9 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC trans rs2832077 0.943 rs4816336 chr21:30193519 C/T cg14791747 chr16:20752902 THUMPD1 0.47 6.29 0.32 9.64e-10 Cognitive test performance; LIHC cis rs1580019 0.563 rs896137 chr7:32579345 G/T cg14728415 chr7:32535168 LSM5;AVL9 0.42 6.06 0.31 3.52e-9 Cognitive ability; LIHC cis rs4423214 0.840 rs1792315 chr11:71165547 C/T cg05163923 chr11:71159392 DHCR7 -0.6 -8.04 -0.4 1.44e-14 Vitamin D levels; LIHC cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg21280719 chr6:42927975 GNMT -0.32 -7.0 -0.35 1.32e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1577917 1.000 rs12196037 chr6:86694631 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.66 -0.46 1.15e-19 Response to antipsychotic treatment; LIHC cis rs6430585 0.528 rs7606267 chr2:136668123 T/C cg15123519 chr2:136567270 LCT -0.36 -5.85 -0.3 1.14e-8 Corneal structure; LIHC cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg12310025 chr6:25882481 NA -0.58 -8.38 -0.41 1.43e-15 Blood metabolite levels; LIHC trans rs8113308 0.810 rs7254930 chr19:52451527 G/T cg14959425 chr7:20447707 ITGB8 -0.47 -6.11 -0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs8180040 0.654 rs6791062 chr3:47174343 T/A cg16586182 chr3:47516702 SCAP -0.48 -8.68 -0.42 1.65e-16 Colorectal cancer; LIHC cis rs11190604 1.000 rs3750627 chr10:102275642 G/T cg07080220 chr10:102295463 HIF1AN 0.56 8.05 0.4 1.37e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg02931644 chr1:25747376 RHCE -0.32 -6.9 -0.35 2.57e-11 Erythrocyte sedimentation rate; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg22903471 chr2:27725779 GCKR -0.52 -8.98 -0.44 1.79e-17 Total body bone mineral density; LIHC cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg21724239 chr8:58056113 NA 0.6 7.42 0.37 9.65e-13 Developmental language disorder (linguistic errors); LIHC cis rs7843479 0.932 rs68023663 chr8:21794379 T/C cg17168535 chr8:21777572 XPO7 0.45 7.41 0.37 1.02e-12 Mean corpuscular volume; LIHC cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg18404041 chr3:52824283 ITIH1 0.54 8.78 0.43 7.77e-17 Bipolar disorder; LIHC cis rs3806843 0.735 rs801168 chr5:140080298 A/G cg19875535 chr5:140030758 IK -0.41 -6.65 -0.34 1.18e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7412746 0.611 rs11803940 chr1:150685835 A/G cg18016565 chr1:150552671 MCL1 0.59 11.39 0.52 1.06e-25 Melanoma; LIHC cis rs7582720 1.000 rs72932554 chr2:203845828 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs916888 0.821 rs415430 chr17:44859144 C/T cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs11098499 1.000 rs28374891 chr4:120183550 G/A cg25214090 chr10:38739885 LOC399744 0.52 7.95 0.39 2.76e-14 Corneal astigmatism; LIHC cis rs11031096 0.782 rs10835684 chr11:4168308 G/T cg18678763 chr11:4115507 RRM1 -0.52 -7.92 -0.39 3.38e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9322817 0.691 rs2486135 chr6:105282263 C/T cg02098413 chr6:105308735 HACE1 0.45 8.41 0.41 1.16e-15 Thyroid stimulating hormone; LIHC cis rs2806561 0.664 rs4620508 chr1:23307438 C/T cg12483005 chr1:23474871 LUZP1 0.43 6.49 0.33 2.97e-10 Height; LIHC cis rs6089829 0.962 rs6062776 chr20:61663736 A/G cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs10461617 0.541 rs860581 chr5:56150537 A/G cg24531977 chr5:56204891 C5orf35 -0.65 -7.54 -0.38 4.3e-13 Type 2 diabetes; LIHC cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs2075371 1.000 rs2075372 chr7:133984432 C/T cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC cis rs4423214 0.959 rs12794668 chr11:71168715 C/T cg24826892 chr11:71159390 DHCR7 0.48 6.16 0.32 1.99e-9 Vitamin D levels; LIHC cis rs155076 0.938 rs485361 chr13:21845826 G/T cg11317459 chr13:21872234 NA -1.17 -13.06 -0.58 6.87e-32 White matter hyperintensity burden; LIHC cis rs3806843 0.735 rs801183 chr5:140091115 C/T cg19875535 chr5:140030758 IK 0.42 7.02 0.35 1.24e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg02951883 chr7:2050386 MAD1L1 -0.55 -8.91 -0.43 3.19e-17 Schizophrenia; LIHC cis rs3806843 0.741 rs2563293 chr5:140110536 T/C cg19875535 chr5:140030758 IK -0.41 -6.7 -0.34 8.83e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs7707921 0.752 rs34981833 chr5:81272732 T/C cg15871215 chr5:81402204 ATG10 -0.64 -6.34 -0.32 7.41e-10 Breast cancer; LIHC cis rs11931598 0.509 rs13140943 chr4:6977109 A/G cg19539972 chr4:7069911 GRPEL1 0.41 6.15 0.32 2.16e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs473651 0.935 rs540636 chr2:239358341 T/C cg08773314 chr2:239334832 ASB1 0.31 5.81 0.3 1.4e-8 Multiple system atrophy; LIHC cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg23758822 chr17:41437982 NA 0.93 17.8 0.69 1.27e-50 Menopause (age at onset); LIHC cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg19539972 chr4:7069911 GRPEL1 -0.61 -8.86 -0.43 4.61e-17 Monocyte percentage of white cells; LIHC cis rs17345786 0.861 rs74768235 chr3:101142821 T/C cg12386194 chr3:101231763 SENP7 0.59 7.62 0.38 2.57e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs1144333 1.000 rs1890967 chr1:76459544 T/C cg10523679 chr1:76189770 ACADM 0.45 6.43 0.33 4.19e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs12478296 1.000 rs57603292 chr2:243028537 G/A cg06360820 chr2:242988706 NA -0.94 -12.4 -0.56 2.09e-29 Obesity-related traits; LIHC cis rs765787 0.530 rs4514617 chr15:45535439 A/G cg25801113 chr15:45476975 SHF 0.36 6.1 0.31 2.92e-9 Uric acid levels; LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.63 -0.42 2.3e-16 Lymphocyte counts; LIHC cis rs970821 0.667 rs2891798 chr8:124744096 C/T cg00283535 chr8:124749564 ANXA13 0.42 7.67 0.38 1.75e-13 Breast cancer; LIHC cis rs611744 0.781 rs656406 chr8:109173843 G/A cg18478394 chr8:109455254 TTC35 0.4 6.79 0.34 4.92e-11 Dupuytren's disease; LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg22907277 chr7:1156413 C7orf50 0.54 8.34 0.41 1.89e-15 Longevity;Endometriosis; LIHC cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.53 -9.48 -0.46 4.49e-19 Bipolar disorder; LIHC cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg03517284 chr6:25882590 NA -0.64 -8.97 -0.44 1.95e-17 Blood metabolite levels; LIHC cis rs875971 0.964 rs6945032 chr7:65922486 C/T cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs9916302 0.904 rs11654018 chr17:37703740 C/T cg15445000 chr17:37608096 MED1 -0.38 -5.81 -0.3 1.45e-8 Glomerular filtration rate (creatinine); LIHC cis rs11888559 0.655 rs4328616 chr2:204007739 G/C cg24605529 chr2:203879461 NBEAL1 0.78 5.92 0.31 7.62e-9 Height; LIHC cis rs2072499 0.838 rs2758619 chr1:156162559 A/G cg25208724 chr1:156163844 SLC25A44 0.93 15.93 0.65 3.87e-43 Testicular germ cell tumor; LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg00280220 chr17:61926910 NA 0.43 6.88 0.35 2.83e-11 Prudent dietary pattern; LIHC cis rs9486719 1.000 rs11153058 chr6:97012746 C/T cg06623918 chr6:96969491 KIAA0776 -0.71 -7.26 -0.37 2.62e-12 Migraine;Coronary artery disease; LIHC cis rs17106184 1.000 rs72904709 chr1:51306002 A/G cg07174182 chr1:51127561 FAF1 -0.62 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC cis rs17826219 0.500 rs2874724 chr17:29072433 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Body mass index; LIHC cis rs6546550 0.935 rs13017134 chr2:70090579 C/G cg02498382 chr2:70120550 SNRNP27 -0.38 -6.34 -0.32 7.24e-10 Prevalent atrial fibrillation; LIHC cis rs2251381 0.750 rs8129616 chr21:30520085 C/T cg08807101 chr21:30365312 RNF160 -0.71 -9.74 -0.47 6.18e-20 Selective IgA deficiency; LIHC cis rs6952808 0.595 rs3800917 chr7:2167939 A/G cg04267008 chr7:1944627 MAD1L1 0.51 7.98 0.4 2.18e-14 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg21724239 chr8:58056113 NA 0.59 6.86 0.35 3.17e-11 Developmental language disorder (linguistic errors); LIHC cis rs1387259 0.570 rs12368659 chr12:48562299 C/A cg21466736 chr12:48725269 NA -0.63 -9.13 -0.44 6.16e-18 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg06873352 chr17:61820015 STRADA 0.72 12.38 0.56 2.38e-29 Prudent dietary pattern; LIHC trans rs7618501 1.000 rs34451146 chr3:49813013 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.81 15.13 0.63 5.93e-40 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.780 rs10013652 chr4:120292256 A/G cg09307838 chr4:120376055 NA 0.64 9.7 0.46 8.23e-20 Corneal astigmatism; LIHC trans rs6600671 1.000 rs1986111 chr1:121204788 C/T cg08727972 chr1:148025634 NBPF14 0.4 6.07 0.31 3.46e-9 Hip geometry; LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.59 9.01 0.44 1.44e-17 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08556938 chr17:58512855 NA 0.44 6.44 0.33 4.05e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11478273 chr8:128806682 PVT1 0.5 6.67 0.34 1.05e-10 Lung function (FEV1/FVC); LIHC trans rs17083533 0.661 rs76715387 chr6:121750190 C/G cg16423337 chr3:52828818 ITIH3 0.29 6.34 0.32 7.12e-10 Heart rate; LIHC cis rs1997103 0.911 rs6945663 chr7:55407011 C/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs16958440 0.708 rs62096465 chr18:44629624 C/T cg17192377 chr18:44677553 HDHD2 0.52 6.53 0.33 2.38e-10 Sitting height ratio; LIHC cis rs907683 0.584 rs12991025 chr2:220284779 C/T cg15015639 chr2:220282977 DES 0.36 8.83 0.43 5.53e-17 Resting heart rate; LIHC cis rs11098499 0.954 rs9993199 chr4:120392873 A/G cg09307838 chr4:120376055 NA -0.75 -12.39 -0.56 2.2e-29 Corneal astigmatism; LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg04025307 chr7:1156635 C7orf50 0.66 11.48 0.53 5.08e-26 Longevity;Endometriosis; LIHC trans rs9914544 0.545 rs2892016 chr17:18786776 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.75e-10 Educational attainment (years of education); LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.76 0.39 1e-13 Prudent dietary pattern; LIHC cis rs2066819 1.000 rs57279772 chr12:56698960 G/A cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs11588062 0.601 rs4660344 chr1:46805222 A/G cg15696662 chr1:46669221 C1orf190;POMGNT1 0.43 6.75 0.34 6.19e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs13392177 0.660 rs10932762 chr2:219076213 G/C cg00012203 chr2:219082015 ARPC2 -0.75 -11.24 -0.52 3.6e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs9399135 0.967 rs12527707 chr6:135324511 G/A cg24558204 chr6:135376177 HBS1L 0.4 6.67 0.34 1.04e-10 Red blood cell count; LIHC cis rs7572733 0.534 rs770662 chr2:198729283 T/C cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs2806561 1.000 rs2806558 chr1:23503456 T/C cg19743168 chr1:23544995 NA 0.43 8.25 0.41 3.47e-15 Height; LIHC cis rs28830936 1.000 rs11629485 chr15:41904569 C/T cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.91 -0.3 8.46e-9 Diastolic blood pressure; LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.52 -0.38 4.85e-13 Lymphocyte counts; LIHC cis rs4727027 0.933 rs12154382 chr7:148862284 C/T cg23583168 chr7:148888333 NA -0.74 -10.48 -0.49 1.83e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg11494091 chr17:61959527 GH2 0.44 8.14 0.4 7.19e-15 Prudent dietary pattern; LIHC cis rs992157 0.764 rs4672886 chr2:219185545 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.68 -9.58 -0.46 2.01e-19 Colorectal cancer; LIHC cis rs10744422 0.800 rs1696320 chr12:123269814 A/G cg18912006 chr12:123335444 HIP1R -0.52 -6.03 -0.31 4.17e-9 Schizophrenia; LIHC cis rs801193 0.935 rs2286683 chr7:66129843 G/A cg11764359 chr7:65958608 NA -0.71 -10.55 -0.5 1.05e-22 Aortic root size; LIHC cis rs950776 0.518 rs3813572 chr15:78832588 T/C cg22563815 chr15:78856949 CHRNA5 0.36 6.57 0.33 1.9e-10 Sudden cardiac arrest; LIHC cis rs7618501 1.000 rs9855505 chr3:49792158 T/G cg24110177 chr3:50126178 RBM5 0.42 6.47 0.33 3.43e-10 Intelligence (multi-trait analysis); LIHC cis rs7614311 0.731 rs73130534 chr3:63859813 A/G cg22134162 chr3:63841271 THOC7 -0.54 -6.19 -0.32 1.75e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs6582630 0.519 rs1851130 chr12:38507819 C/T cg26384229 chr12:38710491 ALG10B 0.68 9.6 0.46 1.74e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs7131987 0.650 rs10843382 chr12:29451721 G/A cg00204748 chr12:29376779 FAR2 0.39 7.24 0.36 3.03e-12 QT interval; LIHC cis rs6912958 0.712 rs6454638 chr6:88329427 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.5 8.76 0.43 9.07e-17 Monocyte percentage of white cells; LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.66e-17 Prudent dietary pattern; LIHC cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.57 8.59 0.42 3.16e-16 Schizophrenia; LIHC cis rs4474465 1.000 rs10899513 chr11:78172353 T/C cg27205649 chr11:78285834 NARS2 -0.38 -5.88 -0.3 9.86e-9 Alzheimer's disease (survival time); LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg21724239 chr8:58056113 NA 0.55 7.05 0.36 9.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs12594515 1.000 rs8026221 chr15:45987910 G/T cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.8e-12 Waist circumference;Weight; LIHC cis rs17152411 0.652 rs3845 chr10:126674093 T/C cg07906193 chr10:126599966 NA -0.31 -6.31 -0.32 8.84e-10 Height; LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs72781680 0.898 rs17509001 chr2:24021231 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg04267008 chr7:1944627 MAD1L1 -0.59 -9.21 -0.45 3.35e-18 Bipolar disorder and schizophrenia; LIHC cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg22800045 chr5:56110881 MAP3K1 0.68 8.71 0.43 1.35e-16 Initial pursuit acceleration; LIHC cis rs748404 0.697 rs501884 chr15:43553982 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.71 0.34 8.14e-11 Lung cancer; LIHC cis rs9309473 0.950 rs11689588 chr2:73773691 A/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.42 -0.33 4.43e-10 Metabolite levels; LIHC cis rs17376456 0.825 rs55724660 chr5:93276636 A/G cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs2404602 0.735 rs56246286 chr15:76690731 C/T cg03037974 chr15:76606532 NA -0.65 -11.6 -0.53 1.8e-26 Blood metabolite levels; LIHC cis rs7208859 0.673 rs423151 chr17:28952286 A/G cg13385521 chr17:29058706 SUZ12P 0.56 5.74 0.3 2.04e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs877282 0.891 rs11253355 chr10:768367 C/G cg22713356 chr15:30763199 NA 1.38 12.35 0.56 3.16e-29 Uric acid levels; LIHC cis rs10924970 0.625 rs10802624 chr1:235494971 A/G cg26050004 chr1:235667680 B3GALNT2 0.4 5.74 0.3 2.14e-8 Asthma; LIHC cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6951245 0.810 rs117800627 chr7:1081075 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.71 -5.91 -0.3 8.4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8050755 0.649 rs2516737 chr16:2101749 A/G cg04515572 chr16:2107413 TSC2 0.82 6.83 0.35 3.98e-11 Major depressive disorder; LIHC cis rs8084351 0.539 rs4638654 chr18:50640310 A/G cg24270629 chr18:50823537 DCC 0.42 6.24 0.32 1.3e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs11711311 0.911 rs34337798 chr3:113396704 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.4 6.71 0.34 8.17e-11 IgG glycosylation; LIHC cis rs12478296 0.901 rs73007142 chr2:243010852 T/C cg06360820 chr2:242988706 NA -0.95 -12.16 -0.55 1.59e-28 Obesity-related traits; LIHC cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg04025307 chr7:1156635 C7orf50 0.47 7.83 0.39 6.15e-14 Longevity;Endometriosis; LIHC cis rs10256972 0.933 rs35696159 chr7:1047194 A/G cg23978390 chr7:1156363 C7orf50 0.53 8.02 0.4 1.68e-14 Longevity;Endometriosis; LIHC cis rs6977660 0.714 rs12700077 chr7:19791607 A/G cg07541023 chr7:19748670 TWISTNB -0.49 -7.21 -0.36 3.65e-12 Thyroid stimulating hormone; LIHC cis rs9486719 1.000 rs12530462 chr6:97053514 C/T cg06623918 chr6:96969491 KIAA0776 -0.73 -7.23 -0.36 3.25e-12 Migraine;Coronary artery disease; LIHC cis rs74417235 0.639 rs7443642 chr5:154053450 A/G cg19735590 chr5:154026979 NA -0.48 -5.91 -0.3 8.18e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs2463822 1.000 rs12279819 chr11:62137245 G/A cg06239285 chr11:62104954 ASRGL1 -0.96 -7.04 -0.36 1.06e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs4925386 1.000 rs6089351 chr20:60916153 G/A cg03945807 chr20:60948434 NA -0.36 -6.44 -0.33 3.97e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7223966 1.000 rs11079511 chr17:61858537 C/G cg05941027 chr17:61774174 LIMD2 0.35 7.47 0.37 6.76e-13 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07024458 chr16:56390600 GNAO1 0.45 7.35 0.37 1.52e-12 Cognitive function; LIHC cis rs694739 1.000 rs646153 chr11:64089588 C/T cg23796481 chr11:64053134 BAD;GPR137 0.61 8.44 0.42 9.17e-16 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04339246 chr15:89876433 POLG -0.48 -6.91 -0.35 2.37e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs600626 0.636 rs11236517 chr11:75452721 T/C cg24262691 chr11:75473276 NA 0.39 5.88 0.3 9.79e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs6840360 0.533 rs13139327 chr4:152728590 A/C cg22705602 chr4:152727874 NA -0.4 -8.34 -0.41 1.83e-15 Intelligence (multi-trait analysis); LIHC cis rs10493773 0.577 rs17398175 chr1:86074710 A/G cg17807903 chr1:86174739 ZNHIT6 -0.48 -6.64 -0.34 1.27e-10 Urate levels in overweight individuals; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg00280220 chr17:61926910 NA -0.39 -6.3 -0.32 9.1e-10 Prudent dietary pattern; LIHC trans rs1814175 0.817 rs4084376 chr11:49831160 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3e-11 Height; LIHC cis rs2839186 0.872 rs13052233 chr21:47707284 G/T cg12016809 chr21:47604291 C21orf56 0.41 5.95 0.31 6.57e-9 Testicular germ cell tumor; LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs7582720 0.725 rs72934725 chr2:203725983 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.76 6.15 0.32 2.15e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7587476 1.000 rs2121285 chr2:215656168 C/G cg04004882 chr2:215674386 BARD1 -0.51 -6.79 -0.34 4.86e-11 Neuroblastoma; LIHC cis rs1008375 1.000 rs4698200 chr4:17657051 G/A cg16339924 chr4:17578868 LAP3 0.45 6.27 0.32 1.11e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4974559 0.895 rs57037487 chr4:1386652 A/G cg16405210 chr4:1374714 KIAA1530 -0.44 -5.82 -0.3 1.39e-8 Systolic blood pressure; LIHC cis rs477692 0.637 rs7098627 chr10:131315866 C/T cg05714579 chr10:131428358 MGMT 0.41 6.64 0.34 1.27e-10 Response to temozolomide; LIHC cis rs11626933 0.851 rs2282031 chr14:90730943 A/G cg04374321 chr14:90722782 PSMC1 0.52 8.41 0.41 1.09e-15 Gut microbiota (bacterial taxa); LIHC cis rs2404602 0.647 rs11072610 chr15:76930805 C/A cg23625390 chr15:77176239 SCAPER -0.53 -8.67 -0.42 1.73e-16 Blood metabolite levels; LIHC cis rs35883536 0.588 rs12568329 chr1:101104588 A/G cg14515779 chr1:101123966 NA 0.59 11.42 0.53 8.03e-26 Monocyte count; LIHC cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.96 0.31 6.31e-9 Bipolar disorder; LIHC cis rs4665809 1.000 rs4665309 chr2:26335502 T/C cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs61990749 0.511 rs7146020 chr14:78358319 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.38 6.2 0.32 1.64e-9 Fibroblast growth factor basic levels; LIHC cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg04317338 chr11:64019027 PLCB3 0.48 6.73 0.34 7.08e-11 Platelet count; LIHC cis rs5769765 0.773 rs138861 chr22:50202276 A/G cg02269571 chr22:50332266 NA -0.66 -8.72 -0.43 1.27e-16 Schizophrenia; LIHC cis rs2904967 0.568 rs531178 chr11:64852421 T/C cg19545356 chr11:64851426 ZFPL1;CDCA5 1.06 6.82 0.35 4.15e-11 Mean corpuscular volume; LIHC cis rs9303401 0.646 rs7217845 chr17:57236900 G/A cg12560992 chr17:57184187 TRIM37 0.53 7.23 0.36 3.18e-12 Cognitive test performance; LIHC cis rs7617480 0.648 rs9882443 chr3:48749064 G/A cg07636037 chr3:49044803 WDR6 0.71 8.04 0.4 1.52e-14 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs748404 0.560 rs1869258 chr15:43803621 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.44 7.39 0.37 1.12e-12 Lung cancer; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg13409248 chr3:40428643 ENTPD3 0.49 8.33 0.41 1.95e-15 Renal cell carcinoma; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05787120 chr3:50365854 TUSC2 0.46 6.46 0.33 3.52e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs679087 0.686 rs10843500 chr12:29918582 C/G cg14258853 chr12:29935411 TMTC1 0.37 6.17 0.32 1.91e-9 Schizophrenia; LIHC cis rs875971 0.660 rs10215132 chr7:66054406 C/A cg11764359 chr7:65958608 NA -0.72 -10.98 -0.51 3.23e-24 Aortic root size; LIHC cis rs61677309 1.000 rs67462512 chr11:118155336 G/C cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.77 0.57 8.09e-31 Alzheimer's disease; LIHC cis rs7103648 0.630 rs7934481 chr11:47883337 C/T cg20307385 chr11:47447363 PSMC3 0.97 14.7 0.62 3.06e-38 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs28595532 0.702 rs72670250 chr4:119337134 T/C cg21605333 chr4:119757512 SEC24D 1.0 8.21 0.41 4.45e-15 Cannabis dependence symptom count; LIHC cis rs7572733 0.515 rs1836234 chr2:198882873 T/G cg03934865 chr2:198174659 NA 0.43 6.2 0.32 1.62e-9 Dermatomyositis; LIHC cis rs7312933 0.531 rs1796380 chr12:42791543 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.56 -8.44 -0.42 9.35e-16 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs151997 0.962 rs27256 chr5:50190264 G/C cg06027927 chr5:50259733 NA 0.57 7.69 0.38 1.6e-13 Callous-unemotional behaviour; LIHC cis rs17384381 0.861 rs2300640 chr1:85823795 C/G cg16011679 chr1:85725395 C1orf52 0.84 8.67 0.42 1.74e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs12765878 1.000 rs7100920 chr10:105640978 A/G cg11005552 chr10:105648138 OBFC1 -0.39 -6.11 -0.31 2.72e-9 Coronary artery disease; LIHC cis rs9916302 0.706 rs9899069 chr17:37540772 A/G cg07936489 chr17:37558343 FBXL20 0.86 12.17 0.55 1.45e-28 Glomerular filtration rate (creatinine); LIHC cis rs712039 0.687 rs11656455 chr17:35771885 G/A cg16670864 chr17:35848621 DUSP14 0.34 5.73 0.3 2.2e-8 Tuberculosis; LIHC cis rs2404602 0.647 rs11629727 chr15:77009038 G/C cg03037974 chr15:76606532 NA -0.58 -9.79 -0.47 4.01e-20 Blood metabolite levels; LIHC cis rs9902453 0.935 rs9909093 chr17:28271207 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.99 0.6 1.73e-35 Coffee consumption (cups per day); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg22016770 chr5:42468779 GHR 0.43 6.12 0.31 2.53e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg11062466 chr8:58055876 NA 0.51 7.61 0.38 2.72e-13 Developmental language disorder (linguistic errors); LIHC cis rs11577318 0.853 rs7537477 chr1:26618829 C/T cg00852783 chr1:26633632 UBXN11 0.4 6.47 0.33 3.39e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7799006 0.527 rs2159045 chr7:2207401 T/C cg02951883 chr7:2050386 MAD1L1 -0.57 -8.68 -0.42 1.65e-16 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs138857 0.515 rs9616375 chr22:50310600 G/A cg09182678 chr22:50328711 NA -0.69 -7.62 -0.38 2.47e-13 Mean platelet volume; LIHC cis rs6519955 0.796 rs4072455 chr22:46422938 T/C cg00209037 chr22:46443395 NA -0.66 -8.05 -0.4 1.35e-14 Dupuytren's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25485084 chr12:118809325 TAOK3 0.42 6.39 0.33 5.54e-10 Pancreatic cancer; LIHC cis rs12048904 0.619 rs10875347 chr1:101333737 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 11.41 0.53 8.93e-26 Multiple sclerosis; LIHC cis rs5769765 0.954 rs910799 chr22:50278568 A/G cg02269571 chr22:50332266 NA 0.64 8.97 0.44 2.05e-17 Schizophrenia; LIHC cis rs6545883 0.929 rs778155 chr2:61647901 A/G cg14146966 chr2:61757674 XPO1 -0.44 -7.5 -0.38 5.7e-13 Tuberculosis; LIHC cis rs644799 0.710 rs3748253 chr11:95519506 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.76 13.29 0.58 8.77e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs13201877 0.591 rs3850213 chr6:137655458 A/T cg16624405 chr10:133607033 NA -0.43 -6.28 -0.32 1.03e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs72627123 0.531 rs3742806 chr14:74532523 A/C cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 5.78 0.3 1.69e-8 Morning vs. evening chronotype; LIHC cis rs4654899 1.000 rs7554770 chr1:21481361 A/T cg08539965 chr1:21396338 EIF4G3 0.33 5.79 0.3 1.63e-8 Superior frontal gyrus grey matter volume; LIHC cis rs818427 0.681 rs469523 chr5:112294680 A/G cg07820702 chr5:112228657 REEP5 0.4 6.2 0.32 1.62e-9 Total body bone mineral density; LIHC cis rs875971 0.862 rs6947339 chr7:65888470 T/C cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC cis rs10242455 0.571 rs45532337 chr7:99310319 A/G cg18809830 chr7:99032528 PTCD1 -0.83 -6.67 -0.34 1.05e-10 Blood metabolite levels; LIHC cis rs2531992 1.000 rs710893 chr16:4014964 A/G cg05927578 chr16:4029543 ADCY9 0.58 6.38 0.33 5.9e-10 Waist circumference; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09477006 chr4:6711267 MRFAP1L1 0.52 7.13 0.36 6.13e-12 Lung function (FEV1/FVC); LIHC cis rs35306767 0.855 rs61830900 chr10:871481 C/G cg20503657 chr10:835505 NA 1.34 13.9 0.6 3.84e-35 Eosinophil percentage of granulocytes; LIHC trans rs941408 1.000 rs1736179 chr19:2795516 T/A cg19676328 chr12:49525230 TUBA1B -0.46 -6.85 -0.35 3.54e-11 Total cholesterol levels; LIHC cis rs9814567 0.963 rs36006513 chr3:134291913 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.25 0.55 7.29e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2406342 0.528 rs75536638 chr18:74499060 G/T cg16472389 chr18:74514291 NA 0.45 6.22 0.32 1.43e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin); LIHC cis rs1403694 0.515 rs1648700 chr3:186449916 C/T cg12454167 chr3:186435060 KNG1 -0.31 -7.35 -0.37 1.46e-12 Blood protein levels; LIHC trans rs530081 0.659 rs500903 chr18:32693303 C/T cg26396443 chr14:99729005 BCL11B 0.34 6.12 0.31 2.53e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg20887711 chr4:1340912 KIAA1530 0.6 9.28 0.45 2.04e-18 Obesity-related traits; LIHC cis rs1799949 0.965 rs7223952 chr17:41194885 T/C cg25072359 chr17:41440525 NA 0.38 6.04 0.31 3.92e-9 Menopause (age at onset); LIHC cis rs2777491 0.574 rs11858812 chr15:41731550 G/A cg18705301 chr15:41695430 NDUFAF1 -1.23 -18.42 -0.71 3.99e-53 Ulcerative colitis; LIHC cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg18357526 chr6:26021779 HIST1H4A 0.58 8.01 0.4 1.85e-14 Blood metabolite levels; LIHC cis rs9902453 0.817 rs12051834 chr17:28192785 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.33 0.55 3.71e-29 Coffee consumption (cups per day); LIHC trans rs4650994 0.525 rs2493864 chr1:178545003 A/C cg05059571 chr16:84539110 KIAA1609 -0.44 -7.38 -0.37 1.18e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs6918586 0.658 rs198838 chr6:26113340 C/T cg18357526 chr6:26021779 HIST1H4A 0.57 8.54 0.42 4.61e-16 Schizophrenia; LIHC cis rs6598955 0.670 rs3795688 chr1:26560481 C/A cg00852783 chr1:26633632 UBXN11 0.48 8.07 0.4 1.22e-14 Obesity-related traits; LIHC cis rs4727027 0.737 rs10278971 chr7:148780659 A/T cg23583168 chr7:148888333 NA -0.68 -9.11 -0.44 7.15e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs921968 0.643 rs524902 chr2:219433357 A/C cg18887096 chr2:219472410 PLCD4 0.36 6.33 0.32 7.86e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3768617 0.510 rs2296292 chr1:183086757 A/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs7534824 0.625 rs17449022 chr1:101442367 T/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.4 0.37 1.08e-12 Refractive astigmatism; LIHC cis rs4819052 0.851 rs13052344 chr21:46676101 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.91 0.39 3.69e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2929278 0.589 rs11638972 chr15:44074691 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.37 -6.03 -0.31 4.34e-9 Schizophrenia; LIHC cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs6088590 1.000 rs910870 chr20:33292893 T/C cg24642439 chr20:33292090 TP53INP2 0.75 10.79 0.5 1.44e-23 Coronary artery disease; LIHC cis rs1775715 0.707 rs2808087 chr10:32146444 C/G cg14930904 chr10:32216787 ARHGAP12 0.35 5.99 0.31 5.46e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs933688 0.527 rs10038090 chr5:90582456 C/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.42 -5.82 -0.3 1.34e-8 Smoking behavior; LIHC cis rs2180341 0.889 rs2000909 chr6:127711173 G/A cg24812749 chr6:127587940 RNF146 0.84 13.15 0.58 3.15e-32 Breast cancer; LIHC cis rs3806843 0.868 rs2531345 chr5:140126781 T/G cg19875535 chr5:140030758 IK -0.35 -5.79 -0.3 1.57e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs16828019 0.777 rs115916606 chr1:41642700 C/G cg20697417 chr1:41786797 NA 0.35 6.59 0.34 1.66e-10 Intelligence (multi-trait analysis); LIHC cis rs2832191 0.791 rs2832202 chr21:30501342 G/A cg08807101 chr21:30365312 RNF160 -0.56 -8.74 -0.43 1.04e-16 Dental caries; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.45e-13 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC trans rs637571 0.522 rs538954 chr11:65756808 A/G cg17712092 chr4:129076599 LARP1B 0.74 13.06 0.58 6.84e-32 Eosinophil percentage of white cells; LIHC cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg03264133 chr6:25882463 NA -0.65 -8.09 -0.4 1.07e-14 Intelligence (multi-trait analysis); LIHC cis rs10823500 0.674 rs7089860 chr10:71992848 C/G cg04118878 chr10:71993077 PPA1 0.58 6.32 0.32 8.31e-10 Blood protein levels; LIHC cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg20607798 chr8:58055168 NA 0.49 6.17 0.32 1.93e-9 Developmental language disorder (linguistic errors); LIHC cis rs12594515 1.000 rs8031128 chr15:45988528 C/G cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.84e-19 Waist circumference;Weight; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg27189623 chr16:705930 WDR90 0.34 5.79 0.3 1.61e-8 Height; LIHC cis rs600806 0.778 rs2043059 chr1:109991009 C/A cg16275483 chr1:110013120 SYPL2 -0.47 -5.83 -0.3 1.27e-8 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg11062466 chr8:58055876 NA 0.5 6.31 0.32 8.66e-10 Developmental language disorder (linguistic errors); LIHC cis rs138880 0.505 rs56248708 chr22:50306969 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.87 -7.69 -0.38 1.62e-13 Schizophrenia; LIHC cis rs9911578 1.000 rs304299 chr17:56838472 C/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.69 -0.43 1.55e-16 Intelligence (multi-trait analysis); LIHC cis rs9733 0.744 rs11204725 chr1:150742700 T/C cg18016565 chr1:150552671 MCL1 -0.49 -9.43 -0.45 6.5e-19 Tonsillectomy; LIHC cis rs77741769 0.553 rs12372231 chr12:121351729 T/A cg02419362 chr12:121203948 SPPL3 0.33 5.83 0.3 1.28e-8 Mean corpuscular volume; LIHC cis rs9896052 0.649 rs6501798 chr17:73444647 C/T cg25649188 chr17:73499917 CASKIN2 0.44 7.03 0.36 1.12e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs4970988 0.501 rs11204713 chr1:150694623 T/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Urate levels; LIHC cis rs2153535 0.580 rs4960421 chr6:8459292 C/T cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs57590327 0.503 rs6802480 chr3:81906671 G/A cg07356753 chr3:81810745 GBE1 -0.52 -7.88 -0.39 4.46e-14 Extraversion; LIHC cis rs3741404 0.609 rs635139 chr11:63872210 A/G cg05016508 chr11:63871570 FLRT1;MACROD1 0.42 6.68 0.34 9.97e-11 Platelet count; LIHC trans rs57221529 0.766 rs4081847 chr5:574072 C/T cg25482853 chr8:67687455 SGK3 0.62 6.25 0.32 1.22e-9 Lung disease severity in cystic fibrosis; LIHC cis rs9918079 0.560 rs13147590 chr4:15621188 A/G cg16509355 chr4:15471240 CC2D2A 0.43 6.68 0.34 9.44e-11 Obesity-related traits; LIHC cis rs55665837 1.000 rs12792120 chr11:14469443 G/T cg19336497 chr11:14380999 RRAS2 -0.45 -8.3 -0.41 2.41e-15 Vitamin D levels; LIHC cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg12463550 chr7:65579703 CRCP 0.66 6.99 0.35 1.49e-11 Diabetic kidney disease; LIHC cis rs9811920 0.609 rs7636447 chr3:99612677 G/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs950776 0.518 rs12910100 chr15:78822667 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs11690935 0.959 rs12692970 chr2:172594197 T/C cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.86 -0.69 7.5400000000000006e-51 Schizophrenia; LIHC cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6450176 0.564 rs391470 chr5:53332338 A/G ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.5 -0.59 1.4e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1144333 0.655 rs968018 chr1:76395662 G/A cg22875332 chr1:76189707 ACADM 0.42 6.29 0.32 9.69e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs7635838 0.855 rs9816564 chr3:11475297 T/C cg00170343 chr3:11313890 ATG7 0.42 6.61 0.34 1.45e-10 HDL cholesterol; LIHC cis rs7091068 0.518 rs4144098 chr10:95432600 C/T cg20715218 chr10:95462985 C10orf4 0.53 7.65 0.38 2.05e-13 Urinary tract infection frequency; LIHC cis rs1577917 0.917 rs4098044 chr6:86462066 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.53 -0.42 4.67e-16 Response to antipsychotic treatment; LIHC cis rs919433 0.783 rs805497 chr2:198222548 A/T cg03934865 chr2:198174659 NA 0.54 8.54 0.42 4.61e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1371867 0.875 rs1788173 chr8:101330939 A/G cg06002616 chr8:101225028 SPAG1 0.34 5.96 0.31 6.28e-9 Atrioventricular conduction; LIHC cis rs2836950 0.565 rs2836943 chr21:40592611 C/T cg17971929 chr21:40555470 PSMG1 -0.39 -5.81 -0.3 1.45e-8 Menarche (age at onset); LIHC cis rs6835098 0.962 rs10014010 chr4:174083230 C/T cg08422745 chr4:174089978 GALNT7 -0.32 -5.71 -0.3 2.43e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs8114671 0.527 rs2295352 chr20:33320055 C/G cg07148914 chr20:33460835 GGT7 -0.58 -8.62 -0.42 2.58e-16 Height; LIHC cis rs921968 0.541 rs17462853 chr2:219345637 T/G cg02176678 chr2:219576539 TTLL4 -0.55 -7.66 -0.38 1.88e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs9486715 1.000 rs6905568 chr6:97066382 T/C cg06623918 chr6:96969491 KIAA0776 -0.84 -13.77 -0.6 1.21e-34 Headache; LIHC cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg03264133 chr6:25882463 NA -1.04 -12.95 -0.57 1.75e-31 Intelligence (multi-trait analysis); LIHC trans rs359466 0.720 rs12187599 chr5:173272518 C/T cg22556143 chr10:134061604 STK32C -0.4 -6.11 -0.31 2.79e-9 QRS complex (Sokolow-Lyon); LIHC cis rs2576037 0.526 rs2510444 chr18:44376849 G/T cg19077165 chr18:44547161 KATNAL2 -0.41 -6.38 -0.33 5.67e-10 Personality dimensions; LIHC cis rs2075371 1.000 rs2544221 chr7:133993014 G/C cg20476274 chr7:133979776 SLC35B4 0.73 11.85 0.54 2.24e-27 Mean platelet volume; LIHC cis rs1620921 0.505 rs4709467 chr6:161203079 G/A cg01280913 chr6:161186852 NA -0.29 -5.75 -0.3 2e-8 Lipoprotein (a) - cholesterol levels; LIHC cis rs597539 0.617 rs686348 chr11:68636996 A/G cg04772025 chr11:68637568 NA 0.46 6.22 0.32 1.44e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7296418 0.961 rs1727307 chr12:123575742 A/G cg00376283 chr12:123451042 ABCB9 0.72 12.54 0.56 6.36e-30 Platelet count; LIHC cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg13607699 chr17:42295918 UBTF 0.45 7.26 0.37 2.59e-12 Total body bone mineral density; LIHC cis rs7582180 0.629 rs11694642 chr2:100957813 A/G cg14675211 chr2:100938903 LONRF2 0.54 8.56 0.42 3.86e-16 Intelligence (multi-trait analysis); LIHC cis rs4474465 1.000 rs10899521 chr11:78184560 T/A cg02023728 chr11:77925099 USP35 0.33 5.97 0.31 6.09e-9 Alzheimer's disease (survival time); LIHC cis rs875971 0.522 rs1880556 chr7:65432544 T/C cg11764359 chr7:65958608 NA 0.7 9.5 0.46 3.82e-19 Aortic root size; LIHC cis rs2180341 1.000 rs9285460 chr6:127640190 A/G cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs1577917 0.655 rs2842600 chr6:86325632 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.15 -0.32 2.22e-9 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs9406165 chr6:8488837 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs921968 0.643 rs586374 chr2:219383003 A/C cg02985541 chr2:219472218 PLCD4 0.45 8.71 0.43 1.33e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg00149659 chr3:10157352 C3orf10 0.68 6.93 0.35 2.11e-11 Alzheimer's disease; LIHC cis rs763014 0.932 rs2269559 chr16:682297 T/C cg27189623 chr16:705930 WDR90 0.42 6.95 0.35 1.85e-11 Height; LIHC cis rs950169 0.887 rs62029593 chr15:84955180 A/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.5 0.42 5.84e-16 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08448040 chr3:13521693 HDAC11 0.44 6.28 0.32 1.01e-9 Pancreatic cancer; LIHC trans rs1552244 0.572 rs67439440 chr3:10169503 C/T cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs34172651 0.517 rs2547040 chr16:24736408 G/C cg00339695 chr16:24857497 SLC5A11 -0.69 -10.29 -0.49 8.01e-22 Intelligence (multi-trait analysis); LIHC cis rs1997103 1.000 rs9649857 chr7:55411777 C/T cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs10751667 0.666 rs4072741 chr11:976565 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.35e-21 Alzheimer's disease (late onset); LIHC cis rs208520 0.690 rs12213575 chr6:66735989 A/G cg07460842 chr6:66804631 NA 0.78 9.08 0.44 8.77e-18 Exhaled nitric oxide output; LIHC cis rs9916302 0.904 rs7501488 chr17:37576417 T/G cg03013999 chr17:37608204 MED1 0.36 5.9 0.3 8.71e-9 Glomerular filtration rate (creatinine); LIHC cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg13395646 chr4:1353034 KIAA1530 -0.63 -8.98 -0.44 1.79e-17 Obesity-related traits; LIHC cis rs739401 0.572 rs12276060 chr11:3015572 A/T cg08508325 chr11:3079039 CARS -0.3 -6.58 -0.34 1.82e-10 Longevity; LIHC cis rs765787 0.530 rs28526629 chr15:45540462 C/T cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.96 -0.31 6.34e-9 Uric acid levels; LIHC cis rs55823223 0.564 rs1463485 chr17:73851791 C/G cg19302996 chr17:73780495 UNK -0.54 -6.65 -0.34 1.14e-10 Psoriasis; LIHC cis rs3008870 0.755 rs3929738 chr1:67397865 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.77 0.5 1.73e-23 Lymphocyte percentage of white cells; LIHC cis rs7131987 0.621 rs3782506 chr12:29445422 A/C cg16970926 chr12:29381810 FAR2 -0.28 -5.89 -0.3 9.12e-9 QT interval; LIHC cis rs911555 0.504 rs61995761 chr14:104075712 T/C cg24130564 chr14:104152367 KLC1 -0.65 -12.09 -0.55 2.98e-28 Intelligence (multi-trait analysis); LIHC trans rs2243480 0.901 rs313808 chr7:65499873 T/G cg10756647 chr7:56101905 PSPH 1.09 13.55 0.59 9.11e-34 Diabetic kidney disease; LIHC cis rs8180040 0.620 rs17784127 chr3:47061700 T/C cg27129171 chr3:47204927 SETD2 -0.54 -9.08 -0.44 8.92e-18 Colorectal cancer; LIHC cis rs9858542 0.953 rs11711485 chr3:49491983 G/T cg03060546 chr3:49711283 APEH -0.5 -6.84 -0.35 3.57e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6570726 0.935 rs1883406 chr6:145823205 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088580 0.505 rs6141503 chr20:33274469 G/A cg07148914 chr20:33460835 GGT7 -0.49 -6.89 -0.35 2.63e-11 Glomerular filtration rate (creatinine); LIHC cis rs2304069 0.913 rs9324637 chr5:149390947 T/C cg12661370 chr5:149340060 SLC26A2 0.5 6.08 0.31 3.23e-9 HIV-1 control; LIHC cis rs7044106 0.762 rs3904197 chr9:123480378 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 7.42 0.37 9.58e-13 Hip circumference adjusted for BMI; LIHC cis rs3772130 0.527 rs2141614 chr3:121590173 G/A cg20356878 chr3:121714668 ILDR1 0.36 6.14 0.31 2.32e-9 Cognitive performance; LIHC cis rs11690935 0.959 rs10497374 chr2:172640623 A/G cg13550731 chr2:172543902 DYNC1I2 -0.94 -18.94 -0.72 3.09e-55 Schizophrenia; LIHC cis rs58688157 0.705 rs12419720 chr11:598205 C/G cg16486109 chr11:613632 IRF7 0.58 6.25 0.32 1.21e-9 Systemic lupus erythematosus; LIHC cis rs644799 0.965 rs598876 chr11:95560853 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1448094 0.549 rs12308898 chr12:86233678 G/A cg02569458 chr12:86230093 RASSF9 0.49 6.52 0.33 2.48e-10 Major depressive disorder; LIHC cis rs4834770 0.685 rs4496567 chr4:120175625 A/T cg09307838 chr4:120376055 NA 0.41 5.85 0.3 1.17e-8 Blood protein levels; LIHC cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg24531977 chr5:56204891 C5orf35 0.67 9.75 0.47 5.51e-20 Initial pursuit acceleration; LIHC cis rs7927592 0.956 rs2155730 chr11:68329474 T/C cg01657329 chr11:68192670 LRP5 -0.48 -6.33 -0.32 7.61e-10 Total body bone mineral density; LIHC cis rs68170813 0.559 rs7794965 chr7:106826439 A/G cg02696742 chr7:106810147 HBP1 0.53 6.18 0.32 1.82e-9 Coronary artery disease; LIHC cis rs116095464 0.614 rs56299325 chr5:220594 C/T cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs1552244 0.706 rs279545 chr3:9972493 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.53 -8.67 -0.42 1.8e-16 Alzheimer's disease; LIHC cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg09222892 chr1:25734099 RHCE 0.48 8.89 0.43 3.55e-17 Erythrocyte sedimentation rate; LIHC cis rs2228479 0.618 rs17233623 chr16:89811209 C/T cg06558623 chr16:89946397 TCF25 0.86 11.92 0.54 1.23e-27 Skin colour saturation; LIHC cis rs1371867 0.846 rs1788191 chr8:101260844 C/T cg06636551 chr8:101224915 SPAG1 0.51 9.64 0.46 1.26e-19 Atrioventricular conduction; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg08677398 chr8:58056175 NA 0.41 6.33 0.32 7.6e-10 Developmental language disorder (linguistic errors); LIHC cis rs6912958 0.630 rs4707377 chr6:88280332 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg16145915 chr7:1198662 ZFAND2A -0.38 -9.59 -0.46 1.94e-19 Longevity;Endometriosis; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC trans rs10506458 0.915 rs17763441 chr12:63418335 T/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.73 -10.57 -0.5 9.05e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs2228479 0.850 rs2238527 chr16:89840708 C/A cg06558623 chr16:89946397 TCF25 0.84 11.74 0.54 5.79e-27 Skin colour saturation; LIHC trans rs11098499 0.779 rs7356491 chr4:120381974 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.71 0.46 7.58e-20 Corneal astigmatism; LIHC cis rs7635838 0.827 rs9848170 chr3:11495983 G/C cg00170343 chr3:11313890 ATG7 0.4 6.17 0.32 1.94e-9 HDL cholesterol; LIHC cis rs875971 0.862 rs4718319 chr7:65652784 C/A cg18876405 chr7:65276391 NA -0.36 -6.37 -0.33 5.93e-10 Aortic root size; LIHC cis rs2386661 0.693 rs56226546 chr10:5659929 G/A cg17085576 chr10:5658249 NA -0.36 -6.44 -0.33 4.05e-10 Breast cancer; LIHC cis rs600806 0.778 rs10857787 chr1:110010289 C/T cg16275483 chr1:110013120 SYPL2 -0.49 -6.27 -0.32 1.11e-9 Intelligence (multi-trait analysis); LIHC cis rs3741151 1.000 rs60924672 chr11:73098724 A/C cg17517138 chr11:73019481 ARHGEF17 0.83 5.84 0.3 1.23e-8 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs4727027 0.865 rs12154368 chr7:148862041 C/T cg23583168 chr7:148888333 NA -0.74 -10.48 -0.49 1.83e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6582630 0.615 rs12821226 chr12:38546406 C/T cg26384229 chr12:38710491 ALG10B -0.49 -6.79 -0.34 4.84e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs6545883 0.826 rs2694617 chr2:61537214 G/A cg14146966 chr2:61757674 XPO1 -0.43 -7.33 -0.37 1.7e-12 Tuberculosis; LIHC cis rs2832191 0.671 rs2832213 chr21:30512914 A/G cg24692254 chr21:30365293 RNF160 -0.43 -6.7 -0.34 8.42e-11 Dental caries; LIHC trans rs875971 0.545 rs316316 chr7:65614257 C/T cg26939375 chr7:64535504 NA -0.41 -6.41 -0.33 4.96e-10 Aortic root size; LIHC trans rs61931739 0.517 rs10844738 chr12:34059503 T/A cg26384229 chr12:38710491 ALG10B 0.44 6.24 0.32 1.32e-9 Morning vs. evening chronotype; LIHC cis rs3099143 1.000 rs111908804 chr15:77123773 C/G cg21673338 chr15:77095150 SCAPER -0.52 -6.99 -0.35 1.49e-11 Recalcitrant atopic dermatitis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04600792 chr7:29256702 CHN2 0.37 6.07 0.31 3.45e-9 Cognitive function; LIHC cis rs2228479 0.850 rs11646766 chr16:89838578 A/T cg04013166 chr16:89971882 TCF25 0.54 6.81 0.35 4.53e-11 Skin colour saturation; LIHC cis rs74417235 0.684 rs13186731 chr5:154056002 C/T cg08754654 chr5:154026448 NA 0.32 6.99 0.35 1.45e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs4407350 0.870 rs135627 chr22:44906402 A/G cg11695653 chr22:44894386 LDOC1L -0.35 -5.97 -0.31 6.04e-9 Intelligence (multi-trait analysis); LIHC cis rs6088590 1.000 rs6120747 chr20:33449769 T/C cg06115741 chr20:33292138 TP53INP2 0.59 7.98 0.4 2.31e-14 Coronary artery disease; LIHC cis rs7589728 0.563 rs2292868 chr2:88475047 A/G cg04511125 chr2:88470314 THNSL2 -0.98 -10.01 -0.48 7.59e-21 Plasma clusterin levels; LIHC cis rs600806 0.778 rs11101961 chr1:110008813 T/C cg16275483 chr1:110013120 SYPL2 -0.49 -6.15 -0.32 2.16e-9 Intelligence (multi-trait analysis); LIHC cis rs919433 0.929 rs7592511 chr2:198177974 A/G cg03934865 chr2:198174659 NA -0.6 -9.67 -0.46 1.04e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2841277 0.708 rs9671643 chr14:105408030 A/G cg15352829 chr14:105391018 PLD4 -0.43 -9.2 -0.45 3.59e-18 Rheumatoid arthritis; LIHC cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs4246666 chr3:40407670 C/T cg09455208 chr3:40491958 NA 0.33 6.55 0.33 2.06e-10 Renal cell carcinoma; LIHC cis rs870825 0.929 rs72689261 chr4:185590897 C/A cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs11711311 1.000 rs7633832 chr3:113472292 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.96 -0.35 1.72e-11 IgG glycosylation; LIHC cis rs34779708 0.931 rs7079498 chr10:35375344 C/T cg03585969 chr10:35415529 CREM 0.87 13.13 0.58 3.59e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10197940 0.545 rs2444267 chr2:152308611 T/G cg06191203 chr2:152266755 RIF1 -0.42 -7.21 -0.36 3.58e-12 Lung cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19909895 chr3:128368930 RPN1 0.44 6.4 0.33 5.01e-10 Cognitive function; LIHC cis rs7520050 0.581 rs3855959 chr1:46633874 C/T cg24542714 chr1:46669345 POMGNT1;C1orf190 0.44 7.23 0.36 3.11e-12 Red blood cell count;Reticulocyte count; LIHC cis rs7197653 0.586 rs55856208 chr16:68324210 A/T cg05110241 chr16:68378359 PRMT7 -0.91 -9.38 -0.45 9.4e-19 Magnesium levels; LIHC trans rs7618501 1.000 rs2271960 chr3:49878078 A/G cg21582582 chr3:182698605 DCUN1D1 0.53 7.15 0.36 5.17e-12 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.41 0.52 9.38e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs172166 0.694 rs1631552 chr6:28089699 C/A cg23485639 chr6:28045615 ZNF165 0.41 6.38 0.33 5.68e-10 Cardiac Troponin-T levels; LIHC trans rs2302464 1.000 rs57326588 chr4:15725436 G/C cg17675199 chr6:35436792 RPL10A -0.4 -6.42 -0.33 4.56e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs34779708 0.966 rs2126984 chr10:35410291 A/G cg04310649 chr10:35416472 CREM -0.42 -5.8 -0.3 1.48e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs921968 0.643 rs10187066 chr2:219514759 A/G cg18887096 chr2:219472410 PLCD4 0.4 6.94 0.35 1.95e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21956150 chr19:1438388 RPS15 -0.35 -6.1 -0.31 2.8e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg12492359 chr2:203242268 BMPR2 0.44 6.13 0.31 2.42e-9 Migraine with aura; LIHC cis rs1005277 0.541 rs2505193 chr10:38394638 G/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7129220 0.588 rs61878625 chr11:10123136 T/C cg01453529 chr11:10209919 SBF2 -0.38 -6.8 -0.34 4.82e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs34779708 0.966 rs1057108 chr10:35484949 T/G cg03585969 chr10:35415529 CREM 0.84 12.6 0.56 3.53e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg11890956 chr21:40555474 PSMG1 1.07 16.09 0.66 8.9e-44 Cognitive function; LIHC cis rs7918232 0.941 rs10829195 chr10:27431564 G/A cg14442939 chr10:27389572 ANKRD26 0.72 7.07 0.36 8.65e-12 Breast cancer; LIHC cis rs9467773 0.901 rs1407045 chr6:26476155 A/G cg11502198 chr6:26597334 ABT1 0.41 5.74 0.3 2.12e-8 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.748 rs2748484 chr6:146333653 C/T cg05347473 chr6:146136440 FBXO30 0.35 5.73 0.3 2.19e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs3857067 1.000 rs3846291 chr4:95026735 A/G cg11021082 chr4:95130006 SMARCAD1 -0.4 -7.1 -0.36 7.3e-12 QT interval; LIHC cis rs7927592 0.956 rs7116899 chr11:68385535 G/T cg16797656 chr11:68205561 LRP5 0.5 7.83 0.39 6.08e-14 Total body bone mineral density; LIHC trans rs561341 0.883 rs4795661 chr17:30201774 T/A cg20587970 chr11:113659929 NA 0.72 8.17 0.4 6.16e-15 Hip circumference adjusted for BMI; LIHC cis rs34779708 0.733 rs3936502 chr10:35549218 C/T cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.77 -0.3 1.79e-8 Total body bone mineral density; LIHC cis rs2180341 1.000 rs2144743 chr6:127633810 A/T cg27446573 chr6:127587934 RNF146 1.03 16.06 0.66 1.17e-43 Breast cancer; LIHC cis rs1580019 0.922 rs766658 chr7:32499391 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.78 11.95 0.54 9.69e-28 Cognitive ability; LIHC trans rs11098499 0.866 rs6824111 chr4:120285968 T/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs77106637 0.585 rs10898870 chr11:72456218 A/C cg03713592 chr11:72463424 ARAP1 0.57 6.07 0.31 3.36e-9 Type 2 diabetes; LIHC cis rs6456156 0.586 rs1358883 chr6:167467433 C/G cg23791538 chr6:167370224 RNASET2 0.49 7.96 0.4 2.5e-14 Primary biliary cholangitis; LIHC trans rs62103177 0.673 rs55852342 chr18:77594109 G/C cg05926928 chr17:57297772 GDPD1 0.55 7.11 0.36 6.63e-12 Opioid sensitivity; LIHC trans rs7618501 1.000 rs3811696 chr3:49761605 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.846 rs2492856 chr6:146323928 A/G cg23711669 chr6:146136114 FBXO30 0.6 10.51 0.49 1.45e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg11764359 chr7:65958608 NA -0.55 -5.93 -0.31 7.52e-9 Diabetic kidney disease; LIHC cis rs9911578 0.835 rs1990008 chr17:56459408 C/G cg05425664 chr17:57184151 TRIM37 0.56 8.08 0.4 1.1e-14 Intelligence (multi-trait analysis); LIHC cis rs11971779 0.618 rs3778931 chr7:139102490 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs2839186 0.867 rs13050387 chr21:47701423 C/T cg00612595 chr21:47717864 NA -0.36 -5.86 -0.3 1.1e-8 Testicular germ cell tumor; LIHC cis rs2204008 0.905 rs8189449 chr12:38437377 C/A cg26384229 chr12:38710491 ALG10B 0.58 8.26 0.41 3.26e-15 Bladder cancer; LIHC trans rs1814175 0.645 rs28839231 chr11:50044292 G/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg25072359 chr17:41440525 NA 0.38 6.06 0.31 3.67e-9 Menopause (age at onset); LIHC cis rs6964587 1.000 rs3753107 chr7:91629151 C/T cg17063962 chr7:91808500 NA -1.03 -20.85 -0.75 7.21e-63 Breast cancer; LIHC cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg10802521 chr3:52805072 NEK4 -0.45 -7.73 -0.39 1.2e-13 Bipolar disorder; LIHC cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg13047869 chr3:10149882 C3orf24 0.53 6.7 0.34 8.73e-11 Alzheimer's disease; LIHC cis rs344364 0.636 rs344363 chr16:1972548 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.65 -8.03 -0.4 1.56e-14 Glomerular filtration rate in chronic kidney disease; LIHC cis rs8068544 0.818 rs8079958 chr17:40155467 C/T cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.43 -10.22 -0.48 1.44e-21 Reticulocyte fraction of red cells;Reticulocyte count; LIHC cis rs1348850 0.789 rs2197611 chr2:178369036 G/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.89 14.26 0.61 1.56e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs243505 0.733 rs9987055 chr7:148501758 G/A cg09806900 chr7:148480153 CUL1 0.43 6.37 0.33 5.99e-10 Inflammatory bowel disease;Crohn's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09051904 chr22:36635583 APOL2 0.45 6.15 0.32 2.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7408868 0.764 rs62113791 chr19:15277009 C/T cg09752223 chr19:15281200 NOTCH3 -0.37 -5.86 -0.3 1.07e-8 Pulse pressure; LIHC trans rs10506458 0.834 rs55966529 chr12:63384114 A/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.54 -0.5 1.11e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs11958404 1.000 rs56175756 chr5:157391080 T/C cg05962755 chr5:157440814 NA 1.06 11.58 0.53 2.25e-26 IgG glycosylation; LIHC cis rs881375 0.967 rs10739580 chr9:123695282 C/T cg14580859 chr9:123691850 NA 0.39 6.96 0.35 1.73e-11 Rheumatoid arthritis; LIHC cis rs10420951 0.617 rs79257623 chr19:18563714 G/A cg10790698 chr19:18539756 SSBP4 -0.42 -6.03 -0.31 4.15e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17270561 0.562 rs12199626 chr6:26013604 G/A cg16482183 chr6:26056742 HIST1H1C 0.84 10.9 0.51 5.92e-24 Iron status biomarkers; LIHC cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg06238570 chr21:40685208 BRWD1 0.58 6.86 0.35 3.34e-11 Cognitive function; LIHC trans rs7246657 1.000 rs7246657 chr19:37747108 C/T cg10208301 chr11:6592745 DNHD1 -0.45 -6.39 -0.33 5.43e-10 Coronary artery calcification; LIHC cis rs7107174 1.000 rs10899489 chr11:78095373 G/T cg02023728 chr11:77925099 USP35 0.41 7.5 0.38 5.68e-13 Testicular germ cell tumor; LIHC cis rs1355223 0.583 rs2956074 chr11:34864880 T/C cg11058730 chr11:34937778 PDHX;APIP 0.77 13.93 0.6 2.94e-35 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs17685 0.753 rs10233282 chr7:75790081 C/T cg16684958 chr7:75615977 POR 0.52 8.53 0.42 4.68e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67478160 0.643 rs2024667 chr14:104211529 T/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.85 0.57 4.09e-31 Schizophrenia; LIHC cis rs6062302 0.548 rs4809310 chr20:62228745 G/A cg16989086 chr20:62203971 PRIC285 0.57 8.2 0.41 5.08e-15 Glioblastoma; LIHC cis rs74233809 1.000 rs76752100 chr10:104794086 G/T cg03493300 chr10:104813866 CNNM2 0.47 6.38 0.33 5.75e-10 Birth weight; LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg05025164 chr4:1340916 KIAA1530 0.53 8.05 0.4 1.39e-14 Obesity-related traits; LIHC cis rs11971779 0.680 rs7779900 chr7:139082987 G/T cg07862535 chr7:139043722 LUC7L2 0.59 10.2 0.48 1.73e-21 Diisocyanate-induced asthma; LIHC cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg05025164 chr4:1340916 KIAA1530 0.8 12.77 0.57 8.46e-31 Longevity; LIHC cis rs77741769 0.571 rs73415720 chr12:121344515 T/C cg02419362 chr12:121203948 SPPL3 0.35 6.03 0.31 4.36e-9 Mean corpuscular volume; LIHC cis rs7786877 0.723 rs10487157 chr7:100214487 C/G cg00334542 chr7:100209784 MOSPD3 -0.7 -7.68 -0.38 1.65e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs950169 0.810 rs2879976 chr15:85109578 G/A cg17507749 chr15:85114479 UBE2QP1 0.73 8.42 0.41 1.02e-15 Schizophrenia; LIHC cis rs600806 0.850 rs1343465 chr1:109937426 T/C cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.816 rs56271597 chr3:10042790 C/T cg08888203 chr3:10149979 C3orf24 0.47 6.0 0.31 4.97e-9 Alzheimer's disease; LIHC cis rs2302777 0.507 rs1007655 chr17:38111419 G/A cg17467752 chr17:38218738 THRA 0.4 5.81 0.3 1.42e-8 Multiple myeloma (hyperdiploidy); LIHC cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.11 -0.44 7.26e-18 Bipolar disorder; LIHC cis rs2274273 0.870 rs17741542 chr14:55805861 A/G cg01864836 chr14:55583639 NA 0.38 6.75 0.34 6.47e-11 Protein biomarker; LIHC cis rs372883 0.600 rs2832295 chr21:30739843 C/T cg24692254 chr21:30365293 RNF160 0.5 6.26 0.32 1.18e-9 Pancreatic cancer; LIHC cis rs8078723 1.000 rs7214085 chr17:38169095 T/C cg17467752 chr17:38218738 THRA 0.75 13.71 0.6 2.07e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs898097 0.783 rs11650335 chr17:80835111 A/G cg15664640 chr17:80829946 TBCD -0.77 -12.66 -0.57 2.08e-30 Breast cancer; LIHC cis rs9309473 0.687 rs7576824 chr2:73611281 C/T cg20560298 chr2:73613845 ALMS1 0.44 7.01 0.35 1.25e-11 Metabolite levels; LIHC cis rs11148252 0.740 rs9596648 chr13:52934569 A/T cg00495681 chr13:53174319 NA -0.37 -5.91 -0.3 8.21e-9 Lewy body disease; LIHC cis rs9818758 0.607 rs9837625 chr3:49215966 C/T cg07636037 chr3:49044803 WDR6 -0.82 -7.97 -0.4 2.43e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9549367 0.789 rs2316442 chr13:113877487 C/T cg00898013 chr13:113819073 PROZ -0.41 -6.93 -0.35 2.16e-11 Platelet distribution width; LIHC cis rs700651 0.789 rs6434949 chr2:198855510 T/A cg00792783 chr2:198669748 PLCL1 0.45 6.56 0.33 2.04e-10 Intracranial aneurysm; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.43 -0.41 1e-15 Lymphocyte counts; LIHC cis rs6499255 0.951 rs12595878 chr16:69628217 C/T cg15192750 chr16:69999425 NA 0.45 6.86 0.35 3.22e-11 IgE levels; LIHC cis rs10744422 0.920 rs10773657 chr12:123327900 C/A cg25930673 chr12:123319894 HIP1R -0.87 -11.21 -0.52 4.95e-25 Schizophrenia; LIHC cis rs116095464 0.558 rs56298907 chr5:283280 C/A cg22496380 chr5:211416 CCDC127 -1.1 -10.33 -0.49 5.84e-22 Breast cancer; LIHC cis rs6977660 0.660 rs61670426 chr7:19790460 A/G cg07541023 chr7:19748670 TWISTNB 0.49 7.28 0.37 2.36e-12 Thyroid stimulating hormone; LIHC cis rs7116495 1.000 rs4943821 chr11:71813747 C/T cg26138937 chr11:71823887 C11orf51 0.7 7.11 0.36 6.68e-12 Severe influenza A (H1N1) infection; LIHC cis rs4974559 0.501 rs730830 chr4:1240091 T/C cg02980000 chr4:1222292 CTBP1 -0.86 -6.54 -0.33 2.22e-10 Systolic blood pressure; LIHC cis rs9911578 0.692 rs412000 chr17:56709058 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.53 7.36 0.37 1.35e-12 Intelligence (multi-trait analysis); LIHC cis rs7666738 0.830 rs7663924 chr4:99037679 A/G cg05340658 chr4:99064831 C4orf37 -0.7 -12.85 -0.57 4.03e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs17253792 0.822 rs78824140 chr14:56042715 G/T cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs847649 1.000 rs11514917 chr7:102609221 A/C cg18108683 chr7:102477205 FBXL13 -0.46 -6.88 -0.35 2.88e-11 Morning vs. evening chronotype; LIHC cis rs473651 0.904 rs551859 chr2:239371836 T/C cg18131467 chr2:239335373 ASB1 1.01 18.11 0.7 6.87e-52 Multiple system atrophy; LIHC cis rs17854409 1.000 rs66634465 chr20:61482306 C/T cg07645718 chr20:61493192 TCFL5 0.76 6.37 0.33 6.14e-10 Obesity-related traits; LIHC cis rs7193541 0.825 rs4411525 chr16:74595502 A/C cg01733217 chr16:74700730 RFWD3 0.54 9.96 0.47 1.12e-20 Multiple myeloma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18620298 chr10:76995799 COMTD1 -0.44 -6.13 -0.31 2.43e-9 Pancreatic cancer; LIHC cis rs425535 0.619 rs2367443 chr4:74818406 T/C cg02530824 chr4:74847766 PF4 -0.39 -6.31 -0.32 8.61e-10 Blood protein levels; LIHC cis rs10751667 1.000 rs10902233 chr11:925510 A/G cg06064525 chr11:970664 AP2A2 -0.49 -12.04 -0.55 4.67e-28 Alzheimer's disease (late onset); LIHC cis rs7572733 0.555 rs13395030 chr2:198750806 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.5e-11 Dermatomyositis; LIHC cis rs9902453 0.834 rs9901694 chr17:28271645 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 13.96 0.6 2.31e-35 Coffee consumption (cups per day); LIHC cis rs2979489 0.891 rs2915590 chr8:30393334 A/G cg26383811 chr8:30366931 RBPMS -0.67 -11.7 -0.53 8.28e-27 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs1878931 0.501 rs28735976 chr16:3418419 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.71 10.56 0.5 9.12e-23 Body mass index (adult); LIHC cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg05025164 chr4:1340916 KIAA1530 -0.39 -5.84 -0.3 1.24e-8 Obesity-related traits; LIHC cis rs9916302 0.904 rs7223331 chr17:37482930 A/G cg00129232 chr17:37814104 STARD3 0.39 6.16 0.32 2.01e-9 Glomerular filtration rate (creatinine); LIHC cis rs10193935 0.901 rs72798529 chr2:42537471 C/T cg27598129 chr2:42591480 NA -0.72 -10.76 -0.5 1.82e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs17001868 0.568 rs74424549 chr22:40736938 A/C cg07138101 chr22:40742427 ADSL 0.55 6.42 0.33 4.62e-10 Mammographic density (dense area); LIHC cis rs4721295 0.502 rs2058430 chr7:2206110 A/G cg04267008 chr7:1944627 MAD1L1 -0.54 -8.28 -0.41 2.8e-15 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs10504073 0.584 rs62507210 chr8:49946601 C/T cg00325661 chr8:49890786 NA 0.34 7.75 0.39 1.03e-13 Blood metabolite ratios; LIHC cis rs10504229 0.593 rs2317990 chr8:58024168 G/T cg20607798 chr8:58055168 NA 0.49 6.94 0.35 2.02e-11 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs8068427 chr17:37511517 G/A cg00129232 chr17:37814104 STARD3 0.38 6.11 0.31 2.67e-9 Glomerular filtration rate (creatinine); LIHC cis rs477895 0.713 rs35095324 chr11:63948412 G/A cg05555928 chr11:63887634 MACROD1 0.51 6.58 0.34 1.81e-10 Mean platelet volume; LIHC cis rs9467711 0.559 rs9393727 chr6:26500011 C/G cg12826209 chr6:26865740 GUSBL1 0.57 5.84 0.3 1.2e-8 Autism spectrum disorder or schizophrenia; LIHC trans rs208520 0.690 rs207082 chr6:66773796 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -9.04 -0.44 1.16e-17 Exhaled nitric oxide output; LIHC cis rs937213 0.573 rs2412464 chr15:40303842 G/A cg20255370 chr15:40268687 EIF2AK4 -0.37 -6.33 -0.32 7.51e-10 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs4243830 0.850 rs12030607 chr1:6601007 T/A cg22792644 chr1:6614718 TAS1R1;NOL9 1.0 12.74 0.57 1.07e-30 Body mass index; LIHC cis rs9300255 0.596 rs10732573 chr12:123743883 G/C cg00376283 chr12:123451042 ABCB9 0.65 9.87 0.47 2.22e-20 Neutrophil percentage of white cells; LIHC cis rs4423214 0.840 rs1792235 chr11:71181473 C/T cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC cis rs4919694 1.000 rs4917988 chr10:104752830 T/G cg04362960 chr10:104952993 NT5C2 1.06 8.05 0.4 1.39e-14 Arsenic metabolism; LIHC cis rs10791323 0.569 rs546381 chr11:133760651 T/G cg06766960 chr11:133703094 NA -0.41 -6.23 -0.32 1.4e-9 Childhood ear infection; LIHC cis rs17376456 0.569 rs7702348 chr5:93065683 A/G cg25358565 chr5:93447407 FAM172A -0.64 -6.66 -0.34 1.09e-10 Diabetic retinopathy; LIHC cis rs936229 1.000 rs936229 chr15:75132319 A/G cg14664628 chr15:75095509 CSK -0.86 -14.36 -0.61 6.34e-37 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs6502050 0.799 rs4482345 chr17:80152919 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.91 -0.3 8.14e-9 Life satisfaction; LIHC cis rs8062405 0.690 rs6498089 chr16:28629300 C/T cg07451762 chr16:28383216 NA -0.38 -6.42 -0.33 4.64e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1866706 0.896 rs7105759 chr11:12868817 T/A cg25843174 chr11:12811716 TEAD1 -0.32 -6.87 -0.35 2.96e-11 Intelligence (multi-trait analysis); LIHC cis rs370915 1.000 rs9685837 chr4:187818466 C/T cg12892747 chr4:187813459 NA -0.38 -6.07 -0.31 3.34e-9 Gout; LIHC cis rs8017423 0.967 rs12889636 chr14:90689953 A/C cg04374321 chr14:90722782 PSMC1 -0.74 -13.99 -0.6 1.75e-35 Mortality in heart failure; LIHC trans rs6598955 0.671 rs11247884 chr1:26577338 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC trans rs12310956 0.532 rs7967627 chr12:33974669 G/T cg26384229 chr12:38710491 ALG10B 0.49 6.71 0.34 8.25e-11 Morning vs. evening chronotype; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26628795 chr2:111435723 BUB1 0.41 6.39 0.33 5.35e-10 Lung function (FEV1/FVC); LIHC cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg17971929 chr21:40555470 PSMG1 0.81 9.38 0.45 9.51e-19 Cognitive function; LIHC cis rs4713118 0.513 rs183244 chr6:28031838 C/A cg23485639 chr6:28045615 ZNF165 0.38 5.77 0.3 1.75e-8 Parkinson's disease; LIHC trans rs2832077 0.527 rs1048546 chr21:30244877 G/T cg14791747 chr16:20752902 THUMPD1 0.63 9.83 0.47 3.07e-20 Cognitive test performance; LIHC cis rs9372498 0.505 rs1413630 chr6:118656434 A/G cg01339444 chr6:118972232 C6orf204 0.73 6.24 0.32 1.28e-9 Diastolic blood pressure; LIHC cis rs11122272 0.701 rs7414807 chr1:231476874 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.4 -0.49 3.45e-22 Hemoglobin concentration; LIHC cis rs6089829 0.962 rs4809455 chr20:61660781 G/C cg08564027 chr20:61660810 NA 0.4 7.67 0.38 1.84e-13 Prostate cancer (SNP x SNP interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23260255 chr3:187871479 LPP 0.47 6.76 0.34 5.84e-11 Pancreatic cancer; LIHC trans rs9641123 0.608 rs6943527 chr7:93205706 T/C cg09745688 chr16:2908918 PRSS22 -0.37 -6.35 -0.32 6.73e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs243505 0.559 rs2072408 chr7:148508197 A/G cg09806900 chr7:148480153 CUL1 0.39 5.78 0.3 1.68e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg13393036 chr8:95962371 TP53INP1 -0.37 -8.55 -0.42 4.1e-16 Type 2 diabetes; LIHC cis rs4407350 0.967 rs4501045 chr22:44922321 G/A cg11695653 chr22:44894386 LDOC1L -0.37 -6.08 -0.31 3.15e-9 Intelligence (multi-trait analysis); LIHC cis rs6831256 1.000 rs6831256 chr4:3473139 A/G cg22890737 chr4:3514540 LRPAP1 0.43 7.07 0.36 8.57e-12 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs892961 0.777 rs747483 chr17:75412091 C/T cg01320579 chr17:75405842 SEPT9 0.52 7.49 0.38 5.86e-13 Airflow obstruction; LIHC cis rs694739 0.541 rs61886926 chr11:64133552 C/T cg02228329 chr11:64053129 BAD;GPR137 0.6 8.21 0.41 4.45e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7727544 0.735 rs272881 chr5:131669264 G/A cg07395648 chr5:131743802 NA -0.3 -6.23 -0.32 1.34e-9 Blood metabolite levels; LIHC cis rs7847628 0.587 rs10760117 chr9:123586737 T/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.96 19.17 0.72 3.74e-56 Birth weight; LIHC cis rs72634258 0.520 rs12078018 chr1:7857309 G/A cg26816564 chr1:7831052 VAMP3 0.64 6.24 0.32 1.3e-9 Inflammatory bowel disease; LIHC trans rs875971 1.000 rs2420820 chr7:66091907 T/C cg10756647 chr7:56101905 PSPH -0.49 -7.23 -0.36 3.09e-12 Aortic root size; LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg21756720 chr8:11724777 CTSB -0.57 -7.04 -0.36 1.08e-11 Monocyte count; LIHC cis rs2760061 0.819 rs1745416 chr1:228204497 G/A cg01200585 chr1:228362443 C1orf69 0.41 6.17 0.32 1.96e-9 Diastolic blood pressure; LIHC cis rs8062405 0.755 rs55792032 chr16:28599411 A/G cg07451762 chr16:28383216 NA 0.4 7.15 0.36 5.4e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs921968 0.528 rs35695178 chr2:219589164 C/T cg02985541 chr2:219472218 PLCD4 -0.38 -6.66 -0.34 1.07e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1371867 0.846 rs1788199 chr8:101292854 A/G cg06636551 chr8:101224915 SPAG1 -0.5 -9.05 -0.44 1.13e-17 Atrioventricular conduction; LIHC cis rs1018836 0.923 rs6986088 chr8:91538474 A/C cg16814680 chr8:91681699 NA -0.63 -10.23 -0.48 1.32e-21 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.58 0.56 4.27e-30 Colorectal cancer; LIHC cis rs2204008 0.782 rs11514339 chr12:38236670 G/A cg13010199 chr12:38710504 ALG10B 0.5 5.85 0.3 1.14e-8 Bladder cancer; LIHC cis rs60871478 0.730 rs73042471 chr7:927762 G/A cg05535760 chr7:792225 HEATR2 -0.78 -5.83 -0.3 1.32e-8 Cerebrospinal P-tau181p levels; LIHC cis rs3796352 1.000 rs35174175 chr3:53041509 T/C cg07884673 chr3:53033167 SFMBT1 0.92 6.74 0.34 6.85e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7223966 1.000 rs11657120 chr17:61857218 G/A cg05941027 chr17:61774174 LIMD2 0.35 7.39 0.37 1.13e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2479724 0.935 rs1887718 chr6:41857691 C/T cg17623882 chr6:41773611 USP49 -0.54 -8.53 -0.42 4.86e-16 Menarche (age at onset); LIHC cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg12310025 chr6:25882481 NA -0.64 -9.01 -0.44 1.54e-17 Blood metabolite levels; LIHC cis rs8180040 1.000 rs295428 chr3:47359262 G/T cg16586182 chr3:47516702 SCAP -0.54 -9.86 -0.47 2.43e-20 Colorectal cancer; LIHC cis rs3823572 0.564 rs6949760 chr7:133676101 C/A cg03336402 chr7:133662267 EXOC4 -0.48 -5.77 -0.3 1.76e-8 Intelligence (multi-trait analysis); LIHC cis rs55665837 0.540 rs4144487 chr11:14750451 C/G cg25251204 chr11:14927456 NA 0.4 5.74 0.3 2.11e-8 Vitamin D levels; LIHC cis rs61440199 0.818 rs76854494 chr3:20179496 G/C cg00235661 chr3:20228976 SGOL1 -0.42 -5.79 -0.3 1.58e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs9640161 0.830 rs35635199 chr7:150063342 C/T cg17279839 chr7:150038598 RARRES2 0.39 7.59 0.38 3.06e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs634534 0.561 rs14157 chr11:65769780 T/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.25 0.45 2.49e-18 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg12373951 chr3:133503437 NA -0.75 -14.55 -0.62 1.13e-37 Iron status biomarkers; LIHC cis rs11958404 0.860 rs7730844 chr5:157461208 C/T cg05962755 chr5:157440814 NA 1.01 11.11 0.52 1.05e-24 IgG glycosylation; LIHC cis rs72627509 1.000 rs57265257 chr4:57839280 A/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.6 -8.85 -0.43 4.76e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4268898 0.552 rs35331966 chr2:24367828 C/T cg06627628 chr2:24431161 ITSN2 0.46 6.69 0.34 8.94e-11 Asthma; LIHC cis rs1008375 0.932 rs6844593 chr4:17659039 T/C cg16339924 chr4:17578868 LAP3 0.53 7.01 0.35 1.27e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7412746 0.658 rs11589458 chr1:150792616 A/G cg18016565 chr1:150552671 MCL1 0.53 10.02 0.48 6.66e-21 Melanoma; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00428944 chr8:101963525 YWHAZ 0.35 6.48 0.33 3.21e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17685 0.753 rs11982200 chr7:75714883 T/C cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs763121 0.853 rs4821810 chr22:39072098 C/G cg06544989 chr22:39130855 UNC84B 0.36 5.89 0.3 9.2e-9 Menopause (age at onset); LIHC cis rs2268241 0.938 rs7283827 chr21:34769904 A/G cg14850771 chr21:34775459 IFNGR2 0.86 13.15 0.58 2.98e-32 Obesity-related traits; LIHC cis rs798554 0.660 rs2283783 chr7:2855326 G/A cg19717773 chr7:2847554 GNA12 -0.43 -7.62 -0.38 2.58e-13 Height; LIHC cis rs7208859 0.623 rs58908911 chr17:29244558 C/T cg14067834 chr17:29058358 SUZ12P 0.6 5.9 0.3 8.71e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9649213 0.593 rs12704983 chr7:97927045 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.82e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg22800045 chr5:56110881 MAP3K1 -0.57 -6.79 -0.34 4.89e-11 Initial pursuit acceleration; LIHC trans rs4942242 0.663 rs9525812 chr13:44200099 T/C cg19169023 chr15:41853346 TYRO3 -0.52 -7.15 -0.36 5.3e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs66887589 0.967 rs13104219 chr4:120438174 G/T cg09307838 chr4:120376055 NA 0.49 7.45 0.37 7.66e-13 Diastolic blood pressure; LIHC cis rs7100689 0.784 rs7089058 chr10:82071263 T/C cg01528321 chr10:82214614 TSPAN14 0.87 11.96 0.54 8.55e-28 Post bronchodilator FEV1; LIHC cis rs1775715 0.678 rs7096139 chr10:32217404 A/C cg14930904 chr10:32216787 ARHGAP12 0.37 6.7 0.34 8.5e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs651907 0.557 rs1031710 chr3:101463895 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.4 0.52 9.54e-26 Colorectal cancer; LIHC cis rs758324 0.947 rs1875177 chr5:131202625 T/C cg06307176 chr5:131281290 NA 0.41 5.88 0.3 9.87e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs864643 1.000 rs816494 chr3:39556845 T/C cg05136238 chr3:39556330 MOBP 0.32 5.78 0.3 1.65e-8 Attention deficit hyperactivity disorder; LIHC cis rs10463316 0.894 rs6579862 chr5:150761717 T/G cg03212797 chr5:150827313 SLC36A1 -0.42 -6.35 -0.32 7.04e-10 Metabolite levels (Pyroglutamine); LIHC cis rs8180040 0.653 rs6808742 chr3:47051512 G/A cg27129171 chr3:47204927 SETD2 0.66 11.64 0.53 1.38e-26 Colorectal cancer; LIHC cis rs6088580 0.634 rs6059779 chr20:32950325 C/T cg08999081 chr20:33150536 PIGU -0.66 -13.2 -0.58 1.87e-32 Glomerular filtration rate (creatinine); LIHC cis rs72781680 1.000 rs55982282 chr2:24188128 G/A cg08917208 chr2:24149416 ATAD2B 0.9 8.01 0.4 1.83e-14 Lymphocyte counts; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16249105 chr10:120938029 PRDX3 -0.39 -6.03 -0.31 4.15e-9 Longevity; LIHC cis rs76419734 0.558 rs10019217 chr4:106588509 C/T cg24545054 chr4:106630052 GSTCD;INTS12 0.68 8.27 0.41 2.98e-15 Post bronchodilator FEV1; LIHC cis rs2153535 0.580 rs5001324 chr6:8451604 A/T cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC cis rs2463822 0.920 rs28678254 chr11:62151875 G/C cg06239285 chr11:62104954 ASRGL1 -0.96 -7.04 -0.36 1.06e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs10256972 0.804 rs10275585 chr7:1017339 T/C cg23978390 chr7:1156363 C7orf50 0.47 6.63 0.34 1.3e-10 Longevity;Endometriosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05095774 chr18:52495848 RAB27B 0.45 6.35 0.32 6.99e-10 Lung function (FEV1/FVC); LIHC cis rs637571 0.565 rs570387 chr11:65637076 T/C cg04055107 chr11:65626734 MUS81;CFL1 -0.51 -7.54 -0.38 4.25e-13 Eosinophil percentage of white cells; LIHC cis rs6456156 0.586 rs10946209 chr6:167480991 G/A cg12798992 chr6:167411361 FGFR1OP 0.41 6.36 0.33 6.61e-10 Primary biliary cholangitis; LIHC cis rs1008375 0.966 rs11733730 chr4:17625209 G/C cg16339924 chr4:17578868 LAP3 0.44 6.2 0.32 1.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4728302 0.869 rs7792492 chr7:133595316 C/T cg10665199 chr7:133106180 EXOC4 0.33 5.88 0.3 9.78e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs559928 0.597 rs11600667 chr11:63976183 C/T cg02228329 chr11:64053129 BAD;GPR137 0.62 5.79 0.3 1.58e-8 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC trans rs916888 0.610 rs199530 chr17:44836653 C/T cg22968622 chr17:43663579 NA -0.47 -6.84 -0.35 3.58e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1144333 0.655 rs76735776 chr1:76455211 A/G cg10523679 chr1:76189770 ACADM 0.45 5.99 0.31 5.31e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs9768139 0.683 rs7779781 chr7:158115071 T/C cg25566285 chr7:158114605 PTPRN2 0.23 6.15 0.32 2.11e-9 Calcium levels; LIHC cis rs11112613 0.762 rs17037312 chr12:105950085 C/T cg03607813 chr12:105948248 NA 0.67 13.37 0.59 4.49e-33 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg06212747 chr3:49208901 KLHDC8B 0.63 8.63 0.42 2.28e-16 Menarche (age at onset); LIHC cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg07424592 chr7:64974309 NA -0.8 -9.08 -0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs74181299 0.819 rs2723087 chr2:65298282 T/A cg05010058 chr2:65284262 CEP68 0.38 6.39 0.33 5.38e-10 Pulse pressure; LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg18538332 chr22:24372958 LOC391322 0.62 9.23 0.45 2.91e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.47 -0.49 1.91e-22 Platelet count; LIHC cis rs769267 0.629 rs7245672 chr19:19699963 T/C cg03709012 chr19:19516395 GATAD2A -0.71 -9.88 -0.47 2.09e-20 Tonsillectomy; LIHC cis rs311392 0.525 rs366276 chr8:55100181 T/C cg20636351 chr8:55087400 NA -0.35 -7.27 -0.37 2.47e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs7903847 0.673 rs3818908 chr10:99132701 A/G cg20016023 chr10:99160130 RRP12 -0.41 -6.48 -0.33 3.22e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11683229 0.778 rs72811598 chr2:63326416 T/G cg17519650 chr2:63277830 OTX1 -0.51 -5.79 -0.3 1.6e-8 Protein quantitative trait loci; LIHC cis rs4819052 0.851 rs13052344 chr21:46676101 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.58 0.53 2.2e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3784262 1.000 rs7495968 chr15:58244103 C/G cg12031962 chr15:58353849 ALDH1A2 0.33 6.42 0.33 4.55e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6952808 0.531 rs3778998 chr7:2180753 C/A cg02951883 chr7:2050386 MAD1L1 -0.6 -9.62 -0.46 1.5700000000000001e-19 Bipolar disorder and schizophrenia; LIHC cis rs1799949 0.859 rs11657004 chr17:41442751 A/G cg25072359 chr17:41440525 NA 0.38 6.07 0.31 3.46e-9 Menopause (age at onset); LIHC cis rs1030877 0.924 rs2250658 chr2:105889683 C/T cg02079111 chr2:105885981 TGFBRAP1 0.68 11.96 0.54 8.99e-28 Obesity-related traits; LIHC cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg23758822 chr17:41437982 NA 0.94 17.78 0.69 1.48e-50 Menopause (age at onset); LIHC cis rs10838687 0.673 rs77532017 chr11:47284317 C/T cg26139080 chr11:47293733 MADD -0.42 -5.88 -0.3 9.67e-9 Proinsulin levels; LIHC cis rs1185460 0.546 rs7114961 chr11:118914388 G/C cg23280166 chr11:118938394 VPS11 -0.43 -5.99 -0.31 5.35e-9 Coronary artery disease; LIHC cis rs7223966 1.000 rs9909992 chr17:61731931 G/A cg05941027 chr17:61774174 LIMD2 0.32 6.53 0.33 2.43e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7582180 0.629 rs4851294 chr2:100941109 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.68 0.43 1.6e-16 Intelligence (multi-trait analysis); LIHC cis rs483180 0.512 rs612430 chr1:120216025 A/G cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Macular telangiectasia type 2; LIHC cis rs1113500 0.787 rs10881502 chr1:108641819 C/T cg06207961 chr1:108661230 NA -0.32 -6.1 -0.31 2.89e-9 Growth-regulated protein alpha levels; LIHC cis rs10078 0.571 rs2561664 chr5:459793 T/C cg26072250 chr5:443457 EXOC3;C5orf55 0.76 10.15 0.48 2.45e-21 Fat distribution (HIV); LIHC cis rs2180341 0.782 rs6912552 chr6:127722946 C/G cg27446573 chr6:127587934 RNF146 -0.83 -13.36 -0.59 4.91e-33 Breast cancer; LIHC cis rs8017423 0.935 rs11628906 chr14:90738002 C/T cg14092571 chr14:90743983 NA 0.46 7.25 0.37 2.76e-12 Mortality in heart failure; LIHC cis rs66573146 0.656 rs111560662 chr4:6952766 C/T cg00086871 chr4:6988644 TBC1D14 0.89 6.27 0.32 1.07e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs11165623 0.792 rs1125358 chr1:96971800 T/C cg10631902 chr5:14652156 NA -0.29 -6.69 -0.34 9.41e-11 Hip circumference;Waist circumference; LIHC cis rs651907 0.557 rs2318090 chr3:101474933 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 10.88 0.51 7.4e-24 Colorectal cancer; LIHC cis rs1552244 0.808 rs7615088 chr3:10035896 A/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13401831 chr22:18593307 TUBA8 0.44 6.49 0.33 3.09e-10 Pancreatic cancer; LIHC cis rs9733 0.596 rs12063547 chr1:150674053 G/T cg17724175 chr1:150552817 MCL1 -0.47 -9.59 -0.46 1.94e-19 Tonsillectomy; LIHC cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.0 -0.35 1.4e-11 Bipolar disorder; LIHC cis rs9381040 0.655 rs6903444 chr6:41014220 C/T cg04346459 chr6:41068666 NFYA;LOC221442 0.42 6.77 0.34 5.5e-11 Alzheimer's disease (late onset); LIHC cis rs1552244 0.554 rs6762397 chr3:10007840 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.99 -0.35 1.48e-11 Alzheimer's disease; LIHC cis rs6459788 0.657 rs887627 chr7:157237391 G/A cg06271696 chr7:157225062 NA -0.47 -7.32 -0.37 1.84e-12 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs7131987 0.650 rs6487808 chr12:29463359 C/T cg12903224 chr12:29470962 FAR2 0.39 6.52 0.33 2.58e-10 QT interval; LIHC cis rs7224685 0.569 rs7212168 chr17:4024640 G/A cg09597638 chr17:3907349 NA 0.55 6.74 0.34 6.86e-11 Type 2 diabetes; LIHC cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg21724239 chr8:58056113 NA 0.49 6.53 0.33 2.43e-10 Developmental language disorder (linguistic errors); LIHC cis rs17253792 0.545 rs12894368 chr14:56025178 C/A cg01858014 chr14:56050164 KTN1 -0.67 -6.11 -0.31 2.74e-9 Putamen volume; LIHC cis rs7927592 0.956 rs11228251 chr11:68244558 G/T cg20283391 chr11:68216788 NA -0.52 -7.97 -0.4 2.38e-14 Total body bone mineral density; LIHC cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg07092213 chr7:1199455 ZFAND2A -0.45 -6.54 -0.33 2.26e-10 Longevity;Endometriosis; LIHC cis rs55702914 0.809 rs2376407 chr2:198183465 A/G cg10820045 chr2:198174542 NA -0.4 -5.93 -0.31 7.39e-9 Major depression and alcohol dependence; LIHC cis rs2235642 0.717 rs9937922 chr16:1658154 C/G cg03034668 chr16:1723424 CRAMP1L -0.39 -6.88 -0.35 2.88e-11 Coronary artery disease; LIHC cis rs589448 0.538 rs683790 chr12:69751434 T/G cg20891283 chr12:69753455 YEATS4 0.84 16.18 0.66 3.89e-44 Cerebrospinal fluid biomarker levels; LIHC cis rs151997 1.000 rs251043 chr5:50215997 A/G cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg26818010 chr10:134567672 INPP5A -0.69 -9.1 -0.44 7.83e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2075371 0.933 rs2544181 chr7:133944934 C/T cg11752832 chr7:134001865 SLC35B4 0.51 7.74 0.39 1.16e-13 Mean platelet volume; LIHC cis rs116248771 0.549 rs9849301 chr3:158444860 C/T cg16708174 chr3:158430962 RARRES1 0.7 9.25 0.45 2.45e-18 diarrhoeal disease at age 2; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18125326 chr3:88112162 NA 0.28 6.17 0.32 1.92e-9 Cognitive function; LIHC cis rs2153535 0.580 rs9505457 chr6:8479142 C/T cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg15691649 chr6:25882328 NA -0.38 -5.97 -0.31 5.87e-9 Height; LIHC cis rs782590 0.967 rs782586 chr2:55836165 A/C cg18811423 chr2:55921094 PNPT1 1.0 16.0 0.65 2.04e-43 Metabolic syndrome; LIHC cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg18357526 chr6:26021779 HIST1H4A -0.51 -7.27 -0.37 2.53e-12 Blood metabolite levels; LIHC cis rs116095464 0.558 rs62346526 chr5:220614 T/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs477692 1.000 rs7475154 chr10:131440584 C/T cg05714579 chr10:131428358 MGMT -0.45 -7.3 -0.37 2.09e-12 Response to temozolomide; LIHC cis rs10779751 1.000 rs11121704 chr1:11293959 A/G cg08854313 chr1:11322531 MTOR -0.73 -9.99 -0.48 8.45e-21 Body mass index; LIHC cis rs2115536 0.967 rs934137 chr15:80211768 T/C cg00225070 chr15:80189496 MTHFS 0.53 8.65 0.42 2.04e-16 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.58 -8.27 -0.41 2.98e-15 Lymphocyte counts; LIHC cis rs904251 0.861 rs914349 chr6:37484715 A/C cg25019722 chr6:37503610 NA -0.35 -6.02 -0.31 4.52e-9 Cognitive performance; LIHC cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC trans rs61931739 0.500 rs6488221 chr12:34525671 A/G cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs1775715 0.870 rs10827001 chr10:32229734 C/T cg14930904 chr10:32216787 ARHGAP12 0.37 6.4 0.33 5.1e-10 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15724272 chr4:89513644 HERC3 -0.44 -6.2 -0.32 1.67e-9 Pancreatic cancer; LIHC cis rs1506636 0.962 rs1506640 chr7:123349627 T/G cg03229431 chr7:123269106 ASB15 -0.59 -11.98 -0.54 7.63e-28 Plateletcrit;Platelet count; LIHC cis rs8017423 1.000 rs8011810 chr14:90685669 A/G cg14092571 chr14:90743983 NA -0.36 -5.76 -0.3 1.89e-8 Mortality in heart failure; LIHC cis rs3762637 0.882 rs9856011 chr3:122093570 G/A cg24169773 chr3:122142474 KPNA1 -0.49 -9.58 -0.46 2.06e-19 LDL cholesterol levels; LIHC cis rs4689592 0.523 rs6446565 chr4:7074027 A/G cg26116260 chr4:7069785 GRPEL1 1.0 18.68 0.71 3.43e-54 Monocyte percentage of white cells; LIHC cis rs7833790 0.724 rs12676336 chr8:82771008 C/T cg02079420 chr8:82753780 SNX16 -0.36 -6.59 -0.34 1.63e-10 Diastolic blood pressure; LIHC trans rs4332037 0.754 rs62436669 chr7:1926636 G/A cg11693508 chr17:37793320 STARD3 0.71 7.24 0.36 3.06e-12 Bipolar disorder; LIHC cis rs9611565 0.649 rs5758434 chr22:42116163 G/A cg03806693 chr22:41940476 POLR3H 0.8 9.01 0.44 1.46e-17 Vitiligo; LIHC cis rs1865721 0.804 rs4510115 chr18:73209635 G/A cg26385618 chr18:73139727 C18orf62 -0.29 -7.4 -0.37 1.08e-12 Intelligence; LIHC cis rs600806 0.850 rs11102981 chr1:109967323 G/C cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.54 -0.38 4.39e-13 Intelligence (multi-trait analysis); LIHC cis rs17685 0.725 rs6467993 chr7:75719350 G/A cg16684958 chr7:75615977 POR 0.51 8.59 0.42 3.18e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs921968 0.565 rs6436081 chr2:219637884 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.39 -0.33 5.39e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2120019 0.938 rs3850093 chr15:75318482 A/G cg06012730 chr15:75315579 PPCDC 0.37 6.86 0.35 3.32e-11 Blood trace element (Zn levels); LIHC cis rs56011263 0.687 rs4690293 chr4:706101 A/G cg14024328 chr4:719362 PCGF3 -0.47 -7.11 -0.36 6.72e-12 White blood cell count; LIHC cis rs7772486 0.754 rs9386133 chr6:146141213 A/G cg13319975 chr6:146136371 FBXO30 -0.37 -6.23 -0.32 1.37e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg12042659 chr19:58951599 ZNF132 0.39 6.46 0.33 3.57e-10 Uric acid clearance; LIHC cis rs7267979 1.000 rs2258201 chr20:25272490 G/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs597539 0.690 rs578791 chr11:68625809 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.71 9.91 0.47 1.58e-20 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9926296 0.715 rs467035 chr16:89740285 C/G cg03605463 chr16:89740564 NA -0.51 -5.73 -0.3 2.17e-8 Vitiligo; LIHC cis rs4908768 0.539 rs6663123 chr1:8642931 T/C cg20416874 chr1:8611966 RERE -0.64 -12.92 -0.57 2.27e-31 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3736594 0.959 rs10201247 chr2:27974971 A/G cg27432699 chr2:27873401 GPN1 -0.43 -6.7 -0.34 8.46e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs11955398 0.716 rs1379117 chr5:59942309 T/C cg02684056 chr5:59996105 DEPDC1B 0.4 5.92 0.3 7.95e-9 Intelligence (multi-trait analysis); LIHC cis rs4423214 0.840 rs1792231 chr11:71182681 G/A cg05163923 chr11:71159392 DHCR7 -0.61 -8.03 -0.4 1.61e-14 Vitamin D levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg23174392 chr13:114009751 GRTP1 0.37 6.41 0.33 4.8e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg12379764 chr21:47803548 PCNT -0.54 -7.8 -0.39 7.58e-14 Testicular germ cell tumor; LIHC cis rs17608059 0.545 rs736261 chr17:13936404 A/G cg27005118 chr17:13972210 COX10 -0.38 -7.24 -0.36 2.91e-12 Temperament; LIHC cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs2153535 0.580 rs1115079 chr6:8449615 G/C cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs1865760 0.892 rs6456705 chr6:25936056 G/A cg03264133 chr6:25882463 NA -0.41 -6.22 -0.32 1.48e-9 Height; LIHC cis rs17376456 0.877 rs9314092 chr5:93326362 A/G cg25358565 chr5:93447407 FAM172A 1.07 9.91 0.47 1.57e-20 Diabetic retinopathy; LIHC cis rs798554 0.797 rs798488 chr7:2802522 T/C cg04166393 chr7:2884313 GNA12 0.43 6.02 0.31 4.48e-9 Height; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg07685765 chr19:48964041 KCNJ14 -0.33 -6.38 -0.33 5.75e-10 Calcium levels; LIHC cis rs9790314 0.521 rs13084731 chr3:161086020 G/A cg03342759 chr3:160939853 NMD3 -0.43 -6.25 -0.32 1.23e-9 Morning vs. evening chronotype; LIHC cis rs8027181 1.000 rs2162269 chr15:73090262 C/T cg25632853 chr15:73088954 NA 0.37 6.17 0.32 1.93e-9 Triglyceride levels; LIHC cis rs11190604 0.943 rs7085261 chr10:102209811 G/A cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs8073060 0.559 rs72829925 chr17:34049778 C/A cg19694781 chr19:47549865 TMEM160 1.25 13.52 0.59 1.15e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs12701220 0.655 rs7799656 chr7:1140515 C/T cg18765753 chr7:1198926 ZFAND2A -0.43 -6.18 -0.32 1.81e-9 Bronchopulmonary dysplasia; LIHC cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg25894440 chr7:65020034 NA -0.52 -5.79 -0.3 1.6e-8 Diabetic kidney disease; LIHC cis rs11971779 0.680 rs6467848 chr7:139080205 T/A cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.41e-21 Diisocyanate-induced asthma; LIHC cis rs2204008 0.774 rs11520273 chr12:38354075 A/T cg26384229 chr12:38710491 ALG10B 0.57 7.88 0.39 4.37e-14 Bladder cancer; LIHC cis rs8017423 1.000 rs2184281 chr14:90685923 A/G cg04374321 chr14:90722782 PSMC1 -0.73 -13.59 -0.59 6.38e-34 Mortality in heart failure; LIHC cis rs7238033 0.663 rs12454680 chr18:43321417 T/C cg20610511 chr18:43302872 SLC14A1 0.35 5.82 0.3 1.37e-8 Bladder cancer; LIHC cis rs7818688 0.697 rs74633621 chr8:95981037 A/G cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs10751667 0.643 rs6597969 chr11:928843 C/T cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs12594515 1.000 rs8033148 chr15:45997929 G/A cg01629716 chr15:45996671 NA 0.51 9.21 0.45 3.44e-18 Waist circumference;Weight; LIHC cis rs748404 0.697 rs491804 chr15:43560825 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.45 6.85 0.35 3.49e-11 Lung cancer; LIHC cis rs7208859 0.615 rs216462 chr17:28895897 T/C cg14067834 chr17:29058358 SUZ12P -0.65 -6.17 -0.32 1.9e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6906287 0.625 rs9320649 chr6:118693665 A/G cg20689054 chr4:153457152 FBXW7 0.41 6.03 0.31 4.17e-9 Electrocardiographic conduction measures; LIHC cis rs7587476 0.862 rs13001462 chr2:215678346 G/A cg04530015 chr2:215796436 ABCA12 -0.4 -6.57 -0.33 1.86e-10 Neuroblastoma; LIHC cis rs11628318 0.614 rs12590775 chr14:103150623 A/G cg01864069 chr14:103024347 NA 0.36 5.96 0.31 6.38e-9 Platelet count; LIHC cis rs5769765 1.000 rs5769764 chr22:50270784 G/A cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs10791097 0.720 rs6590517 chr11:130733505 C/T cg22079354 chr11:130786696 SNX19 0.42 6.03 0.31 4.18e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6138458 1.000 rs6114981 chr20:24974401 C/T cg26195577 chr20:24973756 C20orf3 -1.2 -16.23 -0.66 2.61e-44 Blood protein levels; LIHC cis rs9910055 0.530 rs7222349 chr17:42304644 C/T cg09913183 chr17:42254507 C17orf65;ASB16 0.65 9.41 0.45 7.48e-19 Total body bone mineral density; LIHC cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.34 0.55 3.52e-29 Alzheimer's disease; LIHC cis rs6964587 0.967 rs2282969 chr7:91583772 T/C cg17063962 chr7:91808500 NA -1.02 -19.42 -0.72 3.74e-57 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04794120 chr7:48019205 HUS1 -0.48 -7.16 -0.36 4.99e-12 Pancreatic cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07551314 chr1:26190155 PAQR7 0.5 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg12463550 chr7:65579703 CRCP 0.68 7.05 0.36 9.9e-12 Diabetic kidney disease; LIHC cis rs6466055 0.720 rs6466064 chr7:105024217 T/C cg04380332 chr7:105027541 SRPK2 -0.37 -6.88 -0.35 2.83e-11 Schizophrenia; LIHC cis rs644799 1.000 rs544119 chr11:95538624 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2760061 0.583 rs3094911 chr1:228210179 A/G cg02753203 chr1:228287806 NA 0.67 11.66 0.53 1.11e-26 Diastolic blood pressure; LIHC cis rs6840360 0.550 rs6853955 chr4:152510806 G/A cg22705602 chr4:152727874 NA -0.32 -6.19 -0.32 1.73e-9 Intelligence (multi-trait analysis); LIHC cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg25364880 chr3:44379878 C3orf23 0.42 5.89 0.3 9.11e-9 Depressive symptoms; LIHC cis rs9322817 0.583 rs7741733 chr6:105182839 T/C cg02098413 chr6:105308735 HACE1 -0.43 -7.78 -0.39 8.37e-14 Thyroid stimulating hormone; LIHC trans rs916888 0.773 rs199535 chr17:44822662 A/G cg16836995 chr17:43662488 NA -0.76 -7.71 -0.38 1.41e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10823500 0.777 rs2184335 chr10:72006891 C/T cg04118878 chr10:71993077 PPA1 0.57 5.75 0.3 1.98e-8 Blood protein levels; LIHC cis rs12477438 0.520 rs13018891 chr2:99755099 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.23 0.61 1.96e-36 Chronic sinus infection; LIHC cis rs2834188 1.000 rs2252930 chr21:34704201 C/G cg04842828 chr21:34696676 IFNAR1 -0.49 -6.32 -0.32 7.97e-10 Narcolepsy; LIHC trans rs116095464 0.558 rs10462754 chr5:246669 T/C cg00938859 chr5:1591904 SDHAP3 0.57 7.09 0.36 7.91e-12 Breast cancer; LIHC cis rs2842992 0.872 rs2758315 chr6:160158640 T/C cg16489826 chr6:160211363 TCP1;MRPL18 0.55 9.69 0.46 9.09e-20 Age-related macular degeneration (geographic atrophy); LIHC cis rs7208859 0.524 rs73988172 chr17:29086332 A/C cg14067834 chr17:29058358 SUZ12P 0.72 7.34 0.37 1.56e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2404602 0.710 rs2469541 chr15:76562118 C/T cg22467129 chr15:76604101 ETFA 0.38 6.24 0.32 1.29e-9 Blood metabolite levels; LIHC cis rs425277 0.606 rs2459984 chr1:2086312 A/G cg24578937 chr1:2090814 PRKCZ 0.31 5.76 0.3 1.91e-8 Height; LIHC cis rs11690935 0.610 rs59844139 chr2:172731983 C/A cg13550731 chr2:172543902 DYNC1I2 0.57 10.04 0.48 5.69e-21 Schizophrenia; LIHC cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg03806693 chr22:41940476 POLR3H 0.99 10.63 0.5 5.22e-23 Vitiligo; LIHC cis rs7666738 0.515 rs13434650 chr4:98889886 A/G cg05340658 chr4:99064831 C4orf37 0.52 6.91 0.35 2.38e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs6570726 0.599 rs455001 chr6:145854450 A/T cg05347473 chr6:146136440 FBXO30 0.45 6.79 0.34 4.94e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg20237920 chr15:76225808 FBXO22OS;FBXO22 0.38 6.08 0.31 3.17e-9 Myopia (pathological); LIHC cis rs1670533 1.000 rs651017 chr4:1091062 A/G cg27284194 chr4:1044797 NA 0.54 7.99 0.4 2.1e-14 Recombination rate (females); LIHC trans rs2243480 0.615 rs34363376 chr7:65939536 T/C cg10756647 chr7:56101905 PSPH 1.0 11.4 0.52 9.84e-26 Diabetic kidney disease; LIHC cis rs6062302 0.522 rs2872810 chr20:62241931 C/T cg09650180 chr20:62225654 GMEB2 0.38 5.91 0.3 8.21e-9 Glioblastoma; LIHC cis rs1670533 1.000 rs13134921 chr4:1054177 A/G cg27284194 chr4:1044797 NA 0.6 8.97 0.44 1.94e-17 Recombination rate (females); LIHC trans rs11098499 0.865 rs4507344 chr4:120307485 C/A cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs60871478 0.947 rs7790823 chr7:788923 T/G cg05535760 chr7:792225 HEATR2 0.79 11.07 0.51 1.51e-24 Cerebrospinal P-tau181p levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06348038 chr1:207038460 IL20 0.5 6.8 0.35 4.6e-11 Lung function (FEV1/FVC); LIHC cis rs12950390 0.776 rs4793646 chr17:45853966 A/C cg03474202 chr17:45855739 NA -0.34 -5.97 -0.31 6.05e-9 IgG glycosylation; LIHC cis rs1552244 0.882 rs6443279 chr3:10053599 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.59 0.5 7.6e-23 Alzheimer's disease; LIHC trans rs4714291 0.832 rs6917417 chr6:40104628 T/C cg02267698 chr19:7991119 CTXN1 -0.4 -6.6 -0.34 1.56e-10 Strep throat; LIHC cis rs11229555 0.609 rs34133416 chr11:58184720 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9467711 0.606 rs67234939 chr6:26530419 A/G cg12826209 chr6:26865740 GUSBL1 0.59 5.94 0.31 6.99e-9 Autism spectrum disorder or schizophrenia; LIHC trans rs5756813 0.754 rs11705616 chr22:38180487 G/T cg19894588 chr14:64061835 NA -0.62 -8.58 -0.42 3.38e-16 Optic cup area;Vertical cup-disc ratio; LIHC cis rs9611519 0.929 rs13055800 chr22:41440424 G/A cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.13e-14 Neuroticism; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg02290350 chr8:58132656 NA 0.49 8.83 0.43 5.72e-17 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg20607798 chr8:58055168 NA 0.62 7.23 0.36 3.17e-12 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.788 rs9978857 chr21:46705155 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.62 8.98 0.44 1.89e-17 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg00684032 chr4:1343700 KIAA1530 0.52 7.57 0.38 3.55e-13 Obesity-related traits; LIHC cis rs7818688 0.697 rs11783878 chr8:95979261 C/T cg16049864 chr8:95962084 TP53INP1 -0.52 -5.95 -0.31 6.53e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs9534288 0.797 rs1326401 chr13:46571602 A/G cg15192986 chr13:46630673 CPB2 0.54 8.38 0.41 1.42e-15 Blood protein levels; LIHC cis rs4820539 0.966 rs2267001 chr22:23456696 T/C cg21100191 chr22:23484243 RTDR1 0.84 14.73 0.62 2.31e-38 Bone mineral density; LIHC cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg02290350 chr8:58132656 NA 0.42 8.88 0.43 3.83e-17 Developmental language disorder (linguistic errors); LIHC cis rs9648428 0.515 rs11974488 chr7:36202112 G/T cg14708893 chr7:36124863 NA -0.41 -6.18 -0.32 1.79e-9 Obesity-related traits; LIHC cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg18876405 chr7:65276391 NA 0.56 9.46 0.46 5.21e-19 Aortic root size; LIHC cis rs986417 0.818 rs8008804 chr14:61082357 A/T cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs17106184 0.786 rs1278518 chr1:50897841 T/C cg07174182 chr1:51127561 FAF1 -0.6 -6.69 -0.34 9.09e-11 Type 2 diabetes; LIHC cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -11.05 -0.51 1.74e-24 Platelet count; LIHC cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg07092213 chr7:1199455 ZFAND2A -0.42 -6.22 -0.32 1.43e-9 Longevity;Endometriosis; LIHC cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg12792011 chr19:58661915 ZNF329 0.96 8.01 0.4 1.76e-14 Cholesterol, total; LIHC cis rs3806843 0.735 rs3776129 chr5:140072292 G/A cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs2204008 0.715 rs11514342 chr12:38236710 T/A cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs10489202 0.954 rs3820399 chr1:168062053 C/T cg24449463 chr1:168025552 DCAF6 -0.5 -6.35 -0.32 6.76e-10 Schizophrenia; LIHC cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.44 6.11 0.31 2.71e-9 Schizophrenia; LIHC cis rs2845885 0.744 rs2701540 chr11:63869107 T/A cg24431193 chr11:63883947 FLRT1;MACROD1 -0.59 -7.67 -0.38 1.84e-13 Body mass index; LIHC cis rs3018712 0.532 rs2510396 chr11:68417652 G/C cg16797656 chr11:68205561 LRP5 -0.44 -5.79 -0.3 1.56e-8 Total body bone mineral density; LIHC cis rs9916302 0.706 rs6503504 chr17:37514412 A/G cg07936489 chr17:37558343 FBXL20 0.85 12.19 0.55 1.26e-28 Glomerular filtration rate (creatinine); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23394849 chr1:38006089 SNIP1 -0.48 -7.08 -0.36 8.27e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs12477438 0.798 rs4850891 chr2:99574642 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.79 -10.2 -0.48 1.69e-21 Chronic sinus infection; LIHC trans rs2727020 0.530 rs7113153 chr11:49457957 G/A cg18944383 chr4:111397179 ENPEP 0.34 7.96 0.4 2.52e-14 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25417551 chr17:35767582 TADA2A;ACACA 0.5 6.89 0.35 2.7e-11 Lung function (FEV1/FVC); LIHC cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg15382696 chr6:118971807 C6orf204 0.62 6.03 0.31 4.36e-9 Renal cell carcinoma; LIHC cis rs16828019 0.777 rs12023079 chr1:41470111 G/A cg03962019 chr1:41807865 NA 0.52 7.06 0.36 9.17e-12 Intelligence (multi-trait analysis); LIHC cis rs970821 1.000 rs17349815 chr8:124746417 C/G cg00283535 chr8:124749564 ANXA13 0.35 5.97 0.31 6.04e-9 Breast cancer; LIHC cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.21 -0.45 3.32e-18 Electroencephalogram traits; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg22528358 chr1:107598549 PRMT6 0.7 11.55 0.53 2.75e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4474465 0.688 rs7942527 chr11:78280322 A/G cg27205649 chr11:78285834 NARS2 0.5 7.88 0.39 4.27e-14 Alzheimer's disease (survival time); LIHC cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg13866156 chr1:1669148 SLC35E2 0.7 13.9 0.6 4.1e-35 Body mass index; LIHC cis rs9790314 1.000 rs1993891 chr3:161047467 A/G cg04691961 chr3:161091175 C3orf57 -0.42 -6.64 -0.34 1.25e-10 Morning vs. evening chronotype; LIHC cis rs950169 0.810 rs62029594 chr15:84955252 T/C cg17507749 chr15:85114479 UBE2QP1 0.73 8.5 0.42 5.84e-16 Schizophrenia; LIHC cis rs13256369 1.000 rs10110591 chr8:8576608 G/T cg00074818 chr8:8560427 CLDN23 -0.34 -5.82 -0.3 1.38e-8 Obesity-related traits; LIHC cis rs10771431 0.597 rs10771413 chr12:9354413 C/T cg08997352 chr12:9597637 DDX12 -0.49 -7.61 -0.38 2.62e-13 Breast size; LIHC cis rs9457247 0.529 rs6907666 chr6:167523395 A/G cg12798992 chr6:167411361 FGFR1OP -0.41 -6.45 -0.33 3.71e-10 Crohn's disease; LIHC cis rs17685 0.558 rs60787921 chr7:75792844 C/A cg04592579 chr7:75616294 TMEM120A 0.41 7.0 0.35 1.33e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7731783 1 rs7731783 chr5:177060312 T/C cg15051221 chr5:177434457 FAM153C 0.33 5.85 0.3 1.16e-8 Methadone dose in opioid dependence; LIHC cis rs477895 0.713 rs2282490 chr11:63962152 T/C cg18225595 chr11:63971243 STIP1 0.68 8.42 0.41 1.04e-15 Mean platelet volume; LIHC cis rs920590 0.758 rs1817836 chr8:19664852 T/C cg03894339 chr8:19674705 INTS10 0.6 9.69 0.46 8.97e-20 Acute lymphoblastic leukemia (childhood); LIHC cis rs2404602 0.530 rs12915184 chr15:76965922 G/A cg03037974 chr15:76606532 NA -0.51 -8.06 -0.4 1.27e-14 Blood metabolite levels; LIHC cis rs892961 0.899 rs3650 chr17:75415835 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.28 0.37 2.24e-12 Airflow obstruction; LIHC cis rs2997447 0.846 rs3008225 chr1:26390181 T/A cg19633962 chr1:26362018 EXTL1 -0.52 -5.89 -0.3 9.2e-9 QRS complex (12-leadsum); LIHC cis rs13118159 0.801 rs10024996 chr4:1328297 G/A cg19318889 chr4:1322082 MAEA 0.44 5.91 0.3 8.3e-9 Longevity; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg00908189 chr16:619842 PIGQ 0.83 13.89 0.6 4.12e-35 Height; LIHC cis rs11958404 0.932 rs11950297 chr5:157419938 T/G cg05962755 chr5:157440814 NA 1.06 11.57 0.53 2.42e-26 IgG glycosylation; LIHC cis rs6570726 0.791 rs9373464 chr6:145907167 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.8 -0.3 1.49e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs473651 0.935 rs541128 chr2:239336449 A/G cg18131467 chr2:239335373 ASB1 1.08 20.83 0.75 8.17e-63 Multiple system atrophy; LIHC cis rs7116495 1.000 rs635442 chr11:71570982 A/G cg26138937 chr11:71823887 C11orf51 0.7 6.64 0.34 1.25e-10 Severe influenza A (H1N1) infection; LIHC cis rs9733 0.519 rs11204717 chr1:150709129 T/A cg15448220 chr1:150897856 SETDB1 0.44 6.84 0.35 3.63e-11 Tonsillectomy; LIHC cis rs72627509 0.857 rs56155140 chr4:57824451 G/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.58 -8.46 -0.42 8.15e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg22168489 chr12:122356033 WDR66 -0.48 -8.05 -0.4 1.36e-14 Mean corpuscular volume; LIHC cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg02290350 chr8:58132656 NA 0.38 7.79 0.39 8.16e-14 Developmental language disorder (linguistic errors); LIHC cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg11764359 chr7:65958608 NA -0.58 -6.05 -0.31 3.88e-9 Diabetic kidney disease; LIHC trans rs7618501 1.000 rs11130221 chr3:49819102 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.82 15.22 0.64 2.68e-40 Intelligence (multi-trait analysis); LIHC cis rs7980687 0.662 rs585522 chr12:123550813 A/G cg05973401 chr12:123451056 ABCB9 0.46 6.21 0.32 1.56e-9 Height;Educational attainment;Head circumference (infant); LIHC cis rs8005677 0.926 rs34344888 chr14:23387585 A/G cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs2816062 0.735 rs2816045 chr1:18892999 A/G cg18795169 chr1:18902165 NA -0.79 -17.48 -0.69 2.43e-49 Urate levels in lean individuals; LIHC cis rs6570726 0.905 rs377143 chr6:145834220 C/T cg23711669 chr6:146136114 FBXO30 0.52 9.22 0.45 3.03e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs72781680 0.716 rs2675363 chr2:24080003 G/C cg08917208 chr2:24149416 ATAD2B 0.65 6.57 0.33 1.84e-10 Lymphocyte counts; LIHC cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.76 0.47 5.3e-20 Platelet count; LIHC cis rs7772486 0.905 rs9373486 chr6:146446024 C/G cg13319975 chr6:146136371 FBXO30 0.41 6.71 0.34 7.86e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1113500 0.836 rs2801220 chr1:108584649 A/G cg06207961 chr1:108661230 NA -0.36 -6.84 -0.35 3.55e-11 Growth-regulated protein alpha levels; LIHC cis rs7902334 1.000 rs7902334 chr10:12645941 A/C cg26169081 chr10:12648338 CAMK1D -0.81 -9.93 -0.47 1.37e-20 Coronary artery aneurysm in Kawasaki disease; LIHC cis rs17270561 1.000 rs17270561 chr6:25820439 A/C cg16482183 chr6:26056742 HIST1H1C -0.5 -5.98 -0.31 5.5e-9 Iron status biomarkers; LIHC cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg06238570 chr21:40685208 BRWD1 0.6 7.23 0.36 3.26e-12 Cognitive function; LIHC cis rs11792861 0.926 rs58795279 chr9:111851902 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.64e-16 Menarche (age at onset); LIHC cis rs7582180 0.676 rs4264577 chr2:100930662 T/C cg14675211 chr2:100938903 LONRF2 0.56 8.7 0.43 1.44e-16 Intelligence (multi-trait analysis); LIHC trans rs801193 1.000 rs3800812 chr7:66223461 T/C cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.81e-11 Aortic root size; LIHC cis rs116095464 0.558 rs6869925 chr5:264036 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg06634786 chr22:41940651 POLR3H -0.82 -9.0 -0.44 1.62e-17 Vitiligo; LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs10876993 0.928 rs10082911 chr12:58104104 C/A cg15848620 chr12:58087721 OS9 -0.55 -7.51 -0.38 5.32e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs11628318 0.591 rs8010679 chr14:103155637 T/G cg01864069 chr14:103024347 NA 0.37 6.21 0.32 1.53e-9 Platelet count; LIHC cis rs1707322 0.721 rs11211165 chr1:46157906 C/T cg03146154 chr1:46216737 IPP 0.6 10.26 0.49 1.04e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6835098 1.000 rs1054497 chr4:174089048 A/T cg27433088 chr4:174089019 GALNT7 -0.39 -7.21 -0.36 3.67e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg26338869 chr17:61819248 STRADA 0.6 8.75 0.43 9.91e-17 Prudent dietary pattern; LIHC cis rs611744 0.870 rs650925 chr8:109196725 T/C cg21045802 chr8:109455806 TTC35 0.59 9.9 0.47 1.7e-20 Dupuytren's disease; LIHC cis rs1008375 0.931 rs1860592 chr4:17577028 C/G cg02297831 chr4:17616191 MED28 0.48 7.28 0.37 2.31e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs921968 0.612 rs2384950 chr2:219499719 T/C cg02985541 chr2:219472218 PLCD4 0.4 7.38 0.37 1.23e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs963731 0.649 rs10153761 chr2:39262068 C/T cg04010122 chr2:39346883 SOS1 -0.68 -6.11 -0.31 2.73e-9 Corticobasal degeneration; LIHC cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg11890956 chr21:40555474 PSMG1 1.07 15.54 0.64 1.36e-41 Cognitive function; LIHC cis rs853679 0.517 rs9368553 chr6:28082265 T/C cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg18252515 chr7:66147081 NA 1.29 17.34 0.68 9.06e-49 Diabetic kidney disease; LIHC cis rs9816226 0.591 rs6809651 chr3:185814642 G/A cg00760338 chr3:185826511 ETV5 -0.68 -5.71 -0.3 2.46e-8 Obesity;Body mass index; LIHC cis rs7129556 0.539 rs6592728 chr11:77247260 A/G cg03570279 chr11:77446074 RSF1 -0.35 -6.44 -0.33 4.08e-10 Weight loss (gastric bypass surgery); LIHC cis rs9419702 0.568 rs7075233 chr10:133545170 A/G cg04492858 chr10:133558786 NA -0.44 -6.51 -0.33 2.74e-10 Survival in rectal cancer; LIHC cis rs1799949 0.965 rs799912 chr17:41257134 T/C cg23758822 chr17:41437982 NA 0.96 18.38 0.7 6.07e-53 Menopause (age at onset); LIHC cis rs864537 0.622 rs1214598 chr1:167426424 C/T cg22356347 chr1:167427500 CD247 -0.4 -6.64 -0.34 1.24e-10 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs4268898 0.662 rs72795824 chr2:24435837 T/C cg06627628 chr2:24431161 ITSN2 -0.73 -9.61 -0.46 1.67e-19 Asthma; LIHC cis rs10504229 0.679 rs4737454 chr8:58033965 A/T cg02290350 chr8:58132656 NA 0.31 7.17 0.36 4.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs3790844 0.876 rs3790845 chr1:200006861 C/T cg13229857 chr1:200006247 NR5A2 0.44 7.19 0.36 4.2e-12 Pancreatic cancer; LIHC cis rs6500602 0.702 rs6500605 chr16:4502410 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.47 7.42 0.37 9.63e-13 Schizophrenia; LIHC cis rs1577917 1.000 rs12201735 chr6:86656939 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.89 -0.35 2.68e-11 Response to antipsychotic treatment; LIHC cis rs7613875 0.641 rs6793528 chr3:50100188 C/A cg24110177 chr3:50126178 RBM5 0.56 9.16 0.44 4.94e-18 Body mass index; LIHC trans rs10411161 1.000 rs6509581 chr19:52363882 T/C cg22319618 chr22:45562946 NUP50 -0.51 -6.91 -0.35 2.31e-11 Breast cancer; LIHC cis rs1113500 0.933 rs12035689 chr1:108636756 T/C cg06207961 chr1:108661230 NA 0.38 7.38 0.37 1.2e-12 Growth-regulated protein alpha levels; LIHC cis rs6570726 0.818 rs437978 chr6:145809134 A/G cg23711669 chr6:146136114 FBXO30 0.57 10.14 0.48 2.62e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs9318086 0.712 rs1886970 chr13:24440498 T/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.56 11.08 0.51 1.42e-24 Myopia (pathological); LIHC trans rs12960119 0.536 rs12964768 chr18:23742176 C/T cg05333146 chr16:67183725 B3GNT9 0.64 6.09 0.31 3e-9 Rhegmatogenous retinal detachment; LIHC cis rs11122272 0.735 rs2437147 chr1:231516756 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs11676348 0.846 rs6723449 chr2:218997580 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.44 6.25 0.32 1.22e-9 Ulcerative colitis; LIHC cis rs3540 0.597 rs1978151 chr15:91037300 C/T cg22089800 chr15:90895588 ZNF774 0.6 8.04 0.4 1.47e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs7633770 0.710 rs11710586 chr3:46693457 A/G cg11219411 chr3:46661640 NA -0.42 -7.23 -0.36 3.13e-12 Coronary artery disease; LIHC cis rs2997447 0.846 rs55912918 chr1:26409801 C/T cg19633962 chr1:26362018 EXTL1 -0.69 -6.29 -0.32 9.47e-10 QRS complex (12-leadsum); LIHC cis rs2933343 0.679 rs789221 chr3:128591625 A/G cg25356066 chr3:128598488 ACAD9 0.56 7.75 0.39 1.08e-13 IgG glycosylation; LIHC trans rs4332037 1.000 rs62442899 chr7:1948454 C/T cg11693508 chr17:37793320 STARD3 0.73 7.52 0.38 4.76e-13 Bipolar disorder; LIHC cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg13047869 chr3:10149882 C3orf24 0.5 6.08 0.31 3.23e-9 Alzheimer's disease; LIHC cis rs9303401 1.000 rs9904677 chr17:56873025 A/G cg25039879 chr17:56429692 SUPT4H1 0.52 7.28 0.37 2.29e-12 Cognitive test performance; LIHC cis rs16866061 0.962 rs16866045 chr2:225413020 G/A cg12698349 chr2:225449008 CUL3 0.81 14.11 0.61 5.84e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs1215050 0.791 rs2695472 chr4:98855127 T/C cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.61e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4925386 1.000 rs6121990 chr20:60919263 G/A cg03945807 chr20:60948434 NA -0.36 -6.49 -0.33 2.93e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg00091569 chr3:40428383 ENTPD3 0.39 6.57 0.33 1.89e-10 Renal cell carcinoma; LIHC cis rs116248771 0.739 rs12488447 chr3:158421824 T/C cg16708174 chr3:158430962 RARRES1 0.47 6.25 0.32 1.25e-9 diarrhoeal disease at age 2; LIHC cis rs9649213 0.593 rs62478177 chr7:97964611 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs72627509 0.904 rs12645070 chr4:57770106 G/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.55 -7.83 -0.39 6.02e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg18252515 chr7:66147081 NA 1.28 17.42 0.69 4.2e-49 Diabetic kidney disease; LIHC cis rs17826219 0.500 rs2449749 chr17:29078298 C/T cg14067834 chr17:29058358 SUZ12P 0.68 6.69 0.34 9.29e-11 Body mass index; LIHC cis rs67311347 1.000 rs2305521 chr3:40429183 A/G cg16822855 chr3:40428330 ENTPD3 0.34 6.24 0.32 1.26e-9 Renal cell carcinoma; LIHC cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg11890956 chr21:40555474 PSMG1 1.06 15.39 0.64 5.35e-41 Cognitive function; LIHC cis rs4845570 0.920 rs6694952 chr1:151760131 T/C cg07092448 chr1:151763213 TDRKH 0.69 7.8 0.39 7.82e-14 Coronary artery disease; LIHC cis rs9916302 0.904 rs35335692 chr17:37710006 A/G cg00129232 chr17:37814104 STARD3 -0.41 -6.52 -0.33 2.47e-10 Glomerular filtration rate (creatinine); LIHC cis rs7937890 0.560 rs2597194 chr11:14497269 C/T cg02886208 chr11:14281011 SPON1 -0.49 -6.56 -0.33 1.94e-10 Mitochondrial DNA levels; LIHC cis rs4665809 1.000 rs12469163 chr2:26283587 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.73 -8.95 -0.44 2.26e-17 Gut microbiome composition (summer); LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg11905131 chr22:24372483 LOC391322 -0.73 -10.94 -0.51 4.49e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9902453 0.740 rs2254414 chr17:28061130 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.33 -0.58 6.42e-33 Coffee consumption (cups per day); LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg20302342 chr1:156215951 PAQR6 0.32 6.18 0.32 1.83e-9 Tonsillectomy; LIHC cis rs1552244 0.554 rs2272118 chr3:10049287 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.67 0.38 1.83e-13 Alzheimer's disease; LIHC cis rs8081395 0.769 rs12449331 chr17:57883646 T/C cg13753209 chr17:57696993 CLTC -0.47 -7.33 -0.37 1.63e-12 White blood cell count; LIHC trans rs17185553 1.000 rs17185553 chr9:17934120 C/G cg11549972 chr12:103358649 NA 0.61 6.15 0.32 2.21e-9 Small cell lung carcinoma; LIHC cis rs992157 0.731 rs1399132 chr2:219159770 G/A cg00012203 chr2:219082015 ARPC2 0.85 13.91 0.6 3.46e-35 Colorectal cancer; LIHC cis rs2806561 1.000 rs2806563 chr1:23506625 C/T cg19743168 chr1:23544995 NA -0.38 -7.09 -0.36 7.69e-12 Height; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.71 -0.34 8.16e-11 Total body bone mineral density; LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg00656387 chr3:40428638 ENTPD3 0.5 8.29 0.41 2.68e-15 Renal cell carcinoma; LIHC cis rs7552404 0.731 rs1770885 chr1:76402212 C/T cg10523679 chr1:76189770 ACADM -0.58 -6.91 -0.35 2.43e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9457247 0.602 rs17615336 chr6:167506734 A/G cg12798992 chr6:167411361 FGFR1OP 0.45 6.63 0.34 1.3e-10 Crohn's disease; LIHC trans rs11098499 0.564 rs11098507 chr4:120288286 G/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs9549328 0.837 rs4907572 chr13:113647321 G/A cg08528486 chr13:113648767 MCF2L -0.4 -6.39 -0.33 5.57e-10 Systolic blood pressure; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg21668880 chr6:34759629 UHRF1BP1 -0.46 -6.35 -0.32 6.88e-10 Lung cancer in ever smokers; LIHC cis rs1506636 1.000 rs2402671 chr7:123355483 T/C cg03229431 chr7:123269106 ASB15 -0.59 -11.97 -0.54 8.22e-28 Plateletcrit;Platelet count; LIHC trans rs9951602 0.512 rs9952372 chr18:76656295 A/G cg02800362 chr5:177631904 HNRNPAB 0.65 10.23 0.48 1.33e-21 Obesity-related traits; LIHC cis rs9768139 0.733 rs10156158 chr7:158122287 G/T cg06219351 chr7:158114137 PTPRN2 -0.21 -5.85 -0.3 1.15e-8 Calcium levels; LIHC cis rs1198872 0.526 rs57282335 chr2:10928207 G/A cg15705551 chr2:10952987 PDIA6 0.71 9.92 0.47 1.52e-20 Cardiac Troponin-T levels; LIHC cis rs77637988 0.578 rs7576964 chr2:48601448 G/T cg15846641 chr2:48541264 FOXN2 0.59 7.98 0.4 2.18e-14 Joint mobility (Beighton score); LIHC cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg24531977 chr5:56204891 C5orf35 -0.59 -8.42 -0.41 1.08e-15 Initial pursuit acceleration; LIHC cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg12463550 chr7:65579703 CRCP 0.73 7.64 0.38 2.26e-13 Diabetic kidney disease; LIHC cis rs17106184 0.892 rs72900922 chr1:51095195 G/A cg07174182 chr1:51127561 FAF1 -0.65 -7.04 -0.36 1.03e-11 Type 2 diabetes; LIHC cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg06453172 chr10:134556979 INPP5A -0.62 -7.78 -0.39 8.5e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12477438 1.000 rs1922624 chr2:99909958 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -7.66 -0.38 1.99e-13 Chronic sinus infection; LIHC cis rs4908768 0.501 rs6577494 chr1:8576925 C/T cg20416874 chr1:8611966 RERE -0.68 -14.62 -0.62 6.18e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg10150615 chr22:24372951 LOC391322 0.58 8.22 0.41 4.31e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1129187 0.748 rs6458312 chr6:42904274 G/T cg05552183 chr6:42928497 GNMT 0.42 5.94 0.31 6.96e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs10744422 1.000 rs7139055 chr12:123364198 A/G cg22842854 chr12:123319900 HIP1R 0.66 8.14 0.4 7.2e-15 Schizophrenia; LIHC cis rs2797160 0.967 rs2747718 chr6:126009109 C/A cg05901451 chr6:126070800 HEY2 0.45 7.44 0.37 8.16e-13 Endometrial cancer; LIHC cis rs1801251 1.000 rs7578299 chr2:233573469 G/T cg08000102 chr2:233561755 GIGYF2 0.75 11.28 0.52 2.61e-25 Coronary artery disease; LIHC cis rs6783573 0.535 rs6442006 chr3:46629382 C/G cg16875182 chr3:46619291 LRRC2;TDGF1 -0.6 -6.64 -0.34 1.2e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg21171335 chr12:122356390 WDR66 -0.46 -7.5 -0.38 5.45e-13 Mean corpuscular volume; LIHC cis rs10256972 0.706 rs12701969 chr7:1121849 A/G cg04025307 chr7:1156635 C7orf50 0.6 10.28 0.49 8.9e-22 Longevity;Endometriosis; LIHC cis rs7824557 0.592 rs2736280 chr8:11223022 C/A cg21775007 chr8:11205619 TDH 0.57 8.43 0.41 9.64e-16 Retinal vascular caliber; LIHC cis rs11112613 0.609 rs11112632 chr12:106041887 A/G cg03607813 chr12:105948248 NA -0.49 -7.8 -0.39 7.76e-14 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs9640161 0.742 rs2159235 chr7:150017228 T/C cg10018233 chr7:150070692 REPIN1 0.54 9.2 0.45 3.73e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs12130219 0.500 rs4845743 chr1:152184149 A/G cg03465714 chr1:152285911 FLG -0.31 -6.21 -0.32 1.56e-9 Inflammatory skin disease; LIHC cis rs10197940 0.686 rs12616688 chr2:152242099 C/G cg06191203 chr2:152266755 RIF1 -0.43 -7.44 -0.37 8.11e-13 Lung cancer; LIHC cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg18357526 chr6:26021779 HIST1H4A 1.0 14.47 0.62 2.44e-37 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.647 rs4904673 chr14:90817338 G/A cg14092571 chr14:90743983 NA 0.42 5.77 0.3 1.8e-8 Mortality in heart failure; LIHC cis rs12477438 0.798 rs6704766 chr2:99642818 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.41 -0.53 8.75e-26 Chronic sinus infection; LIHC cis rs4803468 1.000 rs2304242 chr19:41944616 G/T cg14132834 chr19:41945861 ATP5SL 0.45 6.61 0.34 1.5e-10 Height; LIHC cis rs2832191 0.636 rs8131295 chr21:30516819 A/T cg08807101 chr21:30365312 RNF160 -0.44 -6.29 -0.32 9.94e-10 Dental caries; LIHC cis rs6089829 0.925 rs3746748 chr20:61667526 C/T cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs5769765 0.658 rs2157536 chr22:50190180 G/A cg02269571 chr22:50332266 NA -0.59 -8.06 -0.4 1.28e-14 Schizophrenia; LIHC cis rs72653721 0.713 rs60197525 chr6:11053289 T/C cg13562911 chr6:11044106 ELOVL2 0.52 7.41 0.37 1.03e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17164693 chr10:124913828 BUB3 0.51 7.15 0.36 5.2e-12 Pancreatic cancer; LIHC cis rs9322817 0.691 rs12203954 chr6:105295647 C/T cg02098413 chr6:105308735 HACE1 0.44 8.33 0.41 1.92e-15 Thyroid stimulating hormone; LIHC cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg25072359 chr17:41440525 NA 0.37 5.84 0.3 1.2e-8 Menopause (age at onset); LIHC trans rs72960926 0.744 rs72954341 chr6:74947167 A/G cg07247405 chr1:2484626 LOC115110 0.53 6.41 0.33 4.83e-10 Metabolite levels (MHPG); LIHC cis rs6952808 0.601 rs3778978 chr7:2159817 A/G cg21782813 chr7:2030301 MAD1L1 0.38 6.5 0.33 2.77e-10 Bipolar disorder and schizophrenia; LIHC cis rs11711311 0.955 rs12636240 chr3:113391282 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.36 6.1 0.31 2.84e-9 IgG glycosylation; LIHC cis rs172166 0.611 rs203883 chr6:28078356 A/G cg23485639 chr6:28045615 ZNF165 0.4 6.3 0.32 9.03e-10 Cardiac Troponin-T levels; LIHC cis rs151997 0.569 rs62367393 chr5:50270360 C/A cg06027927 chr5:50259733 NA 0.54 6.61 0.34 1.46e-10 Callous-unemotional behaviour; LIHC cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg21724239 chr8:58056113 NA 0.48 6.28 0.32 1.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg22903471 chr2:27725779 GCKR -0.45 -7.77 -0.39 9.52e-14 Total body bone mineral density; LIHC cis rs7044106 0.791 rs2416797 chr9:123480600 C/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 10.95 0.51 3.9e-24 Hip circumference adjusted for BMI; LIHC cis rs2012796 0.661 rs59969857 chr14:81841579 A/G cg02996355 chr14:81879375 NA 0.7 11.42 0.53 8.24e-26 Night sleep phenotypes; LIHC cis rs1144333 0.655 rs17097681 chr1:76376926 C/T cg22875332 chr1:76189707 ACADM 0.41 6.03 0.31 4.24e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs801193 0.660 rs2659914 chr7:66156914 C/T cg18252515 chr7:66147081 NA -0.44 -6.38 -0.33 5.68e-10 Aortic root size; LIHC cis rs10751667 1.000 rs7396366 chr11:986185 C/A cg06064525 chr11:970664 AP2A2 -0.5 -12.26 -0.55 7.1e-29 Alzheimer's disease (late onset); LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg11494091 chr17:61959527 GH2 0.36 6.09 0.31 2.96e-9 Height; LIHC cis rs4843747 0.605 rs28399183 chr16:88107277 G/A cg00677901 chr16:88017247 BANP 0.52 8.02 0.4 1.74e-14 Menopause (age at onset); LIHC cis rs7520050 0.966 rs7539932 chr1:46292354 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.08 0.31 3.26e-9 Red blood cell count;Reticulocyte count; LIHC cis rs853679 0.517 rs9368556 chr6:28131153 T/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs10504073 0.669 rs341809 chr8:50042557 C/T cg00325661 chr8:49890786 NA 0.32 6.96 0.35 1.76e-11 Blood metabolite ratios; LIHC cis rs11792861 0.926 rs1044905 chr9:111781495 G/A cg13535736 chr9:111863775 C9orf5 -0.41 -6.26 -0.32 1.14e-9 Menarche (age at onset); LIHC cis rs904251 0.523 rs2797799 chr6:37483620 T/G cg08126542 chr6:37504118 NA -0.36 -6.24 -0.32 1.29e-9 Cognitive performance; LIHC cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg07061783 chr6:25882402 NA -0.53 -6.99 -0.35 1.42e-11 Intelligence (multi-trait analysis); LIHC trans rs637571 0.654 rs1058068 chr11:65667796 G/A cg17712092 chr4:129076599 LARP1B 0.9 16.74 0.67 2.29e-46 Eosinophil percentage of white cells; LIHC cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg05665937 chr4:1216051 CTBP1 0.45 6.0 0.31 4.97e-9 Obesity-related traits; LIHC cis rs12291225 0.585 rs10832242 chr11:14340504 C/T cg19336497 chr11:14380999 RRAS2 0.67 14.18 0.61 3.14e-36 Sense of smell; LIHC cis rs7614311 0.689 rs73122704 chr3:63841228 C/T cg22134162 chr3:63841271 THOC7 -0.55 -6.33 -0.32 7.83e-10 Lung function (FVC);Lung function (FEV1); LIHC trans rs6952808 0.929 rs11761270 chr7:1923695 C/T cg04565464 chr8:145669602 NFKBIL2 0.39 6.26 0.32 1.17e-9 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.862 rs778702 chr7:65864835 G/A cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs9457247 0.582 rs9459855 chr6:167466150 G/T cg12798992 chr6:167411361 FGFR1OP 0.45 6.75 0.34 6.53e-11 Crohn's disease; LIHC cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg22974920 chr21:40686053 BRWD1 -0.4 -5.78 -0.3 1.66e-8 Cognitive function; LIHC cis rs17711722 0.583 rs10085415 chr7:65093568 T/A cg18876405 chr7:65276391 NA -0.56 -9.43 -0.45 6.31e-19 Calcium levels; LIHC cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg16262614 chr3:133464971 TF 0.28 6.48 0.33 3.29e-10 Iron status biomarkers; LIHC cis rs7582720 1.000 rs72932566 chr2:203855342 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.1 0.31 2.88e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs735860 0.712 rs3736732 chr6:53160383 G/T cg10236188 chr6:53219634 NA -0.41 -7.35 -0.37 1.5e-12 Glaucoma; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg01287788 chr2:86362935 SNORD94;PTCD3 -0.5 -6.11 -0.31 2.73e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs12477438 0.520 rs4588238 chr2:99749350 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.8 0.65 1.35e-42 Chronic sinus infection; LIHC cis rs2832077 0.527 rs9981922 chr21:30212718 A/G cg08807101 chr21:30365312 RNF160 -0.56 -7.72 -0.39 1.31e-13 Cognitive test performance; LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg08677398 chr8:58056175 NA 0.38 5.73 0.3 2.21e-8 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16164276 chr3:11034345 SLC6A1 0.41 6.69 0.34 8.91e-11 Pancreatic cancer; LIHC trans rs17685 0.753 rs10233282 chr7:75790081 C/T cg19862616 chr7:65841803 NCRNA00174 0.94 19.29 0.72 1.3e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11122272 0.735 rs2491405 chr1:231513431 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs34779708 0.966 rs2505639 chr10:35474421 A/G cg03585969 chr10:35415529 CREM -0.77 -11.54 -0.53 2.94e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2228479 0.717 rs34027607 chr16:89808939 T/C cg19635926 chr16:89946313 TCF25 0.46 6.0 0.31 5.11e-9 Skin colour saturation; LIHC cis rs921968 0.607 rs529474 chr2:219463283 C/T cg18887096 chr2:219472410 PLCD4 0.37 6.39 0.33 5.47e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs950776 0.518 rs952215 chr15:78819153 C/T cg06917634 chr15:78832804 PSMA4 -0.93 -14.33 -0.61 8.5e-37 Sudden cardiac arrest; LIHC cis rs7927592 1.000 rs7927592 chr11:68369960 G/A cg16797656 chr11:68205561 LRP5 0.5 7.78 0.39 8.81e-14 Total body bone mineral density; LIHC cis rs11711311 1.000 rs10212375 chr3:113471336 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.26 -0.37 2.56e-12 IgG glycosylation; LIHC cis rs4930103 0.935 rs2075744 chr11:2018449 A/G cg06197492 chr11:2016605 H19 0.37 6.0 0.31 5.05e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs11690935 0.550 rs6730085 chr2:172864845 C/A cg13550731 chr2:172543902 DYNC1I2 0.41 6.18 0.32 1.82e-9 Schizophrenia; LIHC cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.99 0.51 2.87e-24 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08436942 chr4:4249992 TMEM128 0.48 6.39 0.33 5.36e-10 Lung function (FEV1/FVC); LIHC cis rs8081395 0.899 rs2645477 chr17:57845624 A/C cg13753209 chr17:57696993 CLTC -0.46 -7.02 -0.35 1.23e-11 White blood cell count; LIHC cis rs7149337 0.804 rs4131981 chr14:51667504 A/T cg23942311 chr14:51606299 NA -0.32 -6.2 -0.32 1.58e-9 Cancer; LIHC cis rs734999 0.545 rs4648356 chr1:2709164 C/A cg18854424 chr1:2615690 NA 0.32 7.07 0.36 8.53e-12 Ulcerative colitis; LIHC trans rs2211698 1.000 rs1003532 chr21:35834630 C/T cg18044562 chr7:50468399 IKZF1 -0.5 -7.14 -0.36 5.74e-12 Cancer; LIHC cis rs9814567 0.752 rs9848254 chr3:134330374 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2637266 1.000 rs2395387 chr10:78357029 T/C cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs3008870 0.755 rs2815381 chr1:67514591 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.52 8.86 0.43 4.51e-17 Lymphocyte percentage of white cells; LIHC cis rs11077998 0.967 rs4789782 chr17:80489323 G/T cg10255544 chr17:80519551 FOXK2 -0.49 -9.01 -0.44 1.44e-17 Reticulocyte fraction of red cells; LIHC trans rs11689435 0.925 rs1478591 chr2:218346062 A/T cg13544946 chr9:35729779 TLN1 -0.44 -6.35 -0.32 6.82e-10 Metabolite levels (MHPG); LIHC cis rs1003719 0.788 rs7277657 chr21:38469523 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg00106254 chr7:1943704 MAD1L1 -0.48 -8.05 -0.4 1.38e-14 Bipolar disorder and schizophrenia; LIHC trans rs9914544 0.545 rs2892015 chr17:18786849 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.57 -0.33 1.82e-10 Educational attainment (years of education); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17059624 chr11:85358760 TMEM126A 0.49 6.82 0.35 4.2e-11 Pancreatic cancer; LIHC cis rs3812049 0.737 rs790155 chr5:127498380 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.46 5.74 0.3 2.14e-8 Lymphocyte counts;Red cell distribution width; LIHC cis rs9473924 0.618 rs61236902 chr6:50813055 C/G cg14470998 chr6:50812995 TFAP2B 0.98 11.12 0.52 9.6e-25 Body mass index; LIHC cis rs1448094 0.511 rs10863083 chr12:86226739 C/A cg02569458 chr12:86230093 RASSF9 0.45 6.07 0.31 3.43e-9 Major depressive disorder; LIHC cis rs801193 0.591 rs2707839 chr7:66193084 A/G cg18252515 chr7:66147081 NA -0.43 -6.3 -0.32 9.36e-10 Aortic root size; LIHC cis rs73001065 0.792 rs17216525 chr19:19662220 C/T cg03709012 chr19:19516395 GATAD2A 0.92 7.94 0.39 3.03e-14 LDL cholesterol; LIHC cis rs7674212 0.510 rs2720468 chr4:104085153 A/G cg16532752 chr4:104119610 CENPE -0.43 -6.75 -0.34 6.31e-11 Type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06157335 chr1:53164003 C1orf163 0.4 6.25 0.32 1.19e-9 Pancreatic cancer; LIHC cis rs986417 1.000 rs8021348 chr14:60952777 G/T cg27398547 chr14:60952738 C14orf39 0.82 9.57 0.46 2.22e-19 Gut microbiota (bacterial taxa); LIHC cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.05 -0.31 3.74e-9 Colorectal cancer; LIHC cis rs7116495 1.000 rs949325 chr11:71729656 A/G cg10381502 chr11:71823885 C11orf51 -0.54 -5.78 -0.3 1.73e-8 Severe influenza A (H1N1) infection; LIHC cis rs11792861 0.926 rs3750451 chr9:111822866 C/T cg13535736 chr9:111863775 C9orf5 -0.4 -5.99 -0.31 5.37e-9 Menarche (age at onset); LIHC cis rs6714710 0.627 rs6748124 chr2:98519014 T/C cg26665480 chr2:98280029 ACTR1B 0.44 6.2 0.32 1.64e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs16866061 0.515 rs3738951 chr2:225368321 A/G cg22509189 chr2:225307070 NA -0.5 -7.42 -0.37 9.6e-13 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs116095464 0.558 rs9687898 chr5:253952 A/G cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC trans rs4714291 0.775 rs2949019 chr6:40051200 C/T cg02267698 chr19:7991119 CTXN1 -0.42 -7.22 -0.36 3.34e-12 Strep throat; LIHC cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg26119090 chr2:26468346 HADHA;HADHB 1.11 17.32 0.68 1.1e-48 Gut microbiome composition (summer); LIHC cis rs7552404 1.000 rs7516226 chr1:76234257 G/A cg10523679 chr1:76189770 ACADM 0.65 8.72 0.43 1.2e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7903847 0.642 rs11189174 chr10:99139600 C/G cg20016023 chr10:99160130 RRP12 -0.42 -6.64 -0.34 1.24e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1707322 0.685 rs6690926 chr1:46134978 T/C cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg12648201 chr2:27665141 KRTCAP3 -0.41 -5.75 -0.3 1.93e-8 Total body bone mineral density; LIHC trans rs11098499 0.954 rs10017543 chr4:120321420 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.76 0.47 5.25e-20 Corneal astigmatism; LIHC cis rs7091068 0.659 rs10732241 chr10:95468573 T/C cg20715218 chr10:95462985 C10orf4 0.59 6.61 0.34 1.45e-10 Urinary tract infection frequency; LIHC cis rs12701220 0.696 rs12112029 chr7:1137889 G/A cg09177884 chr7:1199841 ZFAND2A -0.53 -6.2 -0.32 1.61e-9 Bronchopulmonary dysplasia; LIHC cis rs3008870 1.000 rs3008871 chr1:67419089 A/G cg02640540 chr1:67518911 SLC35D1 -0.49 -6.49 -0.33 3.08e-10 Lymphocyte percentage of white cells; LIHC cis rs4975616 0.836 rs421629 chr5:1320136 G/A cg06550200 chr5:1325588 CLPTM1L -0.67 -10.35 -0.49 5.02e-22 Lung cancer; LIHC cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.46 6.17 0.32 1.88e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs1814175 0.817 rs7924619 chr11:49620632 G/A cg18944383 chr4:111397179 ENPEP 0.24 6.13 0.31 2.47e-9 Height; LIHC cis rs780096 0.546 rs715325 chr2:27725572 C/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -6.11 -0.31 2.68e-9 Total body bone mineral density; LIHC cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg04944784 chr2:26401820 FAM59B 0.72 9.25 0.45 2.57e-18 Gut microbiome composition (summer); LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg16132339 chr22:24313637 DDTL;DDT 0.58 9.69 0.46 8.53e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg06212747 chr3:49208901 KLHDC8B 0.66 9.15 0.44 5.21e-18 Menarche (age at onset); LIHC cis rs240764 0.817 rs11155610 chr6:101170233 T/C cg09795085 chr6:101329169 ASCC3 -0.52 -7.21 -0.36 3.65e-12 Neuroticism; LIHC cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg11890956 chr21:40555474 PSMG1 -0.57 -9.5 -0.46 3.65e-19 Cognitive function; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg06873352 chr17:61820015 STRADA 0.75 13.35 0.59 5.02e-33 Prudent dietary pattern; LIHC cis rs7666738 0.570 rs10032272 chr4:99095601 T/C cg05340658 chr4:99064831 C4orf37 0.64 11.27 0.52 2.99e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs6598163 0.564 rs12319878 chr12:132289989 C/T cg10319629 chr12:132285459 NA 0.46 8.2 0.41 5.07e-15 Migraine; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05352688 chr1:211643515 NA 0.18 6.12 0.31 2.63e-9 Cognitive function; LIHC cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg23205692 chr1:25664452 TMEM50A 0.38 6.1 0.31 2.86e-9 Plateletcrit;Mean corpuscular volume; LIHC cis rs6088580 0.634 rs6142159 chr20:32993035 G/A cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg07133347 chr1:107600762 PRMT6 -0.45 -6.8 -0.35 4.69e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1577917 0.958 rs13219504 chr6:86556917 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.22 -0.52 4.4e-25 Response to antipsychotic treatment; LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg06497051 chr1:156261200 TMEM79 0.38 6.09 0.31 3.04e-9 Tonsillectomy; LIHC cis rs763121 0.962 rs6001159 chr22:38966487 A/G cg21395723 chr22:39101663 GTPBP1 0.36 6.11 0.31 2.71e-9 Menopause (age at onset); LIHC cis rs743757 0.938 rs2282753 chr3:50436716 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.7 0.38 1.45e-13 Diastolic blood pressure; LIHC cis rs7618501 0.602 rs2071207 chr3:50159844 T/C cg24110177 chr3:50126178 RBM5 0.53 8.65 0.42 1.97e-16 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.894 rs2600660 chr2:61549600 G/T cg14146966 chr2:61757674 XPO1 -0.44 -7.4 -0.37 1.08e-12 Tuberculosis; LIHC trans rs2243480 0.901 rs34807232 chr7:65965133 G/A cg10756647 chr7:56101905 PSPH 1.03 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs4423214 1.000 rs2282620 chr11:71183477 C/T cg24826892 chr11:71159390 DHCR7 0.47 6.17 0.32 1.91e-9 Vitamin D levels; LIHC cis rs8072100 1.000 rs11650372 chr17:45721795 G/A cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.36 -5.92 -0.3 8.05e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs412000 0.507 rs2680688 chr17:56450524 T/C cg02118635 chr17:56770003 RAD51C;TEX14 -0.47 -6.46 -0.33 3.62e-10 Primary tooth development (time to first tooth eruption); LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg11494091 chr17:61959527 GH2 0.43 7.99 0.4 2.16e-14 Prudent dietary pattern; LIHC cis rs8180040 0.726 rs4682844 chr3:46982737 T/C cg02527881 chr3:46936655 PTH1R 0.35 6.78 0.34 5.38e-11 Colorectal cancer; LIHC cis rs5769765 0.818 rs8140681 chr22:50292081 C/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.16 -0.44 4.85e-18 Schizophrenia; LIHC cis rs250677 0.687 rs2915809 chr5:148452111 A/T cg18129178 chr5:148520854 ABLIM3 -0.48 -7.45 -0.37 7.81e-13 Breast cancer; LIHC cis rs853679 0.517 rs4713141 chr6:28101678 G/C cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs7903847 0.642 rs3814553 chr10:99155984 G/A cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1200821 0.529 rs4934856 chr10:37807847 T/C cg25427524 chr10:38739819 LOC399744 0.45 7.63 0.38 2.35e-13 Hemostatic factors and hematological phenotypes; LIHC cis rs400736 0.930 rs225100 chr1:8066914 C/T cg25007680 chr1:8021821 PARK7 -0.57 -8.98 -0.44 1.88e-17 Response to antidepressants and depression; LIHC cis rs9303401 1.000 rs7218362 chr17:56888299 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.43 6.44 0.33 4.13e-10 Cognitive test performance; LIHC cis rs875971 0.862 rs1860469 chr7:66106875 A/G cg18252515 chr7:66147081 NA 0.48 7.05 0.36 9.79e-12 Aortic root size; LIHC cis rs1401454 1.000 rs1837095 chr11:16245692 T/A cg10927848 chr11:16298618 SOX6 -0.33 -6.08 -0.31 3.24e-9 Blood pressure; LIHC cis rs6952808 0.931 rs7810038 chr7:1894116 T/C cg20295408 chr7:1910781 MAD1L1 -0.51 -7.44 -0.37 8.36e-13 Bipolar disorder and schizophrenia; LIHC cis rs2439831 0.717 rs28495368 chr15:43895642 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.68 9.51 0.46 3.53e-19 Lung cancer in ever smokers; LIHC cis rs9911578 1.000 rs12952832 chr17:56906254 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.85 -0.43 4.75e-17 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg00149659 chr3:10157352 C3orf10 0.63 6.87 0.35 2.99e-11 Alzheimer's disease; LIHC cis rs933688 1.000 rs6869717 chr5:90694797 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 19.73 0.73 2.23e-58 Smoking behavior; LIHC cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg21724239 chr8:58056113 NA 0.57 7.02 0.35 1.22e-11 Developmental language disorder (linguistic errors); LIHC cis rs6545883 0.894 rs10177303 chr2:61594459 G/A cg15711740 chr2:61764176 XPO1 0.42 5.76 0.3 1.89e-8 Tuberculosis; LIHC cis rs6502050 0.764 rs35713597 chr17:80119016 C/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg26338869 chr17:61819248 STRADA -0.52 -6.89 -0.35 2.62e-11 Height; LIHC trans rs1973993 1.000 rs1973993 chr1:96943994 A/G cg10631902 chr5:14652156 NA 0.29 6.52 0.33 2.51e-10 Weight; LIHC cis rs12451471 0.667 rs12942002 chr17:78101629 C/G cg06718696 chr17:78121285 EIF4A3 1.02 11.85 0.54 2.29e-27 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.669 rs11040473 chr11:49703813 C/T cg18944383 chr4:111397179 ENPEP 0.24 6.29 0.32 9.86e-10 Height; LIHC cis rs7223966 1.000 rs8067431 chr17:61817048 T/C cg05941027 chr17:61774174 LIMD2 0.37 7.85 0.39 5.23e-14 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs11792861 0.926 rs7470160 chr9:111844246 C/A cg05043794 chr9:111880884 C9orf5 -0.31 -7.24 -0.36 3.07e-12 Menarche (age at onset); LIHC cis rs3762637 0.943 rs10439995 chr3:122189160 C/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC trans rs2243480 1.000 rs6460274 chr7:65628484 T/A cg10756647 chr7:56101905 PSPH -1.1 -13.4 -0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs67478160 0.608 rs34066659 chr14:104263427 A/C cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.52 -0.38 4.84e-13 Schizophrenia; LIHC trans rs459571 0.959 rs408307 chr9:136892523 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 0.59 9.23 0.45 2.94e-18 Platelet distribution width; LIHC cis rs6430585 0.583 rs76097170 chr2:136593498 C/T cg07169764 chr2:136633963 MCM6 1.04 15.79 0.65 1.47e-42 Corneal structure; LIHC cis rs7086627 0.515 rs1870147 chr10:82212541 A/T cg00277334 chr10:82204260 NA -0.86 -14.43 -0.62 3.52e-37 Post bronchodilator FEV1; LIHC cis rs9649213 0.533 rs62478235 chr7:98030349 G/C cg09267113 chr7:98030324 BAIAP2L1 -0.55 -9.55 -0.46 2.49e-19 Prostate cancer (SNP x SNP interaction); LIHC cis rs2067615 0.579 rs11113119 chr12:107200056 C/A cg15890332 chr12:107067104 RFX4 0.26 6.2 0.32 1.59e-9 Heart rate; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg00249093 chr19:5804642 NA 0.46 6.14 0.32 2.33e-9 Hepatitis; LIHC trans rs3749237 0.964 rs7431078 chr3:49808190 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.65 10.18 0.48 1.89e-21 Resting heart rate; LIHC cis rs16854884 0.657 rs35309714 chr3:143735011 T/A cg06585982 chr3:143692056 C3orf58 0.54 7.06 0.36 9.48e-12 Economic and political preferences (feminism/equality); LIHC cis rs11671005 0.735 rs56290606 chr19:58919320 A/G cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs7617480 0.616 rs9873227 chr3:48773108 G/C cg07636037 chr3:49044803 WDR6 0.76 9.01 0.44 1.49e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9902453 0.817 rs2321333 chr17:28140857 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 13.71 0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs6430585 0.528 rs309151 chr2:136661150 C/T cg07169764 chr2:136633963 MCM6 1.28 21.37 0.76 5.78e-65 Corneal structure; LIHC cis rs546131 0.890 rs485845 chr11:34830389 G/T cg11058730 chr11:34937778 PDHX;APIP -0.62 -9.34 -0.45 1.23e-18 Lung disease severity in cystic fibrosis; LIHC trans rs7618501 1.000 rs9855505 chr3:49792158 T/G cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.63 -0.34 1.3100000000000001e-10 Intelligence (multi-trait analysis); LIHC cis rs700651 0.789 rs5007118 chr2:198909738 G/C cg10820045 chr2:198174542 NA 0.44 6.48 0.33 3.18e-10 Intracranial aneurysm; LIHC cis rs908922 0.676 rs1572533 chr1:152509742 T/C cg20991723 chr1:152506922 NA 0.55 9.53 0.46 3.1e-19 Hair morphology; LIHC cis rs2055729 0.507 rs814424 chr8:9942924 C/T cg21625330 chr8:9911636 MSRA 0.55 7.28 0.37 2.27e-12 Multiple myeloma (hyperdiploidy); LIHC cis rs74417235 0.684 rs13179754 chr5:154059845 C/T cg19735590 chr5:154026979 NA 0.47 5.9 0.3 8.66e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs3806843 0.966 rs2563262 chr5:140137712 C/G cg19875535 chr5:140030758 IK -0.36 -5.78 -0.3 1.7e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7044106 0.648 rs2031369 chr9:123360294 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.78 0.39 8.75e-14 Hip circumference adjusted for BMI; LIHC cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.22e-8 Menopause (age at onset); LIHC cis rs11190604 0.767 rs872290 chr10:102198879 G/A cg07080220 chr10:102295463 HIF1AN 0.48 6.91 0.35 2.42e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs35110281 0.774 rs141521 chr21:44963686 G/A cg21573476 chr21:45109991 RRP1B -0.53 -9.78 -0.47 4.49e-20 Mean corpuscular volume; LIHC cis rs992157 0.798 rs1017698 chr2:219170525 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.78 -12.83 -0.57 4.85e-31 Colorectal cancer; LIHC cis rs7659604 0.540 rs4075065 chr4:122683906 A/G cg19671926 chr4:122722719 EXOSC9 0.51 7.89 0.39 3.99e-14 Type 2 diabetes; LIHC cis rs920590 0.721 rs920587 chr8:19663339 C/A cg17834443 chr8:19674713 INTS10 0.49 7.4 0.37 1.06e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00049502 chr12:112280971 C12orf47;MAPKAPK5 0.38 6.16 0.32 2.05e-9 Cognitive function; LIHC cis rs2070488 0.775 rs7649984 chr3:38570221 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.58 -9.04 -0.44 1.21e-17 Electrocardiographic conduction measures; LIHC cis rs904251 0.523 rs9369005 chr6:37483109 A/G cg01843034 chr6:37503916 NA -0.46 -7.98 -0.4 2.17e-14 Cognitive performance; LIHC cis rs10504229 0.636 rs72649123 chr8:58045789 A/T cg20607798 chr8:58055168 NA 0.47 6.42 0.33 4.58e-10 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.15 0.55 1.79e-28 Prudent dietary pattern; LIHC cis rs7937682 0.889 rs493810 chr11:111491888 G/T cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs1843834 0.858 rs4674933 chr2:225514923 C/T cg12698349 chr2:225449008 CUL3 0.44 5.77 0.3 1.73e-8 IgE levels in asthmatics (D.p. specific); LIHC cis rs7617773 0.780 rs34946886 chr3:48338487 A/G cg11946769 chr3:48343235 NME6 0.92 11.62 0.53 1.58e-26 Coronary artery disease; LIHC cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg07424592 chr7:64974309 NA 0.8 9.43 0.45 6.25e-19 Diabetic kidney disease; LIHC cis rs6752107 0.936 rs10178603 chr2:234206610 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.51 7.45 0.37 7.77e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs6960043 0.782 rs4721401 chr7:15064896 T/G cg19272540 chr7:15055459 NA -0.24 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC trans rs3820928 0.605 rs4675124 chr2:227802354 G/A cg16088116 chr21:44841560 SIK1 -0.4 -6.1 -0.31 2.83e-9 Pulmonary function; LIHC cis rs4604732 0.536 rs61184655 chr1:247651342 T/C cg02104434 chr1:247694406 LOC148824;OR2C3 0.25 6.02 0.31 4.56e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg03806693 chr22:41940476 POLR3H -1.0 -11.51 -0.53 3.93e-26 Vitiligo; LIHC trans rs792448 0.743 rs2516331 chr1:212416989 C/A cg20223728 chr6:6006398 NRN1 0.35 6.12 0.31 2.51e-9 White blood cell count (basophil); LIHC cis rs9814567 1.000 rs2056604 chr3:134312648 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11190604 1.000 rs7079136 chr10:102292709 T/C cg07080220 chr10:102295463 HIF1AN 0.57 8.09 0.4 1.05e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17756712 0.697 rs2294669 chr6:625673 C/G cg14374089 chr6:596013 EXOC2 0.45 6.49 0.33 2.99e-10 Vertical cup-disc ratio; LIHC cis rs9467773 1.000 rs10484442 chr6:26555879 A/G cg09904177 chr6:26538194 HMGN4 0.65 13.7 0.6 2.39e-34 Intelligence (multi-trait analysis); LIHC cis rs2370759 1.000 rs77165999 chr10:32577131 T/C cg05361325 chr10:32636312 EPC1 -0.52 -6.41 -0.33 4.77e-10 Sexual dysfunction (female); LIHC cis rs9814567 0.762 rs13093893 chr3:134292131 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 7.23 0.36 3.25e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2573652 0.722 rs968412 chr15:100544512 C/G cg09918751 chr15:100517450 ADAMTS17 -0.64 -11.1 -0.51 1.16e-24 Height; LIHC cis rs10857712 0.754 rs1052582 chr10:135233840 C/G cg17796960 chr10:135278976 LOC619207 -0.35 -5.79 -0.3 1.63e-8 Systemic lupus erythematosus; LIHC cis rs344364 0.511 rs1742395 chr16:1955965 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.51 -6.57 -0.33 1.92e-10 Glomerular filtration rate in chronic kidney disease; LIHC trans rs1005277 0.579 rs2474567 chr10:38382492 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs4665809 1.000 rs6546768 chr2:26328800 A/G cg04944784 chr2:26401820 FAM59B -0.65 -8.27 -0.41 3.05e-15 Gut microbiome composition (summer); LIHC cis rs7666738 0.716 rs28792413 chr4:99083707 G/A cg05340658 chr4:99064831 C4orf37 0.69 12.2 0.55 1.15e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs12711979 0.740 rs6711963 chr2:3820915 A/T cg17052675 chr2:3827356 NA -0.42 -7.19 -0.36 4.16e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs1018836 0.884 rs7823461 chr8:91581075 T/C cg16814680 chr8:91681699 NA -0.61 -9.95 -0.47 1.19e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7659604 0.540 rs10024878 chr4:122665451 C/G cg19671926 chr4:122722719 EXOSC9 0.46 6.61 0.34 1.49e-10 Type 2 diabetes; LIHC cis rs1866706 1.000 rs10766000 chr11:12886870 G/C cg25843174 chr11:12811716 TEAD1 0.32 6.5 0.33 2.78e-10 Intelligence (multi-trait analysis); LIHC cis rs4920343 0.698 rs591009 chr1:19086869 A/G cg19637330 chr1:19110922 NA 0.33 6.08 0.31 3.28e-9 Knee osteoarthritis; LIHC cis rs2075371 0.897 rs1643033 chr7:134004662 T/C cg11752832 chr7:134001865 SLC35B4 0.45 6.78 0.34 5.45e-11 Mean platelet volume; LIHC cis rs17826219 0.706 rs2322197 chr17:29105805 T/C cg13385521 chr17:29058706 SUZ12P 0.8 7.98 0.4 2.19e-14 Body mass index; LIHC cis rs1577917 1.000 rs7760207 chr6:86721700 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.94 -0.35 1.97e-11 Response to antipsychotic treatment; LIHC cis rs4819052 0.840 rs914217 chr21:46698299 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 10.09 0.48 3.97e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg22963979 chr7:1858916 MAD1L1 -0.43 -6.94 -0.35 1.99e-11 Bipolar disorder and schizophrenia; LIHC cis rs12472274 0.646 rs34465035 chr2:239114093 C/A cg17459225 chr2:239074497 NA 0.7 10.83 0.51 1.07e-23 Phospholipid levels (plasma); LIHC cis rs6061231 0.675 rs755726 chr20:60962624 T/C cg24112000 chr20:60950667 NA -0.61 -9.77 -0.47 4.91e-20 Colorectal cancer; LIHC cis rs8081395 0.836 rs1292061 chr17:57911230 A/G cg13753209 chr17:57696993 CLTC -0.48 -7.44 -0.37 8.07e-13 White blood cell count; LIHC cis rs57221529 0.825 rs72703051 chr5:582997 G/A cg09021430 chr5:549028 NA -0.44 -7.96 -0.4 2.61e-14 Lung disease severity in cystic fibrosis; LIHC cis rs1707322 0.686 rs2050376 chr1:46078630 C/T cg03146154 chr1:46216737 IPP 0.55 9.01 0.44 1.46e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2839186 0.526 rs59977673 chr21:47922091 C/T cg12379764 chr21:47803548 PCNT -0.53 -7.69 -0.38 1.5700000000000001e-13 Testicular germ cell tumor; LIHC cis rs7223966 1.000 rs72848797 chr17:61934664 G/A cg05941027 chr17:61774174 LIMD2 0.37 7.75 0.39 1.07e-13 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs6934970 1.000 rs6934785 chr6:113124239 C/T cg02462569 chr6:150064036 NUP43 -0.46 -6.09 -0.31 3.1e-9 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg06873352 chr17:61820015 STRADA -0.69 -11.97 -0.54 8.24e-28 Prudent dietary pattern; LIHC trans rs7246657 0.943 rs10415358 chr19:37808863 C/A cg10208301 chr11:6592745 DNHD1 0.47 6.28 0.32 1.01e-9 Coronary artery calcification; LIHC cis rs7408868 1.000 rs7249525 chr19:15277309 G/A cg02272795 chr19:15279244 NOTCH3 -0.31 -5.75 -0.3 2.02e-8 Pulse pressure; LIHC trans rs2262909 0.889 rs61268244 chr19:22310130 C/T cg05197062 chr11:11642011 GALNTL4 0.46 6.75 0.34 6.16e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs7208859 0.673 rs11656845 chr17:29206164 G/T cg14067834 chr17:29058358 SUZ12P 0.66 6.32 0.32 8.02e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs992157 0.932 rs56109829 chr2:219149740 G/A cg00012203 chr2:219082015 ARPC2 0.87 14.16 0.61 3.69e-36 Colorectal cancer; LIHC cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg04944784 chr2:26401820 FAM59B -0.7 -9.19 -0.45 3.86e-18 Gut microbiome composition (summer); LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs950776 0.518 rs62008174 chr15:78808947 C/T cg06917634 chr15:78832804 PSMA4 0.89 12.91 0.57 2.4e-31 Sudden cardiac arrest; LIHC cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2710642 0.525 rs1386401 chr2:62889906 C/G cg17519650 chr2:63277830 OTX1 0.45 7.04 0.36 1.09e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1997103 1.000 rs6957984 chr7:55397331 G/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2153535 0.540 rs9378557 chr6:8517381 T/C cg21535247 chr6:8435926 SLC35B3 0.63 8.29 0.41 2.68e-15 Motion sickness; LIHC cis rs1005277 0.505 rs200937 chr10:38135772 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.6 -0.56 3.56e-30 Extrinsic epigenetic age acceleration; LIHC cis rs3793683 1.000 rs3793683 chr10:134568387 G/T cg06453172 chr10:134556979 INPP5A 0.56 7.83 0.39 6.09e-14 Migraine; LIHC cis rs16828019 0.852 rs71648540 chr1:41722295 G/A cg03387723 chr1:41708464 SCMH1 -0.44 -7.21 -0.36 3.66e-12 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.579 rs2472174 chr10:38375382 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs9733 0.525 rs11584184 chr1:150695689 A/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs9583531 0.527 rs12875067 chr13:111365104 A/G cg15841412 chr13:111365552 ING1 0.47 5.87 0.3 1.04e-8 Coronary artery disease; LIHC cis rs2455799 0.613 rs1976479 chr3:15729714 C/G cg12698662 chr3:15914712 MIR563 -0.37 -6.72 -0.34 7.42e-11 Mean platelet volume; LIHC cis rs6964587 1.000 rs10243241 chr7:91705696 A/G cg17063962 chr7:91808500 NA 1.02 19.58 0.73 8.67e-58 Breast cancer; LIHC trans rs3176789 0.624 rs11052978 chr12:9920478 G/A cg18988856 chr7:99425577 CYP3A43 0.2 6.18 0.32 1.78e-9 Lymphocyte percentage of white cells;Neutrophil percentage of white cells; LIHC cis rs2932538 0.922 rs61818800 chr1:113148571 A/G cg22162597 chr1:113214053 CAPZA1 0.71 10.7 0.5 3.19e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1878931 0.507 rs35214904 chr16:3410017 C/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.69 -8.89 -0.43 3.58e-17 Body mass index (adult); LIHC cis rs17106184 1.000 rs57095912 chr1:51356830 T/G cg07174182 chr1:51127561 FAF1 -0.76 -7.66 -0.38 1.97e-13 Type 2 diabetes; LIHC cis rs2742417 0.603 rs2742395 chr3:45758595 A/G cg04837898 chr3:45731254 SACM1L -0.53 -8.84 -0.43 5.17e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.15e-11 Prudent dietary pattern; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20929545 chr11:118958046 HMBS 0.37 6.23 0.32 1.41e-9 Longevity; LIHC cis rs8180040 0.676 rs7633698 chr3:47013452 A/T cg02527881 chr3:46936655 PTH1R -0.35 -7.16 -0.36 5.02e-12 Colorectal cancer; LIHC cis rs12477438 0.798 rs6542849 chr2:99578493 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.95 -0.47 1.22e-20 Chronic sinus infection; LIHC cis rs1639906 0.893 rs13233298 chr7:2227707 C/T cg04267008 chr7:1944627 MAD1L1 -0.45 -6.26 -0.32 1.13e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs1973993 0.691 rs1980684 chr1:96890636 A/G cg10631902 chr5:14652156 NA 0.36 9.76 0.47 5.13e-20 Weight; LIHC cis rs2816062 0.813 rs2816044 chr1:18892826 A/G cg18795169 chr1:18902165 NA -0.79 -17.43 -0.69 3.77e-49 Urate levels in lean individuals; LIHC cis rs1707322 0.752 rs28890893 chr1:46186576 T/G cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4423214 1.000 rs12790010 chr11:71170653 T/C cg24826892 chr11:71159390 DHCR7 0.48 6.16 0.32 1.99e-9 Vitamin D levels; LIHC cis rs1707322 0.752 rs12047629 chr1:46162802 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs546131 0.928 rs552868 chr11:34830694 G/A cg06937548 chr11:34938143 PDHX;APIP 0.58 7.88 0.39 4.49e-14 Lung disease severity in cystic fibrosis; LIHC cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg16405210 chr4:1374714 KIAA1530 0.69 10.2 0.48 1.72e-21 Obesity-related traits; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg00091569 chr3:40428383 ENTPD3 -0.38 -6.53 -0.33 2.36e-10 Renal cell carcinoma; LIHC cis rs12701220 0.895 rs12534778 chr7:1065861 C/T cg16145915 chr7:1198662 ZFAND2A 0.3 5.75 0.3 2.02e-8 Bronchopulmonary dysplasia; LIHC cis rs1577917 0.771 rs9362232 chr6:86353622 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.63 -0.42 2.4e-16 Response to antipsychotic treatment; LIHC cis rs911119 0.657 rs2145231 chr20:23625547 A/G cg16589663 chr20:23618590 CST3 -0.62 -6.25 -0.32 1.24e-9 Chronic kidney disease; LIHC cis rs9916302 0.851 rs11078904 chr17:37650569 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC cis rs12478296 1.000 rs55767645 chr2:242999350 G/A cg05760424 chr2:242988095 NA -0.54 -7.14 -0.36 5.49e-12 Obesity-related traits; LIHC trans rs911555 0.723 rs2273701 chr14:103923225 G/T cg17675199 chr6:35436792 RPL10A -0.44 -9.21 -0.45 3.25e-18 Intelligence (multi-trait analysis); LIHC cis rs875971 0.545 rs4718348 chr7:65906576 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 6.94 0.35 2e-11 Aortic root size; LIHC cis rs7474896 0.559 rs2738185 chr10:38247736 G/A cg25427524 chr10:38739819 LOC399744 0.45 5.92 0.3 7.74e-9 Obesity (extreme); LIHC cis rs12594515 0.506 rs74199860 chr15:45989190 C/T cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.69e-10 Waist circumference;Weight; LIHC cis rs34540877 0.793 rs36054879 chr19:33150858 T/C cg22980127 chr19:33182716 NUDT19 0.86 5.98 0.31 5.74e-9 Red cell distribution width; LIHC cis rs10540 1.000 rs10540 chr11:494662 G/A cg03352830 chr11:487213 PTDSS2 0.82 6.88 0.35 2.87e-11 Body mass index; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06679563 chr19:33622563 WDR88 0.43 6.97 0.35 1.59e-11 Longevity; LIHC cis rs7296418 0.754 rs1619283 chr12:123717362 A/G cg00376283 chr12:123451042 ABCB9 0.68 11.09 0.51 1.24e-24 Platelet count; LIHC cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs4853012 0.941 rs60291089 chr2:74344890 T/G cg20011983 chr2:74347215 NA -0.39 -5.75 -0.3 2e-8 Gestational age at birth (maternal effect); LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg21448741 chr8:58168803 NA 0.36 6.72 0.34 7.69e-11 Developmental language disorder (linguistic errors); LIHC cis rs2637266 1.000 rs12414151 chr10:78359041 T/G cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.14e-8 Pulmonary function; LIHC trans rs4718428 0.672 rs13241598 chr7:66300652 A/G cg10756647 chr7:56101905 PSPH 0.63 8.6 0.42 2.84e-16 Corneal structure; LIHC cis rs2070433 0.752 rs60290737 chr21:47837630 C/A cg12379764 chr21:47803548 PCNT 0.7 9.85 0.47 2.5e-20 Lymphocyte counts; LIHC cis rs10751667 0.961 rs7943115 chr11:973885 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.45 0.53 6.71e-26 Alzheimer's disease (late onset); LIHC cis rs2991971 0.810 rs12738318 chr1:45929589 A/G cg15605315 chr1:45957053 TESK2 -0.49 -6.75 -0.34 6.51e-11 High light scatter reticulocyte count; LIHC cis rs34779708 0.931 rs68039650 chr10:35385499 C/A cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4906332 0.966 rs2065016 chr14:103879656 T/A cg04998671 chr14:104000505 TRMT61A -0.45 -6.23 -0.32 1.34e-9 Coronary artery disease; LIHC cis rs2242116 0.896 rs724448 chr3:46935734 A/C cg02527881 chr3:46936655 PTH1R -0.54 -11.92 -0.54 1.2e-27 Birth weight; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.28 -0.32 1.01e-9 Total body bone mineral density; LIHC cis rs595982 0.559 rs17206714 chr19:49362001 T/A cg15549821 chr19:49342101 PLEKHA4 -0.7 -6.69 -0.34 8.91e-11 Red cell distribution width; LIHC cis rs6831352 0.918 rs29001211 chr4:100051941 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4919087 1.000 rs7067835 chr10:99074649 T/C cg25902810 chr10:99078978 FRAT1 0.7 10.78 0.5 1.65e-23 Monocyte count; LIHC cis rs7903847 0.642 rs61863819 chr10:99142400 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.57 -0.33 1.83e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10870270 0.500 rs9419217 chr10:133758379 A/G cg17892150 chr10:133769511 PPP2R2D -0.59 -10.42 -0.49 3.02e-22 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7027203 0.790 rs10123836 chr9:96584109 G/T cg14598338 chr9:96623480 NA -0.31 -6.21 -0.32 1.58e-9 DNA methylation (variation); LIHC cis rs904251 0.523 rs2776870 chr6:37481364 C/A cg08126542 chr6:37504118 NA -0.37 -6.3 -0.32 9.03e-10 Cognitive performance; LIHC cis rs1843834 0.823 rs2129610 chr2:225505345 G/A cg22509189 chr2:225307070 NA -0.64 -7.55 -0.38 4.12e-13 IgE levels in asthmatics (D.p. specific); LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12393716 chr11:62495049 TTC9C;HNRNPUL2 0.35 6.1 0.31 2.95e-9 Cognitive function; LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg08280861 chr8:58055591 NA 0.53 6.63 0.34 1.34e-10 Developmental language disorder (linguistic errors); LIHC cis rs7818688 0.546 rs13250762 chr8:95987570 A/G cg16049864 chr8:95962084 TP53INP1 0.52 5.77 0.3 1.81e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1707322 0.821 rs10749857 chr1:46248143 C/T cg03146154 chr1:46216737 IPP 0.51 8.07 0.4 1.19e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs875971 0.706 rs1643374 chr7:65872682 T/A cg26939375 chr7:64535504 NA 0.44 6.72 0.34 7.41e-11 Aortic root size; LIHC cis rs875971 1.000 rs6956179 chr7:65806659 C/T cg18876405 chr7:65276391 NA -0.36 -6.4 -0.33 5.16e-10 Aortic root size; LIHC cis rs6691722 0.503 rs6692646 chr1:24707629 C/T cg18323236 chr1:24743029 NIPAL3 0.41 7.41 0.37 9.79e-13 Response to interferon beta in multiple sclerosis; LIHC cis rs595982 0.527 rs56021835 chr19:49369989 G/A cg21252483 chr19:49399788 TULP2 -0.93 -10.18 -0.48 1.93e-21 Red cell distribution width; LIHC cis rs911119 0.818 rs67862677 chr20:23591086 A/C cg16589663 chr20:23618590 CST3 0.76 7.88 0.39 4.47e-14 Chronic kidney disease; LIHC cis rs116095464 0.558 rs10462755 chr5:246748 T/C cg22857025 chr5:266934 NA -1.47 -17.98 -0.7 2.32e-51 Breast cancer; LIHC cis rs3806843 1.000 rs10073974 chr5:140165231 T/C cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9549367 0.789 rs9577218 chr13:113894911 A/G cg00898013 chr13:113819073 PROZ -0.35 -6.43 -0.33 4.3e-10 Platelet distribution width; LIHC cis rs12477438 0.765 rs62154638 chr2:99639584 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.2 -0.41 4.92e-15 Chronic sinus infection; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg21304211 chr1:112281877 C1orf183 0.42 6.3 0.32 9.25e-10 Migraine with aura; LIHC cis rs36051895 0.659 rs62541540 chr9:5040080 A/G cg02405213 chr9:5042618 JAK2 -0.7 -12.14 -0.55 1.84e-28 Pediatric autoimmune diseases; LIHC cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg10360323 chr17:41437877 NA 0.4 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs2112347 0.502 rs34342 chr5:74934213 A/C cg07671805 chr5:74907694 NA -0.47 -5.8 -0.3 1.49e-8 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC trans rs6866721 0.791 rs7724649 chr5:116216985 T/G cg07571379 chr11:134631427 NA -0.28 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs826838 1.000 rs2129627 chr12:38653036 C/T cg26384229 chr12:38710491 ALG10B 1.08 14.69 0.62 3.18e-38 Heart rate; LIHC cis rs986417 1.000 rs1254323 chr14:60908378 G/A cg27398547 chr14:60952738 C14orf39 -0.82 -9.65 -0.46 1.24e-19 Gut microbiota (bacterial taxa); LIHC trans rs66887589 0.967 rs59516282 chr4:120502016 G/A cg25214090 chr10:38739885 LOC399744 -0.4 -6.53 -0.33 2.38e-10 Diastolic blood pressure; LIHC cis rs7945705 0.870 rs4929922 chr11:8975776 A/G cg12365402 chr11:9010492 NRIP3 -0.31 -8.09 -0.4 1.03e-14 Hemoglobin concentration; LIHC cis rs13191362 0.938 rs35760705 chr6:163020637 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.62 5.9 0.3 8.57e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs73206853 0.764 rs12311093 chr12:110978032 A/G cg12870014 chr12:110450643 ANKRD13A -0.68 -8.31 -0.41 2.23e-15 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs12594515 1.000 rs12592190 chr15:45994028 G/A cg06207120 chr15:45996521 NA 0.32 6.02 0.31 4.55e-9 Waist circumference;Weight; LIHC cis rs4727027 0.933 rs12667123 chr7:148850621 G/A cg23583168 chr7:148888333 NA -0.74 -10.46 -0.49 2.12e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC cis rs9943465 0.688 rs318929 chr10:132071772 T/C cg12765123 chr10:132100019 NA 0.43 6.12 0.31 2.64e-9 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs782590 0.869 rs782599 chr2:55847423 C/T cg03859395 chr2:55845619 SMEK2 0.9 15.68 0.65 3.88e-42 Metabolic syndrome; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg17342834 chr11:535396 HRAS 0.61 7.64 0.38 2.26e-13 Hepatitis; LIHC cis rs919433 0.889 rs788001 chr2:198213720 C/T cg10820045 chr2:198174542 NA 0.53 8.86 0.43 4.41e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2953145 0.568 rs1133354 chr2:241522450 A/G cg07929629 chr2:241523174 NA 0.63 9.32 0.45 1.46e-18 Bipolar disorder; LIHC cis rs8084351 0.599 rs12604508 chr18:50730441 A/G cg24270629 chr18:50823537 DCC -0.45 -6.59 -0.34 1.7e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs10193935 0.748 rs11124879 chr2:42697576 C/A cg27598129 chr2:42591480 NA 0.7 8.93 0.43 2.7e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs12477438 0.501 rs12995473 chr2:99764884 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.55 0.64 1.25e-41 Chronic sinus infection; LIHC cis rs7312933 0.932 rs10880220 chr12:42383046 A/G cg01256987 chr12:42539512 GXYLT1 -0.37 -6.22 -0.32 1.48e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9309711 0.623 rs7569694 chr2:3483390 T/G cg15506890 chr2:3487001 NA -0.47 -7.55 -0.38 3.9e-13 Neurofibrillary tangles; LIHC cis rs6461049 0.800 rs3778977 chr7:2159746 C/T cg20295408 chr7:1910781 MAD1L1 -0.43 -6.34 -0.32 7.15e-10 Schizophrenia; LIHC cis rs244731 0.959 rs7724098 chr5:176659570 G/A cg16006841 chr5:176797999 RGS14 -0.61 -5.97 -0.31 5.9e-9 Urate levels in lean individuals; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27391037 chr22:18560705 PEX26 0.4 6.18 0.32 1.86e-9 Lung function (FEV1/FVC); LIHC cis rs56176327 0.600 rs7628207 chr3:49754970 T/C cg03060546 chr3:49711283 APEH 0.58 6.72 0.34 7.66e-11 Intelligence (multi-trait analysis); LIHC cis rs10857712 0.754 rs2297033 chr10:135234848 C/T cg19623624 chr10:135278901 LOC619207 -0.45 -6.99 -0.35 1.43e-11 Systemic lupus erythematosus; LIHC cis rs1707322 0.721 rs9793568 chr1:46130373 G/A cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4699052 0.963 rs56144793 chr4:104150653 A/G cg16532752 chr4:104119610 CENPE -0.41 -6.62 -0.34 1.43e-10 Testicular germ cell tumor; LIHC cis rs35123781 0.696 rs13179952 chr5:139070573 C/G cg10513866 chr5:139070639 NA 0.45 5.83 0.3 1.31e-8 Schizophrenia; LIHC cis rs7208859 0.623 rs73269916 chr17:29096326 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.95 0.35 1.91e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9368481 0.761 rs7775041 chr6:27009512 T/A cg12292205 chr6:26970375 C6orf41 -0.45 -7.69 -0.38 1.56e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs17401966 1.000 rs12734551 chr1:10391536 A/C cg15208524 chr1:10270712 KIF1B 0.46 6.79 0.34 5.07e-11 Hepatocellular carcinoma; LIHC cis rs4908768 0.501 rs6577502 chr1:8615577 T/C cg20416874 chr1:8611966 RERE -0.7 -15.26 -0.64 1.9e-40 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13430225 chr1:53662423 CPT2 0.49 6.25 0.32 1.21e-9 Hepatitis; LIHC cis rs9640161 0.750 rs3735169 chr7:150034378 A/G cg17279839 chr7:150038598 RARRES2 0.59 11.97 0.54 7.99e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs8017423 0.904 rs4603489 chr14:90760607 A/G cg04374321 chr14:90722782 PSMC1 -0.77 -14.82 -0.63 9.88e-39 Mortality in heart failure; LIHC cis rs9467773 0.967 rs7753565 chr6:26560012 A/G cg09904177 chr6:26538194 HMGN4 0.65 13.64 0.59 3.82e-34 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.967 rs2277517 chr14:90722778 G/A cg14092571 chr14:90743983 NA -0.38 -6.03 -0.31 4.15e-9 Mortality in heart failure; LIHC cis rs35306767 0.903 rs12260800 chr10:927933 T/C cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg26338869 chr17:61819248 STRADA 0.53 7.18 0.36 4.33e-12 Height; LIHC cis rs16854884 0.584 rs59768870 chr3:143738366 G/A cg06585982 chr3:143692056 C3orf58 0.54 6.96 0.35 1.77e-11 Economic and political preferences (feminism/equality); LIHC cis rs7106204 1.000 rs12798139 chr11:24220907 A/G ch.11.24196551F chr11:24239977 NA 0.69 6.98 0.35 1.51e-11 Response to Homoharringtonine (cytotoxicity); LIHC cis rs919433 0.617 rs4850807 chr2:198575975 G/A cg03934865 chr2:198174659 NA -0.48 -6.96 -0.35 1.72e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17497049 chr19:56110871 FIZ1;ZNF524 0.46 6.31 0.32 8.42e-10 Lung function (FEV1/FVC); LIHC cis rs365132 0.875 rs353495 chr5:176430723 T/C cg16309518 chr5:176445507 NA -0.53 -9.89 -0.47 1.88e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs4906332 1.000 rs8004780 chr14:103853360 A/C cg04998671 chr14:104000505 TRMT61A -0.41 -5.75 -0.3 1.94e-8 Coronary artery disease; LIHC trans rs1552244 0.572 rs68121641 chr3:10165845 T/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs208520 1.000 rs72882079 chr6:66973878 T/C cg07460842 chr6:66804631 NA 0.69 7.27 0.37 2.52e-12 Exhaled nitric oxide output; LIHC cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.34 0.45 1.31e-18 Bipolar disorder; LIHC cis rs644799 0.710 rs519511 chr11:95538270 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.76 13.11 0.58 4.33e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12478296 0.581 rs4973645 chr2:242993577 T/C cg18898632 chr2:242989856 NA -0.59 -7.88 -0.39 4.46e-14 Obesity-related traits; LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.720 rs162374 chr21:44927089 T/C cg04455712 chr21:45112962 RRP1B -0.47 -7.83 -0.39 6.24e-14 Mean corpuscular volume; LIHC cis rs10779751 1.000 rs1205592 chr1:11305663 C/T cg08854313 chr1:11322531 MTOR 0.83 11.39 0.52 1.07e-25 Body mass index; LIHC trans rs6600671 1.000 rs12047116 chr1:121185770 G/A cg09829573 chr1:144692074 NBPF9 -0.43 -7.83 -0.39 6.27e-14 Hip geometry; LIHC cis rs1997103 1.000 rs2331064 chr7:55408610 C/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7528419 0.895 rs602633 chr1:109821511 T/G cg20569855 chr1:109824440 PSRC1 0.52 6.63 0.34 1.3100000000000001e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs7953508 0.506 rs10777530 chr12:93961110 C/T cg18151635 chr12:93972918 NA -0.5 -8.59 -0.42 3.24e-16 Pubertal anthropometrics; LIHC cis rs11229555 0.574 rs12272096 chr11:58186118 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7587476 0.784 rs17424051 chr2:215688992 G/C cg04530015 chr2:215796436 ABCA12 -0.4 -6.43 -0.33 4.21e-10 Neuroblastoma; LIHC cis rs9457247 0.534 rs9356551 chr6:167400345 T/C cg12798992 chr6:167411361 FGFR1OP -0.5 -8.11 -0.4 9.41e-15 Crohn's disease; LIHC trans rs6897795 1.000 rs6897795 chr5:177606419 G/A cg19598605 chr2:70056955 GMCL1 -0.62 -7.57 -0.38 3.47e-13 Plateletcrit; LIHC cis rs3008870 1.000 rs3008858 chr1:67390416 G/C cg02640540 chr1:67518911 SLC35D1 0.42 5.78 0.3 1.64e-8 Lymphocyte percentage of white cells; LIHC cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg13395646 chr4:1353034 KIAA1530 -0.66 -9.54 -0.46 2.84e-19 Obesity-related traits; LIHC cis rs959260 1.000 rs2385264 chr17:73364992 C/T cg20590849 chr17:73267439 MIF4GD -0.54 -5.83 -0.3 1.25e-8 Systemic lupus erythematosus; LIHC cis rs929354 0.772 rs1182441 chr7:157026650 A/G cg16102536 chr7:156981717 UBE3C -0.35 -5.9 -0.3 8.69e-9 Body mass index; LIHC cis rs28830936 0.510 rs12440605 chr15:42102285 A/G cg17847044 chr15:42102381 MAPKBP1 0.47 11.48 0.53 5.07e-26 Diastolic blood pressure; LIHC cis rs17213078 0.505 rs6735859 chr2:106744603 T/C cg16099169 chr2:106886729 NA 0.38 5.97 0.31 5.78e-9 Facial morphology (factor 23); LIHC cis rs7659604 0.521 rs6822155 chr4:122673274 C/A cg19671926 chr4:122722719 EXOSC9 0.49 7.25 0.36 2.83e-12 Type 2 diabetes; LIHC cis rs5769765 0.955 rs9616366 chr22:50301178 C/T cg26441486 chr22:50317300 CRELD2 0.35 6.17 0.32 1.88e-9 Schizophrenia; LIHC cis rs910316 0.663 rs175034 chr14:75463687 T/G cg11812906 chr14:75593930 NEK9 -0.74 -13.8 -0.6 1e-34 Height; LIHC cis rs2095921 1 rs2095921 chr1:11033322 C/G cg02454025 chr1:11042201 C1orf127 0.96 18.34 0.7 8.49e-53 Male-pattern baldness; LIHC cis rs7927771 0.965 rs17788930 chr11:47752775 A/G cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.37e-18 Subjective well-being; LIHC cis rs4975616 0.804 rs462608 chr5:1336626 T/A cg06550200 chr5:1325588 CLPTM1L -0.65 -10.38 -0.49 3.9e-22 Lung cancer; LIHC cis rs34172651 0.917 rs6497760 chr16:24806535 G/A cg00152838 chr16:24741724 TNRC6A -0.49 -6.56 -0.33 2.01e-10 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.532 rs2794719 chr6:26088890 T/G cg17691542 chr6:26056736 HIST1H1C 0.4 5.74 0.3 2.07e-8 Height; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg01852063 chr16:1500567 CLCN7 0.34 6.07 0.31 3.49e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg24549020 chr5:56110836 MAP3K1 0.55 7.01 0.35 1.26e-11 Initial pursuit acceleration; LIHC cis rs6907629 0.704 rs879840 chr6:167558739 C/T cg13805183 chr6:167554790 NA -0.26 -6.07 -0.31 3.36e-9 Asthma (childhood onset); LIHC cis rs10504073 0.647 rs62507246 chr8:50013449 G/A cg00325661 chr8:49890786 NA 0.32 7.26 0.37 2.62e-12 Blood metabolite ratios; LIHC cis rs12960505 0.506 rs878571 chr18:50960222 T/C cg24270629 chr18:50823537 DCC -0.49 -6.72 -0.34 7.53e-11 Intelligence (multi-trait analysis); LIHC trans rs56292044 0.706 rs10092669 chr8:138776004 A/G cg05886954 chr16:3631570 BTBD12 0.32 6.13 0.31 2.47e-9 Post bronchodilator FEV1/FVC ratio in COPD; LIHC cis rs4147929 0.532 rs2242437 chr19:1065563 G/C cg05372495 chr19:1063624 ABCA7 -0.42 -6.72 -0.34 7.79e-11 Alzheimer's disease (late onset); LIHC cis rs921968 0.643 rs832799 chr2:219490111 C/A cg18887096 chr2:219472410 PLCD4 0.35 6.06 0.31 3.63e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs9291683 0.588 rs13121211 chr4:9999539 A/G cg11266682 chr4:10021025 SLC2A9 0.29 5.85 0.3 1.12e-8 Bone mineral density; LIHC trans rs561341 0.941 rs4525554 chr17:30312819 T/C cg20587970 chr11:113659929 NA -1.38 -11.71 -0.53 7.6e-27 Hip circumference adjusted for BMI; LIHC cis rs1707322 0.865 rs785501 chr1:46579611 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.75 -0.34 6.35e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9325144 0.555 rs7955128 chr12:38684121 A/T cg26384229 chr12:38710491 ALG10B 0.47 7.22 0.36 3.44e-12 Morning vs. evening chronotype; LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg11766577 chr21:47581405 C21orf56 0.44 7.39 0.37 1.16e-12 Testicular germ cell tumor; LIHC cis rs910316 0.810 rs77939209 chr14:75670070 A/G cg11812906 chr14:75593930 NEK9 -0.65 -11.8 -0.54 3.39e-27 Height; LIHC cis rs853679 0.517 rs7755442 chr6:28039015 T/C cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC trans rs911555 0.755 rs12432803 chr14:103930032 C/T cg17675199 chr6:35436792 RPL10A -0.45 -9.18 -0.44 4.25e-18 Intelligence (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10878170 chr12:12764498 CREBL2 0.37 6.1 0.31 2.82e-9 Calcium levels; LIHC cis rs4975709 0.589 rs1466607 chr5:1864856 A/G cg15595755 chr5:1867978 NA 0.42 8.37 0.41 1.51e-15 Cardiovascular disease risk factors; LIHC cis rs4843747 0.671 rs74729706 chr16:88104159 C/T cg06050784 chr16:88016603 BANP 0.36 6.55 0.33 2.15e-10 Menopause (age at onset); LIHC cis rs5769765 0.773 rs7410304 chr22:50316835 T/C cg26441486 chr22:50317300 CRELD2 0.38 6.45 0.33 3.91e-10 Schizophrenia; LIHC cis rs34779708 0.931 rs34087268 chr10:35346724 T/G cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.4e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9549367 0.737 rs11619691 chr13:113904636 T/C cg18105134 chr13:113819100 PROZ -0.68 -11.64 -0.53 1.29e-26 Platelet distribution width; LIHC cis rs2836950 0.545 rs11700813 chr21:40517469 T/G cg06238570 chr21:40685208 BRWD1 -0.38 -6.17 -0.32 1.89e-9 Menarche (age at onset); LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg21782813 chr7:2030301 MAD1L1 0.42 7.06 0.36 9.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs17152411 0.947 rs733400 chr10:126594340 G/A cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs12477438 0.501 rs7349217 chr2:99815146 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.86 15.35 0.64 8.19e-41 Chronic sinus infection; LIHC cis rs6952808 0.693 rs10950413 chr7:1912988 A/G cg04267008 chr7:1944627 MAD1L1 -0.56 -8.53 -0.42 4.85e-16 Bipolar disorder and schizophrenia; LIHC cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg23978390 chr7:1156363 C7orf50 0.63 9.82 0.47 3.29e-20 Longevity;Endometriosis; LIHC trans rs1814175 0.653 rs10839480 chr11:50034556 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.01 0.35 1.3e-11 Height; LIHC cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg11645453 chr3:52864694 ITIH4 -0.22 -5.73 -0.3 2.2e-8 Bipolar disorder; LIHC cis rs6429082 0.749 rs291362 chr1:235686690 T/A cg26050004 chr1:235667680 B3GALNT2 0.47 7.59 0.38 3.05e-13 Adiposity; LIHC cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.54 0.56 6.33e-30 Total body bone mineral density; LIHC cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg08888203 chr3:10149979 C3orf24 0.53 6.43 0.33 4.35e-10 Alzheimer's disease; LIHC cis rs16828019 0.929 rs1032728 chr1:41679566 A/T cg20697417 chr1:41786797 NA 0.34 6.5 0.33 2.78e-10 Intelligence (multi-trait analysis); LIHC cis rs72634258 0.945 rs4908724 chr1:8119251 G/T cg00042356 chr1:8021962 PARK7 0.9 8.78 0.43 7.76e-17 Inflammatory bowel disease; LIHC cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg01368799 chr11:117014884 PAFAH1B2 0.41 5.81 0.3 1.41e-8 Blood protein levels; LIHC cis rs6001027 0.540 rs1005529 chr22:38541266 T/C cg25457927 chr22:38595422 NA -0.25 -6.15 -0.32 2.22e-9 Melanoma; LIHC cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC trans rs877282 0.898 rs12357995 chr10:765739 T/C cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs4566357 0.539 rs10933164 chr2:227860671 A/G cg05526886 chr2:227700861 RHBDD1 -0.55 -5.97 -0.31 6.01e-9 Coronary artery disease; LIHC cis rs6754311 0.550 rs3213889 chr2:136511575 A/G cg15123519 chr2:136567270 LCT 0.44 8.85 0.43 4.86e-17 Mosquito bite size; LIHC cis rs826838 1.000 rs11168218 chr12:38884466 A/G cg13010199 chr12:38710504 ALG10B 0.61 7.49 0.38 6.09e-13 Heart rate; LIHC cis rs6088580 0.634 rs4142007 chr20:32990050 G/T cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs854572 0.600 rs705382 chr7:94955221 C/G cg04155289 chr7:94953770 PON1 -0.39 -6.49 -0.33 2.95e-10 Paraoxonase activity; LIHC cis rs9916302 0.784 rs4795361 chr17:37573446 G/A cg00129232 chr17:37814104 STARD3 -0.41 -6.5 -0.33 2.9e-10 Glomerular filtration rate (creatinine); LIHC cis rs9534288 0.619 rs6561292 chr13:46683560 G/T cg15192986 chr13:46630673 CPB2 0.49 6.81 0.35 4.39e-11 Blood protein levels; LIHC cis rs4934494 0.681 rs3740035 chr10:91476465 T/C cg19698084 chr10:91461284 KIF20B -0.47 -6.35 -0.32 6.84e-10 Red blood cell count; LIHC cis rs2842992 0.872 rs2758315 chr6:160158640 T/C cg26839252 chr6:160211577 TCP1;MRPL18 0.33 5.72 0.3 2.38e-8 Age-related macular degeneration (geographic atrophy); LIHC cis rs6500602 0.647 rs4786519 chr16:4584406 C/T cg08645402 chr16:4508243 NA 0.41 7.37 0.37 1.31e-12 Schizophrenia; LIHC cis rs7945718 0.535 rs7114698 chr11:12707876 C/T cg25843174 chr11:12811716 TEAD1 0.34 7.75 0.39 1.09e-13 Educational attainment (years of education); LIHC cis rs7918232 0.882 rs788211 chr10:27479070 C/T cg14240646 chr10:27532245 ACBD5 0.71 6.85 0.35 3.54e-11 Breast cancer; LIHC cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.98 -0.31 5.68e-9 Colorectal cancer; LIHC cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg11987759 chr7:65425863 GUSB -0.39 -6.11 -0.31 2.75e-9 Aortic root size; LIHC cis rs10949834 0.715 rs710968 chr7:73497728 A/G cg07137043 chr7:73588983 EIF4H 0.56 6.19 0.32 1.71e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs9467773 1.000 rs3736781 chr6:26505362 G/A cg09904177 chr6:26538194 HMGN4 0.66 13.77 0.6 1.21e-34 Intelligence (multi-trait analysis); LIHC cis rs787274 0.867 rs787279 chr9:115539514 T/C cg13803584 chr9:115635662 SNX30 -0.56 -6.25 -0.32 1.21e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1862618 0.671 rs252897 chr5:56223000 G/A cg12311346 chr5:56204834 C5orf35 -0.44 -5.94 -0.31 6.84e-9 Initial pursuit acceleration; LIHC cis rs2204008 0.806 rs11525001 chr12:38234397 A/G cg13010199 chr12:38710504 ALG10B 0.48 5.83 0.3 1.25e-8 Bladder cancer; LIHC cis rs400736 0.894 rs226242 chr1:8033468 G/A cg25007680 chr1:8021821 PARK7 0.61 9.83 0.47 2.95e-20 Response to antidepressants and depression; LIHC cis rs1707322 0.963 rs10890373 chr1:46393755 A/C cg03146154 chr1:46216737 IPP 0.46 7.2 0.36 3.96e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18691055 chr10:129924607 MKI67 -0.47 -6.24 -0.32 1.32e-9 Pancreatic cancer; LIHC cis rs2066819 1.000 rs77131854 chr12:56664231 C/T cg26714650 chr12:56694279 CS -1.38 -13.24 -0.58 1.4e-32 Psoriasis vulgaris; LIHC cis rs72781680 1.000 rs12616899 chr2:24165235 A/G cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs965469 1.000 rs2281497 chr20:3258874 G/A cg25506879 chr20:3388711 C20orf194 -0.59 -7.26 -0.37 2.67e-12 IFN-related cytopenia; LIHC cis rs616402 0.527 rs604814 chr1:10567122 G/A cg17425144 chr1:10567563 PEX14 0.63 12.89 0.57 2.92e-31 Breast size; LIHC cis rs7618501 0.501 rs7627864 chr3:49926613 C/G cg24110177 chr3:50126178 RBM5 -0.55 -8.66 -0.42 1.95e-16 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.29e-11 Prudent dietary pattern; LIHC cis rs11676348 0.772 rs12694427 chr2:218945045 C/T cg00012203 chr2:219082015 ARPC2 -0.44 -5.85 -0.3 1.14e-8 Ulcerative colitis; LIHC cis rs9457247 0.846 rs2757052 chr6:167380174 T/C cg12798992 chr6:167411361 FGFR1OP -0.6 -9.85 -0.47 2.62e-20 Crohn's disease; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg23250374 chr4:57253573 AASDH -0.38 -6.05 -0.31 3.77e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs3020736 0.500 rs11090076 chr22:42514190 T/C cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.13 -0.31 2.37e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7100689 0.622 rs7897994 chr10:82133304 T/G cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.24e-12 Post bronchodilator FEV1; LIHC cis rs35883536 0.513 rs4907910 chr1:101013277 T/A cg14515779 chr1:101123966 NA -0.46 -6.61 -0.34 1.46e-10 Monocyte count; LIHC cis rs7726839 0.540 rs72703079 chr5:595173 T/C cg09021430 chr5:549028 NA -0.42 -8.44 -0.42 9.17e-16 Obesity-related traits; LIHC cis rs9378688 0.654 rs2505678 chr6:2344158 A/G cg12303981 chr6:2244766 GMDS -0.45 -6.06 -0.31 3.62e-9 Caudate nucleus volume; LIHC cis rs67460515 0.892 rs35100811 chr3:161084046 A/C cg17135325 chr3:160939158 NMD3 0.52 7.46 0.37 7.39e-13 Parkinson's disease; LIHC cis rs2303759 0.676 rs7248378 chr19:49908144 C/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.7 0.43 1.41e-16 Multiple sclerosis; LIHC cis rs12931792 0.720 rs12102320 chr16:30178516 A/C cg17640201 chr16:30407289 ZNF48 0.47 7.5 0.38 5.49e-13 Tonsillectomy; LIHC cis rs8062405 1.000 rs62036622 chr16:28837203 T/G cg07451762 chr16:28383216 NA 0.35 6.43 0.33 4.19e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8180040 0.966 rs807932 chr3:47354241 C/T cg16586182 chr3:47516702 SCAP -0.54 -9.86 -0.47 2.43e-20 Colorectal cancer; LIHC cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.85 0.3 1.14e-8 Calcium levels; LIHC trans rs4942242 0.602 rs61960076 chr13:44217784 T/C cg19169023 chr15:41853346 TYRO3 -0.54 -7.56 -0.38 3.83e-13 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs11945232 1.000 rs28372775 chr4:88343704 G/A cg23841344 chr4:88312519 HSD17B11 -0.55 -7.15 -0.36 5.13e-12 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.864 rs4955410 chr3:49181218 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 7.98 0.4 2.28e-14 Parkinson's disease; LIHC cis rs16828019 0.929 rs35813191 chr1:41742800 T/C cg03962019 chr1:41807865 NA 0.53 7.6 0.38 2.89e-13 Intelligence (multi-trait analysis); LIHC cis rs7586879 0.593 rs10200566 chr2:25130462 G/T cg17466768 chr2:25194156 DNAJC27 -0.41 -5.98 -0.31 5.74e-9 Body mass index; LIHC cis rs11098499 0.739 rs10013032 chr4:120149419 C/T cg09307838 chr4:120376055 NA -0.5 -7.64 -0.38 2.17e-13 Corneal astigmatism; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.753 rs4728550 chr7:75670988 C/A cg16684958 chr7:75615977 POR -0.51 -8.48 -0.42 6.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3818285 0.679 rs552419 chr10:111630883 G/T cg00817464 chr10:111662876 XPNPEP1 0.64 11.0 0.51 2.59e-24 Superior crus of antihelix expression; LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg11598736 chr3:195384522 SDHAP2 0.73 8.75 0.43 9.84e-17 Lung disease severity in cystic fibrosis; LIHC cis rs2073300 1.000 rs6048826 chr20:23458050 C/A cg12062639 chr20:23401060 NAPB 0.78 9.87 0.47 2.16e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2404602 0.647 rs12905181 chr15:77098431 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.42 -0.45 7.09e-19 Blood metabolite levels; LIHC cis rs1494950 0.661 rs72491263 chr4:15080600 C/T cg12377275 chr4:15005593 CPEB2 -0.88 -7.56 -0.38 3.77e-13 Political ideology; LIHC cis rs7772486 0.764 rs2247211 chr6:146216379 G/A cg23711669 chr6:146136114 FBXO30 0.62 10.8 0.5 1.32e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs12701220 0.817 rs1058729 chr7:1087283 C/T cg16145915 chr7:1198662 ZFAND2A -0.29 -5.86 -0.3 1.09e-8 Bronchopulmonary dysplasia; LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.23 0.36 3.23e-12 Height; LIHC cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 5.97 0.31 5.84e-9 Schizophrenia; LIHC cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg17971929 chr21:40555470 PSMG1 0.86 10.41 0.49 3.1e-22 Cognitive function; LIHC cis rs67478160 0.608 rs11160760 chr14:104248938 G/T cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.64 -0.38 2.19e-13 Schizophrenia; LIHC cis rs4819052 0.851 rs7276103 chr21:46666078 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.49 7.11 0.36 7.01e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg26354017 chr1:205819088 PM20D1 -0.75 -11.12 -0.52 9.65e-25 Menarche (age at onset); LIHC cis rs909341 0.859 rs2297441 chr20:62327582 A/G cg03999872 chr20:62272968 STMN3 -0.44 -6.54 -0.33 2.3e-10 Atopic dermatitis; LIHC cis rs7940866 0.874 rs10791113 chr11:130873165 A/G cg12179176 chr11:130786555 SNX19 0.56 7.87 0.39 4.6e-14 Schizophrenia; LIHC cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.82 0.3 1.33e-8 Calcium levels; LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs72781680 0.950 rs72798404 chr2:24180125 C/T cg08917208 chr2:24149416 ATAD2B 0.96 8.25 0.41 3.52e-15 Lymphocyte counts; LIHC cis rs8141529 0.764 rs5762854 chr22:29246278 T/C cg15103426 chr22:29168792 CCDC117 0.67 11.39 0.52 1.1e-25 Lymphocyte counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02781704 chr3:194033517 NA -0.51 -6.9 -0.35 2.48e-11 Pancreatic cancer; LIHC cis rs9513627 0.920 rs2390280 chr13:100208802 A/G cg25919922 chr13:100150906 NA 0.76 6.67 0.34 1.02e-10 Obesity-related traits; LIHC cis rs903552 0.673 rs4965878 chr15:102009589 C/T cg00659931 chr15:102010125 PCSK6 -0.52 -6.93 -0.35 2.07e-11 Diabetic kidney disease; LIHC cis rs7617773 0.780 rs13066044 chr3:48377276 C/T cg11946769 chr3:48343235 NME6 0.93 11.81 0.54 3.03e-27 Coronary artery disease; LIHC cis rs7756236 0.521 rs9462208 chr6:36627890 T/C cg08179530 chr6:36648295 CDKN1A 0.41 6.07 0.31 3.41e-9 QRS duration; LIHC cis rs600231 0.706 rs10896016 chr11:65335705 C/T cg17120908 chr11:65337727 SSSCA1 0.48 6.97 0.35 1.68e-11 Bone mineral density; LIHC cis rs9733 0.596 rs12085275 chr1:150650265 T/C cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Tonsillectomy; LIHC cis rs12497850 1.000 rs6788650 chr3:48749543 T/C cg06212747 chr3:49208901 KLHDC8B 0.49 6.43 0.33 4.35e-10 Parkinson's disease; LIHC cis rs3790844 0.955 rs3790848 chr1:200006111 C/A cg07208853 chr1:200005219 NR5A2 0.35 7.65 0.38 2.11e-13 Pancreatic cancer; LIHC cis rs7572733 0.514 rs770659 chr2:198669754 G/C cg03934865 chr2:198174659 NA 0.46 6.58 0.34 1.74e-10 Dermatomyositis; LIHC cis rs2370759 1.000 rs7910776 chr10:32639093 C/T cg01819863 chr10:32635814 EPC1 1.04 14.53 0.62 1.36e-37 Sexual dysfunction (female); LIHC cis rs34172651 0.917 rs17771137 chr16:24792242 G/A cg00152838 chr16:24741724 TNRC6A -0.48 -6.43 -0.33 4.41e-10 Intelligence (multi-trait analysis); LIHC cis rs1865721 1.000 rs17283454 chr18:73186619 G/A cg26385618 chr18:73139727 C18orf62 -0.3 -7.75 -0.39 1.07e-13 Intelligence; LIHC cis rs875971 0.862 rs6960446 chr7:65733259 A/G cg11764359 chr7:65958608 NA -0.77 -13.25 -0.58 1.25e-32 Aortic root size; LIHC cis rs6430585 0.527 rs60966546 chr2:136401843 C/T cg07169764 chr2:136633963 MCM6 0.66 8.49 0.42 6.18e-16 Corneal structure; LIHC cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg16145915 chr7:1198662 ZFAND2A -0.36 -9.4 -0.45 7.95e-19 Longevity;Endometriosis; LIHC cis rs9818758 0.505 rs67286839 chr3:49265744 C/T cg07636037 chr3:49044803 WDR6 -0.81 -8.44 -0.42 9.01e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2834188 1.000 rs2026254 chr21:34688032 C/T cg14352951 chr21:34696688 IFNAR1 0.48 6.59 0.34 1.69e-10 Narcolepsy; LIHC cis rs10883723 0.810 rs10883729 chr10:104273943 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.64 0.56 2.67e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2404602 0.655 rs4886824 chr15:76969256 A/G cg03037974 chr15:76606532 NA 0.74 14.52 0.62 1.56e-37 Blood metabolite levels; LIHC trans rs6934970 0.860 rs12213194 chr6:112984943 C/T cg09308777 chr6:169852575 NA 0.59 6.04 0.31 3.93e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6502050 0.835 rs66932937 chr17:80116803 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.68e-9 Life satisfaction; LIHC trans rs116095464 0.558 rs56127718 chr5:270273 G/T cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs1182196 0.533 rs2527521 chr7:2904928 A/G cg13628971 chr7:2884303 GNA12 -0.33 -5.75 -0.3 1.96e-8 Plateletcrit; LIHC cis rs6088590 0.930 rs6087618 chr20:33288407 C/T cg06115741 chr20:33292138 TP53INP2 0.59 8.42 0.41 1.02e-15 Coronary artery disease; LIHC trans rs1814175 0.645 rs599890 chr11:49711718 G/A cg15704280 chr7:45808275 SEPT13 -0.97 -20.44 -0.74 2.93e-61 Height; LIHC trans rs3942852 0.688 rs10742834 chr11:48169717 G/A cg03929089 chr4:120376271 NA -0.56 -7.62 -0.38 2.6e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs5769765 1.000 rs8138941 chr22:50290678 G/A cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.25e-16 Schizophrenia; LIHC cis rs11792861 0.926 rs17729523 chr9:111773317 T/C cg13535736 chr9:111863775 C9orf5 -0.4 -6.11 -0.31 2.7e-9 Menarche (age at onset); LIHC cis rs611744 0.967 rs653081 chr8:109230383 G/T cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs344364 0.511 rs2982446 chr16:1947153 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.4 -0.37 1.05e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs2070433 0.752 rs11700468 chr21:47776391 C/T cg12379764 chr21:47803548 PCNT 0.75 10.44 0.49 2.39e-22 Lymphocyte counts; LIHC cis rs7772486 0.790 rs2253654 chr6:146199445 T/C cg05347473 chr6:146136440 FBXO30 0.39 6.19 0.32 1.72e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11626933 0.959 rs8005973 chr14:90774951 C/T cg14092571 chr14:90743983 NA -0.88 -14.65 -0.62 4.75e-38 Gut microbiota (bacterial taxa); LIHC cis rs6088813 0.857 rs6142378 chr20:33997291 T/A cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC cis rs950776 0.531 rs12915652 chr15:78831928 G/A cg22563815 chr15:78856949 CHRNA5 0.36 6.45 0.33 3.9e-10 Sudden cardiac arrest; LIHC cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg21448741 chr8:58168803 NA 0.38 6.12 0.31 2.54e-9 Developmental language disorder (linguistic errors); LIHC cis rs62458065 1.000 rs6462363 chr7:32464759 T/G cg06627557 chr7:32535165 LSM5;AVL9 -0.64 -7.32 -0.37 1.77e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs9896052 0.591 rs7212620 chr17:73461930 A/T cg25649188 chr17:73499917 CASKIN2 0.4 6.78 0.34 5.43e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs7903847 0.602 rs7916665 chr10:99157573 T/G cg20016023 chr10:99160130 RRP12 -0.43 -6.72 -0.34 7.81e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs2153535 0.580 rs2225765 chr6:8481785 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs713477 1.000 rs8014526 chr14:55885054 C/G cg13175173 chr14:55914753 NA -0.32 -7.13 -0.36 5.98e-12 Pediatric bone mineral content (femoral neck); LIHC trans rs61931739 0.500 rs11053235 chr12:34507899 G/A cg26384229 chr12:38710491 ALG10B 0.79 9.79 0.47 4.2e-20 Morning vs. evening chronotype; LIHC cis rs2932538 0.961 rs4838960 chr1:113163632 G/T cg22162597 chr1:113214053 CAPZA1 -0.68 -10.78 -0.5 1.64e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg25894440 chr7:65020034 NA -0.55 -6.31 -0.32 8.76e-10 Diabetic kidney disease; LIHC cis rs7131987 0.834 rs12228468 chr12:29453610 A/C cg00204748 chr12:29376779 FAR2 -0.34 -6.36 -0.33 6.56e-10 QT interval; LIHC cis rs116095464 0.558 rs73031482 chr5:227594 G/A cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs734999 0.545 rs9970196 chr1:2574078 T/C cg18854424 chr1:2615690 NA -0.33 -7.32 -0.37 1.76e-12 Ulcerative colitis; LIHC cis rs7223966 1.000 rs9912201 chr17:61763208 A/G cg05941027 chr17:61774174 LIMD2 0.34 6.91 0.35 2.32e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9457247 0.508 rs9459874 chr6:167504127 A/G cg12798992 chr6:167411361 FGFR1OP -0.35 -5.72 -0.3 2.29e-8 Crohn's disease; LIHC cis rs7552404 1.000 rs11161510 chr1:76210289 A/G cg03433033 chr1:76189801 ACADM -0.66 -9.28 -0.45 2.04e-18 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs11039798 0.588 rs61932767 chr11:48704806 C/T cg03929089 chr4:120376271 NA 0.53 6.04 0.31 4.13e-9 Axial length; LIHC cis rs1823913 0.895 rs10931491 chr2:192120813 G/A cg12404831 chr2:192114017 MYO1B -0.33 -6.5 -0.33 2.9e-10 Obesity-related traits; LIHC cis rs66887589 0.934 rs12648182 chr4:120503891 T/A cg09307838 chr4:120376055 NA -0.49 -7.43 -0.37 8.72e-13 Diastolic blood pressure; LIHC cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.27e-19 Initial pursuit acceleration; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.54 -7.64 -0.38 2.17e-13 Lymphocyte counts; LIHC cis rs12744310 1.000 rs36143444 chr1:41764310 C/T cg03962019 chr1:41807865 NA 0.39 6.28 0.32 1.06e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25936770 chr7:122321411 CADPS2 0.41 6.35 0.32 6.84e-10 Immature fraction of reticulocytes; LIHC cis rs7772486 0.714 rs1883365 chr6:146076749 C/T cg23711669 chr6:146136114 FBXO30 -0.64 -11.56 -0.53 2.65e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9733 0.596 rs2867304 chr1:150630995 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC trans rs7395662 0.553 rs4882155 chr11:48705801 T/C cg15704280 chr7:45808275 SEPT13 -0.51 -7.69 -0.38 1.55e-13 HDL cholesterol; LIHC cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg04267008 chr7:1944627 MAD1L1 -0.63 -10.28 -0.49 8.71e-22 Bipolar disorder and schizophrenia; LIHC cis rs9911578 0.839 rs7208505 chr17:57187729 C/T cg12560992 chr17:57184187 TRIM37 0.92 15.88 0.65 6.15e-43 Intelligence (multi-trait analysis); LIHC cis rs4979906 1.000 rs11002244 chr10:79446207 T/C cg07817648 chr10:79422355 NA -0.3 -6.1 -0.31 2.86e-9 Mortality in heart failure; LIHC cis rs7296418 0.580 rs78455769 chr12:123856443 G/A cg00376283 chr12:123451042 ABCB9 0.62 10.35 0.49 5.15e-22 Platelet count; LIHC cis rs67257959 0.708 rs13343952 chr19:17197064 G/C cg16202187 chr19:17186497 HAUS8;MYO9B 0.36 5.8 0.3 1.5e-8 Selective IgA deficiency; LIHC cis rs798554 0.567 rs1182191 chr7:2869364 A/T cg19717773 chr7:2847554 GNA12 -0.43 -7.24 -0.36 2.9e-12 Height; LIHC cis rs2295359 0.892 rs10889657 chr1:67615487 A/G cg12940439 chr1:67600707 NA 0.39 6.96 0.35 1.71e-11 Psoriasis; LIHC cis rs208520 1.000 rs12193077 chr6:66989548 C/T cg07460842 chr6:66804631 NA 0.67 7.29 0.37 2.24e-12 Exhaled nitric oxide output; LIHC cis rs965469 0.779 rs6133034 chr20:3337661 A/G cg25506879 chr20:3388711 C20orf194 -0.51 -6.24 -0.32 1.27e-9 IFN-related cytopenia; LIHC cis rs780096 0.546 rs8179225 chr2:27737181 A/G cg27432699 chr2:27873401 GPN1 -0.6 -8.59 -0.42 3.11e-16 Total body bone mineral density; LIHC cis rs74417235 0.684 rs7723312 chr5:154053249 A/G cg08754654 chr5:154026448 NA -0.32 -7.18 -0.36 4.51e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs11148252 0.574 rs9536247 chr13:53279542 T/C cg00495681 chr13:53174319 NA 0.7 12.6 0.56 3.78e-30 Lewy body disease; LIHC cis rs798554 0.757 rs1182181 chr7:2873247 C/G cg19346786 chr7:2764209 NA -0.43 -6.11 -0.31 2.66e-9 Height; LIHC cis rs727505 1.000 rs720613 chr7:124452670 C/T cg23710748 chr7:124431027 NA -0.33 -5.92 -0.3 8.01e-9 Lewy body disease; LIHC cis rs116095464 0.614 rs10061564 chr5:271329 T/C cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs7098414 0.511 rs10749592 chr10:82150891 C/T cg00277334 chr10:82204260 NA -0.6 -9.84 -0.47 2.81e-20 Post bronchodilator FEV1; LIHC cis rs11122272 0.735 rs2572248 chr1:231514942 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg10755058 chr3:40428713 ENTPD3 -0.35 -5.97 -0.31 6.06e-9 Renal cell carcinoma; LIHC trans rs11098499 0.863 rs13134665 chr4:120426430 T/C cg25214090 chr10:38739885 LOC399744 0.59 9.47 0.46 4.91e-19 Corneal astigmatism; LIHC cis rs904251 0.861 rs1757173 chr6:37486952 A/C cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.39e-12 Cognitive performance; LIHC cis rs12540874 0.698 rs13234331 chr7:50560314 G/T cg18232548 chr7:50535776 DDC -0.42 -6.3 -0.32 9.11e-10 Systemic sclerosis; LIHC cis rs9309473 0.950 rs13427832 chr2:73844818 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.84 -0.35 3.61e-11 Metabolite levels; LIHC cis rs644799 0.562 rs515546 chr11:95588756 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.59 8.49 0.42 6.55e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs17685 0.672 rs10952841 chr7:75778626 A/C cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4819052 0.851 rs28676615 chr21:46676576 G/C cg22633049 chr21:46681294 NA -0.36 -6.13 -0.31 2.47e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12048904 0.619 rs12239082 chr1:101330077 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.73 -11.82 -0.54 2.88e-27 Multiple sclerosis; LIHC cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg21782813 chr7:2030301 MAD1L1 0.41 6.93 0.35 2.16e-11 Bipolar disorder and schizophrenia; LIHC cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg08499158 chr17:42289980 UBTF 0.48 7.95 0.4 2.66e-14 Total body bone mineral density; LIHC cis rs9790314 0.747 rs9820825 chr3:160848155 A/G cg03342759 chr3:160939853 NMD3 -0.71 -9.68 -0.46 9.29e-20 Morning vs. evening chronotype; LIHC cis rs870825 0.860 rs2705886 chr4:185608591 T/C cg04058563 chr4:185651563 MLF1IP -0.76 -6.69 -0.34 9.24e-11 Blood protein levels; LIHC cis rs72781680 0.678 rs56145919 chr2:24088489 A/G cg08917208 chr2:24149416 ATAD2B 0.65 6.61 0.34 1.45e-10 Lymphocyte counts; LIHC trans rs11614333 0.523 rs2098434 chr12:15004540 G/T cg08449838 chr12:32112341 C12orf35 0.48 6.34 0.32 7.28e-10 Hand grip strength; LIHC cis rs17125944 0.615 rs17125798 chr14:53319905 G/A cg00686598 chr14:53173677 PSMC6 0.89 9.97 0.47 1.02e-20 Alzheimer's disease (late onset); LIHC cis rs6430585 0.583 rs59243420 chr2:136584538 A/T cg07169764 chr2:136633963 MCM6 1.34 20.93 0.75 3.29e-63 Corneal structure; LIHC cis rs11190604 1.000 rs11190541 chr10:102203071 A/G cg07080220 chr10:102295463 HIF1AN 0.48 6.82 0.35 4.11e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg18252515 chr7:66147081 NA -1.26 -16.63 -0.67 6.04e-46 Diabetic kidney disease; LIHC cis rs12701220 0.947 rs1007765 chr7:1032805 G/C cg26769984 chr7:1090371 C7orf50 0.62 7.63 0.38 2.35e-13 Bronchopulmonary dysplasia; LIHC cis rs7772486 0.790 rs7753092 chr6:146248863 C/T cg13319975 chr6:146136371 FBXO30 0.39 6.23 0.32 1.4e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8014204 1.000 rs10483863 chr14:75322327 A/G cg08847533 chr14:75593920 NEK9 -0.34 -5.72 -0.3 2.31e-8 Caffeine consumption; LIHC cis rs2857078 0.720 rs9901595 chr17:42305699 G/A cg09913183 chr17:42254507 C17orf65;ASB16 0.65 9.61 0.46 1.59e-19 Red cell distribution width;Reticulocyte count; LIHC cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs10256972 0.967 rs4723338 chr7:1036241 A/G cg23978390 chr7:1156363 C7orf50 0.53 8.14 0.4 7.55e-15 Longevity;Endometriosis; LIHC cis rs3736485 0.966 rs12592889 chr15:51795172 G/A cg08986416 chr15:51914746 DMXL2 -0.4 -6.1 -0.31 2.91e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs710865 0.527 rs2275403 chr1:19557713 C/G cg13387374 chr1:19411106 UBR4 -0.55 -8.86 -0.43 4.34e-17 Brain structure; LIHC cis rs11718455 0.920 rs4682927 chr3:44033299 C/A cg08738300 chr3:44038990 NA 0.51 8.95 0.44 2.27e-17 Coronary artery disease; LIHC cis rs6942756 1.000 rs2103232 chr7:128951232 G/T cg02491457 chr7:128862824 NA -0.65 -9.39 -0.45 8.8e-19 White matter hyperintensity burden; LIHC cis rs34779708 0.931 rs35997236 chr10:35376690 C/T cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs13118159 0.801 rs7664474 chr4:1329116 T/A cg02969873 chr4:1330999 MAEA -0.41 -6.22 -0.32 1.47e-9 Longevity; LIHC cis rs7613875 0.620 rs17657664 chr3:50032008 T/G cg21467203 chr3:49911342 NA -0.53 -9.65 -0.46 1.16e-19 Body mass index; LIHC cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg19318889 chr4:1322082 MAEA 0.44 7.22 0.36 3.37e-12 Obesity-related traits; LIHC trans rs2243480 1.000 rs1638734 chr7:66097539 A/C cg10756647 chr7:56101905 PSPH 1.01 11.9 0.54 1.53e-27 Diabetic kidney disease; LIHC cis rs240764 0.658 rs1039030 chr6:101198707 G/A cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.34e-9 Neuroticism; LIHC cis rs7264396 0.616 rs6060744 chr20:34581555 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.49 -8.59 -0.42 3.24e-16 Total cholesterol levels; LIHC cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg20607798 chr8:58055168 NA 0.73 8.06 0.4 1.25e-14 Developmental language disorder (linguistic errors); LIHC cis rs1348850 0.872 rs10165785 chr2:178293295 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.84 13.19 0.58 2.12e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.71 0.38 1.35e-13 Prudent dietary pattern; LIHC cis rs6089584 1.000 rs6142910 chr20:60562181 C/A cg13770153 chr20:60521292 NA -0.35 -6.9 -0.35 2.53e-11 Body mass index; LIHC cis rs17666538 0.535 rs1669658 chr8:607380 A/G cg02524346 chr8:600233 NA 0.87 6.61 0.34 1.51e-10 IgG glycosylation; LIHC trans rs9354352 0.935 rs9354354 chr6:66699333 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.57 -9.16 -0.44 4.94e-18 Initial pursuit acceleration in psychotic disorders; LIHC cis rs2976388 0.609 rs2244152 chr8:143784885 C/A cg06565975 chr8:143823917 SLURP1 0.34 6.59 0.34 1.66e-10 Urinary tract infection frequency; LIHC cis rs7659604 0.540 rs11098643 chr4:122701507 C/A cg19671926 chr4:122722719 EXOSC9 0.54 8.48 0.42 6.86e-16 Type 2 diabetes; LIHC cis rs7903847 0.642 rs12359257 chr10:99136359 A/T cg08345082 chr10:99160200 RRP12 -0.36 -6.01 -0.31 4.74e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg10360323 chr17:41437877 NA 0.4 5.95 0.31 6.7e-9 Menopause (age at onset); LIHC cis rs2228479 0.702 rs62053701 chr16:89860584 G/A cg04013166 chr16:89971882 TCF25 0.49 5.91 0.3 8.48e-9 Skin colour saturation; LIHC trans rs7618501 1.000 rs2271960 chr3:49878078 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.75 13.56 0.59 7.98e-34 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08140343 chr19:37569236 ZNF420 -0.45 -6.45 -0.33 3.91e-10 Pancreatic cancer; LIHC cis rs11190604 1.000 rs11190578 chr10:102238953 C/T cg07080220 chr10:102295463 HIF1AN 0.5 7.09 0.36 7.71e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs2243480 0.803 rs13224048 chr7:65993766 G/A cg10756647 chr7:56101905 PSPH 1.02 12.09 0.55 2.84e-28 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg02290350 chr8:58132656 NA 0.51 11.04 0.51 1.9e-24 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.817 rs1058729 chr7:1087283 C/T cg26769984 chr7:1090371 C7orf50 0.56 7.36 0.37 1.38e-12 Bronchopulmonary dysplasia; LIHC cis rs77637988 0.533 rs13398791 chr2:48622320 G/C cg15846641 chr2:48541264 FOXN2 0.54 7.19 0.36 4.12e-12 Joint mobility (Beighton score); LIHC cis rs11671005 0.735 rs35652377 chr19:58929200 A/C cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs1008375 1.000 rs11722037 chr4:17683811 G/A cg02297831 chr4:17616191 MED28 0.4 6.47 0.33 3.32e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7568498 0.564 rs9287807 chr2:161915361 T/C cg16506815 chr2:162101123 NA -0.41 -6.25 -0.32 1.21e-9 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC trans rs61931739 0.517 rs4931748 chr12:34140827 C/T cg26384229 chr12:38710491 ALG10B 0.51 6.97 0.35 1.61e-11 Morning vs. evening chronotype; LIHC cis rs1580019 0.523 rs13236410 chr7:32690663 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.61 8.83 0.43 5.64e-17 Cognitive ability; LIHC cis rs6782228 0.606 rs2811489 chr3:128337371 A/G cg16766828 chr3:128327626 NA 0.41 6.46 0.33 3.69e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs826838 0.874 rs10880943 chr12:38734317 C/T cg26384229 chr12:38710491 ALG10B 1.07 14.92 0.63 3.91e-39 Heart rate; LIHC cis rs9918079 0.560 rs4698402 chr4:15629803 G/A cg16509355 chr4:15471240 CC2D2A -0.44 -6.74 -0.34 6.83e-11 Obesity-related traits; LIHC cis rs2304069 0.817 rs216132 chr5:149431259 C/T cg12661370 chr5:149340060 SLC26A2 -0.52 -6.38 -0.33 5.66e-10 HIV-1 control; LIHC cis rs6951245 0.938 rs11764937 chr7:1092074 C/T cg08132940 chr7:1081526 C7orf50 -0.84 -7.0 -0.35 1.4e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.65 0.38 2.03e-13 Height; LIHC cis rs1577917 0.958 rs12203457 chr6:86689277 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.31 -0.32 8.59e-10 Response to antipsychotic treatment; LIHC cis rs7474896 0.559 rs1024202 chr10:38278977 A/C cg25427524 chr10:38739819 LOC399744 0.45 6.0 0.31 4.93e-9 Obesity (extreme); LIHC cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg09913183 chr17:42254507 C17orf65;ASB16 -0.63 -9.72 -0.47 6.82e-20 Total body bone mineral density; LIHC cis rs477692 0.699 rs471357 chr10:131389373 C/G cg19680672 chr10:131412579 MGMT -0.4 -6.09 -0.31 2.99e-9 Response to temozolomide; LIHC cis rs1400745 0.756 rs3783316 chr14:35337192 A/G cg16230307 chr14:35515116 FAM177A1 0.38 6.2 0.32 1.64e-9 Monocyte count; LIHC cis rs1568889 1.000 rs7945367 chr11:28166272 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.12 0.36 6.37e-12 Bipolar disorder; LIHC cis rs7772486 0.597 rs6912351 chr6:146264071 T/C cg05347473 chr6:146136440 FBXO30 -0.48 -6.87 -0.35 3.06e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11671005 0.735 rs45617039 chr19:58951096 G/A cg25952890 chr19:58913133 NA 0.71 7.81 0.39 7.16e-14 Mean platelet volume; LIHC trans rs4596713 0.538 rs11145460 chr9:71766091 T/G cg16512924 chr15:28394682 HERC2 0.4 6.41 0.33 4.8e-10 Headache; LIHC cis rs921968 0.612 rs2384950 chr2:219499719 T/C cg18887096 chr2:219472410 PLCD4 0.35 6.01 0.31 4.75e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs12908161 0.920 rs12904605 chr15:85201419 T/C cg17507749 chr15:85114479 UBE2QP1 0.69 7.86 0.39 5.1e-14 Schizophrenia; LIHC cis rs763121 0.925 rs5750654 chr22:39051428 T/C cg14440974 chr22:39074834 NA -0.34 -5.79 -0.3 1.63e-8 Menopause (age at onset); LIHC cis rs899997 1.000 rs12899940 chr15:79001699 A/G cg04896959 chr15:78267971 NA -0.39 -7.76 -0.39 1e-13 Coronary artery disease or large artery stroke; LIHC cis rs10078 0.515 rs2672739 chr5:443447 A/C cg08916839 chr5:415575 AHRR 0.62 12.86 0.57 3.81e-31 Fat distribution (HIV); LIHC cis rs2304069 1.000 rs10072275 chr5:149401596 T/C cg22760475 chr5:149380129 HMGXB3;TIGD6 0.95 12.51 0.56 7.7e-30 HIV-1 control; LIHC cis rs1707322 0.682 rs3014241 chr1:46087879 A/G cg24296786 chr1:45957014 TESK2 0.4 5.72 0.3 2.35e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1080261 0.504 rs6928183 chr6:110799201 A/G cg22334665 chr6:110797497 SLC22A16 0.45 5.76 0.3 1.87e-8 Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid); LIHC cis rs12995491 0.731 rs17435433 chr2:88509616 A/G cg04511125 chr2:88470314 THNSL2 -0.47 -6.81 -0.35 4.5e-11 Response to metformin (IC50); LIHC cis rs55665837 1.000 rs10047457 chr11:14439459 T/A cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19098793 chr7:1609793 KIAA1908;PSMG3 -0.46 -6.1 -0.31 2.87e-9 Pancreatic cancer; LIHC cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg03806693 chr22:41940476 POLR3H 1.11 12.98 0.57 1.32e-31 Vitiligo; LIHC cis rs6584283 0.766 rs7911680 chr10:101293468 A/C cg06854084 chr10:101292507 NKX2-3 -0.32 -5.91 -0.3 8.25e-9 Ulcerative colitis; LIHC cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg06481639 chr22:41940642 POLR3H 0.62 5.86 0.3 1.1e-8 Vitiligo; LIHC cis rs295140 0.546 rs842830 chr2:201131124 C/T cg23649088 chr2:200775458 C2orf69 -0.44 -6.08 -0.31 3.28e-9 QT interval; LIHC cis rs11229555 0.598 rs1893902 chr11:58190747 A/G cg15696309 chr11:58395628 NA -0.65 -7.74 -0.39 1.12e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4629710 0.563 rs9483238 chr6:131567196 A/T cg12606694 chr6:131520996 AKAP7 0.62 7.29 0.37 2.12e-12 Multiple myeloma (IgH translocation); LIHC trans rs16863064 0.660 rs1007308 chr3:187889723 C/T cg02569115 chr17:76922138 TIMP2 0.34 6.09 0.31 3.04e-9 Schizophrenia; LIHC cis rs922107 0.713 rs2061479 chr1:90044165 A/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.73 -0.39 1.24e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs77861329 1.000 rs2304505 chr3:52184760 T/C cg08692210 chr3:52188851 WDR51A 0.84 7.96 0.4 2.65e-14 Macrophage inflammatory protein 1b levels; LIHC trans rs2744203 1.000 rs60002471 chr6:104640064 C/G cg27088726 chr16:83171155 CDH13 -0.46 -6.08 -0.31 3.14e-9 IgG glycosylation; LIHC cis rs17685 0.725 rs2302436 chr7:75676988 A/T cg01364799 chr7:75623366 TMEM120A 0.51 7.54 0.38 4.14e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12701220 0.655 rs6463317 chr7:1159243 G/A cg16145915 chr7:1198662 ZFAND2A -0.32 -6.44 -0.33 4.16e-10 Bronchopulmonary dysplasia; LIHC cis rs68170813 0.559 rs12536485 chr7:106978005 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.86 -0.3 1.08e-8 Coronary artery disease; LIHC cis rs2842992 0.830 rs1853259 chr6:160147441 A/G cg16489826 chr6:160211363 TCP1;MRPL18 -0.54 -9.54 -0.46 2.71e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs4700695 0.668 rs253214 chr5:65499401 A/G cg21114390 chr5:65439923 SFRS12 -0.55 -7.8 -0.39 7.4e-14 Facial morphology (factor 19); LIHC cis rs5769765 0.773 rs7290751 chr22:50318312 T/C cg26441486 chr22:50317300 CRELD2 0.39 6.59 0.34 1.65e-10 Schizophrenia; LIHC cis rs921968 0.643 rs545779 chr2:219336108 A/G cg17980119 chr2:219472607 PLCD4 0.35 6.11 0.31 2.76e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7918232 0.782 rs7910168 chr10:27465296 G/A cg14240646 chr10:27532245 ACBD5 -0.66 -6.29 -0.32 9.9e-10 Breast cancer; LIHC cis rs2576037 0.526 rs2051292 chr18:44484372 C/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.53 -7.84 -0.39 5.62e-14 Personality dimensions; LIHC cis rs4319547 0.876 rs10846978 chr12:122964708 T/C cg23029597 chr12:123009494 RSRC2 -0.54 -7.7 -0.38 1.5e-13 Body mass index; LIHC cis rs10097731 0.901 rs28505206 chr8:82044410 A/G cg25230327 chr8:82042993 NA -0.6 -8.14 -0.4 7.31e-15 Serum total protein level; LIHC cis rs9902453 0.904 rs12951836 chr17:28410277 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -13.25 -0.58 1.21e-32 Coffee consumption (cups per day); LIHC cis rs17685 0.664 rs9801113 chr7:75792031 C/T cg16684958 chr7:75615977 POR 0.52 8.59 0.42 3.22e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs904251 0.504 rs2797795 chr6:37480683 T/C cg25019722 chr6:37503610 NA -0.32 -5.76 -0.3 1.87e-8 Cognitive performance; LIHC cis rs3806843 0.900 rs116210441 chr5:140128649 T/A cg26395211 chr5:140044315 WDR55 0.39 5.84 0.3 1.19e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7520050 0.966 rs10890352 chr1:46283628 G/A cg03146154 chr1:46216737 IPP -0.4 -6.55 -0.33 2.11e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg07424592 chr7:64974309 NA -0.81 -9.63 -0.46 1.45e-19 Diabetic kidney disease; LIHC trans rs4650994 0.507 rs12405456 chr1:178512331 T/G cg05059571 chr16:84539110 KIAA1609 -0.45 -7.5 -0.38 5.39e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg12437481 chr16:420112 MRPL28 -0.66 -9.76 -0.47 5.33e-20 Bone mineral density (spine);Bone mineral density; LIHC cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg07308232 chr7:1071921 C7orf50 -0.48 -7.79 -0.39 7.99e-14 Longevity;Endometriosis; LIHC cis rs17125944 0.615 rs12590862 chr14:53297008 A/G cg00686598 chr14:53173677 PSMC6 -0.88 -10.38 -0.49 4.11e-22 Alzheimer's disease (late onset); LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.91 0.57 2.5e-31 Prudent dietary pattern; LIHC cis rs9733 0.570 rs951281 chr1:150691122 A/C cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs738322 0.577 rs6001034 chr22:38558459 A/G cg25457927 chr22:38595422 NA -0.36 -8.66 -0.42 1.9e-16 Cutaneous nevi; LIHC cis rs864643 1.000 rs572971 chr3:39561427 G/T cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs36051895 0.623 rs10283467 chr9:5244356 C/G cg02405213 chr9:5042618 JAK2 0.63 10.18 0.48 1.93e-21 Pediatric autoimmune diseases; LIHC cis rs10870270 0.913 rs115236491 chr10:133766855 T/G cg26149184 chr10:133730230 NA 0.47 7.37 0.37 1.29e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.05 0.8 2.27e-79 Prudent dietary pattern; LIHC cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg12310025 chr6:25882481 NA -0.72 -8.99 -0.44 1.7e-17 Intelligence (multi-trait analysis); LIHC cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg05555928 chr11:63887634 MACROD1 0.56 7.57 0.38 3.5e-13 Mean platelet volume; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg23906291 chr17:37844223 PGAP3;ERBB2 -0.49 -6.82 -0.35 4.11e-11 Alopecia areata; LIHC cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg08888203 chr3:10149979 C3orf24 0.59 6.75 0.34 6.28e-11 Alzheimer's disease; LIHC cis rs7772486 0.846 rs2492856 chr6:146323928 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -6.03 -0.31 4.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836950 0.501 rs1474490 chr21:40716136 C/A cg11890956 chr21:40555474 PSMG1 -0.44 -7.08 -0.36 8.25e-12 Menarche (age at onset); LIHC cis rs2153535 0.580 rs5001322 chr6:8451608 A/G cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC cis rs9814567 0.896 rs7653880 chr3:134345788 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.59 -9.88 -0.47 2.04e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10540 0.841 rs35601764 chr11:532923 A/C cg03576123 chr11:487126 PTDSS2 -1.0 -7.02 -0.35 1.21e-11 Body mass index; LIHC cis rs801193 0.761 rs2659888 chr7:66230171 T/G cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.63e-9 Aortic root size; LIHC cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.14 0.36 5.5e-12 Bipolar disorder; LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg05896524 chr21:47604654 C21orf56 -0.5 -7.95 -0.39 2.74e-14 Testicular germ cell tumor; LIHC cis rs10504073 0.647 rs10808744 chr8:49988984 A/G cg00325661 chr8:49890786 NA 0.33 7.53 0.38 4.44e-13 Blood metabolite ratios; LIHC cis rs6840360 0.533 rs13147021 chr4:152722688 A/C cg22705602 chr4:152727874 NA 0.4 8.35 0.41 1.67e-15 Intelligence (multi-trait analysis); LIHC cis rs950169 0.922 rs62021167 chr15:85118051 T/A cg12863693 chr15:85201151 NMB 0.44 6.14 0.32 2.28e-9 Schizophrenia; LIHC cis rs9309711 0.621 rs7586472 chr2:3473670 G/A cg15541040 chr2:3486749 NA -0.38 -5.88 -0.3 9.98e-9 Neurofibrillary tangles; LIHC cis rs6500602 0.727 rs4238849 chr16:4538114 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.3 0.32 8.98e-10 Schizophrenia; LIHC cis rs1580019 0.568 rs2122633 chr7:32523870 G/T cg07520158 chr7:32535189 LSM5;AVL9 0.56 8.16 0.4 6.48e-15 Cognitive ability; LIHC cis rs2997447 0.706 rs61776573 chr1:26429356 A/C cg19633962 chr1:26362018 EXTL1 -0.62 -6.82 -0.35 4.03e-11 QRS complex (12-leadsum); LIHC cis rs875971 1.000 rs4717292 chr7:65895598 G/A cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs600806 0.778 rs11101960 chr1:110008778 C/T cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.49 -0.33 3.08e-10 Intelligence (multi-trait analysis); LIHC cis rs2832191 0.791 rs7283853 chr21:30498515 G/A cg08807101 chr21:30365312 RNF160 -0.57 -8.87 -0.43 4.04e-17 Dental caries; LIHC cis rs4407350 1.000 rs4407350 chr22:44922275 G/A cg12001887 chr22:44893917 LDOC1L -0.34 -5.83 -0.3 1.28e-8 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.724 rs9347340 chr6:160188891 C/T cg11366901 chr6:160182831 ACAT2 -0.93 -16.46 -0.66 3.06e-45 Age-related macular degeneration (geographic atrophy); LIHC cis rs782590 0.748 rs782634 chr2:55897700 T/C cg18811423 chr2:55921094 PNPT1 0.84 12.96 0.57 1.57e-31 Metabolic syndrome; LIHC cis rs11676348 0.846 rs4674259 chr2:218991005 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.11 -0.31 2.78e-9 Ulcerative colitis; LIHC cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 11.6 0.53 1.82e-26 Alzheimer's disease; LIHC cis rs1348850 0.768 rs57681892 chr2:178357645 G/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.49 0.59 1.47e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs61990749 0.597 rs2299930 chr14:78163722 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.58 -9.64 -0.46 1.29e-19 Fibroblast growth factor basic levels; LIHC cis rs17401966 1.000 rs7530167 chr1:10453374 A/G cg19773385 chr1:10388646 KIF1B -0.45 -7.2 -0.36 3.92e-12 Hepatocellular carcinoma; LIHC cis rs1865721 0.771 rs7235563 chr18:73139335 C/G cg26385618 chr18:73139727 C18orf62 -0.32 -8.87 -0.43 4.18e-17 Intelligence; LIHC cis rs509477 0.718 rs273346 chr18:32603056 G/T cg23791764 chr18:32556832 MAPRE2 0.45 6.1 0.31 2.81e-9 Cerebrospinal fluid AB1-42 levels; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg06873352 chr17:61820015 STRADA 0.73 12.81 0.57 5.9e-31 Prudent dietary pattern; LIHC trans rs61931739 0.500 rs7308338 chr12:34553181 A/G cg26384229 chr12:38710491 ALG10B 0.63 8.19 0.4 5.37e-15 Morning vs. evening chronotype; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg09256448 chr16:638327 NA 0.39 6.78 0.34 5.38e-11 Height; LIHC cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.48 0.46 4.54e-19 Electroencephalogram traits; LIHC cis rs11229555 0.645 rs4347409 chr11:58176252 C/T cg15696309 chr11:58395628 NA 0.64 7.51 0.38 5.04e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7072216 0.727 rs942808 chr10:100168102 C/A cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC cis rs6088580 0.660 rs6087592 chr20:33114503 A/G cg08999081 chr20:33150536 PIGU 0.67 13.01 0.58 1e-31 Glomerular filtration rate (creatinine); LIHC cis rs7520050 0.966 rs6672898 chr1:46290588 G/A cg03146154 chr1:46216737 IPP -0.4 -6.54 -0.33 2.27e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7659604 0.540 rs116452657 chr4:122674147 A/G cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.7e-11 Type 2 diabetes; LIHC cis rs16828019 0.929 rs8179465 chr1:41701747 C/T cg03387723 chr1:41708464 SCMH1 -0.44 -7.22 -0.36 3.35e-12 Intelligence (multi-trait analysis); LIHC cis rs7582180 0.790 rs4851288 chr2:100920451 T/C cg14675211 chr2:100938903 LONRF2 0.53 7.98 0.4 2.29e-14 Intelligence (multi-trait analysis); LIHC cis rs7662987 0.517 rs2602873 chr4:100039032 G/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs700651 0.821 rs4850812 chr2:198743655 G/T cg03934865 chr2:198174659 NA -0.45 -6.49 -0.33 2.96e-10 Intracranial aneurysm; LIHC cis rs2361718 0.967 rs12942941 chr17:78103013 C/T cg09238746 chr17:78121135 EIF4A3 -0.47 -7.06 -0.36 9.51e-12 Yeast infection; LIHC cis rs73195822 0.614 rs73194057 chr12:111216913 T/C cg12870014 chr12:110450643 ANKRD13A 0.61 6.99 0.35 1.46e-11 Itch intensity from mosquito bite; LIHC cis rs911119 0.955 rs55897275 chr20:23595953 A/T cg16589663 chr20:23618590 CST3 0.72 7.6 0.38 2.88e-13 Chronic kidney disease; LIHC cis rs17376456 0.877 rs12716456 chr5:93397557 A/G cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs870825 0.616 rs36022027 chr4:185639192 C/T cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs6088590 0.735 rs6088618 chr20:33409350 G/A cg08999081 chr20:33150536 PIGU 0.52 8.86 0.43 4.58e-17 Coronary artery disease; LIHC cis rs7221595 0.825 rs10521127 chr17:3978268 A/G cg09597638 chr17:3907349 NA 0.49 6.92 0.35 2.3e-11 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; LIHC cis rs2012796 0.785 rs61986599 chr14:81860917 G/A cg02996355 chr14:81879375 NA 0.77 12.31 0.55 4.38e-29 Night sleep phenotypes; LIHC cis rs9733 0.596 rs72702536 chr1:150662574 C/T cg17724175 chr1:150552817 MCL1 0.48 9.76 0.47 5.25e-20 Tonsillectomy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14728310 chr19:9879317 ZNF846 0.51 7.1 0.36 7.11e-12 Lung function (FEV1/FVC); LIHC cis rs17818399 0.735 rs11894342 chr2:46836439 A/T cg02822958 chr2:46747628 ATP6V1E2 0.38 6.21 0.32 1.52e-9 Height; LIHC cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.28 -5.82 -0.3 1.33e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg11644478 chr21:40555479 PSMG1 -0.38 -5.97 -0.31 5.82e-9 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03965827 chr15:50979356 TRPM7 0.44 6.12 0.31 2.52e-9 Pancreatic cancer; LIHC cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg25894440 chr7:65020034 NA -0.55 -6.29 -0.32 9.65e-10 Diabetic kidney disease; LIHC cis rs11122272 0.735 rs2808592 chr1:231523757 G/A cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs1008375 1.000 rs1860597 chr4:17657650 C/T cg16339924 chr4:17578868 LAP3 0.45 6.35 0.32 6.94e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17376456 0.877 rs12716457 chr5:93397627 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs2806561 0.734 rs7548692 chr1:23354877 T/A cg12483005 chr1:23474871 LUZP1 0.45 6.85 0.35 3.51e-11 Height; LIHC cis rs11626933 0.959 rs8005973 chr14:90774951 C/T cg04374321 chr14:90722782 PSMC1 0.48 6.75 0.34 6.26e-11 Gut microbiota (bacterial taxa); LIHC cis rs7945705 0.846 rs2742540 chr11:8899528 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.45 8.01 0.4 1.84e-14 Hemoglobin concentration; LIHC cis rs6754311 0.593 rs55825471 chr2:136526981 T/A cg07305463 chr2:136567211 LCT 0.41 7.68 0.38 1.64e-13 Mosquito bite size; LIHC cis rs734999 0.524 rs4648448 chr1:2695687 C/T cg18854424 chr1:2615690 NA 0.33 7.15 0.36 5.13e-12 Ulcerative colitis; LIHC cis rs722599 0.599 rs3825708 chr14:75200697 C/T cg11812906 chr14:75593930 NEK9 0.37 5.77 0.3 1.73e-8 IgG glycosylation; LIHC cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg18357526 chr6:26021779 HIST1H4A 0.87 12.84 0.57 4.42e-31 Intelligence (multi-trait analysis); LIHC cis rs2280018 1.000 rs2280018 chr16:15150833 A/C cg27102117 chr16:15229624 NA 0.28 6.19 0.32 1.68e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs17331151 0.541 rs11709430 chr3:52862055 G/A cg04865290 chr3:52927548 TMEM110 -0.44 -6.35 -0.32 6.71e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg00091569 chr3:40428383 ENTPD3 0.42 6.93 0.35 2.12e-11 Renal cell carcinoma; LIHC trans rs1814175 0.817 rs10769598 chr11:49669326 C/G cg15704280 chr7:45808275 SEPT13 -0.99 -22.02 -0.77 1.5e-67 Height; LIHC cis rs7613875 0.521 rs4688754 chr3:50074641 G/T cg05623727 chr3:50126028 RBM5 -0.34 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs3960554 0.529 rs6465049 chr7:75874489 A/G cg01364799 chr7:75623366 TMEM120A -0.47 -6.78 -0.34 5.29e-11 Eotaxin levels; LIHC trans rs9388451 0.874 rs7739566 chr6:126094757 A/T cg05039488 chr6:79577232 IRAK1BP1 -0.54 -8.64 -0.42 2.13e-16 Brugada syndrome; LIHC cis rs10078 0.515 rs2672739 chr5:443447 A/C cg26072250 chr5:443457 EXOC3;C5orf55 0.72 9.28 0.45 1.97e-18 Fat distribution (HIV); LIHC cis rs4478858 0.684 rs10753245 chr1:31731208 A/G cg00250761 chr1:31883323 NA -0.28 -6.58 -0.34 1.74e-10 Alcohol dependence; LIHC trans rs1146361 0.556 rs983760 chr1:116676668 C/G cg20979128 chr1:16271176 ZBTB17 -0.46 -6.71 -0.34 8.1e-11 Fear of minor pain; LIHC cis rs34172651 0.517 rs200526 chr16:24760511 C/T cg00152838 chr16:24741724 TNRC6A 0.5 6.21 0.32 1.51e-9 Intelligence (multi-trait analysis); LIHC cis rs7727544 0.660 rs274563 chr5:131717859 C/A cg07395648 chr5:131743802 NA 0.31 6.49 0.33 3e-10 Blood metabolite levels; LIHC cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg21448741 chr8:58168803 NA 0.33 5.86 0.3 1.11e-8 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.754 rs10872580 chr6:146140281 C/T cg13319975 chr6:146136371 FBXO30 0.39 6.45 0.33 3.84e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs67460515 0.563 rs13071892 chr3:160817877 A/C cg03342759 chr3:160939853 NMD3 -0.61 -8.87 -0.43 4.15e-17 Parkinson's disease; LIHC cis rs7312933 0.558 rs1796394 chr12:42826359 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.56 -8.44 -0.42 9.35e-16 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9916302 0.861 rs752314 chr17:37410700 C/T cg07936489 chr17:37558343 FBXL20 -0.82 -13.46 -0.59 1.95e-33 Glomerular filtration rate (creatinine); LIHC cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg19729930 chr2:74357872 NA 0.83 18.34 0.7 8.29e-53 Gestational age at birth (maternal effect); LIHC cis rs9457247 1.000 rs405553 chr6:167395058 A/G cg23791538 chr6:167370224 RNASET2 -0.67 -11.6 -0.53 1.92e-26 Crohn's disease; LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.54e-15 Prudent dietary pattern; LIHC cis rs2180341 0.960 rs7773484 chr6:127670779 T/C cg27446573 chr6:127587934 RNF146 1.06 16.62 0.67 6.67e-46 Breast cancer; LIHC cis rs1997103 1.000 rs2331067 chr7:55408232 A/T cg17469321 chr7:55412551 NA 0.47 7.05 0.36 9.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs941408 1.000 rs1736182 chr19:2798686 T/G cg06609049 chr19:2785107 THOP1 0.61 9.61 0.46 1.69e-19 Total cholesterol levels; LIHC cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg08888203 chr3:10149979 C3orf24 0.61 6.59 0.34 1.65e-10 Alzheimer's disease; LIHC cis rs1075232 1.000 rs9672214 chr15:31677775 A/T cg01030201 chr15:31746330 NA -0.78 -6.09 -0.31 3.07e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs67478160 0.609 rs6576003 chr14:104291330 C/A cg08213375 chr14:104286397 PPP1R13B 0.51 9.64 0.46 1.34e-19 Schizophrenia; LIHC cis rs929354 0.713 rs6946660 chr7:156948648 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs11690935 0.959 rs10204502 chr2:172588866 C/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.77 -0.69 1.66e-50 Schizophrenia; LIHC cis rs1843834 0.734 rs1908251 chr2:225487865 T/C cg22509189 chr2:225307070 NA -0.57 -7.17 -0.36 4.59e-12 IgE levels in asthmatics (D.p. specific); LIHC trans rs600806 0.850 rs2303875 chr1:109955010 A/C cg12613107 chr7:150069577 REPIN1 0.81 6.04 0.31 4.08e-9 Intelligence (multi-trait analysis); LIHC trans rs10506458 0.834 rs73127067 chr12:63390333 G/T cg22491629 chr6:157744540 C6orf35 -0.61 -10.92 -0.51 4.95e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.51 0.56 7.86e-30 Prudent dietary pattern; LIHC cis rs9888615 0.624 rs12892879 chr14:53384621 G/A cg00686598 chr14:53173677 PSMC6 -0.46 -6.17 -0.32 1.9e-9 Systolic blood pressure; LIHC cis rs7903847 0.642 rs10786341 chr10:99158607 G/A cg20016023 chr10:99160130 RRP12 -0.42 -6.56 -0.33 1.95e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs7618501 0.521 rs868891 chr3:49949071 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.75 0.34 6.32e-11 Intelligence (multi-trait analysis); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg24115593 chr5:169010705 CCDC99 -0.39 -6.17 -0.32 1.97e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg23758822 chr17:41437982 NA 0.94 17.84 0.69 8.48e-51 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23129613 chr7:150065255 REPIN1 0.43 6.35 0.32 6.94e-10 Pancreatic cancer; LIHC cis rs7615952 0.736 rs11921945 chr3:125643719 A/G cg05084668 chr3:125655381 ALG1L -0.63 -9.17 -0.44 4.53e-18 Blood pressure (smoking interaction); LIHC cis rs3749237 0.595 rs4855873 chr3:49459114 A/C cg07636037 chr3:49044803 WDR6 0.52 8.12 0.4 8.6e-15 Resting heart rate; LIHC cis rs7116495 0.609 rs595062 chr11:71809635 C/T cg10381502 chr11:71823885 C11orf51 1.08 9.2 0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs921968 0.643 rs3932856 chr2:219320207 C/A cg02985541 chr2:219472218 PLCD4 0.47 9.08 0.44 8.56e-18 Mean corpuscular hemoglobin concentration; LIHC cis rs1401999 1.000 rs1533684 chr3:183635815 A/G cg01324343 chr3:183735012 ABCC5 0.72 11.68 0.53 9.45e-27 Anterior chamber depth; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26534993 chr2:3291401 TSSC1 0.47 6.5 0.33 2.77e-10 Hepatitis; LIHC cis rs11122272 0.735 rs2437150 chr1:231488524 A/G cg06096015 chr1:231504339 EGLN1 -0.47 -9.05 -0.44 1.13e-17 Hemoglobin concentration; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.54 0.8 2.06e-77 Prudent dietary pattern; LIHC cis rs8060686 0.641 rs28548264 chr16:68211321 A/G cg05110241 chr16:68378359 PRMT7 -0.51 -6.03 -0.31 4.14e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs9611519 0.929 rs926914 chr22:41418154 C/T cg03806693 chr22:41940476 POLR3H -0.71 -7.96 -0.4 2.52e-14 Neuroticism; LIHC cis rs9325144 0.647 rs12822023 chr12:39097964 T/C cg26384229 chr12:38710491 ALG10B -0.41 -5.89 -0.3 9.16e-9 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18683720 chr19:7694563 XAB2;LOC100131801 -0.48 -6.66 -0.34 1.07e-10 Pancreatic cancer; LIHC cis rs62179067 0.708 rs11896002 chr2:179935887 A/C cg07532576 chr2:179544947 TTN 0.61 5.8 0.3 1.49e-8 Late-onset Alzheimer's disease; LIHC cis rs10876993 0.928 rs2640631 chr12:58067532 A/T cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.07 -0.31 3.37e-9 Celiac disease or Rheumatoid arthritis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03574736 chr2:98280624 ACTR1B -0.57 -6.61 -0.34 1.49e-10 Systolic blood pressure; LIHC trans rs116095464 0.558 rs7736600 chr5:231337 A/C cg00938859 chr5:1591904 SDHAP3 0.57 7.04 0.36 1.03e-11 Breast cancer; LIHC cis rs6442522 0.678 rs878946 chr3:15509212 T/C cg16303742 chr3:15540471 COLQ 0.47 7.85 0.39 5.45e-14 Uric acid levels; LIHC trans rs875971 1.000 rs778706 chr7:65860424 A/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs7584330 0.910 rs6757376 chr2:238400036 G/C cg14458575 chr2:238380390 NA 0.38 6.17 0.32 1.95e-9 Prostate cancer; LIHC trans rs9929218 0.551 rs2296405 chr16:68721470 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.93 -22.79 -0.78 1.35e-70 Colorectal cancer; LIHC cis rs597539 0.652 rs627731 chr11:68698663 A/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.29 0.49 8.19e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs9641123 0.639 rs60811069 chr7:93212576 C/T cg09745688 chr16:2908918 PRSS22 -0.34 -6.17 -0.32 1.88e-9 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs1506636 0.962 rs629474 chr7:123399684 C/T cg03229431 chr7:123269106 ASB15 0.61 12.1 0.55 2.67e-28 Plateletcrit;Platelet count; LIHC cis rs11628318 0.588 rs12185065 chr14:103074636 A/C cg12046867 chr14:103022105 NA 0.44 7.01 0.35 1.26e-11 Platelet count; LIHC cis rs2279817 0.863 rs1416854 chr1:18024675 G/A cg21791023 chr1:18019539 ARHGEF10L 0.6 8.33 0.41 1.93e-15 Neuroticism; LIHC cis rs3806843 1.000 rs10066278 chr5:140156318 A/C cg26395211 chr5:140044315 WDR55 -0.42 -6.18 -0.32 1.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7707921 0.881 rs2407153 chr5:81555328 T/G cg15871215 chr5:81402204 ATG10 0.6 5.89 0.3 9.34e-9 Breast cancer; LIHC cis rs858239 0.699 rs1881201 chr7:23194013 C/T cg18081818 chr7:23246105 NA 0.44 6.75 0.34 6.49e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs4596713 0.538 rs11145484 chr9:71769857 G/C cg16512924 chr15:28394682 HERC2 0.4 6.42 0.33 4.66e-10 Headache; LIHC cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg10360323 chr17:41437877 NA 0.4 5.99 0.31 5.26e-9 Menopause (age at onset); LIHC cis rs12908161 0.959 rs17534709 chr15:85314397 G/C cg12863693 chr15:85201151 NMB 0.45 6.52 0.33 2.56e-10 Schizophrenia; LIHC cis rs7927592 0.513 rs901823 chr11:68205578 T/C cg01657329 chr11:68192670 LRP5 -0.55 -7.95 -0.4 2.67e-14 Total body bone mineral density; LIHC cis rs2292096 1.000 rs35687916 chr1:200725163 T/C cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.12 -0.31 2.57e-9 Epilepsy; LIHC cis rs1707322 0.686 rs3014239 chr1:46089801 G/A cg06784218 chr1:46089804 CCDC17 -0.43 -8.04 -0.4 1.43e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs240764 0.621 rs10457844 chr6:101196532 T/A cg09795085 chr6:101329169 ASCC3 -0.55 -7.86 -0.39 5.03e-14 Neuroticism; LIHC cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.67 11.01 0.51 2.56e-24 Menarche (age at onset); LIHC cis rs875971 0.545 rs35459055 chr7:65944386 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 7.02 0.35 1.21e-11 Aortic root size; LIHC cis rs5769765 0.818 rs8140681 chr22:50292081 C/A cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.23e-16 Schizophrenia; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.1 -0.31 2.91e-9 Total body bone mineral density; LIHC cis rs8062405 0.755 rs4788080 chr16:28558081 C/T cg07382826 chr16:28625726 SULT1A1 0.49 7.68 0.38 1.74e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg06238570 chr21:40685208 BRWD1 0.61 7.28 0.37 2.36e-12 Cognitive function; LIHC cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg18357526 chr6:26021779 HIST1H4A 0.58 8.04 0.4 1.49e-14 Blood metabolite levels; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg06873352 chr17:61820015 STRADA -0.71 -12.65 -0.56 2.36e-30 Prudent dietary pattern; LIHC cis rs911119 0.955 rs35610040 chr20:23616469 T/C cg16589663 chr20:23618590 CST3 0.76 7.89 0.39 4.24e-14 Chronic kidney disease; LIHC cis rs10420951 0.617 rs8103520 chr19:18563970 A/C cg10790698 chr19:18539756 SSBP4 -0.42 -6.03 -0.31 4.15e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4862750 0.914 rs11945845 chr4:187874136 T/C cg22105103 chr4:187893119 NA 0.32 7.85 0.39 5.32e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg02951883 chr7:2050386 MAD1L1 -0.56 -8.52 -0.42 5.05e-16 Bipolar disorder and schizophrenia; LIHC cis rs919433 0.680 rs7568250 chr2:198409611 G/A cg10820045 chr2:198174542 NA 0.54 8.58 0.42 3.33e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7619427 0.908 rs9882094 chr3:44081970 C/T cg24966902 chr3:44043705 NA 0.42 6.15 0.32 2.15e-9 Schizophrenia; LIHC trans rs7618501 0.573 rs7634917 chr3:50049299 T/G cg21659725 chr3:3221576 CRBN -0.71 -11.63 -0.53 1.39e-26 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg02993280 chr1:107599747 PRMT6 0.68 11.1 0.51 1.19e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs8078723 1.000 rs6503530 chr17:38161823 T/C cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.14 -0.44 5.58e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6988636 1.000 rs13260798 chr8:124190192 G/A cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs3808502 0.527 rs2736374 chr8:11113828 A/G cg22065733 chr8:11801320 NA 0.46 5.77 0.3 1.79e-8 Neuroticism; LIHC cis rs68170813 0.559 rs2249043 chr7:106960515 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.98 -0.31 5.76e-9 Coronary artery disease; LIHC cis rs35306767 0.761 rs11253537 chr10:1010735 G/A cg20503657 chr10:835505 NA 0.87 8.16 0.4 6.35e-15 Eosinophil percentage of granulocytes; LIHC cis rs858239 0.600 rs7776649 chr7:23119317 C/T cg23682824 chr7:23144976 KLHL7 0.44 6.4 0.33 5.14e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs17685 0.753 rs869804 chr7:75688954 A/G cg16684958 chr7:75615977 POR 0.51 8.51 0.42 5.6e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4819052 0.851 rs9974891 chr21:46680767 T/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 11.23 0.52 3.99e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4853012 0.838 rs2177707 chr2:74356850 A/G cg19729930 chr2:74357872 NA 0.84 18.8 0.71 1.23e-54 Gestational age at birth (maternal effect); LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg06873352 chr17:61820015 STRADA 0.71 12.2 0.55 1.17e-28 Prudent dietary pattern; LIHC cis rs7224737 1.000 rs11869069 chr17:40287101 C/G cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg21248554 chr2:27665150 KRTCAP3 -0.43 -6.03 -0.31 4.16e-9 Total body bone mineral density; LIHC cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08443851 chr16:85646773 KIAA0182 0.47 6.67 0.34 1e-10 Lung function (FEV1/FVC); LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg02951883 chr7:2050386 MAD1L1 -0.54 -8.13 -0.4 8.14e-15 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.57 0.33 1.92e-10 Schizophrenia; LIHC cis rs7395581 0.877 rs10838691 chr11:47341729 T/C cg25783544 chr11:47291846 MADD 0.4 5.74 0.3 2.04e-8 HDL cholesterol; LIHC trans rs4650994 0.544 rs2476560 chr1:178594919 A/G cg05059571 chr16:84539110 KIAA1609 0.41 6.83 0.35 3.81e-11 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg22800045 chr5:56110881 MAP3K1 0.67 8.53 0.42 4.66e-16 Initial pursuit acceleration; LIHC cis rs2242116 0.727 rs6442040 chr3:46963035 C/A cg16586182 chr3:47516702 SCAP -0.39 -6.67 -0.34 1e-10 Birth weight; LIHC trans rs7772697 0.635 rs4454159 chr6:149411908 A/C cg04561327 chr14:23540794 ACIN1 -0.52 -6.49 -0.33 3.08e-10 Diabetic retinopathy; LIHC cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg18357526 chr6:26021779 HIST1H4A 0.7 8.97 0.44 1.92e-17 Urate levels; LIHC cis rs12908161 0.959 rs1051168 chr15:85200520 G/T cg03959625 chr15:84868606 LOC388152 0.45 6.28 0.32 1.02e-9 Schizophrenia; LIHC cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.862 rs138857 chr22:50199589 C/T cg02269571 chr22:50332266 NA -0.64 -8.36 -0.41 1.59e-15 Schizophrenia; LIHC cis rs1670533 1.000 rs7673898 chr4:1056569 C/A cg27284194 chr4:1044797 NA 0.59 8.69 0.43 1.53e-16 Recombination rate (females); LIHC trans rs4650994 0.525 rs4651000 chr1:178532223 A/G cg05059571 chr16:84539110 KIAA1609 -0.45 -7.55 -0.38 3.99e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg11766577 chr21:47581405 C21orf56 -0.38 -5.9 -0.3 8.51e-9 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs9505467 chr6:8520219 G/A cg21535247 chr6:8435926 SLC35B3 0.63 8.31 0.41 2.3e-15 Motion sickness; LIHC cis rs35110281 0.776 rs2838338 chr21:45075582 T/C cg01579765 chr21:45077557 HSF2BP -0.34 -6.5 -0.33 2.87e-10 Mean corpuscular volume; LIHC cis rs34172651 0.517 rs2547040 chr16:24736408 G/C cg00152838 chr16:24741724 TNRC6A 0.49 6.12 0.31 2.6e-9 Intelligence (multi-trait analysis); LIHC cis rs7493 0.755 rs2375001 chr7:94964640 A/T cg21856205 chr7:94953877 PON1 -0.48 -6.17 -0.32 1.95e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs908922 0.676 rs578382 chr1:152514054 A/G cg20991723 chr1:152506922 NA -0.5 -8.6 -0.42 2.95e-16 Hair morphology; LIHC cis rs875971 0.964 rs778723 chr7:65829497 T/C cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs6835098 0.962 rs4419455 chr4:174083622 C/T cg27433088 chr4:174089019 GALNT7 -0.41 -6.59 -0.34 1.62e-10 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs2404602 0.569 rs2469249 chr15:76772062 C/T cg03037974 chr15:76606532 NA -0.59 -9.81 -0.47 3.43e-20 Blood metabolite levels; LIHC cis rs7617773 0.817 rs34225441 chr3:48308891 T/A cg11946769 chr3:48343235 NME6 0.9 10.96 0.51 3.69e-24 Coronary artery disease; LIHC cis rs427394 0.664 rs274696 chr5:6732213 A/C cg10857441 chr5:6722123 POLS -0.35 -6.06 -0.31 3.69e-9 Menopause (age at onset); LIHC cis rs1707322 0.721 rs10890336 chr1:46111056 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7131987 0.650 rs10843384 chr12:29472409 C/T cg05697976 chr12:29376483 FAR2 0.3 6.15 0.32 2.12e-9 QT interval; LIHC cis rs11645898 0.504 rs79489472 chr16:71870359 C/T cg03805757 chr16:71968109 PKD1L3 -0.85 -8.64 -0.42 2.13e-16 Blood protein levels; LIHC cis rs17685 0.725 rs4728548 chr7:75654632 A/T cg04610667 chr7:75704037 NA 0.32 5.79 0.3 1.61e-8 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs208520 0.770 rs1342960 chr6:66883514 T/C cg07460842 chr6:66804631 NA -0.76 -8.34 -0.41 1.89e-15 Exhaled nitric oxide output; LIHC cis rs7267979 1.000 rs4815417 chr20:25379526 C/T cg24626310 chr20:25276739 ABHD12;PYGB -0.45 -6.71 -0.34 7.96e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7945718 0.934 rs10831909 chr11:12817182 C/G cg25843174 chr11:12811716 TEAD1 0.37 8.12 0.4 8.5e-15 Educational attainment (years of education); LIHC cis rs7584330 0.744 rs58223447 chr2:238378644 G/C cg14458575 chr2:238380390 NA 0.55 7.85 0.39 5.47e-14 Prostate cancer; LIHC cis rs7772486 0.840 rs11155451 chr6:146422524 A/G cg23711669 chr6:146136114 FBXO30 0.64 10.8 0.5 1.37e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 0.929 rs799905 chr17:41277187 G/C cg05368731 chr17:41323189 NBR1 0.68 11.16 0.52 7.19e-25 Menopause (age at onset); LIHC cis rs7267979 0.966 rs4813557 chr20:25292545 C/T cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.77 -0.34 5.65e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs722599 0.599 rs3825708 chr14:75200697 C/T cg08847533 chr14:75593920 NEK9 0.44 6.88 0.35 2.8e-11 IgG glycosylation; LIHC cis rs7572733 0.555 rs6434954 chr2:198929716 T/C cg03934865 chr2:198174659 NA 0.44 6.27 0.32 1.07e-9 Dermatomyositis; LIHC cis rs875971 0.545 rs11766183 chr7:65839160 G/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 6.86 0.35 3.29e-11 Aortic root size; LIHC cis rs875971 0.545 rs4441996 chr7:65588220 T/C cg11764359 chr7:65958608 NA -0.51 -7.05 -0.36 1.02e-11 Aortic root size; LIHC cis rs8177253 0.965 rs8177260 chr3:133480458 T/A cg12373951 chr3:133503437 NA 0.7 12.72 0.57 1.29e-30 Iron status biomarkers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24924243 chr11:27528430 LIN7C;BDNFOS -0.41 -6.12 -0.31 2.56e-9 Pancreatic cancer; LIHC cis rs61990749 0.597 rs1549119 chr14:78219812 A/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.82 -0.39 6.67e-14 Fibroblast growth factor basic levels; LIHC cis rs4713118 0.586 rs6905522 chr6:28086479 A/C cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Parkinson's disease; LIHC cis rs1144333 0.655 rs76416835 chr1:76341511 G/T cg22875332 chr1:76189707 ACADM 0.43 6.41 0.33 4.77e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs12702595 0.589 rs6463662 chr7:7259477 G/A cg04827551 chr7:7268805 C1GALT1 0.33 6.15 0.32 2.16e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs1843834 0.898 rs2015099 chr2:225519915 T/C cg22509189 chr2:225307070 NA -0.54 -7.1 -0.36 7.19e-12 IgE levels in asthmatics (D.p. specific); LIHC cis rs240764 0.578 rs6925065 chr6:101178856 C/T cg12253828 chr6:101329408 ASCC3 0.42 6.69 0.34 9.19e-11 Neuroticism; LIHC cis rs17384381 0.953 rs12139958 chr1:85842112 A/G cg16011679 chr1:85725395 C1orf52 0.79 8.06 0.4 1.3e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs709400 0.663 rs7152202 chr14:103886757 A/G cg26031613 chr14:104095156 KLC1 0.73 9.93 0.47 1.44e-20 Body mass index; LIHC cis rs9902453 0.967 rs7222685 chr17:28496430 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.32 0.45 1.47e-18 Coffee consumption (cups per day); LIHC cis rs7326068 0.524 rs9506531 chr13:21232983 C/T cg27499820 chr13:21296301 IL17D -0.37 -5.74 -0.3 2.06e-8 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs2302190 1.000 rs7207286 chr17:56514458 A/C cg05425664 chr17:57184151 TRIM37 0.48 6.06 0.31 3.58e-9 Vitamin D levels; LIHC cis rs10420951 0.617 rs7251067 chr19:18600056 G/A cg10790698 chr19:18539756 SSBP4 -0.42 -5.99 -0.31 5.44e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs868036 0.672 rs7175517 chr15:68077630 A/G cg24579218 chr15:68104479 NA -0.34 -5.83 -0.3 1.27e-8 Restless legs syndrome; LIHC cis rs11233413 0.559 rs10898067 chr11:82684697 T/C cg24227371 chr11:82718527 RAB30 -0.35 -7.57 -0.38 3.59e-13 Economic and political preferences (feminism/equality); LIHC trans rs66887589 0.934 rs2389873 chr4:120554714 A/G cg25214090 chr10:38739885 LOC399744 -0.38 -6.16 -0.32 1.99e-9 Diastolic blood pressure; LIHC cis rs600806 0.778 rs891380 chr1:110003286 T/G cg23091122 chr1:110024289 SYPL2 -0.48 -6.32 -0.32 8.33e-10 Intelligence (multi-trait analysis); LIHC cis rs611744 0.506 rs13280454 chr8:109263240 A/G cg21045802 chr8:109455806 TTC35 0.59 10.51 0.49 1.41e-22 Dupuytren's disease; LIHC cis rs17102423 0.594 rs2781374 chr14:65568563 C/T cg16583315 chr14:65563665 MAX -0.42 -8.43 -0.41 9.65e-16 Obesity-related traits; LIHC cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg04944784 chr2:26401820 FAM59B 0.72 9.35 0.45 1.19e-18 Gut microbiome composition (summer); LIHC cis rs4665809 1.000 rs10202478 chr2:26276049 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.74 -9.21 -0.45 3.35e-18 Gut microbiome composition (summer); LIHC cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg03806693 chr22:41940476 POLR3H 1.14 13.44 0.59 2.41e-33 Vitiligo; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03729566 chr7:1059678 C7orf50 -0.41 -6.56 -0.33 1.97e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs12220238 1.000 rs10824075 chr10:75880254 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.53 0.33 2.33e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10216189 0.967 rs6962735 chr7:5526439 C/G cg05318486 chr7:5553423 FBXL18 -0.58 -8.63 -0.42 2.28e-16 Relative hand skill in reading disability; LIHC cis rs3096299 0.967 rs16965692 chr16:89471482 C/T cg01788221 chr16:89496183 ANKRD11 -0.39 -6.02 -0.31 4.51e-9 Multiple myeloma (IgH translocation); LIHC cis rs1878931 0.555 rs27228 chr16:3431933 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.21 -0.41 4.52e-15 Body mass index (adult); LIHC cis rs34779708 0.931 rs7920095 chr10:35303334 G/A cg03585969 chr10:35415529 CREM 0.86 13.15 0.58 2.91e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2286885 0.965 rs4837091 chr9:129244928 A/G cg15282417 chr9:129245246 FAM125B 0.41 6.86 0.35 3.25e-11 Intraocular pressure; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg04781839 chr16:1374937 UBE2I 0.36 6.05 0.31 3.75e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg12648201 chr2:27665141 KRTCAP3 -0.41 -5.77 -0.3 1.78e-8 Total body bone mineral density; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26912877 chr1:6305344 HES3 -0.47 -6.17 -0.32 1.98e-9 Systolic blood pressure; LIHC cis rs7944584 0.879 rs11039182 chr11:47346723 T/C cg20307385 chr11:47447363 PSMC3 0.63 6.4 0.33 5.07e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2404602 0.684 rs4886819 chr15:76901698 C/T cg23625390 chr15:77176239 SCAPER -0.53 -8.71 -0.43 1.32e-16 Blood metabolite levels; LIHC cis rs2841277 0.676 rs4264326 chr14:105411700 A/G cg15352829 chr14:105391018 PLD4 -0.45 -9.36 -0.45 1.1e-18 Rheumatoid arthritis; LIHC cis rs11758351 0.866 rs55815656 chr6:26207303 G/A cg23601095 chr6:26197514 HIST1H3D 0.54 5.79 0.3 1.58e-8 Gout;Renal underexcretion gout; LIHC cis rs1707322 0.963 rs1768815 chr1:46528603 G/A cg06784218 chr1:46089804 CCDC17 -0.37 -6.47 -0.33 3.43e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6542838 0.641 rs4850890 chr2:99535426 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.44 -6.42 -0.33 4.45e-10 Fear of minor pain; LIHC cis rs6089829 0.962 rs4586690 chr20:61658595 G/T cg08564027 chr20:61660810 NA 0.4 7.71 0.38 1.38e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs6500602 0.702 rs11076834 chr16:4549583 C/G cg09069446 chr16:4462122 CORO7 -0.35 -5.74 -0.3 2.04e-8 Schizophrenia; LIHC cis rs12477438 0.765 rs1054042 chr2:99614396 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -8.61 -0.42 2.65e-16 Chronic sinus infection; LIHC cis rs9611519 0.828 rs4822008 chr22:41539206 C/G cg03806693 chr22:41940476 POLR3H -0.7 -7.57 -0.38 3.56e-13 Neuroticism; LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg20295408 chr7:1910781 MAD1L1 -0.44 -6.42 -0.33 4.45e-10 Bipolar disorder and schizophrenia; LIHC cis rs8067545 0.750 rs35003563 chr17:19989218 G/A cg13482628 chr17:19912719 NA 0.49 8.24 0.41 3.68e-15 Schizophrenia; LIHC cis rs67981189 0.513 rs7154395 chr14:71566300 G/A cg15816911 chr14:71606274 NA 0.43 6.87 0.35 3.01e-11 Schizophrenia; LIHC cis rs79387448 0.638 rs7600961 chr2:103035455 G/A cg09003973 chr2:102972529 NA 1.11 9.76 0.47 5.07e-20 Gut microbiota (bacterial taxa); LIHC cis rs6952808 0.531 rs3779002 chr7:2183219 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.71 -0.3 2.46e-8 Bipolar disorder and schizophrenia; LIHC cis rs8017423 0.967 rs2277516 chr14:90722824 G/C cg14092571 chr14:90743983 NA -0.38 -6.03 -0.31 4.15e-9 Mortality in heart failure; LIHC cis rs1401999 0.932 rs4148557 chr3:183733784 A/G cg01324343 chr3:183735012 ABCC5 0.76 12.53 0.56 6.55e-30 Anterior chamber depth; LIHC trans rs62103177 0.535 rs62101568 chr18:77934671 G/A cg05926928 chr17:57297772 GDPD1 0.74 7.66 0.38 1.99e-13 Opioid sensitivity; LIHC cis rs36051895 0.623 rs1555476 chr9:5233054 T/C cg02405213 chr9:5042618 JAK2 -0.66 -10.06 -0.48 4.87e-21 Pediatric autoimmune diseases; LIHC trans rs7246657 0.882 rs10412043 chr19:37826626 A/C cg10208301 chr11:6592745 DNHD1 0.47 6.69 0.34 9.05e-11 Coronary artery calcification; LIHC cis rs7187994 0.848 rs16974558 chr16:84787111 G/A cg07647771 chr16:84786436 USP10 -0.32 -6.22 -0.32 1.47e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC trans rs11039798 1.000 rs7125913 chr11:48984318 G/A cg15704280 chr7:45808275 SEPT13 0.62 6.4 0.33 5.11e-10 Axial length; LIHC cis rs7395581 0.959 rs2279239 chr11:47281780 T/C cg26139080 chr11:47293733 MADD -0.5 -8.53 -0.42 4.94e-16 HDL cholesterol; LIHC cis rs738321 0.694 rs4821749 chr22:38542074 A/G cg25457927 chr22:38595422 NA -0.35 -7.84 -0.39 5.64e-14 Breast cancer; LIHC cis rs72829446 0.556 rs10048219 chr17:7403792 C/T cg02795151 chr17:7402630 POLR2A 0.51 5.75 0.3 2e-8 Androgen levels; LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg02290350 chr8:58132656 NA -0.49 -10.63 -0.5 5.43e-23 Developmental language disorder (linguistic errors); LIHC cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg10862848 chr6:42927986 GNMT -0.26 -6.34 -0.32 7.32e-10 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs7726839 0.540 rs11739847 chr5:609661 G/A cg25482853 chr8:67687455 SGK3 0.61 6.14 0.32 2.26e-9 Obesity-related traits; LIHC cis rs9549367 0.789 rs12584008 chr13:113881228 C/T cg00898013 chr13:113819073 PROZ -0.43 -7.46 -0.37 7.44e-13 Platelet distribution width; LIHC cis rs172166 0.694 rs203893 chr6:28062066 C/A cg16479474 chr6:28041457 NA 0.39 6.68 0.34 9.59e-11 Cardiac Troponin-T levels; LIHC cis rs9790314 0.687 rs1037888 chr3:160775251 A/T cg03342759 chr3:160939853 NMD3 -0.59 -7.3 -0.37 2.08e-12 Morning vs. evening chronotype; LIHC cis rs2075371 0.865 rs2544172 chr7:133931338 T/C cg11752832 chr7:134001865 SLC35B4 0.49 7.43 0.37 8.83e-13 Mean platelet volume; LIHC trans rs11098499 0.863 rs10013305 chr4:120450424 G/A cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg17178900 chr1:205818956 PM20D1 0.65 9.69 0.46 8.67e-20 Menarche (age at onset); LIHC cis rs12477438 0.715 rs7586608 chr2:99558017 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.1 -0.4 1.01e-14 Chronic sinus infection; LIHC cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg16434002 chr17:42200994 HDAC5 -0.52 -7.61 -0.38 2.76e-13 Total body bone mineral density; LIHC cis rs9473924 0.505 rs9473921 chr6:50828072 C/T cg14470998 chr6:50812995 TFAP2B 0.9 10.14 0.48 2.67e-21 Body mass index; LIHC cis rs7789940 0.904 rs61294900 chr7:75937212 A/T cg10167463 chr7:75959203 YWHAG -0.42 -6.39 -0.33 5.38e-10 Multiple sclerosis; LIHC cis rs5769765 0.908 rs9616396 chr22:50317825 T/C cg02269571 chr22:50332266 NA -0.66 -8.93 -0.43 2.72e-17 Schizophrenia; LIHC cis rs875971 0.545 rs1796219 chr7:66110964 A/G cg11764359 chr7:65958608 NA -0.56 -7.57 -0.38 3.6e-13 Aortic root size; LIHC cis rs477895 1.000 rs66968227 chr11:64070930 T/C cg18225595 chr11:63971243 STIP1 0.64 6.43 0.33 4.37e-10 Mean platelet volume; LIHC cis rs2072499 0.966 rs2842864 chr1:156159217 G/A cg24450063 chr1:156163899 SLC25A44 1.07 18.56 0.71 1.07e-53 Testicular germ cell tumor; LIHC cis rs4665809 1.000 rs10170359 chr2:26272219 G/T cg26119090 chr2:26468346 HADHA;HADHB -0.74 -9.21 -0.45 3.35e-18 Gut microbiome composition (summer); LIHC cis rs1707322 0.721 rs11211163 chr1:46153548 C/T cg03146154 chr1:46216737 IPP 0.6 10.26 0.49 1.04e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17106184 1.000 rs72900956 chr1:51143665 G/T cg07174182 chr1:51127561 FAF1 -0.76 -8.12 -0.4 8.47e-15 Type 2 diabetes; LIHC trans rs7336933 0.866 rs4941411 chr13:42471498 T/C cg15665968 chr21:44527764 U2AF1 -0.78 -6.16 -0.32 2.08e-9 Calcium levels; LIHC trans rs1814175 0.817 rs1794162 chr11:49899506 A/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg06481639 chr22:41940642 POLR3H 0.7 7.01 0.35 1.28e-11 Vitiligo; LIHC cis rs975210 1.000 rs975210 chr15:70364352 G/A cg01666796 chr15:70364327 TLE3 -0.59 -7.69 -0.38 1.54e-13 Height;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs9291683 0.588 rs4280729 chr4:10013861 C/T cg11266682 chr4:10021025 SLC2A9 0.33 7.05 0.36 9.84e-12 Bone mineral density; LIHC cis rs6089584 0.927 rs6089593 chr20:60572312 G/A cg06108461 chr20:60628389 TAF4 -0.87 -13.41 -0.59 3e-33 Body mass index; LIHC cis rs11190604 0.767 rs7076606 chr10:102192267 T/C cg07080220 chr10:102295463 HIF1AN 0.47 6.93 0.35 2.08e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7044106 0.708 rs920745 chr9:123429943 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.73 0.5 2.46e-23 Hip circumference adjusted for BMI; LIHC cis rs6754311 0.593 rs10195620 chr2:136495619 A/T cg07305463 chr2:136567211 LCT 0.39 7.25 0.37 2.76e-12 Mosquito bite size; LIHC cis rs7100689 0.646 rs2095994 chr10:82127956 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.706 rs7212621 chr17:37527911 T/G cg07936489 chr17:37558343 FBXL20 0.86 12.19 0.55 1.29e-28 Glomerular filtration rate (creatinine); LIHC cis rs7223966 1.000 rs7222060 chr17:61868279 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.76 0.34 5.99e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9790314 1.000 rs336590 chr3:161079583 G/A cg03342759 chr3:160939853 NMD3 -0.7 -8.34 -0.41 1.86e-15 Morning vs. evening chronotype; LIHC trans rs526821 0.595 rs4938937 chr11:55305507 T/A cg03929089 chr4:120376271 NA -0.48 -7.4 -0.37 1.08e-12 Pediatric bone mineral density (spine); LIHC cis rs7412746 0.611 rs10888391 chr1:150729983 G/A cg15448220 chr1:150897856 SETDB1 0.41 6.31 0.32 8.49e-10 Melanoma; LIHC cis rs7647973 0.626 rs11709734 chr3:49745235 G/A cg03060546 chr3:49711283 APEH 0.58 6.72 0.34 7.66e-11 Menarche (age at onset); LIHC cis rs10463316 0.894 rs7718085 chr5:150742957 G/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.41 -0.33 4.78e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7927592 0.956 rs7113287 chr11:68372186 A/T cg01657329 chr11:68192670 LRP5 -0.48 -6.39 -0.33 5.51e-10 Total body bone mineral density; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg02697074 chr17:40761760 FAM134C;TUBG1 0.38 6.05 0.31 3.72e-9 Metabolic traits; LIHC cis rs6840360 0.615 rs4696096 chr4:152475387 A/G cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs3106136 0.967 rs4693377 chr4:95157256 G/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.95 -0.39 2.81e-14 Capecitabine sensitivity; LIHC cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg19318889 chr4:1322082 MAEA 0.47 6.55 0.33 2.13e-10 Obesity-related traits; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg21747090 chr2:27597821 SNX17 -0.46 -6.89 -0.35 2.71e-11 Total body bone mineral density; LIHC cis rs6831352 0.918 rs17817359 chr4:100054197 G/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg20090690 chr10:134436459 INPP5A 0.42 5.8 0.3 1.5e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs6088580 0.524 rs6088552 chr20:33226491 A/G cg08999081 chr20:33150536 PIGU -0.43 -7.4 -0.37 1.07e-12 Glomerular filtration rate (creatinine); LIHC cis rs2404602 0.716 rs12917430 chr15:76674360 T/C cg23625390 chr15:77176239 SCAPER 0.37 6.05 0.31 3.9e-9 Blood metabolite levels; LIHC cis rs6545883 0.929 rs6705235 chr2:61713580 G/C cg15711740 chr2:61764176 XPO1 -0.42 -5.88 -0.3 9.51e-9 Tuberculosis; LIHC cis rs9902453 1.000 rs56280226 chr17:28429575 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.65 10.06 0.48 4.93e-21 Coffee consumption (cups per day); LIHC cis rs763121 0.853 rs5750652 chr22:39048316 A/G cg14440974 chr22:39074834 NA -0.35 -5.8 -0.3 1.51e-8 Menopause (age at onset); LIHC cis rs12995491 0.902 rs6737641 chr2:88529471 A/T cg14558114 chr2:88469736 THNSL2 -0.37 -5.76 -0.3 1.87e-8 Response to metformin (IC50); LIHC cis rs7937682 1.000 rs505372 chr11:111507189 A/C cg09085632 chr11:111637200 PPP2R1B -1.02 -12.17 -0.55 1.5e-28 Primary sclerosing cholangitis; LIHC cis rs2303745 0.622 rs1864113 chr19:17393504 G/C cg04248312 chr19:17393744 ANKLE1 -0.74 -12.4 -0.56 2.13e-29 Systemic lupus erythematosus; LIHC cis rs7617773 1.000 rs6771889 chr3:48194326 C/T cg11946769 chr3:48343235 NME6 -0.66 -8.46 -0.42 7.79e-16 Coronary artery disease; LIHC cis rs2832191 0.716 rs1984012 chr21:30392472 T/C cg08807101 chr21:30365312 RNF160 0.8 12.35 0.56 3.05e-29 Dental caries; LIHC cis rs6831352 0.840 rs17817868 chr4:100060623 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs8067545 0.750 rs11870111 chr17:19992738 G/A cg13482628 chr17:19912719 NA 0.48 8.09 0.4 1.03e-14 Schizophrenia; LIHC cis rs1865721 0.771 rs4622605 chr18:73139008 T/C cg26385618 chr18:73139727 C18orf62 -0.32 -8.58 -0.42 3.37e-16 Intelligence; LIHC cis rs61677309 1.000 rs56938099 chr11:118156688 A/G cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs892961 0.932 rs312853 chr17:75406045 T/G cg05865280 chr17:75406074 SEPT9 0.6 15.82 0.65 1.06e-42 Airflow obstruction; LIHC cis rs17854409 0.803 rs1048100 chr20:61472073 C/A cg06598544 chr20:61472147 COL9A3 -0.85 -8.18 -0.4 5.58e-15 Obesity-related traits; LIHC cis rs4076764 1.000 rs6683181 chr1:163417077 C/T cg24596788 chr1:163392923 NA -0.23 -7.17 -0.36 4.56e-12 Motion sickness; LIHC cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.01 -10.26 -0.49 1.02e-21 Platelet count; LIHC cis rs17253792 0.822 rs17832371 chr14:56162302 C/A cg01858014 chr14:56050164 KTN1 -0.71 -7.3 -0.37 1.98e-12 Putamen volume; LIHC cis rs7762018 0.607 rs79355059 chr6:170062157 T/C cg19338460 chr6:170058176 WDR27 -0.88 -9.6 -0.46 1.83e-19 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19173666 chr17:80740808 TBCD -0.33 -7.03 -0.36 1.13e-11 Calcium levels; LIHC cis rs35110281 0.626 rs162388 chr21:44936032 G/A cg04455712 chr21:45112962 RRP1B 0.42 7.15 0.36 5.45e-12 Mean corpuscular volume; LIHC cis rs1348850 0.526 rs6723063 chr2:178491398 C/T cg27490568 chr2:178487706 NA 1.25 14.78 0.62 1.38e-38 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7116495 0.867 rs529567 chr11:71580537 G/A cg26138937 chr11:71823887 C11orf51 0.7 6.86 0.35 3.3e-11 Severe influenza A (H1N1) infection; LIHC cis rs4862750 0.914 rs9995391 chr4:187873749 A/T cg10295955 chr4:187884368 NA 0.93 19.5 0.73 1.81e-57 Lobe attachment (rater-scored or self-reported); LIHC cis rs738321 0.723 rs9622726 chr22:38506688 A/G cg25457927 chr22:38595422 NA -0.31 -6.96 -0.35 1.73e-11 Breast cancer; LIHC cis rs75908454 1.000 rs16888015 chr6:169829597 A/G cg19338460 chr6:170058176 WDR27 -0.84 -7.59 -0.38 3.1e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs7091068 0.567 rs1572773 chr10:95432968 T/C cg20715218 chr10:95462985 C10orf4 0.53 7.69 0.38 1.5700000000000001e-13 Urinary tract infection frequency; LIHC cis rs2540917 0.904 rs2540916 chr2:60608930 T/C cg00543073 chr2:60773386 BCL11A -0.29 -5.83 -0.3 1.29e-8 Mean corpuscular volume; LIHC cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg09455208 chr3:40491958 NA 0.37 7.42 0.37 9.12e-13 Renal cell carcinoma; LIHC cis rs12477438 0.798 rs6736064 chr2:99658201 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.67 -0.53 1.03e-26 Chronic sinus infection; LIHC cis rs7659604 0.582 rs3217780 chr4:122737278 T/C cg19748678 chr4:122722346 EXOSC9 0.67 11.15 0.52 8.08e-25 Type 2 diabetes; LIHC cis rs1023500 0.506 rs6002625 chr22:42517689 A/G cg04733989 chr22:42467013 NAGA -0.64 -8.91 -0.43 3.18e-17 Schizophrenia; LIHC cis rs6545883 0.929 rs13413337 chr2:61747123 A/G cg15711740 chr2:61764176 XPO1 -0.44 -6.24 -0.32 1.27e-9 Tuberculosis; LIHC cis rs8103278 1.000 rs8108590 chr19:46301620 A/G cg02376097 chr19:46275166 DMPK -0.44 -6.82 -0.35 4.18e-11 Coronary artery disease; LIHC cis rs2279817 0.863 rs11203441 chr1:18026725 C/T cg21791023 chr1:18019539 ARHGEF10L 0.42 6.44 0.33 4.16e-10 Neuroticism; LIHC cis rs80282103 0.618 rs11250252 chr10:1124939 G/C cg08668510 chr10:1095578 IDI1 0.68 6.62 0.34 1.41e-10 Glomerular filtration rate (creatinine); LIHC cis rs9733 0.596 rs1136808 chr1:150702717 G/C cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs600806 0.713 rs10857786 chr1:110010110 C/G cg02415029 chr1:110025642 ATXN7L2 -0.49 -6.31 -0.32 8.63e-10 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.798 rs9679602 chr2:99577827 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.58 0.62 8.84e-38 Chronic sinus infection; LIHC cis rs796364 0.662 rs11688415 chr2:201143409 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.64 6.09 0.31 2.95e-9 Schizophrenia; LIHC cis rs13161895 1.000 rs34674199 chr5:179473900 G/A cg02702477 chr5:179499311 RNF130 0.8 11.17 0.52 6.67e-25 LDL cholesterol; LIHC cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg10862848 chr6:42927986 GNMT -0.28 -6.53 -0.33 2.32e-10 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs526821 0.595 rs551665 chr11:55343268 G/A cg03929089 chr4:120376271 NA -0.45 -6.85 -0.35 3.36e-11 Pediatric bone mineral density (spine); LIHC cis rs7903847 0.620 rs7923385 chr10:99117097 T/A cg20016023 chr10:99160130 RRP12 -0.4 -6.24 -0.32 1.27e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs12477438 0.684 rs6756880 chr2:99676991 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs10508774 0.929 rs56265142 chr10:32787643 A/G cg01819863 chr10:32635814 EPC1 0.61 5.8 0.3 1.49e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6062302 0.522 rs2236503 chr20:62224595 G/A cg09650180 chr20:62225654 GMEB2 -0.39 -6.01 -0.31 4.72e-9 Glioblastoma; LIHC cis rs9733 0.596 rs11586422 chr1:150679358 C/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs8062405 0.755 rs62034355 chr16:28581038 G/C cg07382826 chr16:28625726 SULT1A1 0.49 7.52 0.38 4.75e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12079745 0.793 rs12565852 chr1:169369330 T/A cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 2.01e-11 QT interval; LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg06656553 chr16:89960601 TCF25 -0.44 -5.91 -0.3 8.11e-9 Skin colour saturation; LIHC trans rs2749592 0.918 rs1208653 chr10:38253826 C/G cg17830980 chr10:43048298 ZNF37B 0.43 7.86 0.39 5.08e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9611565 0.592 rs5758405 chr22:42076381 C/A cg06634786 chr22:41940651 POLR3H 0.6 6.67 0.34 1.06e-10 Vitiligo; LIHC cis rs1270639 0.778 rs1796272 chr7:157437832 C/T cg05147654 chr7:157448565 PTPRN2 -0.3 -6.0 -0.31 5.11e-9 Colorectal cancer; LIHC cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg18876405 chr7:65276391 NA 0.55 9.39 0.45 8.39e-19 Calcium levels; LIHC trans rs1814175 0.646 rs1722010 chr11:49897958 A/G cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs7520050 0.581 rs6671303 chr1:46629653 A/C cg23431851 chr1:46668822 C1orf190;POMGNT1 -0.49 -7.76 -0.39 1e-13 Red blood cell count;Reticulocyte count; LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.21 0.55 1.05e-28 Height; LIHC cis rs9596863 1.000 rs9568943 chr13:54423065 G/T ch.13.53330881F chr13:54432880 NA 0.44 5.94 0.31 6.85e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15084945 chr3:39452455 SNORA62;RPSA -0.43 -6.48 -0.33 3.23e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs8072100 0.840 rs9912311 chr17:45547132 T/C cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.38 -6.02 -0.31 4.53e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2153535 0.580 rs9379206 chr6:8458021 C/A cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs2963155 0.518 rs853179 chr5:142634773 G/T cg17617527 chr5:142782415 NR3C1 0.93 10.31 0.49 7.26e-22 Breast cancer; LIHC cis rs3744061 0.520 rs9908979 chr17:74645486 T/G cg13533061 chr17:74712429 JMJD6 -0.3 -5.99 -0.31 5.46e-9 Retinal arteriolar caliber; LIHC cis rs1000083 0.651 rs56773447 chr5:96567642 G/T ch.5.96698337R chr5:96672581 NA 0.81 6.46 0.33 3.6e-10 Cisplatin-induced ototoxicity; LIHC cis rs1003719 0.788 rs11911508 chr21:38470504 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs3099143 0.908 rs3102716 chr15:77051003 T/G cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Recalcitrant atopic dermatitis; LIHC trans rs6598955 0.671 rs11247893 chr1:26597086 A/C cg07461501 chr17:79650226 HGS;ARL16 0.63 7.13 0.36 5.82e-12 Obesity-related traits; LIHC cis rs2153535 0.563 rs1796688 chr6:8536423 A/T cg07606381 chr6:8435919 SLC35B3 0.77 10.98 0.51 3.2e-24 Motion sickness; LIHC cis rs2153535 0.580 rs4960433 chr6:8523697 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.57 0.42 3.56e-16 Motion sickness; LIHC cis rs860295 0.812 rs12024257 chr1:155780536 G/A cg02153340 chr1:155202674 NA -0.34 -6.12 -0.31 2.56e-9 Body mass index; LIHC trans rs1814175 0.692 rs1851873 chr11:49937767 A/G cg18944383 chr4:111397179 ENPEP 0.24 6.15 0.32 2.16e-9 Height; LIHC cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg22907277 chr7:1156413 C7orf50 0.58 8.79 0.43 7.41e-17 Longevity;Endometriosis; LIHC cis rs763121 0.853 rs6001188 chr22:39062194 T/C cg06022373 chr22:39101656 GTPBP1 0.66 11.49 0.53 4.72e-26 Menopause (age at onset); LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg01411255 chr17:61851458 DDX42;CCDC47 1.01 21.76 0.76 1.63e-66 Height; LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg09177884 chr7:1199841 ZFAND2A -0.41 -5.9 -0.3 8.56e-9 Longevity;Endometriosis; LIHC cis rs2412488 0.853 rs10011394 chr4:54355067 C/T cg22241045 chr4:54363911 LNX1 0.41 6.7 0.34 8.67e-11 DNA methylation (variation); LIHC cis rs9916302 0.904 rs4795357 chr17:37569551 T/C cg07936489 chr17:37558343 FBXL20 -0.82 -13.01 -0.58 1e-31 Glomerular filtration rate (creatinine); LIHC cis rs2839186 0.770 rs2839984 chr21:47671690 A/G cg05896524 chr21:47604654 C21orf56 0.51 8.07 0.4 1.17e-14 Testicular germ cell tumor; LIHC cis rs875971 0.862 rs2901152 chr7:65765004 G/A cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs2439831 1.000 rs2444032 chr15:43755346 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.89 0.43 3.51e-17 Lung cancer in ever smokers; LIHC cis rs12477438 1.000 rs11897712 chr2:99735697 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -7.83 -0.39 6.2e-14 Chronic sinus infection; LIHC cis rs36051895 0.659 rs3780365 chr9:5068520 T/C cg02405213 chr9:5042618 JAK2 -0.71 -12.31 -0.55 4.49e-29 Pediatric autoimmune diseases; LIHC trans rs2243480 1.000 rs160634 chr7:65528664 C/T cg10756647 chr7:56101905 PSPH -1.0 -12.98 -0.57 1.32e-31 Diabetic kidney disease; LIHC cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg23221052 chr5:179740743 GFPT2 -0.41 -5.9 -0.3 8.71e-9 Height; LIHC cis rs9318086 0.935 rs9652080 chr13:24435426 A/C cg25267304 chr13:24462978 PCOTH;MIPEP -0.54 -10.79 -0.5 1.45e-23 Myopia (pathological); LIHC cis rs2191566 1.000 rs7256908 chr19:44528898 C/T cg18700516 chr19:44507157 ZNF230 -0.36 -5.97 -0.31 6.07e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs7914558 1.000 rs7071373 chr10:104771922 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.75 -0.43 9.58e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs17152411 0.793 rs7085829 chr10:126587142 A/G cg07906193 chr10:126599966 NA 0.42 6.61 0.34 1.48e-10 Height; LIHC cis rs9517313 0.615 rs4772079 chr13:99090837 C/G cg20487152 chr13:99095054 FARP1 -0.49 -8.84 -0.43 5.11e-17 Neuroticism; LIHC cis rs4407350 0.870 rs5765715 chr22:44915217 A/G cg26276947 chr22:44892394 LDOC1L 0.34 6.39 0.33 5.35e-10 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.573 rs28779471 chr17:29084369 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 8.11e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs151997 0.925 rs26090 chr5:50170071 C/T cg06027927 chr5:50259733 NA -0.56 -7.51 -0.38 5.03e-13 Callous-unemotional behaviour; LIHC cis rs34779708 0.931 rs12248333 chr10:35362977 A/G cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.47e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3806843 0.966 rs7737424 chr5:140146345 C/T cg26395211 chr5:140044315 WDR55 -0.4 -5.97 -0.31 5.79e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7131987 0.650 rs16934135 chr12:29483963 T/G cg00204748 chr12:29376779 FAR2 0.4 7.48 0.38 6.14e-13 QT interval; LIHC cis rs7829975 0.623 rs10087493 chr8:8373557 A/G cg06636001 chr8:8085503 FLJ10661 -0.52 -8.39 -0.41 1.27e-15 Mood instability; LIHC trans rs7618501 0.521 rs34654589 chr3:49911449 C/G cg21659725 chr3:3221576 CRBN 0.56 8.0 0.4 2.01e-14 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.773 rs309176 chr2:136622216 T/C cg25344623 chr2:136566232 LCT 0.41 8.48 0.42 6.85e-16 Mosquito bite size; LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.97 -22.38 -0.77 5.51e-69 Prudent dietary pattern; LIHC cis rs7582720 1.000 rs72926781 chr2:203808835 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs8058578 0.887 rs28421305 chr16:30838128 G/A cg00531865 chr16:30841666 NA -0.4 -6.07 -0.31 3.48e-9 Multiple myeloma; LIHC cis rs9948 0.655 rs62152771 chr2:97447121 C/G cg01990225 chr2:97406019 LMAN2L -0.83 -6.43 -0.33 4.41e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs11098499 0.954 rs11734241 chr4:120416872 A/G cg09307838 chr4:120376055 NA 0.77 12.25 0.55 7.23e-29 Corneal astigmatism; LIHC trans rs911555 0.755 rs975892 chr14:103883349 A/T cg17675199 chr6:35436792 RPL10A 0.42 8.68 0.42 1.68e-16 Intelligence (multi-trait analysis); LIHC cis rs9814567 0.806 rs9824185 chr3:134324024 G/C cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.8 -0.3 1.53e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1008375 0.966 rs6449313 chr4:17588320 A/G cg02297831 chr4:17616191 MED28 0.42 5.8 0.3 1.53e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7089973 0.624 rs10885613 chr10:116589400 G/A cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs10504229 0.610 rs7011877 chr8:58147181 C/T cg02290350 chr8:58132656 NA 0.44 9.28 0.45 2.02e-18 Developmental language disorder (linguistic errors); LIHC cis rs6456156 0.586 rs2001114 chr6:167486578 A/G cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.06e-9 Primary biliary cholangitis; LIHC cis rs7829975 0.688 rs7827182 chr8:8380471 C/G cg06636001 chr8:8085503 FLJ10661 0.49 7.92 0.39 3.36e-14 Mood instability; LIHC cis rs7572733 0.534 rs1464211 chr2:198798630 G/A cg00792783 chr2:198669748 PLCL1 0.46 6.86 0.35 3.19e-11 Dermatomyositis; LIHC cis rs7945705 0.818 rs2653613 chr11:8879105 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -9.34 -0.45 1.27e-18 Hemoglobin concentration; LIHC cis rs9660180 0.620 rs34298494 chr1:1663402 A/C cg23982607 chr1:1823379 GNB1 0.49 7.0 0.35 1.33e-11 Body mass index; LIHC cis rs4891159 0.790 rs9950025 chr18:74113596 C/G cg24786174 chr18:74118243 ZNF516 0.78 14.41 0.61 3.99e-37 Longevity; LIHC cis rs11628318 0.853 rs10151896 chr14:103039936 G/C cg12046867 chr14:103022105 NA -0.57 -8.43 -0.41 9.98e-16 Platelet count; LIHC cis rs7961581 0.912 rs4760915 chr12:71634112 T/C cg05756094 chr12:71608604 NA 0.37 5.77 0.3 1.82e-8 Type 2 diabetes; LIHC cis rs9326248 1.000 rs4938354 chr11:117051165 A/G cg10130564 chr11:117069849 TAGLN 0.35 6.01 0.31 4.84e-9 Blood protein levels; LIHC trans rs6952808 0.692 rs59619245 chr7:2068630 C/T cg04565464 chr8:145669602 NFKBIL2 0.4 6.67 0.34 1.05e-10 Bipolar disorder and schizophrenia; LIHC cis rs11122272 0.735 rs2486745 chr1:231505717 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.26 -0.49 1.05e-21 Hemoglobin concentration; LIHC cis rs17286411 0.787 rs1834036 chr16:71972060 G/A cg06353428 chr16:71660113 MARVELD3 0.51 6.5 0.33 2.87e-10 Blood protein levels; LIHC cis rs6867032 1.000 rs4975796 chr5:2015520 A/T cg26168224 chr5:2018326 NA -0.3 -7.44 -0.37 8.33e-13 Gut microbiome composition (winter); LIHC cis rs11626933 1.000 rs59905513 chr14:90749638 T/C cg14092571 chr14:90743983 NA -0.9 -14.86 -0.63 6.84e-39 Gut microbiota (bacterial taxa); LIHC cis rs986417 0.748 rs10145546 chr14:61100892 A/G cg27398547 chr14:60952738 C14orf39 0.67 7.41 0.37 1.03e-12 Gut microbiota (bacterial taxa); LIHC cis rs7937890 0.668 rs12361851 chr11:14267668 C/T cg02886208 chr11:14281011 SPON1 0.5 6.81 0.35 4.44e-11 Mitochondrial DNA levels; LIHC cis rs4423214 1.000 rs12792306 chr11:71166992 T/C cg05163923 chr11:71159392 DHCR7 0.86 13.38 0.59 3.95e-33 Vitamin D levels; LIHC cis rs9814567 1.000 rs11928499 chr3:134232350 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2066819 1.000 rs80317430 chr12:56727705 G/A cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs7716219 0.572 rs3898451 chr5:54875243 C/A cg14753740 chr5:54468940 CDC20B;MIR449C 0.44 6.13 0.31 2.42e-9 Height; LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg07677032 chr17:61819896 STRADA 0.41 6.04 0.31 4.02e-9 Prudent dietary pattern; LIHC cis rs11112613 0.818 rs73184093 chr12:106010066 G/C cg03607813 chr12:105948248 NA 0.49 7.35 0.37 1.46e-12 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs2933343 0.679 rs789229 chr3:128602526 C/T cg25356066 chr3:128598488 ACAD9 0.55 7.7 0.38 1.51e-13 IgG glycosylation; LIHC cis rs7100689 0.753 rs4934125 chr10:82147466 T/C cg01528321 chr10:82214614 TSPAN14 0.89 12.81 0.57 6.08e-31 Post bronchodilator FEV1; LIHC trans rs11146838 1 rs11146838 chr10:39149977 A/T cg04469686 chr1:162760199 HSD17B7 -0.42 -6.42 -0.33 4.48e-10 Breast cancer; LIHC cis rs7945071 0.507 rs12417004 chr11:110297827 T/C cg04157658 chr11:110243994 NA 0.34 6.14 0.32 2.26e-9 Cognitive function; LIHC trans rs2797160 1.000 rs9491471 chr6:125991715 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.43 -6.31 -0.32 8.59e-10 Endometrial cancer; LIHC cis rs7249142 0.549 rs7260127 chr19:19280499 C/T cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B 0.42 7.04 0.36 1.04e-11 IgG glycosylation; LIHC cis rs2932538 0.922 rs6537744 chr1:113096746 C/G cg22162597 chr1:113214053 CAPZA1 0.69 10.66 0.5 4.37e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1023500 0.573 rs133374 chr22:42465941 G/A cg15557168 chr22:42548783 NA -0.42 -6.69 -0.34 8.95e-11 Schizophrenia; LIHC cis rs36051895 0.659 rs67006981 chr9:5070401 A/G cg02405213 chr9:5042618 JAK2 -0.68 -11.22 -0.52 4.45e-25 Pediatric autoimmune diseases; LIHC cis rs11764590 0.666 rs3996325 chr7:2053747 T/C cg23422044 chr7:1970798 MAD1L1 -0.58 -9.01 -0.44 1.49e-17 Neuroticism; LIHC cis rs12286929 0.600 rs4445669 chr11:115045237 C/T cg04055981 chr11:115044050 NA -0.52 -8.41 -0.41 1.12e-15 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2404602 0.647 rs7178250 chr15:77099107 T/C cg23625390 chr15:77176239 SCAPER -0.56 -9.55 -0.46 2.59e-19 Blood metabolite levels; LIHC trans rs3820928 0.605 rs6718767 chr2:227800776 A/G cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.62e-9 Pulmonary function; LIHC cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg02290350 chr8:58132656 NA 0.47 8.49 0.42 6.54e-16 Developmental language disorder (linguistic errors); LIHC cis rs4969178 0.965 rs56658017 chr17:76396164 G/A cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs8014204 0.604 rs7156590 chr14:75388183 C/T cg08847533 chr14:75593920 NEK9 0.43 7.09 0.36 7.92e-12 Caffeine consumption; LIHC cis rs7927592 0.913 rs10896329 chr11:68250029 A/G cg16797656 chr11:68205561 LRP5 0.54 8.65 0.42 2.08e-16 Total body bone mineral density; LIHC cis rs7662987 0.517 rs1154410 chr4:100006645 A/G cg12011299 chr4:100065546 ADH4 0.62 10.07 0.48 4.63e-21 Smoking initiation; LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg22903471 chr2:27725779 GCKR -0.52 -8.98 -0.44 1.79e-17 Total body bone mineral density; LIHC cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg05665937 chr4:1216051 CTBP1 0.45 6.0 0.31 4.97e-9 Obesity-related traits; LIHC cis rs10493773 1.000 rs12754358 chr1:86248431 C/T cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.39 -0.37 1.17e-12 Urate levels in overweight individuals; LIHC cis rs4788570 0.697 rs11075904 chr16:71816899 G/A cg06353428 chr16:71660113 MARVELD3 1.33 14.27 0.61 1.38e-36 Intelligence (multi-trait analysis); LIHC cis rs736408 0.812 rs2071507 chr3:52826707 G/A cg18404041 chr3:52824283 ITIH1 -0.64 -10.3 -0.49 7.49e-22 Bipolar disorder; LIHC cis rs3806843 0.766 rs801399 chr5:140034844 C/T cg19875535 chr5:140030758 IK -0.39 -6.3 -0.32 8.93e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs79149102 0.579 rs12593476 chr15:75282092 A/C cg16226627 chr15:75307476 SCAMP5 0.56 9.81 0.47 3.65e-20 Lung cancer; LIHC cis rs3736485 0.903 rs8039835 chr15:51865864 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.07 -0.31 3.46e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs35306767 0.903 rs12769431 chr10:922633 T/C cg20503657 chr10:835505 NA 1.01 12.03 0.55 4.92e-28 Eosinophil percentage of granulocytes; LIHC cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg18230493 chr5:56204884 C5orf35 -0.43 -6.0 -0.31 4.91e-9 Initial pursuit acceleration; LIHC cis rs7772486 0.686 rs9497395 chr6:146013592 A/G cg23711669 chr6:146136114 FBXO30 -0.61 -10.12 -0.48 3.11e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs3845702 0.736 rs6733426 chr2:180830958 A/G cg01881094 chr2:180872142 CWC22 -1.13 -10.41 -0.49 3.17e-22 Schizophrenia; LIHC cis rs748404 0.560 rs1869258 chr15:43803621 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.34 0.37 1.57e-12 Lung cancer; LIHC cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg22105103 chr4:187893119 NA 0.35 8.82 0.43 6.11e-17 Lobe attachment (rater-scored or self-reported); LIHC trans rs916888 0.821 rs199506 chr17:44859031 A/G cg26692224 chr17:62915920 LRRC37A3 0.67 6.48 0.33 3.22e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2404602 0.692 rs8043474 chr15:76974723 T/C cg03037974 chr15:76606532 NA 0.74 14.5 0.62 1.86e-37 Blood metabolite levels; LIHC cis rs1577917 1.000 rs12207610 chr6:86688016 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.77 -0.47 4.66e-20 Response to antipsychotic treatment; LIHC cis rs11719291 0.833 rs34037363 chr3:48821036 C/T cg00383909 chr3:49044727 WDR6 0.92 7.72 0.39 1.26e-13 Cognitive function; LIHC cis rs2070488 0.804 rs7372452 chr3:38444298 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.62 9.5 0.46 3.91e-19 Electrocardiographic conduction measures; LIHC cis rs10847980 0.590 rs75794148 chr12:123287329 C/G cg22842854 chr12:123319900 HIP1R 0.91 9.9 0.47 1.79e-20 Adiponectin levels; LIHC cis rs875971 0.545 rs6969224 chr7:65834998 T/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 6.83 0.35 3.79e-11 Aortic root size; LIHC cis rs651907 0.535 rs11717638 chr3:101505468 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.6e-18 Bipolar disorder; LIHC cis rs1865760 0.929 rs2876693 chr6:25954434 C/G cg15691649 chr6:25882328 NA -0.37 -5.9 -0.3 8.57e-9 Height; LIHC cis rs992157 0.560 rs10932763 chr2:219085863 G/C cg00012203 chr2:219082015 ARPC2 -0.87 -15.23 -0.64 2.51e-40 Colorectal cancer; LIHC cis rs2274273 0.870 rs4597235 chr14:55851987 A/G cg04306507 chr14:55594613 LGALS3 0.32 5.94 0.31 7.04e-9 Protein biomarker; LIHC cis rs6089584 0.526 rs6089619 chr20:60610916 C/T cg06108461 chr20:60628389 TAF4 -0.61 -8.36 -0.41 1.65e-15 Body mass index; LIHC cis rs400736 0.930 rs370812 chr1:8075894 C/T cg25007680 chr1:8021821 PARK7 0.59 9.58 0.46 2.03e-19 Response to antidepressants and depression; LIHC trans rs3749237 1.000 rs2307021 chr3:49765483 C/G cg21659725 chr3:3221576 CRBN 0.79 12.3 0.55 4.68e-29 Resting heart rate; LIHC cis rs17106184 1.000 rs113611257 chr1:51221103 G/A cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs17401966 0.898 rs11587495 chr1:10448999 T/C cg15208524 chr1:10270712 KIF1B 0.39 5.72 0.3 2.35e-8 Hepatocellular carcinoma; LIHC cis rs716804 0.566 rs9645625 chr11:10070833 A/C cg01453529 chr11:10209919 SBF2 -0.32 -6.12 -0.31 2.57e-9 Neuroticism; LIHC cis rs644799 0.710 rs519511 chr11:95538270 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.64 0.56 2.6e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs11098499 1.000 rs3749591 chr4:120214030 T/G cg25214090 chr10:38739885 LOC399744 0.52 7.98 0.4 2.16e-14 Corneal astigmatism; LIHC cis rs2282526 0.615 rs463738 chr21:44921166 G/A cg04455712 chr21:45112962 RRP1B -0.46 -7.19 -0.36 4.17e-12 Mean corpuscular hemoglobin; LIHC cis rs919433 0.783 rs788014 chr2:198228997 G/A cg03934865 chr2:198174659 NA 0.55 8.42 0.41 1.08e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg24209194 chr3:40518798 ZNF619 0.45 6.46 0.33 3.7e-10 Renal cell carcinoma; LIHC cis rs798554 0.757 rs1182177 chr7:2874540 C/T cg04166393 chr7:2884313 GNA12 0.49 6.58 0.34 1.75e-10 Height; LIHC cis rs12824058 0.678 rs11614163 chr12:130814621 C/G cg24229701 chr12:130821962 PIWIL1 0.43 6.28 0.32 1e-9 Menopause (age at onset); LIHC cis rs9733 0.543 rs72702558 chr1:150683251 G/A cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs208520 1.000 rs12190316 chr6:66973365 T/C cg07460842 chr6:66804631 NA 0.66 6.97 0.35 1.65e-11 Exhaled nitric oxide output; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg11494091 chr17:61959527 GH2 0.46 8.29 0.41 2.69e-15 Prudent dietary pattern; LIHC cis rs9303401 0.659 rs7210432 chr17:56668170 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.34 0.58 5.79e-33 Cognitive test performance; LIHC cis rs16958440 0.867 rs77615793 chr18:44684464 C/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs10540 1.000 rs61876326 chr11:467368 A/G cg03352830 chr11:487213 PTDSS2 0.67 6.05 0.31 3.71e-9 Body mass index; LIHC trans rs12478296 0.901 rs7420176 chr2:243005277 G/A cg01596870 chr19:55963115 NA -0.68 -9.92 -0.47 1.45e-20 Obesity-related traits; LIHC cis rs6546550 0.901 rs1979214 chr2:70137498 G/C cg02498382 chr2:70120550 SNRNP27 -0.44 -7.61 -0.38 2.69e-13 Prevalent atrial fibrillation; LIHC trans rs11098499 0.754 rs7672372 chr4:120248406 A/G cg25214090 chr10:38739885 LOC399744 0.52 8.39 0.41 1.3e-15 Corneal astigmatism; LIHC cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 11.87 0.54 1.85e-27 Colorectal cancer; LIHC cis rs240764 0.658 rs10457077 chr6:101196767 C/T cg09795085 chr6:101329169 ASCC3 -0.45 -6.68 -0.34 9.69e-11 Neuroticism; LIHC trans rs1499614 1.000 rs2707840 chr7:66158015 C/T cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs876084 0.505 rs9969404 chr8:121107102 A/C cg06265175 chr8:121136014 COL14A1 0.48 7.72 0.39 1.34e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21512275 chr2:157198069 NA 0.45 6.82 0.35 4.11e-11 Cognitive function; LIHC cis rs6088580 0.634 rs6087577 chr20:32955423 C/T cg08999081 chr20:33150536 PIGU 0.64 12.99 0.57 1.28e-31 Glomerular filtration rate (creatinine); LIHC trans rs3749237 0.964 rs1799843 chr3:49849723 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.63 9.65 0.46 1.24e-19 Resting heart rate; LIHC cis rs74417235 0.684 rs13185173 chr5:154055081 A/G cg08893839 chr5:154027129 NA 0.49 6.75 0.34 6.16e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC trans rs1005277 0.579 rs2749616 chr10:38510993 A/T cg27523141 chr10:43048294 ZNF37B 0.38 6.42 0.33 4.69e-10 Extrinsic epigenetic age acceleration; LIHC cis rs763014 0.966 rs35642938 chr16:642249 T/C cg04709771 chr16:646395 RAB40C 0.44 8.02 0.4 1.7e-14 Height; LIHC cis rs6089584 0.888 rs2181590 chr20:60622843 T/C cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC cis rs67460515 0.563 rs73023235 chr3:160864123 G/A cg17135325 chr3:160939158 NMD3 0.57 7.96 0.4 2.62e-14 Parkinson's disease; LIHC cis rs4950322 0.512 rs10736839 chr1:146842146 C/G cg25205988 chr1:146714368 CHD1L 0.44 6.29 0.32 9.91e-10 Protein quantitative trait loci; LIHC cis rs7216064 0.589 rs7213585 chr17:66062316 A/T cg12091567 chr17:66097778 LOC651250 -0.86 -14.44 -0.62 3.07e-37 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs801193 0.839 rs6968619 chr7:66068867 T/C cg18876405 chr7:65276391 NA -0.41 -7.34 -0.37 1.58e-12 Aortic root size; LIHC cis rs911119 0.955 rs6048952 chr20:23607257 A/G cg16589663 chr20:23618590 CST3 0.71 7.51 0.38 5.15e-13 Chronic kidney disease; LIHC cis rs35740288 0.539 rs11634553 chr15:86336611 G/A cg20737812 chr15:86336631 KLHL25 -0.42 -5.83 -0.3 1.27e-8 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs7917772 0.536 rs4919667 chr10:104426011 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.73 -9.28 -0.45 1.95e-18 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4822044 0.560 rs7284839 chr22:42010902 C/T cg06634786 chr22:41940651 POLR3H 0.71 7.4 0.37 1.09e-12 Cannabis dependence symptom count; LIHC cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg07424592 chr7:64974309 NA 0.79 9.1 0.44 7.54e-18 Diabetic kidney disease; LIHC cis rs5770917 1.000 rs3180872 chr22:51017394 G/C cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.49 -6.05 -0.31 3.79e-9 Narcolepsy; LIHC cis rs8060686 0.641 rs7192187 chr16:68132109 T/C cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.69e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs11098499 0.954 rs35063680 chr4:120387102 T/C cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg27572855 chr1:25598939 RHD -0.39 -8.48 -0.42 6.88e-16 Erythrocyte sedimentation rate; LIHC cis rs11718455 0.960 rs1852037 chr3:44003720 G/T cg08738300 chr3:44038990 NA -0.5 -8.47 -0.42 7.44e-16 Coronary artery disease; LIHC cis rs12479064 0.724 rs11885942 chr2:100004165 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -8.71 -0.43 1.35e-16 Chronic sinus infection; LIHC cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg18225595 chr11:63971243 STIP1 0.65 10.33 0.49 5.81e-22 Platelet count; LIHC cis rs12497850 0.931 rs9755490 chr3:48871664 A/C cg06212747 chr3:49208901 KLHDC8B 0.55 7.07 0.36 8.98e-12 Parkinson's disease; LIHC trans rs5743467 1.000 rs5743467 chr8:6731529 C/G cg14033944 chr8:11627058 NEIL2 -0.6 -6.4 -0.33 5.09e-10 Plasma kynurenine levels in major depressive disorder;Plasma kynurenine to tryptophan ratio in major depressive disorder; LIHC cis rs7914558 0.966 rs10786721 chr10:104654383 C/A cg15744005 chr10:104629667 AS3MT -0.41 -9.29 -0.45 1.79e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7412746 0.622 rs11552229 chr1:150783985 T/C cg18016565 chr1:150552671 MCL1 0.52 9.8 0.47 3.84e-20 Melanoma; LIHC cis rs929354 0.772 rs6459741 chr7:157014553 G/T cg16102536 chr7:156981717 UBE3C 0.36 6.14 0.32 2.25e-9 Body mass index; LIHC cis rs7647973 0.710 rs6446284 chr3:49616997 A/G cg03060546 chr3:49711283 APEH 0.62 6.96 0.35 1.76e-11 Menarche (age at onset); LIHC cis rs3008870 1.000 rs11208976 chr1:67434411 A/G cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs1371867 0.875 rs1660319 chr8:101337530 A/G cg06636551 chr8:101224915 SPAG1 -0.47 -8.38 -0.41 1.35e-15 Atrioventricular conduction; LIHC cis rs1892700 0.764 rs62227704 chr21:34910056 G/C cg14850771 chr21:34775459 IFNGR2 -0.45 -5.96 -0.31 6.41e-9 Educational attainment; LIHC cis rs1401999 1.000 rs7620350 chr3:183710053 A/T cg01324343 chr3:183735012 ABCC5 0.76 13.0 0.58 1.09e-31 Anterior chamber depth; LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg07308232 chr7:1071921 C7orf50 -0.4 -6.36 -0.33 6.3e-10 Longevity;Endometriosis; LIHC cis rs4319547 0.698 rs10773178 chr12:122944752 T/C cg05707623 chr12:122985044 ZCCHC8 -0.59 -8.03 -0.4 1.57e-14 Body mass index; LIHC cis rs35110281 0.659 rs2236667 chr21:45112939 A/G cg04455712 chr21:45112962 RRP1B 0.56 9.76 0.47 5.34e-20 Mean corpuscular volume; LIHC cis rs473651 1.000 rs473651 chr2:239335401 A/C cg21699342 chr2:239360505 ASB1 0.34 6.6 0.34 1.56e-10 Multiple system atrophy; LIHC cis rs35110281 0.805 rs4818843 chr21:45006607 C/T cg01579765 chr21:45077557 HSF2BP -0.36 -6.76 -0.34 6.06e-11 Mean corpuscular volume; LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.57 0.62 9.41e-38 Prudent dietary pattern; LIHC cis rs6570726 0.791 rs11155432 chr6:145898761 T/C cg13319975 chr6:146136371 FBXO30 -0.4 -6.38 -0.33 5.85e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6516091 0.640 rs6117070 chr20:6061606 A/G cg25325723 chr20:6104886 FERMT1 -0.56 -5.8 -0.3 1.5e-8 Abdominal aortic aneurysm; LIHC trans rs8073060 0.544 rs8071584 chr17:33999435 G/A cg19694781 chr19:47549865 TMEM160 -1.22 -12.48 -0.56 1.02e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2354432 0.546 rs11240030 chr1:146882616 G/A cg25205988 chr1:146714368 CHD1L 0.88 12.17 0.55 1.44e-28 Mitochondrial DNA levels; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg02951883 chr7:2050386 MAD1L1 -0.53 -7.94 -0.39 2.86e-14 Bipolar disorder and schizophrenia; LIHC cis rs1580019 0.520 rs13228793 chr7:32711465 C/T cg07520158 chr7:32535189 LSM5;AVL9 0.49 6.37 0.33 6.03e-10 Cognitive ability; LIHC cis rs12497850 0.644 rs11928552 chr3:48739883 T/C cg06212747 chr3:49208901 KLHDC8B 0.5 6.39 0.33 5.43e-10 Parkinson's disease; LIHC cis rs969413 0.624 rs9914093 chr17:79260653 C/G cg08034816 chr17:79219380 SLC38A10 0.42 6.85 0.35 3.34e-11 Frontotemporal dementia; LIHC cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg26939375 chr7:64535504 NA -0.44 -6.66 -0.34 1.07e-10 Aortic root size; LIHC cis rs6430585 0.528 rs75524146 chr2:136725459 C/T cg07169764 chr2:136633963 MCM6 1.28 21.09 0.75 7.5e-64 Corneal structure; LIHC cis rs11711311 1.000 rs7645473 chr3:113516187 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -7.08 -0.36 8.48e-12 IgG glycosylation; LIHC cis rs6542838 0.611 rs1976766 chr2:99522754 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.87 -0.35 3.1e-11 Fear of minor pain; LIHC cis rs7614311 0.555 rs58676857 chr3:63903883 G/A cg22134162 chr3:63841271 THOC7 -0.5 -6.09 -0.31 3.09e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs11792861 0.888 rs72607168 chr9:111832192 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.82 0.43 6.02e-17 Menarche (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00014996 chr18:158348 USP14 -0.43 -6.35 -0.32 6.8e-10 Longevity; LIHC cis rs7615952 0.866 rs13063119 chr3:125643847 G/A cg05084668 chr3:125655381 ALG1L -0.58 -8.23 -0.41 3.94e-15 Blood pressure (smoking interaction); LIHC cis rs2066819 1.000 rs2629447 chr12:56700809 G/A cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Psoriasis vulgaris; LIHC cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg07061783 chr6:25882402 NA -0.48 -6.69 -0.34 9.05e-11 Blood metabolite levels; LIHC cis rs2836974 0.545 rs8128901 chr21:40710419 G/A cg11890956 chr21:40555474 PSMG1 0.57 8.48 0.42 6.76e-16 Cognitive function; LIHC cis rs7568458 0.684 rs1048739 chr2:85764968 T/G cg02493740 chr2:85810744 VAMP5 -0.47 -7.84 -0.39 5.6e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9814567 1.000 rs7630874 chr3:134293291 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.14 0.32 2.3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg06481639 chr22:41940642 POLR3H -0.67 -7.04 -0.36 1.07e-11 Vitiligo; LIHC cis rs6424115 1.000 rs7514394 chr1:24100223 A/G cg15997130 chr1:24165203 NA -0.4 -8.27 -0.41 3.1e-15 Immature fraction of reticulocytes; LIHC cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.26 0.45 2.33e-18 Bipolar disorder; LIHC cis rs2580764 0.540 rs10174838 chr2:55241216 A/T cg09592903 chr2:55203963 RTN4 -0.7 -12.84 -0.57 4.62e-31 Mean platelet volume; LIHC cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg00684032 chr4:1343700 KIAA1530 -0.35 -5.83 -0.3 1.31e-8 Obesity-related traits; LIHC cis rs7100689 0.646 rs2039757 chr10:82078868 C/A cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs7772486 0.720 rs7752286 chr6:146072662 C/T cg13319975 chr6:146136371 FBXO30 0.4 6.61 0.34 1.46e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs12701220 0.655 rs7778968 chr7:1144622 C/G cg09177884 chr7:1199841 ZFAND2A -0.53 -6.21 -0.32 1.51e-9 Bronchopulmonary dysplasia; LIHC cis rs6500602 0.702 rs11076835 chr16:4549618 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.52 8.39 0.41 1.34e-15 Schizophrenia; LIHC trans rs11098499 0.954 rs6846442 chr4:120326323 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs2637266 1.000 rs12774835 chr10:78352226 C/G cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg05590025 chr7:65112418 INTS4L2 0.65 7.4 0.37 1.07e-12 Diabetic kidney disease; LIHC cis rs763121 0.853 rs138705 chr22:39133803 C/T cg14440974 chr22:39074834 NA -0.39 -6.41 -0.33 4.91e-10 Menopause (age at onset); LIHC cis rs9790314 0.663 rs6804650 chr3:160648953 A/G cg03342759 chr3:160939853 NMD3 -0.58 -7.12 -0.36 6.32e-12 Morning vs. evening chronotype; LIHC cis rs11971779 0.680 rs4732376 chr7:139098024 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg09260627 chr8:8243751 NA -0.51 -6.5 -0.33 2.93e-10 Monocyte count; LIHC cis rs9733 0.519 rs11204717 chr1:150709129 T/A cg18016565 chr1:150552671 MCL1 0.59 11.39 0.52 1.03e-25 Tonsillectomy; LIHC cis rs10791097 0.694 rs10791100 chr11:130738946 T/A cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1003719 0.715 rs13046581 chr21:38551985 G/T cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.78 -0.5 1.62e-23 Eye color traits; LIHC cis rs17102423 0.589 rs8011585 chr14:65522223 T/A cg16583315 chr14:65563665 MAX -0.37 -7.22 -0.36 3.39e-12 Obesity-related traits; LIHC cis rs875971 0.862 rs28470208 chr7:65584700 A/G cg18252515 chr7:66147081 NA 0.42 5.79 0.3 1.61e-8 Aortic root size; LIHC cis rs7587476 0.736 rs62202002 chr2:215690600 T/C cg04530015 chr2:215796436 ABCA12 -0.39 -6.36 -0.33 6.61e-10 Neuroblastoma; LIHC cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg02187348 chr16:89574699 SPG7 0.65 10.11 0.48 3.29e-21 Multiple myeloma (IgH translocation); LIHC cis rs765787 0.530 rs1706835 chr15:45517884 G/A cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.74 -0.3 2.1e-8 Uric acid levels; LIHC cis rs317689 0.819 rs317685 chr12:69715457 A/G cg19645103 chr12:69753606 YEATS4 0.46 6.3 0.32 9.07e-10 Response to diuretic therapy; LIHC cis rs4755351 0.553 rs10836023 chr11:33125046 G/A cg05567920 chr11:33183001 CSTF3 0.42 6.17 0.32 1.96e-9 Lung cancer in ever smokers; LIHC cis rs11864453 0.786 rs1050362 chr16:72130815 C/A cg01557791 chr16:72042693 DHODH -0.53 -8.56 -0.42 4.01e-16 Fibrinogen levels; LIHC cis rs8062405 1.000 rs11861174 chr16:28871989 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs4596713 0.538 rs10125494 chr9:71770861 C/G cg16512924 chr15:28394682 HERC2 0.4 6.47 0.33 3.43e-10 Headache; LIHC cis rs10463316 0.963 rs4958450 chr5:150739932 A/C cg03212797 chr5:150827313 SLC36A1 -0.41 -6.21 -0.32 1.53e-9 Metabolite levels (Pyroglutamine); LIHC cis rs2439831 1.000 rs689754 chr15:43775895 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.4 0.59 3.47e-33 Lung cancer in ever smokers; LIHC cis rs12220238 1.000 rs11000909 chr10:75944828 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.72 6.92 0.35 2.24e-11 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs1974653 0.781 rs175164 chr22:20115562 C/T cg20152630 chr19:46405944 MYPOP 0.47 6.07 0.31 3.37e-9 Schizophrenia; LIHC cis rs12908161 1.000 rs12911736 chr15:85240008 A/G cg17507749 chr15:85114479 UBE2QP1 0.66 7.57 0.38 3.6e-13 Schizophrenia; LIHC cis rs17106184 1.000 rs1573012 chr1:51369991 T/C cg07174182 chr1:51127561 FAF1 -0.75 -7.61 -0.38 2.74e-13 Type 2 diabetes; LIHC cis rs780096 0.526 rs7602534 chr2:27592423 C/T cg21747090 chr2:27597821 SNX17 -0.43 -6.36 -0.33 6.62e-10 Total body bone mineral density; LIHC cis rs72949976 1.000 rs62186569 chr2:214034151 C/T cg08319019 chr2:214017104 IKZF2 -0.61 -6.59 -0.34 1.64e-10 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs2991971 0.776 rs12139364 chr1:45890155 T/C cg15605315 chr1:45957053 TESK2 0.49 6.93 0.35 2.12e-11 High light scatter reticulocyte count; LIHC cis rs1005277 0.579 rs1780130 chr10:38485378 T/A cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.25 -0.32 1.21e-9 Extrinsic epigenetic age acceleration; LIHC cis rs13108904 0.934 rs35201724 chr4:1310717 C/G cg00684032 chr4:1343700 KIAA1530 0.52 7.48 0.37 6.3e-13 Obesity-related traits; LIHC cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg22633049 chr21:46681294 NA -0.37 -6.34 -0.32 7.08e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7095607 0.538 rs2255136 chr10:69921733 T/A cg18986048 chr10:69913749 MYPN 0.47 7.06 0.36 9.14e-12 Lung function (FVC); LIHC cis rs7659604 0.676 rs4516739 chr4:122699741 G/T cg20573242 chr4:122745356 CCNA2 0.51 7.39 0.37 1.13e-12 Type 2 diabetes; LIHC cis rs703842 1.000 rs11172343 chr12:58188157 T/C cg18357645 chr12:58087776 OS9 -0.45 -6.98 -0.35 1.49e-11 Multiple sclerosis; LIHC cis rs67311347 0.955 rs6773383 chr3:40377412 A/T cg13409248 chr3:40428643 ENTPD3 0.4 6.61 0.34 1.51e-10 Renal cell carcinoma; LIHC cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg02290350 chr8:58132656 NA 0.41 8.63 0.42 2.39e-16 Developmental language disorder (linguistic errors); LIHC cis rs1866706 1.000 rs2165283 chr11:12873035 G/A cg25843174 chr11:12811716 TEAD1 -0.32 -6.75 -0.34 6.5e-11 Intelligence (multi-trait analysis); LIHC cis rs506338 0.517 rs471618 chr11:64465403 T/C cg27209729 chr11:64428925 NRXN2 0.35 6.49 0.33 3.07e-10 Body mass index;Urate levels; LIHC cis rs12824058 0.737 rs11060829 chr12:130814996 G/T cg24838063 chr12:130822603 PIWIL1 0.67 9.97 0.47 9.99e-21 Menopause (age at onset); LIHC cis rs55823223 0.564 rs9894009 chr17:73850414 C/T cg08125733 chr17:73851984 WBP2 0.85 12.45 0.56 1.31e-29 Psoriasis; LIHC cis rs2071426 1.000 rs2071426 chr10:96828323 T/C cg09036531 chr10:96991505 NA -0.49 -5.9 -0.3 8.78e-9 Blood metabolite levels; LIHC cis rs2274273 0.870 rs7160523 chr14:55594560 G/T cg01864836 chr14:55583639 NA -0.42 -8.08 -0.4 1.15e-14 Protein biomarker; LIHC cis rs4674676 1 rs4674676 chr2:223529112 A/G cg25565276 chr2:223520875 FARSB 1.0 14.38 0.61 5.37e-37 Chin dimples; LIHC cis rs11098499 1.000 rs1011054 chr4:120202387 A/G cg09307838 chr4:120376055 NA -0.77 -11.42 -0.53 8.38e-26 Corneal astigmatism; LIHC cis rs798554 0.757 rs2533882 chr7:2846894 G/T cg19717773 chr7:2847554 GNA12 -0.43 -6.66 -0.34 1.09e-10 Height; LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg10217327 chr6:118973057 C6orf204 0.68 6.93 0.35 2.12e-11 Diastolic blood pressure; LIHC cis rs8062405 0.723 rs113208333 chr16:28606160 G/T cg07451762 chr16:28383216 NA 0.42 7.5 0.38 5.55e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs832187 0.603 rs7615475 chr3:63926661 C/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.45 -6.37 -0.33 6.13e-10 Schizophrenia; LIHC cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.91 0.7 4.35e-51 Mean corpuscular hemoglobin; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg02990361 chr1:107599529 PRMT6 -0.67 -11.2 -0.52 5.26e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6748734 1.000 rs4344931 chr2:241818527 A/C cg20140201 chr2:241835670 C2orf54 -0.46 -6.24 -0.32 1.31e-9 Urinary metabolites; LIHC cis rs9394841 0.667 rs9471667 chr6:41776681 T/C cg17623882 chr6:41773611 USP49 -0.43 -5.8 -0.3 1.52e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs2073499 0.872 rs2282751 chr3:50291785 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.79 -12.16 -0.55 1.68e-28 Schizophrenia; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg07810114 chr1:12018622 PLOD1 -0.49 -6.32 -0.32 8.37e-10 Alcohol dependence; LIHC cis rs600806 0.815 rs10858089 chr1:109926828 T/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs8084351 0.577 rs4426414 chr18:50621741 G/C cg24270629 chr18:50823537 DCC 0.44 6.65 0.34 1.15e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs57244997 0.725 rs58957516 chr6:162427889 C/A cg17173639 chr6:162384350 PARK2 -0.5 -6.31 -0.32 8.79e-10 Mosquito bite size; LIHC cis rs10733682 0.659 rs13287548 chr9:129466456 C/T cg00232160 chr9:129468157 NA 0.37 6.41 0.33 4.89e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8067545 0.611 rs2526476 chr17:20134289 C/T cg13482628 chr17:19912719 NA -0.43 -7.04 -0.36 1.09e-11 Schizophrenia; LIHC cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg09455208 chr3:40491958 NA 0.36 7.2 0.36 3.91e-12 Renal cell carcinoma; LIHC cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg10360323 chr17:41437877 NA 0.4 5.97 0.31 5.87e-9 Menopause (age at onset); LIHC cis rs1144333 1.000 rs78223982 chr1:76465203 T/C cg10523679 chr1:76189770 ACADM 0.42 5.97 0.31 6.09e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs477692 0.792 rs12762024 chr10:131441055 G/C cg05714579 chr10:131428358 MGMT -0.48 -7.75 -0.39 1.08e-13 Response to temozolomide; LIHC cis rs1003719 0.667 rs28666643 chr21:38455999 T/G cg10648535 chr21:38446584 PIGP;TTC3 0.56 6.49 0.33 2.99e-10 Eye color traits; LIHC cis rs10504229 0.906 rs2270608 chr8:58194688 T/C cg02290350 chr8:58132656 NA 0.44 8.72 0.43 1.21e-16 Developmental language disorder (linguistic errors); LIHC cis rs6964587 0.967 rs17164315 chr7:91659150 C/G cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC cis rs9858213 1 rs9858213 chr3:49731861 G/T cg03060546 chr3:49711283 APEH -0.64 -8.64 -0.42 2.19e-16 Educational attainment; LIHC cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg27572855 chr1:25598939 RHD 0.41 8.88 0.43 3.86e-17 Erythrocyte sedimentation rate; LIHC cis rs4631830 0.720 rs2125770 chr10:51514824 T/C cg20129853 chr10:51489980 NA -0.4 -8.76 -0.43 8.94e-17 Prostate-specific antigen levels; LIHC cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg27170947 chr2:26402098 FAM59B 0.67 8.3 0.41 2.37e-15 Gut microbiome composition (summer); LIHC cis rs2439831 0.850 rs28578398 chr15:44075046 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.43 0.33 4.32e-10 Lung cancer in ever smokers; LIHC cis rs4742903 0.935 rs1507513 chr9:106973857 A/G cg14250997 chr9:106856677 SMC2 0.34 5.76 0.3 1.88e-8 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1577917 0.654 rs9450284 chr6:86199329 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.44 7.94 0.39 2.98e-14 Response to antipsychotic treatment; LIHC cis rs13118159 0.801 rs1128427 chr4:1330759 T/C cg02969873 chr4:1330999 MAEA -0.41 -6.25 -0.32 1.22e-9 Longevity; LIHC cis rs12497850 0.805 rs11130176 chr3:48844077 A/G cg06212747 chr3:49208901 KLHDC8B 0.55 7.12 0.36 6.57e-12 Parkinson's disease; LIHC cis rs4713118 0.869 rs6922574 chr6:27693003 A/T cg20933634 chr6:27740509 NA 0.47 6.24 0.32 1.28e-9 Parkinson's disease; LIHC cis rs7131987 0.934 rs7316004 chr12:29411698 C/T cg12903224 chr12:29470962 FAR2 -0.37 -5.91 -0.3 8.31e-9 QT interval; LIHC trans rs208520 0.661 rs207090 chr6:66783963 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -8.98 -0.44 1.84e-17 Exhaled nitric oxide output; LIHC cis rs4728302 0.934 rs2971963 chr7:133641505 A/G cg10665199 chr7:133106180 EXOC4 -0.35 -5.84 -0.3 1.21e-8 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs2303745 0.589 rs7246262 chr19:17392483 C/G cg02221750 chr19:17393354 ANKLE1 -0.42 -6.01 -0.31 4.69e-9 Systemic lupus erythematosus; LIHC cis rs801193 1.000 rs7788576 chr7:66148302 G/A cg18876405 chr7:65276391 NA -0.43 -7.36 -0.37 1.34e-12 Aortic root size; LIHC cis rs1878931 0.580 rs7194596 chr16:3404408 T/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.78 12.4 0.56 1.98e-29 Body mass index (adult); LIHC cis rs853679 0.542 rs6934769 chr6:28090931 A/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs7193541 0.929 rs12933037 chr16:74660174 G/A cg01733217 chr16:74700730 RFWD3 0.55 10.34 0.49 5.68e-22 Multiple myeloma; LIHC trans rs4906332 1.000 rs35126287 chr14:103959432 A/G cg17675199 chr6:35436792 RPL10A 0.35 6.89 0.35 2.76e-11 Coronary artery disease; LIHC cis rs9915021 0.623 rs9899860 chr17:33941120 C/T cg20932281 chr17:33905541 PEX12 0.57 7.06 0.36 9.29e-12 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs7917772 0.545 rs3934960 chr10:104355275 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.73 -0.39 1.23e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs67311347 0.577 rs1880763 chr3:40283255 C/T cg10755058 chr3:40428713 ENTPD3 -0.36 -5.92 -0.3 8.04e-9 Renal cell carcinoma; LIHC cis rs6964587 0.626 rs1011372 chr7:91509867 T/C cg17063962 chr7:91808500 NA -0.61 -11.04 -0.51 1.96e-24 Breast cancer; LIHC cis rs1577917 0.958 rs36042496 chr6:86524214 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27596707 chr10:65029168 JMJD1C -0.36 -6.11 -0.31 2.78e-9 Cognitive function; LIHC cis rs3770081 1.000 rs76081054 chr2:86285037 T/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.96 -11.41 -0.53 9.09e-26 Facial emotion recognition (sad faces); LIHC cis rs9457247 1.000 rs408087 chr6:167398952 C/T cg23791538 chr6:167370224 RNASET2 -0.64 -10.96 -0.51 3.81e-24 Crohn's disease; LIHC trans rs1814175 0.817 rs1818890 chr11:49856882 T/C cg03929089 chr4:120376271 NA -0.9 -18.64 -0.71 5.02e-54 Height; LIHC cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.05e-17 Bipolar disorder; LIHC cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg26531700 chr6:26746687 NA 0.38 6.44 0.33 3.94e-10 Intelligence (multi-trait analysis); LIHC cis rs853679 0.517 rs9380047 chr6:28037893 G/T cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs10744422 1.000 rs897385 chr12:123341297 A/G cg07706471 chr12:123319906 HIP1R -0.63 -8.28 -0.41 2.88e-15 Schizophrenia; LIHC trans rs208520 0.874 rs208473 chr6:66917265 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.7 -7.79 -0.39 8.3e-14 Exhaled nitric oxide output; LIHC cis rs3768617 0.510 rs10752896 chr1:183068516 A/C ch.1.3577855R chr1:183094577 LAMC1 0.62 10.81 0.5 1.29e-23 Fuchs's corneal dystrophy; LIHC cis rs7258465 1.000 rs10411009 chr19:18606266 A/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.38 -0.37 1.24e-12 Breast cancer; LIHC cis rs3892630 0.588 rs7260037 chr19:33242701 G/A cg22980127 chr19:33182716 NUDT19 1.06 13.86 0.6 5.48e-35 Red blood cell traits; LIHC cis rs950169 0.800 rs4099846 chr15:84956894 C/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.5 0.42 5.84e-16 Schizophrenia; LIHC cis rs10849893 0.538 rs10744762 chr12:121839701 A/C cg01154721 chr12:121881891 KDM2B 0.36 5.99 0.31 5.46e-9 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs12477438 0.798 rs2309524 chr2:99659510 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.58 -0.5 7.78e-23 Chronic sinus infection; LIHC cis rs10911232 0.507 rs6660111 chr1:183014289 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.1e-22 Hypertriglyceridemia; LIHC cis rs35110281 0.776 rs9306159 chr21:45061839 G/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.56 -0.33 2.01e-10 Mean corpuscular volume; LIHC cis rs7666738 0.830 rs28867087 chr4:98880349 T/A cg05340658 chr4:99064831 C4orf37 0.67 12.33 0.55 3.73e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs1005277 0.505 rs7917943 chr10:38195811 T/A cg00409905 chr10:38381863 ZNF37A 0.56 9.53 0.46 3.1e-19 Extrinsic epigenetic age acceleration; LIHC cis rs1801251 1.000 rs71421663 chr2:233619131 A/G cg08000102 chr2:233561755 GIGYF2 0.77 11.53 0.53 3.25e-26 Coronary artery disease; LIHC cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.03 -11.63 -0.53 1.45e-26 Platelet count; LIHC cis rs9640161 0.742 rs2108851 chr7:150019634 T/C cg10018233 chr7:150070692 REPIN1 0.56 9.53 0.46 2.96e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs17384381 1.000 rs12135333 chr1:85890494 C/A cg16011679 chr1:85725395 C1orf52 0.8 8.45 0.42 8.66e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs12976411 1.000 rs12976411 chr19:32882020 A/T cg02282382 chr19:32836354 ZNF507 -0.47 -5.79 -0.3 1.6e-8 Coronary artery disease; LIHC cis rs2243480 1.000 rs2707831 chr7:66062511 G/A cg18252515 chr7:66147081 NA -1.33 -18.21 -0.7 2.75e-52 Diabetic kidney disease; LIHC cis rs7399018 0.739 rs6580811 chr12:51612501 T/C cg25754956 chr12:51612065 POU6F1 0.79 9.36 0.45 1.06e-18 Cisplatin-induced ototoxicity; LIHC cis rs13191362 0.872 rs13196631 chr6:163001588 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7078219 0.523 rs4129134 chr10:101284345 C/G cg06854084 chr10:101292507 NKX2-3 -0.33 -6.0 -0.31 5.16e-9 Dental caries; LIHC cis rs13272623 0.502 rs268627 chr8:71561041 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.45 -5.99 -0.31 5.34e-9 IgG glycosylation; LIHC cis rs7762018 0.943 rs7772889 chr6:170142458 T/C cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.69 0.34 8.87e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs17106184 0.551 rs11205718 chr1:50854466 C/T cg07174182 chr1:51127561 FAF1 -0.44 -5.73 -0.3 2.19e-8 Type 2 diabetes; LIHC cis rs8072100 0.840 rs9912311 chr17:45547132 T/C cg08085267 chr17:45401833 C17orf57 -0.55 -8.23 -0.41 3.95e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg11941060 chr3:133502564 NA -0.4 -5.94 -0.31 6.94e-9 Iron status biomarkers; LIHC cis rs34779708 0.733 rs12254018 chr10:35550641 T/A cg03585969 chr10:35415529 CREM 0.74 10.66 0.5 4.27e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs546131 0.928 rs535719 chr11:34853382 A/G cg11058730 chr11:34937778 PDHX;APIP 0.63 9.66 0.46 1.14e-19 Lung disease severity in cystic fibrosis; LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg22442454 chr1:209979470 IRF6 0.39 6.3 0.32 9.1e-10 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC cis rs6714710 0.603 rs17489454 chr2:98407350 C/T cg26665480 chr2:98280029 ACTR1B 0.46 6.58 0.34 1.72e-10 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs5770917 1.000 rs17848459 chr22:51012311 G/T cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.48 -5.91 -0.3 8.28e-9 Narcolepsy; LIHC cis rs826838 0.967 rs11183022 chr12:38652519 G/A cg26384229 chr12:38710491 ALG10B 1.08 14.69 0.62 3.18e-38 Heart rate; LIHC cis rs9811920 0.638 rs796978 chr3:99564321 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 7.14 0.36 5.65e-12 Axial length; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05464589 chr10:134571599 INPP5A 0.45 6.04 0.31 3.91e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10193935 0.892 rs7574609 chr2:42388468 C/A cg27598129 chr2:42591480 NA -0.73 -11.36 -0.52 1.41e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs6733011 0.508 rs925887 chr2:99514671 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.48 6.82 0.35 4.17e-11 Bipolar disorder; LIHC cis rs9309473 1.000 rs60844734 chr2:73623205 T/A cg20560298 chr2:73613845 ALMS1 -0.59 -6.87 -0.35 3.07e-11 Metabolite levels; LIHC trans rs61041384 0.661 rs4759411 chr12:123740843 C/G cg07919128 chr17:18022025 MYO15A 0.68 6.77 0.34 5.61e-11 Schizophrenia; LIHC trans rs1499614 0.831 rs3800822 chr7:66147149 A/G cg10756647 chr7:56101905 PSPH -0.98 -11.62 -0.53 1.57e-26 Gout; LIHC cis rs1865721 0.771 rs72975985 chr18:73127648 C/T cg26385618 chr18:73139727 C18orf62 -0.32 -8.5 -0.42 6.16e-16 Intelligence; LIHC trans rs2235573 0.527 rs5756853 chr22:38329524 G/A cg19894588 chr14:64061835 NA -0.5 -6.49 -0.33 3.06e-10 Glioblastoma;Glioma; LIHC cis rs35306767 0.903 rs11253467 chr10:901244 A/G cg20503657 chr10:835505 NA 1.03 11.72 0.54 6.64e-27 Eosinophil percentage of granulocytes; LIHC cis rs7395581 0.918 rs7120957 chr11:47340649 A/G cg25783544 chr11:47291846 MADD 0.41 5.95 0.31 6.8e-9 HDL cholesterol; LIHC cis rs896854 0.517 rs1011795 chr8:95951073 G/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.37 -0.37 1.27e-12 Type 2 diabetes; LIHC cis rs9814567 1.000 rs7429866 chr3:134236306 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs589448 0.902 rs315134 chr12:69762713 G/A cg22834771 chr12:69754056 YEATS4 -0.55 -9.98 -0.47 9.68e-21 Cerebrospinal fluid biomarker levels; LIHC cis rs8017423 0.935 rs59179255 chr14:90691773 A/C cg14092571 chr14:90743983 NA -0.37 -5.79 -0.3 1.59e-8 Mortality in heart failure; LIHC cis rs11125080 0.735 rs11682326 chr2:46734550 A/G cg02822958 chr2:46747628 ATP6V1E2 -0.55 -5.9 -0.3 8.84e-9 Anti-saccade response;Anti-saccade error rate in psychotic disorders; LIHC cis rs10791097 0.702 rs11222346 chr11:130715343 T/C cg12179176 chr11:130786555 SNX19 -0.61 -9.21 -0.45 3.3e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9393692 0.905 rs2393592 chr6:26285560 A/G cg00631329 chr6:26305371 NA -0.44 -7.28 -0.37 2.31e-12 Educational attainment; LIHC cis rs1559088 0.545 rs7257431 chr19:33566924 A/G cg27124370 chr19:33622961 WDR88 0.57 8.24 0.41 3.71e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg13607699 chr17:42295918 UBTF 0.58 10.67 0.5 4.02e-23 Total body bone mineral density; LIHC cis rs2573652 0.722 rs8041337 chr15:100541808 T/C cg09918751 chr15:100517450 ADAMTS17 -0.7 -12.39 -0.56 2.23e-29 Height; LIHC cis rs1005277 0.579 rs1780133 chr10:38499509 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg14004847 chr7:1930337 MAD1L1 -0.46 -6.78 -0.34 5.32e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs17253792 0.822 rs10143002 chr14:56074278 G/A cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs400736 0.702 rs225134 chr1:8098730 A/G cg25007680 chr1:8021821 PARK7 0.63 9.77 0.47 4.77e-20 Response to antidepressants and depression; LIHC cis rs6940638 0.531 rs12211984 chr6:26986054 G/C cg12292205 chr6:26970375 C6orf41 0.45 7.76 0.39 1.02e-13 Intelligence (multi-trait analysis); LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg14893161 chr1:205819251 PM20D1 0.68 9.89 0.47 1.95e-20 Menarche (age at onset); LIHC trans rs6951245 0.554 rs78999139 chr7:1138525 G/A cg13565492 chr6:43139072 SRF -0.79 -7.32 -0.37 1.81e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs899997 1.000 rs11072794 chr15:79006582 A/G cg04896959 chr15:78267971 NA 0.4 7.93 0.39 3.11e-14 Coronary artery disease or large artery stroke; LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs10845606 0.581 rs10772591 chr12:12834802 A/G cg04607235 chr12:12878440 APOLD1 -0.44 -6.18 -0.32 1.85e-9 Systemic lupus erythematosus; LIHC cis rs172166 0.694 rs203877 chr6:28048624 T/C cg25329415 chr6:28076851 NA 0.27 5.75 0.3 1.97e-8 Cardiac Troponin-T levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17019285 chr8:11725104 CTSB 0.51 6.94 0.35 2e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs2455799 0.613 rs6772879 chr3:15741793 G/A cg12698662 chr3:15914712 MIR563 -0.35 -6.52 -0.33 2.6e-10 Mean platelet volume; LIHC cis rs6430585 0.583 rs2322813 chr2:136582809 A/G cg07169764 chr2:136633963 MCM6 1.33 20.23 0.74 2.12e-60 Corneal structure; LIHC cis rs10540 1.000 rs35811812 chr11:498442 G/A cg03352830 chr11:487213 PTDSS2 0.8 6.84 0.35 3.69e-11 Body mass index; LIHC cis rs6963495 0.818 rs55922564 chr7:105155890 G/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22433398 chr13:27825486 RPL21;RPL21P28 0.51 7.46 0.37 7.19e-13 Lung function (FEV1/FVC); LIHC cis rs1712517 0.904 rs10883863 chr10:105161879 G/A cg05636881 chr10:105038444 INA -0.41 -6.32 -0.32 8.11e-10 Migraine; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08077726 chr17:74734280 SFRS2;MFSD11 0.51 7.61 0.38 2.64e-13 Pancreatic cancer; LIHC cis rs2380220 0.574 rs9400526 chr6:95998441 T/C cg15832292 chr6:96025679 MANEA 0.58 7.78 0.39 8.73e-14 Behavioural disinhibition (generation interaction); LIHC cis rs10791097 0.694 rs10791100 chr11:130738946 T/A cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2072499 1.000 rs2241107 chr1:156182710 C/T cg24450063 chr1:156163899 SLC25A44 -1.05 -19.07 -0.72 9.87e-56 Testicular germ cell tumor; LIHC cis rs763121 0.853 rs138704 chr22:39133410 A/G cg06544989 chr22:39130855 UNC84B 0.38 6.17 0.32 1.96e-9 Menopause (age at onset); LIHC trans rs6598955 0.671 rs59143843 chr1:26641595 G/T cg07461501 chr17:79650226 HGS;ARL16 -0.76 -7.8 -0.39 7.42e-14 Obesity-related traits; LIHC cis rs9790314 0.586 rs67077657 chr3:161138521 A/G cg17135325 chr3:160939158 NMD3 0.49 7.23 0.36 3.19e-12 Morning vs. evening chronotype; LIHC cis rs208520 1.000 rs9453663 chr6:66976077 A/G cg07460842 chr6:66804631 NA 0.68 7.23 0.36 3.16e-12 Exhaled nitric oxide output; LIHC cis rs7208859 0.623 rs55811708 chr17:29104731 G/T cg14067834 chr17:29058358 SUZ12P 0.69 6.81 0.35 4.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7223966 1.000 rs13380863 chr17:61780793 G/A cg05941027 chr17:61774174 LIMD2 0.34 6.8 0.35 4.73e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2153535 0.601 rs9505474 chr6:8539794 C/G cg21535247 chr6:8435926 SLC35B3 0.64 8.33 0.41 2.02e-15 Motion sickness; LIHC cis rs7903847 0.692 rs7900255 chr10:99157575 G/A cg08345082 chr10:99160200 RRP12 -0.4 -6.71 -0.34 8.13e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs785830 0.636 rs601023 chr9:224693 A/G cg14500300 chr9:211689 NA 0.28 5.93 0.31 7.39e-9 Platelet distribution width; LIHC cis rs9457247 1.000 rs408040 chr6:167398903 A/T cg23791538 chr6:167370224 RNASET2 -0.65 -11.25 -0.52 3.37e-25 Crohn's disease; LIHC cis rs7095944 0.614 rs10901818 chr10:126449428 G/A cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.5e-10 Asthma; LIHC cis rs7618501 0.699 rs11130224 chr3:49936910 T/A cg21467203 chr3:49911342 NA -0.48 -8.44 -0.42 9.04e-16 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.519 rs10880194 chr12:38302836 G/A cg26384229 chr12:38710491 ALG10B 0.6 8.21 0.41 4.57e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs12586317 0.586 rs74243591 chr14:35520917 C/T cg16230307 chr14:35515116 FAM177A1 0.82 13.6 0.59 5.75e-34 Psoriasis; LIHC trans rs916888 0.610 rs199529 chr17:44837217 A/C cg13957321 chr17:43675089 NA 0.44 7.15 0.36 5.18e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7613875 0.578 rs4688753 chr3:50074773 A/G cg05623727 chr3:50126028 RBM5 -0.34 -5.82 -0.3 1.38e-8 Body mass index; LIHC cis rs1403694 0.669 rs10440056 chr3:186433822 C/T cg12454167 chr3:186435060 KNG1 0.38 8.97 0.44 2.01e-17 Blood protein levels; LIHC cis rs12458462 0.812 rs34583578 chr18:77491070 C/T cg11879182 chr18:77439856 CTDP1 0.83 13.42 0.59 2.78e-33 Monocyte count; LIHC trans rs55986470 0.817 rs66895963 chr2:239403902 A/T cg01134436 chr17:81009848 B3GNTL1 0.59 6.1 0.31 2.93e-9 Chronotype; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02641675 chr6:74363634 SLC17A5 -0.38 -6.17 -0.32 1.88e-9 Immature fraction of reticulocytes; LIHC cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg06238570 chr21:40685208 BRWD1 0.6 7.24 0.36 3.01e-12 Cognitive function; LIHC cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg08048268 chr3:133502702 NA -0.43 -6.5 -0.33 2.82e-10 Iron status biomarkers; LIHC cis rs2112347 0.502 rs34342 chr5:74934213 A/C cg08253296 chr5:74907592 NA -0.47 -6.01 -0.31 4.67e-9 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs709400 0.859 rs7154948 chr14:104022944 C/T cg26031613 chr14:104095156 KLC1 1.13 14.64 0.62 5.12e-38 Body mass index; LIHC cis rs80282103 0.571 rs56183119 chr10:1068370 C/T cg08668510 chr10:1095578 IDI1 0.71 7.42 0.37 9.12e-13 Glomerular filtration rate (creatinine); LIHC cis rs3820068 0.608 rs11544523 chr1:15904318 C/T cg17385448 chr1:15911702 AGMAT 0.38 6.13 0.31 2.4e-9 Systolic blood pressure; LIHC cis rs7959452 0.590 rs56054057 chr12:69775972 C/T cg20891283 chr12:69753455 YEATS4 0.89 19.41 0.72 4.15e-57 Blood protein levels; LIHC cis rs6466055 0.777 rs3801278 chr7:104907017 C/T cg04380332 chr7:105027541 SRPK2 0.36 6.71 0.34 8.15e-11 Schizophrenia; LIHC cis rs1577917 1.000 rs12201741 chr6:86602619 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.51 -0.49 1.47e-22 Response to antipsychotic treatment; LIHC cis rs7208859 0.623 rs73269945 chr17:29108759 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7618501 1.000 rs2271960 chr3:49878078 A/G cg21467203 chr3:49911342 NA -0.41 -7.25 -0.36 2.86e-12 Intelligence (multi-trait analysis); LIHC cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg21970626 chr13:21893289 NA -0.37 -6.11 -0.31 2.76e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg01818776 chr8:25202910 DOCK5 0.5 6.27 0.32 1.09e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg10883421 chr6:151773342 RMND1;C6orf211 0.78 14.91 0.63 4.59e-39 Menarche (age at onset); LIHC cis rs11098499 0.644 rs34835603 chr4:120553428 C/T cg09307838 chr4:120376055 NA 0.67 10.22 0.48 1.39e-21 Corneal astigmatism; LIHC cis rs7224685 0.569 rs7221595 chr17:4007594 C/T cg09695851 chr17:3907499 NA -0.54 -6.21 -0.32 1.5e-9 Type 2 diabetes; LIHC cis rs2066819 0.892 rs17118431 chr12:56667100 A/G cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.92e-25 Psoriasis vulgaris; LIHC cis rs17428076 0.874 rs62182372 chr2:172684487 C/T cg13550731 chr2:172543902 DYNC1I2 0.38 6.21 0.32 1.55e-9 Myopia; LIHC cis rs734999 0.545 rs6684865 chr1:2546229 A/G cg20673091 chr1:2541236 MMEL1 -0.28 -6.05 -0.31 3.91e-9 Ulcerative colitis; LIHC cis rs9640161 0.783 rs1132261 chr7:150059987 G/A cg17279839 chr7:150038598 RARRES2 0.41 8.17 0.4 5.86e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs882732 0.576 rs3827893 chr14:95033671 A/T cg14866387 chr14:95027382 SERPINA4 -0.38 -6.34 -0.32 7.06e-10 Blood protein levels; LIHC cis rs8062405 0.691 rs11646653 chr16:28922149 C/T cg07451762 chr16:28383216 NA -0.33 -6.28 -0.32 1.03e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4517514 0.509 rs10765252 chr11:89875664 C/T cg05041596 chr11:89867385 NAALAD2 0.41 6.59 0.34 1.69e-10 Trans fatty acid levels; LIHC trans rs5756813 0.754 rs4820307 chr22:38175955 G/A cg19894588 chr14:64061835 NA -0.63 -8.76 -0.43 9.08e-17 Optic cup area;Vertical cup-disc ratio; LIHC cis rs10779751 0.770 rs12075896 chr1:11200350 C/A cg08854313 chr1:11322531 MTOR -0.77 -9.9 -0.47 1.79e-20 Body mass index; LIHC cis rs9296404 1 rs9296404 chr6:42925803 T/C cg21280719 chr6:42927975 GNMT -0.33 -7.36 -0.37 1.39e-12 Plasma homocysteine levels (post-methionine load test); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14797243 chr11:68671428 IGHMBP2;MRPL21 0.41 6.68 0.34 9.77e-11 Cognitive function; LIHC cis rs7131987 0.903 rs11050162 chr12:29420054 T/G cg14222432 chr12:29376421 FAR2 0.38 7.31 0.37 1.89e-12 QT interval; LIHC cis rs7408868 1.000 rs4809029 chr19:15273248 A/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC cis rs6499255 0.951 rs16958970 chr16:69627793 G/A cg15192750 chr16:69999425 NA 0.47 7.0 0.35 1.38e-11 IgE levels; LIHC cis rs17253792 0.822 rs112308750 chr14:56080073 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs765787 0.530 rs28815867 chr15:45526805 G/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.05e-13 Uric acid levels; LIHC cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg27297192 chr10:134578999 INPP5A 0.55 7.59 0.38 3.1400000000000003e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2455799 0.593 rs13085352 chr3:15914845 T/C cg12698662 chr3:15914712 MIR563 -0.4 -7.51 -0.38 5.11e-13 Mean platelet volume; LIHC cis rs9911578 0.967 rs12944948 chr17:56951474 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC trans rs7618501 0.633 rs3774733 chr3:50037123 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.57 0.46 2.3e-19 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs4949874 chr1:76161889 T/C cg03433033 chr1:76189801 ACADM 0.66 9.19 0.44 4.02e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9918079 0.580 rs13120905 chr4:15612288 A/T cg21123203 chr4:15471301 CC2D2A 0.45 7.23 0.36 3.24e-12 Obesity-related traits; LIHC cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg13770153 chr20:60521292 NA -0.62 -13.48 -0.59 1.63e-33 Obesity-related traits; LIHC cis rs712039 0.652 rs853197 chr17:35848716 T/C cg16670864 chr17:35848621 DUSP14 0.35 5.88 0.3 9.85e-9 Tuberculosis; LIHC cis rs6840360 1.000 rs6818667 chr4:152598698 T/C cg22705602 chr4:152727874 NA -0.31 -6.58 -0.34 1.8e-10 Intelligence (multi-trait analysis); LIHC cis rs1577917 1.000 rs6914463 chr6:86653415 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.71 -0.38 1.4e-13 Response to antipsychotic treatment; LIHC cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg09455208 chr3:40491958 NA 0.33 6.59 0.34 1.67e-10 Renal cell carcinoma; LIHC cis rs908922 0.676 rs10788842 chr1:152514588 A/T cg20991723 chr1:152506922 NA 0.53 9.23 0.45 2.89e-18 Hair morphology; LIHC cis rs2180341 1.000 rs9398838 chr6:127635285 C/T cg27446573 chr6:127587934 RNF146 1.03 16.06 0.66 1.17e-43 Breast cancer; LIHC cis rs72627509 0.629 rs1718824 chr4:57903747 A/C cg26694713 chr4:57773883 REST -0.44 -6.08 -0.31 3.15e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4906332 1.000 rs35366629 chr14:103903054 A/G cg19000871 chr14:103996768 TRMT61A -0.46 -7.86 -0.39 4.99e-14 Coronary artery disease; LIHC cis rs61774743 0.754 rs11581271 chr1:41835061 C/G cg08462924 chr1:41848221 NA 0.35 5.93 0.31 7.21e-9 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08122663 chr6:17706677 NUP153 0.37 6.04 0.31 3.92e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs61677309 1.000 rs4938501 chr11:118166497 A/G cg06090739 chr11:118230722 UBE4A 0.32 5.93 0.31 7.5e-9 Lung cancer in ever smokers; LIHC cis rs10744422 1.000 rs921808 chr12:123323135 A/G cg25930673 chr12:123319894 HIP1R 0.86 11.24 0.52 3.86e-25 Schizophrenia; LIHC cis rs9486719 0.947 rs72932805 chr6:96902933 T/G cg06623918 chr6:96969491 KIAA0776 -0.73 -7.23 -0.36 3.16e-12 Migraine;Coronary artery disease; LIHC cis rs2455799 0.613 rs62241264 chr3:15943471 T/C cg12698662 chr3:15914712 MIR563 -0.36 -6.67 -0.34 1e-10 Mean platelet volume; LIHC cis rs35306767 0.903 rs10904577 chr10:922077 A/G cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs797680 0.856 rs12044657 chr1:93639596 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.35 -6.07 -0.31 3.37e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs2153535 0.562 rs10458225 chr6:8386004 G/A cg23788917 chr6:8435910 SLC35B3 -0.62 -9.41 -0.45 7.74e-19 Motion sickness; LIHC cis rs921968 0.643 rs2556384 chr2:219532903 C/T cg18887096 chr2:219472410 PLCD4 -0.39 -6.69 -0.34 9.17e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs929354 0.742 rs2051877 chr7:157008813 A/T cg17757837 chr7:157058334 UBE3C 0.74 12.04 0.55 4.35e-28 Body mass index; LIHC cis rs4563143 0.514 rs73030738 chr19:29312328 G/A cg14983838 chr19:29218262 NA 0.41 6.1 0.31 2.8e-9 Methadone dose in opioid dependence; LIHC cis rs10876993 0.928 rs1689595 chr12:58056763 C/T cg18357645 chr12:58087776 OS9 0.51 8.51 0.42 5.66e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs2073499 0.872 rs41291724 chr3:50294066 C/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.68 6.62 0.34 1.38e-10 Schizophrenia; LIHC cis rs748404 0.650 rs518234 chr15:43573421 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.02 0.35 1.21e-11 Lung cancer; LIHC cis rs6500602 0.598 rs3859155 chr16:4593741 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.41 -6.17 -0.32 1.88e-9 Schizophrenia; LIHC trans rs4596713 0.507 rs2275427 chr9:71792581 G/A cg16512924 chr15:28394682 HERC2 0.38 6.17 0.32 1.97e-9 Headache; LIHC cis rs1865721 0.958 rs11663060 chr18:73172806 T/C cg26385618 chr18:73139727 C18orf62 -0.29 -7.28 -0.37 2.3e-12 Intelligence; LIHC cis rs7312933 0.703 rs10880264 chr12:42586535 A/G cg01256987 chr12:42539512 GXYLT1 -0.4 -6.68 -0.34 9.46e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7572733 0.555 rs6434954 chr2:198929716 T/C cg00792783 chr2:198669748 PLCL1 0.42 5.99 0.31 5.18e-9 Dermatomyositis; LIHC cis rs7927771 1.000 rs34128973 chr11:47851376 C/T cg20307385 chr11:47447363 PSMC3 -0.44 -5.75 -0.3 1.98e-8 Subjective well-being; LIHC cis rs7903847 0.642 rs10882909 chr10:99137998 G/C cg08345082 chr10:99160200 RRP12 -0.38 -6.26 -0.32 1.16e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7512552 0.839 rs12045304 chr1:150399818 G/A cg15654264 chr1:150340011 RPRD2 0.69 11.23 0.52 4.11e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs7089973 0.564 rs55671354 chr10:116571281 T/C cg03647239 chr10:116582469 FAM160B1 0.46 6.38 0.33 5.9e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs8103278 0.740 rs2341097 chr19:46268902 C/T cg02376097 chr19:46275166 DMPK -0.43 -6.69 -0.34 9.2e-11 Coronary artery disease; LIHC cis rs4700695 0.764 rs152941 chr5:65241446 A/G cg21114390 chr5:65439923 SFRS12 0.44 5.77 0.3 1.8e-8 Facial morphology (factor 19); LIHC trans rs10761482 0.639 rs2067612 chr10:62212334 T/C cg17314160 chr12:110399253 GIT2 -0.4 -6.05 -0.31 3.73e-9 Schizophrenia; LIHC cis rs9911578 0.967 rs6503893 chr17:57149695 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -8.99 -0.44 1.67e-17 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg07677032 chr17:61819896 STRADA 0.44 6.42 0.33 4.45e-10 Prudent dietary pattern; LIHC cis rs11229555 0.574 rs11603800 chr11:58202085 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs3806843 0.676 rs2245640 chr5:140029958 A/G cg19875535 chr5:140030758 IK -0.44 -7.24 -0.36 2.98e-12 Depressive symptoms (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18040892 chr19:11144017 SMARCA4 -0.38 -6.44 -0.33 3.95e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs13161895 0.941 rs6876648 chr5:179441842 T/C cg06664874 chr5:179499304 RNF130 -0.58 -7.22 -0.36 3.48e-12 LDL cholesterol; LIHC cis rs9902453 0.817 rs3115089 chr17:28031881 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 12.2 0.55 1.15e-28 Coffee consumption (cups per day); LIHC trans rs1075232 0.655 rs77987193 chr15:31588258 C/G cg04373760 chr16:53404718 NA 0.65 6.25 0.32 1.24e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs13108904 0.539 rs13145722 chr4:1338422 T/A cg13395646 chr4:1353034 KIAA1530 -0.8 -12.02 -0.54 5.38e-28 Obesity-related traits; LIHC cis rs7582720 1.000 rs72926782 chr2:203811628 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9733 0.596 rs7412396 chr1:150666797 C/T cg13175981 chr1:150552382 MCL1 -0.45 -6.32 -0.32 7.95e-10 Tonsillectomy; LIHC cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.11 -0.61 6.26e-36 Alzheimer's disease; LIHC cis rs1062177 1.000 rs2915869 chr5:151171509 C/T cg00977110 chr5:151150581 G3BP1 0.55 6.98 0.35 1.56e-11 Preschool internalizing problems; LIHC cis rs35883536 0.967 rs4908090 chr1:101135177 A/G cg14515779 chr1:101123966 NA -0.68 -13.54 -0.59 9.39e-34 Monocyte count; LIHC cis rs597539 0.652 rs482172 chr11:68668437 C/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.0 0.51 2.63e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs35306767 0.903 rs34847097 chr10:902252 A/T cg26597838 chr10:835615 NA 1.17 13.75 0.6 1.47e-34 Eosinophil percentage of granulocytes; LIHC cis rs7412746 0.658 rs10305704 chr1:150804429 A/C cg18016565 chr1:150552671 MCL1 0.54 10.31 0.49 6.79e-22 Melanoma; LIHC cis rs6732160 0.525 rs2303907 chr2:73470497 T/C cg24220031 chr2:73402428 NA -0.28 -5.96 -0.31 6.36e-9 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg14671364 chr1:107599128 PRMT6 -0.51 -7.54 -0.38 4.23e-13 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9303401 0.659 rs7225896 chr17:56637337 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.97 12.98 0.57 1.38e-31 Cognitive test performance; LIHC cis rs2404602 0.735 rs4886798 chr15:76673226 A/G cg03037974 chr15:76606532 NA 0.64 11.26 0.52 3.2e-25 Blood metabolite levels; LIHC cis rs1865760 0.892 rs2328903 chr6:25935765 T/C cg03517284 chr6:25882590 NA -0.44 -6.64 -0.34 1.21e-10 Height; LIHC cis rs7945705 0.692 rs11042149 chr11:9010737 T/C cg12365402 chr11:9010492 NRIP3 -0.3 -8.05 -0.4 1.39e-14 Hemoglobin concentration; LIHC cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg17554472 chr22:41940697 POLR3H 0.56 6.08 0.31 3.2e-9 Vitiligo; LIHC cis rs2066819 1.000 rs11575232 chr12:56744422 G/A cg26714650 chr12:56694279 CS -1.35 -12.74 -0.57 1.09e-30 Psoriasis vulgaris; LIHC cis rs11711311 1.000 rs2712348 chr3:113460614 C/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.25 0.41 3.56e-15 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08882882 chr6:84937375 KIAA1009 0.46 6.29 0.32 9.7e-10 Pancreatic cancer; LIHC trans rs2727020 0.615 rs4980435 chr11:49591576 G/A cg03929089 chr4:120376271 NA -0.9 -18.14 -0.7 5.33e-52 Coronary artery disease; LIHC cis rs28830936 1.000 rs28830936 chr15:41906408 G/A cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.85 -0.3 1.17e-8 Diastolic blood pressure; LIHC cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg27297192 chr10:134578999 INPP5A 0.55 8.06 0.4 1.3e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1577917 0.655 rs9444352 chr6:86257535 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.37 6.61 0.34 1.48e-10 Response to antipsychotic treatment; LIHC cis rs6684514 1.000 rs3806408 chr1:156252137 C/A cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs651907 0.535 rs13084113 chr3:101534039 C/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.63 9.99 0.48 8.38e-21 Colorectal cancer; LIHC cis rs2710642 0.721 rs10177638 chr2:62887010 C/T cg17519650 chr2:63277830 OTX1 0.47 6.83 0.35 3.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs9560113 1.000 rs4773386 chr13:112180896 C/G cg14154082 chr13:112174009 NA 0.29 6.17 0.32 1.94e-9 Menarche (age at onset); LIHC cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg09904177 chr6:26538194 HMGN4 0.57 11.51 0.53 3.79e-26 Intelligence (multi-trait analysis); LIHC cis rs9309473 0.583 rs6709853 chr2:73576065 T/A cg20560298 chr2:73613845 ALMS1 -0.45 -7.24 -0.36 2.93e-12 Metabolite levels; LIHC cis rs9649213 0.593 rs7796611 chr7:97908223 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.88 -0.3 9.77e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg24503407 chr1:205819492 PM20D1 0.72 10.23 0.48 1.34e-21 Menarche (age at onset); LIHC cis rs875971 0.825 rs28480509 chr7:66099224 A/G cg18876405 chr7:65276391 NA -0.34 -6.16 -0.32 2.07e-9 Aortic root size; LIHC cis rs7326068 0.504 rs7983020 chr13:21239941 C/T cg27234864 chr13:21295941 IL17D -0.39 -6.09 -0.31 3.01e-9 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs2522056 1.000 rs2057655 chr5:131807624 A/G cg24060327 chr5:131705240 SLC22A5 -0.53 -7.14 -0.36 5.54e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs13108904 0.875 rs1564509 chr4:1236562 C/G cg13395646 chr4:1353034 KIAA1530 -0.5 -8.2 -0.41 4.89e-15 Obesity-related traits; LIHC cis rs7615952 0.599 rs6766327 chr3:125723677 C/G cg05084668 chr3:125655381 ALG1L -0.4 -6.46 -0.33 3.66e-10 Blood pressure (smoking interaction); LIHC cis rs10789491 1.000 rs2083485 chr1:47170091 G/C cg15501359 chr1:47185051 KIAA0494 0.77 10.99 0.51 2.84e-24 Response to hepatitis C treatment; LIHC cis rs1005277 0.579 rs1780145 chr10:38537070 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.46 -6.6 -0.34 1.54e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6598955 0.515 rs61776655 chr1:26541430 T/C cg00852783 chr1:26633632 UBXN11 0.48 8.02 0.4 1.73e-14 Obesity-related traits; LIHC cis rs9527 0.637 rs7096169 chr10:104618695 A/G cg15744005 chr10:104629667 AS3MT -0.45 -10.31 -0.49 6.86e-22 Arsenic metabolism; LIHC trans rs60843830 1.000 rs7605824 chr2:280819 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 -0.66 -9.4 -0.45 7.79e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg20887711 chr4:1340912 KIAA1530 0.81 12.47 0.56 1.12e-29 Longevity; LIHC cis rs9916302 0.904 rs8070695 chr17:37478062 C/T cg07936489 chr17:37558343 FBXL20 0.8 13.23 0.58 1.47e-32 Glomerular filtration rate (creatinine); LIHC cis rs17376456 0.569 rs10067754 chr5:93093110 T/A cg25358565 chr5:93447407 FAM172A 0.8 7.68 0.38 1.63e-13 Diabetic retinopathy; LIHC cis rs208520 1.000 rs9453671 chr6:66991208 A/G cg07460842 chr6:66804631 NA 0.66 7.23 0.36 3.2e-12 Exhaled nitric oxide output; LIHC cis rs2073300 0.609 rs74273791 chr20:23418067 A/T cg16736954 chr20:23401023 NAPB 0.71 8.21 0.41 4.5e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg20295408 chr7:1910781 MAD1L1 -0.41 -5.97 -0.31 6.08e-9 Schizophrenia; LIHC cis rs2073300 1.000 rs6137971 chr20:23456429 G/T cg12062639 chr20:23401060 NAPB 0.84 9.82 0.47 3.16e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs77633900 0.614 rs280030 chr15:77026853 T/C cg21673338 chr15:77095150 SCAPER -0.47 -7.12 -0.36 6.6e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs5769765 0.542 rs5770720 chr22:50253101 A/G cg09182678 chr22:50328711 NA 0.47 6.0 0.31 5.14e-9 Schizophrenia; LIHC cis rs1355223 0.867 rs3818514 chr11:34680053 G/A cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.17 -0.32 1.98e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs1814175 0.617 rs6486020 chr11:49769149 T/G cg18944383 chr4:111397179 ENPEP 0.27 6.97 0.35 1.66e-11 Height; LIHC cis rs9611565 0.512 rs2899347 chr22:42158204 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.29 0.49 7.98e-22 Vitiligo; LIHC cis rs7116495 0.609 rs10751191 chr11:71680920 C/T cg26138937 chr11:71823887 C11orf51 -1.31 -10.34 -0.49 5.49e-22 Severe influenza A (H1N1) infection; LIHC cis rs2354432 1.000 rs7514864 chr1:146690102 T/C cg25205988 chr1:146714368 CHD1L 0.91 12.6 0.56 3.57e-30 Mitochondrial DNA levels; LIHC cis rs4773330 1.000 rs1891958 chr13:111817665 C/T cg26911804 chr13:111806221 ARHGEF7 -0.63 -6.47 -0.33 3.44e-10 Bilirubin levels; LIHC cis rs7552404 1.000 rs4949674 chr1:76213715 C/A cg10523679 chr1:76189770 ACADM 0.63 8.78 0.43 7.88e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2180341 1.000 rs3798853 chr6:127636823 C/T cg24812749 chr6:127587940 RNF146 -0.97 -13.55 -0.59 9.21e-34 Breast cancer; LIHC cis rs9649213 0.593 rs56286037 chr7:98019522 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.8 -0.3 1.53e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs1003719 0.788 rs2835586 chr21:38461326 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs61677309 1.000 rs894677 chr11:118172535 C/T cg06090739 chr11:118230722 UBE4A 0.35 6.44 0.33 4.11e-10 Lung cancer in ever smokers; LIHC cis rs1580019 0.665 rs34147895 chr7:32531796 G/C cg14728415 chr7:32535168 LSM5;AVL9 0.45 6.53 0.33 2.36e-10 Cognitive ability; LIHC cis rs1023500 0.573 rs133378 chr22:42467695 G/C cg15557168 chr22:42548783 NA -0.42 -6.69 -0.34 8.95e-11 Schizophrenia; LIHC cis rs1707322 0.963 rs4630155 chr1:46257110 G/C cg03146154 chr1:46216737 IPP 0.49 7.71 0.38 1.38e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4700695 0.841 rs428880 chr5:65245133 C/A cg21114390 chr5:65439923 SFRS12 0.44 5.77 0.3 1.8e-8 Facial morphology (factor 19); LIHC cis rs1639906 0.895 rs6972752 chr7:2196551 G/A cg04267008 chr7:1944627 MAD1L1 0.47 6.11 0.31 2.69e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg25204440 chr1:209979598 IRF6 0.43 6.56 0.33 2.04e-10 Cleft lip with or without cleft palate; LIHC cis rs2153535 0.580 rs9406167 chr6:8502852 T/C cg21535247 chr6:8435926 SLC35B3 0.6 7.87 0.39 4.6e-14 Motion sickness; LIHC cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.5 -7.58 -0.38 3.23e-13 Prudent dietary pattern; LIHC cis rs1707322 0.721 rs10789470 chr1:46158331 T/G cg06784218 chr1:46089804 CCDC17 0.42 7.74 0.39 1.11e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15290081 chr7:76254647 POMZP3;LOC100133091 0.5 7.01 0.35 1.27e-11 Systolic blood pressure; LIHC cis rs9457247 1.000 rs1819333 chr6:167373547 G/T cg12798992 chr6:167411361 FGFR1OP 0.64 10.64 0.5 4.8e-23 Crohn's disease; LIHC cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.5 0.46 3.65e-19 Bipolar disorder; LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.54 7.57 0.38 3.4e-13 Lymphocyte counts; LIHC cis rs9649465 1.000 rs13230294 chr7:123380821 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.19 -0.41 5.09e-15 Migraine; LIHC cis rs6461049 0.646 rs3778970 chr7:2143208 C/A cg04267008 chr7:1944627 MAD1L1 -0.53 -8.21 -0.41 4.7e-15 Schizophrenia; LIHC trans rs800082 0.668 rs6805395 chr3:144292116 T/C cg24215973 chr2:240111563 HDAC4 -0.58 -8.85 -0.43 4.92e-17 Smoking behavior; LIHC cis rs5769765 1.000 rs34774661 chr22:50267508 C/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs507080 0.961 rs607527 chr11:118538187 A/C cg04173919 chr11:118528438 PHLDB1 -0.31 -5.83 -0.3 1.27e-8 Serum metabolite levels; LIHC cis rs2963155 0.518 rs72801090 chr5:142774692 C/T cg17617527 chr5:142782415 NR3C1 0.91 10.43 0.49 2.72e-22 Breast cancer; LIHC cis rs6938 0.618 rs12912839 chr15:75221245 C/T cg14664628 chr15:75095509 CSK -0.47 -5.84 -0.3 1.21e-8 Breast cancer; LIHC cis rs17106184 0.681 rs12058197 chr1:51284557 T/C cg07174182 chr1:51127561 FAF1 -0.65 -7.21 -0.36 3.53e-12 Type 2 diabetes; LIHC cis rs875971 0.862 rs10282433 chr7:65721439 G/A cg11764359 chr7:65958608 NA -0.84 -14.85 -0.63 7.54e-39 Aortic root size; LIHC cis rs7818688 0.697 rs11782590 chr8:95970158 G/C cg16049864 chr8:95962084 TP53INP1 0.56 6.33 0.32 7.59e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6960043 1.000 rs62448644 chr7:15053485 C/T cg19272540 chr7:15055459 NA -0.22 -6.13 -0.31 2.43e-9 Type 2 diabetes; LIHC cis rs7940866 0.845 rs1991899 chr11:130801649 C/T cg12179176 chr11:130786555 SNX19 -0.58 -8.53 -0.42 4.82e-16 Schizophrenia; LIHC cis rs9948 1.000 rs6576986 chr2:97508320 G/C cg01990225 chr2:97406019 LMAN2L -0.59 -5.99 -0.31 5.19e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs4409675 0.576 rs12062621 chr1:28230404 A/G cg23691781 chr1:28212827 C1orf38 0.3 7.34 0.37 1.54e-12 Corneal astigmatism; LIHC trans rs1814175 0.645 rs1851850 chr11:50012168 G/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs2153535 0.580 rs962590 chr6:8450899 A/G cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC cis rs10197940 0.810 rs4664045 chr2:152267072 T/G cg06191203 chr2:152266755 RIF1 -0.51 -9.65 -0.46 1.17e-19 Lung cancer; LIHC cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg24549020 chr5:56110836 MAP3K1 0.52 6.68 0.34 9.48e-11 Initial pursuit acceleration; LIHC cis rs263063 0.920 rs263057 chr19:5037351 A/G cg18473234 chr19:5097819 KDM4B -0.54 -6.72 -0.34 7.76e-11 Periodontitis (CDC/AAP); LIHC cis rs10871290 0.881 rs7498574 chr16:74472661 A/G cg01733217 chr16:74700730 RFWD3 -0.45 -7.69 -0.38 1.6e-13 Breast cancer; LIHC cis rs1059312 1.000 rs9738216 chr12:129281788 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.69 -13.62 -0.59 4.66e-34 Systemic lupus erythematosus; LIHC cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg03264133 chr6:25882463 NA -0.8 -11.9 -0.54 1.46e-27 Blood metabolite levels; LIHC cis rs600806 0.813 rs4970760 chr1:109985439 A/G cg23091122 chr1:110024289 SYPL2 -0.49 -6.55 -0.33 2.15e-10 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.894 rs71367985 chr17:41374463 G/A cg25072359 chr17:41440525 NA 0.36 5.8 0.3 1.49e-8 Menopause (age at onset); LIHC trans rs3780486 0.505 rs7868663 chr9:33141229 A/G cg04842962 chr6:43655489 MRPS18A 0.89 18.83 0.71 8.72e-55 IgG glycosylation; LIHC cis rs4555082 0.834 rs2816631 chr14:105739477 G/A cg10792982 chr14:105748885 BRF1 0.5 6.56 0.33 2.05e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs2153535 0.541 rs6905934 chr6:8440043 C/A cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs9325144 0.560 rs6582539 chr12:38630097 C/T cg26384229 chr12:38710491 ALG10B -0.6 -8.17 -0.4 6.13e-15 Morning vs. evening chronotype; LIHC cis rs7772486 0.681 rs9390343 chr6:146010527 A/T cg23711669 chr6:146136114 FBXO30 -0.55 -9.37 -0.45 9.81e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs6430585 0.793 rs11684545 chr2:136539122 G/T cg25344623 chr2:136566232 LCT 0.45 8.88 0.43 3.71e-17 Corneal structure; LIHC cis rs9309473 0.607 rs1522927 chr2:73556155 T/G cg20560298 chr2:73613845 ALMS1 -0.41 -6.4 -0.33 5.23e-10 Metabolite levels; LIHC trans rs208520 1.000 rs12194996 chr6:66973366 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.7 0.34 8.37e-11 Exhaled nitric oxide output; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.76 -14.18 -0.61 3.2e-36 Prudent dietary pattern; LIHC cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg20887711 chr4:1340912 KIAA1530 0.49 7.65 0.38 2.09e-13 Obesity-related traits; LIHC cis rs11758351 1.000 rs17598927 chr6:26184640 C/G cg16070018 chr6:26224392 HIST1H3E -0.62 -7.5 -0.38 5.55e-13 Gout;Renal underexcretion gout; LIHC cis rs7116495 0.609 rs4245463 chr11:71743213 C/A cg26138937 chr11:71823887 C11orf51 -1.33 -10.54 -0.5 1.07e-22 Severe influenza A (H1N1) infection; LIHC cis rs9916302 0.680 rs2271308 chr17:37817482 T/C cg00129232 chr17:37814104 STARD3 -0.55 -10.1 -0.48 3.58e-21 Glomerular filtration rate (creatinine); LIHC cis rs7613875 0.663 rs6762477 chr3:50093209 G/A cg24110177 chr3:50126178 RBM5 0.56 9.12 0.44 6.64e-18 Body mass index; LIHC cis rs80282103 0.867 rs7075830 chr10:1091650 G/C cg08668510 chr10:1095578 IDI1 0.74 7.38 0.37 1.18e-12 Glomerular filtration rate (creatinine); LIHC cis rs12971120 1.000 rs2278162 chr18:72175814 A/G cg25817165 chr18:72167213 CNDP2 -0.71 -12.55 -0.56 5.82e-30 Refractive error; LIHC cis rs1499614 1.000 rs2141924 chr7:66186246 C/T cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs881375 0.526 rs1930785 chr9:123691237 T/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.41 5.85 0.3 1.17e-8 Rheumatoid arthritis; LIHC cis rs17685 0.697 rs28689051 chr7:75763624 G/A cg16684958 chr7:75615977 POR 0.51 8.49 0.42 6.55e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3008870 0.959 rs3008852 chr1:67383416 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.6 0.67 8.6e-46 Lymphocyte percentage of white cells; LIHC cis rs2302190 0.882 rs9901693 chr17:56606915 C/T cg12560992 chr17:57184187 TRIM37 0.69 8.88 0.43 3.9e-17 Vitamin D levels; LIHC cis rs2463822 1.000 rs2513071 chr11:62098387 A/C cg06239285 chr11:62104954 ASRGL1 0.93 7.14 0.36 5.5e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs116248771 0.690 rs10936149 chr3:158293893 T/G cg16708174 chr3:158430962 RARRES1 0.47 6.21 0.32 1.54e-9 diarrhoeal disease at age 2; LIHC cis rs6701037 0.566 rs1883102 chr1:175136793 T/A cg00321850 chr1:175162397 KIAA0040 0.47 7.68 0.38 1.72e-13 Alcohol dependence; LIHC cis rs17776563 0.959 rs1348004 chr15:89113450 C/G cg05013243 chr15:89149849 MIR1179 0.45 7.56 0.38 3.66e-13 Thyroid hormone levels; LIHC cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg22907277 chr7:1156413 C7orf50 0.52 7.85 0.39 5.41e-14 Longevity;Endometriosis; LIHC cis rs6586163 0.527 rs3824730 chr10:90752128 A/T cg03111039 chr10:90751583 FAS;ACTA2 0.8 12.79 0.57 7e-31 Chronic lymphocytic leukemia; LIHC cis rs2404602 0.660 rs11852777 chr15:76929792 A/G cg03037974 chr15:76606532 NA -0.61 -10.16 -0.48 2.26e-21 Blood metabolite levels; LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg24503407 chr1:205819492 PM20D1 0.73 10.24 0.48 1.21e-21 Menarche (age at onset); LIHC cis rs2576037 0.526 rs2051292 chr18:44484372 C/G cg24750912 chr18:44543259 TCEB3CL;KATNAL2 0.34 6.05 0.31 3.8e-9 Personality dimensions; LIHC cis rs11671005 0.735 rs11878198 chr19:58920302 A/G cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs7224737 1.000 rs9889640 chr17:40293497 C/T cg02450064 chr17:40260053 DHX58 -0.3 -6.15 -0.32 2.17e-9 Fibrinogen levels; LIHC trans rs2739330 0.731 rs5751792 chr22:24401542 G/A cg06437703 chr8:37914619 EIF4EBP1 -0.81 -13.87 -0.6 5.03e-35 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2412488 0.893 rs2271558 chr4:54362833 A/G cg22241045 chr4:54363911 LNX1 0.46 7.64 0.38 2.15e-13 DNA methylation (variation); LIHC cis rs1914816 0.941 rs2460146 chr15:76554755 C/T cg03037974 chr15:76606532 NA -0.61 -6.4 -0.33 5.1e-10 Response to tocilizumab in rheumatoid arthritis; LIHC trans rs9500256 0.966 rs1322446 chr6:58311950 C/T cg03371099 chr6:57305889 PRIM2 -0.37 -6.43 -0.33 4.34e-10 Eosinophilic esophagitis (pediatric); LIHC trans rs10028773 0.506 rs12374346 chr4:120281705 G/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Educational attainment; LIHC cis rs11792861 0.855 rs72607165 chr9:111814498 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.84 0.43 5.31e-17 Menarche (age at onset); LIHC cis rs7216064 0.953 rs9890629 chr17:65871559 G/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.55 -0.46 2.62e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08843001 chr8:30891486 WRN;PURG 0.51 6.49 0.33 2.98e-10 Lung function (FEV1/FVC); LIHC cis rs11053548 0.614 rs10505745 chr12:10176144 A/G cg04314261 chr12:10163030 CLEC12B -0.37 -5.8 -0.3 1.48e-8 Systolic blood pressure in sickle cell anemia; LIHC cis rs2228479 0.702 rs17233176 chr16:89832751 G/C cg04013166 chr16:89971882 TCF25 0.52 6.46 0.33 3.55e-10 Skin colour saturation; LIHC cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.95 9.69 0.46 8.64e-20 Platelet count; LIHC cis rs2286885 1.000 rs10819171 chr9:129253074 G/A cg15282417 chr9:129245246 FAM125B 0.39 6.3 0.32 9.1e-10 Intraocular pressure; LIHC cis rs6912958 0.712 rs7772561 chr6:88331299 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.93 -0.39 3.2e-14 Monocyte percentage of white cells; LIHC trans rs62103177 0.714 rs12607447 chr18:77605212 A/G cg05926928 chr17:57297772 GDPD1 0.56 7.49 0.38 5.84e-13 Opioid sensitivity; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg11668770 chr19:56125740 NA 0.39 6.19 0.32 1.71e-9 Bipolar disorder; LIHC cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg07424592 chr7:64974309 NA -0.8 -9.32 -0.45 1.44e-18 Diabetic kidney disease; LIHC cis rs1728785 1.000 rs6499181 chr16:68593002 A/T cg02972257 chr16:68554789 NA -0.55 -6.21 -0.32 1.55e-9 Ulcerative colitis; LIHC cis rs1577917 0.958 rs1414199 chr6:86522370 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.27 -0.41 3e-15 Response to antipsychotic treatment; LIHC cis rs769267 0.930 rs10419912 chr19:19597055 A/G cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.19 -0.32 1.68e-9 Tonsillectomy; LIHC cis rs9393777 0.513 rs7740197 chr6:26663478 C/T cg12826209 chr6:26865740 GUSBL1 -0.55 -5.97 -0.31 5.9e-9 Intelligence (multi-trait analysis); LIHC cis rs6782228 0.606 rs2001950 chr3:128419756 A/G cg16766828 chr3:128327626 NA -0.37 -5.93 -0.31 7.47e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7937890 0.559 rs2597197 chr11:14489832 G/A cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs8141529 0.702 rs5762870 chr22:29261159 C/T cg02153584 chr22:29168773 CCDC117 0.5 7.99 0.4 2.07e-14 Lymphocyte counts; LIHC cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg18357526 chr6:26021779 HIST1H4A 0.54 6.68 0.34 9.93e-11 Blood metabolite levels; LIHC cis rs9868809 0.881 rs3821876 chr3:48668394 G/T cg07636037 chr3:49044803 WDR6 -0.55 -6.38 -0.33 5.74e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs6762 0.692 rs5030778 chr11:836008 T/C cg07691484 chr11:842764 TSPAN4;POLR2L -0.72 -9.28 -0.45 1.97e-18 Mean platelet volume; LIHC cis rs17125944 0.505 rs77949716 chr14:53204234 G/A cg13660082 chr14:53194042 PSMC6 -0.46 -7.52 -0.38 4.91e-13 Alzheimer's disease (late onset); LIHC cis rs1775715 0.870 rs1251400 chr10:32235145 A/G cg14930904 chr10:32216787 ARHGAP12 0.39 6.95 0.35 1.82e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9467773 0.525 rs1535274 chr6:26520747 A/C cg09904177 chr6:26538194 HMGN4 0.53 8.8 0.43 7.1e-17 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.770 rs2839984 chr21:47671690 A/G cg12379764 chr21:47803548 PCNT -0.55 -8.22 -0.41 4.2e-15 Testicular germ cell tumor; LIHC cis rs4638749 0.677 rs2100407 chr2:108830188 G/C cg25838818 chr2:108905173 SULT1C2 -0.4 -6.97 -0.35 1.68e-11 Blood pressure; LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg20887711 chr4:1340912 KIAA1530 0.6 9.29 0.45 1.82e-18 Obesity-related traits; LIHC cis rs7927592 0.731 rs643609 chr11:68241833 A/G cg16797656 chr11:68205561 LRP5 0.53 9.42 0.45 6.92e-19 Total body bone mineral density; LIHC cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg07424592 chr7:64974309 NA 0.75 8.79 0.43 7.66e-17 Diabetic kidney disease; LIHC cis rs9393777 0.528 rs7745603 chr6:27090404 C/T cg12826209 chr6:26865740 GUSBL1 0.46 5.72 0.3 2.36e-8 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg02993280 chr1:107599747 PRMT6 -0.64 -10.02 -0.48 7.1e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1941023 0.567 rs955019 chr11:60174250 C/T cg08716584 chr11:60157161 MS4A7 -0.31 -6.78 -0.34 5.41e-11 Congenital heart disease (maternal effect); LIHC cis rs72829446 0.530 rs66616380 chr17:7380188 C/A cg02795151 chr17:7402630 POLR2A 0.54 5.85 0.3 1.13e-8 Androgen levels; LIHC cis rs12908161 0.959 rs34784022 chr15:85231906 T/C cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC cis rs870825 0.929 rs871253 chr4:185589234 G/A cg04058563 chr4:185651563 MLF1IP 0.75 6.01 0.31 4.86e-9 Blood protein levels; LIHC cis rs4845459 0.967 rs4845446 chr1:152590750 C/T cg27206522 chr1:152595629 LCE3A 0.24 5.72 0.3 2.34e-8 Psoriasis; LIHC cis rs12887734 0.524 rs4900599 chr14:104283444 G/T cg01849466 chr14:104193079 ZFYVE21 -0.39 -5.89 -0.3 9.04e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs748404 0.660 rs690472 chr15:43764368 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.88 0.39 4.43e-14 Lung cancer; LIHC cis rs611744 0.836 rs684412 chr8:109210905 T/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs6089584 0.888 rs2146853 chr20:60617908 A/T cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC cis rs7617773 0.780 rs34523942 chr3:48342669 C/T cg11946769 chr3:48343235 NME6 0.89 11.56 0.53 2.56e-26 Coronary artery disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04185861 chr1:154377809 IL6R -0.46 -6.38 -0.33 5.82e-10 Systolic blood pressure; LIHC cis rs11644362 0.966 rs12933348 chr16:12991081 C/T cg06890432 chr16:12997467 SHISA9 -0.39 -6.72 -0.34 7.67e-11 Positive affect;Subjective well-being; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12445461 chr9:6681608 NA 0.46 6.52 0.33 2.6e-10 Pancreatic cancer; LIHC cis rs7927592 0.956 rs11228256 chr11:68251460 G/A cg16797656 chr11:68205561 LRP5 0.54 8.67 0.42 1.78e-16 Total body bone mineral density; LIHC cis rs7208859 0.673 rs61223749 chr17:29163747 G/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6456156 0.755 rs4710182 chr6:167514061 G/A cg07741184 chr6:167504864 NA 0.28 6.82 0.35 4.23e-11 Primary biliary cholangitis; LIHC cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg27297192 chr10:134578999 INPP5A 0.52 6.97 0.35 1.66e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs317689 0.600 rs478863 chr12:69639207 G/A cg20891283 chr12:69753455 YEATS4 0.47 6.52 0.33 2.49e-10 Response to diuretic therapy; LIHC cis rs2933343 0.621 rs728838 chr3:128589013 A/G cg25356066 chr3:128598488 ACAD9 0.53 7.46 0.37 7.4e-13 IgG glycosylation; LIHC cis rs2067615 0.579 rs9651957 chr12:107170128 A/G cg15890332 chr12:107067104 RFX4 0.26 6.04 0.31 3.95e-9 Heart rate; LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC trans rs6912958 0.712 rs4587138 chr6:88356915 G/C cg23605328 chr1:201951606 RNPEP 0.4 6.28 0.32 1e-9 Monocyte percentage of white cells; LIHC cis rs11030122 0.673 rs4910590 chr11:4018619 C/T cg18678763 chr11:4115507 RRM1 -0.56 -8.32 -0.41 2.15e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs861020 0.771 rs674804 chr1:210014603 C/G cg05527609 chr1:210001259 C1orf107 1.02 16.54 0.67 1.47e-45 Orofacial clefts; LIHC cis rs6502050 0.835 rs4789738 chr17:80123053 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs244731 0.959 rs3105419 chr5:176551396 G/C cg17509989 chr5:176798049 RGS14 0.66 6.18 0.32 1.86e-9 Urate levels in lean individuals; LIHC cis rs921968 0.565 rs608047 chr2:219615910 A/C cg02985541 chr2:219472218 PLCD4 0.38 6.58 0.34 1.8e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs7613875 0.600 rs1061474 chr3:50144951 T/C cg21659725 chr3:3221576 CRBN -0.53 -7.93 -0.39 3.15e-14 Body mass index; LIHC cis rs2439831 0.541 rs12440854 chr15:43610672 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.77 9.5 0.46 3.68e-19 Lung cancer in ever smokers; LIHC cis rs6952808 0.531 rs1107351 chr7:2177093 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.78 -0.3 1.68e-8 Bipolar disorder and schizophrenia; LIHC cis rs7845219 0.544 rs4735331 chr8:95917958 C/T cg16049864 chr8:95962084 TP53INP1 -0.44 -6.6 -0.34 1.58e-10 Type 2 diabetes; LIHC cis rs4555082 0.830 rs2735812 chr14:105727575 A/G cg10792982 chr14:105748885 BRF1 0.46 6.31 0.32 8.42e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 1.000 rs9834052 chr3:40399060 G/A cg00656387 chr3:40428638 ENTPD3 0.41 6.87 0.35 2.97e-11 Renal cell carcinoma; LIHC cis rs72781680 0.821 rs72790329 chr2:24129277 A/G cg08917208 chr2:24149416 ATAD2B 0.64 6.44 0.33 4.1e-10 Lymphocyte counts; LIHC cis rs11676348 0.846 rs4674257 chr2:218988774 A/G cg00012203 chr2:219082015 ARPC2 -0.55 -7.8 -0.39 7.5e-14 Ulcerative colitis; LIHC trans rs3780486 0.801 rs10971424 chr9:33138775 T/C cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs6430585 0.528 rs115469964 chr2:136696608 A/C cg07169764 chr2:136633963 MCM6 1.28 21.87 0.76 6.17e-67 Corneal structure; LIHC trans rs1005277 0.540 rs4934907 chr10:38015230 A/C cg23533926 chr12:111358616 MYL2 -0.32 -6.23 -0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7312933 0.703 rs11181378 chr12:42600658 T/C cg01256987 chr12:42539512 GXYLT1 -0.41 -6.8 -0.35 4.59e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11958404 0.932 rs72818109 chr5:157438340 A/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs921968 0.541 rs12987171 chr2:219327030 G/C cg02176678 chr2:219576539 TTLL4 0.55 7.72 0.39 1.27e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs4819052 0.851 rs8133045 chr21:46658137 A/G cg11663144 chr21:46675770 NA -0.33 -6.19 -0.32 1.76e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25742201 chr17:35306863 AATF -0.53 -6.83 -0.35 3.81e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1801251 0.778 rs778340 chr2:233734083 C/T cg08000102 chr2:233561755 GIGYF2 -0.7 -10.41 -0.49 3.1e-22 Coronary artery disease; LIHC cis rs2404602 0.583 rs11072580 chr15:76540231 G/A cg23625390 chr15:77176239 SCAPER 0.34 5.92 0.3 7.76e-9 Blood metabolite levels; LIHC cis rs1707322 0.717 rs1135850 chr1:46093692 G/A cg24296786 chr1:45957014 TESK2 -0.4 -5.75 -0.3 1.99e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2795502 1.000 rs2796575 chr10:43374911 A/G cg20628663 chr10:43360327 NA 0.46 7.05 0.36 1.02e-11 Blood protein levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08547432 chr19:50143419 RRAS 0.41 6.6 0.34 1.57e-10 Cognitive function; LIHC cis rs8072100 0.871 rs7206971 chr17:45425115 A/G cg08085267 chr17:45401833 C17orf57 0.59 8.94 0.44 2.45e-17 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4474465 0.850 rs10899545 chr11:78250371 C/T cg27205649 chr11:78285834 NARS2 0.4 6.26 0.32 1.14e-9 Alzheimer's disease (survival time); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg20546810 chr20:2489835 ZNF343 -0.42 -6.05 -0.31 3.77e-9 Immature fraction of reticulocytes; LIHC cis rs6120849 0.754 rs6120790 chr20:33599090 A/T cg24642439 chr20:33292090 TP53INP2 0.66 7.38 0.37 1.21e-12 Protein C levels; LIHC cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.15 -0.44 5.31e-18 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27658640 chr17:4843839 RNF167;SLC25A11 0.45 6.35 0.32 6.84e-10 Pancreatic cancer; LIHC cis rs9640161 0.750 rs11538922 chr7:150035183 C/T cg10018233 chr7:150070692 REPIN1 0.55 8.35 0.41 1.71e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs6762477 0.748 rs11711407 chr3:50225029 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.51 -8.1 -0.4 9.49e-15 Menarche (age at onset); LIHC cis rs2302190 0.882 rs7216856 chr17:56472295 C/T cg12560992 chr17:57184187 TRIM37 0.68 8.63 0.42 2.43e-16 Vitamin D levels; LIHC cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg18252515 chr7:66147081 NA 1.27 16.79 0.67 1.38e-46 Diabetic kidney disease; LIHC cis rs6088590 0.610 rs6120663 chr20:33081906 A/C cg08999081 chr20:33150536 PIGU -0.53 -8.48 -0.42 7.05e-16 Coronary artery disease; LIHC cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg13126279 chr21:47581558 C21orf56 -0.44 -7.25 -0.37 2.76e-12 Testicular germ cell tumor; LIHC cis rs7224737 1.000 rs12603327 chr17:40290552 T/C cg02450064 chr17:40260053 DHX58 -0.3 -6.15 -0.32 2.17e-9 Fibrinogen levels; LIHC cis rs7208859 0.623 rs7219361 chr17:29080393 G/A cg13385521 chr17:29058706 SUZ12P 0.78 7.74 0.39 1.15e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs16828019 0.777 rs12739052 chr1:41464455 C/A cg03962019 chr1:41807865 NA 0.53 7.01 0.35 1.26e-11 Intelligence (multi-trait analysis); LIHC trans rs60752752 0.852 rs12040625 chr1:153365548 A/G cg14901121 chr8:98817630 LAPTM4B -0.41 -6.86 -0.35 3.31e-11 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs2050392 0.624 rs303447 chr10:30728464 T/C cg25182066 chr10:30743637 MAP3K8 -0.61 -9.72 -0.47 7.19e-20 Inflammatory bowel disease; LIHC cis rs6960043 0.620 rs11760782 chr7:15064788 A/T cg19272540 chr7:15055459 NA 0.26 6.57 0.33 1.92e-10 Type 2 diabetes; LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg00800038 chr16:89945340 TCF25 -0.68 -10.66 -0.5 4.19e-23 Skin colour saturation; LIHC cis rs13191362 1.000 rs73035023 chr6:163000927 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9325144 0.560 rs11183189 chr12:38683770 T/A cg26384229 chr12:38710491 ALG10B 0.6 8.46 0.42 7.66e-16 Morning vs. evening chronotype; LIHC cis rs873946 0.586 rs11146503 chr10:134565388 T/C cg06453172 chr10:134556979 INPP5A -0.62 -7.72 -0.39 1.34e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6061231 1.000 rs67941642 chr20:60958108 C/T cg24112000 chr20:60950667 NA -0.63 -9.58 -0.46 2.14e-19 Colorectal cancer; LIHC cis rs12824058 0.831 rs12297939 chr12:130811923 G/C cg26677194 chr12:130822605 PIWIL1 0.51 7.25 0.36 2.88e-12 Menopause (age at onset); LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs116095464 0.558 rs10065239 chr5:275288 C/T cg22857025 chr5:266934 NA -1.52 -15.89 -0.65 5.89e-43 Breast cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg20870372 chr13:99867982 UBAC2 0.32 6.09 0.31 2.98e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs6108011 0.659 rs6117882 chr20:7589465 C/T cg13422339 chr21:47602486 C21orf56 0.5 6.21 0.32 1.57e-9 Hemostatic factors and hematological phenotypes; LIHC cis rs10464366 0.544 rs4355688 chr7:39158402 C/T cg20302533 chr7:39170763 POU6F2 0.38 6.95 0.35 1.8e-11 IgG glycosylation; LIHC cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg00684032 chr4:1343700 KIAA1530 0.51 7.3 0.37 1.98e-12 Obesity-related traits; LIHC trans rs35110281 0.805 rs2838319 chr21:44991901 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.44 6.07 0.31 3.47e-9 Mean corpuscular volume; LIHC cis rs11577318 0.579 rs11247936 chr1:26698884 A/G cg18121669 chr1:26560928 CCDC21 -0.47 -7.08 -0.36 8.33e-12 Granulocyte percentage of myeloid white cells; LIHC trans rs11098499 0.774 rs73842616 chr4:120290683 G/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg24250549 chr1:154909240 PMVK 0.66 10.11 0.48 3.38e-21 Prostate cancer; LIHC cis rs763121 0.853 rs138706 chr22:39137834 C/G cg14440974 chr22:39074834 NA -0.38 -6.49 -0.33 3.05e-10 Menopause (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg06030229 chr18:19321133 MIB1 0.51 6.26 0.32 1.15e-9 Hepatitis; LIHC cis rs910316 0.967 rs4899551 chr14:75660246 C/G cg08847533 chr14:75593920 NEK9 -0.84 -17.28 -0.68 1.55e-48 Height; LIHC cis rs11864453 0.762 rs6416742 chr16:72149061 C/T cg16558253 chr16:72132732 DHX38 -0.48 -7.17 -0.36 4.73e-12 Fibrinogen levels; LIHC cis rs9918079 0.560 rs4698409 chr4:15659766 G/A cg24225360 chr4:15471699 CC2D2A -0.39 -6.14 -0.32 2.29e-9 Obesity-related traits; LIHC cis rs1728785 1.000 rs12918861 chr16:68566508 G/A cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2.05e-9 Ulcerative colitis; LIHC cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg11890956 chr21:40555474 PSMG1 1.03 14.59 0.62 7.75e-38 Cognitive function; LIHC cis rs2250402 0.510 rs2291621 chr15:40324837 C/T cg10636054 chr15:40330586 SRP14 0.67 7.95 0.39 2.72e-14 Corneal curvature; LIHC cis rs2708977 0.842 rs10209780 chr2:97140142 T/G cg01950434 chr2:97203154 ARID5A -0.44 -6.42 -0.33 4.67e-10 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.56 0.53 2.64e-26 Alzheimer's disease; LIHC cis rs7223966 1.000 rs7223412 chr17:61808172 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.96 0.35 1.72e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg22520471 chr17:61851767 DDX42;CCDC47 0.77 12.95 0.57 1.76e-31 Prudent dietary pattern; LIHC cis rs9303280 0.806 rs2305480 chr17:38062196 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.83 0.3 1.28e-8 Self-reported allergy; LIHC cis rs4319547 0.915 rs1473553 chr12:122985057 G/T cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.09 -0.4 1.02e-14 Body mass index; LIHC cis rs4819052 0.819 rs8134084 chr21:46693295 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 11.81 0.54 3.03e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25457191 chr19:34895442 PDCD2L 0.46 6.21 0.32 1.53e-9 Lung function (FEV1/FVC); LIHC cis rs748404 0.533 rs11632120 chr15:43415373 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.35 -5.71 -0.3 2.41e-8 Lung cancer; LIHC cis rs826838 1.000 rs10506122 chr12:38699232 A/G cg13010199 chr12:38710504 ALG10B 0.64 7.73 0.39 1.22e-13 Heart rate; LIHC cis rs3818285 0.515 rs12258440 chr10:111676799 C/T cg00817464 chr10:111662876 XPNPEP1 -0.54 -8.64 -0.42 2.2e-16 Superior crus of antihelix expression; LIHC cis rs7129556 0.520 rs4366508 chr11:77274999 C/T cg03570279 chr11:77446074 RSF1 -0.36 -6.68 -0.34 9.43e-11 Weight loss (gastric bypass surgery); LIHC cis rs2204008 0.515 rs11495471 chr12:38027178 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.75 0.3 1.99e-8 Bladder cancer; LIHC cis rs1707322 0.964 rs1768802 chr1:46547868 A/G cg06784218 chr1:46089804 CCDC17 -0.37 -6.74 -0.34 6.8e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs116095464 0.558 rs7356561 chr5:284381 G/C cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC trans rs11098499 0.955 rs11944880 chr4:120159334 A/G cg25214090 chr10:38739885 LOC399744 -0.53 -8.17 -0.4 6.23e-15 Corneal astigmatism; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg02290350 chr8:58132656 NA 0.51 11.04 0.51 1.9e-24 Developmental language disorder (linguistic errors); LIHC trans rs9951602 0.512 rs58352488 chr18:76651113 T/A cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC cis rs2228479 0.717 rs2286392 chr16:89809549 A/G cg19635926 chr16:89946313 TCF25 0.46 6.0 0.31 4.94e-9 Skin colour saturation; LIHC cis rs7264396 0.563 rs6060569 chr20:34290731 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.52 -0.42 5.17e-16 Total cholesterol levels; LIHC cis rs3812831 0.695 rs10467349 chr13:114939441 A/G cg06611532 chr13:114900021 NA 0.42 7.76 0.39 9.7e-14 Schizophrenia; LIHC cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg00080972 chr5:178986291 RUFY1 -0.38 -5.74 -0.3 2.05e-8 Lung cancer; LIHC cis rs7707921 0.881 rs6875409 chr5:81297077 A/G cg15871215 chr5:81402204 ATG10 -0.63 -6.38 -0.33 5.7e-10 Breast cancer; LIHC cis rs77633900 0.614 rs2459363 chr15:76874952 T/C cg21673338 chr15:77095150 SCAPER -0.5 -7.24 -0.36 2.93e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.02 0.31 4.58e-9 Menopause (age at onset); LIHC cis rs1215050 0.791 rs1605259 chr4:98799732 T/C cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.86e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1215050 0.740 rs13134479 chr4:99067723 G/A cg05340658 chr4:99064831 C4orf37 0.4 6.15 0.32 2.11e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs929354 0.605 rs7806314 chr7:156946903 A/T cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs7188697 0.848 rs42947 chr16:58579158 A/C cg02549819 chr16:58548995 SETD6 -0.46 -7.25 -0.37 2.73e-12 QT interval; LIHC cis rs7727544 0.661 rs273900 chr5:131694606 G/A cg07395648 chr5:131743802 NA -0.31 -6.56 -0.33 2.05e-10 Blood metabolite levels; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg07677032 chr17:61819896 STRADA 0.42 6.13 0.31 2.49e-9 Prudent dietary pattern; LIHC cis rs68170813 0.559 rs77727587 chr7:106815754 C/G cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs992157 0.764 rs62183964 chr2:219186592 G/A cg00012203 chr2:219082015 ARPC2 0.77 10.96 0.51 3.85e-24 Colorectal cancer; LIHC cis rs4820539 0.966 rs2301554 chr22:23484254 A/C cg21100191 chr22:23484243 RTDR1 0.96 18.44 0.71 3.27e-53 Bone mineral density; LIHC cis rs2637266 0.756 rs846623 chr10:78542819 C/T cg18941641 chr10:78392320 NA 0.28 6.03 0.31 4.24e-9 Pulmonary function; LIHC cis rs873946 0.586 rs11146503 chr10:134565388 T/C cg18305652 chr10:134549665 INPP5A 0.41 5.94 0.31 6.99e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8084351 0.539 rs7504413 chr18:50610528 T/C cg24270629 chr18:50823537 DCC 0.44 6.73 0.34 7.31e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs6912958 0.712 rs7755167 chr6:88338752 T/C cg23605328 chr1:201951606 RNPEP 0.39 6.2 0.32 1.66e-9 Monocyte percentage of white cells; LIHC trans rs1005277 0.540 rs1814077 chr10:37992018 G/C cg17830980 chr10:43048298 ZNF37B -0.42 -8.05 -0.4 1.42e-14 Extrinsic epigenetic age acceleration; LIHC cis rs727505 1.000 rs77718560 chr7:124514544 T/A cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.1e-9 Lewy body disease; LIHC cis rs11083846 0.866 rs3786708 chr19:47248308 G/A cg08230695 chr19:47220755 PRKD2 0.62 6.28 0.32 1.04e-9 Chronic lymphocytic leukemia; LIHC cis rs67478160 0.625 rs7141473 chr14:104316055 A/C cg01849466 chr14:104193079 ZFYVE21 0.48 7.59 0.38 2.98e-13 Schizophrenia; LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg12923728 chr3:195709715 SDHAP1 -0.6 -6.93 -0.35 2.04e-11 Lung disease severity in cystic fibrosis; LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.19e-10 Developmental language disorder (linguistic errors); LIHC cis rs7914558 1.000 rs10883826 chr10:104830819 A/G cg15744005 chr10:104629667 AS3MT -0.37 -8.45 -0.42 8.33e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs611744 0.934 rs604698 chr8:109238721 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs11031096 0.617 rs12288918 chr11:4191466 G/T cg18678763 chr11:4115507 RRM1 -0.41 -5.95 -0.31 6.62e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs2018683 0.600 rs6948880 chr7:29003478 C/T cg19402173 chr7:128379420 CALU -0.38 -6.04 -0.31 4.02e-9 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs7918232 0.941 rs4749230 chr10:27441218 C/T cg14442939 chr10:27389572 ANKRD26 0.67 6.44 0.33 3.98e-10 Breast cancer; LIHC trans rs801193 0.660 rs1962050 chr7:66240008 C/T cg10756647 chr7:56101905 PSPH -0.47 -7.06 -0.36 9.56e-12 Aortic root size; LIHC cis rs7546668 0.895 rs10754894 chr1:15835234 G/A cg11706911 chr1:15910989 AGMAT 0.45 6.9 0.35 2.6e-11 Glomerular filtration rate (creatinine); LIHC cis rs9311474 0.607 rs4234633 chr3:52557038 C/T cg18404041 chr3:52824283 ITIH1 -0.44 -6.89 -0.35 2.68e-11 Electroencephalogram traits; LIHC cis rs2576037 0.526 rs2156050 chr18:44455873 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.56 0.5 9.43e-23 Personality dimensions; LIHC cis rs2153535 0.601 rs4960414 chr6:8438541 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.88 0.39 4.36e-14 Motion sickness; LIHC cis rs26868 0.766 rs26867 chr16:2249410 T/C cg25665528 chr16:2260870 C16orf79 -0.36 -6.32 -0.32 8.36e-10 Height; LIHC cis rs8072100 1.000 rs8072100 chr17:45674687 A/T cg08085267 chr17:45401833 C17orf57 0.58 8.65 0.42 2.01e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs1814175 0.817 rs7947286 chr11:49874657 C/T cg03929089 chr4:120376271 NA -0.89 -18.29 -0.7 1.34e-52 Height; LIHC cis rs11229555 0.645 rs7926682 chr11:58189495 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2839186 0.934 rs17182538 chr21:47705673 C/A cg09417038 chr21:47716443 C21orf57 -0.49 -7.21 -0.36 3.54e-12 Testicular germ cell tumor; LIHC cis rs9814567 0.806 rs9841371 chr3:134320765 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9818758 0.607 rs34784192 chr3:49274823 G/T cg00383909 chr3:49044727 WDR6 0.8 6.81 0.35 4.29e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg24209194 chr3:40518798 ZNF619 0.56 8.11 0.4 9.34e-15 Renal cell carcinoma; LIHC cis rs1568889 0.941 rs35357280 chr11:28322745 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.46 5.84 0.3 1.23e-8 Bipolar disorder; LIHC cis rs782590 0.967 rs11125579 chr2:55739804 T/C cg18811423 chr2:55921094 PNPT1 0.83 12.68 0.57 1.84e-30 Metabolic syndrome; LIHC cis rs769267 0.930 rs10282 chr19:19619317 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.0 0.31 5.11e-9 Tonsillectomy; LIHC cis rs3015497 0.646 rs3015492 chr14:51124743 G/A cg09863266 chr14:51125203 SAV1 -0.41 -5.8 -0.3 1.49e-8 Mean platelet volume; LIHC cis rs9790314 1.000 rs336589 chr3:161080358 C/T cg03342759 chr3:160939853 NMD3 -0.68 -8.06 -0.4 1.28e-14 Morning vs. evening chronotype; LIHC cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg21724239 chr8:58056113 NA 0.48 6.39 0.33 5.3e-10 Developmental language disorder (linguistic errors); LIHC cis rs9911578 0.692 rs411988 chr17:56709034 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.54 7.65 0.38 2.03e-13 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg02993280 chr1:107599747 PRMT6 0.67 10.98 0.51 3.13e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs826838 1.000 rs1684416 chr12:39130301 G/A cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs1973993 0.967 rs2181375 chr1:96940119 A/G cg10631902 chr5:14652156 NA 0.35 8.58 0.42 3.29e-16 Weight; LIHC cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6754311 0.517 rs1469996 chr2:136542560 A/G cg07169764 chr2:136633963 MCM6 1.03 13.27 0.58 1.03e-32 Mosquito bite size; LIHC cis rs2153535 0.580 rs9393033 chr6:8521446 G/A cg21535247 chr6:8435926 SLC35B3 0.63 8.31 0.41 2.3e-15 Motion sickness; LIHC cis rs2976388 0.609 rs2585145 chr8:143799457 G/A cg06565975 chr8:143823917 SLURP1 0.34 6.66 0.34 1.1e-10 Urinary tract infection frequency; LIHC cis rs9768139 0.708 rs60487292 chr7:158115342 G/A cg25566285 chr7:158114605 PTPRN2 0.23 6.22 0.32 1.43e-9 Calcium levels; LIHC trans rs11098499 0.954 rs17046116 chr4:120387259 G/A cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs6456156 0.524 rs6932740 chr6:167466439 G/A cg12798992 chr6:167411361 FGFR1OP 0.42 6.61 0.34 1.48e-10 Primary biliary cholangitis; LIHC cis rs6461049 0.638 rs1859993 chr7:2183702 A/G cg04267008 chr7:1944627 MAD1L1 -0.43 -6.68 -0.34 9.6e-11 Schizophrenia; LIHC cis rs7223966 1.000 rs16947005 chr17:61702989 C/T cg05941027 chr17:61774174 LIMD2 -0.32 -6.64 -0.34 1.25e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs895636 0.752 rs4245800 chr2:45189866 G/A cg16198908 chr2:45192207 NA 0.39 5.94 0.31 6.97e-9 Metabolite levels;Fasting plasma glucose; LIHC cis rs1866706 1.000 rs6486065 chr11:12870969 T/G cg25843174 chr11:12811716 TEAD1 -0.29 -6.14 -0.31 2.34e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg02290350 chr8:58132656 NA 0.42 8.88 0.43 3.83e-17 Developmental language disorder (linguistic errors); LIHC cis rs611744 0.647 rs589347 chr8:109253929 T/A cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27343303 chr11:34380546 NA 0.47 6.63 0.34 1.32e-10 Pancreatic cancer; LIHC cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg05552183 chr6:42928497 GNMT 0.81 12.02 0.55 5.2e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3823572 0.564 rs2346273 chr7:133659764 A/T cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg25364880 chr3:44379878 C3orf23 0.57 7.71 0.38 1.42e-13 Depressive symptoms; LIHC cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg04317338 chr11:64019027 PLCB3 0.87 10.83 0.51 1.04e-23 Mean platelet volume; LIHC cis rs6582630 0.519 rs8186881 chr12:38310285 A/G cg26384229 chr12:38710491 ALG10B 0.6 8.16 0.4 6.58e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs7520050 0.966 rs10789481 chr1:46383583 C/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.79 0.3 1.61e-8 Red blood cell count;Reticulocyte count; LIHC cis rs5769765 0.908 rs4074304 chr22:50309446 G/A cg09182678 chr22:50328711 NA -0.43 -6.17 -0.32 1.98e-9 Schizophrenia; LIHC cis rs963731 0.579 rs1454219 chr2:39276957 C/T cg04010122 chr2:39346883 SOS1 -0.61 -6.3 -0.32 9.37e-10 Corticobasal degeneration; LIHC cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg17971929 chr21:40555470 PSMG1 -0.52 -8.02 -0.4 1.72e-14 Cognitive function; LIHC cis rs4407350 0.967 rs5765741 chr22:44924292 A/G cg11695653 chr22:44894386 LDOC1L -0.36 -5.98 -0.31 5.75e-9 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC cis rs9549367 0.713 rs1323315 chr13:113859658 T/C cg18105134 chr13:113819100 PROZ 0.62 11.08 0.51 1.4e-24 Platelet distribution width; LIHC cis rs644799 1.000 rs3177463 chr11:95502128 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.82 0.47 3.18e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs736408 0.522 rs998909 chr3:52805093 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.22 0.36 3.39e-12 Bipolar disorder; LIHC cis rs2549003 1.000 rs2548997 chr5:131835395 C/T cg02551604 chr5:131831745 NA 0.49 7.44 0.37 8.22e-13 Asthma (sex interaction); LIHC cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg02891314 chr5:179741120 GFPT2 -0.43 -5.98 -0.31 5.54e-9 Height; LIHC cis rs7301016 0.846 rs73126024 chr12:63027764 C/T cg11441379 chr12:63026424 NA 0.61 6.22 0.32 1.45e-9 IgG glycosylation; LIHC cis rs16828019 0.852 rs12759050 chr1:41664204 T/A cg03962019 chr1:41807865 NA 0.53 7.64 0.38 2.27e-13 Intelligence (multi-trait analysis); LIHC cis rs66887589 0.934 rs7681980 chr4:120533223 G/A cg09307838 chr4:120376055 NA -0.47 -7.02 -0.35 1.2e-11 Diastolic blood pressure; LIHC trans rs1814175 0.712 rs9665784 chr11:50030617 C/T cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs2842992 0.789 rs7758895 chr6:160193465 T/C cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.24 0.55 7.91e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs909341 0.537 rs13041528 chr20:62385446 C/G cg14758556 chr20:62440591 NA -0.41 -6.58 -0.34 1.74e-10 Atopic dermatitis; LIHC cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg26818010 chr10:134567672 INPP5A -0.77 -9.36 -0.45 1.08e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1144333 0.655 rs4949682 chr1:76443196 C/T cg03433033 chr1:76189801 ACADM -0.55 -7.62 -0.38 2.44e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs9322817 0.691 rs2499667 chr6:105319125 G/A cg02098413 chr6:105308735 HACE1 0.42 7.71 0.38 1.35e-13 Thyroid stimulating hormone; LIHC trans rs76485637 0.761 rs71374973 chr16:8000380 A/T cg15006175 chr8:145698660 KIFC2 -0.33 -6.06 -0.31 3.54e-9 Pediatric bone mineral density (spine); LIHC cis rs921968 0.643 rs483172 chr2:219428299 A/G cg17980119 chr2:219472607 PLCD4 0.34 5.79 0.3 1.57e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs9649465 1.000 rs6466881 chr7:123337734 G/C cg03229431 chr7:123269106 ASB15 -0.38 -8.04 -0.4 1.44e-14 Migraine; LIHC cis rs13064411 0.696 rs2399479 chr3:113227050 G/A cg18753928 chr3:113234510 CCDC52 -0.44 -6.21 -0.32 1.52e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02895995 chr19:7554069 PEX11G 0.37 6.14 0.32 2.25e-9 Cognitive function; LIHC cis rs6547741 0.967 rs4665995 chr2:27813827 T/G cg27432699 chr2:27873401 GPN1 0.72 11.61 0.53 1.73e-26 Oral cavity cancer; LIHC cis rs9921222 0.500 rs12917907 chr16:405866 C/T cg00101154 chr16:420108 MRPL28 -0.59 -8.44 -0.42 8.81e-16 Bone mineral density (spine);Bone mineral density; LIHC cis rs10493773 0.618 rs34746573 chr1:86075360 G/A cg17807903 chr1:86174739 ZNHIT6 -0.49 -6.86 -0.35 3.21e-11 Urate levels in overweight individuals; LIHC cis rs2806561 0.704 rs588387 chr1:23523689 A/G cg19743168 chr1:23544995 NA 0.36 5.93 0.31 7.52e-9 Height; LIHC cis rs4319547 1.000 rs7307735 chr12:123087442 A/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.23 -0.36 3.28e-12 Body mass index; LIHC cis rs1065852 0.906 rs9611734 chr22:42502070 A/G cg20195005 chr22:42527684 CYP2D6 0.31 5.96 0.31 6.26e-9 Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels); LIHC cis rs941873 0.835 rs4246944 chr10:81105684 C/T cg09469691 chr10:81107165 PPIF 0.67 10.41 0.49 3.25e-22 Height; LIHC trans rs6600671 0.967 rs12069545 chr1:121172203 A/G cg09829573 chr1:144692074 NBPF9 -0.45 -8.23 -0.41 4.12e-15 Hip geometry; LIHC cis rs5770917 1.000 rs17848459 chr22:51012311 G/T cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.42 -6.14 -0.32 2.31e-9 Narcolepsy; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg26338869 chr17:61819248 STRADA 0.61 8.84 0.43 5.28e-17 Prudent dietary pattern; LIHC cis rs801193 0.904 rs4718405 chr7:66254646 A/G cg18252515 chr7:66147081 NA -0.44 -5.76 -0.3 1.93e-8 Aortic root size; LIHC cis rs3784262 0.607 rs4646576 chr15:58338998 A/T cg12031962 chr15:58353849 ALDH1A2 -0.37 -7.06 -0.36 9.52e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs713477 0.967 rs4898865 chr14:55910998 G/A cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.32e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs6456156 0.586 rs12528689 chr6:167461746 A/G cg07741184 chr6:167504864 NA 0.29 6.93 0.35 2.04e-11 Primary biliary cholangitis; LIHC cis rs1008375 0.966 rs4698621 chr4:17587565 C/T cg16339924 chr4:17578868 LAP3 0.46 6.35 0.32 6.66e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10489202 0.612 rs3820401 chr1:168074753 T/C cg24449463 chr1:168025552 DCAF6 -0.54 -8.36 -0.41 1.57e-15 Schizophrenia; LIHC cis rs10779751 0.690 rs910661 chr1:11130116 C/A cg08854313 chr1:11322531 MTOR 0.67 10.21 0.48 1.56e-21 Body mass index; LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg13409248 chr3:40428643 ENTPD3 0.47 7.71 0.38 1.38e-13 Renal cell carcinoma; LIHC cis rs9399135 0.967 rs9376082 chr6:135346389 T/A cg24558204 chr6:135376177 HBS1L 0.4 6.51 0.33 2.72e-10 Red blood cell count; LIHC cis rs9303401 0.614 rs8081058 chr17:57160513 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.46 0.56 1.24e-29 Cognitive test performance; LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg04025307 chr7:1156635 C7orf50 0.58 10.12 0.48 3.02e-21 Longevity;Endometriosis; LIHC cis rs4713118 0.513 rs149945 chr6:28002853 T/C cg23485639 chr6:28045615 ZNF165 0.39 5.94 0.31 7.13e-9 Parkinson's disease; LIHC cis rs2176862 1.000 rs77406377 chr3:46620961 T/G cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.3 -0.32 9.3e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs2769264 1.000 rs6684085 chr1:151357333 C/T cg18801370 chr1:151430492 POGZ -0.68 -11.45 -0.53 6.43e-26 Blood trace element (Cu levels); LIHC trans rs11039798 0.588 rs7116858 chr11:48543920 C/A cg15704280 chr7:45808275 SEPT13 0.56 6.31 0.32 8.73e-10 Axial length; LIHC cis rs8049040 0.609 rs16972805 chr16:71478249 A/G cg06353428 chr16:71660113 MARVELD3 0.67 7.29 0.37 2.15e-12 Blood protein levels; LIHC cis rs6964587 0.967 rs2040499 chr7:91809657 C/G cg17063962 chr7:91808500 NA -0.99 -20.3 -0.74 1.06e-60 Breast cancer; LIHC cis rs1707322 1.000 rs6661500 chr1:46465662 T/C cg06784218 chr1:46089804 CCDC17 0.38 6.76 0.34 6.09e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7937890 0.559 rs2575838 chr11:14498221 C/G cg02886208 chr11:14281011 SPON1 -0.44 -6.15 -0.32 2.17e-9 Mitochondrial DNA levels; LIHC cis rs6582630 0.555 rs34730221 chr12:38405140 C/T cg26384229 chr12:38710491 ALG10B -0.57 -8.23 -0.41 3.86e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs34779708 0.931 rs13377158 chr10:35370465 A/C cg04310649 chr10:35416472 CREM 0.42 5.78 0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4853036 0.951 rs35344582 chr2:70148093 C/T cg02498382 chr2:70120550 SNRNP27 -0.4 -6.25 -0.32 1.23e-9 Colorectal or endometrial cancer; LIHC cis rs6964587 0.692 rs2299233 chr7:91626953 C/T cg17063962 chr7:91808500 NA -0.63 -11.19 -0.52 5.74e-25 Breast cancer; LIHC cis rs7312933 0.510 rs61942483 chr12:42499538 T/A cg17420585 chr12:42539391 GXYLT1 -0.58 -10.2 -0.48 1.61e-21 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9368481 0.729 rs9379948 chr6:26944783 T/G cg18867708 chr6:26865862 GUSBL1 0.55 8.23 0.41 3.92e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs57502260 0.704 rs2306862 chr11:68177510 C/T cg16797656 chr11:68205561 LRP5 0.59 7.79 0.39 8.34e-14 Total body bone mineral density (age 45-60); LIHC cis rs58785573 0.504 rs13151185 chr4:38609196 G/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.55 7.81 0.39 7.13e-14 Lymphocyte percentage of white cells; LIHC cis rs34779708 0.733 rs4244997 chr10:35547254 T/C cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9733 0.596 rs72702523 chr1:150650425 G/T cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Tonsillectomy; LIHC cis rs35883536 0.566 rs12566440 chr1:101095202 A/G cg14515779 chr1:101123966 NA -0.59 -11.19 -0.52 5.49e-25 Monocyte count; LIHC cis rs10504229 1.000 rs59275611 chr8:58195191 G/A cg02290350 chr8:58132656 NA 0.47 9.18 0.44 4.15e-18 Developmental language disorder (linguistic errors); LIHC cis rs3106136 0.649 rs6532486 chr4:95300390 C/T cg11021082 chr4:95130006 SMARCAD1 0.35 5.9 0.3 8.71e-9 Capecitabine sensitivity; LIHC cis rs7224737 1.000 rs7225608 chr17:40298326 G/A cg00647820 chr17:40259828 DHX58 -0.29 -6.11 -0.31 2.67e-9 Fibrinogen levels; LIHC cis rs8072100 1.000 rs4794048 chr17:45763073 A/C cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.35 -5.78 -0.3 1.69e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg14196211 chr17:79670206 MRPL12 0.39 6.06 0.31 3.52e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs1559088 0.895 rs7259582 chr19:33593979 A/G cg17764715 chr19:33622953 WDR88 0.45 6.55 0.33 2.17e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg21248554 chr2:27665150 KRTCAP3 -0.44 -6.0 -0.31 4.96e-9 Total body bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24991452 chr6:35996059 MAPK14 0.42 6.61 0.34 1.52e-10 Cognitive function; LIHC cis rs6963495 0.818 rs73190163 chr7:105157294 G/T cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs17253792 0.822 rs117050012 chr14:56038729 G/T cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg02782426 chr3:40428986 ENTPD3 0.35 6.48 0.33 3.17e-10 Renal cell carcinoma; LIHC cis rs10861661 0.963 rs10861662 chr12:107178653 A/C cg15890332 chr12:107067104 RFX4 0.26 5.75 0.3 2.01e-8 Triglyceride levels; LIHC trans rs1994321 1.000 rs1994321 chr11:12087313 G/T cg20781238 chr11:787685 CEND1 -0.4 -6.35 -0.32 6.73e-10 Non-response to selective serotonin reuptake inhibitors and depression; LIHC cis rs6938 0.596 rs11630918 chr15:75155896 C/T cg14664628 chr15:75095509 CSK -0.5 -6.65 -0.34 1.17e-10 Breast cancer; LIHC cis rs10791097 0.653 rs11222362 chr11:130731425 T/C cg09137382 chr11:130731461 NA 0.44 6.83 0.35 3.88e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9814567 0.727 rs4435681 chr3:134344435 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.55 -8.87 -0.43 4.23e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7845219 0.544 rs4570121 chr8:95917088 C/T cg16049864 chr8:95962084 TP53INP1 -0.43 -6.43 -0.33 4.27e-10 Type 2 diabetes; LIHC cis rs4819852 0.958 rs9606204 chr22:19976510 C/A cg07821417 chr22:19972146 ARVCF 0.46 6.61 0.34 1.48e-10 Pulse pressure; LIHC trans rs3749237 0.964 rs11714957 chr3:49776178 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.64 10.1 0.48 3.53e-21 Resting heart rate; LIHC cis rs1451375 1.000 rs10247443 chr7:50620586 G/A cg14593290 chr7:50529359 DDC 0.41 6.82 0.35 4.09e-11 Malaria; LIHC cis rs2153535 0.580 rs4960413 chr6:8438466 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.88 0.39 4.36e-14 Motion sickness; LIHC cis rs6582630 0.615 rs11182380 chr12:38511735 G/T cg26384229 chr12:38710491 ALG10B -0.49 -6.87 -0.35 3.12e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs6882046 0.513 rs254780 chr5:88019747 G/C cg22951263 chr5:87985283 NA -0.39 -6.72 -0.34 7.43e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.34 0.56 3.48e-29 Prudent dietary pattern; LIHC trans rs2243480 1.000 rs1979823 chr7:65704613 G/A cg10756647 chr7:56101905 PSPH -1.04 -12.56 -0.56 5.34e-30 Diabetic kidney disease; LIHC trans rs11088226 0.709 rs55860967 chr21:33880018 G/A cg09050820 chr6:167586206 TCP10L2 0.51 6.5 0.33 2.77e-10 Gastritis; LIHC cis rs8077889 0.871 rs8065043 chr17:41900984 G/A cg26893861 chr17:41843967 DUSP3 0.95 11.14 0.52 8.8e-25 Triglycerides; LIHC cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1008375 0.898 rs4698620 chr4:17587361 C/T cg16339924 chr4:17578868 LAP3 0.45 6.24 0.32 1.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs365132 0.875 rs3923879 chr5:176355312 C/T cg16309518 chr5:176445507 NA -0.52 -9.6 -0.46 1.8e-19 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs9517320 0.534 rs4772088 chr13:99138270 T/G cg20487152 chr13:99095054 FARP1 -0.4 -6.7 -0.34 8.74e-11 Longevity; LIHC cis rs614226 1.000 rs7174 chr12:121017171 A/G cg27489772 chr12:121021490 NA 0.53 5.84 0.3 1.23e-8 Type 1 diabetes nephropathy; LIHC cis rs16958440 1.000 rs60854219 chr18:44646664 G/A cg17192377 chr18:44677553 HDHD2 0.6 6.76 0.34 5.88e-11 Sitting height ratio; LIHC cis rs8017423 0.935 rs7154695 chr14:90795705 C/G cg14092571 chr14:90743983 NA -0.41 -6.55 -0.33 2.13e-10 Mortality in heart failure; LIHC cis rs62458065 0.513 rs10268149 chr7:32575499 T/C cg06627557 chr7:32535165 LSM5;AVL9 -0.72 -7.06 -0.36 9.4e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs66573146 0.561 rs67245546 chr4:6947164 T/C cg15105060 chr4:7024189 TBC1D14 -0.78 -6.59 -0.34 1.71e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs4819052 1.000 rs733738 chr21:46666396 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.72 -9.83 -0.47 3.1e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9303401 0.625 rs10515159 chr17:56802693 G/C cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs2066819 1.000 rs77131854 chr12:56664231 C/T cg26734620 chr12:56694298 CS 1.28 10.93 0.51 4.77e-24 Psoriasis vulgaris; LIHC cis rs7191439 0.674 rs4782430 chr16:88792047 A/G cg27087555 chr16:88793112 FAM38A -1.2 -13.02 -0.58 9.8e-32 Plateletcrit; LIHC cis rs2797685 0.773 rs2301489 chr1:7837676 G/C cg04725166 chr1:7887271 PER3 -0.39 -7.0 -0.35 1.33e-11 Crohn's disease; LIHC cis rs6964587 1.000 rs4727266 chr7:91570129 C/T cg17063962 chr7:91808500 NA -1.01 -19.21 -0.72 2.67e-56 Breast cancer; LIHC cis rs35146811 0.844 rs34031156 chr7:99677917 T/A cg13334819 chr7:99746414 C7orf59 -0.56 -8.1 -0.4 9.74e-15 Coronary artery disease; LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg00091569 chr3:40428383 ENTPD3 -0.38 -6.53 -0.33 2.36e-10 Renal cell carcinoma; LIHC cis rs904251 0.523 rs1776454 chr6:37482099 C/T cg01843034 chr6:37503916 NA -0.48 -8.11 -0.4 9.22e-15 Cognitive performance; LIHC cis rs9522267 0.502 rs9522297 chr13:112234419 C/T cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs7617480 0.587 rs9311431 chr3:48848787 T/A cg07636037 chr3:49044803 WDR6 0.76 9.04 0.44 1.15e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs4073582 0.595 rs528842 chr11:66032390 G/A cg14036092 chr11:66035641 RAB1B 0.45 6.72 0.34 7.4e-11 Gout; LIHC cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg08888203 chr3:10149979 C3orf24 0.53 6.43 0.33 4.35e-10 Alzheimer's disease; LIHC cis rs2952156 0.959 rs2952151 chr17:37828496 T/C cg00129232 chr17:37814104 STARD3 -0.51 -9.41 -0.45 7.54e-19 Asthma; LIHC cis rs546131 0.642 rs523246 chr11:34845011 C/G cg06937548 chr11:34938143 PDHX;APIP 0.56 7.26 0.37 2.69e-12 Lung disease severity in cystic fibrosis; LIHC cis rs12477438 0.520 rs2632283 chr2:99776000 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs907683 0.584 rs12621188 chr2:220287892 C/G cg15015639 chr2:220282977 DES 0.36 8.46 0.42 7.95e-16 Resting heart rate; LIHC cis rs4808199 0.895 rs4808196 chr19:19476520 G/A cg03709012 chr19:19516395 GATAD2A 1.05 17.56 0.69 1.15e-49 Nonalcoholic fatty liver disease; LIHC trans rs11039798 0.511 rs717896 chr11:48375335 G/T cg15704280 chr7:45808275 SEPT13 -0.58 -6.49 -0.33 3.03e-10 Axial length; LIHC cis rs74181299 0.591 rs1894875 chr2:65363579 G/A cg05010058 chr2:65284262 CEP68 -0.35 -5.81 -0.3 1.46e-8 Pulse pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25026715 chr17:26989248 SUPT6H;SDF2 -0.48 -6.71 -0.34 8.28e-11 Pancreatic cancer; LIHC cis rs74233809 1.000 rs5011520 chr10:104697516 G/A cg03493300 chr10:104813866 CNNM2 0.46 6.09 0.31 2.98e-9 Birth weight; LIHC cis rs17270561 0.609 rs1165156 chr6:25792978 T/C cg17691542 chr6:26056736 HIST1H1C 0.44 6.01 0.31 4.75e-9 Iron status biomarkers; LIHC cis rs9513627 0.915 rs73556182 chr13:100122107 A/G cg25919922 chr13:100150906 NA -0.8 -7.07 -0.36 8.77e-12 Obesity-related traits; LIHC cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs4650994 0.525 rs2761463 chr1:178557137 T/C cg05059571 chr16:84539110 KIAA1609 0.43 7.24 0.36 3.08e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs11734570 0.581 rs4461531 chr4:38603576 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.51 7.13 0.36 5.97e-12 Inflammatory bowel disease;Crohn's disease; LIHC cis rs597539 0.690 rs552517 chr11:68625286 T/G cg04772025 chr11:68637568 NA 0.45 5.82 0.3 1.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs11792861 0.926 rs1044905 chr9:111781495 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.6 0.42 2.85e-16 Menarche (age at onset); LIHC trans rs7618501 0.633 rs2008877 chr3:50162291 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.55 -8.79 -0.43 7.33e-17 Intelligence (multi-trait analysis); LIHC cis rs853679 0.517 rs12332979 chr6:28141548 T/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.75e-10 Depression; LIHC cis rs1062177 0.951 rs2915876 chr5:151150745 C/A cg00977110 chr5:151150581 G3BP1 0.56 7.03 0.36 1.11e-11 Preschool internalizing problems; LIHC cis rs11098499 0.754 rs4107728 chr4:120253910 G/A cg09307838 chr4:120376055 NA 0.7 10.93 0.51 4.55e-24 Corneal astigmatism; LIHC cis rs7503807 1.000 rs4889775 chr17:78592287 A/G cg09596252 chr17:78655493 RPTOR 0.4 7.08 0.36 8.34e-12 Obesity; LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.97 0.31 5.88e-9 Tonsillectomy; LIHC cis rs13217239 0.646 rs7451149 chr6:27057518 A/G cg18867708 chr6:26865862 GUSBL1 -0.49 -7.46 -0.37 6.99e-13 Schizophrenia; LIHC cis rs10876993 0.890 rs1678539 chr12:58060359 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.47 -6.69 -0.34 8.89e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs10911232 0.507 rs2151669 chr1:183055398 T/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Hypertriglyceridemia; LIHC cis rs6466055 0.674 rs6967587 chr7:104744041 C/T cg04380332 chr7:105027541 SRPK2 -0.34 -6.43 -0.33 4.3e-10 Schizophrenia; LIHC cis rs55823223 0.564 rs936396 chr17:73846829 C/G cg14829360 chr17:73884958 NA -0.51 -7.67 -0.38 1.77e-13 Psoriasis; LIHC cis rs4853036 1.000 rs35002543 chr2:70091299 A/G cg02498382 chr2:70120550 SNRNP27 -0.36 -5.72 -0.3 2.26e-8 Colorectal or endometrial cancer; LIHC cis rs4319547 0.915 rs11058402 chr12:122981053 A/G cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.2 -0.41 4.94e-15 Body mass index; LIHC cis rs35110281 0.743 rs2329443 chr21:45059431 C/T cg04455712 chr21:45112962 RRP1B 0.45 7.5 0.38 5.51e-13 Mean corpuscular volume; LIHC cis rs2228479 0.850 rs1800339 chr16:89839637 C/A cg04013166 chr16:89971882 TCF25 0.52 6.62 0.34 1.35e-10 Skin colour saturation; LIHC cis rs9303401 1.000 rs6503877 chr17:56841948 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.42 6.37 0.33 6.08e-10 Cognitive test performance; LIHC trans rs9354352 0.967 rs6455062 chr6:66694131 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.6 9.72 0.47 6.91e-20 Initial pursuit acceleration in psychotic disorders; LIHC cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg23172400 chr8:95962367 TP53INP1 -0.41 -9.37 -0.45 1.03e-18 Type 2 diabetes; LIHC cis rs3806843 0.735 rs2530240 chr5:140060547 T/C cg26395211 chr5:140044315 WDR55 0.4 5.88 0.3 9.85e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs273218 1.000 rs156438 chr5:53374120 A/G ch.5.1024479R chr5:53302184 ARL15 0.67 10.78 0.5 1.59e-23 Migraine; LIHC cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.99 8.73 0.43 1.15e-16 Platelet count; LIHC trans rs916888 0.821 rs199507 chr17:44858855 A/G cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4332037 0.615 rs62435127 chr7:1884937 A/G cg23422044 chr7:1970798 MAD1L1 -0.54 -6.61 -0.34 1.49e-10 Bipolar disorder; LIHC cis rs35110281 0.659 rs73367822 chr21:45024252 C/T cg01579765 chr21:45077557 HSF2BP -0.33 -6.27 -0.32 1.06e-9 Mean corpuscular volume; LIHC cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg03264133 chr6:25882463 NA -0.45 -6.96 -0.35 1.72e-11 Height; LIHC cis rs13161895 1.000 rs17079966 chr5:179443190 G/T cg02702477 chr5:179499311 RNF130 0.74 10.14 0.48 2.7e-21 LDL cholesterol; LIHC cis rs1823913 1.000 rs4853565 chr2:192123746 C/T cg12404831 chr2:192114017 MYO1B -0.32 -6.54 -0.33 2.21e-10 Obesity-related traits; LIHC cis rs881375 0.715 rs10818482 chr9:123648085 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.39 -5.83 -0.3 1.3e-8 Rheumatoid arthritis; LIHC cis rs2380220 1.000 rs9632496 chr6:95976450 C/G cg15832292 chr6:96025679 MANEA 0.6 6.79 0.34 5.12e-11 Behavioural disinhibition (generation interaction); LIHC cis rs941408 0.515 rs4624312 chr19:2774460 T/C cg06609049 chr19:2785107 THOP1 0.81 13.66 0.59 3.3e-34 Total cholesterol levels; LIHC trans rs11098499 0.657 rs7664458 chr4:120371967 A/G cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs739401 0.572 rs7111857 chr11:3068106 A/G cg05729581 chr11:3078854 CARS 0.46 6.28 0.32 1.04e-9 Longevity; LIHC cis rs79387448 0.638 rs76255660 chr2:103091028 T/C cg09003973 chr2:102972529 NA 1.11 9.22 0.45 3.09e-18 Gut microbiota (bacterial taxa); LIHC cis rs9457247 0.765 rs1060404 chr6:167429467 A/G cg23791538 chr6:167370224 RNASET2 -0.51 -7.9 -0.39 3.74e-14 Crohn's disease; LIHC cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.77 -0.69 1.69e-50 Gut microbiome composition (summer); LIHC cis rs7512552 0.839 rs17596326 chr1:150433819 A/G cg15654264 chr1:150340011 RPRD2 0.68 11.19 0.52 5.8e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs798554 0.724 rs798498 chr7:2795882 T/G cg19717773 chr7:2847554 GNA12 -0.39 -6.33 -0.32 7.5e-10 Height; LIHC trans rs2832191 0.740 rs2832168 chr21:30463695 G/A cg14791747 chr16:20752902 THUMPD1 -0.48 -6.72 -0.34 7.47e-11 Dental caries; LIHC cis rs12744310 0.945 rs72665690 chr1:41775236 C/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs67311347 1.000 rs56992941 chr3:40472434 A/T cg18306943 chr3:40428807 ENTPD3 0.33 5.88 0.3 9.6e-9 Renal cell carcinoma; LIHC trans rs6951245 0.554 rs79367977 chr7:1152657 G/A cg13565492 chr6:43139072 SRF -0.78 -7.24 -0.36 2.9e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618501 0.501 rs35275715 chr3:49959148 A/G cg24110177 chr3:50126178 RBM5 -0.56 -8.82 -0.43 5.78e-17 Intelligence (multi-trait analysis); LIHC cis rs240110 0.539 rs6919745 chr6:101338978 T/C cg09795085 chr6:101329169 ASCC3 0.57 8.01 0.4 1.77e-14 Neuroticism; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg20295408 chr7:1910781 MAD1L1 -0.42 -6.07 -0.31 3.31e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7833986 0.501 rs2668007 chr8:56944111 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.66 6.99 0.35 1.43e-11 Height; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg11062466 chr8:58055876 NA 0.51 7.6 0.38 2.92e-13 Developmental language disorder (linguistic errors); LIHC cis rs9911578 1.000 rs172565 chr17:56808996 A/T cg12560992 chr17:57184187 TRIM37 0.98 17.88 0.7 5.79e-51 Intelligence (multi-trait analysis); LIHC cis rs6121246 0.954 rs73241710 chr20:30424956 G/A cg13852791 chr20:30311386 BCL2L1 0.85 8.9 0.43 3.42e-17 Mean corpuscular hemoglobin; LIHC cis rs2282802 0.660 rs2436390 chr5:139586501 G/A cg26211634 chr5:139558579 C5orf32 -0.37 -5.72 -0.3 2.36e-8 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04575087 chr11:46867195 CKAP5 0.47 6.39 0.33 5.54e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4332037 0.906 rs6461009 chr7:1952139 T/C cg23422044 chr7:1970798 MAD1L1 0.59 6.89 0.35 2.63e-11 Bipolar disorder; LIHC trans rs6912958 0.712 rs6908386 chr6:88354746 T/C cg23605328 chr1:201951606 RNPEP 0.38 6.07 0.31 3.35e-9 Monocyte percentage of white cells; LIHC cis rs9993613 1.000 rs2366302 chr4:73450550 T/C cg15102770 chr4:73434591 ADAMTS3 -0.38 -5.98 -0.31 5.75e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs2637266 1.000 rs7477433 chr10:78358116 C/T cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC trans rs3960554 0.808 rs59882870 chr7:75638421 G/A cg19862616 chr7:65841803 NCRNA00174 0.59 7.83 0.39 6.09e-14 Eotaxin levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03075683 chr16:11038168 CLEC16A 0.42 6.27 0.32 1.1e-9 Cognitive function; LIHC cis rs4803468 0.967 rs11083619 chr19:41913267 A/C cg14132834 chr19:41945861 ATP5SL -0.43 -6.34 -0.32 7.13e-10 Height; LIHC cis rs7959452 0.590 rs11177619 chr12:69758871 G/A cg22834771 chr12:69754056 YEATS4 -0.53 -9.34 -0.45 1.22e-18 Blood protein levels; LIHC cis rs8141529 0.871 rs5762877 chr22:29277555 G/A cg15103426 chr22:29168792 CCDC117 0.59 9.3 0.45 1.71e-18 Lymphocyte counts; LIHC cis rs2153535 0.580 rs2327061 chr6:8447231 G/C cg21535247 chr6:8435926 SLC35B3 0.61 8.03 0.4 1.61e-14 Motion sickness; LIHC cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg12463550 chr7:65579703 CRCP -0.62 -6.65 -0.34 1.18e-10 Diabetic kidney disease; LIHC cis rs1046896 0.553 rs8073413 chr17:80836005 G/A cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.46 0.37 7.27e-13 Glycated hemoglobin levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24449302 chr15:66679100 MAP2K1 -0.52 -7.82 -0.39 6.74e-14 Cognitive function; LIHC cis rs8141529 0.748 rs6005936 chr22:29289250 T/C cg15103426 chr22:29168792 CCDC117 0.59 9.59 0.46 1.86e-19 Lymphocyte counts; LIHC cis rs875971 1.000 rs7781698 chr7:65896312 A/T cg18876405 chr7:65276391 NA 0.36 6.51 0.33 2.69e-10 Aortic root size; LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg18306943 chr3:40428807 ENTPD3 0.43 7.42 0.37 9.09e-13 Renal cell carcinoma; LIHC cis rs7927592 0.763 rs10791982 chr11:68337664 T/G cg16797656 chr11:68205561 LRP5 -0.51 -9.04 -0.44 1.21e-17 Total body bone mineral density; LIHC cis rs2180341 1.000 rs9398838 chr6:127635285 C/T cg24812749 chr6:127587940 RNF146 1.07 16.09 0.66 9.4e-44 Breast cancer; LIHC cis rs3762637 1.000 rs9879508 chr3:122136480 A/G cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC cis rs8060686 0.546 rs8047978 chr16:68143598 T/G cg05110241 chr16:68378359 PRMT7 -0.5 -5.95 -0.31 6.56e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs4820539 1.000 rs3788347 chr22:23467804 G/A cg21100191 chr22:23484243 RTDR1 0.92 16.56 0.67 1.21e-45 Bone mineral density; LIHC cis rs921968 0.643 rs523396 chr2:219338789 T/G cg17980119 chr2:219472607 PLCD4 0.35 6.07 0.31 3.39e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs11671005 0.504 rs7257669 chr19:59064939 T/C cg22037779 chr5:139682734 PFDN1 -0.54 -6.48 -0.33 3.12e-10 Mean platelet volume; LIHC cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs8141529 0.748 rs7287918 chr22:29281710 G/A cg02153584 chr22:29168773 CCDC117 0.52 8.12 0.4 8.73e-15 Lymphocyte counts; LIHC cis rs244293 0.965 rs244369 chr17:53186061 C/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs9733 0.596 rs72702570 chr1:150688196 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs9393692 0.905 rs9358919 chr6:26287862 C/T cg13736514 chr6:26305472 NA -0.38 -6.28 -0.32 1.05e-9 Educational attainment; LIHC cis rs735396 0.770 rs2257764 chr12:121446446 T/A cg25281562 chr12:121454272 C12orf43 -0.36 -6.12 -0.31 2.57e-9 N-glycan levels; LIHC cis rs4407350 0.721 rs131157 chr22:44891722 A/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.39 -0.33 5.42e-10 Intelligence (multi-trait analysis); LIHC cis rs9517320 0.534 rs3825430 chr13:99129653 C/T cg07423050 chr13:99094983 FARP1 -0.51 -8.93 -0.43 2.59e-17 Longevity; LIHC cis rs1577917 0.681 rs4707211 chr6:86232710 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.45 0.33 3.91e-10 Response to antipsychotic treatment; LIHC cis rs11864453 0.611 rs9926927 chr16:72130556 G/T cg01557791 chr16:72042693 DHODH -0.43 -7.15 -0.36 5.22e-12 Fibrinogen levels; LIHC cis rs2302190 0.882 rs11650710 chr17:56583547 C/T cg12560992 chr17:57184187 TRIM37 0.72 9.09 0.44 8.09e-18 Vitamin D levels; LIHC cis rs1185460 0.565 rs657685 chr11:118912982 G/C cg01677386 chr11:118938358 VPS11 0.44 5.89 0.3 9.22e-9 Coronary artery disease; LIHC cis rs79057730 0.599 rs6951032 chr7:794092 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.83 9.15 0.44 5.17e-18 Initial pursuit acceleration; LIHC cis rs9325144 0.534 rs1973293 chr12:38679575 C/T cg26384229 chr12:38710491 ALG10B 0.48 7.3 0.37 2e-12 Morning vs. evening chronotype; LIHC cis rs1552244 0.882 rs13088350 chr3:10044626 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs6665290 0.545 rs6426584 chr1:227374949 A/T cg10327440 chr1:227177885 CDC42BPA -0.88 -13.54 -0.59 9.85e-34 Myeloid white cell count; LIHC cis rs116095464 0.558 rs62346526 chr5:220614 T/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC trans rs7618501 1.000 rs6785549 chr3:49736565 G/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.66 -0.34 1.09e-10 Intelligence (multi-trait analysis); LIHC cis rs12594515 0.967 rs71405295 chr15:45988921 T/C cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.71e-10 Waist circumference;Weight; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg12419862 chr22:24373484 LOC391322 -0.69 -10.51 -0.49 1.37e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3768617 0.706 rs6678517 chr1:183002639 A/G ch.1.3577855R chr1:183094577 LAMC1 0.51 8.13 0.4 8.13e-15 Fuchs's corneal dystrophy; LIHC cis rs3812831 0.695 rs6560935 chr13:114945867 G/A cg06611532 chr13:114900021 NA 0.38 7.11 0.36 6.85e-12 Schizophrenia; LIHC cis rs10464366 0.544 rs12701697 chr7:39182165 C/T cg18850127 chr7:39170497 POU6F2 0.45 8.07 0.4 1.2e-14 IgG glycosylation; LIHC cis rs5753618 0.561 rs1858821 chr22:31676454 T/C cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs7937682 0.889 rs551825 chr11:111480116 C/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.96 -0.51 3.76e-24 Primary sclerosing cholangitis; LIHC cis rs6545883 0.862 rs778141 chr2:61682178 A/G cg15711740 chr2:61764176 XPO1 -0.42 -5.82 -0.3 1.34e-8 Tuberculosis; LIHC cis rs3812111 0.605 rs1204845 chr6:116521190 G/A cg08036074 chr6:116424633 NT5DC1 -0.41 -6.59 -0.34 1.66e-10 Age-related macular degeneration; LIHC cis rs472402 0.580 rs11134173 chr5:6659696 C/A cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.47 -6.04 -0.31 4.06e-9 Response to amphetamines; LIHC cis rs5769765 0.908 rs9616390 chr22:50314289 G/C cg09182678 chr22:50328711 NA -0.44 -6.23 -0.32 1.33e-9 Schizophrenia; LIHC cis rs3806843 0.771 rs801174 chr5:140112712 C/T cg19875535 chr5:140030758 IK -0.41 -6.69 -0.34 9.33e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs8103278 0.507 rs7246377 chr19:46292259 G/A cg14061069 chr19:46274453 DMPK 0.69 12.68 0.57 1.85e-30 Coronary artery disease; LIHC cis rs78545713 0.536 rs11755618 chr6:26215802 C/T cg16070018 chr6:26224392 HIST1H3E -0.67 -6.53 -0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg22800045 chr5:56110881 MAP3K1 0.68 8.78 0.43 7.82e-17 Initial pursuit acceleration; LIHC cis rs7937682 0.632 rs11608193 chr11:111732215 T/C cg09085632 chr11:111637200 PPP2R1B 0.93 13.32 0.58 6.82e-33 Primary sclerosing cholangitis; LIHC cis rs1348850 0.757 rs2166554 chr2:178455824 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.56 0.53 2.67e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6582630 0.519 rs80226845 chr12:38528231 C/A cg13010199 chr12:38710504 ALG10B 0.44 5.91 0.3 8.39e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs1801251 1.000 rs6745879 chr2:233590007 A/G cg08000102 chr2:233561755 GIGYF2 0.77 11.51 0.53 3.96e-26 Coronary artery disease; LIHC cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg14393609 chr7:65229607 NA -0.42 -6.24 -0.32 1.31e-9 Aortic root size; LIHC cis rs6545883 0.894 rs2600672 chr2:61536740 A/G cg15711740 chr2:61764176 XPO1 -0.42 -5.91 -0.3 8.27e-9 Tuberculosis; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg20709868 chr19:12992305 DNASE2 0.45 6.68 0.34 9.69e-11 Migraine with aura; LIHC cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg02564969 chr6:151773285 C6orf211;RMND1 0.43 6.33 0.32 7.86e-10 Menarche (age at onset); LIHC cis rs826838 0.935 rs1160162 chr12:38959795 G/A cg26384229 chr12:38710491 ALG10B 0.92 12.44 0.56 1.42e-29 Heart rate; LIHC cis rs7772486 0.875 rs1331640 chr6:146427250 G/A cg13319975 chr6:146136371 FBXO30 -0.38 -5.96 -0.31 6.29e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs992157 0.560 rs6436047 chr2:219108913 A/C cg00012203 chr2:219082015 ARPC2 0.88 15.53 0.64 1.53e-41 Colorectal cancer; LIHC cis rs12887734 0.566 rs3742366 chr14:104198351 T/C cg08213375 chr14:104286397 PPP1R13B 0.51 8.59 0.42 3.06e-16 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs2262909 0.719 rs12461632 chr19:22245089 G/A cg05197062 chr11:11642011 GALNTL4 0.43 6.06 0.31 3.61e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs12500138 1.000 rs28407421 chr4:166169576 A/G cg25064052 chr4:166216151 KLHL2 -0.64 -5.92 -0.31 7.68e-9 Cognitive function; LIHC cis rs7635838 0.927 rs13082150 chr3:11437813 T/C cg00170343 chr3:11313890 ATG7 0.45 7.04 0.36 1.08e-11 HDL cholesterol; LIHC cis rs12477438 0.520 rs1044575 chr2:99812070 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.2 20.87 0.75 5.84e-63 Chronic sinus infection; LIHC trans rs4906332 1.000 rs3783397 chr14:103947289 A/G cg17675199 chr6:35436792 RPL10A 0.33 6.72 0.34 7.58e-11 Coronary artery disease; LIHC cis rs6815814 0.851 rs17582921 chr4:38892649 T/C cg06935464 chr4:38784597 TLR10 0.44 6.58 0.34 1.77e-10 Breast cancer; LIHC cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg18357526 chr6:26021779 HIST1H4A -0.87 -12.43 -0.56 1.65e-29 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.967 rs1794694 chr6:167404751 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC cis rs7829975 0.502 rs7820738 chr8:8702607 C/G cg06636001 chr8:8085503 FLJ10661 -0.45 -7.54 -0.38 4.21e-13 Mood instability; LIHC cis rs6840360 0.615 rs10021407 chr4:152465002 A/G cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs4820294 0.516 rs12627943 chr22:38096334 C/G cg00142150 chr22:38071001 LGALS1 0.62 8.01 0.4 1.82e-14 Fat distribution (HIV); LIHC cis rs12477438 0.765 rs1115757 chr2:99660146 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs11676348 0.846 rs7607437 chr2:219008392 A/G cg00012203 chr2:219082015 ARPC2 -0.56 -7.71 -0.38 1.43e-13 Ulcerative colitis; LIHC cis rs2204008 0.775 rs12369238 chr12:38176051 A/G cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs6570726 0.846 rs453834 chr6:145886261 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.86 0.3 1.11e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs758324 0.947 rs72793242 chr5:131242506 A/T cg06307176 chr5:131281290 NA -0.41 -5.84 -0.3 1.22e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7618501 0.521 rs2883059 chr3:49902160 C/T cg21467203 chr3:49911342 NA 0.61 11.29 0.52 2.54e-25 Intelligence (multi-trait analysis); LIHC cis rs9902453 1.000 rs12600855 chr17:28279591 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.78 0.54 4.15e-27 Coffee consumption (cups per day); LIHC trans rs1814175 0.509 rs60698301 chr11:49877672 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.95 0.35 1.82e-11 Height; LIHC cis rs6051080 1 rs6051080 chr20:25975674 A/G cg21995068 chr20:25989032 LOC100134868 -0.61 -9.81 -0.47 3.64e-20 Colorectal or endometrial cancer; LIHC cis rs6570726 0.846 rs6919684 chr6:145883801 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.88 0.3 9.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4845459 0.935 rs4845449 chr1:152591024 A/T cg20634798 chr1:152595351 LCE3A -0.31 -6.19 -0.32 1.73e-9 Psoriasis; LIHC cis rs10870270 1.000 rs11146324 chr10:133767445 A/C cg17892150 chr10:133769511 PPP2R2D -0.68 -12.84 -0.57 4.5e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs1422110 0.513 rs1363264 chr5:85450380 G/C cg01787110 chr1:109008453 NBPF6 0.31 7.8 0.39 7.42e-14 Attention function in attention deficit hyperactive disorder; LIHC cis rs6088813 1.000 rs6087705 chr20:34001250 C/T cg14752227 chr20:34000481 UQCC -0.4 -5.74 -0.3 2.1e-8 Height; LIHC cis rs244293 0.931 rs2628323 chr17:53203097 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.58 -0.38 3.24e-13 Menarche (age at onset); LIHC trans rs61931739 0.500 rs11053243 chr12:34514155 T/C cg26384229 chr12:38710491 ALG10B 0.63 8.12 0.4 8.29e-15 Morning vs. evening chronotype; LIHC cis rs8180040 0.726 rs4682844 chr3:46982737 T/C cg27129171 chr3:47204927 SETD2 -0.64 -10.74 -0.5 2.22e-23 Colorectal cancer; LIHC cis rs4728302 1.000 rs4728302 chr7:133630463 C/T cg10665199 chr7:133106180 EXOC4 -0.35 -5.89 -0.3 9.4e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs6693567 0.565 rs834238 chr1:150366469 G/T cg15654264 chr1:150340011 RPRD2 0.49 8.23 0.41 4.1e-15 Migraine; LIHC cis rs2075371 1.000 rs378358 chr7:133970628 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.71 0.38 1.39e-13 Mean platelet volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07489123 chr19:1812466 ATP8B3 0.42 6.06 0.31 3.56e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3741404 0.757 rs2282492 chr11:63918589 A/G cg24431193 chr11:63883947 FLRT1;MACROD1 -0.38 -5.81 -0.3 1.4e-8 Platelet count; LIHC cis rs10911251 0.508 rs729672 chr1:183109236 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.47 0.49 1.93e-22 Colorectal cancer; LIHC cis rs9733 0.544 rs2867302 chr1:150653650 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Tonsillectomy; LIHC cis rs2073300 0.609 rs1936011 chr20:23341912 G/C cg16736954 chr20:23401023 NAPB 0.71 8.42 0.41 1.06e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2073499 1.000 rs739431 chr3:50255305 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.48 5.91 0.3 8.47e-9 Schizophrenia; LIHC cis rs921968 0.565 rs6436073 chr2:219618237 A/C cg02985541 chr2:219472218 PLCD4 -0.36 -6.36 -0.33 6.34e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg06634786 chr22:41940651 POLR3H -0.79 -8.65 -0.42 2.06e-16 Vitiligo; LIHC cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg06453172 chr10:134556979 INPP5A -0.62 -7.77 -0.39 9.51e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9467773 0.565 rs4343916 chr6:26522675 A/T cg11502198 chr6:26597334 ABT1 0.6 7.98 0.4 2.23e-14 Intelligence (multi-trait analysis); LIHC cis rs7914558 0.869 rs10883842 chr10:104941589 C/T cg15744005 chr10:104629667 AS3MT -0.38 -8.65 -0.42 2.09e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7635838 0.619 rs347616 chr3:11277927 G/A cg00170343 chr3:11313890 ATG7 0.53 8.11 0.4 9.15e-15 HDL cholesterol; LIHC cis rs12477438 0.798 rs10167015 chr2:99570707 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.79 -10.23 -0.48 1.36e-21 Chronic sinus infection; LIHC cis rs4900538 0.855 rs1210074 chr14:102889098 G/A cg18135206 chr14:102964638 TECPR2 -0.71 -11.04 -0.51 1.89e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs116095464 0.542 rs28650039 chr5:273954 C/A cg22857025 chr5:266934 NA -1.48 -18.36 -0.7 7.27e-53 Breast cancer; LIHC cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg10862848 chr6:42927986 GNMT -0.27 -6.29 -0.32 9.46e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs72781680 0.716 rs6731314 chr2:24048338 C/T cg08917208 chr2:24149416 ATAD2B -0.62 -6.44 -0.33 4.09e-10 Lymphocyte counts; LIHC cis rs9457247 1.000 rs2769352 chr6:167378619 A/G cg07741184 chr6:167504864 NA -0.29 -6.7 -0.34 8.84e-11 Crohn's disease; LIHC cis rs3020736 0.500 rs8138678 chr22:42516229 A/G cg15557168 chr22:42548783 NA 0.41 6.5 0.33 2.91e-10 Autism spectrum disorder or schizophrenia; LIHC cis rs9308433 0.529 rs11800749 chr1:214499754 A/G cg06198575 chr1:214491504 SMYD2 -0.54 -6.01 -0.31 4.71e-9 IgG glycosylation; LIHC cis rs10504229 0.906 rs7846666 chr8:58172302 T/C cg02290350 chr8:58132656 NA 0.41 8.7 0.43 1.43e-16 Developmental language disorder (linguistic errors); LIHC cis rs17021463 0.966 rs1565062 chr4:95183000 G/A cg11021082 chr4:95130006 SMARCAD1 -0.5 -9.29 -0.45 1.88e-18 Testicular germ cell tumor; LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg08677398 chr8:58056175 NA 0.39 6.06 0.31 3.68e-9 Developmental language disorder (linguistic errors); LIHC trans rs4714291 0.832 rs7764688 chr6:40115442 G/T cg02267698 chr19:7991119 CTXN1 -0.4 -6.63 -0.34 1.3100000000000001e-10 Strep throat; LIHC cis rs9309473 0.607 rs6720094 chr2:73588076 A/G cg20560298 chr2:73613845 ALMS1 -0.46 -7.38 -0.37 1.2e-12 Metabolite levels; LIHC cis rs2806561 0.754 rs648322 chr1:23294839 C/T cg19743168 chr1:23544995 NA 0.36 6.66 0.34 1.11e-10 Height; LIHC cis rs6964587 1.000 rs7802668 chr7:91648939 A/G cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs3008870 1.000 rs1925408 chr1:67365034 C/T cg02640540 chr1:67518911 SLC35D1 0.44 6.08 0.31 3.12e-9 Lymphocyte percentage of white cells; LIHC trans rs2243480 1.000 rs316325 chr7:65609518 G/A cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs12464559 0.649 rs6708645 chr2:152620387 A/T cg01189475 chr2:152685088 ARL5A 0.63 7.46 0.37 7.1e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC trans rs9951602 0.512 rs9958376 chr18:76655167 G/T cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC trans rs1814175 0.645 rs1608632 chr11:49967148 C/T cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs798554 0.686 rs2527690 chr7:2854250 C/T cg19717773 chr7:2847554 GNA12 -0.43 -7.63 -0.38 2.36e-13 Height; LIHC cis rs2455799 0.573 rs924753 chr3:15706124 C/T cg16303742 chr3:15540471 COLQ -0.39 -6.78 -0.34 5.3e-11 Mean platelet volume; LIHC cis rs1355223 0.902 rs11607035 chr11:34718911 G/A cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.38 -0.33 5.6e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg00684032 chr4:1343700 KIAA1530 0.51 7.46 0.37 7.3e-13 Obesity-related traits; LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs7727544 0.904 rs58835386 chr5:131600559 A/G cg24060327 chr5:131705240 SLC22A5 -0.52 -5.83 -0.3 1.25e-8 Blood metabolite levels; LIHC cis rs7927592 0.871 rs113020558 chr11:68296832 G/A cg01657329 chr11:68192670 LRP5 -0.46 -6.05 -0.31 3.88e-9 Total body bone mineral density; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs1267303 0.642 rs2404611 chr1:46997127 C/G cg25110126 chr1:46999211 NA 0.44 6.16 0.32 2.06e-9 Monobrow; LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg11494091 chr17:61959527 GH2 0.36 6.03 0.31 4.25e-9 Height; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg16132339 chr22:24313637 DDTL;DDT 0.82 17.02 0.68 1.78e-47 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg00091569 chr3:40428383 ENTPD3 0.38 6.49 0.33 2.95e-10 Renal cell carcinoma; LIHC cis rs34779708 0.733 rs7914468 chr10:35548071 G/A cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2361710 0.668 rs4889830 chr17:78114528 G/A cg09238746 chr17:78121135 EIF4A3 -0.53 -8.21 -0.41 4.46e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; LIHC cis rs703842 0.642 rs10876994 chr12:58064737 A/C cg15848620 chr12:58087721 OS9 0.52 6.55 0.33 2.15e-10 Multiple sclerosis; LIHC trans rs3780486 1.000 rs10813951 chr9:33128021 C/T cg04842962 chr6:43655489 MRPS18A -0.96 -17.64 -0.69 5.3e-50 IgG glycosylation; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg19568834 chr20:34252926 CPNE1;RBM12 -0.4 -6.05 -0.31 3.79e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs853679 0.517 rs4711164 chr6:28115156 C/T cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07730007 chr12:107377277 MTERFD3 0.44 6.05 0.31 3.84e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg05590025 chr7:65112418 INTS4L2 -0.45 -6.89 -0.35 2.62e-11 Calcium levels; LIHC cis rs8017423 0.967 rs57793584 chr14:90714833 G/A cg14092571 chr14:90743983 NA -0.37 -5.88 -0.3 9.67e-9 Mortality in heart failure; LIHC cis rs986417 0.818 rs1254325 chr14:60909689 A/G cg27398547 chr14:60952738 C14orf39 -0.7 -8.45 -0.42 8.5e-16 Gut microbiota (bacterial taxa); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13286318 chr8:57906058 IMPAD1 0.49 6.73 0.34 7.05e-11 Lung function (FEV1/FVC); LIHC cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg24642844 chr7:1081250 C7orf50 -0.92 -8.96 -0.44 2.13e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6430585 0.583 rs3769008 chr2:136586183 C/T cg07169764 chr2:136633963 MCM6 1.33 20.83 0.75 8.23e-63 Corneal structure; LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs67311347 0.635 rs73071706 chr3:40288190 C/A cg18306943 chr3:40428807 ENTPD3 0.4 6.81 0.35 4.42e-11 Renal cell carcinoma; LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg23782820 chr8:58130467 NA 0.34 5.87 0.3 1.04e-8 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04633058 chr17:48474099 LRRC59 0.49 7.42 0.37 9.52e-13 Pancreatic cancer; LIHC cis rs2075371 0.897 rs1646702 chr7:134000177 C/G cg20476274 chr7:133979776 SLC35B4 0.74 12.16 0.55 1.65e-28 Mean platelet volume; LIHC cis rs61677309 1.000 rs66832804 chr11:118157049 T/A cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs2274273 0.624 rs10141396 chr14:55816925 A/C cg01864836 chr14:55583639 NA -0.36 -5.86 -0.3 1.07e-8 Protein biomarker; LIHC cis rs2153535 0.580 rs986060 chr6:8465428 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs10870270 1.000 rs72636963 chr10:133771271 C/T cg26149184 chr10:133730230 NA 0.47 7.5 0.38 5.69e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1580019 0.563 rs34201720 chr7:32568935 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.12 25.1 0.81 1.47e-79 Cognitive ability; LIHC trans rs4650994 0.544 rs2761469 chr1:178590638 A/C cg05059571 chr16:84539110 KIAA1609 0.41 6.95 0.35 1.89e-11 HDL cholesterol levels;HDL cholesterol; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg01630199 chr7:66369076 NA 0.41 6.1 0.31 2.8e-9 Bilirubin levels; LIHC trans rs1814175 0.647 rs61306292 chr11:49856040 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.83 0.35 3.95e-11 Height; LIHC cis rs8180040 0.620 rs2305635 chr3:47043622 G/A cg27129171 chr3:47204927 SETD2 -0.55 -9.1 -0.44 7.81e-18 Colorectal cancer; LIHC cis rs7552167 0.852 rs10794647 chr1:24509133 C/T cg01960748 chr1:24522592 NA -0.76 -9.07 -0.44 9.33e-18 Psoriasis vulgaris; LIHC cis rs911555 0.511 rs2296483 chr14:104029792 G/A cg24130564 chr14:104152367 KLC1 -0.62 -11.22 -0.52 4.36e-25 Intelligence (multi-trait analysis); LIHC cis rs1152591 0.505 rs1152593 chr14:64675895 C/T cg21174375 chr14:64681225 SYNE2 0.37 5.9 0.3 8.68e-9 Atrial fibrillation; LIHC cis rs7726839 0.574 rs12517345 chr5:628294 G/A cg09021430 chr5:549028 NA -0.42 -8.46 -0.42 7.81e-16 Obesity-related traits; LIHC cis rs11690935 0.632 rs62183783 chr2:172865775 A/G cg13550731 chr2:172543902 DYNC1I2 0.44 6.63 0.34 1.27e-10 Schizophrenia; LIHC cis rs9733 0.628 rs11807409 chr1:150683423 C/T cg18016565 chr1:150552671 MCL1 0.58 11.49 0.53 4.67e-26 Tonsillectomy; LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.91 -0.3 8.35e-9 Total body bone mineral density; LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg00091569 chr3:40428383 ENTPD3 0.4 6.88 0.35 2.9e-11 Renal cell carcinoma; LIHC cis rs3736485 0.966 rs7170444 chr15:51890500 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.37 -0.33 5.94e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7116495 0.609 rs1894004 chr11:71759817 G/A cg26138937 chr11:71823887 C11orf51 -1.34 -10.79 -0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC trans rs2727020 0.573 rs7925419 chr11:49231859 C/T cg15704280 chr7:45808275 SEPT13 -0.61 -9.93 -0.47 1.42e-20 Coronary artery disease; LIHC cis rs2016586 0.802 rs5999975 chr22:36115911 G/A cg26342177 chr22:36113512 APOL5 -0.39 -6.57 -0.33 1.82e-10 Body mass index; LIHC cis rs7582180 0.663 rs6542944 chr2:100988038 T/C cg14675211 chr2:100938903 LONRF2 0.56 8.26 0.41 3.32e-15 Intelligence (multi-trait analysis); LIHC cis rs4727027 0.933 rs13225884 chr7:148857795 A/G cg23583168 chr7:148888333 NA -0.72 -10.27 -0.49 9.23e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs17270561 0.636 rs1185977 chr6:25829054 A/G cg17691542 chr6:26056736 HIST1H1C 0.42 5.82 0.3 1.34e-8 Iron status biomarkers; LIHC cis rs6558530 0.692 rs6558522 chr8:1702370 C/G cg24391279 chr8:1708526 NA 0.33 5.99 0.31 5.2e-9 Systolic blood pressure; LIHC trans rs6951245 0.554 rs11544331 chr7:1131411 C/T cg13565492 chr6:43139072 SRF -0.77 -7.06 -0.36 9.29e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2952156 0.920 rs2517954 chr17:37843550 T/C cg00129232 chr17:37814104 STARD3 -0.53 -9.68 -0.46 9.32e-20 Asthma; LIHC trans rs11098499 0.954 rs11734241 chr4:120416872 A/G cg25214090 chr10:38739885 LOC399744 0.58 9.43 0.45 6.45e-19 Corneal astigmatism; LIHC cis rs611744 0.647 rs4735053 chr8:109260776 A/G cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs7911264 0.572 rs7071912 chr10:94416229 T/G cg25506282 chr10:94462361 NA 0.38 6.39 0.33 5.33e-10 Inflammatory bowel disease; LIHC cis rs4819052 0.819 rs8134084 chr21:46693295 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.26 0.41 3.32e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg24879335 chr3:133465180 TF 0.26 5.84 0.3 1.19e-8 Iron status biomarkers; LIHC cis rs1538970 0.924 rs11211108 chr1:45891152 C/T cg05343316 chr1:45956843 TESK2 0.57 8.37 0.41 1.49e-15 Platelet count; LIHC cis rs7520050 0.897 rs4440807 chr1:46470878 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.0 0.31 4.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6502050 0.835 rs9891962 chr17:80153594 T/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.91 -0.3 8.14e-9 Life satisfaction; LIHC cis rs2279817 0.780 rs77072467 chr1:17979675 T/C cg21791023 chr1:18019539 ARHGEF10L -0.66 -7.14 -0.36 5.8e-12 Neuroticism; LIHC cis rs1577917 0.771 rs4351223 chr6:86237797 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 8.11 0.4 9.35e-15 Response to antipsychotic treatment; LIHC cis rs3809566 0.963 rs3809565 chr15:63333619 A/G cg05771511 chr15:63340396 TPM1 0.51 7.46 0.37 7.16e-13 Platelet count; LIHC cis rs7582180 0.764 rs12615466 chr2:100924065 C/A cg14675211 chr2:100938903 LONRF2 0.51 8.05 0.4 1.42e-14 Intelligence (multi-trait analysis); LIHC cis rs910316 0.935 rs175076 chr14:75505486 A/G cg08847533 chr14:75593920 NEK9 -0.89 -19.31 -0.72 1.07e-56 Height; LIHC cis rs7772486 0.622 rs1292333 chr6:145982344 C/T cg13319975 chr6:146136371 FBXO30 0.36 5.79 0.3 1.61e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs172166 0.611 rs203883 chr6:28078356 A/G cg16479474 chr6:28041457 NA 0.39 6.52 0.33 2.57e-10 Cardiac Troponin-T levels; LIHC cis rs3790645 1.000 rs3127013 chr1:26891360 T/G cg23229016 chr1:26872525 RPS6KA1 0.23 5.73 0.3 2.26e-8 Glucose homeostasis traits; LIHC cis rs875971 0.862 rs7786892 chr7:65628876 G/A cg11764359 chr7:65958608 NA -0.84 -14.15 -0.61 4.2500000000000003e-36 Aortic root size; LIHC cis rs8078723 1.000 rs4794823 chr17:38166265 A/T cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.14 -0.44 5.58e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs853679 0.517 rs55747925 chr6:28044337 T/C cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs1211375 0.628 rs3859141 chr16:245079 T/C cg00126636 chr16:237282 NA -0.41 -7.0 -0.35 1.39e-11 Hematology traits;Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2153535 0.541 rs9392222 chr6:8467649 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg03060546 chr3:49711283 APEH 0.4 6.05 0.31 3.86e-9 Menarche (age at onset); LIHC cis rs7246865 0.954 rs1060367 chr19:17215202 G/A cg16202187 chr19:17186497 HAUS8;MYO9B 0.41 6.26 0.32 1.15e-9 Reticulocyte fraction of red cells; LIHC cis rs7131987 0.868 rs10771508 chr12:29414211 G/A cg21522988 chr12:29376872 FAR2 0.3 6.86 0.35 3.28e-11 QT interval; LIHC trans rs877282 0.838 rs11253373 chr10:774857 A/G cg22713356 chr15:30763199 NA 1.37 12.47 0.56 1.08e-29 Uric acid levels; LIHC cis rs147649347 1 rs147649347 chr2:24210076 GATAA/G cg08917208 chr2:24149416 ATAD2B 0.9 8.01 0.4 1.83e-14 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7520050 0.778 rs3013597 chr1:46128356 C/A cg24296786 chr1:45957014 TESK2 -0.39 -5.88 -0.3 9.77e-9 Red blood cell count;Reticulocyte count; LIHC cis rs3806843 0.900 rs2261651 chr5:140136804 A/C cg26395211 chr5:140044315 WDR55 0.41 6.09 0.31 2.99e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs11014306 0.841 rs11014309 chr10:25224755 C/A cg06869505 chr1:15527517 TMEM51 0.34 6.04 0.31 4.02e-9 Metabolite levels (Pyroglutamine); LIHC cis rs249954 0.512 rs249856 chr16:23658976 G/A cg09867953 chr16:23706666 ERN2 0.38 6.37 0.33 6.15e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs782590 0.967 rs4672054 chr2:55773093 C/A cg03859395 chr2:55845619 SMEK2 0.9 15.58 0.64 9.6e-42 Metabolic syndrome; LIHC cis rs8005677 0.962 rs10130756 chr14:23396600 C/G cg25600027 chr14:23388339 RBM23 -0.41 -6.02 -0.31 4.4e-9 Cognitive ability (multi-trait analysis); LIHC cis rs4650994 0.550 rs12047530 chr1:178543407 A/G cg05350800 chr1:178550844 NA -0.35 -7.64 -0.38 2.26e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs644799 0.710 rs666398 chr11:95551136 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.76 13.11 0.58 4.33e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.97 12.39 0.56 2.21e-29 Alzheimer's disease; LIHC trans rs9951602 0.512 rs7234283 chr18:76640552 T/G cg02800362 chr5:177631904 HNRNPAB 0.64 10.11 0.48 3.27e-21 Obesity-related traits; LIHC cis rs7208859 0.673 rs2433 chr17:29226228 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.0 0.4 1.95e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8180040 0.739 rs66539935 chr3:47025327 C/T cg16586182 chr3:47516702 SCAP 0.45 7.87 0.39 4.8e-14 Colorectal cancer; LIHC cis rs3823572 0.548 rs2971981 chr7:133651555 T/C cg03336402 chr7:133662267 EXOC4 -0.48 -5.85 -0.3 1.15e-8 Intelligence (multi-trait analysis); LIHC cis rs7727544 0.735 rs274568 chr5:131713578 C/T cg07395648 chr5:131743802 NA 0.32 6.69 0.34 9.1e-11 Blood metabolite levels; LIHC cis rs9296092 0.538 rs62405942 chr6:33517346 G/A cg13560919 chr6:33536144 NA -0.38 -6.36 -0.33 6.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs1878931 0.696 rs35984213 chr16:3451030 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 23.39 0.78 6.36e-73 Body mass index (adult); LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg14828511 chr1:107599125 PRMT6 -0.42 -6.01 -0.31 4.79e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7552404 0.727 rs7547508 chr1:76327958 A/G cg03433033 chr1:76189801 ACADM -0.54 -6.87 -0.35 3.06e-11 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18716194 chr12:110872950 ARPC3 0.47 6.94 0.35 1.98e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs72781680 1.000 rs12614452 chr2:24194608 C/T cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs1401999 1.000 rs6443927 chr3:183718864 A/G cg05044414 chr3:183734942 ABCC5 0.34 5.99 0.31 5.23e-9 Anterior chamber depth; LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg18252515 chr7:66147081 NA -1.26 -16.36 -0.66 7.9e-45 Diabetic kidney disease; LIHC cis rs35306767 0.903 rs35370435 chr10:898205 T/C cg26597838 chr10:835615 NA 1.47 16.88 0.67 6.43e-47 Eosinophil percentage of granulocytes; LIHC cis rs8062405 1.000 rs12443881 chr16:28841777 C/T cg00204512 chr16:28754710 NA 0.37 6.77 0.34 5.79e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs227584 0.663 rs3180912 chr17:42259463 A/G cg19774624 chr17:42201019 HDAC5 -0.67 -10.09 -0.48 3.96e-21 Bone mineral density (hip);Bone mineral density; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs17125944 0.686 rs4901305 chr14:53364271 C/T cg00686598 chr14:53173677 PSMC6 -0.81 -8.99 -0.44 1.66e-17 Alzheimer's disease (late onset); LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg08219700 chr8:58056026 NA 0.52 7.16 0.36 4.94e-12 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.679 rs1639066 chr7:2892972 A/G cg04166393 chr7:2884313 GNA12 0.53 8.56 0.42 3.84e-16 Height; LIHC cis rs10504073 0.584 rs17642664 chr8:49942945 A/G cg00325661 chr8:49890786 NA 0.34 7.75 0.39 1.03e-13 Blood metabolite ratios; LIHC cis rs6754311 0.509 rs3820794 chr2:136505546 C/T cg15123519 chr2:136567270 LCT 0.35 6.67 0.34 1.05e-10 Mosquito bite size; LIHC cis rs926392 0.640 rs62202616 chr20:37692775 G/C cg16355469 chr20:37678765 NA 0.49 7.31 0.37 1.87e-12 Dialysis-related mortality; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14802876 chr6:34217098 C6orf1 -0.38 -6.13 -0.31 2.38e-9 Pancreatic cancer; LIHC cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg11766577 chr21:47581405 C21orf56 -0.45 -7.55 -0.38 4.01e-13 Testicular germ cell tumor; LIHC cis rs66486766 1 rs66486766 chr15:84806060 G/A cg17507749 chr15:85114479 UBE2QP1 0.77 7.91 0.39 3.56e-14 Bipolar disorder lithium response (categorical) or schizophrenia; LIHC cis rs7481584 0.581 rs420127 chr11:3077990 C/T cg25174290 chr11:3078921 CARS -0.44 -6.5 -0.33 2.79e-10 Calcium levels; LIHC cis rs8177253 1.000 rs3811647 chr3:133484029 G/A cg12373951 chr3:133503437 NA 0.69 12.31 0.55 4.59e-29 Iron status biomarkers; LIHC cis rs9522267 0.535 rs11069897 chr13:112231319 A/G cg10483660 chr13:112241077 NA -0.22 -5.88 -0.3 9.86e-9 Hepatitis; LIHC cis rs4927850 0.709 rs6783079 chr3:195652708 T/C cg01181863 chr3:195395398 SDHAP2 -0.83 -8.77 -0.43 8.65e-17 Pancreatic cancer; LIHC cis rs6429082 0.818 rs704706 chr1:235614378 G/A cg26050004 chr1:235667680 B3GALNT2 0.47 7.15 0.36 5.39e-12 Adiposity; LIHC cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg20607798 chr8:58055168 NA 0.6 7.16 0.36 4.99e-12 Developmental language disorder (linguistic errors); LIHC cis rs116095464 0.614 rs10061564 chr5:271329 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs36051895 0.530 rs10114531 chr9:5229116 A/G cg02405213 chr9:5042618 JAK2 -0.6 -9.37 -0.45 1.01e-18 Pediatric autoimmune diseases; LIHC cis rs477692 0.905 rs514963 chr10:131419707 C/T cg05714579 chr10:131428358 MGMT 0.46 7.73 0.39 1.24e-13 Response to temozolomide; LIHC cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.33 0.41 1.99e-15 Platelet count; LIHC cis rs10540 1.000 rs78520676 chr11:517173 G/A cg03576123 chr11:487126 PTDSS2 -1.03 -7.25 -0.36 2.89e-12 Body mass index; LIHC cis rs9611565 0.592 rs5758427 chr22:42099688 A/G cg03806693 chr22:41940476 POLR3H 0.83 9.38 0.45 9.11e-19 Vitiligo; LIHC cis rs909341 0.859 rs2258056 chr20:62328453 T/C cg03999872 chr20:62272968 STMN3 -0.46 -6.78 -0.34 5.22e-11 Atopic dermatitis; LIHC trans rs4650994 0.544 rs10798613 chr1:178500022 C/T cg05059571 chr16:84539110 KIAA1609 -0.45 -7.63 -0.38 2.31e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7208859 0.673 rs56846352 chr17:29119188 C/T cg13385521 chr17:29058706 SUZ12P 0.81 8.22 0.41 4.36e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7512552 0.839 rs11587116 chr1:150451898 A/T cg15654264 chr1:150340011 RPRD2 0.66 10.96 0.51 3.65e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs6456156 0.716 rs6905876 chr6:167521562 C/T cg07741184 chr6:167504864 NA 0.24 5.77 0.3 1.76e-8 Primary biliary cholangitis; LIHC cis rs6964587 1.000 rs34043009 chr7:91578447 T/C cg17063962 chr7:91808500 NA -1.01 -19.24 -0.72 1.97e-56 Breast cancer; LIHC trans rs1499614 1.000 rs1882655 chr7:66147057 T/C cg07424592 chr7:64974309 NA -0.77 -8.94 -0.44 2.49e-17 Gout; LIHC cis rs4820294 0.669 rs732857 chr22:38060850 C/T cg10587741 chr22:38071170 LGALS1 0.47 8.48 0.42 6.84e-16 Fat distribution (HIV); LIHC cis rs6570726 0.791 rs4896820 chr6:145894957 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.74 0.3 2.1e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg14737905 chr2:128186178 PROC 0.46 6.86 0.35 3.21e-11 Immature fraction of reticulocytes; LIHC cis rs6940638 0.531 rs12211984 chr6:26986054 G/C cg18867708 chr6:26865862 GUSBL1 0.52 8.1 0.4 9.8e-15 Intelligence (multi-trait analysis); LIHC trans rs10491431 0.866 rs10461715 chr5:36002012 C/T cg26557896 chr1:77165565 NA -0.4 -6.59 -0.34 1.69e-10 Blood metabolite levels; LIHC cis rs2832191 0.692 rs2776240 chr21:30310639 C/T cg24692254 chr21:30365293 RNF160 0.83 13.78 0.6 1.19e-34 Dental caries; LIHC cis rs1371867 0.846 rs1788206 chr8:101306966 A/G cg06636551 chr8:101224915 SPAG1 -0.5 -9.06 -0.44 1.02e-17 Atrioventricular conduction; LIHC cis rs11583043 1.000 rs17123612 chr1:101476814 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.58 7.77 0.39 9.01e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1801251 1.000 rs11555646 chr2:233599904 A/C cg25237894 chr2:233734115 C2orf82 0.58 11.25 0.52 3.32e-25 Coronary artery disease; LIHC cis rs11229555 0.645 rs10896775 chr11:58175989 A/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg16049864 chr8:95962084 TP53INP1 -0.63 -11.79 -0.54 3.69e-27 Type 2 diabetes; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01973725 chr5:80608537 RNU5E;RNU5D;ZCCHC9 0.38 6.08 0.31 3.27e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.1 0.44 7.68e-18 Bipolar disorder; LIHC cis rs477692 0.935 rs557158 chr10:131420534 C/T cg05714579 chr10:131428358 MGMT 0.44 7.32 0.37 1.82e-12 Response to temozolomide; LIHC cis rs11792861 0.851 rs17552292 chr9:111891954 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.6 8.42 0.41 1.05e-15 Menarche (age at onset); LIHC cis rs7487075 0.619 rs12314541 chr12:46794766 T/C cg23829395 chr12:46796953 NA 0.35 6.28 0.32 1.06e-9 Itch intensity from mosquito bite; LIHC cis rs12142240 0.621 rs13374968 chr1:46843908 T/G cg00530320 chr1:46809349 NSUN4 0.53 5.81 0.3 1.45e-8 Menopause (age at onset); LIHC cis rs3768617 0.510 rs3768629 chr1:183074582 T/C ch.1.3577855R chr1:183094577 LAMC1 0.63 11.02 0.51 2.36e-24 Fuchs's corneal dystrophy; LIHC cis rs7572733 0.534 rs700670 chr2:198687284 T/C cg03934865 chr2:198174659 NA 0.45 6.47 0.33 3.42e-10 Dermatomyositis; LIHC cis rs2522056 0.935 rs1981524 chr5:131756506 C/T cg24060327 chr5:131705240 SLC22A5 0.6 7.96 0.4 2.6e-14 Lymphocyte counts;Fibrinogen; LIHC cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg03517284 chr6:25882590 NA 0.89 12.44 0.56 1.51e-29 Blood metabolite levels; LIHC cis rs600806 0.778 rs491285 chr1:110019002 C/T cg08911820 chr1:110026001 ATXN7L2 0.56 6.91 0.35 2.45e-11 Intelligence (multi-trait analysis); LIHC trans rs10492096 1.000 rs10492096 chr12:6580582 A/G cg14169308 chr2:86850884 RNF103 0.63 6.08 0.31 3.24e-9 Hip geometry; LIHC cis rs4927850 0.752 rs7618864 chr3:195749561 G/A cg12923728 chr3:195709715 SDHAP1 -0.7 -10.32 -0.49 6.71e-22 Pancreatic cancer; LIHC cis rs4834770 0.792 rs7676969 chr4:120173724 C/T cg09307838 chr4:120376055 NA 0.41 5.86 0.3 1.08e-8 Blood protein levels; LIHC cis rs7044106 0.791 rs735110 chr9:123488940 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.77 12.65 0.56 2.36e-30 Hip circumference adjusted for BMI; LIHC cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg06634786 chr22:41940651 POLR3H 0.83 9.1 0.44 7.39e-18 Vitiligo; LIHC cis rs10847980 0.590 rs78462864 chr12:123365867 C/T cg25930673 chr12:123319894 HIP1R 1.14 11.54 0.53 3.14e-26 Adiponectin levels; LIHC cis rs4589502 1.000 rs12440279 chr15:67133339 G/A cg09911534 chr15:67153556 NA -0.48 -5.94 -0.31 7.08e-9 Lung cancer (smoking interaction); LIHC cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg24531977 chr5:56204891 C5orf35 -0.68 -9.82 -0.47 3.24e-20 Initial pursuit acceleration; LIHC cis rs9911578 1.000 rs999431 chr17:56854441 A/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.68 -0.43 1.61e-16 Intelligence (multi-trait analysis); LIHC cis rs7824557 0.591 rs2736283 chr8:11225910 A/G cg21775007 chr8:11205619 TDH -0.61 -9.45 -0.46 5.37e-19 Retinal vascular caliber; LIHC cis rs2073300 1.000 rs6048834 chr20:23462213 C/T cg12062639 chr20:23401060 NAPB 0.78 9.81 0.47 3.62e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2066819 1.000 rs2291361 chr12:56717805 G/A cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg24675658 chr1:53192096 ZYG11B 0.58 9.13 0.44 6.03e-18 Monocyte count; LIHC cis rs11190604 1.000 rs10883513 chr10:102316964 A/G cg07080220 chr10:102295463 HIF1AN 0.57 7.49 0.38 6.12e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs67478160 0.575 rs8014294 chr14:104322983 A/G cg01849466 chr14:104193079 ZFYVE21 -0.53 -8.72 -0.43 1.27e-16 Schizophrenia; LIHC cis rs12594515 1.000 rs6493168 chr15:45986811 A/C cg19682013 chr15:45996608 NA 0.41 7.25 0.37 2.78e-12 Waist circumference;Weight; LIHC cis rs17253792 0.822 rs28831725 chr14:56087569 C/T cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs1801251 1.000 rs6714245 chr2:233580505 T/C cg25237894 chr2:233734115 C2orf82 0.56 10.97 0.51 3.3e-24 Coronary artery disease; LIHC cis rs2204008 0.837 rs34381557 chr12:38181983 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs2153535 0.580 rs9406163 chr6:8466642 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs754466 0.606 rs12356375 chr10:79594514 C/A cg17075019 chr10:79541650 NA -0.79 -12.28 -0.55 6e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2540917 0.904 rs2668729 chr2:60608383 G/A cg00543073 chr2:60773386 BCL11A -0.29 -5.79 -0.3 1.6e-8 Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12315590 chr3:128997497 C3orf37 0.51 7.4 0.37 1.1e-12 Pancreatic cancer; LIHC cis rs6456156 0.819 rs7765739 chr6:167518472 C/T cg07741184 chr6:167504864 NA 0.26 6.28 0.32 1.03e-9 Primary biliary cholangitis; LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg07133347 chr1:107600762 PRMT6 -0.41 -6.19 -0.32 1.72e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs986417 0.901 rs1955692 chr14:61008408 C/A cg27398547 chr14:60952738 C14orf39 0.74 8.04 0.4 1.5e-14 Gut microbiota (bacterial taxa); LIHC cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg20295408 chr7:1910781 MAD1L1 -0.52 -7.63 -0.38 2.29e-13 Bipolar disorder and schizophrenia; LIHC cis rs4975709 0.589 rs1466607 chr5:1864856 A/G cg14773178 chr5:1868261 NA 0.26 6.72 0.34 7.55e-11 Cardiovascular disease risk factors; LIHC trans rs1436334 1.000 rs6783422 chr3:104548890 A/G cg27425383 chr3:125776273 SLC41A3 -0.34 -6.41 -0.33 4.75e-10 Initial pursuit acceleration; LIHC cis rs6545883 0.894 rs778144 chr2:61583128 A/C cg14146966 chr2:61757674 XPO1 -0.44 -7.41 -0.37 1.02e-12 Tuberculosis; LIHC cis rs2839186 0.500 rs13049893 chr21:47707054 C/T cg12379764 chr21:47803548 PCNT -0.66 -9.49 -0.46 4.16e-19 Testicular germ cell tumor; LIHC cis rs782590 0.902 rs7582278 chr2:55742924 C/G cg18811423 chr2:55921094 PNPT1 0.97 14.95 0.63 3.11e-39 Metabolic syndrome; LIHC cis rs74233809 0.892 rs11191447 chr10:104652323 C/T cg03493300 chr10:104813866 CNNM2 0.45 5.9 0.3 8.78e-9 Birth weight; LIHC cis rs9503598 0.783 rs9503599 chr6:3451048 T/C cg00476032 chr6:3446245 SLC22A23 0.43 8.57 0.42 3.71e-16 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs244293 0.965 rs171513 chr17:53190426 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.58 -0.38 3.26e-13 Menarche (age at onset); LIHC trans rs1814175 0.645 rs1721995 chr11:49915488 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -19.79 -0.73 1.21e-58 Height; LIHC cis rs7412746 0.597 rs868751 chr1:150669414 T/G cg15448220 chr1:150897856 SETDB1 0.44 6.83 0.35 3.85e-11 Melanoma; LIHC cis rs4969178 0.965 rs3744217 chr17:76400258 G/A cg20026190 chr17:76395443 PGS1 0.45 7.12 0.36 6.52e-12 HDL cholesterol levels; LIHC cis rs9457247 1.000 rs398278 chr6:167388169 A/G cg12798992 chr6:167411361 FGFR1OP 0.52 8.07 0.4 1.24e-14 Crohn's disease; LIHC cis rs8078723 0.668 rs3859192 chr17:38128648 C/T cg17467752 chr17:38218738 THRA 0.6 10.38 0.49 3.91e-22 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs769267 0.899 rs3934667 chr19:19431423 T/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.62 -10.08 -0.48 4.34e-21 Tonsillectomy; LIHC trans rs9914544 0.966 rs1737943 chr17:18841590 A/G cg04702396 chr17:15466718 FAM18B2 -0.44 -6.85 -0.35 3.46e-11 Educational attainment (years of education); LIHC trans rs983392 0.709 rs11603507 chr11:59982470 T/A cg17275991 chr19:58003312 ZNF419 0.44 6.26 0.32 1.12e-9 Alzheimer's disease (late onset); LIHC cis rs798554 0.679 rs1636253 chr7:2885123 A/G cg04166393 chr7:2884313 GNA12 0.52 8.34 0.41 1.9e-15 Height; LIHC cis rs4423214 1.000 rs7935125 chr11:71184190 C/A cg24826892 chr11:71159390 DHCR7 0.5 6.38 0.33 5.79e-10 Vitamin D levels; LIHC cis rs1062177 1.000 rs62394155 chr5:151248069 G/A cg00977110 chr5:151150581 G3BP1 0.51 6.34 0.32 7.45e-10 Preschool internalizing problems; LIHC cis rs2274273 0.588 rs17128145 chr14:55536406 G/T cg01864836 chr14:55583639 NA 0.4 6.31 0.32 8.62e-10 Protein biomarker; LIHC cis rs2228479 0.850 rs62054599 chr16:89808850 C/G cg04013166 chr16:89971882 TCF25 0.49 6.08 0.31 3.24e-9 Skin colour saturation; LIHC cis rs2303759 0.874 rs10411630 chr19:49891314 C/A cg22307029 chr19:49891270 CCDC155 0.58 9.28 0.45 2.05e-18 Multiple sclerosis; LIHC cis rs3008870 0.755 rs2065002 chr1:67487119 A/C cg02640540 chr1:67518911 SLC35D1 -0.39 -5.86 -0.3 1.1e-8 Lymphocyte percentage of white cells; LIHC cis rs919433 0.619 rs699318 chr2:198281743 T/C cg03934865 chr2:198174659 NA 0.53 8.07 0.4 1.18e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8067354 0.540 rs12600680 chr17:58037374 T/C cg02344993 chr17:57696989 CLTC 0.65 10.28 0.49 8.95e-22 Hemoglobin concentration; LIHC cis rs2933343 0.601 rs1680758 chr3:128594897 T/C cg24203234 chr3:128598194 ACAD9 0.44 6.18 0.32 1.78e-9 IgG glycosylation; LIHC cis rs8062405 0.755 rs4788080 chr16:28558081 C/T cg00204512 chr16:28754710 NA 0.41 7.16 0.36 4.9e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg10360323 chr17:41437877 NA 0.4 6.08 0.31 3.29e-9 Menopause (age at onset); LIHC cis rs4919087 0.715 rs793524 chr10:99024572 A/G cg25902810 chr10:99078978 FRAT1 -0.55 -6.29 -0.32 9.84e-10 Monocyte count; LIHC cis rs6582630 0.555 rs2387598 chr12:38510472 G/A cg13010199 chr12:38710504 ALG10B -0.45 -6.37 -0.33 6.17e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs7666738 0.830 rs1813251 chr4:98921170 A/G cg05340658 chr4:99064831 C4orf37 0.65 12.12 0.55 2.24e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs6582630 0.519 rs11495373 chr12:38275470 T/C cg13010199 chr12:38710504 ALG10B 0.48 5.72 0.3 2.39e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs921968 0.541 rs585185 chr2:219457741 G/A cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.63e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs10411161 1.000 rs2867318 chr19:52363472 T/C cg22319618 chr22:45562946 NUP50 -0.51 -6.83 -0.35 4.01e-11 Breast cancer; LIHC cis rs769267 0.895 rs2905435 chr19:19495954 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.53 -8.14 -0.4 7.32e-15 Tonsillectomy; LIHC cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 11.44 0.53 7.19e-26 Platelet count; LIHC cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg24209194 chr3:40518798 ZNF619 -0.45 -6.61 -0.34 1.44e-10 Renal cell carcinoma; LIHC cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg02290350 chr8:58132656 NA 0.5 8.99 0.44 1.74e-17 Developmental language disorder (linguistic errors); LIHC trans rs724818 1.000 rs729243 chr4:121585651 C/T cg16091981 chr1:17634543 PADI4 -0.5 -6.12 -0.31 2.6e-9 Monobrow thickness; LIHC cis rs2932538 0.922 rs9429694 chr1:113158289 G/A cg22162597 chr1:113214053 CAPZA1 0.73 11.1 0.51 1.15e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs16858210 0.607 rs59321941 chr3:183571024 A/G cg25686905 chr3:183603175 PARL -0.49 -8.6 -0.42 2.88e-16 Menopause (age at onset); LIHC cis rs10489202 0.608 rs7533646 chr1:168077593 A/C cg24449463 chr1:168025552 DCAF6 -0.44 -6.19 -0.32 1.68e-9 Schizophrenia; LIHC cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.6 5.81 0.3 1.42e-8 Platelet count; LIHC cis rs7100689 0.577 rs9285726 chr10:82035150 A/T cg01528321 chr10:82214614 TSPAN14 0.9 12.0 0.54 6.13e-28 Post bronchodilator FEV1; LIHC cis rs2073499 1.000 rs10510755 chr3:50281168 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 0.62 6.47 0.33 3.37e-10 Schizophrenia; LIHC cis rs16854884 0.710 rs6782558 chr3:143817462 G/C cg06585982 chr3:143692056 C3orf58 0.41 5.76 0.3 1.87e-8 Economic and political preferences (feminism/equality); LIHC cis rs9513627 0.749 rs73556143 chr13:100116907 G/A cg25919922 chr13:100150906 NA -0.75 -6.38 -0.33 5.91e-10 Obesity-related traits; LIHC cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs56235845 0.694 rs4976643 chr5:176760227 A/C cg16006841 chr5:176797999 RGS14 0.57 7.53 0.38 4.56e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg25811766 chr13:21894605 NA 0.77 13.3 0.58 7.81e-33 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg19318889 chr4:1322082 MAEA 0.59 9.12 0.44 6.46e-18 Longevity; LIHC trans rs1005277 0.579 rs2504143 chr10:38383706 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8114671 0.562 rs2889861 chr20:33405664 C/T cg07148914 chr20:33460835 GGT7 0.57 8.65 0.42 2.1e-16 Height; LIHC cis rs6088813 1.000 rs6088820 chr20:33987298 T/C cg14752227 chr20:34000481 UQCC -0.4 -5.75 -0.3 1.99e-8 Height; LIHC cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg03264133 chr6:25882463 NA -0.65 -9.31 -0.45 1.57e-18 Blood metabolite levels; LIHC cis rs748404 0.631 rs8042688 chr15:43638525 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.99 0.48 9e-21 Lung cancer; LIHC cis rs7772486 0.754 rs4896838 chr6:146015451 T/C cg23711669 chr6:146136114 FBXO30 -0.71 -11.66 -0.53 1.13e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs769267 0.930 rs4808959 chr19:19572108 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.09 0.4 1.03e-14 Tonsillectomy; LIHC cis rs9457247 0.561 rs916331 chr6:167470559 T/G cg07741184 chr6:167504864 NA 0.35 8.11 0.4 9.26e-15 Crohn's disease; LIHC trans rs9302065 0.565 rs2992908 chr13:95960600 G/A cg19955956 chr7:72299837 SBDSP;TYW1B 0.36 6.57 0.33 1.83e-10 Blood metabolite levels; LIHC cis rs1144333 0.655 rs4949681 chr1:76409828 C/T cg22875332 chr1:76189707 ACADM 0.41 6.14 0.32 2.31e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs6570726 0.738 rs6925594 chr6:145898454 T/C cg05347473 chr6:146136440 FBXO30 0.38 5.89 0.3 9.44e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10788264 0.544 rs9630110 chr10:124017308 C/T cg04162153 chr10:124029871 BTBD16 -0.43 -6.03 -0.31 4.28e-9 Total body bone mineral density; LIHC cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg05368731 chr17:41323189 NBR1 0.73 12.63 0.56 2.82e-30 Menopause (age at onset); LIHC cis rs7258465 1.000 rs76194 chr19:18630580 T/G cg01065977 chr19:18549689 ISYNA1 -0.38 -5.95 -0.31 6.78e-9 Breast cancer; LIHC cis rs35110281 0.748 rs2838324 chr21:44999820 T/C cg01579765 chr21:45077557 HSF2BP -0.37 -6.87 -0.35 3e-11 Mean corpuscular volume; LIHC cis rs6543140 0.601 rs78178597 chr2:103023596 G/T cg09003973 chr2:102972529 NA 0.82 8.4 0.41 1.17e-15 Blood protein levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14734630 chr12:29533564 ERGIC2 -0.53 -6.07 -0.31 3.41e-9 Systolic blood pressure; LIHC cis rs959260 1.000 rs7226070 chr17:73372811 T/C cg20590849 chr17:73267439 MIF4GD -0.53 -5.75 -0.3 1.96e-8 Systemic lupus erythematosus; LIHC cis rs7635838 0.819 rs904474 chr3:11524648 C/G cg00170343 chr3:11313890 ATG7 0.41 6.28 0.32 1.01e-9 HDL cholesterol; LIHC cis rs1144333 0.737 rs1144331 chr1:76272357 G/A cg03433033 chr1:76189801 ACADM -0.56 -8.61 -0.42 2.7e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs939574 0.790 rs2276635 chr2:220087441 T/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.89 6.37 0.33 5.99e-10 Platelet distribution width; LIHC trans rs75804782 0.521 rs72994970 chr2:239426992 G/A cg01134436 chr17:81009848 B3GNTL1 0.75 6.37 0.33 6.12e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs769267 0.930 rs747050 chr19:19584987 C/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.87 0.3 1.01e-8 Tonsillectomy; LIHC cis rs8180040 0.654 rs62246451 chr3:47211632 C/T cg27129171 chr3:47204927 SETD2 -0.58 -9.56 -0.46 2.43e-19 Colorectal cancer; LIHC cis rs62380364 0.626 rs618741 chr5:88064012 C/T cg22951263 chr5:87985283 NA -0.41 -7.17 -0.36 4.71e-12 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg12310025 chr6:25882481 NA -0.74 -9.39 -0.45 8.5e-19 Intelligence (multi-trait analysis); LIHC cis rs7238033 0.624 rs8099449 chr18:43311696 T/C cg20610511 chr18:43302872 SLC14A1 0.38 6.34 0.32 7.44e-10 Bladder cancer; LIHC cis rs7582180 0.614 rs3748930 chr2:101010082 G/C cg14675211 chr2:100938903 LONRF2 0.56 8.26 0.41 3.22e-15 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg15691649 chr6:25882328 NA 0.59 7.93 0.39 3.16e-14 Intelligence (multi-trait analysis); LIHC cis rs12291225 0.585 rs34171876 chr11:14353957 G/C cg05501817 chr11:14380813 RRAS2 -0.45 -6.32 -0.32 8.29e-10 Sense of smell; LIHC trans rs2727020 0.612 rs9787891 chr11:49413494 G/A cg15704280 chr7:45808275 SEPT13 -0.79 -12.55 -0.56 5.8e-30 Coronary artery disease; LIHC cis rs7772486 0.875 rs2814874 chr6:146305895 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.39 -0.33 5.54e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 1.000 rs56358680 chr16:28843118 A/G cg07451762 chr16:28383216 NA 0.32 6.09 0.31 3.1e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs910316 0.967 rs4899550 chr14:75647666 C/T cg08847533 chr14:75593920 NEK9 -0.85 -17.47 -0.69 2.6e-49 Height; LIHC cis rs8058578 0.832 rs3812999 chr16:30773605 G/T cg02466173 chr16:30829666 NA -0.42 -6.66 -0.34 1.08e-10 Multiple myeloma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00226754 chr12:124068984 TMED2 -0.41 -6.71 -0.34 8.33e-11 Pancreatic cancer; LIHC cis rs7618501 0.633 rs11925192 chr3:50038664 G/A cg24110177 chr3:50126178 RBM5 -0.46 -7.56 -0.38 3.67e-13 Intelligence (multi-trait analysis); LIHC cis rs4474465 0.573 rs7101478 chr11:78272517 C/A cg27205649 chr11:78285834 NARS2 0.43 6.78 0.34 5.36e-11 Alzheimer's disease (survival time); LIHC cis rs8017423 0.935 rs3783838 chr14:90733012 A/G cg14092571 chr14:90743983 NA 0.44 7.06 0.36 9.47e-12 Mortality in heart failure; LIHC cis rs4595586 0.545 rs67985200 chr12:39386891 C/T cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs6565180 0.888 rs13333093 chr16:30407269 C/A cg17640201 chr16:30407289 ZNF48 0.8 13.74 0.6 1.58e-34 Tonsillectomy; LIHC cis rs4788570 0.727 rs7204118 chr16:71833658 G/C cg06353428 chr16:71660113 MARVELD3 1.3 13.62 0.59 4.58e-34 Intelligence (multi-trait analysis); LIHC cis rs17384381 0.834 rs11161614 chr1:85898160 A/C cg16011679 chr1:85725395 C1orf52 0.58 6.95 0.35 1.85e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.778 rs10745357 chr1:110001876 G/C cg11161837 chr1:110010384 SYPL2 0.45 6.15 0.32 2.11e-9 Intelligence (multi-trait analysis); LIHC cis rs595982 0.527 rs56021835 chr19:49369989 G/A cg15549821 chr19:49342101 PLEKHA4 -0.67 -6.16 -0.32 2.04e-9 Red cell distribution width; LIHC cis rs7917772 0.636 rs4919676 chr10:104524352 C/T cg22532475 chr10:104410764 TRIM8 0.36 6.34 0.32 7.18e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -5.91 -0.3 8.23e-9 Renal cell carcinoma; LIHC cis rs8060686 0.621 rs35432211 chr16:68095449 T/C cg09835421 chr16:68378352 PRMT7 -0.49 -5.77 -0.3 1.8e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs546131 0.642 rs836950 chr11:34852020 C/G cg11058730 chr11:34937778 PDHX;APIP -0.64 -9.41 -0.45 7.21e-19 Lung disease severity in cystic fibrosis; LIHC cis rs60871478 1.000 rs4720930 chr7:808073 G/A cg13844804 chr7:814759 HEATR2 0.44 5.89 0.3 9.39e-9 Cerebrospinal P-tau181p levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17315132 chr17:27169875 C17orf63 -0.52 -6.08 -0.31 3.14e-9 Systolic blood pressure; LIHC cis rs7106204 0.609 rs12790279 chr11:24286221 C/G ch.11.24196551F chr11:24239977 NA 0.61 6.65 0.34 1.17e-10 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4808199 0.895 rs8105984 chr19:19374068 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.34 0.37 1.56e-12 Nonalcoholic fatty liver disease; LIHC cis rs7520050 0.966 rs4660898 chr1:46402171 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.76 0.3 1.86e-8 Red blood cell count;Reticulocyte count; LIHC cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg10360323 chr17:41437877 NA 0.4 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs6570726 0.791 rs6902410 chr6:145905261 G/A cg23711669 chr6:146136114 FBXO30 0.7 12.05 0.55 4.21e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs2463822 1.000 rs2513074 chr11:62100880 A/C cg06239285 chr11:62104954 ASRGL1 0.93 7.14 0.36 5.5e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs6582630 0.599 rs7967598 chr12:38540760 C/T cg26384229 chr12:38710491 ALG10B -0.5 -7.04 -0.36 1.04e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs7412746 0.634 rs2124952 chr1:150923774 T/A cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs12928939 0.815 rs10500560 chr16:71681153 G/A cg03805757 chr16:71968109 PKD1L3 -0.68 -7.41 -0.37 1.01e-12 Post bronchodilator FEV1; LIHC cis rs1030877 0.960 rs3792050 chr2:105902255 T/C cg02079111 chr2:105885981 TGFBRAP1 -0.69 -12.34 -0.55 3.49e-29 Obesity-related traits; LIHC cis rs11758351 0.660 rs56398712 chr6:26213868 A/G cg03854865 chr6:26224070 HIST1H3E 0.59 6.43 0.33 4.36e-10 Gout;Renal underexcretion gout; LIHC cis rs6582630 0.519 rs12368889 chr12:38315160 G/A cg26384229 chr12:38710491 ALG10B 0.87 10.8 0.5 1.34e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg05896524 chr21:47604654 C21orf56 0.5 7.74 0.39 1.14e-13 Testicular germ cell tumor; LIHC cis rs7208859 0.673 rs11655623 chr17:29162173 T/C cg13385521 chr17:29058706 SUZ12P 0.79 7.88 0.39 4.55e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg06873352 chr17:61820015 STRADA -0.52 -7.75 -0.39 1.05e-13 Height; LIHC cis rs6860806 0.531 rs272887 chr5:131665713 A/G cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.82e-31 Breast cancer; LIHC cis rs11677370 0.561 rs12986995 chr2:3826965 G/A cg17052675 chr2:3827356 NA -0.58 -7.79 -0.39 7.88e-14 Type 2 diabetes; LIHC cis rs6062302 0.522 rs2297427 chr20:62221364 G/A cg09650180 chr20:62225654 GMEB2 -0.37 -5.73 -0.3 2.22e-8 Glioblastoma; LIHC cis rs986417 0.748 rs4141684 chr14:61069351 C/T cg27398547 chr14:60952738 C14orf39 0.49 5.93 0.31 7.3e-9 Gut microbiota (bacterial taxa); LIHC cis rs1003719 0.743 rs2835615 chr21:38497303 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.76 -11.88 -0.54 1.78e-27 Eye color traits; LIHC cis rs1983891 0.955 rs4714480 chr6:41520891 T/C cg20194872 chr6:41519635 FOXP4 0.42 6.61 0.34 1.48e-10 Prostate cancer; LIHC cis rs9534288 0.742 rs1022953 chr13:46649126 G/T cg15192986 chr13:46630673 CPB2 -0.42 -6.12 -0.31 2.49e-9 Blood protein levels; LIHC cis rs2425143 1.000 rs73905926 chr20:34251982 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.84 -0.3 1.2e-8 Blood protein levels; LIHC cis rs1728785 0.892 rs1617749 chr16:68580890 A/G cg02972257 chr16:68554789 NA -0.56 -6.18 -0.32 1.79e-9 Ulcerative colitis; LIHC cis rs8177179 0.904 rs1130459 chr3:133465283 A/G cg24879335 chr3:133465180 TF 0.46 10.41 0.49 3.25e-22 Iron status biomarkers (transferrin levels); LIHC cis rs34172651 0.517 rs2303083 chr16:24835168 G/A cg00339695 chr16:24857497 SLC5A11 0.74 10.16 0.48 2.23e-21 Intelligence (multi-trait analysis); LIHC cis rs8062405 1.000 rs62036617 chr16:28827498 T/C cg07451762 chr16:28383216 NA 0.33 6.2 0.32 1.62e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs311392 0.554 rs369839 chr8:55097431 A/C cg11783602 chr8:55087084 NA -0.31 -6.16 -0.32 2.05e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs611744 0.529 rs13282825 chr8:109263237 T/C cg21045802 chr8:109455806 TTC35 0.59 10.51 0.49 1.41e-22 Dupuytren's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04421424 chr19:57791681 ZNF460 0.45 6.19 0.32 1.68e-9 Pancreatic cancer; LIHC cis rs9814567 0.964 rs9815894 chr3:134282796 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs75908454 1.000 rs74665543 chr6:169799665 G/A cg19338460 chr6:170058176 WDR27 -0.83 -7.52 -0.38 4.91e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs2832191 0.716 rs2297252 chr21:30377104 G/A cg24692254 chr21:30365293 RNF160 0.86 15.7 0.65 3.3e-42 Dental caries; LIHC cis rs12744310 0.830 rs12045184 chr1:41799611 G/A cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16426870 chr16:23652487 PALB2;DCTN5 -0.48 -6.45 -0.33 3.91e-10 Pancreatic cancer; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg22663859 chr13:21900854 NA 0.44 7.24 0.36 3.07e-12 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs1371867 0.846 rs1660332 chr8:101309490 A/G cg06002616 chr8:101225028 SPAG1 0.36 5.95 0.31 6.53e-9 Atrioventricular conduction; LIHC cis rs2832077 0.527 rs1048546 chr21:30244877 G/T cg24692254 chr21:30365293 RNF160 -0.42 -6.47 -0.33 3.42e-10 Cognitive test performance; LIHC cis rs35110281 0.837 rs2838341 chr21:45076443 A/G cg04455712 chr21:45112962 RRP1B 0.44 7.63 0.38 2.42e-13 Mean corpuscular volume; LIHC cis rs875971 1.000 rs1981798 chr7:65954903 G/T cg11764359 chr7:65958608 NA 0.89 16.15 0.66 5.35e-44 Aortic root size; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.04 -0.31 3.95e-9 Total body bone mineral density; LIHC cis rs7216064 1.000 rs9913471 chr17:65874495 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2075371 0.933 rs431306 chr7:133955974 A/T cg11752832 chr7:134001865 SLC35B4 0.5 7.74 0.39 1.13e-13 Mean platelet volume; LIHC cis rs8017423 0.967 rs11621364 chr14:90709115 A/G cg04374321 chr14:90722782 PSMC1 0.75 14.46 0.62 2.57e-37 Mortality in heart failure; LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg22963979 chr7:1858916 MAD1L1 -0.45 -7.27 -0.37 2.51e-12 Bipolar disorder and schizophrenia; LIHC cis rs1395 0.744 rs62130714 chr2:27532870 A/G cg22903471 chr2:27725779 GCKR -0.43 -6.29 -0.32 9.47e-10 Blood metabolite levels; LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg07677032 chr17:61819896 STRADA 0.42 5.81 0.3 1.43e-8 Prudent dietary pattern; LIHC cis rs7772486 0.790 rs2253307 chr6:146196181 T/G cg23711669 chr6:146136114 FBXO30 0.66 11.85 0.54 2.32e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs17685 0.712 rs28456330 chr7:75810542 A/G cg04610667 chr7:75704037 NA -0.35 -6.37 -0.33 6.11e-10 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1624005 1.000 rs1624005 chr14:43382362 A/G cg11960719 chr5:1510684 LPCAT1 -0.36 -6.39 -0.33 5.29e-10 Methotrexate-induced interstitial lung disease in rheumatoid arthritis; LIHC cis rs769267 0.965 rs13964 chr19:19468710 C/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.6 -9.47 -0.46 4.59e-19 Tonsillectomy; LIHC cis rs9303401 0.527 rs34835800 chr17:56764990 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.92 11.63 0.53 1.43e-26 Cognitive test performance; LIHC cis rs80282103 0.764 rs7093915 chr10:1107341 A/G cg18964960 chr10:1102726 WDR37 -0.68 -6.55 -0.33 2.14e-10 Glomerular filtration rate (creatinine); LIHC cis rs4803468 1.000 rs3816037 chr19:41918009 C/T cg14132834 chr19:41945861 ATP5SL -0.43 -6.41 -0.33 4.8e-10 Height; LIHC cis rs2625529 0.824 rs16956328 chr15:72143855 A/T cg16672083 chr15:72433130 SENP8 -0.31 -5.73 -0.3 2.16e-8 Red blood cell count; LIHC cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg25894440 chr7:65020034 NA -0.53 -6.17 -0.32 1.93e-9 Diabetic kidney disease; LIHC cis rs1707322 1.000 rs4660328 chr1:46444831 G/T cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1005277 0.522 rs9418276 chr10:37940116 G/T cg17830980 chr10:43048298 ZNF37B -0.42 -8.09 -0.4 1.03e-14 Extrinsic epigenetic age acceleration; LIHC cis rs1707322 1.000 rs4489497 chr1:46438698 C/T cg06784218 chr1:46089804 CCDC17 0.36 6.55 0.33 2.13e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3743104 0.534 rs11854391 chr15:33022582 A/T cg07179000 chr15:33023586 GREM1 -0.52 -8.19 -0.4 5.32e-15 Hypospadias; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg01546424 chr6:149721457 MAP3K7IP2;SUMO4 0.64 6.4 0.33 5.08e-10 Mean platelet volume; LIHC cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.22 0.55 9.58e-29 Alzheimer's disease; LIHC cis rs7044106 0.718 rs1960421 chr9:123394894 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.69 0.38 1.59e-13 Hip circumference adjusted for BMI; LIHC cis rs1577917 0.798 rs7772384 chr6:86639680 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.76 -0.5 1.82e-23 Response to antipsychotic treatment; LIHC cis rs2235642 0.928 rs2076435 chr16:1607574 C/T cg03034668 chr16:1723424 CRAMP1L -0.39 -6.8 -0.35 4.74e-11 Coronary artery disease; LIHC cis rs6912958 0.559 rs107690 chr6:88069352 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.6 -11.37 -0.52 1.22e-25 Monocyte percentage of white cells; LIHC cis rs4144743 1.000 rs4144745 chr17:45323349 T/C cg18085866 chr17:45331354 ITGB3 -0.59 -8.57 -0.42 3.74e-16 Body mass index; LIHC cis rs17685 0.753 rs1806885 chr7:75785612 T/G cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg12419862 chr22:24373484 LOC391322 -0.96 -16.76 -0.67 1.89e-46 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs5758511 0.508 rs28715885 chr22:42441091 T/G cg00645731 chr22:42541494 CYP2D7P1 0.58 5.88 0.3 9.67e-9 Birth weight; LIHC cis rs10106298 0.901 rs1434281 chr8:103671080 G/A cg10187029 chr8:103597600 NA 0.52 6.79 0.34 5.1e-11 Schizophrenia; LIHC cis rs507080 0.922 rs508640 chr11:118564413 A/G cg04173919 chr11:118528438 PHLDB1 0.35 6.57 0.33 1.89e-10 Serum metabolite levels; LIHC cis rs6089584 0.854 rs8117075 chr20:60613766 T/C cg23262073 chr20:60523788 NA -0.29 -5.94 -0.31 6.89e-9 Body mass index; LIHC cis rs2842992 0.789 rs6908680 chr6:160218209 G/T cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.91 0.43 3.13e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs62103177 0.525 rs62101233 chr18:77724288 C/T cg20368463 chr18:77673604 PQLC1 0.46 5.77 0.3 1.74e-8 Opioid sensitivity; LIHC cis rs17125944 0.542 rs75723366 chr14:53256882 T/C cg00686598 chr14:53173677 PSMC6 1.28 15.64 0.65 5.7700000000000006e-42 Alzheimer's disease (late onset); LIHC cis rs10876993 0.928 rs10082911 chr12:58104104 C/A cg04478727 chr12:58166393 METTL1;FAM119B -0.42 -5.87 -0.3 1.01e-8 Celiac disease or Rheumatoid arthritis; LIHC cis rs7587476 0.682 rs13009646 chr2:215691259 T/A cg04530015 chr2:215796436 ABCA12 -0.39 -6.36 -0.33 6.61e-10 Neuroblastoma; LIHC cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg09904177 chr6:26538194 HMGN4 0.56 11.04 0.51 1.99e-24 Intelligence (multi-trait analysis); LIHC cis rs4934494 1.000 rs4934494 chr10:91447419 G/A cg19698084 chr10:91461284 KIF20B -0.45 -6.09 -0.31 2.97e-9 Red blood cell count; LIHC cis rs10751667 0.961 rs10902263 chr11:992691 A/C ch.11.42038R chr11:967971 AP2A2 -0.59 -10.79 -0.5 1.5e-23 Alzheimer's disease (late onset); LIHC cis rs56104184 0.775 rs73061695 chr19:49399988 T/C cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg18501264 chr19:33555827 RHPN2 -0.44 -6.13 -0.31 2.39e-9 Hepatitis; LIHC cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg10295955 chr4:187884368 NA -0.96 -22.55 -0.77 1.2e-69 Lobe attachment (rater-scored or self-reported); LIHC cis rs6570726 0.791 rs414297 chr6:145887556 C/T cg05347473 chr6:146136440 FBXO30 0.36 5.95 0.31 6.53e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12478296 0.792 rs6755390 chr2:243012998 C/T cg06360820 chr2:242988706 NA -0.81 -11.16 -0.52 6.97e-25 Obesity-related traits; LIHC cis rs644799 0.965 rs607039 chr11:95547086 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10276381 0.901 rs73300638 chr7:28187344 A/C cg23620719 chr7:28220237 JAZF1 0.63 7.88 0.39 4.49e-14 Crohn's disease; LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.23 0.81 4.46e-80 Prudent dietary pattern; LIHC cis rs7582180 0.629 rs13031508 chr2:100952757 A/G cg14675211 chr2:100938903 LONRF2 0.53 8.33 0.41 2.02e-15 Intelligence (multi-trait analysis); LIHC cis rs12472274 0.941 rs6748440 chr2:239100375 C/T cg17459225 chr2:239074497 NA 0.77 12.76 0.57 9.08e-31 Phospholipid levels (plasma); LIHC cis rs12893668 0.673 rs2296482 chr14:104029819 T/G cg19000871 chr14:103996768 TRMT61A -0.43 -7.05 -0.36 9.88e-12 Reticulocyte count; LIHC cis rs1577917 0.917 rs35738006 chr6:86646309 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.63 -0.5 5.24e-23 Response to antipsychotic treatment; LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs11671005 0.735 rs12977592 chr19:58961056 C/G cg25952890 chr19:58913133 NA 0.55 6.29 0.32 9.86e-10 Mean platelet volume; LIHC cis rs2404602 0.684 rs11854850 chr15:76844571 C/T cg23625390 chr15:77176239 SCAPER -0.56 -9.34 -0.45 1.27e-18 Blood metabolite levels; LIHC cis rs6750047 0.605 rs1374191 chr2:38265420 T/G cg07380506 chr2:38303506 CYP1B1 -0.58 -7.41 -0.37 1.02e-12 Cutaneous malignant melanoma;Melanoma; LIHC cis rs7534824 0.625 rs55693426 chr1:101466859 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 7.48 0.37 6.36e-13 Refractive astigmatism; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs7107174 1.000 rs7939352 chr11:78003151 G/A cg02023728 chr11:77925099 USP35 0.45 8.8 0.43 7.12e-17 Testicular germ cell tumor; LIHC cis rs11122272 0.667 rs2244992 chr1:231537220 T/C cg06096015 chr1:231504339 EGLN1 0.49 9.18 0.44 4.06e-18 Hemoglobin concentration; LIHC cis rs7847628 0.566 rs10739575 chr9:123606101 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.53 -7.04 -0.36 1.06e-11 Birth weight; LIHC cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.64 0.34 1.25e-10 Bipolar disorder; LIHC cis rs1559088 0.847 rs6510348 chr19:33601946 G/A cg27124370 chr19:33622961 WDR88 0.52 8.19 0.41 5.16e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs72781680 0.800 rs56398785 chr2:24091515 T/A cg08917208 chr2:24149416 ATAD2B 0.96 8.55 0.42 4.3e-16 Lymphocyte counts; LIHC cis rs912057 0.833 rs1294418 chr6:6742185 A/G cg06612196 chr6:6737390 NA 0.52 9.78 0.47 4.38e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs796364 0.951 rs281769 chr2:200809709 T/C cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.61e-9 Schizophrenia; LIHC cis rs769267 0.895 rs2905435 chr19:19495954 G/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.42 -5.95 -0.31 6.76e-9 Tonsillectomy; LIHC cis rs854765 0.647 rs2974998 chr17:17995619 A/G cg04398451 chr17:18023971 MYO15A -0.66 -10.9 -0.51 6.27e-24 Total body bone mineral density; LIHC cis rs748404 0.631 rs6493086 chr15:43655394 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.99 0.48 9e-21 Lung cancer; LIHC cis rs727505 1.000 rs10233596 chr7:124556659 A/G cg23710748 chr7:124431027 NA -0.33 -5.82 -0.3 1.39e-8 Lewy body disease; LIHC cis rs6840360 0.554 rs62329088 chr4:152471289 C/T cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs7487075 0.619 rs6582658 chr12:46856095 G/A cg23829395 chr12:46796953 NA 0.34 6.06 0.31 3.54e-9 Itch intensity from mosquito bite; LIHC cis rs7914558 0.902 rs3736922 chr10:104850632 A/G cg15744005 chr10:104629667 AS3MT 0.39 8.68 0.42 1.64e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs10506458 1.000 rs11174759 chr12:63444363 A/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.42 -0.49 2.92e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs10540 0.915 rs12419209 chr11:494510 T/C cg03576123 chr11:487126 PTDSS2 -1.16 -8.66 -0.42 1.9e-16 Body mass index; LIHC cis rs11583043 1.000 rs34915449 chr1:101476786 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.71 0.43 1.35e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7223966 1.000 rs9901112 chr17:61730617 C/G cg05941027 chr17:61774174 LIMD2 0.34 6.91 0.35 2.32e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs10779751 0.734 rs2791647 chr1:11132801 G/A cg08854313 chr1:11322531 MTOR 0.66 10.04 0.48 6.06e-21 Body mass index; LIHC cis rs611744 0.647 rs7016198 chr8:109262752 G/A cg18478394 chr8:109455254 TTC35 0.42 7.24 0.36 2.98e-12 Dupuytren's disease; LIHC cis rs6582630 0.519 rs8189461 chr12:38374870 G/T cg26384229 chr12:38710491 ALG10B 0.59 8.22 0.41 4.31e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs1865760 0.929 rs1436307 chr6:25939723 C/T cg03264133 chr6:25882463 NA -0.42 -6.26 -0.32 1.17e-9 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08204369 chr17:73150733 HN1 0.43 7.14 0.36 5.65e-12 Cognitive function; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg06601766 chr17:61851465 DDX42;CCDC47 -0.59 -9.04 -0.44 1.18e-17 Height; LIHC cis rs8038465 0.592 rs1542580 chr15:73935834 C/G cg15420318 chr15:73925796 NPTN 0.49 7.55 0.38 4.06e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4319547 0.695 rs10773103 chr12:122856532 A/G cg23029597 chr12:123009494 RSRC2 0.52 7.35 0.37 1.46e-12 Body mass index; LIHC cis rs7904368 0.951 rs7905776 chr10:16853609 C/T cg23933602 chr10:16859644 RSU1 0.59 5.99 0.31 5.46e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs1046896 0.731 rs8067667 chr17:80785875 A/G cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.42 0.37 9.46e-13 Glycated hemoglobin levels; LIHC trans rs561341 1.000 rs506766 chr17:30289659 T/C cg20587970 chr11:113659929 NA -1.34 -10.6 -0.5 6.85e-23 Hip circumference adjusted for BMI; LIHC cis rs6570726 0.967 rs418662 chr6:145848832 A/C cg23711669 chr6:146136114 FBXO30 0.52 9.27 0.45 2.15e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs7635838 0.587 rs347591 chr3:11290122 G/T cg00170343 chr3:11313890 ATG7 0.52 8.25 0.41 3.56e-15 HDL cholesterol; LIHC cis rs9921222 1.000 rs9921222 chr16:375782 A/G cg26913058 chr16:419975 MRPL28 0.43 5.92 0.3 7.97e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs7412746 0.597 rs868751 chr1:150669414 T/G cg18016565 chr1:150552671 MCL1 0.59 11.56 0.53 2.67e-26 Melanoma; LIHC cis rs61677309 1.000 rs56785719 chr11:118176623 C/G cg06090739 chr11:118230722 UBE4A 0.34 6.14 0.32 2.27e-9 Lung cancer in ever smokers; LIHC cis rs9902453 0.765 rs8079209 chr17:28186773 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 14.42 0.61 3.81e-37 Coffee consumption (cups per day); LIHC cis rs11031096 0.502 rs1442726 chr11:4094748 G/C cg18678763 chr11:4115507 RRM1 -0.59 -8.78 -0.43 7.9e-17 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2153535 0.580 rs1932276 chr6:8442593 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs11792861 0.890 rs3087979 chr9:111781779 T/C cg13535736 chr9:111863775 C9orf5 -0.41 -6.22 -0.32 1.44e-9 Menarche (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19684392 chr10:44144386 ZNF32 0.48 6.34 0.32 7.4e-10 Lung function (FEV1/FVC); LIHC cis rs34779708 0.931 rs35388511 chr10:35296616 A/G cg03585969 chr10:35415529 CREM 0.78 11.75 0.54 5.36e-27 Inflammatory bowel disease;Crohn's disease; LIHC trans rs9929218 0.954 rs9929479 chr16:68821271 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.44 -0.42 9.07e-16 Colorectal cancer; LIHC cis rs2073499 1.000 rs3806708 chr3:50306249 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.6 6.67 0.34 1.03e-10 Schizophrenia; LIHC cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs5769765 1.000 rs761879 chr22:50241210 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.74 9.25 0.45 2.43e-18 Schizophrenia; LIHC cis rs360798 0.512 rs2710637 chr2:63173450 G/A cg17519650 chr2:63277830 OTX1 0.46 7.13 0.36 5.99e-12 Coronary artery disease; LIHC cis rs7131987 0.650 rs12366527 chr12:29474256 C/G cg14222432 chr12:29376421 FAR2 0.36 6.93 0.35 2.16e-11 QT interval; LIHC trans rs7618501 0.966 rs9882639 chr3:49799475 A/C cg21582582 chr3:182698605 DCUN1D1 0.52 6.87 0.35 3.02e-11 Intelligence (multi-trait analysis); LIHC cis rs3784262 1.000 rs1372368 chr15:58297363 C/T cg12031962 chr15:58353849 ALDH1A2 -0.35 -7.02 -0.35 1.22e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg23758822 chr17:41437982 NA 0.94 17.91 0.7 4.61e-51 Menopause (age at onset); LIHC cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 11.7 0.53 8.25e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg05665937 chr4:1216051 CTBP1 -0.45 -6.07 -0.31 3.35e-9 Obesity-related traits; LIHC cis rs933688 0.938 rs7708782 chr5:90718517 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.7 0.73 2.92e-58 Smoking behavior; LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg14671364 chr1:107599128 PRMT6 0.49 7.38 0.37 1.25e-12 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6500602 0.727 rs11076836 chr16:4569331 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 5.93 0.31 7.43e-9 Schizophrenia; LIHC cis rs12220238 1.000 rs7083534 chr10:75955672 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.37 0.33 6.13e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1865760 0.964 rs9295677 chr6:25933712 T/C cg12310025 chr6:25882481 NA -0.41 -6.11 -0.31 2.68e-9 Height; LIHC cis rs9868809 0.772 rs9877501 chr3:48718390 C/G cg07636037 chr3:49044803 WDR6 -0.58 -6.51 -0.33 2.63e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs11971779 0.590 rs6467839 chr7:139062790 T/C cg07862535 chr7:139043722 LUC7L2 0.58 10.03 0.48 6.11e-21 Diisocyanate-induced asthma; LIHC cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg10802521 chr3:52805072 NEK4 -0.43 -7.01 -0.35 1.24e-11 Bipolar disorder; LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.68 -0.34 9.67e-11 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05038121 chr15:80444758 FAH 0.51 6.85 0.35 3.46e-11 Pancreatic cancer; LIHC cis rs7927771 0.929 rs12787646 chr11:47669665 T/C cg20307385 chr11:47447363 PSMC3 -0.46 -6.13 -0.31 2.48e-9 Subjective well-being; LIHC cis rs9733 0.569 rs11588404 chr1:150688529 C/A cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs644799 1.000 rs632388 chr11:95563775 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.68e-17 Prudent dietary pattern; LIHC cis rs2120019 0.938 rs8036573 chr15:75308690 C/T cg16226627 chr15:75307476 SCAMP5 0.36 6.95 0.35 1.81e-11 Blood trace element (Zn levels); LIHC cis rs11758351 0.866 rs77889957 chr6:26207435 A/G cg23601095 chr6:26197514 HIST1H3D 0.54 5.79 0.3 1.58e-8 Gout;Renal underexcretion gout; LIHC cis rs116095464 0.558 rs13356367 chr5:242395 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.7 -0.5 3.15e-23 Breast cancer; LIHC cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg12463550 chr7:65579703 CRCP 0.67 7.02 0.36 1.17e-11 Diabetic kidney disease; LIHC cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg11502198 chr6:26597334 ABT1 0.61 9.71 0.47 7.37e-20 Intelligence (multi-trait analysis); LIHC cis rs17286411 0.671 rs9936903 chr16:71727571 A/T cg06353428 chr16:71660113 MARVELD3 0.45 6.66 0.34 1.06e-10 Blood protein levels; LIHC cis rs787274 0.543 rs10116897 chr9:115633479 C/T cg13803584 chr9:115635662 SNX30 -0.63 -9.01 -0.44 1.5e-17 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg24531977 chr5:56204891 C5orf35 -0.68 -9.88 -0.47 2e-20 Initial pursuit acceleration; LIHC cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg23205692 chr1:25664452 TMEM50A 0.41 6.61 0.34 1.51e-10 Erythrocyte sedimentation rate; LIHC cis rs10193935 1.000 rs13424523 chr2:42413562 T/G cg27598129 chr2:42591480 NA -0.73 -11.01 -0.51 2.42e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs7312933 0.576 rs11181364 chr12:42567800 C/T cg01256987 chr12:42539512 GXYLT1 -0.42 -7.07 -0.36 9.02e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs344364 0.602 rs2983907 chr16:1913336 C/T cg00564555 chr16:1970112 NA 0.26 6.14 0.32 2.24e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs3812831 0.662 rs418027 chr13:114929344 A/C cg06611532 chr13:114900021 NA 0.38 7.04 0.36 1.06e-11 Schizophrenia; LIHC cis rs4819052 0.851 rs2838844 chr21:46670733 A/C cg22633049 chr21:46681294 NA -0.36 -6.12 -0.31 2.5e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7666738 0.830 rs13141752 chr4:98893128 G/A cg05340658 chr4:99064831 C4orf37 0.66 11.9 0.54 1.49e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs12971120 0.838 rs2241510 chr18:72180739 G/A cg26446133 chr18:72167187 CNDP2 -0.79 -14.05 -0.6 1.07e-35 Refractive error; LIHC cis rs739401 0.611 rs12284275 chr11:3024384 T/C cg08508325 chr11:3079039 CARS -0.32 -6.8 -0.35 4.58e-11 Longevity; LIHC cis rs4407350 1.000 rs4386428 chr22:44922359 T/G cg26276947 chr22:44892394 LDOC1L 0.35 6.35 0.32 6.81e-10 Intelligence (multi-trait analysis); LIHC trans rs783540 0.967 rs4779044 chr15:83339353 A/C cg18393722 chr15:85113863 UBE2QP1 0.38 6.6 0.34 1.56e-10 Schizophrenia; LIHC cis rs9814567 1.000 rs62271515 chr3:134300507 T/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.86 -0.3 1.07e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs763121 0.853 rs5750677 chr22:39147715 C/T cg14440974 chr22:39074834 NA -0.39 -6.34 -0.32 7.42e-10 Menopause (age at onset); LIHC cis rs4638749 0.734 rs6542756 chr2:108865629 C/G cg25838818 chr2:108905173 SULT1C2 -0.39 -6.93 -0.35 2.11e-11 Blood pressure; LIHC cis rs12134245 0.776 rs61548854 chr1:92001536 C/T cg07090678 chr1:91966139 CDC7 0.51 6.96 0.35 1.72e-11 Breast cancer; LIHC cis rs16912285 0.748 rs58504811 chr11:24252020 T/G ch.11.24196551F chr11:24239977 NA 0.74 9.5 0.46 3.66e-19 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs12971120 0.891 rs2303463 chr18:72168608 G/A cg25817165 chr18:72167213 CNDP2 -0.7 -12.3 -0.55 4.76e-29 Refractive error; LIHC cis rs9393692 0.905 rs34916901 chr6:26286149 G/T cg05868516 chr6:26286170 HIST1H4H 0.43 6.59 0.34 1.69e-10 Educational attainment; LIHC cis rs8180040 0.800 rs11921117 chr3:47294000 T/C cg27129171 chr3:47204927 SETD2 -0.56 -9.1 -0.44 7.45e-18 Colorectal cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05610740 chr12:96794311 CDK17 0.48 6.75 0.34 6.51e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11718455 0.921 rs11130020 chr3:44009459 C/T cg08738300 chr3:44038990 NA 0.49 8.49 0.42 6.33e-16 Coronary artery disease; LIHC cis rs2380220 0.541 rs72928277 chr6:96079745 G/T cg15832292 chr6:96025679 MANEA -0.73 -9.17 -0.44 4.46e-18 Behavioural disinhibition (generation interaction); LIHC cis rs7923837 0.713 rs10882099 chr10:94460650 T/C cg25093409 chr10:94429542 NA 0.33 5.82 0.3 1.34e-8 Body mass index;Multiple sclerosis; LIHC cis rs6545883 1.000 rs6742276 chr2:61768745 G/A cg14146966 chr2:61757674 XPO1 0.48 8.51 0.42 5.64e-16 Tuberculosis; LIHC trans rs12310956 0.532 rs10506119 chr12:33963684 A/G cg26384229 chr12:38710491 ALG10B 0.53 7.28 0.37 2.27e-12 Morning vs. evening chronotype; LIHC cis rs6089584 0.821 rs2273990 chr20:60579149 G/T cg23262073 chr20:60523788 NA -0.28 -5.73 -0.3 2.24e-8 Body mass index; LIHC cis rs7771547 0.573 rs547026 chr6:36398616 G/A cg07856975 chr6:36356162 ETV7 0.36 5.86 0.3 1.08e-8 Platelet distribution width; LIHC cis rs7100689 0.646 rs4357632 chr10:82131783 C/T cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs7572733 0.534 rs2060488 chr2:198751637 T/G cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.5e-11 Dermatomyositis; LIHC cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 2.97e-30 Menopause (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13749424 chr17:80416444 NARF 0.54 6.79 0.34 5.09e-11 Hepatitis; LIHC cis rs7666738 0.546 rs34621463 chr4:98793357 G/C cg05340658 chr4:99064831 C4orf37 0.51 6.7 0.34 8.84e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs921968 0.565 rs692049 chr2:219622778 G/A cg02985541 chr2:219472218 PLCD4 -0.38 -6.58 -0.34 1.8e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs3736485 0.934 rs114641722 chr15:51863572 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8027181 0.839 rs4777532 chr15:73041767 A/G cg25632853 chr15:73088954 NA 0.36 6.05 0.31 3.77e-9 Triglyceride levels; LIHC cis rs1799949 0.965 rs8071278 chr17:41193910 A/T cg05368731 chr17:41323189 NBR1 0.7 11.58 0.53 2.14e-26 Menopause (age at onset); LIHC cis rs6545883 0.894 rs6739427 chr2:61452879 T/C cg15711740 chr2:61764176 XPO1 0.43 5.8 0.3 1.52e-8 Tuberculosis; LIHC cis rs7546668 1.000 rs9298 chr1:15897020 C/T cg11706911 chr1:15910989 AGMAT 0.44 6.72 0.34 7.78e-11 Glomerular filtration rate (creatinine); LIHC cis rs758324 0.947 rs4493667 chr5:131247218 G/T cg06307176 chr5:131281290 NA -0.4 -5.79 -0.3 1.57e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg08219700 chr8:58056026 NA 0.53 7.07 0.36 8.71e-12 Developmental language disorder (linguistic errors); LIHC cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg13395646 chr4:1353034 KIAA1530 0.39 5.85 0.3 1.15e-8 Longevity; LIHC trans rs2363709 0.892 rs2087553 chr3:67428164 G/A cg25028035 chr6:42016671 CCND3 -0.85 -6.09 -0.31 3.07e-9 IgE levels; LIHC cis rs12762955 0.561 rs4880744 chr10:1012026 A/G cg26597838 chr10:835615 NA -0.47 -5.75 -0.3 1.93e-8 Response to angiotensin II receptor blocker therapy; LIHC cis rs1728785 1.000 rs1728785 chr16:68591230 G/T cg02972257 chr16:68554789 NA 0.57 6.74 0.34 6.76e-11 Ulcerative colitis; LIHC trans rs837841 0.864 rs1660903 chr2:130046679 C/G cg08131848 chr9:88420837 LOC389765 0.36 6.06 0.31 3.57e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel); LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg10150615 chr22:24372951 LOC391322 -0.56 -8.33 -0.41 1.96e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg03517284 chr6:25882590 NA -0.68 -8.68 -0.42 1.67e-16 Intelligence (multi-trait analysis); LIHC cis rs4629710 0.592 rs9492864 chr6:131531306 A/T cg12606694 chr6:131520996 AKAP7 0.58 6.76 0.34 5.8e-11 Multiple myeloma (IgH translocation); LIHC cis rs5769765 0.862 rs9616380 chr22:50312225 T/C cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs7131987 0.868 rs11050151 chr12:29403008 T/A cg12903224 chr12:29470962 FAR2 -0.37 -5.97 -0.31 5.9e-9 QT interval; LIHC cis rs1953600 0.645 rs2573351 chr10:81931441 A/G cg27417294 chr10:81904244 PLAC9 0.35 6.03 0.31 4.37e-9 Sarcoidosis; LIHC cis rs72627123 0.867 rs8015927 chr14:74465756 A/T cg12022184 chr14:74485813 ENTPD5;C14orf45 -0.9 -8.3 -0.41 2.37e-15 Morning vs. evening chronotype; LIHC cis rs11676348 0.755 rs6436026 chr2:218951738 T/A cg00012203 chr2:219082015 ARPC2 -0.55 -7.67 -0.38 1.86e-13 Ulcerative colitis; LIHC cis rs7651039 0.641 rs2455823 chr3:15666856 T/C cg16303742 chr3:15540471 COLQ 0.4 6.48 0.33 3.29e-10 Coronary heart disease; LIHC cis rs748404 0.560 rs1060939 chr15:43816917 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.39 5.77 0.3 1.75e-8 Lung cancer; LIHC cis rs9814567 0.752 rs4318591 chr3:134328333 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.62 -0.46 1.53e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7633770 0.786 rs1402148 chr3:46678295 C/T cg11219411 chr3:46661640 NA 0.45 7.92 0.39 3.41e-14 Coronary artery disease; LIHC cis rs892961 0.932 rs9646396 chr17:75416755 G/A cg05865280 chr17:75406074 SEPT9 0.62 11.27 0.52 2.97e-25 Airflow obstruction; LIHC cis rs1570884 0.516 rs2094108 chr13:50171550 G/A cg08779649 chr13:50194554 NA 0.36 6.44 0.33 3.96e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs7131987 0.934 rs2216854 chr12:29423460 G/A cg21522988 chr12:29376872 FAR2 0.29 6.69 0.34 9.32e-11 QT interval; LIHC cis rs919433 1.000 rs1560277 chr2:198187903 C/T cg10820045 chr2:198174542 NA 0.56 9.33 0.45 1.41e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9560113 1.000 rs9560107 chr13:112180146 G/A cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs9733 0.525 rs11584184 chr1:150695689 A/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs66887589 0.837 rs6534135 chr4:120406302 A/G cg09307838 chr4:120376055 NA 0.5 7.68 0.38 1.73e-13 Diastolic blood pressure; LIHC cis rs79839061 0.656 rs28662837 chr4:879776 G/A cg07828340 chr4:882639 GAK 0.85 7.64 0.38 2.25e-13 Intelligence (multi-trait analysis); LIHC cis rs8072100 0.840 rs9895746 chr17:45479099 C/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.87 -0.3 1.03e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10927875 0.619 rs1806991 chr1:16129441 T/C cg21385522 chr1:16154831 NA -0.73 -10.26 -0.49 1.02e-21 Dilated cardiomyopathy; LIHC cis rs858239 0.508 rs7805071 chr7:23190212 C/T cg18081818 chr7:23246105 NA -0.39 -5.75 -0.3 1.95e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs311392 0.554 rs311387 chr8:55101623 A/G cg20636351 chr8:55087400 NA 0.29 5.93 0.31 7.36e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs7027203 1.000 rs7864114 chr9:96551954 A/G cg14598338 chr9:96623480 NA 0.32 6.21 0.32 1.56e-9 DNA methylation (variation); LIHC cis rs2404602 0.532 rs12591100 chr15:76700801 C/A cg23625390 chr15:77176239 SCAPER -0.41 -6.92 -0.35 2.23e-11 Blood metabolite levels; LIHC cis rs13161895 1.000 rs34674199 chr5:179473900 G/A cg06664874 chr5:179499304 RNF130 0.61 7.56 0.38 3.66e-13 LDL cholesterol; LIHC cis rs10791323 0.627 rs2723614 chr11:133705871 T/G cg06766960 chr11:133703094 NA -0.66 -10.76 -0.5 1.91e-23 Childhood ear infection; LIHC cis rs7131987 0.903 rs10843367 chr12:29408380 G/A cg00204748 chr12:29376779 FAR2 0.42 7.7 0.38 1.44e-13 QT interval; LIHC cis rs35306767 0.855 rs34251037 chr10:867884 C/T cg10556349 chr10:835070 NA 0.67 5.85 0.3 1.13e-8 Eosinophil percentage of granulocytes; LIHC cis rs9309473 0.687 rs6706409 chr2:73606508 G/T cg20560298 chr2:73613845 ALMS1 0.48 7.81 0.39 7.2e-14 Metabolite levels; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs6693567 0.565 rs1262432 chr1:150371839 C/A cg15654264 chr1:150340011 RPRD2 0.49 8.15 0.4 7.03e-15 Migraine; LIHC cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg27286337 chr10:134555280 INPP5A 0.93 13.32 0.58 6.93e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4654899 0.733 rs10799678 chr1:21322785 C/T cg08539965 chr1:21396338 EIF4G3 0.35 6.21 0.32 1.57e-9 Superior frontal gyrus grey matter volume; LIHC cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg10802521 chr3:52805072 NEK4 0.44 7.39 0.37 1.15e-12 Bipolar disorder; LIHC cis rs9715521 0.677 rs6822690 chr4:59853530 A/G cg11281224 chr4:60001000 NA -0.33 -6.34 -0.32 7.21e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs735396 0.770 rs1169301 chr12:121431300 C/T cg02403541 chr12:121454288 C12orf43 0.51 8.91 0.43 3.11e-17 N-glycan levels; LIHC cis rs16912285 0.688 rs7126291 chr11:24312936 A/C ch.11.24196551F chr11:24239977 NA 0.78 10.54 0.5 1.14e-22 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs8072100 1.000 rs11650372 chr17:45721795 G/A cg08085267 chr17:45401833 C17orf57 -0.57 -8.54 -0.42 4.49e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs73001065 0.688 rs59148799 chr19:19484008 A/G cg03709012 chr19:19516395 GATAD2A 0.94 10.27 0.49 9.84e-22 LDL cholesterol; LIHC cis rs5758511 0.514 rs5751211 chr22:42486056 G/A cg20195005 chr22:42527684 CYP2D6 0.32 6.15 0.32 2.19e-9 Birth weight; LIHC cis rs2976388 0.609 rs2717601 chr8:143807924 T/C cg06565975 chr8:143823917 SLURP1 0.34 6.65 0.34 1.17e-10 Urinary tract infection frequency; LIHC cis rs35110281 0.591 rs86138 chr21:44932398 G/A cg21573476 chr21:45109991 RRP1B -0.44 -7.98 -0.4 2.22e-14 Mean corpuscular volume; LIHC cis rs9486719 1.000 rs3798296 chr6:97052286 G/A cg18709589 chr6:96969512 KIAA0776 -0.51 -6.23 -0.32 1.39e-9 Migraine;Coronary artery disease; LIHC cis rs10193935 0.901 rs12620021 chr2:42477034 T/C cg27598129 chr2:42591480 NA -0.71 -10.3 -0.49 7.76e-22 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20174699 chr12:50222232 LOC100286844;NCKAP5L 0.48 6.79 0.34 5.08e-11 Lung function (FEV1/FVC); LIHC cis rs7582720 1.000 rs35212307 chr2:203765756 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7829975 0.540 rs2976909 chr8:8346690 C/T cg06636001 chr8:8085503 FLJ10661 -0.48 -6.7 -0.34 8.38e-11 Mood instability; LIHC cis rs35791980 0.560 rs4729347 chr7:76982480 C/T cg12876866 chr7:77025528 PION -0.46 -6.72 -0.34 7.51e-11 Pursuit maintenance gain; LIHC cis rs921968 0.541 rs12987171 chr2:219327030 G/C cg18887096 chr2:219472410 PLCD4 0.37 5.78 0.3 1.64e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs1577917 0.958 rs2100109 chr6:86544926 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.1 -0.4 9.8e-15 Response to antipsychotic treatment; LIHC cis rs965469 0.895 rs6051841 chr20:3392871 A/G cg25506879 chr20:3388711 C20orf194 -0.54 -6.31 -0.32 8.46e-10 IFN-related cytopenia; LIHC cis rs9649465 1.000 rs2109724 chr7:123325391 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.02e-15 Migraine; LIHC cis rs116095464 0.558 rs62346508 chr5:203668 T/C cg22857025 chr5:266934 NA -1.63 -16.46 -0.66 2.95e-45 Breast cancer; LIHC cis rs11098499 0.722 rs10025925 chr4:120271744 A/T cg09307838 chr4:120376055 NA 0.63 9.88 0.47 2.06e-20 Corneal astigmatism; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg13799429 chr6:90582589 CASP8AP2 0.59 6.08 0.31 3.12e-9 Mean platelet volume; LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg02475777 chr4:1388615 CRIPAK 0.51 7.56 0.38 3.76e-13 Longevity; LIHC cis rs1059312 1.000 rs1059312 chr12:129278864 A/G cg21616243 chr12:129299702 MGC16384;SLC15A4 0.69 13.3 0.58 8.38e-33 Systemic lupus erythematosus; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08078137 chr12:19593453 AEBP2 0.37 6.14 0.32 2.35e-9 Calcium levels; LIHC cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.46 -0.37 7.22e-13 Initial pursuit acceleration; LIHC cis rs950776 0.752 rs62010327 chr15:78892784 G/A cg06917634 chr15:78832804 PSMA4 0.65 8.77 0.43 8.85e-17 Sudden cardiac arrest; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23218665 chr1:11159850 EXOSC10 0.45 6.13 0.31 2.43e-9 Lung function (FEV1/FVC); LIHC cis rs1434579 0.572 rs926052 chr19:44952236 A/T cg15540054 chr19:45004280 ZNF180 0.63 9.81 0.47 3.63e-20 Tuberculosis; LIHC cis rs2228479 0.850 rs11076619 chr16:89831243 C/A cg19635926 chr16:89946313 TCF25 0.48 6.17 0.32 1.97e-9 Skin colour saturation; LIHC cis rs1003719 0.715 rs2835657 chr21:38565064 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.9 -0.51 6.09e-24 Eye color traits; LIHC cis rs3741404 0.620 rs2236648 chr11:63964657 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.75 11.99 0.54 6.58e-28 Platelet count; LIHC cis rs6466055 0.739 rs7806591 chr7:104927776 C/T cg04380332 chr7:105027541 SRPK2 0.37 6.86 0.35 3.2e-11 Schizophrenia; LIHC cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs4819041 chr21:46659955 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.48 6.92 0.35 2.26e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2727020 0.553 rs11040400 chr11:49518296 C/A cg15704280 chr7:45808275 SEPT13 -0.96 -19.36 -0.72 6.61e-57 Coronary artery disease; LIHC cis rs11077998 0.844 rs1109123 chr17:80522391 T/C cg10255544 chr17:80519551 FOXK2 0.49 8.84 0.43 5.32e-17 Reticulocyte fraction of red cells; LIHC cis rs11971779 0.680 rs4728465 chr7:139069061 G/A cg07862535 chr7:139043722 LUC7L2 0.64 11.08 0.51 1.44e-24 Diisocyanate-induced asthma; LIHC cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg17554472 chr22:41940697 POLR3H 0.54 5.93 0.31 7.29e-9 Vitiligo; LIHC cis rs4423214 1.000 rs4944959 chr11:71168234 C/T cg24826892 chr11:71159390 DHCR7 -0.46 -5.97 -0.31 5.8e-9 Vitamin D levels; LIHC cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg27286337 chr10:134555280 INPP5A 0.88 13.04 0.58 8.16e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg22105103 chr4:187893119 NA 0.34 8.48 0.42 7.07e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7577696 0.524 rs61399065 chr2:32208554 G/A cg02381751 chr2:32503542 YIPF4 -0.45 -6.13 -0.31 2.46e-9 Inflammatory biomarkers; LIHC cis rs1862618 0.671 rs2591966 chr5:56233688 T/G cg24531977 chr5:56204891 C5orf35 0.52 7.65 0.38 2.02e-13 Initial pursuit acceleration; LIHC cis rs6952808 0.594 rs3778964 chr7:2138109 C/T cg21782813 chr7:2030301 MAD1L1 0.38 6.5 0.33 2.76e-10 Bipolar disorder and schizophrenia; LIHC trans rs4718428 0.705 rs3800817 chr7:66263550 T/A cg10756647 chr7:56101905 PSPH 0.62 8.48 0.42 6.65e-16 Corneal structure; LIHC trans rs9747201 0.925 rs8072670 chr17:80159566 T/C cg07393940 chr7:158741817 NA 0.55 6.56 0.33 1.99e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2932538 0.922 rs12125361 chr1:113144779 C/T cg22162597 chr1:113214053 CAPZA1 0.72 11.13 0.52 9.27e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs4243830 0.522 rs11122086 chr1:6601246 T/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.92 -11.61 -0.53 1.71e-26 Body mass index; LIHC cis rs1552244 0.882 rs2130813 chr3:10038706 A/C cg00149659 chr3:10157352 C3orf10 0.52 5.98 0.31 5.66e-9 Alzheimer's disease; LIHC cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -5.84 -0.3 1.22e-8 Bipolar disorder and schizophrenia; LIHC cis rs96067 0.805 rs4652902 chr1:36612955 C/A cg24686825 chr1:36642396 MAP7D1 -0.56 -7.89 -0.39 4.18e-14 Corneal structure; LIHC cis rs7089973 0.604 rs10885618 chr10:116617718 A/G cg23260525 chr10:116636907 FAM160B1 0.39 7.71 0.38 1.4e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03864326 chr16:67927170 PSKH1 -0.49 -7.21 -0.36 3.73e-12 Cognitive function; LIHC cis rs425277 0.606 rs377283 chr1:2075570 T/C cg03732007 chr1:2071316 PRKCZ 0.34 5.73 0.3 2.23e-8 Height; LIHC cis rs4555082 0.874 rs1882846 chr14:105717448 G/C cg10792982 chr14:105748885 BRF1 0.46 6.25 0.32 1.24e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs459571 0.629 rs441233 chr9:136876021 A/G cg13789015 chr9:136890014 NCRNA00094 -0.33 -5.95 -0.31 6.48e-9 Platelet distribution width; LIHC cis rs7772486 0.686 rs9376961 chr6:146048737 C/T cg23711669 chr6:146136114 FBXO30 0.68 12.21 0.55 1.08e-28 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22529720 chr7:139044624 LUC7L2 -0.43 -6.32 -0.32 8.06e-10 Pancreatic cancer; LIHC cis rs7428 0.847 rs1969260 chr2:85568810 C/T cg27090078 chr2:85622094 CAPG -0.33 -5.79 -0.3 1.62e-8 Ear protrusion; LIHC trans rs1421898 0.509 rs62385365 chr5:158306962 G/A cg10462998 chr5:175976188 PCDH24 -0.71 -6.08 -0.31 3.22e-9 Inflammatory skin disease; LIHC cis rs9902453 0.845 rs7501472 chr17:28010628 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.48 0.53 4.98e-26 Coffee consumption (cups per day); LIHC cis rs7119038 0.818 rs6589685 chr11:118612197 T/C cg19308663 chr11:118741387 NA 0.4 6.27 0.32 1.08e-9 Sjögren's syndrome; LIHC cis rs561341 1.000 rs15654 chr17:30326360 A/C cg00745463 chr17:30367425 LRRC37B -0.77 -5.73 -0.3 2.16e-8 Hip circumference adjusted for BMI; LIHC trans rs526821 0.595 rs532278 chr11:55344983 A/G cg15704280 chr7:45808275 SEPT13 -0.52 -7.8 -0.39 7.82e-14 Pediatric bone mineral density (spine); LIHC trans rs10761482 0.500 rs2211220 chr10:62271491 A/G cg10096035 chr12:96392698 NA 0.4 6.36 0.33 6.28e-10 Schizophrenia; LIHC cis rs7945705 0.869 rs7925728 chr11:9013002 A/G cg12365402 chr11:9010492 NRIP3 -0.33 -8.58 -0.42 3.38e-16 Hemoglobin concentration; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg16189644 chr5:96271684 LNPEP -0.49 -7.45 -0.37 7.55e-13 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6598955 0.724 rs12132137 chr1:26631243 C/T cg04990556 chr1:26633338 UBXN11 -0.61 -9.72 -0.47 7.1e-20 Obesity-related traits; LIHC cis rs4555082 0.681 rs28588570 chr14:105709606 A/T cg06808227 chr14:105710500 BRF1 -0.62 -8.76 -0.43 9.03e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs6783573 0.683 rs3806702 chr3:46617502 T/C cg21489266 chr3:46619131 LRRC2;TDGF1 -0.45 -6.81 -0.35 4.27e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs9457247 0.663 rs2301436 chr6:167437988 C/T cg12798992 chr6:167411361 FGFR1OP 0.46 7.16 0.36 5.01e-12 Crohn's disease; LIHC trans rs11098499 0.535 rs10005542 chr4:120268302 T/C cg25214090 chr10:38739885 LOC399744 0.44 7.16 0.36 5.01e-12 Corneal astigmatism; LIHC trans rs1864585 0.552 rs73208794 chr8:10681248 C/G cg20373634 chr10:103911536 NOLC1 -0.47 -6.17 -0.32 1.93e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs7903847 0.642 rs1048442 chr10:99160152 A/G cg08345082 chr10:99160200 RRP12 -0.39 -6.63 -0.34 1.3e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs61990749 0.597 rs2267761 chr14:78147849 G/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.61 -10.15 -0.48 2.53e-21 Fibroblast growth factor basic levels; LIHC cis rs904251 0.797 rs1776460 chr6:37485484 A/G cg25019722 chr6:37503610 NA -0.37 -6.25 -0.32 1.24e-9 Cognitive performance; LIHC trans rs1814175 0.817 rs7927373 chr11:49957640 A/C cg18944383 chr4:111397179 ENPEP 0.27 7.06 0.36 9.34e-12 Height; LIHC cis rs67311347 1.000 rs6599102 chr3:40468406 G/A cg24209194 chr3:40518798 ZNF619 0.47 7.01 0.35 1.29e-11 Renal cell carcinoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11087358 chr12:57940980 DCTN2 0.4 6.27 0.32 1.11e-9 Cognitive function; LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg23978390 chr7:1156363 C7orf50 0.54 8.28 0.41 2.89e-15 Longevity;Endometriosis; LIHC cis rs6545883 0.894 rs2600672 chr2:61536740 A/G cg14146966 chr2:61757674 XPO1 0.44 7.39 0.37 1.13e-12 Tuberculosis; LIHC cis rs61712019 0.679 rs2204916 chr2:77730014 A/G cg11252801 chr2:77748917 LRRTM4 0.54 7.5 0.38 5.71e-13 Schizophrenia; LIHC cis rs1577917 0.740 rs2842604 chr6:86336300 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -12.25 -0.55 7.35e-29 Response to antipsychotic treatment; LIHC cis rs66887589 0.807 rs13134517 chr4:120405262 G/A cg09307838 chr4:120376055 NA 0.5 7.68 0.38 1.73e-13 Diastolic blood pressure; LIHC cis rs10751667 0.666 rs10794347 chr11:939863 G/A cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.56e-13 Alzheimer's disease (late onset); LIHC cis rs8081395 0.580 rs180515 chr17:58024275 A/G cg13753209 chr17:57696993 CLTC 0.49 7.79 0.39 7.91e-14 White blood cell count; LIHC cis rs870825 0.616 rs6552806 chr4:185638231 C/T cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC cis rs7552404 0.731 rs1770885 chr1:76402212 C/T cg03433033 chr1:76189801 ACADM -0.55 -6.62 -0.34 1.4e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8180040 0.593 rs4018905 chr3:47138170 A/G cg27129171 chr3:47204927 SETD2 0.57 9.41 0.45 7.47e-19 Colorectal cancer; LIHC cis rs8141529 0.673 rs132548 chr22:29317559 C/G cg02153584 chr22:29168773 CCDC117 -0.51 -7.92 -0.39 3.26e-14 Lymphocyte counts; LIHC cis rs523522 0.885 rs524735 chr12:121022099 T/C cg12219531 chr12:120966889 COQ5 0.68 13.23 0.58 1.46e-32 High light scatter reticulocyte count; LIHC cis rs10752881 1.000 rs12403189 chr1:182983832 G/C ch.1.3577855R chr1:183094577 LAMC1 0.58 10.09 0.48 4.09e-21 Colorectal cancer; LIHC cis rs10504073 0.669 rs341799 chr8:50036574 A/G cg00325661 chr8:49890786 NA 0.32 7.25 0.36 2.89e-12 Blood metabolite ratios; LIHC cis rs7666738 0.606 rs4637413 chr4:99088151 A/G cg05340658 chr4:99064831 C4orf37 0.65 11.68 0.53 9.06e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs2439831 1.000 rs2245790 chr15:43744457 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.73 0.43 1.12e-16 Lung cancer in ever smokers; LIHC cis rs9868809 0.505 rs28657585 chr3:48736216 A/T cg07636037 chr3:49044803 WDR6 -0.7 -7.35 -0.37 1.49e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs919433 0.617 rs700642 chr2:198600730 G/T cg10820045 chr2:198174542 NA -0.47 -7.22 -0.36 3.29e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2072499 0.966 rs2984615 chr1:156165317 G/C cg24450063 chr1:156163899 SLC25A44 1.08 18.76 0.71 1.68e-54 Testicular germ cell tumor; LIHC cis rs7552404 0.765 rs1251078 chr1:76189488 C/G cg03433033 chr1:76189801 ACADM -0.78 -18.21 -0.7 2.89e-52 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2236521 0.659 rs72487383 chr20:60889313 A/C cg09594475 chr20:60884601 LAMA5 0.58 9.64 0.46 1.26e-19 Pelvic organ prolapse; LIHC cis rs10791097 0.694 rs4459316 chr11:130756176 T/C cg22079354 chr11:130786696 SNX19 0.41 5.82 0.3 1.35e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg05025164 chr4:1340916 KIAA1530 0.44 6.37 0.33 5.98e-10 Longevity; LIHC trans rs1005277 0.579 rs1780137 chr10:38501475 C/G cg27523141 chr10:43048294 ZNF37B 0.38 6.34 0.32 7.43e-10 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg07677032 chr17:61819896 STRADA 0.42 6.2 0.32 1.61e-9 Prudent dietary pattern; LIHC cis rs9902453 0.765 rs9890747 chr17:28007442 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.22 0.58 1.62e-32 Coffee consumption (cups per day); LIHC trans rs9929218 1.000 rs9929218 chr16:68820946 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.46 -0.42 7.82e-16 Colorectal cancer; LIHC cis rs7523273 0.565 rs2796250 chr1:207903654 T/C cg22525895 chr1:207977042 MIR29B2 -0.55 -8.32 -0.41 2.11e-15 Schizophrenia; LIHC cis rs9303401 0.625 rs66508449 chr17:56691034 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.5 0.59 1.38e-33 Cognitive test performance; LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg07308232 chr7:1071921 C7orf50 -0.38 -6.07 -0.31 3.44e-9 Longevity;Endometriosis; LIHC cis rs17125944 0.505 rs2274275 chr14:53235728 G/T cg13660082 chr14:53194042 PSMC6 -0.46 -7.54 -0.38 4.22e-13 Alzheimer's disease (late onset); LIHC cis rs483180 0.532 rs561931 chr1:120254506 A/G cg19096424 chr1:120255104 PHGDH 0.68 8.74 0.43 1.06e-16 Macular telangiectasia type 2; LIHC cis rs769267 0.929 rs2905424 chr19:19473445 T/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.59 -9.12 -0.44 6.57e-18 Tonsillectomy; LIHC cis rs12594515 0.967 rs8039088 chr15:45990178 T/C cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC cis rs1419980 0.730 rs11054884 chr12:7772906 A/T cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs9457247 0.967 rs430145 chr6:167410369 C/T cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC cis rs3008870 0.755 rs2755242 chr1:67479598 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.64 10.73 0.5 2.41e-23 Lymphocyte percentage of white cells; LIHC cis rs7903847 0.642 rs7088410 chr10:99135539 G/T cg20016023 chr10:99160130 RRP12 -0.41 -6.48 -0.33 3.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs4700695 0.545 rs29441 chr5:65509116 G/T cg21114390 chr5:65439923 SFRS12 -0.53 -7.73 -0.39 1.24e-13 Facial morphology (factor 19); LIHC cis rs1023500 0.505 rs134885 chr22:42673811 C/G cg00645731 chr22:42541494 CYP2D7P1 0.35 6.15 0.32 2.15e-9 Schizophrenia; LIHC cis rs763014 0.966 rs35642938 chr16:642249 T/C cg09256448 chr16:638327 NA 0.39 6.66 0.34 1.1e-10 Height; LIHC trans rs8117834 0.574 rs6108106 chr20:8086361 G/A cg00593689 chr4:53575888 NA 0.38 6.44 0.33 3.98e-10 Chronic kidney disease; LIHC cis rs10857712 0.904 rs2265641 chr10:135221869 G/A cg01444801 chr10:135216882 MTG1 0.66 9.88 0.47 2.12e-20 Systemic lupus erythematosus; LIHC cis rs34779708 0.966 rs4934539 chr10:35472199 A/G cg04310649 chr10:35416472 CREM -0.43 -5.85 -0.3 1.13e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg10862848 chr6:42927986 GNMT -0.29 -6.73 -0.34 7.11e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9902453 0.765 rs2729440 chr17:28106874 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs4555082 0.874 rs113291192 chr14:105738181 C/T cg10792982 chr14:105748885 BRF1 0.45 6.04 0.31 3.97e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs6089584 0.854 rs6061985 chr20:60622362 T/C cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs6547741 0.967 rs4665999 chr2:27834444 T/C cg27432699 chr2:27873401 GPN1 0.71 11.58 0.53 2.17e-26 Oral cavity cancer; LIHC cis rs2257205 0.667 rs7207254 chr17:56912572 C/T cg05425664 chr17:57184151 TRIM37 -0.61 -6.13 -0.31 2.36e-9 Pancreatic cancer; LIHC cis rs208520 0.754 rs1100989 chr6:66880532 G/A cg07460842 chr6:66804631 NA -0.79 -8.82 -0.43 5.87e-17 Exhaled nitric oxide output; LIHC cis rs941408 0.515 rs1005556 chr19:2778543 G/T cg02580895 chr19:2754563 NA -0.46 -6.86 -0.35 3.14e-11 Total cholesterol levels; LIHC cis rs4660306 0.614 rs11211116 chr1:45930038 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.63 6.68 0.34 9.58e-11 Homocysteine levels; LIHC trans rs2727020 0.576 rs10839305 chr11:49598733 T/C cg03929089 chr4:120376271 NA -0.9 -17.93 -0.7 3.7700000000000003e-51 Coronary artery disease; LIHC cis rs238295 0.805 rs1053399 chr20:5525986 T/C cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -6.95 -0.35 1.89e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg00800038 chr16:89945340 TCF25 -0.59 -9.64 -0.46 1.28e-19 Skin colour saturation; LIHC trans rs9388451 0.874 rs13209968 chr6:126089285 G/C cg05039488 chr6:79577232 IRAK1BP1 -0.56 -8.91 -0.43 3.16e-17 Brugada syndrome; LIHC trans rs12753920 0.642 rs2209337 chr1:92623079 C/G cg15668468 chr10:118892869 VAX1 0.43 6.11 0.31 2.72e-9 Systemic lupus erythematosus; LIHC cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg18252515 chr7:66147081 NA 1.29 17.4 0.69 4.95e-49 Diabetic kidney disease; LIHC cis rs1691799 0.867 rs1027401 chr12:66760892 C/G cg16791601 chr12:66731901 HELB -0.48 -10.29 -0.49 8.26e-22 White blood cell count (basophil); LIHC cis rs7927592 0.731 rs10896350 chr11:68386373 A/C cg16797656 chr11:68205561 LRP5 0.51 8.89 0.43 3.66e-17 Total body bone mineral density; LIHC cis rs9916302 0.904 rs4794814 chr17:37696852 G/A cg03013999 chr17:37608204 MED1 0.35 5.78 0.3 1.71e-8 Glomerular filtration rate (creatinine); LIHC cis rs4974559 0.501 rs1732115 chr4:1244416 C/T cg02980000 chr4:1222292 CTBP1 0.8 6.06 0.31 3.67e-9 Systolic blood pressure; LIHC cis rs12701220 0.817 rs7798459 chr7:1087965 C/T cg26769984 chr7:1090371 C7orf50 0.56 7.46 0.37 7.29e-13 Bronchopulmonary dysplasia; LIHC cis rs1707322 0.964 rs785509 chr1:46527300 G/A cg03146154 chr1:46216737 IPP -0.45 -7.4 -0.37 1.03e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg12053284 chr18:40857256 SYT4 -0.52 -6.17 -0.32 1.95e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs8141529 0.956 rs469989 chr22:29303595 G/C cg15103426 chr22:29168792 CCDC117 -0.46 -7.24 -0.36 2.99e-12 Lymphocyte counts; LIHC cis rs35110281 0.837 rs2838341 chr21:45076443 A/G cg01579765 chr21:45077557 HSF2BP -0.31 -6.05 -0.31 3.76e-9 Mean corpuscular volume; LIHC cis rs9905704 0.647 rs33922512 chr17:57114148 C/G cg12560992 chr17:57184187 TRIM37 -0.66 -9.85 -0.47 2.49e-20 Testicular germ cell tumor; LIHC cis rs826838 0.967 rs826879 chr12:39088999 A/C cg26384229 chr12:38710491 ALG10B -0.6 -8.93 -0.43 2.69e-17 Heart rate; LIHC cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg18404041 chr3:52824283 ITIH1 -0.48 -8.03 -0.4 1.64e-14 Electroencephalogram traits; LIHC cis rs7572733 0.555 rs2342558 chr2:198920142 T/C cg00792783 chr2:198669748 PLCL1 0.42 6.05 0.31 3.81e-9 Dermatomyositis; LIHC cis rs8056893 0.714 rs1868159 chr16:68387496 G/T cg02226672 chr16:68398533 SMPD3 -0.45 -6.22 -0.32 1.42e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs921968 0.612 rs496908 chr2:219357742 A/T cg18887096 chr2:219472410 PLCD4 0.37 6.34 0.32 7.16e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs17253792 0.822 rs78615025 chr14:56168012 G/A cg01858014 chr14:56050164 KTN1 -0.7 -7.28 -0.37 2.26e-12 Putamen volume; LIHC cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3741798 1.000 rs61922049 chr12:12497395 C/T cg08615371 chr12:12503544 MANSC1 0.91 7.34 0.37 1.54e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg06634786 chr22:41940651 POLR3H -0.79 -8.69 -0.43 1.55e-16 Vitiligo; LIHC cis rs9296092 0.538 rs62407566 chr6:33535786 C/T cg13560919 chr6:33536144 NA -0.41 -6.27 -0.32 1.11e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs722599 0.599 rs8003660 chr14:75227098 T/C cg11812906 chr14:75593930 NEK9 0.41 6.32 0.32 8.3e-10 IgG glycosylation; LIHC cis rs17376456 0.569 rs2045020 chr5:93224466 T/C cg25358565 chr5:93447407 FAM172A -0.82 -7.95 -0.4 2.7e-14 Diabetic retinopathy; LIHC cis rs6429082 0.791 rs61836205 chr1:235638753 C/G cg26050004 chr1:235667680 B3GALNT2 0.49 7.44 0.37 7.99e-13 Adiposity; LIHC cis rs7927592 0.913 rs2236708 chr11:68378045 G/A cg20283391 chr11:68216788 NA -0.52 -7.7 -0.38 1.43e-13 Total body bone mineral density; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg14709524 chr16:89940631 TCF25 -0.54 -7.45 -0.37 7.48e-13 Skin colour saturation; LIHC trans rs17685 0.515 rs111240556 chr7:75600863 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 7.9 0.39 3.87e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1043515 0.642 rs8592 chr17:36958065 A/G cg09592244 chr17:37024020 NA 0.36 5.98 0.31 5.56e-9 Height; LIHC cis rs2380220 0.574 rs9400526 chr6:95998441 T/C cg23517279 chr6:96025343 MANEA 0.54 6.03 0.31 4.26e-9 Behavioural disinhibition (generation interaction); LIHC cis rs2439831 1.000 rs2264239 chr15:43765533 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.79 0.43 7.64e-17 Lung cancer in ever smokers; LIHC cis rs155076 1.000 rs261430 chr13:21865242 C/T cg11317459 chr13:21872234 NA -1.13 -12.63 -0.56 2.88e-30 White matter hyperintensity burden; LIHC cis rs35306767 0.715 rs1871622 chr10:1049309 T/G cg26597838 chr10:835615 NA 0.9 8.69 0.43 1.54e-16 Eosinophil percentage of granulocytes; LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg10755058 chr3:40428713 ENTPD3 0.4 6.88 0.35 2.79e-11 Renal cell carcinoma; LIHC cis rs7598759 0.548 rs6750795 chr2:232378231 T/C cg19187155 chr2:232395269 NMUR1 0.59 9.01 0.44 1.48e-17 Noise-induced hearing loss; LIHC cis rs11098499 0.866 rs10518329 chr4:120401835 A/G cg09307838 chr4:120376055 NA 0.69 11.15 0.52 8.1e-25 Corneal astigmatism; LIHC trans rs7980799 0.682 rs7138529 chr12:33634855 T/C cg26384229 chr12:38710491 ALG10B -0.46 -6.14 -0.32 2.23e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs7188697 0.922 rs37041 chr16:58579886 T/C cg02549819 chr16:58548995 SETD6 -0.46 -7.28 -0.37 2.35e-12 QT interval; LIHC cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg12310025 chr6:25882481 NA -0.61 -8.89 -0.43 3.66e-17 Blood metabolite levels; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg21384971 chr17:46114574 COPZ2;MIR152 -0.51 -6.84 -0.35 3.67e-11 Lung cancer in ever smokers; LIHC cis rs3793683 0.825 rs3793674 chr10:134555773 C/T cg26818010 chr10:134567672 INPP5A 0.62 8.4 0.41 1.21e-15 Migraine; LIHC cis rs7264396 0.563 rs2425138 chr20:34345710 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -6.53 -0.33 2.39e-10 Total cholesterol levels; LIHC cis rs9640161 0.659 rs7806429 chr7:150013393 A/G cg21361702 chr7:150065534 REPIN1 0.47 6.66 0.34 1.12e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs1256061 0.646 rs1256056 chr14:64712626 A/G cg23250157 chr14:64679961 SYNE2 0.39 5.8 0.3 1.47e-8 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7534824 0.625 rs12561853 chr1:101457863 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.67 -7.85 -0.39 5.43e-14 Refractive astigmatism; LIHC cis rs4660306 0.961 rs945179 chr1:45992460 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.65 7.78 0.39 8.4e-14 Homocysteine levels; LIHC cis rs67460515 0.596 rs4856700 chr3:160922951 A/C cg03342759 chr3:160939853 NMD3 -0.6 -8.81 -0.43 6.19e-17 Parkinson's disease; LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg14393609 chr7:65229607 NA -0.39 -6.52 -0.33 2.46e-10 Calcium levels; LIHC cis rs2153535 0.580 rs5001324 chr6:8451604 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC cis rs8062405 0.690 rs7187604 chr16:28565953 A/G cg16576597 chr16:28551801 NUPR1 0.48 7.53 0.38 4.68e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg03806693 chr22:41940476 POLR3H -1.06 -11.64 -0.53 1.36e-26 Vitiligo; LIHC cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg00750074 chr16:89608354 SPG7 -0.53 -8.58 -0.42 3.31e-16 Multiple myeloma (IgH translocation); LIHC cis rs7909074 0.798 rs10900126 chr10:45386322 G/T cg04218760 chr10:45406644 TMEM72 -0.24 -7.47 -0.37 6.94e-13 Mean corpuscular volume; LIHC cis rs9918079 0.560 rs7438356 chr4:15624770 C/T cg16509355 chr4:15471240 CC2D2A -0.47 -7.59 -0.38 2.98e-13 Obesity-related traits; LIHC cis rs826838 0.809 rs11169666 chr12:39211300 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.96 0.31 6.39e-9 Heart rate; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg20990694 chr7:150417431 GIMAP1 0.37 6.14 0.32 2.24e-9 Electroencephalogram traits; LIHC cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg00280220 chr17:61926910 NA 0.42 6.76 0.34 6e-11 Prudent dietary pattern; LIHC cis rs903552 0.736 rs9806495 chr15:102008059 G/A cg00659931 chr15:102010125 PCSK6 -0.52 -7.0 -0.35 1.32e-11 Diabetic kidney disease; LIHC cis rs66887589 0.967 rs59516282 chr4:120502016 G/A cg09307838 chr4:120376055 NA -0.5 -7.5 -0.38 5.59e-13 Diastolic blood pressure; LIHC cis rs875971 0.756 rs4718328 chr7:65693337 A/G cg11764359 chr7:65958608 NA -0.82 -13.9 -0.6 4.01e-35 Aortic root size; LIHC cis rs10845606 0.581 rs9971854 chr12:12834186 A/G cg09462578 chr12:12878428 APOLD1 0.46 6.74 0.34 6.71e-11 Systemic lupus erythematosus; LIHC cis rs4665809 1.000 rs3910272 chr2:26287842 T/A cg26119090 chr2:26468346 HADHA;HADHB -0.77 -9.42 -0.45 6.74e-19 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs4243830 0.850 rs4434862 chr1:6602241 C/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.95 -12.12 -0.55 2.25e-28 Body mass index; LIHC cis rs7089973 0.604 rs7914792 chr10:116591391 T/C cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2742417 0.603 rs2742370 chr3:45782098 T/C cg04837898 chr3:45731254 SACM1L -0.51 -8.47 -0.42 7.25e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 8.74 0.43 1.09e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg00684032 chr4:1343700 KIAA1530 0.36 5.94 0.31 7.06e-9 Obesity-related traits; LIHC cis rs2797160 0.904 rs1739370 chr6:126011231 C/T cg05901451 chr6:126070800 HEY2 0.48 7.99 0.4 2.04e-14 Endometrial cancer; LIHC cis rs9399135 1.000 rs11754265 chr6:135356216 C/G cg22676075 chr6:135203613 NA 0.39 6.32 0.32 7.94e-10 Red blood cell count; LIHC cis rs35306767 0.951 rs11253530 chr10:993729 T/C cg26597838 chr10:835615 NA 1.02 10.16 0.48 2.32e-21 Eosinophil percentage of granulocytes; LIHC cis rs317689 0.581 rs315132 chr12:69761996 G/C cg14784868 chr12:69753453 YEATS4 0.85 16.21 0.66 2.92e-44 Response to diuretic therapy; LIHC cis rs9733 0.519 rs10788792 chr1:150638572 T/G cg15448220 chr1:150897856 SETDB1 0.43 6.73 0.34 6.96e-11 Tonsillectomy; LIHC cis rs7116495 0.609 rs1541304 chr11:71714078 T/C cg10381502 chr11:71823885 C11orf51 -1.06 -9.3 -0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs6582630 0.555 rs10785443 chr12:38463792 A/C cg13010199 chr12:38710504 ALG10B 0.43 5.8 0.3 1.54e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs427394 0.659 rs274695 chr5:6732252 G/C cg10857441 chr5:6722123 POLS -0.38 -6.45 -0.33 3.89e-10 Menopause (age at onset); LIHC cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg08923669 chr16:420230 MRPL28 -0.54 -8.22 -0.41 4.33e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs941873 0.868 rs7332 chr10:81114060 G/A cg11057378 chr10:81107060 PPIF 0.37 6.06 0.31 3.63e-9 Height; LIHC cis rs10508774 1.000 rs72795567 chr10:32896509 T/C cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9818758 0.607 rs9847839 chr3:49289003 T/C cg00383909 chr3:49044727 WDR6 0.8 6.81 0.35 4.29e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6733011 0.578 rs10172158 chr2:99509605 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.45 -6.44 -0.33 3.95e-10 Bipolar disorder; LIHC cis rs12765878 1.000 rs11191849 chr10:105650880 T/A cg11005552 chr10:105648138 OBFC1 0.39 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs9399137 0.507 rs6940258 chr6:135366132 C/T cg24558204 chr6:135376177 HBS1L 0.63 10.68 0.5 3.48e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs1670533 1.000 rs6837145 chr4:1071067 T/C cg27284194 chr4:1044797 NA 0.61 9.13 0.44 6.16e-18 Recombination rate (females); LIHC cis rs2274273 0.901 rs17674563 chr14:55831125 G/A cg01864836 chr14:55583639 NA -0.38 -6.58 -0.34 1.72e-10 Protein biomarker; LIHC cis rs3859192 0.599 rs34933056 chr17:38162983 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.91 0.65 4.82e-43 White blood cell count; LIHC cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.89 0.57 2.95e-31 Alzheimer's disease; LIHC cis rs6701037 1.000 rs6701037 chr1:175120079 G/T cg17845761 chr1:175162550 KIAA0040 0.36 5.99 0.31 5.36e-9 Alcohol dependence; LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 25.04 0.8 2.33e-79 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs7582720 1.000 rs72926787 chr2:203818299 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02257712 chr5:150080478 RBM22 0.44 6.1 0.31 2.85e-9 Pancreatic cancer; LIHC cis rs7617773 0.743 rs11716371 chr3:48362750 C/T cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC trans rs561341 1.000 rs8070262 chr17:30262467 A/G cg20587970 chr11:113659929 NA -0.58 -6.74 -0.34 6.58e-11 Hip circumference adjusted for BMI; LIHC cis rs7528419 0.895 rs1277930 chr1:109822143 G/A cg00908766 chr1:109817496 CELSR2 0.46 8.2 0.41 4.95e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs6754311 0.731 rs2322660 chr2:136557319 A/G cg25344623 chr2:136566232 LCT -0.41 -8.45 -0.42 8.43e-16 Mosquito bite size; LIHC trans rs3213545 0.700 rs2260445 chr12:121468863 C/A cg01148741 chr2:96811453 DUSP2 -0.39 -6.3 -0.32 9.41e-10 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs3096299 0.900 rs744327 chr16:89439270 C/T cg01788221 chr16:89496183 ANKRD11 -0.42 -6.48 -0.33 3.14e-10 Multiple myeloma (IgH translocation); LIHC cis rs875971 0.545 rs316305 chr7:65617971 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.37 -7.5 -0.38 5.5e-13 Aortic root size; LIHC cis rs9309473 0.847 rs13538 chr2:73868328 A/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.51 -0.33 2.64e-10 Metabolite levels; LIHC cis rs9377188 0.744 rs2486419 chr6:149329771 G/T cg03945663 chr6:149309952 UST 0.26 6.0 0.31 4.97e-9 Cancer; LIHC cis rs28493229 0.522 rs2233152 chr19:41281016 C/T cg21869046 chr19:41225005 ITPKC 0.42 5.87 0.3 1.03e-8 Kawasaki disease; LIHC cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg12463550 chr7:65579703 CRCP 0.68 7.11 0.36 6.92e-12 Diabetic kidney disease; LIHC cis rs28374715 0.662 rs522063 chr15:41476209 A/G cg18705301 chr15:41695430 NDUFAF1 0.8 9.43 0.45 6.45e-19 Ulcerative colitis; LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg23782820 chr8:58130467 NA 0.34 5.85 0.3 1.13e-8 Developmental language disorder (linguistic errors); LIHC cis rs17376456 0.877 rs10040648 chr5:93490301 G/C cg25358565 chr5:93447407 FAM172A 1.03 9.27 0.45 2.19e-18 Diabetic retinopathy; LIHC cis rs55665837 0.502 rs4757269 chr11:14836192 A/C cg16394018 chr11:14927549 NA 0.4 5.81 0.3 1.39e-8 Vitamin D levels; LIHC cis rs11673344 0.864 rs2263167 chr19:37520927 A/G cg27390819 chr19:37464633 NA -0.52 -6.34 -0.32 7.35e-10 Obesity-related traits; LIHC cis rs9303401 0.614 rs34941454 chr17:57102742 T/G cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.81 0.54 3.03e-27 Cognitive test performance; LIHC cis rs12477438 0.520 rs6542864 chr2:99725223 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.2 21.33 0.76 8.61e-65 Chronic sinus infection; LIHC cis rs5769765 0.908 rs9616216 chr22:50318927 T/C cg02269571 chr22:50332266 NA -0.66 -9.07 -0.44 9.22e-18 Schizophrenia; LIHC cis rs4423214 1.000 rs2040323 chr11:71172783 A/C cg24826892 chr11:71159390 DHCR7 0.47 6.01 0.31 4.84e-9 Vitamin D levels; LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg26338869 chr17:61819248 STRADA 0.6 8.83 0.43 5.67e-17 Prudent dietary pattern; LIHC cis rs3008870 0.755 rs6657065 chr1:67384639 T/G cg02640540 chr1:67518911 SLC35D1 0.41 6.42 0.33 4.48e-10 Lymphocyte percentage of white cells; LIHC cis rs6582630 0.537 rs11611326 chr12:38547958 C/A cg13010199 chr12:38710504 ALG10B 0.58 6.93 0.35 2.09e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs4474465 0.646 rs7937417 chr11:78284470 A/G cg27205649 chr11:78285834 NARS2 0.51 7.93 0.39 3.04e-14 Alzheimer's disease (survival time); LIHC cis rs780096 0.526 rs7602534 chr2:27592423 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.4 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs11122272 0.735 rs2790892 chr1:231512771 G/A cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.09e-18 Hemoglobin concentration; LIHC cis rs826838 0.838 rs11183646 chr12:38799846 A/T cg26384229 chr12:38710491 ALG10B 1.06 14.27 0.61 1.46e-36 Heart rate; LIHC cis rs9517320 0.534 rs9556963 chr13:99157026 G/A cg07423050 chr13:99094983 FARP1 -0.49 -8.69 -0.43 1.55e-16 Longevity; LIHC cis rs11148252 0.846 rs7985262 chr13:52997161 C/T cg00495681 chr13:53174319 NA 0.39 6.46 0.33 3.68e-10 Lewy body disease; LIHC cis rs910316 0.699 rs175039 chr14:75468950 G/C cg08847533 chr14:75593920 NEK9 -0.86 -16.93 -0.68 3.93e-47 Height; LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs950776 0.518 rs3813571 chr15:78832792 G/T cg22563815 chr15:78856949 CHRNA5 0.37 6.79 0.34 5.04e-11 Sudden cardiac arrest; LIHC cis rs5769765 0.908 rs4074304 chr22:50309446 G/A cg26441486 chr22:50317300 CRELD2 0.36 5.73 0.3 2.16e-8 Schizophrenia; LIHC cis rs9296092 0.517 rs3912041 chr6:33521271 T/C cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs703842 1.000 rs703842 chr12:58162739 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.82 -13.76 -0.6 1.32e-34 Multiple sclerosis; LIHC cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg06453172 chr10:134556979 INPP5A -0.63 -8.09 -0.4 1.05e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6684514 0.961 rs12048077 chr1:156299916 T/A cg16558208 chr1:156270281 VHLL 0.54 10.34 0.49 5.34e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1559088 0.576 rs7251626 chr19:33578470 C/A cg17764715 chr19:33622953 WDR88 0.6 8.26 0.41 3.12e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs6598955 0.671 rs58038522 chr1:26582713 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg05368731 chr17:41323189 NBR1 0.72 12.43 0.56 1.65e-29 Menopause (age at onset); LIHC cis rs870825 0.860 rs72703527 chr4:185605997 C/A cg04058563 chr4:185651563 MLF1IP 0.84 6.96 0.35 1.73e-11 Blood protein levels; LIHC cis rs7412746 0.658 rs3843843 chr1:150918084 C/T cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg22963979 chr7:1858916 MAD1L1 0.42 6.72 0.34 7.81e-11 Bipolar disorder and schizophrenia; LIHC cis rs7208859 0.623 rs73271869 chr17:29152221 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.0 0.4 1.97e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg07092213 chr7:1199455 ZFAND2A -0.48 -7.41 -0.37 1e-12 Longevity;Endometriosis; LIHC cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.11 -15.49 -0.64 2.29e-41 Gut microbiome composition (summer); LIHC cis rs9814567 1.000 rs62271515 chr3:134300507 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.09 -0.55 2.98e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6088590 1.000 rs6120708 chr20:33335526 G/A cg06115741 chr20:33292138 TP53INP2 0.59 8.42 0.41 1.08e-15 Coronary artery disease; LIHC cis rs8067545 0.750 rs918228 chr17:20002012 C/T cg13482628 chr17:19912719 NA 0.49 7.98 0.4 2.24e-14 Schizophrenia; LIHC cis rs7914558 0.933 rs2066323 chr10:104871361 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7833790 0.700 rs7834483 chr8:82704828 A/G cg17211192 chr8:82754475 SNX16 -0.52 -9.3 -0.45 1.7e-18 Diastolic blood pressure; LIHC cis rs477692 0.905 rs544217 chr10:131420584 A/G cg05714579 chr10:131428358 MGMT 0.48 8.16 0.4 6.3e-15 Response to temozolomide; LIHC cis rs7582180 0.606 rs10174145 chr2:100932488 T/C cg14675211 chr2:100938903 LONRF2 0.56 8.7 0.43 1.44e-16 Intelligence (multi-trait analysis); LIHC cis rs1559088 0.948 rs9304844 chr19:33579935 G/T cg27124370 chr19:33622961 WDR88 0.54 8.71 0.43 1.3e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.91 0.57 2.5e-31 Prudent dietary pattern; LIHC cis rs4808199 0.947 rs754255 chr19:19578890 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.42 5.94 0.31 7.05e-9 Nonalcoholic fatty liver disease; LIHC cis rs9394841 0.692 rs34073739 chr6:41829970 A/G cg08135965 chr6:41755394 TOMM6 0.45 5.95 0.31 6.46e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.84 0.35 3.58e-11 Cognitive function; LIHC cis rs7772486 0.754 rs1415746 chr6:146077107 A/G cg05347473 chr6:146136440 FBXO30 -0.41 -6.68 -0.34 9.73e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs6701037 0.566 rs13373754 chr1:175139275 C/A cg00958927 chr1:175162553 KIAA0040 0.39 6.51 0.33 2.67e-10 Alcohol dependence; LIHC cis rs2574704 1.000 rs11711892 chr3:11650787 T/C cg15876825 chr3:11651881 VGLL4 -0.49 -8.2 -0.41 4.95e-15 Body mass index; LIHC cis rs1023500 0.552 rs5758566 chr22:42454354 G/A cg04733989 chr22:42467013 NAGA 0.66 9.5 0.46 3.9e-19 Schizophrenia; LIHC cis rs9467773 0.526 rs3734536 chr6:26365346 C/G cg14345882 chr6:26364793 BTN3A2 0.34 5.73 0.3 2.23e-8 Intelligence (multi-trait analysis); LIHC trans rs875971 0.830 rs7799834 chr7:65880694 A/C cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs8141529 0.748 rs132533 chr22:29299571 A/G cg02153584 chr22:29168773 CCDC117 -0.51 -8.0 -0.4 1.99e-14 Lymphocyte counts; LIHC cis rs6754311 0.731 rs7569057 chr2:136583958 A/C cg25344623 chr2:136566232 LCT -0.4 -8.15 -0.4 7.08e-15 Mosquito bite size; LIHC cis rs752010 0.714 rs7515948 chr1:42079046 T/G cg06885757 chr1:42089581 HIVEP3 0.3 6.37 0.33 6.14e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs11711311 1.000 rs10934243 chr3:113430239 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.33 -0.37 1.67e-12 IgG glycosylation; LIHC cis rs9818758 0.607 rs11710247 chr3:49249800 G/T cg00383909 chr3:49044727 WDR6 0.81 6.76 0.34 6.07e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6840360 0.615 rs12503677 chr4:152610543 A/G cg22705602 chr4:152727874 NA -0.35 -7.27 -0.37 2.4e-12 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.36 0.56 3.01e-29 Prudent dietary pattern; LIHC cis rs7100689 0.577 rs873395 chr10:82037215 C/T cg00277334 chr10:82204260 NA 0.49 5.96 0.31 6.26e-9 Post bronchodilator FEV1; LIHC cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.38 0.33 5.67e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg09455208 chr3:40491958 NA -0.39 -7.8 -0.39 7.81e-14 Renal cell carcinoma; LIHC cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg02187348 chr16:89574699 SPG7 0.62 9.88 0.47 2.05e-20 Multiple myeloma (IgH translocation); LIHC cis rs13223928 0.621 rs4722440 chr7:3155901 C/T cg19214707 chr7:3157722 NA 0.44 8.36 0.41 1.63e-15 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs903552 1.000 rs4965872 chr15:102004002 C/T cg25677261 chr15:102009856 PCSK6 -0.46 -6.19 -0.32 1.68e-9 Diabetic kidney disease; LIHC cis rs736408 0.812 rs4687654 chr3:52827566 G/A cg18404041 chr3:52824283 ITIH1 -0.63 -10.36 -0.49 4.75e-22 Bipolar disorder; LIHC cis rs6570726 0.764 rs9403733 chr6:145912311 A/C cg23711669 chr6:146136114 FBXO30 0.73 12.31 0.55 4.35e-29 Lobe attachment (rater-scored or self-reported); LIHC trans rs875971 0.540 rs35510581 chr7:65578777 G/A cg26939375 chr7:64535504 NA -0.45 -6.87 -0.35 3.05e-11 Aortic root size; LIHC cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg18867708 chr6:26865862 GUSBL1 -0.57 -8.61 -0.42 2.71e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg10802521 chr3:52805072 NEK4 -0.44 -7.29 -0.37 2.16e-12 Bipolar disorder; LIHC cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg07092213 chr7:1199455 ZFAND2A -0.44 -6.45 -0.33 3.83e-10 Longevity;Endometriosis; LIHC cis rs11690935 0.959 rs7608403 chr2:172646765 A/C cg13550731 chr2:172543902 DYNC1I2 -0.94 -18.48 -0.71 2.22e-53 Schizophrenia; LIHC cis rs7249142 0.549 rs12975253 chr19:19279745 A/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -7.03 -0.36 1.11e-11 IgG glycosylation; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs7412746 0.658 rs4970982 chr1:150865084 G/C cg17724175 chr1:150552817 MCL1 0.41 8.17 0.4 6.08e-15 Melanoma; LIHC cis rs67460515 0.892 rs16832082 chr3:161043571 A/G cg03342759 chr3:160939853 NMD3 -0.62 -9.35 -0.45 1.21e-18 Parkinson's disease; LIHC cis rs35306767 0.714 rs28512382 chr10:1092195 G/C cg20503657 chr10:835505 NA 0.7 6.75 0.34 6.43e-11 Eosinophil percentage of granulocytes; LIHC cis rs9303401 0.659 rs34913878 chr17:56897094 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.19 0.55 1.22e-28 Cognitive test performance; LIHC cis rs16828019 0.852 rs12045171 chr1:41528805 G/A cg20697417 chr1:41786797 NA 0.3 5.9 0.3 8.86e-9 Intelligence (multi-trait analysis); LIHC cis rs17036023 1 rs17036023 chr1:117129711 C/T cg01558040 chr1:116184423 VANGL1 -0.59 -5.77 -0.3 1.76e-8 Asthma (childhood onset); LIHC cis rs875971 0.862 rs13536 chr7:66019190 G/A cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.34e-9 Aortic root size; LIHC cis rs4423214 0.840 rs1790343 chr11:71177207 T/C cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg05025164 chr4:1340916 KIAA1530 -0.65 -9.81 -0.47 3.6e-20 Obesity-related traits; LIHC cis rs2153535 0.580 rs6597318 chr6:8437289 G/A cg21535247 chr6:8435926 SLC35B3 0.58 7.87 0.39 4.84e-14 Motion sickness; LIHC cis rs651907 0.513 rs34963630 chr3:101504817 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.21 0.52 4.66e-25 Colorectal cancer; LIHC cis rs7520050 0.966 rs11579634 chr1:46466391 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 -0.41 -5.76 -0.3 1.85e-8 Red blood cell count;Reticulocyte count; LIHC cis rs74181299 0.927 rs2723064 chr2:65279805 T/C cg05010058 chr2:65284262 CEP68 0.4 6.78 0.34 5.3e-11 Pulse pressure; LIHC cis rs7914558 0.966 rs10883805 chr10:104708251 T/C cg15744005 chr10:104629667 AS3MT -0.4 -9.16 -0.44 4.98e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs9929218 0.954 rs9923925 chr16:68819444 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.67 -0.42 1.8e-16 Colorectal cancer; LIHC cis rs1904096 0.506 rs114312933 chr4:95216802 C/T cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.11 -0.44 7.04e-18 Type 2 diabetes; LIHC cis rs6967414 0.786 rs6948965 chr7:6758547 G/A cg00387323 chr7:6746715 ZNF12 0.67 7.47 0.37 6.56e-13 Hematocrit;Hemoglobin concentration; LIHC cis rs9549328 0.731 rs55804996 chr13:113625367 A/G cg08528486 chr13:113648767 MCF2L -0.41 -6.43 -0.33 4.22e-10 Systolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12857786 chr4:83934023 LIN54 0.42 6.13 0.31 2.47e-9 Pancreatic cancer; LIHC cis rs7903847 0.667 rs3818787 chr10:99145179 T/C cg06359132 chr10:99160096 RRP12 -0.39 -6.17 -0.32 1.89e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs11098699 0.784 rs6835971 chr4:124230999 A/G cg09941581 chr4:124220074 SPATA5 0.32 6.43 0.33 4.22e-10 Mosquito bite size; LIHC cis rs7712401 0.791 rs9327279 chr5:122122160 T/G cg18764291 chr5:122110994 SNX2 0.35 6.1 0.31 2.87e-9 Mean platelet volume; LIHC cis rs9733 0.596 rs17658705 chr1:150678071 A/C cg18016565 chr1:150552671 MCL1 -0.59 -11.47 -0.53 5.28e-26 Tonsillectomy; LIHC cis rs9918079 0.506 rs10214 chr4:15606431 T/C cg18470593 chr4:15471377 CC2D2A 0.39 5.82 0.3 1.35e-8 Obesity-related traits; LIHC cis rs7959452 0.532 rs2291005 chr12:69764388 A/G cg20891283 chr12:69753455 YEATS4 0.9 19.5 0.73 1.79e-57 Blood protein levels; LIHC cis rs35110281 0.686 rs162399 chr21:44950020 G/A cg04455712 chr21:45112962 RRP1B 0.47 7.61 0.38 2.63e-13 Mean corpuscular volume; LIHC cis rs568617 0.767 rs2231884 chr11:65656564 C/T cg04055107 chr11:65626734 MUS81;CFL1 0.46 6.13 0.31 2.41e-9 Crohn's disease; LIHC trans rs11165623 0.602 rs7517055 chr1:97007781 C/G cg10631902 chr5:14652156 NA -0.26 -6.51 -0.33 2.7e-10 Hip circumference;Waist circumference; LIHC cis rs3096299 0.748 rs3102339 chr16:89442711 C/T cg08392591 chr16:89556376 ANKRD11 0.39 5.84 0.3 1.23e-8 Multiple myeloma (IgH translocation); LIHC cis rs2629540 0.543 rs2559515 chr10:126513925 A/G cg08799069 chr10:126477246 METTL10 0.43 6.2 0.32 1.65e-9 Cocaine dependence; LIHC cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg19318889 chr4:1322082 MAEA -0.63 -10.17 -0.48 2.06e-21 Obesity-related traits; LIHC cis rs516243 0.703 rs169538 chr1:10737045 T/C cg02903756 chr1:10750680 CASZ1 -0.35 -6.34 -0.32 7.24e-10 Migraine - clinic-based; LIHC cis rs6840360 1.000 rs6845944 chr4:152604520 C/T cg22705602 chr4:152727874 NA -0.3 -6.12 -0.31 2.59e-9 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg06420487 chr17:61919686 SMARCD2 0.44 5.95 0.31 6.71e-9 Height; LIHC cis rs4268898 0.760 rs7597919 chr2:24563646 A/G cg06627628 chr2:24431161 ITSN2 0.45 6.39 0.33 5.49e-10 Asthma; LIHC cis rs9916302 0.904 rs9904334 chr17:37468336 G/A cg00129232 chr17:37814104 STARD3 0.39 6.25 0.32 1.23e-9 Glomerular filtration rate (creatinine); LIHC cis rs7100689 0.646 rs2050824 chr10:82123563 G/A cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg10210624 chr19:58662595 ZNF329 0.72 7.14 0.36 5.58e-12 Cholesterol, total; LIHC cis rs611744 0.967 rs677288 chr8:109177539 T/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs4660306 0.961 rs4660864 chr1:45966582 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC -0.69 -8.39 -0.41 1.31e-15 Homocysteine levels; LIHC cis rs10779751 1.000 rs742824 chr1:11274022 G/A cg08854313 chr1:11322531 MTOR 0.87 15.81 0.65 1.15e-42 Body mass index; LIHC cis rs722599 0.748 rs61978932 chr14:75342954 C/T cg08847533 chr14:75593920 NEK9 -0.54 -8.58 -0.42 3.41e-16 IgG glycosylation; LIHC cis rs17854409 0.881 rs12625401 chr20:61472939 A/T cg06598544 chr20:61472147 COL9A3 -0.91 -8.62 -0.42 2.49e-16 Obesity-related traits; LIHC cis rs796364 1.000 rs281763 chr2:200794870 C/T cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.61e-9 Schizophrenia; LIHC cis rs2991971 0.967 rs12133294 chr1:45988764 C/T cg24296786 chr1:45957014 TESK2 0.54 8.05 0.4 1.37e-14 High light scatter reticulocyte count; LIHC cis rs4665809 0.887 rs6546716 chr2:26263836 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.68 -0.42 1.68e-16 Gut microbiome composition (summer); LIHC cis rs1000083 0.748 rs3104166 chr5:96656684 A/T ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15065896 chr3:37285038 GOLGA4 0.52 7.38 0.37 1.21e-12 Pancreatic cancer; LIHC cis rs1555322 0.530 rs2250205 chr20:33867924 C/T cg17927777 chr20:33865990 NA 0.52 5.86 0.3 1.07e-8 Attention deficit hyperactivity disorder; LIHC cis rs17685 0.725 rs1044483 chr7:75659815 T/C cg04610667 chr7:75704037 NA 0.33 5.98 0.31 5.49e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg10755058 chr3:40428713 ENTPD3 0.39 6.67 0.34 1.03e-10 Renal cell carcinoma; LIHC cis rs3749237 0.595 rs4855861 chr3:49525962 G/T cg07636037 chr3:49044803 WDR6 0.56 8.46 0.42 7.75e-16 Resting heart rate; LIHC cis rs4332037 0.664 rs73046334 chr7:1887037 T/C cg23422044 chr7:1970798 MAD1L1 -0.54 -6.46 -0.33 3.5e-10 Bipolar disorder; LIHC cis rs9649213 0.593 rs13246942 chr7:97915021 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.98 -0.31 5.65e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs9911578 0.900 rs7214335 chr17:57158840 G/A cg05425664 chr17:57184151 TRIM37 -0.58 -8.67 -0.42 1.71e-16 Intelligence (multi-trait analysis); LIHC cis rs9733 0.596 rs12077833 chr1:150674333 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.1e-9 Tonsillectomy; LIHC cis rs17818399 0.597 rs12104572 chr2:46862466 C/G cg02822958 chr2:46747628 ATP6V1E2 0.37 5.98 0.31 5.5e-9 Height; LIHC cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg08645402 chr16:4508243 NA 0.4 7.59 0.38 3.06e-13 Schizophrenia; LIHC cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg03452623 chr4:187889614 NA 0.34 8.67 0.42 1.81e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs3762637 1.000 rs9858558 chr3:122139742 G/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC cis rs34779708 0.931 rs11596502 chr10:35387187 A/C cg04310649 chr10:35416472 CREM -0.44 -5.87 -0.3 1e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg07424592 chr7:64974309 NA 0.82 9.53 0.46 2.98e-19 Diabetic kidney disease; LIHC cis rs11098699 0.821 rs2047585 chr4:124231984 C/T cg09941581 chr4:124220074 SPATA5 -0.31 -6.29 -0.32 9.66e-10 Mosquito bite size; LIHC cis rs2290405 1.000 rs2290405 chr4:946974 A/G cg23939001 chr4:940644 TMEM175 -0.4 -7.29 -0.37 2.18e-12 Systemic sclerosis; LIHC cis rs7208859 0.623 rs8082537 chr17:29015932 T/C cg14067834 chr17:29058358 SUZ12P 0.62 6.44 0.33 4.12e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs637571 0.544 rs56239996 chr11:65730003 A/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.82 0.3 1.38e-8 Eosinophil percentage of white cells; LIHC cis rs4237845 0.537 rs11172367 chr12:58272486 T/G cg04478727 chr12:58166393 METTL1;FAM119B 0.6 8.35 0.41 1.71e-15 Intelligence (multi-trait analysis); LIHC cis rs6964587 0.839 rs2049314 chr7:91464134 C/T cg17063962 chr7:91808500 NA 0.96 17.49 0.69 2.23e-49 Breast cancer; LIHC cis rs963731 0.649 rs2924714 chr2:39333288 A/G cg04010122 chr2:39346883 SOS1 -0.68 -6.01 -0.31 4.7e-9 Corticobasal degeneration; LIHC trans rs2235573 0.527 rs139866 chr22:38354684 C/T cg19894588 chr14:64061835 NA 0.46 6.07 0.31 3.35e-9 Glioblastoma;Glioma; LIHC cis rs921968 0.607 rs529474 chr2:219463283 C/T cg17980119 chr2:219472607 PLCD4 0.34 5.86 0.3 1.06e-8 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.904 rs7924371 chr11:49620595 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -21.37 -0.76 5.99e-65 Height; LIHC cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg18305652 chr10:134549665 INPP5A 0.42 6.15 0.32 2.18e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs5753037 0.809 rs5752964 chr22:30208608 C/T cg01021169 chr22:30184971 ASCC2 -0.37 -6.92 -0.35 2.24e-11 Type 1 diabetes; LIHC cis rs903552 0.932 rs9806551 chr15:102008206 C/T cg06707286 chr15:102010195 PCSK6 -0.52 -7.61 -0.38 2.61e-13 Diabetic kidney disease; LIHC cis rs10193935 0.901 rs2286701 chr2:42555636 T/C cg27598129 chr2:42591480 NA -0.73 -11.03 -0.51 2.14e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs539514 0.690 rs480929 chr13:76312773 G/A cg04757411 chr13:76259545 LMO7 -0.47 -8.18 -0.4 5.52e-15 Type 1 diabetes; LIHC cis rs10463316 0.709 rs3857426 chr5:150789831 C/A cg03212797 chr5:150827313 SLC36A1 -0.45 -6.74 -0.34 6.66e-11 Metabolite levels (Pyroglutamine); LIHC cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg00149659 chr3:10157352 C3orf10 0.59 6.44 0.33 4.08e-10 Alzheimer's disease; LIHC cis rs7586673 0.866 rs7579662 chr2:161915810 G/A cg16506815 chr2:162101123 NA 0.46 7.46 0.37 6.99e-13 Intelligence (multi-trait analysis); LIHC cis rs9309473 1.000 rs9309473 chr2:73743982 A/G cg20560298 chr2:73613845 ALMS1 -0.57 -6.85 -0.35 3.48e-11 Metabolite levels; LIHC cis rs910316 1.000 rs175442 chr14:75603564 T/C cg08847533 chr14:75593920 NEK9 -0.87 -18.84 -0.71 8.05e-55 Height; LIHC cis rs2230307 0.536 rs534252 chr1:100472604 A/G cg24955406 chr1:100503596 HIAT1 0.62 6.2 0.32 1.62e-9 Carotid intima media thickness; LIHC cis rs12908161 1.000 rs4643294 chr15:85250253 C/T cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC cis rs11190604 0.767 rs10883477 chr10:102161396 A/G cg07080220 chr10:102295463 HIF1AN 0.45 6.29 0.32 9.6e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2236918 0.901 rs1635502 chr1:242039382 A/G cg17736920 chr1:242011382 EXO1 0.5 7.21 0.36 3.56e-12 Menopause (age at onset); LIHC cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.42 0.45 7.02e-19 Bipolar disorder; LIHC cis rs4819052 0.851 rs9977178 chr21:46664531 G/T cg22633049 chr21:46681294 NA -0.37 -6.29 -0.32 9.62e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4800452 0.956 rs4369779 chr18:20735408 T/C cg26136497 chr18:20735537 CABLES1 -0.44 -5.83 -0.3 1.26e-8 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs9916302 0.904 rs3744348 chr17:37417575 C/G cg03013999 chr17:37608204 MED1 0.36 6.05 0.31 3.9e-9 Glomerular filtration rate (creatinine); LIHC cis rs240764 0.817 rs240115 chr6:101053069 T/C cg09795085 chr6:101329169 ASCC3 0.52 7.33 0.37 1.66e-12 Neuroticism; LIHC cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg18876405 chr7:65276391 NA -0.54 -9.08 -0.44 8.74e-18 Aortic root size; LIHC trans rs459571 0.916 rs109536 chr9:136889987 G/C cg09836344 chr4:1243392 C4orf42;CTBP1 -0.62 -9.7 -0.46 8.11e-20 Platelet distribution width; LIHC cis rs6545883 0.929 rs2121660 chr2:61653058 T/C cg15711740 chr2:61764176 XPO1 0.41 5.72 0.3 2.35e-8 Tuberculosis; LIHC cis rs2732480 0.523 rs34286639 chr12:48629044 C/T cg21466736 chr12:48725269 NA -0.7 -10.65 -0.5 4.47e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs1144333 1.000 rs12078893 chr1:76370862 T/C cg22875332 chr1:76189707 ACADM 0.4 6.27 0.32 1.07e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg11890956 chr21:40555474 PSMG1 1.04 15.21 0.64 2.8e-40 Cognitive function; LIHC cis rs2625529 0.824 rs7183749 chr15:72377278 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.87 -0.3 1.02e-8 Red blood cell count; LIHC cis rs3741798 1.000 rs61922052 chr12:12497620 A/G cg08615371 chr12:12503544 MANSC1 0.91 7.34 0.37 1.54e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg08280861 chr8:58055591 NA 0.49 6.05 0.31 3.9e-9 Developmental language disorder (linguistic errors); LIHC trans rs8073060 0.586 rs225250 chr17:33941963 A/G cg19694781 chr19:47549865 TMEM160 -1.25 -13.43 -0.59 2.45e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs875971 0.862 rs908915 chr7:65614651 G/T cg18876405 chr7:65276391 NA -0.37 -6.6 -0.34 1.55e-10 Aortic root size; LIHC cis rs6089584 0.527 rs927589 chr20:60606363 A/G cg23262073 chr20:60523788 NA -0.29 -6.02 -0.31 4.47e-9 Body mass index; LIHC cis rs6141769 0.542 rs28548407 chr20:31301495 T/C cg13636640 chr20:31349939 DNMT3B -0.32 -5.74 -0.3 2.09e-8 Subjective well-being; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05119084 chr18:46477127 SMAD7 0.44 6.08 0.31 3.27e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs273218 1.000 rs273217 chr5:53380938 A/G ch.5.1024479R chr5:53302184 ARL15 0.64 10.13 0.48 2.8e-21 Migraine; LIHC cis rs2115630 0.641 rs11073613 chr15:85185893 G/A cg09876464 chr15:85330779 ZNF592 0.37 6.11 0.31 2.64e-9 P wave terminal force; LIHC trans rs1005277 0.505 rs200910 chr10:38108176 C/T cg23533926 chr12:111358616 MYL2 -0.33 -6.47 -0.33 3.33e-10 Extrinsic epigenetic age acceleration; LIHC cis rs10751667 0.666 rs7395321 chr11:940280 C/T cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.56e-13 Alzheimer's disease (late onset); LIHC cis rs9916302 0.851 rs11657899 chr17:37626963 G/A cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg00656387 chr3:40428638 ENTPD3 0.49 8.05 0.4 1.37e-14 Renal cell carcinoma; LIHC cis rs9921222 0.585 rs7195617 chr16:376781 A/G cg00101154 chr16:420108 MRPL28 0.46 7.24 0.36 2.97e-12 Bone mineral density (spine);Bone mineral density; LIHC cis rs11711311 1.000 rs9848993 chr3:113497914 T/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.17 0.44 4.42e-18 IgG glycosylation; LIHC cis rs17094222 0.504 rs4917904 chr10:102447292 G/A cg26540559 chr10:102447443 NA 0.39 7.66 0.38 1.98e-13 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1707322 1.000 rs785507 chr1:46541558 C/T cg03146154 chr1:46216737 IPP -0.45 -7.07 -0.36 8.62e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs5997397 0.934 rs6005864 chr22:29157487 A/G cg02153584 chr22:29168773 CCDC117 -0.52 -7.82 -0.39 6.43e-14 Red cell distribution width; LIHC cis rs11583043 1.000 rs34915449 chr1:101476786 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.58 7.77 0.39 9.01e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs877282 1.000 rs112522746 chr10:772288 T/C cg22713356 chr15:30763199 NA 1.23 10.89 0.51 6.83e-24 Uric acid levels; LIHC cis rs739401 0.572 rs7111857 chr11:3068106 A/G cg20651018 chr11:3035856 CARS 0.36 5.86 0.3 1.06e-8 Longevity; LIHC cis rs13108904 0.557 rs1250097 chr4:1238338 C/T cg19318889 chr4:1322082 MAEA -0.62 -9.98 -0.47 9.33e-21 Obesity-related traits; LIHC trans rs75804782 0.641 rs6715311 chr2:239363321 A/G cg01134436 chr17:81009848 B3GNTL1 0.73 6.36 0.33 6.57e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs4819052 0.851 rs914214 chr21:46697820 G/T cg22633049 chr21:46681294 NA -0.38 -6.32 -0.32 8.16e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.49 0.42 6.5e-16 Platelet count; LIHC cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg02244288 chr16:89573955 SPG7 -0.3 -5.73 -0.3 2.2e-8 Multiple myeloma (IgH translocation); LIHC trans rs9747201 1.000 rs12451470 chr17:80177532 G/A cg07393940 chr7:158741817 NA 0.54 6.25 0.32 1.21e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4332037 0.762 rs11770612 chr7:1915493 A/C cg23422044 chr7:1970798 MAD1L1 -0.69 -10.63 -0.5 5.58e-23 Bipolar disorder; LIHC cis rs7309 0.935 rs6432674 chr2:162025322 G/T cg16506815 chr2:162101123 NA 0.57 9.86 0.47 2.46e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg16606324 chr3:10149918 C3orf24 0.56 6.08 0.31 3.24e-9 Alzheimer's disease; LIHC cis rs1697139 1.000 rs1705397 chr5:66511062 G/T cg16691251 chr5:66510806 NA -0.47 -6.81 -0.35 4.38e-11 Breast cancer; LIHC cis rs4700695 0.614 rs437399 chr5:65208533 A/G cg21114390 chr5:65439923 SFRS12 0.46 5.83 0.3 1.3e-8 Facial morphology (factor 19); LIHC trans rs9951602 0.512 rs12607938 chr18:76651887 A/C cg02800362 chr5:177631904 HNRNPAB 0.66 10.76 0.5 1.87e-23 Obesity-related traits; LIHC cis rs9640161 0.659 rs7781827 chr7:150008858 T/C cg27494647 chr7:150038898 RARRES2 0.3 5.85 0.3 1.16e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs4803468 1.000 rs284648 chr19:41926790 T/C cg14132834 chr19:41945861 ATP5SL -0.46 -6.78 -0.34 5.38e-11 Height; LIHC trans rs1814175 0.817 rs7481230 chr11:49772235 G/A cg03929089 chr4:120376271 NA -0.9 -18.25 -0.7 1.98e-52 Height; LIHC cis rs6762477 0.748 rs34877766 chr3:50234126 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.53 8.17 0.4 6.14e-15 Menarche (age at onset); LIHC cis rs116095464 0.558 rs6555056 chr5:226222 T/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs4332037 0.713 rs56093134 chr7:1973970 C/T cg23422044 chr7:1970798 MAD1L1 -0.59 -6.51 -0.33 2.68e-10 Bipolar disorder; LIHC cis rs694739 0.796 rs479777 chr11:64107477 A/G cg23796481 chr11:64053134 BAD;GPR137 0.59 8.6 0.42 2.91e-16 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg14828511 chr1:107599125 PRMT6 0.41 5.79 0.3 1.58e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs589448 0.934 rs554591 chr12:69753847 T/C cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 1.02e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs769267 0.929 rs2965180 chr19:19491973 T/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.53 -8.13 -0.4 8.08e-15 Tonsillectomy; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg11143796 chr4:178363279 AGA -0.43 -6.21 -0.32 1.58e-9 Alopecia areata; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20273774 chr5:180671298 GNB2L1;SNORD95 0.5 6.74 0.34 6.56e-11 Pancreatic cancer; LIHC cis rs508618 0.731 rs576462 chr1:231544607 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.64 -9.29 -0.45 1.85e-18 Red blood cell count; LIHC cis rs5769765 0.632 rs13056783 chr22:50259152 A/T cg26441486 chr22:50317300 CRELD2 -0.34 -5.98 -0.31 5.62e-9 Schizophrenia; LIHC cis rs986417 0.551 rs4901991 chr14:61065025 T/C cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs79387448 0.745 rs72993722 chr2:103124916 A/G cg09003973 chr2:102972529 NA 0.82 7.15 0.36 5.19e-12 Gut microbiota (bacterial taxa); LIHC cis rs6963495 0.818 rs55794529 chr7:105165747 T/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs7714584 1.000 rs3906528 chr5:150266718 G/A cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs7238033 0.663 rs11877720 chr18:43318255 A/G cg20610511 chr18:43302872 SLC14A1 0.39 6.48 0.33 3.26e-10 Bladder cancer; LIHC cis rs7208859 0.673 rs9909497 chr17:29173228 C/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17826219 0.636 rs79565452 chr17:29142841 T/C cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Body mass index; LIHC cis rs10464366 0.544 rs9639812 chr7:39192058 C/T cg18850127 chr7:39170497 POU6F2 0.45 7.91 0.39 3.66e-14 IgG glycosylation; LIHC cis rs6582630 0.519 rs1851121 chr12:38389467 T/C cg26384229 chr12:38710491 ALG10B 0.59 8.22 0.41 4.37e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs4650994 0.550 rs10913573 chr1:178530455 G/A cg05350800 chr1:178550844 NA -0.34 -7.35 -0.37 1.48e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7572733 0.534 rs11890137 chr2:198816662 G/A cg10820045 chr2:198174542 NA 0.48 7.19 0.36 4.17e-12 Dermatomyositis; LIHC cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg11301795 chr4:187892539 NA -0.26 -7.04 -0.36 1.04e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14217534 chr12:49525474 TUBA1B 0.45 6.29 0.32 9.7e-10 Pancreatic cancer; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC trans rs2018683 1.000 rs4719962 chr7:28999237 G/A cg19402173 chr7:128379420 CALU -0.43 -6.86 -0.35 3.25e-11 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs9581857 0.579 rs3759434 chr13:27997700 A/C cg22138327 chr13:27999177 GTF3A 0.54 7.91 0.39 3.53e-14 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs694739 0.654 rs10897488 chr11:64140806 T/C cg23796481 chr11:64053134 BAD;GPR137 0.46 6.15 0.32 2.11e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs3740540 0.530 rs2362503 chr10:126290538 T/C cg04949429 chr10:126290192 LHPP 0.45 7.34 0.37 1.55e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs763121 0.819 rs5757133 chr22:38947835 A/G cg14440974 chr22:39074834 NA 0.44 6.98 0.35 1.51e-11 Menopause (age at onset); LIHC cis rs4665809 1.000 rs4233709 chr2:26291493 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.65 7.92 0.39 3.26e-14 Gut microbiome composition (summer); LIHC cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg08687515 chr19:58661962 ZNF329 0.99 7.72 0.39 1.32e-13 Cholesterol, total; LIHC cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg12310025 chr6:25882481 NA 0.48 6.06 0.31 3.59e-9 Intelligence (multi-trait analysis); LIHC cis rs8077889 0.917 rs1859048 chr17:41892039 A/C cg26893861 chr17:41843967 DUSP3 -0.85 -9.7 -0.46 8.45e-20 Triglycerides; LIHC cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -11.04 -0.51 1.96e-24 Platelet count; LIHC cis rs10464366 0.746 rs6945547 chr7:39145389 C/G cg18850127 chr7:39170497 POU6F2 0.44 8.03 0.4 1.6e-14 IgG glycosylation; LIHC cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg03806693 chr22:41940476 POLR3H -1.05 -12.26 -0.55 6.98e-29 Vitiligo; LIHC cis rs6695567 1.000 rs6588467 chr1:53630304 G/A cg20326410 chr1:53600821 SLC1A7 0.3 6.31 0.32 8.6e-10 Systemic lupus erythematosus; LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg24503407 chr1:205819492 PM20D1 -0.72 -10.32 -0.49 6.42e-22 Menarche (age at onset); LIHC cis rs1005277 0.540 rs2224248 chr10:38451886 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7572733 0.534 rs700667 chr2:198677508 T/C cg00792783 chr2:198669748 PLCL1 0.46 6.84 0.35 3.67e-11 Dermatomyositis; LIHC cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.25e-12 Bipolar disorder; LIHC trans rs12935229 0.756 rs11149981 chr16:77370138 G/T cg11525352 chr7:43351604 HECW1 0.31 6.12 0.31 2.51e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs); LIHC cis rs2404602 0.647 rs12904417 chr15:76964152 A/G cg03037974 chr15:76606532 NA 0.61 10.3 0.49 7.73e-22 Blood metabolite levels; LIHC cis rs6754311 0.731 rs7569057 chr2:136583958 A/C cg15123519 chr2:136567270 LCT -0.45 -9.16 -0.44 4.74e-18 Mosquito bite size; LIHC cis rs12497850 1.000 rs1352420 chr3:48757291 A/G cg07636037 chr3:49044803 WDR6 0.88 15.16 0.63 4.7e-40 Parkinson's disease; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg07342512 chr1:65886002 LEPROT;LEPR -0.46 -6.45 -0.33 3.84e-10 Eotaxin levels; LIHC cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg00149659 chr3:10157352 C3orf10 0.55 5.9 0.3 8.56e-9 Alzheimer's disease; LIHC cis rs854765 0.647 rs6502637 chr17:17986098 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.33 6.15 0.32 2.12e-9 Total body bone mineral density; LIHC cis rs35306767 0.855 rs56222464 chr10:867535 C/G cg26597838 chr10:835615 NA 1.5 16.55 0.67 1.29e-45 Eosinophil percentage of granulocytes; LIHC cis rs55665837 0.540 rs1007392 chr11:14774591 A/G cg25251204 chr11:14927456 NA 0.41 5.85 0.3 1.12e-8 Vitamin D levels; LIHC cis rs72781680 1.000 rs72781671 chr2:24231123 A/G cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs2599510 0.807 rs176416 chr2:32652223 A/G cg02381751 chr2:32503542 YIPF4 -0.49 -6.61 -0.34 1.48e-10 Interleukin-18 levels; LIHC cis rs16858210 0.874 rs7618182 chr3:183607003 T/A cg25686905 chr3:183603175 PARL -0.49 -9.24 -0.45 2.73e-18 Menopause (age at onset); LIHC cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg03806693 chr22:41940476 POLR3H -1.02 -12.27 -0.55 6.15e-29 Vitiligo; LIHC cis rs6570726 0.967 rs6903252 chr6:145922777 A/G cg23711669 chr6:146136114 FBXO30 0.58 9.94 0.47 1.33e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs1568889 0.877 rs17310076 chr11:28147590 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.47 5.96 0.31 6.22e-9 Bipolar disorder; LIHC cis rs1577917 1.000 rs35385043 chr6:86648546 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.71 -0.38 1.36e-13 Response to antipsychotic treatment; LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg14393609 chr7:65229607 NA -0.41 -6.87 -0.35 3e-11 Calcium levels; LIHC cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7098414 0.511 rs10887826 chr10:82151380 C/T cg01528321 chr10:82214614 TSPAN14 0.41 6.32 0.32 8.35e-10 Post bronchodilator FEV1; LIHC cis rs992157 1.000 rs13429408 chr2:219142860 C/A cg20019365 chr2:219134978 PNKD;AAMP 0.8 12.99 0.57 1.23e-31 Colorectal cancer; LIHC cis rs60871478 1.000 rs60871478 chr7:827325 A/G cg27478167 chr7:817139 HEATR2 -0.42 -5.97 -0.31 5.86e-9 Cerebrospinal P-tau181p levels; LIHC cis rs10847980 0.590 rs58182048 chr12:123287708 C/T cg07706471 chr12:123319906 HIP1R 0.75 8.16 0.4 6.55e-15 Adiponectin levels; LIHC trans rs11039798 0.544 rs114343057 chr11:48558172 C/T cg15704280 chr7:45808275 SEPT13 0.57 6.34 0.32 7.3e-10 Axial length; LIHC cis rs7523273 0.565 rs1359147 chr1:207886150 C/T cg22525895 chr1:207977042 MIR29B2 0.52 7.69 0.38 1.58e-13 Schizophrenia; LIHC cis rs2404602 0.583 rs12907668 chr15:76589767 A/T cg23625390 chr15:77176239 SCAPER 0.34 5.88 0.3 9.59e-9 Blood metabolite levels; LIHC cis rs11229555 0.609 rs4598685 chr11:58216864 A/G cg15696309 chr11:58395628 NA -0.64 -7.45 -0.37 7.92e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1008375 1.000 rs6818639 chr4:17633049 A/G cg15017067 chr4:17643749 FAM184B 0.34 5.84 0.3 1.23e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs62380364 0.542 rs2457979 chr5:88039660 T/A cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis); LIHC cis rs9394841 0.692 rs9381094 chr6:41800629 T/C cg17623882 chr6:41773611 USP49 -0.43 -5.85 -0.3 1.13e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs875971 0.862 rs6460307 chr7:66060871 A/G cg18876405 chr7:65276391 NA 0.33 6.29 0.32 9.82e-10 Aortic root size; LIHC cis rs7833790 0.654 rs7835342 chr8:82698092 A/G cg02079420 chr8:82753780 SNX16 0.34 6.06 0.31 3.6e-9 Diastolic blood pressure; LIHC cis rs35306767 0.903 rs11253493 chr10:936931 T/C cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs67311347 0.911 rs6773917 chr3:40469254 G/T cg18306943 chr3:40428807 ENTPD3 0.33 5.87 0.3 1.04e-8 Renal cell carcinoma; LIHC cis rs7131987 0.650 rs11050188 chr12:29473108 A/C cg00204748 chr12:29376779 FAR2 0.4 7.41 0.37 1.03e-12 QT interval; LIHC cis rs10411936 0.720 rs7252649 chr19:16582785 G/T cg10248733 chr19:16607483 C19orf44;CALR3 0.48 6.41 0.33 4.7e-10 White blood cell count;Multiple sclerosis; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg05484376 chr2:27715224 FNDC4 0.38 6.46 0.33 3.59e-10 Total body bone mineral density; LIHC cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg25894440 chr7:65020034 NA 0.52 5.88 0.3 9.54e-9 Diabetic kidney disease; LIHC cis rs11864453 0.647 rs9932062 chr16:72136055 T/C cg16558253 chr16:72132732 DHX38 -0.41 -6.6 -0.34 1.61e-10 Fibrinogen levels; LIHC cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg09904177 chr6:26538194 HMGN4 0.55 10.59 0.5 7.63e-23 Intelligence (multi-trait analysis); LIHC cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg13393036 chr8:95962371 TP53INP1 -0.43 -10.11 -0.48 3.42e-21 Type 2 diabetes; LIHC cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg24531977 chr5:56204891 C5orf35 -0.68 -9.78 -0.47 4.57e-20 Initial pursuit acceleration; LIHC cis rs921968 0.678 rs500422 chr2:219432995 C/A cg18887096 chr2:219472410 PLCD4 0.35 5.97 0.31 6.11e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs2742417 0.603 rs1468542 chr3:45779136 A/T cg04837898 chr3:45731254 SACM1L 0.53 9.06 0.44 1.05e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs6752107 0.935 rs1596017 chr2:234147930 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.47 7.0 0.35 1.33e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs782590 0.935 rs2627776 chr2:55873301 T/A cg03859395 chr2:55845619 SMEK2 0.91 16.07 0.66 1.1e-43 Metabolic syndrome; LIHC cis rs2404602 0.646 rs3764245 chr15:77223176 G/C cg03037974 chr15:76606532 NA 0.61 10.74 0.5 2.21e-23 Blood metabolite levels; LIHC cis rs853679 0.517 rs9357066 chr6:28129831 T/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs1005277 0.579 rs1780136 chr10:38501453 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12540874 0.542 rs4947581 chr7:50565967 G/A cg14593290 chr7:50529359 DDC -0.35 -6.14 -0.31 2.35e-9 Systemic sclerosis; LIHC cis rs67460515 0.563 rs6441362 chr3:160877613 G/A cg03342759 chr3:160939853 NMD3 -0.64 -9.6 -0.46 1.79e-19 Parkinson's disease; LIHC cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg13393036 chr8:95962371 TP53INP1 -0.36 -8.41 -0.41 1.14e-15 Type 2 diabetes; LIHC cis rs11702148 0.552 rs2834235 chr21:34901423 C/T cg14850771 chr21:34775459 IFNGR2 -0.44 -7.08 -0.36 8.04e-12 Mean corpuscular hemoglobin; LIHC cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg06238570 chr21:40685208 BRWD1 -0.58 -9.65 -0.46 1.24e-19 Cognitive function; LIHC cis rs6785206 0.892 rs6439143 chr3:128425132 C/T cg16766828 chr3:128327626 NA -0.59 -6.59 -0.34 1.63e-10 Lymphocyte percentage of white cells; LIHC cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg03452623 chr4:187889614 NA -0.32 -8.24 -0.41 3.65e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs6762477 0.748 rs34877766 chr3:50234126 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.6 9.38 0.45 9.65e-19 Menarche (age at onset); LIHC cis rs1003719 1.000 rs2835608 chr21:38493455 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.75 11.45 0.53 6.52e-26 Eye color traits; LIHC cis rs9560113 0.960 rs953260 chr13:112173685 C/T cg14154082 chr13:112174009 NA 0.29 6.1 0.31 2.81e-9 Menarche (age at onset); LIHC cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg20607798 chr8:58055168 NA 0.6 7.25 0.36 2.86e-12 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.715 rs17293580 chr10:1034895 T/C cg26597838 chr10:835615 NA 0.84 7.73 0.39 1.25e-13 Eosinophil percentage of granulocytes; LIHC cis rs1664789 1.000 rs787544 chr5:53273342 G/T ch.5.1024479R chr5:53302184 ARL15 0.49 7.92 0.39 3.26e-14 Waist circumference adjusted for body mass index; LIHC cis rs2153535 0.542 rs915354 chr6:8440357 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.66 0.42 1.91e-16 Motion sickness; LIHC cis rs77637988 0.604 rs17855177 chr2:48602252 C/T cg15846641 chr2:48541264 FOXN2 0.57 7.63 0.38 2.36e-13 Joint mobility (Beighton score); LIHC cis rs4819052 0.851 rs2236446 chr21:46678985 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.98 0.51 3.15e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs61990749 0.597 rs12887282 chr14:78200585 C/A cg23188588 chr14:78226832 SNW1;C14orf178 0.63 10.5 0.49 1.59e-22 Fibroblast growth factor basic levels; LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg22903471 chr2:27725779 GCKR -0.5 -8.59 -0.42 3.14e-16 Total body bone mineral density; LIHC cis rs3741404 1.000 rs11603042 chr11:64003843 G/T cg18225595 chr11:63971243 STIP1 0.63 9.41 0.45 7.61e-19 Platelet count; LIHC cis rs2637030 0.515 rs2130744 chr5:52896723 C/T cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.24e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs9818758 0.607 rs9850917 chr3:49286983 A/G cg00383909 chr3:49044727 WDR6 0.8 6.81 0.35 4.29e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs56091001 0.528 rs9616387 chr22:50313219 G/A cg09182678 chr22:50328711 NA -0.7 -7.38 -0.37 1.19e-12 Acne (severe); LIHC cis rs748404 0.560 rs529611 chr15:43805988 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.34 0.37 1.57e-12 Lung cancer; LIHC cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg05025164 chr4:1340916 KIAA1530 0.39 5.98 0.31 5.73e-9 Obesity-related traits; LIHC trans rs597503 1.000 rs530612 chr18:6942997 A/G cg12380209 chr10:120515094 C10orf46 0.6 6.17 0.32 1.97e-9 Sudden cardiac arrest; LIHC cis rs943466 1.000 rs12524835 chr6:33730843 G/C cg25922239 chr6:33757077 LEMD2 -0.5 -5.89 -0.3 9.34e-9 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs4665809 1.000 rs4665304 chr2:26313406 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.87 -0.43 4.13e-17 Gut microbiome composition (summer); LIHC trans rs1814175 0.647 rs4881649 chr11:49845560 A/G cg03929089 chr4:120376271 NA -0.59 -9.85 -0.47 2.48e-20 Height; LIHC cis rs763121 0.962 rs6001159 chr22:38966487 A/G cg14440974 chr22:39074834 NA -0.34 -5.78 -0.3 1.71e-8 Menopause (age at onset); LIHC cis rs763121 0.853 rs9306329 chr22:39072454 C/T cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg04546413 chr19:29218101 NA 0.56 9.98 0.47 9.72e-21 Methadone dose in opioid dependence; LIHC cis rs3768617 0.510 rs10797837 chr1:183075121 C/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.93 0.51 4.56e-24 Fuchs's corneal dystrophy; LIHC cis rs2153535 0.580 rs6597330 chr6:8492076 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg06481639 chr22:41940642 POLR3H -0.7 -6.97 -0.35 1.68e-11 Vitiligo; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15055890 chr3:11747650 VGLL4 -0.33 -7.09 -0.36 7.64e-12 Calcium levels; LIHC cis rs7264396 0.887 rs224419 chr20:34143092 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.36 -6.35 -0.32 6.8e-10 Total cholesterol levels; LIHC cis rs10508774 1.000 rs12415699 chr10:32749404 A/C cg01819863 chr10:32635814 EPC1 0.65 6.09 0.31 3.05e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6500602 0.964 rs2304633 chr16:4496973 T/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.42 5.84 0.3 1.19e-8 Schizophrenia; LIHC cis rs2228479 0.850 rs11646766 chr16:89838578 A/T cg14709524 chr16:89940631 TCF25 0.49 6.0 0.31 5.09e-9 Skin colour saturation; LIHC cis rs12479064 0.724 rs11885942 chr2:100004165 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.64 -7.89 -0.39 4.04e-14 Chronic sinus infection; LIHC cis rs9649213 0.593 rs1468340 chr7:97987676 T/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs1983891 1.000 rs2104506 chr6:41533579 C/A cg20194872 chr6:41519635 FOXP4 0.44 6.89 0.35 2.67e-11 Prostate cancer; LIHC cis rs66573146 0.831 rs66645969 chr4:6985614 G/A cg15105060 chr4:7024189 TBC1D14 -0.74 -6.56 -0.33 2.04e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs4862307 0.623 rs11730046 chr4:184988245 C/G cg22054328 chr4:184930219 STOX2 0.36 5.84 0.3 1.2e-8 Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg21724239 chr8:58056113 NA 0.63 7.52 0.38 4.92e-13 Developmental language disorder (linguistic errors); LIHC cis rs4803468 1.000 rs284652 chr19:41928652 C/T cg09537434 chr19:41945824 ATP5SL -1.03 -21.47 -0.76 2.4e-65 Height; LIHC cis rs6430585 0.528 rs309133 chr2:136751842 A/C cg07169764 chr2:136633963 MCM6 0.98 14.81 0.63 1.08e-38 Corneal structure; LIHC cis rs9911578 0.817 rs304264 chr17:56749628 A/G cg12560992 chr17:57184187 TRIM37 0.95 17.38 0.68 6.34e-49 Intelligence (multi-trait analysis); LIHC cis rs798554 0.757 rs2533882 chr7:2846894 G/T cg13628971 chr7:2884303 GNA12 0.54 7.77 0.39 9.01e-14 Height; LIHC cis rs6748734 0.948 rs9973366 chr2:241838151 T/C cg04034577 chr2:241836375 C2orf54 -0.48 -11.27 -0.52 2.8e-25 Urinary metabolites; LIHC trans rs75804782 0.521 rs72993034 chr2:239385895 C/T cg01134436 chr17:81009848 B3GNTL1 0.86 7.2 0.36 3.82e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs28595532 0.748 rs72670246 chr4:119335061 G/A cg21605333 chr4:119757512 SEC24D 0.96 7.4 0.37 1.04e-12 Cannabis dependence symptom count; LIHC cis rs10865541 0.934 rs4627605 chr2:3411923 G/A cg11642891 chr2:3452563 TTC15 -0.42 -6.73 -0.34 6.99e-11 Obesity-related traits; LIHC cis rs912057 1.000 rs1294410 chr6:6738752 C/T cg06612196 chr6:6737390 NA -0.5 -9.41 -0.45 7.37e-19 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs2302190 0.882 rs12942018 chr17:56613277 C/T cg12560992 chr17:57184187 TRIM37 0.69 8.88 0.43 3.9e-17 Vitamin D levels; LIHC cis rs763121 0.962 rs138703 chr22:39132748 C/T cg14440974 chr22:39074834 NA -0.34 -5.81 -0.3 1.43e-8 Menopause (age at onset); LIHC cis rs992157 0.798 rs10932772 chr2:219177148 C/T cg00012203 chr2:219082015 ARPC2 0.84 13.36 0.59 4.6e-33 Colorectal cancer; LIHC cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs16854884 0.586 rs6440212 chr3:143748526 T/C cg06585982 chr3:143692056 C3orf58 0.58 7.55 0.38 4.11e-13 Economic and political preferences (feminism/equality); LIHC cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg17971929 chr21:40555470 PSMG1 -0.67 -7.8 -0.39 7.53e-14 Cognitive function; LIHC cis rs1005277 0.579 rs2505248 chr10:38459097 A/G cg00409905 chr10:38381863 ZNF37A -0.6 -10.6 -0.5 6.66e-23 Extrinsic epigenetic age acceleration; LIHC cis rs3008870 1.000 rs4620509 chr1:67449941 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs709400 0.663 rs8015918 chr14:103942991 A/G cg26031613 chr14:104095156 KLC1 0.71 9.19 0.45 3.84e-18 Body mass index; LIHC cis rs2228479 0.702 rs11649501 chr16:89850957 A/T cg06558623 chr16:89946397 TCF25 0.84 11.03 0.51 2.02e-24 Skin colour saturation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21215811 chr17:40925428 VPS25 0.48 6.84 0.35 3.72e-11 Lung function (FEV1/FVC); LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs1957429 0.901 rs1957432 chr14:65352796 A/G cg23373153 chr14:65346875 NA 0.8 11.23 0.52 3.98e-25 Pediatric areal bone mineral density (radius); LIHC cis rs10876993 0.928 rs7136269 chr12:58075937 G/A cg18357645 chr12:58087776 OS9 0.52 8.53 0.42 4.91e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs12477438 0.520 rs11678456 chr2:99708237 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 13.3 0.58 7.74e-33 Chronic sinus infection; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg09331995 chr7:27309021 NA 0.56 6.47 0.33 3.35e-10 Mean platelet volume; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27380774 chr11:1000560 AP2A2 0.44 6.64 0.34 1.21e-10 Longevity; LIHC cis rs9640161 0.711 rs55881542 chr7:150025734 G/A cg17279839 chr7:150038598 RARRES2 0.58 11.56 0.53 2.56e-26 Blood protein levels;Circulating chemerin levels; LIHC cis rs7903847 0.642 rs10882911 chr10:99138064 A/C cg06359132 chr10:99160096 RRP12 -0.41 -6.23 -0.32 1.35e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs12579753 0.956 rs11115039 chr12:82217338 A/C cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.48e-9 Resting heart rate; LIHC cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg00684032 chr4:1343700 KIAA1530 0.51 7.19 0.36 4.08e-12 Obesity-related traits; LIHC cis rs599083 0.573 rs3018713 chr11:68390986 A/G cg01657329 chr11:68192670 LRP5 -0.51 -7.48 -0.37 6.52e-13 Bone mineral density (spine); LIHC cis rs523522 0.962 rs1050187 chr12:120902111 A/G cg12219531 chr12:120966889 COQ5 -0.64 -12.5 -0.56 8.88e-30 High light scatter reticulocyte count; LIHC cis rs4268898 0.529 rs4426488 chr2:24372815 A/G cg06627628 chr2:24431161 ITSN2 0.47 6.9 0.35 2.46e-11 Asthma; LIHC cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg24642844 chr7:1081250 C7orf50 -0.95 -9.26 -0.45 2.25e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10751667 0.600 rs10902264 chr11:1003523 G/A cg06064525 chr11:970664 AP2A2 -0.44 -10.62 -0.5 5.79e-23 Alzheimer's disease (late onset); LIHC cis rs34779708 0.966 rs12775759 chr10:35400183 G/T cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7587476 0.861 rs17488049 chr2:215651750 G/A cg04004882 chr2:215674386 BARD1 0.52 6.32 0.32 8.02e-10 Neuroblastoma; LIHC cis rs3820068 0.705 rs4646109 chr1:15817319 T/C cg17385448 chr1:15911702 AGMAT 0.38 6.39 0.33 5.34e-10 Systolic blood pressure; LIHC cis rs3820500 0.543 rs2211130 chr1:118014894 C/T cg20383390 chr1:117909022 MAN1A2 0.46 5.91 0.3 8.43e-9 Pneumonia; LIHC cis rs11758351 1.000 rs2143346 chr6:26198449 C/G cg06951627 chr6:26196580 NA -0.52 -5.98 -0.31 5.48e-9 Gout;Renal underexcretion gout; LIHC trans rs1814175 0.676 rs11040647 chr11:49935947 A/C cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg21448741 chr8:58168803 NA 0.35 6.51 0.33 2.73e-10 Developmental language disorder (linguistic errors); LIHC cis rs3796352 0.667 rs9831977 chr3:52854140 T/G cg04865290 chr3:52927548 TMEM110 -0.43 -5.76 -0.3 1.93e-8 Immune reponse to smallpox (secreted IL-2); LIHC cis rs523522 0.923 rs10774553 chr12:120954984 T/C cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs6565180 0.926 rs4788413 chr16:30410445 C/T cg17640201 chr16:30407289 ZNF48 0.78 12.61 0.56 3.38e-30 Tonsillectomy; LIHC cis rs1348850 0.561 rs57986285 chr2:178468663 C/T cg27490568 chr2:178487706 NA 1.1 11.84 0.54 2.52e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs11039798 0.688 rs10839007 chr11:48703442 A/C cg15704280 chr7:45808275 SEPT13 0.62 6.49 0.33 2.96e-10 Axial length; LIHC cis rs9611565 0.559 rs13056262 chr22:42081921 A/G cg03806693 chr22:41940476 POLR3H 0.98 10.61 0.5 6.31e-23 Vitiligo; LIHC cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg24675658 chr1:53192096 ZYG11B -0.58 -8.91 -0.43 3.16e-17 Monocyte count; LIHC cis rs2832191 0.791 rs4817270 chr21:30480368 G/A cg08807101 chr21:30365312 RNF160 -0.63 -10.01 -0.48 7.61e-21 Dental caries; LIHC trans rs208520 0.526 rs1385219 chr6:66754476 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.86 15.53 0.64 1.49e-41 Exhaled nitric oxide output; LIHC cis rs941408 0.928 rs2260414 chr19:2796316 G/A cg06609049 chr19:2785107 THOP1 0.55 9.68 0.46 9.7e-20 Total cholesterol levels; LIHC cis rs6424115 0.793 rs2502998 chr1:24198327 T/A cg10978503 chr1:24200527 CNR2 0.34 8.25 0.41 3.46e-15 Immature fraction of reticulocytes; LIHC cis rs9341808 0.754 rs6907729 chr6:81004922 A/T cg08355045 chr6:80787529 NA -0.31 -6.42 -0.33 4.63e-10 Sitting height ratio; LIHC cis rs10883723 1.000 rs10883723 chr10:104225832 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 11.47 0.53 5.44e-26 Allergic disease (asthma, hay fever or eczema); LIHC trans rs1005277 0.579 rs1780146 chr10:38517874 C/A cg23533926 chr12:111358616 MYL2 -0.33 -6.26 -0.32 1.12e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2180341 0.843 rs4895821 chr6:127572761 T/A cg24812749 chr6:127587940 RNF146 0.97 15.07 0.63 1.01e-39 Breast cancer; LIHC cis rs11122272 0.735 rs2808585 chr1:231514218 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.31 0.45 1.6e-18 Hemoglobin concentration; LIHC cis rs708547 0.581 rs10020462 chr4:57825593 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.51 -7.62 -0.38 2.45e-13 Response to bleomycin (chromatid breaks); LIHC cis rs2204008 0.805 rs4882575 chr12:37940573 G/A cg26384229 chr12:38710491 ALG10B -0.5 -7.05 -0.36 1.02e-11 Bladder cancer; LIHC cis rs2153535 0.521 rs6939827 chr6:8461360 C/G cg21535247 chr6:8435926 SLC35B3 0.63 8.24 0.41 3.84e-15 Motion sickness; LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.56 -7.93 -0.39 3.21e-14 Lymphocyte counts; LIHC cis rs2625529 0.824 rs7170461 chr15:72218599 C/A cg16672083 chr15:72433130 SENP8 -0.31 -5.79 -0.3 1.63e-8 Red blood cell count; LIHC trans rs1432089 0.773 rs6845629 chr4:171784030 C/G cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs7618501 1.000 rs2234391 chr3:49842625 A/G cg24110177 chr3:50126178 RBM5 -0.46 -7.23 -0.36 3.19e-12 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg18357526 chr6:26021779 HIST1H4A 0.9 12.0 0.54 6.54e-28 Intelligence (multi-trait analysis); LIHC cis rs896854 0.654 rs896846 chr8:95972453 G/A cg13393036 chr8:95962371 TP53INP1 -0.37 -8.55 -0.42 4.1e-16 Type 2 diabetes; LIHC cis rs55665837 0.961 rs12795972 chr11:14443775 C/T cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC trans rs1814175 0.817 rs10769641 chr11:49960141 A/G cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC trans rs1814175 0.587 rs7937757 chr11:49978342 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC trans rs1814175 0.645 rs6486022 chr11:49776137 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.97 0.35 1.66e-11 Height; LIHC cis rs4819052 0.851 rs2838844 chr21:46670733 A/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.55 0.38 3.88e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1577917 1.000 rs1857965 chr6:86630776 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC cis rs9377188 0.707 rs2500540 chr6:149330806 A/T cg03945663 chr6:149309952 UST -0.27 -6.36 -0.33 6.59e-10 Cancer; LIHC cis rs2576037 0.583 rs578451 chr18:44404525 T/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.81 -0.3 1.4e-8 Personality dimensions; LIHC cis rs5769765 1.000 rs2295408 chr22:50261051 A/G cg26441486 chr22:50317300 CRELD2 -0.34 -6.05 -0.31 3.79e-9 Schizophrenia; LIHC cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg25894440 chr7:65020034 NA -0.55 -6.33 -0.32 7.79e-10 Diabetic kidney disease; LIHC cis rs7551222 0.752 rs10900596 chr1:204522457 T/C cg20240347 chr1:204465584 NA -0.35 -7.51 -0.38 5.04e-13 Schizophrenia; LIHC cis rs9916302 0.904 rs755500 chr17:37409865 C/T cg07936489 chr17:37558343 FBXL20 -0.8 -12.93 -0.57 2.05e-31 Glomerular filtration rate (creatinine); LIHC cis rs8078723 0.966 rs7021 chr17:38153875 T/A cg17467752 chr17:38218738 THRA 0.76 13.98 0.6 1.96e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs11190604 1.000 rs10786597 chr10:102291287 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.09 0.4 1.05e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg02951883 chr7:2050386 MAD1L1 -0.54 -8.12 -0.4 8.7e-15 Bipolar disorder and schizophrenia; LIHC cis rs74233809 1.000 rs11191515 chr10:104776527 G/A cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.4e-9 Birth weight; LIHC cis rs4474465 0.688 rs7945812 chr11:78280509 T/C cg27205649 chr11:78285834 NARS2 0.5 7.77 0.39 9.22e-14 Alzheimer's disease (survival time); LIHC cis rs1669338 0.588 rs7629889 chr3:3187643 C/T cg16797762 chr3:3221439 CRBN -0.87 -8.21 -0.41 4.66e-15 White matter integrity; LIHC cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.09e-10 Bipolar disorder; LIHC cis rs3806843 0.900 rs2531340 chr5:140131046 C/T cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1075232 1.000 rs16956707 chr15:31641633 G/A cg01030201 chr15:31746330 NA -0.78 -6.0 -0.31 5.07e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs1559088 0.948 rs2019603 chr19:33577367 C/T cg27124370 chr19:33622961 WDR88 -0.54 -8.75 -0.43 9.98e-17 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs75804782 0.641 rs11902599 chr2:239348400 C/T cg01134436 chr17:81009848 B3GNTL1 0.8 6.96 0.35 1.74e-11 Morning vs. evening chronotype;Chronotype; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22619719 chr1:1891578 KIAA1751 0.45 6.19 0.32 1.69e-9 Lung function (FEV1/FVC); LIHC cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg00149659 chr3:10157352 C3orf10 0.7 7.1 0.36 7.09e-12 Alzheimer's disease; LIHC cis rs36051895 0.589 rs6476947 chr9:5204279 A/G cg02405213 chr9:5042618 JAK2 -0.64 -10.69 -0.5 3.32e-23 Pediatric autoimmune diseases; LIHC cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg00166722 chr3:10149974 C3orf24 0.52 5.79 0.3 1.63e-8 Alzheimer's disease; LIHC cis rs6582630 0.638 rs12423236 chr12:38548162 G/A cg26384229 chr12:38710491 ALG10B -0.49 -6.79 -0.34 4.84e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs2806561 0.704 rs663942 chr1:23522476 G/A cg11953164 chr1:23521307 HTR1D 0.29 5.85 0.3 1.15e-8 Height; LIHC cis rs35306767 0.807 rs34885925 chr10:919032 G/C cg20503657 chr10:835505 NA 1.32 14.21 0.61 2.44e-36 Eosinophil percentage of granulocytes; LIHC cis rs7408868 0.908 rs4809028 chr19:15273231 A/G cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs1185460 0.967 rs11217133 chr11:118928249 G/A cg23280166 chr11:118938394 VPS11 0.56 7.4 0.37 1.07e-12 Coronary artery disease; LIHC cis rs7937682 0.889 rs497111 chr11:111499512 G/A cg09085632 chr11:111637200 PPP2R1B -1.03 -12.24 -0.55 7.9e-29 Primary sclerosing cholangitis; LIHC cis rs10193935 0.901 rs222486 chr2:42649664 C/T cg27598129 chr2:42591480 NA -0.69 -9.95 -0.47 1.22e-20 Colonoscopy-negative controls vs population controls; LIHC cis rs903552 1.000 rs8027380 chr15:102005810 T/C cg06707286 chr15:102010195 PCSK6 -0.44 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC cis rs243505 0.559 rs1558420 chr7:148480114 G/T cg09806900 chr7:148480153 CUL1 0.43 6.38 0.33 5.63e-10 Inflammatory bowel disease;Crohn's disease; LIHC trans rs8073060 0.586 rs226090 chr17:34034059 C/T cg19694781 chr19:47549865 TMEM160 -1.19 -12.21 -0.55 1.01e-28 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9783347 1.000 rs7947378 chr11:18381327 T/C cg15585147 chr11:18324498 HPS5 0.43 6.58 0.34 1.78e-10 Pancreatic cancer; LIHC cis rs7572733 0.515 rs1356542 chr2:198835702 G/T cg10820045 chr2:198174542 NA 0.48 7.31 0.37 1.91e-12 Dermatomyositis; LIHC trans rs1005277 0.522 rs7090858 chr10:38003670 A/C cg23533926 chr12:111358616 MYL2 0.32 6.41 0.33 4.96e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9640161 0.750 rs11764936 chr7:150025915 G/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.55 -9.29 -0.45 1.91e-18 Blood protein levels;Circulating chemerin levels; LIHC trans rs1728785 0.892 rs1170427 chr16:68603852 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs2279817 0.955 rs2270978 chr1:18023365 C/T cg21791023 chr1:18019539 ARHGEF10L 0.43 6.62 0.34 1.36e-10 Neuroticism; LIHC cis rs2455601 0.608 rs16906256 chr11:8887097 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -8.4 -0.41 1.22e-15 Schizophrenia; LIHC cis rs2625529 0.824 rs12903484 chr15:72299481 G/A cg16672083 chr15:72433130 SENP8 -0.3 -5.71 -0.3 2.41e-8 Red blood cell count; LIHC cis rs2191566 0.887 rs55703004 chr19:44504781 T/G cg20607764 chr19:44506953 ZNF230 -0.4 -6.16 -0.32 1.99e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs2180341 1.000 rs3798850 chr6:127613966 C/T cg27446573 chr6:127587934 RNF146 1.03 15.95 0.65 3.18e-43 Breast cancer; LIHC cis rs898097 1.000 rs898097 chr17:80904310 C/T cg15664640 chr17:80829946 TBCD 0.64 10.53 0.49 1.16e-22 Breast cancer; LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.23 -0.32 1.36e-9 Total body bone mineral density; LIHC cis rs2228479 0.702 rs12600047 chr16:89831630 G/A cg19635926 chr16:89946313 TCF25 0.48 6.04 0.31 3.95e-9 Skin colour saturation; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.6 0.62 6.99e-38 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg07424592 chr7:64974309 NA -0.8 -9.29 -0.45 1.82e-18 Diabetic kidney disease; LIHC cis rs7659604 0.521 rs13114801 chr4:122670855 C/A cg19671926 chr4:122722719 EXOSC9 0.46 6.76 0.34 6.06e-11 Type 2 diabetes; LIHC cis rs700651 0.752 rs1850631 chr2:198829468 T/G cg03934865 chr2:198174659 NA 0.47 6.92 0.35 2.24e-11 Intracranial aneurysm; LIHC cis rs6448317 0.911 rs10939013 chr4:24903015 G/A cg21108841 chr4:24914750 CCDC149 0.56 8.17 0.4 6.14e-15 Heschl's gyrus morphology; LIHC cis rs595982 0.527 rs17272673 chr19:49362992 C/A cg21252483 chr19:49399788 TULP2 -0.87 -9.86 -0.47 2.36e-20 Red cell distribution width; LIHC cis rs7539624 0.541 rs10916601 chr1:223897416 G/A cg07395969 chr1:223900822 CAPN2 0.49 5.82 0.3 1.38e-8 Schizophrenia; LIHC cis rs778371 0.723 rs12619195 chr2:233678326 G/A cg08000102 chr2:233561755 GIGYF2 -0.88 -14.63 -0.62 5.34e-38 Schizophrenia; LIHC cis rs9325144 0.647 rs12831609 chr12:39051576 C/A cg26384229 chr12:38710491 ALG10B -0.4 -5.77 -0.3 1.79e-8 Morning vs. evening chronotype; LIHC cis rs3096299 0.582 rs12935119 chr16:89542874 A/T cg02187348 chr16:89574699 SPG7 0.44 6.71 0.34 8.05e-11 Multiple myeloma (IgH translocation); LIHC cis rs1799949 0.602 rs8176235 chr17:41219560 C/T cg23758822 chr17:41437982 NA 0.85 14.45 0.62 2.94e-37 Menopause (age at onset); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01854420 chr3:99536702 MIR548G;C3orf26 -0.52 -6.4 -0.33 5.1e-10 Systolic blood pressure; LIHC cis rs9733 0.596 rs72702552 chr1:150677462 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.1e-9 Tonsillectomy; LIHC trans rs801193 1.000 rs7783924 chr7:66209057 A/C cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.89e-11 Aortic root size; LIHC cis rs12744310 0.887 rs1892420 chr1:41781410 C/T cg03962019 chr1:41807865 NA 0.39 6.23 0.32 1.36e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg08280861 chr8:58055591 NA 0.51 6.39 0.33 5.56e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19349861 chr11:133402246 OPCML -0.41 -6.21 -0.32 1.56e-9 Cognitive function; LIHC cis rs7927771 0.524 rs7110300 chr11:47848442 T/G cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC trans rs916888 0.773 rs199451 chr17:44801784 G/A cg22968622 chr17:43663579 NA 1.19 13.15 0.58 2.9e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs3540 0.512 rs11633872 chr15:91080512 G/A cg22089800 chr15:90895588 ZNF774 -0.53 -7.45 -0.37 7.8e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs11792861 0.781 rs72607158 chr9:111763010 T/C cg05043794 chr9:111880884 C9orf5 -0.32 -7.21 -0.36 3.56e-12 Menarche (age at onset); LIHC cis rs7677751 1.000 rs7677751 chr4:55124460 C/T cg17187183 chr4:55093834 PDGFRA 0.66 7.82 0.39 6.61e-14 Corneal astigmatism; LIHC cis rs6570726 0.818 rs952405 chr6:145925952 T/C cg23711669 chr6:146136114 FBXO30 0.62 10.58 0.5 8.27e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs11105298 0.891 rs10858852 chr12:89833338 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.37 -0.37 1.25e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7945705 0.719 rs2012680 chr11:8996059 G/A cg12365402 chr11:9010492 NRIP3 -0.33 -8.76 -0.43 8.93e-17 Hemoglobin concentration; LIHC cis rs1552244 0.572 rs58223482 chr3:10169746 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC cis rs34779708 0.771 rs12098283 chr10:35478115 G/T cg03585969 chr10:35415529 CREM 0.8 11.86 0.54 2.01e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs250677 0.958 rs43147 chr5:148417103 C/G cg18129178 chr5:148520854 ABLIM3 0.48 6.49 0.33 3.1e-10 Breast cancer; LIHC cis rs67981189 0.593 rs10132789 chr14:71480279 G/T cg15816911 chr14:71606274 NA 0.39 6.24 0.32 1.29e-9 Schizophrenia; LIHC cis rs9911578 0.967 rs8075786 chr17:56819216 T/C cg05425664 chr17:57184151 TRIM37 -0.58 -8.62 -0.42 2.6e-16 Intelligence (multi-trait analysis); LIHC cis rs9513627 0.749 rs73556149 chr13:100117012 G/A cg25919922 chr13:100150906 NA -0.75 -6.38 -0.33 5.91e-10 Obesity-related traits; LIHC cis rs3204270 0.516 rs62077189 chr17:79673088 G/A cg18367735 chr17:79674897 NA 0.64 7.83 0.39 6.13e-14 Dental caries; LIHC cis rs12497850 0.931 rs4974085 chr3:48924900 C/T cg20833759 chr3:49053208 WDR6;DALRD3 0.39 5.75 0.3 1.93e-8 Parkinson's disease; LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg14004847 chr7:1930337 MAD1L1 -0.47 -6.8 -0.34 4.82e-11 Bipolar disorder and schizophrenia; LIHC cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg02018176 chr4:1364513 KIAA1530 0.43 5.77 0.3 1.73e-8 Longevity; LIHC cis rs7312933 0.584 rs6582391 chr12:42634686 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 8.06 0.4 1.32e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7221595 0.877 rs7219437 chr17:4050138 A/G cg09695851 chr17:3907499 NA 0.46 5.82 0.3 1.37e-8 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; LIHC cis rs2228479 0.702 rs11076621 chr16:89837927 A/G cg14709524 chr16:89940631 TCF25 0.49 6.05 0.31 3.85e-9 Skin colour saturation; LIHC cis rs5769765 0.954 rs1569954 chr22:50244071 C/T cg26441486 chr22:50317300 CRELD2 -0.36 -6.65 -0.34 1.17e-10 Schizophrenia; LIHC cis rs875971 0.862 rs6960446 chr7:65733259 A/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg19774624 chr17:42201019 HDAC5 0.67 10.24 0.48 1.18e-21 Total body bone mineral density; LIHC cis rs35306767 0.903 rs11253475 chr10:907262 C/A cg20503657 chr10:835505 NA 1.07 12.08 0.55 3.31e-28 Eosinophil percentage of granulocytes; LIHC cis rs918629 0.761 rs6898371 chr5:95289333 A/G cg10483112 chr5:95245456 ELL2 -0.37 -6.48 -0.33 3.23e-10 IgG glycosylation; LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg08219700 chr8:58056026 NA 0.51 6.86 0.35 3.14e-11 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg00149659 chr3:10157352 C3orf10 0.66 6.81 0.35 4.32e-11 Alzheimer's disease; LIHC cis rs3812831 0.695 rs8000778 chr13:114944310 T/C cg08824895 chr13:115047677 UPF3A 0.5 7.25 0.37 2.71e-12 Schizophrenia; LIHC cis rs546131 0.642 rs1949048 chr11:34836974 G/A cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.28 -0.32 1.01e-9 Lung disease severity in cystic fibrosis; LIHC trans rs10506458 0.915 rs1463821 chr12:63402875 C/G cg03429785 chr15:59498649 MYO1E;LDHAL6B 0.66 9.7 0.46 8.07e-20 Hemostatic factors and hematological phenotypes; LIHC cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 8.44 0.42 9.2e-16 Platelet count; LIHC cis rs2380220 0.720 rs9398251 chr6:95984709 C/T cg04719120 chr6:96025338 MANEA 0.55 6.49 0.33 3.03e-10 Behavioural disinhibition (generation interaction); LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.19e-10 Developmental language disorder (linguistic errors); LIHC cis rs644799 1.000 rs3748256 chr11:95521953 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.41 5.78 0.3 1.68e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs875971 0.706 rs1643374 chr7:65872682 T/A cg18876405 chr7:65276391 NA 0.45 7.48 0.37 6.36e-13 Aortic root size; LIHC cis rs2304069 0.779 rs245080 chr5:149354805 A/G cg12661370 chr5:149340060 SLC26A2 -0.54 -7.37 -0.37 1.27e-12 HIV-1 control; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00586367 chr8:74790437 UBE2W 0.49 7.05 0.36 9.93e-12 Cognitive function; LIHC cis rs10078 0.528 rs2434697 chr5:466811 T/C cg07599136 chr5:415885 AHRR 0.77 12.56 0.56 5.28e-30 Fat distribution (HIV); LIHC cis rs896854 0.967 rs896853 chr8:95960855 G/C cg13393036 chr8:95962371 TP53INP1 -0.46 -10.95 -0.51 3.89e-24 Type 2 diabetes; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg14893161 chr1:205819251 PM20D1 0.66 9.61 0.46 1.59e-19 Menarche (age at onset); LIHC cis rs6502050 0.835 rs8075086 chr17:80092649 A/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.93e-9 Life satisfaction; LIHC cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.06 0.55 3.67e-28 Alzheimer's disease; LIHC cis rs860295 1.000 rs7541060 chr1:155728088 A/T cg02153340 chr1:155202674 NA -0.31 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs763121 0.853 rs8138996 chr22:39047435 G/T cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs35110281 0.811 rs4819264 chr21:45017349 G/T cg21573476 chr21:45109991 RRP1B -0.56 -10.56 -0.5 9.29e-23 Mean corpuscular volume; LIHC trans rs116095464 0.558 rs55776650 chr5:273826 G/A cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs9420 0.961 rs12807250 chr11:57600285 C/T cg19752551 chr11:57585705 CTNND1 -0.5 -6.88 -0.35 2.87e-11 Schizophrenia; LIHC cis rs1008375 0.900 rs13144986 chr4:17675019 C/A cg16339924 chr4:17578868 LAP3 -0.48 -6.23 -0.32 1.39e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19040509 chr17:72199640 RPL38 0.41 6.04 0.31 3.98e-9 Pancreatic cancer; LIHC cis rs6988636 1.000 rs28624331 chr8:124190768 G/A cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs597539 0.652 rs579136 chr11:68637476 C/G cg06028808 chr11:68637592 NA 0.43 5.84 0.3 1.21e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs2727020 0.538 rs11040373 chr11:49461791 T/C cg03929089 chr4:120376271 NA -0.52 -8.36 -0.41 1.63e-15 Coronary artery disease; LIHC cis rs1577917 0.958 rs34765423 chr6:86484448 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.23 -0.48 1.32e-21 Response to antipsychotic treatment; LIHC cis rs11696739 0.835 rs6074894 chr20:1597050 G/A cg15722679 chr20:1638393 SIRPG 0.41 7.83 0.39 5.98e-14 Mean platelet volume; LIHC cis rs9486715 1.000 rs6899647 chr6:97065661 A/G cg18709589 chr6:96969512 KIAA0776 -0.35 -6.1 -0.31 2.92e-9 Headache; LIHC cis rs67478160 0.643 rs11847468 chr14:104220295 G/A cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.61 -0.38 2.66e-13 Schizophrenia; LIHC cis rs875971 0.619 rs10278371 chr7:66051540 C/A cg00343986 chr7:65444356 GUSB -0.41 -6.04 -0.31 4.1e-9 Aortic root size; LIHC trans rs11088226 0.681 rs2833901 chr21:33939318 T/C cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.06e-34 Gastritis; LIHC cis rs2806561 0.765 rs679591 chr1:23499916 T/C cg19743168 chr1:23544995 NA 0.36 6.05 0.31 3.74e-9 Height; LIHC cis rs2153535 0.580 rs7743418 chr6:8438128 A/C cg07606381 chr6:8435919 SLC35B3 0.79 11.54 0.53 3.17e-26 Motion sickness; LIHC cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.91 0.35 2.34e-11 Gut microbiome composition (summer); LIHC cis rs5753618 0.539 rs2106294 chr22:31645759 C/T cg07713946 chr22:31675144 LIMK2 -0.42 -7.55 -0.38 3.89e-13 Colorectal cancer; LIHC cis rs9464760 0.527 rs9476759 chr6:15158709 T/C cg15799072 chr6:15248335 JARID2 0.58 5.75 0.3 1.97e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2070488 0.965 rs7372849 chr3:38524328 G/C cg24069376 chr3:38537580 EXOG 0.41 7.57 0.38 3.56e-13 Electrocardiographic conduction measures; LIHC cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1568889 0.938 rs12795971 chr11:28355104 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.9 0.35 2.48e-11 Bipolar disorder; LIHC cis rs4474465 0.646 rs4945301 chr11:78283362 A/G cg02023728 chr11:77925099 USP35 -0.34 -6.01 -0.31 4.72e-9 Alzheimer's disease (survival time); LIHC cis rs826838 0.967 rs11169387 chr12:39145737 C/T cg26384229 chr12:38710491 ALG10B 0.88 11.47 0.53 5.27e-26 Heart rate; LIHC cis rs72781680 0.898 rs72798049 chr2:23958002 C/G cg08917208 chr2:24149416 ATAD2B 0.83 7.63 0.38 2.42e-13 Lymphocyte counts; LIHC cis rs7100689 0.646 rs10749581 chr10:82141651 A/G cg00277334 chr10:82204260 NA 0.58 7.45 0.37 7.53e-13 Post bronchodilator FEV1; LIHC cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg12310025 chr6:25882481 NA -0.94 -13.65 -0.59 3.67e-34 Blood metabolite levels; LIHC cis rs4332037 1.000 rs6947019 chr7:1950337 G/A cg23422044 chr7:1970798 MAD1L1 -0.62 -7.12 -0.36 6.35e-12 Bipolar disorder; LIHC cis rs7772486 0.790 rs9497424 chr6:146225271 C/A cg13319975 chr6:146136371 FBXO30 0.35 5.77 0.3 1.79e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6430585 0.528 rs309154 chr2:136726567 C/T cg25344623 chr2:136566232 LCT -0.37 -5.97 -0.31 5.89e-9 Corneal structure; LIHC cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg23205692 chr1:25664452 TMEM50A 0.4 6.35 0.32 6.75e-10 Plateletcrit;Mean corpuscular volume; LIHC cis rs10612751 1 rs10612751 chr13:107646032 CTG/C cg06614754 chr13:107569395 NA 0.33 6.23 0.32 1.34e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17253792 0.822 rs76264681 chr14:56060447 T/C cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs2228479 0.850 rs1800339 chr16:89839637 C/A cg00800038 chr16:89945340 TCF25 -0.62 -9.35 -0.45 1.2e-18 Skin colour saturation; LIHC cis rs2070488 0.965 rs2366123 chr3:38493153 G/A cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19906760 chr14:78227687 SNW1;C14orf178 0.42 6.62 0.34 1.35e-10 Pancreatic cancer; LIHC cis rs3770081 0.590 rs6747424 chr2:86176224 G/A cg01119172 chr2:86362222 SNORD94;PTCD3 0.39 5.83 0.3 1.27e-8 Facial emotion recognition (sad faces); LIHC cis rs11229555 0.645 rs7945992 chr11:58187755 T/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs79387448 0.745 rs72993754 chr2:103151136 A/G cg09003973 chr2:102972529 NA 0.8 7.05 0.36 1.02e-11 Gut microbiota (bacterial taxa); LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg07677032 chr17:61819896 STRADA 0.43 6.2 0.32 1.62e-9 Prudent dietary pattern; LIHC cis rs7100689 0.577 rs10788545 chr10:82034675 A/G cg00277334 chr10:82204260 NA -0.49 -5.85 -0.3 1.13e-8 Post bronchodilator FEV1; LIHC cis rs2075671 0.857 rs11772849 chr7:100308412 G/A cg16850897 chr7:100343110 ZAN -0.39 -5.72 -0.3 2.33e-8 Other erythrocyte phenotypes; LIHC cis rs79149102 0.579 rs74023936 chr15:75362084 C/T cg15902774 chr15:75289873 SCAMP5 0.4 5.99 0.31 5.3300000000000004e-09 Lung cancer; LIHC cis rs2404602 0.716 rs7179142 chr15:76698268 G/A cg03037974 chr15:76606532 NA 0.79 16.37 0.66 6.87e-45 Blood metabolite levels; LIHC cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs13161895 1.000 rs4389651 chr5:179460968 T/A cg06664874 chr5:179499304 RNF130 0.58 7.08 0.36 8.06e-12 LDL cholesterol; LIHC cis rs1401999 0.898 rs4148561 chr3:183726379 A/G cg20387954 chr3:183756860 HTR3D 0.28 5.9 0.3 8.59e-9 Anterior chamber depth; LIHC cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg25894440 chr7:65020034 NA -0.53 -6.04 -0.31 4.05e-9 Diabetic kidney disease; LIHC cis rs7618501 0.633 rs11130228 chr3:50003246 C/T cg21467203 chr3:49911342 NA -0.46 -8.54 -0.42 4.46e-16 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02978959 chr19:57791520 ZNF460 0.46 6.39 0.33 5.56e-10 Lung function (FEV1/FVC); LIHC cis rs9486719 0.948 rs2092095 chr6:96870864 T/G cg06623918 chr6:96969491 KIAA0776 0.74 7.29 0.37 2.22e-12 Migraine;Coronary artery disease; LIHC cis rs950169 0.840 rs12905223 chr15:85114268 T/C cg03959625 chr15:84868606 LOC388152 0.43 5.89 0.3 9.45e-9 Schizophrenia; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg24846343 chr22:24311635 DDTL 0.64 12.19 0.55 1.22e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9916302 0.904 rs9894500 chr17:37515735 G/C cg07936489 chr17:37558343 FBXL20 0.81 12.96 0.57 1.6e-31 Glomerular filtration rate (creatinine); LIHC cis rs12887734 0.524 rs12888002 chr14:104238647 T/C cg24130564 chr14:104152367 KLC1 -0.44 -7.26 -0.37 2.63e-12 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs3096299 0.935 rs3102387 chr16:89432276 A/C cg02187348 chr16:89574699 SPG7 0.46 6.67 0.34 1.03e-10 Multiple myeloma (IgH translocation); LIHC cis rs17685 0.725 rs6947068 chr7:75662056 T/C cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.22 0.32 1.49e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1843834 0.858 rs6731785 chr2:225491143 A/G cg22455342 chr2:225449267 CUL3 0.47 6.1 0.31 2.95e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg12016809 chr21:47604291 C21orf56 0.4 5.95 0.31 6.75e-9 Testicular germ cell tumor; LIHC cis rs4073582 0.595 rs1151540 chr11:66041807 A/C cg14036092 chr11:66035641 RAB1B 0.46 6.85 0.35 3.38e-11 Gout; LIHC cis rs12188164 0.543 rs890972 chr5:462465 C/A cg26076054 chr5:421317 AHRR 0.27 5.97 0.31 5.91e-9 Cystic fibrosis severity; LIHC trans rs3960554 0.808 rs112962015 chr7:75659303 C/T cg19862616 chr7:65841803 NCRNA00174 0.59 8.17 0.4 6.2e-15 Eotaxin levels; LIHC cis rs3790844 0.613 rs12030331 chr1:200001547 G/A cg13229857 chr1:200006247 NR5A2 0.37 6.07 0.31 3.35e-9 Pancreatic cancer; LIHC cis rs7528419 1.000 rs12740374 chr1:109817590 G/T cg06804625 chr1:109812012 CELSR2 0.41 6.02 0.31 4.53e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs6463523 0.933 rs4724821 chr7:762544 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.98 17.9 0.7 4.83e-51 Subjective well-being; LIHC cis rs4975616 0.773 rs414965 chr5:1324121 G/A cg07493874 chr5:1342172 CLPTM1L -0.66 -10.62 -0.5 5.96e-23 Lung cancer; LIHC cis rs7107174 0.688 rs881361 chr11:78128047 C/G cg02023728 chr11:77925099 USP35 0.41 7.33 0.37 1.69e-12 Testicular germ cell tumor; LIHC cis rs11663156 0.534 rs12957181 chr18:50901617 A/G cg24270629 chr18:50823537 DCC 0.45 6.17 0.32 1.96e-9 Intelligence (multi-trait analysis); LIHC cis rs8062405 0.789 rs1968751 chr16:28631759 T/C cg07382826 chr16:28625726 SULT1A1 -0.45 -6.49 -0.33 3e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs637571 0.546 rs10791827 chr11:65596546 C/A cg04055107 chr11:65626734 MUS81;CFL1 -0.46 -6.99 -0.35 1.4e-11 Eosinophil percentage of white cells; LIHC cis rs35306767 0.951 rs55742421 chr10:961037 A/C cg26597838 chr10:835615 NA 1.18 12.71 0.57 1.35e-30 Eosinophil percentage of granulocytes; LIHC cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg24209194 chr3:40518798 ZNF619 0.53 7.52 0.38 4.8e-13 Renal cell carcinoma; LIHC cis rs7586673 0.866 rs747003 chr2:161916409 C/T cg22496339 chr2:162101262 NA -0.66 -9.99 -0.48 8.62e-21 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg12516959 chr21:47718080 NA -0.36 -5.84 -0.3 1.21e-8 Testicular germ cell tumor; LIHC cis rs9640161 0.659 rs7788316 chr7:150013995 A/T cg17279839 chr7:150038598 RARRES2 0.47 10.01 0.48 7.46e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs10193935 1.000 rs57883795 chr2:42387926 C/T cg27598129 chr2:42591480 NA -0.71 -9.61 -0.46 1.67e-19 Colonoscopy-negative controls vs population controls; LIHC cis rs9318086 0.776 rs1326130 chr13:24447664 A/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.54 10.8 0.5 1.35e-23 Myopia (pathological); LIHC trans rs72960926 0.744 rs11759133 chr6:74932518 A/G cg07247405 chr1:2484626 LOC115110 0.55 6.58 0.34 1.75e-10 Metabolite levels (MHPG); LIHC cis rs2070488 1.000 rs7373816 chr3:38490443 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC cis rs2303759 0.543 rs7255778 chr19:49906608 G/A cg22307029 chr19:49891270 CCDC155 0.59 9.54 0.46 2.85e-19 Multiple sclerosis; LIHC cis rs6708331 0.517 rs12992553 chr2:70360262 A/G cg01613454 chr2:70366299 NA 0.38 6.11 0.31 2.75e-9 Obesity-related traits; LIHC cis rs7238033 0.602 rs8088163 chr18:43309809 T/C cg20610511 chr18:43302872 SLC14A1 0.39 6.46 0.33 3.55e-10 Bladder cancer; LIHC cis rs17685 0.697 rs2302437 chr7:75677016 G/A cg16684958 chr7:75615977 POR -0.51 -8.37 -0.41 1.45e-15 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21107223 chr15:75182455 MPI -0.44 -6.33 -0.32 7.79e-10 Cognitive function; LIHC cis rs10751667 0.666 rs7124480 chr11:971601 G/A ch.11.42038R chr11:967971 AP2A2 0.55 10.02 0.48 7.03e-21 Alzheimer's disease (late onset); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg24588891 chr3:9848638 ARPC4 0.39 6.07 0.31 3.49e-9 Immature fraction of reticulocytes; LIHC trans rs668210 0.793 rs522553 chr11:65771669 T/C cg17712092 chr4:129076599 LARP1B 0.6 6.43 0.33 4.34e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs7618501 0.699 rs6446187 chr3:49907111 C/A cg24110177 chr3:50126178 RBM5 -0.51 -7.94 -0.39 2.84e-14 Intelligence (multi-trait analysis); LIHC cis rs9896052 0.614 rs4789201 chr17:73440579 A/G cg25649188 chr17:73499917 CASKIN2 0.43 6.81 0.35 4.32e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs4938330 0.681 rs12271169 chr11:116980021 C/G cg01368799 chr11:117014884 PAFAH1B2 -0.47 -6.38 -0.33 5.62e-10 Blood protein levels; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg19139277 chr8:28243953 ZNF395 -0.56 -6.09 -0.31 3.01e-9 Preeclampsia; LIHC cis rs611744 0.647 rs615233 chr8:109254262 C/T cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg10869401 chr11:129802046 PRDM10 -0.39 -6.12 -0.31 2.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.889 rs585545 chr1:109841662 A/T cg16275483 chr1:110013120 SYPL2 -0.5 -6.16 -0.32 2.04e-9 Intelligence (multi-trait analysis); LIHC cis rs17854409 0.881 rs12625401 chr20:61472939 A/T cg07645718 chr20:61493192 TCFL5 0.79 6.56 0.33 2.03e-10 Obesity-related traits; LIHC cis rs72772090 0.710 rs17400685 chr5:96066366 A/C cg17330273 chr5:96107758 CAST;ERAP1 0.71 8.2 0.41 5.03e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10504229 0.817 rs60646469 chr8:58195348 T/C cg21724239 chr8:58056113 NA 0.48 5.78 0.3 1.66e-8 Developmental language disorder (linguistic errors); LIHC trans rs2262909 0.925 rs73019838 chr19:22247732 T/A cg05197062 chr11:11642011 GALNTL4 0.42 6.08 0.31 3.17e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC trans rs9528384 0.927 rs4886357 chr13:62234016 G/C cg20705804 chr7:43590176 HECW1 0.55 6.1 0.31 2.82e-9 Verbal declarative memory; LIHC cis rs10420951 0.617 rs8101992 chr19:18614423 A/G cg10790698 chr19:18539756 SSBP4 -0.42 -5.92 -0.3 7.93e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7582180 0.563 rs4851304 chr2:100963871 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.58 0.42 3.3e-16 Intelligence (multi-trait analysis); LIHC cis rs7187994 0.848 rs16974515 chr16:84782510 T/G cg07647771 chr16:84786436 USP10 -0.33 -6.46 -0.33 3.51e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs769267 1.000 rs7246748 chr19:19433105 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.62 -10.08 -0.48 4.34e-21 Tonsillectomy; LIHC trans rs2363709 1.000 rs2363714 chr3:67421846 C/G cg22969669 chr19:19613165 GATAD2A -0.66 -6.13 -0.31 2.48e-9 IgE levels; LIHC cis rs703842 0.963 rs923829 chr12:58174306 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.82 13.57 0.59 7.62e-34 Multiple sclerosis; LIHC cis rs1707322 0.752 rs61784793 chr1:46149285 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.4 0.37 1.08e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2727020 0.612 rs603672 chr11:49234566 T/A cg15704280 chr7:45808275 SEPT13 0.88 16.12 0.66 6.65e-44 Coronary artery disease; LIHC cis rs9430161 0.579 rs9659356 chr1:11034817 A/G cg27631724 chr1:11040367 C1orf127 0.36 6.65 0.34 1.19e-10 Ewing sarcoma; LIHC cis rs881375 0.678 rs10760125 chr9:123662590 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.37 0.33 5.96e-10 Rheumatoid arthritis; LIHC cis rs600806 0.778 rs891379 chr1:110003605 A/G cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.31 -0.37 1.87e-12 Intelligence (multi-trait analysis); LIHC cis rs2404602 1.000 rs2404602 chr15:77030792 A/G cg03037974 chr15:76606532 NA 0.71 13.87 0.6 5.27e-35 Blood metabolite levels; LIHC cis rs782590 0.537 rs7575170 chr2:55886780 C/T cg18811423 chr2:55921094 PNPT1 -0.53 -7.93 -0.39 3.07e-14 Metabolic syndrome; LIHC cis rs769267 0.930 rs1054284 chr19:19616953 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.5 7.55 0.38 3.97e-13 Tonsillectomy; LIHC cis rs11608355 0.515 rs12818537 chr12:109902150 C/T cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs9814567 0.727 rs7430034 chr3:134342127 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.54 -8.74 -0.43 1.09e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg26531700 chr6:26746687 NA 0.37 6.15 0.32 2.21e-9 Intelligence (multi-trait analysis); LIHC cis rs1215050 0.740 rs783932 chr4:98973936 C/G cg05340658 chr4:99064831 C4orf37 -0.4 -6.17 -0.32 1.91e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.3 0.45 1.74e-18 Bipolar disorder; LIHC cis rs17776563 0.887 rs28773595 chr15:89128232 A/G cg05013243 chr15:89149849 MIR1179 0.4 6.65 0.34 1.19e-10 Thyroid hormone levels; LIHC cis rs9649465 1.000 rs3807640 chr7:123338713 G/C cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.18e-15 Migraine; LIHC cis rs7131987 0.903 rs11050162 chr12:29420054 T/G cg00204748 chr12:29376779 FAR2 0.41 7.6 0.38 2.81e-13 QT interval; LIHC cis rs10751667 0.666 rs10794354 chr11:954615 A/T ch.11.42038R chr11:967971 AP2A2 0.56 10.09 0.48 4.1e-21 Alzheimer's disease (late onset); LIHC trans rs1005277 0.579 rs2474584 chr10:38416389 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.25 0.32 1.24e-9 Extrinsic epigenetic age acceleration; LIHC cis rs10870270 1.000 rs10870232 chr10:133738537 T/G cg26149184 chr10:133730230 NA 0.45 7.16 0.36 4.83e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7945705 0.935 rs2568062 chr11:8887945 A/G cg12365402 chr11:9010492 NRIP3 -0.24 -6.19 -0.32 1.72e-9 Hemoglobin concentration; LIHC trans rs6952808 0.929 rs12532128 chr7:1925454 T/C cg04565464 chr8:145669602 NFKBIL2 0.38 6.12 0.31 2.54e-9 Bipolar disorder and schizophrenia; LIHC cis rs769267 0.930 rs6511038 chr19:19607564 A/C cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.2 0.32 1.58e-9 Tonsillectomy; LIHC cis rs2070488 1.000 rs2268753 chr3:38500189 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.13 0.66 6.33e-44 Electrocardiographic conduction measures; LIHC cis rs1552244 0.554 rs3732964 chr3:10048839 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs11711311 0.955 rs10934247 chr3:113534941 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.41 7.58 0.38 3.31e-13 IgG glycosylation; LIHC trans rs2727020 0.619 rs11040300 chr11:49269984 C/A cg15704280 chr7:45808275 SEPT13 0.76 10.97 0.51 3.3e-24 Coronary artery disease; LIHC cis rs116248771 0.739 rs6768636 chr3:158347565 C/T cg16708174 chr3:158430962 RARRES1 -0.49 -6.55 -0.33 2.18e-10 diarrhoeal disease at age 2; LIHC cis rs10751667 0.643 rs10794352 chr11:946294 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.12 0.48 3.02e-21 Alzheimer's disease (late onset); LIHC cis rs7945705 0.782 rs3763918 chr11:8819683 T/A cg21881798 chr11:8931708 C11orf17;ST5 0.43 7.22 0.36 3.31e-12 Hemoglobin concentration; LIHC cis rs11098499 0.863 rs7695620 chr4:120452776 G/A cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs6500602 0.727 rs11644481 chr16:4581002 T/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.8 0.3 1.49e-8 Schizophrenia; LIHC cis rs6840360 0.615 rs6831810 chr4:152461995 A/G cg22705602 chr4:152727874 NA -0.32 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs1403694 1.000 rs2689197 chr3:186438346 C/T cg12454167 chr3:186435060 KNG1 0.29 7.05 0.36 1.02e-11 Blood protein levels; LIHC cis rs798554 0.797 rs35957220 chr7:2812632 C/G cg13628971 chr7:2884303 GNA12 0.52 7.69 0.38 1.56e-13 Height; LIHC cis rs67311347 1.000 rs1466236 chr3:40462162 C/T cg00656387 chr3:40428638 ENTPD3 0.44 7.46 0.37 7.03e-13 Renal cell carcinoma; LIHC cis rs763121 0.853 rs6519119 chr22:38989007 C/G cg14440974 chr22:39074834 NA -0.44 -6.98 -0.35 1.58e-11 Menopause (age at onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14279899 chr6:137540774 IFNGR1 -0.41 -6.12 -0.31 2.5e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11711311 1.000 rs1073040 chr3:113522123 C/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.1 0.4 9.79e-15 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27130769 chr7:5417105 TNRC18 0.45 6.68 0.34 9.81e-11 Pancreatic cancer; LIHC cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg20607798 chr8:58055168 NA 0.5 6.24 0.32 1.29e-9 Developmental language disorder (linguistic errors); LIHC cis rs4629710 0.592 rs9492868 chr6:131542238 A/C cg12606694 chr6:131520996 AKAP7 0.62 7.22 0.36 3.39e-12 Multiple myeloma (IgH translocation); LIHC cis rs2115630 0.936 rs8033459 chr15:85253258 C/T cg11189052 chr15:85197271 WDR73 -0.4 -5.91 -0.3 8.46e-9 P wave terminal force; LIHC cis rs2455799 0.613 rs4684259 chr3:15791279 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs11098499 0.955 rs13113112 chr4:120156040 C/T cg09307838 chr4:120376055 NA 0.75 10.9 0.51 6e-24 Corneal astigmatism; LIHC cis rs2075371 1.000 rs432487 chr7:133990114 T/G cg11752832 chr7:134001865 SLC35B4 0.52 7.83 0.39 6.14e-14 Mean platelet volume; LIHC cis rs2439831 0.867 rs8039638 chr15:43634405 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.31 0.52 2.11e-25 Lung cancer in ever smokers; LIHC cis rs7586673 0.930 rs7591506 chr2:161960925 T/G cg22496339 chr2:162101262 NA 0.7 10.61 0.5 6.25e-23 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.720 rs6931553 chr6:146112348 T/C cg23711669 chr6:146136114 FBXO30 -0.76 -13.64 -0.59 3.94e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 0.755 rs62034355 chr16:28581038 G/C cg00204512 chr16:28754710 NA 0.42 7.12 0.36 6.21e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7312933 0.558 rs7305397 chr12:42850058 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 8.03 0.4 1.57e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7539409 0.604 rs910183 chr1:84297285 A/G cg10977910 chr1:84465055 TTLL7 0.69 7.05 0.36 1.01e-11 Alzheimer's disease; LIHC cis rs12477438 0.501 rs17759607 chr2:99737005 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.13 0.61 5.14e-36 Chronic sinus infection; LIHC cis rs796364 1.000 rs769949 chr2:200729558 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.73 8.52 0.42 5.06e-16 Schizophrenia; LIHC cis rs12458462 0.851 rs3859317 chr18:77443093 A/C cg11879182 chr18:77439856 CTDP1 0.86 14.88 0.63 5.89e-39 Monocyte count; LIHC cis rs35362007 0.530 rs17835086 chr14:96012465 A/G cg13511115 chr14:96000878 GLRX5;SNHG10;SCARNA13 0.79 6.64 0.34 1.22e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7577696 0.525 rs2366547 chr2:32251109 G/A cg02381751 chr2:32503542 YIPF4 -0.43 -5.96 -0.31 6.12e-9 Inflammatory biomarkers; LIHC cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.05 0.4 1.38e-14 Platelet count; LIHC cis rs1664789 1.000 rs1664787 chr5:53282149 A/G ch.5.1024479R chr5:53302184 ARL15 0.53 8.68 0.42 1.61e-16 Waist circumference adjusted for body mass index; LIHC cis rs508618 0.731 rs12033229 chr1:231545703 T/C cg06096015 chr1:231504339 EGLN1 -0.43 -7.26 -0.37 2.64e-12 Red blood cell count; LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg05484376 chr2:27715224 FNDC4 0.39 6.5 0.33 2.78e-10 Menopause (age at onset); LIHC cis rs10242455 0.571 rs55830753 chr7:99292222 A/G cg18809830 chr7:99032528 PTCD1 -0.83 -6.62 -0.34 1.42e-10 Blood metabolite levels; LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs4820294 0.669 rs9622677 chr22:38054262 A/C cg00292662 chr22:38071168 LGALS1 0.39 6.63 0.34 1.35e-10 Fat distribution (HIV); LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs7197653 0.667 rs7190070 chr16:68353983 C/T cg09835421 chr16:68378352 PRMT7 -0.88 -10.26 -0.48 1.07e-21 Magnesium levels; LIHC trans rs634534 0.622 rs624273 chr11:65712413 A/G cg17712092 chr4:129076599 LARP1B 0.65 9.5 0.46 3.68e-19 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02895995 chr19:7554069 PEX11G 0.43 6.61 0.34 1.48e-10 Pancreatic cancer; LIHC cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg00149659 chr3:10157352 C3orf10 0.7 7.21 0.36 3.69e-12 Alzheimer's disease; LIHC cis rs9443189 0.570 rs569731 chr6:76357593 G/A cg01950844 chr6:76311363 SENP6 0.88 10.89 0.51 6.3e-24 Prostate cancer; LIHC cis rs2580764 0.503 rs2972097 chr2:55267545 T/C cg09592903 chr2:55203963 RTN4 0.7 13.13 0.58 3.66e-32 Mean platelet volume; LIHC cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg05368731 chr17:41323189 NBR1 0.72 12.33 0.55 3.63e-29 Menopause (age at onset); LIHC cis rs9921222 0.521 rs78867928 chr16:368986 C/T cg26944245 chr16:421049 TMEM8A;MRPL28 0.42 6.83 0.35 3.85e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs7100689 0.622 rs2994389 chr10:82062257 C/G cg00277334 chr10:82204260 NA -0.6 -7.53 -0.38 4.49e-13 Post bronchodilator FEV1; LIHC cis rs7258465 1.000 rs271624 chr19:18627953 A/G cg01065977 chr19:18549689 ISYNA1 -0.39 -6.05 -0.31 3.71e-9 Breast cancer; LIHC cis rs10751667 0.666 rs7103585 chr11:971166 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs1048238 0.506 rs848210 chr1:16259813 A/G cg00529422 chr1:16285251 ZBTB17 0.33 6.0 0.31 4.92e-9 Systolic blood pressure; LIHC cis rs6089584 0.888 rs6142927 chr20:60605848 A/G cg06108461 chr20:60628389 TAF4 -0.99 -15.36 -0.64 7.65e-41 Body mass index; LIHC cis rs11608355 0.545 rs36094325 chr12:109911542 A/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs73001065 0.901 rs73004933 chr19:19675696 C/T cg03709012 chr19:19516395 GATAD2A 0.9 7.84 0.39 5.65e-14 LDL cholesterol; LIHC cis rs8044995 0.563 rs7190134 chr16:68381516 A/G cg05110241 chr16:68378359 PRMT7 0.88 9.97 0.47 1e-20 Schizophrenia; LIHC cis rs2635047 1.000 rs2635047 chr18:44736336 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.49 6.48 0.33 3.25e-10 Educational attainment; LIHC cis rs1707322 0.686 rs1547924 chr1:46085112 C/T cg03146154 chr1:46216737 IPP 0.57 9.56 0.46 2.44e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7904368 0.754 rs7076955 chr10:16852781 G/A cg14835575 chr10:16859367 RSU1 0.64 9.02 0.44 1.34e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs4713118 0.868 rs35069907 chr6:27746692 T/C cg20933634 chr6:27740509 NA 0.48 6.21 0.32 1.58e-9 Parkinson's disease; LIHC cis rs4930103 0.602 rs170101 chr11:2008936 C/T cg06197492 chr11:2016605 H19 0.39 6.33 0.32 7.68e-10 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs7647973 0.961 rs7638750 chr3:49452957 A/T cg07636037 chr3:49044803 WDR6 -0.54 -6.66 -0.34 1.1e-10 Menarche (age at onset); LIHC cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg20607798 chr8:58055168 NA 0.67 8.37 0.41 1.5e-15 Developmental language disorder (linguistic errors); LIHC cis rs8016982 0.651 rs9806027 chr14:81668707 G/C cg01989461 chr14:81687754 GTF2A1 0.63 12.77 0.57 8.51e-31 Schizophrenia; LIHC cis rs7772486 0.720 rs4896837 chr6:146014168 C/T cg05347473 chr6:146136440 FBXO30 -0.37 -5.9 -0.3 8.79e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.679 rs16921677 chr8:58052431 T/C cg02290350 chr8:58132656 NA 0.32 6.91 0.35 2.35e-11 Developmental language disorder (linguistic errors); LIHC cis rs6540556 0.723 rs11487866 chr1:209892046 G/A cg05527609 chr1:210001259 C1orf107 -0.54 -7.52 -0.38 4.9e-13 Red blood cell count; LIHC cis rs8067354 0.957 rs9896742 chr17:57826530 T/G cg02344993 chr17:57696989 CLTC 0.55 8.79 0.43 7.41e-17 Hemoglobin concentration; LIHC cis rs151997 0.962 rs56170692 chr5:50247928 G/A cg06027927 chr5:50259733 NA 0.6 7.87 0.39 4.86e-14 Callous-unemotional behaviour; LIHC cis rs7666738 0.518 rs13133925 chr4:98706398 G/T cg05340658 chr4:99064831 C4orf37 0.49 6.38 0.33 5.82e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs1862618 0.671 rs2591955 chr5:56244948 C/T cg12311346 chr5:56204834 C5orf35 0.44 5.99 0.31 5.44e-9 Initial pursuit acceleration; LIHC cis rs5769765 0.671 rs138841 chr22:50181960 C/A cg02269571 chr22:50332266 NA -0.59 -7.97 -0.4 2.32e-14 Schizophrenia; LIHC cis rs3812831 0.654 rs6560933 chr13:114937294 A/G cg06611532 chr13:114900021 NA -0.37 -6.88 -0.35 2.83e-11 Schizophrenia; LIHC cis rs2072499 0.778 rs41265025 chr1:156163906 C/T cg24450063 chr1:156163899 SLC25A44 0.75 8.12 0.4 8.49e-15 Testicular germ cell tumor; LIHC cis rs7131987 0.903 rs67517901 chr12:29421346 A/G cg21486233 chr12:29375141 FAR2 0.29 5.72 0.3 2.27e-8 QT interval; LIHC cis rs2963155 0.518 rs862489 chr5:142634355 T/C cg17617527 chr5:142782415 NR3C1 0.82 9.13 0.44 6.29e-18 Breast cancer; LIHC trans rs1814175 0.817 rs1996982 chr11:49972619 G/T cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC trans rs61931739 0.500 rs11053273 chr12:34547255 C/T cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg12386194 chr3:101231763 SENP7 0.47 7.01 0.35 1.25e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs637571 0.546 rs11227311 chr11:65585257 C/A cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.53 -0.33 2.39e-10 Eosinophil percentage of white cells; LIHC cis rs6426558 0.537 rs10495253 chr1:227471820 A/T cg10327440 chr1:227177885 CDC42BPA 0.41 6.34 0.32 7.23e-10 Neutrophil percentage of white cells; LIHC cis rs2153535 0.580 rs1414345 chr6:8471537 T/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.53 -7.52 -0.38 4.74e-13 Lymphocyte counts; LIHC cis rs2976388 0.967 rs2976395 chr8:143763750 G/A cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs1144333 0.655 rs77244403 chr1:76304872 A/G cg22875332 chr1:76189707 ACADM 0.44 6.62 0.34 1.42e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs1707322 1.000 rs7519181 chr1:46387829 G/C cg03146154 chr1:46216737 IPP 0.47 7.62 0.38 2.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg17971929 chr21:40555470 PSMG1 0.8 9.65 0.46 1.16e-19 Cognitive function; LIHC cis rs6973256 0.569 rs6944149 chr7:133381365 A/C cg10665199 chr7:133106180 EXOC4 0.35 6.09 0.31 3.08e-9 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.61 0.8 1.12e-77 Prudent dietary pattern; LIHC cis rs6570726 0.935 rs424263 chr6:145840073 A/C cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs10911232 0.507 rs4651138 chr1:183001312 C/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs9611519 0.780 rs1983631 chr22:41644074 C/T cg03806693 chr22:41940476 POLR3H -0.65 -7.72 -0.39 1.3e-13 Neuroticism; LIHC cis rs1552244 0.832 rs61056817 chr3:10027641 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.63 -9.48 -0.46 4.56e-19 Alzheimer's disease; LIHC cis rs3818285 0.959 rs492943 chr10:111629030 A/T cg00817464 chr10:111662876 XPNPEP1 0.4 6.02 0.31 4.43e-9 Superior crus of antihelix expression; LIHC trans rs7246657 0.943 rs7258692 chr19:37818829 C/A cg10208301 chr11:6592745 DNHD1 0.48 6.53 0.33 2.33e-10 Coronary artery calcification; LIHC cis rs11785400 1.000 rs6997670 chr8:143737915 G/A cg10596483 chr8:143751796 JRK 0.52 8.46 0.42 7.64e-16 Schizophrenia; LIHC cis rs1862618 0.671 rs2591957 chr5:56243146 A/T cg12311346 chr5:56204834 C5orf35 0.46 6.18 0.32 1.84e-9 Initial pursuit acceleration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26011156 chr1:156183096 PMF1 0.45 6.25 0.32 1.23e-9 Pancreatic cancer; LIHC cis rs7945718 0.805 rs6486059 chr11:12824581 A/G cg25843174 chr11:12811716 TEAD1 -0.33 -7.47 -0.37 6.93e-13 Educational attainment (years of education); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20340149 chr2:122407145 CLASP1 0.41 6.17 0.32 1.9e-9 Lung function (FEV1/FVC); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg11317705 chr7:6693838 NA 0.39 6.18 0.32 1.83e-9 Calcium levels; LIHC cis rs8072100 0.967 rs2317826 chr17:45730899 C/T cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.4 -6.28 -0.32 1.05e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7091068 0.518 rs4144097 chr10:95432480 A/C cg20715218 chr10:95462985 C10orf4 0.52 7.45 0.37 7.83e-13 Urinary tract infection frequency; LIHC cis rs2617583 0.967 rs2550946 chr5:1450513 A/G cg07151155 chr5:1473589 LPCAT1 -0.41 -6.39 -0.33 5.35e-10 Breast cancer; LIHC trans rs2727020 0.718 rs1404366 chr11:49415899 T/A cg18944383 chr4:111397179 ENPEP 0.31 7.29 0.37 2.14e-12 Coronary artery disease; LIHC cis rs2668423 0.922 rs266805 chr19:1376723 C/T cg02639931 chr19:1387894 NDUFS7 -0.65 -10.24 -0.48 1.19e-21 Nonalcoholic fatty liver disease; LIHC cis rs1816752 0.870 rs7998797 chr13:25014988 A/C cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs6500602 0.634 rs2270365 chr16:4526758 G/A cg08645402 chr16:4508243 NA 0.45 8.56 0.42 3.97e-16 Schizophrenia; LIHC cis rs4660261 0.545 rs803682 chr1:44362623 G/A cg12908607 chr1:44402522 ARTN -0.48 -8.35 -0.41 1.68e-15 Intelligence (multi-trait analysis); LIHC cis rs238295 0.766 rs6085197 chr20:5511010 A/G cg24001556 chr20:5591874 RP5-1022P6.2 -0.44 -5.99 -0.31 5.36e-9 Occipital cortical area (total cortical area interaction); LIHC cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.89 0.57 2.95e-31 Alzheimer's disease; LIHC cis rs9393692 0.905 rs9393693 chr6:26277408 C/A cg13736514 chr6:26305472 NA -0.37 -6.23 -0.32 1.34e-9 Educational attainment; LIHC cis rs10911232 0.507 rs9787327 chr1:182978459 A/G ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Hypertriglyceridemia; LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.38 -0.33 5.62e-10 Menopause (age at onset); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg24474622 chr7:1103876 C7orf50 0.5 6.29 0.32 9.85e-10 Lung function (FEV1); LIHC cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg05368731 chr17:41323189 NBR1 0.73 12.58 0.56 4.54e-30 Menopause (age at onset); LIHC cis rs7264396 0.790 rs6579255 chr20:34219496 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -9.91 -0.47 1.62e-20 Total cholesterol levels; LIHC cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg25894440 chr7:65020034 NA -0.54 -6.35 -0.32 6.76e-10 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg07424592 chr7:64974309 NA 0.79 9.32 0.45 1.43e-18 Diabetic kidney disease; LIHC cis rs2979489 0.841 rs2015311 chr8:30306989 A/G cg26383811 chr8:30366931 RBPMS 0.73 12.35 0.56 3.06e-29 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs74181299 0.684 rs2302631 chr2:65331659 T/G cg05010058 chr2:65284262 CEP68 -0.4 -6.75 -0.34 6.53e-11 Pulse pressure; LIHC cis rs9814567 1.000 rs4368544 chr3:134300014 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.25 0.55 7.28e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs881375 0.967 rs2109895 chr9:123677827 C/T cg14580859 chr9:123691850 NA 0.37 6.55 0.33 2.11e-10 Rheumatoid arthritis; LIHC cis rs151997 0.962 rs27612 chr5:50179120 G/A cg06027927 chr5:50259733 NA 0.57 7.61 0.38 2.61e-13 Callous-unemotional behaviour; LIHC cis rs12458462 0.892 rs35928863 chr18:77438956 A/G cg11879182 chr18:77439856 CTDP1 0.85 14.72 0.62 2.4e-38 Monocyte count; LIHC cis rs6867032 1.000 rs4413568 chr5:2016894 A/G cg26168224 chr5:2018326 NA 0.29 6.94 0.35 1.93e-11 Gut microbiome composition (winter); LIHC cis rs6598955 0.543 rs6699798 chr1:26556442 G/T cg04990556 chr1:26633338 UBXN11 0.75 10.68 0.5 3.6e-23 Obesity-related traits; LIHC cis rs7044106 0.762 rs13291660 chr9:123392748 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 7.23 0.36 3.09e-12 Hip circumference adjusted for BMI; LIHC cis rs9611565 0.649 rs5758434 chr22:42116163 G/A cg06634786 chr22:41940651 POLR3H 0.56 6.08 0.31 3.22e-9 Vitiligo; LIHC cis rs11971779 0.680 rs12154842 chr7:139078484 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22197824 chr11:65431114 RELA 0.45 6.17 0.32 1.96e-9 Lung function (FEV1/FVC); LIHC cis rs116095464 0.558 rs62347677 chr5:227453 A/G cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg02951883 chr7:2050386 MAD1L1 -0.59 -9.09 -0.44 8.46e-18 Bipolar disorder and schizophrenia; LIHC trans rs11039798 0.623 rs7294273 chr11:48705374 T/C cg03929089 chr4:120376271 NA 0.53 6.13 0.31 2.36e-9 Axial length; LIHC trans rs1421898 0.509 rs62385378 chr5:158327312 G/A cg10462998 chr5:175976188 PCDH24 -0.71 -6.08 -0.31 3.22e-9 Inflammatory skin disease; LIHC trans rs1814175 0.647 rs61306292 chr11:49856040 G/C cg03929089 chr4:120376271 NA -0.9 -18.38 -0.7 5.63e-53 Height; LIHC cis rs7945718 0.591 rs7937898 chr11:12703561 G/T cg25843174 chr11:12811716 TEAD1 -0.32 -7.27 -0.37 2.39e-12 Educational attainment (years of education); LIHC cis rs904251 0.504 rs2797795 chr6:37480683 T/C cg08126542 chr6:37504118 NA -0.37 -6.37 -0.33 5.94e-10 Cognitive performance; LIHC cis rs4927850 1.000 rs7625570 chr3:195747398 A/G cg01181863 chr3:195395398 SDHAP2 -0.53 -6.98 -0.35 1.58e-11 Pancreatic cancer; LIHC cis rs9905704 0.647 rs6503888 chr17:57028126 T/C cg12560992 chr17:57184187 TRIM37 0.68 9.92 0.47 1.53e-20 Testicular germ cell tumor; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03277652 chr8:142011117 PTK2 0.39 6.23 0.32 1.36e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs1843834 0.929 rs4674934 chr2:225516468 A/T cg22509189 chr2:225307070 NA 0.54 7.13 0.36 5.82e-12 IgE levels in asthmatics (D.p. specific); LIHC cis rs763121 0.744 rs5757140 chr22:38957013 T/C cg14440974 chr22:39074834 NA -0.44 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC cis rs9534288 0.797 rs7331069 chr13:46564609 A/T cg15192986 chr13:46630673 CPB2 0.47 7.12 0.36 6.44e-12 Blood protein levels; LIHC cis rs7197653 0.748 rs58542611 chr16:68350219 C/T cg05110241 chr16:68378359 PRMT7 -0.9 -9.88 -0.47 2.02e-20 Magnesium levels; LIHC cis rs8103278 0.507 rs16939 chr19:46276056 C/A cg11657440 chr19:46296263 DMWD 0.68 12.7 0.57 1.57e-30 Coronary artery disease; LIHC cis rs757110 0.770 rs2051772 chr11:17389850 G/A cg15432903 chr11:17409602 KCNJ11 0.65 10.12 0.48 3.11e-21 Type 2 diabetes; LIHC cis rs3008870 0.959 rs2985810 chr1:67376162 T/C cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.29e-8 Lymphocyte percentage of white cells; LIHC cis rs7945718 0.621 rs12281511 chr11:12677295 A/C cg25843174 chr11:12811716 TEAD1 0.33 7.71 0.38 1.42e-13 Educational attainment (years of education); LIHC cis rs1355223 1.000 rs1396883 chr11:34757447 C/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.2 -0.32 1.62e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6062509 0.965 rs4809330 chr20:62349586 A/G cg03999872 chr20:62272968 STMN3 0.4 6.07 0.31 3.41e-9 Prostate cancer; LIHC cis rs1008375 1.000 rs2058338 chr4:17678600 A/G cg02297831 chr4:17616191 MED28 -0.46 -7.43 -0.37 8.85e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12586317 0.545 rs58342373 chr14:35395269 T/C cg05294307 chr14:35346193 BAZ1A -0.43 -6.38 -0.33 5.83e-10 Psoriasis; LIHC cis rs1577917 0.561 rs3087978 chr6:86388223 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.5 0.33 2.88e-10 Response to antipsychotic treatment; LIHC cis rs1008375 1.000 rs1558377 chr4:17650758 A/G cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs7613875 0.580 rs2624819 chr3:50010571 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.42 6.5 0.33 2.86e-10 Body mass index; LIHC cis rs9768139 0.733 rs56205111 chr7:158121055 T/C cg06219351 chr7:158114137 PTPRN2 -0.21 -6.02 -0.31 4.53e-9 Calcium levels; LIHC cis rs2839186 0.872 rs13052233 chr21:47707284 G/T cg05896524 chr21:47604654 C21orf56 0.44 6.62 0.34 1.38e-10 Testicular germ cell tumor; LIHC cis rs748404 0.578 rs2012467 chr15:43690565 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.55 8.69 0.43 1.48e-16 Lung cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20676401 chr10:5726466 C10orf18 -0.46 -6.53 -0.33 2.41e-10 Pancreatic cancer; LIHC cis rs1865760 1.000 rs2071297 chr6:25924513 C/G cg17691542 chr6:26056736 HIST1H1C -0.4 -6.06 -0.31 3.56e-9 Height; LIHC cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.86 -0.3 1.11e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs514406 0.679 rs960570 chr1:53237763 A/G cg24675658 chr1:53192096 ZYG11B 0.83 13.58 0.59 6.5e-34 Monocyte count; LIHC cis rs2230307 0.572 rs512999 chr1:100563330 A/G cg24955406 chr1:100503596 HIAT1 0.61 6.06 0.31 3.51e-9 Carotid intima media thickness; LIHC cis rs2236918 1.000 rs2995544 chr1:242020495 C/T cg17736920 chr1:242011382 EXO1 0.59 8.65 0.42 2.05e-16 Menopause (age at onset); LIHC cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg25072359 chr17:41440525 NA 0.37 5.83 0.3 1.3e-8 Menopause (age at onset); LIHC cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg20607798 chr8:58055168 NA 0.67 7.83 0.39 6.21e-14 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.753 rs1637051 chr7:75730659 G/A cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.37e-16 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs7777677 0.925 rs4726547 chr7:142370582 C/T cg21680980 chr1:221069572 NA -0.48 -6.08 -0.31 3.27e-9 Alcoholic chronic pancreatitis; LIHC cis rs9303401 1.000 rs6503882 chr17:56915761 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.45 6.63 0.34 1.29e-10 Cognitive test performance; LIHC cis rs6066825 0.644 rs6095248 chr20:47320932 A/G cg18078177 chr20:47281410 PREX1 0.42 6.97 0.35 1.65e-11 Colorectal cancer; LIHC cis rs2637266 0.783 rs2395436 chr10:78488513 G/T cg18941641 chr10:78392320 NA 0.27 5.81 0.3 1.42e-8 Pulmonary function; LIHC cis rs6545883 0.965 rs3771261 chr2:61762161 A/G cg14146966 chr2:61757674 XPO1 0.48 8.45 0.42 8.6e-16 Tuberculosis; LIHC cis rs7408868 0.706 rs7257550 chr19:15292088 C/G cg14696996 chr19:15285081 NOTCH3 0.46 6.25 0.32 1.23e-9 Pulse pressure; LIHC cis rs7602441 0.521 rs8849 chr2:14780131 A/G cg06545361 chr2:14773388 FAM84A 0.55 6.29 0.32 9.56e-10 Visceral adipose tissue adjusted for BMI; LIHC cis rs10463316 0.894 rs10476769 chr5:150763970 A/G cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.05e-10 Metabolite levels (Pyroglutamine); LIHC cis rs12602486 1.000 rs76971031 chr17:42242724 T/G cg13607699 chr17:42295918 UBTF -0.75 -6.42 -0.33 4.46e-10 Glycated hemoglobin levels; LIHC trans rs941408 1.000 rs1736180 chr19:2796021 C/T cg19676328 chr12:49525230 TUBA1B -0.37 -6.09 -0.31 3e-9 Total cholesterol levels; LIHC cis rs2236918 1.000 rs1776137 chr1:242027045 A/G cg17736920 chr1:242011382 EXO1 0.62 8.92 0.43 2.88e-17 Menopause (age at onset); LIHC cis rs7639513 0.545 rs13061104 chr3:12717321 G/T cg23032965 chr3:12705835 RAF1 0.58 6.38 0.33 5.85e-10 Itch intensity from mosquito bite; LIHC cis rs28489187 0.683 rs11161607 chr1:85855855 T/C cg16011679 chr1:85725395 C1orf52 0.46 5.82 0.3 1.36e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs2404602 0.552 rs11634428 chr15:77084582 T/C cg23625390 chr15:77176239 SCAPER -0.46 -7.31 -0.37 1.89e-12 Blood metabolite levels; LIHC cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg06453172 chr10:134556979 INPP5A -0.64 -8.01 -0.4 1.81e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs11039798 0.623 rs588700 chr11:48449889 T/C cg15704280 chr7:45808275 SEPT13 -0.58 -6.43 -0.33 4.29e-10 Axial length; LIHC trans rs11039798 0.777 rs2202454 chr11:49011009 T/C cg15704280 chr7:45808275 SEPT13 0.61 6.36 0.33 6.55e-10 Axial length; LIHC cis rs3736485 0.966 rs11636170 chr15:51767087 G/T cg08986416 chr15:51914746 DMXL2 -0.4 -5.95 -0.31 6.79e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg09417038 chr21:47716443 C21orf57 0.5 7.65 0.38 2.04e-13 Testicular germ cell tumor; LIHC cis rs138880 0.542 rs9616371 chr22:50306338 G/A cg02269571 chr22:50332266 NA -1.03 -10.62 -0.5 6.05e-23 Schizophrenia; LIHC cis rs4665809 1.000 rs4233708 chr2:26291345 C/T cg27170947 chr2:26402098 FAM59B -0.65 -7.98 -0.4 2.22e-14 Gut microbiome composition (summer); LIHC cis rs2075671 0.855 rs62483567 chr7:100286435 G/A cg20848291 chr7:100343083 ZAN -0.46 -6.55 -0.33 2.1e-10 Other erythrocyte phenotypes; LIHC cis rs1801251 0.778 rs778338 chr2:233740227 A/G cg25237894 chr2:233734115 C2orf82 -0.6 -11.82 -0.54 2.81e-27 Coronary artery disease; LIHC trans rs6952808 0.723 rs4721295 chr7:2036669 G/T cg04565464 chr8:145669602 NFKBIL2 -0.4 -6.69 -0.34 8.99e-11 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04127825 chr1:167503222 NA 0.49 7.04 0.36 1.08e-11 Pancreatic cancer; LIHC cis rs9303401 0.614 rs34900851 chr17:56566399 G/A cg25039879 chr17:56429692 SUPT4H1 0.75 8.41 0.41 1.1e-15 Cognitive test performance; LIHC cis rs3789045 0.774 rs898388 chr1:204500257 C/T cg17419461 chr1:204415978 PIK3C2B -0.4 -6.26 -0.32 1.13e-9 Educational attainment (college completion); LIHC trans rs1814175 0.817 rs7481230 chr11:49772235 G/A cg18944383 chr4:111397179 ENPEP 0.28 7.08 0.36 8.31e-12 Height; LIHC trans rs12960119 0.536 rs12968175 chr18:23716392 A/G cg05333146 chr16:67183725 B3GNT9 0.64 6.06 0.31 3.57e-9 Rhegmatogenous retinal detachment; LIHC cis rs1707322 0.686 rs1084086 chr1:46041100 A/C cg06784218 chr1:46089804 CCDC17 -0.4 -7.06 -0.36 9.32e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10752881 1.000 rs10752887 chr1:182990834 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.41 0.49 3.07e-22 Colorectal cancer; LIHC cis rs11190604 0.943 rs3750631 chr10:102279294 A/G cg07080220 chr10:102295463 HIF1AN 0.57 8.26 0.41 3.32e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -10.49 -0.49 1.7e-22 Platelet count; LIHC cis rs2075371 0.611 rs62462979 chr7:134019379 G/T cg20476274 chr7:133979776 SLC35B4 0.5 6.86 0.35 3.24e-11 Mean platelet volume; LIHC cis rs9309711 0.737 rs9284795 chr2:3492065 G/A cg10845886 chr2:3471009 TTC15 -0.57 -10.24 -0.48 1.18e-21 Neurofibrillary tangles; LIHC cis rs9916302 0.861 rs10491129 chr17:37461643 T/G cg00129232 chr17:37814104 STARD3 0.39 6.32 0.32 8.29e-10 Glomerular filtration rate (creatinine); LIHC cis rs10170846 0.893 rs10932967 chr2:223544111 C/T cg25565276 chr2:223520875 FARSB 0.62 9.27 0.45 2.19e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs6754311 0.550 rs10173394 chr2:136522675 C/T cg17750252 chr2:136567154 LCT 0.35 6.11 0.31 2.68e-9 Mosquito bite size; LIHC cis rs35110281 0.659 rs11909064 chr21:45092095 G/C cg21573476 chr21:45109991 RRP1B -0.6 -11.47 -0.53 5.39e-26 Mean corpuscular volume; LIHC cis rs4845570 1.000 rs6673002 chr1:151743275 G/T cg07092448 chr1:151763213 TDRKH 0.67 7.56 0.38 3.69e-13 Coronary artery disease; LIHC cis rs17685 0.775 rs11761172 chr7:75761547 C/T cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1707322 0.716 rs6699444 chr1:46135120 G/C cg03146154 chr1:46216737 IPP 0.57 9.74 0.47 5.94e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1997103 0.765 rs55686950 chr7:55396552 A/C cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7267979 1.000 rs2258884 chr20:25279539 C/T cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg11060661 chr22:24314208 DDT;DDTL 0.6 9.85 0.47 2.53e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs62103177 0.673 rs4438371 chr18:77615988 C/T cg05926928 chr17:57297772 GDPD1 0.57 7.66 0.38 1.94e-13 Opioid sensitivity; LIHC cis rs7131987 0.650 rs67146951 chr12:29450553 C/A cg05697976 chr12:29376483 FAR2 0.3 6.17 0.32 1.9e-9 QT interval; LIHC cis rs11229555 1.000 rs12808544 chr11:58373221 C/A cg15696309 chr11:58395628 NA -0.73 -8.95 -0.44 2.24e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg13903917 chr12:124904514 NCOR2 0.35 6.14 0.32 2.25e-9 Oropharynx cancer; LIHC cis rs7959452 0.640 rs1598543 chr12:69688757 G/T cg20891283 chr12:69753455 YEATS4 0.81 15.37 0.64 6.44e-41 Blood protein levels; LIHC cis rs1355223 0.872 rs1258466 chr11:34730066 T/A cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.32 -0.32 8.28e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2274273 0.870 rs4597235 chr14:55851987 A/G cg01864836 chr14:55583639 NA -0.41 -7.67 -0.38 1.79e-13 Protein biomarker; LIHC trans rs2797160 0.651 rs1269176 chr6:126029682 A/T cg05039488 chr6:79577232 IRAK1BP1 -0.56 -8.49 -0.42 6.3e-16 Endometrial cancer; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg06873352 chr17:61820015 STRADA 0.74 13.21 0.58 1.74e-32 Prudent dietary pattern; LIHC cis rs2980439 0.556 rs2921059 chr8:8317887 G/T cg15556689 chr8:8085844 FLJ10661 0.55 8.66 0.42 1.92e-16 Neuroticism; LIHC cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.53e-9 Menopause (age at onset); LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs11031096 0.563 rs12289940 chr11:4224589 T/A cg18678763 chr11:4115507 RRM1 -0.43 -6.45 -0.33 3.87e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg02993280 chr1:107599747 PRMT6 0.58 9.27 0.45 2.16e-18 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs11760633 0.607 rs11760284 chr7:1827569 C/T cg00395210 chr12:48592465 NA 0.34 6.06 0.31 3.5e-9 Coronary artery disease; LIHC cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg19729930 chr2:74357872 NA 0.84 18.33 0.7 9.26e-53 Gestational age at birth (maternal effect); LIHC cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg09222892 chr1:25734099 RHCE -0.46 -8.24 -0.41 3.62e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs8044995 0.501 rs73613952 chr16:68352808 G/C cg05110241 chr16:68378359 PRMT7 -0.9 -10.01 -0.48 7.42e-21 Schizophrenia; LIHC cis rs3806843 0.900 rs2531341 chr5:140130894 C/T cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2599510 0.703 rs58852184 chr2:32729763 A/T cg02381751 chr2:32503542 YIPF4 0.45 5.88 0.3 9.98e-9 Interleukin-18 levels; LIHC cis rs13256369 0.708 rs10903310 chr8:8589687 A/C cg18904891 chr8:8559673 CLDN23 -0.63 -9.92 -0.47 1.45e-20 Obesity-related traits; LIHC cis rs2197308 0.740 rs11182251 chr12:37919611 C/T cg26384229 chr12:38710491 ALG10B -0.48 -6.7 -0.34 8.5e-11 Morning vs. evening chronotype; LIHC cis rs7216064 1.000 rs62084251 chr17:65878736 G/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2176862 1.000 rs2280414 chr3:46621215 T/C cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.3 -0.32 9.3e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs1865760 0.929 rs1816546 chr6:25938252 C/T cg03517284 chr6:25882590 NA -0.44 -6.65 -0.34 1.17e-10 Height; LIHC cis rs2842992 0.830 rs2842974 chr6:160159034 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.93 0.54 1.12e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs7918232 0.941 rs6482598 chr10:27426375 T/C cg14442939 chr10:27389572 ANKRD26 0.72 7.07 0.36 8.65e-12 Breast cancer; LIHC cis rs1499280 0.920 rs1157137 chr5:52099093 G/T cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs11098499 0.866 rs6857892 chr4:120282696 G/T cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs4555082 0.834 rs2735826 chr14:105710866 G/A cg10792982 chr14:105748885 BRF1 0.48 6.3 0.32 9.36e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs11252926 0.507 rs4881199 chr10:428090 C/G cg16346588 chr10:242978 ZMYND11 0.42 6.34 0.32 7.35e-10 Psychosis in Alzheimer's disease; LIHC cis rs4742903 0.967 rs10512325 chr9:106861191 C/T cg14250997 chr9:106856677 SMC2 0.42 7.45 0.37 7.54e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs826838 0.904 rs1554550 chr12:39208889 G/A cg26384229 chr12:38710491 ALG10B 0.77 9.41 0.45 7.37e-19 Heart rate; LIHC cis rs2760061 0.603 rs697761 chr1:228192397 G/A cg02753203 chr1:228287806 NA 0.72 10.35 0.49 5.28e-22 Diastolic blood pressure; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC cis rs1816752 0.870 rs2033955 chr13:25010544 T/C cg22771759 chr13:24902376 NA 0.32 6.7 0.34 8.43e-11 Obesity-related traits; LIHC cis rs6912958 0.559 rs242267 chr6:88061837 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.71 -13.43 -0.59 2.45e-33 Monocyte percentage of white cells; LIHC cis rs79387448 0.745 rs72995658 chr2:103176773 A/G cg09003973 chr2:102972529 NA 0.87 7.47 0.37 6.66e-13 Gut microbiota (bacterial taxa); LIHC cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg02503808 chr4:7069936 GRPEL1 0.76 11.43 0.53 7.6e-26 Monocyte percentage of white cells; LIHC cis rs13191362 0.935 rs13193473 chr6:162966852 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.71 6.03 0.31 4.22e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7208859 0.623 rs9890558 chr17:29110355 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs769267 0.965 rs8101938 chr19:19390497 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC cis rs6089829 0.855 rs6062781 chr20:61667128 G/A cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16517634 chr2:8977876 KIDINS220 0.42 6.08 0.31 3.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg02290350 chr8:58132656 NA 0.47 8.61 0.42 2.81e-16 Developmental language disorder (linguistic errors); LIHC cis rs61990749 0.597 rs176943 chr14:78175797 T/G cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.79 0.39 8.09e-14 Fibroblast growth factor basic levels; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg11060661 chr22:24314208 DDT;DDTL 0.62 10.94 0.51 4.41e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs903552 1.000 rs8043205 chr15:102005749 A/G cg25677261 chr15:102009856 PCSK6 -0.46 -6.22 -0.32 1.44e-9 Diabetic kidney disease; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/T cg03715129 chr7:2117724 MAD1L1 -0.77 -5.82 -0.3 1.36e-8 Bipolar disorder and schizophrenia; LIHC cis rs2629751 0.512 rs2722169 chr12:104415450 C/T cg14987745 chr12:104360022 TDG -0.69 -6.84 -0.35 3.56e-11 Hepatitis C induced liver fibrosis; LIHC cis rs2607426 1.000 rs2249854 chr19:41269481 T/C cg20631044 chr19:41255890 C19orf54;SNRPA -0.48 -5.82 -0.3 1.36e-8 Blood protein levels; LIHC trans rs4342066 0.736 rs1599951 chr3:28359788 G/A cg11103623 chr3:57235255 HESX1 0.38 6.2 0.32 1.65e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1461503 0.900 rs7119398 chr11:122832492 C/A cg25161029 chr11:122845972 NA 0.4 6.7 0.34 8.39e-11 Menarche (age at onset); LIHC cis rs8077889 0.917 rs72836559 chr17:41913529 C/T cg26893861 chr17:41843967 DUSP3 0.99 10.76 0.5 1.9e-23 Triglycerides; LIHC cis rs17376456 0.825 rs12153021 chr5:93073913 A/G cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs12477438 0.539 rs720228 chr2:99704547 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.39 0.61 4.74e-37 Chronic sinus infection; LIHC cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg00750074 chr16:89608354 SPG7 -0.48 -7.84 -0.39 5.63e-14 Multiple myeloma (IgH translocation); LIHC cis rs7903847 0.544 rs61861865 chr10:99144867 C/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2839186 0.560 rs9975345 chr21:47843004 T/C cg12379764 chr21:47803548 PCNT 0.64 9.96 0.47 1.13e-20 Testicular germ cell tumor; LIHC cis rs7666738 0.519 rs13136069 chr4:98819568 C/T cg05340658 chr4:99064831 C4orf37 0.49 6.46 0.33 3.65e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg08499158 chr17:42289980 UBTF -0.52 -8.55 -0.42 4.12e-16 Total body bone mineral density; LIHC cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg07061783 chr6:25882402 NA -0.53 -6.44 -0.33 3.95e-10 Intelligence (multi-trait analysis); LIHC trans rs9929218 1.000 rs7200690 chr16:68778457 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -9.23 -0.45 2.96e-18 Colorectal cancer; LIHC cis rs9818758 0.607 rs3923475 chr3:49055788 G/T cg00383909 chr3:49044727 WDR6 0.85 7.04 0.36 1.09e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs644799 0.687 rs3748252 chr11:95519195 A/T cg03916912 chr11:95522834 CEP57;FAM76B -0.72 -11.97 -0.54 8.1e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC trans rs2832191 0.716 rs7284006 chr21:30475186 T/A cg14791747 chr16:20752902 THUMPD1 -0.46 -6.49 -0.33 3.01e-10 Dental caries; LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg18658371 chr14:91527208 RPS6KA5 -0.83 -6.3 -0.32 9.32e-10 Mild influenza (H1N1) infection; LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg00656387 chr3:40428638 ENTPD3 -0.51 -8.73 -0.43 1.15e-16 Renal cell carcinoma; LIHC cis rs12477438 0.520 rs34766932 chr2:99737273 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.88 15.61 0.65 7.25e-42 Chronic sinus infection; LIHC cis rs1163251 0.902 rs639761 chr1:120217558 G/A cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC cis rs7772486 0.686 rs1415744 chr6:146022531 C/T cg13319975 chr6:146136371 FBXO30 -0.36 -5.98 -0.31 5.64e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1005277 0.579 rs176838 chr10:38371899 A/T cg25427524 chr10:38739819 LOC399744 0.64 12.25 0.55 7.35e-29 Extrinsic epigenetic age acceleration; LIHC cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.46 6.55 0.33 2.07e-10 Schizophrenia; LIHC cis rs3736485 0.808 rs28576876 chr15:51951252 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -5.85 -0.3 1.18e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7119 0.717 rs8032071 chr15:77745762 C/T cg17802220 chr15:77601643 NA 0.39 6.56 0.33 1.97e-10 Type 2 diabetes; LIHC trans rs7618501 1.000 rs695238 chr3:49869158 A/C cg21659725 chr3:3221576 CRBN 0.97 19.09 0.72 8.38e-56 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg06481639 chr22:41940642 POLR3H -0.7 -7.09 -0.36 7.55e-12 Vitiligo; LIHC cis rs644799 0.965 rs2950522 chr11:95524719 C/T cg25478527 chr11:95522999 CEP57;FAM76B 0.43 5.96 0.31 6.26e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7100689 0.754 rs10736339 chr10:82059970 G/C cg00277334 chr10:82204260 NA -0.55 -6.91 -0.35 2.43e-11 Post bronchodilator FEV1; LIHC cis rs651907 0.737 rs9844218 chr3:101584983 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.45 -6.05 -0.31 3.85e-9 Colorectal cancer; LIHC cis rs7927771 0.524 rs10838732 chr11:47607940 C/G cg20307385 chr11:47447363 PSMC3 0.8 12.14 0.55 1.92e-28 Subjective well-being; LIHC cis rs11098499 0.908 rs1002152 chr4:120273387 C/A cg09307838 chr4:120376055 NA 0.75 11.62 0.53 1.58e-26 Corneal astigmatism; LIHC cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg10360323 chr17:41437877 NA 0.39 5.84 0.3 1.22e-8 Menopause (age at onset); LIHC cis rs6121246 0.909 rs4518038 chr20:30419051 A/G cg13852791 chr20:30311386 BCL2L1 0.84 8.1 0.4 9.65e-15 Mean corpuscular hemoglobin; LIHC cis rs6138458 1.000 rs227658 chr20:24932028 A/G cg26195577 chr20:24973756 C20orf3 1.17 15.21 0.64 2.92e-40 Blood protein levels; LIHC cis rs929354 0.739 rs1182439 chr7:157027367 G/A cg17757837 chr7:157058334 UBE3C -0.72 -11.77 -0.54 4.33e-27 Body mass index; LIHC cis rs12824058 0.831 rs4759658 chr12:130815872 C/T cg26677194 chr12:130822605 PIWIL1 0.51 7.17 0.36 4.52e-12 Menopause (age at onset); LIHC cis rs722599 0.683 rs7160852 chr14:75239424 T/C cg11812906 chr14:75593930 NEK9 0.44 6.64 0.34 1.22e-10 IgG glycosylation; LIHC cis rs4819052 0.819 rs34818688 chr21:46672416 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 10.93 0.51 4.75e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3736485 0.932 rs2899477 chr15:51937701 C/T cg08986416 chr15:51914746 DMXL2 -0.43 -6.12 -0.31 2.5e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7408868 1.000 rs10406754 chr19:15274201 T/A cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC cis rs2228479 0.850 rs62052711 chr16:89855100 C/A cg06558623 chr16:89946397 TCF25 0.84 10.93 0.51 4.91e-24 Skin colour saturation; LIHC cis rs1865760 0.566 rs3752420 chr6:26027135 G/A cg18357526 chr6:26021779 HIST1H4A 0.46 6.83 0.35 3.96e-11 Height; LIHC cis rs2576037 0.526 rs4890707 chr18:44497724 C/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.47 -6.99 -0.35 1.49e-11 Personality dimensions; LIHC cis rs908922 0.676 rs526099 chr1:152497811 T/C cg20991723 chr1:152506922 NA 0.59 10.51 0.49 1.45e-22 Hair morphology; LIHC cis rs9581857 0.615 rs3759435 chr13:27996813 T/G cg22138327 chr13:27999177 GTF3A 0.54 7.85 0.39 5.45e-14 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs9768139 0.708 rs36064654 chr7:158116632 C/T cg25566285 chr7:158114605 PTPRN2 0.23 6.21 0.32 1.5e-9 Calcium levels; LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg24209194 chr3:40518798 ZNF619 0.63 9.65 0.46 1.17e-19 Renal cell carcinoma; LIHC cis rs61990749 0.597 rs1978416 chr14:78227901 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.62 10.29 0.49 8.26e-22 Fibroblast growth factor basic levels; LIHC cis rs57221529 0.713 rs72703072 chr5:590626 A/G cg09021430 chr5:549028 NA -0.43 -8.53 -0.42 4.8e-16 Lung disease severity in cystic fibrosis; LIHC cis rs2576037 0.526 rs2010834 chr18:44560875 C/A cg19077165 chr18:44547161 KATNAL2 0.43 6.49 0.33 3.09e-10 Personality dimensions; LIHC cis rs7312933 0.558 rs11181463 chr12:42763636 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.56 8.32 0.41 2.19e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg10896456 chr17:42255109 ASB16;C17orf65 0.43 7.7 0.38 1.51e-13 Total body bone mineral density; LIHC cis rs57244997 0.725 rs61574422 chr6:162425056 T/C cg17173639 chr6:162384350 PARK2 -0.56 -7.09 -0.36 7.55e-12 Mosquito bite size; LIHC cis rs11098499 0.739 rs9996382 chr4:120151012 C/T cg09307838 chr4:120376055 NA 0.5 7.68 0.38 1.67e-13 Corneal astigmatism; LIHC cis rs17253792 0.822 rs17685078 chr14:56127202 T/C cg01858014 chr14:56050164 KTN1 -0.71 -7.22 -0.36 3.38e-12 Putamen volume; LIHC cis rs2153535 0.580 rs1832101 chr6:8460177 A/G cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.28e-27 Motion sickness; LIHC cis rs12699477 0.545 rs117125814 chr7:1910681 T/G cg20295408 chr7:1910781 MAD1L1 -0.46 -6.59 -0.34 1.7e-10 Testicular germ cell tumor; LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.76 0.78 1.78e-70 Height; LIHC cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg25364880 chr3:44379878 C3orf23 0.54 7.35 0.37 1.48e-12 Depressive symptoms; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10620100 chr15:40714174 NA 0.43 6.13 0.31 2.36e-9 Pancreatic cancer; LIHC cis rs11023332 0.650 rs2122942 chr11:14807375 T/G cg19336497 chr11:14380999 RRAS2 -0.35 -6.18 -0.32 1.78e-9 Adiponectin levels;Vitamin D levels; LIHC trans rs1814175 0.533 rs4528310 chr11:49983106 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs7772486 0.754 rs702323 chr6:146008274 A/G cg23711669 chr6:146136114 FBXO30 -0.6 -10.0 -0.48 8.01e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.646 rs61904497 chr11:49883449 A/T cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.43e-11 Height; LIHC trans rs859980 0.514 rs9386402 chr6:104519786 C/T cg11635524 chr19:46850777 PPP5C -0.45 -6.31 -0.32 8.44e-10 Tourette's syndrome or obsessive-compulsive disorder; LIHC cis rs9394841 0.667 rs3827633 chr6:41759846 A/C cg08135965 chr6:41755394 TOMM6 0.44 5.72 0.3 2.34e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg20818283 chr2:191399100 TMEM194B 0.46 6.16 0.32 2.1e-9 Pulse pressure; LIHC cis rs10792665 0.640 rs1904426 chr11:82620122 G/C cg24227371 chr11:82718527 RAB30 -0.27 -6.13 -0.31 2.41e-9 Obesity-related traits; LIHC cis rs4474465 0.790 rs7106931 chr11:78229612 A/G cg02023728 chr11:77925099 USP35 -0.35 -6.17 -0.32 1.92e-9 Alzheimer's disease (survival time); LIHC cis rs6701037 0.681 rs13374887 chr1:175131962 A/T cg00958927 chr1:175162553 KIAA0040 0.39 6.37 0.33 5.98e-10 Alcohol dependence; LIHC cis rs7520050 0.843 rs1707334 chr1:46605728 A/C cg23431851 chr1:46668822 C1orf190;POMGNT1 0.38 5.8 0.3 1.5e-8 Red blood cell count;Reticulocyte count; LIHC cis rs4908768 0.579 rs55840223 chr1:8862787 G/C cg20416874 chr1:8611966 RERE 0.4 5.77 0.3 1.75e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs11098499 0.863 rs6534141 chr4:120485223 A/T cg09307838 chr4:120376055 NA 0.74 11.27 0.52 3e-25 Corneal astigmatism; LIHC cis rs7617480 0.648 rs7653408 chr3:48972351 A/C cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.37 0.33 6.27e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs4759375 1.000 rs11057224 chr12:123755179 A/G cg00376283 chr12:123451042 ABCB9 -0.5 -6.24 -0.32 1.27e-9 HDL cholesterol; LIHC cis rs12497850 0.931 rs9682444 chr3:48852639 A/G cg07636037 chr3:49044803 WDR6 0.93 16.69 0.67 3.76e-46 Parkinson's disease; LIHC cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg06481639 chr22:41940642 POLR3H -0.7 -7.16 -0.36 5.06e-12 Vitiligo; LIHC cis rs372883 0.648 rs1153292 chr21:30689195 G/T cg24692254 chr21:30365293 RNF160 -0.52 -6.63 -0.34 1.33e-10 Pancreatic cancer; LIHC cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg20011983 chr2:74347215 NA -0.43 -6.28 -0.32 1.01e-9 Gestational age at birth (maternal effect); LIHC cis rs3812831 0.695 rs913526 chr13:114928946 G/C cg08824895 chr13:115047677 UPF3A 0.48 6.74 0.34 6.74e-11 Schizophrenia; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.67 0.57 2.05e-30 Prudent dietary pattern; LIHC cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg20887711 chr4:1340912 KIAA1530 -0.76 -11.82 -0.54 3e-27 Longevity; LIHC cis rs7100689 0.784 rs1972370 chr10:82127180 A/G cg01528321 chr10:82214614 TSPAN14 0.87 11.84 0.54 2.43e-27 Post bronchodilator FEV1; LIHC cis rs727505 0.865 rs10253613 chr7:124508929 G/A cg23710748 chr7:124431027 NA -0.32 -5.78 -0.3 1.66e-8 Lewy body disease; LIHC cis rs9378688 1.000 rs9392374 chr6:2223002 T/G cg12303981 chr6:2244766 GMDS -0.49 -6.22 -0.32 1.48e-9 Caudate nucleus volume; LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.645 rs1851844 chr11:50021773 T/C cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs1882538 0.569 rs11562037 chr7:133076885 A/G cg10665199 chr7:133106180 EXOC4 0.49 8.09 0.4 1.03e-14 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg20607798 chr8:58055168 NA 0.58 6.42 0.33 4.46e-10 Developmental language disorder (linguistic errors); LIHC cis rs10411936 0.750 rs8112401 chr19:16593012 C/T cg10248733 chr19:16607483 C19orf44;CALR3 0.48 6.41 0.33 4.8e-10 White blood cell count;Multiple sclerosis; LIHC cis rs3008870 0.583 rs11208978 chr1:67442210 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.87 -13.34 -0.59 5.45e-33 Lymphocyte percentage of white cells; LIHC cis rs7927771 0.832 rs10769258 chr11:47391039 C/T cg20307385 chr11:47447363 PSMC3 0.45 6.07 0.31 3.4e-9 Subjective well-being; LIHC trans rs916888 0.773 rs199443 chr17:44819565 C/T cg07870213 chr5:140052090 DND1 1.02 10.59 0.5 7.69e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg12310025 chr6:25882481 NA -0.69 -8.87 -0.43 4.17e-17 Intelligence (multi-trait analysis); LIHC cis rs9905704 0.647 rs9901655 chr17:56987142 G/A cg12560992 chr17:57184187 TRIM37 0.69 10.0 0.48 7.85e-21 Testicular germ cell tumor; LIHC cis rs963731 0.649 rs2924710 chr2:39302757 G/C cg04010122 chr2:39346883 SOS1 -0.7 -6.32 -0.32 8.07e-10 Corticobasal degeneration; LIHC cis rs7959452 0.535 rs2305641 chr12:69646914 C/T cg14784868 chr12:69753453 YEATS4 0.82 15.31 0.64 1.17e-40 Blood protein levels; LIHC cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC trans rs6073597 0.967 rs2284276 chr20:43682124 C/T cg14213297 chr9:130870109 SLC25A25 0.34 6.08 0.31 3.19e-9 Positive affect; LIHC cis rs11673344 0.764 rs547483 chr19:37441365 C/T cg27390819 chr19:37464633 NA 0.53 6.47 0.33 3.34e-10 Obesity-related traits; LIHC cis rs9911578 1.000 rs2531729 chr17:56539890 C/T cg05425664 chr17:57184151 TRIM37 -0.57 -8.5 -0.42 5.79e-16 Intelligence (multi-trait analysis); LIHC cis rs6456156 0.586 rs7742305 chr6:167485723 C/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.51 -0.42 5.66e-16 Primary biliary cholangitis; LIHC cis rs7258465 1.000 rs7251653 chr19:18608283 C/T cg10790698 chr19:18539756 SSBP4 -0.36 -7.53 -0.38 4.6e-13 Breast cancer; LIHC cis rs748404 0.723 rs11853991 chr15:43557549 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 6.36 0.33 6.31e-10 Lung cancer; LIHC cis rs7106204 0.514 rs7123539 chr11:24272000 G/A ch.11.24196551F chr11:24239977 NA -0.73 -8.88 -0.43 3.8e-17 Response to Homoharringtonine (cytotoxicity); LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg07157834 chr1:205819609 PM20D1 0.66 9.79 0.47 4.08e-20 Menarche (age at onset); LIHC cis rs1348850 1.000 rs3927978 chr2:178443854 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.75 -11.37 -0.52 1.26e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4718428 0.705 rs13231140 chr7:66361618 C/G cg18252515 chr7:66147081 NA -0.68 -9.28 -0.45 1.97e-18 Corneal structure; LIHC cis rs7319311 0.748 rs9515198 chr13:111029065 C/T cg05272587 chr13:111038400 COL4A2 0.38 7.71 0.38 1.41e-13 Bipolar disorder and schizophrenia; LIHC cis rs4728302 0.869 rs10253633 chr7:133590869 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs5753037 0.809 rs713657 chr22:30211876 A/G cg01021169 chr22:30184971 ASCC2 -0.37 -7.04 -0.36 1.07e-11 Type 1 diabetes; LIHC cis rs831571 0.774 rs40610 chr3:64009508 A/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.49 -6.48 -0.33 3.16e-10 Type 2 diabetes; LIHC cis rs12478296 1.000 rs60533128 chr2:243028088 A/G cg18898632 chr2:242989856 NA -0.7 -8.69 -0.43 1.5e-16 Obesity-related traits; LIHC cis rs12701220 0.553 rs34062359 chr7:1139076 C/T cg02733842 chr7:1102375 C7orf50 -0.75 -7.8 -0.39 7.76e-14 Bronchopulmonary dysplasia; LIHC cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg04267008 chr7:1944627 MAD1L1 -0.54 -8.49 -0.42 6.54e-16 Bipolar disorder and schizophrenia; LIHC cis rs1552244 0.554 rs7349576 chr3:10050893 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -8.02 -0.4 1.75e-14 Alzheimer's disease; LIHC cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg00149659 chr3:10157352 C3orf10 0.74 7.51 0.38 5.16e-13 Alzheimer's disease; LIHC cis rs16912285 0.748 rs12786638 chr11:24346006 A/G ch.11.24196551F chr11:24239977 NA 0.72 8.45 0.42 8.51e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg08859206 chr1:53392774 SCP2 0.36 5.98 0.31 5.76e-9 Monocyte count; LIHC cis rs1577917 0.740 rs7771612 chr6:86264374 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.11 0.44 7.14e-18 Response to antipsychotic treatment; LIHC cis rs10540 1.000 rs61876326 chr11:467368 A/G cg03576123 chr11:487126 PTDSS2 -1.0 -8.14 -0.4 7.3e-15 Body mass index; LIHC trans rs116095464 0.558 rs10057626 chr5:239720 T/G cg00938859 chr5:1591904 SDHAP3 0.56 6.95 0.35 1.8e-11 Breast cancer; LIHC cis rs10791097 0.694 rs1893018 chr11:130756632 T/C cg12179176 chr11:130786555 SNX19 0.85 13.94 0.6 2.63e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7584330 0.518 rs11884238 chr2:238424671 T/G cg08992911 chr2:238395768 MLPH 0.48 5.93 0.31 7.32e-9 Prostate cancer; LIHC cis rs780096 0.587 rs6743819 chr2:27567407 G/T cg27432699 chr2:27873401 GPN1 -0.48 -6.92 -0.35 2.3e-11 Total body bone mineral density; LIHC cis rs7937890 0.904 rs67623158 chr11:14295196 T/C cg06199346 chr11:14280333 SPON1 0.34 5.75 0.3 2.02e-8 Mitochondrial DNA levels; LIHC cis rs748404 0.697 rs574065 chr15:43550655 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.5 -8.62 -0.42 2.53e-16 Lung cancer; LIHC cis rs10857712 0.904 rs7083614 chr10:135226236 G/A cg19623624 chr10:135278901 LOC619207 -0.42 -6.56 -0.33 2.05e-10 Systemic lupus erythematosus; LIHC cis rs17685 0.712 rs28456330 chr7:75810542 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 2.01e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6952809 0.590 rs1468337 chr7:2432211 C/T cg23289794 chr7:2394357 EIF3B -0.65 -6.47 -0.33 3.4e-10 Multiple sclerosis; LIHC cis rs11098499 0.866 rs6847778 chr4:120293582 A/G cg09307838 chr4:120376055 NA 0.63 9.49 0.46 4.2e-19 Corneal astigmatism; LIHC cis rs6456156 0.603 rs2345754 chr6:167484361 T/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.51 -0.42 5.66e-16 Primary biliary cholangitis; LIHC cis rs9911578 0.692 rs412000 chr17:56709058 G/C cg12560992 chr17:57184187 TRIM37 0.67 8.88 0.43 3.94e-17 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.824 rs9321076 chr6:127655614 G/A cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC trans rs13202860 1.000 rs13193345 chr6:87187922 G/A cg27326224 chr7:950474 ADAP1 -0.57 -6.32 -0.32 8.05e-10 Sexual dysfunction (female); LIHC cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg06466757 chr4:1255808 NA 0.3 5.77 0.3 1.8e-8 Obesity-related traits; LIHC cis rs17152411 0.895 rs11245422 chr10:126588143 T/C cg07906193 chr10:126599966 NA 0.42 6.6 0.34 1.61e-10 Height; LIHC cis rs2066819 1.000 rs117683816 chr12:56638267 T/C cg26714650 chr12:56694279 CS -1.33 -12.81 -0.57 5.98e-31 Psoriasis vulgaris; LIHC cis rs7208859 0.623 rs9911490 chr17:29073013 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2832191 0.967 rs2832216 chr21:30521921 C/T cg08807101 chr21:30365312 RNF160 0.49 7.78 0.39 8.72e-14 Dental caries; LIHC cis rs7927592 0.763 rs10896340 chr11:68312645 A/G cg01657329 chr11:68192670 LRP5 0.5 7.43 0.37 8.55e-13 Total body bone mineral density; LIHC cis rs6938 0.618 rs11857695 chr15:75165751 G/T cg14664628 chr15:75095509 CSK -0.51 -7.33 -0.37 1.65e-12 Breast cancer; LIHC cis rs7909074 0.831 rs7903412 chr10:45382361 C/T cg05187965 chr10:45406764 TMEM72 -0.27 -6.83 -0.35 3.96e-11 Mean corpuscular volume; LIHC cis rs2180341 0.920 rs7756880 chr6:127683999 A/T cg27446573 chr6:127587934 RNF146 1.06 16.75 0.67 2.08e-46 Breast cancer; LIHC trans rs11098499 0.954 rs28572238 chr4:120316686 T/G cg25214090 chr10:38739885 LOC399744 0.58 9.18 0.44 4.22e-18 Corneal astigmatism; LIHC cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg08499158 chr17:42289980 UBTF -0.49 -7.99 -0.4 2.15e-14 Total body bone mineral density; LIHC cis rs6964587 1.000 rs2269727 chr7:91752690 C/A cg17063962 chr7:91808500 NA 1.02 19.53 0.73 1.39e-57 Breast cancer; LIHC cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg13699009 chr12:122356056 WDR66 0.62 9.32 0.45 1.51e-18 Mean corpuscular volume; LIHC cis rs367615 0.660 rs10477972 chr5:108831951 C/A cg17395555 chr5:108820864 NA 0.4 8.57 0.42 3.51e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs250677 0.524 rs183140 chr5:148438803 G/T cg18129178 chr5:148520854 ABLIM3 -0.36 -5.97 -0.31 5.83e-9 Breast cancer; LIHC cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs924607 0.900 rs1697950 chr5:616890 G/A cg04476341 chr5:669733 TPPP -0.39 -8.94 -0.44 2.39e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs12682352 0.579 rs7006589 chr8:8668486 A/G cg06636001 chr8:8085503 FLJ10661 0.45 6.65 0.34 1.17e-10 Neuroticism; LIHC trans rs11039798 0.920 rs61448762 chr11:48923756 G/A cg15704280 chr7:45808275 SEPT13 0.63 6.05 0.31 3.85e-9 Axial length; LIHC cis rs7539624 0.588 rs1892077 chr1:223895116 A/G cg07395969 chr1:223900822 CAPN2 0.49 5.77 0.3 1.76e-8 Schizophrenia; LIHC cis rs7089973 0.604 rs55759483 chr10:116573423 T/C cg23260525 chr10:116636907 FAM160B1 0.39 7.56 0.38 3.79e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9788682 1.000 rs34138960 chr15:78831668 A/G cg06917634 chr15:78832804 PSMA4 -0.53 -7.58 -0.38 3.27e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs7072216 0.763 rs7910247 chr10:100172252 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg13903179 chr13:21900392 NA 0.35 5.9 0.3 8.58e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg07308232 chr7:1071921 C7orf50 -0.46 -7.34 -0.37 1.6e-12 Longevity;Endometriosis; LIHC cis rs72772090 0.908 rs6864233 chr5:96044681 A/G cg17330273 chr5:96107758 CAST;ERAP1 0.52 6.17 0.32 1.97e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs1814175 0.817 rs12277258 chr11:49940216 T/C cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs9326248 0.501 rs4938351 chr11:117022352 A/C cg26566898 chr11:117069891 TAGLN 0.39 5.99 0.31 5.25e-9 Blood protein levels; LIHC cis rs6701037 1.000 rs11580331 chr1:175123288 T/C cg17845761 chr1:175162550 KIAA0040 -0.35 -5.8 -0.3 1.53e-8 Alcohol dependence; LIHC cis rs1949733 0.585 rs2631768 chr4:8473050 A/G cg11789530 chr4:8429930 ACOX3 -0.57 -7.59 -0.38 3.03e-13 Response to antineoplastic agents; LIHC cis rs7582180 0.638 rs7581011 chr2:100954659 A/G cg14675211 chr2:100938903 LONRF2 -0.54 -8.54 -0.42 4.51e-16 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg09904177 chr6:26538194 HMGN4 0.57 11.48 0.53 5.13e-26 Intelligence (multi-trait analysis); LIHC cis rs6879260 1.000 rs10903252 chr5:179733934 T/C cg13944838 chr5:179740914 GFPT2 -0.49 -6.73 -0.34 6.97e-11 Height; LIHC cis rs9457247 0.871 rs1811121 chr6:167403539 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.02 -0.51 2.23e-24 Crohn's disease; LIHC cis rs992157 0.560 rs6738394 chr2:219110625 G/A cg00012203 chr2:219082015 ARPC2 -0.89 -15.56 -0.64 1.14e-41 Colorectal cancer; LIHC cis rs13108904 0.557 rs1680041 chr4:1238521 C/T cg16405210 chr4:1374714 KIAA1530 0.7 10.44 0.49 2.57e-22 Obesity-related traits; LIHC cis rs2980436 1 rs2980436 chr8:8092025 A/G cg15556689 chr8:8085844 FLJ10661 -0.4 -5.91 -0.3 8.43e-9 Schizophrenia; LIHC cis rs3008870 1.000 rs17497828 chr1:67452322 G/A cg08660285 chr1:67390436 MIER1;WDR78 -0.92 -15.27 -0.64 1.67e-40 Lymphocyte percentage of white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21692936 chr11:62623994 SLC3A2;SNORD27;SNHG1;SNORD25;SNORD26 0.41 6.08 0.31 3.2e-9 Pancreatic cancer; LIHC cis rs11971779 0.816 rs11979272 chr7:139074069 C/T cg07862535 chr7:139043722 LUC7L2 0.69 11.21 0.52 4.77e-25 Diisocyanate-induced asthma; LIHC cis rs9916302 0.904 rs4794814 chr17:37696852 G/A cg15445000 chr17:37608096 MED1 0.38 5.83 0.3 1.26e-8 Glomerular filtration rate (creatinine); LIHC cis rs2153535 0.580 rs9393022 chr6:8466588 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs66573146 0.831 rs73088564 chr4:6984553 G/C cg00086871 chr4:6988644 TBC1D14 0.8 5.72 0.3 2.37e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs12479064 0.671 rs4851207 chr2:100105775 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.7 -8.46 -0.42 7.87e-16 Chronic sinus infection; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg22586474 chr7:931148 C7orf20 0.5 6.42 0.33 4.67e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs7246657 0.943 rs10404602 chr19:37825633 A/T cg23950597 chr19:37808831 NA -0.54 -7.04 -0.36 1.07e-11 Coronary artery calcification; LIHC cis rs72627509 0.904 rs17081933 chr4:57822869 T/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.58 -8.43 -0.41 9.61e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.5 -0.46 3.88e-19 Bipolar disorder; LIHC cis rs10751667 0.666 rs4074231 chr11:978219 G/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs765787 0.530 rs1706764 chr15:45524256 T/A cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.74 -0.3 2.12e-8 Uric acid levels; LIHC cis rs700651 0.856 rs9288280 chr2:198744324 A/G cg10820045 chr2:198174542 NA 0.49 7.5 0.38 5.48e-13 Intracranial aneurysm; LIHC cis rs5753037 0.834 rs713656 chr22:30212194 C/G cg01021169 chr22:30184971 ASCC2 -0.35 -6.62 -0.34 1.4e-10 Type 1 diabetes; LIHC cis rs9303401 0.703 rs8072182 chr17:57211213 G/A cg12560992 chr17:57184187 TRIM37 0.55 7.69 0.38 1.63e-13 Cognitive test performance; LIHC cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg12756686 chr19:29218302 NA 0.44 7.14 0.36 5.56e-12 Methadone dose in opioid dependence; LIHC trans rs13201877 0.591 rs3850212 chr6:137655120 A/G cg16624405 chr10:133607033 NA -0.43 -6.28 -0.32 1.03e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2115630 0.967 rs10438428 chr15:85330745 C/T cg09876464 chr15:85330779 ZNF592 0.35 5.97 0.31 5.87e-9 P wave terminal force; LIHC cis rs62458065 0.640 rs10241303 chr7:32534203 T/G cg20159608 chr7:32802032 NA -0.49 -5.72 -0.3 2.3e-8 Metabolite levels (HVA/MHPG ratio); LIHC cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg25072359 chr17:41440525 NA 0.38 6.1 0.31 2.85e-9 Menopause (age at onset); LIHC cis rs7224737 1.000 rs2014521 chr17:40283413 C/G cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.24e-9 Fibrinogen levels; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.15 0.55 1.79e-28 Prudent dietary pattern; LIHC cis rs1707322 1.000 rs1707317 chr1:46510642 C/T cg06784218 chr1:46089804 CCDC17 -0.39 -7.06 -0.36 9.43e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs992157 1.000 rs6736362 chr2:219115108 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.75 0.57 1.03e-30 Colorectal cancer; LIHC cis rs6952808 0.862 rs4721135 chr7:1912222 A/G cg02951883 chr7:2050386 MAD1L1 -0.51 -7.75 -0.39 1.05e-13 Bipolar disorder and schizophrenia; LIHC trans rs1814175 0.781 rs1851872 chr11:50009770 A/G cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC trans rs35110281 0.782 rs2051407 chr21:45079245 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.47 0.33 3.37e-10 Mean corpuscular volume; LIHC cis rs57590327 0.503 rs1464790 chr3:81852923 A/T cg07356753 chr3:81810745 GBE1 0.51 7.97 0.4 2.39e-14 Extraversion; LIHC cis rs4722166 0.599 rs7776857 chr7:22754768 G/T cg05472934 chr7:22766657 IL6 0.6 8.7 0.43 1.4e-16 Lung cancer; LIHC cis rs2991971 0.810 rs998199 chr1:45912898 A/C cg05343316 chr1:45956843 TESK2 0.45 6.6 0.34 1.53e-10 High light scatter reticulocyte count; LIHC cis rs514406 0.792 rs481440 chr1:53344976 C/T cg24675658 chr1:53192096 ZYG11B -0.6 -8.14 -0.4 7.64e-15 Monocyte count; LIHC cis rs116095464 0.558 rs10055354 chr5:243794 G/A cg22496380 chr5:211416 CCDC127 -0.99 -10.7 -0.5 3.14e-23 Breast cancer; LIHC cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.541 rs7603816 chr2:219396255 C/T cg02176678 chr2:219576539 TTLL4 -0.55 -7.7 -0.38 1.5e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs6831352 0.589 rs2924584 chr4:99988208 A/G cg12011299 chr4:100065546 ADH4 0.47 11.34 0.52 1.63e-25 Alcohol dependence; LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg19635926 chr16:89946313 TCF25 0.48 6.46 0.33 3.67e-10 Skin colour saturation; LIHC cis rs17106184 1.000 rs72900932 chr1:51107959 T/C cg07174182 chr1:51127561 FAF1 -0.65 -7.04 -0.36 1.03e-11 Type 2 diabetes; LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg02290350 chr8:58132656 NA 0.52 10.83 0.51 1.03e-23 Developmental language disorder (linguistic errors); LIHC cis rs12477438 1.000 rs73963398 chr2:99887025 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.94 -11.29 -0.52 2.44e-25 Chronic sinus infection; LIHC trans rs1814175 0.715 rs10839409 chr11:49884647 G/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.18 -0.78 3.99e-72 Height; LIHC cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg09222892 chr1:25734099 RHCE -0.47 -8.77 -0.43 8.75e-17 Erythrocyte sedimentation rate; LIHC cis rs2997447 0.761 rs61776618 chr1:26456709 A/G cg19633962 chr1:26362018 EXTL1 -0.65 -5.76 -0.3 1.87e-8 QRS complex (12-leadsum); LIHC cis rs77637988 0.603 rs72820445 chr2:48607856 T/C cg15846641 chr2:48541264 FOXN2 0.58 7.93 0.39 3.05e-14 Joint mobility (Beighton score); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12880967 chr11:63804044 MACROD1 0.46 6.05 0.31 3.9e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2153535 0.541 rs7774752 chr6:8468978 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs9325144 0.647 rs3759139 chr12:39087609 G/A cg26384229 chr12:38710491 ALG10B -0.41 -5.79 -0.3 1.56e-8 Morning vs. evening chronotype; LIHC trans rs637571 0.726 rs669371 chr11:65674153 G/T cg17712092 chr4:129076599 LARP1B -0.7 -10.7 -0.5 3.16e-23 Eosinophil percentage of white cells; LIHC cis rs9911578 1.000 rs9907499 chr17:56949044 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs950169 0.545 rs4354897 chr15:84644971 T/C cg17507749 chr15:85114479 UBE2QP1 0.63 5.81 0.3 1.42e-8 Schizophrenia; LIHC cis rs4820294 0.646 rs9622675 chr22:38053665 G/T cg00292662 chr22:38071168 LGALS1 0.4 6.7 0.34 8.65e-11 Fat distribution (HIV); LIHC cis rs1577917 0.958 rs12192033 chr6:86472559 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.89 -0.3 9.1e-9 Response to antipsychotic treatment; LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg06601766 chr17:61851465 DDX42;CCDC47 -0.46 -7.21 -0.36 3.59e-12 Prudent dietary pattern; LIHC cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg11062466 chr8:58055876 NA 0.4 5.8 0.3 1.53e-8 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.85 0.3 1.12e-8 Menopause (age at onset); LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg07157834 chr1:205819609 PM20D1 0.58 8.67 0.42 1.75e-16 Menarche (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg15803506 chr10:135125704 ZNF511 0.4 6.17 0.32 1.95e-9 Longevity; LIHC cis rs12135062 0.851 rs2651927 chr1:3101762 A/C cg25382214 chr1:3105252 PRDM16 -0.27 -6.13 -0.31 2.38e-9 Migraine; LIHC cis rs894734 0.535 rs2366142 chr12:54323148 T/C cg17708016 chr12:54321992 NA 0.42 7.3 0.37 2e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs561341 1.000 rs113115092 chr17:30284164 G/A cg00745463 chr17:30367425 LRRC37B -0.77 -5.71 -0.3 2.43e-8 Hip circumference adjusted for BMI; LIHC cis rs769267 0.896 rs10410664 chr19:19556651 G/A cg03709012 chr19:19516395 GATAD2A 1.03 18.52 0.71 1.52e-53 Tonsillectomy; LIHC cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.58 -0.34 1.79e-10 Gut microbiome composition (summer); LIHC cis rs11676348 0.710 rs11894169 chr2:219046846 T/C cg00012203 chr2:219082015 ARPC2 0.51 6.69 0.34 9.33e-11 Ulcerative colitis; LIHC cis rs36051895 0.623 rs2146041 chr9:5262911 A/G cg02405213 chr9:5042618 JAK2 -0.65 -10.79 -0.5 1.5e-23 Pediatric autoimmune diseases; LIHC cis rs9443189 1.000 rs6906615 chr6:76489774 A/G cg01950844 chr6:76311363 SENP6 0.47 5.78 0.3 1.69e-8 Prostate cancer; LIHC cis rs9328573 0.685 rs2006990 chr15:100508462 C/G cg09918751 chr15:100517450 ADAMTS17 -0.42 -6.43 -0.33 4.31e-10 Urate levels in lean individuals; LIHC cis rs1577917 1.000 rs955227 chr6:86651032 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.24 -0.48 1.19e-21 Response to antipsychotic treatment; LIHC cis rs6942756 0.737 rs61570833 chr7:128933492 C/A cg02491457 chr7:128862824 NA -0.63 -8.98 -0.44 1.8e-17 White matter hyperintensity burden; LIHC trans rs3780486 0.801 rs56687083 chr9:33132134 A/G cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs875971 0.798 rs7789615 chr7:65878661 A/G cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC cis rs7772486 0.875 rs1412081 chr6:146409733 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.73 0.3 2.26e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7520050 0.966 rs12410071 chr1:46358886 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.78 0.3 1.69e-8 Red blood cell count;Reticulocyte count; LIHC cis rs3736757 0.664 rs12567225 chr1:184678272 A/G cg07817967 chr1:184721222 EDEM3 -0.35 -5.78 -0.3 1.7e-8 Obesity-related traits; LIHC cis rs9325144 0.647 rs17518186 chr12:38883665 T/C cg26384229 chr12:38710491 ALG10B -0.56 -7.58 -0.38 3.24e-13 Morning vs. evening chronotype; LIHC cis rs529866 0.519 rs4451969 chr16:11383519 A/G cg00044050 chr16:11439710 C16orf75 -0.42 -5.86 -0.3 1.07e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7651039 0.619 rs924814 chr3:15649550 G/A cg16303742 chr3:15540471 COLQ 0.58 10.46 0.49 2.14e-22 Coronary heart disease; LIHC cis rs12493885 0.818 rs10935970 chr3:153770237 C/G cg10247383 chr3:153839028 SGEF 0.65 6.13 0.31 2.41e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg18252515 chr7:66147081 NA 1.3 16.95 0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs11098699 0.950 rs11098700 chr4:124193531 G/C cg09941581 chr4:124220074 SPATA5 0.3 5.72 0.3 2.29e-8 Mosquito bite size; LIHC cis rs12188164 0.812 rs9313065 chr5:423426 T/C cg10655629 chr5:480253 SLC9A3 0.36 5.77 0.3 1.77e-8 Cystic fibrosis severity; LIHC cis rs546131 0.614 rs473885 chr11:34851961 G/A cg06937548 chr11:34938143 PDHX;APIP 0.57 7.45 0.37 7.55e-13 Lung disease severity in cystic fibrosis; LIHC cis rs7107174 1.000 rs10899469 chr11:78018313 T/C cg02023728 chr11:77925099 USP35 0.52 9.96 0.47 1.13e-20 Testicular germ cell tumor; LIHC cis rs644148 0.730 rs2571044 chr19:44985573 G/A cg15540054 chr19:45004280 ZNF180 -0.71 -9.87 -0.47 2.25e-20 Personality dimensions; LIHC cis rs6762 0.748 rs28636471 chr11:840639 T/A cg15787769 chr11:842744 TSPAN4;POLR2L -0.67 -8.1 -0.4 9.91e-15 Mean platelet volume; LIHC trans rs2727020 0.595 rs7924311 chr11:49507573 G/A cg18944383 chr4:111397179 ENPEP 0.25 6.33 0.32 7.77e-10 Coronary artery disease; LIHC cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg18252515 chr7:66147081 NA 1.27 16.79 0.67 1.38e-46 Diabetic kidney disease; LIHC cis rs7762018 0.556 rs78864023 chr6:170059755 T/A cg19338460 chr6:170058176 WDR27 -0.91 -10.28 -0.49 8.74e-22 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs507080 0.922 rs4474473 chr11:118553889 T/G cg04173919 chr11:118528438 PHLDB1 0.33 6.24 0.32 1.33e-9 Serum metabolite levels; LIHC cis rs2576037 0.583 rs2571028 chr18:44561100 C/G cg19077165 chr18:44547161 KATNAL2 0.46 6.82 0.35 4.19e-11 Personality dimensions; LIHC cis rs12824058 0.737 rs11060829 chr12:130814996 G/T cg26677194 chr12:130822605 PIWIL1 0.52 7.39 0.37 1.15e-12 Menopause (age at onset); LIHC cis rs9394841 0.667 rs9357366 chr6:41786976 T/G cg17623882 chr6:41773611 USP49 -0.43 -5.85 -0.3 1.13e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs597539 0.652 rs553875 chr11:68695144 T/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.22 0.48 1.39e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7953508 0.711 rs11107116 chr12:93978504 G/T cg18151635 chr12:93972918 NA -0.48 -7.37 -0.37 1.28e-12 Pubertal anthropometrics; LIHC cis rs600231 0.706 rs3782091 chr11:65336483 G/T cg17120908 chr11:65337727 SSSCA1 0.47 6.81 0.35 4.34e-11 Bone mineral density; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg09367891 chr1:107599246 PRMT6 -0.72 -11.98 -0.54 7.39e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7772486 0.875 rs9399573 chr6:146403255 A/T cg05347473 chr6:146136440 FBXO30 0.35 5.81 0.3 1.46e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618501 0.633 rs6771546 chr3:49968572 T/C cg24110177 chr3:50126178 RBM5 -0.47 -7.67 -0.38 1.86e-13 Intelligence (multi-trait analysis); LIHC cis rs68092024 0.731 rs792840 chr3:99471251 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.44 -6.1 -0.31 2.8e-9 Cleft lip with or without cleft palate; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg13700589 chr9:15511220 PSIP1 -0.51 -6.55 -0.33 2.13e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1577917 0.771 rs6454486 chr6:86433587 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.53 10.33 0.49 6.02e-22 Response to antipsychotic treatment; LIHC cis rs7208859 0.573 rs11656278 chr17:29075188 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1577917 0.796 rs12661231 chr6:86544471 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.46 -0.37 7e-13 Response to antipsychotic treatment; LIHC cis rs7772486 0.686 rs857877 chr6:145976230 A/C cg23711669 chr6:146136114 FBXO30 -0.7 -12.65 -0.56 2.45e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs55665837 0.502 rs4757269 chr11:14836192 A/C cg19336497 chr11:14380999 RRAS2 -0.34 -5.74 -0.3 2.14e-8 Vitamin D levels; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC cis rs3806843 0.900 rs2531340 chr5:140131046 C/T cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7408868 0.908 rs4809028 chr19:15273231 A/G cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC cis rs4822044 0.617 rs13054514 chr22:42130383 A/G cg06634786 chr22:41940651 POLR3H 0.56 6.18 0.32 1.87e-9 Cannabis dependence symptom count; LIHC cis rs2730245 0.550 rs2657364 chr7:158683825 T/C cg24397884 chr7:158709396 WDR60 0.41 6.1 0.31 2.81e-9 Height; LIHC cis rs10489202 1.000 rs7538251 chr1:168001752 C/G cg24449463 chr1:168025552 DCAF6 -0.53 -6.59 -0.34 1.65e-10 Schizophrenia; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg00703542 chr5:145583510 RBM27 0.47 6.36 0.33 6.62e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs1814175 0.645 rs7928714 chr11:49887622 G/A cg15704280 chr7:45808275 SEPT13 -0.95 -19.73 -0.73 2.22e-58 Height; LIHC cis rs68170813 0.559 rs12537342 chr7:106943563 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs7238033 0.624 rs4310958 chr18:43309355 C/G cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs6815814 0.950 rs67719080 chr4:38787252 A/G cg06935464 chr4:38784597 TLR10 0.54 9.16 0.44 4.81e-18 Breast cancer; LIHC cis rs6952809 0.532 rs2057840 chr7:2432797 C/G cg23289794 chr7:2394357 EIF3B -0.58 -6.12 -0.31 2.53e-9 Multiple sclerosis; LIHC cis rs8062405 0.755 rs4788076 chr16:28570005 C/T cg07451762 chr16:28383216 NA 0.4 7.29 0.37 2.22e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6450176 1.000 rs60652351 chr5:53306140 T/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.66 -0.62 4.37e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6500602 0.653 rs4786488 chr16:4442527 C/T cg08645402 chr16:4508243 NA 0.38 6.37 0.33 6.16e-10 Schizophrenia; LIHC cis rs858239 0.539 rs870476 chr7:23193271 C/T cg23682824 chr7:23144976 KLHL7 0.42 6.37 0.33 6.09e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2842992 0.830 rs2842974 chr6:160159034 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.5 8.88 0.43 3.73e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs11098499 0.874 rs13139045 chr4:120168588 T/C cg09307838 chr4:120376055 NA 0.63 9.26 0.45 2.28e-18 Corneal astigmatism; LIHC cis rs6582630 0.572 rs1969363 chr12:38514872 A/G cg26384229 chr12:38710491 ALG10B 0.38 5.99 0.31 5.34e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs9470366 0.527 rs733590 chr6:36645203 A/G cg00935119 chr6:36647544 CDKN1A -0.45 -6.39 -0.33 5.46e-10 QRS duration; LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs2806561 0.704 rs674386 chr1:23521835 G/A cg11953164 chr1:23521307 HTR1D 0.29 5.78 0.3 1.68e-8 Height; LIHC cis rs6693567 0.826 rs1260387 chr1:150371448 T/C cg15654264 chr1:150340011 RPRD2 0.43 6.26 0.32 1.14e-9 Migraine; LIHC cis rs826838 0.967 rs12823908 chr12:38845686 T/C cg26384229 chr12:38710491 ALG10B 0.98 13.29 0.58 8.46e-33 Heart rate; LIHC cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg03806693 chr22:41940476 POLR3H -1.04 -11.94 -0.54 1.04e-27 Vitiligo; LIHC cis rs1008375 1.000 rs56308330 chr4:17643050 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.82 0.3 1.36e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10751667 0.961 rs6597953 chr11:991099 G/A ch.11.42038R chr11:967971 AP2A2 0.59 10.92 0.51 5.28e-24 Alzheimer's disease (late onset); LIHC cis rs9914988 0.887 rs11650282 chr17:27090741 C/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.96 -0.35 1.79e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs965469 1.000 rs6051712 chr20:3265029 T/A cg25506879 chr20:3388711 C20orf194 -0.57 -6.96 -0.35 1.79e-11 IFN-related cytopenia; LIHC cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 8.73 0.43 1.13e-16 Platelet count; LIHC cis rs1003719 0.646 rs2032063 chr21:38576657 A/T cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs15676 0.783 rs2977995 chr9:131584245 A/G cg00228799 chr9:131580591 ENDOG 0.48 6.99 0.35 1.44e-11 Blood metabolite levels; LIHC cis rs2952156 1.000 rs1565923 chr17:37858678 A/G cg00129232 chr17:37814104 STARD3 -0.48 -8.67 -0.42 1.75e-16 Asthma; LIHC cis rs9393692 0.905 rs7761298 chr6:26278436 C/T cg05868516 chr6:26286170 HIST1H4H 0.41 6.31 0.32 8.62e-10 Educational attainment; LIHC cis rs1707322 0.964 rs6675259 chr1:46502295 G/A cg03146154 chr1:46216737 IPP -0.47 -7.32 -0.37 1.8e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.85 0.51 9.05e-24 Colorectal cancer; LIHC cis rs73206853 0.640 rs3825390 chr12:110976409 A/C cg12870014 chr12:110450643 ANKRD13A 0.77 8.87 0.43 4e-17 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs61990749 0.597 rs9323650 chr14:78150336 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.55 9.16 0.44 4.79e-18 Fibroblast growth factor basic levels; LIHC cis rs11958404 0.789 rs72818145 chr5:157476552 G/C cg05962755 chr5:157440814 NA 1.0 11.73 0.54 6.05e-27 IgG glycosylation; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg22280406 chr17:78582647 RPTOR 0.45 6.18 0.32 1.81e-9 Hepatitis; LIHC cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs826838 1.000 rs851934 chr12:39104453 G/T cg13010199 chr12:38710504 ALG10B -0.4 -5.88 -0.3 9.59e-9 Heart rate; LIHC cis rs611744 0.647 rs2597658 chr8:109256014 C/T cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg20295408 chr7:1910781 MAD1L1 -0.49 -7.05 -0.36 9.9e-12 Bipolar disorder and schizophrenia; LIHC cis rs11958404 0.932 rs59246968 chr5:157418180 T/C cg05962755 chr5:157440814 NA 0.91 10.22 0.48 1.37e-21 IgG glycosylation; LIHC cis rs9733 0.818 rs11204695 chr1:150657011 T/G cg17724175 chr1:150552817 MCL1 -0.37 -7.7 -0.38 1.45e-13 Tonsillectomy; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg03248799 chr12:56510114 RPL41 0.39 6.29 0.32 9.76e-10 Metabolic traits; LIHC cis rs35146811 0.844 rs59261051 chr7:99650429 C/T cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.42 5.97 0.31 5.96e-9 Coronary artery disease; LIHC cis rs1005277 0.579 rs2505196 chr10:38393563 G/A cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.687 rs2320523 chr12:38251397 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.52 0.49 1.35e-22 Bladder cancer; LIHC cis rs1538970 0.924 rs10890327 chr1:45891458 C/T cg05343316 chr1:45956843 TESK2 0.57 8.34 0.41 1.85e-15 Platelet count; LIHC cis rs6594499 0.903 rs1438672 chr5:110467753 G/A cg04022379 chr5:110408740 TSLP 0.5 8.31 0.41 2.32e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2066819 1.000 rs11575231 chr12:56744445 T/C cg26734620 chr12:56694298 CS 1.21 10.14 0.48 2.67e-21 Psoriasis vulgaris; LIHC cis rs15676 0.783 rs2997917 chr9:131586918 G/A cg00228799 chr9:131580591 ENDOG 0.48 6.92 0.35 2.19e-11 Blood metabolite levels; LIHC cis rs7523273 0.925 rs4844394 chr1:208000625 C/T cg22525895 chr1:207977042 MIR29B2 -0.69 -10.59 -0.5 7.74e-23 Schizophrenia; LIHC cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.03 0.31 4.21e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg00656387 chr3:40428638 ENTPD3 0.43 6.96 0.35 1.7e-11 Renal cell carcinoma; LIHC cis rs6684514 1.000 rs12023704 chr1:156294149 C/A cg16558208 chr1:156270281 VHLL 0.55 10.39 0.49 3.56e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg20399509 chr21:47717575 C21orf57 -0.37 -5.96 -0.31 6.22e-9 Testicular germ cell tumor; LIHC cis rs8062405 0.723 rs113208333 chr16:28606160 G/T cg00204512 chr16:28754710 NA 0.43 7.45 0.37 7.78e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7044106 0.791 rs10985008 chr9:123492960 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.77 13.07 0.58 6.15e-32 Hip circumference adjusted for BMI; LIHC cis rs11958404 0.615 rs10053795 chr5:157449185 T/C cg05962755 chr5:157440814 NA 0.54 6.73 0.34 6.97e-11 IgG glycosylation; LIHC cis rs763121 0.853 rs2294296 chr22:39053049 T/C cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs2845885 0.793 rs35927325 chr11:63882495 C/T cg19006947 chr11:64034861 PLCB3 -0.59 -8.5 -0.42 5.97e-16 Body mass index; LIHC cis rs9457247 0.534 rs2757053 chr6:167380338 A/C cg12798992 chr6:167411361 FGFR1OP -0.47 -7.68 -0.38 1.73e-13 Crohn's disease; LIHC cis rs798554 0.680 rs1713912 chr7:2895784 C/A cg13628971 chr7:2884303 GNA12 0.58 9.64 0.46 1.27e-19 Height; LIHC cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg05665937 chr4:1216051 CTBP1 0.45 6.29 0.32 9.72e-10 Obesity-related traits; LIHC cis rs11677370 0.603 rs10171309 chr2:3851690 C/T cg17052675 chr2:3827356 NA -0.54 -6.97 -0.35 1.6e-11 Type 2 diabetes; LIHC cis rs9914988 0.943 rs2046759 chr17:27138817 T/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.77 13.05 0.58 7.2e-32 Prudent dietary pattern; LIHC cis rs7312933 0.576 rs11181364 chr12:42567800 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.78 0.39 8.74e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs28735056 0.967 rs11662248 chr18:77619009 C/T cg20368463 chr18:77673604 PQLC1 -0.39 -6.93 -0.35 2.16e-11 Schizophrenia; LIHC cis rs265548 0.538 rs36688 chr19:17911212 A/C cg21960279 chr19:17905606 B3GNT3 0.54 8.42 0.41 1.04e-15 Tumor biomarkers; LIHC cis rs4788570 0.615 rs8053745 chr16:71689693 A/G cg06353428 chr16:71660113 MARVELD3 1.43 14.99 0.63 2.2e-39 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.814 rs9321085 chr6:127735361 T/C cg24812749 chr6:127587940 RNF146 0.79 12.59 0.56 4.04e-30 Breast cancer; LIHC cis rs992157 1.000 rs13003334 chr2:219124921 T/A cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.88 0.57 3.23e-31 Colorectal cancer; LIHC cis rs7615952 0.599 rs12486459 chr3:125741465 T/G cg05084668 chr3:125655381 ALG1L -0.41 -6.39 -0.33 5.28e-10 Blood pressure (smoking interaction); LIHC cis rs2629540 1.000 rs2629540 chr10:126426148 G/C cg08799069 chr10:126477246 METTL10 0.47 7.16 0.36 4.9e-12 Cocaine dependence; LIHC cis rs6450176 1.000 rs59061738 chr5:53296557 A/G ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs7208859 0.623 rs11652533 chr17:29060601 A/C cg13385521 chr17:29058706 SUZ12P 0.84 8.37 0.41 1.49e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2235642 0.928 rs9932984 chr16:1605051 A/G cg09025071 chr16:1593152 IFT140;TMEM204 0.29 5.74 0.3 2.12e-8 Coronary artery disease; LIHC cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg15382696 chr6:118971807 C6orf204 0.64 6.24 0.32 1.28e-9 Diastolic blood pressure; LIHC cis rs4332037 0.539 rs34571717 chr7:2106855 T/C cg23043544 chr7:2124092 MAD1L1 -0.4 -6.3 -0.32 9.28e-10 Bipolar disorder; LIHC cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg06634786 chr22:41940651 POLR3H 0.83 9.16 0.44 4.85e-18 Vitiligo; LIHC cis rs10751667 0.666 rs7944815 chr11:959776 C/T cg10932868 chr11:921992 NA 0.39 7.27 0.37 2.53e-12 Alzheimer's disease (late onset); LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.21 0.55 1.08e-28 Prudent dietary pattern; LIHC trans rs783540 0.867 rs7167880 chr15:83294436 G/A cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.27 -0.32 1.06e-9 Schizophrenia; LIHC cis rs344364 0.511 rs1742464 chr16:1947335 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 0.53 6.85 0.35 3.35e-11 Glomerular filtration rate in chronic kidney disease; LIHC cis rs5769765 0.773 rs6520065 chr22:50294470 A/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.15 -0.44 5.12e-18 Schizophrenia; LIHC cis rs1046896 1.000 rs28485881 chr17:80690014 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.46 6.94 0.35 1.93e-11 Glycated hemoglobin levels; LIHC cis rs9325144 0.647 rs61930266 chr12:38922048 A/G cg26384229 chr12:38710491 ALG10B -0.49 -6.96 -0.35 1.72e-11 Morning vs. evening chronotype; LIHC cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg21951975 chr1:209979733 IRF6 0.45 7.23 0.36 3.28e-12 Cleft lip with or without cleft palate; LIHC cis rs1707322 0.963 rs10890371 chr1:46390897 T/G cg03146154 chr1:46216737 IPP 0.47 7.62 0.38 2.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.54 -9.42 -0.45 7.15e-19 Electroencephalogram traits; LIHC cis rs12478296 0.581 rs4973645 chr2:242993577 T/C cg06360820 chr2:242988706 NA -0.91 -12.87 -0.57 3.43e-31 Obesity-related traits; LIHC cis rs6502050 0.769 rs9916231 chr17:80119645 A/G cg11859384 chr17:80120422 CCDC57 -0.49 -7.0 -0.35 1.33e-11 Life satisfaction; LIHC cis rs1552244 0.882 rs13066757 chr3:10045030 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.54 0.5 1.07e-22 Alzheimer's disease; LIHC cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg04369109 chr6:150039330 LATS1 -0.37 -5.89 -0.3 9.1e-9 Lung cancer; LIHC cis rs10489202 0.955 rs17557162 chr1:167985950 A/T cg24449463 chr1:168025552 DCAF6 0.57 7.36 0.37 1.42e-12 Schizophrenia; LIHC cis rs10751667 1.000 rs6597965 chr11:964476 A/G ch.11.42038R chr11:967971 AP2A2 0.61 11.47 0.53 5.46e-26 Alzheimer's disease (late onset); LIHC cis rs5758659 1.000 rs5751255 chr22:42648408 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.39 -7.43 -0.37 8.85e-13 Cognitive function; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17445840 chr3:101546486 FAM55C;NFKBIZ 0.46 6.94 0.35 1.93e-11 Lung function (FEV1/FVC); LIHC cis rs7618501 1.000 rs7372725 chr3:49790544 C/A cg21467203 chr3:49911342 NA 0.39 6.64 0.34 1.2e-10 Intelligence (multi-trait analysis); LIHC cis rs273218 1.000 rs274366 chr5:53374636 C/G ch.5.1024479R chr5:53302184 ARL15 0.68 10.92 0.51 5.17e-24 Migraine; LIHC cis rs1401454 1.000 rs1401454 chr11:16250183 C/T cg10927848 chr11:16298618 SOX6 -0.33 -6.15 -0.32 2.21e-9 Blood pressure; LIHC cis rs875971 0.862 rs1968126 chr7:66057004 A/G cg18252515 chr7:66147081 NA 0.45 6.57 0.33 1.87e-10 Aortic root size; LIHC cis rs67478160 0.643 rs8005225 chr14:104300151 C/T cg01849466 chr14:104193079 ZFYVE21 0.46 7.45 0.37 7.9e-13 Schizophrenia; LIHC cis rs9818758 0.556 rs9813813 chr3:49207093 T/A cg00383909 chr3:49044727 WDR6 1.1 7.92 0.39 3.47e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg26939375 chr7:64535504 NA 0.47 7.13 0.36 5.83e-12 Aortic root size; LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs6988636 1.000 rs6988636 chr8:124185970 A/G cg15893493 chr8:124194847 FAM83A 0.89 8.19 0.4 5.44e-15 Urinary uromodulin levels; LIHC cis rs9486719 1.000 rs12193732 chr6:96942609 G/A cg06623918 chr6:96969491 KIAA0776 -0.66 -6.7 -0.34 8.85e-11 Migraine;Coronary artery disease; LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg11070056 chr1:107600091 PRMT6 0.61 9.62 0.46 1.54e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9649213 0.511 rs6950994 chr7:97887872 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.41 -6.24 -0.32 1.33e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs1814175 0.817 rs28502006 chr11:50049930 T/C cg15704280 chr7:45808275 SEPT13 -1.0 -23.71 -0.79 3.38e-74 Height; LIHC cis rs2836950 0.501 rs2836980 chr21:40687618 G/T cg06238570 chr21:40685208 BRWD1 -0.48 -7.95 -0.4 2.66e-14 Menarche (age at onset); LIHC cis rs2239547 0.522 rs9311485 chr3:52987645 T/G cg11645453 chr3:52864694 ITIH4 -0.23 -5.86 -0.3 1.11e-8 Schizophrenia; LIHC cis rs7258465 1.000 rs10405636 chr19:18538742 A/C cg10790698 chr19:18539756 SSBP4 -0.36 -7.35 -0.37 1.49e-12 Breast cancer; LIHC cis rs2637266 1.000 rs2894339 chr10:78354104 G/A cg18941641 chr10:78392320 NA 0.29 6.06 0.31 3.54e-9 Pulmonary function; LIHC cis rs67478160 0.643 rs2295145 chr14:104202304 G/A cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.89 -0.39 4.23e-14 Schizophrenia; LIHC cis rs7677751 0.806 rs4864859 chr4:55090015 A/G cg17187183 chr4:55093834 PDGFRA 0.66 8.34 0.41 1.85e-15 Corneal astigmatism; LIHC cis rs1005277 0.522 rs1208684 chr10:38093936 G/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.88 -0.47 2.03e-20 Extrinsic epigenetic age acceleration; LIHC cis rs7617773 0.780 rs13079728 chr3:48339360 A/G cg11946769 chr3:48343235 NME6 0.91 11.44 0.53 7.06e-26 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09755102 chr1:33283495 S100PBP;YARS 0.42 6.56 0.33 1.98e-10 Pancreatic cancer; LIHC cis rs5769765 0.565 rs8137232 chr22:50256885 G/C cg09182678 chr22:50328711 NA 0.47 6.0 0.31 5.14e-9 Schizophrenia; LIHC cis rs4237845 0.773 rs6650218 chr12:58289078 T/A cg04478727 chr12:58166393 METTL1;FAM119B 0.43 5.95 0.31 6.68e-9 Intelligence (multi-trait analysis); LIHC cis rs7223966 1.000 rs8077265 chr17:61732727 A/G cg05941027 chr17:61774174 LIMD2 0.29 5.81 0.3 1.46e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7264396 0.690 rs2425180 chr20:34447160 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.83 -0.51 1.07e-23 Total cholesterol levels; LIHC cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg12756686 chr19:29218302 NA 0.44 6.79 0.34 4.88e-11 Methadone dose in opioid dependence; LIHC cis rs7100689 0.646 rs1890889 chr10:82090827 G/T cg00277334 chr10:82204260 NA -0.55 -6.98 -0.35 1.53e-11 Post bronchodilator FEV1; LIHC cis rs9326248 0.954 rs8521 chr11:117067699 C/T cg26566898 chr11:117069891 TAGLN 0.48 7.46 0.37 7.41e-13 Blood protein levels; LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg13012494 chr21:47604986 C21orf56 -0.38 -5.83 -0.3 1.31e-8 Testicular germ cell tumor; LIHC cis rs1577917 0.958 rs1545376 chr6:86504582 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.34 5.97 0.31 5.96e-9 Response to antipsychotic treatment; LIHC cis rs7618501 0.602 rs2624816 chr3:50117312 T/G cg21467203 chr3:49911342 NA 0.44 7.83 0.39 6.17e-14 Intelligence (multi-trait analysis); LIHC cis rs7020830 0.571 rs7031314 chr9:37376122 A/T cg14294708 chr9:37120828 ZCCHC7 -0.76 -10.14 -0.48 2.66e-21 Schizophrenia; LIHC cis rs568617 0.716 rs111953392 chr11:65595697 G/A cg04055107 chr11:65626734 MUS81;CFL1 0.58 5.86 0.3 1.09e-8 Crohn's disease; LIHC cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg05896524 chr21:47604654 C21orf56 0.49 7.87 0.39 4.75e-14 Testicular germ cell tumor; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg20132801 chr8:48172283 KIAA0146 0.43 6.52 0.33 2.55e-10 Immature fraction of reticulocytes; LIHC cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg06634786 chr22:41940651 POLR3H 0.74 7.71 0.38 1.41e-13 Vitiligo; LIHC cis rs17376456 0.877 rs13156865 chr5:93390908 C/A cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC trans rs36022378 0.504 rs4688688 chr3:50042690 C/G cg21659725 chr3:3221576 CRBN -0.54 -6.66 -0.34 1.1e-10 Diastolic blood pressure; LIHC cis rs2180341 0.960 rs9401953 chr6:127687574 G/A cg24812749 chr6:127587940 RNF146 1.03 15.33 0.64 9.68e-41 Breast cancer; LIHC trans rs1814175 0.527 rs7128827 chr11:49665644 C/T cg18944383 chr4:111397179 ENPEP -0.34 -7.82 -0.39 6.4e-14 Height; LIHC cis rs4474465 1.000 rs11604969 chr11:78179293 C/T cg27205649 chr11:78285834 NARS2 0.38 5.94 0.31 6.97e-9 Alzheimer's disease (survival time); LIHC cis rs936229 0.813 rs8033381 chr15:75080685 G/A cg14664628 chr15:75095509 CSK -1.01 -20.16 -0.74 4.04e-60 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg02782426 chr3:40428986 ENTPD3 0.34 6.25 0.32 1.23e-9 Renal cell carcinoma; LIHC trans rs62103177 0.564 rs59188178 chr18:77723435 T/C cg05926928 chr17:57297772 GDPD1 0.65 6.95 0.35 1.83e-11 Opioid sensitivity; LIHC cis rs7818688 0.654 rs75680386 chr8:95986148 A/G cg16049864 chr8:95962084 TP53INP1 0.6 6.49 0.33 2.99e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1005277 0.579 rs1740737 chr10:38499365 G/T cg00409905 chr10:38381863 ZNF37A -0.57 -9.57 -0.46 2.16e-19 Extrinsic epigenetic age acceleration; LIHC cis rs6831352 0.877 rs28987101 chr4:100049253 T/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs4820294 0.516 rs12627973 chr22:38096697 A/G cg00142150 chr22:38071001 LGALS1 0.63 8.18 0.4 5.5e-15 Fat distribution (HIV); LIHC cis rs67311347 1.000 rs10510708 chr3:40404770 A/G cg09455208 chr3:40491958 NA 0.32 6.41 0.33 4.74e-10 Renal cell carcinoma; LIHC trans rs2243480 1.000 rs316313 chr7:65593548 G/A cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs11585357 0.793 rs11587669 chr1:17616259 C/T cg08277548 chr1:17600880 PADI3 -0.58 -6.05 -0.31 3.88e-9 Hair shape; LIHC trans rs3783890 1.000 rs12885232 chr14:93771020 T/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.25 0.32 1.24e-9 Body mass index; LIHC cis rs6570726 0.818 rs9390338 chr6:145908265 A/G cg13319975 chr6:146136371 FBXO30 -0.4 -6.31 -0.32 8.87e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7264396 0.561 rs66483315 chr20:34573575 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -8.37 -0.41 1.53e-15 Total cholesterol levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17513182 chr1:153894941 GATAD2B 0.46 6.76 0.34 6.01e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 0.967 rs2149084 chr6:167370988 G/C cg23791538 chr6:167370224 RNASET2 0.69 11.65 0.53 1.22e-26 Crohn's disease; LIHC cis rs1144333 0.655 rs11162053 chr1:76470267 A/C cg10523679 chr1:76189770 ACADM 0.44 6.19 0.32 1.73e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg16405210 chr4:1374714 KIAA1530 -0.54 -7.9 -0.39 3.81e-14 Longevity; LIHC cis rs3790645 1.000 rs282175 chr1:26895802 A/G cg17456097 chr1:26900765 RPS6KA1 0.39 5.83 0.3 1.26e-8 Glucose homeostasis traits; LIHC cis rs57590327 0.679 rs35395999 chr3:81613013 T/C cg07356753 chr3:81810745 GBE1 -0.48 -6.5 -0.33 2.89e-10 Extraversion; LIHC cis rs1707322 0.717 rs2991989 chr1:46082965 C/T cg03146154 chr1:46216737 IPP -0.56 -9.29 -0.45 1.79e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8067354 0.645 rs2173120 chr17:57892640 A/T cg02344993 chr17:57696989 CLTC 0.73 12.38 0.56 2.54e-29 Hemoglobin concentration; LIHC cis rs28374715 0.635 rs8023530 chr15:41647775 T/C cg18705301 chr15:41695430 NDUFAF1 -1.02 -15.06 -0.63 1.13e-39 Ulcerative colitis; LIHC cis rs36051895 0.623 rs1120679 chr9:5248073 C/G cg02405213 chr9:5042618 JAK2 -0.63 -10.38 -0.49 3.95e-22 Pediatric autoimmune diseases; LIHC cis rs2637266 0.655 rs846628 chr10:78538392 G/A cg18941641 chr10:78392320 NA 0.29 6.21 0.32 1.53e-9 Pulmonary function; LIHC cis rs4575098 0.681 rs10797093 chr1:161103445 T/G cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.4 7.4 0.37 1.03e-12 Monocyte percentage of white cells; LIHC trans rs2727020 0.566 rs10839234 chr11:49185524 C/T cg03929089 chr4:120376271 NA -0.79 -14.05 -0.6 1.01e-35 Coronary artery disease; LIHC cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.2e-8 Vitiligo; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18905668 chr11:18388147 GTF2H1 0.41 7.03 0.36 1.16e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4803468 0.967 rs4605279 chr19:41888131 C/G cg09537434 chr19:41945824 ATP5SL -1.0 -20.46 -0.74 2.51e-61 Height; LIHC cis rs597539 0.652 rs501799 chr11:68631240 G/T cg06028808 chr11:68637592 NA 0.42 5.77 0.3 1.76e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs7618501 0.602 rs6780731 chr3:50017478 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.42 0.45 7.2e-19 Intelligence (multi-trait analysis); LIHC cis rs55665837 0.701 rs11023272 chr11:14630370 T/C cg00085434 chr11:14927489 NA 0.43 6.03 0.31 4.36e-9 Vitamin D levels; LIHC cis rs67478160 0.643 rs4900600 chr14:104291839 A/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.56 0.56 4.96e-30 Schizophrenia; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg16103275 chr6:290800 DUSP22 0.51 6.58 0.34 1.81e-10 Menopause (age at onset); LIHC cis rs3008870 1.000 rs7511948 chr1:67430427 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.29 0.66 1.51e-44 Lymphocyte percentage of white cells; LIHC cis rs72781680 0.611 rs4149373 chr2:24300023 C/T cg06627628 chr2:24431161 ITSN2 -0.65 -7.62 -0.38 2.51e-13 Lymphocyte counts; LIHC cis rs2742417 0.603 rs1019129 chr3:45780780 T/C cg04837898 chr3:45731254 SACM1L -0.52 -8.64 -0.42 2.2e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs8180040 0.654 rs9837343 chr3:47177388 C/T cg27129171 chr3:47204927 SETD2 0.57 9.47 0.46 4.9e-19 Colorectal cancer; LIHC cis rs1865760 0.566 rs2794720 chr6:26087202 G/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC cis rs9921222 0.692 rs11860497 chr16:405416 A/G cg26944245 chr16:421049 TMEM8A;MRPL28 0.54 11.29 0.52 2.51e-25 Bone mineral density (spine);Bone mineral density; LIHC cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.62 0.38 2.49e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.98 0.54 7.2e-28 Prudent dietary pattern; LIHC cis rs4718428 0.705 rs62465692 chr7:66295745 T/C cg12165864 chr7:66369176 NA -0.47 -6.82 -0.35 4.17e-11 Corneal structure; LIHC cis rs11252926 0.598 rs4881256 chr10:453831 T/A cg16346588 chr10:242978 ZMYND11 0.38 5.88 0.3 9.83e-9 Psychosis in Alzheimer's disease; LIHC cis rs9534288 0.797 rs7990238 chr13:46578379 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.8 6.24 0.32 1.33e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.565 rs7010503 chr8:58147127 G/A cg21724239 chr8:58056113 NA 0.47 6.23 0.32 1.36e-9 Developmental language disorder (linguistic errors); LIHC cis rs7447593 0.666 rs12659266 chr5:176807197 C/T cg17509989 chr5:176798049 RGS14 0.82 11.51 0.53 4.01e-26 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg17971929 chr21:40555470 PSMG1 0.85 10.53 0.49 1.2e-22 Cognitive function; LIHC cis rs2153535 0.580 rs9406171 chr6:8515362 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs6466055 0.777 rs3779210 chr7:104828098 C/T cg04380332 chr7:105027541 SRPK2 -0.35 -6.68 -0.34 9.74e-11 Schizophrenia; LIHC trans rs208520 0.690 rs1580430 chr6:66715162 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.88 0.43 3.74e-17 Exhaled nitric oxide output; LIHC cis rs12971120 0.891 rs3794955 chr18:72174827 C/T cg26446133 chr18:72167187 CNDP2 -0.8 -14.37 -0.61 5.82e-37 Refractive error; LIHC cis rs67460515 0.563 rs34630898 chr3:160827038 A/G cg17135325 chr3:160939158 NMD3 0.57 8.15 0.4 6.73e-15 Parkinson's disease; LIHC cis rs10771431 1.000 rs10771431 chr12:9380859 C/T cg08997352 chr12:9597637 DDX12 -0.49 -7.27 -0.37 2.5e-12 Breast size; LIHC cis rs3749237 0.595 rs35701831 chr3:49515000 A/C cg07636037 chr3:49044803 WDR6 0.52 8.01 0.4 1.82e-14 Resting heart rate; LIHC cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg27572855 chr1:25598939 RHD -0.38 -8.13 -0.4 7.79e-15 Erythrocyte sedimentation rate; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg00091569 chr3:40428383 ENTPD3 0.38 6.25 0.32 1.2e-9 Renal cell carcinoma; LIHC cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg21522988 chr12:29376872 FAR2 0.3 6.84 0.35 3.59e-11 QT interval; LIHC cis rs12701220 0.817 rs59471534 chr7:1085224 G/A cg26769984 chr7:1090371 C7orf50 0.56 7.49 0.38 6.02e-13 Bronchopulmonary dysplasia; LIHC cis rs1865721 1.000 rs8094181 chr18:73193976 T/A cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.17e-13 Intelligence; LIHC cis rs9614461 0.702 rs3788648 chr22:45727180 G/A cg18180155 chr22:45809454 SMC1B;RIBC2 0.56 6.21 0.32 1.54e-9 Tonsillectomy; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg04234412 chr22:24373322 LOC391322 -0.73 -10.74 -0.5 2.19e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19404433 chr20:21695773 PAX1 0.39 6.19 0.32 1.68e-9 Pancreatic cancer; LIHC cis rs763121 0.853 rs5757141 chr22:38957483 G/A cg06022373 chr22:39101656 GTPBP1 0.67 11.26 0.52 3.25e-25 Menopause (age at onset); LIHC cis rs67311347 0.955 rs6599100 chr3:40447362 C/T cg18306943 chr3:40428807 ENTPD3 0.34 5.77 0.3 1.81e-8 Renal cell carcinoma; LIHC cis rs9916302 0.904 rs68178216 chr17:37526241 A/C cg07936489 chr17:37558343 FBXL20 0.82 12.99 0.57 1.28e-31 Glomerular filtration rate (creatinine); LIHC cis rs17384381 0.953 rs3768223 chr1:85809183 T/C cg16011679 chr1:85725395 C1orf52 0.8 8.26 0.41 3.22e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769765 0.908 rs9616211 chr22:50317676 G/A cg26441486 chr22:50317300 CRELD2 0.38 6.54 0.33 2.31e-10 Schizophrenia; LIHC cis rs4474465 0.920 rs10751291 chr11:78217687 T/C cg27205649 chr11:78285834 NARS2 0.4 6.11 0.31 2.71e-9 Alzheimer's disease (survival time); LIHC cis rs12702595 0.875 rs2108783 chr7:7266867 A/C cg04827551 chr7:7268805 C1GALT1 -0.36 -6.64 -0.34 1.26e-10 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs428668 0.523 rs6898671 chr5:150677643 A/T cg11125805 chr5:150678162 SLC36A3 0.53 12.32 0.55 4.1e-29 Skin aging (microtopography measurement); LIHC cis rs9818758 0.607 rs9990153 chr3:49291883 C/T cg07636037 chr3:49044803 WDR6 -0.74 -7.89 -0.39 4.11e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7772486 0.776 rs2265467 chr6:146218339 T/A cg23711669 chr6:146136114 FBXO30 0.58 10.28 0.49 8.6e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2732480 0.500 rs12829841 chr12:48628739 A/G cg21466736 chr12:48725269 NA -0.7 -10.65 -0.5 4.47e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs2576037 0.501 rs7227700 chr18:44537102 T/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.68 10.8 0.5 1.33e-23 Personality dimensions; LIHC cis rs7487075 0.554 rs7957777 chr12:46628789 A/C cg15584813 chr12:47219626 SLC38A4 0.31 5.72 0.3 2.32e-8 Itch intensity from mosquito bite; LIHC cis rs7959452 0.590 rs11177619 chr12:69758871 G/A cg14784868 chr12:69753453 YEATS4 0.95 20.48 0.74 2.05e-61 Blood protein levels; LIHC cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg03806693 chr22:41940476 POLR3H 1.11 13.05 0.58 7.07e-32 Vitiligo; LIHC cis rs2251381 0.750 rs2251186 chr21:30528880 G/A cg24692254 chr21:30365293 RNF160 0.72 10.26 0.48 1.07e-21 Selective IgA deficiency; LIHC cis rs4555082 0.830 rs3803319 chr14:105752458 G/A cg13114125 chr14:105738426 BRF1 -0.74 -9.78 -0.47 4.42e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs6459788 0.934 rs10237947 chr7:157258109 G/T cg06271696 chr7:157225062 NA 0.39 7.07 0.36 8.62e-12 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs114532231 0.661 rs12617962 chr2:86513102 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.67 6.97 0.35 1.65e-11 Asymmetrical dimethylarginine levels; LIHC cis rs7917772 0.636 rs4919674 chr10:104522226 T/C cg22532475 chr10:104410764 TRIM8 0.36 6.37 0.33 6.16e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11098499 0.955 rs11931312 chr4:120159023 T/C cg09307838 chr4:120376055 NA 0.74 10.9 0.51 6.12e-24 Corneal astigmatism; LIHC cis rs9868809 0.881 rs6773261 chr3:48675064 A/G cg07636037 chr3:49044803 WDR6 -0.55 -6.19 -0.32 1.77e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs2806561 0.729 rs649664 chr1:23324263 C/T cg19743168 chr1:23544995 NA -0.38 -7.06 -0.36 9.22e-12 Height; LIHC cis rs11687659 0.515 rs6725611 chr2:191579025 G/A cg10560079 chr2:191398806 TMEM194B -0.41 -5.72 -0.3 2.35e-8 Immature fraction of reticulocytes; LIHC cis rs6456156 1.000 rs6456156 chr6:167522300 T/C cg07741184 chr6:167504864 NA 0.25 5.96 0.31 6.16e-9 Primary biliary cholangitis; LIHC cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg25072359 chr17:41440525 NA 0.37 5.96 0.31 6.32e-9 Menopause (age at onset); LIHC cis rs713477 0.935 rs10144034 chr14:55914273 C/A cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.45e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10751667 0.666 rs10902248 chr11:957742 A/G cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.09e-12 Alzheimer's disease (late onset); LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg00091569 chr3:40428383 ENTPD3 -0.4 -6.79 -0.34 4.83e-11 Renal cell carcinoma; LIHC cis rs2274273 0.743 rs7161656 chr14:55524530 A/G cg01864836 chr14:55583639 NA -0.38 -6.37 -0.33 6.03e-10 Protein biomarker; LIHC cis rs9916302 0.904 rs8068427 chr17:37511517 G/A cg03013999 chr17:37608204 MED1 -0.34 -5.76 -0.3 1.91e-8 Glomerular filtration rate (creatinine); LIHC cis rs8044995 0.563 rs55968019 chr16:68398111 G/A cg09835421 chr16:68378352 PRMT7 -0.8 -9.62 -0.46 1.46e-19 Schizophrenia; LIHC cis rs651907 0.557 rs11914318 chr3:101453858 C/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.74 -0.3 2.04e-8 Colorectal cancer; LIHC cis rs7677751 0.806 rs4864863 chr4:55100831 A/G cg17187183 chr4:55093834 PDGFRA 0.68 8.49 0.42 6.36e-16 Corneal astigmatism; LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg24209194 chr3:40518798 ZNF619 -0.66 -10.12 -0.48 3.1e-21 Renal cell carcinoma; LIHC cis rs4332037 0.624 rs73046339 chr7:1889300 G/A cg23422044 chr7:1970798 MAD1L1 -0.54 -6.66 -0.34 1.1e-10 Bipolar disorder; LIHC cis rs509477 0.718 rs273342 chr18:32604956 G/A cg23791764 chr18:32556832 MAPRE2 0.45 6.16 0.32 2.08e-9 Cerebrospinal fluid AB1-42 levels; LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg13409248 chr3:40428643 ENTPD3 0.5 8.43 0.41 9.5e-16 Renal cell carcinoma; LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.68 -0.42 1.69e-16 Lymphocyte counts; LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg20399509 chr21:47717575 C21orf57 -0.36 -5.87 -0.3 1.04e-8 Testicular germ cell tumor; LIHC cis rs826838 0.678 rs11182781 chr12:38610178 C/T cg13010199 chr12:38710504 ALG10B 0.58 6.89 0.35 2.62e-11 Heart rate; LIHC cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg00149659 chr3:10157352 C3orf10 0.61 6.71 0.34 7.86e-11 Alzheimer's disease; LIHC cis rs4819052 0.851 rs2838850 chr21:46671445 G/C cg22633049 chr21:46681294 NA -0.37 -6.48 -0.33 3.21e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs807029 0.577 rs3740488 chr10:102754033 A/T cg25179470 chr10:102756915 LZTS2 0.45 6.41 0.33 4.93e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2228479 0.850 rs11076619 chr16:89831243 C/A cg00800038 chr16:89945340 TCF25 -0.61 -8.97 -0.44 1.96e-17 Skin colour saturation; LIHC cis rs10242455 0.850 rs57367781 chr7:99116819 G/A cg18809830 chr7:99032528 PTCD1 -0.83 -6.45 -0.33 3.72e-10 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17562763 chr11:67398026 NUDT8 0.57 7.42 0.37 9.44e-13 Lung function (FEV1/FVC); LIHC trans rs1814175 0.676 rs11040647 chr11:49935947 A/C cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs738322 0.753 rs5756968 chr22:38595240 C/T cg25457927 chr22:38595422 NA 0.43 11.34 0.52 1.6e-25 Cutaneous nevi; LIHC cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg23982607 chr1:1823379 GNB1 -0.66 -13.05 -0.58 7.23e-32 Body mass index; LIHC cis rs9470366 0.545 rs2395655 chr6:36645696 C/T cg08179530 chr6:36648295 CDKN1A -0.76 -13.09 -0.58 4.99e-32 QRS duration; LIHC cis rs17376456 0.877 rs10062711 chr5:93348659 G/A cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.53e-21 Diabetic retinopathy; LIHC cis rs4819052 0.851 rs2838833 chr21:46665160 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.23 0.52 3.93e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs7246657 0.943 rs3760825 chr19:37945601 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs9388451 0.839 rs3799709 chr6:126078361 A/G cg06289844 chr6:126071538 HEY2 0.36 6.44 0.33 3.93e-10 Brugada syndrome; LIHC cis rs986417 1.000 rs7159212 chr14:61068725 T/C cg27398547 chr14:60952738 C14orf39 0.66 6.53 0.33 2.32e-10 Gut microbiota (bacterial taxa); LIHC cis rs62244186 0.516 rs11922470 chr3:44777795 C/T cg25364880 chr3:44379878 C3orf23 0.59 8.13 0.4 7.83e-15 Depressive symptoms; LIHC cis rs9393692 0.840 rs9358915 chr6:26277268 G/A cg13736514 chr6:26305472 NA -0.37 -6.23 -0.32 1.34e-9 Educational attainment; LIHC cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg18305652 chr10:134549665 INPP5A 0.44 6.4 0.33 5.22e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9902453 0.808 rs8069669 chr17:28239502 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 13.53 0.59 1.05e-33 Coffee consumption (cups per day); LIHC cis rs12928939 0.517 rs12445641 chr16:71967783 C/T cg03805757 chr16:71968109 PKD1L3 -0.93 -12.67 -0.57 2.02e-30 Post bronchodilator FEV1; LIHC cis rs892961 0.932 rs66886702 chr17:75412714 G/A cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs6088590 0.735 rs6060003 chr20:33294945 T/C cg08999081 chr20:33150536 PIGU 0.55 9.8 0.47 3.91e-20 Coronary artery disease; LIHC cis rs6912958 0.781 rs9450732 chr6:88249826 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.07 -0.4 1.21e-14 Monocyte percentage of white cells; LIHC cis rs7572733 0.555 rs13395030 chr2:198750806 A/G cg10820045 chr2:198174542 NA 0.47 6.97 0.35 1.6e-11 Dermatomyositis; LIHC cis rs16828019 0.852 rs71648536 chr1:41632008 T/A cg03962019 chr1:41807865 NA 0.53 7.73 0.39 1.25e-13 Intelligence (multi-trait analysis); LIHC cis rs10752881 1.000 rs12028740 chr1:182985581 G/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs4853012 0.941 rs7571083 chr2:74342260 C/G cg19729930 chr2:74357872 NA 0.8 17.31 0.68 1.18e-48 Gestational age at birth (maternal effect); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27120934 chr6:129480619 LAMA2 0.35 6.39 0.33 5.33e-10 Cognitive function; LIHC cis rs2245008 0.762 rs168800 chr16:83980391 T/C cg26931527 chr16:83979911 NA 0.61 5.8 0.3 1.54e-8 Pursuit maintenance gain; LIHC cis rs2576037 0.523 rs4890705 chr18:44509758 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.4 -5.77 -0.3 1.8e-8 Personality dimensions; LIHC cis rs400736 0.637 rs2300428 chr1:7996894 A/G cg25007680 chr1:8021821 PARK7 -0.44 -6.88 -0.35 2.82e-11 Response to antidepressants and depression; LIHC cis rs7572733 0.534 rs1518361 chr2:198812874 A/G cg10820045 chr2:198174542 NA 0.48 7.29 0.37 2.18e-12 Dermatomyositis; LIHC cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg26944245 chr16:421049 TMEM8A;MRPL28 0.42 7.47 0.37 6.8e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs116095464 0.619 rs2303741 chr5:218356 T/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC trans rs875971 0.666 rs13242072 chr7:65765988 A/G cg26939375 chr7:64535504 NA -0.43 -6.63 -0.34 1.3e-10 Aortic root size; LIHC cis rs9616064 0.531 rs867212 chr22:47063330 C/T cg05621596 chr22:47072043 GRAMD4 0.69 10.52 0.49 1.34e-22 Urate levels in obese individuals; LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.19 -0.32 1.72e-9 Total body bone mineral density; LIHC cis rs7224737 1.000 rs11869069 chr17:40287101 C/G cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs8044995 0.563 rs7190134 chr16:68381516 A/G cg09835421 chr16:68378352 PRMT7 0.83 9.8 0.47 3.91e-20 Schizophrenia; LIHC cis rs2235642 0.928 rs2076435 chr16:1607574 C/T cg09025071 chr16:1593152 IFT140;TMEM204 0.32 6.23 0.32 1.37e-9 Coronary artery disease; LIHC cis rs240764 0.853 rs12374612 chr6:100955752 C/T cg09795085 chr6:101329169 ASCC3 -0.44 -5.84 -0.3 1.19e-8 Neuroticism; LIHC cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg03517284 chr6:25882590 NA 0.57 7.82 0.39 6.75e-14 Blood metabolite levels; LIHC cis rs367615 0.512 rs814153 chr5:108667829 A/C cg17395555 chr5:108820864 NA 0.3 6.42 0.33 4.64e-10 Colorectal cancer (SNP x SNP interaction); LIHC cis rs13108904 0.901 rs6851528 chr4:1296009 G/A cg05025164 chr4:1340916 KIAA1530 0.55 8.65 0.42 2.01e-16 Obesity-related traits; LIHC cis rs4906332 1.000 rs35366629 chr14:103903054 A/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.17 -0.32 1.98e-9 Coronary artery disease; LIHC cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg10360323 chr17:41437877 NA 0.4 5.97 0.31 6.06e-9 Menopause (age at onset); LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg24846343 chr22:24311635 DDTL 0.61 11.29 0.52 2.36e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02996314 chr1:32479425 KHDRBS1 0.45 6.36 0.33 6.56e-10 Lung function (FEV1/FVC); LIHC cis rs11146838 1 rs11146838 chr10:39149977 A/T cg18963800 chr10:38644991 HSD17B7P2 -0.46 -6.71 -0.34 7.87e-11 Breast cancer; LIHC cis rs6121246 0.909 rs6060679 chr20:30270772 C/G cg13852791 chr20:30311386 BCL2L1 -0.97 -9.8 -0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs7572733 0.534 rs4850815 chr2:198786167 G/T cg03934865 chr2:198174659 NA -0.46 -6.7 -0.34 8.86e-11 Dermatomyositis; LIHC cis rs34779708 0.931 rs34954932 chr10:35410807 G/T cg03585969 chr10:35415529 CREM 0.86 12.95 0.57 1.73e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.95 8.45 0.42 8.22e-16 Platelet count; LIHC cis rs6963495 0.818 rs56055535 chr7:105163574 C/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs4803468 1.000 rs284663 chr19:41932612 C/T cg14132834 chr19:41945861 ATP5SL -0.46 -6.82 -0.35 4.15e-11 Height; LIHC cis rs72781680 0.898 rs111460347 chr2:24018833 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs2839186 0.843 rs17182671 chr21:47696238 T/C cg00612595 chr21:47717864 NA -0.37 -5.99 -0.31 5.44e-9 Testicular germ cell tumor; LIHC cis rs9611565 0.559 rs7290990 chr22:41964357 C/A cg06634786 chr22:41940651 POLR3H -0.61 -6.53 -0.33 2.39e-10 Vitiligo; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.09 -0.4 1.07e-14 Lymphocyte counts; LIHC cis rs904251 0.797 rs2776878 chr6:37487273 G/A cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.48e-9 Cognitive performance; LIHC cis rs9381040 0.655 rs7775972 chr6:41038116 A/C cg25110423 chr6:41068646 NFYA;LOC221442 -0.35 -5.94 -0.31 6.99e-9 Alzheimer's disease (late onset); LIHC cis rs7647973 1.000 rs4241407 chr3:49600319 C/T cg07636037 chr3:49044803 WDR6 0.54 6.71 0.34 7.89e-11 Menarche (age at onset); LIHC cis rs7917772 0.560 rs4919664 chr10:104363408 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs597539 0.652 rs602805 chr11:68662076 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.93 0.51 4.9e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6547741 0.844 rs55826602 chr2:27863452 A/G cg27432699 chr2:27873401 GPN1 -0.93 -16.28 -0.66 1.63e-44 Oral cavity cancer; LIHC cis rs13108904 0.901 rs7695691 chr4:1304632 A/G cg26570765 chr4:1273065 NA 0.29 5.73 0.3 2.19e-8 Obesity-related traits; LIHC cis rs79149102 0.579 rs76518150 chr15:75292721 C/G cg16226627 chr15:75307476 SCAMP5 0.55 9.62 0.46 1.49e-19 Lung cancer; LIHC cis rs7193541 0.965 rs4402594 chr16:74701360 C/T cg01733217 chr16:74700730 RFWD3 0.52 10.04 0.48 5.86e-21 Multiple myeloma; LIHC cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg17971929 chr21:40555470 PSMG1 0.85 10.18 0.48 1.99e-21 Cognitive function; LIHC cis rs1577917 1.000 rs35797755 chr6:86706554 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.73 -0.34 7.14e-11 Response to antipsychotic treatment; LIHC cis rs2302190 0.882 rs6503859 chr17:56460852 C/G cg12560992 chr17:57184187 TRIM37 0.65 8.2 0.41 4.87e-15 Vitamin D levels; LIHC cis rs903552 1.000 rs8043379 chr15:102005837 A/G cg25677261 chr15:102009856 PCSK6 -0.46 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC cis rs600806 0.778 rs2787015 chr1:110009434 A/C cg11161837 chr1:110010384 SYPL2 0.47 6.35 0.32 6.8e-10 Intelligence (multi-trait analysis); LIHC cis rs477692 0.569 rs7087541 chr10:131309979 A/C cg05714579 chr10:131428358 MGMT 0.41 6.67 0.34 1.01e-10 Response to temozolomide; LIHC cis rs7666738 0.830 rs11722272 chr4:99000839 C/T cg05340658 chr4:99064831 C4orf37 0.69 11.89 0.54 1.58e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02732134 chr10:101732382 DNMBP -0.52 -8.05 -0.4 1.34e-14 Lung function (FEV1/FVC); LIHC cis rs1348850 0.914 rs11893448 chr2:178280013 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.46 0.59 2.05e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7666738 0.962 rs2865985 chr4:99068009 T/C cg05340658 chr4:99064831 C4orf37 0.69 11.66 0.53 1.08e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs6748734 0.948 rs9973334 chr2:241838142 A/G cg09990169 chr2:241835740 C2orf54 -0.71 -11.47 -0.53 5.37e-26 Urinary metabolites; LIHC cis rs11169225 1.000 rs11169225 chr12:50345671 T/A cg04450003 chr12:50355995 AQP5 0.59 7.17 0.36 4.76e-12 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7618501 0.602 rs2013208 chr3:50129399 C/T cg24110177 chr3:50126178 RBM5 0.53 8.54 0.42 4.35e-16 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.591 rs10979613 chr9:111687584 A/G cg05043794 chr9:111880884 C9orf5 -0.23 -5.91 -0.3 8.44e-9 Menarche (age at onset); LIHC cis rs950169 0.519 rs7237 chr15:85186577 C/T cg17507749 chr15:85114479 UBE2QP1 0.61 6.87 0.35 3.12e-11 Schizophrenia; LIHC trans rs2209875 1.000 rs7850776 chr9:91817364 T/C cg26057616 chr1:222234397 NA 0.37 6.18 0.32 1.8e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs903552 0.736 rs9806495 chr15:102008059 G/A cg04789225 chr15:102009795 PCSK6 -0.46 -6.04 -0.31 3.94e-9 Diabetic kidney disease; LIHC cis rs6426558 0.537 rs4653813 chr1:227461510 G/C cg10327440 chr1:227177885 CDC42BPA 0.42 6.42 0.33 4.56e-10 Neutrophil percentage of white cells; LIHC cis rs7208859 0.623 rs9916725 chr17:29107471 A/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3015497 0.653 rs2356456 chr14:51093216 A/T cg09863266 chr14:51125203 SAV1 -0.4 -6.43 -0.33 4.26e-10 Mean platelet volume; LIHC cis rs9534288 0.797 rs9534279 chr13:46584999 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs3806843 1.000 rs4404730 chr5:140162610 G/A cg26395211 chr5:140044315 WDR55 -0.43 -6.35 -0.32 6.88e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6912958 0.967 rs6914299 chr6:88149176 T/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.29 -5.8 -0.3 1.54e-8 Monocyte percentage of white cells; LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg12516959 chr21:47718080 NA -0.37 -5.86 -0.3 1.06e-8 Testicular germ cell tumor; LIHC cis rs1577917 1.000 rs35419329 chr6:86702291 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.59 -0.34 1.66e-10 Response to antipsychotic treatment; LIHC cis rs9300255 0.543 rs1617156 chr12:123590165 T/C cg00376283 chr12:123451042 ABCB9 0.62 8.28 0.41 2.83e-15 Neutrophil percentage of white cells; LIHC cis rs700651 0.789 rs1371663 chr2:198900305 C/T cg00792783 chr2:198669748 PLCL1 -0.45 -6.48 -0.33 3.13e-10 Intracranial aneurysm; LIHC cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.31 -0.45 1.65e-18 Bipolar disorder; LIHC cis rs875971 0.862 rs2909688 chr7:65841612 C/A cg11764359 chr7:65958608 NA 0.78 13.45 0.59 2.21e-33 Aortic root size; LIHC cis rs963731 0.649 rs79361942 chr2:39336315 G/A cg04010122 chr2:39346883 SOS1 0.67 5.99 0.31 5.28e-9 Corticobasal degeneration; LIHC cis rs9443189 0.762 rs2748955 chr6:76464302 C/G cg01950844 chr6:76311363 SENP6 -0.53 -6.39 -0.33 5.34e-10 Prostate cancer; LIHC cis rs2067615 0.579 rs3782709 chr12:107205753 A/G cg15890332 chr12:107067104 RFX4 0.27 6.4 0.33 5.23e-10 Heart rate; LIHC cis rs2933343 0.729 rs1680780 chr3:128612659 G/C cg25356066 chr3:128598488 ACAD9 0.56 7.77 0.39 8.97e-14 IgG glycosylation; LIHC cis rs9543976 1.000 rs2296146 chr13:76143572 T/C cg01531495 chr13:76123901 UCHL3 -0.52 -6.16 -0.32 1.99e-9 Diabetic retinopathy; LIHC cis rs1008375 0.966 rs2098152 chr4:17684392 G/T cg02297831 chr4:17616191 MED28 0.43 6.79 0.34 5.01e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9814567 0.752 rs4955542 chr3:134328740 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs904251 0.523 rs10947675 chr6:37479972 G/A cg08126542 chr6:37504118 NA -0.37 -6.32 -0.32 8.26e-10 Cognitive performance; LIHC cis rs6426558 0.537 rs12139758 chr1:227260519 A/G cg10327440 chr1:227177885 CDC42BPA 0.42 6.43 0.33 4.25e-10 Neutrophil percentage of white cells; LIHC cis rs17854409 1.000 rs6011427 chr20:61496680 C/T cg06598544 chr20:61472147 COL9A3 -0.68 -6.68 -0.34 9.92e-11 Obesity-related traits; LIHC cis rs637571 0.522 rs606978 chr11:65711517 A/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.78 0.43 8.02e-17 Eosinophil percentage of white cells; LIHC cis rs826838 0.967 rs4768329 chr12:39129394 T/C cg26384229 chr12:38710491 ALG10B -0.64 -9.23 -0.45 2.95e-18 Heart rate; LIHC cis rs7072216 0.763 rs2147901 chr10:100165496 A/C cg26618903 chr10:100175079 PYROXD2 0.38 6.11 0.31 2.71e-9 Metabolite levels; LIHC cis rs79387448 0.638 rs74731686 chr2:103043981 G/A cg09003973 chr2:102972529 NA 1.11 9.76 0.47 5.07e-20 Gut microbiota (bacterial taxa); LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg20102877 chr2:27665638 KRTCAP3 -0.41 -5.72 -0.3 2.27e-8 Menopause (age at onset); LIHC cis rs4911259 0.552 rs11700082 chr20:31460244 A/G cg13636640 chr20:31349939 DNMT3B -0.61 -10.68 -0.5 3.47e-23 Inflammatory bowel disease; LIHC cis rs1799949 0.827 rs74252763 chr17:41402020 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.73 0.3 2.25e-8 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11347316 chr11:18343657 GTF2H1;HPS5 0.51 7.22 0.36 3.5e-12 Lung function (FEV1/FVC); LIHC cis rs13118159 0.872 rs4974604 chr4:1345798 T/C cg16405210 chr4:1374714 KIAA1530 -0.58 -7.22 -0.36 3.3e-12 Longevity; LIHC trans rs11098499 0.909 rs6842762 chr4:120398236 A/T cg25214090 chr10:38739885 LOC399744 0.58 9.59 0.46 1.9e-19 Corneal astigmatism; LIHC cis rs155076 1.000 rs261407 chr13:21855213 C/A cg14456004 chr13:21872349 NA -1.13 -12.71 -0.57 1.4e-30 White matter hyperintensity burden; LIHC cis rs4474465 0.850 rs10793326 chr11:78255422 A/C cg27205649 chr11:78285834 NARS2 0.43 6.34 0.32 7.15e-10 Alzheimer's disease (survival time); LIHC cis rs2153535 0.580 rs6597334 chr6:8504779 C/T cg21535247 chr6:8435926 SLC35B3 0.6 7.87 0.39 4.6e-14 Motion sickness; LIHC cis rs12744310 0.887 rs28541673 chr1:41781994 A/G cg03962019 chr1:41807865 NA 0.39 6.23 0.32 1.36e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs61931739 0.500 rs11053066 chr12:34185318 G/A cg26384229 chr12:38710491 ALG10B 0.6 7.67 0.38 1.83e-13 Morning vs. evening chronotype; LIHC cis rs6933660 0.745 rs6912830 chr6:151743629 A/C cg10883421 chr6:151773342 RMND1;C6orf211 0.64 10.78 0.5 1.56e-23 Menarche (age at onset); LIHC cis rs7412746 0.658 rs11204750 chr1:150939744 C/A cg17724175 chr1:150552817 MCL1 0.41 8.05 0.4 1.34e-14 Melanoma; LIHC cis rs7520050 0.966 rs6675946 chr1:46371774 G/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.92 0.3 7.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs12950390 0.853 rs12450729 chr17:45855363 A/G cg03474202 chr17:45855739 NA -0.34 -5.97 -0.31 6.05e-9 IgG glycosylation; LIHC cis rs9311474 0.575 rs4434138 chr3:52556890 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.51 8.86 0.43 4.35e-17 Electroencephalogram traits; LIHC cis rs644148 0.704 rs2686761 chr19:44989752 T/C cg15540054 chr19:45004280 ZNF180 -0.73 -9.98 -0.47 9.57e-21 Personality dimensions; LIHC cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs6570726 0.935 rs384453 chr6:145815145 G/C cg23711669 chr6:146136114 FBXO30 0.55 9.84 0.47 2.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg05564831 chr3:52568323 NT5DC2 0.35 5.86 0.3 1.09e-8 Bipolar disorder; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.72 11.67 0.53 1.03e-26 Prudent dietary pattern; LIHC cis rs2832191 0.791 rs8134407 chr21:30476586 G/A cg24692254 chr21:30365293 RNF160 0.7 12.84 0.57 4.75e-31 Dental caries; LIHC cis rs644799 1.000 rs560854 chr11:95584905 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.88 15.91 0.65 4.72e-43 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3741404 0.560 rs7938819 chr11:63910116 G/A cg18225595 chr11:63971243 STIP1 -0.62 -10.04 -0.48 5.81e-21 Platelet count; LIHC cis rs9788721 0.630 rs77681598 chr15:78906103 C/A cg06917634 chr15:78832804 PSMA4 -0.54 -7.66 -0.38 1.92e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; LIHC cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg18357526 chr6:26021779 HIST1H4A -0.54 -6.63 -0.34 1.3100000000000001e-10 Blood metabolite levels; LIHC cis rs7831492 0.564 rs6981979 chr8:41612255 C/T cg17182837 chr8:41585554 ANK1 -0.27 -6.5 -0.33 2.8e-10 Colorectal cancer; LIHC cis rs35110281 0.782 rs2838329 chr21:45023329 T/C cg21573476 chr21:45109991 RRP1B -0.57 -10.79 -0.5 1.51e-23 Mean corpuscular volume; LIHC cis rs763121 0.853 rs5757211 chr22:39051705 C/T cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC trans rs6598955 0.671 rs7417505 chr1:26575523 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC cis rs9911578 0.967 rs12938821 chr17:56959422 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.676 rs1341603 chr20:34556216 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs11627756 0.915 rs11850368 chr14:103131770 G/C cg12046867 chr14:103022105 NA 0.39 5.93 0.31 7.27e-9 Mean platelet volume; LIHC cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg18357526 chr6:26021779 HIST1H4A 0.58 8.01 0.4 1.85e-14 Blood metabolite levels; LIHC cis rs11792861 1.000 rs11792861 chr9:111809295 A/C cg13535736 chr9:111863775 C9orf5 -0.4 -6.17 -0.32 1.92e-9 Menarche (age at onset); LIHC cis rs921968 0.643 rs13431399 chr2:219469498 G/C cg02176678 chr2:219576539 TTLL4 -0.56 -7.65 -0.38 2.09e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg05564831 chr3:52568323 NT5DC2 0.35 5.73 0.3 2.18e-8 Electroencephalogram traits; LIHC cis rs7769051 1.000 rs9399041 chr6:133096233 T/G cg22852734 chr6:133119734 C6orf192 0.94 9.16 0.44 4.77e-18 Type 2 diabetes nephropathy; LIHC cis rs3806843 1.000 rs7710794 chr5:140209467 T/G cg26395211 chr5:140044315 WDR55 -0.42 -6.2 -0.32 1.63e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs908922 0.676 rs7530609 chr1:152526812 C/A cg20991723 chr1:152506922 NA 0.52 8.81 0.43 6.54e-17 Hair morphology; LIHC cis rs2073300 1.000 rs59283536 chr20:23457575 A/T cg12062639 chr20:23401060 NAPB 0.78 9.7 0.46 8.37e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8072100 0.688 rs12602134 chr17:45582136 C/G cg19378624 chr17:45501242 LOC100272146;C17orf57 0.37 5.78 0.3 1.69e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1949733 0.635 rs4358384 chr4:8536913 C/T cg11789530 chr4:8429930 ACOX3 -0.61 -8.76 -0.43 9.02e-17 Response to antineoplastic agents; LIHC cis rs17253792 0.545 rs71412688 chr14:56021539 A/G cg01858014 chr14:56050164 KTN1 -0.67 -6.11 -0.31 2.74e-9 Putamen volume; LIHC cis rs6952808 0.500 rs3800902 chr7:2144378 C/T cg02951883 chr7:2050386 MAD1L1 -0.65 -10.65 -0.5 4.52e-23 Bipolar disorder and schizophrenia; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg20102877 chr2:27665638 KRTCAP3 -0.43 -5.96 -0.31 6.12e-9 Total body bone mineral density; LIHC cis rs6570726 0.846 rs870491 chr6:145933390 T/G cg23711669 chr6:146136114 FBXO30 0.62 10.58 0.5 8.03e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs2386661 0.826 rs1317516 chr10:5672720 A/G cg17085576 chr10:5658249 NA 0.36 5.82 0.3 1.39e-8 Breast cancer; LIHC cis rs36051895 0.664 rs4593605 chr9:5107278 C/A cg02405213 chr9:5042618 JAK2 -0.67 -11.34 -0.52 1.65e-25 Pediatric autoimmune diseases; LIHC cis rs11792861 0.781 rs72607159 chr9:111764270 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.7 0.43 1.39e-16 Menarche (age at onset); LIHC cis rs2204008 0.806 rs11525001 chr12:38234397 A/G cg26384229 chr12:38710491 ALG10B 0.82 10.46 0.49 2.1e-22 Bladder cancer; LIHC cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg09323728 chr8:95962352 TP53INP1 -0.33 -7.33 -0.37 1.64e-12 Type 2 diabetes; LIHC cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg23978390 chr7:1156363 C7orf50 0.54 7.92 0.39 3.36e-14 Longevity;Endometriosis; LIHC cis rs6445525 0.967 rs2060022 chr3:65999755 A/G cg06109867 chr3:66002991 MAGI1 -0.32 -5.76 -0.3 1.83e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs12980942 0.591 rs3760660 chr19:41769025 A/T cg25627403 chr19:41769009 HNRNPUL1 0.58 7.08 0.36 8.28e-12 Coronary artery disease; LIHC cis rs35306767 0.903 rs12254002 chr10:929133 A/G cg26597838 chr10:835615 NA -1.06 -12.94 -0.57 1.97e-31 Eosinophil percentage of granulocytes; LIHC cis rs2404602 0.669 rs8036703 chr15:76951040 A/G cg03037974 chr15:76606532 NA 0.76 14.82 0.63 1.04e-38 Blood metabolite levels; LIHC trans rs13325613 0.915 rs34677490 chr3:46270748 G/T cg26337592 chr1:153642686 ILF2 0.68 6.18 0.32 1.81e-9 Monocyte count; LIHC cis rs8060686 0.623 rs28700885 chr16:68154544 A/G cg05110241 chr16:68378359 PRMT7 -0.49 -5.96 -0.31 6.44e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs2370759 1.000 rs79578760 chr10:32611264 C/A cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs780096 0.587 rs6743819 chr2:27567407 G/T cg21747090 chr2:27597821 SNX17 -0.47 -7.19 -0.36 4.15e-12 Total body bone mineral density; LIHC trans rs2243480 0.901 rs35256305 chr7:65306405 T/C cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs727505 1.000 rs28844358 chr7:124562695 A/C cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.22e-9 Lewy body disease; LIHC trans rs1499614 0.901 rs2178742 chr7:66197799 G/A cg05590025 chr7:65112418 INTS4L2 -0.58 -6.28 -0.32 1.06e-9 Gout; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg06500355 chr6:111804104 REV3L -0.38 -6.5 -0.33 2.91e-10 Triglycerides; LIHC cis rs1475718 0.526 rs7848481 chr9:137120661 T/C cg21243944 chr9:137118148 NA -0.44 -6.07 -0.31 3.42e-9 Immature fraction of reticulocytes;Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg12310025 chr6:25882481 NA 0.84 11.33 0.52 1.72e-25 Blood metabolite levels; LIHC cis rs10508774 0.810 rs13377150 chr10:32855857 A/G cg01819863 chr10:32635814 EPC1 0.61 5.83 0.3 1.31e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg18219878 chr12:19459468 PLEKHA5 0.41 6.17 0.32 1.89e-9 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg22520471 chr17:61851767 DDX42;CCDC47 -0.48 -7.01 -0.35 1.29e-11 Height; LIHC cis rs11958404 0.615 rs10058832 chr5:157431866 T/A cg05962755 chr5:157440814 NA 0.63 8.24 0.41 3.77e-15 IgG glycosylation; LIHC cis rs2637266 0.745 rs241 chr10:78444456 G/T cg18941641 chr10:78392320 NA 0.27 5.93 0.31 7.36e-9 Pulmonary function; LIHC cis rs796364 0.806 rs11688168 chr2:200916004 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC trans rs75804782 0.521 rs55973123 chr2:239416264 G/A cg01134436 chr17:81009848 B3GNTL1 0.62 6.24 0.32 1.26e-9 Morning vs. evening chronotype;Chronotype; LIHC trans rs8073060 0.586 rs226084 chr17:34019582 T/A cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7216064 1.000 rs8082512 chr17:65837059 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.34 -0.45 1.31e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs314370 0.818 rs12705091 chr7:100472380 C/T cg10426581 chr7:100472382 SRRT 0.53 6.85 0.35 3.43e-11 Resting heart rate; LIHC cis rs10089 1.000 rs1560636 chr5:127447987 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.8 0.35 4.74e-11 Ileal carcinoids; LIHC cis rs9394841 0.692 rs9381097 chr6:41847800 A/G cg17623882 chr6:41773611 USP49 0.44 6.02 0.31 4.48e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs9549328 0.879 rs12428058 chr13:113636504 G/A cg18289306 chr13:113640169 MCF2L 0.43 6.87 0.35 3.05e-11 Systolic blood pressure; LIHC trans rs7874142 0.606 rs10776904 chr9:137689624 C/A cg18109838 chr5:88185987 MEF2C -0.38 -7.48 -0.37 6.52e-13 Longevity; LIHC cis rs1355223 0.583 rs1396880 chr11:34870552 C/T cg11058730 chr11:34937778 PDHX;APIP -0.72 -12.37 -0.56 2.74e-29 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9768139 0.708 rs10262596 chr7:158114495 G/A cg25566285 chr7:158114605 PTPRN2 0.22 6.02 0.31 4.4e-9 Calcium levels; LIHC cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg21448741 chr8:58168803 NA 0.38 6.12 0.31 2.54e-9 Developmental language disorder (linguistic errors); LIHC cis rs12893668 0.572 rs11540512 chr14:104147377 C/T cg24130564 chr14:104152367 KLC1 -0.55 -9.47 -0.46 4.82e-19 Reticulocyte count; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg22907277 chr7:1156413 C7orf50 0.52 8.07 0.4 1.19e-14 Longevity;Endometriosis; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg04234412 chr22:24373322 LOC391322 0.7 10.89 0.51 6.51e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11588062 0.703 rs11589812 chr1:46858748 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.46 7.06 0.36 9.36e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg11764359 chr7:65958608 NA 0.59 5.84 0.3 1.21e-8 Diabetic kidney disease; LIHC cis rs2075165 0.901 rs7542798 chr1:156224304 A/G cg10096929 chr1:156261403 TMEM79 0.35 5.79 0.3 1.56e-8 Tonsillectomy; LIHC cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg20295408 chr7:1910781 MAD1L1 -0.51 -7.31 -0.37 1.96e-12 Bipolar disorder and schizophrenia; LIHC cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg22800045 chr5:56110881 MAP3K1 0.67 8.53 0.42 4.87e-16 Initial pursuit acceleration; LIHC cis rs2228479 0.850 rs11640188 chr16:89807732 C/T cg19635926 chr16:89946313 TCF25 0.49 6.21 0.32 1.5e-9 Skin colour saturation; LIHC cis rs1797081 0.561 rs2603795 chr10:16860256 A/G cg23933602 chr10:16859644 RSU1 0.48 7.18 0.36 4.44e-12 Platelet distribution width; LIHC cis rs12478296 0.681 rs6598999 chr2:242994405 C/A cg06360820 chr2:242988706 NA -0.83 -13.0 -0.57 1.16e-31 Obesity-related traits; LIHC cis rs1005277 0.602 rs1831315 chr10:38473353 T/C cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7.06e-9 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg06873352 chr17:61820015 STRADA 0.73 13.15 0.58 2.92e-32 Prudent dietary pattern; LIHC cis rs12477438 0.798 rs1349778 chr2:99645011 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.53 -0.53 3.3e-26 Chronic sinus infection; LIHC cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.58 0.5 8.39e-23 Total body bone mineral density; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg11618577 chr2:27665543 KRTCAP3 -0.45 -6.22 -0.32 1.49e-9 Total body bone mineral density; LIHC cis rs10463316 0.817 rs906679 chr5:150779302 T/A cg03212797 chr5:150827313 SLC36A1 -0.42 -6.25 -0.32 1.21e-9 Metabolite levels (Pyroglutamine); LIHC cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg13395646 chr4:1353034 KIAA1530 -0.44 -6.98 -0.35 1.55e-11 Obesity-related traits; LIHC cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg04944784 chr2:26401820 FAM59B 0.71 9.3 0.45 1.76e-18 Gut microbiome composition (summer); LIHC cis rs9560113 0.509 rs4773390 chr13:112208904 G/A cg10483660 chr13:112241077 NA 0.25 6.31 0.32 8.63e-10 Menarche (age at onset); LIHC trans rs12620999 0.941 rs2078469 chr2:237983273 C/G cg15676719 chr1:167598521 RCSD1 0.34 6.3 0.32 9.17e-10 Systemic lupus erythematosus; LIHC cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg16497277 chr3:49208875 KLHDC8B -0.49 -5.91 -0.3 8.14e-9 Parkinson's disease; LIHC cis rs853679 0.517 rs1947863 chr6:28099344 G/A cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC trans rs7721647 0.810 rs72771538 chr5:90797727 G/A cg10859192 chr12:54071672 ATP5G2 -0.41 -6.07 -0.31 3.34e-9 Breast cancer; LIHC cis rs6547741 1.000 rs1528402 chr2:27857517 G/A cg27432699 chr2:27873401 GPN1 0.77 12.92 0.57 2.32e-31 Oral cavity cancer; LIHC cis rs7107174 1.000 rs4945268 chr11:78037936 T/C cg02023728 chr11:77925099 USP35 0.5 9.49 0.46 4.03e-19 Testicular germ cell tumor; LIHC cis rs9916302 0.904 rs7221875 chr17:37543328 G/A cg07936489 chr17:37558343 FBXL20 0.84 13.69 0.59 2.64e-34 Glomerular filtration rate (creatinine); LIHC cis rs11233413 0.508 rs10898066 chr11:82680867 A/C cg24227371 chr11:82718527 RAB30 0.3 6.72 0.34 7.42e-11 Economic and political preferences (feminism/equality); LIHC cis rs9560113 1.000 rs9555804 chr13:112179751 T/C cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs763121 0.706 rs3827356 chr22:39064806 G/T cg14440974 chr22:39074834 NA 0.43 7.15 0.36 5.38e-12 Menopause (age at onset); LIHC cis rs875971 1.000 rs11971949 chr7:65626014 A/G cg11764359 chr7:65958608 NA -0.89 -15.52 -0.64 1.66e-41 Aortic root size; LIHC cis rs5769765 0.862 rs9616381 chr22:50312382 G/A cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs7312933 0.966 rs6582375 chr12:42423185 A/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.84 0.35 3.7e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6951245 0.554 rs10270249 chr7:1151886 G/T cg04025307 chr7:1156635 C7orf50 0.62 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2228479 0.850 rs2238527 chr16:89840708 C/A cg00800038 chr16:89945340 TCF25 -0.63 -9.48 -0.46 4.32e-19 Skin colour saturation; LIHC cis rs611744 0.967 rs598022 chr8:109187759 C/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs4332037 0.713 rs56093134 chr7:1973970 C/T cg11693508 chr17:37793320 STARD3 0.73 7.38 0.37 1.23e-12 Bipolar disorder; LIHC cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg21782813 chr7:2030301 MAD1L1 0.44 7.3 0.37 2e-12 Bipolar disorder and schizophrenia; LIHC cis rs7412746 0.634 rs3754212 chr1:150738200 A/G cg18016565 chr1:150552671 MCL1 0.54 10.05 0.48 5.25e-21 Melanoma; LIHC cis rs10089 1.000 rs3805612 chr5:127505316 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.5 6.17 0.32 1.92e-9 Ileal carcinoids; LIHC cis rs12477438 0.520 rs11695379 chr2:99742161 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.88 15.56 0.64 1.2e-41 Chronic sinus infection; LIHC trans rs7777484 0.534 rs2533890 chr7:2828743 C/T cg18070394 chr4:2470786 RNF4 0.39 6.1 0.31 2.92e-9 Height; LIHC cis rs4908768 0.817 rs11587482 chr1:8743195 T/G cg20416874 chr1:8611966 RERE 0.51 7.27 0.37 2.48e-12 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7264396 0.635 rs6058378 chr20:34546658 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.72 -0.5 2.52e-23 Total cholesterol levels; LIHC cis rs17685 0.753 rs2868203 chr7:75680026 G/A cg01364799 chr7:75623366 TMEM120A 0.51 7.81 0.39 6.99e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6089584 0.889 rs6142923 chr20:60596617 C/T cg06108461 chr20:60628389 TAF4 1.0 16.01 0.65 1.95e-43 Body mass index; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg15383120 chr6:291909 DUSP22 -0.48 -6.31 -0.32 8.68e-10 Menopause (age at onset); LIHC cis rs7131987 0.903 rs2194519 chr12:29423583 C/T cg14222432 chr12:29376421 FAR2 -0.38 -7.34 -0.37 1.55e-12 QT interval; LIHC cis rs11758351 0.866 rs55815656 chr6:26207303 G/A cg03785755 chr6:26196794 NA 0.5 5.88 0.3 9.89e-9 Gout;Renal underexcretion gout; LIHC cis rs9420 0.528 rs11229075 chr11:57391023 A/C cg19752551 chr11:57585705 CTNND1 -0.47 -6.04 -0.31 4.02e-9 Schizophrenia; LIHC cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.84 8.59 0.42 3.12e-16 Platelet count; LIHC cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg09904177 chr6:26538194 HMGN4 0.5 9.55 0.46 2.63e-19 Intelligence (multi-trait analysis); LIHC cis rs950169 0.580 rs4603535 chr15:85173872 C/T cg17507749 chr15:85114479 UBE2QP1 0.68 7.77 0.39 9.12e-14 Schizophrenia; LIHC cis rs6582630 0.513 rs1596446 chr12:38282160 C/T cg13010199 chr12:38710504 ALG10B -0.48 -5.79 -0.3 1.63e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs748404 0.660 rs509306 chr15:43715171 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 7.04 0.36 1.06e-11 Lung cancer; LIHC cis rs34779708 0.931 rs11592404 chr10:35273476 G/A cg03585969 chr10:35415529 CREM 0.86 12.96 0.57 1.53e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7937682 0.632 rs11214028 chr11:111761149 T/C cg09085632 chr11:111637200 PPP2R1B 0.93 13.38 0.59 3.93e-33 Primary sclerosing cholangitis; LIHC cis rs2842992 0.662 rs2273826 chr6:160211421 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.14 0.44 5.61e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs7843479 0.601 rs11781959 chr8:21841863 C/G cg17168535 chr8:21777572 XPO7 0.6 10.72 0.5 2.54e-23 Mean corpuscular volume; LIHC cis rs6831352 0.879 rs29001212 chr4:100051877 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs273218 1.000 rs156442 chr5:53373029 T/C ch.5.1024479R chr5:53302184 ARL15 0.67 10.92 0.51 5.1e-24 Migraine; LIHC cis rs9517320 0.934 rs9517319 chr13:99125956 T/G cg07423050 chr13:99094983 FARP1 0.34 5.75 0.3 1.96e-8 Longevity; LIHC cis rs6547741 0.563 rs10196039 chr2:27971195 C/T cg27432699 chr2:27873401 GPN1 -0.81 -13.22 -0.58 1.68e-32 Oral cavity cancer; LIHC cis rs11958404 0.932 rs6859826 chr5:157429710 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.11e-27 IgG glycosylation; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg06558623 chr16:89946397 TCF25 0.95 14.57 0.62 9.87e-38 Skin colour saturation; LIHC cis rs611744 0.967 rs684093 chr8:109199355 G/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs7408868 0.831 rs1548555 chr19:15278057 A/G cg09752223 chr19:15281200 NOTCH3 -0.37 -5.85 -0.3 1.15e-8 Pulse pressure; LIHC trans rs7618501 0.603 rs72942333 chr3:49986118 T/C cg21659725 chr3:3221576 CRBN 0.71 11.58 0.53 2.13e-26 Intelligence (multi-trait analysis); LIHC cis rs17428076 0.793 rs56275355 chr2:172710180 G/A cg13550731 chr2:172543902 DYNC1I2 0.39 6.34 0.32 7.36e-10 Myopia; LIHC cis rs344364 0.511 rs911392 chr16:1947259 A/G cg26897989 chr16:1907736 C16orf73 -0.5 -6.43 -0.33 4.3e-10 Glomerular filtration rate in chronic kidney disease; LIHC cis rs748404 0.631 rs3809482 chr15:43661802 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.81 0.43 6.36e-17 Lung cancer; LIHC cis rs4746818 0.901 rs10740317 chr10:70937566 G/A cg11621586 chr10:70884670 VPS26A 0.83 11.92 0.54 1.27e-27 Left atrial antero-posterior diameter; LIHC cis rs7165170 0.678 rs12593759 chr15:91202601 C/T cg26821196 chr15:91095069 CRTC3 0.39 7.09 0.36 7.85e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7666738 0.570 rs1921415 chr4:99093804 C/T cg05340658 chr4:99064831 C4orf37 0.66 11.63 0.53 1.49e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs10464366 0.519 rs6974609 chr7:39219149 C/T cg10621924 chr7:39171070 POU6F2 0.37 5.81 0.3 1.44e-8 IgG glycosylation; LIHC cis rs11191270 0.554 rs11191274 chr10:104140350 G/A cg15320455 chr10:103880129 LDB1 1.05 7.74 0.39 1.14e-13 Intelligence (multi-trait analysis); LIHC cis rs7116495 1.000 rs10793016 chr11:71755063 A/G cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg00612595 chr21:47717864 NA 0.38 6.24 0.32 1.27e-9 Testicular germ cell tumor; LIHC cis rs2115536 0.606 rs8024713 chr15:80206958 C/G cg00225070 chr15:80189496 MTHFS 0.6 9.54 0.46 2.82e-19 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs9993613 0.967 rs6834847 chr4:73436595 T/G cg15102770 chr4:73434591 ADAMTS3 -0.39 -6.21 -0.32 1.5e-9 Hip circumference adjusted for BMI;Height; LIHC trans rs783540 0.846 rs2099259 chr15:83323688 C/T cg18393722 chr15:85113863 UBE2QP1 0.38 6.49 0.33 2.94e-10 Schizophrenia; LIHC cis rs4631830 0.900 rs4630241 chr10:51532751 G/A cg20129853 chr10:51489980 NA -0.42 -9.1 -0.44 7.71e-18 Prostate-specific antigen levels; LIHC cis rs1552244 0.882 rs3755783 chr3:10029289 A/G cg08888203 chr3:10149979 C3orf24 0.49 6.27 0.32 1.09e-9 Alzheimer's disease; LIHC cis rs311392 0.902 rs438437 chr8:55094187 G/C cg20636351 chr8:55087400 NA -0.37 -7.58 -0.38 3.26e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs7927592 0.913 rs10047412 chr11:68232912 T/C cg16797656 chr11:68205561 LRP5 0.55 8.78 0.43 7.81e-17 Total body bone mineral density; LIHC cis rs17095355 1.000 rs12263915 chr10:111744664 G/C cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.84 -0.3 1.24e-8 Biliary atresia; LIHC trans rs17685 0.712 rs59659102 chr7:75710114 G/A cg19862616 chr7:65841803 NCRNA00174 0.91 18.79 0.71 1.31e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg12310025 chr6:25882481 NA -0.7 -9.09 -0.44 8.25e-18 Intelligence (multi-trait analysis); LIHC cis rs7528419 0.895 rs602633 chr1:109821511 T/G cg00908766 chr1:109817496 CELSR2 0.44 7.67 0.38 1.75e-13 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs3749237 0.636 rs1568662 chr3:49521263 A/G cg07636037 chr3:49044803 WDR6 0.56 8.46 0.42 7.75e-16 Resting heart rate; LIHC cis rs10504073 0.506 rs7007271 chr8:49941897 T/C cg00325661 chr8:49890786 NA 0.34 7.69 0.38 1.61e-13 Blood metabolite ratios; LIHC cis rs1005224 0.853 rs6574251 chr14:76136883 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.41 -5.78 -0.3 1.71e-8 Large artery stroke; LIHC trans rs66573146 0.572 rs66611116 chr4:6953270 A/G cg07817883 chr1:32538562 TMEM39B 1.02 9.01 0.44 1.54e-17 Granulocyte percentage of myeloid white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08555112 chr17:48942811 TOB1 0.46 6.38 0.33 5.68e-10 Pancreatic cancer; LIHC cis rs8060686 0.545 rs12596883 chr16:68172416 A/T cg05110241 chr16:68378359 PRMT7 -0.63 -6.85 -0.35 3.34e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs2204008 0.837 rs11612125 chr12:38213212 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs11588062 0.628 rs3737744 chr1:46810530 C/T cg06787764 chr1:46668870 C1orf190;POMGNT1 -0.46 -7.21 -0.36 3.51e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs13118159 0.934 rs4974553 chr4:1356911 G/A cg16405210 chr4:1374714 KIAA1530 -0.58 -7.25 -0.36 2.89e-12 Longevity; LIHC cis rs9303401 0.555 rs8073699 chr17:57236317 G/A cg12560992 chr17:57184187 TRIM37 0.54 7.38 0.37 1.19e-12 Cognitive test performance; LIHC cis rs9341808 0.529 rs9352826 chr6:81059371 C/T cg08355045 chr6:80787529 NA 0.35 6.98 0.35 1.53e-11 Sitting height ratio; LIHC cis rs11098499 0.615 rs28551750 chr4:120264901 C/T cg09307838 chr4:120376055 NA 0.62 9.75 0.47 5.8e-20 Corneal astigmatism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10668512 chr15:42565522 GANC;TMEM87A 0.45 7.05 0.36 1.01e-11 Cognitive function; LIHC cis rs9733 0.596 rs2867304 chr1:150630995 G/A cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs8081395 0.801 rs12938273 chr17:57901652 G/A cg13753209 chr17:57696993 CLTC -0.48 -7.45 -0.37 7.59e-13 White blood cell count; LIHC cis rs1801251 0.963 rs13011298 chr2:233612996 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.34 0.52 1.59e-25 Coronary artery disease; LIHC trans rs1814175 0.781 rs28681334 chr11:50051177 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.41e-11 Height; LIHC cis rs9911578 0.933 rs11868348 chr17:57179238 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -9.0 -0.44 1.61e-17 Intelligence (multi-trait analysis); LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg25358938 chr8:29940886 TMEM66 -0.56 -6.09 -0.31 3.05e-9 Obesity-related traits; LIHC cis rs1211375 0.606 rs1203977 chr16:256278 A/C cg08400316 chr16:204221 HBZ -0.37 -6.03 -0.31 4.21e-9 Hematology traits;Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1816752 0.905 rs1348110 chr13:24980675 C/T cg22771759 chr13:24902376 NA 0.35 6.67 0.34 1e-10 Obesity-related traits; LIHC cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg09455208 chr3:40491958 NA -0.33 -6.81 -0.35 4.5e-11 Renal cell carcinoma; LIHC cis rs12477438 0.765 rs6740054 chr2:99576631 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.59 -0.38 3.1e-13 Chronic sinus infection; LIHC cis rs67460515 0.892 rs73026974 chr3:160963231 A/C cg03342759 chr3:160939853 NMD3 -0.67 -10.11 -0.48 3.36e-21 Parkinson's disease; LIHC cis rs1691799 0.899 rs903589 chr12:66745835 C/T cg16791601 chr12:66731901 HELB -0.54 -12.93 -0.57 2.05e-31 White blood cell count (basophil); LIHC cis rs6456156 0.586 rs12198816 chr6:167483546 G/A cg12798992 chr6:167411361 FGFR1OP 0.42 6.37 0.33 6.06e-10 Primary biliary cholangitis; LIHC cis rs4919694 0.901 rs79331374 chr10:104882913 G/A cg04362960 chr10:104952993 NT5C2 1.12 8.54 0.42 4.32e-16 Arsenic metabolism; LIHC cis rs7474896 1.000 rs11011339 chr10:37996346 C/A cg25427524 chr10:38739819 LOC399744 -0.5 -6.27 -0.32 1.07e-9 Obesity (extreme); LIHC trans rs637571 0.522 rs649000 chr11:65742933 T/C cg17712092 chr4:129076599 LARP1B 0.74 12.97 0.57 1.44e-31 Eosinophil percentage of white cells; LIHC cis rs7223966 1.000 rs3817181 chr17:61776538 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.59 0.34 1.62e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs918629 0.567 rs4642392 chr5:95255379 A/G cg10483112 chr5:95245456 ELL2 0.37 7.0 0.35 1.34e-11 IgG glycosylation; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg21782813 chr7:2030301 MAD1L1 0.43 7.1 0.36 7.42e-12 Bipolar disorder and schizophrenia; LIHC cis rs9768139 0.596 rs7812034 chr7:158115222 A/G cg06219351 chr7:158114137 PTPRN2 -0.21 -5.86 -0.3 1.09e-8 Calcium levels; LIHC cis rs273218 0.951 rs428213 chr5:53382790 T/G ch.5.1024479R chr5:53302184 ARL15 -0.61 -9.6 -0.46 1.78e-19 Migraine; LIHC cis rs9733 0.544 rs72700902 chr1:150633347 C/T cg18016565 chr1:150552671 MCL1 0.6 11.78 0.54 4.02e-27 Tonsillectomy; LIHC cis rs9486715 0.867 rs2223238 chr6:96871855 G/A cg06623918 chr6:96969491 KIAA0776 0.86 14.94 0.63 3.27e-39 Headache; LIHC cis rs4820294 0.669 rs12628135 chr22:38065655 A/G cg00142150 chr22:38071001 LGALS1 0.43 7.31 0.37 1.95e-12 Fat distribution (HIV); LIHC cis rs778371 0.723 rs2592104 chr2:233645970 G/A cg08000102 chr2:233561755 GIGYF2 0.76 9.47 0.46 4.92e-19 Schizophrenia; LIHC cis rs12477438 0.501 rs7608938 chr2:99782226 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs1712517 0.771 rs11191676 chr10:105155066 C/A cg05636881 chr10:105038444 INA 0.48 7.41 0.37 9.96e-13 Migraine; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06434972 chr7:44122219 POLM 0.46 7.45 0.37 7.54e-13 Cognitive function; LIHC cis rs9325144 0.647 rs870431 chr12:38953073 T/C cg26384229 chr12:38710491 ALG10B -0.46 -6.62 -0.34 1.4e-10 Morning vs. evening chronotype; LIHC cis rs600806 0.888 rs6695482 chr1:109870859 C/G cg16275483 chr1:110013120 SYPL2 -0.5 -6.22 -0.32 1.44e-9 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC trans rs6058796 1.000 rs35220493 chr20:31267831 G/A cg02600331 chr11:130417168 NA 0.36 7.49 0.38 5.93e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs10792665 0.611 rs12277804 chr11:82621549 A/G cg24227371 chr11:82718527 RAB30 -0.28 -6.54 -0.33 2.23e-10 Obesity-related traits; LIHC cis rs929354 0.772 rs1182365 chr7:157017255 A/T cg16102536 chr7:156981717 UBE3C -0.36 -6.14 -0.32 2.25e-9 Body mass index; LIHC cis rs36051895 0.589 rs17492549 chr9:5202830 A/C cg02405213 chr9:5042618 JAK2 -0.61 -9.7 -0.46 8.32e-20 Pediatric autoimmune diseases; LIHC cis rs7395581 0.918 rs1375688 chr11:47327217 G/A cg26139080 chr11:47293733 MADD -0.5 -8.44 -0.42 8.85e-16 HDL cholesterol; LIHC cis rs7959452 0.590 rs10878974 chr12:69781528 C/G cg14784868 chr12:69753453 YEATS4 0.94 20.44 0.74 3.16e-61 Blood protein levels; LIHC cis rs3736485 0.966 rs1031664 chr15:51754897 C/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.38 -0.33 5.75e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11628318 0.614 rs62007925 chr14:103128288 G/A cg23461800 chr14:103021989 NA 0.45 6.31 0.32 8.6e-10 Platelet count; LIHC cis rs7927771 0.524 rs12362318 chr11:47682671 T/C cg20307385 chr11:47447363 PSMC3 0.74 11.19 0.52 5.54e-25 Subjective well-being; LIHC cis rs1348850 0.793 rs6736390 chr2:178480314 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.68 9.19 0.45 3.82e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg21448741 chr8:58168803 NA 0.36 6.59 0.34 1.64e-10 Developmental language disorder (linguistic errors); LIHC cis rs1707322 0.963 rs4660900 chr1:46419605 T/C cg03146154 chr1:46216737 IPP 0.48 7.84 0.39 5.74e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg13047869 chr3:10149882 C3orf24 0.48 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC trans rs116095464 0.558 rs56043030 chr5:220917 A/G cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs950169 0.919 rs12915589 chr15:84734464 T/C cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs1816752 0.905 rs1348110 chr13:24980675 C/T cg02811702 chr13:24901961 NA 0.27 6.38 0.33 5.75e-10 Obesity-related traits; LIHC cis rs2839186 0.584 rs2032111 chr21:47904569 G/A cg12379764 chr21:47803548 PCNT -0.52 -7.42 -0.37 9.07e-13 Testicular germ cell tumor; LIHC cis rs2836950 0.502 rs12627205 chr21:40630027 C/T cg06238570 chr21:40685208 BRWD1 -0.44 -7.11 -0.36 6.81e-12 Menarche (age at onset); LIHC cis rs8180040 0.764 rs2132173 chr3:47247060 C/T cg27129171 chr3:47204927 SETD2 -0.61 -10.46 -0.49 2.16e-22 Colorectal cancer; LIHC cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg13395646 chr4:1353034 KIAA1530 -0.43 -6.4 -0.33 5.06e-10 Longevity; LIHC cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.69 -11.51 -0.53 3.96e-26 Colorectal cancer; LIHC cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.26e-9 Menopause (age at onset); LIHC cis rs2019216 0.502 rs1842113 chr17:21872137 G/A cg22648282 chr17:21454238 C17orf51 -0.44 -7.25 -0.37 2.74e-12 Pelvic organ prolapse; LIHC cis rs7119 0.717 rs11629835 chr15:77787469 G/T cg17802220 chr15:77601643 NA -0.41 -6.96 -0.35 1.73e-11 Type 2 diabetes; LIHC cis rs72781680 1.000 rs72781643 chr2:24208746 G/A cg08917208 chr2:24149416 ATAD2B 0.81 7.44 0.37 8.45e-13 Lymphocyte counts; LIHC cis rs892961 0.899 rs8071024 chr17:75414067 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.44 0.37 8.37e-13 Airflow obstruction; LIHC cis rs972578 0.967 rs6002985 chr22:43333427 C/T cg01576275 chr22:43409880 NA -0.33 -5.77 -0.3 1.75e-8 Mean platelet volume; LIHC cis rs1348850 0.793 rs13020788 chr2:178480714 C/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.65 8.98 0.44 1.86e-17 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10751667 0.714 rs7396700 chr11:963863 A/C cg10932868 chr11:921992 NA 0.4 7.48 0.38 6.23e-13 Alzheimer's disease (late onset); LIHC cis rs7726839 0.526 rs11960158 chr5:568665 C/T cg09021430 chr5:549028 NA -0.42 -8.82 -0.43 5.96e-17 Obesity-related traits; LIHC cis rs17685 0.753 rs10085567 chr7:75734206 A/C cg04610667 chr7:75704037 NA -0.33 -5.85 -0.3 1.16e-8 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs769267 0.965 rs2074299 chr19:19380646 T/C cg03709012 chr19:19516395 GATAD2A 0.94 15.44 0.64 3.51e-41 Tonsillectomy; LIHC cis rs769267 0.895 rs2905435 chr19:19495954 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 -0.39 -5.87 -0.3 1.03e-8 Tonsillectomy; LIHC cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg27297192 chr10:134578999 INPP5A 0.53 7.42 0.37 9.64e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg23283495 chr1:209979779 IRF6 0.46 7.38 0.37 1.24e-12 Cleft lip with or without cleft palate; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg07148452 chr15:90176987 KIF7 0.46 6.59 0.34 1.63e-10 Bilirubin levels; LIHC cis rs10744422 0.858 rs7980541 chr12:123379477 C/T cg07706471 chr12:123319906 HIP1R -0.59 -7.74 -0.39 1.13e-13 Schizophrenia; LIHC cis rs2573652 0.722 rs12914189 chr15:100544429 A/T cg09918751 chr15:100517450 ADAMTS17 0.69 12.01 0.54 5.91e-28 Height; LIHC cis rs12477438 0.520 rs2632277 chr2:99778985 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.83 14.86 0.63 6.96e-39 Chronic sinus infection; LIHC cis rs10751667 0.600 rs1128413 chr11:1010694 C/T cg06064525 chr11:970664 AP2A2 -0.44 -10.72 -0.5 2.54e-23 Alzheimer's disease (late onset); LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg02990361 chr1:107599529 PRMT6 -0.59 -9.56 -0.46 2.42e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17309827 0.965 rs13206690 chr6:3433340 T/G cg00476032 chr6:3446245 SLC22A23 -0.32 -5.81 -0.3 1.45e-8 Crohn's disease; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg16132339 chr22:24313637 DDTL;DDT -0.65 -11.61 -0.53 1.7e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8005677 1.000 rs1956880 chr14:23394007 A/G cg25600027 chr14:23388339 RBM23 -0.43 -6.21 -0.32 1.57e-9 Cognitive ability (multi-trait analysis); LIHC cis rs1494950 1.000 rs28520420 chr4:15007619 C/T cg12377275 chr4:15005593 CPEB2 -0.84 -7.53 -0.38 4.59e-13 Political ideology; LIHC cis rs72781680 1.000 rs17712391 chr2:24245659 C/T cg08917208 chr2:24149416 ATAD2B 0.82 6.36 0.33 6.5e-10 Lymphocyte counts; LIHC cis rs8067354 0.645 rs2665400 chr17:57880201 G/A cg02344993 chr17:57696989 CLTC 0.7 11.92 0.54 1.26e-27 Hemoglobin concentration; LIHC cis rs9902453 0.791 rs7219163 chr17:28210703 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 14.0 0.6 1.67e-35 Coffee consumption (cups per day); LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg05484376 chr2:27715224 FNDC4 0.38 6.44 0.33 4.11e-10 Total body bone mineral density; LIHC trans rs875971 0.638 rs801216 chr7:66011667 T/C cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12963096 chr13:39612675 NHLRC3;C13orf23 0.53 7.42 0.37 9.6e-13 Lung function (FEV1/FVC); LIHC trans rs1552244 0.572 rs73117481 chr3:10160132 C/T cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs477692 0.875 rs7091540 chr10:131420276 C/T cg19680672 chr10:131412579 MGMT 0.42 6.53 0.33 2.39e-10 Response to temozolomide; LIHC cis rs4908760 0.827 rs7556169 chr1:8741401 C/T cg20416874 chr1:8611966 RERE 0.67 14.11 0.61 6.18e-36 Vitiligo; LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg02816363 chr19:55963123 NA 0.43 6.14 0.32 2.29e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs787274 0.619 rs10115576 chr9:115617822 T/C cg13803584 chr9:115635662 SNX30 -0.57 -6.29 -0.32 9.68e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs876084 0.505 rs4871044 chr8:121158773 C/T cg06265175 chr8:121136014 COL14A1 0.42 6.58 0.34 1.8e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07951810 chr12:65153561 GNS 0.5 7.3 0.37 2.05e-12 Cognitive function; LIHC cis rs2370759 1.000 rs2370759 chr10:32634972 G/A cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg02581963 chr10:102133317 C10orf75 -0.42 -6.93 -0.35 2.15e-11 Metabolic traits; LIHC cis rs933688 1.000 rs4382199 chr5:90744228 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.25 0.66 2.13e-44 Smoking behavior; LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg07133347 chr1:107600762 PRMT6 0.46 6.83 0.35 3.87e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1113500 1.000 rs1777483 chr1:108609408 A/C cg06207961 chr1:108661230 NA -0.35 -6.88 -0.35 2.82e-11 Growth-regulated protein alpha levels; LIHC cis rs4927850 0.521 rs4927679 chr3:195658360 C/T cg22809023 chr3:195622598 TNK2 -0.43 -6.41 -0.33 4.75e-10 Pancreatic cancer; LIHC cis rs919433 0.963 rs10199410 chr2:198155776 A/T cg10820045 chr2:198174542 NA -0.61 -10.38 -0.49 4.04e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10779751 0.734 rs2486920 chr1:11125050 T/C cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg24846343 chr22:24311635 DDTL 0.64 12.21 0.55 1.03e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs870825 0.616 rs745656 chr4:185637523 C/T cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC trans rs8002861 0.967 rs7983109 chr13:44484351 C/A cg17145862 chr1:211918768 LPGAT1 0.67 13.33 0.58 6e-33 Leprosy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27454894 chr16:88878596 APRT 0.46 6.77 0.34 5.61e-11 Lung function (FEV1/FVC); LIHC cis rs2243480 0.522 rs73150635 chr7:65972490 C/T cg12463550 chr7:65579703 CRCP 0.72 6.85 0.35 3.35e-11 Diabetic kidney disease; LIHC cis rs1982963 0.627 rs77101097 chr14:52494300 C/T cg10843707 chr14:52510701 NID2 0.37 5.98 0.31 5.77e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs3011225 0.710 rs3011224 chr1:44318483 C/T cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Amyotrophic lateral sclerosis (age of onset); LIHC cis rs1506636 0.962 rs2456551 chr7:123394610 C/G cg03229431 chr7:123269106 ASB15 0.6 12.04 0.55 4.52e-28 Plateletcrit;Platelet count; LIHC cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg22800045 chr5:56110881 MAP3K1 -0.65 -8.3 -0.41 2.48e-15 Initial pursuit acceleration; LIHC cis rs2576037 0.583 rs644731 chr18:44426877 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.88 -0.3 9.96e-9 Personality dimensions; LIHC cis rs10106298 0.904 rs7835270 chr8:103668320 A/G cg10187029 chr8:103597600 NA 0.53 6.79 0.34 4.93e-11 Schizophrenia; LIHC cis rs7927592 0.913 rs12285993 chr11:68302538 A/G cg16797656 chr11:68205561 LRP5 0.51 8.1 0.4 9.54e-15 Total body bone mineral density; LIHC cis rs2576037 0.526 rs7234570 chr18:44459656 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.56 0.5 9.43e-23 Personality dimensions; LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg07133347 chr1:107600762 PRMT6 -0.45 -6.73 -0.34 7.27e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.98 0.54 7.38e-28 Prudent dietary pattern; LIHC cis rs6540556 0.723 rs9430014 chr1:209905372 A/C cg05527609 chr1:210001259 C1orf107 -0.58 -7.83 -0.39 6.22e-14 Red blood cell count; LIHC cis rs6598955 0.670 rs6663950 chr1:26560131 T/C cg04990556 chr1:26633338 UBXN11 -0.62 -10.32 -0.49 6.59e-22 Obesity-related traits; LIHC cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg02290350 chr8:58132656 NA 0.49 9.23 0.45 2.88e-18 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.883 rs529529 chr11:111461128 C/T cg09085632 chr11:111637200 PPP2R1B -0.91 -11.02 -0.51 2.32e-24 Primary sclerosing cholangitis; LIHC cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg07308232 chr7:1071921 C7orf50 -0.56 -9.22 -0.45 3.17e-18 Longevity;Endometriosis; LIHC cis rs875971 0.545 rs3936065 chr7:65790564 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.24 0.36 3.03e-12 Aortic root size; LIHC cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg13397359 chr6:42928475 GNMT 0.76 11.22 0.52 4.41e-25 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3796619 0.503 rs13147452 chr4:1078124 G/A cg27284194 chr4:1044797 NA 0.78 14.59 0.62 8.18e-38 Recombination rate (males); LIHC cis rs875971 0.545 rs316305 chr7:65617971 G/A cg11764359 chr7:65958608 NA -0.51 -7.08 -0.36 8.1e-12 Aortic root size; LIHC cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg13395646 chr4:1353034 KIAA1530 0.4 6.39 0.33 5.42e-10 Obesity-related traits; LIHC cis rs1401999 1.000 rs4148579 chr3:183685249 T/C cg05044414 chr3:183734942 ABCC5 0.35 6.15 0.32 2.2e-9 Anterior chamber depth; LIHC trans rs1005277 0.579 rs1780121 chr10:38529437 C/A cg17830980 chr10:43048298 ZNF37B -0.52 -9.97 -0.47 1.01e-20 Extrinsic epigenetic age acceleration; LIHC cis rs12477438 0.520 rs6542869 chr2:99783403 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.49 0.64 2.17e-41 Chronic sinus infection; LIHC cis rs7927771 0.864 rs3781625 chr11:47443080 T/C cg20307385 chr11:47447363 PSMC3 -0.46 -6.0 -0.31 5.1e-9 Subjective well-being; LIHC trans rs916888 0.821 rs199525 chr17:44847834 T/G cg22968622 chr17:43663579 NA 1.2 12.94 0.57 1.93e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs9929218 0.507 rs62057805 chr16:68742390 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.85 18.26 0.7 1.79e-52 Colorectal cancer; LIHC cis rs7945705 0.774 rs6486060 chr11:9024630 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.47 7.95 0.39 2.76e-14 Hemoglobin concentration; LIHC cis rs8060686 0.623 rs6499162 chr16:68239460 T/C cg05110241 chr16:68378359 PRMT7 -0.49 -5.88 -0.3 9.56e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs1580019 0.587 rs1597555 chr7:32546118 T/G cg14728415 chr7:32535168 LSM5;AVL9 0.42 6.04 0.31 3.96e-9 Cognitive ability; LIHC cis rs1799949 0.965 rs799910 chr17:41279561 G/C cg23758822 chr17:41437982 NA 0.95 17.96 0.7 2.95e-51 Menopause (age at onset); LIHC cis rs1707322 0.656 rs2991981 chr1:46057144 A/G cg06784218 chr1:46089804 CCDC17 -0.4 -7.12 -0.36 6.4e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs854765 0.647 rs854770 chr17:18019048 A/G cg04398451 chr17:18023971 MYO15A -0.75 -13.29 -0.58 9.19e-33 Total body bone mineral density; LIHC trans rs1005277 0.540 rs4934907 chr10:38015230 A/C cg27523141 chr10:43048294 ZNF37B 0.4 7.01 0.35 1.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs9902453 0.967 rs12450956 chr17:28529025 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.57 8.71 0.43 1.28e-16 Coffee consumption (cups per day); LIHC cis rs11711311 0.955 rs9830102 chr3:113408302 C/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.42 7.61 0.38 2.62e-13 IgG glycosylation; LIHC cis rs11719291 0.833 rs11713694 chr3:48833615 G/T cg00383909 chr3:49044727 WDR6 0.92 7.72 0.39 1.26e-13 Cognitive function; LIHC cis rs36051895 0.589 rs11790596 chr9:5198335 T/C cg02405213 chr9:5042618 JAK2 -0.71 -12.19 -0.55 1.2e-28 Pediatric autoimmune diseases; LIHC trans rs783540 1.000 rs698500 chr15:83237769 T/C cg18393722 chr15:85113863 UBE2QP1 -0.4 -7.05 -0.36 1.02e-11 Schizophrenia; LIHC cis rs1062177 1.000 rs62377945 chr5:151208004 C/G cg00977110 chr5:151150581 G3BP1 0.52 6.54 0.33 2.3e-10 Preschool internalizing problems; LIHC cis rs16866061 1.000 rs72974203 chr2:225408430 G/A cg12698349 chr2:225449008 CUL3 0.81 14.11 0.61 5.84e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs7772486 0.846 rs1474871 chr6:146406294 G/A cg23711669 chr6:146136114 FBXO30 0.58 10.1 0.48 3.54e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs10540 1.000 rs12419716 chr11:503385 C/G cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.78e-15 Body mass index; LIHC cis rs6500602 0.789 rs2404546 chr16:4479734 C/G cg08645402 chr16:4508243 NA 0.37 7.0 0.35 1.34e-11 Schizophrenia; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg11494091 chr17:61959527 GH2 0.46 8.29 0.41 2.55e-15 Prudent dietary pattern; LIHC cis rs72781680 0.898 rs72786270 chr2:24059049 G/A cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs2075165 0.901 rs7522860 chr1:156275281 C/T cg21003380 chr1:156261207 TMEM79 0.34 5.76 0.3 1.93e-8 Tonsillectomy; LIHC cis rs6938 0.618 rs11072514 chr15:75221865 T/A cg14664628 chr15:75095509 CSK -0.47 -5.86 -0.3 1.09e-8 Breast cancer; LIHC cis rs5769765 0.954 rs910799 chr22:50278568 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.76 9.8 0.47 3.86e-20 Schizophrenia; LIHC trans rs12753920 0.642 rs7533077 chr1:92584519 C/T cg15668468 chr10:118892869 VAX1 -0.41 -6.07 -0.31 3.48e-9 Systemic lupus erythematosus; LIHC trans rs916888 0.647 rs199449 chr17:44808902 G/A cg22968622 chr17:43663579 NA 0.49 7.15 0.36 5.16e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg07061783 chr6:25882402 NA -0.74 -9.28 -0.45 2.03e-18 Intelligence (multi-trait analysis); LIHC cis rs4819852 1.000 rs1034566 chr22:19984277 C/T cg07821417 chr22:19972146 ARVCF 0.44 5.79 0.3 1.56e-8 Pulse pressure; LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg12016809 chr21:47604291 C21orf56 -0.48 -7.44 -0.37 8.36e-13 Testicular germ cell tumor; LIHC cis rs2242116 1.000 rs2242116 chr3:46941116 A/G cg02527881 chr3:46936655 PTH1R -0.52 -10.94 -0.51 4.52e-24 Birth weight; LIHC cis rs7178375 1.000 rs1474382 chr15:31214649 A/G cg19680485 chr15:31195859 MTMR15 -0.56 -6.01 -0.31 4.83e-9 Hypertriglyceridemia; LIHC cis rs6456156 0.846 rs204293 chr6:167514481 T/C cg23791538 chr6:167370224 RNASET2 -0.39 -6.19 -0.32 1.73e-9 Primary biliary cholangitis; LIHC cis rs875971 0.545 rs6961853 chr7:66002022 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 7.0 0.35 1.34e-11 Aortic root size; LIHC cis rs1005277 0.579 rs2472178 chr10:38384750 T/C cg25427524 chr10:38739819 LOC399744 -0.68 -13.35 -0.59 5.14e-33 Extrinsic epigenetic age acceleration; LIHC cis rs5769765 0.913 rs4824111 chr22:50284305 A/G cg09182678 chr22:50328711 NA 0.43 6.16 0.32 2.04e-9 Schizophrenia; LIHC cis rs7944584 0.655 rs2856653 chr11:47361084 T/C cg20307385 chr11:47447363 PSMC3 -0.54 -5.85 -0.3 1.18e-8 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs8081395 0.834 rs2665397 chr17:57826731 C/A cg02344993 chr17:57696989 CLTC -0.45 -7.29 -0.37 2.22e-12 White blood cell count; LIHC cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg12292205 chr6:26970375 C6orf41 -0.47 -8.12 -0.4 8.73e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs10792665 0.640 rs2086298 chr11:82619218 C/T cg24227371 chr11:82718527 RAB30 -0.27 -6.09 -0.31 3.09e-9 Obesity-related traits; LIHC cis rs3806843 1.000 rs6898906 chr5:140169299 C/G cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9911578 0.935 rs12948039 chr17:57045184 C/T cg05425664 chr17:57184151 TRIM37 -0.55 -8.24 -0.41 3.69e-15 Intelligence (multi-trait analysis); LIHC cis rs4820539 0.966 rs3788350 chr22:23468468 C/T cg14186256 chr22:23484241 RTDR1 0.94 19.09 0.72 7.75e-56 Bone mineral density; LIHC cis rs3981351 0.797 rs61866461 chr10:115454862 C/A cg24846397 chr10:115438155 CASP7 -0.45 -6.84 -0.35 3.65e-11 Obesity-related traits; LIHC trans rs116095464 0.558 rs10057492 chr5:239503 T/C cg00938859 chr5:1591904 SDHAP3 0.58 7.11 0.36 7.03e-12 Breast cancer; LIHC cis rs8072100 0.967 rs4580230 chr17:45738861 G/A cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.36 -5.86 -0.3 1.1e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg18252515 chr7:66147081 NA -1.24 -15.85 -0.65 7.92e-43 Diabetic kidney disease; LIHC cis rs6733011 0.578 rs12712038 chr2:99497710 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.45 -6.46 -0.33 3.52e-10 Bipolar disorder; LIHC cis rs1008375 0.931 rs6813374 chr4:17649494 T/C cg02297831 chr4:17616191 MED28 0.5 7.8 0.39 7.38e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12908161 1.000 rs12911736 chr15:85240008 A/G cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.77e-11 Schizophrenia; LIHC cis rs9902453 0.933 rs2054846 chr17:28507693 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.58 -8.76 -0.43 9.19e-17 Coffee consumption (cups per day); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03359468 chr8:26240463 BNIP3L -0.56 -6.56 -0.33 1.98e-10 Systolic blood pressure; LIHC cis rs2292096 1.000 rs16830092 chr1:200823498 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -6.12 -0.31 2.61e-9 Epilepsy; LIHC cis rs8141529 0.673 rs132548 chr22:29317559 C/G cg15103426 chr22:29168792 CCDC117 -0.56 -9.11 -0.44 6.87e-18 Lymphocyte counts; LIHC cis rs28374715 0.578 rs72739630 chr15:41631064 G/A cg18705301 chr15:41695430 NDUFAF1 -1.24 -17.0 -0.68 2.02e-47 Ulcerative colitis; LIHC trans rs10411161 0.702 rs8110531 chr19:52383510 C/T cg22319618 chr22:45562946 NUP50 -0.6 -8.08 -0.4 1.13e-14 Breast cancer; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs7829975 0.514 rs2976929 chr8:8258712 T/C cg08975724 chr8:8085496 FLJ10661 0.37 6.17 0.32 1.91e-9 Mood instability; LIHC cis rs10791097 0.629 rs11222361 chr11:130731424 T/G cg12179176 chr11:130786555 SNX19 0.73 11.66 0.53 1.11e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg15691649 chr6:25882328 NA -0.54 -7.9 -0.39 3.82e-14 Blood metabolite levels; LIHC cis rs7927771 0.524 rs7101597 chr11:47797917 A/T cg20307385 chr11:47447363 PSMC3 0.72 10.68 0.5 3.75e-23 Subjective well-being; LIHC cis rs9733 0.744 rs2089081 chr1:150800117 T/C cg18016565 chr1:150552671 MCL1 -0.49 -9.73 -0.47 6.75e-20 Tonsillectomy; LIHC cis rs7223966 0.921 rs7225092 chr17:61864005 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.68 0.34 9.88e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs35146811 0.961 rs35991721 chr7:99728790 G/T cg13334819 chr7:99746414 C7orf59 -0.6 -8.56 -0.42 4e-16 Coronary artery disease; LIHC cis rs7412746 0.587 rs11204722 chr1:150730184 A/C cg18016565 chr1:150552671 MCL1 -0.54 -10.52 -0.49 1.32e-22 Melanoma; LIHC trans rs1814175 0.533 rs4528310 chr11:49983106 C/A cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs7918232 0.830 rs9833 chr10:27400861 G/A cg14240646 chr10:27532245 ACBD5 -0.69 -6.4 -0.33 5.12e-10 Breast cancer; LIHC cis rs6942756 0.806 rs2718093 chr7:128939582 G/A cg02491457 chr7:128862824 NA -0.56 -8.29 -0.41 2.55e-15 White matter hyperintensity burden; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg21747090 chr2:27597821 SNX17 -0.41 -6.02 -0.31 4.53e-9 Total body bone mineral density; LIHC cis rs1385374 0.858 rs10847692 chr12:129289679 A/T cg09035930 chr12:129282057 SLC15A4 -0.5 -5.96 -0.31 6.13e-9 Systemic lupus erythematosus; LIHC cis rs1707322 0.752 rs11211169 chr1:46166709 A/G cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7917772 0.503 rs7915589 chr10:104299264 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.05 0.58 7.17e-32 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg10802521 chr3:52805072 NEK4 -0.44 -7.22 -0.36 3.42e-12 Bipolar disorder; LIHC cis rs9303401 0.659 rs35928756 chr17:56702652 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg23205692 chr1:25664452 TMEM50A 0.41 6.78 0.34 5.45e-11 Erythrocyte sedimentation rate; LIHC cis rs4555082 0.874 rs2245329 chr14:105719181 T/C cg06808227 chr14:105710500 BRF1 -0.62 -8.45 -0.42 8.54e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs4243830 0.737 rs7552172 chr1:6612269 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.85 -10.88 -0.51 7.02e-24 Body mass index; LIHC cis rs752092 1.000 rs7182945 chr15:101784223 C/T cg25114630 chr15:101792522 CHSY1 0.55 6.95 0.35 1.81e-11 Corneal structure; LIHC cis rs7107174 0.901 rs11237459 chr11:78056273 A/C cg02023728 chr11:77925099 USP35 0.41 7.77 0.39 9.21e-14 Testicular germ cell tumor; LIHC cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4654899 0.680 rs12407731 chr1:21254789 C/T cg08539965 chr1:21396338 EIF4G3 0.34 6.0 0.31 5.13e-9 Superior frontal gyrus grey matter volume; LIHC cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 12.53 0.56 6.63e-30 Platelet count; LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg20887711 chr4:1340912 KIAA1530 0.76 12.03 0.55 4.98e-28 Longevity; LIHC cis rs11628318 0.614 rs1190337 chr14:103106159 A/C cg12046867 chr14:103022105 NA -0.47 -6.78 -0.34 5.25e-11 Platelet count; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.85e-11 Prudent dietary pattern; LIHC cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.87 8.14 0.4 7.21e-15 Platelet count; LIHC cis rs4908768 0.657 rs4908510 chr1:8806345 C/G cg20416874 chr1:8611966 RERE -0.45 -6.93 -0.35 2.1e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs67311347 0.911 rs6776044 chr3:40377503 T/G cg09455208 chr3:40491958 NA 0.33 6.51 0.33 2.63e-10 Renal cell carcinoma; LIHC cis rs6951245 0.554 rs11544331 chr7:1131411 C/T cg04025307 chr7:1156635 C7orf50 0.66 6.54 0.33 2.22e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs763014 1.000 rs763014 chr16:675680 T/C cg00802000 chr16:706648 WDR90 -0.38 -6.22 -0.32 1.49e-9 Height; LIHC cis rs831571 0.703 rs831566 chr3:64075938 G/T cg16258503 chr3:63850278 ATXN7;THOC7 0.51 6.43 0.33 4.31e-10 Type 2 diabetes; LIHC cis rs9399135 0.935 rs9376086 chr6:135371329 T/C cg24558204 chr6:135376177 HBS1L 0.44 7.23 0.36 3.16e-12 Red blood cell count; LIHC cis rs72781680 0.611 rs72783619 chr2:24311607 G/A cg06627628 chr2:24431161 ITSN2 -0.65 -7.54 -0.38 4.39e-13 Lymphocyte counts; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg04234412 chr22:24373322 LOC391322 -0.94 -16.17 -0.66 4.57e-44 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs477692 1.000 rs479478 chr10:131428959 G/A cg19680672 chr10:131412579 MGMT -0.47 -7.23 -0.36 3.18e-12 Response to temozolomide; LIHC cis rs6964587 1.000 rs35317449 chr7:91637010 G/A cg17063962 chr7:91808500 NA 1.0 19.11 0.72 6.53e-56 Breast cancer; LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.69 0.62 3.3e-38 Prudent dietary pattern; LIHC cis rs6952808 0.601 rs3800882 chr7:2120758 G/A cg21782813 chr7:2030301 MAD1L1 0.34 5.84 0.3 1.25e-8 Bipolar disorder and schizophrenia; LIHC cis rs3936840 0.539 rs11850701 chr14:102983857 G/A cg10241871 chr14:102965420 TECPR2 -0.5 -7.86 -0.39 5.1e-14 Plateletcrit; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg13627451 chr15:52043674 TMOD2;LYSMD2 -0.43 -6.09 -0.31 3.08e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs2439831 0.850 rs3862142 chr15:44064806 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.43 0.33 4.32e-10 Lung cancer in ever smokers; LIHC cis rs10792665 0.512 rs4280021 chr11:82582563 C/T cg24227371 chr11:82718527 RAB30 -0.27 -6.56 -0.33 1.96e-10 Obesity-related traits; LIHC cis rs2637266 0.626 rs724113 chr10:78557309 C/T cg18941641 chr10:78392320 NA 0.3 6.46 0.33 3.58e-10 Pulmonary function; LIHC cis rs1163251 0.902 rs639216 chr1:120217414 C/T cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC cis rs1670533 0.932 rs13140571 chr4:1054358 T/C cg27284194 chr4:1044797 NA 0.6 8.93 0.43 2.6e-17 Recombination rate (females); LIHC cis rs17685 0.523 rs10246583 chr7:75746667 C/A cg01364799 chr7:75623366 TMEM120A -0.48 -7.2 -0.36 3.79e-12 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg11700415 chr19:49140818 SEC1;DBP -0.38 -6.08 -0.31 3.13e-9 Eotaxin levels; LIHC cis rs5753618 0.539 rs737888 chr22:31611549 A/G cg22777020 chr22:31556080 RNF185 -0.55 -6.24 -0.32 1.26e-9 Colorectal cancer; LIHC cis rs933688 1.000 rs12654787 chr5:90713259 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.61 0.67 7.88e-46 Smoking behavior; LIHC cis rs12701220 0.655 rs7778968 chr7:1144622 C/G cg26769984 chr7:1090371 C7orf50 0.47 5.85 0.3 1.16e-8 Bronchopulmonary dysplasia; LIHC cis rs1113500 0.933 rs11185259 chr1:108635062 A/G cg06207961 chr1:108661230 NA -0.38 -7.33 -0.37 1.7e-12 Growth-regulated protein alpha levels; LIHC cis rs9814567 1.000 rs9856693 chr3:134306913 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.0 -0.54 6.29e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1322512 0.959 rs2623954 chr6:152966001 G/A cg03415253 chr6:152958462 SYNE1 -0.33 -6.22 -0.32 1.47e-9 Tonometry; LIHC trans rs17685 0.753 rs4398845 chr7:75716781 G/A cg19862616 chr7:65841803 NCRNA00174 0.94 19.77 0.73 1.47e-58 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2816062 0.760 rs2745319 chr1:18895078 G/A cg18795169 chr1:18902165 NA -0.8 -18.23 -0.7 2.41e-52 Urate levels in lean individuals; LIHC cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg23262073 chr20:60523788 NA -0.29 -6.12 -0.31 2.51e-9 Body mass index; LIHC cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg07414643 chr4:187882934 NA 0.24 6.15 0.32 2.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9309711 0.666 rs6723126 chr2:3484500 T/C cg15506890 chr2:3487001 NA -0.47 -7.55 -0.38 3.9e-13 Neurofibrillary tangles; LIHC cis rs1023500 0.573 rs133381 chr22:42470608 C/G cg04733989 chr22:42467013 NAGA 0.67 9.57 0.46 2.15e-19 Schizophrenia; LIHC cis rs11098499 0.865 rs11722183 chr4:120280597 A/C cg09307838 chr4:120376055 NA 0.75 11.4 0.52 9.67e-26 Corneal astigmatism; LIHC cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg17971929 chr21:40555470 PSMG1 0.85 10.51 0.49 1.41e-22 Cognitive function; LIHC cis rs9916302 0.904 rs6503507 chr17:37525274 C/T cg07936489 chr17:37558343 FBXL20 0.85 13.71 0.6 2.23e-34 Glomerular filtration rate (creatinine); LIHC cis rs7587476 0.906 rs16852750 chr2:215646683 A/G cg04004882 chr2:215674386 BARD1 0.51 6.23 0.32 1.4e-9 Neuroblastoma; LIHC cis rs36051895 0.632 rs7871515 chr9:5175288 A/G cg02405213 chr9:5042618 JAK2 0.67 11.86 0.54 2.09e-27 Pediatric autoimmune diseases; LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs600806 0.821 rs10127790 chr1:109891133 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.71 -0.38 1.36e-13 Intelligence (multi-trait analysis); LIHC cis rs1336900 0.513 rs56253522 chr1:150614869 C/A cg13175981 chr1:150552382 MCL1 -0.45 -6.19 -0.32 1.76e-9 Blood protein levels; LIHC cis rs7937890 0.561 rs2575849 chr11:14539639 T/A cg02886208 chr11:14281011 SPON1 -0.44 -6.16 -0.32 2.08e-9 Mitochondrial DNA levels; LIHC cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg07414643 chr4:187882934 NA 0.23 5.97 0.31 6.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11252926 0.605 rs10904075 chr10:425667 A/G cg18196295 chr10:418757 DIP2C -0.5 -5.89 -0.3 8.99e-9 Psychosis in Alzheimer's disease; LIHC cis rs1862618 0.671 rs2591961 chr5:56238597 A/G cg24531977 chr5:56204891 C5orf35 0.5 7.21 0.36 3.61e-12 Initial pursuit acceleration; LIHC cis rs11758351 0.866 rs56186759 chr6:26207181 C/T cg03854865 chr6:26224070 HIST1H3E 0.62 7.11 0.36 6.65e-12 Gout;Renal underexcretion gout; LIHC cis rs8180040 0.620 rs11707736 chr3:47069504 G/T cg16586182 chr3:47516702 SCAP 0.47 8.52 0.42 5.13e-16 Colorectal cancer; LIHC cis rs34779708 0.766 rs35308730 chr10:35549796 C/T cg03585969 chr10:35415529 CREM 0.74 10.66 0.5 4.27e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7520050 0.966 rs7540325 chr1:46338217 A/T cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.953 rs114806125 chr8:58182416 C/T cg21724239 chr8:58056113 NA 0.46 6.08 0.31 3.23e-9 Developmental language disorder (linguistic errors); LIHC cis rs6088580 0.561 rs3761147 chr20:32996689 G/T cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs6840360 0.967 rs1105534 chr4:152605312 C/A cg22705602 chr4:152727874 NA -0.31 -6.33 -0.32 7.6e-10 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.684 rs11514164 chr12:38036494 C/T cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.63 -12.45 -0.56 1.38e-29 Prudent dietary pattern; LIHC cis rs7238033 0.663 rs11877630 chr18:43317977 A/G cg20610511 chr18:43302872 SLC14A1 0.39 6.5 0.33 2.89e-10 Bladder cancer; LIHC cis rs7772486 0.875 rs6914813 chr6:146397798 A/G cg23711669 chr6:146136114 FBXO30 0.64 10.66 0.5 4.34e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7089973 0.604 rs7904188 chr10:116610271 G/C cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.17 0.32 1.91e-9 Renal cell carcinoma; LIHC cis rs1969363 0.509 rs8189633 chr12:38065155 C/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Morning vs. evening chronotype; LIHC cis rs1005277 0.579 rs2505197 chr10:38393310 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs227584 0.663 rs2040810 chr17:42243771 C/T cg16434002 chr17:42200994 HDAC5 0.4 5.86 0.3 1.1e-8 Bone mineral density (hip);Bone mineral density; LIHC cis rs6723226 0.750 rs10182170 chr2:32704186 G/A cg02381751 chr2:32503542 YIPF4 0.71 10.74 0.5 2.24e-23 Intelligence (multi-trait analysis); LIHC cis rs4919087 0.590 rs1253397 chr10:99045556 C/T cg25902810 chr10:99078978 FRAT1 -0.61 -6.72 -0.34 7.57e-11 Monocyte count; LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.26e-11 Developmental language disorder (linguistic errors); LIHC cis rs10876993 0.890 rs1689584 chr12:58081478 G/A cg18357645 chr12:58087776 OS9 0.53 8.69 0.43 1.52e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs2067615 0.579 rs7975576 chr12:107132501 A/G cg15890332 chr12:107067104 RFX4 0.27 6.28 0.32 1.02e-9 Heart rate; LIHC cis rs11122272 0.735 rs2790885 chr1:231529925 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs644799 1.000 rs474252 chr11:95619292 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.64 8.79 0.43 7.55e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9457247 0.967 rs402191 chr6:167405553 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC trans rs6489882 0.902 rs4767037 chr12:113372804 A/C cg10175203 chr3:128143634 NA 0.38 6.19 0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg19139277 chr8:28243953 ZNF395 0.7 6.16 0.32 2.06e-9 Musician's dystonia; LIHC cis rs2239547 0.657 rs2071040 chr3:52864860 A/G cg18404041 chr3:52824283 ITIH1 -0.43 -5.83 -0.3 1.3e-8 Schizophrenia; LIHC cis rs2153535 0.580 rs4140586 chr6:8503192 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.37 0.41 1.51e-15 Motion sickness; LIHC cis rs2274273 0.588 rs7155054 chr14:55750662 A/G cg01864836 chr14:55583639 NA -0.34 -5.77 -0.3 1.76e-8 Protein biomarker; LIHC cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg18225595 chr11:63971243 STIP1 0.67 10.13 0.48 2.9e-21 Platelet count; LIHC cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg17747265 chr1:1875780 NA -0.58 -11.35 -0.52 1.45e-25 Body mass index; LIHC cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg12463550 chr7:65579703 CRCP 0.67 7.02 0.36 1.17e-11 Diabetic kidney disease; LIHC cis rs78456975 1.000 rs13431491 chr2:1553808 T/A cg01028140 chr2:1542097 TPO -0.52 -5.97 -0.31 5.83e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs7772486 0.625 rs2050027 chr6:146116113 C/G cg13319975 chr6:146136371 FBXO30 0.36 5.87 0.3 1.02e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs28374715 0.662 rs8038983 chr15:41473316 G/A cg18705301 chr15:41695430 NDUFAF1 -0.85 -9.74 -0.47 5.97e-20 Ulcerative colitis; LIHC cis rs4788570 0.566 rs61171207 chr16:71504798 C/T cg06353428 chr16:71660113 MARVELD3 -1.01 -9.39 -0.45 8.54e-19 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.553 rs4980447 chr11:49591662 T/C cg03929089 chr4:120376271 NA -0.7 -10.26 -0.49 1e-21 Coronary artery disease; LIHC cis rs9372498 0.505 rs1626650 chr6:118654588 C/T cg01339444 chr6:118972232 C6orf204 0.78 6.0 0.31 5.03e-9 Diastolic blood pressure; LIHC cis rs703842 1.000 rs10877012 chr12:58162085 G/T cg18357645 chr12:58087776 OS9 -0.45 -6.91 -0.35 2.45e-11 Multiple sclerosis; LIHC cis rs7927592 0.956 rs948315 chr11:68309140 T/C cg20283391 chr11:68216788 NA -0.51 -7.72 -0.39 1.26e-13 Total body bone mineral density; LIHC trans rs17051917 0.841 rs4943284 chr13:35480729 A/C cg01231434 chr16:23607392 NDUFAB1 -0.93 -6.4 -0.33 5.05e-10 Migraine with aura; LIHC cis rs16958440 1.000 rs62096468 chr18:44637566 C/A cg17192377 chr18:44677553 HDHD2 0.61 6.8 0.35 4.62e-11 Sitting height ratio; LIHC cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg05025164 chr4:1340916 KIAA1530 0.79 12.8 0.57 6.29e-31 Longevity; LIHC cis rs7582720 1.000 rs72936856 chr2:203775712 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs2727020 0.553 rs61904166 chr11:49581461 T/C cg18944383 chr4:111397179 ENPEP 0.25 6.21 0.32 1.51e-9 Coronary artery disease; LIHC cis rs904251 0.772 rs756202 chr6:37460350 C/A cg01843034 chr6:37503916 NA -0.4 -6.53 -0.33 2.31e-10 Cognitive performance; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00620304 chr6:34231334 NA 0.43 6.32 0.32 8.39e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10791097 0.765 rs7943757 chr11:130716157 C/T cg12179176 chr11:130786555 SNX19 0.63 9.83 0.47 3.06e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1789 0.903 rs4470622 chr4:15674175 T/G cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.91 -0.3 8.38e-9 Blood protein levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14782266 chr2:42565367 NA 0.43 6.17 0.32 1.96e-9 Longevity; LIHC trans rs1814175 0.616 rs1794131 chr11:49904194 A/G cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs10489202 0.632 rs202265 chr1:167990231 G/C cg24449463 chr1:168025552 DCAF6 -0.64 -9.67 -0.46 1.03e-19 Schizophrenia; LIHC cis rs7772486 0.790 rs9791313 chr6:146266172 T/C cg23711669 chr6:146136114 FBXO30 -0.62 -10.92 -0.51 4.99e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs4808199 0.947 rs751858 chr19:19602821 G/C cg03709012 chr19:19516395 GATAD2A 1.06 19.2 0.72 2.91e-56 Nonalcoholic fatty liver disease; LIHC cis rs11955398 0.692 rs897672 chr5:59996101 C/G cg02684056 chr5:59996105 DEPDC1B 0.46 6.76 0.34 5.86e-11 Intelligence (multi-trait analysis); LIHC cis rs9388451 0.626 rs3734637 chr6:126081319 G/T cg05901451 chr6:126070800 HEY2 -0.66 -13.63 -0.59 4.44e-34 Brugada syndrome; LIHC cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg09222892 chr1:25734099 RHCE -0.44 -7.92 -0.39 3.48e-14 Plateletcrit;Mean corpuscular volume; LIHC cis rs6066825 0.605 rs4325821 chr20:47224787 T/C cg18078177 chr20:47281410 PREX1 0.49 8.21 0.41 4.53e-15 Colorectal cancer; LIHC cis rs7677751 0.806 rs4864847 chr4:55071953 G/A cg17187183 chr4:55093834 PDGFRA 0.57 7.22 0.36 3.33e-12 Corneal astigmatism; LIHC cis rs7772486 0.754 rs6932863 chr6:146021255 A/T cg05347473 chr6:146136440 FBXO30 -0.38 -6.12 -0.31 2.5e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3806933 0.522 rs12515367 chr5:110447853 A/G cg04022379 chr5:110408740 TSLP 0.57 9.21 0.45 3.36e-18 Eosinophilic esophagitis; LIHC cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg04944784 chr2:26401820 FAM59B -0.72 -9.12 -0.44 6.62e-18 Gut microbiome composition (summer); LIHC cis rs739401 0.611 rs7109088 chr11:3027485 G/T cg25174290 chr11:3078921 CARS 0.58 8.92 0.43 2.79e-17 Longevity; LIHC cis rs9868809 1.000 rs2310997 chr3:48678011 G/C cg07636037 chr3:49044803 WDR6 -0.57 -6.39 -0.33 5.32e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs7572733 0.555 rs6745726 chr2:198934080 A/G cg00792783 chr2:198669748 PLCL1 0.41 5.92 0.31 7.71e-9 Dermatomyositis; LIHC cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.02 -0.44 1.33e-17 Bipolar disorder; LIHC cis rs1062177 1.000 rs2016409 chr5:151126324 G/T cg00977110 chr5:151150581 G3BP1 -0.56 -7.03 -0.36 1.12e-11 Preschool internalizing problems; LIHC cis rs240764 0.658 rs6925823 chr6:101179273 C/A cg09795085 chr6:101329169 ASCC3 -0.44 -6.54 -0.33 2.26e-10 Neuroticism; LIHC cis rs9649213 0.574 rs13238610 chr7:97909277 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.88 -0.3 9.77e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs7534824 0.625 rs2391574 chr1:101373298 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 6.94 0.35 1.96e-11 Refractive astigmatism; LIHC cis rs35306767 0.855 rs12770190 chr10:951262 C/T cg26597838 chr10:835615 NA 1.08 12.47 0.56 1.14e-29 Eosinophil percentage of granulocytes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15985400 chr11:76091674 PRKRIR 0.41 6.2 0.32 1.64e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6904897 0.563 rs6569976 chr6:135224753 A/C cg24558204 chr6:135376177 HBS1L 0.43 6.97 0.35 1.6e-11 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7762018 0.607 rs75010113 chr6:170057441 C/T cg19338460 chr6:170058176 WDR27 -0.9 -9.98 -0.47 9.4e-21 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2290416 0.892 rs62522165 chr8:144675379 C/T cg26536354 chr8:144654954 C8orf73 0.52 5.98 0.31 5.56e-9 Attention deficit hyperactivity disorder; LIHC cis rs8180040 0.729 rs11720439 chr3:47347003 T/G cg16586182 chr3:47516702 SCAP 0.5 8.82 0.43 6.12e-17 Colorectal cancer; LIHC cis rs9549367 0.789 rs2287253 chr13:113891075 G/A cg00898013 chr13:113819073 PROZ 0.41 7.3 0.37 1.98e-12 Platelet distribution width; LIHC cis rs7843479 0.506 rs7818430 chr8:21798429 C/T cg17168535 chr8:21777572 XPO7 0.6 10.94 0.51 4.22e-24 Mean corpuscular volume; LIHC cis rs2976388 1.000 rs2976394 chr8:143763622 C/T cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs7726839 0.540 rs3749615 chr5:601485 C/T cg09021430 chr5:549028 NA -0.43 -8.67 -0.42 1.76e-16 Obesity-related traits; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.04 0.58 8.2e-32 Prudent dietary pattern; LIHC cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.85 -11.08 -0.51 1.35e-24 Alzheimer's disease; LIHC cis rs1728785 0.901 rs698715 chr16:68560896 A/G cg02972257 chr16:68554789 NA -0.56 -6.34 -0.32 7.15e-10 Ulcerative colitis; LIHC cis rs8114671 0.562 rs6087649 chr20:33510662 A/G cg07148914 chr20:33460835 GGT7 0.65 9.86 0.47 2.42e-20 Height; LIHC trans rs983392 0.709 rs7939882 chr11:59973929 A/C cg17275991 chr19:58003312 ZNF419 0.43 6.14 0.32 2.33e-9 Alzheimer's disease (late onset); LIHC cis rs10464366 0.544 rs4723824 chr7:39153698 T/C cg18850127 chr7:39170497 POU6F2 0.46 8.17 0.4 6.03e-15 IgG glycosylation; LIHC cis rs8180040 0.726 rs4682837 chr3:46999707 C/T cg27129171 chr3:47204927 SETD2 0.61 10.66 0.5 4.23e-23 Colorectal cancer; LIHC cis rs763121 0.744 rs5757140 chr22:38957013 T/C cg21395723 chr22:39101663 GTPBP1 0.38 5.94 0.31 7.14e-9 Menopause (age at onset); LIHC cis rs10193935 0.901 rs62142596 chr2:42529339 C/T cg27598129 chr2:42591480 NA -0.68 -10.62 -0.5 5.66e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs2832191 0.967 rs3787660 chr21:30520907 C/T cg08807101 chr21:30365312 RNF160 0.49 7.73 0.39 1.23e-13 Dental caries; LIHC cis rs600806 0.778 rs891380 chr1:110003286 T/G cg16275483 chr1:110013120 SYPL2 -0.52 -6.38 -0.33 5.86e-10 Intelligence (multi-trait analysis); LIHC cis rs2522056 1.000 rs757105 chr5:131795663 C/T cg24060327 chr5:131705240 SLC22A5 0.53 7.16 0.36 4.87e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs1789 0.653 rs13142069 chr4:15593692 C/T cg16509355 chr4:15471240 CC2D2A 0.41 6.58 0.34 1.73e-10 Blood protein levels; LIHC cis rs10744422 1.000 rs4759355 chr12:123316566 A/G cg18912006 chr12:123335444 HIP1R -0.6 -7.2 -0.36 3.76e-12 Schizophrenia; LIHC cis rs9303401 0.614 rs3803752 chr17:56540267 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.1 0.55 2.66e-28 Cognitive test performance; LIHC cis rs9326248 1.000 rs7946257 chr11:117053165 A/G cg11861562 chr11:117069780 TAGLN 0.48 7.98 0.4 2.17e-14 Blood protein levels; LIHC cis rs67981189 0.593 rs2810072 chr14:71387193 A/G cg15816911 chr14:71606274 NA -0.41 -6.49 -0.33 2.99e-10 Schizophrenia; LIHC cis rs1046896 0.514 rs67735447 chr17:80823042 G/T cg02711726 chr17:80685570 FN3KRP -0.45 -8.38 -0.41 1.35e-15 Glycated hemoglobin levels; LIHC cis rs7578199 0.814 rs7570017 chr2:242261434 A/G cg19372975 chr2:242212901 HDLBP -0.59 -5.73 -0.3 2.2e-8 Chronic lymphocytic leukemia; LIHC cis rs7107174 1.000 rs7939646 chr11:78111613 C/T cg02023728 chr11:77925099 USP35 -0.4 -7.62 -0.38 2.59e-13 Testicular germ cell tumor; LIHC cis rs11969893 0.737 rs6930051 chr6:101406108 A/G cg12253828 chr6:101329408 ASCC3 0.95 11.97 0.54 8.26e-28 Economic and political preferences (immigration/crime); LIHC cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg11890956 chr21:40555474 PSMG1 -0.47 -7.68 -0.38 1.64e-13 Cognitive function; LIHC cis rs611744 0.935 rs661036 chr8:109213088 C/T cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs2625529 0.775 rs2723342 chr15:72107699 G/C cg16672083 chr15:72433130 SENP8 -0.33 -6.04 -0.31 4.08e-9 Red blood cell count; LIHC cis rs10789491 1.000 rs1890473 chr1:47149794 C/T cg15501359 chr1:47185051 KIAA0494 0.66 9.42 0.45 6.99e-19 Response to hepatitis C treatment; LIHC cis rs57221529 0.766 rs4957053 chr5:575927 T/C cg09021430 chr5:549028 NA -0.45 -9.08 -0.44 9.1e-18 Lung disease severity in cystic fibrosis; LIHC cis rs1005277 0.579 rs1740737 chr10:38499365 G/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.49e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.73 10.61 0.5 6.17e-23 Lymphocyte counts; LIHC cis rs9905704 0.647 rs2036730 chr17:57038282 A/G cg05425664 chr17:57184151 TRIM37 -0.44 -6.18 -0.32 1.83e-9 Testicular germ cell tumor; LIHC cis rs9534288 0.762 rs9534292 chr13:46611340 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC trans rs9951602 0.512 rs4798994 chr18:76654327 T/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs853679 0.517 rs35227624 chr6:28132726 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs765787 0.530 rs4775822 chr15:45527127 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.05e-13 Uric acid levels; LIHC cis rs12744310 1.000 rs12037588 chr1:41763955 C/G cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.71 0.46 7.76e-20 Electroencephalogram traits; LIHC cis rs7618501 0.521 rs868891 chr3:49949071 A/G cg21467203 chr3:49911342 NA -0.57 -10.52 -0.49 1.27e-22 Intelligence (multi-trait analysis); LIHC cis rs67981189 0.634 rs221896 chr14:71606668 C/G cg15816911 chr14:71606274 NA -0.41 -6.62 -0.34 1.39e-10 Schizophrenia; LIHC cis rs13191362 1.000 rs35103567 chr6:163183400 G/A cg14584255 chr6:163149320 PACRG;PARK2 0.73 5.86 0.3 1.08e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg02290350 chr8:58132656 NA 0.51 9.71 0.46 7.47e-20 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.643 rs3845836 chr2:219504955 C/T cg18887096 chr2:219472410 PLCD4 0.37 6.34 0.32 7.35e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs600806 0.850 rs10776806 chr1:109952127 G/A cg16275483 chr1:110013120 SYPL2 -0.47 -5.77 -0.3 1.78e-8 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.953 rs11253517 chr10:970524 A/G cg26597838 chr10:835615 NA -0.92 -10.66 -0.5 4.12e-23 Eosinophil percentage of granulocytes; LIHC cis rs7089973 0.604 rs7920216 chr10:116611794 G/A cg03647239 chr10:116582469 FAM160B1 0.45 6.56 0.33 2e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs79976124 0.837 rs74327235 chr6:66648353 T/A cg07460842 chr6:66804631 NA 0.65 6.88 0.35 2.89e-11 Type 2 diabetes; LIHC cis rs7264396 1.000 rs224429 chr20:34152018 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.4 -7.05 -0.36 9.94e-12 Total cholesterol levels; LIHC trans rs11039798 0.614 rs11039954 chr11:48741818 A/G cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs763014 0.966 rs15564 chr16:677854 G/T cg00802000 chr16:706648 WDR90 -0.36 -6.07 -0.31 3.32e-9 Height; LIHC cis rs1664789 0.935 rs787545 chr5:53274292 G/A ch.5.1024479R chr5:53302184 ARL15 0.51 7.81 0.39 7.25e-14 Waist circumference adjusted for body mass index; LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs11662586 0.517 rs7230837 chr18:77695384 A/T cg20368463 chr18:77673604 PQLC1 0.61 11.82 0.54 2.92e-27 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg26338869 chr17:61819248 STRADA 0.53 7.11 0.36 6.79e-12 Height; LIHC cis rs9457247 0.765 rs10946203 chr6:167446735 A/C cg23791538 chr6:167370224 RNASET2 -0.53 -8.03 -0.4 1.6e-14 Crohn's disease; LIHC cis rs5769765 1.000 rs1033665 chr22:50252127 A/G cg02269571 chr22:50332266 NA -0.63 -8.94 -0.44 2.44e-17 Schizophrenia; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg07384357 chr20:62499359 TPD52L2 0.38 6.59 0.34 1.64e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs4764124 0.652 rs6488712 chr12:14939332 G/A cg19759883 chr12:14956454 WBP11;C12orf60 0.37 6.7 0.34 8.61e-11 Pubertal anthropometrics; LIHC cis rs870825 0.932 rs28702958 chr4:185575562 C/T cg04058563 chr4:185651563 MLF1IP 0.75 5.88 0.3 9.51e-9 Blood protein levels; LIHC cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC cis rs68170813 0.559 rs74745121 chr7:106958037 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.12e-9 Coronary artery disease; LIHC cis rs7727544 0.660 rs272886 chr5:131665840 T/C cg07395648 chr5:131743802 NA -0.3 -6.26 -0.32 1.12e-9 Blood metabolite levels; LIHC cis rs7647973 0.593 rs28535523 chr3:49848414 C/T cg03060546 chr3:49711283 APEH -0.61 -6.99 -0.35 1.43e-11 Menarche (age at onset); LIHC cis rs7582180 0.614 rs4851309 chr2:100975390 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.43 0.41 9.72e-16 Intelligence (multi-trait analysis); LIHC cis rs2191566 0.639 rs62119176 chr19:44539272 C/T cg20607764 chr19:44506953 ZNF230 -0.38 -6.27 -0.32 1.07e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs3845702 0.736 rs72960664 chr2:180832672 C/T cg01881094 chr2:180872142 CWC22 1.13 9.9 0.47 1.74e-20 Schizophrenia; LIHC cis rs11098499 0.909 rs11098530 chr4:120413154 C/T cg09307838 chr4:120376055 NA 0.77 12.34 0.56 3.42e-29 Corneal astigmatism; LIHC cis rs6089829 0.925 rs2277767 chr20:61666937 G/A cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs9649213 0.593 rs6465675 chr7:97982103 C/T cg08684580 chr7:98029266 BAIAP2L1 0.38 6.0 0.31 5.13e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs1005277 0.579 rs1780136 chr10:38501453 A/G cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs3859192 0.599 rs2270401 chr17:38176256 A/T cg17467752 chr17:38218738 THRA -0.5 -8.57 -0.42 3.74e-16 White blood cell count; LIHC cis rs10791097 0.642 rs7107568 chr11:130779668 T/C cg12179176 chr11:130786555 SNX19 0.92 16.68 0.67 3.87e-46 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs8180040 0.966 rs11130129 chr3:47489885 G/C cg27129171 chr3:47204927 SETD2 -0.56 -9.39 -0.45 8.75e-19 Colorectal cancer; LIHC cis rs1274963 0.601 rs811970 chr3:39196552 A/G cg02254461 chr3:39195904 CSRNP1 -0.52 -6.65 -0.34 1.13e-10 Chronic lymphocytic leukemia; LIHC cis rs9625935 0.518 rs713718 chr22:30314092 A/C cg01021169 chr22:30184971 ASCC2 0.36 6.31 0.32 8.75e-10 Tonsillectomy; LIHC trans rs13381277 1.000 rs9956321 chr18:74328477 C/T cg17352830 chr21:37617589 DOPEY2 -0.55 -6.41 -0.33 4.77e-10 Dental caries; LIHC cis rs7945718 0.621 rs6485989 chr11:12695171 C/T cg25843174 chr11:12811716 TEAD1 0.34 7.74 0.39 1.13e-13 Educational attainment (years of education); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg17403046 chr12:113596797 DDX54;CCDC42B 0.57 6.93 0.35 2.05e-11 Lung function (FEV1); LIHC cis rs9457247 0.765 rs2237276 chr6:167442115 C/T cg12798992 chr6:167411361 FGFR1OP 0.5 7.57 0.38 3.54e-13 Crohn's disease; LIHC cis rs4073582 0.595 rs801734 chr11:65931216 T/C cg16950941 chr11:66035639 RAB1B 0.55 8.25 0.41 3.42e-15 Gout; LIHC cis rs9467773 1.000 rs9467773 chr6:26498426 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.79 0.6 1.01e-34 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.875 rs2224121 chr6:146343214 G/A cg23711669 chr6:146136114 FBXO30 0.6 10.59 0.5 7.58e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs735396 0.770 rs2259820 chr12:121435342 C/T cg02403541 chr12:121454288 C12orf43 0.51 9.05 0.44 1.09e-17 N-glycan levels; LIHC cis rs7772486 0.817 rs9386145 chr6:146363519 A/T cg13319975 chr6:146136371 FBXO30 -0.34 -5.74 -0.3 2.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg04944784 chr2:26401820 FAM59B 0.72 9.29 0.45 1.86e-18 Gut microbiome composition (summer); LIHC cis rs7208859 0.623 rs57486336 chr17:29085731 G/T cg14067834 chr17:29058358 SUZ12P 0.69 6.86 0.35 3.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.18 11.83 0.54 2.74e-27 Platelet count; LIHC cis rs8114671 0.562 rs2424999 chr20:33386430 G/A cg07148914 chr20:33460835 GGT7 0.54 7.77 0.39 9.49e-14 Height; LIHC cis rs10078 0.510 rs2278248 chr5:469570 G/T cg07599136 chr5:415885 AHRR 0.65 10.92 0.51 5.03e-24 Fat distribution (HIV); LIHC cis rs11030122 0.673 rs4910869 chr11:4006438 C/T cg18678763 chr11:4115507 RRM1 -0.58 -8.55 -0.42 4.18e-16 Mean platelet volume;Platelet distribution width; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18030105 chr11:3396237 ZNF195 0.47 6.47 0.33 3.35e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1728785 0.818 rs11075684 chr16:68582365 C/T cg02972257 chr16:68554789 NA -0.54 -6.02 -0.31 4.55e-9 Ulcerative colitis; LIHC cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg11952622 chr19:58962976 ZNF324B 0.48 7.21 0.36 3.66e-12 Uric acid clearance; LIHC cis rs10056811 0.538 rs4632781 chr5:74376658 G/C cg00601450 chr5:74908170 NA 0.55 6.36 0.33 6.46e-10 Coronary artery disease; LIHC cis rs561341 0.883 rs886224 chr17:30229902 T/C cg13647721 chr17:30228624 UTP6 0.8 7.65 0.38 2.07e-13 Hip circumference adjusted for BMI; LIHC cis rs6942756 1.000 rs4440569 chr7:128923907 T/A cg02491457 chr7:128862824 NA -0.64 -9.16 -0.44 5.03e-18 White matter hyperintensity burden; LIHC trans rs75804782 0.641 rs3769125 chr2:239349562 A/G cg01134436 chr17:81009848 B3GNTL1 0.8 6.95 0.35 1.89e-11 Morning vs. evening chronotype;Chronotype; LIHC trans rs7618501 0.633 rs9866695 chr3:50069452 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.58 -9.73 -0.47 6.6e-20 Intelligence (multi-trait analysis); LIHC cis rs72781680 1.000 rs72798411 chr2:24184343 A/G cg08917208 chr2:24149416 ATAD2B 0.95 8.21 0.41 4.55e-15 Lymphocyte counts; LIHC cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg06634786 chr22:41940651 POLR3H -0.79 -9.01 -0.44 1.52e-17 Vitiligo; LIHC cis rs7221595 0.825 rs10521127 chr17:3978268 A/G cg09695851 chr17:3907499 NA 0.56 7.41 0.37 9.66e-13 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; LIHC cis rs711245 0.573 rs11899523 chr2:36800918 T/C cg09467607 chr2:36825704 FEZ2 0.48 7.25 0.36 2.84e-12 Height; LIHC cis rs72949976 0.646 rs1441170 chr2:214033563 A/G cg08319019 chr2:214017104 IKZF2 -0.47 -5.74 -0.3 2.13e-8 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs10489202 0.865 rs744168 chr1:168094079 G/T cg24449463 chr1:168025552 DCAF6 -0.49 -6.18 -0.32 1.78e-9 Schizophrenia; LIHC cis rs875971 0.545 rs12670811 chr7:65823019 C/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.09 0.36 7.56e-12 Aortic root size; LIHC cis rs4268898 0.552 rs4665663 chr2:24372139 G/C cg06627628 chr2:24431161 ITSN2 0.47 6.9 0.35 2.46e-11 Asthma; LIHC trans rs6934970 1.000 rs12204540 chr6:113033306 A/G cg09308777 chr6:169852575 NA 0.6 6.21 0.32 1.5e-9 Bipolar disorder (body mass index interaction); LIHC cis rs12908161 1.000 rs35316992 chr15:85248133 A/G cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs68170813 0.559 rs12536603 chr7:107002573 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.83 -0.3 1.29e-8 Coronary artery disease; LIHC cis rs79149102 0.579 rs7168638 chr15:75280826 T/C cg16226627 chr15:75307476 SCAMP5 0.54 9.71 0.46 7.59e-20 Lung cancer; LIHC cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg06634786 chr22:41940651 POLR3H 0.74 7.67 0.38 1.78e-13 Vitiligo; LIHC cis rs6728642 0.519 rs6721921 chr2:97566501 G/A cg26665480 chr2:98280029 ACTR1B -0.6 -6.44 -0.33 3.96e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs2153535 0.623 rs2327055 chr6:8443145 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.0 0.4 1.99e-14 Motion sickness; LIHC cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.87 8.13 0.4 7.86e-15 Platelet count; LIHC cis rs8017423 0.967 rs12589808 chr14:90719236 C/T cg14092571 chr14:90743983 NA 0.41 6.56 0.33 1.99e-10 Mortality in heart failure; LIHC cis rs1185460 0.967 rs1786690 chr11:118942067 A/G cg23280166 chr11:118938394 VPS11 0.6 8.26 0.41 3.23e-15 Coronary artery disease; LIHC cis rs12908161 1.000 rs12912388 chr15:85344550 T/A cg17507749 chr15:85114479 UBE2QP1 0.63 7.18 0.36 4.38e-12 Schizophrenia; LIHC cis rs4423214 1.000 rs12807718 chr11:71171170 T/C cg05163923 chr11:71159392 DHCR7 0.87 13.22 0.58 1.58e-32 Vitamin D levels; LIHC trans rs3960554 0.808 rs78478514 chr7:75655896 C/T cg19862616 chr7:65841803 NCRNA00174 0.59 8.17 0.4 6.2e-15 Eotaxin levels; LIHC cis rs6502050 0.835 rs35857672 chr17:80078303 G/A cg11859384 chr17:80120422 CCDC57 0.43 5.85 0.3 1.14e-8 Life satisfaction; LIHC cis rs6690583 0.623 rs61769366 chr1:85534062 G/A cg22153463 chr1:85462885 MCOLN2 0.52 5.93 0.31 7.54e-9 Serum sulfate level; LIHC cis rs5769765 0.955 rs4075330 chr22:50303249 G/A cg09182678 chr22:50328711 NA -0.38 -5.79 -0.3 1.63e-8 Schizophrenia; LIHC cis rs7961581 0.748 rs1390201 chr12:71608527 C/T cg05756094 chr12:71608604 NA 0.41 6.67 0.34 1.02e-10 Type 2 diabetes; LIHC cis rs881375 0.933 rs1548784 chr9:123685280 T/C cg14580859 chr9:123691850 NA 0.39 6.83 0.35 3.95e-11 Rheumatoid arthritis; LIHC cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg00149659 chr3:10157352 C3orf10 0.69 7.28 0.37 2.3e-12 Alzheimer's disease; LIHC cis rs765787 0.530 rs1706835 chr15:45517884 G/A cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.75e-10 Uric acid levels; LIHC cis rs2760061 0.598 rs590657 chr1:228117581 A/C cg01200585 chr1:228362443 C1orf69 -0.4 -5.82 -0.3 1.34e-8 Diastolic blood pressure; LIHC cis rs921968 0.541 rs55996799 chr2:219558193 C/G cg02985541 chr2:219472218 PLCD4 -0.39 -5.98 -0.31 5.63e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs477692 0.648 rs10829599 chr10:131321881 C/T cg05714579 chr10:131428358 MGMT 0.41 6.63 0.34 1.3100000000000001e-10 Response to temozolomide; LIHC cis rs600806 0.778 rs10745357 chr1:110001876 G/C cg10127483 chr1:110009974 SYPL2 0.5 6.26 0.32 1.15e-9 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.573 rs7214313 chr17:29138596 T/C cg14067834 chr17:29058358 SUZ12P 0.73 7.42 0.37 9.65e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9611565 0.525 rs1883827 chr22:41703579 A/G cg06634786 chr22:41940651 POLR3H -0.53 -6.14 -0.32 2.23e-9 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17776324 chr12:9903429 NA -0.37 -6.12 -0.31 2.57e-9 Pancreatic cancer; LIHC trans rs1814175 0.817 rs4881645 chr11:49791168 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.85 0.35 3.39e-11 Height; LIHC cis rs11098499 0.955 rs35197422 chr4:120169314 T/G cg09307838 chr4:120376055 NA 0.74 11.0 0.51 2.76e-24 Corneal astigmatism; LIHC cis rs6088590 0.965 rs13040449 chr20:33358901 T/A cg24642439 chr20:33292090 TP53INP2 0.81 11.03 0.51 2.02e-24 Coronary artery disease; LIHC cis rs7927592 0.913 rs66752716 chr11:68273626 C/T cg01657329 chr11:68192670 LRP5 -0.46 -6.02 -0.31 4.6e-9 Total body bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05393045 chr10:119256233 EMX2OS 0.42 6.47 0.33 3.43e-10 Cognitive function; LIHC cis rs1538970 0.924 rs1006216 chr1:45909994 A/G cg05343316 chr1:45956843 TESK2 0.59 8.56 0.42 3.94e-16 Platelet count; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20451727 chr4:83931713 LIN54 -0.56 -6.74 -0.34 6.6e-11 Systolic blood pressure; LIHC cis rs1670533 0.932 rs4690347 chr4:1057328 A/G cg27284194 chr4:1044797 NA 0.59 8.65 0.42 1.97e-16 Recombination rate (females); LIHC cis rs644799 0.562 rs1254989 chr11:95508121 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.69 11.55 0.53 2.71e-26 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs66887589 0.967 rs7678973 chr4:120511817 T/C cg09307838 chr4:120376055 NA -0.5 -7.53 -0.38 4.55e-13 Diastolic blood pressure; LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs11166927 0.934 rs7015426 chr8:140802688 C/G cg16909799 chr8:140841666 TRAPPC9 0.5 7.88 0.39 4.5e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs73001065 0.792 rs16996148 chr19:19658472 G/T cg03709012 chr19:19516395 GATAD2A 0.91 8.23 0.41 3.86e-15 LDL cholesterol; LIHC cis rs1863824 0.502 rs11202058 chr10:88282611 G/A cg07322936 chr10:88137208 NA -0.46 -6.02 -0.31 4.55e-9 Schizophrenia; LIHC cis rs7552404 0.690 rs12723575 chr1:76335203 T/C cg03433033 chr1:76189801 ACADM -0.53 -6.57 -0.33 1.83e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs5769765 1.000 rs764813 chr22:50286172 T/C cg26441486 chr22:50317300 CRELD2 0.35 6.33 0.32 7.65e-10 Schizophrenia; LIHC cis rs1144333 0.510 rs1146652 chr1:76273708 A/G cg22875332 chr1:76189707 ACADM -0.43 -6.54 -0.33 2.18e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs10193935 1.000 rs10193935 chr2:42419829 C/T cg27598129 chr2:42591480 NA -0.73 -11.25 -0.52 3.39e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs2153535 0.580 rs7341383 chr6:8470634 A/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs9522267 0.559 rs9522300 chr13:112236668 C/G cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs769267 0.965 rs4808938 chr19:19401218 G/A cg21559469 chr19:19431446 KIAA0892;SF4 0.41 5.74 0.3 2.09e-8 Tonsillectomy; LIHC trans rs950169 0.579 rs881983 chr15:84647308 C/T cg00571809 chr1:3397113 ARHGEF16 0.38 6.29 0.32 9.5e-10 Schizophrenia; LIHC cis rs2991971 0.967 rs12743512 chr1:45954033 A/G cg24296786 chr1:45957014 TESK2 -0.59 -9.29 -0.45 1.89e-18 High light scatter reticulocyte count; LIHC cis rs6831352 0.918 rs29001202 chr4:100053782 T/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs1559088 0.522 rs7254912 chr19:33554151 A/G cg27124370 chr19:33622961 WDR88 0.56 8.03 0.4 1.55e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg08219700 chr8:58056026 NA 0.52 6.21 0.32 1.56e-9 Developmental language disorder (linguistic errors); LIHC cis rs12824058 0.831 rs11060826 chr12:130809931 G/C cg24229701 chr12:130821962 PIWIL1 0.44 6.78 0.34 5.4e-11 Menopause (age at onset); LIHC cis rs986417 1.000 rs1955699 chr14:61045989 A/G cg27398547 chr14:60952738 C14orf39 0.71 7.81 0.39 7.23e-14 Gut microbiota (bacterial taxa); LIHC cis rs7296418 0.885 rs1790104 chr12:123709409 C/T cg00376283 chr12:123451042 ABCB9 0.69 11.31 0.52 1.99e-25 Platelet count; LIHC cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg25894440 chr7:65020034 NA -0.54 -6.2 -0.32 1.59e-9 Diabetic kidney disease; LIHC cis rs10744422 1.000 rs2292134 chr12:123334033 C/G cg25930673 chr12:123319894 HIP1R -0.93 -12.35 -0.56 3.04e-29 Schizophrenia; LIHC cis rs9527 1.000 rs9527 chr10:104623578 C/T cg15744005 chr10:104629667 AS3MT -0.41 -6.71 -0.34 7.96e-11 Arsenic metabolism; LIHC cis rs2303759 0.676 rs10426452 chr19:49907690 G/A cg24324837 chr19:49891574 CCDC155 0.4 6.32 0.32 8.06e-10 Multiple sclerosis; LIHC cis rs365132 0.517 rs3762974 chr5:176328336 G/A cg16309518 chr5:176445507 NA 0.52 9.85 0.47 2.59e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs17106184 0.892 rs12098132 chr1:51127524 C/A cg07174182 chr1:51127561 FAF1 -0.75 -8.13 -0.4 7.8e-15 Type 2 diabetes; LIHC cis rs7584330 0.554 rs6740722 chr2:238393288 T/C cg08992911 chr2:238395768 MLPH 0.67 6.98 0.35 1.58e-11 Prostate cancer; LIHC trans rs950169 0.545 rs4354897 chr15:84644971 T/C cg24036039 chr1:3397125 ARHGEF16 0.4 6.59 0.34 1.66e-10 Schizophrenia; LIHC cis rs10504229 0.679 rs16921683 chr8:58053270 T/C cg02290350 chr8:58132656 NA 0.31 6.9 0.35 2.57e-11 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs1551570 0.755 rs11667630 chr19:10229297 A/C cg16327482 chr19:10226339 EIF3G -0.5 -8.72 -0.43 1.25e-16 Narcolepsy; LIHC cis rs787274 0.718 rs4979178 chr9:115644335 G/C cg13803584 chr9:115635662 SNX30 -0.51 -6.05 -0.31 3.91e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs4665809 1.000 rs11126340 chr2:26253255 A/G cg27170947 chr2:26402098 FAM59B -0.66 -8.04 -0.4 1.45e-14 Gut microbiome composition (summer); LIHC cis rs2979489 0.740 rs17554408 chr8:30427531 A/G cg26383811 chr8:30366931 RBPMS 0.64 9.34 0.45 1.27e-18 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg18305652 chr10:134549665 INPP5A 0.43 6.29 0.32 9.78e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7089973 0.604 rs11196941 chr10:116596258 A/G cg03647239 chr10:116582469 FAM160B1 0.45 6.6 0.34 1.54e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs970548 0.657 rs11239572 chr10:46088061 C/T cg14222797 chr10:16859974 RSU1 0.49 6.04 0.31 4.04e-9 Total cholesterol levels;Cholesterol, total;HDL cholesterol;HDL cholesterol levels; LIHC cis rs2576037 0.583 rs8094654 chr18:44527397 C/T cg19077165 chr18:44547161 KATNAL2 -0.48 -7.13 -0.36 6.19e-12 Personality dimensions; LIHC cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.44 0.45 6e-19 Bipolar disorder; LIHC cis rs80282103 0.867 rs7099063 chr10:1078547 C/G cg08668510 chr10:1095578 IDI1 0.59 6.09 0.31 3.04e-9 Glomerular filtration rate (creatinine); LIHC cis rs78062588 0.892 rs3811450 chr1:154551032 C/T cg24304309 chr1:154577895 ADAR -0.56 -6.3 -0.32 9.35e-10 Lung cancer; LIHC cis rs1670533 1.000 rs7679432 chr4:1050521 G/A cg27284194 chr4:1044797 NA 0.6 9.02 0.44 1.36e-17 Recombination rate (females); LIHC cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.900 rs73262807 chr10:35496386 C/T cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.5e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4819052 0.808 rs11909411 chr21:46676556 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.58 0.53 2.2e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs13201877 0.591 rs3843990 chr6:137654515 T/C cg16624405 chr10:133607033 NA -0.42 -6.18 -0.32 1.87e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7095944 0.584 rs11245347 chr10:126427037 G/T cg08799069 chr10:126477246 METTL10 -0.37 -6.45 -0.33 3.85e-10 Asthma; LIHC cis rs6665290 0.935 rs6693535 chr1:227197685 G/A cg10327440 chr1:227177885 CDC42BPA -1.19 -25.85 -0.81 2.01e-82 Myeloid white cell count; LIHC cis rs9513627 0.573 rs7325697 chr13:100117793 A/G cg15490075 chr13:100150979 NA 0.52 5.77 0.3 1.79e-8 Obesity-related traits; LIHC cis rs801193 0.967 rs2707841 chr7:66157020 A/G cg00343986 chr7:65444356 GUSB 0.4 5.99 0.31 5.21e-9 Aortic root size; LIHC cis rs7103648 1.000 rs11039225 chr11:47430599 G/A cg20307385 chr11:47447363 PSMC3 1.03 18.02 0.7 1.7e-51 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg04944784 chr2:26401820 FAM59B -0.72 -8.97 -0.44 2.04e-17 Gut microbiome composition (summer); LIHC cis rs600806 0.889 rs585545 chr1:109841662 A/T cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.73 -0.3 2.15e-8 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.931 rs11924597 chr3:48937790 T/C cg06212747 chr3:49208901 KLHDC8B 0.56 7.22 0.36 3.44e-12 Parkinson's disease; LIHC cis rs67311347 0.713 rs9861194 chr3:40309225 C/T cg13409248 chr3:40428643 ENTPD3 0.4 6.37 0.33 6.14e-10 Renal cell carcinoma; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00061764 chr3:67564432 SUCLG2 0.43 6.45 0.33 3.9e-10 Bilirubin levels; LIHC cis rs507080 0.922 rs625513 chr11:118555719 A/C cg04173919 chr11:118528438 PHLDB1 0.35 6.57 0.33 1.9e-10 Serum metabolite levels; LIHC cis rs12791968 0.765 rs2279359 chr11:44999605 A/G cg11846598 chr11:44996168 LOC221122 0.41 6.65 0.34 1.16e-10 Inhibitory control; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21432158 chr12:104530941 NFYB 0.43 6.48 0.33 3.25e-10 Lung function (FEV1/FVC); LIHC cis rs7605378 0.528 rs281787 chr2:200784238 C/T cg23649088 chr2:200775458 C2orf69 -0.57 -8.16 -0.4 6.53e-15 Osteoporosis; LIHC cis rs1555322 0.530 rs2425044 chr20:33869735 C/T cg17927777 chr20:33865990 NA 0.55 6.5 0.33 2.77e-10 Attention deficit hyperactivity disorder; LIHC cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg08219700 chr8:58056026 NA 0.46 5.79 0.3 1.63e-8 Developmental language disorder (linguistic errors); LIHC cis rs6964587 0.655 rs6965864 chr7:91595596 A/G cg17063962 chr7:91808500 NA 0.63 11.3 0.52 2.29e-25 Breast cancer; LIHC cis rs9549367 0.789 rs12869947 chr13:113896156 A/G cg00898013 chr13:113819073 PROZ -0.43 -7.44 -0.37 8.39e-13 Platelet distribution width; LIHC cis rs208520 0.690 rs207091 chr6:66799847 G/T cg07460842 chr6:66804631 NA -0.84 -9.29 -0.45 1.86e-18 Exhaled nitric oxide output; LIHC cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg12016809 chr21:47604291 C21orf56 0.43 6.37 0.33 6.08e-10 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg00091569 chr3:40428383 ENTPD3 -0.38 -6.53 -0.33 2.36e-10 Renal cell carcinoma; LIHC cis rs7799006 0.723 rs2270052 chr7:2291399 C/T cg02951883 chr7:2050386 MAD1L1 -0.4 -6.17 -0.32 1.95e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg05185784 chr16:90016020 DEF8 -0.48 -6.18 -0.32 1.84e-9 Skin colour saturation; LIHC cis rs8067545 0.516 rs11869258 chr17:20206898 G/A cg13482628 chr17:19912719 NA -0.41 -6.73 -0.34 7.17e-11 Schizophrenia; LIHC cis rs6450176 0.564 rs31227 chr5:53326467 G/C ch.5.1024479R chr5:53302184 ARL15 -0.75 -13.51 -0.59 1.27e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14509581 chr15:68522181 CLN6 0.45 6.09 0.31 3e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg21448741 chr8:58168803 NA 0.35 6.55 0.33 2.1e-10 Developmental language disorder (linguistic errors); LIHC cis rs4906332 1.000 rs28711288 chr14:103906126 T/C cg19000871 chr14:103996768 TRMT61A -0.42 -7.17 -0.36 4.8e-12 Coronary artery disease; LIHC cis rs10878977 0.565 rs11177657 chr12:69809909 T/C cg17330252 chr12:69809627 NA 0.37 5.83 0.3 1.3e-8 Colorectal cancer; LIHC cis rs11195062 0.766 rs1935465 chr10:112029300 G/A cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.75 -0.3 2.01e-8 Multiple myeloma; LIHC cis rs921968 0.542 rs588182 chr2:219412335 C/A cg02176678 chr2:219576539 TTLL4 0.53 7.41 0.37 1.03e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs6121246 0.542 rs2376990 chr20:30238744 G/A cg13852791 chr20:30311386 BCL2L1 0.85 8.31 0.41 2.31e-15 Mean corpuscular hemoglobin; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg14504603 chr2:211341483 LANCL1;CPS1 0.36 6.23 0.32 1.36e-9 Calcium levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19502932 chr11:6640663 TPP1 0.42 6.03 0.31 4.14e-9 Lung function (FEV1/FVC); LIHC cis rs2594714 0.515 rs10411270 chr19:13940838 A/T cg18576835 chr19:13944261 NA -0.33 -6.59 -0.34 1.66e-10 Breast cancer; LIHC cis rs2153535 0.580 rs2327064 chr6:8454052 C/T cg23788917 chr6:8435910 SLC35B3 0.62 8.75 0.43 9.55e-17 Motion sickness; LIHC cis rs7587476 0.682 rs13009646 chr2:215691259 T/A cg04004882 chr2:215674386 BARD1 0.57 7.8 0.39 7.33e-14 Neuroblastoma; LIHC cis rs12477438 0.520 rs4402818 chr2:99717608 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.2 20.79 0.75 1.21e-62 Chronic sinus infection; LIHC cis rs4803468 1.000 rs284656 chr19:41929251 T/C cg14132834 chr19:41945861 ATP5SL -0.46 -6.79 -0.34 4.91e-11 Height; LIHC trans rs79389047 0.850 rs10000631 chr4:157662289 C/T cg18148021 chr14:56616059 PELI2 0.41 6.26 0.32 1.15e-9 Plateletcrit; LIHC trans rs1814175 0.645 rs10839382 chr11:49823172 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.05 -0.74 1.13e-59 Height; LIHC cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.51 0.33 2.68e-10 Bipolar disorder; LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg02869306 chr7:64672164 INTS4L1 0.28 6.16 0.32 2e-9 Calcium levels; LIHC cis rs1448094 0.512 rs4540904 chr12:86235472 A/G cg02569458 chr12:86230093 RASSF9 0.48 6.3 0.32 9.01e-10 Major depressive disorder; LIHC cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg19045956 chr2:200819837 C2orf60;C2orf47 0.33 5.79 0.3 1.57e-8 Osteoporosis; LIHC cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.11e-8 Bipolar disorder; LIHC cis rs3818285 0.504 rs7100154 chr10:111650150 T/C cg00817464 chr10:111662876 XPNPEP1 -0.46 -7.25 -0.37 2.74e-12 Superior crus of antihelix expression; LIHC cis rs56235845 0.694 rs6876677 chr5:176755342 T/C cg16006841 chr5:176797999 RGS14 0.57 7.63 0.38 2.42e-13 Hemoglobin concentration;Hematocrit; LIHC trans rs208520 1.000 rs12190773 chr6:66968194 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.63 6.69 0.34 9.29e-11 Exhaled nitric oxide output; LIHC cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs8180040 0.871 rs11716661 chr3:47517773 G/T cg16586182 chr3:47516702 SCAP 0.6 11.76 0.54 4.7e-27 Colorectal cancer; LIHC cis rs10752881 1.000 rs12028732 chr1:182985525 G/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs17152411 1.000 rs17152433 chr10:126670356 G/A cg07906193 chr10:126599966 NA 0.36 6.04 0.31 4.01e-9 Height; LIHC cis rs13191362 0.872 rs13213421 chr6:163203805 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.81 6.81 0.35 4.33e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2901460 0.527 rs10167456 chr2:62112839 G/A cg02183531 chr2:62113199 CCT4 -0.41 -6.04 -0.31 4e-9 Mean corpuscular volume; LIHC cis rs2933343 0.700 rs1680778 chr3:128614185 A/C cg25356066 chr3:128598488 ACAD9 0.56 7.74 0.39 1.1e-13 IgG glycosylation; LIHC cis rs4332037 0.510 rs58673065 chr7:1885600 A/G cg23422044 chr7:1970798 MAD1L1 -0.54 -8.95 -0.44 2.24e-17 Bipolar disorder; LIHC trans rs1005277 0.540 rs7903942 chr10:37929276 C/T cg23533926 chr12:111358616 MYL2 0.33 6.4 0.33 4.98e-10 Extrinsic epigenetic age acceleration; LIHC trans rs916888 0.773 rs199447 chr17:44812188 C/T cg13957321 chr17:43675089 NA 0.49 7.72 0.39 1.34e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs600806 0.778 rs6693932 chr1:110003575 T/C cg16275483 chr1:110013120 SYPL2 -0.52 -6.3 -0.32 9.12e-10 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.591 rs4585083 chr2:136486342 C/T cg07169764 chr2:136633963 MCM6 0.75 9.4 0.45 8.12e-19 Corneal structure; LIHC cis rs898097 0.625 rs7406464 chr17:80891460 A/G cg15664640 chr17:80829946 TBCD -0.42 -7.02 -0.35 1.22e-11 Breast cancer; LIHC cis rs11190604 1.000 rs9420785 chr10:102240451 C/G cg07080220 chr10:102295463 HIF1AN 0.51 7.24 0.36 2.99e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs12824058 0.831 rs12322456 chr12:130813594 A/G cg24229701 chr12:130821962 PIWIL1 0.46 6.97 0.35 1.63e-11 Menopause (age at onset); LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg13012494 chr21:47604986 C21orf56 -0.37 -5.91 -0.3 8.21e-9 Testicular germ cell tumor; LIHC cis rs72781680 0.756 rs2551337 chr2:24006886 C/T cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.2e-9 Lymphocyte counts; LIHC cis rs4654899 1.000 rs7550267 chr1:21448792 T/C cg08539965 chr1:21396338 EIF4G3 0.33 5.85 0.3 1.12e-8 Superior frontal gyrus grey matter volume; LIHC cis rs2354432 0.607 rs3820130 chr1:146724003 A/G cg25205988 chr1:146714368 CHD1L -0.91 -11.69 -0.53 8.72e-27 Mitochondrial DNA levels; LIHC cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg23758822 chr17:41437982 NA 0.92 16.92 0.67 4.48e-47 Menopause (age at onset); LIHC cis rs2777491 1.000 rs316613 chr15:41747598 G/A cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.24 -0.45 2.77e-18 Ulcerative colitis; LIHC cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.13 0.44 6.09e-18 Bipolar disorder; LIHC cis rs7216064 1.000 rs34872586 chr17:65863466 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs4906332 1.000 rs34479426 chr14:103881823 G/C cg19000871 chr14:103996768 TRMT61A -0.45 -7.71 -0.38 1.41e-13 Coronary artery disease; LIHC cis rs4665809 0.878 rs35709953 chr2:26334997 G/A cg04944784 chr2:26401820 FAM59B 0.59 6.47 0.33 3.34e-10 Gut microbiome composition (summer); LIHC trans rs12620999 0.941 rs4408676 chr2:238085280 C/T cg15676719 chr1:167598521 RCSD1 -0.38 -7.17 -0.36 4.59e-12 Systemic lupus erythematosus; LIHC cis rs2839186 0.681 rs13047198 chr21:47701835 T/C cg09417038 chr21:47716443 C21orf57 -0.58 -8.58 -0.42 3.47e-16 Testicular germ cell tumor; LIHC cis rs7584330 0.554 rs111512641 chr2:238429538 G/A cg08992911 chr2:238395768 MLPH 0.55 6.44 0.33 4.12e-10 Prostate cancer; LIHC cis rs2153535 0.580 rs9328484 chr6:8524843 A/T cg23788917 chr6:8435910 SLC35B3 0.63 8.93 0.43 2.68e-17 Motion sickness; LIHC cis rs72627123 0.867 rs73303116 chr14:74483615 C/T cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.75 0.3 1.97e-8 Morning vs. evening chronotype; LIHC cis rs4474465 0.688 rs7929656 chr11:78276416 T/C cg27205649 chr11:78285834 NARS2 0.49 7.67 0.38 1.76e-13 Alzheimer's disease (survival time); LIHC cis rs10927875 0.632 rs2013745 chr1:16126676 G/A cg07117364 chr1:16154769 NA -0.42 -7.34 -0.37 1.62e-12 Dilated cardiomyopathy; LIHC cis rs2933343 0.761 rs789225 chr3:128600229 G/A cg25356066 chr3:128598488 ACAD9 0.55 7.66 0.38 1.9e-13 IgG glycosylation; LIHC cis rs10927875 0.619 rs12121764 chr1:16138059 A/T cg21385522 chr1:16154831 NA -0.75 -10.74 -0.5 2.21e-23 Dilated cardiomyopathy; LIHC cis rs17253792 0.822 rs76164147 chr14:56140369 T/C cg01858014 chr14:56050164 KTN1 -0.7 -7.28 -0.37 2.32e-12 Putamen volume; LIHC trans rs2288327 0.591 rs2562845 chr2:179514433 T/C cg14011486 chr1:26737247 LIN28 0.43 6.2 0.32 1.59e-9 Atrial fibrillation; LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg03354898 chr7:1950403 MAD1L1 -0.37 -5.72 -0.3 2.3e-8 Bipolar disorder and schizophrenia; LIHC cis rs9911578 0.835 rs2301867 chr17:56480074 T/A cg05425664 chr17:57184151 TRIM37 0.57 8.19 0.4 5.28e-15 Intelligence (multi-trait analysis); LIHC cis rs9325144 0.647 rs35138700 chr12:38804474 C/T cg26384229 chr12:38710491 ALG10B -0.55 -7.53 -0.38 4.67e-13 Morning vs. evening chronotype; LIHC cis rs7829975 0.514 rs2976929 chr8:8258712 T/C cg06636001 chr8:8085503 FLJ10661 0.53 8.88 0.43 3.97e-17 Mood instability; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07077080 chr8:30585289 GSR 0.42 6.92 0.35 2.18e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4808199 0.948 rs8108647 chr19:19427623 A/G cg03709012 chr19:19516395 GATAD2A 0.99 16.23 0.66 2.46e-44 Nonalcoholic fatty liver disease; LIHC cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg07308232 chr7:1071921 C7orf50 -0.44 -7.03 -0.36 1.14e-11 Longevity;Endometriosis; LIHC trans rs9687065 1.000 rs10078963 chr5:148400424 G/A cg00646241 chr11:70563878 SHANK2 0.36 6.04 0.31 3.94e-9 Diastolic blood pressure; LIHC cis rs1707322 0.963 rs10789478 chr1:46350506 C/T cg03146154 chr1:46216737 IPP 0.48 7.56 0.38 3.83e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3736485 0.966 rs4775944 chr15:51775610 T/C cg08986416 chr15:51914746 DMXL2 -0.41 -6.15 -0.32 2.11e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs9858542 1.000 rs9882740 chr3:49702484 T/C cg21659725 chr3:3221576 CRBN -0.54 -6.05 -0.31 3.74e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2479724 0.811 rs8393 chr6:41757836 C/A cg17623882 chr6:41773611 USP49 0.55 8.77 0.43 8.44e-17 Menarche (age at onset); LIHC cis rs7131987 0.903 rs7970390 chr12:29398655 A/G cg21522988 chr12:29376872 FAR2 0.3 6.99 0.35 1.44e-11 QT interval; LIHC cis rs2380220 0.935 rs7744491 chr6:95994980 T/G cg15832292 chr6:96025679 MANEA 0.62 7.17 0.36 4.71e-12 Behavioural disinhibition (generation interaction); LIHC cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.78 -0.54 3.97e-27 Alzheimer's disease; LIHC cis rs11190604 1.000 rs10883505 chr10:102280772 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.08 0.4 1.15e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6426558 0.515 rs7412928 chr1:227332148 C/T cg10327440 chr1:227177885 CDC42BPA -0.44 -6.62 -0.34 1.41e-10 Neutrophil percentage of white cells; LIHC cis rs9911578 1.000 rs1631237 chr17:56734695 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC trans rs1459104 0.759 rs7939392 chr11:55257285 C/T cg15704280 chr7:45808275 SEPT13 0.69 7.22 0.36 3.41e-12 Body mass index; LIHC cis rs12701220 0.689 rs6973645 chr7:1112246 C/T cg02733842 chr7:1102375 C7orf50 -0.69 -7.66 -0.38 1.97e-13 Bronchopulmonary dysplasia; LIHC trans rs10411161 0.702 rs2867319 chr19:52397160 T/C cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs1538970 0.962 rs9429160 chr1:45827968 G/T cg05343316 chr1:45956843 TESK2 0.6 9.01 0.44 1.51e-17 Platelet count; LIHC cis rs7412746 0.658 rs6660845 chr1:150841066 G/A cg18016565 chr1:150552671 MCL1 0.56 10.27 0.49 9.3e-22 Melanoma; LIHC cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg14004847 chr7:1930337 MAD1L1 -0.41 -5.78 -0.3 1.69e-8 Bipolar disorder and schizophrenia; LIHC cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg10411590 chr13:21900810 NA 0.42 6.83 0.35 3.88e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs965469 0.779 rs6133039 chr20:3385006 C/T cg25506879 chr20:3388711 C20orf194 -0.52 -6.36 -0.33 6.5e-10 IFN-related cytopenia; LIHC cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.59 9.26 0.45 2.24e-18 Schizophrenia; LIHC cis rs763121 0.819 rs4560233 chr22:38982442 A/T cg14440974 chr22:39074834 NA -0.44 -7.1 -0.36 7.19e-12 Menopause (age at onset); LIHC cis rs7937682 0.681 rs7107378 chr11:111401840 C/A cg09085632 chr11:111637200 PPP2R1B 0.46 6.04 0.31 4e-9 Primary sclerosing cholangitis; LIHC cis rs2749592 1.000 rs2749592 chr10:38258842 A/C cg00409905 chr10:38381863 ZNF37A -0.47 -7.42 -0.37 9.06e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs67460515 0.926 rs13062740 chr3:161024208 G/A cg03342759 chr3:160939853 NMD3 -0.64 -9.68 -0.46 9.39e-20 Parkinson's disease; LIHC cis rs9296092 0.517 rs76662639 chr6:33508476 G/A cg13560919 chr6:33536144 NA -0.38 -6.06 -0.31 3.53e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs139156536 1 rs139156536 chr17:38164432 TTTTA/T cg17344932 chr17:38183730 MED24;SNORD124 -0.65 -11.98 -0.54 7.41e-28 Lymphocyte percentage of white cells; LIHC cis rs3106136 0.678 rs6532484 chr4:95297118 C/T cg11021082 chr4:95130006 SMARCAD1 0.36 6.14 0.32 2.27e-9 Capecitabine sensitivity; LIHC cis rs4409675 0.576 rs3766396 chr1:28221554 C/T cg23691781 chr1:28212827 C1orf38 -0.36 -8.43 -0.41 9.85e-16 Corneal astigmatism; LIHC cis rs5769765 0.862 rs56377703 chr22:50306940 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.88 -10.88 -0.51 7.1e-24 Schizophrenia; LIHC cis rs17376456 0.877 rs10066791 chr5:93350255 G/T cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.53e-21 Diabetic retinopathy; LIHC cis rs6952808 0.771 rs10244946 chr7:1921068 A/G cg02951883 chr7:2050386 MAD1L1 0.57 8.7 0.43 1.42e-16 Bipolar disorder and schizophrenia; LIHC cis rs17102423 0.964 rs8015330 chr14:65602183 C/T cg11161011 chr14:65562177 MAX -0.44 -6.0 -0.31 5.08e-9 Obesity-related traits; LIHC cis rs4845570 1.000 rs4845356 chr1:151759223 T/A cg07092448 chr1:151763213 TDRKH 0.7 7.88 0.39 4.55e-14 Coronary artery disease; LIHC cis rs3770081 0.590 rs79329534 chr2:86458631 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.74 -7.23 -0.36 3.13e-12 Facial emotion recognition (sad faces); LIHC trans rs11039798 0.764 rs11040030 chr11:48800985 C/T cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs6582630 0.502 rs10880388 chr12:38401341 A/T cg26384229 chr12:38710491 ALG10B 0.6 8.29 0.41 2.71e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg11062466 chr8:58055876 NA 0.51 7.61 0.38 2.72e-13 Developmental language disorder (linguistic errors); LIHC cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg16926213 chr1:1841314 NA 0.32 5.93 0.31 7.41e-9 Body mass index; LIHC cis rs6964587 1.000 rs6465347 chr7:91693837 A/G cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs2268241 0.938 rs17879003 chr21:34778527 C/T cg14850771 chr21:34775459 IFNGR2 0.91 13.85 0.6 6.07e-35 Obesity-related traits; LIHC trans rs877282 0.898 rs11253347 chr10:765769 A/G cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs3849570 0.961 rs10154945 chr3:81833766 A/C cg07356753 chr3:81810745 GBE1 -0.63 -10.57 -0.5 8.56e-23 Waist circumference;Body mass index; LIHC cis rs9583531 0.600 rs4773240 chr13:111360585 G/A cg15841412 chr13:111365552 ING1 0.47 5.87 0.3 1.04e-8 Coronary artery disease; LIHC cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.15 -0.32 2.19e-9 Aortic root size; LIHC cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg02187348 chr16:89574699 SPG7 0.62 9.91 0.47 1.64e-20 Multiple myeloma (IgH translocation); LIHC cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg14004847 chr7:1930337 MAD1L1 -0.42 -6.11 -0.31 2.72e-9 Bipolar disorder and schizophrenia; LIHC cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.08 11.64 0.53 1.34e-26 Platelet count; LIHC cis rs8062405 0.755 rs4149398 chr16:28608938 C/G cg07451762 chr16:28383216 NA 0.39 6.87 0.35 3.05e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9296092 0.560 rs62407561 chr6:33528103 T/C cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19553056 chr4:142142166 ZNF330 0.46 6.59 0.34 1.68e-10 Pancreatic cancer; LIHC cis rs7267979 1.000 rs6083805 chr20:25317356 T/C cg24626310 chr20:25276739 ABHD12;PYGB -0.47 -6.8 -0.35 4.74e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2834188 0.961 rs8130807 chr21:34690013 A/G cg04842828 chr21:34696676 IFNAR1 0.45 6.14 0.32 2.31e-9 Narcolepsy; LIHC cis rs8072100 0.782 rs28507314 chr17:45551402 C/T cg08085267 chr17:45401833 C17orf57 -0.44 -6.5 -0.33 2.82e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs11098499 1.000 rs13116504 chr4:120209412 A/C cg25214090 chr10:38739885 LOC399744 0.51 7.9 0.39 3.83e-14 Corneal astigmatism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27305525 chr1:154955752 FLAD1 0.38 6.37 0.33 5.96e-10 Cognitive function; LIHC cis rs35306767 0.715 rs12772979 chr10:1034412 C/T cg26597838 chr10:835615 NA 0.91 8.21 0.41 4.74e-15 Eosinophil percentage of granulocytes; LIHC cis rs7312774 0.618 rs73385161 chr12:107300164 G/A cg16260113 chr12:107380972 MTERFD3 0.75 9.73 0.47 6.53e-20 Severe influenza A (H1N1) infection; LIHC cis rs769267 0.930 rs10402451 chr19:19608537 A/G cg03709012 chr19:19516395 GATAD2A 1.01 18.36 0.7 6.84e-53 Tonsillectomy; LIHC cis rs2075371 1.000 rs2598288 chr7:133977304 A/T cg20476274 chr7:133979776 SLC35B4 0.76 13.09 0.58 5.08e-32 Mean platelet volume; LIHC cis rs3806843 0.801 rs2531358 chr5:140117437 A/G cg19875535 chr5:140030758 IK -0.39 -6.35 -0.32 6.69e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs9640161 0.783 rs35435439 chr7:150063534 C/T cg10018233 chr7:150070692 REPIN1 0.7 12.46 0.56 1.2e-29 Blood protein levels;Circulating chemerin levels; LIHC cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.84 8.11 0.4 9.44e-15 Platelet count; LIHC cis rs1185460 0.967 rs1307145 chr11:118950217 C/G cg23280166 chr11:118938394 VPS11 0.59 7.89 0.39 4.14e-14 Coronary artery disease; LIHC cis rs988712 0.516 rs6484320 chr11:27703188 T/A cg18117895 chr11:27722066 BDNF -0.51 -7.13 -0.36 6.04e-12 Obesity; LIHC cis rs28830936 1.000 rs17677991 chr15:42032383 C/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -5.8 -0.3 1.48e-8 Diastolic blood pressure; LIHC cis rs10744422 1.000 rs2292135 chr12:123334075 G/A cg18912006 chr12:123335444 HIP1R -0.63 -7.58 -0.38 3.18e-13 Schizophrenia; LIHC cis rs2795502 0.873 rs3121327 chr10:43388285 G/A cg20628663 chr10:43360327 NA 0.46 6.89 0.35 2.65e-11 Blood protein levels; LIHC cis rs7165170 0.678 rs10083558 chr15:91202504 C/A cg26821196 chr15:91095069 CRTC3 -0.36 -6.52 -0.33 2.49e-10 Crohn's disease;Inflammatory bowel disease; LIHC cis rs6088590 1.000 rs6119530 chr20:33403930 A/G cg06115741 chr20:33292138 TP53INP2 0.57 7.89 0.39 4.18e-14 Coronary artery disease; LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg26338869 chr17:61819248 STRADA 0.54 7.42 0.37 9.33e-13 Height; LIHC cis rs600806 0.778 rs2787015 chr1:110009434 A/C cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.41 -0.37 1.03e-12 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.600 rs1128419 chr11:1010750 G/A cg06064525 chr11:970664 AP2A2 -0.45 -10.74 -0.5 2.15e-23 Alzheimer's disease (late onset); LIHC trans rs9834975 0.565 rs4677957 chr3:122257767 G/A cg18228109 chr6:162684441 PARK2 0.33 6.09 0.31 3.04e-9 Diastolic blood pressure; LIHC cis rs2075371 0.933 rs2544182 chr7:133949793 C/T cg20476274 chr7:133979776 SLC35B4 0.7 11.67 0.53 1.02e-26 Mean platelet volume; LIHC cis rs17345786 0.906 rs55710435 chr3:101180330 G/A cg12386194 chr3:101231763 SENP7 0.6 7.87 0.39 4.57e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs425277 1.000 rs262647 chr1:2095699 C/T cg24578937 chr1:2090814 PRKCZ 0.5 9.15 0.44 5.35e-18 Height; LIHC cis rs748404 0.560 rs572837 chr15:43823813 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.4 6.02 0.31 4.54e-9 Lung cancer; LIHC cis rs11166927 1.000 rs13256946 chr8:140805101 G/A cg16909799 chr8:140841666 TRAPPC9 0.51 8.05 0.4 1.38e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs1371867 0.846 rs1788181 chr8:101334068 C/T cg06636551 chr8:101224915 SPAG1 -0.47 -8.72 -0.43 1.26e-16 Atrioventricular conduction; LIHC cis rs4629710 0.592 rs4310080 chr6:131538377 T/G cg12606694 chr6:131520996 AKAP7 0.61 7.15 0.36 5.42e-12 Multiple myeloma (IgH translocation); LIHC cis rs2963155 0.518 rs72801029 chr5:142625806 T/C cg17617527 chr5:142782415 NR3C1 0.93 8.18 0.4 5.53e-15 Breast cancer; LIHC cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg10802521 chr3:52805072 NEK4 0.43 7.0 0.35 1.34e-11 Bipolar disorder; LIHC cis rs11098699 0.898 rs2047202 chr4:124233100 C/G cg09941581 chr4:124220074 SPATA5 -0.3 -5.72 -0.3 2.3e-8 Mosquito bite size; LIHC cis rs2574704 0.851 rs3856795 chr3:11630484 G/A cg15876825 chr3:11651881 VGLL4 -0.48 -7.78 -0.39 8.62e-14 Body mass index; LIHC cis rs8180040 0.805 rs17410853 chr3:47363971 G/T cg27129171 chr3:47204927 SETD2 -0.53 -8.42 -0.41 1.01e-15 Colorectal cancer; LIHC cis rs67981189 0.552 rs9323556 chr14:71469512 T/C cg15816911 chr14:71606274 NA 0.41 6.54 0.33 2.2e-10 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00011284 chr16:53469344 RBL2 0.5 7.71 0.38 1.43e-13 Cognitive function; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg02869306 chr7:64672164 INTS4L1 -0.3 -6.41 -0.33 4.69e-10 Calcium levels; LIHC cis rs6121246 0.909 rs6058463 chr20:30385192 C/T cg13852791 chr20:30311386 BCL2L1 0.92 9.63 0.46 1.39e-19 Mean corpuscular hemoglobin; LIHC cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg00149659 chr3:10157352 C3orf10 0.64 6.95 0.35 1.88e-11 Alzheimer's disease; LIHC cis rs2180341 0.814 rs7768435 chr6:127737038 A/C cg27446573 chr6:127587934 RNF146 0.79 13.09 0.58 5.05e-32 Breast cancer; LIHC cis rs2439831 1.000 rs2444250 chr15:43785051 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.68 0.59 2.85e-34 Lung cancer in ever smokers; LIHC cis rs9811920 0.638 rs793474 chr3:99544380 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.51 -7.2 -0.36 3.88e-12 Axial length; LIHC cis rs1707322 1.000 rs785504 chr1:46595696 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.6 -0.34 1.57e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17384381 1.000 rs12758768 chr1:85835206 C/T cg16011679 chr1:85725395 C1orf52 0.81 8.24 0.41 3.73e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7208859 0.573 rs79505916 chr17:29062326 C/T cg13385521 chr17:29058706 SUZ12P 0.84 8.31 0.41 2.33e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs903552 0.736 rs9806495 chr15:102008059 G/A cg06707286 chr15:102010195 PCSK6 -0.53 -7.57 -0.38 3.43e-13 Diabetic kidney disease; LIHC cis rs244293 0.673 rs12944690 chr17:53029614 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.43 -5.96 -0.31 6.18e-9 Menarche (age at onset); LIHC cis rs881375 0.702 rs3761847 chr9:123690239 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.42 6.1 0.31 2.86e-9 Rheumatoid arthritis; LIHC cis rs1943345 0.642 rs642669 chr11:82892454 A/T cg07047830 chr11:82868014 PCF11 0.54 9.26 0.45 2.31e-18 Obesity-related traits; LIHC cis rs263063 0.834 rs710957 chr19:5054345 G/C cg18473234 chr19:5097819 KDM4B 0.56 6.98 0.35 1.5e-11 Periodontitis (CDC/AAP); LIHC cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg01017244 chr2:74357527 NA -0.61 -10.93 -0.51 4.92e-24 Gestational age at birth (maternal effect); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14875093 chr19:38398164 WDR87;SIPA1L3 0.38 6.57 0.33 1.89e-10 Cognitive function; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.82 0.39 6.59e-14 Height; LIHC trans rs1814175 0.746 rs10839429 chr11:49906845 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs2991971 0.967 rs6661321 chr1:45954599 C/G cg24296786 chr1:45957014 TESK2 0.59 9.25 0.45 2.45e-18 High light scatter reticulocyte count; LIHC cis rs3741798 1.000 rs17303178 chr12:12485351 G/A cg08615371 chr12:12503544 MANSC1 0.99 7.88 0.39 4.4e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs1046896 0.594 rs67813226 chr17:80851134 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.16 0.32 2.08e-9 Glycated hemoglobin levels; LIHC cis rs2439831 0.681 rs7175434 chr15:43628542 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.55 0.53 2.81e-26 Lung cancer in ever smokers; LIHC cis rs2439831 0.557 rs13329084 chr15:44151063 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.53 -6.54 -0.33 2.3e-10 Lung cancer in ever smokers; LIHC cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.25 -0.61 1.78e-36 Alzheimer's disease; LIHC cis rs9902453 0.791 rs6505141 chr17:27998187 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.22 0.58 1.62e-32 Coffee consumption (cups per day); LIHC cis rs6089829 0.962 rs4586690 chr20:61658595 G/T cg03213289 chr20:61660250 NA 0.51 9.06 0.44 1.04e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs7937890 0.587 rs11023204 chr11:14411223 C/A cg02886208 chr11:14281011 SPON1 -0.51 -7.22 -0.36 3.34e-12 Mitochondrial DNA levels; LIHC cis rs250677 0.652 rs36045 chr5:148441184 A/G cg12140854 chr5:148520817 ABLIM3 0.52 5.97 0.31 6.08e-9 Breast cancer; LIHC cis rs8180040 0.620 rs6767907 chr3:47162661 C/T cg27129171 chr3:47204927 SETD2 -0.57 -9.45 -0.45 5.63e-19 Colorectal cancer; LIHC cis rs13161895 0.818 rs114211674 chr5:179484518 A/C cg02702477 chr5:179499311 RNF130 0.9 11.93 0.54 1.11e-27 LDL cholesterol; LIHC cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg00149659 chr3:10157352 C3orf10 0.6 6.58 0.33 1.82e-10 Alzheimer's disease; LIHC cis rs875971 0.825 rs1860472 chr7:66082723 T/C cg18876405 chr7:65276391 NA -0.34 -6.24 -0.32 1.3e-9 Aortic root size; LIHC cis rs9583531 0.600 rs9555726 chr13:111368316 C/T cg24331049 chr13:111365604 ING1 0.63 10.59 0.5 7.25e-23 Coronary artery disease; LIHC cis rs6867032 0.917 rs10474733 chr5:2004160 A/G cg26168224 chr5:2018326 NA -0.28 -6.99 -0.35 1.45e-11 Gut microbiome composition (winter); LIHC cis rs6831352 0.918 rs13127582 chr4:100058194 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.69 -0.5 3.32e-23 Alcohol dependence; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs4332037 0.851 rs28728306 chr7:1961814 C/A cg23422044 chr7:1970798 MAD1L1 -0.64 -7.33 -0.37 1.71e-12 Bipolar disorder; LIHC cis rs116095464 0.614 rs28736753 chr5:274081 G/A cg22496380 chr5:211416 CCDC127 -0.98 -10.03 -0.48 6.22e-21 Breast cancer; LIHC trans rs875971 0.545 rs2279757 chr7:65828663 T/C cg26939375 chr7:64535504 NA 0.4 6.29 0.32 9.67e-10 Aortic root size; LIHC cis rs3762637 0.941 rs79493664 chr3:122109546 T/A cg24169773 chr3:122142474 KPNA1 -0.47 -9.16 -0.44 4.72e-18 LDL cholesterol levels; LIHC cis rs9303401 0.614 rs7215900 chr17:56654850 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.19 0.52 5.57e-25 Cognitive test performance; LIHC cis rs11711311 1.000 rs2603789 chr3:113470479 T/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.42 7.99 0.4 2.08e-14 IgG glycosylation; LIHC cis rs2073300 1.000 rs2236021 chr20:23432528 A/G cg12062639 chr20:23401060 NAPB 0.81 9.68 0.46 9.91e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs936229 0.749 rs8031937 chr15:75181121 A/G cg14664628 chr15:75095509 CSK -0.72 -9.63 -0.46 1.44e-19 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs7044106 0.791 rs10985009 chr9:123493039 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.77 -12.97 -0.57 1.48e-31 Hip circumference adjusted for BMI; LIHC cis rs1707322 0.721 rs11211166 chr1:46157942 G/A cg03146154 chr1:46216737 IPP 0.6 10.26 0.49 1.04e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12477438 0.520 rs11677247 chr2:99756358 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.82 0.65 1.12e-42 Chronic sinus infection; LIHC cis rs908922 0.676 rs525960 chr1:152497866 T/A cg23254163 chr1:152506842 NA 0.23 5.98 0.31 5.64e-9 Hair morphology; LIHC cis rs9527 0.615 rs11191489 chr10:104740568 C/A cg15744005 chr10:104629667 AS3MT -0.3 -6.18 -0.32 1.83e-9 Arsenic metabolism; LIHC cis rs7250872 0.606 rs2304616 chr19:1826164 G/T cg18850929 chr19:1828978 REXO1 0.39 6.29 0.32 9.44e-10 Bipolar disorder; LIHC cis rs9486715 0.838 rs9486275 chr6:96901187 C/T cg06623918 chr6:96969491 KIAA0776 0.84 14.61 0.62 6.92e-38 Headache; LIHC trans rs875971 0.660 rs10950044 chr7:66042976 A/G cg26939375 chr7:64535504 NA -0.43 -6.98 -0.35 1.52e-11 Aortic root size; LIHC cis rs74233809 1.000 rs1060240 chr10:104883337 A/G cg03493300 chr10:104813866 CNNM2 0.47 6.34 0.32 7.15e-10 Birth weight; LIHC cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg21970626 chr13:21893289 NA -0.37 -6.11 -0.31 2.76e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg18404041 chr3:52824283 ITIH1 0.59 9.94 0.47 1.31e-20 Bipolar disorder; LIHC cis rs898097 0.756 rs11655103 chr17:80813467 T/C cg15664640 chr17:80829946 TBCD -0.76 -12.53 -0.56 6.92e-30 Breast cancer; LIHC cis rs11031096 0.711 rs61899755 chr11:4201317 G/T cg18678763 chr11:4115507 RRM1 -0.41 -5.94 -0.31 6.88e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9818758 0.607 rs35060561 chr3:49255503 T/C cg00383909 chr3:49044727 WDR6 0.77 6.47 0.33 3.44e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11098499 0.913 rs35271032 chr4:120156659 C/T cg09307838 chr4:120376055 NA 0.75 10.9 0.51 5.9e-24 Corneal astigmatism; LIHC cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg11644478 chr21:40555479 PSMG1 0.84 10.57 0.5 8.49e-23 Cognitive function; LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg02990361 chr1:107599529 PRMT6 0.65 10.94 0.51 4.43e-24 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08706837 chr1:37940090 ZC3H12A -0.48 -6.2 -0.32 1.64e-9 Systolic blood pressure; LIHC trans rs75804782 0.521 rs58568091 chr2:239430582 G/A cg01134436 chr17:81009848 B3GNTL1 0.74 6.4 0.33 5.04e-10 Morning vs. evening chronotype;Chronotype; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25373372 chr6:82462656 FAM46A 0.38 6.1 0.31 2.84e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7223966 1.000 rs7220892 chr17:61908316 G/A cg05941027 chr17:61774174 LIMD2 0.35 7.47 0.37 6.81e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6062302 0.522 rs4809312 chr20:62234240 C/T cg16989086 chr20:62203971 PRIC285 0.57 8.23 0.41 3.97e-15 Glioblastoma; LIHC cis rs9457247 0.579 rs2181059 chr6:167441624 T/C cg23791538 chr6:167370224 RNASET2 -0.61 -10.55 -0.5 1.06e-22 Crohn's disease; LIHC cis rs600806 0.672 rs1144594 chr1:110029475 A/G cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.91 -0.3 8.15e-9 Intelligence (multi-trait analysis); LIHC cis rs12908161 1.000 rs58416181 chr15:85264461 G/A cg12863693 chr15:85201151 NMB 0.48 6.86 0.35 3.31e-11 Schizophrenia; LIHC cis rs9660992 0.573 rs1172147 chr1:205225457 G/A cg21545522 chr1:205238299 TMCC2 0.42 7.89 0.39 4.1e-14 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2120019 1.000 rs34237279 chr15:75361121 A/G cg06012730 chr15:75315579 PPCDC -0.35 -6.32 -0.32 7.99e-10 Blood trace element (Zn levels); LIHC cis rs6500602 0.701 rs8129 chr16:4562351 A/G cg08645402 chr16:4508243 NA 0.39 6.98 0.35 1.51e-11 Schizophrenia; LIHC cis rs12477438 0.871 rs13396584 chr2:99611768 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.98 12.42 0.56 1.67e-29 Chronic sinus infection; LIHC cis rs7119038 0.865 rs4938573 chr11:118741842 C/T cg19308663 chr11:118741387 NA -0.47 -6.13 -0.31 2.38e-9 Sjögren's syndrome; LIHC cis rs28475163 0.958 rs7395116 chr11:324880 C/G cg03071500 chr11:325964 NA 0.46 7.56 0.38 3.84e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs9649213 0.574 rs62479853 chr7:97917158 G/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.98 -0.31 5.65e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg22963979 chr7:1858916 MAD1L1 -0.44 -6.95 -0.35 1.8e-11 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.36 0.37 1.4e-12 Prudent dietary pattern; LIHC trans rs208520 0.526 rs7771233 chr6:66819784 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.04 -20.36 -0.74 6.4e-61 Exhaled nitric oxide output; LIHC cis rs4742903 0.935 rs10991168 chr9:106974902 C/T cg14250997 chr9:106856677 SMC2 0.35 5.83 0.3 1.32e-8 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs4718428 0.705 rs62465692 chr7:66295745 T/C cg10756647 chr7:56101905 PSPH 0.63 8.62 0.42 2.51e-16 Corneal structure; LIHC cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC cis rs11122272 0.677 rs2808615 chr1:231550171 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.7 11.14 0.52 8.66e-25 Hemoglobin concentration; LIHC cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.41 5.81 0.3 1.45e-8 Schizophrenia; LIHC cis rs5769765 0.825 rs7511620 chr22:50307932 T/C cg09182678 chr22:50328711 NA -0.43 -6.11 -0.31 2.72e-9 Schizophrenia; LIHC cis rs2224391 1.000 rs2224391 chr6:5260936 A/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.41 -6.07 -0.31 3.45e-9 Height; LIHC cis rs2580764 0.598 rs7340476 chr2:55227346 G/C cg09592903 chr2:55203963 RTN4 -0.69 -12.54 -0.56 5.98e-30 Mean platelet volume; LIHC cis rs10927875 0.562 rs10803401 chr1:16147377 G/A cg07117364 chr1:16154769 NA -0.39 -6.96 -0.35 1.77e-11 Dilated cardiomyopathy; LIHC cis rs709400 0.628 rs7154246 chr14:103876794 G/A cg26031613 chr14:104095156 KLC1 -0.72 -9.56 -0.46 2.48e-19 Body mass index; LIHC cis rs8078723 0.738 rs8066582 chr17:38146929 A/G cg17467752 chr17:38218738 THRA -0.58 -10.01 -0.48 7.69e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9399135 0.967 rs6923827 chr6:135335382 C/T cg22676075 chr6:135203613 NA 0.38 6.3 0.32 9.22e-10 Red blood cell count; LIHC cis rs651907 0.557 rs62284198 chr3:101474699 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.66 0.53 1.12e-26 Colorectal cancer; LIHC cis rs11758351 1.000 rs16891401 chr6:26202337 G/A cg16070018 chr6:26224392 HIST1H3E 0.56 6.67 0.34 1.06e-10 Gout;Renal underexcretion gout; LIHC cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg12463550 chr7:65579703 CRCP -0.68 -7.09 -0.36 7.77e-12 Diabetic kidney disease; LIHC cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg06453172 chr10:134556979 INPP5A -0.65 -9.05 -0.44 1.14e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs854572 0.600 rs705382 chr7:94955221 C/G cg21856205 chr7:94953877 PON1 -0.56 -9.46 -0.46 5e-19 Paraoxonase activity; LIHC cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg21724239 chr8:58056113 NA 0.48 6.36 0.33 6.53e-10 Developmental language disorder (linguistic errors); LIHC cis rs6088590 1.000 rs2295354 chr20:33356541 T/C cg06115741 chr20:33292138 TP53INP2 0.6 8.24 0.41 3.81e-15 Coronary artery disease; LIHC cis rs600806 0.850 rs4120621 chr1:109949008 A/G cg16275483 chr1:110013120 SYPL2 -0.47 -5.77 -0.3 1.78e-8 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg18252515 chr7:66147081 NA -1.26 -14.53 -0.62 1.32e-37 Diabetic kidney disease; LIHC cis rs7945718 0.592 rs6416153 chr11:12684263 A/G cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC trans rs1814175 0.791 rs10219223 chr11:49791468 A/T cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.48e-11 Height; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 21.25 0.75 1.7600000000000002e-64 Prudent dietary pattern; LIHC cis rs986417 1.000 rs2350900 chr14:60938681 T/A cg27398547 chr14:60952738 C14orf39 0.88 10.26 0.49 1.06e-21 Gut microbiota (bacterial taxa); LIHC cis rs7666738 0.830 rs2865989 chr4:99067532 G/A cg05340658 chr4:99064831 C4orf37 0.71 13.15 0.58 2.99e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg22800045 chr5:56110881 MAP3K1 0.67 8.65 0.42 2.06e-16 Initial pursuit acceleration; LIHC cis rs7772486 0.875 rs2224120 chr6:146343280 A/C cg05347473 chr6:146136440 FBXO30 0.37 5.99 0.31 5.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10254118 0.757 rs13241123 chr7:133135507 A/T cg10665199 chr7:133106180 EXOC4 0.53 8.19 0.4 5.39e-15 Intelligence (multi-trait analysis); LIHC cis rs4713118 0.597 rs172166 chr6:28020820 C/G cg16479474 chr6:28041457 NA 0.47 7.15 0.36 5.22e-12 Parkinson's disease; LIHC cis rs2204008 0.701 rs3898237 chr12:38219714 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.74 0.3 2.11e-8 Bladder cancer; LIHC cis rs17854409 0.536 rs3765464 chr20:61485236 T/C cg05147244 chr20:61493195 TCFL5 1.17 10.91 0.51 5.5e-24 Obesity-related traits; LIHC cis rs9733 0.596 rs72702570 chr1:150688196 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs950169 1.000 rs35297609 chr15:84772896 A/G cg17507749 chr15:85114479 UBE2QP1 0.76 7.75 0.39 1.03e-13 Schizophrenia; LIHC trans rs1499614 1.000 rs2659913 chr7:66157336 T/A cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs3008870 0.755 rs2815363 chr1:67497221 A/G cg02640540 chr1:67518911 SLC35D1 -0.44 -7.03 -0.36 1.13e-11 Lymphocyte percentage of white cells; LIHC cis rs151997 0.962 rs28090 chr5:50177509 T/C cg06027927 chr5:50259733 NA 0.57 7.59 0.38 3.05e-13 Callous-unemotional behaviour; LIHC cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg05368731 chr17:41323189 NBR1 0.73 12.63 0.56 2.82e-30 Menopause (age at onset); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg01812927 chr12:124901281 NCOR2 0.43 6.7 0.34 8.56e-11 Bilirubin levels; LIHC cis rs2153535 0.580 rs1414340 chr6:8491139 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs875971 0.638 rs6460305 chr7:66060408 G/A cg00343986 chr7:65444356 GUSB -0.38 -5.71 -0.3 2.45e-8 Aortic root size; LIHC cis rs7903847 0.642 rs10882915 chr10:99142184 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7927592 0.956 rs60212556 chr11:68305494 C/T cg16797656 chr11:68205561 LRP5 0.51 8.02 0.4 1.7e-14 Total body bone mineral density; LIHC trans rs1005277 0.579 rs2474587 chr10:38420666 C/T cg27523141 chr10:43048294 ZNF37B 0.37 6.47 0.33 3.32e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9359856 0.600 rs11961825 chr6:90482250 T/A cg13799429 chr6:90582589 CASP8AP2 -0.66 -5.86 -0.3 1.11e-8 Bipolar disorder; LIHC cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg11062466 chr8:58055876 NA 0.49 6.65 0.34 1.16e-10 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.735 rs62028423 chr15:76754514 G/A cg23625390 chr15:77176239 SCAPER -0.51 -8.54 -0.42 4.46e-16 Blood metabolite levels; LIHC cis rs703842 0.964 rs2014886 chr12:58177437 C/T cg18357645 chr12:58087776 OS9 -0.45 -6.98 -0.35 1.49e-11 Multiple sclerosis; LIHC cis rs7903847 0.642 rs9888117 chr10:99159963 C/G cg06359132 chr10:99160096 RRP12 -0.41 -6.43 -0.33 4.26e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs992157 0.764 rs2891077 chr2:219184430 A/C cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.15 0.48 2.48e-21 Colorectal cancer; LIHC cis rs7613875 0.600 rs2856237 chr3:50158774 A/G cg21467203 chr3:49911342 NA 0.5 9.0 0.44 1.63e-17 Body mass index; LIHC cis rs8044868 0.530 rs2288000 chr16:72058881 A/G cg01557791 chr16:72042693 DHODH -0.4 -6.72 -0.34 7.74e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs7512552 0.646 rs1694367 chr1:150329469 T/A cg15654264 chr1:150340011 RPRD2 0.69 11.33 0.52 1.78e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs929354 0.713 rs3802130 chr7:156965237 A/G cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22828147 chr6:4776490 CDYL 0.43 6.52 0.33 2.54e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7927771 0.770 rs11039203 chr11:47384597 A/G cg20135002 chr11:47629003 NA -0.51 -8.75 -0.43 9.91e-17 Subjective well-being; LIHC cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg18357526 chr6:26021779 HIST1H4A -0.58 -8.18 -0.4 5.57e-15 Blood metabolite levels; LIHC cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg07424592 chr7:64974309 NA 0.79 9.19 0.44 4.01e-18 Diabetic kidney disease; LIHC cis rs2180341 0.782 rs6912552 chr6:127722946 C/G cg24812749 chr6:127587940 RNF146 -0.78 -11.72 -0.54 6.46e-27 Breast cancer; LIHC cis rs10489202 0.909 rs61809580 chr1:168091602 A/C cg24449463 chr1:168025552 DCAF6 -0.5 -6.23 -0.32 1.34e-9 Schizophrenia; LIHC cis rs9486719 1.000 rs10872018 chr6:97026429 G/A cg06623918 chr6:96969491 KIAA0776 -0.71 -7.25 -0.36 2.82e-12 Migraine;Coronary artery disease; LIHC cis rs919433 0.783 rs55725278 chr2:198238223 C/T cg03934865 chr2:198174659 NA 0.57 8.76 0.43 9.31e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs4566357 0.576 rs3769644 chr2:227917240 C/G cg16088116 chr21:44841560 SIK1 -0.42 -6.52 -0.33 2.59e-10 Coronary artery disease; LIHC cis rs9486715 0.867 rs4839842 chr6:96955387 A/T cg06623918 chr6:96969491 KIAA0776 0.86 15.21 0.64 2.93e-40 Headache; LIHC cis rs243505 0.660 rs3807450 chr7:148522269 C/A cg09806900 chr7:148480153 CUL1 0.43 6.12 0.31 2.59e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12936587 0.535 rs6502615 chr17:17612023 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.45 -7.39 -0.37 1.13e-12 Hip circumference;Coronary artery disease or large artery stroke;Coronary heart disease;Coronary artery disease; LIHC trans rs2727020 0.701 rs7949044 chr11:49597334 C/T cg15704280 chr7:45808275 SEPT13 -0.83 -13.27 -0.58 1.01e-32 Coronary artery disease; LIHC cis rs2635047 0.638 rs2684840 chr18:44737230 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.42 5.87 0.3 1.05e-8 Educational attainment; LIHC trans rs4927850 1.000 rs7630875 chr3:195753766 A/G cg16724585 chr3:197361211 NA -0.48 -6.77 -0.34 5.65e-11 Pancreatic cancer; LIHC cis rs72781680 0.611 rs7596820 chr2:24335036 G/C cg06627628 chr2:24431161 ITSN2 -0.66 -7.74 -0.39 1.16e-13 Lymphocyte counts; LIHC cis rs986417 1.000 rs10144805 chr14:60927652 T/C cg27398547 chr14:60952738 C14orf39 0.81 9.56 0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs10883723 0.962 rs1056739 chr10:104236542 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 11.37 0.52 1.22e-25 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7412746 0.552 rs4970980 chr1:150864992 A/C cg15448220 chr1:150897856 SETDB1 0.38 6.09 0.31 2.98e-9 Melanoma; LIHC trans rs1814175 0.817 rs4405313 chr11:50013636 G/A cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.45 7.78 0.39 8.78e-14 Height; LIHC cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg24209194 chr3:40518798 ZNF619 -0.44 -6.27 -0.32 1.09e-9 Renal cell carcinoma; LIHC cis rs6570726 0.791 rs9403734 chr6:145931459 C/G cg13319975 chr6:146136371 FBXO30 -0.42 -6.56 -0.33 2e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Bipolar disorder; LIHC cis rs7619427 0.908 rs7617917 chr3:44081434 G/A cg24966902 chr3:44043705 NA 0.42 6.09 0.31 3e-9 Schizophrenia; LIHC cis rs2228479 0.850 rs17226512 chr16:89839976 T/C cg06558623 chr16:89946397 TCF25 0.84 11.66 0.53 1.09e-26 Skin colour saturation; LIHC cis rs644799 0.544 rs1622515 chr11:95523433 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.64 9.29 0.45 1.86e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg18404041 chr3:52824283 ITIH1 -0.51 -8.56 -0.42 3.8e-16 Bipolar disorder; LIHC cis rs36051895 0.559 rs12342390 chr9:5211297 G/A cg02405213 chr9:5042618 JAK2 -0.6 -10.26 -0.49 1.03e-21 Pediatric autoimmune diseases; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.73 10.81 0.5 1.29e-23 Lymphocyte counts; LIHC cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg17328964 chr8:145687451 CYHR1 0.37 5.92 0.3 7.76e-9 Age at first birth; LIHC cis rs12188164 0.543 rs2672757 chr5:454732 A/G cg26076054 chr5:421317 AHRR 0.27 5.94 0.31 6.88e-9 Cystic fibrosis severity; LIHC cis rs17376456 1.000 rs13154249 chr5:93550508 C/T cg25358565 chr5:93447407 FAM172A 1.08 9.8 0.47 3.72e-20 Diabetic retinopathy; LIHC cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg26818010 chr10:134567672 INPP5A -0.79 -9.64 -0.46 1.28e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg27170947 chr2:26402098 FAM59B 0.65 8.36 0.41 1.64e-15 Gut microbiome composition (summer); LIHC cis rs713477 0.967 rs6573029 chr14:55913550 A/C cg13175173 chr14:55914753 NA -0.34 -8.06 -0.4 1.33e-14 Pediatric bone mineral content (femoral neck); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01353569 chr7:106810328 HBP1 0.4 6.4 0.33 5.12e-10 Cognitive function; LIHC trans rs7618501 1.000 rs60205400 chr3:49800272 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.81 15.13 0.63 6.04e-40 Intelligence (multi-trait analysis); LIHC cis rs78456975 0.941 rs13423300 chr2:1553809 C/A cg01028140 chr2:1542097 TPO -0.52 -5.97 -0.31 5.83e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs7224737 1.000 rs9889618 chr17:40293467 C/T cg02450064 chr17:40260053 DHX58 -0.3 -6.15 -0.32 2.17e-9 Fibrinogen levels; LIHC cis rs1113500 0.836 rs1618973 chr1:108586767 T/C cg06207961 chr1:108661230 NA -0.37 -7.13 -0.36 5.82e-12 Growth-regulated protein alpha levels; LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.35 0.37 1.51e-12 Prudent dietary pattern; LIHC cis rs1570989 0.841 rs9349054 chr6:12029312 C/T cg17804551 chr6:12015979 HIVEP1 -0.41 -6.26 -0.32 1.14e-9 Alcohol and nicotine co-dependence; LIHC cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg03264133 chr6:25882463 NA -0.68 -8.84 -0.43 5.19e-17 Intelligence (multi-trait analysis); LIHC cis rs477692 0.637 rs10829598 chr10:131319774 C/G cg19680672 chr10:131412579 MGMT -0.38 -5.8 -0.3 1.49e-8 Response to temozolomide; LIHC cis rs9905704 0.671 rs4337355 chr17:56950920 C/T cg05425664 chr17:57184151 TRIM37 -0.45 -6.24 -0.32 1.3e-9 Testicular germ cell tumor; LIHC cis rs2455799 0.533 rs2470513 chr3:15750056 G/A cg12698662 chr3:15914712 MIR563 -0.39 -7.23 -0.36 3.12e-12 Mean platelet volume; LIHC cis rs644799 0.710 rs11021311 chr11:95505227 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.26 0.58 1.16e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs60871478 0.588 rs6952577 chr7:872100 C/T cg05535760 chr7:792225 HEATR2 0.77 6.54 0.33 2.24e-10 Cerebrospinal P-tau181p levels; LIHC cis rs11971779 0.715 rs7779390 chr7:139112953 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.29 0.49 8.39e-22 Diisocyanate-induced asthma; LIHC cis rs9596863 1.000 rs1545659 chr13:54433788 G/A ch.13.53330881F chr13:54432880 NA -0.45 -6.43 -0.33 4.18e-10 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs904251 0.861 rs1757173 chr6:37486952 A/C cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.47e-9 Cognitive performance; LIHC cis rs7100689 0.516 rs3862532 chr10:82015725 A/C cg00277334 chr10:82204260 NA -0.51 -6.37 -0.33 6.11e-10 Post bronchodilator FEV1; LIHC cis rs861020 0.771 rs674804 chr1:210014603 C/G cg09163369 chr1:210001066 C1orf107 0.52 6.71 0.34 7.93e-11 Orofacial clefts; LIHC cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg06238570 chr21:40685208 BRWD1 0.62 7.51 0.38 5.29e-13 Cognitive function; LIHC cis rs11690935 1.000 rs6433311 chr2:172549248 A/G cg13550731 chr2:172543902 DYNC1I2 0.94 19.26 0.72 1.66e-56 Schizophrenia; LIHC cis rs2412488 0.815 rs13150384 chr4:54357457 T/A cg22241045 chr4:54363911 LNX1 0.41 6.61 0.34 1.44e-10 DNA methylation (variation); LIHC cis rs9309473 0.607 rs58962779 chr2:73555801 T/C cg20560298 chr2:73613845 ALMS1 -0.41 -6.43 -0.33 4.32e-10 Metabolite levels; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg07725925 chr16:89976287 TCF25 -0.4 -5.82 -0.3 1.33e-8 Skin colour saturation; LIHC cis rs7487075 0.780 rs10785624 chr12:46766787 C/T cg21428710 chr12:47219797 SLC38A4 0.28 5.92 0.31 7.71e-9 Itch intensity from mosquito bite; LIHC cis rs2637266 0.626 rs846619 chr10:78545449 A/G cg18941641 chr10:78392320 NA 0.3 6.37 0.33 6.08e-10 Pulmonary function; LIHC cis rs12142240 0.698 rs72677594 chr1:46824371 A/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs763121 0.853 rs6519120 chr22:38991393 A/C cg14440974 chr22:39074834 NA 0.42 6.65 0.34 1.13e-10 Menopause (age at onset); LIHC cis rs7903847 0.596 rs11189203 chr10:99159096 C/A cg06359132 chr10:99160096 RRP12 -0.4 -6.22 -0.32 1.45e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg00280220 chr17:61926910 NA 0.41 6.27 0.32 1.09e-9 Prudent dietary pattern; LIHC cis rs7666738 0.546 rs28590002 chr4:98722642 C/T cg05340658 chr4:99064831 C4orf37 0.5 6.64 0.34 1.25e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs2274273 0.967 rs8013027 chr14:55610940 C/G cg01864836 chr14:55583639 NA -0.39 -7.25 -0.37 2.76e-12 Protein biomarker; LIHC cis rs1419980 0.673 rs7296837 chr12:7757832 A/G cg10578777 chr12:7781093 NA 0.49 8.75 0.43 9.76e-17 HDL cholesterol levels; LIHC trans rs4843747 0.671 rs8062855 chr16:88106941 T/C cg09572067 chr16:29127029 RRN3P2 0.51 8.06 0.4 1.3e-14 Menopause (age at onset); LIHC cis rs826838 0.933 rs1906263 chr12:38653362 T/C cg26384229 chr12:38710491 ALG10B 1.07 14.56 0.62 1.06e-37 Heart rate; LIHC cis rs7903847 0.642 rs7078782 chr10:99168604 C/T cg08345082 chr10:99160200 RRP12 -0.4 -7.06 -0.36 9.47e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs2073300 1.000 rs79169006 chr20:23443535 A/T cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7412746 0.566 rs11204743 chr1:150890406 A/T cg15448220 chr1:150897856 SETDB1 0.45 7.03 0.36 1.13e-11 Melanoma; LIHC cis rs1559088 1.000 rs7256328 chr19:33558705 G/C cg17764715 chr19:33622953 WDR88 0.41 5.79 0.3 1.61e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2857078 0.720 rs9901595 chr17:42305699 G/A cg13607699 chr17:42295918 UBTF 0.65 11.63 0.53 1.39e-26 Red cell distribution width;Reticulocyte count; LIHC cis rs4474465 0.850 rs10793322 chr11:78242615 T/C cg02023728 chr11:77925099 USP35 -0.33 -5.86 -0.3 1.09e-8 Alzheimer's disease (survival time); LIHC cis rs7520050 0.966 rs1707340 chr1:46514942 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.93 0.31 7.49e-9 Red blood cell count;Reticulocyte count; LIHC cis rs61041384 0.661 rs74240768 chr12:123683976 T/C cg00376283 chr12:123451042 ABCB9 -0.55 -6.14 -0.32 2.28e-9 Schizophrenia; LIHC cis rs12908161 0.960 rs62019463 chr15:85288087 G/A cg12863693 chr15:85201151 NMB 0.44 6.31 0.32 8.81e-10 Schizophrenia; LIHC cis rs1499614 0.901 rs2178742 chr7:66197799 G/A cg18252515 chr7:66147081 NA -1.36 -18.54 -0.71 1.3e-53 Gout; LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg11062466 chr8:58055876 NA 0.49 7.25 0.37 2.78e-12 Developmental language disorder (linguistic errors); LIHC cis rs651907 0.514 rs34301719 chr3:101417993 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 11.82 0.54 2.99e-27 Colorectal cancer; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg07677032 chr17:61819896 STRADA 0.44 6.55 0.33 2.09e-10 Prudent dietary pattern; LIHC cis rs15676 0.947 rs2977994 chr9:131585216 G/T cg00228799 chr9:131580591 ENDOG 0.47 7.15 0.36 5.46e-12 Blood metabolite levels; LIHC cis rs801193 1.000 rs2286684 chr7:66129830 G/T cg11764359 chr7:65958608 NA -0.71 -10.55 -0.5 1.05e-22 Aortic root size; LIHC cis rs3960554 0.660 rs55671363 chr7:75793405 T/C cg16684958 chr7:75615977 POR 0.44 6.67 0.34 1.05e-10 Eotaxin levels; LIHC cis rs908922 0.676 rs4845443 chr1:152507156 C/T cg23254163 chr1:152506842 NA 0.24 6.23 0.32 1.34e-9 Hair morphology; LIHC cis rs9467773 0.596 rs62396201 chr6:26668216 G/A cg09904177 chr6:26538194 HMGN4 0.53 10.32 0.49 6.35e-22 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg11494091 chr17:61959527 GH2 0.45 8.37 0.41 1.55e-15 Prudent dietary pattern; LIHC cis rs1059312 0.808 rs2306683 chr12:129299675 C/G cg09035930 chr12:129282057 SLC15A4 0.6 11.19 0.52 5.83e-25 Systemic lupus erythematosus; LIHC cis rs9814567 1.000 rs3846056 chr3:134227292 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.95 -0.31 6.7e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2617583 0.967 rs2652509 chr5:1448247 A/G cg07151155 chr5:1473589 LPCAT1 -0.37 -5.8 -0.3 1.48e-8 Breast cancer; LIHC cis rs2070488 0.699 rs6599205 chr3:38529440 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.64 9.92 0.47 1.48e-20 Electrocardiographic conduction measures; LIHC cis rs79149102 0.579 rs76900720 chr15:75348895 A/T cg16226627 chr15:75307476 SCAMP5 0.52 8.84 0.43 5.23e-17 Lung cancer; LIHC cis rs11675119 0.517 rs12619851 chr2:3492747 T/C cg15541040 chr2:3486749 NA -0.43 -6.49 -0.33 2.94e-10 Neurofibrillary tangles; LIHC trans rs9641123 0.639 rs2251307 chr7:93207036 A/G cg09745688 chr16:2908918 PRSS22 -0.37 -6.43 -0.33 4.22e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs3796352 1.000 rs11710707 chr3:52975916 A/G cg07884673 chr3:53033167 SFMBT1 0.89 6.49 0.33 3.1e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2304069 0.954 rs6861548 chr5:149384680 A/G cg12661370 chr5:149340060 SLC26A2 0.51 6.18 0.32 1.8e-9 HIV-1 control; LIHC cis rs1997103 0.906 rs6593232 chr7:55402916 C/T cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7312933 0.584 rs7974654 chr12:42630466 C/A cg17420585 chr12:42539391 GXYLT1 -0.36 -5.84 -0.3 1.23e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs367615 0.552 rs10042721 chr5:108713970 C/T cg17395555 chr5:108820864 NA -0.29 -6.22 -0.32 1.43e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.25 0.32 1.24e-9 Schizophrenia; LIHC cis rs6963495 0.818 rs6961233 chr7:105150469 C/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs875971 0.660 rs7807944 chr7:66087195 C/G cg18876405 chr7:65276391 NA -0.44 -7.8 -0.39 7.5e-14 Aortic root size; LIHC cis rs7552404 0.924 rs1694419 chr1:76219801 C/T cg03433033 chr1:76189801 ACADM 0.66 10.11 0.48 3.4e-21 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2108622 0.727 rs62107770 chr19:15985425 A/G cg13772218 chr19:15982569 NA 0.37 7.57 0.38 3.48e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs317689 0.513 rs317678 chr12:69692166 C/G cg22834771 chr12:69754056 YEATS4 -0.39 -6.38 -0.33 5.79e-10 Response to diuretic therapy; LIHC cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg10802521 chr3:52805072 NEK4 -0.46 -7.84 -0.39 5.94e-14 Electroencephalogram traits; LIHC trans rs9475752 0.564 rs7744799 chr6:56743843 C/T cg25726699 chr6:135826776 C6orf217 0.41 6.16 0.32 2.05e-9 Menarche (age at onset); LIHC cis rs10751667 0.666 rs10902255 chr11:967268 T/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs6456156 0.526 rs1854853 chr6:167533062 A/G cg23791538 chr6:167370224 RNASET2 0.43 7.12 0.36 6.48e-12 Primary biliary cholangitis; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.0 0.58 1.11e-31 Prudent dietary pattern; LIHC cis rs7523273 0.526 rs2745980 chr1:208018367 A/C cg22525895 chr1:207977042 MIR29B2 0.57 9.33 0.45 1.34e-18 Schizophrenia; LIHC cis rs7959452 0.590 rs11177628 chr12:69765421 G/A cg14784868 chr12:69753453 YEATS4 0.95 20.5 0.74 1.68e-61 Blood protein levels; LIHC cis rs2832191 0.791 rs9983651 chr21:30491227 T/A cg24692254 chr21:30365293 RNF160 -0.6 -10.47 -0.49 1.94e-22 Dental caries; LIHC cis rs4718428 0.607 rs66954441 chr7:66369209 T/C cg18252515 chr7:66147081 NA -0.69 -9.54 -0.46 2.69e-19 Corneal structure; LIHC cis rs3768617 0.811 rs12138053 chr1:182979560 C/T ch.1.3577855R chr1:183094577 LAMC1 0.47 7.29 0.37 2.15e-12 Fuchs's corneal dystrophy; LIHC cis rs12478296 0.685 rs12473450 chr2:242991746 C/T cg18898632 chr2:242989856 NA -0.47 -6.68 -0.34 9.56e-11 Obesity-related traits; LIHC cis rs4975616 0.773 rs414965 chr5:1324121 G/A cg06550200 chr5:1325588 CLPTM1L -0.64 -10.12 -0.48 3.12e-21 Lung cancer; LIHC cis rs8062405 0.789 rs1968752 chr16:28631585 G/T cg07451762 chr16:28383216 NA 0.36 6.21 0.32 1.56e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6424115 0.760 rs2999566 chr1:24051124 A/G cg10978503 chr1:24200527 CNR2 0.29 6.94 0.35 2.01e-11 Immature fraction of reticulocytes; LIHC cis rs6565180 1.000 rs11863150 chr16:30385503 C/T cg17640201 chr16:30407289 ZNF48 0.75 13.07 0.58 6.06e-32 Tonsillectomy; LIHC cis rs1419980 0.673 rs7296837 chr12:7757832 A/G cg25828445 chr12:7781288 NA 0.44 6.75 0.34 6.36e-11 HDL cholesterol levels; LIHC cis rs9911578 1.000 rs12602346 chr17:56901713 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.83 -0.43 5.44e-17 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg23131131 chr22:24373011 LOC391322 -0.69 -9.97 -0.47 9.86e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7100689 0.622 rs4933378 chr10:82147057 T/C cg00277334 chr10:82204260 NA -0.58 -7.53 -0.38 4.6e-13 Post bronchodilator FEV1; LIHC cis rs11792861 0.781 rs2297581 chr9:111755008 C/T cg05043794 chr9:111880884 C9orf5 -0.32 -7.33 -0.37 1.7e-12 Menarche (age at onset); LIHC cis rs8062405 1.000 rs7187776 chr16:28857645 A/G cg00204512 chr16:28754710 NA 0.29 5.75 0.3 1.97e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg18306943 chr3:40428807 ENTPD3 -0.4 -7.29 -0.37 2.14e-12 Renal cell carcinoma; LIHC cis rs9467160 0.520 rs9379660 chr6:24441635 C/G cg20631270 chr6:24437470 GPLD1 0.43 6.62 0.34 1.42e-10 Liver enzyme levels; LIHC cis rs10540 0.730 rs61876338 chr11:493730 A/G cg03576123 chr11:487126 PTDSS2 -1.16 -8.65 -0.42 2.07e-16 Body mass index; LIHC cis rs7615952 0.932 rs7629977 chr3:125649573 T/G cg05084668 chr3:125655381 ALG1L -0.57 -8.18 -0.4 5.49e-15 Blood pressure (smoking interaction); LIHC cis rs910316 0.737 rs175043 chr14:75471803 G/A cg08847533 chr14:75593920 NEK9 -0.88 -17.69 -0.69 3.63e-50 Height; LIHC cis rs2303759 0.709 rs10414921 chr19:49823047 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.53 7.89 0.39 4.02e-14 Multiple sclerosis; LIHC trans rs1728785 1.000 rs1170439 chr16:68608511 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.58 7.01 0.35 1.29e-11 Ulcerative colitis; LIHC cis rs6570726 0.935 rs411641 chr6:145827532 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg23172400 chr8:95962367 TP53INP1 -0.42 -9.79 -0.47 4.01e-20 Type 2 diabetes; LIHC cis rs13161895 1.000 rs12656814 chr5:179471556 G/A cg02702477 chr5:179499311 RNF130 0.8 11.17 0.52 6.67e-25 LDL cholesterol; LIHC cis rs1005277 0.579 rs2474595 chr10:38426782 C/G cg00409905 chr10:38381863 ZNF37A 0.62 10.89 0.51 6.47e-24 Extrinsic epigenetic age acceleration; LIHC cis rs798554 0.757 rs1182172 chr7:2878103 G/A cg19717773 chr7:2847554 GNA12 -0.42 -6.16 -0.32 1.99e-9 Height; LIHC cis rs616402 0.564 rs602601 chr1:10567058 C/T cg17425144 chr1:10567563 PEX14 0.63 13.11 0.58 4.31e-32 Breast size; LIHC cis rs8044995 0.563 rs7500163 chr16:68364358 C/G cg05110241 chr16:68378359 PRMT7 -0.92 -10.38 -0.49 4.13e-22 Schizophrenia; LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs933688 1.000 rs6862125 chr5:90724598 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.87 18.31 0.7 1.07e-52 Smoking behavior; LIHC cis rs77861329 1.000 rs352149 chr3:52209530 C/A cg08692210 chr3:52188851 WDR51A 0.83 7.96 0.4 2.61e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs9980664 0.591 rs58886971 chr21:34678942 G/A cg04842828 chr21:34696676 IFNAR1 0.48 5.89 0.3 9.09e-9 Cognitive decline (age-related); LIHC cis rs2408955 0.521 rs1476607 chr12:48524804 A/G cg21466736 chr12:48725269 NA 0.63 9.01 0.44 1.43e-17 Glycated hemoglobin levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23861889 chr2:45878066 PRKCE 0.44 6.04 0.31 4.02e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs950169 0.922 rs6603022 chr15:84830170 T/C cg12863693 chr15:85201151 NMB -0.4 -5.86 -0.3 1.08e-8 Schizophrenia; LIHC cis rs600806 0.713 rs10857786 chr1:110010110 C/G cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.8 -0.39 7.43e-14 Intelligence (multi-trait analysis); LIHC cis rs9399135 0.967 rs9389254 chr6:135330709 C/T cg24558204 chr6:135376177 HBS1L 0.42 6.96 0.35 1.72e-11 Red blood cell count; LIHC cis rs9814567 1.000 rs4423809 chr3:134300107 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.88 0.3 9.6e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg06951627 chr6:26196580 NA 0.55 6.43 0.33 4.39e-10 Gout;Renal underexcretion gout; LIHC cis rs2354432 0.607 rs1890039 chr1:146681951 T/C cg25205988 chr1:146714368 CHD1L 0.98 6.47 0.33 3.34e-10 Mitochondrial DNA levels; LIHC cis rs6565189 0.865 rs4500746 chr16:30504344 T/C cg17640201 chr16:30407289 ZNF48 0.54 6.23 0.32 1.37e-9 Tonsillectomy; LIHC trans rs6928977 0.660 rs12203875 chr6:135860414 C/T cg15153026 chr7:143058944 FAM131B -0.42 -6.13 -0.31 2.38e-9 Nodular sclerosis Hodgkin lymphoma;Hodgkin's lymphoma; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.72 11.66 0.53 1.09e-26 Prudent dietary pattern; LIHC cis rs17106184 1.000 rs72900957 chr1:51145808 A/G cg07174182 chr1:51127561 FAF1 -0.61 -6.54 -0.33 2.25e-10 Type 2 diabetes; LIHC cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg24549020 chr5:56110836 MAP3K1 0.52 6.69 0.34 9.28e-11 Initial pursuit acceleration; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg19226647 chr10:114710611 TCF7L2 -0.48 -6.7 -0.34 8.64e-11 Migraine with aura; LIHC cis rs273218 0.724 rs392714 chr5:53382703 C/T ch.5.1024479R chr5:53302184 ARL15 0.52 8.43 0.41 9.87e-16 Migraine; LIHC cis rs2842992 0.513 rs7759086 chr6:160193853 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.98 0.44 1.83e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs11098499 0.863 rs1480936 chr4:120462861 C/T cg09307838 chr4:120376055 NA 0.76 11.6 0.53 1.88e-26 Corneal astigmatism; LIHC cis rs644799 1.000 rs10831431 chr11:95510089 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.54e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.91 8.84 0.43 5.14e-17 Platelet count; LIHC cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.36 0.37 1.34e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23104823 chr14:45553408 PRPF39 0.39 6.51 0.33 2.68e-10 Cognitive function; LIHC cis rs1577917 1.000 rs12199784 chr6:86726808 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.9 -0.35 2.54e-11 Response to antipsychotic treatment; LIHC cis rs250677 0.687 rs42364 chr5:148438858 T/A cg18129178 chr5:148520854 ABLIM3 -0.48 -7.48 -0.38 6.18e-13 Breast cancer; LIHC cis rs250677 0.617 rs166106 chr5:148447061 T/C cg23229984 chr5:148520753 ABLIM3 0.49 5.72 0.3 2.39e-8 Breast cancer; LIHC cis rs6088590 0.603 rs6579186 chr20:33282198 G/C cg24642439 chr20:33292090 TP53INP2 0.49 6.81 0.35 4.38e-11 Coronary artery disease; LIHC cis rs921968 0.541 rs7574429 chr2:219498759 T/G cg02985541 chr2:219472218 PLCD4 0.42 6.63 0.34 1.3e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1801251 1.000 rs3816334 chr2:233708806 A/G cg08000102 chr2:233561755 GIGYF2 -0.76 -11.51 -0.53 3.76e-26 Coronary artery disease; LIHC cis rs7027203 0.828 rs10761287 chr9:96609150 A/G cg13679303 chr9:96623674 NA -0.3 -6.65 -0.34 1.15e-10 DNA methylation (variation); LIHC cis rs1801251 1.000 rs283469 chr2:233656997 G/T cg25237894 chr2:233734115 C2orf82 0.58 11.32 0.52 1.93e-25 Coronary artery disease; LIHC cis rs10411936 0.712 rs3810198 chr19:16601194 C/T cg10248733 chr19:16607483 C19orf44;CALR3 0.52 6.91 0.35 2.32e-11 White blood cell count;Multiple sclerosis; LIHC cis rs2758596 0.826 rs2758606 chr1:156201920 G/A cg24450063 chr1:156163899 SLC25A44 1.0 10.59 0.5 7.7e-23 Paclitaxel disposition in epithelial ovarian cancer; LIHC trans rs61931739 0.500 rs7306053 chr12:34510848 T/G cg26384229 chr12:38710491 ALG10B 0.63 8.12 0.4 8.29e-15 Morning vs. evening chronotype; LIHC cis rs2842992 0.768 rs2273824 chr6:160211445 C/T cg11366901 chr6:160182831 ACAT2 0.86 14.38 0.61 5.22e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs60871478 0.636 rs7792072 chr7:886239 C/T cg05535760 chr7:792225 HEATR2 -0.81 -6.59 -0.34 1.63e-10 Cerebrospinal P-tau181p levels; LIHC cis rs2741335 0.876 rs2565055 chr8:27337380 G/T cg07150473 chr8:27338183 CHRNA2 -0.47 -6.67 -0.34 1.02e-10 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC cis rs801193 1.000 rs62466794 chr7:66191579 G/A cg14393609 chr7:65229607 NA 0.36 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs6831352 0.918 rs7689753 chr4:100055575 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7940866 0.801 rs2113928 chr11:130835975 A/G cg12179176 chr11:130786555 SNX19 0.59 8.57 0.42 3.56e-16 Schizophrenia; LIHC cis rs2204008 0.806 rs7305409 chr12:38349133 G/A cg26384229 chr12:38710491 ALG10B 0.87 10.79 0.5 1.54e-23 Bladder cancer; LIHC cis rs7843479 0.601 rs4872204 chr8:21841396 T/C cg17168535 chr8:21777572 XPO7 0.58 10.38 0.49 4.09e-22 Mean corpuscular volume; LIHC cis rs2978263 0.628 rs1010054 chr8:30309947 C/T cg05780722 chr8:30327988 RBPMS 0.32 6.13 0.31 2.49e-9 Cognitive performance; LIHC trans rs2727020 0.681 rs1976901 chr11:49378697 T/C cg15704280 chr7:45808275 SEPT13 -0.93 -17.61 -0.69 7.14e-50 Coronary artery disease; LIHC cis rs7927592 0.913 rs2282563 chr11:68333200 C/T cg20283391 chr11:68216788 NA -0.52 -7.72 -0.39 1.28e-13 Total body bone mineral density; LIHC cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg08645402 chr16:4508243 NA 0.41 7.19 0.36 4.1e-12 Schizophrenia; LIHC cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg11644478 chr21:40555479 PSMG1 0.77 9.68 0.46 9.51e-20 Cognitive function; LIHC cis rs6582630 0.555 rs11182193 chr12:38474090 C/G cg26384229 chr12:38710491 ALG10B 0.66 9.13 0.44 6.3e-18 Drug-induced liver injury (flucloxacillin); LIHC cis rs317689 0.718 rs645026 chr12:69757931 G/A cg19645103 chr12:69753606 YEATS4 -0.46 -6.32 -0.32 8.13e-10 Response to diuretic therapy; LIHC cis rs6690583 0.524 rs6680422 chr1:85451945 C/T cg22153463 chr1:85462885 MCOLN2 0.52 6.24 0.32 1.32e-9 Serum sulfate level; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg18110333 chr6:292329 DUSP22 -0.54 -7.22 -0.36 3.41e-12 Menopause (age at onset); LIHC cis rs7927592 0.913 rs10896347 chr11:68353127 G/A cg01657329 chr11:68192670 LRP5 -0.48 -6.22 -0.32 1.46e-9 Total body bone mineral density; LIHC cis rs7246657 0.943 rs1015848 chr19:37945274 A/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg02353165 chr6:42928485 GNMT 0.96 15.52 0.64 1.69e-41 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs929354 0.742 rs62491945 chr7:156955580 G/A cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09071838 chr13:25497213 CENPJ 0.45 6.85 0.35 3.47e-11 Lung function (FEV1/FVC); LIHC cis rs5417 0.775 rs222852 chr17:7140606 A/G cg14660024 chr17:7154518 C17orf81;DULLARD -0.42 -7.92 -0.39 3.44e-14 Diastolic blood pressure; LIHC cis rs16854884 0.683 rs2053211 chr3:143774592 C/T cg06585982 chr3:143692056 C3orf58 -0.45 -6.37 -0.33 5.93e-10 Economic and political preferences (feminism/equality); LIHC cis rs1577917 0.655 rs2842605 chr6:86335150 A/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.23 -0.32 1.35e-9 Response to antipsychotic treatment; LIHC cis rs597539 0.652 rs569777 chr11:68706848 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.25 0.48 1.14e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs912057 0.833 rs1024245 chr6:6743319 A/G cg06612196 chr6:6737390 NA 0.53 9.98 0.48 9.08e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs1198430 0.925 rs2811975 chr1:23801081 A/T cg13183780 chr1:23809682 ASAP3 -0.56 -7.9 -0.39 3.86e-14 Total cholesterol levels; LIHC cis rs2991971 0.810 rs2036021 chr1:45901370 G/A cg24296786 chr1:45957014 TESK2 0.51 7.93 0.39 3.15e-14 High light scatter reticulocyte count; LIHC cis rs12142240 0.698 rs72677593 chr1:46824363 T/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs4665809 1.000 rs12471809 chr2:26307140 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -9.02 -0.44 1.34e-17 Gut microbiome composition (summer); LIHC cis rs13108904 0.875 rs1564509 chr4:1236562 C/G cg20887711 chr4:1340912 KIAA1530 0.46 7.04 0.36 1.05e-11 Obesity-related traits; LIHC cis rs3824867 0.920 rs7130693 chr11:47452321 T/C cg20307385 chr11:47447363 PSMC3 -0.58 -7.96 -0.4 2.62e-14 Mean corpuscular hemoglobin; LIHC cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg07061783 chr6:25882402 NA 0.67 8.87 0.43 4.23e-17 Blood metabolite levels; LIHC cis rs763014 0.932 rs35067229 chr16:649638 T/C cg09263875 chr16:632152 PIGQ 0.58 10.64 0.5 5.14e-23 Height; LIHC cis rs2115536 0.730 rs12898642 chr15:80182050 T/C cg11839771 chr15:80205821 ST20 -0.28 -5.73 -0.3 2.25e-8 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs6456156 0.565 rs6921588 chr6:167494397 G/T cg12798992 chr6:167411361 FGFR1OP 0.46 6.9 0.35 2.51e-11 Primary biliary cholangitis; LIHC cis rs9457247 0.905 rs444210 chr6:167390242 A/G cg23791538 chr6:167370224 RNASET2 -0.71 -12.94 -0.57 1.89e-31 Crohn's disease; LIHC cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg20278634 chr1:36274212 EIF2C4 0.4 6.1 0.31 2.89e-9 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC trans rs116095464 0.614 rs78905930 chr5:246560 G/A cg00938859 chr5:1591904 SDHAP3 0.59 7.22 0.36 3.33e-12 Breast cancer; LIHC cis rs1577917 0.959 rs34258068 chr6:86679449 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.55 -0.33 2.1e-10 Response to antipsychotic treatment; LIHC cis rs12368653 0.591 rs1552842 chr12:58012163 A/G cg12615879 chr12:58013172 SLC26A10 -0.33 -6.51 -0.33 2.6200000000000003e-10 Multiple sclerosis; LIHC cis rs9467773 0.869 rs9295689 chr6:26455811 T/C cg09904177 chr6:26538194 HMGN4 0.46 8.4 0.41 1.22e-15 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.691 rs17009144 chr4:120270795 C/T cg09307838 chr4:120376055 NA -0.62 -9.89 -0.47 1.88e-20 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11079354 chr6:27740361 NA 0.46 7.05 0.36 9.7e-12 Pancreatic cancer; LIHC cis rs2257205 0.588 rs7219856 chr17:56941020 C/T cg05425664 chr17:57184151 TRIM37 -0.61 -6.69 -0.34 9.14e-11 Pancreatic cancer; LIHC cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.67 0.57 1.98e-30 Total body bone mineral density; LIHC cis rs4663866 0.901 rs76312449 chr2:239190906 A/G cg16914508 chr2:239161102 PER2 0.83 5.97 0.31 5.94e-9 Irritable bowel syndrome; LIHC cis rs17102884 0.506 rs10873274 chr14:75407372 G/T cg11812906 chr14:75593930 NEK9 -0.48 -8.06 -0.4 1.3e-14 Neuroticism; LIHC cis rs11105298 0.891 rs11105310 chr12:89918677 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.33 -0.37 1.63e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs589448 0.902 rs315138 chr12:69764850 A/T cg22834771 chr12:69754056 YEATS4 -0.55 -9.98 -0.47 9.62e-21 Cerebrospinal fluid biomarker levels; LIHC cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg15320075 chr8:145703422 NA -0.55 -9.46 -0.46 5.3e-19 Age at first birth; LIHC cis rs72627123 0.867 rs73303129 chr14:74489244 A/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.92 9.76 0.47 5.28e-20 Morning vs. evening chronotype; LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg19318889 chr4:1322082 MAEA 0.64 10.07 0.48 4.57e-21 Longevity; LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.61 0.8 1.06e-77 Prudent dietary pattern; LIHC cis rs12497850 0.866 rs6791234 chr3:48996137 A/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.15 0.36 5.31e-12 Parkinson's disease; LIHC trans rs6598955 0.617 rs11247883 chr1:26576247 T/G cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC cis rs61990749 0.597 rs717683 chr14:78255453 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.63 -0.38 2.36e-13 Fibroblast growth factor basic levels; LIHC cis rs992157 0.560 rs6436048 chr2:219109033 C/T cg00012203 chr2:219082015 ARPC2 0.89 15.59 0.64 9.3e-42 Colorectal cancer; LIHC cis rs1975974 1.000 rs4889703 chr17:21721663 T/C cg18423549 chr17:21743878 NA -0.46 -6.13 -0.31 2.47e-9 Psoriasis; LIHC cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg26939375 chr7:64535504 NA 0.47 7.95 0.39 2.81e-14 Calcium levels; LIHC cis rs986417 1.000 rs12587609 chr14:60928850 C/G cg27398547 chr14:60952738 C14orf39 0.81 9.56 0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs68170813 0.599 rs6466162 chr7:106902625 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.91 -0.3 8.3e-9 Coronary artery disease; LIHC cis rs8114671 0.804 rs3803936 chr20:33632775 T/C cg07148914 chr20:33460835 GGT7 -0.55 -8.43 -0.41 9.93e-16 Height; LIHC cis rs6867032 0.958 rs9312970 chr5:2002415 C/A cg26168224 chr5:2018326 NA -0.28 -7.01 -0.35 1.27e-11 Gut microbiome composition (winter); LIHC cis rs7106204 1.000 rs35876423 chr11:24214859 G/T ch.11.24196551F chr11:24239977 NA 0.68 6.83 0.35 3.89e-11 Response to Homoharringtonine (cytotoxicity); LIHC cis rs13191362 1.000 rs35754151 chr6:163074867 A/G cg14584255 chr6:163149320 PACRG;PARK2 0.65 5.84 0.3 1.21e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7618501 1.000 rs11130218 chr3:49752372 C/T cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs11734570 0.581 rs76682731 chr4:38586045 T/C cg18361445 chr4:38666374 KLF3;FLJ13197 0.47 6.27 0.32 1.1e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7412746 0.658 rs10888397 chr1:150886752 A/G cg15448220 chr1:150897856 SETDB1 -0.37 -6.07 -0.31 3.38e-9 Melanoma; LIHC cis rs9326248 1.000 rs585849 chr11:117069061 A/G cg11861562 chr11:117069780 TAGLN 0.49 8.01 0.4 1.82e-14 Blood protein levels; LIHC cis rs875971 0.862 rs10240949 chr7:65804417 A/G cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.07e-40 Aortic root size; LIHC cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg00149659 chr3:10157352 C3orf10 0.75 7.61 0.38 2.61e-13 Alzheimer's disease; LIHC cis rs5769765 1.000 rs5769760 chr22:50259696 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs68170813 0.559 rs78888729 chr7:106940957 G/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg12297030 chr17:43662878 NA -0.63 -6.06 -0.31 3.69e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2228479 0.702 rs11076621 chr16:89837927 A/G cg06558623 chr16:89946397 TCF25 0.89 12.39 0.56 2.18e-29 Skin colour saturation; LIHC trans rs2284367 0.505 rs4756151 chr11:34495358 C/A cg02390588 chr12:53722253 SP7 -0.4 -6.06 -0.31 3.55e-9 Blood protein levels; LIHC cis rs7772486 0.875 rs932522 chr6:146374026 A/G cg23711669 chr6:146136114 FBXO30 -0.68 -12.27 -0.55 6.1e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg10755058 chr3:40428713 ENTPD3 0.36 6.06 0.31 3.67e-9 Renal cell carcinoma; LIHC cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg02290350 chr8:58132656 NA 0.38 8.15 0.4 6.86e-15 Developmental language disorder (linguistic errors); LIHC cis rs12887734 0.546 rs4906376 chr14:104272165 A/C cg08213375 chr14:104286397 PPP1R13B 0.56 9.76 0.47 5.21e-20 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.67 8.04 0.4 1.52e-14 Mean platelet volume; LIHC trans rs116095464 0.558 rs62346526 chr5:220614 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs9399135 0.935 rs11760000 chr6:135370496 G/A cg22676075 chr6:135203613 NA 0.41 6.5 0.33 2.93e-10 Red blood cell count; LIHC cis rs1707322 0.964 rs785516 chr1:46564758 T/G cg03146154 chr1:46216737 IPP -0.45 -7.25 -0.36 2.82e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6598955 0.640 rs1577507 chr1:26547179 C/T cg04990556 chr1:26633338 UBXN11 -0.55 -9.05 -0.44 1.12e-17 Obesity-related traits; LIHC cis rs2522056 1.000 rs2706379 chr5:131805735 C/T cg24060327 chr5:131705240 SLC22A5 0.55 7.44 0.37 8.01e-13 Lymphocyte counts;Fibrinogen; LIHC cis rs1577917 0.958 rs11758508 chr6:86506878 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.53 9.39 0.45 8.53e-19 Response to antipsychotic treatment; LIHC cis rs4908768 0.501 rs1473420 chr1:8616838 T/G cg20416874 chr1:8611966 RERE -0.7 -15.26 -0.64 1.9e-40 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2354432 0.882 rs11576360 chr1:146740576 G/A cg25205988 chr1:146714368 CHD1L 1.06 19.53 0.73 1.43e-57 Mitochondrial DNA levels; LIHC cis rs6761276 0.505 rs13019891 chr2:113829869 G/T cg12858261 chr2:113808755 IL1F8 0.42 6.64 0.34 1.21e-10 Protein quantitative trait loci; LIHC cis rs240764 0.658 rs2132168 chr6:101178491 G/A cg09795085 chr6:101329169 ASCC3 -0.44 -6.48 -0.33 3.16e-10 Neuroticism; LIHC cis rs1005277 0.579 rs2472181 chr10:38386764 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs12926788 0.640 rs73551577 chr16:24845143 G/A cg00339695 chr16:24857497 SLC5A11 0.7 10.44 0.49 2.52e-22 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs6545883 0.525 rs1177274 chr2:61368532 T/G cg15711740 chr2:61764176 XPO1 -0.41 -5.91 -0.3 8.17e-9 Tuberculosis; LIHC cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.66e-9 Bipolar disorder; LIHC cis rs760805 1.000 rs4648884 chr1:25261386 C/T cg22509179 chr1:25234806 RUNX3 0.38 8.06 0.4 1.27e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs875971 0.964 rs778735 chr7:65814809 C/A cg18252515 chr7:66147081 NA -0.42 -5.87 -0.3 1.01e-8 Aortic root size; LIHC cis rs372883 0.648 rs2832296 chr21:30741454 C/T cg24692254 chr21:30365293 RNF160 -0.5 -6.41 -0.33 4.76e-10 Pancreatic cancer; LIHC cis rs3791556 1.000 rs3791556 chr2:240112972 G/A cg03281426 chr2:240109471 HDAC4 0.41 6.17 0.32 1.88e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7412746 0.658 rs17660092 chr1:150797748 T/C cg18016565 chr1:150552671 MCL1 0.54 10.25 0.48 1.12e-21 Melanoma; LIHC cis rs68170813 0.559 rs4730226 chr7:106887274 A/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs12701220 0.522 rs868833 chr7:1054973 C/G cg16145915 chr7:1198662 ZFAND2A -0.27 -5.87 -0.3 1.04e-8 Bronchopulmonary dysplasia; LIHC cis rs11018874 0.597 rs4268468 chr11:89886284 C/T cg05041596 chr11:89867385 NAALAD2 0.44 7.45 0.37 7.46e-13 White blood cell types; LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg08219700 chr8:58056026 NA 0.53 7.18 0.36 4.45e-12 Developmental language disorder (linguistic errors); LIHC cis rs72772090 1.000 rs72772090 chr5:96036311 G/C cg17330273 chr5:96107758 CAST;ERAP1 -0.57 -6.47 -0.33 3.46e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10751667 0.643 rs11246344 chr11:933783 A/C cg10932868 chr11:921992 NA 0.38 7.32 0.37 1.83e-12 Alzheimer's disease (late onset); LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg00656387 chr3:40428638 ENTPD3 0.5 8.37 0.41 1.44e-15 Renal cell carcinoma; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.75 0.8 3.17e-78 Prudent dietary pattern; LIHC cis rs2976388 0.609 rs2164308 chr8:143785659 A/G cg06565975 chr8:143823917 SLURP1 -0.33 -6.44 -0.33 4.16e-10 Urinary tract infection frequency; LIHC cis rs7131987 0.903 rs11050152 chr12:29404424 G/T cg21486233 chr12:29375141 FAR2 0.3 5.8 0.3 1.48e-8 QT interval; LIHC cis rs11958404 0.932 rs72816595 chr5:157435957 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs11190604 1.000 rs1106565 chr10:102211613 T/C cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs910316 0.967 rs8007539 chr14:75664953 T/C cg11812906 chr14:75593930 NEK9 -0.68 -12.68 -0.57 1.85e-30 Height; LIHC trans rs116095464 0.614 rs62344339 chr5:252995 T/G cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs7100689 0.646 rs10788586 chr10:82117435 A/G cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs17106184 1.000 rs56298082 chr1:50949727 C/T cg07174182 chr1:51127561 FAF1 -0.58 -6.59 -0.34 1.64e-10 Type 2 diabetes; LIHC cis rs6502050 0.835 rs8070014 chr17:80115247 T/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.68e-9 Life satisfaction; LIHC cis rs11112613 0.609 rs6539218 chr12:105934875 C/T cg03607813 chr12:105948248 NA 0.56 9.82 0.47 3.32e-20 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7927592 0.956 rs10896334 chr11:68281494 C/T cg01657329 chr11:68192670 LRP5 -0.47 -6.09 -0.31 3.12e-9 Total body bone mineral density; LIHC trans rs61931739 0.534 rs12371021 chr12:34062252 T/C cg26384229 chr12:38710491 ALG10B 0.49 6.83 0.35 3.81e-11 Morning vs. evening chronotype; LIHC cis rs9549367 0.789 rs7999579 chr13:113879357 T/C cg18105134 chr13:113819100 PROZ -0.67 -11.55 -0.53 2.82e-26 Platelet distribution width; LIHC cis rs600806 0.854 rs11142 chr1:109897103 A/G cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.09 -0.36 7.73e-12 Intelligence (multi-trait analysis); LIHC cis rs5758511 0.689 rs55906806 chr22:42644471 C/T cg00645731 chr22:42541494 CYP2D7P1 0.66 6.15 0.32 2.2e-9 Birth weight; LIHC cis rs727563 0.593 rs132770 chr22:42017264 A/G cg06481639 chr22:41940642 POLR3H 0.6 5.8 0.3 1.48e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7072216 0.691 rs3829853 chr10:100171174 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs611744 0.870 rs596703 chr8:109160146 A/G cg18478394 chr8:109455254 TTC35 -0.41 -6.87 -0.35 3.01e-11 Dupuytren's disease; LIHC cis rs4820294 1.000 rs78974622 chr22:38059925 A/C cg10587741 chr22:38071170 LGALS1 0.72 12.65 0.56 2.46e-30 Fat distribution (HIV); LIHC cis rs9300255 0.568 rs1790108 chr12:123636841 A/G cg00376283 chr12:123451042 ABCB9 0.65 7.4 0.37 1.08e-12 Neutrophil percentage of white cells; LIHC cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg27297192 chr10:134578999 INPP5A 0.53 7.42 0.37 9.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs965469 1.000 rs6051732 chr20:3294182 G/A cg25506879 chr20:3388711 C20orf194 -0.6 -6.91 -0.35 2.43e-11 IFN-related cytopenia; LIHC trans rs116095464 0.558 rs28418643 chr5:240859 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.11 0.36 7.03e-12 Breast cancer; LIHC cis rs6912958 0.703 rs6903219 chr6:88096498 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.4 7.94 0.39 2.96e-14 Monocyte percentage of white cells; LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg07308232 chr7:1071921 C7orf50 -0.4 -6.48 -0.33 3.18e-10 Longevity;Endometriosis; LIHC cis rs7769051 1.000 rs9493454 chr6:133144629 G/T cg22852734 chr6:133119734 C6orf192 -0.89 -9.69 -0.46 8.77e-20 Type 2 diabetes nephropathy; LIHC cis rs7131987 0.845 rs7299861 chr12:29409667 G/A cg00204748 chr12:29376779 FAR2 0.44 8.32 0.41 2.08e-15 QT interval; LIHC cis rs72781680 0.611 rs56113233 chr2:24341085 A/C cg06627628 chr2:24431161 ITSN2 -0.62 -7.31 -0.37 1.88e-12 Lymphocyte counts; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg12419862 chr22:24373484 LOC391322 -0.65 -9.68 -0.46 9.66e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2070488 0.965 rs7372386 chr3:38484175 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.94 16.08 0.66 1.01e-43 Electrocardiographic conduction measures; LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg09455208 chr3:40491958 NA 0.4 8.3 0.41 2.47e-15 Renal cell carcinoma; LIHC cis rs5753618 0.539 rs2106294 chr22:31645759 C/T cg22777020 chr22:31556080 RNF185 -0.56 -6.48 -0.33 3.19e-10 Colorectal cancer; LIHC cis rs4808199 0.948 rs2301671 chr19:19466269 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.57 8.24 0.41 3.74e-15 Nonalcoholic fatty liver disease; LIHC cis rs9660992 0.710 rs4951184 chr1:205240659 A/T cg21545522 chr1:205238299 TMCC2 0.37 7.16 0.36 4.91e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2304069 0.526 rs6863283 chr5:149402448 C/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.6 8.46 0.42 7.83e-16 HIV-1 control; LIHC cis rs8048589 0.526 rs71388721 chr16:12212164 G/A cg02910054 chr16:12241554 SNX29 0.28 6.83 0.35 3.92e-11 Homeostasis model assessment of insulin resistance (dietary factor interaction);Fasting insulin (dietary factor interaction); LIHC cis rs17125944 0.505 rs17125746 chr14:53236079 C/T cg00686598 chr14:53173677 PSMC6 1.2 14.61 0.62 6.57e-38 Alzheimer's disease (late onset); LIHC cis rs7582180 0.638 rs6734316 chr2:100976210 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.17 0.4 5.93e-15 Intelligence (multi-trait analysis); LIHC cis rs7618501 0.521 rs3774759 chr3:49939120 G/T cg24110177 chr3:50126178 RBM5 -0.55 -8.66 -0.42 1.95e-16 Intelligence (multi-trait analysis); LIHC cis rs1419980 0.673 rs2377086 chr12:7753798 C/T cg25828445 chr12:7781288 NA 0.45 6.93 0.35 2.09e-11 HDL cholesterol levels; LIHC cis rs2991971 0.747 rs2492841 chr1:45894891 G/T cg15605315 chr1:45957053 TESK2 -0.49 -6.92 -0.35 2.27e-11 High light scatter reticulocyte count; LIHC cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg06481639 chr22:41940642 POLR3H -0.74 -7.53 -0.38 4.6e-13 Vitiligo; LIHC cis rs748404 0.723 rs560134 chr15:43555699 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.47 8.02 0.4 1.71e-14 Lung cancer; LIHC cis rs17826219 0.706 rs73271850 chr17:29142140 A/G cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Body mass index; LIHC cis rs9393692 0.875 rs6939589 chr6:26289203 C/T cg00631329 chr6:26305371 NA 0.43 7.31 0.37 1.92e-12 Educational attainment; LIHC cis rs1878931 0.624 rs1149492 chr16:3445239 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.69 -8.96 -0.44 2.07e-17 Body mass index (adult); LIHC cis rs926392 0.896 rs1569538 chr20:37685216 A/G cg16355469 chr20:37678765 NA -0.39 -6.38 -0.33 5.65e-10 Dialysis-related mortality; LIHC cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg11644478 chr21:40555479 PSMG1 -0.38 -5.88 -0.3 1e-8 Cognitive function; LIHC cis rs12477438 0.561 rs2084988 chr2:99655755 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs9467773 1.000 rs4871 chr6:26545632 G/A cg11502198 chr6:26597334 ABT1 0.4 5.84 0.3 1.24e-8 Intelligence (multi-trait analysis); LIHC cis rs858239 0.676 rs274032 chr7:23374559 C/G cg00469287 chr7:23338798 C7orf30 0.49 6.61 0.34 1.46e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs9790314 0.905 rs4518145 chr3:160950030 T/C cg03342759 chr3:160939853 NMD3 -0.74 -9.6 -0.46 1.83e-19 Morning vs. evening chronotype; LIHC cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg05590025 chr7:65112418 INTS4L2 0.67 7.36 0.37 1.34e-12 Diabetic kidney disease; LIHC cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg02290350 chr8:58132656 NA 0.37 8.5 0.42 5.81e-16 Developmental language disorder (linguistic errors); LIHC cis rs2559856 1.000 rs2559855 chr12:102090080 A/G cg12924262 chr12:102091054 CHPT1 -0.49 -7.75 -0.39 1.08e-13 Blood protein levels; LIHC cis rs8060686 0.623 rs7204208 chr16:68069416 A/G cg05110241 chr16:68378359 PRMT7 -0.53 -6.3 -0.32 9.22e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs9902453 0.933 rs9898353 chr17:28451865 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.61 9.46 0.46 5.05e-19 Coffee consumption (cups per day); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg11313997 chr5:177027589 B4GALT7 0.41 6.43 0.33 4.18e-10 Morning vs. evening chronotype; LIHC cis rs7833986 0.501 rs72653959 chr8:56996516 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.06e-16 Height; LIHC cis rs3806843 0.735 rs813897 chr5:140070029 T/C cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs79149102 0.579 rs61166993 chr15:75306644 C/A cg16226627 chr15:75307476 SCAMP5 0.52 9.74 0.47 6.22e-20 Lung cancer; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg26338869 chr17:61819248 STRADA 0.58 8.45 0.42 8.29e-16 Prudent dietary pattern; LIHC cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg03264133 chr6:25882463 NA 0.51 6.33 0.32 7.82e-10 Intelligence (multi-trait analysis); LIHC cis rs2084898 0.550 rs470411 chr11:120012390 G/C cg16945685 chr11:120038821 NA -0.38 -6.58 -0.34 1.75e-10 Stroke (pediatric); LIHC cis rs7914558 1.000 rs12255047 chr10:104760752 G/A cg04362960 chr10:104952993 NT5C2 0.38 5.76 0.3 1.92e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs11122272 0.735 rs2749704 chr1:231526243 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg06108461 chr20:60628389 TAF4 1.01 16.52 0.67 1.68e-45 Body mass index; LIHC trans rs8117834 0.574 rs73076256 chr20:8089458 A/C cg00593689 chr4:53575888 NA 0.38 6.38 0.33 5.83e-10 Chronic kidney disease; LIHC cis rs10838687 0.932 rs4752973 chr11:47269159 T/C cg26139080 chr11:47293733 MADD -0.44 -6.49 -0.33 3.06e-10 Proinsulin levels; LIHC cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg05368731 chr17:41323189 NBR1 0.73 12.42 0.56 1.7e-29 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05968270 chr1:65533502 NA 0.46 6.2 0.32 1.67e-9 Lung function (FEV1/FVC); LIHC cis rs4555082 1.000 rs4334224 chr14:105759198 C/T cg13114125 chr14:105738426 BRF1 -0.7 -9.36 -0.45 1.08e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs4746818 0.711 rs2491024 chr10:70847084 T/C cg11621586 chr10:70884670 VPS26A 0.52 8.02 0.4 1.67e-14 Left atrial antero-posterior diameter; LIHC trans rs950169 0.545 rs4354897 chr15:84644971 T/C cg00571809 chr1:3397113 ARHGEF16 0.38 6.29 0.32 9.5e-10 Schizophrenia; LIHC cis rs6466055 0.777 rs2240463 chr7:104844328 C/T cg04380332 chr7:105027541 SRPK2 -0.36 -6.85 -0.35 3.46e-11 Schizophrenia; LIHC cis rs11628318 0.572 rs7142319 chr14:103119425 C/T cg12046867 chr14:103022105 NA 0.38 5.87 0.3 1.03e-8 Platelet count; LIHC cis rs13392177 0.660 rs10932762 chr2:219076213 G/C cg20019365 chr2:219134978 PNKD;AAMP -0.55 -7.82 -0.39 6.54e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC trans rs208520 0.690 rs12208310 chr6:66730108 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 9.02 0.44 1.34e-17 Exhaled nitric oxide output; LIHC cis rs2439831 0.850 rs28413881 chr15:44174099 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 7.62 0.38 2.46e-13 Lung cancer in ever smokers; LIHC cis rs3790645 1.000 rs383913 chr1:26893306 A/G cg17456097 chr1:26900765 RPS6KA1 0.41 5.88 0.3 9.94e-9 Glucose homeostasis traits; LIHC cis rs732505 1.000 rs4807789 chr19:5584448 T/C cg26242866 chr19:5711310 LONP1 0.88 6.48 0.33 3.28e-10 vWF and FVIII levels; LIHC cis rs67478160 0.643 rs3818085 chr14:104215985 C/T cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.57 -0.38 3.54e-13 Schizophrenia; LIHC cis rs6500602 0.739 rs4786502 chr16:4537104 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.49 7.64 0.38 2.28e-13 Schizophrenia; LIHC cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg24549020 chr5:56110836 MAP3K1 0.48 6.28 0.32 1.03e-9 Initial pursuit acceleration; LIHC cis rs2404602 0.684 rs4886819 chr15:76901698 C/T cg03037974 chr15:76606532 NA -0.61 -10.2 -0.48 1.73e-21 Blood metabolite levels; LIHC cis rs3096299 0.900 rs744327 chr16:89439270 C/T cg02187348 chr16:89574699 SPG7 0.45 6.43 0.33 4.22e-10 Multiple myeloma (IgH translocation); LIHC cis rs2932538 0.922 rs12143068 chr1:113138110 A/G cg22162597 chr1:113214053 CAPZA1 0.72 11.08 0.51 1.43e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs912057 0.965 rs1294409 chr6:6738355 A/G cg06612196 chr6:6737390 NA -0.54 -10.04 -0.48 5.83e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg08677398 chr8:58056175 NA 0.39 5.75 0.3 1.95e-8 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg21724239 chr8:58056113 NA 0.49 6.43 0.33 4.17e-10 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.956 rs7316149 chr12:123063912 G/A cg23029597 chr12:123009494 RSRC2 -0.52 -7.38 -0.37 1.22e-12 Body mass index; LIHC cis rs5769765 0.778 rs4574208 chr22:50256738 C/T cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs589448 0.902 rs315131 chr12:69761839 T/G cg20891283 chr12:69753455 YEATS4 0.95 22.45 0.77 3.15e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs6933660 0.760 rs6904364 chr6:151754273 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.58 9.51 0.46 3.51e-19 Menarche (age at onset); LIHC cis rs11822910 0.737 rs2729389 chr11:57211646 A/G cg00522883 chr11:57194120 SLC43A3 -0.55 -7.67 -0.38 1.81e-13 Platelet distribution width; LIHC cis rs9457247 1.000 rs4710147 chr6:167374239 G/A cg12798992 chr6:167411361 FGFR1OP -0.6 -9.93 -0.47 1.41e-20 Crohn's disease; LIHC cis rs907683 0.584 rs12920 chr2:220285666 C/G cg15015639 chr2:220282977 DES 0.37 9.02 0.44 1.35e-17 Resting heart rate; LIHC cis rs600806 0.778 rs2140923 chr1:110004990 C/T cg23091122 chr1:110024289 SYPL2 -0.51 -6.81 -0.35 4.42e-11 Intelligence (multi-trait analysis); LIHC cis rs12980942 0.810 rs16958999 chr19:41825186 A/G cg25627403 chr19:41769009 HNRNPUL1 0.47 5.91 0.3 8.07e-9 Coronary artery disease; LIHC cis rs6847149 1.000 rs6852679 chr4:110804414 T/C cg07850274 chr4:110748770 RRH 0.43 6.02 0.31 4.59e-9 Exercise treadmill test traits; LIHC cis rs597539 0.652 rs686390 chr11:68656077 T/C cg04772025 chr11:68637568 NA 0.46 5.94 0.31 6.97e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs644799 1.000 rs514170 chr11:95556696 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs61677309 1.000 rs3825051 chr11:118174629 A/G cg06090739 chr11:118230722 UBE4A 0.35 6.44 0.33 4.11e-10 Lung cancer in ever smokers; LIHC cis rs1552244 0.572 rs3843008 chr3:10173742 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 8.67 0.42 1.82e-16 Alzheimer's disease; LIHC trans rs875971 0.619 rs2302918 chr7:66000932 A/G cg26939375 chr7:64535504 NA 0.43 7.0 0.35 1.36e-11 Aortic root size; LIHC cis rs68170813 0.559 rs75203426 chr7:107017589 G/C cg02696742 chr7:106810147 HBP1 -0.5 -5.83 -0.3 1.29e-8 Coronary artery disease; LIHC cis rs918629 0.716 rs12055262 chr5:95274632 T/C cg10483112 chr5:95245456 ELL2 -0.35 -6.02 -0.31 4.47e-9 IgG glycosylation; LIHC cis rs4575098 0.681 rs11589567 chr1:161116022 G/T cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.43 7.72 0.39 1.29e-13 Monocyte percentage of white cells; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg03721293 chr16:90014378 DEF8 0.37 6.2 0.32 1.64e-9 Skin colour saturation; LIHC cis rs2204008 0.805 rs12146846 chr12:37985847 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs1790761 0.692 rs674783 chr11:67339076 C/T cg21734168 chr11:67353974 GSTP1 -0.28 -6.79 -0.34 4.99e-11 Mean corpuscular volume; LIHC cis rs9790314 0.560 rs1450521 chr3:161091237 C/A cg17135325 chr3:160939158 NMD3 0.42 6.09 0.31 3.06e-9 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg20607798 chr8:58055168 NA 0.69 8.23 0.41 3.93e-15 Developmental language disorder (linguistic errors); LIHC cis rs422249 0.720 rs174455 chr11:61656117 A/G cg27386326 chr11:61587980 NA 0.34 6.15 0.32 2.21e-9 Trans fatty acid levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10920230 chr7:150757210 SLC4A2 -0.43 -6.28 -0.32 1.02e-9 Calcium levels; LIHC trans rs4906332 0.840 rs34161327 chr14:103857325 G/A cg17675199 chr6:35436792 RPL10A 0.32 6.33 0.32 7.48e-10 Coronary artery disease; LIHC cis rs1401999 0.690 rs1402001 chr3:183642751 A/G cg01324343 chr3:183735012 ABCC5 0.52 8.44 0.42 8.87e-16 Anterior chamber depth; LIHC cis rs4650994 0.593 rs6700266 chr1:178508930 A/G cg05350800 chr1:178550844 NA 0.3 6.39 0.33 5.51e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9649465 0.967 rs13230230 chr7:123329603 G/A cg03229431 chr7:123269106 ASB15 -0.38 -8.18 -0.4 5.61e-15 Migraine; LIHC cis rs7659604 0.560 rs769238 chr4:122744942 G/A cg20573242 chr4:122745356 CCNA2 0.52 7.63 0.38 2.37e-13 Type 2 diabetes; LIHC cis rs9902453 0.967 rs12449783 chr17:28527653 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.24 0.45 2.75e-18 Coffee consumption (cups per day); LIHC trans rs1814175 0.626 rs1722008 chr11:49897676 A/T cg15704280 chr7:45808275 SEPT13 -1.0 -22.37 -0.77 6.28e-69 Height; LIHC trans rs877282 0.797 rs7079164 chr10:756363 A/G cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs8067545 0.641 rs2108978 chr17:19861458 C/T cg13482628 chr17:19912719 NA 0.41 6.65 0.34 1.13e-10 Schizophrenia; LIHC cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg12463550 chr7:65579703 CRCP 0.67 7.03 0.36 1.15e-11 Diabetic kidney disease; LIHC trans rs7721647 0.778 rs1596055 chr5:90886601 A/T cg11567849 chr6:111751012 REV3L -0.5 -6.04 -0.31 3.95e-9 Breast cancer; LIHC cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg24531977 chr5:56204891 C5orf35 -0.68 -9.88 -0.47 2e-20 Initial pursuit acceleration; LIHC cis rs6424115 0.618 rs10917420 chr1:24062987 C/T cg10978503 chr1:24200527 CNR2 0.26 6.36 0.33 6.59e-10 Immature fraction of reticulocytes; LIHC trans rs7232775 0.818 rs1872357 chr18:43186262 A/G cg21675030 chr3:111697974 ABHD10 0.52 6.04 0.31 4.05e-9 Metabolite levels; LIHC cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg16434002 chr17:42200994 HDAC5 -0.55 -7.99 -0.4 2.11e-14 Total body bone mineral density; LIHC cis rs754466 0.830 rs61854186 chr10:79703255 G/A cg17075019 chr10:79541650 NA -0.57 -7.47 -0.37 6.63e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7188697 0.743 rs11859781 chr16:58602589 T/A cg02549819 chr16:58548995 SETD6 0.48 7.49 0.38 5.75e-13 QT interval; LIHC cis rs875971 0.862 rs6955837 chr7:66043142 C/T cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.22e-34 Aortic root size; LIHC cis rs9325144 0.560 rs11182979 chr12:38642562 C/A cg26384229 chr12:38710491 ALG10B -0.59 -8.08 -0.4 1.15e-14 Morning vs. evening chronotype; LIHC cis rs4665809 1.000 rs6729757 chr2:26285102 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.73 -8.95 -0.44 2.26e-17 Gut microbiome composition (summer); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23115136 chr7:100281759 GIGYF1 0.45 6.72 0.34 7.6e-11 Pancreatic cancer; LIHC trans rs7613875 0.641 rs2624845 chr3:50062437 C/A cg21659725 chr3:3221576 CRBN -0.55 -8.22 -0.41 4.22e-15 Body mass index; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg27262702 chr16:88878803 APRT -0.48 -6.34 -0.32 7.2e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs17608059 0.504 rs11656981 chr17:13978777 A/G cg11395062 chr17:14139857 CDRT15 0.63 11.88 0.54 1.81e-27 Temperament; LIHC cis rs17401966 0.838 rs1013952 chr1:10319247 G/A cg19773385 chr1:10388646 KIF1B -0.4 -7.35 -0.37 1.46e-12 Hepatocellular carcinoma; LIHC cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.27 -0.55 6.47e-29 Alzheimer's disease; LIHC cis rs9682041 0.825 rs6785326 chr3:170095145 T/C cg11886554 chr3:170076028 SKIL 0.75 6.33 0.32 7.84e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs253664 0.796 rs799328 chr3:138082705 T/G cg17918682 chr3:137893718 DBR1 -0.54 -5.72 -0.3 2.38e-8 Body mass index; LIHC cis rs921968 0.643 rs645796 chr2:219389236 A/G cg02985541 chr2:219472218 PLCD4 0.45 8.71 0.43 1.33e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs787274 0.543 rs1324930 chr9:115634639 A/G cg13803584 chr9:115635662 SNX30 0.58 8.49 0.42 6.21e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3806843 0.966 rs3756338 chr5:140180561 A/G cg19875535 chr5:140030758 IK 0.37 5.97 0.31 6.02e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9309473 0.950 rs6740766 chr2:73780913 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs2072499 0.966 rs1137703 chr1:156184458 T/C cg24450063 chr1:156163899 SLC25A44 1.07 19.01 0.72 1.71e-55 Testicular germ cell tumor; LIHC cis rs1003719 0.715 rs2252893 chr21:38507572 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.46e-25 Eye color traits; LIHC cis rs12368653 0.583 rs7952989 chr12:58095989 T/C cg12615879 chr12:58013172 SLC26A10 0.36 7.04 0.36 1.04e-11 Multiple sclerosis; LIHC cis rs11583043 0.874 rs72734253 chr1:101380718 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 9.22 0.45 3.06e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs12594515 1.000 rs7173144 chr15:45991196 A/G cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs9814567 1.000 rs6793487 chr3:134299426 C/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.93 0.31 7.23e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6502050 0.835 rs9911379 chr17:80114529 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.97 -0.31 6.06e-9 Life satisfaction; LIHC cis rs2050392 0.590 rs17547917 chr10:30718303 G/A cg25182066 chr10:30743637 MAP3K8 -0.62 -9.93 -0.47 1.44e-20 Inflammatory bowel disease; LIHC cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.06e-10 Alzheimer's disease; LIHC cis rs35146811 0.844 rs59261051 chr7:99650429 C/T cg13334819 chr7:99746414 C7orf59 -0.56 -7.83 -0.39 6.18e-14 Coronary artery disease; LIHC cis rs7224685 0.906 rs9915922 chr17:4083242 T/C cg09597638 chr17:3907349 NA 0.54 7.8 0.39 7.61e-14 Type 2 diabetes; LIHC cis rs2439831 0.867 rs8041132 chr15:43635136 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC cis rs4474465 0.646 rs6592794 chr11:78275743 A/G cg02023728 chr11:77925099 USP35 -0.34 -5.97 -0.31 5.95e-9 Alzheimer's disease (survival time); LIHC cis rs3818285 0.556 rs2084607 chr10:111681411 C/T cg00817464 chr10:111662876 XPNPEP1 0.54 8.95 0.44 2.32e-17 Superior crus of antihelix expression; LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg21248554 chr2:27665150 KRTCAP3 -0.44 -6.02 -0.31 4.43e-9 Total body bone mineral density; LIHC cis rs17384381 0.634 rs11801146 chr1:85915374 C/T cg16011679 chr1:85725395 C1orf52 0.82 8.97 0.44 1.97e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs1005277 0.579 rs2474580 chr10:38398713 G/A cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC trans rs1814175 0.616 rs28417656 chr11:50040152 C/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs13040088 0.580 rs11905041 chr20:61563408 C/T cg23096297 chr20:61557774 DIDO1 0.65 9.16 0.44 4.8e-18 Menopause (age at onset); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg00164150 chr2:20101139 TTC32 0.43 6.06 0.31 3.67e-9 Morning vs. evening chronotype; LIHC cis rs7927592 0.871 rs12360903 chr11:68236314 C/A cg16797656 chr11:68205561 LRP5 0.54 8.61 0.42 2.63e-16 Total body bone mineral density; LIHC cis rs11123170 0.640 rs1015754 chr2:113967990 T/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.53 -6.77 -0.34 5.7e-11 Renal function-related traits (BUN); LIHC cis rs11124272 0.868 rs477517 chr2:31848637 C/T cg02381751 chr2:32503542 YIPF4 0.42 5.77 0.3 1.75e-8 Interleukin-18 levels; LIHC cis rs8114671 0.836 rs6142280 chr20:33622242 A/C cg07148914 chr20:33460835 GGT7 -0.54 -8.28 -0.41 2.72e-15 Height; LIHC cis rs4975616 0.836 rs460073 chr5:1336459 T/C cg07493874 chr5:1342172 CLPTM1L -0.68 -11.03 -0.51 2.15e-24 Lung cancer; LIHC trans rs561341 1.000 rs473356 chr17:30321762 G/C cg20587970 chr11:113659929 NA -1.39 -11.8 -0.54 3.55e-27 Hip circumference adjusted for BMI; LIHC cis rs244293 1.000 rs244288 chr17:53231841 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.16 -0.36 4.99e-12 Menarche (age at onset); LIHC cis rs1005277 0.579 rs2023351 chr10:38378814 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs6570726 0.791 rs441290 chr6:145883183 A/G cg23711669 chr6:146136114 FBXO30 0.65 11.75 0.54 5.34e-27 Lobe attachment (rater-scored or self-reported); LIHC trans rs7178375 1.000 rs9806159 chr15:31209654 G/T cg04373760 chr16:53404718 NA 0.6 8.28 0.41 2.82e-15 Hypertriglyceridemia; LIHC cis rs17401966 0.838 rs4846212 chr1:10370312 T/C cg19773385 chr1:10388646 KIF1B -0.41 -7.46 -0.37 7.26e-13 Hepatocellular carcinoma; LIHC cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg05590025 chr7:65112418 INTS4L2 0.61 6.65 0.34 1.16e-10 Diabetic kidney disease; LIHC trans rs7613875 0.620 rs17657688 chr3:50033228 C/T cg21659725 chr3:3221576 CRBN -0.55 -8.17 -0.4 5.98e-15 Body mass index; LIHC cis rs9902453 0.967 rs1906451 chr17:28515479 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.16 0.44 4.86e-18 Coffee consumption (cups per day); LIHC cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.45 0.56 1.3e-29 Alzheimer's disease; LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg09455208 chr3:40491958 NA -0.36 -7.38 -0.37 1.22e-12 Renal cell carcinoma; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.36 0.45 1.08e-18 Height; LIHC cis rs17102423 0.594 rs1270074 chr14:65564856 T/C cg16583315 chr14:65563665 MAX -0.38 -7.85 -0.39 5.55e-14 Obesity-related traits; LIHC cis rs10845606 1.000 rs11055013 chr12:12829037 T/C cg09462578 chr12:12878428 APOLD1 -0.76 -10.67 -0.5 3.99e-23 Systemic lupus erythematosus; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14817848 chr12:12715558 DUSP16 -0.48 -6.42 -0.33 4.53e-10 Systolic blood pressure; LIHC cis rs10861342 1.000 rs2888841 chr12:105493750 C/T cg23923672 chr12:105501055 KIAA1033 0.65 7.59 0.38 2.99e-13 IgG glycosylation; LIHC cis rs7296418 0.636 rs11057261 chr12:123797567 T/C cg05973401 chr12:123451056 ABCB9 0.41 6.33 0.32 7.53e-10 Platelet count; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg07677032 chr17:61819896 STRADA 0.44 6.44 0.33 4.01e-10 Prudent dietary pattern; LIHC cis rs8060686 0.516 rs2290700 chr16:68288983 T/G cg05110241 chr16:68378359 PRMT7 -0.54 -6.51 -0.33 2.67e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs3106136 0.967 rs13132963 chr4:95219780 A/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.93 -0.39 3.04e-14 Capecitabine sensitivity; LIHC cis rs11628318 0.515 rs60573537 chr14:103150407 A/G cg12046867 chr14:103022105 NA 0.39 5.95 0.31 6.78e-9 Platelet count; LIHC cis rs7208859 0.623 rs216436 chr17:28922900 G/A cg13385521 chr17:29058706 SUZ12P 0.69 6.6 0.34 1.55e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs611744 0.870 rs613179 chr8:109166006 G/A cg21045802 chr8:109455806 TTC35 0.57 9.86 0.47 2.31e-20 Dupuytren's disease; LIHC cis rs2439831 0.867 rs2251844 chr15:43836478 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 7.26 0.37 2.71e-12 Lung cancer in ever smokers; LIHC cis rs9549367 0.789 rs9549708 chr13:113891887 A/G cg00898013 chr13:113819073 PROZ -0.43 -7.43 -0.37 9.04e-13 Platelet distribution width; LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg16070018 chr6:26224392 HIST1H3E 0.59 7.45 0.37 7.55e-13 Gout;Renal underexcretion gout; LIHC cis rs965469 1.000 rs2236098 chr20:3267133 A/G cg25506879 chr20:3388711 C20orf194 -0.58 -7.06 -0.36 9.15e-12 IFN-related cytopenia; LIHC trans rs1814175 0.669 rs10839315 chr11:49654406 G/A cg15704280 chr7:45808275 SEPT13 -0.65 -11.21 -0.52 4.6e-25 Height; LIHC cis rs2380220 0.574 rs7766765 chr6:95997362 G/A cg15832292 chr6:96025679 MANEA 0.61 8.01 0.4 1.76e-14 Behavioural disinhibition (generation interaction); LIHC cis rs7647973 1.000 rs62259944 chr3:49430883 G/A cg07636037 chr3:49044803 WDR6 -0.52 -6.11 -0.31 2.65e-9 Menarche (age at onset); LIHC cis rs8072100 0.745 rs7214410 chr17:45422628 A/G cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.76 -0.3 1.83e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs818427 1.000 rs514763 chr5:112215156 C/T cg07820702 chr5:112228657 REEP5 -0.36 -5.77 -0.3 1.79e-8 Total body bone mineral density; LIHC cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.39 0.37 1.15e-12 Obesity-related traits; LIHC cis rs9640161 0.636 rs56190213 chr7:150025720 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.53 -8.82 -0.43 6.16e-17 Blood protein levels;Circulating chemerin levels; LIHC trans rs7178375 1.000 rs7176351 chr15:31208727 G/A cg04373760 chr16:53404718 NA 0.62 8.19 0.4 5.18e-15 Hypertriglyceridemia; LIHC cis rs2455799 0.613 rs11128760 chr3:15873407 A/G cg12698662 chr3:15914712 MIR563 -0.39 -7.23 -0.36 3.24e-12 Mean platelet volume; LIHC cis rs7107174 1.000 rs2510045 chr11:77920563 G/T cg02023728 chr11:77925099 USP35 0.47 8.66 0.42 1.93e-16 Testicular germ cell tumor; LIHC cis rs743757 1.000 rs2236965 chr3:50453456 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.62 0.38 2.47e-13 Diastolic blood pressure; LIHC cis rs798554 0.757 rs1182185 chr7:2872233 A/G cg04166393 chr7:2884313 GNA12 0.46 6.1 0.31 2.92e-9 Height; LIHC cis rs4824093 0.610 rs4824113 chr22:50284974 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.73 -5.76 -0.3 1.83e-8 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs918629 0.679 rs56002885 chr5:95269602 A/G cg10483112 chr5:95245456 ELL2 -0.37 -6.28 -0.32 1.02e-9 IgG glycosylation; LIHC cis rs7615952 0.673 rs9289270 chr3:125636979 A/T cg05084668 chr3:125655381 ALG1L -0.81 -10.57 -0.5 8.43e-23 Blood pressure (smoking interaction); LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.18 0.36 4.33e-12 Cognitive function; LIHC cis rs7512552 0.803 rs3738487 chr1:150477061 C/T cg15654264 chr1:150340011 RPRD2 0.71 11.53 0.53 3.24e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs7953249 0.618 rs7954039 chr12:121398654 A/C cg02403541 chr12:121454288 C12orf43 -0.42 -7.39 -0.37 1.12e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs1670533 1.000 rs633556 chr4:1092405 A/G cg27284194 chr4:1044797 NA 0.58 8.66 0.42 1.85e-16 Recombination rate (females); LIHC cis rs10792665 0.575 rs7113058 chr11:82559902 C/T cg24227371 chr11:82718527 RAB30 -0.26 -6.25 -0.32 1.19e-9 Obesity-related traits; LIHC cis rs4803468 1.000 rs284657 chr19:41929915 G/C cg14132834 chr19:41945861 ATP5SL -0.45 -6.54 -0.33 2.2e-10 Height; LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs11168351 1.000 rs11168351 chr12:48403765 C/T cg21466736 chr12:48725269 NA -0.4 -5.93 -0.31 7.35e-9 Bipolar disorder and schizophrenia; LIHC cis rs7903847 0.642 rs10786341 chr10:99158607 G/A cg06359132 chr10:99160096 RRP12 -0.42 -6.51 -0.33 2.73e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg07677032 chr17:61819896 STRADA 0.43 6.25 0.32 1.23e-9 Prudent dietary pattern; LIHC cis rs763121 0.719 rs138699 chr22:39129708 G/A cg06022373 chr22:39101656 GTPBP1 0.69 12.39 0.56 2.24e-29 Menopause (age at onset); LIHC cis rs7572733 0.555 rs6729473 chr2:198763928 G/A cg10820045 chr2:198174542 NA 0.48 7.27 0.37 2.45e-12 Dermatomyositis; LIHC cis rs5769765 0.862 rs9616774 chr22:50290599 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.15 -0.44 5.07e-18 Schizophrenia; LIHC cis rs4700695 0.719 rs27587 chr5:65444163 C/T cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.49e-15 Facial morphology (factor 19); LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg15362194 chr2:98262546 COX5B 0.51 6.14 0.32 2.31e-9 Glycated hemoglobin levels; LIHC cis rs6933660 0.745 rs6557138 chr6:151732017 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.54 8.05 0.4 1.38e-14 Menarche (age at onset); LIHC cis rs921968 0.643 rs523396 chr2:219338789 T/G cg02985541 chr2:219472218 PLCD4 0.45 8.74 0.43 1.06e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs7503168 1.000 rs10512472 chr17:33884804 A/G cg20932281 chr17:33905541 PEX12 0.57 7.49 0.38 5.74e-13 Plateletcrit; LIHC cis rs7903847 0.642 rs11189204 chr10:99164394 C/T cg20016023 chr10:99160130 RRP12 -0.42 -6.79 -0.34 5.08e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs34779708 0.931 rs7897457 chr10:35386040 A/G cg04310649 chr10:35416472 CREM -0.43 -5.86 -0.3 1.11e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 0.545 rs2279757 chr7:65828663 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 6.86 0.35 3.29e-11 Aortic root size; LIHC cis rs79149102 0.579 rs74023908 chr15:75310710 T/C cg15902774 chr15:75289873 SCAMP5 0.41 6.15 0.32 2.14e-9 Lung cancer; LIHC cis rs8014204 0.901 rs2080087 chr14:75365062 C/T cg08847533 chr14:75593920 NEK9 0.38 6.38 0.33 5.68e-10 Caffeine consumption; LIHC cis rs6430585 0.583 rs730005 chr2:136582694 T/C cg07169764 chr2:136633963 MCM6 1.34 21.12 0.75 5.59e-64 Corneal structure; LIHC cis rs4908768 0.501 rs7551849 chr1:8539463 A/G cg20416874 chr1:8611966 RERE -0.69 -14.74 -0.62 2.15e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs8062405 0.755 rs17707300 chr16:28593347 A/G cg07382826 chr16:28625726 SULT1A1 0.48 7.5 0.38 5.46e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg13047869 chr3:10149882 C3orf24 0.48 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC trans rs13325613 0.915 rs34005848 chr3:46263745 C/T cg26337592 chr1:153642686 ILF2 0.68 6.2 0.32 1.66e-9 Monocyte count; LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs910316 0.763 rs6574205 chr14:75453039 G/C cg08847533 chr14:75593920 NEK9 0.9 18.55 0.71 1.18e-53 Height; LIHC cis rs9419702 0.568 rs11156445 chr10:133542301 T/C cg20568497 chr10:133558893 NA 0.4 6.07 0.31 3.39e-9 Survival in rectal cancer; LIHC cis rs651907 0.535 rs1460097 chr3:101497569 C/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs7647973 0.626 rs35129566 chr3:49866584 T/G cg03060546 chr3:49711283 APEH -0.6 -7.08 -0.36 8.41e-12 Menarche (age at onset); LIHC cis rs2204008 0.846 rs2030416 chr12:38465118 A/G cg26384229 chr12:38710491 ALG10B -0.63 -9.0 -0.44 1.62e-17 Bladder cancer; LIHC cis rs921968 0.508 rs72965103 chr2:219312469 T/C cg02985541 chr2:219472218 PLCD4 -0.44 -7.18 -0.36 4.25e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs6570726 0.846 rs7773939 chr6:145927384 C/T cg13319975 chr6:146136371 FBXO30 0.37 5.82 0.3 1.34e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6831352 0.918 rs29001224 chr4:100047373 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs1005277 0.579 rs2749616 chr10:38510993 A/T cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.75 -0.3 1.94e-8 Extrinsic epigenetic age acceleration; LIHC cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg17971929 chr21:40555470 PSMG1 -0.64 -7.43 -0.37 8.78e-13 Cognitive function; LIHC cis rs7772486 0.875 rs854148 chr6:146310979 G/C cg13319975 chr6:146136371 FBXO30 -0.39 -6.3 -0.32 9.41e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06476606 chr10:91061728 IFIT2 0.49 7.28 0.37 2.34e-12 Cognitive function; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg14828511 chr1:107599125 PRMT6 0.4 5.79 0.3 1.59e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2303759 0.918 rs4802597 chr19:49872085 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.56 8.86 0.43 4.52e-17 Multiple sclerosis; LIHC cis rs4466137 1.000 rs1154888 chr5:82977410 C/A cg16102102 chr5:83017553 HAPLN1 -0.58 -8.8 -0.43 6.86e-17 Prostate cancer; LIHC cis rs9296092 0.500 rs4376348 chr6:33521097 A/G cg13560919 chr6:33536144 NA -0.39 -6.31 -0.32 8.5e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg12463550 chr7:65579703 CRCP 0.7 7.37 0.37 1.33e-12 Diabetic kidney disease; LIHC cis rs7613875 0.600 rs2856237 chr3:50158774 A/G cg05623727 chr3:50126028 RBM5 -0.36 -6.22 -0.32 1.47e-9 Body mass index; LIHC cis rs644799 1.000 rs680134 chr11:95559517 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.31 0.68 1.13e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.817 rs10839401 chr11:49876144 C/T cg03929089 chr4:120376271 NA -0.88 -18.16 -0.7 4.3e-52 Height; LIHC cis rs17376456 0.825 rs17372057 chr5:93071916 C/A cg25358565 chr5:93447407 FAM172A 1.04 9.48 0.46 4.29e-19 Diabetic retinopathy; LIHC cis rs4684776 0.867 rs60056696 chr3:11331944 C/T cg00170343 chr3:11313890 ATG7 -0.52 -7.15 -0.36 5.22e-12 Small vessel stroke; LIHC cis rs9814567 1.000 rs62271513 chr3:134298412 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.24 0.55 8.15e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9916302 0.904 rs12452880 chr17:37591149 G/C cg07936489 chr17:37558343 FBXL20 -0.84 -13.41 -0.59 2.95e-33 Glomerular filtration rate (creatinine); LIHC cis rs7945718 1.000 rs7945719 chr11:12748820 A/C cg25843174 chr11:12811716 TEAD1 0.36 8.24 0.41 3.64e-15 Educational attainment (years of education); LIHC cis rs9811920 0.609 rs793465 chr3:99627750 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs559928 0.606 rs61083753 chr11:63892665 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.7 7.26 0.37 2.62e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7095607 0.606 rs4746737 chr10:69959779 T/C cg18986048 chr10:69913749 MYPN 0.39 5.85 0.3 1.12e-8 Lung function (FVC); LIHC cis rs3096299 0.685 rs2911244 chr16:89521860 A/G cg08392591 chr16:89556376 ANKRD11 0.54 8.52 0.42 5.13e-16 Multiple myeloma (IgH translocation); LIHC cis rs11888559 0.511 rs1975211 chr2:204035715 T/C cg24605529 chr2:203879461 NBEAL1 0.76 5.81 0.3 1.44e-8 Height; LIHC trans rs6489882 0.966 rs6489879 chr12:113377822 G/A cg10175203 chr3:128143634 NA 0.38 6.18 0.32 1.8e-9 Chronic lymphocytic leukemia; LIHC cis rs422249 0.512 rs174574 chr11:61600342 A/C cg07689907 chr11:61582574 FADS1 -0.39 -5.81 -0.3 1.39e-8 Trans fatty acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19424078 chr11:747111 TALDO1 -0.44 -6.17 -0.32 1.94e-9 Pancreatic cancer; LIHC cis rs2645694 0.626 rs2703140 chr4:77830057 C/G cg06046430 chr4:77819534 ANKRD56 0.51 6.29 0.32 9.49e-10 Emphysema distribution in smoking; LIHC cis rs8180040 1.000 rs11130127 chr3:47398793 C/G cg27129171 chr3:47204927 SETD2 -0.65 -10.98 -0.51 3.07e-24 Colorectal cancer; LIHC cis rs10056811 0.510 rs10058171 chr5:74407991 C/T cg00601450 chr5:74908170 NA 0.56 6.43 0.33 4.25e-10 Coronary artery disease; LIHC cis rs2629540 0.781 rs2293064 chr10:126396511 C/G cg20435097 chr10:126320824 FAM53B -0.41 -6.16 -0.32 2.02e-9 Cocaine dependence; LIHC cis rs1018836 0.663 rs12674903 chr8:91475774 T/C cg16814680 chr8:91681699 NA -0.39 -6.27 -0.32 1.08e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs8060686 0.516 rs10852439 chr16:68288331 T/C cg05110241 chr16:68378359 PRMT7 -0.57 -6.82 -0.35 4.24e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs875971 0.660 rs7807944 chr7:66087195 C/G cg00343986 chr7:65444356 GUSB -0.39 -5.83 -0.3 1.26e-8 Aortic root size; LIHC cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs10911251 0.508 rs2296297 chr1:183105324 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.26 0.48 1.07e-21 Colorectal cancer; LIHC cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg08392591 chr16:89556376 ANKRD11 0.43 6.45 0.33 3.92e-10 Multiple myeloma (IgH translocation); LIHC cis rs6545883 0.929 rs2600663 chr2:61540687 A/G cg14146966 chr2:61757674 XPO1 -0.43 -7.29 -0.37 2.12e-12 Tuberculosis; LIHC cis rs7216064 1.000 rs12451707 chr17:65871598 G/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2153535 0.580 rs2327060 chr6:8447111 G/A cg07606381 chr6:8435919 SLC35B3 0.78 11.4 0.52 1.01e-25 Motion sickness; LIHC trans rs8073060 0.586 rs6505487 chr17:33996850 A/G cg19694781 chr19:47549865 TMEM160 -1.22 -12.9 -0.57 2.79e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7618501 0.572 rs4688756 chr3:50040194 T/A cg21467203 chr3:49911342 NA -0.43 -7.71 -0.38 1.39e-13 Intelligence (multi-trait analysis); LIHC cis rs1401999 0.836 rs34571027 chr3:183726644 T/C cg20387954 chr3:183756860 HTR3D 0.28 6.07 0.31 3.32e-9 Anterior chamber depth; LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg03721293 chr16:90014378 DEF8 0.38 6.35 0.32 6.72e-10 Skin colour saturation; LIHC cis rs7107174 0.901 rs10899500 chr11:78125246 A/G cg02023728 chr11:77925099 USP35 0.41 7.38 0.37 1.21e-12 Testicular germ cell tumor; LIHC cis rs2075371 0.933 rs1421481 chr7:133964380 A/C cg20476274 chr7:133979776 SLC35B4 0.73 12.68 0.57 1.81e-30 Mean platelet volume; LIHC cis rs12477438 0.798 rs6716913 chr2:99580641 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.07 -14.82 -0.63 1.03e-38 Chronic sinus infection; LIHC trans rs526821 0.595 rs499446 chr11:55355722 A/G cg03929089 chr4:120376271 NA -0.45 -6.85 -0.35 3.49e-11 Pediatric bone mineral density (spine); LIHC cis rs748404 0.697 rs531910 chr15:43560607 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.39 0.41 1.28e-15 Lung cancer; LIHC cis rs921968 0.541 rs585185 chr2:219457741 G/A cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.37e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs2120019 1.000 rs7175720 chr15:75348962 C/G cg11632617 chr15:75315747 PPCDC 0.47 6.83 0.35 3.86e-11 Blood trace element (Zn levels); LIHC cis rs2380220 0.808 rs2613548 chr6:95910559 C/T cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs1005277 0.579 rs9299760 chr10:38377920 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg07424592 chr7:64974309 NA -0.8 -9.32 -0.45 1.44e-18 Diabetic kidney disease; LIHC cis rs4819852 0.958 rs2238792 chr22:19983213 C/T cg07821417 chr22:19972146 ARVCF 0.47 6.92 0.35 2.31e-11 Pulse pressure; LIHC cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.74 -8.96 -0.44 2.11e-17 Gut microbiome composition (summer); LIHC cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg18252515 chr7:66147081 NA 1.24 16.09 0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs910316 0.763 rs175036 chr14:75464295 C/T cg08847533 chr14:75593920 NEK9 -0.87 -17.87 -0.69 6.79e-51 Height; LIHC cis rs1670533 1.000 rs13119276 chr4:1051574 T/C cg27284194 chr4:1044797 NA 0.6 9.02 0.44 1.36e-17 Recombination rate (females); LIHC cis rs7100689 0.784 rs7082102 chr10:82104890 A/C cg01528321 chr10:82214614 TSPAN14 0.85 11.62 0.53 1.51e-26 Post bronchodilator FEV1; LIHC cis rs4474465 1.000 rs6592779 chr11:78197283 G/C cg02023728 chr11:77925099 USP35 0.36 6.24 0.32 1.3e-9 Alzheimer's disease (survival time); LIHC cis rs709400 0.663 rs62007718 chr14:103940436 G/A cg26031613 chr14:104095156 KLC1 0.75 9.7 0.46 8.48e-20 Body mass index; LIHC cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg23758822 chr17:41437982 NA 0.95 17.58 0.69 9.65e-50 Menopause (age at onset); LIHC cis rs4927850 0.958 rs2044599 chr3:195736740 G/A cg12923728 chr3:195709715 SDHAP1 -0.74 -9.86 -0.47 2.43e-20 Pancreatic cancer; LIHC cis rs9902453 0.765 rs2729436 chr17:28120670 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs3749237 0.615 rs55957735 chr3:49438158 G/A cg07636037 chr3:49044803 WDR6 0.5 7.53 0.38 4.44e-13 Resting heart rate; LIHC cis rs6912958 0.712 rs2787927 chr6:88412786 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.39 -6.67 -0.34 1.01e-10 Monocyte percentage of white cells; LIHC cis rs11718455 0.960 rs6781618 chr3:44001933 C/T cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs11229555 0.645 rs11560908 chr11:58434545 A/C cg15696309 chr11:58395628 NA 0.63 6.07 0.31 3.32e-9 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7584330 0.868 rs7571898 chr2:238383028 T/C cg14458575 chr2:238380390 NA 0.43 6.68 0.34 9.84e-11 Prostate cancer; LIHC cis rs7582720 1.000 rs72934715 chr2:203713280 C/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.98 0.31 5.56e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg08280861 chr8:58055591 NA 0.52 6.5 0.33 2.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs9328483 chr6:8521295 A/G cg21535247 chr6:8435926 SLC35B3 0.63 8.31 0.41 2.3e-15 Motion sickness; LIHC cis rs796364 0.539 rs6738494 chr2:200697058 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.6 6.28 0.32 1.06e-9 Schizophrenia; LIHC cis rs965469 0.744 rs6139093 chr20:3334838 A/G cg25506879 chr20:3388711 C20orf194 -0.52 -6.41 -0.33 4.8e-10 IFN-related cytopenia; LIHC cis rs4969178 0.965 rs12450528 chr17:76395753 G/A cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs4319547 0.695 rs10773152 chr12:122910180 T/C cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.55 -0.38 3.9e-13 Body mass index; LIHC cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg12463550 chr7:65579703 CRCP 0.69 7.12 0.36 6.23e-12 Diabetic kidney disease; LIHC cis rs12950390 0.853 rs56363619 chr17:45854621 T/C cg03474202 chr17:45855739 NA -0.34 -5.9 -0.3 8.75e-9 IgG glycosylation; LIHC cis rs344364 0.511 rs2982447 chr16:1947413 C/T cg26897989 chr16:1907736 C16orf73 0.49 6.18 0.32 1.87e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs4891159 0.790 rs11872411 chr18:74132051 C/T cg24786174 chr18:74118243 ZNF516 -0.77 -14.06 -0.61 9.76e-36 Longevity; LIHC cis rs4803468 0.967 rs3213860 chr19:41920211 T/C cg14132834 chr19:41945861 ATP5SL -0.45 -6.6 -0.34 1.61e-10 Height; LIHC trans rs6952808 0.723 rs4721282 chr7:2025040 A/G cg04565464 chr8:145669602 NFKBIL2 0.39 6.51 0.33 2.63e-10 Bipolar disorder and schizophrenia; LIHC cis rs6570726 0.846 rs371186 chr6:145886971 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.2e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6466055 0.777 rs11765045 chr7:104922115 T/A cg04380332 chr7:105027541 SRPK2 0.37 6.86 0.35 3.2e-11 Schizophrenia; LIHC cis rs1559088 1.000 rs7256328 chr19:33558705 G/C cg27124370 chr19:33622961 WDR88 0.47 7.09 0.36 7.77e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg22800045 chr5:56110881 MAP3K1 0.69 8.66 0.42 1.89e-16 Initial pursuit acceleration; LIHC cis rs9911578 0.967 rs72628392 chr17:56506160 A/G cg05425664 chr17:57184151 TRIM37 0.57 8.53 0.42 4.87e-16 Intelligence (multi-trait analysis); LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.09 -0.31 3.09e-9 Total body bone mineral density; LIHC cis rs778371 0.522 rs6704768 chr2:233592501 C/T cg08000102 chr2:233561755 GIGYF2 0.75 12.48 0.56 9.93e-30 Schizophrenia; LIHC cis rs8180040 0.966 rs6800271 chr3:47470787 A/T cg16586182 chr3:47516702 SCAP 0.58 11.61 0.53 1.71e-26 Colorectal cancer; LIHC cis rs9818758 0.607 rs34566463 chr3:49245077 T/C cg07636037 chr3:49044803 WDR6 -0.8 -8.16 -0.4 6.27e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2842992 0.673 rs6930904 chr6:160217433 T/A cg16489826 chr6:160211363 TCP1;MRPL18 0.53 9.12 0.44 6.35e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs6952808 0.862 rs4721135 chr7:1912222 A/G cg21782813 chr7:2030301 MAD1L1 0.38 6.4 0.33 5.2400000000000005e-10 Bipolar disorder and schizophrenia; LIHC cis rs922107 0.967 rs2045583 chr1:90018974 G/T cg15422784 chr1:90023713 LRRC8B 0.49 8.08 0.4 1.11e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G ch.8.15787776F chr8:15743405 NA -0.52 -6.16 -0.32 2.05e-9 Preeclampsia; LIHC cis rs7903847 0.646 rs10882924 chr10:99159304 T/A cg08345082 chr10:99160200 RRP12 -0.39 -6.72 -0.34 7.76e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg06873352 chr17:61820015 STRADA 0.73 13.33 0.58 6.02e-33 Prudent dietary pattern; LIHC cis rs9457247 0.765 rs9459849 chr6:167444160 G/T cg07741184 chr6:167504864 NA 0.31 7.09 0.36 7.82e-12 Crohn's disease; LIHC cis rs2282032 0.527 rs55664487 chr14:90765880 C/T cg04374321 chr14:90722782 PSMC1 0.49 7.07 0.36 8.56e-12 Longevity; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg07677032 chr17:61819896 STRADA 0.44 6.3 0.32 9.29e-10 Prudent dietary pattern; LIHC cis rs875971 0.545 rs801212 chr7:66015630 C/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.35 -7.0 -0.35 1.34e-11 Aortic root size; LIHC cis rs58688157 0.883 rs7936397 chr11:577534 G/A cg01842473 chr11:617407 IRF7;MUPCDH -0.56 -5.91 -0.3 8.14e-9 Systemic lupus erythematosus; LIHC cis rs11098499 0.865 rs2389809 chr4:120377399 T/C cg09307838 chr4:120376055 NA 0.79 12.54 0.56 5.98e-30 Corneal astigmatism; LIHC cis rs11628318 0.614 rs1190338 chr14:103105792 T/G cg23461800 chr14:103021989 NA -0.42 -5.87 -0.3 1.03e-8 Platelet count; LIHC cis rs2075371 0.611 rs35428392 chr7:134019645 G/A cg20476274 chr7:133979776 SLC35B4 0.48 6.39 0.33 5.31e-10 Mean platelet volume; LIHC trans rs1005277 0.505 rs200910 chr10:38108176 C/T cg27523141 chr10:43048294 ZNF37B 0.39 6.86 0.35 3.25e-11 Extrinsic epigenetic age acceleration; LIHC cis rs826838 0.709 rs4882355 chr12:38721462 A/T cg26384229 chr12:38710491 ALG10B 0.56 7.71 0.38 1.4e-13 Heart rate; LIHC cis rs2243480 0.901 rs778732 chr7:65822360 C/T cg07424592 chr7:64974309 NA 0.78 9.13 0.44 5.98e-18 Diabetic kidney disease; LIHC trans rs1005277 0.540 rs289638 chr10:37923731 G/A cg27523141 chr10:43048294 ZNF37B 0.39 6.79 0.34 5.12e-11 Extrinsic epigenetic age acceleration; LIHC cis rs11252926 0.574 rs10904065 chr10:423226 G/T cg18196295 chr10:418757 DIP2C -0.51 -5.89 -0.3 9.07e-9 Psychosis in Alzheimer's disease; LIHC cis rs9993613 0.967 rs6446841 chr4:73437856 C/G cg15102770 chr4:73434591 ADAMTS3 -0.38 -6.02 -0.31 4.55e-9 Hip circumference adjusted for BMI;Height; LIHC trans rs10761482 0.500 rs10821779 chr10:62274525 A/G cg14898824 chr12:64851143 TBK1 -0.33 -6.23 -0.32 1.36e-9 Schizophrenia; LIHC cis rs15676 0.783 rs2977998 chr9:131580570 A/G cg00228799 chr9:131580591 ENDOG 0.49 7.0 0.35 1.35e-11 Blood metabolite levels; LIHC cis rs546131 0.642 rs561477 chr11:34852152 G/A cg06937548 chr11:34938143 PDHX;APIP 0.58 7.52 0.38 4.95e-13 Lung disease severity in cystic fibrosis; LIHC cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg24101359 chr6:42928495 GNMT 0.44 5.96 0.31 6.43e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1538970 0.816 rs61788356 chr1:46006675 C/T cg24296786 chr1:45957014 TESK2 -0.47 -6.31 -0.32 8.88e-10 Platelet count; LIHC cis rs7267979 1.000 rs2258066 chr20:25271326 C/T cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs9810089 0.777 rs2688601 chr3:136252601 G/A cg21827317 chr3:136751795 NA 0.45 6.03 0.31 4.34e-9 Gestational age at birth (child effect); LIHC cis rs2963155 0.518 rs1438732 chr5:142756266 G/C cg17617527 chr5:142782415 NR3C1 0.93 10.4 0.49 3.5e-22 Breast cancer; LIHC cis rs2204008 0.577 rs11520050 chr12:38051839 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.89 -0.3 9.34e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7095607 0.538 rs2255027 chr10:69920911 T/C cg18986048 chr10:69913749 MYPN 0.49 7.33 0.37 1.65e-12 Lung function (FVC); LIHC cis rs2932538 0.922 rs3790612 chr1:113084146 G/A cg22162597 chr1:113214053 CAPZA1 0.69 10.6 0.5 6.92e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1144333 0.737 rs1144339 chr1:76280543 A/G cg10523679 chr1:76189770 ACADM -0.46 -6.73 -0.34 7.26e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs7572733 0.534 rs700684 chr2:198713099 C/T cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs911119 1.000 rs6114208 chr20:23621734 C/G cg16589663 chr20:23618590 CST3 0.77 8.2 0.41 4.92e-15 Chronic kidney disease; LIHC cis rs853679 0.517 rs67878650 chr6:28142587 G/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.75e-10 Depression; LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.78 -0.34 5.36e-11 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17839278 chr11:47664375 MTCH2 0.47 6.33 0.32 7.88e-10 Pancreatic cancer; LIHC cis rs919433 0.679 rs10203581 chr2:198515900 G/A cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.46e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7249142 0.562 rs1050544 chr19:19287901 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.79 -0.34 4.85e-11 IgG glycosylation; LIHC cis rs9768139 0.733 rs10156158 chr7:158122287 G/T cg25566285 chr7:158114605 PTPRN2 0.23 6.2 0.32 1.66e-9 Calcium levels; LIHC trans rs6952808 0.771 rs10244946 chr7:1921068 A/G cg04565464 chr8:145669602 NFKBIL2 -0.39 -6.35 -0.32 6.91e-10 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.676 rs13098228 chr3:47138253 A/G cg16586182 chr3:47516702 SCAP -0.51 -9.23 -0.45 2.94e-18 Colorectal cancer; LIHC cis rs2932538 0.883 rs6701351 chr1:113139196 G/A cg22162597 chr1:113214053 CAPZA1 0.68 10.69 0.5 3.3e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7618501 1.000 rs11130219 chr3:49752427 C/T cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.681 rs1976901 chr11:49378697 T/C cg18944383 chr4:111397179 ENPEP 0.26 6.25 0.32 1.23e-9 Coronary artery disease; LIHC cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg12311346 chr5:56204834 C5orf35 -0.56 -7.37 -0.37 1.27e-12 Initial pursuit acceleration; LIHC cis rs7027203 0.717 rs7869328 chr9:96588782 A/G cg13679303 chr9:96623674 NA -0.28 -6.09 -0.31 3.03e-9 DNA methylation (variation); LIHC cis rs921968 0.541 rs4674308 chr2:219310483 A/C cg18887096 chr2:219472410 PLCD4 0.39 5.96 0.31 6.15e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs9549328 0.800 rs9549616 chr13:113627762 T/G cg08890338 chr13:113700818 MCF2L -0.36 -5.83 -0.3 1.3e-8 Systolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07372840 chr5:180296196 NA 0.42 6.25 0.32 1.19e-9 Cognitive function; LIHC cis rs6752107 0.967 rs10203952 chr2:234153366 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.51 7.73 0.39 1.21e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4319547 0.774 rs7295105 chr12:123124225 G/A cg05707623 chr12:122985044 ZCCHC8 -0.5 -6.86 -0.35 3.24e-11 Body mass index; LIHC cis rs7684446 1 rs7684446 chr4:15592864 C/T cg16509355 chr4:15471240 CC2D2A 0.41 6.58 0.34 1.73e-10 Red blood cell count; LIHC cis rs6500602 0.739 rs4786502 chr16:4537104 T/C cg08645402 chr16:4508243 NA 0.45 8.57 0.42 3.63e-16 Schizophrenia; LIHC cis rs13064411 0.696 rs6798938 chr3:113218206 C/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs7408868 1.000 rs8107180 chr19:15275430 T/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.79 -0.3 1.61e-8 Pulse pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13396037 chr8:42996139 HGSNAT 0.48 6.62 0.34 1.42e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs77633900 0.772 rs284902 chr15:76745687 G/C cg21673338 chr15:77095150 SCAPER -0.53 -5.93 -0.31 7.23e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs2070433 0.851 rs8129793 chr21:47925719 T/C cg12379764 chr21:47803548 PCNT 0.59 8.4 0.41 1.17e-15 Lymphocyte counts; LIHC cis rs6089584 0.853 rs1740367 chr20:60574834 C/T cg06108461 chr20:60628389 TAF4 -0.96 -15.12 -0.63 6.68e-40 Body mass index; LIHC cis rs7647973 0.626 rs62260723 chr3:49872124 T/C cg03060546 chr3:49711283 APEH -0.6 -6.97 -0.35 1.69e-11 Menarche (age at onset); LIHC cis rs55702914 0.710 rs1429419 chr2:198154547 G/A cg10820045 chr2:198174542 NA -0.4 -6.03 -0.31 4.23e-9 Major depression and alcohol dependence; LIHC cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg25364880 chr3:44379878 C3orf23 0.5 7.17 0.36 4.61e-12 Depressive symptoms; LIHC cis rs546131 0.642 rs1039841 chr11:34833139 A/G cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.59 -0.34 1.66e-10 Lung disease severity in cystic fibrosis; LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg05025164 chr4:1340916 KIAA1530 0.76 11.82 0.54 2.78e-27 Longevity; LIHC cis rs1043515 0.748 rs11657530 chr17:36942814 T/C cg20826740 chr17:37024042 NA 0.41 6.9 0.35 2.6e-11 Height; LIHC cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg11301795 chr4:187892539 NA -0.27 -7.03 -0.36 1.1e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs644799 0.540 rs10831422 chr11:95478968 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.8 12.3 0.55 4.89e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11758351 0.866 rs55815656 chr6:26207303 G/A cg16070018 chr6:26224392 HIST1H3E 0.6 7.53 0.38 4.45e-13 Gout;Renal underexcretion gout; LIHC cis rs11122272 0.735 rs2808597 chr1:231532351 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 6.98e-23 Hemoglobin concentration; LIHC cis rs1008375 0.931 rs7435102 chr4:17571480 C/G cg16339924 chr4:17578868 LAP3 0.43 5.73 0.3 2.17e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs13191362 0.935 rs34141091 chr6:162953893 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.76 0.3 1.92e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs986417 0.818 rs2057135 chr14:61077022 G/A cg27398547 chr14:60952738 C14orf39 0.66 7.31 0.37 1.93e-12 Gut microbiota (bacterial taxa); LIHC cis rs9517320 0.534 rs9554477 chr13:99160379 C/T cg20487152 chr13:99095054 FARP1 -0.36 -6.14 -0.32 2.28e-9 Longevity; LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg06481639 chr22:41940642 POLR3H -0.69 -6.99 -0.35 1.45e-11 Vitiligo; LIHC cis rs7769051 0.803 rs12193474 chr6:133186168 T/C cg22852734 chr6:133119734 C6orf192 0.83 7.39 0.37 1.13e-12 Type 2 diabetes nephropathy; LIHC cis rs10464366 0.544 rs4540324 chr7:39185299 G/C cg18850127 chr7:39170497 POU6F2 0.45 8.07 0.4 1.2e-14 IgG glycosylation; LIHC cis rs875971 0.545 rs7811204 chr7:65852200 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 6.86 0.35 3.29e-11 Aortic root size; LIHC cis rs9733 0.596 rs11204697 chr1:150658971 C/T cg17724175 chr1:150552817 MCL1 0.48 9.6 0.46 1.72e-19 Tonsillectomy; LIHC cis rs7980687 0.657 rs2851447 chr12:123665113 G/C cg00376283 chr12:123451042 ABCB9 0.7 10.64 0.5 4.85e-23 Height;Educational attainment;Head circumference (infant); LIHC cis rs477895 0.713 rs12787852 chr11:63954648 G/A cg05555928 chr11:63887634 MACROD1 0.5 6.53 0.33 2.34e-10 Mean platelet volume; LIHC cis rs875971 0.545 rs1065265 chr7:65841203 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 6.86 0.35 3.29e-11 Aortic root size; LIHC trans rs62103177 1.000 rs62103177 chr18:77624479 G/A cg05926928 chr17:57297772 GDPD1 1.1 11.28 0.52 2.73e-25 Opioid sensitivity; LIHC trans rs1814175 0.817 rs11040700 chr11:50023832 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01151424 chr11:17411006 KCNJ11 0.47 7.0 0.35 1.34e-11 Lung function (FEV1/FVC); LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg07157834 chr1:205819609 PM20D1 0.65 9.71 0.46 7.5599999999999994e-20 Menarche (age at onset); LIHC cis rs3540 0.533 rs11633692 chr15:91056043 G/A cg22089800 chr15:90895588 ZNF774 -0.55 -7.76 -0.39 9.73e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs8017423 1.000 rs8017423 chr14:90679910 A/G cg14092571 chr14:90743983 NA -0.38 -5.97 -0.31 5.93e-9 Mortality in heart failure; LIHC cis rs7552404 0.924 rs114752222 chr1:76180878 C/T cg22875332 chr1:76189707 ACADM 0.48 7.47 0.37 6.73e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7777484 0.571 rs2527686 chr7:2834413 G/A cg19717773 chr7:2847554 GNA12 -0.44 -8.76 -0.43 9.07e-17 Height; LIHC cis rs9486719 0.948 rs11152952 chr6:96894303 A/G cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs1707322 0.627 rs3014213 chr1:46045522 T/C cg24296786 chr1:45957014 TESK2 0.42 5.78 0.3 1.64e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12744310 1.000 rs12032162 chr1:41762935 T/C cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2625529 0.824 rs4776581 chr15:72207071 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.75 -0.3 1.98e-8 Red blood cell count; LIHC cis rs1707322 0.896 rs785512 chr1:46534543 A/G cg06784218 chr1:46089804 CCDC17 -0.38 -6.75 -0.34 6.19e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10028773 0.600 rs4001390 chr4:120265783 G/C cg09307838 chr4:120376055 NA 0.63 9.88 0.47 2.07e-20 Educational attainment; LIHC cis rs9473924 0.542 rs2857514 chr6:50811283 C/T cg14470998 chr6:50812995 TFAP2B 1.05 8.9 0.43 3.3e-17 Body mass index; LIHC trans rs12752401 0.867 rs67349818 chr1:103030560 T/C cg24921808 chr19:740313 PALM 0.49 6.43 0.33 4.21e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg13409248 chr3:40428643 ENTPD3 0.49 8.24 0.41 3.69e-15 Renal cell carcinoma; LIHC cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg15691649 chr6:25882328 NA -0.39 -6.22 -0.32 1.44e-9 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05793409 chr1:35658810 SFPQ 0.42 6.15 0.32 2.13e-9 Pancreatic cancer; LIHC cis rs12701220 0.553 rs9639882 chr7:1133731 G/A cg18765753 chr7:1198926 ZFAND2A -0.42 -5.95 -0.31 6.46e-9 Bronchopulmonary dysplasia; LIHC cis rs882732 1.000 rs875958 chr14:95028667 A/T cg14866387 chr14:95027382 SERPINA4 -0.44 -6.36 -0.33 6.61e-10 Blood protein levels; LIHC cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 11.67 0.53 1.02e-26 Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04318546 chr15:101147087 ASB7 -0.41 -6.22 -0.32 1.44e-9 Lung function (FEV1/FVC); LIHC cis rs6860806 0.507 rs272880 chr5:131670178 C/T cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.82e-31 Breast cancer; LIHC cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg22508957 chr16:3507546 NAT15 -0.48 -9.29 -0.45 1.91e-18 Tuberculosis; LIHC cis rs1046896 0.961 rs7208565 chr17:80696692 C/T cg00809820 chr17:80708513 TBCD;FN3K 0.34 5.93 0.31 7.53e-9 Glycated hemoglobin levels; LIHC cis rs2204008 0.660 rs2874343 chr12:38239096 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.85 0.3 1.14e-8 Bladder cancer; LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs963731 0.649 rs297143 chr2:39320067 T/C cg04010122 chr2:39346883 SOS1 -0.68 -6.03 -0.31 4.15e-9 Corticobasal degeneration; LIHC cis rs1008375 1.000 rs10019856 chr4:17615742 T/A cg15017067 chr4:17643749 FAM184B 0.34 5.75 0.3 2.02e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6088590 0.502 rs6059861 chr20:33068563 A/T cg08999081 chr20:33150536 PIGU 0.67 13.32 0.58 6.74e-33 Coronary artery disease; LIHC trans rs875971 0.867 rs13227219 chr7:65844062 T/A cg10756647 chr7:56101905 PSPH 0.47 6.81 0.35 4.38e-11 Aortic root size; LIHC cis rs57590327 0.555 rs6767749 chr3:81725513 G/A cg07356753 chr3:81810745 GBE1 -0.52 -8.01 -0.4 1.81e-14 Extraversion; LIHC cis rs3812111 0.774 rs482012 chr6:116430533 G/T cg08036074 chr6:116424633 NT5DC1 0.66 11.82 0.54 2.97e-27 Age-related macular degeneration; LIHC cis rs3731896 0.848 rs4485556 chr2:220157418 A/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.57 7.51 0.38 5.05e-13 Educational attainment; LIHC cis rs77633900 0.614 rs2468122 chr15:76918686 A/C cg21673338 chr15:77095150 SCAPER -0.46 -6.74 -0.34 6.89e-11 Non-glioblastoma glioma;Glioma; LIHC cis rs748404 0.631 rs1133395 chr15:43650384 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.55 9.73 0.47 6.35e-20 Lung cancer; LIHC cis rs4700695 0.534 rs153394 chr5:65426676 T/A cg21114390 chr5:65439923 SFRS12 -0.52 -6.06 -0.31 3.63e-9 Facial morphology (factor 19); LIHC cis rs1865721 0.804 rs719179 chr18:73146396 A/G cg26385618 chr18:73139727 C18orf62 -0.3 -7.88 -0.39 4.27e-14 Intelligence; LIHC cis rs7727544 0.661 rs273900 chr5:131694606 G/A cg24060327 chr5:131705240 SLC22A5 -0.57 -8.27 -0.41 2.98e-15 Blood metabolite levels; LIHC cis rs7617480 0.648 rs4974083 chr3:49000626 A/G cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.24 0.32 1.31e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs4901869 0.932 rs12878445 chr14:59339361 A/G cg02291164 chr14:59296302 NA 0.47 6.07 0.31 3.48e-9 Panic disorder; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs6088590 1.000 rs28542147 chr20:33376323 G/A cg24642439 chr20:33292090 TP53INP2 0.78 10.6 0.5 6.72e-23 Coronary artery disease; LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.77 0.62 1.56e-38 Prudent dietary pattern; LIHC cis rs2070433 0.660 rs11701034 chr21:47793235 A/G cg12379764 chr21:47803548 PCNT 0.76 10.92 0.51 5.27e-24 Lymphocyte counts; LIHC cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg25894440 chr7:65020034 NA -0.6 -6.45 -0.33 3.93e-10 Diabetic kidney disease; LIHC cis rs5769765 0.908 rs4058453 chr22:50250297 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.61 5.99 0.31 5.3e-9 Schizophrenia; LIHC cis rs734999 0.505 rs4648659 chr1:2560903 T/G cg18854424 chr1:2615690 NA -0.33 -7.2 -0.36 3.87e-12 Ulcerative colitis; LIHC cis rs3020736 0.500 rs1801311 chr22:42486723 G/A cg15557168 chr22:42548783 NA 0.43 6.68 0.34 9.5e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs35883536 1.000 rs2491822 chr1:101115839 T/C cg14515779 chr1:101123966 NA 0.63 12.13 0.55 2.12e-28 Monocyte count; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.73 0.57 1.17e-30 Prudent dietary pattern; LIHC cis rs739401 0.527 rs418832 chr11:3072236 C/T cg05729581 chr11:3078854 CARS -0.45 -6.14 -0.32 2.27e-9 Longevity; LIHC cis rs875971 0.830 rs7799834 chr7:65880694 A/C cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs7615952 0.576 rs4646763 chr3:125822129 G/A cg05084668 chr3:125655381 ALG1L -0.4 -6.04 -0.31 4.12e-9 Blood pressure (smoking interaction); LIHC cis rs6540556 0.723 rs12034758 chr1:209920545 G/A cg05527609 chr1:210001259 C1orf107 -0.68 -9.37 -0.45 9.78e-19 Red blood cell count; LIHC trans rs11098499 0.955 rs13129661 chr4:120152909 C/G cg25214090 chr10:38739885 LOC399744 0.54 8.06 0.4 1.32e-14 Corneal astigmatism; LIHC cis rs2404602 1.000 rs2056544 chr15:76826003 G/A cg23625390 chr15:77176239 SCAPER 0.4 6.74 0.34 6.57e-11 Blood metabolite levels; LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg16145915 chr7:1198662 ZFAND2A -0.4 -10.25 -0.48 1.14e-21 Longevity;Endometriosis; LIHC trans rs783540 0.967 rs1269134 chr15:83282628 T/C cg18393722 chr15:85113863 UBE2QP1 -0.39 -6.69 -0.34 8.99e-11 Schizophrenia; LIHC cis rs4803468 1.000 rs284648 chr19:41926790 T/C cg09537434 chr19:41945824 ATP5SL -1.03 -21.43 -0.76 3.5e-65 Height; LIHC cis rs9457247 0.663 rs2301436 chr6:167437988 C/T cg07741184 chr6:167504864 NA 0.26 6.17 0.32 1.9e-9 Crohn's disease; LIHC cis rs2180341 1.000 rs3798852 chr6:127636733 A/G cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs922107 0.738 rs12135419 chr1:90053245 C/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.69 -0.38 1.58e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg16132339 chr22:24313637 DDTL;DDT -0.74 -13.72 -0.6 1.97e-34 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs35110281 0.774 rs1003280 chr21:44997322 A/G cg01579765 chr21:45077557 HSF2BP -0.35 -6.6 -0.34 1.57e-10 Mean corpuscular volume; LIHC cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.92 -0.39 3.35e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg21448741 chr8:58168803 NA 0.34 6.13 0.31 2.42e-9 Developmental language disorder (linguistic errors); LIHC cis rs7618501 0.669 rs2230590 chr3:49936102 T/C cg21467203 chr3:49911342 NA -0.49 -8.59 -0.42 3.1e-16 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.11 -0.31 2.77e-9 Total body bone mineral density; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.77 0.8 2.76e-78 Prudent dietary pattern; LIHC cis rs2637266 0.756 rs846631 chr10:78536928 T/G cg18941641 chr10:78392320 NA 0.28 5.96 0.31 6.3e-9 Pulmonary function; LIHC cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs4243830 0.850 rs10779787 chr1:6599755 C/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.84 -9.45 -0.46 5.47e-19 Body mass index; LIHC cis rs754466 0.651 rs10762767 chr10:79645070 C/A cg17075019 chr10:79541650 NA -0.73 -11.06 -0.51 1.66e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs861020 0.677 rs2049998 chr1:210031154 C/T cg09163369 chr1:210001066 C1orf107 -0.5 -5.82 -0.3 1.33e-8 Orofacial clefts; LIHC cis rs7584330 0.744 rs72620822 chr2:238379582 C/T cg14458575 chr2:238380390 NA 0.56 8.21 0.41 4.64e-15 Prostate cancer; LIHC cis rs425277 0.583 rs3107151 chr1:2051513 T/G cg04315214 chr1:2043799 PRKCZ 0.45 7.15 0.36 5.21e-12 Height; LIHC trans rs801193 1.000 rs2707854 chr7:66212597 G/A cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.89e-11 Aortic root size; LIHC cis rs9513627 0.573 rs4771336 chr13:100210610 T/G cg25919922 chr13:100150906 NA 1.01 16.82 0.67 1.09e-46 Obesity-related traits; LIHC cis rs477692 0.648 rs10829599 chr10:131321881 C/T cg19680672 chr10:131412579 MGMT -0.38 -5.8 -0.3 1.47e-8 Response to temozolomide; LIHC cis rs7408868 1.000 rs4809029 chr19:15273248 A/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs7552404 0.731 rs1689275 chr1:76409655 T/C cg03433033 chr1:76189801 ACADM -0.55 -6.56 -0.33 1.97e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9325144 0.625 rs12227353 chr12:38734542 C/T cg26384229 chr12:38710491 ALG10B -0.56 -7.67 -0.38 1.81e-13 Morning vs. evening chronotype; LIHC trans rs916888 0.821 rs199509 chr17:44858728 G/A cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs8062405 0.722 rs3785354 chr16:28550667 C/T cg07451762 chr16:28383216 NA 0.39 6.89 0.35 2.72e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9733 0.543 rs72702558 chr1:150683251 G/A cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs2204008 0.502 rs2387275 chr12:38142836 G/A cg13010199 chr12:38710504 ALG10B 0.5 5.89 0.3 9.27e-9 Bladder cancer; LIHC cis rs7615952 0.673 rs35955861 chr3:125626201 T/C cg05084668 chr3:125655381 ALG1L -0.8 -10.62 -0.5 6.05e-23 Blood pressure (smoking interaction); LIHC cis rs763121 0.853 rs138702 chr22:39132601 A/T cg06022373 chr22:39101656 GTPBP1 -0.71 -13.9 -0.6 3.76e-35 Menopause (age at onset); LIHC cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.73 0.39 1.2e-13 Electroencephalogram traits; LIHC cis rs875971 0.964 rs2277911 chr7:65958625 T/G cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs11931598 0.514 rs10937779 chr4:7039326 G/A cg26116260 chr4:7069785 GRPEL1 0.62 11.42 0.53 8.58e-26 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs72781680 0.898 rs17462558 chr2:24020812 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21227347 chr9:117374170 C9orf91 0.43 6.68 0.34 9.53e-11 Pancreatic cancer; LIHC cis rs7512552 0.839 rs2647373 chr1:150320570 G/C cg15654264 chr1:150340011 RPRD2 0.7 11.58 0.53 2.26e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs8180040 0.620 rs2278963 chr3:47054869 G/T cg27129171 chr3:47204927 SETD2 -0.57 -9.34 -0.45 1.3e-18 Colorectal cancer; LIHC cis rs765787 0.530 rs28396110 chr15:45536909 A/G cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs909002 1.000 rs2292993 chr1:32140733 C/T cg13919466 chr1:32135498 COL16A1 -0.38 -7.29 -0.37 2.11e-12 Intelligence (multi-trait analysis); LIHC cis rs4699052 0.963 rs11097804 chr4:104215137 A/T cg16532752 chr4:104119610 CENPE -0.4 -6.37 -0.33 6.09e-10 Testicular germ cell tumor; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.86 0.39 5.21e-14 Prudent dietary pattern; LIHC cis rs3741404 0.609 rs641430 chr11:63869531 C/T cg05016508 chr11:63871570 FLRT1;MACROD1 -0.42 -6.69 -0.34 9.14e-11 Platelet count; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg00280220 chr17:61926910 NA 0.42 6.89 0.35 2.73e-11 Prudent dietary pattern; LIHC cis rs1451375 0.572 rs745042 chr7:50544138 A/G cg14593290 chr7:50529359 DDC -0.61 -9.62 -0.46 1.48e-19 Malaria; LIHC cis rs9473924 0.542 rs2817378 chr6:50789197 G/A cg14470998 chr6:50812995 TFAP2B 0.99 11.04 0.51 1.92e-24 Body mass index; LIHC cis rs3845702 0.736 rs12465592 chr2:180862654 C/G cg01881094 chr2:180872142 CWC22 1.12 9.94 0.47 1.24e-20 Schizophrenia; LIHC cis rs17685 0.753 rs869806 chr7:75688623 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.37 -6.14 -0.32 2.31e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3741404 0.609 rs687581 chr11:63871533 G/T cg18225595 chr11:63971243 STIP1 -0.46 -7.35 -0.37 1.49e-12 Platelet count; LIHC cis rs7487075 0.619 rs12822345 chr12:46834677 G/C cg23829395 chr12:46796953 NA 0.35 6.19 0.32 1.76e-9 Itch intensity from mosquito bite; LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg04013166 chr16:89971882 TCF25 0.56 7.0 0.35 1.35e-11 Skin colour saturation; LIHC cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg22633049 chr21:46681294 NA -0.37 -6.36 -0.33 6.37e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1538970 0.961 rs7553318 chr1:45843086 A/G cg05343316 chr1:45956843 TESK2 0.59 8.84 0.43 5.17e-17 Platelet count; LIHC cis rs4478037 0.822 rs9865342 chr3:33118631 G/A cg16652328 chr3:33138982 GLB1;TMPPE -0.55 -7.04 -0.36 1.08e-11 Major depressive disorder; LIHC cis rs60871478 0.636 rs73045423 chr7:893952 G/A cg05535760 chr7:792225 HEATR2 -0.81 -6.59 -0.34 1.63e-10 Cerebrospinal P-tau181p levels; LIHC cis rs5769765 0.773 rs9616391 chr22:50314573 C/T cg26441486 chr22:50317300 CRELD2 0.37 5.96 0.31 6.29e-9 Schizophrenia; LIHC cis rs2070488 0.804 rs35463537 chr3:38498248 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.76 12.75 0.57 1.01e-30 Electrocardiographic conduction measures; LIHC cis rs79149102 0.579 rs12592477 chr15:75292699 C/T cg16226627 chr15:75307476 SCAMP5 0.55 9.7 0.46 8.07e-20 Lung cancer; LIHC cis rs6137287 0.722 rs1007226 chr20:21103987 A/G cg04219410 chr20:21106687 PLK1S1 0.34 5.9 0.3 8.59e-9 Height; LIHC cis rs7131987 0.903 rs2194519 chr12:29423583 C/T cg16970926 chr12:29381810 FAR2 -0.28 -5.8 -0.3 1.48e-8 QT interval; LIHC cis rs7027203 0.797 rs4744294 chr9:96612114 C/G cg14396892 chr9:96623032 NA -0.33 -6.3 -0.32 9.01e-10 DNA methylation (variation); LIHC cis rs6089584 0.853 rs1746280 chr20:60577821 C/G cg13770153 chr20:60521292 NA -0.37 -7.11 -0.36 6.84e-12 Body mass index; LIHC cis rs35791980 0.820 rs11764672 chr7:76949191 C/T cg12876866 chr7:77025528 PION -0.48 -6.54 -0.33 2.19e-10 Pursuit maintenance gain; LIHC cis rs6831352 0.918 rs29001231 chr4:100046680 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs919433 0.680 rs1961558 chr2:198487278 C/T cg10820045 chr2:198174542 NA 0.5 7.88 0.39 4.49e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4908760 0.827 rs10864360 chr1:8724522 C/T cg20416874 chr1:8611966 RERE -0.64 -12.62 -0.56 3.04e-30 Vitiligo; LIHC cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg23221052 chr5:179740743 GFPT2 -0.43 -6.14 -0.32 2.27e-9 Height; LIHC cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg13770153 chr20:60521292 NA -0.35 -7.06 -0.36 9.2e-12 Body mass index; LIHC cis rs6754311 0.593 rs10186843 chr2:136586958 C/A cg17750252 chr2:136567154 LCT 0.33 5.93 0.31 7.44e-9 Mosquito bite size; LIHC cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg18305652 chr10:134549665 INPP5A 0.44 6.44 0.33 3.99e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7223966 0.921 rs34699959 chr17:61960720 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.52 0.33 2.51e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs769267 0.896 rs7250893 chr19:19625547 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.5 7.6 0.38 2.93e-13 Tonsillectomy; LIHC cis rs7618501 0.633 rs2252833 chr3:50004209 C/T cg24110177 chr3:50126178 RBM5 -0.48 -7.62 -0.38 2.55e-13 Intelligence (multi-trait analysis); LIHC cis rs611744 0.647 rs2848620 chr8:109249551 G/T cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs7312933 0.558 rs1796388 chr12:42785987 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.22 -0.41 4.17e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03347828 chr17:7739579 NA 0.45 6.91 0.35 2.37e-11 Cognitive function; LIHC cis rs12594515 1.000 rs8039622 chr15:45986431 A/G cg01629716 chr15:45996671 NA 0.52 9.65 0.46 1.25e-19 Waist circumference;Weight; LIHC cis rs1499614 0.803 rs1796229 chr7:66119661 G/A cg18252515 chr7:66147081 NA -1.34 -18.13 -0.7 5.81e-52 Gout; LIHC cis rs6952808 1.000 rs12699404 chr7:1894022 A/T cg21782813 chr7:2030301 MAD1L1 0.44 7.13 0.36 5.9e-12 Bipolar disorder and schizophrenia; LIHC cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg10802521 chr3:52805072 NEK4 -0.44 -7.22 -0.36 3.41e-12 Bipolar disorder; LIHC cis rs9902453 0.904 rs8071742 chr17:28361669 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs5769765 0.773 rs4075331 chr22:50302850 A/G cg26441486 chr22:50317300 CRELD2 0.35 6.29 0.32 9.96e-10 Schizophrenia; LIHC cis rs2576037 0.623 rs2576040 chr18:44582027 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.62 -9.23 -0.45 2.92e-18 Personality dimensions; LIHC cis rs10779751 1.000 rs4845854 chr1:11261929 T/C cg08854313 chr1:11322531 MTOR 0.81 12.45 0.56 1.35e-29 Body mass index; LIHC cis rs6088590 0.582 rs6059909 chr20:33139691 C/A cg08999081 chr20:33150536 PIGU 0.69 13.72 0.6 1.95e-34 Coronary artery disease; LIHC cis rs2282032 0.550 rs58363992 chr14:90766361 T/C cg04374321 chr14:90722782 PSMC1 0.49 7.07 0.36 8.63e-12 Longevity; LIHC cis rs6879260 1.000 rs7706951 chr5:179733407 C/T cg23248424 chr5:179741104 GFPT2 -0.41 -6.0 -0.31 5.08e-9 Height; LIHC cis rs1008375 1.000 rs10011865 chr4:17645710 G/A cg04450456 chr4:17643702 FAM184B 0.34 5.74 0.3 2.05e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg12310025 chr6:25882481 NA -0.69 -8.56 -0.42 3.78e-16 Intelligence (multi-trait analysis); LIHC cis rs6840360 1.000 rs6810860 chr4:152603164 C/T cg22705602 chr4:152727874 NA 0.29 6.18 0.32 1.8e-9 Intelligence (multi-trait analysis); LIHC cis rs6586163 0.546 rs12359362 chr10:90753145 G/C cg03111039 chr10:90751583 FAS;ACTA2 0.8 12.8 0.57 6.64e-31 Chronic lymphocytic leukemia; LIHC cis rs910316 0.967 rs4903293 chr14:75656568 A/G cg11812906 chr14:75593930 NEK9 -0.69 -13.2 -0.58 1.92e-32 Height; LIHC cis rs60871478 1.000 rs4720930 chr7:808073 G/A cg04727924 chr7:799746 HEATR2 -0.57 -8.5 -0.42 6.08e-16 Cerebrospinal P-tau181p levels; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg11060661 chr22:24314208 DDT;DDTL 0.65 11.07 0.51 1.52e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs208520 0.690 rs3899423 chr6:66835285 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -8.29 -0.41 2.57e-15 Exhaled nitric oxide output; LIHC cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg06634786 chr22:41940651 POLR3H 0.83 8.89 0.43 3.5e-17 Vitiligo; LIHC cis rs5769765 0.955 rs4075330 chr22:50303249 G/A cg26441486 chr22:50317300 CRELD2 0.37 6.35 0.32 6.78e-10 Schizophrenia; LIHC cis rs11951515 0.509 rs12521249 chr5:43558629 T/C cg01983248 chr5:43482804 C5orf28 0.37 6.18 0.32 1.87e-9 Metabolite levels (X-11787); LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg11905131 chr22:24372483 LOC391322 -0.58 -7.84 -0.39 5.71e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7264396 0.528 rs3787174 chr20:34487921 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.57 -7.63 -0.38 2.4e-13 Total cholesterol levels; LIHC cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.47 0.33 3.38e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10242455 0.571 rs56167514 chr7:99161347 A/G cg18809830 chr7:99032528 PTCD1 -0.83 -6.66 -0.34 1.07e-10 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01148728 chr11:117198424 CEP164 0.45 6.52 0.33 2.54e-10 Cognitive function; LIHC cis rs7617773 0.817 rs6806112 chr3:48276077 A/T cg11946769 chr3:48343235 NME6 0.64 8.84 0.43 5.05e-17 Coronary artery disease; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg11905131 chr22:24372483 LOC391322 -0.64 -9.15 -0.44 5.41e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs11088226 1.000 rs2833888 chr21:33927560 A/G cg09050820 chr6:167586206 TCP10L2 0.74 11.45 0.53 6.53e-26 Gastritis; LIHC cis rs7618501 1.000 rs6446295 chr3:49809063 G/T cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.08e-11 Intelligence (multi-trait analysis); LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.48 -6.75 -0.34 6.17e-11 Lymphocyte counts; LIHC cis rs7116495 0.609 rs1791449 chr11:71579662 C/T cg26138937 chr11:71823887 C11orf51 0.7 6.86 0.35 3.27e-11 Severe influenza A (H1N1) infection; LIHC cis rs546131 0.642 rs34191151 chr11:34850509 C/G cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.55 -0.33 2.17e-10 Lung disease severity in cystic fibrosis; LIHC cis rs1712517 0.838 rs1891293 chr10:105001797 C/T cg05636881 chr10:105038444 INA -0.42 -6.72 -0.34 7.63e-11 Migraine; LIHC cis rs11030122 0.702 rs17081 chr11:3987830 A/G cg18678763 chr11:4115507 RRM1 0.58 8.62 0.42 2.55e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs1552244 0.882 rs6443276 chr3:10008905 C/A cg00149659 chr3:10157352 C3orf10 0.49 5.71 0.3 2.4e-8 Alzheimer's disease; LIHC cis rs7144547 0.950 rs8004137 chr14:81884857 A/G cg23690444 chr14:81902736 NA 0.68 9.42 0.45 7.17e-19 Prudent dietary pattern; LIHC cis rs929354 1.000 rs1182452 chr7:157053618 G/A cg17757837 chr7:157058334 UBE3C -0.84 -14.07 -0.61 8.63e-36 Body mass index; LIHC cis rs56146971 0.714 rs55709253 chr14:91853363 T/C cg16433844 chr14:91963127 SMEK1 -0.53 -6.28 -0.32 1.02e-9 Alzheimer disease and age of onset; LIHC trans rs4843747 0.697 rs72818533 chr16:88073841 G/A cg26811252 chr16:29126840 RRN3P2 0.47 7.42 0.37 9.14e-13 Menopause (age at onset); LIHC cis rs2439831 0.867 rs2412778 chr15:43660982 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.86 0.51 8.06e-24 Lung cancer in ever smokers; LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg23131131 chr22:24373011 LOC391322 0.58 8.09 0.4 1.03e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.8 -0.57 6.21e-31 Alzheimer's disease; LIHC cis rs7572733 0.534 rs2574832 chr2:198704818 T/G cg10820045 chr2:198174542 NA 0.47 7.05 0.36 1.01e-11 Dermatomyositis; LIHC cis rs634534 0.562 rs642293 chr11:65730217 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.86 0.3 1.11e-8 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs6500602 0.929 rs9926114 chr16:4478322 C/G cg08645402 chr16:4508243 NA 0.37 6.84 0.35 3.57e-11 Schizophrenia; LIHC cis rs9549328 0.731 rs2873371 chr13:113616242 C/T cg18289306 chr13:113640169 MCF2L 0.42 6.27 0.32 1.12e-9 Systolic blood pressure; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg22963979 chr7:1858916 MAD1L1 -0.44 -6.98 -0.35 1.53e-11 Bipolar disorder and schizophrenia; LIHC cis rs2576037 0.526 rs10853547 chr18:44530548 A/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.07 -0.36 8.75e-12 Personality dimensions; LIHC cis rs8177253 0.965 rs7638018 chr3:133495461 C/T cg12373951 chr3:133503437 NA -0.68 -12.48 -0.56 1.02e-29 Iron status biomarkers; LIHC cis rs9814567 1.000 rs1138273 chr3:134261437 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs5769765 0.908 rs7410318 chr22:50317049 T/C cg26441486 chr22:50317300 CRELD2 0.38 6.46 0.33 3.7e-10 Schizophrenia; LIHC cis rs240764 0.604 rs9404016 chr6:101177728 G/A cg12253828 chr6:101329408 ASCC3 0.44 7.08 0.36 8.31e-12 Neuroticism; LIHC cis rs2204008 0.777 rs11179774 chr12:38219559 A/C cg13010199 chr12:38710504 ALG10B 0.49 5.74 0.3 2.11e-8 Bladder cancer; LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg09455208 chr3:40491958 NA 0.39 8.05 0.4 1.42e-14 Renal cell carcinoma; LIHC cis rs8062405 0.755 rs56272201 chr16:28580685 A/G cg07382826 chr16:28625726 SULT1A1 0.49 7.52 0.38 4.75e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs7395662 0.591 rs4882138 chr11:48619321 A/G cg15704280 chr7:45808275 SEPT13 -0.47 -7.01 -0.35 1.29e-11 HDL cholesterol; LIHC cis rs6545883 0.929 rs10173974 chr2:61748900 C/G cg15711740 chr2:61764176 XPO1 -0.44 -6.24 -0.32 1.26e-9 Tuberculosis; LIHC cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg06481639 chr22:41940642 POLR3H 0.71 7.02 0.35 1.24e-11 Vitiligo; LIHC cis rs35110281 0.811 rs4819264 chr21:45017349 G/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.6 -0.34 1.58e-10 Mean corpuscular volume; LIHC cis rs7000551 0.751 rs2469775 chr8:22373238 T/C cg12081754 chr8:22256438 SLC39A14 0.41 6.4 0.33 5.11e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7587476 0.689 rs78989396 chr2:215714816 C/T cg04004882 chr2:215674386 BARD1 0.56 7.6 0.38 2.86e-13 Neuroblastoma; LIHC cis rs4319547 0.615 rs2341439 chr12:122848096 C/G cg23029597 chr12:123009494 RSRC2 -0.49 -6.98 -0.35 1.58e-11 Body mass index; LIHC cis rs7208859 0.623 rs11657369 chr17:29136468 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg26913058 chr16:419975 MRPL28 -0.52 -7.36 -0.37 1.36e-12 Bone mineral density (spine);Bone mineral density; LIHC cis rs7520050 0.807 rs4274104 chr1:46217941 T/C cg03146154 chr1:46216737 IPP 0.48 8.08 0.4 1.12e-14 Red blood cell count;Reticulocyte count; LIHC cis rs7572733 0.534 rs1401092 chr2:198792320 C/A cg00792783 chr2:198669748 PLCL1 -0.45 -6.66 -0.34 1.09e-10 Dermatomyositis; LIHC cis rs7100689 0.784 rs7895042 chr10:82095276 G/A cg01528321 chr10:82214614 TSPAN14 0.88 12.08 0.55 3.18e-28 Post bronchodilator FEV1; LIHC cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg05564831 chr3:52568323 NT5DC2 0.35 5.71 0.3 2.39e-8 Bipolar disorder; LIHC cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg13047869 chr3:10149882 C3orf24 0.52 5.97 0.31 5.86e-9 Alzheimer's disease; LIHC cis rs9309473 0.851 rs6546850 chr2:73831147 A/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.92 -0.35 2.17e-11 Metabolite levels; LIHC cis rs12497850 1.000 rs12493578 chr3:48730116 C/T cg06212747 chr3:49208901 KLHDC8B -0.5 -6.22 -0.32 1.46e-9 Parkinson's disease; LIHC cis rs11098499 0.691 rs28396837 chr4:120271541 G/A cg09307838 chr4:120376055 NA 0.62 9.83 0.47 3e-20 Corneal astigmatism; LIHC cis rs1577917 0.839 rs1447159 chr6:86609249 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.23 -0.36 3.14e-12 Response to antipsychotic treatment; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg08556938 chr17:58512855 NA 0.43 6.49 0.33 3.05e-10 Electroencephalogram traits; LIHC trans rs116095464 0.558 rs60251075 chr5:245292 T/C cg00938859 chr5:1591904 SDHAP3 0.57 7.07 0.36 8.57e-12 Breast cancer; LIHC cis rs7312933 0.584 rs6582395 chr12:42700141 T/C cg01256987 chr12:42539512 GXYLT1 -0.35 -5.71 -0.3 2.39e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.75 0.8 3.26e-78 Prudent dietary pattern; LIHC cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg11890956 chr21:40555474 PSMG1 -0.5 -8.17 -0.4 5.97e-15 Cognitive function; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg02475777 chr4:1388615 CRIPAK 0.55 8.22 0.41 4.42e-15 Longevity; LIHC cis rs6690583 0.562 rs11588919 chr1:85442813 A/T cg22153463 chr1:85462885 MCOLN2 0.54 6.42 0.33 4.69e-10 Serum sulfate level; LIHC cis rs644799 0.544 rs1727165 chr11:95521648 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.67 11.02 0.51 2.34e-24 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9910055 0.552 rs4793084 chr17:42317371 G/T cg08499158 chr17:42289980 UBTF 0.49 8.29 0.41 2.68e-15 Total body bone mineral density; LIHC cis rs4819052 0.634 rs8128636 chr21:46690633 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.65 0.38 2.11e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg21782813 chr7:2030301 MAD1L1 0.51 8.99 0.44 1.68e-17 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg07677032 chr17:61819896 STRADA 0.41 6.09 0.31 3.04e-9 Prudent dietary pattern; LIHC cis rs10751667 1.000 rs10751667 chr11:941941 A/T cg10932868 chr11:921992 NA 0.35 6.63 0.34 1.3100000000000001e-10 Alzheimer's disease (late onset); LIHC cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg25894440 chr7:65020034 NA -0.55 -6.33 -0.32 7.79e-10 Diabetic kidney disease; LIHC cis rs4906332 0.782 rs2236281 chr14:104000518 G/T cg19000871 chr14:103996768 TRMT61A -0.55 -8.9 -0.43 3.3e-17 Coronary artery disease; LIHC cis rs6062302 0.522 rs6090475 chr20:62245397 C/A cg16989086 chr20:62203971 PRIC285 0.57 8.25 0.41 3.51e-15 Glioblastoma; LIHC cis rs1008375 0.931 rs2098151 chr4:17577490 T/C cg02297831 chr4:17616191 MED28 0.49 7.41 0.37 9.94e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs5769765 0.874 rs11703411 chr22:50258751 G/A cg26441486 chr22:50317300 CRELD2 -0.33 -5.92 -0.31 7.71e-9 Schizophrenia; LIHC cis rs1008375 1.000 rs10939744 chr4:17664473 G/T cg02297831 chr4:17616191 MED28 0.42 6.67 0.34 1.01e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg23758822 chr17:41437982 NA 0.94 18.09 0.7 8.44e-52 Menopause (age at onset); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg01172785 chr16:50092553 NA 0.4 6.46 0.33 3.5e-10 Immature fraction of reticulocytes; LIHC cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg27297192 chr10:134578999 INPP5A 0.53 7.42 0.37 9.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs546131 0.600 rs525202 chr11:34821948 A/C cg11058730 chr11:34937778 PDHX;APIP 0.61 9.05 0.44 1.11e-17 Lung disease severity in cystic fibrosis; LIHC cis rs9457247 0.602 rs2239827 chr6:167490945 G/A cg12798992 chr6:167411361 FGFR1OP 0.49 7.08 0.36 8.35e-12 Crohn's disease; LIHC cis rs1182196 0.502 rs757786 chr7:2836019 C/T cg18446336 chr7:2847575 GNA12 -0.33 -6.6 -0.34 1.52e-10 Plateletcrit; LIHC cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg18279126 chr7:2041391 MAD1L1 0.36 5.73 0.3 2.26e-8 Bipolar disorder and schizophrenia; LIHC cis rs60871478 0.947 rs7790823 chr7:788923 T/G cg13844804 chr7:814759 HEATR2 0.45 5.99 0.31 5.46e-9 Cerebrospinal P-tau181p levels; LIHC cis rs7572733 0.534 rs10931794 chr2:198776140 C/T cg03934865 chr2:198174659 NA -0.46 -6.7 -0.34 8.85e-11 Dermatomyositis; LIHC cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg17971929 chr21:40555470 PSMG1 0.78 8.86 0.43 4.35e-17 Cognitive function; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg11494091 chr17:61959527 GH2 0.45 8.11 0.4 8.96e-15 Prudent dietary pattern; LIHC cis rs7945718 0.621 rs4514397 chr11:12689768 G/T cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs35306767 0.903 rs61830933 chr10:934195 G/A cg26597838 chr10:835615 NA 1.46 16.71 0.67 3.08e-46 Eosinophil percentage of granulocytes; LIHC cis rs9916302 0.904 rs620686 chr17:37453617 A/G cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC cis rs1865721 0.682 rs1561080 chr18:73145847 A/G cg26385618 chr18:73139727 C18orf62 -0.26 -7.26 -0.37 2.56e-12 Intelligence; LIHC cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg08219700 chr8:58056026 NA 0.52 6.92 0.35 2.19e-11 Developmental language disorder (linguistic errors); LIHC cis rs801193 1.000 rs2659906 chr7:66165310 T/C cg14393609 chr7:65229607 NA 0.38 5.91 0.3 8.22e-9 Aortic root size; LIHC cis rs7131987 0.650 rs10843382 chr12:29451721 G/A cg16970926 chr12:29381810 FAR2 0.27 5.75 0.3 1.94e-8 QT interval; LIHC cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg04944784 chr2:26401820 FAM59B -0.66 -8.73 -0.43 1.12e-16 Gut microbiome composition (summer); LIHC cis rs9596863 1.000 rs9596856 chr13:54409401 C/T ch.13.53330881F chr13:54432880 NA 0.44 5.98 0.31 5.48e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs16854884 0.657 rs35067746 chr3:143747147 T/A cg06585982 chr3:143692056 C3orf58 0.55 7.21 0.36 3.58e-12 Economic and political preferences (feminism/equality); LIHC trans rs745109 0.816 rs74443614 chr2:86845509 G/C cg24539459 chr1:146658275 FMO5 -0.61 -6.39 -0.33 5.4e-10 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; LIHC cis rs1129187 0.748 rs6458312 chr6:42904274 G/T cg13397359 chr6:42928475 GNMT 0.46 6.44 0.33 3.96e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs34172651 0.517 rs200528 chr16:24759131 A/G cg04756594 chr16:24857601 SLC5A11 -0.6 -9.17 -0.44 4.61e-18 Intelligence (multi-trait analysis); LIHC cis rs1775715 0.811 rs1775741 chr10:32267284 C/T cg14930904 chr10:32216787 ARHGAP12 -0.39 -6.97 -0.35 1.67e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs2976388 1.000 rs1045547 chr8:143763757 T/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg02475777 chr4:1388615 CRIPAK 0.55 8.35 0.41 1.67e-15 Longevity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05301818 chr8:125385252 TMEM65 0.48 6.47 0.33 3.47e-10 Lung function (FEV1/FVC); LIHC cis rs7584330 0.657 rs7599658 chr2:238352898 A/C cg14458575 chr2:238380390 NA -0.41 -6.16 -0.32 2.01e-9 Prostate cancer; LIHC cis rs600806 0.778 rs12145677 chr1:110023610 G/A cg08911820 chr1:110026001 ATXN7L2 0.52 6.35 0.32 6.71e-10 Intelligence (multi-trait analysis); LIHC cis rs9322817 0.583 rs6941988 chr6:105146656 C/T cg02098413 chr6:105308735 HACE1 0.4 8.09 0.4 1.06e-14 Thyroid stimulating hormone; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg00280220 chr17:61926910 NA 0.43 6.81 0.35 4.41e-11 Prudent dietary pattern; LIHC cis rs7937682 1.000 rs7937682 chr11:111579939 C/G cg09085632 chr11:111637200 PPP2R1B -1.06 -14.91 -0.63 4.45e-39 Primary sclerosing cholangitis; LIHC trans rs1005277 0.579 rs2505240 chr10:38442419 G/T cg17830980 chr10:43048298 ZNF37B -0.56 -11.46 -0.53 6.04e-26 Extrinsic epigenetic age acceleration; LIHC cis rs6691722 0.583 rs7537875 chr1:24695151 A/T cg18323236 chr1:24743029 NIPAL3 0.32 6.02 0.31 4.45e-9 Response to interferon beta in multiple sclerosis; LIHC cis rs151997 0.629 rs152808 chr5:50207382 G/C cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC cis rs11098499 0.866 rs12510451 chr4:120289143 C/T cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs2235642 0.785 rs1057983 chr16:1660274 A/G cg09025071 chr16:1593152 IFT140;TMEM204 0.3 6.04 0.31 4.11e-9 Coronary artery disease; LIHC cis rs4808199 0.894 rs9304960 chr19:19465529 G/A cg03709012 chr19:19516395 GATAD2A 0.99 15.84 0.65 9.42e-43 Nonalcoholic fatty liver disease; LIHC cis rs1552244 0.554 rs2272120 chr3:10046703 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC cis rs1670533 1.000 rs6852155 chr4:1067638 T/G cg20887711 chr4:1340912 KIAA1530 0.48 6.03 0.31 4.23e-9 Recombination rate (females); LIHC cis rs2479724 0.905 rs2149274 chr6:41839092 T/C cg17623882 chr6:41773611 USP49 -0.56 -8.79 -0.43 7.45e-17 Menarche (age at onset); LIHC cis rs929354 0.772 rs2023975 chr7:157012096 G/A cg16102536 chr7:156981717 UBE3C 0.37 6.16 0.32 2.02e-9 Body mass index; LIHC trans rs35110281 0.782 rs2329442 chr21:45041790 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.21e-9 Mean corpuscular volume; LIHC cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg07308232 chr7:1071921 C7orf50 -0.56 -9.1 -0.44 7.76e-18 Longevity;Endometriosis; LIHC cis rs8044995 0.563 rs73613962 chr16:68361974 T/G cg05110241 chr16:68378359 PRMT7 -0.9 -10.13 -0.48 2.79e-21 Schizophrenia; LIHC cis rs7833986 0.534 rs72653928 chr8:56907735 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.8 8.18 0.4 5.71e-15 Height; LIHC cis rs910316 0.692 rs7156586 chr14:75506230 A/T cg11812906 chr14:75593930 NEK9 0.49 8.75 0.43 1.02e-16 Height; LIHC cis rs67460515 0.563 rs11922959 chr3:160828871 A/G cg17135325 chr3:160939158 NMD3 0.55 7.82 0.39 6.82e-14 Parkinson's disease; LIHC cis rs4718428 0.705 rs13220977 chr7:66337648 A/T cg12165864 chr7:66369176 NA 0.48 6.92 0.35 2.27e-11 Corneal structure; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs12142240 0.698 rs7525309 chr1:46809025 G/T cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC trans rs11098499 0.743 rs10003567 chr4:120241674 C/T cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs8180040 0.701 rs1079276 chr3:47045739 C/G cg27129171 chr3:47204927 SETD2 0.66 11.7 0.53 7.97e-27 Colorectal cancer; LIHC cis rs1008375 0.932 rs13109475 chr4:17677565 C/G cg16339924 chr4:17578868 LAP3 -0.47 -6.26 -0.32 1.14e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7520050 0.933 rs6694340 chr1:46289416 C/T cg03146154 chr1:46216737 IPP -0.37 -5.98 -0.31 5.62e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10089 0.953 rs3805615 chr5:127519049 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.5 6.17 0.32 1.92e-9 Ileal carcinoids; LIHC cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg06634786 chr22:41940651 POLR3H -0.77 -7.75 -0.39 1.09e-13 Vitiligo; LIHC cis rs780096 0.546 rs715326 chr2:27725761 A/G cg21747090 chr2:27597821 SNX17 0.42 6.37 0.33 6.06e-10 Total body bone mineral density; LIHC cis rs80282103 0.717 rs41299206 chr10:1120236 T/C cg18964960 chr10:1102726 WDR37 0.69 6.33 0.32 7.61e-10 Glomerular filtration rate (creatinine); LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg04013166 chr16:89971882 TCF25 0.59 7.58 0.38 3.25e-13 Skin colour saturation; LIHC cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg11644478 chr21:40555479 PSMG1 0.44 6.98 0.35 1.51e-11 Cognitive function; LIHC cis rs2073499 1.000 rs10510755 chr3:50281168 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 0.73 7.66 0.38 1.93e-13 Schizophrenia; LIHC cis rs611744 0.647 rs2848620 chr8:109249551 G/T cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg18225595 chr11:63971243 STIP1 0.61 7.88 0.39 4.42e-14 Mean platelet volume; LIHC cis rs6424115 0.793 rs2502998 chr1:24198327 T/A cg04160030 chr1:24195659 FUCA1 -0.36 -5.88 -0.3 9.82e-9 Immature fraction of reticulocytes; LIHC cis rs6088590 0.648 rs6059991 chr20:33280836 C/T cg06115741 chr20:33292138 TP53INP2 0.39 5.74 0.3 2.05e-8 Coronary artery disease; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg22903471 chr2:27725779 GCKR -0.48 -8.39 -0.41 1.28e-15 Total body bone mineral density; LIHC cis rs9457247 1.000 rs421214 chr6:167396629 A/G cg12798992 chr6:167411361 FGFR1OP 0.59 9.84 0.47 2.7e-20 Crohn's disease; LIHC cis rs7589728 0.514 rs74426843 chr2:88459388 C/T cg14558114 chr2:88469736 THNSL2 0.59 5.72 0.3 2.3e-8 Plasma clusterin levels; LIHC cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg26818010 chr10:134567672 INPP5A -0.66 -8.72 -0.43 1.21e-16 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1882538 0.596 rs10281827 chr7:133081810 A/G cg10665199 chr7:133106180 EXOC4 0.51 8.47 0.42 7.41e-16 Intelligence (multi-trait analysis); LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg05484376 chr2:27715224 FNDC4 0.34 5.74 0.3 2.12e-8 Total body bone mineral density; LIHC cis rs13108904 0.539 rs11247997 chr4:1361057 T/C cg22903657 chr4:1355424 KIAA1530 -0.46 -6.5 -0.33 2.84e-10 Obesity-related traits; LIHC cis rs11628318 0.614 rs7155489 chr14:103123119 C/T cg12046867 chr14:103022105 NA 0.49 6.87 0.35 2.96e-11 Platelet count; LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.41 -0.33 4.74e-10 Total body bone mineral density; LIHC cis rs68170813 0.559 rs2023892 chr7:106847686 C/T cg02696742 chr7:106810147 HBP1 0.5 5.73 0.3 2.21e-8 Coronary artery disease; LIHC cis rs17685 0.753 rs11764129 chr7:75761890 T/C cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1023500 0.573 rs2413666 chr22:42459622 C/T cg04733989 chr22:42467013 NAGA 0.66 9.48 0.46 4.36e-19 Schizophrenia; LIHC cis rs1707322 0.827 rs10890347 chr1:46242332 A/T cg06784218 chr1:46089804 CCDC17 -0.4 -6.54 -0.33 2.22e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg09455208 chr3:40491958 NA 0.4 8.1 0.4 9.64e-15 Renal cell carcinoma; LIHC cis rs2439831 1.000 rs689754 chr15:43775895 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.73 0.43 1.13e-16 Lung cancer in ever smokers; LIHC cis rs2841277 0.770 rs10149193 chr14:105403474 C/T cg21017887 chr14:105400489 NA 0.66 12.71 0.57 1.42e-30 Rheumatoid arthritis; LIHC cis rs74233809 1.000 rs11191514 chr10:104773364 C/T cg03493300 chr10:104813866 CNNM2 0.45 6.06 0.31 3.62e-9 Birth weight; LIHC cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -13.16 -0.58 2.85e-32 Alzheimer's disease; LIHC cis rs854572 0.600 rs705382 chr7:94955221 C/G cg07404485 chr7:94953653 PON1 -0.37 -6.29 -0.32 9.56e-10 Paraoxonase activity; LIHC cis rs1538970 0.884 rs1771551 chr1:45883643 C/G cg05343316 chr1:45956843 TESK2 0.51 7.52 0.38 4.89e-13 Platelet count; LIHC cis rs9308433 0.529 rs3767842 chr1:214498306 C/T cg06198575 chr1:214491504 SMYD2 0.55 5.82 0.3 1.32e-8 IgG glycosylation; LIHC trans rs1814175 0.817 rs1818890 chr11:49856882 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.7 -0.79 3.61e-74 Height; LIHC cis rs9534288 0.699 rs7139571 chr13:46662584 G/A cg15192986 chr13:46630673 CPB2 -0.43 -6.13 -0.31 2.41e-9 Blood protein levels; LIHC cis rs9916302 0.904 rs11078915 chr17:37715426 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.31 -0.58 7.63e-33 Glomerular filtration rate (creatinine); LIHC cis rs7208859 0.623 rs1061343 chr17:29114276 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9303401 0.625 rs10515159 chr17:56802693 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs1865760 0.963 rs3846838 chr6:25911775 T/C cg03517284 chr6:25882590 NA -0.38 -5.72 -0.3 2.27e-8 Height; LIHC cis rs3820500 0.543 rs7514323 chr1:118002719 A/G cg20383390 chr1:117909022 MAN1A2 0.46 6.02 0.31 4.4e-9 Pneumonia; LIHC cis rs712039 0.652 rs11656503 chr17:35772021 G/T cg16670864 chr17:35848621 DUSP14 0.34 5.76 0.3 1.9e-8 Tuberculosis; LIHC cis rs11663156 1.000 rs2339639 chr18:50928022 A/T cg24270629 chr18:50823537 DCC -0.47 -6.42 -0.33 4.61e-10 Intelligence (multi-trait analysis); LIHC cis rs6840360 0.571 rs11939356 chr4:152505234 G/C cg22705602 chr4:152727874 NA -0.32 -6.22 -0.32 1.42e-9 Intelligence (multi-trait analysis); LIHC cis rs600806 0.850 rs7518013 chr1:109944078 C/T cg08911820 chr1:110026001 ATXN7L2 0.6 7.38 0.37 1.23e-12 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.580 rs11174421 chr12:38105138 A/G cg26384229 chr12:38710491 ALG10B 0.77 9.12 0.44 6.79e-18 Bladder cancer; LIHC trans rs2235573 0.527 rs139887 chr22:38371396 G/C cg19894588 chr14:64061835 NA 0.49 6.59 0.34 1.69e-10 Glioblastoma;Glioma; LIHC cis rs7264396 0.635 rs6060682 chr20:34506331 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -10.59 -0.5 7.71e-23 Total cholesterol levels; LIHC cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg11987759 chr7:65425863 GUSB 0.38 6.06 0.31 3.61e-9 Calcium levels; LIHC cis rs4819052 0.765 rs2838827 chr21:46656146 C/T cg22633049 chr21:46681294 NA -0.35 -5.77 -0.3 1.81e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs796364 1.000 rs281794 chr2:200846666 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.11 0.4 9.34e-15 Schizophrenia; LIHC cis rs6500602 0.702 rs2304634 chr16:4500544 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 6.13 0.31 2.43e-9 Schizophrenia; LIHC trans rs2243480 1.000 rs387676 chr7:65598220 C/T cg10756647 chr7:56101905 PSPH 1.09 13.31 0.58 7.32e-33 Diabetic kidney disease; LIHC cis rs2072499 0.966 rs2842869 chr1:156160696 A/G cg24450063 chr1:156163899 SLC25A44 1.07 18.56 0.71 1.07e-53 Testicular germ cell tumor; LIHC cis rs7618501 0.602 rs10049087 chr3:50123417 A/G cg21467203 chr3:49911342 NA 0.43 7.54 0.38 4.31e-13 Intelligence (multi-trait analysis); LIHC cis rs9911578 0.867 rs72628394 chr17:57121313 C/T cg12560992 chr17:57184187 TRIM37 -0.94 -16.87 -0.67 6.63e-47 Intelligence (multi-trait analysis); LIHC cis rs2439831 0.717 rs690170 chr15:43810422 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.6 7.01 0.35 1.31e-11 Lung cancer in ever smokers; LIHC cis rs2040771 0.872 rs12485084 chr22:19162326 A/G cg02655711 chr22:19163373 SLC25A1 0.33 5.8 0.3 1.53e-8 Metabolite levels (small molecules and protein measures); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13713052 chr3:122102218 FAM162A;CCDC58 0.55 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs611744 0.647 rs13280487 chr8:109270263 G/C cg21045802 chr8:109455806 TTC35 0.58 10.25 0.48 1.1e-21 Dupuytren's disease; LIHC cis rs2282802 0.685 rs7730245 chr5:139628163 C/A cg26211634 chr5:139558579 C5orf32 0.39 6.14 0.32 2.27e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg07133347 chr1:107600762 PRMT6 0.46 6.83 0.35 3.87e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9303401 0.538 rs8078280 chr17:56473132 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.84 11.21 0.52 4.73e-25 Cognitive test performance; LIHC cis rs7131987 0.650 rs12366527 chr12:29474256 C/G cg16970926 chr12:29381810 FAR2 0.28 5.97 0.31 6.02e-9 QT interval; LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg19635926 chr16:89946313 TCF25 0.5 7.04 0.36 1.04e-11 Interleukin-17 levels; LIHC cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg09323728 chr8:95962352 TP53INP1 -0.3 -6.51 -0.33 2.68e-10 Type 2 diabetes; LIHC cis rs3106136 0.967 rs282449 chr4:95141228 G/A cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.18 -0.4 5.45e-15 Capecitabine sensitivity; LIHC cis rs10504073 0.584 rs74457150 chr8:49890753 C/G cg00325661 chr8:49890786 NA 0.38 9.1 0.44 7.47e-18 Blood metabolite ratios; LIHC cis rs2295359 1.000 rs10889664 chr1:67635475 C/T cg12940439 chr1:67600707 NA 0.37 6.48 0.33 3.16e-10 Psoriasis; LIHC trans rs7395662 0.517 rs11039885 chr11:48647107 A/G cg15704280 chr7:45808275 SEPT13 -0.48 -7.25 -0.36 2.84e-12 HDL cholesterol; LIHC cis rs9788682 0.947 rs12439240 chr15:78829091 T/C cg06917634 chr15:78832804 PSMA4 -0.54 -7.7 -0.38 1.48e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs7582720 1.000 rs72936869 chr2:203788950 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs738322 0.870 rs5750558 chr22:38582497 G/A cg25457927 chr22:38595422 NA 0.29 7.2 0.36 3.93e-12 Cutaneous nevi; LIHC cis rs7089973 0.584 rs758585 chr10:116582560 C/A cg23260525 chr10:116636907 FAM160B1 0.39 7.71 0.38 1.42e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs752010 0.655 rs10890145 chr1:42086290 A/G cg06885757 chr1:42089581 HIVEP3 0.31 6.52 0.33 2.59e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs116248771 0.739 rs16829290 chr3:158392278 T/C cg16708174 chr3:158430962 RARRES1 0.49 6.53 0.33 2.32e-10 diarrhoeal disease at age 2; LIHC cis rs7107174 0.901 rs10899493 chr11:78117534 T/C cg02023728 chr11:77925099 USP35 0.35 6.55 0.33 2.07e-10 Testicular germ cell tumor; LIHC cis rs7552404 1.000 rs211723 chr1:76103030 C/T cg22875332 chr1:76189707 ACADM -0.47 -6.92 -0.35 2.27e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs16958440 0.867 rs12326221 chr18:44682893 G/T cg17192377 chr18:44677553 HDHD2 0.9 8.34 0.41 1.78e-15 Sitting height ratio; LIHC cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.55 6.41 0.33 4.71e-10 Cerebrospinal P-tau181p levels; LIHC cis rs7264396 0.790 rs2425096 chr20:34308588 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.89 -0.54 1.66e-27 Total cholesterol levels; LIHC cis rs7246657 0.943 rs34603719 chr19:37794528 T/G cg23950597 chr19:37808831 NA -0.52 -6.56 -0.33 2.03e-10 Coronary artery calcification; LIHC cis rs6964587 1.000 rs13231238 chr7:91653851 T/G cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs9640161 0.789 rs1464751 chr7:150021282 C/T cg17279839 chr7:150038598 RARRES2 0.51 10.65 0.5 4.77e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs1371867 0.846 rs959022 chr8:101295992 T/A cg06636551 chr8:101224915 SPAG1 -0.5 -9.06 -0.44 1.02e-17 Atrioventricular conduction; LIHC cis rs807669 0.903 rs1771540 chr22:19173933 T/A cg02655711 chr22:19163373 SLC25A1 0.73 11.2 0.52 5.32e-25 Metabolite levels; LIHC cis rs7312933 0.510 rs1907705 chr12:42451122 T/A cg17420585 chr12:42539391 GXYLT1 -0.56 -9.66 -0.46 1.12e-19 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1506636 0.889 rs619075 chr7:123426317 A/T cg03229431 chr7:123269106 ASB15 0.6 11.91 0.54 1.36e-27 Plateletcrit;Platelet count; LIHC cis rs939574 0.790 rs2385397 chr2:220087796 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.86 -6.4 -0.33 5.02e-10 Platelet distribution width; LIHC cis rs9910055 0.509 rs9916444 chr17:42313512 C/G cg09913183 chr17:42254507 C17orf65;ASB16 0.66 9.66 0.46 1.15e-19 Total body bone mineral density; LIHC cis rs12744310 1.000 rs12031417 chr1:41763028 A/G cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg04944784 chr2:26401820 FAM59B 0.71 9.07 0.44 9.29e-18 Gut microbiome composition (summer); LIHC cis rs853679 0.517 rs9468286 chr6:28079428 C/T cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.53 -7.5 -0.38 5.62e-13 Lymphocyte counts; LIHC cis rs6604026 0.740 rs10874747 chr1:93352491 A/G cg17283838 chr1:93427260 FAM69A -0.42 -5.8 -0.3 1.48e-8 Multiple sclerosis; LIHC cis rs763121 0.819 rs5750629 chr22:38985065 T/C cg21395723 chr22:39101663 GTPBP1 0.41 7.06 0.36 9.58e-12 Menopause (age at onset); LIHC cis rs9911578 0.867 rs4793941 chr17:56472366 G/A cg05425664 chr17:57184151 TRIM37 0.57 8.29 0.41 2.61e-15 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs28480159 chr4:17685707 A/C cg02297831 chr4:17616191 MED28 0.43 6.8 0.35 4.6e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2842992 0.915 rs2842958 chr6:160108425 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.76 0.43 9.46e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs6665290 0.904 rs2297418 chr1:227192579 A/C cg10327440 chr1:227177885 CDC42BPA -1.18 -25.62 -0.81 1.41e-81 Myeloid white cell count; LIHC trans rs1814175 0.645 rs1721996 chr11:49915527 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC trans rs8073060 0.544 rs7211724 chr17:33993414 C/G cg19694781 chr19:47549865 TMEM160 -1.27 -13.88 -0.6 4.83e-35 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9814567 1.000 rs13089966 chr3:134279197 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9918079 0.580 rs13120905 chr4:15612288 A/T cg16509355 chr4:15471240 CC2D2A 0.46 7.1 0.36 7.27e-12 Obesity-related traits; LIHC cis rs9479482 1.000 rs5017316 chr6:150333489 A/T cg25797454 chr6:150327115 RAET1K 0.33 5.98 0.31 5.61e-9 Alopecia areata; LIHC cis rs3770081 1.000 rs3770087 chr2:86267068 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.39 5.72 0.3 2.29e-8 Facial emotion recognition (sad faces); LIHC cis rs10174077 0.874 rs4664490 chr2:152471923 C/G cg19508488 chr2:152266495 RIF1 -0.49 -7.21 -0.36 3.59e-12 Squamous cell lung carcinoma; LIHC cis rs10870270 1.000 rs10870271 chr10:133754807 A/G cg08754478 chr10:133766260 PPP2R2D 0.57 8.5 0.42 6.04e-16 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs11122272 0.735 rs2486737 chr1:231520523 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg02290350 chr8:58132656 NA 0.47 8.61 0.42 2.69e-16 Developmental language disorder (linguistic errors); LIHC cis rs56235845 0.694 rs11749830 chr5:176766547 G/A cg16006841 chr5:176797999 RGS14 0.58 7.92 0.39 3.33e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg15320075 chr8:145703422 NA 0.62 11.64 0.53 1.29e-26 Age at first birth; LIHC cis rs3823572 0.542 rs10269665 chr7:133630418 A/G cg03336402 chr7:133662267 EXOC4 0.46 5.77 0.3 1.81e-8 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs4698635 chr4:17630242 C/A cg16339924 chr4:17578868 LAP3 0.44 6.22 0.32 1.48e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2243480 1.000 rs1553174 chr7:65731194 T/C cg10756647 chr7:56101905 PSPH -1.03 -12.48 -0.56 1.05e-29 Diabetic kidney disease; LIHC cis rs34375054 0.573 rs35698828 chr12:125658603 C/T cg25124228 chr12:125621409 AACS -0.43 -6.61 -0.34 1.47e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs4819052 0.851 rs1056101 chr21:46678702 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 10.81 0.5 1.24e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3784262 0.869 rs12903792 chr15:58261280 C/T cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.42 -0.33 4.59e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs3741404 0.665 rs594461 chr11:63872543 A/G cg05016508 chr11:63871570 FLRT1;MACROD1 0.42 6.68 0.34 9.97e-11 Platelet count; LIHC cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs34779708 0.897 rs12764820 chr10:35386321 G/A cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs875971 0.928 rs6970357 chr7:65968878 T/C cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.09e-10 Aortic root size; LIHC cis rs3099143 1.000 rs3106380 chr15:77104377 G/A cg21673338 chr15:77095150 SCAPER -0.51 -7.64 -0.38 2.21e-13 Recalcitrant atopic dermatitis; LIHC trans rs3780486 0.846 rs10813948 chr9:33121570 G/A cg04842962 chr6:43655489 MRPS18A 1.07 24.52 0.8 2.44e-77 IgG glycosylation; LIHC cis rs1801251 1.000 rs13035829 chr2:233604487 A/T cg25237894 chr2:233734115 C2orf82 0.57 11.03 0.51 2.04e-24 Coronary artery disease; LIHC cis rs8067354 0.645 rs7215180 chr17:57822354 A/G cg02344993 chr17:57696989 CLTC 0.7 11.89 0.54 1.66e-27 Hemoglobin concentration; LIHC cis rs208515 0.525 rs10944871 chr6:66690306 A/G cg07460842 chr6:66804631 NA 0.79 8.97 0.44 1.94e-17 Exhaled nitric oxide levels; LIHC cis rs8141529 0.748 rs1318026 chr22:29283518 A/G cg15103426 chr22:29168792 CCDC117 0.57 9.3 0.45 1.74e-18 Lymphocyte counts; LIHC cis rs77106637 0.585 rs67260737 chr11:72458196 A/G cg03713592 chr11:72463424 ARAP1 0.6 6.61 0.34 1.44e-10 Type 2 diabetes; LIHC cis rs2295359 0.892 rs12401432 chr1:67656931 C/G cg12940439 chr1:67600707 NA 0.35 6.07 0.31 3.37e-9 Psoriasis; LIHC cis rs10089 0.953 rs758179 chr5:127354424 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.28 0.32 1.04e-9 Ileal carcinoids; LIHC cis rs10504229 0.610 rs6987118 chr8:58147851 G/T cg20607798 chr8:58055168 NA 0.52 6.56 0.33 1.98e-10 Developmental language disorder (linguistic errors); LIHC cis rs7945718 0.839 rs11022511 chr11:12834638 A/T cg25843174 chr11:12811716 TEAD1 0.36 8.28 0.41 2.72e-15 Educational attainment (years of education); LIHC cis rs943466 1.000 rs11754690 chr6:33744157 G/A cg25922239 chr6:33757077 LEMD2 -0.47 -5.77 -0.3 1.75e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg08888203 chr3:10149979 C3orf24 0.57 6.81 0.35 4.35e-11 Alzheimer's disease; LIHC cis rs17376456 0.825 rs6898842 chr5:93213221 T/C cg25358565 chr5:93447407 FAM172A 1.06 9.55 0.46 2.59e-19 Diabetic retinopathy; LIHC cis rs35955747 0.871 rs2013254 chr22:31690803 G/A cg22777020 chr22:31556080 RNF185 -0.49 -5.76 -0.3 1.91e-8 Neutrophil count;Sum basophil neutrophil counts; LIHC cis rs546131 0.642 rs579926 chr11:34853155 C/T cg11058730 chr11:34937778 PDHX;APIP 0.64 9.41 0.45 7.21e-19 Lung disease severity in cystic fibrosis; LIHC cis rs12477438 0.501 rs2516833 chr2:99777405 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs1858740 0.509 rs196375 chr3:38422919 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.73 11.24 0.52 3.73e-25 Schizophrenia; LIHC cis rs875971 0.862 rs1167390 chr7:65575893 G/A cg11764359 chr7:65958608 NA -0.82 -13.6 -0.59 5.83e-34 Aortic root size; LIHC cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg25894440 chr7:65020034 NA -0.54 -6.13 -0.31 2.37e-9 Diabetic kidney disease; LIHC cis rs644799 0.526 rs542509 chr11:95641602 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.59 8.27 0.41 2.93e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4819052 0.851 rs1006779 chr21:46670752 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.66 10.23 0.48 1.27e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs60871478 0.578 rs62432900 chr7:826794 G/C cg27478167 chr7:817139 HEATR2 -0.51 -6.82 -0.35 4.1e-11 Cerebrospinal P-tau181p levels; LIHC cis rs7208859 0.623 rs7208441 chr17:29143863 C/T cg13385521 chr17:29058706 SUZ12P 0.84 8.25 0.41 3.5e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8180040 0.726 rs2305638 chr3:47046842 G/C cg27129171 chr3:47204927 SETD2 0.66 11.57 0.53 2.41e-26 Colorectal cancer; LIHC cis rs116095464 0.558 rs7356535 chr5:284117 G/T cg22496380 chr5:211416 CCDC127 -1.1 -10.33 -0.49 5.84e-22 Breast cancer; LIHC cis rs7847628 0.765 rs7026635 chr9:123550027 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.51 -7.09 -0.36 7.82e-12 Birth weight; LIHC cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg20090690 chr10:134436459 INPP5A 0.44 6.02 0.31 4.42e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs79149102 0.579 rs8033125 chr15:75374970 G/C cg09165964 chr15:75287851 SCAMP5 -0.54 -7.16 -0.36 5.11e-12 Lung cancer; LIHC cis rs2224391 1.000 rs9504369 chr6:5261575 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.41 -6.24 -0.32 1.32e-9 Height; LIHC cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Bipolar disorder; LIHC cis rs7264396 0.790 rs2425115 chr20:34322418 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.78 -0.54 4.13e-27 Total cholesterol levels; LIHC cis rs9303401 0.659 rs11079358 chr17:56920949 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.6 0.56 3.51e-30 Cognitive test performance; LIHC cis rs1577917 0.740 rs7752502 chr6:86410651 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.48 0.33 3.15e-10 Response to antipsychotic treatment; LIHC cis rs11031096 0.587 rs2920145 chr11:4070552 G/T cg18678763 chr11:4115507 RRM1 0.45 6.69 0.34 9.2e-11 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6500602 0.893 rs8061742 chr16:4489436 T/C cg08645402 chr16:4508243 NA 0.37 6.78 0.34 5.14e-11 Schizophrenia; LIHC trans rs2243480 1.000 rs13310597 chr7:65598540 A/G cg10756647 chr7:56101905 PSPH 1.1 13.27 0.58 1.02e-32 Diabetic kidney disease; LIHC cis rs2191566 0.960 rs7255315 chr19:44510933 A/T cg20607764 chr19:44506953 ZNF230 -0.41 -6.66 -0.34 1.1e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs3020736 0.500 rs6002614 chr22:42501802 G/A cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC trans rs17253792 0.915 rs76952651 chr14:56188994 G/A cg26951091 chr14:76844913 ESRRB 0.59 6.48 0.33 3.28e-10 Putamen volume; LIHC cis rs1568889 0.838 rs1483858 chr11:28189639 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.19 0.61 3.05e-36 Bipolar disorder; LIHC cis rs7772486 0.790 rs2265469 chr6:146219049 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.84 0.3 1.23e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9818758 0.607 rs67060340 chr3:48915321 C/T cg00383909 chr3:49044727 WDR6 0.96 7.95 0.4 2.65e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs1493916 0.870 rs8083723 chr18:31384398 C/T cg27147174 chr7:100797783 AP1S1 -0.52 -7.1 -0.36 7.3e-12 Life satisfaction; LIHC cis rs172166 0.694 rs9295760 chr6:28147385 G/A cg25329415 chr6:28076851 NA 0.27 5.74 0.3 2.13e-8 Cardiac Troponin-T levels; LIHC cis rs67460515 0.892 rs1478566 chr3:161030335 A/T cg17135325 chr3:160939158 NMD3 0.56 8.07 0.4 1.22e-14 Parkinson's disease; LIHC cis rs3815700 1.000 rs10406750 chr19:33097144 C/T cg02997394 chr19:33096574 ANKRD27 0.73 9.55 0.46 2.58e-19 Eosinophilic esophagitis; LIHC cis rs9733 0.526 rs11204698 chr1:150659545 G/A cg17724175 chr1:150552817 MCL1 0.49 9.85 0.47 2.67e-20 Tonsillectomy; LIHC cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg04944784 chr2:26401820 FAM59B -0.71 -9.3 -0.45 1.7e-18 Gut microbiome composition (summer); LIHC cis rs7408868 0.764 rs62113791 chr19:15277009 C/T cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.68e-8 Pulse pressure; LIHC cis rs8062405 1.000 rs62036620 chr16:28833097 A/G cg07451762 chr16:28383216 NA 0.32 6.14 0.31 2.33e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.6e-18 Bipolar disorder; LIHC cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs7210488 chr17:37539819 T/G cg03013999 chr17:37608204 MED1 -0.36 -5.97 -0.31 5.89e-9 Glomerular filtration rate (creatinine); LIHC cis rs12478296 0.786 rs6721704 chr2:242994923 A/G cg06360820 chr2:242988706 NA -0.85 -13.22 -0.58 1.67e-32 Obesity-related traits; LIHC cis rs10752881 1.000 rs4233193 chr1:182970865 C/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.41 0.49 3.12e-22 Colorectal cancer; LIHC cis rs8180040 1.000 rs1024037 chr3:47318449 C/A cg16586182 chr3:47516702 SCAP 0.57 10.4 0.49 3.34e-22 Colorectal cancer; LIHC cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg24101359 chr6:42928495 GNMT 0.43 5.91 0.3 8.14e-9 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs804280 0.509 rs12719915 chr8:11786255 A/G cg09094615 chr8:17779997 PCM1 0.42 6.14 0.32 2.31e-9 Myopia (pathological); LIHC cis rs35110281 0.667 rs4819285 chr21:45118970 C/T cg04455712 chr21:45112962 RRP1B -0.47 -8.19 -0.4 5.33e-15 Mean corpuscular volume; LIHC cis rs910316 0.967 rs11159121 chr14:75666029 A/T cg08847533 chr14:75593920 NEK9 -0.78 -15.64 -0.65 5.53e-42 Height; LIHC trans rs7618501 0.633 rs9861216 chr3:50059339 A/G cg21659725 chr3:3221576 CRBN -0.66 -10.77 -0.5 1.79e-23 Intelligence (multi-trait analysis); LIHC cis rs332507 0.601 rs11707114 chr3:124375799 C/T cg05980111 chr3:124395277 KALRN 0.32 6.21 0.32 1.57e-9 Plateletcrit; LIHC cis rs12478296 0.818 rs57194240 chr2:243011545 A/G cg18898632 chr2:242989856 NA -0.47 -6.52 -0.33 2.58e-10 Obesity-related traits; LIHC cis rs1707322 1.000 rs11211217 chr1:46348229 C/G cg06784218 chr1:46089804 CCDC17 0.35 6.2 0.32 1.6e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11112613 0.713 rs12296355 chr12:105953321 C/A cg03607813 chr12:105948248 NA 0.63 12.49 0.56 9.39e-30 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs66887589 0.934 rs12648182 chr4:120503891 T/A cg25214090 chr10:38739885 LOC399744 -0.4 -6.41 -0.33 4.85e-10 Diastolic blood pressure; LIHC cis rs9473924 1.000 rs9473924 chr6:50834157 A/C cg14470998 chr6:50812995 TFAP2B -0.41 -6.32 -0.32 8.34e-10 Body mass index; LIHC cis rs1023500 0.505 rs134885 chr22:42673811 C/G cg15557168 chr22:42548783 NA -0.35 -6.06 -0.31 3.55e-9 Schizophrenia; LIHC cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg04944784 chr2:26401820 FAM59B -0.71 -9.0 -0.44 1.63e-17 Gut microbiome composition (summer); LIHC cis rs4474465 0.920 rs10793321 chr11:78237566 A/G cg02023728 chr11:77925099 USP35 -0.36 -6.37 -0.33 6.12e-10 Alzheimer's disease (survival time); LIHC cis rs2279817 0.863 rs2354291 chr1:18027554 G/T cg21791023 chr1:18019539 ARHGEF10L -0.42 -6.52 -0.33 2.58e-10 Neuroticism; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC cis rs1707322 0.721 rs10789471 chr1:46215619 G/A cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs787274 0.718 rs4979170 chr9:115626918 C/G cg13803584 chr9:115635662 SNX30 0.58 6.83 0.35 3.99e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs250677 0.687 rs250664 chr5:148453823 C/T cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -10.09 -0.48 3.92e-21 Platelet count; LIHC cis rs3112357 0.901 rs13307412 chr7:135388142 A/G cg20392616 chr7:135392013 SLC13A4 0.42 6.88 0.35 2.83e-11 Plantar warts; LIHC trans rs459571 0.635 rs379471 chr9:136890649 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.61 -9.49 -0.46 4.24e-19 Platelet distribution width; LIHC cis rs7572733 0.534 rs1589162 chr2:198782692 A/G cg00792783 chr2:198669748 PLCL1 0.45 6.68 0.34 9.45e-11 Dermatomyositis; LIHC cis rs2228479 0.850 rs1800331 chr16:89858417 C/A cg00800038 chr16:89945340 TCF25 -0.61 -8.73 -0.43 1.18e-16 Skin colour saturation; LIHC cis rs3749237 0.636 rs1568662 chr3:49521263 A/G cg03060546 chr3:49711283 APEH 0.63 10.23 0.48 1.35e-21 Resting heart rate; LIHC cis rs9443645 0.810 rs9361482 chr6:79750385 T/C cg05283184 chr6:79620031 NA -0.35 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC cis rs644799 0.542 rs10831417 chr11:95467262 A/G cg25622487 chr11:95524042 FAM76B;CEP57 -0.54 -7.02 -0.35 1.19e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs10213084 1.000 rs10010958 chr4:147511918 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.47 6.32 0.32 8.15e-10 Heart rate; LIHC cis rs1005277 0.505 rs1208689 chr10:38097775 C/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.56 -0.46 2.35e-19 Extrinsic epigenetic age acceleration; LIHC trans rs7246657 0.943 rs1373991 chr19:37838911 T/C cg24637308 chr11:6592297 DNHD1 0.43 6.09 0.31 2.99e-9 Coronary artery calcification; LIHC cis rs11673344 0.764 rs10403679 chr19:37471712 G/C cg27390819 chr19:37464633 NA -0.49 -5.91 -0.3 8.23e-9 Obesity-related traits; LIHC cis rs7116495 0.881 rs676721 chr11:71770638 G/A cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs1577917 0.771 rs12199873 chr6:86294947 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.99 -0.54 6.78e-28 Response to antipsychotic treatment; LIHC cis rs8062405 0.755 rs4788078 chr16:28559981 G/A cg16576597 chr16:28551801 NUPR1 0.49 7.76 0.39 9.79e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9814567 1.000 rs2370642 chr3:134222136 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.25 -0.55 7.24e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10540 1.000 rs61876336 chr11:489537 C/T cg03576123 chr11:487126 PTDSS2 -1.0 -7.62 -0.38 2.44e-13 Body mass index; LIHC cis rs12477438 0.520 rs1044575 chr2:99812070 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.9 13.32 0.58 6.85e-33 Chronic sinus infection; LIHC cis rs4930561 0.714 rs10896300 chr11:67953772 C/T cg04465784 chr11:67976953 SUV420H1 0.3 5.78 0.3 1.71e-8 Breast cancer in childhood cancer survivors;IgG glycosylation; LIHC trans rs890100 0.640 rs2193484 chr2:56687813 A/G cg27252696 chr6:100912940 SIM1 0.35 6.08 0.31 3.17e-9 Gut microbiome composition (summer); LIHC cis rs6733011 0.508 rs925887 chr2:99514671 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.4 6.48 0.33 3.17e-10 Bipolar disorder; LIHC cis rs1003719 0.788 rs7275582 chr21:38451130 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.79 12.61 0.56 3.36e-30 Eye color traits; LIHC trans rs2727020 0.729 rs10742932 chr11:49173234 T/C cg03929089 chr4:120376271 NA -0.78 -13.66 -0.59 3.21e-34 Coronary artery disease; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.67 9.44 0.45 5.93e-19 Lymphocyte counts; LIHC cis rs2153535 0.601 rs6906170 chr6:8543128 T/A cg07606381 chr6:8435919 SLC35B3 0.78 11.28 0.52 2.74e-25 Motion sickness; LIHC cis rs1577917 1.000 rs12205336 chr6:86722367 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.88 -0.35 2.82e-11 Response to antipsychotic treatment; LIHC cis rs1892700 0.840 rs74730233 chr21:34864391 G/T cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.97e-8 Educational attainment; LIHC cis rs765787 0.530 rs4775822 chr15:45527127 A/G cg25801113 chr15:45476975 SHF 0.37 6.36 0.33 6.62e-10 Uric acid levels; LIHC cis rs67311347 1.000 rs4973898 chr3:40459532 A/G cg13409248 chr3:40428643 ENTPD3 -0.44 -7.39 -0.37 1.11e-12 Renal cell carcinoma; LIHC cis rs3806843 1.000 rs3733708 chr5:140181734 A/G cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.65e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7568498 0.517 rs197261 chr2:161904823 A/G cg16506815 chr2:162101123 NA -0.42 -6.33 -0.32 7.64e-10 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC cis rs2723064 0.526 rs4671120 chr2:65371112 G/A cg05010058 chr2:65284262 CEP68 -0.36 -5.8 -0.3 1.51e-8 Atrial fibrillation; LIHC cis rs8084351 0.577 rs12965244 chr18:50663864 A/G cg24270629 chr18:50823537 DCC -0.44 -6.48 -0.33 3.12e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7786877 0.521 rs4729606 chr7:100321790 T/C cg16850897 chr7:100343110 ZAN -0.42 -6.09 -0.31 3.07e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2439831 1.000 rs2467743 chr15:43750346 T/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.57 0.59 7.69e-34 Lung cancer in ever smokers; LIHC cis rs875971 0.756 rs2901210 chr7:66017505 G/A cg11764359 chr7:65958608 NA -0.78 -13.63 -0.59 4.46e-34 Aortic root size; LIHC cis rs10857712 0.851 rs7913420 chr10:135213854 C/T cg01444801 chr10:135216882 MTG1 -0.66 -9.86 -0.47 2.39e-20 Systemic lupus erythematosus; LIHC cis rs992157 0.835 rs13005100 chr2:219151767 C/T cg00012203 chr2:219082015 ARPC2 -0.83 -13.21 -0.58 1.76e-32 Colorectal cancer; LIHC cis rs1005277 0.522 rs1208681 chr10:38092975 C/T cg25427524 chr10:38739819 LOC399744 -0.63 -12.01 -0.54 6.02e-28 Extrinsic epigenetic age acceleration; LIHC cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg06418219 chr1:154948305 SHC1;CKS1B -0.49 -6.95 -0.35 1.84e-11 Prostate cancer; LIHC trans rs9388451 0.839 rs10457469 chr6:126083658 G/A cg27561452 chr16:68573240 ZFP90 -0.41 -6.21 -0.32 1.58e-9 Brugada syndrome; LIHC cis rs7312933 0.558 rs61926593 chr12:42818912 C/T cg17420585 chr12:42539391 GXYLT1 -0.35 -5.72 -0.3 2.34e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs1459104 0.673 rs7118132 chr11:55126517 C/T cg15704280 chr7:45808275 SEPT13 0.58 8.03 0.4 1.57e-14 Body mass index; LIHC cis rs3020736 0.500 rs9620026 chr22:42498578 C/T cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs10065203 0.527 rs173948 chr5:14347771 A/G cg26595256 chr5:14380529 TRIO -0.4 -6.06 -0.31 3.57e-9 Paclitaxel-induced neuropathy; LIHC cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs7508679 1.000 rs10410204 chr19:7224350 C/T cg09779027 chr19:7224513 INSR 0.3 6.76 0.34 6.07e-11 Hypothyroidism; LIHC cis rs17384381 1.000 rs35193119 chr1:85859265 T/C cg16011679 chr1:85725395 C1orf52 0.83 8.63 0.42 2.35e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.659 rs34426768 chr17:56683385 C/T cg25039879 chr17:56429692 SUPT4H1 0.86 9.69 0.46 9e-20 Cognitive test performance; LIHC cis rs6120849 0.663 rs6088662 chr20:33547633 A/C cg06115741 chr20:33292138 TP53INP2 0.48 5.72 0.3 2.32e-8 Protein C levels; LIHC cis rs7091068 0.802 rs10786121 chr10:95419796 G/A cg20715218 chr10:95462985 C10orf4 0.56 6.2 0.32 1.67e-9 Urinary tract infection frequency; LIHC cis rs10504229 0.817 rs55891651 chr8:58167600 C/T cg02290350 chr8:58132656 NA 0.39 8.4 0.41 1.23e-15 Developmental language disorder (linguistic errors); LIHC trans rs6461049 0.734 rs1558465 chr7:2151398 G/C cg04565464 chr8:145669602 NFKBIL2 0.37 6.1 0.31 2.85e-9 Schizophrenia; LIHC cis rs4819052 0.851 rs2255774 chr21:46683851 A/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.69 0.5 3.24e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs3942852 0.774 rs2270990 chr11:48184983 G/T cg15704280 chr7:45808275 SEPT13 -0.59 -8.0 -0.4 1.95e-14 Acute lymphoblastic leukemia (childhood); LIHC trans rs2243480 1.000 rs6970243 chr7:65388490 C/A cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs7208859 0.623 rs9914242 chr17:29216245 G/T cg13385521 chr17:29058706 SUZ12P 0.79 7.69 0.38 1.61e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1005277 0.579 rs2103938 chr10:38493998 T/G cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.28 -0.32 1.01e-9 Extrinsic epigenetic age acceleration; LIHC cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg13395646 chr4:1353034 KIAA1530 -0.66 -9.42 -0.45 6.98e-19 Obesity-related traits; LIHC cis rs7208859 0.573 rs73267865 chr17:29064204 C/G cg14067834 chr17:29058358 SUZ12P 0.7 6.98 0.35 1.53e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9733 0.596 rs7412396 chr1:150666797 C/T cg17724175 chr1:150552817 MCL1 0.41 8.0 0.4 1.98e-14 Tonsillectomy; LIHC cis rs6669384 0.774 rs61821318 chr1:208033706 C/T cg22525895 chr1:207977042 MIR29B2 -0.54 -5.96 -0.31 6.45e-9 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs1005277 0.563 rs2505215 chr10:38481273 A/G cg00409905 chr10:38381863 ZNF37A -0.57 -9.48 -0.46 4.29e-19 Extrinsic epigenetic age acceleration; LIHC cis rs13336428 0.730 rs28653458 chr16:1525850 T/C cg07835181 chr16:1525278 CLCN7 0.68 12.01 0.54 5.77e-28 Bone mineral density; LIHC cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs3749237 0.595 rs12489092 chr3:49550914 G/C cg07636037 chr3:49044803 WDR6 0.53 8.15 0.4 6.85e-15 Resting heart rate; LIHC cis rs2710642 0.927 rs1468748 chr2:63204611 C/T cg17519650 chr2:63277830 OTX1 0.48 7.38 0.37 1.22e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg05590025 chr7:65112418 INTS4L2 0.44 6.6 0.34 1.6e-10 Calcium levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11823463 chr1:156629982 NA -0.56 -6.76 -0.34 6.11e-11 Systolic blood pressure; LIHC trans rs561341 0.709 rs11542477 chr17:30185892 A/G cg20587970 chr11:113659929 NA 0.65 6.51 0.33 2.7e-10 Hip circumference adjusted for BMI; LIHC trans rs11098499 0.863 rs10030660 chr4:120436704 G/A cg25214090 chr10:38739885 LOC399744 0.63 10.15 0.48 2.56e-21 Corneal astigmatism; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg10137979 chr8:110346498 ENY2;NUDCD1 0.43 6.62 0.34 1.37e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11792861 0.851 rs4542004 chr9:111814478 A/G cg13535736 chr9:111863775 C9orf5 -0.38 -5.71 -0.3 2.41e-8 Menarche (age at onset); LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.82 15.01 0.63 1.72e-39 Prudent dietary pattern; LIHC trans rs877282 0.898 rs71489279 chr10:760510 T/C cg22713356 chr15:30763199 NA 1.38 12.24 0.55 7.87e-29 Uric acid levels; LIHC cis rs3091242 0.933 rs28530483 chr1:25740847 A/C cg27572855 chr1:25598939 RHD 0.39 8.51 0.42 5.67e-16 Erythrocyte sedimentation rate; LIHC cis rs3096299 0.503 rs9925045 chr16:89556476 T/C cg08392591 chr16:89556376 ANKRD11 0.56 9.1 0.44 7.5e-18 Multiple myeloma (IgH translocation); LIHC cis rs10927875 0.864 rs12744578 chr1:16173110 A/T cg21385522 chr1:16154831 NA -1.07 -13.64 -0.59 4.14e-34 Dilated cardiomyopathy; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg04013166 chr16:89971882 TCF25 0.58 7.84 0.39 5.71e-14 Skin colour saturation; LIHC cis rs2370759 1.000 rs79806114 chr10:32618022 T/C cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg04025307 chr7:1156635 C7orf50 0.67 11.89 0.54 1.54e-27 Longevity;Endometriosis; LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg03721293 chr16:90014378 DEF8 0.41 6.95 0.35 1.83e-11 Skin colour saturation; LIHC cis rs9790314 1.000 rs336543 chr3:161061080 C/T cg03342759 chr3:160939853 NMD3 0.68 8.34 0.41 1.84e-15 Morning vs. evening chronotype; LIHC cis rs10847980 0.590 rs12299742 chr12:123323357 T/G cg22842854 chr12:123319900 HIP1R 0.83 9.26 0.45 2.24e-18 Adiponectin levels; LIHC cis rs4423214 0.879 rs1792277 chr11:71138918 C/T cg05163923 chr11:71159392 DHCR7 -0.64 -8.69 -0.43 1.56e-16 Vitamin D levels; LIHC cis rs2573652 1.000 rs2573651 chr15:100514109 T/G cg09918751 chr15:100517450 ADAMTS17 -0.82 -14.77 -0.62 1.55e-38 Height; LIHC cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.58 0.56 4.39e-30 Colorectal cancer; LIHC cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg03806693 chr22:41940476 POLR3H -1.08 -11.42 -0.53 8.04e-26 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9309473 0.950 rs10178678 chr2:73762236 A/G cg20560298 chr2:73613845 ALMS1 -0.57 -6.65 -0.34 1.14e-10 Metabolite levels; LIHC cis rs2836950 0.585 rs1029004 chr21:40615343 A/G cg06238570 chr21:40685208 BRWD1 -0.44 -7.18 -0.36 4.38e-12 Menarche (age at onset); LIHC cis rs7131987 0.834 rs7139273 chr12:29434650 T/C cg00204748 chr12:29376779 FAR2 0.35 6.61 0.34 1.47e-10 QT interval; LIHC cis rs2153535 0.580 rs9405390 chr6:8466209 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs743757 1.000 rs2236965 chr3:50453456 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.51 8.06 0.4 1.27e-14 Diastolic blood pressure; LIHC cis rs12549902 0.897 rs12549294 chr8:41506380 A/G cg21772509 chr8:41503840 NKX6-3 0.41 6.66 0.34 1.08e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs3736485 0.934 rs1902592 chr15:51881980 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs754466 0.580 rs10824575 chr10:79549047 A/G cg17075019 chr10:79541650 NA -0.79 -12.45 -0.56 1.38e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2845885 0.793 rs3751120 chr11:63884453 C/T cg18375707 chr11:64034959 PLCB3 -0.51 -7.83 -0.39 6.39e-14 Body mass index; LIHC trans rs17685 0.816 rs11763076 chr7:75765963 C/T cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3815700 1.000 rs8104729 chr19:33093979 C/T cg02997394 chr19:33096574 ANKRD27 0.72 9.25 0.45 2.55e-18 Eosinophilic esophagitis; LIHC cis rs4684776 0.676 rs11714563 chr3:11313214 A/G cg00170343 chr3:11313890 ATG7 -0.51 -6.95 -0.35 1.85e-11 Small vessel stroke; LIHC cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg25894440 chr7:65020034 NA -0.54 -6.1 -0.31 2.79e-9 Diabetic kidney disease; LIHC cis rs12586317 0.547 rs77780729 chr14:35496176 C/A cg16230307 chr14:35515116 FAM177A1 0.8 13.34 0.59 5.55e-33 Psoriasis; LIHC cis rs992157 0.697 rs13384682 chr2:219069137 G/A cg00012203 chr2:219082015 ARPC2 0.92 16.59 0.67 9.39e-46 Colorectal cancer; LIHC cis rs3790844 0.678 rs3790854 chr1:200000125 C/T cg13229857 chr1:200006247 NR5A2 -0.36 -5.98 -0.31 5.53e-9 Pancreatic cancer; LIHC cis rs3960554 1.000 rs2079477 chr7:75836549 C/G cg16684958 chr7:75615977 POR 0.4 5.96 0.31 6.36e-9 Eotaxin levels; LIHC cis rs2562152 0.706 rs216598 chr16:108585 T/C cg02949481 chr16:131562 MPG 0.44 6.81 0.35 4.52e-11 Glioblastoma; LIHC trans rs1814175 0.616 rs1794139 chr11:49910855 C/T cg15704280 chr7:45808275 SEPT13 -0.99 -20.32 -0.74 9.46e-61 Height; LIHC cis rs9513627 1.000 rs9517758 chr13:100179397 T/A cg25919922 chr13:100150906 NA 0.77 7.04 0.36 1.08e-11 Obesity-related traits; LIHC cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg13607699 chr17:42295918 UBTF 0.44 7.06 0.36 9.58e-12 Total body bone mineral density; LIHC cis rs6570726 0.791 rs6570695 chr6:145911286 C/A cg13319975 chr6:146136371 FBXO30 -0.4 -6.31 -0.32 8.87e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs78049276 0.736 rs6841581 chr4:148401190 C/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.57 -7.37 -0.37 1.27e-12 Pulse pressure; LIHC cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg09455208 chr3:40491958 NA -0.31 -6.37 -0.33 6.07e-10 Renal cell carcinoma; LIHC cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg09222892 chr1:25734099 RHCE -0.48 -8.65 -0.42 2.03e-16 Erythrocyte sedimentation rate; LIHC cis rs1005277 0.502 rs2800484 chr10:38542415 C/T cg17219203 chr10:38645113 HSD17B7P2 -0.39 -5.72 -0.3 2.34e-8 Extrinsic epigenetic age acceleration; LIHC cis rs35146811 0.844 rs13232115 chr7:99670932 T/C cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.41 5.93 0.31 7.43e-9 Coronary artery disease; LIHC cis rs1707322 1.000 rs10789479 chr1:46352500 T/C cg06784218 chr1:46089804 CCDC17 0.37 6.5 0.33 2.92e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8081395 0.866 rs2777899 chr17:57832391 T/G cg02344993 chr17:57696989 CLTC -0.45 -7.29 -0.37 2.22e-12 White blood cell count; LIHC cis rs8062405 0.755 rs12445823 chr16:28588049 A/C cg16576597 chr16:28551801 NUPR1 0.49 7.59 0.38 3.13e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2242116 0.796 rs4683296 chr3:46973820 G/C cg27129171 chr3:47204927 SETD2 -0.56 -9.05 -0.44 1.09e-17 Birth weight; LIHC cis rs6815814 0.808 rs4833093 chr4:38789740 G/T cg06935464 chr4:38784597 TLR10 0.52 8.89 0.43 3.48e-17 Breast cancer; LIHC cis rs4900538 0.963 rs1190554 chr14:102918686 T/C cg18135206 chr14:102964638 TECPR2 0.93 16.47 0.66 2.86e-45 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs8064024 0.680 rs3747613 chr16:4908504 C/G cg08329684 chr16:4932620 PPL -0.34 -5.93 -0.31 7.35e-9 Cancer; LIHC cis rs11212260 0.655 rs76734158 chr11:107204517 A/G cg25435332 chr11:107328525 CWF19L2 0.75 6.93 0.35 2.12e-11 IgG glycosylation; LIHC cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg14004847 chr7:1930337 MAD1L1 -0.48 -6.62 -0.34 1.43e-10 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs4803468 1.000 rs2241709 chr19:41912250 C/T cg14132834 chr19:41945861 ATP5SL -0.43 -6.29 -0.32 9.77e-10 Height; LIHC cis rs748404 0.723 rs512431 chr15:43541939 C/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.4 -6.19 -0.32 1.74e-9 Lung cancer; LIHC cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg03517284 chr6:25882590 NA -0.43 -6.58 -0.34 1.78e-10 Height; LIHC cis rs9309711 0.643 rs4264589 chr2:3481098 G/T cg15541040 chr2:3486749 NA -0.38 -6.0 -0.31 4.97e-9 Neurofibrillary tangles; LIHC cis rs7131987 0.903 rs11050153 chr12:29405148 T/C cg21486233 chr12:29375141 FAR2 0.32 6.51 0.33 2.72e-10 QT interval; LIHC cis rs243505 0.559 rs7802887 chr7:148494758 C/T cg09806900 chr7:148480153 CUL1 0.42 6.22 0.32 1.49e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg05535760 chr7:792225 HEATR2 0.49 6.77 0.34 5.77e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs12699477 0.545 rs117125814 chr7:1910681 T/G cg21782813 chr7:2030301 MAD1L1 0.41 6.9 0.35 2.58e-11 Testicular germ cell tumor; LIHC cis rs763121 0.853 rs5750662 chr22:39072472 G/A cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg10802521 chr3:52805072 NEK4 -0.45 -7.68 -0.38 1.67e-13 Electroencephalogram traits; LIHC cis rs4665809 1.000 rs7573118 chr2:26308086 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.99 -0.44 1.69e-17 Gut microbiome composition (summer); LIHC cis rs7587476 0.784 rs13008641 chr2:215698033 T/C cg04004882 chr2:215674386 BARD1 0.57 7.81 0.39 6.92e-14 Neuroblastoma; LIHC cis rs7589728 0.563 rs12479338 chr2:88444513 C/T cg07952391 chr2:88470173 THNSL2 0.8 7.56 0.38 3.78e-13 Plasma clusterin levels; LIHC cis rs3820068 0.655 rs59605679 chr1:15863796 T/G cg17385448 chr1:15911702 AGMAT 0.4 6.81 0.35 4.41e-11 Systolic blood pressure; LIHC cis rs1005277 0.579 rs2505241 chr10:38442421 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.95 -0.31 6.69e-9 Extrinsic epigenetic age acceleration; LIHC cis rs10197940 0.578 rs2045025 chr2:152317531 T/C cg06191203 chr2:152266755 RIF1 -0.41 -6.94 -0.35 1.99e-11 Lung cancer; LIHC cis rs912057 0.632 rs1294429 chr6:6744652 G/A cg06612196 chr6:6737390 NA 0.51 9.77 0.47 4.85e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs7523273 0.606 rs7144 chr1:207967719 A/G cg22525895 chr1:207977042 MIR29B2 -0.6 -9.9 -0.47 1.77e-20 Schizophrenia; LIHC cis rs6598955 0.670 rs7531518 chr1:26539749 T/C cg00852783 chr1:26633632 UBXN11 0.47 7.97 0.4 2.37e-14 Obesity-related traits; LIHC cis rs12220238 1.000 rs11000900 chr10:75918440 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.83 0.35 3.82e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2576037 0.583 rs2571028 chr18:44561100 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.74 -11.69 -0.53 8.9e-27 Personality dimensions; LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg18538332 chr22:24372958 LOC391322 0.48 6.52 0.33 2.55e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 6.22 0.32 1.45e-9 Electroencephalogram traits; LIHC cis rs208520 0.874 rs208517 chr6:66947040 G/T cg07460842 chr6:66804631 NA -0.69 -7.63 -0.38 2.29e-13 Exhaled nitric oxide output; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09034795 chr11:63676760 MARK2 0.41 6.36 0.33 6.66e-10 Longevity; LIHC cis rs651907 0.557 rs3864012 chr3:101397623 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.85 0.57 4.05e-31 Colorectal cancer; LIHC cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg14004847 chr7:1930337 MAD1L1 -0.49 -6.93 -0.35 2.13e-11 Bipolar disorder and schizophrenia; LIHC cis rs35110281 0.591 rs189094 chr21:44932017 A/G cg04455712 chr21:45112962 RRP1B 0.43 6.96 0.35 1.8e-11 Mean corpuscular volume; LIHC cis rs7712401 0.686 rs185007 chr5:122199318 C/T cg18764291 chr5:122110994 SNX2 0.33 5.82 0.3 1.37e-8 Mean platelet volume; LIHC cis rs34172651 0.517 rs200528 chr16:24759131 A/G cg00152838 chr16:24741724 TNRC6A 0.5 6.23 0.32 1.37e-9 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.740 rs2842614 chr6:86306069 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.47 -9.17 -0.44 4.37e-18 Response to antipsychotic treatment; LIHC cis rs7208859 0.524 rs11653098 chr17:29122501 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7666738 0.830 rs7669407 chr4:98750251 G/A cg05340658 chr4:99064831 C4orf37 0.64 11.59 0.53 2.03e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2404602 0.583 rs12592501 chr15:76554790 C/A cg03037974 chr15:76606532 NA 0.88 22.77 0.78 1.74e-70 Blood metabolite levels; LIHC cis rs28830936 0.528 rs11630242 chr15:42124643 T/C cg17847044 chr15:42102381 MAPKBP1 -0.46 -10.6 -0.5 6.67e-23 Diastolic blood pressure; LIHC cis rs2559856 1.000 rs2251187 chr12:102081889 G/A cg12924262 chr12:102091054 CHPT1 0.49 7.79 0.39 7.92e-14 Blood protein levels; LIHC cis rs6424115 0.867 rs34902309 chr1:24192200 A/G cg15997130 chr1:24165203 NA -0.41 -8.36 -0.41 1.55e-15 Immature fraction of reticulocytes; LIHC cis rs311392 0.554 rs395449 chr8:55100391 A/G cg11783602 chr8:55087084 NA -0.31 -6.16 -0.32 2.02e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs6540556 0.723 rs6752 chr1:209908100 G/A cg05527609 chr1:210001259 C1orf107 -0.57 -7.65 -0.38 2.13e-13 Red blood cell count; LIHC cis rs6466055 0.748 rs9640686 chr7:104867330 T/G cg04380332 chr7:105027541 SRPK2 0.36 6.71 0.34 8.29e-11 Schizophrenia; LIHC cis rs17685 0.753 rs8200 chr7:75696606 C/G cg16684958 chr7:75615977 POR -0.51 -8.59 -0.42 3.22e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7927592 0.956 rs7116899 chr11:68385535 G/T cg20283391 chr11:68216788 NA -0.51 -7.61 -0.38 2.73e-13 Total body bone mineral density; LIHC cis rs5758659 0.657 rs5758587 chr22:42517636 C/G cg19513890 chr22:42538836 CYP2D7P1 0.42 8.46 0.42 8.17e-16 Cognitive function; LIHC cis rs9473924 1.000 rs6923215 chr6:50889848 G/A cg14470998 chr6:50812995 TFAP2B 0.49 7.35 0.37 1.52e-12 Body mass index; LIHC cis rs11112613 0.713 rs11112589 chr12:105951226 C/G cg03607813 chr12:105948248 NA -0.61 -12.02 -0.54 5.41e-28 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7129556 0.520 rs10793257 chr11:77309533 T/C cg03570279 chr11:77446074 RSF1 -0.35 -6.47 -0.33 3.43e-10 Weight loss (gastric bypass surgery); LIHC cis rs936229 0.813 rs3784790 chr15:75081745 G/C cg14664628 chr15:75095509 CSK -1.02 -20.83 -0.75 8.16e-63 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs713477 1.000 rs12893000 chr14:55912280 G/T cg13175173 chr14:55914753 NA -0.36 -8.26 -0.41 3.34e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs9399135 0.967 rs9389261 chr6:135371148 C/G cg24558204 chr6:135376177 HBS1L 0.42 6.81 0.35 4.49e-11 Red blood cell count; LIHC trans rs783540 0.934 rs7182403 chr15:83297613 C/T cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.24 -0.32 1.33e-9 Schizophrenia; LIHC cis rs9910055 0.530 rs8072954 chr17:42294722 G/A cg19774624 chr17:42201019 HDAC5 -0.56 -7.86 -0.39 5.16e-14 Total body bone mineral density; LIHC cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg23758822 chr17:41437982 NA 0.97 18.36 0.7 6.68e-53 Menopause (age at onset); LIHC cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 6.81e-47 Diabetic kidney disease; LIHC cis rs853679 0.517 rs9380049 chr6:28048535 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs7659604 0.676 rs6534323 chr4:122695888 G/A cg19748678 chr4:122722346 EXOSC9 0.65 10.68 0.5 3.65e-23 Type 2 diabetes; LIHC cis rs6952808 0.600 rs2895202 chr7:2131829 T/C cg04267008 chr7:1944627 MAD1L1 -0.52 -8.03 -0.4 1.57e-14 Bipolar disorder and schizophrenia; LIHC cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg19539972 chr4:7069911 GRPEL1 0.66 9.53 0.46 2.96e-19 Monocyte percentage of white cells; LIHC cis rs17685 0.743 rs10277259 chr7:75802674 A/C cg04610667 chr7:75704037 NA -0.35 -6.18 -0.32 1.86e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7592578 0.771 rs10432434 chr2:191387079 T/G cg27211696 chr2:191398769 TMEM194B -0.6 -8.03 -0.4 1.55e-14 Diastolic blood pressure; LIHC cis rs3762637 0.941 rs9810999 chr3:122074391 G/A cg24169773 chr3:122142474 KPNA1 -0.49 -9.52 -0.46 3.18e-19 LDL cholesterol levels; LIHC cis rs36051895 0.664 rs12344629 chr9:5109208 C/T cg02405213 chr9:5042618 JAK2 -0.64 -10.8 -0.5 1.35e-23 Pediatric autoimmune diseases; LIHC cis rs7208859 0.725 rs7210904 chr17:29170205 G/A cg13385521 chr17:29058706 SUZ12P 0.75 7.63 0.38 2.35e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg16405210 chr4:1374714 KIAA1530 -0.47 -5.73 -0.3 2.23e-8 Obesity-related traits; LIHC cis rs4253772 0.591 rs8143066 chr22:46656607 C/T cg09491104 chr22:46646882 C22orf40 -0.65 -7.57 -0.38 3.45e-13 LDL cholesterol;Cholesterol, total; LIHC cis rs6121246 0.909 rs6060870 chr20:30303299 C/T cg13852791 chr20:30311386 BCL2L1 0.97 9.8 0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs4665809 0.878 rs35709953 chr2:26334997 G/A cg27170947 chr2:26402098 FAM59B 0.58 6.29 0.32 9.7e-10 Gut microbiome composition (summer); LIHC cis rs10751667 1.000 rs7394449 chr11:962190 T/C cg10932868 chr11:921992 NA 0.35 6.4 0.33 5.15e-10 Alzheimer's disease (late onset); LIHC cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1865760 1.000 rs3752421 chr6:25918688 G/A cg03517284 chr6:25882590 NA -0.38 -5.76 -0.3 1.83e-8 Height; LIHC cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.46 -8.52 -0.42 5.35e-16 Total body bone mineral density; LIHC cis rs780096 0.587 rs4665969 chr2:27574953 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 0.37 5.75 0.3 1.94e-8 Total body bone mineral density; LIHC cis rs9467773 1.000 rs6924838 chr6:26571756 C/T cg11502198 chr6:26597334 ABT1 0.47 6.84 0.35 3.7e-11 Intelligence (multi-trait analysis); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg05930370 chr1:224545104 CNIH4 -0.44 -6.09 -0.31 3.07e-9 Alopecia areata; LIHC cis rs7959452 0.558 rs1478464 chr12:69779789 G/C cg14784868 chr12:69753453 YEATS4 0.94 20.21 0.74 2.5e-60 Blood protein levels; LIHC cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg12373951 chr3:133503437 NA 0.46 7.65 0.38 2.03e-13 Iron status biomarkers; LIHC cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg13397359 chr6:42928475 GNMT 0.83 12.2 0.55 1.1e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs12586317 0.547 rs77262907 chr14:35495734 C/G cg16230307 chr14:35515116 FAM177A1 0.78 13.24 0.58 1.39e-32 Psoriasis; LIHC cis rs61677309 1.000 rs56140791 chr11:118167190 T/C cg06090739 chr11:118230722 UBE4A 0.35 6.41 0.33 4.8e-10 Lung cancer in ever smokers; LIHC cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg09417038 chr21:47716443 C21orf57 -0.54 -8.07 -0.4 1.19e-14 Testicular germ cell tumor; LIHC cis rs12549902 0.800 rs7825337 chr8:41507237 C/T cg21772509 chr8:41503840 NKX6-3 0.38 6.44 0.33 4.04e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs1865760 0.566 rs9348706 chr6:26065481 G/C cg17691542 chr6:26056736 HIST1H1C 0.42 6.06 0.31 3.63e-9 Height; LIHC cis rs3749237 0.576 rs3877784 chr3:49539417 C/T cg07636037 chr3:49044803 WDR6 0.56 8.42 0.41 1.03e-15 Resting heart rate; LIHC cis rs9916302 0.904 rs57399933 chr17:37551189 A/G cg03013999 chr17:37608204 MED1 -0.35 -5.8 -0.3 1.49e-8 Glomerular filtration rate (creatinine); LIHC cis rs9473924 0.542 rs2245173 chr6:50810540 T/C cg14470998 chr6:50812995 TFAP2B 0.98 11.36 0.52 1.42e-25 Body mass index; LIHC cis rs9399135 0.967 rs1041481 chr6:135335063 G/A cg24558204 chr6:135376177 HBS1L 0.42 6.95 0.35 1.91e-11 Red blood cell count; LIHC cis rs34172651 0.617 rs9922436 chr16:24704490 C/G cg00339695 chr16:24857497 SLC5A11 0.48 7.94 0.39 2.86e-14 Intelligence (multi-trait analysis); LIHC cis rs763121 0.962 rs6001193 chr22:39074737 A/G cg06022373 chr22:39101656 GTPBP1 0.67 12.77 0.57 8.25e-31 Menopause (age at onset); LIHC cis rs17253792 0.915 rs77252471 chr14:56178075 C/T cg01858014 chr14:56050164 KTN1 -0.76 -8.08 -0.4 1.1e-14 Putamen volume; LIHC cis rs2404602 0.684 rs965818 chr15:76866785 T/C cg23625390 chr15:77176239 SCAPER -0.55 -9.15 -0.44 5.23e-18 Blood metabolite levels; LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg20607798 chr8:58055168 NA 0.63 7.96 0.4 2.64e-14 Developmental language disorder (linguistic errors); LIHC cis rs9392556 0.510 rs613028 chr6:4102139 C/T cg08342332 chr6:4079704 C6orf201;C6orf146 -0.31 -5.86 -0.3 1.08e-8 Blood metabolite levels; LIHC cis rs6867032 1.000 rs16902318 chr5:2013568 A/G cg26168224 chr5:2018326 NA 0.32 8.18 0.4 5.75e-15 Gut microbiome composition (winter); LIHC cis rs72772090 0.634 rs10515246 chr5:96099265 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.63 -7.08 -0.36 8.02e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs3784262 0.967 rs35511675 chr15:58266978 T/A cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.31 -0.32 8.7e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs623264 0.920 rs415427 chr19:5470637 T/G cg03088458 chr19:5478473 NA -0.35 -6.04 -0.31 4.05e-9 Interleukin-2 receptor antagonist levels; LIHC cis rs7267979 0.966 rs2145126 chr20:25263648 G/A cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs5758659 0.714 rs5758574 chr22:42481400 G/C cg19513890 chr22:42538836 CYP2D7P1 0.42 8.25 0.41 3.58e-15 Cognitive function; LIHC cis rs2549003 1.000 rs9282763 chr5:131822133 T/C cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg12310025 chr6:25882481 NA -0.64 -9.01 -0.44 1.54e-17 Blood metabolite levels; LIHC cis rs2834188 1.000 rs2834188 chr21:34689253 A/G cg04842828 chr21:34696676 IFNAR1 0.45 6.14 0.32 2.31e-9 Narcolepsy; LIHC cis rs11676348 0.873 rs10210012 chr2:219013334 G/A cg00012203 chr2:219082015 ARPC2 -0.46 -5.83 -0.3 1.31e-8 Ulcerative colitis; LIHC cis rs9929218 0.861 rs4783667 chr16:68752878 C/A cg01231543 chr16:68741748 NA 0.36 5.72 0.3 2.32e-8 Colorectal cancer; LIHC cis rs910316 0.737 rs175080 chr14:75513828 G/A cg11812906 chr14:75593930 NEK9 -0.76 -14.3 -0.61 1.07e-36 Height; LIHC cis rs80282103 0.571 rs10047269 chr10:1103058 G/A cg20335179 chr10:1068567 C10orf110;IDI2 -0.54 -5.72 -0.3 2.35e-8 Glomerular filtration rate (creatinine); LIHC cis rs7223966 1.000 rs7220821 chr17:61704147 G/A cg05941027 chr17:61774174 LIMD2 0.31 6.34 0.32 7.07e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9818758 0.607 rs13068038 chr3:49294250 C/A cg06212747 chr3:49208901 KLHDC8B -0.66 -5.87 -0.3 1.01e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs4409675 0.576 rs2749119 chr1:28236248 G/A cg23691781 chr1:28212827 C1orf38 0.32 7.58 0.38 3.28e-13 Corneal astigmatism; LIHC cis rs1982963 0.950 rs2645738 chr14:52513202 G/A cg10843707 chr14:52510701 NID2 -0.48 -8.55 -0.42 4.22e-16 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg18252515 chr7:66147081 NA 1.28 16.92 0.68 4.2e-47 Diabetic kidney disease; LIHC cis rs6952808 0.531 rs3779002 chr7:2183219 C/T cg02951883 chr7:2050386 MAD1L1 -0.62 -9.85 -0.47 2.6e-20 Bipolar disorder and schizophrenia; LIHC cis rs9534288 0.797 rs2404728 chr13:46581862 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs8078723 1.000 rs3213762 chr17:38178627 A/G cg17467752 chr17:38218738 THRA 0.75 13.33 0.58 6.41e-33 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg09367891 chr1:107599246 PRMT6 0.71 11.88 0.54 1.68e-27 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs1814175 0.791 rs1722023 chr11:49908136 G/C cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs9611519 0.780 rs9611546 chr22:41698542 C/G cg06481639 chr22:41940642 POLR3H -0.53 -5.75 -0.3 2.01e-8 Neuroticism; LIHC cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg25894440 chr7:65020034 NA 0.53 6.04 0.31 4.03e-9 Diabetic kidney disease; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01719141 chr9:140513215 C9orf37;EHMT1 -0.41 -6.5 -0.33 2.87e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1801251 0.896 rs4973561 chr2:233687337 C/G cg25237894 chr2:233734115 C2orf82 -0.55 -10.43 -0.49 2.66e-22 Coronary artery disease; LIHC cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg25894440 chr7:65020034 NA -0.55 -6.21 -0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs2292096 0.850 rs12760892 chr1:200802901 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -6.07 -0.31 3.33e-9 Epilepsy; LIHC cis rs8017423 0.935 rs11628952 chr14:90734953 T/C cg14092571 chr14:90743983 NA 0.46 7.32 0.37 1.8e-12 Mortality in heart failure; LIHC cis rs9322817 0.691 rs2499660 chr6:105285750 T/C cg02098413 chr6:105308735 HACE1 0.44 8.27 0.41 3.04e-15 Thyroid stimulating hormone; LIHC cis rs903552 0.932 rs9806551 chr15:102008206 C/T cg25677261 chr15:102009856 PCSK6 -0.5 -6.83 -0.35 3.88e-11 Diabetic kidney disease; LIHC cis rs2576037 0.526 rs564113 chr18:44364389 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.63 9.83 0.47 3.02e-20 Personality dimensions; LIHC cis rs2359239 0.519 rs8007145 chr14:75185748 T/A cg11812906 chr14:75593930 NEK9 0.42 6.36 0.33 6.53e-10 Neuroticism (multi-trait analysis); LIHC cis rs600231 0.706 rs10896016 chr11:65335705 C/T cg10628098 chr11:65292300 SCYL1 -0.37 -5.88 -0.3 9.7e-9 Bone mineral density; LIHC trans rs3812049 0.826 rs17764730 chr5:127357526 A/G cg16011800 chr17:1958478 HIC1 -0.5 -7.33 -0.37 1.67e-12 Lymphocyte counts;Red cell distribution width; LIHC cis rs7772486 0.558 rs62435775 chr6:146136415 G/C cg23711669 chr6:146136114 FBXO30 0.64 9.73 0.47 6.66e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6754311 0.550 rs1438307 chr2:136499166 A/C cg15123519 chr2:136567270 LCT -0.43 -8.67 -0.42 1.8e-16 Mosquito bite size; LIHC cis rs35306767 0.904 rs35667562 chr10:950630 G/A cg26597838 chr10:835615 NA 1.46 16.4 0.66 5.12e-45 Eosinophil percentage of granulocytes; LIHC cis rs1005277 0.579 rs2504143 chr10:38383706 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC trans rs2018683 0.870 rs13232487 chr7:28985119 C/A cg19402173 chr7:128379420 CALU -0.4 -6.41 -0.33 4.78e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs8081395 0.775 rs2526355 chr17:57953233 G/C cg13753209 chr17:57696993 CLTC 0.38 5.83 0.3 1.27e-8 White blood cell count; LIHC cis rs6665290 0.904 rs6426559 chr1:227195876 T/C cg10327440 chr1:227177885 CDC42BPA -1.18 -25.93 -0.81 1e-82 Myeloid white cell count; LIHC cis rs10504229 0.610 rs6987118 chr8:58147851 G/T cg21724239 chr8:58056113 NA 0.49 6.45 0.33 3.82e-10 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg20295408 chr7:1910781 MAD1L1 -0.48 -6.93 -0.35 2.08e-11 Bipolar disorder and schizophrenia; LIHC cis rs9291683 0.588 rs13113730 chr4:10017628 C/T cg11266682 chr4:10021025 SLC2A9 0.33 7.15 0.36 5.29e-12 Bone mineral density; LIHC cis rs12200782 0.505 rs7765920 chr6:26514771 C/T cg11502198 chr6:26597334 ABT1 0.78 9.16 0.44 4.82e-18 Small cell lung carcinoma; LIHC cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6582630 0.500 rs35251810 chr12:38577666 T/C cg26384229 chr12:38710491 ALG10B -0.49 -6.95 -0.35 1.88e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg03264133 chr6:25882463 NA -0.96 -12.59 -0.56 4.07e-30 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.963 rs11211202 chr1:46292382 C/T cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.77e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs748404 0.697 rs504417 chr15:43554226 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.71 0.34 8.14e-11 Lung cancer; LIHC cis rs644799 0.965 rs545342 chr11:95545369 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.76 0.47 5.11e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12594515 1.000 rs6493167 chr15:45986809 G/A cg01629716 chr15:45996671 NA 0.52 9.65 0.46 1.25e-19 Waist circumference;Weight; LIHC cis rs9902453 1.000 rs4795525 chr17:28388487 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs743757 0.878 rs12494849 chr3:50524558 C/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.41 6.29 0.32 9.87e-10 Diastolic blood pressure; LIHC cis rs35110281 0.714 rs7277539 chr21:45053011 A/G cg04455712 chr21:45112962 RRP1B 0.47 8.02 0.4 1.65e-14 Mean corpuscular volume; LIHC cis rs12893668 0.645 rs12889403 chr14:104034746 C/T cg24130564 chr14:104152367 KLC1 -0.55 -8.9 -0.43 3.42e-17 Reticulocyte count; LIHC cis rs709400 0.930 rs10134399 chr14:104083457 G/A cg26031613 chr14:104095156 KLC1 1.16 15.38 0.64 6.25e-41 Body mass index; LIHC cis rs7945705 0.902 rs11042152 chr11:9020987 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.4 6.51 0.33 2.7e-10 Hemoglobin concentration; LIHC cis rs2836974 0.565 rs34304022 chr21:40579619 G/A cg11890956 chr21:40555474 PSMG1 0.97 9.47 0.46 4.69e-19 Cognitive function; LIHC cis rs7552404 1.000 rs6593585 chr1:76140273 G/A cg03433033 chr1:76189801 ACADM 0.67 9.65 0.46 1.24e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg19536664 chr17:6899085 ALOX12 -0.32 -5.94 -0.31 6.87e-9 Tonsillectomy; LIHC cis rs1577917 0.958 rs10944136 chr6:86448499 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.08 -0.31 3.22e-9 Response to antipsychotic treatment; LIHC cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg11502198 chr6:26597334 ABT1 0.62 9.76 0.47 5.15e-20 Intelligence (multi-trait analysis); LIHC cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg14983838 chr19:29218262 NA 0.48 7.51 0.38 5.23e-13 Methadone dose in opioid dependence; LIHC cis rs17253792 0.545 rs34446601 chr14:56010586 A/G cg01858014 chr14:56050164 KTN1 -0.63 -5.89 -0.3 9.13e-9 Putamen volume; LIHC cis rs67478160 0.619 rs11160761 chr14:104254856 A/T cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.43 -0.37 8.66e-13 Schizophrenia; LIHC cis rs2455601 0.671 rs10840135 chr11:8879794 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -8.48 -0.42 6.86e-16 Schizophrenia; LIHC cis rs9399135 0.967 rs4451151 chr6:135310546 C/T cg22676075 chr6:135203613 NA 0.4 6.45 0.33 3.87e-10 Red blood cell count; LIHC cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.27 -0.45 2.12e-18 Bipolar disorder; LIHC cis rs4450131 0.522 rs11245328 chr10:126358413 G/A cg20435097 chr10:126320824 FAM53B 0.67 12.33 0.55 3.71e-29 White blood cell count (basophil); LIHC cis rs561341 0.882 rs2428337 chr17:30299467 C/T cg00745463 chr17:30367425 LRRC37B -0.77 -5.72 -0.3 2.34e-8 Hip circumference adjusted for BMI; LIHC cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.49e-29 Menopause (age at onset); LIHC cis rs7100689 0.646 rs10736348 chr10:82139244 C/A cg01528321 chr10:82214614 TSPAN14 0.85 12.35 0.56 3.15e-29 Post bronchodilator FEV1; LIHC cis rs1949733 0.656 rs2631762 chr4:8423122 A/T cg11789530 chr4:8429930 ACOX3 0.75 11.09 0.51 1.3e-24 Response to antineoplastic agents; LIHC cis rs7264396 0.623 rs6060507 chr20:34198334 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -8.73 -0.43 1.11e-16 Total cholesterol levels; LIHC cis rs10256972 0.684 rs2363279 chr7:1096143 A/G cg04025307 chr7:1156635 C7orf50 0.55 8.86 0.43 4.49e-17 Longevity;Endometriosis; LIHC cis rs1862618 0.671 rs72644088 chr5:56241019 G/A cg24531977 chr5:56204891 C5orf35 0.52 7.67 0.38 1.77e-13 Initial pursuit acceleration; LIHC cis rs138857 0.515 rs9616373 chr22:50308597 G/A cg02269571 chr22:50332266 NA -0.98 -10.11 -0.48 3.45e-21 Mean platelet volume; LIHC cis rs3768617 0.510 rs10911254 chr1:183088627 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs965469 1.000 rs6051807 chr20:3350485 A/G cg25506879 chr20:3388711 C20orf194 -0.55 -6.24 -0.32 1.32e-9 IFN-related cytopenia; LIHC cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg26818010 chr10:134567672 INPP5A -0.77 -9.41 -0.45 7.23e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17253792 0.822 rs10083303 chr14:56068521 T/C cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs1997103 0.954 rs940880 chr7:55392619 C/G cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.45e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs10463316 0.894 rs4099171 chr5:150766623 C/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.07e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7523273 0.606 rs2761430 chr1:207912408 G/A cg22525895 chr1:207977042 MIR29B2 0.61 10.03 0.48 6.27e-21 Schizophrenia; LIHC cis rs10771431 0.817 rs10843149 chr12:9362067 G/A cg08997352 chr12:9597637 DDX12 -0.54 -8.45 -0.42 8.72e-16 Breast size; LIHC cis rs6952808 0.500 rs3778996 chr7:2177190 G/A cg04267008 chr7:1944627 MAD1L1 -0.49 -7.57 -0.38 3.62e-13 Bipolar disorder and schizophrenia; LIHC cis rs8063761 0.640 rs4785760 chr16:90051438 G/A cg05185784 chr16:90016020 DEF8 0.38 6.24 0.32 1.28e-9 Squamous cell carcinoma; LIHC cis rs709400 1.000 rs861538 chr14:104166733 C/T cg26031613 chr14:104095156 KLC1 1.03 12.95 0.57 1.77e-31 Body mass index; LIHC cis rs2304069 0.545 rs6866616 chr5:149415401 A/G cg12661370 chr5:149340060 SLC26A2 0.56 8.4 0.41 1.21e-15 HIV-1 control; LIHC cis rs708547 0.647 rs1718831 chr4:57886946 T/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.45 6.59 0.34 1.63e-10 Response to bleomycin (chromatid breaks); LIHC cis rs875971 1.000 rs1544549 chr7:66090663 T/A cg12463550 chr7:65579703 CRCP -0.41 -5.75 -0.3 2e-8 Aortic root size; LIHC cis rs9611565 0.694 rs9611591 chr22:41830212 G/A cg03806693 chr22:41940476 POLR3H 0.55 7.32 0.37 1.84e-12 Vitiligo; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg09455208 chr3:40491958 NA 0.39 7.83 0.39 6.2e-14 Renal cell carcinoma; LIHC cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg27211696 chr2:191398769 TMEM194B -0.67 -11.22 -0.52 4.23e-25 Pulse pressure; LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.55 -7.76 -0.39 1e-13 Lymphocyte counts; LIHC trans rs11098499 0.863 rs1552095 chr4:120460306 A/G cg25214090 chr10:38739885 LOC399744 0.6 9.59 0.46 1.84e-19 Corneal astigmatism; LIHC cis rs6430585 0.941 rs6708957 chr2:136520043 C/T cg07169764 chr2:136633963 MCM6 1.04 14.23 0.61 1.99e-36 Corneal structure; LIHC cis rs10779751 0.922 rs2295080 chr1:11322628 G/T cg08854313 chr1:11322531 MTOR 0.9 17.17 0.68 4.23e-48 Body mass index; LIHC cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg04727924 chr7:799746 HEATR2 0.41 6.28 0.32 1.01e-9 Perceived unattractiveness to mosquitoes; LIHC cis rs2108622 0.727 rs62107764 chr19:15982658 A/G cg13772218 chr19:15982569 NA 0.37 7.75 0.39 1.06e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs7208859 0.673 rs73263785 chr17:29214808 C/T cg14067834 chr17:29058358 SUZ12P 0.67 6.48 0.33 3.26e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1914816 0.941 rs2469544 chr15:76484947 A/T cg03037974 chr15:76606532 NA -0.59 -6.11 -0.31 2.67e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg12311346 chr5:56204834 C5orf35 -0.67 -8.59 -0.42 3.04e-16 Initial pursuit acceleration; LIHC cis rs2180341 0.960 rs9375503 chr6:127677071 T/C cg27446573 chr6:127587934 RNF146 1.07 16.7 0.67 3.25e-46 Breast cancer; LIHC cis rs4665809 0.941 rs2289021 chr2:26362515 A/C cg26119090 chr2:26468346 HADHA;HADHB 0.77 9.89 0.47 1.92e-20 Gut microbiome composition (summer); LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg12419862 chr22:24373484 LOC391322 -0.72 -11.2 -0.52 5.23e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7904368 0.707 rs12253979 chr10:16853415 T/C cg14835575 chr10:16859367 RSU1 0.63 8.63 0.42 2.28e-16 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs7618501 0.933 rs3811695 chr3:49761613 C/T cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg06497051 chr1:156261200 TMEM79 0.38 6.19 0.32 1.77e-9 Tonsillectomy; LIHC trans rs11098499 0.865 rs2389809 chr4:120377399 T/C cg25214090 chr10:38739885 LOC399744 0.59 9.71 0.46 7.58e-20 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22807378 chr6:170151601 TCTE3;C6orf70 -0.48 -6.6 -0.34 1.57e-10 Pancreatic cancer; LIHC cis rs17401966 0.931 rs61778401 chr1:10426474 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.75 -0.34 6.16e-11 Hepatocellular carcinoma; LIHC cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg00684032 chr4:1343700 KIAA1530 0.4 6.85 0.35 3.34e-11 Obesity-related traits; LIHC cis rs7647973 0.925 rs11130183 chr3:49228946 A/G cg07636037 chr3:49044803 WDR6 0.51 6.49 0.33 2.98e-10 Menarche (age at onset); LIHC cis rs6138458 0.962 rs6036976 chr20:24901567 T/G cg26195577 chr20:24973756 C20orf3 -1.09 -13.71 -0.6 2.13e-34 Blood protein levels; LIHC cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg20607798 chr8:58055168 NA 0.6 7.26 0.37 2.58e-12 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg06481639 chr22:41940642 POLR3H -0.72 -6.98 -0.35 1.55e-11 Vitiligo; LIHC cis rs6565180 1.000 rs11646130 chr16:30376959 T/C cg17640201 chr16:30407289 ZNF48 -0.78 -12.42 -0.56 1.75e-29 Tonsillectomy; LIHC cis rs11122272 0.766 rs2024879 chr1:231528638 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg09455208 chr3:40491958 NA 0.42 8.48 0.42 6.71e-16 Renal cell carcinoma; LIHC cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg20607798 chr8:58055168 NA 0.49 6.21 0.32 1.51e-9 Developmental language disorder (linguistic errors); LIHC cis rs9549367 0.789 rs2302757 chr13:113909339 A/G cg00898013 chr13:113819073 PROZ -0.42 -7.16 -0.36 5.08e-12 Platelet distribution width; LIHC cis rs12291225 0.679 rs11238 chr11:14288128 A/C cg05501817 chr11:14380813 RRAS2 0.43 5.87 0.3 1.03e-8 Sense of smell; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg18110333 chr6:292329 DUSP22 -0.53 -6.9 -0.35 2.49e-11 Menopause (age at onset); LIHC cis rs9399137 0.507 rs7748708 chr6:135275142 G/A cg24558204 chr6:135376177 HBS1L 0.6 10.26 0.49 1.05e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs2404602 0.632 rs34338978 chr15:77226805 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.83 0.3 1.25e-8 Blood metabolite levels; LIHC cis rs1008375 0.966 rs6833808 chr4:17652526 T/A cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg21724239 chr8:58056113 NA 0.58 7.48 0.38 6.22e-13 Developmental language disorder (linguistic errors); LIHC cis rs7568458 0.660 rs6547623 chr2:85801964 T/A cg02493740 chr2:85810744 VAMP5 -0.45 -7.49 -0.38 5.97e-13 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1559088 0.948 rs10406916 chr19:33590093 G/A cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7178375 1.000 rs11070678 chr15:31219764 A/G cg19680485 chr15:31195859 MTMR15 -0.54 -5.97 -0.31 5.95e-9 Hypertriglyceridemia; LIHC cis rs7927592 0.956 rs10896341 chr11:68313180 G/A cg16797656 chr11:68205561 LRP5 0.51 8.04 0.4 1.47e-14 Total body bone mineral density; LIHC cis rs1564271 0.553 rs2489583 chr10:26987698 A/G cg13837822 chr10:26931731 LOC731789 0.36 6.66 0.34 1.1e-10 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg27432699 chr2:27873401 GPN1 -0.52 -7.38 -0.37 1.22e-12 Total body bone mineral density; LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg22963979 chr7:1858916 MAD1L1 -0.45 -7.27 -0.37 2.51e-12 Bipolar disorder and schizophrenia; LIHC cis rs12477438 0.798 rs6542848 chr2:99573732 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.07 -14.9 -0.63 4.91e-39 Chronic sinus infection; LIHC cis rs7937682 0.921 rs4534611 chr11:111440425 C/G cg09085632 chr11:111637200 PPP2R1B -0.85 -9.91 -0.47 1.66e-20 Primary sclerosing cholangitis; LIHC cis rs7246657 0.941 rs67293224 chr19:37803248 C/T cg23950597 chr19:37808831 NA -0.52 -6.56 -0.33 2.03e-10 Coronary artery calcification; LIHC cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.52 -0.56 7.42e-30 Alzheimer's disease; LIHC cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg03188948 chr7:1209495 NA 0.87 6.33 0.32 7.7e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4820294 0.669 rs7287340 chr22:38054325 C/T cg26138144 chr22:38071188 LGALS1 0.42 7.83 0.39 6.21e-14 Fat distribution (HIV); LIHC cis rs3845702 0.800 rs6744281 chr2:180844382 G/A cg01881094 chr2:180872142 CWC22 -1.14 -10.21 -0.48 1.54e-21 Schizophrenia; LIHC cis rs6860806 0.507 rs270608 chr5:131648406 C/T cg24060327 chr5:131705240 SLC22A5 -0.81 -12.39 -0.56 2.19e-29 Breast cancer; LIHC cis rs11098499 0.863 rs10018280 chr4:120478139 T/G cg09307838 chr4:120376055 NA 0.74 11.27 0.52 3e-25 Corneal astigmatism; LIHC cis rs7927592 0.871 rs55953412 chr11:68328283 C/T cg20283391 chr11:68216788 NA -0.51 -7.65 -0.38 2.04e-13 Total body bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06009330 chr2:70485380 PCYOX1 -0.43 -6.3 -0.32 8.99e-10 Cognitive function; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg06795559 chr20:5931181 MCM8;TRMT6 0.41 6.12 0.31 2.52e-9 Calcium levels; LIHC cis rs67311347 1.000 rs12638199 chr3:40475285 A/G cg00656387 chr3:40428638 ENTPD3 0.41 6.91 0.35 2.32e-11 Renal cell carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04873026 chr21:30365177 RNF160 0.44 6.05 0.31 3.84e-9 Lung function (FEV1/FVC); LIHC cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg08645402 chr16:4508243 NA 0.39 7.16 0.36 4.85e-12 Schizophrenia; LIHC cis rs757081 0.634 rs17472942 chr11:17094702 A/G cg15432903 chr11:17409602 KCNJ11 -0.42 -5.85 -0.3 1.17e-8 Systolic blood pressure; LIHC cis rs4407350 0.837 rs5765707 chr22:44909507 A/T cg26276947 chr22:44892394 LDOC1L 0.35 6.55 0.33 2.13e-10 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs7116495 0.609 rs2511120 chr11:71786211 C/T cg26138937 chr11:71823887 C11orf51 -1.32 -10.43 -0.49 2.71e-22 Severe influenza A (H1N1) infection; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18525740 chr5:176449647 ZNF346 0.4 6.06 0.31 3.63e-9 Cognitive function; LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs1538970 0.962 rs7532762 chr1:45864695 C/A cg05343316 chr1:45956843 TESK2 0.51 7.64 0.38 2.2e-13 Platelet count; LIHC cis rs3806843 0.735 rs2530241 chr5:140054485 C/T cg16179182 chr5:140090404 VTRNA1-1 0.36 5.94 0.31 6.89e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs3204270 0.639 rs62080213 chr17:79642531 C/T cg18367735 chr17:79674897 NA 0.71 7.87 0.39 4.71e-14 Dental caries; LIHC cis rs6088580 0.524 rs6088569 chr20:33268199 G/A cg07148914 chr20:33460835 GGT7 -0.52 -7.28 -0.37 2.37e-12 Glomerular filtration rate (creatinine); LIHC trans rs668210 0.793 rs502363 chr11:65775592 C/T cg17712092 chr4:129076599 LARP1B 0.59 6.56 0.33 1.95e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs17102884 0.587 rs10162454 chr14:75144618 T/C cg08847533 chr14:75593920 NEK9 0.42 6.29 0.32 9.82e-10 Neuroticism; LIHC cis rs2115630 0.967 rs11073702 chr15:85310071 G/A cg12501888 chr15:85177176 SCAND2 -0.51 -8.02 -0.4 1.71e-14 P wave terminal force; LIHC cis rs2204008 0.548 rs8189475 chr12:38037115 C/T cg26384229 chr12:38710491 ALG10B 0.51 7.02 0.36 1.18e-11 Bladder cancer; LIHC cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC cis rs7635838 0.684 rs384989 chr3:11320120 C/T cg00170343 chr3:11313890 ATG7 0.56 9.48 0.46 4.51e-19 HDL cholesterol; LIHC cis rs4819052 1.000 rs9984901 chr21:46663952 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.69 9.41 0.45 7.28e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs911119 0.657 rs6114214 chr20:23627924 A/T cg23114964 chr1:42217077 HIVEP3 0.43 6.5 0.33 2.89e-10 Chronic kidney disease; LIHC cis rs9303401 0.632 rs7222087 chr17:57221619 A/T cg12560992 chr17:57184187 TRIM37 0.54 7.34 0.37 1.56e-12 Cognitive test performance; LIHC cis rs898097 0.625 rs2125479 chr17:80890262 A/G cg15664640 chr17:80829946 TBCD -0.42 -7.0 -0.35 1.32e-11 Breast cancer; LIHC cis rs4975709 0.610 rs1531994 chr5:1859297 T/C cg15595755 chr5:1867978 NA 0.41 8.09 0.4 1.07e-14 Cardiovascular disease risk factors; LIHC cis rs2075371 0.871 rs418135 chr7:133949898 A/G cg11752832 chr7:134001865 SLC35B4 0.53 8.04 0.4 1.48e-14 Mean platelet volume; LIHC cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.89 0.57 2.95e-31 Alzheimer's disease; LIHC cis rs8084351 0.599 rs12454142 chr18:50676918 G/A cg24270629 chr18:50823537 DCC -0.45 -6.67 -0.34 1.01e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs6545883 0.859 rs35760550 chr2:61603865 T/A cg14146966 chr2:61757674 XPO1 -0.44 -7.3 -0.37 2.09e-12 Tuberculosis; LIHC cis rs2576037 0.583 rs9954336 chr18:44465945 A/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.21 -0.36 3.7e-12 Personality dimensions; LIHC cis rs427394 0.796 rs274683 chr5:6747950 T/A cg10857441 chr5:6722123 POLS -0.36 -6.03 -0.31 4.33e-9 Menopause (age at onset); LIHC cis rs3857536 0.605 rs36040831 chr6:66876588 G/A cg07460842 chr6:66804631 NA -0.55 -8.37 -0.41 1.48e-15 Blood trace element (Cu levels); LIHC cis rs6674176 0.696 rs4448553 chr1:44411589 A/G cg12908607 chr1:44402522 ARTN -0.48 -8.24 -0.41 3.68e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3008870 1.000 rs2065001 chr1:67486509 C/G cg02640540 chr1:67518911 SLC35D1 0.45 6.02 0.31 4.6e-9 Lymphocyte percentage of white cells; LIHC cis rs2580764 0.566 rs2920878 chr2:55296415 C/T cg09592903 chr2:55203963 RTN4 0.63 11.58 0.53 2.24e-26 Mean platelet volume; LIHC cis rs4845459 0.967 rs4845453 chr1:152591953 C/G cg27206522 chr1:152595629 LCE3A -0.25 -5.86 -0.3 1.12e-8 Psoriasis; LIHC cis rs2066819 1.000 rs2695782 chr12:56722830 C/T cg26714650 chr12:56694279 CS 1.3 15.42 0.64 4.11e-41 Psoriasis vulgaris; LIHC cis rs798554 0.680 rs1713912 chr7:2895784 C/A cg04166393 chr7:2884313 GNA12 0.5 7.94 0.39 3.03e-14 Height; LIHC cis rs6570726 0.738 rs6917199 chr6:145918320 G/A cg13319975 chr6:146136371 FBXO30 -0.43 -6.72 -0.34 7.77e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.878 rs6748745 chr2:26364190 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.79 -9.81 -0.47 3.51e-20 Gut microbiome composition (summer); LIHC cis rs17376456 0.569 rs7713956 chr5:93133185 T/C cg25358565 chr5:93447407 FAM172A -0.79 -7.68 -0.38 1.74e-13 Diabetic retinopathy; LIHC cis rs12079745 0.793 rs3766082 chr1:169215068 A/T cg09363564 chr1:169337483 NME7;BLZF1 0.66 6.49 0.33 3.02e-10 QT interval; LIHC cis rs9811920 0.529 rs793442 chr3:99581062 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.49 6.9 0.35 2.46e-11 Axial length; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26815147 chr15:45879302 PLDN -0.51 -6.34 -0.32 7.29e-10 Systolic blood pressure; LIHC trans rs2727020 0.521 rs4980445 chr11:49570183 C/T cg03929089 chr4:120376271 NA -0.69 -10.17 -0.48 2.15e-21 Coronary artery disease; LIHC cis rs2625529 0.824 rs7170754 chr15:72218594 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.79 -0.3 1.63e-8 Red blood cell count; LIHC cis rs17106184 0.892 rs12090545 chr1:51193984 A/G cg07174182 chr1:51127561 FAF1 -0.62 -7.22 -0.36 3.38e-12 Type 2 diabetes; LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.1 0.4 9.76e-15 Height; LIHC cis rs7833790 0.660 rs1451995 chr8:82746123 G/C cg17211192 chr8:82754475 SNX16 0.58 10.54 0.5 1.16e-22 Diastolic blood pressure; LIHC cis rs10463316 0.862 rs59390562 chr5:150776092 A/G cg03212797 chr5:150827313 SLC36A1 -0.44 -6.71 -0.34 7.92e-11 Metabolite levels (Pyroglutamine); LIHC cis rs9522267 0.535 rs9522296 chr13:112234340 C/T cg10483660 chr13:112241077 NA 0.21 5.77 0.3 1.79e-8 Hepatitis; LIHC cis rs9303280 0.901 rs2313430 chr17:37929816 T/C cg11212589 chr17:38028394 ZPBP2 -0.34 -6.96 -0.35 1.74e-11 Self-reported allergy; LIHC cis rs644799 0.930 rs2186782 chr11:95649543 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.65 8.97 0.44 2.05e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg16405210 chr4:1374714 KIAA1530 -0.58 -8.55 -0.42 4.11e-16 Longevity; LIHC cis rs7095944 0.583 rs12218394 chr10:126480591 G/C cg08799069 chr10:126477246 METTL10 -0.4 -7.26 -0.37 2.7e-12 Asthma; LIHC cis rs8060686 0.641 rs9932251 chr16:68131732 G/A cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.69e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs6138458 0.717 rs2179732 chr20:25000446 A/T cg26195577 chr20:24973756 C20orf3 0.91 11.33 0.52 1.82e-25 Blood protein levels; LIHC cis rs7523273 0.606 rs12401619 chr1:207976276 G/C cg22525895 chr1:207977042 MIR29B2 -0.65 -10.41 -0.49 3.22e-22 Schizophrenia; LIHC cis rs4819052 0.851 rs7279011 chr21:46655995 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.69 10.28 0.49 9.2e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9303401 0.659 rs35928756 chr17:56702652 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs924607 0.931 rs1709556 chr5:637058 A/G cg04221910 chr5:616842 CEP72 0.41 7.29 0.37 2.19e-12 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01947930 chr5:141016379 RELL2;HDAC3 -0.43 -6.61 -0.34 1.51e-10 Pancreatic cancer; LIHC cis rs4253772 0.591 rs6519993 chr22:46656479 A/G cg09491104 chr22:46646882 C22orf40 -0.71 -8.35 -0.41 1.68e-15 LDL cholesterol;Cholesterol, total; LIHC cis rs875971 0.862 rs778736 chr7:65813848 C/T cg11764359 chr7:65958608 NA 0.77 13.41 0.59 3.06e-33 Aortic root size; LIHC cis rs986417 1.000 rs9989167 chr14:60942374 T/C cg27398547 chr14:60952738 C14orf39 0.81 9.39 0.45 8.69e-19 Gut microbiota (bacterial taxa); LIHC cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg04267008 chr7:1944627 MAD1L1 -0.54 -8.49 -0.42 6.54e-16 Bipolar disorder and schizophrenia; LIHC trans rs1147813 0.654 rs993232 chr9:25890597 A/G cg07359730 chr1:67896138 SERBP1 0.5 6.4 0.33 5.07e-10 Morning vs. evening chronotype; LIHC cis rs3096299 0.606 rs2965960 chr16:89541795 G/A cg06640241 chr16:89574553 SPG7 0.62 8.81 0.43 6.39e-17 Multiple myeloma (IgH translocation); LIHC cis rs1348850 0.632 rs13008833 chr2:178514439 G/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.57 7.71 0.38 1.42e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs801193 1.000 rs2003301 chr7:66147656 G/C cg11764359 chr7:65958608 NA -0.71 -10.74 -0.5 2.3e-23 Aortic root size; LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg06873352 chr17:61820015 STRADA 0.6 9.32 0.45 1.51e-18 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19487717 chr11:70263216 CTTN 0.49 6.93 0.35 2.17e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2470135 1 rs2470135 chr15:43995789 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.38 6.05 0.31 3.72e-9 Diastolic blood pressure; LIHC cis rs4728302 0.559 rs12707093 chr7:133200817 C/T cg10665199 chr7:133106180 EXOC4 0.52 8.14 0.4 7.57e-15 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs12479064 0.703 rs28382977 chr2:100018304 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.64 -8.04 -0.4 1.53e-14 Chronic sinus infection; LIHC cis rs763121 0.889 rs1837988 chr22:38901094 A/G cg14440974 chr22:39074834 NA -0.4 -6.26 -0.32 1.18e-9 Menopause (age at onset); LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg13152130 chr6:118910203 C6orf204 -0.62 -6.99 -0.35 1.49e-11 Diastolic blood pressure; LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg08219700 chr8:58056026 NA 0.52 7.14 0.36 5.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs17401966 0.838 rs4333852 chr1:10387704 A/T cg15208524 chr1:10270712 KIF1B -0.38 -5.88 -0.3 9.55e-9 Hepatocellular carcinoma; LIHC cis rs8177179 0.967 rs6439434 chr3:133450371 T/G cg24879335 chr3:133465180 TF 0.48 11.13 0.52 9.45e-25 Iron status biomarkers (transferrin levels); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01261044 chr14:35451962 SRP54 0.44 6.27 0.32 1.09e-9 Pancreatic cancer; LIHC cis rs523522 0.923 rs3916065 chr12:120934624 A/C cg12219531 chr12:120966889 COQ5 0.67 13.22 0.58 1.57e-32 High light scatter reticulocyte count; LIHC cis rs6430585 0.527 rs12467569 chr2:136413847 T/C cg07169764 chr2:136633963 MCM6 0.68 8.7 0.43 1.41e-16 Corneal structure; LIHC cis rs9790314 0.502 rs7647118 chr3:161016165 T/C cg17135325 chr3:160939158 NMD3 0.56 8.07 0.4 1.22e-14 Morning vs. evening chronotype; LIHC trans rs526821 0.595 rs608964 chr11:55339266 G/A cg15704280 chr7:45808275 SEPT13 -0.51 -7.79 -0.39 7.89e-14 Pediatric bone mineral density (spine); LIHC cis rs763121 0.853 rs5750633 chr22:38993467 A/G cg14440974 chr22:39074834 NA -0.36 -5.94 -0.31 7.11e-9 Menopause (age at onset); LIHC cis rs10256972 0.967 rs1881122 chr7:1040946 A/T cg16145915 chr7:1198662 ZFAND2A -0.29 -7.09 -0.36 7.62e-12 Longevity;Endometriosis; LIHC trans rs8033655 1.000 rs8033655 chr15:50308950 A/G cg10099229 chr12:6960622 USP5;CDCA3 0.42 6.09 0.31 3.1e-9 Skin pigmentation; LIHC cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg24209194 chr3:40518798 ZNF619 0.44 6.28 0.32 1.05e-9 Renal cell carcinoma; LIHC cis rs2070488 0.775 rs6794397 chr3:38559307 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.69 11.48 0.53 5.17e-26 Electrocardiographic conduction measures; LIHC cis rs9419702 0.526 rs9419637 chr10:133548059 T/C cg20568497 chr10:133558893 NA 0.41 6.17 0.32 1.88e-9 Survival in rectal cancer; LIHC cis rs2153535 0.580 rs962590 chr6:8450899 A/G cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC cis rs7503168 1.000 rs12604067 chr17:33952103 C/G cg20932281 chr17:33905541 PEX12 0.54 7.01 0.35 1.25e-11 Plateletcrit; LIHC cis rs7772486 0.692 rs2265915 chr6:146194332 A/T cg05347473 chr6:146136440 FBXO30 0.38 6.15 0.32 2.12e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg12516959 chr21:47718080 NA 0.36 5.85 0.3 1.17e-8 Testicular germ cell tumor; LIHC cis rs9814567 1.000 rs13322305 chr3:134310791 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.0 -0.54 6.29e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg24675879 chr17:28444056 MIR423;CCDC55 -0.55 -6.31 -0.32 8.83e-10 Bronchial neuroendocrine tumor; LIHC cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg16926213 chr1:1841314 NA 0.32 5.88 0.3 9.98e-9 Body mass index; LIHC cis rs4969178 0.600 rs4969183 chr17:76393372 A/G cg05887092 chr17:76393375 PGS1 0.34 6.54 0.33 2.22e-10 HDL cholesterol levels; LIHC cis rs7833986 0.501 rs72653951 chr8:56961837 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.73 7.88 0.39 4.51e-14 Height; LIHC cis rs11608355 0.545 rs11615949 chr12:109894347 G/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs929354 0.685 rs7807856 chr7:156934498 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.82 0.3 1.33e-8 Body mass index; LIHC cis rs17384381 0.636 rs11161615 chr1:85906816 A/G cg16011679 chr1:85725395 C1orf52 -0.49 -6.28 -0.32 9.99e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.01 -0.44 1.48e-17 Bipolar disorder; LIHC cis rs17253792 0.822 rs8006705 chr14:56171283 C/T cg01858014 chr14:56050164 KTN1 -0.62 -6.76 -0.34 6.02e-11 Putamen volume; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC cis rs744487 1.000 rs11581667 chr1:234726356 C/T cg09691134 chr1:234734475 NA 0.4 6.5 0.33 2.83e-10 LDL cholesterol; LIHC cis rs1577917 1.000 rs12204015 chr6:86598334 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -8.1 -0.4 9.48e-15 Response to antipsychotic treatment; LIHC cis rs1005277 0.541 rs1740741 chr10:38515334 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC trans rs729050 0.961 rs2148564 chr14:94073093 A/G cg00587042 chr7:42927968 NA -0.46 -6.06 -0.31 3.65e-9 Body mass index; LIHC cis rs208520 0.690 rs3899423 chr6:66835285 A/G cg07460842 chr6:66804631 NA -0.75 -8.43 -0.41 1e-15 Exhaled nitric oxide output; LIHC cis rs709400 0.628 rs6575984 chr14:103876454 A/G cg26031613 chr14:104095156 KLC1 -0.72 -9.56 -0.46 2.48e-19 Body mass index; LIHC cis rs3096299 0.967 rs2965932 chr16:89477051 C/T cg02187348 chr16:89574699 SPG7 -0.5 -7.28 -0.37 2.35e-12 Multiple myeloma (IgH translocation); LIHC cis rs12594515 1.000 rs8025258 chr15:45987554 C/A cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.69e-10 Waist circumference;Weight; LIHC cis rs12908161 1.000 rs11632465 chr15:85282045 A/T cg12863693 chr15:85201151 NMB 0.47 6.84 0.35 3.59e-11 Schizophrenia; LIHC cis rs8180040 0.966 rs12632132 chr3:47477019 C/T cg16586182 chr3:47516702 SCAP -0.58 -11.15 -0.52 7.83e-25 Colorectal cancer; LIHC cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.34 0.45 1.31e-18 Bipolar disorder; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg09455208 chr3:40491958 NA -0.38 -7.74 -0.39 1.15e-13 Renal cell carcinoma; LIHC cis rs11758351 1.000 rs41266807 chr6:26199822 A/G cg16070018 chr6:26224392 HIST1H3E 0.55 6.54 0.33 2.28e-10 Gout;Renal underexcretion gout; LIHC cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg05754148 chr16:3507555 NAT15 -0.38 -6.41 -0.33 4.94e-10 Tuberculosis; LIHC cis rs13161895 0.646 rs77997852 chr5:179504925 T/C cg06664874 chr5:179499304 RNF130 0.7 7.4 0.37 1.1e-12 LDL cholesterol; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg14465769 chr3:197021243 DLG1 -0.29 -6.24 -0.32 1.32e-9 Calcium levels; LIHC cis rs7647973 0.626 rs6809879 chr3:49834571 A/G cg03060546 chr3:49711283 APEH -0.59 -6.83 -0.35 3.83e-11 Menarche (age at onset); LIHC cis rs6459788 1.000 rs6459788 chr7:157260190 G/A cg06271696 chr7:157225062 NA -0.38 -6.73 -0.34 7.3e-11 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs6459788 0.585 rs6950818 chr7:157235364 C/G cg06271696 chr7:157225062 NA -0.55 -10.42 -0.49 2.96e-22 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs2073300 1.000 rs6114098 chr20:23444276 G/A cg12062639 chr20:23401060 NAPB 0.85 10.27 0.49 9.25e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4268898 1.000 rs6707781 chr2:24441883 T/G cg06627628 chr2:24431161 ITSN2 0.5 7.24 0.36 2.96e-12 Asthma; LIHC cis rs3741151 1.000 rs76764824 chr11:73073580 C/T cg17517138 chr11:73019481 ARHGEF17 0.9 6.51 0.33 2.74e-10 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs77633900 0.614 rs2439989 chr15:76883862 G/C cg21673338 chr15:77095150 SCAPER -0.5 -7.24 -0.36 2.93e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs2153535 0.580 rs2143356 chr6:8517675 C/T cg07606381 chr6:8435919 SLC35B3 0.8 11.77 0.54 4.4e-27 Motion sickness; LIHC cis rs9916302 0.904 rs11078898 chr17:37536480 A/G cg00129232 chr17:37814104 STARD3 0.39 6.27 0.32 1.11e-9 Glomerular filtration rate (creatinine); LIHC cis rs17401966 1.000 rs7520935 chr1:10354271 G/T cg19773385 chr1:10388646 KIF1B -0.48 -8.4 -0.41 1.18e-15 Hepatocellular carcinoma; LIHC cis rs4742903 0.935 rs7872170 chr9:106957103 G/A cg14250997 chr9:106856677 SMC2 0.36 6.07 0.31 3.36e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs9443189 0.950 rs6453845 chr6:76576527 G/T cg01950844 chr6:76311363 SENP6 -0.52 -6.71 -0.34 8.18e-11 Prostate cancer; LIHC cis rs8062405 0.679 rs72793818 chr16:28893137 G/A cg00204512 chr16:28754710 NA 0.34 6.3 0.32 9.02e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2180341 1.000 rs7453272 chr6:127633959 C/T cg24812749 chr6:127587940 RNF146 -0.97 -13.89 -0.6 4.16e-35 Breast cancer; LIHC cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg16405210 chr4:1374714 KIAA1530 -0.56 -8.19 -0.4 5.24e-15 Longevity; LIHC cis rs6860806 0.661 rs4705929 chr5:131584178 G/T cg24060327 chr5:131705240 SLC22A5 -0.44 -5.73 -0.3 2.18e-8 Breast cancer; LIHC cis rs344364 0.511 rs1742462 chr16:1946062 A/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.57 -7.56 -0.38 3.78e-13 Glomerular filtration rate in chronic kidney disease; LIHC cis rs1712517 0.844 rs1163081 chr10:105029840 G/C cg05636881 chr10:105038444 INA 0.38 5.91 0.3 8.15e-9 Migraine; LIHC cis rs4919087 0.748 rs793517 chr10:98987522 A/G cg25902810 chr10:99078978 FRAT1 -0.53 -6.1 -0.31 2.92e-9 Monocyte count; LIHC cis rs116095464 0.558 rs7710005 chr5:233572 A/G cg22857025 chr5:266934 NA -1.48 -18.11 -0.7 6.78e-52 Breast cancer; LIHC cis rs2304069 0.826 rs184960 chr5:149343370 C/T cg12661370 chr5:149340060 SLC26A2 -0.54 -7.35 -0.37 1.43e-12 HIV-1 control; LIHC trans rs17685 0.753 rs10476 chr7:75696420 C/T cg19862616 chr7:65841803 NCRNA00174 -0.93 -19.59 -0.73 8e-58 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6502050 0.835 rs67149434 chr17:80128007 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs9902453 0.967 rs9913074 chr17:28481199 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.03 0.44 1.27e-17 Coffee consumption (cups per day); LIHC trans rs11098499 0.863 rs3775854 chr4:120471971 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.36 0.45 1.08e-18 Corneal astigmatism; LIHC cis rs2386661 0.547 rs4747358 chr10:5650193 A/G cg17085576 chr10:5658249 NA 0.35 6.21 0.32 1.55e-9 Breast cancer; LIHC cis rs7914558 0.966 rs7085598 chr10:104650128 T/C cg15744005 chr10:104629667 AS3MT -0.41 -9.3 -0.45 1.75e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9911578 0.934 rs58092632 chr17:57111101 T/C cg05425664 chr17:57184151 TRIM37 0.59 8.76 0.43 9.33e-17 Intelligence (multi-trait analysis); LIHC cis rs62179067 0.708 rs77046457 chr2:179940751 C/T cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs11711311 0.712 rs2271498 chr3:113334752 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.32 -5.85 -0.3 1.15e-8 IgG glycosylation; LIHC cis rs12893668 0.645 rs35229468 chr14:104052057 C/T cg24130564 chr14:104152367 KLC1 -0.54 -8.7 -0.43 1.44e-16 Reticulocyte count; LIHC cis rs911119 0.955 rs7265178 chr20:23603382 C/G cg16589663 chr20:23618590 CST3 0.75 7.88 0.39 4.28e-14 Chronic kidney disease; LIHC cis rs11585357 0.895 rs72633812 chr1:17623140 T/C cg08277548 chr1:17600880 PADI3 -0.65 -6.85 -0.35 3.5e-11 Hair shape; LIHC cis rs7552404 0.960 rs12134854 chr1:76137606 A/G cg10523679 chr1:76189770 ACADM 0.6 8.39 0.41 1.28e-15 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2463822 1.000 rs2463820 chr11:62112290 A/T cg06239285 chr11:62104954 ASRGL1 0.97 7.09 0.36 7.81e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs25645 0.830 rs3935281 chr17:38188419 C/T cg17467752 chr17:38218738 THRA -0.54 -9.18 -0.44 4.27e-18 Myeloid white cell count; LIHC cis rs3749237 0.595 rs2878298 chr3:49406080 T/C cg03060546 chr3:49711283 APEH 0.58 9.47 0.46 4.75e-19 Resting heart rate; LIHC cis rs2635047 0.967 rs2684843 chr18:44726260 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.49 6.65 0.34 1.13e-10 Educational attainment; LIHC cis rs35146811 0.883 rs4134903 chr7:99711040 G/A cg22906224 chr7:99728672 NA 0.43 5.98 0.31 5.51e-9 Coronary artery disease; LIHC cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -11.17 -0.52 6.65e-25 Platelet count; LIHC cis rs818427 0.964 rs495794 chr5:112201094 A/G cg07820702 chr5:112228657 REEP5 0.36 5.79 0.3 1.62e-8 Total body bone mineral density; LIHC cis rs1538970 0.962 rs2185549 chr1:45814103 C/T cg05343316 chr1:45956843 TESK2 -0.59 -8.82 -0.43 5.83e-17 Platelet count; LIHC cis rs4242434 0.819 rs6558173 chr8:22492103 A/C cg14690197 chr8:22456421 C8orf58 -0.36 -5.76 -0.3 1.89e-8 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs8064299 0.967 rs3744208 chr17:72767565 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.7 11.87 0.54 1.97e-27 Monocyte count; LIHC cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg21016266 chr12:122356598 WDR66 0.39 5.86 0.3 1.11e-8 Mean corpuscular volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21850239 chr11:62528988 POLR2G 0.5 6.32 0.32 8.38e-10 Lung function (FEV1/FVC); LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg08935602 chr16:2509817 C16orf59 0.34 6.14 0.32 2.23e-9 Metabolic traits; LIHC trans rs2243480 0.831 rs7806717 chr7:65393174 A/G cg10756647 chr7:56101905 PSPH -1.09 -13.61 -0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg16405210 chr4:1374714 KIAA1530 -0.46 -7.0 -0.35 1.36e-11 Obesity-related traits; LIHC trans rs10242455 0.571 rs45593341 chr7:99304911 C/A cg09045935 chr12:6379348 NA 0.73 6.13 0.31 2.43e-9 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26614578 chr12:113623930 C12orf52;DDX54 0.53 7.73 0.39 1.19e-13 Pancreatic cancer; LIHC cis rs6430585 0.583 rs2304370 chr2:136561735 G/A cg07169764 chr2:136633963 MCM6 1.12 17.17 0.68 4.25e-48 Corneal structure; LIHC cis rs208520 0.690 rs207107 chr6:66794385 T/C cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC cis rs7572733 0.534 rs1435568 chr2:198762879 T/C cg03934865 chr2:198174659 NA 0.47 6.74 0.34 6.87e-11 Dermatomyositis; LIHC cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.91 8.42 0.41 1.01e-15 Platelet count; LIHC cis rs2842992 0.789 rs2295901 chr6:160201295 C/A cg19482086 chr6:160211437 TCP1;MRPL18 0.68 12.22 0.55 9.59e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg03517284 chr6:25882590 NA -0.42 -6.51 -0.33 2.7e-10 Height; LIHC cis rs8067545 0.611 rs12949481 chr17:20190974 C/A cg13482628 chr17:19912719 NA -0.42 -6.81 -0.35 4.33e-11 Schizophrenia; LIHC cis rs1577917 0.710 rs1059306 chr6:86388109 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.68 13.24 0.58 1.39e-32 Response to antipsychotic treatment; LIHC cis rs6442522 0.640 rs28632773 chr3:15515918 C/G cg16303742 chr3:15540471 COLQ 0.4 6.55 0.33 2.06e-10 Uric acid levels; LIHC cis rs8067354 0.831 rs2333617 chr17:57896220 T/A cg13753209 chr17:57696993 CLTC -0.59 -8.95 -0.44 2.27e-17 Hemoglobin concentration; LIHC cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg09455208 chr3:40491958 NA 0.38 7.63 0.38 2.34e-13 Renal cell carcinoma; LIHC cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg22633049 chr21:46681294 NA -0.37 -6.39 -0.33 5.3e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7772486 0.875 rs1331640 chr6:146427250 G/A cg23711669 chr6:146136114 FBXO30 0.65 10.74 0.5 2.24e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs13191362 1.000 rs55822577 chr6:163069710 G/A cg14584255 chr6:163149320 PACRG;PARK2 0.64 5.74 0.3 2.11e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2408955 0.501 rs8716 chr12:48539482 T/G cg21466736 chr12:48725269 NA -0.63 -9.18 -0.44 4.2e-18 Glycated hemoglobin levels; LIHC cis rs7412746 0.611 rs9661876 chr1:150910911 C/T cg15448220 chr1:150897856 SETDB1 0.39 6.25 0.32 1.22e-9 Melanoma; LIHC cis rs7395581 0.959 rs7129661 chr11:47268550 T/G cg25783544 chr11:47291846 MADD 0.43 6.34 0.32 7.24e-10 HDL cholesterol; LIHC cis rs7100689 0.556 rs10788541 chr10:82016530 T/G cg01528321 chr10:82214614 TSPAN14 0.78 10.31 0.49 7.09e-22 Post bronchodilator FEV1; LIHC cis rs116095464 0.558 rs6866632 chr5:264429 C/G cg22857025 chr5:266934 NA -1.51 -17.84 -0.69 8.44e-51 Breast cancer; LIHC trans rs1864585 0.520 rs73200724 chr8:10592331 G/T cg26278703 chr11:58910052 FAM111A 0.74 6.46 0.33 3.56e-10 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs34172651 0.876 rs1862451 chr16:24803620 A/G cg00152838 chr16:24741724 TNRC6A -0.5 -6.7 -0.34 8.48e-11 Intelligence (multi-trait analysis); LIHC cis rs1023500 0.573 rs133380 chr22:42468910 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.36 -7.14 -0.36 5.68e-12 Schizophrenia; LIHC cis rs8180040 0.577 rs12493425 chr3:47176946 T/G cg27129171 chr3:47204927 SETD2 0.58 9.68 0.46 9.8e-20 Colorectal cancer; LIHC cis rs760762 0.636 rs6065332 chr20:39946922 C/G cg06424997 chr20:39929561 ZHX3 0.36 5.93 0.31 7.22e-9 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; LIHC cis rs1881396 0.531 rs72613829 chr2:27902987 C/T cg27432699 chr2:27873401 GPN1 0.47 6.66 0.34 1.1e-10 Nonalcoholic fatty liver disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19514765 chr6:27805693 HIST1H2BN;HIST1H2AK 0.42 6.18 0.32 1.81e-9 Cognitive function; LIHC cis rs55665837 0.701 rs11023265 chr11:14616038 C/T cg19336497 chr11:14380999 RRAS2 -0.37 -6.16 -0.32 2.03e-9 Vitamin D levels; LIHC cis rs6964587 1.000 rs1859114 chr7:91682848 T/C cg17063962 chr7:91808500 NA 1.02 19.57 0.73 9.42e-58 Breast cancer; LIHC cis rs2273156 1.000 rs56686328 chr14:35458070 G/A cg16230307 chr14:35515116 FAM177A1 -0.41 -6.04 -0.31 3.96e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs2795502 1.000 rs1581702 chr10:43344246 G/A cg27426351 chr10:43362370 NA 0.46 5.82 0.3 1.38e-8 Blood protein levels; LIHC trans rs2727020 0.554 rs2866490 chr11:49425463 A/G cg15704280 chr7:45808275 SEPT13 -0.76 -11.3 -0.52 2.34e-25 Coronary artery disease; LIHC cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg11644478 chr21:40555479 PSMG1 0.84 10.53 0.49 1.18e-22 Cognitive function; LIHC cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg00684032 chr4:1343700 KIAA1530 0.4 6.81 0.35 4.42e-11 Obesity-related traits; LIHC cis rs17001868 0.568 rs909669 chr22:40742417 C/T cg07138101 chr22:40742427 ADSL 0.55 6.46 0.33 3.62e-10 Mammographic density (dense area); LIHC cis rs35146811 0.844 rs4729576 chr7:99692594 G/A cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.42 5.99 0.31 5.4e-9 Coronary artery disease; LIHC cis rs55665837 1.000 rs3923294 chr11:14441402 T/G cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs10508774 1.000 rs11008970 chr10:32835635 A/G cg01819863 chr10:32635814 EPC1 0.65 6.06 0.31 3.66e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7044106 0.762 rs10760110 chr9:123412563 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.52 -8.05 -0.4 1.39e-14 Hip circumference adjusted for BMI; LIHC cis rs11785400 1.000 rs7459630 chr8:143738585 A/C cg10596483 chr8:143751796 JRK 0.52 8.46 0.42 7.74e-16 Schizophrenia; LIHC cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg22105103 chr4:187893119 NA 0.35 8.98 0.44 1.81e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769765 0.730 rs62233964 chr22:50317410 C/G cg02269571 chr22:50332266 NA -0.66 -8.9 -0.43 3.32e-17 Schizophrenia; LIHC cis rs908922 0.847 rs499697 chr1:152493154 A/G cg20991723 chr1:152506922 NA -0.4 -6.35 -0.32 6.72e-10 Hair morphology; LIHC cis rs1559088 0.600 rs7256470 chr19:33558085 C/A cg27124370 chr19:33622961 WDR88 0.55 7.93 0.39 3.2e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2991971 0.810 rs998199 chr1:45912898 A/C cg24296786 chr1:45957014 TESK2 -0.54 -8.34 -0.41 1.9e-15 High light scatter reticulocyte count; LIHC cis rs908922 0.676 rs4240887 chr1:152530510 C/T cg20991723 chr1:152506922 NA -0.52 -8.83 -0.43 5.63e-17 Hair morphology; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg14709524 chr16:89940631 TCF25 0.5 6.53 0.33 2.36e-10 Skin colour saturation; LIHC cis rs1728785 0.892 rs4783648 chr16:68558334 C/T cg02972257 chr16:68554789 NA 0.6 6.2 0.32 1.62e-9 Ulcerative colitis; LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg15664640 chr17:80829946 TBCD -0.37 -5.9 -0.3 8.91e-9 Glycated hemoglobin levels; LIHC cis rs68170813 0.523 rs12154285 chr7:106993573 G/A cg02696742 chr7:106810147 HBP1 -0.5 -5.83 -0.3 1.29e-8 Coronary artery disease; LIHC cis rs78062588 1.000 rs61300392 chr1:154575685 A/T cg24304309 chr1:154577895 ADAR -0.51 -5.87 -0.3 1.01e-8 Lung cancer; LIHC cis rs2842992 0.830 rs1853259 chr6:160147441 A/G cg19482086 chr6:160211437 TCP1;MRPL18 -0.7 -12.3 -0.55 4.96e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs2292030 1 rs2292030 chr5:132161294 G/A cg02081065 chr5:132209139 LEAP2 0.28 5.77 0.3 1.81e-8 Apolipoprotein A-IV levels; LIHC cis rs896854 0.902 rs726816 chr8:95968413 T/G cg13393036 chr8:95962371 TP53INP1 -0.4 -9.04 -0.44 1.15e-17 Type 2 diabetes; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg20607798 chr8:58055168 NA 0.7 8.53 0.42 4.82e-16 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs10510708 chr3:40404770 A/G cg13409248 chr3:40428643 ENTPD3 0.4 6.55 0.33 2.12e-10 Renal cell carcinoma; LIHC cis rs9291683 0.632 rs13101785 chr4:10042915 T/A cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.78e-13 Bone mineral density; LIHC cis rs9611565 0.921 rs4822021 chr22:41726053 G/A cg03806693 chr22:41940476 POLR3H -0.82 -9.66 -0.46 1.13e-19 Vitiligo; LIHC cis rs9388451 0.839 rs9321054 chr6:126079968 A/G cg06289844 chr6:126071538 HEY2 -0.35 -6.14 -0.31 2.35e-9 Brugada syndrome; LIHC cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg06640241 chr16:89574553 SPG7 0.84 15.6 0.64 8.46e-42 Multiple myeloma (IgH translocation); LIHC cis rs7917772 0.503 rs10883732 chr10:104293461 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.05 0.58 7.17e-32 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs780094 0.585 rs7586601 chr2:27584666 A/G cg21747090 chr2:27597821 SNX17 -0.43 -6.32 -0.32 8.18e-10 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg18538332 chr22:24372958 LOC391322 -0.54 -7.6 -0.38 2.79e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs1814175 0.817 rs4881627 chr11:49953955 C/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs858239 0.600 rs6961131 chr7:23134790 A/G cg23682824 chr7:23144976 KLHL7 0.46 6.95 0.35 1.89e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2304069 0.526 rs6863283 chr5:149402448 C/A cg12661370 chr5:149340060 SLC26A2 0.54 8.06 0.4 1.34e-14 HIV-1 control; LIHC cis rs875971 0.862 rs1695820 chr7:65844563 G/A cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21607453 chr9:98783545 NCRNA00092 0.39 6.47 0.33 3.3e-10 Pancreatic cancer; LIHC cis rs10751667 0.643 rs6597969 chr11:928843 C/T cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.49 0.46 4.14e-19 Electroencephalogram traits; LIHC cis rs13223928 0.631 rs12531881 chr7:3156842 C/T cg19214707 chr7:3157722 NA -0.34 -5.97 -0.31 5.9e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs35883536 0.609 rs1577513 chr1:101044402 C/A cg14515779 chr1:101123966 NA -0.49 -7.03 -0.36 1.16e-11 Monocyte count; LIHC cis rs1577917 0.958 rs12192033 chr6:86472559 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.27 -0.41 3.06e-15 Response to antipsychotic treatment; LIHC cis rs17826219 0.706 rs73271850 chr17:29142140 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Body mass index; LIHC cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg13395646 chr4:1353034 KIAA1530 -0.43 -6.05 -0.31 3.76e-9 Longevity; LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg00656387 chr3:40428638 ENTPD3 0.5 8.52 0.42 5.28e-16 Renal cell carcinoma; LIHC cis rs950027 1.000 rs950027 chr15:45801035 C/T cg26924012 chr15:45694286 SPATA5L1 -0.47 -6.58 -0.34 1.8e-10 Response to fenofibrate (adiponectin levels); LIHC cis rs12478296 0.591 rs7573042 chr2:242996589 A/G cg06360820 chr2:242988706 NA -0.72 -11.29 -0.52 2.43e-25 Obesity-related traits; LIHC cis rs5769707 0.667 rs4824069 chr22:50030325 T/C cg07959070 chr22:50026188 C22orf34 -0.34 -8.4 -0.41 1.22e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9303280 0.806 rs10445308 chr17:37938047 C/T cg00129232 chr17:37814104 STARD3 -0.35 -5.74 -0.3 2.07e-8 Self-reported allergy; LIHC cis rs2404618 0.534 rs2214861 chr8:1490604 A/G cg13402656 chr8:1511478 DLGAP2 -0.54 -11.11 -0.51 1.1e-24 Lung cancer; LIHC trans rs1814175 0.615 rs7113020 chr11:49746540 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.06 0.36 9.47e-12 Height; LIHC cis rs922107 1.000 rs922107 chr1:90022796 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.82 -0.39 6.62e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs6960043 0.738 rs7798360 chr7:15055972 A/G cg19272540 chr7:15055459 NA 0.25 6.74 0.34 6.88e-11 Type 2 diabetes; LIHC cis rs7535752 0.519 rs11583012 chr1:8440132 G/A cg20416874 chr1:8611966 RERE 0.5 5.93 0.31 7.5e-9 Breast cancer; LIHC trans rs1728785 0.818 rs12926059 chr16:68569459 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.49 6.11 0.31 2.65e-9 Ulcerative colitis; LIHC cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg12310025 chr6:25882481 NA -0.66 -9.5 -0.46 3.88e-19 Blood metabolite levels; LIHC cis rs344364 0.529 rs186941 chr16:1930088 T/C cg26897989 chr16:1907736 C16orf73 0.5 6.04 0.31 4.02e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs7772486 0.875 rs2492855 chr6:146296926 A/G cg23711669 chr6:146136114 FBXO30 0.59 10.3 0.49 7.75e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2404602 0.716 rs12441247 chr15:76812316 T/C cg23625390 chr15:77176239 SCAPER 0.37 6.01 0.31 4.81e-9 Blood metabolite levels; LIHC cis rs28829049 0.597 rs2296107 chr1:19476649 C/G cg13387374 chr1:19411106 UBR4 0.4 6.41 0.33 4.8e-10 QRS duration in Tripanosoma cruzi seropositivity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15130565 chr3:61546275 PTPRG 0.41 6.15 0.32 2.21e-9 Pancreatic cancer; LIHC cis rs11098499 0.818 rs10008791 chr4:120431469 A/C cg09307838 chr4:120376055 NA 0.77 11.95 0.54 9.51e-28 Corneal astigmatism; LIHC cis rs1538970 0.962 rs2153608 chr1:45813941 C/T cg24296786 chr1:45957014 TESK2 0.5 7.47 0.37 6.63e-13 Platelet count; LIHC cis rs4555082 0.957 rs2816609 chr14:105720803 A/C cg13114125 chr14:105738426 BRF1 -0.76 -10.14 -0.48 2.69e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs11122272 0.701 rs2790894 chr1:231505587 T/A cg06096015 chr1:231504339 EGLN1 0.5 9.46 0.46 5.31e-19 Hemoglobin concentration; LIHC cis rs2361710 0.704 rs12937349 chr17:78120320 G/C cg09238746 chr17:78121135 EIF4A3 -0.54 -8.2 -0.41 5.07e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; LIHC cis rs7208859 0.673 rs73277986 chr17:29196197 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12594515 0.967 rs11070466 chr15:45984955 C/T cg01629716 chr15:45996671 NA 0.52 9.56 0.46 2.42e-19 Waist circumference;Weight; LIHC cis rs7107174 1.000 rs7117238 chr11:78040259 G/A cg02023728 chr11:77925099 USP35 0.46 9.02 0.44 1.4e-17 Testicular germ cell tumor; LIHC cis rs12971120 1.000 rs2278161 chr18:72176083 T/C cg25817165 chr18:72167213 CNDP2 -0.71 -12.54 -0.56 5.96e-30 Refractive error; LIHC cis rs7044106 0.791 rs10985001 chr9:123484232 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.73 0.39 1.23e-13 Hip circumference adjusted for BMI; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg01238044 chr22:24384105 GSTT1 -0.48 -6.64 -0.34 1.24e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg07234388 chr1:156261841 TMEM79 0.51 9.26 0.45 2.32e-18 Tonsillectomy; LIHC cis rs9921222 0.500 rs11645742 chr16:367516 C/T cg00101154 chr16:420108 MRPL28 -0.61 -8.41 -0.41 1.15e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs17685 0.632 rs1859793 chr7:75821283 G/A cg01364799 chr7:75623366 TMEM120A -0.41 -6.19 -0.32 1.7e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8016982 0.674 rs1957549 chr14:81706179 G/A cg01989461 chr14:81687754 GTF2A1 0.73 14.82 0.63 9.9e-39 Schizophrenia; LIHC cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2153535 0.601 rs1855768 chr6:8472969 T/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs9611565 0.512 rs2899349 chr22:42164660 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.31 0.49 7.06e-22 Vitiligo; LIHC cis rs9896933 0.723 rs7224189 chr17:80782227 C/T cg20578329 chr17:80767326 TBCD -0.64 -6.52 -0.33 2.54e-10 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.86 0.8 1.15e-78 Prudent dietary pattern; LIHC cis rs829883 0.664 rs829874 chr12:98840615 G/A cg25150519 chr12:98850993 NA 0.68 10.72 0.5 2.61e-23 Colorectal adenoma (advanced); LIHC cis rs12220238 1.000 rs11000902 chr10:75920483 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.71 6.63 0.34 1.34e-10 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03888365 chr8:123792680 ZHX2 0.44 6.26 0.32 1.15e-9 Pancreatic cancer; LIHC cis rs2933343 0.649 rs789219 chr3:128592520 G/A cg24203234 chr3:128598194 ACAD9 0.44 6.19 0.32 1.77e-9 IgG glycosylation; LIHC cis rs903552 0.800 rs1587107 chr15:102006485 T/C cg25677261 chr15:102009856 PCSK6 -0.5 -6.65 -0.34 1.14e-10 Diabetic kidney disease; LIHC trans rs1912702 0.592 rs4644672 chr11:79174777 A/G cg18020480 chr1:174186816 RABGAP1L 0.45 6.21 0.32 1.5e-9 Hair greying; LIHC cis rs727563 0.593 rs132770 chr22:42017264 A/G cg06634786 chr22:41940651 POLR3H 0.72 7.44 0.37 8.16e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg03806693 chr22:41940476 POLR3H 0.98 10.47 0.49 1.98e-22 Crohn's disease;Inflammatory bowel disease; LIHC trans rs6951245 0.529 rs10262070 chr7:1141738 C/T cg13565492 chr6:43139072 SRF -0.8 -7.45 -0.37 7.84e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs28374715 0.662 rs72737792 chr15:41515589 G/C cg18705301 chr15:41695430 NDUFAF1 -0.85 -9.57 -0.46 2.24e-19 Ulcerative colitis; LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg16358155 chr3:195490169 MUC4 0.42 6.34 0.32 7.24e-10 Lung disease severity in cystic fibrosis; LIHC trans rs1005277 0.579 rs2474567 chr10:38382492 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7727544 0.684 rs272889 chr5:131665378 A/G cg24060327 chr5:131705240 SLC22A5 -0.62 -9.15 -0.44 5.43e-18 Blood metabolite levels; LIHC cis rs9929218 0.954 rs4485355 chr16:68754730 C/T cg01231543 chr16:68741748 NA 0.38 6.17 0.32 1.97e-9 Colorectal cancer; LIHC cis rs1790761 0.667 rs591434 chr11:67337814 C/T cg00290607 chr11:67383545 NA 0.38 5.77 0.3 1.77e-8 Mean corpuscular volume; LIHC cis rs2120019 1.000 rs7173833 chr15:75369618 C/T cg11632617 chr15:75315747 PPCDC -0.43 -6.34 -0.32 7.35e-10 Blood trace element (Zn levels); LIHC cis rs9399135 0.967 rs4896120 chr6:135293512 C/G cg24558204 chr6:135376177 HBS1L 0.39 6.45 0.33 3.74e-10 Red blood cell count; LIHC cis rs5769765 0.913 rs2319462 chr22:50263370 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg14159672 chr1:205819179 PM20D1 0.7 10.06 0.48 4.86e-21 Menarche (age at onset); LIHC cis rs611744 0.781 rs75534351 chr8:109118714 A/T cg21045802 chr8:109455806 TTC35 0.5 8.44 0.42 9.1e-16 Dupuytren's disease; LIHC cis rs9322193 0.566 rs3922947 chr6:150245992 G/A cg01145232 chr6:150245071 RAET1G -0.42 -7.94 -0.39 2.93e-14 Lung cancer; LIHC cis rs7727544 0.735 rs4705933 chr5:131678412 G/A cg24060327 chr5:131705240 SLC22A5 -0.56 -8.08 -0.4 1.14e-14 Blood metabolite levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02464098 chr8:26240309 BNIP3L -0.53 -6.52 -0.33 2.56e-10 Systolic blood pressure; LIHC cis rs2204008 0.720 rs11180923 chr12:38255172 A/T cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.57e-21 Bladder cancer; LIHC cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.47 6.58 0.34 1.8e-10 Schizophrenia; LIHC trans rs1814175 0.565 rs4881721 chr11:49761851 G/A cg18944383 chr4:111397179 ENPEP 0.24 6.28 0.32 1.02e-9 Height; LIHC cis rs6424115 0.708 rs11803575 chr1:24182348 A/T cg08896387 chr1:24191740 FUCA1 0.37 6.02 0.31 4.39e-9 Immature fraction of reticulocytes; LIHC cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg23172400 chr8:95962367 TP53INP1 -0.35 -7.99 -0.4 2.02e-14 Type 2 diabetes; LIHC cis rs477692 0.870 rs512655 chr10:131424547 T/A cg05714579 chr10:131428358 MGMT 0.49 8.38 0.41 1.37e-15 Response to temozolomide; LIHC cis rs4073582 0.595 rs3016319 chr11:65981846 C/T cg16950941 chr11:66035639 RAB1B 0.59 8.88 0.43 3.75e-17 Gout; LIHC cis rs943466 1.000 rs61662306 chr6:33746697 G/A cg25922239 chr6:33757077 LEMD2 -0.47 -5.77 -0.3 1.75e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs57221529 0.766 rs56350081 chr5:583198 G/A cg09021430 chr5:549028 NA -0.44 -8.65 -0.42 1.97e-16 Lung disease severity in cystic fibrosis; LIHC cis rs35146811 0.622 rs6946204 chr7:99589125 T/C cg19636519 chr7:99541626 NA 0.3 5.74 0.3 2.07e-8 Coronary artery disease; LIHC cis rs1865721 0.839 rs59718187 chr18:73144032 C/T cg26385618 chr18:73139727 C18orf62 -0.31 -8.01 -0.4 1.85e-14 Intelligence; LIHC cis rs7937890 0.684 rs12799007 chr11:14426484 T/A cg02251663 chr11:14281053 SPON1 -0.43 -5.71 -0.3 2.45e-8 Mitochondrial DNA levels; LIHC cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg12751644 chr20:60527061 NA -0.35 -5.87 -0.3 1.03e-8 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12958836 chr12:8185024 FOXJ2 0.46 6.91 0.35 2.32e-11 Lung function (FEV1/FVC); LIHC cis rs703842 1.000 rs10877012 chr12:58162085 G/T cg04478727 chr12:58166393 METTL1;FAM119B 0.86 13.98 0.6 1.85e-35 Multiple sclerosis; LIHC cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.79 0.3 1.59e-8 Schizophrenia; LIHC cis rs240764 0.658 rs11155618 chr6:101181811 C/T cg09795085 chr6:101329169 ASCC3 -0.45 -6.59 -0.34 1.66e-10 Neuroticism; LIHC cis rs12971120 0.947 rs4891559 chr18:72170397 C/T cg26446133 chr18:72167187 CNDP2 -0.79 -15.91 -0.65 4.7e-43 Refractive error; LIHC cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg07061783 chr6:25882402 NA -0.47 -6.53 -0.33 2.38e-10 Blood metabolite levels; LIHC cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg00204748 chr12:29376779 FAR2 0.44 8.15 0.4 6.89e-15 QT interval; LIHC cis rs826838 1.000 rs11183160 chr12:38676702 T/C cg26384229 chr12:38710491 ALG10B 1.08 14.71 0.62 2.81e-38 Heart rate; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg20332866 chr1:100678932 DBT 0.39 6.75 0.34 6.34e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs738322 0.967 rs2092180 chr22:38571563 A/G cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs7617480 0.616 rs7429596 chr3:48808531 T/C cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.28 0.32 1.03e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs801193 0.967 rs2420827 chr7:66147101 G/A cg18876405 chr7:65276391 NA -0.4 -6.76 -0.34 5.92e-11 Aortic root size; LIHC cis rs3736594 0.802 rs9678824 chr2:27964328 G/C cg27432699 chr2:27873401 GPN1 0.42 6.53 0.33 2.42e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs1461503 0.934 rs7113330 chr11:122843358 C/T cg14473756 chr11:122847823 NA -0.32 -5.75 -0.3 1.98e-8 Menarche (age at onset); LIHC cis rs3796352 1.000 rs36090694 chr3:53010742 T/C cg07884673 chr3:53033167 SFMBT1 0.93 6.59 0.34 1.7e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg07308232 chr7:1071921 C7orf50 0.49 8.01 0.4 1.87e-14 Longevity;Endometriosis; LIHC cis rs644799 1.000 rs1784135 chr11:95531748 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6964587 1.000 rs6968870 chr7:91661111 G/C cg17063962 chr7:91808500 NA 1.01 18.6 0.71 7.45e-54 Breast cancer; LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg22903471 chr2:27725779 GCKR -0.46 -7.85 -0.39 5.35e-14 Menopause (age at onset); LIHC cis rs12478296 0.685 rs67829386 chr2:242992276 T/A cg06360820 chr2:242988706 NA -0.84 -12.87 -0.57 3.59e-31 Obesity-related traits; LIHC cis rs6456156 0.586 rs12525855 chr6:167480013 T/G cg07741184 chr6:167504864 NA 0.29 6.8 0.35 4.61e-11 Primary biliary cholangitis; LIHC cis rs600806 0.778 rs2115787 chr1:110003840 T/G cg16275483 chr1:110013120 SYPL2 -0.51 -6.33 -0.32 7.5e-10 Intelligence (multi-trait analysis); LIHC cis rs600806 0.888 rs3879449 chr1:109904971 A/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26476595 chr16:2284284 E4F1 0.48 6.7 0.34 8.8e-11 Hepatitis; LIHC cis rs703842 0.616 rs871871 chr12:58219681 G/A cg18357645 chr12:58087776 OS9 -0.42 -6.12 -0.31 2.62e-9 Multiple sclerosis; LIHC cis rs911119 0.955 rs8121283 chr20:23605002 G/C cg16589663 chr20:23618590 CST3 0.76 8.04 0.4 1.44e-14 Chronic kidney disease; LIHC cis rs7296418 0.699 rs11608297 chr12:123826642 T/C cg05973401 chr12:123451056 ABCB9 0.41 6.28 0.32 1.02e-9 Platelet count; LIHC cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.58 -0.34 1.76e-10 Gut microbiome composition (summer); LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg21747090 chr2:27597821 SNX17 -0.46 -6.99 -0.35 1.42e-11 Total body bone mineral density; LIHC cis rs7617773 0.707 rs13061269 chr3:48373343 C/T cg11946769 chr3:48343235 NME6 0.92 11.74 0.54 5.69e-27 Coronary artery disease; LIHC cis rs2176862 1.000 rs116786372 chr3:46610126 C/G cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.34 -0.32 7.42e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs875971 0.502 rs2465121 chr7:65621004 A/G cg02869306 chr7:64672164 INTS4L1 0.28 5.71 0.3 2.42e-8 Aortic root size; LIHC cis rs4919087 0.715 rs1253387 chr10:99032968 G/A cg25902810 chr10:99078978 FRAT1 -0.6 -6.85 -0.35 3.38e-11 Monocyte count; LIHC cis rs11785693 0.862 rs11774099 chr8:4988218 C/T cg26367366 chr8:4980734 NA 0.58 6.37 0.33 6.07e-10 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs10479542 1.000 rs10479542 chr5:178981241 T/A cg19723775 chr5:179050963 HNRNPH1 0.38 6.07 0.31 3.49e-9 Lung cancer; LIHC cis rs8010715 0.816 rs6573573 chr14:24599257 T/C cg23112188 chr14:24563095 PCK2 -0.29 -6.13 -0.31 2.38e-9 IgG glycosylation; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.09 -0.31 3.09e-9 Total body bone mineral density; LIHC cis rs17685 0.753 rs869804 chr7:75688954 A/G cg04610667 chr7:75704037 NA -0.35 -6.35 -0.32 6.75e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 12.98 0.57 1.39e-31 Platelet count; LIHC cis rs9549367 0.789 rs3764124 chr13:113897320 C/T cg00898013 chr13:113819073 PROZ -0.43 -7.4 -0.37 1.03e-12 Platelet distribution width; LIHC cis rs8177179 0.967 rs6439434 chr3:133450371 T/G cg18769074 chr3:133464867 TF 0.27 6.09 0.31 3.02e-9 Iron status biomarkers (transferrin levels); LIHC cis rs765787 0.530 rs28897155 chr15:45533974 T/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs10489202 1.000 rs34058770 chr1:168057399 C/A cg24449463 chr1:168025552 DCAF6 -0.5 -6.35 -0.32 6.85e-10 Schizophrenia; LIHC cis rs6785206 1.000 rs2712370 chr3:128425204 C/G cg16766828 chr3:128327626 NA -0.59 -6.59 -0.34 1.63e-10 Lymphocyte percentage of white cells; LIHC cis rs4304924 0.500 rs9601109 chr13:79220114 A/G cg01819759 chr13:79234251 RNF219 0.49 6.36 0.33 6.37e-10 Large artery stroke; LIHC cis rs875971 0.862 rs778720 chr7:65846275 A/C cg11764359 chr7:65958608 NA -0.84 -14.71 -0.62 2.69e-38 Aortic root size; LIHC cis rs2412459 0.831 rs6492924 chr15:40272391 G/A cg16127683 chr15:40268777 EIF2AK4 -0.6 -8.08 -0.4 1.13e-14 Response to haloperidol in psychosis; LIHC cis rs1997103 1.000 rs2177803 chr7:55410773 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs947211 1.000 rs1775151 chr1:205745684 C/T cg14893161 chr1:205819251 PM20D1 0.32 5.79 0.3 1.57e-8 Parkinson's disease; LIHC cis rs3780378 0.875 rs7032785 chr9:5042046 C/T cg02405213 chr9:5042618 JAK2 -0.56 -9.87 -0.47 2.18e-20 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg10755058 chr3:40428713 ENTPD3 0.41 7.13 0.36 6.01e-12 Renal cell carcinoma; LIHC cis rs546131 0.928 rs516228 chr11:34838823 C/T cg11058730 chr11:34937778 PDHX;APIP 0.62 9.34 0.45 1.31e-18 Lung disease severity in cystic fibrosis; LIHC cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg15534755 chr11:117069859 TAGLN 0.4 6.75 0.34 6.42e-11 Blood protein levels; LIHC cis rs7762018 1.000 rs6942332 chr6:170131934 A/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.53 6.41 0.33 4.92e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6964587 1.000 rs9690778 chr7:91735299 A/G cg17063962 chr7:91808500 NA 1.02 19.59 0.73 8.04e-58 Breast cancer; LIHC cis rs2073300 0.609 rs6137915 chr20:23358509 A/G cg12062639 chr20:23401060 NAPB -1.03 -13.51 -0.59 1.28e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2228479 0.618 rs17233623 chr16:89811209 C/T cg14709524 chr16:89940631 TCF25 0.47 5.72 0.3 2.28e-8 Skin colour saturation; LIHC cis rs797680 0.820 rs10874773 chr1:93798496 T/G cg15093775 chr1:93646470 TMED5;CCDC18 -0.33 -5.75 -0.3 1.94e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs17401966 0.931 rs17034821 chr1:10414645 A/G cg15208524 chr1:10270712 KIF1B 0.41 6.04 0.31 4.04e-9 Hepatocellular carcinoma; LIHC cis rs7487075 0.619 rs9971879 chr12:46806773 T/C cg23829395 chr12:46796953 NA 0.35 6.26 0.32 1.16e-9 Itch intensity from mosquito bite; LIHC cis rs208520 1.000 rs12216109 chr6:66987488 C/G cg07460842 chr6:66804631 NA 0.67 7.29 0.37 2.24e-12 Exhaled nitric oxide output; LIHC cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg00106254 chr7:1943704 MAD1L1 -0.43 -6.87 -0.35 3.07e-11 Bipolar disorder and schizophrenia; LIHC cis rs10916814 1.000 rs12145351 chr1:20901181 C/A cg24502330 chr1:20914028 CDA -0.28 -5.87 -0.3 1.05e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs6073597 0.967 rs6031972 chr20:43704943 T/C cg14213297 chr9:130870109 SLC25A25 -0.35 -6.05 -0.31 3.73e-9 Positive affect; LIHC cis rs7582180 0.652 rs11687865 chr2:100947000 T/A cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.97e-16 Intelligence (multi-trait analysis); LIHC cis rs8180040 1.000 rs807810 chr3:47403892 G/A cg27129171 chr3:47204927 SETD2 -0.65 -11.18 -0.52 6.02e-25 Colorectal cancer; LIHC cis rs6430585 0.583 rs59213715 chr2:136646582 A/C cg07169764 chr2:136633963 MCM6 1.35 23.15 0.78 5.47e-72 Corneal structure; LIHC cis rs17685 0.633 rs3801471 chr7:75696188 T/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.53 -0.38 4.7e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs61677309 1.000 rs55806415 chr11:118162862 G/A cg06090739 chr11:118230722 UBE4A 0.34 6.38 0.33 5.86e-10 Lung cancer in ever smokers; LIHC cis rs1211375 0.606 rs1203977 chr16:256278 A/C cg00126636 chr16:237282 NA 0.37 6.39 0.33 5.35e-10 Hematology traits;Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.68 9.84 0.47 2.78e-20 Lymphocyte counts; LIHC cis rs1395 0.744 rs3739092 chr2:27462076 C/T cg23587288 chr2:27483067 SLC30A3 -0.31 -5.8 -0.3 1.51e-8 Blood metabolite levels; LIHC cis rs9443189 0.570 rs775072 chr6:76377998 G/A cg01950844 chr6:76311363 SENP6 -0.86 -10.58 -0.5 7.87e-23 Prostate cancer; LIHC cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg12463550 chr7:65579703 CRCP -0.67 -7.14 -0.36 5.64e-12 Diabetic kidney disease; LIHC cis rs6088590 0.687 rs6088582 chr20:33286798 G/A cg24642439 chr20:33292090 TP53INP2 0.57 8.06 0.4 1.28e-14 Coronary artery disease; LIHC cis rs10883723 0.810 rs6584507 chr10:104254623 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs26868 0.766 rs26867 chr16:2249410 T/C cg02248941 chr16:2239361 CASKIN1 0.35 6.74 0.34 6.95e-11 Height; LIHC cis rs35306767 0.953 rs12762973 chr10:960761 C/G cg20503657 chr10:835505 NA 0.91 10.27 0.49 9.28e-22 Eosinophil percentage of granulocytes; LIHC cis rs9467773 1.000 rs9467791 chr6:26562486 A/G cg11502198 chr6:26597334 ABT1 -0.42 -6.13 -0.31 2.41e-9 Intelligence (multi-trait analysis); LIHC cis rs9309711 0.736 rs9678647 chr2:3497036 A/G cg10845886 chr2:3471009 TTC15 0.45 7.93 0.39 3.07e-14 Neurofibrillary tangles; LIHC cis rs875971 0.666 rs13242072 chr7:65765988 A/G cg18876405 chr7:65276391 NA -0.45 -7.5 -0.38 5.38e-13 Aortic root size; LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg25811766 chr13:21894605 NA 0.8 14.21 0.61 2.52e-36 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6748734 0.779 rs4401206 chr2:241796905 A/G cg09990169 chr2:241835740 C2orf54 -0.64 -10.18 -0.48 1.88e-21 Urinary metabolites; LIHC cis rs611744 0.870 rs638905 chr8:109203406 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs2727020 0.688 rs11040338 chr11:49360601 A/G cg18944383 chr4:111397179 ENPEP -0.25 -6.04 -0.31 4.02e-9 Coronary artery disease; LIHC cis rs3806843 0.966 rs2563263 chr5:140137644 A/G cg19875535 chr5:140030758 IK 0.36 6.07 0.31 3.37e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2404602 0.679 rs12908421 chr15:76881794 T/G cg03037974 chr15:76606532 NA 0.76 14.87 0.63 6.3e-39 Blood metabolite levels; LIHC cis rs6815814 0.861 rs28393318 chr4:38784267 A/G cg06935464 chr4:38784597 TLR10 0.54 9.46 0.46 5.32e-19 Breast cancer; LIHC cis rs7618501 0.571 rs2240329 chr3:50107512 G/A cg21467203 chr3:49911342 NA 0.43 7.65 0.38 2.09e-13 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.933 rs11211203 chr1:46315592 A/G cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2624839 0.679 rs2624835 chr3:50209049 G/A cg21467203 chr3:49911342 NA -0.45 -5.96 -0.31 6.37e-9 Intelligence (multi-trait analysis); LIHC cis rs1728785 0.901 rs3087783 chr16:68599668 C/T cg02972257 chr16:68554789 NA -0.55 -6.26 -0.32 1.15e-9 Ulcerative colitis; LIHC cis rs3853824 0.965 rs1052227 chr17:54906137 C/T cg13675837 chr17:54910204 DGKE -0.41 -5.9 -0.3 8.98e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2274273 0.714 rs7154889 chr14:55806885 G/A cg04306507 chr14:55594613 LGALS3 0.32 5.96 0.31 6.19e-9 Protein biomarker; LIHC cis rs7249142 0.549 rs10854012 chr19:19295719 C/T cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.43 -7.31 -0.37 1.95e-12 IgG glycosylation; LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.48 -6.79 -0.34 5.04e-11 Lymphocyte counts; LIHC cis rs288342 0.797 rs288310 chr2:183650229 G/A cg02625481 chr2:183667124 NA -0.29 -6.02 -0.31 4.55e-9 Recurrent major depressive disorder; LIHC cis rs4665809 0.590 rs7606351 chr2:26292545 A/C cg27170947 chr2:26402098 FAM59B -0.69 -8.57 -0.42 3.65e-16 Gut microbiome composition (summer); LIHC cis rs769267 0.965 rs4808938 chr19:19401218 G/A cg03709012 chr19:19516395 GATAD2A 0.94 15.76 0.65 1.93e-42 Tonsillectomy; LIHC cis rs57502260 0.915 rs75202638 chr11:68210421 C/T cg16797656 chr11:68205561 LRP5 0.62 8.35 0.41 1.75e-15 Total body bone mineral density (age 45-60); LIHC cis rs9790314 1.000 rs9846756 chr3:160983809 A/C cg04691961 chr3:161091175 C3orf57 -0.4 -6.22 -0.32 1.43e-9 Morning vs. evening chronotype; LIHC cis rs4332037 1.000 rs62442899 chr7:1948454 C/T cg23422044 chr7:1970798 MAD1L1 -0.64 -7.3 -0.37 2.03e-12 Bipolar disorder; LIHC cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg06238570 chr21:40685208 BRWD1 0.61 7.29 0.37 2.11e-12 Cognitive function; LIHC cis rs763121 0.853 rs138705 chr22:39133803 C/T cg06022373 chr22:39101656 GTPBP1 0.71 13.46 0.59 1.93e-33 Menopause (age at onset); LIHC cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg13395646 chr4:1353034 KIAA1530 -0.59 -8.72 -0.43 1.24e-16 Obesity-related traits; LIHC cis rs62380364 0.557 rs663046 chr5:88036486 C/T cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis); LIHC cis rs208515 0.525 rs10455593 chr6:66691341 C/T cg07460842 chr6:66804631 NA 0.79 8.97 0.44 1.94e-17 Exhaled nitric oxide levels; LIHC cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg13607699 chr17:42295918 UBTF 0.49 8.0 0.4 1.96e-14 Total body bone mineral density; LIHC cis rs3820068 0.705 rs16851727 chr1:15857918 C/T cg17385448 chr1:15911702 AGMAT 0.36 5.97 0.31 5.91e-9 Systolic blood pressure; LIHC cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.49e-11 Diabetic kidney disease; LIHC cis rs10861342 1.000 rs11112368 chr12:105494218 T/C cg23923672 chr12:105501055 KIAA1033 0.7 8.51 0.42 5.36e-16 IgG glycosylation; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg07021052 chr2:20871279 NA 0.37 7.09 0.36 7.67e-12 Abdominal aortic aneurysm; LIHC cis rs13108904 0.645 rs56115381 chr4:1324994 G/C cg00684032 chr4:1343700 KIAA1530 0.6 8.59 0.42 3.17e-16 Obesity-related traits; LIHC cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg05025164 chr4:1340916 KIAA1530 -0.4 -6.08 -0.31 3.14e-9 Obesity-related traits; LIHC trans rs5417 0.662 rs8067500 chr17:7172631 A/G cg15655154 chr3:113604241 GRAMD1C 0.51 8.35 0.41 1.67e-15 Diastolic blood pressure; LIHC cis rs35110281 0.837 rs7279958 chr21:45016016 C/A cg21573476 chr21:45109991 RRP1B -0.52 -9.74 -0.47 6.01e-20 Mean corpuscular volume; LIHC cis rs11971779 0.878 rs4732378 chr7:139120395 C/T cg07862535 chr7:139043722 LUC7L2 0.69 10.76 0.5 1.93e-23 Diisocyanate-induced asthma; LIHC cis rs1555322 0.505 rs639763 chr20:33861904 C/T cg03689076 chr20:33865952 NA 0.55 6.17 0.32 1.92e-9 Attention deficit hyperactivity disorder; LIHC trans rs1814175 0.653 rs10839480 chr11:50034556 C/T cg03929089 chr4:120376271 NA -0.88 -18.26 -0.7 1.79e-52 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21792150 chr3:101567884 NFKBIZ -0.51 -6.4 -0.33 5.2400000000000005e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg06481639 chr22:41940642 POLR3H 0.71 7.16 0.36 4.86e-12 Vitiligo; LIHC cis rs9918079 0.560 rs7685083 chr4:15610771 G/A cg04067612 chr4:15429572 C1QTNF7 0.28 5.88 0.3 1e-8 Obesity-related traits; LIHC cis rs644799 1.000 rs12786522 chr11:95522858 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.91 0.47 1.6e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs116095464 1.000 rs28416084 chr5:217640 G/A cg22857025 chr5:266934 NA -1.63 -16.72 -0.67 2.82e-46 Breast cancer; LIHC cis rs4595586 0.545 rs3858553 chr12:39381291 A/C cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg00149659 chr3:10157352 C3orf10 0.65 6.37 0.33 6.04e-10 Alzheimer's disease; LIHC cis rs2576037 0.526 rs3892820 chr18:44479558 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 10.19 0.48 1.76e-21 Personality dimensions; LIHC cis rs2228479 0.850 rs17233664 chr16:89810628 C/T cg19635926 chr16:89946313 TCF25 0.49 6.24 0.32 1.28e-9 Skin colour saturation; LIHC cis rs8017423 0.647 rs11626821 chr14:90824945 A/G cg04374321 chr14:90722782 PSMC1 -0.48 -7.1 -0.36 7.34e-12 Mortality in heart failure; LIHC cis rs10744422 1.000 rs7139055 chr12:123364198 A/G cg25930673 chr12:123319894 HIP1R 0.91 11.46 0.53 6.1e-26 Schizophrenia; LIHC cis rs875971 0.862 rs1167390 chr7:65575893 G/A cg18876405 chr7:65276391 NA -0.39 -6.85 -0.35 3.53e-11 Aortic root size; LIHC cis rs4253772 0.591 rs6007748 chr22:46657798 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.72 6.52 0.33 2.55e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs875971 0.862 rs6945775 chr7:65968974 G/A cg11764359 chr7:65958608 NA 0.85 15.31 0.64 1.2e-40 Aortic root size; LIHC cis rs17401966 1.000 rs3753037 chr1:10355834 C/T cg19773385 chr1:10388646 KIF1B -0.48 -8.38 -0.41 1.35e-15 Hepatocellular carcinoma; LIHC cis rs116095464 0.558 rs2288459 chr5:231143 T/C cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs6543140 0.890 rs61122764 chr2:102999520 A/G cg09003973 chr2:102972529 NA 0.54 6.06 0.31 3.63e-9 Blood protein levels; LIHC cis rs400736 0.740 rs225118 chr1:8108754 G/A cg25007680 chr1:8021821 PARK7 0.53 8.1 0.4 9.58e-15 Response to antidepressants and depression; LIHC cis rs12479064 0.724 rs2305352 chr2:100015124 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -6.94 -0.35 1.99e-11 Chronic sinus infection; LIHC cis rs3770081 1.000 rs17584578 chr2:86307624 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.85 9.65 0.46 1.2e-19 Facial emotion recognition (sad faces); LIHC trans rs911555 0.723 rs4906320 chr14:103876925 T/C cg17675199 chr6:35436792 RPL10A -0.41 -8.35 -0.41 1.7e-15 Intelligence (multi-trait analysis); LIHC cis rs4474465 0.915 rs12288436 chr11:78161430 T/C cg02023728 chr11:77925099 USP35 0.34 6.11 0.31 2.67e-9 Alzheimer's disease (survival time); LIHC cis rs4803468 1.000 rs2241711 chr19:41911980 T/C cg14132834 chr19:41945861 ATP5SL -0.43 -6.34 -0.32 7.13e-10 Height; LIHC cis rs7412746 0.588 rs10305664 chr1:150839686 A/C cg17724175 chr1:150552817 MCL1 0.47 9.05 0.44 1.11e-17 Melanoma; LIHC cis rs1003719 0.788 rs4817845 chr21:38447132 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg24846343 chr22:24311635 DDTL 0.64 12.12 0.55 2.19e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs912057 0.901 rs744056 chr6:6733540 A/G cg06612196 chr6:6737390 NA 0.44 8.05 0.4 1.36e-14 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs16912285 0.748 rs7104694 chr11:24280281 A/C ch.11.24196551F chr11:24239977 NA 0.77 10.62 0.5 5.73e-23 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs769267 0.930 rs2301784 chr19:19390749 G/A cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.72 0.3 2.38e-8 Vitiligo; LIHC cis rs2070488 0.965 rs2126534 chr3:38445165 T/G cg24069376 chr3:38537580 EXOG 0.43 7.73 0.39 1.24e-13 Electrocardiographic conduction measures; LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.76 -0.34 6.07e-11 Total body bone mineral density; LIHC cis rs9457247 1.000 rs397713 chr6:167386714 G/A cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs11671005 0.611 rs56026876 chr19:59006157 G/C cg25952890 chr19:58913133 NA 0.68 6.95 0.35 1.86e-11 Mean platelet volume; LIHC cis rs7116495 1.000 rs2511079 chr11:71804154 C/T cg26138937 chr11:71823887 C11orf51 -0.78 -7.92 -0.39 3.26e-14 Severe influenza A (H1N1) infection; LIHC cis rs34172651 0.876 rs7186893 chr16:24806420 G/T cg00152838 chr16:24741724 TNRC6A -0.49 -6.56 -0.33 2.01e-10 Intelligence (multi-trait analysis); LIHC cis rs11711311 1.000 rs891574 chr3:113537639 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -6.89 -0.35 2.65e-11 IgG glycosylation; LIHC cis rs765787 0.530 rs55920042 chr15:45541577 G/A cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16574807 chr4:6945745 TBC1D14 -0.4 -6.57 -0.33 1.83e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs910316 0.737 rs175065 chr14:75494983 T/C cg11812906 chr14:75593930 NEK9 -0.75 -13.84 -0.6 6.67e-35 Height; LIHC cis rs932287 0.505 rs2742536 chr11:8909816 G/C cg12365402 chr11:9010492 NRIP3 -0.26 -6.72 -0.34 7.65e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs11711311 0.822 rs9850256 chr3:113408382 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.37 6.93 0.35 2.07e-11 IgG glycosylation; LIHC cis rs10791097 0.694 rs1054869 chr11:130742630 G/A cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs3960554 0.808 rs111764601 chr7:75706141 T/C cg19862616 chr7:65841803 NCRNA00174 0.63 8.71 0.43 1.35e-16 Eotaxin levels; LIHC cis rs7937682 0.632 rs10891297 chr11:111770150 C/T cg09085632 chr11:111637200 PPP2R1B 0.92 12.98 0.57 1.38e-31 Primary sclerosing cholangitis; LIHC cis rs1552244 0.554 rs3732963 chr3:10048885 G/T cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08504806 chr7:2027239 MAD1L1 0.42 6.23 0.32 1.36e-9 Pancreatic cancer; LIHC cis rs2282802 0.685 rs62385161 chr5:139635747 T/C cg26211634 chr5:139558579 C5orf32 0.39 5.97 0.31 6.1e-9 Intelligence (multi-trait analysis); LIHC cis rs908922 0.676 rs1337340 chr1:152508260 T/C cg20991723 chr1:152506922 NA 0.55 9.52 0.46 3.34e-19 Hair morphology; LIHC cis rs7584330 0.736 rs6431541 chr2:238376190 A/T cg14458575 chr2:238380390 NA 0.37 5.73 0.3 2.19e-8 Prostate cancer; LIHC cis rs244293 0.701 rs4793783 chr17:53025480 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.03 -0.31 4.32e-9 Menarche (age at onset); LIHC cis rs3099143 1.000 rs3110381 chr15:77099665 A/T cg21673338 chr15:77095150 SCAPER -0.49 -7.43 -0.37 9.04e-13 Recalcitrant atopic dermatitis; LIHC cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg06481639 chr22:41940642 POLR3H 0.71 7.17 0.36 4.8e-12 Vitiligo; LIHC cis rs12602486 1.000 rs74635090 chr17:42219267 G/A cg13607699 chr17:42295918 UBTF -0.72 -6.27 -0.32 1.12e-9 Glycated hemoglobin levels; LIHC cis rs10911251 0.546 rs1062044 chr1:183112412 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 3.82e-23 Colorectal cancer; LIHC cis rs1707322 0.721 rs7520123 chr1:46235219 C/G cg06784218 chr1:46089804 CCDC17 0.38 7.03 0.36 1.13e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg07061783 chr6:25882402 NA -0.43 -6.03 -0.31 4.14e-9 Blood metabolite levels; LIHC cis rs1865760 1.000 rs3752421 chr6:25918688 G/A cg17691542 chr6:26056736 HIST1H1C 0.42 6.27 0.32 1.1e-9 Height; LIHC cis rs2297441 0.550 rs6011097 chr20:62398825 G/A cg14758556 chr20:62440591 NA -0.45 -7.22 -0.36 3.39e-12 Ulcerative colitis; LIHC cis rs11971779 0.680 rs6963867 chr7:139059964 T/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2576037 0.583 rs8098948 chr18:44512332 C/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.72 11.49 0.53 4.74e-26 Personality dimensions; LIHC cis rs798554 0.704 rs2527684 chr7:2825922 G/T cg19717773 chr7:2847554 GNA12 -0.4 -7.32 -0.37 1.77e-12 Height; LIHC cis rs1707322 0.721 rs6429575 chr1:46134216 G/C cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1005277 0.522 rs200943 chr10:38148730 A/G cg27523141 chr10:43048294 ZNF37B 0.39 6.86 0.35 3.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs9513627 0.920 rs7334943 chr13:100121287 C/G cg25919922 chr13:100150906 NA 0.73 6.56 0.33 1.97e-10 Obesity-related traits; LIHC cis rs875971 0.862 rs4718330 chr7:65715243 G/A cg18876405 chr7:65276391 NA -0.36 -6.49 -0.33 3.04e-10 Aortic root size; LIHC cis rs1577917 0.740 rs6926049 chr6:86266133 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 11.79 0.54 3.62e-27 Response to antipsychotic treatment; LIHC cis rs1568889 1.000 rs12808162 chr11:28067027 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.81 0.35 4.36e-11 Bipolar disorder; LIHC trans rs9951602 0.512 rs9946120 chr18:76654548 A/T cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs332507 0.830 rs1846891 chr3:124399397 A/G cg05980111 chr3:124395277 KALRN 0.45 7.05 0.36 9.91e-12 Plateletcrit; LIHC cis rs11671005 0.569 rs73068335 chr19:59089308 C/G cg25952890 chr19:58913133 NA 0.66 6.75 0.34 6.52e-11 Mean platelet volume; LIHC cis rs11098499 1.000 rs28419773 chr4:120211061 T/C cg09307838 chr4:120376055 NA 0.72 10.66 0.5 4.1000000000000003e-23 Corneal astigmatism; LIHC cis rs7208859 0.573 rs11656121 chr17:29214043 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs61990749 0.544 rs8003979 chr14:78211290 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.16 0.48 2.37e-21 Fibroblast growth factor basic levels; LIHC cis rs72829446 0.530 rs8075009 chr17:7374508 A/T cg02795151 chr17:7402630 POLR2A 0.55 5.8 0.3 1.52e-8 Androgen levels; LIHC cis rs459571 0.916 rs467303 chr9:136904835 C/T cg13789015 chr9:136890014 NCRNA00094 0.46 8.28 0.41 2.75e-15 Platelet distribution width; LIHC cis rs10464366 0.544 rs2280667 chr7:39172228 A/C cg20302533 chr7:39170763 POU6F2 0.38 6.98 0.35 1.52e-11 IgG glycosylation; LIHC cis rs2204008 0.744 rs67889662 chr12:38327042 T/A cg26384229 chr12:38710491 ALG10B 0.87 10.79 0.5 1.46e-23 Bladder cancer; LIHC cis rs929354 0.772 rs6969244 chr7:157004012 A/G cg17757837 chr7:157058334 UBE3C 0.74 12.05 0.55 4.26e-28 Body mass index; LIHC cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.52 -0.56 7.42e-30 Alzheimer's disease; LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.64 -0.42 2.21e-16 Lymphocyte counts; LIHC cis rs7100689 0.622 rs10887798 chr10:82131613 G/A cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.24e-12 Post bronchodilator FEV1; LIHC cis rs7098414 0.511 rs10466236 chr10:82149717 C/T cg00277334 chr10:82204260 NA 0.58 9.58 0.46 2.08e-19 Post bronchodilator FEV1; LIHC cis rs7584330 0.554 rs10178682 chr2:238433818 T/G cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.39e-9 Prostate cancer; LIHC cis rs8180040 0.726 rs10461018 chr3:46995242 C/T cg27129171 chr3:47204927 SETD2 -0.62 -10.74 -0.5 2.19e-23 Colorectal cancer; LIHC cis rs6920965 0.507 rs4285341 chr6:126205589 T/G cg05901451 chr6:126070800 HEY2 -0.36 -6.17 -0.32 1.9e-9 High light scatter reticulocyte count; LIHC cis rs7552404 1.000 rs12126607 chr1:76217097 G/A cg10523679 chr1:76189770 ACADM 0.63 8.78 0.43 7.88e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg05665937 chr4:1216051 CTBP1 -0.45 -5.98 -0.31 5.57e-9 Obesity-related traits; LIHC cis rs7945705 0.520 rs1984791 chr11:9035027 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.38 5.87 0.3 1.05e-8 Hemoglobin concentration; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg11494091 chr17:61959527 GH2 0.45 8.12 0.4 8.63e-15 Prudent dietary pattern; LIHC trans rs4753788 0.511 rs12224337 chr11:107140077 G/A cg09581611 chr16:67978158 SLC12A4;LCAT 0.3 6.06 0.31 3.63e-9 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26309655 chr1:150459725 TARS2 0.44 6.18 0.32 1.83e-9 Lung function (FEV1/FVC); LIHC cis rs916888 0.821 rs415430 chr17:44859144 C/T cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9303280 0.806 rs10852935 chr17:38031674 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.15 0.36 5.31e-12 Self-reported allergy; LIHC cis rs780096 0.565 rs10169261 chr2:27727314 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.4 -6.02 -0.31 4.54e-9 Total body bone mineral density; LIHC cis rs2832077 0.527 rs2705690 chr21:30239245 T/A cg03476357 chr21:30257390 N6AMT1 0.55 8.01 0.4 1.84e-14 Cognitive test performance; LIHC cis rs778371 0.723 rs10210953 chr2:233698830 G/A cg08000102 chr2:233561755 GIGYF2 -0.87 -14.54 -0.62 1.25e-37 Schizophrenia; LIHC cis rs6502050 0.731 rs35156322 chr17:80096323 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.59e-9 Life satisfaction; LIHC cis rs7772486 0.875 rs9403765 chr6:146368041 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -5.85 -0.3 1.17e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2404602 0.532 rs284892 chr15:76721037 A/G cg03037974 chr15:76606532 NA 0.67 12.5 0.56 8.94e-30 Blood metabolite levels; LIHC cis rs611744 0.967 rs678387 chr8:109242730 G/C cg21045802 chr8:109455806 TTC35 0.5 8.65 0.42 2.05e-16 Dupuytren's disease; LIHC cis rs58235267 0.543 rs2539990 chr2:63170185 C/T cg17519650 chr2:63277830 OTX1 0.58 9.57 0.46 2.23e-19 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs2806561 0.734 rs1952527 chr1:23400969 T/C cg12483005 chr1:23474871 LUZP1 0.45 6.98 0.35 1.5e-11 Height; LIHC cis rs4474465 0.850 rs7122676 chr11:78268525 A/G cg27205649 chr11:78285834 NARS2 0.47 7.23 0.36 3.23e-12 Alzheimer's disease (survival time); LIHC trans rs62103177 0.810 rs62103175 chr18:77622467 C/T cg05926928 chr17:57297772 GDPD1 1.1 11.28 0.52 2.73e-25 Opioid sensitivity; LIHC cis rs9814567 1.000 rs6763093 chr3:134254995 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs61931739 0.534 rs10844828 chr12:34303109 C/T cg26384229 chr12:38710491 ALG10B 0.47 6.34 0.32 7.42e-10 Morning vs. evening chronotype; LIHC cis rs904251 0.523 rs2797796 chr6:37480886 T/C cg01843034 chr6:37503916 NA -0.48 -8.26 -0.41 3.26e-15 Cognitive performance; LIHC cis rs67460515 0.500 rs1562464 chr3:160681614 G/A cg03342759 chr3:160939853 NMD3 -0.54 -7.5 -0.38 5.47e-13 Parkinson's disease; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg11494091 chr17:61959527 GH2 0.45 8.31 0.41 2.33e-15 Prudent dietary pattern; LIHC cis rs11239930 1.000 rs11239930 chr1:146560564 C/T cg25205988 chr1:146714368 CHD1L -0.37 -5.83 -0.3 1.32e-8 AIDS progression; LIHC cis rs16912285 0.748 rs7952223 chr11:24256443 G/C ch.11.24196551F chr11:24239977 NA 0.7 8.65 0.42 2.06e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg08424446 chr12:133381374 GOLGA3 0.43 6.43 0.33 4.4e-10 Electroencephalogram traits; LIHC cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg05368731 chr17:41323189 NBR1 0.72 12.47 0.56 1.08e-29 Menopause (age at onset); LIHC cis rs1348850 0.567 rs4144276 chr2:178523420 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.83 0.39 6.06e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6500602 0.702 rs3761680 chr16:4524060 C/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.46 6.55 0.33 2.17e-10 Schizophrenia; LIHC cis rs34779708 0.931 rs67261877 chr10:35386340 T/A cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9649213 0.593 rs62478233 chr7:98023092 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.81 -0.3 1.41e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs10883723 0.773 rs7917402 chr10:104246690 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.12 0.58 4.01e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2302190 0.882 rs2270098 chr17:56572081 C/T cg12560992 chr17:57184187 TRIM37 0.73 9.14 0.44 5.78e-18 Vitamin D levels; LIHC cis rs11608355 0.545 rs2302703 chr12:109898832 G/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs9902453 0.817 rs67206808 chr17:28190096 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 12.4 0.56 2.13e-29 Coffee consumption (cups per day); LIHC cis rs7412746 0.658 rs1027699 chr1:150811712 T/C cg18016565 chr1:150552671 MCL1 0.54 10.31 0.49 6.73e-22 Melanoma; LIHC cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.77 -0.5 1.68e-23 Platelet count; LIHC cis rs6960043 0.818 rs10244051 chr7:15063833 T/G cg19272540 chr7:15055459 NA -0.23 -6.3 -0.32 9.34e-10 Type 2 diabetes; LIHC cis rs2531992 0.686 rs933392 chr16:4032716 T/G cg05927578 chr16:4029543 ADCY9 0.52 7.12 0.36 6.38e-12 Waist circumference; LIHC trans rs801193 0.660 rs974239 chr7:66213491 G/A cg10756647 chr7:56101905 PSPH 0.47 6.95 0.35 1.88e-11 Aortic root size; LIHC cis rs9733 0.818 rs6694531 chr1:150683512 C/A cg17724175 chr1:150552817 MCL1 -0.38 -7.85 -0.39 5.49e-14 Tonsillectomy; LIHC trans rs1814175 0.645 rs4625470 chr11:49983769 T/C cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs5769765 0.908 rs4824109 chr22:50271460 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs6502050 0.805 rs6502061 chr17:80086158 C/T cg11859384 chr17:80120422 CCDC57 0.43 5.95 0.31 6.76e-9 Life satisfaction; LIHC cis rs9814567 0.727 rs4543053 chr3:134351724 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.53 -8.58 -0.42 3.41e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9457247 0.902 rs34560498 chr6:167395862 A/G cg23791538 chr6:167370224 RNASET2 -0.69 -11.73 -0.54 5.95e-27 Crohn's disease; LIHC cis rs11822910 0.906 rs11822095 chr11:57194155 G/A cg00522883 chr11:57194120 SLC43A3 0.7 8.35 0.41 1.67e-15 Platelet distribution width; LIHC cis rs3008870 1.000 rs2985817 chr1:67398607 G/C cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.21 -0.32 1.5e-9 Total body bone mineral density; LIHC cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg18404041 chr3:52824283 ITIH1 -0.55 -8.97 -0.44 2.04e-17 Bipolar disorder; LIHC cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg27170947 chr2:26402098 FAM59B -0.72 -8.67 -0.42 1.7e-16 Gut microbiome composition (summer); LIHC cis rs7847628 0.587 rs1060817 chr9:123583192 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.77 13.24 0.58 1.41e-32 Birth weight; LIHC cis rs6684514 1.000 rs2270291 chr1:156244992 G/C cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg20607798 chr8:58055168 NA 0.49 6.13 0.31 2.37e-9 Developmental language disorder (linguistic errors); LIHC cis rs1494950 1.000 rs10212717 chr4:14990560 T/C cg12377275 chr4:15005593 CPEB2 -0.79 -6.68 -0.34 9.49e-11 Political ideology; LIHC cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg27170947 chr2:26402098 FAM59B -0.67 -8.3 -0.41 2.49e-15 Gut microbiome composition (summer); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13898564 chr9:78504994 PCSK5 -0.48 -6.16 -0.32 2.09e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2257205 0.588 rs7214266 chr17:56851920 C/T cg12560992 chr17:57184187 TRIM37 0.68 7.44 0.37 8.24e-13 Pancreatic cancer; LIHC cis rs12530845 0.623 rs73721677 chr7:135354238 C/A cg23117316 chr7:135346802 PL-5283 -0.41 -5.94 -0.31 7.17e-9 Red blood cell traits; LIHC cis rs9896052 0.580 rs7406977 chr17:73460417 T/G cg25649188 chr17:73499917 CASKIN2 0.44 6.85 0.35 3.37e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs1448094 0.511 rs17345975 chr12:86202318 T/A cg02569458 chr12:86230093 RASSF9 0.46 6.0 0.31 5.04e-9 Major depressive disorder; LIHC cis rs2370759 1.000 rs2769241 chr10:32556229 T/C cg01819863 chr10:32635814 EPC1 -1.12 -16.58 -0.67 9.59e-46 Sexual dysfunction (female); LIHC cis rs7959452 0.719 rs57954211 chr12:69748397 C/A cg14784868 chr12:69753453 YEATS4 0.97 20.41 0.74 3.92e-61 Blood protein levels; LIHC cis rs2239547 0.603 rs59989280 chr3:53098875 T/C cg11645453 chr3:52864694 ITIH4 0.28 7.01 0.35 1.28e-11 Schizophrenia; LIHC cis rs3790844 0.678 rs3790854 chr1:200000125 C/T cg07208853 chr1:200005219 NR5A2 -0.38 -8.56 -0.42 3.75e-16 Pancreatic cancer; LIHC cis rs1030268 0.651 rs13222377 chr7:133466346 C/T cg03336402 chr7:133662267 EXOC4 -0.51 -6.2 -0.32 1.6e-9 Intelligence (multi-trait analysis); LIHC cis rs2997447 0.706 rs12062488 chr1:26466253 G/A cg19633962 chr1:26362018 EXTL1 -0.65 -5.86 -0.3 1.06e-8 QRS complex (12-leadsum); LIHC cis rs4908768 0.911 rs953535 chr1:8776719 A/C cg20416874 chr1:8611966 RERE 0.52 7.84 0.39 5.6e-14 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs965469 1.000 rs6133036 chr20:3349682 A/G cg25506879 chr20:3388711 C20orf194 -0.54 -6.52 -0.33 2.58e-10 IFN-related cytopenia; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg05481257 chr2:20870211 GDF7 0.4 8.14 0.4 7.53e-15 Abdominal aortic aneurysm; LIHC cis rs9303280 0.836 rs11557467 chr17:38028634 G/T cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.92 0.3 7.8e-9 Self-reported allergy; LIHC trans rs7615952 0.551 rs6438945 chr3:125634473 G/A cg07211511 chr3:129823064 LOC729375 -0.86 -10.47 -0.49 2.03e-22 Blood pressure (smoking interaction); LIHC cis rs1322512 1.000 rs2758812 chr6:152965908 C/T cg03415253 chr6:152958462 SYNE1 -0.33 -6.22 -0.32 1.47e-9 Tonometry; LIHC cis rs694739 0.726 rs516124 chr11:64128423 G/T cg02228329 chr11:64053129 BAD;GPR137 0.59 8.14 0.4 7.21e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs11676855 0.927 rs4341884 chr2:235918504 G/T cg02447239 chr2:235936137 SH3BP4 -0.36 -6.28 -0.32 1.01e-9 Dialysis-related mortality; LIHC cis rs798554 0.797 rs2107964 chr7:2863574 G/A cg13628971 chr7:2884303 GNA12 0.58 8.03 0.4 1.62e-14 Height; LIHC cis rs801193 0.527 rs2707837 chr7:66181073 G/C cg18876405 chr7:65276391 NA 0.33 5.97 0.31 5.9e-9 Aortic root size; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg08219700 chr8:58056026 NA 0.52 7.15 0.36 5.24e-12 Developmental language disorder (linguistic errors); LIHC cis rs12926788 0.546 rs200531 chr16:24756172 G/A cg00339695 chr16:24857497 SLC5A11 -0.72 -10.75 -0.5 2.11e-23 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs950169 0.724 rs11632668 chr15:84948687 T/C cg17507749 chr15:85114479 UBE2QP1 0.74 8.69 0.43 1.55e-16 Schizophrenia; LIHC cis rs10792665 0.512 rs7106981 chr11:82600876 C/T cg24227371 chr11:82718527 RAB30 -0.28 -6.56 -0.33 1.97e-10 Obesity-related traits; LIHC cis rs757081 0.667 rs615424 chr11:17210481 G/A cg15432903 chr11:17409602 KCNJ11 -0.44 -6.08 -0.31 3.26e-9 Systolic blood pressure; LIHC cis rs765787 0.530 rs3759893 chr15:45542950 G/T cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC cis rs9902453 0.845 rs7209622 chr17:28256807 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 14.24 0.61 1.92e-36 Coffee consumption (cups per day); LIHC cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg25072359 chr17:41440525 NA 0.37 5.86 0.3 1.07e-8 Menopause (age at onset); LIHC cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg07414643 chr4:187882934 NA 0.24 6.09 0.31 3.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9918079 0.560 rs7662032 chr4:15635414 C/G cg21329975 chr4:15471214 CC2D2A -0.41 -6.19 -0.32 1.73e-9 Obesity-related traits; LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg26354017 chr1:205819088 PM20D1 0.85 12.58 0.56 4.47e-30 Menarche (age at onset); LIHC cis rs7582720 1.000 rs72932574 chr2:203866336 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.1 0.31 2.88e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs67981189 0.593 rs2526847 chr14:71422274 G/A cg15816911 chr14:71606274 NA -0.4 -6.48 -0.33 3.12e-10 Schizophrenia; LIHC cis rs5769765 0.955 rs9616204 chr22:50303530 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.85 -10.48 -0.49 1.84e-22 Schizophrenia; LIHC cis rs3617 0.598 rs56214994 chr3:52878600 G/C cg11645453 chr3:52864694 ITIH4 -0.23 -6.14 -0.31 2.34e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs35883536 0.513 rs6577180 chr1:101016939 G/A cg14515779 chr1:101123966 NA -0.46 -6.54 -0.33 2.19e-10 Monocyte count; LIHC cis rs1801251 1.000 rs283476 chr2:233650168 A/G cg08000102 chr2:233561755 GIGYF2 0.75 11.43 0.53 7.94e-26 Coronary artery disease; LIHC cis rs7772486 0.790 rs3923579 chr6:146230232 C/G cg13319975 chr6:146136371 FBXO30 0.38 6.15 0.32 2.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs727563 0.520 rs132773 chr22:42031768 T/A cg03806693 chr22:41940476 POLR3H 0.98 10.67 0.5 4.01e-23 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9640161 0.659 rs59572505 chr7:150014986 C/T cg17279839 chr7:150038598 RARRES2 0.48 10.02 0.48 6.83e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs8060686 0.641 rs76501820 chr16:68114582 G/A cg05110241 chr16:68378359 PRMT7 -0.56 -6.12 -0.31 2.62e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs10463316 0.894 rs4099170 chr5:150766583 G/A cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.07e-10 Metabolite levels (Pyroglutamine); LIHC cis rs6459788 0.527 rs6980250 chr7:157228710 C/T cg06271696 chr7:157225062 NA -0.54 -9.98 -0.47 9.3e-21 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs2439831 0.681 rs7168940 chr15:43633334 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 11.09 0.51 1.3e-24 Lung cancer in ever smokers; LIHC cis rs9300255 0.602 rs1716168 chr12:123651966 C/G cg00376283 chr12:123451042 ABCB9 -0.66 -7.38 -0.37 1.23e-12 Neutrophil percentage of white cells; LIHC cis rs17286411 0.750 rs4788561 chr16:71878255 G/A cg06353428 chr16:71660113 MARVELD3 0.55 6.92 0.35 2.18e-11 Blood protein levels; LIHC cis rs875971 0.789 rs10260426 chr7:65736042 G/T cg18252515 chr7:66147081 NA 0.47 6.89 0.35 2.67e-11 Aortic root size; LIHC cis rs2760061 0.545 rs1745423 chr1:228224153 G/T cg02753203 chr1:228287806 NA -0.58 -9.38 -0.45 9.16e-19 Diastolic blood pressure; LIHC cis rs1144333 0.850 rs1251273 chr1:76288617 A/G cg10523679 chr1:76189770 ACADM -0.46 -6.66 -0.34 1.13e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs919433 0.927 rs6759834 chr2:198204860 C/T cg03934865 chr2:198174659 NA -0.57 -8.99 -0.44 1.71e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6582630 0.555 rs10880544 chr12:38473464 G/C cg13010199 chr12:38710504 ALG10B 0.43 5.75 0.3 1.99e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs881375 0.967 rs3761849 chr9:123690957 C/T cg14580859 chr9:123691850 NA 0.38 6.66 0.34 1.12e-10 Rheumatoid arthritis; LIHC cis rs4970988 0.556 rs6681426 chr1:150586971 G/A cg17724175 chr1:150552817 MCL1 -0.56 -11.51 -0.53 3.86e-26 Urate levels; LIHC cis rs72653721 0.838 rs911196 chr6:10990751 T/G cg13562911 chr6:11044106 ELOVL2 0.52 7.41 0.37 1.03e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC trans rs4843747 0.671 rs74729706 chr16:88104159 C/T cg09572067 chr16:29127029 RRN3P2 0.51 8.16 0.4 6.36e-15 Menopause (age at onset); LIHC cis rs11229030 0.893 rs2584859 chr11:57207447 A/G cg00522883 chr11:57194120 SLC43A3 0.43 6.13 0.31 2.44e-9 Crohn's disease; LIHC cis rs7937682 0.889 rs578022 chr11:111490552 G/T cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs9660992 0.710 rs7367930 chr1:205235512 A/G cg21545522 chr1:205238299 TMCC2 0.43 8.09 0.4 1.05e-14 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg11644478 chr21:40555479 PSMG1 0.77 9.67 0.46 9.97e-20 Cognitive function; LIHC cis rs8017423 0.967 rs7147809 chr14:90715025 A/G cg14092571 chr14:90743983 NA -0.38 -6.04 -0.31 4.12e-9 Mortality in heart failure; LIHC trans rs877282 0.853 rs7069720 chr10:754487 A/G cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs2286503 0.839 rs10276099 chr7:22862950 G/A cg11367502 chr7:22862612 TOMM7 0.45 7.51 0.38 5.08e-13 Fibrinogen; LIHC cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg03264133 chr6:25882463 NA -0.53 -6.5 -0.33 2.9e-10 Intelligence (multi-trait analysis); LIHC cis rs637571 0.565 rs570387 chr11:65637076 T/C cg26695010 chr11:65641043 EFEMP2 0.55 7.55 0.38 4.06e-13 Eosinophil percentage of white cells; LIHC cis rs7945705 0.902 rs10743095 chr11:8936984 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.39 6.6 0.34 1.59e-10 Hemoglobin concentration; LIHC cis rs17125944 0.615 rs6572867 chr14:53319283 C/T cg00686598 chr14:53173677 PSMC6 -0.84 -9.84 -0.47 2.68e-20 Alzheimer's disease (late onset); LIHC cis rs7208859 0.623 rs216433 chr17:28921860 T/C cg13385521 chr17:29058706 SUZ12P 0.58 5.8 0.3 1.54e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1552244 0.572 rs67227131 chr3:10172744 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 8.72 0.43 1.19e-16 Alzheimer's disease; LIHC cis rs7089973 0.604 rs17095662 chr10:116596071 A/C cg23260525 chr10:116636907 FAM160B1 0.38 7.54 0.38 4.2e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs826838 0.967 rs11183577 chr12:38781887 A/G cg26384229 chr12:38710491 ALG10B 1.05 14.05 0.6 1.05e-35 Heart rate; LIHC cis rs2075371 0.796 rs1646645 chr7:134012232 G/T cg20476274 chr7:133979776 SLC35B4 -0.61 -10.3 -0.49 7.37e-22 Mean platelet volume; LIHC trans rs116095464 0.850 rs10055295 chr5:243749 G/A cg00938859 chr5:1591904 SDHAP3 0.57 7.07 0.36 8.57e-12 Breast cancer; LIHC cis rs7208859 0.623 rs8067035 chr17:29102188 T/C cg13385521 chr17:29058706 SUZ12P 0.81 8.06 0.4 1.27e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs62244186 0.659 rs4431151 chr3:44510906 G/C cg25364880 chr3:44379878 C3orf23 0.59 8.22 0.41 4.39e-15 Depressive symptoms; LIHC cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 8.79 0.43 7.16e-17 Platelet count; LIHC cis rs6960043 0.875 rs10249299 chr7:15054391 C/T cg19272540 chr7:15055459 NA 0.26 7.15 0.36 5.38e-12 Type 2 diabetes; LIHC cis rs796364 0.951 rs769952 chr2:200734368 C/T cg23649088 chr2:200775458 C2orf69 0.49 5.85 0.3 1.18e-8 Schizophrenia; LIHC cis rs7582720 0.943 rs72926800 chr2:203829225 A/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9733 0.650 rs6698495 chr1:150564476 T/C cg17724175 chr1:150552817 MCL1 -0.37 -7.47 -0.37 6.62e-13 Tonsillectomy; LIHC cis rs6977660 1.000 rs2892940 chr7:19794750 G/A cg07541023 chr7:19748670 TWISTNB 0.42 6.34 0.32 7.3e-10 Thyroid stimulating hormone; LIHC cis rs4808199 0.947 rs1465695 chr19:19588546 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.41 5.76 0.3 1.89e-8 Nonalcoholic fatty liver disease; LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg26354017 chr1:205819088 PM20D1 0.74 11.01 0.51 2.56e-24 Menarche (age at onset); LIHC cis rs611744 0.967 rs671139 chr8:109191260 C/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs12477438 0.501 rs6753063 chr2:99801469 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.16 0.77 4.33e-68 Chronic sinus infection; LIHC cis rs933688 0.526 rs9293565 chr5:90609736 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.42 6.49 0.33 3.07e-10 Smoking behavior; LIHC cis rs66887589 0.870 rs10518336 chr4:120522934 G/A cg09307838 chr4:120376055 NA 0.53 8.17 0.4 5.97e-15 Diastolic blood pressure; LIHC cis rs1577917 0.876 rs66986937 chr6:86532191 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.48 -7.6 -0.38 2.79e-13 Response to antipsychotic treatment; LIHC cis rs9457247 0.565 rs2038580 chr6:167456490 A/T cg23791538 chr6:167370224 RNASET2 -0.52 -7.72 -0.39 1.31e-13 Crohn's disease; LIHC cis rs12497850 0.931 rs9867373 chr3:48960938 A/T cg07636037 chr3:49044803 WDR6 0.93 16.95 0.68 3.21e-47 Parkinson's disease; LIHC cis rs2842992 0.662 rs2273826 chr6:160211421 A/G cg11366901 chr6:160182831 ACAT2 0.86 14.38 0.61 5.22e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs17688076 0.511 rs2418738 chr16:68122604 G/C cg05110241 chr16:68378359 PRMT7 -0.58 -6.84 -0.35 3.64e-11 C-reactive protein levels or HDL-cholesterol levels (pleiotropy); LIHC cis rs921968 0.643 rs613539 chr2:219455967 G/T cg18887096 chr2:219472410 PLCD4 0.37 6.39 0.33 5.47e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3736485 0.966 rs11634039 chr15:51895575 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.29 -0.32 9.52e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs9500256 0.967 rs4928431 chr6:58306258 A/G cg03371099 chr6:57305889 PRIM2 0.36 6.47 0.33 3.41e-10 Eosinophilic esophagitis (pediatric); LIHC cis rs636291 0.517 rs12565133 chr1:10544988 A/C cg17425144 chr1:10567563 PEX14 -0.52 -10.32 -0.49 6.69e-22 Prostate cancer; LIHC trans rs62103177 0.564 rs3930043 chr18:77723832 G/A cg05926928 chr17:57297772 GDPD1 0.64 6.74 0.34 6.76e-11 Opioid sensitivity; LIHC cis rs9467773 1.000 rs10214634 chr6:26564582 T/A cg11502198 chr6:26597334 ABT1 0.45 6.51 0.33 2.66e-10 Intelligence (multi-trait analysis); LIHC cis rs11628318 0.802 rs6575926 chr14:103050183 G/A cg01864069 chr14:103024347 NA -0.57 -9.1 -0.44 7.59e-18 Platelet count; LIHC cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 12.63 0.56 2.73e-30 Alzheimer's disease; LIHC cis rs12477438 0.520 rs13018891 chr2:99755099 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.8 0.65 1.35e-42 Chronic sinus infection; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.72 0.39 1.26e-13 Prudent dietary pattern; LIHC cis rs4242434 0.927 rs3736147 chr8:22471824 A/G cg14690197 chr8:22456421 C8orf58 -0.42 -6.27 -0.32 1.07e-9 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg11890956 chr21:40555474 PSMG1 1.0 14.18 0.61 3.28e-36 Cognitive function; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20349687 chr2:88927127 EIF2AK3 -0.48 -6.18 -0.32 1.86e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12477438 0.501 rs11123770 chr2:99825102 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.6 9.27 0.45 2.14e-18 Chronic sinus infection; LIHC cis rs11039216 1 rs11039216 chr11:47406592 C/T cg20307385 chr11:47447363 PSMC3 0.76 11.46 0.53 5.87e-26 Neuroticism; LIHC cis rs2976388 0.578 rs3758081 chr8:143824373 A/G cg06565975 chr8:143823917 SLURP1 -0.45 -8.33 -0.41 1.96e-15 Urinary tract infection frequency; LIHC cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg15691649 chr6:25882328 NA -0.51 -7.43 -0.37 8.62e-13 Blood metabolite levels; LIHC cis rs11734570 0.581 rs4401459 chr4:38585268 G/T cg18361445 chr4:38666374 KLF3;FLJ13197 -0.46 -6.36 -0.33 6.48e-10 Inflammatory bowel disease;Crohn's disease; LIHC trans rs1814175 0.708 rs10839464 chr11:49981386 T/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs11098499 0.954 rs17046116 chr4:120387259 G/A cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs4478037 0.822 rs9868526 chr3:33124269 A/G cg27203090 chr3:33138513 GLB1;TMPPE 0.52 6.53 0.33 2.31e-10 Major depressive disorder; LIHC cis rs2242116 0.760 rs4682845 chr3:46955404 G/C cg23352942 chr3:46931381 PTH1R -0.28 -7.16 -0.36 4.99e-12 Birth weight; LIHC cis rs11958404 0.615 rs10475649 chr5:157447301 T/C cg05962755 chr5:157440814 NA 0.59 7.83 0.39 6.15e-14 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19877205 chr20:52824603 PFDN4 -0.4 -6.13 -0.31 2.43e-9 Pancreatic cancer; LIHC cis rs2404602 0.575 rs11072611 chr15:76947983 A/G cg03037974 chr15:76606532 NA 0.49 7.74 0.39 1.13e-13 Blood metabolite levels; LIHC cis rs1023500 0.596 rs5751209 chr22:42451603 A/G cg15557168 chr22:42548783 NA -0.44 -6.87 -0.35 3.04e-11 Schizophrenia; LIHC cis rs921968 0.541 rs620596 chr2:219462419 G/A cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.63e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs270601 0.837 rs367805 chr5:131701279 T/C cg24060327 chr5:131705240 SLC22A5 -0.77 -11.86 -0.54 2.07e-27 Acylcarnitine levels; LIHC cis rs6089584 1.000 rs3787425 chr20:60559256 C/T cg13770153 chr20:60521292 NA -0.35 -6.9 -0.35 2.53e-11 Body mass index; LIHC cis rs4237845 0.537 rs10747786 chr12:58260601 G/T cg04478727 chr12:58166393 METTL1;FAM119B 0.57 8.02 0.4 1.69e-14 Intelligence (multi-trait analysis); LIHC cis rs763014 0.932 rs2269559 chr16:682297 T/C cg09263875 chr16:632152 PIGQ 0.59 10.28 0.49 8.62e-22 Height; LIHC cis rs3820068 0.705 rs4646031 chr1:15834648 A/G cg17385448 chr1:15911702 AGMAT 0.38 6.7 0.34 8.52e-11 Systolic blood pressure; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg18000306 chr6:288505 NA 0.36 6.91 0.35 2.35e-11 Menopause (age at onset); LIHC cis rs8062405 0.895 rs62036658 chr16:28850371 T/G cg07451762 chr16:28383216 NA 0.34 6.17 0.32 1.9e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1185460 0.967 rs1184902 chr11:118945337 A/G cg23280166 chr11:118938394 VPS11 0.59 7.89 0.39 4.26e-14 Coronary artery disease; LIHC cis rs17095355 1.000 rs11194933 chr10:111725862 T/C cg00817464 chr10:111662876 XPNPEP1 -0.41 -5.96 -0.31 6.19e-9 Biliary atresia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00419759 chr1:114301964 PHTF1 0.41 6.25 0.32 1.23e-9 Pancreatic cancer; LIHC cis rs8017423 0.967 rs8016385 chr14:90721946 G/A cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 2.97e-9 Mortality in heart failure; LIHC cis rs9303280 0.719 rs56750287 chr17:38062944 A/C cg11212589 chr17:38028394 ZPBP2 0.35 7.18 0.36 4.3e-12 Self-reported allergy; LIHC cis rs67478160 0.619 rs1187416 chr14:104311465 A/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.29 0.55 5.2e-29 Schizophrenia; LIHC cis rs7927592 0.913 rs12285993 chr11:68302538 A/G cg20283391 chr11:68216788 NA -0.52 -7.8 -0.39 7.74e-14 Total body bone mineral density; LIHC cis rs9896933 0.830 rs113051447 chr17:80791806 A/G cg15664640 chr17:80829946 TBCD -0.55 -5.86 -0.3 1.1e-8 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg26752003 chr8:145688521 CYHR1 0.5 8.02 0.4 1.69e-14 Age at first birth; LIHC cis rs11122272 0.735 rs2808604 chr1:231538916 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.77e-22 Hemoglobin concentration; LIHC cis rs986417 0.901 rs11158292 chr14:61043183 G/T cg27398547 chr14:60952738 C14orf39 0.82 9.31 0.45 1.55e-18 Gut microbiota (bacterial taxa); LIHC cis rs3008870 0.677 rs2815354 chr1:67483642 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.86 12.93 0.57 2.02e-31 Lymphocyte percentage of white cells; LIHC cis rs614226 1.000 rs614226 chr12:120974510 C/T cg01236616 chr12:121019343 POP5 -1.29 -19.32 -0.72 9.82e-57 Type 1 diabetes nephropathy; LIHC trans rs11088226 0.681 rs2833926 chr21:33975279 A/G cg09050820 chr6:167586206 TCP10L2 0.78 13.16 0.58 2.73e-32 Gastritis; LIHC cis rs992157 1.000 rs6736362 chr2:219115108 C/T cg00012203 chr2:219082015 ARPC2 0.92 15.08 0.63 9.68e-40 Colorectal cancer; LIHC cis rs17106184 1.000 rs12089749 chr1:51306329 C/A cg07174182 chr1:51127561 FAF1 -0.62 -6.59 -0.34 1.68e-10 Type 2 diabetes; LIHC cis rs1707322 0.928 rs6681068 chr1:46398382 G/A cg06784218 chr1:46089804 CCDC17 0.33 5.9 0.3 8.78e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4727027 0.901 rs6943937 chr7:148869915 A/G cg23583168 chr7:148888333 NA -0.72 -10.28 -0.49 9.19e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs208520 0.955 rs28684412 chr6:66979430 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.04 0.36 1.04e-11 Exhaled nitric oxide output; LIHC cis rs2242116 0.793 rs9855938 chr3:46957298 G/A cg27129171 chr3:47204927 SETD2 0.49 7.88 0.39 4.48e-14 Birth weight; LIHC cis rs8078723 0.966 rs2227322 chr17:38171668 C/G cg17344932 chr17:38183730 MED24;SNORD124 -0.56 -9.02 -0.44 1.4e-17 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs61990749 0.597 rs176955 chr14:78181220 C/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.77 -0.39 9.19e-14 Fibroblast growth factor basic levels; LIHC cis rs12188164 0.543 rs890972 chr5:462465 C/A cg26072250 chr5:443457 EXOC3;C5orf55 0.47 7.07 0.36 8.74e-12 Cystic fibrosis severity; LIHC cis rs1506636 1.000 rs1911145 chr7:123363658 A/G cg03229431 chr7:123269106 ASB15 -0.62 -12.58 -0.56 4.45e-30 Plateletcrit;Platelet count; LIHC cis rs9309473 0.950 rs6756885 chr2:73805172 A/G cg20560298 chr2:73613845 ALMS1 -0.57 -6.85 -0.35 3.4e-11 Metabolite levels; LIHC cis rs6809651 0.524 rs10937240 chr3:185802823 C/T cg00760338 chr3:185826511 ETV5 -0.85 -12.67 -0.57 1.93e-30 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs4975616 0.869 rs31490 chr5:1344458 G/A cg06550200 chr5:1325588 CLPTM1L -0.67 -10.63 -0.5 5.43e-23 Lung cancer; LIHC cis rs11758351 0.866 rs56186759 chr6:26207181 C/T cg03785755 chr6:26196794 NA 0.5 5.88 0.3 9.89e-9 Gout;Renal underexcretion gout; LIHC cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg06481639 chr22:41940642 POLR3H 0.61 5.87 0.3 1.02e-8 Vitiligo; LIHC cis rs1580019 0.563 rs34319173 chr7:32585904 G/A cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.07 0.31 3.35e-9 Cognitive ability; LIHC cis rs17401966 0.931 rs61778401 chr1:10426474 G/A cg15208524 chr1:10270712 KIF1B 0.41 6.09 0.31 3.05e-9 Hepatocellular carcinoma; LIHC cis rs2115536 0.967 rs934137 chr15:80211768 T/C cg11839771 chr15:80205821 ST20 -0.31 -6.46 -0.33 3.55e-10 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC trans rs875971 0.628 rs6974355 chr7:65841981 A/G cg26939375 chr7:64535504 NA 0.43 6.59 0.34 1.64e-10 Aortic root size; LIHC cis rs7914558 1.000 rs7077291 chr10:104945751 C/T cg15744005 chr10:104629667 AS3MT -0.38 -8.55 -0.42 4.22e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1577917 0.958 rs12209668 chr6:86566517 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.22 -0.41 4.25e-15 Response to antipsychotic treatment; LIHC cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg07061783 chr6:25882402 NA -0.53 -6.73 -0.34 7.08e-11 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg02951883 chr7:2050386 MAD1L1 -0.63 -9.81 -0.47 3.45e-20 Bipolar disorder and schizophrenia; LIHC cis rs548181 0.536 rs503288 chr11:125461787 C/T cg03464685 chr11:125439445 EI24 -0.89 -9.98 -0.47 9.65e-21 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1862618 0.671 rs832531 chr5:56228401 A/G cg12311346 chr5:56204834 C5orf35 -0.46 -6.29 -0.32 9.69e-10 Initial pursuit acceleration; LIHC cis rs12220238 1.000 rs10824105 chr10:75952881 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.38 0.33 5.76e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs12971120 0.947 rs8083001 chr18:72165058 A/G cg25817165 chr18:72167213 CNDP2 -0.66 -12.61 -0.56 3.33e-30 Refractive error; LIHC cis rs420259 0.681 rs249868 chr16:23666797 A/G cg05131483 chr16:23706242 ERN2 0.34 5.8 0.3 1.55e-8 Bipolar disorder; LIHC cis rs9916302 0.861 rs33933929 chr17:37426441 A/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.46 -0.59 2.02e-33 Glomerular filtration rate (creatinine); LIHC cis rs1577917 0.958 rs12208227 chr6:86670944 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.04 -0.48 5.74e-21 Response to antipsychotic treatment; LIHC cis rs6815814 0.950 rs9306967 chr4:38807911 G/C cg06935464 chr4:38784597 TLR10 0.4 6.54 0.33 2.18e-10 Breast cancer; LIHC cis rs12611088 0.538 rs2599435 chr19:43975299 A/G cg13740135 chr19:44006432 PHLDB3 -0.42 -6.18 -0.32 1.87e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs1005277 0.579 rs9418322 chr10:38377296 G/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs5769765 0.837 rs4824110 chr22:50271631 T/A cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs6456156 0.586 rs12527827 chr6:167469271 C/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.71 -0.43 1.28e-16 Primary biliary cholangitis; LIHC cis rs1000083 0.834 rs2351506 chr5:96585715 A/G ch.5.96698337R chr5:96672581 NA 0.84 6.84 0.35 3.68e-11 Cisplatin-induced ototoxicity; LIHC cis rs9303401 0.659 rs17822807 chr17:56687190 A/C cg10487724 chr17:56770010 TEX14;RAD51C 1.01 14.01 0.6 1.53e-35 Cognitive test performance; LIHC cis rs4148883 0.615 rs2187483 chr4:100134103 G/T cg12011299 chr4:100065546 ADH4 -0.32 -6.34 -0.32 7.31e-10 Alcohol dependence; LIHC trans rs60752752 0.852 rs59678238 chr1:153370659 C/G cg14901121 chr8:98817630 LAPTM4B -0.44 -7.28 -0.37 2.35e-12 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs9430161 0.598 rs34350247 chr1:11034460 A/G cg27631724 chr1:11040367 C1orf127 0.36 6.68 0.34 9.79e-11 Ewing sarcoma; LIHC cis rs4409675 0.576 rs12070659 chr1:28227175 G/A cg23691781 chr1:28212827 C1orf38 0.3 7.34 0.37 1.54e-12 Corneal astigmatism; LIHC cis rs17376456 0.504 rs7702649 chr5:93065149 C/A cg25358565 chr5:93447407 FAM172A 0.81 7.73 0.39 1.19e-13 Diabetic retinopathy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25759457 chr1:172502420 C1orf9 0.42 6.06 0.31 3.55e-9 Pancreatic cancer; LIHC cis rs35883536 0.631 rs2783704 chr1:101040652 T/A cg14515779 chr1:101123966 NA -0.45 -6.38 -0.33 5.67e-10 Monocyte count; LIHC trans rs931812 0.691 rs884488 chr8:101898523 C/G cg20993868 chr7:22813445 NA 0.31 7.78 0.39 8.59e-14 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs9611565 0.503 rs5751156 chr22:42170025 A/G cg03806693 chr22:41940476 POLR3H 0.97 10.17 0.48 2.11e-21 Vitiligo; LIHC cis rs3736594 0.513 rs76013440 chr2:27816315 G/A cg27432699 chr2:27873401 GPN1 0.46 6.69 0.34 9.33e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2204008 0.728 rs11495375 chr12:38282631 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.71 0.5 2.77e-23 Bladder cancer; LIHC cis rs35160687 0.644 rs11676515 chr2:86496057 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.35 5.74 0.3 2.12e-8 Night sleep phenotypes; LIHC cis rs753778 0.570 rs6985866 chr8:142210336 C/T cg18755752 chr8:142205143 DENND3 0.32 5.89 0.3 9.03e-9 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs1707322 1.000 rs785467 chr1:46521559 A/T cg03146154 chr1:46216737 IPP -0.46 -7.27 -0.37 2.52e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9543976 1.000 rs7339146 chr13:76173719 G/A cg01531495 chr13:76123901 UCHL3 -0.49 -5.89 -0.3 9.07e-9 Diabetic retinopathy; LIHC cis rs4920343 0.698 rs851121 chr1:19087765 C/T cg19637330 chr1:19110922 NA 0.33 6.08 0.31 3.28e-9 Knee osteoarthritis; LIHC cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg20607798 chr8:58055168 NA 0.69 8.4 0.41 1.18e-15 Developmental language disorder (linguistic errors); LIHC cis rs7172677 0.768 rs72730587 chr15:75358053 A/G cg09165964 chr15:75287851 SCAMP5 0.47 6.86 0.35 3.14e-11 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs66887589 0.616 rs7659403 chr4:120207254 T/A cg09307838 chr4:120376055 NA 0.53 7.83 0.39 5.99e-14 Diastolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05379784 chr14:74111382 DNAL1 0.44 6.66 0.34 1.11e-10 Cognitive function; LIHC cis rs9517320 0.534 rs61971163 chr13:99188883 G/A cg07423050 chr13:99094983 FARP1 -0.51 -8.91 -0.43 2.98e-17 Longevity; LIHC cis rs7395581 0.918 rs1449627 chr11:47290984 T/G cg25783544 chr11:47291846 MADD 0.43 6.27 0.32 1.1e-9 HDL cholesterol; LIHC cis rs7188697 0.922 rs37061 chr16:58566671 A/G cg02549819 chr16:58548995 SETD6 -0.45 -7.16 -0.36 5.04e-12 QT interval; LIHC cis rs68170813 0.559 rs17427849 chr7:106864237 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs712039 0.652 rs829161 chr17:35763863 C/T cg16670864 chr17:35848621 DUSP14 -0.36 -6.01 -0.31 4.86e-9 Tuberculosis; LIHC cis rs7707921 0.522 rs12374541 chr5:81491408 A/G cg15871215 chr5:81402204 ATG10 0.61 8.27 0.41 2.92e-15 Breast cancer; LIHC cis rs6967414 0.579 rs6968879 chr7:6757886 T/G cg00387323 chr7:6746715 ZNF12 0.67 7.47 0.37 6.89e-13 Hematocrit;Hemoglobin concentration; LIHC cis rs17384381 0.953 rs12120551 chr1:85810903 T/C cg16011679 chr1:85725395 C1orf52 0.79 8.15 0.4 6.92e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs16828019 0.852 rs12045171 chr1:41528805 G/A cg03962019 chr1:41807865 NA 0.49 7.32 0.37 1.81e-12 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs9829800 chr3:40443927 T/C cg16822855 chr3:40428330 ENTPD3 0.34 6.16 0.32 1.99e-9 Renal cell carcinoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01261044 chr14:35451962 SRP54 0.41 6.38 0.33 5.64e-10 Cognitive function; LIHC cis rs400736 0.671 rs2131630 chr1:7990367 G/A cg25007680 chr1:8021821 PARK7 -0.43 -6.75 -0.34 6.46e-11 Response to antidepressants and depression; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg26338869 chr17:61819248 STRADA 0.61 8.85 0.43 4.64e-17 Prudent dietary pattern; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg08989290 chr16:615782 NHLRC4 0.31 6.12 0.31 2.53e-9 Height; LIHC cis rs1005277 0.505 rs7917943 chr10:38195811 T/A cg25427524 chr10:38739819 LOC399744 0.65 12.6 0.56 3.58e-30 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg02290350 chr8:58132656 NA 0.4 8.41 0.41 1.15e-15 Developmental language disorder (linguistic errors); LIHC cis rs2073300 1.000 rs6137960 chr20:23442886 G/A cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6500602 0.647 rs4785967 chr16:4523208 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.48 6.68 0.34 9.58e-11 Schizophrenia; LIHC cis rs763121 0.853 rs5750621 chr22:38956166 C/T cg21395723 chr22:39101663 GTPBP1 0.38 5.91 0.3 8.27e-9 Menopause (age at onset); LIHC cis rs8077889 0.956 rs116979403 chr17:41849105 G/A cg26893861 chr17:41843967 DUSP3 1.01 10.92 0.51 4.9299999999999996e-24 Triglycerides; LIHC cis rs2153535 0.580 rs9405391 chr6:8466548 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs1403694 0.695 rs67173199 chr3:186432858 G/A cg12454167 chr3:186435060 KNG1 0.39 9.09 0.44 7.92e-18 Blood protein levels; LIHC trans rs561341 0.740 rs11080174 chr17:30208521 C/A cg20587970 chr11:113659929 NA 0.54 6.88 0.35 2.9100000000000002e-11 Hip circumference adjusted for BMI; LIHC cis rs4975616 0.686 rs37011 chr5:1348798 A/T cg07493874 chr5:1342172 CLPTM1L -0.63 -9.96 -0.47 1.12e-20 Lung cancer; LIHC cis rs7618501 0.602 rs2240327 chr3:50113034 C/T cg24110177 chr3:50126178 RBM5 -0.49 -7.94 -0.39 2.9e-14 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg20607798 chr8:58055168 NA 0.67 8.37 0.41 1.5e-15 Developmental language disorder (linguistic errors); LIHC cis rs2760061 0.505 rs708109 chr1:228190657 C/T cg02753203 chr1:228287806 NA 0.72 10.39 0.49 3.79e-22 Diastolic blood pressure; LIHC cis rs709400 1.000 rs57218990 chr14:104128007 T/A cg26031613 chr14:104095156 KLC1 1.06 14.16 0.61 3.86e-36 Body mass index; LIHC cis rs3862030 0.720 rs12569526 chr10:104237007 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -7.25 -0.36 2.87e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs11628318 0.515 rs1190343 chr14:103100348 G/A cg12046867 chr14:103022105 NA -0.37 -5.74 -0.3 2.08e-8 Platelet count; LIHC cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg20090690 chr10:134436459 INPP5A 0.46 5.78 0.3 1.69e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1577917 0.958 rs10455448 chr6:86533611 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.75 -0.3 1.96e-8 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.49e-11 Diabetic kidney disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08953461 chr5:157158882 THG1L 0.45 6.86 0.35 3.23e-11 Cognitive function; LIHC cis rs35955747 0.902 rs2413048 chr22:31686102 G/A cg22777020 chr22:31556080 RNF185 -0.49 -5.76 -0.3 1.91e-8 Neutrophil count;Sum basophil neutrophil counts; LIHC trans rs911555 0.692 rs7145753 chr14:103866100 G/A cg17675199 chr6:35436792 RPL10A -0.41 -8.45 -0.42 8.67e-16 Intelligence (multi-trait analysis); LIHC cis rs3106136 0.933 rs34383543 chr4:95163792 T/C cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.05 -0.4 1.37e-14 Capecitabine sensitivity; LIHC cis rs400736 0.562 rs10864331 chr1:8172178 A/G cg25007680 chr1:8021821 PARK7 -0.44 -6.53 -0.33 2.44e-10 Response to antidepressants and depression; LIHC cis rs798554 0.679 rs13230995 chr7:2887284 G/A cg13628971 chr7:2884303 GNA12 0.61 10.41 0.49 3.2e-22 Height; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg15382696 chr6:118971807 C6orf204 0.63 6.37 0.33 6.05e-10 Diastolic blood pressure; LIHC cis rs798502 0.541 rs2644307 chr7:2832973 G/A cg13628971 chr7:2884303 GNA12 0.37 6.07 0.31 3.49e-9 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Inflammatory bowel disease;Waist circumference adjusted for BMI in non-smokers;Ulcerative colitis;Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs743757 0.938 rs2282753 chr3:50436716 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 0.48 6.78 0.34 5.2e-11 Diastolic blood pressure; LIHC cis rs881375 0.967 rs1008382 chr9:123681255 C/G cg14580859 chr9:123691850 NA 0.38 6.6 0.34 1.61e-10 Rheumatoid arthritis; LIHC cis rs2180341 0.920 rs6916990 chr6:127698759 G/A cg24812749 chr6:127587940 RNF146 1.06 16.09 0.66 9.03e-44 Breast cancer; LIHC cis rs7980687 0.596 rs1727319 chr12:123701353 T/C cg05973401 chr12:123451056 ABCB9 0.44 6.03 0.31 4.15e-9 Height;Educational attainment;Head circumference (infant); LIHC cis rs10752881 0.967 rs6695746 chr1:182991355 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.41 0.49 3.15e-22 Colorectal cancer; LIHC cis rs17826219 0.568 rs2626985 chr17:29077437 A/G cg14067834 chr17:29058358 SUZ12P 0.69 6.82 0.35 4.22e-11 Body mass index; LIHC cis rs903552 0.935 rs4965387 chr15:102003209 G/A cg00659931 chr15:102010125 PCSK6 -0.45 -6.15 -0.32 2.2e-9 Diabetic kidney disease; LIHC cis rs6750047 0.625 rs336037 chr2:38261124 T/C cg07380506 chr2:38303506 CYP1B1 -0.59 -7.45 -0.37 7.81e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs919433 0.680 rs788018 chr2:198265526 A/G cg03934865 chr2:198174659 NA 0.54 8.24 0.41 3.72e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9649465 0.561 rs609953 chr7:123422444 T/A cg03229431 chr7:123269106 ASB15 0.43 9.14 0.44 5.59e-18 Migraine; LIHC cis rs6502050 0.835 rs6502069 chr17:80112599 G/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs2540917 0.654 rs11125842 chr2:60640807 A/G cg00543073 chr2:60773386 BCL11A -0.33 -6.5 -0.33 2.85e-10 Mean corpuscular volume; LIHC cis rs1008375 1.000 rs13149474 chr4:17688582 G/A cg16339924 chr4:17578868 LAP3 -0.49 -6.13 -0.31 2.48e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11671005 0.735 rs11670871 chr19:58940514 C/T cg25952890 chr19:58913133 NA -0.7 -7.72 -0.39 1.31e-13 Mean platelet volume; LIHC cis rs17711722 0.583 rs10085415 chr7:65093568 T/A cg11987759 chr7:65425863 GUSB 0.38 5.92 0.3 7.82e-9 Calcium levels; LIHC cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs7085104 0.632 rs7097872 chr10:104606636 C/T cg15744005 chr10:104629667 AS3MT -0.42 -9.62 -0.46 1.5e-19 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.48 0.46 4.54e-19 Electroencephalogram traits; LIHC cis rs757081 0.637 rs34941502 chr11:17155432 G/A cg15432903 chr11:17409602 KCNJ11 -0.42 -5.81 -0.3 1.44e-8 Systolic blood pressure; LIHC cis rs34779708 0.931 rs4934697 chr10:35287192 C/T cg03585969 chr10:35415529 CREM 0.87 13.05 0.58 7.09e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg06873352 chr17:61820015 STRADA 0.69 12.03 0.55 4.8e-28 Prudent dietary pattern; LIHC cis rs739401 0.619 rs10766481 chr11:2961512 G/C cg20651018 chr11:3035856 CARS -0.34 -5.76 -0.3 1.92e-8 Longevity; LIHC cis rs9303401 0.573 rs62081879 chr17:57181524 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.29 0.55 5.1e-29 Cognitive test performance; LIHC cis rs861020 0.771 rs1962735 chr1:210012102 A/G cg09163369 chr1:210001066 C1orf107 0.48 6.28 0.32 1.04e-9 Orofacial clefts; LIHC cis rs1577917 0.727 rs9351065 chr6:86360428 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -8.16 -0.4 6.42e-15 Response to antipsychotic treatment; LIHC cis rs4555082 0.957 rs2816608 chr14:105718407 A/G cg06808227 chr14:105710500 BRF1 0.6 8.36 0.41 1.64e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs11264799 0.520 rs2779159 chr1:157550357 C/T cg18268488 chr1:157545234 FCRL4 0.21 5.73 0.3 2.25e-8 IgA nephropathy; LIHC cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.76 0.3 1.86e-8 Schizophrenia; LIHC cis rs72781680 0.898 rs72781639 chr2:24204148 C/G cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs12579753 1.000 rs12830268 chr12:82233627 A/C cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs4555082 0.834 rs2735822 chr14:105712734 C/T cg13114125 chr14:105738426 BRF1 -0.81 -10.46 -0.49 2.15e-22 Mean platelet volume;Platelet distribution width; LIHC cis rs9814567 1.000 rs9828815 chr3:134265749 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9916302 0.861 rs4795377 chr17:37669056 C/T cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC cis rs2033711 0.870 rs4801583 chr19:58918405 A/G cg00825309 chr19:58991885 ZNF446 -0.63 -9.62 -0.46 1.47e-19 Uric acid clearance; LIHC cis rs11098499 0.954 rs11935596 chr4:120412457 G/C cg09307838 chr4:120376055 NA 0.77 12.34 0.56 3.42e-29 Corneal astigmatism; LIHC cis rs6963495 0.649 rs1706888 chr7:105149176 A/G cg19920283 chr7:105172520 RINT1 0.48 6.13 0.31 2.49e-9 Bipolar disorder (body mass index interaction); LIHC cis rs921968 0.541 rs496674 chr2:219432569 G/A cg02985541 chr2:219472218 PLCD4 0.42 6.84 0.35 3.73e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9372253 1.000 rs9372253 chr6:110716136 C/T cg19196401 chr6:110721138 DDO -0.32 -6.38 -0.33 5.82e-10 Platelet distribution width; LIHC cis rs9457247 0.935 rs1044059 chr6:167369897 C/A cg23791538 chr6:167370224 RNASET2 0.69 11.6 0.53 1.81e-26 Crohn's disease; LIHC trans rs1973993 0.567 rs2800431 chr1:97000998 C/T cg10631902 chr5:14652156 NA 0.35 8.26 0.41 3.19e-15 Weight; LIHC cis rs600806 0.850 rs10776806 chr1:109952127 G/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.13 -0.36 6.2e-12 Intelligence (multi-trait analysis); LIHC cis rs17854409 0.803 rs1048109 chr20:61472120 G/A cg06598544 chr20:61472147 COL9A3 -0.9 -8.42 -0.41 1.07e-15 Obesity-related traits; LIHC cis rs9911578 0.902 rs12948746 chr17:57071892 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -9.03 -0.44 1.24e-17 Intelligence (multi-trait analysis); LIHC cis rs11690935 0.959 rs6722757 chr2:172591963 A/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.75 -0.69 2.03e-50 Schizophrenia; LIHC cis rs1023500 0.596 rs5751209 chr22:42451603 A/G cg00645731 chr22:42541494 CYP2D7P1 0.41 6.35 0.32 7.02e-10 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16189954 chr22:29138267 HSCB;CHEK2 0.42 6.19 0.32 1.71e-9 Pancreatic cancer; LIHC cis rs4934494 0.768 rs12572608 chr10:91406927 A/G cg19698084 chr10:91461284 KIF20B 0.49 6.53 0.33 2.4e-10 Red blood cell count; LIHC cis rs7224685 0.569 rs7213885 chr17:4018489 T/A cg11204139 chr17:3907470 NA 0.57 6.62 0.34 1.36e-10 Type 2 diabetes; LIHC cis rs2070488 0.775 rs4371464 chr3:38548021 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.7 -11.49 -0.53 4.66e-26 Electrocardiographic conduction measures; LIHC cis rs7829975 0.623 rs10087493 chr8:8373557 A/G cg08975724 chr8:8085496 FLJ10661 -0.37 -5.98 -0.31 5.66e-9 Mood instability; LIHC cis rs911119 1.000 rs71334202 chr20:23618652 A/C cg16589663 chr20:23618590 CST3 0.76 8.18 0.4 5.78e-15 Chronic kidney disease; LIHC cis rs17854409 1.000 rs17854409 chr20:61491494 T/C cg07645718 chr20:61493192 TCFL5 0.75 6.14 0.32 2.31e-9 Obesity-related traits; LIHC cis rs2032447 0.530 rs9356996 chr6:26008487 C/A cg03517284 chr6:25882590 NA -0.5 -6.46 -0.33 3.66e-10 Intelligence (multi-trait analysis); LIHC cis rs9640161 0.830 rs17173681 chr7:150059414 A/G cg21361702 chr7:150065534 REPIN1 -0.54 -7.66 -0.38 1.95e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs727563 0.594 rs5758408 chr22:42077737 A/C cg06634786 chr22:41940651 POLR3H 0.71 7.37 0.37 1.27e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs12200782 0.530 rs9379892 chr6:26582414 G/A cg18867708 chr6:26865862 GUSBL1 0.48 5.84 0.3 1.22e-8 Small cell lung carcinoma; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs3106136 0.967 rs3113862 chr4:95143122 A/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.06 -0.4 1.31e-14 Capecitabine sensitivity; LIHC cis rs7208859 0.673 rs56085216 chr17:29217234 T/C cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7091068 0.566 rs7082701 chr10:95501042 G/T cg20715218 chr10:95462985 C10orf4 0.57 5.86 0.3 1.07e-8 Urinary tract infection frequency; LIHC cis rs7903847 0.620 rs17112674 chr10:99122178 C/T cg08345082 chr10:99160200 RRP12 0.39 6.81 0.35 4.47e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs9513627 0.833 rs73556146 chr13:100116920 A/G cg25919922 chr13:100150906 NA -0.75 -6.36 -0.32 6.66e-10 Obesity-related traits; LIHC cis rs11676348 0.901 rs7562334 chr2:219003360 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.42 -5.79 -0.3 1.58e-8 Ulcerative colitis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg00715988 chr14:96968640 PAPOLA -0.46 -6.79 -0.34 4.95e-11 Systolic blood pressure; LIHC cis rs1018836 0.770 rs12543806 chr8:91664011 C/T cg16814680 chr8:91681699 NA -0.88 -14.62 -0.62 6.16e-38 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs57590327 0.679 rs35942842 chr3:81588362 G/A cg07356753 chr3:81810745 GBE1 -0.47 -6.43 -0.33 4.29e-10 Extraversion; LIHC cis rs644799 1.000 rs505220 chr11:95563228 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg06238570 chr21:40685208 BRWD1 0.61 7.29 0.37 2.11e-12 Cognitive function; LIHC trans rs6058796 1.000 rs9636547 chr20:31262033 T/A cg02600331 chr11:130417168 NA 0.36 7.86 0.39 4.98e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs6977660 1.000 rs13230910 chr7:19806003 A/G cg07541023 chr7:19748670 TWISTNB -0.39 -6.09 -0.31 3.05e-9 Thyroid stimulating hormone; LIHC cis rs9916302 0.904 rs6503503 chr17:37514373 G/A cg03013999 chr17:37608204 MED1 -0.34 -5.76 -0.3 1.91e-8 Glomerular filtration rate (creatinine); LIHC cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg27211696 chr2:191398769 TMEM194B 0.66 10.95 0.51 4.11e-24 Pulse pressure; LIHC cis rs2070488 1.000 rs13079757 chr3:38491444 C/T cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC cis rs875971 0.862 rs6460290 chr7:65809106 G/A cg11764359 chr7:65958608 NA -0.85 -15.09 -0.63 8.79e-40 Aortic root size; LIHC cis rs4253772 0.744 rs1134224 chr22:46633371 A/T cg09491104 chr22:46646882 C22orf40 -0.61 -6.96 -0.35 1.78e-11 LDL cholesterol;Cholesterol, total; LIHC cis rs12986413 0.967 rs1015670 chr19:2171490 G/A cg09261902 chr19:2140048 AP3D1 0.37 6.38 0.33 5.85e-10 Height; LIHC cis rs11098499 0.575 rs907204 chr4:120238654 G/A cg09307838 chr4:120376055 NA 0.71 11.01 0.51 2.43e-24 Corneal astigmatism; LIHC cis rs1728785 1.000 rs7202306 chr16:68587684 G/A cg02972257 chr16:68554789 NA -0.53 -5.93 -0.31 7.57e-9 Ulcerative colitis; LIHC cis rs6582630 0.638 rs10880644 chr12:38554959 G/A cg26384229 chr12:38710491 ALG10B 0.39 5.93 0.31 7.38e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7843479 0.601 rs878873 chr8:21834581 T/C cg17168535 chr8:21777572 XPO7 0.59 10.37 0.49 4.3e-22 Mean corpuscular volume; LIHC cis rs9311474 0.607 rs34005367 chr3:52558904 A/T cg10802521 chr3:52805072 NEK4 -0.4 -6.53 -0.33 2.34e-10 Electroencephalogram traits; LIHC cis rs6061231 0.701 rs6061505 chr20:60960211 G/A cg24112000 chr20:60950667 NA -0.6 -9.72 -0.47 6.86e-20 Colorectal cancer; LIHC cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg03264133 chr6:25882463 NA -0.7 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg02475777 chr4:1388615 CRIPAK 0.52 7.55 0.38 4.12e-13 Longevity; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg19362124 chr8:42912008 FNTA -0.4 -6.47 -0.33 3.35e-10 Eotaxin levels; LIHC cis rs6938 0.534 rs12907898 chr15:75207872 C/T cg14664628 chr15:75095509 CSK -0.5 -6.54 -0.33 2.21e-10 Breast cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06503243 chr13:42006994 OR7E37P 0.36 6.15 0.32 2.22e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs1144333 0.655 rs76992868 chr1:76418916 G/A cg10154597 chr10:134910271 GPR123 0.31 6.11 0.31 2.69e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg03452623 chr4:187889614 NA -0.32 -8.29 -0.41 2.68e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs2857078 0.654 rs4793083 chr17:42312973 C/T cg13607699 chr17:42295918 UBTF -0.62 -11.07 -0.51 1.49e-24 Red cell distribution width;Reticulocyte count; LIHC cis rs10744422 0.800 rs839363 chr12:123276924 C/T cg07706471 chr12:123319906 HIP1R -0.6 -7.65 -0.38 2.02e-13 Schizophrenia; LIHC cis rs6840360 0.615 rs7669761 chr4:152609304 G/A cg22705602 chr4:152727874 NA -0.33 -7.05 -0.36 1.01e-11 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.673 rs73271887 chr17:29154935 T/C cg14067834 chr17:29058358 SUZ12P 0.69 6.72 0.34 7.71e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs61990749 0.597 rs176971 chr14:78191599 T/G cg23188588 chr14:78226832 SNW1;C14orf178 0.63 10.36 0.49 4.71e-22 Fibroblast growth factor basic levels; LIHC cis rs911119 0.909 rs3761279 chr20:23620075 C/G cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs763121 0.853 rs138709 chr22:39139216 C/G cg06022373 chr22:39101656 GTPBP1 0.71 13.67 0.59 3.13e-34 Menopause (age at onset); LIHC cis rs6738485 0.507 rs66569888 chr2:106886967 G/A cg23109721 chr2:106886537 NA -0.73 -7.03 -0.36 1.13e-11 Pursuit maintenance gain;Pursuit maintenance gain in psychotic disorders; LIHC cis rs6570726 0.846 rs1935616 chr6:145943512 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.5 0.53 4.37e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs1580019 0.961 rs766657 chr7:32499510 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.78 11.95 0.54 9.69e-28 Cognitive ability; LIHC cis rs17685 0.753 rs869806 chr7:75688623 C/T cg04610667 chr7:75704037 NA -0.35 -6.33 -0.32 7.67e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9457247 1.000 rs429083 chr6:167383972 T/C cg23791538 chr6:167370224 RNASET2 -0.67 -11.63 -0.53 1.44e-26 Crohn's disease; LIHC cis rs7312933 0.531 rs2708059 chr12:42851008 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.31 -0.41 2.27e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1707322 0.963 rs6690652 chr1:46376692 G/T cg03146154 chr1:46216737 IPP 0.47 7.66 0.38 1.88e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1443512 0.812 rs1867299 chr12:54329975 T/C cg12374095 chr12:54320830 NA 0.44 6.36 0.33 6.39e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC trans rs875971 1.000 rs875971 chr7:65617595 A/G cg10756647 chr7:56101905 PSPH -0.43 -6.08 -0.31 3.21e-9 Aortic root size; LIHC cis rs7149337 0.836 rs12588488 chr14:51660217 C/A cg23942311 chr14:51606299 NA 0.33 6.7 0.34 8.61e-11 Cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06425136 chr16:31040922 NA -0.41 -6.33 -0.32 7.7e-10 Systolic blood pressure; LIHC cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.08 0.44 9.16e-18 Platelet count; LIHC cis rs28374715 0.662 rs113913466 chr15:41483100 A/G cg18705301 chr15:41695430 NDUFAF1 -0.88 -9.72 -0.47 7.19e-20 Ulcerative colitis; LIHC cis rs10242455 0.557 rs59672032 chr7:99058697 T/C cg18809830 chr7:99032528 PTCD1 -0.79 -6.22 -0.32 1.46e-9 Blood metabolite levels; LIHC cis rs798554 0.959 rs798557 chr7:2758982 G/A cg19346786 chr7:2764209 NA -0.43 -6.34 -0.32 7.41e-10 Height; LIHC cis rs10489202 1.000 rs7538581 chr1:167979347 A/G cg24449463 chr1:168025552 DCAF6 -0.51 -6.4 -0.33 5.12e-10 Schizophrenia; LIHC cis rs79839061 0.610 rs78590562 chr4:869715 C/T cg07828340 chr4:882639 GAK 0.83 7.04 0.36 1.05e-11 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.845 rs7299861 chr12:29409667 G/A cg21522988 chr12:29376872 FAR2 0.3 6.86 0.35 3.28e-11 QT interval; LIHC cis rs7937682 0.883 rs659529 chr11:111436896 T/A cg09085632 chr11:111637200 PPP2R1B -0.91 -10.95 -0.51 3.86e-24 Primary sclerosing cholangitis; LIHC trans rs9302065 0.565 rs2993586 chr13:95962578 T/C cg19955956 chr7:72299837 SBDSP;TYW1B 0.38 7.08 0.36 8.01e-12 Blood metabolite levels; LIHC cis rs941873 0.869 rs7917610 chr10:81117237 T/C cg11057378 chr10:81107060 PPIF 0.37 6.06 0.31 3.63e-9 Height; LIHC cis rs4803468 1.000 rs284651 chr19:41928336 T/C cg09537434 chr19:41945824 ATP5SL -1.03 -21.47 -0.76 2.4e-65 Height; LIHC trans rs7193541 0.646 rs7188880 chr16:74664810 A/T cg23598604 chr1:99732472 LPPR4 -0.31 -6.5 -0.33 2.86e-10 Multiple myeloma; LIHC cis rs9783347 1.000 rs4150564 chr11:18355308 G/A cg15585147 chr11:18324498 HPS5 0.43 6.73 0.34 6.95e-11 Pancreatic cancer; LIHC cis rs17401966 0.965 rs12751375 chr1:10291874 C/G cg15208524 chr1:10270712 KIF1B 0.45 6.53 0.33 2.31e-10 Hepatocellular carcinoma; LIHC cis rs35110281 0.720 rs162394 chr21:44943550 C/G cg04455712 chr21:45112962 RRP1B -0.48 -7.92 -0.39 3.41e-14 Mean corpuscular volume; LIHC cis rs7258465 0.931 rs271629 chr19:18623198 G/A cg10790698 chr19:18539756 SSBP4 -0.34 -7.22 -0.36 3.38e-12 Breast cancer; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.46e-9 Renal cell carcinoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22352273 chr2:238969464 SCLY -0.43 -6.3 -0.32 9.2e-10 Cognitive function; LIHC cis rs8141529 0.748 rs715531 chr22:29282679 A/G cg15103426 chr22:29168792 CCDC117 0.58 9.39 0.45 8.68e-19 Lymphocyte counts; LIHC cis rs2257205 0.667 rs79155614 chr17:56722496 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs7772486 0.558 rs702322 chr6:146007166 G/A cg23711669 chr6:146136114 FBXO30 -0.63 -9.75 -0.47 5.41e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg06618935 chr21:46677482 NA 0.32 6.04 0.31 3.94e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11577318 0.853 rs4450008 chr1:26643860 C/A cg18121669 chr1:26560928 CCDC21 0.51 7.96 0.4 2.58e-14 Granulocyte percentage of myeloid white cells; LIHC trans rs2727020 0.521 rs7930855 chr11:49521660 C/T cg15704280 chr7:45808275 SEPT13 0.8 11.94 0.54 1.04e-27 Coronary artery disease; LIHC cis rs3796352 1.000 rs11713290 chr3:52971579 G/A cg07884673 chr3:53033167 SFMBT1 0.88 6.5 0.33 2.77e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg25894440 chr7:65020034 NA 0.52 6.05 0.31 3.73e-9 Diabetic kidney disease; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg09033563 chr22:24373618 LOC391322 -0.51 -7.05 -0.36 9.75e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2070488 0.930 rs2370840 chr3:38529825 C/T cg24069376 chr3:38537580 EXOG 0.43 8.13 0.4 8.1e-15 Electrocardiographic conduction measures; LIHC cis rs9768139 0.733 rs56205111 chr7:158121055 T/C cg25566285 chr7:158114605 PTPRN2 0.22 6.07 0.31 3.42e-9 Calcium levels; LIHC cis rs2251381 0.750 rs2776250 chr21:30528094 T/G cg08807101 chr21:30365312 RNF160 0.76 10.14 0.48 2.64e-21 Selective IgA deficiency; LIHC cis rs6570726 0.791 rs414297 chr6:145887556 C/T cg13319975 chr6:146136371 FBXO30 -0.36 -5.99 -0.31 5.26e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.540 rs736270 chr7:65428822 T/C cg14393609 chr7:65229607 NA 0.44 6.57 0.33 1.84e-10 Aortic root size; LIHC cis rs1046896 0.739 rs2379358 chr17:80741612 G/A cg22325292 chr17:80708367 FN3K 0.39 6.27 0.32 1.08e-9 Glycated hemoglobin levels; LIHC cis rs916888 0.821 rs199509 chr17:44858728 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg09455208 chr3:40491958 NA 0.39 7.78 0.39 8.72e-14 Renal cell carcinoma; LIHC trans rs9951602 0.512 rs12607561 chr18:76644284 G/A cg02800362 chr5:177631904 HNRNPAB 0.64 10.24 0.48 1.24e-21 Obesity-related traits; LIHC cis rs7100689 0.622 rs4933378 chr10:82147057 T/C cg01528321 chr10:82214614 TSPAN14 0.85 12.01 0.54 5.59e-28 Post bronchodilator FEV1; LIHC cis rs8062405 0.723 rs113208333 chr16:28606160 G/T cg07382826 chr16:28625726 SULT1A1 0.52 8.01 0.4 1.82e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.25 -0.45 2.55e-18 Bipolar disorder; LIHC cis rs4555082 0.874 rs2816613 chr14:105726367 C/T cg10792982 chr14:105748885 BRF1 0.45 6.03 0.31 4.22e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg21448741 chr8:58168803 NA 0.36 6.29 0.32 9.57e-10 Developmental language disorder (linguistic errors); LIHC cis rs1728785 1.000 rs1170443 chr16:68573295 G/C cg02972257 chr16:68554789 NA -0.56 -6.45 -0.33 3.89e-10 Ulcerative colitis; LIHC cis rs3806843 0.735 rs801185 chr5:140068869 A/G cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2952156 0.920 rs732084 chr17:37834357 A/C cg00129232 chr17:37814104 STARD3 -0.53 -10.18 -0.48 1.95e-21 Asthma; LIHC cis rs2303759 1.000 rs2303759 chr19:49869051 T/G cg22590775 chr19:49891494 CCDC155 0.47 7.78 0.39 8.57e-14 Multiple sclerosis; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg14552441 chr12:4650518 RAD51AP1 0.36 6.09 0.31 2.99e-9 Hepatitis; LIHC cis rs72627509 0.904 rs781663 chr4:57781754 A/G cg26694713 chr4:57773883 REST 0.73 10.54 0.5 1.1e-22 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs7618501 0.602 rs2013208 chr3:50129399 C/T cg21659725 chr3:3221576 CRBN -0.66 -10.49 -0.49 1.71e-22 Intelligence (multi-trait analysis); LIHC cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.14 -0.31 2.34e-9 Aortic root size; LIHC cis rs3820068 0.581 rs6669417 chr1:15922371 G/T cg17385448 chr1:15911702 AGMAT 0.35 6.23 0.32 1.4e-9 Systolic blood pressure; LIHC cis rs9443189 0.570 rs504323 chr6:76294965 A/G cg01950844 chr6:76311363 SENP6 -0.87 -10.73 -0.5 2.32e-23 Prostate cancer; LIHC cis rs17685 0.712 rs4732578 chr7:75721532 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.76e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11098499 0.909 rs28632018 chr4:120386730 T/C cg09307838 chr4:120376055 NA 0.77 11.98 0.54 7.27e-28 Corneal astigmatism; LIHC cis rs2115536 0.640 rs934134 chr15:80168218 T/C cg00225070 chr15:80189496 MTHFS 0.45 7.42 0.37 9.31e-13 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg12311346 chr5:56204834 C5orf35 -0.57 -7.41 -0.37 9.72e-13 Initial pursuit acceleration; LIHC cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg00612595 chr21:47717864 NA -0.35 -5.76 -0.3 1.85e-8 Testicular germ cell tumor; LIHC cis rs11792861 0.816 rs72607157 chr9:111748001 T/G cg05043794 chr9:111880884 C9orf5 -0.3 -7.07 -0.36 8.93e-12 Menarche (age at onset); LIHC cis rs77637988 0.516 rs55744465 chr2:48632455 G/T cg15846641 chr2:48541264 FOXN2 0.5 6.53 0.33 2.41e-10 Joint mobility (Beighton score); LIHC cis rs4308124 0.708 rs2137168 chr2:111986509 C/T cg04571233 chr2:111982156 NA -0.52 -6.33 -0.32 7.91e-10 Vitiligo; LIHC cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg03060546 chr3:49711283 APEH 0.41 6.16 0.32 2e-9 Menarche (age at onset); LIHC cis rs743757 1.000 rs762897 chr3:50428766 C/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.46 6.93 0.35 2.16e-11 Diastolic blood pressure; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 8.89e-15 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs2808586 chr1:231515559 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs2412488 0.893 rs6825364 chr4:54340881 T/C cg22241045 chr4:54363911 LNX1 -0.41 -6.59 -0.34 1.71e-10 DNA methylation (variation); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01297674 chr2:122406765 CLASP1 0.49 6.72 0.34 7.54e-11 Pancreatic cancer; LIHC cis rs12497850 0.931 rs7623023 chr3:48914238 G/A cg06212747 chr3:49208901 KLHDC8B 0.57 7.39 0.37 1.11e-12 Parkinson's disease; LIHC cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg22800045 chr5:56110881 MAP3K1 0.66 8.41 0.41 1.12e-15 Initial pursuit acceleration; LIHC cis rs6426558 0.537 rs2813950 chr1:227426072 A/G cg10327440 chr1:227177885 CDC42BPA -0.41 -6.58 -0.34 1.78e-10 Neutrophil percentage of white cells; LIHC cis rs950169 0.881 rs62029599 chr15:84956565 A/C cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.12e-11 Schizophrenia; LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.47 -6.77 -0.34 5.72e-11 Lymphocyte counts; LIHC cis rs7615952 0.800 rs13086460 chr3:125646417 C/T cg05084668 chr3:125655381 ALG1L -0.6 -8.59 -0.42 3.09e-16 Blood pressure (smoking interaction); LIHC cis rs523522 1.000 rs1563333 chr12:120934407 C/T cg12219531 chr12:120966889 COQ5 0.66 13.04 0.58 7.61e-32 High light scatter reticulocyte count; LIHC cis rs2033711 0.870 rs1465789 chr19:58946056 C/T cg03735888 chr19:58951602 ZNF132 0.35 5.76 0.3 1.83e-8 Uric acid clearance; LIHC cis rs10911251 0.546 rs2027081 chr1:183074576 A/G ch.1.3577855R chr1:183094577 LAMC1 0.63 11.02 0.51 2.36e-24 Colorectal cancer; LIHC cis rs780094 0.564 rs4665978 chr2:27648726 T/C cg05484376 chr2:27715224 FNDC4 0.35 5.8 0.3 1.49e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs6754311 0.731 rs2322660 chr2:136557319 A/G cg07305463 chr2:136567211 LCT -0.4 -7.68 -0.38 1.65e-13 Mosquito bite size; LIHC trans rs1945213 0.694 rs1384099 chr11:55866040 A/C cg03929089 chr4:120376271 NA 0.55 7.25 0.36 2.82e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs2073300 0.609 rs6137945 chr20:23406136 C/T cg16736954 chr20:23401023 NAPB 0.72 8.46 0.42 7.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2066819 1.000 rs75754909 chr12:56726349 A/G cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs6733011 0.508 rs6542843 chr2:99533729 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.6 -0.34 1.59e-10 Bipolar disorder; LIHC cis rs4906332 1.000 rs13987 chr14:103969909 A/G cg19000871 chr14:103996768 TRMT61A -0.45 -7.52 -0.38 4.95e-13 Coronary artery disease; LIHC cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg03060546 chr3:49711283 APEH 0.39 5.85 0.3 1.15e-8 Menarche (age at onset); LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg20295408 chr7:1910781 MAD1L1 -0.45 -6.49 -0.33 3.03e-10 Bipolar disorder and schizophrenia; LIHC cis rs244293 0.965 rs244311 chr17:53212803 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.37 -0.37 1.27e-12 Menarche (age at onset); LIHC cis rs11690935 1.000 rs11678984 chr2:172535848 T/G cg13550731 chr2:172543902 DYNC1I2 0.94 19.01 0.72 1.66e-55 Schizophrenia; LIHC trans rs7374732 0.692 rs6800955 chr3:23139179 C/T cg19691163 chr5:96304288 LNPEP 0.42 6.45 0.33 3.8e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI;Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg05025164 chr4:1340916 KIAA1530 0.75 11.61 0.53 1.73e-26 Longevity; LIHC cis rs1348850 0.918 rs4893966 chr2:178470138 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.67 9.94 0.47 1.3e-20 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs933688 0.536 rs332537 chr5:90794973 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.8 -12.29 -0.55 5.27e-29 Smoking behavior; LIHC cis rs8067545 0.641 rs1638525 chr17:19848594 G/C cg13482628 chr17:19912719 NA 0.42 7.06 0.36 9.53e-12 Schizophrenia; LIHC cis rs7520050 0.807 rs72688483 chr1:46149209 A/G cg03146154 chr1:46216737 IPP 0.5 8.34 0.41 1.86e-15 Red blood cell count;Reticulocyte count; LIHC cis rs904251 0.504 rs1757188 chr6:37483808 A/G cg25019722 chr6:37503610 NA -0.32 -5.74 -0.3 2.14e-8 Cognitive performance; LIHC cis rs801193 1.000 rs2003301 chr7:66147656 G/C cg18876405 chr7:65276391 NA -0.43 -7.55 -0.38 3.92e-13 Aortic root size; LIHC cis rs2637266 0.685 rs7098713 chr10:78452828 C/T cg18941641 chr10:78392320 NA 0.27 5.87 0.3 1.02e-8 Pulmonary function; LIHC cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg16606324 chr3:10149918 C3orf24 0.54 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs2576037 0.583 rs478820 chr18:44397782 G/A cg19077165 chr18:44547161 KATNAL2 -0.47 -7.09 -0.36 7.66e-12 Personality dimensions; LIHC cis rs2806561 0.704 rs2868573 chr1:23508253 C/G cg12483005 chr1:23474871 LUZP1 0.46 7.33 0.37 1.66e-12 Height; LIHC cis rs17310467 0.541 rs764598 chr20:33161150 C/G cg08999081 chr20:33150536 PIGU 0.56 5.84 0.3 1.24e-8 Hemostatic factors and hematological phenotypes; LIHC cis rs9359856 0.564 rs76069351 chr6:90425043 C/T cg13799429 chr6:90582589 CASP8AP2 -0.65 -5.84 -0.3 1.18e-8 Bipolar disorder; LIHC cis rs9790314 0.586 rs35713426 chr3:161131271 A/G cg17135325 chr3:160939158 NMD3 0.5 7.46 0.37 7.22e-13 Morning vs. evening chronotype; LIHC cis rs2153535 0.580 rs9392224 chr6:8472614 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs262150 0.544 rs2428780 chr7:158812471 T/A cg19418458 chr7:158789849 NA -0.41 -6.73 -0.34 7.25e-11 Facial morphology (factor 20); LIHC cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg25894440 chr7:65020034 NA -0.55 -6.21 -0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs16828019 0.852 rs11209531 chr1:41571021 C/T cg03387723 chr1:41708464 SCMH1 -0.42 -6.93 -0.35 2.14e-11 Intelligence (multi-trait analysis); LIHC cis rs10089 1.000 rs13357268 chr5:127423051 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.79 0.34 4.83e-11 Ileal carcinoids; LIHC cis rs79057730 0.599 rs6951032 chr7:794092 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.84 9.17 0.44 4.43e-18 Initial pursuit acceleration; LIHC cis rs6435862 0.636 rs717548 chr2:215676905 G/A cg04004882 chr2:215674386 BARD1 -0.61 -9.53 -0.46 2.99e-19 Neuroblastoma (high-risk); LIHC cis rs2439831 1.000 rs2467740 chr15:43746792 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.94 0.44 2.42e-17 Lung cancer in ever smokers; LIHC cis rs911119 1.000 rs73318135 chr20:23618571 T/G cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC trans rs1814175 0.817 rs28594987 chr11:50045181 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.71 -0.79 3.38e-74 Height; LIHC cis rs1577917 0.917 rs12665464 chr6:86574133 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.07 -0.4 1.22e-14 Response to antipsychotic treatment; LIHC cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg08888203 chr3:10149979 C3orf24 0.62 6.86 0.35 3.31e-11 Alzheimer's disease; LIHC cis rs9814567 1.000 rs4955485 chr3:134295843 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.93 -0.31 7.23e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14978174 chr3:156391939 TIPARP;LOC100287227 0.46 6.23 0.32 1.4e-9 Pancreatic cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09604110 chr6:116422028 NT5DC1 -0.39 -6.19 -0.32 1.74e-9 Pancreatic cancer; LIHC cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg06453172 chr10:134556979 INPP5A -0.64 -8.17 -0.4 6.07e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3806843 0.735 rs702394 chr5:140086786 A/G cg19875535 chr5:140030758 IK -0.41 -6.77 -0.34 5.46e-11 Depressive symptoms (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06130371 chr15:65578830 PARP16 -0.42 -6.38 -0.33 5.75e-10 Pancreatic cancer; LIHC cis rs2075371 0.863 rs1646635 chr7:134006728 T/C cg11752832 chr7:134001865 SLC35B4 0.42 6.38 0.33 5.61e-10 Mean platelet volume; LIHC cis rs2204008 0.683 rs12370288 chr12:38127740 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.76 0.3 1.88e-8 Bladder cancer; LIHC cis rs67311347 1.000 rs6795475 chr3:40489281 A/G cg24209194 chr3:40518798 ZNF619 0.49 7.36 0.37 1.37e-12 Renal cell carcinoma; LIHC cis rs2050392 0.858 rs306583 chr10:30710057 C/T cg25182066 chr10:30743637 MAP3K8 0.42 6.9 0.35 2.56e-11 Inflammatory bowel disease; LIHC cis rs1005277 0.579 rs2505196 chr10:38393563 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs240764 0.658 rs4840147 chr6:101182323 T/C cg12253828 chr6:101329408 ASCC3 -0.39 -5.97 -0.31 6.04e-9 Neuroticism; LIHC cis rs7312933 1.000 rs11181328 chr12:42504679 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.95 0.35 1.9e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9916302 0.904 rs801420 chr17:37466103 C/G cg03013999 chr17:37608204 MED1 -0.36 -6.07 -0.31 3.33e-9 Glomerular filtration rate (creatinine); LIHC cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg16606324 chr3:10149918 C3orf24 0.49 5.86 0.3 1.11e-8 Alzheimer's disease; LIHC trans rs875971 0.508 rs10242423 chr7:66059175 A/G cg26939375 chr7:64535504 NA -0.43 -7.32 -0.37 1.77e-12 Aortic root size; LIHC cis rs34172651 0.874 rs200534 chr16:24752641 G/A cg00339695 chr16:24857497 SLC5A11 -0.55 -8.51 -0.42 5.47e-16 Intelligence (multi-trait analysis); LIHC cis rs911119 0.913 rs6036465 chr20:23588003 G/T cg16589663 chr20:23618590 CST3 0.68 7.33 0.37 1.66e-12 Chronic kidney disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01074676 chr14:60601069 C14orf135 0.3 6.57 0.33 1.89e-10 Cognitive function; LIHC cis rs4919087 0.926 rs953097 chr10:98981914 T/C cg25902810 chr10:99078978 FRAT1 0.64 9.41 0.45 7.22e-19 Monocyte count; LIHC cis rs10411936 0.682 rs8103805 chr19:16598433 T/G cg10248733 chr19:16607483 C19orf44;CALR3 0.52 6.95 0.35 1.81e-11 White blood cell count;Multiple sclerosis; LIHC cis rs9902453 0.904 rs4547389 chr17:28364768 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs1997103 1.000 rs6953509 chr7:55412179 G/A cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs743757 1.000 rs2236973 chr3:50474284 T/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.45 6.37 0.33 6.08e-10 Diastolic blood pressure; LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.93 0.39 3.18e-14 Height; LIHC cis rs6674970 0.627 rs2864700 chr1:151028929 C/T cg03258749 chr1:151040405 MLLT11 -0.39 -6.4 -0.33 5.14e-10 Childhood ear infection; LIHC cis rs4474465 1.000 rs2063727 chr11:78183882 T/A cg27205649 chr11:78285834 NARS2 -0.38 -5.78 -0.3 1.68e-8 Alzheimer's disease (survival time); LIHC cis rs11958404 0.932 rs72816592 chr5:157435246 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs11122272 0.735 rs2474633 chr1:231486989 A/C cg06096015 chr1:231504339 EGLN1 0.5 9.22 0.45 3.12e-18 Hemoglobin concentration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12922032 chr2:32582209 BIRC6 0.49 6.49 0.33 3.1e-10 Lung function (FEV1/FVC); LIHC cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.21e-8 Menopause (age at onset); LIHC cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg12463550 chr7:65579703 CRCP 0.69 7.15 0.36 5.29e-12 Diabetic kidney disease; LIHC cis rs9309473 1.000 rs10193972 chr2:73717656 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.84 -0.35 3.68e-11 Metabolite levels; LIHC cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg22168489 chr12:122356033 WDR66 0.45 6.75 0.34 6.16e-11 Mean corpuscular volume; LIHC cis rs2228479 0.850 rs62054640 chr16:89823157 C/T cg06558623 chr16:89946397 TCF25 0.85 11.67 0.53 1.03e-26 Skin colour saturation; LIHC cis rs7249142 0.549 rs539 chr19:19287802 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.27 -0.32 1.08e-9 IgG glycosylation; LIHC trans rs2727020 0.576 rs12293522 chr11:49558425 T/A cg03929089 chr4:120376271 NA -0.9 -17.95 -0.7 3.1e-51 Coronary artery disease; LIHC trans rs2363709 1.000 rs2363709 chr3:67417105 G/A cg13681781 chr9:139102396 QSOX2 0.81 6.33 0.32 7.66e-10 IgE levels; LIHC trans rs13202860 0.908 rs11752790 chr6:87183280 C/A cg27326224 chr7:950474 ADAP1 -0.57 -6.33 -0.32 7.69e-10 Sexual dysfunction (female); LIHC cis rs6430585 0.697 rs115944351 chr2:136515458 G/A cg07169764 chr2:136633963 MCM6 1.16 16.12 0.66 6.66e-44 Corneal structure; LIHC cis rs798554 0.757 rs1182178 chr7:2873763 G/A cg04166393 chr7:2884313 GNA12 0.47 6.34 0.32 7.12e-10 Height; LIHC cis rs17539620 0.624 rs111484697 chr6:154838903 A/G cg17771515 chr6:154831774 CNKSR3 0.59 6.49 0.33 2.96e-10 Lipoprotein (a) levels; LIHC cis rs651907 0.557 rs7629753 chr3:101371922 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.69 -11.81 -0.54 3.18e-27 Colorectal cancer; LIHC cis rs7197653 0.586 rs55856208 chr16:68324210 A/T cg09835421 chr16:68378352 PRMT7 -0.82 -8.58 -0.42 3.44e-16 Magnesium levels; LIHC trans rs950169 0.545 rs4842841 chr15:84641125 G/A cg24036039 chr1:3397125 ARHGEF16 0.4 6.53 0.33 2.43e-10 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07822143 chr4:146019674 ABCE1;ANAPC10 0.4 6.35 0.32 6.67e-10 Pancreatic cancer; LIHC cis rs2204008 0.749 rs10880692 chr12:38592918 C/G cg26384229 chr12:38710491 ALG10B -0.96 -12.85 -0.57 4.02e-31 Bladder cancer; LIHC cis rs12995491 0.933 rs34366691 chr2:88537451 G/A cg14558114 chr2:88469736 THNSL2 -0.37 -5.82 -0.3 1.32e-8 Response to metformin (IC50); LIHC cis rs950776 0.518 rs4887063 chr15:78839715 C/T cg22563815 chr15:78856949 CHRNA5 -0.35 -6.28 -0.32 1.03e-9 Sudden cardiac arrest; LIHC cis rs12086130 0.892 rs72906860 chr1:51499822 G/A cg07174182 chr1:51127561 FAF1 -0.88 -9.84 -0.47 2.7e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs1461503 0.934 rs7119533 chr11:122832683 A/T cg25161029 chr11:122845972 NA 0.4 6.7 0.34 8.39e-11 Menarche (age at onset); LIHC cis rs9911578 0.935 rs34523895 chr17:57034095 T/C cg05425664 chr17:57184151 TRIM37 -0.55 -8.3 -0.41 2.36e-15 Intelligence (multi-trait analysis); LIHC cis rs6598955 0.543 rs61608823 chr1:26555090 G/A cg04990556 chr1:26633338 UBXN11 0.75 10.59 0.5 7.73e-23 Obesity-related traits; LIHC cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg06481639 chr22:41940642 POLR3H 0.6 5.9 0.3 8.91e-9 Vitiligo; LIHC cis rs8081395 0.836 rs1292061 chr17:57911230 A/G cg02344993 chr17:57696989 CLTC -0.46 -7.57 -0.38 3.5e-13 White blood cell count; LIHC cis rs7662987 0.517 rs2602877 chr4:100039847 T/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC trans rs2288327 0.630 rs16866400 chr2:179448911 G/A cg14011486 chr1:26737247 LIN28 0.46 6.28 0.32 1e-9 Atrial fibrillation; LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.84 0.39 5.82e-14 Height; LIHC cis rs6450176 1.000 rs4588541 chr5:53300640 A/G ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.67 -0.62 3.81e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs3780486 0.522 rs10217770 chr9:33146393 C/A cg04842962 chr6:43655489 MRPS18A 0.8 15.14 0.63 5.42e-40 IgG glycosylation; LIHC cis rs7122539 0.646 rs594313 chr11:66608991 A/G cg24851651 chr11:66362959 CCS 0.34 5.9 0.3 8.89e-9 HIV-1 susceptibility; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07810114 chr1:12018622 PLOD1 0.39 6.32 0.32 8.25e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs10791097 0.694 rs12361892 chr11:130744490 T/G cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg05484376 chr2:27715224 FNDC4 0.37 6.31 0.32 8.8e-10 Total body bone mineral density; LIHC cis rs17685 0.753 rs1639609 chr7:75683581 T/C cg04592579 chr7:75616294 TMEM120A 0.39 6.79 0.34 4.9e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.21e-8 Menopause (age at onset); LIHC cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg23172400 chr8:95962367 TP53INP1 -0.36 -8.05 -0.4 1.43e-14 Type 2 diabetes; LIHC cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg12463550 chr7:65579703 CRCP 0.68 7.09 0.36 7.52e-12 Diabetic kidney disease; LIHC cis rs11122272 0.735 rs2572251 chr1:231514243 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.31 0.45 1.6e-18 Hemoglobin concentration; LIHC cis rs992157 0.735 rs10932765 chr2:219099484 T/C cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.34 0.58 5.8e-33 Colorectal cancer; LIHC cis rs875971 1.000 rs2420820 chr7:66091907 T/C cg11764359 chr7:65958608 NA -0.85 -14.78 -0.62 1.38e-38 Aortic root size; LIHC cis rs4975616 0.869 rs466502 chr5:1325767 C/T cg26373071 chr5:1325741 CLPTM1L -0.34 -5.71 -0.3 2.42e-8 Lung cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14331148 chr19:47551893 TMEM160 -0.46 -6.92 -0.35 2.27e-11 Cognitive function; LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg16132339 chr22:24313637 DDTL;DDT 0.81 16.72 0.67 2.73e-46 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6942756 0.680 rs691555 chr7:129135770 C/T cg02491457 chr7:128862824 NA -0.53 -8.22 -0.41 4.13e-15 White matter hyperintensity burden; LIHC cis rs12291225 0.679 rs4757245 chr11:14297872 A/C cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.18e-31 Sense of smell; LIHC cis rs2204008 0.775 rs3900361 chr12:38238936 A/G cg26384229 chr12:38710491 ALG10B -0.83 -10.62 -0.5 5.97e-23 Bladder cancer; LIHC cis rs155076 1.000 rs261406 chr13:21855854 G/A cg14456004 chr13:21872349 NA -1.13 -12.71 -0.57 1.4e-30 White matter hyperintensity burden; LIHC cis rs546131 0.614 rs35357012 chr11:34793384 C/A cg11058730 chr11:34937778 PDHX;APIP -0.51 -6.23 -0.32 1.4e-9 Lung disease severity in cystic fibrosis; LIHC cis rs476633 0.595 rs11857726 chr15:41530359 G/A cg18705301 chr15:41695430 NDUFAF1 -0.42 -5.82 -0.3 1.36e-8 Glomerular filtration rate (creatinine); LIHC cis rs7772486 0.536 rs9373467 chr6:145955605 C/T cg23711669 chr6:146136114 FBXO30 0.64 9.75 0.47 5.54e-20 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.863 rs1010739 chr4:120463471 C/T cg25214090 chr10:38739885 LOC399744 0.58 9.05 0.44 1.08e-17 Corneal astigmatism; LIHC cis rs1801251 0.929 rs10933409 chr2:233629386 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.24 0.52 3.62e-25 Coronary artery disease; LIHC cis rs249954 0.512 rs34514 chr16:23670597 G/A cg09867953 chr16:23706666 ERN2 0.37 6.19 0.32 1.76e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.12 -0.44 6.77e-18 Bipolar disorder; LIHC cis rs4700695 0.668 rs166180 chr5:65499225 C/T cg21114390 chr5:65439923 SFRS12 -0.56 -7.97 -0.4 2.43e-14 Facial morphology (factor 19); LIHC cis rs2760061 0.598 rs658238 chr1:228121291 A/G cg02753203 chr1:228287806 NA -0.48 -7.68 -0.38 1.67e-13 Diastolic blood pressure; LIHC cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.33 5.96 0.31 6.29e-9 Aortic root size; LIHC cis rs2153535 0.580 rs2184585 chr6:8474168 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs832187 0.629 rs6798742 chr3:63903759 A/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.42 -5.98 -0.31 5.68e-9 Schizophrenia; LIHC trans rs208520 0.526 rs9351542 chr6:66788571 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.05 -20.7 -0.75 2.84e-62 Exhaled nitric oxide output; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg21548813 chr6:291882 DUSP22 -0.56 -7.78 -0.39 8.55e-14 Menopause (age at onset); LIHC cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs7727544 0.684 rs274546 chr5:131699867 A/G cg07395648 chr5:131743802 NA -0.3 -6.38 -0.33 5.67e-10 Blood metabolite levels; LIHC cis rs1008375 0.932 rs9884565 chr4:17655096 A/G cg16339924 chr4:17578868 LAP3 0.42 5.96 0.31 6.4e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3096299 0.503 rs9925045 chr16:89556476 T/C cg02187348 chr16:89574699 SPG7 0.62 9.79 0.47 4.25e-20 Multiple myeloma (IgH translocation); LIHC cis rs11958404 0.615 rs7711271 chr5:157452268 C/G cg05962755 chr5:157440814 NA 0.61 7.93 0.39 3.16e-14 IgG glycosylation; LIHC cis rs1371867 0.846 rs1660323 chr8:101278724 T/A cg06002616 chr8:101225028 SPAG1 -0.35 -5.85 -0.3 1.17e-8 Atrioventricular conduction; LIHC cis rs2204008 0.837 rs11180482 chr12:38235950 G/A cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs611744 0.967 rs666821 chr8:109204313 T/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs875971 0.660 rs10281080 chr7:66042441 T/C cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg00656387 chr3:40428638 ENTPD3 0.41 6.73 0.34 6.96e-11 Renal cell carcinoma; LIHC cis rs748404 0.697 rs473016 chr15:43558823 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.28 0.41 2.8e-15 Lung cancer; LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg06873352 chr17:61820015 STRADA 0.56 8.34 0.41 1.81e-15 Height; LIHC cis rs17685 0.753 rs6951808 chr7:75772413 A/G cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg08280861 chr8:58055591 NA 0.48 5.99 0.31 5.37e-9 Developmental language disorder (linguistic errors); LIHC cis rs4925386 0.681 rs2427296 chr20:60927475 G/A cg24112000 chr20:60950667 NA -0.45 -6.04 -0.31 4.07e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg24531977 chr5:56204891 C5orf35 -0.59 -8.47 -0.42 7.24e-16 Initial pursuit acceleration; LIHC cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.01 -9.98 -0.48 9.07e-21 Platelet count; LIHC cis rs763014 0.932 rs2269560 chr16:682442 A/C cg04709771 chr16:646395 RAB40C 0.46 8.19 0.41 5.1e-15 Height; LIHC cis rs748404 0.697 rs1095389 chr15:43566671 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.68 0.34 9.86e-11 Lung cancer; LIHC cis rs9399135 0.967 rs4896121 chr6:135293645 T/C cg24558204 chr6:135376177 HBS1L 0.41 6.72 0.34 7.67e-11 Red blood cell count; LIHC cis rs3806843 0.838 rs2337514 chr5:140132732 T/C cg19875535 chr5:140030758 IK -0.35 -5.76 -0.3 1.87e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1403694 0.695 rs3774291 chr3:186433471 C/T cg12454167 chr3:186435060 KNG1 0.38 8.91 0.43 3.18e-17 Blood protein levels; LIHC cis rs3796352 0.527 rs11714793 chr3:52924930 A/G cg04865290 chr3:52927548 TMEM110 -0.53 -7.03 -0.36 1.1e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg01238044 chr22:24384105 GSTT1 -0.44 -5.98 -0.31 5.57e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg10802521 chr3:52805072 NEK4 -0.42 -6.88 -0.35 2.85e-11 Bipolar disorder; LIHC cis rs1348850 0.750 rs13031008 chr2:178477114 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.66 8.93 0.43 2.63e-17 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2404602 0.684 rs8029283 chr15:76837140 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.48 -0.46 4.24e-19 Blood metabolite levels; LIHC cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.9 -10.88 -0.51 6.88e-24 Platelet count; LIHC cis rs4243830 0.850 rs12410405 chr1:6581283 C/G cg05709478 chr1:6581295 PLEKHG5 0.46 6.32 0.32 8.07e-10 Body mass index; LIHC cis rs2742417 0.603 rs2673062 chr3:45763635 A/G cg04837898 chr3:45731254 SACM1L -0.52 -8.67 -0.42 1.75e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs72627509 1.000 rs57265257 chr4:57839280 A/T cg26694713 chr4:57773883 REST 0.67 9.34 0.45 1.3e-18 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9649213 0.593 rs6465665 chr7:97934150 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.82 -0.3 1.32e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs34779708 0.733 rs3936503 chr10:35549257 A/G cg03585969 chr10:35415529 CREM -0.76 -11.01 -0.51 2.41e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs8103278 1.000 rs35302007 chr19:46219145 G/C cg11657440 chr19:46296263 DMWD -0.54 -8.53 -0.42 4.7e-16 Coronary artery disease; LIHC cis rs7212590 0.581 rs8070961 chr17:57813168 A/G cg10252138 chr17:58120427 NA -0.62 -6.01 -0.31 4.72e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs2274273 0.868 rs9919926 chr14:55813890 G/C cg01864836 chr14:55583639 NA -0.37 -6.55 -0.33 2.07e-10 Protein biomarker; LIHC cis rs918629 0.761 rs6881872 chr5:95286726 A/C cg10483112 chr5:95245456 ELL2 -0.37 -6.22 -0.32 1.42e-9 IgG glycosylation; LIHC cis rs11864453 0.647 rs7194397 chr16:72128299 C/T cg01557791 chr16:72042693 DHODH -0.45 -7.51 -0.38 5.08e-13 Fibrinogen levels; LIHC cis rs34779708 0.897 rs11010131 chr10:35513316 A/C cg03585969 chr10:35415529 CREM 0.86 12.65 0.56 2.29e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6570726 0.905 rs388728 chr6:145816419 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.84 0.47 2.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs651907 0.535 rs11711903 chr3:101500748 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.2 0.52 4.96e-25 Colorectal cancer; LIHC cis rs9917256 0.831 rs908594 chr2:169133796 A/G cg07857142 chr2:169103971 STK39 0.54 6.02 0.31 4.41e-9 Parkinson's disease; LIHC cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg07636037 chr3:49044803 WDR6 0.74 12.17 0.55 1.48e-28 Menarche (age at onset); LIHC cis rs3770081 1.000 rs2303339 chr2:86346180 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.83 8.38 0.41 1.36e-15 Facial emotion recognition (sad faces); LIHC cis rs6076065 0.748 rs2424542 chr20:23386800 C/T cg11657817 chr20:23433608 CST11 0.32 6.79 0.34 4.85e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.48 0.33 3.16e-10 Mean platelet volume; LIHC cis rs1434579 0.897 rs12610672 chr19:44945571 G/T cg15540054 chr19:45004280 ZNF180 -0.51 -7.19 -0.36 4.24e-12 Tuberculosis; LIHC cis rs9549367 0.789 rs2287248 chr13:113889226 T/C cg18105134 chr13:113819100 PROZ -0.67 -11.63 -0.53 1.48e-26 Platelet distribution width; LIHC cis rs7845219 0.544 rs6987400 chr8:95921295 T/C cg13393036 chr8:95962371 TP53INP1 -0.31 -5.84 -0.3 1.21e-8 Type 2 diabetes; LIHC cis rs1005277 0.579 rs1780122 chr10:38529509 C/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.54 -0.46 2.77e-19 Extrinsic epigenetic age acceleration; LIHC cis rs9513627 0.915 rs80270035 chr13:100121784 C/T cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC trans rs4650994 0.625 rs6681348 chr1:178526271 A/C cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.69 0.38 1.53e-13 Height; LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg12311636 chr6:118886798 C6orf204 0.51 5.89 0.3 9.24e-9 Diastolic blood pressure; LIHC cis rs62179067 0.708 rs11885450 chr2:179936317 G/A cg07532576 chr2:179544947 TTN 0.61 5.8 0.3 1.49e-8 Late-onset Alzheimer's disease; LIHC trans rs1814175 0.529 rs10839396 chr11:49852406 G/T cg15704280 chr7:45808275 SEPT13 0.86 13.43 0.59 2.47e-33 Height; LIHC cis rs6088813 1.000 rs6088812 chr20:33974163 T/A cg14752227 chr20:34000481 UQCC -0.41 -5.83 -0.3 1.25e-8 Height; LIHC cis rs6456156 0.586 rs2017338 chr6:167471714 G/A cg07741184 chr6:167504864 NA 0.29 6.86 0.35 3.3e-11 Primary biliary cholangitis; LIHC cis rs6061231 0.544 rs2427314 chr20:60973666 C/T cg24112000 chr20:60950667 NA -0.59 -8.79 -0.43 7.64e-17 Colorectal cancer; LIHC cis rs9649213 0.593 rs6465678 chr7:98004057 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.36 -5.73 -0.3 2.23e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg21229253 chr9:134406525 UCK1 -0.41 -6.16 -0.32 2.01e-9 Neuroblastoma; LIHC cis rs6089829 0.925 rs4809270 chr20:61676709 C/A cg08564027 chr20:61660810 NA 0.37 6.7 0.34 8.81e-11 Prostate cancer (SNP x SNP interaction); LIHC cis rs5769707 0.681 rs8140095 chr22:50043795 A/G cg01652190 chr22:50026171 C22orf34 -0.35 -7.83 -0.39 6.32e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1008375 1.000 rs10939744 chr4:17664473 G/T cg16339924 chr4:17578868 LAP3 0.43 6.16 0.32 2.1e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6840360 0.571 rs17275577 chr4:152519899 G/A cg22705602 chr4:152727874 NA -0.32 -6.19 -0.32 1.73e-9 Intelligence (multi-trait analysis); LIHC cis rs263063 0.506 rs12611002 chr19:5051655 C/T cg18473234 chr19:5097819 KDM4B 0.65 7.7 0.38 1.44e-13 Periodontitis (CDC/AAP); LIHC cis rs9326248 0.911 rs11216284 chr11:117003060 C/T cg15534755 chr11:117069859 TAGLN 0.37 6.24 0.32 1.28e-9 Blood protein levels; LIHC cis rs9296092 0.538 rs9461875 chr6:33516644 C/T cg13560919 chr6:33536144 NA -0.39 -6.33 -0.32 7.6e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7618501 0.633 rs9866695 chr3:50069452 G/T cg24110177 chr3:50126178 RBM5 0.49 7.92 0.39 3.35e-14 Intelligence (multi-trait analysis); LIHC cis rs3008870 1.000 rs3008859 chr1:67390999 G/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.45 0.66 3.47e-45 Lymphocyte percentage of white cells; LIHC cis rs9901225 1 rs9901225 chr17:40755811 C/T cg23622369 chr17:40706682 HSD17B1 -0.4 -6.61 -0.34 1.44e-10 Colorectal or endometrial cancer; LIHC cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg24531977 chr5:56204891 C5orf35 0.74 10.53 0.49 1.17e-22 Initial pursuit acceleration; LIHC cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg13770153 chr20:60521292 NA -0.36 -7.15 -0.36 5.34e-12 Body mass index; LIHC cis rs4595586 0.545 rs1607041 chr12:39368206 C/T cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs9911578 0.967 rs6503883 chr17:56917543 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -8.83 -0.43 5.37e-17 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg06420487 chr17:61919686 SMARCD2 0.44 6.02 0.31 4.5e-9 Height; LIHC cis rs4423214 1.000 rs3750997 chr11:71158841 A/C cg05163923 chr11:71159392 DHCR7 0.76 11.06 0.51 1.66e-24 Vitamin D levels; LIHC cis rs11676348 0.846 rs6723449 chr2:218997580 C/T cg00012203 chr2:219082015 ARPC2 0.54 7.67 0.38 1.86e-13 Ulcerative colitis; LIHC cis rs9326248 1.000 rs4938354 chr11:117051165 A/G cg11861562 chr11:117069780 TAGLN 0.48 7.96 0.4 2.5e-14 Blood protein levels; LIHC cis rs17818399 0.708 rs1531133 chr2:46843631 A/G cg02822958 chr2:46747628 ATP6V1E2 0.41 6.53 0.33 2.33e-10 Height; LIHC cis rs4728302 0.869 rs13233690 chr7:133587328 C/T cg10665199 chr7:133106180 EXOC4 0.36 6.3 0.32 8.9e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg02290350 chr8:58132656 NA 0.41 8.5 0.42 5.9e-16 Developmental language disorder (linguistic errors); LIHC cis rs716804 0.740 rs12279861 chr11:10263225 C/T cg01453529 chr11:10209919 SBF2 -0.29 -5.86 -0.3 1.11e-8 Neuroticism; LIHC cis rs4727027 0.866 rs3927307 chr7:148774869 C/T cg23583168 chr7:148888333 NA -0.66 -9.21 -0.45 3.36e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs17102423 0.602 rs1270073 chr14:65566257 C/A cg16583315 chr14:65563665 MAX -0.4 -8.24 -0.41 3.64e-15 Obesity-related traits; LIHC cis rs9649213 0.593 rs3801256 chr7:97992095 C/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.26e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs1862618 0.853 rs252910 chr5:56192983 G/A cg24531977 chr5:56204891 C5orf35 -0.72 -10.13 -0.48 2.83e-21 Initial pursuit acceleration; LIHC cis rs7911264 0.905 rs7918084 chr10:94429467 C/T cg25093409 chr10:94429542 NA 0.39 5.94 0.31 6.84e-9 Inflammatory bowel disease; LIHC cis rs1008375 1.000 rs2872959 chr4:17677163 G/A cg16339924 chr4:17578868 LAP3 -0.48 -6.3 -0.32 9.39e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs807029 0.533 rs12571302 chr10:102742763 C/A cg25179470 chr10:102756915 LZTS2 0.45 6.36 0.32 6.65e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs801193 0.660 rs974239 chr7:66213491 G/A cg18876405 chr7:65276391 NA 0.34 6.13 0.31 2.45e-9 Aortic root size; LIHC cis rs798554 0.616 rs1636251 chr7:2884720 T/C cg19717773 chr7:2847554 GNA12 -0.32 -5.87 -0.3 1.02e-8 Height; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg10962125 chr10:99094715 FRAT2 -0.39 -6.09 -0.31 2.98e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03045169 chr17:62503007 CCDC45;DDX5 0.41 6.61 0.34 1.48e-10 Cognitive function; LIHC cis rs4555082 0.874 rs3000075 chr14:105713219 C/T cg06808227 chr14:105710500 BRF1 0.61 8.51 0.42 5.36e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs2073300 0.609 rs6132605 chr20:23354839 A/C cg16736954 chr20:23401023 NAPB 0.7 8.15 0.4 6.87e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg03806693 chr22:41940476 POLR3H 1.12 12.8 0.57 6.57e-31 Vitiligo; LIHC cis rs611744 0.870 rs381742 chr8:109142079 G/T cg21045802 chr8:109455806 TTC35 0.49 8.36 0.41 1.56e-15 Dupuytren's disease; LIHC cis rs9811920 0.609 rs13317017 chr3:99665521 A/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.8 -0.3 1.48e-8 Axial length; LIHC cis rs7551222 0.716 rs4951078 chr1:204491802 A/G cg20240347 chr1:204465584 NA -0.36 -7.66 -0.38 1.89e-13 Schizophrenia; LIHC cis rs9322817 0.691 rs7769270 chr6:105230729 C/A cg02098413 chr6:105308735 HACE1 -0.43 -7.85 -0.39 5.55e-14 Thyroid stimulating hormone; LIHC cis rs72781680 0.611 rs2303289 chr2:24342242 C/G cg06627628 chr2:24431161 ITSN2 0.61 7.14 0.36 5.63e-12 Lymphocyte counts; LIHC cis rs2120019 0.567 rs8029351 chr15:75177237 A/C cg09165964 chr15:75287851 SCAMP5 -0.48 -6.38 -0.33 5.84e-10 Blood trace element (Zn levels); LIHC cis rs1552244 0.751 rs12715665 chr3:10021601 C/T cg00149659 chr3:10157352 C3orf10 0.49 5.85 0.3 1.12e-8 Alzheimer's disease; LIHC cis rs116095464 0.614 rs62344339 chr5:252995 T/G cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs3859192 0.577 rs2227333 chr17:38174167 C/G cg17467752 chr17:38218738 THRA -0.5 -8.6 -0.42 2.94e-16 White blood cell count; LIHC cis rs8016982 0.589 rs4640110 chr14:81692191 A/G cg01989461 chr14:81687754 GTF2A1 -0.47 -8.07 -0.4 1.22e-14 Schizophrenia; LIHC cis rs6952808 0.823 rs10950448 chr7:1966492 G/C cg21782813 chr7:2030301 MAD1L1 0.46 7.91 0.39 3.61e-14 Bipolar disorder and schizophrenia; LIHC cis rs10876993 0.928 rs2640631 chr12:58067532 A/T cg15848620 chr12:58087721 OS9 -0.58 -8.03 -0.4 1.54e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs2455799 0.574 rs2102212 chr3:15704223 C/T cg16303742 chr3:15540471 COLQ -0.39 -6.64 -0.34 1.25e-10 Mean platelet volume; LIHC cis rs1198430 0.925 rs1207124 chr1:23760408 A/G cg13183780 chr1:23809682 ASAP3 -0.5 -7.43 -0.37 8.7e-13 Total cholesterol levels; LIHC cis rs35306767 0.855 rs34251037 chr10:867884 C/T cg20503657 chr10:835505 NA 1.34 13.9 0.6 3.84e-35 Eosinophil percentage of granulocytes; LIHC cis rs7937682 1.000 rs10789843 chr11:111576158 C/T cg09085632 chr11:111637200 PPP2R1B 1.09 13.26 0.58 1.11e-32 Primary sclerosing cholangitis; LIHC cis rs9790314 1.000 rs7647327 chr3:161016421 T/C cg04691961 chr3:161091175 C3orf57 -0.39 -6.24 -0.32 1.3e-9 Morning vs. evening chronotype; LIHC cis rs6570726 0.791 rs441290 chr6:145883183 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.88 0.3 9.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg18404041 chr3:52824283 ITIH1 -0.45 -7.15 -0.36 5.45e-12 Electroencephalogram traits; LIHC cis rs7258465 0.931 rs8107347 chr19:18612748 G/A cg10790698 chr19:18539756 SSBP4 -0.35 -7.35 -0.37 1.46e-12 Breast cancer; LIHC cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg06618935 chr21:46677482 NA -0.3 -5.76 -0.3 1.86e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1555322 0.530 rs2250205 chr20:33867924 C/T cg07134254 chr20:33865797 NA 0.5 5.71 0.3 2.4e-8 Attention deficit hyperactivity disorder; LIHC cis rs950169 0.845 rs4106951 chr15:84833394 C/G cg12863693 chr15:85201151 NMB 0.4 5.8 0.3 1.47e-8 Schizophrenia; LIHC cis rs7927771 1.000 rs10838738 chr11:47663049 A/G cg20307385 chr11:47447363 PSMC3 -0.45 -5.91 -0.3 8.17e-9 Subjective well-being; LIHC cis rs8072100 0.935 rs78551919 chr17:45626002 A/C cg08085267 chr17:45401833 C17orf57 0.56 8.39 0.41 1.3e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1865760 0.929 rs2876693 chr6:25954434 C/G cg12310025 chr6:25882481 NA -0.4 -6.02 -0.31 4.44e-9 Height; LIHC cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.55 -6.53 -0.33 2.39e-10 Diastolic blood pressure; LIHC cis rs7772486 0.754 rs2328709 chr6:146106819 A/G cg23711669 chr6:146136114 FBXO30 -0.76 -14.12 -0.61 5.56e-36 Lobe attachment (rater-scored or self-reported); LIHC trans rs11039798 0.925 rs6485831 chr11:48455031 A/T cg15704280 chr7:45808275 SEPT13 0.58 6.07 0.31 3.4e-9 Axial length; LIHC cis rs8180040 0.903 rs13094438 chr3:47277885 G/A cg16586182 chr3:47516702 SCAP -0.53 -9.5 -0.46 3.72e-19 Colorectal cancer; LIHC cis rs61677309 0.638 rs7940554 chr11:118142930 C/T cg06090739 chr11:118230722 UBE4A 0.3 5.72 0.3 2.31e-8 Lung cancer in ever smokers; LIHC trans rs2727020 0.615 rs10128582 chr11:49447424 C/T cg15704280 chr7:45808275 SEPT13 -0.93 -19.33 -0.72 8.85e-57 Coronary artery disease; LIHC cis rs1003719 0.788 rs4817844 chr21:38447064 A/T cg10648535 chr21:38446584 PIGP;TTC3 -0.77 -12.18 -0.55 1.38e-28 Eye color traits; LIHC cis rs9457247 0.967 rs402191 chr6:167405553 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs6952407 1 rs6952407 chr7:66045512 A/G cg00343986 chr7:65444356 GUSB -0.41 -5.75 -0.3 1.93e-8 Cotinine glucuronidation; LIHC cis rs10193935 0.792 rs7559001 chr2:42474301 C/T cg27598129 chr2:42591480 NA -0.69 -10.23 -0.48 1.34e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs4919694 1.000 rs7100592 chr10:104769098 T/G cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs12200782 1.000 rs72845509 chr6:26639865 T/C cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs400736 0.740 rs225129 chr1:8094164 T/A cg25007680 chr1:8021821 PARK7 0.63 9.92 0.47 1.46e-20 Response to antidepressants and depression; LIHC cis rs16828019 0.852 rs12045171 chr1:41528805 G/A cg03387723 chr1:41708464 SCMH1 -0.4 -6.82 -0.35 4.05e-11 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.781 rs7742161 chr6:127571676 T/C cg24812749 chr6:127587940 RNF146 0.66 9.77 0.47 4.81e-20 Breast cancer; LIHC cis rs16866061 1.000 rs72974267 chr2:225454209 T/C cg12698349 chr2:225449008 CUL3 0.79 13.9 0.6 4.01e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg00280220 chr17:61926910 NA 0.44 7.15 0.36 5.34e-12 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs11718455 0.960 rs34179760 chr3:44002303 A/G cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs11098699 1.000 rs11940736 chr4:124171702 A/G cg09941581 chr4:124220074 SPATA5 0.35 6.52 0.33 2.57e-10 Mosquito bite size; LIHC cis rs225245 0.817 rs1634684 chr17:33941051 A/G cg05299278 chr17:33885742 SLFN14 0.22 5.84 0.3 1.19e-8 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs7312933 1.000 rs7957213 chr12:42475438 T/G cg01256987 chr12:42539512 GXYLT1 -0.41 -6.86 -0.35 3.29e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg20295408 chr7:1910781 MAD1L1 -0.41 -6.06 -0.31 3.58e-9 Bipolar disorder and schizophrenia; LIHC cis rs6952808 0.771 rs10950415 chr7:1914477 A/G cg20295408 chr7:1910781 MAD1L1 -0.51 -7.4 -0.37 1.07e-12 Bipolar disorder and schizophrenia; LIHC cis rs3767633 0.925 rs2499856 chr1:161926637 C/T cg09175582 chr1:161736000 ATF6 -0.55 -6.01 -0.31 4.74e-9 IgG glycosylation; LIHC cis rs4808199 0.895 rs10403731 chr19:19469296 G/A cg03709012 chr19:19516395 GATAD2A 1.0 16.13 0.66 6.25e-44 Nonalcoholic fatty liver disease; LIHC cis rs4820318 1 rs4820318 chr22:38570313 G/A cg25457927 chr22:38595422 NA -0.35 -8.61 -0.42 2.7e-16 Breast cancer; LIHC cis rs7106204 0.514 rs11027789 chr11:24260906 T/C ch.11.24196551F chr11:24239977 NA 0.75 9.4 0.45 7.88e-19 Response to Homoharringtonine (cytotoxicity); LIHC cis rs11711311 1.000 rs12632983 chr3:113481913 A/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.3 0.41 2.45e-15 IgG glycosylation; LIHC cis rs644799 1.000 rs557079 chr11:95530125 C/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.52e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs929354 0.742 rs7807556 chr7:156934329 T/C cg05182265 chr7:156933206 UBE3C -0.33 -6.1 -0.31 2.9e-9 Body mass index; LIHC cis rs7772486 0.686 rs857879 chr6:145974043 C/A cg23711669 chr6:146136114 FBXO30 -0.61 -11.11 -0.51 1.12e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs3806843 0.966 rs2563260 chr5:140137867 C/A cg19875535 chr5:140030758 IK -0.37 -6.1 -0.31 2.86e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg04287289 chr16:89883240 FANCA -0.52 -8.42 -0.41 1.03e-15 Vitiligo; LIHC cis rs12971120 0.783 rs7229256 chr18:72169129 T/A cg26446133 chr18:72167187 CNDP2 -0.79 -15.9 -0.65 5.27e-43 Refractive error; LIHC cis rs9399137 0.507 rs11759062 chr6:135381248 A/C cg24558204 chr6:135376177 HBS1L 0.64 10.67 0.5 4.01e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg19635926 chr16:89946313 TCF25 0.54 7.33 0.37 1.68e-12 Skin colour saturation; LIHC cis rs8180040 0.764 rs11712716 chr3:47193432 T/C cg16586182 chr3:47516702 SCAP -0.5 -8.93 -0.43 2.66e-17 Colorectal cancer; LIHC cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.95 0.35 1.89e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7635838 0.684 rs2594966 chr3:11325276 A/G cg00170343 chr3:11313890 ATG7 -0.6 -10.24 -0.48 1.19e-21 HDL cholesterol; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg08280861 chr8:58055591 NA 0.51 6.13 0.31 2.46e-9 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16456337 chr5:112312164 DCP2 0.4 6.09 0.31 3.01e-9 Lung function (FEV1/FVC); LIHC cis rs7216064 1.000 rs1976054 chr17:65833224 T/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.73 -0.47 6.67e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs8017423 0.934 rs2401874 chr14:90682467 C/T cg14092571 chr14:90743983 NA -0.36 -5.76 -0.3 1.83e-8 Mortality in heart failure; LIHC cis rs4820539 0.966 rs5751587 chr22:23470090 G/A cg14186256 chr22:23484241 RTDR1 0.98 21.52 0.76 1.48e-65 Bone mineral density; LIHC cis rs17854409 1.000 rs16983290 chr20:61478894 A/G cg05147244 chr20:61493195 TCFL5 -1.16 -11.12 -0.52 1.01e-24 Obesity-related traits; LIHC cis rs4243830 1.000 rs10158949 chr1:6583701 T/C cg22792644 chr1:6614718 TAS1R1;NOL9 -0.81 -7.64 -0.38 2.14e-13 Body mass index; LIHC cis rs796364 0.715 rs1106399 chr2:201003837 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.66 -7.66 -0.38 1.96e-13 Schizophrenia; LIHC cis rs963731 0.579 rs6544195 chr2:39288486 A/G cg04010122 chr2:39346883 SOS1 -0.66 -5.94 -0.31 6.92e-9 Corticobasal degeneration; LIHC cis rs2228479 0.850 rs17232910 chr16:89839766 G/C cg19635926 chr16:89946313 TCF25 0.5 6.47 0.33 3.38e-10 Skin colour saturation; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.14 0.55 1.93e-28 Prudent dietary pattern; LIHC cis rs16866061 0.962 rs3845840 chr2:225359100 G/A cg12698349 chr2:225449008 CUL3 0.76 13.21 0.58 1.83e-32 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs7618501 1.000 rs3811696 chr3:49761605 C/T cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC cis rs1551570 0.755 rs7401 chr19:10225777 A/G cg16327482 chr19:10226339 EIF3G 0.49 8.42 0.41 1.06e-15 Narcolepsy; LIHC cis rs7937890 0.904 rs11023169 chr11:14290985 C/A cg23387056 chr11:14280742 SPON1 0.44 6.13 0.31 2.37e-9 Mitochondrial DNA levels; LIHC cis rs748404 0.631 rs28702649 chr15:43648629 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.54 8.49 0.42 6.44e-16 Lung cancer; LIHC cis rs722599 0.748 rs741096 chr14:75351487 A/G cg11812906 chr14:75593930 NEK9 -0.45 -7.22 -0.36 3.36e-12 IgG glycosylation; LIHC cis rs17270561 0.779 rs12209218 chr6:25887776 C/A cg16482183 chr6:26056742 HIST1H1C 0.65 7.92 0.39 3.4e-14 Iron status biomarkers; LIHC cis rs3768617 0.528 rs10737242 chr1:183098249 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.58 0.5 8.23e-23 Fuchs's corneal dystrophy; LIHC cis rs9303401 0.614 rs2007993 chr17:56590643 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.95 12.84 0.57 4.49e-31 Cognitive test performance; LIHC cis rs7208859 0.673 rs2269916 chr17:29233763 A/G cg13385521 chr17:29058706 SUZ12P 0.84 8.15 0.4 7.08e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1559088 0.948 rs10406916 chr19:33590093 G/A cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1801251 1.000 rs2592105 chr2:233645968 C/G cg25237894 chr2:233734115 C2orf82 0.59 11.28 0.52 2.66e-25 Coronary artery disease; LIHC cis rs67311347 1.000 rs34762643 chr3:40475433 C/T cg13409248 chr3:40428643 ENTPD3 0.41 6.9 0.35 2.58e-11 Renal cell carcinoma; LIHC cis rs12618769 0.652 rs1516085 chr2:99232312 G/A cg10123293 chr2:99228465 UNC50 0.37 5.78 0.3 1.68e-8 Bipolar disorder; LIHC cis rs875971 0.825 rs1860472 chr7:66082723 T/C cg18252515 chr7:66147081 NA 0.45 6.56 0.33 1.97e-10 Aortic root size; LIHC cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.51e-29 Menopause (age at onset); LIHC cis rs79149102 0.579 rs76900720 chr15:75348895 A/T cg17294928 chr15:75287854 SCAMP5 -0.51 -6.36 -0.33 6.43e-10 Lung cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23524709 chr19:4636345 NA 0.53 6.91 0.35 2.32e-11 Lung function (FEV1/FVC); LIHC cis rs1552244 0.816 rs56387520 chr3:10042782 C/T cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs1055129 0.537 rs1135640 chr17:73949540 C/G cg19302996 chr17:73780495 UNK 0.48 6.75 0.34 6.31e-11 White matter hyperintensity burden; LIHC cis rs8141529 0.732 rs5762784 chr22:29171298 C/T cg15103426 chr22:29168792 CCDC117 0.69 11.8 0.54 3.53e-27 Lymphocyte counts; LIHC cis rs644799 1.000 rs586238 chr11:95560371 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4575098 0.681 rs11591206 chr1:161111363 C/T cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.4 7.29 0.37 2.13e-12 Monocyte percentage of white cells; LIHC cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg15691649 chr6:25882328 NA -0.97 -15.09 -0.63 8.46e-40 Urate levels; LIHC cis rs11779988 0.545 rs415840 chr8:17782134 C/T cg01800426 chr8:17659068 MTUS1 -0.42 -5.96 -0.31 6.2e-9 Breast cancer; LIHC cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg23149560 chr2:74406255 MOBKL1B -0.43 -6.18 -0.32 1.82e-9 Gestational age at birth (maternal effect); LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 7.98 0.4 2.17e-14 Height; LIHC cis rs16828019 0.929 rs1032728 chr1:41679566 A/T cg03387723 chr1:41708464 SCMH1 -0.44 -7.18 -0.36 4.42e-12 Intelligence (multi-trait analysis); LIHC cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg25811766 chr13:21894605 NA 0.77 13.3 0.58 7.81e-33 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs797680 0.856 rs12030549 chr1:93669218 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.33 -5.84 -0.3 1.23e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs4803468 1.000 rs17318666 chr19:41940342 T/G cg09537434 chr19:41945824 ATP5SL 1.02 21.13 0.75 5.31e-64 Height; LIHC cis rs9303401 0.659 rs17741087 chr17:56550300 C/T cg25039879 chr17:56429692 SUPT4H1 0.75 8.41 0.41 1.1e-15 Cognitive test performance; LIHC trans rs7618501 1.000 rs35261599 chr3:49773236 G/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs4668356 0.543 rs1989613 chr2:172034292 A/G cg13882835 chr2:172017928 TLK1 -0.45 -6.03 -0.31 4.2e-9 Cognitive performance; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20623868 chr19:15666885 NA 0.42 6.17 0.32 1.91e-9 Lung function (FEV1/FVC); LIHC cis rs10870270 0.956 rs7894 chr10:133769482 G/C cg17892150 chr10:133769511 PPP2R2D -0.68 -12.85 -0.57 3.99e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2075371 0.932 rs2598290 chr7:133987736 C/G cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC cis rs6500602 0.727 rs11644481 chr16:4581002 T/G cg08645402 chr16:4508243 NA 0.43 8.03 0.4 1.6e-14 Schizophrenia; LIHC cis rs898097 0.690 rs3785520 chr17:80895745 T/C cg15664640 chr17:80829946 TBCD 0.64 10.03 0.48 6.52e-21 Breast cancer; LIHC cis rs9500256 0.967 rs1012500 chr6:58304669 G/A cg03371099 chr6:57305889 PRIM2 -0.4 -7.09 -0.36 7.65e-12 Eosinophilic esophagitis (pediatric); LIHC cis rs56235845 0.694 rs11748912 chr5:176765395 G/A cg06060754 chr5:176797920 RGS14 0.47 6.67 0.34 1.02e-10 Hemoglobin concentration;Hematocrit; LIHC cis rs801193 0.935 rs3800820 chr7:66147178 C/T cg11764359 chr7:65958608 NA -0.71 -10.72 -0.5 2.53e-23 Aortic root size; LIHC trans rs11098499 0.730 rs12505735 chr4:120532956 G/T cg25214090 chr10:38739885 LOC399744 0.58 9.45 0.46 5.71e-19 Corneal astigmatism; LIHC cis rs2717559 0.542 rs11777634 chr8:143887957 C/T cg06565975 chr8:143823917 SLURP1 -0.4 -6.68 -0.34 9.6e-11 Urinary tract infection frequency; LIHC cis rs6500602 0.702 rs4786511 chr16:4571645 C/T cg08645402 chr16:4508243 NA 0.44 8.34 0.41 1.82e-15 Schizophrenia; LIHC cis rs508618 0.666 rs480902 chr1:231531627 C/T cg06096015 chr1:231504339 EGLN1 -0.39 -7.08 -0.36 8.42e-12 Red blood cell count; LIHC cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg19318889 chr4:1322082 MAEA 0.43 5.95 0.31 6.65e-9 Obesity-related traits; LIHC cis rs13161895 1.000 rs394616 chr5:179418134 T/G cg06664874 chr5:179499304 RNF130 0.57 7.03 0.36 1.16e-11 LDL cholesterol; LIHC trans rs1814175 0.646 rs10839335 chr11:49715265 G/T cg15704280 chr7:45808275 SEPT13 -0.97 -20.66 -0.75 4.12e-62 Height; LIHC cis rs11888559 0.655 rs6435172 chr2:203953234 G/C cg24605529 chr2:203879461 NBEAL1 0.75 5.78 0.3 1.66e-8 Height; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.05 0.55 4.17e-28 Prudent dietary pattern; LIHC cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg04944784 chr2:26401820 FAM59B -0.73 -9.22 -0.45 3.12e-18 Gut microbiome composition (summer); LIHC cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg12373951 chr3:133503437 NA 0.75 13.78 0.6 1.12e-34 Iron status biomarkers; LIHC cis rs778371 0.676 rs2293780 chr2:233635213 T/C cg08000102 chr2:233561755 GIGYF2 0.89 14.94 0.63 3.3e-39 Schizophrenia; LIHC cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs72843506 0.656 rs73984573 chr17:19985340 A/G cg12065943 chr17:19881925 AKAP10 -0.33 -5.76 -0.3 1.9e-8 Schizophrenia; LIHC cis rs7582720 1.000 rs72934740 chr2:203741362 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7188697 0.922 rs37051 chr16:58558102 C/T cg02549819 chr16:58548995 SETD6 -0.45 -7.11 -0.36 6.73e-12 QT interval; LIHC cis rs4808199 0.948 rs11085261 chr19:19462606 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.57 8.24 0.41 3.74e-15 Nonalcoholic fatty liver disease; LIHC cis rs9914988 0.673 rs9890212 chr17:27169890 G/C cg20469991 chr17:27169893 C17orf63 -0.62 -7.16 -0.36 5.07e-12 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs12477438 0.953 rs3851334 chr2:99794704 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.06 -10.82 -0.51 1.12e-23 Chronic sinus infection; LIHC cis rs9393777 0.557 rs9358949 chr6:26485717 A/C cg12826209 chr6:26865740 GUSBL1 0.59 5.83 0.3 1.28e-8 Intelligence (multi-trait analysis); LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg21157115 chr9:33001303 APTX -0.57 -6.33 -0.32 7.53e-10 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs2075371 1.000 rs2241335 chr7:133979368 C/T cg11752832 chr7:134001865 SLC35B4 0.51 7.65 0.38 2.13e-13 Mean platelet volume; LIHC cis rs9914988 0.943 rs11656256 chr17:27153553 G/A cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6545883 0.894 rs4672431 chr2:61519922 C/A cg15711740 chr2:61764176 XPO1 0.42 5.78 0.3 1.69e-8 Tuberculosis; LIHC trans rs75804782 0.641 rs72983853 chr2:239324210 C/T cg01134436 chr17:81009848 B3GNTL1 0.73 6.11 0.31 2.67e-9 Morning vs. evening chronotype;Chronotype; LIHC cis rs950169 0.887 rs35986397 chr15:84955107 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 8.64 0.42 2.12e-16 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15779458 chr2:233415951 TIGD1;EIF4E2 0.46 6.6 0.34 1.52e-10 Cognitive function; LIHC cis rs6952808 0.594 rs3778964 chr7:2138109 C/T cg02951883 chr7:2050386 MAD1L1 -0.65 -10.65 -0.5 4.68e-23 Bipolar disorder and schizophrenia; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg27539721 chr12:102133366 SYCP3 -0.47 -6.43 -0.33 4.33e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg18252515 chr7:66147081 NA -1.31 -17.08 -0.68 1.01e-47 Diabetic kidney disease; LIHC cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.99 8.93 0.43 2.62e-17 Platelet count; LIHC cis rs4820294 0.669 rs7287358 chr22:38054403 A/G cg00142150 chr22:38071001 LGALS1 0.44 7.48 0.38 6.14e-13 Fat distribution (HIV); LIHC cis rs9309711 0.961 rs11890651 chr2:3482796 T/G cg10845886 chr2:3471009 TTC15 -0.57 -10.85 -0.51 9.37e-24 Neurofibrillary tangles; LIHC cis rs611744 0.967 rs584716 chr8:109178634 A/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs7089973 0.668 rs7077148 chr10:116644896 A/G cg03647239 chr10:116582469 FAM160B1 0.45 6.5 0.33 2.78e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2073300 0.609 rs1936011 chr20:23341912 G/C cg12062639 chr20:23401060 NAPB 1.06 14.13 0.61 5.04e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03705947 chr1:68152081 GADD45A 0.42 6.7 0.34 8.5e-11 Pancreatic cancer; LIHC cis rs5769765 1.000 rs5770742 chr22:50270309 T/C cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs6500602 0.929 rs9926114 chr16:4478322 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 6.07 0.31 3.46e-9 Schizophrenia; LIHC cis rs8014671 0.553 rs11628785 chr14:70908217 G/A cg25576086 chr14:70833871 SYNJ2BP -0.46 -7.15 -0.36 5.34e-12 Prostate cancer; LIHC cis rs9787249 0.957 rs1046988 chr1:40219065 A/G cg02773041 chr1:40204384 PPIE -0.41 -5.87 -0.3 1.03e-8 Blood protein levels; LIHC trans rs1814175 0.791 rs10769593 chr11:49616217 T/C cg03929089 chr4:120376271 NA -0.89 -17.97 -0.7 2.53e-51 Height; LIHC trans rs11098499 0.908 rs11098527 chr4:120399906 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.73 0.47 6.3e-20 Corneal astigmatism; LIHC cis rs17152411 1.000 rs10901837 chr10:126614618 G/A cg07906193 chr10:126599966 NA 0.47 7.36 0.37 1.34e-12 Height; LIHC trans rs4714291 0.862 rs2984445 chr6:40069935 C/T cg02267698 chr19:7991119 CTXN1 -0.4 -6.78 -0.34 5.43e-11 Strep throat; LIHC cis rs853679 0.517 rs9468297 chr6:28118874 G/T cg16479474 chr6:28041457 NA 0.46 6.44 0.33 4.04e-10 Depression; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg02592271 chr2:27665507 KRTCAP3 -0.47 -6.41 -0.33 4.92e-10 Total body bone mineral density; LIHC cis rs9486715 0.867 rs1855533 chr6:97050265 T/C cg06623918 chr6:96969491 KIAA0776 -0.86 -15.49 -0.64 2.2e-41 Headache; LIHC cis rs912057 0.671 rs1294420 chr6:6742752 C/T cg06612196 chr6:6737390 NA 0.51 9.68 0.46 9.91e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg06481639 chr22:41940642 POLR3H -0.73 -7.29 -0.37 2.18e-12 Vitiligo; LIHC cis rs35110281 0.720 rs162375 chr21:44927015 C/T cg01579765 chr21:45077557 HSF2BP 0.33 6.15 0.32 2.16e-9 Mean corpuscular volume; LIHC cis rs9911578 0.967 rs2429369 chr17:56501420 A/G cg12560992 chr17:57184187 TRIM37 0.93 16.4 0.66 5.29e-45 Intelligence (multi-trait analysis); LIHC cis rs12701220 0.817 rs59471534 chr7:1085224 G/A cg04025307 chr7:1156635 C7orf50 0.46 6.19 0.32 1.71e-9 Bronchopulmonary dysplasia; LIHC cis rs965469 1.000 rs6037538 chr20:3282978 T/C cg25506879 chr20:3388711 C20orf194 -0.56 -6.71 -0.34 7.86e-11 IFN-related cytopenia; LIHC cis rs72781680 0.716 rs6718631 chr2:24036086 A/G cg08917208 chr2:24149416 ATAD2B -0.59 -5.97 -0.31 5.8e-9 Lymphocyte counts; LIHC cis rs66887589 0.777 rs1814815 chr4:120258091 C/T cg09307838 chr4:120376055 NA 0.45 6.91 0.35 2.39e-11 Diastolic blood pressure; LIHC cis rs17270561 0.636 rs1165157 chr6:25792250 A/G cg17691542 chr6:26056736 HIST1H1C 0.44 6.01 0.31 4.75e-9 Iron status biomarkers; LIHC cis rs4906332 0.754 rs34235720 chr14:104004968 C/T cg19000871 chr14:103996768 TRMT61A -0.57 -9.06 -0.44 1.02e-17 Coronary artery disease; LIHC cis rs7592578 0.679 rs59929070 chr2:191327852 A/G cg10560079 chr2:191398806 TMEM194B -0.78 -11.18 -0.52 6.26e-25 Diastolic blood pressure; LIHC cis rs17685 0.753 rs3757593 chr7:75678735 G/A cg01364799 chr7:75623366 TMEM120A 0.52 7.83 0.39 6.35e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8027181 0.839 rs7176235 chr15:72999104 A/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.5 7.65 0.38 2.03e-13 Triglyceride levels; LIHC cis rs7020830 0.898 rs7846747 chr9:37167539 A/C cg14294708 chr9:37120828 ZCCHC7 1.17 27.25 0.83 1.06e-87 Schizophrenia; LIHC cis rs7772486 0.790 rs7753833 chr6:146161432 C/A cg23711669 chr6:146136114 FBXO30 0.63 11.3 0.52 2.2e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg10802521 chr3:52805072 NEK4 -0.41 -6.79 -0.34 5.1e-11 Electroencephalogram traits; LIHC cis rs10751667 0.666 rs10902235 chr11:938892 T/C cg06064525 chr11:970664 AP2A2 -0.55 -14.97 -0.63 2.48e-39 Alzheimer's disease (late onset); LIHC cis rs7937890 0.967 rs963212 chr11:14324732 A/G cg02886208 chr11:14281011 SPON1 0.58 8.52 0.42 5.24e-16 Mitochondrial DNA levels; LIHC cis rs11888559 0.655 rs4675316 chr2:204019331 T/C cg24605529 chr2:203879461 NBEAL1 0.77 5.85 0.3 1.16e-8 Height; LIHC cis rs2404602 0.692 rs12910382 chr15:77053442 A/C cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.7e-9 Blood metabolite levels; LIHC cis rs3809863 0.646 rs9899121 chr17:45395144 C/T cg25173405 chr17:45401733 C17orf57 -0.58 -8.53 -0.42 4.7e-16 Glaucoma (primary open-angle); LIHC cis rs7945705 0.935 rs2653593 chr11:8877317 G/A cg12365402 chr11:9010492 NRIP3 -0.23 -5.88 -0.3 9.54e-9 Hemoglobin concentration; LIHC cis rs3540 0.574 rs2256388 chr15:90969335 A/C cg22089800 chr15:90895588 ZNF774 -0.55 -7.57 -0.38 3.47e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs4561483 0.549 rs154149 chr16:11956118 T/A cg08843971 chr16:11963173 GSPT1 -0.39 -7.52 -0.38 4.91e-13 Testicular germ cell tumor; LIHC cis rs6951245 0.554 rs4724294 chr7:1139695 G/A cg04025307 chr7:1156635 C7orf50 0.64 6.34 0.32 7.25e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4423214 1.000 rs12792306 chr11:71166992 T/C cg24826892 chr11:71159390 DHCR7 0.47 6.12 0.31 2.52e-9 Vitamin D levels; LIHC cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg12310025 chr6:25882481 NA -0.7 -8.71 -0.43 1.31e-16 Intelligence (multi-trait analysis); LIHC cis rs2242116 0.796 rs2290546 chr3:46965197 C/G cg16586182 chr3:47516702 SCAP -0.4 -6.7 -0.34 8.61e-11 Birth weight; LIHC cis rs797680 0.856 rs682514 chr1:93719430 A/C cg15093775 chr1:93646470 TMED5;CCDC18 0.34 5.96 0.31 6.39e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs11148252 0.583 rs9536048 chr13:52958788 T/C cg00495681 chr13:53174319 NA 0.38 5.77 0.3 1.75e-8 Lewy body disease; LIHC cis rs1048238 0.506 rs10737911 chr1:16167855 C/T cg00529422 chr1:16285251 ZBTB17 0.35 6.72 0.34 7.46e-11 Systolic blood pressure; LIHC cis rs6586163 1.000 rs6586165 chr10:90755056 T/A cg03111039 chr10:90751583 FAS;ACTA2 -0.57 -8.36 -0.41 1.64e-15 Chronic lymphocytic leukemia; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.96 9.12 0.44 6.46e-18 Platelet count; LIHC cis rs75908454 1.000 rs78088663 chr6:169844298 C/T cg19338460 chr6:170058176 WDR27 -0.84 -7.39 -0.37 1.15e-12 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.84 0.63 8.42e-39 Prudent dietary pattern; LIHC cis rs6502050 0.871 rs6502054 chr17:80066715 G/A cg11859384 chr17:80120422 CCDC57 0.44 5.97 0.31 5.92e-9 Life satisfaction; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs11690935 0.632 rs17581284 chr2:172659376 C/T cg13550731 chr2:172543902 DYNC1I2 0.61 11.12 0.52 9.99e-25 Schizophrenia; LIHC cis rs2439831 0.850 rs3825783 chr15:44102309 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.55 6.71 0.34 7.94e-11 Lung cancer in ever smokers; LIHC cis rs1728785 1.000 rs1728789 chr16:68595776 C/T cg02972257 chr16:68554789 NA -0.55 -6.21 -0.32 1.55e-9 Ulcerative colitis; LIHC cis rs4665809 1.000 rs4233710 chr2:26291565 G/A cg27170947 chr2:26402098 FAM59B -0.69 -8.57 -0.42 3.65e-16 Gut microbiome composition (summer); LIHC cis rs796364 1.000 rs769950 chr2:200730028 A/G cg23649088 chr2:200775458 C2orf69 0.49 5.85 0.3 1.18e-8 Schizophrenia; LIHC cis rs6748734 1.000 rs4675863 chr2:241830763 A/T cg04034577 chr2:241836375 C2orf54 -0.4 -8.11 -0.4 9.08e-15 Urinary metabolites; LIHC cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg14004847 chr7:1930337 MAD1L1 -0.47 -6.72 -0.34 7.74e-11 Bipolar disorder and schizophrenia; LIHC cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 8.86 0.43 4.51e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs7044106 0.791 rs10739572 chr9:123489815 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.57 8.57 0.42 3.5e-16 Hip circumference adjusted for BMI; LIHC cis rs4919694 0.572 rs12255989 chr10:104867206 C/T cg04362960 chr10:104952993 NT5C2 0.81 7.14 0.36 5.64e-12 Arsenic metabolism; LIHC cis rs9733 0.650 rs4970923 chr1:150608300 A/G cg18016565 chr1:150552671 MCL1 -0.56 -11.21 -0.52 4.68e-25 Tonsillectomy; LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg26354017 chr1:205819088 PM20D1 0.75 11.07 0.51 1.51e-24 Menarche (age at onset); LIHC cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg21724239 chr8:58056113 NA 0.44 5.87 0.3 1.02e-8 Developmental language disorder (linguistic errors); LIHC cis rs7188697 0.922 rs2243463 chr16:58571189 T/C cg02549819 chr16:58548995 SETD6 -0.45 -7.18 -0.36 4.43e-12 QT interval; LIHC cis rs225245 0.791 rs2285742 chr17:34018682 C/T cg05299278 chr17:33885742 SLFN14 0.24 6.4 0.33 5.17e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs4906332 1.000 rs12885762 chr14:103882200 C/A cg19000871 chr14:103996768 TRMT61A -0.45 -7.71 -0.38 1.41e-13 Coronary artery disease; LIHC cis rs1190552 0.846 rs3742437 chr14:102965047 G/A cg10241871 chr14:102965420 TECPR2 -0.48 -7.59 -0.38 3.13e-13 Blood protein levels; LIHC cis rs9733 0.596 rs6669369 chr1:150695892 C/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs9309473 0.950 rs7566364 chr2:73842889 T/C cg20560298 chr2:73613845 ALMS1 -0.54 -6.73 -0.34 6.95e-11 Metabolite levels; LIHC cis rs7568458 0.684 rs7608074 chr2:85809703 T/G cg02493740 chr2:85810744 VAMP5 -0.47 -7.82 -0.39 6.57e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs6952808 1.000 rs4721121 chr7:1892565 A/G cg21782813 chr7:2030301 MAD1L1 0.41 6.86 0.35 3.14e-11 Bipolar disorder and schizophrenia; LIHC cis rs2072499 0.833 rs2251847 chr1:156204047 G/A cg25208724 chr1:156163844 SLC25A44 0.59 10.09 0.48 4.07e-21 Testicular germ cell tumor; LIHC trans rs11098499 0.775 rs10029303 chr4:120286755 T/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs6964587 1.000 rs926192 chr7:91671853 C/A cg17063962 chr7:91808500 NA 1.03 20.93 0.75 3.47e-63 Breast cancer; LIHC cis rs1048238 0.506 rs848194 chr1:16285342 G/A cg00529422 chr1:16285251 ZBTB17 0.34 6.41 0.33 4.83e-10 Systolic blood pressure; LIHC cis rs7833986 0.501 rs2976038 chr8:57028864 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.56 0.42 3.99e-16 Height; LIHC cis rs7617480 0.648 rs4858800 chr3:48755820 A/G cg07636037 chr3:49044803 WDR6 0.72 8.3 0.41 2.5e-15 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs7613875 0.600 rs2624832 chr3:50030858 C/T cg24110177 chr3:50126178 RBM5 -0.53 -8.65 -0.42 2.02e-16 Body mass index; LIHC cis rs6570726 0.599 rs426371 chr6:145886469 A/G cg13319975 chr6:146136371 FBXO30 0.52 8.31 0.41 2.22e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs6089829 0.925 rs6122087 chr20:61664553 T/C cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg10755058 chr3:40428713 ENTPD3 0.4 6.69 0.34 8.89e-11 Renal cell carcinoma; LIHC cis rs5769707 0.681 rs8140095 chr22:50043795 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.33 -0.41 1.93e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs10089 0.953 rs4836358 chr5:127376869 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.16e-11 Ileal carcinoids; LIHC cis rs4243830 0.579 rs10779794 chr1:6612651 C/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.82 -10.53 -0.49 1.21e-22 Body mass index; LIHC cis rs1789 0.786 rs6449161 chr4:15692954 A/G cg24225360 chr4:15471699 CC2D2A -0.39 -5.95 -0.31 6.5e-9 Blood protein levels; LIHC cis rs9399135 0.967 rs6910530 chr6:135332770 C/T cg24558204 chr6:135376177 HBS1L 0.42 6.87 0.35 3.12e-11 Red blood cell count; LIHC cis rs35306767 0.953 rs12762973 chr10:960761 C/G cg26597838 chr10:835615 NA 0.99 11.35 0.52 1.46e-25 Eosinophil percentage of granulocytes; LIHC cis rs2637266 1.000 rs17384253 chr10:78342391 A/G cg18941641 chr10:78392320 NA 0.28 6.03 0.31 4.19e-9 Pulmonary function; LIHC cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg23758822 chr17:41437982 NA 0.94 17.82 0.69 1.05e-50 Menopause (age at onset); LIHC cis rs826838 0.586 rs1843903 chr12:38627524 C/T cg26384229 chr12:38710491 ALG10B 0.4 6.17 0.32 1.92e-9 Heart rate; LIHC cis rs7223966 1.000 rs8069687 chr17:61883023 C/T cg05941027 chr17:61774174 LIMD2 -0.34 -7.12 -0.36 6.23e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs80282103 0.717 rs41299206 chr10:1120236 T/C cg08668510 chr10:1095578 IDI1 0.66 6.47 0.33 3.44e-10 Glomerular filtration rate (creatinine); LIHC trans rs4596713 0.507 rs10115283 chr9:71801162 T/G cg16512924 chr15:28394682 HERC2 0.38 6.17 0.32 1.94e-9 Headache; LIHC cis rs11212737 0.818 rs2624135 chr11:108513693 T/G cg22776369 chr11:108536276 DDX10 0.37 6.19 0.32 1.69e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4975616 0.843 rs4975615 chr5:1315343 C/T cg06550200 chr5:1325588 CLPTM1L 0.48 7.74 0.39 1.17e-13 Lung cancer; LIHC cis rs782590 0.522 rs12329050 chr2:55894428 G/A cg03859395 chr2:55845619 SMEK2 -0.5 -8.21 -0.41 4.57e-15 Metabolic syndrome; LIHC cis rs7106204 0.748 rs7947388 chr11:24224903 A/G ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.04e-27 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4746818 1.000 rs7476357 chr10:70935660 G/A cg11621586 chr10:70884670 VPS26A 0.87 14.32 0.61 8.96e-37 Left atrial antero-posterior diameter; LIHC cis rs6754311 0.773 rs666407 chr2:136640233 A/G cg07169764 chr2:136633963 MCM6 0.67 9.94 0.47 1.32e-20 Mosquito bite size; LIHC cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg08888203 chr3:10149979 C3orf24 0.57 6.49 0.33 3.06e-10 Alzheimer's disease; LIHC cis rs9911578 0.935 rs9893351 chr17:57023326 G/A cg05425664 chr17:57184151 TRIM37 -0.55 -8.3 -0.41 2.45e-15 Intelligence (multi-trait analysis); LIHC cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg11764359 chr7:65958608 NA -0.69 -9.29 -0.45 1.84e-18 Calcium levels; LIHC cis rs7552404 1.000 rs7548962 chr1:76139266 G/A cg22875332 chr1:76189707 ACADM 0.48 7.21 0.36 3.61e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2257205 0.667 rs7209498 chr17:56680642 G/A cg05425664 chr17:57184151 TRIM37 -0.61 -6.69 -0.34 8.94e-11 Pancreatic cancer; LIHC cis rs7208859 0.524 rs11653098 chr17:29122501 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7223966 1.000 rs15637 chr17:61772050 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.83e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs79387448 0.701 rs11465584 chr2:102982629 G/A cg09003973 chr2:102972529 NA 1.17 9.75 0.47 5.68e-20 Gut microbiota (bacterial taxa); LIHC trans rs12752401 0.717 rs12751268 chr1:103002533 C/T cg17681729 chr19:740608 PALM 0.45 6.35 0.32 6.67e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg22105103 chr4:187893119 NA -0.34 -8.46 -0.42 7.92e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs941873 0.868 rs2233718 chr10:81108956 A/G cg11057378 chr10:81107060 PPIF 0.36 5.93 0.31 7.51e-9 Height; LIHC cis rs644799 1.000 rs546809 chr11:95579938 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 16.86 0.67 7.3e-47 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9457247 0.967 rs443570 chr6:167389925 G/A cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg24549020 chr5:56110836 MAP3K1 0.48 6.15 0.32 2.17e-9 Initial pursuit acceleration; LIHC cis rs67311347 1.000 rs9848083 chr3:40466979 A/G cg13409248 chr3:40428643 ENTPD3 -0.43 -7.27 -0.37 2.47e-12 Renal cell carcinoma; LIHC cis rs910316 0.712 rs175074 chr14:75504454 G/A cg11812906 chr14:75593930 NEK9 -0.73 -13.69 -0.59 2.61e-34 Height; LIHC cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg21724239 chr8:58056113 NA 0.62 7.9 0.39 3.77e-14 Developmental language disorder (linguistic errors); LIHC cis rs17152411 1.000 rs11245440 chr10:126634572 C/T cg07906193 chr10:126599966 NA 0.47 7.05 0.36 9.93e-12 Height; LIHC cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg21294424 chr19:58662284 ZNF329 0.92 7.09 0.36 7.8e-12 Cholesterol, total; LIHC cis rs7534824 0.625 rs17449022 chr1:101442367 T/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 7.24 0.36 2.99e-12 Refractive astigmatism; LIHC cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg18305652 chr10:134549665 INPP5A 0.51 8.06 0.4 1.31e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7903847 0.596 rs9787426 chr10:99155327 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg07636037 chr3:49044803 WDR6 0.76 12.64 0.56 2.58e-30 Menarche (age at onset); LIHC cis rs3796619 1.000 rs1453605 chr4:1075771 C/T cg27284194 chr4:1044797 NA 0.62 10.38 0.49 3.89e-22 Recombination rate (males); LIHC cis rs6430585 0.528 rs114760827 chr2:136661110 G/A cg15123519 chr2:136567270 LCT -0.36 -5.77 -0.3 1.76e-8 Corneal structure; LIHC cis rs9916302 0.904 rs8079355 chr17:37473018 G/A cg03013999 chr17:37608204 MED1 -0.36 -6.07 -0.31 3.33e-9 Glomerular filtration rate (creatinine); LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg11060661 chr22:24314208 DDT;DDTL 0.61 10.23 0.48 1.37e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs870825 0.698 rs2696046 chr4:185599972 G/A cg04058563 chr4:185651563 MLF1IP -0.69 -6.23 -0.32 1.38e-9 Blood protein levels; LIHC cis rs10744422 0.925 rs2061098 chr12:123349410 T/C cg22842854 chr12:123319900 HIP1R -0.59 -6.9 -0.35 2.48e-11 Schizophrenia; LIHC cis rs6754311 0.773 rs309180 chr2:136614255 A/G cg17750252 chr2:136567154 LCT -0.34 -6.31 -0.32 8.56e-10 Mosquito bite size; LIHC cis rs735860 0.726 rs209490 chr6:53179047 C/T cg10236188 chr6:53219634 NA 0.41 7.41 0.37 1e-12 Glaucoma; LIHC cis rs7618501 0.699 rs2681781 chr3:49898273 A/G cg21467203 chr3:49911342 NA -0.52 -9.03 -0.44 1.29e-17 Intelligence (multi-trait analysis); LIHC cis rs903552 0.736 rs2412008 chr15:102006841 C/T cg25677261 chr15:102009856 PCSK6 -0.51 -6.86 -0.35 3.2e-11 Diabetic kidney disease; LIHC cis rs4934494 0.768 rs58163515 chr10:91397564 T/A cg19698084 chr10:91461284 KIF20B -0.49 -6.68 -0.34 9.61e-11 Red blood cell count; LIHC cis rs798554 0.757 rs960273 chr7:2857876 T/C cg13628971 chr7:2884303 GNA12 0.56 8.09 0.4 1.03e-14 Height; LIHC cis rs5770917 1.000 rs3213445 chr22:51015838 T/C cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.44 -6.4 -0.33 5.07e-10 Narcolepsy; LIHC cis rs6808694 0.568 rs6550401 chr3:20219694 A/C cg00235661 chr3:20228976 SGOL1 0.36 6.35 0.32 6.99e-10 Ischemic stroke; LIHC cis rs1040555 0.516 rs242547 chr20:31418581 T/C cg13636640 chr20:31349939 DNMT3B 0.66 9.81 0.47 3.41e-20 Lymphocyte percentage of white cells; LIHC cis rs8017423 0.872 rs7492857 chr14:90684867 T/G cg14092571 chr14:90743983 NA 0.4 6.25 0.32 1.19e-9 Mortality in heart failure; LIHC cis rs9581857 0.556 rs9581861 chr13:28039991 C/T cg22138327 chr13:27999177 GTF3A 0.48 7.04 0.36 1.04e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs6570726 0.791 rs6923074 chr6:145893332 T/C cg13319975 chr6:146136371 FBXO30 -0.4 -6.5 -0.33 2.91e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.888 rs10745352 chr1:109871787 T/C cg16275483 chr1:110013120 SYPL2 -0.5 -6.28 -0.32 1.03e-9 Intelligence (multi-trait analysis); LIHC cis rs7739232 0.920 rs7748828 chr6:53517643 A/C cg00536792 chr6:53530503 KLHL31 -1.01 -7.33 -0.37 1.72e-12 Hip circumference adjusted for BMI; LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.3e-14 Height; LIHC cis rs3790844 0.876 rs3790847 chr1:200006217 G/T cg07208853 chr1:200005219 NR5A2 0.4 8.71 0.43 1.3e-16 Pancreatic cancer; LIHC cis rs10744422 0.800 rs1696320 chr12:123269814 A/G cg25930673 chr12:123319894 HIP1R -0.81 -10.05 -0.48 5.43e-21 Schizophrenia; LIHC cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.52 8.32 0.41 2.13e-15 Schizophrenia; LIHC cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg22633049 chr21:46681294 NA -0.37 -6.36 -0.33 6.37e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs765787 0.530 rs28756676 chr15:45540360 G/A cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07491203 chr7:155089714 INSIG1 -0.44 -6.81 -0.35 4.51e-11 Cognitive function; LIHC cis rs6450176 0.909 rs6898870 chr5:53293107 G/A ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.23 -0.64 2.38e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs4332037 0.624 rs11764337 chr7:1892309 A/G cg23422044 chr7:1970798 MAD1L1 0.51 6.35 0.32 6.77e-10 Bipolar disorder; LIHC cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.22 -0.45 3.09e-18 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.44 0.37 8.19e-13 Prudent dietary pattern; LIHC cis rs9640161 0.711 rs60268791 chr7:150023800 G/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.86 -0.43 4.45e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs1577917 0.816 rs9353349 chr6:86707725 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.42 7.61 0.38 2.62e-13 Response to antipsychotic treatment; LIHC cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg17971929 chr21:40555470 PSMG1 0.51 7.7 0.38 1.51e-13 Cognitive function; LIHC cis rs7772486 0.790 rs3924498 chr6:146233338 A/T cg23711669 chr6:146136114 FBXO30 -0.71 -12.49 -0.56 9.73e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs9399137 0.507 rs4520025 chr6:135278619 G/T cg24558204 chr6:135376177 HBS1L 0.57 9.57 0.46 2.15e-19 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs2268241 0.938 rs9978223 chr21:34770358 G/A cg14850771 chr21:34775459 IFNGR2 0.86 13.15 0.58 2.98e-32 Obesity-related traits; LIHC cis rs12579753 1.000 rs12827923 chr12:82242067 G/A cg07988820 chr12:82153109 PPFIA2 -0.47 -5.78 -0.3 1.69e-8 Resting heart rate; LIHC cis rs7412746 0.658 rs7521719 chr1:150913134 G/A cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg13152130 chr6:118910203 C6orf204 -0.65 -7.34 -0.37 1.61e-12 Diastolic blood pressure; LIHC cis rs7512552 0.839 rs3896342 chr1:150411312 T/C cg15654264 chr1:150340011 RPRD2 0.69 11.35 0.52 1.55e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs796364 0.806 rs56216998 chr2:200944333 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -8.51 -0.42 5.73e-16 Schizophrenia; LIHC cis rs12926788 0.640 rs12924246 chr16:24844629 A/G cg00339695 chr16:24857497 SLC5A11 0.7 10.49 0.49 1.72e-22 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21864845 chr1:1208426 UBE2J2 0.41 6.69 0.34 8.92e-11 Cognitive function; LIHC cis rs4819052 1.000 rs2838847 chr21:46670958 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.69 9.39 0.45 8.54e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs763121 0.853 rs1062687 chr22:39134715 T/C cg21395723 chr22:39101663 GTPBP1 0.35 5.79 0.3 1.61e-8 Menopause (age at onset); LIHC cis rs12497850 1.000 rs1352420 chr3:48757291 A/G cg06212747 chr3:49208901 KLHDC8B 0.52 6.51 0.33 2.7e-10 Parkinson's disease; LIHC cis rs4268898 0.560 rs2384007 chr2:24514841 A/G cg06627628 chr2:24431161 ITSN2 -0.7 -8.93 -0.43 2.6e-17 Asthma; LIHC cis rs9814567 1.000 rs1814337 chr3:134200682 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.25 -0.55 7.24e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs13217239 0.585 rs114919438 chr6:26963792 T/C cg12292205 chr6:26970375 C6orf41 -0.44 -7.73 -0.39 1.2e-13 Schizophrenia; LIHC trans rs11671005 0.504 rs3794963 chr19:59071051 C/G cg22037779 chr5:139682734 PFDN1 0.57 7.02 0.35 1.18e-11 Mean platelet volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18053345 chr5:37370947 NUP155 0.45 6.63 0.34 1.33e-10 Cognitive function; LIHC cis rs62179067 0.708 rs17363057 chr2:179936172 A/C cg07532576 chr2:179544947 TTN 0.62 5.8 0.3 1.5e-8 Late-onset Alzheimer's disease; LIHC cis rs8180040 0.545 rs9311403 chr3:47138878 T/C cg27129171 chr3:47204927 SETD2 0.57 9.41 0.45 7.47e-19 Colorectal cancer; LIHC cis rs1003719 0.688 rs2000416 chr21:38540089 T/A cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.64 -0.5 5.15e-23 Eye color traits; LIHC trans rs783540 0.835 rs8030185 chr15:83391537 G/A cg18393722 chr15:85113863 UBE2QP1 0.37 6.47 0.33 3.34e-10 Schizophrenia; LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg20607798 chr8:58055168 NA 0.62 7.85 0.39 5.52e-14 Developmental language disorder (linguistic errors); LIHC cis rs12928939 0.727 rs8053623 chr16:71647529 A/G cg03805757 chr16:71968109 PKD1L3 -0.54 -6.3 -0.32 8.95e-10 Post bronchodilator FEV1; LIHC cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg06640241 chr16:89574553 SPG7 0.66 10.45 0.49 2.34e-22 Multiple myeloma (IgH translocation); LIHC trans rs801193 1.000 rs3778909 chr7:66255646 G/C cg26939375 chr7:64535504 NA 0.43 6.82 0.35 4.11e-11 Aortic root size; LIHC cis rs4803468 0.967 rs4605279 chr19:41888131 C/G cg14132834 chr19:41945861 ATP5SL -0.39 -5.76 -0.3 1.86e-8 Height; LIHC trans rs2749592 0.531 rs1208559 chr10:38221370 T/C cg18107078 chr1:162760321 HSD17B7 0.4 6.41 0.33 4.89e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs611744 0.870 rs57723916 chr8:109191433 A/T cg18478394 chr8:109455254 TTC35 0.39 6.8 0.35 4.67e-11 Dupuytren's disease; LIHC cis rs2228479 0.850 rs11640209 chr16:89807828 C/A cg00800038 chr16:89945340 TCF25 -0.61 -8.94 -0.44 2.52e-17 Skin colour saturation; LIHC cis rs10911232 0.507 rs3934578 chr1:183027216 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.55 0.5 1e-22 Hypertriglyceridemia; LIHC cis rs2737618 0.674 rs2258280 chr1:200097648 G/A cg21825944 chr1:200113062 NR5A2 -0.45 -7.69 -0.38 1.56e-13 Uric acid levels; LIHC cis rs6545883 0.965 rs3771261 chr2:61762161 A/G cg15711740 chr2:61764176 XPO1 -0.44 -6.2 -0.32 1.62e-9 Tuberculosis; LIHC cis rs10504229 0.679 rs1596142 chr8:58032406 G/A cg20607798 chr8:58055168 NA 0.46 6.71 0.34 7.96e-11 Developmental language disorder (linguistic errors); LIHC cis rs2948294 0.545 rs11776397 chr8:8115161 C/T cg06636001 chr8:8085503 FLJ10661 0.41 6.43 0.33 4.24e-10 Red cell distribution width; LIHC cis rs11190604 1.000 rs11190602 chr10:102297256 T/C cg07080220 chr10:102295463 HIF1AN 0.53 7.61 0.38 2.76e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.02 0.31 4.58e-9 Menopause (age at onset); LIHC cis rs9303401 0.614 rs34941454 chr17:57102742 T/G cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.41 0.56 1.91e-29 Cognitive test performance; LIHC cis rs904251 0.861 rs1757171 chr6:37487044 T/C cg01843034 chr6:37503916 NA -0.47 -7.37 -0.37 1.33e-12 Cognitive performance; LIHC cis rs10492096 0.853 rs7300092 chr12:6607364 T/C cg13857086 chr12:6580257 VAMP1 0.55 5.9 0.3 8.61e-9 Hip geometry; LIHC cis rs4423214 1.000 rs12797951 chr11:71143266 G/T cg24826892 chr11:71159390 DHCR7 -0.51 -6.7 -0.34 8.75e-11 Vitamin D levels; LIHC cis rs2439831 0.867 rs3101443 chr15:43912372 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.75 0.34 6.39e-11 Lung cancer in ever smokers; LIHC cis rs892961 0.836 rs35077273 chr17:75412415 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs8078723 1.000 rs4794824 chr17:38179290 G/A cg17467752 chr17:38218738 THRA 0.76 13.88 0.6 4.65e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs1975974 0.935 rs67979358 chr17:21723834 G/C cg18423549 chr17:21743878 NA -0.45 -5.94 -0.31 7.19e-9 Psoriasis; LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg18306943 chr3:40428807 ENTPD3 -0.44 -7.82 -0.39 6.78e-14 Renal cell carcinoma; LIHC cis rs2404602 0.692 rs35138393 chr15:76977617 G/A cg03037974 chr15:76606532 NA 0.74 14.64 0.62 5.01e-38 Blood metabolite levels; LIHC cis rs13108904 0.870 rs2291199 chr4:1244267 A/G cg19318889 chr4:1322082 MAEA 0.44 5.86 0.3 1.07e-8 Obesity-related traits; LIHC cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg26818010 chr10:134567672 INPP5A -0.79 -9.59 -0.46 1.84e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg05564831 chr3:52568323 NT5DC2 0.37 6.03 0.31 4.24e-9 Bipolar disorder; LIHC cis rs7131987 0.903 rs11050161 chr12:29420049 A/G cg05697976 chr12:29376483 FAR2 0.31 6.24 0.32 1.33e-9 QT interval; LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg00091569 chr3:40428383 ENTPD3 0.39 6.57 0.33 1.87e-10 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G ch.3.96438232F chr3:94955542 NA -0.37 -6.26 -0.32 1.16e-9 Pancreatic cancer; LIHC cis rs936229 1.000 rs936228 chr15:75132164 T/C cg14664628 chr15:75095509 CSK -0.86 -14.41 -0.61 4.08e-37 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs2304069 1.000 rs7737689 chr5:149396159 C/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.86 11.13 0.52 9.21e-25 HIV-1 control; LIHC cis rs17685 0.712 rs6976236 chr7:75741087 G/T cg01364799 chr7:75623366 TMEM120A -0.48 -7.2 -0.36 3.79e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4332037 0.707 rs62435132 chr7:1891315 C/T cg23422044 chr7:1970798 MAD1L1 -0.54 -6.5 -0.33 2.9e-10 Bipolar disorder; LIHC cis rs4555082 0.834 rs2735816 chr14:105721603 C/G cg10792982 chr14:105748885 BRF1 -0.44 -6.21 -0.32 1.55e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs17685 0.753 rs55812043 chr7:75747241 T/C cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.48e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs25645 0.800 rs34003767 chr17:38194296 A/G cg17467752 chr17:38218738 THRA -0.54 -9.29 -0.45 1.86e-18 Myeloid white cell count; LIHC cis rs9303401 0.659 rs17822735 chr17:56620167 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.13 0.58 3.52e-32 Cognitive test performance; LIHC cis rs61990749 0.597 rs176980 chr14:78198449 C/G cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.51 -0.49 1.47e-22 Fibroblast growth factor basic levels; LIHC cis rs644799 0.932 rs523934 chr11:95641775 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.87 14.99 0.63 2.13e-39 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10861342 1.000 rs1444608 chr12:105559157 A/G cg23923672 chr12:105501055 KIAA1033 0.65 7.57 0.38 3.52e-13 IgG glycosylation; LIHC cis rs2032447 0.530 rs9356996 chr6:26008487 C/A cg15691649 chr6:25882328 NA -0.47 -6.28 -0.32 1.05e-9 Intelligence (multi-trait analysis); LIHC cis rs4919694 1.000 rs75219158 chr10:104747594 C/T cg04362960 chr10:104952993 NT5C2 1.03 7.36 0.37 1.36e-12 Arsenic metabolism; LIHC cis rs12594515 1.000 rs56220882 chr15:45997075 C/G cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs7772486 0.719 rs702307 chr6:145993454 C/G cg13319975 chr6:146136371 FBXO30 0.39 6.38 0.33 5.61e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs72627123 0.867 rs74492048 chr14:74439895 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.48 0.42 6.78e-16 Morning vs. evening chronotype; LIHC cis rs921968 0.509 rs10932782 chr2:219353195 C/T cg02176678 chr2:219576539 TTLL4 0.52 7.09 0.36 7.61e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs12586317 0.525 rs10144430 chr14:35433682 T/A cg05294307 chr14:35346193 BAZ1A -0.47 -7.4 -0.37 1.1e-12 Psoriasis; LIHC trans rs10411161 1.000 rs72626249 chr19:52364875 C/T cg22319618 chr22:45562946 NUP50 -0.54 -7.23 -0.36 3.26e-12 Breast cancer; LIHC cis rs13040088 0.872 rs2295481 chr20:61574727 C/T cg23096297 chr20:61557774 DIDO1 0.84 11.07 0.51 1.52e-24 Menopause (age at onset); LIHC cis rs2204008 0.782 rs11514339 chr12:38236670 G/A cg26384229 chr12:38710491 ALG10B 0.87 10.81 0.5 1.21e-23 Bladder cancer; LIHC cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg09904177 chr6:26538194 HMGN4 0.51 9.64 0.46 1.3e-19 Intelligence (multi-trait analysis); LIHC cis rs4911259 0.552 rs6058926 chr20:31465450 T/C cg13636640 chr20:31349939 DNMT3B -0.61 -10.78 -0.5 1.56e-23 Inflammatory bowel disease; LIHC cis rs965469 0.779 rs6037544 chr20:3290570 A/G cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs2637266 1.000 rs755824 chr10:78381348 A/G cg18941641 chr10:78392320 NA 0.3 6.53 0.33 2.43e-10 Pulmonary function; LIHC cis rs6466055 0.777 rs3801282 chr7:104881530 A/G cg04380332 chr7:105027541 SRPK2 0.36 6.87 0.35 3.07e-11 Schizophrenia; LIHC cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs796364 0.715 rs78988795 chr2:201095739 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -7.14 -0.36 5.56e-12 Schizophrenia; LIHC cis rs919433 0.617 rs700646 chr2:198608511 C/T cg00792783 chr2:198669748 PLCL1 0.45 6.47 0.33 3.45e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4805272 0.626 rs12608533 chr19:29331405 C/G cg04546413 chr19:29218101 NA 0.4 6.79 0.34 5e-11 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg10551016 chr22:41252963 ST13;XPNPEP3 -0.45 -6.47 -0.33 3.42e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12928939 0.637 rs8046629 chr16:71643116 G/A cg03805757 chr16:71968109 PKD1L3 -0.51 -5.84 -0.3 1.22e-8 Post bronchodilator FEV1; LIHC cis rs1005277 0.505 rs1208689 chr10:38097775 C/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.67 -0.57 1.95e-30 Extrinsic epigenetic age acceleration; LIHC cis rs7615952 0.932 rs6438948 chr3:125650045 A/T cg05084668 chr3:125655381 ALG1L 0.49 7.33 0.37 1.66e-12 Blood pressure (smoking interaction); LIHC cis rs7551222 0.749 rs6594019 chr1:204568610 T/C cg20240347 chr1:204465584 NA -0.31 -6.26 -0.32 1.18e-9 Schizophrenia; LIHC cis rs72829446 0.556 rs12936464 chr17:7403942 A/C cg02795151 chr17:7402630 POLR2A -0.54 -6.81 -0.35 4.38e-11 Androgen levels; LIHC cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg27286337 chr10:134555280 INPP5A -0.94 -14.12 -0.61 5.32e-36 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17253792 0.822 rs76918910 chr14:56058762 T/C cg01858014 chr14:56050164 KTN1 -0.78 -8.49 -0.42 6.46e-16 Putamen volume; LIHC cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg03517284 chr6:25882590 NA -0.64 -9.06 -0.44 9.93e-18 Blood metabolite levels; LIHC cis rs6912958 0.684 rs4707382 chr6:88320641 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.84 -0.39 5.87e-14 Monocyte percentage of white cells; LIHC trans rs1814175 0.645 rs847639 chr11:49919603 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs6582630 0.519 rs8189599 chr12:38280748 A/G cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.51e-21 Drug-induced liver injury (flucloxacillin); LIHC cis rs9911578 0.967 rs11079368 chr17:57086473 C/T cg05425664 chr17:57184151 TRIM37 0.6 8.99 0.44 1.67e-17 Intelligence (multi-trait analysis); LIHC cis rs10744422 1.000 rs2292134 chr12:123334033 C/G cg07706471 chr12:123319906 HIP1R -0.62 -8.23 -0.41 4.12e-15 Schizophrenia; LIHC cis rs3741404 0.665 rs594461 chr11:63872543 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 11.06 0.51 1.58e-24 Platelet count; LIHC trans rs875971 0.660 rs3764903 chr7:66098482 G/A cg26939375 chr7:64535504 NA -0.42 -6.84 -0.35 3.73e-11 Aortic root size; LIHC cis rs7412746 0.622 rs11552229 chr1:150783985 T/C cg17724175 chr1:150552817 MCL1 0.47 9.42 0.45 7.01e-19 Melanoma; LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.73 -0.3 2.25e-8 Total body bone mineral density; LIHC trans rs9914544 0.545 rs2386404 chr17:18769349 T/C cg21372672 chr17:16614065 CCDC144A -0.28 -6.79 -0.34 5.11e-11 Educational attainment (years of education); LIHC cis rs2180341 0.960 rs7753913 chr6:127671296 A/G cg27446573 chr6:127587934 RNF146 1.06 16.62 0.67 6.67e-46 Breast cancer; LIHC cis rs2439831 0.867 rs3213991 chr15:43670280 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.76 11.16 0.52 7.29e-25 Lung cancer in ever smokers; LIHC cis rs2153535 0.580 rs1932283 chr6:8477661 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.07 0.4 1.24e-14 Motion sickness; LIHC cis rs6840360 0.571 rs62327269 chr4:152527973 G/C cg22705602 chr4:152727874 NA -0.33 -6.41 -0.33 4.73e-10 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC cis rs798554 0.757 rs1182185 chr7:2872233 A/G cg19717773 chr7:2847554 GNA12 -0.42 -6.4 -0.33 5.13e-10 Height; LIHC cis rs600626 0.636 rs10899109 chr11:75451201 G/A cg24262691 chr11:75473276 NA 0.4 5.95 0.31 6.74e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs1348850 0.914 rs2364854 chr2:178378452 T/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.84 13.48 0.59 1.62e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs7759633 0.800 rs41272110 chr6:161006172 T/G cg06341590 chr4:57624431 NA -0.59 -6.53 -0.33 2.35e-10 Triglycerides; LIHC cis rs11671005 0.610 rs11669345 chr19:59062259 C/T cg25952890 chr19:58913133 NA 0.67 6.86 0.35 3.3e-11 Mean platelet volume; LIHC cis rs1552244 0.882 rs17050699 chr3:10037167 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.58 0.46 2.02e-19 Alzheimer's disease; LIHC cis rs311392 0.554 rs377049 chr8:55097512 A/G cg11783602 chr8:55087084 NA -0.31 -6.16 -0.32 2.05e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs7249142 0.562 rs12980955 chr19:19283646 T/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.4 -6.63 -0.34 1.33e-10 IgG glycosylation; LIHC cis rs67478160 0.643 rs12434686 chr14:104316033 C/T cg01849466 chr14:104193079 ZFYVE21 0.48 7.59 0.38 3.06e-13 Schizophrenia; LIHC cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg10802521 chr3:52805072 NEK4 -0.44 -7.37 -0.37 1.3e-12 Bipolar disorder; LIHC cis rs2072499 0.722 rs61462713 chr1:156161682 C/T cg24450063 chr1:156163899 SLC25A44 0.76 8.22 0.41 4.36e-15 Testicular germ cell tumor; LIHC cis rs2075371 0.796 rs1646645 chr7:134012232 G/T cg11752832 chr7:134001865 SLC35B4 -0.38 -5.87 -0.3 1.01e-8 Mean platelet volume; LIHC cis rs9581857 0.556 rs9581863 chr13:28040171 A/G cg22138327 chr13:27999177 GTF3A 0.48 7.01 0.35 1.26e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs1707322 0.721 rs10890341 chr1:46147240 C/A cg03146154 chr1:46216737 IPP 0.57 9.89 0.47 1.94e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg03874509 chr1:107600012 PRMT6 -0.71 -10.77 -0.5 1.76e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg24693881 chr1:107596107 NA -0.47 -7.73 -0.39 1.24e-13 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10193935 0.901 rs6724626 chr2:42689757 C/G cg27598129 chr2:42591480 NA 0.7 8.97 0.44 2.06e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs5753037 0.702 rs36576 chr22:30206291 C/A cg01021169 chr22:30184971 ASCC2 -0.35 -6.67 -0.34 1.04e-10 Type 1 diabetes; LIHC cis rs3768617 0.966 rs6669796 chr1:183082825 G/C ch.1.3577855R chr1:183094577 LAMC1 0.47 7.48 0.38 6.13e-13 Fuchs's corneal dystrophy; LIHC cis rs7116495 0.609 rs10751191 chr11:71680920 C/T cg10381502 chr11:71823885 C11orf51 -1.02 -8.51 -0.42 5.38e-16 Severe influenza A (H1N1) infection; LIHC cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg22963979 chr7:1858916 MAD1L1 -0.4 -6.47 -0.33 3.43e-10 Bipolar disorder and schizophrenia; LIHC cis rs1552244 0.554 rs3846169 chr3:9997054 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.52 8.55 0.42 4.15e-16 Alzheimer's disease; LIHC cis rs10751667 0.643 rs7394436 chr11:970373 G/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs3809566 1.000 rs10851721 chr15:63332383 T/C cg12160578 chr15:63334699 TPM1 -0.6 -8.6 -0.42 2.96e-16 Platelet count; LIHC cis rs4423214 1.000 rs7935125 chr11:71184190 C/A cg05163923 chr11:71159392 DHCR7 0.88 13.26 0.58 1.1e-32 Vitamin D levels; LIHC cis rs2439831 0.867 rs45585139 chr15:43700427 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.78 10.64 0.5 5.14e-23 Lung cancer in ever smokers; LIHC cis rs644799 0.965 rs11021310 chr11:95502106 A/C cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.81 0.47 3.53e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9858542 0.953 rs6779524 chr3:49450449 C/T cg03060546 chr3:49711283 APEH -0.47 -6.4 -0.33 5.09e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs11702148 0.552 rs6517178 chr21:34888621 C/T cg14850771 chr21:34775459 IFNGR2 -0.48 -7.92 -0.39 3.41e-14 Mean corpuscular hemoglobin; LIHC cis rs12079745 0.623 rs12091844 chr1:169433273 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.7 -6.66 -0.34 1.09e-10 QT interval; LIHC cis rs8077889 0.719 rs2079006 chr17:41865745 C/G cg26893861 chr17:41843967 DUSP3 1.01 17.61 0.69 7.65e-50 Triglycerides; LIHC cis rs7106204 0.514 rs2068454 chr11:24256166 C/G ch.11.24196551F chr11:24239977 NA -0.65 -8.94 -0.44 2.54e-17 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6752107 1.000 rs12994997 chr2:234173503 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.56 8.57 0.42 3.57e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg03721293 chr16:90014378 DEF8 0.39 6.59 0.34 1.63e-10 Skin colour saturation; LIHC cis rs9733 0.519 rs7529194 chr1:150622620 A/T cg18016565 chr1:150552671 MCL1 0.55 10.74 0.5 2.14e-23 Tonsillectomy; LIHC cis rs11673344 0.864 rs55792845 chr19:37498685 T/C cg27390819 chr19:37464633 NA -0.51 -6.21 -0.32 1.57e-9 Obesity-related traits; LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg02782426 chr3:40428986 ENTPD3 0.35 6.32 0.32 8.08e-10 Renal cell carcinoma; LIHC cis rs7618501 0.633 rs9861216 chr3:50059339 A/G cg21467203 chr3:49911342 NA 0.45 8.27 0.41 3.02e-15 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.727 rs6500607 chr16:4503631 C/T cg08645402 chr16:4508243 NA 0.46 9.09 0.44 7.98e-18 Schizophrenia; LIHC cis rs2073300 1.000 rs79255223 chr20:23443559 G/T cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11628318 0.803 rs10138267 chr14:103035432 C/T cg01864069 chr14:103024347 NA -0.57 -9.52 -0.46 3.36e-19 Platelet count; LIHC cis rs9303401 0.580 rs2013166 chr17:56637630 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg13607699 chr17:42295918 UBTF 0.44 7.06 0.36 9.58e-12 Total body bone mineral density; LIHC cis rs763121 0.853 rs9306329 chr22:39072454 C/T cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs7319311 1.000 rs7319311 chr13:111030578 A/G cg05272587 chr13:111038400 COL4A2 0.32 6.73 0.34 7.37e-11 Bipolar disorder and schizophrenia; LIHC cis rs600806 0.854 rs11142 chr1:109897103 A/G cg23091122 chr1:110024289 SYPL2 -0.44 -5.78 -0.3 1.7e-8 Intelligence (multi-trait analysis); LIHC cis rs2073300 0.609 rs6137907 chr20:23344511 C/T cg16736954 chr20:23401023 NAPB 0.73 8.63 0.42 2.36e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg20607798 chr8:58055168 NA 0.72 8.08 0.4 1.15e-14 Developmental language disorder (linguistic errors); LIHC cis rs7551222 0.752 rs4951407 chr1:204558070 G/T cg20240347 chr1:204465584 NA 0.32 6.67 0.34 1.01e-10 Schizophrenia; LIHC cis rs8060686 0.641 rs113896227 chr16:68101480 C/T cg09835421 chr16:68378352 PRMT7 -0.5 -5.84 -0.3 1.18e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs4906332 1.000 rs8012623 chr14:103937086 G/A cg19000871 chr14:103996768 TRMT61A -0.46 -7.88 -0.39 4.53e-14 Coronary artery disease; LIHC cis rs1801251 0.644 rs283473 chr2:233654847 A/G cg08000102 chr2:233561755 GIGYF2 0.76 12.4 0.56 2.07e-29 Coronary artery disease; LIHC cis rs12824058 0.831 rs12831363 chr12:130814013 C/T cg24838063 chr12:130822603 PIWIL1 -0.66 -9.79 -0.47 4.16e-20 Menopause (age at onset); LIHC trans rs1814175 0.791 rs7395713 chr11:49877887 A/G cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.15e-11 Height; LIHC cis rs5758511 0.680 rs1001586 chr22:42670293 G/T cg20195005 chr22:42527684 CYP2D6 0.31 5.83 0.3 1.29e-8 Birth weight; LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg10755058 chr3:40428713 ENTPD3 0.4 6.92 0.35 2.28e-11 Renal cell carcinoma; LIHC cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg20295408 chr7:1910781 MAD1L1 -0.43 -6.21 -0.32 1.52e-9 Schizophrenia; LIHC cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg06238570 chr21:40685208 BRWD1 0.6 7.2 0.36 3.87e-12 Cognitive function; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11283100 chr3:138634282 NA 0.48 6.56 0.33 1.94e-10 Lung function (FEV1/FVC); LIHC cis rs2370759 1.000 rs11008865 chr10:32574842 C/T cg18270830 chr10:32634957 EPC1 0.53 6.44 0.33 4.04e-10 Sexual dysfunction (female); LIHC trans rs61931739 0.500 rs11053268 chr12:34545121 T/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs17376456 0.825 rs10036024 chr5:93074804 C/A cg25358565 chr5:93447407 FAM172A 0.97 7.19 0.36 4.02e-12 Diabetic retinopathy; LIHC cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg03517284 chr6:25882590 NA -0.59 -7.46 -0.37 7.01e-13 Intelligence (multi-trait analysis); LIHC trans rs79976124 0.879 rs78012385 chr6:66618091 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.61 6.27 0.32 1.08e-9 Type 2 diabetes; LIHC cis rs57244997 0.685 rs2226770 chr6:162447251 C/T cg17173639 chr6:162384350 PARK2 0.6 7.45 0.37 7.65e-13 Mosquito bite size; LIHC cis rs10792665 0.575 rs3793983 chr11:82554176 T/A cg24227371 chr11:82718527 RAB30 -0.25 -5.88 -0.3 1e-8 Obesity-related traits; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg11905131 chr22:24372483 LOC391322 -0.63 -9.29 -0.45 1.91e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8044868 0.530 rs2287998 chr16:72059269 C/T cg01557791 chr16:72042693 DHODH 0.39 6.62 0.34 1.42e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg11062466 chr8:58055876 NA 0.52 7.07 0.36 9e-12 Developmental language disorder (linguistic errors); LIHC cis rs74544699 1.000 rs499141 chr4:74768970 A/C cg02530824 chr4:74847766 PF4 0.62 6.49 0.33 3.11e-10 Growth-regulated protein alpha levels; LIHC cis rs1691799 0.867 rs1168356 chr12:66750469 A/G cg16791601 chr12:66731901 HELB -0.52 -12.22 -0.55 9.94e-29 White blood cell count (basophil); LIHC cis rs9311474 0.607 rs4475032 chr3:52560021 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.05 0.44 1.07e-17 Electroencephalogram traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26301639 chr3:93781795 NSUN3;DHFRL1 0.43 6.15 0.32 2.21e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11252926 0.537 rs4881255 chr10:453638 T/C cg16346588 chr10:242978 ZMYND11 0.38 5.85 0.3 1.15e-8 Psychosis in Alzheimer's disease; LIHC cis rs748404 0.660 rs2467741 chr15:43742626 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.11e-13 Lung cancer; LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.04e-14 Height; LIHC cis rs6782228 0.675 rs9841987 chr3:128385142 G/T cg16766828 chr3:128327626 NA -0.43 -6.77 -0.34 5.68e-11 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs860295 1.000 rs10908482 chr1:155713873 T/C cg02153340 chr1:155202674 NA -0.31 -5.79 -0.3 1.56e-8 Body mass index; LIHC cis rs12980942 0.935 rs12980480 chr19:41804655 A/G cg25627403 chr19:41769009 HNRNPUL1 0.49 6.18 0.32 1.8e-9 Coronary artery disease; LIHC cis rs1707322 1.000 rs11211239 chr1:46451947 A/G cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs798554 0.634 rs1182180 chr7:2873279 G/T cg13628971 chr7:2884303 GNA12 0.39 6.07 0.31 3.4e-9 Height; LIHC cis rs2066819 1.000 rs118130855 chr12:56677979 T/A cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs56011263 0.687 rs73221103 chr4:706740 T/C cg17689763 chr4:710664 PCGF3 -0.74 -10.55 -0.5 1e-22 White blood cell count; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg26818010 chr10:134567672 INPP5A 0.76 9.54 0.46 2.75e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs963731 0.579 rs12712630 chr2:39284582 A/G cg04010122 chr2:39346883 SOS1 -0.7 -6.19 -0.32 1.71e-9 Corticobasal degeneration; LIHC cis rs11190604 1.000 rs3750720 chr10:102248884 C/T cg07080220 chr10:102295463 HIF1AN 0.49 6.68 0.34 9.76e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs8032158 0.502 rs2136385 chr15:56235245 C/A cg24530489 chr15:56299380 NA 0.4 5.82 0.3 1.37e-8 Keloid; LIHC cis rs6690583 0.697 rs2012369 chr1:85520845 T/C cg22153463 chr1:85462885 MCOLN2 -0.58 -9.05 -0.44 1.1e-17 Serum sulfate level; LIHC trans rs783540 0.521 rs28719490 chr15:83389440 A/G cg18393722 chr15:85113863 UBE2QP1 0.46 6.62 0.34 1.42e-10 Schizophrenia; LIHC cis rs12474201 0.928 rs1109380 chr2:46924490 G/T cg06386533 chr2:46925753 SOCS5 0.6 6.94 0.35 2e-11 Height; LIHC trans rs11958034 0.539 rs7736963 chr5:18925343 T/G cg08248751 chr6:44043192 NA -0.34 -6.06 -0.31 3.61e-9 Mitochondrial DNA levels; LIHC cis rs9522267 0.502 rs9522281 chr13:112222389 G/A cg10483660 chr13:112241077 NA -0.23 -6.09 -0.31 3.03e-9 Hepatitis; LIHC cis rs13108904 0.934 rs13134106 chr4:1302902 A/G cg06466757 chr4:1255808 NA 0.34 5.73 0.3 2.16e-8 Obesity-related traits; LIHC cis rs7771547 0.573 rs546272 chr6:36398562 G/A cg07856975 chr6:36356162 ETV7 0.36 5.89 0.3 9.23e-9 Platelet distribution width; LIHC cis rs5758511 0.514 rs5751211 chr22:42486056 G/A cg00645731 chr22:42541494 CYP2D7P1 0.52 8.34 0.41 1.84e-15 Birth weight; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg02951695 chr10:134400351 INPP5A 0.43 6.25 0.32 1.24e-9 Longevity; LIHC trans rs28735056 0.565 rs12957336 chr18:77716889 A/G cg05926928 chr17:57297772 GDPD1 -0.41 -6.14 -0.32 2.32e-9 Schizophrenia; LIHC cis rs8056893 0.879 rs3961282 chr16:68365157 A/G cg02226672 chr16:68398533 SMPD3 0.46 6.26 0.32 1.14e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs4665809 1.000 rs2384321 chr2:26290054 A/G cg04944784 chr2:26401820 FAM59B -0.68 -8.47 -0.42 7.14e-16 Gut microbiome composition (summer); LIHC cis rs8180040 0.726 rs61729713 chr3:47027192 A/G cg16586182 chr3:47516702 SCAP 0.45 7.75 0.39 1.04e-13 Colorectal cancer; LIHC cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg20607798 chr8:58055168 NA 0.72 8.08 0.4 1.15e-14 Developmental language disorder (linguistic errors); LIHC cis rs1728785 1.000 rs1170442 chr16:68574064 G/T cg02972257 chr16:68554789 NA -0.55 -6.34 -0.32 7.48e-10 Ulcerative colitis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07920855 chr1:185286635 IVNS1ABP -0.45 -6.56 -0.33 2e-10 Cognitive function; LIHC cis rs79839061 0.610 rs17781499 chr4:889384 C/A cg07828340 chr4:882639 GAK 0.82 6.83 0.35 3.94e-11 Intelligence (multi-trait analysis); LIHC cis rs1790761 0.658 rs666328 chr11:67335538 G/A cg01069141 chr11:67398826 TBX10;NUDT8 0.37 6.65 0.34 1.19e-10 Mean corpuscular volume; LIHC cis rs2404602 0.563 rs12914005 chr15:76765667 A/G cg03037974 chr15:76606532 NA 0.76 14.77 0.62 1.62e-38 Blood metabolite levels; LIHC cis rs7512552 0.780 rs55823828 chr1:150467296 G/C cg15654264 chr1:150340011 RPRD2 0.68 11.01 0.51 2.43e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs8141529 0.778 rs7287806 chr22:29213011 G/A cg15103426 chr22:29168792 CCDC117 0.67 11.43 0.53 7.51e-26 Lymphocyte counts; LIHC cis rs17539620 0.624 rs111868524 chr6:154839960 G/C cg17771515 chr6:154831774 CNKSR3 0.56 5.85 0.3 1.15e-8 Lipoprotein (a) levels; LIHC cis rs4742903 0.870 rs1354894 chr9:106975237 G/A cg14250997 chr9:106856677 SMC2 0.35 5.83 0.3 1.31e-8 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs116248771 0.739 rs1051109 chr3:158415344 T/C cg16708174 chr3:158430962 RARRES1 0.49 6.48 0.33 3.25e-10 diarrhoeal disease at age 2; LIHC cis rs4819052 0.885 rs9980676 chr21:46665430 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.63 0.38 2.35e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1814175 0.588 rs34449937 chr11:49756013 G/A cg15704280 chr7:45808275 SEPT13 -0.97 -20.37 -0.74 5.91e-61 Height; LIHC cis rs7539624 0.588 rs7555491 chr1:223894889 C/T cg07395969 chr1:223900822 CAPN2 -0.48 -5.79 -0.3 1.59e-8 Schizophrenia; LIHC cis rs3008870 0.727 rs2755270 chr1:67474503 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.64 10.76 0.5 1.86e-23 Lymphocyte percentage of white cells; LIHC cis rs9649465 0.935 rs1506641 chr7:123390143 G/A cg03229431 chr7:123269106 ASB15 -0.38 -8.04 -0.4 1.47e-14 Migraine; LIHC cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.579 rs2008449 chr10:38414204 A/T cg27523141 chr10:43048294 ZNF37B -0.37 -6.4 -0.33 5.12e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7587476 0.784 rs62202001 chr2:215690359 C/G cg04530015 chr2:215796436 ABCA12 -0.39 -6.36 -0.33 6.61e-10 Neuroblastoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24222377 chr18:55254128 FECH 0.46 6.38 0.33 5.81e-10 Pancreatic cancer; LIHC cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.35 -0.37 1.45e-12 Bipolar disorder; LIHC cis rs9326248 0.581 rs7120515 chr11:116991926 A/G cg26566898 chr11:117069891 TAGLN 0.43 6.75 0.34 6.47e-11 Blood protein levels; LIHC cis rs12048904 0.619 rs12239082 chr1:101330077 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.63 -10.74 -0.5 2.21e-23 Multiple sclerosis; LIHC cis rs739401 0.611 rs10833048 chr11:3020040 A/G cg25174290 chr11:3078921 CARS 0.61 9.27 0.45 2.2e-18 Longevity; LIHC cis rs6952808 0.534 rs1113736 chr7:1992992 T/C cg21782813 chr7:2030301 MAD1L1 0.48 8.49 0.42 6.29e-16 Bipolar disorder and schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00587304 chr3:172468157 NA 0.41 6.55 0.33 2.13e-10 Cognitive function; LIHC cis rs7131987 0.650 rs16934135 chr12:29483963 T/G cg16970926 chr12:29381810 FAR2 0.29 6.01 0.31 4.78e-9 QT interval; LIHC cis rs250677 0.687 rs250663 chr5:148453117 T/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC cis rs2075371 0.932 rs2598290 chr7:133987736 C/G cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC cis rs8062405 1.000 rs62037369 chr16:28883841 C/T cg07451762 chr16:28383216 NA 0.33 6.13 0.31 2.44e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4629710 0.568 rs9492880 chr6:131565962 G/T cg12606694 chr6:131520996 AKAP7 0.66 7.73 0.39 1.24e-13 Multiple myeloma (IgH translocation); LIHC cis rs9393692 0.905 rs7747133 chr6:26293470 C/T cg00631329 chr6:26305371 NA -0.44 -7.5 -0.38 5.62e-13 Educational attainment; LIHC cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg05368731 chr17:41323189 NBR1 0.71 12.09 0.55 2.96e-28 Menopause (age at onset); LIHC cis rs17125944 0.505 rs118053951 chr14:53259829 G/A cg13660082 chr14:53194042 PSMC6 -0.43 -7.27 -0.37 2.41e-12 Alzheimer's disease (late onset); LIHC cis rs16858210 0.607 rs60244260 chr3:183570734 G/A cg25686905 chr3:183603175 PARL -0.49 -8.57 -0.42 3.53e-16 Menopause (age at onset); LIHC cis rs7149337 0.805 rs2999361 chr14:51605358 G/A cg23942311 chr14:51606299 NA 0.36 7.37 0.37 1.31e-12 Cancer; LIHC cis rs62179067 0.708 rs11895391 chr2:179940586 A/G cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs11971779 0.680 rs10085901 chr7:139108989 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs8180040 0.800 rs56250009 chr3:47279497 G/C cg27129171 chr3:47204927 SETD2 -0.56 -9.11 -0.44 6.87e-18 Colorectal cancer; LIHC cis rs6570726 0.755 rs2092297 chr6:145893765 A/G cg05347473 chr6:146136440 FBXO30 0.39 6.12 0.31 2.53e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs17685 0.725 rs4728548 chr7:75654632 A/T cg19862616 chr7:65841803 NCRNA00174 -0.73 -12.94 -0.57 1.97e-31 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9549367 0.713 rs9549356 chr13:113851633 A/G cg18105134 chr13:113819100 PROZ -0.79 -13.44 -0.59 2.35e-33 Platelet distribution width; LIHC cis rs7098414 0.511 rs10788603 chr10:82148137 G/T cg00277334 chr10:82204260 NA -0.59 -9.7 -0.46 8.44e-20 Post bronchodilator FEV1; LIHC cis rs7945718 1.000 rs7945718 chr11:12748819 A/G cg25843174 chr11:12811716 TEAD1 0.36 8.24 0.41 3.64e-15 Educational attainment (years of education); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07395075 chr16:56642428 MT2A 0.39 6.07 0.31 3.32e-9 Pancreatic cancer; LIHC cis rs798554 1.000 rs798545 chr7:2762386 C/T cg19346786 chr7:2764209 NA -0.45 -6.82 -0.35 4.05e-11 Height; LIHC cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs912057 0.526 rs1294400 chr6:6733421 A/G cg06612196 chr6:6737390 NA -0.46 -8.44 -0.42 9.35e-16 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC trans rs3780486 0.522 rs1328898 chr9:33163271 A/G cg20290983 chr6:43655470 MRPS18A 0.83 15.24 0.64 2.14e-40 IgG glycosylation; LIHC trans rs11722228 0.508 rs2241472 chr4:10085902 C/G cg26043149 chr18:55253948 FECH 0.96 14.01 0.6 1.41e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg08280861 chr8:58055591 NA 0.54 5.86 0.3 1.06e-8 Developmental language disorder (linguistic errors); LIHC cis rs2303759 0.709 rs8102574 chr19:49828897 A/G cg05022225 chr19:49866942 DKKL1;TEAD2 0.54 8.02 0.4 1.73e-14 Multiple sclerosis; LIHC cis rs17125944 0.686 rs2025634 chr14:53336017 C/T cg00686598 chr14:53173677 PSMC6 -0.74 -8.52 -0.42 5.34e-16 Alzheimer's disease (late onset); LIHC cis rs6748734 0.857 rs10933638 chr2:241794655 G/A cg08694578 chr2:241835147 C2orf54 -0.52 -8.06 -0.4 1.32e-14 Urinary metabolites; LIHC cis rs1707322 0.752 rs4607935 chr1:46117161 C/T cg03146154 chr1:46216737 IPP 0.57 9.89 0.47 1.96e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs861318 0.702 rs12098223 chr1:159011694 C/T cg11003133 chr1:159046391 AIM2 -0.32 -6.46 -0.33 3.62e-10 Obesity-related traits; LIHC cis rs67478160 0.634 rs1955660 chr14:104229985 C/T cg08213375 chr14:104286397 PPP1R13B 0.51 9.69 0.46 8.57e-20 Schizophrenia; LIHC cis rs8084351 0.539 rs4129323 chr18:50605360 G/C cg24270629 chr18:50823537 DCC 0.46 7.05 0.36 9.72e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs78456975 0.607 rs73909625 chr2:1541934 A/G cg01028140 chr2:1542097 TPO -0.58 -6.71 -0.34 8.18e-11 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs9942416 0.503 rs253393 chr5:74929647 G/A cg19683494 chr5:74908142 NA -0.48 -6.21 -0.32 1.55e-9 Age-related disease endophenotypes; LIHC cis rs2806561 1.000 rs681753 chr1:23515216 T/C cg19743168 chr1:23544995 NA 0.4 7.67 0.38 1.8e-13 Height; LIHC cis rs9902453 0.817 rs1038089 chr17:28178724 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.32 0.55 4.05e-29 Coffee consumption (cups per day); LIHC cis rs8180040 0.726 rs6785790 chr3:47146932 C/T cg02527881 chr3:46936655 PTH1R -0.31 -6.05 -0.31 3.72e-9 Colorectal cancer; LIHC cis rs16958440 1.000 rs57928699 chr18:44645593 T/A cg17192377 chr18:44677553 HDHD2 0.6 6.76 0.34 5.88e-11 Sitting height ratio; LIHC cis rs7520050 0.807 rs6429576 chr1:46216575 T/C cg24296786 chr1:45957014 TESK2 -0.4 -5.88 -0.3 9.62e-9 Red blood cell count;Reticulocyte count; LIHC cis rs8064454 0.764 rs11658063 chr17:36103872 C/G cg04198914 chr17:36106025 HNF1B 0.36 6.1 0.31 2.89e-9 Prostate cancer; LIHC cis rs8016982 0.520 rs17111601 chr14:81717808 C/T cg01989461 chr14:81687754 GTF2A1 -0.39 -6.27 -0.32 1.08e-9 Schizophrenia; LIHC cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.78 11.68 0.53 9.79e-27 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6701037 1.000 rs6425323 chr1:175125036 C/T cg17845761 chr1:175162550 KIAA0040 -0.35 -5.74 -0.3 2.11e-8 Alcohol dependence; LIHC cis rs3936840 0.861 rs1044502 chr14:102965897 G/A cg10241871 chr14:102965420 TECPR2 -0.47 -7.46 -0.37 7.03e-13 Plateletcrit; LIHC cis rs12048904 0.619 rs10875346 chr1:101328083 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.47 6.81 0.35 4.45e-11 Multiple sclerosis; LIHC cis rs67981189 0.574 rs2526884 chr14:71367967 G/A cg15816911 chr14:71606274 NA -0.4 -6.41 -0.33 4.76e-10 Schizophrenia; LIHC cis rs10847980 0.590 rs75794148 chr12:123287329 C/G cg25930673 chr12:123319894 HIP1R 1.09 11.71 0.53 7.59e-27 Adiponectin levels; LIHC cis rs7116495 0.867 rs562621 chr11:71579213 C/G cg26138937 chr11:71823887 C11orf51 0.7 6.86 0.35 3.27e-11 Severe influenza A (H1N1) infection; LIHC cis rs6424115 1.000 rs6697805 chr1:24151996 C/A cg10978503 chr1:24200527 CNR2 -0.38 -8.92 -0.43 2.83e-17 Immature fraction of reticulocytes; LIHC cis rs10791097 0.568 rs4411284 chr11:130738568 A/C cg22079354 chr11:130786696 SNX19 0.41 5.9 0.3 8.98e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs174601 0.582 rs108499 chr11:61547237 C/T cg27386326 chr11:61587980 NA 0.68 13.74 0.6 1.64e-34 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs6500602 0.627 rs1641866 chr16:4593040 A/C cg08645402 chr16:4508243 NA 0.38 6.4 0.33 5.17e-10 Schizophrenia; LIHC cis rs2576037 0.526 rs4890707 chr18:44497724 C/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.61 -0.34 1.49e-10 Personality dimensions; LIHC cis rs16944613 0.588 rs6416553 chr15:91135411 A/G cg26821196 chr15:91095069 CRTC3 -0.44 -7.31 -0.37 1.86e-12 Colorectal cancer; LIHC cis rs1707322 0.717 rs1135812 chr1:46095272 T/C cg03146154 chr1:46216737 IPP 0.55 9.23 0.45 2.92e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.92 9.4 0.45 8.21e-19 Platelet count; LIHC cis rs9534288 0.797 rs2094246 chr13:46602163 C/T cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs782590 0.902 rs782600 chr2:55848040 T/C cg03859395 chr2:55845619 SMEK2 0.9 15.68 0.65 3.88e-42 Metabolic syndrome; LIHC cis rs4970966 0.855 rs11204701 chr1:150662179 A/T cg18016565 chr1:150552671 MCL1 -0.43 -6.45 -0.33 3.87e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs1865760 0.622 rs9295685 chr6:26071725 G/C cg18357526 chr6:26021779 HIST1H4A 0.45 6.59 0.34 1.63e-10 Height; LIHC trans rs12478296 0.591 rs12468297 chr2:242996474 A/G cg01596870 chr19:55963115 NA -0.67 -10.74 -0.5 2.18e-23 Obesity-related traits; LIHC cis rs2153535 0.526 rs9406179 chr6:8538224 G/A cg21535247 chr6:8435926 SLC35B3 0.63 8.19 0.4 5.35e-15 Motion sickness; LIHC cis rs7551222 0.749 rs2887429 chr1:204565012 G/T cg20240347 chr1:204465584 NA -0.31 -6.25 -0.32 1.21e-9 Schizophrenia; LIHC cis rs950169 0.922 rs17531523 chr15:85132449 C/G cg17507749 chr15:85114479 UBE2QP1 0.77 8.63 0.42 2.34e-16 Schizophrenia; LIHC cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg04944784 chr2:26401820 FAM59B 0.72 9.21 0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs9790314 0.846 rs6791213 chr3:161033721 A/G cg03342759 chr3:160939853 NMD3 -0.79 -12.71 -0.57 1.42e-30 Morning vs. evening chronotype; LIHC cis rs2463822 0.925 rs1881535 chr11:62121623 C/T cg06239285 chr11:62104954 ASRGL1 0.91 6.85 0.35 3.55e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs3849570 0.695 rs6792696 chr3:81874009 G/A cg07356753 chr3:81810745 GBE1 -0.52 -8.28 -0.41 2.88e-15 Waist circumference;Body mass index; LIHC cis rs3768617 0.510 rs10752904 chr1:183101038 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs2637266 1.000 rs2130799 chr10:78322922 C/T cg18941641 chr10:78392320 NA 0.28 6.01 0.31 4.86e-9 Pulmonary function; LIHC cis rs4665809 1.000 rs1550381 chr2:26266946 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.68 -0.42 1.68e-16 Gut microbiome composition (summer); LIHC cis rs2439831 0.867 rs4583210 chr15:43660925 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.18 0.52 5.88e-25 Lung cancer in ever smokers; LIHC cis rs1691799 0.777 rs11176145 chr12:66719795 A/G cg16791601 chr12:66731901 HELB 0.4 7.77 0.39 9.55e-14 White blood cell count (basophil); LIHC cis rs798554 0.757 rs2533878 chr7:2878707 A/G cg13628971 chr7:2884303 GNA12 -0.5 -6.96 -0.35 1.74e-11 Height; LIHC cis rs6951245 0.744 rs10265758 chr7:1172518 C/T cg24642844 chr7:1081250 C7orf50 -0.6 -6.71 -0.34 8.2e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10493773 0.609 rs11161656 chr1:86182414 A/G cg17807903 chr1:86174739 ZNHIT6 -0.61 -11.93 -0.54 1.11e-27 Urate levels in overweight individuals; LIHC cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg11890956 chr21:40555474 PSMG1 1.03 14.83 0.63 8.98e-39 Cognitive function; LIHC cis rs798554 0.757 rs1182198 chr7:2862906 C/T cg19346786 chr7:2764209 NA -0.48 -6.83 -0.35 3.85e-11 Height; LIHC cis rs2439831 0.867 rs16957632 chr15:43642897 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02767759 chr16:30366751 CD2BP2 0.47 7.2 0.36 3.79e-12 Cognitive function; LIHC cis rs477692 0.618 rs7080419 chr10:131455235 A/G cg19680672 chr10:131412579 MGMT -0.43 -6.59 -0.34 1.68e-10 Response to temozolomide; LIHC cis rs6430585 0.528 rs79826902 chr2:136670419 G/A cg07169764 chr2:136633963 MCM6 1.29 21.48 0.76 2.15e-65 Corneal structure; LIHC cis rs8017423 0.647 rs12882575 chr14:90820454 C/G cg04374321 chr14:90722782 PSMC1 -0.5 -7.39 -0.37 1.12e-12 Mortality in heart failure; LIHC trans rs17685 0.712 rs1859792 chr7:75789264 T/C cg19862616 chr7:65841803 NCRNA00174 0.79 14.47 0.62 2.41e-37 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg04944784 chr2:26401820 FAM59B -0.57 -7.59 -0.38 3.17e-13 Gut microbiome composition (summer); LIHC cis rs6723226 1.000 rs6723226 chr2:32849207 C/T cg02381751 chr2:32503542 YIPF4 0.66 9.7 0.46 8.37e-20 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.656 rs9429172 chr1:46092476 C/G cg03146154 chr1:46216737 IPP -0.55 -9.08 -0.44 9e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6120849 0.754 rs17319032 chr20:33643296 T/C cg24642439 chr20:33292090 TP53INP2 0.66 7.21 0.36 3.58e-12 Protein C levels; LIHC cis rs35110281 0.591 rs162390 chr21:44936826 C/T cg21573476 chr21:45109991 RRP1B -0.47 -8.41 -0.41 1.13e-15 Mean corpuscular volume; LIHC cis rs9611519 0.894 rs9623320 chr22:41478482 G/A cg03806693 chr22:41940476 POLR3H -0.72 -8.14 -0.4 7.37e-15 Neuroticism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20824237 chr3:99979579 TBC1D23 0.39 6.07 0.31 3.47e-9 Cognitive function; LIHC cis rs60871478 1.000 rs62432242 chr7:797715 G/A cg13844804 chr7:814759 HEATR2 0.45 6.04 0.31 3.99e-9 Cerebrospinal P-tau181p levels; LIHC cis rs6424115 0.729 rs586173 chr1:24055718 A/G cg15997130 chr1:24165203 NA -0.33 -6.7 -0.34 8.68e-11 Immature fraction of reticulocytes; LIHC trans rs35110281 0.755 rs4819270 chr21:45020919 G/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.11 0.31 2.7e-9 Mean corpuscular volume; LIHC trans rs9951602 0.512 rs4798995 chr18:76654344 T/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs1267820 chr7:66050295 C/G cg12463550 chr7:65579703 CRCP 0.67 6.9 0.35 2.49e-11 Diabetic kidney disease; LIHC cis rs72781680 0.800 rs6718635 chr2:24066183 A/C cg08917208 chr2:24149416 ATAD2B 0.99 8.7 0.43 1.39e-16 Lymphocyte counts; LIHC cis rs1401999 1.000 rs1401999 chr3:183678342 C/G cg05044414 chr3:183734942 ABCC5 0.35 6.07 0.31 3.47e-9 Anterior chamber depth; LIHC cis rs9470366 0.883 rs7756236 chr6:36627053 A/G cg08179530 chr6:36648295 CDKN1A 0.57 7.0 0.35 1.38e-11 QRS duration; LIHC cis rs7927771 0.965 rs11039416 chr11:47846711 G/A cg20307385 chr11:47447363 PSMC3 -0.44 -5.74 -0.3 2.04e-8 Subjective well-being; LIHC cis rs1577917 0.916 rs12206726 chr6:86499716 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.86 -0.3 1.09e-8 Response to antipsychotic treatment; LIHC trans rs2243480 1.000 rs4718315 chr7:65648541 T/C cg10756647 chr7:56101905 PSPH -1.07 -13.17 -0.58 2.44e-32 Diabetic kidney disease; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg20078067 chr8:12612870 LONRF1 0.71 6.66 0.34 1.12e-10 Musician's dystonia; LIHC cis rs875971 0.964 rs778721 chr7:65845397 C/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs68170813 0.559 rs3815148 chr7:106938420 G/T cg02696742 chr7:106810147 HBP1 0.52 6.16 0.32 2.06e-9 Coronary artery disease; LIHC cis rs8060686 0.516 rs1975802 chr16:68285847 A/G cg05110241 chr16:68378359 PRMT7 -0.56 -6.77 -0.34 5.72e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs3820068 0.705 rs4646110 chr1:15817318 A/T cg17385448 chr1:15911702 AGMAT 0.36 6.11 0.31 2.74e-9 Systolic blood pressure; LIHC cis rs4713118 0.621 rs10484403 chr6:28033523 A/G cg16479474 chr6:28041457 NA 0.45 6.68 0.34 9.73e-11 Parkinson's disease; LIHC cis rs7772486 0.875 rs9399572 chr6:146362945 T/G cg23711669 chr6:146136114 FBXO30 0.6 10.67 0.5 3.87e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7312774 0.881 rs7309260 chr12:107313254 T/A cg16260113 chr12:107380972 MTERFD3 0.77 10.08 0.48 4.37e-21 Severe influenza A (H1N1) infection; LIHC cis rs10504073 0.647 rs4873098 chr8:50021041 T/C cg00325661 chr8:49890786 NA 0.31 7.2 0.36 3.98e-12 Blood metabolite ratios; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg16600020 chr8:30210405 NA 0.31 6.07 0.31 3.35e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs17685 0.725 rs7795291 chr7:75725206 C/A cg19862616 chr7:65841803 NCRNA00174 0.9 18.08 0.7 9.01e-52 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4268898 0.662 rs12052954 chr2:24425620 C/T cg06627628 chr2:24431161 ITSN2 0.72 9.81 0.47 3.57e-20 Asthma; LIHC cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg13395646 chr4:1353034 KIAA1530 -0.4 -6.28 -0.32 1.06e-9 Obesity-related traits; LIHC cis rs763121 0.853 rs35522482 chr22:39063015 C/A cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15001132 chr13:25875890 NUPL1 0.5 6.72 0.34 7.69e-11 Lung function (FEV1/FVC); LIHC cis rs8062405 1.000 rs28403629 chr16:28854769 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg26818010 chr10:134567672 INPP5A -0.78 -9.56 -0.46 2.43e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7534824 0.625 rs17448356 chr1:101345093 C/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 6.67 0.34 1.01e-10 Refractive astigmatism; LIHC cis rs6840360 0.571 rs11099823 chr4:152510565 T/G cg22705602 chr4:152727874 NA -0.31 -6.2 -0.32 1.63e-9 Intelligence (multi-trait analysis); LIHC cis rs1570884 0.516 rs2146144 chr13:50170245 C/T cg08779649 chr13:50194554 NA 0.36 6.45 0.33 3.8e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs332507 0.830 rs13069961 chr3:124358715 A/G cg05980111 chr3:124395277 KALRN 0.4 6.15 0.32 2.2e-9 Plateletcrit; LIHC cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg26818010 chr10:134567672 INPP5A -0.78 -9.65 -0.46 1.18e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7937682 0.889 rs1784787 chr11:111486125 T/A cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs7542091 0.704 rs7537294 chr1:210043777 A/G cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs7772486 0.806 rs4075695 chr6:146250959 A/G cg23711669 chr6:146136114 FBXO30 -0.59 -10.44 -0.49 2.56e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs1336900 0.513 rs56253522 chr1:150614869 C/A cg18016565 chr1:150552671 MCL1 0.58 11.01 0.51 2.38e-24 Blood protein levels; LIHC cis rs9325144 0.647 rs11169222 chr12:39105210 C/T cg26384229 chr12:38710491 ALG10B -0.41 -5.89 -0.3 9.16e-9 Morning vs. evening chronotype; LIHC cis rs6499255 0.904 rs7187653 chr16:69562838 G/C cg15192750 chr16:69999425 NA 0.46 6.56 0.33 1.95e-10 IgE levels; LIHC cis rs6570726 0.791 rs9373466 chr6:145912016 T/C cg13319975 chr6:146136371 FBXO30 -0.4 -6.31 -0.32 8.87e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2404602 0.583 rs12913096 chr15:76551852 C/T cg03037974 chr15:76606532 NA 0.88 22.87 0.78 7.02e-71 Blood metabolite levels; LIHC cis rs79839061 0.520 rs2279187 chr4:875529 C/T cg07828340 chr4:882639 GAK 0.84 7.15 0.36 5.41e-12 Intelligence (multi-trait analysis); LIHC cis rs4969178 1.000 rs7212201 chr17:76393896 C/A cg20026190 chr17:76395443 PGS1 0.45 7.15 0.36 5.31e-12 HDL cholesterol levels; LIHC cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs8067545 0.750 rs4924805 chr17:19997205 C/G cg13482628 chr17:19912719 NA 0.5 8.18 0.4 5.77e-15 Schizophrenia; LIHC cis rs769267 1.000 rs769267 chr19:19446936 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.6 9.72 0.47 7.14e-20 Tonsillectomy; LIHC cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs7727544 0.735 rs270605 chr5:131651811 C/T cg07395648 chr5:131743802 NA -0.32 -6.55 -0.33 2.14e-10 Blood metabolite levels; LIHC trans rs66887589 0.807 rs7694483 chr4:120405929 T/A cg25214090 chr10:38739885 LOC399744 0.4 6.61 0.34 1.48e-10 Diastolic blood pressure; LIHC cis rs4819052 0.851 rs2838826 chr21:46655785 A/G cg22633049 chr21:46681294 NA -0.35 -5.79 -0.3 1.6e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7762018 0.607 rs79728466 chr6:170046405 T/C cg19338460 chr6:170058176 WDR27 -0.9 -9.03 -0.44 1.28e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11764590 0.694 rs4721359 chr7:2104951 A/G cg23043544 chr7:2124092 MAD1L1 -0.39 -6.35 -0.32 6.8e-10 Neuroticism; LIHC cis rs6977660 1.000 rs12531373 chr7:19816825 A/C cg07541023 chr7:19748670 TWISTNB 0.36 5.72 0.3 2.33e-8 Thyroid stimulating hormone; LIHC cis rs539514 0.690 rs776527 chr13:76317794 G/A cg04757411 chr13:76259545 LMO7 -0.47 -8.25 -0.41 3.5e-15 Type 1 diabetes; LIHC cis rs116095464 0.558 rs6869925 chr5:264036 A/G cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs2153535 0.580 rs1832100 chr6:8446956 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.04 0.4 1.5e-14 Motion sickness; LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg22907277 chr7:1156413 C7orf50 0.59 8.92 0.43 2.96e-17 Longevity;Endometriosis; LIHC cis rs2932538 0.961 rs2932529 chr1:113193364 G/A cg22162597 chr1:113214053 CAPZA1 -0.73 -9.83 -0.47 2.91e-20 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs858239 0.601 rs10239760 chr7:23149950 C/T cg18081818 chr7:23246105 NA -0.39 -5.8 -0.3 1.48e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs7412746 0.634 rs2124952 chr1:150923774 T/A cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs11951515 0.508 rs1366410 chr5:43601610 C/A cg01983248 chr5:43482804 C5orf28 -0.37 -6.12 -0.31 2.54e-9 Metabolite levels (X-11787); LIHC cis rs2607426 0.681 rs2233156 chr19:41281700 C/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.54 -6.03 -0.31 4.26e-9 Blood protein levels; LIHC cis rs3768617 0.510 rs7414273 chr1:183075017 T/C ch.1.3577855R chr1:183094577 LAMC1 0.62 10.93 0.51 4.56e-24 Fuchs's corneal dystrophy; LIHC cis rs4808199 0.948 rs2023883 chr19:19405480 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.7 0.38 1.44e-13 Nonalcoholic fatty liver disease; LIHC cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg05552183 chr6:42928497 GNMT -0.79 -11.79 -0.54 3.75e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6690583 1.000 rs6690583 chr1:85466337 A/G cg22153463 chr1:85462885 MCOLN2 -0.47 -6.37 -0.33 6.12e-10 Serum sulfate level; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.4 -0.33 5e-10 Total body bone mineral density; LIHC cis rs1475911 0.507 rs11702347 chr21:43526454 C/T cg24372256 chr21:43528868 UMODL1;C21orf128 -0.43 -6.28 -0.32 1.01e-9 IgG glycosylation; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs34375054 0.573 rs12811438 chr12:125653490 C/T cg25124228 chr12:125621409 AACS -0.43 -6.66 -0.34 1.09e-10 Post bronchodilator FEV1/FVC ratio; LIHC trans rs11039798 0.687 rs11499938 chr11:48957297 G/A cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC cis rs7520050 0.807 rs4660312 chr1:46110572 A/G cg24296786 chr1:45957014 TESK2 -0.39 -5.88 -0.3 9.88e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1443512 0.812 rs1867299 chr12:54329975 T/C cg25024717 chr12:54324583 NA -0.32 -6.3 -0.32 8.9e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs2304069 0.909 rs2544931 chr5:149367837 C/G cg12661370 chr5:149340060 SLC26A2 -0.57 -6.8 -0.35 4.61e-11 HIV-1 control; LIHC trans rs1005277 0.579 rs1740737 chr10:38499365 G/T cg23533926 chr12:111358616 MYL2 -0.33 -6.26 -0.32 1.12e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3820068 0.581 rs72645861 chr1:15920314 A/G cg17385448 chr1:15911702 AGMAT 0.36 6.14 0.32 2.24e-9 Systolic blood pressure; LIHC cis rs2901460 0.509 rs17573253 chr2:62101915 C/T cg02183531 chr2:62113199 CCT4 0.42 6.21 0.32 1.53e-9 Mean corpuscular volume; LIHC cis rs3770081 0.793 rs7608262 chr2:86225471 A/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -8.04 -0.4 1.46e-14 Facial emotion recognition (sad faces); LIHC cis rs921968 0.565 rs6757772 chr2:219618497 T/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9814567 1.000 rs6439487 chr3:134260860 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11105298 0.891 rs10777162 chr12:89830523 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.61 -6.73 -0.34 7.17e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs4906332 1.000 rs4906327 chr14:103929039 C/T cg17675199 chr6:35436792 RPL10A 0.34 6.63 0.34 1.32e-10 Coronary artery disease; LIHC cis rs2412488 0.815 rs6843529 chr4:54355854 T/C cg22241045 chr4:54363911 LNX1 0.42 6.78 0.34 5.45e-11 DNA methylation (variation); LIHC cis rs9303401 0.659 rs35082010 chr17:56936867 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.34 0.58 5.91e-33 Cognitive test performance; LIHC cis rs9470366 0.883 rs12199346 chr6:36641546 C/A cg08179530 chr6:36648295 CDKN1A 0.56 6.59 0.34 1.7e-10 QRS duration; LIHC trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg16836995 chr17:43662488 NA -0.69 -7.21 -0.36 3.64e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs8073060 0.586 rs225305 chr17:33921160 C/T cg19694781 chr19:47549865 TMEM160 -1.24 -12.83 -0.57 5.1e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7927592 0.956 rs11228269 chr11:68289796 A/G cg20283391 chr11:68216788 NA -0.51 -7.66 -0.38 1.97e-13 Total body bone mineral density; LIHC cis rs7131987 0.650 rs4331146 chr12:29440083 G/T cg21522988 chr12:29376872 FAR2 0.26 5.95 0.31 6.61e-9 QT interval; LIHC cis rs13217239 0.597 rs9467978 chr6:27024558 A/G cg12292205 chr6:26970375 C6orf41 -0.44 -7.41 -0.37 9.95e-13 Schizophrenia; LIHC cis rs5769765 0.773 rs9616395 chr22:50317803 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -8.76 -0.43 9.02e-17 Schizophrenia; LIHC cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg03517284 chr6:25882590 NA 0.94 12.82 0.57 5.38e-31 Blood metabolite levels; LIHC cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs16958440 0.867 rs78585258 chr18:44677729 T/A cg17192377 chr18:44677553 HDHD2 0.93 8.75 0.43 1.01e-16 Sitting height ratio; LIHC cis rs910316 1.000 rs175492 chr14:75545220 A/C cg11812906 chr14:75593930 NEK9 0.76 15.2 0.63 3.14e-40 Height; LIHC cis rs919433 0.679 rs10931788 chr2:198531084 A/G cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg22963979 chr7:1858916 MAD1L1 -0.44 -7.03 -0.36 1.09e-11 Bipolar disorder and schizophrenia; LIHC cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg19318889 chr4:1322082 MAEA 0.41 5.94 0.31 6.9e-9 Obesity-related traits; LIHC cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg11764359 chr7:65958608 NA 0.6 6.1 0.31 2.92e-9 Diabetic kidney disease; LIHC cis rs2051211 0.947 rs73065216 chr3:38524194 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.55 -6.28 -0.32 1.01e-9 QRS duration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09337544 chr22:38857452 NA 0.43 6.36 0.33 6.31e-10 Lung function (FEV1/FVC); LIHC cis rs9916302 0.861 rs9903363 chr17:37499604 C/G cg07936489 chr17:37558343 FBXL20 0.84 13.6 0.59 5.67e-34 Glomerular filtration rate (creatinine); LIHC cis rs2230307 0.536 rs560659 chr1:100523536 A/G cg24955406 chr1:100503596 HIAT1 -0.62 -6.34 -0.32 7.1e-10 Carotid intima media thickness; LIHC cis rs16866061 1.000 rs2047134 chr2:225347713 A/C cg12698349 chr2:225449008 CUL3 0.71 11.89 0.54 1.63e-27 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs1443512 0.812 rs1975470 chr12:54336841 G/A cg12374095 chr12:54320830 NA 0.4 5.79 0.3 1.6e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs2153535 0.601 rs2327054 chr6:8443130 T/C cg23788917 chr6:8435910 SLC35B3 0.59 8.37 0.41 1.53e-15 Motion sickness; LIHC cis rs6450176 1.000 rs9687611 chr5:53300288 C/T ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs2395128 0.765 rs1880690 chr10:76664682 G/A cg24341800 chr11:107992076 ACAT1 0.49 6.04 0.31 3.95e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs734999 0.545 rs4648565 chr1:2570023 A/G cg18854424 chr1:2615690 NA -0.33 -7.16 -0.36 4.97e-12 Ulcerative colitis; LIHC cis rs920590 0.758 rs1907799 chr8:19664668 A/G cg17834443 chr8:19674713 INTS10 -0.48 -7.28 -0.37 2.31e-12 Acute lymphoblastic leukemia (childhood); LIHC trans rs9460578 0.634 rs9465912 chr6:20826011 G/A cg07086918 chr5:176784688 RGS14 -0.43 -6.07 -0.31 3.32e-9 Breast cancer; LIHC cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs4927850 0.918 rs4361313 chr3:195752260 A/G cg21051086 chr3:73046214 PPP4R2 -0.38 -6.17 -0.32 1.95e-9 Pancreatic cancer; LIHC cis rs2976388 0.590 rs7828042 chr8:143819383 A/G cg06565975 chr8:143823917 SLURP1 -0.41 -7.72 -0.39 1.27e-13 Urinary tract infection frequency; LIHC cis rs15676 0.783 rs7858732 chr9:131563540 A/G cg00228799 chr9:131580591 ENDOG -0.46 -6.51 -0.33 2.7e-10 Blood metabolite levels; LIHC cis rs1707322 0.721 rs10430124 chr1:46221617 C/T cg03146154 chr1:46216737 IPP 0.59 10.09 0.48 3.98e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs6866721 0.791 rs35637069 chr5:116216123 C/G cg07571379 chr11:134631427 NA -0.28 -6.07 -0.31 3.31e-9 Body mass index; LIHC cis rs611744 0.967 rs686584 chr8:109192357 G/A cg18478394 chr8:109455254 TTC35 0.4 6.87 0.35 3.09e-11 Dupuytren's disease; LIHC cis rs150647904 1 rs150647904 chr1:54839485 T/TCAG cg17417004 chr1:54819992 SSBP3 0.56 7.56 0.38 3.67e-13 Platelet distribution width; LIHC cis rs2153535 0.541 rs945304 chr6:8442892 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.81e-14 Motion sickness; LIHC cis rs2204008 0.599 rs2320526 chr12:38220405 T/A cg26384229 chr12:38710491 ALG10B 0.82 10.56 0.5 9.48e-23 Bladder cancer; LIHC cis rs950169 0.920 rs12915390 chr15:84792069 T/C cg03959625 chr15:84868606 LOC388152 0.48 6.02 0.31 4.4e-9 Schizophrenia; LIHC trans rs7618501 0.815 rs3819325 chr3:49843723 T/C cg21582582 chr3:182698605 DCUN1D1 0.53 6.91 0.35 2.33e-11 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.927 rs1886007 chr20:60581049 G/A cg13770153 chr20:60521292 NA -0.33 -6.46 -0.33 3.68e-10 Body mass index; LIHC trans rs873946 0.564 rs2803992 chr10:134550882 T/C cg02418909 chr7:4811322 NA -0.45 -6.11 -0.31 2.69e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17685 0.587 rs1623759 chr7:75724679 A/T cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.76e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs986417 0.748 rs4899011 chr14:60986698 A/G cg27398547 chr14:60952738 C14orf39 0.76 8.99 0.44 1.74e-17 Gut microbiota (bacterial taxa); LIHC cis rs903552 0.736 rs2132196 chr15:102007089 A/G cg06707286 chr15:102010195 PCSK6 -0.52 -7.48 -0.37 6.46e-13 Diabetic kidney disease; LIHC cis rs60871478 0.730 rs62432226 chr7:792973 T/C cg05535760 chr7:792225 HEATR2 0.97 13.24 0.58 1.36e-32 Cerebrospinal P-tau181p levels; LIHC cis rs9660992 0.573 rs12140703 chr1:205182865 G/C cg21545522 chr1:205238299 TMCC2 0.37 7.08 0.36 8.15e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2274273 0.870 rs10144345 chr14:55847737 T/C cg01864836 chr14:55583639 NA -0.41 -7.61 -0.38 2.63e-13 Protein biomarker; LIHC cis rs6582630 0.599 rs11181807 chr12:38403763 G/A cg26384229 chr12:38710491 ALG10B -0.47 -6.15 -0.32 2.17e-9 Drug-induced liver injury (flucloxacillin); LIHC trans rs561341 1.000 rs2470243 chr17:30290955 C/T cg20587970 chr11:113659929 NA -1.46 -11.99 -0.54 6.92e-28 Hip circumference adjusted for BMI; LIHC cis rs7072216 0.726 rs4474372 chr10:100164571 C/T cg26618903 chr10:100175079 PYROXD2 -0.39 -6.37 -0.33 6.27e-10 Metabolite levels; LIHC cis rs6429082 0.818 rs704714 chr1:235632094 T/C cg26050004 chr1:235667680 B3GALNT2 0.49 7.48 0.38 6.27e-13 Adiposity; LIHC cis rs9916302 0.706 rs9906612 chr17:37547631 A/C cg07936489 chr17:37558343 FBXL20 0.86 12.47 0.56 1.13e-29 Glomerular filtration rate (creatinine); LIHC cis rs763121 0.853 rs5757200 chr22:39043491 T/G cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs6912958 0.703 rs6903219 chr6:88096498 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.57 10.52 0.49 1.36e-22 Monocyte percentage of white cells; LIHC trans rs877282 1.000 rs11253361 chr10:770387 T/C cg22713356 chr15:30763199 NA 1.25 11.14 0.52 8.51e-25 Uric acid levels; LIHC cis rs208520 0.690 rs6932475 chr6:66863155 G/A cg07460842 chr6:66804631 NA -0.78 -8.41 -0.41 1.15e-15 Exhaled nitric oxide output; LIHC trans rs1814175 0.615 rs7113020 chr11:49746540 C/T cg15704280 chr7:45808275 SEPT13 -0.97 -20.89 -0.75 4.61e-63 Height; LIHC cis rs4862750 0.914 rs9995391 chr4:187873749 A/T cg03452623 chr4:187889614 NA 0.31 7.69 0.38 1.56e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs3741404 0.868 rs595880 chr11:64006466 T/G cg04317338 chr11:64019027 PLCB3 -0.55 -7.44 -0.37 8.16e-13 Platelet count; LIHC cis rs4819052 0.851 rs28622522 chr21:46676599 G/T cg11663144 chr21:46675770 NA -0.31 -5.72 -0.3 2.32e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1451375 0.617 rs10267323 chr7:50591424 A/G cg14593290 chr7:50529359 DDC 0.62 9.77 0.47 4.77e-20 Malaria; LIHC cis rs1403694 0.695 rs5029970 chr3:186434491 T/C cg12454167 chr3:186435060 KNG1 0.38 8.97 0.44 2.01e-17 Blood protein levels; LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg01339444 chr6:118972232 C6orf204 -0.6 -5.77 -0.3 1.75e-8 Diastolic blood pressure; LIHC cis rs7249142 0.597 rs759999 chr19:19281207 A/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.1 -0.31 2.8e-9 IgG glycosylation; LIHC cis rs7587476 0.601 rs17489363 chr2:215674341 A/G cg04004882 chr2:215674386 BARD1 -0.58 -8.18 -0.4 5.5e-15 Neuroblastoma; LIHC cis rs6450176 1.000 rs1445887 chr5:53299376 A/T ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs7927771 1.000 rs12421210 chr11:47779586 C/T cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.39e-18 Subjective well-being; LIHC cis rs2274273 0.774 rs17128440 chr14:55861912 C/T cg01864836 chr14:55583639 NA -0.34 -6.3 -0.32 9.41e-10 Protein biomarker; LIHC cis rs2153535 0.580 rs1932280 chr6:8473654 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs3814244 0.515 rs2906862 chr12:68399151 T/C cg15249341 chr12:68405565 NA 0.34 7.06 0.36 9.47e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs829883 0.664 rs829864 chr12:98850195 C/T cg25150519 chr12:98850993 NA 0.7 11.21 0.52 4.86e-25 Colorectal adenoma (advanced); LIHC cis rs6062302 0.522 rs6090476 chr20:62248001 G/A cg16989086 chr20:62203971 PRIC285 0.57 8.25 0.41 3.51e-15 Glioblastoma; LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg21724239 chr8:58056113 NA 0.56 7.39 0.37 1.1e-12 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.535 rs7671759 chr4:120248094 A/C cg09307838 chr4:120376055 NA 0.71 11.0 0.51 2.56e-24 Corneal astigmatism; LIHC cis rs12980942 0.872 rs12972949 chr19:41774935 G/T cg25627403 chr19:41769009 HNRNPUL1 0.59 6.9 0.35 2.48e-11 Coronary artery disease; LIHC cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1434579 0.897 rs2037904 chr19:44945091 A/G cg15540054 chr19:45004280 ZNF180 0.56 7.87 0.39 4.59e-14 Tuberculosis; LIHC cis rs7223966 0.655 rs9896476 chr17:61629692 C/G cg05941027 chr17:61774174 LIMD2 -0.31 -5.72 -0.3 2.31e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7914558 0.966 rs1971589 chr10:104744406 A/G cg15744005 chr10:104629667 AS3MT -0.42 -9.58 -0.46 2.02e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17760058 chr19:2321626 LSM7 0.41 6.08 0.31 3.13e-9 Longevity; LIHC cis rs1669338 1.000 rs1669338 chr3:3199635 A/C cg16797762 chr3:3221439 CRBN 0.79 8.11 0.4 8.9e-15 White matter integrity; LIHC trans rs6934970 1.000 rs12196496 chr6:113021779 T/A cg02620054 chr10:133946674 JAKMIP3 0.53 6.05 0.31 3.73e-9 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg00280220 chr17:61926910 NA 0.43 6.73 0.34 7.1e-11 Prudent dietary pattern; LIHC cis rs2749592 0.918 rs11011388 chr10:38155210 C/T cg25427524 chr10:38739819 LOC399744 0.56 9.51 0.46 3.56e-19 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2153535 0.580 rs6912193 chr6:8456306 T/G cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs2279817 0.775 rs35493100 chr1:17993120 C/T cg21791023 chr1:18019539 ARHGEF10L -0.68 -7.89 -0.39 4.25e-14 Neuroticism; LIHC cis rs111326718 1 rs111326718 chr10:104771211 A/AAAAAT cg15744005 chr10:104629667 AS3MT -0.39 -8.75 -0.43 1e-16 Reticulocyte count; LIHC cis rs2072499 0.833 rs2251847 chr1:156204047 G/A cg24450063 chr1:156163899 SLC25A44 0.71 12.28 0.55 5.83e-29 Testicular germ cell tumor; LIHC cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg10360323 chr17:41437877 NA 0.4 6.02 0.31 4.45e-9 Menopause (age at onset); LIHC cis rs2243480 1.000 rs67536397 chr7:65947917 G/A cg12463550 chr7:65579703 CRCP 0.59 5.93 0.31 7.32e-9 Diabetic kidney disease; LIHC cis rs3617 0.652 rs7630552 chr3:52891570 G/C cg11645453 chr3:52864694 ITIH4 -0.23 -6.15 -0.32 2.16e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs908922 0.887 rs4845783 chr1:152492559 G/A cg20991723 chr1:152506922 NA 0.4 6.14 0.32 2.29e-9 Hair morphology; LIHC cis rs1113500 0.787 rs11185266 chr1:108642664 G/A cg06207961 chr1:108661230 NA 0.31 6.01 0.31 4.74e-9 Growth-regulated protein alpha levels; LIHC cis rs7071206 0.898 rs28706743 chr10:79394329 T/G cg07817648 chr10:79422355 NA -0.35 -7.28 -0.37 2.33e-12 Bone mineral density; LIHC cis rs6952808 0.792 rs4721184 chr7:1950784 T/C cg21782813 chr7:2030301 MAD1L1 0.49 8.17 0.4 5.97e-15 Bipolar disorder and schizophrenia; LIHC cis rs2180341 1.000 rs4895822 chr6:127642703 T/C cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs66569888 0.789 rs1317569 chr2:106735490 C/A cg00318621 chr2:106887213 NA -0.58 -5.96 -0.31 6.17e-9 Facial morphology (factor 23); LIHC cis rs79387448 0.655 rs79091585 chr2:102917243 C/T cg09003973 chr2:102972529 NA 1.22 9.91 0.47 1.63e-20 Gut microbiota (bacterial taxa); LIHC trans rs61931739 0.534 rs11053016 chr12:34104372 C/T cg26384229 chr12:38710491 ALG10B 0.53 7.29 0.37 2.14e-12 Morning vs. evening chronotype; LIHC cis rs4555082 0.834 rs2735825 chr14:105710900 G/A cg13114125 chr14:105738426 BRF1 -0.82 -10.64 -0.5 4.93e-23 Mean platelet volume;Platelet distribution width; LIHC cis rs4407350 0.967 rs4522715 chr22:44922347 G/A cg11695653 chr22:44894386 LDOC1L -0.37 -6.08 -0.31 3.15e-9 Intelligence (multi-trait analysis); LIHC cis rs10857712 0.904 rs7918164 chr10:135223323 G/A cg01444801 chr10:135216882 MTG1 -0.66 -9.88 -0.47 2.12e-20 Systemic lupus erythematosus; LIHC cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg21782813 chr7:2030301 MAD1L1 0.47 8.0 0.4 2e-14 Bipolar disorder and schizophrenia; LIHC cis rs2979489 0.591 rs62508371 chr8:30422060 C/T cg26383811 chr8:30366931 RBPMS -0.64 -9.92 -0.47 1.54e-20 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs6582630 0.519 rs11495724 chr12:38337507 T/C cg26384229 chr12:38710491 ALG10B 0.6 8.33 0.41 1.93e-15 Drug-induced liver injury (flucloxacillin); LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg13815390 chr20:61568896 DIDO1;C20orf11 -0.42 -6.09 -0.31 3.1e-9 Triglycerides; LIHC cis rs7224685 1.000 rs1377807 chr17:4045440 C/G cg11204139 chr17:3907470 NA 0.69 8.71 0.43 1.32e-16 Type 2 diabetes; LIHC cis rs11871801 1.000 rs72823064 chr17:40569974 T/C cg14558262 chr17:40713999 COASY 0.46 5.74 0.3 2.04e-8 Crohn's disease; LIHC cis rs7829975 0.564 rs2921060 chr8:8317817 G/T cg08975724 chr8:8085496 FLJ10661 -0.52 -8.12 -0.4 8.58e-15 Mood instability; LIHC trans rs11760633 0.607 rs11761457 chr7:1829228 C/T cg00395210 chr12:48592465 NA 0.34 6.06 0.31 3.53e-9 Coronary artery disease; LIHC cis rs10489202 0.608 rs35059151 chr1:168079393 C/A cg24449463 chr1:168025552 DCAF6 -0.53 -8.07 -0.4 1.17e-14 Schizophrenia; LIHC cis rs1577917 1.000 rs13217384 chr6:86720000 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -10.99 -0.51 2.79e-24 Response to antipsychotic treatment; LIHC cis rs2204008 0.689 rs1581357 chr12:38391479 C/G cg26384229 chr12:38710491 ALG10B 0.61 8.0 0.4 1.99e-14 Bladder cancer; LIHC cis rs45544231 0.569 rs9923558 chr16:52548183 A/T cg09051775 chr16:52580266 TOX3 -0.32 -5.77 -0.3 1.81e-8 Restless legs syndrome; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10491242 chr19:50366052 PNKP 0.43 6.29 0.32 9.62e-10 Pancreatic cancer; LIHC cis rs17106184 0.688 rs10788930 chr1:51118253 C/T cg07174182 chr1:51127561 FAF1 -0.46 -6.11 -0.31 2.73e-9 Type 2 diabetes; LIHC cis rs1046896 0.594 rs9914570 chr17:80783721 C/T cg02711726 chr17:80685570 FN3KRP -0.44 -7.99 -0.4 2.13e-14 Glycated hemoglobin levels; LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs12887734 0.546 rs12885509 chr14:104273325 T/C cg24130564 chr14:104152367 KLC1 -0.43 -7.05 -0.36 1.02e-11 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs920590 0.758 rs1826420 chr8:19664878 G/T cg17834443 chr8:19674713 INTS10 0.48 7.19 0.36 4.13e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs965469 0.779 rs2236115 chr20:3296279 G/A cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg26818010 chr10:134567672 INPP5A -0.79 -9.6 -0.46 1.81e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11958404 0.932 rs72816549 chr5:157417957 G/A cg05962755 chr5:157440814 NA 0.96 10.52 0.49 1.28e-22 IgG glycosylation; LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg11060661 chr22:24314208 DDT;DDTL 0.55 8.71 0.43 1.29e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs57920188 0.584 rs12080516 chr1:4089613 C/T cg20703997 chr1:4087676 NA 0.5 6.77 0.34 5.59e-11 Interleukin-17 levels; LIHC cis rs6762 0.748 rs28551040 chr11:840740 G/A cg07691484 chr11:842764 TSPAN4;POLR2L -0.75 -9.31 -0.45 1.61e-18 Mean platelet volume; LIHC cis rs7224737 1.000 rs12603330 chr17:40290589 T/A cg02450064 chr17:40260053 DHX58 -0.3 -6.14 -0.32 2.24e-9 Fibrinogen levels; LIHC cis rs17685 0.725 rs4728548 chr7:75654632 A/T cg01364799 chr7:75623366 TMEM120A 0.43 6.48 0.33 3.22e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7149242 1.000 rs7149242 chr14:101159416 G/T cg11726507 chr14:101155519 NA 0.27 6.01 0.31 4.81e-9 Platelet count; LIHC cis rs3796352 1.000 rs13092352 chr3:52969697 C/T cg07884673 chr3:53033167 SFMBT1 0.88 6.5 0.33 2.77e-10 Immune reponse to smallpox (secreted IL-2); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06530028 chr7:143078179 ZYX 0.46 6.44 0.33 3.93e-10 Pancreatic cancer; LIHC cis rs12586317 0.547 rs10142667 chr14:35445090 A/G cg05294307 chr14:35346193 BAZ1A -0.46 -6.84 -0.35 3.69e-11 Psoriasis; LIHC cis rs727505 1.000 rs55964341 chr7:124517280 A/G cg23710748 chr7:124431027 NA -0.32 -5.78 -0.3 1.66e-8 Lewy body disease; LIHC cis rs2286885 1.000 rs741022 chr9:129252113 C/G cg15282417 chr9:129245246 FAM125B 0.39 6.22 0.32 1.46e-9 Intraocular pressure; LIHC cis rs11608355 0.545 rs6606721 chr12:109891999 G/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs7100689 0.646 rs1934696 chr10:82124966 T/C cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs6061231 0.546 rs482220 chr20:60927482 G/A cg03945807 chr20:60948434 NA -0.39 -6.89 -0.35 2.67e-11 Colorectal cancer; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg07677032 chr17:61819896 STRADA 0.43 6.31 0.32 8.5e-10 Prudent dietary pattern; LIHC cis rs7116495 0.609 rs1791456 chr11:71594888 G/C cg26138937 chr11:71823887 C11orf51 1.19 9.52 0.46 3.37e-19 Severe influenza A (H1N1) infection; LIHC cis rs6748734 0.901 rs6720357 chr2:241830296 A/C cg08694578 chr2:241835147 C2orf54 -0.51 -7.16 -0.36 4.88e-12 Urinary metabolites; LIHC cis rs6121246 0.909 rs6119720 chr20:30347568 T/G cg13852791 chr20:30311386 BCL2L1 0.95 9.7 0.46 8.02e-20 Mean corpuscular hemoglobin; LIHC cis rs6565180 0.926 rs4788409 chr16:30393771 G/A cg17640201 chr16:30407289 ZNF48 0.78 12.91 0.57 2.53e-31 Tonsillectomy; LIHC cis rs589448 0.902 rs315138 chr12:69764850 A/T cg14784868 chr12:69753453 YEATS4 0.98 22.84 0.78 9.05e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs6598955 0.724 rs7526545 chr1:26569990 C/A cg00852783 chr1:26633632 UBXN11 0.49 8.27 0.41 3.05e-15 Obesity-related traits; LIHC cis rs34375054 0.752 rs12582808 chr12:125661459 G/T cg25124228 chr12:125621409 AACS -0.4 -6.57 -0.33 1.89e-10 Post bronchodilator FEV1/FVC ratio; LIHC trans rs12476592 0.530 rs77804166 chr2:64160237 G/A cg06077443 chr18:10457385 APCDD1 0.36 6.09 0.31 3.07e-9 Childhood ear infection; LIHC cis rs4407350 0.870 rs2213373 chr22:44911669 C/T cg26276947 chr22:44892394 LDOC1L 0.34 6.56 0.33 1.99e-10 Intelligence (multi-trait analysis); LIHC cis rs1559088 0.847 rs10416218 chr19:33599127 T/C cg27124370 chr19:33622961 WDR88 0.5 7.66 0.38 1.93e-13 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs72781680 1.000 rs72788278 chr2:24095285 A/C cg08917208 chr2:24149416 ATAD2B 0.86 8.16 0.4 6.31e-15 Lymphocyte counts; LIHC cis rs912057 0.609 rs1294431 chr6:6745003 G/C cg06612196 chr6:6737390 NA 0.51 9.53 0.46 3.06e-19 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs7618915 1.000 rs3844291 chr3:52341215 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.4 6.27 0.32 1.06e-9 Bipolar disorder; LIHC cis rs9549367 0.713 rs4907599 chr13:113861441 C/T cg00898013 chr13:113819073 PROZ 0.36 6.35 0.32 6.76e-10 Platelet distribution width; LIHC cis rs17685 0.884 rs6978677 chr7:75636240 C/T cg01364799 chr7:75623366 TMEM120A -0.45 -6.81 -0.35 4.5e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6882046 0.513 rs254779 chr5:88019629 T/C cg22951263 chr5:87985283 NA -0.39 -6.72 -0.34 7.43e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs17401966 0.838 rs4846209 chr1:10322054 G/A cg19773385 chr1:10388646 KIF1B -0.4 -7.29 -0.37 2.18e-12 Hepatocellular carcinoma; LIHC cis rs2576037 0.558 rs7244778 chr18:44541915 T/C cg19077165 chr18:44547161 KATNAL2 -0.44 -6.71 -0.34 7.98e-11 Personality dimensions; LIHC cis rs904251 0.523 rs2797796 chr6:37480886 T/C cg08126542 chr6:37504118 NA -0.37 -6.3 -0.32 9.03e-10 Cognitive performance; LIHC cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC cis rs769267 0.930 rs892021 chr19:19613480 T/C cg03709012 chr19:19516395 GATAD2A 1.01 18.36 0.7 6.84e-53 Tonsillectomy; LIHC cis rs7618501 0.633 rs2624843 chr3:49997963 G/A cg24110177 chr3:50126178 RBM5 -0.48 -7.73 -0.39 1.2e-13 Intelligence (multi-trait analysis); LIHC cis rs61990749 0.597 rs28534379 chr14:78172140 G/A cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.8 0.39 7.44e-14 Fibroblast growth factor basic levels; LIHC trans rs3743102 0.591 rs12148608 chr15:83382102 A/G cg01542190 chr22:50604728 NA 0.55 7.43 0.37 8.98e-13 Colorectal adenoma (advanced); LIHC cis rs12701220 0.504 rs12702092 chr7:1145868 G/A cg04498913 chr7:1135747 C7orf50 0.39 5.84 0.3 1.22e-8 Bronchopulmonary dysplasia; LIHC cis rs78545713 1.000 rs3734534 chr6:26240649 A/G cg16070018 chr6:26224392 HIST1H3E -0.59 -6.5 -0.33 2.9e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs561341 0.941 rs2428341 chr17:30317295 C/T cg13647721 chr17:30228624 UTP6 0.69 6.72 0.34 7.39e-11 Hip circumference adjusted for BMI; LIHC cis rs74417235 0.673 rs6873342 chr5:154051835 A/G cg08893839 chr5:154027129 NA -0.51 -7.1 -0.36 7.49e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs2153535 0.541 rs945304 chr6:8442892 A/G cg07606381 chr6:8435919 SLC35B3 0.78 11.51 0.53 4.02e-26 Motion sickness; LIHC cis rs9649465 1.000 rs10215466 chr7:123326044 G/T cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.02e-15 Migraine; LIHC cis rs10751667 0.666 rs7395182 chr11:927553 A/C cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs965469 1.000 rs2236108 chr20:3286331 A/C cg25506879 chr20:3388711 C20orf194 -0.55 -6.74 -0.34 6.9e-11 IFN-related cytopenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10285711 chr2:135762012 YSK4 0.48 6.17 0.32 1.88e-9 Lung function (FEV1/FVC); LIHC cis rs9914988 0.943 rs9908881 chr17:27100924 T/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7078219 0.505 rs7908704 chr10:101293318 G/A cg06854084 chr10:101292507 NKX2-3 -0.33 -6.09 -0.31 3.12e-9 Dental caries; LIHC trans rs783540 0.967 rs1259183 chr15:83279433 C/T cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.66 -0.34 1.1e-10 Schizophrenia; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg27586682 chr1:26437624 PDIK1L 0.45 6.19 0.32 1.76e-9 Alopecia areata; LIHC cis rs12474201 0.928 rs12998753 chr2:46938385 A/G cg06386533 chr2:46925753 SOCS5 0.75 8.18 0.4 5.53e-15 Height; LIHC cis rs17106184 1.000 rs11205777 chr1:51286954 T/A cg07174182 chr1:51127561 FAF1 -0.59 -6.78 -0.34 5.2e-11 Type 2 diabetes; LIHC cis rs5770917 1.000 rs762677 chr22:51017713 G/A cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.44 -6.42 -0.33 4.54e-10 Narcolepsy; LIHC cis rs4555082 0.718 rs28513571 chr14:105709592 C/A cg13114125 chr14:105738426 BRF1 -0.72 -9.65 -0.46 1.2e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs6831352 0.918 rs2851246 chr4:100046104 A/G cg12011299 chr4:100065546 ADH4 0.59 10.15 0.48 2.53e-21 Alcohol dependence; LIHC cis rs919433 0.929 rs10931779 chr2:198166825 A/G cg03934865 chr2:198174659 NA -0.6 -9.62 -0.46 1.5700000000000001e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg21448741 chr8:58168803 NA 0.35 6.24 0.32 1.29e-9 Developmental language disorder (linguistic errors); LIHC cis rs6582630 0.519 rs11520262 chr12:38333051 A/G cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.57e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs769267 0.965 rs735273 chr19:19385411 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg03874509 chr1:107600012 PRMT6 -0.7 -10.98 -0.51 3.17e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3770081 1.000 rs12612513 chr2:86301225 G/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.87 -8.58 -0.42 3.25e-16 Facial emotion recognition (sad faces); LIHC trans rs4650994 1.000 rs17276513 chr1:178520604 A/T cg05059571 chr16:84539110 KIAA1609 0.37 6.39 0.33 5.51e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg02290350 chr8:58132656 NA 0.4 8.5 0.42 6.16e-16 Developmental language disorder (linguistic errors); LIHC cis rs7296418 0.961 rs1790122 chr12:123606739 G/A cg05973401 chr12:123451056 ABCB9 0.49 7.48 0.38 6.16e-13 Platelet count; LIHC cis rs11971779 1.000 rs11971779 chr7:139040258 A/G cg07862535 chr7:139043722 LUC7L2 -0.7 -10.38 -0.49 4.06e-22 Diisocyanate-induced asthma; LIHC cis rs1034435 0.755 rs5767173 chr22:48892473 T/C cg05992904 chr22:48892994 FAM19A5 -0.52 -10.94 -0.51 4.43e-24 Late-onset Alzheimer's disease; LIHC trans rs6467710 0.744 rs834093 chr7:137210014 T/C cg04467748 chr15:79760772 KIAA1024 0.44 6.42 0.33 4.52e-10 AIDS progression; LIHC cis rs11148252 0.904 rs9568732 chr13:52993412 A/G cg00495681 chr13:53174319 NA -0.42 -7.12 -0.36 6.32e-12 Lewy body disease; LIHC cis rs9303280 0.901 rs2952140 chr17:37928059 C/T cg11212589 chr17:38028394 ZPBP2 -0.33 -6.91 -0.35 2.31e-11 Self-reported allergy; LIHC cis rs12594515 0.967 rs11070465 chr15:45984899 A/G cg19682013 chr15:45996608 NA 0.4 7.12 0.36 6.25e-12 Waist circumference;Weight; LIHC cis rs7474896 0.561 rs2474603 chr10:38445682 C/T cg25427524 chr10:38739819 LOC399744 -0.5 -6.7 -0.34 8.84e-11 Obesity (extreme); LIHC cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg07424592 chr7:64974309 NA 0.79 9.05 0.44 1.09e-17 Diabetic kidney disease; LIHC cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.85 -0.39 5.42e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs9916302 0.904 rs3744348 chr17:37417575 C/G cg00129232 chr17:37814104 STARD3 -0.39 -6.24 -0.32 1.27e-9 Glomerular filtration rate (creatinine); LIHC cis rs13631 0.928 rs9411308 chr9:140000115 C/T cg14289826 chr9:140003911 NA 0.51 8.89 0.43 3.63e-17 Cerebrospinal fluid biomarker levels; LIHC cis rs67981189 0.593 rs7154437 chr14:71441385 A/G cg15816911 chr14:71606274 NA 0.42 6.65 0.34 1.14e-10 Schizophrenia; LIHC cis rs4474465 1.000 rs10899505 chr11:78165343 T/C cg02023728 chr11:77925099 USP35 0.32 5.76 0.3 1.89e-8 Alzheimer's disease (survival time); LIHC cis rs10792665 0.575 rs1939136 chr11:82558046 A/T cg24227371 chr11:82718527 RAB30 -0.25 -5.99 -0.31 5.19e-9 Obesity-related traits; LIHC trans rs1005277 0.540 rs289638 chr10:37923731 G/A cg23533926 chr12:111358616 MYL2 -0.33 -6.4 -0.33 4.98e-10 Extrinsic epigenetic age acceleration; LIHC cis rs3008870 0.959 rs1886686 chr1:67390468 C/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.46 0.66 3.08e-45 Lymphocyte percentage of white cells; LIHC cis rs17253792 0.822 rs74053651 chr14:56125366 C/T cg01858014 chr14:56050164 KTN1 -0.73 -8.35 -0.41 1.74e-15 Putamen volume; LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.19 0.55 1.26e-28 Height; LIHC cis rs644799 0.965 rs1944080 chr11:95503636 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.15 0.68 5.4e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4423214 0.879 rs1792284 chr11:71134966 A/G cg05163923 chr11:71159392 DHCR7 0.63 8.56 0.42 3.87e-16 Vitamin D levels; LIHC cis rs3761847 0.622 rs10435888 chr9:123819603 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.42 5.85 0.3 1.17e-8 Rheumatoid arthritis; LIHC cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg12310025 chr6:25882481 NA -0.47 -7.17 -0.36 4.57e-12 Height; LIHC cis rs1862618 0.525 rs832403 chr5:56265992 G/T cg12311346 chr5:56204834 C5orf35 0.61 7.74 0.39 1.11e-13 Initial pursuit acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16490470 chr1:208390388 PLXNA2 0.41 6.18 0.32 1.82e-9 Longevity; LIHC cis rs12824058 0.798 rs4759652 chr12:130808771 C/T cg24838063 chr12:130822603 PIWIL1 0.67 9.85 0.47 2.54e-20 Menopause (age at onset); LIHC cis rs7945705 0.935 rs10769971 chr11:8925276 C/T cg12365402 chr11:9010492 NRIP3 0.31 7.91 0.39 3.7e-14 Hemoglobin concentration; LIHC cis rs7129220 0.588 rs16907481 chr11:10144108 A/T cg01453529 chr11:10209919 SBF2 -0.37 -6.68 -0.34 9.53e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg00656387 chr3:40428638 ENTPD3 0.42 7.03 0.36 1.15e-11 Renal cell carcinoma; LIHC cis rs801193 1.000 rs10234018 chr7:66146284 A/T cg18876405 chr7:65276391 NA -0.43 -7.39 -0.37 1.16e-12 Aortic root size; LIHC cis rs6952808 0.609 rs12699453 chr7:1953056 C/T cg04267008 chr7:1944627 MAD1L1 -0.66 -10.55 -0.5 1.05e-22 Bipolar disorder and schizophrenia; LIHC cis rs3960554 0.569 rs10954750 chr7:75664921 C/G cg04610667 chr7:75704037 NA 0.35 6.0 0.31 4.91e-9 Eotaxin levels; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg24693881 chr1:107596107 NA -0.49 -8.0 -0.4 2e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs875971 0.502 rs11769702 chr7:65720516 A/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.22 0.36 3.4e-12 Aortic root size; LIHC cis rs7572733 0.534 rs770662 chr2:198729283 T/C cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs2760061 0.626 rs596208 chr1:228117982 G/C cg02753203 chr1:228287806 NA -0.5 -7.94 -0.39 2.91e-14 Diastolic blood pressure; LIHC cis rs10508774 1.000 rs12416352 chr10:32919749 T/G cg01819863 chr10:32635814 EPC1 0.63 5.88 0.3 9.9e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs797680 0.796 rs797661 chr1:93687091 G/T cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.88 0.3 1e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs7927592 0.913 rs7118897 chr11:68360680 G/A cg01657329 chr11:68192670 LRP5 -0.47 -6.18 -0.32 1.82e-9 Total body bone mineral density; LIHC trans rs2243480 0.803 rs423187 chr7:65509499 G/C cg10756647 chr7:56101905 PSPH 1.08 13.46 0.59 2e-33 Diabetic kidney disease; LIHC cis rs11958404 0.932 rs72816585 chr5:157433901 A/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07368265 chr1:219375142 LYPLAL1 -0.35 -6.08 -0.31 3.21e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4853012 0.838 rs60964317 chr2:74343423 A/T cg20011983 chr2:74347215 NA -0.39 -5.78 -0.3 1.68e-8 Gestational age at birth (maternal effect); LIHC cis rs9311474 0.607 rs34005367 chr3:52558904 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.19 0.45 3.83e-18 Electroencephalogram traits; LIHC cis rs7592578 0.723 rs4371384 chr2:191430741 A/G cg27211696 chr2:191398769 TMEM194B 0.6 7.74 0.39 1.12e-13 Diastolic blood pressure; LIHC trans rs2727020 0.701 rs7949044 chr11:49597334 C/T cg03929089 chr4:120376271 NA -0.73 -11.29 -0.52 2.5e-25 Coronary artery disease; LIHC cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg21782813 chr7:2030301 MAD1L1 0.51 9.1 0.44 7.83e-18 Bipolar disorder and schizophrenia; LIHC cis rs11252926 0.507 rs4881199 chr10:428090 C/G cg18196295 chr10:418757 DIP2C 0.39 5.76 0.3 1.88e-8 Psychosis in Alzheimer's disease; LIHC cis rs6840360 1.000 rs2278304 chr4:152593409 C/T cg22705602 chr4:152727874 NA 0.3 6.24 0.32 1.28e-9 Intelligence (multi-trait analysis); LIHC cis rs2439831 1.000 rs2467743 chr15:43750346 T/A cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.96 0.44 2.2e-17 Lung cancer in ever smokers; LIHC cis rs876084 0.505 rs9969584 chr8:121104786 G/A cg06265175 chr8:121136014 COL14A1 0.49 7.99 0.4 2.09e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14729855 chr6:34204698 HMGA1 0.46 6.44 0.33 3.96e-10 Lung function (FEV1/FVC); LIHC cis rs1580019 0.922 rs59938271 chr7:32484844 T/C cg07520158 chr7:32535189 LSM5;AVL9 0.49 6.6 0.34 1.53e-10 Cognitive ability; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.84 0.54 2.44e-27 Prudent dietary pattern; LIHC cis rs7224685 0.501 rs781848 chr17:3958105 A/C cg11204139 chr17:3907470 NA 0.64 10.85 0.51 9.42e-24 Type 2 diabetes; LIHC cis rs7903847 0.620 rs11189165 chr10:99123457 A/G cg06359132 chr10:99160096 RRP12 -0.4 -6.04 -0.31 4.02e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs959260 1.000 rs2033609 chr17:73367021 C/T cg20590849 chr17:73267439 MIF4GD -0.54 -5.83 -0.3 1.25e-8 Systemic lupus erythematosus; LIHC cis rs7246657 0.941 rs7259618 chr19:37750719 G/A cg23950597 chr19:37808831 NA -0.51 -6.53 -0.33 2.33e-10 Coronary artery calcification; LIHC cis rs4660306 0.614 rs781057 chr1:45936017 C/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.63 6.8 0.35 4.73e-11 Homocysteine levels; LIHC cis rs1577917 0.739 rs9344532 chr6:86234070 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 7.97 0.4 2.4e-14 Response to antipsychotic treatment; LIHC cis rs9326248 0.954 rs521171 chr11:117064693 C/G cg10130564 chr11:117069849 TAGLN 0.37 6.32 0.32 8.3e-10 Blood protein levels; LIHC cis rs3008870 0.755 rs1024229 chr1:67512903 G/T cg02640540 chr1:67518911 SLC35D1 0.67 13.13 0.58 3.52e-32 Lymphocyte percentage of white cells; LIHC cis rs9549328 0.756 rs2993291 chr13:113653846 C/T cg00071026 chr13:113650936 MCF2L -0.37 -5.72 -0.3 2.28e-8 Systolic blood pressure; LIHC cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg20295408 chr7:1910781 MAD1L1 -0.48 -6.63 -0.34 1.28e-10 Bipolar disorder and schizophrenia; LIHC cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg18357526 chr6:26021779 HIST1H4A 1.04 15.0 0.63 1.95e-39 Intelligence (multi-trait analysis); LIHC cis rs870825 0.616 rs1401360 chr4:185643571 T/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs6598955 0.640 rs4233460 chr1:26633387 A/G cg04990556 chr1:26633338 UBXN11 -0.61 -9.83 -0.47 3.08e-20 Obesity-related traits; LIHC cis rs12701220 0.901 rs12701713 chr7:1090505 G/A cg26769984 chr7:1090371 C7orf50 0.6 7.74 0.39 1.15e-13 Bronchopulmonary dysplasia; LIHC cis rs9467773 0.565 rs6925047 chr6:26521435 C/G cg09904177 chr6:26538194 HMGN4 0.53 8.8 0.43 7.1e-17 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.913 rs12283755 chr11:68371658 A/G cg16797656 chr11:68205561 LRP5 0.49 7.79 0.39 7.88e-14 Total body bone mineral density; LIHC cis rs67460515 0.531 rs1585483 chr3:160843111 G/A cg03342759 chr3:160939853 NMD3 -0.61 -8.87 -0.43 4.17e-17 Parkinson's disease; LIHC cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg24675658 chr1:53192096 ZYG11B 0.82 13.49 0.59 1.54e-33 Monocyte count; LIHC cis rs10256972 0.967 rs7799110 chr7:1039065 A/G cg16145915 chr7:1198662 ZFAND2A -0.29 -7.26 -0.37 2.62e-12 Longevity;Endometriosis; LIHC cis rs11212260 0.655 rs11212215 chr11:107287405 G/A cg25435332 chr11:107328525 CWF19L2 0.8 8.18 0.4 5.7e-15 IgG glycosylation; LIHC cis rs7208859 0.524 rs59913838 chr17:29101563 A/T cg14067834 chr17:29058358 SUZ12P 0.72 7.12 0.36 6.39e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17666538 0.535 rs896522 chr8:616991 A/G cg23958373 chr8:599963 NA 0.77 5.9 0.3 8.85e-9 IgG glycosylation; LIHC cis rs7107174 1.000 rs2511190 chr11:77988310 T/C cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs11098499 0.863 rs3736115 chr4:120488703 A/G cg09307838 chr4:120376055 NA -0.78 -12.18 -0.55 1.4e-28 Corneal astigmatism; LIHC cis rs9858542 0.953 rs11710037 chr3:49675334 C/G cg03060546 chr3:49711283 APEH -0.6 -7.97 -0.4 2.35e-14 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01585758 chr2:203102753 SUMO1 0.45 6.53 0.33 2.32e-10 Pancreatic cancer; LIHC cis rs2072499 0.865 rs2758608 chr1:156202860 A/T cg25208724 chr1:156163844 SLC25A44 0.57 9.46 0.46 5.2e-19 Testicular germ cell tumor; LIHC cis rs4908768 0.539 rs11121204 chr1:8654305 A/G cg20416874 chr1:8611966 RERE 0.62 11.1 0.51 1.15e-24 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1577917 1.000 rs1857964 chr6:86635994 A/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.21 -0.36 3.63e-12 Response to antipsychotic treatment; LIHC cis rs7772486 0.790 rs2253768 chr6:146199922 A/G cg23711669 chr6:146136114 FBXO30 0.66 11.84 0.54 2.39e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs6701037 1.000 rs7514749 chr1:175122123 A/G cg17845761 chr1:175162550 KIAA0040 -0.37 -6.14 -0.31 2.35e-9 Alcohol dependence; LIHC cis rs4713118 0.869 rs6914924 chr6:27711530 C/T cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs5769765 0.913 rs28670284 chr22:50221973 C/T cg02269571 chr22:50332266 NA -0.87 -10.37 -0.49 4.28e-22 Schizophrenia; LIHC cis rs17826219 0.568 rs11658027 chr17:29094882 A/G cg14067834 chr17:29058358 SUZ12P -0.73 -7.21 -0.36 3.53e-12 Body mass index; LIHC cis rs9303401 0.659 rs34818467 chr17:56643109 C/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.81 -12.18 -0.55 1.37e-28 Cognitive test performance; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg09263875 chr16:632152 PIGQ 0.59 10.89 0.51 6.49e-24 Height; LIHC cis rs796364 0.951 rs281776 chr2:200834282 T/G cg23649088 chr2:200775458 C2orf69 0.49 5.99 0.31 5.24e-9 Schizophrenia; LIHC cis rs17094222 0.504 rs12267029 chr10:102458677 C/A cg26540559 chr10:102447443 NA 0.4 7.71 0.38 1.4e-13 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1580019 0.563 rs896137 chr7:32579345 G/T cg06627557 chr7:32535165 LSM5;AVL9 1.12 24.8 0.8 2.06e-78 Cognitive ability; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg02290350 chr8:58132656 NA 0.49 10.59 0.5 7.41e-23 Developmental language disorder (linguistic errors); LIHC cis rs881375 0.678 rs10760130 chr9:123701990 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.66 0.34 1.08e-10 Rheumatoid arthritis; LIHC cis rs881375 1.000 rs7037140 chr9:123656327 T/C cg14580859 chr9:123691850 NA 0.38 6.52 0.33 2.48e-10 Rheumatoid arthritis; LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs933688 0.536 rs332537 chr5:90794973 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 -0.71 -11.67 -0.53 1.06e-26 Smoking behavior; LIHC cis rs10791097 0.739 rs11222358 chr11:130730497 G/A cg14779329 chr11:130786720 SNX19 0.38 5.89 0.3 9.28e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1707322 0.686 rs2230659 chr1:46078884 C/T cg24296786 chr1:45957014 TESK2 0.43 6.25 0.32 1.2e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17253792 0.822 rs10083499 chr14:56066590 T/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs60871478 0.679 rs6962050 chr7:817201 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.52 5.82 0.3 1.37e-8 Cerebrospinal P-tau181p levels; LIHC cis rs9522267 0.535 rs4773392 chr13:112227358 A/G cg10483660 chr13:112241077 NA 0.22 6.03 0.31 4.27e-9 Hepatitis; LIHC cis rs80282103 0.618 rs57514701 chr10:1146169 G/A cg08668510 chr10:1095578 IDI1 0.62 6.07 0.31 3.45e-9 Glomerular filtration rate (creatinine); LIHC cis rs8180040 0.966 rs62260711 chr3:47564491 G/C cg27129171 chr3:47204927 SETD2 -0.54 -8.66 -0.42 1.86e-16 Colorectal cancer; LIHC cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg10774155 chr7:65338427 VKORC1L1 0.47 6.97 0.35 1.6e-11 Calcium levels; LIHC cis rs11583043 0.874 rs6577219 chr1:101415707 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.13 0.31 2.41e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.62 -0.5 6.07e-23 Platelet count; LIHC cis rs875971 0.755 rs76288834 chr7:66069802 G/A cg18252515 chr7:66147081 NA 0.45 6.63 0.34 1.32e-10 Aortic root size; LIHC cis rs8072100 0.745 rs7214410 chr17:45422628 A/G cg08085267 chr17:45401833 C17orf57 -0.59 -8.89 -0.43 3.58e-17 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6502050 0.805 rs6502061 chr17:80086158 C/T cg13198984 chr17:80129470 CCDC57 -0.33 -5.8 -0.3 1.54e-8 Life satisfaction; LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg16405210 chr4:1374714 KIAA1530 -0.52 -7.69 -0.38 1.53e-13 Obesity-related traits; LIHC cis rs963731 0.579 rs6739807 chr2:39287668 G/A cg04010122 chr2:39346883 SOS1 -0.59 -6.0 -0.31 5.04e-9 Corticobasal degeneration; LIHC cis rs11229555 0.645 rs11229429 chr11:58180872 G/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs3008870 1.000 rs1925412 chr1:67405057 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg05590025 chr7:65112418 INTS4L2 -0.62 -6.77 -0.34 5.68e-11 Diabetic kidney disease; LIHC cis rs11758351 0.866 rs75091077 chr6:26207546 A/C cg16070018 chr6:26224392 HIST1H3E 0.6 7.53 0.38 4.45e-13 Gout;Renal underexcretion gout; LIHC cis rs6570726 0.791 rs9322029 chr6:145906683 A/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.25 -0.32 1.25e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs208520 0.802 rs851600 chr6:66893754 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.32 -0.41 2.07e-15 Exhaled nitric oxide output; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26011197 chr5:175970570 NA -0.48 -6.36 -0.33 6.58e-10 Systolic blood pressure; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg09430954 chr19:46236890 NA 0.44 6.13 0.31 2.36e-9 Bilirubin levels; LIHC cis rs6831352 0.918 rs29001194 chr4:100054844 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs875971 0.862 rs4368860 chr7:65608482 C/G cg18876405 chr7:65276391 NA -0.38 -6.66 -0.34 1.08e-10 Aortic root size; LIHC cis rs2836950 0.545 rs8132143 chr21:40584258 A/T cg17971929 chr21:40555470 PSMG1 -0.39 -5.92 -0.3 7.86e-9 Menarche (age at onset); LIHC cis rs477895 0.838 rs1058735 chr11:64000410 C/G cg18225595 chr11:63971243 STIP1 0.66 8.19 0.4 5.24e-15 Mean platelet volume; LIHC trans rs7246657 0.943 rs13343502 chr19:37962292 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs4689388 0.679 rs1046316 chr4:6304087 A/G cg25554036 chr4:6271136 WFS1 0.42 5.76 0.3 1.83e-8 Type 2 diabetes and other traits;Type 2 diabetes; LIHC trans rs17685 0.672 rs1639618 chr7:75701987 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg18306943 chr3:40428807 ENTPD3 0.42 7.46 0.37 7.18e-13 Renal cell carcinoma; LIHC cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.712 rs869805 chr7:75688596 C/T cg16684958 chr7:75615977 POR 0.51 8.61 0.42 2.78e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs72781680 0.665 rs2953028 chr2:24068126 T/C cg08917208 chr2:24149416 ATAD2B 0.62 6.44 0.33 4.09e-10 Lymphocyte counts; LIHC trans rs4650994 0.935 rs4652306 chr1:178528206 T/C cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9457247 1.000 rs365189 chr6:167384545 G/A cg12798992 chr6:167411361 FGFR1OP 0.59 9.73 0.47 6.7e-20 Crohn's disease; LIHC cis rs2834188 1.000 rs1018741 chr21:34686345 G/A cg04842828 chr21:34696676 IFNAR1 0.44 5.98 0.31 5.73e-9 Narcolepsy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11786013 chr1:36622167 MAP7D1 0.43 6.04 0.31 4.11e-9 Lung function (FEV1/FVC); LIHC cis rs2153535 0.580 rs7742794 chr6:8459723 C/A cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs16828019 0.777 rs115916606 chr1:41642700 C/G cg03962019 chr1:41807865 NA 0.53 7.64 0.38 2.27e-13 Intelligence (multi-trait analysis); LIHC cis rs60871478 1.000 rs62432242 chr7:797715 G/A cg04727924 chr7:799746 HEATR2 -0.57 -8.49 -0.42 6.44e-16 Cerebrospinal P-tau181p levels; LIHC cis rs10193935 0.901 rs7594010 chr2:42534896 C/T cg27598129 chr2:42591480 NA -0.7 -10.65 -0.5 4.56e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs66573146 0.572 rs67252699 chr4:6946411 A/G cg00086871 chr4:6988644 TBC1D14 0.79 6.02 0.31 4.58e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs11083846 0.913 rs11668987 chr19:47227821 A/G cg08230695 chr19:47220755 PRKD2 -0.54 -5.81 -0.3 1.4e-8 Chronic lymphocytic leukemia; LIHC cis rs459571 0.920 rs460154 chr9:136909309 C/T cg13789015 chr9:136890014 NCRNA00094 0.43 8.14 0.4 7.32e-15 Platelet distribution width; LIHC cis rs699 0.556 rs2478525 chr1:230865350 C/G cg07502417 chr1:230849801 AGT 0.3 6.56 0.33 2.05e-10 Coronary artery disease; LIHC cis rs7119 0.643 rs12904384 chr15:77410878 T/G cg17802220 chr15:77601643 NA -0.36 -6.92 -0.35 2.3e-11 Type 2 diabetes; LIHC trans rs800082 0.690 rs2118001 chr3:144336609 T/C cg24215973 chr2:240111563 HDAC4 -0.55 -8.54 -0.42 4.36e-16 Smoking behavior; LIHC cis rs2303759 0.709 rs8102658 chr19:49828855 C/T cg22590775 chr19:49891494 CCDC155 0.48 7.62 0.38 2.51e-13 Multiple sclerosis; LIHC cis rs1448094 0.512 rs4488288 chr12:86245450 A/C cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC cis rs17345786 0.906 rs11708616 chr3:101231731 C/T cg12386194 chr3:101231763 SENP7 0.62 9.05 0.44 1.13e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs56145559 1 rs56145559 chr2:73623439 C/T cg20560298 chr2:73613845 ALMS1 -0.53 -5.97 -0.31 6.02e-9 Schizophrenia; LIHC cis rs7937682 0.824 rs510866 chr11:111484113 A/C cg09085632 chr11:111637200 PPP2R1B -0.9 -10.73 -0.5 2.4e-23 Primary sclerosing cholangitis; LIHC cis rs6500602 0.893 rs4786490 chr16:4491190 C/T cg08645402 chr16:4508243 NA -0.39 -7.51 -0.38 5.17e-13 Schizophrenia; LIHC cis rs10503871 0.690 rs7840384 chr8:30349914 A/G cg26383811 chr8:30366931 RBPMS 0.43 7.52 0.38 4.88e-13 Metabolite levels (X-11787); LIHC cis rs8062405 0.691 rs743590 chr16:28608230 G/A cg16576597 chr16:28551801 NUPR1 0.47 7.11 0.36 6.95e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs769267 0.896 rs2074298 chr19:19377716 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.63 9.72 0.47 7.23e-20 Tonsillectomy; LIHC trans rs783540 0.874 rs10468217 chr15:83248079 T/C cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.11 -0.31 2.7e-9 Schizophrenia; LIHC trans rs1973993 0.967 rs10489741 chr1:96942406 G/A cg10631902 chr5:14652156 NA 0.28 6.28 0.32 1.04e-9 Weight; LIHC cis rs8103278 1.000 rs1548029 chr19:46309203 A/C cg14061069 chr19:46274453 DMPK -0.54 -8.34 -0.41 1.91e-15 Coronary artery disease; LIHC cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg23978390 chr7:1156363 C7orf50 -0.57 -8.7 -0.43 1.45e-16 Longevity;Endometriosis; LIHC cis rs7208859 0.673 rs9895684 chr17:29242600 G/A cg13385521 chr17:29058706 SUZ12P 0.79 7.57 0.38 3.41e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10751667 0.961 rs7482484 chr11:927020 C/T cg10932868 chr11:921992 NA 0.35 6.57 0.33 1.93e-10 Alzheimer's disease (late onset); LIHC cis rs7937890 1.000 rs7937890 chr11:14396485 C/T cg02251663 chr11:14281053 SPON1 -0.43 -6.02 -0.31 4.49e-9 Mitochondrial DNA levels; LIHC cis rs3099143 1.000 rs2063542 chr15:77149498 A/G cg21673338 chr15:77095150 SCAPER -0.49 -7.71 -0.38 1.42e-13 Recalcitrant atopic dermatitis; LIHC cis rs7945705 0.967 rs10769973 chr11:8928615 C/G cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.06 0.36 9.23e-12 Hemoglobin concentration; LIHC cis rs12477438 0.798 rs6704766 chr2:99642818 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.84 -0.65 9.44e-43 Chronic sinus infection; LIHC cis rs7529073 0.815 rs1431982 chr1:214149061 T/G cg24083324 chr1:214162604 PROX1 -0.56 -8.55 -0.42 4.16e-16 Schizophrenia; LIHC trans rs2243480 1.000 rs34529418 chr7:65403209 A/G cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC trans rs1005277 0.579 rs1780130 chr10:38485378 T/A cg23533926 chr12:111358616 MYL2 -0.33 -6.26 -0.32 1.18e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1355223 0.583 rs2915238 chr11:34884405 C/A cg06937548 chr11:34938143 PDHX;APIP 0.41 5.83 0.3 1.27e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1023500 0.506 rs6002625 chr22:42517689 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.24 -0.32 1.29e-9 Schizophrenia; LIHC cis rs11098499 0.820 rs2389885 chr4:120533931 C/T cg09307838 chr4:120376055 NA 0.72 10.61 0.5 6.25e-23 Corneal astigmatism; LIHC cis rs67460515 0.500 rs9822435 chr3:160748068 A/T cg17135325 chr3:160939158 NMD3 0.5 6.66 0.34 1.12e-10 Parkinson's disease; LIHC cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg09177884 chr7:1199841 ZFAND2A -0.47 -6.96 -0.35 1.69e-11 Longevity;Endometriosis; LIHC cis rs7551222 0.646 rs7556371 chr1:204457336 A/G cg20240347 chr1:204465584 NA 0.31 6.61 0.34 1.52e-10 Schizophrenia; LIHC cis rs7224668 0.647 rs2271090 chr17:79246605 A/G cg08034816 chr17:79219380 SLC38A10 0.39 5.95 0.31 6.48e-9 IgG glycosylation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01910272 chr3:52489346 TNNC1;NISCH 0.46 6.59 0.34 1.63e-10 Lung function (FEV1/FVC); LIHC cis rs1538970 0.884 rs781232 chr1:45890399 C/T cg05343316 chr1:45956843 TESK2 -0.52 -7.57 -0.38 3.56e-13 Platelet count; LIHC cis rs55665837 1.000 rs11023215 chr11:14436970 C/T cg19336497 chr11:14380999 RRAS2 -0.45 -8.21 -0.41 4.65e-15 Vitamin D levels; LIHC cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg07424592 chr7:64974309 NA 0.82 9.56 0.46 2.49e-19 Diabetic kidney disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12790134 chr8:67578787 VCPIP1 -0.5 -6.07 -0.31 3.38e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9921222 0.521 rs62032884 chr16:363415 C/T cg08923669 chr16:420230 MRPL28 -0.47 -6.2 -0.32 1.64e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs2224391 1.000 rs9784870 chr6:5261359 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.41 -6.07 -0.31 3.45e-9 Height; LIHC cis rs12477438 0.520 rs11695379 chr2:99742161 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 13.94 0.6 2.8e-35 Chronic sinus infection; LIHC cis rs6582630 0.563 rs923281 chr12:38590241 G/A cg26384229 chr12:38710491 ALG10B -0.5 -6.95 -0.35 1.8e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC trans rs2243480 0.711 rs1626926 chr7:65435792 C/T cg10756647 chr7:56101905 PSPH 1.1 13.62 0.59 4.65e-34 Diabetic kidney disease; LIHC cis rs611744 0.967 rs650968 chr8:109211055 C/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02941728 chr11:60617807 CCDC86 0.42 6.59 0.34 1.68e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs801193 1.000 rs10234018 chr7:66146284 A/T cg11764359 chr7:65958608 NA -0.73 -10.92 -0.51 5.01e-24 Aortic root size; LIHC cis rs2842992 0.830 rs2842966 chr6:160141592 C/T cg11366901 chr6:160182831 ACAT2 0.92 15.61 0.65 7.13e-42 Age-related macular degeneration (geographic atrophy); LIHC cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg16822855 chr3:40428330 ENTPD3 -0.32 -5.79 -0.3 1.63e-8 Renal cell carcinoma; LIHC cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg00684032 chr4:1343700 KIAA1530 -0.35 -5.83 -0.3 1.3e-8 Obesity-related traits; LIHC cis rs7772486 0.686 rs1292336 chr6:145967818 T/C cg23711669 chr6:146136114 FBXO30 -0.63 -11.36 -0.52 1.37e-25 Lobe attachment (rater-scored or self-reported); LIHC trans rs2270927 0.510 rs2937748 chr5:75572032 T/G cg13563193 chr19:33072644 PDCD5 0.84 7.97 0.4 2.38e-14 Mean corpuscular volume; LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg11062466 chr8:58055876 NA 0.5 7.42 0.37 9.65e-13 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.526 rs2839297 chr21:47921839 A/G cg12379764 chr21:47803548 PCNT -0.52 -7.71 -0.38 1.43e-13 Testicular germ cell tumor; LIHC cis rs9916302 0.904 rs2338797 chr17:37548241 G/A cg00129232 chr17:37814104 STARD3 0.39 6.27 0.32 1.11e-9 Glomerular filtration rate (creatinine); LIHC cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg13877915 chr19:58951672 ZNF132 0.63 10.82 0.5 1.19e-23 Uric acid clearance; LIHC cis rs7731783 1 rs7731783 chr5:177060312 T/C cg10940203 chr5:177434438 FAM153C 0.4 7.39 0.37 1.14e-12 Methadone dose in opioid dependence; LIHC cis rs988712 0.662 rs11030100 chr11:27677586 G/T cg18117895 chr11:27722066 BDNF 0.5 6.81 0.35 4.4e-11 Obesity; LIHC cis rs713477 0.967 rs10150596 chr14:55916167 A/G cg13175173 chr14:55914753 NA 0.36 8.67 0.42 1.77e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg10802521 chr3:52805072 NEK4 -0.44 -7.22 -0.36 3.41e-12 Bipolar disorder; LIHC cis rs34779708 0.931 rs12261654 chr10:35322024 G/A cg03585969 chr10:35415529 CREM 0.84 12.66 0.56 2.25e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg05834845 chr3:195489306 MUC4 0.65 9.84 0.47 2.84e-20 Lung disease severity in cystic fibrosis; LIHC cis rs12477438 0.765 rs62156363 chr2:99693324 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.7 -0.5 3.03e-23 Chronic sinus infection; LIHC cis rs6696846 0.765 rs4394715 chr1:205108393 T/G cg21545522 chr1:205238299 TMCC2 0.32 6.15 0.32 2.13e-9 Red blood cell count; LIHC cis rs4319547 0.695 rs10773167 chr12:122934001 C/T cg23029597 chr12:123009494 RSRC2 -0.53 -7.4 -0.37 1.09e-12 Body mass index; LIHC cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.63 0.53 1.49e-26 Alzheimer's disease; LIHC trans rs1814175 0.715 rs1722007 chr11:49897319 T/C cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs5769765 0.819 rs9616377 chr22:50310880 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.85 -10.37 -0.49 4.36e-22 Schizophrenia; LIHC cis rs2279817 0.820 rs76593741 chr1:18010067 G/A cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.76 -0.39 9.68e-14 Neuroticism; LIHC cis rs1062746 0.738 rs2303764 chr16:87377455 C/G cg02258303 chr16:87377426 FBXO31 0.38 5.89 0.3 9.1e-9 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); LIHC cis rs12220238 1.000 rs9665468 chr10:75938838 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.76 7.4 0.37 1.06e-12 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs61990749 0.597 rs1477260 chr14:78256818 G/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.64 -0.38 2.22e-13 Fibroblast growth factor basic levels; LIHC trans rs2537594 0.936 rs1404418 chr7:17814085 A/T cg10150615 chr22:24372951 LOC391322 0.43 6.43 0.33 4.3e-10 Mean corpuscular hemoglobin; LIHC trans rs7193541 0.694 rs8061942 chr16:74691362 C/T cg23598604 chr1:99732472 LPPR4 -0.3 -6.41 -0.33 4.92e-10 Multiple myeloma; LIHC cis rs763121 0.853 rs5750649 chr22:39036769 T/C cg21395723 chr22:39101663 GTPBP1 0.41 7.0 0.35 1.35e-11 Menopause (age at onset); LIHC cis rs10779751 0.770 rs11121695 chr1:11229515 G/A cg08854313 chr1:11322531 MTOR -0.8 -10.56 -0.5 9.41e-23 Body mass index; LIHC cis rs13020137 1 rs13020137 chr2:130757304 A/G cg08790550 chr2:130955686 TUBA3E 0.45 7.53 0.38 4.61e-13 Schizophrenia; LIHC cis rs7249142 0.549 rs72997174 chr19:19294389 T/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.15 -0.32 2.17e-9 IgG glycosylation; LIHC cis rs1348850 0.574 rs11889488 chr2:178426793 A/G cg27490568 chr2:178487706 NA -1.0 -11.32 -0.52 1.98e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg17971929 chr21:40555470 PSMG1 -0.48 -7.24 -0.36 3.02e-12 Cognitive function; LIHC cis rs7100689 0.622 rs1340383 chr10:82095968 T/G cg00277334 chr10:82204260 NA -0.56 -7.08 -0.36 8.39e-12 Post bronchodilator FEV1; LIHC cis rs10857712 0.904 rs36118799 chr10:135222369 T/G cg19623624 chr10:135278901 LOC619207 -0.42 -6.52 -0.33 2.55e-10 Systemic lupus erythematosus; LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.7 0.38 1.5e-13 Prudent dietary pattern; LIHC cis rs909341 0.868 rs2738758 chr20:62349625 C/G cg03999872 chr20:62272968 STMN3 0.43 6.54 0.33 2.24e-10 Atopic dermatitis; LIHC cis rs8017423 0.967 rs61996919 chr14:90701803 A/C cg04374321 chr14:90722782 PSMC1 0.74 14.42 0.61 3.67e-37 Mortality in heart failure; LIHC cis rs8141529 0.748 rs132533 chr22:29299571 A/G cg15103426 chr22:29168792 CCDC117 -0.58 -9.43 -0.45 6.59e-19 Lymphocyte counts; LIHC cis rs3135071 1.000 rs3135071 chr4:2406321 C/T cg08330972 chr4:2403930 ZFYVE28 0.52 6.14 0.31 2.33e-9 Influenza A (H1N1) severity; LIHC trans rs7246657 0.943 rs2126977 chr19:37995747 C/G cg10208301 chr11:6592745 DNHD1 -0.45 -6.48 -0.33 3.29e-10 Coronary artery calcification; LIHC cis rs9596863 1.000 rs1379833 chr13:54443167 C/T ch.13.53330881F chr13:54432880 NA 0.44 5.86 0.3 1.07e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs61931739 0.500 rs6488222 chr12:34526289 G/A cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs2404602 0.583 rs12908334 chr15:76581592 C/T cg22467129 chr15:76604101 ETFA -0.38 -6.36 -0.33 6.52e-10 Blood metabolite levels; LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.27 0.61 1.39e-36 Prudent dietary pattern; LIHC cis rs7107174 1.000 rs4944195 chr11:78003499 T/C cg02023728 chr11:77925099 USP35 0.5 9.55 0.46 2.56e-19 Testicular germ cell tumor; LIHC cis rs4901869 0.966 rs9972208 chr14:59336116 C/T cg02291164 chr14:59296302 NA 0.48 6.06 0.31 3.64e-9 Panic disorder; LIHC cis rs1691799 0.867 rs1168339 chr12:66759236 T/G cg16791601 chr12:66731901 HELB -0.54 -13.09 -0.58 5.17e-32 White blood cell count (basophil); LIHC cis rs7762018 0.891 rs7764839 chr6:170146351 C/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.77 0.34 5.71e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg14343924 chr8:8086146 FLJ10661 -0.42 -5.98 -0.31 5.61e-9 Neuroticism; LIHC cis rs243505 0.632 rs887571 chr7:148505253 G/A cg09806900 chr7:148480153 CUL1 0.44 6.52 0.33 2.52e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1395 0.885 rs7575245 chr2:27527321 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.17 -0.32 1.91e-9 Blood metabolite levels; LIHC cis rs208520 0.690 rs4618506 chr6:66756889 A/C cg07460842 chr6:66804631 NA -0.75 -8.43 -0.41 1.01e-15 Exhaled nitric oxide output; LIHC cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg03806693 chr22:41940476 POLR3H -1.02 -10.72 -0.5 2.53e-23 Vitiligo; LIHC cis rs4450131 0.868 rs10794175 chr10:126358073 G/T cg20435097 chr10:126320824 FAM53B 0.51 9.01 0.44 1.44e-17 White blood cell count (basophil); LIHC cis rs2629540 0.855 rs12776722 chr10:126469833 G/A cg08799069 chr10:126477246 METTL10 0.5 7.66 0.38 1.97e-13 Cocaine dependence; LIHC cis rs4144743 0.941 rs7222617 chr17:45324080 G/T cg18085866 chr17:45331354 ITGB3 -0.59 -8.53 -0.42 4.87e-16 Body mass index; LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg05527609 chr1:210001259 C1orf107 0.4 6.33 0.32 7.83e-10 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg13047869 chr3:10149882 C3orf24 0.54 6.32 0.32 8.27e-10 Alzheimer's disease; LIHC cis rs1552244 0.515 rs111560858 chr3:10166845 G/A cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs7617773 0.817 rs17786132 chr3:48249420 C/G cg11946769 chr3:48343235 NME6 0.89 11.14 0.52 8.2e-25 Coronary artery disease; LIHC cis rs116248771 0.739 rs2082159 chr3:158359667 C/T cg16708174 chr3:158430962 RARRES1 0.48 6.42 0.33 4.46e-10 diarrhoeal disease at age 2; LIHC cis rs2976388 0.967 rs2976397 chr8:143764613 G/T cg06565975 chr8:143823917 SLURP1 -0.31 -5.85 -0.3 1.14e-8 Urinary tract infection frequency; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg07568779 chr8:15398233 TUSC3 -0.44 -6.16 -0.32 2e-9 Monocyte count; LIHC cis rs6545883 0.894 rs6734628 chr2:61451260 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.29 -0.37 2.16e-12 Tuberculosis; LIHC cis rs6456156 0.586 rs9457266 chr6:167482555 T/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.57 -0.42 3.73e-16 Primary biliary cholangitis; LIHC cis rs9457247 0.871 rs1811121 chr6:167403539 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 10.02 0.48 6.67e-21 Crohn's disease; LIHC cis rs11098499 0.821 rs28665282 chr4:120384186 C/T cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs9381040 0.655 rs2294696 chr6:41036988 A/G cg04346459 chr6:41068666 NFYA;LOC221442 0.42 6.76 0.34 6.12e-11 Alzheimer's disease (late onset); LIHC cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg23205692 chr1:25664452 TMEM50A 0.4 6.53 0.33 2.32e-10 Erythrocyte sedimentation rate; LIHC cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg05025164 chr4:1340916 KIAA1530 -0.39 -5.84 -0.3 1.24e-8 Obesity-related traits; LIHC cis rs5771242 1.000 rs5771242 chr22:50661869 T/C cg16473166 chr22:50639996 SELO 0.61 7.08 0.36 8.18e-12 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); LIHC trans rs916888 0.821 rs199505 chr17:44859410 A/G cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6665290 0.904 rs6690803 chr1:227189106 C/T cg10327440 chr1:227177885 CDC42BPA -1.14 -30.24 -0.85 1.18e-98 Myeloid white cell count; LIHC cis rs10791097 0.694 rs61910787 chr11:130744473 G/A cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10256972 0.706 rs12701969 chr7:1121849 A/G cg23978390 chr7:1156363 C7orf50 0.57 8.62 0.42 2.56e-16 Longevity;Endometriosis; LIHC cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg08888203 chr3:10149979 C3orf24 0.62 6.74 0.34 6.91e-11 Alzheimer's disease; LIHC cis rs3770081 1.000 rs76297018 chr2:86227007 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -8.52 -0.42 5.32e-16 Facial emotion recognition (sad faces); LIHC cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg20818283 chr2:191399100 TMEM194B -0.45 -6.1 -0.31 2.91e-9 Pulse pressure; LIHC cis rs2834188 0.924 rs2834177 chr21:34676806 T/C cg14352951 chr21:34696688 IFNAR1 0.48 6.7 0.34 8.71e-11 Narcolepsy; LIHC cis rs894734 0.535 rs2366142 chr12:54323148 T/C cg17410650 chr12:54324560 NA -0.42 -8.26 -0.41 3.21e-15 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs7937682 0.889 rs1789355 chr11:111499718 T/C cg09085632 chr11:111637200 PPP2R1B -1.03 -12.24 -0.55 7.9e-29 Primary sclerosing cholangitis; LIHC trans rs1005277 0.579 rs1780137 chr10:38501475 C/G cg23533926 chr12:111358616 MYL2 -0.33 -6.19 -0.32 1.73e-9 Extrinsic epigenetic age acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05108160 chr13:110790284 NA 0.43 6.92 0.35 2.23e-11 Cognitive function; LIHC cis rs1008375 1.000 rs10805357 chr4:17652352 G/A cg16339924 chr4:17578868 LAP3 0.44 6.28 0.32 1.04e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9486715 0.964 rs6921480 chr6:97066329 C/G cg18709589 chr6:96969512 KIAA0776 -0.35 -6.05 -0.31 3.81e-9 Headache; LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs8044995 0.563 rs8058517 chr16:68379860 A/G cg09835421 chr16:68378352 PRMT7 0.67 8.27 0.41 3.08e-15 Schizophrenia; LIHC cis rs2153535 0.580 rs7767780 chr6:8453462 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.46 0.42 7.87e-16 Motion sickness; LIHC trans rs1509701 0.898 rs11802622 chr1:239195698 A/T cg02310027 chr17:77704741 ENPP7 0.4 6.2 0.32 1.62e-9 Shingles; LIHC cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg02359409 chr6:42947317 PEX6 -0.48 -6.78 -0.34 5.42e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3106136 0.967 rs17310266 chr4:95177051 T/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.88 -0.39 4.27e-14 Capecitabine sensitivity; LIHC cis rs1057239 0.739 rs1014554 chr1:175133626 A/G cg00958927 chr1:175162553 KIAA0040 0.39 6.55 0.33 2.06e-10 Diastolic blood pressure; LIHC cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.38 -8.43 -0.41 9.44e-16 Calcium levels; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC trans rs1814175 0.646 rs1722010 chr11:49897958 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC trans rs2727020 0.538 rs61885230 chr11:49128958 T/C cg03929089 chr4:120376271 NA -0.49 -7.65 -0.38 2.06e-13 Coronary artery disease; LIHC cis rs7615952 0.932 rs13086087 chr3:125646281 A/C cg05084668 chr3:125655381 ALG1L -0.6 -8.59 -0.42 3.16e-16 Blood pressure (smoking interaction); LIHC cis rs4332037 0.707 rs10268797 chr7:1873756 C/G cg23422044 chr7:1970798 MAD1L1 0.57 6.82 0.35 4.19e-11 Bipolar disorder; LIHC cis rs12594515 0.874 rs8032878 chr15:45998015 A/G cg19682013 chr15:45996608 NA 0.39 6.63 0.34 1.29e-10 Waist circumference;Weight; LIHC cis rs17401966 1.000 rs11578788 chr1:10422958 A/G cg19773385 chr1:10388646 KIF1B -0.51 -8.69 -0.43 1.49e-16 Hepatocellular carcinoma; LIHC cis rs7927592 0.956 rs6591341 chr11:68335478 C/T cg16797656 chr11:68205561 LRP5 0.52 8.38 0.41 1.43e-15 Total body bone mineral density; LIHC cis rs11122272 0.735 rs2739513 chr1:231515201 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.86 -0.51 8.4e-24 Hemoglobin concentration; LIHC cis rs2845885 1.000 rs2845885 chr11:63869062 A/G cg05555928 chr11:63887634 MACROD1 -0.46 -6.0 -0.31 5.13e-9 Body mass index; LIHC cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg18867708 chr6:26865862 GUSBL1 0.56 8.32 0.41 2.16e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs1577917 0.727 rs9344539 chr6:86353621 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.36 -6.47 -0.33 3.45e-10 Response to antipsychotic treatment; LIHC cis rs9733 0.715 rs7534124 chr1:150739073 C/T cg18016565 chr1:150552671 MCL1 -0.49 -9.43 -0.45 6.5e-19 Tonsillectomy; LIHC cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.97 -0.31 5.92e-9 Colorectal cancer; LIHC cis rs6952808 0.792 rs12531315 chr7:1953650 C/G cg20295408 chr7:1910781 MAD1L1 -0.5 -7.16 -0.36 4.84e-12 Bipolar disorder and schizophrenia; LIHC cis rs990171 0.571 rs3771202 chr2:102772669 C/G cg22835712 chr2:102737379 NA 0.5 7.09 0.36 7.95e-12 Lymphocyte counts; LIHC cis rs7312933 0.670 rs10880269 chr12:42606135 C/T cg17420585 chr12:42539391 GXYLT1 -0.36 -5.9 -0.3 8.96e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.5 0.38 5.37e-13 Electroencephalogram traits; LIHC cis rs1190552 0.846 rs1044503 chr14:102965996 A/G cg10241871 chr14:102965420 TECPR2 -0.49 -7.6 -0.38 2.94e-13 Blood protein levels; LIHC cis rs11148252 0.740 rs9596642 chr13:52900879 A/G cg00495681 chr13:53174319 NA -0.39 -5.99 -0.31 5.19e-9 Lewy body disease; LIHC cis rs1865721 0.804 rs3826652 chr18:73142153 C/T cg26385618 chr18:73139727 C18orf62 0.29 7.75 0.39 1.08e-13 Intelligence; LIHC cis rs1348850 0.526 rs6718769 chr2:178450909 T/C cg27490568 chr2:178487706 NA 0.98 11.39 0.52 1.1e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2243480 1.000 rs1638734 chr7:66097539 A/C cg18252515 chr7:66147081 NA -1.32 -17.62 -0.69 6.64e-50 Diabetic kidney disease; LIHC cis rs11690935 0.549 rs796839 chr2:172916214 A/C cg13550731 chr2:172543902 DYNC1I2 0.54 9.23 0.45 2.97e-18 Schizophrenia; LIHC cis rs7599312 0.534 rs2371615 chr2:213405660 G/T cg16329650 chr2:213403929 ERBB4 0.59 7.13 0.36 6.07e-12 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11760633 0.502 rs36020539 chr7:1823203 A/T cg23422044 chr7:1970798 MAD1L1 -0.36 -5.73 -0.3 2.16e-8 Coronary artery disease; LIHC trans rs1814175 0.817 rs7929173 chr11:49944007 T/C cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs4665809 1.000 rs6720314 chr2:26334852 G/A cg04944784 chr2:26401820 FAM59B -0.68 -8.6 -0.42 2.89e-16 Gut microbiome composition (summer); LIHC cis rs2895526 0.521 rs6602606 chr10:12713901 C/T cg00115178 chr10:12648176 CAMK1D -0.38 -6.54 -0.33 2.23e-10 Headache; LIHC cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg00934597 chr7:893267 UNC84A -0.65 -9.74 -0.47 5.86e-20 Perceived unattractiveness to mosquitoes; LIHC cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs651907 0.535 rs13085776 chr3:101505507 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.45 -5.79 -0.3 1.61e-8 Colorectal cancer; LIHC trans rs60752752 0.852 rs61803340 chr1:153369833 A/C cg14901121 chr8:98817630 LAPTM4B -0.43 -7.17 -0.36 4.6e-12 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs10197940 0.662 rs72860233 chr2:152289767 G/A cg19508488 chr2:152266495 RIF1 0.6 8.38 0.41 1.39e-15 Lung cancer; LIHC cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg22800045 chr5:56110881 MAP3K1 0.68 8.75 0.43 1.02e-16 Initial pursuit acceleration; LIHC cis rs11608355 0.545 rs2302709 chr12:109893697 A/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs10752881 1.000 rs10752881 chr1:182973491 A/G ch.1.3577855R chr1:183094577 LAMC1 0.57 9.81 0.47 3.65e-20 Colorectal cancer; LIHC cis rs6500602 0.789 rs2404546 chr16:4479734 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.51 0.33 2.69e-10 Schizophrenia; LIHC cis rs12908161 1.000 rs35316992 chr15:85248133 A/G cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg03517284 chr6:25882590 NA -0.5 -6.0 -0.31 5e-9 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg06238570 chr21:40685208 BRWD1 -0.56 -6.53 -0.33 2.35e-10 Cognitive function; LIHC cis rs743757 0.938 rs2236959 chr3:50441627 T/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.48 6.78 0.34 5.2e-11 Diastolic blood pressure; LIHC cis rs57590327 0.679 rs1907880 chr3:81567861 C/T cg07356753 chr3:81810745 GBE1 -0.45 -6.14 -0.32 2.28e-9 Extraversion; LIHC cis rs9916302 0.904 rs2061338 chr17:37421767 T/C cg03013999 chr17:37608204 MED1 0.36 6.03 0.31 4.18e-9 Glomerular filtration rate (creatinine); LIHC cis rs13394619 0.936 rs9789414 chr2:11724684 A/G cg07314298 chr2:11723111 GREB1 -0.49 -9.52 -0.46 3.32e-19 Endometriosis; LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg09455208 chr3:40491958 NA 0.42 8.51 0.42 5.4e-16 Renal cell carcinoma; LIHC cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg06481639 chr22:41940642 POLR3H -0.65 -6.6 -0.34 1.57e-10 Vitiligo; LIHC cis rs10431058 0.965 rs1939895 chr11:107483469 C/T cg18204760 chr11:107461044 ELMOD1;LOC643923 0.39 6.24 0.32 1.3e-9 Common traits (Other); LIHC cis rs1568889 0.938 rs7128045 chr11:28190180 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.52 7.22 0.36 3.34e-12 Bipolar disorder; LIHC cis rs7683537 0.673 rs1401363 chr4:185643862 A/G cg04058563 chr4:185651563 MLF1IP 0.77 7.79 0.39 8.15e-14 Systemic lupus erythematosus; LIHC cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg11890956 chr21:40555474 PSMG1 1.06 15.78 0.65 1.58e-42 Cognitive function; LIHC cis rs2425143 1.000 rs13038622 chr20:34319343 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs7249142 0.549 rs3787040 chr19:19297292 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.39 -6.56 -0.33 1.95e-10 IgG glycosylation; LIHC cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg05555928 chr11:63887634 MACROD1 0.54 7.16 0.36 4.95e-12 Mean platelet volume; LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg27432699 chr2:27873401 GPN1 -0.53 -7.59 -0.38 2.98e-13 Total body bone mineral density; LIHC cis rs6951245 0.786 rs77943789 chr7:1140158 C/T cg24642844 chr7:1081250 C7orf50 -0.73 -7.56 -0.38 3.86e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2439831 0.681 rs478104 chr15:43594900 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.9 17.03 0.68 1.64e-47 Lung cancer in ever smokers; LIHC trans rs4927850 0.958 rs1975582 chr3:195751439 G/T cg16724585 chr3:197361211 NA -0.47 -6.61 -0.34 1.46e-10 Pancreatic cancer; LIHC cis rs2953174 0.786 rs2953177 chr2:241516616 A/G cg07929629 chr2:241523174 NA 0.59 6.83 0.35 3.85e-11 Bipolar disorder; LIHC cis rs4819052 0.851 rs10470247 chr21:46659018 T/C cg22633049 chr21:46681294 NA -0.37 -6.31 -0.32 8.65e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs116095464 0.558 rs7708515 chr5:234989 C/G cg00938859 chr5:1591904 SDHAP3 0.56 7.15 0.36 5.34e-12 Breast cancer; LIHC cis rs7618501 0.521 rs11130222 chr3:49901060 A/T cg21467203 chr3:49911342 NA -0.61 -11.17 -0.52 6.36e-25 Intelligence (multi-trait analysis); LIHC cis rs61440199 1.000 rs73818808 chr3:20136085 T/C cg00235661 chr3:20228976 SGOL1 -0.41 -5.8 -0.3 1.48e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs8056893 0.714 rs1465468 chr16:68398290 A/G cg02226672 chr16:68398533 SMPD3 0.43 6.13 0.31 2.42e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs9322817 0.691 rs9391241 chr6:105223663 T/C cg02098413 chr6:105308735 HACE1 -0.42 -7.55 -0.38 4.01e-13 Thyroid stimulating hormone; LIHC cis rs4689592 0.587 rs6825954 chr4:7074226 T/C cg19539972 chr4:7069911 GRPEL1 0.69 9.96 0.47 1.06e-20 Monocyte percentage of white cells; LIHC cis rs10751667 1.000 rs7395632 chr11:958789 C/T cg10932868 chr11:921992 NA -0.31 -5.79 -0.3 1.61e-8 Alzheimer's disease (late onset); LIHC cis rs7395581 0.918 rs7124955 chr11:47315274 A/T cg26139080 chr11:47293733 MADD -0.49 -8.03 -0.4 1.57e-14 HDL cholesterol; LIHC cis rs17102423 0.731 rs7145112 chr14:65534084 A/C cg16583315 chr14:65563665 MAX -0.38 -7.26 -0.37 2.6e-12 Obesity-related traits; LIHC cis rs2439831 0.867 rs496584 chr15:43831923 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.71 11.16 0.52 6.93e-25 Lung cancer in ever smokers; LIHC cis rs903552 1.000 rs12906575 chr15:102003617 G/A cg00659931 chr15:102010125 PCSK6 -0.44 -5.96 -0.31 6.15e-9 Diabetic kidney disease; LIHC cis rs742614 0.533 rs6059498 chr20:32447282 T/C cg06304546 chr20:32448765 NA -0.42 -5.89 -0.3 9.11e-9 Stearic acid (18:0) levels; LIHC cis rs17152411 0.600 rs7902120 chr10:126679739 C/T cg07906193 chr10:126599966 NA -0.29 -5.74 -0.3 2.07e-8 Height; LIHC cis rs17253792 0.598 rs35830444 chr14:56017350 T/C cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs611744 0.647 rs1584373 chr8:109263399 C/A cg18478394 chr8:109455254 TTC35 0.42 7.24 0.36 2.98e-12 Dupuytren's disease; LIHC cis rs10751667 0.666 rs11246357 chr11:963980 A/C ch.11.42038R chr11:967971 AP2A2 0.55 10.0 0.48 7.97e-21 Alzheimer's disease (late onset); LIHC cis rs546131 0.928 rs535719 chr11:34853382 A/G cg06937548 chr11:34938143 PDHX;APIP 0.6 8.18 0.4 5.48e-15 Lung disease severity in cystic fibrosis; LIHC cis rs10911363 0.659 rs6669960 chr1:183436577 C/G cg09173681 chr1:183549694 NCF2 -0.57 -9.88 -0.47 2.02e-20 Systemic lupus erythematosus; LIHC trans rs79976124 0.876 rs17511913 chr6:66644361 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.76 0.34 5.97e-11 Type 2 diabetes; LIHC cis rs778371 0.788 rs2675959 chr2:233791988 T/A cg08000102 chr2:233561755 GIGYF2 -0.78 -7.89 -0.39 4.02e-14 Schizophrenia; LIHC cis rs7584330 0.666 rs937386 chr2:238364039 C/T cg14458575 chr2:238380390 NA 0.53 7.53 0.38 4.48e-13 Prostate cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13494355 chr1:1274420 DVL1 0.42 6.47 0.33 3.42e-10 Longevity; LIHC cis rs6088590 0.735 rs6088618 chr20:33409350 G/A cg07148914 chr20:33460835 GGT7 0.44 5.89 0.3 9.1e-9 Coronary artery disease; LIHC cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.84 0.35 3.73e-11 Bipolar disorder; LIHC cis rs9300255 0.510 rs1790109 chr12:123637752 C/G cg00376283 chr12:123451042 ABCB9 0.65 7.4 0.37 1.08e-12 Neutrophil percentage of white cells; LIHC cis rs4788570 0.615 rs10852503 chr16:71652227 G/C cg06353428 chr16:71660113 MARVELD3 1.45 15.74 0.65 2.22e-42 Intelligence (multi-trait analysis); LIHC cis rs4268898 0.560 rs78711174 chr2:24496531 G/A cg06627628 chr2:24431161 ITSN2 -0.74 -9.78 -0.47 4.28e-20 Asthma; LIHC cis rs10508774 1.000 rs957219 chr10:32931910 A/G cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7296418 0.619 rs7139321 chr12:123719528 T/G cg00376283 chr12:123451042 ABCB9 0.65 10.61 0.5 6.14e-23 Platelet count; LIHC cis rs9457247 0.529 rs6907666 chr6:167523395 A/G cg07741184 chr6:167504864 NA -0.26 -6.37 -0.33 6.24e-10 Crohn's disease; LIHC cis rs7618501 0.602 rs2071207 chr3:50159844 T/C cg21467203 chr3:49911342 NA 0.44 7.76 0.39 1.01e-13 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.709 rs11072591 chr15:76649562 A/G cg03037974 chr15:76606532 NA 0.65 11.45 0.53 6.56e-26 Blood metabolite levels; LIHC cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg00684032 chr4:1343700 KIAA1530 0.39 6.67 0.34 1.04e-10 Obesity-related traits; LIHC cis rs7224685 0.539 rs2054039 chr17:4014538 C/A cg09695851 chr17:3907499 NA 0.67 11.13 0.52 8.99e-25 Type 2 diabetes; LIHC cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg11890956 chr21:40555474 PSMG1 -0.56 -9.09 -0.44 8.42e-18 Cognitive function; LIHC cis rs875971 0.862 rs880166 chr7:65670762 T/C cg11764359 chr7:65958608 NA -0.82 -13.9 -0.6 4.09e-35 Aortic root size; LIHC cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg02475777 chr4:1388615 CRIPAK 0.55 8.29 0.41 2.62e-15 Longevity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18593717 chr1:156722068 HDGF -0.43 -6.34 -0.32 7.17e-10 Pancreatic cancer; LIHC cis rs3806843 0.900 rs2563279 chr5:140131535 G/A cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9309711 0.623 rs4641971 chr2:3481857 A/C cg04359351 chr2:3481828 TTC15 -0.29 -5.8 -0.3 1.48e-8 Neurofibrillary tangles; LIHC cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg11890956 chr21:40555474 PSMG1 -0.5 -8.05 -0.4 1.39e-14 Cognitive function; LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.62 0.56 3.02e-30 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg07424592 chr7:64974309 NA -0.8 -9.29 -0.45 1.82e-18 Diabetic kidney disease; LIHC cis rs870825 0.616 rs7678949 chr4:185635018 G/C cg04058563 chr4:185651563 MLF1IP 0.69 7.21 0.36 3.66e-12 Blood protein levels; LIHC cis rs7474896 0.609 rs1830612 chr10:37999883 A/G cg25427524 chr10:38739819 LOC399744 -0.49 -7.24 -0.36 3.04e-12 Obesity (extreme); LIHC cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.49e-11 Diabetic kidney disease; LIHC cis rs1707322 0.752 rs3811436 chr1:46125880 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.57 0.38 3.45e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7959452 0.562 rs11177630 chr12:69767963 G/C cg20891283 chr12:69753455 YEATS4 0.9 19.37 0.72 6.1900000000000006e-57 Blood protein levels; LIHC cis rs644799 0.625 rs1255177 chr11:95471495 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.62 10.19 0.48 1.85e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7412746 0.658 rs4537557 chr1:150734436 A/G cg18016565 chr1:150552671 MCL1 0.54 10.05 0.48 5.25e-21 Melanoma; LIHC cis rs7100689 0.646 rs1340376 chr10:82128963 A/G cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs8114671 0.836 rs6060140 chr20:33566507 G/A cg07148914 chr20:33460835 GGT7 0.56 8.47 0.42 7.28e-16 Height; LIHC trans rs12478296 0.534 rs67092377 chr2:243002171 T/G cg01596870 chr19:55963115 NA -0.67 -9.82 -0.47 3.31e-20 Obesity-related traits; LIHC cis rs6424115 0.737 rs10917430 chr1:24170458 C/T cg08896387 chr1:24191740 FUCA1 0.42 6.75 0.34 6.43e-11 Immature fraction of reticulocytes; LIHC cis rs754466 0.580 rs10824577 chr10:79577408 G/C cg17075019 chr10:79541650 NA -0.8 -12.68 -0.57 1.78e-30 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7772486 0.754 rs9390356 chr6:146118983 A/T cg05347473 chr6:146136440 FBXO30 -0.39 -6.22 -0.32 1.46e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs16958440 1.000 rs2289131 chr18:44602864 G/A cg17192377 chr18:44677553 HDHD2 0.59 6.52 0.33 2.56e-10 Sitting height ratio; LIHC cis rs950776 0.506 rs12915366 chr15:78831753 G/A cg22563815 chr15:78856949 CHRNA5 0.36 6.45 0.33 3.9e-10 Sudden cardiac arrest; LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg27432699 chr2:27873401 GPN1 -0.49 -7.07 -0.36 8.55e-12 Total body bone mineral density; LIHC cis rs7552404 0.924 rs1858536 chr1:76161595 G/T cg22875332 chr1:76189707 ACADM 0.48 7.45 0.37 7.7e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7044106 0.708 rs10760113 chr9:123474050 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.07 0.51 1.49e-24 Hip circumference adjusted for BMI; LIHC cis rs2370759 1.000 rs7910776 chr10:32639093 C/T cg05361325 chr10:32636312 EPC1 -0.48 -5.87 -0.3 1e-8 Sexual dysfunction (female); LIHC cis rs10193935 0.582 rs13394853 chr2:42630900 T/C cg27598129 chr2:42591480 NA -0.7 -10.83 -0.51 1.06e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs9790314 0.905 rs6774276 chr3:160941318 C/T cg03342759 chr3:160939853 NMD3 -0.74 -9.61 -0.46 1.59e-19 Morning vs. evening chronotype; LIHC cis rs2242116 0.932 rs4683301 chr3:46931478 A/T cg23352942 chr3:46931381 PTH1R 0.34 9.12 0.44 6.58e-18 Birth weight; LIHC cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg24531977 chr5:56204891 C5orf35 -0.63 -8.95 -0.44 2.26e-17 Initial pursuit acceleration; LIHC cis rs2073499 0.935 rs3755832 chr3:50305234 G/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.75 8.03 0.4 1.61e-14 Schizophrenia; LIHC cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg18867708 chr6:26865862 GUSBL1 -0.57 -8.61 -0.42 2.71e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs13064411 0.696 rs9814395 chr3:113188885 C/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.09e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs4243830 0.850 rs4908558 chr1:6584101 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.83 -9.98 -0.47 9.42e-21 Body mass index; LIHC cis rs644799 1.000 rs488246 chr11:95560473 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7208859 0.673 rs73263981 chr17:28920502 A/G cg14067834 chr17:29058358 SUZ12P 0.63 6.65 0.34 1.15e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs4906332 1.000 rs12896919 chr14:103956713 T/C cg17675199 chr6:35436792 RPL10A 0.35 6.89 0.35 2.76e-11 Coronary artery disease; LIHC cis rs4727027 0.933 rs12532104 chr7:148864233 A/C cg23583168 chr7:148888333 NA -0.73 -10.28 -0.49 9.12e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg18306943 chr3:40428807 ENTPD3 -0.44 -7.81 -0.39 6.94e-14 Renal cell carcinoma; LIHC cis rs9309473 0.528 rs11126395 chr2:73564964 A/G cg20560298 chr2:73613845 ALMS1 -0.46 -7.32 -0.37 1.82e-12 Metabolite levels; LIHC cis rs4925386 0.759 rs2427293 chr20:60925859 A/G cg06026331 chr20:60912101 LAMA5 -0.62 -9.08 -0.44 8.74e-18 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg11764359 chr7:65958608 NA 0.56 6.0 0.31 5.17e-9 Diabetic kidney disease; LIHC cis rs9457247 0.510 rs6456151 chr6:167471851 A/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.69 -0.43 1.56e-16 Crohn's disease; LIHC cis rs1348850 0.632 rs11682717 chr2:178499240 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.99 0.4 2.13e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6430585 0.697 rs6724569 chr2:136516970 G/A cg07169764 chr2:136633963 MCM6 1.15 16.08 0.66 9.8e-44 Corneal structure; LIHC cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg21724239 chr8:58056113 NA 0.56 7.03 0.36 1.1e-11 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.735 rs2790877 chr1:231535427 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.25 0.45 2.51e-18 Hemoglobin concentration; LIHC trans rs28735056 0.584 rs35614280 chr18:77636679 C/G cg05926928 chr17:57297772 GDPD1 0.71 8.98 0.44 1.82e-17 Schizophrenia; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg09148494 chr19:55866345 COX6B2;FAM71E2 0.43 6.16 0.32 2.01e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs11031096 0.782 rs10767845 chr11:4156922 C/T cg18678763 chr11:4115507 RRM1 -0.58 -8.66 -0.42 1.92e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1055129 0.537 rs1135640 chr17:73949540 C/G cg10935138 chr17:73851978 WBP2 -0.5 -7.38 -0.37 1.23e-12 White matter hyperintensity burden; LIHC cis rs12497850 1.000 rs4858828 chr3:48724811 C/T cg06212747 chr3:49208901 KLHDC8B 0.5 6.58 0.34 1.81e-10 Parkinson's disease; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg15212038 chr4:7032128 TBC1D14 0.52 6.24 0.32 1.27e-9 Lung function (FEV1); LIHC cis rs9302635 0.513 rs8050238 chr16:72154187 C/T cg16558253 chr16:72132732 DHX38 -0.46 -6.79 -0.34 5e-11 Blood protein levels; LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg14893161 chr1:205819251 PM20D1 0.66 9.68 0.46 9.45e-20 Menarche (age at onset); LIHC trans rs1005277 0.579 rs2474594 chr10:38426661 G/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg02359409 chr6:42947317 PEX6 -0.47 -6.23 -0.32 1.39e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.11e-8 Bipolar disorder; LIHC cis rs7772486 0.875 rs2777477 chr6:146305491 A/G cg23711669 chr6:146136114 FBXO30 0.59 10.12 0.48 3.02e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs4690686 0.731 rs11941845 chr4:177276526 G/A cg17059388 chr4:177262070 NA 0.36 6.61 0.34 1.46e-10 Essential tremor; LIHC cis rs992157 0.661 rs10171839 chr2:219051314 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.74 11.81 0.54 3.2e-27 Colorectal cancer; LIHC cis rs2832191 0.703 rs2853827 chr21:30443596 T/C cg24692254 chr21:30365293 RNF160 0.87 15.47 0.64 2.69e-41 Dental caries; LIHC cis rs9814567 1.000 rs9850015 chr3:134269541 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg02353165 chr6:42928485 GNMT 0.77 12.02 0.55 5.25e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg18357526 chr6:26021779 HIST1H4A 0.58 8.01 0.4 1.85e-14 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07192821 chr15:45003560 B2M 0.43 6.28 0.32 1.01e-9 Cognitive function; LIHC cis rs4474465 1.000 rs10793316 chr11:78211928 C/A cg27205649 chr11:78285834 NARS2 0.38 5.77 0.3 1.74e-8 Alzheimer's disease (survival time); LIHC cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs763121 0.853 rs2413545 chr22:39092524 C/T cg06022373 chr22:39101656 GTPBP1 0.67 11.48 0.53 4.92e-26 Menopause (age at onset); LIHC cis rs35146811 0.586 rs6946168 chr7:99598286 C/T cg22906224 chr7:99728672 NA 0.49 6.57 0.33 1.88e-10 Coronary artery disease; LIHC cis rs9640161 0.702 rs1962004 chr7:150020381 G/A cg27494647 chr7:150038898 RARRES2 0.33 6.02 0.31 4.54e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs7659604 0.840 rs6821305 chr4:122713863 A/C cg20573242 chr4:122745356 CCNA2 0.45 6.81 0.35 4.47e-11 Type 2 diabetes; LIHC cis rs72827839 0.516 rs111630961 chr17:45938097 T/G cg02219949 chr17:45927392 SP6 0.43 5.73 0.3 2.26e-8 Ease of getting up in the morning; LIHC cis rs11958404 0.932 rs7706111 chr5:157416053 C/T cg05962755 chr5:157440814 NA 0.82 10.27 0.49 9.58e-22 IgG glycosylation; LIHC cis rs11711311 0.955 rs11715350 chr3:113418376 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.33 -5.74 -0.3 2.08e-8 IgG glycosylation; LIHC cis rs875971 0.895 rs778700 chr7:65866450 C/T cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs12971120 0.947 rs34676212 chr18:72170006 A/G cg25817165 chr18:72167213 CNDP2 -0.68 -12.74 -0.57 1.0500000000000001e-30 Refractive error; LIHC cis rs9649465 0.967 rs12537072 chr7:123377213 A/G cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.25e-15 Migraine; LIHC cis rs3823572 0.504 rs2346266 chr7:133639533 A/G cg03336402 chr7:133662267 EXOC4 0.46 5.75 0.3 2e-8 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.805 rs2838317 chr21:44991791 A/C cg04455712 chr21:45112962 RRP1B 0.45 7.81 0.39 6.97e-14 Mean corpuscular volume; LIHC cis rs7264396 0.563 rs61191623 chr20:34219987 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.55 -6.57 -0.33 1.84e-10 Total cholesterol levels; LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg03188948 chr7:1209495 NA 0.43 6.06 0.31 3.52e-9 Longevity;Endometriosis; LIHC cis rs60871478 1.000 rs4374882 chr7:821798 C/T cg04727924 chr7:799746 HEATR2 -0.58 -8.7 -0.43 1.37e-16 Cerebrospinal P-tau181p levels; LIHC cis rs2607426 0.681 rs1455434 chr19:41257046 G/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.53 -5.82 -0.3 1.32e-8 Blood protein levels; LIHC cis rs9359856 0.564 rs72915918 chr6:90430792 G/C cg13799429 chr6:90582589 CASP8AP2 -0.64 -6.05 -0.31 3.71e-9 Bipolar disorder; LIHC cis rs12497850 0.931 rs11920534 chr3:48937761 G/T cg07636037 chr3:49044803 WDR6 0.91 16.41 0.66 5.02e-45 Parkinson's disease; LIHC cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg12042659 chr19:58951599 ZNF132 0.36 5.94 0.31 6.89e-9 Uric acid clearance; LIHC cis rs12808519 0.646 rs12361755 chr11:69602646 C/T cg19831575 chr11:69590090 FGF4 0.47 6.55 0.33 2.11e-10 Urate levels in overweight individuals; LIHC cis rs546131 0.600 rs7946699 chr11:34820069 G/C cg11058730 chr11:34937778 PDHX;APIP 0.56 8.36 0.41 1.61e-15 Lung disease severity in cystic fibrosis; LIHC cis rs5997397 0.934 rs6005863 chr22:29156448 A/G cg02153584 chr22:29168773 CCDC117 0.5 7.61 0.38 2.65e-13 Red cell distribution width; LIHC cis rs9640161 0.750 rs11764936 chr7:150025915 G/T cg10018233 chr7:150070692 REPIN1 0.51 7.97 0.4 2.32e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs9814567 1.000 rs9289478 chr3:134268619 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7208859 0.573 rs7223803 chr17:29077193 A/G cg13385521 chr17:29058706 SUZ12P 0.81 7.96 0.4 2.64e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2839186 0.814 rs2839167 chr21:47661587 A/G cg05896524 chr21:47604654 C21orf56 0.49 7.7 0.38 1.48e-13 Testicular germ cell tumor; LIHC cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg22800045 chr5:56110881 MAP3K1 0.62 7.9 0.39 3.79e-14 Initial pursuit acceleration; LIHC cis rs2749592 0.550 rs10764135 chr10:37866845 C/T cg25427524 chr10:38739819 LOC399744 0.56 10.16 0.48 2.36e-21 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs826838 1.000 rs6582619 chr12:38729904 A/G cg13010199 chr12:38710504 ALG10B 0.65 7.88 0.39 4.33e-14 Heart rate; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg06873352 chr17:61820015 STRADA 0.74 13.34 0.58 5.88e-33 Prudent dietary pattern; LIHC cis rs6500602 0.647 rs1684600 chr16:4594671 C/T cg08645402 chr16:4508243 NA -0.37 -6.7 -0.34 8.6e-11 Schizophrenia; LIHC cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.85 -9.63 -0.46 1.43e-19 Platelet count; LIHC cis rs35110281 0.748 rs2838324 chr21:44999820 T/C cg21573476 chr21:45109991 RRP1B -0.59 -11.09 -0.51 1.25e-24 Mean corpuscular volume; LIHC cis rs2479724 0.870 rs6902650 chr6:41764080 G/A cg17623882 chr6:41773611 USP49 0.57 8.96 0.44 2.18e-17 Menarche (age at onset); LIHC cis rs9811920 0.609 rs7638900 chr3:99670773 T/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.87 -0.3 1.01e-8 Axial length; LIHC cis rs2370759 0.898 rs113412621 chr10:32579306 C/T cg05361325 chr10:32636312 EPC1 -0.52 -6.4 -0.33 5.13e-10 Sexual dysfunction (female); LIHC cis rs6952808 0.743 rs10266703 chr7:1918941 C/A cg21782813 chr7:2030301 MAD1L1 0.44 7.09 0.36 7.86e-12 Bipolar disorder and schizophrenia; LIHC cis rs7534824 0.543 rs12569174 chr1:101386179 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.65 7.35 0.37 1.49e-12 Refractive astigmatism; LIHC cis rs4423214 0.559 rs10898228 chr11:71228358 A/T cg05163923 chr11:71159392 DHCR7 -0.59 -7.27 -0.37 2.51e-12 Vitamin D levels; LIHC trans rs3960554 0.867 rs76408713 chr7:75829540 G/A cg19862616 chr7:65841803 NCRNA00174 0.56 7.48 0.37 6.26e-13 Eotaxin levels; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.99 0.31 5.4e-9 Menopause (age at onset); LIHC cis rs1443512 0.812 rs1992563 chr12:54330441 G/T cg17410650 chr12:54324560 NA -0.4 -7.22 -0.36 3.4e-12 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg11388866 chr21:40752116 WRB -0.45 -6.12 -0.31 2.5e-9 Hepatitis; LIHC cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg03806693 chr22:41940476 POLR3H -1.08 -11.42 -0.53 8.04e-26 Vitiligo; LIHC cis rs17818399 0.548 rs1989720 chr2:46854364 C/T cg02822958 chr2:46747628 ATP6V1E2 0.36 5.82 0.3 1.32e-8 Height; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg05484376 chr2:27715224 FNDC4 0.37 6.26 0.32 1.16e-9 Total body bone mineral density; LIHC cis rs9911578 0.935 rs420878 chr17:56709077 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.72 -0.43 1.26e-16 Intelligence (multi-trait analysis); LIHC cis rs3008870 0.755 rs2208577 chr1:67513574 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.48 8.34 0.41 1.84e-15 Lymphocyte percentage of white cells; LIHC trans rs17685 0.753 rs4732595 chr7:75755139 A/G cg19862616 chr7:65841803 NCRNA00174 0.91 18.37 0.7 6.44e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7617773 0.780 rs4511915 chr3:48343858 G/A cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs2404602 0.672 rs35374222 chr15:77071394 G/T cg03037974 chr15:76606532 NA -0.6 -10.01 -0.48 7.34e-21 Blood metabolite levels; LIHC cis rs921968 0.565 rs2037622 chr2:219609440 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.97e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3806843 1.000 rs13157397 chr5:140184442 G/A cg26395211 chr5:140044315 WDR55 -0.44 -6.49 -0.33 2.98e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs801193 0.569 rs10950050 chr7:66239588 A/C cg11764359 chr7:65958608 NA 0.73 12.54 0.56 6.41e-30 Aortic root size; LIHC cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg11764359 chr7:65958608 NA 0.55 5.82 0.3 1.35e-8 Diabetic kidney disease; LIHC trans rs2797160 0.904 rs2326292 chr6:125999674 G/A cg05039488 chr6:79577232 IRAK1BP1 -0.49 -6.9 -0.35 2.49e-11 Endometrial cancer; LIHC cis rs1577917 0.883 rs9450375 chr6:86756629 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.33 5.76 0.3 1.84e-8 Response to antipsychotic treatment; LIHC cis rs9296404 1 rs9296404 chr6:42925803 T/C cg13397359 chr6:42928475 GNMT 0.71 10.36 0.49 4.7e-22 Plasma homocysteine levels (post-methionine load test); LIHC cis rs2404602 0.583 rs35707798 chr15:76565026 G/C cg23625390 chr15:77176239 SCAPER 0.34 5.9 0.3 8.63e-9 Blood metabolite levels; LIHC cis rs9457247 0.967 rs2149083 chr6:167370971 G/C cg23791538 chr6:167370224 RNASET2 0.69 11.64 0.53 1.36e-26 Crohn's disease; LIHC cis rs4819052 0.851 rs9974891 chr21:46680767 T/A cg22633049 chr21:46681294 NA -0.35 -6.31 -0.32 8.69e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6089829 0.925 rs13041507 chr20:61666180 T/C cg08564027 chr20:61660810 NA 0.39 7.45 0.37 7.91e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs875971 0.545 rs73148639 chr7:65855329 A/T cg11764359 chr7:65958608 NA 0.59 8.43 0.41 9.64e-16 Aortic root size; LIHC cis rs4819052 0.851 rs2838840 chr21:46668494 A/G cg22633049 chr21:46681294 NA -0.37 -6.34 -0.32 7.41e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4474465 1.000 rs966456 chr11:78168603 T/A cg02023728 chr11:77925099 USP35 0.37 6.5 0.33 2.9e-10 Alzheimer's disease (survival time); LIHC cis rs35306767 0.903 rs12764024 chr10:922861 A/G cg20503657 chr10:835505 NA 0.97 11.23 0.52 4.15e-25 Eosinophil percentage of granulocytes; LIHC cis rs3015497 0.648 rs10144512 chr14:51082271 A/C cg09863266 chr14:51125203 SAV1 -0.38 -6.08 -0.31 3.15e-9 Mean platelet volume; LIHC cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg13395646 chr4:1353034 KIAA1530 -0.42 -6.33 -0.32 7.63e-10 Longevity; LIHC cis rs8067354 0.574 rs7219089 chr17:58032865 C/T cg13753209 chr17:57696993 CLTC 0.71 10.58 0.5 8.01e-23 Hemoglobin concentration; LIHC cis rs3806843 0.676 rs778591 chr5:140025484 G/A cg19875535 chr5:140030758 IK -0.43 -6.97 -0.35 1.61e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs1800469 1.000 rs1982072 chr19:41864509 T/A cg08477640 chr19:41863820 B9D2 0.36 6.08 0.31 3.27e-9 Colorectal cancer; LIHC cis rs6938 0.618 rs11638130 chr15:75183935 G/A cg14664628 chr15:75095509 CSK -0.46 -5.74 -0.3 2.05e-8 Breast cancer; LIHC cis rs244293 0.831 rs11079147 chr17:53094754 G/A cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.51 0.38 5.12e-13 Menarche (age at onset); LIHC cis rs66887589 0.777 rs10015883 chr4:120268146 A/G cg09307838 chr4:120376055 NA 0.48 7.42 0.37 9.58e-13 Diastolic blood pressure; LIHC cis rs10751667 0.666 rs7396473 chr11:966181 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs4891159 0.584 rs689878 chr18:74152017 C/T cg24786174 chr18:74118243 ZNF516 0.82 16.35 0.66 8.67e-45 Longevity; LIHC cis rs11190604 1.000 rs7085439 chr10:102210100 C/T cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1538970 0.816 rs4633317 chr1:45985157 T/C cg06784218 chr1:46089804 CCDC17 0.35 5.75 0.3 1.97e-8 Platelet count; LIHC cis rs8014204 0.804 rs35641442 chr14:75207263 G/A cg08847533 chr14:75593920 NEK9 0.35 5.91 0.3 8.21e-9 Caffeine consumption; LIHC cis rs9682041 0.740 rs6444929 chr3:170150076 C/T cg11886554 chr3:170076028 SKIL 0.85 6.26 0.32 1.14e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs933688 1.000 rs11950530 chr5:90688740 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.6 0.67 8.33e-46 Smoking behavior; LIHC cis rs2637266 0.935 rs2583048 chr10:78404507 C/G cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.32e-10 Pulmonary function; LIHC cis rs2836974 0.644 rs7281853 chr21:40693490 A/G cg11890956 chr21:40555474 PSMG1 -0.5 -7.96 -0.4 2.59e-14 Cognitive function; LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg21782813 chr7:2030301 MAD1L1 0.56 10.27 0.49 9.91e-22 Bipolar disorder and schizophrenia; LIHC cis rs11148252 0.595 rs9526968 chr13:53240183 T/C cg00495681 chr13:53174319 NA 0.68 12.15 0.55 1.69e-28 Lewy body disease; LIHC trans rs7613875 0.620 rs11721204 chr3:49982765 C/T cg21659725 chr3:3221576 CRBN 0.53 7.85 0.39 5.46e-14 Body mass index; LIHC cis rs4759375 1.000 rs10773003 chr12:123775127 A/G cg00376283 chr12:123451042 ABCB9 0.46 5.83 0.3 1.28e-8 HDL cholesterol; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg03721293 chr16:90014378 DEF8 0.4 6.78 0.34 5.4e-11 Skin colour saturation; LIHC cis rs3018712 0.532 rs2510398 chr11:68421416 G/A cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.17e-8 Total body bone mineral density; LIHC cis rs17401966 0.838 rs9332414 chr1:10326963 C/T cg19773385 chr1:10388646 KIF1B -0.42 -7.38 -0.37 1.2e-12 Hepatocellular carcinoma; LIHC cis rs317689 0.690 rs317630 chr12:69637847 T/C cg19645103 chr12:69753606 YEATS4 -0.44 -5.81 -0.3 1.44e-8 Response to diuretic therapy; LIHC cis rs6831352 0.879 rs36034266 chr4:100061388 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs1577917 1.000 rs12664335 chr6:86597774 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.6 10.87 0.51 7.73e-24 Response to antipsychotic treatment; LIHC trans rs916888 0.610 rs199446 chr17:44813169 G/A cg22968622 chr17:43663579 NA -0.49 -7.09 -0.36 7.64e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10779751 0.734 rs2261317 chr1:11124979 A/G cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs45544231 0.569 rs12443621 chr16:52548037 A/G cg09051775 chr16:52580266 TOX3 -0.32 -5.77 -0.3 1.81e-8 Restless legs syndrome; LIHC cis rs12477438 0.765 rs1115756 chr2:99659845 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs597539 0.617 rs598353 chr11:68635770 C/A cg04772025 chr11:68637568 NA 0.46 6.24 0.32 1.33e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.965 rs799917 chr17:41244936 G/A cg25072359 chr17:41440525 NA 0.42 6.77 0.34 5.73e-11 Menopause (age at onset); LIHC cis rs10870270 1.000 rs10159746 chr10:133742677 C/T cg08754478 chr10:133766260 PPP2R2D -0.55 -8.09 -0.4 1.04e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs1814175 0.935 rs28586931 chr11:49693872 G/A cg03929089 chr4:120376271 NA -0.89 -17.31 -0.68 1.19e-48 Height; LIHC cis rs2108622 0.727 rs9305069 chr19:15983386 A/G cg13772218 chr19:15982569 NA 0.37 7.61 0.38 2.7e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs4319547 0.737 rs10773176 chr12:122944713 A/G cg05707623 chr12:122985044 ZCCHC8 -0.59 -8.03 -0.4 1.57e-14 Body mass index; LIHC cis rs546131 0.600 rs502857 chr11:34854662 A/G cg11058730 chr11:34937778 PDHX;APIP 0.67 10.07 0.48 4.47e-21 Lung disease severity in cystic fibrosis; LIHC cis rs4561483 0.801 rs8061189 chr16:11951749 C/G cg08843971 chr16:11963173 GSPT1 0.42 8.35 0.41 1.76e-15 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg18252515 chr7:66147081 NA 1.2 16.12 0.66 6.97e-44 Diabetic kidney disease; LIHC cis rs921968 0.643 rs2243911 chr2:219529348 C/T cg02985541 chr2:219472218 PLCD4 -0.44 -7.99 -0.4 2.04e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs1816752 0.905 rs6490928 chr13:25014059 T/C cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg16405210 chr4:1374714 KIAA1530 0.45 5.71 0.3 2.39e-8 Obesity-related traits; LIHC cis rs929354 0.742 rs7807556 chr7:156934329 T/C cg17757837 chr7:157058334 UBE3C 0.69 10.75 0.5 1.98e-23 Body mass index; LIHC cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg09904177 chr6:26538194 HMGN4 0.57 11.35 0.52 1.45e-25 Intelligence (multi-trait analysis); LIHC cis rs7647973 0.925 rs9834003 chr3:49216472 T/C cg07636037 chr3:49044803 WDR6 0.52 6.62 0.34 1.38e-10 Menarche (age at onset); LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg11965913 chr1:205819406 PM20D1 0.64 9.34 0.45 1.24e-18 Menarche (age at onset); LIHC trans rs2744203 1.000 rs2473166 chr6:104643048 G/A cg27088726 chr16:83171155 CDH13 -0.45 -6.2 -0.32 1.66e-9 IgG glycosylation; LIHC cis rs1008375 0.932 rs6835077 chr4:17653285 A/T cg16339924 chr4:17578868 LAP3 0.53 6.98 0.35 1.57e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8060686 0.641 rs75450962 chr16:68210868 C/T cg05110241 chr16:68378359 PRMT7 -0.57 -6.52 -0.33 2.47e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs1552244 0.507 rs6443274 chr3:9995288 A/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.56 8.12 0.4 8.62e-15 Alzheimer's disease; LIHC cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg15691649 chr6:25882328 NA 0.48 6.72 0.34 7.63e-11 Blood metabolite levels; LIHC cis rs7647973 0.848 rs4955411 chr3:49145304 A/G cg07636037 chr3:49044803 WDR6 0.72 8.48 0.42 6.69e-16 Menarche (age at onset); LIHC cis rs6466055 0.932 rs7811681 chr7:104928869 A/G cg04380332 chr7:105027541 SRPK2 0.34 6.4 0.33 5.02e-10 Schizophrenia; LIHC cis rs600806 0.850 rs12073497 chr1:109974450 A/C cg16275483 chr1:110013120 SYPL2 -0.5 -6.2 -0.32 1.65e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs7707921 0.881 rs60733727 chr5:81448283 G/A cg15871215 chr5:81402204 ATG10 -0.61 -5.93 -0.31 7.3e-9 Breast cancer; LIHC cis rs7674212 0.510 rs55715738 chr4:104130189 A/G cg16532752 chr4:104119610 CENPE -0.46 -7.2 -0.36 3.81e-12 Type 2 diabetes; LIHC cis rs4853525 0.522 rs62179717 chr2:191590813 T/G cg10560079 chr2:191398806 TMEM194B -0.42 -5.75 -0.3 2.03e-8 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC trans rs7668874 0.779 rs7656260 chr4:116809546 T/G cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs908922 0.676 rs6658925 chr1:152482801 C/T cg20991723 chr1:152506922 NA -0.5 -8.84 -0.43 5.15e-17 Hair morphology; LIHC cis rs7264396 0.836 rs1886695 chr20:34180535 G/A cg04508476 chr20:34239394 CPNE1;RBM12 0.55 8.84 0.43 5.11e-17 Total cholesterol levels; LIHC cis rs12497850 0.931 rs7643368 chr3:48992855 T/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.19 0.36 4.06e-12 Parkinson's disease; LIHC cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg21724239 chr8:58056113 NA 0.64 7.32 0.37 1.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.534 rs1113736 chr7:1992992 T/C cg20295408 chr7:1910781 MAD1L1 -0.44 -6.57 -0.33 1.89e-10 Bipolar disorder and schizophrenia; LIHC cis rs36051895 0.664 rs10974960 chr9:5095842 G/A cg02405213 chr9:5042618 JAK2 -0.68 -11.7 -0.53 8.04e-27 Pediatric autoimmune diseases; LIHC cis rs7584330 0.554 rs112402109 chr2:238429058 A/G cg08992911 chr2:238395768 MLPH 0.55 6.44 0.33 4.12e-10 Prostate cancer; LIHC cis rs4478037 0.822 rs9863331 chr3:33123235 G/T cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.04 -0.36 1.05e-11 Major depressive disorder; LIHC cis rs10489202 0.513 rs4657731 chr1:168081255 C/T cg24449463 chr1:168025552 DCAF6 -0.54 -8.2 -0.41 5.01e-15 Schizophrenia; LIHC cis rs1559088 0.947 rs12461297 chr19:33559245 A/G cg27124370 chr19:33622961 WDR88 0.47 7.07 0.36 8.6e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs11098499 0.863 rs3733525 chr4:120447048 A/G cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC trans rs208520 0.690 rs1233103 chr6:66855943 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.47 -0.42 7.47e-16 Exhaled nitric oxide output; LIHC cis rs6466055 0.720 rs1204060 chr7:104963064 T/C cg04380332 chr7:105027541 SRPK2 0.37 6.88 0.35 2.84e-11 Schizophrenia; LIHC cis rs7106204 0.858 rs2403889 chr11:24210226 T/C ch.11.24196551F chr11:24239977 NA 0.76 10.13 0.48 2.98e-21 Response to Homoharringtonine (cytotoxicity); LIHC cis rs7131987 0.630 rs1006409 chr12:29435675 A/G cg14222432 chr12:29376421 FAR2 0.31 6.49 0.33 2.95e-10 QT interval; LIHC cis rs12477438 0.520 rs34252185 chr2:99737646 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs9457247 0.765 rs9295385 chr6:167448181 A/G cg23791538 chr6:167370224 RNASET2 -0.57 -8.0 -0.4 1.92e-14 Crohn's disease; LIHC cis rs4843747 0.749 rs13333619 chr16:88072076 C/T cg07527105 chr16:88053339 BANP -0.4 -5.75 -0.3 1.97e-8 Menopause (age at onset); LIHC cis rs12960505 0.506 rs1039452 chr18:50953078 C/T cg24270629 chr18:50823537 DCC -0.48 -6.72 -0.34 7.41e-11 Intelligence (multi-trait analysis); LIHC cis rs16828019 0.852 rs12044539 chr1:41661732 A/C cg03387723 chr1:41708464 SCMH1 -0.44 -7.13 -0.36 5.91e-12 Intelligence (multi-trait analysis); LIHC cis rs6540556 0.723 rs6672256 chr1:209894043 A/T cg05527609 chr1:210001259 C1orf107 0.53 6.86 0.35 3.23e-11 Red blood cell count; LIHC cis rs72781680 0.848 rs715646 chr2:24010566 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs2274273 0.870 rs7158768 chr14:55763612 A/C cg01864836 chr14:55583639 NA -0.39 -7.27 -0.37 2.51e-12 Protein biomarker; LIHC cis rs6088590 1.000 rs6087625 chr20:33342477 A/G cg06115741 chr20:33292138 TP53INP2 -0.62 -8.92 -0.43 2.89e-17 Coronary artery disease; LIHC cis rs7615952 0.576 rs2276729 chr3:125826214 G/A cg05084668 chr3:125655381 ALG1L -0.39 -6.13 -0.31 2.43e-9 Blood pressure (smoking interaction); LIHC cis rs2075371 0.933 rs2544201 chr7:133963561 C/G cg11752832 chr7:134001865 SLC35B4 0.51 7.92 0.39 3.35e-14 Mean platelet volume; LIHC trans rs4843747 0.697 rs72818533 chr16:88073841 G/A cg09572067 chr16:29127029 RRN3P2 0.57 8.61 0.42 2.77e-16 Menopause (age at onset); LIHC cis rs9556958 0.527 rs9517313 chr13:99105892 C/G cg20487152 chr13:99095054 FARP1 0.41 6.99 0.35 1.42e-11 Educational attainment (years of education); LIHC cis rs6088590 0.561 rs6088528 chr20:33156742 G/A cg08999081 chr20:33150536 PIGU 0.69 13.42 0.59 2.86e-33 Coronary artery disease; LIHC cis rs2072499 0.767 rs3001789 chr1:156197614 T/G cg24450063 chr1:156163899 SLC25A44 0.73 12.64 0.56 2.55e-30 Testicular germ cell tumor; LIHC cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg24642844 chr7:1081250 C7orf50 -0.65 -6.83 -0.35 3.99e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2354432 0.607 rs9782976 chr1:146825049 A/G cg25205988 chr1:146714368 CHD1L 0.9 12.82 0.57 5.22e-31 Mitochondrial DNA levels; LIHC cis rs908922 0.573 rs7544564 chr1:152527007 A/C cg20991723 chr1:152506922 NA 0.54 9.1 0.44 7.75e-18 Hair morphology; LIHC cis rs10463316 0.894 rs13357969 chr5:150751557 A/G cg03212797 chr5:150827313 SLC36A1 -0.47 -7.29 -0.37 2.17e-12 Metabolite levels (Pyroglutamine); LIHC cis rs11626933 1.000 rs6575122 chr14:90753556 A/G cg04374321 chr14:90722782 PSMC1 0.48 6.55 0.33 2.14e-10 Gut microbiota (bacterial taxa); LIHC cis rs59698941 0.943 rs12513758 chr5:132239939 C/G cg02081065 chr5:132209139 LEAP2 0.26 5.73 0.3 2.23e-8 Apolipoprotein A-IV levels; LIHC cis rs986417 0.688 rs8018111 chr14:60964347 A/G cg27398547 chr14:60952738 C14orf39 0.77 9.19 0.45 3.89e-18 Gut microbiota (bacterial taxa); LIHC cis rs6120849 0.754 rs6087667 chr20:33651887 A/G cg24642439 chr20:33292090 TP53INP2 0.66 7.2 0.36 3.8e-12 Protein C levels; LIHC cis rs12291225 0.679 rs7934671 chr11:14305101 C/T cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.11e-31 Sense of smell; LIHC cis rs881375 0.678 rs10985102 chr9:123707497 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.64 0.34 1.25e-10 Rheumatoid arthritis; LIHC cis rs17539620 0.624 rs871068 chr6:154837514 C/A cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs4388979 0.894 rs10850589 chr12:109499490 C/T cg03220751 chr12:109490328 USP30 0.87 13.09 0.58 5.04e-32 Plateletcrit;Platelet count; LIHC cis rs7592578 0.771 rs12052514 chr2:191378170 C/T cg10560079 chr2:191398806 TMEM194B -0.84 -12.28 -0.55 5.99e-29 Diastolic blood pressure; LIHC cis rs35150201 0.818 rs7810260 chr7:135311120 G/A cg23117316 chr7:135346802 PL-5283 -0.28 -5.85 -0.3 1.13e-8 Plateletcrit;Mean corpuscular hemoglobin;Mean platelet volume; LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg12311636 chr6:118886798 C6orf204 -0.53 -6.22 -0.32 1.44e-9 Diastolic blood pressure; LIHC cis rs3749237 0.576 rs62259939 chr3:49386047 G/A cg03060546 chr3:49711283 APEH 0.61 9.77 0.47 4.92e-20 Resting heart rate; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04237075 chr9:34637949 SIGMAR1 0.41 6.18 0.32 1.85e-9 Pancreatic cancer; LIHC cis rs4474465 1.000 rs873311 chr11:78145886 G/C cg27205649 chr11:78285834 NARS2 -0.4 -5.73 -0.3 2.2e-8 Alzheimer's disease (survival time); LIHC cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.07e-9 Developmental language disorder (linguistic errors); LIHC cis rs2292096 1.000 rs10494818 chr1:200749160 A/C cg11814564 chr1:200748674 CAMSAP1L1 -0.46 -6.17 -0.32 1.96e-9 Epilepsy; LIHC cis rs1878931 0.559 rs2106863 chr16:3391330 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.56 7.45 0.37 7.45e-13 Body mass index (adult); LIHC cis rs10791097 0.720 rs4936121 chr11:130733878 A/G cg12179176 chr11:130786555 SNX19 0.78 12.48 0.56 9.9e-30 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7647973 1.000 rs3870341 chr3:49584745 A/G cg07636037 chr3:49044803 WDR6 0.51 6.45 0.33 3.74e-10 Menarche (age at onset); LIHC cis rs7364180 0.515 rs6002503 chr22:42208672 A/G cg03806693 chr22:41940476 POLR3H -0.48 -6.46 -0.33 3.53e-10 Alzheimer's disease biomarkers; LIHC cis rs35110281 0.720 rs162374 chr21:44927089 T/C cg01579765 chr21:45077557 HSF2BP 0.34 6.23 0.32 1.39e-9 Mean corpuscular volume; LIHC cis rs8141529 0.753 rs5752813 chr22:29226570 T/G cg02153584 chr22:29168773 CCDC117 0.58 9.27 0.45 2.11e-18 Lymphocyte counts; LIHC cis rs6952808 0.609 rs4721190 chr7:1954732 A/G cg02951883 chr7:2050386 MAD1L1 0.57 8.59 0.42 3.12e-16 Bipolar disorder and schizophrenia; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.05 -0.31 3.78e-9 Total body bone mineral density; LIHC cis rs12893668 0.543 rs12147645 chr14:104100208 T/A cg24130564 chr14:104152367 KLC1 -0.55 -9.16 -0.44 4.73e-18 Reticulocyte count; LIHC cis rs9303401 0.614 rs28651036 chr17:57080471 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.41 0.56 1.91e-29 Cognitive test performance; LIHC cis rs651907 0.557 rs12629658 chr3:101356535 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 10.86 0.51 8.58e-24 Colorectal cancer; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg12648201 chr2:27665141 KRTCAP3 -0.42 -5.73 -0.3 2.19e-8 Total body bone mineral density; LIHC cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg05016508 chr11:63871570 FLRT1;MACROD1 0.43 5.91 0.3 8.32e-9 Platelet count; LIHC cis rs9916302 0.851 rs2338795 chr17:37399364 T/G cg03013999 chr17:37608204 MED1 0.35 5.9 0.3 8.82e-9 Glomerular filtration rate (creatinine); LIHC cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.25 0.45 2.4e-18 Bipolar disorder; LIHC cis rs4474465 0.850 rs7112872 chr11:78227396 C/A cg27205649 chr11:78285834 NARS2 0.39 5.96 0.31 6.31e-9 Alzheimer's disease (survival time); LIHC trans rs1920116 0.778 rs2421829 chr3:169554264 T/C cg00669760 chr2:44735195 C2orf34 0.38 6.05 0.31 3.79e-9 Glioma (high-grade); LIHC cis rs2180341 0.920 rs7756880 chr6:127683999 A/T cg24812749 chr6:127587940 RNF146 1.05 15.56 0.64 1.18e-41 Breast cancer; LIHC cis rs898097 0.578 rs6502021 chr17:80907728 T/C cg15664640 chr17:80829946 TBCD 0.45 7.46 0.37 7.34e-13 Breast cancer; LIHC cis rs736408 0.522 rs998909 chr3:52805093 A/G cg11645453 chr3:52864694 ITIH4 0.22 5.96 0.31 6.38e-9 Bipolar disorder; LIHC cis rs9581857 0.512 rs9581866 chr13:28063176 G/A cg22138327 chr13:27999177 GTF3A 0.75 5.89 0.3 9.31e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC trans rs11098499 0.754 rs12506610 chr4:120241659 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs4650994 0.593 rs2811297 chr1:178551472 C/T cg05350800 chr1:178550844 NA -0.31 -6.89 -0.35 2.77e-11 HDL cholesterol levels;HDL cholesterol; LIHC cis rs918629 0.761 rs10073752 chr5:95279233 A/C cg10483112 chr5:95245456 ELL2 -0.36 -6.1 -0.31 2.85e-9 IgG glycosylation; LIHC cis rs9457247 1.000 rs376551 chr6:167384923 G/A cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg26119090 chr2:26468346 HADHA;HADHB -1.1 -17.18 -0.68 3.93e-48 Gut microbiome composition (summer); LIHC cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg07092213 chr7:1199455 ZFAND2A -0.42 -6.23 -0.32 1.36e-9 Longevity;Endometriosis; LIHC cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.77 -0.5 1.68e-23 Platelet count; LIHC cis rs17106184 0.892 rs111701702 chr1:51284446 T/C cg07174182 chr1:51127561 FAF1 -0.65 -7.17 -0.36 4.69e-12 Type 2 diabetes; LIHC cis rs7772486 0.686 rs6570705 chr6:145961201 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.64 0.53 1.27e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs1775715 0.870 rs1775735 chr10:32255846 A/G cg14930904 chr10:32216787 ARHGAP12 0.4 7.07 0.36 8.68e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9814567 0.727 rs9809344 chr3:134342758 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.55 -8.84 -0.43 5.16e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.11 10.63 0.5 5.46e-23 Platelet count; LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.97 0.8 4.54e-79 Prudent dietary pattern; LIHC cis rs332507 0.830 rs11714527 chr3:124422722 G/A cg05980111 chr3:124395277 KALRN 0.42 6.53 0.33 2.44e-10 Plateletcrit; LIHC cis rs6952808 0.792 rs11771973 chr7:1950440 C/G cg04267008 chr7:1944627 MAD1L1 -0.71 -11.32 -0.52 1.95e-25 Bipolar disorder and schizophrenia; LIHC cis rs7572733 0.534 rs700682 chr2:198712310 C/A cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg25894440 chr7:65020034 NA 0.54 6.25 0.32 1.23e-9 Diabetic kidney disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09774412 chr22:50902130 SBF1 0.43 6.28 0.32 1.04e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4891159 0.790 rs17059379 chr18:74160316 A/T cg24786174 chr18:74118243 ZNF516 0.7 12.63 0.56 2.87e-30 Longevity; LIHC cis rs4561483 0.545 rs9927446 chr16:11957164 A/T cg08843971 chr16:11963173 GSPT1 0.38 7.2 0.36 3.94e-12 Testicular germ cell tumor; LIHC cis rs981946 0.544 rs10498660 chr6:3343544 C/T cg18842474 chr6:3356384 SLC22A23 0.36 5.8 0.3 1.5e-8 Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN); LIHC cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg20295408 chr7:1910781 MAD1L1 -0.4 -5.83 -0.3 1.3e-8 Bipolar disorder and schizophrenia; LIHC cis rs785830 0.717 rs617453 chr9:223339 A/G cg14500300 chr9:211689 NA 0.29 6.7 0.34 8.67e-11 Platelet distribution width; LIHC cis rs2235642 0.821 rs2281234 chr16:1602938 A/G cg03034668 chr16:1723424 CRAMP1L -0.41 -7.29 -0.37 2.21e-12 Coronary artery disease; LIHC cis rs7107174 1.000 rs2511158 chr11:77973980 C/T cg02023728 chr11:77925099 USP35 0.5 9.39 0.45 8.76e-19 Testicular germ cell tumor; LIHC cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg17971929 chr21:40555470 PSMG1 -0.46 -7.12 -0.36 6.59e-12 Cognitive function; LIHC cis rs2228479 0.850 rs11649162 chr16:89807131 C/A cg06558623 chr16:89946397 TCF25 0.87 11.88 0.54 1.69e-27 Skin colour saturation; LIHC cis rs1003719 1.000 rs2835607 chr21:38491973 T/G cg10648535 chr21:38446584 PIGP;TTC3 0.74 11.24 0.52 3.75e-25 Eye color traits; LIHC cis rs10779751 0.770 rs11121691 chr1:11181327 C/T cg08854313 chr1:11322531 MTOR -0.77 -9.82 -0.47 3.38e-20 Body mass index; LIHC cis rs6831352 0.918 rs34876213 chr4:100062216 G/A cg12011299 chr4:100065546 ADH4 -0.62 -10.39 -0.49 3.69e-22 Alcohol dependence; LIHC cis rs9303401 0.614 rs7215900 chr17:56654850 A/T cg25039879 chr17:56429692 SUPT4H1 0.76 8.29 0.41 2.66e-15 Cognitive test performance; LIHC trans rs11098499 0.954 rs7681544 chr4:120411255 T/C cg25214090 chr10:38739885 LOC399744 0.57 9.44 0.45 6.19e-19 Corneal astigmatism; LIHC cis rs12594515 0.967 rs11854477 chr15:45998345 A/C cg01629716 chr15:45996671 NA 0.51 9.12 0.44 6.75e-18 Waist circumference;Weight; LIHC trans rs4596713 0.538 rs10781456 chr9:71782869 G/A cg16512924 chr15:28394682 HERC2 0.39 6.26 0.32 1.18e-9 Headache; LIHC cis rs7091068 0.616 rs7920366 chr10:95497178 A/T cg20715218 chr10:95462985 C10orf4 0.59 6.15 0.32 2.22e-9 Urinary tract infection frequency; LIHC cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg21782813 chr7:2030301 MAD1L1 0.49 8.68 0.42 1.62e-16 Bipolar disorder and schizophrenia; LIHC cis rs2370759 1.000 rs2370759 chr10:32634972 G/A cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs34172651 0.917 rs35283675 chr16:24820393 A/G cg00339695 chr16:24857497 SLC5A11 0.53 7.98 0.4 2.31e-14 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07147234 chr12:56522077 ESYT1 0.43 6.09 0.31 3.05e-9 Pancreatic cancer; LIHC cis rs875971 0.862 rs3926380 chr7:66080645 G/T cg18252515 chr7:66147081 NA 0.45 6.56 0.33 1.97e-10 Aortic root size; LIHC cis rs2404602 0.716 rs8025134 chr15:76781729 C/T cg03037974 chr15:76606532 NA 0.78 15.94 0.65 3.71e-43 Blood metabolite levels; LIHC cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg23172400 chr8:95962367 TP53INP1 -0.36 -7.93 -0.39 3.22e-14 Type 2 diabetes; LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs1008375 1.000 rs4698200 chr4:17657051 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.83 0.3 1.29e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg26939375 chr7:64535504 NA 0.47 7.17 0.36 4.73e-12 Aortic root size; LIHC cis rs5769765 0.773 rs138861 chr22:50202276 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.68 -8.03 -0.4 1.64e-14 Schizophrenia; LIHC cis rs10876993 0.890 rs2640630 chr12:58067267 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.26 -0.32 1.17e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg18713687 chr3:195489789 MUC4 -0.67 -10.07 -0.48 4.72e-21 Lung disease severity in cystic fibrosis; LIHC cis rs1799949 0.965 rs7212284 chr17:41205941 A/G cg25072359 chr17:41440525 NA 0.39 6.28 0.32 1.02e-9 Menopause (age at onset); LIHC cis rs4820294 1.000 rs62236665 chr22:38059847 C/A cg00142150 chr22:38071001 LGALS1 0.7 11.36 0.52 1.42e-25 Fat distribution (HIV); LIHC cis rs10857712 0.551 rs12252576 chr10:135227244 T/C cg15472797 chr10:135243109 NA -0.4 -6.59 -0.34 1.63e-10 Systemic lupus erythematosus; LIHC cis rs6998277 1.000 rs4734648 chr8:103635994 G/A cg10187029 chr8:103597600 NA 0.71 8.9 0.43 3.28e-17 Migraine; LIHC cis rs9303401 0.659 rs12150536 chr17:56640834 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.93 12.34 0.56 3.48e-29 Cognitive test performance; LIHC cis rs651907 0.535 rs61396602 chr3:101509046 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.06 0.48 5.15e-21 Colorectal cancer; LIHC cis rs921968 0.541 rs7574429 chr2:219498759 T/G cg02176678 chr2:219576539 TTLL4 0.55 7.49 0.38 6.01e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7429990 0.901 rs6442102 chr3:48152562 A/G cg11946769 chr3:48343235 NME6 -0.48 -6.41 -0.33 4.81e-10 Educational attainment (years of education); LIHC cis rs2531992 1.000 rs2531992 chr16:4021734 A/G cg05927578 chr16:4029543 ADCY9 0.58 6.81 0.35 4.31e-11 Waist circumference; LIHC trans rs62103177 0.525 rs4799116 chr18:77736735 A/G cg05926928 chr17:57297772 GDPD1 -0.62 -6.98 -0.35 1.53e-11 Opioid sensitivity; LIHC cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg02290350 chr8:58132656 NA 0.42 8.78 0.43 7.73e-17 Developmental language disorder (linguistic errors); LIHC cis rs77633900 0.614 rs2439991 chr15:76877227 A/G cg21673338 chr15:77095150 SCAPER -0.5 -7.24 -0.36 2.93e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs1892700 0.764 rs1804385 chr21:34896962 C/G cg14850771 chr21:34775459 IFNGR2 -0.46 -6.15 -0.32 2.11e-9 Educational attainment; LIHC cis rs5758511 0.508 rs2413667 chr22:42472237 A/C cg00645731 chr22:42541494 CYP2D7P1 0.57 5.77 0.3 1.81e-8 Birth weight; LIHC cis rs7843479 0.965 rs17616085 chr8:21857267 C/T cg17168535 chr8:21777572 XPO7 0.37 6.22 0.32 1.49e-9 Mean corpuscular volume; LIHC cis rs965469 1.000 rs2236123 chr20:3305305 C/G cg25506879 chr20:3388711 C20orf194 0.51 5.84 0.3 1.23e-8 IFN-related cytopenia; LIHC cis rs769267 0.965 rs2916068 chr19:19516433 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.13 0.31 2.43e-9 Tonsillectomy; LIHC cis rs614226 0.935 rs77955762 chr12:121009948 T/C cg01236616 chr12:121019343 POP5 -1.32 -17.01 -0.68 1.81e-47 Type 1 diabetes nephropathy; LIHC cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg03806693 chr22:41940476 POLR3H 1.06 12.64 0.56 2.63e-30 Vitiligo; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg22481253 chr6:34204911 HMGA1 0.45 6.35 0.32 6.96e-10 Triglycerides; LIHC cis rs2806561 0.577 rs488438 chr1:23498999 T/A cg12483005 chr1:23474871 LUZP1 0.47 7.37 0.37 1.31e-12 Height; LIHC cis rs4906332 1.000 rs28711288 chr14:103906126 T/C cg26031613 chr14:104095156 KLC1 -0.4 -5.83 -0.3 1.26e-8 Coronary artery disease; LIHC cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg03264133 chr6:25882463 NA -0.47 -7.2 -0.36 3.77e-12 Height; LIHC cis rs986417 0.748 rs11158289 chr14:61032390 C/T cg27398547 chr14:60952738 C14orf39 0.57 7.05 0.36 9.75e-12 Gut microbiota (bacterial taxa); LIHC cis rs7772486 0.790 rs4314514 chr6:146260010 A/G cg13319975 chr6:146136371 FBXO30 0.35 5.72 0.3 2.27e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7833790 0.660 rs7839178 chr8:82763479 A/G cg27398817 chr8:82754497 SNX16 0.32 5.77 0.3 1.77e-8 Diastolic blood pressure; LIHC cis rs4906332 1.000 rs55930273 chr14:103960298 G/A cg04998671 chr14:104000505 TRMT61A -0.46 -6.26 -0.32 1.17e-9 Coronary artery disease; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg02902477 chr6:26197071 HIST1H3D 0.53 5.87 0.3 1.01e-8 Gout;Renal underexcretion gout; LIHC cis rs1707322 0.721 rs7519900 chr1:46234947 C/T cg03146154 chr1:46216737 IPP 0.58 9.76 0.47 5.19e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4979906 1.000 rs7923587 chr10:79453218 C/T cg07817648 chr10:79422355 NA 0.29 6.33 0.32 7.81e-10 Mortality in heart failure; LIHC cis rs72627509 0.857 rs781658 chr4:57779567 G/A cg26694713 chr4:57773883 REST 0.73 10.46 0.49 2.09e-22 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg12310025 chr6:25882481 NA 0.6 8.48 0.42 6.68e-16 Blood metabolite levels; LIHC cis rs739401 0.572 rs384490 chr11:3078885 A/C cg08508325 chr11:3079039 CARS -0.35 -7.7 -0.38 1.45e-13 Longevity; LIHC cis rs11122272 0.735 rs2244986 chr1:231537452 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -10.54 -0.5 1.08e-22 Hemoglobin concentration; LIHC trans rs9388451 0.839 rs3799711 chr6:126075313 C/T cg27561452 chr16:68573240 ZFP90 0.42 6.34 0.32 7.29e-10 Brugada syndrome; LIHC cis rs10818894 0.772 rs10120705 chr9:126692600 T/G cg16191174 chr9:126692580 DENND1A 0.62 7.08 0.36 8.11e-12 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); LIHC cis rs1144333 0.510 rs12408897 chr1:76448102 T/C cg03433033 chr1:76189801 ACADM 0.54 7.46 0.37 7.27e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs10779751 1.000 rs2300093 chr1:11266392 G/C cg08854313 chr1:11322531 MTOR 0.86 15.56 0.64 1.14e-41 Body mass index; LIHC cis rs74181299 0.533 rs12713533 chr2:65364702 G/T cg05010058 chr2:65284262 CEP68 -0.37 -5.94 -0.31 6.83e-9 Pulse pressure; LIHC cis rs10876993 0.855 rs1689601 chr12:58049557 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.79 -0.34 5.05e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs4713118 0.513 rs1225591 chr6:28148752 G/A cg23485639 chr6:28045615 ZNF165 0.39 6.11 0.31 2.72e-9 Parkinson's disease; LIHC cis rs3741404 0.868 rs595880 chr11:64006466 T/G cg18225595 chr11:63971243 STIP1 -0.64 -9.7 -0.46 8.27e-20 Platelet count; LIHC cis rs17102423 0.755 rs7143495 chr14:65546361 C/T cg11161011 chr14:65562177 MAX 0.56 8.16 0.4 6.33e-15 Obesity-related traits; LIHC cis rs757081 0.667 rs17561348 chr11:17161615 C/T cg15432903 chr11:17409602 KCNJ11 0.41 5.78 0.3 1.67e-8 Systolic blood pressure; LIHC cis rs11229555 0.645 rs11229442 chr11:58196790 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg22481606 chr17:56429567 SUPT4H1 -0.47 -6.09 -0.31 2.98e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg12310025 chr6:25882481 NA -0.7 -9.32 -0.45 1.49e-18 Intelligence (multi-trait analysis); LIHC cis rs4975709 0.589 rs4975747 chr5:1862836 G/A cg15595755 chr5:1867978 NA 0.4 8.04 0.4 1.49e-14 Cardiovascular disease risk factors; LIHC cis rs7212590 0.618 rs7217337 chr17:58023417 C/T cg10252138 chr17:58120427 NA -0.58 -5.91 -0.3 8.12e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs722599 0.683 rs8014695 chr14:75301617 C/G cg08847533 chr14:75593920 NEK9 0.54 8.35 0.41 1.67e-15 IgG glycosylation; LIHC cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg03452623 chr4:187889614 NA -0.34 -8.83 -0.43 5.38e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769765 0.773 rs9616206 chr22:50310847 G/T cg02269571 chr22:50332266 NA -0.74 -9.75 -0.47 5.47e-20 Schizophrenia; LIHC cis rs17376456 0.877 rs10065056 chr5:93380123 G/T cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs6429082 0.818 rs291381 chr1:235641924 A/G cg26050004 chr1:235667680 B3GALNT2 0.51 7.94 0.39 2.95e-14 Adiposity; LIHC cis rs17376456 0.569 rs7729807 chr5:93104089 C/T cg25358565 chr5:93447407 FAM172A 0.8 7.68 0.38 1.63e-13 Diabetic retinopathy; LIHC cis rs1577917 0.837 rs10944157 chr6:86577199 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -7.81 -0.39 7.04e-14 Response to antipsychotic treatment; LIHC cis rs7264396 0.623 rs2425123 chr20:34329547 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.74 -0.43 1.1e-16 Total cholesterol levels; LIHC cis rs7927771 1.000 rs4752873 chr11:47857520 C/T cg20307385 chr11:47447363 PSMC3 -0.45 -5.85 -0.3 1.18e-8 Subjective well-being; LIHC cis rs801193 0.773 rs801207 chr7:66020590 T/C cg11764359 chr7:65958608 NA -0.62 -9.49 -0.46 4.18e-19 Aortic root size; LIHC cis rs651907 0.557 rs3806654 chr3:101396529 G/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.7 11.8 0.54 3.45e-27 Colorectal cancer; LIHC cis rs858239 0.537 rs6955115 chr7:23227144 A/G cg18081818 chr7:23246105 NA -0.4 -5.93 -0.31 7.36e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2075371 0.863 rs2075370 chr7:133967812 A/G cg20476274 chr7:133979776 SLC35B4 0.73 12.61 0.56 3.21e-30 Mean platelet volume; LIHC cis rs1355223 0.583 rs2915179 chr11:34871943 C/T cg24088639 chr11:34937564 PDHX;APIP -0.39 -5.99 -0.31 5.17e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs2749592 0.513 rs9417249 chr10:37837155 C/T cg17830980 chr10:43048298 ZNF37B 0.34 6.27 0.32 1.07e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9314323 0.862 rs3808580 chr8:26250296 C/T cg13160058 chr8:26243215 BNIP3L 0.43 8.06 0.4 1.28e-14 Red cell distribution width; LIHC cis rs7833790 1.000 rs7833790 chr8:82731157 T/C cg02079420 chr8:82753780 SNX16 0.34 5.86 0.3 1.06e-8 Diastolic blood pressure; LIHC cis rs796364 0.806 rs79053279 chr2:201057443 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.77 -8.04 -0.4 1.45e-14 Schizophrenia; LIHC cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg07424592 chr7:64974309 NA -0.8 -9.29 -0.45 1.82e-18 Diabetic kidney disease; LIHC cis rs6665290 0.904 rs1343743 chr1:227183125 C/T cg10327440 chr1:227177885 CDC42BPA -1.18 -26.78 -0.82 6.04e-86 Myeloid white cell count; LIHC cis rs7312933 1.000 rs11181308 chr12:42445259 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.83 0.35 3.91e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs870825 0.616 rs4623060 chr4:185642943 A/G cg04058563 chr4:185651563 MLF1IP 0.77 7.79 0.39 8.15e-14 Blood protein levels; LIHC cis rs748404 0.578 rs573615 chr15:43614281 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.59 10.53 0.49 1.2e-22 Lung cancer; LIHC cis rs1005277 0.579 rs2505237 chr10:38438898 T/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs4423214 1.000 rs7928249 chr11:71161063 A/G cg24826892 chr11:71159390 DHCR7 0.5 6.48 0.33 3.15e-10 Vitamin D levels; LIHC cis rs757110 0.745 rs2074311 chr11:17421860 A/G cg15432903 chr11:17409602 KCNJ11 0.52 8.01 0.4 1.83e-14 Type 2 diabetes; LIHC cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs2230307 0.536 rs11166385 chr1:100443462 A/G cg24955406 chr1:100503596 HIAT1 0.6 6.01 0.31 4.64e-9 Carotid intima media thickness; LIHC cis rs7208859 0.573 rs8064686 chr17:29134839 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.18 0.4 5.73e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06942197 chr17:38804076 SMARCE1 -0.48 -6.77 -0.34 5.57e-11 Pancreatic cancer; LIHC cis rs6754311 0.552 rs1030765 chr2:136553188 A/T cg17750252 chr2:136567154 LCT 0.35 6.0 0.31 5.07e-9 Mosquito bite size; LIHC cis rs4243830 0.850 rs12563717 chr1:6599557 T/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.88 9.68 0.46 9.36e-20 Body mass index; LIHC cis rs8072100 0.870 rs10432035 chr17:45624913 G/C cg08085267 chr17:45401833 C17orf57 0.4 5.97 0.31 5.9e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs858239 0.932 rs1637190 chr7:23269065 A/G cg18081818 chr7:23246105 NA -0.39 -5.99 -0.31 5.35e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg06558623 chr16:89946397 TCF25 0.96 15.09 0.63 8.93e-40 Skin colour saturation; LIHC cis rs12188164 0.525 rs2561665 chr5:460135 A/G cg08916839 chr5:415575 AHRR 0.29 6.18 0.32 1.87e-9 Cystic fibrosis severity; LIHC cis rs2576037 0.526 rs2576051 chr18:44557884 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.47 6.83 0.35 3.94e-11 Personality dimensions; LIHC cis rs13392177 0.684 rs6720449 chr2:219080978 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.56 -7.9 -0.39 3.88e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg05590025 chr7:65112418 INTS4L2 -0.58 -6.42 -0.33 4.57e-10 Diabetic kidney disease; LIHC cis rs892961 0.932 rs35657663 chr17:75412482 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC trans rs1005277 0.579 rs9418322 chr10:38377296 G/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs5769765 1.000 rs768618 chr22:50286827 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.15 -0.44 5.07e-18 Schizophrenia; LIHC cis rs9916302 0.851 rs11078907 chr17:37662954 C/T cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC trans rs1814175 0.817 rs28502006 chr11:50049930 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.41e-11 Height; LIHC cis rs1371867 0.875 rs1619759 chr8:101337560 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -8.72 -0.43 1.2e-16 Atrioventricular conduction; LIHC cis rs2073499 0.935 rs74398439 chr3:50331927 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 0.71 8.11 0.4 8.94e-15 Schizophrenia; LIHC cis rs3806843 0.808 rs6893708 chr5:140125922 T/C cg19875535 chr5:140030758 IK -0.36 -5.88 -0.3 9.63e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs561341 0.714 rs111760509 chr17:30304320 A/G cg00745463 chr17:30367425 LRRC37B -0.77 -5.72 -0.3 2.35e-8 Hip circumference adjusted for BMI; LIHC cis rs2242116 0.932 rs7646906 chr3:46949379 G/A cg02527881 chr3:46936655 PTH1R -0.5 -10.73 -0.5 2.4e-23 Birth weight; LIHC cis rs12477438 0.520 rs11123766 chr2:99780915 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.35 0.77 7.7e-69 Chronic sinus infection; LIHC cis rs801193 0.773 rs801207 chr7:66020590 T/C cg18876405 chr7:65276391 NA -0.4 -7.3 -0.37 2.08e-12 Aortic root size; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg12376772 chr13:32526694 EEF1DP3 0.63 6.55 0.33 2.09e-10 Mean platelet volume; LIHC cis rs11098499 0.708 rs1546506 chr4:120241240 T/C cg09307838 chr4:120376055 NA 0.71 11.17 0.52 6.58e-25 Corneal astigmatism; LIHC cis rs798554 0.797 rs798486 chr7:2803037 A/G cg19346786 chr7:2764209 NA -0.47 -7.09 -0.36 7.77e-12 Height; LIHC cis rs7777754 0.512 rs4470989 chr7:50562698 T/A cg14593290 chr7:50529359 DDC -0.46 -7.44 -0.37 8.02e-13 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC cis rs8180040 0.764 rs4683324 chr3:47251284 T/C cg27129171 chr3:47204927 SETD2 0.7 12.35 0.56 3.04e-29 Colorectal cancer; LIHC cis rs782590 0.774 rs782637 chr2:55894247 T/C cg03859395 chr2:55845619 SMEK2 0.78 13.22 0.58 1.57e-32 Metabolic syndrome; LIHC cis rs763014 0.966 rs4984903 chr16:680695 A/G cg04709771 chr16:646395 RAB40C 0.47 8.3 0.41 2.44e-15 Height; LIHC trans rs1814175 0.791 rs1722011 chr11:49899340 G/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC trans rs1005277 0.522 rs289649 chr10:37975384 T/C cg27523141 chr10:43048294 ZNF37B 0.38 6.53 0.33 2.43e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2404602 0.716 rs8039545 chr15:76707247 A/G cg23625390 chr15:77176239 SCAPER 0.36 6.0 0.31 5.07e-9 Blood metabolite levels; LIHC cis rs7395581 0.918 rs3781622 chr11:47348702 T/C cg25783544 chr11:47291846 MADD 0.41 5.82 0.3 1.33e-8 HDL cholesterol; LIHC cis rs7267979 0.932 rs449370 chr20:25451180 A/G cg24626310 chr20:25276739 ABHD12;PYGB -0.47 -6.88 -0.35 2.95e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs34172651 0.917 rs200532 chr16:24756148 C/T cg00339695 chr16:24857497 SLC5A11 -0.32 -5.75 -0.3 2.03e-8 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg20887711 chr4:1340912 KIAA1530 -0.48 -7.45 -0.37 7.76e-13 Obesity-related traits; LIHC cis rs17685 0.712 rs1637049 chr7:75729975 C/G cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.75e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1801251 0.893 rs6733151 chr2:233592341 A/C cg08000102 chr2:233561755 GIGYF2 0.77 11.52 0.53 3.61e-26 Coronary artery disease; LIHC cis rs2067615 0.579 rs10778509 chr12:107162918 G/A cg15890332 chr12:107067104 RFX4 0.27 6.25 0.32 1.21e-9 Heart rate; LIHC cis rs4631830 0.863 rs6481329 chr10:51529746 G/A cg20129853 chr10:51489980 NA -0.41 -8.96 -0.44 2.13e-17 Prostate-specific antigen levels; LIHC cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg12311346 chr5:56204834 C5orf35 0.67 8.61 0.42 2.62e-16 Initial pursuit acceleration; LIHC cis rs2153535 0.580 rs7743686 chr6:8526111 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.72 0.54 6.76e-27 Motion sickness; LIHC cis rs11711311 1.000 rs2242109 chr3:113434100 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.06 -0.36 9.18e-12 IgG glycosylation; LIHC cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg06634786 chr22:41940651 POLR3H -0.76 -7.9 -0.39 3.86e-14 Vitiligo; LIHC cis rs4665809 0.816 rs2384359 chr2:26371364 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.83 -10.4 -0.49 3.41e-22 Gut microbiome composition (summer); LIHC trans rs1814175 0.817 rs4881623 chr11:49804991 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.85 0.35 3.39e-11 Height; LIHC cis rs240764 0.817 rs239249 chr6:101087081 G/A cg09795085 chr6:101329169 ASCC3 0.51 7.19 0.36 4.11e-12 Neuroticism; LIHC cis rs11122272 0.735 rs2808596 chr1:231530723 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.34 0.45 1.22e-18 Hemoglobin concentration; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.96 0.54 8.7300000000000009e-28 Prudent dietary pattern; LIHC cis rs12995491 0.731 rs34991383 chr2:88500337 T/G cg04511125 chr2:88470314 THNSL2 -0.47 -6.94 -0.35 2e-11 Response to metformin (IC50); LIHC cis rs921968 0.565 rs13412324 chr2:219620521 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7312933 0.558 rs11181466 chr12:42765181 A/T cg17420585 chr12:42539391 GXYLT1 -0.36 -5.91 -0.3 8.19e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9388451 0.874 rs13209968 chr6:126089285 G/C cg06289844 chr6:126071538 HEY2 0.38 6.62 0.34 1.42e-10 Brugada syndrome; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg18538332 chr22:24372958 LOC391322 -0.59 -8.32 -0.41 2.15e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7107174 0.901 rs7941639 chr11:78116959 A/G cg02023728 chr11:77925099 USP35 -0.41 -7.45 -0.37 7.78e-13 Testicular germ cell tumor; LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg08219700 chr8:58056026 NA 0.52 7.15 0.36 5.24e-12 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg21782813 chr7:2030301 MAD1L1 0.54 9.98 0.47 9.5e-21 Bipolar disorder and schizophrenia; LIHC trans rs3742264 0.656 rs6561275 chr13:46518299 A/T cg08762273 chr6:26247270 HIST1H4G 0.3 6.04 0.31 4.08e-9 Blood protein levels; LIHC cis rs10131894 0.635 rs174997 chr14:75434806 G/A cg11812906 chr14:75593930 NEK9 -0.65 -11.57 -0.53 2.47e-26 Coronary artery disease; LIHC cis rs7412746 0.611 rs752376 chr1:150941381 C/T cg17724175 chr1:150552817 MCL1 0.38 7.45 0.37 7.66e-13 Melanoma; LIHC cis rs1801251 0.656 rs10211596 chr2:233699415 C/T cg08000102 chr2:233561755 GIGYF2 -0.75 -12.24 -0.55 8.19e-29 Coronary artery disease; LIHC cis rs7651039 0.619 rs7640807 chr3:15685137 A/G cg16303742 chr3:15540471 COLQ 0.52 9.44 0.45 6.17e-19 Coronary heart disease; LIHC cis rs11822910 0.871 rs2581928 chr11:57202790 A/G cg00522883 chr11:57194120 SLC43A3 -0.67 -8.89 -0.43 3.61e-17 Platelet distribution width; LIHC cis rs992157 0.764 rs2015863 chr2:219185161 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.68 -9.55 -0.46 2.56e-19 Colorectal cancer; LIHC cis rs6747952 0.899 rs2121404 chr2:239083826 A/G cg17459225 chr2:239074497 NA 0.37 5.93 0.31 7.42e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs6430585 0.583 rs7561565 chr2:136640787 A/C cg07169764 chr2:136633963 MCM6 1.3 23.54 0.79 1.63e-73 Corneal structure; LIHC cis rs782590 0.643 rs13032503 chr2:55739093 C/T cg18811423 chr2:55921094 PNPT1 -0.53 -8.0 -0.4 2e-14 Metabolic syndrome; LIHC trans rs61931739 0.534 rs1486886 chr12:34043619 C/T cg26384229 chr12:38710491 ALG10B 0.45 6.41 0.33 4.71e-10 Morning vs. evening chronotype; LIHC cis rs7927771 0.524 rs10838739 chr11:47672743 A/G cg20307385 chr11:47447363 PSMC3 -0.75 -11.19 -0.52 5.54e-25 Subjective well-being; LIHC trans rs1814175 0.645 rs28634872 chr11:50042175 T/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.23 0.41 4.09e-15 Platelet count; LIHC cis rs6061231 1.000 rs11908473 chr20:60957770 C/G cg03945807 chr20:60948434 NA 0.4 6.5 0.33 2.86e-10 Colorectal cancer; LIHC cis rs55665837 1.000 rs12287715 chr11:14444575 G/A cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs9929218 0.906 rs9933844 chr16:68747001 G/A cg01231543 chr16:68741748 NA 0.39 6.02 0.31 4.51e-9 Colorectal cancer; LIHC cis rs6964587 0.692 rs418 chr7:91583334 C/T cg17063962 chr7:91808500 NA -0.64 -11.26 -0.52 3.11e-25 Breast cancer; LIHC cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg27297192 chr10:134578999 INPP5A 0.51 6.88 0.35 2.86e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2839186 0.559 rs2277826 chr21:47639492 C/G cg12379764 chr21:47803548 PCNT 0.56 8.12 0.4 8.31e-15 Testicular germ cell tumor; LIHC cis rs763121 0.752 rs6001190 chr22:39073811 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.27 0.52 2.88e-25 Menopause (age at onset); LIHC cis rs546131 0.890 rs496558 chr11:34826425 C/T cg11058730 chr11:34937778 PDHX;APIP 0.6 9.06 0.44 1e-17 Lung disease severity in cystic fibrosis; LIHC cis rs3540 0.554 rs113942266 chr15:91072990 A/G cg22089800 chr15:90895588 ZNF774 -0.53 -7.46 -0.37 7.12e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs10838687 0.800 rs2290146 chr11:47353498 G/A cg26139080 chr11:47293733 MADD -0.41 -5.73 -0.3 2.19e-8 Proinsulin levels; LIHC cis rs10911232 0.507 rs10732271 chr1:183025898 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.55 0.5 1e-22 Hypertriglyceridemia; LIHC cis rs10791323 0.569 rs10750542 chr11:133713436 T/C cg06766960 chr11:133703094 NA -0.66 -11.05 -0.51 1.73e-24 Childhood ear infection; LIHC cis rs250677 0.687 rs40149 chr5:148444275 A/T cg18129178 chr5:148520854 ABLIM3 -0.48 -7.46 -0.37 7.3e-13 Breast cancer; LIHC cis rs2549003 1.000 rs2070724 chr5:131822072 A/G cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs360798 0.512 rs7562149 chr2:63008414 A/G cg17519650 chr2:63277830 OTX1 -0.42 -6.69 -0.34 9.2e-11 Coronary artery disease; LIHC cis rs911119 0.913 rs6048928 chr20:23585988 A/G cg16589663 chr20:23618590 CST3 0.72 7.58 0.38 3.35e-13 Chronic kidney disease; LIHC cis rs116248771 0.739 rs73156428 chr3:158346471 T/C cg16708174 chr3:158430962 RARRES1 0.47 6.26 0.32 1.14e-9 diarrhoeal disease at age 2; LIHC cis rs317689 0.718 rs645026 chr12:69757931 G/A cg22834771 chr12:69754056 YEATS4 -0.38 -5.84 -0.3 1.22e-8 Response to diuretic therapy; LIHC cis rs4888262 0.526 rs4887777 chr16:74637821 A/G cg01733217 chr16:74700730 RFWD3 0.83 16.3 0.66 1.31e-44 Testicular germ cell tumor; LIHC cis rs7208859 0.524 rs73263982 chr17:28920624 T/C cg13385521 chr17:29058706 SUZ12P 0.58 5.8 0.3 1.54e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6598955 0.671 rs17163866 chr1:26648088 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.71 -7.18 -0.36 4.42e-12 Obesity-related traits; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg26338869 chr17:61819248 STRADA 0.61 8.65 0.42 2e-16 Prudent dietary pattern; LIHC cis rs4595586 0.525 rs11612680 chr12:39344443 A/G cg26384229 chr12:38710491 ALG10B 0.53 6.35 0.32 6.99e-10 Morning vs. evening chronotype; LIHC cis rs2070433 0.539 rs2839314 chr21:47961067 A/G cg12379764 chr21:47803548 PCNT 0.64 9.92 0.47 1.55e-20 Lymphocyte counts; LIHC cis rs2737618 0.651 rs2816976 chr1:200081021 A/T cg21825944 chr1:200113062 NR5A2 -0.46 -7.95 -0.4 2.67e-14 Uric acid levels; LIHC cis rs7098414 0.511 rs4934134 chr10:82160582 C/T cg00277334 chr10:82204260 NA -0.61 -9.99 -0.48 8.77e-21 Post bronchodilator FEV1; LIHC cis rs6570726 0.577 rs9497315 chr6:145791967 C/T cg13319975 chr6:146136371 FBXO30 0.59 8.62 0.42 2.54e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 0.718 rs6774635 chr3:160847908 A/G cg03342759 chr3:160939853 NMD3 -0.68 -8.31 -0.41 2.25e-15 Morning vs. evening chronotype; LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg24209194 chr3:40518798 ZNF619 0.64 9.7 0.46 8.44e-20 Renal cell carcinoma; LIHC cis rs1003719 0.788 rs3787783 chr21:38462959 T/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs10751667 1.000 rs7395691 chr11:985006 T/C cg06064525 chr11:970664 AP2A2 -0.49 -12.08 -0.55 3.32e-28 Alzheimer's disease (late onset); LIHC cis rs10845606 0.560 rs7973428 chr12:12828050 C/T cg09462578 chr12:12878428 APOLD1 -0.42 -6.11 -0.31 2.7e-9 Systemic lupus erythematosus; LIHC cis rs3741798 1.000 rs3825259 chr12:12496635 A/G cg08615371 chr12:12503544 MANSC1 0.9 7.31 0.37 1.85e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg16145915 chr7:1198662 ZFAND2A -0.41 -11.18 -0.52 6.23e-25 Longevity;Endometriosis; LIHC cis rs9733 0.596 rs72702556 chr1:150680115 C/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs11971779 0.616 rs7779314 chr7:139112696 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.29 0.49 8.39e-22 Diisocyanate-induced asthma; LIHC trans rs73198271 0.515 rs17629935 chr8:8619381 A/T cg06710121 chr8:12235606 FAM66A 0.63 6.23 0.32 1.35e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs1005277 0.522 rs289650 chr10:37975505 G/T cg27523141 chr10:43048294 ZNF37B 0.36 6.68 0.34 9.72e-11 Extrinsic epigenetic age acceleration; LIHC cis rs17776563 0.853 rs72763825 chr15:89149872 A/G cg05013243 chr15:89149849 MIR1179 0.42 6.81 0.35 4.5e-11 Thyroid hormone levels; LIHC cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg13395646 chr4:1353034 KIAA1530 -0.41 -6.09 -0.31 3.1e-9 Longevity; LIHC cis rs1707322 0.686 rs3014242 chr1:46087577 G/A cg24296786 chr1:45957014 TESK2 0.42 6.1 0.31 2.93e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10489202 0.608 rs6657019 chr1:168079669 T/C cg24449463 chr1:168025552 DCAF6 -0.53 -8.07 -0.4 1.17e-14 Schizophrenia; LIHC cis rs1707322 1.000 rs3922886 chr1:46473902 A/T cg03146154 chr1:46216737 IPP 0.47 7.52 0.38 5e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs61990749 0.544 rs176979 chr14:78198072 A/C cg23188588 chr14:78226832 SNW1;C14orf178 0.63 10.45 0.49 2.23e-22 Fibroblast growth factor basic levels; LIHC cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg18357526 chr6:26021779 HIST1H4A 0.61 8.5 0.42 6.02e-16 Blood metabolite levels; LIHC cis rs611744 0.538 rs2298605 chr8:109272006 T/C cg21045802 chr8:109455806 TTC35 0.62 11.09 0.51 1.26e-24 Dupuytren's disease; LIHC cis rs2302190 0.882 rs8073754 chr17:56618030 C/T cg12560992 chr17:57184187 TRIM37 0.7 8.94 0.44 2.45e-17 Vitamin D levels; LIHC cis rs912057 0.965 rs1294415 chr6:6740633 G/A cg06612196 chr6:6737390 NA 0.51 9.35 0.45 1.14e-18 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg09222892 chr1:25734099 RHCE 0.48 8.89 0.43 3.55e-17 Erythrocyte sedimentation rate; LIHC cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg02951883 chr7:2050386 MAD1L1 -0.73 -12.05 -0.55 4.07e-28 Schizophrenia; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC trans rs17685 0.712 rs10275521 chr7:75770972 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10276381 0.786 rs740261 chr7:28241276 A/G cg23620719 chr7:28220237 JAZF1 0.62 7.25 0.36 2.84e-12 Crohn's disease; LIHC cis rs12478296 0.792 rs6738361 chr2:243014257 C/T cg05760424 chr2:242988095 NA -0.5 -6.77 -0.34 5.51e-11 Obesity-related traits; LIHC trans rs916888 0.821 rs199506 chr17:44859031 A/G cg22968622 chr17:43663579 NA -1.17 -13.04 -0.58 7.98e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7772486 0.754 rs4360151 chr6:146255079 A/C cg23711669 chr6:146136114 FBXO30 -0.62 -10.87 -0.51 7.67e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs26868 0.766 rs30995 chr16:2248017 C/T cg25665528 chr16:2260870 C16orf79 0.37 6.5 0.33 2.92e-10 Height; LIHC cis rs2274273 0.905 rs17128183 chr14:55579513 C/T cg04306507 chr14:55594613 LGALS3 -0.31 -6.06 -0.31 3.62e-9 Protein biomarker; LIHC cis rs6545883 0.929 rs2592352 chr2:61665336 C/T cg15711740 chr2:61764176 XPO1 -0.43 -6.06 -0.31 3.67e-9 Tuberculosis; LIHC cis rs9503598 0.610 rs1328687 chr6:3468377 A/C cg00476032 chr6:3446245 SLC22A23 0.4 7.67 0.38 1.77e-13 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs1144333 1.000 rs17097836 chr1:76462006 T/A cg10523679 chr1:76189770 ACADM 0.42 5.96 0.31 6.4e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs9393692 0.905 rs4412192 chr6:26290377 A/G cg05868516 chr6:26286170 HIST1H4H -0.39 -5.95 -0.31 6.57e-9 Educational attainment; LIHC cis rs11711311 1.000 rs7649590 chr3:113447267 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.42 7.88 0.39 4.34e-14 IgG glycosylation; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg06535952 chr19:56126775 NA 0.43 6.4 0.33 5.03e-10 Alopecia areata; LIHC cis rs11785400 0.793 rs4301430 chr8:143737416 A/G cg24634471 chr8:143751801 JRK 0.47 7.58 0.38 3.32e-13 Schizophrenia; LIHC cis rs2073300 1.000 rs6132628 chr20:23446734 G/A cg12062639 chr20:23401060 NAPB 0.85 9.96 0.47 1.06e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg11301795 chr4:187892539 NA -0.28 -7.17 -0.36 4.77e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs3812565 0.530 rs10781538 chr9:139320929 C/G cg14169450 chr9:139327907 INPP5E -0.38 -6.35 -0.32 6.72e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs919433 0.680 rs787983 chr2:198345797 C/T cg03934865 chr2:198174659 NA 0.51 7.99 0.4 2.06e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2952156 0.684 rs931992 chr17:37821435 G/T cg07936489 chr17:37558343 FBXL20 -0.45 -6.76 -0.34 6.04e-11 Asthma; LIHC cis rs7100689 0.577 rs756208 chr10:82041751 A/G cg01528321 chr10:82214614 TSPAN14 0.87 11.76 0.54 4.85e-27 Post bronchodilator FEV1; LIHC cis rs79149102 0.579 rs12593542 chr15:75282147 C/G cg16226627 chr15:75307476 SCAMP5 0.52 9.74 0.47 6.21e-20 Lung cancer; LIHC cis rs10911251 0.528 rs2147584 chr1:183074764 T/C ch.1.3577855R chr1:183094577 LAMC1 0.62 10.93 0.51 4.56e-24 Colorectal cancer; LIHC cis rs2842992 0.830 rs2758352 chr6:160122921 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.55 9.61 0.46 1.59e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg03806693 chr22:41940476 POLR3H 0.94 10.21 0.48 1.51e-21 Vitiligo; LIHC cis rs7071206 1.000 rs7071206 chr10:79401316 C/T cg07817648 chr10:79422355 NA 0.31 6.7 0.34 8.77e-11 Bone mineral density; LIHC cis rs600806 0.676 rs573491 chr1:110026891 T/G cg08911820 chr1:110026001 ATXN7L2 0.55 6.8 0.35 4.67e-11 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.645 rs10128731 chr11:50023554 G/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs7903847 0.602 rs7916665 chr10:99157573 T/G cg06359132 chr10:99160096 RRP12 -0.42 -6.51 -0.33 2.7e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9814567 1.000 rs9871305 chr3:134213538 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 -0.39 -5.78 -0.3 1.73e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2153535 0.580 rs9378552 chr6:8463748 G/A cg21535247 chr6:8435926 SLC35B3 0.62 8.15 0.4 6.8e-15 Motion sickness; LIHC cis rs9807989 0.507 rs6743516 chr2:103036335 A/G cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma; LIHC cis rs6840360 0.554 rs4643789 chr4:152726691 C/T cg22705602 chr4:152727874 NA -0.37 -8.09 -0.4 1.02e-14 Intelligence (multi-trait analysis); LIHC cis rs12464483 0.524 rs1348898 chr2:30888026 C/A cg17749961 chr2:30669863 LCLAT1 0.46 5.9 0.3 8.95e-9 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs12477438 0.748 rs4851185 chr2:99666497 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs7592578 0.639 rs61709084 chr2:191287685 A/C cg27211696 chr2:191398769 TMEM194B -0.49 -6.45 -0.33 3.85e-10 Diastolic blood pressure; LIHC cis rs763121 0.853 rs5757200 chr22:39043491 T/G cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs896854 0.738 rs481887 chr8:95967838 A/G cg16049864 chr8:95962084 TP53INP1 0.59 9.6 0.46 1.74e-19 Type 2 diabetes; LIHC cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg24549020 chr5:56110836 MAP3K1 0.49 6.27 0.32 1.06e-9 Initial pursuit acceleration; LIHC cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg11644478 chr21:40555479 PSMG1 0.82 10.34 0.49 5.56e-22 Cognitive function; LIHC cis rs7071206 0.947 rs11002226 chr10:79399656 T/A cg07817648 chr10:79422355 NA -0.35 -7.25 -0.36 2.88e-12 Bone mineral density; LIHC cis rs6752107 0.935 rs11690131 chr2:234148383 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.47 7.0 0.35 1.33e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2629540 0.766 rs10794177 chr10:126407409 G/C cg20435097 chr10:126320824 FAM53B -0.41 -5.98 -0.31 5.5e-9 Cocaine dependence; LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg02869306 chr7:64672164 INTS4L1 0.28 6.05 0.31 3.73e-9 Calcium levels; LIHC cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg06212747 chr3:49208901 KLHDC8B 0.64 8.74 0.43 1.04e-16 Menarche (age at onset); LIHC cis rs68170813 0.559 rs78553765 chr7:106930787 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs9309473 0.528 rs2091022 chr2:73564570 G/A cg20560298 chr2:73613845 ALMS1 -0.46 -7.13 -0.36 5.91e-12 Metabolite levels; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg11905131 chr22:24372483 LOC391322 0.65 8.54 0.42 4.46e-16 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC trans rs9914544 1.000 rs8066385 chr17:18761133 C/T cg04702396 chr17:15466718 FAM18B2 0.44 6.72 0.34 7.43e-11 Educational attainment (years of education); LIHC cis rs9473924 0.505 rs9463663 chr6:50902266 G/A cg14470998 chr6:50812995 TFAP2B 0.93 10.85 0.51 9.2e-24 Body mass index; LIHC cis rs4730250 0.655 rs4727671 chr7:106876045 A/G cg02696742 chr7:106810147 HBP1 -0.5 -5.86 -0.3 1.07e-8 Osteoarthritis; LIHC cis rs2997447 0.723 rs2802336 chr1:26473758 A/C cg19633962 chr1:26362018 EXTL1 -0.54 -6.31 -0.32 8.46e-10 QRS complex (12-leadsum); LIHC cis rs6500602 0.627 rs709632 chr16:4587811 C/G cg08645402 chr16:4508243 NA -0.34 -5.99 -0.31 5.25e-9 Schizophrenia; LIHC cis rs597539 0.652 rs613128 chr11:68638058 G/T cg06028808 chr11:68637592 NA 0.43 5.84 0.3 1.21e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2404602 0.669 rs12916324 chr15:77179603 G/A cg23625390 chr15:77176239 SCAPER 0.35 5.74 0.3 2.04e-8 Blood metabolite levels; LIHC cis rs2153535 0.580 rs1932282 chr6:8477330 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs2303745 0.589 rs1864115 chr19:17393327 G/C cg10664184 chr19:17420304 DDA1 0.45 5.74 0.3 2.12e-8 Systemic lupus erythematosus; LIHC cis rs876084 0.505 rs11985173 chr8:121107511 G/A cg06265175 chr8:121136014 COL14A1 0.48 7.72 0.39 1.34e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7487075 0.930 rs11183468 chr12:46806261 A/T cg22049899 chr12:47219821 SLC38A4 0.34 6.02 0.31 4.6e-9 Itch intensity from mosquito bite; LIHC cis rs2576037 0.526 rs649076 chr18:44414614 A/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 2.04e-10 Personality dimensions; LIHC cis rs2839186 0.903 rs61182475 chr21:47707050 T/A cg13126279 chr21:47581558 C21orf56 -0.38 -5.95 -0.31 6.52e-9 Testicular germ cell tumor; LIHC cis rs9583531 0.600 rs7986286 chr13:111357207 A/G cg24331049 chr13:111365604 ING1 0.77 13.03 0.58 8.91e-32 Coronary artery disease; LIHC cis rs67311347 1.000 rs2168111 chr3:40395325 T/G cg24209194 chr3:40518798 ZNF619 0.42 5.97 0.31 6.06e-9 Renal cell carcinoma; LIHC trans rs4843747 0.749 rs13333619 chr16:88072076 C/T cg09140114 chr16:29324813 RUNDC2C -0.44 -6.1 -0.31 2.82e-9 Menopause (age at onset); LIHC cis rs831571 0.703 rs55714137 chr3:64076779 A/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.58 -6.62 -0.34 1.35e-10 Type 2 diabetes; LIHC trans rs2727020 0.729 rs10839268 chr11:49380328 G/A cg18944383 chr4:111397179 ENPEP 0.26 6.3 0.32 9.32e-10 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20211779 chr11:34378921 ABTB2 0.45 6.05 0.31 3.78e-9 Lung function (FEV1/FVC); LIHC cis rs6061231 0.837 rs6121558 chr20:60961365 A/G cg03945807 chr20:60948434 NA 0.44 6.72 0.34 7.46e-11 Colorectal cancer; LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.78 -14.86 -0.63 6.95e-39 Prudent dietary pattern; LIHC cis rs13118159 0.651 rs4974599 chr4:1314430 A/C cg02475777 chr4:1388615 CRIPAK 0.39 5.83 0.3 1.31e-8 Longevity; LIHC cis rs2404602 0.692 rs58361452 chr15:76973372 T/C cg23625390 chr15:77176239 SCAPER 0.35 5.76 0.3 1.88e-8 Blood metabolite levels; LIHC cis rs4728302 0.869 rs12707129 chr7:133593177 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs9296092 0.517 rs7743445 chr6:33470600 G/T cg13560919 chr6:33536144 NA -0.38 -6.06 -0.31 3.58e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs1997103 1.000 rs4948012 chr7:55412578 A/C cg17469321 chr7:55412551 NA 0.49 7.19 0.36 3.98e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs11958404 0.719 rs72818153 chr5:157487035 T/C cg05962755 chr5:157440814 NA 1.01 11.68 0.53 9.69e-27 IgG glycosylation; LIHC cis rs1904096 0.506 rs6823404 chr4:95197520 C/T cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.29 -0.45 1.9e-18 Type 2 diabetes; LIHC trans rs35110281 0.776 rs62226866 chr21:45024186 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.22e-9 Mean corpuscular volume; LIHC cis rs796364 0.806 rs76112266 chr2:201087157 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.81 -8.96 -0.44 2.15e-17 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11587315 chr1:223254976 NA -0.47 -6.32 -0.32 8.33e-10 Systolic blood pressure; LIHC cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg07424592 chr7:64974309 NA -0.8 -9.29 -0.45 1.82e-18 Diabetic kidney disease; LIHC cis rs5753618 0.561 rs2283881 chr22:31638932 G/A cg07713946 chr22:31675144 LIMK2 -0.43 -7.81 -0.39 7.12e-14 Colorectal cancer; LIHC cis rs56104184 0.830 rs17272645 chr19:49342366 C/G cg15549821 chr19:49342101 PLEKHA4 1.18 11.4 0.52 1.02e-25 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs1005277 0.579 rs2474599 chr10:38438939 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2302190 0.882 rs1974586 chr17:56640731 C/T cg12560992 chr17:57184187 TRIM37 0.68 8.8 0.43 7e-17 Vitamin D levels; LIHC cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.84 0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg11494091 chr17:61959527 GH2 -0.46 -8.2 -0.41 4.95e-15 Prudent dietary pattern; LIHC trans rs7618501 0.933 rs3811695 chr3:49761613 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg17971929 chr21:40555470 PSMG1 0.86 10.36 0.49 4.56e-22 Cognitive function; LIHC cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg11766577 chr21:47581405 C21orf56 -0.42 -6.83 -0.35 3.88e-11 Testicular germ cell tumor; LIHC cis rs58688157 0.960 rs1055382 chr11:612182 T/C cg16486109 chr11:613632 IRF7 0.61 6.81 0.35 4.44e-11 Systemic lupus erythematosus; LIHC cis rs9733 0.596 rs6686525 chr1:150635811 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.22 0.32 1.43e-9 Tonsillectomy; LIHC cis rs9814567 1.000 rs13096604 chr3:134250099 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg05590025 chr7:65112418 INTS4L2 -0.67 -7.36 -0.37 1.34e-12 Diabetic kidney disease; LIHC cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.88 0.3 9.86e-9 Menopause (age at onset); LIHC cis rs10791097 0.765 rs10894269 chr11:130722789 C/T cg14779329 chr11:130786720 SNX19 0.38 5.86 0.3 1.11e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.12 -0.44 6.36e-18 Bipolar disorder; LIHC cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.44 0.37 8.24e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.44 5.83 0.3 1.27e-8 Bipolar disorder; LIHC cis rs7843479 0.601 rs4872207 chr8:21842751 C/G cg17168535 chr8:21777572 XPO7 -0.61 -10.59 -0.5 7.65e-23 Mean corpuscular volume; LIHC cis rs7560272 0.695 rs13022149 chr2:73641515 T/A cg20560298 chr2:73613845 ALMS1 0.36 5.73 0.3 2.16e-8 Schizophrenia; LIHC cis rs748404 0.676 rs4401024 chr15:43650335 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.86 0.43 4.31e-17 Lung cancer; LIHC cis rs7223966 1.000 rs8081612 chr17:61724695 A/G cg05941027 chr17:61774174 LIMD2 -0.31 -6.26 -0.32 1.14e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.97 -12.37 -0.56 2.76e-29 Alzheimer's disease; LIHC cis rs2070488 0.662 rs6599203 chr3:38487802 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.57 8.07 0.4 1.19e-14 Electrocardiographic conduction measures; LIHC cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg00106254 chr7:1943704 MAD1L1 -0.4 -6.52 -0.33 2.5e-10 Bipolar disorder and schizophrenia; LIHC cis rs10847980 0.590 rs75217947 chr12:123346177 G/C cg22842854 chr12:123319900 HIP1R 0.93 10.51 0.49 1.41e-22 Adiponectin levels; LIHC cis rs9324022 0.858 rs1004572 chr14:101178330 G/A cg18089426 chr14:101175970 NA 0.48 6.41 0.33 4.91e-10 Plateletcrit; LIHC cis rs7095944 0.614 rs7099316 chr10:126469005 G/A cg08799069 chr10:126477246 METTL10 -0.39 -7.0 -0.35 1.35e-11 Asthma; LIHC cis rs34172651 0.837 rs1978451 chr16:24818286 C/G cg04756594 chr16:24857601 SLC5A11 0.44 6.89 0.35 2.64e-11 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg21782813 chr7:2030301 MAD1L1 0.44 7.38 0.37 1.22e-12 Bipolar disorder and schizophrenia; LIHC cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs1003719 0.679 rs1133001 chr21:38512956 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.15 -0.52 7.67e-25 Eye color traits; LIHC cis rs7267979 0.966 rs6037083 chr20:25290543 T/C cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.72 -0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2404602 1.000 rs2404602 chr15:77030792 A/G cg23625390 chr15:77176239 SCAPER 0.39 6.63 0.34 1.29e-10 Blood metabolite levels; LIHC cis rs4843747 0.671 rs9921236 chr16:88117015 G/T cg06050784 chr16:88016603 BANP 0.4 7.28 0.37 2.36e-12 Menopause (age at onset); LIHC cis rs9303280 0.901 rs7219923 chr17:38074518 C/T cg11212589 chr17:38028394 ZPBP2 -0.33 -6.66 -0.34 1.11e-10 Self-reported allergy; LIHC cis rs1395 0.744 rs62130714 chr2:27532870 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.46 -6.08 -0.31 3.21e-9 Blood metabolite levels; LIHC trans rs7618501 0.633 rs12496973 chr3:50002245 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.56 9.23 0.45 2.83e-18 Intelligence (multi-trait analysis); LIHC cis rs748404 0.690 rs2467737 chr15:43737188 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.92 0.39 3.47e-14 Lung cancer; LIHC cis rs523522 0.962 rs4766968 chr12:120947788 G/C cg27279351 chr12:120934652 DYNLL1 0.66 11.74 0.54 5.54e-27 High light scatter reticulocyte count; LIHC cis rs10791097 0.694 rs1893017 chr11:130756253 C/T cg12179176 chr11:130786555 SNX19 0.85 13.94 0.6 2.63e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12458462 0.892 rs2242175 chr18:77464406 G/A cg11879182 chr18:77439856 CTDP1 0.82 13.71 0.6 2.07e-34 Monocyte count; LIHC cis rs826838 0.935 rs10875816 chr12:38955014 C/A cg26384229 chr12:38710491 ALG10B 0.95 13.02 0.58 9.71e-32 Heart rate; LIHC cis rs1707322 0.721 rs6429575 chr1:46134216 G/C cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12493885 0.818 rs60023390 chr3:153771056 C/T cg10247383 chr3:153839028 SGEF 0.65 6.13 0.31 2.41e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7534824 0.625 rs72736234 chr1:101526098 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.7 7.12 0.36 6.25e-12 Refractive astigmatism; LIHC cis rs9527 0.571 rs12219246 chr10:104613355 A/G cg15744005 chr10:104629667 AS3MT -0.46 -10.54 -0.5 1.15e-22 Arsenic metabolism; LIHC cis rs2952156 0.920 rs9675194 chr17:37833805 A/G cg00129232 chr17:37814104 STARD3 -0.55 -10.44 -0.49 2.57e-22 Asthma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22672078 chr12:132628386 DDX51;NOC4L -0.42 -6.19 -0.32 1.68e-9 Pancreatic cancer; LIHC trans rs13381277 1.000 rs9959129 chr18:74329661 A/G cg17352830 chr21:37617589 DOPEY2 0.54 6.47 0.33 3.46e-10 Dental caries; LIHC cis rs2439831 0.702 rs3759791 chr15:44090798 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.51 6.42 0.33 4.51e-10 Lung cancer in ever smokers; LIHC cis rs7296418 0.961 rs10848428 chr12:123572495 C/T cg05973401 chr12:123451056 ABCB9 0.5 7.73 0.39 1.24e-13 Platelet count; LIHC trans rs11098499 0.954 rs6834796 chr4:120414693 A/C cg25214090 chr10:38739885 LOC399744 0.58 9.43 0.45 6.45e-19 Corneal astigmatism; LIHC cis rs546131 0.928 rs552627 chr11:34826680 G/A cg11058730 chr11:34937778 PDHX;APIP 0.58 8.88 0.43 3.78e-17 Lung disease severity in cystic fibrosis; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.45e-13 Prudent dietary pattern; LIHC cis rs10744422 0.925 rs3825143 chr12:123352179 C/T cg18912006 chr12:123335444 HIP1R -0.61 -7.29 -0.37 2.1e-12 Schizophrenia; LIHC cis rs10870270 0.912 rs7079991 chr10:133736130 A/G cg26149184 chr10:133730230 NA 0.46 7.34 0.37 1.56e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs507080 0.922 rs4938524 chr11:118552074 G/T cg04173919 chr11:118528438 PHLDB1 0.33 6.17 0.32 1.92e-9 Serum metabolite levels; LIHC cis rs7072216 0.763 rs4475861 chr10:100164989 C/T cg26618903 chr10:100175079 PYROXD2 -0.38 -6.22 -0.32 1.44e-9 Metabolite levels; LIHC trans rs10506458 1.000 rs1495013 chr12:63428188 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.77 -10.9 -0.51 6.08e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg00149659 chr3:10157352 C3orf10 0.68 7.12 0.36 6.57e-12 Alzheimer's disease; LIHC cis rs921968 0.643 rs559722 chr2:219398159 A/G cg02985541 chr2:219472218 PLCD4 0.45 8.68 0.42 1.62e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs2073300 0.609 rs6137936 chr20:23385232 C/T cg16736954 chr20:23401023 NAPB 0.71 8.28 0.41 2.86e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1401999 0.690 rs3805112 chr3:183645662 C/T cg05044414 chr3:183734942 ABCC5 0.31 5.81 0.3 1.42e-8 Anterior chamber depth; LIHC cis rs875971 0.862 rs709596 chr7:65825913 A/G cg18876405 chr7:65276391 NA 0.35 6.43 0.33 4.22e-10 Aortic root size; LIHC cis rs2637266 0.935 rs7921790 chr10:78368253 T/C cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC cis rs11628318 0.614 rs7149667 chr14:103129441 G/A cg23461800 chr14:103021989 NA 0.45 6.3 0.32 8.99e-10 Platelet count; LIHC cis rs9534288 0.797 rs7995256 chr13:46579414 A/T cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs7959452 0.535 rs7135092 chr12:69658330 T/C cg14784868 chr12:69753453 YEATS4 0.85 15.96 0.65 3.1e-43 Blood protein levels; LIHC cis rs9914988 0.887 rs8078402 chr17:27145124 T/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs4925386 0.959 rs4925385 chr20:60920624 A/G cg24112000 chr20:60950667 NA 0.45 7.14 0.36 5.48e-12 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs801193 0.548 rs2109297 chr7:66122384 G/A cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs651907 0.557 rs11917682 chr3:101355427 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 11.87 0.54 1.95e-27 Colorectal cancer; LIHC cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg06634786 chr22:41940651 POLR3H 0.8 8.77 0.43 8.83e-17 Vitiligo; LIHC cis rs2050392 0.590 rs303433 chr10:30714963 A/T cg25182066 chr10:30743637 MAP3K8 -0.6 -9.61 -0.46 1.59e-19 Inflammatory bowel disease; LIHC cis rs933688 1.000 rs10474353 chr5:90732285 A/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 21.03 0.75 1.37e-63 Smoking behavior; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg10150615 chr22:24372951 LOC391322 0.55 7.22 0.36 3.3e-12 Urinary 1,3-butadiene metabolite levels in smokers; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03532005 chr7:56119028 CCT6A;PSPH -0.41 -6.32 -0.32 8.29e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs4808199 0.948 rs7250368 chr19:19452763 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.57 8.24 0.41 3.74e-15 Nonalcoholic fatty liver disease; LIHC cis rs3862260 1.000 rs3862260 chr1:120160789 G/A cg11530693 chr1:120165357 ZNF697 0.47 7.53 0.38 4.59e-13 Systemic lupus erythematosus; LIHC cis rs2836974 0.644 rs4818017 chr21:40690561 G/T cg11890956 chr21:40555474 PSMG1 -0.48 -7.84 -0.39 5.71e-14 Cognitive function; LIHC cis rs9457247 0.967 rs2149092 chr6:167372978 C/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.94 -0.47 1.26e-20 Crohn's disease; LIHC cis rs61712019 0.643 rs12997025 chr2:77711560 G/T cg11252801 chr2:77748917 LRRTM4 0.55 7.59 0.38 3.17e-13 Schizophrenia; LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.71 11.46 0.53 6.18e-26 Height; LIHC cis rs4561483 0.801 rs154148 chr16:11956478 T/C cg08843971 chr16:11963173 GSPT1 -0.42 -8.29 -0.41 2.67e-15 Testicular germ cell tumor; LIHC cis rs72781680 0.898 rs72788302 chr2:24107246 C/T cg08917208 chr2:24149416 ATAD2B 0.98 8.61 0.42 2.7e-16 Lymphocyte counts; LIHC cis rs208520 0.690 rs12194057 chr6:66745616 A/G cg07460842 chr6:66804631 NA 0.78 9.07 0.44 9.76e-18 Exhaled nitric oxide output; LIHC cis rs8081395 0.834 rs11650106 chr17:57850251 C/T cg02344993 chr17:57696989 CLTC -0.43 -6.96 -0.35 1.72e-11 White blood cell count; LIHC cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg06238570 chr21:40685208 BRWD1 -0.52 -8.73 -0.43 1.18e-16 Cognitive function; LIHC cis rs2857078 0.720 rs9906669 chr17:42305706 A/G cg13607699 chr17:42295918 UBTF 0.65 11.63 0.53 1.39e-26 Red cell distribution width;Reticulocyte count; LIHC cis rs9858542 1.000 rs11130213 chr3:49712297 C/T cg03060546 chr3:49711283 APEH -0.62 -8.41 -0.41 1.1e-15 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1443512 0.704 rs4759308 chr12:54329031 A/T cg25024717 chr12:54324583 NA -0.32 -6.33 -0.32 7.9e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs4423214 0.610 rs12789253 chr11:71125765 G/A cg05163923 chr11:71159392 DHCR7 0.76 11.64 0.53 1.36e-26 Vitamin D levels; LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg19635926 chr16:89946313 TCF25 0.51 7.16 0.36 4.96e-12 Skin colour saturation; LIHC cis rs400736 0.930 rs2745722 chr1:8056669 G/A cg25007680 chr1:8021821 PARK7 0.61 9.92 0.47 1.46e-20 Response to antidepressants and depression; LIHC cis rs3733606 0.503 rs11734132 chr4:6891519 C/G cg05012661 chr4:6891264 NA -0.41 -6.75 -0.34 6.53e-11 Platelet count; LIHC cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg26818010 chr10:134567672 INPP5A -0.72 -9.19 -0.44 3.97e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17685 0.753 rs1639617 chr7:75701728 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1029738 0.659 rs1608553 chr7:22896231 G/C cg22407942 chr7:22894828 SNORD93 -0.34 -6.46 -0.33 3.68e-10 Fibrinogen levels; LIHC cis rs9790314 0.586 rs16832279 chr3:161120483 C/T cg03342759 chr3:160939853 NMD3 -0.54 -8.53 -0.42 4.75e-16 Morning vs. evening chronotype; LIHC cis rs4819852 0.958 rs9606203 chr22:19972118 C/A cg07821417 chr22:19972146 ARVCF 0.47 6.67 0.34 1.06e-10 Pulse pressure; LIHC cis rs3736485 0.966 rs10467924 chr15:51787579 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.21 -0.32 1.5e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs801193 1.000 rs10234018 chr7:66146284 A/T cg26939375 chr7:64535504 NA -0.43 -6.89 -0.35 2.67e-11 Aortic root size; LIHC cis rs6867032 1.000 rs7729761 chr5:2015783 G/T cg26168224 chr5:2018326 NA 0.31 7.57 0.38 3.48e-13 Gut microbiome composition (winter); LIHC cis rs10791097 0.694 rs10894273 chr11:130742155 G/T cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25958857 chr12:53448399 TENC1 -0.44 -6.34 -0.32 7.07e-10 Cognitive function; LIHC cis rs10876993 0.893 rs1678504 chr12:58085498 G/C cg18357645 chr12:58087776 OS9 0.55 8.88 0.43 3.76e-17 Celiac disease or Rheumatoid arthritis; LIHC cis rs6762 0.748 rs28735718 chr11:839629 A/G cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.61 -0.46 1.6e-19 Mean platelet volume; LIHC cis rs2580764 0.678 rs2588521 chr2:55203931 C/G cg09592903 chr2:55203963 RTN4 0.76 14.21 0.61 2.5e-36 Mean platelet volume; LIHC cis rs1256061 0.564 rs1256043 chr14:64734282 A/G cg23250157 chr14:64679961 SYNE2 0.4 6.03 0.31 4.25e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs12144094 0.882 rs10218713 chr1:120247899 A/G cg20995928 chr1:120229863 NA 0.42 7.29 0.37 2.2e-12 Height; LIHC cis rs60871478 1.000 rs62432860 chr7:807522 G/C cg13844804 chr7:814759 HEATR2 0.44 5.89 0.3 9.46e-9 Cerebrospinal P-tau181p levels; LIHC cis rs12701220 0.500 rs6463224 chr7:1140418 C/A cg23978390 chr7:1156363 C7orf50 0.64 8.01 0.4 1.81e-14 Bronchopulmonary dysplasia; LIHC cis rs7818688 0.745 rs16917117 chr8:95909498 C/T cg16049864 chr8:95962084 TP53INP1 -0.51 -5.98 -0.31 5.72e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg05552183 chr6:42928497 GNMT 0.82 12.15 0.55 1.81e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6430585 0.528 rs309165 chr2:136667301 T/C cg15123519 chr2:136567270 LCT -0.32 -5.72 -0.3 2.29e-8 Corneal structure; LIHC cis rs3806843 0.966 rs2563266 chr5:140136915 C/A cg26395211 chr5:140044315 WDR55 0.41 6.15 0.32 2.17e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs208520 0.690 rs2144081 chr6:66824972 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -8.11 -0.4 9.12e-15 Exhaled nitric oxide output; LIHC cis rs12458462 0.851 rs62097746 chr18:77487508 G/A cg11879182 chr18:77439856 CTDP1 0.83 13.38 0.59 4.01e-33 Monocyte count; LIHC cis rs896854 0.517 rs2013597 chr8:95951807 G/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.45 -0.37 7.77e-13 Type 2 diabetes; LIHC cis rs6754311 0.773 rs1435576 chr2:136641882 A/T cg25344623 chr2:136566232 LCT -0.39 -7.89 -0.39 4.09e-14 Mosquito bite size; LIHC cis rs36051895 0.589 rs7850294 chr9:5191128 C/T cg02405213 chr9:5042618 JAK2 0.69 11.68 0.53 9.14e-27 Pediatric autoimmune diseases; LIHC cis rs2455799 0.573 rs2455831 chr3:15751583 T/A cg12698662 chr3:15914712 MIR563 -0.39 -7.17 -0.36 4.54e-12 Mean platelet volume; LIHC cis rs2439831 1.000 rs2467736 chr15:43784917 T/C cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.34e-9 Lung cancer in ever smokers; LIHC cis rs8072100 0.840 rs56952963 chr17:45493826 T/C cg25173405 chr17:45401733 C17orf57 -0.41 -5.72 -0.3 2.37e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7224737 1.000 rs2285657 chr17:40272594 C/A cg20291162 chr17:40259547 DHX58 -0.38 -5.75 -0.3 1.97e-8 Fibrinogen levels; LIHC cis rs1873147 0.569 rs59418037 chr15:63310871 A/G cg12160578 chr15:63334699 TPM1 0.67 8.87 0.43 4.13e-17 Orofacial clefts; LIHC cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg18357526 chr6:26021779 HIST1H4A 0.88 12.06 0.55 3.77e-28 Intelligence (multi-trait analysis); LIHC cis rs798554 0.757 rs1713919 chr7:2864706 C/A cg19346786 chr7:2764209 NA -0.46 -6.68 -0.34 9.68e-11 Height; LIHC cis rs4718428 0.705 rs12536410 chr7:66254290 G/A cg18252515 chr7:66147081 NA -0.7 -9.52 -0.46 3.31e-19 Corneal structure; LIHC cis rs9902453 1.000 rs4328498 chr17:28344276 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg02707576 chr5:139682775 PFDN1 0.38 6.09 0.31 2.98e-9 Calcium levels; LIHC cis rs12478296 1.000 rs12478296 chr2:243048760 A/G cg18898632 chr2:242989856 NA 0.52 7.02 0.35 1.22e-11 Obesity-related traits; LIHC cis rs9303401 0.614 rs2240719 chr17:56582477 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.92 12.49 0.56 9.2e-30 Cognitive test performance; LIHC cis rs6598955 0.543 rs6690461 chr1:26543097 T/A cg04990556 chr1:26633338 UBXN11 0.77 11.13 0.52 8.89e-25 Obesity-related traits; LIHC cis rs68170813 0.559 rs1002935 chr7:106832361 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs1728785 0.901 rs11075687 chr16:68655894 T/C cg02972257 chr16:68554789 NA -0.53 -6.1 -0.31 2.83e-9 Ulcerative colitis; LIHC cis rs7572733 0.555 rs1435569 chr2:198718667 G/C cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs6582630 0.555 rs10880544 chr12:38473464 G/C cg26384229 chr12:38710491 ALG10B 0.66 9.13 0.44 6.3e-18 Drug-induced liver injury (flucloxacillin); LIHC cis rs10876993 0.890 rs2640630 chr12:58067267 T/C cg15848620 chr12:58087721 OS9 -0.58 -7.88 -0.39 4.52e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs11792861 0.926 rs1333344 chr9:111776224 C/T cg13535736 chr9:111863775 C9orf5 -0.4 -6.13 -0.31 2.37e-9 Menarche (age at onset); LIHC cis rs9640161 0.742 rs2108854 chr7:150017408 C/T cg10018233 chr7:150070692 REPIN1 -0.54 -9.21 -0.45 3.28e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs2439831 0.850 rs10163054 chr15:44047638 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.42 0.41 1.09e-15 Lung cancer in ever smokers; LIHC cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2455601 0.786 rs10279 chr11:8969309 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.41 -5.79 -0.3 1.6e-8 Schizophrenia; LIHC cis rs875971 0.577 rs34888281 chr7:65585771 C/T cg18876405 chr7:65276391 NA -0.52 -8.37 -0.41 1.51e-15 Aortic root size; LIHC cis rs7772486 0.875 rs12194437 chr6:146411440 A/G cg23711669 chr6:146136114 FBXO30 0.64 10.83 0.51 1.07e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7927771 0.507 rs12366244 chr11:47882130 C/A cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.34e-24 Subjective well-being; LIHC cis rs17384381 1.000 rs17384381 chr1:85897570 C/G cg16011679 chr1:85725395 C1orf52 0.8 9.11 0.44 7.17e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 1.000 rs1076394 chr3:47322781 G/A cg16586182 chr3:47516702 SCAP 0.58 10.74 0.5 2.14e-23 Colorectal cancer; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg17842912 chr5:139060919 CXXC5 0.5 6.37 0.33 6.22e-10 Lung function (FEV1); LIHC cis rs6500602 0.647 rs3747600 chr16:4586222 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.46 6.67 0.34 1.01e-10 Schizophrenia; LIHC cis rs7089973 0.624 rs10885613 chr10:116589400 G/A cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs3768617 1.000 rs2027077 chr1:183073453 G/C ch.1.3577855R chr1:183094577 LAMC1 0.49 7.89 0.39 4.22e-14 Fuchs's corneal dystrophy; LIHC cis rs2839627 0.598 rs9975526 chr21:44266573 T/A cg18192155 chr21:44258298 NA 0.4 6.27 0.32 1.09e-9 Information processing speed; LIHC cis rs7662987 0.517 rs2602883 chr4:100040914 A/T cg12011299 chr4:100065546 ADH4 0.63 10.34 0.49 5.59e-22 Smoking initiation; LIHC cis rs3008870 0.755 rs3929738 chr1:67397865 T/C cg02640540 chr1:67518911 SLC35D1 0.41 6.38 0.33 5.76e-10 Lymphocyte percentage of white cells; LIHC cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg07061783 chr6:25882402 NA -0.79 -10.94 -0.51 4.42e-24 Uric acid levels; LIHC cis rs2033711 0.905 rs1077420 chr19:58968875 A/C cg13877915 chr19:58951672 ZNF132 0.59 9.06 0.44 9.94e-18 Uric acid clearance; LIHC cis rs1799949 0.773 rs2137990 chr17:41317896 T/A cg05368731 chr17:41323189 NBR1 -0.68 -11.3 -0.52 2.24e-25 Menopause (age at onset); LIHC cis rs9902453 0.934 rs4343336 chr17:28488236 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.32 0.45 1.47e-18 Coffee consumption (cups per day); LIHC cis rs9309711 0.621 rs12993215 chr2:3473727 T/C cg15541040 chr2:3486749 NA -0.45 -6.89 -0.35 2.71e-11 Neurofibrillary tangles; LIHC cis rs11864453 0.786 rs1050362 chr16:72130815 C/A cg16558253 chr16:72132732 DHX38 -0.52 -8.15 -0.4 7.01e-15 Fibrinogen levels; LIHC cis rs7726839 0.540 rs4957081 chr5:646418 G/C cg09021430 chr5:549028 NA -0.41 -8.36 -0.41 1.56e-15 Obesity-related traits; LIHC cis rs7520050 0.966 rs12409773 chr1:46358831 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.02 0.31 4.49e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1728785 1.000 rs7118 chr16:68600855 G/T cg02972257 chr16:68554789 NA -0.53 -6.13 -0.31 2.39e-9 Ulcerative colitis; LIHC cis rs965469 1.000 rs2236087 chr20:3255905 C/T cg25506879 chr20:3388711 C20orf194 -0.54 -6.14 -0.32 2.23e-9 IFN-related cytopenia; LIHC cis rs6429082 0.523 rs704718 chr1:235666159 A/T cg26050004 chr1:235667680 B3GALNT2 0.83 14.94 0.63 3.5e-39 Adiposity; LIHC cis rs7903847 0.667 rs3818787 chr10:99145179 T/C cg20016023 chr10:99160130 RRP12 -0.41 -6.59 -0.34 1.71e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6088580 0.634 rs4911151 chr20:32932273 T/C cg08999081 chr20:33150536 PIGU -0.66 -13.1 -0.58 4.72e-32 Glomerular filtration rate (creatinine); LIHC cis rs8114671 0.562 rs8116657 chr20:33476474 C/G cg07148914 chr20:33460835 GGT7 0.66 10.14 0.48 2.7e-21 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21775445 chr20:1373916 FKBP1A 0.46 6.57 0.33 1.83e-10 Pancreatic cancer; LIHC cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -5.73 -0.3 2.17e-8 Diastolic blood pressure; LIHC cis rs2836974 0.568 rs11910906 chr21:40685662 T/C cg11890956 chr21:40555474 PSMG1 -0.48 -7.68 -0.38 1.72e-13 Cognitive function; LIHC cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg10210624 chr19:58662595 ZNF329 0.74 7.48 0.38 6.2800000000000005e-13 Cholesterol, total; LIHC cis rs7927771 0.524 rs7929725 chr11:47881740 A/G cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.29e-24 Subjective well-being; LIHC cis rs853679 0.517 rs9380050 chr6:28048538 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs5753618 0.509 rs5997913 chr22:31593959 C/A cg07713946 chr22:31675144 LIMK2 -0.42 -7.38 -0.37 1.18e-12 Colorectal cancer; LIHC cis rs7520050 0.966 rs1707321 chr1:46505309 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.95 0.31 6.78e-9 Red blood cell count;Reticulocyte count; LIHC cis rs589448 0.902 rs528974 chr12:69765918 A/T cg20891283 chr12:69753455 YEATS4 0.95 22.46 0.77 2.7e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs67311347 1.000 rs977652 chr3:40479169 A/G cg09455208 chr3:40491958 NA 0.33 6.78 0.34 5.41e-11 Renal cell carcinoma; LIHC cis rs7945705 0.935 rs11042103 chr11:8888700 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.41 7.06 0.36 9.1e-12 Hemoglobin concentration; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg12154153 chr1:168195108 SFT2D2 0.61 6.07 0.31 3.41e-9 Mean platelet volume; LIHC cis rs6121246 0.697 rs6088857 chr20:30226764 G/C cg13852791 chr20:30311386 BCL2L1 0.8 8.05 0.4 1.4e-14 Mean corpuscular hemoglobin; LIHC cis rs965469 1.000 rs8123289 chr20:3253831 T/C cg25506879 chr20:3388711 C20orf194 -0.56 -6.36 -0.33 6.36e-10 IFN-related cytopenia; LIHC cis rs1816752 0.905 rs13428 chr13:25009441 C/G cg22771759 chr13:24902376 NA 0.32 6.7 0.34 8.43e-11 Obesity-related traits; LIHC cis rs9733 0.650 rs11204684 chr1:150608894 A/G cg17724175 chr1:150552817 MCL1 -0.39 -7.88 -0.39 4.26e-14 Tonsillectomy; LIHC cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg04944784 chr2:26401820 FAM59B -0.74 -9.3 -0.45 1.72e-18 Gut microbiome composition (summer); LIHC trans rs2727020 0.894 rs1880438 chr11:49370698 A/G cg18944383 chr4:111397179 ENPEP 0.28 6.52 0.33 2.56e-10 Coronary artery disease; LIHC cis rs11122272 0.705 rs2486731 chr1:231532511 C/T cg06096015 chr1:231504339 EGLN1 -0.43 -8.47 -0.42 7.37e-16 Hemoglobin concentration; LIHC cis rs7520050 0.966 rs4660898 chr1:46402171 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.0 0.31 5.05e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1005277 0.540 rs116205409 chr10:38478970 G/A cg25427524 chr10:38739819 LOC399744 -0.72 -14.26 -0.61 1.58e-36 Extrinsic epigenetic age acceleration; LIHC trans rs208520 0.837 rs208467 chr6:66914837 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.7 -7.79 -0.39 8.37e-14 Exhaled nitric oxide output; LIHC cis rs8078723 0.738 rs3816472 chr17:38142677 A/C cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.12 0.52 9.88e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs875971 0.862 rs2909688 chr7:65841612 C/A cg18252515 chr7:66147081 NA -0.46 -6.8 -0.35 4.55e-11 Aortic root size; LIHC cis rs1552244 0.608 rs3732962 chr3:10048951 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC trans rs1814175 0.645 rs28839231 chr11:50044292 G/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26336594 chr4:152330339 FAM160A1 -0.43 -6.25 -0.32 1.24e-9 Cognitive function; LIHC cis rs12188164 0.561 rs2251843 chr5:457955 C/T cg16584290 chr5:462447 EXOC3 -0.36 -5.85 -0.3 1.13e-8 Cystic fibrosis severity; LIHC cis rs6466055 0.777 rs10238507 chr7:104807207 G/T cg04380332 chr7:105027541 SRPK2 0.35 6.6 0.34 1.58e-10 Schizophrenia; LIHC cis rs2839186 0.934 rs2839194 chr21:47699437 T/G cg00612595 chr21:47717864 NA -0.36 -5.86 -0.3 1.1e-8 Testicular germ cell tumor; LIHC trans rs1941687 0.505 rs8091920 chr18:31303557 C/G cg27147174 chr7:100797783 AP1S1 -0.47 -7.16 -0.36 5.09e-12 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs11122272 0.735 rs2808591 chr1:231523421 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg22694153 chr1:46768912 LRRC41;UQCRH 0.43 6.87 0.35 3.05e-11 Calcium levels; LIHC cis rs3960554 0.569 rs10954750 chr7:75664921 C/G cg01364799 chr7:75623366 TMEM120A 0.54 7.71 0.38 1.42e-13 Eotaxin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13095604 chr12:12966124 DDX47 0.45 6.23 0.32 1.34e-9 Pancreatic cancer; LIHC cis rs7635838 0.892 rs9310379 chr3:11434143 C/T cg00170343 chr3:11313890 ATG7 -0.45 -7.17 -0.36 4.71e-12 HDL cholesterol; LIHC cis rs7071206 0.853 rs114936111 chr10:79430143 G/A cg07817648 chr10:79422355 NA -0.31 -6.68 -0.34 9.56e-11 Bone mineral density; LIHC cis rs727505 1.000 rs12111865 chr7:124498035 G/A cg23710748 chr7:124431027 NA -0.32 -5.91 -0.3 8.38e-9 Lewy body disease; LIHC cis rs4478037 0.818 rs17522946 chr3:33138777 A/G cg27203090 chr3:33138513 GLB1;TMPPE -0.48 -6.04 -0.31 3.95e-9 Major depressive disorder; LIHC cis rs7249142 0.549 rs12609573 chr19:19297567 C/T cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B 0.41 6.78 0.34 5.32e-11 IgG glycosylation; LIHC cis rs4654899 0.965 rs61779124 chr1:21513306 C/T cg08539965 chr1:21396338 EIF4G3 0.34 6.07 0.31 3.31e-9 Superior frontal gyrus grey matter volume; LIHC cis rs3018712 0.532 rs948863 chr11:68420974 G/A cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.17e-8 Total body bone mineral density; LIHC cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg10360323 chr17:41437877 NA 0.4 5.99 0.31 5.25e-9 Menopause (age at onset); LIHC cis rs35160687 0.644 rs1863061 chr2:86512907 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.36 5.83 0.3 1.26e-8 Night sleep phenotypes; LIHC trans rs11098499 0.909 rs7681214 chr4:120385320 C/A cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs7520050 0.808 rs11211196 chr1:46282296 A/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.93 0.31 7.33e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6963495 0.872 rs1569134 chr7:105158228 T/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg11062466 chr8:58055876 NA 0.49 7.01 0.35 1.27e-11 Developmental language disorder (linguistic errors); LIHC cis rs67311347 0.506 rs55962832 chr3:40244451 T/C cg10755058 chr3:40428713 ENTPD3 0.36 5.74 0.3 2.06e-8 Renal cell carcinoma; LIHC cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 8.9 0.43 3.29e-17 Menarche (age at onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg08434171 chr17:16284988 UBB -0.36 -6.42 -0.33 4.45e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg12310025 chr6:25882481 NA -1.1 -17.57 -0.69 1.08e-49 Urate levels; LIHC cis rs7833986 0.534 rs17759244 chr8:57033768 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.63 0.42 2.28e-16 Height; LIHC cis rs999943 0.810 rs57088429 chr6:33644189 G/A cg14003231 chr6:33640908 ITPR3 0.33 6.31 0.32 8.51e-10 Obesity (extreme); LIHC cis rs3741151 0.892 rs76854106 chr11:73027110 G/A cg17517138 chr11:73019481 ARHGEF17 0.93 6.93 0.35 2.04e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg04025307 chr7:1156635 C7orf50 0.6 10.43 0.49 2.61e-22 Longevity;Endometriosis; LIHC cis rs55665837 0.665 rs11023273 chr11:14630819 G/A cg25251204 chr11:14927456 NA 0.43 6.01 0.31 4.84e-9 Vitamin D levels; LIHC cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs2153535 0.580 rs9505455 chr6:8478622 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs7395581 0.959 rs59663860 chr11:47276350 G/C cg25783544 chr11:47291846 MADD 0.45 6.66 0.34 1.06e-10 HDL cholesterol; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.89 0.57 2.82e-31 Prudent dietary pattern; LIHC trans rs11014306 1.000 rs16925145 chr10:25198782 G/A cg17214381 chr4:188916668 ZFP42 -0.55 -6.24 -0.32 1.29e-9 Metabolite levels (Pyroglutamine); LIHC cis rs2281845 0.965 rs7516023 chr1:201085521 C/T cg01987224 chr1:201084466 NA -0.33 -6.03 -0.31 4.3e-9 Permanent tooth development; LIHC cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2404602 0.735 rs2280306 chr15:76652258 C/G cg23625390 chr15:77176239 SCAPER -0.48 -8.0 -0.4 2.01e-14 Blood metabolite levels; LIHC cis rs11758351 1.000 rs3734530 chr6:26195408 G/C cg03854865 chr6:26224070 HIST1H3E 0.63 7.07 0.36 8.82e-12 Gout;Renal underexcretion gout; LIHC cis rs8023580 1.000 rs4984512 chr15:96704448 T/G cg01739960 chr15:96715164 NA 0.36 5.79 0.3 1.62e-8 Sex hormone-binding globulin levels; LIHC cis rs919433 0.889 rs10931782 chr2:198211579 G/A cg03934865 chr2:198174659 NA -0.57 -8.94 -0.44 2.54e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8044995 0.563 rs61602448 chr16:68377520 C/T cg05110241 chr16:68378359 PRMT7 -0.88 -9.93 -0.47 1.39e-20 Schizophrenia; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg27432699 chr2:27873401 GPN1 -0.54 -7.69 -0.38 1.5700000000000001e-13 Total body bone mineral density; LIHC cis rs10463316 0.862 rs11747047 chr5:150777953 C/T cg03212797 chr5:150827313 SLC36A1 -0.48 -7.33 -0.37 1.63e-12 Metabolite levels (Pyroglutamine); LIHC cis rs11792861 0.926 rs72607171 chr9:111837776 T/C cg05043794 chr9:111880884 C9orf5 -0.3 -6.94 -0.35 1.97e-11 Menarche (age at onset); LIHC cis rs1348850 0.914 rs4893957 chr2:178380409 A/G cg27490568 chr2:178487706 NA 0.36 5.75 0.3 1.98e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs2727020 0.754 rs1851990 chr11:49413336 C/T cg18944383 chr4:111397179 ENPEP 0.31 7.29 0.37 2.14e-12 Coronary artery disease; LIHC cis rs6582630 0.555 rs2090785 chr12:38424342 G/A cg26384229 chr12:38710491 ALG10B 0.61 8.48 0.42 6.79e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs1577917 0.917 rs2084293 chr6:86566002 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.22 -0.41 4.25e-15 Response to antipsychotic treatment; LIHC cis rs7903847 0.642 rs2297668 chr10:99160046 C/T cg06359132 chr10:99160096 RRP12 -0.41 -6.44 -0.33 3.99e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs17102423 0.723 rs11158573 chr14:65579370 A/G cg11161011 chr14:65562177 MAX -0.57 -7.91 -0.39 3.55e-14 Obesity-related traits; LIHC cis rs2204008 0.614 rs4578492 chr12:38036350 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.75 0.3 1.99e-8 Bladder cancer; LIHC cis rs2073300 1.000 rs6036424 chr20:23459976 A/C cg12062639 chr20:23401060 NAPB -0.76 -9.49 -0.46 4.23e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1707322 1.000 rs3922886 chr1:46473902 A/T cg06784218 chr1:46089804 CCDC17 0.37 6.65 0.34 1.14e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs763121 0.853 rs8138996 chr22:39047435 G/T cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs17125944 0.686 rs7145242 chr14:53349842 G/A cg00686598 chr14:53173677 PSMC6 -0.77 -8.63 -0.42 2.29e-16 Alzheimer's disease (late onset); LIHC cis rs4819052 0.808 rs2838825 chr21:46655651 C/T cg11663144 chr21:46675770 NA -0.33 -5.93 -0.31 7.52e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1577917 0.958 rs12205492 chr6:86475976 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.44 -0.37 8.14e-13 Response to antipsychotic treatment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06905970 chr19:41222748 ADCK4;ITPKC 0.39 6.14 0.32 2.32e-9 Lung function (FEV1/FVC); LIHC cis rs6570726 0.764 rs9322028 chr6:145895797 G/T cg05347473 chr6:146136440 FBXO30 0.39 6.24 0.32 1.3e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg11987759 chr7:65425863 GUSB -0.39 -6.17 -0.32 1.88e-9 Calcium levels; LIHC cis rs240764 0.853 rs11155498 chr6:101019551 G/C cg09795085 chr6:101329169 ASCC3 -0.49 -6.61 -0.34 1.49e-10 Neuroticism; LIHC cis rs801193 1.000 rs4717319 chr7:66242593 A/G cg11764359 chr7:65958608 NA 0.71 10.6 0.5 6.78e-23 Aortic root size; LIHC cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg16434002 chr17:42200994 HDAC5 -0.53 -7.7 -0.38 1.52e-13 Total body bone mineral density; LIHC cis rs7829975 0.742 rs1533058 chr8:8685190 A/G cg06636001 chr8:8085503 FLJ10661 0.41 6.42 0.33 4.44e-10 Mood instability; LIHC cis rs372883 0.600 rs2832295 chr21:30739843 C/T cg08807101 chr21:30365312 RNF160 0.53 6.1 0.31 2.86e-9 Pancreatic cancer; LIHC cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg05564831 chr3:52568323 NT5DC2 0.36 5.81 0.3 1.45e-8 Bipolar disorder; LIHC cis rs2836950 0.501 rs11088470 chr21:40689162 A/G cg11890956 chr21:40555474 PSMG1 -0.42 -6.74 -0.34 6.64e-11 Menarche (age at onset); LIHC cis rs10845606 0.781 rs7972866 chr12:12828320 C/T cg04607235 chr12:12878440 APOLD1 -0.47 -6.64 -0.34 1.23e-10 Systemic lupus erythematosus; LIHC cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg05590025 chr7:65112418 INTS4L2 -0.63 -6.87 -0.35 3.1e-11 Diabetic kidney disease; LIHC cis rs4820294 1.000 rs739139 chr22:38067011 C/G cg10587741 chr22:38071170 LGALS1 0.73 12.78 0.57 7.83e-31 Fat distribution (HIV); LIHC cis rs727563 0.580 rs202626 chr22:41847190 C/A cg03806693 chr22:41940476 POLR3H 1.05 12.79 0.57 7.17e-31 Crohn's disease;Inflammatory bowel disease; LIHC cis rs6840360 0.571 rs2407069 chr4:152533201 G/A cg22705602 chr4:152727874 NA -0.32 -6.35 -0.32 6.8e-10 Intelligence (multi-trait analysis); LIHC cis rs870825 0.616 rs35818632 chr4:185649661 G/T cg04058563 chr4:185651563 MLF1IP 0.77 7.53 0.38 4.6e-13 Blood protein levels; LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg18306943 chr3:40428807 ENTPD3 0.41 7.12 0.36 6.48e-12 Renal cell carcinoma; LIHC cis rs7089973 0.604 rs35319791 chr10:116602296 C/A cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs17685 0.725 rs4476928 chr7:75642107 C/A cg04592579 chr7:75616294 TMEM120A -0.4 -6.85 -0.35 3.34e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg11890956 chr21:40555474 PSMG1 0.56 9.34 0.45 1.23e-18 Cognitive function; LIHC cis rs2412488 0.850 rs9312639 chr4:54226228 A/T cg22241045 chr4:54363911 LNX1 -0.38 -6.21 -0.32 1.56e-9 DNA methylation (variation); LIHC cis rs7085104 0.660 rs7902804 chr10:104585405 A/T cg15744005 chr10:104629667 AS3MT -0.36 -7.72 -0.39 1.27e-13 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs3820068 0.705 rs41486146 chr1:15900517 A/G cg17385448 chr1:15911702 AGMAT -0.36 -5.78 -0.3 1.7e-8 Systolic blood pressure; LIHC cis rs17685 0.796 rs3757594 chr7:75678644 G/A cg04610667 chr7:75704037 NA 0.35 6.23 0.32 1.34e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7617480 0.648 rs4858830 chr3:48734002 T/C cg07636037 chr3:49044803 WDR6 0.71 8.14 0.4 7.58e-15 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs2439831 1.000 rs101094 chr15:43787322 C/G cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.34e-9 Lung cancer in ever smokers; LIHC cis rs17685 0.712 rs4732578 chr7:75721532 A/G cg04610667 chr7:75704037 NA -0.33 -5.94 -0.31 6.93e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg16405210 chr4:1374714 KIAA1530 0.78 11.25 0.52 3.36e-25 Longevity; LIHC cis rs238295 0.766 rs6139759 chr20:5511742 A/G cg24001556 chr20:5591874 RP5-1022P6.2 0.42 5.71 0.3 2.43e-8 Occipital cortical area (total cortical area interaction); LIHC cis rs3741798 1.000 rs77559638 chr12:12499909 T/A cg08615371 chr12:12503544 MANSC1 0.9 7.29 0.37 2.18e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs7131987 0.845 rs7299861 chr12:29409667 G/A cg14222432 chr12:29376421 FAR2 0.36 7.05 0.36 9.82e-12 QT interval; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21989094 chr19:39421295 MRPS12;SARS2 0.43 6.49 0.33 2.95e-10 Cognitive function; LIHC cis rs694739 1.000 rs11231757 chr11:64106317 C/T cg23796481 chr11:64053134 BAD;GPR137 0.6 8.36 0.41 1.59e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25152348 chr22:50946712 NCAPH2;LMF2 -0.51 -7.5 -0.38 5.42e-13 Cognitive function; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg09367891 chr1:107599246 PRMT6 0.65 10.87 0.51 7.89e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4660306 0.677 rs781062 chr1:45932738 T/A cg03123370 chr1:45965343 CCDC163P;MMACHC 0.62 6.54 0.33 2.24e-10 Homocysteine levels; LIHC cis rs10508774 0.866 rs72784062 chr10:33194851 A/G cg01819863 chr10:32635814 EPC1 0.64 5.77 0.3 1.74e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2749592 0.505 rs7915670 chr10:37870212 T/C cg25427524 chr10:38739819 LOC399744 0.56 10.16 0.48 2.36e-21 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs12752401 0.867 rs67349818 chr1:103030560 T/C cg17681729 chr19:740608 PALM 0.44 6.24 0.32 1.27e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs7551222 0.752 rs12133735 chr1:204556836 G/T cg20240347 chr1:204465584 NA -0.31 -6.34 -0.32 7.1e-10 Schizophrenia; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg13395646 chr4:1353034 KIAA1530 -0.44 -6.26 -0.32 1.13e-9 Longevity; LIHC cis rs3845702 0.736 rs3845701 chr2:180826781 A/G cg01881094 chr2:180872142 CWC22 -1.13 -10.41 -0.49 3.17e-22 Schizophrenia; LIHC cis rs7772486 0.875 rs9322043 chr6:146352690 A/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.24 -0.32 1.32e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs832187 1.000 rs832187 chr3:63833050 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.55 8.02 0.4 1.69e-14 Schizophrenia; LIHC cis rs7818688 0.614 rs12056517 chr8:95877285 C/T cg16049864 chr8:95962084 TP53INP1 0.53 5.99 0.31 5.28e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6723226 0.882 rs13035097 chr2:32836362 A/G cg02381751 chr2:32503542 YIPF4 -0.7 -10.14 -0.48 2.74e-21 Intelligence (multi-trait analysis); LIHC cis rs12142240 0.698 rs68083747 chr1:46807416 T/G cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs7089973 0.604 rs11196947 chr10:116601372 G/A cg03647239 chr10:116582469 FAM160B1 0.45 6.67 0.34 1.02e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7191700 0.601 rs243329 chr16:11352313 A/T cg00044050 chr16:11439710 C16orf75 0.42 5.8 0.3 1.53e-8 Multiple sclerosis; LIHC cis rs56235845 0.694 rs4976643 chr5:176760227 A/C cg17509989 chr5:176798049 RGS14 0.6 7.71 0.38 1.37e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs6793245 0.810 rs1805126 chr3:38592406 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.47 6.97 0.35 1.68e-11 QT interval; LIHC cis rs7582720 1.000 rs72936846 chr2:203774734 G/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9733 0.596 rs2065900 chr1:150652202 A/G cg17724175 chr1:150552817 MCL1 0.47 9.51 0.46 3.45e-19 Tonsillectomy; LIHC cis rs3770081 1.000 rs76052260 chr2:86328727 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.88 -9.26 -0.45 2.39e-18 Facial emotion recognition (sad faces); LIHC cis rs2797160 1.000 rs1832980 chr6:125997444 T/G cg05901451 chr6:126070800 HEY2 -0.41 -6.95 -0.35 1.82e-11 Endometrial cancer; LIHC cis rs244293 0.965 rs2787488 chr17:53208151 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs243505 0.691 rs243486 chr7:148448221 A/C cg09806900 chr7:148480153 CUL1 -0.43 -6.01 -0.31 4.89e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4555082 0.874 rs2816621 chr14:105732762 A/T cg13114125 chr14:105738426 BRF1 -0.74 -9.59 -0.46 1.96e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg02290350 chr8:58132656 NA 0.47 9.29 0.45 1.8e-18 Developmental language disorder (linguistic errors); LIHC cis rs6570726 0.738 rs4495284 chr6:145916617 T/A cg23711669 chr6:146136114 FBXO30 0.65 10.91 0.51 5.77e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2075371 1.000 rs2598297 chr7:133993001 T/G cg20476274 chr7:133979776 SLC35B4 0.75 12.17 0.55 1.53e-28 Mean platelet volume; LIHC cis rs611744 0.967 rs651814 chr8:109196571 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs6582630 0.502 rs11181214 chr12:38298313 C/A cg26384229 chr12:38710491 ALG10B 0.6 8.19 0.4 5.23e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs55883249 0.957 rs10495572 chr2:9734859 C/G cg23886495 chr2:9695866 ADAM17 -0.74 -6.79 -0.34 4.9e-11 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; LIHC cis rs10792665 0.611 rs6592088 chr11:82624487 G/A cg24227371 chr11:82718527 RAB30 -0.27 -6.13 -0.31 2.41e-9 Obesity-related traits; LIHC cis rs9733 0.536 rs6661415 chr1:150635869 G/A cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs10779751 0.960 rs2076657 chr1:11318763 C/G cg08854313 chr1:11322531 MTOR 0.87 15.77 0.65 1.66e-42 Body mass index; LIHC cis rs9399135 0.967 rs4896125 chr6:135342569 C/T cg24558204 chr6:135376177 HBS1L 0.42 6.82 0.35 4.14e-11 Red blood cell count; LIHC cis rs9303401 0.659 rs35082010 chr17:56936867 A/G cg25039879 chr17:56429692 SUPT4H1 0.79 8.95 0.44 2.32e-17 Cognitive test performance; LIHC trans rs941408 0.928 rs2260414 chr19:2796316 G/A cg22153745 chr1:153894579 GATAD2B -0.39 -6.04 -0.31 4.06e-9 Total cholesterol levels; LIHC cis rs763121 0.853 rs4821809 chr22:39065743 G/C cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs6089584 0.888 rs2892060 chr20:60617955 G/T cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC cis rs10751667 0.560 rs10902265 chr11:1003642 G/A cg10932868 chr11:921992 NA 0.34 6.42 0.33 4.67e-10 Alzheimer's disease (late onset); LIHC cis rs2073300 0.609 rs6137931 chr20:23376875 G/C cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs116095464 0.614 rs78905930 chr5:246560 G/A cg22496380 chr5:211416 CCDC127 -1.07 -11.09 -0.51 1.23e-24 Breast cancer; LIHC trans rs10805346 0.501 rs4604059 chr4:10115065 C/T cg06175025 chr14:78082992 SPTLC2 0.42 6.12 0.31 2.51e-9 Urate levels in overweight individuals;Urate levels in obese individuals; LIHC cis rs9902453 0.619 rs2617866 chr17:28076217 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -12.72 -0.57 1.27e-30 Coffee consumption (cups per day); LIHC cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.48 -0.38 6.22e-13 Bipolar disorder; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg22882523 chr8:145107012 OPLAH -0.29 -6.34 -0.32 7.17e-10 Systolic blood pressure; LIHC cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg20469419 chr4:1232170 CTBP1 -0.32 -5.82 -0.3 1.32e-8 Obesity-related traits; LIHC cis rs7945705 0.747 rs1123936 chr11:9003306 A/G cg12365402 chr11:9010492 NRIP3 -0.29 -7.8 -0.39 7.62e-14 Hemoglobin concentration; LIHC cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg23982607 chr1:1823379 GNB1 -0.75 -15.34 -0.64 8.88e-41 Body mass index; LIHC cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.27e-12 Bipolar disorder; LIHC cis rs782590 0.967 rs58003472 chr2:55797507 T/C cg03859395 chr2:55845619 SMEK2 0.85 15.02 0.63 1.56e-39 Metabolic syndrome; LIHC trans rs1005277 0.579 rs2472176 chr10:38382921 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs4555082 0.834 rs2816623 chr14:105733295 G/A cg06808227 chr14:105710500 BRF1 -0.49 -6.05 -0.31 3.79e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.06 0.44 1.02e-17 Electroencephalogram traits; LIHC cis rs2576037 0.899 rs2571034 chr18:44578565 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.48 -7.09 -0.36 7.75e-12 Personality dimensions; LIHC cis rs2224391 0.784 rs35048711 chr6:5262235 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -5.96 -0.31 6.36e-9 Height; LIHC cis rs763121 0.962 rs2071887 chr22:38879010 A/T cg14440974 chr22:39074834 NA -0.36 -5.98 -0.31 5.65e-9 Menopause (age at onset); LIHC cis rs8062405 1.000 rs4788095 chr16:28831359 T/C cg00204512 chr16:28754710 NA 0.35 6.4 0.33 4.98e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs801193 1.000 rs4717310 chr7:66161007 C/T cg26939375 chr7:64535504 NA 0.42 6.77 0.34 5.56e-11 Aortic root size; LIHC cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg06634786 chr22:41940651 POLR3H -0.77 -8.37 -0.41 1.53e-15 Vitiligo; LIHC cis rs722599 0.501 rs7158047 chr14:75388803 G/A cg11812906 chr14:75593930 NEK9 0.46 7.8 0.39 7.74e-14 IgG glycosylation; LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.33 0.32 7.68e-10 Total body bone mineral density; LIHC cis rs7408868 1.000 rs7247906 chr19:15271135 T/G cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg02931644 chr1:25747376 RHCE 0.35 7.43 0.37 9e-13 Plateletcrit;Mean corpuscular volume; LIHC cis rs8114671 0.839 rs2104084 chr20:33649217 G/C cg07148914 chr20:33460835 GGT7 -0.56 -8.45 -0.42 8.7e-16 Height; LIHC trans rs2727020 0.521 rs7126835 chr11:49594658 T/C cg03929089 chr4:120376271 NA -0.69 -10.15 -0.48 2.57e-21 Coronary artery disease; LIHC cis rs7116495 0.609 rs2276384 chr11:71701523 A/G cg26138937 chr11:71823887 C11orf51 1.19 9.95 0.47 1.14e-20 Severe influenza A (H1N1) infection; LIHC cis rs317689 0.718 rs160827 chr12:69770147 G/A cg20891283 chr12:69753455 YEATS4 0.69 10.98 0.51 3.03e-24 Response to diuretic therapy; LIHC cis rs6582630 0.555 rs10880611 chr12:38509316 C/G cg26384229 chr12:38710491 ALG10B 0.7 9.97 0.47 1.01e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs4638749 0.677 rs2198471 chr2:108844069 C/T cg25838818 chr2:108905173 SULT1C2 -0.4 -7.03 -0.36 1.15e-11 Blood pressure; LIHC cis rs3020736 0.500 rs6002597 chr22:42488160 C/A cg15557168 chr22:42548783 NA 0.46 7.08 0.36 8.47e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs17818399 0.541 rs12712976 chr2:46786491 G/A cg02822958 chr2:46747628 ATP6V1E2 0.42 6.64 0.34 1.27e-10 Height; LIHC trans rs7504990 0.722 rs34923505 chr18:50372170 G/A cg08535148 chr4:26321143 RBPJ 0.56 6.99 0.35 1.42e-11 Gallbladder cancer; LIHC cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.6 -6.16 -0.32 2.05e-9 Diastolic blood pressure; LIHC cis rs240764 0.658 rs2050549 chr6:101216645 A/G cg09795085 chr6:101329169 ASCC3 -0.41 -5.73 -0.3 2.19e-8 Neuroticism; LIHC cis rs864643 1.000 rs1340223 chr3:39549699 T/G cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg14004847 chr7:1930337 MAD1L1 -0.53 -8.02 -0.4 1.67e-14 Bipolar disorder and schizophrenia; LIHC trans rs4566357 0.615 rs12328876 chr2:227918899 G/T cg16088116 chr21:44841560 SIK1 -0.42 -6.34 -0.32 7.23e-10 Coronary artery disease; LIHC cis rs5753037 0.639 rs5997534 chr22:30220190 G/A cg01021169 chr22:30184971 ASCC2 -0.41 -8.2 -0.41 4.77e-15 Type 1 diabetes; LIHC cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.65 -10.47 -0.49 1.93e-22 Colorectal cancer; LIHC cis rs2806561 0.704 rs674386 chr1:23521835 G/A cg12483005 chr1:23474871 LUZP1 0.47 7.24 0.36 3.01e-12 Height; LIHC cis rs36051895 0.589 rs62543574 chr9:5204090 A/T cg02405213 chr9:5042618 JAK2 -0.64 -10.69 -0.5 3.32e-23 Pediatric autoimmune diseases; LIHC cis rs8180040 0.701 rs7625067 chr3:47095305 T/C cg27129171 chr3:47204927 SETD2 0.68 11.97 0.54 7.99e-28 Colorectal cancer; LIHC cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.49 0.46 3.97e-19 Bipolar disorder; LIHC cis rs11673344 0.504 rs2595555 chr19:37491121 C/T cg27390819 chr19:37464633 NA -0.47 -6.15 -0.32 2.22e-9 Obesity-related traits; LIHC cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg21724239 chr8:58056113 NA 0.57 7.02 0.35 1.19e-11 Developmental language disorder (linguistic errors); LIHC cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.43 5.77 0.3 1.82e-8 Electroencephalogram traits; LIHC cis rs1348850 0.914 rs12612857 chr2:178467144 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.78 11.42 0.53 8.51e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10744422 1.000 rs3852536 chr12:123333824 C/T cg22842854 chr12:123319900 HIP1R -0.73 -9.7 -0.46 8.21e-20 Schizophrenia; LIHC cis rs763014 0.932 rs2384972 chr16:674424 G/A cg07343612 chr16:622815 PIGQ -0.87 -15.07 -0.63 1.04e-39 Height; LIHC cis rs9818758 0.607 rs9311439 chr3:49310408 A/G cg00383909 chr3:49044727 WDR6 0.77 6.32 0.32 8.14e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7937682 0.921 rs1944119 chr11:111436387 A/G cg09085632 chr11:111637200 PPP2R1B 0.83 9.56 0.46 2.43e-19 Primary sclerosing cholangitis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24452069 chr19:4867631 PLIN3 0.48 6.16 0.32 2e-9 Lung function (FEV1/FVC); LIHC cis rs9303401 0.659 rs7210432 chr17:56668170 C/T cg25039879 chr17:56429692 SUPT4H1 0.79 8.97 0.44 1.98e-17 Cognitive test performance; LIHC cis rs921968 0.541 rs6720403 chr2:219294258 A/C cg02985541 chr2:219472218 PLCD4 -0.41 -6.55 -0.33 2.13e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.49 -7.72 -0.39 1.27e-13 Prudent dietary pattern; LIHC cis rs826838 0.935 rs1160162 chr12:38959795 G/A cg13010199 chr12:38710504 ALG10B 0.57 7.08 0.36 8.35e-12 Heart rate; LIHC cis rs12200782 0.505 rs1535275 chr6:26520767 G/C cg11502198 chr6:26597334 ABT1 0.79 9.37 0.45 9.99e-19 Small cell lung carcinoma; LIHC cis rs600806 0.778 rs6693932 chr1:110003575 T/C cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.16 -0.32 2.08e-9 Intelligence (multi-trait analysis); LIHC cis rs9733 0.527 rs11204694 chr1:150653391 G/A cg15448220 chr1:150897856 SETDB1 0.43 6.73 0.34 6.98e-11 Tonsillectomy; LIHC cis rs4819052 0.851 rs28622522 chr21:46676599 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.41 0.52 9.28e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.34 0.56 3.48e-29 Prudent dietary pattern; LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg02993280 chr1:107599747 PRMT6 -0.69 -11.16 -0.52 6.98e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9486719 0.947 rs12194971 chr6:96911073 T/C cg06623918 chr6:96969491 KIAA0776 -0.65 -6.62 -0.34 1.36e-10 Migraine;Coronary artery disease; LIHC cis rs7191700 0.673 rs12325495 chr16:11418328 C/T cg00044050 chr16:11439710 C16orf75 0.51 7.54 0.38 4.41e-13 Multiple sclerosis; LIHC cis rs875971 0.862 rs4718383 chr7:66108409 T/C cg18876405 chr7:65276391 NA -0.32 -5.86 -0.3 1.08e-8 Aortic root size; LIHC cis rs6461049 0.800 rs2398706 chr7:2156338 A/T cg04267008 chr7:1944627 MAD1L1 -0.48 -7.31 -0.37 1.86e-12 Schizophrenia; LIHC cis rs477692 0.685 rs551491 chr10:131397821 G/A cg05714579 chr10:131428358 MGMT 0.45 7.64 0.38 2.24e-13 Response to temozolomide; LIHC cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg06481639 chr22:41940642 POLR3H -0.72 -6.74 -0.34 6.5500000000000006e-11 Vitiligo; LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.11 -0.31 2.69e-9 Menopause (age at onset); LIHC cis rs7937682 0.793 rs7130440 chr11:111417779 A/G cg09085632 chr11:111637200 PPP2R1B 0.68 7.94 0.39 2.98e-14 Primary sclerosing cholangitis; LIHC cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -11.17 -0.52 6.65e-25 Platelet count; LIHC cis rs3791556 0.842 rs55840142 chr2:240106884 G/A cg03281426 chr2:240109471 HDAC4 0.39 6.18 0.32 1.87e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4407350 1.000 rs5764886 chr22:44925334 C/T cg11695653 chr22:44894386 LDOC1L -0.37 -6.02 -0.31 4.39e-9 Intelligence (multi-trait analysis); LIHC cis rs10508774 0.866 rs11009070 chr10:33054285 C/A cg01819863 chr10:32635814 EPC1 0.63 5.78 0.3 1.68e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs782590 0.967 rs782592 chr2:55843875 T/A cg18811423 chr2:55921094 PNPT1 0.79 11.84 0.54 2.4200000000000002e-27 Metabolic syndrome; LIHC cis rs875971 0.662 rs448725 chr7:65514628 A/G cg18876405 chr7:65276391 NA 0.42 7.39 0.37 1.16e-12 Aortic root size; LIHC cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg01788221 chr16:89496183 ANKRD11 0.41 6.51 0.33 2.69e-10 Multiple myeloma (IgH translocation); LIHC trans rs8073060 0.586 rs226089 chr17:34016935 C/T cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25789201 chr7:72395803 POM121 0.46 6.42 0.33 4.53e-10 Pancreatic cancer; LIHC cis rs11030122 0.702 rs1013351 chr11:3952303 A/T cg18678763 chr11:4115507 RRM1 -0.58 -8.57 -0.42 3.57e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs965469 0.779 rs6051683 chr20:3237822 G/C cg25506879 chr20:3388711 C20orf194 -0.52 -6.33 -0.32 7.92e-10 IFN-related cytopenia; LIHC cis rs67311347 0.605 rs1880762 chr3:40283215 A/G cg10755058 chr3:40428713 ENTPD3 0.37 6.21 0.32 1.52e-9 Renal cell carcinoma; LIHC cis rs17376456 0.825 rs17372649 chr5:93126096 C/G cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs9811920 0.609 rs2452320 chr3:99645216 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs2839627 0.638 rs7276320 chr21:44269588 A/G cg18192155 chr21:44258298 NA -0.48 -6.3 -0.32 9.02e-10 Information processing speed; LIHC cis rs898097 0.690 rs12452304 chr17:80811659 G/A cg15664640 chr17:80829946 TBCD -0.77 -12.71 -0.57 1.44e-30 Breast cancer; LIHC cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg16405210 chr4:1374714 KIAA1530 -0.94 -15.95 -0.65 3.21e-43 Longevity; LIHC cis rs3809566 1.000 rs10851721 chr15:63332383 T/C cg05771511 chr15:63340396 TPM1 0.47 6.97 0.35 1.63e-11 Platelet count; LIHC cis rs2050392 0.517 rs687036 chr10:30761249 G/A cg25182066 chr10:30743637 MAP3K8 -0.67 -11.05 -0.51 1.75e-24 Inflammatory bowel disease; LIHC cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg05527609 chr1:210001259 C1orf107 -0.41 -5.99 -0.31 5.31e-9 Cleft lip with or without cleft palate; LIHC cis rs74181299 0.750 rs2723067 chr2:65277951 A/G cg05010058 chr2:65284262 CEP68 0.35 5.94 0.31 7.07e-9 Pulse pressure; LIHC cis rs10078 0.559 rs2671891 chr5:456386 A/G cg08916839 chr5:415575 AHRR 0.61 12.64 0.56 2.53e-30 Fat distribution (HIV); LIHC cis rs2153535 0.547 rs9505475 chr6:8542890 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.51 0.42 5.35e-16 Motion sickness; LIHC cis rs1580019 0.563 rs2392071 chr7:32572536 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.61 8.99 0.44 1.75e-17 Cognitive ability; LIHC cis rs9916302 0.707 rs11078903 chr17:37631924 G/A cg03013999 chr17:37608204 MED1 0.36 5.91 0.3 8.43e-9 Glomerular filtration rate (creatinine); LIHC cis rs6598955 0.670 rs7520517 chr1:26556385 A/C cg00852783 chr1:26633632 UBXN11 0.48 8.2 0.41 4.83e-15 Obesity-related traits; LIHC cis rs8078723 0.738 rs3816472 chr17:38142677 A/C cg17467752 chr17:38218738 THRA -0.6 -10.18 -0.48 1.93e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg16405210 chr4:1374714 KIAA1530 0.43 6.41 0.33 4.81e-10 Obesity-related traits; LIHC trans rs8002861 0.935 rs4101376 chr13:44469835 C/T cg17145862 chr1:211918768 LPGAT1 -0.67 -13.21 -0.58 1.8e-32 Leprosy; LIHC cis rs9814567 1.000 rs1880377 chr3:134270468 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs796364 1.000 rs71424239 chr2:200725473 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.7 -6.37 -0.33 6.02e-10 Schizophrenia; LIHC cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg10360323 chr17:41437877 NA 0.4 5.96 0.31 6.14e-9 Menopause (age at onset); LIHC cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs208520 0.690 rs12189780 chr6:66759619 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.79 9.08 0.44 8.83e-18 Exhaled nitric oxide output; LIHC cis rs1018836 0.773 rs7837109 chr8:91639178 C/T cg16814680 chr8:91681699 NA -0.63 -10.01 -0.48 7.62e-21 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.76e-9 Menopause (age at onset); LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg06873352 chr17:61820015 STRADA 0.54 8.27 0.41 3.07e-15 Height; LIHC cis rs7937682 0.889 rs10749984 chr11:111492861 T/C cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs559928 0.549 rs57831436 chr11:64007297 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.71 6.18 0.32 1.82e-9 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg23131131 chr22:24373011 LOC391322 -0.64 -9.52 -0.46 3.19e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2777491 0.915 rs28526381 chr15:41621842 A/C cg18705301 chr15:41695430 NDUFAF1 -0.55 -8.15 -0.4 7.18e-15 Ulcerative colitis; LIHC cis rs1003719 0.713 rs7277150 chr21:38490006 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.94 0.54 1.01e-27 Eye color traits; LIHC cis rs7666738 0.830 rs1869897 chr4:98730997 C/T cg05340658 chr4:99064831 C4orf37 0.64 11.59 0.53 2.03e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs6089584 0.566 rs6061963 chr20:60607480 C/G cg06108461 chr20:60628389 TAF4 -0.66 -9.29 -0.45 1.81e-18 Body mass index; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg25951811 chr14:96858416 AK7 0.38 6.08 0.31 3.19e-9 Calcium levels; LIHC cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg00750074 chr16:89608354 SPG7 -0.39 -5.89 -0.3 9.06e-9 Multiple myeloma (IgH translocation); LIHC cis rs16870629 0.567 rs35661060 chr5:1060379 G/A cg08382946 chr5:1082689 SLC12A7 -0.43 -6.29 -0.32 9.61e-10 QT interval; LIHC cis rs12701220 0.655 rs12702117 chr7:1148702 T/C cg18765753 chr7:1198926 ZFAND2A -0.41 -5.77 -0.3 1.82e-8 Bronchopulmonary dysplasia; LIHC cis rs600806 0.854 rs367586 chr1:109850122 C/A cg23091122 chr1:110024289 SYPL2 -0.45 -5.71 -0.3 2.44e-8 Intelligence (multi-trait analysis); LIHC cis rs782590 0.934 rs17369191 chr2:55757885 T/C cg03859395 chr2:55845619 SMEK2 0.9 15.35 0.64 8.28e-41 Metabolic syndrome; LIHC cis rs9611565 0.571 rs2050032 chr22:42152429 C/T cg03806693 chr22:41940476 POLR3H 0.87 9.48 0.46 4.34e-19 Vitiligo; LIHC cis rs35306767 0.714 rs12777800 chr10:1070361 G/A cg20503657 chr10:835505 NA 0.7 6.73 0.34 7.09e-11 Eosinophil percentage of granulocytes; LIHC cis rs1348850 0.540 rs10172355 chr2:178443225 A/G cg27490568 chr2:178487706 NA 1.02 12.11 0.55 2.4e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs66887589 0.776 rs10518337 chr4:120574874 A/C cg09307838 chr4:120376055 NA -0.41 -6.12 -0.31 2.56e-9 Diastolic blood pressure; LIHC cis rs34779708 0.897 rs34481177 chr10:35380913 C/T cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs798554 0.704 rs709282 chr7:2769921 G/A cg19717773 chr7:2847554 GNA12 -0.39 -6.9 -0.35 2.52e-11 Height; LIHC cis rs9814567 0.964 rs4539979 chr3:134287597 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.66 -12.22 -0.55 9.28e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg07424592 chr7:64974309 NA 0.83 9.5 0.46 3.78e-19 Diabetic kidney disease; LIHC cis rs10779751 0.770 rs12041740 chr1:11236524 G/A cg08854313 chr1:11322531 MTOR 0.84 14.74 0.62 1.99e-38 Body mass index; LIHC cis rs796364 1.000 rs281774 chr2:200814572 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.77 9.43 0.45 6.44e-19 Schizophrenia; LIHC cis rs3859192 0.577 rs25645 chr17:38173143 G/A cg17467752 chr17:38218738 THRA -0.5 -8.49 -0.42 6.42e-16 White blood cell count; LIHC cis rs10504073 0.647 rs6997703 chr8:49998364 T/C cg00325661 chr8:49890786 NA 0.32 7.35 0.37 1.43e-12 Blood metabolite ratios; LIHC cis rs250677 0.652 rs250670 chr5:148446646 G/T cg12140854 chr5:148520817 ABLIM3 -0.46 -6.2 -0.32 1.66e-9 Breast cancer; LIHC cis rs7927592 0.913 rs10896330 chr11:68254998 A/G cg16797656 chr11:68205561 LRP5 0.54 8.53 0.42 4.69e-16 Total body bone mineral density; LIHC cis rs4808199 0.948 rs1859287 chr19:19422187 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.55 8.05 0.4 1.43e-14 Nonalcoholic fatty liver disease; LIHC cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg08219700 chr8:58056026 NA 0.52 6.7 0.34 8.83e-11 Developmental language disorder (linguistic errors); LIHC cis rs1712517 0.771 rs10883857 chr10:105127587 A/C cg05636881 chr10:105038444 INA -0.48 -7.38 -0.37 1.21e-12 Migraine; LIHC cis rs7560272 0.695 rs780394 chr2:73700930 A/G cg20560298 chr2:73613845 ALMS1 0.36 5.83 0.3 1.26e-8 Schizophrenia; LIHC cis rs8062405 0.723 rs12445744 chr16:28588395 A/C cg07382826 chr16:28625726 SULT1A1 0.5 7.74 0.39 1.13e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11167764 1.000 rs3761757 chr5:141488219 A/C cg23435118 chr5:141488016 NDFIP1 -0.43 -6.02 -0.31 4.41e-9 Crohn's disease; LIHC cis rs7116495 0.609 rs7942626 chr11:71703849 G/A cg26138937 chr11:71823887 C11orf51 -1.28 -10.45 -0.49 2.31e-22 Severe influenza A (H1N1) infection; LIHC cis rs2952156 0.959 rs1495101 chr17:37832103 C/A cg00129232 chr17:37814104 STARD3 -0.52 -9.47 -0.46 4.75e-19 Asthma; LIHC cis rs611744 0.967 rs635219 chr8:109229243 C/T cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs798554 0.686 rs2644298 chr7:2858448 G/C cg19346786 chr7:2764209 NA -0.36 -5.78 -0.3 1.65e-8 Height; LIHC cis rs4930103 0.904 rs4929984 chr11:2024683 A/C cg06197492 chr11:2016605 H19 -0.38 -6.11 -0.31 2.68e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs9583531 0.600 rs2119479 chr13:111371181 A/C cg15841412 chr13:111365552 ING1 0.48 6.04 0.31 4.06e-9 Coronary artery disease; LIHC trans rs1814175 0.615 rs11040654 chr11:49939485 T/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs9814567 1.000 rs13090969 chr3:134307257 C/A cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.9 0.3 8.68e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs769267 0.965 rs2315025 chr19:19426609 C/T cg03709012 chr19:19516395 GATAD2A 0.91 15.49 0.64 2.32e-41 Tonsillectomy; LIHC cis rs9921222 0.565 rs1805105 chr16:396264 A/G cg26944245 chr16:421049 TMEM8A;MRPL28 0.54 10.82 0.51 1.13e-23 Bone mineral density (spine);Bone mineral density; LIHC cis rs7707921 0.881 rs57621982 chr5:81406770 C/T cg15871215 chr5:81402204 ATG10 -0.61 -5.92 -0.3 7.81e-9 Breast cancer; LIHC cis rs644799 1.000 rs593665 chr11:95574302 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.44 0.66 3.7e-45 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg23782820 chr8:58130467 NA 0.33 5.95 0.31 6.66e-9 Developmental language disorder (linguistic errors); LIHC cis rs6120849 0.707 rs3746444 chr20:33578251 A/G cg06115741 chr20:33292138 TP53INP2 0.49 5.83 0.3 1.3e-8 Protein C levels; LIHC cis rs798554 0.679 rs1639066 chr7:2892972 A/G cg13628971 chr7:2884303 GNA12 0.6 10.2 0.48 1.62e-21 Height; LIHC cis rs597539 0.652 rs507520 chr11:68666054 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.39 0.49 3.81e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs4660306 1.000 rs4660306 chr1:45978675 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.53 6.8 0.34 4.8e-11 Homocysteine levels; LIHC cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg10360323 chr17:41437877 NA 0.4 6.05 0.31 3.83e-9 Menopause (age at onset); LIHC cis rs2439831 0.717 rs9806227 chr15:43680115 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.9 16.43 0.66 4.17e-45 Lung cancer in ever smokers; LIHC cis rs7224737 1.000 rs7219220 chr17:40294280 T/C cg20291162 chr17:40259547 DHX58 -0.4 -6.38 -0.33 5.82e-10 Fibrinogen levels; LIHC cis rs727505 1.000 rs1541418 chr7:124448672 A/G cg23710748 chr7:124431027 NA -0.33 -5.83 -0.3 1.32e-8 Lewy body disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05531134 chr21:19192027 C21orf91 -0.51 -7.05 -0.36 9.96e-12 Pancreatic cancer; LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg00612595 chr21:47717864 NA -0.38 -6.43 -0.33 4.19e-10 Testicular germ cell tumor; LIHC cis rs637571 0.544 rs500161 chr11:65695438 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.4 0.41 1.24e-15 Eosinophil percentage of white cells; LIHC cis rs2204008 0.569 rs11495449 chr12:37995753 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 12.63 0.56 2.73e-30 Alzheimer's disease; LIHC cis rs17376456 0.825 rs28610997 chr5:93248374 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs56104184 0.775 rs17272700 chr19:49391770 G/A cg21252483 chr19:49399788 TULP2 -1.05 -11.95 -0.54 9.56e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs9768139 0.708 rs34267680 chr7:158115084 C/T cg25566285 chr7:158114605 PTPRN2 0.23 6.19 0.32 1.74e-9 Calcium levels; LIHC cis rs7312933 0.558 rs1051453 chr12:42852217 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.87 0.39 4.62e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs116095464 0.558 rs6882584 chr5:223411 A/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs9640161 0.830 rs13307276 chr7:150061525 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.29 -0.41 2.62e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs929354 0.742 rs2006844 chr7:157002851 G/A cg16102536 chr7:156981717 UBE3C 0.35 5.87 0.3 1.02e-8 Body mass index; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.64 0.38 2.21e-13 Prudent dietary pattern; LIHC cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg13395646 chr4:1353034 KIAA1530 -0.65 -9.37 -0.45 1.05e-18 Obesity-related traits; LIHC cis rs636291 0.517 rs673254 chr1:10550352 C/T cg17425144 chr1:10567563 PEX14 0.56 11.01 0.51 2.43e-24 Prostate cancer; LIHC cis rs9549328 0.800 rs9549616 chr13:113627762 T/G cg00071026 chr13:113650936 MCF2L -0.4 -6.04 -0.31 4e-9 Systolic blood pressure; LIHC cis rs5769707 0.521 rs5769720 chr22:50062133 G/C cg01652190 chr22:50026171 C22orf34 -0.29 -6.3 -0.32 9.2e-10 Monocyte count;Monocyte percentage of white cells; LIHC trans rs4566648 0.593 rs7683410 chr4:84183908 T/C cg06219686 chr17:29421884 NF1 -0.53 -6.11 -0.31 2.71e-9 Monocyte count; LIHC cis rs12579753 1.000 rs12579753 chr12:82219376 C/T cg07988820 chr12:82153109 PPFIA2 -0.48 -5.83 -0.3 1.27e-8 Resting heart rate; LIHC cis rs9399135 0.967 rs9402676 chr6:135355507 C/T cg22676075 chr6:135203613 NA 0.41 6.75 0.34 6.45e-11 Red blood cell count; LIHC cis rs9303401 0.614 rs56284918 chr17:57178838 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.45 0.56 1.34e-29 Cognitive test performance; LIHC cis rs700651 0.789 rs6715070 chr2:198898265 A/G cg00792783 chr2:198669748 PLCL1 -0.43 -6.28 -0.32 1.01e-9 Intracranial aneurysm; LIHC cis rs2273669 0.667 rs11757168 chr6:109301091 A/G cg05315195 chr6:109294784 ARMC2 -0.53 -5.88 -0.3 9.87e-9 Prostate cancer; LIHC cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.04 0.31 3.93e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17685 0.753 rs2108274 chr7:75781636 C/A cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7818688 0.697 rs35032356 chr8:95977484 G/T cg16049864 chr8:95962084 TP53INP1 0.62 6.74 0.34 6.69e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7572733 0.555 rs10202569 chr2:198934726 C/G cg10820045 chr2:198174542 NA 0.41 6.01 0.31 4.72e-9 Dermatomyositis; LIHC cis rs12765878 1.000 rs11191848 chr10:105650837 T/C cg11005552 chr10:105648138 OBFC1 0.39 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs875971 0.862 rs12698526 chr7:65969105 T/C cg11764359 chr7:65958608 NA 0.78 13.52 0.59 1.17e-33 Aortic root size; LIHC cis rs7216064 0.601 rs35453056 chr17:66039668 A/G cg12091567 chr17:66097778 LOC651250 0.86 14.74 0.62 2.01e-38 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs763014 0.932 rs2384972 chr16:674424 G/A cg27189623 chr16:705930 WDR90 0.42 6.91 0.35 2.43e-11 Height; LIHC cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg16405210 chr4:1374714 KIAA1530 -0.45 -5.75 -0.3 2.01e-8 Obesity-related traits; LIHC cis rs7909074 1.000 rs4481983 chr10:45400428 G/T cg04218760 chr10:45406644 TMEM72 -0.23 -7.37 -0.37 1.3e-12 Mean corpuscular volume; LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs6502050 0.871 rs8080366 chr17:80067298 A/G cg11859384 chr17:80120422 CCDC57 0.45 6.08 0.31 3.23e-9 Life satisfaction; LIHC cis rs7044106 0.791 rs10984994 chr9:123478769 A/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.7 -11.22 -0.52 4.45e-25 Hip circumference adjusted for BMI; LIHC cis rs2204008 0.540 rs3908193 chr12:38410907 G/T cg26384229 chr12:38710491 ALG10B -0.46 -6.03 -0.31 4.22e-9 Bladder cancer; LIHC cis rs11711311 1.000 rs9826808 chr3:113455644 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.05 -0.36 9.75e-12 IgG glycosylation; LIHC cis rs9457247 0.612 rs2237273 chr6:167443017 T/C cg12798992 chr6:167411361 FGFR1OP 0.45 6.94 0.35 2.01e-11 Crohn's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20033557 chr15:63414489 LACTB -0.59 -6.72 -0.34 7.56e-11 Systolic blood pressure; LIHC cis rs79057730 0.599 rs34411410 chr7:811721 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.8 8.9 0.43 3.33e-17 Initial pursuit acceleration; LIHC cis rs9303401 0.580 rs12603808 chr17:56578508 T/G cg25039879 chr17:56429692 SUPT4H1 0.81 9.04 0.44 1.2e-17 Cognitive test performance; LIHC cis rs1003719 0.715 rs1981432 chr21:38541356 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.87 -0.51 7.97e-24 Eye color traits; LIHC cis rs9926296 0.744 rs164749 chr16:89708224 A/C cg08949735 chr16:89699720 DPEP1 -0.41 -8.09 -0.4 1.06e-14 Vitiligo; LIHC cis rs7582720 1.000 rs72934732 chr2:203739856 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg10477989 chr11:68039601 C11orf24 -0.47 -6.82 -0.35 4.14e-11 Triglycerides; LIHC cis rs2760061 0.599 rs644794 chr1:228148670 T/C cg01200585 chr1:228362443 C1orf69 -0.4 -5.86 -0.3 1.08e-8 Diastolic blood pressure; LIHC cis rs8078723 1.000 rs8078723 chr17:38166879 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.56 -8.98 -0.44 1.85e-17 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6088590 0.965 rs6087619 chr20:33288511 C/G cg06115741 chr20:33292138 TP53INP2 0.6 8.64 0.42 2.26e-16 Coronary artery disease; LIHC cis rs12477438 0.501 rs6542868 chr2:99782848 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs17685 0.753 rs1639617 chr7:75701728 A/G cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10089 0.953 rs6595807 chr5:127531603 G/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.51 0.33 2.68e-10 Ileal carcinoids; LIHC cis rs7789940 0.904 rs56919252 chr7:75937520 T/C cg10167463 chr7:75959203 YWHAG -0.43 -6.75 -0.34 6.33e-11 Multiple sclerosis; LIHC cis rs797680 0.856 rs531358 chr1:93676011 C/T cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.65e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs4820539 0.966 rs5996470 chr22:23483255 G/A cg14186256 chr22:23484241 RTDR1 0.97 20.97 0.75 2.32e-63 Bone mineral density; LIHC cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg13047869 chr3:10149882 C3orf24 0.48 5.96 0.31 6.31e-9 Alzheimer's disease; LIHC cis rs796364 0.806 rs11694236 chr2:200916230 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23191292 chr6:157099924 ARID1B 0.42 6.4 0.33 5.03e-10 Cognitive function; LIHC cis rs3736594 0.513 rs62138968 chr2:27824485 C/G cg27432699 chr2:27873401 GPN1 0.46 6.92 0.35 2.29e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg18357526 chr6:26021779 HIST1H4A -0.59 -7.07 -0.36 8.73e-12 Blood metabolite levels; LIHC cis rs8180040 0.966 rs6792461 chr3:47473168 C/T cg16586182 chr3:47516702 SCAP 0.61 11.88 0.54 1.68e-27 Colorectal cancer; LIHC cis rs7412746 0.658 rs12068264 chr1:150727329 C/T cg17724175 chr1:150552817 MCL1 0.49 9.58 0.46 2.01e-19 Melanoma; LIHC cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 4.04e-13 Bipolar disorder; LIHC cis rs9902453 0.726 rs3110494 chr17:27976597 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.21 0.55 1.01e-28 Coffee consumption (cups per day); LIHC cis rs9911578 0.757 rs117987711 chr17:57111269 A/C cg05425664 chr17:57184151 TRIM37 0.55 7.8 0.39 7.78e-14 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.573 rs55661352 chr17:29045628 A/G cg14067834 chr17:29058358 SUZ12P 0.68 6.68 0.34 9.52e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs617791 0.669 rs4994056 chr11:65750997 G/A cg17712092 chr4:129076599 LARP1B 0.73 12.86 0.57 3.9e-31 Breast cancer; LIHC cis rs763121 0.853 rs9622833 chr22:39000397 G/A cg06022373 chr22:39101656 GTPBP1 0.69 11.97 0.54 8.25e-28 Menopause (age at onset); LIHC cis rs4803468 1.000 rs3810174 chr19:41904165 C/T cg09537434 chr19:41945824 ATP5SL -1.0 -20.81 -0.75 9.66e-63 Height; LIHC cis rs7772486 0.875 rs2748490 chr6:146329681 G/T cg13319975 chr6:146136371 FBXO30 -0.36 -6.03 -0.31 4.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9814567 1.000 rs2056604 chr3:134312648 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.45e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs5769707 0.632 rs135871 chr22:50008969 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.39 -0.41 1.3e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs4586057 0.514 rs12254390 chr10:92620148 G/C cg14313238 chr10:92632228 RPP30 0.36 5.99 0.31 5.4e-9 Economic and political preferences (time); LIHC cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg18404041 chr3:52824283 ITIH1 0.55 9.25 0.45 2.5e-18 Bipolar disorder; LIHC cis rs60871478 0.898 rs62432897 chr7:825429 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.52 6.17 0.32 1.95e-9 Cerebrospinal P-tau181p levels; LIHC cis rs600806 0.888 rs443345 chr1:109849254 A/G cg08911820 chr1:110026001 ATXN7L2 -0.56 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs6088580 0.524 rs6087616 chr20:33263033 T/C cg07148914 chr20:33460835 GGT7 -0.51 -7.15 -0.36 5.38e-12 Glomerular filtration rate (creatinine); LIHC cis rs12042938 0.507 rs1765777 chr1:231731742 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.58 -7.76 -0.39 9.66e-14 Neuranatomic and neurocognitive phenotypes; LIHC cis rs6701037 0.625 rs67332874 chr1:175128537 G/A cg00321850 chr1:175162397 KIAA0040 -0.43 -6.89 -0.35 2.77e-11 Alcohol dependence; LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg02782426 chr3:40428986 ENTPD3 0.34 6.29 0.32 9.76e-10 Renal cell carcinoma; LIHC cis rs7116495 0.737 rs670802 chr11:71799668 A/C cg26138937 chr11:71823887 C11orf51 -0.81 -7.98 -0.4 2.23e-14 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.24e-12 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.68 0.57 1.91e-30 Alzheimer's disease; LIHC cis rs6942756 1.000 rs7806089 chr7:128972215 C/G cg02491457 chr7:128862824 NA -0.62 -9.01 -0.44 1.48e-17 White matter hyperintensity burden; LIHC cis rs155076 1.000 rs58519241 chr13:21845006 C/A cg11317459 chr13:21872234 NA -1.17 -13.06 -0.58 6.87e-32 White matter hyperintensity burden; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg11965913 chr1:205819406 PM20D1 0.62 9.02 0.44 1.42e-17 Menarche (age at onset); LIHC cis rs9303280 0.901 rs9303277 chr17:37976469 C/T cg11212589 chr17:38028394 ZPBP2 0.33 6.65 0.34 1.18e-10 Self-reported allergy; LIHC cis rs11711311 1.000 rs7649590 chr3:113447267 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.45 -0.37 7.54e-13 IgG glycosylation; LIHC cis rs7072216 0.650 rs10883089 chr10:100163120 A/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.44 -0.33 4.04e-10 Metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22141780 chr2:132233726 TUBA3D 0.39 6.12 0.31 2.62e-9 Pancreatic cancer; LIHC cis rs1008375 0.932 rs6835077 chr4:17653285 A/T cg02297831 chr4:17616191 MED28 0.43 6.09 0.31 3.07e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1198430 0.929 rs1210852 chr1:23753533 T/C cg19827787 chr1:23763612 ASAP3 0.34 6.0 0.31 5.07e-9 Total cholesterol levels; LIHC cis rs6449957 0.832 rs12660017 chr5:67450350 T/C cg23036683 chr5:67512108 NA 0.43 6.06 0.31 3.68e-9 Cleft lip with or without cleft palate; LIHC cis rs172166 0.637 rs1225595 chr6:28151340 A/T cg16479474 chr6:28041457 NA 0.35 5.77 0.3 1.79e-8 Cardiac Troponin-T levels; LIHC cis rs6754311 0.509 rs12616520 chr2:136516748 A/T cg07169764 chr2:136633963 MCM6 -0.75 -10.71 -0.5 2.87e-23 Mosquito bite size; LIHC cis rs16854884 0.586 rs4616638 chr3:143735423 A/T cg06585982 chr3:143692056 C3orf58 -0.53 -6.92 -0.35 2.19e-11 Economic and political preferences (feminism/equality); LIHC cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg02951883 chr7:2050386 MAD1L1 -0.74 -12.72 -0.57 1.31e-30 Schizophrenia; LIHC cis rs637571 0.512 rs660118 chr11:65735174 G/C cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.82 0.3 1.38e-8 Eosinophil percentage of white cells; LIHC cis rs17401966 0.931 rs3748577 chr1:10357406 C/T cg19773385 chr1:10388646 KIF1B 0.4 7.07 0.36 8.71e-12 Hepatocellular carcinoma; LIHC cis rs4555082 0.830 rs2816614 chr14:105727359 C/T cg10792982 chr14:105748885 BRF1 0.45 6.03 0.31 4.22e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs425277 0.917 rs12410859 chr1:2038732 C/T cg24578937 chr1:2090814 PRKCZ 0.46 7.7 0.38 1.51e-13 Height; LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg14257396 chr1:107603778 NA 0.36 5.93 0.31 7.41e-9 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs801193 1.000 rs62466794 chr7:66191579 G/A cg26939375 chr7:64535504 NA 0.42 6.75 0.34 6.45e-11 Aortic root size; LIHC cis rs6973256 0.605 rs12707114 chr7:133345207 C/G cg10665199 chr7:133106180 EXOC4 0.34 5.83 0.3 1.26e-8 Intelligence (multi-trait analysis); LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg13903179 chr13:21900392 NA 0.37 6.39 0.33 5.29e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs3806843 0.735 rs3776129 chr5:140072292 G/A cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs6701037 1.000 rs11585617 chr1:175123186 C/G cg17845761 chr1:175162550 KIAA0040 -0.35 -5.8 -0.3 1.53e-8 Alcohol dependence; LIHC cis rs7312933 0.566 rs11181454 chr12:42746486 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.16 -0.4 6.41e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7551222 0.716 rs12041075 chr1:204492153 C/G cg20240347 chr1:204465584 NA -0.36 -7.54 -0.38 4.16e-13 Schizophrenia; LIHC cis rs11229555 0.645 rs11229489 chr11:58244917 A/G cg15696309 chr11:58395628 NA -0.62 -7.15 -0.36 5.27e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.53 -7.5 -0.38 5.53e-13 Lymphocyte counts; LIHC cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg03264133 chr6:25882463 NA -0.63 -8.85 -0.43 4.88e-17 Blood metabolite levels; LIHC cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.56 -8.61 -0.42 2.72e-16 Menarche (age at onset); LIHC trans rs2243480 1.000 rs57057549 chr7:65405738 A/G cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs4689592 0.523 rs6446565 chr4:7074027 A/G cg02503808 chr4:7069936 GRPEL1 0.79 11.71 0.54 7.15e-27 Monocyte percentage of white cells; LIHC cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg19539972 chr4:7069911 GRPEL1 0.67 9.68 0.46 9.29e-20 Monocyte percentage of white cells; LIHC cis rs7904368 0.659 rs3740169 chr10:16873547 C/T cg23933602 chr10:16859644 RSU1 0.52 7.91 0.39 3.48e-14 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs858239 0.600 rs6967419 chr7:23136310 C/T cg23682824 chr7:23144976 KLHL7 0.42 6.38 0.33 5.84e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs60871478 1.000 rs4397290 chr7:828493 T/C cg13844804 chr7:814759 HEATR2 -0.42 -5.73 -0.3 2.16e-8 Cerebrospinal P-tau181p levels; LIHC cis rs12701220 0.894 rs34712249 chr7:1036634 C/T cg00990874 chr7:1149470 C7orf50 -0.68 -9.5 -0.46 3.93e-19 Bronchopulmonary dysplasia; LIHC cis rs3736485 1.000 rs11631408 chr15:51746236 A/G cg08986416 chr15:51914746 DMXL2 -0.39 -5.78 -0.3 1.66e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs892961 0.932 rs2170863 chr17:75415037 C/T cg05865280 chr17:75406074 SEPT9 0.63 12.73 0.57 1.19e-30 Airflow obstruction; LIHC cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg20090690 chr10:134436459 INPP5A 0.45 6.07 0.31 3.45e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6696846 0.691 rs11240370 chr1:205118336 T/G cg21545522 chr1:205238299 TMCC2 0.32 6.14 0.32 2.29e-9 Red blood cell count; LIHC cis rs6988636 1.000 rs62521826 chr8:124186668 C/T cg15893493 chr8:124194847 FAM83A 0.89 8.3 0.41 2.48e-15 Urinary uromodulin levels; LIHC cis rs1055129 0.560 rs9891076 chr17:73911715 C/T cg19302996 chr17:73780495 UNK -0.47 -6.7 -0.34 8.5e-11 White matter hyperintensity burden; LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg08280861 chr8:58055591 NA 0.48 5.94 0.31 7.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs4478037 0.749 rs72856153 chr3:33111182 T/G cg16652328 chr3:33138982 GLB1;TMPPE -0.59 -7.93 -0.39 3.25e-14 Major depressive disorder; LIHC cis rs6599636 1 rs6599636 chr10:124677899 T/G cg05252487 chr10:124670562 FAM24A -0.32 -5.87 -0.3 1.03e-8 Red cell distribution width; LIHC cis rs10504073 0.584 rs56134839 chr8:49918899 C/T cg00325661 chr8:49890786 NA 0.39 9.29 0.45 1.81e-18 Blood metabolite ratios; LIHC cis rs5758511 0.680 rs58654759 chr22:42642576 T/C cg00645731 chr22:42541494 CYP2D7P1 0.53 8.58 0.42 3.38e-16 Birth weight; LIHC cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg17554472 chr22:41940697 POLR3H -0.54 -5.88 -0.3 9.92e-9 Vitiligo; LIHC cis rs754466 1.000 rs2278218 chr10:79680399 G/A cg17075019 chr10:79541650 NA -0.63 -8.51 -0.42 5.74e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3809566 0.963 rs4775608 chr15:63331940 A/G cg05771511 chr15:63340396 TPM1 0.47 7.04 0.36 1.05e-11 Platelet count; LIHC cis rs568617 1.000 rs687672 chr11:65649984 T/C cg04055107 chr11:65626734 MUS81;CFL1 -0.43 -6.18 -0.32 1.87e-9 Crohn's disease; LIHC cis rs7582720 1.000 rs72928608 chr2:203836507 G/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9611565 0.559 rs8139993 chr22:41995335 T/C cg06634786 chr22:41940651 POLR3H -0.56 -5.92 -0.3 7.82e-9 Vitiligo; LIHC cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg06481639 chr22:41940642 POLR3H 0.61 5.82 0.3 1.37e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg06618935 chr21:46677482 NA -0.3 -5.83 -0.3 1.3e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28735056 1.000 rs4798922 chr18:77628953 G/C cg20368463 chr18:77673604 PQLC1 -0.39 -6.84 -0.35 3.64e-11 Schizophrenia; LIHC cis rs2070488 0.775 rs6599207 chr3:38554901 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.7 -11.41 -0.53 9.22e-26 Electrocardiographic conduction measures; LIHC cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg18357526 chr6:26021779 HIST1H4A -0.54 -6.63 -0.34 1.3100000000000001e-10 Blood metabolite levels; LIHC cis rs950169 0.922 rs11631096 chr15:85100929 G/C cg17507749 chr15:85114479 UBE2QP1 0.75 8.74 0.43 1.06e-16 Schizophrenia; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs6665290 0.904 rs1045287 chr1:227178962 C/T cg10327440 chr1:227177885 CDC42BPA 1.15 26.51 0.82 6.09e-85 Myeloid white cell count; LIHC cis rs4478037 0.749 rs72856153 chr3:33111182 T/G cg27203090 chr3:33138513 GLB1;TMPPE -0.57 -7.49 -0.38 5.79e-13 Major depressive disorder; LIHC cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg16405210 chr4:1374714 KIAA1530 0.42 6.27 0.32 1.1e-9 Obesity-related traits; LIHC cis rs2153535 0.580 rs1119691 chr6:8460452 C/T cg21535247 chr6:8435926 SLC35B3 0.64 8.35 0.41 1.77e-15 Motion sickness; LIHC cis rs2075371 0.966 rs1901204 chr7:133985896 A/G cg11752832 chr7:134001865 SLC35B4 0.52 7.74 0.39 1.14e-13 Mean platelet volume; LIHC cis rs11673344 0.764 rs16971873 chr19:37469423 C/T cg27390819 chr19:37464633 NA -0.49 -5.92 -0.31 7.65e-9 Obesity-related traits; LIHC cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg25811766 chr13:21894605 NA 0.77 13.3 0.58 7.81e-33 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2361718 0.500 rs4889970 chr17:78096086 C/T cg09238746 chr17:78121135 EIF4A3 0.79 12.62 0.56 3.12e-30 Yeast infection; LIHC cis rs6570726 0.764 rs4263604 chr6:145916697 A/G cg13319975 chr6:146136371 FBXO30 -0.37 -5.8 -0.3 1.49e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs8038465 0.516 rs8037836 chr15:73859855 G/A cg15420318 chr15:73925796 NPTN 0.5 7.78 0.39 8.94e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7772486 0.806 rs2247317 chr6:146217570 C/T cg05347473 chr6:146136440 FBXO30 0.36 6.01 0.31 4.7e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17102423 1.000 rs4902364 chr14:65602006 G/A cg11161011 chr14:65562177 MAX -0.44 -6.02 -0.31 4.51e-9 Obesity-related traits; LIHC cis rs11893307 0.566 rs62179714 chr2:191567541 G/C cg10560079 chr2:191398806 TMEM194B -0.41 -5.75 -0.3 2e-8 Mean platelet volume; LIHC cis rs6835098 1.000 rs4695826 chr4:174089426 T/G cg08422745 chr4:174089978 GALNT7 -0.33 -5.86 -0.3 1.12e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs1775715 0.737 rs55859032 chr10:32213239 C/T cg14930904 chr10:32216787 ARHGAP12 0.36 6.47 0.33 3.39e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs1451375 0.617 rs10277662 chr7:50594836 C/T cg14593290 chr7:50529359 DDC 0.62 9.67 0.46 1.01e-19 Malaria; LIHC cis rs142472947 1 rs142472947 chr1:8520487 AAAG/A cg20416874 chr1:8611966 RERE 0.58 9.29 0.45 1.83e-18 White blood cell count; LIHC cis rs4808199 0.793 rs12459676 chr19:19425141 A/T cg03709012 chr19:19516395 GATAD2A 0.96 13.84 0.6 6.93e-35 Nonalcoholic fatty liver disease; LIHC cis rs7520050 0.966 rs11211241 chr1:46452683 T/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.43 6.35 0.32 6.93e-10 Red blood cell count;Reticulocyte count; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09380000 chr7:2650132 IQCE 0.35 6.45 0.33 3.89e-10 Longevity; LIHC cis rs3008870 1.000 rs1925411 chr1:67370292 C/T cg02640540 chr1:67518911 SLC35D1 0.44 6.02 0.31 4.59e-9 Lymphocyte percentage of white cells; LIHC cis rs1059312 0.808 rs12816551 chr12:129295616 T/C cg09035930 chr12:129282057 SLC15A4 0.6 11.2 0.52 5.04e-25 Systemic lupus erythematosus; LIHC cis rs9486719 1.000 rs2472889 chr6:96866803 T/G cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs7666738 0.830 rs11725652 chr4:98878362 G/A cg05340658 chr4:99064831 C4orf37 0.67 12.06 0.55 3.94e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs754466 0.580 rs11002301 chr10:79574078 G/A cg17075019 chr10:79541650 NA -0.8 -12.68 -0.57 1.78e-30 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg02891314 chr5:179741120 GFPT2 -0.42 -5.9 -0.3 8.69e-9 Height; LIHC cis rs2404602 0.692 rs2117369 chr15:76748861 A/T cg23625390 chr15:77176239 SCAPER 0.37 6.05 0.31 3.79e-9 Blood metabolite levels; LIHC cis rs5758511 0.679 rs55867855 chr22:42623258 G/A cg00645731 chr22:42541494 CYP2D7P1 0.54 8.63 0.42 2.42e-16 Birth weight; LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg27286337 chr10:134555280 INPP5A 0.89 14.26 0.61 1.59e-36 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg27572855 chr1:25598939 RHD 0.38 8.13 0.4 7.79e-15 Erythrocyte sedimentation rate; LIHC cis rs652260 0.663 rs580984 chr19:7881030 C/T cg26014689 chr19:7917955 EVI5L -0.66 -11.21 -0.52 4.64e-25 Menarche (age at onset); LIHC cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg00815214 chr21:47717953 NA -0.38 -5.95 -0.31 6.76e-9 Testicular germ cell tumor; LIHC cis rs9640161 0.659 rs7781827 chr7:150008858 T/C cg17279839 chr7:150038598 RARRES2 0.49 10.25 0.48 1.16e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs8141529 0.719 rs5762825 chr22:29223642 A/G cg02153584 chr22:29168773 CCDC117 0.58 9.27 0.45 2.11e-18 Lymphocyte counts; LIHC cis rs1005277 0.603 rs1998062 chr10:38457652 G/C cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.73 -0.3 2.16e-8 Extrinsic epigenetic age acceleration; LIHC cis rs2274273 0.773 rs8006525 chr14:55813394 T/G cg01864836 chr14:55583639 NA -0.4 -7.52 -0.38 4.98e-13 Protein biomarker; LIHC cis rs2625529 0.668 rs8192431 chr15:72492352 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.94 -0.31 6.97e-9 Red blood cell count; LIHC cis rs2439831 0.681 rs1549525 chr15:43627855 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.64 0.53 1.34e-26 Lung cancer in ever smokers; LIHC cis rs3815700 0.920 rs10426856 chr19:33096406 A/G cg02997394 chr19:33096574 ANKRD27 0.73 9.57 0.46 2.28e-19 Eosinophilic esophagitis; LIHC cis rs7945705 0.714 rs2653570 chr11:8987823 A/G cg12365402 chr11:9010492 NRIP3 -0.33 -8.76 -0.43 8.93e-17 Hemoglobin concentration; LIHC cis rs5758511 0.680 rs5758687 chr22:42656588 A/T cg00645731 chr22:42541494 CYP2D7P1 0.52 8.27 0.41 3.04e-15 Birth weight; LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg20607798 chr8:58055168 NA 0.62 7.92 0.39 3.38e-14 Developmental language disorder (linguistic errors); LIHC cis rs6942756 0.915 rs6946938 chr7:129004662 A/C cg02491457 chr7:128862824 NA -0.59 -8.9 -0.43 3.42e-17 White matter hyperintensity burden; LIHC cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs7914558 0.966 rs2297786 chr10:104679978 C/T cg15744005 chr10:104629667 AS3MT -0.4 -9.05 -0.44 1.08e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.12 -15.49 -0.64 2.23e-41 Gut microbiome composition (summer); LIHC cis rs9590974 0.663 rs1216860 chr13:47232268 C/T cg04092803 chr13:47240378 LRCH1 0.27 5.93 0.31 7.57e-9 PR segment; LIHC cis rs35110281 0.776 rs62226866 chr21:45024186 T/C cg01579765 chr21:45077557 HSF2BP -0.35 -6.56 -0.33 1.97e-10 Mean corpuscular volume; LIHC cis rs1816752 0.905 rs9511262 chr13:25012023 C/T cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.78e-10 Obesity-related traits; LIHC cis rs7572733 0.576 rs6734781 chr2:198759973 G/A cg03934865 chr2:198174659 NA 0.46 6.67 0.34 1.04e-10 Dermatomyositis; LIHC cis rs1707322 0.721 rs12045096 chr1:46114428 A/G cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.44 -0.33 3.94e-10 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.46 -6.6 -0.34 1.53e-10 Lymphocyte counts; LIHC cis rs892961 0.836 rs8071497 chr17:75414358 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.41 0.59 3.07e-33 Airflow obstruction; LIHC cis rs9291683 0.595 rs35250962 chr4:10048271 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.53 0.38 4.53e-13 Bone mineral density; LIHC trans rs1814175 0.509 rs60698301 chr11:49877672 G/A cg03929089 chr4:120376271 NA -0.83 -15.84 -0.65 8.89e-43 Height; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23854747 chr20:62612705 PRPF6 -0.54 -6.26 -0.32 1.15e-9 Systolic blood pressure; LIHC cis rs6088590 1.000 rs6087626 chr20:33347328 C/T cg06115741 chr20:33292138 TP53INP2 0.59 8.52 0.42 5.05e-16 Coronary artery disease; LIHC cis rs875971 1.000 rs4718344 chr7:65874381 C/A cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg14004847 chr7:1930337 MAD1L1 -0.49 -7.11 -0.36 6.66e-12 Schizophrenia; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg18306943 chr3:40428807 ENTPD3 -0.43 -7.57 -0.38 3.56e-13 Renal cell carcinoma; LIHC cis rs5770917 1.000 rs762676 chr22:51017794 A/G cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.49 -6.07 -0.31 3.34e-9 Narcolepsy; LIHC cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg04546413 chr19:29218101 NA 0.56 10.21 0.48 1.51e-21 Methadone dose in opioid dependence; LIHC cis rs9590974 0.705 rs1408224 chr13:47215218 G/A cg04092803 chr13:47240378 LRCH1 0.28 5.96 0.31 6.24e-9 PR segment; LIHC cis rs10197940 0.510 rs7602715 chr2:152421937 A/G cg19508488 chr2:152266495 RIF1 0.54 7.88 0.39 4.44e-14 Lung cancer; LIHC cis rs6121246 0.567 rs6060263 chr20:30193110 T/C cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs3859192 0.577 rs2227333 chr17:38174167 C/G cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.79 0.65 1.41e-42 White blood cell count; LIHC trans rs637571 0.522 rs3016868 chr11:65764383 C/T cg17712092 chr4:129076599 LARP1B 0.74 13.06 0.58 6.76e-32 Eosinophil percentage of white cells; LIHC cis rs8044995 0.636 rs9888986 chr16:68297228 G/A cg05110241 chr16:68378359 PRMT7 -0.63 -6.46 -0.33 3.57e-10 Schizophrenia; LIHC trans rs61931739 0.534 rs1387789 chr12:34056304 C/A cg26384229 chr12:38710491 ALG10B 0.47 6.64 0.34 1.2e-10 Morning vs. evening chronotype; LIHC cis rs1568889 1.000 rs9783281 chr11:28033786 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.95 0.35 1.88e-11 Bipolar disorder; LIHC cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg11764359 chr7:65958608 NA 0.59 6.29 0.32 9.54e-10 Diabetic kidney disease; LIHC trans rs2270221 0.812 rs11761300 chr7:31908052 G/C cg06873401 chr5:77792105 LHFPL2 0.5 6.13 0.31 2.4e-9 Endometriosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19988671 chr7:155589783 NA 0.42 6.38 0.33 5.82e-10 Pancreatic cancer; LIHC cis rs4268898 0.610 rs34216622 chr2:24463445 G/C cg06627628 chr2:24431161 ITSN2 -0.73 -9.76 -0.47 5.02e-20 Asthma; LIHC cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg04025307 chr7:1156635 C7orf50 0.57 9.31 0.45 1.64e-18 Longevity;Endometriosis; LIHC cis rs708547 0.624 rs1718886 chr4:57849251 C/T cg25525207 chr4:57843836 C4orf14;POLR2B -0.43 -6.75 -0.34 6.36e-11 Response to bleomycin (chromatid breaks); LIHC cis rs1577917 0.839 rs9450333 chr6:86519755 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.04 -0.31 4.03e-9 Response to antipsychotic treatment; LIHC cis rs7044106 0.708 rs991121 chr9:123370345 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.91 0.51 5.6e-24 Hip circumference adjusted for BMI; LIHC cis rs11098499 0.954 rs1480931 chr4:120395809 G/T cg09307838 chr4:120376055 NA 0.73 11.8 0.54 3.43e-27 Corneal astigmatism; LIHC cis rs1348850 0.526 rs2218575 chr2:178368997 C/A cg27490568 chr2:178487706 NA 1.0 11.23 0.52 3.93e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.95 -0.31 6.51e-9 Total body bone mineral density; LIHC cis rs2197308 0.692 rs1904964 chr12:37933241 T/A cg26384229 chr12:38710491 ALG10B 0.82 10.19 0.48 1.8e-21 Morning vs. evening chronotype; LIHC cis rs7131987 0.641 rs2015599 chr12:29435480 G/A cg14222432 chr12:29376421 FAR2 0.31 6.49 0.33 2.95e-10 QT interval; LIHC cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg07424592 chr7:64974309 NA -0.75 -8.71 -0.43 1.32e-16 Diabetic kidney disease; LIHC cis rs17776563 0.959 rs17197194 chr15:89111610 G/A cg05013243 chr15:89149849 MIR1179 0.46 7.61 0.38 2.62e-13 Thyroid hormone levels; LIHC cis rs2576037 0.526 rs2571026 chr18:44561795 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.47 6.76 0.34 5.88e-11 Personality dimensions; LIHC cis rs2479724 1.000 rs2479724 chr6:41890982 T/C cg17623882 chr6:41773611 USP49 -0.51 -7.74 -0.39 1.1e-13 Menarche (age at onset); LIHC cis rs8077889 1.000 rs2880329 chr17:41866168 T/A cg26893861 chr17:41843967 DUSP3 1.03 11.15 0.52 7.78e-25 Triglycerides; LIHC cis rs2067615 0.579 rs10746066 chr12:107129108 G/A cg15890332 chr12:107067104 RFX4 0.26 6.06 0.31 3.63e-9 Heart rate; LIHC cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.69 0.46 9.05e-20 Bipolar disorder; LIHC cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg14004847 chr7:1930337 MAD1L1 0.46 6.56 0.33 2.05e-10 Bipolar disorder and schizophrenia; LIHC cis rs1023500 0.505 rs134887 chr22:42674239 A/G cg00645731 chr22:42541494 CYP2D7P1 0.34 5.81 0.3 1.42e-8 Schizophrenia; LIHC cis rs11971779 0.553 rs10228643 chr7:139115420 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.29 0.49 8.39e-22 Diisocyanate-induced asthma; LIHC cis rs295137 0.836 rs1217456 chr2:201092279 C/T cg23649088 chr2:200775458 C2orf69 0.5 6.84 0.35 3.65e-11 Asthma (bronchodilator response); LIHC cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg11644478 chr21:40555479 PSMG1 -0.38 -5.85 -0.3 1.12e-8 Cognitive function; LIHC cis rs7937890 0.559 rs2575837 chr11:14498001 A/G cg02886208 chr11:14281011 SPON1 -0.44 -6.15 -0.32 2.17e-9 Mitochondrial DNA levels; LIHC cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg11502198 chr6:26597334 ABT1 0.57 8.66 0.42 1.9e-16 Intelligence (multi-trait analysis); LIHC cis rs992157 0.835 rs7559416 chr2:219150211 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.8 -12.7 -0.57 1.58e-30 Colorectal cancer; LIHC cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg07424592 chr7:64974309 NA -0.8 -9.31 -0.45 1.58e-18 Diabetic kidney disease; LIHC cis rs1577917 0.883 rs9450375 chr6:86756629 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.41 7.4 0.37 1.08e-12 Response to antipsychotic treatment; LIHC cis rs2235573 0.527 rs139862 chr22:38351986 T/C cg03989125 chr22:38214979 NA -0.44 -6.03 -0.31 4.34e-9 Glioblastoma;Glioma; LIHC cis rs2115630 0.905 rs1975277 chr15:85329558 C/T cg12501888 chr15:85177176 SCAND2 -0.48 -7.46 -0.37 7.07e-13 P wave terminal force; LIHC cis rs1443512 0.796 rs1822437 chr12:54340077 A/G cg25024717 chr12:54324583 NA 0.31 6.17 0.32 1.91e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs12086130 0.892 rs72904801 chr1:51442137 A/G cg07174182 chr1:51127561 FAF1 -0.76 -8.17 -0.4 6.13e-15 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs924607 0.510 rs1709542 chr5:662543 A/G cg24163568 chr5:669837 TPPP 0.29 5.94 0.31 7.02e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs67311347 0.955 rs4973999 chr3:40460383 G/A cg09455208 chr3:40491958 NA 0.32 6.53 0.33 2.33e-10 Renal cell carcinoma; LIHC cis rs7312933 0.558 rs11181466 chr12:42765181 A/T cg01256987 chr12:42539512 GXYLT1 -0.36 -5.91 -0.3 8.5e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6500602 0.647 rs4786514 chr16:4576798 A/C cg08645402 chr16:4508243 NA 0.39 7.24 0.36 3.03e-12 Schizophrenia; LIHC cis rs10508774 1.000 rs72793595 chr10:32737215 C/G cg01819863 chr10:32635814 EPC1 0.65 6.1 0.31 2.87e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1499280 1.000 rs1499280 chr5:52096889 C/A cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.76 -0.3 1.86e-8 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs1568889 1.000 rs12800354 chr11:28047723 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.63 0.34 1.34e-10 Bipolar disorder; LIHC cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg03517284 chr6:25882590 NA -0.64 -9.06 -0.44 9.93e-18 Blood metabolite levels; LIHC cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg03517284 chr6:25882590 NA 0.85 11.49 0.53 4.66e-26 Blood metabolite levels; LIHC cis rs2153535 0.580 rs6597334 chr6:8504779 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.42 0.41 1.07e-15 Motion sickness; LIHC cis rs826838 1.000 rs11610522 chr12:38687575 C/T cg26384229 chr12:38710491 ALG10B 1.07 14.89 0.63 5.24e-39 Heart rate; LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs344364 0.511 rs1742472 chr16:1953040 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.24 -0.36 2.92e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs6788895 1.000 rs7636866 chr3:150461568 A/T cg09723797 chr3:150481914 SIAH2 0.85 11.59 0.53 2e-26 Breast cancer; LIHC cis rs1278769 1.000 rs1278769 chr13:113536627 C/T cg00823993 chr13:113535758 ATP11A 0.5 6.73 0.34 7.05e-11 Interstitial lung disease; LIHC cis rs17102423 0.755 rs11158574 chr14:65579467 T/G cg11161011 chr14:65562177 MAX -0.57 -7.94 -0.39 2.99e-14 Obesity-related traits; LIHC cis rs10870270 0.500 rs9419217 chr10:133758379 A/G cg26149184 chr10:133730230 NA 0.38 5.84 0.3 1.24e-8 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6582630 0.593 rs12816835 chr12:38533304 C/T cg26384229 chr12:38710491 ALG10B -0.49 -6.79 -0.34 4.84e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs10744422 0.858 rs12426809 chr12:123327143 C/T cg07706471 chr12:123319906 HIP1R -0.57 -7.62 -0.38 2.57e-13 Schizophrenia; LIHC cis rs17685 0.712 rs2158867 chr7:75815141 C/A cg16684958 chr7:75615977 POR 0.48 8.12 0.4 8.54e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg20607798 chr8:58055168 NA 0.64 8.21 0.41 4.61e-15 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14103574 chr5:162932455 MAT2B 0.46 7.62 0.38 2.54e-13 Cognitive function; LIHC cis rs5769707 0.656 rs135875 chr22:50012419 T/G cg01652190 chr22:50026171 C22orf34 -0.34 -7.63 -0.38 2.35e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs12188164 0.543 rs2672722 chr5:453567 G/A cg08916839 chr5:415575 AHRR 0.29 6.27 0.32 1.08e-9 Cystic fibrosis severity; LIHC cis rs2607426 1.000 rs2607422 chr19:41276990 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.48 -5.8 -0.3 1.5e-8 Blood protein levels; LIHC cis rs9549367 0.789 rs9549715 chr13:113908240 G/C cg00898013 chr13:113819073 PROZ -0.42 -7.16 -0.36 5.08e-12 Platelet distribution width; LIHC cis rs34779708 0.966 rs17499811 chr10:35456215 G/A cg03585969 chr10:35415529 CREM 0.87 13.09 0.58 4.92e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs992157 0.735 rs13392177 chr2:219112956 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.8 -13.53 -0.59 1.1e-33 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15254786 chr2:207630414 MDH1B;FASTKD2 0.38 6.11 0.31 2.73e-9 Cognitive function; LIHC cis rs986417 0.901 rs8020867 chr14:61093246 A/T cg27398547 chr14:60952738 C14orf39 0.59 6.19 0.32 1.71e-9 Gut microbiota (bacterial taxa); LIHC cis rs16854884 0.558 rs6768153 chr3:143667429 C/A cg06585982 chr3:143692056 C3orf58 0.64 8.99 0.44 1.71e-17 Economic and political preferences (feminism/equality); LIHC cis rs7639513 0.767 rs9861472 chr3:12707776 A/T cg23032965 chr3:12705835 RAF1 -0.63 -7.73 -0.39 1.21e-13 Itch intensity from mosquito bite; LIHC trans rs9531686 1.000 rs9546999 chr13:85549012 G/C cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.31 6.24 0.32 1.26e-9 Anorexia nervosa; LIHC cis rs8017423 0.967 rs61989980 chr14:90727635 C/T cg04374321 chr14:90722782 PSMC1 0.78 15.15 0.63 4.85e-40 Mortality in heart failure; LIHC cis rs7131987 0.650 rs11050187 chr12:29472876 T/C cg00204748 chr12:29376779 FAR2 0.4 7.48 0.38 6.14e-13 QT interval; LIHC cis rs7618501 0.633 rs7628058 chr3:50039474 C/T cg21467203 chr3:49911342 NA -0.43 -7.59 -0.38 3.09e-13 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg11502198 chr6:26597334 ABT1 0.59 9.06 0.44 1e-17 Intelligence (multi-trait analysis); LIHC trans rs2243480 1.000 rs186378 chr7:65582058 A/C cg10756647 chr7:56101905 PSPH 1.07 13.4 0.59 3.25e-33 Diabetic kidney disease; LIHC cis rs7582720 1.000 rs72932561 chr2:203848402 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs748404 0.690 rs1079309 chr15:43783164 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.85 0.39 5.57e-14 Lung cancer; LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg06497051 chr1:156261200 TMEM79 0.37 5.9 0.3 8.83e-9 Tonsillectomy; LIHC cis rs6762477 0.748 rs3755831 chr3:50228767 G/T cg21467203 chr3:49911342 NA 0.36 6.23 0.32 1.37e-9 Menarche (age at onset); LIHC cis rs4631830 0.863 rs3101227 chr10:51520203 C/A cg20129853 chr10:51489980 NA -0.43 -9.29 -0.45 1.82e-18 Prostate-specific antigen levels; LIHC cis rs807029 0.544 rs55646950 chr10:102760996 C/T cg27255678 chr10:102756921 LZTS2 0.52 7.24 0.36 2.99e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs11971779 0.688 rs8137 chr7:139104461 A/C cg07862535 chr7:139043722 LUC7L2 -0.59 -10.38 -0.49 4.03e-22 Diisocyanate-induced asthma; LIHC cis rs4474465 1.000 rs10899517 chr11:78180507 A/T cg27205649 chr11:78285834 NARS2 -0.38 -5.84 -0.3 1.22e-8 Alzheimer's disease (survival time); LIHC cis rs9811920 0.570 rs1021102 chr3:99603780 T/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17808901 chr3:39093368 WDR48 0.42 6.36 0.33 6.44e-10 Cognitive function; LIHC cis rs1669338 0.588 rs3804783 chr3:3184442 C/T cg16797762 chr3:3221439 CRBN -0.94 -8.33 -0.41 2e-15 White matter integrity; LIHC cis rs1975974 0.872 rs17052344 chr17:21717543 A/G cg18423549 chr17:21743878 NA 0.44 5.72 0.3 2.37e-8 Psoriasis; LIHC cis rs3823572 0.542 rs2953636 chr7:133637904 A/G cg03336402 chr7:133662267 EXOC4 0.47 5.89 0.3 9.49e-9 Intelligence (multi-trait analysis); LIHC cis rs7845219 0.544 rs4735330 chr8:95917770 A/C cg13393036 chr8:95962371 TP53INP1 -0.31 -5.89 -0.3 9.33e-9 Type 2 diabetes; LIHC cis rs28830936 0.966 rs1918310 chr15:42065253 A/C cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.81 -0.3 1.4e-8 Diastolic blood pressure; LIHC cis rs9457247 0.508 rs9457268 chr6:167503639 A/T cg12798992 chr6:167411361 FGFR1OP 0.36 5.73 0.3 2.2e-8 Crohn's disease; LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs74181299 0.892 rs2540945 chr2:65289825 A/G cg05010058 chr2:65284262 CEP68 0.39 6.68 0.34 9.98e-11 Pulse pressure; LIHC cis rs3762637 0.943 rs3817040 chr3:122254769 G/A cg24169773 chr3:122142474 KPNA1 -0.45 -8.89 -0.43 3.7e-17 LDL cholesterol levels; LIHC cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.63e-18 Bipolar disorder; LIHC trans rs3780486 0.846 rs2209948 chr9:33138247 G/A cg04842962 chr6:43655489 MRPS18A 1.08 25.4 0.81 1.05e-80 IgG glycosylation; LIHC trans rs1814175 0.645 rs847639 chr11:49919603 C/T cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs11758351 0.929 rs6906367 chr6:26187125 C/T cg03854865 chr6:26224070 HIST1H3E 0.56 7.03 0.36 1.15e-11 Gout;Renal underexcretion gout; LIHC cis rs6977660 0.714 rs4719585 chr7:19823727 C/G cg07541023 chr7:19748670 TWISTNB 0.42 6.13 0.31 2.42e-9 Thyroid stimulating hormone; LIHC cis rs11690935 0.879 rs908671 chr2:172690265 C/G cg13550731 chr2:172543902 DYNC1I2 -0.92 -17.14 -0.68 5.47e-48 Schizophrenia; LIHC cis rs10911232 0.507 rs4652764 chr1:182994115 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.34 0.49 5.62e-22 Hypertriglyceridemia; LIHC cis rs2346177 0.605 rs7598712 chr2:46660452 G/T cg02822958 chr2:46747628 ATP6V1E2 0.32 5.83 0.3 1.27e-8 HDL cholesterol; LIHC cis rs15676 0.947 rs2997913 chr9:131589033 C/T cg13708974 chr9:131466143 PKN3 0.38 5.91 0.3 8.24e-9 Blood metabolite levels; LIHC trans rs7395662 0.517 rs10454483 chr11:48754997 A/G cg15704280 chr7:45808275 SEPT13 -0.49 -7.45 -0.37 7.47e-13 HDL cholesterol; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01056903 chr20:44601024 ZNF335 0.44 6.61 0.34 1.49e-10 Cognitive function; LIHC cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg21724239 chr8:58056113 NA 0.47 6.24 0.32 1.32e-9 Developmental language disorder (linguistic errors); LIHC cis rs295140 0.507 rs1369842 chr2:201108987 C/A cg23649088 chr2:200775458 C2orf69 -0.46 -6.33 -0.32 7.85e-10 QT interval; LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg26240231 chr7:1148101 C7orf50 -0.37 -5.71 -0.3 2.45e-8 Bronchopulmonary dysplasia; LIHC cis rs801193 0.569 rs2707847 chr7:66202871 C/G cg11764359 chr7:65958608 NA 0.75 12.68 0.57 1.77e-30 Aortic root size; LIHC cis rs3008870 1.000 rs4655663 chr1:67430103 C/T cg02640540 chr1:67518911 SLC35D1 0.46 6.27 0.32 1.11e-9 Lymphocyte percentage of white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13410877 chr18:55712976 NEDD4L 0.45 7.03 0.36 1.15e-11 Cognitive function; LIHC cis rs6430585 0.591 rs12475553 chr2:136483355 G/T cg07169764 chr2:136633963 MCM6 0.75 9.36 0.45 1.1e-18 Corneal structure; LIHC trans rs7178375 0.678 rs34678577 chr15:31177465 A/C cg04373760 chr16:53404718 NA 0.66 8.85 0.43 4.94e-17 Hypertriglyceridemia; LIHC cis rs4803468 0.905 rs284662 chr19:41932275 T/C cg09537434 chr19:41945824 ATP5SL -1.03 -21.52 -0.76 1.46e-65 Height; LIHC cis rs882732 1.000 rs5511 chr14:95033595 A/T cg14866387 chr14:95027382 SERPINA4 0.46 6.43 0.33 4.38e-10 Blood protein levels; LIHC cis rs854765 0.647 rs2974998 chr17:17995619 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.33 6.19 0.32 1.7e-9 Total body bone mineral density; LIHC cis rs11122272 0.735 rs2474634 chr1:231487017 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.94 -0.51 4.52e-24 Hemoglobin concentration; LIHC cis rs1593 0.641 rs28690003 chr4:187224562 G/A cg14349977 chr4:187219430 NA 0.47 6.74 0.34 6.73e-11 Activated partial thromboplastin time; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13686143 chr2:201828163 ORC2L 0.42 6.06 0.31 3.57e-9 Pancreatic cancer; LIHC cis rs875971 0.508 rs10242423 chr7:66059175 A/G cg14393609 chr7:65229607 NA -0.35 -5.75 -0.3 2.01e-8 Aortic root size; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs74181299 0.684 rs60136636 chr2:65338422 G/A cg05010058 chr2:65284262 CEP68 -0.4 -6.68 -0.34 9.55e-11 Pulse pressure; LIHC cis rs2857078 0.654 rs4793083 chr17:42312973 C/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.43 -7.68 -0.38 1.65e-13 Red cell distribution width;Reticulocyte count; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg21747090 chr2:27597821 SNX17 -0.39 -5.77 -0.3 1.79e-8 Total body bone mineral density; LIHC cis rs74417235 0.684 rs13185173 chr5:154055081 A/G cg25588787 chr5:154027256 NA 0.38 5.71 0.3 2.45e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs4319547 0.695 rs10846699 chr12:122853073 A/G cg23029597 chr12:123009494 RSRC2 0.51 7.33 0.37 1.73e-12 Body mass index; LIHC cis rs875971 1.000 rs2087647 chr7:65593188 C/A cg18876405 chr7:65276391 NA -0.39 -6.93 -0.35 2.08e-11 Aortic root size; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg20607798 chr8:58055168 NA 0.6 8.36 0.41 1.61e-15 Developmental language disorder (linguistic errors); LIHC cis rs2730245 0.505 rs2657360 chr7:158673604 A/G cg24397884 chr7:158709396 WDR60 0.42 6.25 0.32 1.23e-9 Height; LIHC cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg21724239 chr8:58056113 NA 0.63 7.33 0.37 1.62e-12 Developmental language disorder (linguistic errors); LIHC cis rs11822910 1.000 rs11820985 chr11:57200414 T/C cg00522883 chr11:57194120 SLC43A3 0.69 8.7 0.43 1.41e-16 Platelet distribution width; LIHC cis rs763121 0.853 rs4821816 chr22:39113134 G/A cg21395723 chr22:39101663 GTPBP1 0.38 6.17 0.32 1.91e-9 Menopause (age at onset); LIHC cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -8.97 -0.44 1.94e-17 Bipolar disorder; LIHC cis rs17253792 0.732 rs28380739 chr14:56088402 G/A cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg25038773 chr8:6638180 NA -0.3 -6.28 -0.32 1.04e-9 Monocyte count; LIHC cis rs12594515 1.000 rs11854554 chr15:45994546 C/G cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs11627756 0.915 rs12100848 chr14:103127449 T/C cg12046867 chr14:103022105 NA 0.39 5.92 0.3 7.82e-9 Mean platelet volume; LIHC cis rs6860806 0.507 rs273917 chr5:131659618 A/G cg24060327 chr5:131705240 SLC22A5 -0.82 -12.88 -0.57 3.09e-31 Breast cancer; LIHC cis rs7772486 0.790 rs2253307 chr6:146196181 T/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.94e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7223966 1.000 rs8075257 chr17:61728750 G/C cg05941027 chr17:61774174 LIMD2 0.29 5.75 0.3 1.98e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg10150615 chr22:24372951 LOC391322 -0.57 -8.28 -0.41 2.85e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs568617 1.000 rs568617 chr11:65653242 C/T cg04055107 chr11:65626734 MUS81;CFL1 0.44 6.44 0.33 4.17e-10 Crohn's disease; LIHC trans rs1945213 0.659 rs11227133 chr11:55836620 T/C cg15704280 chr7:45808275 SEPT13 0.59 7.58 0.38 3.25e-13 Acute lymphoblastic leukemia (childhood); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09060316 chr2:26467451 HADHB;HADHA -0.53 -6.76 -0.34 6.12e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg11890956 chr21:40555474 PSMG1 1.06 15.28 0.64 1.54e-40 Cognitive function; LIHC cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1008375 1.000 rs1558378 chr4:17650351 T/C cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2075371 0.863 rs12672691 chr7:133954431 C/T cg11752832 chr7:134001865 SLC35B4 0.47 5.96 0.31 6.44e-9 Mean platelet volume; LIHC cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6598955 0.724 rs12096059 chr1:26596709 G/A cg00852783 chr1:26633632 UBXN11 0.51 8.71 0.43 1.34e-16 Obesity-related traits; LIHC cis rs36051895 0.632 rs2149552 chr9:5132838 A/G cg02405213 chr9:5042618 JAK2 -0.67 -11.47 -0.53 5.58e-26 Pediatric autoimmune diseases; LIHC trans rs4290604 0.748 rs4663241 chr2:238085960 T/C cg15676719 chr1:167598521 RCSD1 -0.46 -6.21 -0.32 1.57e-9 Asthma; LIHC cis rs11792861 0.816 rs11788336 chr9:111688387 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 9.1 0.44 7.64e-18 Menarche (age at onset); LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs801193 0.761 rs2659888 chr7:66230171 T/G cg18876405 chr7:65276391 NA 0.42 7.35 0.37 1.52e-12 Aortic root size; LIHC cis rs1062177 0.724 rs2915828 chr5:151118121 G/A cg00977110 chr5:151150581 G3BP1 -0.56 -6.98 -0.35 1.58e-11 Preschool internalizing problems; LIHC trans rs7874142 0.616 rs10776902 chr9:137688048 C/T cg18109838 chr5:88185987 MEF2C 0.39 7.69 0.38 1.5700000000000001e-13 Longevity; LIHC cis rs3809566 0.963 rs12148057 chr15:63331509 A/T cg05771511 chr15:63340396 TPM1 0.47 7.04 0.36 1.05e-11 Platelet count; LIHC cis rs12594515 1.000 rs6493167 chr15:45986809 G/A cg06207120 chr15:45996521 NA 0.34 6.62 0.34 1.39e-10 Waist circumference;Weight; LIHC cis rs250677 0.687 rs1422581 chr5:148437386 C/T cg18129178 chr5:148520854 ABLIM3 0.47 7.24 0.36 3.08e-12 Breast cancer; LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg00091569 chr3:40428383 ENTPD3 0.4 6.83 0.35 4.01e-11 Renal cell carcinoma; LIHC cis rs11212737 0.765 rs2062116 chr11:108514951 C/T cg22776369 chr11:108536276 DDX10 0.38 6.33 0.32 7.65e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg27359949 chr3:14220525 XPC;LSM3 0.3 6.08 0.31 3.28e-9 Calcium levels; LIHC cis rs12477438 0.765 rs1115757 chr2:99660146 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg07438165 chr14:95942775 C14orf49 0.63 6.24 0.32 1.31e-9 Mild influenza (H1N1) infection; LIHC cis rs12291225 0.585 rs11023197 chr11:14380998 G/A cg19336497 chr11:14380999 RRAS2 -0.67 -14.13 -0.61 4.85e-36 Sense of smell; LIHC trans rs3783890 1.000 rs12889579 chr14:93789660 G/A cg02802420 chr16:69363236 PDF;COG8 0.32 6.32 0.32 8.12e-10 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16293631 chr17:38020606 IKZF3 -0.39 -6.06 -0.31 3.67e-9 Cognitive function; LIHC cis rs7219014 1 rs7219014 chr17:37624790 A/G cg07936489 chr17:37558343 FBXL20 -0.81 -12.96 -0.57 1.63e-31 Urinary metabolites; LIHC cis rs79839061 0.610 rs3775130 chr4:875144 G/A cg07828340 chr4:882639 GAK 0.85 7.15 0.36 5.38e-12 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.710 rs6851130 chr4:120133712 G/A cg25214090 chr10:38739885 LOC399744 -0.38 -6.26 -0.32 1.12e-9 Corneal astigmatism; LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg14893161 chr1:205819251 PM20D1 0.66 9.61 0.46 1.59e-19 Menarche (age at onset); LIHC cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs10504229 0.679 rs16921687 chr8:58053514 T/C cg20607798 chr8:58055168 NA 0.46 6.23 0.32 1.34e-9 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg18404041 chr3:52824283 ITIH1 -0.55 -8.9 -0.43 3.28e-17 Bipolar disorder; LIHC cis rs7091068 0.522 rs10748612 chr10:95494458 G/A cg20715218 chr10:95462985 C10orf4 0.58 6.41 0.33 4.75e-10 Urinary tract infection frequency; LIHC cis rs7116495 1.000 rs11235440 chr11:71826644 A/G cg26138937 chr11:71823887 C11orf51 0.84 8.54 0.42 4.41e-16 Severe influenza A (H1N1) infection; LIHC cis rs9486719 0.843 rs2103539 chr6:96844342 T/A cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg07061783 chr6:25882402 NA -0.47 -5.8 -0.3 1.49e-8 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs2073300 1.000 rs6048803 chr20:23438889 A/G cg12062639 chr20:23401060 NAPB 0.85 10.27 0.49 9.84e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs807029 0.533 rs3740487 chr10:102750783 C/A cg25179470 chr10:102756915 LZTS2 0.45 6.32 0.32 8.06e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg04632378 chr13:21900426 NA 0.38 6.49 0.33 2.94e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg04352962 chr1:209979756 IRF6 0.39 5.99 0.31 5.35e-9 Cleft lip with or without cleft palate; LIHC cis rs2242116 0.796 rs7623898 chr3:46974172 C/T cg27129171 chr3:47204927 SETD2 -0.56 -9.05 -0.44 1.09e-17 Birth weight; LIHC cis rs3741404 0.609 rs666497 chr11:63869821 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.67 10.83 0.51 1.04e-23 Platelet count; LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg12379764 chr21:47803548 PCNT -0.54 -7.76 -0.39 9.58e-14 Testicular germ cell tumor; LIHC cis rs7927771 0.524 rs10838782 chr11:47877800 A/G cg20307385 chr11:47447363 PSMC3 0.71 10.58 0.5 7.85e-23 Subjective well-being; LIHC cis rs7258465 0.931 rs1560119 chr19:18573675 A/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.43 -0.37 8.68e-13 Breast cancer; LIHC cis rs11229555 0.645 rs61903159 chr11:58184475 G/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs921968 0.643 rs62191565 chr2:219482017 C/T cg17980119 chr2:219472607 PLCD4 0.33 5.72 0.3 2.31e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg12311346 chr5:56204834 C5orf35 -0.58 -7.58 -0.38 3.34e-13 Initial pursuit acceleration; LIHC cis rs593982 0.925 rs585272 chr11:65505289 A/G cg08755490 chr11:65554678 OVOL1 0.55 8.56 0.42 3.82e-16 Atopic dermatitis; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg22082706 chr11:70001938 ANO1 0.44 6.53 0.33 2.41e-10 Bilirubin levels; LIHC cis rs7937682 0.855 rs10891285 chr11:111527775 T/C cg09085632 chr11:111637200 PPP2R1B -1.06 -13.58 -0.59 6.77e-34 Primary sclerosing cholangitis; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg20887711 chr4:1340912 KIAA1530 0.81 12.72 0.57 1.25e-30 Longevity; LIHC trans rs12478296 0.892 rs11897561 chr2:243014976 C/A cg01596870 chr19:55963115 NA -0.66 -9.36 -0.45 1.1e-18 Obesity-related traits; LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg00280220 chr17:61926910 NA 0.42 6.79 0.34 4.88e-11 Prudent dietary pattern; LIHC cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg09904177 chr6:26538194 HMGN4 0.57 11.34 0.52 1.58e-25 Intelligence (multi-trait analysis); LIHC cis rs539514 0.550 rs2328956 chr13:76294595 G/A cg04757411 chr13:76259545 LMO7 -0.46 -8.22 -0.41 4.39e-15 Type 1 diabetes; LIHC cis rs12474201 0.775 rs7584870 chr2:46973400 A/T cg06386533 chr2:46925753 SOCS5 0.63 7.55 0.38 3.93e-13 Height; LIHC cis rs10791323 0.569 rs2282602 chr11:133714522 G/A cg06766960 chr11:133703094 NA -0.66 -11.13 -0.52 8.89e-25 Childhood ear infection; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26755097 chr6:30711844 FLOT1;IER3 0.45 6.45 0.33 3.78e-10 Hepatitis; LIHC cis rs1707322 0.691 rs11211174 chr1:46220816 C/G cg03146154 chr1:46216737 IPP 0.6 10.28 0.49 9.16e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1728785 0.901 rs11075688 chr16:68655924 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.48 -6.1 -0.31 2.89e-9 Ulcerative colitis; LIHC cis rs57221529 0.766 rs56278696 chr5:582669 A/G cg09021430 chr5:549028 NA -0.44 -8.65 -0.42 1.97e-16 Lung disease severity in cystic fibrosis; LIHC cis rs4706831 0.647 rs627240 chr6:80985885 C/A cg08355045 chr6:80787529 NA -0.29 -5.78 -0.3 1.66e-8 Joint mobility (Beighton score); LIHC cis rs4423214 1.000 rs28364617 chr11:71159764 T/G cg24826892 chr11:71159390 DHCR7 0.56 7.13 0.36 5.91e-12 Vitamin D levels; LIHC cis rs1023500 0.551 rs61665536 chr22:42512613 A/G cg04733989 chr22:42467013 NAGA -0.64 -9.18 -0.44 4.09e-18 Schizophrenia; LIHC cis rs7727544 0.684 rs274567 chr5:131714409 C/T cg24060327 chr5:131705240 SLC22A5 0.61 8.87 0.43 4.26e-17 Blood metabolite levels; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.11 -0.31 2.69e-9 Total body bone mineral density; LIHC cis rs11676348 0.808 rs4674267 chr2:219046437 C/T cg00012203 chr2:219082015 ARPC2 -0.48 -6.33 -0.32 7.49e-10 Ulcerative colitis; LIHC cis rs7100689 0.622 rs1890890 chr10:82090643 A/T cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs739401 0.611 rs391188 chr11:3047634 G/A cg20651018 chr11:3035856 CARS -0.35 -5.8 -0.3 1.51e-8 Longevity; LIHC cis rs2839186 0.721 rs13051200 chr21:47701693 A/T cg12379764 chr21:47803548 PCNT -0.6 -8.77 -0.43 8.27e-17 Testicular germ cell tumor; LIHC trans rs1005277 0.579 rs2472175 chr10:38382901 T/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs17685 0.753 rs10245584 chr7:75745866 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9818758 0.607 rs35060561 chr3:49255503 T/C cg06212747 chr3:49208901 KLHDC8B -0.67 -5.87 -0.3 1.03e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs12478296 0.901 rs7420176 chr2:243005277 G/A cg06360820 chr2:242988706 NA -0.81 -12.21 -0.55 1.02e-28 Obesity-related traits; LIHC cis rs1707322 1.000 rs12133129 chr1:46373348 C/T cg03146154 chr1:46216737 IPP 0.47 7.66 0.38 1.88e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg03806693 chr22:41940476 POLR3H -1.09 -12.3 -0.55 4.71e-29 Vitiligo; LIHC trans rs804280 0.662 rs11250164 chr8:11610686 C/T cg25038773 chr8:6638180 NA 0.32 6.84 0.35 3.55e-11 Myopia (pathological); LIHC cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs3885839 chr7:65290403 G/T cg18252515 chr7:66147081 NA -1.3 -16.6 -0.67 8.39e-46 Diabetic kidney disease; LIHC cis rs8180040 0.726 rs4234465 chr3:47026885 C/G cg16586182 chr3:47516702 SCAP -0.47 -8.45 -0.42 8.76e-16 Colorectal cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10175688 chr17:6544015 TXNDC17;KIAA0753 -0.52 -6.58 -0.34 1.74e-10 Systolic blood pressure; LIHC cis rs17376456 0.569 rs7736892 chr5:93205597 G/A cg25358565 chr5:93447407 FAM172A -0.8 -7.7 -0.38 1.47e-13 Diabetic retinopathy; LIHC cis rs4684776 0.935 rs6772675 chr3:11376080 C/G cg00170343 chr3:11313890 ATG7 -0.51 -6.83 -0.35 3.93e-11 Small vessel stroke; LIHC cis rs9419702 0.614 rs9419567 chr10:133535149 C/G cg04492858 chr10:133558786 NA 0.44 6.56 0.33 1.97e-10 Survival in rectal cancer; LIHC cis rs56235845 0.694 rs4532376 chr5:176774403 G/A cg17509989 chr5:176798049 RGS14 0.63 8.43 0.41 9.770000000000001e-16 Hemoglobin concentration;Hematocrit; LIHC cis rs838721 0.574 rs34332006 chr2:234257452 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.41 5.83 0.3 1.25e-8 Total body bone mineral density; LIHC cis rs2270431 1 rs2270431 chr14:75270635 T/C cg11812906 chr14:75593930 NEK9 0.38 5.88 0.3 9.97e-9 Neuroticism; LIHC cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg04546413 chr19:29218101 NA 0.55 10.23 0.48 1.31e-21 Methadone dose in opioid dependence; LIHC cis rs965469 0.625 rs1043159 chr20:3232031 C/T cg25506879 chr20:3388711 C20orf194 -0.52 -7.22 -0.36 3.41e-12 IFN-related cytopenia; LIHC cis rs3020736 0.500 rs1801311 chr22:42486723 G/A cg04733989 chr22:42467013 NAGA -0.66 -9.45 -0.45 5.64e-19 Autism spectrum disorder or schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00930347 chr6:110012366 AKD1;FIG4 0.48 6.4 0.33 5.18e-10 Pancreatic cancer; LIHC cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg06108461 chr20:60628389 TAF4 -1.03 -18.01 -0.7 1.74e-51 Body mass index; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg16132339 chr22:24313637 DDTL;DDT 0.63 11.23 0.52 4.05e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7659604 0.540 rs13113421 chr4:122670064 G/A cg19671926 chr4:122722719 EXOSC9 0.48 6.97 0.35 1.69e-11 Type 2 diabetes; LIHC cis rs1144333 0.655 rs1417402 chr1:76437196 C/T cg10523679 chr1:76189770 ACADM 0.46 6.05 0.31 3.77e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs11098499 0.775 rs67281037 chr4:120281157 G/C cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs10857712 0.950 rs7906765 chr10:135225460 G/T cg19623624 chr10:135278901 LOC619207 -0.44 -6.86 -0.35 3.31e-11 Systemic lupus erythematosus; LIHC cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg12379764 chr21:47803548 PCNT -0.58 -8.22 -0.41 4.19e-15 Testicular germ cell tumor; LIHC cis rs2404602 0.569 rs2469249 chr15:76772062 C/T cg23625390 chr15:77176239 SCAPER -0.46 -7.53 -0.38 4.65e-13 Blood metabolite levels; LIHC cis rs6430585 0.583 rs4594504 chr2:136625113 A/C cg07169764 chr2:136633963 MCM6 1.34 23.21 0.78 3.04e-72 Corneal structure; LIHC cis rs11122272 0.735 rs2749716 chr1:231486908 T/C cg06096015 chr1:231504339 EGLN1 0.5 9.2 0.45 3.56e-18 Hemoglobin concentration; LIHC cis rs4638749 0.603 rs34153365 chr2:108846583 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs7847628 0.550 rs12343516 chr9:123603469 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.73 12.33 0.55 3.91e-29 Birth weight; LIHC cis rs16854884 0.739 rs1075113 chr3:143760535 C/T cg06585982 chr3:143692056 C3orf58 0.45 6.34 0.32 7.4e-10 Economic and political preferences (feminism/equality); LIHC cis rs6912958 0.781 rs2325064 chr6:88224467 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.09 -0.4 1.05e-14 Monocyte percentage of white cells; LIHC trans rs2727020 0.523 rs4115783 chr11:49556026 G/A cg15704280 chr7:45808275 SEPT13 0.78 11.77 0.54 4.55e-27 Coronary artery disease; LIHC cis rs10792665 0.512 rs10792660 chr11:82597704 C/G cg24227371 chr11:82718527 RAB30 0.27 6.39 0.33 5.53e-10 Obesity-related traits; LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg06873352 chr17:61820015 STRADA 0.52 7.68 0.38 1.64e-13 Height; LIHC cis rs919433 0.750 rs788012 chr2:198229856 A/T cg03934865 chr2:198174659 NA 0.54 8.19 0.41 5.11e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10540 1.000 rs12801148 chr11:511707 T/G cg03576123 chr11:487126 PTDSS2 -1.03 -7.25 -0.36 2.89e-12 Body mass index; LIHC cis rs35892873 0.920 rs9865702 chr3:126092351 A/G cg15490784 chr3:126061950 KLF15 0.45 6.72 0.34 7.6e-11 Male-pattern baldness; LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg02782426 chr3:40428986 ENTPD3 -0.32 -6.06 -0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs7089973 0.604 rs2420067 chr10:116590348 A/G cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.24 -0.32 1.32e-9 Total body bone mineral density; LIHC cis rs9649213 0.614 rs3944111 chr7:98005766 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.56 -9.92 -0.47 1.51e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs7945705 0.837 rs10769966 chr11:8847041 C/A cg12365402 chr11:9010492 NRIP3 0.24 5.84 0.3 1.19e-8 Hemoglobin concentration; LIHC cis rs9911578 1.000 rs3744109 chr17:56594197 C/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.64 -0.69 5.52e-50 Intelligence (multi-trait analysis); LIHC cis rs12971120 0.891 rs12968731 chr18:72169708 G/T cg26446133 chr18:72167187 CNDP2 -0.81 -15.07 -0.63 9.98e-40 Refractive error; LIHC cis rs595982 0.527 rs55670257 chr19:49382654 G/A cg15549821 chr19:49342101 PLEKHA4 -0.65 -5.92 -0.3 7.83e-9 Red cell distribution width; LIHC trans rs2727020 0.658 rs10839269 chr11:49385596 A/G cg18944383 chr4:111397179 ENPEP 0.26 6.37 0.33 6.02e-10 Coronary artery disease; LIHC cis rs12908161 0.959 rs62019472 chr15:85331493 A/G cg12863693 chr15:85201151 NMB 0.45 6.33 0.32 7.53e-10 Schizophrenia; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg20284773 chr1:156736924 PRCC -0.38 -6.15 -0.32 2.1e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2257205 0.667 rs7211439 chr17:56847832 A/T cg05425664 chr17:57184151 TRIM37 -0.6 -6.61 -0.34 1.5e-10 Pancreatic cancer; LIHC cis rs67311347 1.000 rs2168111 chr3:40395325 T/G cg13409248 chr3:40428643 ENTPD3 0.4 6.64 0.34 1.2e-10 Renal cell carcinoma; LIHC cis rs74233809 0.901 rs3824754 chr10:104614350 C/T cg03493300 chr10:104813866 CNNM2 0.42 5.82 0.3 1.38e-8 Birth weight; LIHC cis rs600806 0.778 rs4970761 chr1:109995398 C/T cg23091122 chr1:110024289 SYPL2 -0.52 -6.93 -0.35 2.04e-11 Intelligence (multi-trait analysis); LIHC cis rs116095464 0.850 rs10055295 chr5:243749 G/A cg22496380 chr5:211416 CCDC127 -1.03 -10.7 -0.5 3.15e-23 Breast cancer; LIHC cis rs637571 0.584 rs7107912 chr11:65603252 G/A cg26695010 chr11:65641043 EFEMP2 0.55 7.86 0.39 4.94e-14 Eosinophil percentage of white cells; LIHC trans rs916888 0.773 rs199457 chr17:44795469 C/T cg12297030 chr17:43662878 NA -0.63 -6.09 -0.31 3.08e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2242116 0.900 rs1001284 chr3:46933960 C/G cg27129171 chr3:47204927 SETD2 0.48 7.57 0.38 3.52e-13 Birth weight; LIHC cis rs13108904 0.901 rs1316393 chr4:1315619 A/G cg19318889 chr4:1322082 MAEA -0.48 -6.63 -0.34 1.3100000000000001e-10 Obesity-related traits; LIHC trans rs79976124 0.837 rs74327235 chr6:66648353 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.77 0.34 5.54e-11 Type 2 diabetes; LIHC cis rs10174077 0.874 rs10186656 chr2:152475938 T/G cg19508488 chr2:152266495 RIF1 0.5 7.05 0.36 9.83e-12 Squamous cell lung carcinoma; LIHC cis rs8114671 0.562 rs1060615 chr20:33478381 C/T cg07148914 chr20:33460835 GGT7 -0.62 -9.65 -0.46 1.16e-19 Height; LIHC trans rs1005277 0.505 rs1208689 chr10:38097775 C/G cg27523141 chr10:43048294 ZNF37B 0.39 6.89 0.35 2.77e-11 Extrinsic epigenetic age acceleration; LIHC cis rs908922 0.651 rs11205035 chr1:152532832 A/G cg20991723 chr1:152506922 NA 0.59 10.28 0.49 8.92e-22 Hair morphology; LIHC trans rs4650994 1.000 rs17276527 chr1:178520680 G/A cg05059571 chr16:84539110 KIAA1609 -0.38 -6.36 -0.33 6.41e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs796364 0.951 rs971232 chr2:200792881 C/T cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.61e-9 Schizophrenia; LIHC cis rs11992186 0.505 rs7845203 chr8:8145440 A/G cg06636001 chr8:8085503 FLJ10661 0.46 6.24 0.32 1.27e-9 Neuroticism; LIHC cis rs13108904 0.901 rs66987549 chr4:1272617 C/T cg00684032 chr4:1343700 KIAA1530 0.39 6.27 0.32 1.12e-9 Obesity-related traits; LIHC cis rs7927771 0.965 rs12364432 chr11:47902883 G/A cg20135002 chr11:47629003 NA -0.51 -8.59 -0.42 3.23e-16 Subjective well-being; LIHC cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg00166722 chr3:10149974 C3orf24 0.51 5.92 0.3 7.85e-9 Alzheimer's disease; LIHC cis rs7116495 0.867 rs597513 chr11:71797422 T/A cg26138937 chr11:71823887 C11orf51 -0.68 -6.85 -0.35 3.36e-11 Severe influenza A (H1N1) infection; LIHC cis rs870825 0.616 rs28636679 chr4:185627481 C/T cg04058563 chr4:185651563 MLF1IP 0.77 7.67 0.38 1.81e-13 Blood protein levels; LIHC cis rs4950322 0.576 rs4950427 chr1:146862903 T/C cg25205988 chr1:146714368 CHD1L 0.42 5.92 0.3 7.97e-9 Protein quantitative trait loci; LIHC cis rs1707322 0.717 rs2991988 chr1:46082431 C/A cg24296786 chr1:45957014 TESK2 0.4 5.71 0.3 2.44e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2209875 1.000 rs10867159 chr9:91800566 A/G cg26057616 chr1:222234397 NA 0.38 6.32 0.32 8.33e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs829880 0.570 rs4488248 chr12:98853688 G/C cg25150519 chr12:98850993 NA 0.58 8.47 0.42 7.29e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs2952156 0.959 rs1565922 chr17:37831035 A/G cg00129232 chr17:37814104 STARD3 -0.5 -9.29 -0.45 1.8e-18 Asthma; LIHC cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs3781684 1.000 rs7122312 chr11:76812827 C/G cg19164997 chr11:76818702 CAPN5 0.48 6.59 0.34 1.64e-10 Cognitive performance; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12187049 chr5:70882888 MCCC2 0.48 7.45 0.37 7.55e-13 Cognitive function; LIHC cis rs2836974 0.644 rs4818017 chr21:40690561 G/T cg17971929 chr21:40555470 PSMG1 -0.45 -6.95 -0.35 1.86e-11 Cognitive function; LIHC cis rs6450176 0.909 rs2448 chr5:53302354 T/C ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.6 -0.62 7.2e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg05552183 chr6:42928497 GNMT 0.86 13.41 0.59 2.92e-33 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg11060661 chr22:24314208 DDT;DDTL 0.63 10.54 0.5 1.1e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.89 8.54 0.42 4.52e-16 Platelet count; LIHC cis rs1707322 0.721 rs10890333 chr1:46100322 T/C cg03146154 chr1:46216737 IPP 0.57 9.86 0.47 2.36e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs916888 0.610 rs199444 chr17:44818276 T/C cg22968622 chr17:43663579 NA 0.49 7.17 0.36 4.77e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs67311347 0.822 rs9826847 chr3:40345312 A/T cg13409248 chr3:40428643 ENTPD3 0.38 5.84 0.3 1.23e-8 Renal cell carcinoma; LIHC cis rs13217239 0.574 rs9366680 chr6:27006123 A/T cg18867708 chr6:26865862 GUSBL1 0.51 7.86 0.39 4.95e-14 Schizophrenia; LIHC cis rs4699052 1.000 rs4699052 chr4:104137790 C/T cg16532752 chr4:104119610 CENPE -0.41 -6.65 -0.34 1.18e-10 Testicular germ cell tumor; LIHC trans rs7618501 1.000 rs11130219 chr3:49752427 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs2346177 0.605 rs7556828 chr2:46663172 A/G cg02822958 chr2:46747628 ATP6V1E2 -0.31 -5.78 -0.3 1.68e-8 HDL cholesterol; LIHC cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg27170947 chr2:26402098 FAM59B 0.67 8.32 0.41 2.18e-15 Gut microbiome composition (summer); LIHC cis rs3806843 0.966 rs2563263 chr5:140137644 A/G cg16179182 chr5:140090404 VTRNA1-1 -0.36 -6.09 -0.31 3.02e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs654384 0.898 rs1077472 chr7:4175323 G/A cg26675336 chr15:86133334 AKAP13 0.3 6.16 0.32 2.08e-9 Positive affect; LIHC cis rs9649213 0.593 rs7787858 chr7:98009914 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.85 -0.3 1.15e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs854765 0.647 rs712267 chr17:18021607 G/A cg04398451 chr17:18023971 MYO15A -0.78 -13.63 -0.59 4.37e-34 Total body bone mineral density; LIHC cis rs9379945 1 rs9379945 chr6:26907831 T/C cg12826209 chr6:26865740 GUSBL1 0.76 7.5 0.38 5.53e-13 Intelligence (multi-trait analysis); LIHC cis rs1509123 0.609 rs7224971 chr17:6713999 A/T cg12642237 chr17:6703447 TEKT1 0.89 7.63 0.38 2.38e-13 Blood metabolite levels; LIHC cis rs9911578 0.935 rs304261 chr17:56813782 A/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.63 -0.42 2.42e-16 Intelligence (multi-trait analysis); LIHC cis rs1434579 0.865 rs35813988 chr19:44940420 G/A cg15540054 chr19:45004280 ZNF180 0.57 7.95 0.39 2.8e-14 Tuberculosis; LIHC trans rs1945213 0.694 rs10895985 chr11:55831595 T/C cg03929089 chr4:120376271 NA 0.53 6.85 0.35 3.39e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs709400 0.663 rs2273703 chr14:103918029 C/G cg26031613 chr14:104095156 KLC1 0.71 9.53 0.46 3e-19 Body mass index; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg22164250 chr7:139256604 HIPK2 0.51 6.18 0.32 1.85e-9 Lung function (FEV1); LIHC cis rs9549328 0.800 rs9549619 chr13:113632620 C/G cg00071026 chr13:113650936 MCF2L -0.37 -5.82 -0.3 1.36e-8 Systolic blood pressure; LIHC cis rs1552244 0.816 rs13059144 chr3:10010197 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs2180341 0.782 rs6924274 chr6:127721556 T/A cg24812749 chr6:127587940 RNF146 0.8 12.5 0.56 9.03e-30 Breast cancer; LIHC cis rs151997 1.000 rs72758246 chr5:50246783 G/C cg06027927 chr5:50259733 NA 0.6 7.96 0.4 2.56e-14 Callous-unemotional behaviour; LIHC cis rs8177179 0.967 rs6439436 chr3:133453779 C/T cg16262614 chr3:133464971 TF -0.45 -10.37 -0.49 4.36e-22 Iron status biomarkers (transferrin levels); LIHC cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.67 0.42 1.73e-16 Platelet count; LIHC cis rs12702595 0.818 rs7787942 chr7:7270012 A/T cg04827551 chr7:7268805 C1GALT1 0.37 6.7 0.34 8.49e-11 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg11905131 chr22:24372483 LOC391322 0.61 8.58 0.42 3.44e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8062405 1.000 rs62037365 chr16:28868962 C/G cg16576597 chr16:28551801 NUPR1 0.38 6.21 0.32 1.57e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs918629 0.567 rs1458018 chr5:95253295 G/T cg10483112 chr5:95245456 ELL2 -0.38 -7.17 -0.36 4.8e-12 IgG glycosylation; LIHC cis rs7223966 1.000 rs11654335 chr17:61797579 A/T cg05941027 chr17:61774174 LIMD2 0.36 7.54 0.38 4.22e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3736485 0.932 rs2278989 chr15:51914716 T/C cg08986416 chr15:51914746 DMXL2 -0.47 -7.01 -0.35 1.28e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs7618501 0.966 rs2352974 chr3:49890613 C/T cg21659725 chr3:3221576 CRBN 0.94 17.6 0.69 7.91e-50 Intelligence (multi-trait analysis); LIHC cis rs868036 0.718 rs3784710 chr15:68072458 T/C cg24579218 chr15:68104479 NA -0.34 -5.81 -0.3 1.42e-8 Restless legs syndrome; LIHC cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.57 9.5 0.46 3.68e-19 Bipolar disorder; LIHC cis rs694739 0.734 rs663743 chr11:64107735 G/A cg02228329 chr11:64053129 BAD;GPR137 0.71 10.26 0.49 1e-21 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs6138458 1.000 rs6707 chr20:24944166 C/T cg26195577 chr20:24973756 C20orf3 1.17 15.19 0.63 3.36e-40 Blood protein levels; LIHC cis rs7412746 0.658 rs7521719 chr1:150913134 G/A cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs62034325 0.697 rs710410 chr16:28603342 A/G cg00204512 chr16:28754710 NA 0.42 7.09 0.36 7.97e-12 Body mass index; LIHC trans rs11098499 0.863 rs6534139 chr4:120449456 A/G cg25214090 chr10:38739885 LOC399744 -0.62 -9.95 -0.47 1.17e-20 Corneal astigmatism; LIHC cis rs4713118 0.869 rs9283883 chr6:27715470 T/A cg20933634 chr6:27740509 NA 0.47 6.19 0.32 1.69e-9 Parkinson's disease; LIHC cis rs950169 0.580 rs11634322 chr15:85172209 C/T cg17507749 chr15:85114479 UBE2QP1 0.69 7.96 0.4 2.5e-14 Schizophrenia; LIHC cis rs6860806 0.507 rs2631372 chr5:131703578 C/G cg24060327 chr5:131705240 SLC22A5 -0.69 -10.36 -0.49 4.88e-22 Breast cancer; LIHC cis rs3924048 0.559 rs6541039 chr1:12626261 T/C cg00291366 chr1:12616550 NA 0.37 7.69 0.38 1.59e-13 Optic cup area; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg00280220 chr17:61926910 NA 0.42 6.81 0.35 4.44e-11 Prudent dietary pattern; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg14393609 chr7:65229607 NA 0.41 6.91 0.35 2.43e-11 Calcium levels; LIHC cis rs858239 0.632 rs6952947 chr7:23121042 C/G cg23682824 chr7:23144976 KLHL7 -0.39 -5.9 -0.3 8.9e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg04013166 chr16:89971882 TCF25 0.64 8.77 0.43 8.83e-17 Skin colour saturation; LIHC cis rs6684514 1.000 rs12132794 chr1:156281020 C/G cg16558208 chr1:156270281 VHLL -0.53 -10.13 -0.48 2.85e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs6456156 0.586 rs12198816 chr6:167483546 G/A cg23791538 chr6:167370224 RNASET2 -0.55 -8.6 -0.42 2.88e-16 Primary biliary cholangitis; LIHC cis rs9733 0.596 rs3087960 chr1:150620569 C/G cg18016565 chr1:150552671 MCL1 0.58 11.47 0.53 5.62e-26 Tonsillectomy; LIHC trans rs2363709 1.000 rs2363709 chr3:67417105 G/A cg25028035 chr6:42016671 CCND3 -0.83 -6.16 -0.32 2.04e-9 IgE levels; LIHC cis rs34779708 0.931 rs4934535 chr10:35432721 G/T cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9916302 0.904 rs4357971 chr17:37717280 C/T cg00129232 chr17:37814104 STARD3 -0.41 -6.56 -0.33 2.05e-10 Glomerular filtration rate (creatinine); LIHC cis rs7098414 0.511 rs7907575 chr10:82152675 T/G cg01528321 chr10:82214614 TSPAN14 0.43 6.49 0.33 3.08e-10 Post bronchodilator FEV1; LIHC trans rs1814175 0.616 rs1851848 chr11:49992254 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs344364 0.511 rs62040571 chr16:1948514 C/G cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg00091569 chr3:40428383 ENTPD3 -0.35 -6.09 -0.31 2.96e-9 Renal cell carcinoma; LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.71 0.76 2.62e-66 Height; LIHC cis rs4780401 0.967 rs11075012 chr16:11831030 T/C cg01061890 chr16:11836724 TXNDC11 -0.42 -6.07 -0.31 3.44e-9 Rheumatoid arthritis; LIHC cis rs11711311 1.000 rs9830978 chr3:113455940 A/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.49 9.43 0.45 6.63e-19 IgG glycosylation; LIHC trans rs637571 0.522 rs1786175 chr11:65754808 G/A cg17712092 chr4:129076599 LARP1B 0.74 13.11 0.58 4.34e-32 Eosinophil percentage of white cells; LIHC cis rs17102423 0.731 rs942629 chr14:65539318 A/G cg16583315 chr14:65563665 MAX -0.39 -7.93 -0.39 3.14e-14 Obesity-related traits; LIHC cis rs10823500 0.777 rs10509321 chr10:71985733 A/G cg04118878 chr10:71993077 PPA1 -0.57 -5.99 -0.31 5.38e-9 Blood protein levels; LIHC cis rs344364 0.511 rs337286 chr16:1965719 C/T cg26897989 chr16:1907736 C16orf73 -0.5 -5.79 -0.3 1.61e-8 Glomerular filtration rate in chronic kidney disease; LIHC cis rs9322817 0.902 rs7773123 chr6:105173726 A/G cg02098413 chr6:105308735 HACE1 0.43 7.07 0.36 9.01e-12 Thyroid stimulating hormone; LIHC cis rs477895 0.838 rs11607007 chr11:64007976 C/T cg18225595 chr11:63971243 STIP1 0.64 7.86 0.39 4.95e-14 Mean platelet volume; LIHC cis rs7903847 0.642 rs10882915 chr10:99142184 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg00656387 chr3:40428638 ENTPD3 0.41 6.77 0.34 5.55e-11 Renal cell carcinoma; LIHC cis rs1005277 0.541 rs2505193 chr10:38394638 G/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs875971 0.798 rs12698522 chr7:65967341 T/C cg18876405 chr7:65276391 NA 0.34 6.18 0.32 1.8e-9 Aortic root size; LIHC cis rs7940866 0.903 rs10791109 chr11:130850377 A/C cg12179176 chr11:130786555 SNX19 0.5 7.24 0.36 2.96e-12 Schizophrenia; LIHC cis rs9486719 1.000 rs11153018 chr6:96956137 G/A cg06623918 chr6:96969491 KIAA0776 -0.7 -7.03 -0.36 1.13e-11 Migraine;Coronary artery disease; LIHC cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg26752003 chr8:145688521 CYHR1 0.61 9.71 0.46 7.77e-20 Age at first birth; LIHC cis rs3020736 0.500 rs7364293 chr22:42506370 C/T cg04733989 chr22:42467013 NAGA -0.66 -9.47 -0.46 4.7e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs1534166 0.647 rs9853615 chr3:133519981 C/T cg27366882 chr3:133540807 NA 0.42 7.26 0.37 2.63e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs778371 0.748 rs1878287 chr2:233790649 G/T cg08000102 chr2:233561755 GIGYF2 -0.78 -7.84 -0.39 5.72e-14 Schizophrenia; LIHC cis rs9902453 0.780 rs3115093 chr17:28039755 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 12.89 0.57 3.03e-31 Coffee consumption (cups per day); LIHC cis rs8180040 0.874 rs11130123 chr3:47285912 A/G cg27129171 chr3:47204927 SETD2 0.68 11.6 0.53 1.83e-26 Colorectal cancer; LIHC cis rs1790761 0.667 rs4147581 chr11:67351585 C/G cg00290607 chr11:67383545 NA 0.39 5.91 0.3 8.17e-9 Mean corpuscular volume; LIHC cis rs769267 0.740 rs2965185 chr19:19525792 T/C cg03709012 chr19:19516395 GATAD2A 0.77 9.78 0.47 4.37e-20 Tonsillectomy; LIHC cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs3768617 0.565 rs10752897 chr1:183071024 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.33 0.49 5.93e-22 Fuchs's corneal dystrophy; LIHC cis rs1707322 1.000 rs9793167 chr1:46446800 G/A cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs72627123 0.500 rs67852564 chr14:74559920 A/G cg05179529 chr14:74551516 LIN52;ALDH6A1 0.53 7.18 0.36 4.26e-12 Morning vs. evening chronotype; LIHC cis rs9325144 0.647 rs11168819 chr12:39011082 C/A cg26384229 chr12:38710491 ALG10B -0.43 -6.07 -0.31 3.45e-9 Morning vs. evening chronotype; LIHC cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg03264133 chr6:25882463 NA 0.59 8.34 0.41 1.79e-15 Blood metabolite levels; LIHC cis rs4908768 1.000 rs7523186 chr1:8655495 C/T cg20416874 chr1:8611966 RERE -0.56 -7.44 -0.37 8.06e-13 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9388451 0.626 rs1935983 chr6:126068914 C/T cg05901451 chr6:126070800 HEY2 -0.69 -14.61 -0.62 6.62e-38 Brugada syndrome; LIHC cis rs34779708 0.966 rs4934540 chr10:35474699 T/C cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.47e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs929354 0.772 rs6957939 chr7:156978485 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs6500602 0.727 rs3761681 chr16:4566857 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 7.63 0.38 2.34e-13 Schizophrenia; LIHC cis rs965469 0.779 rs6139048 chr20:3239753 T/G cg25506879 chr20:3388711 C20orf194 -0.52 -6.33 -0.32 7.92e-10 IFN-related cytopenia; LIHC cis rs4788570 0.538 rs16973260 chr16:71534853 A/G cg06353428 chr16:71660113 MARVELD3 1.08 9.57 0.46 2.23e-19 Intelligence (multi-trait analysis); LIHC cis rs78545713 0.649 rs79662647 chr6:26217845 G/A cg16070018 chr6:26224392 HIST1H3E 0.8 7.54 0.38 4.2e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs6066825 0.644 rs6019386 chr20:47326440 T/G cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.84e-12 Colorectal cancer; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg14196208 chr9:127020110 NEK6 -0.4 -6.1 -0.31 2.93e-9 Neuroblastoma; LIHC trans rs66887589 0.616 rs1052633 chr4:120215314 A/G cg25214090 chr10:38739885 LOC399744 0.44 6.93 0.35 2.08e-11 Diastolic blood pressure; LIHC trans rs10506458 0.915 rs12426017 chr12:63396272 T/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.52 -0.49 1.27e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs738321 0.757 rs3788535 chr22:38534045 T/C cg25457927 chr22:38595422 NA -0.32 -7.34 -0.37 1.6e-12 Breast cancer; LIHC cis rs7512552 0.803 rs9436125 chr1:150487961 C/G cg15654264 chr1:150340011 RPRD2 0.72 11.25 0.52 3.55e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs1577917 1.000 rs12209127 chr6:86724427 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -9.97 -0.47 1e-20 Response to antipsychotic treatment; LIHC cis rs1707322 0.752 rs6678444 chr1:46229847 A/G cg03146154 chr1:46216737 IPP 0.56 9.01 0.44 1.47e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11718455 1.000 rs28731098 chr3:44019816 A/C cg08738300 chr3:44038990 NA 0.51 8.87 0.43 4.13e-17 Coronary artery disease; LIHC cis rs6424115 0.729 rs561733 chr1:24049595 T/G cg10978503 chr1:24200527 CNR2 0.29 6.94 0.35 1.94e-11 Immature fraction of reticulocytes; LIHC cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg01788221 chr16:89496183 ANKRD11 -0.39 -6.23 -0.32 1.35e-9 Multiple myeloma (IgH translocation); LIHC cis rs2412488 0.927 rs3811785 chr4:54327235 T/C cg22241045 chr4:54363911 LNX1 -0.42 -6.77 -0.34 5.69e-11 DNA methylation (variation); LIHC cis rs798554 0.679 rs2266922 chr7:2824707 G/A cg13628971 chr7:2884303 GNA12 0.42 6.72 0.34 7.57e-11 Height; LIHC cis rs4319547 0.695 rs11836188 chr12:122865507 T/C cg05707623 chr12:122985044 ZCCHC8 0.54 7.13 0.36 6.04e-12 Body mass index; LIHC cis rs2382817 0.580 rs6756265 chr2:219095554 G/A cg00012203 chr2:219082015 ARPC2 -0.88 -15.33 -0.64 9.23e-41 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6831352 0.837 rs2924583 chr4:100044640 T/C cg12011299 chr4:100065546 ADH4 0.62 10.4 0.49 3.54e-22 Alcohol dependence; LIHC cis rs763121 0.853 rs1569492 chr22:38975511 A/G cg06022373 chr22:39101656 GTPBP1 -0.63 -11.96 -0.54 8.62e-28 Menopause (age at onset); LIHC cis rs10463316 0.894 rs1876619 chr5:150744773 G/C cg03212797 chr5:150827313 SLC36A1 -0.45 -6.95 -0.35 1.88e-11 Metabolite levels (Pyroglutamine); LIHC cis rs8017423 0.874 rs4900029 chr14:90686257 T/A cg14092571 chr14:90743983 NA -0.37 -5.92 -0.3 7.8e-9 Mortality in heart failure; LIHC cis rs78062588 1.000 rs72999485 chr1:154559360 G/C cg24304309 chr1:154577895 ADAR -0.56 -6.41 -0.33 4.88e-10 Lung cancer; LIHC cis rs12467847 0.931 rs2708931 chr2:113693878 C/G cg12858261 chr2:113808755 IL1F8 -0.39 -6.77 -0.34 5.58e-11 Response to amphetamines; LIHC cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg13047869 chr3:10149882 C3orf24 0.55 6.5 0.33 2.83e-10 Alzheimer's disease; LIHC cis rs17817600 0.929 rs11234483 chr11:85644400 A/G cg03102841 chr11:85646010 NA -0.45 -5.92 -0.3 7.85e-9 Alzheimer's disease; LIHC cis rs12477438 0.501 rs11683188 chr2:99724512 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.58 10.6 0.5 6.89e-23 Chronic sinus infection; LIHC trans rs79976124 0.879 rs12213669 chr6:66627704 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.73 0.34 7.17e-11 Type 2 diabetes; LIHC cis rs1801251 1.000 rs1044480 chr2:233633736 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.15 0.52 7.48e-25 Coronary artery disease; LIHC cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.54 0.46 2.74e-19 Platelet count; LIHC cis rs5769765 0.955 rs5769761 chr22:50263641 G/T cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs6088590 1.000 rs6120705 chr20:33313740 T/C cg08999081 chr20:33150536 PIGU 0.37 5.78 0.3 1.67e-8 Coronary artery disease; LIHC trans rs2243480 1.000 rs2707831 chr7:66062511 G/A cg10756647 chr7:56101905 PSPH 1.01 11.98 0.54 7.24e-28 Diabetic kidney disease; LIHC cis rs9902453 0.817 rs62068620 chr17:28167674 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.19 0.55 1.29e-28 Coffee consumption (cups per day); LIHC cis rs7927592 0.913 rs10896338 chr11:68299360 G/A cg01657329 chr11:68192670 LRP5 -0.47 -6.08 -0.31 3.22e-9 Total body bone mineral density; LIHC cis rs7617773 0.780 rs13084616 chr3:48339699 A/G cg11946769 chr3:48343235 NME6 -0.88 -11.12 -0.52 9.58e-25 Coronary artery disease; LIHC cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg07308232 chr7:1071921 C7orf50 -0.47 -7.48 -0.37 6.49e-13 Longevity;Endometriosis; LIHC trans rs7178375 1.000 rs11070678 chr15:31219764 A/G cg04373760 chr16:53404718 NA 0.57 7.42 0.37 9.58e-13 Hypertriglyceridemia; LIHC cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs5769765 0.817 rs9616212 chr22:50317687 G/A cg09182678 chr22:50328711 NA -0.41 -6.08 -0.31 3.15e-9 Schizophrenia; LIHC cis rs244293 0.965 rs2529508 chr17:53212572 A/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs1003719 0.713 rs2835594 chr21:38466064 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg06481639 chr22:41940642 POLR3H 0.6 5.78 0.3 1.64e-8 Vitiligo; LIHC cis rs6912958 0.559 rs2985039 chr6:88041757 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.35 0.52 1.49e-25 Monocyte percentage of white cells; LIHC cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg11062466 chr8:58055876 NA 0.47 6.56 0.33 2.03e-10 Developmental language disorder (linguistic errors); LIHC cis rs4294134 0.832 rs12707241 chr7:135259183 T/C cg20392616 chr7:135392013 SLC13A4 0.38 5.98 0.31 5.63e-9 Paget's disease; LIHC cis rs12744310 0.945 rs72665696 chr1:41775429 G/T cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2235642 0.533 rs9922661 chr16:1605163 C/A cg03034668 chr16:1723424 CRAMP1L -0.4 -6.38 -0.33 5.79e-10 Coronary artery disease; LIHC cis rs8078723 1.000 rs4795415 chr17:38157995 C/T cg17467752 chr17:38218738 THRA 0.76 13.98 0.6 1.96e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7223966 1.000 rs7223966 chr17:61893398 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.61 0.34 1.46e-10 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs2727020 1.000 rs2727020 chr11:49111407 C/G cg03929089 chr4:120376271 NA 0.63 8.96 0.44 2.12e-17 Coronary artery disease; LIHC cis rs1664789 0.967 rs1694060 chr5:53278158 C/T ch.5.1024479R chr5:53302184 ARL15 0.51 8.26 0.41 3.17e-15 Waist circumference adjusted for body mass index; LIHC cis rs2380220 0.516 rs7748108 chr6:96008082 T/C cg23517279 chr6:96025343 MANEA 0.54 6.33 0.32 7.53e-10 Behavioural disinhibition (generation interaction); LIHC cis rs875971 0.862 rs12537823 chr7:65720884 C/T cg18252515 chr7:66147081 NA -0.45 -6.5 -0.33 2.83e-10 Aortic root size; LIHC cis rs10504229 0.906 rs7846666 chr8:58172302 T/C cg20607798 chr8:58055168 NA 0.46 5.81 0.3 1.44e-8 Developmental language disorder (linguistic errors); LIHC cis rs6783573 0.510 rs11718490 chr3:46628763 C/T cg16875182 chr3:46619291 LRRC2;TDGF1 -0.57 -6.23 -0.32 1.38e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7903847 0.596 rs869967 chr10:99147975 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs694739 0.894 rs11601860 chr11:64110422 A/T cg02228329 chr11:64053129 BAD;GPR137 0.7 9.56 0.46 2.49e-19 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs10847980 0.623 rs28613486 chr12:123867268 T/C cg07919128 chr17:18022025 MYO15A -0.76 -7.56 -0.38 3.75e-13 Adiponectin levels; LIHC cis rs7927771 1.000 rs35624992 chr11:47615798 G/C cg18512352 chr11:47633146 NA -0.26 -6.06 -0.31 3.65e-9 Subjective well-being; LIHC cis rs10791097 0.582 rs2282578 chr11:130735691 A/T cg12179176 chr11:130786555 SNX19 0.82 13.51 0.59 1.21e-33 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2066819 1.000 rs78149779 chr12:56694817 A/G cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs25645 0.771 rs10445310 chr17:38205396 C/A cg17467752 chr17:38218738 THRA -0.55 -9.31 -0.45 1.57e-18 Myeloid white cell count; LIHC cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg22105103 chr4:187893119 NA 0.33 8.29 0.41 2.6e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.614 rs35245220 chr17:56510305 G/A cg25039879 chr17:56429692 SUPT4H1 0.83 9.41 0.45 7.7e-19 Cognitive test performance; LIHC cis rs5753037 0.676 rs737945 chr22:30202774 G/C cg01021169 chr22:30184971 ASCC2 -0.42 -8.34 -0.41 1.81e-15 Type 1 diabetes; LIHC cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg25894440 chr7:65020034 NA -0.54 -6.22 -0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg09455208 chr3:40491958 NA 0.4 8.03 0.4 1.56e-14 Renal cell carcinoma; LIHC cis rs72627509 0.638 rs12642622 chr4:57902276 G/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.53 -6.9 -0.35 2.52e-11 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4319547 0.656 rs10846664 chr12:122823777 C/T cg23029597 chr12:123009494 RSRC2 0.51 7.34 0.37 1.57e-12 Body mass index; LIHC cis rs9783347 0.961 rs4150653 chr11:18374782 G/A cg15585147 chr11:18324498 HPS5 0.38 5.99 0.31 5.39e-9 Pancreatic cancer; LIHC cis rs10779751 0.879 rs7543400 chr1:11283964 C/G cg08854313 chr1:11322531 MTOR 0.87 15.75 0.65 2.09e-42 Body mass index; LIHC cis rs10128251 0.650 rs4469789 chr10:5712366 A/G cg24097872 chr10:5724021 NA 0.68 10.74 0.5 2.25e-23 Childhood ear infection; LIHC cis rs2303759 0.626 rs12982246 chr19:49801169 A/G cg05022225 chr19:49866942 DKKL1;TEAD2 0.54 8.02 0.4 1.69e-14 Multiple sclerosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22828804 chr20:3140466 UBOX5;FASTKD5 0.44 6.15 0.32 2.19e-9 Lung function (FEV1/FVC); LIHC cis rs9549328 0.800 rs9549326 chr13:113630453 C/T cg18289306 chr13:113640169 MCF2L 0.42 6.61 0.34 1.49e-10 Systolic blood pressure; LIHC cis rs4891159 0.527 rs689642 chr18:74119120 A/C cg24786174 chr18:74118243 ZNF516 0.86 17.67 0.69 4.33e-50 Longevity; LIHC cis rs7520050 0.966 rs785495 chr1:46587887 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.79 0.3 1.56e-8 Red blood cell count;Reticulocyte count; LIHC cis rs875971 0.660 rs801193 chr7:66030612 A/C cg18876405 chr7:65276391 NA -0.43 -7.77 -0.39 9.37e-14 Aortic root size; LIHC cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2637266 0.967 rs12246430 chr10:78352879 C/T cg18941641 chr10:78392320 NA 0.3 6.44 0.33 3.94e-10 Pulmonary function; LIHC cis rs12188164 0.543 rs2672722 chr5:453567 G/A cg00049323 chr5:472564 LOC25845 0.35 5.82 0.3 1.38e-8 Cystic fibrosis severity; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs8062405 0.929 rs11150609 chr16:28870596 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs763121 0.853 rs4821816 chr22:39113134 G/A cg06022373 chr22:39101656 GTPBP1 0.72 13.62 0.59 4.94e-34 Menopause (age at onset); LIHC cis rs6723226 0.764 rs176403 chr2:32637864 C/A cg02381751 chr2:32503542 YIPF4 -0.77 -11.8 -0.54 3.39e-27 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.692 rs12911902 chr15:77053575 T/C cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.9e-38 Blood metabolite levels; LIHC cis rs7927771 1.000 rs11605774 chr11:47832793 G/A cg20135002 chr11:47629003 NA -0.54 -9.25 -0.45 2.57e-18 Subjective well-being; LIHC cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg27297192 chr10:134578999 INPP5A 0.53 8.02 0.4 1.75e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg13409248 chr3:40428643 ENTPD3 0.46 7.65 0.38 2.01e-13 Renal cell carcinoma; LIHC cis rs77861329 1.000 rs9811707 chr3:52190657 G/A cg08692210 chr3:52188851 WDR51A 0.82 7.74 0.39 1.14e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs611744 0.647 rs12675265 chr8:109268805 C/T cg21045802 chr8:109455806 TTC35 0.58 10.31 0.49 6.89e-22 Dupuytren's disease; LIHC cis rs9430161 0.611 rs12081197 chr1:11034239 T/C cg27631724 chr1:11040367 C1orf127 0.37 6.83 0.35 4.01e-11 Ewing sarcoma; LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg22903471 chr2:27725779 GCKR -0.46 -8.03 -0.4 1.6e-14 Total body bone mineral density; LIHC cis rs2439831 0.850 rs7169322 chr15:44131014 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.69 0.43 1.58e-16 Lung cancer in ever smokers; LIHC cis rs17401966 0.931 rs11121545 chr1:10411211 A/G cg15208524 chr1:10270712 KIF1B 0.41 6.09 0.31 3.05e-9 Hepatocellular carcinoma; LIHC cis rs10751667 0.621 rs11246375 chr11:999620 T/C cg06064525 chr11:970664 AP2A2 -0.44 -10.79 -0.5 1.47e-23 Alzheimer's disease (late onset); LIHC cis rs9733 0.525 rs11584184 chr1:150695689 A/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs2439831 0.702 rs9989313 chr15:44152817 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.93 0.35 2.11e-11 Lung cancer in ever smokers; LIHC cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg16822855 chr3:40428330 ENTPD3 0.35 6.38 0.33 5.91e-10 Renal cell carcinoma; LIHC cis rs10197940 0.550 rs77233070 chr2:152416477 G/A cg19508488 chr2:152266495 RIF1 0.59 8.5 0.42 5.97e-16 Lung cancer; LIHC cis rs9322193 0.607 rs10457852 chr6:150201720 C/T cg01145232 chr6:150245071 RAET1G 0.39 7.39 0.37 1.14e-12 Lung cancer; LIHC cis rs921968 0.565 rs2059717 chr2:219600316 A/T cg02985541 chr2:219472218 PLCD4 -0.36 -6.22 -0.32 1.45e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21611145 chr19:13261629 IER2;STX10 0.49 6.12 0.31 2.53e-9 Lung function (FEV1/FVC); LIHC cis rs4919694 0.572 rs12261294 chr10:104934952 C/T cg04362960 chr10:104952993 NT5C2 0.8 6.9 0.35 2.59e-11 Arsenic metabolism; LIHC cis rs7953508 0.506 rs3782415 chr12:93967755 T/C cg18151635 chr12:93972918 NA -0.51 -8.58 -0.42 3.4e-16 Pubertal anthropometrics; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05980081 chr15:64385876 FAM96A -0.55 -7.01 -0.35 1.29e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10733682 0.659 rs4358894 chr9:129464802 C/G cg00232160 chr9:129468157 NA 0.36 6.26 0.32 1.16e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11608355 0.515 rs61941591 chr12:109919965 A/C cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs589448 0.933 rs2249093 chr12:69753512 G/C cg19645103 chr12:69753606 YEATS4 -0.4 -5.92 -0.3 7.74e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9733 0.715 rs7534124 chr1:150739073 C/T cg17724175 chr1:150552817 MCL1 -0.37 -7.3 -0.37 2e-12 Tonsillectomy; LIHC cis rs4780401 0.609 rs8063099 chr16:11806714 T/G cg01061890 chr16:11836724 TXNDC11 -0.65 -10.47 -0.49 1.97e-22 Rheumatoid arthritis; LIHC cis rs7586673 1.000 rs16845584 chr2:161923830 C/T cg16506815 chr2:162101123 NA -0.47 -7.78 -0.39 8.46e-14 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.818 rs7688802 chr4:120451668 G/A cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26627956 chr2:202004766 CFLAR 0.39 6.21 0.32 1.55e-9 Pancreatic cancer; LIHC cis rs12220238 0.915 rs12217890 chr10:76024496 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.24 0.32 1.28e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1198430 1.000 rs1198430 chr1:23755513 C/T cg19827787 chr1:23763612 ASAP3 -0.32 -6.1 -0.31 2.94e-9 Total cholesterol levels; LIHC cis rs2280018 0.526 rs1510148 chr16:15167379 T/A cg07549590 chr16:15018862 NA -0.41 -7.83 -0.39 6.07e-14 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4474465 0.688 rs7124803 chr11:78280822 T/G cg02023728 chr11:77925099 USP35 -0.33 -5.94 -0.31 7.02e-9 Alzheimer's disease (survival time); LIHC cis rs708547 0.647 rs1277308 chr4:57897864 C/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.49 7.13 0.36 5.96e-12 Response to bleomycin (chromatid breaks); LIHC cis rs11098499 0.691 rs12510133 chr4:120271344 A/C cg09307838 chr4:120376055 NA 0.62 9.83 0.47 3e-20 Corneal astigmatism; LIHC cis rs11577318 0.853 rs4333841 chr1:26631927 T/C cg00852783 chr1:26633632 UBXN11 0.42 6.77 0.34 5.56e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs3736228 0.522 rs111564249 chr11:68404220 G/A cg16797656 chr11:68205561 LRP5 0.49 6.24 0.32 1.3e-9 Bone mineral density; LIHC cis rs7582720 1.000 rs72932590 chr2:203884308 A/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10242455 0.571 rs73713595 chr7:99326659 G/A cg18809830 chr7:99032528 PTCD1 -0.85 -6.8 -0.34 4.79e-11 Blood metabolite levels; LIHC cis rs3820068 0.705 rs951225 chr1:15826292 G/A cg17385448 chr1:15911702 AGMAT 0.37 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs858239 0.600 rs2072368 chr7:23146112 C/T cg23682824 chr7:23144976 KLHL7 0.43 6.53 0.33 2.32e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs208520 0.874 rs208481 chr6:66922636 A/G cg07460842 chr6:66804631 NA -0.7 -7.81 -0.39 7.21e-14 Exhaled nitric oxide output; LIHC cis rs6942756 0.876 rs822039 chr7:129065774 A/G cg02491457 chr7:128862824 NA -0.6 -9.33 -0.45 1.39e-18 White matter hyperintensity burden; LIHC cis rs1401999 0.714 rs1000002 chr3:183635768 A/G cg01324343 chr3:183735012 ABCC5 -0.52 -8.31 -0.41 2.22e-15 Anterior chamber depth; LIHC trans rs1005277 0.505 rs719569 chr10:38154415 T/G cg27523141 chr10:43048294 ZNF37B -0.39 -6.86 -0.35 3.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -7.93 -0.39 3.14e-14 Type 2 diabetes; LIHC cis rs1949733 0.666 rs3103070 chr4:8508825 A/G cg11789530 chr4:8429930 ACOX3 -0.75 -11.28 -0.52 2.65e-25 Response to antineoplastic agents; LIHC cis rs7216064 1.000 rs3935969 chr17:65881959 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.69 -0.46 9.09e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9640161 0.742 rs2108852 chr7:150019628 T/C cg17279839 chr7:150038598 RARRES2 0.5 10.58 0.5 8.39e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs8064299 0.597 rs9944506 chr17:72782726 C/G cg25054828 chr17:72772726 NAT9;TMEM104 0.82 15.1 0.63 8.08e-40 Monocyte count; LIHC cis rs600806 0.888 rs3768497 chr1:109866230 T/C cg23091122 chr1:110024289 SYPL2 -0.45 -5.93 -0.31 7.4e-9 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07631383 chr7:131012765 MKLN1 0.42 6.44 0.33 4.02e-10 Cognitive function; LIHC cis rs992157 1.000 rs13429408 chr2:219142860 C/A cg00012203 chr2:219082015 ARPC2 0.86 14.26 0.61 1.62e-36 Colorectal cancer; LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg11062466 chr8:58055876 NA 0.51 6.48 0.33 3.23e-10 Developmental language disorder (linguistic errors); LIHC trans rs61931739 0.500 rs11836207 chr12:34315177 G/A cg26384229 chr12:38710491 ALG10B 0.46 6.06 0.31 3.5e-9 Morning vs. evening chronotype; LIHC cis rs2204008 0.744 rs2222344 chr12:38406832 T/G cg26384229 chr12:38710491 ALG10B 0.58 8.04 0.4 1.5e-14 Bladder cancer; LIHC cis rs8067545 0.750 rs4925085 chr17:20000131 G/T cg13482628 chr17:19912719 NA 0.49 8.03 0.4 1.6e-14 Schizophrenia; LIHC cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg18225595 chr11:63971243 STIP1 0.66 10.79 0.5 1.51e-23 Platelet count; LIHC cis rs11098499 0.863 rs10009626 chr4:120470005 T/C cg09307838 chr4:120376055 NA 0.76 11.71 0.54 7.22e-27 Corneal astigmatism; LIHC cis rs9486719 1.000 rs2273622 chr6:97058567 A/G cg06623918 chr6:96969491 KIAA0776 -0.72 -6.78 -0.34 5.45e-11 Migraine;Coronary artery disease; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17498856 chr1:1457042 ATAD3A 0.39 6.06 0.31 3.67e-9 Alopecia areata; LIHC cis rs17253792 0.822 rs17685053 chr14:56125771 T/A cg01858014 chr14:56050164 KTN1 -0.73 -8.35 -0.41 1.74e-15 Putamen volume; LIHC cis rs523522 0.673 rs643372 chr12:121022640 C/G cg12219531 chr12:120966889 COQ5 0.68 13.19 0.58 2.17e-32 High light scatter reticulocyte count; LIHC trans rs7246657 0.943 rs2291004 chr19:37997952 C/A cg10208301 chr11:6592745 DNHD1 0.45 6.04 0.31 3.92e-9 Coronary artery calcification; LIHC cis rs1577917 1.000 rs12216203 chr6:86675301 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.26 -0.49 1.06e-21 Response to antipsychotic treatment; LIHC cis rs9818758 0.607 rs9847839 chr3:49289003 T/C cg07636037 chr3:49044803 WDR6 -0.79 -8.19 -0.4 5.34e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg13409248 chr3:40428643 ENTPD3 0.43 7.21 0.36 3.51e-12 Renal cell carcinoma; LIHC cis rs1144333 0.510 rs12408897 chr1:76448102 T/C cg22875332 chr1:76189707 ACADM 0.41 6.01 0.31 4.79e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg02579736 chr3:10068473 FANCD2;CIDECP -0.9 -11.74 -0.54 5.66e-27 Alzheimer's disease; LIHC cis rs79057730 0.527 rs35316052 chr7:802954 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.79 8.86 0.43 4.49e-17 Initial pursuit acceleration; LIHC cis rs1568889 0.838 rs10835276 chr11:28167147 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.27 0.61 1.4e-36 Bipolar disorder; LIHC cis rs700651 0.685 rs976180 chr2:198880443 C/T cg03934865 chr2:198174659 NA -0.48 -7.03 -0.36 1.11e-11 Intracranial aneurysm; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16150678 chr8:101170369 SPAG1 0.41 6.06 0.31 3.64e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1005277 0.528 rs2057228 chr10:38515766 T/C cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs7872515 1.000 rs7872515 chr9:94822540 A/G cg01248375 chr9:94877805 SPTLC1 -0.54 -7.53 -0.38 4.43e-13 Bipolar disorder and schizophrenia; LIHC cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg12756686 chr19:29218302 NA 0.43 6.64 0.34 1.24e-10 Methadone dose in opioid dependence; LIHC cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg25894440 chr7:65020034 NA -0.55 -6.31 -0.32 8.76e-10 Diabetic kidney disease; LIHC cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg00106254 chr7:1943704 MAD1L1 0.37 5.79 0.3 1.58e-8 Bipolar disorder and schizophrenia; LIHC cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg00750074 chr16:89608354 SPG7 -0.38 -5.8 -0.3 1.5e-8 Multiple myeloma (IgH translocation); LIHC cis rs798554 0.567 rs1182192 chr7:2869274 G/A cg13628971 chr7:2884303 GNA12 0.38 5.88 0.3 9.73e-9 Height; LIHC cis rs6701037 0.512 rs2285216 chr1:175133012 C/T cg00321850 chr1:175162397 KIAA0040 0.45 7.33 0.37 1.66e-12 Alcohol dependence; LIHC cis rs1401999 1.000 rs9858774 chr3:183652736 G/A cg05044414 chr3:183734942 ABCC5 0.34 5.97 0.31 5.79e-9 Anterior chamber depth; LIHC cis rs561341 0.769 rs559228 chr17:30294527 T/C cg00745463 chr17:30367425 LRRC37B -0.77 -5.71 -0.3 2.43e-8 Hip circumference adjusted for BMI; LIHC cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg07308232 chr7:1071921 C7orf50 -0.54 -8.74 -0.43 1.08e-16 Longevity;Endometriosis; LIHC cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg21433313 chr16:3507492 NAT15 0.47 7.67 0.38 1.83e-13 Tuberculosis; LIHC cis rs2180341 0.960 rs7773484 chr6:127670779 T/C cg24812749 chr6:127587940 RNF146 1.05 15.38 0.64 6.23e-41 Breast cancer; LIHC cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.12 0.52 9.62e-25 Platelet count; LIHC trans rs617791 0.530 rs55947178 chr11:65754230 G/A cg17712092 chr4:129076599 LARP1B -0.56 -6.8 -0.35 4.55e-11 Breast cancer; LIHC cis rs1005277 0.603 rs1998062 chr10:38457652 G/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.57 -0.5 9e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg04234412 chr22:24373322 LOC391322 0.68 9.98 0.47 9.65e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs3813359 0.614 rs17059066 chr6:130769858 C/T cg12097325 chr1:1076431 NA -0.74 -6.04 -0.31 4.05e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7131987 0.903 rs11050163 chr12:29420398 C/T cg21522988 chr12:29376872 FAR2 0.29 6.73 0.34 7.11e-11 QT interval; LIHC cis rs6964587 0.610 rs4729008 chr7:91457054 G/T cg17063962 chr7:91808500 NA 0.63 10.59 0.5 7.19e-23 Breast cancer; LIHC cis rs763121 0.719 rs9610995 chr22:39057763 C/T cg06022373 chr22:39101656 GTPBP1 0.66 11.49 0.53 4.72e-26 Menopause (age at onset); LIHC cis rs11583043 0.874 rs41312668 chr1:101443582 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 8.3 0.41 2.45e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs763121 0.853 rs5995610 chr22:39064681 C/T cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs7927592 0.913 rs7123564 chr11:68362164 C/T cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.88e-14 Total body bone mineral density; LIHC cis rs2204008 0.615 rs11495468 chr12:38024633 C/T cg26384229 chr12:38710491 ALG10B 0.79 9.44 0.45 5.99e-19 Bladder cancer; LIHC cis rs2842992 0.915 rs1322427 chr6:160075454 C/A cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.62 0.42 2.52e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs2806561 0.765 rs1738468 chr1:23510850 T/G cg19743168 chr1:23544995 NA 0.34 5.72 0.3 2.33e-8 Height; LIHC cis rs10791097 0.694 rs2155751 chr11:130755240 G/A cg12179176 chr11:130786555 SNX19 0.79 12.44 0.56 1.43e-29 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs950776 0.518 rs12591557 chr15:78811732 A/G cg22563815 chr15:78856949 CHRNA5 0.35 6.31 0.32 8.54e-10 Sudden cardiac arrest; LIHC cis rs2839186 0.632 rs17176110 chr21:47706535 C/A cg12516959 chr21:47718080 NA -0.38 -5.96 -0.31 6.38e-9 Testicular germ cell tumor; LIHC cis rs9682041 0.696 rs6774380 chr3:170091644 T/A cg11886554 chr3:170076028 SKIL 0.66 5.99 0.31 5.18e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs240764 0.658 rs4840148 chr6:101182500 G/A cg12253828 chr6:101329408 ASCC3 -0.39 -5.97 -0.31 6.04e-9 Neuroticism; LIHC trans rs2243480 1.000 rs7787230 chr7:65629099 G/A cg10756647 chr7:56101905 PSPH -1.1 -13.4 -0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs9303280 0.806 rs9303279 chr17:38073968 G/C cg11212589 chr17:38028394 ZPBP2 -0.34 -6.64 -0.34 1.21e-10 Self-reported allergy; LIHC cis rs208520 0.690 rs6929762 chr6:66709277 C/T cg07460842 chr6:66804631 NA 0.74 8.7 0.43 1.46e-16 Exhaled nitric oxide output; LIHC cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg11890956 chr21:40555474 PSMG1 1.02 14.54 0.62 1.3e-37 Cognitive function; LIHC cis rs13191362 0.935 rs35049401 chr6:162968464 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.72 5.86 0.3 1.11e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs74181299 0.684 rs6736728 chr2:65305499 A/G cg05010058 chr2:65284262 CEP68 0.4 6.61 0.34 1.51e-10 Pulse pressure; LIHC cis rs7918232 0.830 rs7911024 chr10:27433636 A/C cg14240646 chr10:27532245 ACBD5 -0.66 -6.28 -0.32 1.02e-9 Breast cancer; LIHC cis rs7833986 0.501 rs72653962 chr8:56997505 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.06e-16 Height; LIHC cis rs7188697 0.885 rs1646010 chr16:58549204 G/C cg02549819 chr16:58548995 SETD6 -0.49 -7.74 -0.39 1.14e-13 QT interval; LIHC cis rs9733 0.544 rs72700902 chr1:150633347 C/T cg13175981 chr1:150552382 MCL1 -0.43 -5.9 -0.3 8.63e-9 Tonsillectomy; LIHC cis rs9902453 1.000 rs4581755 chr17:28427898 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.65 10.06 0.48 4.99e-21 Coffee consumption (cups per day); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10408731 chr7:65214843 CCT6P1 -0.34 -6.35 -0.32 7.04e-10 Calcium levels; LIHC cis rs11951515 0.508 rs67261887 chr5:43612441 T/A cg01983248 chr5:43482804 C5orf28 -0.4 -6.55 -0.33 2.06e-10 Metabolite levels (X-11787); LIHC cis rs2075371 1.000 rs2544210 chr7:133971535 C/T cg20476274 chr7:133979776 SLC35B4 0.76 13.14 0.58 3.4e-32 Mean platelet volume; LIHC cis rs6840360 0.967 rs6535817 chr4:152641941 G/C cg22705602 chr4:152727874 NA -0.34 -7.17 -0.36 4.67e-12 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.521 rs1376122 chr3:161087857 A/G cg03342759 chr3:160939853 NMD3 -0.43 -6.25 -0.32 1.23e-9 Morning vs. evening chronotype; LIHC cis rs4423214 0.879 rs1790324 chr11:71150520 A/C cg24826892 chr11:71159390 DHCR7 -0.44 -5.75 -0.3 1.98e-8 Vitamin D levels; LIHC cis rs17818399 0.547 rs7607633 chr2:46759427 T/C cg02822958 chr2:46747628 ATP6V1E2 0.42 6.3 0.32 9.16e-10 Height; LIHC cis rs875971 0.755 rs10228885 chr7:65780529 C/G cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs9300255 0.543 rs1617156 chr12:123590165 T/C cg05973401 chr12:123451056 ABCB9 0.47 5.97 0.31 6.06e-9 Neutrophil percentage of white cells; LIHC cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.02 0.31 4.43e-9 Menopause (age at onset); LIHC trans rs1814175 0.530 rs11040482 chr11:49727068 T/C cg03929089 chr4:120376271 NA -0.86 -16.65 -0.67 5.35e-46 Height; LIHC cis rs1816752 0.905 rs7995492 chr13:25013023 A/T cg02811702 chr13:24901961 NA 0.25 6.38 0.33 5.7e-10 Obesity-related traits; LIHC cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs365132 1.000 rs353468 chr5:176445494 A/T cg16309518 chr5:176445507 NA -0.58 -11.34 -0.52 1.62e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs400736 0.896 rs225126 chr1:8090615 A/G cg25007680 chr1:8021821 PARK7 0.6 9.52 0.46 3.23e-19 Response to antidepressants and depression; LIHC cis rs9768139 0.696 rs4909177 chr7:158117047 A/T cg25566285 chr7:158114605 PTPRN2 0.22 6.06 0.31 3.56e-9 Calcium levels; LIHC cis rs2153535 0.504 rs9405393 chr6:8467432 G/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs600806 0.713 rs12140694 chr1:109998386 C/T cg23091122 chr1:110024289 SYPL2 -0.52 -6.93 -0.35 2.04e-11 Intelligence (multi-trait analysis); LIHC cis rs6088590 0.523 rs6058084 chr20:33183804 C/T cg08999081 chr20:33150536 PIGU 0.69 13.79 0.6 1.05e-34 Coronary artery disease; LIHC cis rs4716602 0.572 rs10271030 chr7:156159796 T/C cg16983916 chr7:156159713 NA -0.32 -5.73 -0.3 2.17e-8 Anti-saccade response; LIHC cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg19774624 chr17:42201019 HDAC5 0.79 12.06 0.55 3.87e-28 Total body bone mineral density; LIHC cis rs13161895 0.941 rs438050 chr5:179414645 T/C cg02702477 chr5:179499311 RNF130 0.75 10.32 0.49 6.59e-22 LDL cholesterol; LIHC cis rs4407350 0.694 rs131163 chr22:44892135 A/G cg11695653 chr22:44894386 LDOC1L -0.35 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg24531977 chr5:56204891 C5orf35 -0.72 -10.07 -0.48 4.6e-21 Initial pursuit acceleration; LIHC cis rs2067615 0.579 rs7964605 chr12:107205413 C/T cg15890332 chr12:107067104 RFX4 -0.26 -6.1 -0.31 2.85e-9 Heart rate; LIHC cis rs1003719 0.788 rs1155785 chr21:38447939 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs763121 0.853 rs138709 chr22:39139216 C/G cg14440974 chr22:39074834 NA -0.38 -6.44 -0.33 4.04e-10 Menopause (age at onset); LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg18279126 chr7:2041391 MAD1L1 0.37 6.12 0.31 2.62e-9 Bipolar disorder and schizophrenia; LIHC trans rs1814175 0.534 rs1983448 chr11:49933856 C/A cg03929089 chr4:120376271 NA -0.84 -15.82 -0.65 1.12e-42 Height; LIHC cis rs2637266 1.000 rs10219023 chr10:78364537 G/A cg18941641 chr10:78392320 NA 0.28 5.84 0.3 1.2e-8 Pulmonary function; LIHC cis rs244293 0.868 rs12453779 chr17:53172109 G/A cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.55 0.38 4.05e-13 Menarche (age at onset); LIHC cis rs17401966 1.000 rs3748578 chr1:10420918 A/G cg19773385 chr1:10388646 KIF1B 0.5 8.51 0.42 5.47e-16 Hepatocellular carcinoma; LIHC cis rs79149102 0.579 rs8039433 chr15:75367367 T/C cg16226627 chr15:75307476 SCAMP5 0.49 8.67 0.42 1.75e-16 Lung cancer; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg19074533 chr20:25604700 NANP -0.44 -6.09 -0.31 3.12e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs9300255 0.602 rs1727317 chr12:123618942 T/C cg00376283 chr12:123451042 ABCB9 0.58 6.08 0.31 3.18e-9 Neutrophil percentage of white cells; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg00838250 chr3:186287958 TBCCD1;DNAJB11 0.42 6.13 0.31 2.47e-9 Morning vs. evening chronotype; LIHC cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg04944784 chr2:26401820 FAM59B 0.7 9.12 0.44 6.58e-18 Gut microbiome composition (summer); LIHC cis rs7847628 0.587 rs12684934 chr9:123593159 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.96 19.23 0.72 2.28e-56 Birth weight; LIHC cis rs7447593 0.666 rs10866705 chr5:176801131 G/T cg17509989 chr5:176798049 RGS14 -0.58 -9.9 -0.47 1.7e-20 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg00091569 chr3:40428383 ENTPD3 0.39 6.74 0.34 6.75e-11 Renal cell carcinoma; LIHC trans rs911555 0.713 rs10162425 chr14:103931621 C/T cg17675199 chr6:35436792 RPL10A 0.41 8.39 0.41 1.34e-15 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.791 rs383841 chr6:145888329 G/T cg13319975 chr6:146136371 FBXO30 0.41 6.65 0.34 1.19e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs35306767 0.715 rs1250891 chr10:1040159 G/C cg26597838 chr10:835615 NA 0.9 8.51 0.42 5.42e-16 Eosinophil percentage of granulocytes; LIHC cis rs57590327 0.612 rs820272 chr3:81554345 T/C cg07356753 chr3:81810745 GBE1 0.42 5.77 0.3 1.74e-8 Extraversion; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15464645 chr15:28380110 HERC2 0.41 6.08 0.31 3.24e-9 Pancreatic cancer; LIHC trans rs11098499 0.863 rs7678400 chr4:120461957 G/A cg25214090 chr10:38739885 LOC399744 0.61 9.85 0.47 2.6e-20 Corneal astigmatism; LIHC trans rs2727020 0.658 rs1851992 chr11:49438110 C/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.45 -0.72 2.74e-57 Coronary artery disease; LIHC cis rs2576037 0.526 rs7240239 chr18:44460037 T/C cg19077165 chr18:44547161 KATNAL2 -0.43 -6.6 -0.34 1.56e-10 Personality dimensions; LIHC cis rs2153535 0.601 rs7741024 chr6:8530313 T/C cg23788917 chr6:8435910 SLC35B3 0.64 9.08 0.44 8.77e-18 Motion sickness; LIHC cis rs722599 0.639 rs2193596 chr14:75234101 A/C cg11812906 chr14:75593930 NEK9 0.4 5.88 0.3 9.68e-9 IgG glycosylation; LIHC cis rs6988636 1.000 rs17323510 chr8:124186089 A/G cg15893493 chr8:124194847 FAM83A -0.83 -7.9 -0.39 3.77e-14 Urinary uromodulin levels; LIHC cis rs6570726 0.935 rs906774 chr6:145813770 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.84 0.47 2.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 0.964 rs7546237 chr1:46285610 A/C cg03146154 chr1:46216737 IPP 0.48 7.8 0.39 7.74e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17401966 0.931 rs746881 chr1:10346810 C/T cg19773385 chr1:10388646 KIF1B 0.4 7.16 0.36 5.01e-12 Hepatocellular carcinoma; LIHC cis rs2576037 0.526 rs626217 chr18:44429182 T/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.64 9.85 0.47 2.5e-20 Personality dimensions; LIHC cis rs68170813 0.559 rs78404515 chr7:106909126 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.9 -0.3 8.7e-9 Coronary artery disease; LIHC cis rs7095607 0.606 rs4746739 chr10:69960091 C/T cg18986048 chr10:69913749 MYPN -0.38 -5.74 -0.3 2.1e-8 Lung function (FVC); LIHC cis rs1401999 0.628 rs1520195 chr3:183736882 G/A cg01324343 chr3:183735012 ABCC5 0.6 9.65 0.46 1.25e-19 Anterior chamber depth; LIHC cis rs637571 0.544 rs56239996 chr11:65730003 A/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.82 0.43 5.99e-17 Eosinophil percentage of white cells; LIHC cis rs12479064 0.724 rs3087403 chr2:100058870 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.62 -7.74 -0.39 1.11e-13 Chronic sinus infection; LIHC cis rs10791097 0.694 rs7106684 chr11:130758153 A/T cg12179176 chr11:130786555 SNX19 0.88 14.59 0.62 7.91e-38 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs1568889 1.000 rs12802830 chr11:28321196 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.47 6.45 0.33 3.92e-10 Bipolar disorder; LIHC cis rs826838 0.904 rs10880981 chr12:38763911 G/A cg26384229 chr12:38710491 ALG10B 1.04 13.79 0.6 1.09e-34 Heart rate; LIHC cis rs10463316 0.817 rs7701271 chr5:150776708 A/G cg03212797 chr5:150827313 SLC36A1 0.41 6.07 0.31 3.41e-9 Metabolite levels (Pyroglutamine); LIHC cis rs9902453 0.933 rs7224199 chr17:28523726 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.75 0.43 1.02e-16 Coffee consumption (cups per day); LIHC cis rs7903847 0.544 rs61861865 chr10:99144867 C/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7833986 0.501 rs2953898 chr8:56980803 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.84 8.6 0.42 2.96e-16 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01939414 chr2:103353548 MFSD9 0.47 6.47 0.33 3.39e-10 Pancreatic cancer; LIHC cis rs921968 0.541 rs17572485 chr2:219296545 C/T cg02176678 chr2:219576539 TTLL4 -0.57 -7.94 -0.39 2.89e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs807029 0.577 rs7903239 chr10:102758337 G/T cg17130504 chr10:102756923 LZTS2 0.55 7.56 0.38 3.84e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4450131 0.569 rs7917674 chr10:126340267 C/A cg20435097 chr10:126320824 FAM53B -0.62 -11.66 -0.53 1.14e-26 White blood cell count (basophil); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg02375201 chr1:27114675 PIGV -0.52 -6.3 -0.32 9.09e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs919433 0.617 rs12619333 chr2:198567638 C/G cg03934865 chr2:198174659 NA -0.48 -7.01 -0.35 1.27e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs757110 0.770 rs11024268 chr11:17387982 A/G cg15432903 chr11:17409602 KCNJ11 0.65 10.1 0.48 3.62e-21 Type 2 diabetes; LIHC cis rs2439831 0.681 rs511673 chr15:43618863 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.78 11.88 0.54 1.79e-27 Lung cancer in ever smokers; LIHC cis rs10791097 0.694 rs2155751 chr11:130755240 G/A cg22079354 chr11:130786696 SNX19 0.42 5.95 0.31 6.52e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs3892630 0.817 rs12609866 chr19:33184412 C/T cg22980127 chr19:33182716 NUDT19 1.04 12.44 0.56 1.48e-29 Red blood cell traits; LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg13752114 chr3:195489708 MUC4 0.7 11.48 0.53 5.24e-26 Lung disease severity in cystic fibrosis; LIHC cis rs12791968 0.765 rs11038250 chr11:45009114 A/G cg11846598 chr11:44996168 LOC221122 -0.42 -6.71 -0.34 8.06e-11 Inhibitory control; LIHC cis rs2066819 1.000 rs1274493 chr12:56682371 C/T cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Psoriasis vulgaris; LIHC cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg20295408 chr7:1910781 MAD1L1 -0.44 -6.49 -0.33 3.09e-10 Bipolar disorder and schizophrenia; LIHC cis rs4934494 0.727 rs55823491 chr10:91517355 A/G cg19698084 chr10:91461284 KIF20B -0.44 -5.83 -0.3 1.31e-8 Red blood cell count; LIHC cis rs1865760 0.568 rs2032450 chr6:25993114 C/G cg18357526 chr6:26021779 HIST1H4A 0.41 6.13 0.31 2.36e-9 Height; LIHC cis rs11971779 0.680 rs10085902 chr7:139109105 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs2180341 0.814 rs6919082 chr6:127737888 T/G cg24812749 chr6:127587940 RNF146 0.78 11.99 0.54 6.63e-28 Breast cancer; LIHC cis rs1577917 0.771 rs2475791 chr6:86368164 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.55 -0.56 5.53e-30 Response to antipsychotic treatment; LIHC cis rs6089829 0.962 rs4809456 chr20:61660849 C/A cg08564027 chr20:61660810 NA 0.4 7.68 0.38 1.66e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs1198430 0.714 rs946265 chr1:23775296 T/G cg19827787 chr1:23763612 ASAP3 0.3 6.45 0.33 3.74e-10 Total cholesterol levels; LIHC cis rs2016586 0.767 rs879680 chr22:36130527 T/C cg26342177 chr22:36113512 APOL5 -0.36 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs10752881 1.000 rs10752883 chr1:182980963 G/A ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg23806715 chr17:73775811 H3F3B 0.54 7.63 0.38 2.39e-13 Psoriasis; LIHC cis rs9309473 0.950 rs10169213 chr2:73787234 G/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs56235845 0.964 rs11741640 chr5:176792743 G/A cg17509989 chr5:176798049 RGS14 0.88 13.01 0.58 1.06e-31 Hemoglobin concentration;Hematocrit; LIHC cis rs9457247 0.663 rs2282860 chr6:167440244 T/C cg23791538 chr6:167370224 RNASET2 -0.61 -10.55 -0.5 1.05e-22 Crohn's disease; LIHC cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg25894440 chr7:65020034 NA -0.51 -5.78 -0.3 1.69e-8 Diabetic kidney disease; LIHC trans rs1814175 0.616 rs6486011 chr11:49740230 C/T cg15704280 chr7:45808275 SEPT13 -0.97 -20.37 -0.74 5.91e-61 Height; LIHC cis rs1881396 0.945 rs1881397 chr2:27832285 A/G cg27432699 chr2:27873401 GPN1 0.43 6.52 0.33 2.47e-10 Nonalcoholic fatty liver disease; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg09581848 chr17:37909335 NA 0.43 6.44 0.33 4.02e-10 Immature fraction of reticulocytes; LIHC trans rs10506458 0.915 rs17763441 chr12:63418335 T/C cg22491629 chr6:157744540 C6orf35 -0.58 -10.57 -0.5 8.45e-23 Hemostatic factors and hematological phenotypes; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03513682 chr16:85542749 NA 0.46 6.74 0.34 6.95e-11 Longevity; LIHC cis rs10949834 0.529 rs7785826 chr7:73548785 C/A cg07137043 chr7:73588983 EIF4H -0.67 -7.15 -0.36 5.45e-12 Verbal memory performance (residualized delayed recall change); LIHC cis rs72781680 1.000 rs72781663 chr2:24221694 C/G cg08917208 chr2:24149416 ATAD2B 0.85 7.69 0.38 1.59e-13 Lymphocyte counts; LIHC cis rs7843479 0.601 rs4422769 chr8:21844265 A/G cg17168535 chr8:21777572 XPO7 0.6 10.44 0.49 2.46e-22 Mean corpuscular volume; LIHC cis rs7617773 0.539 rs13087050 chr3:48392800 C/T cg11946769 chr3:48343235 NME6 0.54 6.68 0.34 9.59e-11 Coronary artery disease; LIHC cis rs597539 0.615 rs629426 chr11:68671104 A/G cg04772025 chr11:68637568 NA 0.45 5.95 0.31 6.7e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs60871478 0.730 rs13222476 chr7:826630 T/C cg27478167 chr7:817139 HEATR2 -0.5 -6.78 -0.34 5.4e-11 Cerebrospinal P-tau181p levels; LIHC cis rs1577917 0.958 rs10944168 chr6:86680156 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.1 -0.48 3.7e-21 Response to antipsychotic treatment; LIHC cis rs9372253 1.000 rs11153232 chr6:110716252 G/T cg19196401 chr6:110721138 DDO 0.32 6.43 0.33 4.19e-10 Platelet distribution width; LIHC cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg18230493 chr5:56204884 C5orf35 -0.46 -6.36 -0.33 6.64e-10 Initial pursuit acceleration; LIHC cis rs40363 0.645 rs250627 chr16:3527050 G/A cg05754148 chr16:3507555 NAT15 0.39 5.92 0.3 8e-9 Tuberculosis; LIHC cis rs11690935 0.959 rs6709156 chr2:172591944 T/C cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.78 -0.69 1.57e-50 Schizophrenia; LIHC cis rs7412746 0.658 rs2230061 chr1:150727539 G/A cg15448220 chr1:150897856 SETDB1 0.44 6.74 0.34 6.63e-11 Melanoma; LIHC cis rs10883723 0.962 rs10883726 chr10:104236276 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 11.37 0.52 1.22e-25 Allergic disease (asthma, hay fever or eczema); LIHC cis rs11122272 0.735 rs2749708 chr1:231529610 G/A cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC trans rs7246657 0.943 rs10415937 chr19:37830064 T/G cg10208301 chr11:6592745 DNHD1 0.47 6.89 0.35 2.68e-11 Coronary artery calcification; LIHC cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg05555928 chr11:63887634 MACROD1 0.53 7.08 0.36 8.01e-12 Mean platelet volume; LIHC trans rs7726839 0.540 rs3749618 chr5:602650 A/G cg25482853 chr8:67687455 SGK3 0.6 6.05 0.31 3.86e-9 Obesity-related traits; LIHC cis rs4716602 0.596 rs10265909 chr7:156158095 T/C cg16983916 chr7:156159713 NA -0.32 -5.87 -0.3 1.03e-8 Anti-saccade response; LIHC cis rs9368481 0.502 rs3933232 chr6:26877446 T/C cg12292205 chr6:26970375 C6orf41 0.42 7.07 0.36 8.58e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs9611519 0.780 rs9611527 chr22:41644428 G/A cg06481639 chr22:41940642 POLR3H -0.51 -5.74 -0.3 2.14e-8 Neuroticism; LIHC cis rs477692 1.000 rs565974 chr10:131423274 C/T cg19680672 chr10:131412579 MGMT -0.45 -6.86 -0.35 3.33e-11 Response to temozolomide; LIHC cis rs747782 0.527 rs1044269 chr11:47487740 G/A cg20307385 chr11:47447363 PSMC3 0.59 6.89 0.35 2.63e-11 Intraocular pressure; LIHC cis rs6840360 0.593 rs3805356 chr4:152680701 C/T cg22705602 chr4:152727874 NA 0.37 7.76 0.39 9.77e-14 Intelligence (multi-trait analysis); LIHC cis rs10791323 0.569 rs2298738 chr11:133715153 G/C cg06766960 chr11:133703094 NA -0.7 -11.44 -0.53 6.83e-26 Childhood ear infection; LIHC cis rs6598955 0.724 rs12132137 chr1:26631243 C/T cg00852783 chr1:26633632 UBXN11 0.54 8.89 0.43 3.5e-17 Obesity-related traits; LIHC cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg03806693 chr22:41940476 POLR3H -0.97 -10.84 -0.51 1.01e-23 Vitiligo; LIHC cis rs9394841 0.646 rs9369313 chr6:41847065 C/T cg17623882 chr6:41773611 USP49 -0.43 -5.8 -0.3 1.53e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs9399137 0.507 rs4896129 chr6:135349845 C/T cg24558204 chr6:135376177 HBS1L 0.62 10.72 0.5 2.68e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg11062466 chr8:58055876 NA 0.45 6.12 0.31 2.5e-9 Developmental language disorder (linguistic errors); LIHC cis rs9513627 1.000 rs7338537 chr13:100119581 C/A cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs7116495 1.000 rs562469 chr11:71569843 A/T cg26138937 chr11:71823887 C11orf51 0.7 6.7 0.34 8.52e-11 Severe influenza A (H1N1) infection; LIHC cis rs79149102 0.579 rs59303424 chr15:75370014 G/A cg09165964 chr15:75287851 SCAMP5 -0.55 -7.22 -0.36 3.48e-12 Lung cancer; LIHC cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs6952808 0.575 rs6950330 chr7:1953606 T/C cg21782813 chr7:2030301 MAD1L1 0.44 7.45 0.37 7.57e-13 Bipolar disorder and schizophrenia; LIHC trans rs61931739 0.500 rs7489270 chr12:34432062 C/T cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs1008375 1.000 rs60178264 chr4:17685308 G/T cg02297831 chr4:17616191 MED28 0.43 6.8 0.35 4.6e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs1005277 0.579 rs2505194 chr10:38393881 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.13 0.31 2.38e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs709400 0.663 rs1022736 chr14:103998423 G/C cg26031613 chr14:104095156 KLC1 0.77 9.35 0.45 1.2e-18 Body mass index; LIHC cis rs1401999 1.000 rs6800217 chr3:183685893 T/C cg05044414 chr3:183734942 ABCC5 0.35 6.11 0.31 2.76e-9 Anterior chamber depth; LIHC cis rs5769765 0.954 rs5770709 chr22:50245196 G/T cg02269571 chr22:50332266 NA 0.59 8.34 0.41 1.83e-15 Schizophrenia; LIHC cis rs9910055 0.552 rs4793084 chr17:42317371 G/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.58 -8.62 -0.42 2.56e-16 Total body bone mineral density; LIHC cis rs9303401 0.538 rs3785493 chr17:56472119 G/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.86 -10.82 -0.51 1.16e-23 Cognitive test performance; LIHC cis rs1144333 0.655 rs76612182 chr1:76451889 C/T cg22875332 chr1:76189707 ACADM 0.43 6.43 0.33 4.35e-10 Attention function in attention deficit hyperactive disorder; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg05064044 chr6:292385 DUSP22 -0.57 -7.85 -0.39 5.52e-14 Menopause (age at onset); LIHC cis rs2412488 0.927 rs7690908 chr4:54339423 A/G cg22241045 chr4:54363911 LNX1 -0.42 -6.71 -0.34 8.2e-11 DNA methylation (variation); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22109331 chr1:212003961 LPGAT1 0.45 6.08 0.31 3.21e-9 Lung function (FEV1/FVC); LIHC cis rs6788895 1.000 rs2014279 chr3:150487945 G/T cg07663535 chr3:150480033 SIAH2 0.5 6.42 0.33 4.51e-10 Breast cancer; LIHC cis rs7592578 0.679 rs62181020 chr2:191325601 A/C cg27211696 chr2:191398769 TMEM194B -0.52 -6.84 -0.35 3.71e-11 Diastolic blood pressure; LIHC cis rs9534463 0.667 rs1747224 chr13:47223102 G/A cg04092803 chr13:47240378 LRCH1 0.27 5.74 0.3 2.11e-8 Platelet distribution width; LIHC cis rs17152411 0.793 rs12569669 chr10:126592671 A/G cg07906193 chr10:126599966 NA 0.47 7.25 0.37 2.75e-12 Height; LIHC cis rs9918079 0.542 rs12499412 chr4:15602252 G/C cg04067612 chr4:15429572 C1QTNF7 0.28 5.87 0.3 1.03e-8 Obesity-related traits; LIHC cis rs7552404 1.000 rs28602663 chr1:76235355 C/T cg03433033 chr1:76189801 ACADM 0.68 9.31 0.45 1.57e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1555322 0.505 rs639763 chr20:33861904 C/T cg17927777 chr20:33865990 NA 0.53 6.1 0.31 2.87e-9 Attention deficit hyperactivity disorder; LIHC cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg05025164 chr4:1340916 KIAA1530 0.43 6.63 0.34 1.3e-10 Obesity-related traits; LIHC cis rs9837602 0.507 rs793453 chr3:99529095 A/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.4 -5.71 -0.3 2.41e-8 Breast cancer; LIHC cis rs8081395 0.805 rs2645485 chr17:57944281 C/G cg13753209 chr17:57696993 CLTC 0.39 5.81 0.3 1.44e-8 White blood cell count; LIHC cis rs3018712 0.547 rs4930583 chr11:68411179 G/A cg16797656 chr11:68205561 LRP5 -0.44 -5.83 -0.3 1.28e-8 Total body bone mineral density; LIHC cis rs13427251 0.868 rs1901284 chr2:100146040 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.5 6.28 0.32 1.01e-9 Chronic sinus infection; LIHC cis rs6942756 0.659 rs624118 chr7:129096653 C/T cg02491457 chr7:128862824 NA -0.55 -8.63 -0.42 2.35e-16 White matter hyperintensity burden; LIHC cis rs509477 1.000 rs7236052 chr18:32574540 A/G cg23791764 chr18:32556832 MAPRE2 -0.49 -6.76 -0.34 6.07e-11 Cerebrospinal fluid AB1-42 levels; LIHC cis rs2066819 0.901 rs1274490 chr12:56649601 A/G cg26714650 chr12:56694279 CS 1.12 13.15 0.58 2.97e-32 Psoriasis vulgaris; LIHC trans rs66887589 0.616 rs6822808 chr4:120217365 C/A cg25214090 chr10:38739885 LOC399744 0.44 6.88 0.35 2.86e-11 Diastolic blood pressure; LIHC cis rs4721295 0.573 rs3779000 chr7:2181628 G/A cg04267008 chr7:1944627 MAD1L1 -0.5 -7.62 -0.38 2.48e-13 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs9467711 0.606 rs9379897 chr6:26601526 T/C cg09904177 chr6:26538194 HMGN4 -0.53 -5.72 -0.3 2.37e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs7146395 1 rs7146395 chr14:75228647 A/C cg08847533 chr14:75593920 NEK9 0.48 7.44 0.37 8.33e-13 Platelet count; LIHC cis rs9611565 0.546 rs34077262 chr22:42061639 A/G cg03806693 chr22:41940476 POLR3H 0.82 9.35 0.45 1.15e-18 Vitiligo; LIHC trans rs71658797 0.505 rs12041509 chr1:77969621 T/G cg04606550 chr5:14226569 TRIO 0.39 6.04 0.31 4.06e-9 Lung cancer in ever smokers;Lung cancer;Lung adenocarcinoma; LIHC cis rs12478296 1.000 rs60533128 chr2:243028088 A/G cg05760424 chr2:242988095 NA -0.53 -6.98 -0.35 1.51e-11 Obesity-related traits; LIHC cis rs9902453 0.817 rs2617881 chr17:28063275 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.73 -11.97 -0.54 7.97e-28 Coffee consumption (cups per day); LIHC cis rs2274273 0.837 rs6573010 chr14:55721592 T/C cg04306507 chr14:55594613 LGALS3 0.35 6.54 0.33 2.24e-10 Protein biomarker; LIHC cis rs10771431 0.597 rs10843144 chr12:9357577 C/T cg08997352 chr12:9597637 DDX12 -0.5 -7.74 -0.39 1.16e-13 Breast size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21395782 chr19:19626814 NDUFA13;TSSK6 0.41 6.32 0.32 8.34e-10 Cognitive function; LIHC cis rs1866706 1.000 rs6486063 chr11:12869497 C/G cg25843174 chr11:12811716 TEAD1 0.29 6.2 0.32 1.59e-9 Intelligence (multi-trait analysis); LIHC cis rs11190604 1.000 rs3750626 chr10:102266316 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.15 0.4 6.94e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1538970 1.000 rs9326141 chr1:45828943 A/G cg24296786 chr1:45957014 TESK2 0.48 6.91 0.35 2.35e-11 Platelet count; LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg27094323 chr7:1216898 NA -0.4 -5.8 -0.3 1.53e-8 Longevity;Endometriosis; LIHC cis rs1559088 0.847 rs10423531 chr19:33600140 T/C cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7546668 1.000 rs4233537 chr1:15849700 T/A cg11706911 chr1:15910989 AGMAT 0.44 6.83 0.35 3.91e-11 Glomerular filtration rate (creatinine); LIHC cis rs7927771 0.524 rs3758655 chr11:47703943 T/C cg20307385 chr11:47447363 PSMC3 0.77 11.58 0.53 2.15e-26 Subjective well-being; LIHC cis rs35883536 0.626 rs34752753 chr1:101045193 T/G cg14515779 chr1:101123966 NA 0.49 7.06 0.36 9.19e-12 Monocyte count; LIHC cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg16606324 chr3:10149918 C3orf24 0.53 5.8 0.3 1.55e-8 Alzheimer's disease; LIHC cis rs9303401 0.659 rs62083436 chr17:57031742 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.28 0.58 9.81e-33 Cognitive test performance; LIHC cis rs875971 1.000 rs2420591 chr7:65912381 T/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.81 -0.3 1.42e-8 Menopause (age at onset); LIHC cis rs10865541 0.778 rs10779975 chr2:3420032 A/G cg11642891 chr2:3452563 TTC15 -0.45 -7.2 -0.36 3.8e-12 Obesity-related traits; LIHC cis rs11098499 0.913 rs12186259 chr4:120152039 C/T cg09307838 chr4:120376055 NA 0.69 9.83 0.47 2.99e-20 Corneal astigmatism; LIHC cis rs2976388 0.692 rs2978983 chr8:143765842 A/G cg06565975 chr8:143823917 SLURP1 0.33 6.27 0.32 1.11e-9 Urinary tract infection frequency; LIHC cis rs910316 1.000 rs910316 chr14:75626042 A/C cg11812906 chr14:75593930 NEK9 0.72 14.0 0.6 1.6e-35 Height; LIHC cis rs10508774 1.000 rs10159899 chr10:32955315 T/G cg01819863 chr10:32635814 EPC1 0.64 5.95 0.31 6.81e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4700695 0.668 rs20768 chr5:65484805 C/T cg21114390 chr5:65439923 SFRS12 -0.56 -7.92 -0.39 3.36e-14 Facial morphology (factor 19); LIHC cis rs2279817 0.913 rs11203436 chr1:18019016 T/C cg21791023 chr1:18019539 ARHGEF10L 0.65 8.02 0.4 1.71e-14 Neuroticism; LIHC cis rs7520050 0.581 rs6671303 chr1:46629653 A/C cg08160980 chr1:46668840 C1orf190;POMGNT1 -0.52 -8.01 -0.4 1.82e-14 Red blood cell count;Reticulocyte count; LIHC cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg18357526 chr6:26021779 HIST1H4A 0.58 8.01 0.4 1.85e-14 Blood metabolite levels; LIHC trans rs877282 0.842 rs35872126 chr10:764545 G/A cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs5769765 0.908 rs9616376 chr22:50310829 A/G cg09182678 chr22:50328711 NA -0.43 -6.17 -0.32 1.98e-9 Schizophrenia; LIHC cis rs9325144 0.647 rs34963631 chr12:38912260 T/A cg26384229 chr12:38710491 ALG10B -0.56 -7.66 -0.38 1.91e-13 Morning vs. evening chronotype; LIHC cis rs3749237 0.595 rs4855877 chr3:49448527 T/C cg07636037 chr3:49044803 WDR6 0.49 7.49 0.38 5.73e-13 Resting heart rate; LIHC cis rs1552244 0.882 rs3846168 chr3:9996925 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.1 -0.44 7.84e-18 Alzheimer's disease; LIHC cis rs17253792 0.822 rs75437558 chr14:56066798 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs9326778 0.520 rs17161799 chr5:108826124 A/G cg17395555 chr5:108820864 NA -0.36 -6.26 -0.32 1.19e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs7131987 0.650 rs16934135 chr12:29483963 T/G cg05697976 chr12:29376483 FAR2 0.31 6.17 0.32 1.9e-9 QT interval; LIHC cis rs919433 0.963 rs2043016 chr2:198146381 C/T cg10820045 chr2:198174542 NA -0.61 -10.23 -0.48 1.37e-21 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7520050 0.966 rs1707304 chr1:46598269 C/A cg03146154 chr1:46216737 IPP -0.37 -6.14 -0.31 2.32e-9 Red blood cell count;Reticulocyte count; LIHC cis rs736408 0.648 rs2268023 chr3:52819327 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.45 7.28 0.37 2.24e-12 Bipolar disorder; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg13409248 chr3:40428643 ENTPD3 0.47 7.67 0.38 1.84e-13 Renal cell carcinoma; LIHC cis rs10791323 0.604 rs2250025 chr11:133710914 G/A cg06766960 chr11:133703094 NA -0.67 -11.15 -0.52 7.7e-25 Childhood ear infection; LIHC cis rs9916302 0.904 rs3964723 chr17:37403979 C/T cg00129232 chr17:37814104 STARD3 -0.41 -6.56 -0.33 2.03e-10 Glomerular filtration rate (creatinine); LIHC cis rs7075426 0.669 rs10887607 chr10:88190354 A/G cg07322936 chr10:88137208 NA 0.48 6.14 0.31 2.35e-9 Migraine without aura; LIHC cis rs12908161 0.960 rs11633450 chr15:85307287 C/T cg17507749 chr15:85114479 UBE2QP1 0.61 6.79 0.34 5.09e-11 Schizophrenia; LIHC cis rs9916302 0.660 rs665413 chr17:37455678 T/A cg07936489 chr17:37558343 FBXL20 0.85 12.11 0.55 2.57e-28 Glomerular filtration rate (creatinine); LIHC cis rs6912958 0.559 rs499373 chr6:88042062 A/T cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.12 0.36 6.28e-12 Monocyte percentage of white cells; LIHC cis rs6840360 1.000 rs1366909 chr4:152588421 A/C cg22705602 chr4:152727874 NA -0.3 -6.23 -0.32 1.35e-9 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.927 rs3787427 chr20:60579789 T/C cg06108461 chr20:60628389 TAF4 -0.89 -13.83 -0.6 7.09e-35 Body mass index; LIHC cis rs10022260 1 rs10022260 chr4:83793921 C/T cg00595051 chr4:83955429 COPS4 -0.48 -6.74 -0.34 6.69e-11 Adult asthma; LIHC cis rs73001065 0.901 rs73002956 chr19:19578743 A/G cg03709012 chr19:19516395 GATAD2A 0.9 7.61 0.38 2.65e-13 LDL cholesterol; LIHC cis rs7172677 0.768 rs2304901 chr15:75340722 G/A cg09165964 chr15:75287851 SCAMP5 0.5 6.96 0.35 1.76e-11 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs61990749 0.571 rs4903655 chr14:78306326 C/G cg23188588 chr14:78226832 SNW1;C14orf178 0.49 7.39 0.37 1.12e-12 Fibroblast growth factor basic levels; LIHC cis rs1008375 0.966 rs3796812 chr4:17582051 G/A cg16339924 chr4:17578868 LAP3 0.46 6.31 0.32 8.55e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs742115 0.563 rs12663475 chr6:11297296 T/C cg25250968 chr6:11318770 NEDD9 -0.42 -6.55 -0.33 2.13e-10 Coronary artery disease; LIHC cis rs10751667 0.666 rs7934963 chr11:957220 C/T ch.11.42038R chr11:967971 AP2A2 0.54 9.76 0.47 5.28e-20 Alzheimer's disease (late onset); LIHC cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.71 0.34 8.08e-11 Bipolar disorder; LIHC cis rs2522056 1.000 rs2522062 chr5:131805416 A/G cg24060327 chr5:131705240 SLC22A5 0.55 7.44 0.37 8.01e-13 Lymphocyte counts;Fibrinogen; LIHC cis rs7487075 0.930 rs4076484 chr12:46833912 C/G cg11331445 chr12:47219877 SLC38A4 0.27 5.79 0.3 1.63e-8 Itch intensity from mosquito bite; LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg18306943 chr3:40428807 ENTPD3 0.42 7.37 0.37 1.31e-12 Renal cell carcinoma; LIHC trans rs9929218 0.906 rs9932679 chr16:68751904 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -8.95 -0.44 2.37e-17 Colorectal cancer; LIHC cis rs2228479 0.541 rs12918575 chr16:89811151 A/G cg00800038 chr16:89945340 TCF25 -0.62 -9.43 -0.45 6.49e-19 Skin colour saturation; LIHC cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg16606324 chr3:10149918 C3orf24 0.53 5.77 0.3 1.73e-8 Alzheimer's disease; LIHC cis rs6121246 0.909 rs3203770 chr20:30382315 A/G cg13852791 chr20:30311386 BCL2L1 0.92 9.63 0.46 1.39e-19 Mean corpuscular hemoglobin; LIHC cis rs4908768 0.501 rs2045820 chr1:8738135 A/G cg20416874 chr1:8611966 RERE -0.63 -12.77 -0.57 8.45e-31 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg10755058 chr3:40428713 ENTPD3 0.41 6.8 0.35 4.63e-11 Renal cell carcinoma; LIHC cis rs79976124 0.879 rs17511467 chr6:66627293 T/C cg07460842 chr6:66804631 NA 0.64 6.77 0.34 5.66e-11 Type 2 diabetes; LIHC cis rs477692 0.905 rs563859 chr10:131417586 T/C cg05714579 chr10:131428358 MGMT 0.48 8.16 0.4 6.37e-15 Response to temozolomide; LIHC cis rs2191566 0.960 rs367209 chr19:44506249 A/G cg20607764 chr19:44506953 ZNF230 0.42 6.71 0.34 7.99e-11 Acute lymphoblastic leukemia (childhood); LIHC trans rs17685 0.672 rs1639623 chr7:75707951 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.04 0.72 1.3e-55 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.68 0.8 5.83e-78 Prudent dietary pattern; LIHC cis rs16858210 0.529 rs10937154 chr3:183569489 C/T cg25686905 chr3:183603175 PARL -0.47 -8.35 -0.41 1.76e-15 Menopause (age at onset); LIHC cis rs2576037 0.501 rs7227700 chr18:44537102 T/G cg19077165 chr18:44547161 KATNAL2 -0.45 -6.82 -0.35 4.11e-11 Personality dimensions; LIHC cis rs12980942 0.872 rs3816052 chr19:41773797 C/T cg25627403 chr19:41769009 HNRNPUL1 0.51 6.38 0.33 5.74e-10 Coronary artery disease; LIHC cis rs1005277 0.579 rs1780116 chr10:38526621 C/T cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.87 -0.3 1.01e-8 Extrinsic epigenetic age acceleration; LIHC cis rs60871478 1.000 rs4720930 chr7:808073 G/A cg05535760 chr7:792225 HEATR2 0.8 11.36 0.52 1.4e-25 Cerebrospinal P-tau181p levels; LIHC cis rs910316 0.737 rs2098251 chr14:75492696 G/A cg08847533 chr14:75593920 NEK9 0.89 18.09 0.7 8.88e-52 Height; LIHC cis rs10256972 0.630 rs10282584 chr7:1081442 C/T cg23978390 chr7:1156363 C7orf50 0.48 6.83 0.35 3.86e-11 Longevity;Endometriosis; LIHC cis rs4407350 0.870 rs2213373 chr22:44911669 C/T cg04154583 chr22:44889756 LDOC1L 0.3 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg05368731 chr17:41323189 NBR1 0.72 12.06 0.55 3.69e-28 Menopause (age at onset); LIHC cis rs875971 0.862 rs778680 chr7:65840414 G/A cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs2075371 0.933 rs1421482 chr7:133964383 A/G cg11752832 chr7:134001865 SLC35B4 0.51 8.02 0.4 1.66e-14 Mean platelet volume; LIHC cis rs11098499 0.954 rs7687843 chr4:120421211 C/T cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC trans rs8073060 0.963 rs11080353 chr17:33871281 C/T cg19694781 chr19:47549865 TMEM160 0.67 7.23 0.36 3.09e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs826838 1.000 rs826851 chr12:39112639 A/G cg13010199 chr12:38710504 ALG10B -0.45 -6.36 -0.33 6.5e-10 Heart rate; LIHC cis rs6424115 0.793 rs2502998 chr1:24198327 T/A cg15997130 chr1:24165203 NA 0.38 7.78 0.39 8.76e-14 Immature fraction of reticulocytes; LIHC trans rs950169 0.614 rs12911536 chr15:84673030 G/T cg24036039 chr1:3397125 ARHGEF16 0.39 6.45 0.33 3.82e-10 Schizophrenia; LIHC cis rs6500602 0.727 rs10451135 chr16:4580214 T/C cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.92 0.3 7.95e-9 Schizophrenia; LIHC cis rs1552244 0.554 rs34883592 chr3:10046165 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs9814567 1.000 rs7611611 chr3:134307877 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.45e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7572733 0.515 rs35730302 chr2:198818626 A/T cg00792783 chr2:198669748 PLCL1 -0.46 -6.77 -0.34 5.68e-11 Dermatomyositis; LIHC cis rs7529073 0.815 rs1431983 chr1:214148772 A/C cg24083324 chr1:214162604 PROX1 0.55 8.61 0.42 2.8e-16 Schizophrenia; LIHC cis rs6732160 0.691 rs6728147 chr2:73423490 A/G cg24220031 chr2:73402428 NA 0.27 5.77 0.3 1.76e-8 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.714 rs2495278 chr6:160123674 G/A cg11366901 chr6:160182831 ACAT2 0.95 15.67 0.65 4.22e-42 Age-related macular degeneration (geographic atrophy); LIHC cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg06634786 chr22:41940651 POLR3H -0.75 -7.7 -0.38 1.49e-13 Vitiligo; LIHC cis rs17685 0.753 rs11972240 chr7:75694079 A/C cg01364799 chr7:75623366 TMEM120A -0.52 -7.9 -0.39 3.85e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4727027 0.801 rs12666337 chr7:148796253 C/T cg23583168 chr7:148888333 NA -0.7 -9.81 -0.47 3.58e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs10779751 1.000 rs12120734 chr1:11262020 A/G cg08854313 chr1:11322531 MTOR 0.86 15.36 0.64 7.44e-41 Body mass index; LIHC cis rs6456156 0.586 rs911632 chr6:167471461 T/C cg12798992 chr6:167411361 FGFR1OP 0.44 6.8 0.34 4.81e-11 Primary biliary cholangitis; LIHC cis rs6502050 0.835 rs11077981 chr17:80147243 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.78 -0.3 1.64e-8 Life satisfaction; LIHC trans rs12220238 0.841 rs10824161 chr10:76133762 C/G cg15970666 chr2:162095662 NA -0.55 -6.27 -0.32 1.09e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -10.49 -0.49 1.7e-22 Platelet count; LIHC cis rs360798 0.512 rs17027429 chr2:63079983 C/T cg17519650 chr2:63277830 OTX1 0.44 6.89 0.35 2.66e-11 Coronary artery disease; LIHC cis rs1005277 0.522 rs289648 chr10:37971837 T/C cg00409905 chr10:38381863 ZNF37A -0.56 -9.56 -0.46 2.38e-19 Extrinsic epigenetic age acceleration; LIHC cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.45 0.33 3.79e-10 Mean platelet volume; LIHC trans rs916888 0.821 rs199512 chr17:44857352 T/C cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9768139 0.708 rs896779 chr7:158113390 T/G cg25566285 chr7:158114605 PTPRN2 0.22 6.02 0.31 4.4e-9 Calcium levels; LIHC cis rs1816752 0.905 rs7339140 chr13:25011902 A/G cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.78e-10 Obesity-related traits; LIHC cis rs2629540 0.766 rs10794177 chr10:126407409 G/C cg08799069 chr10:126477246 METTL10 0.48 7.56 0.38 3.75e-13 Cocaine dependence; LIHC cis rs716804 0.703 rs11042703 chr11:10288235 G/A cg01453529 chr11:10209919 SBF2 -0.29 -5.87 -0.3 1.01e-8 Neuroticism; LIHC cis rs7772486 0.875 rs1331644 chr6:146398660 T/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.81 -0.3 1.46e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.754 rs4896839 chr6:146019689 T/G cg23711669 chr6:146136114 FBXO30 -0.74 -13.34 -0.59 5.69e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 0.688 rs7645137 chr3:10020549 A/AT cg00149659 chr3:10157352 C3orf10 0.53 6.07 0.31 3.4e-9 Alzheimer's disease; LIHC trans rs1728785 1.000 rs698716 chr16:68560296 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.08 0.31 3.28e-9 Ulcerative colitis; LIHC cis rs798554 0.797 rs1182184 chr7:2872446 G/A cg19346786 chr7:2764209 NA -0.43 -6.09 -0.31 3.07e-9 Height; LIHC cis rs5769765 0.671 rs138833 chr22:50178917 A/G cg02269571 chr22:50332266 NA -0.54 -7.41 -0.37 9.94e-13 Schizophrenia; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs244293 0.965 rs244287 chr17:53232036 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.18 0.36 4.37e-12 Menarche (age at onset); LIHC cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg23978390 chr7:1156363 C7orf50 0.54 8.13 0.4 8.1e-15 Longevity;Endometriosis; LIHC cis rs798766 1.000 rs2166580 chr4:1743169 G/A cg21231739 chr4:1642635 FAM53A -0.38 -5.98 -0.31 5.67e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg11890956 chr21:40555474 PSMG1 -0.47 -7.65 -0.38 2.13e-13 Cognitive function; LIHC cis rs317689 0.690 rs317646 chr12:69657145 A/G cg22834771 chr12:69754056 YEATS4 0.39 5.97 0.31 6.04e-9 Response to diuretic therapy; LIHC cis rs875971 0.706 rs1643374 chr7:65872682 T/A cg11764359 chr7:65958608 NA 0.64 8.71 0.43 1.31e-16 Aortic root size; LIHC cis rs922107 0.713 rs10922668 chr1:90043236 A/G cg15422784 chr1:90023713 LRRC8B -0.47 -7.6 -0.38 2.96e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg12373951 chr3:133503437 NA 0.43 7.16 0.36 4.83e-12 Iron status biomarkers; LIHC cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs365132 0.875 rs2940521 chr5:176339209 A/C cg16309518 chr5:176445507 NA -0.52 -9.6 -0.46 1.78e-19 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs9359856 0.564 rs34766278 chr6:90397132 G/C cg13799429 chr6:90582589 CASP8AP2 -0.71 -6.72 -0.34 7.52e-11 Bipolar disorder; LIHC cis rs7772486 0.846 rs2748496 chr6:146321829 T/A cg13319975 chr6:146136371 FBXO30 -0.35 -5.9 -0.3 8.87e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs734999 0.588 rs2843401 chr1:2528133 T/C cg18854424 chr1:2615690 NA -0.33 -7.27 -0.37 2.4e-12 Ulcerative colitis; LIHC cis rs6952808 0.575 rs6950330 chr7:1953606 T/C cg04267008 chr7:1944627 MAD1L1 -0.63 -10.06 -0.48 4.98e-21 Bipolar disorder and schizophrenia; LIHC cis rs782590 0.818 rs2627765 chr2:55883317 G/T cg03859395 chr2:55845619 SMEK2 0.77 13.24 0.58 1.4e-32 Metabolic syndrome; LIHC cis rs8177179 0.967 rs4994581 chr3:133437563 T/C cg24879335 chr3:133465180 TF 0.46 10.69 0.5 3.32e-23 Iron status biomarkers (transferrin levels); LIHC cis rs2073499 0.935 rs28365992 chr3:50340996 T/C cg03645007 chr3:50255295 SLC38A3 0.53 7.13 0.36 5.91e-12 Schizophrenia; LIHC cis rs2404602 0.647 rs4886837 chr15:77156417 A/G cg23625390 chr15:77176239 SCAPER -0.57 -9.76 -0.47 5.37e-20 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07016325 chr14:96968745 PAPOLA -0.43 -6.22 -0.32 1.45e-9 Cognitive function; LIHC cis rs12530845 0.673 rs73721607 chr7:135335822 C/T cg23117316 chr7:135346802 PL-5283 -0.4 -5.89 -0.3 9.38e-9 Red blood cell traits; LIHC cis rs2932538 0.922 rs34531155 chr1:113141550 C/T cg22162597 chr1:113214053 CAPZA1 0.72 9.64 0.46 1.33e-19 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7224685 0.501 rs2054038 chr17:4014391 A/C cg11204139 chr17:3907470 NA 0.67 11.3 0.52 2.3e-25 Type 2 diabetes; LIHC cis rs829883 0.668 rs829882 chr12:98880099 A/G cg23471612 chr12:98897216 NA 0.31 5.9 0.3 8.8e-9 Colorectal adenoma (advanced); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10477989 chr11:68039601 C11orf24 0.5 6.96 0.35 1.75e-11 Lung function (FEV1/FVC); LIHC cis rs28374715 0.528 rs28492932 chr15:41624397 G/C cg18705301 chr15:41695430 NDUFAF1 -1.21 -16.78 -0.67 1.55e-46 Ulcerative colitis; LIHC cis rs57221529 0.766 rs17563576 chr5:560476 A/G cg09021430 chr5:549028 NA -0.45 -9.09 -0.44 8.22e-18 Lung disease severity in cystic fibrosis; LIHC cis rs2153535 0.580 rs2327050 chr6:8440630 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg03264133 chr6:25882463 NA 0.5 6.21 0.32 1.55e-9 Intelligence (multi-trait analysis); LIHC cis rs561341 1.000 rs7210970 chr17:30262169 G/A cg13647721 chr17:30228624 UTP6 0.67 6.62 0.34 1.38e-10 Hip circumference adjusted for BMI; LIHC cis rs7592578 0.766 rs62182865 chr2:191434180 T/C cg27211696 chr2:191398769 TMEM194B -0.62 -7.86 -0.39 5.06e-14 Diastolic blood pressure; LIHC trans rs9747201 1.000 rs56051385 chr17:80126712 T/C cg07393940 chr7:158741817 NA -0.57 -6.73 -0.34 7.07e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg10811681 chr14:69259722 ZFP36L1 -0.81 -6.24 -0.32 1.29e-9 Mild influenza (H1N1) infection; LIHC cis rs3816788 0.792 rs729180 chr8:21817245 C/T cg17168535 chr8:21777572 XPO7 0.6 10.34 0.49 5.56e-22 Lung cancer in ever smokers; LIHC cis rs2404602 0.716 rs17364076 chr15:76760891 C/T cg03037974 chr15:76606532 NA 0.77 15.52 0.64 1.78e-41 Blood metabolite levels; LIHC cis rs921968 0.541 rs636723 chr2:219373197 A/G cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs3917254 0.596 rs6754776 chr2:102764778 C/G cg22835712 chr2:102737379 NA -0.5 -5.74 -0.3 2.11e-8 Blood protein levels; LIHC cis rs6733011 0.508 rs12712041 chr2:99522059 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.57 -0.33 1.83e-10 Bipolar disorder; LIHC cis rs892961 0.806 rs35489990 chr17:75412312 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs763121 0.819 rs138700 chr22:39129999 A/G cg14440974 chr22:39074834 NA -0.36 -6.04 -0.31 4.04e-9 Menopause (age at onset); LIHC cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs34779708 0.966 rs113170867 chr10:35450147 C/T cg03585969 chr10:35415529 CREM 0.86 12.87 0.57 3.46e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4474465 1.000 rs4944202 chr11:78189558 T/C cg02023728 chr11:77925099 USP35 0.33 5.85 0.3 1.13e-8 Alzheimer's disease (survival time); LIHC cis rs4665809 1.000 rs2384321 chr2:26290054 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.77 -9.42 -0.45 6.74e-19 Gut microbiome composition (summer); LIHC cis rs60871478 0.588 rs56205589 chr7:910419 G/A cg05535760 chr7:792225 HEATR2 -0.81 -6.58 -0.34 1.77e-10 Cerebrospinal P-tau181p levels; LIHC cis rs8114671 0.562 rs2273683 chr20:33509523 C/T cg07148914 chr20:33460835 GGT7 0.65 9.77 0.47 4.95e-20 Height; LIHC cis rs6582630 0.502 rs4385963 chr12:38295264 G/A cg26384229 chr12:38710491 ALG10B 0.59 8.13 0.4 7.95e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs7044106 0.791 rs735109 chr9:123488879 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.58 8.94 0.44 2.54e-17 Hip circumference adjusted for BMI; LIHC cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg00149659 chr3:10157352 C3orf10 0.65 6.97 0.35 1.63e-11 Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13645767 chr9:97766849 C9orf3 0.43 6.21 0.32 1.52e-9 Lung function (FEV1/FVC); LIHC cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg12311346 chr5:56204834 C5orf35 -0.55 -7.3 -0.37 2.02e-12 Initial pursuit acceleration; LIHC trans rs2727020 0.729 rs2299650 chr11:49174007 A/C cg18944383 chr4:111397179 ENPEP 0.25 6.14 0.32 2.28e-9 Coronary artery disease; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg24209194 chr3:40518798 ZNF619 -0.51 -7.82 -0.39 6.69e-14 Renal cell carcinoma; LIHC cis rs6840360 0.517 rs4399967 chr4:152729312 T/A cg22705602 chr4:152727874 NA 0.39 8.14 0.4 7.25e-15 Intelligence (multi-trait analysis); LIHC cis rs7447593 0.666 rs12659266 chr5:176807197 C/T cg06060754 chr5:176797920 RGS14 0.7 10.64 0.5 4.98e-23 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs9902453 0.691 rs140701 chr17:28538532 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.5 7.68 0.38 1.71e-13 Coffee consumption (cups per day); LIHC cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 0.89 12.67 0.57 1.99e-30 Alzheimer's disease; LIHC cis rs600231 0.706 rs4244811 chr11:65320780 G/A cg17120908 chr11:65337727 SSSCA1 0.46 6.63 0.34 1.28e-10 Bone mineral density; LIHC cis rs7703744 0.747 rs6896559 chr5:118678718 G/C cg04195774 chr5:118677172 TNFAIP8 -0.4 -5.72 -0.3 2.27e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1198430 0.852 rs909537 chr1:23810063 C/G cg13183780 chr1:23809682 ASAP3 -0.56 -8.08 -0.4 1.14e-14 Total cholesterol levels; LIHC cis rs2295359 0.892 rs10789224 chr1:67605134 C/T cg12940439 chr1:67600707 NA -0.39 -7.1 -0.36 7.48e-12 Psoriasis; LIHC cis rs9517313 0.897 rs4772087 chr13:99115041 A/G cg07423050 chr13:99094983 FARP1 0.56 9.96 0.47 1.05e-20 Neuroticism; LIHC cis rs7223966 1.000 rs11658175 chr17:61923838 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.73 0.34 7.34e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.53 -8.95 -0.44 2.35e-17 Bipolar disorder; LIHC trans rs9929218 0.529 rs8060790 chr16:68729112 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.9 20.34 0.74 7.47e-61 Colorectal cancer; LIHC cis rs7914558 0.966 rs10786745 chr10:104956827 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.71 -0.43 1.31e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7412746 0.658 rs11581757 chr1:150892244 A/G cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC trans rs5756813 0.754 rs4821711 chr22:38181115 C/T cg19894588 chr14:64061835 NA -0.63 -8.76 -0.43 9.13e-17 Optic cup area;Vertical cup-disc ratio; LIHC cis rs76419734 0.510 rs12504088 chr4:106662004 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.78 9.01 0.44 1.52e-17 Post bronchodilator FEV1; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.62 -0.42 2.55e-16 Lymphocyte counts; LIHC cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg00750074 chr16:89608354 SPG7 -0.49 -7.7 -0.38 1.44e-13 Multiple myeloma (IgH translocation); LIHC cis rs7927771 0.524 rs6485773 chr11:47763509 A/G cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02439053 chr19:18390991 JUND 0.43 6.05 0.31 3.81e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10779751 0.734 rs6701726 chr1:11126941 C/T cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs2274273 0.624 rs7151581 chr14:55788445 A/G cg01864836 chr14:55583639 NA 0.37 6.02 0.31 4.45e-9 Protein biomarker; LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.15e-11 Prudent dietary pattern; LIHC cis rs7618501 0.633 rs9853222 chr3:50022926 T/C cg21467203 chr3:49911342 NA -0.44 -7.79 -0.39 7.94e-14 Intelligence (multi-trait analysis); LIHC cis rs11758351 1.000 rs16891405 chr6:26204506 A/G cg03785755 chr6:26196794 NA 0.52 5.82 0.3 1.37e-8 Gout;Renal underexcretion gout; LIHC cis rs11229555 0.645 rs1986404 chr11:58194614 T/C cg15696309 chr11:58395628 NA -0.65 -7.67 -0.38 1.76e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs11122272 0.735 rs2749716 chr1:231486908 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.95 -0.51 4.11e-24 Hemoglobin concentration; LIHC cis rs1506636 1.000 rs641491 chr7:123399726 C/A cg03229431 chr7:123269106 ASB15 0.61 12.1 0.55 2.67e-28 Plateletcrit;Platelet count; LIHC cis rs950169 0.887 rs3860265 chr15:84945185 C/T cg03959625 chr15:84868606 LOC388152 0.47 6.76 0.34 6.14e-11 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06584407 chr1:11907324 NPPA 0.45 6.67 0.34 1.02e-10 Pancreatic cancer; LIHC cis rs7927592 0.956 rs12271290 chr11:68326236 A/G cg01657329 chr11:68192670 LRP5 0.47 6.32 0.32 8.04e-10 Total body bone mineral density; LIHC cis rs7959452 0.590 rs10878974 chr12:69781528 C/G cg22834771 chr12:69754056 YEATS4 -0.52 -9.23 -0.45 2.82e-18 Blood protein levels; LIHC cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg18252515 chr7:66147081 NA -1.25 -16.77 -0.67 1.7e-46 Diabetic kidney disease; LIHC cis rs8078723 0.546 rs8067817 chr17:38163936 C/T cg17467752 chr17:38218738 THRA 0.64 11.78 0.54 4.19e-27 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg04234412 chr22:24373322 LOC391322 0.74 11.52 0.53 3.52e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7249142 0.527 rs12975096 chr19:19279409 G/T cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.06 -0.31 3.58e-9 IgG glycosylation; LIHC cis rs295137 0.752 rs10931892 chr2:201104997 C/T cg23649088 chr2:200775458 C2orf69 -0.48 -6.6 -0.34 1.59e-10 Asthma (bronchodilator response); LIHC cis rs7103648 1.000 rs10838709 chr11:47447346 C/T cg20307385 chr11:47447363 PSMC3 1.04 18.97 0.72 2.46e-55 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg06634786 chr22:41940651 POLR3H 0.8 8.9 0.43 3.22e-17 Vitiligo; LIHC cis rs3091242 0.933 rs28530483 chr1:25740847 A/C cg23205692 chr1:25664452 TMEM50A 0.39 6.32 0.32 7.94e-10 Erythrocyte sedimentation rate; LIHC cis rs9612 1.000 rs28446957 chr19:44246600 T/A cg08581076 chr19:44259116 C19orf61 0.66 8.41 0.41 1.15e-15 Exhaled nitric oxide output; LIHC cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg00343986 chr7:65444356 GUSB 0.44 6.19 0.32 1.7e-9 Aortic root size; LIHC cis rs2070433 0.528 rs68063691 chr21:47759237 T/C cg12379764 chr21:47803548 PCNT 0.76 10.85 0.51 9.46e-24 Lymphocyte counts; LIHC cis rs12477438 0.501 rs6727749 chr2:99793590 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs7615952 0.800 rs2062773 chr3:125639648 T/C cg05084668 chr3:125655381 ALG1L -0.6 -8.83 -0.43 5.43e-17 Blood pressure (smoking interaction); LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg24209194 chr3:40518798 ZNF619 -0.64 -9.72 -0.47 6.96e-20 Renal cell carcinoma; LIHC cis rs7428 0.527 rs1061782 chr2:85546615 A/G cg24342717 chr2:85555507 TGOLN2 0.79 10.37 0.49 4.24e-22 Ear protrusion; LIHC cis rs6748734 0.948 rs9973366 chr2:241838151 T/C cg09990169 chr2:241835740 C2orf54 -0.7 -11.19 -0.52 5.69e-25 Urinary metabolites; LIHC cis rs34172651 0.917 rs17771137 chr16:24792242 G/A cg00339695 chr16:24857497 SLC5A11 0.54 8.14 0.4 7.45e-15 Intelligence (multi-trait analysis); LIHC trans rs877282 0.947 rs4133015 chr10:774131 T/C cg22713356 chr15:30763199 NA 1.11 10.18 0.48 1.9e-21 Uric acid levels; LIHC cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs6912958 0.559 rs376633 chr6:88042785 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.24 0.36 2.93e-12 Monocyte percentage of white cells; LIHC trans rs1814175 0.588 rs7481648 chr11:49754910 A/G cg03929089 chr4:120376271 NA -0.85 -16.54 -0.67 1.44e-45 Height; LIHC cis rs6088580 0.634 rs6059866 chr20:33075810 A/C cg08999081 chr20:33150536 PIGU 0.58 11.38 0.52 1.2e-25 Glomerular filtration rate (creatinine); LIHC cis rs2282802 0.685 rs2053055 chr5:139646776 C/T cg26211634 chr5:139558579 C5orf32 0.38 5.96 0.31 6.36e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg21448741 chr8:58168803 NA 0.33 5.86 0.3 1.11e-8 Developmental language disorder (linguistic errors); LIHC cis rs3018712 0.590 rs4930236 chr11:68414000 C/A cg16797656 chr11:68205561 LRP5 -0.43 -5.74 -0.3 2.05e-8 Total body bone mineral density; LIHC cis rs12220238 0.915 rs11001003 chr10:76099944 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2115630 0.645 rs2292463 chr15:85175750 A/G cg11189052 chr15:85197271 WDR73 -0.54 -8.27 -0.41 3.07e-15 P wave terminal force; LIHC cis rs28493229 0.522 rs2287692 chr19:41289756 G/A cg21869046 chr19:41225005 ITPKC 0.45 6.35 0.32 6.97e-10 Kawasaki disease; LIHC cis rs12477438 0.765 rs2309521 chr2:99592069 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.24 -0.41 3.62e-15 Chronic sinus infection; LIHC cis rs35110281 0.659 rs11702544 chr21:45091861 C/T cg04455712 chr21:45112962 RRP1B 0.54 9.3 0.45 1.65e-18 Mean corpuscular volume; LIHC cis rs523522 0.962 rs10849758 chr12:120971149 C/T cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs992157 0.798 rs2382818 chr2:219155907 A/T cg00012203 chr2:219082015 ARPC2 -0.83 -13.16 -0.58 2.79e-32 Colorectal cancer; LIHC cis rs7044106 0.718 rs10616 chr9:123363533 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.72 11.18 0.52 6.17e-25 Hip circumference adjusted for BMI; LIHC cis rs12477438 0.765 rs6749059 chr2:99591021 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.15 -16.95 -0.68 3.18e-47 Chronic sinus infection; LIHC trans rs1814175 0.791 rs11040513 chr11:49778153 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.85 0.35 3.39e-11 Height; LIHC cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg04546413 chr19:29218101 NA 0.54 10.5 0.49 1.53e-22 Methadone dose in opioid dependence; LIHC cis rs6499255 1.000 rs6499255 chr16:69830328 A/G cg15192750 chr16:69999425 NA 0.45 7.05 0.36 1.02e-11 IgE levels; LIHC cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg10802521 chr3:52805072 NEK4 -0.43 -6.99 -0.35 1.4e-11 Bipolar disorder; LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg06873352 chr17:61820015 STRADA 0.75 13.58 0.59 6.97e-34 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04109349 chr1:245317172 KIF26B 0.41 6.71 0.34 8.2e-11 Cognitive function; LIHC cis rs7246657 0.823 rs4802236 chr19:37919246 A/G cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg27211696 chr2:191398769 TMEM194B 0.66 10.88 0.51 6.96e-24 Pulse pressure; LIHC cis rs1005277 0.505 rs200910 chr10:38108176 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.5 -0.46 3.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg20887711 chr4:1340912 KIAA1530 0.49 7.17 0.36 4.57e-12 Longevity; LIHC cis rs539514 0.587 rs689418 chr13:76322977 G/A cg04757411 chr13:76259545 LMO7 -0.41 -6.83 -0.35 3.79e-11 Type 1 diabetes; LIHC cis rs1707322 0.717 rs2991989 chr1:46082965 C/T cg24296786 chr1:45957014 TESK2 0.4 5.71 0.3 2.44e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg24549020 chr5:56110836 MAP3K1 0.5 6.49 0.33 3.09e-10 Initial pursuit acceleration; LIHC cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6449957 0.590 rs7713645 chr5:67527326 A/C cg23036683 chr5:67512108 NA 0.4 5.83 0.3 1.28e-8 Cleft lip with or without cleft palate; LIHC cis rs34330 0.562 rs10845615 chr12:12863470 C/T cg09462578 chr12:12878428 APOLD1 -0.78 -10.44 -0.49 2.47e-22 Systemic lupus erythematosus; LIHC cis rs875971 1.000 rs6961990 chr7:65888570 C/A cg18876405 chr7:65276391 NA 0.37 6.64 0.34 1.22e-10 Aortic root size; LIHC cis rs2070488 0.965 rs4679060 chr3:38536261 T/C cg24069376 chr3:38537580 EXOG -0.43 -8.0 -0.4 1.98e-14 Electrocardiographic conduction measures; LIHC cis rs9790314 1.000 rs4273380 chr3:160950314 A/G cg04691961 chr3:161091175 C3orf57 -0.4 -6.26 -0.32 1.16e-9 Morning vs. evening chronotype; LIHC trans rs4906332 1.000 rs55930273 chr14:103960298 G/A cg17675199 chr6:35436792 RPL10A 0.35 6.89 0.35 2.76e-11 Coronary artery disease; LIHC cis rs9768139 0.901 rs56113702 chr7:158117938 C/T cg25566285 chr7:158114605 PTPRN2 -0.25 -7.55 -0.38 4.09e-13 Calcium levels; LIHC cis rs965469 0.779 rs6051771 chr20:3328271 A/G cg25506879 chr20:3388711 C20orf194 -0.53 -6.54 -0.33 2.22e-10 IFN-related cytopenia; LIHC cis rs1577917 1.000 rs7760207 chr6:86721700 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.14 -0.48 2.63e-21 Response to antipsychotic treatment; LIHC trans rs7618501 1.000 rs6446295 chr3:49809063 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.81 15.13 0.63 5.93e-40 Intelligence (multi-trait analysis); LIHC cis rs9811920 0.638 rs793471 chr3:99546335 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.13 0.36 6.18e-12 Axial length; LIHC cis rs10791097 0.694 rs7125622 chr11:130743388 T/C cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4665809 1.000 rs17040322 chr2:26351274 G/C cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs7635838 0.718 rs2249051 chr3:11403234 G/A cg00170343 chr3:11313890 ATG7 0.49 7.89 0.39 4.13e-14 HDL cholesterol; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02737830 chr12:64616354 C12orf66 0.41 6.78 0.34 5.39e-11 Cognitive function; LIHC cis rs35306767 0.903 rs12240651 chr10:943656 A/G cg20503657 chr10:835505 NA 1.08 12.16 0.55 1.63e-28 Eosinophil percentage of granulocytes; LIHC cis rs600806 0.778 rs4970731 chr1:109995459 T/C cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.11 -0.36 6.87e-12 Intelligence (multi-trait analysis); LIHC cis rs910316 0.967 rs175451 chr14:75589729 C/T cg08847533 chr14:75593920 NEK9 -0.9 -19.53 -0.73 1.37e-57 Height; LIHC cis rs600806 0.888 rs4603158 chr1:109879549 C/T cg23091122 chr1:110024289 SYPL2 -0.48 -6.46 -0.33 3.67e-10 Intelligence (multi-trait analysis); LIHC cis rs965469 0.843 rs6051698 chr20:3248983 T/C cg25506879 chr20:3388711 C20orf194 -0.53 -6.5 -0.33 2.84e-10 IFN-related cytopenia; LIHC cis rs9322817 0.902 rs9391238 chr6:105197874 A/G cg02098413 chr6:105308735 HACE1 -0.37 -6.03 -0.31 4.33e-9 Thyroid stimulating hormone; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg14257396 chr1:107603778 NA -0.38 -6.22 -0.32 1.41e-9 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs7668874 0.779 rs6848473 chr4:116811112 C/T cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs7534824 0.625 rs61780321 chr1:101428304 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 7.04 0.36 1.05e-11 Refractive astigmatism; LIHC cis rs9814567 1.000 rs4334685 chr3:134304335 T/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11122272 0.735 rs2572254 chr1:231512593 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.4 0.45 7.89e-19 Hemoglobin concentration; LIHC cis rs875971 0.660 rs1860470 chr7:66103694 G/C cg18876405 chr7:65276391 NA -0.45 -7.88 -0.39 4.37e-14 Aortic root size; LIHC cis rs3741404 0.594 rs11231704 chr11:63898182 C/T cg18225595 chr11:63971243 STIP1 -0.48 -6.34 -0.32 7.39e-10 Platelet count; LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg00656387 chr3:40428638 ENTPD3 0.49 8.3 0.41 2.38e-15 Renal cell carcinoma; LIHC cis rs3741404 0.791 rs7102177 chr11:63909228 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.95 16.09 0.66 9.11e-44 Platelet count; LIHC cis rs2010672 0.500 rs7171218 chr15:91152085 T/G cg26821196 chr15:91095069 CRTC3 0.34 6.27 0.32 1.08e-9 Sum eosinophil basophil counts;Eosinophil percentage of white cells;Eosinophil counts; LIHC cis rs16958440 0.867 rs79420880 chr18:44663687 C/T cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs372883 0.648 rs2832297 chr21:30742996 A/C cg24692254 chr21:30365293 RNF160 0.54 7.0 0.35 1.36e-11 Pancreatic cancer; LIHC cis rs8062405 1.000 rs55719896 chr16:28846866 G/A cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7312933 0.558 rs11181483 chr12:42798384 G/C cg17420585 chr12:42539391 GXYLT1 -0.35 -5.74 -0.3 2.08e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg25894440 chr7:65020034 NA -0.51 -5.74 -0.3 2.09e-8 Diabetic kidney disease; LIHC cis rs7395581 0.918 rs10838692 chr11:47345100 T/C cg26139080 chr11:47293733 MADD -0.5 -8.45 -0.42 8.46e-16 HDL cholesterol; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14022721 chr22:25507536 KIAA1671 0.37 6.11 0.31 2.67e-9 Cognitive function; LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg00106254 chr7:1943704 MAD1L1 -0.48 -8.01 -0.4 1.84e-14 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.522 rs1968127 chr7:66056803 C/T cg14393609 chr7:65229607 NA -0.38 -6.04 -0.31 4.02e-9 Aortic root size; LIHC cis rs35306767 0.761 rs1871621 chr10:1049596 C/T cg20503657 chr10:835505 NA 0.83 7.99 0.4 2.07e-14 Eosinophil percentage of granulocytes; LIHC cis rs6754311 0.552 rs1030765 chr2:136553188 A/T cg07305463 chr2:136567211 LCT 0.41 7.33 0.37 1.72e-12 Mosquito bite size; LIHC cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg11890956 chr21:40555474 PSMG1 0.97 13.01 0.58 1.05e-31 Cognitive function; LIHC cis rs483180 0.512 rs598685 chr1:120215269 G/A cg19096424 chr1:120255104 PHGDH 0.63 7.9 0.39 3.98e-14 Macular telangiectasia type 2; LIHC cis rs9457247 0.740 rs13195812 chr6:167443902 C/T cg07741184 chr6:167504864 NA 0.32 7.14 0.36 5.68e-12 Crohn's disease; LIHC cis rs9388451 0.874 rs13209968 chr6:126089285 G/C cg05901451 chr6:126070800 HEY2 -0.76 -17.49 -0.69 2.24e-49 Brugada syndrome; LIHC cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC trans rs12620999 1.000 rs10803655 chr2:238075551 C/T cg15676719 chr1:167598521 RCSD1 -0.39 -6.91 -0.35 2.42e-11 Systemic lupus erythematosus; LIHC cis rs11585357 0.793 rs112597506 chr1:17628832 A/G cg08277548 chr1:17600880 PADI3 -0.63 -6.76 -0.34 5.79e-11 Hair shape; LIHC cis rs2070433 0.556 rs8129460 chr21:47822544 C/T cg12379764 chr21:47803548 PCNT 0.69 10.11 0.48 3.39e-21 Lymphocyte counts; LIHC cis rs7772486 0.764 rs9399569 chr6:146242942 C/T cg23711669 chr6:146136114 FBXO30 -0.62 -10.89 -0.51 6.65e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs11888559 0.511 rs1351826 chr2:203850508 G/A cg24605529 chr2:203879461 NBEAL1 0.72 5.77 0.3 1.74e-8 Height; LIHC cis rs12701220 0.894 rs10263252 chr7:1049949 G/A cg00990874 chr7:1149470 C7orf50 -0.66 -9.21 -0.45 3.26e-18 Bronchopulmonary dysplasia; LIHC cis rs25645 0.502 rs7209742 chr17:38108708 A/G cg17467752 chr17:38218738 THRA 0.4 6.05 0.31 3.79e-9 Myeloid white cell count; LIHC cis rs11229555 0.645 rs11229435 chr11:58185796 G/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7551222 0.691 rs4951077 chr1:204482262 G/A cg20240347 chr1:204465584 NA -0.35 -7.48 -0.37 6.51e-13 Schizophrenia; LIHC cis rs12144094 0.882 rs1853048 chr1:120240114 C/A cg20995928 chr1:120229863 NA 0.42 7.26 0.37 2.59e-12 Height; LIHC cis rs1371867 0.875 rs1660344 chr8:101324659 A/G cg06636551 chr8:101224915 SPAG1 -0.49 -8.95 -0.44 2.25e-17 Atrioventricular conduction; LIHC cis rs9916302 0.706 rs4795385 chr17:37733148 A/G cg07936489 chr17:37558343 FBXL20 0.84 12.11 0.55 2.51e-28 Glomerular filtration rate (creatinine); LIHC cis rs477692 0.789 rs568166 chr10:131400088 G/A cg19680672 chr10:131412579 MGMT -0.45 -6.94 -0.35 2.02e-11 Response to temozolomide; LIHC cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC trans rs4819388 0.915 rs6518352 chr21:45646698 A/G cg17383793 chr5:52405638 MOCS2 0.4 6.05 0.31 3.88e-9 Celiac disease; LIHC cis rs769267 0.965 rs10419245 chr19:19383755 G/A cg03709012 chr19:19516395 GATAD2A 0.93 15.2 0.63 3.22e-40 Tonsillectomy; LIHC cis rs904251 0.828 rs1757174 chr6:37486695 G/A cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.39e-12 Cognitive performance; LIHC trans rs2018683 0.834 rs2012754 chr7:29026257 G/A cg19402173 chr7:128379420 CALU -0.39 -6.27 -0.32 1.08e-9 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs611744 0.967 rs569701 chr8:109239207 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs7647973 0.961 rs4955417 chr3:49298205 T/C cg07636037 chr3:49044803 WDR6 0.5 6.24 0.32 1.3e-9 Menarche (age at onset); LIHC cis rs1144333 0.737 rs1144331 chr1:76272357 G/A cg22875332 chr1:76189707 ACADM -0.43 -6.91 -0.35 2.45e-11 Attention function in attention deficit hyperactive disorder; LIHC trans rs2727020 0.894 rs3862342 chr11:49357043 C/T cg18944383 chr4:111397179 ENPEP 0.28 6.42 0.33 4.47e-10 Coronary artery disease; LIHC cis rs77637988 0.631 rs7573316 chr2:48600692 C/T cg15846641 chr2:48541264 FOXN2 0.59 8.0 0.4 1.97e-14 Joint mobility (Beighton score); LIHC cis rs727505 1.000 rs10230610 chr7:124425398 A/C cg23710748 chr7:124431027 NA -0.35 -6.04 -0.31 4.04e-9 Lewy body disease; LIHC cis rs9303401 0.921 rs34102441 chr17:56877414 A/G cg12560992 chr17:57184187 TRIM37 0.74 10.96 0.51 3.56e-24 Cognitive test performance; LIHC cis rs8067354 0.645 rs2645491 chr17:57877049 C/T cg02344993 chr17:57696989 CLTC 0.69 11.63 0.53 1.44e-26 Hemoglobin concentration; LIHC cis rs924607 1.000 rs1697978 chr5:642829 A/G cg04221910 chr5:616842 CEP72 0.41 7.33 0.37 1.68e-12 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs60871478 0.947 rs62432239 chr7:794576 C/T cg27478167 chr7:817139 HEATR2 -0.41 -5.83 -0.3 1.26e-8 Cerebrospinal P-tau181p levels; LIHC cis rs7511006 0.893 rs760743 chr22:50647375 C/T cg07895657 chr22:50616420 PANX2 -0.39 -6.74 -0.34 6.65e-11 Obesity-related traits; LIHC trans rs1814175 0.817 rs4881648 chr11:49812901 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3e-11 Height; LIHC cis rs9611565 0.559 rs132765 chr22:42008068 A/G cg03806693 chr22:41940476 POLR3H 0.98 10.67 0.5 4.01e-23 Vitiligo; LIHC cis rs7100689 0.784 rs7078075 chr10:82162768 A/G cg01528321 chr10:82214614 TSPAN14 0.92 13.5 0.59 1.32e-33 Post bronchodilator FEV1; LIHC cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg22105103 chr4:187893119 NA 0.35 8.63 0.42 2.4e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs2274273 0.967 rs2094102 chr14:55591098 T/C cg01864836 chr14:55583639 NA -0.36 -6.58 -0.34 1.73e-10 Protein biomarker; LIHC cis rs17106184 1.000 rs72898921 chr1:50928775 C/T cg07174182 chr1:51127561 FAF1 -0.6 -6.7 -0.34 8.43e-11 Type 2 diabetes; LIHC cis rs9430161 0.579 rs9659356 chr1:11034817 A/G cg02454025 chr1:11042201 C1orf127 0.98 19.41 0.72 4.17e-57 Ewing sarcoma; LIHC cis rs4595586 0.545 rs58154430 chr12:39386649 C/T cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg17554472 chr22:41940697 POLR3H 0.58 6.32 0.32 8.02e-10 Vitiligo; LIHC cis rs1670533 1.000 rs6836350 chr4:1069973 C/T cg27284194 chr4:1044797 NA 0.6 8.92 0.43 2.84e-17 Recombination rate (females); LIHC cis rs6088590 1.000 rs11698977 chr20:33449691 C/T cg06115741 chr20:33292138 TP53INP2 0.58 7.91 0.39 3.71e-14 Coronary artery disease; LIHC cis rs752010 0.714 rs10789403 chr1:42085869 G/A cg06885757 chr1:42089581 HIVEP3 0.32 6.7 0.34 8.6e-11 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.69 -0.34 9.38e-11 Total body bone mineral density; LIHC trans rs3960554 0.808 rs11983987 chr7:75657850 A/G cg19862616 chr7:65841803 NCRNA00174 0.57 7.8 0.39 7.48e-14 Eotaxin levels; LIHC cis rs9560113 0.573 rs9560132 chr13:112237456 C/T cg10483660 chr13:112241077 NA 0.25 6.4 0.33 5.04e-10 Menarche (age at onset); LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg06873352 chr17:61820015 STRADA 0.72 13.05 0.58 7.43e-32 Prudent dietary pattern; LIHC cis rs7959452 0.640 rs4274230 chr12:69700772 T/G cg14784868 chr12:69753453 YEATS4 0.88 17.07 0.68 1.12e-47 Blood protein levels; LIHC cis rs1190552 0.761 rs12896625 chr14:102838957 T/C cg10241871 chr14:102965420 TECPR2 0.39 5.78 0.3 1.66e-8 Blood protein levels; LIHC cis rs17854409 0.764 rs12625513 chr20:61475661 G/A cg06598544 chr20:61472147 COL9A3 -0.9 -7.65 -0.38 2.11e-13 Obesity-related traits; LIHC trans rs3858145 0.588 rs736535 chr10:70043916 G/A cg04882175 chr6:131122610 NA -0.51 -6.14 -0.32 2.31e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs17253792 0.822 rs10148983 chr14:56051879 A/G cg01858014 chr14:56050164 KTN1 -0.76 -8.12 -0.4 8.33e-15 Putamen volume; LIHC cis rs747782 0.646 rs4752839 chr11:47495202 G/A cg20307385 chr11:47447363 PSMC3 -0.56 -6.35 -0.32 6.7e-10 Intraocular pressure; LIHC trans rs11088226 0.681 rs2409456 chr21:33929374 G/A cg09050820 chr6:167586206 TCP10L2 0.85 13.46 0.59 1.88e-33 Gastritis; LIHC cis rs950169 0.614 rs765524 chr15:84681782 G/T cg17507749 chr15:85114479 UBE2QP1 0.69 6.75 0.34 6.46e-11 Schizophrenia; LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.68 0.8 5.83e-78 Prudent dietary pattern; LIHC cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg17971929 chr21:40555470 PSMG1 0.85 10.22 0.48 1.42e-21 Cognitive function; LIHC cis rs7116495 0.609 rs12275171 chr11:71835373 C/T cg10381502 chr11:71823885 C11orf51 1.06 9.3 0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs9503598 0.778 rs10155771 chr6:3465930 G/A cg00476032 chr6:3446245 SLC22A23 0.44 8.37 0.41 1.46e-15 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs9902453 0.845 rs12602426 chr17:28158815 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.98 0.54 7.79e-28 Coffee consumption (cups per day); LIHC cis rs367615 0.918 rs10067984 chr5:108872684 C/T cg17395555 chr5:108820864 NA 0.34 7.02 0.35 1.23e-11 Colorectal cancer (SNP x SNP interaction); LIHC cis rs4253772 0.591 rs6007747 chr22:46657261 A/G cg24881330 chr22:46731750 TRMU 0.54 5.82 0.3 1.39e-8 LDL cholesterol;Cholesterol, total; LIHC cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg24209194 chr3:40518798 ZNF619 0.45 6.46 0.33 3.66e-10 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18779695 chr6:36164024 BRPF3 0.43 6.07 0.31 3.38e-9 Pancreatic cancer; LIHC cis rs9457247 0.967 rs1794696 chr6:167396174 T/C cg07741184 chr6:167504864 NA 0.31 7.03 0.36 1.1e-11 Crohn's disease; LIHC trans rs10411161 0.580 rs10409620 chr19:52371176 A/G cg22319618 chr22:45562946 NUP50 -0.51 -7.39 -0.37 1.17e-12 Breast cancer; LIHC cis rs9914988 0.887 rs28873200 chr17:27149512 A/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7615952 0.673 rs3811677 chr3:125648080 G/A cg05084668 chr3:125655381 ALG1L -0.6 -8.67 -0.42 1.8e-16 Blood pressure (smoking interaction); LIHC cis rs6456156 0.792 rs4710181 chr6:167513998 T/C cg07741184 chr6:167504864 NA 0.28 6.82 0.35 4.24e-11 Primary biliary cholangitis; LIHC cis rs1639906 0.895 rs62443039 chr7:2209354 C/T cg22963979 chr7:1858916 MAD1L1 0.4 5.74 0.3 2.12e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs12887734 0.546 rs4906376 chr14:104272165 A/C cg01849466 chr14:104193079 ZFYVE21 -0.39 -5.83 -0.3 1.31e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2404618 0.593 rs7815979 chr8:1484887 A/G cg22787604 chr8:1509810 DLGAP2 -0.36 -6.3 -0.32 9.23e-10 Lung cancer; LIHC cis rs55882075 0.583 rs9637934 chr5:179114025 G/C cg14593053 chr5:179126677 CANX 0.41 7.07 0.36 8.86e-12 Monocyte percentage of white cells; LIHC cis rs11676348 0.783 rs13035513 chr2:218960680 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.44 -5.97 -0.31 5.81e-9 Ulcerative colitis; LIHC cis rs6665290 0.835 rs11578479 chr1:227210888 A/T cg10327440 chr1:227177885 CDC42BPA -1.12 -22.19 -0.77 3.15e-68 Myeloid white cell count; LIHC trans rs1814175 0.645 rs10839382 chr11:49823172 C/T cg03929089 chr4:120376271 NA -0.84 -15.95 -0.65 3.17e-43 Height; LIHC cis rs6089584 1.000 rs3787424 chr20:60559219 G/A cg06108461 chr20:60628389 TAF4 -0.89 -13.87 -0.6 4.92e-35 Body mass index; LIHC cis rs7772486 0.754 rs702319 chr6:146006117 T/C cg23711669 chr6:146136114 FBXO30 -0.7 -11.52 -0.53 3.71e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs561341 0.681 rs56064462 chr17:30235116 G/A cg13647721 chr17:30228624 UTP6 0.73 8.08 0.4 1.13e-14 Hip circumference adjusted for BMI; LIHC cis rs644799 0.710 rs11021309 chr11:95501898 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 12.04 0.55 4.52e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs921968 0.509 rs556468 chr2:219355794 G/A cg02985541 chr2:219472218 PLCD4 0.43 6.95 0.35 1.84e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs11719291 0.504 rs34571182 chr3:49209057 T/A cg00383909 chr3:49044727 WDR6 0.88 7.4 0.37 1.04e-12 Cognitive function; LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs1348850 0.837 rs4243388 chr2:178284604 T/G cg27490568 chr2:178487706 NA 0.36 5.72 0.3 2.31e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9427116 0.840 rs9427114 chr1:154626705 T/C cg17218026 chr1:154582156 ADAR 0.3 5.9 0.3 8.88e-9 Blood protein levels; LIHC cis rs35110281 0.574 rs1836856 chr21:44964638 A/T cg21573476 chr21:45109991 RRP1B -0.5 -9.27 -0.45 2.15e-18 Mean corpuscular volume; LIHC cis rs568617 1.000 rs694994 chr11:65653309 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.44 6.45 0.33 3.78e-10 Crohn's disease; LIHC cis rs12765878 0.967 rs10883948 chr10:105667552 G/T cg11005552 chr10:105648138 OBFC1 0.38 6.09 0.31 3.03e-9 Coronary artery disease; LIHC cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg27297192 chr10:134578999 INPP5A 0.55 7.59 0.38 3.1400000000000003e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12497850 0.931 rs9840684 chr3:48893780 T/C cg07636037 chr3:49044803 WDR6 0.93 16.69 0.67 3.76e-46 Parkinson's disease; LIHC cis rs4407350 0.756 rs131168 chr22:44896225 T/C cg26276947 chr22:44892394 LDOC1L 0.34 6.63 0.34 1.34e-10 Intelligence (multi-trait analysis); LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg11381792 chr21:45432451 TRAPPC10 -0.45 -6.07 -0.31 3.45e-9 Triglycerides; LIHC cis rs10870270 1.000 rs6560694 chr10:133773448 G/A cg08754478 chr10:133766260 PPP2R2D -0.54 -7.94 -0.39 2.94e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs8067354 0.645 rs2665403 chr17:57889985 G/A cg02344993 chr17:57696989 CLTC 0.73 12.38 0.56 2.54e-29 Hemoglobin concentration; LIHC cis rs8114671 0.562 rs6088621 chr20:33418740 C/T cg07148914 chr20:33460835 GGT7 0.59 8.58 0.42 3.45e-16 Height; LIHC cis rs7937682 0.889 rs1784785 chr11:111483306 A/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.96 -0.51 3.76e-24 Primary sclerosing cholangitis; LIHC cis rs10871290 0.881 rs11649338 chr16:74471420 C/T cg01733217 chr16:74700730 RFWD3 -0.4 -6.92 -0.35 2.23e-11 Breast cancer; LIHC cis rs600806 0.821 rs1030522 chr1:109900707 C/G cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.27e-13 Intelligence (multi-trait analysis); LIHC cis rs36051895 0.587 rs7036761 chr9:5198781 A/C cg02405213 chr9:5042618 JAK2 0.68 10.86 0.51 8.24e-24 Pediatric autoimmune diseases; LIHC cis rs2073499 0.935 rs57842657 chr3:50227787 T/A cg03645007 chr3:50255295 SLC38A3 0.47 6.25 0.32 1.22e-9 Schizophrenia; LIHC cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg18404041 chr3:52824283 ITIH1 -0.66 -10.81 -0.5 1.31e-23 Bipolar disorder; LIHC trans rs9914544 1.000 rs9916245 chr17:18766825 C/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.22 -0.32 1.42e-9 Educational attainment (years of education); LIHC cis rs875971 0.862 rs1643375 chr7:65872677 T/C cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs9517302 0.615 rs9517306 chr13:99097962 T/C cg24044564 chr13:99115944 STK24 0.48 6.88 0.35 2.84e-11 Obesity-related traits; LIHC cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC trans rs7618501 0.538 rs9856572 chr3:50109073 A/T cg21659725 chr3:3221576 CRBN -0.66 -10.57 -0.5 8.58e-23 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs2808584 chr1:231512925 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs6542838 0.553 rs6739503 chr2:99537295 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.5 -7.08 -0.36 8.12e-12 Fear of minor pain; LIHC cis rs589448 0.902 rs315124 chr12:69771727 G/A cg22834771 chr12:69754056 YEATS4 -0.54 -9.87 -0.47 2.23e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs1577917 1.000 rs1911553 chr6:86630892 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC cis rs11690935 0.959 rs6754817 chr2:172663394 C/T cg13550731 chr2:172543902 DYNC1I2 -0.91 -16.76 -0.67 1.97e-46 Schizophrenia; LIHC cis rs7107174 1.000 rs1942352 chr11:77970563 T/G cg02023728 chr11:77925099 USP35 0.5 9.71 0.47 7.35e-20 Testicular germ cell tumor; LIHC cis rs4865169 0.783 rs7668814 chr4:57825190 A/G cg25525207 chr4:57843836 C4orf14;POLR2B -0.37 -5.76 -0.3 1.84e-8 Breast cancer; LIHC cis rs9910055 0.530 rs7222349 chr17:42304644 C/T cg19774624 chr17:42201019 HDAC5 -0.56 -7.87 -0.39 4.62e-14 Total body bone mineral density; LIHC cis rs7772486 0.790 rs7753696 chr6:146279098 G/T cg23711669 chr6:146136114 FBXO30 -0.7 -12.15 -0.55 1.72e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs11792861 0.926 rs72607166 chr9:111821530 A/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.6 -0.34 1.55e-10 Menarche (age at onset); LIHC cis rs11764590 0.724 rs55669426 chr7:2090129 G/C cg23043544 chr7:2124092 MAD1L1 -0.4 -6.52 -0.33 2.49e-10 Neuroticism; LIHC cis rs9911578 1.000 rs12453049 chr17:56611372 C/T cg12560992 chr17:57184187 TRIM37 -0.98 -17.72 -0.69 2.56e-50 Intelligence (multi-trait analysis); LIHC cis rs10193935 1.000 rs12612527 chr2:42392099 T/C cg27598129 chr2:42591480 NA -0.75 -11.23 -0.52 3.97e-25 Colonoscopy-negative controls vs population controls; LIHC trans rs17685 0.712 rs10235738 chr7:75773460 G/A cg19862616 chr7:65841803 NCRNA00174 0.78 14.69 0.62 3.25e-38 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2576037 0.583 rs545344 chr18:44367079 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 9.77 0.47 4.85e-20 Personality dimensions; LIHC cis rs2832191 1.000 rs2832184 chr21:30483265 C/T cg24692254 chr21:30365293 RNF160 -0.63 -11.24 -0.52 3.79e-25 Dental caries; LIHC trans rs35110281 0.837 rs7279968 chr21:45077398 C/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.44 6.18 0.32 1.83e-9 Mean corpuscular volume; LIHC cis rs8067545 0.611 rs2703800 chr17:20086562 C/T cg13482628 chr17:19912719 NA 0.43 7.09 0.36 7.79e-12 Schizophrenia; LIHC cis rs2404602 0.716 rs1874944 chr15:76863928 A/G cg03037974 chr15:76606532 NA 0.74 14.47 0.62 2.32e-37 Blood metabolite levels; LIHC cis rs6545883 0.859 rs2600661 chr2:61543081 T/C cg14146966 chr2:61757674 XPO1 -0.43 -7.33 -0.37 1.7e-12 Tuberculosis; LIHC cis rs12022452 0.556 rs12037288 chr1:40996297 G/A cg25568243 chr1:40974465 DEM1 0.45 5.9 0.3 8.79e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs4906332 1.000 rs3783397 chr14:103947289 A/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.28 -0.32 1.04e-9 Coronary artery disease; LIHC cis rs9517320 0.534 rs9554478 chr13:99187792 G/A cg07423050 chr13:99094983 FARP1 -0.51 -8.94 -0.44 2.52e-17 Longevity; LIHC cis rs8180040 0.764 rs11716539 chr3:47186503 G/T cg16586182 chr3:47516702 SCAP -0.51 -9.25 -0.45 2.44e-18 Colorectal cancer; LIHC cis rs6570726 0.905 rs375692 chr6:145840368 A/G cg23711669 chr6:146136114 FBXO30 0.54 9.74 0.47 5.84e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2760061 0.717 rs708117 chr1:228199902 G/A cg01200585 chr1:228362443 C1orf69 0.39 6.05 0.31 3.76e-9 Diastolic blood pressure; LIHC cis rs12478296 1.000 rs55814222 chr2:243041166 C/T cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.1e-27 Obesity-related traits; LIHC cis rs765787 0.530 rs11858988 chr15:45522114 T/C cg24006582 chr15:45444508 DUOX1 -0.5 -7.26 -0.37 2.56e-12 Uric acid levels; LIHC cis rs55665837 1.000 rs10047429 chr11:14439032 C/T cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs1577917 0.958 rs12207374 chr6:86656645 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.93 -0.35 2.09e-11 Response to antipsychotic treatment; LIHC cis rs7249142 0.549 rs7260127 chr19:19280499 C/T cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B 0.41 6.94 0.35 1.96e-11 IgG glycosylation; LIHC cis rs9633740 1.000 rs7900536 chr10:82253701 G/T cg01528321 chr10:82214614 TSPAN14 0.92 11.9 0.54 1.49e-27 Post bronchodilator FEV1; LIHC cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg26818010 chr10:134567672 INPP5A -0.71 -9.04 -0.44 1.2e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8060686 0.516 rs13339471 chr16:68253008 A/G cg05110241 chr16:68378359 PRMT7 -0.51 -6.09 -0.31 3.12e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs614226 0.935 rs3887875 chr12:120895749 A/G cg01236616 chr12:121019343 POP5 -1.19 -18.27 -0.7 1.62e-52 Type 1 diabetes nephropathy; LIHC cis rs765787 0.530 rs2554456 chr15:45521138 A/C cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.7e-10 Uric acid levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22517316 chr8:42128500 IKBKB 0.47 6.04 0.31 4.02e-9 Lung function (FEV1/FVC); LIHC cis rs7116495 0.867 rs1612492 chr11:71583865 T/G cg26138937 chr11:71823887 C11orf51 0.68 6.53 0.33 2.4e-10 Severe influenza A (H1N1) infection; LIHC trans rs9858542 0.953 rs9827708 chr3:49649989 C/G cg21659725 chr3:3221576 CRBN -0.54 -6.1 -0.31 2.91e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2991971 0.967 rs11211130 chr1:45986852 G/C cg15605315 chr1:45957053 TESK2 0.49 6.65 0.34 1.15e-10 High light scatter reticulocyte count; LIHC trans rs1555543 0.517 rs2391766 chr1:96909240 T/C cg10631902 chr5:14652156 NA -0.32 -6.59 -0.34 1.64e-10 Body mass index; LIHC cis rs763014 1.000 rs2269558 chr16:682250 C/T cg00802000 chr16:706648 WDR90 -0.38 -6.2 -0.32 1.62e-9 Height; LIHC cis rs7586673 0.866 rs7579662 chr2:161915810 G/A cg22496339 chr2:162101262 NA 0.66 9.93 0.47 1.37e-20 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.752 rs11211168 chr1:46163647 C/T cg03146154 chr1:46216737 IPP 0.58 9.47 0.46 4.65e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6448317 0.906 rs6448313 chr4:24905088 G/A cg21108841 chr4:24914750 CCDC149 0.57 8.3 0.41 2.47e-15 Heschl's gyrus morphology; LIHC cis rs17685 0.712 rs7778735 chr7:75770237 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9399135 0.967 rs9389251 chr6:135325717 A/G cg24558204 chr6:135376177 HBS1L 0.4 6.67 0.34 1.04e-10 Red blood cell count; LIHC cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg08888203 chr3:10149979 C3orf24 0.56 6.45 0.33 3.89e-10 Alzheimer's disease; LIHC cis rs992157 0.798 rs4996257 chr2:219162836 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.79 12.76 0.57 9.36e-31 Colorectal cancer; LIHC cis rs2304456 1.000 rs5030044 chr3:186449122 A/G cg12454167 chr3:186435060 KNG1 0.34 6.06 0.31 3.61e-9 Blood protein levels; LIHC cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg11890956 chr21:40555474 PSMG1 1.04 14.97 0.63 2.54e-39 Cognitive function; LIHC cis rs10847980 0.590 rs77970074 chr12:123292186 T/G cg07706471 chr12:123319906 HIP1R 0.75 8.19 0.4 5.21e-15 Adiponectin levels; LIHC cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg05896524 chr21:47604654 C21orf56 0.5 7.99 0.4 2.1e-14 Testicular germ cell tumor; LIHC cis rs7927771 0.524 rs7107792 chr11:47669249 A/C cg20307385 chr11:47447363 PSMC3 0.75 11.31 0.52 2.08e-25 Subjective well-being; LIHC cis rs2075371 0.637 rs2544165 chr7:133920443 A/G cg11752832 chr7:134001865 SLC35B4 -0.45 -6.6 -0.34 1.61e-10 Mean platelet volume; LIHC cis rs13161895 0.818 rs116463976 chr5:179484519 G/C cg06664874 chr5:179499304 RNF130 0.67 7.7 0.38 1.51e-13 LDL cholesterol; LIHC cis rs7312933 0.531 rs1796380 chr12:42791543 T/G cg17420585 chr12:42539391 GXYLT1 0.35 5.71 0.3 2.39e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10489202 0.608 rs16828093 chr1:168078384 C/T cg24449463 chr1:168025552 DCAF6 -0.53 -8.1 -0.4 9.81e-15 Schizophrenia; LIHC cis rs921968 0.565 rs4674329 chr2:219595507 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7618501 0.735 rs9876508 chr3:49780844 G/A cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg26338869 chr17:61819248 STRADA 0.52 7.0 0.35 1.36e-11 Height; LIHC cis rs9399135 0.935 rs949547 chr6:135343499 C/G cg24558204 chr6:135376177 HBS1L 0.42 6.82 0.35 4.14e-11 Red blood cell count; LIHC cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs75920871 0.588 rs1815789 chr11:116834953 T/C cg01368799 chr11:117014884 PAFAH1B2 -0.43 -5.76 -0.3 1.85e-8 Subjective well-being; LIHC cis rs7872515 0.887 rs58129324 chr9:94839105 T/C cg01248375 chr9:94877805 SPTLC1 0.56 8.27 0.41 2.99e-15 Bipolar disorder and schizophrenia; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.57 0.46 2.19e-19 Height; LIHC cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.15 -0.44 5.28e-18 Bipolar disorder; LIHC cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7224685 0.906 rs2278524 chr17:4081975 A/G cg11204139 chr17:3907470 NA -0.57 -8.36 -0.41 1.6e-15 Type 2 diabetes; LIHC cis rs965469 0.779 rs2236103 chr20:3276821 A/G cg25506879 chr20:3388711 C20orf194 0.5 6.21 0.32 1.55e-9 IFN-related cytopenia; LIHC cis rs3796619 1.000 rs11247973 chr4:1094314 G/A cg27284194 chr4:1044797 NA 0.64 10.56 0.5 9.32e-23 Recombination rate (males); LIHC cis rs1707322 1.000 rs11211219 chr1:46359478 G/C cg03146154 chr1:46216737 IPP 0.47 7.72 0.39 1.3e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1941023 0.584 rs2014121 chr11:60156297 T/C cg08716584 chr11:60157161 MS4A7 -0.36 -8.26 -0.41 3.34e-15 Congenital heart disease (maternal effect); LIHC trans rs10506458 1.000 rs10506458 chr12:63445092 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.42 -0.49 2.92e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs9517320 1.000 rs7994160 chr13:99132749 C/A cg07423050 chr13:99094983 FARP1 0.35 5.78 0.3 1.65e-8 Longevity; LIHC cis rs2637266 0.749 rs4979830 chr10:78457484 C/T cg18941641 chr10:78392320 NA 0.28 6.0 0.31 5.14e-9 Pulmonary function; LIHC cis rs9911578 0.902 rs12948746 chr17:57071892 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.94 0.7 3.47e-51 Intelligence (multi-trait analysis); LIHC cis rs2901460 0.509 rs6750080 chr2:62071542 C/T cg02183531 chr2:62113199 CCT4 -0.41 -6.13 -0.31 2.42e-9 Mean corpuscular volume; LIHC cis rs7412746 0.571 rs12402939 chr1:150615094 A/C cg17724175 chr1:150552817 MCL1 0.51 10.2 0.48 1.61e-21 Melanoma; LIHC cis rs2180341 1.000 rs3798850 chr6:127613966 C/T cg24812749 chr6:127587940 RNF146 1.07 16.08 0.66 9.77e-44 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25118631 chr4:120206103 USP53 -0.39 -6.93 -0.35 2.11e-11 Cognitive function; LIHC cis rs10911232 0.524 rs10911209 chr1:183013988 T/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.01e-22 Hypertriglyceridemia; LIHC cis rs912330 0.500 rs9556967 chr13:99186751 G/T cg07423050 chr13:99094983 FARP1 -0.33 -6.05 -0.31 3.83e-9 Alzheimer's disease; LIHC cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.09 -0.36 7.75e-12 Bipolar disorder; LIHC cis rs903552 1.000 rs12908079 chr15:102003820 C/A cg25677261 chr15:102009856 PCSK6 -0.45 -6.36 -0.33 6.57e-10 Diabetic kidney disease; LIHC cis rs7786877 0.723 rs62482237 chr7:100213476 A/G cg00334542 chr7:100209784 MOSPD3 -0.69 -6.52 -0.33 2.57e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1144333 0.655 rs17097695 chr1:76387258 A/C cg03433033 chr1:76189801 ACADM 0.53 7.45 0.37 7.73e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs12478296 0.901 rs9653611 chr2:243006956 C/G cg06360820 chr2:242988706 NA -0.82 -12.21 -0.55 1.01e-28 Obesity-related traits; LIHC cis rs9303401 0.614 rs3887355 chr17:56538639 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.92 12.58 0.56 4.44e-30 Cognitive test performance; LIHC cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg26531700 chr6:26746687 NA 0.39 6.5 0.33 2.92e-10 Intelligence (multi-trait analysis); LIHC cis rs72627123 0.867 rs77320708 chr14:74478482 T/C cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.95 0.31 6.57e-9 Morning vs. evening chronotype; LIHC cis rs2153535 0.580 rs2327062 chr6:8453858 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.24 0.55 8.47e-29 Motion sickness; LIHC cis rs826838 0.967 rs7970069 chr12:38810631 T/C cg26384229 chr12:38710491 ALG10B 1.06 14.27 0.61 1.46e-36 Heart rate; LIHC cis rs763121 0.752 rs6001190 chr22:39073811 T/C cg14440974 chr22:39074834 NA -0.44 -7.19 -0.36 4.21e-12 Menopause (age at onset); LIHC cis rs11608355 0.515 rs4766609 chr12:109973297 A/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs2204008 0.537 rs28680519 chr12:38502946 C/T cg26384229 chr12:38710491 ALG10B 0.9 11.49 0.53 4.75e-26 Bladder cancer; LIHC cis rs12549902 0.966 rs4737000 chr8:41509727 A/C cg17182837 chr8:41585554 ANK1 -0.23 -5.83 -0.3 1.3e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs12602486 1.000 rs16940539 chr17:42224581 C/G cg13607699 chr17:42295918 UBTF -0.74 -6.35 -0.32 6.99e-10 Glycated hemoglobin levels; LIHC cis rs34172651 0.687 rs8044992 chr16:24811207 T/C cg04756594 chr16:24857601 SLC5A11 0.45 7.16 0.36 4.94e-12 Intelligence (multi-trait analysis); LIHC cis rs523522 0.926 rs10774555 chr12:120971978 G/A cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs57590327 0.508 rs13093082 chr3:81949958 C/T cg07356753 chr3:81810745 GBE1 -0.54 -8.41 -0.41 1.13e-15 Extraversion; LIHC cis rs9790314 0.750 rs6765270 chr3:160899974 A/G cg03342759 chr3:160939853 NMD3 -0.78 -10.75 -0.5 2.03e-23 Morning vs. evening chronotype; LIHC cis rs881375 0.702 rs3761847 chr9:123690239 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 6.03 0.31 4.3e-9 Rheumatoid arthritis; LIHC cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.79 0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs738322 1.000 rs4381 chr22:38570791 T/C cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs57502260 0.704 rs923346 chr11:68182375 T/C cg16797656 chr11:68205561 LRP5 0.59 7.83 0.39 6.36e-14 Total body bone mineral density (age 45-60); LIHC cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg03264133 chr6:25882463 NA 0.88 12.22 0.55 9.76e-29 Blood metabolite levels; LIHC cis rs7572733 0.555 rs2164071 chr2:198915467 T/C cg03934865 chr2:198174659 NA 0.42 5.93 0.31 7.6e-9 Dermatomyositis; LIHC cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg07061783 chr6:25882402 NA -0.67 -9.12 -0.44 6.42e-18 Blood metabolite levels; LIHC cis rs9640161 0.789 rs10282458 chr7:150045302 C/T cg27494647 chr7:150038898 RARRES2 0.37 7.0 0.35 1.32e-11 Blood protein levels;Circulating chemerin levels; LIHC trans rs8117834 0.574 rs6118061 chr20:8087343 T/C cg00593689 chr4:53575888 NA 0.41 6.84 0.35 3.77e-11 Chronic kidney disease; LIHC cis rs875971 0.862 rs6955837 chr7:66043142 C/T cg18252515 chr7:66147081 NA 0.45 6.57 0.33 1.83e-10 Aortic root size; LIHC cis rs7044106 0.762 rs1886337 chr9:123443776 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.67 0.5 4.05e-23 Hip circumference adjusted for BMI; LIHC cis rs4474465 1.000 rs7927722 chr11:78210893 T/C cg02023728 chr11:77925099 USP35 -0.35 -5.97 -0.31 6e-9 Alzheimer's disease (survival time); LIHC cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg03517284 chr6:25882590 NA -0.59 -7.05 -0.36 1.02e-11 Intelligence (multi-trait analysis); LIHC cis rs6456156 0.766 rs150112 chr6:167509878 C/T cg12798992 chr6:167411361 FGFR1OP -0.37 -5.94 -0.31 7.08e-9 Primary biliary cholangitis; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg20470467 chr16:30886130 NA 0.39 6.16 0.32 2.07e-9 Morning vs. evening chronotype; LIHC cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg13271783 chr10:134563150 INPP5A -0.54 -6.93 -0.35 2.07e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg07092213 chr7:1199455 ZFAND2A -0.44 -6.3 -0.32 9.01e-10 Longevity;Endometriosis; LIHC cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg15691649 chr6:25882328 NA -0.37 -5.86 -0.3 1.07e-8 Height; LIHC cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg22029157 chr1:209979665 IRF6 0.51 8.3 0.41 2.49e-15 Cleft lip with or without cleft palate; LIHC cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -11.92 -0.54 1.19e-27 Alzheimer's disease; LIHC cis rs769267 0.899 rs67720221 chr19:19440864 C/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.06 -0.31 3.53e-9 Tonsillectomy; LIHC cis rs7818688 0.614 rs12056808 chr8:95876868 G/A cg16049864 chr8:95962084 TP53INP1 0.51 5.83 0.3 1.27e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4631830 0.720 rs2611512 chr10:51515534 A/G cg16070123 chr10:51489643 NA -0.37 -5.92 -0.3 7.9e-9 Prostate-specific antigen levels; LIHC trans rs9914544 0.564 rs9907723 chr17:18758853 T/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.59 -0.34 1.68e-10 Educational attainment (years of education); LIHC cis rs28647808 0.881 rs7042326 chr9:136266636 T/C cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs2115630 1.000 rs10220733 chr15:85280864 G/A cg12501888 chr15:85177176 SCAND2 -0.5 -7.79 -0.39 7.99e-14 P wave terminal force; LIHC trans rs4566357 0.615 rs2272200 chr2:227912331 G/A cg16088116 chr21:44841560 SIK1 -0.4 -6.23 -0.32 1.4e-9 Coronary artery disease; LIHC cis rs7208859 0.623 rs11652533 chr17:29060601 A/C cg14067834 chr17:29058358 SUZ12P 0.68 6.79 0.34 5.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11122272 0.766 rs2790872 chr1:231540543 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.64 -10.21 -0.48 1.51e-21 Hemoglobin concentration; LIHC cis rs2404602 0.740 rs34924128 chr15:76965169 T/G cg03037974 chr15:76606532 NA 0.74 14.52 0.62 1.54e-37 Blood metabolite levels; LIHC cis rs2710642 0.611 rs6752010 chr2:62859042 C/T cg17519650 chr2:63277830 OTX1 -0.47 -6.91 -0.35 2.38e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1707322 1.000 rs4660332 chr1:46461418 T/A cg03146154 chr1:46216737 IPP 0.47 7.56 0.38 3.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6840360 0.571 rs6833814 chr4:152539679 A/G cg22705602 chr4:152727874 NA -0.33 -6.41 -0.33 4.78e-10 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs9979545 chr21:46679805 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.65 0.53 1.2e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7772486 0.875 rs2777481 chr6:146310036 G/T cg23711669 chr6:146136114 FBXO30 0.59 10.21 0.48 1.6e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs7617773 0.780 rs13067450 chr3:48337206 C/T cg11946769 chr3:48343235 NME6 0.92 11.62 0.53 1.58e-26 Coronary artery disease; LIHC cis rs7582720 1.000 rs72936348 chr2:204064839 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.76 6.13 0.31 2.36e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9814567 0.806 rs9824185 chr3:134324024 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.4 -0.45 7.89e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7615952 0.512 rs34085484 chr3:125544186 T/C cg05084668 chr3:125655381 ALG1L -0.34 -6.13 -0.31 2.39e-9 Blood pressure (smoking interaction); LIHC trans rs1814175 0.791 rs1722011 chr11:49899340 G/C cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs12586317 0.547 rs10142667 chr14:35445090 A/G cg16230307 chr14:35515116 FAM177A1 0.77 12.75 0.57 9.66e-31 Psoriasis; LIHC cis rs400736 0.729 rs2493215 chr1:8007716 C/T cg25007680 chr1:8021821 PARK7 0.46 7.28 0.37 2.27e-12 Response to antidepressants and depression; LIHC cis rs8067354 0.574 rs2526353 chr17:57988607 G/T cg13753209 chr17:57696993 CLTC 0.71 10.57 0.5 8.45e-23 Hemoglobin concentration; LIHC cis rs10876993 0.890 rs1678516 chr12:58047458 G/A cg18357645 chr12:58087776 OS9 0.5 8.05 0.4 1.38e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs4699052 0.963 rs7672802 chr4:104212233 A/T cg16532752 chr4:104119610 CENPE -0.39 -6.29 -0.32 9.82e-10 Testicular germ cell tumor; LIHC cis rs7570971 0.617 rs1869829 chr2:135877562 C/T cg07169764 chr2:136633963 MCM6 -0.52 -7.04 -0.36 1.08e-11 Blood metabolite levels;Body mass index;Cholesterol, total; LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg09455208 chr3:40491958 NA 0.39 7.92 0.39 3.4e-14 Renal cell carcinoma; LIHC cis rs2625529 0.824 rs4411469 chr15:72421689 A/G cg16672083 chr15:72433130 SENP8 -0.31 -5.8 -0.3 1.51e-8 Red blood cell count; LIHC cis rs644799 0.509 rs580181 chr11:95643040 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.61 9.49 0.46 4.06e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs965469 1.000 rs6139103 chr20:3361140 T/C cg25506879 chr20:3388711 C20orf194 -0.57 -6.7 -0.34 8.46e-11 IFN-related cytopenia; LIHC cis rs4888262 0.526 rs8057279 chr16:74627303 C/T cg01733217 chr16:74700730 RFWD3 0.83 16.16 0.66 4.75e-44 Testicular germ cell tumor; LIHC cis rs12893668 0.703 rs34896432 chr14:104027995 C/T cg24130564 chr14:104152367 KLC1 -0.56 -9.28 -0.45 1.97e-18 Reticulocyte count; LIHC cis rs826838 0.935 rs4583043 chr12:38645147 T/G cg26384229 chr12:38710491 ALG10B 1.07 14.54 0.62 1.24e-37 Heart rate; LIHC trans rs66887589 0.720 rs11724758 chr4:120239878 G/A cg25214090 chr10:38739885 LOC399744 0.47 7.75 0.39 1.03e-13 Diastolic blood pressure; LIHC cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg27286337 chr10:134555280 INPP5A 0.92 13.14 0.58 3.26e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2574704 0.886 rs13066755 chr3:11632089 C/T cg15876825 chr3:11651881 VGLL4 -0.46 -7.47 -0.37 6.74e-13 Body mass index; LIHC cis rs2075371 1.000 rs1868783 chr7:133975087 A/G cg20476274 chr7:133979776 SLC35B4 0.76 13.09 0.58 5.08e-32 Mean platelet volume; LIHC cis rs600626 0.529 rs58411334 chr11:75467350 G/T cg24262691 chr11:75473276 NA 0.42 5.93 0.31 7.39e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs6545883 0.965 rs6734830 chr2:61731112 G/A cg15711740 chr2:61764176 XPO1 -0.43 -6.04 -0.31 4.1e-9 Tuberculosis; LIHC cis rs9910055 0.530 rs11656758 chr17:42301541 A/G cg08499158 chr17:42289980 UBTF -0.48 -7.81 -0.39 7.17e-14 Total body bone mineral density; LIHC cis rs12762955 0.561 rs7918118 chr10:1042823 C/A cg26597838 chr10:835615 NA -0.46 -5.81 -0.3 1.45e-8 Response to angiotensin II receptor blocker therapy; LIHC cis rs10170846 0.572 rs12620873 chr2:223419528 A/C cg25565276 chr2:223520875 FARSB 0.77 10.94 0.51 4.46e-24 Schizophrenia (inflammation and infection response interaction); LIHC cis rs7647973 1.000 rs11130190 chr3:49402137 T/C cg07636037 chr3:49044803 WDR6 0.53 6.43 0.33 4.31e-10 Menarche (age at onset); LIHC cis rs2404602 0.583 rs12908334 chr15:76581592 C/T cg03037974 chr15:76606532 NA 0.89 23.03 0.78 1.59e-71 Blood metabolite levels; LIHC cis rs7572733 0.534 rs700684 chr2:198713099 C/T cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs9902453 0.780 rs10445384 chr17:28182685 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 10.58 0.5 8.05e-23 Coffee consumption (cups per day); LIHC cis rs7909074 0.966 rs4245614 chr10:45397007 C/T cg04218760 chr10:45406644 TMEM72 -0.22 -6.79 -0.34 4.99e-11 Mean corpuscular volume; LIHC cis rs6424115 0.618 rs10917420 chr1:24062987 C/T cg15997130 chr1:24165203 NA 0.33 7.01 0.35 1.28e-11 Immature fraction of reticulocytes; LIHC cis rs6722750 0.818 rs12104940 chr2:64385774 A/G cg22352474 chr2:64371530 PELI1 0.46 6.59 0.34 1.67e-10 Neuroticism; LIHC trans rs11098499 1.000 rs35643470 chr4:120184948 T/C cg25214090 chr10:38739885 LOC399744 0.52 7.86 0.39 4.95e-14 Corneal astigmatism; LIHC cis rs7208859 0.673 rs4131618 chr17:29204801 C/T cg13385521 chr17:29058706 SUZ12P 0.84 7.95 0.39 2.79e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs11662586 0.517 rs11663082 chr18:77713494 C/T cg05926928 chr17:57297772 GDPD1 0.47 6.57 0.33 1.86e-10 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs6076065 0.748 rs6048784 chr20:23382652 A/T cg11657817 chr20:23433608 CST11 0.32 6.73 0.34 7.35e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs35110281 0.693 rs2251253 chr21:45092257 T/A cg04455712 chr21:45112962 RRP1B 0.54 9.54 0.46 2.74e-19 Mean corpuscular volume; LIHC cis rs7618915 0.781 rs12489732 chr3:52566820 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.05 0.44 1.08e-17 Bipolar disorder; LIHC cis rs11098499 0.644 rs10050092 chr4:120532085 T/C cg09307838 chr4:120376055 NA 0.67 10.52 0.49 1.27e-22 Corneal astigmatism; LIHC cis rs4474465 0.850 rs10751294 chr11:78253303 T/A cg27205649 chr11:78285834 NARS2 0.4 6.21 0.32 1.58e-9 Alzheimer's disease (survival time); LIHC cis rs116248771 0.739 rs73156426 chr3:158346289 G/A cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.75e-10 diarrhoeal disease at age 2; LIHC cis rs7927771 0.524 rs10769299 chr11:47865160 G/T cg20307385 chr11:47447363 PSMC3 0.72 10.82 0.5 1.19e-23 Subjective well-being; LIHC cis rs56163509 1 rs56163509 chr16:28864471 A/G cg00204512 chr16:28754710 NA 0.36 6.43 0.33 4.28e-10 Tonsillectomy;Mean corpuscular volume; LIHC cis rs4407350 0.756 rs131155 chr22:44891247 A/G cg26276947 chr22:44892394 LDOC1L 0.33 6.39 0.33 5.36e-10 Intelligence (multi-trait analysis); LIHC cis rs6938 0.534 rs7495739 chr15:75185670 C/T cg14664628 chr15:75095509 CSK 0.46 6.6 0.34 1.54e-10 Breast cancer; LIHC cis rs10078 0.515 rs890984 chr5:479540 A/G cg08916839 chr5:415575 AHRR 0.6 12.72 0.57 1.25e-30 Fat distribution (HIV); LIHC cis rs2228479 0.850 rs17226498 chr16:89840631 T/C cg14709524 chr16:89940631 TCF25 0.47 5.85 0.3 1.13e-8 Skin colour saturation; LIHC cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg09222892 chr1:25734099 RHCE 0.45 8.25 0.41 3.54e-15 Erythrocyte sedimentation rate; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16718920 chr1:21113643 HP1BP3 -0.52 -6.84 -0.35 3.59e-11 Systolic blood pressure; LIHC cis rs11098499 0.954 rs12502423 chr4:120424172 A/C cg09307838 chr4:120376055 NA 0.78 12.4 0.56 2.14e-29 Corneal astigmatism; LIHC cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 11.36 0.52 1.36e-25 Platelet count; LIHC cis rs12477438 0.798 rs4850894 chr2:99629396 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -10.77 -0.5 1.69e-23 Chronic sinus infection; LIHC trans rs10242455 0.557 rs57830676 chr7:99281363 C/T cg09045935 chr12:6379348 NA 0.74 6.16 0.32 2.03e-9 Blood metabolite levels; LIHC trans rs1814175 0.817 rs28679516 chr11:50055998 G/A cg03929089 chr4:120376271 NA -0.88 -18.26 -0.7 1.79e-52 Height; LIHC cis rs1577917 0.917 rs4707226 chr6:86527828 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs4319547 1.000 rs7295397 chr12:123116209 C/T cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.54 -0.38 4.14e-13 Body mass index; LIHC cis rs1499614 1.000 rs34250985 chr7:66161062 A/T cg18252515 chr7:66147081 NA -1.34 -15.89 -0.65 5.54e-43 Gout; LIHC cis rs6442522 0.560 rs2305614 chr3:15517318 C/G cg16303742 chr3:15540471 COLQ 0.37 6.04 0.31 4.01e-9 Uric acid levels; LIHC trans rs11098499 0.644 rs3986377 chr4:120260270 G/A cg25214090 chr10:38739885 LOC399744 0.45 7.39 0.37 1.14e-12 Corneal astigmatism; LIHC cis rs72781680 0.611 rs55983206 chr2:24333995 A/C cg06627628 chr2:24431161 ITSN2 -0.65 -7.58 -0.38 3.21e-13 Lymphocyte counts; LIHC cis rs28735056 0.935 rs537962 chr18:77592660 C/G cg20368463 chr18:77673604 PQLC1 0.38 6.66 0.34 1.08e-10 Schizophrenia; LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.72 -0.34 7.76e-11 Bipolar disorder and schizophrenia; LIHC cis rs6684514 1.000 rs12022194 chr1:156312331 T/A cg16558208 chr1:156270281 VHLL 0.55 10.48 0.49 1.84e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs2066819 0.892 rs112931321 chr12:56667894 C/T cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.92e-25 Psoriasis vulgaris; LIHC cis rs11864453 0.616 rs9938025 chr16:72022041 A/G cg01557791 chr16:72042693 DHODH 0.4 6.03 0.31 4.33e-9 Fibrinogen levels; LIHC cis rs7103648 0.864 rs10742802 chr11:47432725 T/G cg20307385 chr11:47447363 PSMC3 1.03 18.02 0.7 1.7e-51 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg22528358 chr1:107598549 PRMT6 0.72 11.91 0.54 1.35e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7772486 0.875 rs6938972 chr6:146410608 G/A cg05347473 chr6:146136440 FBXO30 0.38 5.99 0.31 5.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3820068 0.581 rs72645890 chr1:15930602 A/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs10927875 1.000 rs12138117 chr1:16305279 T/C cg21385522 chr1:16154831 NA -0.88 -11.03 -0.51 2.16e-24 Dilated cardiomyopathy; LIHC cis rs4927850 0.709 rs6783079 chr3:195652708 T/C cg00031303 chr3:195681400 NA 0.55 7.62 0.38 2.53e-13 Pancreatic cancer; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs8067354 0.645 rs72838857 chr17:57836767 A/G cg02344993 chr17:57696989 CLTC 0.71 11.85 0.54 2.25e-27 Hemoglobin concentration; LIHC cis rs6964587 1.000 rs6979085 chr7:91673623 C/T cg17063962 chr7:91808500 NA 1.01 19.45 0.72 2.77e-57 Breast cancer; LIHC cis rs2235642 0.787 rs2235646 chr16:1601287 A/G cg03034668 chr16:1723424 CRAMP1L -0.41 -7.36 -0.37 1.38e-12 Coronary artery disease; LIHC cis rs2075371 1.000 rs432487 chr7:133990114 T/G cg20476274 chr7:133979776 SLC35B4 0.75 12.53 0.56 6.44e-30 Mean platelet volume; LIHC cis rs12702595 0.818 rs10259085 chr7:7268431 C/T cg04827551 chr7:7268805 C1GALT1 0.38 6.86 0.35 3.26e-11 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs2842992 0.830 rs2758313 chr6:160154099 C/G cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.74 0.54 5.78e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs921968 0.643 rs4674305 chr2:219293326 C/T cg02176678 chr2:219576539 TTLL4 0.39 5.81 0.3 1.41e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs6912958 0.781 rs9450738 chr6:88267314 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.7 -0.38 1.44e-13 Monocyte percentage of white cells; LIHC cis rs4676482 0.578 rs784504 chr3:39195260 G/C cg02254461 chr3:39195904 CSRNP1 -0.61 -6.31 -0.32 8.65e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs1348850 0.914 rs4893961 chr2:178411075 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.82 12.62 0.56 3.06e-30 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02400128 chr5:114849010 NA 0.34 6.12 0.31 2.51e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs3806843 0.735 rs2563314 chr5:140047289 A/G cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.6e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs79839061 0.610 rs12651271 chr4:854071 C/T cg07828340 chr4:882639 GAK 0.79 6.83 0.35 3.89e-11 Intelligence (multi-trait analysis); LIHC cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg16405210 chr4:1374714 KIAA1530 -0.91 -15.39 -0.64 5.49e-41 Longevity; LIHC cis rs7917772 0.582 rs4917975 chr10:104358407 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs801193 0.548 rs2659904 chr7:66178602 C/A cg10756647 chr7:56101905 PSPH 0.49 7.26 0.37 2.6e-12 Aortic root size; LIHC cis rs11122272 0.735 rs2749717 chr1:231489353 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.77 -0.5 1.77e-23 Hemoglobin concentration; LIHC cis rs1005277 0.579 rs2474575 chr10:38387901 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs9814567 1.000 rs9813774 chr3:134227100 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.29 -0.55 5.27e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs655641 0.911 rs682366 chr11:85701741 T/C cg09030501 chr11:85779252 PICALM -0.54 -6.32 -0.32 8.19e-10 Platelet count; LIHC cis rs11673344 0.864 rs7256876 chr19:37579472 G/A cg27390819 chr19:37464633 NA -0.51 -6.19 -0.32 1.73e-9 Obesity-related traits; LIHC cis rs7552404 0.960 rs12134854 chr1:76137606 A/G cg03433033 chr1:76189801 ACADM 0.63 9.16 0.44 4.88e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2108622 0.711 rs12609820 chr19:15978057 T/C cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.87e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs7619427 0.544 rs59081044 chr3:43967628 C/T cg24966902 chr3:44043705 NA 0.43 6.51 0.33 2.64e-10 Schizophrenia; LIHC cis rs921968 0.643 rs483172 chr2:219428299 A/G cg02985541 chr2:219472218 PLCD4 0.45 8.42 0.41 1.05e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs9733 0.596 rs11204697 chr1:150658971 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.15e-9 Tonsillectomy; LIHC cis rs921968 0.643 rs13431399 chr2:219469498 G/C cg02985541 chr2:219472218 PLCD4 -0.41 -6.58 -0.34 1.77e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26512142 chr11:2554198 KCNQ1 0.36 6.17 0.32 1.97e-9 Cognitive function; LIHC cis rs1385374 0.858 rs10847698 chr12:129300222 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.65 7.88 0.39 4.31e-14 Systemic lupus erythematosus; LIHC cis rs1499614 1.000 rs2707828 chr7:66171377 G/A cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC cis rs892961 0.932 rs7223768 chr17:75410521 G/A cg01320579 chr17:75405842 SEPT9 0.51 6.93 0.35 2.09e-11 Airflow obstruction; LIHC trans rs561341 0.941 rs550213 chr17:30317518 C/G cg20587970 chr11:113659929 NA -1.23 -10.64 -0.5 5.12e-23 Hip circumference adjusted for BMI; LIHC cis rs11229555 1.000 rs7102510 chr11:58371283 T/G cg15696309 chr11:58395628 NA -0.73 -8.95 -0.44 2.24e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs600806 0.778 rs2152924 chr1:110011701 G/A cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.48 -0.38 6.2e-13 Intelligence (multi-trait analysis); LIHC cis rs2073499 1.000 rs2071803 chr3:50407344 G/T cg03645007 chr3:50255295 SLC38A3 0.49 6.22 0.32 1.46e-9 Schizophrenia; LIHC trans rs2243480 1.000 rs2257790 chr7:65600450 C/T cg10756647 chr7:56101905 PSPH 1.09 13.36 0.59 4.74e-33 Diabetic kidney disease; LIHC cis rs9326778 0.520 rs11954116 chr5:108823033 A/G cg17395555 chr5:108820864 NA -0.37 -6.27 -0.32 1.09e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02097843 chr10:33269812 NA -0.46 -6.31 -0.32 8.51e-10 Pancreatic cancer; LIHC cis rs3784262 0.904 rs3784260 chr15:58253269 T/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.49 -0.33 2.97e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs244293 0.965 rs11079153 chr17:53176023 C/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs11112613 0.609 rs2374534 chr12:106047897 A/T cg03607813 chr12:105948248 NA 0.4 6.27 0.32 1.11e-9 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs2777491 0.574 rs1757468 chr15:41743574 T/A cg18705301 chr15:41695430 NDUFAF1 -1.23 -18.31 -0.7 1.14e-52 Ulcerative colitis; LIHC cis rs2204008 0.837 rs11168341 chr12:37961951 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs6748734 0.779 rs4401206 chr2:241796905 A/G cg08694578 chr2:241835147 C2orf54 -0.51 -7.84 -0.39 5.66e-14 Urinary metabolites; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20704215 chr1:35658192 SFPQ -0.53 -6.22 -0.32 1.49e-9 Systolic blood pressure; LIHC cis rs15676 0.947 rs1572912 chr9:131565554 T/C cg13708974 chr9:131466143 PKN3 -0.38 -5.83 -0.3 1.29e-8 Blood metabolite levels; LIHC cis rs9916302 0.706 rs7503081 chr17:37482673 A/G cg07936489 chr17:37558343 FBXL20 0.85 12.38 0.56 2.46e-29 Glomerular filtration rate (creatinine); LIHC trans rs60843830 1.000 rs60484953 chr2:221560 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.62 8.8 0.43 6.75e-17 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs4319547 0.688 rs6489158 chr12:123110365 T/G cg05707623 chr12:122985044 ZCCHC8 -0.53 -7.74 -0.39 1.13e-13 Body mass index; LIHC cis rs763121 0.962 rs5757130 chr22:38937794 G/A cg14440974 chr22:39074834 NA -0.34 -5.72 -0.3 2.28e-8 Menopause (age at onset); LIHC cis rs2204008 0.712 rs12371182 chr12:38321143 A/C cg26384229 chr12:38710491 ALG10B 0.86 10.72 0.5 2.7e-23 Bladder cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19874450 chr17:34900926 GGNBP2 0.52 6.95 0.35 1.81e-11 Lung function (FEV1/FVC); LIHC cis rs3960554 0.569 rs1894761 chr7:75876754 C/T cg01364799 chr7:75623366 TMEM120A 0.5 7.17 0.36 4.8e-12 Eotaxin levels; LIHC trans rs2243480 1.000 rs466983 chr7:65520496 T/G cg10756647 chr7:56101905 PSPH 1.07 13.24 0.58 1.32e-32 Diabetic kidney disease; LIHC cis rs7618501 0.602 rs6780731 chr3:50017478 A/G cg21467203 chr3:49911342 NA -0.43 -7.65 -0.38 2.01e-13 Intelligence (multi-trait analysis); LIHC cis rs1385374 0.841 rs11059929 chr12:129296893 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.67 8.01 0.4 1.81e-14 Systemic lupus erythematosus; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09807979 chr1:154909529 PMVK 0.42 6.07 0.31 3.33e-9 Cognitive function; LIHC cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg16145915 chr7:1198662 ZFAND2A -0.39 -9.77 -0.47 4.91e-20 Longevity;Endometriosis; LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.72 0.57 1.24e-30 Prudent dietary pattern; LIHC cis rs1185460 0.967 rs1784461 chr11:118937985 G/A cg23280166 chr11:118938394 VPS11 0.6 8.12 0.4 8.39e-15 Coronary artery disease; LIHC cis rs2153535 0.580 rs2327051 chr6:8441150 A/G cg21535247 chr6:8435926 SLC35B3 -0.59 -7.99 -0.4 2.03e-14 Motion sickness; LIHC cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs6674176 0.660 rs11210936 chr1:44391438 A/T cg12908607 chr1:44402522 ARTN -0.48 -8.11 -0.4 8.88e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4665809 0.652 rs6727974 chr2:26524639 A/G cg04944784 chr2:26401820 FAM59B 0.59 8.01 0.4 1.8e-14 Gut microbiome composition (summer); LIHC cis rs7945071 0.507 rs4753892 chr11:110302643 C/T cg04157658 chr11:110243994 NA 0.32 5.89 0.3 9.1e-9 Cognitive function; LIHC cis rs13118159 0.651 rs4974599 chr4:1314430 A/C cg16405210 chr4:1374714 KIAA1530 -0.68 -10.39 -0.49 3.78e-22 Longevity; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.47 0.62 2.36e-37 Prudent dietary pattern; LIHC cis rs17666538 0.585 rs4448252 chr8:615597 A/G cg23958373 chr8:599963 NA 0.75 5.77 0.3 1.79e-8 IgG glycosylation; LIHC cis rs4660306 0.961 rs2991966 chr1:45999503 G/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.65 -7.66 -0.38 1.97e-13 Homocysteine levels; LIHC cis rs6939532 0.522 rs2073528 chr6:26375143 G/C cg14345882 chr6:26364793 BTN3A2 0.39 5.81 0.3 1.45e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs6088590 1.000 rs910870 chr20:33292893 T/C cg08999081 chr20:33150536 PIGU 0.37 5.84 0.3 1.23e-8 Coronary artery disease; LIHC cis rs6570726 0.791 rs6912079 chr6:145894949 G/A cg23711669 chr6:146136114 FBXO30 0.75 13.4 0.59 3.22e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.512 rs6002474 chr22:42168181 A/G cg06634786 chr22:41940651 POLR3H 0.72 7.31 0.37 1.94e-12 Vitiligo; LIHC cis rs1707322 0.686 rs3014242 chr1:46087577 G/A cg03146154 chr1:46216737 IPP -0.55 -9.34 -0.45 1.26e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1580019 0.844 rs1901202 chr7:32503724 A/T cg06627557 chr7:32535165 LSM5;AVL9 0.98 16.75 0.67 2.13e-46 Cognitive ability; LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.5 -6.2 -0.32 1.66e-9 Diastolic blood pressure; LIHC cis rs8081395 0.651 rs1292067 chr17:57930646 A/C cg02344993 chr17:57696989 CLTC -0.51 -9.06 -0.44 1.06e-17 White blood cell count; LIHC cis rs798554 0.797 rs2107964 chr7:2863574 G/A cg19346786 chr7:2764209 NA -0.49 -6.94 -0.35 1.98e-11 Height; LIHC cis rs11122272 0.735 rs1416916 chr1:231533027 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.94e-23 Hemoglobin concentration; LIHC cis rs1371867 0.846 rs1660338 chr8:101242757 C/G cg06002616 chr8:101225028 SPAG1 -0.35 -6.25 -0.32 1.23e-9 Atrioventricular conduction; LIHC cis rs936229 0.861 rs7162232 chr15:75115895 G/A cg14664628 chr15:75095509 CSK -1.01 -20.39 -0.74 4.61e-61 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09326324 chr1:161123937 UFC1 0.46 6.41 0.33 4.82e-10 Pancreatic cancer; LIHC trans rs8058130 0.566 rs9926510 chr16:64327067 A/C cg08997518 chr6:116601248 DSE;TSPYL1 -0.44 -6.2 -0.32 1.59e-9 Schizophrenia; LIHC cis rs11640734 0.609 rs11647746 chr16:89806343 C/A cg00800038 chr16:89945340 TCF25 -0.62 -9.42 -0.45 7.05e-19 Interleukin-17 levels; LIHC cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg00149659 chr3:10157352 C3orf10 0.68 7.11 0.36 6.86e-12 Alzheimer's disease; LIHC cis rs700651 0.821 rs700666 chr2:198673544 G/A cg10820045 chr2:198174542 NA 0.47 7.03 0.36 1.12e-11 Intracranial aneurysm; LIHC trans rs12310956 0.532 rs6488187 chr12:33975029 C/T cg26384229 chr12:38710491 ALG10B 0.5 7.19 0.36 4.17e-12 Morning vs. evening chronotype; LIHC cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg11502198 chr6:26597334 ABT1 0.63 9.86 0.47 2.34e-20 Intelligence (multi-trait analysis); LIHC cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg24675658 chr1:53192096 ZYG11B 0.83 13.71 0.6 2.09e-34 Monocyte count; LIHC cis rs6960043 0.818 rs10950550 chr7:15063923 T/G cg19272540 chr7:15055459 NA 0.25 6.72 0.34 7.75e-11 Type 2 diabetes; LIHC cis rs644799 0.526 rs568120 chr11:95578734 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.59 8.35 0.41 1.69e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1144333 0.655 rs4949682 chr1:76443196 C/T cg22875332 chr1:76189707 ACADM -0.4 -5.87 -0.3 1.01e-8 Attention function in attention deficit hyperactive disorder; LIHC cis rs7107174 0.892 rs11237450 chr11:78023356 C/A cg02023728 chr11:77925099 USP35 0.52 9.83 0.47 2.95e-20 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs1855769 chr6:8473095 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.61 0.42 2.75e-16 Motion sickness; LIHC cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg11952622 chr19:58962976 ZNF324B 0.48 7.16 0.36 4.86e-12 Uric acid clearance; LIHC cis rs5753618 0.561 rs4820043 chr22:31647094 A/G cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs763121 0.853 rs4821810 chr22:39072098 C/G cg21395723 chr22:39101663 GTPBP1 0.41 6.94 0.35 1.98e-11 Menopause (age at onset); LIHC cis rs78545713 0.536 rs56119218 chr6:26225881 C/A cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs2730245 0.550 rs2788478 chr7:158672619 A/G cg23730037 chr7:158596552 ESYT2 -0.41 -6.27 -0.32 1.06e-9 Height; LIHC trans rs1005277 0.579 rs2472183 chr10:38392495 T/G cg27523141 chr10:43048294 ZNF37B 0.38 6.51 0.33 2.61e-10 Extrinsic epigenetic age acceleration; LIHC cis rs473651 0.935 rs515412 chr2:239345394 A/T cg21699342 chr2:239360505 ASB1 0.34 6.54 0.33 2.23e-10 Multiple system atrophy; LIHC cis rs611744 0.647 rs702808 chr8:109252554 T/C cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs17854409 0.881 rs6011430 chr20:61497014 C/T cg06598544 chr20:61472147 COL9A3 0.58 5.77 0.3 1.8e-8 Obesity-related traits; LIHC trans rs2273156 0.929 rs12050171 chr14:35395451 T/A cg20620338 chr15:102077239 NA -0.41 -6.07 -0.31 3.35e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs9658691 0.607 rs3740281 chr10:90772150 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.87 -6.63 -0.34 1.34e-10 Mosquito bite size; LIHC cis rs3781458 0.806 rs3781466 chr10:126328689 A/G cg20435097 chr10:126320824 FAM53B -0.71 -13.87 -0.6 5.36e-35 Male-pattern baldness; LIHC trans rs1814175 0.676 rs1851859 chr11:49860405 A/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.76 -0.73 1.56e-58 Height; LIHC cis rs4853525 0.522 rs10490538 chr2:191590066 C/T cg10560079 chr2:191398806 TMEM194B 0.41 5.82 0.3 1.38e-8 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs9733 0.596 rs12089731 chr1:150647798 T/C cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs17253792 0.822 rs77197405 chr14:56159662 T/A cg01858014 chr14:56050164 KTN1 -0.71 -7.29 -0.37 2.16e-12 Putamen volume; LIHC cis rs12220238 1.000 rs10824078 chr10:75892120 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.7 6.77 0.34 5.49e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs11971779 0.715 rs11772771 chr7:139058803 T/C cg07862535 chr7:139043722 LUC7L2 0.64 11.08 0.51 1.44e-24 Diisocyanate-induced asthma; LIHC cis rs7700895 0.578 rs147295 chr5:95219261 A/G cg10483112 chr5:95245456 ELL2 0.32 5.75 0.3 2.03e-8 IgG glycosylation; LIHC trans rs1005277 0.579 rs1780138 chr10:38501654 A/G cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg00091569 chr3:40428383 ENTPD3 0.41 6.98 0.35 1.5e-11 Renal cell carcinoma; LIHC cis rs7953508 0.506 rs930316 chr12:93967035 A/G cg18151635 chr12:93972918 NA -0.51 -8.58 -0.42 3.4e-16 Pubertal anthropometrics; LIHC cis rs55665837 0.540 rs10128681 chr11:14701576 T/C cg00085434 chr11:14927489 NA 0.41 5.81 0.3 1.41e-8 Vitamin D levels; LIHC cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg20607798 chr8:58055168 NA 0.46 5.94 0.31 6.85e-9 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.71 -10.6 -0.5 6.64e-23 Lymphocyte counts; LIHC cis rs4819052 0.684 rs914216 chr21:46698298 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.22 0.41 4.21e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7927592 0.913 rs7106339 chr11:68240241 C/T cg01657329 chr11:68192670 LRP5 -0.46 -6.02 -0.31 4.41e-9 Total body bone mineral density; LIHC cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg18225595 chr11:63971243 STIP1 0.66 8.28 0.41 2.87e-15 Mean platelet volume; LIHC cis rs72772090 0.710 rs113710451 chr5:96060306 G/A cg17330273 chr5:96107758 CAST;ERAP1 -0.65 -7.2 -0.36 3.82e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs926392 0.572 rs6129159 chr20:37675011 A/T cg16355469 chr20:37678765 NA 0.53 8.5 0.42 5.81e-16 Dialysis-related mortality; LIHC cis rs2836974 0.666 rs11910705 chr21:40685604 C/T cg11890956 chr21:40555474 PSMG1 -0.48 -7.59 -0.38 3.02e-13 Cognitive function; LIHC cis rs11098699 0.848 rs302540 chr4:124218602 T/C cg09941581 chr4:124220074 SPATA5 0.31 5.81 0.3 1.4e-8 Mosquito bite size; LIHC cis rs853679 0.517 rs17711801 chr6:28092307 C/G cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC trans rs637571 0.522 rs556643 chr11:65733289 C/T cg17712092 chr4:129076599 LARP1B 0.66 10.87 0.51 7.46e-24 Eosinophil percentage of white cells; LIHC cis rs992157 1.000 rs4674280 chr2:219141458 C/G cg00012203 chr2:219082015 ARPC2 -0.85 -13.76 -0.6 1.32e-34 Colorectal cancer; LIHC cis rs240764 0.817 rs239206 chr6:101137332 T/G cg09795085 chr6:101329169 ASCC3 0.53 7.15 0.36 5.15e-12 Neuroticism; LIHC cis rs12586317 0.547 rs12435454 chr14:35466997 A/G cg05294307 chr14:35346193 BAZ1A -0.5 -7.48 -0.37 6.41e-13 Psoriasis; LIHC trans rs10506458 1.000 rs73128794 chr12:63445313 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.19 -0.48 1.77e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs11676348 0.774 rs57545959 chr2:219047718 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.44 5.84 0.3 1.24e-8 Ulcerative colitis; LIHC cis rs12477438 0.715 rs7586608 chr2:99558017 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.56 -0.38 3.8e-13 Chronic sinus infection; LIHC trans rs72829446 0.530 rs4796424 chr17:7387973 T/C cg08566640 chr11:64091735 NA -0.67 -6.13 -0.31 2.36e-9 Androgen levels; LIHC cis rs561341 1.000 rs4795670 chr17:30244839 T/C cg12193833 chr17:30244370 NA -0.54 -5.87 -0.3 1.01e-8 Hip circumference adjusted for BMI; LIHC cis rs875971 0.545 rs7787063 chr7:65628999 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.47 0.37 6.94e-13 Aortic root size; LIHC trans rs1005277 0.505 rs200936 chr10:38134935 T/C cg17830980 chr10:43048298 ZNF37B -0.46 -8.85 -0.43 4.65e-17 Extrinsic epigenetic age acceleration; LIHC cis rs7914558 1.000 rs7896547 chr10:104866958 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.51e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7903847 0.642 rs12359257 chr10:99136359 A/T cg20016023 chr10:99160130 RRP12 -0.4 -6.41 -0.33 4.86e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10464366 0.746 rs62442210 chr7:39146328 G/T cg21665744 chr7:39171113 POU6F2 0.32 5.84 0.3 1.22e-8 IgG glycosylation; LIHC cis rs12824058 0.798 rs4759652 chr12:130808771 C/T cg24229701 chr12:130821962 PIWIL1 0.45 6.86 0.35 3.2e-11 Menopause (age at onset); LIHC cis rs4268898 0.931 rs34504814 chr2:24503766 C/T cg06627628 chr2:24431161 ITSN2 -0.56 -8.12 -0.4 8.28e-15 Asthma; LIHC trans rs911555 0.755 rs11627446 chr14:103946450 G/C cg17675199 chr6:35436792 RPL10A 0.43 8.8 0.43 7.09e-17 Intelligence (multi-trait analysis); LIHC cis rs7613875 0.578 rs2526749 chr3:50076734 A/G cg05623727 chr3:50126028 RBM5 -0.34 -5.82 -0.3 1.38e-8 Body mass index; LIHC cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg02359409 chr6:42947317 PEX6 -0.47 -6.59 -0.34 1.64e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9814567 1.000 rs13322305 chr3:134310791 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.45e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs918629 0.530 rs1458019 chr5:95253489 A/G cg10483112 chr5:95245456 ELL2 -0.38 -6.91 -0.35 2.38e-11 IgG glycosylation; LIHC cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg16262614 chr3:133464971 TF 0.28 6.4 0.33 5.13e-10 Iron status biomarkers; LIHC cis rs1983891 1.000 rs4714485 chr6:41536587 T/G cg20194872 chr6:41519635 FOXP4 0.4 6.3 0.32 9.41e-10 Prostate cancer; LIHC cis rs7429990 0.932 rs12493348 chr3:48143538 A/T cg11946769 chr3:48343235 NME6 -0.47 -6.24 -0.32 1.28e-9 Educational attainment (years of education); LIHC cis rs17152411 0.947 rs55674450 chr10:126592153 G/T cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs2290416 0.786 rs60401352 chr8:144673097 G/A cg26536354 chr8:144654954 C8orf73 0.52 6.06 0.31 3.55e-9 Attention deficit hyperactivity disorder; LIHC trans rs11098499 0.954 rs3733524 chr4:120423729 T/C cg25214090 chr10:38739885 LOC399744 0.58 9.45 0.46 5.55e-19 Corneal astigmatism; LIHC cis rs6582630 0.598 rs12823134 chr12:38514347 T/A cg26384229 chr12:38710491 ALG10B -0.49 -6.87 -0.35 3.12e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs847649 0.599 rs13232194 chr7:102742554 T/A cg18108683 chr7:102477205 FBXL13 0.43 6.47 0.33 3.35e-10 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09366861 chr1:211556286 C1orf97 0.49 6.74 0.34 6.5500000000000006e-11 Pancreatic cancer; LIHC cis rs2274273 1.000 rs7142704 chr14:55630603 C/A cg04306507 chr14:55594613 LGALS3 0.34 6.32 0.32 8.02e-10 Protein biomarker; LIHC cis rs7772486 0.790 rs6923545 chr6:146244743 A/G cg23711669 chr6:146136114 FBXO30 -0.71 -12.42 -0.56 1.74e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg07061783 chr6:25882402 NA -0.51 -6.19 -0.32 1.73e-9 Intelligence (multi-trait analysis); LIHC cis rs4409675 0.576 rs2749110 chr1:28235010 T/C cg23691781 chr1:28212827 C1orf38 0.32 7.57 0.38 3.4e-13 Corneal astigmatism; LIHC cis rs12478296 0.901 rs67951957 chr2:243004901 A/G cg18898632 chr2:242989856 NA -0.47 -6.5 -0.33 2.86e-10 Obesity-related traits; LIHC cis rs4845570 1.000 rs4845570 chr1:151759104 C/T cg07092448 chr1:151763213 TDRKH 0.7 7.82 0.39 6.8e-14 Coronary artery disease; LIHC cis rs870825 0.616 rs4437295 chr4:185643336 C/T cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs10792665 0.640 rs1114961 chr11:82622999 G/T cg24227371 chr11:82718527 RAB30 -0.27 -6.13 -0.31 2.41e-9 Obesity-related traits; LIHC cis rs208520 0.874 rs208514 chr6:66945520 G/A cg07460842 chr6:66804631 NA -0.7 -7.68 -0.38 1.73e-13 Exhaled nitric oxide output; LIHC cis rs1144333 0.655 rs5745465 chr1:76346832 A/G cg03433033 chr1:76189801 ACADM 0.53 7.21 0.36 3.51e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs67311347 0.911 rs6773917 chr3:40469254 G/T cg13409248 chr3:40428643 ENTPD3 0.4 6.7 0.34 8.52e-11 Renal cell carcinoma; LIHC cis rs8017423 0.967 rs11621364 chr14:90709115 A/G cg14092571 chr14:90743983 NA -0.36 -5.73 -0.3 2.16e-8 Mortality in heart failure; LIHC cis rs2637030 0.515 rs449160 chr5:53005969 A/G cg06476337 chr5:52856530 NDUFS4 0.42 6.71 0.34 8.25e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs6582630 0.539 rs4882324 chr12:38499180 T/C cg26384229 chr12:38710491 ALG10B -0.48 -6.72 -0.34 7.84e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs9611565 0.559 rs132765 chr22:42008068 A/G cg06634786 chr22:41940651 POLR3H 0.71 7.38 0.37 1.23e-12 Vitiligo; LIHC cis rs6121246 0.909 rs1994251 chr20:30287328 T/G cg13852791 chr20:30311386 BCL2L1 0.95 9.79 0.47 4.22e-20 Mean corpuscular hemoglobin; LIHC cis rs875971 0.895 rs3857684 chr7:65938158 G/C cg18252515 chr7:66147081 NA -0.43 -6.02 -0.31 4.43e-9 Aortic root size; LIHC cis rs7560272 0.723 rs780395 chr2:73700853 G/A cg20560298 chr2:73613845 ALMS1 0.36 5.83 0.3 1.26e-8 Schizophrenia; LIHC cis rs4975709 0.610 rs4975705 chr5:1860359 T/C cg14773178 chr5:1868261 NA 0.27 7.06 0.36 9.08e-12 Cardiovascular disease risk factors; LIHC cis rs12701220 0.522 rs12701455 chr7:1055409 A/G cg07308232 chr7:1071921 C7orf50 -0.42 -5.92 -0.31 7.69e-9 Bronchopulmonary dysplasia; LIHC cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 9.61 0.46 1.6e-19 Platelet count; LIHC cis rs3770081 1.000 rs78646493 chr2:86283195 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.95 -11.58 -0.53 2.24e-26 Facial emotion recognition (sad faces); LIHC cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs4820294 0.669 rs9622677 chr22:38054262 A/C cg00142150 chr22:38071001 LGALS1 0.44 7.48 0.38 6.14e-13 Fat distribution (HIV); LIHC cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg21724239 chr8:58056113 NA 0.66 7.89 0.39 4e-14 Developmental language disorder (linguistic errors); LIHC cis rs1790761 0.607 rs656652 chr11:67343957 C/T cg00290607 chr11:67383545 NA 0.38 5.77 0.3 1.76e-8 Mean corpuscular volume; LIHC cis rs651907 0.557 rs12629658 chr3:101356535 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 11.87 0.54 1.95e-27 Colorectal cancer; LIHC cis rs6933660 0.745 rs9322320 chr6:151751908 C/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.53 -8.13 -0.4 8.1e-15 Menarche (age at onset); LIHC cis rs910316 0.789 rs175457 chr14:75584507 C/T cg11812906 chr14:75593930 NEK9 -0.75 -14.19 -0.61 2.96e-36 Height; LIHC cis rs2120019 1.000 rs7162900 chr15:75368017 T/C cg11632617 chr15:75315747 PPCDC -0.43 -6.28 -0.32 1.04e-9 Blood trace element (Zn levels); LIHC cis rs72781680 1.000 rs7594510 chr2:24173377 A/G cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs6499255 0.951 rs10454066 chr16:69699005 A/T cg15192750 chr16:69999425 NA 0.48 6.98 0.35 1.53e-11 IgE levels; LIHC cis rs3806843 0.900 rs2563254 chr5:140142701 T/C cg19875535 chr5:140030758 IK -0.37 -5.98 -0.31 5.72e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7772486 0.875 rs2814877 chr6:146299763 C/G cg23711669 chr6:146136114 FBXO30 0.67 11.41 0.53 8.95e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7546668 1.000 rs6685648 chr1:15825195 T/C cg11706911 chr1:15910989 AGMAT 0.44 6.8 0.34 4.75e-11 Glomerular filtration rate (creatinine); LIHC cis rs963731 0.649 rs4670905 chr2:39266134 A/T cg04010122 chr2:39346883 SOS1 -0.68 -6.11 -0.31 2.73e-9 Corticobasal degeneration; LIHC cis rs17539620 0.534 rs76931320 chr6:154833508 G/A cg20019720 chr6:154832845 CNKSR3 0.43 6.24 0.32 1.31e-9 Lipoprotein (a) levels; LIHC cis rs7772486 0.875 rs9322046 chr6:146393625 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.77 0.3 1.79e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs11626933 1.000 rs61986782 chr14:90751344 C/T cg04374321 chr14:90722782 PSMC1 0.47 6.5 0.33 2.85e-10 Gut microbiota (bacterial taxa); LIHC cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg11502198 chr6:26597334 ABT1 0.59 8.99 0.44 1.74e-17 Intelligence (multi-trait analysis); LIHC cis rs12600856 1 rs12600856 chr17:38163295 T/C cg17467752 chr17:38218738 THRA 0.76 13.99 0.6 1.82e-35 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12788078 chr18:43546845 KIAA1632 0.51 6.77 0.34 5.45e-11 Pancreatic cancer; LIHC cis rs4803468 1.000 rs284649 chr19:41926838 C/T cg14132834 chr19:41945861 ATP5SL -0.46 -6.78 -0.34 5.38e-11 Height; LIHC cis rs919433 0.617 rs12619333 chr2:198567638 C/G cg10820045 chr2:198174542 NA -0.5 -7.58 -0.38 3.35e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs722599 0.501 rs2286914 chr14:75387012 T/C cg11812906 chr14:75593930 NEK9 -0.46 -7.64 -0.38 2.13e-13 IgG glycosylation; LIHC cis rs7534824 0.625 rs61782078 chr1:101498212 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.22 0.36 3.37e-12 Refractive astigmatism; LIHC cis rs6121246 0.697 rs8118150 chr20:30436088 G/A cg13852791 chr20:30311386 BCL2L1 0.9 9.12 0.44 6.73e-18 Mean corpuscular hemoglobin; LIHC cis rs1843834 0.505 rs7585047 chr2:225373897 C/T cg12698349 chr2:225449008 CUL3 0.69 10.79 0.5 1.45e-23 IgE levels in asthmatics (D.p. specific); LIHC cis rs7208859 0.562 rs11650923 chr17:29008167 G/A cg13385521 chr17:29058706 SUZ12P 0.66 6.37 0.33 6.03e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs7937682 0.602 rs11214036 chr11:111773169 C/T cg09085632 chr11:111637200 PPP2R1B -0.9 -13.7 -0.6 2.39e-34 Primary sclerosing cholangitis; LIHC cis rs2845885 1.000 rs2845885 chr11:63869062 A/G cg18375707 chr11:64034959 PLCB3 -0.42 -5.77 -0.3 1.74e-8 Body mass index; LIHC cis rs11971779 0.941 rs4732368 chr7:139034207 A/C cg07862535 chr7:139043722 LUC7L2 0.68 11.08 0.51 1.41e-24 Diisocyanate-induced asthma; LIHC cis rs7677751 0.806 rs4864860 chr4:55090021 T/C cg17187183 chr4:55093834 PDGFRA 0.66 8.34 0.41 1.85e-15 Corneal astigmatism; LIHC cis rs17106184 1.000 rs72900938 chr1:51118527 T/C cg07174182 chr1:51127561 FAF1 -0.71 -7.56 -0.38 3.65e-13 Type 2 diabetes; LIHC cis rs963731 0.649 rs297125 chr2:39314969 G/A cg04010122 chr2:39346883 SOS1 -0.68 -6.03 -0.31 4.15e-9 Corticobasal degeneration; LIHC cis rs798554 0.616 rs1636252 chr7:2884993 A/C cg13628971 chr7:2884303 GNA12 0.48 8.45 0.42 8.43e-16 Height; LIHC cis rs826838 1.000 rs1684395 chr12:39083161 T/G cg13010199 chr12:38710504 ALG10B -0.38 -5.74 -0.3 2.1e-8 Heart rate; LIHC cis rs6545883 0.929 rs1186700 chr2:61663372 A/C cg14146966 chr2:61757674 XPO1 0.44 7.55 0.38 3.97e-13 Tuberculosis; LIHC cis rs68170813 0.559 rs77671232 chr7:106939202 A/G cg02696742 chr7:106810147 HBP1 -0.49 -5.72 -0.3 2.38e-8 Coronary artery disease; LIHC cis rs922107 0.576 rs1563786 chr1:89952557 A/C cg15422784 chr1:90023713 LRRC8B -0.41 -6.31 -0.32 8.63e-10 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs754466 0.580 rs12356063 chr10:79558131 G/C cg17075019 chr10:79541650 NA -0.8 -12.74 -0.57 1.0500000000000001e-30 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2072499 0.750 rs57056972 chr1:156159064 C/A cg24450063 chr1:156163899 SLC25A44 0.76 8.22 0.41 4.36e-15 Testicular germ cell tumor; LIHC cis rs11031096 0.683 rs55898672 chr11:4189284 G/C cg18678763 chr11:4115507 RRM1 -0.41 -5.95 -0.31 6.62e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.5 -7.68 -0.38 1.64e-13 Prudent dietary pattern; LIHC cis rs6952808 0.771 rs10265944 chr7:1918337 C/T cg21782813 chr7:2030301 MAD1L1 0.42 6.9 0.35 2.48e-11 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22605943 chr3:107243790 BBX 0.47 6.14 0.32 2.3e-9 Pancreatic cancer; LIHC cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.57 0.33 1.88e-10 Bipolar disorder; LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg05527609 chr1:210001259 C1orf107 0.41 6.09 0.31 3.12e-9 Cleft lip with or without cleft palate; LIHC cis rs6687430 0.526 rs7555790 chr1:10613167 A/G cg17425144 chr1:10567563 PEX14 -0.47 -8.67 -0.42 1.7e-16 Hand grip strength; LIHC cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg11764359 chr7:65958608 NA 0.57 6.01 0.31 4.66e-9 Diabetic kidney disease; LIHC cis rs7772486 0.641 rs960385 chr6:146371074 G/A cg13319975 chr6:146136371 FBXO30 -0.53 -8.43 -0.41 9.45e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7619427 0.544 rs62252204 chr3:43965558 G/A cg24966902 chr3:44043705 NA 0.43 6.52 0.33 2.47e-10 Schizophrenia; LIHC cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg18305652 chr10:134549665 INPP5A -0.43 -6.42 -0.33 4.49e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg22963979 chr7:1858916 MAD1L1 -0.44 -6.95 -0.35 1.8e-11 Bipolar disorder and schizophrenia; LIHC cis rs853679 0.517 rs9348793 chr6:28084189 G/A cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs55823223 0.503 rs9906971 chr17:73848477 A/G cg08125733 chr17:73851984 WBP2 0.85 12.45 0.56 1.31e-29 Psoriasis; LIHC cis rs6748734 0.779 rs4401206 chr2:241796905 A/G cg20140201 chr2:241835670 C2orf54 -0.5 -7.58 -0.38 3.32e-13 Urinary metabolites; LIHC cis rs9611565 0.605 rs202638 chr22:41855458 A/G cg03806693 chr22:41940476 POLR3H 0.57 7.63 0.38 2.34e-13 Vitiligo; LIHC cis rs2836950 0.501 rs4818018 chr21:40694072 C/T cg06238570 chr21:40685208 BRWD1 -0.49 -8.0 -0.4 1.94e-14 Menarche (age at onset); LIHC cis rs9486715 0.867 rs4438964 chr6:96917563 T/G cg06623918 chr6:96969491 KIAA0776 0.84 14.73 0.62 2.23e-38 Headache; LIHC cis rs1401999 0.690 rs6768149 chr3:183636195 T/C cg05044414 chr3:183734942 ABCC5 0.32 5.87 0.3 1.05e-8 Anterior chamber depth; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg00496025 chr7:73038982 MLXIPL -0.54 -6.78 -0.34 5.19e-11 Systolic blood pressure; LIHC cis rs3857067 0.506 rs282450 chr4:95139598 G/C cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.3 -0.45 1.73e-18 QT interval; LIHC cis rs6952808 1.000 rs12699404 chr7:1894022 A/T cg14004847 chr7:1930337 MAD1L1 -0.42 -5.77 -0.3 1.76e-8 Bipolar disorder and schizophrenia; LIHC cis rs1005277 0.563 rs2800550 chr10:38482929 T/C cg25427524 chr10:38739819 LOC399744 -0.72 -14.26 -0.61 1.58e-36 Extrinsic epigenetic age acceleration; LIHC cis rs1577917 0.572 rs911927 chr6:86327860 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.29 -0.32 9.88e-10 Response to antipsychotic treatment; LIHC cis rs763014 0.966 rs4984904 chr16:680809 C/G cg00908189 chr16:619842 PIGQ 0.82 12.91 0.57 2.4e-31 Height; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg04267008 chr7:1944627 MAD1L1 -0.65 -10.47 -0.49 1.97e-22 Bipolar disorder and schizophrenia; LIHC cis rs1215050 0.791 rs260890 chr4:98741698 A/G cg05340658 chr4:99064831 C4orf37 0.39 5.76 0.3 1.89e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6430585 0.583 rs2304371 chr2:136561557 A/G cg15123519 chr2:136567270 LCT -0.39 -6.61 -0.34 1.44e-10 Corneal structure; LIHC cis rs2816062 0.813 rs6698315 chr1:18895806 A/G cg18795169 chr1:18902165 NA -0.81 -18.21 -0.7 2.71e-52 Urate levels in lean individuals; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10446143 chr21:44394730 PKNOX1 0.43 6.35 0.32 6.68e-10 Pancreatic cancer; LIHC cis rs644799 0.735 rs10831432 chr11:95516040 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.78 13.46 0.59 2.04e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1552244 0.572 rs12107622 chr3:10171898 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.89 -9.41 -0.45 7.39e-19 Alzheimer's disease; LIHC cis rs1691799 0.899 rs1168327 chr12:66728842 G/A cg16791601 chr12:66731901 HELB -0.56 -13.8 -0.6 9.24e-35 White blood cell count (basophil); LIHC cis rs765787 0.530 rs4331289 chr15:45515338 C/T cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC trans rs2727020 0.704 rs4144700 chr11:49370834 C/A cg18944383 chr4:111397179 ENPEP 0.26 6.32 0.32 8.37e-10 Coronary artery disease; LIHC cis rs7551222 0.614 rs7519417 chr1:204449952 T/C cg20240347 chr1:204465584 NA -0.33 -6.84 -0.35 3.6e-11 Schizophrenia; LIHC cis rs35110281 0.682 rs162379 chr21:44925334 A/G cg04455712 chr21:45112962 RRP1B -0.42 -7.31 -0.37 1.87e-12 Mean corpuscular volume; LIHC cis rs2153535 0.580 rs2327061 chr6:8447231 G/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.04e-16 Motion sickness; LIHC cis rs7572733 0.514 rs700686 chr2:198721054 G/A cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs6912958 0.559 rs242287 chr6:88071825 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.34 6.29 0.32 9.6e-10 Monocyte percentage of white cells; LIHC cis rs765787 0.530 rs4775819 chr15:45525966 C/T cg25801113 chr15:45476975 SHF 0.37 6.36 0.33 6.62e-10 Uric acid levels; LIHC cis rs12744310 0.887 rs12026778 chr1:41792274 C/T cg03962019 chr1:41807865 NA 0.38 6.09 0.31 2.99e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs3617 0.539 rs9985365 chr3:52953844 A/G cg18404041 chr3:52824283 ITIH1 0.43 6.42 0.33 4.56e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.861 rs60346509 chr8:58196050 G/T cg02290350 chr8:58132656 NA 0.47 9.16 0.44 4.93e-18 Developmental language disorder (linguistic errors); LIHC cis rs25645 0.502 rs7223318 chr17:38108553 G/C cg17344932 chr17:38183730 MED24;SNORD124 -0.47 -7.04 -0.36 1.04e-11 Myeloid white cell count; LIHC cis rs79149102 0.579 rs12591994 chr15:75320306 A/G cg15902774 chr15:75289873 SCAMP5 0.43 6.2 0.32 1.6e-9 Lung cancer; LIHC cis rs9733 0.596 rs6690725 chr1:150632322 T/C cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg06873352 chr17:61820015 STRADA 0.74 13.22 0.58 1.66e-32 Prudent dietary pattern; LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs10089 0.953 rs1012851 chr5:127360241 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.74 0.34 6.65e-11 Ileal carcinoids; LIHC cis rs2073300 0.609 rs34648279 chr20:23402935 T/G cg12062639 chr20:23401060 NAPB 1.03 13.28 0.58 9.93e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg11644478 chr21:40555479 PSMG1 0.79 9.74 0.47 6.09e-20 Cognitive function; LIHC cis rs2732480 0.500 rs2732461 chr12:48692802 C/A cg21466736 chr12:48725269 NA -0.71 -10.73 -0.5 2.36e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs1144333 0.850 rs1144342 chr1:76284364 A/G cg03433033 chr1:76189801 ACADM -0.56 -8.51 -0.42 5.6e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs10197940 0.578 rs2432946 chr2:152306897 G/T cg06191203 chr2:152266755 RIF1 0.43 7.52 0.38 4.82e-13 Lung cancer; LIHC cis rs6424115 1.000 rs7519554 chr1:24154566 T/A cg10978503 chr1:24200527 CNR2 -0.38 -8.97 -0.44 2.02e-17 Immature fraction of reticulocytes; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg18538332 chr22:24372958 LOC391322 -0.66 -9.87 -0.47 2.18e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4631830 0.812 rs11593361 chr10:51539156 A/G cg20129853 chr10:51489980 NA -0.4 -8.57 -0.42 3.67e-16 Prostate-specific antigen levels; LIHC cis rs5769765 1.000 rs5770728 chr22:50259984 G/A cg02269571 chr22:50332266 NA 0.6 8.49 0.42 6.17e-16 Schizophrenia; LIHC cis rs3806843 1.000 rs6885319 chr5:140200611 A/C cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10791097 0.668 rs10791102 chr11:130744977 G/A cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7927771 1.000 rs35624992 chr11:47615798 G/C cg20135002 chr11:47629003 NA -0.58 -10.07 -0.48 4.5e-21 Subjective well-being; LIHC trans rs17685 0.712 rs6976236 chr7:75741087 G/T cg19862616 chr7:65841803 NCRNA00174 0.91 18.79 0.71 1.31e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg06238570 chr21:40685208 BRWD1 0.56 6.79 0.34 4.99e-11 Cognitive function; LIHC cis rs9910055 0.530 rs11656758 chr17:42301541 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.65 9.41 0.45 7.65e-19 Total body bone mineral density; LIHC cis rs769267 0.895 rs2965183 chr19:19545696 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.54 8.14 0.4 7.23e-15 Tonsillectomy; LIHC cis rs908922 0.676 rs908927 chr1:152513338 C/G cg20991723 chr1:152506922 NA 0.59 10.53 0.49 1.17e-22 Hair morphology; LIHC cis rs250677 0.917 rs36066 chr5:148419771 A/G cg18129178 chr5:148520854 ABLIM3 -0.49 -6.54 -0.33 2.3e-10 Breast cancer; LIHC cis rs17106184 0.681 rs12354253 chr1:51148711 G/A cg07174182 chr1:51127561 FAF1 -0.6 -6.61 -0.34 1.5e-10 Type 2 diabetes; LIHC cis rs8067354 0.574 rs1296279 chr17:57965731 G/A cg13753209 chr17:57696993 CLTC 0.7 10.42 0.49 3.02e-22 Hemoglobin concentration; LIHC cis rs6952808 0.594 rs3778964 chr7:2138109 C/T cg20295408 chr7:1910781 MAD1L1 -0.41 -5.98 -0.31 5.51e-9 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs2952156 0.920 rs2934951 chr17:37833328 A/G cg00129232 chr17:37814104 STARD3 -0.52 -9.8 -0.47 3.72e-20 Asthma; LIHC cis rs317689 0.690 rs570256 chr12:69662929 A/T cg14784868 chr12:69753453 YEATS4 0.54 7.72 0.39 1.32e-13 Response to diuretic therapy; LIHC cis rs7395581 0.918 rs61896050 chr11:47309063 T/C cg26139080 chr11:47293733 MADD -0.5 -8.36 -0.41 1.59e-15 HDL cholesterol; LIHC cis rs11864453 0.713 rs12708926 chr16:72126063 T/C cg01557791 chr16:72042693 DHODH -0.47 -7.62 -0.38 2.58e-13 Fibrinogen levels; LIHC cis rs8180040 0.966 rs17476234 chr3:47326298 G/A cg16586182 chr3:47516702 SCAP 0.58 10.74 0.5 2.14e-23 Colorectal cancer; LIHC cis rs7027203 1.000 rs7856374 chr9:96529791 G/A cg14598338 chr9:96623480 NA 0.31 6.0 0.31 5.12e-9 DNA methylation (variation); LIHC cis rs9457247 0.663 rs2282860 chr6:167440244 T/C cg12798992 chr6:167411361 FGFR1OP 0.53 8.75 0.43 9.73e-17 Crohn's disease; LIHC cis rs28374715 0.528 rs7181982 chr15:41623020 C/G cg18705301 chr15:41695430 NDUFAF1 -1.21 -16.78 -0.67 1.55e-46 Ulcerative colitis; LIHC cis rs6963495 0.818 rs116845562 chr7:105217038 T/C cg19920283 chr7:105172520 RINT1 0.68 6.26 0.32 1.15e-9 Bipolar disorder (body mass index interaction); LIHC cis rs11098499 0.691 rs9995716 chr4:120264996 T/C cg09307838 chr4:120376055 NA 0.62 9.75 0.47 5.8e-20 Corneal astigmatism; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg24209194 chr3:40518798 ZNF619 0.64 9.72 0.47 7.11e-20 Renal cell carcinoma; LIHC cis rs8180040 0.764 rs11708451 chr3:47198826 G/A cg02527881 chr3:46936655 PTH1R -0.32 -6.33 -0.32 7.83e-10 Colorectal cancer; LIHC cis rs1030268 0.640 rs12707092 chr7:133188145 C/G cg10665199 chr7:133106180 EXOC4 0.5 5.93 0.31 7.54e-9 Intelligence (multi-trait analysis); LIHC cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.59 8.43 0.41 9.78e-16 Lymphocyte counts; LIHC cis rs2204008 0.806 rs11520229 chr12:38246448 C/A cg26384229 chr12:38710491 ALG10B 0.87 10.83 0.51 1.06e-23 Bladder cancer; LIHC trans rs875971 0.545 rs10950029 chr7:65634321 A/C cg26939375 chr7:64535504 NA 0.4 6.45 0.33 3.81e-10 Aortic root size; LIHC cis rs17685 0.725 rs6947068 chr7:75662056 T/C cg04610667 chr7:75704037 NA 0.33 5.94 0.31 6.91e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs807029 0.533 rs67692077 chr10:102740271 T/C cg27255678 chr10:102756921 LZTS2 0.52 7.41 0.37 9.92e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg25894440 chr7:65020034 NA -0.56 -6.51 -0.33 2.69e-10 Diabetic kidney disease; LIHC cis rs3796352 1.000 rs13072395 chr3:52980573 T/C cg07884673 chr3:53033167 SFMBT1 0.94 6.76 0.34 5.92e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs9393692 0.905 rs7450556 chr6:26299900 C/T cg00631329 chr6:26305371 NA -0.46 -7.75 -0.39 1.07e-13 Educational attainment; LIHC cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg12463550 chr7:65579703 CRCP 0.68 7.32 0.37 1.82e-12 Diabetic kidney disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14984255 chr18:11908827 MPPE1 -0.43 -6.22 -0.32 1.42e-9 Systolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21705394 chr11:30344510 C11orf46 0.43 6.25 0.32 1.23e-9 Cognitive function; LIHC cis rs9814567 1.000 rs9884031 chr3:134256500 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6594499 0.872 rs6881147 chr5:110451936 G/C cg04022379 chr5:110408740 TSLP 0.49 8.19 0.4 5.39e-15 Allergic disease (asthma, hay fever or eczema); LIHC trans rs10506458 1.000 rs17763435 chr12:63416511 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B 0.7 10.17 0.48 2.07e-21 Hemostatic factors and hematological phenotypes; LIHC trans rs1945213 0.694 rs17149976 chr11:55839746 T/C cg03929089 chr4:120376271 NA 0.53 6.8 0.35 4.54e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs7116495 1.000 rs73543609 chr11:71816619 G/T cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg11905131 chr22:24372483 LOC391322 -0.69 -10.63 -0.5 5.38e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6582630 0.502 rs11182760 chr12:38606273 A/T cg26384229 chr12:38710491 ALG10B 0.95 12.41 0.56 1.92e-29 Drug-induced liver injury (flucloxacillin); LIHC cis rs1538970 0.961 rs884962 chr1:45847981 G/A cg24296786 chr1:45957014 TESK2 -0.49 -7.28 -0.37 2.34e-12 Platelet count; LIHC cis rs8180040 0.726 rs4682844 chr3:46982737 T/C cg16586182 chr3:47516702 SCAP 0.5 8.83 0.43 5.53e-17 Colorectal cancer; LIHC cis rs6442522 0.560 rs924811 chr3:15516820 C/T cg16303742 chr3:15540471 COLQ 0.36 5.88 0.3 9.85e-9 Uric acid levels; LIHC cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg22963979 chr7:1858916 MAD1L1 -0.37 -6.0 -0.31 5.05e-9 Bipolar disorder and schizophrenia; LIHC cis rs2731664 0.792 rs163199 chr5:176890067 A/G cg23176889 chr5:176863531 GRK6 -0.7 -12.35 -0.56 3.18e-29 Intelligence (multi-trait analysis); LIHC cis rs911119 0.955 rs8116859 chr20:23590703 A/T cg16589663 chr20:23618590 CST3 0.72 7.54 0.38 4.32e-13 Chronic kidney disease; LIHC cis rs9549328 0.879 rs12428058 chr13:113636504 G/A cg00071026 chr13:113650936 MCF2L -0.37 -5.85 -0.3 1.17e-8 Systolic blood pressure; LIHC cis rs9611565 0.546 rs2092274 chr22:42123737 A/G cg06634786 chr22:41940651 POLR3H 0.6 6.57 0.33 1.84e-10 Vitiligo; LIHC trans rs867371 0.762 rs12905578 chr15:82581264 T/G cg18393722 chr15:85113863 UBE2QP1 0.44 7.41 0.37 9.92e-13 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21438664 chr14:21738093 HNRNPC -0.48 -6.22 -0.32 1.47e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9910055 0.552 rs4793084 chr17:42317371 G/T cg13607699 chr17:42295918 UBTF -0.75 -15.01 -0.63 1.71e-39 Total body bone mineral density; LIHC cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.638 rs10278816 chr7:66036987 T/C cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC cis rs8062405 1.000 rs55830740 chr16:28847149 G/C cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6748734 1.000 rs10933518 chr2:241838091 A/C cg09990169 chr2:241835740 C2orf54 -0.71 -11.43 -0.53 7.88e-26 Urinary metabolites; LIHC cis rs2576037 0.526 rs2571027 chr18:44561516 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.7 -10.99 -0.51 2.84e-24 Personality dimensions; LIHC cis rs12824058 0.831 rs7299065 chr12:130809661 A/T cg24838063 chr12:130822603 PIWIL1 0.67 9.96 0.47 1.1e-20 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25120630 chr11:14380003 RRAS2 0.45 6.25 0.32 1.24e-9 Lung function (FEV1/FVC); LIHC cis rs1008375 0.932 rs12500912 chr4:17603318 C/T cg02297831 chr4:17616191 MED28 0.4 5.78 0.3 1.65e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs708547 0.647 rs2293175 chr4:57861358 C/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.69 12.33 0.55 3.61e-29 Response to bleomycin (chromatid breaks); LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg16993936 chr10:13146903 OPTN 0.59 6.43 0.33 4.31e-10 Mean platelet volume; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg17713864 chr17:48784765 ANKRD40 -0.46 -6.89 -0.35 2.71e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs434216 0.526 rs2270501 chr16:85932988 A/G cg13603099 chr10:45454574 RASSF4 -0.55 -6.06 -0.31 3.67e-9 Monocyte count; LIHC cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg08499158 chr17:42289980 UBTF 0.5 8.13 0.4 8.04e-15 Total body bone mineral density; LIHC cis rs6684514 1.000 rs2273833 chr1:156233189 C/T cg16558208 chr1:156270281 VHLL 0.53 9.59 0.46 1.92e-19 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs11758351 0.866 rs75091077 chr6:26207546 A/C cg03854865 chr6:26224070 HIST1H3E 0.62 7.11 0.36 6.65e-12 Gout;Renal underexcretion gout; LIHC cis rs10752881 0.839 rs6692207 chr1:183085304 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.54 0.5 1.12e-22 Colorectal cancer; LIHC trans rs61931739 0.517 rs7139189 chr12:34319757 T/C cg26384229 chr12:38710491 ALG10B 0.48 6.42 0.33 4.6e-10 Morning vs. evening chronotype; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs67478160 0.634 rs941475 chr14:104240618 A/C cg01849466 chr14:104193079 ZFYVE21 -0.54 -9.43 -0.45 6.2800000000000005e-19 Schizophrenia; LIHC cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg10217327 chr6:118973057 C6orf204 0.63 6.07 0.31 3.46e-9 Diastolic blood pressure; LIHC cis rs736408 0.608 rs4687657 chr3:52852538 G/T cg18404041 chr3:52824283 ITIH1 -0.43 -6.25 -0.32 1.22e-9 Bipolar disorder; LIHC cis rs10752881 0.809 rs3738829 chr1:183113862 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 3.82e-23 Colorectal cancer; LIHC cis rs2832191 0.755 rs55671430 chr21:30492421 G/C cg24692254 chr21:30365293 RNF160 -0.6 -10.47 -0.49 1.94e-22 Dental caries; LIHC cis rs7589728 0.844 rs77144652 chr2:88496684 G/A cg04511125 chr2:88470314 THNSL2 0.9 8.67 0.42 1.7e-16 Plasma clusterin levels; LIHC cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg08687515 chr19:58661962 ZNF329 0.98 7.56 0.38 3.82e-13 Cholesterol, total; LIHC cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg27297192 chr10:134578999 INPP5A 0.55 7.56 0.38 3.74e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs75804782 0.691 rs55886641 chr2:239319185 T/C cg01134436 chr17:81009848 B3GNTL1 0.81 6.6 0.34 1.61e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.38 5.83 0.3 1.3e-8 Schizophrenia; LIHC trans rs783540 1.000 rs11637433 chr15:83321336 A/G cg18393722 chr15:85113863 UBE2QP1 0.39 6.86 0.35 3.19e-11 Schizophrenia; LIHC cis rs11098499 0.644 rs3986377 chr4:120260270 G/A cg09307838 chr4:120376055 NA 0.62 9.84 0.47 2.87e-20 Corneal astigmatism; LIHC cis rs763014 1.000 rs7205409 chr16:642610 A/G cg09263875 chr16:632152 PIGQ 0.44 7.26 0.37 2.68e-12 Height; LIHC cis rs208520 0.690 rs74707865 chr6:66717352 A/G cg07460842 chr6:66804631 NA 0.78 9.0 0.44 1.62e-17 Exhaled nitric oxide output; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg00907843 chr7:73038888 MLXIPL 0.47 6.56 0.33 2.04e-10 Hepatitis; LIHC cis rs611744 0.647 rs7015513 chr8:109262570 A/C cg18478394 chr8:109455254 TTC35 0.39 6.78 0.34 5.24e-11 Dupuytren's disease; LIHC cis rs2439831 0.571 rs689883 chr15:43812596 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 7.29 0.37 2.14e-12 Lung cancer in ever smokers; LIHC cis rs10911251 0.508 rs944970 chr1:183112566 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 3.82e-23 Colorectal cancer; LIHC cis rs4742903 0.967 rs7871759 chr9:106865438 A/G cg14250997 chr9:106856677 SMC2 0.43 7.47 0.37 6.91e-13 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs2045966 0.881 rs528412 chr8:98473089 T/C cg21278164 chr1:226127694 LEFTY2 -0.64 -6.18 -0.32 1.84e-9 nicotine metabolite ratio in current smokers; LIHC trans rs1814175 0.587 rs847628 chr11:49927064 A/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs8072100 1.000 rs8065669 chr17:45724996 G/A cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.36 -5.92 -0.3 8.05e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2412488 0.927 rs17520800 chr4:54338721 A/C cg22241045 chr4:54363911 LNX1 -0.42 -6.77 -0.34 5.53e-11 DNA methylation (variation); LIHC trans rs79976124 0.837 rs12194087 chr6:66644399 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.76 0.34 5.97e-11 Type 2 diabetes; LIHC cis rs3823572 0.586 rs2001282 chr7:133663287 A/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs6933660 0.800 rs6930557 chr6:151755806 G/A cg14262678 chr6:151773367 RMND1;C6orf211 0.5 7.39 0.37 1.12e-12 Menarche (age at onset); LIHC cis rs3741151 1.000 rs76610873 chr11:73084387 C/T cg17517138 chr11:73019481 ARHGEF17 0.87 6.38 0.33 5.92e-10 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs965469 1.000 rs2236104 chr20:3277602 C/A cg25506879 chr20:3388711 C20orf194 -0.57 -6.83 -0.35 3.86e-11 IFN-related cytopenia; LIHC cis rs7208859 0.673 rs73263785 chr17:29214808 C/T cg13385521 chr17:29058706 SUZ12P 0.82 7.93 0.39 3.19e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1707322 0.721 rs10749856 chr1:46164846 A/T cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6433857 0.657 rs2368177 chr2:181501242 T/C cg23363182 chr2:181467187 NA -0.36 -5.84 -0.3 1.2e-8 Body mass index; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg06873352 chr17:61820015 STRADA 0.73 13.29 0.58 8.47e-33 Prudent dietary pattern; LIHC cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg21644426 chr2:191273491 MFSD6 -0.53 -7.38 -0.37 1.22e-12 Pulse pressure; LIHC cis rs35306767 0.903 rs11253488 chr10:922482 G/C cg20503657 chr10:835505 NA 1.04 11.8 0.54 3.36e-27 Eosinophil percentage of granulocytes; LIHC cis rs11628318 0.614 rs7149667 chr14:103129441 G/A cg01864069 chr14:103024347 NA 0.45 6.97 0.35 1.62e-11 Platelet count; LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg11070056 chr1:107600091 PRMT6 0.63 10.75 0.5 2.04e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2346177 0.844 rs4953371 chr2:46651143 T/A cg02822958 chr2:46747628 ATP6V1E2 0.39 6.01 0.31 4.81e-9 HDL cholesterol; LIHC cis rs3736485 0.966 rs8041514 chr15:51866054 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs763014 0.932 rs2269560 chr16:682442 A/C cg07343612 chr16:622815 PIGQ -0.86 -14.98 -0.63 2.28e-39 Height; LIHC cis rs8062405 0.755 rs4788076 chr16:28570005 C/T cg00204512 chr16:28754710 NA 0.4 7.12 0.36 6.43e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6061231 0.958 rs2379126 chr20:60953005 C/A cg03945807 chr20:60948434 NA 0.44 6.81 0.35 4.32e-11 Colorectal cancer; LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg08219700 chr8:58056026 NA 0.51 6.92 0.35 2.3e-11 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg09417038 chr21:47716443 C21orf57 -0.51 -7.56 -0.38 3.78e-13 Testicular germ cell tumor; LIHC trans rs1005277 0.579 rs2505196 chr10:38393563 G/A cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg02353165 chr6:42928485 GNMT 0.77 11.82 0.54 2.95e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs11583043 0.958 rs12746722 chr1:101464789 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.17 0.4 6.23e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs904251 0.523 rs2776871 chr6:37481759 A/G cg08126542 chr6:37504118 NA -0.37 -6.29 -0.32 9.51e-10 Cognitive performance; LIHC cis rs11792861 0.962 rs3750452 chr9:111801353 T/C cg13535736 chr9:111863775 C9orf5 -0.42 -6.39 -0.33 5.28e-10 Menarche (age at onset); LIHC cis rs6456156 0.586 rs12213683 chr6:167460718 G/A cg12798992 chr6:167411361 FGFR1OP 0.43 6.73 0.34 7.25e-11 Primary biliary cholangitis; LIHC cis rs1577917 1.000 rs12209127 chr6:86724427 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.88 -0.35 2.82e-11 Response to antipsychotic treatment; LIHC cis rs332507 0.830 rs62265580 chr3:124359842 C/T cg05980111 chr3:124395277 KALRN 0.4 6.15 0.32 2.2e-9 Plateletcrit; LIHC cis rs1707322 0.964 rs7512395 chr1:46361177 G/A cg03146154 chr1:46216737 IPP 0.47 7.37 0.37 1.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1401999 1.000 rs13317532 chr3:183641669 G/C cg05044414 chr3:183734942 ABCC5 0.34 5.95 0.31 6.7e-9 Anterior chamber depth; LIHC cis rs10789491 1.000 rs1545206 chr1:47185082 C/G cg15501359 chr1:47185051 KIAA0494 0.77 10.74 0.5 2.21e-23 Response to hepatitis C treatment; LIHC cis rs3617 0.599 rs12487379 chr3:52895785 G/A cg18404041 chr3:52824283 ITIH1 -0.39 -5.74 -0.3 2.11e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9611565 0.614 rs4822053 chr22:42212936 C/A cg06634786 chr22:41940651 POLR3H -0.59 -6.69 -0.34 8.93e-11 Vitiligo; LIHC cis rs7106204 0.590 rs28864378 chr11:24206582 C/A ch.11.24196551F chr11:24239977 NA 0.77 9.51 0.46 3.42e-19 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6545883 0.826 rs2694617 chr2:61537214 G/A cg15711740 chr2:61764176 XPO1 0.42 5.89 0.3 9.25e-9 Tuberculosis; LIHC cis rs3736757 0.664 rs12567226 chr1:184678290 C/T cg07817967 chr1:184721222 EDEM3 0.38 6.04 0.31 4.05e-9 Obesity-related traits; LIHC cis rs3008870 1.000 rs3008873 chr1:67425770 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.29 0.66 1.46e-44 Lymphocyte percentage of white cells; LIHC cis rs2274273 0.837 rs11625968 chr14:55801004 G/C cg01864836 chr14:55583639 NA -0.4 -7.32 -0.37 1.79e-12 Protein biomarker; LIHC cis rs6690583 0.623 rs6679539 chr1:85479457 G/T cg22153463 chr1:85462885 MCOLN2 -0.47 -5.88 -0.3 9.72e-9 Serum sulfate level; LIHC cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg21724239 chr8:58056113 NA 0.49 6.46 0.33 3.6e-10 Developmental language disorder (linguistic errors); LIHC cis rs853679 0.517 rs9380060 chr6:28132603 G/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs875971 0.862 rs6947339 chr7:65888470 T/C cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg05025164 chr4:1340916 KIAA1530 0.74 11.21 0.52 4.89e-25 Longevity; LIHC cis rs1577917 1.000 rs10944169 chr6:86683036 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.38 -6.18 -0.32 1.79e-9 Response to antipsychotic treatment; LIHC cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 7.37 0.37 1.29e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs11671005 0.779 rs11670125 chr19:58987390 G/T cg25952890 chr19:58913133 NA 0.73 7.37 0.37 1.26e-12 Mean platelet volume; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg14828511 chr1:107599125 PRMT6 -0.44 -6.28 -0.32 1.05e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4423214 0.559 rs11234042 chr11:71239086 C/A cg05163923 chr11:71159392 DHCR7 -0.61 -7.49 -0.38 6.04e-13 Vitamin D levels; LIHC cis rs1707322 0.752 rs28719889 chr1:46202283 C/T cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12142240 0.660 rs112560929 chr1:46822297 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs1707322 1.000 rs785480 chr1:46492164 C/G cg03146154 chr1:46216737 IPP 0.48 7.85 0.39 5.49e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg00280220 chr17:61926910 NA 0.42 6.76 0.34 6.1e-11 Prudent dietary pattern; LIHC cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg02931644 chr1:25747376 RHCE -0.33 -7.06 -0.36 9.29e-12 Erythrocyte sedimentation rate; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg24846343 chr22:24311635 DDTL 0.74 15.44 0.64 3.6e-41 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7107174 1.000 rs2510049 chr11:77985459 G/T cg02023728 chr11:77925099 USP35 0.49 9.39 0.45 8.68e-19 Testicular germ cell tumor; LIHC cis rs651907 0.514 rs10936744 chr3:101433440 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.65 0.5 4.64e-23 Colorectal cancer; LIHC cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg13047869 chr3:10149882 C3orf24 0.5 6.41 0.33 4.96e-10 Alzheimer's disease; LIHC cis rs8044995 0.563 rs56331745 chr16:68368770 G/T cg03983715 chr16:68378420 PRMT7 -0.52 -6.13 -0.31 2.43e-9 Schizophrenia; LIHC cis rs4853036 0.951 rs6718298 chr2:70145450 A/C cg02498382 chr2:70120550 SNRNP27 -0.43 -6.95 -0.35 1.91e-11 Colorectal or endometrial cancer; LIHC cis rs344364 0.511 rs2982449 chr16:1947878 C/G cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs62158211 1.000 rs62158211 chr2:114106139 G/T cg17784749 chr2:114082611 LOC440839 0.62 7.4 0.37 1.09e-12 Sleep duration (oversleepers vs undersleepers);Sleep traits (multi-trait analysis);Sleep duration; LIHC trans rs60843830 1.000 rs58461606 chr2:267367 G/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.48 0.46 4.51e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs4834770 1.000 rs2282688 chr4:120243722 T/C cg09307838 chr4:120376055 NA 0.43 6.5 0.33 2.87e-10 Blood protein levels; LIHC cis rs35110281 0.667 rs2838354 chr21:45119857 T/C cg21573476 chr21:45109991 RRP1B -0.56 -10.96 -0.51 3.74e-24 Mean corpuscular volume; LIHC cis rs10847980 0.590 rs1979236 chr12:123325993 G/A cg25930673 chr12:123319894 HIP1R 1.04 11.55 0.53 2.78e-26 Adiponectin levels; LIHC cis rs2153535 0.580 rs7753192 chr6:8482637 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs9911578 0.933 rs2632508 chr17:56533235 G/A cg05425664 chr17:57184151 TRIM37 -0.59 -8.69 -0.43 1.51e-16 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.580 rs11246363 chr11:971667 T/C cg10932868 chr11:921992 NA 0.4 7.66 0.38 1.99e-13 Alzheimer's disease (late onset); LIHC cis rs2239547 0.522 rs9831409 chr3:52985711 A/T cg11645453 chr3:52864694 ITIH4 -0.23 -5.86 -0.3 1.08e-8 Schizophrenia; LIHC cis rs9911578 0.967 rs9894274 chr17:56977919 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs2412488 1.000 rs6554106 chr4:54292791 A/G cg22241045 chr4:54363911 LNX1 -0.47 -7.48 -0.37 6.52e-13 DNA methylation (variation); LIHC cis rs4332037 0.950 rs11767515 chr7:1941051 C/T cg23422044 chr7:1970798 MAD1L1 -0.64 -7.33 -0.37 1.67e-12 Bipolar disorder; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09100988 chr11:66725961 PC 0.51 6.79 0.34 5.11e-11 Hepatitis; LIHC trans rs7613875 0.600 rs1061474 chr3:50144951 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.42 -6.43 -0.33 4.39e-10 Body mass index; LIHC cis rs1865760 0.566 rs9348706 chr6:26065481 G/C cg18357526 chr6:26021779 HIST1H4A 0.46 6.79 0.34 5.03e-11 Height; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg13692902 chr5:34915868 BRIX1;RAD1 -0.37 -6.14 -0.32 2.25e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs9325144 0.647 rs11168104 chr12:38857616 G/T cg26384229 chr12:38710491 ALG10B -0.56 -7.64 -0.38 2.14e-13 Morning vs. evening chronotype; LIHC cis rs3892630 0.878 rs7246451 chr19:33209614 C/G cg22980127 chr19:33182716 NUDT19 0.98 11.65 0.53 1.24e-26 Red blood cell traits; LIHC cis rs55702914 0.905 rs787988 chr2:198200802 C/T cg10820045 chr2:198174542 NA -0.38 -5.79 -0.3 1.63e-8 Major depression and alcohol dependence; LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg00800038 chr16:89945340 TCF25 -0.68 -10.63 -0.5 5.19e-23 Skin colour saturation; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg09171127 chr8:8751325 MFHAS1 0.69 6.07 0.31 3.39e-9 Musician's dystonia; LIHC cis rs829883 0.639 rs829898 chr12:98857675 A/C cg25150519 chr12:98850993 NA 0.7 11.21 0.52 4.79e-25 Colorectal adenoma (advanced); LIHC cis rs9309473 1.000 rs11689392 chr2:73622026 T/C cg20560298 chr2:73613845 ALMS1 -0.58 -7.14 -0.36 5.59e-12 Metabolite levels; LIHC trans rs10483554 0.607 rs2816787 chr14:49721727 A/G cg21853235 chr3:50388532 TUSC4;CYB561D2 -0.51 -6.24 -0.32 1.26e-9 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; LIHC cis rs3093024 0.595 rs4412174 chr6:167476066 A/G cg23791538 chr6:167370224 RNASET2 -0.52 -7.84 -0.39 5.82e-14 Rheumatoid arthritis; LIHC cis rs2273156 0.706 rs7153331 chr14:35501670 A/G cg16230307 chr14:35515116 FAM177A1 -0.43 -6.16 -0.32 2.01e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC trans rs1814175 0.645 rs28634872 chr11:50042175 T/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs7552404 0.824 rs1251077 chr1:76189745 C/G cg22875332 chr1:76189707 ACADM -0.56 -12.11 -0.55 2.43e-28 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6442522 0.606 rs13093164 chr3:15493818 C/T cg16303742 chr3:15540471 COLQ 0.39 6.41 0.33 4.81e-10 Uric acid levels; LIHC cis rs7312933 1.000 rs11181308 chr12:42445259 A/G cg01256987 chr12:42539512 GXYLT1 -0.4 -6.62 -0.34 1.42e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs8180040 0.726 rs7628747 chr3:47001990 A/T cg02527881 chr3:46936655 PTH1R -0.35 -6.93 -0.35 2.09e-11 Colorectal cancer; LIHC cis rs9649213 0.574 rs6961790 chr7:98007993 C/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.81e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs6088590 0.931 rs6088617 chr20:33408036 G/A cg24642439 chr20:33292090 TP53INP2 0.77 10.43 0.49 2.66e-22 Coronary artery disease; LIHC cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1355223 1.000 rs11604069 chr11:34764251 A/G cg11058730 chr11:34937778 PDHX;APIP -0.42 -5.88 -0.3 9.93e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs459482 1.000 rs464783 chr21:42796480 A/G cg14166395 chr21:42792516 MX1 -0.67 -9.77 -0.47 4.9e-20 IgG glycosylation; LIHC cis rs10744422 0.925 rs3825143 chr12:123352179 C/T cg22842854 chr12:123319900 HIP1R -0.68 -8.81 -0.43 6.39e-17 Schizophrenia; LIHC cis rs2842992 0.789 rs2295901 chr6:160201295 C/A cg16489826 chr6:160211363 TCP1;MRPL18 0.48 8.49 0.42 6.2e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs7107174 0.892 rs4944196 chr11:78008731 G/A cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg16405210 chr4:1374714 KIAA1530 0.44 6.53 0.33 2.32e-10 Obesity-related traits; LIHC cis rs4920343 0.698 rs510843 chr1:19090080 C/T cg19637330 chr1:19110922 NA -0.32 -5.85 -0.3 1.16e-8 Knee osteoarthritis; LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg13126279 chr21:47581558 C21orf56 0.47 7.78 0.39 8.92e-14 Testicular germ cell tumor; LIHC cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg04546413 chr19:29218101 NA 0.57 9.95 0.47 1.17e-20 Methadone dose in opioid dependence; LIHC cis rs9814567 0.752 rs4634170 chr3:134335471 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.57 -9.09 -0.44 8.15e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs986417 1.000 rs2351175 chr14:61066730 C/T cg27398547 chr14:60952738 C14orf39 0.64 6.54 0.33 2.27e-10 Gut microbiota (bacterial taxa); LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.49 7.18 0.36 4.4e-12 Lymphocyte counts; LIHC cis rs6570726 0.935 rs367612 chr6:145828987 A/G cg23711669 chr6:146136114 FBXO30 0.54 9.75 0.47 5.8e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6500602 0.647 rs4786501 chr16:4536165 G/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.48 -7.39 -0.37 1.13e-12 Schizophrenia; LIHC cis rs80234489 1 rs80234489 chr12:31441179 A/C cg15935736 chr12:31476933 FAM60A;FLJ13224 0.65 6.05 0.31 3.75e-9 Body mass index; LIHC cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.43 -0.56 1.59e-29 Alzheimer's disease; LIHC cis rs986417 0.818 rs1950315 chr14:61000031 A/C cg27398547 chr14:60952738 C14orf39 0.74 8.26 0.41 3.28e-15 Gut microbiota (bacterial taxa); LIHC cis rs1046896 0.961 rs7208565 chr17:80696692 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.46 6.95 0.35 1.81e-11 Glycated hemoglobin levels; LIHC cis rs9911578 1.000 rs12453049 chr17:56611372 C/T cg05425664 chr17:57184151 TRIM37 0.59 8.8 0.43 6.85e-17 Intelligence (multi-trait analysis); LIHC cis rs6138458 0.626 rs6132789 chr20:25012809 C/T cg26195577 chr20:24973756 C20orf3 -0.71 -8.88 -0.43 3.75e-17 Blood protein levels; LIHC cis rs1577917 0.538 rs7755996 chr6:86423720 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.49 9.74 0.47 6.23e-20 Response to antipsychotic treatment; LIHC cis rs6964587 1.000 rs6952671 chr7:91597934 C/A cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1e-57 Breast cancer; LIHC cis rs5769765 0.955 rs5769767 chr22:50276909 G/A cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs2933343 0.700 rs1683777 chr3:128624880 T/G cg24203234 chr3:128598194 ACAD9 0.45 6.29 0.32 9.77e-10 IgG glycosylation; LIHC cis rs6964587 1.000 rs10228800 chr7:91610111 T/G cg17063962 chr7:91808500 NA 1.01 19.04 0.72 1.3e-55 Breast cancer; LIHC cis rs6748734 0.779 rs6437371 chr2:241797424 G/C cg04034577 chr2:241836375 C2orf54 -0.44 -10.06 -0.48 5.14e-21 Urinary metabolites; LIHC cis rs2066819 1.000 rs76151170 chr12:56659320 C/T cg26714650 chr12:56694279 CS -1.37 -13.18 -0.58 2.33e-32 Psoriasis vulgaris; LIHC cis rs2153535 0.580 rs9406158 chr6:8464152 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg14983838 chr19:29218262 NA 0.48 7.46 0.37 7.27e-13 Methadone dose in opioid dependence; LIHC cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg02359409 chr6:42947317 PEX6 -0.47 -6.27 -0.32 1.11e-9 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs2243480 1.000 rs4718270 chr7:65202407 A/G cg10756647 chr7:56101905 PSPH 1.11 13.62 0.59 4.91e-34 Diabetic kidney disease; LIHC cis rs17345786 0.906 rs55710435 chr3:101180330 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.57 7.16 0.36 4.83e-12 Colonoscopy-negative controls vs population controls; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg04711526 chr14:92582519 NDUFB1 0.43 6.91 0.35 2.44e-11 Alopecia areata; LIHC cis rs10876993 0.672 rs2640611 chr12:58037757 T/A cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.44 -0.33 3.95e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs1580019 0.510 rs4723162 chr7:32543804 C/A cg14728415 chr7:32535168 LSM5;AVL9 0.42 5.99 0.31 5.35e-9 Cognitive ability; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13475977 chr13:21047397 CRYL1 0.4 6.27 0.32 1.09e-9 Longevity; LIHC cis rs1816752 0.837 rs7324645 chr13:25000855 A/G cg22771759 chr13:24902376 NA 0.32 6.69 0.34 9.05e-11 Obesity-related traits; LIHC cis rs748404 0.660 rs2249952 chr15:43720533 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.1e-13 Lung cancer; LIHC trans rs2727020 0.619 rs11040300 chr11:49269984 C/A cg03929089 chr4:120376271 NA 0.67 9.47 0.46 4.65e-19 Coronary artery disease; LIHC cis rs988712 0.705 rs35051342 chr11:27634373 G/C cg18117895 chr11:27722066 BDNF 0.44 5.85 0.3 1.16e-8 Obesity; LIHC cis rs6942756 0.806 rs2566877 chr7:128897317 G/A cg02491457 chr7:128862824 NA 0.67 11.01 0.51 2.37e-24 White matter hyperintensity burden; LIHC cis rs34779708 0.966 rs1478463 chr10:35473035 G/A cg04310649 chr10:35416472 CREM -0.43 -5.85 -0.3 1.13e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9902453 0.765 rs12601647 chr17:28164953 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 13.96 0.6 2.37e-35 Coffee consumption (cups per day); LIHC cis rs7412746 0.658 rs10305711 chr1:150802996 T/C cg17724175 chr1:150552817 MCL1 0.47 9.29 0.45 1.87e-18 Melanoma; LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.638 rs35986979 chr7:66088990 G/A cg14393609 chr7:65229607 NA -0.37 -5.74 -0.3 2.06e-8 Aortic root size; LIHC cis rs35110281 0.744 rs162398 chr21:44949285 T/C cg04455712 chr21:45112962 RRP1B 0.44 7.31 0.37 1.94e-12 Mean corpuscular volume; LIHC cis rs7044106 0.791 rs10985000 chr9:123484115 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.2 0.52 5.37e-25 Hip circumference adjusted for BMI; LIHC cis rs2153535 0.580 rs2327060 chr6:8447111 G/A cg23788917 chr6:8435910 SLC35B3 0.63 8.9 0.43 3.44e-17 Motion sickness; LIHC cis rs10870270 0.957 rs9971084 chr10:133788747 G/C cg17892150 chr10:133769511 PPP2R2D -0.67 -12.35 -0.56 3.03e-29 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2153535 0.580 rs2143354 chr6:8517907 G/A cg21535247 chr6:8435926 SLC35B3 0.63 8.29 0.41 2.68e-15 Motion sickness; LIHC cis rs10789491 1.000 rs35861275 chr1:47171909 A/C cg15501359 chr1:47185051 KIAA0494 -0.79 -11.13 -0.52 9.43e-25 Response to hepatitis C treatment; LIHC cis rs651907 0.535 rs34161138 chr3:101510388 T/C cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC trans rs60843830 1.000 rs59937473 chr2:271797 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.65 9.46 0.46 5.24e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.85 -0.35 3.51e-11 Diastolic blood pressure; LIHC cis rs4764124 0.646 rs10744078 chr12:14978535 T/G cg19759883 chr12:14956454 WBP11;C12orf60 -0.47 -8.06 -0.4 1.32e-14 Pubertal anthropometrics; LIHC cis rs9296092 0.500 rs35150558 chr6:33519612 T/A cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs60871478 1.000 rs62432242 chr7:797715 G/A cg05535760 chr7:792225 HEATR2 0.79 11.14 0.52 8.15e-25 Cerebrospinal P-tau181p levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13129888 chr1:28415099 EYA3 0.43 6.05 0.31 3.85e-9 Cognitive function; LIHC cis rs1451375 0.583 rs7776816 chr7:50583534 G/A cg14593290 chr7:50529359 DDC 0.61 9.74 0.47 5.81e-20 Malaria; LIHC cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg09222892 chr1:25734099 RHCE -0.46 -8.41 -0.41 1.13e-15 Erythrocyte sedimentation rate; LIHC cis rs4888262 0.526 rs4887776 chr16:74635632 A/G cg01733217 chr16:74700730 RFWD3 0.83 16.0 0.65 2.01e-43 Testicular germ cell tumor; LIHC cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.87 0.3 1.04e-8 Menopause (age at onset); LIHC cis rs3096299 0.933 rs28608022 chr16:89454292 C/T cg06640241 chr16:89574553 SPG7 0.65 10.52 0.49 1.27e-22 Multiple myeloma (IgH translocation); LIHC cis rs1707322 0.721 rs10789470 chr1:46158331 T/G cg03146154 chr1:46216737 IPP 0.6 10.26 0.49 1.04e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs60871478 0.947 rs62432862 chr7:807719 G/C cg04727924 chr7:799746 HEATR2 -0.6 -8.7 -0.43 1.37e-16 Cerebrospinal P-tau181p levels; LIHC cis rs713477 0.654 rs11158040 chr14:55914607 T/C cg13175173 chr14:55914753 NA -0.31 -7.19 -0.36 4.03e-12 Pediatric bone mineral content (femoral neck); LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC trans rs6951245 0.786 rs77943789 chr7:1140158 C/T cg13565492 chr6:43139072 SRF -0.8 -6.33 -0.32 7.5e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10791097 0.694 rs2155750 chr11:130751261 A/C cg22079354 chr11:130786696 SNX19 0.43 6.19 0.32 1.73e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6430585 0.583 rs3769001 chr2:136626078 A/G cg15123519 chr2:136567270 LCT -0.37 -5.82 -0.3 1.33e-8 Corneal structure; LIHC cis rs6089584 1.000 rs3787424 chr20:60559219 G/A cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.07e-8 Body mass index; LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.65 0.62 4.71e-38 Prudent dietary pattern; LIHC cis rs13161895 1.000 rs12654148 chr5:179438920 T/A cg02702477 chr5:179499311 RNF130 -0.74 -10.27 -0.49 9.85e-22 LDL cholesterol; LIHC cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.84 0.69 8.72e-51 Gut microbiome composition (summer); LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg03395511 chr6:291903 DUSP22 -0.5 -6.54 -0.33 2.2e-10 Menopause (age at onset); LIHC cis rs8078723 0.677 rs11658328 chr17:38149236 T/C cg17467752 chr17:38218738 THRA -0.59 -10.14 -0.48 2.72e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs644799 0.965 rs11021317 chr11:95517576 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.7 10.17 0.48 2.13e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1816752 0.905 rs7317850 chr13:24994037 C/G cg22771759 chr13:24902376 NA 0.33 6.57 0.33 1.87e-10 Obesity-related traits; LIHC cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg11764359 chr7:65958608 NA -0.58 -6.08 -0.31 3.14e-9 Diabetic kidney disease; LIHC cis rs72627123 0.867 rs8020310 chr14:74494437 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.86 0.3 1.06e-8 Morning vs. evening chronotype; LIHC trans rs875971 0.508 rs10253883 chr7:66061138 T/C cg26939375 chr7:64535504 NA -0.43 -7.32 -0.37 1.77e-12 Aortic root size; LIHC cis rs1348850 0.526 rs59972556 chr2:178399561 A/G cg27490568 chr2:178487706 NA 0.97 10.96 0.51 3.66e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7666738 0.710 rs7674407 chr4:98838522 A/G cg05340658 chr4:99064831 C4orf37 0.63 11.57 0.53 2.45e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs425277 0.606 rs262663 chr1:2084598 T/C cg03732007 chr1:2071316 PRKCZ 0.36 6.19 0.32 1.75e-9 Height; LIHC trans rs4843747 0.749 rs13333619 chr16:88072076 C/T cg09572067 chr16:29127029 RRN3P2 0.62 9.66 0.46 1.1e-19 Menopause (age at onset); LIHC cis rs13217239 0.646 rs4583981 chr6:26992023 G/T cg12292205 chr6:26970375 C6orf41 0.45 7.77 0.39 9.2e-14 Schizophrenia; LIHC cis rs7914558 0.966 rs10786719 chr10:104637992 C/T cg15744005 chr10:104629667 AS3MT 0.38 8.44 0.42 8.93e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs7613875 0.620 rs17657688 chr3:50033228 C/T cg24110177 chr3:50126178 RBM5 0.54 8.63 0.42 2.32e-16 Body mass index; LIHC cis rs8017423 0.967 rs4904658 chr14:90721640 C/T cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 2.97e-9 Mortality in heart failure; LIHC cis rs765787 0.530 rs4775844 chr15:45542048 T/C cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC cis rs1843834 0.716 rs6716600 chr2:225481991 A/T cg22455342 chr2:225449267 CUL3 0.45 6.07 0.31 3.33e-9 IgE levels in asthmatics (D.p. specific); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12196473 chr3:99536614 MIR548G;C3orf26 0.43 6.3 0.32 9.05e-10 Pancreatic cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg18954051 chr12:66554863 TMBIM4 0.45 6.53 0.33 2.33e-10 Hepatitis; LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.64 0.46 1.3e-19 Height; LIHC cis rs1552244 0.572 rs41464050 chr3:10158393 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.74 7.68 0.38 1.74e-13 Alzheimer's disease; LIHC cis rs7647973 0.710 rs9869120 chr3:49624065 T/C cg03060546 chr3:49711283 APEH 0.62 6.97 0.35 1.65e-11 Menarche (age at onset); LIHC cis rs17401966 0.838 rs4846212 chr1:10370312 T/C cg15208524 chr1:10270712 KIF1B 0.38 5.85 0.3 1.15e-8 Hepatocellular carcinoma; LIHC cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg11764359 chr7:65958608 NA -0.58 -6.04 -0.31 3.97e-9 Diabetic kidney disease; LIHC cis rs6754311 0.512 rs12998387 chr2:136507039 A/G cg25344623 chr2:136566232 LCT 0.44 8.82 0.43 5.85e-17 Mosquito bite size; LIHC cis rs55665837 0.520 rs10766189 chr11:14733923 G/A cg25251204 chr11:14927456 NA 0.41 5.87 0.3 1.03e-8 Vitamin D levels; LIHC cis rs6782228 0.606 rs58977394 chr3:128337917 C/T cg16766828 chr3:128327626 NA -0.41 -6.46 -0.33 3.69e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs9814567 0.806 rs6799543 chr3:134216139 G/T cg06541857 chr3:134203789 ANAPC13;CEP63 -0.39 -5.78 -0.3 1.73e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.52 -0.56 7.42e-30 Alzheimer's disease; LIHC cis rs9914988 0.887 rs9895625 chr17:27108516 A/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7085104 0.700 rs10786712 chr10:104596396 A/G cg15744005 chr10:104629667 AS3MT 0.39 8.94 0.44 2.53e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC trans rs1005277 0.540 rs2145487 chr10:38010077 A/G cg23533926 chr12:111358616 MYL2 -0.32 -6.23 -0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7945705 0.869 rs11042154 chr11:9029700 A/G cg12365402 chr11:9010492 NRIP3 -0.31 -7.87 -0.39 4.67e-14 Hemoglobin concentration; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg26429905 chr20:35917924 MANBAL -0.55 -6.05 -0.31 3.88e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg02990361 chr1:107599529 PRMT6 -0.58 -9.49 -0.46 4.01e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs903552 1.000 rs12719737 chr15:101999126 C/G cg19295451 chr15:102010161 PCSK6 -0.43 -6.04 -0.31 4.03e-9 Diabetic kidney disease; LIHC cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg18357526 chr6:26021779 HIST1H4A 0.96 13.83 0.6 7.62e-35 Intelligence (multi-trait analysis); LIHC cis rs56011263 0.687 rs4690187 chr4:703813 C/T cg20735989 chr4:730612 PCGF3 -0.66 -8.72 -0.43 1.23e-16 White blood cell count; LIHC cis rs797680 0.856 rs687394 chr1:93713917 G/A cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.89 0.3 9.29e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg03188948 chr7:1209495 NA 0.46 6.52 0.33 2.49e-10 Longevity;Endometriosis; LIHC cis rs8067354 0.527 rs1292039 chr17:57974913 A/T cg02344993 chr17:57696989 CLTC 0.67 10.55 0.5 1.04e-22 Hemoglobin concentration; LIHC trans rs35110281 0.627 rs1836855 chr21:44965414 C/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.5 6.87 0.35 3.01e-11 Mean corpuscular volume; LIHC cis rs7095944 0.644 rs4962694 chr10:126436717 G/T cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.87e-10 Asthma; LIHC cis rs7089973 0.624 rs10885614 chr10:116609098 C/T cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2302190 0.882 rs1974586 chr17:56640731 C/T cg05425664 chr17:57184151 TRIM37 -0.46 -5.79 -0.3 1.58e-8 Vitamin D levels; LIHC cis rs9733 0.596 rs56058687 chr1:150635066 C/T cg17724175 chr1:150552817 MCL1 0.48 9.54 0.46 2.83e-19 Tonsillectomy; LIHC cis rs9902453 0.765 rs2259857 chr17:28097780 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.75 -0.6 1.56e-34 Coffee consumption (cups per day); LIHC cis rs2230307 0.505 rs482873 chr1:100589757 C/T cg24955406 chr1:100503596 HIAT1 -0.59 -5.8 -0.3 1.53e-8 Carotid intima media thickness; LIHC cis rs798554 0.600 rs2679259 chr7:2885322 C/G cg04166393 chr7:2884313 GNA12 0.37 6.06 0.31 3.62e-9 Height; LIHC cis rs1707322 0.896 rs946528 chr1:46485562 C/T cg03146154 chr1:46216737 IPP -0.48 -7.85 -0.39 5.49e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11583043 1.000 rs12567858 chr1:101517688 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.51 6.15 0.32 2.11e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs12479064 0.724 rs3792150 chr2:100041849 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -6.94 -0.35 1.99e-11 Chronic sinus infection; LIHC cis rs7520050 0.966 rs4660317 chr1:46326226 G/A cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs10504229 0.724 rs72649117 chr8:58037639 A/G cg02290350 chr8:58132656 NA 0.31 7.15 0.36 5.41e-12 Developmental language disorder (linguistic errors); LIHC cis rs6840360 1.000 rs6535813 chr4:152599652 A/T cg22705602 chr4:152727874 NA -0.31 -6.53 -0.33 2.38e-10 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs977652 chr3:40479169 A/G cg13409248 chr3:40428643 ENTPD3 0.42 7.09 0.36 7.87e-12 Renal cell carcinoma; LIHC cis rs11105298 0.891 rs12369195 chr12:89934972 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.29 -0.37 2.22e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7552404 1.000 rs4949872 chr1:76131392 C/G cg10523679 chr1:76189770 ACADM 0.64 8.72 0.43 1.23e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg11861562 chr11:117069780 TAGLN 0.48 7.89 0.39 4.2e-14 Blood protein levels; LIHC cis rs875971 0.862 rs1968126 chr7:66057004 A/G cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.26e-34 Aortic root size; LIHC trans rs10213084 0.915 rs10212988 chr4:147501000 A/G cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs595982 0.527 rs12151238 chr19:49368613 T/C cg21252483 chr19:49399788 TULP2 -0.92 -10.19 -0.48 1.83e-21 Red cell distribution width; LIHC cis rs7914558 0.933 rs12763665 chr10:104653717 G/A cg15744005 chr10:104629667 AS3MT -0.41 -9.29 -0.45 1.79e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg20011983 chr2:74347215 NA -0.39 -5.74 -0.3 2.11e-8 Gestational age at birth (maternal effect); LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg18279126 chr7:2041391 MAD1L1 -0.39 -6.72 -0.34 7.48e-11 Bipolar disorder and schizophrenia; LIHC trans rs3960554 1.000 rs2097947 chr7:75836382 A/T cg19862616 chr7:65841803 NCRNA00174 0.62 9.51 0.46 3.57e-19 Eotaxin levels; LIHC cis rs7131987 0.903 rs10843367 chr12:29408380 G/A cg21522988 chr12:29376872 FAR2 0.28 6.22 0.32 1.45e-9 QT interval; LIHC cis rs12478296 0.681 rs56357900 chr2:243033966 A/C cg06360820 chr2:242988706 NA -0.82 -11.43 -0.53 7.73e-26 Obesity-related traits; LIHC cis rs2806561 1.000 rs1757044 chr1:23515631 T/C cg19743168 chr1:23544995 NA 0.4 7.67 0.38 1.8e-13 Height; LIHC cis rs9814567 0.806 rs4955534 chr3:134319723 T/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12286929 0.609 rs11602686 chr11:115100638 G/A cg04055981 chr11:115044050 NA 0.43 6.23 0.32 1.4e-9 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs709400 0.628 rs10141120 chr14:103923008 T/C cg26031613 chr14:104095156 KLC1 0.72 9.71 0.46 7.42e-20 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20840002 chr11:105924441 KBTBD3 0.34 6.5 0.33 2.92e-10 Cognitive function; LIHC cis rs1065852 0.510 rs5758666 chr22:42632833 G/A cg00645731 chr22:42541494 CYP2D7P1 0.38 6.41 0.33 4.72e-10 Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels); LIHC cis rs2834256 0.517 rs7280365 chr21:34952583 G/C cg14850771 chr21:34775459 IFNGR2 0.45 7.09 0.36 7.93e-12 Red cell distribution width; LIHC cis rs7772486 0.875 rs2224120 chr6:146343280 A/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.1 -0.31 2.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1865760 0.929 rs12195653 chr6:25958621 A/G cg12310025 chr6:25882481 NA -0.39 -5.85 -0.3 1.15e-8 Height; LIHC cis rs9733 0.596 rs11803569 chr1:150664077 C/T cg18016565 chr1:150552671 MCL1 0.59 11.56 0.53 2.57e-26 Tonsillectomy; LIHC cis rs7520050 0.966 rs6669522 chr1:46397941 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg22633049 chr21:46681294 NA -0.37 -6.4 -0.33 5.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1008375 1.000 rs10939738 chr4:17604295 G/C cg02297831 chr4:17616191 MED28 0.44 6.81 0.35 4.51e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6088590 1.000 rs2378256 chr20:33292127 G/C cg24642439 chr20:33292090 TP53INP2 0.81 11.71 0.54 7.16e-27 Coronary artery disease; LIHC cis rs1034435 0.755 rs713923 chr22:48891519 C/T cg05992904 chr22:48892994 FAM19A5 0.45 9.11 0.44 6.97e-18 Late-onset Alzheimer's disease; LIHC cis rs597539 0.652 rs611046 chr11:68631704 A/G cg04772025 chr11:68637568 NA 0.43 5.73 0.3 2.21e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7617773 0.780 rs7632297 chr3:48348163 A/C cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg20607798 chr8:58055168 NA 0.6 7.16 0.36 4.89e-12 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.867 rs13227219 chr7:65844062 T/A cg11764359 chr7:65958608 NA 0.91 16.72 0.67 2.66e-46 Aortic root size; LIHC cis rs2153535 0.580 rs2327058 chr6:8447018 C/T cg07606381 chr6:8435919 SLC35B3 0.78 11.53 0.53 3.21e-26 Motion sickness; LIHC cis rs12134245 0.776 rs12125947 chr1:91990487 T/C cg07090678 chr1:91966139 CDC7 0.53 7.26 0.37 2.61e-12 Breast cancer; LIHC trans rs75804782 0.641 rs72987304 chr2:239345532 C/T cg01134436 chr17:81009848 B3GNTL1 0.84 7.19 0.36 4.11e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg13866156 chr1:1669148 SLC35E2 -0.68 -12.8 -0.57 6.55e-31 Body mass index; LIHC cis rs7249142 0.549 rs12975253 chr19:19279745 A/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.23 -0.32 1.37e-9 IgG glycosylation; LIHC cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg21724239 chr8:58056113 NA 0.61 7.35 0.37 1.45e-12 Developmental language disorder (linguistic errors); LIHC cis rs11229555 0.598 rs12276438 chr11:58185419 G/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9818758 0.556 rs9880309 chr3:49304329 G/C cg06212747 chr3:49208901 KLHDC8B -0.67 -5.88 -0.3 9.85e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs55665837 0.701 rs12787709 chr11:14639257 G/A cg25251204 chr11:14927456 NA 0.44 5.89 0.3 9.34e-9 Vitamin D levels; LIHC cis rs7927771 0.832 rs935914 chr11:47387599 C/T cg20135002 chr11:47629003 NA 0.5 8.61 0.42 2.76e-16 Subjective well-being; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg06873352 chr17:61820015 STRADA 0.51 7.68 0.38 1.69e-13 Height; LIHC cis rs9649213 0.593 rs13246868 chr7:97986453 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.24e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs13108904 0.846 rs4974574 chr4:1224811 A/G cg05665937 chr4:1216051 CTBP1 0.48 6.59 0.34 1.62e-10 Obesity-related traits; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg02279591 chr5:94989328 RFESD -0.26 -6.38 -0.33 5.68e-10 Calcium levels; LIHC trans rs7939886 0.764 rs79601668 chr11:55753767 G/C cg15704280 chr7:45808275 SEPT13 0.64 6.11 0.31 2.72e-9 Myopia (pathological); LIHC cis rs3106136 0.546 rs2664880 chr4:95144177 T/A cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.32 -0.45 1.52e-18 Capecitabine sensitivity; LIHC cis rs4728302 0.838 rs13231095 chr7:133604436 A/G cg10665199 chr7:133106180 EXOC4 0.39 6.81 0.35 4.51e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs11711311 1.000 rs9830978 chr3:113455940 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.05 -0.36 9.72e-12 IgG glycosylation; LIHC cis rs2637266 0.935 rs1866891 chr10:78396941 C/A cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs7772486 0.875 rs865913 chr6:146308874 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.3 -0.32 9.41e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.645 rs2140602 chr11:50022800 G/C cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs921968 0.643 rs500317 chr2:219432953 G/C cg18887096 chr2:219472410 PLCD4 0.35 6.26 0.32 1.13e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.47 0.37 6.91e-13 Prudent dietary pattern; LIHC cis rs796364 0.806 rs10931889 chr2:201101900 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.8 -8.98 -0.44 1.8e-17 Schizophrenia; LIHC trans rs1814175 0.817 rs1615305 chr11:49895222 T/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs4072980 0.524 rs28442147 chr1:38395410 T/A cg12658694 chr1:38397304 INPP5B 0.41 6.03 0.31 4.22e-9 Coronary artery disease; LIHC cis rs12474201 0.963 rs11676737 chr2:46929873 T/C cg06386533 chr2:46925753 SOCS5 0.74 8.23 0.41 3.88e-15 Height; LIHC cis rs6977660 0.619 rs2158379 chr7:19783977 A/G cg07541023 chr7:19748670 TWISTNB 0.4 5.95 0.31 6.56e-9 Thyroid stimulating hormone; LIHC cis rs17685 0.753 rs10952840 chr7:75772878 C/T cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs7617989 chr3:40512463 A/G cg24209194 chr3:40518798 ZNF619 -0.54 -8.06 -0.4 1.26e-14 Renal cell carcinoma; LIHC cis rs12477438 0.798 rs6542849 chr2:99578493 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.06 -0.51 1.7e-24 Chronic sinus infection; LIHC trans rs10506458 0.915 rs12424908 chr12:63402364 G/A cg22491629 chr6:157744540 C6orf35 -0.6 -10.9 -0.51 6.06e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg13395646 chr4:1353034 KIAA1530 -0.66 -9.5 -0.46 3.65e-19 Obesity-related traits; LIHC cis rs1552244 0.882 rs36006511 chr3:10054191 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.59 0.5 7.6e-23 Alzheimer's disease; LIHC cis rs3743104 0.510 rs16973303 chr15:33020928 A/C cg07179000 chr15:33023586 GREM1 -0.51 -8.1 -0.4 9.53e-15 Hypospadias; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg27187586 chr4:83932193 LIN54 -0.32 -6.44 -0.33 3.96e-10 Oropharynx cancer; LIHC cis rs7208859 0.673 rs11656462 chr17:29160700 G/A cg14067834 chr17:29058358 SUZ12P 0.63 6.12 0.31 2.61e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6840360 0.593 rs10222925 chr4:152690215 A/G cg22705602 chr4:152727874 NA -0.4 -8.47 -0.42 7.54e-16 Intelligence (multi-trait analysis); LIHC trans rs7618501 1.000 rs7648987 chr3:49868455 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.79 14.38 0.61 5.17e-37 Intelligence (multi-trait analysis); LIHC cis rs4713118 0.513 rs156734 chr6:28007357 A/C cg23485639 chr6:28045615 ZNF165 0.38 5.87 0.3 1.02e-8 Parkinson's disease; LIHC cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg18357526 chr6:26021779 HIST1H4A 0.42 6.33 0.32 7.66e-10 Height; LIHC cis rs6504663 1.000 rs6504661 chr17:48580126 A/T cg00901687 chr17:48585270 MYCBPAP -0.53 -7.6 -0.38 2.92e-13 Visceral fat; LIHC cis rs9329289 0.590 rs11251295 chr10:2563183 C/T cg15501526 chr10:2543763 NA 0.22 5.94 0.31 7.09e-9 Age-related hearing impairment; LIHC cis rs9868809 0.505 rs11706203 chr3:48746239 T/A cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.53e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs7572733 0.534 rs4850813 chr2:198775982 C/T cg03934865 chr2:198174659 NA -0.46 -6.7 -0.34 8.85e-11 Dermatomyositis; LIHC cis rs1059312 0.500 rs12303338 chr12:129276641 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.51 7.7 0.38 1.49e-13 Systemic lupus erythematosus; LIHC cis rs910316 0.789 rs12894419 chr14:75471802 C/T cg11812906 chr14:75593930 NEK9 0.74 13.67 0.59 3.08e-34 Height; LIHC cis rs1941023 0.503 rs4528348 chr11:60129505 C/G cg08716584 chr11:60157161 MS4A7 -0.36 -8.22 -0.41 4.14e-15 Congenital heart disease (maternal effect); LIHC cis rs10088262 0.629 rs7015861 chr8:124795613 C/T cg20713898 chr8:124780851 FAM91A1 -0.52 -7.07 -0.36 8.71e-12 Pancreatic cancer; LIHC cis rs2569991 0.636 rs2600222 chr3:12937617 C/G cg22481960 chr3:13008800 IQSEC1 -0.43 -7.45 -0.37 7.57e-13 Periodontitis (DPAL); LIHC cis rs6430585 0.528 rs499483 chr2:136652524 G/A cg07169764 chr2:136633963 MCM6 1.32 21.74 0.76 2.04e-66 Corneal structure; LIHC cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg02359409 chr6:42947317 PEX6 -0.41 -5.91 -0.3 8.38e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.17 -0.32 1.97e-9 Diastolic blood pressure; LIHC cis rs1401999 1.000 rs2872249 chr3:183636273 T/A cg05044414 chr3:183734942 ABCC5 0.34 5.91 0.3 8.16e-9 Anterior chamber depth; LIHC cis rs9648428 0.515 rs17172276 chr7:36202416 A/G cg14708893 chr7:36124863 NA -0.41 -6.18 -0.32 1.79e-9 Obesity-related traits; LIHC cis rs7772486 0.846 rs1474871 chr6:146406294 G/A cg05347473 chr6:146136440 FBXO30 0.35 5.77 0.3 1.76e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs950776 0.518 rs12910978 chr15:78810017 A/G cg06917634 chr15:78832804 PSMA4 0.9 13.21 0.58 1.73e-32 Sudden cardiac arrest; LIHC cis rs4819052 0.959 rs9976074 chr21:46655638 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 8.21 0.41 4.6e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6918586 0.681 rs198831 chr6:26116996 T/C cg18357526 chr6:26021779 HIST1H4A -0.56 -8.25 -0.41 3.57e-15 Schizophrenia; LIHC cis rs3857067 0.806 rs17374832 chr4:95114394 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs3770081 0.826 rs76780449 chr2:86222811 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.78 -5.91 -0.3 8.06e-9 Facial emotion recognition (sad faces); LIHC cis rs17818399 0.926 rs1824050 chr2:46839477 T/C cg02822958 chr2:46747628 ATP6V1E2 0.45 6.68 0.34 9.75e-11 Height; LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg24693881 chr1:107596107 NA 0.52 8.99 0.44 1.77e-17 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7172677 0.768 rs12148425 chr15:75354972 T/C cg09165964 chr15:75287851 SCAMP5 0.48 6.93 0.35 2.12e-11 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs10876993 0.893 rs1678504 chr12:58085498 G/C cg15848620 chr12:58087721 OS9 -0.57 -7.55 -0.38 4.1e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs4788570 0.543 rs4788820 chr16:71660115 G/C cg06353428 chr16:71660113 MARVELD3 1.46 15.47 0.64 2.73e-41 Intelligence (multi-trait analysis); LIHC cis rs748404 0.631 rs560191 chr15:43767774 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.3 0.37 2.01e-12 Lung cancer; LIHC trans rs2739330 0.627 rs9608219 chr22:24274119 G/C cg06437703 chr8:37914619 EIF4EBP1 -0.6 -9.26 -0.45 2.4e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1204798 0.589 rs10223646 chr6:116617399 C/T cg23214565 chr6:116600728 DSE;TSPYL1 -0.42 -6.2 -0.32 1.63e-9 Dental caries; LIHC cis rs4407350 0.837 rs4823326 chr22:44908678 C/T cg04154583 chr22:44889756 LDOC1L 0.29 5.75 0.3 2.02e-8 Intelligence (multi-trait analysis); LIHC cis rs75887402 0.744 rs4836002 chr5:122676161 A/G cg27033705 chr5:122759302 CEP120 -0.8 -5.71 -0.3 2.46e-8 Breast cancer; LIHC cis rs752092 0.894 rs8036083 chr15:101767822 T/G cg25114630 chr15:101792522 CHSY1 0.55 6.85 0.35 3.37e-11 Corneal structure; LIHC cis rs853679 0.517 rs9368554 chr6:28082711 T/C cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs9527 0.830 rs11191440 chr10:104641511 G/A cg15744005 chr10:104629667 AS3MT -0.34 -6.73 -0.34 7.2e-11 Arsenic metabolism; LIHC cis rs7512552 0.809 rs2794679 chr1:150324857 G/A cg15654264 chr1:150340011 RPRD2 0.69 11.33 0.52 1.78e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs17106184 1.000 rs11205788 chr1:51363096 G/A cg07174182 chr1:51127561 FAF1 -0.75 -7.7 -0.38 1.44e-13 Type 2 diabetes; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07777156 chr17:22022000 NA 0.5 6.45 0.33 3.73e-10 Hepatitis; LIHC cis rs6933660 0.720 rs6936936 chr6:151753395 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.61 10.11 0.48 3.46e-21 Menarche (age at onset); LIHC cis rs9486719 0.857 rs2983897 chr6:97033780 C/T cg06623918 chr6:96969491 KIAA0776 -0.64 -7.66 -0.38 1.87e-13 Migraine;Coronary artery disease; LIHC cis rs875971 0.830 rs587360 chr7:65522698 C/A cg11764359 chr7:65958608 NA 0.83 13.84 0.6 6.62e-35 Aortic root size; LIHC cis rs17102884 0.541 rs8004430 chr14:75171683 C/T cg08847533 chr14:75593920 NEK9 0.45 7.0 0.35 1.35e-11 Neuroticism; LIHC cis rs56104184 0.723 rs73063522 chr19:49408358 C/G cg15549821 chr19:49342101 PLEKHA4 -0.65 -6.17 -0.32 1.9e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg11645453 chr3:52864694 ITIH4 0.22 5.96 0.31 6.39e-9 Bipolar disorder; LIHC cis rs1564271 1.000 rs1564271 chr10:27011112 G/A cg13837822 chr10:26931731 LOC731789 0.34 6.08 0.31 3.15e-9 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs4561483 0.831 rs2075158 chr16:11945231 T/C cg08843971 chr16:11963173 GSPT1 0.32 6.35 0.32 6.83e-10 Testicular germ cell tumor; LIHC cis rs8078723 0.714 rs12940405 chr17:38143768 C/T cg17467752 chr17:38218738 THRA -0.59 -10.13 -0.48 2.93e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg21448741 chr8:58168803 NA 0.35 6.09 0.31 3.02e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg11764359 chr7:65958608 NA -0.58 -5.98 -0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs11955398 0.563 rs4700385 chr5:60032599 G/A cg02684056 chr5:59996105 DEPDC1B -0.4 -5.71 -0.3 2.46e-8 Intelligence (multi-trait analysis); LIHC cis rs4474465 0.850 rs4559714 chr11:78257302 C/T cg27205649 chr11:78285834 NARS2 0.38 5.86 0.3 1.09e-8 Alzheimer's disease (survival time); LIHC cis rs9612 0.664 rs164069 chr19:44260199 T/C cg08581076 chr19:44259116 C19orf61 0.61 8.01 0.4 1.76e-14 Exhaled nitric oxide output; LIHC cis rs3859192 0.561 rs12453343 chr17:38181176 C/A cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.89 0.65 5.71e-43 White blood cell count; LIHC cis rs2549003 1.000 rs2549005 chr5:131827191 C/T cg02551604 chr5:131831745 NA -0.5 -7.01 -0.35 1.27e-11 Asthma (sex interaction); LIHC cis rs7940866 0.838 rs1991898 chr11:130801786 C/G cg12179176 chr11:130786555 SNX19 -0.66 -9.88 -0.47 2e-20 Schizophrenia; LIHC cis rs3106136 0.678 rs6532485 chr4:95297120 C/T cg11021082 chr4:95130006 SMARCAD1 0.36 6.14 0.32 2.27e-9 Capecitabine sensitivity; LIHC cis rs17095355 1.000 rs55728195 chr10:111715599 G/A cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.76 -0.3 1.83e-8 Biliary atresia; LIHC cis rs637571 0.522 rs491973 chr11:65727301 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.12 0.44 6.49e-18 Eosinophil percentage of white cells; LIHC cis rs3106136 0.967 rs66581998 chr4:95196901 T/C cg11021082 chr4:95130006 SMARCAD1 -0.45 -8.16 -0.4 6.37e-15 Capecitabine sensitivity; LIHC cis rs2346177 0.874 rs35462976 chr2:46649049 A/G cg02822958 chr2:46747628 ATP6V1E2 0.41 6.38 0.33 5.6e-10 HDL cholesterol; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg20638626 chr8:12523153 NA 0.54 6.85 0.35 3.4e-11 Hepatitis; LIHC cis rs8013055 0.846 rs12717698 chr14:105979015 G/A cg19700328 chr14:106028568 NA -0.37 -7.81 -0.39 7.04e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs13191362 0.507 rs2849525 chr6:163126652 A/C cg21926612 chr6:163149169 PACRG;PARK2 -0.53 -6.03 -0.31 4.15e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11626933 1.000 rs11626933 chr14:90754311 A/G cg04374321 chr14:90722782 PSMC1 0.47 6.53 0.33 2.34e-10 Gut microbiota (bacterial taxa); LIHC cis rs7208859 0.623 rs7223209 chr17:29107220 C/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs77633900 0.614 rs2468120 chr15:76909975 G/A cg21673338 chr15:77095150 SCAPER -0.49 -7.21 -0.36 3.68e-12 Non-glioblastoma glioma;Glioma; LIHC trans rs561341 0.714 rs7218466 chr17:30263314 A/G cg20587970 chr11:113659929 NA -0.58 -6.79 -0.34 4.87e-11 Hip circumference adjusted for BMI; LIHC cis rs655641 0.834 rs2458496 chr11:85718816 C/G cg09030501 chr11:85779252 PICALM -0.52 -6.14 -0.32 2.23e-9 Platelet count; LIHC cis rs8060686 0.623 rs2301814 chr16:68105171 C/G cg05110241 chr16:68378359 PRMT7 -0.5 -6.11 -0.31 2.75e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs11031096 0.678 rs61899754 chr11:4201312 A/T cg18678763 chr11:4115507 RRM1 -0.41 -5.94 -0.31 6.88e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2842992 0.789 rs2277072 chr6:160182845 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.56 0.42 3.83e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs1401999 1.000 rs13317532 chr3:183641669 G/C cg01324343 chr3:183735012 ABCC5 0.74 12.06 0.55 3.69e-28 Anterior chamber depth; LIHC cis rs3784262 1.000 rs11855259 chr15:58249377 C/G cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.35 -0.32 6.94e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg14983838 chr19:29218262 NA 0.48 7.85 0.39 5.31e-14 Methadone dose in opioid dependence; LIHC cis rs8084351 0.569 rs16956411 chr18:50775428 A/G cg24270629 chr18:50823537 DCC -0.48 -7.14 -0.36 5.59e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg00815214 chr21:47717953 NA 0.34 5.72 0.3 2.37e-8 Testicular germ cell tumor; LIHC cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg14393609 chr7:65229607 NA 0.45 6.59 0.34 1.63e-10 Aortic root size; LIHC cis rs10883723 0.773 rs11191313 chr10:104278618 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 9.93 0.47 1.38e-20 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2569991 1.000 rs2569991 chr3:12923197 C/A cg22481960 chr3:13008800 IQSEC1 -0.38 -6.61 -0.34 1.45e-10 Periodontitis (DPAL); LIHC cis rs250677 0.687 rs250667 chr5:148455134 A/G cg12140854 chr5:148520817 ABLIM3 0.45 6.16 0.32 2.01e-9 Breast cancer; LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.5 -6.2 -0.32 1.66e-9 Diastolic blood pressure; LIHC trans rs7618501 0.633 rs6772095 chr3:49978069 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.57 9.36 0.45 1.1e-18 Intelligence (multi-trait analysis); LIHC cis rs10489202 1.000 rs12727036 chr1:167972147 A/G cg24449463 chr1:168025552 DCAF6 -0.52 -6.5 -0.33 2.9e-10 Schizophrenia; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg22903471 chr2:27725779 GCKR -0.49 -8.41 -0.41 1.12e-15 Total body bone mineral density; LIHC cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg14983838 chr19:29218262 NA 0.48 7.46 0.37 7.27e-13 Methadone dose in opioid dependence; LIHC cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg18230493 chr5:56204884 C5orf35 -0.47 -6.54 -0.33 2.25e-10 Initial pursuit acceleration; LIHC cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.4 0.45 8.18e-19 Platelet count; LIHC cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg03806693 chr22:41940476 POLR3H -1.04 -12.81 -0.57 5.96e-31 Vitiligo; LIHC cis rs2251381 0.750 rs2255055 chr21:30537045 C/T cg08807101 chr21:30365312 RNF160 0.77 10.93 0.51 4.74e-24 Selective IgA deficiency; LIHC cis rs6570726 0.935 rs421268 chr6:145845558 A/T cg23711669 chr6:146136114 FBXO30 0.56 10.02 0.48 6.91e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs9641123 0.639 rs2677079 chr7:93256401 C/G cg09745688 chr16:2908918 PRSS22 -0.39 -6.85 -0.35 3.42e-11 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs7220401 0.521 rs11080105 chr17:27904711 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.49 7.31 0.37 1.86e-12 Coronary artery disease; LIHC cis rs11792861 0.781 rs838835 chr9:111758590 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.62 -8.69 -0.43 1.5e-16 Menarche (age at onset); LIHC cis rs2842992 0.789 rs2475566 chr6:160148741 C/T cg11366901 chr6:160182831 ACAT2 0.96 16.24 0.66 2.23e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.99 -0.4 2.13e-14 Lymphocyte counts; LIHC cis rs5769765 1.000 rs2295408 chr22:50261051 A/G cg02269571 chr22:50332266 NA 0.61 8.63 0.42 2.37e-16 Schizophrenia; LIHC cis rs10751667 0.621 rs7394862 chr11:927500 T/C cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs7945705 0.935 rs11042102 chr11:8882164 C/T cg12365402 chr11:9010492 NRIP3 0.29 7.4 0.37 1.07e-12 Hemoglobin concentration; LIHC cis rs10489202 0.657 rs3767479 chr1:168069840 C/A cg24449463 chr1:168025552 DCAF6 -0.49 -6.66 -0.34 1.1e-10 Schizophrenia; LIHC cis rs10791097 0.748 rs2282579 chr11:130735482 C/T cg22079354 chr11:130786696 SNX19 0.42 6.08 0.31 3.18e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6750047 0.605 rs2121260 chr2:38268763 T/G cg07380506 chr2:38303506 CYP1B1 0.58 7.29 0.37 2.22e-12 Cutaneous malignant melanoma;Melanoma; LIHC cis rs11166927 0.548 rs2100803 chr8:140839371 A/C cg16909799 chr8:140841666 TRAPPC9 -0.5 -8.01 -0.4 1.81e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs7191868 1 rs7191868 chr16:536090 G/C cg06259664 chr16:537672 RAB11FIP3 0.52 6.12 0.31 2.5e-9 Platelet distribution width; LIHC cis rs208520 0.690 rs12201156 chr6:66720874 G/T cg07460842 chr6:66804631 NA 0.75 8.71 0.43 1.33e-16 Exhaled nitric oxide output; LIHC trans rs7618501 0.966 rs13085679 chr3:49869631 G/A cg21582582 chr3:182698605 DCUN1D1 0.54 7.01 0.35 1.24e-11 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.601 rs4140585 chr6:8503298 T/A cg21535247 chr6:8435926 SLC35B3 0.6 7.94 0.39 2.95e-14 Motion sickness; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg14004847 chr7:1930337 MAD1L1 -0.46 -6.78 -0.34 5.13e-11 Bipolar disorder and schizophrenia; LIHC cis rs1670533 0.615 rs59985183 chr4:1087171 G/T cg27284194 chr4:1044797 NA 0.59 8.93 0.43 2.6e-17 Recombination rate (females); LIHC trans rs61931739 0.517 rs1586409 chr12:34046614 C/A cg26384229 chr12:38710491 ALG10B 0.47 6.61 0.34 1.43e-10 Morning vs. evening chronotype; LIHC cis rs2228479 0.850 rs76075456 chr16:89834270 T/C cg06558623 chr16:89946397 TCF25 0.85 11.71 0.53 7.62e-27 Skin colour saturation; LIHC cis rs7512552 0.839 rs11577600 chr1:150407443 G/A cg15654264 chr1:150340011 RPRD2 0.68 11.21 0.52 4.66e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs7246657 0.943 rs9304566 chr19:37845504 T/C cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs17685 0.712 rs4552844 chr7:75718095 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9486719 1.000 rs9400016 chr6:96940883 G/T cg06623918 chr6:96969491 KIAA0776 -0.63 -6.52 -0.33 2.54e-10 Migraine;Coronary artery disease; LIHC cis rs595982 0.546 rs12461075 chr19:49399821 G/A cg21252483 chr19:49399788 TULP2 -0.6 -9.41 -0.45 7.76e-19 Red cell distribution width; LIHC cis rs7208859 0.673 rs11658435 chr17:29228561 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6466055 0.867 rs10241415 chr7:104948076 A/G cg04380332 chr7:105027541 SRPK2 0.37 6.88 0.35 2.88e-11 Schizophrenia; LIHC cis rs4759375 1.000 rs1109560 chr12:123757905 C/A cg00376283 chr12:123451042 ABCB9 -0.49 -6.26 -0.32 1.17e-9 HDL cholesterol; LIHC cis rs2204008 0.652 rs11520002 chr12:38022179 G/T cg13010199 chr12:38710504 ALG10B 0.49 5.75 0.3 1.99e-8 Bladder cancer; LIHC cis rs7546668 1.000 rs7515244 chr1:15873386 A/G cg11706911 chr1:15910989 AGMAT 0.44 6.63 0.34 1.3100000000000001e-10 Glomerular filtration rate (creatinine); LIHC trans rs1973993 0.669 rs510552 chr1:96891671 A/G cg10631902 chr5:14652156 NA 0.37 9.92 0.47 1.53e-20 Weight; LIHC cis rs748404 0.723 rs565658 chr15:43556307 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.28 0.41 2.8e-15 Lung cancer; LIHC cis rs8062405 0.690 rs7187604 chr16:28565953 A/G cg00204512 chr16:28754710 NA 0.42 7.37 0.37 1.3e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9649213 0.593 rs6970801 chr7:97925240 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.82e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs7223966 1.000 rs12325866 chr17:61755974 G/A cg05941027 chr17:61774174 LIMD2 0.33 6.71 0.34 8.24e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2070433 0.752 rs11701058 chr21:47776382 T/C cg12379764 chr21:47803548 PCNT 0.75 10.44 0.49 2.53e-22 Lymphocyte counts; LIHC trans rs7677751 0.806 rs7678144 chr4:55102425 T/C cg17183009 chr3:120277827 NA 0.52 6.06 0.31 3.65e-9 Corneal astigmatism; LIHC cis rs12220238 0.841 rs10824161 chr10:76133762 C/G cg19889307 chr10:75911429 ADK;AP3M1 -0.63 -6.41 -0.33 4.8e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs765787 0.530 rs4775819 chr15:45525966 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.05e-13 Uric acid levels; LIHC cis rs4901869 0.966 rs9972206 chr14:59336095 A/G cg02291164 chr14:59296302 NA 0.48 6.06 0.31 3.64e-9 Panic disorder; LIHC cis rs765787 0.530 rs4775844 chr15:45542048 T/C cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC cis rs597539 0.652 rs478647 chr11:68700424 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.73 10.11 0.48 3.28e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs8177253 0.530 rs8177177 chr3:133463195 A/G cg24879335 chr3:133465180 TF 0.31 7.02 0.35 1.19e-11 Iron status biomarkers; LIHC cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg21724239 chr8:58056113 NA 0.47 6.24 0.32 1.32e-9 Developmental language disorder (linguistic errors); LIHC cis rs933688 1.000 rs12654787 chr5:90713259 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.37 0.66 6.68e-45 Smoking behavior; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.17 -0.32 1.91e-9 Total body bone mineral density; LIHC cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg12463550 chr7:65579703 CRCP 0.69 7.33 0.37 1.68e-12 Diabetic kidney disease; LIHC cis rs742115 0.510 rs9468839 chr6:11308035 A/T cg25250968 chr6:11318770 NEDD9 0.38 6.03 0.31 4.2e-9 Coronary artery disease; LIHC trans rs2727020 0.595 rs11040328 chr11:49339055 T/C cg03929089 chr4:120376271 NA -0.47 -7.22 -0.36 3.45e-12 Coronary artery disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00006032 chr14:66974439 GPHN 0.49 7.72 0.39 1.3e-13 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08247611 chr16:71928811 KIAA0174 0.42 6.04 0.31 4.09e-9 Pancreatic cancer; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.87 0.78 6.99e-71 Height; LIHC cis rs17776563 0.959 rs1348002 chr15:89113138 C/G cg05013243 chr15:89149849 MIR1179 0.38 6.57 0.33 1.85e-10 Thyroid hormone levels; LIHC cis rs7208859 0.673 rs12949860 chr17:29223032 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.55 0.33 2.18e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs877282 0.891 rs12357999 chr10:796468 A/C cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs7208859 0.623 rs8067338 chr17:29102345 T/C cg14067834 chr17:29058358 SUZ12P 0.72 7.12 0.36 6.39e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17125944 0.686 rs6572869 chr14:53353454 C/T cg00686598 chr14:53173677 PSMC6 0.78 8.7 0.43 1.43e-16 Alzheimer's disease (late onset); LIHC trans rs6489882 0.703 rs6489865 chr12:113360302 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg24642844 chr7:1081250 C7orf50 -0.92 -8.96 -0.44 2.13e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg00750074 chr16:89608354 SPG7 -0.37 -5.72 -0.3 2.28e-8 Multiple myeloma (IgH translocation); LIHC cis rs17784882 0.521 rs11713693 chr3:47074906 T/C cg16586182 chr3:47516702 SCAP 0.47 8.3 0.41 2.39e-15 QT interval; LIHC cis rs7945718 0.967 rs1440286 chr11:12809152 G/A cg25843174 chr11:12811716 TEAD1 0.37 8.47 0.42 7.26e-16 Educational attainment (years of education); LIHC cis rs4665809 1.000 rs3910272 chr2:26287842 T/A cg27170947 chr2:26402098 FAM59B -0.68 -8.34 -0.41 1.88e-15 Gut microbiome composition (summer); LIHC cis rs11673344 0.670 rs568654 chr19:37431187 G/A cg27390819 chr19:37464633 NA -0.5 -6.01 -0.31 4.88e-9 Obesity-related traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01623343 chr16:354374 AXIN1 -0.39 -6.2 -0.32 1.64e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3784262 0.512 rs4646572 chr15:58343021 T/C cg12031962 chr15:58353849 ALDH1A2 -0.31 -6.29 -0.32 9.95e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs8010715 1.000 rs3742500 chr14:24611978 G/T cg23112188 chr14:24563095 PCK2 -0.29 -5.9 -0.3 8.87e-9 IgG glycosylation; LIHC cis rs2439831 0.867 rs2927072 chr15:43922398 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.28 0.45 2.02e-18 Lung cancer in ever smokers; LIHC cis rs920590 0.921 rs4922099 chr8:19648486 T/C cg03894339 chr8:19674705 INTS10 0.44 6.63 0.34 1.28e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs2933343 0.700 rs1683787 chr3:128627021 C/T cg24203234 chr3:128598194 ACAD9 -0.43 -6.1 -0.31 2.85e-9 IgG glycosylation; LIHC trans rs116095464 0.681 rs10060016 chr5:241100 T/C cg00938859 chr5:1591904 SDHAP3 0.58 7.11 0.36 7.03e-12 Breast cancer; LIHC cis rs4742903 0.935 rs12351370 chr9:106928940 G/A cg14250997 chr9:106856677 SMC2 0.36 6.02 0.31 4.43e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs801193 1.000 rs1553609 chr7:66197139 T/C cg18876405 chr7:65276391 NA 0.43 7.48 0.37 6.44e-13 Aortic root size; LIHC cis rs6594499 0.872 rs7732974 chr5:110455381 T/C cg04022379 chr5:110408740 TSLP 0.49 8.28 0.41 2.79e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2797685 1.000 rs2859390 chr1:7847529 A/G cg04725166 chr1:7887271 PER3 -0.41 -7.35 -0.37 1.46e-12 Crohn's disease; LIHC cis rs13631 0.965 rs9411307 chr9:139994947 C/T cg14289826 chr9:140003911 NA 0.51 9.16 0.44 4.83e-18 Cerebrospinal fluid biomarker levels; LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg04013166 chr16:89971882 TCF25 0.63 8.52 0.42 5.31e-16 Skin colour saturation; LIHC cis rs9911578 1.000 rs391370 chr17:56675050 A/C cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs2932538 0.583 rs2279500 chr1:113244433 T/C cg22162597 chr1:113214053 CAPZA1 -0.68 -8.06 -0.4 1.25e-14 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs2073300 1.000 rs6137966 chr20:23444359 A/T cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7945718 0.934 rs11022478 chr11:12741104 T/C cg25843174 chr11:12811716 TEAD1 0.29 6.68 0.34 9.78e-11 Educational attainment (years of education); LIHC cis rs362296 0.698 rs3135168 chr4:3262699 T/C cg06533319 chr4:3265114 C4orf44 0.34 6.51 0.33 2.63e-10 Parental longevity (mother's age at death); LIHC cis rs9640161 0.702 rs3735175 chr7:150020457 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.37 -0.41 1.52e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs4819052 0.851 rs1999335 chr21:46670613 A/G cg22633049 chr21:46681294 NA -0.36 -6.11 -0.31 2.64e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg12923728 chr3:195709715 SDHAP1 -0.55 -6.24 -0.32 1.3e-9 Lung disease severity in cystic fibrosis; LIHC cis rs10916814 0.655 rs4291476 chr1:20897019 A/G cg24502330 chr1:20914028 CDA -0.31 -6.82 -0.35 4.1e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs6058796 0.792 rs35938376 chr20:31270536 G/A cg02600331 chr11:130417168 NA 0.36 7.59 0.38 2.98e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC trans rs2749592 0.531 rs1208559 chr10:38221370 T/C cg23533926 chr12:111358616 MYL2 0.34 6.83 0.35 3.88e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs796364 0.951 rs281776 chr2:200834282 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.28 0.45 1.99e-18 Schizophrenia; LIHC trans rs13098911 0.540 rs35477280 chr3:45974092 G/A cg21656520 chr2:210867290 RPE 0.86 6.09 0.31 3.09e-9 Celiac disease; LIHC cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg02503808 chr4:7069936 GRPEL1 0.79 11.81 0.54 3.14e-27 Monocyte percentage of white cells; LIHC cis rs10857712 0.754 rs7921041 chr10:135229239 G/C cg01444801 chr10:135216882 MTG1 -0.64 -9.68 -0.46 9.5e-20 Systemic lupus erythematosus; LIHC cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg06481639 chr22:41940642 POLR3H 0.6 5.8 0.3 1.55e-8 Vitiligo; LIHC cis rs950169 0.887 rs220333 chr15:85091133 C/T cg03959625 chr15:84868606 LOC388152 0.48 6.74 0.34 6.86e-11 Schizophrenia; LIHC cis rs867186 0.614 rs74358111 chr20:33399077 C/A cg08999081 chr20:33150536 PIGU 0.61 5.98 0.31 5.59e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs6586163 0.509 rs2031610 chr10:90754487 T/C cg03111039 chr10:90751583 FAS;ACTA2 0.79 12.62 0.56 3.16e-30 Chronic lymphocytic leukemia; LIHC cis rs7193541 0.684 rs9929496 chr16:74668473 G/A cg01733217 chr16:74700730 RFWD3 0.92 22.35 0.77 7.64e-69 Multiple myeloma; LIHC cis rs67478160 0.619 rs8018062 chr14:104281954 C/T cg08213375 chr14:104286397 PPP1R13B 0.65 12.56 0.56 4.96e-30 Schizophrenia; LIHC cis rs61612642 0.537 rs6915565 chr6:42192582 G/A cg01092361 chr6:42185687 MRPS10 0.9 8.91 0.43 2.99e-17 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs11696739 1.000 rs11696739 chr20:1600925 A/G cg15722679 chr20:1638393 SIRPG -0.34 -6.55 -0.33 2.07e-10 Mean platelet volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23800573 chr21:45114399 RRP1B 0.43 6.48 0.33 3.17e-10 Pancreatic cancer; LIHC cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg04267008 chr7:1944627 MAD1L1 -0.59 -9.1 -0.44 7.62e-18 Bipolar disorder and schizophrenia; LIHC cis rs752010 0.806 rs1109255 chr1:42091708 C/T cg06885757 chr1:42089581 HIVEP3 0.28 5.77 0.3 1.81e-8 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs864643 1.000 rs581691 chr3:39550735 T/C cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs1664789 0.904 rs1694058 chr5:53277415 G/A ch.5.1024479R chr5:53302184 ARL15 0.54 8.37 0.41 1.45e-15 Waist circumference adjusted for body mass index; LIHC cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg13393036 chr8:95962371 TP53INP1 -0.44 -10.28 -0.49 8.82e-22 Type 2 diabetes; LIHC cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg20607798 chr8:58055168 NA 0.49 6.2 0.32 1.6e-9 Developmental language disorder (linguistic errors); LIHC cis rs7739232 0.920 rs7748828 chr6:53517643 A/C cg15658676 chr6:53530538 KLHL31 -1.1 -7.88 -0.39 4.36e-14 Hip circumference adjusted for BMI; LIHC cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC cis rs748404 0.660 rs690512 chr15:43717678 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.15 0.36 5.42e-12 Lung cancer; LIHC trans rs2727020 0.595 rs11040416 chr11:49566429 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -22.17 -0.77 3.95e-68 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21813546 chr1:182808991 DHX9 0.44 6.73 0.34 7.04e-11 Pancreatic cancer; LIHC cis rs7523273 0.548 rs3109808 chr1:207948477 C/A cg22525895 chr1:207977042 MIR29B2 0.61 10.1 0.48 3.67e-21 Schizophrenia; LIHC cis rs4979906 1.000 rs4979910 chr10:79456561 T/C cg07817648 chr10:79422355 NA -0.33 -6.85 -0.35 3.4e-11 Mortality in heart failure; LIHC cis rs17401966 1.000 rs1339458 chr1:10328338 C/T cg15208524 chr1:10270712 KIF1B 0.45 6.53 0.33 2.4e-10 Hepatocellular carcinoma; LIHC cis rs5769765 0.773 rs9616378 chr22:50311973 A/G cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg12923728 chr3:195709715 SDHAP1 -0.57 -6.61 -0.34 1.52e-10 Lung disease severity in cystic fibrosis; LIHC cis rs3617 0.539 rs11130331 chr3:52956918 G/A cg11645453 chr3:52864694 ITIH4 -0.21 -5.74 -0.3 2.05e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9443189 0.570 rs6931578 chr6:76272310 C/T cg01950844 chr6:76311363 SENP6 0.89 11.17 0.52 6.49e-25 Prostate cancer; LIHC cis rs2074585 0.708 rs2589939 chr15:90930875 C/T cg22089800 chr15:90895588 ZNF774 0.6 8.41 0.41 1.13e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs1865760 0.929 rs9461224 chr6:25936402 G/T cg18357526 chr6:26021779 HIST1H4A 0.43 6.31 0.32 8.89e-10 Height; LIHC cis rs6815814 0.861 rs11936050 chr4:38789524 C/T cg06935464 chr4:38784597 TLR10 0.52 8.86 0.43 4.58e-17 Breast cancer; LIHC cis rs7552404 0.731 rs61770556 chr1:76421902 T/C cg03433033 chr1:76189801 ACADM 0.58 6.93 0.35 2.07e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6754311 0.731 rs892715 chr2:136576577 T/C cg07169764 chr2:136633963 MCM6 -0.67 -9.97 -0.47 9.98e-21 Mosquito bite size; LIHC cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg11645453 chr3:52864694 ITIH4 0.22 5.73 0.3 2.23e-8 Bipolar disorder; LIHC cis rs34779708 0.900 rs73262807 chr10:35496386 C/T cg03585969 chr10:35415529 CREM 0.85 12.81 0.57 6.11e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6089829 0.962 rs6089824 chr20:61659207 A/G cg03213289 chr20:61660250 NA 0.51 9.06 0.44 1.04e-17 Prostate cancer (SNP x SNP interaction); LIHC trans rs1005277 0.579 rs1780139 chr10:38503018 C/T cg17830980 chr10:43048298 ZNF37B -0.5 -9.6 -0.46 1.8e-19 Extrinsic epigenetic age acceleration; LIHC cis rs2463822 1.000 rs2513744 chr11:62077785 C/A cg06239285 chr11:62104954 ASRGL1 0.93 6.95 0.35 1.87e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC trans rs801193 1.000 rs2055682 chr7:66260289 A/G cg26939375 chr7:64535504 NA 0.39 6.19 0.32 1.69e-9 Aortic root size; LIHC cis rs7100689 0.754 rs1934695 chr10:82125230 T/C cg00277334 chr10:82204260 NA -0.54 -6.68 -0.34 9.51e-11 Post bronchodilator FEV1; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg25321988 chr19:49946433 NA -0.49 -6.18 -0.32 1.85e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg07092213 chr7:1199455 ZFAND2A -0.46 -7.11 -0.36 6.71e-12 Longevity;Endometriosis; LIHC cis rs4803468 1.000 rs3213861 chr19:41919944 A/C cg14132834 chr19:41945861 ATP5SL -0.43 -6.4 -0.33 5.17e-10 Height; LIHC cis rs875971 0.660 rs1860470 chr7:66103694 G/C cg11764359 chr7:65958608 NA -0.7 -10.36 -0.49 4.77e-22 Aortic root size; LIHC trans rs9929218 0.954 rs4552018 chr16:68822854 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.18 -0.4 5.53e-15 Colorectal cancer; LIHC cis rs7776786 0.870 rs12540224 chr7:18830489 C/T cg13420273 chr7:18810212 HDAC9 -0.26 -5.78 -0.3 1.67e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs1728785 1.000 rs1170426 chr16:68603798 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs7187994 0.848 rs8051512 chr16:84781101 C/G cg07647771 chr16:84786436 USP10 -0.33 -6.55 -0.33 2.1e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10220309 0.628 rs10138520 chr14:80572248 T/C cg08183125 chr14:80678293 DIO2 0.38 5.88 0.3 9.78e-9 Lung function (FEV1); LIHC cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg02503808 chr4:7069936 GRPEL1 -0.69 -10.11 -0.48 3.45e-21 Monocyte percentage of white cells; LIHC cis rs763121 0.853 rs6001173 chr22:39015302 A/G cg21395723 chr22:39101663 GTPBP1 0.4 6.67 0.34 1.06e-10 Menopause (age at onset); LIHC cis rs11971779 0.680 rs6954531 chr7:139054706 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs9457247 0.765 rs10946203 chr6:167446735 A/C cg07741184 chr6:167504864 NA 0.32 7.15 0.36 5.27e-12 Crohn's disease; LIHC cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.66 -0.38 1.93e-13 Electroencephalogram traits; LIHC cis rs74417235 0.517 rs13179034 chr5:154059487 C/A cg19735590 chr5:154026979 NA 0.47 5.82 0.3 1.39e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs4563143 0.704 rs16961809 chr19:29226299 C/T cg04546413 chr19:29218101 NA 0.39 7.51 0.38 5.1e-13 Methadone dose in opioid dependence; LIHC trans rs9747201 1.000 rs58119191 chr17:80155329 T/C cg07393940 chr7:158741817 NA 0.56 6.73 0.34 7.12e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6570726 0.935 rs416987 chr6:145847005 G/C cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs921968 0.541 rs588770 chr2:219494638 T/C cg02985541 chr2:219472218 PLCD4 0.43 7.15 0.36 5.37e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs1707322 0.896 rs809774 chr1:46560244 T/A cg03146154 chr1:46216737 IPP -0.47 -7.68 -0.38 1.69e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7818688 0.697 rs11787303 chr8:95972864 C/T cg16049864 chr8:95962084 TP53INP1 0.57 6.33 0.32 7.64e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6788895 1.000 rs73006998 chr3:150464271 G/A cg07663535 chr3:150480033 SIAH2 0.59 7.07 0.36 8.65e-12 Breast cancer; LIHC cis rs10193935 0.901 rs10196091 chr2:42541591 T/C cg27598129 chr2:42591480 NA -0.72 -10.87 -0.51 7.91e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs4561483 0.801 rs33619 chr16:12008941 T/G cg08843971 chr16:11963173 GSPT1 -0.42 -8.3 -0.41 2.43e-15 Testicular germ cell tumor; LIHC cis rs4561483 0.645 rs2192645 chr16:11928019 C/T cg08843971 chr16:11963173 GSPT1 -0.38 -7.4 -0.37 1.08e-12 Testicular germ cell tumor; LIHC cis rs875971 1.000 rs1540651 chr7:65650121 C/T cg11764359 chr7:65958608 NA -0.89 -15.52 -0.64 1.66e-41 Aortic root size; LIHC cis rs155076 0.711 rs4770131 chr13:21897468 A/G cg14456004 chr13:21872349 NA 1.19 13.34 0.58 5.74e-33 White matter hyperintensity burden; LIHC cis rs735396 1.000 rs1169311 chr12:121440731 C/T cg02403541 chr12:121454288 C12orf43 0.47 8.27 0.41 3.07e-15 N-glycan levels; LIHC cis rs6964587 0.869 rs2023784 chr7:91524677 A/G cg17063962 chr7:91808500 NA -0.98 -18.56 -0.71 1.1e-53 Breast cancer; LIHC cis rs3818285 0.556 rs941864 chr10:111656948 T/C cg00817464 chr10:111662876 XPNPEP1 -0.51 -8.19 -0.4 5.22e-15 Superior crus of antihelix expression; LIHC cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg16434002 chr17:42200994 HDAC5 -0.48 -7.17 -0.36 4.64e-12 Total body bone mineral density; LIHC cis rs3106136 0.843 rs1344612 chr4:95265228 G/A cg11021082 chr4:95130006 SMARCAD1 0.4 7.24 0.36 3.08e-12 Capecitabine sensitivity; LIHC cis rs2839186 0.500 rs13049893 chr21:47707054 C/T cg00612595 chr21:47717864 NA -0.4 -6.31 -0.32 8.87e-10 Testicular germ cell tumor; LIHC cis rs8044995 0.563 rs3785116 chr16:68372730 G/A cg09835421 chr16:68378352 PRMT7 -0.86 -9.83 -0.47 2.93e-20 Schizophrenia; LIHC trans rs7246657 0.943 rs7252346 chr19:37914682 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs1552244 0.882 rs3755783 chr3:10029289 A/G cg13047869 chr3:10149882 C3orf24 0.44 6.0 0.31 5.17e-9 Alzheimer's disease; LIHC cis rs1003719 0.788 rs4817849 chr21:38469796 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg12310025 chr6:25882481 NA -0.62 -8.78 -0.43 8.07e-17 Blood metabolite levels; LIHC trans rs35110281 0.748 rs1584918 chr21:45042419 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.21e-9 Mean corpuscular volume; LIHC cis rs7777484 0.534 rs2533890 chr7:2828743 C/T cg19717773 chr7:2847554 GNA12 -0.45 -8.74 -0.43 1.05e-16 Height; LIHC cis rs611744 0.624 rs2514844 chr8:109064809 A/G cg21045802 chr8:109455806 TTC35 0.43 7.22 0.36 3.39e-12 Dupuytren's disease; LIHC cis rs1941023 0.503 rs2233238 chr11:60145441 G/C cg08716584 chr11:60157161 MS4A7 -0.35 -8.08 -0.4 1.12e-14 Congenital heart disease (maternal effect); LIHC cis rs3809566 0.963 rs3809565 chr15:63333619 A/G cg12160578 chr15:63334699 TPM1 -0.62 -8.73 -0.43 1.18e-16 Platelet count; LIHC cis rs8180040 0.620 rs9875235 chr3:47083621 G/A cg27129171 chr3:47204927 SETD2 0.55 9.12 0.44 6.66e-18 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25777971 chr15:22945134 CYFIP1 0.42 6.34 0.32 7.47e-10 Pancreatic cancer; LIHC cis rs1348850 0.634 rs2293471 chr2:178487729 T/G cg27490568 chr2:178487706 NA 0.8 10.21 0.48 1.6e-21 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs875971 0.767 rs61348003 chr7:66005934 C/T cg11764359 chr7:65958608 NA 0.78 13.62 0.59 4.71e-34 Aortic root size; LIHC cis rs6424115 1.000 rs7515969 chr1:24158398 G/A cg10978503 chr1:24200527 CNR2 -0.38 -9.0 -0.44 1.64e-17 Immature fraction of reticulocytes; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01301323 chr12:77252588 CSRP2 0.44 6.71 0.34 7.87e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs17301259 0.729 rs2519923 chr7:88380200 G/A cg07470830 chr6:76000847 NA 0.36 6.05 0.31 3.75e-9 Heschl's gyrus morphology; LIHC cis rs240764 0.853 rs12206182 chr6:101033379 A/C cg09795085 chr6:101329169 ASCC3 -0.49 -6.67 -0.34 1.04e-10 Neuroticism; LIHC cis rs9948 0.786 rs62156230 chr2:97424915 A/G cg01990225 chr2:97406019 LMAN2L -0.7 -6.4 -0.33 5.17e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1008375 0.966 rs1476836 chr4:17585014 G/C cg02297831 chr4:17616191 MED28 0.48 7.24 0.36 2.99e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs801193 0.660 rs974239 chr7:66213491 G/A cg18252515 chr7:66147081 NA -0.44 -6.33 -0.32 7.5e-10 Aortic root size; LIHC cis rs1005277 0.579 rs1780138 chr10:38501654 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC trans rs208520 0.954 rs72884027 chr6:66995044 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.67 7.2 0.36 3.84e-12 Exhaled nitric oxide output; LIHC cis rs7582180 0.607 rs1530029 chr2:100968205 C/T cg14675211 chr2:100938903 LONRF2 0.53 8.35 0.41 1.68e-15 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.502 rs11514371 chr12:38306306 G/C cg26384229 chr12:38710491 ALG10B 0.6 8.19 0.4 5.23e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs12594515 0.967 rs11070466 chr15:45984955 C/T cg06207120 chr15:45996521 NA 0.33 6.44 0.33 4.12e-10 Waist circumference;Weight; LIHC cis rs6952808 0.929 rs1801368 chr7:1976457 C/T cg14004847 chr7:1930337 MAD1L1 -0.43 -6.21 -0.32 1.58e-9 Bipolar disorder and schizophrenia; LIHC cis rs12200782 0.530 rs9379892 chr6:26582414 G/A cg12826209 chr6:26865740 GUSBL1 0.52 6.45 0.33 3.77e-10 Small cell lung carcinoma; LIHC cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg08499158 chr17:42289980 UBTF -0.52 -8.46 -0.42 8.13e-16 Total body bone mineral density; LIHC cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg23978390 chr7:1156363 C7orf50 0.55 8.05 0.4 1.41e-14 Longevity;Endometriosis; LIHC cis rs7917772 0.582 rs7906115 chr10:104327164 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.17e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs72627123 0.867 rs73303113 chr14:74481068 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.43 0.45 6.42e-19 Morning vs. evening chronotype; LIHC cis rs7940866 0.845 rs10894294 chr11:130830748 G/T cg12179176 chr11:130786555 SNX19 0.51 7.55 0.38 3.9e-13 Schizophrenia; LIHC cis rs9918079 0.560 rs13147590 chr4:15621188 A/G cg04067612 chr4:15429572 C1QTNF7 0.28 5.88 0.3 1e-8 Obesity-related traits; LIHC cis rs4665809 1.000 rs750452 chr2:26324995 G/A cg04944784 chr2:26401820 FAM59B -0.65 -8.37 -0.41 1.53e-15 Gut microbiome composition (summer); LIHC cis rs11676348 0.846 rs11677534 chr2:219007060 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.06 -0.31 3.5e-9 Ulcerative colitis; LIHC cis rs77633900 0.614 rs280033 chr15:77023099 G/A cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg09222892 chr1:25734099 RHCE -0.46 -8.57 -0.42 3.54e-16 Erythrocyte sedimentation rate; LIHC cis rs1046896 0.552 rs12602280 chr17:80805421 G/C cg22027946 chr17:80790580 TBCD;ZNF750 0.52 7.53 0.38 4.63e-13 Glycated hemoglobin levels; LIHC cis rs79149102 0.579 rs7166105 chr15:75343942 A/G cg16226627 chr15:75307476 SCAMP5 -0.55 -9.69 -0.46 9.17e-20 Lung cancer; LIHC cis rs2120019 1.000 rs7173833 chr15:75369618 C/T cg09165964 chr15:75287851 SCAMP5 -0.55 -8.93 -0.43 2.64e-17 Blood trace element (Zn levels); LIHC cis rs1577917 0.883 rs2782263 chr6:86791307 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.34 -5.87 -0.3 1.02e-8 Response to antipsychotic treatment; LIHC cis rs7572733 0.515 rs35730302 chr2:198818626 A/T cg03934865 chr2:198174659 NA -0.48 -6.89 -0.35 2.76e-11 Dermatomyositis; LIHC cis rs7116495 0.609 rs7115513 chr11:71664495 T/A cg10381502 chr11:71823885 C11orf51 -1.0 -8.24 -0.41 3.84e-15 Severe influenza A (H1N1) infection; LIHC cis rs748404 0.660 rs690367 chr15:43748304 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.45 -7.03 -0.36 1.12e-11 Lung cancer; LIHC cis rs9399137 0.507 rs4580893 chr6:135297662 G/A cg24558204 chr6:135376177 HBS1L 0.6 10.38 0.49 4.14e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs3096299 0.679 rs3096322 chr16:89441123 A/G cg01788221 chr16:89496183 ANKRD11 0.41 6.33 0.32 7.83e-10 Multiple myeloma (IgH translocation); LIHC cis rs34172651 0.687 rs8044992 chr16:24811207 T/C cg00339695 chr16:24857497 SLC5A11 0.51 7.78 0.39 8.58e-14 Intelligence (multi-trait analysis); LIHC cis rs4660306 0.961 rs7539253 chr1:45947420 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC -0.65 -7.77 -0.39 9.35e-14 Homocysteine levels; LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg15463628 chr8:11872659 NA -0.48 -6.51 -0.33 2.63e-10 Monocyte count; LIHC cis rs6967414 0.786 rs7782227 chr7:6748594 T/C cg00387323 chr7:6746715 ZNF12 0.64 7.04 0.36 1.07e-11 Hematocrit;Hemoglobin concentration; LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg22528358 chr1:107598549 PRMT6 -0.69 -11.36 -0.52 1.32e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.862 rs801209 chr7:66019390 G/T cg18252515 chr7:66147081 NA 0.46 6.8 0.35 4.67e-11 Aortic root size; LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg00612595 chr21:47717864 NA -0.36 -5.85 -0.3 1.12e-8 Testicular germ cell tumor; LIHC cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg10560079 chr2:191398806 TMEM194B -0.49 -7.53 -0.38 4.65e-13 Pulse pressure; LIHC trans rs75804782 0.641 rs56134361 chr2:239318905 A/G cg01134436 chr17:81009848 B3GNTL1 0.81 6.6 0.34 1.61e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs6138458 1.000 rs6114984 chr20:24976610 A/G cg26195577 chr20:24973756 C20orf3 1.2 16.23 0.66 2.61e-44 Blood protein levels; LIHC cis rs8067354 0.872 rs2645466 chr17:57853214 A/C cg13753209 chr17:57696993 CLTC 0.56 8.63 0.42 2.34e-16 Hemoglobin concentration; LIHC cis rs921968 0.643 rs524902 chr2:219433357 A/C cg17980119 chr2:219472607 PLCD4 0.34 5.79 0.3 1.62e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs1577917 0.560 rs9450288 chr6:86221586 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.39 6.98 0.35 1.58e-11 Response to antipsychotic treatment; LIHC trans rs62458065 0.513 rs787220 chr7:32581139 C/G cg00845942 chr12:64062724 DPY19L2 -0.56 -6.03 -0.31 4.17e-9 Metabolite levels (HVA/MHPG ratio); LIHC trans rs3780486 0.505 rs10813958 chr9:33165985 A/G cg20290983 chr6:43655470 MRPS18A 0.84 15.1 0.63 8.03e-40 IgG glycosylation; LIHC cis rs2075371 0.933 rs1421480 chr7:133958114 A/C cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.68e-14 Mean platelet volume; LIHC cis rs12908161 1.000 rs60957376 chr15:85280792 T/G cg12863693 chr15:85201151 NMB 0.47 6.84 0.35 3.59e-11 Schizophrenia; LIHC cis rs7520050 0.966 rs1707335 chr1:46571921 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.58e-9 Red blood cell count;Reticulocyte count; LIHC cis rs477692 0.663 rs491929 chr10:131368111 G/A cg05714579 chr10:131428358 MGMT 0.44 7.17 0.36 4.53e-12 Response to temozolomide; LIHC cis rs7520050 0.966 rs10789487 chr1:46420221 G/A cg03146154 chr1:46216737 IPP -0.38 -6.29 -0.32 9.84e-10 Red blood cell count;Reticulocyte count; LIHC cis rs6430585 0.583 rs3769008 chr2:136586183 C/T cg15123519 chr2:136567270 LCT -0.38 -5.82 -0.3 1.38e-8 Corneal structure; LIHC cis rs6062302 0.522 rs4809312 chr20:62234240 C/T cg09650180 chr20:62225654 GMEB2 -0.39 -6.03 -0.31 4.23e-9 Glioblastoma; LIHC cis rs7659604 0.676 rs4077102 chr4:122699830 A/G cg19748678 chr4:122722346 EXOSC9 0.65 10.52 0.49 1.36e-22 Type 2 diabetes; LIHC cis rs5769707 0.681 rs916360 chr22:50041972 T/C cg07959070 chr22:50026188 C22orf34 -0.34 -8.34 -0.41 1.8e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.17 0.32 1.89e-9 Menopause (age at onset); LIHC cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg02359409 chr6:42947317 PEX6 0.39 5.8 0.3 1.52e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg18306943 chr3:40428807 ENTPD3 -0.42 -7.46 -0.37 7.36e-13 Renal cell carcinoma; LIHC cis rs12364620 1 rs12364620 chr11:68252123 T/G cg16797656 chr11:68205561 LRP5 0.53 8.46 0.42 7.99e-16 Total body bone mineral density (age 0-15); LIHC cis rs9916302 0.904 rs4795356 chr17:37535631 C/T cg07936489 chr17:37558343 FBXL20 0.85 13.68 0.59 2.7200000000000002e-34 Glomerular filtration rate (creatinine); LIHC cis rs3749237 0.595 rs6797765 chr3:49423976 A/G cg03060546 chr3:49711283 APEH 0.58 9.48 0.46 4.31e-19 Resting heart rate; LIHC trans rs1814175 0.817 rs1319547 chr11:49916705 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs832187 0.640 rs56293138 chr3:63888935 G/C cg16258503 chr3:63850278 ATXN7;THOC7 -0.48 -6.83 -0.35 3.85e-11 Schizophrenia; LIHC cis rs9470366 0.509 rs4713996 chr6:36629714 C/T cg00935119 chr6:36647544 CDKN1A 0.46 6.63 0.34 1.34e-10 QRS duration; LIHC cis rs8177179 0.967 rs9869311 chr3:133451613 C/T cg16262614 chr3:133464971 TF 0.46 10.36 0.49 4.53e-22 Iron status biomarkers (transferrin levels); LIHC cis rs17666538 0.710 rs7834337 chr8:655828 A/G cg02524346 chr8:600233 NA 0.73 6.42 0.33 4.6e-10 IgG glycosylation; LIHC cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs208520 0.690 rs12204512 chr6:66710486 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.74 8.64 0.42 2.15e-16 Exhaled nitric oxide output; LIHC cis rs3106136 0.678 rs11944941 chr4:95298169 C/T cg11021082 chr4:95130006 SMARCAD1 0.36 6.13 0.31 2.4e-9 Capecitabine sensitivity; LIHC cis rs7666738 0.927 rs4699328 chr4:99055890 C/T cg05340658 chr4:99064831 C4orf37 0.68 12.07 0.55 3.36e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs4906332 0.782 rs7161305 chr14:104002234 G/A cg19000871 chr14:103996768 TRMT61A -0.54 -8.44 -0.42 8.89e-16 Coronary artery disease; LIHC cis rs3736485 0.934 rs8036609 chr15:51861426 C/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg12310025 chr6:25882481 NA -0.6 -7.39 -0.37 1.1e-12 Intelligence (multi-trait analysis); LIHC cis rs2439831 0.681 rs11858152 chr15:43634196 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.92 17.45 0.69 3.33e-49 Lung cancer in ever smokers; LIHC cis rs644799 0.965 rs2508713 chr11:95547927 T/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg00280220 chr17:61926910 NA 0.44 7.15 0.36 5.34e-12 Prudent dietary pattern; LIHC cis rs473651 0.904 rs10929275 chr2:239323169 A/G cg18131467 chr2:239335373 ASB1 1.05 19.42 0.72 3.87e-57 Multiple system atrophy; LIHC cis rs10174077 0.874 rs6750342 chr2:152485754 A/G cg06191203 chr2:152266755 RIF1 -0.43 -7.25 -0.36 2.81e-12 Squamous cell lung carcinoma; LIHC cis rs9368481 0.524 rs12530345 chr6:26884243 T/C cg18867708 chr6:26865862 GUSBL1 0.55 8.29 0.41 2.54e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg14983838 chr19:29218262 NA 0.48 7.85 0.39 5.23e-14 Methadone dose in opioid dependence; LIHC cis rs4919087 0.748 rs701813 chr10:98975632 C/T cg25902810 chr10:99078978 FRAT1 -0.54 -6.25 -0.32 1.22e-9 Monocyte count; LIHC cis rs10131894 0.611 rs174995 chr14:75434183 T/C cg11812906 chr14:75593930 NEK9 -0.67 -11.67 -0.53 1.05e-26 Coronary artery disease; LIHC cis rs922107 0.713 rs6702712 chr1:89947493 T/C cg15422784 chr1:90023713 LRRC8B 0.46 7.26 0.37 2.62e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs11031096 0.505 rs10835743 chr11:4226692 C/T cg18678763 chr11:4115507 RRM1 -0.45 -6.5 -0.33 2.91e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs6073597 1.000 rs6031980 chr20:43714384 C/T cg08997518 chr6:116601248 DSE;TSPYL1 0.44 6.32 0.32 7.99e-10 Positive affect; LIHC cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg08219700 chr8:58056026 NA 0.56 8.97 0.44 2.04e-17 Developmental language disorder (linguistic errors); LIHC trans rs9929218 0.911 rs4783686 chr16:68834156 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -8.13 -0.4 8.12e-15 Colorectal cancer; LIHC cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg08048268 chr3:133502702 NA -0.42 -6.25 -0.32 1.24e-9 Iron status biomarkers; LIHC cis rs727505 1.000 rs6943653 chr7:124512249 G/A cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.1e-9 Lewy body disease; LIHC cis rs3820500 0.543 rs2622362 chr1:118089166 T/G cg20383390 chr1:117909022 MAN1A2 -0.46 -5.84 -0.3 1.2e-8 Pneumonia; LIHC cis rs644799 1.000 rs1784135 chr11:95531748 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9486719 1.000 rs12214469 chr6:97019471 G/T cg06623918 chr6:96969491 KIAA0776 -0.7 -7.21 -0.36 3.53e-12 Migraine;Coronary artery disease; LIHC cis rs8017423 0.740 rs8003095 chr14:90680643 A/T cg14092571 chr14:90743983 NA -0.36 -5.76 -0.3 1.85e-8 Mortality in heart failure; LIHC cis rs868943 0.582 rs34001069 chr6:116483014 T/C cg08036074 chr6:116424633 NT5DC1 -0.62 -6.91 -0.35 2.32e-11 Total cholesterol levels; LIHC cis rs9916302 0.904 rs7503705 chr17:37669704 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC cis rs3768617 0.510 rs10752899 chr1:183081241 T/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.66 0.5 4.09e-23 Fuchs's corneal dystrophy; LIHC cis rs8060686 0.545 rs7199878 chr16:68186301 A/G cg05110241 chr16:68378359 PRMT7 -0.6 -6.58 -0.34 1.8e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs8062405 1.000 rs4788101 chr16:28867804 C/T cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7903847 0.642 rs11189182 chr10:99144186 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs965469 0.779 rs6037581 chr20:3351595 C/T cg25506879 chr20:3388711 C20orf194 -0.51 -6.27 -0.32 1.06e-9 IFN-related cytopenia; LIHC cis rs4319547 0.737 rs10846921 chr12:122943376 G/T cg23029597 chr12:123009494 RSRC2 0.47 6.83 0.35 3.78e-11 Body mass index; LIHC cis rs6835098 1.000 rs6835098 chr4:174089238 T/C cg27433088 chr4:174089019 GALNT7 0.4 7.31 0.37 1.87e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg14671364 chr1:107599128 PRMT6 0.48 6.99 0.35 1.45e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs477895 0.838 rs12794145 chr11:64006484 C/T cg05555928 chr11:63887634 MACROD1 0.47 6.13 0.31 2.41e-9 Mean platelet volume; LIHC cis rs8180040 0.726 rs2061197 chr3:47001350 C/T cg02527881 chr3:46936655 PTH1R 0.33 6.43 0.33 4.2e-10 Colorectal cancer; LIHC cis rs11864453 0.614 rs12445586 chr16:72126276 C/T cg16558253 chr16:72132732 DHX38 -0.51 -8.1 -0.4 9.86e-15 Fibrinogen levels; LIHC cis rs3823572 0.526 rs2971967 chr7:133642595 A/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.81 -0.3 1.4e-8 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.708 rs959558 chr9:123368911 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 7.86 0.39 5.18e-14 Hip circumference adjusted for BMI; LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg14393609 chr7:65229607 NA 0.41 6.87 0.35 3.13e-11 Calcium levels; LIHC cis rs6570726 0.967 rs439017 chr6:145806123 T/C cg23711669 chr6:146136114 FBXO30 0.51 9.28 0.45 1.98e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs3793683 0.858 rs1571145 chr10:134583672 C/G cg18305652 chr10:134549665 INPP5A -0.39 -6.3 -0.32 9.2e-10 Migraine; LIHC cis rs7432375 0.901 rs900818 chr3:136471815 C/T cg21827317 chr3:136751795 NA -0.44 -5.75 -0.3 2.01e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC trans rs7246657 0.943 rs2081096 chr19:37964700 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs1023500 1.000 rs1023498 chr22:42340569 C/T cg04733989 chr22:42467013 NAGA -0.5 -5.85 -0.3 1.17e-8 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18541421 chr13:111768813 ARHGEF7 0.5 6.95 0.35 1.88e-11 Lung function (FEV1/FVC); LIHC cis rs6461049 0.765 rs1476887 chr7:2151633 T/C cg02951883 chr7:2050386 MAD1L1 -0.63 -10.24 -0.48 1.25e-21 Schizophrenia; LIHC trans rs801193 1.000 rs7788576 chr7:66148302 G/A cg26939375 chr7:64535504 NA -0.43 -6.84 -0.35 3.64e-11 Aortic root size; LIHC trans rs11098499 0.739 rs951570 chr4:120150467 T/C cg25214090 chr10:38739885 LOC399744 -0.38 -6.25 -0.32 1.22e-9 Corneal astigmatism; LIHC cis rs8072100 0.935 rs4793978 chr17:45698175 G/A cg08085267 chr17:45401833 C17orf57 0.39 5.93 0.31 7.3e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs870825 0.860 rs60022249 chr4:185600772 T/C cg04058563 chr4:185651563 MLF1IP 0.75 6.44 0.33 4.08e-10 Blood protein levels; LIHC cis rs311392 0.902 rs411839 chr8:55092189 T/C cg20636351 chr8:55087400 NA -0.37 -7.65 -0.38 2.13e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs1538970 0.924 rs6657284 chr1:45879088 T/C cg24296786 chr1:45957014 TESK2 -0.5 -7.22 -0.36 3.42e-12 Platelet count; LIHC cis rs7568498 0.564 rs10490563 chr2:161914168 G/A cg16506815 chr2:162101123 NA -0.41 -6.25 -0.32 1.21e-9 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC cis rs67311347 1.000 rs2168111 chr3:40395325 T/G cg00656387 chr3:40428638 ENTPD3 0.41 6.87 0.35 2.97e-11 Renal cell carcinoma; LIHC cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg02951883 chr7:2050386 MAD1L1 -0.47 -7.07 -0.36 8.88e-12 Bipolar disorder and schizophrenia; LIHC cis rs2075371 0.796 rs35440439 chr7:134006094 C/T cg11752832 chr7:134001865 SLC35B4 0.45 5.74 0.3 2.1e-8 Mean platelet volume; LIHC cis rs2439831 0.850 rs3736180 chr15:44106624 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.42 0.33 4.42e-10 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11353984 chr5:65439984 SFRS12 -0.41 -6.08 -0.31 3.23e-9 Pancreatic cancer; LIHC cis rs9790314 0.543 rs1349352 chr3:161118486 C/T cg17135325 chr3:160939158 NMD3 0.47 7.11 0.36 6.79e-12 Morning vs. evening chronotype; LIHC cis rs6964587 1.000 rs6969536 chr7:91689351 C/G cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs4474465 0.688 rs10793336 chr11:78281867 A/G cg27205649 chr11:78285834 NARS2 0.5 7.6 0.38 2.89e-13 Alzheimer's disease (survival time); LIHC cis rs2455799 0.573 rs2455833 chr3:15752830 T/C cg12698662 chr3:15914712 MIR563 -0.38 -7.01 -0.35 1.32e-11 Mean platelet volume; LIHC cis rs10464366 0.544 rs12668821 chr7:39167846 T/A cg20302533 chr7:39170763 POU6F2 0.38 6.95 0.35 1.8e-11 IgG glycosylation; LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg05484376 chr2:27715224 FNDC4 0.38 6.51 0.33 2.74e-10 Total body bone mineral density; LIHC cis rs13217239 0.597 rs9467978 chr6:27024558 A/G cg18867708 chr6:26865862 GUSBL1 -0.52 -7.79 -0.39 7.87e-14 Schizophrenia; LIHC cis rs9942416 0.660 rs66493518 chr5:74990125 G/C cg19683494 chr5:74908142 NA 0.57 7.53 0.38 4.58e-13 Age-related disease endophenotypes; LIHC cis rs734999 0.588 rs4648652 chr1:2535758 A/G cg18854424 chr1:2615690 NA 0.33 7.36 0.37 1.42e-12 Ulcerative colitis; LIHC trans rs6934970 0.932 rs10456881 chr6:113052347 G/A cg09308777 chr6:169852575 NA 0.58 6.06 0.31 3.67e-9 Bipolar disorder (body mass index interaction); LIHC cis rs9309473 0.607 rs6740173 chr2:73602266 C/G cg20560298 chr2:73613845 ALMS1 -0.47 -7.42 -0.37 9.12e-13 Metabolite levels; LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg13395646 chr4:1353034 KIAA1530 -0.41 -6.01 -0.31 4.63e-9 Longevity; LIHC cis rs1568889 1.000 rs78140392 chr11:28203231 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.02 0.35 1.22e-11 Bipolar disorder; LIHC cis rs4453791 1.000 rs13094414 chr3:38930568 A/G cg02254461 chr3:39195904 CSRNP1 0.67 6.01 0.31 4.89e-9 Social communication problems; LIHC cis rs644799 1.000 rs516551 chr11:95588626 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.98 0.47 9.61e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1707322 0.682 rs12037459 chr1:46094959 T/G cg03146154 chr1:46216737 IPP 0.55 9.08 0.44 8.95e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9814567 1.000 rs7371896 chr3:134249769 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4908768 0.871 rs4908508 chr1:8800780 T/C cg20416874 chr1:8611966 RERE 0.48 6.63 0.34 1.3100000000000001e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7312933 0.501 rs3810793 chr12:42729407 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.75 0.39 1.05e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg05527609 chr1:210001259 C1orf107 0.42 6.31 0.32 8.56e-10 Cleft lip with or without cleft palate; LIHC cis rs7568458 0.709 rs762684 chr2:85782023 G/A cg02493740 chr2:85810744 VAMP5 -0.48 -7.97 -0.4 2.43e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs796364 1.000 rs10178177 chr2:200829993 G/A cg23649088 chr2:200775458 C2orf69 0.49 5.97 0.31 6.04e-9 Schizophrenia; LIHC cis rs208520 0.837 rs208471 chr6:66916749 A/C cg07460842 chr6:66804631 NA -0.7 -7.81 -0.39 7.21e-14 Exhaled nitric oxide output; LIHC cis rs2730245 0.851 rs2657333 chr7:158728743 G/A cg24397884 chr7:158709396 WDR60 -0.42 -6.54 -0.33 2.29e-10 Height; LIHC cis rs903552 1.000 rs4965386 chr15:102003207 G/A cg19295451 chr15:102010161 PCSK6 -0.45 -6.36 -0.32 6.65e-10 Diabetic kidney disease; LIHC cis rs3806843 0.735 rs6849 chr5:140086191 G/T cg16577123 chr5:140027231 NDUFA2;IK -0.4 -5.72 -0.3 2.32e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs10503871 1.000 rs10503871 chr8:30436852 A/G cg26383811 chr8:30366931 RBPMS -0.43 -7.53 -0.38 4.58e-13 Metabolite levels (X-11787); LIHC cis rs8141529 0.732 rs6005881 chr22:29183133 A/G cg02153584 chr22:29168773 CCDC117 0.56 9.14 0.44 5.52e-18 Lymphocyte counts; LIHC cis rs9303401 0.659 rs7223708 chr17:56896398 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.32 0.58 6.47e-33 Cognitive test performance; LIHC cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg03517284 chr6:25882590 NA -0.6 -8.57 -0.42 3.56e-16 Blood metabolite levels; LIHC cis rs6597981 0.675 rs4963120 chr11:825777 A/G cg01741372 chr11:783889 NA -0.6 -9.43 -0.45 6.39e-19 Breast cancer; LIHC cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg27286337 chr10:134555280 INPP5A 0.89 13.24 0.58 1.41e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg15691649 chr6:25882328 NA 0.78 11.18 0.52 6.31e-25 Blood metabolite levels; LIHC cis rs9916302 0.808 rs12947281 chr17:37652210 G/T cg03013999 chr17:37608204 MED1 0.35 5.89 0.3 9.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs17376456 0.825 rs10051878 chr5:93064164 T/G cg25358565 chr5:93447407 FAM172A 1.05 9.49 0.46 4.21e-19 Diabetic retinopathy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12492359 chr2:203242268 BMPR2 0.51 6.89 0.35 2.64e-11 Lung function (FEV1/FVC); LIHC cis rs2769264 0.546 rs12071705 chr1:151430504 G/C cg18801370 chr1:151430492 POGZ 0.87 15.3 0.64 1.28e-40 Blood trace element (Cu levels); LIHC cis rs7927771 0.832 rs4992357 chr11:47393638 C/T cg20307385 chr11:47447363 PSMC3 -0.45 -5.91 -0.3 8.35e-9 Subjective well-being; LIHC trans rs61931739 0.500 rs35391785 chr12:34444478 C/T cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs782590 0.902 rs2586947 chr2:55854009 C/G cg03859395 chr2:55845619 SMEK2 0.87 15.3 0.64 1.26e-40 Metabolic syndrome; LIHC cis rs7296418 0.663 rs11057284 chr12:123830692 G/C cg00376283 chr12:123451042 ABCB9 0.62 10.35 0.49 5.15e-22 Platelet count; LIHC cis rs2845885 1.000 rs11231698 chr11:63877163 C/T cg05555928 chr11:63887634 MACROD1 -0.52 -6.43 -0.33 4.25e-10 Body mass index; LIHC trans rs7504990 0.754 rs1030594 chr18:50374030 T/C cg08535148 chr4:26321143 RBPJ 0.57 7.12 0.36 6.5e-12 Gallbladder cancer; LIHC cis rs4808199 1.000 rs17288409 chr19:19504167 T/C cg03709012 chr19:19516395 GATAD2A 1.08 19.25 0.72 1.76e-56 Nonalcoholic fatty liver disease; LIHC cis rs1580019 0.587 rs7806941 chr7:32553319 G/T cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.21 0.32 1.57e-9 Cognitive ability; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.23 -0.32 1.38e-9 Total body bone mineral density; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.19 -0.32 1.7e-9 Total body bone mineral density; LIHC cis rs9309473 0.607 rs7567343 chr2:73596605 C/A cg20560298 chr2:73613845 ALMS1 -0.45 -7.16 -0.36 5.13e-12 Metabolite levels; LIHC cis rs950169 0.541 rs10795 chr15:85177297 G/A cg12863693 chr15:85201151 NMB 0.48 6.87 0.35 3.13e-11 Schizophrenia; LIHC cis rs7903847 0.642 rs11817875 chr10:99158414 G/A cg08345082 chr10:99160200 RRP12 -0.4 -6.6 -0.34 1.6e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg08888203 chr3:10149979 C3orf24 0.56 6.39 0.33 5.49e-10 Alzheimer's disease; LIHC cis rs1538970 0.669 rs3219476 chr1:45802670 A/C cg24296786 chr1:45957014 TESK2 0.49 7.15 0.36 5.36e-12 Platelet count; LIHC trans rs12780046 0.656 rs5025590 chr10:100820860 C/T cg05980083 chr9:112191166 PTPN3 -0.49 -6.27 -0.32 1.11e-9 Non-glioblastoma glioma; LIHC cis rs11690935 0.921 rs908670 chr2:172690180 T/C cg13550731 chr2:172543902 DYNC1I2 -0.91 -16.96 -0.68 3.02e-47 Schizophrenia; LIHC cis rs5769765 0.773 rs9616383 chr22:50313014 T/C cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs8027181 1.000 rs8027181 chr15:73088869 A/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.5 7.81 0.39 7.29e-14 Triglyceride levels; LIHC cis rs72843506 0.586 rs113833946 chr17:19858906 T/C cg12065943 chr17:19881925 AKAP10 -0.4 -6.56 -0.33 2.02e-10 Schizophrenia; LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg05185784 chr16:90016020 DEF8 -0.46 -5.93 -0.31 7.39e-9 Skin colour saturation; LIHC cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs763014 0.966 rs35642938 chr16:642249 T/C cg07343612 chr16:622815 PIGQ -0.84 -15.12 -0.63 6.77e-40 Height; LIHC cis rs7312933 0.558 rs3747560 chr12:42719890 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.54 -8.0 -0.4 1.89e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1355223 1.000 rs11601923 chr11:34764354 C/G cg11058730 chr11:34937778 PDHX;APIP -0.48 -6.63 -0.34 1.32e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg06873352 chr17:61820015 STRADA 0.55 9.19 0.45 3.87e-18 Prudent dietary pattern; LIHC cis rs2072499 0.722 rs61462713 chr1:156161682 C/T cg25208724 chr1:156163844 SLC25A44 0.72 8.19 0.4 5.38e-15 Testicular germ cell tumor; LIHC cis rs2242116 0.592 rs2290545 chr3:46967040 C/T cg27129171 chr3:47204927 SETD2 0.44 6.49 0.33 3.01e-10 Birth weight; LIHC cis rs881375 0.678 rs2269060 chr9:123683569 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.41 6.08 0.31 3.3e-9 Rheumatoid arthritis; LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.88 0.3 9.7e-9 Tonsillectomy; LIHC cis rs7647973 1.000 rs11928090 chr3:49604904 G/A cg07636037 chr3:49044803 WDR6 0.51 6.46 0.33 3.68e-10 Menarche (age at onset); LIHC cis rs12079745 0.793 rs12063863 chr1:169269557 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -7.11 -0.36 6.7e-12 QT interval; LIHC cis rs9596863 1.000 rs9568940 chr13:54419251 C/A ch.13.53330881F chr13:54432880 NA 0.44 5.97 0.31 5.84e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs7412746 0.658 rs6657388 chr1:150748786 A/G cg18016565 chr1:150552671 MCL1 0.54 10.05 0.48 5.25e-21 Melanoma; LIHC trans rs1200821 0.535 rs1938417 chr10:37687520 A/C cg25427524 chr10:38739819 LOC399744 0.39 6.29 0.32 9.75e-10 Hemostatic factors and hematological phenotypes; LIHC cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg03517284 chr6:25882590 NA 0.61 8.78 0.43 8.07e-17 Blood metabolite levels; LIHC cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg18306943 chr3:40428807 ENTPD3 -0.34 -5.94 -0.31 7.1e-9 Renal cell carcinoma; LIHC cis rs9309473 0.861 rs6546857 chr2:73837955 A/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.48 -0.33 3.17e-10 Metabolite levels; LIHC cis rs765787 0.530 rs2899381 chr15:45529630 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.05e-13 Uric acid levels; LIHC cis rs7587476 0.601 rs6715570 chr2:215673440 T/C cg04004882 chr2:215674386 BARD1 -0.59 -8.49 -0.42 6.61e-16 Neuroblastoma; LIHC trans rs11157436 0.918 rs1983518 chr14:22617290 A/T cg13567813 chr19:50879636 NR1H2 0.43 6.31 0.32 8.75e-10 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs116095464 0.558 rs10055993 chr5:264296 A/C cg22857025 chr5:266934 NA -1.55 -16.34 -0.66 8.8e-45 Breast cancer; LIHC cis rs2795502 0.935 rs2744060 chr10:43262616 C/G cg20628663 chr10:43360327 NA -0.46 -6.84 -0.35 3.68e-11 Blood protein levels; LIHC cis rs4970988 0.556 rs6695123 chr1:150563483 T/C cg17724175 chr1:150552817 MCL1 -0.55 -11.0 -0.51 2.76e-24 Urate levels; LIHC trans rs4596713 0.507 rs10217120 chr9:71794919 A/G cg16512924 chr15:28394682 HERC2 0.38 6.17 0.32 1.92e-9 Headache; LIHC cis rs2204008 0.605 rs4608149 chr12:38132057 G/C cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs6951245 0.872 rs75280240 chr7:1058511 C/T cg08132940 chr7:1081526 C7orf50 -0.74 -6.33 -0.32 7.56e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1691799 0.899 rs1168357 chr12:66749879 T/C cg16791601 chr12:66731901 HELB -0.55 -13.52 -0.59 1.17e-33 White blood cell count (basophil); LIHC cis rs561341 0.883 rs4795661 chr17:30201774 T/A cg13647721 chr17:30228624 UTP6 -0.74 -7.1 -0.36 7.45e-12 Hip circumference adjusted for BMI; LIHC cis rs1008375 1.000 rs11724495 chr4:17621310 G/A cg04450456 chr4:17643702 FAM184B 0.34 5.79 0.3 1.63e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.94 18.73 0.71 2.27e-54 Height; LIHC cis rs919433 0.680 rs7590010 chr2:198400668 C/T cg10820045 chr2:198174542 NA 0.49 7.78 0.39 8.43e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.68 0.57 1.87e-30 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs2250719 chr1:231486208 G/A cg06096015 chr1:231504339 EGLN1 0.5 9.35 0.45 1.21e-18 Hemoglobin concentration; LIHC trans rs859980 0.514 rs9386402 chr6:104519786 C/T cg22481606 chr17:56429567 SUPT4H1 0.43 6.6 0.34 1.52e-10 Tourette's syndrome or obsessive-compulsive disorder; LIHC cis rs9942416 0.660 rs10462356 chr5:74987108 C/T cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs754466 0.580 rs2579178 chr10:79529215 A/G cg17075019 chr10:79541650 NA 0.76 11.69 0.53 8.69e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7131987 0.650 rs67146951 chr12:29450553 C/A cg16970926 chr12:29381810 FAR2 0.27 5.75 0.3 1.94e-8 QT interval; LIHC cis rs1144333 0.655 rs76794487 chr1:76384055 G/A cg22875332 chr1:76189707 ACADM 0.41 6.16 0.32 2.05e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs9354352 0.935 rs7766730 chr6:66697003 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.6 9.66 0.46 1.08e-19 Initial pursuit acceleration in psychotic disorders; LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg04013166 chr16:89971882 TCF25 0.64 8.78 0.43 7.74e-17 Skin colour saturation; LIHC cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg12386194 chr3:101231763 SENP7 0.47 7.01 0.35 1.25e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs9457247 0.935 rs401260 chr6:167405888 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC cis rs7617773 0.539 rs1471217 chr3:48384895 A/C cg11946769 chr3:48343235 NME6 0.56 6.8 0.35 4.63e-11 Coronary artery disease; LIHC cis rs7572733 0.576 rs1368989 chr2:198937082 T/C cg00792783 chr2:198669748 PLCL1 0.42 5.99 0.31 5.18e-9 Dermatomyositis; LIHC cis rs365132 0.715 rs181330 chr5:176404962 A/G cg16309518 chr5:176445507 NA -0.53 -9.96 -0.47 1.06e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg11644478 chr21:40555479 PSMG1 -0.38 -6.06 -0.31 3.5e-9 Menarche (age at onset); LIHC cis rs61712019 0.679 rs11126610 chr2:77714036 C/G cg11252801 chr2:77748917 LRRTM4 0.55 7.61 0.38 2.76e-13 Schizophrenia; LIHC cis rs712039 0.617 rs853201 chr17:35804187 C/A cg16670864 chr17:35848621 DUSP14 0.34 5.73 0.3 2.21e-8 Tuberculosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12191964 chr2:43823338 THADA -0.42 -6.37 -0.33 6.06e-10 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08779779 chr2:200322566 SATB2 -0.45 -6.24 -0.32 1.27e-9 Pancreatic cancer; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.76 0.39 1e-13 Prudent dietary pattern; LIHC cis rs8072100 0.676 rs9905308 chr17:45409386 T/A cg08085267 chr17:45401833 C17orf57 -0.73 -12.41 -0.56 1.96e-29 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs1005277 0.602 rs2504142 chr10:38383793 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs473651 0.935 rs541013 chr2:239336492 G/A cg21699342 chr2:239360505 ASB1 0.34 6.6 0.34 1.6e-10 Multiple system atrophy; LIHC cis rs3204270 0.759 rs8065104 chr17:79672605 G/A cg18367735 chr17:79674897 NA 0.72 8.44 0.42 9.1e-16 Dental caries; LIHC cis rs7927771 0.826 rs7925389 chr11:47466790 A/T cg18512352 chr11:47633146 NA -0.25 -5.78 -0.3 1.71e-8 Subjective well-being; LIHC cis rs74544699 1.000 rs585778 chr4:74779005 G/T cg02530824 chr4:74847766 PF4 0.54 6.2 0.32 1.66e-9 Growth-regulated protein alpha levels; LIHC cis rs8180040 0.726 rs7628747 chr3:47001990 A/T cg16586182 chr3:47516702 SCAP -0.45 -8.05 -0.4 1.36e-14 Colorectal cancer; LIHC cis rs8062405 1.000 rs4451951 chr16:28836205 T/C cg00204512 chr16:28754710 NA 0.35 6.42 0.33 4.5e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg06634786 chr22:41940651 POLR3H -0.76 -8.32 -0.41 2.14e-15 Vitiligo; LIHC cis rs11958404 0.932 rs72816588 chr5:157434390 C/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs1008375 0.932 rs3846356 chr4:17614176 C/T cg16339924 chr4:17578868 LAP3 0.42 5.83 0.3 1.27e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg24846343 chr22:24311635 DDTL 0.59 10.81 0.5 1.25e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7927592 0.673 rs498782 chr11:68275851 A/G cg16797656 chr11:68205561 LRP5 0.52 9.22 0.45 3.21e-18 Total body bone mineral density; LIHC cis rs10504073 0.584 rs4873304 chr8:49922733 G/A cg00325661 chr8:49890786 NA 0.39 9.53 0.46 2.97e-19 Blood metabolite ratios; LIHC cis rs4319547 0.695 rs12314643 chr12:122917423 C/T cg23029597 chr12:123009494 RSRC2 -0.52 -7.28 -0.37 2.27e-12 Body mass index; LIHC cis rs4319547 0.695 rs10734915 chr12:122873408 A/C cg05707623 chr12:122985044 ZCCHC8 -0.52 -6.89 -0.35 2.67e-11 Body mass index; LIHC cis rs1949733 0.701 rs2631754 chr4:8449233 A/G cg11789530 chr4:8429930 ACOX3 0.75 10.91 0.51 5.57e-24 Response to antineoplastic agents; LIHC trans rs1814175 0.781 rs28681334 chr11:50051177 C/T cg03929089 chr4:120376271 NA -0.89 -18.71 -0.71 2.82e-54 Height; LIHC trans rs1005277 0.579 rs1780116 chr10:38526621 C/T cg27523141 chr10:43048294 ZNF37B 0.38 6.36 0.33 6.38e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6912958 0.703 rs12207825 chr6:88098292 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.39 7.84 0.39 5.92e-14 Monocyte percentage of white cells; LIHC cis rs9640161 0.783 rs1132261 chr7:150059987 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.52 -0.42 5.1e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs12702595 1.000 rs12702595 chr7:7259270 C/A cg04827551 chr7:7268805 C1GALT1 0.36 6.6 0.34 1.61e-10 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs28374715 0.578 rs7169543 chr15:41620405 T/C cg18705301 chr15:41695430 NDUFAF1 -1.21 -16.78 -0.67 1.55e-46 Ulcerative colitis; LIHC cis rs12210905 0.800 rs12201890 chr6:26662626 A/C cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Hip circumference adjusted for BMI; LIHC cis rs10791097 0.653 rs11222362 chr11:130731425 T/C cg12179176 chr11:130786555 SNX19 0.73 11.66 0.53 1.11e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7633770 0.786 rs1520489 chr3:46677519 A/G cg11219411 chr3:46661640 NA -0.44 -7.87 -0.39 4.64e-14 Coronary artery disease; LIHC cis rs933688 1.000 rs6869717 chr5:90694797 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.42 0.66 4.33e-45 Smoking behavior; LIHC cis rs7523273 0.626 rs2466572 chr1:207934487 A/C cg22525895 chr1:207977042 MIR29B2 0.64 7.42 0.37 9.11e-13 Schizophrenia; LIHC cis rs992157 0.835 rs2271543 chr2:219142491 C/T cg00012203 chr2:219082015 ARPC2 -0.82 -13.09 -0.58 5.11e-32 Colorectal cancer; LIHC cis rs12950390 0.853 rs4793647 chr17:45854090 G/C cg03474202 chr17:45855739 NA -0.34 -5.97 -0.31 6.05e-9 IgG glycosylation; LIHC cis rs11030122 0.673 rs4910597 chr11:4094923 G/A cg18678763 chr11:4115507 RRM1 -0.58 -8.62 -0.42 2.46e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs3768617 0.528 rs4651144 chr1:183097421 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.57e-22 Fuchs's corneal dystrophy; LIHC cis rs2841277 0.708 rs10083490 chr14:105402418 A/G cg14403583 chr14:105418241 AHNAK2 0.21 5.72 0.3 2.34e-8 Rheumatoid arthritis; LIHC cis rs9858542 0.953 rs9821311 chr3:49543656 C/T cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs3859192 0.599 rs2270401 chr17:38176256 A/T cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.82 0.65 1.11e-42 White blood cell count; LIHC cis rs7249142 0.573 rs2238668 chr19:19282597 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -6.99 -0.35 1.48e-11 IgG glycosylation; LIHC trans rs56341938 0.757 rs1420465 chr3:168715138 C/G cg03582793 chr3:141162020 ZBTB38 -0.26 -6.34 -0.32 7.32e-10 Lung function (FEV1/FVC); LIHC trans rs61931739 0.500 rs11053223 chr12:34481947 T/A cg26384229 chr12:38710491 ALG10B 0.8 9.89 0.47 1.85e-20 Morning vs. evening chronotype; LIHC cis rs1448094 0.512 rs2405632 chr12:86252456 A/G cg02569458 chr12:86230093 RASSF9 0.46 6.19 0.32 1.77e-9 Major depressive disorder; LIHC cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg02187348 chr16:89574699 SPG7 0.66 10.66 0.5 4.2e-23 Multiple myeloma (IgH translocation); LIHC cis rs4824093 0.610 rs7410773 chr22:50313727 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -5.71 -0.3 2.4e-8 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs6430585 0.702 rs73958637 chr2:136546927 C/T cg07169764 chr2:136633963 MCM6 1.16 17.26 0.68 1.87e-48 Corneal structure; LIHC cis rs7927771 0.725 rs11039265 chr11:47523214 C/A cg20135002 chr11:47629003 NA -0.56 -9.7 -0.46 8.06e-20 Subjective well-being; LIHC cis rs2072499 0.966 rs2842864 chr1:156159217 G/A cg25208724 chr1:156163844 SLC25A44 0.94 15.95 0.65 3.43e-43 Testicular germ cell tumor; LIHC cis rs6429082 0.715 rs2153204 chr1:235580382 A/G cg26050004 chr1:235667680 B3GALNT2 -0.49 -7.42 -0.37 9.23e-13 Adiposity; LIHC trans rs561341 0.739 rs7213369 chr17:30211878 G/A cg20587970 chr11:113659929 NA 0.54 6.88 0.35 2.9100000000000002e-11 Hip circumference adjusted for BMI; LIHC cis rs11719291 0.667 rs9877542 chr3:48748545 C/T cg07636037 chr3:49044803 WDR6 -0.73 -7.78 -0.39 8.38e-14 Cognitive function; LIHC cis rs36051895 0.659 rs72699590 chr9:5041690 C/G cg02405213 chr9:5042618 JAK2 -0.72 -12.59 -0.56 4.13e-30 Pediatric autoimmune diseases; LIHC cis rs9790314 1.000 rs7653233 chr3:160992033 G/A cg03342759 chr3:160939853 NMD3 -0.78 -11.07 -0.51 1.46e-24 Morning vs. evening chronotype; LIHC cis rs7772486 0.875 rs9403764 chr6:146360582 G/A cg05347473 chr6:146136440 FBXO30 0.37 6.12 0.31 2.5e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg12310025 chr6:25882481 NA -0.73 -9.13 -0.44 6.31e-18 Intelligence (multi-trait analysis); LIHC cis rs1538970 0.962 rs2153607 chr1:45813820 G/A cg24296786 chr1:45957014 TESK2 -0.5 -7.48 -0.38 6.21e-13 Platelet count; LIHC cis rs2153535 0.623 rs2152346 chr6:8454652 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.23e-16 Motion sickness; LIHC cis rs644799 0.862 rs1150361 chr11:95633805 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.44 5.94 0.31 7.07e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs8117834 0.574 rs1079777 chr20:8084404 C/T cg00593689 chr4:53575888 NA 0.38 6.54 0.33 2.22e-10 Chronic kidney disease; LIHC trans rs9929218 0.529 rs11075694 chr16:68730366 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.89 19.76 0.73 1.68e-58 Colorectal cancer; LIHC cis rs13217239 0.646 rs10946898 chr6:27003884 T/C cg12292205 chr6:26970375 C6orf41 0.44 7.64 0.38 2.25e-13 Schizophrenia; LIHC cis rs6570726 0.791 rs9403729 chr6:145907007 C/T cg13319975 chr6:146136371 FBXO30 -0.42 -6.72 -0.34 7.71e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11122272 0.735 rs2808580 chr1:231509259 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs6088580 0.524 rs6088567 chr20:33263872 A/T cg07148914 chr20:33460835 GGT7 -0.51 -7.19 -0.36 4.11e-12 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg11764359 chr7:65958608 NA 0.58 6.01 0.31 4.64e-9 Diabetic kidney disease; LIHC cis rs1385374 0.563 rs12299194 chr12:129264838 A/G cg09035930 chr12:129282057 SLC15A4 -0.48 -5.86 -0.3 1.11e-8 Systemic lupus erythematosus; LIHC cis rs2070488 0.804 rs13094715 chr3:38504430 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.59 0.56 4.07e-30 Electrocardiographic conduction measures; LIHC cis rs6904897 0.563 rs6569976 chr6:135224753 A/C cg22676075 chr6:135203613 NA 0.59 10.39 0.49 3.68e-22 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs738321 0.690 rs11570750 chr22:38513138 G/A cg25457927 chr22:38595422 NA -0.29 -6.46 -0.33 3.53e-10 Breast cancer; LIHC cis rs7131987 0.934 rs2216854 chr12:29423460 G/A cg12903224 chr12:29470962 FAR2 -0.37 -5.96 -0.31 6.28e-9 QT interval; LIHC cis rs919433 0.680 rs8539 chr2:198362018 A/G cg03934865 chr2:198174659 NA 0.45 6.97 0.35 1.65e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs11098499 0.908 rs71614449 chr4:120387055 C/T cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs7100689 0.754 rs1934695 chr10:82125230 T/C cg01528321 chr10:82214614 TSPAN14 0.87 11.84 0.54 2.43e-27 Post bronchodilator FEV1; LIHC cis rs9916302 0.904 rs35285898 chr17:37555872 A/C cg07936489 chr17:37558343 FBXL20 0.85 13.54 0.59 1.01e-33 Glomerular filtration rate (creatinine); LIHC cis rs10463316 0.855 rs13359064 chr5:150765575 G/A cg03212797 chr5:150827313 SLC36A1 -0.44 -6.6 -0.34 1.54e-10 Metabolite levels (Pyroglutamine); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg07614371 chr15:38746870 FAM98B -0.42 -6.29 -0.32 9.76e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg10360323 chr17:41437877 NA 0.4 5.98 0.31 5.76e-9 Menopause (age at onset); LIHC cis rs2204008 0.754 rs11181244 chr12:38302454 T/C cg26384229 chr12:38710491 ALG10B 0.6 8.21 0.41 4.57e-15 Bladder cancer; LIHC cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 3.96e-13 Electroencephalogram traits; LIHC cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg10360323 chr17:41437877 NA 0.39 5.75 0.3 1.98e-8 Menopause (age at onset); LIHC trans rs11098499 0.618 rs28491261 chr4:120294900 C/A cg25214090 chr10:38739885 LOC399744 0.56 8.64 0.42 2.2e-16 Corneal astigmatism; LIHC cis rs10508774 1.000 rs72795564 chr10:32888300 T/A cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs12368653 0.840 rs10877020 chr12:58188014 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.54 -7.61 -0.38 2.76e-13 Multiple sclerosis; LIHC cis rs4294134 0.832 rs11768962 chr7:135254692 C/T cg20392616 chr7:135392013 SLC13A4 -0.37 -5.88 -0.3 9.51e-9 Paget's disease; LIHC cis rs2274273 0.905 rs2147961 chr14:55585381 T/C cg04306507 chr14:55594613 LGALS3 0.32 6.21 0.32 1.49e-9 Protein biomarker; LIHC cis rs4713118 0.869 rs4713121 chr6:27722064 T/C cg20933634 chr6:27740509 NA 0.45 5.85 0.3 1.15e-8 Parkinson's disease; LIHC cis rs10089 0.951 rs1864923 chr5:127420843 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.74 0.34 6.77e-11 Ileal carcinoids; LIHC cis rs5769765 1.000 rs4597652 chr22:50270570 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC trans rs11098499 0.722 rs17595727 chr4:120262074 C/T cg25214090 chr10:38739885 LOC399744 -0.45 -7.3 -0.37 2e-12 Corneal astigmatism; LIHC cis rs1691799 0.899 rs1168295 chr12:66734151 G/C cg16791601 chr12:66731901 HELB -0.57 -13.93 -0.6 2.98e-35 White blood cell count (basophil); LIHC cis rs9486719 1.000 rs2142653 chr6:96871520 C/A cg06623918 chr6:96969491 KIAA0776 0.74 7.29 0.37 2.22e-12 Migraine;Coronary artery disease; LIHC cis rs10789491 0.953 rs11211337 chr1:47133811 T/C cg15501359 chr1:47185051 KIAA0494 0.76 10.87 0.51 7.95e-24 Response to hepatitis C treatment; LIHC cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg05552183 chr6:42928497 GNMT 0.83 12.16 0.55 1.59e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs16958440 0.867 rs28578518 chr18:44687548 A/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs3849570 0.961 rs3772912 chr3:81698481 A/G cg07356753 chr3:81810745 GBE1 -0.59 -8.25 -0.41 3.39e-15 Waist circumference;Body mass index; LIHC cis rs6061231 1.000 rs11908473 chr20:60957770 C/G cg06026331 chr20:60912101 LAMA5 0.41 5.98 0.31 5.65e-9 Colorectal cancer; LIHC cis rs10493773 0.609 rs11161664 chr1:86185379 C/T cg17807903 chr1:86174739 ZNHIT6 -0.6 -11.66 -0.53 1.12e-26 Urate levels in overweight individuals; LIHC cis rs7523273 0.606 rs2796263 chr1:207915978 T/C cg22525895 chr1:207977042 MIR29B2 0.66 10.7 0.5 3.06e-23 Schizophrenia; LIHC cis rs4788570 0.667 rs9302630 chr16:71789529 A/C cg06353428 chr16:71660113 MARVELD3 1.38 14.61 0.62 6.7e-38 Intelligence (multi-trait analysis); LIHC cis rs950169 0.922 rs62029585 chr15:84951874 C/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.45 0.42 8.25e-16 Schizophrenia; LIHC cis rs2832191 0.671 rs2832212 chr21:30511417 G/A cg24692254 chr21:30365293 RNF160 -0.42 -6.65 -0.34 1.19e-10 Dental caries; LIHC cis rs1005277 0.505 rs200939 chr10:38139483 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.5 -0.46 3.74e-19 Extrinsic epigenetic age acceleration; LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg12064134 chr16:90016061 DEF8 -0.43 -5.89 -0.3 9.2e-9 Skin colour saturation; LIHC cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg11279151 chr3:101281821 RG9MTD1 -0.51 -7.43 -0.37 8.88e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs56091001 0.528 rs9616387 chr22:50313219 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.81 -6.63 -0.34 1.29e-10 Acne (severe); LIHC cis rs7572733 0.534 rs10931794 chr2:198776140 C/T cg10820045 chr2:198174542 NA -0.47 -7.2 -0.36 3.92e-12 Dermatomyositis; LIHC cis rs116095464 0.867 rs10074958 chr5:230828 C/T cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs922107 0.967 rs922105 chr1:90025657 C/T cg15422784 chr1:90023713 LRRC8B 0.5 8.07 0.4 1.24e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs4631830 0.720 rs2012677 chr10:51504797 T/A cg16070123 chr10:51489643 NA -0.38 -6.03 -0.31 4.34e-9 Prostate-specific antigen levels; LIHC cis rs7589728 0.688 rs76734941 chr2:88530454 T/C cg04511125 chr2:88470314 THNSL2 0.79 6.89 0.35 2.76e-11 Plasma clusterin levels; LIHC trans rs9929218 1.000 rs4500718 chr16:68754312 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.48 -0.46 4.39e-19 Colorectal cancer; LIHC cis rs7312933 0.558 rs1051453 chr12:42852217 C/T cg01256987 chr12:42539512 GXYLT1 -0.36 -5.96 -0.31 6.23e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg04013166 chr16:89971882 TCF25 0.61 7.92 0.39 3.34e-14 Skin colour saturation; LIHC cis rs716804 0.740 rs55933041 chr11:10263554 C/T cg01453529 chr11:10209919 SBF2 -0.29 -5.86 -0.3 1.12e-8 Neuroticism; LIHC cis rs10463316 0.862 rs10071166 chr5:150768795 T/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.46 -0.33 3.62e-10 Metabolite levels (Pyroglutamine); LIHC cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg10360323 chr17:41437877 NA 0.4 5.96 0.31 6.4e-9 Menopause (age at onset); LIHC cis rs1059312 1.000 rs7970815 chr12:129288366 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.71 -13.98 -0.6 1.99e-35 Systemic lupus erythematosus; LIHC cis rs12701220 0.901 rs12701710 chr7:1090396 A/G cg16145915 chr7:1198662 ZFAND2A 0.3 5.91 0.3 8.05e-9 Bronchopulmonary dysplasia; LIHC cis rs4819052 0.851 rs28622522 chr21:46676599 G/T cg22633049 chr21:46681294 NA -0.36 -6.14 -0.32 2.31e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2836950 0.501 rs11702505 chr21:40700614 G/T cg06238570 chr21:40685208 BRWD1 -0.46 -7.47 -0.37 6.88e-13 Menarche (age at onset); LIHC trans rs6934970 1.000 rs12201997 chr6:113098589 C/T cg09308777 chr6:169852575 NA 0.62 6.16 0.32 2.08e-9 Bipolar disorder (body mass index interaction); LIHC cis rs2404602 1.000 rs12148786 chr15:76800362 A/G cg03037974 chr15:76606532 NA 0.72 13.93 0.6 2.96e-35 Blood metabolite levels; LIHC cis rs4665809 0.838 rs6546780 chr2:26352857 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.72 -0.43 1.26e-16 Gut microbiome composition (summer); LIHC cis rs6121246 0.821 rs6119718 chr20:30331074 A/G cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC cis rs2404602 0.647 rs11072616 chr15:76985269 T/C cg03037974 chr15:76606532 NA -0.59 -10.13 -0.48 2.91e-21 Blood metabolite levels; LIHC trans rs17685 0.753 rs11982200 chr7:75714883 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs208515 0.525 rs12193034 chr6:66677866 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.79 0.43 7.58e-17 Exhaled nitric oxide levels; LIHC cis rs8141529 0.764 rs5752809 chr22:29225500 G/A cg15103426 chr22:29168792 CCDC117 0.67 11.37 0.52 1.29e-25 Lymphocyte counts; LIHC cis rs7584330 0.554 rs74001399 chr2:238445440 G/A cg08992911 chr2:238395768 MLPH 0.49 5.96 0.31 6.24e-9 Prostate cancer; LIHC cis rs6545883 0.929 rs1838978 chr2:61540923 T/C cg14146966 chr2:61757674 XPO1 -0.43 -7.34 -0.37 1.53e-12 Tuberculosis; LIHC trans rs10411161 0.702 rs8113685 chr19:52383890 C/T cg22319618 chr22:45562946 NUP50 -0.6 -8.17 -0.4 6.12e-15 Breast cancer; LIHC cis rs9918079 0.560 rs4557256 chr4:15626647 A/C cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.84 -0.3 1.21e-8 Obesity-related traits; LIHC cis rs6840360 0.554 rs58751443 chr4:152709905 A/G cg22705602 chr4:152727874 NA -0.4 -8.54 -0.42 4.44e-16 Intelligence (multi-trait analysis); LIHC cis rs7829975 0.564 rs2921060 chr8:8317817 G/T cg14343924 chr8:8086146 FLJ10661 -0.45 -5.77 -0.3 1.8e-8 Mood instability; LIHC trans rs12478296 1.000 rs56323081 chr2:243040807 A/G cg01596870 chr19:55963115 NA -0.61 -7.22 -0.36 3.5e-12 Obesity-related traits; LIHC cis rs2228479 0.850 rs11641552 chr16:89838700 C/A cg19635926 chr16:89946313 TCF25 0.51 6.5 0.33 2.78e-10 Skin colour saturation; LIHC cis rs9715521 0.677 rs11944208 chr4:59860652 G/A cg11281224 chr4:60001000 NA -0.34 -6.29 -0.32 9.69e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs17345786 0.906 rs11708616 chr3:101231731 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.55 7.52 0.38 4.81e-13 Colonoscopy-negative controls vs population controls; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15087520 chr3:187871600 LPP 0.43 6.05 0.31 3.87e-9 Pancreatic cancer; LIHC cis rs7587476 0.601 rs17489363 chr2:215674341 A/G cg04530015 chr2:215796436 ABCA12 0.46 7.7 0.38 1.51e-13 Neuroblastoma; LIHC cis rs8180040 0.739 rs4683320 chr3:47152992 C/T cg16586182 chr3:47516702 SCAP -0.52 -9.52 -0.46 3.26e-19 Colorectal cancer; LIHC cis rs7131987 0.650 rs3782509 chr12:29453778 G/A cg00204748 chr12:29376779 FAR2 0.37 6.91 0.35 2.36e-11 QT interval; LIHC cis rs9326248 0.954 rs521171 chr11:117064693 C/G cg15534755 chr11:117069859 TAGLN 0.39 6.67 0.34 1e-10 Blood protein levels; LIHC trans rs2727020 0.521 rs4980445 chr11:49570183 C/T cg15704280 chr7:45808275 SEPT13 -0.79 -12.03 -0.55 4.69e-28 Coronary artery disease; LIHC cis rs6840360 0.967 rs7695162 chr4:152510541 G/A cg22705602 chr4:152727874 NA -0.29 -6.08 -0.31 3.18e-9 Intelligence (multi-trait analysis); LIHC trans rs116095464 0.558 rs9688045 chr5:254035 T/C cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs11711311 0.955 rs3796254 chr3:113380332 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.38 6.39 0.33 5.42e-10 IgG glycosylation; LIHC cis rs79976124 1.000 rs79976124 chr6:66618657 G/A cg07460842 chr6:66804631 NA 0.61 6.15 0.32 2.15e-9 Type 2 diabetes; LIHC cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg00684032 chr4:1343700 KIAA1530 0.5 7.19 0.36 4.15e-12 Obesity-related traits; LIHC cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg16325326 chr1:53192061 ZYG11B -0.5 -8.78 -0.43 8.15e-17 Monocyte count; LIHC cis rs918629 0.567 rs2270554 chr5:95246134 G/T cg10483112 chr5:95245456 ELL2 0.37 6.98 0.35 1.52e-11 IgG glycosylation; LIHC cis rs2153535 0.580 rs2152348 chr6:8474301 C/A cg07606381 chr6:8435919 SLC35B3 0.8 12.07 0.55 3.41e-28 Motion sickness; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg00035636 chr13:21900591 NA 0.38 6.53 0.33 2.33e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs16866061 0.515 rs114968850 chr2:225352461 C/G cg12698349 chr2:225449008 CUL3 0.88 20.03 0.73 1.35e-59 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs1008375 1.000 rs2315561 chr4:17679695 C/T cg02297831 chr4:17616191 MED28 0.42 6.81 0.35 4.43e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs796364 0.616 rs2103094 chr2:200687954 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.16 0.32 2.03e-9 Schizophrenia; LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs2455601 0.786 rs3751064 chr11:8958903 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -6.39 -0.33 5.42e-10 Schizophrenia; LIHC cis rs11758351 0.660 rs16891455 chr6:26230485 G/A cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs2033711 0.870 rs3764534 chr19:58929136 G/A cg26874164 chr19:58962979 ZNF324B 0.43 5.94 0.31 6.99e-9 Uric acid clearance; LIHC cis rs2836950 0.545 rs8132143 chr21:40584258 A/T cg11890956 chr21:40555474 PSMG1 -0.47 -7.81 -0.39 7e-14 Menarche (age at onset); LIHC cis rs9359856 0.662 rs1179904 chr6:90322573 A/G cg13799429 chr6:90582589 CASP8AP2 0.65 8.07 0.4 1.18e-14 Bipolar disorder; LIHC cis rs11724804 0.532 rs7657611 chr4:880558 G/C cg23939001 chr4:940644 TMEM175 0.48 7.37 0.37 1.27e-12 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC trans rs1814175 0.765 rs11493326 chr11:50018063 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.1 -0.78 8.79e-72 Height; LIHC cis rs6933660 0.745 rs9322320 chr6:151751908 C/G cg10883421 chr6:151773342 RMND1;C6orf211 0.6 10.05 0.48 5.63e-21 Menarche (age at onset); LIHC trans rs9641123 0.639 rs2528542 chr7:93266368 T/C cg09745688 chr16:2908918 PRSS22 -0.37 -6.52 -0.33 2.58e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs2302190 0.882 rs9911609 chr17:56673087 T/C cg12560992 chr17:57184187 TRIM37 0.69 8.91 0.43 3.17e-17 Vitamin D levels; LIHC cis rs9811920 0.609 rs4244713 chr3:99679584 T/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.15 0.36 5.37e-12 Axial length; LIHC cis rs4474465 0.920 rs4945285 chr11:78221698 C/T cg02023728 chr11:77925099 USP35 -0.33 -5.84 -0.3 1.2e-8 Alzheimer's disease (survival time); LIHC cis rs57920188 0.535 rs4295855 chr1:4094993 C/T cg20703997 chr1:4087676 NA 0.55 6.47 0.33 3.46e-10 Interleukin-17 levels; LIHC cis rs7520050 0.966 rs785520 chr1:46568836 T/C cg03146154 chr1:46216737 IPP -0.37 -6.17 -0.32 1.96e-9 Red blood cell count;Reticulocyte count; LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.86e-9 Total body bone mineral density; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25437947 chr8:17941982 ASAH1 0.45 6.2 0.32 1.59e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs2832191 0.716 rs1984012 chr21:30392472 T/C cg24692254 chr21:30365293 RNF160 0.87 15.88 0.65 6.07e-43 Dental caries; LIHC cis rs3823572 0.542 rs62470445 chr7:133630961 T/C cg03336402 chr7:133662267 EXOC4 0.47 5.84 0.3 1.22e-8 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.550 rs12994270 chr2:136518103 T/A cg07169764 chr2:136633963 MCM6 -0.7 -10.19 -0.48 1.77e-21 Mosquito bite size; LIHC cis rs2070488 0.965 rs35553573 chr3:38441439 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.76 0.65 1.97e-42 Electrocardiographic conduction measures; LIHC trans rs4714291 0.832 rs2984431 chr6:39980900 T/A cg02267698 chr19:7991119 CTXN1 -0.39 -6.51 -0.33 2.68e-10 Strep throat; LIHC cis rs7582720 1.000 rs72932776 chr2:203688300 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.83 0.3 1.32e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs763121 0.853 rs2413545 chr22:39092524 C/T cg14440974 chr22:39074834 NA -0.46 -7.35 -0.37 1.52e-12 Menopause (age at onset); LIHC cis rs41271473 0.526 rs12136157 chr1:228703236 T/C cg10167378 chr1:228756711 NA 0.65 6.82 0.35 4.18e-11 Chronic lymphocytic leukemia; LIHC cis rs9326248 0.954 rs10790177 chr11:117048417 A/G cg26566898 chr11:117069891 TAGLN 0.48 7.71 0.39 1.34e-13 Blood protein levels; LIHC cis rs6060717 0.610 rs2794383 chr20:34615152 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -7.99 -0.4 2.14e-14 Hip circumference adjusted for BMI; LIHC trans rs1005277 0.563 rs2505216 chr10:38482830 T/C cg27523141 chr10:43048294 ZNF37B 0.38 6.34 0.32 7.24e-10 Extrinsic epigenetic age acceleration; LIHC cis rs8072100 0.905 rs8078686 chr17:45735706 T/C cg19378624 chr17:45501242 LOC100272146;C17orf57 0.4 6.23 0.32 1.36e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs826838 0.616 rs4619214 chr12:38614704 C/A cg26384229 chr12:38710491 ALG10B 0.43 6.49 0.33 2.93e-10 Heart rate; LIHC cis rs11098499 1.000 rs3749591 chr4:120214030 T/G cg09307838 chr4:120376055 NA 0.75 11.16 0.52 7.39e-25 Corneal astigmatism; LIHC cis rs6570726 0.791 rs13202312 chr6:145913093 T/G cg13319975 chr6:146136371 FBXO30 -0.42 -6.58 -0.34 1.76e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs8060686 0.545 rs117751972 chr16:68171968 C/T cg05110241 chr16:68378359 PRMT7 -0.63 -6.85 -0.35 3.34e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs11031096 0.655 rs1372806 chr11:4212308 C/T cg18678763 chr11:4115507 RRM1 -0.4 -5.91 -0.3 8.4e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg26677602 chr1:167035992 GPA33 0.43 6.77 0.34 5.61e-11 Calcium levels; LIHC cis rs11690935 0.877 rs72890834 chr2:172835802 G/T cg13550731 chr2:172543902 DYNC1I2 -0.92 -16.42 -0.66 4.18e-45 Schizophrenia; LIHC cis rs9443189 1.000 rs3822957 chr6:76607280 A/G cg01950844 chr6:76311363 SENP6 -0.49 -6.23 -0.32 1.4e-9 Prostate cancer; LIHC cis rs9522267 0.535 rs9522284 chr13:112229343 C/T cg10483660 chr13:112241077 NA -0.22 -5.97 -0.31 5.95e-9 Hepatitis; LIHC cis rs9837602 0.507 rs1718244 chr3:99512608 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.42 -5.86 -0.3 1.09e-8 Breast cancer; LIHC cis rs778371 1.000 rs778371 chr2:233743109 A/G cg08000102 chr2:233561755 GIGYF2 -0.75 -9.03 -0.44 1.26e-17 Schizophrenia; LIHC cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.27e-19 Initial pursuit acceleration; LIHC cis rs28374715 0.681 rs7168307 chr15:41620534 A/G cg18705301 chr15:41695430 NDUFAF1 -1.02 -14.24 -0.61 1.8e-36 Ulcerative colitis; LIHC cis rs6430585 0.583 rs59213715 chr2:136646582 A/C cg15123519 chr2:136567270 LCT -0.37 -5.75 -0.3 1.98e-8 Corneal structure; LIHC cis rs2834188 1.000 rs13050445 chr21:34703597 C/T cg14352951 chr21:34696688 IFNAR1 -0.51 -6.73 -0.34 7.03e-11 Narcolepsy; LIHC cis rs875971 0.862 rs6945775 chr7:65968974 G/A cg18876405 chr7:65276391 NA 0.35 6.45 0.33 3.83e-10 Aortic root size; LIHC cis rs7131987 0.903 rs67517901 chr12:29421346 A/G cg16970926 chr12:29381810 FAR2 0.28 5.94 0.31 6.84e-9 QT interval; LIHC cis rs17685 0.712 rs9800948 chr7:75810473 A/G cg16684958 chr7:75615977 POR 0.47 7.84 0.39 5.69e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4332037 0.530 rs62434669 chr7:1866946 G/A cg23422044 chr7:1970798 MAD1L1 -0.52 -5.8 -0.3 1.48e-8 Bipolar disorder; LIHC cis rs68170813 0.559 rs76167266 chr7:106900664 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs8067354 0.540 rs12600680 chr17:58037374 T/C cg13753209 chr17:57696993 CLTC 0.71 10.58 0.5 8.01e-23 Hemoglobin concentration; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg17178900 chr1:205818956 PM20D1 0.65 9.69 0.46 8.67e-20 Menarche (age at onset); LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg02398342 chr17:80708632 TBCD;FN3K -0.62 -10.33 -0.49 5.78e-22 Glycated hemoglobin levels; LIHC cis rs2228479 0.850 rs11649510 chr16:89851004 A/G cg00800038 chr16:89945340 TCF25 -0.6 -8.65 -0.42 2.09e-16 Skin colour saturation; LIHC cis rs6570726 0.846 rs9399559 chr6:145945778 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.5 0.53 4.37e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs11608355 0.515 rs11611011 chr12:109936948 C/T cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs11048434 0.761 rs2110190 chr12:9128289 A/C cg04155231 chr12:9217510 LOC144571 0.31 5.75 0.3 1.99e-8 Sjögren's syndrome; LIHC cis rs12908161 0.960 rs34452033 chr15:85221993 A/G cg17507749 chr15:85114479 UBE2QP1 0.68 7.75 0.39 1.03e-13 Schizophrenia; LIHC cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg16405210 chr4:1374714 KIAA1530 0.43 6.37 0.33 6.12e-10 Obesity-related traits; LIHC cis rs2839186 1.000 rs2839181 chr21:47685939 A/G cg00612595 chr21:47717864 NA -0.36 -5.93 -0.31 7.48e-9 Testicular germ cell tumor; LIHC cis rs7572733 0.534 rs770657 chr2:198674184 C/A cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.42e-11 Dermatomyositis; LIHC cis rs9811920 0.599 rs1688758 chr3:99539890 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.16 0.36 5.12e-12 Axial length; LIHC cis rs9549367 0.713 rs1755690 chr13:113824266 T/C cg18105134 chr13:113819100 PROZ 0.59 10.08 0.48 4.29e-21 Platelet distribution width; LIHC cis rs35955747 0.869 rs7286648 chr22:31539614 A/T cg22777020 chr22:31556080 RNF185 0.53 6.32 0.32 8.03e-10 Neutrophil count;Sum basophil neutrophil counts; LIHC cis rs17826219 0.636 rs8080829 chr17:29058730 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.96 0.35 1.71e-11 Body mass index; LIHC cis rs240764 0.817 rs240164 chr6:101044487 T/A cg09795085 chr6:101329169 ASCC3 0.5 6.75 0.34 6.2e-11 Neuroticism; LIHC cis rs62179067 0.708 rs11885227 chr2:179935847 G/A cg07532576 chr2:179544947 TTN 0.61 5.8 0.3 1.49e-8 Late-onset Alzheimer's disease; LIHC cis rs11971779 0.680 rs7795520 chr7:139079207 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.42e-21 Diisocyanate-induced asthma; LIHC cis rs9303401 1.000 rs7218362 chr17:56888299 A/G cg05425664 chr17:57184151 TRIM37 -0.53 -7.49 -0.38 6.06e-13 Cognitive test performance; LIHC cis rs8180040 0.966 rs807932 chr3:47354241 C/T cg27129171 chr3:47204927 SETD2 0.64 10.95 0.51 4.12e-24 Colorectal cancer; LIHC cis rs34245846 0.704 rs11264280 chr1:154862952 C/T cg06418219 chr1:154948305 SHC1;CKS1B 0.87 12.54 0.56 6.33e-30 Atrial fibrillation; LIHC trans rs7726839 0.574 rs72707007 chr5:661856 T/C cg25482853 chr8:67687455 SGK3 0.61 6.14 0.32 2.29e-9 Obesity-related traits; LIHC trans rs1994135 0.647 rs67243558 chr12:33695383 T/C cg26384229 chr12:38710491 ALG10B 0.49 6.57 0.33 1.85e-10 Resting heart rate; LIHC cis rs4243830 0.850 rs7552196 chr1:6590502 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.83 -10.14 -0.48 2.72e-21 Body mass index; LIHC cis rs3823572 0.564 rs2346274 chr7:133660841 G/A cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs2073300 0.609 rs56094936 chr20:23401586 G/A cg12062639 chr20:23401060 NAPB 1.05 13.93 0.6 2.88e-35 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17106184 1.000 rs57183177 chr1:51379945 A/G cg07174182 chr1:51127561 FAF1 -0.77 -7.84 -0.39 5.73e-14 Type 2 diabetes; LIHC cis rs892961 0.899 rs66749226 chr17:75412826 G/A cg05865280 chr17:75406074 SEPT9 0.64 13.1 0.58 4.87e-32 Airflow obstruction; LIHC cis rs1552244 0.882 rs36006511 chr3:10054191 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.63 -9.1 -0.44 7.75e-18 Alzheimer's disease; LIHC cis rs921968 0.541 rs642520 chr2:219423605 A/G cg02985541 chr2:219472218 PLCD4 -0.43 -7.22 -0.36 3.44e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs208520 0.955 rs12204033 chr6:67001525 T/C cg07460842 chr6:66804631 NA 0.66 7.07 0.36 8.62e-12 Exhaled nitric oxide output; LIHC cis rs4699052 0.893 rs4699058 chr4:104171321 T/A cg16532752 chr4:104119610 CENPE -0.39 -6.14 -0.32 2.23e-9 Testicular germ cell tumor; LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg06420487 chr17:61919686 SMARCD2 0.44 5.88 0.3 9.71e-9 Height; LIHC cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.66 0.46 1.13e-19 Bipolar disorder; LIHC cis rs2742417 0.603 rs2673055 chr3:45772772 G/A cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg14828511 chr1:107599125 PRMT6 -0.44 -6.25 -0.32 1.2e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9818758 0.556 rs9813813 chr3:49207093 T/A cg07636037 chr3:49044803 WDR6 -0.86 -7.19 -0.36 4.01e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg05697976 chr12:29376483 FAR2 0.34 6.91 0.35 2.39e-11 QT interval; LIHC cis rs9902453 0.874 rs11653805 chr17:28378276 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.02 0.44 1.38e-17 Platelet count; LIHC cis rs708547 0.671 rs1718863 chr4:57887586 G/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.45 6.59 0.34 1.63e-10 Response to bleomycin (chromatid breaks); LIHC cis rs10503871 0.526 rs67817462 chr8:30483031 C/T cg26383811 chr8:30366931 RBPMS 0.43 6.91 0.35 2.43e-11 Metabolite levels (X-11787); LIHC cis rs769267 0.930 rs892021 chr19:19613480 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.87 0.3 1.05e-8 Tonsillectomy; LIHC cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.1 17.12 0.68 6.77e-48 Gut microbiome composition (summer); LIHC cis rs600806 0.745 rs4246517 chr1:110007636 G/C cg16275483 chr1:110013120 SYPL2 -0.49 -6.18 -0.32 1.8e-9 Intelligence (multi-trait analysis); LIHC cis rs5769765 0.720 rs138820 chr22:50164078 A/G cg02269571 chr22:50332266 NA -0.48 -6.93 -0.35 2.12e-11 Schizophrenia; LIHC cis rs2072499 0.750 rs2241109 chr1:156173082 C/T cg25208724 chr1:156163844 SLC25A44 0.72 8.23 0.41 3.95e-15 Testicular germ cell tumor; LIHC cis rs6782228 0.585 rs6774515 chr3:128415878 C/T cg16766828 chr3:128327626 NA -0.38 -6.01 -0.31 4.71e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.77 -0.5 1.68e-23 Platelet count; LIHC cis rs1790761 0.667 rs1254123 chr11:67334812 T/C cg21734168 chr11:67353974 GSTP1 -0.26 -6.39 -0.33 5.56e-10 Mean corpuscular volume; LIHC cis rs798502 0.522 rs7790322 chr7:2830498 C/T cg18446336 chr7:2847575 GNA12 -0.36 -6.92 -0.35 2.22e-11 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Inflammatory bowel disease;Waist circumference adjusted for BMI in non-smokers;Ulcerative colitis;Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs6430585 0.583 rs79176913 chr2:136638113 C/A cg15123519 chr2:136567270 LCT -0.38 -6.14 -0.32 2.25e-9 Corneal structure; LIHC cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg19318889 chr4:1322082 MAEA 0.41 5.91 0.3 8.37e-9 Obesity-related traits; LIHC cis rs1577917 0.958 rs7747897 chr6:86647349 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.6 -0.5 7.13e-23 Response to antipsychotic treatment; LIHC cis rs929354 0.772 rs6459737 chr7:156975136 G/A cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs763121 0.886 rs1013339 chr22:38974680 C/T cg06022373 chr22:39101656 GTPBP1 0.72 14.71 0.62 2.66e-38 Menopause (age at onset); LIHC cis rs986417 0.748 rs1955691 chr14:61004128 G/A cg27398547 chr14:60952738 C14orf39 0.74 8.19 0.4 5.33e-15 Gut microbiota (bacterial taxa); LIHC cis rs7131987 0.845 rs2042511 chr12:29408780 C/T cg05697976 chr12:29376483 FAR2 0.31 6.38 0.33 5.76e-10 QT interval; LIHC cis rs12594515 1.000 rs11855509 chr15:45995474 C/T cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs2072499 0.966 rs2853643 chr1:156184831 G/A cg25208724 chr1:156163844 SLC25A44 0.87 13.62 0.59 4.87e-34 Testicular germ cell tumor; LIHC cis rs7131987 0.650 rs7311912 chr12:29475703 G/C cg14222432 chr12:29376421 FAR2 0.36 6.93 0.35 2.16e-11 QT interval; LIHC cis rs10256972 0.869 rs4720158 chr7:1040325 A/G cg07308232 chr7:1071921 C7orf50 -0.48 -8.13 -0.4 8.1e-15 Longevity;Endometriosis; LIHC cis rs60871478 0.787 rs4720928 chr7:808002 T/C cg27478167 chr7:817139 HEATR2 -0.41 -5.91 -0.3 8.35e-9 Cerebrospinal P-tau181p levels; LIHC cis rs10744422 1.000 rs4993320 chr12:123338092 T/C cg07706471 chr12:123319906 HIP1R -0.63 -8.28 -0.41 2.88e-15 Schizophrenia; LIHC cis rs9768139 0.733 rs12698209 chr7:158117595 A/G cg06219351 chr7:158114137 PTPRN2 0.2 5.73 0.3 2.15e-8 Calcium levels; LIHC cis rs1434579 0.865 rs12983645 chr19:44943239 A/G cg15540054 chr19:45004280 ZNF180 0.57 7.91 0.39 3.48e-14 Tuberculosis; LIHC cis rs909341 0.909 rs1151624 chr20:62369895 A/G cg03999872 chr20:62272968 STMN3 0.43 6.33 0.32 7.48e-10 Atopic dermatitis; LIHC cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg05590025 chr7:65112418 INTS4L2 -0.64 -6.98 -0.35 1.53e-11 Diabetic kidney disease; LIHC cis rs7208859 0.623 rs73269974 chr17:29112384 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10838687 0.800 rs4752977 chr11:47300429 T/C cg26139080 chr11:47293733 MADD -0.41 -5.76 -0.3 1.87e-8 Proinsulin levels; LIHC cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg17691542 chr6:26056736 HIST1H1C 0.39 5.9 0.3 8.77e-9 Height; LIHC cis rs11758351 1.000 rs75921373 chr6:26191843 C/T cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC cis rs7044106 0.708 rs1324472 chr9:123375110 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.66 0.5 4.38e-23 Hip circumference adjusted for BMI; LIHC cis rs9291683 0.595 rs13150928 chr4:10052961 G/T cg11266682 chr4:10021025 SLC2A9 0.35 7.34 0.37 1.56e-12 Bone mineral density; LIHC cis rs68170813 0.599 rs12533516 chr7:106937135 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs9308433 0.529 rs10465696 chr1:214499883 G/A cg06198575 chr1:214491504 SMYD2 0.55 5.86 0.3 1.08e-8 IgG glycosylation; LIHC cis rs7520050 0.966 rs6695809 chr1:46285461 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.07 0.31 3.38e-9 Red blood cell count;Reticulocyte count; LIHC cis rs875971 0.660 rs10281080 chr7:66042441 T/C cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs10752881 1.000 rs10737236 chr1:182988608 C/T ch.1.3577855R chr1:183094577 LAMC1 -0.52 -9.25 -0.45 2.51e-18 Colorectal cancer; LIHC trans rs75804782 0.521 rs55713398 chr2:239419933 A/G cg01134436 chr17:81009848 B3GNTL1 0.76 6.53 0.33 2.37e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.66 6.33 0.32 7.58e-10 Platelet count; LIHC cis rs12451471 0.637 rs7567 chr17:78093549 G/T cg06718696 chr17:78121285 EIF4A3 1.01 11.73 0.54 6.26e-27 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs10751667 0.961 rs6597951 chr11:991530 C/T cg06064525 chr11:970664 AP2A2 -0.49 -12.17 -0.55 1.5e-28 Alzheimer's disease (late onset); LIHC trans rs116095464 0.558 rs73031482 chr5:227594 G/A cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg14393609 chr7:65229607 NA -0.43 -6.4 -0.33 5.1e-10 Calcium levels; LIHC cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs4561483 0.831 rs8052900 chr16:11940390 T/C cg08843971 chr16:11963173 GSPT1 0.33 6.37 0.33 5.93e-10 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs7766852 chr6:8472417 C/T cg23788917 chr6:8435910 SLC35B3 0.58 8.19 0.4 5.41e-15 Motion sickness; LIHC cis rs2408955 0.568 rs12099462 chr12:48503104 T/C cg21466736 chr12:48725269 NA 0.63 9.2 0.45 3.67e-18 Glycated hemoglobin levels; LIHC cis rs6089829 0.962 rs4809462 chr20:61661560 A/G cg08564027 chr20:61660810 NA 0.39 7.61 0.38 2.68e-13 Prostate cancer (SNP x SNP interaction); LIHC trans rs4332037 0.906 rs6461009 chr7:1952139 T/C cg11693508 chr17:37793320 STARD3 -0.7 -7.56 -0.38 3.84e-13 Bipolar disorder; LIHC cis rs35110281 0.840 rs7276633 chr21:45078800 C/T cg01579765 chr21:45077557 HSF2BP -0.31 -5.97 -0.31 5.91e-9 Mean corpuscular volume; LIHC cis rs595982 0.527 rs73061658 chr19:49372376 G/C cg15549821 chr19:49342101 PLEKHA4 -0.69 -6.46 -0.33 3.5e-10 Red cell distribution width; LIHC cis rs10751667 0.666 rs7394427 chr11:970405 G/A cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs9303401 0.659 rs12946397 chr17:56769979 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs7208859 0.673 rs57432042 chr17:29241038 T/C cg14067834 chr17:29058358 SUZ12P 0.67 6.39 0.33 5.57e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1559088 0.895 rs1974784 chr19:33551563 T/G cg27124370 chr19:33622961 WDR88 0.47 7.13 0.36 5.83e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.6 0.46 1.76e-19 Bipolar disorder; LIHC cis rs9549328 0.731 rs55804996 chr13:113625367 A/G cg18289306 chr13:113640169 MCF2L 0.42 6.49 0.33 3.02e-10 Systolic blood pressure; LIHC cis rs7224737 1.000 rs1869365 chr17:40293865 T/C cg02228675 chr17:40259724 DHX58 -0.25 -5.8 -0.3 1.5e-8 Fibrinogen levels; LIHC cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.627 rs860891 chr16:4586529 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.43 -6.29 -0.32 9.72e-10 Schizophrenia; LIHC cis rs2439831 0.850 rs2228368 chr15:44102010 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.52 0.42 5.17e-16 Lung cancer in ever smokers; LIHC cis rs238295 0.805 rs1983694 chr20:5574134 T/C cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -7.02 -0.35 1.22e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs2257205 0.600 rs8071081 chr17:56709055 T/G cg05425664 chr17:57184151 TRIM37 -0.59 -6.5 -0.33 2.86e-10 Pancreatic cancer; LIHC cis rs62402013 1 rs62402013 chr6:26915000 A/G cg18867708 chr6:26865862 GUSBL1 0.54 8.16 0.4 6.42e-15 Schizophrenia; LIHC cis rs3768617 0.510 rs7529465 chr1:183096880 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs600806 0.778 rs10857787 chr1:110010289 C/T cg02415029 chr1:110025642 ATXN7L2 -0.51 -6.8 -0.35 4.66e-11 Intelligence (multi-trait analysis); LIHC cis rs17685 0.753 rs1637039 chr7:75693009 C/T cg04592579 chr7:75616294 TMEM120A 0.4 7.0 0.35 1.32e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2120019 0.938 rs2289582 chr15:75310394 T/C cg11632617 chr15:75315747 PPCDC -0.48 -6.79 -0.34 4.94e-11 Blood trace element (Zn levels); LIHC trans rs2243480 0.908 rs1532573 chr7:65798802 A/G cg10756647 chr7:56101905 PSPH -1.03 -12.6 -0.56 3.61e-30 Diabetic kidney disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07097722 chr20:43247325 PKIG 0.38 6.29 0.32 9.87e-10 Longevity; LIHC cis rs2404602 0.692 rs7174673 chr15:77071998 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.81e-9 Blood metabolite levels; LIHC cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.42 0.45 6.79e-19 Platelet count; LIHC cis rs7106204 0.668 rs7119362 chr11:24218132 G/T ch.11.24196551F chr11:24239977 NA 0.77 10.52 0.49 1.35e-22 Response to Homoharringtonine (cytotoxicity); LIHC cis rs360798 0.532 rs12994674 chr2:62996645 G/A cg17519650 chr2:63277830 OTX1 -0.53 -7.92 -0.39 3.33e-14 Coronary artery disease; LIHC cis rs13108904 0.557 rs1680041 chr4:1238521 C/T cg20887711 chr4:1340912 KIAA1530 -0.71 -10.72 -0.5 2.64e-23 Obesity-related traits; LIHC cis rs10540 0.730 rs34690033 chr11:492677 G/C cg03576123 chr11:487126 PTDSS2 -1.08 -8.06 -0.4 1.26e-14 Body mass index; LIHC cis rs1008375 0.900 rs4698622 chr4:17589557 C/T cg16339924 chr4:17578868 LAP3 0.56 7.48 0.38 6.18e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9811920 0.609 rs17174947 chr3:99598884 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs11690935 0.788 rs10201053 chr2:172889558 A/G cg13550731 chr2:172543902 DYNC1I2 -0.49 -7.74 -0.39 1.16e-13 Schizophrenia; LIHC cis rs796364 0.806 rs79897806 chr2:201073968 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.78 -8.35 -0.41 1.73e-15 Schizophrenia; LIHC cis rs561341 1.000 rs2344312 chr17:30243583 G/T cg12193833 chr17:30244370 NA -0.53 -6.1 -0.31 2.94e-9 Hip circumference adjusted for BMI; LIHC cis rs4589502 1.000 rs75502100 chr15:67131417 T/C cg09911534 chr15:67153556 NA -0.49 -5.98 -0.31 5.72e-9 Lung cancer (smoking interaction); LIHC cis rs2292096 1.000 rs34596352 chr1:200785330 C/T cg11814564 chr1:200748674 CAMSAP1L1 -0.45 -5.87 -0.3 1.02e-8 Epilepsy; LIHC cis rs68170813 0.523 rs12532447 chr7:106940476 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08052428 chr9:135996421 RALGDS 0.47 7.44 0.37 8.16e-13 Pancreatic cancer; LIHC cis rs2204008 0.701 rs3898237 chr12:38219714 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.75 0.5 2.1e-23 Bladder cancer; LIHC cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg20887711 chr4:1340912 KIAA1530 0.64 9.82 0.47 3.19e-20 Longevity; LIHC cis rs9457247 0.566 rs10946207 chr6:167456036 C/T cg07741184 chr6:167504864 NA 0.35 7.86 0.39 5.17e-14 Crohn's disease; LIHC cis rs7945705 0.934 rs1988709 chr11:8882890 A/T cg12365402 chr11:9010492 NRIP3 0.29 7.4 0.37 1.07e-12 Hemoglobin concentration; LIHC cis rs1801251 0.963 rs6739638 chr2:233576015 G/A cg25237894 chr2:233734115 C2orf82 0.57 11.02 0.51 2.3e-24 Coronary artery disease; LIHC cis rs17152411 0.652 rs7070792 chr10:126611155 G/A cg07906193 chr10:126599966 NA -0.29 -5.74 -0.3 2.05e-8 Height; LIHC cis rs2439831 0.867 rs2255042 chr15:43834318 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.54 -7.37 -0.37 1.27e-12 Lung cancer in ever smokers; LIHC cis rs7131987 0.650 rs10843384 chr12:29472409 C/T cg12903224 chr12:29470962 FAR2 -0.41 -6.66 -0.34 1.12e-10 QT interval; LIHC cis rs8141529 0.636 rs5762799 chr22:29187380 G/T cg15103426 chr22:29168792 CCDC117 0.5 7.45 0.37 7.79e-13 Lymphocyte counts; LIHC cis rs9911578 1.000 rs9911578 chr17:56953147 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs12144094 0.832 rs6683122 chr1:120242179 G/T cg20995928 chr1:120229863 NA 0.42 7.13 0.36 5.88e-12 Height; LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg08358671 chr1:185286807 IVNS1ABP -0.6 -6.69 -0.34 9.08e-11 Bronchial neuroendocrine tumor; LIHC cis rs7772486 0.774 rs6930181 chr6:146180974 A/T cg23711669 chr6:146136114 FBXO30 -0.52 -9.53 -0.46 3.11e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs2204008 0.745 rs8189516 chr12:38239084 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC cis rs4800452 0.956 rs4308051 chr18:20735461 T/G cg26136497 chr18:20735537 CABLES1 -0.44 -5.84 -0.3 1.22e-8 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs12079745 0.793 rs12076519 chr1:169283540 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -6.91 -0.35 2.36e-11 QT interval; LIHC cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.04 -0.58 8.18e-32 Vitiligo; LIHC cis rs7520050 0.581 rs3855959 chr1:46633874 C/T cg15696662 chr1:46669221 C1orf190;POMGNT1 0.42 6.4 0.33 5e-10 Red blood cell count;Reticulocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25365794 chr17:8022404 ALOXE3 0.52 7.27 0.37 2.47e-12 Pancreatic cancer; LIHC cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg14078730 chr11:63896557 MACROD1 0.33 6.11 0.31 2.75e-9 Platelet count; LIHC cis rs4689592 0.554 rs66925245 chr4:7071999 C/T cg19539972 chr4:7069911 GRPEL1 -0.73 -9.94 -0.47 1.24e-20 Monocyte percentage of white cells; LIHC cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg03517284 chr6:25882590 NA 0.89 12.0 0.54 6.2e-28 Blood metabolite levels; LIHC cis rs17106184 0.892 rs3789581 chr1:51019450 T/C cg07174182 chr1:51127561 FAF1 -0.66 -7.07 -0.36 8.68e-12 Type 2 diabetes; LIHC cis rs2842992 0.750 rs2758354 chr6:160125854 A/G cg11366901 chr6:160182831 ACAT2 0.97 16.16 0.66 4.83e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs4853012 0.838 rs4563249 chr2:74354016 G/T cg01017244 chr2:74357527 NA 0.65 12.08 0.55 3.09e-28 Gestational age at birth (maternal effect); LIHC cis rs7647973 0.710 rs12637313 chr3:49645458 A/G cg03060546 chr3:49711283 APEH 0.61 6.88 0.35 2.89e-11 Menarche (age at onset); LIHC cis rs12744310 0.943 rs35502198 chr1:41768541 T/G cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg20607798 chr8:58055168 NA 0.6 7.32 0.37 1.82e-12 Developmental language disorder (linguistic errors); LIHC cis rs7572733 0.534 rs700672 chr2:198691455 G/A cg03934865 chr2:198174659 NA 0.45 6.53 0.33 2.35e-10 Dermatomyositis; LIHC trans rs7618501 0.602 rs2071206 chr3:50160109 G/A cg21659725 chr3:3221576 CRBN -0.68 -10.86 -0.51 8.3e-24 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg11764359 chr7:65958608 NA 0.6 6.38 0.33 5.71e-10 Diabetic kidney disease; LIHC cis rs7959452 0.684 rs11177615 chr12:69754189 G/A cg14784868 chr12:69753453 YEATS4 0.96 20.74 0.75 1.88e-62 Blood protein levels; LIHC cis rs7131987 0.621 rs3782506 chr12:29445422 A/C cg00204748 chr12:29376779 FAR2 -0.4 -7.31 -0.37 1.87e-12 QT interval; LIHC trans rs1814175 0.647 rs4881649 chr11:49845560 A/G cg15704280 chr7:45808275 SEPT13 -0.7 -12.09 -0.55 2.99e-28 Height; LIHC cis rs4665809 1.000 rs12471809 chr2:26307140 A/G cg27170947 chr2:26402098 FAM59B -0.62 -7.71 -0.38 1.37e-13 Gut microbiome composition (summer); LIHC cis rs929354 0.742 rs10251112 chr7:156963524 A/G cg17757837 chr7:157058334 UBE3C 0.72 11.74 0.54 5.62e-27 Body mass index; LIHC trans rs6733379 0.588 rs2193790 chr2:34445953 A/G cg13872831 chr3:50377988 RASSF1 0.26 6.5 0.33 2.91e-10 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs9970334 0.596 rs709209 chr1:6278414 A/G cg15892785 chr1:6309343 GPR153 -0.45 -6.26 -0.32 1.12e-9 Resting heart rate; LIHC cis rs7520050 0.966 rs785464 chr1:46523089 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.93 0.31 7.49e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1065656 0.571 rs12149777 chr16:1834724 A/G cg09540102 chr16:1822124 NME3;MRPS34;EME2 -0.41 -7.24 -0.36 2.95e-12 Insulin-like growth factors; LIHC cis rs9389248 0.500 rs116273677 chr6:135339135 A/C cg24558204 chr6:135376177 HBS1L 0.41 6.68 0.34 9.85e-11 High light scatter reticulocyte percentage of red cells; LIHC cis rs8180040 0.764 rs11712716 chr3:47193432 T/C cg27129171 chr3:47204927 SETD2 0.69 12.1 0.55 2.64e-28 Colorectal cancer; LIHC cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.22 0.32 1.43e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs748404 0.660 rs690446 chr15:43761264 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.88 0.39 4.43e-14 Lung cancer; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 21.57 0.76 9.39e-66 Prudent dietary pattern; LIHC cis rs798554 0.759 rs2644309 chr7:2889034 T/C cg13628971 chr7:2884303 GNA12 0.6 10.08 0.48 4.41e-21 Height; LIHC cis rs4891159 0.548 rs617823 chr18:74120233 A/G cg24786174 chr18:74118243 ZNF516 0.86 18.09 0.7 8.49e-52 Longevity; LIHC cis rs2304069 0.507 rs13167061 chr5:149388624 T/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.6 8.49 0.42 6.46e-16 HIV-1 control; LIHC cis rs55665837 1.000 rs11023223 chr11:14457112 A/G cg19336497 chr11:14380999 RRAS2 -0.44 -8.12 -0.4 8.51e-15 Vitamin D levels; LIHC cis rs11690935 0.959 rs6758704 chr2:172655097 T/C cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.54 -0.69 1.36e-49 Schizophrenia; LIHC cis rs6748734 0.817 rs4465762 chr2:241798862 G/A cg08694578 chr2:241835147 C2orf54 -0.51 -8.02 -0.4 1.67e-14 Urinary metabolites; LIHC cis rs9303401 0.614 rs34550282 chr17:57092788 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.81 0.54 3.03e-27 Cognitive test performance; LIHC trans rs9858542 0.953 rs11710037 chr3:49675334 C/G cg21659725 chr3:3221576 CRBN -0.59 -6.61 -0.34 1.5e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6120849 0.754 rs3746435 chr20:33587198 G/C cg06115741 chr20:33292138 TP53INP2 0.5 5.72 0.3 2.34e-8 Protein C levels; LIHC cis rs6754311 0.731 rs3769005 chr2:136603366 C/G cg07169764 chr2:136633963 MCM6 -0.65 -9.8 -0.47 3.72e-20 Mosquito bite size; LIHC cis rs3845702 0.668 rs12693215 chr2:180826007 A/C cg01881094 chr2:180872142 CWC22 -1.13 -10.41 -0.49 3.17e-22 Schizophrenia; LIHC cis rs6545883 0.894 rs9677047 chr2:61585295 C/G cg15711740 chr2:61764176 XPO1 0.42 5.76 0.3 1.92e-8 Tuberculosis; LIHC trans rs13309098 0.793 rs17092951 chr7:48789477 A/T cg01806741 chr6:1527072 NA 0.55 6.1 0.31 2.86e-9 QT interval (ambient particulate matter interaction); LIHC cis rs11030122 0.702 rs10835403 chr11:3990941 A/C cg18678763 chr11:4115507 RRM1 0.47 6.5 0.33 2.81e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg05564831 chr3:52568323 NT5DC2 0.38 6.15 0.32 2.19e-9 Bipolar disorder; LIHC cis rs9326248 1.000 rs3736120 chr11:117032125 G/T cg11861562 chr11:117069780 TAGLN 0.5 8.2 0.41 5.05e-15 Blood protein levels; LIHC cis rs600806 0.778 rs4970766 chr1:110013955 A/G cg08911820 chr1:110026001 ATXN7L2 0.58 7.33 0.37 1.71e-12 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.647 rs4886840 chr15:77179002 A/G cg03037974 chr15:76606532 NA -0.6 -10.29 -0.49 8.21e-22 Blood metabolite levels; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg11905131 chr22:24372483 LOC391322 -0.73 -11.22 -0.52 4.2e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs60871478 1.000 rs34761279 chr7:794471 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.55 6.44 0.33 3.94e-10 Cerebrospinal P-tau181p levels; LIHC cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg13397359 chr6:42928475 GNMT 0.75 10.46 0.49 2.08e-22 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs12477438 0.520 rs6756650 chr2:99801800 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.21 0.61 2.47e-36 Chronic sinus infection; LIHC cis rs2576037 0.526 rs2571026 chr18:44561795 C/T cg19077165 chr18:44547161 KATNAL2 0.43 6.49 0.33 3.09e-10 Personality dimensions; LIHC cis rs72720396 0.789 rs10922910 chr1:91199862 G/T cg13456504 chr1:91191583 NA 0.51 7.33 0.37 1.67e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs477692 1.000 rs516704 chr10:131419879 G/A cg05714579 chr10:131428358 MGMT 0.44 7.31 0.37 1.85e-12 Response to temozolomide; LIHC trans rs11098499 0.754 rs10212714 chr4:120254302 T/C cg25214090 chr10:38739885 LOC399744 0.52 8.44 0.42 9.17e-16 Corneal astigmatism; LIHC cis rs2153535 0.935 rs11243254 chr6:8381242 C/T cg07606381 chr6:8435919 SLC35B3 -0.42 -6.01 -0.31 4.75e-9 Motion sickness; LIHC cis rs67478160 0.584 rs2295147 chr14:104195664 A/G cg08213375 chr14:104286397 PPP1R13B -0.49 -9.42 -0.45 7.07e-19 Schizophrenia; LIHC cis rs6456156 1.000 rs9457274 chr6:167520865 G/T cg07741184 chr6:167504864 NA 0.25 6.15 0.32 2.11e-9 Primary biliary cholangitis; LIHC cis rs2274273 0.870 rs3783652 chr14:55854208 A/G cg01864836 chr14:55583639 NA -0.38 -6.66 -0.34 1.08e-10 Protein biomarker; LIHC cis rs17685 0.523 rs10246583 chr7:75746667 C/A cg04610667 chr7:75704037 NA -0.33 -6.0 -0.31 5.08e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg12463550 chr7:65579703 CRCP -0.66 -6.85 -0.35 3.41e-11 Diabetic kidney disease; LIHC cis rs9457247 0.765 rs9295385 chr6:167448181 A/G cg07741184 chr6:167504864 NA 0.31 6.42 0.33 4.56e-10 Crohn's disease; LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg13126279 chr21:47581558 C21orf56 -0.38 -5.91 -0.3 8.16e-9 Testicular germ cell tumor; LIHC cis rs11969893 0.737 rs4098482 chr6:101377808 C/T cg12253828 chr6:101329408 ASCC3 1.04 13.07 0.58 5.89e-32 Economic and political preferences (immigration/crime); LIHC cis rs10771431 0.597 rs3759274 chr12:9353875 T/C cg08997352 chr12:9597637 DDX12 -0.49 -7.61 -0.38 2.62e-13 Breast size; LIHC cis rs7131987 0.874 rs10843366 chr12:29407903 T/C cg05697976 chr12:29376483 FAR2 0.31 6.38 0.33 5.76e-10 QT interval; LIHC cis rs910316 0.935 rs11159119 chr14:75636967 C/T cg08847533 chr14:75593920 NEK9 -0.87 -18.99 -0.72 2.08e-55 Height; LIHC cis rs782590 0.967 rs11125581 chr2:55796527 C/G cg03859395 chr2:55845619 SMEK2 0.93 16.34 0.66 9.46e-45 Metabolic syndrome; LIHC cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.94 0.31 7.02e-9 Electroencephalogram traits; LIHC cis rs62034325 0.697 rs710410 chr16:28603342 A/G cg07382826 chr16:28625726 SULT1A1 0.52 7.84 0.39 5.68e-14 Body mass index; LIHC cis rs1882538 0.512 rs13241734 chr7:133122742 C/G cg10665199 chr7:133106180 EXOC4 0.53 8.51 0.42 5.39e-16 Intelligence (multi-trait analysis); LIHC cis rs2906856 0.921 rs1019076 chr12:68398118 C/T cg15249341 chr12:68405565 NA 0.34 7.06 0.36 9.47e-12 Mosquito bite size; LIHC cis rs10416265 0.528 rs10420258 chr19:33602757 C/T cg27124370 chr19:33622961 WDR88 0.49 6.86 0.35 3.18e-11 Bone properties (heel); LIHC cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg06481639 chr22:41940642 POLR3H -0.69 -7.23 -0.36 3.26e-12 Vitiligo; LIHC cis rs7412746 0.658 rs72704652 chr1:150819470 A/G cg15448220 chr1:150897856 SETDB1 0.39 5.85 0.3 1.17e-8 Melanoma; LIHC cis rs1559088 0.501 rs35492529 chr19:33597495 C/G cg17764715 chr19:33622953 WDR88 0.49 6.41 0.33 4.71e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7534824 0.625 rs61782084 chr1:101515298 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.76 7.15 0.36 5.43e-12 Refractive astigmatism; LIHC cis rs778371 0.834 rs778364 chr2:233777859 A/G cg08000102 chr2:233561755 GIGYF2 0.77 8.4 0.41 1.22e-15 Schizophrenia; LIHC trans rs1005277 0.579 rs1740732 chr10:38491385 C/T cg04469686 chr1:162760199 HSD17B7 -0.39 -6.06 -0.31 3.68e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8114671 0.904 rs6060197 chr20:33654315 C/T cg07148914 chr20:33460835 GGT7 -0.55 -8.29 -0.41 2.63e-15 Height; LIHC cis rs6582630 0.519 rs11519914 chr12:38287014 A/G cg26384229 chr12:38710491 ALG10B 0.58 8.08 0.4 1.1e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs4638749 0.677 rs2219082 chr2:108854182 C/A cg25838818 chr2:108905173 SULT1C2 -0.41 -7.26 -0.37 2.71e-12 Blood pressure; LIHC cis rs1401999 0.650 rs3792585 chr3:183646222 A/G cg05044414 chr3:183734942 ABCC5 0.31 5.82 0.3 1.37e-8 Anterior chamber depth; LIHC cis rs1215050 0.818 rs6532703 chr4:98777486 A/T cg05340658 chr4:99064831 C4orf37 0.45 6.19 0.32 1.73e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs709400 0.633 rs3783395 chr14:103895020 T/C cg26031613 chr14:104095156 KLC1 0.74 10.03 0.48 6.13e-21 Body mass index; LIHC cis rs240764 0.782 rs369125 chr6:101118400 G/A cg09795085 chr6:101329169 ASCC3 0.53 7.29 0.37 2.15e-12 Neuroticism; LIHC cis rs11098499 0.774 rs11098505 chr4:120284627 C/T cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs3820068 0.581 rs2861387 chr1:15951296 G/A cg17385448 chr1:15911702 AGMAT 0.34 6.03 0.31 4.2e-9 Systolic blood pressure; LIHC cis rs797680 0.856 rs10874759 chr1:93630172 G/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.67e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC trans rs875971 1.000 rs778699 chr7:65868290 G/A cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs7799006 0.723 rs12673108 chr7:2286487 C/A cg02951883 chr7:2050386 MAD1L1 -0.4 -6.11 -0.31 2.7e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9858542 0.953 rs9858280 chr3:49597737 T/C cg03060546 chr3:49711283 APEH -0.47 -6.33 -0.32 7.56e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2806561 0.734 rs667211 chr1:23516142 T/C cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.45e-11 Height; LIHC cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg20295408 chr7:1910781 MAD1L1 -0.4 -5.77 -0.3 1.78e-8 Bipolar disorder and schizophrenia; LIHC cis rs1577917 0.876 rs1582126 chr6:86697205 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -9.56 -0.46 2.35e-19 Response to antipsychotic treatment; LIHC cis rs9486719 0.948 rs2472881 chr6:96862562 C/T cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs6840360 0.967 rs10028410 chr4:152606573 T/C cg22705602 chr4:152727874 NA -0.31 -6.47 -0.33 3.41e-10 Intelligence (multi-trait analysis); LIHC cis rs17376456 0.877 rs67066109 chr5:93494101 G/C cg25358565 chr5:93447407 FAM172A 1.1 10.02 0.48 6.65e-21 Diabetic retinopathy; LIHC trans rs7246657 0.941 rs7259618 chr19:37750719 G/A cg10208301 chr11:6592745 DNHD1 0.47 6.25 0.32 1.21e-9 Coronary artery calcification; LIHC cis rs17376456 0.825 rs17372725 chr5:93135588 C/A cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC trans rs10506458 0.915 rs12426017 chr12:63396272 T/G cg22491629 chr6:157744540 C6orf35 -0.6 -10.89 -0.51 6.68e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs4665809 1.000 rs6709595 chr2:26259885 A/G cg27170947 chr2:26402098 FAM59B -0.65 -8.17 -0.4 6.17e-15 Gut microbiome composition (summer); LIHC cis rs507080 0.922 rs519982 chr11:118565231 C/T cg04173919 chr11:118528438 PHLDB1 0.36 6.6 0.34 1.53e-10 Serum metabolite levels; LIHC cis rs651907 0.535 rs12631513 chr3:101517476 A/C cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs1371867 0.513 rs1542812 chr8:101207064 G/A cg06002616 chr8:101225028 SPAG1 0.4 6.71 0.34 7.92e-11 Atrioventricular conduction; LIHC cis rs8072100 0.764 rs2644349 chr17:45641743 G/A cg08085267 chr17:45401833 C17orf57 0.39 5.85 0.3 1.15e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs61931739 0.500 rs7489130 chr12:34539674 C/A cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg09455208 chr3:40491958 NA -0.39 -7.78 -0.39 8.67e-14 Renal cell carcinoma; LIHC cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg03806693 chr22:41940476 POLR3H -1.07 -12.47 -0.56 1.15e-29 Vitiligo; LIHC cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs2645694 0.651 rs2703144 chr4:77830505 C/G cg03477792 chr4:77819574 ANKRD56 0.56 7.52 0.38 4.81e-13 Emphysema distribution in smoking; LIHC cis rs6782228 0.606 rs10048945 chr3:128409680 C/T cg16766828 chr3:128327626 NA -0.4 -6.39 -0.33 5.36e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC trans rs13381277 1.000 rs9952875 chr18:74327943 G/C cg17352830 chr21:37617589 DOPEY2 -0.55 -6.41 -0.33 4.77e-10 Dental caries; LIHC trans rs7618501 1.000 rs7431106 chr3:49808374 G/A cg21582582 chr3:182698605 DCUN1D1 0.52 6.87 0.35 3.02e-11 Intelligence (multi-trait analysis); LIHC trans rs950169 0.690 rs12901166 chr15:84699113 G/A cg24036039 chr1:3397125 ARHGEF16 0.39 6.21 0.32 1.57e-9 Schizophrenia; LIHC cis rs4908768 0.906 rs12568293 chr1:8540912 C/T cg20416874 chr1:8611966 RERE -0.56 -9.0 -0.44 1.56e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2832191 0.720 rs7277028 chr21:30494604 T/C cg24692254 chr21:30365293 RNF160 -0.6 -10.48 -0.49 1.77e-22 Dental caries; LIHC cis rs2404602 0.692 rs12911902 chr15:77053575 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.7e-9 Blood metabolite levels; LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.93 0.57 2.1e-31 Prudent dietary pattern; LIHC cis rs344364 0.602 rs2437744 chr16:1908451 C/T cg00564555 chr16:1970112 NA 0.26 6.08 0.31 3.28e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs2204008 0.692 rs11613378 chr12:38213138 T/A cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs1865721 1.000 rs62089507 chr18:73179019 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.67 -0.38 1.77e-13 Intelligence; LIHC cis rs748404 0.697 rs498227 chr15:43573052 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.51 8.68 0.42 1.61e-16 Lung cancer; LIHC cis rs400736 0.729 rs9434948 chr1:8004963 A/C cg25007680 chr1:8021821 PARK7 -0.46 -7.29 -0.37 2.13e-12 Response to antidepressants and depression; LIHC cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg12016809 chr21:47604291 C21orf56 0.42 6.21 0.32 1.5e-9 Testicular germ cell tumor; LIHC cis rs2732480 0.538 rs1387259 chr12:48703522 C/T cg21466736 chr12:48725269 NA 0.71 10.78 0.5 1.62e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs6912958 0.712 rs4498321 chr6:88339251 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.98 -0.4 2.21e-14 Monocyte percentage of white cells; LIHC cis rs9303401 0.659 rs62083368 chr17:56878062 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.32 0.58 6.47e-33 Cognitive test performance; LIHC cis rs7395581 0.918 rs10838692 chr11:47345100 T/C cg25783544 chr11:47291846 MADD 0.41 5.95 0.31 6.8e-9 HDL cholesterol; LIHC cis rs6466055 0.720 rs2030776 chr7:105008458 C/G cg04380332 chr7:105027541 SRPK2 -0.37 -6.96 -0.35 1.8e-11 Schizophrenia; LIHC cis rs514406 0.679 rs541852 chr1:53256834 A/G cg24675658 chr1:53192096 ZYG11B 0.83 13.75 0.6 1.53e-34 Monocyte count; LIHC trans rs2243480 1.000 rs316326 chr7:65609453 T/C cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC trans rs7613875 0.600 rs2247510 chr3:50126215 A/C cg21659725 chr3:3221576 CRBN 0.54 8.04 0.4 1.48e-14 Body mass index; LIHC cis rs7666738 0.546 rs2098935 chr4:98914376 A/G cg05340658 chr4:99064831 C4orf37 0.49 6.51 0.33 2.66e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg00800038 chr16:89945340 TCF25 -0.66 -10.56 -0.5 9.4e-23 Skin colour saturation; LIHC cis rs9467160 0.520 rs2753910 chr6:24442473 C/T cg20631270 chr6:24437470 GPLD1 -0.5 -7.62 -0.38 2.56e-13 Liver enzyme levels; LIHC cis rs7534824 0.625 rs12563134 chr1:101468558 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.71 -7.54 -0.38 4.22e-13 Refractive astigmatism; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg03862414 chr17:40824241 PLEKHH3 0.36 6.07 0.31 3.41e-9 Alopecia areata; LIHC trans rs10411161 0.702 rs11878580 chr19:52388485 C/T cg22319618 chr22:45562946 NUP50 -0.62 -8.49 -0.42 6.32e-16 Breast cancer; LIHC cis rs9682041 0.696 rs6786542 chr3:170105378 C/T cg11886554 chr3:170076028 SKIL 0.63 5.84 0.3 1.23e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs765787 0.530 rs3759895 chr15:45543870 G/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.51e-13 Uric acid levels; LIHC cis rs28830936 1.000 rs4924575 chr15:42096926 C/T cg17847044 chr15:42102381 MAPKBP1 -0.33 -6.68 -0.34 9.73e-11 Diastolic blood pressure; LIHC cis rs8103278 0.507 rs7246377 chr19:46292259 G/A cg02376097 chr19:46275166 DMPK 0.51 8.73 0.43 1.12e-16 Coronary artery disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08635118 chr7:6144369 USP42 -0.48 -6.16 -0.32 1.99e-9 Systolic blood pressure; LIHC cis rs1941023 0.503 rs894591 chr11:60132647 T/C cg08716584 chr11:60157161 MS4A7 -0.35 -8.13 -0.4 8e-15 Congenital heart disease (maternal effect); LIHC cis rs9914578 0.943 rs7225843 chr17:2001825 A/G cg16513277 chr17:2031491 SMG6 -0.56 -7.59 -0.38 3.03e-13 Body mass index; LIHC cis rs4665809 1.000 rs2384323 chr2:26306473 C/T cg27170947 chr2:26402098 FAM59B -0.63 -7.98 -0.4 2.18e-14 Gut microbiome composition (summer); LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg21003380 chr1:156261207 TMEM79 0.38 6.07 0.31 3.49e-9 Tonsillectomy; LIHC cis rs7772486 0.754 rs6570708 chr6:145989428 C/T cg13319975 chr6:146136371 FBXO30 0.42 6.95 0.35 1.86e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4148883 0.689 rs1311621 chr4:100014018 T/C cg12011299 chr4:100065546 ADH4 0.35 7.15 0.36 5.14e-12 Alcohol dependence; LIHC cis rs17253792 0.822 rs28478195 chr14:56047851 G/A cg01858014 chr14:56050164 KTN1 -0.74 -8.03 -0.4 1.61e-14 Putamen volume; LIHC cis rs3096299 0.591 rs748940 chr16:89440757 T/A cg08392591 chr16:89556376 ANKRD11 0.41 6.16 0.32 2e-9 Multiple myeloma (IgH translocation); LIHC cis rs7208859 0.524 rs8065744 chr17:29099449 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.18 0.4 5.73e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs477692 0.569 rs10764884 chr10:131308370 G/C cg05714579 chr10:131428358 MGMT 0.4 6.47 0.33 3.47e-10 Response to temozolomide; LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg18279126 chr7:2041391 MAD1L1 0.38 6.24 0.32 1.31e-9 Bipolar disorder and schizophrenia; LIHC cis rs1789 0.903 rs4453929 chr4:15672173 T/G cg21329975 chr4:15471214 CC2D2A -0.4 -5.99 -0.31 5.2e-9 Blood protein levels; LIHC cis rs35110281 0.659 rs11909064 chr21:45092095 G/C cg04455712 chr21:45112962 RRP1B 0.51 8.68 0.43 1.59e-16 Mean corpuscular volume; LIHC cis rs870825 0.860 rs72689284 chr4:185596680 A/G cg04058563 chr4:185651563 MLF1IP 0.84 7.01 0.35 1.31e-11 Blood protein levels; LIHC cis rs892961 1.000 rs1075457 chr17:75400737 A/G cg01320579 chr17:75405842 SEPT9 -0.44 -6.42 -0.33 4.43e-10 Airflow obstruction; LIHC cis rs858239 0.601 rs10263110 chr7:23160551 G/A cg23682824 chr7:23144976 KLHL7 0.42 6.37 0.33 5.99e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs7937890 1.000 rs2970335 chr11:14325401 A/C cg23387056 chr11:14280742 SPON1 -0.42 -5.84 -0.3 1.21e-8 Mitochondrial DNA levels; LIHC cis rs4819052 0.851 rs4819049 chr21:46673086 C/G cg11663144 chr21:46675770 NA -0.31 -5.83 -0.3 1.26e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11098499 0.954 rs13151285 chr4:120314741 C/A cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs79387448 0.745 rs17027428 chr2:103163175 G/A cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs10751667 0.643 rs10794350 chr11:946070 A/G cg06064525 chr11:970664 AP2A2 -0.54 -14.57 -0.62 9.94e-38 Alzheimer's disease (late onset); LIHC cis rs17102423 0.530 rs4902357 chr14:65542067 C/G cg16583315 chr14:65563665 MAX -0.39 -7.88 -0.39 4.33e-14 Obesity-related traits; LIHC cis rs7772486 0.754 rs702304 chr6:145990797 A/G cg23711669 chr6:146136114 FBXO30 -0.76 -14.02 -0.6 1.36e-35 Lobe attachment (rater-scored or self-reported); LIHC cis rs155076 1.000 rs195570 chr13:21867580 T/G cg11317459 chr13:21872234 NA -1.21 -12.9 -0.57 2.75e-31 White matter hyperintensity burden; LIHC cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg16405210 chr4:1374714 KIAA1530 0.7 10.43 0.49 2.7e-22 Obesity-related traits; LIHC cis rs1008375 1.000 rs10440301 chr4:17663199 G/A cg02297831 chr4:17616191 MED28 0.41 5.73 0.3 2.24e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6912958 0.754 rs6918909 chr6:88247251 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.07 -0.4 1.19e-14 Monocyte percentage of white cells; LIHC cis rs2153535 0.580 rs6921964 chr6:8446395 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.99 0.4 2.09e-14 Motion sickness; LIHC cis rs12477438 0.520 rs11123761 chr2:99705903 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.19 21.13 0.75 5.53e-64 Chronic sinus infection; LIHC cis rs8017423 0.967 rs7151776 chr14:90724803 A/G cg04374321 chr14:90722782 PSMC1 0.75 14.43 0.62 3.24e-37 Mortality in heart failure; LIHC cis rs7412746 0.611 rs4970984 chr1:150887377 T/C cg15448220 chr1:150897856 SETDB1 0.39 6.21 0.32 1.52e-9 Melanoma; LIHC cis rs2412488 0.893 rs6822201 chr4:54359743 T/C cg22241045 chr4:54363911 LNX1 0.47 7.65 0.38 2e-13 DNA methylation (variation); LIHC cis rs798766 1.000 rs11732213 chr4:1704244 T/C cg15202627 chr4:1685555 FAM53A -0.5 -5.79 -0.3 1.58e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs1577917 0.655 rs9444354 chr6:86291935 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.18 0.32 1.77e-9 Response to antipsychotic treatment; LIHC cis rs56235845 0.694 rs9313758 chr5:176773091 T/G cg17509989 chr5:176798049 RGS14 0.6 7.84 0.39 5.68e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg08219700 chr8:58056026 NA 0.51 6.24 0.32 1.29e-9 Developmental language disorder (linguistic errors); LIHC cis rs875971 1.000 rs4718357 chr7:65960878 A/G cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.54e-9 Aortic root size; LIHC cis rs2071303 0.836 rs198835 chr6:26113994 T/G cg18357526 chr6:26021779 HIST1H4A -0.54 -7.98 -0.4 2.21e-14 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.554 rs6800204 chr3:9995404 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -7.96 -0.4 2.63e-14 Alzheimer's disease; LIHC cis rs2832191 0.903 rs11700687 chr21:30486767 A/G cg24692254 chr21:30365293 RNF160 -0.64 -11.38 -0.52 1.19e-25 Dental caries; LIHC cis rs17685 0.753 rs2108274 chr7:75781636 C/A cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2404602 0.735 rs11638767 chr15:76655938 T/C cg23625390 chr15:77176239 SCAPER -0.48 -8.0 -0.4 2.01e-14 Blood metabolite levels; LIHC cis rs644799 0.544 rs555556 chr11:95618425 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.57 8.13 0.4 8.17e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs13401104 0.796 rs1466204 chr2:237121154 C/A cg19324714 chr2:237145437 ASB18 0.37 5.85 0.3 1.13e-8 Educational attainment; LIHC cis rs6546550 0.869 rs6720498 chr2:70124805 T/C cg02498382 chr2:70120550 SNRNP27 -0.43 -7.1 -0.36 7.05e-12 Prevalent atrial fibrillation; LIHC cis rs589448 0.867 rs623853 chr12:69753830 G/A cg14784868 chr12:69753453 YEATS4 0.99 23.08 0.78 1.05e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs826838 0.834 rs2387842 chr12:38736442 T/C cg26384229 chr12:38710491 ALG10B 1.05 14.67 0.62 3.99e-38 Heart rate; LIHC cis rs477692 0.905 rs544217 chr10:131420584 A/G cg19680672 chr10:131412579 MGMT -0.43 -6.64 -0.34 1.21e-10 Response to temozolomide; LIHC cis rs9549328 0.800 rs9549620 chr13:113633421 T/A cg00071026 chr13:113650936 MCF2L -0.37 -5.86 -0.3 1.11e-8 Systolic blood pressure; LIHC cis rs10876993 0.893 rs4760168 chr12:58087737 T/G cg15848620 chr12:58087721 OS9 -0.58 -7.66 -0.38 1.93e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs11098499 0.954 rs11729521 chr4:120416788 T/C cg09307838 chr4:120376055 NA 0.77 12.25 0.55 7.23e-29 Corneal astigmatism; LIHC cis rs11711311 1.000 rs9811746 chr3:113515060 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.94 -0.35 1.92e-11 IgG glycosylation; LIHC cis rs854765 0.603 rs4506967 chr17:17990474 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.34 6.3 0.32 9.34e-10 Total body bone mineral density; LIHC cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg14393609 chr7:65229607 NA -0.44 -6.57 -0.33 1.83e-10 Aortic root size; LIHC cis rs2607426 0.681 rs2607411 chr19:41268555 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.54 -6.39 -0.33 5.5e-10 Blood protein levels; LIHC cis rs2239547 0.522 rs2581801 chr3:52972907 G/T cg11645453 chr3:52864694 ITIH4 -0.23 -5.78 -0.3 1.65e-8 Schizophrenia; LIHC cis rs35110281 0.591 rs162369 chr21:44931965 G/A cg21573476 chr21:45109991 RRP1B -0.48 -8.79 -0.43 7.41e-17 Mean corpuscular volume; LIHC cis rs250677 0.958 rs36068 chr5:148417512 C/T cg18129178 chr5:148520854 ABLIM3 -0.48 -6.49 -0.33 3.1e-10 Breast cancer; LIHC trans rs62103177 0.525 rs9949598 chr18:77753037 G/A cg05926928 chr17:57297772 GDPD1 -0.58 -6.63 -0.34 1.32e-10 Opioid sensitivity; LIHC cis rs7208859 0.623 rs12103440 chr17:29086657 A/G cg14067834 chr17:29058358 SUZ12P 0.69 6.86 0.35 3.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7772486 0.701 rs697056 chr6:146003897 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -5.72 -0.3 2.31e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs926392 0.932 rs4812360 chr20:37689259 A/G cg16355469 chr20:37678765 NA 0.38 5.99 0.31 5.36e-9 Dialysis-related mortality; LIHC cis rs74233809 1.000 rs9633712 chr10:104873761 G/C cg03493300 chr10:104813866 CNNM2 0.47 6.34 0.32 7.15e-10 Birth weight; LIHC cis rs7208859 0.673 rs12103588 chr17:29197460 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8060686 0.641 rs8058690 chr16:68136622 T/G cg05110241 chr16:68378359 PRMT7 -0.57 -6.61 -0.34 1.48e-10 HDL cholesterol;Metabolic syndrome; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02520104 chr13:80055217 NDFIP2 0.44 6.13 0.31 2.41e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs1552244 0.515 rs67626468 chr3:10161518 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC trans rs7618501 0.966 rs7372966 chr3:49788969 T/C cg21659725 chr3:3221576 CRBN -0.99 -19.64 -0.73 4.88e-58 Intelligence (multi-trait analysis); LIHC cis rs10540 1.000 rs61876323 chr11:462855 G/A cg03576123 chr11:487126 PTDSS2 -1.07 -8.63 -0.42 2.28e-16 Body mass index; LIHC cis rs796364 0.906 rs1658810 chr2:200816382 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 7.89 0.39 4.16e-14 Schizophrenia; LIHC cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.04 0.51 1.88e-24 Colorectal cancer; LIHC cis rs950169 0.840 rs62019457 chr15:85102142 T/C cg03959625 chr15:84868606 LOC388152 0.46 6.63 0.34 1.33e-10 Schizophrenia; LIHC cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg03517284 chr6:25882590 NA 0.56 7.65 0.38 2.11e-13 Blood metabolite levels; LIHC cis rs7617773 0.539 rs11706939 chr3:48383992 G/T cg11946769 chr3:48343235 NME6 0.62 7.55 0.38 3.92e-13 Coronary artery disease; LIHC cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg16145915 chr7:1198662 ZFAND2A -0.38 -9.31 -0.45 1.58e-18 Longevity;Endometriosis; LIHC cis rs35110281 0.811 rs1122873 chr21:45044672 G/C cg01579765 chr21:45077557 HSF2BP -0.34 -6.48 -0.33 3.23e-10 Mean corpuscular volume; LIHC cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1000083 0.834 rs1845656 chr5:96614105 C/T ch.5.96698337R chr5:96672581 NA 0.93 7.47 0.37 6.95e-13 Cisplatin-induced ototoxicity; LIHC cis rs599083 0.530 rs689179 chr11:68179166 A/G cg16797656 chr11:68205561 LRP5 -0.49 -7.7 -0.38 1.43e-13 Bone mineral density (spine); LIHC cis rs10463316 0.817 rs13355052 chr5:150802003 A/G cg03212797 chr5:150827313 SLC36A1 -0.41 -6.2 -0.32 1.6e-9 Metabolite levels (Pyroglutamine); LIHC cis rs3020736 0.500 rs1801311 chr22:42486723 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.38 -5.97 -0.31 6.02e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7937682 0.883 rs1789358 chr11:111474116 G/A cg22437258 chr11:111473054 SIK2 0.51 5.74 0.3 2.11e-8 Primary sclerosing cholangitis; LIHC cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg17971929 chr21:40555470 PSMG1 -0.52 -7.94 -0.39 2.91e-14 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06441946 chr5:145583671 RBM27 0.42 6.41 0.33 4.73e-10 Cognitive function; LIHC trans rs6598955 0.671 rs75517917 chr1:26612926 G/T cg07461501 chr17:79650226 HGS;ARL16 -0.71 -8.12 -0.4 8.51e-15 Obesity-related traits; LIHC cis rs1348850 0.958 rs11689550 chr2:178456298 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.45 0.53 6.57e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9916302 0.904 rs8066704 chr17:37477218 C/T cg03013999 chr17:37608204 MED1 -0.36 -6.06 -0.31 3.64e-9 Glomerular filtration rate (creatinine); LIHC cis rs7917772 0.502 rs10748827 chr10:104368336 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.78 0.57 7.68e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4665809 1.000 rs6704930 chr2:26325705 G/A cg04944784 chr2:26401820 FAM59B -0.65 -8.27 -0.41 3.05e-15 Gut microbiome composition (summer); LIHC cis rs12142240 0.738 rs67545510 chr1:46806242 G/T cg00530320 chr1:46809349 NSUN4 0.54 5.8 0.3 1.55e-8 Menopause (age at onset); LIHC cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg24642844 chr7:1081250 C7orf50 -0.61 -6.69 -0.34 9.28e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2033711 0.870 rs7408188 chr19:58939389 T/G cg00825309 chr19:58991885 ZNF446 -0.64 -10.19 -0.48 1.8e-21 Uric acid clearance; LIHC cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg11644478 chr21:40555479 PSMG1 0.74 8.98 0.44 1.92e-17 Cognitive function; LIHC cis rs2404602 0.735 rs283789 chr15:76777577 G/A cg03037974 chr15:76606532 NA 0.66 11.84 0.54 2.44e-27 Blood metabolite levels; LIHC cis rs5769765 0.955 rs5770750 chr22:50276828 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.2 0.45 3.71e-18 Schizophrenia; LIHC cis rs5769765 1.000 rs764813 chr22:50286172 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.15 -0.44 5.07e-18 Schizophrenia; LIHC cis rs2302190 0.882 rs7221464 chr17:56552353 A/T cg05425664 chr17:57184151 TRIM37 -0.49 -5.94 -0.31 6.91e-9 Vitamin D levels; LIHC cis rs1008375 0.932 rs3846356 chr4:17614176 C/T cg02297831 chr4:17616191 MED28 0.49 7.61 0.38 2.63e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg16434002 chr17:42200994 HDAC5 -0.52 -7.64 -0.38 2.25e-13 Total body bone mineral density; LIHC cis rs651907 0.535 rs34648996 chr3:101511202 A/G cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.86 -0.3 1.1e-8 Colorectal cancer; LIHC cis rs722599 0.847 rs2058919 chr14:75310812 C/G cg08847533 chr14:75593920 NEK9 -0.43 -7.07 -0.36 8.98e-12 IgG glycosylation; LIHC cis rs10267417 0.544 rs2072185 chr7:19748700 G/A cg07541023 chr7:19748670 TWISTNB 0.9 19.88 0.73 5.43e-59 Night sleep phenotypes; LIHC cis rs11734570 0.581 rs55958238 chr4:38604331 A/G cg18361445 chr4:38666374 KLF3;FLJ13197 0.53 7.32 0.37 1.83e-12 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1568889 0.838 rs1525717 chr11:28081205 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 13.84 0.6 6.95e-35 Bipolar disorder; LIHC cis rs7572733 0.534 rs1464209 chr2:198814396 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.7e-11 Dermatomyositis; LIHC cis rs311392 0.871 rs402088 chr8:55092805 A/G cg20636351 chr8:55087400 NA -0.38 -7.71 -0.38 1.41e-13 Pelvic organ prolapse (moderate/severe); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10130860 chr1:43124230 PPIH 0.49 6.59 0.34 1.65e-10 Lung function (FEV1/FVC); LIHC cis rs757081 0.667 rs12420958 chr11:17100432 G/T cg15432903 chr11:17409602 KCNJ11 -0.42 -5.88 -0.3 9.54e-9 Systolic blood pressure; LIHC cis rs2576037 0.523 rs590923 chr18:44404259 G/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.96 -0.31 6.36e-9 Personality dimensions; LIHC cis rs208520 0.954 rs72884027 chr6:66995044 T/G cg07460842 chr6:66804631 NA 0.68 7.38 0.37 1.22e-12 Exhaled nitric oxide output; LIHC cis rs2576037 0.526 rs3892820 chr18:44479558 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.49 -7.15 -0.36 5.23e-12 Personality dimensions; LIHC cis rs6450176 1.000 rs3776718 chr5:53298714 G/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2204008 0.837 rs7315255 chr12:37949279 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.72 0.5 2.63e-23 Bladder cancer; LIHC cis rs1059312 0.808 rs11059921 chr12:129289919 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.76 -16.52 -0.67 1.77e-45 Systemic lupus erythematosus; LIHC cis rs2153535 0.580 rs1932281 chr6:8473765 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs9326248 0.520 rs2735183 chr11:117015195 C/T cg01368799 chr11:117014884 PAFAH1B2 0.68 10.58 0.5 8e-23 Blood protein levels; LIHC cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.33e-30 Menopause (age at onset); LIHC cis rs72627509 0.904 rs3796529 chr4:57797414 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.56 -8.18 -0.4 5.51e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs79387448 0.626 rs80277428 chr2:103080056 G/A cg09003973 chr2:102972529 NA 1.15 8.97 0.44 2.04e-17 Gut microbiota (bacterial taxa); LIHC cis rs12477438 0.765 rs12468807 chr2:99691994 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -16.01 -0.65 1.99e-43 Chronic sinus infection; LIHC cis rs5769707 1.000 rs5769707 chr22:50013402 G/T cg07959070 chr22:50026188 C22orf34 -0.33 -8.63 -0.42 2.4e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7917772 0.503 rs11191325 chr10:104302933 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17401966 1.000 rs12132635 chr1:10430479 G/A cg19773385 chr1:10388646 KIF1B -0.51 -8.69 -0.43 1.49e-16 Hepatocellular carcinoma; LIHC cis rs875971 0.862 rs12537823 chr7:65720884 C/T cg18876405 chr7:65276391 NA 0.35 6.32 0.32 7.96e-10 Aortic root size; LIHC cis rs6459804 1.000 rs6459806 chr7:157510483 C/G cg05731713 chr7:157510257 PTPRN2 0.23 6.34 0.32 7.13e-10 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05787193 chr1:84543369 PRKACB -0.45 -6.05 -0.31 3.71e-9 Pancreatic cancer; LIHC cis rs11105298 0.891 rs4842654 chr12:89834428 T/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.37 -0.37 1.25e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs6840360 0.571 rs17360385 chr4:152587970 C/A cg22705602 chr4:152727874 NA -0.34 -6.45 -0.33 3.81e-10 Intelligence (multi-trait analysis); LIHC cis rs9733 0.596 rs72702573 chr1:150689050 C/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC trans rs6598955 0.671 rs10159433 chr1:26618370 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.21 -0.41 4.62e-15 Obesity-related traits; LIHC trans rs61931739 0.534 rs2667447 chr12:34133468 C/A cg26384229 chr12:38710491 ALG10B 0.45 6.33 0.32 7.81e-10 Morning vs. evening chronotype; LIHC cis rs17685 0.753 rs4728550 chr7:75670988 C/A cg04592579 chr7:75616294 TMEM120A -0.4 -6.83 -0.35 3.8e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs763121 0.853 rs9610986 chr22:39025277 T/C cg14440974 chr22:39074834 NA -0.42 -6.78 -0.34 5.18e-11 Menopause (age at onset); LIHC cis rs202126107 1 rs202126107 chr17:38006767 GCATATTATA/G cg11212589 chr17:38028394 ZPBP2 0.35 7.13 0.36 5.95e-12 Eosinophil percentage of white cells; LIHC cis rs7635838 0.722 rs6773963 chr3:11511975 G/A cg00170343 chr3:11313890 ATG7 0.41 6.33 0.32 7.73e-10 HDL cholesterol; LIHC cis rs4900538 0.855 rs72698602 chr14:102880454 T/C cg18135206 chr14:102964638 TECPR2 -0.71 -11.17 -0.52 6.51e-25 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9457247 0.624 rs2239826 chr6:167504880 T/C cg07741184 chr6:167504864 NA 0.36 8.73 0.43 1.13e-16 Crohn's disease; LIHC cis rs6001982 0.512 rs12159200 chr22:41042091 A/C cg14879645 chr22:41048474 NA 0.4 5.95 0.31 6.5e-9 Breast cancer; LIHC cis rs2710642 0.611 rs974345 chr2:62882774 C/T cg17519650 chr2:63277830 OTX1 0.52 7.52 0.38 4.73e-13 LDL cholesterol levels;LDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21618040 chr12:123921306 RILPL2 0.5 6.31 0.32 8.53e-10 Lung function (FEV1/FVC); LIHC cis rs9549328 0.800 rs9549621 chr13:113633579 G/A cg00071026 chr13:113650936 MCF2L -0.38 -5.93 -0.31 7.3e-9 Systolic blood pressure; LIHC cis rs743757 1.000 rs9835537 chr3:50464335 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.51 8.03 0.4 1.57e-14 Diastolic blood pressure; LIHC cis rs16958440 0.867 rs79395141 chr18:44695680 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs523522 0.962 rs11065145 chr12:120947419 A/G cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC cis rs12477438 0.520 rs4851188 chr2:99745898 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.6 11.19 0.52 5.77e-25 Chronic sinus infection; LIHC cis rs12980942 0.591 rs2304231 chr19:41762670 T/C cg25627403 chr19:41769009 HNRNPUL1 0.59 7.09 0.36 7.88e-12 Coronary artery disease; LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC trans rs7618501 1.000 rs7618519 chr3:49772708 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg19104784 chr15:81616677 STARD5 0.52 6.6 0.34 1.56e-10 Hepatitis; LIHC cis rs6429082 0.791 rs291394 chr1:235651682 A/G cg26050004 chr1:235667680 B3GALNT2 0.5 7.6 0.38 2.84e-13 Adiposity; LIHC cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg03806693 chr22:41940476 POLR3H 1.13 13.08 0.58 5.61e-32 Vitiligo; LIHC cis rs2921036 0.545 rs4840975 chr8:8363258 C/T cg06636001 chr8:8085503 FLJ10661 -0.51 -6.18 -0.32 1.78e-9 Neuroticism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05617927 chr15:83654886 FAM103A1 0.43 6.55 0.33 2.07e-10 Pancreatic cancer; LIHC cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg22963979 chr7:1858916 MAD1L1 -0.37 -5.87 -0.3 1.01e-8 Bipolar disorder and schizophrenia; LIHC cis rs68170813 0.559 rs80341862 chr7:106934731 C/G cg02696742 chr7:106810147 HBP1 -0.51 -5.91 -0.3 8.3e-9 Coronary artery disease; LIHC cis rs1005277 0.579 rs2021649 chr10:38392122 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs870825 0.616 rs7682557 chr4:185640773 A/G cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs950169 0.887 rs71395453 chr15:85113490 G/C cg03959625 chr15:84868606 LOC388152 0.44 6.02 0.31 4.52e-9 Schizophrenia; LIHC cis rs523522 0.962 rs10849754 chr12:120940418 A/C cg12219531 chr12:120966889 COQ5 0.67 13.22 0.58 1.57e-32 High light scatter reticulocyte count; LIHC cis rs1395 0.744 rs1975384 chr2:27542041 C/T cg22903471 chr2:27725779 GCKR -0.44 -6.42 -0.33 4.43e-10 Blood metabolite levels; LIHC trans rs2727020 0.757 rs7924526 chr11:49267043 G/A cg15704280 chr7:45808275 SEPT13 0.77 11.66 0.53 1.15e-26 Coronary artery disease; LIHC cis rs4665809 0.838 rs7565843 chr2:26292912 G/C cg27170947 chr2:26402098 FAM59B -0.65 -7.98 -0.4 2.22e-14 Gut microbiome composition (summer); LIHC cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg18230493 chr5:56204884 C5orf35 -0.47 -6.55 -0.33 2.08e-10 Initial pursuit acceleration; LIHC cis rs6089829 0.890 rs6062775 chr20:61663650 T/C cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs7772486 0.875 rs1960885 chr6:146325930 G/T cg23711669 chr6:146136114 FBXO30 0.6 10.46 0.49 2.08e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.540 rs736270 chr7:65428822 T/C cg00343986 chr7:65444356 GUSB 0.46 6.38 0.33 5.7e-10 Aortic root size; LIHC cis rs2635047 0.837 rs2571009 chr18:44650279 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.49 6.8 0.34 4.8e-11 Educational attainment; LIHC cis rs477692 0.673 rs10829600 chr10:131322051 G/C cg19680672 chr10:131412579 MGMT -0.38 -5.8 -0.3 1.47e-8 Response to temozolomide; LIHC cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg06640241 chr16:89574553 SPG7 0.87 16.22 0.66 2.71e-44 Multiple myeloma (IgH translocation); LIHC cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg24642844 chr7:1081250 C7orf50 -0.95 -9.36 -0.45 1.09e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2694917 0.625 rs799261 chr12:56924389 C/G cg15380473 chr2:11864427 NA 0.51 6.26 0.32 1.16e-9 Blood metabolite ratios; LIHC trans rs2009579 1 rs2009579 chr20:37881482 A/G cg00585698 chr12:123750864 CDK2AP1 -0.42 -6.05 -0.31 3.73e-9 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs12594515 0.967 rs12595138 chr15:45986108 G/C cg01629716 chr15:45996671 NA 0.52 9.6 0.46 1.77e-19 Waist circumference;Weight; LIHC trans rs2739330 0.760 rs1007888 chr22:24241101 C/T cg06437703 chr8:37914619 EIF4EBP1 -0.56 -8.49 -0.42 6.4e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6430585 0.646 rs12476116 chr2:136497199 A/G cg07169764 chr2:136633963 MCM6 1.17 16.32 0.66 1.13e-44 Corneal structure; LIHC cis rs12086130 0.892 rs72906810 chr1:51457200 A/G cg07174182 chr1:51127561 FAF1 -0.92 -9.85 -0.47 2.66e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.31 0.81 2.24e-80 Prudent dietary pattern; LIHC cis rs950169 0.580 rs35516100 chr15:85195430 C/T cg17507749 chr15:85114479 UBE2QP1 0.69 7.97 0.4 2.46e-14 Schizophrenia; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg16219491 chr6:26197733 HIST1H3D 0.53 5.72 0.3 2.34e-8 Gout;Renal underexcretion gout; LIHC cis rs77669868 0.929 rs3782002 chr11:114070563 A/T cg01914181 chr11:114070210 ZBTB16 0.65 9.07 0.44 9.62e-18 Monocyte percentage of white cells; LIHC trans rs4566648 0.593 rs28425691 chr4:84174626 A/G cg06219686 chr17:29421884 NF1 -0.52 -6.12 -0.31 2.53e-9 Monocyte count; LIHC cis rs5769765 0.865 rs10854860 chr22:50320029 G/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.41 -0.45 7.59e-19 Schizophrenia; LIHC cis rs6504950 0.566 rs7226272 chr17:53046447 G/A cg19360675 chr17:53046073 COX11;STXBP4 0.59 8.65 0.42 2.08e-16 Breast cancer; LIHC cis rs16958440 0.867 rs75481537 chr18:44719946 C/T cg17192377 chr18:44677553 HDHD2 0.91 8.68 0.42 1.64e-16 Sitting height ratio; LIHC cis rs6840360 0.593 rs10013612 chr4:152693622 A/G cg22705602 chr4:152727874 NA -0.4 -8.52 -0.42 5.04e-16 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.845 rs2042511 chr12:29408780 C/T cg14222432 chr12:29376421 FAR2 0.37 7.11 0.36 6.68e-12 QT interval; LIHC cis rs970821 0.966 rs1946585 chr8:124750741 A/G cg00283535 chr8:124749564 ANXA13 0.35 5.88 0.3 9.98e-9 Breast cancer; LIHC cis rs3008870 1.000 rs7511948 chr1:67430427 A/G cg02640540 chr1:67518911 SLC35D1 0.43 5.96 0.31 6.44e-9 Lymphocyte percentage of white cells; LIHC cis rs12431939 0.947 rs55974960 chr14:51633742 T/C cg23942311 chr14:51606299 NA -0.36 -5.92 -0.3 7.73e-9 Cancer; LIHC cis rs765787 0.530 rs16941017 chr15:45543281 T/C cg24006582 chr15:45444508 DUOX1 -0.49 -7.01 -0.35 1.27e-11 Uric acid levels; LIHC cis rs4908768 0.501 rs1463050 chr1:8597042 G/A cg20416874 chr1:8611966 RERE -0.71 -15.65 -0.65 5.22e-42 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1552244 0.882 rs13074282 chr3:10024699 T/G cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC trans rs4322600 0.963 rs12884672 chr14:88286529 A/G cg16008221 chr8:17823628 PCM1 -0.41 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs9916302 0.808 rs12943928 chr17:37611330 G/A cg00129232 chr17:37814104 STARD3 -0.42 -6.8 -0.35 4.72e-11 Glomerular filtration rate (creatinine); LIHC cis rs2832191 0.791 rs2832182 chr21:30481612 G/A cg08807101 chr21:30365312 RNF160 -0.63 -10.01 -0.48 7.61e-21 Dental caries; LIHC cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg25072359 chr17:41440525 NA 0.38 6.03 0.31 4.34e-9 Menopause (age at onset); LIHC cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -5.95 -0.31 6.76e-9 Bipolar disorder and schizophrenia; LIHC cis rs2204008 0.775 rs11514370 chr12:38305566 G/A cg26384229 chr12:38710491 ALG10B 0.55 7.59 0.38 3.12e-13 Bladder cancer; LIHC cis rs8103278 0.507 rs4802276 chr19:46260748 T/C cg02376097 chr19:46275166 DMPK 0.52 9.09 0.44 8.49e-18 Coronary artery disease; LIHC cis rs7131987 0.621 rs11050181 chr12:29467669 C/T cg00204748 chr12:29376779 FAR2 0.4 7.38 0.37 1.2e-12 QT interval; LIHC trans rs2749592 0.550 rs7917262 chr10:37874602 A/C cg17830980 chr10:43048298 ZNF37B 0.42 7.94 0.39 3.02e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs634534 0.561 rs655744 chr11:65776585 G/T cg02202077 chr11:65769826 EIF1AD;BANF1 -0.4 -6.09 -0.31 3.03e-9 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs4919694 1.000 rs12246689 chr10:104817031 C/T cg04362960 chr10:104952993 NT5C2 1.14 8.87 0.43 4.24e-17 Arsenic metabolism; LIHC cis rs9926296 0.609 rs4785714 chr16:89798404 G/T cg04287289 chr16:89883240 FANCA -0.5 -8.32 -0.41 2.06e-15 Vitiligo; LIHC cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC cis rs11122272 0.735 rs2009873 chr1:231499236 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.83 -0.51 1.06e-23 Hemoglobin concentration; LIHC cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.705 rs2486731 chr1:231532511 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.61 10.19 0.48 1.83e-21 Hemoglobin concentration; LIHC cis rs7208859 0.623 rs60890550 chr17:29030861 A/G cg14067834 chr17:29058358 SUZ12P 0.71 6.92 0.35 2.24e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10508774 1.000 rs12266925 chr10:32856445 A/G cg01819863 chr10:32635814 EPC1 0.65 6.1 0.31 2.87e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg03611732 chr10:21785697 C10orf114;MIR1915 0.5 6.09 0.31 3.03e-9 Glycated hemoglobin levels; LIHC cis rs4635969 0.718 rs27071 chr5:1346081 T/C cg07493874 chr5:1342172 CLPTM1L -0.46 -6.02 -0.31 4.46e-9 Testicular germ cell tumor;Testicular germ cell cancer; LIHC cis rs709400 0.894 rs61996721 chr14:104061352 G/A cg26031613 chr14:104095156 KLC1 1.13 14.74 0.62 2.07e-38 Body mass index; LIHC cis rs3008870 1.000 rs3008871 chr1:67419089 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.99 -16.18 -0.66 3.9e-44 Lymphocyte percentage of white cells; LIHC cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.86 8.12 0.4 8.83e-15 Platelet count; LIHC trans rs2243480 1.000 rs59794892 chr7:65415873 G/A cg10756647 chr7:56101905 PSPH 1.09 13.52 0.59 1.17e-33 Diabetic kidney disease; LIHC trans rs7246657 0.882 rs59224125 chr19:37963205 T/C cg10208301 chr11:6592745 DNHD1 0.45 6.54 0.33 2.3e-10 Coronary artery calcification; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03940137 chr1:200708937 CAMSAP1L1 0.42 6.11 0.31 2.74e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088813 1.000 rs6141548 chr20:33971085 A/G cg14752227 chr20:34000481 UQCC -0.4 -5.8 -0.3 1.53e-8 Height; LIHC cis rs11122272 0.735 rs2790878 chr1:231534390 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.27 0.45 2.1e-18 Hemoglobin concentration; LIHC cis rs6952808 1.000 rs4721121 chr7:1892565 A/G cg20295408 chr7:1910781 MAD1L1 -0.49 -7.1 -0.36 7.39e-12 Bipolar disorder and schizophrenia; LIHC cis rs7927592 0.913 rs948316 chr11:68309670 G/T cg20283391 chr11:68216788 NA -0.52 -7.87 -0.39 4.63e-14 Total body bone mineral density; LIHC cis rs9910055 0.530 rs8072954 chr17:42294722 G/A cg13607699 chr17:42295918 UBTF 0.66 11.68 0.53 9.17e-27 Total body bone mineral density; LIHC cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg22963979 chr7:1858916 MAD1L1 -0.38 -6.16 -0.32 2.08e-9 Bipolar disorder and schizophrenia; LIHC trans rs4906332 1.000 rs34347076 chr14:103955069 G/A cg17675199 chr6:35436792 RPL10A 0.35 6.89 0.35 2.76e-11 Coronary artery disease; LIHC cis rs7246657 0.943 rs4417644 chr19:37852472 A/G cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC cis rs2108622 0.727 rs3093193 chr19:15991914 C/G cg13772218 chr19:15982569 NA 0.37 7.51 0.38 5.06e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs9309473 1.000 rs10186501 chr2:73697844 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.87 -0.35 3.04e-11 Metabolite levels; LIHC cis rs919433 0.679 rs10203581 chr2:198515900 G/A cg10820045 chr2:198174542 NA 0.46 7.2 0.36 3.84e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.89 0.43 3.47e-17 Platelet count; LIHC cis rs9534288 0.762 rs9534264 chr13:46541673 T/A cg15192986 chr13:46630673 CPB2 -0.55 -8.45 -0.42 8.43e-16 Blood protein levels; LIHC cis rs6570726 0.935 rs436212 chr6:145849400 G/A cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs17152411 1.000 rs10901843 chr10:126638020 A/G cg07906193 chr10:126599966 NA 0.47 7.53 0.38 4.62e-13 Height; LIHC cis rs1552244 0.554 rs3846167 chr3:9996426 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.57 8.31 0.41 2.24e-15 Alzheimer's disease; LIHC cis rs9612 0.718 rs346531 chr19:44239927 T/C cg08581076 chr19:44259116 C19orf61 0.52 6.2 0.32 1.59e-9 Exhaled nitric oxide output; LIHC cis rs9303401 0.659 rs72828726 chr17:56951217 C/G cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.31 0.58 7.24e-33 Cognitive test performance; LIHC cis rs7408868 1.000 rs2074617 chr19:15276055 C/G cg09752223 chr19:15281200 NOTCH3 -0.37 -5.86 -0.3 1.07e-8 Pulse pressure; LIHC cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.02 0.31 4.58e-9 Menopause (age at onset); LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg06420487 chr17:61919686 SMARCD2 0.45 6.19 0.32 1.74e-9 Height; LIHC cis rs34779708 0.966 rs2045918 chr10:35418517 T/G cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.48e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs7246657 0.943 rs8111782 chr19:37867904 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC trans rs3749237 1.000 rs11710675 chr3:49751900 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.66 10.53 0.49 1.19e-22 Resting heart rate; LIHC cis rs539514 0.690 rs504273 chr13:76310850 C/T cg04757411 chr13:76259545 LMO7 -0.47 -8.3 -0.41 2.43e-15 Type 1 diabetes; LIHC cis rs1707322 0.686 rs2152078 chr1:46055600 C/T cg03146154 chr1:46216737 IPP -0.55 -8.88 -0.43 3.91e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs600806 0.778 rs11101962 chr1:110014187 A/T cg02415029 chr1:110025642 ATXN7L2 -0.44 -5.75 -0.3 1.95e-8 Intelligence (multi-trait analysis); LIHC cis rs4561483 0.801 rs33637 chr16:11989875 A/T cg08843971 chr16:11963173 GSPT1 -0.42 -8.45 -0.42 8.33e-16 Testicular germ cell tumor; LIHC cis rs66569888 0.789 rs17213510 chr2:106742778 T/C cg16099169 chr2:106886729 NA -0.81 -8.07 -0.4 1.19e-14 Facial morphology (factor 23); LIHC cis rs7208859 0.673 rs9899943 chr17:29223925 G/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12478296 0.786 rs72620862 chr2:243044787 T/C cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.09e-27 Obesity-related traits; LIHC cis rs2204008 0.837 rs1589395 chr12:38420405 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.48 0.42 6.79e-16 Bladder cancer; LIHC cis rs9326248 1.000 rs664971 chr11:117070857 A/G cg11861562 chr11:117069780 TAGLN -0.51 -8.45 -0.42 8.61e-16 Blood protein levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11240439 chr6:57087088 RAB23 -0.43 -6.17 -0.32 1.96e-9 Pancreatic cancer; LIHC cis rs75908454 1.000 rs74400382 chr6:169803042 T/C cg19338460 chr6:170058176 WDR27 -0.83 -7.52 -0.38 4.91e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs2380220 0.576 rs4498363 chr6:96042338 A/C cg04719120 chr6:96025338 MANEA 0.68 8.0 0.4 1.95e-14 Behavioural disinhibition (generation interaction); LIHC cis rs4319547 0.586 rs7956480 chr12:122817507 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.36 -0.37 1.4e-12 Body mass index; LIHC cis rs903552 1.000 rs8041563 chr15:102005824 G/C cg06707286 chr15:102010195 PCSK6 -0.44 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC cis rs950169 0.800 rs4842847 chr15:84931199 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 8.63 0.42 2.33e-16 Schizophrenia; LIHC cis rs6754311 0.731 rs309134 chr2:136755684 A/G cg07169764 chr2:136633963 MCM6 -0.7 -10.88 -0.51 6.88e-24 Mosquito bite size; LIHC cis rs7937890 0.732 rs7946902 chr11:14273308 C/T cg02251663 chr11:14281053 SPON1 0.46 6.38 0.33 5.9e-10 Mitochondrial DNA levels; LIHC cis rs10985070 0.504 rs2296077 chr9:123944943 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.21 0.32 1.5e-9 Rheumatoid arthritis; LIHC cis rs11077998 0.933 rs7215465 chr17:80532532 C/T cg10255544 chr17:80519551 FOXK2 0.48 8.53 0.42 4.96e-16 Reticulocyte fraction of red cells; LIHC cis rs8141529 0.719 rs5762880 chr22:29287816 T/G cg02153584 chr22:29168773 CCDC117 0.52 8.13 0.4 7.98e-15 Lymphocyte counts; LIHC cis rs3018712 0.590 rs4930585 chr11:68411347 T/C cg16797656 chr11:68205561 LRP5 -0.44 -5.83 -0.3 1.28e-8 Total body bone mineral density; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg21097698 chr4:76932399 ART3 -0.48 -6.81 -0.35 4.54e-11 Alcohol dependence; LIHC cis rs6545883 0.868 rs2518932 chr2:61801277 T/A cg14146966 chr2:61757674 XPO1 0.47 8.17 0.4 5.97e-15 Tuberculosis; LIHC cis rs17106184 1.000 rs72902763 chr1:51255320 T/C cg07174182 chr1:51127561 FAF1 -0.64 -6.89 -0.35 2.74e-11 Type 2 diabetes; LIHC cis rs7666738 0.791 rs7657399 chr4:98851861 T/C cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs7927592 0.763 rs10791982 chr11:68337664 T/G cg01657329 chr11:68192670 LRP5 0.5 7.35 0.37 1.5e-12 Total body bone mineral density; LIHC cis rs4853036 0.951 rs10165061 chr2:70146363 C/T cg02498382 chr2:70120550 SNRNP27 -0.42 -6.75 -0.34 6.19e-11 Colorectal or endometrial cancer; LIHC cis rs4319547 1.000 rs6489156 chr12:123100397 C/T cg23029597 chr12:123009494 RSRC2 -0.5 -7.06 -0.36 9.45e-12 Body mass index; LIHC cis rs875971 0.619 rs2302918 chr7:66000932 A/G cg14393609 chr7:65229607 NA 0.38 6.0 0.31 4.99e-9 Aortic root size; LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.56 -7.77 -0.39 9.43e-14 Lymphocyte counts; LIHC cis rs79040073 1.000 rs79040073 chr15:49330854 C/T cg04482760 chr15:49339272 SECISBP2L -0.49 -5.88 -0.3 9.76e-9 Lung cancer in ever smokers; LIHC cis rs7551222 0.634 rs11801289 chr1:204528969 G/C cg20240347 chr1:204465584 NA -0.35 -7.41 -0.37 1e-12 Schizophrenia; LIHC trans rs1814175 0.645 rs10444311 chr11:49986906 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23284646 chr4:17616339 MED28 0.45 6.17 0.32 1.89e-9 Lung function (FEV1/FVC); LIHC cis rs1055129 0.655 rs7216615 chr17:73833910 T/C cg19302996 chr17:73780495 UNK -0.6 -9.48 -0.46 4.46e-19 White matter hyperintensity burden; LIHC cis rs273218 1.000 rs156384 chr5:53371333 A/G ch.5.1024479R chr5:53302184 ARL15 0.66 10.68 0.5 3.48e-23 Migraine; LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg11342453 chr6:26196699 NA 0.53 5.92 0.3 7.83e-9 Gout;Renal underexcretion gout; LIHC trans rs61931739 0.500 rs10844862 chr12:34531965 A/T cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs2033711 0.870 rs3764534 chr19:58929136 G/A cg13877915 chr19:58951672 ZNF132 0.58 8.97 0.44 1.93e-17 Uric acid clearance; LIHC cis rs2953174 0.507 rs34568097 chr2:241540989 A/G cg07929629 chr2:241523174 NA 0.57 7.12 0.36 6.45e-12 Bipolar disorder; LIHC cis rs8049040 1.000 rs8049040 chr16:71472704 A/G cg06353428 chr16:71660113 MARVELD3 -0.55 -5.85 -0.3 1.16e-8 Blood protein levels; LIHC cis rs801193 0.935 rs11772264 chr7:66176387 T/C cg00343986 chr7:65444356 GUSB 0.39 5.76 0.3 1.85e-8 Aortic root size; LIHC cis rs10088262 0.629 rs1367829 chr8:124797135 A/G cg20713898 chr8:124780851 FAM91A1 -0.54 -7.35 -0.37 1.45e-12 Pancreatic cancer; LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00399650 chr7:141402322 KIAA1147 0.42 6.91 0.35 2.4e-11 Cognitive function; LIHC cis rs4638749 0.651 rs13385677 chr2:108826152 T/C cg25838818 chr2:108905173 SULT1C2 -0.4 -6.99 -0.35 1.47e-11 Blood pressure; LIHC cis rs933688 1.000 rs10041402 chr5:90738948 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 21.11 0.75 6.65e-64 Smoking behavior; LIHC cis rs6952809 0.692 rs10244138 chr7:2439587 C/A cg23289794 chr7:2394357 EIF3B -0.6 -5.95 -0.31 6.67e-9 Multiple sclerosis; LIHC cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg08923669 chr16:420230 MRPL28 -0.45 -6.29 -0.32 9.89e-10 Bone mineral density (spine);Bone mineral density; LIHC trans rs11098499 1.000 rs58601355 chr4:120186367 T/C cg25214090 chr10:38739885 LOC399744 0.5 7.55 0.38 4.05e-13 Corneal astigmatism; LIHC cis rs2760061 0.819 rs964941 chr1:228193857 G/A cg01200585 chr1:228362443 C1orf69 0.41 6.37 0.33 6.08e-10 Diastolic blood pressure; LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg02782426 chr3:40428986 ENTPD3 0.35 6.46 0.33 3.65e-10 Renal cell carcinoma; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg05560165 chr5:133450315 TCF7 -0.34 -6.1 -0.31 2.84e-9 Eotaxin levels; LIHC cis rs2439831 0.867 rs11856184 chr15:43919162 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.18 0.44 4.05e-18 Lung cancer in ever smokers; LIHC trans rs4566357 0.576 rs6750845 chr2:227911037 T/G cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.6e-9 Coronary artery disease; LIHC cis rs2991971 0.933 rs2356553 chr1:46009313 G/C cg24296786 chr1:45957014 TESK2 0.51 7.48 0.38 6.2e-13 High light scatter reticulocyte count; LIHC trans rs7618501 0.522 rs73077175 chr3:49774658 G/A cg21659725 chr3:3221576 CRBN -0.73 -12.03 -0.55 4.69e-28 Intelligence (multi-trait analysis); LIHC cis rs7326068 0.524 rs2497488 chr13:21201476 A/T cg27234864 chr13:21295941 IL17D 0.38 6.27 0.32 1.06e-9 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs12744310 0.830 rs12028010 chr1:41764471 T/C cg03962019 chr1:41807865 NA 0.38 6.18 0.32 1.79e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 7.28 0.37 2.35e-12 Platelet count; LIHC cis rs7903847 0.642 rs7088410 chr10:99135539 G/T cg08345082 chr10:99160200 RRP12 -0.37 -6.13 -0.31 2.37e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7923452 0.938 rs67812762 chr10:30759479 G/T cg25182066 chr10:30743637 MAP3K8 0.69 9.45 0.45 5.62e-19 Itch intensity from mosquito bite; LIHC cis rs2073300 1.000 rs2236021 chr20:23432528 A/G cg16736954 chr20:23401023 NAPB 0.51 5.73 0.3 2.26e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs35306767 0.807 rs34527494 chr10:935192 T/C cg26597838 chr10:835615 NA 1.46 16.71 0.67 3.08e-46 Eosinophil percentage of granulocytes; LIHC cis rs7587476 0.601 rs1129804 chr2:215674323 C/G cg04530015 chr2:215796436 ABCA12 0.46 7.7 0.38 1.51e-13 Neuroblastoma; LIHC cis rs7584330 0.554 rs79213383 chr2:238426890 A/G cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs12368653 0.651 rs2307097 chr12:58195801 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.46 -0.33 3.55e-10 Multiple sclerosis; LIHC cis rs1577917 1.000 rs10498958 chr6:86649705 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 10.57 0.5 9.04e-23 Response to antipsychotic treatment; LIHC cis rs7264396 0.943 rs224431 chr20:34153599 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.94 -0.35 2.02e-11 Total cholesterol levels; LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg06873352 chr17:61820015 STRADA 0.57 8.71 0.43 1.35e-16 Height; LIHC cis rs2251381 0.778 rs722013 chr21:30549245 G/T cg08807101 chr21:30365312 RNF160 0.76 9.88 0.47 2.05e-20 Selective IgA deficiency; LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.3e-14 Height; LIHC cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.1 -0.61 6.3e-36 Alzheimer's disease; LIHC cis rs10752881 1.000 rs4454510 chr1:182982303 A/G ch.1.3577855R chr1:183094577 LAMC1 -0.58 -10.25 -0.48 1.12e-21 Colorectal cancer; LIHC cis rs7520050 0.966 rs946529 chr1:46485548 G/T cg03146154 chr1:46216737 IPP -0.39 -6.38 -0.33 5.88e-10 Red blood cell count;Reticulocyte count; LIHC cis rs694739 0.687 rs11231771 chr11:64140642 T/G cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.08e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7772486 0.686 rs857883 chr6:145969214 G/T cg13319975 chr6:146136371 FBXO30 0.37 6.02 0.31 4.42e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7659604 0.539 rs11731917 chr4:122783233 G/A cg19748678 chr4:122722346 EXOSC9 0.67 11.13 0.52 9.02e-25 Type 2 diabetes; LIHC trans rs13325613 0.915 rs34745455 chr3:46267333 T/C cg26337592 chr1:153642686 ILF2 0.68 6.18 0.32 1.81e-9 Monocyte count; LIHC cis rs992157 0.965 rs62182826 chr2:219148723 C/A cg00012203 chr2:219082015 ARPC2 0.87 14.22 0.61 2.22e-36 Colorectal cancer; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg07332563 chr6:291687 DUSP22 -0.53 -7.65 -0.38 2.03e-13 Menopause (age at onset); LIHC cis rs8005677 1.000 rs4982710 chr14:23398902 C/T cg25600027 chr14:23388339 RBM23 -0.41 -5.88 -0.3 9.6e-9 Cognitive ability (multi-trait analysis); LIHC cis rs9399135 0.935 rs2150680 chr6:135347131 G/C cg24558204 chr6:135376177 HBS1L 0.42 6.82 0.35 4.14e-11 Red blood cell count; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg08280861 chr8:58055591 NA 0.49 6.13 0.31 2.38e-9 Developmental language disorder (linguistic errors); LIHC cis rs16828019 0.929 rs10524 chr1:41726473 T/C cg03387723 chr1:41708464 SCMH1 -0.44 -7.17 -0.36 4.67e-12 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.929 rs2121660 chr2:61653058 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.61 -0.38 2.72e-13 Tuberculosis; LIHC cis rs13392177 0.684 rs62185965 chr2:219073779 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.55 -7.82 -0.39 6.54e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs11673344 0.523 rs1667379 chr19:37492094 A/T cg27390819 chr19:37464633 NA -0.47 -6.15 -0.32 2.22e-9 Obesity-related traits; LIHC cis rs4555082 0.830 rs2735812 chr14:105727575 A/G cg06808227 chr14:105710500 BRF1 -0.61 -8.25 -0.41 3.44e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs597539 0.652 rs507520 chr11:68666054 C/T cg04772025 chr11:68637568 NA 0.48 6.15 0.32 2.14e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg05590025 chr7:65112418 INTS4L2 -0.57 -6.25 -0.32 1.2e-9 Diabetic kidney disease; LIHC cis rs7666738 0.546 rs3911415 chr4:98692401 T/A cg05340658 chr4:99064831 C4orf37 0.48 6.23 0.32 1.34e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs611744 0.647 rs6981420 chr8:109266694 T/G cg18478394 chr8:109455254 TTC35 0.42 7.24 0.36 3.07e-12 Dupuytren's disease; LIHC cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg27572855 chr1:25598939 RHD 0.41 8.94 0.44 2.46e-17 Erythrocyte sedimentation rate; LIHC cis rs10420951 0.617 rs3746176 chr19:18568951 C/G cg10790698 chr19:18539756 SSBP4 -0.42 -5.93 -0.31 7.23e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6542838 0.702 rs4851177 chr2:99535188 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -6.69 -0.34 9.06e-11 Fear of minor pain; LIHC cis rs2933343 0.859 rs789245 chr3:128583580 C/A cg25356066 chr3:128598488 ACAD9 0.55 7.01 0.35 1.29e-11 IgG glycosylation; LIHC cis rs929354 0.553 rs34498858 chr7:156931337 T/C cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.39e-27 Body mass index; LIHC cis rs2204008 0.548 rs2320740 chr12:38166421 G/A cg13010199 chr12:38710504 ALG10B 0.48 5.71 0.3 2.42e-8 Bladder cancer; LIHC cis rs7131987 0.868 rs737160 chr12:29429012 T/C cg14222432 chr12:29376421 FAR2 0.34 6.68 0.34 9.74e-11 QT interval; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg13409248 chr3:40428643 ENTPD3 0.46 7.91 0.39 3.64e-14 Renal cell carcinoma; LIHC cis rs4713118 0.527 rs35949862 chr6:28115367 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Parkinson's disease; LIHC cis rs6815814 0.898 rs17582830 chr4:38867427 A/G cg06935464 chr4:38784597 TLR10 0.39 5.82 0.3 1.38e-8 Breast cancer; LIHC cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg11062466 chr8:58055876 NA -0.46 -6.5 -0.33 2.86e-10 Developmental language disorder (linguistic errors); LIHC trans rs879568 0.789 rs4799432 chr18:34315042 C/T cg16486109 chr11:613632 IRF7 -0.42 -6.12 -0.31 2.5e-9 QRS duration; LIHC trans rs35110281 0.807 rs28840140 chr21:45039163 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.71 0.34 7.96e-11 Mean corpuscular volume; LIHC cis rs1707322 0.691 rs61784803 chr1:46179271 C/A cg03146154 chr1:46216737 IPP -0.6 -10.31 -0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2839186 0.587 rs35679325 chr21:47640980 A/G cg00815214 chr21:47717953 NA 0.34 5.72 0.3 2.36e-8 Testicular germ cell tumor; LIHC cis rs7772486 0.875 rs12194437 chr6:146411440 A/G cg05347473 chr6:146136440 FBXO30 0.38 5.99 0.31 5.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4908768 0.501 rs6577513 chr1:8702753 G/A cg20416874 chr1:8611966 RERE -0.62 -12.53 -0.56 6.54e-30 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs61712019 0.679 rs2861055 chr2:77716557 C/T cg11252801 chr2:77748917 LRRTM4 0.55 7.73 0.39 1.25e-13 Schizophrenia; LIHC cis rs9326248 0.954 rs4938349 chr11:117021923 C/T cg11861562 chr11:117069780 TAGLN 0.48 8.03 0.4 1.59e-14 Blood protein levels; LIHC cis rs427394 0.802 rs274718 chr5:6720988 G/T cg10857441 chr5:6722123 POLS -0.36 -6.25 -0.32 1.22e-9 Menopause (age at onset); LIHC cis rs13191362 0.810 rs13200053 chr6:163011443 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.63 5.88 0.3 9.7e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7107174 0.892 rs2510031 chr11:77969956 T/C cg02023728 chr11:77925099 USP35 0.45 8.76 0.43 9.18e-17 Testicular germ cell tumor; LIHC cis rs694739 0.628 rs10897487 chr11:64140704 C/T cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.08e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs6701037 0.875 rs1057301 chr1:175126524 T/C cg17845761 chr1:175162550 KIAA0040 -0.36 -5.88 -0.3 9.9e-9 Alcohol dependence; LIHC cis rs6952808 0.771 rs10950415 chr7:1914477 A/G cg02951883 chr7:2050386 MAD1L1 -0.52 -7.63 -0.38 2.34e-13 Bipolar disorder and schizophrenia; LIHC cis rs155076 1.000 rs261432 chr13:21865915 G/C cg11317459 chr13:21872234 NA -1.16 -13.08 -0.58 5.77e-32 White matter hyperintensity burden; LIHC cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg11764359 chr7:65958608 NA -0.57 -5.93 -0.31 7.25e-9 Diabetic kidney disease; LIHC cis rs910316 0.935 rs175422 chr14:75627319 T/A cg08847533 chr14:75593920 NEK9 -0.86 -17.71 -0.69 3.01e-50 Height; LIHC cis rs2070488 1.000 rs6772046 chr3:38479660 C/T cg24069376 chr3:38537580 EXOG 0.41 7.48 0.37 6.42e-13 Electrocardiographic conduction measures; LIHC cis rs2070433 0.752 rs2839220 chr21:47774330 G/C cg12379764 chr21:47803548 PCNT 0.75 10.53 0.49 1.18e-22 Lymphocyte counts; LIHC cis rs7264396 0.836 rs2010565 chr20:34182517 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -8.89 -0.43 3.7e-17 Total cholesterol levels; LIHC cis rs67460515 0.859 rs7610800 chr3:161002582 C/T cg17135325 chr3:160939158 NMD3 0.55 7.88 0.39 4.38e-14 Parkinson's disease; LIHC cis rs11577318 0.812 rs3795683 chr1:26632831 C/A cg18121669 chr1:26560928 CCDC21 0.51 8.04 0.4 1.5e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs8108269 1.000 rs8107236 chr19:46158436 A/G cg13320842 chr19:46175254 GIPR 0.41 7.74 0.39 1.16e-13 Type 2 diabetes; LIHC cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg06634786 chr22:41940651 POLR3H -0.77 -7.75 -0.39 1.09e-13 Vitiligo; LIHC cis rs7078219 0.505 rs7893840 chr10:101293341 T/C cg06854084 chr10:101292507 NKX2-3 -0.33 -6.09 -0.31 3.12e-9 Dental caries; LIHC cis rs796364 0.806 rs74266489 chr2:201005732 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs7953508 0.711 rs11107120 chr12:93985482 T/C cg18151635 chr12:93972918 NA -0.49 -7.6 -0.38 2.85e-13 Pubertal anthropometrics; LIHC cis rs3015497 0.624 rs3015488 chr14:51135309 A/G cg09863266 chr14:51125203 SAV1 -0.42 -5.85 -0.3 1.13e-8 Mean platelet volume; LIHC cis rs12477438 0.953 rs3851334 chr2:99794704 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -7.58 -0.38 3.3e-13 Chronic sinus infection; LIHC cis rs17401966 1.000 rs12130220 chr1:10359944 T/G cg19773385 chr1:10388646 KIF1B -0.48 -8.34 -0.41 1.79e-15 Hepatocellular carcinoma; LIHC cis rs2933343 0.729 rs813732 chr3:128619357 C/T cg25356066 chr3:128598488 ACAD9 0.54 7.39 0.37 1.11e-12 IgG glycosylation; LIHC cis rs6582630 0.555 rs1969362 chr12:38514843 C/T cg26384229 chr12:38710491 ALG10B 0.68 9.86 0.47 2.43e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs6137287 0.643 rs6047259 chr20:21098319 A/G cg04219410 chr20:21106687 PLK1S1 -0.33 -5.81 -0.3 1.41e-8 Height; LIHC cis rs7552404 0.731 rs17650138 chr1:76398887 C/T cg03433033 chr1:76189801 ACADM -0.58 -6.63 -0.34 1.3e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11718455 1.000 rs1524885 chr3:44031847 G/A cg08738300 chr3:44038990 NA 0.52 9.06 0.44 1.01e-17 Coronary artery disease; LIHC cis rs875971 1.000 rs778726 chr7:65828731 C/T cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg18402987 chr7:1209562 NA 0.41 5.71 0.3 2.46e-8 Longevity;Endometriosis; LIHC cis rs2303759 0.551 rs7249040 chr19:49790602 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.49 7.16 0.36 4.9e-12 Multiple sclerosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20679082 chr17:1090548 ABR 0.44 6.24 0.32 1.33e-9 Lung function (FEV1/FVC); LIHC cis rs12477438 0.765 rs62154638 chr2:99639584 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.67 -0.38 1.86e-13 Chronic sinus infection; LIHC cis rs3106136 0.586 rs28474924 chr4:95086345 G/C cg11021082 chr4:95130006 SMARCAD1 -0.34 -5.71 -0.3 2.45e-8 Capecitabine sensitivity; LIHC cis rs9611565 0.571 rs7364123 chr22:42216326 A/G cg06634786 chr22:41940651 POLR3H -0.55 -6.0 -0.31 5.02e-9 Vitiligo; LIHC cis rs2404602 0.575 rs11633309 chr15:76962349 C/A cg03037974 chr15:76606532 NA -0.51 -8.04 -0.4 1.44e-14 Blood metabolite levels; LIHC trans rs2243480 1.000 rs316317 chr7:65613637 G/T cg10756647 chr7:56101905 PSPH 1.1 13.4 0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs8180040 0.726 rs4682842 chr3:46982773 C/G cg02527881 chr3:46936655 PTH1R 0.35 6.78 0.34 5.38e-11 Colorectal cancer; LIHC cis rs17401966 0.964 rs17400510 chr1:10290421 T/C cg19773385 chr1:10388646 KIF1B -0.47 -8.19 -0.41 5.14e-15 Hepatocellular carcinoma; LIHC cis rs9616064 0.506 rs3747255 chr22:47074281 G/A cg05621596 chr22:47072043 GRAMD4 -0.75 -11.97 -0.54 8e-28 Urate levels in obese individuals; LIHC cis rs12701220 0.690 rs10243973 chr7:1064983 T/C cg16145915 chr7:1198662 ZFAND2A -0.3 -5.94 -0.31 6.87e-9 Bronchopulmonary dysplasia; LIHC trans rs4824093 0.610 rs77128035 chr22:50241024 C/T cg09872104 chr7:134855509 C7orf49 -0.76 -6.18 -0.32 1.85e-9 Amyotrophic lateral sclerosis (sporadic); LIHC trans rs1814175 0.645 rs28478790 chr11:50054322 C/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg06481639 chr22:41940642 POLR3H 0.61 5.89 0.3 9.45e-9 Vitiligo; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01505148 chr19:56170617 U2AF2 -0.41 -6.21 -0.32 1.5e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10463316 0.832 rs246484 chr5:150730938 T/C cg03212797 chr5:150827313 SLC36A1 -0.47 -7.09 -0.36 7.61e-12 Metabolite levels (Pyroglutamine); LIHC cis rs16828019 0.850 rs12027691 chr1:41462032 C/T cg03387723 chr1:41708464 SCMH1 -0.45 -6.66 -0.34 1.07e-10 Intelligence (multi-trait analysis); LIHC cis rs9467773 1.000 rs10946835 chr6:26533757 C/T cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC cis rs854765 0.647 rs4365346 chr17:17989373 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.34 6.3 0.32 9.34e-10 Total body bone mineral density; LIHC cis rs2153535 0.580 rs6597337 chr6:8531652 C/T cg23788917 chr6:8435910 SLC35B3 0.63 8.88 0.43 3.76e-17 Motion sickness; LIHC cis rs7772486 0.875 rs10457792 chr6:146412415 T/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.78 -0.3 1.69e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs13343954 0.518 rs7252086 chr19:33534929 T/C cg17764715 chr19:33622953 WDR88 0.49 6.87 0.35 3.12e-11 Colorectal cancer; LIHC trans rs1005277 0.522 rs7072977 chr10:37940440 C/A cg27523141 chr10:43048294 ZNF37B 0.37 6.51 0.33 2.74e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6963495 0.818 rs118134111 chr7:105161229 A/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -5.9 -0.3 8.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11971779 0.680 rs6946393 chr7:139106169 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs9303401 0.659 rs12944971 chr17:56988801 A/T cg25039879 chr17:56429692 SUPT4H1 0.81 9.27 0.45 2.19e-18 Cognitive test performance; LIHC cis rs9549367 0.577 rs3024711 chr13:113813268 A/G cg00898013 chr13:113819073 PROZ -0.43 -6.62 -0.34 1.38e-10 Platelet distribution width; LIHC cis rs17685 0.753 rs4732542 chr7:75663203 A/G cg04592579 chr7:75616294 TMEM120A 0.38 6.71 0.34 8.09e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs5753037 0.702 rs5752961 chr22:30188084 C/T cg01021169 chr22:30184971 ASCC2 -0.36 -6.94 -0.35 1.94e-11 Type 1 diabetes; LIHC cis rs2404602 0.735 rs2454454 chr15:76823647 A/G cg23625390 chr15:77176239 SCAPER -0.48 -8.04 -0.4 1.45e-14 Blood metabolite levels; LIHC cis rs11792861 0.566 rs966466 chr9:111851333 T/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.46 6.61 0.34 1.51e-10 Menarche (age at onset); LIHC cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg11764359 chr7:65958608 NA -0.55 -5.86 -0.3 1.08e-8 Diabetic kidney disease; LIHC cis rs919433 0.510 rs34631382 chr2:198390009 C/T cg03934865 chr2:198174659 NA 0.51 7.74 0.39 1.15e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2404602 0.552 rs11634428 chr15:77084582 T/C cg03037974 chr15:76606532 NA -0.51 -7.94 -0.39 2.92e-14 Blood metabolite levels; LIHC cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs362296 0.698 rs3095073 chr4:3263138 C/T cg06533319 chr4:3265114 C4orf44 0.32 6.15 0.32 2.19e-9 Parental longevity (mother's age at death); LIHC cis rs10779751 0.922 rs2746638 chr1:11278125 T/C cg08854313 chr1:11322531 MTOR 0.82 11.41 0.52 9.22e-26 Body mass index; LIHC cis rs1816752 0.776 rs7998843 chr13:25017285 T/C cg22771759 chr13:24902376 NA 0.31 6.54 0.33 2.3e-10 Obesity-related traits; LIHC cis rs9329289 0.632 rs2452187 chr10:2551147 C/G cg15501526 chr10:2543763 NA 0.25 6.19 0.32 1.76e-9 Age-related hearing impairment; LIHC cis rs600806 0.627 rs2359652 chr1:110008720 T/A cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.8 -0.39 7.43e-14 Intelligence (multi-trait analysis); LIHC cis rs2180341 1.000 rs6937287 chr6:127645719 T/A cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg08677398 chr8:58056175 NA 0.41 6.32 0.32 8.32e-10 Developmental language disorder (linguistic errors); LIHC cis rs7100689 0.754 rs10736339 chr10:82059970 G/C cg01528321 chr10:82214614 TSPAN14 0.87 11.96 0.54 8.55e-28 Post bronchodilator FEV1; LIHC cis rs7647973 0.626 rs12715437 chr3:49751856 T/C cg03060546 chr3:49711283 APEH 0.6 6.85 0.35 3.53e-11 Menarche (age at onset); LIHC cis rs6762 0.719 rs1130698 chr11:838542 C/T cg15787769 chr11:842744 TSPAN4;POLR2L -0.59 -6.87 -0.35 2.96e-11 Mean platelet volume; LIHC cis rs796364 1.000 rs281759 chr2:200787719 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.11 0.44 6.98e-18 Schizophrenia; LIHC trans rs2727020 0.704 rs4144700 chr11:49370834 C/A cg03929089 chr4:120376271 NA -0.84 -15.18 -0.63 3.68e-40 Coronary artery disease; LIHC trans rs1414896 0.692 rs4949948 chr1:95729060 A/T cg24483554 chr1:179544584 NPHS2 0.26 6.13 0.31 2.4e-9 Non-alcoholic fatty liver disease histology (AST); LIHC cis rs7072216 0.763 rs7923729 chr10:100169465 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs9596863 0.851 rs9568923 chr13:54357573 G/A ch.13.53330881F chr13:54432880 NA 0.45 6.03 0.31 4.21e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg05368731 chr17:41323189 NBR1 0.72 12.47 0.56 1.08e-29 Menopause (age at onset); LIHC cis rs1816752 0.905 rs8002215 chr13:24990367 A/G cg22771759 chr13:24902376 NA 0.33 6.67 0.34 1.01e-10 Obesity-related traits; LIHC cis rs2404602 0.583 rs11072580 chr15:76540231 G/A cg03037974 chr15:76606532 NA 0.86 21.24 0.75 2.02e-64 Blood metabolite levels; LIHC cis rs6684514 0.961 rs72710222 chr1:156285995 T/C cg16558208 chr1:156270281 VHLL 0.54 10.25 0.48 1.12e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs1355223 0.902 rs12802120 chr11:34747650 G/A cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.46 -0.33 3.61e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg14893161 chr1:205819251 PM20D1 0.68 9.89 0.47 1.95e-20 Menarche (age at onset); LIHC cis rs5760092 0.572 rs738806 chr22:24234172 A/G cg04234412 chr22:24373322 LOC391322 -0.5 -6.05 -0.31 3.86e-9 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs79149102 0.579 rs76518150 chr15:75292721 C/G cg17294928 chr15:75287854 SCAMP5 -0.52 -6.62 -0.34 1.38e-10 Lung cancer; LIHC cis rs2439831 0.850 rs12442297 chr15:44168470 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.04 0.31 3.92e-9 Lung cancer in ever smokers; LIHC cis rs7618501 0.633 rs4688758 chr3:50028385 G/A cg24110177 chr3:50126178 RBM5 -0.48 -7.66 -0.38 1.89e-13 Intelligence (multi-trait analysis); LIHC cis rs8103278 1.000 rs7258283 chr19:46335511 C/T cg02376097 chr19:46275166 DMPK -0.46 -6.95 -0.35 1.82e-11 Coronary artery disease; LIHC cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg14004847 chr7:1930337 MAD1L1 -0.51 -7.6 -0.38 2.85e-13 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18268492 chr10:99185986 PGAM1 -0.42 -6.27 -0.32 1.07e-9 Pancreatic cancer; LIHC cis rs6500602 0.739 rs4786502 chr16:4537104 T/C cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.79 0.3 1.61e-8 Schizophrenia; LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg04025307 chr7:1156635 C7orf50 0.67 11.85 0.54 2.32e-27 Longevity;Endometriosis; LIHC cis rs904251 0.864 rs2797801 chr6:37487161 A/G cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.39e-12 Cognitive performance; LIHC cis rs875971 0.862 rs4149461 chr7:65744732 T/C cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.03e-40 Aortic root size; LIHC cis rs6500602 0.647 rs4786514 chr16:4576798 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.49 7.57 0.38 3.5e-13 Schizophrenia; LIHC cis rs2408955 0.521 rs11168437 chr12:48566156 C/T cg21466736 chr12:48725269 NA -0.64 -9.2 -0.45 3.68e-18 Glycated hemoglobin levels; LIHC cis rs4721295 0.546 rs1637766 chr7:2204400 G/A cg04267008 chr7:1944627 MAD1L1 0.57 8.75 0.43 1.01e-16 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs7937890 0.559 rs2167160 chr11:14507449 C/A cg02886208 chr11:14281011 SPON1 -0.44 -6.17 -0.32 1.92e-9 Mitochondrial DNA levels; LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg05255149 chr17:80675120 FN3KRP 0.42 6.06 0.31 3.59e-9 Glycated hemoglobin levels; LIHC cis rs67460515 0.892 rs11711413 chr3:160998910 C/G cg17135325 chr3:160939158 NMD3 0.55 7.84 0.39 5.59e-14 Parkinson's disease; LIHC cis rs11025559 0.812 rs10766679 chr11:20509190 T/C cg19653624 chr11:20408972 PRMT3 -0.48 -6.27 -0.32 1.1e-9 Pursuit maintenance gain; LIHC cis rs6570726 0.791 rs9399558 chr6:145911730 T/C cg13319975 chr6:146136371 FBXO30 -0.42 -6.58 -0.34 1.76e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9419702 0.568 rs11156445 chr10:133542301 T/C cg04492858 chr10:133558786 NA 0.43 6.37 0.33 6.24e-10 Survival in rectal cancer; LIHC cis rs6500602 0.702 rs11645519 chr16:4538989 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 6.17 0.32 1.92e-9 Schizophrenia; LIHC cis rs4969178 0.931 rs6501208 chr17:76395038 A/T cg20026190 chr17:76395443 PGS1 0.45 7.15 0.36 5.19e-12 HDL cholesterol levels; LIHC cis rs2576037 0.583 rs2187091 chr18:44520048 T/C cg19077165 chr18:44547161 KATNAL2 -0.46 -7.02 -0.35 1.23e-11 Personality dimensions; LIHC cis rs1029738 0.500 rs10264441 chr7:22885014 C/A cg11367502 chr7:22862612 TOMM7 -0.37 -6.16 -0.32 2.02e-9 Fibrinogen levels; LIHC cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg08219700 chr8:58056026 NA 0.45 5.78 0.3 1.64e-8 Developmental language disorder (linguistic errors); LIHC cis rs920590 0.721 rs920587 chr8:19663339 C/A cg01411142 chr8:19674711 INTS10 0.51 7.95 0.4 2.7e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs4969178 0.965 rs2292642 chr17:76395430 C/T cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.01e-12 HDL cholesterol levels; LIHC cis rs7246657 0.765 rs10402455 chr19:37728707 G/A cg23950597 chr19:37808831 NA -0.51 -5.97 -0.31 5.78e-9 Coronary artery calcification; LIHC cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.53e-9 Menopause (age at onset); LIHC cis rs6430585 0.528 rs12474975 chr2:136702118 A/T cg07169764 chr2:136633963 MCM6 1.29 21.31 0.76 1.03e-64 Corneal structure; LIHC trans rs1814175 0.619 rs847644 chr11:49918418 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05505450 chr2:58273643 VRK2 0.43 6.55 0.33 2.14e-10 Pancreatic cancer; LIHC cis rs7615952 0.576 rs2276727 chr3:125826243 C/T cg05084668 chr3:125655381 ALG1L -0.41 -6.36 -0.33 6.49e-10 Blood pressure (smoking interaction); LIHC cis rs1577917 1.000 rs12192992 chr6:86609915 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.26 -0.37 2.55e-12 Response to antipsychotic treatment; LIHC cis rs61776719 0.520 rs12569027 chr1:38449163 C/T cg12658694 chr1:38397304 INPP5B 0.52 7.75 0.39 1.05e-13 Coronary artery disease; LIHC cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg21724239 chr8:58056113 NA 0.55 6.84 0.35 3.77e-11 Developmental language disorder (linguistic errors); LIHC cis rs1355223 0.902 rs12802323 chr11:34747739 G/A cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.46 -0.33 3.61e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs907683 0.583 rs10932803 chr2:220292739 A/T cg15015639 chr2:220282977 DES 0.35 8.4 0.41 1.19e-15 Resting heart rate; LIHC cis rs9399135 0.660 rs9376072 chr6:135280519 G/C cg24558204 chr6:135376177 HBS1L 0.39 6.52 0.33 2.46e-10 Red blood cell count; LIHC cis rs7927592 0.956 rs11228278 chr11:68308530 G/A cg01657329 chr11:68192670 LRP5 -0.47 -6.24 -0.32 1.31e-9 Total body bone mineral density; LIHC cis rs35110281 0.641 rs4819283 chr21:45083011 T/A cg04455712 chr21:45112962 RRP1B 0.51 8.78 0.43 8.13e-17 Mean corpuscular volume; LIHC cis rs2066819 1.000 rs59811639 chr12:56695954 C/T cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs3761847 0.651 rs1323472 chr9:123826335 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.42 5.86 0.3 1.08e-8 Rheumatoid arthritis; LIHC trans rs12478296 1.000 rs55717005 chr2:243041071 T/A cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.95e-15 Obesity-related traits; LIHC cis rs2257205 0.667 rs4453568 chr17:56934543 A/G cg05425664 chr17:57184151 TRIM37 -0.61 -6.67 -0.34 1.05e-10 Pancreatic cancer; LIHC cis rs4409675 0.549 rs72872888 chr1:28239809 G/A cg23691781 chr1:28212827 C1orf38 0.32 7.36 0.37 1.41e-12 Corneal astigmatism; LIHC cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg15691649 chr6:25882328 NA -0.56 -8.21 -0.41 4.44e-15 Blood metabolite levels; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg16132339 chr22:24313637 DDTL;DDT 0.73 13.83 0.6 7.65e-35 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2836974 0.563 rs6517522 chr21:40553845 T/C cg11644478 chr21:40555479 PSMG1 0.52 7.47 0.37 6.87e-13 Cognitive function; LIHC cis rs7617480 0.648 rs9864243 chr3:48982732 G/A cg20833759 chr3:49053208 WDR6;DALRD3 0.54 6.45 0.33 3.92e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24447660 chr3:127872092 EEFSEC 0.45 6.55 0.33 2.11e-10 Cognitive function; LIHC cis rs9818758 0.607 rs35283189 chr3:49113668 T/C cg06212747 chr3:49208901 KLHDC8B -0.69 -5.91 -0.3 8.11e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg12311636 chr6:118886798 C6orf204 -0.54 -6.38 -0.33 5.74e-10 Diastolic blood pressure; LIHC cis rs3981351 0.797 rs3814231 chr10:115481018 A/G cg24846397 chr10:115438155 CASP7 0.44 6.65 0.34 1.13e-10 Obesity-related traits; LIHC cis rs801193 0.569 rs11761542 chr7:66218196 G/A cg11764359 chr7:65958608 NA 0.75 12.68 0.57 1.77e-30 Aortic root size; LIHC cis rs1865760 0.566 rs9295686 chr6:26081983 G/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.65 0.38 2e-13 Bipolar disorder; LIHC cis rs2404602 0.672 rs35374222 chr15:77071394 G/T cg23625390 chr15:77176239 SCAPER -0.54 -9.01 -0.44 1.46e-17 Blood metabolite levels; LIHC cis rs11628318 0.614 rs7145737 chr14:103121784 T/A cg23461800 chr14:103021989 NA 0.42 5.83 0.3 1.31e-8 Platelet count; LIHC cis rs2380220 0.541 rs72928283 chr6:96082490 A/C cg04719120 chr6:96025338 MANEA -0.7 -7.91 -0.39 3.52e-14 Behavioural disinhibition (generation interaction); LIHC cis rs9733 0.596 rs6681990 chr1:150695929 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs7044106 0.791 rs7036196 chr9:123479457 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.12 0.52 1.02e-24 Hip circumference adjusted for BMI; LIHC cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg21782813 chr7:2030301 MAD1L1 0.47 8.05 0.4 1.41e-14 Bipolar disorder and schizophrenia; LIHC cis rs2731664 0.792 rs335434 chr5:176867276 A/G cg23176889 chr5:176863531 GRK6 -0.66 -11.72 -0.54 6.8e-27 Intelligence (multi-trait analysis); LIHC cis rs7223966 0.921 rs11655493 chr17:61733052 C/T cg05941027 chr17:61774174 LIMD2 0.32 6.53 0.33 2.43e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs473651 0.777 rs550890 chr2:239332555 G/A cg18131467 chr2:239335373 ASB1 0.84 13.87 0.6 5.23e-35 Multiple system atrophy; LIHC trans rs17685 0.753 rs1104879 chr7:75685568 C/T cg19862616 chr7:65841803 NCRNA00174 0.9 18.67 0.71 3.79e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.51 -0.38 5.05e-13 Lymphocyte counts; LIHC cis rs3770081 1.000 rs57083584 chr2:86283648 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.84 -8.17 -0.4 6.05e-15 Facial emotion recognition (sad faces); LIHC cis rs7772486 0.790 rs9497431 chr6:146248177 T/C cg13319975 chr6:146136371 FBXO30 0.39 6.23 0.32 1.4e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs875971 1.000 rs778726 chr7:65828731 C/T cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs55665837 1.000 rs11023214 chr11:14436259 G/C cg19336497 chr11:14380999 RRAS2 -0.46 -8.5 -0.42 5.91e-16 Vitamin D levels; LIHC cis rs8062405 0.691 rs11646653 chr16:28922149 C/T cg00204512 chr16:28754710 NA -0.33 -6.13 -0.31 2.43e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs9929218 0.954 rs2961 chr16:68818903 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.67 -0.42 1.8e-16 Colorectal cancer; LIHC cis rs2257205 0.667 rs7342862 chr17:56816561 A/G cg12560992 chr17:57184187 TRIM37 0.71 7.78 0.39 8.76e-14 Pancreatic cancer; LIHC trans rs208520 1.000 rs208521 chr6:66953625 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.57 -0.33 1.83e-10 Exhaled nitric oxide output; LIHC cis rs6582630 0.519 rs11609739 chr12:38547969 G/A cg13010199 chr12:38710504 ALG10B 0.58 6.93 0.35 2.09e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs10089 1.000 rs10064357 chr5:127417272 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.6 0.34 1.58e-10 Ileal carcinoids; LIHC cis rs7572733 0.515 rs11887138 chr2:198805838 T/A cg10820045 chr2:198174542 NA 0.48 7.47 0.37 6.93e-13 Dermatomyositis; LIHC cis rs11190604 1.000 rs2495753 chr10:102325640 C/T cg07080220 chr10:102295463 HIF1AN 0.53 7.18 0.36 4.49e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.87 0.3 1.05e-8 Menopause (age at onset); LIHC trans rs1728785 1.000 rs1645979 chr16:68603660 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.33 0.32 7.62e-10 Ulcerative colitis; LIHC cis rs12479064 0.724 rs4851203 chr2:99986932 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.6 -7.56 -0.38 3.65e-13 Chronic sinus infection; LIHC cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg17691542 chr6:26056736 HIST1H1C 0.39 5.9 0.3 8.77e-9 Height; LIHC cis rs2279817 0.863 rs12757678 chr1:17983680 G/C cg21791023 chr1:18019539 ARHGEF10L -0.66 -7.36 -0.37 1.34e-12 Neuroticism; LIHC cis rs243505 0.762 rs734004 chr7:148505460 C/G cg09806900 chr7:148480153 CUL1 0.44 6.73 0.34 7e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7296418 0.663 rs28450974 chr12:123861420 G/A cg05973401 chr12:123451056 ABCB9 0.41 6.28 0.32 1.02e-9 Platelet count; LIHC cis rs4638749 0.677 rs2198471 chr2:108844069 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -5.96 -0.31 6.23e-9 Blood pressure; LIHC cis rs6545883 0.965 rs1992765 chr2:61751333 A/G cg14146966 chr2:61757674 XPO1 0.48 8.51 0.42 5.37e-16 Tuberculosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27113440 chr11:22214386 ANO5 -0.45 -6.04 -0.31 4.04e-9 Pancreatic cancer; LIHC cis rs4638749 0.677 rs10185601 chr2:108828278 A/G cg25838818 chr2:108905173 SULT1C2 -0.39 -6.71 -0.34 8.07e-11 Blood pressure; LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.790 rs6917135 chr6:146152426 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.49 0.53 4.8e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08052302 chr7:76178628 LOC100133091 0.51 6.23 0.32 1.33e-9 Hepatitis; LIHC trans rs11088226 0.541 rs75873023 chr21:33910658 G/A cg09050820 chr6:167586206 TCP10L2 0.6 10.13 0.48 2.83e-21 Gastritis; LIHC cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg18252515 chr7:66147081 NA -1.24 -16.13 -0.66 6.34e-44 Diabetic kidney disease; LIHC trans rs2727020 0.521 rs937430 chr11:49542457 A/G cg15704280 chr7:45808275 SEPT13 0.78 11.77 0.54 4.55e-27 Coronary artery disease; LIHC trans rs1814175 0.541 rs12287397 chr11:49819799 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.64 -0.79 6.27e-74 Height; LIHC cis rs8017423 0.967 rs55962513 chr14:90729460 C/G cg04374321 chr14:90722782 PSMC1 0.78 15.26 0.64 1.75e-40 Mortality in heart failure; LIHC cis rs611744 0.967 rs597992 chr8:109193808 A/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs2404602 1.000 rs2404741 chr15:76851735 C/T cg23625390 chr15:77176239 SCAPER 0.43 7.23 0.36 3.27e-12 Blood metabolite levels; LIHC cis rs7306456 0.623 rs10902513 chr12:132693487 A/G cg00155535 chr12:132671473 NA 0.34 6.18 0.32 1.78e-9 Anti-saccade response; LIHC cis rs8044995 0.706 rs111948678 chr16:68255959 G/A cg09835421 chr16:68378352 PRMT7 -0.52 -5.98 -0.31 5.58e-9 Schizophrenia; LIHC cis rs1003719 0.708 rs2000417 chr21:38502868 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.23 -0.52 4.16e-25 Eye color traits; LIHC cis rs896854 1.000 rs896854 chr8:95960511 T/C cg23172400 chr8:95962367 TP53INP1 -0.43 -10.27 -0.49 9.53e-22 Type 2 diabetes; LIHC cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg06481639 chr22:41940642 POLR3H 0.72 7.43 0.37 8.51e-13 Vitiligo; LIHC cis rs9611519 0.857 rs4820434 chr22:41637119 G/T cg06634786 chr22:41940651 POLR3H -0.58 -6.25 -0.32 1.23e-9 Neuroticism; LIHC cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg18252515 chr7:66147081 NA 1.27 16.79 0.67 1.38e-46 Diabetic kidney disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19912883 chr2:87140809 RGPD2 -0.39 -6.18 -0.32 1.86e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 0.752 rs11488313 chr1:46224780 G/C cg03146154 chr1:46216737 IPP 0.56 8.99 0.44 1.78e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs116095464 0.558 rs10052012 chr5:231908 T/C cg22496380 chr5:211416 CCDC127 -1.02 -10.51 -0.49 1.47e-22 Breast cancer; LIHC cis rs8192282 0.739 rs4845648 chr1:154514338 A/T cg16683920 chr1:154474344 TDRD10;SHE 0.52 6.33 0.32 7.65e-10 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); LIHC cis rs11583043 1.000 rs6700743 chr1:101447384 A/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.12 0.31 2.57e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs921968 0.678 rs689116 chr2:219433888 C/A cg02985541 chr2:219472218 PLCD4 0.44 8.29 0.41 2.53e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs79387448 0.745 rs7576324 chr2:103142994 G/A cg09003973 chr2:102972529 NA 0.82 7.18 0.36 4.41e-12 Gut microbiota (bacterial taxa); LIHC cis rs7131987 0.903 rs7308125 chr12:29425211 T/C cg14222432 chr12:29376421 FAR2 0.37 7.02 0.35 1.23e-11 QT interval; LIHC cis rs1707322 1.000 rs7547284 chr1:46319565 C/G cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg13047869 chr3:10149882 C3orf24 0.54 6.49 0.33 2.99e-10 Alzheimer's disease; LIHC trans rs916888 0.821 rs199514 chr17:44856881 G/A cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg23205692 chr1:25664452 TMEM50A 0.39 6.23 0.32 1.37e-9 Plateletcrit;Mean corpuscular volume; LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg09417038 chr21:47716443 C21orf57 -0.56 -8.63 -0.42 2.41e-16 Testicular germ cell tumor; LIHC cis rs60871478 1.000 rs34761279 chr7:794471 A/G cg27478167 chr7:817139 HEATR2 -0.51 -6.79 -0.34 4.99e-11 Cerebrospinal P-tau181p levels; LIHC cis rs9534288 0.730 rs7985754 chr13:46581287 G/A cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs929354 1.000 rs1182377 chr7:157048403 T/C cg17757837 chr7:157058334 UBE3C -0.84 -14.14 -0.61 4.46e-36 Body mass index; LIHC cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg13395646 chr4:1353034 KIAA1530 -0.52 -8.52 -0.42 5.08e-16 Obesity-related traits; LIHC cis rs12477438 0.834 rs10179043 chr2:99687490 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.72 -0.54 7e-27 Chronic sinus infection; LIHC cis rs7662987 0.517 rs3018048 chr4:100005538 C/T cg12011299 chr4:100065546 ADH4 0.68 11.08 0.51 1.43e-24 Smoking initiation; LIHC cis rs9914988 0.943 rs9915673 chr17:27132893 G/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.86 -0.35 3.23e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7568458 0.684 rs1048740 chr2:85764966 A/T cg02493740 chr2:85810744 VAMP5 -0.47 -7.84 -0.39 5.6e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7617480 0.648 rs4974083 chr3:49000626 A/G cg07636037 chr3:49044803 WDR6 0.75 8.93 0.43 2.65e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs2016586 0.929 rs4821439 chr22:36114263 C/T cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 7.96e-10 Body mass index; LIHC cis rs882732 1.000 rs12586297 chr14:95032394 G/A cg14866387 chr14:95027382 SERPINA4 -0.46 -6.82 -0.35 4.04e-11 Blood protein levels; LIHC cis rs16828019 0.852 rs12742803 chr1:41648131 G/A cg03387723 chr1:41708464 SCMH1 -0.45 -7.23 -0.36 3.13e-12 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg21448741 chr8:58168803 NA 0.38 6.12 0.31 2.54e-9 Developmental language disorder (linguistic errors); LIHC cis rs1461503 0.809 rs7121955 chr11:122845478 A/T cg14473756 chr11:122847823 NA -0.35 -6.22 -0.32 1.42e-9 Menarche (age at onset); LIHC cis rs703842 1.000 rs10747783 chr12:58176614 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.86 14.25 0.61 1.74e-36 Multiple sclerosis; LIHC cis rs35110281 0.805 rs4818855 chr21:45038951 C/T cg21573476 chr21:45109991 RRP1B -0.48 -9.39 -0.45 8.68e-19 Mean corpuscular volume; LIHC cis rs7296418 0.816 rs1790096 chr12:123710364 C/T cg00376283 chr12:123451042 ABCB9 0.69 11.31 0.52 1.99e-25 Platelet count; LIHC trans rs6539288 0.803 rs10778517 chr12:107341664 G/T cg04226365 chr6:44355287 CDC5L 0.39 6.21 0.32 1.53e-9 Total body bone mineral density; LIHC cis rs6831352 0.918 rs2851253 chr4:100043505 G/T cg12011299 chr4:100065546 ADH4 -0.58 -10.1 -0.48 3.65e-21 Alcohol dependence; LIHC cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg07424592 chr7:64974309 NA -0.8 -9.08 -0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs7662987 0.517 rs2034696 chr4:100024322 C/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs6504950 0.800 rs7208123 chr17:53006339 G/A cg10237252 chr17:52977213 TOM1L1 -0.35 -6.15 -0.32 2.15e-9 Breast cancer; LIHC cis rs3781458 0.803 rs7088656 chr10:126324077 G/A cg20435097 chr10:126320824 FAM53B 0.72 13.39 0.59 3.75e-33 Male-pattern baldness; LIHC cis rs875971 0.964 rs11765965 chr7:65842221 A/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs6088590 0.735 rs2273684 chr20:33529766 G/T cg08999081 chr20:33150536 PIGU -0.48 -8.07 -0.4 1.22e-14 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07562458 chr1:224622430 WDR26 0.51 6.39 0.33 5.55e-10 Lung function (FEV1/FVC); LIHC cis rs611744 0.967 rs584716 chr8:109178634 A/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg07636037 chr3:49044803 WDR6 0.75 12.41 0.56 1.92e-29 Menarche (age at onset); LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg17158414 chr2:27665306 KRTCAP3 -0.42 -5.76 -0.3 1.83e-8 Total body bone mineral density; LIHC cis rs644799 1.000 rs500054 chr11:95593806 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 16.72 0.67 2.8e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2933343 0.729 rs789231 chr3:128602847 A/G cg25356066 chr3:128598488 ACAD9 0.55 7.69 0.38 1.55e-13 IgG glycosylation; LIHC cis rs9300255 0.602 rs1727314 chr12:123640664 C/A cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs4819052 0.851 rs1056100 chr21:46678711 A/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.84 0.39 5.6e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg13047869 chr3:10149882 C3orf24 0.41 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs9549367 0.826 rs35306827 chr13:113869045 G/A cg18105134 chr13:113819100 PROZ -0.66 -11.47 -0.53 5.68e-26 Platelet distribution width; LIHC cis rs7191439 0.674 rs4782429 chr16:88792097 A/G cg27087555 chr16:88793112 FAM38A -1.29 -12.91 -0.57 2.55e-31 Plateletcrit; LIHC cis rs7911264 0.905 rs7918084 chr10:94429467 C/T cg25506282 chr10:94462361 NA 0.39 5.91 0.3 8.45e-9 Inflammatory bowel disease; LIHC cis rs9303280 0.967 rs1031460 chr17:38072247 T/G cg11212589 chr17:38028394 ZPBP2 -0.34 -6.65 -0.34 1.16e-10 Self-reported allergy; LIHC cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg25072359 chr17:41440525 NA 0.37 5.95 0.31 6.5e-9 Menopause (age at onset); LIHC trans rs12753920 0.562 rs7549158 chr1:92610211 A/T cg15668468 chr10:118892869 VAX1 0.42 6.1 0.31 2.79e-9 Systemic lupus erythematosus; LIHC cis rs9309473 1.000 rs10496193 chr2:73773503 G/A cg20560298 chr2:73613845 ALMS1 -0.53 -6.67 -0.34 1.04e-10 Metabolite levels; LIHC cis rs10870270 0.956 rs10870281 chr10:133762642 G/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.84 -0.57 4.5e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg08888203 chr3:10149979 C3orf24 0.55 6.09 0.31 3.05e-9 Alzheimer's disease; LIHC cis rs79057730 0.527 rs35316052 chr7:802954 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.86 9.62 0.46 1.53e-19 Initial pursuit acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04324509 chr3:101295624 PCNP 0.38 6.5 0.33 2.85e-10 Longevity; LIHC cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg06453172 chr10:134556979 INPP5A -0.62 -7.87 -0.39 4.85e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2354432 0.556 rs7520661 chr1:146793149 A/G cg25205988 chr1:146714368 CHD1L -0.87 -10.69 -0.5 3.27e-23 Mitochondrial DNA levels; LIHC cis rs3820068 0.603 rs2236215 chr1:15892415 A/C cg17385448 chr1:15911702 AGMAT 0.37 6.24 0.32 1.27e-9 Systolic blood pressure; LIHC cis rs7258465 1.000 rs2007981 chr19:18567555 C/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.69 -0.38 1.58e-13 Breast cancer; LIHC cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg05025164 chr4:1340916 KIAA1530 -0.4 -6.1 -0.31 2.92e-9 Obesity-related traits; LIHC trans rs877282 0.755 rs1769242 chr10:787896 T/C cg22713356 chr15:30763199 NA 1.21 11.49 0.53 4.56e-26 Uric acid levels; LIHC cis rs4243830 0.850 rs12029123 chr1:6607142 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 1.0 12.18 0.55 1.36e-28 Body mass index; LIHC cis rs1559088 0.948 rs10410778 chr19:33592301 C/A cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1882538 0.901 rs35284403 chr7:132948884 T/C cg10665199 chr7:133106180 EXOC4 0.51 7.94 0.39 2.87e-14 Intelligence (multi-trait analysis); LIHC cis rs4820539 0.933 rs2267004 chr22:23459863 G/A cg14186256 chr22:23484241 RTDR1 0.93 18.77 0.71 1.5e-54 Bone mineral density; LIHC trans rs2727020 1.000 rs2727020 chr11:49111407 C/G cg18944383 chr4:111397179 ENPEP -0.27 -6.09 -0.31 3.07e-9 Coronary artery disease; LIHC cis rs9814567 0.806 rs6799543 chr3:134216139 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.22 -0.55 1e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs986417 1.000 rs1254270 chr14:60843134 G/T cg27398547 chr14:60952738 C14orf39 -0.79 -9.02 -0.44 1.36e-17 Gut microbiota (bacterial taxa); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21194911 chr19:44716733 ZNF227 0.46 6.18 0.32 1.86e-9 Lung function (FEV1/FVC); LIHC cis rs17401966 0.964 rs34215045 chr1:10361679 G/A cg15208524 chr1:10270712 KIF1B 0.46 6.75 0.34 6.34e-11 Hepatocellular carcinoma; LIHC cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg23758822 chr17:41437982 NA 0.92 17.07 0.68 1.09e-47 Menopause (age at onset); LIHC cis rs11864453 1.000 rs7185407 chr16:72034957 A/T cg01557791 chr16:72042693 DHODH 0.77 11.96 0.54 9e-28 Fibrinogen levels; LIHC cis rs2066819 1.000 rs59811639 chr12:56695954 C/T cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs10131894 0.575 rs1860935 chr14:75432464 G/A cg11812906 chr14:75593930 NEK9 0.63 10.82 0.51 1.14e-23 Coronary artery disease; LIHC cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.37 0.41 1.55e-15 Platelet count; LIHC cis rs1691799 0.867 rs6581677 chr12:66770379 C/G cg16791601 chr12:66731901 HELB -0.5 -10.71 -0.5 2.79e-23 White blood cell count (basophil); LIHC cis rs7945705 0.747 rs2568020 chr11:8994715 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -7.08 -0.36 8.37e-12 Hemoglobin concentration; LIHC cis rs782590 0.774 rs782630 chr2:55899425 T/C cg18811423 chr2:55921094 PNPT1 0.88 14.01 0.6 1.47e-35 Metabolic syndrome; LIHC cis rs7208859 0.673 rs73263755 chr17:29198972 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9911578 0.900 rs717828 chr17:56535932 A/G cg05425664 chr17:57184151 TRIM37 -0.57 -8.52 -0.42 5.22e-16 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg11494091 chr17:61959527 GH2 0.45 8.27 0.41 3.05e-15 Prudent dietary pattern; LIHC cis rs3823572 0.564 rs1986870 chr7:133660109 A/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs17345786 0.511 rs12639028 chr3:101346033 G/C cg11279151 chr3:101281821 RG9MTD1 -0.43 -6.47 -0.33 3.41e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs4654899 0.758 rs7530739 chr1:21447480 C/A cg08539965 chr1:21396338 EIF4G3 0.33 5.86 0.3 1.12e-8 Superior frontal gyrus grey matter volume; LIHC cis rs2439831 0.681 rs484029 chr15:43619560 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.76 11.56 0.53 2.6e-26 Lung cancer in ever smokers; LIHC trans rs8099121 0.585 rs9951289 chr18:4982797 G/C cg15792134 chr6:169051418 SMOC2 -0.36 -6.13 -0.31 2.42e-9 Schizophrenia; LIHC cis rs6088580 0.634 rs6088498 chr20:33020446 A/G cg08999081 chr20:33150536 PIGU 0.67 13.65 0.59 3.69e-34 Glomerular filtration rate (creatinine); LIHC cis rs10751667 0.857 rs6597952 chr11:991109 C/G cg06064525 chr11:970664 AP2A2 -0.49 -12.17 -0.55 1.5e-28 Alzheimer's disease (late onset); LIHC cis rs4319547 0.656 rs10773075 chr12:122814236 G/A cg23029597 chr12:123009494 RSRC2 -0.52 -7.4 -0.37 1.07e-12 Body mass index; LIHC cis rs7116495 0.609 rs2845860 chr11:71716661 C/T cg10381502 chr11:71823885 C11orf51 -1.06 -9.3 -0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs17345786 0.906 rs72946021 chr3:101250008 T/G cg12386194 chr3:101231763 SENP7 0.61 8.96 0.44 2.1e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg05368731 chr17:41323189 NBR1 0.72 12.37 0.56 2.77e-29 Menopause (age at onset); LIHC cis rs2455601 0.786 rs11042127 chr11:8947586 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.47 -6.46 -0.33 3.56e-10 Schizophrenia; LIHC trans rs75804782 0.521 rs72993044 chr2:239397949 C/T cg01134436 chr17:81009848 B3GNTL1 0.82 6.89 0.35 2.67e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs12478296 1.000 rs113129906 chr2:243004253 C/T cg06360820 chr2:242988706 NA -0.95 -12.58 -0.56 4.19e-30 Obesity-related traits; LIHC cis rs9549367 0.789 rs6577035 chr13:113879997 G/A cg18105134 chr13:113819100 PROZ -0.67 -11.62 -0.53 1.52e-26 Platelet distribution width; LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg18306943 chr3:40428807 ENTPD3 -0.4 -7.21 -0.36 3.61e-12 Renal cell carcinoma; LIHC cis rs12291225 0.535 rs10832248 chr11:14413087 G/A cg19336497 chr11:14380999 RRAS2 -0.55 -10.34 -0.49 5.52e-22 Sense of smell; LIHC trans rs3960554 0.808 rs9801125 chr7:75792451 C/T cg19862616 chr7:65841803 NCRNA00174 0.6 8.24 0.41 3.81e-15 Eotaxin levels; LIHC cis rs9303401 0.592 rs66583824 chr17:56639853 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs9325144 0.602 rs11169100 chr12:39077861 G/T cg26384229 chr12:38710491 ALG10B -0.43 -6.03 -0.31 4.34e-9 Morning vs. evening chronotype; LIHC cis rs4407350 0.721 rs3827402 chr22:44890651 T/C cg11695653 chr22:44894386 LDOC1L -0.38 -6.45 -0.33 3.88e-10 Intelligence (multi-trait analysis); LIHC cis rs861020 1.000 rs7555285 chr1:209970355 C/G cg05527609 chr1:210001259 C1orf107 -0.8 -11.1 -0.51 1.2e-24 Orofacial clefts; LIHC cis rs4148883 0.651 rs4147547 chr4:100127311 G/T cg12011299 chr4:100065546 ADH4 0.35 6.93 0.35 2.14e-11 Alcohol dependence; LIHC cis rs769267 0.965 rs1469712 chr19:19528821 C/A cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.06 0.4 1.29e-14 Tonsillectomy; LIHC cis rs12188164 0.543 rs2434695 chr5:464177 C/G cg08916839 chr5:415575 AHRR 0.28 6.13 0.31 2.36e-9 Cystic fibrosis severity; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg21548813 chr6:291882 DUSP22 -0.59 -8.43 -0.41 1e-15 Menopause (age at onset); LIHC cis rs9733 0.650 rs11204680 chr1:150587140 T/G cg17724175 chr1:150552817 MCL1 -0.38 -7.69 -0.38 1.62e-13 Tonsillectomy; LIHC cis rs826838 1.000 rs11183469 chr12:38752311 G/A cg13010199 chr12:38710504 ALG10B 0.64 7.62 0.38 2.59e-13 Heart rate; LIHC cis rs7937682 0.632 rs11603779 chr11:111781047 A/C cg09085632 chr11:111637200 PPP2R1B 0.92 13.39 0.59 3.72e-33 Primary sclerosing cholangitis; LIHC cis rs1997103 0.954 rs1917769 chr7:55392325 T/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.39e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9457247 0.967 rs2149083 chr6:167370971 G/C cg12798992 chr6:167411361 FGFR1OP -0.61 -9.79 -0.47 4.11e-20 Crohn's disease; LIHC cis rs6831352 0.918 rs17218073 chr4:100055739 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs9522267 0.535 rs9515454 chr13:112236885 A/G cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs5770917 1.000 rs762676 chr22:51017794 A/G cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.42 -6.12 -0.31 2.57e-9 Narcolepsy; LIHC cis rs4927850 1.000 rs4927704 chr3:195738228 C/T cg12923728 chr3:195709715 SDHAP1 -0.74 -9.86 -0.47 2.43e-20 Pancreatic cancer; LIHC cis rs7757419 1.000 rs7773328 chr6:34435162 A/T cg17518776 chr6:34434842 PACSIN1 -0.28 -5.84 -0.3 1.23e-8 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals; LIHC cis rs7572733 0.534 rs1435570 chr2:198731371 T/C cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs11229555 0.645 rs12797488 chr11:58174653 A/T cg15696309 chr11:58395628 NA -0.64 -7.45 -0.37 7.56e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6762477 0.748 rs11711407 chr3:50225029 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.52 -8.23 -0.41 4.01e-15 Menarche (age at onset); LIHC cis rs3796619 0.503 rs1466216 chr4:1071907 C/T cg27284194 chr4:1044797 NA -0.76 -14.33 -0.61 8.03e-37 Recombination rate (males); LIHC cis rs2281845 0.507 rs1536127 chr1:201086894 C/A cg06714761 chr1:201096289 NA 0.35 5.96 0.31 6.19e-9 Permanent tooth development; LIHC cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg02359409 chr6:42947317 PEX6 -0.48 -6.76 -0.34 6.06e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2625529 0.824 rs12916694 chr15:72298140 C/T cg16672083 chr15:72433130 SENP8 -0.3 -5.78 -0.3 1.73e-8 Red blood cell count; LIHC cis rs1538970 0.924 rs11211108 chr1:45891152 C/T cg24296786 chr1:45957014 TESK2 -0.5 -7.21 -0.36 3.53e-12 Platelet count; LIHC cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg21294424 chr19:58662284 ZNF329 0.94 7.38 0.37 1.23e-12 Cholesterol, total; LIHC cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg24250549 chr1:154909240 PMVK 0.69 11.0 0.51 2.63e-24 Prostate cancer; LIHC cis rs17376456 0.825 rs13156202 chr5:93157721 C/T cg25358565 chr5:93447407 FAM172A -1.03 -9.42 -0.45 6.78e-19 Diabetic retinopathy; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg14528756 chr2:176862893 KIAA1715 -0.28 -6.14 -0.32 2.31e-9 Calcium levels; LIHC cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 7.01 0.35 1.25e-11 Bipolar disorder; LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg00809820 chr17:80708513 TBCD;FN3K 0.4 7.01 0.35 1.3e-11 Glycated hemoglobin levels; LIHC cis rs7044106 0.791 rs3904196 chr9:123480369 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.91 0.39 3.59e-14 Hip circumference adjusted for BMI; LIHC cis rs1144333 0.655 rs11162053 chr1:76470267 A/C cg22875332 chr1:76189707 ACADM 0.4 6.26 0.32 1.14e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs918629 0.567 rs17085266 chr5:95247634 A/C cg10483112 chr5:95245456 ELL2 -0.38 -7.13 -0.36 5.87e-12 IgG glycosylation; LIHC cis rs11958404 0.932 rs72816579 chr5:157431877 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20994686 chr17:71306668 CDC42EP4 0.47 6.36 0.33 6.35e-10 Lung function (FEV1/FVC); LIHC cis rs11098499 0.863 rs7678400 chr4:120461957 G/A cg09307838 chr4:120376055 NA 0.76 11.6 0.53 1.88e-26 Corneal astigmatism; LIHC cis rs9325144 0.671 rs7306605 chr12:38730471 C/T cg26384229 chr12:38710491 ALG10B 0.56 7.82 0.39 6.52e-14 Morning vs. evening chronotype; LIHC cis rs4423214 1.000 rs2282621 chr11:71183474 C/T cg24826892 chr11:71159390 DHCR7 0.47 6.17 0.32 1.91e-9 Vitamin D levels; LIHC cis rs539514 0.591 rs1323710 chr13:76297887 A/G cg04757411 chr13:76259545 LMO7 -0.43 -7.26 -0.37 2.62e-12 Type 1 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18278596 chr14:105915860 MTA1 -0.4 -6.05 -0.31 3.86e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08856378 chr17:560590 VPS53 0.54 6.68 0.34 9.75e-11 Systolic blood pressure; LIHC cis rs11864453 0.928 rs3213420 chr16:72042433 C/T cg16558253 chr16:72132732 DHX38 -0.41 -5.91 -0.3 8.31e-9 Fibrinogen levels; LIHC cis rs4665809 1.000 rs3910272 chr2:26287842 T/A cg04944784 chr2:26401820 FAM59B -0.68 -8.47 -0.42 7.14e-16 Gut microbiome composition (summer); LIHC trans rs9956878 0.555 rs8085188 chr18:73544676 A/G cg14875093 chr19:38398164 WDR87;SIPA1L3 0.38 6.2 0.32 1.6e-9 Obesity-related traits; LIHC cis rs34779708 0.931 rs7099036 chr10:35349574 C/T cg03585969 chr10:35415529 CREM 0.85 12.96 0.57 1.62e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg07092213 chr7:1199455 ZFAND2A -0.41 -6.01 -0.31 4.86e-9 Longevity;Endometriosis; LIHC cis rs35146811 0.844 rs10281368 chr7:99655897 A/G cg13334819 chr7:99746414 C7orf59 -0.57 -8.14 -0.4 7.5e-15 Coronary artery disease; LIHC cis rs477692 0.967 rs496692 chr10:131429100 C/T cg05714579 chr10:131428358 MGMT 0.45 7.35 0.37 1.44e-12 Response to temozolomide; LIHC cis rs12744310 1.000 rs1343775 chr1:41757993 A/G cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg14671364 chr1:107599128 PRMT6 0.5 7.21 0.36 3.73e-12 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7212590 0.748 rs62081818 chr17:57890629 C/T cg10252138 chr17:58120427 NA -0.62 -6.11 -0.31 2.66e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs7264396 0.563 rs73902913 chr20:34432784 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -7.87 -0.39 4.69e-14 Total cholesterol levels; LIHC cis rs3824867 0.920 rs7948705 chr11:47447955 C/G cg20307385 chr11:47447363 PSMC3 -0.58 -7.89 -0.39 4.24e-14 Mean corpuscular hemoglobin; LIHC cis rs910316 1.000 rs11623413 chr14:75588824 C/T cg11812906 chr14:75593930 NEK9 -0.74 -14.44 -0.62 3.01e-37 Height; LIHC cis rs796364 0.756 rs2949006 chr2:200715388 T/G cg23649088 chr2:200775458 C2orf69 0.52 6.13 0.31 2.45e-9 Schizophrenia; LIHC trans rs1005277 0.505 rs10827836 chr10:38215441 A/G cg23533926 chr12:111358616 MYL2 0.33 6.42 0.33 4.5e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7264396 0.635 rs6060685 chr20:34512023 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -10.15 -0.48 2.54e-21 Total cholesterol levels; LIHC cis rs5769765 0.837 rs8142737 chr22:50291889 T/C cg26441486 chr22:50317300 CRELD2 0.36 6.4 0.33 4.99e-10 Schizophrenia; LIHC cis rs10791097 0.694 rs7107595 chr11:130758556 C/T cg22079354 chr11:130786696 SNX19 0.43 6.14 0.31 2.34e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12478296 1.000 rs12478296 chr2:243048760 A/G cg06360820 chr2:242988706 NA 0.79 11.21 0.52 4.9e-25 Obesity-related traits; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg18279126 chr7:2041391 MAD1L1 0.37 6.17 0.32 1.95e-9 Bipolar disorder and schizophrenia; LIHC cis rs11583043 0.918 rs11582211 chr1:101416871 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.82 0.43 5.79e-17 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9322817 0.540 rs2034823 chr6:105219573 A/T cg02098413 chr6:105308735 HACE1 -0.42 -7.55 -0.38 4.01e-13 Thyroid stimulating hormone; LIHC cis rs11628318 0.853 rs4906226 chr14:103027359 C/T cg23461800 chr14:103021989 NA -0.5 -7.15 -0.36 5.28e-12 Platelet count; LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.69 -0.34 9.38e-11 Total body bone mineral density; LIHC cis rs2723064 0.516 rs2901749 chr2:65292570 G/T cg05010058 chr2:65284262 CEP68 0.37 5.96 0.31 6.13e-9 Atrial fibrillation; LIHC cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg22105103 chr4:187893119 NA 0.34 8.74 0.43 1.09e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs3096299 0.967 rs28575874 chr16:89469890 C/T cg08392591 chr16:89556376 ANKRD11 0.42 6.34 0.32 7.28e-10 Multiple myeloma (IgH translocation); LIHC cis rs6788895 1.000 rs73010967 chr3:150498056 T/C cg09723797 chr3:150481914 SIAH2 0.85 11.79 0.54 3.65e-27 Breast cancer; LIHC trans rs2073499 0.935 rs28365992 chr3:50340996 T/C cg21659725 chr3:3221576 CRBN 0.6 6.47 0.33 3.48e-10 Schizophrenia; LIHC cis rs4788570 0.615 rs889568 chr16:71772399 T/C cg06353428 chr16:71660113 MARVELD3 1.39 14.99 0.63 2.11e-39 Intelligence (multi-trait analysis); LIHC cis rs798766 0.868 rs4507432 chr4:1748200 A/G cg21231739 chr4:1642635 FAM53A -0.37 -5.95 -0.31 6.69e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs6977660 0.714 rs10155949 chr7:19834747 T/C cg07541023 chr7:19748670 TWISTNB 0.39 5.76 0.3 1.88e-8 Thyroid stimulating hormone; LIHC cis rs1570884 0.516 rs9316463 chr13:50176844 G/A cg08779649 chr13:50194554 NA 0.35 6.27 0.32 1.12e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC trans rs4843747 0.671 rs72818576 chr16:88111019 C/G cg26811252 chr16:29126840 RRN3P2 0.42 6.85 0.35 3.45e-11 Menopause (age at onset); LIHC cis rs9814567 1.000 rs9835204 chr3:134261342 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs950169 0.920 rs12915390 chr15:84792069 T/C cg17507749 chr15:85114479 UBE2QP1 0.76 7.75 0.39 1.04e-13 Schizophrenia; LIHC cis rs7940866 0.817 rs961491 chr11:130866090 G/T cg12179176 chr11:130786555 SNX19 0.53 7.73 0.39 1.22e-13 Schizophrenia; LIHC cis rs8084351 0.577 rs4270245 chr18:50621050 A/G cg24270629 chr18:50823537 DCC 0.44 6.76 0.34 5.88e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2455601 0.786 rs3763913 chr11:8951230 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -6.29 -0.32 9.81e-10 Schizophrenia; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg07677032 chr17:61819896 STRADA 0.44 6.5 0.33 2.88e-10 Prudent dietary pattern; LIHC cis rs6964587 1.000 rs9690208 chr7:91735613 T/A cg17063962 chr7:91808500 NA 1.01 19.34 0.72 8.03e-57 Breast cancer; LIHC cis rs908922 0.676 rs945788 chr1:152512762 A/G cg20991723 chr1:152506922 NA 0.49 8.85 0.43 4.81e-17 Hair morphology; LIHC cis rs7131987 0.903 rs2194520 chr12:29423712 C/T cg05697976 chr12:29376483 FAR2 0.3 5.93 0.31 7.62e-9 QT interval; LIHC cis rs1882538 0.564 rs10488164 chr7:133106199 A/G cg10665199 chr7:133106180 EXOC4 0.52 8.65 0.42 2.02e-16 Intelligence (multi-trait analysis); LIHC cis rs7582720 1.000 rs77268589 chr2:203751981 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs34779708 0.931 rs7099593 chr10:35366878 A/C cg03585969 chr10:35415529 CREM 0.85 12.9 0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs8058578 0.832 rs7500719 chr16:30840877 C/T cg02466173 chr16:30829666 NA -0.47 -7.35 -0.37 1.49e-12 Multiple myeloma; LIHC cis rs3736485 0.966 rs10519312 chr15:51912971 A/G cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.56e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg06466757 chr4:1255808 NA 0.3 5.77 0.3 1.8e-8 Obesity-related traits; LIHC cis rs7208859 0.623 rs28433704 chr17:29084285 G/C cg13385521 chr17:29058706 SUZ12P 0.83 8.21 0.41 4.55e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600806 0.888 rs4603158 chr1:109879549 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.2 -0.32 1.61e-9 Intelligence (multi-trait analysis); LIHC cis rs9929218 1.000 rs7200690 chr16:68778457 C/T cg01231543 chr16:68741748 NA 0.39 6.13 0.31 2.4e-9 Colorectal cancer; LIHC cis rs4713118 0.869 rs6456802 chr6:27698355 A/G cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs9902453 0.765 rs2729447 chr17:28099002 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs7917772 0.503 rs1409310 chr10:104282265 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7903847 0.620 rs10882903 chr10:99115584 A/T cg20016023 chr10:99160130 RRP12 -0.4 -6.28 -0.32 1.02e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7589728 1.000 rs6722069 chr2:88533151 C/T cg04511125 chr2:88470314 THNSL2 0.76 7.04 0.36 1.03e-11 Plasma clusterin levels; LIHC cis rs55665837 0.701 rs10766188 chr11:14660826 T/C cg25251204 chr11:14927456 NA 0.42 5.76 0.3 1.92e-8 Vitamin D levels; LIHC cis rs637571 0.522 rs3016868 chr11:65764383 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.98 0.31 5.56e-9 Eosinophil percentage of white cells; LIHC cis rs7412746 0.611 rs1889741 chr1:150869045 T/C cg18016565 chr1:150552671 MCL1 0.49 9.43 0.45 6.57e-19 Melanoma; LIHC cis rs9467711 0.606 rs4634439 chr6:26598004 C/T cg09904177 chr6:26538194 HMGN4 0.51 5.92 0.3 7.88e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs11098499 0.691 rs10010355 chr4:120261043 A/G cg09307838 chr4:120376055 NA 0.62 9.89 0.47 1.93e-20 Corneal astigmatism; LIHC cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg17971929 chr21:40555470 PSMG1 0.8 9.65 0.46 1.16e-19 Cognitive function; LIHC cis rs10896135 0.526 rs1987169 chr11:66448044 A/G cg24851651 chr11:66362959 CCS -0.38 -5.98 -0.31 5.56e-9 Bipolar disorder; LIHC cis rs7447593 0.666 rs12659266 chr5:176807197 C/T cg16006841 chr5:176797999 RGS14 0.79 11.54 0.53 3.12e-26 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs1799949 0.965 rs7212284 chr17:41205941 A/G cg05368731 chr17:41323189 NBR1 0.69 11.56 0.53 2.49e-26 Menopause (age at onset); LIHC cis rs1707322 0.686 rs2050376 chr1:46078630 C/T cg06784218 chr1:46089804 CCDC17 0.43 7.73 0.39 1.23e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7100689 0.753 rs1361458 chr10:82090339 A/T cg00277334 chr10:82204260 NA -0.55 -6.87 -0.35 3.02e-11 Post bronchodilator FEV1; LIHC cis rs875971 0.660 rs28698552 chr7:66005018 A/G cg00343986 chr7:65444356 GUSB 0.4 5.99 0.31 5.42e-9 Aortic root size; LIHC cis rs2991971 0.934 rs11580609 chr1:45975856 C/G cg15605315 chr1:45957053 TESK2 0.49 6.72 0.34 7.44e-11 High light scatter reticulocyte count; LIHC cis rs7131987 0.650 rs7954871 chr12:29459732 G/A cg12903224 chr12:29470962 FAR2 -0.39 -6.34 -0.32 7.44e-10 QT interval; LIHC cis rs16958440 0.867 rs2117373 chr18:44671834 C/T cg17192377 chr18:44677553 HDHD2 0.54 6.21 0.32 1.51e-9 Sitting height ratio; LIHC trans rs617791 0.508 rs1047464 chr11:65769456 A/T cg17712092 chr4:129076599 LARP1B -0.56 -6.86 -0.35 3.22e-11 Breast cancer; LIHC cis rs769267 0.930 rs4808203 chr19:19568659 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.65 0.38 2.09e-13 Tonsillectomy; LIHC cis rs17286411 0.750 rs35619990 chr16:71949266 C/T cg03805757 chr16:71968109 PKD1L3 0.42 5.82 0.3 1.35e-8 Blood protein levels; LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg03721293 chr16:90014378 DEF8 0.41 6.89 0.35 2.62e-11 Skin colour saturation; LIHC cis rs7613875 0.600 rs2624832 chr3:50030858 C/T cg05623727 chr3:50126028 RBM5 0.34 5.86 0.3 1.07e-8 Body mass index; LIHC cis rs6952808 0.862 rs4721135 chr7:1912222 A/G cg20295408 chr7:1910781 MAD1L1 -0.44 -6.4 -0.33 5.08e-10 Bipolar disorder and schizophrenia; LIHC cis rs4845459 0.967 rs6700290 chr1:152592978 T/A cg18116418 chr1:152553244 LCE3D -0.31 -5.74 -0.3 2.14e-8 Psoriasis; LIHC cis rs12477438 0.765 rs1453564 chr2:99564428 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.26 -0.41 3.18e-15 Chronic sinus infection; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg07677032 chr17:61819896 STRADA 0.43 6.19 0.32 1.75e-9 Prudent dietary pattern; LIHC cis rs36051895 0.589 rs6476950 chr9:5218416 A/T cg02405213 chr9:5042618 JAK2 -0.66 -10.46 -0.49 2.15e-22 Pediatric autoimmune diseases; LIHC cis rs4906332 1.000 rs17617307 chr14:103904965 C/G cg26031613 chr14:104095156 KLC1 -0.41 -5.78 -0.3 1.66e-8 Coronary artery disease; LIHC trans rs654384 0.898 rs11766511 chr7:4173613 A/G cg26675336 chr15:86133334 AKAP13 0.29 6.18 0.32 1.8e-9 Positive affect; LIHC cis rs3741404 0.825 rs11604782 chr11:63946650 G/A cg04317338 chr11:64019027 PLCB3 0.52 7.11 0.36 6.98e-12 Platelet count; LIHC cis rs17376456 0.877 rs12374470 chr5:93481046 A/G cg25358565 chr5:93447407 FAM172A 1.12 10.28 0.49 8.95e-22 Diabetic retinopathy; LIHC cis rs950776 0.593 rs481134 chr15:78877563 C/T cg06917634 chr15:78832804 PSMA4 0.7 9.57 0.46 2.22e-19 Sudden cardiac arrest; LIHC cis rs4407350 1.000 rs4407350 chr22:44922275 G/A cg11695653 chr22:44894386 LDOC1L -0.38 -6.16 -0.32 2.07e-9 Intelligence (multi-trait analysis); LIHC cis rs9322817 0.691 rs2168394 chr6:105259152 C/T cg02098413 chr6:105308735 HACE1 -0.43 -8.06 -0.4 1.28e-14 Thyroid stimulating hormone; LIHC cis rs12497850 0.897 rs7373778 chr3:48836392 C/G cg20833759 chr3:49053208 WDR6;DALRD3 0.39 5.72 0.3 2.28e-8 Parkinson's disease; LIHC cis rs11711311 0.736 rs13320940 chr3:113400954 G/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.33 5.93 0.31 7.59e-9 IgG glycosylation; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg15089892 chr3:101568188 NFKBIZ 0.51 6.81 0.35 4.32e-11 Myopia (pathological); LIHC cis rs425277 0.606 rs16824792 chr1:2039521 G/T cg04315214 chr1:2043799 PRKCZ 0.36 5.86 0.3 1.11e-8 Height; LIHC cis rs244293 0.657 rs4829 chr17:53039315 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.13 -0.31 2.47e-9 Menarche (age at onset); LIHC cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.98 -0.31 5.68e-9 Colorectal cancer; LIHC cis rs9303401 0.614 rs62084384 chr17:57126842 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.26 0.55 7.01e-29 Cognitive test performance; LIHC cis rs34779708 0.931 rs11593858 chr10:35381373 G/A cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10431058 0.930 rs11212297 chr11:107475371 T/C cg18204760 chr11:107461044 ELMOD1;LOC643923 0.41 6.44 0.33 4.1e-10 Common traits (Other); LIHC cis rs600626 0.529 rs11236525 chr11:75467545 C/G cg24262691 chr11:75473276 NA 0.43 6.49 0.33 3.06e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs72627123 0.867 rs73301479 chr14:74467757 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.63 0.42 2.42e-16 Morning vs. evening chronotype; LIHC cis rs4819052 0.807 rs28715237 chr21:46673768 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.48 0.53 4.87e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8049603 1.000 rs4968046 chr16:23078389 C/T cg16484020 chr16:23217411 SCNN1G -0.25 -5.71 -0.3 2.44e-8 Multiple sclerosis; LIHC cis rs13108904 0.901 rs13112706 chr4:1303682 G/T cg00684032 chr4:1343700 KIAA1530 0.54 7.8 0.39 7.76e-14 Obesity-related traits; LIHC cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg07308232 chr7:1071921 C7orf50 -0.45 -7.21 -0.36 3.55e-12 Longevity;Endometriosis; LIHC cis rs1008375 1.000 rs6849704 chr4:17652031 G/C cg04450456 chr4:17643702 FAM184B 0.34 5.74 0.3 2.05e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7582720 1.000 rs75166090 chr2:203692760 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7512552 0.809 rs696618 chr1:150376139 T/G cg15654264 chr1:150340011 RPRD2 0.69 11.25 0.52 3.29e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2153535 0.580 rs6938071 chr6:8464845 A/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg08499158 chr17:42289980 UBTF -0.5 -8.13 -0.4 7.94e-15 Total body bone mineral density; LIHC cis rs34779708 0.966 rs17500582 chr10:35498788 T/A cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.5e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs249954 0.512 rs249856 chr16:23658976 G/A cg01460202 chr16:23706506 ERN2 0.35 5.75 0.3 1.97e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10779751 1.000 rs2300094 chr1:11266044 C/T cg08854313 chr1:11322531 MTOR 0.86 15.52 0.64 1.73e-41 Body mass index; LIHC cis rs1506636 1.000 rs2215554 chr7:123347063 A/C cg03229431 chr7:123269106 ASB15 -0.52 -10.45 -0.49 2.3e-22 Plateletcrit;Platelet count; LIHC cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg03517284 chr6:25882590 NA -0.64 -8.97 -0.44 1.95e-17 Blood metabolite levels; LIHC trans rs2727020 0.553 rs10839295 chr11:49527345 A/C cg18944383 chr4:111397179 ENPEP 0.25 6.16 0.32 2.02e-9 Coronary artery disease; LIHC cis rs9640161 0.789 rs1464753 chr7:150021350 G/C cg10018233 chr7:150070692 REPIN1 0.57 9.68 0.46 9.89e-20 Blood protein levels;Circulating chemerin levels; LIHC cis rs13190036 0.792 rs6874206 chr5:176650971 G/T cg06532880 chr5:176731545 PRELID1;RAB24 0.43 5.86 0.3 1.09e-8 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs1862618 0.671 rs2591957 chr5:56243146 A/T cg24531977 chr5:56204891 C5orf35 0.52 7.63 0.38 2.37e-13 Initial pursuit acceleration; LIHC cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg02931644 chr1:25747376 RHCE 0.35 7.67 0.38 1.78e-13 Erythrocyte sedimentation rate; LIHC cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg05590025 chr7:65112418 INTS4L2 -0.59 -6.58 -0.34 1.81e-10 Diabetic kidney disease; LIHC cis rs317689 0.718 rs315122 chr12:69771073 G/T cg14784868 chr12:69753453 YEATS4 0.68 10.27 0.49 9.42e-22 Response to diuretic therapy; LIHC cis rs763121 0.925 rs1043312 chr22:39131727 T/G cg14440974 chr22:39074834 NA -0.33 -5.79 -0.3 1.58e-8 Menopause (age at onset); LIHC cis rs6831352 0.918 rs2602894 chr4:100045647 A/G cg12011299 chr4:100065546 ADH4 0.61 10.36 0.49 4.77e-22 Alcohol dependence; LIHC cis rs10256972 0.758 rs9801444 chr7:1080444 A/C cg16145915 chr7:1198662 ZFAND2A 0.34 7.96 0.4 2.48e-14 Longevity;Endometriosis; LIHC cis rs7945718 0.621 rs10831895 chr11:12683327 T/C cg25843174 chr11:12811716 TEAD1 0.33 7.78 0.39 8.58e-14 Educational attainment (years of education); LIHC cis rs679087 1.000 rs436124 chr12:29916839 C/T cg14258853 chr12:29935411 TMTC1 0.49 7.64 0.38 2.14e-13 Schizophrenia; LIHC cis rs116095464 0.614 rs62344292 chr5:244630 G/A cg22857025 chr5:266934 NA -1.46 -17.49 -0.69 2.16e-49 Breast cancer; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg16132339 chr22:24313637 DDTL;DDT 0.73 14.5 0.62 1.78e-37 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg03806693 chr22:41940476 POLR3H -0.9 -10.5 -0.49 1.52e-22 Vitiligo; LIHC trans rs10506458 1.000 rs12580997 chr12:63433420 G/A cg22491629 chr6:157744540 C6orf35 -0.59 -10.39 -0.49 3.84e-22 Hemostatic factors and hematological phenotypes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15457276 chr19:4832024 TICAM1 0.4 6.08 0.31 3.22e-9 Cognitive function; LIHC cis rs3617 0.573 rs62253582 chr3:52928333 G/A cg11645453 chr3:52864694 ITIH4 -0.22 -5.77 -0.3 1.78e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg05896524 chr21:47604654 C21orf56 0.49 7.37 0.37 1.29e-12 Testicular germ cell tumor; LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg00280220 chr17:61926910 NA 0.41 6.5 0.33 2.79e-10 Prudent dietary pattern; LIHC cis rs1198430 0.568 rs1119439 chr1:23828904 A/T cg13183780 chr1:23809682 ASAP3 -0.59 -7.82 -0.39 6.8e-14 Total cholesterol levels; LIHC trans rs12310956 0.532 rs7979535 chr12:33947450 A/C cg26384229 chr12:38710491 ALG10B -0.49 -6.97 -0.35 1.6e-11 Morning vs. evening chronotype; LIHC cis rs7904368 0.951 rs7074647 chr10:16855455 T/C cg23933602 chr10:16859644 RSU1 0.6 5.99 0.31 5.39e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs7208859 0.623 rs56325146 chr17:29151024 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.12 0.4 8.32e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 0.862 rs6959268 chr7:65812966 G/A cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.07e-40 Aortic root size; LIHC trans rs4906332 0.966 rs17679729 chr14:103924312 A/G cg17675199 chr6:35436792 RPL10A 0.34 6.61 0.34 1.44e-10 Coronary artery disease; LIHC cis rs7264396 0.790 rs2425125 chr20:34330954 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.69 11.93 0.54 1.17e-27 Total cholesterol levels; LIHC cis rs35883536 1.000 rs17403857 chr1:101105216 A/C cg14515779 chr1:101123966 NA -0.66 -13.12 -0.58 3.93e-32 Monocyte count; LIHC trans rs116095464 0.558 rs10036253 chr5:238519 A/C cg00938859 chr5:1591904 SDHAP3 0.58 7.11 0.36 7.03e-12 Breast cancer; LIHC cis rs8141529 0.711 rs5752797 chr22:29179998 C/T cg15103426 chr22:29168792 CCDC117 0.5 7.5 0.38 5.51e-13 Lymphocyte counts; LIHC cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg22663859 chr13:21900854 NA 0.46 7.32 0.37 1.79e-12 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs4665809 1.000 rs11126375 chr2:26344787 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs77741769 0.571 rs1542859 chr12:121336766 A/G cg02419362 chr12:121203948 SPPL3 0.35 6.0 0.31 4.97e-9 Mean corpuscular volume; LIHC cis rs2997447 0.706 rs61776574 chr1:26429492 C/T cg19633962 chr1:26362018 EXTL1 -0.71 -6.2 -0.32 1.61e-9 QRS complex (12-leadsum); LIHC cis rs9902453 0.817 rs17226179 chr17:28168573 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.31 0.55 4.57e-29 Coffee consumption (cups per day); LIHC cis rs8067545 0.750 rs11871651 chr17:19997425 T/C cg13482628 chr17:19912719 NA 0.53 9.01 0.44 1.51e-17 Schizophrenia; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12830829 chr14:51707081 TMX1 -0.35 -6.15 -0.32 2.18e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs950776 0.518 rs3813572 chr15:78832588 T/C cg06917634 chr15:78832804 PSMA4 0.94 14.45 0.62 2.7e-37 Sudden cardiac arrest; LIHC cis rs919433 0.647 rs2045242 chr2:198507649 G/A cg10820045 chr2:198174542 NA 0.46 7.25 0.37 2.8e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs526821 0.553 rs519637 chr11:55295935 A/T cg04317927 chr11:55418816 OR4S2 0.47 8.95 0.44 2.33e-17 Pediatric bone mineral density (spine); LIHC cis rs7131987 0.650 rs3782509 chr12:29453778 G/A cg14222432 chr12:29376421 FAR2 0.35 6.72 0.34 7.42e-11 QT interval; LIHC cis rs17102423 0.594 rs1124752 chr14:65567515 G/T cg16583315 chr14:65563665 MAX -0.4 -8.2 -0.41 5.07e-15 Obesity-related traits; LIHC cis rs6089584 0.706 rs6089625 chr20:60620622 T/C cg23262073 chr20:60523788 NA -0.28 -6.02 -0.31 4.44e-9 Body mass index; LIHC cis rs933688 1.000 rs889213 chr5:90682151 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.6 0.67 8.33e-46 Smoking behavior; LIHC cis rs7552404 0.727 rs5745427 chr1:76332637 C/A cg03433033 chr1:76189801 ACADM -0.54 -6.87 -0.35 3.06e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9303401 0.527 rs2116450 chr17:56745561 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.93 12.04 0.55 4.45e-28 Cognitive test performance; LIHC cis rs3758785 0.623 rs13447720 chr11:94165326 T/C cg21580213 chr11:94231278 ANKRD49 -0.38 -6.43 -0.33 4.38e-10 Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy); LIHC cis rs757081 0.671 rs214070 chr11:17305317 T/A cg15432903 chr11:17409602 KCNJ11 -0.45 -5.96 -0.31 6.28e-9 Systolic blood pressure; LIHC cis rs62380364 0.565 rs40504 chr5:88011139 G/C cg22951263 chr5:87985283 NA -0.37 -6.41 -0.33 4.82e-10 Intelligence (multi-trait analysis); LIHC cis rs2980439 0.870 rs2945230 chr8:8109936 A/G cg15556689 chr8:8085844 FLJ10661 0.43 6.36 0.33 6.3e-10 Neuroticism; LIHC cis rs11098499 0.863 rs13140409 chr4:120503460 A/G cg09307838 chr4:120376055 NA 0.75 11.88 0.54 1.71e-27 Corneal astigmatism; LIHC cis rs12893668 0.703 rs12894729 chr14:104035292 G/A cg24130564 chr14:104152367 KLC1 -0.55 -8.9 -0.43 3.42e-17 Reticulocyte count; LIHC cis rs7223966 0.961 rs17631394 chr17:61646000 A/G cg05941027 chr17:61774174 LIMD2 -0.3 -6.04 -0.31 4.01e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg13047869 chr3:10149882 C3orf24 0.54 6.41 0.33 4.82e-10 Alzheimer's disease; LIHC trans rs875971 0.520 rs12666485 chr7:65625122 T/C cg26939375 chr7:64535504 NA 0.41 6.47 0.33 3.36e-10 Aortic root size; LIHC cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg08822215 chr16:89438651 ANKRD11 -0.44 -6.83 -0.35 3.88e-11 Multiple myeloma (IgH translocation); LIHC cis rs801193 0.569 rs2659907 chr7:66164032 G/A cg18876405 chr7:65276391 NA 0.32 5.75 0.3 1.93e-8 Aortic root size; LIHC cis rs2073300 0.609 rs6132615 chr20:23413200 T/C cg12062639 chr20:23401060 NAPB 1.02 12.94 0.57 1.96e-31 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11122272 0.735 rs2749707 chr1:231527316 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.26e-23 Hemoglobin concentration; LIHC cis rs7089973 0.525 rs11196945 chr10:116600424 G/A cg03647239 chr10:116582469 FAM160B1 0.45 6.67 0.34 1.02e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs769267 0.929 rs2905431 chr19:19482882 G/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.01 -0.31 4.78e-9 Tonsillectomy; LIHC cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg13409248 chr3:40428643 ENTPD3 0.42 6.93 0.35 2.04e-11 Renal cell carcinoma; LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg03721293 chr16:90014378 DEF8 0.39 6.59 0.34 1.63e-10 Skin colour saturation; LIHC cis rs7772486 0.654 rs1011597 chr6:146075672 A/C cg23711669 chr6:146136114 FBXO30 -0.7 -12.73 -0.57 1.14e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs12464559 0.649 rs11894672 chr2:152657055 C/T cg01189475 chr2:152685088 ARL5A 0.64 7.48 0.38 6.16e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7249142 0.562 rs1050544 chr19:19287901 A/G cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.36 -6.06 -0.31 3.57e-9 IgG glycosylation; LIHC cis rs10744422 1.000 rs897385 chr12:123341297 A/G cg22842854 chr12:123319900 HIP1R -0.74 -9.83 -0.47 2.99e-20 Schizophrenia; LIHC cis rs2997447 0.723 rs2259849 chr1:26474251 A/T cg19633962 chr1:26362018 EXTL1 -0.54 -6.37 -0.33 6.17e-10 QRS complex (12-leadsum); LIHC cis rs2302777 0.507 rs9889716 chr17:38108298 A/G cg17467752 chr17:38218738 THRA 0.4 6.05 0.31 3.79e-9 Multiple myeloma (hyperdiploidy); LIHC cis rs1144333 0.655 rs76992868 chr1:76418916 G/A cg10523679 chr1:76189770 ACADM 0.45 6.08 0.31 3.19e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg02359409 chr6:42947317 PEX6 -0.45 -6.0 -0.31 5.07e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1355223 1.000 rs35365094 chr11:34767790 A/C cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.35 -0.32 6.83e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1577917 1.000 rs11759855 chr6:86610841 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.76 -0.5 1.82e-23 Response to antipsychotic treatment; LIHC cis rs1538970 0.816 rs3790583 chr1:45956828 C/G cg05343316 chr1:45956843 TESK2 0.63 9.45 0.46 5.47e-19 Platelet count; LIHC cis rs9486719 1.000 rs12191653 chr6:96903898 T/C cg06623918 chr6:96969491 KIAA0776 -0.72 -7.13 -0.36 5.89e-12 Migraine;Coronary artery disease; LIHC trans rs2243480 1.000 rs11538349 chr7:65421871 C/T cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs7131987 0.874 rs10843366 chr12:29407903 T/C cg21522988 chr12:29376872 FAR2 0.28 6.42 0.33 4.61e-10 QT interval; LIHC cis rs4803468 1.000 rs10409485 chr19:41920765 C/T cg09537434 chr19:41945824 ATP5SL 1.03 21.81 0.76 1.01e-66 Height; LIHC cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg09455208 chr3:40491958 NA 0.33 6.48 0.33 3.25e-10 Renal cell carcinoma; LIHC cis rs9443189 0.950 rs276698 chr6:76473071 T/C cg01950844 chr6:76311363 SENP6 0.49 5.86 0.3 1.11e-8 Prostate cancer; LIHC cis rs4450131 0.522 rs4465331 chr10:126400357 C/T cg20435097 chr10:126320824 FAM53B 0.65 11.83 0.54 2.71e-27 White blood cell count (basophil); LIHC cis rs1448094 0.512 rs1900701 chr12:86236231 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.31 0.32 8.83e-10 Major depressive disorder; LIHC cis rs17094448 0.557 rs117276277 chr14:74497463 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.99 0.44 1.76e-17 Blood protein levels; LIHC cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.78 0.69 1.56e-50 Gut microbiome composition (summer); LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.81e-9 Developmental language disorder (linguistic errors); LIHC cis rs7085104 0.632 rs7096475 chr10:104609676 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.93 -0.43 2.74e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs1371867 0.846 rs1613453 chr8:101244215 G/T cg06002616 chr8:101225028 SPAG1 0.34 5.72 0.3 2.36e-8 Atrioventricular conduction; LIHC cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg16497277 chr3:49208875 KLHDC8B -0.48 -6.0 -0.31 5.01e-9 Menarche (age at onset); LIHC trans rs1945213 0.659 rs2086558 chr11:55844453 T/G cg03929089 chr4:120376271 NA 0.53 6.8 0.35 4.54e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs35306767 0.903 rs11812523 chr10:915638 C/T cg20503657 chr10:835505 NA 1.07 12.48 0.56 9.98e-30 Eosinophil percentage of granulocytes; LIHC cis rs11608355 0.515 rs61941631 chr12:109935475 C/T cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs2354432 0.607 rs7511989 chr1:146720160 A/G cg25205988 chr1:146714368 CHD1L -0.89 -10.59 -0.5 7.24e-23 Mitochondrial DNA levels; LIHC cis rs736408 0.522 rs998909 chr3:52805093 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.42 0.45 7.19e-19 Bipolar disorder; LIHC cis rs9790314 0.747 rs1599386 chr3:160856314 C/T cg03342759 chr3:160939853 NMD3 0.67 8.25 0.41 3.55e-15 Morning vs. evening chronotype; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.99 0.63 2.09e-39 Prudent dietary pattern; LIHC cis rs16828019 0.852 rs71648536 chr1:41632008 T/A cg20697417 chr1:41786797 NA 0.34 6.57 0.33 1.92e-10 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07609388 chr8:89341103 MMP16 0.45 6.94 0.35 1.95e-11 Pancreatic cancer; LIHC cis rs7129220 0.512 rs1867138 chr11:10228728 A/G cg01453529 chr11:10209919 SBF2 -0.36 -5.87 -0.3 1.05e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs4423214 1.000 rs1044482 chr11:71155171 C/T cg24826892 chr11:71159390 DHCR7 0.52 6.85 0.35 3.5e-11 Vitamin D levels; LIHC cis rs561341 0.843 rs879944 chr17:30242803 A/G cg12193833 chr17:30244370 NA -0.51 -5.9 -0.3 8.77e-9 Hip circumference adjusted for BMI; LIHC cis rs16858210 0.657 rs73177515 chr3:183566825 T/A cg25686905 chr3:183603175 PARL -0.48 -8.4 -0.41 1.21e-15 Menopause (age at onset); LIHC cis rs2243480 1.000 rs778729 chr7:65824419 T/C cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.85 -0.39 5.42e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs9303280 0.617 rs4795406 chr17:38100134 G/C cg17467752 chr17:38218738 THRA 0.37 6.02 0.31 4.53e-9 Self-reported allergy; LIHC cis rs3768617 0.510 rs10797843 chr1:183081995 A/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.72 0.5 2.59e-23 Fuchs's corneal dystrophy; LIHC cis rs7224737 1.000 rs7225608 chr17:40298326 G/A cg20291162 chr17:40259547 DHX58 -0.41 -6.74 -0.34 6.92e-11 Fibrinogen levels; LIHC cis rs2067615 0.579 rs12312782 chr12:107135647 G/A cg15890332 chr12:107067104 RFX4 0.27 6.31 0.32 8.77e-10 Heart rate; LIHC cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg03517284 chr6:25882590 NA -0.56 -8.21 -0.41 4.58e-15 Blood metabolite levels; LIHC cis rs597539 0.652 rs646586 chr11:68681653 C/T cg04772025 chr11:68637568 NA -0.45 -5.89 -0.3 9.47e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs17685 0.672 rs6465011 chr7:75811297 T/C cg19862616 chr7:65841803 NCRNA00174 0.9 18.37 0.7 6.22e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7940866 1.000 rs7940866 chr11:130817579 A/T cg12179176 chr11:130786555 SNX19 -0.48 -6.76 -0.34 5.85e-11 Schizophrenia; LIHC cis rs12997796 0.556 rs7558827 chr2:86923178 A/G cg25203885 chr2:87302643 LOC285074 -0.62 -5.8 -0.3 1.55e-8 Schizophrenia; LIHC cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg26939375 chr7:64535504 NA 0.48 7.22 0.36 3.46e-12 Calcium levels; LIHC cis rs611744 0.967 rs635624 chr8:109197799 G/C cg18478394 chr8:109455254 TTC35 0.4 6.94 0.35 1.93e-11 Dupuytren's disease; LIHC cis rs225245 0.817 rs225299 chr17:33922742 T/C cg05299278 chr17:33885742 SLFN14 0.21 5.74 0.3 2.06e-8 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs72781680 1.000 rs56205282 chr2:24221317 C/T cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs4319547 0.737 rs4758646 chr12:122946507 G/A cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.32 -0.41 2.16e-15 Body mass index; LIHC cis rs7100689 0.646 rs7089003 chr10:82124155 T/C cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs1005277 0.579 rs176880 chr10:38401417 C/G cg25427524 chr10:38739819 LOC399744 0.65 12.44 0.56 1.43e-29 Extrinsic epigenetic age acceleration; LIHC cis rs11190604 1.000 rs11190613 chr10:102313997 C/T cg07080220 chr10:102295463 HIF1AN -0.46 -6.55 -0.33 2.14e-10 Palmitoleic acid (16:1n-7) levels; LIHC trans rs11165623 0.564 rs9887897 chr1:96996671 T/C cg10631902 chr5:14652156 NA -0.29 -6.77 -0.34 5.62e-11 Hip circumference;Waist circumference; LIHC cis rs12893668 0.603 rs61637848 chr14:104096031 C/T cg24130564 chr14:104152367 KLC1 -0.56 -9.58 -0.46 2.02e-19 Reticulocyte count; LIHC cis rs56235845 0.694 rs11949401 chr5:176765989 A/G cg16006841 chr5:176797999 RGS14 0.55 7.56 0.38 3.71e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs8083850 0.635 rs9950970 chr18:50863808 T/C cg24270629 chr18:50823537 DCC -0.56 -8.58 -0.42 3.47e-16 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.559 rs6921504 chr6:88058972 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.35 0.37 1.48e-12 Monocyte percentage of white cells; LIHC cis rs6546550 0.901 rs6546553 chr2:70111711 C/A cg02498382 chr2:70120550 SNRNP27 -0.41 -6.98 -0.35 1.57e-11 Prevalent atrial fibrillation; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs4423214 0.840 rs1629220 chr11:71174553 C/T cg05163923 chr11:71159392 DHCR7 -0.6 -7.93 -0.39 3.16e-14 Vitamin D levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05611805 chr7:120498369 TSPAN12 0.38 6.22 0.32 1.46e-9 Cognitive function; LIHC cis rs11031096 0.628 rs10835735 chr11:4211865 G/C cg18678763 chr11:4115507 RRM1 -0.4 -5.76 -0.3 1.85e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs595982 0.527 rs73061656 chr19:49372355 G/A cg15549821 chr19:49342101 PLEKHA4 -0.69 -6.46 -0.33 3.5e-10 Red cell distribution width; LIHC cis rs9837602 0.529 rs1087198 chr3:99524381 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.83 -0.3 1.26e-8 Breast cancer; LIHC trans rs6500602 0.927 rs7200817 chr16:4480598 G/C cg05791018 chr13:19965014 NA -0.28 -6.39 -0.33 5.49e-10 Schizophrenia; LIHC cis rs4689642 0.756 rs4689091 chr4:7226892 G/A cg21353189 chr4:7228343 SORCS2 0.37 6.14 0.32 2.28e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7520050 0.966 rs6668284 chr1:46354510 G/A cg03146154 chr1:46216737 IPP -0.39 -6.46 -0.33 3.65e-10 Red blood cell count;Reticulocyte count; LIHC cis rs4243830 0.850 rs10864612 chr1:6593830 C/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.94 -12.02 -0.54 5.51e-28 Body mass index; LIHC cis rs9381040 0.674 rs3747742 chr6:41162518 C/T cg03526776 chr6:41159608 TREML2 -0.34 -6.15 -0.32 2.22e-9 Alzheimer's disease (late onset); LIHC cis rs12497850 1.000 rs12493578 chr3:48730116 C/T cg07636037 chr3:49044803 WDR6 -0.79 -12.71 -0.57 1.47e-30 Parkinson's disease; LIHC cis rs10883723 0.579 rs1967815 chr10:104287051 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.61 6.23 0.32 1.35e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs11628318 0.660 rs12887323 chr14:103083322 T/C cg12046867 chr14:103022105 NA -0.47 -6.79 -0.34 4.94e-11 Platelet count; LIHC cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg05368731 chr17:41323189 NBR1 0.71 12.09 0.55 2.96e-28 Menopause (age at onset); LIHC cis rs2303745 0.589 rs1864115 chr19:17393327 G/C cg02221750 chr19:17393354 ANKLE1 -0.41 -5.9 -0.3 8.53e-9 Systemic lupus erythematosus; LIHC cis rs798554 0.836 rs798526 chr7:2775542 G/C cg04166393 chr7:2884313 GNA12 0.44 6.17 0.32 1.96e-9 Height; LIHC cis rs35883536 0.588 rs114540631 chr1:101101249 A/G cg14515779 chr1:101123966 NA -0.6 -11.37 -0.52 1.21e-25 Monocyte count; LIHC cis rs600806 0.815 rs10858088 chr1:109923586 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.659 rs34556735 chr17:56694447 A/C cg10487724 chr17:56770010 TEX14;RAD51C 1.02 14.03 0.6 1.23e-35 Cognitive test performance; LIHC cis rs9837602 0.507 rs793455 chr3:99526135 C/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.4 -5.71 -0.3 2.41e-8 Breast cancer; LIHC cis rs1865721 1.000 rs3813080 chr18:73186227 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.78 -0.39 8.81e-14 Intelligence; LIHC cis rs4423214 1.000 rs12785878 chr11:71167449 G/T cg24826892 chr11:71159390 DHCR7 0.47 6.11 0.31 2.68e-9 Vitamin D levels; LIHC cis rs950169 1.000 rs1848093 chr15:84755527 G/C cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs2153535 0.580 rs3938660 chr6:8443335 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg24531977 chr5:56204891 C5orf35 -0.66 -9.43 -0.45 6.36e-19 Initial pursuit acceleration; LIHC cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg16405210 chr4:1374714 KIAA1530 -0.46 -7.0 -0.35 1.36e-11 Obesity-related traits; LIHC cis rs10089 1.000 rs2898096 chr5:127433214 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.74 0.34 6.54e-11 Ileal carcinoids; LIHC cis rs60871478 0.635 rs4311567 chr7:792295 T/C cg11064039 chr7:766100 PRKAR1B;HEATR2 0.51 5.73 0.3 2.25e-8 Cerebrospinal P-tau181p levels; LIHC cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg21724239 chr8:58056113 NA 0.63 7.42 0.37 9.21e-13 Developmental language disorder (linguistic errors); LIHC cis rs875971 1.000 rs12698523 chr7:65968113 C/G cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.56e-9 Aortic root size; LIHC cis rs11098499 0.754 rs12509621 chr4:120249660 T/C cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.14e-25 Corneal astigmatism; LIHC cis rs11958404 0.932 rs56204919 chr5:157431084 C/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg24633967 chr5:134195255 C5orf24 -0.3 -6.39 -0.33 5.33e-10 Calcium levels; LIHC cis rs1163251 0.869 rs629735 chr1:120206932 G/T cg19096424 chr1:120255104 PHGDH -0.6 -7.45 -0.37 7.5e-13 Blood metabolite levels; LIHC cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg04944784 chr2:26401820 FAM59B 0.72 9.21 0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs11098699 0.718 rs13116874 chr4:124212211 T/C cg09941581 chr4:124220074 SPATA5 0.33 6.6 0.34 1.57e-10 Mosquito bite size; LIHC cis rs4555082 0.718 rs2816619 chr14:105732551 G/C cg06808227 chr14:105710500 BRF1 -0.49 -6.05 -0.31 3.79e-9 Mean platelet volume;Platelet distribution width; LIHC trans rs4650994 1.000 rs12138561 chr1:178518784 G/T cg05059571 chr16:84539110 KIAA1609 -0.39 -6.49 -0.33 2.94e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7772486 0.846 rs2892453 chr6:146377717 C/A cg05347473 chr6:146136440 FBXO30 0.34 5.76 0.3 1.9e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2997447 0.846 rs3008235 chr1:26408409 T/C cg19633962 chr1:26362018 EXTL1 -0.53 -6.2 -0.32 1.59e-9 QRS complex (12-leadsum); LIHC cis rs9790314 0.628 rs1599381 chr3:160867680 G/A cg03342759 chr3:160939853 NMD3 -0.76 -11.83 -0.54 2.75e-27 Morning vs. evening chronotype; LIHC cis rs919433 0.889 rs787995 chr2:198216853 T/G cg10820045 chr2:198174542 NA 0.53 8.93 0.43 2.67e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9611565 0.512 rs1983576 chr22:42166486 G/A cg03806693 chr22:41940476 POLR3H 0.98 10.31 0.49 7.06e-22 Vitiligo; LIHC cis rs908922 0.627 rs11590073 chr1:152500810 C/T cg20991723 chr1:152506922 NA 0.57 10.06 0.48 4.84e-21 Hair morphology; LIHC cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg00149659 chr3:10157352 C3orf10 0.63 6.55 0.33 2.14e-10 Alzheimer's disease; LIHC cis rs644799 0.544 rs1150360 chr11:95512060 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.64 9.3 0.45 1.77e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs903552 1.000 rs12908079 chr15:102003820 C/A cg19295451 chr15:102010161 PCSK6 -0.45 -6.44 -0.33 4.11e-10 Diabetic kidney disease; LIHC trans rs11088226 0.581 rs2833856 chr21:33877691 A/G cg09050820 chr6:167586206 TCP10L2 -0.48 -7.35 -0.37 1.52e-12 Gastritis; LIHC cis rs13126513 0.708 rs883028 chr4:100451375 A/G cg05468953 chr4:100565104 NA 0.32 6.35 0.32 7e-10 Metabolite levels (MHPG); LIHC cis rs10876993 0.928 rs774890 chr12:58068388 C/T cg18357645 chr12:58087776 OS9 0.52 8.53 0.42 4.81e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs9303401 0.527 rs2116450 chr17:56745561 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.89 11.16 0.52 7.3e-25 Cognitive test performance; LIHC cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6665290 0.904 rs3738729 chr1:227191227 C/T cg10327440 chr1:227177885 CDC42BPA -1.18 -25.62 -0.81 1.41e-81 Myeloid white cell count; LIHC cis rs6963495 0.818 rs6957192 chr7:105150255 A/C cg19920283 chr7:105172520 RINT1 -0.68 -6.52 -0.33 2.48e-10 Bipolar disorder (body mass index interaction); LIHC cis rs1046896 0.519 rs9900369 chr17:80829807 G/A cg02711726 chr17:80685570 FN3KRP -0.44 -8.16 -0.4 6.4e-15 Glycated hemoglobin levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13027571 chr2:219081765 ARPC2 -0.62 -7.12 -0.36 6.59e-12 Systolic blood pressure; LIHC cis rs35146811 0.622 rs6946204 chr7:99589125 T/C cg22906224 chr7:99728672 NA 0.48 6.43 0.33 4.24e-10 Coronary artery disease; LIHC cis rs7131987 0.718 rs7976961 chr12:29463088 C/T cg14222432 chr12:29376421 FAR2 0.35 6.84 0.35 3.66e-11 QT interval; LIHC cis rs9660992 0.573 rs4400674 chr1:205218425 A/C cg21545522 chr1:205238299 TMCC2 -0.37 -7.1 -0.36 7.49e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs67311347 1.000 rs28434528 chr3:40484893 A/G cg18306943 chr3:40428807 ENTPD3 0.34 6.06 0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs1552244 0.882 rs3755782 chr3:10029305 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.66 -10.32 -0.49 6.31e-22 Alzheimer's disease; LIHC cis rs7647973 0.925 rs4955423 chr3:49220448 G/A cg07636037 chr3:49044803 WDR6 0.51 6.49 0.33 3.08e-10 Menarche (age at onset); LIHC cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.84 -11.88 -0.54 1.68e-27 Alzheimer's disease; LIHC cis rs7301016 0.846 rs17732182 chr12:63026131 C/T cg11441379 chr12:63026424 NA 0.61 6.26 0.32 1.15e-9 IgG glycosylation; LIHC cis rs6732160 0.684 rs2043095 chr2:73407442 T/C cg24220031 chr2:73402428 NA -0.27 -5.77 -0.3 1.76e-8 Intelligence (multi-trait analysis); LIHC cis rs7726839 0.561 rs72703050 chr5:582917 A/C cg09021430 chr5:549028 NA -0.4 -8.48 -0.42 6.68e-16 Obesity-related traits; LIHC cis rs5769707 0.967 rs2051626 chr22:50008973 G/A cg07959070 chr22:50026188 C22orf34 -0.32 -8.42 -0.41 1.03e-15 Monocyte count;Monocyte percentage of white cells; LIHC trans rs8073060 0.660 rs34184070 chr17:34003810 A/G cg19694781 chr19:47549865 TMEM160 -1.25 -13.18 -0.58 2.36e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6570726 0.905 rs1355146 chr6:145781741 A/C cg23711669 chr6:146136114 FBXO30 -0.45 -7.63 -0.38 2.4e-13 Lobe attachment (rater-scored or self-reported); LIHC trans rs7618501 1.000 rs11130219 chr3:49752427 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.641 rs4819283 chr21:45083011 T/A cg01579765 chr21:45077557 HSF2BP -0.34 -6.23 -0.32 1.4e-9 Mean corpuscular volume; LIHC cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg06238570 chr21:40685208 BRWD1 0.6 7.11 0.36 6.92e-12 Cognitive function; LIHC cis rs743757 0.878 rs9867588 chr3:50526880 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.48 7.24 0.36 3.07e-12 Diastolic blood pressure; LIHC cis rs240764 0.658 rs7746947 chr6:101188708 G/A cg12253828 chr6:101329408 ASCC3 -0.39 -5.95 -0.31 6.78e-9 Neuroticism; LIHC cis rs7572733 0.534 rs4550664 chr2:198691405 C/T cg10820045 chr2:198174542 NA 0.46 7.01 0.35 1.3e-11 Dermatomyositis; LIHC cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs918629 0.724 rs55841351 chr5:95278019 A/G cg10483112 chr5:95245456 ELL2 -0.35 -6.02 -0.31 4.47e-9 IgG glycosylation; LIHC cis rs2235642 0.701 rs2281230 chr16:1601767 T/C cg03034668 chr16:1723424 CRAMP1L -0.36 -6.1 -0.31 2.88e-9 Coronary artery disease; LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 7.99 0.4 2.15e-14 Height; LIHC cis rs9517320 0.515 rs4771307 chr13:99221879 A/G cg07423050 chr13:99094983 FARP1 -0.47 -7.88 -0.39 4.39e-14 Longevity; LIHC cis rs7551222 0.789 rs2290855 chr1:204515863 C/T cg20240347 chr1:204465584 NA -0.35 -7.48 -0.37 6.4e-13 Schizophrenia; LIHC cis rs950169 0.840 rs62029595 chr15:84955301 C/T cg12863693 chr15:85201151 NMB 0.41 5.73 0.3 2.25e-8 Schizophrenia; LIHC cis rs8005677 1.000 rs8014936 chr14:23375145 A/G cg07971674 chr14:23388846 RBM23 -0.41 -5.89 -0.3 9.2e-9 Cognitive ability (multi-trait analysis); LIHC cis rs9911578 0.967 rs6503890 chr17:57064167 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.76 -0.43 9.46e-17 Intelligence (multi-trait analysis); LIHC cis rs2455799 0.613 rs13071730 chr3:15891035 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.96e-13 Mean platelet volume; LIHC cis rs9660992 0.710 rs1172111 chr1:205232980 C/T cg21545522 chr1:205238299 TMCC2 0.38 7.4 0.37 1.1e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg10150615 chr22:24372951 LOC391322 -0.49 -7.27 -0.37 2.5e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg15664640 chr17:80829946 TBCD 0.38 5.99 0.31 5.25e-9 Glycated hemoglobin levels; LIHC cis rs597539 0.690 rs497149 chr11:68626639 A/T cg04772025 chr11:68637568 NA 0.45 6.1 0.31 2.91e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2016586 0.802 rs5999974 chr22:36115897 C/A cg26342177 chr22:36113512 APOL5 -0.39 -6.57 -0.33 1.82e-10 Body mass index; LIHC cis rs72720396 0.694 rs6689362 chr1:91203251 T/A cg13456504 chr1:91191583 NA -0.5 -7.38 -0.37 1.19e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs1506636 0.854 rs6466879 chr7:123276197 G/A cg03229431 chr7:123269106 ASB15 -0.61 -12.74 -0.57 1.08e-30 Plateletcrit;Platelet count; LIHC cis rs6089829 0.925 rs11086152 chr20:61664656 T/C cg08564027 chr20:61660810 NA 0.4 7.68 0.38 1.68e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs919433 0.680 rs67580728 chr2:198431258 C/T cg03934865 chr2:198174659 NA 0.53 8.07 0.4 1.18e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs763121 0.853 rs2284073 chr22:39105948 T/C cg21395723 chr22:39101663 GTPBP1 0.37 6.17 0.32 1.92e-9 Menopause (age at onset); LIHC cis rs3741404 0.537 rs1123251 chr11:63917601 G/T cg18225595 chr11:63971243 STIP1 -0.46 -6.06 -0.31 3.59e-9 Platelet count; LIHC cis rs2224391 0.911 rs6925249 chr6:5262510 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs908922 0.651 rs1337341 chr1:152508259 A/C cg20991723 chr1:152506922 NA 0.54 9.36 0.45 1.13e-18 Hair morphology; LIHC cis rs13108904 0.517 rs13128825 chr4:1334007 G/A cg00684032 chr4:1343700 KIAA1530 0.58 8.54 0.42 4.36e-16 Obesity-related traits; LIHC cis rs950169 0.580 rs17598114 chr15:85171317 C/T cg12863693 chr15:85201151 NMB 0.49 7.11 0.36 6.72e-12 Schizophrenia; LIHC cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg18357526 chr6:26021779 HIST1H4A 0.42 6.28 0.32 1.03e-9 Height; LIHC cis rs2404602 0.647 rs35710279 chr15:77082234 T/A cg03037974 chr15:76606532 NA -0.6 -9.96 -0.47 1.13e-20 Blood metabolite levels; LIHC cis rs12095069 1 rs12095069 chr1:76463072 T/C cg22875332 chr1:76189707 ACADM 0.4 6.24 0.32 1.26e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06217312 chr1:150552348 MCL1 -0.44 -6.1 -0.31 2.84e-9 Pancreatic cancer; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg05484376 chr2:27715224 FNDC4 0.37 6.33 0.32 7.68e-10 Total body bone mineral density; LIHC cis rs2073300 1.000 rs17830565 chr20:23444805 G/A cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3820068 0.581 rs16849152 chr1:15921774 A/C cg17385448 chr1:15911702 AGMAT 0.35 6.15 0.32 2.21e-9 Systolic blood pressure; LIHC cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg09222892 chr1:25734099 RHCE -0.47 -8.74 -0.43 1.07e-16 Erythrocyte sedimentation rate; LIHC cis rs7633770 0.735 rs12491236 chr3:46688481 C/T cg11219411 chr3:46661640 NA -0.43 -7.49 -0.38 6.02e-13 Coronary artery disease; LIHC cis rs6964587 0.839 rs11767135 chr7:91551245 T/G cg17063962 chr7:91808500 NA -0.96 -18.04 -0.7 1.31e-51 Breast cancer; LIHC cis rs796364 1.000 rs1704186 chr2:200769539 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.03 0.44 1.32e-17 Schizophrenia; LIHC cis rs2072499 0.966 rs2842857 chr1:156168736 T/C cg06970220 chr1:156163860 SLC25A44 0.48 5.81 0.3 1.42e-8 Testicular germ cell tumor; LIHC cis rs11786130 1.000 rs3815871 chr8:129008578 G/C cg01765152 chr8:129005526 PVT1 -0.3 -6.33 -0.32 7.77e-10 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs17125944 0.572 rs79312783 chr14:53250296 A/T cg00686598 chr14:53173677 PSMC6 1.19 15.39 0.64 5.81e-41 Alzheimer's disease (late onset); LIHC cis rs10751667 1.000 rs10902233 chr11:925510 A/G cg10932868 chr11:921992 NA 0.36 6.61 0.34 1.48e-10 Alzheimer's disease (late onset); LIHC cis rs10789491 0.953 rs1866770 chr1:47182468 G/T cg15501359 chr1:47185051 KIAA0494 0.77 10.87 0.51 7.86e-24 Response to hepatitis C treatment; LIHC cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs17376456 0.569 rs6556834 chr5:93123067 C/T cg25358565 chr5:93447407 FAM172A -0.78 -7.56 -0.38 3.8e-13 Diabetic retinopathy; LIHC cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg25072359 chr17:41440525 NA 0.39 6.07 0.31 3.42e-9 Menopause (age at onset); LIHC cis rs1371867 0.846 rs2919469 chr8:101233896 C/T cg06636551 chr8:101224915 SPAG1 -0.51 -9.53 -0.46 3e-19 Atrioventricular conduction; LIHC cis rs2777491 0.915 rs9302109 chr15:41612180 G/T cg18705301 chr15:41695430 NDUFAF1 -0.55 -8.15 -0.4 7.18e-15 Ulcerative colitis; LIHC cis rs2412488 0.927 rs1021099 chr4:54245775 A/G cg22241045 chr4:54363911 LNX1 -0.4 -6.48 -0.33 3.15e-10 DNA methylation (variation); LIHC cis rs9457247 0.967 rs1794696 chr6:167396174 T/C cg12798992 chr6:167411361 FGFR1OP 0.52 8.03 0.4 1.59e-14 Crohn's disease; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg24209194 chr3:40518798 ZNF619 0.57 8.69 0.43 1.48e-16 Renal cell carcinoma; LIHC cis rs1046896 0.562 rs9912684 chr17:80873067 C/T cg19500275 chr17:80737654 TBCD 0.41 5.78 0.3 1.72e-8 Glycated hemoglobin levels; LIHC cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg22907277 chr7:1156413 C7orf50 -0.51 -7.75 -0.39 1.07e-13 Longevity;Endometriosis; LIHC cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg12463550 chr7:65579703 CRCP 0.67 7.18 0.36 4.48e-12 Diabetic kidney disease; LIHC cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.08 11.63 0.53 1.49e-26 Platelet count; LIHC cis rs919433 0.713 rs2045245 chr2:198485341 A/C cg03934865 chr2:198174659 NA 0.53 7.94 0.39 2.92e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9733 0.791 rs11204693 chr1:150647987 C/T cg13175981 chr1:150552382 MCL1 0.5 7.74 0.39 1.1e-13 Tonsillectomy; LIHC cis rs7605378 0.528 rs281791 chr2:200850402 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.53 -7.11 -0.36 6.85e-12 Osteoporosis; LIHC cis rs6461049 0.800 rs3800913 chr7:2163237 A/G cg14004847 chr7:1930337 MAD1L1 -0.42 -6.19 -0.32 1.73e-9 Schizophrenia; LIHC cis rs2991971 0.967 rs60608374 chr1:46008913 G/A cg15605315 chr1:45957053 TESK2 0.48 6.54 0.33 2.24e-10 High light scatter reticulocyte count; LIHC cis rs6598163 0.564 rs12319878 chr12:132289989 C/T cg13251533 chr12:132286017 NA 0.39 6.52 0.33 2.47e-10 Migraine; LIHC cis rs6089829 0.925 rs2277767 chr20:61666937 G/A cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs2274273 0.870 rs1952087 chr14:55683211 A/C cg01864836 chr14:55583639 NA -0.4 -7.62 -0.38 2.49e-13 Protein biomarker; LIHC cis rs9733 0.596 rs72702585 chr1:150696427 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.2e-9 Tonsillectomy; LIHC cis rs7187994 0.848 rs12933228 chr16:84770691 G/A cg07647771 chr16:84786436 USP10 -0.34 -6.17 -0.32 1.9e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs858239 0.600 rs6960001 chr7:23130876 T/C cg23682824 chr7:23144976 KLHL7 0.45 6.78 0.34 5.17e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04696171 chr16:89787876 C16orf7;ZNF276 0.38 6.15 0.32 2.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7208859 0.623 rs9914242 chr17:29216245 G/T cg14067834 chr17:29058358 SUZ12P 0.6 5.78 0.3 1.72e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg22105103 chr4:187893119 NA 0.35 8.96 0.44 2.08e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg18252515 chr7:66147081 NA -1.27 -16.34 -0.66 9.2e-45 Diabetic kidney disease; LIHC cis rs5758343 1 rs5758343 chr22:41816652 A/T cg06481639 chr22:41940642 POLR3H 0.7 6.85 0.35 3.35e-11 Allergic disease (asthma, hay fever or eczema); LIHC cis rs17685 0.697 rs2302437 chr7:75677016 G/A cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.14 0.31 2.34e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9314323 0.964 rs3808579 chr8:26250682 C/T cg13160058 chr8:26243215 BNIP3L -0.44 -8.11 -0.4 9.27e-15 Red cell distribution width; LIHC cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg13047869 chr3:10149882 C3orf24 0.48 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs1559088 0.501 rs35599132 chr19:33570554 G/A cg27124370 chr19:33622961 WDR88 0.49 6.9 0.35 2.56e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs3809863 0.602 rs6504833 chr17:45396087 A/G cg08085267 chr17:45401833 C17orf57 -0.64 -9.88 -0.47 2.06e-20 Glaucoma (primary open-angle); LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.2 0.55 1.12e-28 Prudent dietary pattern; LIHC cis rs6456156 0.586 rs6909180 chr6:167460537 A/G cg23791538 chr6:167370224 RNASET2 -0.53 -8.42 -0.41 1.04e-15 Primary biliary cholangitis; LIHC cis rs6066825 0.644 rs6066823 chr20:47338768 C/G cg18078177 chr20:47281410 PREX1 0.4 6.49 0.33 2.98e-10 Colorectal cancer; LIHC cis rs600806 0.665 rs1368988 chr1:110012123 A/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.25 -0.32 1.22e-9 Intelligence (multi-trait analysis); LIHC cis rs4700695 0.841 rs36303 chr5:65350374 A/G cg21114390 chr5:65439923 SFRS12 -0.45 -5.71 -0.3 2.43e-8 Facial morphology (factor 19); LIHC cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg08677398 chr8:58056175 NA 0.41 5.99 0.31 5.21e-9 Developmental language disorder (linguistic errors); LIHC cis rs4654899 1.000 rs6683542 chr1:21369610 T/C cg08539965 chr1:21396338 EIF4G3 0.33 5.74 0.3 2.07e-8 Superior frontal gyrus grey matter volume; LIHC cis rs7208859 0.623 rs426434 chr17:28925353 C/T cg14067834 chr17:29058358 SUZ12P 0.64 6.31 0.32 8.84e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs11098499 0.955 rs13114751 chr4:120156617 G/A cg25214090 chr10:38739885 LOC399744 0.54 8.11 0.4 8.92e-15 Corneal astigmatism; LIHC cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg12310025 chr6:25882481 NA -0.63 -7.84 -0.39 5.63e-14 Intelligence (multi-trait analysis); LIHC trans rs9354352 0.784 rs2062327 chr6:66689923 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -9.64 -0.46 1.27e-19 Initial pursuit acceleration in psychotic disorders; LIHC cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg03452623 chr4:187889614 NA -0.31 -7.74 -0.39 1.11e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs12824058 0.831 rs11616174 chr12:130814503 A/G cg24838063 chr12:130822603 PIWIL1 0.66 9.79 0.47 4.16e-20 Menopause (age at onset); LIHC cis rs7116495 0.867 rs609492 chr11:71563123 T/C cg26138937 chr11:71823887 C11orf51 0.63 6.11 0.31 2.64e-9 Severe influenza A (H1N1) infection; LIHC cis rs7572733 0.534 rs700678 chr2:198705820 T/C cg03934865 chr2:198174659 NA 0.46 6.64 0.34 1.2e-10 Dermatomyositis; LIHC cis rs9324022 0.626 rs10873520 chr14:101175967 G/A cg18089426 chr14:101175970 NA 0.57 7.63 0.38 2.41e-13 Plateletcrit; LIHC cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg12310025 chr6:25882481 NA 0.48 6.06 0.31 3.66e-9 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs2486737 chr1:231520523 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs826838 0.904 rs10880981 chr12:38763911 G/A cg13010199 chr12:38710504 ALG10B 0.64 7.62 0.38 2.59e-13 Heart rate; LIHC cis rs4820294 1.000 rs929039 chr22:38071511 T/C cg00142150 chr22:38071001 LGALS1 0.69 11.05 0.51 1.84e-24 Fat distribution (HIV); LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.85 -0.35 3.51e-11 Diastolic blood pressure; LIHC cis rs3096299 0.617 rs2353030 chr16:89405827 C/T cg08822215 chr16:89438651 ANKRD11 0.45 7.41 0.37 1.03e-12 Multiple myeloma (IgH translocation); LIHC cis rs6500602 0.647 rs1684600 chr16:4594671 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.41 -6.12 -0.31 2.5e-9 Schizophrenia; LIHC cis rs3820068 0.655 rs72645823 chr1:15887442 C/T cg17385448 chr1:15911702 AGMAT 0.41 6.8 0.35 4.65e-11 Systolic blood pressure; LIHC cis rs6912958 0.559 rs376633 chr6:88042785 T/C cg08069147 chr6:88032118 GJB7;C6orf162 0.59 11.1 0.51 1.19e-24 Monocyte percentage of white cells; LIHC cis rs10193935 1.000 rs10185742 chr2:42429666 A/G cg27598129 chr2:42591480 NA -0.72 -11.15 -0.52 7.6e-25 Colonoscopy-negative controls vs population controls; LIHC trans rs11098499 0.954 rs13151285 chr4:120314741 C/A cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs2404602 0.716 rs17362383 chr15:76650702 A/G cg03037974 chr15:76606532 NA 0.8 16.38 0.66 6.39e-45 Blood metabolite levels; LIHC cis rs2979489 1.000 rs2979469 chr8:30285091 C/G cg26383811 chr8:30366931 RBPMS 0.62 9.4 0.45 8.03e-19 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs11229555 1.000 rs2298608 chr11:58404467 A/G cg15696309 chr11:58395628 NA 0.73 8.92 0.43 2.91e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 3.15e-30 Menopause (age at onset); LIHC cis rs2153535 0.601 rs1737581 chr6:8539138 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.33 0.41 2.02e-15 Motion sickness; LIHC cis rs875971 0.790 rs10257911 chr7:65743770 A/G cg11764359 chr7:65958608 NA -0.78 -13.44 -0.59 2.29e-33 Aortic root size; LIHC cis rs9486715 0.867 rs4839687 chr6:96951732 C/A cg06623918 chr6:96969491 KIAA0776 0.84 14.88 0.63 5.67e-39 Headache; LIHC cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg04317338 chr11:64019027 PLCB3 0.84 10.53 0.49 1.23e-22 Mean platelet volume; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg12419862 chr22:24373484 LOC391322 -0.73 -10.91 -0.51 5.54e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.08 0.36 8.26e-12 Renal cell carcinoma; LIHC cis rs2708977 0.899 rs12992413 chr2:97277489 A/G cg01950434 chr2:97203154 ARID5A 0.5 7.33 0.37 1.73e-12 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg05590025 chr7:65112418 INTS4L2 -0.58 -6.31 -0.32 8.87e-10 Diabetic kidney disease; LIHC cis rs4407350 0.756 rs135622 chr22:44890658 T/C cg26276947 chr22:44892394 LDOC1L 0.34 6.43 0.33 4.31e-10 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.543 rs4719436 chr7:2141239 G/A cg04267008 chr7:1944627 MAD1L1 -0.53 -8.35 -0.41 1.69e-15 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg00280220 chr17:61926910 NA 0.42 6.74 0.34 6.72e-11 Prudent dietary pattern; LIHC cis rs11098499 0.820 rs28578366 chr4:120536905 A/G cg09307838 chr4:120376055 NA -0.72 -11.15 -0.52 7.92e-25 Corneal astigmatism; LIHC cis rs10771431 1.000 rs11611670 chr12:9385535 C/T cg08997352 chr12:9597637 DDX12 -0.5 -7.27 -0.37 2.41e-12 Breast size; LIHC cis rs60871478 1.000 rs34086011 chr7:805430 C/T cg04727924 chr7:799746 HEATR2 -0.58 -8.61 -0.42 2.7e-16 Cerebrospinal P-tau181p levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17152101 chr1:32509371 KHDRBS1 -0.25 -6.18 -0.32 1.87e-9 Calcium levels; LIHC cis rs1144333 0.655 rs58722308 chr1:76423525 A/G cg10523679 chr1:76189770 ACADM 0.45 6.08 0.31 3.19e-9 Attention function in attention deficit hyperactive disorder; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg25195416 chr21:46696626 POFUT2 0.6 6.54 0.33 2.22e-10 Mean platelet volume; LIHC cis rs2797160 1.000 rs2211418 chr6:125995503 G/A cg05901451 chr6:126070800 HEY2 -0.44 -7.81 -0.39 7.1e-14 Endometrial cancer; LIHC cis rs644799 0.930 rs587123 chr11:95560539 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs600806 0.676 rs573491 chr1:110026891 T/G cg02415029 chr1:110025642 ATXN7L2 0.46 6.05 0.31 3.75e-9 Intelligence (multi-trait analysis); LIHC cis rs7727544 0.636 rs2631365 chr5:131705949 T/C cg07395648 chr5:131743802 NA 0.31 6.54 0.33 2.22e-10 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06714086 chr11:33182787 CSTF3 0.46 6.9 0.35 2.57e-11 Cognitive function; LIHC cis rs9467773 0.587 rs12214031 chr6:26376628 T/C cg09904177 chr6:26538194 HMGN4 -0.38 -6.11 -0.31 2.72e-9 Intelligence (multi-trait analysis); LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg01822624 chr5:32710882 NPR3 -0.43 -6.21 -0.32 1.56e-9 Body mass index; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15216925 chr5:179921655 CNOT6 0.45 6.82 0.35 4.22e-11 Calcium levels; LIHC cis rs600806 0.778 rs2043059 chr1:109991009 C/A cg23091122 chr1:110024289 SYPL2 -0.52 -6.93 -0.35 2.04e-11 Intelligence (multi-trait analysis); LIHC cis rs870825 0.932 rs28594349 chr4:185574415 G/A cg04058563 chr4:185651563 MLF1IP 0.75 5.9 0.3 8.88e-9 Blood protein levels; LIHC cis rs9291683 0.588 rs17246745 chr4:9994583 T/C cg11266682 chr4:10021025 SLC2A9 0.33 6.75 0.34 6.52e-11 Bone mineral density; LIHC cis rs10870270 1.000 rs7199 chr10:133769848 C/G cg26149184 chr10:133730230 NA 0.47 7.41 0.37 1.03e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9325144 0.532 rs12812406 chr12:38719802 G/A cg26384229 chr12:38710491 ALG10B -0.55 -7.55 -0.38 3.92e-13 Morning vs. evening chronotype; LIHC cis rs6790105 1 rs6790105 chr3:49393409 C/T cg07636037 chr3:49044803 WDR6 0.49 6.02 0.31 4.41e-9 Childhood ear infection; LIHC cis rs12220238 0.915 rs2894235 chr10:76082945 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2455601 0.608 rs59025804 chr11:8870301 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.5 -8.42 -0.41 1.08e-15 Schizophrenia; LIHC cis rs1144333 0.655 rs1146649 chr1:76268803 A/G cg03433033 chr1:76189801 ACADM -0.54 -7.67 -0.38 1.78e-13 Attention function in attention deficit hyperactive disorder; LIHC trans rs11039100 1.000 rs11039100 chr11:5827003 C/T cg11650987 chr12:10280440 CLEC7A -0.4 -6.15 -0.32 2.17e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg07677032 chr17:61819896 STRADA 0.41 5.97 0.31 6.09e-9 Prudent dietary pattern; LIHC cis rs7412746 0.658 rs11582281 chr1:150826831 T/C cg15448220 chr1:150897856 SETDB1 0.39 5.79 0.3 1.63e-8 Melanoma; LIHC cis rs2204008 0.569 rs11495449 chr12:37995753 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC trans rs11039798 0.841 rs10839174 chr11:48931185 G/A cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC cis rs9399135 0.967 rs6902954 chr6:135313994 C/A cg22676075 chr6:135203613 NA 0.39 6.31 0.32 8.89e-10 Red blood cell count; LIHC cis rs17152411 1.000 rs7097282 chr10:126593492 T/C cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.42e-12 Height; LIHC cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 8.96 0.44 2.11e-17 Electroencephalogram traits; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg04871131 chr7:94954202 PON1 -0.36 -6.07 -0.31 3.33e-9 Paraoxonase activity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01634057 chr4:123843788 NUDT6;SPATA5 0.49 6.22 0.32 1.45e-9 Lung function (FEV1/FVC); LIHC cis rs17711722 0.583 rs10085415 chr7:65093568 T/A cg11764359 chr7:65958608 NA -0.63 -8.3 -0.41 2.41e-15 Calcium levels; LIHC cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg16049864 chr8:95962084 TP53INP1 -0.58 -11.0 -0.51 2.62e-24 Type 2 diabetes; LIHC cis rs1401999 0.650 rs3792585 chr3:183646222 A/G cg01324343 chr3:183735012 ABCC5 0.53 8.43 0.41 9.67e-16 Anterior chamber depth; LIHC cis rs208520 0.690 rs4710311 chr6:66823223 C/T cg07460842 chr6:66804631 NA -0.71 -8.32 -0.41 2.17e-15 Exhaled nitric oxide output; LIHC cis rs55665837 0.540 rs10832294 chr11:14747427 C/A cg25251204 chr11:14927456 NA 0.41 5.83 0.3 1.25e-8 Vitamin D levels; LIHC cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg10360323 chr17:41437877 NA 0.39 5.83 0.3 1.27e-8 Menopause (age at onset); LIHC cis rs7772486 0.875 rs6934467 chr6:146410529 G/T cg05347473 chr6:146136440 FBXO30 0.36 5.72 0.3 2.36e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs6489882 0.867 rs6489867 chr12:113363550 C/T cg10175203 chr3:128143634 NA 0.38 6.13 0.31 2.38e-9 Chronic lymphocytic leukemia; LIHC cis rs921968 0.541 rs4674308 chr2:219310483 A/C cg02985541 chr2:219472218 PLCD4 0.44 7.27 0.37 2.42e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs12477438 0.520 rs2632276 chr2:99779655 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.97 0.78 2.82e-71 Chronic sinus infection; LIHC cis rs2404602 0.692 rs12904198 chr15:77146978 G/A cg03037974 chr15:76606532 NA 0.74 14.58 0.62 8.64e-38 Blood metabolite levels; LIHC cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg12310025 chr6:25882481 NA 0.88 11.87 0.54 1.9e-27 Blood metabolite levels; LIHC trans rs1814175 0.904 rs7924371 chr11:49620595 C/T cg03929089 chr4:120376271 NA -0.88 -17.28 -0.68 1.62e-48 Height; LIHC cis rs34779708 0.966 rs4934725 chr10:35398236 T/C cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7715806 0.509 rs34349 chr5:74944868 A/G cg00601450 chr5:74908170 NA -0.73 -9.42 -0.45 7.03e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6738485 0.507 rs66569888 chr2:106886967 G/A cg00318621 chr2:106887213 NA -0.59 -5.92 -0.3 7.99e-9 Pursuit maintenance gain;Pursuit maintenance gain in psychotic disorders; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg14671364 chr1:107599128 PRMT6 -0.53 -7.65 -0.38 2.01e-13 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs74233809 1.000 rs79668541 chr10:104793904 C/T cg03493300 chr10:104813866 CNNM2 0.47 6.17 0.32 1.97e-9 Birth weight; LIHC cis rs7927771 1.000 rs12418852 chr11:47868853 C/G cg20135002 chr11:47629003 NA -0.53 -8.97 -0.44 1.94e-17 Subjective well-being; LIHC cis rs9303401 0.659 rs35103007 chr17:56900738 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.21 0.55 1.02e-28 Cognitive test performance; LIHC cis rs4742903 0.967 rs4743689 chr9:106909300 G/A cg14250997 chr9:106856677 SMC2 0.4 7.1 0.36 7.46e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6442522 1.000 rs6442522 chr3:15440556 C/T cg16303742 chr3:15540471 COLQ 0.42 6.99 0.35 1.48e-11 Uric acid levels; LIHC cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs9300255 0.596 rs4460848 chr12:123677810 A/G cg00376283 chr12:123451042 ABCB9 0.7 10.64 0.5 4.85e-23 Neutrophil percentage of white cells; LIHC trans rs9409565 0.513 rs16912862 chr9:97050005 A/G cg05679027 chr9:99775184 HIATL2 -0.38 -6.52 -0.33 2.52e-10 Colorectal cancer (alcohol consumption interaction); LIHC cis rs5997397 1.000 rs5997397 chr22:29154455 A/G cg02153584 chr22:29168773 CCDC117 0.48 7.14 0.36 5.51e-12 Red cell distribution width; LIHC cis rs10911251 0.527 rs1537520 chr1:183084229 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.47 0.49 2e-22 Colorectal cancer; LIHC cis rs9443189 0.570 rs9343316 chr6:76411800 G/A cg01950844 chr6:76311363 SENP6 0.87 10.9 0.51 6.08e-24 Prostate cancer; LIHC trans rs2727020 0.894 rs10839265 chr11:49369733 C/T cg03929089 chr4:120376271 NA -0.66 -9.86 -0.47 2.31e-20 Coronary artery disease; LIHC cis rs4660306 0.672 rs532639 chr1:46024481 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.51 -5.97 -0.31 5.79e-9 Homocysteine levels; LIHC cis rs1538970 0.924 rs2088100 chr1:45877575 C/T cg05343316 chr1:45956843 TESK2 0.59 8.54 0.42 4.33e-16 Platelet count; LIHC cis rs2153535 0.580 rs7743418 chr6:8438128 A/C cg21535247 chr6:8435926 SLC35B3 0.6 7.82 0.39 6.61e-14 Motion sickness; LIHC cis rs4808199 0.842 rs11085259 chr19:19445856 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.56 8.12 0.4 8.8e-15 Nonalcoholic fatty liver disease; LIHC cis rs1448094 0.580 rs11615323 chr12:86282171 T/C cg02569458 chr12:86230093 RASSF9 0.48 6.43 0.33 4.42e-10 Major depressive disorder; LIHC trans rs66887589 0.774 rs9307477 chr4:120421809 G/A cg25214090 chr10:38739885 LOC399744 0.39 6.51 0.33 2.7e-10 Diastolic blood pressure; LIHC cis rs7103411 0.637 rs6416056 chr11:27646745 A/G cg18117895 chr11:27722066 BDNF 0.44 6.34 0.32 7.12e-10 Menarche (age at onset);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs875971 0.862 rs11773628 chr7:65982631 G/T cg11764359 chr7:65958608 NA -0.85 -15.39 -0.64 5.63e-41 Aortic root size; LIHC cis rs8017423 0.608 rs12589866 chr14:90820977 T/C cg04374321 chr14:90722782 PSMC1 -0.48 -7.08 -0.36 8.41e-12 Mortality in heart failure; LIHC cis rs8067545 0.935 rs7209734 chr17:19988543 C/A cg13482628 chr17:19912719 NA 0.56 9.33 0.45 1.36e-18 Schizophrenia; LIHC cis rs6904897 0.538 rs4639353 chr6:135224328 A/G cg22676075 chr6:135203613 NA -0.6 -10.51 -0.49 1.39e-22 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs11734570 0.581 rs79354477 chr4:38597448 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.54 7.29 0.37 2.14e-12 Inflammatory bowel disease;Crohn's disease; LIHC trans rs208520 0.545 rs6899712 chr6:66749670 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.85 15.39 0.64 5.52e-41 Exhaled nitric oxide output; LIHC cis rs7208859 0.623 rs73269913 chr17:29092183 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.12 0.4 8.8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8064299 0.597 rs9893035 chr17:72783798 A/C cg25054828 chr17:72772726 NAT9;TMEM104 0.73 12.69 0.57 1.62e-30 Monocyte count; LIHC cis rs2242116 0.896 rs724449 chr3:46935681 C/T cg27129171 chr3:47204927 SETD2 0.48 7.67 0.38 1.79e-13 Birth weight; LIHC cis rs7582180 0.675 rs4851313 chr2:101029002 A/G cg14675211 chr2:100938903 LONRF2 -0.46 -7.08 -0.36 8.3e-12 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.597 rs2246132 chr6:146182515 C/G cg05347473 chr6:146136440 FBXO30 0.5 7.7 0.38 1.48e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs4332037 1.000 rs10240470 chr7:1949971 G/T cg23422044 chr7:1970798 MAD1L1 0.57 6.69 0.34 9.33e-11 Bipolar disorder; LIHC cis rs864643 1.000 rs1707988 chr3:39551526 G/A cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs3768617 0.510 rs1547712 chr1:183088013 T/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs526231 0.853 rs1991797 chr5:102622453 G/T cg05225461 chr5:102596755 C5orf30 0.38 5.9 0.3 8.85e-9 Primary biliary cholangitis; LIHC cis rs924607 0.898 rs905193 chr5:635095 T/C cg04221910 chr5:616842 CEP72 0.41 7.33 0.37 1.63e-12 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs59901009 0.863 rs56758314 chr11:10192648 C/T cg01453529 chr11:10209919 SBF2 -0.32 -6.39 -0.33 5.55e-10 Hematocrit;Hemoglobin concentration; LIHC cis rs6500602 0.727 rs8051389 chr16:4570570 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.77 0.39 9.57e-14 Schizophrenia; LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs8067545 0.750 rs62067555 chr17:20001502 T/C cg13482628 chr17:19912719 NA 0.49 7.98 0.4 2.24e-14 Schizophrenia; LIHC cis rs3845702 0.668 rs6759271 chr2:180844303 T/C cg01881094 chr2:180872142 CWC22 -1.13 -10.08 -0.48 4.44e-21 Schizophrenia; LIHC cis rs921968 0.565 rs6436071 chr2:219598041 A/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6582630 0.638 rs61931383 chr12:38513845 G/A cg26384229 chr12:38710491 ALG10B -0.49 -6.83 -0.35 3.86e-11 Drug-induced liver injury (flucloxacillin); LIHC trans rs11148252 0.904 rs9526927 chr13:53051627 C/T cg18335740 chr13:41363409 SLC25A15 0.35 6.12 0.31 2.55e-9 Lewy body disease; LIHC cis rs2404602 0.692 rs4360890 chr15:77173295 G/A cg23625390 chr15:77176239 SCAPER 0.35 5.73 0.3 2.21e-8 Blood metabolite levels; LIHC cis rs12586317 0.586 rs2295103 chr14:35515920 C/G cg05294307 chr14:35346193 BAZ1A -0.5 -7.26 -0.37 2.64e-12 Psoriasis; LIHC cis rs34172651 0.517 rs874484 chr16:24803242 T/C cg00339695 chr16:24857497 SLC5A11 0.73 10.43 0.49 2.65e-22 Intelligence (multi-trait analysis); LIHC cis rs5753618 0.509 rs5753500 chr22:31578879 A/G cg22777020 chr22:31556080 RNF185 -0.55 -6.32 -0.32 8.03e-10 Colorectal cancer; LIHC trans rs208520 0.955 rs12202599 chr6:67001573 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 6.91 0.35 2.36e-11 Exhaled nitric oxide output; LIHC cis rs4073582 0.595 rs708472 chr11:65930990 A/G cg16950941 chr11:66035639 RAB1B 0.55 8.28 0.41 2.73e-15 Gout; LIHC cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg13395646 chr4:1353034 KIAA1530 -0.66 -9.6 -0.46 1.78e-19 Obesity-related traits; LIHC cis rs950169 0.580 rs11630887 chr15:85193015 A/T cg12863693 chr15:85201151 NMB 0.48 6.98 0.35 1.52e-11 Schizophrenia; LIHC cis rs244293 0.965 rs244357 chr17:53193181 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.54 -0.38 4.15e-13 Menarche (age at onset); LIHC cis rs7772486 0.875 rs6913797 chr6:146413758 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.97 0.31 6.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 0.713 rs73073505 chr3:40310693 C/T cg00091569 chr3:40428383 ENTPD3 0.37 6.04 0.31 4.03e-9 Renal cell carcinoma; LIHC trans rs61931739 0.500 rs12809868 chr12:34464905 C/T cg26384229 chr12:38710491 ALG10B 0.76 9.43 0.45 6.65e-19 Morning vs. evening chronotype; LIHC cis rs6088590 1.000 rs11696546 chr20:33452999 C/G cg24642439 chr20:33292090 TP53INP2 0.75 9.98 0.47 9.57e-21 Coronary artery disease; LIHC cis rs8084351 0.599 rs948524 chr18:50677159 T/C cg24270629 chr18:50823537 DCC -0.45 -6.73 -0.34 7.1e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs12477438 0.765 rs6740054 chr2:99576631 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.26 -0.41 3.27e-15 Chronic sinus infection; LIHC cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs67460515 0.563 rs6441362 chr3:160877613 G/A cg17135325 chr3:160939158 NMD3 0.6 8.63 0.42 2.32e-16 Parkinson's disease; LIHC cis rs6065325 0.514 rs4812512 chr20:40094515 C/A cg06610464 chr20:40243608 CHD6 0.38 6.16 0.32 2.07e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg05185784 chr16:90016020 DEF8 -0.44 -5.96 -0.31 6.27e-9 Skin colour saturation; LIHC cis rs477692 1.000 rs503660 chr10:131418999 A/G cg19680672 chr10:131412579 MGMT -0.43 -6.61 -0.34 1.44e-10 Response to temozolomide; LIHC cis rs9303280 0.773 rs11078925 chr17:38025208 T/C cg11212589 chr17:38028394 ZPBP2 0.35 6.97 0.35 1.65e-11 Self-reported allergy; LIHC cis rs16828019 0.852 rs12406620 chr1:41512664 A/T cg03962019 chr1:41807865 NA 0.49 7.03 0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs62229266 0.626 rs2835268 chr21:37449136 C/G cg12218747 chr21:37451666 NA -0.43 -6.96 -0.35 1.8e-11 Mitral valve prolapse; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19531713 chr17:41277059 BRCA1;NBR2 0.46 6.67 0.34 1.03e-10 Pancreatic cancer; LIHC cis rs17401966 0.931 rs11121545 chr1:10411211 A/G cg19773385 chr1:10388646 KIF1B -0.4 -6.87 -0.35 3.01e-11 Hepatocellular carcinoma; LIHC cis rs3741404 0.825 rs7111753 chr11:63942189 A/G cg04317338 chr11:64019027 PLCB3 0.49 6.73 0.34 7.06e-11 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11601666 chr17:8286754 RPL26 0.43 6.08 0.31 3.16e-9 Lung function (FEV1/FVC); LIHC cis rs12594515 1.000 rs56220882 chr15:45997075 C/G cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs61677309 1.000 rs59450866 chr11:118167707 C/T cg06090739 chr11:118230722 UBE4A 0.35 6.44 0.33 4.14e-10 Lung cancer in ever smokers; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg12565055 chr22:29076175 TTC28 -0.41 -6.39 -0.33 5.33e-10 Systolic blood pressure; LIHC trans rs62103177 0.564 rs7228971 chr18:77738025 C/T cg05926928 chr17:57297772 GDPD1 -0.71 -7.72 -0.39 1.28e-13 Opioid sensitivity; LIHC cis rs13064411 0.696 rs869342 chr3:113226330 C/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs853679 0.517 rs9295758 chr6:28120663 C/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs72781680 0.611 rs72783625 chr2:24315540 C/T cg06627628 chr2:24431161 ITSN2 -0.64 -7.48 -0.37 6.51e-13 Lymphocyte counts; LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg09417038 chr21:47716443 C21orf57 0.49 7.58 0.38 3.31e-13 Testicular germ cell tumor; LIHC cis rs1448094 0.512 rs12314318 chr12:86249238 T/C cg02569458 chr12:86230093 RASSF9 0.46 6.19 0.32 1.76e-9 Major depressive disorder; LIHC cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg01206211 chr2:36825736 FEZ2 0.52 9.0 0.44 1.58e-17 Height; LIHC cis rs17125944 0.615 rs7146915 chr14:53316039 C/T cg00686598 chr14:53173677 PSMC6 -0.76 -9.19 -0.45 3.83e-18 Alzheimer's disease (late onset); LIHC cis rs739401 0.572 rs384490 chr11:3078885 A/C cg20651018 chr11:3035856 CARS -0.36 -6.18 -0.32 1.81e-9 Longevity; LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg04234412 chr22:24373322 LOC391322 -0.72 -11.13 -0.52 9.29e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg11890956 chr21:40555474 PSMG1 1.03 14.11 0.61 6.12e-36 Cognitive function; LIHC cis rs6691722 0.506 rs11587667 chr1:24715435 C/G cg18323236 chr1:24743029 NIPAL3 0.41 7.96 0.4 2.54e-14 Response to interferon beta in multiple sclerosis; LIHC cis rs311392 0.902 rs681000 chr8:55094043 C/T cg20636351 chr8:55087400 NA -0.37 -7.58 -0.38 3.26e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs2404602 0.692 rs4383105 chr15:77055510 T/C cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.9e-38 Blood metabolite levels; LIHC cis rs9457247 1.000 rs385113 chr6:167403971 A/G cg12798992 chr6:167411361 FGFR1OP 0.6 10.02 0.48 6.67e-21 Crohn's disease; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg08949621 chr15:42265044 EHD4 -0.43 -6.04 -0.31 3.99e-9 Triglycerides; LIHC cis rs8072100 0.676 rs9905308 chr17:45409386 T/A cg25173405 chr17:45401733 C17orf57 -0.57 -8.48 -0.42 6.85e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2806561 0.780 rs12117752 chr1:23360223 T/C cg19743168 chr1:23544995 NA -0.36 -6.64 -0.34 1.26e-10 Height; LIHC cis rs12478296 1.000 rs55742408 chr2:243041077 G/A cg18898632 chr2:242989856 NA -0.57 -7.68 -0.38 1.66e-13 Obesity-related traits; LIHC cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg11644478 chr21:40555479 PSMG1 0.85 10.78 0.5 1.6e-23 Cognitive function; LIHC cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg26566898 chr11:117069891 TAGLN 0.48 7.46 0.37 7.01e-13 Blood protein levels; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02046226 chr10:121410475 BAG3 0.47 6.19 0.32 1.74e-9 Hepatitis; LIHC cis rs6665290 0.904 rs1045285 chr1:227179054 G/A cg10327440 chr1:227177885 CDC42BPA -1.18 -26.56 -0.82 4.07e-85 Myeloid white cell count; LIHC cis rs7264396 0.580 rs6119655 chr20:34412049 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -9.9 -0.47 1.81e-20 Total cholesterol levels; LIHC cis rs896854 1.000 rs896854 chr8:95960511 T/C cg16049864 chr8:95962084 TP53INP1 -0.67 -13.21 -0.58 1.83e-32 Type 2 diabetes; LIHC cis rs2806561 0.765 rs681395 chr1:23500314 G/A cg19743168 chr1:23544995 NA 0.36 6.12 0.31 2.5e-9 Height; LIHC cis rs311392 0.967 rs4255114 chr8:55089450 G/A cg11783602 chr8:55087084 NA -0.31 -6.15 -0.32 2.19e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs4242434 0.672 rs10110443 chr8:22484296 C/G cg03733263 chr8:22462867 KIAA1967 0.71 12.1 0.55 2.59e-28 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs727505 0.954 rs1383748 chr7:124638201 A/T cg23710748 chr7:124431027 NA -0.33 -5.93 -0.31 7.5e-9 Lewy body disease; LIHC cis rs763121 0.853 rs4821810 chr22:39072098 C/G cg06022373 chr22:39101656 GTPBP1 0.75 15.33 0.64 9.55e-41 Menopause (age at onset); LIHC cis rs2549003 1.000 rs2548999 chr5:131831058 G/T cg21138405 chr5:131827807 IRF1 -0.39 -10.14 -0.48 2.65e-21 Asthma (sex interaction); LIHC cis rs11718455 0.585 rs6789465 chr3:43932045 G/A cg08738300 chr3:44038990 NA 0.37 6.34 0.32 7.23e-10 Coronary artery disease; LIHC cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg08067268 chr2:26466485 HADHB;HADHA 0.44 6.34 0.32 7.38e-10 Gut microbiome composition (summer); LIHC cis rs875971 0.862 rs12698521 chr7:65939489 T/C cg18876405 chr7:65276391 NA 0.38 6.86 0.35 3.22e-11 Aortic root size; LIHC cis rs5769765 1.000 rs764813 chr22:50286172 T/C cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.25e-16 Schizophrenia; LIHC cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg05590025 chr7:65112418 INTS4L2 -0.62 -6.82 -0.35 4.26e-11 Diabetic kidney disease; LIHC cis rs4423214 1.000 rs12808368 chr11:71170817 C/T cg05163923 chr11:71159392 DHCR7 0.89 13.62 0.59 4.7e-34 Vitamin D levels; LIHC cis rs11630290 0.592 rs4777332 chr15:64158112 A/G cg12036633 chr15:63758958 NA 0.63 6.81 0.35 4.47e-11 Iris characteristics; LIHC cis rs6424115 0.692 rs573361 chr1:24053674 A/T cg10978503 chr1:24200527 CNR2 0.29 6.76 0.34 5.86e-11 Immature fraction of reticulocytes; LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg02782426 chr3:40428986 ENTPD3 -0.34 -6.29 -0.32 9.49e-10 Renal cell carcinoma; LIHC cis rs66887589 0.967 rs2892869 chr4:120521297 T/C cg09307838 chr4:120376055 NA -0.48 -7.31 -0.37 1.89e-12 Diastolic blood pressure; LIHC cis rs7408868 1.000 rs2074617 chr19:15276055 C/G cg14696996 chr19:15285081 NOTCH3 0.53 7.1 0.36 7.41e-12 Pulse pressure; LIHC cis rs7131987 0.801 rs962866 chr12:29434147 A/G cg00204748 chr12:29376779 FAR2 0.35 6.61 0.34 1.47e-10 QT interval; LIHC cis rs11673344 0.864 rs8110696 chr19:37500351 G/T cg27390819 chr19:37464633 NA -0.53 -6.16 -0.32 2.09e-9 Obesity-related traits; LIHC cis rs7674212 0.510 rs6856593 chr4:104177699 T/C cg16532752 chr4:104119610 CENPE -0.4 -6.29 -0.32 9.89e-10 Type 2 diabetes; LIHC cis rs875971 0.964 rs9691480 chr7:65944306 A/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07627390 chr16:23652638 PALB2;DCTN5 0.53 6.89 0.35 2.65e-11 Lung function (FEV1/FVC); LIHC cis rs4900538 0.927 rs8005804 chr14:102957803 A/G cg18135206 chr14:102964638 TECPR2 0.95 16.4 0.66 5.36e-45 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs11864453 0.647 rs3852781 chr16:72123556 T/A cg01557791 chr16:72042693 DHODH -0.43 -7.09 -0.36 7.59e-12 Fibrinogen levels; LIHC cis rs9611565 0.546 rs5758430 chr22:42109844 G/T cg03806693 chr22:41940476 POLR3H 0.83 9.36 0.45 1.07e-18 Vitiligo; LIHC cis rs600806 0.713 rs10745305 chr1:110012148 A/G cg23091122 chr1:110024289 SYPL2 -0.5 -6.69 -0.34 9.06e-11 Intelligence (multi-trait analysis); LIHC cis rs4563143 0.663 rs10417671 chr19:29235335 T/C cg12756686 chr19:29218302 NA 0.38 6.55 0.33 2.05e-10 Methadone dose in opioid dependence; LIHC trans rs1422110 0.543 rs888804 chr5:85411181 G/A cg01787110 chr1:109008453 NBPF6 0.28 6.33 0.32 7.48e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs7904368 0.754 rs66491181 chr10:16849430 T/C cg23933602 chr10:16859644 RSU1 0.62 6.04 0.31 4.05e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg11766577 chr21:47581405 C21orf56 -0.42 -6.66 -0.34 1.11e-10 Testicular germ cell tumor; LIHC cis rs919433 0.680 rs788023 chr2:198283305 T/C cg03934865 chr2:198174659 NA 0.55 8.38 0.41 1.42e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4819052 0.851 rs2838850 chr21:46671445 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.88 0.39 4.27e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9549367 0.756 rs2302756 chr13:113900197 G/A cg00898013 chr13:113819073 PROZ 0.39 6.8 0.35 4.58e-11 Platelet distribution width; LIHC cis rs7613875 0.641 rs6446194 chr3:50067298 T/A cg05623727 chr3:50126028 RBM5 -0.34 -5.88 -0.3 9.72e-9 Body mass index; LIHC cis rs4450131 1.000 rs10901802 chr10:126354554 C/G cg20435097 chr10:126320824 FAM53B -0.5 -9.1 -0.44 7.69e-18 White blood cell count (basophil); LIHC cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg23205692 chr1:25664452 TMEM50A 0.39 6.26 0.32 1.17e-9 Erythrocyte sedimentation rate; LIHC cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.88 7.96 0.4 2.59e-14 Platelet count; LIHC cis rs12594515 1.000 rs12906442 chr15:45985254 C/A cg19682013 chr15:45996608 NA 0.4 7.12 0.36 6.34e-12 Waist circumference;Weight; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10950113 chr16:69166907 CHTF8;CIRH1A 0.46 6.25 0.32 1.19e-9 Pancreatic cancer; LIHC cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg08219700 chr8:58056026 NA 0.51 6.7 0.34 8.62e-11 Developmental language disorder (linguistic errors); LIHC cis rs208520 0.690 rs12213928 chr6:66762978 G/A cg07460842 chr6:66804631 NA 0.81 9.25 0.45 2.56e-18 Exhaled nitric oxide output; LIHC cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg21171335 chr12:122356390 WDR66 0.43 6.64 0.34 1.24e-10 Mean corpuscular volume; LIHC cis rs703842 0.892 rs1021469 chr12:58208164 C/T cg18357645 chr12:58087776 OS9 -0.44 -6.93 -0.35 2.07e-11 Multiple sclerosis; LIHC trans rs7613875 0.578 rs2526749 chr3:50076734 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.58 -0.34 1.82e-10 Body mass index; LIHC cis rs61656020 1 rs61656020 chr16:1882221 C/G cg26897989 chr16:1907736 C16orf73 -0.57 -7.11 -0.36 6.67e-12 Ankle injury; LIHC cis rs910316 0.737 rs175077 chr14:75506875 G/A cg11812906 chr14:75593930 NEK9 -0.74 -13.79 -0.6 1.05e-34 Height; LIHC cis rs13161895 1.000 rs35135297 chr5:179469532 T/C cg06664874 chr5:179499304 RNF130 0.61 7.56 0.38 3.66e-13 LDL cholesterol; LIHC cis rs6977660 1.000 rs35784097 chr7:19818848 A/G cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs7613875 0.580 rs2624819 chr3:50010571 G/T cg24110177 chr3:50126178 RBM5 -0.53 -8.6 -0.42 2.82e-16 Body mass index; LIHC cis rs921968 0.509 rs832813 chr2:219354569 T/C cg02985541 chr2:219472218 PLCD4 0.39 6.45 0.33 3.72e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3806843 0.868 rs2563291 chr5:140119599 T/A cg26395211 chr5:140044315 WDR55 0.41 6.12 0.31 2.63e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2576037 0.583 rs9916891 chr18:44493521 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.68 10.0 0.48 7.94e-21 Personality dimensions; LIHC cis rs9457247 0.935 rs9348211 chr6:167375173 G/C cg12798992 chr6:167411361 FGFR1OP -0.54 -8.28 -0.41 2.76e-15 Crohn's disease; LIHC cis rs10791323 0.693 rs10750544 chr11:133718740 A/G cg06766960 chr11:133703094 NA -0.59 -9.44 -0.45 5.84e-19 Childhood ear infection; LIHC cis rs3806843 1.000 rs10050455 chr5:140204650 A/G cg26395211 chr5:140044315 WDR55 -0.44 -6.56 -0.33 2.03e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs2952156 0.920 rs8078228 chr17:37834998 C/T cg00129232 chr17:37814104 STARD3 -0.53 -10.19 -0.48 1.76e-21 Asthma; LIHC cis rs3859192 0.561 rs9916158 chr17:38182229 G/T cg17467752 chr17:38218738 THRA -0.51 -8.97 -0.44 1.97e-17 White blood cell count; LIHC cis rs722599 0.599 rs8003660 chr14:75227098 T/C cg08847533 chr14:75593920 NEK9 0.48 7.44 0.37 8.33e-13 IgG glycosylation; LIHC cis rs4728302 0.869 rs7805864 chr7:133610390 G/A cg10665199 chr7:133106180 EXOC4 0.38 6.71 0.34 8.17e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs1000083 0.834 rs1833875 chr5:96594277 G/A ch.5.96698337R chr5:96672581 NA 0.86 6.94 0.35 2.02e-11 Cisplatin-induced ototoxicity; LIHC trans rs10506458 0.688 rs73127095 chr12:63418283 T/G cg22491629 chr6:157744540 C6orf35 -0.56 -10.22 -0.48 1.42e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs13108904 0.875 rs1564509 chr4:1236562 C/G cg05025164 chr4:1340916 KIAA1530 0.41 6.28 0.32 1.02e-9 Obesity-related traits; LIHC cis rs2153535 0.580 rs1577468 chr6:8444266 C/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs1401999 1.000 rs939336 chr3:183685534 A/G cg01324343 chr3:183735012 ABCC5 0.78 12.88 0.57 3.24e-31 Anterior chamber depth; LIHC cis rs56104184 0.775 rs55737338 chr19:49403141 A/G cg21252483 chr19:49399788 TULP2 -1.06 -12.19 -0.55 1.27e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs798766 1.000 rs798756 chr4:1707447 T/C cg15202627 chr4:1685555 FAM53A 0.48 5.75 0.3 1.95e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs12762955 0.561 rs10752022 chr10:1043798 C/T cg26597838 chr10:835615 NA -0.46 -5.81 -0.3 1.45e-8 Response to angiotensin II receptor blocker therapy; LIHC cis rs910316 0.763 rs175450 chr14:75590340 G/A cg11812906 chr14:75593930 NEK9 -0.75 -14.11 -0.61 6.07e-36 Height; LIHC cis rs1580019 0.563 rs10486509 chr7:32585443 C/G cg06627557 chr7:32535165 LSM5;AVL9 -1.1 -23.95 -0.79 4.1e-75 Cognitive ability; LIHC cis rs1023500 0.505 rs134899 chr22:42683030 T/G cg04733989 chr22:42467013 NAGA 0.44 6.59 0.34 1.71e-10 Schizophrenia; LIHC cis rs801193 0.935 rs11772264 chr7:66176387 T/C cg11764359 chr7:65958608 NA 0.71 10.5 0.49 1.5e-22 Aortic root size; LIHC trans rs4596713 0.507 rs10115134 chr9:71800562 T/C cg16512924 chr15:28394682 HERC2 0.39 6.28 0.32 1e-9 Headache; LIHC cis rs72772090 0.710 rs11739280 chr5:96074147 C/T cg17330273 chr5:96107758 CAST;ERAP1 0.65 7.55 0.38 4.07e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2197308 0.765 rs11182900 chr12:37934009 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs11190604 1.000 rs7078799 chr10:102301447 G/A cg07080220 chr10:102295463 HIF1AN 0.52 7.23 0.36 3.13e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17854409 1.000 rs66956644 chr20:61484499 T/C cg07645718 chr20:61493192 TCFL5 0.74 6.16 0.32 2.03e-9 Obesity-related traits; LIHC cis rs9811920 0.609 rs10936005 chr3:99674093 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 7.16 0.36 4.94e-12 Axial length; LIHC cis rs13108904 0.818 rs3775099 chr4:1232510 C/G cg05665937 chr4:1216051 CTBP1 0.47 6.42 0.33 4.67e-10 Obesity-related traits; LIHC cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg08888203 chr3:10149979 C3orf24 0.61 6.92 0.35 2.29e-11 Alzheimer's disease; LIHC cis rs7116495 0.609 rs10736780 chr11:71650241 T/C cg07596299 chr11:71824057 C11orf51 -0.75 -5.72 -0.3 2.3e-8 Severe influenza A (H1N1) infection; LIHC cis rs533581 0.866 rs4995274 chr16:88970040 T/C cg03970086 chr16:88974840 CBFA2T3 0.37 7.43 0.37 8.53e-13 Social autistic-like traits; LIHC cis rs12365397 0.775 rs11037365 chr11:43243675 C/T cg16667275 chr11:43333495 API5 0.41 6.13 0.31 2.36e-9 Migraine; LIHC cis rs1707322 0.506 rs2991983 chr1:46079391 T/C cg03146154 chr1:46216737 IPP -0.56 -9.19 -0.45 3.87e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12220238 0.915 rs11000945 chr10:76030739 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.99 0.31 5.26e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs17401966 0.838 rs1556917 chr1:10400990 G/T cg19773385 chr1:10388646 KIF1B -0.39 -6.83 -0.35 3.86e-11 Hepatocellular carcinoma; LIHC cis rs9457247 0.765 rs3752520 chr6:167436159 T/C cg12798992 chr6:167411361 FGFR1OP 0.48 7.32 0.37 1.77e-12 Crohn's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06221861 chr7:100425075 EPHB4 0.43 6.53 0.33 2.38e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs992157 0.661 rs17653757 chr2:219109364 G/C cg00012203 chr2:219082015 ARPC2 0.92 16.75 0.67 2.14e-46 Colorectal cancer; LIHC cis rs7520050 0.966 rs12410071 chr1:46358886 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.42 6.13 0.31 2.45e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4759375 1.000 rs28660993 chr12:123875394 C/T cg00376283 chr12:123451042 ABCB9 0.49 6.31 0.32 8.6e-10 HDL cholesterol; LIHC trans rs875971 0.617 rs810400 chr7:66022889 G/C cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg13047869 chr3:10149882 C3orf24 0.5 6.16 0.32 2.08e-9 Alzheimer's disease; LIHC cis rs3762637 1.000 rs13321097 chr3:122162007 C/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs929354 0.772 rs2023975 chr7:157012096 G/A cg17757837 chr7:157058334 UBE3C 0.73 11.96 0.54 9.11e-28 Body mass index; LIHC cis rs7937890 0.572 rs2597218 chr11:14532338 C/T cg02886208 chr11:14281011 SPON1 -0.48 -6.54 -0.33 2.28e-10 Mitochondrial DNA levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18363668 chr6:26026694 NA 0.39 6.05 0.31 3.9e-9 Cognitive function; LIHC cis rs5769765 0.865 rs3788730 chr22:50244695 C/T cg26441486 chr22:50317300 CRELD2 -0.35 -6.33 -0.32 7.6e-10 Schizophrenia; LIHC cis rs7408868 1.000 rs2074618 chr19:15276143 C/T cg14696996 chr19:15285081 NOTCH3 0.53 7.1 0.36 7.41e-12 Pulse pressure; LIHC cis rs9868809 0.772 rs9809222 chr3:48714411 C/T cg07636037 chr3:49044803 WDR6 -0.59 -6.74 -0.34 6.5500000000000006e-11 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs8077889 0.956 rs4793026 chr17:41850508 A/G cg26893861 chr17:41843967 DUSP3 0.88 9.88 0.47 2.04e-20 Triglycerides; LIHC cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg12310025 chr6:25882481 NA -0.64 -8.98 -0.44 1.92e-17 Blood metabolite levels; LIHC cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg23205692 chr1:25664452 TMEM50A 0.4 6.42 0.33 4.45e-10 Erythrocyte sedimentation rate; LIHC cis rs1371867 0.875 rs1788169 chr8:101326314 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -8.92 -0.43 2.79e-17 Atrioventricular conduction; LIHC cis rs1577917 0.958 rs2875456 chr6:86602284 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.22 -0.36 3.45e-12 Response to antipsychotic treatment; LIHC cis rs988712 0.576 rs6265 chr11:27679916 C/T cg18117895 chr11:27722066 BDNF 0.51 6.73 0.34 7.36e-11 Obesity; LIHC cis rs600806 0.888 rs12046539 chr1:109875415 C/T cg23091122 chr1:110024289 SYPL2 -0.45 -5.93 -0.31 7.4e-9 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.521 rs13084731 chr3:161086020 G/A cg17135325 chr3:160939158 NMD3 0.42 6.09 0.31 3.07e-9 Morning vs. evening chronotype; LIHC cis rs1707322 1.000 rs12124291 chr1:46432132 G/A cg03146154 chr1:46216737 IPP 0.47 7.77 0.39 9.48e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg04546413 chr19:29218101 NA 0.56 10.28 0.49 8.91e-22 Methadone dose in opioid dependence; LIHC cis rs11971779 0.625 rs2355784 chr7:139072493 G/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg26939375 chr7:64535504 NA 0.47 7.18 0.36 4.4e-12 Aortic root size; LIHC cis rs7762018 0.891 rs12529402 chr6:170147675 A/T cg19338460 chr6:170058176 WDR27 -0.38 -5.9 -0.3 8.61e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg26939375 chr7:64535504 NA -0.42 -7.27 -0.37 2.4e-12 Calcium levels; LIHC cis rs56104184 0.775 rs73061697 chr19:49400000 C/T cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7945718 0.591 rs10466378 chr11:12841992 G/A cg25843174 chr11:12811716 TEAD1 0.35 7.92 0.39 3.42e-14 Educational attainment (years of education); LIHC cis rs7772486 0.875 rs9403765 chr6:146368041 C/T cg23711669 chr6:146136114 FBXO30 -0.6 -10.42 -0.49 2.88e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs3741404 0.665 rs12418535 chr11:63910980 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.95 16.09 0.66 9.11e-44 Platelet count; LIHC cis rs9534288 0.957 rs2404731 chr13:46618384 T/C cg15192986 chr13:46630673 CPB2 -0.58 -8.61 -0.42 2.66e-16 Blood protein levels; LIHC cis rs10504229 0.511 rs16921553 chr8:57979314 T/C cg20607798 chr8:58055168 NA 0.5 5.81 0.3 1.4e-8 Developmental language disorder (linguistic errors); LIHC cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg27170947 chr2:26402098 FAM59B -0.65 -8.36 -0.41 1.57e-15 Gut microbiome composition (summer); LIHC trans rs911555 0.755 rs9671414 chr14:103967299 C/T cg17675199 chr6:35436792 RPL10A -0.43 -8.59 -0.42 3.14e-16 Intelligence (multi-trait analysis); LIHC cis rs4638749 0.677 rs13423385 chr2:108826435 C/G cg25838818 chr2:108905173 SULT1C2 -0.39 -6.99 -0.35 1.43e-11 Blood pressure; LIHC cis rs2074585 0.802 rs2589940 chr15:90931363 C/T cg22089800 chr15:90895588 ZNF774 0.57 7.83 0.39 6.29e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs78545713 0.881 rs74608402 chr6:26240474 C/T cg16070018 chr6:26224392 HIST1H3E 0.76 7.64 0.38 2.16e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.49 0.56 9.6e-30 Prudent dietary pattern; LIHC cis rs1577917 0.740 rs6926049 chr6:86266133 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.44 7.6 0.38 2.95e-13 Response to antipsychotic treatment; LIHC cis rs7223966 1.000 rs17549954 chr17:61707032 A/G cg05941027 chr17:61774174 LIMD2 0.36 7.5 0.38 5.41e-13 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02952972 chr11:972247 AP2A2 -0.45 -6.52 -0.33 2.55e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4423214 1.000 rs11233746 chr11:71171440 A/G cg05163923 chr11:71159392 DHCR7 0.86 13.2 0.58 1.88e-32 Vitamin D levels; LIHC cis rs6429082 0.715 rs2131924 chr1:235580928 G/A cg26050004 chr1:235667680 B3GALNT2 -0.49 -7.33 -0.37 1.71e-12 Adiposity; LIHC trans rs6952808 0.624 rs60137119 chr7:2083664 A/G cg04565464 chr8:145669602 NFKBIL2 0.38 6.2 0.32 1.59e-9 Bipolar disorder and schizophrenia; LIHC cis rs9303401 0.538 rs2240258 chr17:56458183 C/A cg25039879 chr17:56429692 SUPT4H1 0.84 9.29 0.45 1.85e-18 Cognitive test performance; LIHC cis rs523522 0.962 rs3893104 chr12:120903936 G/A cg12219531 chr12:120966889 COQ5 0.66 12.71 0.57 1.45e-30 High light scatter reticulocyte count; LIHC cis rs7833986 0.501 rs2953897 chr8:56980569 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.76 0.43 9.13e-17 Height; LIHC cis rs68170813 0.559 rs1548523 chr7:106944408 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg18252515 chr7:66147081 NA -1.25 -16.9 -0.67 5.3e-47 Diabetic kidney disease; LIHC cis rs7267979 0.966 rs2257461 chr20:25265554 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC trans rs2727020 0.595 rs10839281 chr11:49483373 A/C cg15704280 chr7:45808275 SEPT13 -0.99 -21.48 -0.76 2.13e-65 Coronary artery disease; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg14671364 chr1:107599128 PRMT6 0.48 7.2 0.36 3.8e-12 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg18306943 chr3:40428807 ENTPD3 -0.42 -7.35 -0.37 1.49e-12 Renal cell carcinoma; LIHC cis rs34330 0.562 rs12229100 chr12:12865836 A/G cg04607235 chr12:12878440 APOLD1 0.75 9.4 0.45 7.99e-19 Systemic lupus erythematosus; LIHC trans rs11098499 0.865 rs9994730 chr4:120381564 A/C cg25214090 chr10:38739885 LOC399744 0.6 9.81 0.47 3.5e-20 Corneal astigmatism; LIHC cis rs7523273 0.565 rs4081159 chr1:207885479 G/A cg22525895 chr1:207977042 MIR29B2 0.49 7.26 0.37 2.6e-12 Schizophrenia; LIHC cis rs7520050 0.966 rs4134386 chr1:46395089 G/A cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs9325144 0.555 rs1843867 chr12:38703855 A/G cg26384229 chr12:38710491 ALG10B -0.62 -8.61 -0.42 2.77e-16 Morning vs. evening chronotype; LIHC cis rs2832191 0.791 rs2832199 chr21:30498501 G/A cg24692254 chr21:30365293 RNF160 -0.59 -10.27 -0.49 9.66e-22 Dental caries; LIHC cis rs17021463 0.934 rs28403447 chr4:95257753 G/A cg11021082 chr4:95130006 SMARCAD1 0.44 7.91 0.39 3.66e-14 Testicular germ cell tumor; LIHC cis rs11583043 0.918 rs6675403 chr1:101418569 T/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.59 8.0 0.4 2e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs12142240 0.659 rs1984491 chr1:46858607 T/G cg14993813 chr1:46806288 NSUN4 -0.66 -5.97 -0.31 5.89e-9 Menopause (age at onset); LIHC cis rs9733 0.566 rs11204675 chr1:150570985 A/C cg17724175 chr1:150552817 MCL1 -0.39 -7.85 -0.39 5.28e-14 Tonsillectomy; LIHC cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.75e-9 Menopause (age at onset); LIHC cis rs4561483 0.801 rs33640 chr16:11986874 C/T cg08843971 chr16:11963173 GSPT1 -0.43 -8.53 -0.42 4.94e-16 Testicular germ cell tumor; LIHC cis rs1059312 0.808 rs12816551 chr12:129295616 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.77 -16.8 -0.67 1.3e-46 Systemic lupus erythematosus; LIHC trans rs208520 0.837 rs208488 chr6:66926902 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.24 -0.41 3.72e-15 Exhaled nitric oxide output; LIHC cis rs11246807 1 rs11246807 chr12:132275765 C/T cg13251533 chr12:132286017 NA 0.54 6.57 0.33 1.89e-10 Psychosis proneness (perceptual aberration scale); LIHC cis rs8103278 1.000 rs7252126 chr19:46302374 T/A cg11657440 chr19:46296263 DMWD -0.53 -8.29 -0.41 2.56e-15 Coronary artery disease; LIHC cis rs7412746 0.634 rs4451553 chr1:150937329 C/T cg15448220 chr1:150897856 SETDB1 0.44 6.84 0.35 3.62e-11 Melanoma; LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs1707322 1.000 rs10890365 chr1:46359348 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.17 0.32 1.96e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2067615 0.579 rs10861665 chr12:107193836 T/C cg15890332 chr12:107067104 RFX4 0.26 6.07 0.31 3.33e-9 Heart rate; LIHC cis rs12971120 1.000 rs12971120 chr18:72174023 A/G cg25817165 chr18:72167213 CNDP2 -0.7 -12.51 -0.56 8.05e-30 Refractive error; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg08251337 chr16:81040389 C16orf61;CENPN -0.38 -6.19 -0.32 1.69e-9 Neuroblastoma; LIHC cis rs3741404 0.583 rs640999 chr11:63869425 C/A cg18225595 chr11:63971243 STIP1 0.45 7.27 0.37 2.4e-12 Platelet count; LIHC cis rs151997 0.925 rs27579 chr5:50165147 G/A cg06027927 chr5:50259733 NA 0.56 7.31 0.37 1.88e-12 Callous-unemotional behaviour; LIHC cis rs8027181 0.839 rs2304597 chr15:73052431 A/G cg25632853 chr15:73088954 NA 0.36 5.93 0.31 7.48e-9 Triglyceride levels; LIHC cis rs79057730 0.599 rs34411410 chr7:811721 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.79 9.06 0.44 1.04e-17 Initial pursuit acceleration; LIHC cis rs892961 0.965 rs312856 chr17:75401598 A/G cg01320579 chr17:75405842 SEPT9 0.49 8.77 0.43 8.4e-17 Airflow obstruction; LIHC cis rs4076764 0.535 rs4409627 chr1:163382050 A/G cg24596788 chr1:163392923 NA 0.22 7.25 0.37 2.71e-12 Motion sickness; LIHC trans rs6598955 0.671 rs10902735 chr1:26617936 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.21 -0.41 4.62e-15 Obesity-related traits; LIHC cis rs4727027 0.866 rs12666477 chr7:148812322 A/G cg23583168 chr7:148888333 NA -0.68 -9.47 -0.46 4.79e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2228479 0.717 rs2286392 chr16:89809549 A/G cg04013166 chr16:89971882 TCF25 0.48 6.08 0.31 3.28e-9 Skin colour saturation; LIHC cis rs1986734 0.576 rs12503749 chr4:77418383 T/C cg24201034 chr4:77507246 SHROOM3 -0.38 -6.12 -0.31 2.56e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.07e-26 Alzheimer's disease; LIHC cis rs17685 0.753 rs1637039 chr7:75693009 C/T cg04610667 chr7:75704037 NA -0.35 -6.25 -0.32 1.23e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6582630 0.555 rs35284307 chr12:38509999 T/G cg13010199 chr12:38710504 ALG10B 0.46 6.22 0.32 1.42e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg12463550 chr7:65579703 CRCP 0.69 7.1 0.36 7.46e-12 Diabetic kidney disease; LIHC cis rs16828019 0.852 rs2300649 chr1:41569203 T/C cg03962019 chr1:41807865 NA 0.51 7.43 0.37 8.87e-13 Intelligence (multi-trait analysis); LIHC cis rs1843834 0.898 rs12623277 chr2:225548072 T/G cg22455342 chr2:225449267 CUL3 0.43 6.2 0.32 1.63e-9 IgE levels in asthmatics (D.p. specific); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg08951907 chr17:18218556 TOP3A;SMCR8 -0.41 -6.09 -0.31 3.09e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs801193 0.569 rs2659892 chr7:66200305 A/G cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.34e-11 Aortic root size; LIHC cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg02579736 chr3:10068473 FANCD2;CIDECP -0.97 -12.1 -0.55 2.75e-28 Alzheimer's disease; LIHC cis rs11702148 0.552 rs2154583 chr21:34888940 T/G cg14850771 chr21:34775459 IFNGR2 0.49 8.03 0.4 1.55e-14 Mean corpuscular hemoglobin; LIHC cis rs909002 0.800 rs1061770 chr1:32096265 A/G cg13919466 chr1:32135498 COL16A1 -0.34 -6.33 -0.32 7.68e-10 Intelligence (multi-trait analysis); LIHC cis rs651907 0.557 rs34947019 chr3:101532235 C/T cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.86 -0.3 1.09e-8 Colorectal cancer; LIHC cis rs11112613 0.713 rs11112586 chr12:105939816 C/T cg03607813 chr12:105948248 NA 0.56 10.42 0.49 2.84e-22 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs2952156 0.959 rs2941503 chr17:37828745 A/G cg00129232 chr17:37814104 STARD3 -0.51 -9.37 -0.45 1.04e-18 Asthma; LIHC cis rs10876993 0.928 rs813854 chr12:58071347 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.05 -0.31 3.75e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs6540556 0.634 rs11485195 chr1:209891738 T/C cg05527609 chr1:210001259 C1orf107 -0.54 -7.52 -0.38 4.9e-13 Red blood cell count; LIHC cis rs1577917 0.739 rs9450318 chr6:86427177 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 10.3 0.49 7.75e-22 Response to antipsychotic treatment; LIHC cis rs36051895 0.664 rs3780371 chr9:5095191 T/A cg02405213 chr9:5042618 JAK2 -0.66 -10.97 -0.51 3.34e-24 Pediatric autoimmune diseases; LIHC cis rs7264396 1.000 rs224433 chr20:34153850 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.38 -6.62 -0.34 1.41e-10 Total cholesterol levels; LIHC cis rs6582630 0.502 rs11520276 chr12:38359216 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.24 0.41 3.8e-15 Drug-induced liver injury (flucloxacillin); LIHC trans rs3783890 0.887 rs11626995 chr14:93815892 C/T cg02802420 chr16:69363236 PDF;COG8 0.32 6.19 0.32 1.69e-9 Body mass index; LIHC cis rs9916302 0.904 rs11078897 chr17:37415870 C/T cg07936489 chr17:37558343 FBXL20 -0.84 -13.74 -0.6 1.69e-34 Glomerular filtration rate (creatinine); LIHC cis rs3812111 0.676 rs2351141 chr6:116501983 G/A cg08036074 chr6:116424633 NT5DC1 -0.52 -8.71 -0.43 1.33e-16 Age-related macular degeneration; LIHC cis rs55665837 1.000 rs10832268 chr11:14465068 C/A cg19336497 chr11:14380999 RRAS2 -0.45 -8.29 -0.41 2.53e-15 Vitamin D levels; LIHC cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg27170947 chr2:26402098 FAM59B 0.66 8.34 0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs9911578 0.967 rs11656413 chr17:57082013 A/C cg12560992 chr17:57184187 TRIM37 -0.96 -17.53 -0.69 1.56e-49 Intelligence (multi-trait analysis); LIHC cis rs2070488 0.965 rs3762788 chr3:38493852 C/A cg24069376 chr3:38537580 EXOG 0.43 7.91 0.39 3.59e-14 Electrocardiographic conduction measures; LIHC cis rs751728 1.000 rs4711351 chr6:33754592 G/A cg25922239 chr6:33757077 LEMD2 0.44 7.34 0.37 1.57e-12 Crohn's disease; LIHC cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.546 rs1335640 chr6:8485325 A/C cg23788917 chr6:8435910 SLC35B3 0.59 8.43 0.41 9.85e-16 Motion sickness; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.12 0.4 8.4e-15 Height; LIHC cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg07308232 chr7:1071921 C7orf50 -0.48 -7.7 -0.38 1.51e-13 Longevity;Endometriosis; LIHC cis rs4563143 0.514 rs73029076 chr19:29292032 G/T cg14983838 chr19:29218262 NA 0.44 6.45 0.33 3.77e-10 Methadone dose in opioid dependence; LIHC cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.52 9.05 0.44 1.1e-17 Electroencephalogram traits; LIHC cis rs9916302 0.706 rs28482878 chr17:37497100 A/G cg07936489 chr17:37558343 FBXL20 0.85 12.19 0.55 1.26e-28 Glomerular filtration rate (creatinine); LIHC trans rs4332037 0.539 rs11764590 chr7:2032803 C/T cg11693508 chr17:37793320 STARD3 0.65 6.55 0.33 2.07e-10 Bipolar disorder; LIHC trans rs7615952 0.688 rs12638240 chr3:125541238 G/A cg07211511 chr3:129823064 LOC729375 -0.49 -7.57 -0.38 3.46e-13 Blood pressure (smoking interaction); LIHC cis rs34779708 0.931 rs12771399 chr10:35452377 C/T cg03585969 chr10:35415529 CREM 0.86 12.81 0.57 5.99e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.42 6.36 0.33 6.51e-10 Tuberculosis; LIHC trans rs1814175 0.817 rs7947526 chr11:49983654 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.27 -0.78 1.78e-72 Height; LIHC cis rs611744 0.934 rs624311 chr8:109204437 A/G cg18478394 chr8:109455254 TTC35 0.4 6.97 0.35 1.63e-11 Dupuytren's disease; LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs10911363 0.592 rs10911354 chr1:183489278 G/A cg09173681 chr1:183549694 NCF2 0.54 9.34 0.45 1.26e-18 Systemic lupus erythematosus; LIHC cis rs7903847 0.642 rs1537646 chr10:99149922 T/C cg06359132 chr10:99160096 RRP12 -0.41 -6.42 -0.33 4.43e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs600806 0.778 rs2152924 chr1:110011701 G/A cg11161837 chr1:110010384 SYPL2 0.46 6.32 0.32 8.37e-10 Intelligence (multi-trait analysis); LIHC cis rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14838474 chr12:21654441 RECQL;GOLT1B -0.39 -6.07 -0.31 3.42e-9 Bilirubin levels; LIHC cis rs7772486 0.754 rs1415746 chr6:146077107 A/G cg23711669 chr6:146136114 FBXO30 -0.76 -14.31 -0.61 1e-36 Lobe attachment (rater-scored or self-reported); LIHC cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg26818010 chr10:134567672 INPP5A -0.8 -9.8 -0.47 3.9e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2257205 0.667 rs28605629 chr17:56906157 C/A cg05425664 chr17:57184151 TRIM37 -0.59 -6.46 -0.33 3.5e-10 Pancreatic cancer; LIHC cis rs12908161 1.000 rs11638290 chr15:85227636 C/T cg03959625 chr15:84868606 LOC388152 0.42 5.94 0.31 7.06e-9 Schizophrenia; LIHC cis rs240764 0.782 rs151637 chr6:101104191 C/T cg09795085 chr6:101329169 ASCC3 0.53 7.46 0.37 7.07e-13 Neuroticism; LIHC cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg02290350 chr8:58132656 NA 0.46 9.4 0.45 8.2e-19 Developmental language disorder (linguistic errors); LIHC cis rs2980439 0.525 rs2980508 chr8:8171732 C/T cg14343924 chr8:8086146 FLJ10661 0.47 6.43 0.33 4.32e-10 Neuroticism; LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.875 rs2474356 chr6:146296798 G/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.28 -0.32 1e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9583531 0.629 rs7991766 chr13:111380684 A/G cg15841412 chr13:111365552 ING1 0.48 5.88 0.3 9.67e-9 Coronary artery disease; LIHC cis rs4665809 1.000 rs4665309 chr2:26335502 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs7552404 1.000 rs6672180 chr1:76123973 C/G cg10523679 chr1:76189770 ACADM 0.66 9.19 0.45 3.9e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs10198293 chr2:99602929 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.58 -0.53 2.12e-26 Chronic sinus infection; LIHC cis rs1862618 0.853 rs252910 chr5:56192983 G/A cg24549020 chr5:56110836 MAP3K1 0.54 6.8 0.35 4.63e-11 Initial pursuit acceleration; LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.45 -7.11 -0.36 6.62e-12 Prudent dietary pattern; LIHC cis rs4714291 0.963 rs2395543 chr6:39965020 A/G cg16345906 chr6:40101885 NA -0.29 -5.84 -0.3 1.23e-8 Strep throat; LIHC cis rs4853012 0.838 rs58759652 chr2:74344902 A/T cg20011983 chr2:74347215 NA -0.39 -5.75 -0.3 2e-8 Gestational age at birth (maternal effect); LIHC trans rs6489882 0.703 rs10774672 chr12:113360737 G/T cg10175203 chr3:128143634 NA 0.4 6.46 0.33 3.53e-10 Chronic lymphocytic leukemia; LIHC cis rs910316 0.789 rs12894419 chr14:75471802 C/T cg08847533 chr14:75593920 NEK9 0.89 18.32 0.7 1.06e-52 Height; LIHC cis rs3096299 0.685 rs4785568 chr16:89553707 A/G cg08392591 chr16:89556376 ANKRD11 0.56 8.96 0.44 2.22e-17 Multiple myeloma (IgH translocation); LIHC trans rs72829446 0.530 rs72827503 chr17:7371268 G/T cg08566640 chr11:64091735 NA -0.69 -6.15 -0.32 2.14e-9 Androgen levels; LIHC cis rs6121246 0.697 rs6120970 chr20:30232452 C/T cg13852791 chr20:30311386 BCL2L1 0.82 8.24 0.41 3.62e-15 Mean corpuscular hemoglobin; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.87 0.57 3.48e-31 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.78 0.8 2.34e-78 Prudent dietary pattern; LIHC cis rs1008375 1.000 rs6854733 chr4:17640526 C/T cg02297831 chr4:17616191 MED28 0.49 7.79 0.39 7.98e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7700895 0.737 rs6879652 chr5:95227462 T/C cg10483112 chr5:95245456 ELL2 -0.33 -5.82 -0.3 1.38e-8 IgG glycosylation; LIHC cis rs6963495 0.818 rs711430 chr7:105167969 A/G cg19920283 chr7:105172520 RINT1 0.76 8.53 0.42 4.87e-16 Bipolar disorder (body mass index interaction); LIHC cis rs7918232 0.941 rs788220 chr10:27447205 T/C cg14240646 chr10:27532245 ACBD5 0.69 6.4 0.33 5.12e-10 Breast cancer; LIHC cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 9.37 0.45 9.76e-19 Mean platelet volume; LIHC cis rs4699052 0.963 rs7657390 chr4:104213114 T/A cg16532752 chr4:104119610 CENPE -0.39 -6.29 -0.32 9.82e-10 Testicular germ cell tumor; LIHC cis rs8192917 1.000 rs8192917 chr14:25102160 C/T cg08766149 chr14:25103301 GZMB -0.34 -7.87 -0.39 4.81e-14 Vitiligo; LIHC cis rs17685 0.753 rs7804598 chr7:75702578 C/T cg16684958 chr7:75615977 POR 0.51 8.59 0.42 3.18e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg07424592 chr7:64974309 NA -0.8 -9.31 -0.45 1.58e-18 Diabetic kidney disease; LIHC cis rs73001065 0.636 rs10415849 chr19:19505087 C/T cg03709012 chr19:19516395 GATAD2A 0.92 10.19 0.48 1.84e-21 LDL cholesterol; LIHC cis rs11785400 1.000 rs3824208 chr8:143743653 C/G cg10596483 chr8:143751796 JRK 0.51 8.32 0.41 2.06e-15 Schizophrenia; LIHC cis rs929354 0.553 rs34498858 chr7:156931337 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.89 0.3 9.39e-9 Body mass index; LIHC cis rs8017423 0.967 rs28424204 chr14:90705669 G/C cg04374321 chr14:90722782 PSMC1 0.75 14.41 0.61 4.2e-37 Mortality in heart failure; LIHC cis rs9814567 1.000 rs6800862 chr3:134228628 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs595982 0.559 rs17206700 chr19:49361255 A/G cg15549821 chr19:49342101 PLEKHA4 -0.63 -6.29 -0.32 9.81e-10 Red cell distribution width; LIHC trans rs8117834 0.574 rs73076234 chr20:8081654 A/C cg00593689 chr4:53575888 NA 0.37 6.17 0.32 1.89e-9 Chronic kidney disease; LIHC cis rs2795502 0.938 rs2744085 chr10:43341976 C/T cg27426351 chr10:43362370 NA 0.46 5.84 0.3 1.22e-8 Blood protein levels; LIHC cis rs7917772 0.636 rs2249845 chr10:104512095 A/G cg22532475 chr10:104410764 TRIM8 0.37 6.49 0.33 3.06e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11031096 0.678 rs11031220 chr11:4197638 G/A cg18678763 chr11:4115507 RRM1 -0.41 -5.95 -0.31 6.62e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs861318 0.702 rs2814770 chr1:159012772 A/G cg11003133 chr1:159046391 AIM2 0.33 6.73 0.34 7.27e-11 Obesity-related traits; LIHC cis rs644799 0.526 rs534973 chr11:95633624 A/T cg25622487 chr11:95524042 FAM76B;CEP57 0.56 7.9 0.39 3.94e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2292096 0.929 rs6667419 chr1:200756197 G/C cg07580975 chr1:200843333 NA 0.43 6.13 0.31 2.47e-9 Epilepsy; LIHC trans rs4619890 0.641 rs6446622 chr4:7812674 G/A cg12868349 chr11:71639594 RNF121;LOC100133315 -0.51 -6.4 -0.33 5.27e-10 Glaucoma (primary open-angle); LIHC cis rs6867032 0.958 rs4463207 chr5:2017118 G/T cg26168224 chr5:2018326 NA 0.3 7.45 0.37 7.61e-13 Gut microbiome composition (winter); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24926775 chr1:151584391 SNX27 0.46 6.66 0.34 1.11e-10 Pancreatic cancer; LIHC cis rs9590974 0.663 rs1216859 chr13:47231911 G/A cg04092803 chr13:47240378 LRCH1 0.26 5.74 0.3 2.04e-8 PR segment; LIHC trans rs66887589 0.777 rs4643791 chr4:120265619 A/G cg25214090 chr10:38739885 LOC399744 -0.37 -6.1 -0.31 2.85e-9 Diastolic blood pressure; LIHC cis rs57244997 0.872 rs11759694 chr6:162405705 C/G cg17173639 chr6:162384350 PARK2 0.55 6.95 0.35 1.86e-11 Mosquito bite size; LIHC cis rs4423214 0.524 rs4944046 chr11:71123794 C/G cg05163923 chr11:71159392 DHCR7 0.57 8.28 0.41 2.9e-15 Vitamin D levels; LIHC cis rs74181299 0.684 rs6713746 chr2:65324492 G/C cg05010058 chr2:65284262 CEP68 -0.4 -6.71 -0.34 8.22e-11 Pulse pressure; LIHC cis rs9326248 1.000 rs3736120 chr11:117032125 G/T cg15534755 chr11:117069859 TAGLN 0.36 6.04 0.31 4.05e-9 Blood protein levels; LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg20570016 chr1:156261298 TMEM79 0.37 6.02 0.31 4.54e-9 Tonsillectomy; LIHC cis rs74233809 0.786 rs11191564 chr10:104878543 C/T cg03493300 chr10:104813866 CNNM2 0.47 6.34 0.32 7.15e-10 Birth weight; LIHC cis rs7208859 0.623 rs122898 chr17:28905254 C/T cg14067834 chr17:29058358 SUZ12P -0.67 -6.83 -0.35 3.89e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2380220 0.872 rs115871915 chr6:95934180 T/C cg04719120 chr6:96025338 MANEA -0.59 -6.21 -0.32 1.53e-9 Behavioural disinhibition (generation interaction); LIHC cis rs66573146 0.572 rs73199995 chr4:6955801 G/C cg00086871 chr4:6988644 TBC1D14 0.8 6.06 0.31 3.61e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2839186 0.967 rs17176131 chr21:47705237 T/C cg05896524 chr21:47604654 C21orf56 0.44 6.62 0.34 1.38e-10 Testicular germ cell tumor; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg11060661 chr22:24314208 DDT;DDTL 0.6 10.22 0.48 1.4e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs5758511 0.680 rs17002902 chr22:42625509 C/G cg00645731 chr22:42541494 CYP2D7P1 0.53 8.49 0.42 6.45e-16 Birth weight; LIHC cis rs12477438 0.765 rs6735801 chr2:99657995 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.5 -0.38 5.38e-13 Chronic sinus infection; LIHC cis rs11583043 0.918 rs3850453 chr1:101408933 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.48 0.46 4.48e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg19318889 chr4:1322082 MAEA 0.65 10.25 0.48 1.16e-21 Longevity; LIHC cis rs2180341 0.920 rs1073931 chr6:127681762 A/T cg27446573 chr6:127587934 RNF146 1.07 16.77 0.67 1.67e-46 Breast cancer; LIHC cis rs9640161 0.658 rs60467296 chr7:150015471 G/A cg21361702 chr7:150065534 REPIN1 0.46 6.42 0.33 4.55e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs66569888 0.507 rs11673736 chr2:106886935 T/C cg15412446 chr2:106886593 NA -0.74 -13.56 -0.59 8.03e-34 Facial morphology (factor 23); LIHC cis rs6912958 0.781 rs9450755 chr6:88303702 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.63 -0.38 2.35e-13 Monocyte percentage of white cells; LIHC cis rs780096 0.526 rs11682621 chr2:27749669 G/A cg22903471 chr2:27725779 GCKR -0.5 -8.29 -0.41 2.65e-15 Total body bone mineral density; LIHC cis rs3812111 0.615 rs9320557 chr6:116462083 A/C cg08036074 chr6:116424633 NT5DC1 -0.5 -8.64 -0.42 2.14e-16 Age-related macular degeneration; LIHC cis rs6060717 0.536 rs2425104 chr20:34312346 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Hip circumference adjusted for BMI; LIHC cis rs7027203 0.828 rs10122041 chr9:96615517 A/G cg14598338 chr9:96623480 NA -0.34 -6.84 -0.35 3.76e-11 DNA methylation (variation); LIHC trans rs12310956 0.532 rs11052948 chr12:33981973 T/C cg26384229 chr12:38710491 ALG10B 0.56 7.52 0.38 4.82e-13 Morning vs. evening chronotype; LIHC trans rs1552244 0.572 rs3894321 chr3:10168892 A/C cg26113512 chr3:38035601 VILL -0.53 -6.12 -0.31 2.56e-9 Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26618056 chr16:25043323 NA 0.55 7.69 0.38 1.63e-13 Lung function (FEV1/FVC); LIHC cis rs1008375 0.966 rs2872957 chr4:17651757 C/A cg02297831 chr4:17616191 MED28 0.5 7.8 0.39 7.38e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2404602 0.647 rs12439141 chr15:77095423 T/C cg23625390 chr15:77176239 SCAPER -0.54 -9.04 -0.44 1.23e-17 Blood metabolite levels; LIHC cis rs10540 1.000 rs12786555 chr11:506229 C/T cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.22e-11 Body mass index; LIHC cis rs3793683 0.928 rs10781585 chr10:134553369 C/A cg27297192 chr10:134578999 INPP5A -0.52 -8.25 -0.41 3.58e-15 Migraine; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg12334488 chr2:20871173 GDF7 -0.47 -8.98 -0.44 1.88e-17 Abdominal aortic aneurysm; LIHC cis rs1997103 0.954 rs6953004 chr7:55411919 G/A cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs67311347 0.911 rs9849224 chr3:40392562 T/C cg09455208 chr3:40491958 NA 0.33 6.55 0.33 2.06e-10 Renal cell carcinoma; LIHC cis rs1878931 0.567 rs7196196 chr16:3411855 C/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.85 15.13 0.63 5.92e-40 Body mass index (adult); LIHC cis rs7772486 0.754 rs1415747 chr6:146077249 A/G cg05347473 chr6:146136440 FBXO30 0.37 5.98 0.31 5.51e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7326068 0.524 rs7998500 chr13:21159000 A/G cg27234864 chr13:21295941 IL17D 0.37 5.89 0.3 9.32e-9 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs546131 0.928 rs499183 chr11:34836678 A/G cg06937548 chr11:34938143 PDHX;APIP 0.54 7.49 0.38 5.86e-13 Lung disease severity in cystic fibrosis; LIHC trans rs801193 1.000 rs7785213 chr7:66138978 A/C cg26939375 chr7:64535504 NA -0.42 -6.74 -0.34 6.89e-11 Aortic root size; LIHC cis rs1003719 0.680 rs2835619 chr21:38505380 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.46e-25 Eye color traits; LIHC cis rs1568889 1.000 rs9783375 chr11:28033667 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.74 0.34 6.66e-11 Bipolar disorder; LIHC cis rs736408 0.924 rs2535629 chr3:52833219 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.38 6.26 0.32 1.15e-9 Bipolar disorder; LIHC cis rs2153535 0.580 rs7743995 chr6:8496212 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.81 0.39 6.88e-14 Motion sickness; LIHC cis rs4853012 0.793 rs6723185 chr2:74344884 T/A cg19729930 chr2:74357872 NA 0.8 17.48 0.69 2.36e-49 Gestational age at birth (maternal effect); LIHC cis rs2304069 0.954 rs1469691 chr5:149386716 G/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.97 12.61 0.56 3.25e-30 HIV-1 control; LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg00091569 chr3:40428383 ENTPD3 -0.4 -6.83 -0.35 3.97e-11 Renal cell carcinoma; LIHC cis rs61990749 0.597 rs2364584 chr14:78152286 T/C cg21497246 chr14:78225524 SNW1;C14orf178 0.5 7.74 0.39 1.1e-13 Fibroblast growth factor basic levels; LIHC cis rs2629540 0.889 rs10901808 chr10:126399159 A/C cg08799069 chr10:126477246 METTL10 0.48 7.56 0.38 3.71e-13 Cocaine dependence; LIHC cis rs9814567 1.000 rs6806417 chr3:134211446 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.66 12.37 0.56 2.58e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs244293 0.965 rs2628326 chr17:53178283 T/C cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.54 0.38 4.36e-13 Menarche (age at onset); LIHC cis rs11190604 1.000 rs28522614 chr10:102323141 T/A cg07080220 chr10:102295463 HIF1AN 0.52 7.0 0.35 1.4e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs11212260 0.655 rs11212208 chr11:107278690 C/A cg25435332 chr11:107328525 CWF19L2 0.81 8.77 0.43 8.76e-17 IgG glycosylation; LIHC cis rs10540 1.000 rs61877760 chr11:506596 C/T cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.22e-11 Body mass index; LIHC cis rs3096299 0.933 rs3096297 chr16:89453155 T/G cg02187348 chr16:89574699 SPG7 0.5 7.26 0.37 2.59e-12 Multiple myeloma (IgH translocation); LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.32 -0.32 8.17e-10 Diastolic blood pressure; LIHC cis rs1030268 0.607 rs34218501 chr7:133210375 G/A cg10665199 chr7:133106180 EXOC4 0.48 6.37 0.33 6.2e-10 Intelligence (multi-trait analysis); LIHC cis rs1385374 0.858 rs12298615 chr12:129286756 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.6 7.17 0.36 4.57e-12 Systemic lupus erythematosus; LIHC cis rs7172677 0.768 rs34180494 chr15:75370012 A/C cg09165964 chr15:75287851 SCAMP5 0.48 6.58 0.34 1.74e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs10789491 1.000 rs12794 chr1:47141718 T/C cg15501359 chr1:47185051 KIAA0494 0.76 10.98 0.51 3.13e-24 Response to hepatitis C treatment; LIHC cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg11644478 chr21:40555479 PSMG1 0.83 10.51 0.49 1.38e-22 Cognitive function; LIHC cis rs7909074 1.000 rs4948926 chr10:45392604 G/C cg04218760 chr10:45406644 TMEM72 -0.24 -7.62 -0.38 2.56e-13 Mean corpuscular volume; LIHC cis rs2073300 0.609 rs6137941 chr20:23400848 G/A cg12062639 chr20:23401060 NAPB 1.05 14.07 0.61 8.82e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11098699 0.784 rs11947137 chr4:124205966 C/G cg09941581 chr4:124220074 SPATA5 0.32 6.38 0.33 5.62e-10 Mosquito bite size; LIHC cis rs8072100 0.840 rs1912482 chr17:45454883 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.86 -0.3 1.08e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10791097 0.667 rs4937585 chr11:130741940 A/G cg09137382 chr11:130731461 NA 0.41 6.13 0.31 2.46e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7258465 1.000 rs271624 chr19:18627953 A/G cg10790698 chr19:18539756 SSBP4 -0.34 -7.06 -0.36 9.39e-12 Breast cancer; LIHC cis rs6500602 0.673 rs4786513 chr16:4576423 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.49 7.57 0.38 3.5e-13 Schizophrenia; LIHC cis rs9354352 0.935 rs9345749 chr6:66699892 G/T cg07460842 chr6:66804631 NA -0.55 -8.24 -0.41 3.63e-15 Initial pursuit acceleration in psychotic disorders; LIHC cis rs10256972 0.685 rs10263665 chr7:1110628 A/G cg23978390 chr7:1156363 C7orf50 0.43 6.09 0.31 3.05e-9 Longevity;Endometriosis; LIHC cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg23758822 chr17:41437982 NA 0.94 17.99 0.7 2.25e-51 Menopause (age at onset); LIHC cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg04317338 chr11:64019027 PLCB3 0.85 10.57 0.5 8.9e-23 Mean platelet volume; LIHC cis rs9814567 1.000 rs9869981 chr3:134248801 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs986417 0.818 rs1955702 chr14:61074301 T/A cg27398547 chr14:60952738 C14orf39 0.65 7.25 0.37 2.79e-12 Gut microbiota (bacterial taxa); LIHC cis rs1403694 0.695 rs1523435 chr3:186436306 G/A cg12454167 chr3:186435060 KNG1 0.38 8.73 0.43 1.11e-16 Blood protein levels; LIHC cis rs12479064 0.724 rs28369945 chr2:100080928 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.58 -6.29 -0.32 9.61e-10 Chronic sinus infection; LIHC cis rs6429082 0.608 rs4469707 chr1:235570634 T/C cg26050004 chr1:235667680 B3GALNT2 -0.46 -6.85 -0.35 3.49e-11 Adiposity; LIHC cis rs2228479 0.702 rs11646374 chr16:89857935 G/A cg19635926 chr16:89946313 TCF25 0.55 6.84 0.35 3.57e-11 Skin colour saturation; LIHC trans rs916888 0.610 rs199529 chr17:44837217 A/C cg07870213 chr5:140052090 DND1 0.94 9.82 0.47 3.2e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2251381 0.640 rs2183568 chr21:30484782 A/T cg24692254 chr21:30365293 RNF160 -0.76 -11.65 -0.53 1.17e-26 Selective IgA deficiency; LIHC cis rs4970988 0.527 rs12067556 chr1:150614535 G/A cg18016565 chr1:150552671 MCL1 0.62 12.27 0.55 6.11e-29 Urate levels; LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs8062405 0.755 rs56272201 chr16:28580685 A/G cg07451762 chr16:28383216 NA 0.4 6.99 0.35 1.42e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8103278 1.000 rs9676288 chr19:46292060 G/T cg11657440 chr19:46296263 DMWD -0.53 -8.24 -0.41 3.74e-15 Coronary artery disease; LIHC cis rs11190604 1.000 rs2495737 chr10:102338344 T/C cg07080220 chr10:102295463 HIF1AN 0.54 7.64 0.38 2.27e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg23978390 chr7:1156363 C7orf50 0.54 8.3 0.41 2.52e-15 Longevity;Endometriosis; LIHC cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Bipolar disorder; LIHC cis rs1997103 1.000 rs1997098 chr7:55405594 G/T cg17469321 chr7:55412551 NA 0.48 7.09 0.36 7.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs694739 0.628 rs10897487 chr11:64140704 C/T cg23796481 chr11:64053134 BAD;GPR137 0.46 6.15 0.32 2.11e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs2286503 0.780 rs12113458 chr7:22855628 G/T cg11367502 chr7:22862612 TOMM7 0.46 8.04 0.4 1.49e-14 Fibrinogen; LIHC cis rs10493773 0.775 rs12738010 chr1:86102575 A/C cg17807903 chr1:86174739 ZNHIT6 0.58 10.81 0.5 1.24e-23 Urate levels in overweight individuals; LIHC cis rs7116495 1.000 rs7128317 chr11:71701367 C/T cg26138937 chr11:71823887 C11orf51 0.8 8.03 0.4 1.6e-14 Severe influenza A (H1N1) infection; LIHC cis rs2404602 0.647 rs7181506 chr15:76935677 G/T cg23625390 chr15:77176239 SCAPER 0.51 8.49 0.42 6.6e-16 Blood metabolite levels; LIHC trans rs10242455 0.702 rs45448997 chr7:99041598 G/C cg09045935 chr12:6379348 NA 0.83 6.85 0.35 3.36e-11 Blood metabolite levels; LIHC cis rs17021463 0.676 rs62320932 chr4:95307037 C/T cg11021082 chr4:95130006 SMARCAD1 0.43 7.2 0.36 3.74e-12 Testicular germ cell tumor; LIHC cis rs333960 0.597 rs333966 chr1:110441792 A/G cg09167608 chr1:110449308 NA 0.43 6.02 0.31 4.49e-9 Obesity-related traits; LIHC cis rs6450176 1.000 rs7736354 chr5:53297591 C/T ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs4919694 1.000 rs12257935 chr10:104803062 C/A cg04362960 chr10:104952993 NT5C2 1.14 8.87 0.43 4.02e-17 Arsenic metabolism; LIHC cis rs34779708 0.966 rs34630580 chr10:35449228 A/G cg03585969 chr10:35415529 CREM 0.87 13.09 0.58 4.92e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs8084351 0.577 rs4548946 chr18:50651671 C/T cg24270629 chr18:50823537 DCC -0.44 -6.49 -0.33 3.03e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs910316 0.763 rs13712 chr14:75483812 T/C cg11812906 chr14:75593930 NEK9 0.72 13.68 0.59 2.88e-34 Height; LIHC trans rs66887589 0.592 rs28580295 chr4:120278873 C/T cg25214090 chr10:38739885 LOC399744 0.45 7.49 0.38 5.81e-13 Diastolic blood pressure; LIHC cis rs965469 0.817 rs6515806 chr20:3359138 A/G cg25506879 chr20:3388711 C20orf194 -0.5 -6.12 -0.31 2.51e-9 IFN-related cytopenia; LIHC cis rs11112613 0.775 rs7959699 chr12:105959848 C/A cg03607813 chr12:105948248 NA 0.59 11.03 0.51 2.01e-24 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs208520 0.690 rs12213561 chr6:66705646 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.74 8.52 0.42 5.1e-16 Exhaled nitric oxide output; LIHC cis rs1580019 0.587 rs6972365 chr7:32548931 T/A cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.16 0.44 4.82e-18 Cognitive ability; LIHC cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg18252515 chr7:66147081 NA -1.25 -16.45 -0.66 3.21e-45 Diabetic kidney disease; LIHC cis rs933688 1.000 rs10041402 chr5:90738948 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.82 0.69 1.01e-50 Smoking behavior; LIHC trans rs4718428 0.607 rs66954441 chr7:66369209 T/C cg10756647 chr7:56101905 PSPH 0.64 8.81 0.43 6.36e-17 Corneal structure; LIHC cis rs7412746 0.611 rs1889741 chr1:150869045 T/C cg15448220 chr1:150897856 SETDB1 0.38 6.13 0.31 2.48e-9 Melanoma; LIHC cis rs116248771 0.739 rs73156455 chr3:158367557 A/G cg16708174 chr3:158430962 RARRES1 0.48 6.38 0.33 5.61e-10 diarrhoeal disease at age 2; LIHC cis rs2153535 0.580 rs969422 chr6:8451780 A/T cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19811296 chr10:99161148 RRP12 0.4 6.33 0.32 7.58e-10 Calcium levels; LIHC cis rs12220238 0.915 rs75467340 chr10:75907318 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs66569888 0.754 rs6719028 chr2:106895212 T/C cg16099169 chr2:106886729 NA 0.88 9.25 0.45 2.46e-18 Facial morphology (factor 23); LIHC cis rs9733 0.519 rs7521898 chr1:150707596 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.74 -0.3 2.12e-8 Tonsillectomy; LIHC cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg22633049 chr21:46681294 NA -0.4 -6.91 -0.35 2.41e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs986417 1.000 rs12895784 chr14:60980116 G/T cg27398547 chr14:60952738 C14orf39 0.76 8.46 0.42 8.18e-16 Gut microbiota (bacterial taxa); LIHC trans rs875971 0.545 rs6460281 chr7:65681115 A/C cg26939375 chr7:64535504 NA 0.4 6.39 0.33 5.49e-10 Aortic root size; LIHC cis rs904251 0.504 rs12202664 chr6:37481198 A/G cg08126542 chr6:37504118 NA -0.37 -6.26 -0.32 1.13e-9 Cognitive performance; LIHC cis rs921968 0.648 rs538483 chr2:219458656 T/C cg02985541 chr2:219472218 PLCD4 0.44 8.5 0.42 5.86e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs2635047 0.905 rs7504798 chr18:44610879 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.47 6.13 0.31 2.46e-9 Educational attainment; LIHC cis rs56775891 1.000 rs34945223 chr18:77575871 A/G cg13263691 chr18:77568018 NA 0.24 6.55 0.33 2.09e-10 Schizophrenia; LIHC cis rs317689 0.702 rs544696 chr12:69749939 T/C cg20891283 chr12:69753455 YEATS4 0.83 15.26 0.64 1.82e-40 Response to diuretic therapy; LIHC trans rs11039100 1.000 rs35863965 chr11:5824256 G/T cg11650987 chr12:10280440 CLEC7A 0.4 6.06 0.31 3.5e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs875971 1.000 rs10257427 chr7:65743208 T/C cg11764359 chr7:65958608 NA -0.91 -16.9 -0.67 5.28e-47 Aortic root size; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg27338377 chr3:5068433 NA 0.41 6.37 0.33 5.93e-10 Calcium levels; LIHC cis rs9916302 0.851 rs11657899 chr17:37626963 G/A cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.01e-19 Renal cell carcinoma; LIHC cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg02187348 chr16:89574699 SPG7 0.5 7.49 0.38 5.8e-13 Multiple myeloma (IgH translocation); LIHC cis rs950169 0.922 rs2033284 chr15:84946273 C/T cg17507749 chr15:85114479 UBE2QP1 0.74 8.68 0.42 1.65e-16 Schizophrenia; LIHC cis rs875971 0.862 rs12698521 chr7:65939489 T/C cg11764359 chr7:65958608 NA 0.88 15.8 0.65 1.25e-42 Aortic root size; LIHC cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg23283495 chr1:209979779 IRF6 0.44 7.21 0.36 3.56e-12 Cleft lip with or without cleft palate; LIHC cis rs4555082 0.957 rs3000073 chr14:105729792 G/A cg06808227 chr14:105710500 BRF1 -0.62 -8.74 -0.43 1.08e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg02782426 chr3:40428986 ENTPD3 -0.35 -6.48 -0.33 3.13e-10 Renal cell carcinoma; LIHC cis rs6840360 0.571 rs4696098 chr4:152489053 C/T cg22705602 chr4:152727874 NA -0.34 -6.52 -0.33 2.59e-10 Intelligence (multi-trait analysis); LIHC cis rs17685 0.672 rs1639623 chr7:75707951 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.13 -0.31 2.48e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2933343 1.000 rs1680795 chr3:128620388 T/C cg25356066 chr3:128598488 ACAD9 0.52 6.76 0.34 5.8e-11 IgG glycosylation; LIHC cis rs2075671 0.903 rs62483570 chr7:100300649 C/T cg16850897 chr7:100343110 ZAN -0.41 -5.97 -0.31 5.89e-9 Other erythrocyte phenotypes; LIHC cis rs10792665 0.618 rs7949388 chr11:82656251 A/T cg24227371 chr11:82718527 RAB30 -0.31 -7.11 -0.36 6.78e-12 Obesity-related traits; LIHC cis rs6788895 0.661 rs77431731 chr3:150489911 T/G cg09723797 chr3:150481914 SIAH2 0.81 10.99 0.51 2.93e-24 Breast cancer; LIHC cis rs3749237 0.595 rs10865955 chr3:49499829 G/A cg07636037 chr3:49044803 WDR6 0.56 8.42 0.41 1.03e-15 Resting heart rate; LIHC cis rs9733 0.519 rs1336900 chr1:150679033 C/T cg18016565 chr1:150552671 MCL1 0.55 10.98 0.51 3.21e-24 Tonsillectomy; LIHC cis rs7520050 0.778 rs2991985 chr1:46080530 T/C cg03146154 chr1:46216737 IPP -0.46 -7.6 -0.38 2.82e-13 Red blood cell count;Reticulocyte count; LIHC cis rs6430585 0.583 rs1435577 chr2:136624947 C/G cg07169764 chr2:136633963 MCM6 1.34 23.26 0.78 1.98e-72 Corneal structure; LIHC cis rs7429990 0.932 rs12486714 chr3:48148700 C/G cg11946769 chr3:48343235 NME6 -0.47 -6.24 -0.32 1.28e-9 Educational attainment (years of education); LIHC cis rs7940866 0.903 rs7942900 chr11:130839244 G/A cg12179176 chr11:130786555 SNX19 0.53 7.63 0.38 2.31e-13 Schizophrenia; LIHC trans rs9388451 0.805 rs1028481 chr6:126106573 G/T cg05039488 chr6:79577232 IRAK1BP1 -0.51 -8.15 -0.4 7.17e-15 Brugada syndrome; LIHC cis rs921968 0.541 rs3770214 chr2:219508988 C/T cg02176678 chr2:219576539 TTLL4 -0.57 -7.54 -0.38 4.41e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs34779708 0.931 rs11010101 chr10:35411045 T/A cg03585969 chr10:35415529 CREM 0.87 13.18 0.58 2.31e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1401999 0.898 rs4148564 chr3:183725982 C/T cg01324343 chr3:183735012 ABCC5 0.78 12.94 0.57 1.94e-31 Anterior chamber depth; LIHC cis rs6912958 0.559 rs373646 chr6:88056896 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.34 0.37 1.55e-12 Monocyte percentage of white cells; LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.47 -6.77 -0.34 5.6e-11 Lymphocyte counts; LIHC cis rs2273156 1.000 rs74046408 chr14:35467135 T/C cg16230307 chr14:35515116 FAM177A1 -0.41 -6.05 -0.31 3.88e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs11031096 0.621 rs12282967 chr11:4191477 A/T cg18678763 chr11:4115507 RRM1 -0.41 -5.95 -0.31 6.62e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs8141529 0.748 rs132531 chr22:29297365 C/T cg15103426 chr22:29168792 CCDC117 -0.59 -9.54 -0.46 2.81e-19 Lymphocyte counts; LIHC trans rs970548 0.738 rs61854113 chr10:46004815 C/T cg14222797 chr10:16859974 RSU1 -0.52 -6.08 -0.31 3.25e-9 Total cholesterol levels;Cholesterol, total;HDL cholesterol;HDL cholesterol levels; LIHC cis rs7927592 0.913 rs4084149 chr11:68288567 A/G cg01657329 chr11:68192670 LRP5 -0.46 -5.99 -0.31 5.25e-9 Total body bone mineral density; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg11599414 chr15:65399621 LOC390595 -0.27 -6.52 -0.33 2.6e-10 Calcium levels; LIHC cis rs1707322 0.821 rs10749857 chr1:46248143 C/T cg06784218 chr1:46089804 CCDC17 0.38 6.7 0.34 8.78e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg07308232 chr7:1071921 C7orf50 -0.51 -8.17 -0.4 6.09e-15 Longevity;Endometriosis; LIHC cis rs6598955 0.724 rs4659420 chr1:26614333 G/A cg04990556 chr1:26633338 UBXN11 -0.61 -9.85 -0.47 2.63e-20 Obesity-related traits; LIHC cis rs60871478 1.000 rs6460801 chr7:810506 T/C cg04727924 chr7:799746 HEATR2 -0.58 -8.61 -0.42 2.65e-16 Cerebrospinal P-tau181p levels; LIHC cis rs7208859 0.673 rs36056619 chr17:29172284 T/C cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07176146 chr1:35325364 C1orf212 -0.44 -6.05 -0.31 3.72e-9 Pancreatic cancer; LIHC cis rs589448 0.933 rs2249093 chr12:69753512 G/C cg14784868 chr12:69753453 YEATS4 0.99 23.08 0.78 1.05e-71 Cerebrospinal fluid biomarker levels; LIHC trans rs1814175 0.817 rs1851858 chr11:49855638 G/A cg03929089 chr4:120376271 NA -0.9 -18.31 -0.7 1.15e-52 Height; LIHC cis rs7116495 1.000 rs488799 chr11:71561686 A/G cg26138937 chr11:71823887 C11orf51 0.69 6.7 0.34 8.74e-11 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg08219700 chr8:58056026 NA 0.48 6.41 0.33 4.93e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 0.708 rs35825036 chr7:65986502 T/C cg18252515 chr7:66147081 NA -1.33 -18.17 -0.7 3.94e-52 Diabetic kidney disease; LIHC cis rs7312933 0.607 rs7965392 chr12:42540280 G/A cg01256987 chr12:42539512 GXYLT1 -0.43 -7.06 -0.36 9.46e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg15586393 chr4:1244086 CTBP1;C4orf42 -0.43 -6.04 -0.31 4.07e-9 Longevity; LIHC cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg00149659 chr3:10157352 C3orf10 0.68 7.11 0.36 6.86e-12 Alzheimer's disease; LIHC cis rs9303401 0.704 rs7359501 chr17:56641200 C/T cg12560992 chr17:57184187 TRIM37 0.81 13.13 0.58 3.65e-32 Cognitive test performance; LIHC cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4638749 0.627 rs1522020 chr2:108833346 C/G cg25838818 chr2:108905173 SULT1C2 -0.4 -6.97 -0.35 1.69e-11 Blood pressure; LIHC cis rs61542988 0.570 rs62448267 chr7:22822501 T/C cg11367502 chr7:22862612 TOMM7 0.53 8.68 0.43 1.61e-16 Fibrinogen levels; LIHC cis rs9942416 0.660 rs67803720 chr5:74984408 A/T cg19683494 chr5:74908142 NA 0.58 7.59 0.38 3.05e-13 Age-related disease endophenotypes; LIHC cis rs6547741 0.935 rs4260197 chr2:27794150 C/G cg27432699 chr2:27873401 GPN1 -0.67 -10.86 -0.51 8.12e-24 Oral cavity cancer; LIHC cis rs4555082 0.834 rs11622165 chr14:105759761 C/A cg13114125 chr14:105738426 BRF1 -0.8 -10.07 -0.48 4.54e-21 Mean platelet volume;Platelet distribution width; LIHC trans rs2727020 0.521 rs7114564 chr11:49571231 C/T cg15704280 chr7:45808275 SEPT13 0.81 12.09 0.55 2.84e-28 Coronary artery disease; LIHC cis rs3818285 0.959 rs3740137 chr10:111630917 G/A cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.94 -0.31 7.18e-9 Superior crus of antihelix expression; LIHC cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg03806693 chr22:41940476 POLR3H 1.09 12.91 0.57 2.49e-31 Vitiligo; LIHC cis rs7520050 0.553 rs2993263 chr1:46021630 A/G cg24296786 chr1:45957014 TESK2 -0.46 -6.63 -0.34 1.29e-10 Red blood cell count;Reticulocyte count; LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.59 9.06 0.44 1.02e-17 Height; LIHC cis rs7613875 0.580 rs3774745 chr3:50204745 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.46 -6.79 -0.34 4.9e-11 Body mass index; LIHC cis rs2303745 0.589 rs6512179 chr19:17399105 T/C cg04248312 chr19:17393744 ANKLE1 -0.73 -12.07 -0.55 3.51e-28 Systemic lupus erythematosus; LIHC cis rs12477438 0.834 rs10179043 chr2:99687490 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.52 -0.64 1.77e-41 Chronic sinus infection; LIHC cis rs11098499 0.913 rs67073020 chr4:120152557 C/T cg09307838 chr4:120376055 NA 0.71 10.08 0.48 4.15e-21 Corneal astigmatism; LIHC cis rs2795502 1.000 rs3121279 chr10:43378449 T/A cg20628663 chr10:43360327 NA 0.44 7.02 0.35 1.2e-11 Blood protein levels; LIHC cis rs4319547 0.794 rs61954972 chr12:123074167 T/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.13 -0.36 5.98e-12 Body mass index; LIHC cis rs1023500 0.596 rs133350 chr22:42429049 A/G cg15557168 chr22:42548783 NA -0.44 -6.78 -0.34 5.2e-11 Schizophrenia; LIHC cis rs9905704 0.624 rs11652761 chr17:56986095 C/T cg05425664 chr17:57184151 TRIM37 -0.44 -6.14 -0.31 2.32e-9 Testicular germ cell tumor; LIHC cis rs4466137 0.645 rs6894022 chr5:82982945 T/C cg16102102 chr5:83017553 HAPLN1 -0.54 -8.63 -0.42 2.38e-16 Prostate cancer; LIHC cis rs2153535 0.580 rs2327060 chr6:8447111 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.98 0.4 2.3e-14 Motion sickness; LIHC cis rs929354 0.605 rs7806314 chr7:156946903 A/T cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs932287 0.651 rs1111010 chr11:9049935 A/G cg12365402 chr11:9010492 NRIP3 0.25 5.86 0.3 1.07e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs12824058 0.831 rs11616174 chr12:130814503 A/G cg26677194 chr12:130822605 PIWIL1 0.51 7.17 0.36 4.52e-12 Menopause (age at onset); LIHC cis rs1580019 0.587 rs7806113 chr7:32553084 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.86 0.43 4.49e-17 Cognitive ability; LIHC cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg11764359 chr7:65958608 NA 0.69 9.32 0.45 1.45e-18 Aortic root size; LIHC cis rs7818688 0.697 rs11776186 chr8:95971968 A/G cg16049864 chr8:95962084 TP53INP1 0.57 6.33 0.32 7.64e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs244293 0.931 rs244306 chr17:53237683 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.19 -0.36 4.2e-12 Menarche (age at onset); LIHC cis rs6912958 0.712 rs6454641 chr6:88371060 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.43 -7.71 -0.39 1.34e-13 Monocyte percentage of white cells; LIHC cis rs9828933 0.752 rs13433909 chr3:63948609 C/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.74 -9.51 -0.46 3.38e-19 Type 2 diabetes; LIHC cis rs9534288 0.797 rs9534283 chr13:46589256 C/A cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs6604026 0.740 rs2893225 chr1:93368496 G/C cg17283838 chr1:93427260 FAM69A -0.42 -5.77 -0.3 1.81e-8 Multiple sclerosis; LIHC cis rs9818758 0.556 rs13086240 chr3:49001409 G/A cg07636037 chr3:49044803 WDR6 -0.79 -7.76 -0.39 9.98e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg22963979 chr7:1858916 MAD1L1 -0.43 -7.11 -0.36 6.65e-12 Bipolar disorder and schizophrenia; LIHC cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs11690935 0.885 rs6750058 chr2:172786909 G/T cg13550731 chr2:172543902 DYNC1I2 -0.8 -14.3 -0.61 1.07e-36 Schizophrenia; LIHC cis rs6723226 0.557 rs62136260 chr2:32575447 T/C cg02381751 chr2:32503542 YIPF4 -0.47 -6.25 -0.32 1.19e-9 Intelligence (multi-trait analysis); LIHC cis rs6120849 0.754 rs6088691 chr20:33633758 C/T cg24642439 chr20:33292090 TP53INP2 0.65 7.05 0.36 9.65e-12 Protein C levels; LIHC cis rs896854 0.818 rs896855 chr8:95959808 A/G cg09323728 chr8:95962352 TP53INP1 -0.3 -6.64 -0.34 1.27e-10 Type 2 diabetes; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg00221035 chr7:7222342 C1GALT1 -0.57 -7.09 -0.36 7.55e-12 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6442522 0.644 rs6442528 chr3:15505224 C/G cg16303742 chr3:15540471 COLQ 0.44 7.46 0.37 7.43e-13 Uric acid levels; LIHC trans rs1814175 0.817 rs7946556 chr11:49944874 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs2153535 0.601 rs330105 chr6:8543981 A/C cg07606381 chr6:8435919 SLC35B3 0.78 11.21 0.52 4.79e-25 Motion sickness; LIHC cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7572733 0.534 rs700664 chr2:198671145 C/T cg03934865 chr2:198174659 NA 0.46 6.58 0.34 1.74e-10 Dermatomyositis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15555402 chr12:19593456 AEBP2 0.42 6.17 0.32 1.91e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7224737 0.956 rs8081327 chr17:40274200 G/A cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs9814567 1.000 rs9814567 chr3:134218557 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.21 0.55 1.05e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9916302 0.904 rs4795355 chr17:37427382 C/T cg03013999 chr17:37608204 MED1 0.36 6.07 0.31 3.41e-9 Glomerular filtration rate (creatinine); LIHC cis rs928736 0.599 rs1000005 chr21:34433051 C/G cg00274965 chr21:34405681 NA 0.33 5.85 0.3 1.17e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC trans rs2579103 0.767 rs2118804 chr12:90665966 C/T cg00091569 chr3:40428383 ENTPD3 0.37 6.05 0.31 3.8e-9 Body mass index; LIHC cis rs12464559 0.522 rs4300824 chr2:152581866 T/C cg01189475 chr2:152685088 ARL5A 0.72 9.02 0.44 1.41e-17 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs2932538 0.961 rs10745332 chr1:113189053 G/A cg22162597 chr1:113214053 CAPZA1 -0.73 -11.2 -0.52 5.15e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs4423214 0.592 rs10898193 chr11:71197083 A/G cg05163923 chr11:71159392 DHCR7 0.59 7.39 0.37 1.11e-12 Vitamin D levels; LIHC cis rs6912958 0.514 rs7767449 chr6:87887985 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.57 -10.48 -0.49 1.83e-22 Monocyte percentage of white cells; LIHC cis rs1568889 0.838 rs11030187 chr11:28044391 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 13.89 0.6 4.42e-35 Bipolar disorder; LIHC cis rs4555082 0.834 rs2975217 chr14:105710238 A/C cg06808227 chr14:105710500 BRF1 -0.53 -6.95 -0.35 1.84e-11 Mean platelet volume;Platelet distribution width; LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg00280220 chr17:61926910 NA 0.43 7.05 0.36 1.03e-11 Prudent dietary pattern; LIHC trans rs10411161 0.702 rs1433081 chr19:52390710 A/C cg22319618 chr22:45562946 NUP50 -0.63 -8.59 -0.42 3.15e-16 Breast cancer; LIHC cis rs9393692 0.905 rs9379838 chr6:26277133 C/T cg13736514 chr6:26305472 NA -0.37 -6.23 -0.32 1.34e-9 Educational attainment; LIHC cis rs1023500 0.573 rs133382 chr22:42471774 C/T cg00645731 chr22:42541494 CYP2D7P1 0.39 6.23 0.32 1.37e-9 Schizophrenia; LIHC trans rs2727020 0.521 rs11040377 chr11:49474346 T/C cg03929089 chr4:120376271 NA -0.53 -8.56 -0.42 3.94e-16 Coronary artery disease; LIHC cis rs28453840 1 rs28453840 chr2:136522941 G/A cg07169764 chr2:136633963 MCM6 -0.68 -9.77 -0.47 4.87e-20 Cholesterol, total; LIHC cis rs2204008 0.837 rs7308714 chr12:38274307 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.57e-21 Bladder cancer; LIHC cis rs875971 1.000 rs7792762 chr7:66004138 T/C cg18252515 chr7:66147081 NA -0.44 -6.38 -0.33 5.78e-10 Aortic root size; LIHC cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg17971929 chr21:40555470 PSMG1 -0.46 -6.85 -0.35 3.46e-11 Cognitive function; LIHC cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg08888203 chr3:10149979 C3orf24 0.56 6.8 0.35 4.62e-11 Alzheimer's disease; LIHC cis rs2404602 0.735 rs1607015 chr15:76702429 C/T cg23625390 chr15:77176239 SCAPER -0.48 -7.91 -0.39 3.7e-14 Blood metabolite levels; LIHC cis rs3806843 0.966 rs2563265 chr5:140137005 C/T cg19875535 chr5:140030758 IK -0.37 -6.14 -0.32 2.31e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs1814175 0.616 rs1794131 chr11:49904194 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs1059312 0.808 rs12831705 chr12:129294905 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.78 -17.13 -0.68 6.09e-48 Systemic lupus erythematosus; LIHC cis rs6964587 0.692 rs4729021 chr7:91758422 C/A cg17063962 chr7:91808500 NA 0.64 11.4 0.52 9.44e-26 Breast cancer; LIHC cis rs17685 0.753 rs2302435 chr7:75676987 G/A cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.09 0.31 2.99e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs700651 0.821 rs700690 chr2:198727626 A/G cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Intracranial aneurysm; LIHC cis rs12497850 0.931 rs10780033 chr3:48891275 T/C cg07636037 chr3:49044803 WDR6 0.93 16.94 0.68 3.74e-47 Parkinson's disease; LIHC cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs782590 0.764 rs2054728 chr2:55818419 C/T cg03859395 chr2:55845619 SMEK2 0.73 11.77 0.54 4.47e-27 Metabolic syndrome; LIHC cis rs8081395 0.711 rs11368 chr17:58031412 A/G cg13753209 chr17:57696993 CLTC 0.39 5.93 0.31 7.57e-9 White blood cell count; LIHC trans rs916888 0.738 rs199515 chr17:44856641 C/G cg22968622 chr17:43663579 NA -1.09 -12.74 -0.57 1.09e-30 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs17106184 1.000 rs9701805 chr1:51356810 G/C cg07174182 chr1:51127561 FAF1 -0.74 -8.05 -0.4 1.35e-14 Type 2 diabetes; LIHC cis rs9325144 0.600 rs6582634 chr12:38748041 G/A cg26384229 chr12:38710491 ALG10B 0.57 7.84 0.39 5.77e-14 Morning vs. evening chronotype; LIHC cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg12373951 chr3:133503437 NA 0.76 14.49 0.62 1.96e-37 Iron status biomarkers; LIHC cis rs6545883 0.931 rs9807965 chr2:61732159 T/C cg14146966 chr2:61757674 XPO1 0.49 8.62 0.42 2.6e-16 Tuberculosis; LIHC cis rs17345786 0.906 rs72940399 chr3:101122575 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.56 7.05 0.36 1e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs202629 1 rs202629 chr22:41849975 C/T cg06481639 chr22:41940642 POLR3H 0.69 7.17 0.36 4.64e-12 Cannabis dependence symptom count; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg16132339 chr22:24313637 DDTL;DDT 0.66 11.64 0.53 1.31e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg09417038 chr21:47716443 C21orf57 -0.54 -8.04 -0.4 1.45e-14 Testicular germ cell tumor; LIHC trans rs1005277 0.579 rs2474568 chr10:38383147 A/T cg27523141 chr10:43048294 ZNF37B 0.36 6.2 0.32 1.62e-9 Extrinsic epigenetic age acceleration; LIHC cis rs798554 0.836 rs798500 chr7:2790685 C/T cg19717773 chr7:2847554 GNA12 0.41 6.56 0.33 1.97e-10 Height; LIHC cis rs870825 0.616 rs12502860 chr4:185636105 T/C cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg02869306 chr7:64672164 INTS4L1 -0.3 -6.62 -0.34 1.37e-10 Calcium levels; LIHC cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg06453172 chr10:134556979 INPP5A -0.63 -7.94 -0.39 2.98e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3892630 0.817 rs35408716 chr19:33187961 A/C cg22980127 chr19:33182716 NUDT19 1.04 12.43 0.56 1.53e-29 Red blood cell traits; LIHC cis rs10504229 0.953 rs59034808 chr8:58185337 T/C cg02290350 chr8:58132656 NA 0.41 8.7 0.43 1.43e-16 Developmental language disorder (linguistic errors); LIHC cis rs4906332 1.000 rs12896612 chr14:103877868 A/G cg19000871 chr14:103996768 TRMT61A -0.45 -7.77 -0.39 9.55e-14 Coronary artery disease; LIHC cis rs7829975 0.514 rs2976929 chr8:8258712 T/C cg15556689 chr8:8085844 FLJ10661 0.41 6.67 0.34 1.02e-10 Mood instability; LIHC cis rs17826219 0.636 rs8080829 chr17:29058730 C/T cg13385521 chr17:29058706 SUZ12P 0.84 8.38 0.41 1.44e-15 Body mass index; LIHC cis rs67981189 0.593 rs2251394 chr14:71436074 A/G cg15816911 chr14:71606274 NA -0.4 -6.42 -0.33 4.59e-10 Schizophrenia; LIHC cis rs7772486 0.875 rs854146 chr6:146341033 A/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.36 -0.33 6.29e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs5753618 0.561 rs2078803 chr22:31652852 G/A cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC trans rs116095464 0.558 rs6875291 chr5:264192 T/C cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs6466055 0.720 rs3801999 chr7:105027646 G/A cg04380332 chr7:105027541 SRPK2 0.36 6.76 0.34 5.87e-11 Schizophrenia; LIHC cis rs7772486 0.754 rs702306 chr6:145991029 T/C cg13319975 chr6:146136371 FBXO30 0.39 6.27 0.32 1.1e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs826838 0.616 rs1601746 chr12:38626195 G/T cg26384229 chr12:38710491 ALG10B -0.42 -6.39 -0.33 5.44e-10 Heart rate; LIHC cis rs7727544 0.660 rs272886 chr5:131665840 T/C cg24060327 chr5:131705240 SLC22A5 -0.59 -8.54 -0.42 4.41e-16 Blood metabolite levels; LIHC cis rs1555399 1.000 rs1555399 chr14:67984370 T/A cg16224230 chr14:67978224 TMEM229B -0.24 -5.76 -0.3 1.85e-8 Parkinson's disease; LIHC cis rs3815308 0.530 rs12973409 chr19:2196963 A/G cg09261902 chr19:2140048 AP3D1 0.35 6.05 0.31 3.9e-9 Breast cancer; LIHC cis rs2576037 0.526 rs2156050 chr18:44455873 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.73e-12 Personality dimensions; LIHC cis rs12908161 0.853 rs12912342 chr15:85248216 T/C cg17507749 chr15:85114479 UBE2QP1 0.49 5.8 0.3 1.55e-8 Schizophrenia; LIHC cis rs597539 0.652 rs514833 chr11:68657734 C/T cg06028808 chr11:68637592 NA 0.44 5.78 0.3 1.7e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs10751667 0.643 rs11246344 chr11:933783 A/C cg06064525 chr11:970664 AP2A2 -0.55 -14.76 -0.62 1.8e-38 Alzheimer's disease (late onset); LIHC cis rs2439831 0.867 rs16957630 chr15:43642780 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs10744422 1.000 rs4759381 chr12:123348480 G/A cg22842854 chr12:123319900 HIP1R -0.72 -9.02 -0.44 1.39e-17 Schizophrenia; LIHC trans rs6489882 0.867 rs6489869 chr12:113363922 A/C cg10175203 chr3:128143634 NA 0.39 6.39 0.33 5.57e-10 Chronic lymphocytic leukemia; LIHC cis rs2016586 0.543 rs5755906 chr22:36096091 T/C cg26342177 chr22:36113512 APOL5 -0.36 -5.93 -0.31 7.46e-9 Body mass index; LIHC cis rs8062405 1.000 rs62037365 chr16:28868962 C/G cg07451762 chr16:28383216 NA 0.31 5.96 0.31 6.17e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2845885 0.793 rs3751120 chr11:63884453 C/T cg05555928 chr11:63887634 MACROD1 -0.5 -7.02 -0.36 1.17e-11 Body mass index; LIHC cis rs67478160 0.595 rs67768834 chr14:104221085 C/G cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.61 -0.38 2.66e-13 Schizophrenia; LIHC cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg06481639 chr22:41940642 POLR3H -0.62 -5.93 -0.31 7.49e-9 Vitiligo; LIHC cis rs6840360 1.000 rs7669977 chr4:152677527 T/C cg22705602 chr4:152727874 NA -0.34 -7.15 -0.36 5.42e-12 Intelligence (multi-trait analysis); LIHC cis rs3015497 0.653 rs2356455 chr14:51093142 G/A cg09863266 chr14:51125203 SAV1 -0.39 -6.16 -0.32 2.03e-9 Mean platelet volume; LIHC cis rs2295359 1.000 rs2295359 chr1:67635950 G/A cg12940439 chr1:67600707 NA 0.37 6.48 0.33 3.16e-10 Psoriasis; LIHC cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg11764359 chr7:65958608 NA -0.57 -5.89 -0.3 9.17e-9 Diabetic kidney disease; LIHC cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg11062466 chr8:58055876 NA 0.48 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18043075 chr10:115933939 MIR2110;C10orf118 -0.43 -6.07 -0.31 3.33e-9 Pancreatic cancer; LIHC cis rs6977660 0.714 rs4719586 chr7:19825548 T/C cg07541023 chr7:19748670 TWISTNB 0.42 6.13 0.31 2.42e-9 Thyroid stimulating hormone; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -6.97 -0.35 1.59e-11 Total body bone mineral density; LIHC cis rs55882075 0.723 rs56227602 chr5:179179472 A/G cg14593053 chr5:179126677 CANX 0.45 8.04 0.4 1.49e-14 Monocyte percentage of white cells; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg04161413 chr2:99225218 C2orf64;UNC50 -0.39 -6.11 -0.31 2.74e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs10463316 0.780 rs6894899 chr5:150775913 C/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.54 -0.33 2.23e-10 Metabolite levels (Pyroglutamine); LIHC cis rs17685 0.784 rs1613890 chr7:75735037 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.17 -0.32 1.97e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs62064224 0.902 rs17732573 chr17:30627664 C/T cg18200150 chr17:30822561 MYO1D -0.49 -8.66 -0.42 1.91e-16 Schizophrenia; LIHC cis rs3859192 0.599 rs12451897 chr17:38179275 G/T cg17467752 chr17:38218738 THRA -0.5 -8.76 -0.43 9.11e-17 White blood cell count; LIHC cis rs8180040 0.903 rs2276854 chr3:47276968 C/T cg27129171 chr3:47204927 SETD2 0.69 11.98 0.54 7.23e-28 Colorectal cancer; LIHC cis rs6665290 0.868 rs2183836 chr1:227199404 A/T cg10327440 chr1:227177885 CDC42BPA -1.2 -29.5 -0.85 5.6e-96 Myeloid white cell count; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg17918875 chr8:17780190 PCM1 -0.38 -6.33 -0.32 7.56e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs763014 0.932 rs2269559 chr16:682297 T/C cg04709771 chr16:646395 RAB40C 0.46 8.26 0.41 3.16e-15 Height; LIHC cis rs77861329 1.000 rs9809254 chr3:52111474 T/C cg08692210 chr3:52188851 WDR51A 0.83 8.32 0.41 2.05e-15 Macrophage inflammatory protein 1b levels; LIHC cis rs7927592 0.956 rs10896343 chr11:68317860 G/C cg01657329 chr11:68192670 LRP5 -0.46 -6.06 -0.31 3.66e-9 Total body bone mineral density; LIHC cis rs798554 0.679 rs11973498 chr7:2886873 C/A cg04166393 chr7:2884313 GNA12 0.52 8.36 0.41 1.57e-15 Height; LIHC cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg11062466 chr8:58055876 NA 0.43 5.77 0.3 1.8e-8 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg00750074 chr16:89608354 SPG7 -0.54 -8.81 -0.43 6.63e-17 Multiple myeloma (IgH translocation); LIHC cis rs2842992 0.872 rs9456440 chr6:160074463 G/T cg19482086 chr6:160211437 TCP1;MRPL18 0.69 11.53 0.53 3.38e-26 Age-related macular degeneration (geographic atrophy); LIHC cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg04025307 chr7:1156635 C7orf50 0.56 9.04 0.44 1.18e-17 Longevity;Endometriosis; LIHC cis rs7772486 0.754 rs702324 chr6:146008793 A/G cg13319975 chr6:146136371 FBXO30 0.39 5.73 0.3 2.17e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4294134 1.000 rs10234309 chr7:135311167 G/A cg20392616 chr7:135392013 SLC13A4 -0.41 -6.72 -0.34 7.52e-11 Paget's disease; LIHC cis rs7412746 0.611 rs7532045 chr1:150821847 G/A cg18016565 chr1:150552671 MCL1 0.52 9.73 0.47 6.77e-20 Melanoma; LIHC cis rs9858542 1.000 rs1131095 chr3:49714225 T/C cg03060546 chr3:49711283 APEH -0.62 -8.52 -0.42 5.26e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19478983 chr7:120590592 ING3 -0.51 -6.48 -0.33 3.15e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6570726 0.791 rs7765687 chr6:145915100 A/C cg23711669 chr6:146136114 FBXO30 0.63 10.48 0.49 1.77e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg06873352 chr17:61820015 STRADA -0.68 -11.73 -0.54 5.98e-27 Prudent dietary pattern; LIHC cis rs4319547 0.737 rs7964138 chr12:122950375 A/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.37 -0.37 1.25e-12 Body mass index; LIHC cis rs2066819 1.000 rs2306693 chr12:56680531 T/C cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs67478160 0.643 rs6575997 chr14:104228546 C/T cg01849466 chr14:104193079 ZFYVE21 0.49 8.03 0.4 1.54e-14 Schizophrenia; LIHC cis rs7904368 0.806 rs6602161 chr10:16862280 A/G cg14835575 chr10:16859367 RSU1 0.68 9.51 0.46 3.46e-19 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs370915 0.564 rs10027461 chr4:187837608 T/C cg19519643 chr4:187840862 NA -0.54 -9.36 -0.45 1.06e-18 Gout; LIHC cis rs74181299 0.750 rs58342673 chr2:65347584 T/C cg05010058 chr2:65284262 CEP68 -0.39 -6.42 -0.33 4.56e-10 Pulse pressure; LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg13409248 chr3:40428643 ENTPD3 0.49 8.27 0.41 3.08e-15 Renal cell carcinoma; LIHC cis rs5769707 0.706 rs2071903 chr22:50034517 G/A cg07959070 chr22:50026188 C22orf34 -0.35 -8.56 -0.42 3.79e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7091068 0.671 rs1096025 chr10:95404701 T/C cg20715218 chr10:95462985 C10orf4 -0.63 -7.05 -0.36 9.84e-12 Urinary tract infection frequency; LIHC cis rs4700695 0.841 rs706681 chr5:65317913 G/T cg21114390 chr5:65439923 SFRS12 0.45 5.71 0.3 2.4e-8 Facial morphology (factor 19); LIHC cis rs2932538 0.922 rs12048528 chr1:113210534 A/C cg22162597 chr1:113214053 CAPZA1 -0.73 -11.15 -0.52 7.69e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs66887589 0.870 rs2389875 chr4:120557014 G/T cg25214090 chr10:38739885 LOC399744 -0.38 -6.06 -0.31 3.62e-9 Diastolic blood pressure; LIHC cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.43 0.37 8.56e-13 Bipolar disorder; LIHC cis rs7100689 0.556 rs6585971 chr10:82145057 G/C cg01528321 chr10:82214614 TSPAN14 0.85 12.01 0.54 5.59e-28 Post bronchodilator FEV1; LIHC cis rs1577917 0.785 rs1885607 chr6:86394905 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.67 12.89 0.57 2.92e-31 Response to antipsychotic treatment; LIHC cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg15857475 chr8:145742913 RECQL4;LRRC14 -0.63 -10.29 -0.49 8.04e-22 Age at first birth; LIHC cis rs6582630 0.519 rs8189549 chr12:38245752 A/G cg26384229 chr12:38710491 ALG10B 0.87 10.83 0.51 1.06e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg14393609 chr7:65229607 NA 0.44 6.55 0.33 2.08e-10 Aortic root size; LIHC cis rs12477438 0.520 rs13010904 chr2:99754289 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.62 0.62 5.83e-38 Chronic sinus infection; LIHC cis rs35146811 0.807 rs6465761 chr7:99620277 G/C cg22906224 chr7:99728672 NA 0.44 6.29 0.32 9.67e-10 Coronary artery disease; LIHC cis rs36051895 0.632 rs12337480 chr9:5134567 T/A cg02405213 chr9:5042618 JAK2 -0.67 -11.52 -0.53 3.53e-26 Pediatric autoimmune diseases; LIHC cis rs11098499 0.908 rs71614449 chr4:120387055 C/T cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs4891159 0.790 rs77878087 chr18:74116337 G/A cg24786174 chr18:74118243 ZNF516 -0.79 -14.35 -0.61 6.91e-37 Longevity; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16217313 chr6:107077344 RTN4IP1;QRSL1 -0.54 -6.28 -0.32 1.01e-9 Systolic blood pressure; LIHC cis rs797680 0.856 rs7512911 chr1:93715818 C/G cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.89 0.3 9.29e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs8180040 0.764 rs11130115 chr3:47181661 C/A cg27129171 chr3:47204927 SETD2 0.69 12.1 0.55 2.64e-28 Colorectal cancer; LIHC cis rs6762 0.642 rs28692469 chr11:839675 T/C cg15787769 chr11:842744 TSPAN4;POLR2L -0.62 -7.55 -0.38 3.97e-13 Mean platelet volume; LIHC cis rs12464483 0.524 rs1901906 chr2:30884576 A/G cg12454169 chr2:30669597 LCLAT1 -0.43 -5.77 -0.3 1.79e-8 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs35306767 0.903 rs34270014 chr10:904666 T/C cg26597838 chr10:835615 NA 1.17 13.75 0.6 1.47e-34 Eosinophil percentage of granulocytes; LIHC cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg13047869 chr3:10149882 C3orf24 0.48 5.96 0.31 6.31e-9 Alzheimer's disease; LIHC cis rs1823913 1.000 rs1840377 chr2:192122718 T/C cg12404831 chr2:192114017 MYO1B -0.32 -6.54 -0.33 2.21e-10 Obesity-related traits; LIHC cis rs9902453 0.967 rs55744550 chr17:28475729 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.41 0.45 7.5e-19 Coffee consumption (cups per day); LIHC cis rs921968 0.509 rs626432 chr2:219355658 C/A cg02985541 chr2:219472218 PLCD4 0.42 6.92 0.35 2.24e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7216064 1.000 rs58551145 chr17:65837235 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.34 -0.45 1.26e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6960043 0.818 rs10238625 chr7:15054232 A/G cg19272540 chr7:15055459 NA 0.26 7.06 0.36 9.39e-12 Type 2 diabetes; LIHC cis rs6754311 0.628 rs309811 chr2:136625602 A/G cg07169764 chr2:136633963 MCM6 -0.67 -10.09 -0.48 4.07e-21 Mosquito bite size; LIHC cis rs589448 0.902 rs2603089 chr12:69776800 C/T cg19645103 chr12:69753606 YEATS4 0.4 5.99 0.31 5.19e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs921968 0.541 rs41461846 chr2:219313354 A/G cg02985541 chr2:219472218 PLCD4 -0.43 -7.02 -0.35 1.19e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2115630 1.000 rs6496441 chr15:85363348 A/G cg12501888 chr15:85177176 SCAND2 -0.47 -7.19 -0.36 4e-12 P wave terminal force; LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg11494091 chr17:61959527 GH2 -0.54 -10.61 -0.5 6.17e-23 Prudent dietary pattern; LIHC trans rs800082 0.934 rs6788831 chr3:144290498 G/T cg24215973 chr2:240111563 HDAC4 -0.49 -7.1 -0.36 7.23e-12 Smoking behavior; LIHC cis rs858239 0.896 rs1637192 chr7:23260514 G/A cg18081818 chr7:23246105 NA -0.42 -6.26 -0.32 1.14e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2540917 0.631 rs12104736 chr2:60650716 C/G cg00543073 chr2:60773386 BCL11A -0.32 -6.4 -0.33 5.21e-10 Mean corpuscular volume; LIHC trans rs9914544 0.545 rs1037037 chr17:18765021 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.8e-10 Educational attainment (years of education); LIHC cis rs11190604 1.000 rs11190597 chr10:102293676 A/T cg07080220 chr10:102295463 HIF1AN 0.57 8.12 0.4 8.77e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.22 0.32 1.43e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2273669 0.667 rs112319185 chr6:109305318 T/C cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs3806843 0.735 rs778596 chr5:140037272 G/A cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg12016809 chr21:47604291 C21orf56 0.48 7.48 0.37 6.43e-13 Testicular germ cell tumor; LIHC cis rs7927771 0.864 rs11600581 chr11:47448497 T/C cg20135002 chr11:47629003 NA -0.56 -9.52 -0.46 3.25e-19 Subjective well-being; LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.35 -0.32 6.81e-10 Total body bone mineral density; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01008834 chr1:150207620 ANP32E 0.51 6.57 0.33 1.86e-10 Lung function (FEV1/FVC); LIHC cis rs2933343 0.621 rs789242 chr3:128585707 T/C cg25356066 chr3:128598488 ACAD9 0.56 7.65 0.38 2.06e-13 IgG glycosylation; LIHC cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg16497277 chr3:49208875 KLHDC8B -0.49 -6.2 -0.32 1.66e-9 Menarche (age at onset); LIHC cis rs7582180 0.629 rs11685406 chr2:100946638 A/G cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.97e-16 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg18230493 chr5:56204884 C5orf35 -0.47 -6.48 -0.33 3.28e-10 Initial pursuit acceleration; LIHC cis rs10779751 0.959 rs2092642 chr1:11317320 C/T cg08854313 chr1:11322531 MTOR 0.87 15.77 0.65 1.66e-42 Body mass index; LIHC trans rs763512 0.532 rs1416 chr17:35894811 T/C cg21037784 chr14:101351511 RTL1 -0.27 -6.08 -0.31 3.22e-9 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg21724239 chr8:58056113 NA 0.47 6.24 0.32 1.32e-9 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.579 rs2749616 chr10:38510993 A/T cg17219203 chr10:38645113 HSD17B7P2 -0.4 -5.83 -0.3 1.26e-8 Extrinsic epigenetic age acceleration; LIHC cis rs2274273 0.870 rs66696758 chr14:55766509 G/A cg01864836 chr14:55583639 NA -0.37 -6.63 -0.34 1.35e-10 Protein biomarker; LIHC cis rs9486719 1.000 rs11152951 chr6:96894135 C/G cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs10504229 0.610 rs7011877 chr8:58147181 C/T cg20607798 chr8:58055168 NA 0.51 6.37 0.33 5.93e-10 Developmental language disorder (linguistic errors); LIHC cis rs4803468 1.000 rs10422783 chr19:41906436 T/C cg14132834 chr19:41945861 ATP5SL -0.43 -6.46 -0.33 3.56e-10 Height; LIHC cis rs9902453 0.765 rs2628180 chr17:28101723 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC trans rs1814175 0.817 rs7946556 chr11:49944874 G/A cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs921968 0.509 rs655441 chr2:219357545 C/T cg02176678 chr2:219576539 TTLL4 0.52 7.09 0.36 7.61e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs9303401 0.527 rs12946522 chr17:56768103 A/C cg25039879 chr17:56429692 SUPT4H1 0.74 8.03 0.4 1.62e-14 Cognitive test performance; LIHC cis rs6963495 0.745 rs73192151 chr7:105211876 A/G cg19920283 chr7:105172520 RINT1 0.66 6.02 0.31 4.39e-9 Bipolar disorder (body mass index interaction); LIHC trans rs1945213 0.694 rs9888298 chr11:55865704 T/C cg03929089 chr4:120376271 NA 0.54 6.86 0.35 3.33e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs11098699 0.821 rs17006775 chr4:124214850 A/G cg09941581 chr4:124220074 SPATA5 -0.35 -7.16 -0.36 4.96e-12 Mosquito bite size; LIHC cis rs72781680 0.752 rs72780185 chr2:24003967 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs2257205 0.667 rs7342841 chr17:56916156 G/A cg12560992 chr17:57184187 TRIM37 0.67 7.22 0.36 3.29e-12 Pancreatic cancer; LIHC cis rs3741151 0.881 rs73542929 chr11:73094539 G/T cg17517138 chr11:73019481 ARHGEF17 0.86 6.16 0.32 2e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs703842 0.560 rs11533604 chr12:58047713 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.54 7.35 0.37 1.47e-12 Multiple sclerosis; LIHC cis rs873946 0.586 rs11146503 chr10:134565388 T/C cg27297192 chr10:134578999 INPP5A 0.52 7.1 0.36 7.07e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13470557 chr20:61431876 C20orf20 0.42 6.11 0.31 2.69e-9 Hepatitis; LIHC cis rs5769765 0.908 rs4058453 chr22:50250297 T/C cg02269571 chr22:50332266 NA 0.74 8.22 0.41 4.23e-15 Schizophrenia; LIHC cis rs6456156 0.586 rs12203510 chr6:167473006 C/T cg23791538 chr6:167370224 RNASET2 -0.52 -8.51 -0.42 5.65e-16 Primary biliary cholangitis; LIHC trans rs2727020 0.575 rs10769587 chr11:49549849 C/G cg15704280 chr7:45808275 SEPT13 -0.98 -20.13 -0.74 5.24e-60 Coronary artery disease; LIHC cis rs11958404 0.929 rs80162289 chr5:157354639 T/C cg05962755 chr5:157440814 NA 0.97 9.4 0.45 7.84e-19 IgG glycosylation; LIHC cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg05590025 chr7:65112418 INTS4L2 0.66 7.39 0.37 1.12e-12 Diabetic kidney disease; LIHC cis rs7258465 1.000 rs10403249 chr19:18604942 T/C cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC cis rs8060686 0.546 rs8047343 chr16:68143745 G/A cg05110241 chr16:68378359 PRMT7 -0.48 -5.83 -0.3 1.27e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs963731 0.649 rs212322 chr2:39305928 C/T cg04010122 chr2:39346883 SOS1 -0.61 -6.18 -0.32 1.82e-9 Corticobasal degeneration; LIHC cis rs2380220 0.808 rs2613551 chr6:95914740 G/A cg04719120 chr6:96025338 MANEA -0.58 -6.24 -0.32 1.33e-9 Behavioural disinhibition (generation interaction); LIHC trans rs2019216 0.605 rs11654492 chr17:22008649 A/C cg14296220 chr9:32431791 ACO1 0.39 6.28 0.32 1.01e-9 Pelvic organ prolapse; LIHC cis rs1005277 0.579 rs2103938 chr10:38493998 T/G cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.2 -0.32 1.66e-9 Extrinsic epigenetic age acceleration; LIHC trans rs2096176 0.606 rs1339813 chr10:26313980 G/A cg01396774 chr2:218299024 DIRC3 -0.31 -6.09 -0.31 3.07e-9 Obesity-related traits; LIHC cis rs6459788 0.605 rs887628 chr7:157237589 G/A cg06271696 chr7:157225062 NA -0.48 -7.75 -0.39 1.04e-13 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs11626933 1.000 rs61989986 chr14:90739180 G/A cg04374321 chr14:90722782 PSMC1 0.48 6.57 0.33 1.91e-10 Gut microbiota (bacterial taxa); LIHC trans rs911555 0.723 rs6575986 chr14:103886671 G/A cg17675199 chr6:35436792 RPL10A 0.39 8.01 0.4 1.87e-14 Intelligence (multi-trait analysis); LIHC trans rs11039798 0.588 rs11039781 chr11:48523085 T/G cg15704280 chr7:45808275 SEPT13 0.57 6.32 0.32 8.19e-10 Axial length; LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg18306943 chr3:40428807 ENTPD3 0.4 7.05 0.36 9.77e-12 Renal cell carcinoma; LIHC cis rs9733 0.596 rs72702585 chr1:150696427 G/A cg18016565 chr1:150552671 MCL1 0.57 11.31 0.52 2.16e-25 Tonsillectomy; LIHC cis rs8027181 0.958 rs4776614 chr15:73082468 C/G cg25632853 chr15:73088954 NA 0.39 6.34 0.32 7.1e-10 Triglyceride levels; LIHC cis rs1707322 1.000 rs1768801 chr1:46549137 C/G cg03146154 chr1:46216737 IPP -0.45 -7.27 -0.37 2.52e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1997103 0.822 rs10273426 chr7:55417857 G/A cg17469321 chr7:55412551 NA 0.51 7.34 0.37 1.58e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg06481639 chr22:41940642 POLR3H 0.71 7.06 0.36 9.26e-12 Vitiligo; LIHC trans rs11098499 0.821 rs3775852 chr4:120454556 A/G cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg16606324 chr3:10149918 C3orf24 0.54 5.81 0.3 1.4e-8 Alzheimer's disease; LIHC cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg11764359 chr7:65958608 NA -0.57 -5.95 -0.31 6.77e-9 Diabetic kidney disease; LIHC cis rs909341 0.909 rs67616625 chr20:62363487 A/G cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.74e-11 Atopic dermatitis; LIHC cis rs2295359 0.892 rs10789224 chr1:67605134 C/T cg08029281 chr1:67600428 NA -0.35 -6.05 -0.31 3.84e-9 Psoriasis; LIHC cis rs11711311 1.000 rs9826465 chr3:113432254 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.47 -0.37 6.67e-13 IgG glycosylation; LIHC cis rs6424115 0.867 rs34902309 chr1:24192200 A/G cg10978503 chr1:24200527 CNR2 -0.35 -8.43 -0.41 1.01e-15 Immature fraction of reticulocytes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00930347 chr6:110012366 AKD1;FIG4 0.48 7.02 0.35 1.19e-11 Cognitive function; LIHC cis rs472402 0.580 rs6884552 chr5:6661966 C/T cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.48 -6.12 -0.31 2.5e-9 Response to amphetamines; LIHC cis rs965469 0.779 rs6051717 chr20:3270242 C/T cg25506879 chr20:3388711 C20orf194 -0.53 -6.5 -0.33 2.85e-10 IFN-related cytopenia; LIHC cis rs7843479 0.601 rs10109521 chr8:21829948 G/A cg17168535 chr8:21777572 XPO7 0.58 10.04 0.48 5.89e-21 Mean corpuscular volume; LIHC cis rs6662572 0.853 rs2065708 chr1:45977685 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.6 6.38 0.33 5.74e-10 Blood protein levels; LIHC cis rs2153535 0.504 rs9328472 chr6:8470848 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26476595 chr16:2284284 E4F1 0.43 6.52 0.33 2.53e-10 Pancreatic cancer; LIHC cis rs875971 0.545 rs67397473 chr7:65633305 A/G cg11764359 chr7:65958608 NA 0.51 7.0 0.35 1.34e-11 Aortic root size; LIHC cis rs6840360 0.533 rs13145446 chr4:152729035 G/A cg22705602 chr4:152727874 NA 0.36 7.6 0.38 2.95e-13 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.913 rs4316515 chr11:68308840 A/T cg20283391 chr11:68216788 NA 0.53 7.86 0.39 4.91e-14 Total body bone mineral density; LIHC cis rs10883723 0.810 rs7069356 chr10:104254359 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2749592 0.531 rs1208559 chr10:38221370 T/C cg00409905 chr10:38381863 ZNF37A 0.52 9.01 0.44 1.45e-17 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6456156 0.586 rs911632 chr6:167471461 T/C cg07741184 chr6:167504864 NA 0.29 6.86 0.35 3.3e-11 Primary biliary cholangitis; LIHC cis rs2071303 1.000 rs2071303 chr6:26091336 C/T cg18357526 chr6:26021779 HIST1H4A -0.44 -6.18 -0.32 1.79e-9 Intelligence (multi-trait analysis); LIHC cis rs2334880 0.602 rs12444212 chr16:71437689 T/C cg06353428 chr16:71660113 MARVELD3 -0.83 -7.85 -0.39 5.31e-14 Malaria; LIHC cis rs477692 0.905 rs7905466 chr10:131438937 A/T cg05714579 chr10:131428358 MGMT -0.46 -7.77 -0.39 9.44e-14 Response to temozolomide; LIHC cis rs4820539 0.802 rs5759587 chr22:23441515 C/G cg21100191 chr22:23484243 RTDR1 0.76 12.2 0.55 1.14e-28 Bone mineral density; LIHC cis rs11098499 0.662 rs13108589 chr4:120268102 G/C cg09307838 chr4:120376055 NA 0.71 11.35 0.52 1.47e-25 Corneal astigmatism; LIHC cis rs6456156 0.586 rs6456154 chr6:167472256 C/T cg12798992 chr6:167411361 FGFR1OP 0.44 6.8 0.34 4.81e-11 Primary biliary cholangitis; LIHC cis rs1403694 1.000 rs2304451 chr3:186437661 G/C cg12454167 chr3:186435060 KNG1 0.3 7.28 0.37 2.25e-12 Blood protein levels; LIHC cis rs6545883 0.929 rs6545873 chr2:61733012 T/C cg15711740 chr2:61764176 XPO1 -0.43 -6.1 -0.31 2.91e-9 Tuberculosis; LIHC cis rs801193 1.000 rs13239306 chr7:66136017 T/G cg00343986 chr7:65444356 GUSB -0.41 -6.06 -0.31 3.68e-9 Aortic root size; LIHC cis rs2243480 0.901 rs13237344 chr7:66022256 T/A cg05590025 chr7:65112418 INTS4L2 -0.53 -5.75 -0.3 2.01e-8 Diabetic kidney disease; LIHC cis rs6542838 0.702 rs6739176 chr2:99536846 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.22 -0.32 1.42e-9 Fear of minor pain; LIHC cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg07424592 chr7:64974309 NA 0.81 9.45 0.45 5.58e-19 Diabetic kidney disease; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg09367891 chr1:107599246 PRMT6 -0.72 -11.92 -0.54 1.24e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1670533 1.000 rs629260 chr4:1086764 A/G cg27284194 chr4:1044797 NA 0.61 8.99 0.44 1.72e-17 Recombination rate (females); LIHC cis rs1707322 0.963 rs11211238 chr1:46449415 G/A cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7903847 0.642 rs7092499 chr10:99140313 A/G cg08345082 chr10:99160200 RRP12 -0.36 -6.02 -0.31 4.51e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1982963 1.000 rs10139288 chr14:52506486 T/C cg10843707 chr14:52510701 NID2 -0.44 -7.7 -0.38 1.51e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.94 9.37 0.45 1.04e-18 Platelet count; LIHC cis rs4888262 0.604 rs12935075 chr16:74676033 A/T cg01733217 chr16:74700730 RFWD3 0.87 17.73 0.69 2.5e-50 Testicular germ cell tumor; LIHC cis rs2737618 0.722 rs1986405 chr1:200095935 C/G cg21825944 chr1:200113062 NR5A2 -0.46 -7.73 -0.39 1.24e-13 Uric acid levels; LIHC cis rs4076764 1.000 rs4469696 chr1:163424565 C/T cg24596788 chr1:163392923 NA -0.23 -7.15 -0.36 5.22e-12 Motion sickness; LIHC cis rs3924048 0.574 rs3923904 chr1:12616535 T/C cg00291366 chr1:12616550 NA 0.43 9.0 0.44 1.59e-17 Optic cup area; LIHC cis rs2404602 0.669 rs12148877 chr15:76919959 T/G cg03037974 chr15:76606532 NA 0.74 14.39 0.61 4.85e-37 Blood metabolite levels; LIHC cis rs3823572 0.542 rs62470443 chr7:133627499 G/A cg03336402 chr7:133662267 EXOC4 0.52 6.2 0.32 1.65e-9 Intelligence (multi-trait analysis); LIHC cis rs796364 1.000 rs796364 chr2:200716119 C/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.72 8.42 0.41 1.04e-15 Schizophrenia; LIHC cis rs1707322 0.785 rs10890348 chr1:46242423 G/T cg06784218 chr1:46089804 CCDC17 0.38 6.71 0.34 7.86e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2991971 1.000 rs518365 chr1:46010652 A/G cg24296786 chr1:45957014 TESK2 0.51 7.54 0.38 4.31e-13 High light scatter reticulocyte count; LIHC cis rs72634258 0.554 rs17374292 chr1:7881234 C/T cg26816564 chr1:7831052 VAMP3 0.63 6.03 0.31 4.24e-9 Inflammatory bowel disease; LIHC cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.56e-48 Diabetic kidney disease; LIHC cis rs10504229 0.679 rs72649107 chr8:58030453 C/A cg20607798 chr8:58055168 NA 0.46 6.71 0.34 7.96e-11 Developmental language disorder (linguistic errors); LIHC cis rs801193 0.660 rs2659897 chr7:66187715 A/G cg18252515 chr7:66147081 NA 0.42 6.05 0.31 3.83e-9 Aortic root size; LIHC cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg12310025 chr6:25882481 NA -0.64 -9.08 -0.44 8.7e-18 Blood metabolite levels; LIHC cis rs240764 0.782 rs239235 chr6:101100528 A/G cg09795085 chr6:101329169 ASCC3 0.53 7.46 0.37 7.07e-13 Neuroticism; LIHC cis rs6066825 0.555 rs717709 chr20:47305959 G/A cg18078177 chr20:47281410 PREX1 0.41 6.78 0.34 5.28e-11 Colorectal cancer; LIHC cis rs1577917 0.958 rs12660846 chr6:86573809 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC cis rs17685 0.697 rs28689051 chr7:75763624 G/A cg01364799 chr7:75623366 TMEM120A -0.48 -7.27 -0.37 2.4e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9309473 0.687 rs10165862 chr2:73610743 C/T cg20560298 chr2:73613845 ALMS1 -0.48 -7.89 -0.39 4.01e-14 Metabolite levels; LIHC cis rs826838 1.000 rs826886 chr12:39095797 A/G cg26384229 chr12:38710491 ALG10B 0.55 8.28 0.41 2.9e-15 Heart rate; LIHC cis rs6840360 0.967 rs7667197 chr4:152613952 G/A cg22705602 chr4:152727874 NA -0.32 -6.82 -0.35 4.2e-11 Intelligence (multi-trait analysis); LIHC cis rs9914988 0.887 rs11652710 chr17:27145075 C/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs12477438 0.520 rs13004491 chr2:99738008 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.68 0.78 3.75e-70 Chronic sinus infection; LIHC cis rs5758659 0.714 rs5758589 chr22:42518382 A/G cg19513890 chr22:42538836 CYP2D7P1 0.42 8.35 0.41 1.73e-15 Cognitive function; LIHC cis rs6545883 0.894 rs2167566 chr2:61519408 G/T cg14146966 chr2:61757674 XPO1 0.4 6.82 0.35 4.04e-11 Tuberculosis; LIHC cis rs477692 0.569 rs10764887 chr10:131321719 A/T cg19680672 chr10:131412579 MGMT -0.39 -6.02 -0.31 4.39e-9 Response to temozolomide; LIHC cis rs10883723 0.773 rs715439 chr10:104257809 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6545883 0.929 rs2593635 chr2:61634706 A/C cg15711740 chr2:61764176 XPO1 0.43 5.95 0.31 6.75e-9 Tuberculosis; LIHC trans rs11039798 0.565 rs7118675 chr11:48532063 C/A cg15704280 chr7:45808275 SEPT13 0.58 6.39 0.33 5.34e-10 Axial length; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21564803 chr22:43485544 TTLL1 0.43 6.44 0.33 4.02e-10 Cognitive function; LIHC cis rs9596863 0.784 rs4242932 chr13:54448513 A/C ch.13.53330881F chr13:54432880 NA -0.35 -5.89 -0.3 9.11e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1577917 0.655 rs2842600 chr6:86325632 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.24 -0.41 3.59e-15 Response to antipsychotic treatment; LIHC cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.84 -0.54 2.51e-27 Alzheimer's disease; LIHC cis rs6545883 0.965 rs2305155 chr2:61729258 A/G cg14146966 chr2:61757674 XPO1 0.48 8.57 0.42 3.61e-16 Tuberculosis; LIHC cis rs2153535 0.601 rs718504 chr6:8527512 A/G cg21535247 chr6:8435926 SLC35B3 0.65 8.63 0.42 2.43e-16 Motion sickness; LIHC cis rs1005277 0.579 rs1780130 chr10:38485378 T/A cg25427524 chr10:38739819 LOC399744 -0.72 -14.11 -0.61 5.78e-36 Extrinsic epigenetic age acceleration; LIHC cis rs10851411 0.697 rs17766258 chr15:42785137 A/G cg21293051 chr15:42870591 STARD9 -0.67 -5.91 -0.3 8.28e-9 Glucose homeostasis traits; LIHC cis rs1395 0.778 rs2580759 chr2:27432500 G/T cg23587288 chr2:27483067 SLC30A3 0.32 5.96 0.31 6.26e-9 Blood metabolite levels; LIHC cis rs240764 0.725 rs239212 chr6:101145178 G/A cg09795085 chr6:101329169 ASCC3 0.45 6.18 0.32 1.87e-9 Neuroticism; LIHC cis rs4638749 0.677 rs10185270 chr2:108838692 A/C cg06795125 chr2:108905320 SULT1C2 -0.3 -5.96 -0.31 6.23e-9 Blood pressure; LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg00809820 chr17:80708513 TBCD;FN3K 0.4 7.13 0.36 5.86e-12 Glycated hemoglobin levels; LIHC cis rs12980942 0.872 rs66724427 chr19:41776257 A/G cg25627403 chr19:41769009 HNRNPUL1 0.5 6.29 0.32 9.54e-10 Coronary artery disease; LIHC cis rs10463316 0.894 rs7707745 chr5:150765198 G/T cg03212797 chr5:150827313 SLC36A1 -0.42 -6.34 -0.32 7.12e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7412746 0.634 rs12562939 chr1:150951452 A/C cg17724175 chr1:150552817 MCL1 0.41 7.8 0.39 7.32e-14 Melanoma; LIHC cis rs67311347 0.869 rs7646899 chr3:40366982 A/G cg13409248 chr3:40428643 ENTPD3 0.42 6.76 0.34 6.05e-11 Renal cell carcinoma; LIHC cis rs7572733 0.534 rs6760891 chr2:198768166 T/G cg03934865 chr2:198174659 NA 0.47 6.85 0.35 3.51e-11 Dermatomyositis; LIHC cis rs10876993 0.784 rs1871417 chr12:58018979 C/T cg18357645 chr12:58087776 OS9 -0.49 -7.64 -0.38 2.15e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs11628318 0.614 rs4906254 chr14:103209153 C/T cg01864069 chr14:103024347 NA -0.34 -5.77 -0.3 1.81e-8 Platelet count; LIHC cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs28374715 0.578 rs10518717 chr15:41623368 C/G cg18705301 chr15:41695430 NDUFAF1 -1.27 -18.69 -0.71 3.23e-54 Ulcerative colitis; LIHC cis rs11577318 0.853 rs12728971 chr1:26626612 C/T cg00852783 chr1:26633632 UBXN11 0.42 6.8 0.35 4.66e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 12.16 0.55 1.57e-28 Colorectal cancer; LIHC cis rs6430585 0.583 rs2304371 chr2:136561557 A/G cg07169764 chr2:136633963 MCM6 1.08 16.2 0.66 3.28e-44 Corneal structure; LIHC cis rs12079745 0.793 rs12063056 chr1:169264107 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -7.12 -0.36 6.6e-12 QT interval; LIHC cis rs1671400 1.000 rs919586 chr8:13174671 A/G cg26799834 chr8:12899921 NA -0.53 -5.79 -0.3 1.61e-8 Obesity-related traits; LIHC trans rs877282 0.898 rs12359731 chr10:759497 A/G cg22713356 chr15:30763199 NA 1.37 12.28 0.55 5.73e-29 Uric acid levels; LIHC cis rs9611565 0.546 rs2092274 chr22:42123737 A/G cg03806693 chr22:41940476 POLR3H 0.83 9.31 0.45 1.54e-18 Vitiligo; LIHC cis rs8027181 0.959 rs11631352 chr15:73086473 A/G cg25996835 chr15:72978165 BBS4;HIGD2B -0.48 -7.31 -0.37 1.89e-12 Triglyceride levels; LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs8014204 0.604 rs12147862 chr14:75384471 C/T cg08847533 chr14:75593920 NEK9 -0.44 -7.11 -0.36 7.01e-12 Caffeine consumption; LIHC cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg03517284 chr6:25882590 NA -0.58 -7.1 -0.36 7.38e-12 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.791 rs6570694 chr6:145911204 C/G cg13319975 chr6:146136371 FBXO30 -0.4 -6.31 -0.32 8.87e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1865760 0.713 rs1130000 chr6:25985396 A/G cg18357526 chr6:26021779 HIST1H4A 0.41 6.09 0.31 3.01e-9 Height; LIHC cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg23205692 chr1:25664452 TMEM50A 0.38 6.05 0.31 3.9e-9 Plateletcrit;Mean corpuscular volume; LIHC cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC cis rs9322817 0.691 rs9377679 chr6:105345036 C/T cg02098413 chr6:105308735 HACE1 0.42 8.06 0.4 1.3e-14 Thyroid stimulating hormone; LIHC cis rs7762018 0.660 rs41265385 chr6:170068086 C/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.53 5.87 0.3 1.01e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs10870270 1.000 rs6560695 chr10:133774986 C/A cg08754478 chr10:133766260 PPP2R2D -0.55 -8.13 -0.4 8.04e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC trans rs1075232 0.655 rs78959602 chr15:31560784 A/G cg04373760 chr16:53404718 NA 0.67 6.43 0.33 4.22e-10 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs644799 0.965 rs10831430 chr11:95509638 T/C cg25478527 chr11:95522999 CEP57;FAM76B 0.41 5.73 0.3 2.23e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs748404 0.690 rs2924369 chr15:43777985 G/A cg02155558 chr15:43621948 ADAL;LCMT2 -0.47 -7.34 -0.37 1.61e-12 Lung cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25743719 chr2:10443138 HPCAL1 0.48 6.33 0.32 7.59e-10 Lung function (FEV1/FVC); LIHC cis rs17001868 0.568 rs9611311 chr22:40733951 T/C cg07138101 chr22:40742427 ADSL 0.55 6.51 0.33 2.6200000000000003e-10 Mammographic density (dense area); LIHC cis rs6540556 0.723 rs12060420 chr1:209906819 T/G cg05527609 chr1:210001259 C1orf107 -0.58 -7.83 -0.39 6.21e-14 Red blood cell count; LIHC cis rs2576037 0.542 rs4630643 chr18:44508142 G/A cg19077165 chr18:44547161 KATNAL2 -0.47 -6.88 -0.35 2.87e-11 Personality dimensions; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11153505 chr13:113378377 ATP11A -0.4 -6.17 -0.32 1.92e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3806843 0.735 rs809635 chr5:140081791 A/G cg26395211 chr5:140044315 WDR55 0.4 5.87 0.3 1.01e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1552244 0.882 rs17081288 chr3:10042113 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.17 -0.44 4.37e-18 Alzheimer's disease; LIHC cis rs7520050 1.000 rs12410070 chr1:46358882 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.78 0.3 1.69e-8 Red blood cell count;Reticulocyte count; LIHC cis rs12477438 0.798 rs4850894 chr2:99629396 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.41 -0.53 8.75e-26 Chronic sinus infection; LIHC cis rs3845702 0.733 rs12693217 chr2:180841914 T/G cg01881094 chr2:180872142 CWC22 -1.13 -9.96 -0.47 1.12e-20 Schizophrenia; LIHC cis rs1003719 0.715 rs2835659 chr21:38567902 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.24 -0.48 1.21e-21 Eye color traits; LIHC cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg03264133 chr6:25882463 NA 0.49 6.17 0.32 1.92e-9 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg23131131 chr22:24373011 LOC391322 -0.68 -9.84 -0.47 2.78e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11229555 0.645 rs72917641 chr11:58227320 A/C cg15696309 chr11:58395628 NA -0.64 -7.36 -0.37 1.38e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1267303 0.642 rs1267301 chr1:46992853 C/G cg25110126 chr1:46999211 NA -0.53 -6.55 -0.33 2.05e-10 Monobrow; LIHC cis rs6570726 0.935 rs371744 chr6:145841024 C/T cg23711669 chr6:146136114 FBXO30 0.56 10.32 0.49 6.24e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs4407350 0.609 rs1962220 chr22:44888063 G/A cg11695653 chr22:44894386 LDOC1L 0.36 6.03 0.31 4.34e-9 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg13395646 chr4:1353034 KIAA1530 -0.61 -9.06 -0.44 1.06e-17 Obesity-related traits; LIHC cis rs12477438 0.501 rs9941561 chr2:99753829 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.38 0.59 3.85e-33 Chronic sinus infection; LIHC cis rs3892630 0.878 rs1559177 chr19:33210646 A/G cg22980127 chr19:33182716 NUDT19 0.98 11.65 0.53 1.24e-26 Red blood cell traits; LIHC cis rs11724804 0.532 rs62297079 chr4:879977 G/A cg23939001 chr4:940644 TMEM175 0.48 7.37 0.37 1.27e-12 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs6977660 1.000 rs6959889 chr7:19822024 A/C cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs7309 0.935 rs11884495 chr2:162059969 A/T cg16506815 chr2:162101123 NA 0.57 9.86 0.47 2.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs7662987 0.517 rs2924580 chr4:100032168 C/G cg13256891 chr4:100009986 ADH5 0.61 6.3 0.32 9.42e-10 Smoking initiation; LIHC cis rs1983891 0.955 rs6917029 chr6:41548540 C/G cg20194872 chr6:41519635 FOXP4 0.4 6.48 0.33 3.25e-10 Prostate cancer; LIHC cis rs3806843 0.676 rs2563304 chr5:140072057 C/T cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg10802521 chr3:52805072 NEK4 -0.37 -5.74 -0.3 2.12e-8 Bipolar disorder; LIHC cis rs752092 0.925 rs8032007 chr15:101790817 C/T cg25114630 chr15:101792522 CHSY1 -0.6 -7.78 -0.39 8.49e-14 Corneal structure; LIHC cis rs11062517 1 rs11062517 chr12:3235839 C/T cg07248242 chr12:3281520 TSPAN9 -0.29 -5.79 -0.3 1.63e-8 Platelet distribution width; LIHC cis rs7503168 0.908 rs9907772 chr17:34000628 G/A cg20932281 chr17:33905541 PEX12 0.54 7.08 0.36 8.39e-12 Plateletcrit; LIHC cis rs4242434 0.672 rs10099266 chr8:22484268 C/G cg03733263 chr8:22462867 KIAA1967 0.75 12.5 0.56 8.42e-30 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC trans rs8113308 0.810 rs8104323 chr19:52443245 C/T cg14959425 chr7:20447707 ITGB8 -0.48 -6.15 -0.32 2.22e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs4409675 0.527 rs1884469 chr1:28239434 G/A cg23691781 chr1:28212827 C1orf38 0.32 7.44 0.37 8.48e-13 Corneal astigmatism; LIHC cis rs1577917 0.740 rs7771612 chr6:86264374 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.3 0.32 9.42e-10 Response to antipsychotic treatment; LIHC cis rs12701220 0.655 rs10241018 chr7:1144774 G/C cg18765753 chr7:1198926 ZFAND2A -0.42 -5.83 -0.3 1.28e-8 Bronchopulmonary dysplasia; LIHC cis rs9303401 0.659 rs11079357 chr17:56902778 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.2 0.55 1.11e-28 Cognitive test performance; LIHC cis rs62064224 0.902 rs17732573 chr17:30627664 C/T cg25809561 chr17:30822961 MYO1D -0.59 -8.54 -0.42 4.39e-16 Schizophrenia; LIHC cis rs56235845 0.694 rs9313758 chr5:176773091 T/G cg06060754 chr5:176797920 RGS14 0.47 6.7 0.34 8.53e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs12701220 0.857 rs1057558 chr7:1062366 A/G cg26769984 chr7:1090371 C7orf50 0.58 7.36 0.37 1.36e-12 Bronchopulmonary dysplasia; LIHC cis rs1865760 0.566 rs9358904 chr6:26068566 C/T cg17691542 chr6:26056736 HIST1H1C 0.41 5.97 0.31 5.97e-9 Height; LIHC cis rs637571 0.522 rs550435 chr11:65732651 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.86 0.3 1.1e-8 Eosinophil percentage of white cells; LIHC cis rs2274273 0.870 rs13379169 chr14:55741287 C/T cg04306507 chr14:55594613 LGALS3 0.32 5.97 0.31 5.81e-9 Protein biomarker; LIHC cis rs6138458 1.000 rs227651 chr20:24929834 A/G cg26195577 chr20:24973756 C20orf3 1.17 15.21 0.64 2.92e-40 Blood protein levels; LIHC cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.23e-9 Menopause (age at onset); LIHC cis rs1552244 0.765 rs17050675 chr3:10027686 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.57 -0.5 8.95e-23 Alzheimer's disease; LIHC cis rs7072216 0.587 rs3814141 chr10:100171028 G/A cg26618903 chr10:100175079 PYROXD2 -0.37 -5.75 -0.3 2.03e-8 Metabolite levels; LIHC cis rs12594515 1.000 rs6493169 chr15:45986994 A/G cg01629716 chr15:45996671 NA -0.51 -9.37 -0.45 1.04e-18 Waist circumference;Weight; LIHC cis rs11098499 0.955 rs11944880 chr4:120159334 A/G cg09307838 chr4:120376055 NA -0.74 -10.96 -0.51 3.8e-24 Corneal astigmatism; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs11888559 0.511 rs6736046 chr2:204006242 G/A cg24605529 chr2:203879461 NBEAL1 0.8 6.1 0.31 2.8e-9 Height; LIHC cis rs35306767 0.855 rs61830931 chr10:932497 T/C cg20503657 chr10:835505 NA 1.32 14.12 0.61 5.57e-36 Eosinophil percentage of granulocytes; LIHC cis rs12478296 1.000 rs59036157 chr2:243040228 C/A cg18898632 chr2:242989856 NA -0.69 -8.75 -0.43 1.01e-16 Obesity-related traits; LIHC cis rs9790314 0.521 rs1450523 chr3:161077270 G/A cg03342759 chr3:160939853 NMD3 -0.43 -6.24 -0.32 1.26e-9 Morning vs. evening chronotype; LIHC cis rs929354 0.709 rs1182363 chr7:157019151 A/G cg05182265 chr7:156933206 UBE3C 0.33 6.3 0.32 8.96e-10 Body mass index; LIHC cis rs7131987 0.868 rs7958210 chr12:29395181 G/C cg12903224 chr12:29470962 FAR2 -0.38 -6.04 -0.31 4.07e-9 QT interval; LIHC cis rs7666738 0.785 rs11944120 chr4:99079932 A/C cg05340658 chr4:99064831 C4orf37 0.71 10.75 0.5 2.03e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs1163251 0.837 rs660073 chr1:120245173 T/C cg19096424 chr1:120255104 PHGDH 0.63 8.1 0.4 9.82e-15 Blood metabolite levels; LIHC cis rs6867032 1.000 rs2129471 chr5:2016236 C/G cg26168224 chr5:2018326 NA 0.31 7.57 0.38 3.48e-13 Gut microbiome composition (winter); LIHC cis rs4555082 0.957 rs2816629 chr14:105737261 G/A cg10792982 chr14:105748885 BRF1 0.44 6.17 0.32 1.94e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs5769765 0.542 rs761878 chr22:50249677 A/G cg09182678 chr22:50328711 NA 0.49 6.06 0.31 3.69e-9 Schizophrenia; LIHC cis rs2075371 1.000 rs1862051 chr7:133981021 G/A cg20476274 chr7:133979776 SLC35B4 0.75 12.57 0.56 4.94e-30 Mean platelet volume; LIHC trans rs7246657 0.943 rs6508732 chr19:38000468 C/T cg10208301 chr11:6592745 DNHD1 0.45 6.37 0.33 6.09e-10 Coronary artery calcification; LIHC cis rs875971 0.545 rs4718335 chr7:65804606 C/T cg11764359 chr7:65958608 NA 0.58 8.16 0.4 6.57e-15 Aortic root size; LIHC cis rs4268898 0.662 rs2303291 chr2:24431184 C/T cg06627628 chr2:24431161 ITSN2 -0.77 -9.73 -0.47 6.65e-20 Asthma; LIHC cis rs1144333 0.655 rs12405994 chr1:76435420 A/T cg03433033 chr1:76189801 ACADM 0.54 7.64 0.38 2.18e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg05552183 chr6:42928497 GNMT 0.68 10.25 0.48 1.15e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg08677398 chr8:58056175 NA 0.4 6.04 0.31 3.94e-9 Developmental language disorder (linguistic errors); LIHC cis rs9527 0.641 rs4919684 chr10:104587024 A/G cg15744005 chr10:104629667 AS3MT -0.34 -6.24 -0.32 1.28e-9 Arsenic metabolism; LIHC cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg15691649 chr6:25882328 NA -0.53 -6.96 -0.35 1.79e-11 Intelligence (multi-trait analysis); LIHC cis rs4820294 0.669 rs732857 chr22:38060850 C/T cg00292662 chr22:38071168 LGALS1 0.4 6.74 0.34 6.93e-11 Fat distribution (HIV); LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg21548813 chr6:291882 DUSP22 -0.54 -7.42 -0.37 9.08e-13 Menopause (age at onset); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01485483 chr17:10600905 C17orf48;SCO1 -0.51 -6.14 -0.32 2.34e-9 Systolic blood pressure; LIHC cis rs919433 0.680 rs788021 chr2:198293691 T/C cg03934865 chr2:198174659 NA 0.55 8.35 0.41 1.71e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg03806693 chr22:41940476 POLR3H -1.12 -13.42 -0.59 2.76e-33 Vitiligo; LIHC cis rs2268241 0.938 rs9974603 chr21:34776300 C/A cg14850771 chr21:34775459 IFNGR2 0.9 14.07 0.61 8.42e-36 Obesity-related traits; LIHC cis rs6500602 0.702 rs4786511 chr16:4571645 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 7.81 0.39 6.87e-14 Schizophrenia; LIHC cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.26 -0.55 6.75e-29 Alzheimer's disease; LIHC cis rs9814567 0.722 rs13083717 chr3:134348796 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.51 6.4 0.33 5.14e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24712243 chr11:61310195 SYT7 0.46 6.68 0.34 9.45e-11 Longevity; LIHC cis rs9811920 0.638 rs2452321 chr3:99638836 T/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.81 0.3 1.43e-8 Axial length; LIHC cis rs992157 0.798 rs2382819 chr2:219155909 G/T cg20019365 chr2:219134978 PNKD;AAMP -0.77 -11.96 -0.54 8.84e-28 Colorectal cancer; LIHC cis rs11920354 0.642 rs9812878 chr3:47182787 T/C cg16586182 chr3:47516702 SCAP -0.47 -8.18 -0.4 5.66e-15 Granulocyte count;Sum neutrophil eosinophil counts; LIHC cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.73 7.16 0.36 4.86e-12 Lung function (FEV1/FVC); LIHC cis rs7903847 0.642 rs11189206 chr10:99167802 T/C cg06359132 chr10:99160096 RRP12 -0.38 -5.96 -0.31 6.4e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs9916302 0.861 rs11658219 chr17:37709782 G/A cg00129232 chr17:37814104 STARD3 -0.4 -6.25 -0.32 1.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg03517284 chr6:25882590 NA -0.46 -6.93 -0.35 2.08e-11 Height; LIHC cis rs7772486 0.875 rs7739418 chr6:146359188 G/A cg13319975 chr6:146136371 FBXO30 -0.34 -5.74 -0.3 2.08e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg05552183 chr6:42928497 GNMT 0.78 11.89 0.54 1.65e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2839627 0.561 rs9808758 chr21:44262390 G/C cg03543861 chr21:44258195 NA 0.48 7.39 0.37 1.15e-12 Information processing speed; LIHC cis rs7903847 0.642 rs11189200 chr10:99156273 C/G cg06359132 chr10:99160096 RRP12 -0.42 -6.47 -0.33 3.42e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs1570884 0.516 rs9316463 chr13:50176844 G/A cg03651054 chr13:50194643 NA 0.37 6.51 0.33 2.7e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg08392591 chr16:89556376 ANKRD11 0.55 8.88 0.43 3.88e-17 Multiple myeloma (IgH translocation); LIHC cis rs28647808 0.881 rs7029386 chr9:136263736 T/C cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs12971120 0.588 rs12606654 chr18:72126710 C/T cg26446133 chr18:72167187 CNDP2 -0.49 -6.36 -0.33 6.34e-10 Refractive error; LIHC cis rs473651 0.716 rs548179 chr2:239320505 G/A cg18131467 chr2:239335373 ASB1 1.04 19.42 0.72 3.65e-57 Multiple system atrophy; LIHC trans rs1814175 0.586 rs2866862 chr11:49954588 T/C cg03929089 chr4:120376271 NA -0.84 -15.88 -0.65 6.5e-43 Height; LIHC cis rs11112613 0.775 rs10778413 chr12:105962118 G/A cg03607813 chr12:105948248 NA 0.62 11.84 0.54 2.52e-27 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs941408 0.515 rs4624312 chr19:2774460 T/C cg19676328 chr12:49525230 TUBA1B -0.43 -6.06 -0.31 3.59e-9 Total cholesterol levels; LIHC cis rs4853012 0.887 rs6737314 chr2:74339586 A/G cg01017244 chr2:74357527 NA 0.63 11.06 0.51 1.58e-24 Gestational age at birth (maternal effect); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03041860 chr2:208489911 FAM119A 0.41 6.9 0.35 2.55e-11 Cognitive function; LIHC cis rs1144333 1.000 rs1144333 chr1:76275100 A/G cg22875332 chr1:76189707 ACADM -0.42 -6.78 -0.34 5.34e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs12908161 1.000 rs12910012 chr15:85298662 T/C cg17507749 chr15:85114479 UBE2QP1 0.62 7.09 0.36 7.9e-12 Schizophrenia; LIHC cis rs1165668 0.727 rs2722176 chr12:104313943 T/C cg21863207 chr12:104234989 NT5DC3 0.46 8.01 0.4 1.77e-14 Coronary heart disease (SNP X SNP interaction); LIHC cis rs2576037 0.796 rs2571030 chr18:44573854 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.5 -7.67 -0.38 1.81e-13 Personality dimensions; LIHC cis rs3806843 0.766 rs2251860 chr5:140048209 T/C cg19875535 chr5:140030758 IK -0.39 -6.31 -0.32 8.75e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs11577318 0.812 rs3795683 chr1:26632831 C/A cg10402321 chr1:26617780 UBXN11 -0.38 -5.86 -0.3 1.11e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs4819052 0.851 rs7275874 chr21:46671223 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.33 0.52 1.82e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs882732 1.000 rs17091071 chr14:95033708 A/C cg14866387 chr14:95027382 SERPINA4 -0.45 -6.73 -0.34 7.03e-11 Blood protein levels; LIHC cis rs7918232 0.830 rs7087033 chr10:27392522 A/G cg14240646 chr10:27532245 ACBD5 -0.67 -6.39 -0.33 5.37e-10 Breast cancer; LIHC cis rs769267 0.965 rs2315281 chr19:19480099 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.53 -8.13 -0.4 8.08e-15 Tonsillectomy; LIHC cis rs4803468 0.934 rs11880674 chr19:41889423 A/T cg09537434 chr19:41945824 ATP5SL -0.99 -20.12 -0.74 5.95e-60 Height; LIHC cis rs7843479 0.601 rs3824338 chr8:21864540 A/C cg17168535 chr8:21777572 XPO7 0.51 9.37 0.45 9.75e-19 Mean corpuscular volume; LIHC cis rs798554 0.721 rs2527680 chr7:2892361 C/T cg19346786 chr7:2764209 NA -0.37 -6.08 -0.31 3.25e-9 Height; LIHC cis rs10791097 0.748 rs2282579 chr11:130735482 C/T cg12179176 chr11:130786555 SNX19 0.8 13.07 0.58 5.92e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs644799 0.662 rs35793328 chr11:95490896 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.62 8.09 0.4 1.03e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3762637 1.000 rs7642869 chr3:122190786 T/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs9457247 0.967 rs2769355 chr6:167380493 G/A cg23791538 chr6:167370224 RNASET2 0.69 11.76 0.54 4.7e-27 Crohn's disease; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg07133347 chr1:107600762 PRMT6 -0.44 -6.66 -0.34 1.1e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg10360323 chr17:41437877 NA 0.4 6.0 0.31 5.04e-9 Menopause (age at onset); LIHC cis rs2012796 0.913 rs8010181 chr14:81820125 T/C cg02996355 chr14:81879375 NA 0.43 6.43 0.33 4.2e-10 Night sleep phenotypes; LIHC cis rs17401966 0.800 rs2039778 chr1:10354601 A/G cg19773385 chr1:10388646 KIF1B -0.41 -7.45 -0.37 7.47e-13 Hepatocellular carcinoma; LIHC cis rs2408955 0.541 rs11168428 chr12:48547128 A/G cg21466736 chr12:48725269 NA 0.63 8.92 0.43 2.96e-17 Glycated hemoglobin levels; LIHC cis rs3099143 1.000 rs3110378 chr15:77127983 G/A cg21673338 chr15:77095150 SCAPER -0.5 -7.65 -0.38 2.03e-13 Recalcitrant atopic dermatitis; LIHC cis rs918629 0.528 rs2547997 chr5:95254171 G/T cg10483112 chr5:95245456 ELL2 -0.38 -7.14 -0.36 5.48e-12 IgG glycosylation; LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg00091569 chr3:40428383 ENTPD3 0.38 6.38 0.33 5.64e-10 Renal cell carcinoma; LIHC cis rs861318 0.702 rs74122232 chr1:159006423 G/A cg11003133 chr1:159046391 AIM2 -0.35 -6.7 -0.34 8.71e-11 Obesity-related traits; LIHC cis rs12477438 0.520 rs4851188 chr2:99745898 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.13 0.61 5.14e-36 Chronic sinus infection; LIHC cis rs12477438 0.520 rs2632276 chr2:99779655 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.82 14.15 0.61 4.03e-36 Chronic sinus infection; LIHC cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.35 0.37 1.43e-12 Obesity-related traits; LIHC cis rs4555082 0.830 rs2816648 chr14:105708289 C/T cg06808227 chr14:105710500 BRF1 -0.55 -7.21 -0.36 3.6e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs965469 0.901 rs6139080 chr20:3314506 A/G cg25506879 chr20:3388711 C20orf194 -0.56 -6.81 -0.35 4.32e-11 IFN-related cytopenia; LIHC cis rs10876993 0.680 rs2277322 chr12:58009202 T/C cg18357645 chr12:58087776 OS9 -0.49 -7.66 -0.38 1.96e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.31e-9 Developmental language disorder (linguistic errors); LIHC cis rs10106298 0.846 rs2436936 chr8:103677723 C/A cg10187029 chr8:103597600 NA 0.47 6.36 0.33 6.56e-10 Schizophrenia; LIHC cis rs929354 0.772 rs10229630 chr7:157004790 C/T cg17757837 chr7:157058334 UBE3C 0.74 12.03 0.55 4.76e-28 Body mass index; LIHC cis rs2075165 0.901 rs1804999 chr1:156219450 A/G cg20302342 chr1:156215951 PAQR6 0.32 6.05 0.31 3.72e-9 Tonsillectomy; LIHC cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg21782813 chr7:2030301 MAD1L1 0.46 7.75 0.39 1.07e-13 Bipolar disorder and schizophrenia; LIHC cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg07424592 chr7:64974309 NA 0.8 9.21 0.45 3.38e-18 Diabetic kidney disease; LIHC cis rs992157 0.796 rs55680399 chr2:219160621 T/C cg20019365 chr2:219134978 PNKD;AAMP 0.8 12.91 0.57 2.53e-31 Colorectal cancer; LIHC cis rs9527 0.662 rs10786714 chr10:104598606 G/C cg15744005 chr10:104629667 AS3MT -0.36 -6.57 -0.33 1.86e-10 Arsenic metabolism; LIHC cis rs2806561 0.765 rs1612905 chr1:23510023 G/T cg12483005 chr1:23474871 LUZP1 0.46 7.33 0.37 1.66e-12 Height; LIHC cis rs2066819 0.892 rs17118431 chr12:56667100 A/G cg26714650 chr12:56694279 CS -1.4 -13.76 -0.6 1.3600000000000001e-34 Psoriasis vulgaris; LIHC trans rs9388451 0.626 rs1268074 chr6:126107791 G/C cg05039488 chr6:79577232 IRAK1BP1 -0.62 -10.38 -0.49 4.15e-22 Brugada syndrome; LIHC trans rs61931739 0.500 rs11053271 chr12:34545407 C/A cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs3812831 0.599 rs428636 chr13:114927133 T/C cg08824895 chr13:115047677 UPF3A 0.5 7.05 0.36 9.95e-12 Schizophrenia; LIHC trans rs2739330 0.752 rs2330634 chr22:24250795 C/G cg06437703 chr8:37914619 EIF4EBP1 -0.5 -7.35 -0.37 1.49e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11628318 0.570 rs4906231 chr14:103062227 T/C cg01864069 chr14:103024347 NA -0.46 -7.39 -0.37 1.12e-12 Platelet count; LIHC trans rs17685 0.753 rs1637045 chr7:75703895 T/C cg19862616 chr7:65841803 NCRNA00174 0.92 18.67 0.71 3.82e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12744310 0.887 rs35464028 chr1:41800474 T/G cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1559088 0.847 rs8100392 chr19:33605933 T/C cg27124370 chr19:33622961 WDR88 0.52 8.19 0.41 5.16e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg02990361 chr1:107599529 PRMT6 0.65 11.02 0.51 2.28e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1055129 0.560 rs56248937 chr17:73915153 T/A cg19302996 chr17:73780495 UNK -0.46 -6.67 -0.34 1.05e-10 White matter hyperintensity burden; LIHC cis rs4919694 1.000 rs76892505 chr10:104719290 G/A cg04362960 chr10:104952993 NT5C2 1.09 7.82 0.39 6.53e-14 Arsenic metabolism; LIHC cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs769267 0.930 rs4808955 chr19:19552413 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.11 0.31 2.72e-9 Tonsillectomy; LIHC cis rs7937682 0.889 rs567859 chr11:111486738 A/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg11062466 chr8:58055876 NA 0.52 7.54 0.38 4.33e-13 Developmental language disorder (linguistic errors); LIHC cis rs2637266 0.783 rs846645 chr10:78516000 A/G cg18941641 chr10:78392320 NA 0.27 5.84 0.3 1.22e-8 Pulmonary function; LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs35883536 0.935 rs3904674 chr1:101138932 C/T cg14515779 chr1:101123966 NA -0.69 -13.78 -0.6 1.15e-34 Monocyte count; LIHC cis rs769267 0.965 rs2905425 chr19:19475717 G/C cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.14 -0.31 2.32e-9 Tonsillectomy; LIHC cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg02931644 chr1:25747376 RHCE 0.33 7.08 0.36 8.47e-12 Erythrocyte sedimentation rate; LIHC cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg03264133 chr6:25882463 NA 0.93 12.68 0.57 1.9e-30 Blood metabolite levels; LIHC cis rs9583531 0.891 rs61969072 chr13:111380701 T/G cg24331049 chr13:111365604 ING1 -0.67 -8.93 -0.43 2.75e-17 Coronary artery disease; LIHC cis rs7587476 0.906 rs62201985 chr2:215658638 A/G cg04004882 chr2:215674386 BARD1 0.53 6.45 0.33 3.83e-10 Neuroblastoma; LIHC cis rs6952808 0.929 rs11761270 chr7:1923695 C/T cg14004847 chr7:1930337 MAD1L1 -0.5 -7.22 -0.36 3.33e-12 Bipolar disorder and schizophrenia; LIHC cis rs6754311 0.731 rs745500 chr2:136583192 G/A cg25344623 chr2:136566232 LCT 0.41 8.48 0.42 7.09e-16 Mosquito bite size; LIHC cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg18357526 chr6:26021779 HIST1H4A 0.41 6.26 0.32 1.15e-9 Height; LIHC cis rs4665809 1.000 rs6546727 chr2:26275282 C/T cg04944784 chr2:26401820 FAM59B -0.65 -8.29 -0.41 2.7e-15 Gut microbiome composition (summer); LIHC cis rs4474465 0.679 rs4945288 chr11:78244823 C/A cg27205649 chr11:78285834 NARS2 0.4 6.12 0.31 2.61e-9 Alzheimer's disease (survival time); LIHC trans rs783540 0.846 rs783539 chr15:83254070 A/C cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.06 -0.31 3.51e-9 Schizophrenia; LIHC cis rs2836974 0.644 rs1882779 chr21:40690938 T/C cg17971929 chr21:40555470 PSMG1 -0.44 -6.49 -0.33 3.08e-10 Cognitive function; LIHC cis rs526821 0.595 rs517627 chr11:55356489 C/T cg04317927 chr11:55418816 OR4S2 0.47 8.98 0.44 1.86e-17 Pediatric bone mineral density (spine); LIHC cis rs546131 0.928 rs552627 chr11:34826680 G/A cg06937548 chr11:34938143 PDHX;APIP 0.54 7.31 0.37 1.95e-12 Lung disease severity in cystic fibrosis; LIHC cis rs9733 0.596 rs6681990 chr1:150695929 A/G cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs17666538 0.535 rs4338080 chr8:615598 A/G cg07234876 chr8:600039 NA 0.89 7.01 0.35 1.24e-11 IgG glycosylation; LIHC cis rs2629540 0.847 rs10901811 chr10:126417914 G/A cg08799069 chr10:126477246 METTL10 0.45 7.13 0.36 5.92e-12 Cocaine dependence; LIHC cis rs739401 0.566 rs7931504 chr11:3026712 C/T cg20651018 chr11:3035856 CARS -0.35 -5.94 -0.31 7.09e-9 Longevity; LIHC cis rs7072216 0.655 rs3830024 chr10:100176106 G/A cg26618903 chr10:100175079 PYROXD2 -0.4 -6.06 -0.31 3.56e-9 Metabolite levels; LIHC cis rs12497850 1.000 rs4858831 chr3:48735558 C/T cg06212747 chr3:49208901 KLHDC8B 0.49 6.46 0.33 3.64e-10 Parkinson's disease; LIHC cis rs34330 0.562 rs10845615 chr12:12863470 C/T cg04607235 chr12:12878440 APOLD1 -0.76 -9.49 -0.46 4.06e-19 Systemic lupus erythematosus; LIHC cis rs875971 0.545 rs11770063 chr7:65783016 G/A cg11764359 chr7:65958608 NA 0.58 8.16 0.4 6.57e-15 Aortic root size; LIHC cis rs1789 0.903 rs4616746 chr4:15673098 A/G cg24225360 chr4:15471699 CC2D2A -0.38 -5.91 -0.3 8.24e-9 Blood protein levels; LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.93 0.57 2.1e-31 Prudent dietary pattern; LIHC cis rs74233809 1.000 rs11191593 chr10:104939215 T/C cg03493300 chr10:104813866 CNNM2 0.46 6.14 0.32 2.29e-9 Birth weight; LIHC cis rs1003719 0.680 rs2835630 chr21:38521842 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -11.12 -0.52 1.01e-24 Eye color traits; LIHC cis rs6912958 0.667 rs7746545 chr6:88090225 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.39 7.54 0.38 4.13e-13 Monocyte percentage of white cells; LIHC cis rs4555082 0.830 rs2816648 chr14:105708289 C/T cg10792982 chr14:105748885 BRF1 0.44 5.9 0.3 8.79e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs317689 0.513 rs317659 chr12:69686132 T/A cg22834771 chr12:69754056 YEATS4 -0.4 -6.47 -0.33 3.44e-10 Response to diuretic therapy; LIHC cis rs7953249 0.618 rs7954331 chr12:121398657 G/T cg02403541 chr12:121454288 C12orf43 -0.42 -7.39 -0.37 1.12e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs10792665 0.575 rs10792653 chr11:82560312 T/G cg24227371 chr11:82718527 RAB30 -0.26 -6.27 -0.32 1.1e-9 Obesity-related traits; LIHC trans rs2270927 0.510 rs2913265 chr5:75603886 C/A cg13563193 chr19:33072644 PDCD5 0.93 8.96 0.44 2.09e-17 Mean corpuscular volume; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg03390569 chr2:54013802 LOC100302652;ASB3;ERLEC1 -0.44 -6.65 -0.34 1.15e-10 Body mass index; LIHC cis rs3806843 0.735 rs6849 chr5:140086191 G/T cg19875535 chr5:140030758 IK -0.41 -6.77 -0.34 5.46e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs61712019 0.679 rs1950161 chr2:77719972 C/T cg11252801 chr2:77748917 LRRTM4 0.56 7.73 0.39 1.2e-13 Schizophrenia; LIHC trans rs7618501 0.633 rs6771546 chr3:49968572 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.55 8.98 0.44 1.87e-17 Intelligence (multi-trait analysis); LIHC cis rs875971 0.792 rs6971752 chr7:65737986 G/A cg11764359 chr7:65958608 NA -0.85 -15.03 -0.63 1.49e-39 Aortic root size; LIHC cis rs7508 0.511 rs371922 chr8:17900003 T/C cg01800426 chr8:17659068 MTUS1 -0.44 -6.93 -0.35 2.12e-11 Atrial fibrillation; LIHC cis rs10078 0.515 rs2672739 chr5:443447 A/C cg07599136 chr5:415885 AHRR 0.8 12.92 0.57 2.29e-31 Fat distribution (HIV); LIHC cis rs7552404 0.731 rs931507 chr1:76401577 G/A cg03433033 chr1:76189801 ACADM -0.55 -6.77 -0.34 5.58e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7100689 0.646 rs1340382 chr10:82096997 G/C cg01528321 chr10:82214614 TSPAN14 0.77 10.38 0.49 3.89e-22 Post bronchodilator FEV1; LIHC cis rs1008375 0.966 rs12509962 chr4:17680292 G/A cg16339924 chr4:17578868 LAP3 0.4 5.89 0.3 9.38e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.81 7.89 0.39 4.01e-14 Platelet count; LIHC cis rs477692 0.569 rs1762418 chr10:131303353 G/A cg05714579 chr10:131428358 MGMT 0.42 6.58 0.34 1.82e-10 Response to temozolomide; LIHC cis rs2933343 0.700 rs883602 chr3:128653952 A/G cg25356066 chr3:128598488 ACAD9 0.52 7.34 0.37 1.62e-12 IgG glycosylation; LIHC cis rs9311474 0.632 rs6445528 chr3:52572447 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.54 -9.51 -0.46 3.5e-19 Electroencephalogram traits; LIHC cis rs7762018 0.607 rs7759404 chr6:170135728 A/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.56 6.82 0.35 4.02e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs67460515 0.892 rs35310734 chr3:160943209 T/G cg17135325 chr3:160939158 NMD3 0.53 7.52 0.38 4.72e-13 Parkinson's disease; LIHC cis rs611744 0.967 rs677330 chr8:109177572 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs249954 0.512 rs703769 chr16:23654509 T/G cg01460202 chr16:23706506 ERN2 0.35 5.71 0.3 2.42e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs4253772 0.591 rs6519994 chr22:46656805 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.7 -6.3 -0.32 9.29e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs4407350 1.000 rs5765723 chr22:44921554 C/T cg11695653 chr22:44894386 LDOC1L -0.36 -6.06 -0.31 3.55e-9 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05673432 chr3:15919505 NA 0.53 6.7 0.34 8.83e-11 Hepatitis; LIHC cis rs919433 0.680 rs788022 chr2:198280586 T/C cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.84e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs61776719 0.738 rs7555461 chr1:38444749 T/C cg18451016 chr1:38461880 NA -0.37 -5.83 -0.3 1.31e-8 Coronary artery disease; LIHC cis rs225245 0.782 rs178649 chr17:33908197 C/G cg05299278 chr17:33885742 SLFN14 0.21 5.75 0.3 1.95e-8 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs17854409 1.000 rs66634465 chr20:61482306 C/T cg06598544 chr20:61472147 COL9A3 -0.83 -7.9 -0.39 3.97e-14 Obesity-related traits; LIHC cis rs9733 0.596 rs3087960 chr1:150620569 C/G cg17724175 chr1:150552817 MCL1 0.48 9.74 0.47 6.14e-20 Tonsillectomy; LIHC cis rs13108904 0.901 rs12641735 chr4:1304434 G/C cg20887711 chr4:1340912 KIAA1530 0.59 9.24 0.45 2.74e-18 Obesity-related traits; LIHC cis rs2637266 0.626 rs2583067 chr10:78555804 A/G cg18941641 chr10:78392320 NA 0.3 6.46 0.33 3.58e-10 Pulmonary function; LIHC trans rs1005277 0.579 rs1780136 chr10:38501453 A/G cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs35306767 0.715 rs1871622 chr10:1049309 T/G cg20503657 chr10:835505 NA 0.83 7.99 0.4 2.07e-14 Eosinophil percentage of granulocytes; LIHC cis rs6594499 0.872 rs7702774 chr5:110460851 G/T cg04022379 chr5:110408740 TSLP 0.49 8.07 0.4 1.18e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1400745 0.729 rs1741196 chr14:35347020 G/A cg16230307 chr14:35515116 FAM177A1 0.38 6.1 0.31 2.9e-9 Monocyte count; LIHC cis rs4845459 0.967 rs6700160 chr1:152593024 A/C cg20634798 chr1:152595351 LCE3A -0.31 -6.03 -0.31 4.26e-9 Psoriasis; LIHC cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg23758822 chr17:41437982 NA 0.93 17.85 0.69 8.09e-51 Menopause (age at onset); LIHC cis rs1670533 1.000 rs34956924 chr4:1047270 T/C cg27284194 chr4:1044797 NA 0.54 7.6 0.38 2.78e-13 Recombination rate (females); LIHC cis rs10089 1.000 rs13355233 chr5:127425350 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.55 -6.87 -0.35 3.02e-11 Ileal carcinoids; LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg09177884 chr7:1199841 ZFAND2A -0.41 -5.98 -0.31 5.61e-9 Longevity;Endometriosis; LIHC cis rs9309473 0.898 rs10201159 chr2:73858965 T/C cg20560298 chr2:73613845 ALMS1 -0.54 -6.4 -0.33 5.25e-10 Metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04232541 chr6:144384895 PLAGL1 0.45 6.68 0.34 9.7e-11 Cognitive function; LIHC cis rs7618501 0.602 rs2624853 chr3:50128893 A/G cg21467203 chr3:49911342 NA 0.44 7.83 0.39 6.17e-14 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg22528358 chr1:107598549 PRMT6 -0.67 -11.08 -0.51 1.4e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11958404 0.932 rs6865373 chr5:157436728 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs8117834 0.574 rs73076227 chr20:8081168 G/A cg00593689 chr4:53575888 NA 0.39 6.5 0.33 2.88e-10 Chronic kidney disease; LIHC trans rs877282 0.945 rs11599043 chr10:777972 C/T cg22713356 chr15:30763199 NA 1.31 12.35 0.56 3.28e-29 Uric acid levels; LIHC cis rs6754311 0.638 rs1011361 chr2:136553639 G/A cg25344623 chr2:136566232 LCT 0.43 8.46 0.42 8.01e-16 Mosquito bite size; LIHC cis rs12540874 0.698 rs12718574 chr7:50573848 G/C cg18232548 chr7:50535776 DDC -0.42 -6.36 -0.33 6.64e-10 Systemic sclerosis; LIHC cis rs4319547 0.695 rs6489002 chr12:122929822 T/C cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.51 -0.38 5.36e-13 Body mass index; LIHC trans rs11098499 1.000 rs1011054 chr4:120202387 A/G cg25214090 chr10:38739885 LOC399744 -0.47 -6.98 -0.35 1.54e-11 Corneal astigmatism; LIHC cis rs16958440 0.541 rs62095459 chr18:44621382 A/T cg17192377 chr18:44677553 HDHD2 0.5 6.31 0.32 8.73e-10 Sitting height ratio; LIHC cis rs7107174 1.000 rs10899455 chr11:77999163 T/C cg02023728 chr11:77925099 USP35 0.5 9.68 0.46 9.84e-20 Testicular germ cell tumor; LIHC cis rs4243830 1.000 rs12401795 chr1:6594773 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.88 9.29 0.45 1.82e-18 Body mass index; LIHC cis rs727505 1.000 rs2286175 chr7:124431032 G/A cg23710748 chr7:124431027 NA -0.37 -6.34 -0.32 7.11e-10 Lewy body disease; LIHC cis rs1005277 0.638 rs1005278 chr10:38218748 G/A cg00409905 chr10:38381863 ZNF37A 0.47 7.64 0.38 2.16e-13 Extrinsic epigenetic age acceleration; LIHC cis rs2108225 0.872 rs7792139 chr7:107445433 G/A cg18560240 chr7:107437656 SLC26A3 -0.55 -8.26 -0.41 3.16e-15 Ulcerative colitis; LIHC cis rs765787 0.530 rs4775822 chr15:45527127 A/G cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.78 -0.3 1.71e-8 Uric acid levels; LIHC cis rs10779751 1.000 rs7524202 chr1:11297762 T/C cg08854313 chr1:11322531 MTOR 0.8 11.24 0.52 3.72e-25 Body mass index; LIHC cis rs908922 0.676 rs549044 chr1:152514332 C/T cg20991723 chr1:152506922 NA 0.53 9.08 0.44 8.95e-18 Hair morphology; LIHC cis rs3820068 0.705 rs4645983 chr1:15850603 G/A cg17385448 chr1:15911702 AGMAT 0.37 6.39 0.33 5.28e-10 Systolic blood pressure; LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg21747090 chr2:27597821 SNX17 -0.46 -6.89 -0.35 2.71e-11 Menopause (age at onset); LIHC cis rs2404602 0.669 rs17464903 chr15:77195486 A/G cg03037974 chr15:76606532 NA 0.72 13.95 0.6 2.6e-35 Blood metabolite levels; LIHC cis rs4243830 0.571 rs60256927 chr1:6614747 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 0.98 12.02 0.55 5.2e-28 Body mass index; LIHC cis rs1707322 0.963 rs6666763 chr1:46436451 C/A cg03146154 chr1:46216737 IPP 0.48 7.77 0.39 9.34e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg08859206 chr1:53392774 SCP2 -0.38 -6.21 -0.32 1.56e-9 Monocyte count; LIHC cis rs4319547 0.656 rs1553179 chr12:122831073 A/G cg23029597 chr12:123009494 RSRC2 -0.53 -7.55 -0.38 4.11e-13 Body mass index; LIHC cis rs9381040 0.655 rs2268187 chr6:41042993 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.42 -6.62 -0.34 1.42e-10 Alzheimer's disease (late onset); LIHC cis rs12594515 1.000 rs6493172 chr15:45987213 T/G cg01629716 chr15:45996671 NA 0.52 9.51 0.46 3.62e-19 Waist circumference;Weight; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg03536881 chr19:49496987 RUVBL2;GYS1 -0.5 -6.07 -0.31 3.39e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs826838 1.000 rs11609286 chr12:38875511 A/G cg13010199 chr12:38710504 ALG10B -0.6 -7.46 -0.37 7.36e-13 Heart rate; LIHC cis rs801193 0.844 rs2244022 chr7:66202430 A/G cg11764359 chr7:65958608 NA 0.58 8.65 0.42 2.02e-16 Aortic root size; LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC cis rs7309 0.810 rs11684253 chr2:162034536 G/T cg22496339 chr2:162101262 NA 0.8 13.55 0.59 8.5e-34 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs9814567 1.000 rs62271513 chr3:134298412 T/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.16 0.32 2.05e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg24209194 chr3:40518798 ZNF619 0.63 9.7 0.46 8.18e-20 Renal cell carcinoma; LIHC cis rs7592578 0.679 rs62181018 chr2:191323295 C/T cg10560079 chr2:191398806 TMEM194B -0.78 -11.23 -0.52 4e-25 Diastolic blood pressure; LIHC cis rs2576037 0.583 rs530205 chr18:44385150 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.84 -0.3 1.25e-8 Personality dimensions; LIHC cis rs12477438 0.501 rs13000731 chr2:99795231 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC trans rs5756813 0.754 rs3788529 chr22:38158709 A/G cg19894588 chr14:64061835 NA -0.64 -8.79 -0.43 7.65e-17 Optic cup area;Vertical cup-disc ratio; LIHC cis rs2637266 0.905 rs10824428 chr10:78346041 G/A cg18941641 chr10:78392320 NA 0.29 6.06 0.31 3.52e-9 Pulmonary function; LIHC cis rs7659604 0.540 rs7698889 chr4:122671324 G/T cg19671926 chr4:122722719 EXOSC9 0.46 6.76 0.34 6.06e-11 Type 2 diabetes; LIHC cis rs6088580 0.668 rs1205340 chr20:32923871 G/A cg08999081 chr20:33150536 PIGU -0.66 -12.6 -0.56 3.78e-30 Glomerular filtration rate (creatinine); LIHC cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.15 -0.55 1.74e-28 Alzheimer's disease; LIHC trans rs11098499 0.863 rs3775849 chr4:120450908 G/C cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg07384357 chr20:62499359 TPD52L2 0.38 6.13 0.31 2.38e-9 Myopia (pathological); LIHC cis rs3806843 0.735 rs2563314 chr5:140047289 A/G cg26395211 chr5:140044315 WDR55 0.4 5.88 0.3 9.85e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4865169 0.811 rs6841086 chr4:57903268 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.51 8.5 0.42 5.85e-16 Breast cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18002896 chr8:144465845 RHPN1 0.39 6.07 0.31 3.37e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.764 rs2247211 chr6:146216379 G/A cg05347473 chr6:146136440 FBXO30 0.35 5.71 0.3 2.43e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs800082 0.734 rs1527236 chr3:144246938 G/A cg24215973 chr2:240111563 HDAC4 0.44 6.43 0.33 4.33e-10 Smoking behavior; LIHC cis rs11122272 0.735 rs2808584 chr1:231512925 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs7927771 0.832 rs11601603 chr11:47401171 A/C cg20135002 chr11:47629003 NA -0.51 -8.59 -0.42 3.11e-16 Subjective well-being; LIHC cis rs11148252 0.904 rs7321964 chr13:53040822 A/G cg00495681 chr13:53174319 NA 0.41 6.83 0.35 3.79e-11 Lewy body disease; LIHC cis rs60871478 0.898 rs62432897 chr7:825429 A/G cg27478167 chr7:817139 HEATR2 -0.49 -6.73 -0.34 7.37e-11 Cerebrospinal P-tau181p levels; LIHC cis rs10751667 0.600 rs10751665 chr11:941300 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.87 -0.63 6.47e-39 Alzheimer's disease (late onset); LIHC cis rs1707322 0.721 rs61784800 chr1:46178112 A/G cg06784218 chr1:46089804 CCDC17 -0.4 -7.49 -0.38 6.04e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7534824 0.543 rs12569174 chr1:101386179 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.59 7.04 0.36 1.06e-11 Refractive astigmatism; LIHC cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg06238570 chr21:40685208 BRWD1 -0.53 -8.69 -0.43 1.56e-16 Cognitive function; LIHC cis rs2710642 0.545 rs1406002 chr2:62807091 A/C cg17519650 chr2:63277830 OTX1 0.41 6.36 0.33 6.57e-10 LDL cholesterol levels;LDL cholesterol; LIHC cis rs2637266 0.846 rs2583045 chr10:78412385 C/G cg18941641 chr10:78392320 NA -0.27 -5.91 -0.3 8.31e-9 Pulmonary function; LIHC trans rs7504990 0.722 rs35879011 chr18:50373124 G/A cg08535148 chr4:26321143 RBPJ 0.56 7.03 0.36 1.12e-11 Gallbladder cancer; LIHC cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg16926213 chr1:1841314 NA 0.32 5.94 0.31 6.98e-9 Body mass index; LIHC cis rs1552244 0.882 rs56332224 chr3:10037321 G/A cg08888203 chr3:10149979 C3orf24 0.49 6.12 0.31 2.59e-9 Alzheimer's disease; LIHC cis rs34779708 0.931 rs67976880 chr10:35372261 G/C cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1873147 0.861 rs2899687 chr15:63325548 C/T cg12160578 chr15:63334699 TPM1 -0.57 -8.04 -0.4 1.44e-14 Orofacial clefts; LIHC cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg17971929 chr21:40555470 PSMG1 -0.48 -7.24 -0.36 3.02e-12 Cognitive function; LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg21782813 chr7:2030301 MAD1L1 0.54 9.97 0.47 1.02e-20 Bipolar disorder and schizophrenia; LIHC cis rs2274273 0.773 rs8006525 chr14:55813394 T/G cg04306507 chr14:55594613 LGALS3 0.32 6.08 0.31 3.13e-9 Protein biomarker; LIHC cis rs96067 0.772 rs6664471 chr1:36606757 A/G cg24686825 chr1:36642396 MAP7D1 -0.35 -5.87 -0.3 1.06e-8 Corneal structure; LIHC cis rs12893668 0.572 rs11846404 chr14:104156108 C/G cg08213375 chr14:104286397 PPP1R13B 0.35 5.73 0.3 2.26e-8 Reticulocyte count; LIHC cis rs6963495 0.719 rs73190174 chr7:105161216 T/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs6952808 0.798 rs28970524 chr7:1927484 C/T cg04565464 chr8:145669602 NFKBIL2 0.38 6.05 0.31 3.76e-9 Bipolar disorder and schizophrenia; LIHC cis rs6860806 0.507 rs183898 chr5:131716902 C/G cg24060327 chr5:131705240 SLC22A5 0.79 12.39 0.56 2.34e-29 Breast cancer; LIHC cis rs2758596 1.000 rs2241111 chr1:156163718 T/C cg25208724 chr1:156163844 SLC25A44 0.76 7.59 0.38 2.98e-13 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs870825 0.616 rs2130393 chr4:185642335 T/C cg04058563 chr4:185651563 MLF1IP 0.77 7.79 0.39 8.15e-14 Blood protein levels; LIHC cis rs559928 0.606 rs11231726 chr11:63987339 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.85 8.44 0.42 9.05e-16 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs10206020 0.885 rs11886082 chr2:1576683 T/C cg01028140 chr2:1542097 TPO -0.42 -6.17 -0.32 1.92e-9 IgG glycosylation; LIHC cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg11062466 chr8:58055876 NA 0.4 5.91 0.3 8.29e-9 Developmental language disorder (linguistic errors); LIHC cis rs6963495 0.818 rs116457537 chr7:105152072 A/G cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs9611565 0.506 rs7364221 chr22:41650190 C/A cg06634786 chr22:41940651 POLR3H -0.5 -5.85 -0.3 1.16e-8 Vitiligo; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg06420487 chr17:61919686 SMARCD2 0.44 5.95 0.31 6.71e-9 Height; LIHC cis rs238295 0.805 rs6053499 chr20:5542546 C/T cg24001556 chr20:5591874 RP5-1022P6.2 -0.47 -6.53 -0.33 2.43e-10 Occipital cortical area (total cortical area interaction); LIHC cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.84 -0.54 2.51e-27 Alzheimer's disease; LIHC cis rs3096299 0.685 rs2911244 chr16:89521860 A/G cg06640241 chr16:89574553 SPG7 0.82 15.06 0.63 1.08e-39 Multiple myeloma (IgH translocation); LIHC cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg05564831 chr3:52568323 NT5DC2 0.37 6.04 0.31 3.93e-9 Bipolar disorder; LIHC cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg25897951 chr4:1244024 CTBP1;C4orf42 0.41 5.84 0.3 1.19e-8 Longevity; LIHC cis rs7662987 0.517 rs2602881 chr4:100040695 A/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs11031096 0.754 rs10742242 chr11:4156851 T/C cg18678763 chr11:4115507 RRM1 -0.53 -8.16 -0.4 6.29e-15 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs4788570 0.510 rs9931074 chr16:71667680 C/T cg06353428 chr16:71660113 MARVELD3 1.44 15.19 0.63 3.51e-40 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02037503 chr14:23540729 ACIN1 0.51 7.49 0.38 5.94e-13 Pancreatic cancer; LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.57 -10.82 -0.5 1.21e-23 Prudent dietary pattern; LIHC cis rs796364 0.806 rs203765 chr2:200903020 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -7.23 -0.36 3.27e-12 Schizophrenia; LIHC cis rs9902453 0.808 rs56216220 chr17:28209182 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 11.04 0.51 1.98e-24 Coffee consumption (cups per day); LIHC cis rs875971 0.862 rs709596 chr7:65825913 A/G cg18252515 chr7:66147081 NA -0.45 -6.47 -0.33 3.4e-10 Aortic root size; LIHC cis rs1728785 0.901 rs1728787 chr16:68593042 G/C cg02972257 chr16:68554789 NA -0.55 -6.21 -0.32 1.55e-9 Ulcerative colitis; LIHC cis rs15676 0.783 rs2417126 chr9:131562457 C/T cg00228799 chr9:131580591 ENDOG -0.47 -6.72 -0.34 7.48e-11 Blood metabolite levels; LIHC cis rs796364 1.000 rs281763 chr2:200794870 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.16 0.44 4.71e-18 Schizophrenia; LIHC cis rs262150 0.819 rs6956589 chr7:158769301 C/T cg19418458 chr7:158789849 NA -0.37 -6.4 -0.33 4.98e-10 Facial morphology (factor 20); LIHC cis rs11098499 0.865 rs11098513 chr4:120316075 A/G cg09307838 chr4:120376055 NA 0.77 11.85 0.54 2.28e-27 Corneal astigmatism; LIHC cis rs2180341 0.695 rs6569487 chr6:127726196 C/T cg24812749 chr6:127587940 RNF146 -0.57 -8.64 -0.42 2.22e-16 Breast cancer; LIHC cis rs2303759 0.958 rs1465697 chr19:49837246 C/T cg22307029 chr19:49891270 CCDC155 0.56 8.92 0.43 2.92e-17 Multiple sclerosis; LIHC trans rs1005277 0.602 rs1780141 chr10:38504299 T/C cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs2895526 0.765 rs12413453 chr10:12722364 T/C cg00115178 chr10:12648176 CAMK1D -0.35 -6.2 -0.32 1.61e-9 Headache; LIHC cis rs10508774 1.000 rs10508774 chr10:32807861 A/G cg01819863 chr10:32635814 EPC1 0.65 6.03 0.31 4.19e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs561341 0.941 rs7215147 chr17:30266711 G/A cg20587970 chr11:113659929 NA -0.61 -7.22 -0.36 3.48e-12 Hip circumference adjusted for BMI; LIHC cis rs9303401 0.573 rs62081879 chr17:57181524 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.0 0.58 1.11e-31 Cognitive test performance; LIHC cis rs5769765 1.000 rs1033665 chr22:50252127 A/G cg26441486 chr22:50317300 CRELD2 0.35 6.12 0.31 2.59e-9 Schizophrenia; LIHC trans rs208520 0.545 rs10944874 chr6:66752080 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.86 -15.51 -0.64 1.93e-41 Exhaled nitric oxide output; LIHC cis rs3812111 0.677 rs1204846 chr6:116522021 C/A cg08036074 chr6:116424633 NT5DC1 -0.4 -6.46 -0.33 3.52e-10 Age-related macular degeneration; LIHC cis rs10876993 0.893 rs4760168 chr12:58087737 T/G cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -5.92 -0.3 7.82e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs8180040 0.676 rs66564457 chr3:47020072 G/A cg16586182 chr3:47516702 SCAP -0.48 -8.63 -0.42 2.31e-16 Colorectal cancer; LIHC cis rs4727027 0.933 rs6961605 chr7:148870108 G/A cg23583168 chr7:148888333 NA -0.71 -9.94 -0.47 1.33e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs8014204 0.967 rs4903266 chr14:75344941 C/G cg08847533 chr14:75593920 NEK9 -0.36 -5.97 -0.31 5.88e-9 Caffeine consumption; LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg04267008 chr7:1944627 MAD1L1 -0.69 -11.45 -0.53 6.37e-26 Bipolar disorder and schizophrenia; LIHC cis rs9896933 0.830 rs607544 chr17:80768760 C/G cg20578329 chr17:80767326 TBCD -0.72 -7.36 -0.37 1.4e-12 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15344021 chr17:2240169 TSR1;SGSM2 0.44 6.86 0.35 3.15e-11 Cognitive function; LIHC trans rs950169 0.579 rs12913054 chr15:84664456 A/G cg24036039 chr1:3397125 ARHGEF16 0.4 6.56 0.33 1.99e-10 Schizophrenia; LIHC cis rs904251 0.523 rs12202055 chr6:37486080 A/T cg01843034 chr6:37503916 NA -0.44 -7.25 -0.36 2.87e-12 Cognitive performance; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg12311636 chr6:118886798 C6orf204 -0.52 -6.23 -0.32 1.35e-9 Diastolic blood pressure; LIHC cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg11062466 chr8:58055876 NA 0.53 7.02 0.36 1.17e-11 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.735 rs10489611 chr1:231517854 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs2635047 0.967 rs2571001 chr18:44665083 C/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.47 6.17 0.32 1.9e-9 Educational attainment; LIHC cis rs1664789 0.683 rs702636 chr5:53268396 C/T ch.5.1024479R chr5:53302184 ARL15 0.46 7.2 0.36 3.98e-12 Waist circumference adjusted for body mass index; LIHC cis rs74544699 1.000 rs78267059 chr4:74798010 G/A cg02530824 chr4:74847766 PF4 0.66 6.8 0.35 4.61e-11 Growth-regulated protein alpha levels; LIHC cis rs9457247 0.765 rs6904946 chr6:167433948 C/T cg23791538 chr6:167370224 RNASET2 0.52 8.18 0.4 5.67e-15 Crohn's disease; LIHC cis rs9868809 0.772 rs12107418 chr3:48689787 A/G cg07636037 chr3:49044803 WDR6 -0.62 -7.41 -0.37 9.75e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs72781680 0.821 rs17045981 chr2:24109316 A/G cg08917208 chr2:24149416 ATAD2B 0.64 6.25 0.32 1.21e-9 Lymphocyte counts; LIHC cis rs11792861 0.926 rs7870597 chr9:111871864 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.64e-16 Menarche (age at onset); LIHC trans rs2479768 1.000 rs74041703 chr13:29587083 C/G cg08641024 chr16:47047688 NA 0.72 6.28 0.32 1.02e-9 Methotrexate phramacokinetics (acute lymphoblastic leukemia); LIHC cis rs3106136 0.814 rs6839224 chr4:95279214 A/C cg11021082 chr4:95130006 SMARCAD1 0.35 6.08 0.31 3.29e-9 Capecitabine sensitivity; LIHC cis rs12477438 0.520 rs11123763 chr2:99750673 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.24 0.61 1.91e-36 Chronic sinus infection; LIHC cis rs7647973 0.626 rs7637711 chr3:49829653 A/G cg03060546 chr3:49711283 APEH -0.59 -6.76 -0.34 6.11e-11 Menarche (age at onset); LIHC cis rs2153535 0.580 rs9392220 chr6:8457946 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs10857712 0.904 rs2265641 chr10:135221869 G/A cg19623624 chr10:135278901 LOC619207 0.42 6.52 0.33 2.55e-10 Systemic lupus erythematosus; LIHC cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg12311346 chr5:56204834 C5orf35 0.58 7.6 0.38 2.84e-13 Initial pursuit acceleration; LIHC cis rs12594515 0.967 rs11070465 chr15:45984899 A/G cg01629716 chr15:45996671 NA 0.52 9.56 0.46 2.42e-19 Waist circumference;Weight; LIHC cis rs4727027 0.901 rs4727018 chr7:148822247 G/C cg23583168 chr7:148888333 NA -0.73 -10.37 -0.49 4.37e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6500602 0.927 rs7200817 chr16:4480598 G/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.4 5.72 0.3 2.37e-8 Schizophrenia; LIHC cis rs3099143 0.901 rs1813479 chr15:77168646 T/C cg21673338 chr15:77095150 SCAPER 0.48 7.68 0.38 1.7e-13 Recalcitrant atopic dermatitis; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg07677032 chr17:61819896 STRADA 0.44 6.44 0.33 4.01e-10 Prudent dietary pattern; LIHC cis rs3768617 0.510 rs6691755 chr1:183099821 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs908922 0.676 rs4845784 chr1:152494583 G/C cg23254163 chr1:152506842 NA 0.23 5.88 0.3 9.66e-9 Hair morphology; LIHC cis rs7917772 0.565 rs61869210 chr10:104437175 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.6 7.06 0.36 9.22e-12 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs3820068 0.603 rs67349836 chr1:15966176 T/C cg17385448 chr1:15911702 AGMAT 0.33 5.87 0.3 1.04e-8 Systolic blood pressure; LIHC cis rs6500602 0.964 rs13335685 chr16:4469284 T/C cg08645402 chr16:4508243 NA 0.38 7.0 0.35 1.38e-11 Schizophrenia; LIHC cis rs155076 1.000 rs155076 chr13:21870114 A/G cg11317459 chr13:21872234 NA -1.2 -12.68 -0.57 1.9e-30 White matter hyperintensity burden; LIHC trans rs13113518 0.812 rs11133385 chr4:56326652 G/A cg15358633 chr12:38710606 ALG10B 0.42 6.05 0.31 3.82e-9 Height; LIHC cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 11.28 0.52 2.56e-25 Platelet count; LIHC cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg06108461 chr20:60628389 TAF4 0.55 7.28 0.37 2.36e-12 Obesity-related traits; LIHC cis rs738321 0.658 rs5756916 chr22:38507047 G/A cg25457927 chr22:38595422 NA -0.33 -7.13 -0.36 5.95e-12 Breast cancer; LIHC cis rs7587476 0.765 rs2121284 chr2:215656260 T/C cg04530015 chr2:215796436 ABCA12 0.42 7.1 0.36 7.45e-12 Neuroblastoma; LIHC cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg09323728 chr8:95962352 TP53INP1 0.27 5.83 0.3 1.25e-8 Type 2 diabetes; LIHC cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg09222892 chr1:25734099 RHCE 0.48 8.88 0.43 3.86e-17 Erythrocyte sedimentation rate; LIHC cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg16434002 chr17:42200994 HDAC5 -0.48 -7.16 -0.36 4.87e-12 Total body bone mineral density; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg19517378 chr4:83932058 LIN54 -0.36 -6.33 -0.32 7.53e-10 Oropharynx cancer; LIHC cis rs1144333 0.655 rs76532097 chr1:76320759 G/C cg10523679 chr1:76189770 ACADM 0.48 6.85 0.35 3.55e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg11663144 chr21:46675770 NA 0.33 6.04 0.31 4.01e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1005277 0.579 rs1740735 chr10:38497777 A/C cg17830980 chr10:43048298 ZNF37B -0.5 -9.58 -0.46 2.04e-19 Extrinsic epigenetic age acceleration; LIHC cis rs72627123 0.530 rs79371463 chr14:74474856 T/A cg11191049 chr14:74485465 ENTPD5;C14orf45 0.61 5.73 0.3 2.19e-8 Morning vs. evening chronotype; LIHC cis rs2033711 0.870 rs1051500 chr19:58944402 A/G cg03735888 chr19:58951602 ZNF132 0.36 5.95 0.31 6.5e-9 Uric acid clearance; LIHC trans rs1814175 0.645 rs7395438 chr11:49877379 G/T cg15704280 chr7:45808275 SEPT13 -0.95 -19.73 -0.73 2.22e-58 Height; LIHC cis rs7089973 0.604 rs7920216 chr10:116611794 G/A cg23260525 chr10:116636907 FAM160B1 0.36 7.11 0.36 6.7e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs992157 0.764 rs2891079 chr2:219184691 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.21 0.48 1.51e-21 Colorectal cancer; LIHC cis rs7683537 0.887 rs4540092 chr4:185633546 A/G cg04058563 chr4:185651563 MLF1IP 0.7 7.36 0.37 1.36e-12 Systemic lupus erythematosus; LIHC cis rs1801251 0.574 rs2250660 chr2:233752551 G/C cg08000102 chr2:233561755 GIGYF2 -0.45 -6.15 -0.32 2.17e-9 Coronary artery disease; LIHC cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg22168489 chr12:122356033 WDR66 0.45 6.46 0.33 3.6e-10 Mean corpuscular volume; LIHC cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg15691649 chr6:25882328 NA 0.46 5.92 0.3 7.84e-9 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01141043 chr14:65007050 HSPA2 -0.52 -6.14 -0.32 2.33e-9 Systolic blood pressure; LIHC cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg16405210 chr4:1374714 KIAA1530 -0.88 -14.69 -0.62 3.37e-38 Longevity; LIHC cis rs6089829 1.000 rs6089828 chr20:61668998 C/T cg03213289 chr20:61660250 NA 0.51 8.97 0.44 1.94e-17 Prostate cancer (SNP x SNP interaction); LIHC trans rs116095464 0.558 rs61689490 chr5:224904 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs7129220 0.588 rs77092969 chr11:10116298 G/A cg01453529 chr11:10209919 SBF2 -0.39 -6.93 -0.35 2.13e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs6738485 0.507 rs66569888 chr2:106886967 G/A cg15412446 chr2:106886593 NA -0.8 -8.01 -0.4 1.81e-14 Pursuit maintenance gain;Pursuit maintenance gain in psychotic disorders; LIHC cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.65 0.38 2e-13 Intelligence (multi-trait analysis); LIHC cis rs12478296 1.000 rs55777943 chr2:243040686 T/C cg06360820 chr2:242988706 NA -0.95 -12.43 -0.56 1.54e-29 Obesity-related traits; LIHC cis rs7044106 0.537 rs10818474 chr9:123489964 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 7.08 0.36 8.21e-12 Hip circumference adjusted for BMI; LIHC cis rs875971 0.898 rs6977501 chr7:65693342 T/C cg18876405 chr7:65276391 NA -0.38 -6.73 -0.34 7.21e-11 Aortic root size; LIHC cis rs12586317 0.513 rs11156871 chr14:35481196 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.35 0.59 5.37e-33 Psoriasis; LIHC cis rs17253792 0.731 rs3736876 chr14:56120178 T/C cg01858014 chr14:56050164 KTN1 -0.71 -7.22 -0.36 3.38e-12 Putamen volume; LIHC cis rs11627756 0.958 rs4906238 chr14:103077702 G/A cg12046867 chr14:103022105 NA -0.38 -5.88 -0.3 9.97e-9 Mean platelet volume; LIHC cis rs3768617 0.706 rs11588675 chr1:182988052 C/T ch.1.3577855R chr1:183094577 LAMC1 0.49 7.93 0.39 3.1e-14 Fuchs's corneal dystrophy; LIHC cis rs34779708 0.931 rs7084196 chr10:35367161 T/C cg03585969 chr10:35415529 CREM 0.85 12.9 0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7914558 1.000 rs1926030 chr10:104855656 T/C cg15744005 chr10:104629667 AS3MT -0.38 -8.42 -0.41 1.04e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs8073060 0.586 rs4796101 chr17:33998593 C/T cg19694781 chr19:47549865 TMEM160 -1.23 -12.9 -0.57 2.61e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs11690935 0.959 rs7355594 chr2:172639448 G/T cg13550731 chr2:172543902 DYNC1I2 -0.94 -18.94 -0.72 3.09e-55 Schizophrenia; LIHC cis rs769267 0.859 rs2916076 chr19:19545990 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.84 0.3 1.22e-8 Tonsillectomy; LIHC cis rs7216064 1.000 rs7224923 chr17:65842265 T/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.38 -0.45 9.54e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg02782426 chr3:40428986 ENTPD3 0.34 6.14 0.32 2.24e-9 Renal cell carcinoma; LIHC cis rs1707322 0.721 rs4660314 chr1:46229885 T/C cg06784218 chr1:46089804 CCDC17 0.42 7.77 0.39 9.57e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2832191 0.791 rs2832186 chr21:30484151 A/C cg08807101 chr21:30365312 RNF160 -0.64 -10.17 -0.48 2.12e-21 Dental caries; LIHC cis rs1914816 1.000 rs2456072 chr15:76545844 A/G cg03037974 chr15:76606532 NA -0.56 -5.77 -0.3 1.81e-8 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs751728 1.000 rs11752297 chr6:33735154 G/C cg25922239 chr6:33757077 LEMD2 0.43 7.1 0.36 7.39e-12 Crohn's disease; LIHC cis rs11690935 1.000 rs34542126 chr2:172542705 C/T cg13550731 chr2:172543902 DYNC1I2 0.94 19.49 0.73 2.04e-57 Schizophrenia; LIHC trans rs6489882 0.902 rs1981556 chr12:113372961 C/G cg10175203 chr3:128143634 NA 0.38 6.19 0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC cis rs1198872 0.558 rs10929699 chr2:10918209 C/T cg15705551 chr2:10952987 PDIA6 0.72 10.27 0.49 9.49e-22 Cardiac Troponin-T levels; LIHC cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg08645402 chr16:4508243 NA 0.4 7.22 0.36 3.4e-12 Schizophrenia; LIHC cis rs13191362 1.000 rs13213408 chr6:162998049 A/T cg06582575 chr6:163149167 PACRG;PARK2 0.7 6.37 0.33 6.11e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs11098499 0.708 rs1546506 chr4:120241240 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.58 0.42 3.36e-16 Corneal astigmatism; LIHC cis rs796364 0.806 rs34381014 chr2:200916403 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs600806 0.893 rs370088 chr1:109858119 T/C cg16275483 chr1:110013120 SYPL2 -0.49 -6.11 -0.31 2.76e-9 Intelligence (multi-trait analysis); LIHC cis rs10832963 1.000 rs10128711 chr11:18632984 A/G cg20219074 chr11:18656078 SPTY2D1 0.82 13.39 0.59 3.61e-33 Breast cancer; LIHC cis rs2281845 0.929 rs2057579 chr1:201099275 T/C cg24849736 chr1:201084428 NA -0.37 -7.22 -0.36 3.41e-12 Permanent tooth development; LIHC cis rs924607 0.898 rs1697990 chr5:626278 A/G cg04476341 chr5:669733 TPPP -0.36 -8.59 -0.42 3.07e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4689592 0.503 rs3857180 chr4:7073899 T/G cg06697600 chr4:7070879 GRPEL1 0.64 9.44 0.45 6.17e-19 Monocyte percentage of white cells; LIHC cis rs2842992 0.789 rs4235925 chr6:160202860 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.22 0.55 9.47e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg10802521 chr3:52805072 NEK4 0.36 5.76 0.3 1.88e-8 Bipolar disorder; LIHC cis rs1144333 0.655 rs76175698 chr1:76454792 C/T cg10523679 chr1:76189770 ACADM 0.44 5.92 0.31 7.66e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs8067545 0.750 rs9897246 chr17:19965702 T/G cg13482628 chr17:19912719 NA 0.5 8.32 0.41 2.12e-15 Schizophrenia; LIHC cis rs7572733 0.534 rs1607375 chr2:198800387 C/T cg03934865 chr2:198174659 NA 0.46 6.79 0.34 5.08e-11 Dermatomyositis; LIHC trans rs4650994 0.524 rs2761465 chr1:178579404 G/T cg05059571 chr16:84539110 KIAA1609 0.43 7.12 0.36 6.44e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs35110281 0.774 rs9978811 chr21:44998683 C/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.66 -0.34 1.06e-10 Mean corpuscular volume; LIHC cis rs4721295 0.546 rs1637766 chr7:2204400 G/A cg00106254 chr7:1943704 MAD1L1 0.39 6.09 0.31 3.06e-9 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs11628318 0.853 rs28444760 chr14:103041148 A/G cg23461800 chr14:103021989 NA -0.5 -7.12 -0.36 6.6e-12 Platelet count; LIHC cis rs5753618 0.561 rs5753521 chr22:31638027 T/C cg07713946 chr22:31675144 LIMK2 -0.43 -7.84 -0.39 5.78e-14 Colorectal cancer; LIHC cis rs7617773 0.963 rs9822496 chr3:48181333 T/C cg11946769 chr3:48343235 NME6 0.56 7.79 0.39 8.33e-14 Coronary artery disease; LIHC cis rs317689 0.702 rs544696 chr12:69749939 T/C cg14784868 chr12:69753453 YEATS4 0.86 15.63 0.65 6.3e-42 Response to diuretic therapy; LIHC cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.12 -0.44 6.77e-18 Bipolar disorder; LIHC cis rs1799949 0.602 rs8176235 chr17:41219560 C/T cg10360323 chr17:41437877 NA 0.45 6.65 0.34 1.17e-10 Menopause (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16868751 chr10:96162146 TBC1D12 0.4 6.78 0.34 5.14e-11 Cognitive function; LIHC trans rs208520 0.690 rs851464 chr6:66839802 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.33 -0.41 1.94e-15 Exhaled nitric oxide output; LIHC trans rs2727020 0.553 rs7479975 chr11:49581964 C/G cg15704280 chr7:45808275 SEPT13 -0.98 -20.43 -0.74 3.41e-61 Coronary artery disease; LIHC trans rs17685 0.753 rs6951943 chr7:75772452 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1461503 0.868 rs10790543 chr11:122838311 A/C cg14473756 chr11:122847823 NA -0.37 -6.67 -0.34 1.02e-10 Menarche (age at onset); LIHC cis rs9457247 1.000 rs407515 chr6:167407544 G/C cg12798992 chr6:167411361 FGFR1OP 0.61 10.14 0.48 2.73e-21 Crohn's disease; LIHC cis rs3008870 1.000 rs1925411 chr1:67370292 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.96 16.53 0.67 1.52e-45 Lymphocyte percentage of white cells; LIHC cis rs473651 0.740 rs502349 chr2:239318389 C/T cg21699342 chr2:239360505 ASB1 0.32 6.16 0.32 2.01e-9 Multiple system atrophy; LIHC cis rs12478296 0.792 rs57482298 chr2:243011148 C/A cg05760424 chr2:242988095 NA -0.53 -7.14 -0.36 5.58e-12 Obesity-related traits; LIHC cis rs2842992 0.789 rs4709370 chr6:160210061 A/G cg11366901 chr6:160182831 ACAT2 0.91 15.0 0.63 1.91e-39 Age-related macular degeneration (geographic atrophy); LIHC cis rs950776 0.752 rs2869546 chr15:78907345 C/T cg06917634 chr15:78832804 PSMA4 -0.59 -8.19 -0.41 5.14e-15 Sudden cardiac arrest; LIHC cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.9 8.81 0.43 6.52e-17 Platelet count; LIHC cis rs67311347 1.000 rs951560 chr3:40463471 A/G cg13409248 chr3:40428643 ENTPD3 0.4 6.79 0.34 5.06e-11 Renal cell carcinoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00894870 chr1:19578612 MRTO4;KIAA0090 0.43 6.92 0.35 2.17e-11 Cognitive function; LIHC trans rs6952808 0.689 rs79950306 chr7:2022063 C/G cg04565464 chr8:145669602 NFKBIL2 0.43 7.21 0.36 3.73e-12 Bipolar disorder and schizophrenia; LIHC cis rs807669 0.525 rs9605955 chr22:19181557 C/T cg02655711 chr22:19163373 SLC25A1 0.34 5.75 0.3 1.94e-8 Metabolite levels; LIHC cis rs941873 0.772 rs7086293 chr10:81103247 T/C cg11057378 chr10:81107060 PPIF 0.35 5.77 0.3 1.77e-8 Height; LIHC cis rs9910055 0.529 rs425038 chr17:42182028 T/C cg19774624 chr17:42201019 HDAC5 0.49 6.09 0.31 3.01e-9 Total body bone mineral density; LIHC trans rs11098499 0.909 rs9759478 chr4:120367998 G/A cg25214090 chr10:38739885 LOC399744 0.61 10.05 0.48 5.51e-21 Corneal astigmatism; LIHC cis rs7264396 0.561 rs6060753 chr20:34598430 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -8.52 -0.42 5.16e-16 Total cholesterol levels; LIHC cis rs12079745 0.590 rs76692040 chr1:169295689 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.79 -7.15 -0.36 5.28e-12 QT interval; LIHC cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg21724239 chr8:58056113 NA 0.63 7.46 0.37 7.34e-13 Developmental language disorder (linguistic errors); LIHC cis rs7474896 0.537 rs1779068 chr10:38250785 G/A cg25427524 chr10:38739819 LOC399744 0.46 6.07 0.31 3.47e-9 Obesity (extreme); LIHC cis rs2412488 1.000 rs2090117 chr4:54300591 G/T cg22241045 chr4:54363911 LNX1 0.45 7.13 0.36 6.01e-12 DNA methylation (variation); LIHC cis rs7520050 1.000 rs785473 chr1:46516863 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.93 0.31 7.49e-9 Red blood cell count;Reticulocyte count; LIHC trans rs11039798 0.623 rs7294273 chr11:48705374 T/C cg15704280 chr7:45808275 SEPT13 0.61 6.99 0.35 1.44e-11 Axial length; LIHC cis rs28735056 1.000 rs56376220 chr18:77609462 C/T cg20368463 chr18:77673604 PQLC1 -0.39 -6.92 -0.35 2.28e-11 Schizophrenia; LIHC trans rs17685 0.753 rs10251863 chr7:75790192 T/C cg19862616 chr7:65841803 NCRNA00174 0.94 19.29 0.72 1.3e-56 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2727020 0.658 rs7120136 chr11:49384358 A/C cg03929089 chr4:120376271 NA -0.86 -16.25 -0.66 2.02e-44 Coronary artery disease; LIHC cis rs703842 1.000 rs11172344 chr12:58193448 T/C cg18357645 chr12:58087776 OS9 -0.44 -7.03 -0.36 1.12e-11 Multiple sclerosis; LIHC cis rs7762018 0.891 rs1981069 chr6:170148837 G/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.77 0.34 5.71e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs10089 1.000 rs1842006 chr5:127508687 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.5 6.17 0.32 1.92e-9 Ileal carcinoids; LIHC cis rs11711311 0.668 rs11718061 chr3:113341826 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.39 6.72 0.34 7.63e-11 IgG glycosylation; LIHC cis rs67311347 1.000 rs1466236 chr3:40462162 C/T cg09455208 chr3:40491958 NA 0.32 6.53 0.33 2.33e-10 Renal cell carcinoma; LIHC cis rs7927592 0.913 rs7102898 chr11:68328870 G/A cg01657329 chr11:68192670 LRP5 -0.48 -6.23 -0.32 1.33e-9 Total body bone mineral density; LIHC cis rs2637266 1.000 rs2395384 chr10:78335329 G/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.91e-9 Pulmonary function; LIHC cis rs2933343 0.661 rs2630259 chr3:128606322 C/T cg25356066 chr3:128598488 ACAD9 0.55 7.7 0.38 1.51e-13 IgG glycosylation; LIHC cis rs875971 0.545 rs6460298 chr7:65907770 T/C cg11764359 chr7:65958608 NA 0.58 8.22 0.41 4.2e-15 Aortic root size; LIHC cis rs57502260 0.764 rs7105218 chr11:68222461 C/A cg16797656 chr11:68205561 LRP5 0.59 8.18 0.4 5.52e-15 Total body bone mineral density (age 45-60); LIHC cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg22105103 chr4:187893119 NA 0.36 9.02 0.44 1.35e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs1005277 0.579 rs932538 chr10:38381314 T/C cg25427524 chr10:38739819 LOC399744 -0.68 -13.35 -0.59 5.14e-33 Extrinsic epigenetic age acceleration; LIHC cis rs7589728 0.563 rs75606549 chr2:88466069 T/C cg04511125 chr2:88470314 THNSL2 0.97 9.91 0.47 1.56e-20 Plasma clusterin levels; LIHC cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg14829360 chr17:73884958 NA -0.51 -7.46 -0.37 7.38e-13 Psoriasis; LIHC cis rs5769765 0.819 rs9616379 chr22:50312035 C/T cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs6088813 1.000 rs6142379 chr20:33999267 A/G cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC cis rs600806 0.815 rs10858094 chr1:109950858 T/C cg23091122 chr1:110024289 SYPL2 -0.47 -6.32 -0.32 8.39e-10 Intelligence (multi-trait analysis); LIHC cis rs950169 1.000 rs79318564 chr15:84786150 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 7.52 0.38 4.86e-13 Schizophrenia; LIHC cis rs796364 0.806 rs1509832 chr2:200874443 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 8.71 0.43 1.35e-16 Schizophrenia; LIHC cis rs4478037 0.822 rs9826234 chr3:33123832 A/C cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.03 -0.36 1.1e-11 Major depressive disorder; LIHC cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg06108461 chr20:60628389 TAF4 -0.6 -7.68 -0.38 1.69e-13 Obesity-related traits; LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg24955400 chr8:30352338 RBPMS 0.54 6.68 0.34 9.97e-11 Liver enzyme levels (alkaline phosphatase); LIHC trans rs3812049 0.784 rs7734927 chr5:127453735 T/A cg16011800 chr17:1958478 HIC1 -0.52 -7.39 -0.37 1.16e-12 Lymphocyte counts;Red cell distribution width; LIHC trans rs11098499 0.820 rs28578366 chr4:120536905 A/G cg25214090 chr10:38739885 LOC399744 -0.57 -9.17 -0.44 4.63e-18 Corneal astigmatism; LIHC cis rs9368481 0.729 rs10946881 chr6:26914611 C/T cg18867708 chr6:26865862 GUSBL1 0.54 8.11 0.4 9.31e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs921968 0.565 rs35594672 chr2:219589280 T/A cg02985541 chr2:219472218 PLCD4 -0.38 -6.66 -0.34 1.07e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3796352 0.892 rs58515094 chr3:52995575 C/T cg07884673 chr3:53033167 SFMBT1 0.9 6.59 0.34 1.65e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs922107 0.713 rs7532966 chr1:89955188 T/C cg15422784 chr1:90023713 LRRC8B 0.47 7.47 0.37 6.89e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs9611565 0.592 rs56021266 chr22:41756571 C/T cg03806693 chr22:41940476 POLR3H -1.06 -10.79 -0.5 1.51e-23 Vitiligo; LIHC cis rs2242116 0.793 rs9855938 chr3:46957298 G/A cg16586182 chr3:47516702 SCAP -0.39 -6.62 -0.34 1.4e-10 Birth weight; LIHC cis rs739401 0.869 rs395188 chr11:3072631 A/G cg25174290 chr11:3078921 CARS -0.49 -7.52 -0.38 4.81e-13 Longevity; LIHC cis rs11676348 0.935 rs2230054 chr2:219000310 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.43 -5.86 -0.3 1.09e-8 Ulcerative colitis; LIHC cis rs2559856 1.000 rs2559860 chr12:102087636 C/T cg12924262 chr12:102091054 CHPT1 0.52 8.38 0.41 1.39e-15 Blood protein levels; LIHC cis rs1395 0.744 rs11126932 chr2:27476282 G/A cg23587288 chr2:27483067 SLC30A3 -0.35 -6.64 -0.34 1.21e-10 Blood metabolite levels; LIHC cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg11764359 chr7:65958608 NA -0.58 -6.08 -0.31 3.14e-9 Diabetic kidney disease; LIHC cis rs10791097 0.765 rs4622274 chr11:130729486 C/T cg12179176 chr11:130786555 SNX19 0.73 11.28 0.52 2.57e-25 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg11890956 chr21:40555474 PSMG1 0.55 9.19 0.44 3.95e-18 Cognitive function; LIHC cis rs2836950 0.565 rs8134214 chr21:40542367 A/C cg06238570 chr21:40685208 BRWD1 -0.39 -6.37 -0.33 6.08e-10 Menarche (age at onset); LIHC cis rs12291225 0.546 rs12291662 chr11:14342949 T/C cg05501817 chr11:14380813 RRAS2 -0.44 -6.21 -0.32 1.54e-9 Sense of smell; LIHC cis rs9911578 0.933 rs11868348 chr17:57179238 C/T cg12560992 chr17:57184187 TRIM37 0.97 17.94 0.7 3.35e-51 Intelligence (multi-trait analysis); LIHC cis rs7733403 1 rs7733403 chr5:140154215 A/G cg26395211 chr5:140044315 WDR55 -0.42 -6.22 -0.32 1.42e-9 Schizophrenia; LIHC cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg23172400 chr8:95962367 TP53INP1 -0.36 -8.06 -0.4 1.32e-14 Type 2 diabetes; LIHC cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg03264133 chr6:25882463 NA 0.56 7.51 0.38 5.16e-13 Blood metabolite levels; LIHC cis rs1801251 1.000 rs13013142 chr2:233600606 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.48 0.53 4.9e-26 Coronary artery disease; LIHC cis rs7395581 0.918 rs10742799 chr11:47293702 T/C cg25783544 chr11:47291846 MADD 0.43 6.15 0.32 2.22e-9 HDL cholesterol; LIHC cis rs986417 0.540 rs10144415 chr14:61112667 G/C cg27398547 chr14:60952738 C14orf39 0.66 7.23 0.36 3.14e-12 Gut microbiota (bacterial taxa); LIHC cis rs861020 0.604 rs3766612 chr1:210020013 G/T cg09163369 chr1:210001066 C1orf107 -0.45 -5.8 -0.3 1.53e-8 Orofacial clefts; LIHC cis rs477692 1.000 rs522891 chr10:131430916 T/C cg05714579 chr10:131428358 MGMT -0.44 -7.09 -0.36 7.83e-12 Response to temozolomide; LIHC cis rs910316 0.763 rs175036 chr14:75464295 C/T cg11812906 chr14:75593930 NEK9 -0.74 -13.92 -0.6 3.33e-35 Height; LIHC cis rs12893668 0.703 rs729438 chr14:104092789 A/G cg24130564 chr14:104152367 KLC1 0.55 9.47 0.46 4.72e-19 Reticulocyte count; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg26774971 chr6:158994407 TMEM181 0.43 6.56 0.33 1.97e-10 Immature fraction of reticulocytes; LIHC cis rs8056893 0.686 rs4783558 chr16:68403966 A/G cg02226672 chr16:68398533 SMPD3 0.45 6.43 0.33 4.37e-10 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs28595532 0.545 rs55699931 chr4:119249835 G/A cg21605333 chr4:119757512 SEC24D 0.79 6.65 0.34 1.19e-10 Cannabis dependence symptom count; LIHC cis rs941408 0.515 rs759067 chr19:2775668 C/T cg06609049 chr19:2785107 THOP1 0.81 13.84 0.6 6.99e-35 Total cholesterol levels; LIHC cis rs3812831 0.669 rs382913 chr13:114928255 G/T cg06611532 chr13:114900021 NA 0.43 7.81 0.39 6.96e-14 Schizophrenia; LIHC cis rs3106136 0.934 rs17376404 chr4:95224046 T/A cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.94 -0.39 2.95e-14 Capecitabine sensitivity; LIHC cis rs8141529 0.748 rs6519766 chr22:29269991 A/G cg02153584 chr22:29168773 CCDC117 -0.52 -8.09 -0.4 1.06e-14 Lymphocyte counts; LIHC cis rs12477438 0.765 rs6722164 chr2:99561527 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.44 -0.49 2.4e-22 Chronic sinus infection; LIHC trans rs9388451 0.839 rs9321054 chr6:126079968 A/G cg05039488 chr6:79577232 IRAK1BP1 0.56 9.12 0.44 6.52e-18 Brugada syndrome; LIHC cis rs2439831 0.850 rs12440573 chr15:44108997 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.42 0.33 4.42e-10 Lung cancer in ever smokers; LIHC cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg07424592 chr7:64974309 NA 0.65 8.24 0.41 3.61e-15 Diabetic kidney disease; LIHC cis rs155076 0.938 rs261375 chr13:21871882 A/G cg14456004 chr13:21872349 NA 1.23 13.44 0.59 2.37e-33 White matter hyperintensity burden; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21981481 chr7:127011849 ZNF800 0.28 6.12 0.31 2.5e-9 Cognitive function; LIHC cis rs3784262 1.000 rs4369598 chr15:58318603 G/T cg12031962 chr15:58353849 ALDH1A2 -0.36 -6.88 -0.35 2.87e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs10504229 0.565 rs7010503 chr8:58147127 G/A cg11062466 chr8:58055876 NA 0.41 6.11 0.31 2.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs6545883 0.894 rs4672431 chr2:61519922 C/A cg14146966 chr2:61757674 XPO1 -0.43 -7.25 -0.37 2.76e-12 Tuberculosis; LIHC cis rs7914558 1.000 rs11191541 chr10:104824199 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.86 -0.43 4.39e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs34779708 0.897 rs7897827 chr10:35386237 C/T cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.59e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3741404 0.609 rs669913 chr11:63869879 A/G cg18225595 chr11:63971243 STIP1 0.45 7.28 0.37 2.28e-12 Platelet count; LIHC cis rs6754311 0.731 rs12988076 chr2:136569848 C/A cg07169764 chr2:136633963 MCM6 -0.66 -9.96 -0.47 1.11e-20 Mosquito bite size; LIHC cis rs9300255 0.596 rs10773002 chr12:123746961 A/T cg05973401 chr12:123451056 ABCB9 -0.41 -5.72 -0.3 2.35e-8 Neutrophil percentage of white cells; LIHC cis rs1949733 1.000 rs2688223 chr4:8471398 T/C cg11789530 chr4:8429930 ACOX3 0.79 11.5 0.53 4.28e-26 Response to antineoplastic agents; LIHC cis rs6445975 0.667 rs4681672 chr3:58230436 C/T cg23715586 chr3:58305044 RPP14 -0.35 -5.79 -0.3 1.56e-8 Systemic lupus erythematosus; LIHC cis rs5769765 0.908 rs9627800 chr22:50319351 T/C cg02269571 chr22:50332266 NA -0.66 -9.07 -0.44 9.22e-18 Schizophrenia; LIHC cis rs9486719 0.948 rs2472906 chr6:96875318 G/T cg06623918 chr6:96969491 KIAA0776 0.73 7.18 0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs2292096 0.850 rs66893025 chr1:200757200 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.46 -6.1 -0.31 2.84e-9 Epilepsy; LIHC cis rs9470366 0.816 rs4331968 chr6:36623243 A/T cg08179530 chr6:36648295 CDKN1A 0.54 6.71 0.34 8.3e-11 QRS duration; LIHC cis rs17818399 0.926 rs35350086 chr2:46834036 C/G cg02822958 chr2:46747628 ATP6V1E2 0.45 6.8 0.35 4.66e-11 Height; LIHC cis rs6001982 0.541 rs55746155 chr22:41049514 A/G cg14879645 chr22:41048474 NA 0.4 5.82 0.3 1.35e-8 Breast cancer; LIHC cis rs17401966 1.000 rs11576866 chr1:10414432 A/G cg15208524 chr1:10270712 KIF1B 0.47 6.7 0.34 8.72e-11 Hepatocellular carcinoma; LIHC cis rs12477438 0.765 rs9710648 chr2:99673129 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs2580764 0.515 rs4672005 chr2:55246551 C/T cg09592903 chr2:55203963 RTN4 -0.71 -13.37 -0.59 4.34e-33 Mean platelet volume; LIHC cis rs17376456 0.877 rs12153506 chr5:93360953 T/G cg25358565 chr5:93447407 FAM172A 1.1 10.04 0.48 5.77e-21 Diabetic retinopathy; LIHC cis rs10845606 1.000 rs10845605 chr12:12833468 T/C cg09462578 chr12:12878428 APOLD1 -0.77 -10.66 -0.5 4.12e-23 Systemic lupus erythematosus; LIHC cis rs372883 0.507 rs8132992 chr21:30750561 T/C cg24692254 chr21:30365293 RNF160 0.45 5.91 0.3 8.12e-9 Pancreatic cancer; LIHC cis rs748404 0.690 rs2924369 chr15:43777985 G/A cg27015174 chr15:43622946 ADAL;LCMT2 -0.46 -7.85 -0.39 5.57e-14 Lung cancer; LIHC cis rs3809566 0.963 rs12148057 chr15:63331509 A/T cg12160578 chr15:63334699 TPM1 -0.6 -8.66 -0.42 1.93e-16 Platelet count; LIHC cis rs9902453 0.765 rs1531553 chr17:28066752 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.47 -0.59 1.77e-33 Coffee consumption (cups per day); LIHC cis rs2839186 0.770 rs2839984 chr21:47671690 A/G cg13012494 chr21:47604986 C21orf56 0.39 6.09 0.31 3.11e-9 Testicular germ cell tumor; LIHC cis rs2806561 0.964 rs1757041 chr1:23506063 G/A cg12483005 chr1:23474871 LUZP1 0.34 5.76 0.3 1.89e-8 Height; LIHC cis rs11628318 0.614 rs10140498 chr14:103154191 A/G cg01864069 chr14:103024347 NA 0.44 6.85 0.35 3.37e-11 Platelet count; LIHC cis rs7677751 0.806 rs67432867 chr4:55104454 A/T cg17187183 chr4:55093834 PDGFRA 0.67 8.61 0.42 2.8e-16 Corneal astigmatism; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg12419862 chr22:24373484 LOC391322 -0.73 -11.05 -0.51 1.74e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs769267 0.930 rs7254748 chr19:19397479 A/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.14e-9 Tonsillectomy; LIHC cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg08132940 chr7:1081526 C7orf50 -0.79 -6.72 -0.34 7.83e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8114671 0.662 rs6088664 chr20:33551100 G/A cg07148914 chr20:33460835 GGT7 0.63 9.68 0.46 9.9e-20 Height; LIHC cis rs4819052 0.851 rs1999335 chr21:46670613 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.02 0.51 2.34e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs875971 0.862 rs6460302 chr7:65960257 C/G cg18876405 chr7:65276391 NA 0.36 6.5 0.33 2.91e-10 Aortic root size; LIHC cis rs68170813 0.521 rs75035695 chr7:106818731 T/C cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs2153535 0.580 rs7453115 chr6:8447261 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.03 0.4 1.61e-14 Motion sickness; LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.46 7.33 0.37 1.69e-12 Prudent dietary pattern; LIHC cis rs7944584 0.502 rs10769256 chr11:47378396 C/T cg20307385 chr11:47447363 PSMC3 0.93 14.83 0.63 8.72e-39 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs12908161 1.000 rs12908549 chr15:85322351 C/G cg17507749 chr15:85114479 UBE2QP1 0.63 7.18 0.36 4.38e-12 Schizophrenia; LIHC cis rs8180040 0.845 rs295441 chr3:47333295 T/A cg16586182 chr3:47516702 SCAP -0.55 -9.99 -0.48 8.46e-21 Colorectal cancer; LIHC cis rs3806843 1.000 rs13184940 chr5:140172918 T/C cg26395211 chr5:140044315 WDR55 -0.43 -6.43 -0.33 4.19e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg10802521 chr3:52805072 NEK4 -0.44 -7.25 -0.37 2.75e-12 Bipolar disorder; LIHC cis rs986417 0.901 rs1955696 chr14:61028271 A/G cg27398547 chr14:60952738 C14orf39 0.75 8.69 0.43 1.57e-16 Gut microbiota (bacterial taxa); LIHC cis rs875971 1.000 rs12533997 chr7:65965377 A/G cg11764359 chr7:65958608 NA 0.91 16.81 0.67 1.25e-46 Aortic root size; LIHC cis rs1983891 0.955 rs7753653 chr6:41548430 C/T cg20194872 chr6:41519635 FOXP4 -0.4 -6.36 -0.33 6.37e-10 Prostate cancer; LIHC cis rs10106298 0.846 rs2099408 chr8:103680416 A/C cg10187029 chr8:103597600 NA 0.43 5.78 0.3 1.69e-8 Schizophrenia; LIHC cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.74e-10 Diabetic kidney disease; LIHC cis rs67460515 0.563 rs13256 chr3:160796505 G/A cg03342759 chr3:160939853 NMD3 -0.57 -8.05 -0.4 1.42e-14 Parkinson's disease; LIHC cis rs4906332 1.000 rs2065018 chr14:103879187 C/T cg19000871 chr14:103996768 TRMT61A 0.46 7.94 0.39 2.92e-14 Coronary artery disease; LIHC cis rs7772486 0.558 rs9376965 chr6:146130055 G/A cg23711669 chr6:146136114 FBXO30 0.64 9.87 0.47 2.28e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs796364 0.806 rs34582889 chr2:201010527 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.54 -6.15 -0.32 2.16e-9 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20488757 chr11:16760048 C11orf58 -0.49 -6.11 -0.31 2.71e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7020830 0.867 rs1472169 chr9:37209396 C/T cg14294708 chr9:37120828 ZCCHC7 1.15 24.58 0.8 1.38e-77 Schizophrenia; LIHC cis rs11098499 0.779 rs80242894 chr4:120375752 G/A cg09307838 chr4:120376055 NA 0.77 11.81 0.54 3.27e-27 Corneal astigmatism; LIHC cis rs666930 0.519 rs477992 chr1:120257576 A/G cg19096424 chr1:120255104 PHGDH 0.95 12.71 0.57 1.45e-30 Breast cancer; LIHC cis rs16828019 0.777 rs12047657 chr1:41461513 G/C cg03962019 chr1:41807865 NA 0.53 7.01 0.35 1.26e-11 Intelligence (multi-trait analysis); LIHC cis rs9733 0.526 rs6587542 chr1:150907701 G/T cg18016565 chr1:150552671 MCL1 0.5 9.51 0.46 3.62e-19 Tonsillectomy; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 8.89e-15 Prudent dietary pattern; LIHC cis rs10463316 0.894 rs13361298 chr5:150765549 T/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.04e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7647973 0.710 rs6797299 chr3:49609794 G/T cg03060546 chr3:49711283 APEH 0.62 6.96 0.35 1.76e-11 Menarche (age at onset); LIHC cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg03264133 chr6:25882463 NA 0.38 5.77 0.3 1.81e-8 Height; LIHC cis rs919433 0.679 rs7600862 chr2:198534514 C/T cg10820045 chr2:198174542 NA 0.46 7.13 0.36 5.93e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs35110281 0.776 rs9983763 chr21:44990578 A/G cg21573476 chr21:45109991 RRP1B 0.57 10.86 0.51 8.4e-24 Mean corpuscular volume; LIHC cis rs4450131 0.618 rs3781458 chr10:126343931 C/T cg20435097 chr10:126320824 FAM53B -0.61 -11.55 -0.53 2.87e-26 White blood cell count (basophil); LIHC cis rs1707322 1.000 rs10890376 chr1:46406582 C/T cg06784218 chr1:46089804 CCDC17 0.37 6.47 0.33 3.48e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17685 0.712 rs59659102 chr7:75710114 G/A cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.89e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2243480 1.000 rs906134 chr7:65444288 G/C cg10756647 chr7:56101905 PSPH 1.11 13.47 0.59 1.75e-33 Diabetic kidney disease; LIHC cis rs10751667 0.643 rs12278229 chr11:946985 A/G cg10932868 chr11:921992 NA 0.36 6.81 0.35 4.31e-11 Alzheimer's disease (late onset); LIHC trans rs9929218 0.953 rs11075696 chr16:68731365 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.67 -9.98 -0.47 9.02e-21 Colorectal cancer; LIHC cis rs9733 0.596 rs3087960 chr1:150620569 C/G cg15448220 chr1:150897856 SETDB1 0.4 6.32 0.32 8.39e-10 Tonsillectomy; LIHC trans rs7246657 0.882 rs13345148 chr19:37819631 A/G cg10208301 chr11:6592745 DNHD1 0.47 6.68 0.34 9.89e-11 Coronary artery calcification; LIHC cis rs7927592 0.717 rs7126451 chr11:68257386 A/G cg01657329 chr11:68192670 LRP5 0.45 6.47 0.33 3.42e-10 Total body bone mineral density; LIHC cis rs1775715 0.678 rs2778649 chr10:32146803 C/G cg14930904 chr10:32216787 ARHGAP12 0.35 6.01 0.31 4.87e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs8062405 0.755 rs62034355 chr16:28581038 G/C cg16576597 chr16:28551801 NUPR1 0.47 7.15 0.36 5.35e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7551222 0.681 rs4252686 chr1:204496895 A/G cg20240347 chr1:204465584 NA -0.36 -7.5 -0.38 5.47e-13 Schizophrenia; LIHC cis rs10791097 0.694 rs11222370 chr11:130744767 T/G cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs262150 0.851 rs2730249 chr7:158767628 A/G cg27247782 chr7:158767135 NA 0.28 5.73 0.3 2.2e-8 Facial morphology (factor 20); LIHC cis rs4595586 0.525 rs7972595 chr12:39338000 G/A cg26384229 chr12:38710491 ALG10B 0.53 6.35 0.32 6.99e-10 Morning vs. evening chronotype; LIHC cis rs796364 0.616 rs7589545 chr2:200676102 T/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.15 0.32 2.21e-9 Schizophrenia; LIHC cis rs2806561 1.000 rs1571466 chr1:23449183 T/C cg19743168 chr1:23544995 NA 0.4 7.66 0.38 1.95e-13 Height; LIHC cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg05564831 chr3:52568323 NT5DC2 0.37 5.9 0.3 8.86e-9 Bipolar disorder; LIHC cis rs9583531 0.600 rs7984468 chr13:111362093 C/A cg15841412 chr13:111365552 ING1 0.47 5.87 0.3 1.04e-8 Coronary artery disease; LIHC trans rs561341 0.843 rs879944 chr17:30242803 A/G cg20587970 chr11:113659929 NA -0.58 -6.95 -0.35 1.87e-11 Hip circumference adjusted for BMI; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11055926 chr10:111683227 XPNPEP1 0.46 6.29 0.32 9.86e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7618501 0.633 rs2353579 chr3:50027774 C/T cg24110177 chr3:50126178 RBM5 -0.47 -7.68 -0.38 1.64e-13 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg18252515 chr7:66147081 NA 1.29 17.4 0.69 4.95e-49 Diabetic kidney disease; LIHC cis rs6952808 0.965 rs11768541 chr7:1894884 G/A cg21782813 chr7:2030301 MAD1L1 0.44 7.12 0.36 6.28e-12 Bipolar disorder and schizophrenia; LIHC cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg10802521 chr3:52805072 NEK4 -0.39 -6.52 -0.33 2.59e-10 Electroencephalogram traits; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg09992215 chr4:57370492 ARL9 0.39 6.28 0.32 1e-9 Oropharynx cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03710481 chr6:122931605 PKIB 0.5 6.53 0.33 2.41e-10 Lung function (FEV1/FVC); LIHC cis rs11018874 0.532 rs11018867 chr11:89862345 C/T cg23743573 chr11:89867420 NAALAD2 0.39 5.99 0.31 5.37e-9 White blood cell types; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.71 0.76 2.62e-66 Height; LIHC cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg07061783 chr6:25882402 NA -0.47 -6.53 -0.33 2.38e-10 Blood metabolite levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg09009506 chr2:28216851 BRE -0.3 -6.05 -0.31 3.75e-9 Calcium levels; LIHC cis rs59698941 0.943 rs73259116 chr5:132218461 A/G cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs2732480 0.500 rs11168464 chr12:48602115 C/T cg21466736 chr12:48725269 NA -0.71 -10.95 -0.51 4.12e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs116095464 0.510 rs55750776 chr5:230467 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs9457247 0.935 rs427824 chr6:167403918 T/G cg12798992 chr6:167411361 FGFR1OP 0.53 8.25 0.41 3.48e-15 Crohn's disease; LIHC cis rs2180341 1.000 rs6569483 chr6:127658855 G/A cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs10504229 0.679 rs4738574 chr8:58033771 T/C cg02290350 chr8:58132656 NA 0.31 7.17 0.36 4.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs10197940 0.624 rs6724796 chr2:152412813 C/T cg06191203 chr2:152266755 RIF1 -0.52 -9.29 -0.45 1.82e-18 Lung cancer; LIHC cis rs7614311 0.689 rs73120898 chr3:63828780 G/A cg22134162 chr3:63841271 THOC7 -0.57 -6.57 -0.33 1.84e-10 Lung function (FVC);Lung function (FEV1); LIHC cis rs2932538 0.961 rs4839257 chr1:113219388 A/T cg22162597 chr1:113214053 CAPZA1 -0.65 -10.19 -0.48 1.86e-21 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs1005277 0.579 rs1780138 chr10:38501654 A/G cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs870825 0.587 rs58332461 chr4:185639742 G/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs6964587 0.869 rs55811257 chr7:91484799 T/A cg17063962 chr7:91808500 NA -0.94 -18.12 -0.7 6.66e-52 Breast cancer; LIHC cis rs4906332 0.782 rs2236281 chr14:104000518 G/T cg04998671 chr14:104000505 TRMT61A -0.58 -7.6 -0.38 2.93e-13 Coronary artery disease; LIHC cis rs6545883 0.791 rs4672445 chr2:61655008 T/C cg15711740 chr2:61764176 XPO1 0.43 6.03 0.31 4.14e-9 Tuberculosis; LIHC cis rs9814567 1.000 rs9829092 chr3:134229866 C/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.39 -5.76 -0.3 1.88e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs6489882 0.703 rs10850092 chr12:113359703 C/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs589448 0.933 rs523398 chr12:69752775 C/T cg22834771 chr12:69754056 YEATS4 -0.54 -9.55 -0.46 2.62e-19 Cerebrospinal fluid biomarker levels; LIHC cis rs7845219 0.544 rs9643352 chr8:95918288 C/T cg16049864 chr8:95962084 TP53INP1 -0.43 -6.43 -0.33 4.27e-10 Type 2 diabetes; LIHC cis rs7116495 1.000 rs2298457 chr11:71734211 T/C cg10381502 chr11:71823885 C11orf51 -0.54 -5.78 -0.3 1.73e-8 Severe influenza A (H1N1) infection; LIHC cis rs3096299 0.967 rs28689480 chr16:89460093 T/C cg08822215 chr16:89438651 ANKRD11 -0.42 -6.53 -0.33 2.31e-10 Multiple myeloma (IgH translocation); LIHC cis rs600806 0.888 rs3879450 chr1:109909149 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs1008375 0.932 rs6449321 chr4:17644472 A/G cg16339924 chr4:17578868 LAP3 0.41 5.83 0.3 1.25e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs67311347 1.000 rs7636719 chr3:40432084 C/T cg09455208 chr3:40491958 NA 0.35 6.97 0.35 1.65e-11 Renal cell carcinoma; LIHC trans rs11638815 0.581 rs783535 chr15:83250425 T/A cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.05 -0.31 3.78e-9 Lipoprotein-associated phospholipase A2 activity change in response to statin therapy; LIHC cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg27286337 chr10:134555280 INPP5A 0.92 12.54 0.56 6.11e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4888262 0.508 rs4887779 chr16:74647795 A/G cg01733217 chr16:74700730 RFWD3 -0.84 -16.51 -0.67 1.83e-45 Testicular germ cell tumor; LIHC cis rs4268898 0.552 rs6754391 chr2:24369019 C/T cg06627628 chr2:24431161 ITSN2 -0.47 -6.77 -0.34 5.62e-11 Asthma; LIHC cis rs6547741 0.935 rs12615690 chr2:27851120 T/C cg27432699 chr2:27873401 GPN1 0.78 12.72 0.57 1.34e-30 Oral cavity cancer; LIHC cis rs17102423 0.806 rs2411994 chr14:65590537 A/G cg16583315 chr14:65563665 MAX 0.4 8.09 0.4 1.07e-14 Obesity-related traits; LIHC cis rs9322193 0.847 rs4870054 chr6:150169538 C/T cg07701084 chr6:150067640 NUP43 0.3 6.11 0.31 2.69e-9 Lung cancer; LIHC cis rs2834256 0.847 rs11702148 chr21:35089712 G/T cg14850771 chr21:34775459 IFNGR2 0.42 6.35 0.32 6.91e-10 Red cell distribution width; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16247931 chr14:102771650 RAGE -0.41 -6.1 -0.31 2.89e-9 Cognitive function; LIHC cis rs763121 0.853 rs6001185 chr22:39052155 G/A cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs3740540 0.530 rs2362506 chr10:126290751 C/G cg04949429 chr10:126290192 LHPP 0.45 7.3 0.37 2.01e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs2439831 0.867 rs28729853 chr15:43673680 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.92 17.19 0.68 3.73e-48 Lung cancer in ever smokers; LIHC cis rs11690935 0.632 rs12991740 chr2:172885996 C/T cg13550731 chr2:172543902 DYNC1I2 0.67 11.81 0.54 3.1e-27 Schizophrenia; LIHC cis rs6089584 0.706 rs6089625 chr20:60620622 T/C cg06108461 chr20:60628389 TAF4 -1.0 -17.6 -0.69 7.78e-50 Body mass index; LIHC cis rs10089 1.000 rs4835944 chr5:127490870 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.54 -6.57 -0.33 1.84e-10 Ileal carcinoids; LIHC cis rs921968 0.541 rs12619347 chr2:219419935 T/C cg02176678 chr2:219576539 TTLL4 -0.57 -7.86 -0.39 5.01e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs11602339 1 rs11602339 chr11:47761471 C/T cg20307385 chr11:47447363 PSMC3 -0.44 -5.8 -0.3 1.55e-8 Body mass index; LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs11785400 1.000 rs3735999 chr8:143746069 T/C cg10596483 chr8:143751796 JRK 0.5 8.19 0.41 5.12e-15 Schizophrenia; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.3e-14 Height; LIHC trans rs1814175 0.645 rs1851857 chr11:49855589 A/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.48e-59 Height; LIHC cis rs1005277 0.579 rs1740747 chr10:38520465 G/A cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs16828019 0.704 rs12024115 chr1:41534357 C/T cg03962019 chr1:41807865 NA 0.49 7.18 0.36 4.45e-12 Intelligence (multi-trait analysis); LIHC cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg24642844 chr7:1081250 C7orf50 -0.64 -6.54 -0.33 2.31e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10752881 1.000 rs10797807 chr1:182978873 T/C ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs9790314 1.000 rs1382428 chr3:161032386 A/C cg04691961 chr3:161091175 C3orf57 -0.42 -6.53 -0.33 2.34e-10 Morning vs. evening chronotype; LIHC cis rs79149102 0.649 rs75985113 chr15:75379312 C/T cg09165964 chr15:75287851 SCAMP5 -0.61 -7.74 -0.39 1.15e-13 Lung cancer; LIHC cis rs12765878 1.000 rs2273698 chr10:105649158 G/A cg11005552 chr10:105648138 OBFC1 0.37 5.86 0.3 1.12e-8 Coronary artery disease; LIHC cis rs6583826 0.538 rs11187076 chr10:94336963 G/A cg00519463 chr10:94352821 KIF11 -0.44 -6.27 -0.32 1.11e-9 Type 2 diabetes; LIHC cis rs11626933 1.000 rs45463097 chr14:90744188 G/A cg14092571 chr14:90743983 NA -0.89 -14.33 -0.61 8.09e-37 Gut microbiota (bacterial taxa); LIHC cis rs2576037 0.562 rs477826 chr18:44397649 A/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.09 -0.36 7.66e-12 Personality dimensions; LIHC cis rs116095464 0.510 rs55750776 chr5:230467 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs10870270 0.956 rs4880405 chr10:133787021 G/A cg08754478 chr10:133766260 PPP2R2D -0.51 -7.43 -0.37 8.97e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg02290350 chr8:58132656 NA 0.48 9.3 0.45 1.78e-18 Developmental language disorder (linguistic errors); LIHC cis rs77741769 0.529 rs3901854 chr12:121225526 C/T cg02419362 chr12:121203948 SPPL3 0.33 5.71 0.3 2.42e-8 Mean corpuscular volume; LIHC cis rs6840360 0.837 rs13138986 chr4:152719310 T/C cg22705602 chr4:152727874 NA 0.34 7.03 0.36 1.14e-11 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.931 rs7430501 chr3:48890119 C/T cg06212747 chr3:49208901 KLHDC8B 0.55 7.12 0.36 6.57e-12 Parkinson's disease; LIHC cis rs9457247 1.000 rs400063 chr6:167386592 C/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.78 0.47 4.38e-20 Crohn's disease; LIHC cis rs1023500 0.596 rs5751204 chr22:42433801 C/T cg00645731 chr22:42541494 CYP2D7P1 0.41 6.31 0.32 8.55e-10 Schizophrenia; LIHC cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg00656387 chr3:40428638 ENTPD3 0.41 6.66 0.34 1.12e-10 Renal cell carcinoma; LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg21724239 chr8:58056113 NA 0.56 7.39 0.37 1.1e-12 Developmental language disorder (linguistic errors); LIHC cis rs2239547 0.522 rs9844736 chr3:52931971 T/G cg18404041 chr3:52824283 ITIH1 0.44 6.06 0.31 3.53e-9 Schizophrenia; LIHC cis rs875971 0.862 rs10276077 chr7:65728411 A/G cg18876405 chr7:65276391 NA -0.35 -6.34 -0.32 7.25e-10 Aortic root size; LIHC cis rs7914558 1.000 rs8139 chr10:104848123 G/A cg15744005 chr10:104629667 AS3MT -0.37 -8.31 -0.41 2.26e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs13040088 0.872 rs13039291 chr20:61572760 C/T cg23096297 chr20:61557774 DIDO1 0.83 10.94 0.51 4.23e-24 Menopause (age at onset); LIHC cis rs988712 0.705 rs16917204 chr11:27668355 G/C cg18117895 chr11:27722066 BDNF 0.49 6.85 0.35 3.45e-11 Obesity; LIHC cis rs2243480 0.901 rs3813708 chr7:65305632 C/A cg05590025 chr7:65112418 INTS4L2 -0.6 -6.45 -0.33 3.93e-10 Diabetic kidney disease; LIHC cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg11301795 chr4:187892539 NA -0.27 -7.11 -0.36 6.9e-12 Lobe attachment (rater-scored or self-reported); LIHC trans rs9951602 0.512 rs9953258 chr18:76651199 A/C cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC cis rs9916302 0.904 rs4794807 chr17:37531718 T/A cg07936489 chr17:37558343 FBXL20 0.84 13.62 0.59 4.63e-34 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.49 0.38 5.79e-13 Prudent dietary pattern; LIHC trans rs1941687 0.505 rs12605642 chr18:31313965 G/T cg27147174 chr7:100797783 AP1S1 -0.47 -6.72 -0.34 7.49e-11 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC trans rs7618501 0.602 rs2245365 chr3:50097319 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.59 -9.64 -0.46 1.35e-19 Intelligence (multi-trait analysis); LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg21747090 chr2:27597821 SNX17 -0.4 -5.97 -0.31 5.96e-9 Menopause (age at onset); LIHC cis rs920590 0.796 rs7820520 chr8:19634864 A/G cg03894339 chr8:19674705 INTS10 -0.44 -6.42 -0.33 4.61e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs6942756 0.840 rs963465 chr7:128875612 C/G cg02491457 chr7:128862824 NA 0.64 10.32 0.49 6.42e-22 White matter hyperintensity burden; LIHC trans rs459571 1.000 rs456207 chr9:136911140 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.51 -7.81 -0.39 7.19e-14 Platelet distribution width; LIHC cis rs2153535 0.601 rs1855768 chr6:8472969 T/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs2072438 0.503 rs1323474 chr9:123852859 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.1 0.31 2.94e-9 Rheumatoid arthritis; LIHC cis rs34172651 0.517 rs2287783 chr16:24831727 C/T cg04756594 chr16:24857601 SLC5A11 0.62 9.06 0.44 1.04e-17 Intelligence (multi-trait analysis); LIHC cis rs17826219 0.636 rs2449770 chr17:29101064 G/T cg14067834 chr17:29058358 SUZ12P 0.72 7.12 0.36 6.39e-12 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21292957 chr21:34602922 IFNAR2 0.53 7.17 0.36 4.81e-12 Lung function (FEV1/FVC); LIHC cis rs2380220 0.808 rs2716069 chr6:95912976 C/G cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs7918232 0.882 rs2149413 chr10:27430311 C/T cg14442939 chr10:27389572 ANKRD26 -0.74 -7.06 -0.36 9.19e-12 Breast cancer; LIHC cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg18867708 chr6:26865862 GUSBL1 -0.5 -7.69 -0.38 1.59e-13 Schizophrenia; LIHC cis rs8017423 0.845 rs8005870 chr14:90723172 A/C cg14092571 chr14:90743983 NA -0.38 -5.98 -0.31 5.75e-9 Mortality in heart failure; LIHC cis rs7677751 0.767 rs6554158 chr4:55066077 G/A cg17187183 chr4:55093834 PDGFRA 0.58 7.33 0.37 1.66e-12 Corneal astigmatism; LIHC cis rs651907 0.557 rs11924013 chr3:101366698 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.87 0.57 3.53e-31 Colorectal cancer; LIHC cis rs6952808 0.531 rs4721441 chr7:2184060 A/G cg02951883 chr7:2050386 MAD1L1 -0.56 -9.04 -0.44 1.21e-17 Bipolar disorder and schizophrenia; LIHC cis rs10751667 1.000 rs10794349 chr11:945678 T/C cg10932868 chr11:921992 NA 0.35 6.65 0.34 1.16e-10 Alzheimer's disease (late onset); LIHC trans rs116095464 0.558 rs6874745 chr5:264527 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs7729447 0.566 rs1421811 chr5:32714270 C/G cg16267343 chr5:32710456 NPR3 0.45 5.8 0.3 1.53e-8 Blood pressure; LIHC cis rs9303401 0.659 rs12952325 chr17:56899371 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.89 11.88 0.54 1.73e-27 Cognitive test performance; LIHC cis rs7258465 0.965 rs271622 chr19:18629277 A/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.28 -0.37 2.34e-12 Breast cancer; LIHC cis rs6121246 0.529 rs6060195 chr20:30185638 C/T cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08944563 chr10:91174254 IFIT5 0.37 6.03 0.31 4.15e-9 Calcium levels; LIHC cis rs4268898 0.722 rs7564420 chr2:24414002 C/T cg06627628 chr2:24431161 ITSN2 -0.45 -6.5 -0.33 2.91e-10 Asthma; LIHC cis rs311392 0.871 rs402088 chr8:55092805 A/G cg11783602 chr8:55087084 NA -0.31 -6.23 -0.32 1.36e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs926392 0.799 rs742274 chr20:37680944 T/C cg16355469 chr20:37678765 NA 0.37 6.0 0.31 5.1e-9 Dialysis-related mortality; LIHC cis rs6546550 0.935 rs60207187 chr2:70093910 G/A cg02498382 chr2:70120550 SNRNP27 -0.38 -6.33 -0.32 7.6e-10 Prevalent atrial fibrillation; LIHC cis rs3617 0.625 rs2239548 chr3:52854186 A/C cg11645453 chr3:52864694 ITIH4 0.21 5.85 0.3 1.14e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs12493885 0.505 rs357489 chr3:153884517 A/T cg16511985 chr3:153974050 SGEF 0.28 6.1 0.31 2.88e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7503807 0.967 rs12940622 chr17:78615571 G/A cg09596252 chr17:78655493 RPTOR 0.4 7.06 0.36 9.53e-12 Obesity; LIHC trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg22968622 chr17:43663579 NA 1.17 12.88 0.57 3.24e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20297566 chr3:99979976 TBC1D23 0.48 6.47 0.33 3.36e-10 Lung function (FEV1/FVC); LIHC cis rs11971779 0.838 rs58074268 chr7:139108925 C/T cg07862535 chr7:139043722 LUC7L2 0.62 10.43 0.49 2.75e-22 Diisocyanate-induced asthma; LIHC cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg12042659 chr19:58951599 ZNF132 0.37 6.31 0.32 8.44e-10 Uric acid clearance; LIHC trans rs1945213 0.694 rs7106894 chr11:55877315 T/C cg15704280 chr7:45808275 SEPT13 0.61 7.98 0.4 2.29e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg13271783 chr10:134563150 INPP5A -0.6 -7.17 -0.36 4.71e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11098499 0.754 rs12506610 chr4:120241659 T/C cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs4689592 0.587 rs6825954 chr4:7074226 T/C cg06697600 chr4:7070879 GRPEL1 -0.66 -10.46 -0.49 2.12e-22 Monocyte percentage of white cells; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20959480 chr12:125599568 AACS 0.37 6.08 0.31 3.25e-9 Longevity; LIHC cis rs17253792 0.822 rs9972180 chr14:56073732 G/T cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs2806561 0.780 rs4655142 chr1:23333728 T/C cg19743168 chr1:23544995 NA -0.37 -6.9 -0.35 2.58e-11 Height; LIHC cis rs9616064 0.506 rs2073275 chr22:47070432 G/C cg05621596 chr22:47072043 GRAMD4 -0.76 -12.06 -0.55 3.83e-28 Urate levels in obese individuals; LIHC cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6977660 0.714 rs10252965 chr7:19822385 A/C cg07541023 chr7:19748670 TWISTNB 0.4 6.06 0.31 3.61e-9 Thyroid stimulating hormone; LIHC trans rs561341 1.000 rs111454793 chr17:30319267 T/C cg20587970 chr11:113659929 NA -1.39 -11.8 -0.54 3.55e-27 Hip circumference adjusted for BMI; LIHC cis rs9368481 0.594 rs7768814 chr6:26892036 C/A cg18867708 chr6:26865862 GUSBL1 0.56 8.5 0.42 5.94e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs2235642 0.928 rs9932984 chr16:1605051 A/G cg03034668 chr16:1723424 CRAMP1L -0.39 -6.84 -0.35 3.72e-11 Coronary artery disease; LIHC cis rs3762637 1.000 rs7609972 chr3:122199426 T/G cg24169773 chr3:122142474 KPNA1 -0.48 -9.53 -0.46 3.12e-19 LDL cholesterol levels; LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg20887711 chr4:1340912 KIAA1530 0.8 12.32 0.55 4.23e-29 Longevity; LIHC cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg19723775 chr5:179050963 HNRNPH1 0.59 9.87 0.47 2.25e-20 Lung cancer; LIHC cis rs4803468 1.000 rs284658 chr19:41929988 G/A cg09537434 chr19:41945824 ATP5SL -1.03 -21.3 -0.76 1.1e-64 Height; LIHC cis rs1577917 1.000 rs16876529 chr6:86591202 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -8.1 -0.4 9.48e-15 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs9328479 chr6:8519646 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.63 0.42 2.3e-16 Motion sickness; LIHC cis rs7100689 0.646 rs7092237 chr10:82165640 A/G cg00277334 chr10:82204260 NA -0.47 -7.07 -0.36 8.92e-12 Post bronchodilator FEV1; LIHC cis rs9326248 0.798 rs10892079 chr11:117016824 T/G cg11861562 chr11:117069780 TAGLN 0.45 7.4 0.37 1.07e-12 Blood protein levels; LIHC cis rs72634258 0.554 rs12723500 chr1:7857374 G/C cg00864860 chr1:7907996 UTS2 0.6 5.89 0.3 9.05e-9 Inflammatory bowel disease; LIHC cis rs910316 0.935 rs175422 chr14:75627319 T/A cg11812906 chr14:75593930 NEK9 -0.74 -14.17 -0.61 3.62e-36 Height; LIHC cis rs1691799 0.899 rs1168358 chr12:66748664 A/G cg16791601 chr12:66731901 HELB -0.52 -12.33 -0.55 3.91e-29 White blood cell count (basophil); LIHC cis rs1385374 0.858 rs11059926 chr12:129294244 A/T cg09035930 chr12:129282057 SLC15A4 -0.5 -5.89 -0.3 9.38e-9 Systemic lupus erythematosus; LIHC cis rs8072100 0.811 rs1912483 chr17:45443494 A/G cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.72 -0.3 2.34e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.88 -0.3 9.73e-9 Total body bone mineral density; LIHC cis rs6088580 0.524 rs6088567 chr20:33263872 A/T cg08999081 chr20:33150536 PIGU -0.43 -7.24 -0.36 2.89e-12 Glomerular filtration rate (creatinine); LIHC trans rs783540 0.967 rs17158390 chr15:83293028 A/G cg18393722 chr15:85113863 UBE2QP1 -0.37 -6.34 -0.32 7.22e-10 Schizophrenia; LIHC cis rs651907 0.535 rs13084113 chr3:101534039 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.68 11.3 0.52 2.3e-25 Colorectal cancer; LIHC cis rs9612 1.000 rs9612 chr19:44235517 A/G cg08581076 chr19:44259116 C19orf61 0.61 7.15 0.36 5.16e-12 Exhaled nitric oxide output; LIHC cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg05665937 chr4:1216051 CTBP1 0.39 6.18 0.32 1.83e-9 Obesity-related traits; LIHC cis rs9733 0.565 rs7524620 chr1:150616699 C/T cg17724175 chr1:150552817 MCL1 -0.48 -9.8 -0.47 3.92e-20 Tonsillectomy; LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.15 -0.4 7.14e-15 Lymphocyte counts; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg12962599 chr5:36607024 SLC1A3 0.34 6.24 0.32 1.29e-9 Calcium levels; LIHC cis rs2439831 0.850 rs28707214 chr15:44131623 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.69 0.43 1.58e-16 Lung cancer in ever smokers; LIHC trans rs4824093 0.610 rs7410534 chr22:50289925 C/T cg09872104 chr7:134855509 C7orf49 -0.8 -6.38 -0.33 5.59e-10 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs3736485 0.966 rs10775144 chr15:51891134 C/T cg08986416 chr15:51914746 DMXL2 -0.41 -6.18 -0.32 1.87e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2976388 0.533 rs12543368 chr8:143819450 T/C cg06565975 chr8:143823917 SLURP1 -0.45 -8.18 -0.4 5.82e-15 Urinary tract infection frequency; LIHC cis rs644148 0.785 rs2140111 chr19:44973019 A/C cg15540054 chr19:45004280 ZNF180 -0.77 -10.71 -0.5 2.88e-23 Personality dimensions; LIHC cis rs6456156 0.524 rs6934043 chr6:167466449 C/T cg12798992 chr6:167411361 FGFR1OP 0.42 6.61 0.34 1.48e-10 Primary biliary cholangitis; LIHC cis rs3849570 0.695 rs9830445 chr3:81508063 T/G cg07356753 chr3:81810745 GBE1 0.46 6.84 0.35 3.7e-11 Waist circumference;Body mass index; LIHC cis rs9649465 0.846 rs13044 chr7:123322716 T/A cg03229431 chr7:123269106 ASB15 -0.38 -8.07 -0.4 1.19e-14 Migraine; LIHC cis rs7772486 0.875 rs13198450 chr6:146370524 C/A cg23711669 chr6:146136114 FBXO30 0.67 12.08 0.55 3.21e-28 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20621256 chr9:140118465 C9orf169 0.49 7.01 0.35 1.27e-11 Pancreatic cancer; LIHC cis rs919433 0.617 rs4850436 chr2:198541398 C/T cg10820045 chr2:198174542 NA -0.5 -7.62 -0.38 2.45e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs208515 0.525 rs12214310 chr6:66666308 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.83 0.43 5.5e-17 Exhaled nitric oxide levels; LIHC cis rs798554 1.000 rs798548 chr7:2760935 A/G cg19346786 chr7:2764209 NA -0.46 -6.97 -0.35 1.61e-11 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg23556447 chr6:90529595 MDN1 -0.53 -7.24 -0.36 3.01e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7937890 0.531 rs2597216 chr11:14533916 G/A cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs7106204 0.534 rs7928616 chr11:24296060 T/C ch.11.24196551F chr11:24239977 NA 0.78 10.55 0.5 1.05e-22 Response to Homoharringtonine (cytotoxicity); LIHC cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 11.68 0.53 9.51e-27 Alzheimer's disease; LIHC cis rs208520 0.661 rs7740835 chr6:66865548 G/A cg07460842 chr6:66804631 NA -0.78 -8.54 -0.42 4.49e-16 Exhaled nitric oxide output; LIHC cis rs778371 0.624 rs6733495 chr2:233616709 A/G cg08000102 chr2:233561755 GIGYF2 0.88 14.68 0.62 3.68e-38 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05977900 chr3:182512126 ATP11B 0.45 6.34 0.32 7.4e-10 Pancreatic cancer; LIHC cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.14e-11 Alzheimer's disease; LIHC cis rs6545883 0.894 rs6545867 chr2:61651027 C/T cg15711740 chr2:61764176 XPO1 0.43 6.09 0.31 3.11e-9 Tuberculosis; LIHC cis rs9790314 0.690 rs6799130 chr3:160847801 C/G cg03342759 chr3:160939853 NMD3 -0.72 -11.07 -0.51 1.46e-24 Morning vs. evening chronotype; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19098793 chr7:1609793 KIAA1908;PSMG3 0.49 6.27 0.32 1.07e-9 Lung function (FEV1/FVC); LIHC cis rs2228479 0.717 rs34027607 chr16:89808939 T/C cg04013166 chr16:89971882 TCF25 0.47 6.02 0.31 4.48e-9 Skin colour saturation; LIHC cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg22105103 chr4:187893119 NA 0.3 7.26 0.37 2.63e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs5758511 0.680 rs5758684 chr22:42649509 C/T cg20195005 chr22:42527684 CYP2D6 0.31 5.88 0.3 1e-8 Birth weight; LIHC cis rs55882075 0.730 rs10794700 chr5:179148335 C/G cg14593053 chr5:179126677 CANX 0.45 8.18 0.4 5.6e-15 Monocyte percentage of white cells; LIHC cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg11062466 chr8:58055876 NA 0.4 5.91 0.3 8.29e-9 Developmental language disorder (linguistic errors); LIHC cis rs1165668 1.000 rs2583282 chr12:104313579 A/G cg21863207 chr12:104234989 NT5DC3 0.4 6.4 0.33 5.22e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs5758659 0.716 rs5758661 chr22:42624445 A/C cg19513890 chr22:42538836 CYP2D7P1 -0.31 -5.99 -0.31 5.25e-9 Cognitive function; LIHC cis rs910316 0.763 rs6574205 chr14:75453039 G/C cg11812906 chr14:75593930 NEK9 0.75 14.05 0.6 1.05e-35 Height; LIHC cis rs904251 0.523 rs9366935 chr6:37480404 C/T cg01843034 chr6:37503916 NA -0.47 -7.99 -0.4 2.12e-14 Cognitive performance; LIHC cis rs7131987 0.650 rs7301188 chr12:29455391 C/T cg12903224 chr12:29470962 FAR2 -0.4 -6.55 -0.33 2.1e-10 QT interval; LIHC cis rs651907 0.557 rs11924013 chr3:101366698 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.47 -6.74 -0.34 6.56e-11 Colorectal cancer; LIHC cis rs2455799 0.927 rs2470514 chr3:15750344 A/C cg12698662 chr3:15914712 MIR563 -0.41 -5.91 -0.3 8.44e-9 Mean platelet volume; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg21235925 chr17:80678270 FN3KRP 0.47 6.35 0.32 6.7e-10 Hip circumference; LIHC cis rs1003719 0.788 rs2006941 chr21:38467616 C/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.46e-28 Eye color traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17116739 chr16:67063591 CBFB 0.45 6.06 0.31 3.58e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02396668 chr19:50528878 VRK3;ZNF473 0.48 6.82 0.35 4.23e-11 Pancreatic cancer; LIHC cis rs769267 1.000 rs7247309 chr19:19439631 A/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.44 -6.32 -0.32 8.03e-10 Tonsillectomy; LIHC cis rs1707322 0.717 rs12023439 chr1:46104636 C/T cg03146154 chr1:46216737 IPP 0.55 9.17 0.44 4.38e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs911555 0.755 rs34411783 chr14:103900639 G/A cg17675199 chr6:35436792 RPL10A -0.44 -9.16 -0.44 5.05e-18 Intelligence (multi-trait analysis); LIHC trans rs1656966 1.000 rs1656966 chr3:186466252 C/T cg16465768 chr2:136287945 R3HDM1;ZRANB3 -0.4 -6.04 -0.31 4.02e-9 Myopia (pathological); LIHC cis rs2404602 0.716 rs12594577 chr15:76828793 A/C cg23625390 chr15:77176239 SCAPER 0.37 5.99 0.31 5.18e-9 Blood metabolite levels; LIHC cis rs7927771 1.000 rs11039426 chr11:47863119 G/A cg20307385 chr11:47447363 PSMC3 -0.45 -5.89 -0.3 9.14e-9 Subjective well-being; LIHC cis rs11711311 1.000 rs2566968 chr3:113474154 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.24 -0.36 2.92e-12 IgG glycosylation; LIHC cis rs6748734 1.000 rs11893118 chr2:241828308 C/G cg04034577 chr2:241836375 C2orf54 -0.48 -11.36 -0.52 1.33e-25 Urinary metabolites; LIHC cis rs611744 0.967 rs660816 chr8:109178048 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs3806843 1.000 rs10072015 chr5:140170655 A/T cg19875535 chr5:140030758 IK -0.36 -5.9 -0.3 8.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg06453172 chr10:134556979 INPP5A -0.64 -8.03 -0.4 1.58e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg24549020 chr5:56110836 MAP3K1 -0.5 -6.54 -0.33 2.21e-10 Initial pursuit acceleration; LIHC cis rs10508774 0.850 rs11009020 chr10:32948997 C/G cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9427116 0.531 rs35504625 chr1:154599778 C/G cg17218026 chr1:154582156 ADAR 0.34 6.61 0.34 1.44e-10 Blood protein levels; LIHC trans rs11039798 0.512 rs11040205 chr11:49007360 G/C cg15704280 chr7:45808275 SEPT13 0.6 6.68 0.34 9.57e-11 Axial length; LIHC trans rs8073060 0.586 rs225298 chr17:33923946 T/G cg19694781 chr19:47549865 TMEM160 -1.28 -13.86 -0.6 5.82e-35 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg14983838 chr19:29218262 NA 0.48 7.48 0.38 6.17e-13 Methadone dose in opioid dependence; LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg25897951 chr4:1244024 CTBP1;C4orf42 0.41 5.8 0.3 1.48e-8 Longevity; LIHC trans rs2359714 0.935 rs9661113 chr1:118799439 C/T cg19861078 chr7:7936962 NA 0.31 6.21 0.32 1.52e-9 Breast size; LIHC cis rs7772486 0.790 rs9497427 chr6:146238302 T/A cg05347473 chr6:146136440 FBXO30 -0.35 -5.76 -0.3 1.88e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4141404 0.851 rs5749222 chr22:31556759 C/G cg13145458 chr22:31556086 RNF185 0.45 6.35 0.32 6.8e-10 Paclitaxel-induced neuropathy; LIHC cis rs2153535 0.526 rs9406179 chr6:8538224 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.45 0.42 8.22e-16 Motion sickness; LIHC cis rs16957091 0.909 rs12907826 chr15:43017081 G/A cg24196017 chr15:43021976 CDAN1 -0.4 -5.8 -0.3 1.53e-8 MGMT methylation in smokers; LIHC cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg21016266 chr12:122356598 WDR66 0.43 6.7 0.34 8.35e-11 Mean corpuscular volume; LIHC cis rs1003719 0.715 rs4261789 chr21:38503762 T/G cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.19 -0.52 5.62e-25 Eye color traits; LIHC cis rs10463316 0.894 rs4099168 chr5:150766467 A/G cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.07e-10 Metabolite levels (Pyroglutamine); LIHC cis rs9660992 0.573 rs1172159 chr1:205207512 T/C cg21545522 chr1:205238299 TMCC2 0.38 7.13 0.36 5.94e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs3789045 0.774 rs12029692 chr1:204532323 G/A cg17419461 chr1:204415978 PIK3C2B -0.42 -6.55 -0.33 2.09e-10 Educational attainment (college completion); LIHC cis rs13118159 0.778 rs12650998 chr4:1338832 T/C cg16405210 chr4:1374714 KIAA1530 -0.52 -6.59 -0.34 1.67e-10 Longevity; LIHC cis rs1371867 0.846 rs1788194 chr8:101277916 T/C cg06636551 chr8:101224915 SPAG1 -0.51 -9.54 -0.46 2.72e-19 Atrioventricular conduction; LIHC cis rs722599 0.562 rs2193597 chr14:75234329 G/A cg08847533 chr14:75593920 NEK9 0.5 7.65 0.38 2.13e-13 IgG glycosylation; LIHC cis rs250677 0.652 rs1422582 chr5:148436925 T/C cg12140854 chr5:148520817 ABLIM3 -0.52 -5.81 -0.3 1.4e-8 Breast cancer; LIHC cis rs8067545 0.750 rs7208635 chr17:19990990 T/C cg13482628 chr17:19912719 NA 0.52 8.83 0.43 5.45e-17 Schizophrenia; LIHC cis rs4474742 1 rs4474742 chr17:28065578 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -12.63 -0.56 2.7e-30 Monocyte count; LIHC cis rs986417 0.901 rs9743622 chr14:61037163 A/T cg27398547 chr14:60952738 C14orf39 0.73 8.01 0.4 1.79e-14 Gut microbiota (bacterial taxa); LIHC cis rs11112613 0.713 rs11112591 chr12:105951620 C/T cg03607813 chr12:105948248 NA 0.63 12.34 0.56 3.38e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs6748734 0.857 rs10933638 chr2:241794655 G/A cg20140201 chr2:241835670 C2orf54 -0.5 -7.72 -0.39 1.31e-13 Urinary metabolites; LIHC cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg09904177 chr6:26538194 HMGN4 0.57 11.34 0.52 1.58e-25 Intelligence (multi-trait analysis); LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg00280220 chr17:61926910 NA 0.39 5.91 0.3 8.29e-9 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs2491408 chr1:231519248 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs9768139 0.733 rs12698209 chr7:158117595 A/G cg25566285 chr7:158114605 PTPRN2 -0.22 -6.15 -0.32 2.21e-9 Calcium levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14799008 chr19:42947305 CXCL17 0.51 6.59 0.34 1.7e-10 Systolic blood pressure; LIHC cis rs3806843 1.000 rs3756340 chr5:140180451 T/G cg26395211 chr5:140044315 WDR55 -0.41 -6.13 -0.31 2.41e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10744422 1.000 rs7309225 chr12:123288439 A/G cg07706471 chr12:123319906 HIP1R -0.57 -7.04 -0.36 1.05e-11 Schizophrenia; LIHC cis rs4919694 1.000 rs11191545 chr10:104829793 C/T cg04362960 chr10:104952993 NT5C2 1.07 8.35 0.41 1.77e-15 Arsenic metabolism; LIHC cis rs8017423 0.935 rs7144335 chr14:90732280 A/G cg04374321 chr14:90722782 PSMC1 -0.76 -14.36 -0.61 6.46e-37 Mortality in heart failure; LIHC cis rs11098499 0.644 rs3806808 chr4:120551085 A/C cg09307838 chr4:120376055 NA 0.66 10.16 0.48 2.31e-21 Corneal astigmatism; LIHC cis rs7116495 1.000 rs17161991 chr11:71839960 T/C cg26138937 chr11:71823887 C11orf51 0.83 8.2 0.41 4.93e-15 Severe influenza A (H1N1) infection; LIHC cis rs7520050 0.807 rs6656279 chr1:46124088 C/G cg03146154 chr1:46216737 IPP 0.5 8.54 0.42 4.4e-16 Red blood cell count;Reticulocyte count; LIHC cis rs4407350 1.000 rs12169248 chr22:44920999 G/A cg26276947 chr22:44892394 LDOC1L 0.34 6.32 0.32 8.2e-10 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg06481639 chr22:41940642 POLR3H 0.71 7.16 0.36 4.86e-12 Vitiligo; LIHC cis rs1728785 1.000 rs864742 chr16:68575309 T/C cg02972257 chr16:68554789 NA -0.55 -6.34 -0.32 7.48e-10 Ulcerative colitis; LIHC cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg03264133 chr6:25882463 NA -0.7 -9.15 -0.44 5.15e-18 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.673 rs12103759 chr17:29235687 G/A cg13385521 chr17:29058706 SUZ12P 0.85 8.27 0.41 3.03e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13343954 0.825 rs12461135 chr19:33534185 A/G cg27124370 chr19:33622961 WDR88 0.42 5.73 0.3 2.21e-8 Colorectal cancer; LIHC cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.38e-8 Diabetic kidney disease; LIHC cis rs4665809 0.838 rs6546780 chr2:26352857 T/C cg04944784 chr2:26401820 FAM59B -0.65 -8.27 -0.41 3.05e-15 Gut microbiome composition (summer); LIHC cis rs1355223 0.902 rs1361645 chr11:34746385 G/C cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.43 -0.33 4.18e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs35365539 1 rs35365539 chr3:49794347 A/AC cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Blood protein levels; LIHC cis rs3093024 1.000 rs3093024 chr6:167532793 C/T cg07741184 chr6:167504864 NA 0.26 6.56 0.33 1.93e-10 Rheumatoid arthritis; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg01632497 chr11:8986187 TMEM9B -0.43 -6.44 -0.33 4.04e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7224737 1.000 rs2240009 chr17:40283142 C/G cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs1552244 0.808 rs7615088 chr3:10035896 A/T cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs3862030 0.839 rs12570859 chr10:104257226 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.58 -0.38 3.22e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs3770081 1.000 rs59947468 chr2:86289436 C/T cg01119172 chr2:86362222 SNORD94;PTCD3 0.57 8.8 0.43 7.13e-17 Facial emotion recognition (sad faces); LIHC cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg08392591 chr16:89556376 ANKRD11 0.57 9.15 0.44 5.1e-18 Multiple myeloma (IgH translocation); LIHC trans rs875971 0.502 rs2465121 chr7:65621004 A/G cg26939375 chr7:64535504 NA -0.41 -6.38 -0.33 5.83e-10 Aortic root size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18635645 chr1:85667791 SYDE2 0.51 8.54 0.42 4.4e-16 Cognitive function; LIHC cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg05590025 chr7:65112418 INTS4L2 -0.63 -7.05 -0.36 9.75e-12 Diabetic kidney disease; LIHC trans rs2243480 1.000 rs937108 chr7:65428452 G/A cg10756647 chr7:56101905 PSPH 1.1 13.62 0.59 4.65e-34 Diabetic kidney disease; LIHC cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg12373951 chr3:133503437 NA 0.74 13.81 0.6 8.87e-35 Iron status biomarkers; LIHC cis rs10876993 0.855 rs1689604 chr12:58048304 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.79 -0.34 5.05e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs9858542 0.953 rs35115732 chr3:49475155 T/C cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg06420487 chr17:61919686 SMARCD2 0.43 5.79 0.3 1.62e-8 Height; LIHC cis rs12220238 1.000 rs12220238 chr10:75952670 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.6 0.34 1.61e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs4665809 1.000 rs7588802 chr2:26277789 A/G cg27170947 chr2:26402098 FAM59B -0.66 -8.22 -0.41 4.16e-15 Gut microbiome composition (summer); LIHC cis rs11650494 0.831 rs7216993 chr17:47454263 A/G cg08112188 chr17:47440006 ZNF652 0.81 6.28 0.32 1.03e-9 Prostate cancer; LIHC cis rs7927592 0.913 rs7116994 chr11:68254627 C/T cg20283391 chr11:68216788 NA -0.51 -7.65 -0.38 2.11e-13 Total body bone mineral density; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg07677032 chr17:61819896 STRADA 0.41 5.88 0.3 9.8e-9 Prudent dietary pattern; LIHC cis rs7264396 0.790 rs2207889 chr20:34224898 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -9.91 -0.47 1.59e-20 Total cholesterol levels; LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg00091569 chr3:40428383 ENTPD3 0.39 6.46 0.33 3.51e-10 Renal cell carcinoma; LIHC trans rs5756813 0.754 rs4821708 chr22:38164106 C/T cg19894588 chr14:64061835 NA -0.64 -9.08 -0.44 8.71e-18 Optic cup area;Vertical cup-disc ratio; LIHC cis rs28595532 0.623 rs56324414 chr4:119274655 A/C cg21605333 chr4:119757512 SEC24D 0.84 6.89 0.35 2.75e-11 Cannabis dependence symptom count; LIHC cis rs2842992 0.872 rs1570318 chr6:160111473 C/T cg26839252 chr6:160211577 TCP1;MRPL18 0.36 6.06 0.31 3.58e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs2576037 0.796 rs2576041 chr18:44580919 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.49 -7.43 -0.37 8.6e-13 Personality dimensions; LIHC cis rs644799 1.000 rs564675 chr11:95561873 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs35306767 0.715 rs12777801 chr10:1036285 T/A cg26597838 chr10:835615 NA 0.87 8.14 0.4 7.32e-15 Eosinophil percentage of granulocytes; LIHC cis rs7193541 0.646 rs7188880 chr16:74664810 A/T cg01733217 chr16:74700730 RFWD3 0.92 22.48 0.77 2.3e-69 Multiple myeloma; LIHC cis rs9911578 0.934 rs8081967 chr17:57072701 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.94 0.7 3.47e-51 Intelligence (multi-trait analysis); LIHC cis rs1348850 0.789 rs13027959 chr2:178275887 G/A cg27490568 chr2:178487706 NA 0.36 5.72 0.3 2.35e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs17184557 0.871 rs7239855 chr18:67102963 T/A cg22968167 chr11:4945873 OR51G1 -0.25 -6.13 -0.31 2.48e-9 Osteoporosis-related phenotypes; LIHC cis rs4631830 0.863 rs2843550 chr10:51521452 C/T cg20129853 chr10:51489980 NA -0.43 -9.44 -0.45 6.14e-19 Prostate-specific antigen levels; LIHC cis rs8060686 0.545 rs75229939 chr16:68164949 G/A cg05110241 chr16:68378359 PRMT7 -0.63 -6.99 -0.35 1.45e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg11644478 chr21:40555479 PSMG1 -0.38 -6.14 -0.31 2.33e-9 Menarche (age at onset); LIHC cis rs9916302 0.706 rs8078599 chr17:37518660 C/T cg07936489 chr17:37558343 FBXL20 0.87 12.28 0.55 5.78e-29 Glomerular filtration rate (creatinine); LIHC cis rs909002 0.720 rs4949459 chr1:32142354 G/T cg13919466 chr1:32135498 COL16A1 -0.31 -5.76 -0.3 1.9e-8 Intelligence (multi-trait analysis); LIHC cis rs853679 0.517 rs1340004 chr6:28103691 C/T cg23485639 chr6:28045615 ZNF165 0.44 5.82 0.3 1.32e-8 Depression; LIHC cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg15691649 chr6:25882328 NA -0.53 -7.62 -0.38 2.55e-13 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18502334 chr7:4681577 NA -0.47 -6.31 -0.32 8.82e-10 Pancreatic cancer; LIHC trans rs17685 0.535 rs6953065 chr7:75601169 A/G cg19862616 chr7:65841803 NCRNA00174 -0.5 -7.37 -0.37 1.32e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6754311 0.550 rs10173394 chr2:136522675 C/T cg25344623 chr2:136566232 LCT 0.45 8.95 0.44 2.37e-17 Mosquito bite size; LIHC cis rs4927850 1.000 rs7627868 chr3:195753473 A/T cg12923728 chr3:195709715 SDHAP1 -0.74 -10.61 -0.5 6.46e-23 Pancreatic cancer; LIHC cis rs2404602 0.716 rs56216512 chr15:76686936 T/C cg23625390 chr15:77176239 SCAPER 0.37 6.02 0.31 4.45e-9 Blood metabolite levels; LIHC cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.5 0.33 2.82e-10 Bipolar disorder; LIHC cis rs68170813 0.559 rs2189501 chr7:106942766 A/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs4332037 0.950 rs11771828 chr7:1941003 T/C cg23422044 chr7:1970798 MAD1L1 -0.64 -7.33 -0.37 1.67e-12 Bipolar disorder; LIHC cis rs2286503 0.839 rs2270108 chr7:22862131 A/C cg11367502 chr7:22862612 TOMM7 0.45 7.51 0.38 5.08e-13 Fibrinogen; LIHC cis rs2576037 0.899 rs2060417 chr18:44576486 C/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.1 -0.36 7.14e-12 Personality dimensions; LIHC trans rs7618501 0.699 rs9821675 chr3:49902544 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.61 9.51 0.46 3.63e-19 Intelligence (multi-trait analysis); LIHC cis rs17102423 0.530 rs4902359 chr14:65542790 G/A cg16583315 chr14:65563665 MAX -0.37 -7.57 -0.38 3.55e-13 Obesity-related traits; LIHC cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg23758822 chr17:41437982 NA 0.94 18.0 0.7 1.99e-51 Menopause (age at onset); LIHC cis rs2153535 0.580 rs9393021 chr6:8466123 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs9303401 0.659 rs17822837 chr17:56737838 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.98 0.57 1.31e-31 Cognitive test performance; LIHC cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6540556 0.723 rs9430012 chr1:209900615 G/C cg05527609 chr1:210001259 C1orf107 -0.57 -7.59 -0.38 3.09e-13 Red blood cell count; LIHC cis rs1190552 0.894 rs1190546 chr14:102904966 A/G cg10241871 chr14:102965420 TECPR2 0.47 7.39 0.37 1.14e-12 Blood protein levels; LIHC cis rs708547 0.647 rs1718878 chr4:57876955 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.46 6.75 0.34 6.36e-11 Response to bleomycin (chromatid breaks); LIHC cis rs3015497 0.789 rs1389652 chr14:51125240 T/C cg09863266 chr14:51125203 SAV1 -0.43 -6.8 -0.35 4.66e-11 Mean platelet volume; LIHC cis rs2797160 1.000 rs2211420 chr6:125995549 A/G cg05901451 chr6:126070800 HEY2 -0.41 -7.0 -0.35 1.36e-11 Endometrial cancer; LIHC cis rs2842992 0.830 rs752779 chr6:160133957 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.54 9.59 0.46 1.96e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs950776 0.593 rs588765 chr15:78865425 T/C cg06917634 chr15:78832804 PSMA4 -0.73 -9.83 -0.47 3.04e-20 Sudden cardiac arrest; LIHC cis rs6723226 0.750 rs762019 chr2:32688601 A/C cg02381751 chr2:32503542 YIPF4 0.6 8.96 0.44 2.19e-17 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03710119 chr20:44509748 ZSWIM1 0.43 6.27 0.32 1.07e-9 Pancreatic cancer; LIHC cis rs9297145 0.585 rs13235218 chr7:98785080 C/T cg05967295 chr7:98741636 SMURF1 -0.38 -6.47 -0.33 3.42e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1670533 1.000 rs688785 chr4:1082707 G/C cg27284194 chr4:1044797 NA 0.61 8.98 0.44 1.91e-17 Recombination rate (females); LIHC cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg00612595 chr21:47717864 NA -0.35 -5.84 -0.3 1.24e-8 Testicular germ cell tumor; LIHC cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg06481639 chr22:41940642 POLR3H -0.74 -7.53 -0.38 4.6e-13 Vitiligo; LIHC cis rs9640161 0.750 rs11769348 chr7:150026753 C/T cg10018233 chr7:150070692 REPIN1 -0.52 -8.12 -0.4 8.6e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs7100689 0.646 rs10749581 chr10:82141651 A/G cg01528321 chr10:82214614 TSPAN14 -0.88 -12.58 -0.56 4.3e-30 Post bronchodilator FEV1; LIHC cis rs72627509 1.000 rs72627509 chr4:57839051 C/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.61 -8.73 -0.43 1.11e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1075232 0.522 rs57924788 chr15:31749722 G/A cg01030201 chr15:31746330 NA -0.69 -6.02 -0.31 4.46e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs7903847 0.667 rs7096801 chr10:99140969 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg10360323 chr17:41437877 NA 0.4 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs3981351 0.797 rs12414006 chr10:115461485 A/G cg24846397 chr10:115438155 CASP7 -0.46 -7.13 -0.36 5.86e-12 Obesity-related traits; LIHC cis rs2153535 0.580 rs7769020 chr6:8457724 G/A cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs12701220 0.655 rs34344742 chr7:1149288 C/G cg09177884 chr7:1199841 ZFAND2A -0.51 -5.9 -0.3 8.73e-9 Bronchopulmonary dysplasia; LIHC cis rs4906332 1.000 rs35224956 chr14:103900481 A/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.29 -0.32 9.86e-10 Coronary artery disease; LIHC cis rs9814567 0.793 rs55940445 chr3:134306064 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 11.82 0.54 2.87e-27 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6754311 0.773 rs1435576 chr2:136641882 A/T cg07169764 chr2:136633963 MCM6 0.67 10.02 0.48 7.12e-21 Mosquito bite size; LIHC cis rs35110281 0.713 rs1378079 chr21:45011187 A/G cg01579765 chr21:45077557 HSF2BP -0.34 -6.49 -0.33 2.99e-10 Mean corpuscular volume; LIHC cis rs155076 1.000 rs12870992 chr13:21846019 A/G cg14456004 chr13:21872349 NA 1.11 12.44 0.56 1.47e-29 White matter hyperintensity burden; LIHC cis rs611744 0.967 rs702802 chr8:109218238 G/A cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.74e-17 Dupuytren's disease; LIHC cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg02931644 chr1:25747376 RHCE -0.33 -7.09 -0.36 7.8e-12 Erythrocyte sedimentation rate; LIHC cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.06e-11 Alzheimer's disease; LIHC cis rs1008375 1.000 rs6818639 chr4:17633049 A/G cg04450456 chr4:17643702 FAM184B 0.34 5.73 0.3 2.17e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9790314 0.586 rs73021449 chr3:161128941 G/A cg17135325 chr3:160939158 NMD3 0.49 7.32 0.37 1.73e-12 Morning vs. evening chronotype; LIHC cis rs1113500 1.000 rs1113500 chr1:108595442 G/T cg06207961 chr1:108661230 NA -0.36 -6.85 -0.35 3.44e-11 Growth-regulated protein alpha levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg16993936 chr10:13146903 OPTN 0.39 6.54 0.33 2.19e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs10857712 0.703 rs1056521 chr10:135235890 T/C cg01444801 chr10:135216882 MTG1 -0.63 -9.32 -0.45 1.5e-18 Systemic lupus erythematosus; LIHC cis rs763121 0.853 rs6001185 chr22:39052155 G/A cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs7945718 0.934 rs10831907 chr11:12790875 C/T cg25843174 chr11:12811716 TEAD1 -0.35 -8.13 -0.4 7.99e-15 Educational attainment (years of education); LIHC cis rs2526882 0.562 rs12893492 chr14:71506775 T/C cg15816911 chr14:71606274 NA 0.43 6.92 0.35 2.19e-11 Schizophrenia; LIHC cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg00149659 chr3:10157352 C3orf10 -0.58 -6.33 -0.32 7.55e-10 Alzheimer's disease; LIHC cis rs950169 0.579 rs881983 chr15:84647308 C/T cg17507749 chr15:85114479 UBE2QP1 0.63 5.81 0.3 1.42e-8 Schizophrenia; LIHC cis rs6748734 0.779 rs4401206 chr2:241796905 A/G cg04034577 chr2:241836375 C2orf54 -0.44 -10.09 -0.48 4.03e-21 Urinary metabolites; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg06972615 chr5:77081292 NA 0.35 6.28 0.32 1.04e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2303759 0.709 rs10411679 chr19:49826480 A/T cg22590775 chr19:49891494 CCDC155 0.47 7.47 0.37 6.79e-13 Multiple sclerosis; LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg04267008 chr7:1944627 MAD1L1 -0.64 -10.45 -0.49 2.34e-22 Bipolar disorder and schizophrenia; LIHC cis rs10744422 1.000 rs937766 chr12:123331094 G/T cg25930673 chr12:123319894 HIP1R -0.93 -12.35 -0.56 3.04e-29 Schizophrenia; LIHC cis rs769267 1.000 rs12985655 chr19:19442434 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -9.87 -0.47 2.26e-20 Tonsillectomy; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg11060661 chr22:24314208 DDT;DDTL 0.6 10.12 0.48 3.12e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3960554 1.000 rs2097947 chr7:75836382 A/T cg01364799 chr7:75623366 TMEM120A -0.47 -6.6 -0.34 1.61e-10 Eotaxin levels; LIHC cis rs1789 0.903 rs4453929 chr4:15672173 T/G cg24225360 chr4:15471699 CC2D2A -0.38 -5.91 -0.3 8.24e-9 Blood protein levels; LIHC cis rs881375 0.967 rs1930778 chr9:123641369 A/C cg14580859 chr9:123691850 NA 0.36 6.17 0.32 1.97e-9 Rheumatoid arthritis; LIHC cis rs1577917 0.771 rs4419647 chr6:86225739 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 12.32 0.55 3.97e-29 Response to antipsychotic treatment; LIHC cis rs28830936 0.966 rs17733613 chr15:41917585 A/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.12 -0.31 2.62e-9 Diastolic blood pressure; LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg15773755 chr19:1998801 BTBD2 0.39 6.27 0.32 1.07e-9 Thyroid stimulating hormone; LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg10755058 chr3:40428713 ENTPD3 0.41 7.09 0.36 7.91e-12 Renal cell carcinoma; LIHC cis rs853679 0.598 rs9380054 chr6:28067537 G/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs875971 0.862 rs6952182 chr7:65683317 T/G cg18876405 chr7:65276391 NA -0.35 -6.39 -0.33 5.29e-10 Aortic root size; LIHC cis rs9911578 1.000 rs4793950 chr17:56593111 T/C cg12560992 chr17:57184187 TRIM37 -0.97 -17.64 -0.69 5.52e-50 Intelligence (multi-trait analysis); LIHC cis rs539514 0.718 rs502171 chr13:76320114 T/C cg04757411 chr13:76259545 LMO7 -0.41 -6.9 -0.35 2.56e-11 Type 1 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15695648 chr17:53828850 PCTP 0.44 6.28 0.32 1.03e-9 Cognitive function; LIHC cis rs7091068 0.536 rs503758 chr10:95406935 C/A cg20715218 chr10:95462985 C10orf4 -0.54 -8.33 -0.41 2.02e-15 Urinary tract infection frequency; LIHC cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg25894440 chr7:65020034 NA 0.54 6.25 0.32 1.23e-9 Diabetic kidney disease; LIHC cis rs2070488 0.965 rs6599206 chr3:38545349 C/T cg24069376 chr3:38537580 EXOG -0.43 -7.93 -0.39 3.17e-14 Electrocardiographic conduction measures; LIHC cis rs3008870 1.000 rs2985794 chr1:67425311 T/G cg02640540 chr1:67518911 SLC35D1 0.43 5.93 0.31 7.24e-9 Lymphocyte percentage of white cells; LIHC cis rs11758351 0.866 rs77889957 chr6:26207435 A/G cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs8053891 0.585 rs12926804 chr16:71994932 A/G cg04254540 chr16:71951199 KIAA0174 -0.76 -6.96 -0.35 1.69e-11 Coronary artery disease; LIHC cis rs7249142 0.549 rs741706 chr19:19281672 C/T cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -6.97 -0.35 1.64e-11 IgG glycosylation; LIHC cis rs9649213 0.593 rs34776142 chr7:97899873 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.39 -5.96 -0.31 6.17e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg24209194 chr3:40518798 ZNF619 0.44 6.24 0.32 1.29e-9 Renal cell carcinoma; LIHC cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC trans rs1814175 0.519 rs3913237 chr11:49551828 G/A cg15704280 chr7:45808275 SEPT13 0.79 11.85 0.54 2.32e-27 Height; LIHC cis rs7917772 0.582 rs12779854 chr10:104358474 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.73 -0.39 1.23e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs3768617 0.565 rs10752898 chr1:183077896 A/G ch.1.3577855R chr1:183094577 LAMC1 0.57 9.66 0.46 1.09e-19 Fuchs's corneal dystrophy; LIHC cis rs17604090 0.628 rs875263 chr7:29711066 T/C cg19413766 chr7:29689036 LOC646762 -0.62 -6.35 -0.32 6.78e-10 Facial emotion recognition;Facial emotion recognition (sad faces); LIHC trans rs6461049 0.765 rs1476887 chr7:2151633 T/C cg04565464 chr8:145669602 NFKBIL2 0.38 6.25 0.32 1.24e-9 Schizophrenia; LIHC cis rs17270561 0.609 rs4711094 chr6:25706174 T/A cg17691542 chr6:26056736 HIST1H1C 0.45 5.86 0.3 1.09e-8 Iron status biomarkers; LIHC cis rs7236492 0.532 rs3786184 chr18:77195885 A/C cg15644404 chr18:77186268 NFATC1 -0.37 -5.75 -0.3 2e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2070488 0.804 rs2276541 chr3:38512779 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.59 0.56 4.07e-30 Electrocardiographic conduction measures; LIHC cis rs1018836 0.923 rs7826178 chr8:91649592 C/A cg16814680 chr8:91681699 NA -0.64 -9.83 -0.47 2.91e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1451375 1.000 rs921450 chr7:50623260 A/G cg14593290 chr7:50529359 DDC -0.4 -6.7 -0.34 8.81e-11 Malaria; LIHC cis rs11931598 0.702 rs10937780 chr4:7048842 A/G cg26116260 chr4:7069785 GRPEL1 -0.44 -7.14 -0.36 5.76e-12 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs11190604 0.767 rs4559620 chr10:102199935 C/T cg07080220 chr10:102295463 HIF1AN 0.48 6.83 0.35 4e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7091068 0.754 rs6583903 chr10:95422174 T/C cg20715218 chr10:95462985 C10orf4 0.56 6.25 0.32 1.23e-9 Urinary tract infection frequency; LIHC trans rs3808502 0.527 rs2736374 chr8:11113828 A/G cg09260627 chr8:8243751 NA 0.52 6.35 0.32 6.77e-10 Neuroticism; LIHC cis rs4629710 0.592 rs13205441 chr6:131575069 G/A cg12606694 chr6:131520996 AKAP7 0.65 7.37 0.37 1.26e-12 Multiple myeloma (IgH translocation); LIHC cis rs10792665 0.724 rs1320733 chr11:82719810 C/T cg24227371 chr11:82718527 RAB30 -0.38 -9.3 -0.45 1.69e-18 Obesity-related traits; LIHC cis rs2991971 1.000 rs2934859 chr1:46017836 C/T cg24296786 chr1:45957014 TESK2 0.5 7.21 0.36 3.67e-12 High light scatter reticulocyte count; LIHC cis rs3812111 0.676 rs7758930 chr6:116503168 C/T cg08036074 chr6:116424633 NT5DC1 -0.52 -8.71 -0.43 1.33e-16 Age-related macular degeneration; LIHC cis rs425277 0.539 rs3128337 chr1:2045882 A/G cg04315214 chr1:2043799 PRKCZ 0.46 7.27 0.37 2.52e-12 Height; LIHC cis rs514406 0.792 rs481440 chr1:53344976 C/T cg08859206 chr1:53392774 SCP2 -0.45 -6.57 -0.33 1.88e-10 Monocyte count; LIHC cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg11764359 chr7:65958608 NA 0.69 9.46 0.46 5.3e-19 Aortic root size; LIHC cis rs2115536 0.730 rs4573897 chr15:80187225 G/A cg11839771 chr15:80205821 ST20 -0.28 -5.73 -0.3 2.25e-8 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs600806 0.888 rs4970749 chr1:109873573 G/A cg23091122 chr1:110024289 SYPL2 -0.46 -6.08 -0.31 3.14e-9 Intelligence (multi-trait analysis); LIHC cis rs858239 0.632 rs13438452 chr7:23174182 A/G cg23682824 chr7:23144976 KLHL7 0.45 6.75 0.34 6.33e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs13217239 0.646 rs12209886 chr6:26984757 G/A cg12292205 chr6:26970375 C6orf41 0.45 7.76 0.39 1.02e-13 Schizophrenia; LIHC cis rs6456156 0.586 rs2001115 chr6:167486218 A/C cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.07e-9 Primary biliary cholangitis; LIHC cis rs7572733 0.534 rs11899188 chr2:198740121 C/T cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.74e-11 Dermatomyositis; LIHC cis rs317689 0.513 rs317678 chr12:69692166 C/G cg14784868 chr12:69753453 YEATS4 0.66 10.93 0.51 4.64e-24 Response to diuretic therapy; LIHC cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg14393609 chr7:65229607 NA 0.44 6.51 0.33 2.61e-10 Calcium levels; LIHC trans rs3749237 0.964 rs1799845 chr3:49847623 A/G cg21659725 chr3:3221576 CRBN 0.78 12.05 0.55 4.02e-28 Resting heart rate; LIHC cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs67478160 0.634 rs2024669 chr14:104275602 G/C cg08213375 chr14:104286397 PPP1R13B 0.52 9.64 0.46 1.29e-19 Schizophrenia; LIHC cis rs9937943 0.512 rs13335886 chr16:74577161 C/G cg01733217 chr16:74700730 RFWD3 -0.4 -6.32 -0.32 7.94e-10 Neutrophil percentage of white cells; LIHC cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg08888203 chr3:10149979 C3orf24 0.56 6.39 0.33 5.49e-10 Alzheimer's disease; LIHC cis rs8083850 0.635 rs1367636 chr18:50860752 A/G cg24270629 chr18:50823537 DCC 0.53 8.28 0.41 2.73e-15 Intelligence (multi-trait analysis); LIHC cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg05564831 chr3:52568323 NT5DC2 0.34 5.76 0.3 1.87e-8 Bipolar disorder; LIHC cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg05590025 chr7:65112418 INTS4L2 -0.58 -6.5 -0.33 2.9e-10 Diabetic kidney disease; LIHC cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg11645453 chr3:52864694 ITIH4 0.23 6.17 0.32 1.97e-9 Bipolar disorder; LIHC cis rs10905065 0.735 rs10795347 chr10:5742077 C/G cg11519256 chr10:5708881 ASB13 -0.46 -6.06 -0.31 3.66e-9 Menopause (age at onset); LIHC cis rs10791097 0.694 rs4370948 chr11:130755700 A/C cg12179176 chr11:130786555 SNX19 0.86 14.1 0.61 6.35e-36 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4660306 1.000 rs7534467 chr1:45988691 G/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.67 -0.34 1.02e-10 Homocysteine levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10289325 chr17:37844171 PGAP3;ERBB2 0.41 6.09 0.31 3.09e-9 Cognitive function; LIHC cis rs74233809 1.000 rs12221064 chr10:104677126 C/T cg03493300 chr10:104813866 CNNM2 0.46 6.02 0.31 4.57e-9 Birth weight; LIHC cis rs875971 0.522 rs709604 chr7:65497434 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.31 -5.77 -0.3 1.74e-8 Aortic root size; LIHC cis rs10504073 0.584 rs72641612 chr8:49947986 C/T cg00325661 chr8:49890786 NA 0.35 7.92 0.39 3.28e-14 Blood metabolite ratios; LIHC cis rs10504229 0.593 rs7000752 chr8:58026980 C/G cg02290350 chr8:58132656 NA 0.29 6.57 0.33 1.86e-10 Developmental language disorder (linguistic errors); LIHC cis rs748404 0.631 rs7167882 chr15:43678663 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 8.61 0.42 2.62e-16 Lung cancer; LIHC cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs7520050 0.807 rs3013595 chr1:46153203 G/A cg03146154 chr1:46216737 IPP 0.48 8.07 0.4 1.23e-14 Red blood cell count;Reticulocyte count; LIHC cis rs28374715 0.783 rs11630656 chr15:41570909 T/G cg18705301 chr15:41695430 NDUFAF1 -1.17 -15.5 -0.64 1.99e-41 Ulcerative colitis; LIHC cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.03 -10.57 -0.5 8.95e-23 Platelet count; LIHC cis rs933688 1.000 rs7720132 chr5:90745105 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.39 0.66 5.8e-45 Smoking behavior; LIHC cis rs1003719 0.667 rs73201942 chr21:38475164 G/C cg10648535 chr21:38446584 PIGP;TTC3 0.55 6.42 0.33 4.66e-10 Eye color traits; LIHC cis rs9916302 0.718 rs7219909 chr17:37706243 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.31 -0.58 7.08e-33 Glomerular filtration rate (creatinine); LIHC cis rs7520050 0.966 rs4134386 chr1:46395089 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.6e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4819052 0.679 rs2255761 chr21:46683622 A/G cg22633049 chr21:46681294 NA -0.33 -5.84 -0.3 1.21e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6782228 0.509 rs4481172 chr3:128372657 C/A cg16766828 chr3:128327626 NA -0.4 -6.39 -0.33 5.54e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg27170947 chr2:26402098 FAM59B 0.66 8.23 0.41 3.92e-15 Gut microbiome composition (summer); LIHC cis rs7772486 0.790 rs11760 chr6:146205973 G/T cg13319975 chr6:146136371 FBXO30 -0.35 -5.81 -0.3 1.45e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4638749 0.677 rs13023102 chr2:108837663 C/T cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs2257205 0.667 rs9909763 chr17:56629640 C/T cg05425664 chr17:57184151 TRIM37 -0.58 -6.52 -0.33 2.6e-10 Pancreatic cancer; LIHC cis rs2153535 0.601 rs330105 chr6:8543981 A/C cg21535247 chr6:8435926 SLC35B3 0.64 8.25 0.41 3.43e-15 Motion sickness; LIHC cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg20891558 chr2:74357851 NA 0.8 16.78 0.67 1.53e-46 Gestational age at birth (maternal effect); LIHC cis rs400736 0.930 rs225119 chr1:8044361 T/C cg25007680 chr1:8021821 PARK7 0.61 9.79 0.47 4.13e-20 Response to antidepressants and depression; LIHC cis rs116095464 0.558 rs7356561 chr5:284381 G/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg19635926 chr16:89946313 TCF25 0.54 7.3 0.37 2.02e-12 Skin colour saturation; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg16822855 chr3:40428330 ENTPD3 0.33 5.97 0.31 6.08e-9 Renal cell carcinoma; LIHC cis rs9902453 0.967 rs12450441 chr17:28495021 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.32 0.45 1.47e-18 Coffee consumption (cups per day); LIHC cis rs4700695 0.841 rs784276 chr5:65317332 A/T cg21114390 chr5:65439923 SFRS12 0.49 6.69 0.34 9.15e-11 Facial morphology (factor 19); LIHC cis rs9910055 0.530 rs8072954 chr17:42294722 G/A cg09913183 chr17:42254507 C17orf65;ASB16 0.64 9.4 0.45 7.82e-19 Total body bone mineral density; LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.48 -6.75 -0.34 6.17e-11 Lymphocyte counts; LIHC cis rs6545883 1.000 rs778763 chr2:61785639 C/G cg14146966 chr2:61757674 XPO1 0.46 7.88 0.39 4.49e-14 Tuberculosis; LIHC cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg21433313 chr16:3507492 NAT15 0.47 7.75 0.39 1.09e-13 Tuberculosis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03513109 chr11:126138776 SRPR;FOXRED1 0.47 6.66 0.34 1.12e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3784262 1.000 rs9325 chr15:58245986 A/T cg12031962 chr15:58353849 ALDH1A2 0.32 6.34 0.32 7.13e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg18252515 chr7:66147081 NA -1.24 -16.14 -0.66 5.64e-44 Diabetic kidney disease; LIHC cis rs35306767 0.761 rs34480046 chr10:1027440 A/G cg20503657 chr10:835505 NA 0.84 7.52 0.38 4.8e-13 Eosinophil percentage of granulocytes; LIHC cis rs4755351 0.553 rs10767991 chr11:33169164 T/C cg05567920 chr11:33183001 CSTF3 0.43 6.28 0.32 1.04e-9 Lung cancer in ever smokers; LIHC cis rs5769765 0.913 rs8135071 chr22:50299587 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.19 -0.45 3.85e-18 Schizophrenia; LIHC cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg16434002 chr17:42200994 HDAC5 -0.51 -7.43 -0.37 8.64e-13 Total body bone mineral density; LIHC cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.57 -5.84 -0.3 1.22e-8 Renal cell carcinoma; LIHC cis rs6121246 0.909 rs1075698 chr20:30387992 G/C cg13852791 chr20:30311386 BCL2L1 0.92 9.63 0.46 1.39e-19 Mean corpuscular hemoglobin; LIHC cis rs9733 0.519 rs12095002 chr1:150649249 G/A cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Tonsillectomy; LIHC cis rs2070488 0.775 rs6599204 chr3:38525734 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.64 10.11 0.48 3.3e-21 Electrocardiographic conduction measures; LIHC cis rs12142240 0.698 rs6429599 chr1:46827871 G/A cg00530320 chr1:46809349 NSUN4 0.53 5.74 0.3 2.12e-8 Menopause (age at onset); LIHC cis rs7116495 0.786 rs1573501 chr11:71735693 C/T cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.06e-17 Severe influenza A (H1N1) infection; LIHC cis rs68170813 0.559 rs12533767 chr7:106860245 A/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg08280861 chr8:58055591 NA 0.54 6.21 0.32 1.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs8084351 0.577 rs7226390 chr18:50629407 A/C cg24270629 chr18:50823537 DCC 0.43 6.48 0.33 3.26e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17399234 chr5:110428454 WDR36 0.32 6.46 0.33 3.57e-10 Calcium levels; LIHC cis rs34540877 1.000 rs11667412 chr19:33137748 T/C cg22980127 chr19:33182716 NUDT19 1.0 6.63 0.34 1.33e-10 Red cell distribution width; LIHC cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg27572855 chr1:25598939 RHD 0.43 9.55 0.46 2.5e-19 Plateletcrit;Mean corpuscular volume; LIHC cis rs6582630 0.519 rs4294627 chr12:38293982 C/T cg26384229 chr12:38710491 ALG10B 0.59 8.13 0.4 7.75e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg21433313 chr16:3507492 NAT15 -0.45 -8.25 -0.41 3.5e-15 Tuberculosis; LIHC trans rs4824093 0.610 rs3761496 chr22:50246466 T/C cg09872104 chr7:134855509 C7orf49 -0.78 -6.29 -0.32 9.54e-10 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs4268898 0.965 rs13033241 chr2:24476118 G/C cg06627628 chr2:24431161 ITSN2 0.52 7.4 0.37 1.05e-12 Asthma; LIHC trans rs79243044 0.786 rs16932549 chr11:5560909 C/T cg26026558 chr17:16934655 NA -0.38 -6.24 -0.32 1.33e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg20607798 chr8:58055168 NA 0.6 8.84 0.43 5.14e-17 Developmental language disorder (linguistic errors); LIHC cis rs17253792 0.822 rs11546 chr14:56146357 G/A cg01858014 chr14:56050164 KTN1 -0.7 -8.08 -0.4 1.12e-14 Putamen volume; LIHC cis rs2153535 0.580 rs4960412 chr6:8438261 G/C cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.3e-16 Motion sickness; LIHC cis rs3812831 0.695 rs423237 chr13:114930955 C/T cg08824895 chr13:115047677 UPF3A 0.48 6.9 0.35 2.58e-11 Schizophrenia; LIHC cis rs2549003 0.811 rs10072700 chr5:131816903 A/C cg21138405 chr5:131827807 IRF1 0.37 7.05 0.36 9.79e-12 Asthma (sex interaction); LIHC cis rs2204008 0.744 rs11519905 chr12:38222959 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.72 0.5 2.64e-23 Bladder cancer; LIHC cis rs4819052 0.807 rs4819047 chr21:46665139 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.48 0.37 6.37e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs61990749 0.597 rs7147516 chr14:78153980 T/C cg21497246 chr14:78225524 SNW1;C14orf178 0.5 7.7 0.38 1.48e-13 Fibroblast growth factor basic levels; LIHC cis rs2153535 0.580 rs2143357 chr6:8497196 A/G cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.23e-27 Motion sickness; LIHC cis rs3818285 0.515 rs4918471 chr10:111660500 C/A cg00817464 chr10:111662876 XPNPEP1 -0.53 -8.35 -0.41 1.69e-15 Superior crus of antihelix expression; LIHC trans rs1814175 0.647 rs10769646 chr11:49992204 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs3806843 0.900 rs2563279 chr5:140131535 G/A cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.97 9.12 0.44 6.71e-18 Platelet count; LIHC trans rs17685 0.753 rs1859791 chr7:75786043 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg25894440 chr7:65020034 NA -0.53 -6.04 -0.31 4.05e-9 Diabetic kidney disease; LIHC cis rs703842 1.000 rs4646536 chr12:58157988 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.83 13.73 0.6 1.8e-34 Multiple sclerosis; LIHC cis rs11690935 0.959 rs10194102 chr2:172626143 G/C cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.71 -0.69 2.95e-50 Schizophrenia; LIHC cis rs34375054 0.624 rs12832525 chr12:125680366 T/C cg25124228 chr12:125621409 AACS -0.44 -7.38 -0.37 1.19e-12 Post bronchodilator FEV1/FVC ratio; LIHC cis rs72627123 0.867 rs73301475 chr14:74462868 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 8.77 0.43 8.53e-17 Morning vs. evening chronotype; LIHC cis rs6545883 0.965 rs12713439 chr2:61752154 G/A cg15711740 chr2:61764176 XPO1 -0.44 -6.19 -0.32 1.73e-9 Tuberculosis; LIHC cis rs1005277 0.579 rs2474574 chr10:38387295 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs4665809 1.000 rs750450 chr2:26324631 A/G cg27170947 chr2:26402098 FAM59B -0.65 -8.1 -0.4 9.74e-15 Gut microbiome composition (summer); LIHC trans rs11088226 0.681 rs2833903 chr21:33940819 C/T cg09050820 chr6:167586206 TCP10L2 0.87 13.33 0.58 6.06e-33 Gastritis; LIHC cis rs6430585 0.583 rs78364332 chr2:136640101 T/C cg07169764 chr2:136633963 MCM6 1.35 24.5 0.8 2.82e-77 Corneal structure; LIHC cis rs9811920 0.638 rs793440 chr3:99643176 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.81 0.3 1.43e-8 Axial length; LIHC cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.37e-12 Bipolar disorder; LIHC cis rs11711311 1.000 rs2566963 chr3:113531849 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 0.39 7.02 0.35 1.2e-11 IgG glycosylation; LIHC cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg02503808 chr4:7069936 GRPEL1 0.8 12.02 0.54 5.47e-28 Monocyte percentage of white cells; LIHC cis rs1198430 0.639 rs2297841 chr1:23764149 C/G cg19827787 chr1:23763612 ASAP3 0.29 6.22 0.32 1.48e-9 Total cholesterol levels; LIHC cis rs11148252 0.875 rs7987115 chr13:52962097 C/T cg00495681 chr13:53174319 NA 0.38 6.18 0.32 1.79e-9 Lewy body disease; LIHC cis rs11718455 0.767 rs6785433 chr3:43964265 A/G cg08738300 chr3:44038990 NA 0.52 8.86 0.43 4.35e-17 Coronary artery disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18649979 chr19:21688263 ZNF429 -0.44 -6.26 -0.32 1.13e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs7613875 0.600 rs2856238 chr3:50158191 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.44 6.62 0.34 1.39e-10 Body mass index; LIHC cis rs17685 0.725 rs7795291 chr7:75725206 C/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.37 -6.13 -0.31 2.46e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17685 0.672 rs1639618 chr7:75701987 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg11644478 chr21:40555479 PSMG1 -0.39 -6.03 -0.31 4.36e-9 Cognitive function; LIHC trans rs1814175 0.645 rs4411280 chr11:49962750 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs4671400 0.516 rs62152277 chr2:61503404 C/T cg14146966 chr2:61757674 XPO1 -0.37 -5.86 -0.3 1.1e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs9300255 0.596 rs10773002 chr12:123746961 A/T cg00376283 chr12:123451042 ABCB9 -0.65 -10.06 -0.48 4.94e-21 Neutrophil percentage of white cells; LIHC cis rs12291225 0.585 rs10832242 chr11:14340504 C/T cg05501817 chr11:14380813 RRAS2 0.44 6.23 0.32 1.35e-9 Sense of smell; LIHC cis rs4919694 1.000 rs4917379 chr10:104752831 A/T cg04362960 chr10:104952993 NT5C2 1.06 8.05 0.4 1.39e-14 Arsenic metabolism; LIHC cis rs7659604 0.539 rs7686084 chr4:122764725 A/C cg19748678 chr4:122722346 EXOSC9 0.67 11.17 0.52 6.53e-25 Type 2 diabetes; LIHC cis rs3820068 0.581 rs74054797 chr1:15926217 G/A cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs2075371 0.863 rs12707139 chr7:133954153 A/G cg11752832 chr7:134001865 SLC35B4 0.48 6.02 0.31 4.62e-9 Mean platelet volume; LIHC cis rs10504229 0.593 rs4738567 chr8:57997033 A/C cg20607798 chr8:58055168 NA 0.48 6.66 0.34 1.08e-10 Developmental language disorder (linguistic errors); LIHC cis rs9921222 0.500 rs12917907 chr16:405866 C/T cg26944245 chr16:421049 TMEM8A;MRPL28 0.45 7.77 0.39 9.53e-14 Bone mineral density (spine);Bone mineral density; LIHC trans rs11098499 1.000 rs11726229 chr4:120211580 C/T cg25214090 chr10:38739885 LOC399744 0.51 7.76 0.39 9.62e-14 Corneal astigmatism; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg19963142 chr11:58345608 ZFP91;LPXN;ZFP91-CNTF -0.43 -6.14 -0.32 2.34e-9 Neuroblastoma; LIHC cis rs7659604 0.518 rs17452156 chr4:122733623 T/C cg20573242 chr4:122745356 CCNA2 0.53 7.69 0.38 1.58e-13 Type 2 diabetes; LIHC cis rs4665809 1.000 rs6709595 chr2:26259885 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.45 -0.42 8.76e-16 Gut microbiome composition (summer); LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.52 -0.38 4.89e-13 Lymphocyte counts; LIHC cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg24101359 chr6:42928495 GNMT 0.43 5.84 0.3 1.23e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2153535 0.601 rs9393030 chr6:8516489 C/G cg21535247 chr6:8435926 SLC35B3 0.63 8.29 0.41 2.64e-15 Motion sickness; LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg12379764 chr21:47803548 PCNT -0.61 -8.85 -0.43 4.96e-17 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg12463550 chr7:65579703 CRCP 0.69 7.22 0.36 3.46e-12 Diabetic kidney disease; LIHC cis rs8078723 0.738 rs4065321 chr17:38143548 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.29 0.52 2.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9393692 0.902 rs6456711 chr6:26302572 A/C cg13736514 chr6:26305472 NA -0.42 -6.56 -0.33 2.01e-10 Educational attainment; LIHC trans rs1814175 0.647 rs1404157 chr11:49917301 G/C cg18944383 chr4:111397179 ENPEP 0.24 6.09 0.31 3.01e-9 Height; LIHC cis rs15676 0.947 rs2293966 chr9:131591832 G/A cg00228799 chr9:131580591 ENDOG 0.44 6.6 0.34 1.56e-10 Blood metabolite levels; LIHC cis rs1198430 1.000 rs1198439 chr1:23749593 A/T cg13183780 chr1:23809682 ASAP3 -0.48 -7.22 -0.36 3.3e-12 Total cholesterol levels; LIHC cis rs13631 0.894 rs7856589 chr9:140003921 A/G cg14289826 chr9:140003911 NA -0.52 -9.32 -0.45 1.45e-18 Cerebrospinal fluid biomarker levels; LIHC cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg18230493 chr5:56204884 C5orf35 -0.45 -6.3 -0.32 9.04e-10 Initial pursuit acceleration; LIHC cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg25894440 chr7:65020034 NA -0.53 -6.11 -0.31 2.72e-9 Diabetic kidney disease; LIHC cis rs7264396 0.563 rs2425131 chr20:34337074 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.75 -0.43 1.02e-16 Total cholesterol levels; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg10016717 chr17:88246 RPH3AL 0.61 6.6 0.34 1.54e-10 Mean platelet volume; LIHC cis rs921968 0.678 rs689116 chr2:219433888 C/A cg18887096 chr2:219472410 PLCD4 0.36 6.29 0.32 9.97e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14266050 chr4:2845671 ADD1 -0.44 -6.09 -0.31 2.97e-9 Bilirubin levels; LIHC trans rs9747201 0.926 rs35131420 chr17:80103631 T/C cg07393940 chr7:158741817 NA -0.57 -6.95 -0.35 1.85e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg06481639 chr22:41940642 POLR3H 0.71 7.06 0.36 9.26e-12 Vitiligo; LIHC cis rs2066819 1.000 rs41363748 chr12:56696056 C/T cg26714650 chr12:56694279 CS 1.38 13.72 0.6 2e-34 Psoriasis vulgaris; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg24693881 chr1:107596107 NA -0.54 -9.46 -0.46 4.95e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg27297192 chr10:134578999 INPP5A 0.55 8.1 0.4 9.95e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs7551222 0.752 rs12566957 chr1:204556958 C/T cg20240347 chr1:204465584 NA -0.31 -6.34 -0.32 7.1e-10 Schizophrenia; LIHC cis rs317689 0.819 rs317664 chr12:69704747 C/A cg19645103 chr12:69753606 YEATS4 -0.45 -6.19 -0.32 1.72e-9 Response to diuretic therapy; LIHC cis rs8060686 0.546 rs7188350 chr16:68149316 T/C cg05110241 chr16:68378359 PRMT7 -0.5 -6.0 -0.31 5.05e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs7666738 0.539 rs13150465 chr4:99094892 C/T cg05340658 chr4:99064831 C4orf37 -0.68 -7.58 -0.38 3.24e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs244293 0.965 rs244314 chr17:53214517 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.37 -0.37 1.27e-12 Menarche (age at onset); LIHC cis rs8005677 0.962 rs8003934 chr14:23401142 A/G cg25600027 chr14:23388339 RBM23 -0.41 -5.99 -0.31 5.17e-9 Cognitive ability (multi-trait analysis); LIHC cis rs6502050 0.835 rs4789754 chr17:80091941 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -6.01 -0.31 4.76e-9 Life satisfaction; LIHC cis rs2404602 0.530 rs11072614 chr15:76967205 G/A cg03037974 chr15:76606532 NA -0.51 -8.27 -0.41 3.1e-15 Blood metabolite levels; LIHC cis rs17685 0.697 rs2302437 chr7:75677016 G/A cg04592579 chr7:75616294 TMEM120A -0.39 -6.68 -0.34 9.92e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11577318 0.853 rs2276712 chr1:26627478 T/C cg18121669 chr1:26560928 CCDC21 0.5 8.0 0.4 1.91e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs3770081 1.000 rs3770089 chr2:86263815 C/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.85 -8.75 -0.43 1e-16 Facial emotion recognition (sad faces); LIHC cis rs6442522 0.560 rs2305612 chr3:15518731 C/G cg16303742 chr3:15540471 COLQ 0.37 5.91 0.3 8.45e-9 Uric acid levels; LIHC cis rs9388451 0.531 rs9375414 chr6:126154475 G/A cg05901451 chr6:126070800 HEY2 -0.44 -7.52 -0.38 4.81e-13 Brugada syndrome; LIHC cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg13047869 chr3:10149882 C3orf24 0.52 6.28 0.32 1.05e-9 Alzheimer's disease; LIHC cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.37 0.45 9.93e-19 Bipolar disorder; LIHC cis rs9916302 0.904 rs2024073 chr17:37471330 T/G cg07936489 chr17:37558343 FBXL20 0.84 13.68 0.59 2.79e-34 Glomerular filtration rate (creatinine); LIHC cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg15691649 chr6:25882328 NA -0.54 -7.75 -0.39 1.07e-13 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10795710 chr1:16693622 C1orf144 0.43 6.74 0.34 6.74e-11 Pancreatic cancer; LIHC cis rs74181299 0.964 rs2540951 chr2:65276736 A/G cg05010058 chr2:65284262 CEP68 0.4 6.7 0.34 8.6e-11 Pulse pressure; LIHC cis rs79839061 0.520 rs6842808 chr4:906903 C/T cg07828340 chr4:882639 GAK 0.81 6.69 0.34 8.93e-11 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg26119090 chr2:26468346 HADHA;HADHB -1.11 -15.49 -0.64 2.29e-41 Gut microbiome composition (summer); LIHC cis rs6466055 0.748 rs41563 chr7:104852654 G/A cg04380332 chr7:105027541 SRPK2 -0.34 -6.4 -0.33 5.25e-10 Schizophrenia; LIHC cis rs2386661 0.547 rs72781996 chr10:5646485 C/G cg17085576 chr10:5658249 NA -0.34 -6.05 -0.31 3.9e-9 Breast cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11412256 chr1:228612818 HIST3H3 -0.37 -6.12 -0.31 2.63e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2243480 1.000 rs2177703 chr7:65391717 C/A cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg00280220 chr17:61926910 NA 0.42 6.64 0.34 1.23e-10 Prudent dietary pattern; LIHC cis rs854765 0.647 rs8066764 chr17:17974668 C/T cg04398451 chr17:18023971 MYO15A -0.63 -10.46 -0.49 2.04e-22 Total body bone mineral density; LIHC cis rs7412746 0.658 rs72704682 chr1:150897677 A/T cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs1816752 0.774 rs55888616 chr13:25016092 C/T cg02811702 chr13:24901961 NA 0.26 6.63 0.34 1.3100000000000001e-10 Obesity-related traits; LIHC cis rs7223966 0.960 rs11659013 chr17:61869559 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.76 0.34 5.99e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7582720 1.000 rs72932572 chr2:203859391 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.1 0.31 2.88e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg19635926 chr16:89946313 TCF25 0.52 7.02 0.36 1.17e-11 Skin colour saturation; LIHC cis rs9394841 0.692 rs2395795 chr6:41802354 G/A cg08135965 chr6:41755394 TOMM6 0.46 6.13 0.31 2.41e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg07636037 chr3:49044803 WDR6 0.89 15.54 0.64 1.43e-41 Parkinson's disease; LIHC cis rs6912958 0.559 rs107689 chr6:88069333 G/T cg12350822 chr6:88032061 C6orf162;GJB7 0.38 7.49 0.38 5.75e-13 Monocyte percentage of white cells; LIHC cis rs7027203 0.964 rs7853688 chr9:96523254 C/A cg14598338 chr9:96623480 NA 0.31 5.97 0.31 5.98e-9 DNA methylation (variation); LIHC trans rs2727020 0.731 rs10450572 chr11:49281073 T/C cg03929089 chr4:120376271 NA 0.81 14.27 0.61 1.37e-36 Coronary artery disease; LIHC cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg27572855 chr1:25598939 RHD 0.4 8.67 0.42 1.74e-16 Erythrocyte sedimentation rate; LIHC trans rs2243480 0.803 rs403089 chr7:65517723 T/C cg10756647 chr7:56101905 PSPH 1.08 13.33 0.58 6.29e-33 Diabetic kidney disease; LIHC cis rs16828019 0.929 rs35286837 chr1:41682998 T/G cg20697417 chr1:41786797 NA 0.34 6.51 0.33 2.61e-10 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 21.61 0.76 6.3e-66 Prudent dietary pattern; LIHC cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg21644426 chr2:191273491 MFSD6 -0.53 -7.43 -0.37 8.62e-13 Pulse pressure; LIHC cis rs11148252 0.553 rs9536236 chr13:53255012 T/A cg00495681 chr13:53174319 NA 0.7 12.84 0.57 4.54e-31 Lewy body disease; LIHC cis rs4407350 0.870 rs5765715 chr22:44915217 A/G cg11695653 chr22:44894386 LDOC1L -0.36 -6.2 -0.32 1.6e-9 Intelligence (multi-trait analysis); LIHC cis rs143283559 1 rs143283559 chr18:77567761 T/G cg13263691 chr18:77568018 NA 0.25 6.82 0.35 4.08e-11 Intelligence (multi-trait analysis); LIHC cis rs7618501 0.519 rs3774749 chr3:50207227 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.49 -6.58 -0.34 1.8e-10 Intelligence (multi-trait analysis); LIHC cis rs332507 0.601 rs11711670 chr3:124374215 G/A cg05980111 chr3:124395277 KALRN 0.32 6.21 0.32 1.57e-9 Plateletcrit; LIHC cis rs2302190 0.882 rs8068135 chr17:56654210 A/C cg12560992 chr17:57184187 TRIM37 0.68 8.74 0.43 1.03e-16 Vitamin D levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02048674 chr19:49991517 RPL13AP5;RPL13A 0.42 6.17 0.32 1.91e-9 Cognitive function; LIHC cis rs7086627 0.515 rs10887896 chr10:82210144 A/C cg00277334 chr10:82204260 NA -0.85 -13.76 -0.6 1.3600000000000001e-34 Post bronchodilator FEV1; LIHC cis rs919433 0.647 rs13404366 chr2:198522632 A/G cg00792783 chr2:198669748 PLCL1 0.4 5.98 0.31 5.46e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs240768 0.511 rs61289570 chr6:101403098 C/T cg12253828 chr6:101329408 ASCC3 0.97 12.09 0.55 3.03e-28 Economic and political preferences (immigration/crime); LIHC cis rs7296418 0.630 rs28419092 chr12:123812629 G/C cg05973401 chr12:123451056 ABCB9 0.41 6.3 0.32 8.98e-10 Platelet count; LIHC cis rs589448 0.538 rs622656 chr12:69753595 C/T cg14784868 chr12:69753453 YEATS4 0.86 16.28 0.66 1.52e-44 Cerebrospinal fluid biomarker levels; LIHC cis rs8038465 0.592 rs899981 chr15:73935329 G/A cg15420318 chr15:73925796 NPTN 0.49 7.41 0.37 1.01e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg10820262 chr4:111866929 NA 0.39 6.47 0.33 3.44e-10 Electroencephalogram traits; LIHC cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg18404041 chr3:52824283 ITIH1 -0.58 -9.33 -0.45 1.42e-18 Bipolar disorder; LIHC cis rs7937890 0.684 rs12799007 chr11:14426484 T/A cg02886208 chr11:14281011 SPON1 -0.54 -7.61 -0.38 2.75e-13 Mitochondrial DNA levels; LIHC cis rs9596863 0.898 rs7993276 chr13:54323868 A/G ch.13.53330881F chr13:54432880 NA 0.43 5.92 0.3 8.01e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1144333 0.850 rs1144341 chr1:76282659 T/G cg10523679 chr1:76189770 ACADM -0.46 -6.63 -0.34 1.29e-10 Attention function in attention deficit hyperactive disorder; LIHC trans rs7618501 0.521 rs3796386 chr3:49899795 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.58 0.34 1.74e-10 Intelligence (multi-trait analysis); LIHC cis rs4555082 0.915 rs28594491 chr14:105758018 G/A cg06808227 chr14:105710500 BRF1 -0.5 -6.46 -0.33 3.62e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs7552404 0.731 rs5745458 chr1:76345429 G/A cg03433033 chr1:76189801 ACADM -0.55 -6.51 -0.33 2.67e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs864643 0.947 rs587054 chr3:39565987 A/G cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC trans rs877282 0.583 rs11253428 chr10:823233 C/T cg22713356 chr15:30763199 NA 0.79 6.78 0.34 5.39e-11 Uric acid levels; LIHC cis rs35110281 0.805 rs3788062 chr21:44991159 C/T cg21573476 chr21:45109991 RRP1B -0.54 -10.25 -0.48 1.1e-21 Mean corpuscular volume; LIHC cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg03806693 chr22:41940476 POLR3H -1.1 -13.13 -0.58 3.71e-32 Vitiligo; LIHC trans rs11098499 0.954 rs10006706 chr4:120409152 A/G cg25214090 chr10:38739885 LOC399744 0.58 9.35 0.45 1.17e-18 Corneal astigmatism; LIHC cis rs7917772 0.503 rs746552 chr10:104342501 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.75 0.57 9.72e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17376456 0.877 rs10476596 chr5:93367074 C/T cg25358565 chr5:93447407 FAM172A -1.1 -10.02 -0.48 6.9299999999999992e-21 Diabetic retinopathy; LIHC cis rs6062302 0.548 rs6089940 chr20:62252695 C/T cg16989086 chr20:62203971 PRIC285 0.56 8.2 0.41 4.9e-15 Glioblastoma; LIHC cis rs6430585 0.528 rs114760827 chr2:136661110 G/A cg25344623 chr2:136566232 LCT -0.38 -6.1 -0.31 2.88e-9 Corneal structure; LIHC cis rs7727544 0.684 rs274546 chr5:131699867 A/G cg24060327 chr5:131705240 SLC22A5 -0.58 -8.45 -0.42 8.39e-16 Blood metabolite levels; LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.545 rs316306 chr7:65618674 G/A cg11764359 chr7:65958608 NA -0.51 -7.08 -0.36 8.1e-12 Aortic root size; LIHC cis rs12594515 1.000 rs11855562 chr15:45995659 C/T cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs9911578 0.765 rs66954617 chr17:56999427 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26304930 chr1:119571871 NA 0.35 6.11 0.31 2.78e-9 Cognitive function; LIHC cis rs7914558 0.933 rs1538204 chr10:104733893 T/A cg15744005 chr10:104629667 AS3MT -0.41 -9.34 -0.45 1.23e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg02034447 chr16:89574710 SPG7 0.5 7.78 0.39 8.68e-14 Multiple myeloma (IgH translocation); LIHC cis rs2731664 0.756 rs4976695 chr5:176862963 T/A cg23176889 chr5:176863531 GRK6 -0.7 -12.37 -0.56 2.64e-29 Intelligence (multi-trait analysis); LIHC cis rs17376456 0.877 rs13169675 chr5:93331284 A/G cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.53e-21 Diabetic retinopathy; LIHC cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs2645424 0.666 rs2272767 chr8:11711059 C/T cg21281001 chr8:11725306 CTSB 0.53 8.26 0.41 3.14e-15 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); LIHC cis rs2354432 0.607 rs1530336 chr1:146685121 G/A cg25205988 chr1:146714368 CHD1L 0.98 6.47 0.33 3.34e-10 Mitochondrial DNA levels; LIHC cis rs644799 1.000 rs651445 chr11:95539122 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1707322 1.000 rs10890372 chr1:46391020 T/G cg06784218 chr1:46089804 CCDC17 0.34 6.03 0.31 4.19e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.58 9.76 0.47 5.17e-20 Prudent dietary pattern; LIHC cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg06238570 chr21:40685208 BRWD1 -0.54 -9.05 -0.44 1.12e-17 Cognitive function; LIHC cis rs360798 0.532 rs360800 chr2:62954326 C/T cg17519650 chr2:63277830 OTX1 -0.58 -8.79 -0.43 7.5e-17 Coronary artery disease; LIHC cis rs13108904 0.901 rs13112706 chr4:1303682 G/T cg05665937 chr4:1216051 CTBP1 0.44 5.77 0.3 1.77e-8 Obesity-related traits; LIHC cis rs7584330 0.554 rs4420668 chr2:238444793 G/A cg08992911 chr2:238395768 MLPH 0.5 6.01 0.31 4.86e-9 Prostate cancer; LIHC cis rs79149102 0.579 rs79916508 chr15:75373721 A/C cg15902774 chr15:75289873 SCAMP5 0.4 5.95 0.31 6.63e-9 Lung cancer; LIHC cis rs9527 0.637 rs12219247 chr10:104613361 A/G cg15744005 chr10:104629667 AS3MT -0.43 -9.76 -0.47 5.25e-20 Arsenic metabolism; LIHC cis rs17253792 0.822 rs28481586 chr14:56053863 C/G cg01858014 chr14:56050164 KTN1 -0.74 -8.25 -0.41 3.55e-15 Putamen volume; LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg14893161 chr1:205819251 PM20D1 0.8 11.83 0.54 2.6e-27 Menarche (age at onset); LIHC cis rs3812111 0.774 rs568725 chr6:116430803 G/A cg08036074 chr6:116424633 NT5DC1 0.67 12.09 0.55 2.93e-28 Age-related macular degeneration; LIHC cis rs7927592 0.913 rs59056571 chr11:68272973 T/G cg16797656 chr11:68205561 LRP5 0.53 8.31 0.41 2.22e-15 Total body bone mineral density; LIHC cis rs9473924 0.542 rs2857506 chr6:50800308 C/T cg14470998 chr6:50812995 TFAP2B 0.97 11.7 0.53 8.07e-27 Body mass index; LIHC cis rs763121 0.853 rs1043441 chr22:39130964 C/T cg06544989 chr22:39130855 UNC84B 0.37 5.88 0.3 9.77e-9 Menopause (age at onset); LIHC cis rs7582720 1.000 rs72934510 chr2:203925360 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1003719 0.680 rs2154537 chr21:38502012 G/C cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.17 -0.52 6.62e-25 Eye color traits; LIHC cis rs796364 0.789 rs176008 chr2:200814720 A/T cg23649088 chr2:200775458 C2orf69 0.51 6.32 0.32 8.22e-10 Schizophrenia; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg15382696 chr6:118971807 C6orf204 0.63 6.37 0.33 6.05e-10 Diastolic blood pressure; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg12664560 chr15:83621517 HOMER2 0.52 6.2 0.32 1.65e-9 Hepatitis; LIHC cis rs1816752 0.837 rs4769355 chr13:25015197 G/A cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs9814567 1.000 rs9826496 chr3:134224437 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.39 -5.82 -0.3 1.37e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1975974 0.549 rs4889746 chr17:21745187 T/C cg18423549 chr17:21743878 NA -0.47 -5.81 -0.3 1.47e-8 Psoriasis; LIHC cis rs67311347 0.955 rs60554147 chr3:40472503 T/C cg00656387 chr3:40428638 ENTPD3 0.42 7.02 0.35 1.21e-11 Renal cell carcinoma; LIHC cis rs7618501 0.902 rs7645061 chr3:49868842 C/T cg21467203 chr3:49911342 NA -0.4 -6.98 -0.35 1.56e-11 Intelligence (multi-trait analysis); LIHC cis rs9486719 0.843 rs2499796 chr6:96848364 A/G cg06623918 chr6:96969491 KIAA0776 0.7 6.88 0.35 2.79e-11 Migraine;Coronary artery disease; LIHC cis rs5753037 0.774 rs140118 chr22:30135806 G/A cg01021169 chr22:30184971 ASCC2 -0.31 -5.79 -0.3 1.56e-8 Type 1 diabetes; LIHC cis rs7937682 0.924 rs10891288 chr11:111552053 G/T cg09085632 chr11:111637200 PPP2R1B 1.07 14.18 0.61 3.17e-36 Primary sclerosing cholangitis; LIHC trans rs7395662 0.571 rs10838947 chr11:48568693 G/T cg15704280 chr7:45808275 SEPT13 -0.46 -6.89 -0.35 2.62e-11 HDL cholesterol; LIHC cis rs4268898 0.662 rs2891382 chr2:24511491 C/G cg06627628 chr2:24431161 ITSN2 -0.73 -9.88 -0.47 2.06e-20 Asthma; LIHC cis rs9816226 0.591 rs75135487 chr3:185805294 C/G cg00760338 chr3:185826511 ETV5 -0.71 -5.99 -0.31 5.27e-9 Obesity;Body mass index; LIHC cis rs1577917 0.958 rs12213331 chr6:86504797 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.36 -0.49 4.77e-22 Response to antipsychotic treatment; LIHC cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg06212747 chr3:49208901 KLHDC8B 0.65 9.02 0.44 1.37e-17 Menarche (age at onset); LIHC cis rs9303401 0.659 rs1864754 chr17:56688789 G/T cg25039879 chr17:56429692 SUPT4H1 -0.77 -8.68 -0.42 1.66e-16 Cognitive test performance; LIHC cis rs7000551 0.725 rs2248987 chr8:22399002 C/G cg13512537 chr8:22265999 SLC39A14 -0.33 -5.88 -0.3 9.61e-9 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs826838 1.000 rs11168367 chr12:38913397 T/G cg13010199 chr12:38710504 ALG10B 0.6 7.29 0.37 2.21e-12 Heart rate; LIHC cis rs1046896 0.514 rs67735447 chr17:80823042 G/T cg22027946 chr17:80790580 TBCD;ZNF750 0.51 7.5 0.38 5.66e-13 Glycated hemoglobin levels; LIHC cis rs2073300 1.000 rs6048824 chr20:23457645 C/A cg12062639 chr20:23401060 NAPB 0.78 9.7 0.46 8.37e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6582630 0.555 rs2004152 chr12:38478951 C/T cg13010199 chr12:38710504 ALG10B 0.57 6.7 0.34 8.4e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs3849570 0.555 rs6548783 chr3:81993621 G/A cg07356753 chr3:81810745 GBE1 -0.42 -6.57 -0.33 1.91e-10 Waist circumference;Body mass index; LIHC cis rs1577917 0.958 rs11754330 chr6:86455070 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.45 -0.37 7.86e-13 Response to antipsychotic treatment; LIHC trans rs4332037 0.539 rs34809719 chr7:2028968 G/T cg11693508 chr17:37793320 STARD3 0.66 6.61 0.34 1.5e-10 Bipolar disorder; LIHC cis rs8180040 0.764 rs13084117 chr3:47183239 C/A cg27129171 chr3:47204927 SETD2 0.69 12.1 0.55 2.64e-28 Colorectal cancer; LIHC cis rs12594515 1.000 rs6493172 chr15:45987213 T/G cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.69e-10 Waist circumference;Weight; LIHC cis rs7246657 0.943 rs4969487 chr19:37831039 C/T cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC cis rs2243480 1.000 rs73142122 chr7:65311298 C/A cg12463550 chr7:65579703 CRCP 0.7 7.15 0.36 5.32e-12 Diabetic kidney disease; LIHC cis rs7772486 0.790 rs2247666 chr6:146220409 C/A cg23711669 chr6:146136114 FBXO30 0.71 12.36 0.56 2.98e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs10870270 0.830 rs11146269 chr10:133761820 G/A cg08754478 chr10:133766260 PPP2R2D -0.54 -8.0 -0.4 1.97e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10078 0.528 rs2434697 chr5:466811 T/C cg26072250 chr5:443457 EXOC3;C5orf55 0.76 10.21 0.48 1.53e-21 Fat distribution (HIV); LIHC cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg20090690 chr10:134436459 INPP5A 0.43 5.95 0.31 6.52e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504073 0.647 rs10435612 chr8:49993696 A/T cg00325661 chr8:49890786 NA 0.33 7.64 0.38 2.15e-13 Blood metabolite ratios; LIHC cis rs9549367 0.577 rs3024718 chr13:113813853 C/T cg18105134 chr13:113819100 PROZ 0.71 12.05 0.55 4e-28 Platelet distribution width; LIHC trans rs11039798 0.844 rs7126949 chr11:48972166 A/G cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg09904177 chr6:26538194 HMGN4 0.57 11.56 0.53 2.66e-26 Intelligence (multi-trait analysis); LIHC cis rs477895 0.713 rs12787852 chr11:63954648 G/A cg04317338 chr11:64019027 PLCB3 0.85 10.2 0.48 1.73e-21 Mean platelet volume; LIHC cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg03264133 chr6:25882463 NA -0.47 -7.24 -0.36 3.06e-12 Height; LIHC cis rs7249142 0.573 rs2238668 chr19:19282597 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.27 -0.32 1.11e-9 IgG glycosylation; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg00800038 chr16:89945340 TCF25 -0.61 -9.65 -0.46 1.19e-19 Skin colour saturation; LIHC cis rs7618501 1.000 rs4855867 chr3:49745822 C/T cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.502 rs12365889 chr11:49623034 G/A cg15704280 chr7:45808275 SEPT13 -0.79 -11.8 -0.54 3.49e-27 Height; LIHC cis rs743757 1.000 rs2282754 chr3:50436827 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.46 7.06 0.36 9.34e-12 Diastolic blood pressure; LIHC cis rs8062405 0.755 rs4788073 chr16:28594549 A/G cg16576597 chr16:28551801 NUPR1 0.47 7.37 0.37 1.33e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7520050 0.931 rs11211198 chr1:46282673 G/A cg03146154 chr1:46216737 IPP -0.4 -6.55 -0.33 2.11e-10 Red blood cell count;Reticulocyte count; LIHC cis rs12824058 0.678 rs11614163 chr12:130814621 C/G cg26677194 chr12:130822605 PIWIL1 0.49 6.63 0.34 1.3e-10 Menopause (age at onset); LIHC cis rs2075371 0.829 rs11770764 chr7:134003308 T/C cg20476274 chr7:133979776 SLC35B4 0.68 9.3 0.45 1.69e-18 Mean platelet volume; LIHC cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg13047869 chr3:10149882 C3orf24 0.5 6.43 0.33 4.4e-10 Alzheimer's disease; LIHC cis rs6754311 0.551 rs9287442 chr2:136522710 A/G cg15123519 chr2:136567270 LCT 0.37 7.03 0.36 1.14e-11 Mosquito bite size; LIHC cis rs7707921 1.000 rs749402 chr5:81561325 C/T cg15871215 chr5:81402204 ATG10 -0.59 -5.85 -0.3 1.18e-8 Breast cancer; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg07701084 chr6:150067640 NUP43 0.36 6.64 0.34 1.22e-10 Lung cancer; LIHC cis rs7635838 0.785 rs2606738 chr3:11396562 T/C cg00170343 chr3:11313890 ATG7 0.48 7.57 0.38 3.41e-13 HDL cholesterol; LIHC cis rs506338 0.517 rs12269736 chr11:64471986 T/C cg27209729 chr11:64428925 NRXN2 0.38 7.07 0.36 8.58e-12 Body mass index;Urate levels; LIHC cis rs9916302 0.904 rs8079355 chr17:37473018 G/A cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC cis rs7086627 0.506 rs10749575 chr10:82136921 C/T cg00277334 chr10:82204260 NA -0.59 -9.32 -0.45 1.48e-18 Post bronchodilator FEV1; LIHC cis rs56235845 0.694 rs6875461 chr5:176754665 C/T cg16006841 chr5:176797999 RGS14 -0.57 -7.7 -0.38 1.51e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs9596863 0.898 rs9316660 chr13:54353562 T/C ch.13.53330881F chr13:54432880 NA 0.45 6.04 0.31 3.93e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9393777 0.623 rs7773938 chr6:26474044 C/T cg12826209 chr6:26865740 GUSBL1 0.68 7.32 0.37 1.75e-12 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.954 rs6849171 chr4:120409549 G/A cg25214090 chr10:38739885 LOC399744 0.57 9.37 0.45 1.01e-18 Corneal astigmatism; LIHC cis rs1801251 0.752 rs2675966 chr2:233735543 T/C cg08000102 chr2:233561755 GIGYF2 -0.71 -10.63 -0.5 5.24e-23 Coronary artery disease; LIHC cis rs11105298 0.891 rs10858889 chr12:89902604 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.59 -0.38 3.13e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1008375 1.000 rs9991307 chr4:17662408 A/G cg02297831 chr4:17616191 MED28 0.42 6.56 0.33 1.98e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02767759 chr16:30366751 CD2BP2 0.49 6.64 0.34 1.22e-10 Pancreatic cancer; LIHC trans rs1998584 1.000 rs10961199 chr9:13714854 G/T cg13665852 chr10:13146898 OPTN 0.41 6.16 0.32 2.02e-9 Survival in microsatellite instability low/stable colorectal cancer; LIHC cis rs7188697 0.809 rs4784956 chr16:58596291 A/C cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg01765077 chr12:122356316 WDR66 0.44 6.64 0.34 1.25e-10 Mean corpuscular volume; LIHC trans rs875971 0.545 rs6950988 chr7:65976415 C/T cg26939375 chr7:64535504 NA 0.4 6.3 0.32 9.05e-10 Aortic root size; LIHC cis rs7772486 0.875 rs2814876 chr6:146304030 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.34 -0.32 7.28e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs559928 0.606 rs7941773 chr11:63952759 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 7.63 0.38 2.3e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs644799 1.000 rs10831431 chr11:95510089 C/T cg25478527 chr11:95522999 CEP57;FAM76B 0.41 5.78 0.3 1.68e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs597539 0.652 rs546382 chr11:68704264 C/T cg06028808 chr11:68637592 NA 0.45 5.77 0.3 1.79e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs4900538 0.855 rs12586378 chr14:102853150 T/C cg18135206 chr14:102964638 TECPR2 -0.71 -11.02 -0.51 2.19e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10504229 0.610 rs6987118 chr8:58147851 G/T cg02290350 chr8:58132656 NA 0.44 9.39 0.45 8.42e-19 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.720 rs7752286 chr6:146072662 C/T cg05347473 chr6:146136440 FBXO30 -0.37 -5.99 -0.31 5.38e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs79976124 0.797 rs78317899 chr6:66652896 C/A cg07460842 chr6:66804631 NA 0.65 6.88 0.35 2.89e-11 Type 2 diabetes; LIHC cis rs10751667 0.643 rs7394524 chr11:933865 T/C cg06064525 chr11:970664 AP2A2 -0.55 -14.76 -0.62 1.8e-38 Alzheimer's disease (late onset); LIHC cis rs5769707 0.839 rs73176988 chr22:49989649 G/T cg01652190 chr22:50026171 C22orf34 -0.29 -6.61 -0.34 1.52e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2576037 0.899 rs12955429 chr18:44585484 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.12 -0.36 6.34e-12 Personality dimensions; LIHC cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 6.02e-12 Diabetic kidney disease; LIHC cis rs3008870 0.536 rs2208576 chr1:67513401 C/G cg08660285 chr1:67390436 MIER1;WDR78 -0.4 -6.9 -0.35 2.48e-11 Lymphocyte percentage of white cells; LIHC cis rs61990749 0.597 rs72685264 chr14:78152998 C/T cg21497246 chr14:78225524 SNW1;C14orf178 0.5 7.7 0.38 1.48e-13 Fibroblast growth factor basic levels; LIHC cis rs4555082 0.874 rs2816612 chr14:105723103 C/T cg06808227 chr14:105710500 BRF1 -0.55 -7.21 -0.36 3.58e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs910316 1.000 rs175449 chr14:75590846 A/T cg08847533 chr14:75593920 NEK9 -0.9 -19.49 -0.73 2.02e-57 Height; LIHC cis rs2073300 0.609 rs6137941 chr20:23400848 G/A cg16736954 chr20:23401023 NAPB 0.71 8.5 0.42 5.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs1814175 0.645 rs11040703 chr11:50024961 C/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs8084351 0.577 rs9946519 chr18:50631882 T/C cg24270629 chr18:50823537 DCC 0.43 6.5 0.33 2.82e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs427394 0.743 rs274716 chr5:6722289 T/C cg10857441 chr5:6722123 POLS -0.35 -6.04 -0.31 4.05e-9 Menopause (age at onset); LIHC cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg18876405 chr7:65276391 NA 0.56 9.37 0.45 1e-18 Calcium levels; LIHC cis rs11758351 0.866 rs77889957 chr6:26207435 A/G cg03854865 chr6:26224070 HIST1H3E 0.62 7.11 0.36 6.65e-12 Gout;Renal underexcretion gout; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26541587 chr10:43950885 ZNF487 -0.5 -6.08 -0.31 3.15e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.72 10.52 0.49 1.31e-22 Lymphocyte counts; LIHC cis rs10751667 0.643 rs10902244 chr11:949981 A/G cg10932868 chr11:921992 NA 0.38 7.05 0.36 9.7e-12 Alzheimer's disease (late onset); LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg07725925 chr16:89976287 TCF25 0.44 6.03 0.31 4.15e-9 Skin colour saturation; LIHC cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.3 0.45 1.74e-18 Bipolar disorder; LIHC cis rs9911578 1.000 rs8076121 chr17:57041699 G/A cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.52e-50 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs12086130 0.892 rs57331401 chr1:51451372 G/A cg07174182 chr1:51127561 FAF1 -0.92 -9.87 -0.47 2.14e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs4820539 1.000 rs916584 chr22:23469433 A/G cg14186256 chr22:23484241 RTDR1 0.97 20.99 0.75 1.91e-63 Bone mineral density; LIHC cis rs61677309 1.000 rs12576941 chr11:118158002 A/G cg06090739 chr11:118230722 UBE4A 0.36 6.77 0.34 5.64e-11 Lung cancer in ever smokers; LIHC cis rs2412488 1.000 rs3811782 chr4:54243905 T/C cg22241045 chr4:54363911 LNX1 -0.46 -7.29 -0.37 2.2e-12 DNA methylation (variation); LIHC cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg00343986 chr7:65444356 GUSB 0.44 6.26 0.32 1.18e-9 Aortic root size; LIHC cis rs2279817 0.863 rs12729433 chr1:18013089 C/G cg21791023 chr1:18019539 ARHGEF10L -0.44 -5.98 -0.31 5.78e-9 Neuroticism; LIHC cis rs34779708 0.801 rs12255409 chr10:35535425 G/A cg03585969 chr10:35415529 CREM 0.78 11.47 0.53 5.49e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9296092 0.538 rs76589475 chr6:33519517 G/C cg13560919 chr6:33536144 NA -0.38 -6.44 -0.33 4.1e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs12744310 0.887 rs12041352 chr1:41782781 T/G cg03962019 chr1:41807865 NA 0.39 6.23 0.32 1.38e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.99 0.31 5.4e-9 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27143824 chr4:184580738 C4orf41;RWDD4A 0.45 6.28 0.32 1.02e-9 Lung function (FEV1/FVC); LIHC cis rs2153535 0.601 rs7741024 chr6:8530313 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs55665837 0.519 rs10832297 chr11:14757737 C/A cg25251204 chr11:14927456 NA 0.4 5.74 0.3 2.11e-8 Vitamin D levels; LIHC cis rs7659604 0.605 rs1396080 chr4:122740454 T/G cg20573242 chr4:122745356 CCNA2 0.51 7.96 0.4 2.56e-14 Type 2 diabetes; LIHC cis rs7129556 0.520 rs4944164 chr11:77275849 G/A cg03570279 chr11:77446074 RSF1 -0.35 -6.51 -0.33 2.63e-10 Weight loss (gastric bypass surgery); LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg06558623 chr16:89946397 TCF25 0.88 13.65 0.59 3.7e-34 Skin colour saturation; LIHC cis rs6061231 0.724 rs1570027 chr20:60968596 A/G cg03945807 chr20:60948434 NA 0.4 5.77 0.3 1.76e-8 Colorectal cancer; LIHC cis rs34779708 0.966 rs17499247 chr10:35426755 A/G cg04310649 chr10:35416472 CREM -0.43 -5.86 -0.3 1.11e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs769267 0.965 rs2965198 chr19:19473030 A/G cg03709012 chr19:19516395 GATAD2A -0.99 -16.89 -0.67 5.71e-47 Tonsillectomy; LIHC cis rs6960043 1.000 rs12666046 chr7:15050381 A/G cg19272540 chr7:15055459 NA -0.23 -6.24 -0.32 1.32e-9 Type 2 diabetes; LIHC cis rs67311347 0.911 rs6776044 chr3:40377503 T/G cg16822855 chr3:40428330 ENTPD3 0.34 6.1 0.31 2.89e-9 Renal cell carcinoma; LIHC cis rs9640161 0.711 rs3735170 chr7:150034184 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.54 -8.75 -0.43 1e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs16854884 0.584 rs34372603 chr3:143738249 T/C cg06585982 chr3:143692056 C3orf58 0.55 7.17 0.36 4.79e-12 Economic and political preferences (feminism/equality); LIHC trans rs75804782 0.641 rs72983834 chr2:239319895 G/A cg01134436 chr17:81009848 B3GNTL1 0.81 6.59 0.34 1.69e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs77637988 0.533 rs13398791 chr2:48622320 G/C cg00032884 chr2:48540671 FOXN2 0.37 5.77 0.3 1.77e-8 Joint mobility (Beighton score); LIHC cis rs9527 0.501 rs12244388 chr10:104640052 G/A cg15744005 chr10:104629667 AS3MT -0.44 -10.08 -0.48 4.21e-21 Arsenic metabolism; LIHC cis rs4906332 0.966 rs12185021 chr14:103927805 A/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.18 -0.32 1.86e-9 Coronary artery disease; LIHC cis rs9430161 0.579 rs10864486 chr1:11040979 A/G cg02454025 chr1:11042201 C1orf127 0.74 13.39 0.59 3.52e-33 Ewing sarcoma; LIHC cis rs12530845 0.623 rs73721673 chr7:135349573 A/T cg23117316 chr7:135346802 PL-5283 -0.41 -5.9 -0.3 8.7e-9 Red blood cell traits; LIHC cis rs7208859 0.623 rs9906957 chr17:29157755 C/T cg14067834 chr17:29058358 SUZ12P 0.68 6.59 0.34 1.66e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2204008 0.806 rs1589382 chr12:38408565 T/A cg26384229 chr12:38710491 ALG10B 0.6 8.33 0.41 1.91e-15 Bladder cancer; LIHC cis rs36051895 0.589 rs10283734 chr9:5217139 A/T cg02405213 chr9:5042618 JAK2 -0.66 -10.52 -0.49 1.32e-22 Pediatric autoimmune diseases; LIHC cis rs2455799 0.574 rs2470534 chr3:15701054 C/G cg16303742 chr3:15540471 COLQ 0.35 5.87 0.3 1.02e-8 Mean platelet volume; LIHC cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.57 9.58 0.46 1.99e-19 Bipolar disorder; LIHC cis rs7116495 0.867 rs510925 chr11:71809500 C/T cg26138937 chr11:71823887 C11orf51 1.09 9.26 0.45 2.35e-18 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs76419734 0.510 rs2553463 chr4:106730663 C/T cg24545054 chr4:106630052 GSTCD;INTS12 -0.69 -7.3 -0.37 2.09e-12 Post bronchodilator FEV1; LIHC cis rs7769051 1.000 rs7765224 chr6:133101624 T/C cg22852734 chr6:133119734 C6orf192 0.94 9.28 0.45 1.95e-18 Type 2 diabetes nephropathy; LIHC cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC cis rs8020095 0.528 rs6573758 chr14:67667906 A/G cg03487553 chr14:67822707 ATP6V1D -0.35 -6.12 -0.31 2.52e-9 Depression (quantitative trait); LIHC cis rs922107 0.738 rs12411255 chr1:90036747 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.6 -0.38 2.8e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs1555399 0.935 rs7144624 chr14:67984109 G/T cg16224230 chr14:67978224 TMEM229B -0.25 -5.99 -0.31 5.46e-9 Parkinson's disease; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg06873352 chr17:61820015 STRADA -0.75 -13.09 -0.58 5.01e-32 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg00280220 chr17:61926910 NA 0.43 6.75 0.34 6.18e-11 Prudent dietary pattern; LIHC cis rs10504229 1.000 rs68114352 chr8:58196081 C/T cg02290350 chr8:58132656 NA 0.47 9.16 0.44 4.93e-18 Developmental language disorder (linguistic errors); LIHC cis rs7429990 0.932 rs11130155 chr3:48140428 A/C cg11946769 chr3:48343235 NME6 -0.48 -6.41 -0.33 4.81e-10 Educational attainment (years of education); LIHC cis rs6424115 0.830 rs2503002 chr1:24196957 C/G cg10978503 chr1:24200527 CNR2 0.34 8.36 0.41 1.65e-15 Immature fraction of reticulocytes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03262077 chr1:109505986 CLCC1 0.49 6.78 0.34 5.33e-11 Lung function (FEV1/FVC); LIHC cis rs7106204 0.920 rs7946615 chr11:24221036 T/C ch.11.24196551F chr11:24239977 NA 0.69 6.96 0.35 1.75e-11 Response to Homoharringtonine (cytotoxicity); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg25760338 chr6:52860082 GSTA4 -0.42 -6.28 -0.32 1.01e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs877282 1.000 rs12775643 chr10:773242 G/A cg22713356 chr15:30763199 NA 1.23 10.89 0.51 6.83e-24 Uric acid levels; LIHC cis rs1580019 0.961 rs1580022 chr7:32497712 C/A cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs28647808 0.748 rs28721280 chr9:136267318 C/G cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs12908161 0.960 rs34452033 chr15:85221993 A/G cg12863693 chr15:85201151 NMB 0.48 6.9 0.35 2.49e-11 Schizophrenia; LIHC cis rs921968 0.565 rs6745700 chr2:219639862 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs12765878 0.967 rs10883940 chr10:105650598 G/A cg11005552 chr10:105648138 OBFC1 0.39 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs9309711 0.643 rs10188449 chr2:3480366 T/C cg15506890 chr2:3487001 NA -0.48 -7.69 -0.38 1.53e-13 Neurofibrillary tangles; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg21548813 chr6:291882 DUSP22 -0.55 -7.37 -0.37 1.32e-12 Menopause (age at onset); LIHC cis rs4819052 0.851 rs2838848 chr21:46671017 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.33 0.52 1.82e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9768139 0.658 rs28425474 chr7:158116360 C/T cg25566285 chr7:158114605 PTPRN2 0.23 6.22 0.32 1.43e-9 Calcium levels; LIHC cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg03806693 chr22:41940476 POLR3H -1.12 -12.95 -0.57 1.75e-31 Vitiligo; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg02993280 chr1:107599747 PRMT6 0.64 10.12 0.48 3.04e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs870825 0.929 rs72689273 chr4:185592750 C/T cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs11673344 0.734 rs2551047 chr19:37426076 G/A cg27390819 chr19:37464633 NA -0.5 -6.03 -0.31 4.35e-9 Obesity-related traits; LIHC cis rs10461617 0.541 rs860581 chr5:56150537 A/G cg17801930 chr5:56009405 NA -0.43 -5.71 -0.3 2.41e-8 Type 2 diabetes; LIHC cis rs4908768 0.817 rs11587482 chr1:8743195 T/G cg25722041 chr1:8623473 RERE 0.43 5.85 0.3 1.16e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs11628318 0.803 rs10138267 chr14:103035432 C/T cg23461800 chr14:103021989 NA -0.5 -7.12 -0.36 6.6e-12 Platelet count; LIHC cis rs477895 1.000 rs7947143 chr11:64090422 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.01 0.35 1.28e-11 Mean platelet volume; LIHC cis rs1401999 1.000 rs6802849 chr3:183698943 A/C cg05044414 chr3:183734942 ABCC5 0.33 5.92 0.3 7.91e-9 Anterior chamber depth; LIHC cis rs11696845 0.626 rs1111032 chr20:43378770 A/G cg25301532 chr20:43378953 KCNK15 0.26 6.01 0.31 4.69e-9 Obesity-related traits; LIHC cis rs4423214 0.592 rs11234027 chr11:71234107 G/A cg05163923 chr11:71159392 DHCR7 -0.59 -7.2 -0.36 3.77e-12 Vitamin D levels; LIHC cis rs36051895 0.559 rs7868706 chr9:5210936 T/G cg02405213 chr9:5042618 JAK2 -0.61 -10.37 -0.49 4.49e-22 Pediatric autoimmune diseases; LIHC cis rs78545713 1.000 rs41266821 chr6:26247198 A/G cg16070018 chr6:26224392 HIST1H3E 0.69 7.32 0.37 1.79e-12 Iron status biomarkers (total iron binding capacity); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12980527 chr5:36875537 NIPBL -0.41 -6.29 -0.32 9.85e-10 Pancreatic cancer; LIHC cis rs7592578 0.771 rs62181034 chr2:191354963 C/A cg27211696 chr2:191398769 TMEM194B -0.59 -7.87 -0.39 4.86e-14 Diastolic blood pressure; LIHC cis rs10888574 1 rs10888574 chr1:150164058 A/G cg15654264 chr1:150340011 RPRD2 -0.4 -6.02 -0.31 4.48e-9 Pediatric bone mineral content (hip); LIHC cis rs2439831 0.867 rs6493085 chr15:43654182 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs1215050 0.904 rs1727285 chr4:98978821 G/A cg05340658 chr4:99064831 C4orf37 -0.41 -5.97 -0.31 5.97e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2282802 0.685 rs67813630 chr5:139623592 C/A cg26211634 chr5:139558579 C5orf32 0.4 6.14 0.31 2.33e-9 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.579 rs2504140 chr10:38387579 T/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs7107174 1.000 rs4128206 chr11:78015952 A/C cg02023728 chr11:77925099 USP35 0.46 8.79 0.43 7.44e-17 Testicular germ cell tumor; LIHC cis rs2050392 0.792 rs303434 chr10:30714440 G/A cg25182066 chr10:30743637 MAP3K8 -0.49 -8.08 -0.4 1.09e-14 Inflammatory bowel disease; LIHC cis rs2834188 1.000 rs2834190 chr21:34693011 A/T cg04842828 chr21:34696676 IFNAR1 -0.43 -5.84 -0.3 1.18e-8 Narcolepsy; LIHC cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg06238570 chr21:40685208 BRWD1 0.58 6.98 0.35 1.53e-11 Cognitive function; LIHC cis rs875971 0.862 rs6460293 chr7:65810192 C/A cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs12086130 0.892 rs12855 chr1:51440093 C/T cg07174182 chr1:51127561 FAF1 -0.76 -8.5 -0.42 6.13e-16 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs754466 0.561 rs67332822 chr10:79706118 G/A cg17075019 chr10:79541650 NA -0.52 -5.73 -0.3 2.17e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4654899 0.680 rs11805006 chr1:21249603 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.88 0.3 9.87e-9 Superior frontal gyrus grey matter volume; LIHC cis rs6831352 0.918 rs13110764 chr4:100062466 C/T cg12011299 chr4:100065546 ADH4 -0.54 -9.83 -0.47 3.09e-20 Alcohol dependence; LIHC trans rs61931739 0.534 rs10506120 chr12:34235603 G/A cg26384229 chr12:38710491 ALG10B 0.57 7.38 0.37 1.2e-12 Morning vs. evening chronotype; LIHC cis rs611744 0.967 rs685690 chr8:109192145 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs9303401 0.659 rs11495824 chr17:56918882 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.58 0.59 6.99e-34 Cognitive test performance; LIHC cis rs875971 0.798 rs12698522 chr7:65967341 T/C cg18252515 chr7:66147081 NA -0.46 -6.79 -0.34 4.96e-11 Aortic root size; LIHC cis rs807669 0.557 rs712958 chr22:19167409 T/C cg02655711 chr22:19163373 SLC25A1 0.36 6.13 0.31 2.44e-9 Metabolite levels; LIHC cis rs7412746 0.658 rs2089082 chr1:150800090 T/G cg18016565 chr1:150552671 MCL1 0.54 10.25 0.48 1.12e-21 Melanoma; LIHC cis rs4908760 0.792 rs6577515 chr1:8714202 G/C cg20416874 chr1:8611966 RERE -0.66 -13.58 -0.59 7.04e-34 Vitiligo; LIHC trans rs2739330 0.760 rs5760095 chr22:24247293 A/G cg06437703 chr8:37914619 EIF4EBP1 -0.59 -8.99 -0.44 1.77e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2404602 0.622 rs4886506 chr15:77207277 G/T cg03037974 chr15:76606532 NA 0.57 9.81 0.47 3.65e-20 Blood metabolite levels; LIHC cis rs9430161 0.579 rs10864486 chr1:11040979 A/G cg27631724 chr1:11040367 C1orf127 0.39 7.82 0.39 6.42e-14 Ewing sarcoma; LIHC cis rs4843747 0.671 rs72818576 chr16:88111019 C/G cg06050784 chr16:88016603 BANP 0.35 6.43 0.33 4.33e-10 Menopause (age at onset); LIHC cis rs2228479 0.717 rs11649210 chr16:89807233 C/G cg06558623 chr16:89946397 TCF25 0.8 11.1 0.51 1.18e-24 Skin colour saturation; LIHC cis rs754466 0.874 rs55910200 chr10:79665173 T/C cg17075019 chr10:79541650 NA -0.63 -8.49 -0.42 6.49e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8084351 0.560 rs12456646 chr18:50668785 C/T cg24270629 chr18:50823537 DCC -0.44 -6.5 -0.33 2.8e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs10751667 0.666 rs10794347 chr11:939863 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.97 -0.63 2.48e-39 Alzheimer's disease (late onset); LIHC cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg11764359 chr7:65958608 NA 0.58 6.04 0.31 3.97e-9 Diabetic kidney disease; LIHC trans rs916888 0.697 rs199516 chr17:44856485 C/T cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs17376456 0.877 rs10070390 chr5:93452345 G/A cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg08888203 chr3:10149979 C3orf24 0.53 6.46 0.33 3.67e-10 Alzheimer's disease; LIHC cis rs7072216 0.727 rs10748728 chr10:100171198 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs1005277 0.691 rs2474558 chr10:38486141 A/C cg18963800 chr10:38644991 HSD17B7P2 0.43 6.17 0.32 1.94e-9 Extrinsic epigenetic age acceleration; LIHC cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.96 0.31 6.17e-9 Bipolar disorder; LIHC cis rs6951245 0.935 rs112554101 chr7:1065535 A/G cg24642844 chr7:1081250 C7orf50 -0.73 -8.02 -0.4 1.65e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7552404 0.807 rs2066183 chr1:76153745 A/G cg10523679 chr1:76189770 ACADM 0.67 9.93 0.47 1.34e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs3106136 0.710 rs6856971 chr4:95296041 C/T cg11021082 chr4:95130006 SMARCAD1 -0.35 -6.09 -0.31 3.1e-9 Capecitabine sensitivity; LIHC trans rs2262909 0.962 rs1526884 chr19:22303651 A/G cg05197062 chr11:11642011 GALNTL4 0.46 6.73 0.34 7.11e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs6570726 0.935 rs374000 chr6:145855290 C/T cg23711669 chr6:146136114 FBXO30 0.56 10.01 0.48 7.29e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs7539409 0.651 rs979757 chr1:84296605 T/C cg10977910 chr1:84465055 TTLL7 0.69 7.01 0.35 1.31e-11 Alzheimer's disease; LIHC trans rs877282 0.842 rs7092986 chr10:756373 G/A cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg13047869 chr3:10149882 C3orf24 0.54 6.41 0.33 4.82e-10 Alzheimer's disease; LIHC cis rs2153535 0.601 rs1855765 chr6:8444325 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg02475777 chr4:1388615 CRIPAK -0.5 -7.47 -0.37 6.86e-13 Obesity-related traits; LIHC cis rs2834188 1.000 rs9982088 chr21:34686841 A/G cg04842828 chr21:34696676 IFNAR1 0.46 6.16 0.32 2.02e-9 Narcolepsy; LIHC cis rs7903847 0.656 rs61861861 chr10:99143619 C/T cg06359132 chr10:99160096 RRP12 -0.41 -6.05 -0.31 3.71e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1005277 0.579 rs1740749 chr10:38521646 A/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg14983838 chr19:29218262 NA 0.47 7.43 0.37 8.5e-13 Methadone dose in opioid dependence; LIHC cis rs3960554 0.569 rs10464565 chr7:75869526 T/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.23 -0.36 3.13e-12 Eotaxin levels; LIHC cis rs9517313 0.551 rs2274051 chr13:99091634 A/G cg20487152 chr13:99095054 FARP1 0.45 8.0 0.4 1.98e-14 Neuroticism; LIHC cis rs9549367 0.789 rs9549699 chr13:113878263 T/A cg00898013 chr13:113819073 PROZ -0.41 -7.2 -0.36 3.78e-12 Platelet distribution width; LIHC cis rs7572733 0.555 rs7590828 chr2:198940251 A/G cg10820045 chr2:198174542 NA -0.41 -6.16 -0.32 2.06e-9 Dermatomyositis; LIHC cis rs6688613 0.685 rs4657613 chr1:166870878 A/G cg07049167 chr1:166818506 POGK 0.4 6.21 0.32 1.5e-9 Refractive astigmatism; LIHC cis rs6840360 0.615 rs12641438 chr4:152607586 A/G cg22705602 chr4:152727874 NA -0.33 -6.84 -0.35 3.57e-11 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.731 rs7108376 chr11:68347870 A/G cg01657329 chr11:68192670 LRP5 0.5 7.38 0.37 1.19e-12 Total body bone mineral density; LIHC cis rs6722750 0.818 rs13411753 chr2:64394417 A/G cg22352474 chr2:64371530 PELI1 0.46 6.67 0.34 1.05e-10 Neuroticism; LIHC cis rs16854884 0.586 rs7642551 chr3:143732167 C/T cg06585982 chr3:143692056 C3orf58 0.57 7.43 0.37 8.67e-13 Economic and political preferences (feminism/equality); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27619136 chr4:174291353 SAP30 0.44 6.86 0.35 3.24e-11 Cognitive function; LIHC cis rs2295359 0.892 rs72676069 chr1:67658954 T/C cg12940439 chr1:67600707 NA 0.34 5.82 0.3 1.38e-8 Psoriasis; LIHC cis rs6977660 1.000 rs10260360 chr7:19792824 T/C cg07541023 chr7:19748670 TWISTNB 0.4 6.19 0.32 1.71e-9 Thyroid stimulating hormone; LIHC cis rs11122272 0.735 rs2247124 chr1:231493687 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.26 0.45 2.26e-18 Hemoglobin concentration; LIHC cis rs6840360 1.000 rs28710456 chr4:152667171 T/C cg22705602 chr4:152727874 NA -0.34 -7.21 -0.36 3.69e-12 Intelligence (multi-trait analysis); LIHC cis rs782590 0.837 rs782585 chr2:55922930 C/T cg03859395 chr2:55845619 SMEK2 0.88 15.01 0.63 1.72e-39 Metabolic syndrome; LIHC cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg22907277 chr7:1156413 C7orf50 0.55 8.28 0.41 2.76e-15 Longevity;Endometriosis; LIHC cis rs2976388 0.590 rs10110970 chr8:143820410 G/C cg06565975 chr8:143823917 SLURP1 -0.41 -7.72 -0.39 1.27e-13 Urinary tract infection frequency; LIHC cis rs12101261 0.536 rs724170 chr14:81457940 G/A cg06600135 chr14:81408086 NA 0.41 7.27 0.37 2.52e-12 Graves' disease; LIHC cis rs10411936 0.626 rs8113060 chr19:16596795 G/C cg10248733 chr19:16607483 C19orf44;CALR3 0.52 6.95 0.35 1.81e-11 White blood cell count;Multiple sclerosis; LIHC cis rs8072100 0.576 rs12948299 chr17:45403057 T/C cg08085267 chr17:45401833 C17orf57 -0.62 -8.45 -0.42 8.66e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2421770 0.530 rs3847622 chr11:35368700 A/G cg13971030 chr11:35366721 SLC1A2 0.45 7.63 0.38 2.36e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs4555082 0.957 rs2816629 chr14:105737261 G/A cg06808227 chr14:105710500 BRF1 -0.62 -8.74 -0.43 1.08e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs13108904 0.539 rs13140926 chr4:1340939 G/A cg22903657 chr4:1355424 KIAA1530 -0.43 -6.3 -0.32 9.4e-10 Obesity-related traits; LIHC cis rs9814567 0.806 rs7626557 chr3:134318213 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.59 -9.59 -0.46 1.86e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9303401 0.625 rs34963822 chr17:56988424 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.6 0.56 3.73e-30 Cognitive test performance; LIHC cis rs899997 1.000 rs9888691 chr15:79010046 T/C cg04896959 chr15:78267971 NA 0.4 7.82 0.39 6.82e-14 Coronary artery disease or large artery stroke; LIHC trans rs4714291 0.832 rs9471247 chr6:40105318 A/G cg02267698 chr19:7991119 CTXN1 -0.4 -6.59 -0.34 1.63e-10 Strep throat; LIHC cis rs9583531 0.689 rs2165418 chr13:111379365 G/T cg24331049 chr13:111365604 ING1 -0.78 -13.04 -0.58 7.7e-32 Coronary artery disease; LIHC cis rs6840360 1.000 rs4696284 chr4:152595836 C/G cg22705602 chr4:152727874 NA -0.3 -6.45 -0.33 3.71e-10 Intelligence (multi-trait analysis); LIHC cis rs8020095 0.571 rs8022657 chr14:67390499 C/T cg03487553 chr14:67822707 ATP6V1D -0.36 -6.16 -0.32 2.02e-9 Depression (quantitative trait); LIHC cis rs9556958 0.708 rs9513435 chr13:99160334 C/G cg20750642 chr13:99100586 FARP1 0.34 6.44 0.33 4.08e-10 Educational attainment (years of education); LIHC cis rs2204008 0.777 rs2049130 chr12:38444837 G/A cg26384229 chr12:38710491 ALG10B 0.58 8.25 0.41 3.52e-15 Bladder cancer; LIHC cis rs7619427 0.908 rs9816229 chr3:44080077 T/C cg24966902 chr3:44043705 NA 0.43 6.19 0.32 1.69e-9 Schizophrenia; LIHC cis rs7572733 0.515 rs700675 chr2:198700216 G/A cg00792783 chr2:198669748 PLCL1 0.46 6.77 0.34 5.79e-11 Dermatomyositis; LIHC cis rs151997 0.671 rs27907 chr5:50193797 C/G cg06027927 chr5:50259733 NA 0.44 6.55 0.33 2.12e-10 Callous-unemotional behaviour; LIHC cis rs796364 0.806 rs11684942 chr2:201009136 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs61990749 0.597 rs10148373 chr14:78280199 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.63 9.59 0.46 1.87e-19 Fibroblast growth factor basic levels; LIHC trans rs66887589 0.616 rs10032299 chr4:120206419 C/T cg25214090 chr10:38739885 LOC399744 0.44 6.95 0.35 1.9e-11 Diastolic blood pressure; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18679782 chr19:10216839 SNORD105;PPAN-P2RY11;PPAN -0.53 -6.11 -0.31 2.76e-9 Systolic blood pressure; LIHC cis rs826838 0.967 rs826870 chr12:39120250 G/A cg26384229 chr12:38710491 ALG10B -0.63 -9.31 -0.45 1.61e-18 Heart rate; LIHC cis rs2204008 0.774 rs11520237 chr12:38266978 G/A cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.57e-21 Bladder cancer; LIHC cis rs7927592 0.871 rs12360903 chr11:68236314 C/A cg20283391 chr11:68216788 NA -0.52 -7.79 -0.39 7.98e-14 Total body bone mineral density; LIHC cis rs703842 1.000 rs11172351 chr12:58213485 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.86 13.87 0.6 5.03e-35 Multiple sclerosis; LIHC trans rs1814175 0.817 rs6486046 chr11:49997017 T/C cg03929089 chr4:120376271 NA -0.88 -18.29 -0.7 1.33e-52 Height; LIHC cis rs10751667 1.000 rs7395691 chr11:985006 T/C ch.11.42038R chr11:967971 AP2A2 0.59 10.88 0.51 6.99e-24 Alzheimer's disease (late onset); LIHC cis rs3820068 0.581 rs16851855 chr1:15930869 G/A cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs743757 0.697 rs763030 chr3:50528092 G/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.44 6.57 0.33 1.86e-10 Diastolic blood pressure; LIHC cis rs7100689 0.577 rs2185427 chr10:82056667 G/T cg01528321 chr10:82214614 TSPAN14 -0.88 -11.94 -0.54 1.03e-27 Post bronchodilator FEV1; LIHC cis rs36051895 0.530 rs2093447 chr9:5230374 G/T cg02405213 chr9:5042618 JAK2 -0.61 -8.95 -0.44 2.35e-17 Pediatric autoimmune diseases; LIHC cis rs2976388 0.647 rs2585154 chr8:143783485 C/T cg06565975 chr8:143823917 SLURP1 0.34 6.41 0.33 4.81e-10 Urinary tract infection frequency; LIHC cis rs992157 1.000 rs11554825 chr2:219125809 C/T cg00012203 chr2:219082015 ARPC2 0.91 15.08 0.63 9.78e-40 Colorectal cancer; LIHC cis rs72615157 0.612 rs7786505 chr7:99817585 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.54 5.98 0.31 5.49e-9 Lung function (FEV1/FVC); LIHC cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.92 -9.23 -0.45 2.85e-18 Platelet count; LIHC cis rs11971779 0.774 rs7785906 chr7:139122652 T/C cg07862535 chr7:139043722 LUC7L2 0.6 9.83 0.47 2.9e-20 Diisocyanate-induced asthma; LIHC cis rs9303401 0.659 rs17222523 chr17:56620501 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.13 0.58 3.52e-32 Cognitive test performance; LIHC cis rs9443189 1.000 rs1280044 chr6:76522602 A/G cg01950844 chr6:76311363 SENP6 -0.5 -6.35 -0.32 6.97e-10 Prostate cancer; LIHC cis rs249954 0.512 rs249867 chr16:23668568 G/A cg09867953 chr16:23706666 ERN2 0.37 6.19 0.32 1.76e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7264396 0.790 rs2425097 chr20:34308926 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.74 -0.54 5.89e-27 Total cholesterol levels; LIHC trans rs7618501 1.000 rs9872864 chr3:49792023 A/G cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.6 -0.34 1.58e-10 Intelligence (multi-trait analysis); LIHC cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg27572855 chr1:25598939 RHD 0.41 8.88 0.43 3.87e-17 Plateletcrit;Mean corpuscular volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18017109 chr1:10458942 PGD 0.41 6.15 0.32 2.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12644436 0.534 rs34644026 chr4:88784821 A/G cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs7258465 1.000 rs4808804 chr19:18585325 A/G cg01065977 chr19:18549689 ISYNA1 -0.37 -5.72 -0.3 2.3e-8 Breast cancer; LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg00091569 chr3:40428383 ENTPD3 0.39 6.61 0.34 1.45e-10 Renal cell carcinoma; LIHC cis rs7520050 0.931 rs6697557 chr1:46307809 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs700651 0.821 rs771005 chr2:198675948 C/T cg03934865 chr2:198174659 NA 0.46 6.58 0.34 1.74e-10 Intracranial aneurysm; LIHC cis rs2072499 0.966 rs2842869 chr1:156160696 A/G cg25208724 chr1:156163844 SLC25A44 0.94 15.95 0.65 3.43e-43 Testicular germ cell tumor; LIHC cis rs2839186 0.867 rs13050387 chr21:47701423 C/T cg12379764 chr21:47803548 PCNT -0.6 -8.77 -0.43 8.27e-17 Testicular germ cell tumor; LIHC cis rs9522267 0.535 rs2039915 chr13:112238794 C/T cg10483660 chr13:112241077 NA -0.22 -5.84 -0.3 1.21e-8 Hepatitis; LIHC cis rs2257205 0.588 rs7214266 chr17:56851920 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -6.61 -0.34 1.5e-10 Pancreatic cancer; LIHC cis rs11971779 0.666 rs6467847 chr7:139079436 T/C cg07862535 chr7:139043722 LUC7L2 0.55 9.4 0.45 8.36e-19 Diisocyanate-induced asthma; LIHC cis rs7208859 0.673 rs11650305 chr17:29229361 A/C cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1499614 1.000 rs1267817 chr7:66110040 G/T cg10756647 chr7:56101905 PSPH 1.01 11.79 0.54 3.67e-27 Gout; LIHC cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg11764359 chr7:65958608 NA 0.69 9.38 0.45 9.59e-19 Aortic root size; LIHC cis rs722599 0.501 rs10139347 chr14:75390135 T/C cg11812906 chr14:75593930 NEK9 0.46 7.77 0.39 9e-14 IgG glycosylation; LIHC cis rs796364 0.806 rs78527234 chr2:200913453 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs561341 0.700 rs6505266 chr17:30225813 G/A cg13647721 chr17:30228624 UTP6 0.78 8.98 0.44 1.8e-17 Hip circumference adjusted for BMI; LIHC cis rs9814567 1.000 rs6802654 chr3:134217072 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.13 -0.55 2.01e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1552244 0.744 rs6763366 chr3:10033544 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.69 0.46 9.08e-20 Alzheimer's disease; LIHC cis rs79976124 0.760 rs74295030 chr6:66654441 T/C cg07460842 chr6:66804631 NA 0.65 6.88 0.35 2.89e-11 Type 2 diabetes; LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg00656387 chr3:40428638 ENTPD3 0.48 7.89 0.39 4.06e-14 Renal cell carcinoma; LIHC cis rs9768139 0.733 rs13309408 chr7:158122261 C/T cg25566285 chr7:158114605 PTPRN2 0.23 6.16 0.32 2.04e-9 Calcium levels; LIHC cis rs422249 0.634 rs174610 chr11:61627833 A/G cg27386326 chr11:61587980 NA 0.36 6.54 0.33 2.19e-10 Trans fatty acid levels; LIHC cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg16405210 chr4:1374714 KIAA1530 0.79 11.35 0.52 1.5e-25 Longevity; LIHC cis rs67460515 0.892 rs73026974 chr3:160963231 A/C cg17135325 chr3:160939158 NMD3 0.55 7.84 0.39 5.59e-14 Parkinson's disease; LIHC cis rs5753037 0.838 rs28749829 chr22:30219326 C/T cg01021169 chr22:30184971 ASCC2 -0.34 -6.45 -0.33 3.75e-10 Type 1 diabetes; LIHC cis rs875971 0.545 rs73142245 chr7:65691649 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.31 0.37 1.86e-12 Aortic root size; LIHC trans rs4650994 0.544 rs6675811 chr1:178499068 T/A cg05059571 chr16:84539110 KIAA1609 -0.41 -7.06 -0.36 9.58e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2075371 1.000 rs2598291 chr7:133988313 C/G cg11752832 chr7:134001865 SLC35B4 0.53 8.07 0.4 1.18e-14 Mean platelet volume; LIHC cis rs9902453 0.967 rs9904336 chr17:28357080 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs9549367 0.756 rs2316463 chr13:113901406 C/T cg00898013 chr13:113819073 PROZ -0.43 -7.29 -0.37 2.18e-12 Platelet distribution width; LIHC cis rs7223966 0.960 rs7212379 chr17:61706122 G/A cg05941027 chr17:61774174 LIMD2 0.3 6.2 0.32 1.65e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6062302 0.522 rs2282157 chr20:62227180 C/G cg16989086 chr20:62203971 PRIC285 0.57 8.2 0.41 5.08e-15 Glioblastoma; LIHC cis rs8060686 0.641 rs12445396 chr16:68155121 G/A cg05110241 chr16:68378359 PRMT7 -0.6 -6.78 -0.34 5.41e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 8.27 0.41 2.94e-15 Platelet count; LIHC cis rs1568889 1.000 rs11603799 chr11:28196488 T/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.52 7.22 0.36 3.34e-12 Bipolar disorder; LIHC trans rs1005277 0.579 rs2474569 chr10:38383491 C/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs362296 0.698 rs3135172 chr4:3258735 A/G cg06533319 chr4:3265114 C4orf44 0.32 5.73 0.3 2.26e-8 Parental longevity (mother's age at death); LIHC cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg04352962 chr1:209979756 IRF6 0.4 6.22 0.32 1.49e-9 Cleft lip with or without cleft palate; LIHC cis rs7107174 0.892 rs11237477 chr11:78095069 A/T cg02023728 chr11:77925099 USP35 0.4 7.56 0.38 3.69e-13 Testicular germ cell tumor; LIHC cis rs4638749 0.677 rs4676186 chr2:108842640 T/C cg25838818 chr2:108905173 SULT1C2 -0.4 -7.03 -0.36 1.15e-11 Blood pressure; LIHC cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.42 0.45 7.02e-19 Bipolar disorder; LIHC cis rs11122272 0.735 rs2790891 chr1:231513190 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs782590 0.807 rs782642 chr2:55928444 G/T cg18811423 chr2:55921094 PNPT1 1.03 16.92 0.67 4.42e-47 Metabolic syndrome; LIHC cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg00656387 chr3:40428638 ENTPD3 0.44 7.16 0.36 4.81e-12 Renal cell carcinoma; LIHC cis rs17401966 1.000 rs7520651 chr1:10329872 G/A cg19773385 chr1:10388646 KIF1B -0.48 -8.36 -0.41 1.65e-15 Hepatocellular carcinoma; LIHC cis rs2070488 1.000 rs4147024 chr3:38456664 C/T cg24069376 chr3:38537580 EXOG 0.43 7.9 0.39 3.93e-14 Electrocardiographic conduction measures; LIHC cis rs55665837 0.519 rs10832297 chr11:14757737 C/A cg19336497 chr11:14380999 RRAS2 -0.34 -5.74 -0.3 2.13e-8 Vitamin D levels; LIHC cis rs55702914 0.935 rs17405525 chr2:198214183 C/G cg10820045 chr2:198174542 NA -0.38 -5.73 -0.3 2.24e-8 Major depression and alcohol dependence; LIHC cis rs875971 0.545 rs3735147 chr7:65970528 A/C cg11764359 chr7:65958608 NA 0.58 8.22 0.41 4.2e-15 Aortic root size; LIHC cis rs5753618 0.561 rs2413047 chr22:31666026 A/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs365132 0.875 rs547798 chr5:176326721 C/A cg16309518 chr5:176445507 NA -0.51 -9.11 -0.44 7.04e-18 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs600806 0.815 rs4970758 chr1:109979617 A/G cg23091122 chr1:110024289 SYPL2 -0.49 -6.49 -0.33 2.97e-10 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.832 rs3732968 chr3:10013273 A/G cg00149659 chr3:10157352 C3orf10 0.53 6.1 0.31 2.93e-9 Alzheimer's disease; LIHC cis rs6121246 0.909 rs6119725 chr20:30385557 G/T cg13852791 chr20:30311386 BCL2L1 0.92 9.63 0.46 1.39e-19 Mean corpuscular hemoglobin; LIHC cis rs921968 0.643 rs484085 chr2:219396684 C/T cg18887096 chr2:219472410 PLCD4 0.36 6.44 0.33 4.12e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs77861329 1.000 rs876782 chr3:52107909 C/T cg08692210 chr3:52188851 WDR51A -0.83 -8.64 -0.42 2.25e-16 Macrophage inflammatory protein 1b levels; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg02581963 chr10:102133317 C10orf75 -0.44 -6.77 -0.34 5.7e-11 Morning vs. evening chronotype; LIHC cis rs10791097 0.694 rs1893018 chr11:130756632 T/C cg22079354 chr11:130786696 SNX19 0.41 5.82 0.3 1.35e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg25072359 chr17:41440525 NA 0.38 6.03 0.31 4.34e-9 Menopause (age at onset); LIHC cis rs2120019 1.000 rs34237279 chr15:75361121 A/G cg09165964 chr15:75287851 SCAMP5 -0.65 -10.51 -0.49 1.47e-22 Blood trace element (Zn levels); LIHC cis rs1387259 0.690 rs1601985 chr12:48761914 A/G cg21466736 chr12:48725269 NA -0.62 -9.15 -0.44 5.19e-18 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs2439831 0.850 rs7181039 chr15:44179112 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.29 0.32 9.87e-10 Lung cancer in ever smokers; LIHC cis rs7927592 0.763 rs596494 chr11:68251054 T/G cg01657329 chr11:68192670 LRP5 -0.47 -6.93 -0.35 2.12e-11 Total body bone mineral density; LIHC cis rs9768139 0.634 rs11762383 chr7:158113889 C/T cg25566285 chr7:158114605 PTPRN2 0.22 6.03 0.31 4.25e-9 Calcium levels; LIHC cis rs2629540 0.765 rs7097177 chr10:126539839 A/G cg08799069 chr10:126477246 METTL10 -0.49 -8.26 -0.41 3.17e-15 Cocaine dependence; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg20908993 chr14:67826378 EIF2S1;ATP6V1D -0.42 -6.19 -0.32 1.71e-9 Body mass index; LIHC cis rs372883 0.648 rs368322 chr21:30717151 C/T cg08807101 chr21:30365312 RNF160 -0.5 -5.71 -0.3 2.42e-8 Pancreatic cancer; LIHC cis rs559928 0.606 rs56311067 chr11:63931607 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.4 0.37 1.06e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs1865760 0.566 rs10807006 chr6:26048752 C/A cg18357526 chr6:26021779 HIST1H4A 0.48 7.06 0.36 9.55e-12 Height; LIHC cis rs7178375 1.000 rs35162264 chr15:31200683 T/A cg19680485 chr15:31195859 MTMR15 -0.53 -5.88 -0.3 9.68e-9 Hypertriglyceridemia; LIHC cis rs10916814 1.000 rs7365904 chr1:20904528 G/A cg24502330 chr1:20914028 CDA -0.3 -6.1 -0.31 2.8e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1997103 0.954 rs10246216 chr7:55390479 C/T cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.39e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9905704 0.671 rs28709536 chr17:57008912 C/A cg05425664 chr17:57184151 TRIM37 -0.44 -6.16 -0.32 2e-9 Testicular germ cell tumor; LIHC cis rs7528419 1.000 rs12740374 chr1:109817590 G/T cg20569855 chr1:109824440 PSRC1 -0.47 -6.1 -0.31 2.93e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs17666538 0.535 rs1669613 chr8:617565 G/C cg02524346 chr8:600233 NA 0.8 6.12 0.31 2.5e-9 IgG glycosylation; LIHC cis rs17685 0.593 rs56265719 chr7:75796269 C/T cg16684958 chr7:75615977 POR 0.39 6.42 0.33 4.61e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7937682 0.889 rs541198 chr11:111475340 A/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.96 -0.51 3.76e-24 Primary sclerosing cholangitis; LIHC cis rs2463822 1.000 rs2463825 chr11:62094493 G/A cg06239285 chr11:62104954 ASRGL1 0.93 7.14 0.36 5.5e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2777491 1.000 rs7177641 chr15:41743426 C/T cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.28 -0.45 2.04e-18 Ulcerative colitis; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg16528022 chr14:65438707 RAB15 0.46 6.1 0.31 2.87e-9 Hepatitis; LIHC cis rs853679 0.517 rs9357061 chr6:28051772 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg09323728 chr8:95962352 TP53INP1 -0.3 -6.42 -0.33 4.5e-10 Type 2 diabetes; LIHC cis rs11098499 0.535 rs10005542 chr4:120268302 T/C cg09307838 chr4:120376055 NA 0.63 9.88 0.47 2.07e-20 Corneal astigmatism; LIHC cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg10295955 chr4:187884368 NA -0.96 -22.7 -0.78 3.2e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs68092024 0.731 rs793479 chr3:99488232 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.91 0.3 8.09e-9 Cleft lip with or without cleft palate; LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC trans rs73186030 1.000 rs55838400 chr3:122032293 T/C cg13973942 chr17:977984 ABR 0.47 6.06 0.31 3.6e-9 Serum parathyroid hormone levels; LIHC trans rs561341 1.000 rs501312 chr17:30329066 A/G cg20587970 chr11:113659929 NA -1.41 -12.24 -0.55 7.93e-29 Hip circumference adjusted for BMI; LIHC cis rs8062405 0.728 rs8056890 chr16:28897452 G/A cg00204512 chr16:28754710 NA 0.34 6.1 0.31 2.79e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1555322 0.530 rs932562 chr20:33871310 T/C cg07134254 chr20:33865797 NA 0.53 6.26 0.32 1.13e-9 Attention deficit hyperactivity disorder; LIHC cis rs796364 1.000 rs4410273 chr2:200818258 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.8 9.6 0.46 1.7e-19 Schizophrenia; LIHC cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC cis rs6596100 0.538 rs59682592 chr5:132196800 C/T cg02081065 chr5:132209139 LEAP2 0.29 6.3 0.32 9.39e-10 Breast cancer; LIHC cis rs9378688 0.654 rs2479004 chr6:2326765 A/G cg12303981 chr6:2244766 GMDS -0.45 -6.11 -0.31 2.69e-9 Caudate nucleus volume; LIHC cis rs881375 0.933 rs7028641 chr9:123691141 G/C cg14580859 chr9:123691850 NA 0.39 6.85 0.35 3.54e-11 Rheumatoid arthritis; LIHC cis rs12477438 0.520 rs13030961 chr2:99799520 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.16 0.63 4.65e-40 Chronic sinus infection; LIHC cis rs2806561 0.769 rs2235547 chr1:23406485 C/G cg19743168 chr1:23544995 NA -0.4 -7.4 -0.37 1.04e-12 Height; LIHC cis rs4423214 0.959 rs11606611 chr11:71164046 C/G cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg12310025 chr6:25882481 NA -0.52 -6.31 -0.32 8.48e-10 Intelligence (multi-trait analysis); LIHC trans rs7849581 1 rs7849581 chr9:9924724 A/G cg17933722 chr1:116711077 NA 0.6 6.56 0.33 1.95e-10 Myopia (pathological); LIHC cis rs7572733 0.534 rs700692 chr2:198728500 T/C cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs17106184 1.000 rs72904732 chr1:51342809 A/G cg07174182 chr1:51127561 FAF1 -0.62 -6.46 -0.33 3.52e-10 Type 2 diabetes; LIHC cis rs35110281 0.811 rs4819264 chr21:45017349 G/T cg04455712 chr21:45112962 RRP1B 0.47 7.95 0.4 2.71e-14 Mean corpuscular volume; LIHC cis rs4713118 0.866 rs9468217 chr6:27726467 G/A cg20933634 chr6:27740509 NA 0.49 6.4 0.33 5.26e-10 Parkinson's disease; LIHC cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg27170947 chr2:26402098 FAM59B 0.71 8.5 0.42 5.87e-16 Gut microbiome composition (summer); LIHC cis rs6951245 1.000 rs11763020 chr7:1060288 C/T cg24642844 chr7:1081250 C7orf50 -0.88 -8.8 -0.43 6.97e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs722599 0.501 rs2286912 chr14:75385437 C/T cg08847533 chr14:75593920 NEK9 -0.6 -10.25 -0.48 1.16e-21 IgG glycosylation; LIHC cis rs7756236 0.521 rs9394368 chr6:36630525 C/G cg08179530 chr6:36648295 CDKN1A -0.57 -8.68 -0.42 1.64e-16 QRS duration; LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg08677398 chr8:58056175 NA 0.41 6.47 0.33 3.34e-10 Developmental language disorder (linguistic errors); LIHC trans rs9929218 0.954 rs2059254 chr16:68817439 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.66 -9.51 -0.46 3.48e-19 Colorectal cancer; LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg11618577 chr2:27665543 KRTCAP3 -0.44 -5.97 -0.31 5.81e-9 Total body bone mineral density; LIHC cis rs6502050 0.799 rs4789673 chr17:80123218 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs17270561 1.000 rs12200962 chr6:25828986 T/C cg17691542 chr6:26056736 HIST1H1C 0.71 7.98 0.4 2.23e-14 Iron status biomarkers; LIHC cis rs9768139 0.683 rs4909178 chr7:158117752 T/A cg25566285 chr7:158114605 PTPRN2 0.22 6.07 0.31 3.47e-9 Calcium levels; LIHC cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg18357526 chr6:26021779 HIST1H4A -1.06 -16.0 -0.65 2.14e-43 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.934 rs12630641 chr3:47534836 G/T cg27129171 chr3:47204927 SETD2 0.58 9.96 0.47 1.12e-20 Colorectal cancer; LIHC cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg23758822 chr17:41437982 NA 0.94 17.78 0.69 1.48e-50 Menopause (age at onset); LIHC cis rs8180040 0.620 rs4683322 chr3:47093189 T/C cg27129171 chr3:47204927 SETD2 0.56 9.23 0.45 2.84e-18 Colorectal cancer; LIHC cis rs7572733 0.534 rs11899188 chr2:198740121 C/T cg03934865 chr2:198174659 NA 0.45 6.51 0.33 2.76e-10 Dermatomyositis; LIHC cis rs6547741 1.000 rs1080060 chr2:27768808 T/A cg27432699 chr2:27873401 GPN1 0.71 11.37 0.52 1.21e-25 Oral cavity cancer; LIHC cis rs2412488 0.888 rs10028142 chr4:54331867 A/G cg22241045 chr4:54363911 LNX1 -0.41 -6.65 -0.34 1.15e-10 DNA methylation (variation); LIHC cis rs6448317 0.597 rs3843416 chr4:24903822 T/C cg21108841 chr4:24914750 CCDC149 0.52 6.39 0.33 5.45e-10 Heschl's gyrus morphology; LIHC cis rs2832191 0.636 rs8131283 chr21:30516796 A/G cg08807101 chr21:30365312 RNF160 -0.44 -6.29 -0.32 9.94e-10 Dental caries; LIHC cis rs2153535 0.580 rs4639392 chr6:8446547 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs11779988 0.516 rs426498 chr8:17897158 T/C cg01800426 chr8:17659068 MTUS1 -0.44 -7.0 -0.35 1.34e-11 Breast cancer; LIHC cis rs507080 0.922 rs478371 chr11:118565336 G/A cg04173919 chr11:118528438 PHLDB1 0.36 6.63 0.34 1.3e-10 Serum metabolite levels; LIHC cis rs11711311 1.000 rs62268169 chr3:113493860 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.81 -0.35 4.44e-11 IgG glycosylation; LIHC cis rs6424115 1.000 rs7515969 chr1:24158398 G/A cg15997130 chr1:24165203 NA -0.45 -9.01 -0.44 1.51e-17 Immature fraction of reticulocytes; LIHC cis rs9549367 0.826 rs2287249 chr13:113889355 A/G cg00898013 chr13:113819073 PROZ -0.43 -7.52 -0.38 5e-13 Platelet distribution width; LIHC cis rs6596100 0.538 rs67504728 chr5:132194045 G/A cg02081065 chr5:132209139 LEAP2 0.29 6.3 0.32 9.39e-10 Breast cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08522065 chr12:46384600 SFRS2IP -0.44 -6.27 -0.32 1.06e-9 Systolic blood pressure; LIHC cis rs7487075 0.578 rs1492895 chr12:46808755 C/T cg23829395 chr12:46796953 NA 0.35 6.26 0.32 1.16e-9 Itch intensity from mosquito bite; LIHC cis rs7635838 0.892 rs4684773 chr3:11418508 C/T cg00170343 chr3:11313890 ATG7 0.44 7.0 0.35 1.4e-11 HDL cholesterol; LIHC cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg03517284 chr6:25882590 NA -0.64 -9.12 -0.44 6.56e-18 Blood metabolite levels; LIHC cis rs28830936 1.000 rs4923905 chr15:41909889 G/A cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.06 -0.31 3.64e-9 Diastolic blood pressure; LIHC cis rs6748734 1.000 rs4344931 chr2:241818527 A/C cg04034577 chr2:241836375 C2orf54 -0.38 -7.49 -0.38 5.95e-13 Urinary metabolites; LIHC cis rs72990858 0.687 rs62418773 chr6:105173120 A/G cg02098413 chr6:105308735 HACE1 -0.38 -5.75 -0.3 1.97e-8 Sporadic neuroblastoma; LIHC cis rs6502050 0.835 rs8077926 chr17:80117315 C/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 1e-8 Life satisfaction; LIHC cis rs7772486 0.875 rs9322045 chr6:146384950 C/G cg23711669 chr6:146136114 FBXO30 0.59 10.53 0.49 1.23e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg05665937 chr4:1216051 CTBP1 0.47 6.37 0.33 6.06e-10 Obesity-related traits; LIHC trans rs2235573 0.527 rs139878 chr22:38361559 C/T cg19894588 chr14:64061835 NA 0.47 6.14 0.32 2.34e-9 Glioblastoma;Glioma; LIHC cis rs9348729 1 rs9348729 chr6:26664268 T/C cg12826209 chr6:26865740 GUSBL1 0.55 5.8 0.3 1.48e-8 Intelligence (multi-trait analysis); LIHC cis rs8141529 0.644 rs5752795 chr22:29178820 T/C cg15103426 chr22:29168792 CCDC117 0.67 11.68 0.53 9.46e-27 Lymphocyte counts; LIHC cis rs8103278 0.662 rs16980051 chr19:46345886 T/C cg11657440 chr19:46296263 DMWD -0.44 -7.14 -0.36 5.77e-12 Coronary artery disease; LIHC cis rs9517320 0.534 rs4771306 chr13:99143661 T/C cg07423050 chr13:99094983 FARP1 -0.49 -8.89 -0.43 3.55e-17 Longevity; LIHC cis rs11229555 0.645 rs12291551 chr11:58176915 T/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1552244 0.572 rs68013239 chr3:10165711 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs7772486 0.641 rs9390370 chr6:146357569 C/T cg13319975 chr6:146136371 FBXO30 -0.53 -8.41 -0.41 1.15e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs4474465 0.833 rs10899540 chr11:78245549 T/A cg27205649 chr11:78285834 NARS2 0.41 6.52 0.33 2.49e-10 Alzheimer's disease (survival time); LIHC cis rs2153535 0.580 rs9378556 chr6:8514695 A/G cg21535247 chr6:8435926 SLC35B3 0.63 8.29 0.41 2.68e-15 Motion sickness; LIHC cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg02290350 chr8:58132656 NA 0.51 9.6 0.46 1.75e-19 Developmental language disorder (linguistic errors); LIHC cis rs7582180 0.629 rs11686880 chr2:100956229 C/T cg14675211 chr2:100938903 LONRF2 0.54 8.58 0.42 3.3e-16 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC trans rs7618501 1.000 rs6785549 chr3:49736565 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.8 -14.7 -0.62 2.98e-38 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.953 rs10904583 chr10:983498 T/C cg26597838 chr10:835615 NA 0.95 11.15 0.52 7.63e-25 Eosinophil percentage of granulocytes; LIHC cis rs6584283 0.846 rs7917446 chr10:101286207 T/C cg06854084 chr10:101292507 NKX2-3 -0.32 -5.92 -0.3 7.91e-9 Ulcerative colitis; LIHC cis rs7937890 0.967 rs963212 chr11:14324732 A/G cg23387056 chr11:14280742 SPON1 0.43 5.99 0.31 5.25e-9 Mitochondrial DNA levels; LIHC trans rs9929218 1.000 rs13339591 chr16:68809273 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs763014 0.966 rs4984904 chr16:680809 C/G cg09263875 chr16:632152 PIGQ 0.6 10.33 0.49 5.86e-22 Height; LIHC cis rs2933343 0.859 rs789247 chr3:128580585 C/A cg25356066 chr3:128598488 ACAD9 0.55 7.36 0.37 1.4e-12 IgG glycosylation; LIHC cis rs904251 1.000 rs904251 chr6:37451696 G/T cg01843034 chr6:37503916 NA -0.4 -6.58 -0.34 1.8e-10 Cognitive performance; LIHC cis rs6545883 0.825 rs7578139 chr2:61564121 G/A cg14146966 chr2:61757674 XPO1 -0.44 -7.44 -0.37 7.95e-13 Tuberculosis; LIHC cis rs950169 0.656 rs748455 chr15:85149575 T/C cg17507749 chr15:85114479 UBE2QP1 0.7 7.79 0.39 7.88e-14 Schizophrenia; LIHC cis rs17539620 0.519 rs4077066 chr6:154838448 C/G cg17771515 chr6:154831774 CNKSR3 0.54 6.02 0.31 4.46e-9 Lipoprotein (a) levels; LIHC cis rs7772486 0.790 rs9485024 chr6:146142487 A/G cg23711669 chr6:146136114 FBXO30 -0.62 -10.54 -0.5 1.12e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs10089 1.000 rs10478803 chr5:127488855 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.61 0.34 1.45e-10 Ileal carcinoids; LIHC cis rs1144333 0.655 rs7418941 chr1:76436020 A/G cg10523679 chr1:76189770 ACADM 0.46 6.28 0.32 1.05e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs4474465 0.646 rs7927503 chr11:78280606 G/T cg02023728 chr11:77925099 USP35 -0.33 -5.96 -0.31 6.23e-9 Alzheimer's disease (survival time); LIHC cis rs1865760 0.963 rs3846838 chr6:25911775 T/C cg17691542 chr6:26056736 HIST1H1C 0.41 6.09 0.31 3.04e-9 Height; LIHC cis rs372883 0.600 rs2832294 chr21:30739671 A/C cg24692254 chr21:30365293 RNF160 0.5 6.26 0.32 1.18e-9 Pancreatic cancer; LIHC cis rs6586163 0.843 rs1926199 chr10:90746660 G/T cg03111039 chr10:90751583 FAS;ACTA2 -0.54 -7.82 -0.39 6.64e-14 Chronic lymphocytic leukemia; LIHC trans rs11098499 0.754 rs4107728 chr4:120253910 G/A cg25214090 chr10:38739885 LOC399744 0.52 8.45 0.42 8.33e-16 Corneal astigmatism; LIHC cis rs55665837 1.000 rs10832278 chr11:14496619 G/A cg19336497 chr11:14380999 RRAS2 -0.45 -8.08 -0.4 1.1e-14 Vitamin D levels; LIHC cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg11645453 chr3:52864694 ITIH4 0.21 5.8 0.3 1.48e-8 Bipolar disorder; LIHC cis rs6570726 0.791 rs1280275 chr6:145892402 C/T cg23711669 chr6:146136114 FBXO30 0.72 12.85 0.57 4.31e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg06634786 chr22:41940651 POLR3H 0.82 9.29 0.45 1.88e-18 Vitiligo; LIHC cis rs7945705 0.747 rs2653605 chr11:8993309 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.4 -6.59 -0.34 1.65e-10 Hemoglobin concentration; LIHC cis rs10751667 0.643 rs7396407 chr11:929374 A/T cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg03721293 chr16:90014378 DEF8 0.42 7.1 0.36 7.25e-12 Skin colour saturation; LIHC cis rs11122272 0.706 rs2749710 chr1:231535112 A/C cg06096015 chr1:231504339 EGLN1 -0.52 -9.69 -0.46 8.84e-20 Hemoglobin concentration; LIHC trans rs3176789 0.671 rs10772128 chr12:9921868 G/A cg18988856 chr7:99425577 CYP3A43 0.19 6.13 0.31 2.46e-9 Lymphocyte percentage of white cells;Neutrophil percentage of white cells; LIHC cis rs1129187 0.748 rs6458312 chr6:42904274 G/T cg02359409 chr6:42947317 PEX6 -0.45 -6.66 -0.34 1.11e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7216064 1.000 rs62084248 chr17:65874541 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg11645453 chr3:52864694 ITIH4 0.22 6.04 0.31 3.96e-9 Bipolar disorder; LIHC cis rs1816752 0.935 rs3816219 chr13:25017133 C/T cg22771759 chr13:24902376 NA 0.31 6.44 0.33 3.98e-10 Obesity-related traits; LIHC cis rs6952808 0.707 rs13244345 chr7:1973004 A/G cg21782813 chr7:2030301 MAD1L1 0.45 7.72 0.39 1.34e-13 Bipolar disorder and schizophrenia; LIHC cis rs11711311 1.000 rs12637067 chr3:113527606 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.01 0.44 1.5e-17 IgG glycosylation; LIHC cis rs57590327 0.504 rs11712243 chr3:81840674 T/G cg07356753 chr3:81810745 GBE1 -0.56 -8.63 -0.42 2.33e-16 Extraversion; LIHC cis rs9916302 0.706 rs439537 chr17:37734482 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -12.02 -0.54 5.34e-28 Glomerular filtration rate (creatinine); LIHC cis rs2075371 0.863 rs1646635 chr7:134006728 T/C cg20476274 chr7:133979776 SLC35B4 0.71 12.1 0.55 2.66e-28 Mean platelet volume; LIHC cis rs796364 0.616 rs2030653 chr2:200677625 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.15 0.32 2.21e-9 Schizophrenia; LIHC cis rs4474465 1.000 rs7943673 chr11:78172986 A/G cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs778371 0.874 rs1083522 chr2:233745521 C/T cg08000102 chr2:233561755 GIGYF2 -0.84 -13.42 -0.59 2.77e-33 Schizophrenia; LIHC cis rs2439831 0.850 rs28509275 chr15:44098105 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.59 6.85 0.35 3.49e-11 Lung cancer in ever smokers; LIHC cis rs11098499 0.697 rs10020027 chr4:120381879 G/C cg09307838 chr4:120376055 NA 0.79 12.54 0.56 5.98e-30 Corneal astigmatism; LIHC cis rs35160687 0.644 rs9309635 chr2:86499402 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.36 -5.91 -0.3 8.09e-9 Night sleep phenotypes; LIHC cis rs921968 0.643 rs612874 chr2:219492924 T/C cg17980119 chr2:219472607 PLCD4 0.34 5.71 0.3 2.4e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg04013166 chr16:89971882 TCF25 0.59 7.84 0.39 5.79e-14 Skin colour saturation; LIHC cis rs422249 0.634 rs174614 chr11:61628915 T/C cg27386326 chr11:61587980 NA 0.33 5.78 0.3 1.67e-8 Trans fatty acid levels; LIHC cis rs992157 0.698 rs6746089 chr2:219170377 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.77 12.29 0.55 5.32e-29 Colorectal cancer; LIHC cis rs12497850 0.764 rs6784111 chr3:49178846 T/C cg06212747 chr3:49208901 KLHDC8B 0.6 7.83 0.39 6.06e-14 Parkinson's disease; LIHC cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg18230493 chr5:56204884 C5orf35 -0.47 -6.55 -0.33 2.08e-10 Initial pursuit acceleration; LIHC cis rs9814567 1.000 rs6790466 chr3:134197740 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.73 -0.3 2.2e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs62103177 0.733 rs62103193 chr18:77629217 C/T cg05926928 chr17:57297772 GDPD1 1.1 11.26 0.52 3.23e-25 Opioid sensitivity; LIHC cis rs9303280 0.836 rs12453507 chr17:38053207 C/G cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.71 0.3 2.43e-8 Self-reported allergy; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC trans rs867371 1.000 rs1846911 chr15:82468650 G/A cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.11 -0.36 7.02e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg08280861 chr8:58055591 NA -0.49 -6.2 -0.32 1.59e-9 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.579 rs2504140 chr10:38387579 T/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs858239 0.539 rs6956828 chr7:23187347 A/G cg23682824 chr7:23144976 KLHL7 0.43 6.47 0.33 3.41e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs9549367 0.789 rs2316442 chr13:113877487 C/T cg18105134 chr13:113819100 PROZ -0.68 -11.63 -0.53 1.48e-26 Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14407075 chr12:50794574 LARP4 0.5 6.61 0.34 1.45e-10 Lung function (FEV1/FVC); LIHC cis rs8180040 0.966 rs6765990 chr3:47542894 G/A cg16586182 chr3:47516702 SCAP -0.58 -11.26 -0.52 3.21e-25 Colorectal cancer; LIHC cis rs7617773 0.746 rs11713476 chr3:48375434 C/T cg11946769 chr3:48343235 NME6 0.72 9.52 0.46 3.3e-19 Coronary artery disease; LIHC cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.63 -0.38 2.34e-13 Bipolar disorder; LIHC cis rs3806843 0.778 rs2531346 chr5:140126139 T/G cg19875535 chr5:140030758 IK -0.36 -5.99 -0.31 5.21e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1000083 0.915 rs1000082 chr5:96533260 A/G ch.5.96698337R chr5:96672581 NA 0.87 6.94 0.35 1.96e-11 Cisplatin-induced ototoxicity; LIHC cis rs4824093 0.610 rs58671506 chr22:50288983 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.73 -5.76 -0.3 1.83e-8 Amyotrophic lateral sclerosis (sporadic); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05572930 chr6:125404126 RNF217 0.3 6.25 0.32 1.26e-9 Pancreatic cancer; LIHC cis rs2153535 0.505 rs9405395 chr6:8468622 T/A cg21535247 chr6:8435926 SLC35B3 0.6 7.8 0.39 7.36e-14 Motion sickness; LIHC cis rs1043515 1.000 rs1043515 chr17:36922196 C/T cg09592244 chr17:37024020 NA -0.41 -6.68 -0.34 9.49e-11 Height; LIHC cis rs2235642 0.671 rs2235641 chr16:1608177 A/G cg03034668 chr16:1723424 CRAMP1L -0.43 -7.24 -0.36 2.99e-12 Coronary artery disease; LIHC cis rs941873 0.868 rs4980063 chr10:81105844 A/T cg11057378 chr10:81107060 PPIF 0.36 6.01 0.31 4.64e-9 Height; LIHC cis rs67460515 0.563 rs68166680 chr3:160829735 T/A cg03342759 chr3:160939853 NMD3 -0.61 -9.06 -0.44 1.02e-17 Parkinson's disease; LIHC cis rs9911578 1.000 rs2531729 chr17:56539890 C/T cg12560992 chr17:57184187 TRIM37 0.96 17.27 0.68 1.68e-48 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg18404041 chr3:52824283 ITIH1 -0.58 -9.65 -0.46 1.16e-19 Electroencephalogram traits; LIHC cis rs79518236 1 rs79518236 chr7:98026554 ACT/A cg09267113 chr7:98030324 BAIAP2L1 -0.56 -9.78 -0.47 4.53e-20 Breast cancer; LIHC cis rs963731 0.522 rs1454222 chr2:39215895 C/A cg04010122 chr2:39346883 SOS1 -0.69 -6.03 -0.31 4.14e-9 Corticobasal degeneration; LIHC cis rs67311347 0.910 rs7617361 chr3:40373259 G/T cg00656387 chr3:40428638 ENTPD3 0.41 6.77 0.34 5.72e-11 Renal cell carcinoma; LIHC cis rs6089584 0.566 rs2146852 chr20:60616492 T/G cg06108461 chr20:60628389 TAF4 -0.65 -9.17 -0.44 4.59e-18 Body mass index; LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.69 0.57 1.67e-30 Prudent dietary pattern; LIHC cis rs360798 0.512 rs2539978 chr2:63195179 T/C cg17519650 chr2:63277830 OTX1 0.46 7.12 0.36 6.39e-12 Coronary artery disease; LIHC cis rs7223966 1.000 rs11657306 chr17:61704822 G/A cg05941027 chr17:61774174 LIMD2 0.32 6.54 0.33 2.25e-10 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs526821 0.553 rs519637 chr11:55295935 A/T cg03929089 chr4:120376271 NA -0.46 -7.02 -0.35 1.21e-11 Pediatric bone mineral density (spine); LIHC cis rs2180341 0.960 rs9398839 chr6:127665863 G/A cg24812749 chr6:127587940 RNF146 1.05 15.38 0.64 6.23e-41 Breast cancer; LIHC cis rs7818688 0.697 rs74633235 chr8:95981476 A/G cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg04627240 chr19:42746847 GSK3A -0.42 -6.45 -0.33 3.92e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11676348 0.818 rs1126579 chr2:219000734 T/C cg00012203 chr2:219082015 ARPC2 -0.55 -7.67 -0.38 1.81e-13 Ulcerative colitis; LIHC cis rs6461049 0.765 rs10224497 chr7:2149967 A/G cg22963979 chr7:1858916 MAD1L1 -0.37 -5.94 -0.31 6.93e-9 Schizophrenia; LIHC cis rs2404602 0.716 rs56351018 chr15:76824591 T/C cg23625390 chr15:77176239 SCAPER 0.37 5.97 0.31 5.97e-9 Blood metabolite levels; LIHC cis rs12048904 0.512 rs932798 chr1:101249355 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.6 -9.49 -0.46 4.02e-19 Multiple sclerosis; LIHC cis rs2760061 0.819 rs708114 chr1:228197496 G/A cg01200585 chr1:228362443 C1orf69 0.4 6.08 0.31 3.13e-9 Diastolic blood pressure; LIHC cis rs796364 0.806 rs11691873 chr2:200966337 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.75 -8.36 -0.41 1.57e-15 Schizophrenia; LIHC cis rs2836950 0.565 rs7279497 chr21:40531306 A/G cg11890956 chr21:40555474 PSMG1 0.44 7.35 0.37 1.45e-12 Menarche (age at onset); LIHC trans rs12310956 0.515 rs1830086 chr12:33958874 C/T cg26384229 chr12:38710491 ALG10B 0.53 7.28 0.37 2.27e-12 Morning vs. evening chronotype; LIHC cis rs1552244 0.882 rs13089863 chr3:10032259 G/T cg13047869 chr3:10149882 C3orf24 -0.44 -5.89 -0.3 9.06e-9 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11555122 chr17:5095235 ZNF594 -0.41 -6.05 -0.31 3.88e-9 Cognitive function; LIHC cis rs56235845 0.694 rs36102285 chr5:176774018 C/T cg17509989 chr5:176798049 RGS14 0.63 8.43 0.41 9.770000000000001e-16 Hemoglobin concentration;Hematocrit; LIHC cis rs12701220 0.690 rs10243973 chr7:1064983 T/C cg04025307 chr7:1156635 C7orf50 0.46 6.05 0.31 3.75e-9 Bronchopulmonary dysplasia; LIHC cis rs35883536 1.000 rs2282253 chr1:101094383 C/G cg14515779 chr1:101123966 NA -0.67 -13.12 -0.58 3.87e-32 Monocyte count; LIHC cis rs6089584 1.000 rs6089591 chr20:60570548 A/C cg06108461 chr20:60628389 TAF4 -0.87 -13.74 -0.6 1.58e-34 Body mass index; LIHC cis rs6951245 1.000 rs79443843 chr7:1075245 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.12 0.31 2.49e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs60871478 0.947 rs62432866 chr7:809281 T/G cg04727924 chr7:799746 HEATR2 -0.59 -8.71 -0.43 1.34e-16 Cerebrospinal P-tau181p levels; LIHC cis rs6121246 0.567 rs6060295 chr20:30198473 C/T cg13852791 chr20:30311386 BCL2L1 0.76 6.82 0.35 4.02e-11 Mean corpuscular hemoglobin; LIHC cis rs9916302 0.605 rs2879258 chr17:37399379 G/T cg07936489 chr17:37558343 FBXL20 -0.82 -11.28 -0.52 2.75e-25 Glomerular filtration rate (creatinine); LIHC cis rs6952808 0.572 rs1860826 chr7:2112506 G/A cg04267008 chr7:1944627 MAD1L1 -0.53 -7.92 -0.39 3.46e-14 Bipolar disorder and schizophrenia; LIHC cis rs831571 0.636 rs831565 chr3:64076358 G/A cg16258503 chr3:63850278 ATXN7;THOC7 0.53 6.76 0.34 5.93e-11 Type 2 diabetes; LIHC cis rs6840360 1.000 rs6834095 chr4:152603278 C/T cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.19e-10 Intelligence (multi-trait analysis); LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg21756720 chr8:11724777 CTSB -0.65 -6.65 -0.34 1.13e-10 Obesity-related traits; LIHC cis rs801193 0.548 rs2109297 chr7:66122384 G/A cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs2180341 0.920 rs6906717 chr6:127596782 C/A cg24812749 chr6:127587940 RNF146 1.05 15.71 0.65 2.87e-42 Breast cancer; LIHC cis rs908922 0.676 rs4240884 chr1:152529792 C/T cg20991723 chr1:152506922 NA -0.53 -9.16 -0.44 4.82e-18 Hair morphology; LIHC cis rs1843834 0.539 rs6749402 chr2:225443901 T/G cg22509189 chr2:225307070 NA -0.83 -11.73 -0.54 6.42e-27 IgE levels in asthmatics (D.p. specific); LIHC cis rs1494373 0.543 rs12410279 chr1:220851520 A/G cg06786860 chr1:220876396 NA -0.41 -6.1 -0.31 2.84e-9 Response to antipsychotic therapy (extrapyramidal side effects); LIHC cis rs9583531 0.689 rs4773244 chr13:111383937 A/T cg24331049 chr13:111365604 ING1 -0.78 -13.09 -0.58 5.12e-32 Coronary artery disease; LIHC cis rs1552244 0.882 rs13066757 chr3:10045030 C/A cg08888203 chr3:10149979 C3orf24 0.49 6.13 0.31 2.48e-9 Alzheimer's disease; LIHC cis rs6840360 0.550 rs12651635 chr4:152557786 C/T cg22705602 chr4:152727874 NA -0.32 -6.2 -0.32 1.67e-9 Intelligence (multi-trait analysis); LIHC cis rs4721295 0.546 rs1637766 chr7:2204400 G/A cg02951883 chr7:2050386 MAD1L1 0.64 9.95 0.47 1.18e-20 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg03806693 chr22:41940476 POLR3H -1.12 -13.54 -0.59 9.53e-34 Vitiligo; LIHC cis rs36051895 0.623 rs3780382 chr9:5232299 G/A cg02405213 chr9:5042618 JAK2 -0.69 -11.21 -0.52 4.63e-25 Pediatric autoimmune diseases; LIHC cis rs4144743 1.000 rs4144744 chr17:45323262 A/G cg18085866 chr17:45331354 ITGB3 -0.59 -8.57 -0.42 3.74e-16 Body mass index; LIHC cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg20295408 chr7:1910781 MAD1L1 -0.43 -6.28 -0.32 1.02e-9 Schizophrenia; LIHC cis rs7584330 0.554 rs880931 chr2:238396741 G/A cg08992911 chr2:238395768 MLPH 0.62 6.78 0.34 5.28e-11 Prostate cancer; LIHC cis rs7945705 0.747 rs2742480 chr11:8993130 A/G cg12365402 chr11:9010492 NRIP3 -0.34 -8.82 -0.43 5.92e-17 Hemoglobin concentration; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs17001868 0.568 rs73167007 chr22:40734241 G/C cg07138101 chr22:40742427 ADSL 0.54 6.27 0.32 1.11e-9 Mammographic density (dense area); LIHC cis rs4862307 0.720 rs12650935 chr4:184989565 G/A cg22054328 chr4:184930219 STOX2 0.35 5.95 0.31 6.78e-9 Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs6089584 0.962 rs6142913 chr20:60566950 A/G cg06108461 chr20:60628389 TAF4 -0.96 -15.77 -0.65 1.67e-42 Body mass index; LIHC cis rs6840360 0.571 rs4696272 chr4:152528229 A/G cg22705602 chr4:152727874 NA -0.32 -6.38 -0.33 5.62e-10 Intelligence (multi-trait analysis); LIHC cis rs4820294 0.516 rs12484441 chr22:38097359 C/G cg00292662 chr22:38071168 LGALS1 0.64 8.48 0.42 6.74e-16 Fat distribution (HIV); LIHC cis rs3806843 0.832 rs2531360 chr5:140116664 G/A cg26395211 chr5:140044315 WDR55 0.39 5.72 0.3 2.29e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7089973 0.585 rs7907837 chr10:116610690 G/T cg23260525 chr10:116636907 FAM160B1 0.38 7.54 0.38 4.13e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg21644426 chr2:191273491 MFSD6 0.54 7.55 0.38 3.98e-13 Pulse pressure; LIHC cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg02475777 chr4:1388615 CRIPAK 0.53 8.07 0.4 1.24e-14 Longevity; LIHC cis rs7131987 0.650 rs11050208 chr12:29510369 T/G cg00204748 chr12:29376779 FAR2 0.38 6.72 0.34 7.47e-11 QT interval; LIHC cis rs8016982 0.674 rs61980899 chr14:81676844 T/C cg01989461 chr14:81687754 GTF2A1 0.7 14.28 0.61 1.26e-36 Schizophrenia; LIHC cis rs36051895 0.664 rs10116560 chr9:5096433 A/G cg02405213 chr9:5042618 JAK2 -0.67 -11.1 -0.51 1.14e-24 Pediatric autoimmune diseases; LIHC trans rs7615952 0.546 rs2976733 chr3:125414138 T/C cg07211511 chr3:129823064 LOC729375 -0.45 -6.14 -0.32 2.31e-9 Blood pressure (smoking interaction); LIHC cis rs2404602 0.716 rs4079681 chr15:76695230 G/A cg23625390 chr15:77176239 SCAPER 0.37 6.13 0.31 2.47e-9 Blood metabolite levels; LIHC cis rs17401966 0.522 rs10864450 chr1:10333959 G/T cg19773385 chr1:10388646 KIF1B -0.34 -6.03 -0.31 4.33e-9 Hepatocellular carcinoma; LIHC cis rs1728785 1.000 rs1645923 chr16:68581051 G/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs6960043 0.875 rs17168594 chr7:15048776 T/C cg19272540 chr7:15055459 NA -0.22 -6.13 -0.31 2.48e-9 Type 2 diabetes; LIHC cis rs5769707 0.521 rs5769719 chr22:50062101 G/A cg07959070 chr22:50026188 C22orf34 -0.3 -7.19 -0.36 4.03e-12 Monocyte count;Monocyte percentage of white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18804080 chr3:25705791 TOP2B -0.41 -6.35 -0.32 6.93e-10 Cognitive function; LIHC trans rs12478296 0.901 rs73007142 chr2:243010852 T/C cg01596870 chr19:55963115 NA -0.59 -6.83 -0.35 3.92e-11 Obesity-related traits; LIHC cis rs10791097 0.678 rs10894272 chr11:130731081 A/G cg12179176 chr11:130786555 SNX19 0.72 11.57 0.53 2.31e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2072499 0.932 rs2736613 chr1:156196016 T/C cg24450063 chr1:156163899 SLC25A44 1.02 17.38 0.68 6.31e-49 Testicular germ cell tumor; LIHC cis rs7572733 0.515 rs13382697 chr2:198920560 A/C cg03934865 chr2:198174659 NA 0.42 5.93 0.31 7.6e-9 Dermatomyositis; LIHC cis rs17152411 0.625 rs10901838 chr10:126623542 A/C cg07906193 chr10:126599966 NA -0.3 -5.77 -0.3 1.8e-8 Height; LIHC cis rs3020736 0.500 rs5996111 chr22:42493902 C/T cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.23 -0.32 1.39e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs66573146 0.572 rs66611116 chr4:6953270 A/G cg15105060 chr4:7024189 TBC1D14 -0.68 -6.1 -0.31 2.88e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6430585 0.583 rs3769001 chr2:136626078 A/G cg07169764 chr2:136633963 MCM6 1.34 22.33 0.77 8.99e-69 Corneal structure; LIHC cis rs1018836 0.851 rs7004287 chr8:91620842 G/C cg16814680 chr8:91681699 NA -0.61 -9.77 -0.47 4.66e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs783540 0.934 rs803747 chr15:83258096 A/G cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.63 -0.34 1.33e-10 Schizophrenia; LIHC cis rs875971 0.862 rs778720 chr7:65846275 A/C cg18876405 chr7:65276391 NA -0.35 -6.25 -0.32 1.2e-9 Aortic root size; LIHC cis rs3806843 0.868 rs2531345 chr5:140126781 T/G cg26395211 chr5:140044315 WDR55 0.39 5.79 0.3 1.61e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs4908768 0.906 rs11121182 chr1:8522553 G/T cg25722041 chr1:8623473 RERE 0.45 6.59 0.34 1.67e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs67460515 0.500 rs9832109 chr3:160723364 T/C cg17135325 chr3:160939158 NMD3 0.42 5.73 0.3 2.21e-8 Parkinson's disease; LIHC cis rs9457247 0.624 rs17524252 chr6:167466978 T/G cg07741184 chr6:167504864 NA 0.36 8.32 0.41 2.16e-15 Crohn's disease; LIHC cis rs7666738 0.830 rs62321565 chr4:98976571 G/A cg05340658 chr4:99064831 C4orf37 0.72 13.24 0.58 1.37e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs7937682 0.883 rs1784776 chr11:111472392 C/T cg22437258 chr11:111473054 SIK2 0.51 5.74 0.3 2.11e-8 Primary sclerosing cholangitis; LIHC cis rs7659604 0.628 rs3828485 chr4:122722368 G/A cg19748678 chr4:122722346 EXOSC9 0.67 11.04 0.51 1.93e-24 Type 2 diabetes; LIHC cis rs2303745 0.589 rs1965717 chr19:17398559 C/T cg10664184 chr19:17420304 DDA1 0.46 5.88 0.3 9.53e-9 Systemic lupus erythematosus; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01893041 chr5:67583972 PIK3R1 0.44 6.94 0.35 1.96e-11 Cognitive function; LIHC cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg06238570 chr21:40685208 BRWD1 0.6 7.25 0.37 2.79e-12 Cognitive function; LIHC cis rs10791097 0.547 rs10791101 chr11:130739133 C/T cg12179176 chr11:130786555 SNX19 0.83 13.71 0.6 2.07e-34 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1580019 0.563 rs10486509 chr7:32585443 C/G cg07520158 chr7:32535189 LSM5;AVL9 -0.59 -8.75 -0.43 9.62e-17 Cognitive ability; LIHC trans rs11098499 0.954 rs9998585 chr4:120396802 T/A cg25214090 chr10:38739885 LOC399744 0.58 9.59 0.46 1.9e-19 Corneal astigmatism; LIHC cis rs6964587 0.626 rs10266424 chr7:91503228 C/T cg17063962 chr7:91808500 NA -0.61 -11.1 -0.51 1.2e-24 Breast cancer; LIHC cis rs34779708 0.931 rs4934721 chr10:35377715 A/G cg03585969 chr10:35415529 CREM 0.85 12.94 0.57 1.85e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2204008 0.807 rs11182461 chr12:38539288 T/C cg26384229 chr12:38710491 ALG10B 0.95 12.37 0.56 2.58e-29 Bladder cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01428361 chr17:48556460 RSAD1 -0.43 -6.22 -0.32 1.47e-9 Cognitive function; LIHC cis rs11719291 0.833 rs11709246 chr3:48859498 G/A cg00383909 chr3:49044727 WDR6 0.96 7.95 0.4 2.65e-14 Cognitive function; LIHC cis rs1403694 0.655 rs3806688 chr3:186434819 T/C cg12454167 chr3:186435060 KNG1 0.38 8.97 0.44 2.01e-17 Blood protein levels; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg11618577 chr2:27665543 KRTCAP3 -0.45 -6.13 -0.31 2.42e-9 Total body bone mineral density; LIHC cis rs9549328 0.879 rs12428058 chr13:113636504 G/A cg08890338 chr13:113700818 MCF2L -0.34 -5.72 -0.3 2.38e-8 Systolic blood pressure; LIHC cis rs826838 1.000 rs6582619 chr12:38729904 A/G cg26384229 chr12:38710491 ALG10B 1.08 15.0 0.63 1.96e-39 Heart rate; LIHC cis rs11577318 0.853 rs7541333 chr1:26622889 C/T cg18121669 chr1:26560928 CCDC21 0.49 8.15 0.4 6.75e-15 Granulocyte percentage of myeloid white cells; LIHC cis rs34172651 0.917 rs6497760 chr16:24806535 G/A cg00339695 chr16:24857497 SLC5A11 0.55 8.25 0.41 3.44e-15 Intelligence (multi-trait analysis); LIHC cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.13 11.73 0.54 6.32e-27 Platelet count; LIHC cis rs2540917 0.728 rs243065 chr2:60622064 C/G cg00543073 chr2:60773386 BCL11A -0.33 -6.56 -0.33 2.02e-10 Mean corpuscular volume; LIHC cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg17747265 chr1:1875780 NA -0.45 -7.89 -0.39 4.21e-14 Body mass index; LIHC cis rs6442522 0.606 rs3773459 chr3:15495644 T/C cg16303742 chr3:15540471 COLQ 0.39 6.3 0.32 9.08e-10 Uric acid levels; LIHC cis rs6430585 0.528 rs75753154 chr2:136665711 T/C cg07305463 chr2:136567211 LCT -0.38 -6.02 -0.31 4.47e-9 Corneal structure; LIHC cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg13397359 chr6:42928475 GNMT 0.7 10.02 0.48 6.91e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7615952 0.576 rs12497295 chr3:125818650 G/A cg05084668 chr3:125655381 ALG1L -0.39 -5.96 -0.31 6.12e-9 Blood pressure (smoking interaction); LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.11 0.52 1.06e-24 Prudent dietary pattern; LIHC cis rs2439831 0.867 rs2447196 chr15:43893818 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.7 -10.03 -0.48 6.22e-21 Lung cancer in ever smokers; LIHC cis rs1983891 0.955 rs9381076 chr6:41517564 G/A cg20194872 chr6:41519635 FOXP4 0.41 6.52 0.33 2.48e-10 Prostate cancer; LIHC cis rs1552244 0.572 rs68013239 chr3:10165711 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs765787 0.530 rs4775831 chr15:45534722 A/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs8180040 0.654 rs62246451 chr3:47211632 C/T cg16586182 chr3:47516702 SCAP 0.48 8.45 0.42 8.71e-16 Colorectal cancer; LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg07725925 chr16:89976287 TCF25 -0.42 -6.07 -0.31 3.37e-9 Skin colour saturation; LIHC cis rs9308433 0.529 rs4655336 chr1:214499667 A/C cg06198575 chr1:214491504 SMYD2 0.55 5.82 0.3 1.35e-8 IgG glycosylation; LIHC cis rs7953508 0.506 rs2200160 chr12:93963873 C/T cg18151635 chr12:93972918 NA -0.51 -8.59 -0.42 3.06e-16 Pubertal anthropometrics; LIHC cis rs7945705 0.791 rs6484484 chr11:8817206 A/G cg12365402 chr11:9010492 NRIP3 0.23 5.82 0.3 1.33e-8 Hemoglobin concentration; LIHC cis rs798554 0.610 rs2644297 chr7:2858906 A/C cg13628971 chr7:2884303 GNA12 0.44 7.04 0.36 1.05e-11 Height; LIHC cis rs35110281 0.632 rs9306160 chr21:45107562 T/C cg01579765 chr21:45077557 HSF2BP -0.32 -5.82 -0.3 1.35e-8 Mean corpuscular volume; LIHC cis rs2204008 0.715 rs11525003 chr12:38332359 G/A cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.57e-15 Bladder cancer; LIHC cis rs2120019 1.000 rs2083731 chr15:75368538 A/C cg17294928 chr15:75287854 SCAMP5 -0.51 -7.92 -0.39 3.34e-14 Blood trace element (Zn levels); LIHC cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg22907277 chr7:1156413 C7orf50 0.82 7.04 0.36 1.06e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs868036 0.681 rs4776375 chr15:68085555 G/A cg24579218 chr15:68104479 NA -0.34 -5.94 -0.31 7.12e-9 Restless legs syndrome; LIHC cis rs9911578 1.000 rs12449365 chr17:56600660 C/G cg12560992 chr17:57184187 TRIM37 -0.97 -17.64 -0.69 5.52e-50 Intelligence (multi-trait analysis); LIHC cis rs74417235 0.684 rs7723610 chr5:154053349 A/C cg08893839 chr5:154027129 NA 0.49 7.0 0.35 1.37e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs17125944 0.686 rs2357946 chr14:53345266 G/C cg00686598 chr14:53173677 PSMC6 -0.79 -8.73 -0.43 1.17e-16 Alzheimer's disease (late onset); LIHC cis rs7614311 0.636 rs73130576 chr3:63890875 T/C cg22134162 chr3:63841271 THOC7 -0.53 -5.99 -0.31 5.26e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs17106184 1.000 rs17106184 chr1:50909985 A/G cg07174182 chr1:51127561 FAF1 0.59 6.77 0.34 5.7e-11 Type 2 diabetes; LIHC cis rs12644436 0.628 rs1540587 chr4:88805810 G/A cg06891869 chr4:88767617 MEPE 0.43 7.47 0.37 6.87e-13 HIV-1 viral setpoint; LIHC cis rs3540 0.512 rs3862434 chr15:91080387 C/T cg22089800 chr15:90895588 ZNF774 0.49 7.08 0.36 8.14e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs8005677 1.000 rs10148215 chr14:23382345 C/T cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs35146811 0.586 rs12705067 chr7:99594726 T/C cg22906224 chr7:99728672 NA 0.49 6.62 0.34 1.39e-10 Coronary artery disease; LIHC cis rs1862618 0.671 rs2591970 chr5:56232595 T/C cg12311346 chr5:56204834 C5orf35 0.47 6.29 0.32 9.6e-10 Initial pursuit acceleration; LIHC cis rs12594515 0.904 rs8032875 chr15:45998010 A/C cg01629716 chr15:45996671 NA 0.51 9.21 0.45 3.44e-18 Waist circumference;Weight; LIHC cis rs17253792 0.822 rs79873916 chr14:56172631 G/C cg01858014 chr14:56050164 KTN1 -0.7 -7.28 -0.37 2.26e-12 Putamen volume; LIHC cis rs10876993 0.890 rs774888 chr12:58036506 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.39 -0.33 5.51e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs2574704 0.961 rs2616557 chr3:11658291 G/A cg15876825 chr3:11651881 VGLL4 0.5 8.26 0.41 3.17e-15 Body mass index; LIHC cis rs782590 0.935 rs782606 chr2:55886602 T/C cg03859395 chr2:55845619 SMEK2 0.9 15.77 0.65 1.76e-42 Metabolic syndrome; LIHC cis rs12022452 0.591 rs16827359 chr1:41001438 C/G cg25568243 chr1:40974465 DEM1 -0.45 -5.93 -0.31 7.24e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1055129 0.516 rs7218498 chr17:73931847 C/G cg19302996 chr17:73780495 UNK -0.47 -6.71 -0.34 7.92e-11 White matter hyperintensity burden; LIHC cis rs2576037 0.501 rs8089938 chr18:44459497 C/T cg19077165 chr18:44547161 KATNAL2 -0.43 -6.46 -0.33 3.62e-10 Personality dimensions; LIHC cis rs10911363 0.549 rs2794619 chr1:183459670 G/A cg09173681 chr1:183549694 NCF2 0.55 9.59 0.46 1.86e-19 Systemic lupus erythematosus; LIHC trans rs17685 0.712 rs10952842 chr7:75780413 G/A cg19862616 chr7:65841803 NCRNA00174 0.78 14.69 0.62 3.25e-38 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg23758822 chr17:41437982 NA 0.94 17.62 0.69 6.53e-50 Menopause (age at onset); LIHC cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.58 0.5 7.82e-23 Platelet count; LIHC cis rs1843834 0.539 rs6713629 chr2:225410973 A/T cg22509189 chr2:225307070 NA -0.83 -11.78 -0.54 3.97e-27 IgE levels in asthmatics (D.p. specific); LIHC trans rs10506458 0.915 rs2013050 chr12:63394310 C/T cg22491629 chr6:157744540 C6orf35 -0.61 -11.04 -0.51 2e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs5769765 0.778 rs4574208 chr22:50256738 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC trans rs11157436 0.918 rs12437004 chr14:22617415 G/T cg13567813 chr19:50879636 NR1H2 0.42 6.17 0.32 1.93e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.39e-8 Menopause (age at onset); LIHC cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg20295408 chr7:1910781 MAD1L1 -0.44 -6.45 -0.33 3.78e-10 Bipolar disorder and schizophrenia; LIHC cis rs17152411 1.000 rs12571196 chr10:126597749 A/C cg07906193 chr10:126599966 NA 0.48 7.31 0.37 1.9e-12 Height; LIHC cis rs35110281 0.548 rs7276316 chr21:45029333 A/T cg04455712 chr21:45112962 RRP1B 0.46 7.75 0.39 1.07e-13 Mean corpuscular volume; LIHC cis rs10193935 0.901 rs13384323 chr2:42631346 C/T cg27598129 chr2:42591480 NA -0.7 -10.72 -0.5 2.59e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs72627509 0.857 rs56155140 chr4:57824451 G/A cg26694713 chr4:57773883 REST 0.69 9.66 0.46 1.12e-19 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg18252515 chr7:66147081 NA -1.25 -16.31 -0.66 1.18e-44 Diabetic kidney disease; LIHC cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg22029157 chr1:209979665 IRF6 0.47 7.74 0.39 1.11e-13 Cleft lip with or without cleft palate; LIHC cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg19318889 chr4:1322082 MAEA 0.42 5.77 0.3 1.81e-8 Obesity-related traits; LIHC cis rs9581857 0.556 rs1885991 chr13:28040470 G/A cg22138327 chr13:27999177 GTF3A 0.48 7.01 0.35 1.26e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs11690935 0.550 rs4280427 chr2:172813218 G/A cg13550731 chr2:172543902 DYNC1I2 0.42 6.1 0.31 2.81e-9 Schizophrenia; LIHC cis rs9309711 0.689 rs4535075 chr2:3481716 T/C cg15506890 chr2:3487001 NA -0.47 -7.55 -0.38 4.12e-13 Neurofibrillary tangles; LIHC cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.36 0.45 1.06e-18 Bipolar disorder; LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg22903471 chr2:27725779 GCKR -0.48 -8.39 -0.41 1.28e-15 Total body bone mineral density; LIHC cis rs10870270 0.913 rs115236491 chr10:133766855 T/G cg08754478 chr10:133766260 PPP2R2D -0.55 -8.09 -0.4 1.03e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7592578 0.679 rs62181019 chr2:191325414 A/G cg27211696 chr2:191398769 TMEM194B -0.52 -6.92 -0.35 2.17e-11 Diastolic blood pressure; LIHC cis rs7551222 0.752 rs10900593 chr1:204470096 G/T cg20240347 chr1:204465584 NA -0.33 -7.0 -0.35 1.36e-11 Schizophrenia; LIHC cis rs7715806 0.500 rs10515213 chr5:74980572 C/T cg19683494 chr5:74908142 NA -0.69 -7.93 -0.39 3.15e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9611519 0.780 rs9611542 chr22:41677317 C/T cg03806693 chr22:41940476 POLR3H -0.76 -9.1 -0.44 7.89e-18 Neuroticism; LIHC cis rs45544231 0.569 rs9302556 chr16:52543645 C/A cg09051775 chr16:52580266 TOX3 -0.32 -5.77 -0.3 1.77e-8 Restless legs syndrome; LIHC cis rs4888262 0.508 rs4462623 chr16:74692426 C/T cg01733217 chr16:74700730 RFWD3 0.87 18.25 0.7 1.98e-52 Testicular germ cell tumor; LIHC cis rs116248771 0.549 rs4680461 chr3:158454160 C/G cg16708174 chr3:158430962 RARRES1 0.7 8.95 0.44 2.38e-17 diarrhoeal disease at age 2; LIHC cis rs77741769 0.529 rs909053 chr12:121237668 G/A cg02419362 chr12:121203948 SPPL3 0.33 5.77 0.3 1.76e-8 Mean corpuscular volume; LIHC cis rs2455601 1.000 rs56336128 chr11:8908299 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.5 -6.49 -0.33 2.94e-10 Schizophrenia; LIHC cis rs2412459 0.831 rs6492924 chr15:40272391 G/A cg20255370 chr15:40268687 EIF2AK4 -0.6 -8.1 -0.4 9.64e-15 Response to haloperidol in psychosis; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg05064044 chr6:292385 DUSP22 -0.53 -6.92 -0.35 2.26e-11 Menopause (age at onset); LIHC cis rs6141600 0.506 rs2590990 chr20:34671179 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.61 -0.34 1.48e-10 Height;Hip circumference; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg13409248 chr3:40428643 ENTPD3 -0.5 -8.4 -0.41 1.23e-15 Renal cell carcinoma; LIHC cis rs2832191 0.646 rs2832214 chr21:30517127 C/T cg08807101 chr21:30365312 RNF160 -0.43 -6.07 -0.31 3.39e-9 Dental caries; LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg00656387 chr3:40428638 ENTPD3 0.48 7.93 0.39 3.13e-14 Renal cell carcinoma; LIHC cis rs9790314 1.000 rs6441373 chr3:161026717 T/G cg03342759 chr3:160939853 NMD3 -0.72 -8.78 -0.43 7.96e-17 Morning vs. evening chronotype; LIHC cis rs11148252 0.564 rs2296350 chr13:52710044 T/C cg12458913 chr13:53173898 NA 0.35 6.01 0.31 4.79e-9 Lewy body disease; LIHC cis rs1691799 0.867 rs1168316 chr12:66746239 A/G cg16791601 chr12:66731901 HELB -0.56 -13.94 -0.6 2.85e-35 White blood cell count (basophil); LIHC trans rs11098499 0.820 rs11737395 chr4:120520704 C/G cg25214090 chr10:38739885 LOC399744 0.59 9.66 0.46 1.08e-19 Corneal astigmatism; LIHC cis rs11055008 0.935 rs10845601 chr12:12820134 A/G cg09462578 chr12:12878428 APOLD1 0.55 8.18 0.4 5.71e-15 Pulse pressure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11381792 chr21:45432451 TRAPPC10 0.6 7.95 0.39 2.78e-14 Lung function (FEV1/FVC); LIHC cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg20570016 chr1:156261298 TMEM79 -0.35 -5.75 -0.3 2.01e-8 Tonsillectomy; LIHC trans rs6489882 0.867 rs4766665 chr12:113363109 T/C cg10175203 chr3:128143634 NA 0.39 6.38 0.33 5.72e-10 Chronic lymphocytic leukemia; LIHC cis rs1003719 0.654 rs764175 chr21:38517058 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.15 -0.52 7.67e-25 Eye color traits; LIHC cis rs7772486 0.790 rs6570723 chr6:146151230 A/T cg23711669 chr6:146136114 FBXO30 0.64 11.49 0.53 4.8e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs332507 0.601 rs7618562 chr3:124363001 A/G cg05980111 chr3:124395277 KALRN 0.31 5.93 0.31 7.3e-9 Plateletcrit; LIHC cis rs9902453 0.612 rs2617868 chr17:28073247 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.47 -0.59 1.77e-33 Coffee consumption (cups per day); LIHC cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9611565 0.546 rs739134 chr22:42089623 T/C cg03806693 chr22:41940476 POLR3H 0.83 9.32 0.45 1.51e-18 Vitiligo; LIHC cis rs875971 0.862 rs778697 chr7:65870426 G/A cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC cis rs11588062 0.628 rs3737744 chr1:46810530 C/T cg23431851 chr1:46668822 C1orf190;POMGNT1 -0.42 -6.79 -0.34 5.06e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7520050 0.902 rs4638056 chr1:46458153 T/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.43 6.34 0.32 7.42e-10 Red blood cell count;Reticulocyte count; LIHC cis rs13191362 0.935 rs66507030 chr6:162953825 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.76 0.3 1.92e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs950169 0.579 rs12912716 chr15:84664263 A/T cg24036039 chr1:3397125 ARHGEF16 0.39 6.39 0.33 5.58e-10 Schizophrenia; LIHC cis rs4728302 0.869 rs6969899 chr7:133597490 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.47 0.33 3.37e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs6941670 chr6:8446346 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.39 0.41 1.32e-15 Motion sickness; LIHC cis rs9322817 0.669 rs4079063 chr6:105266118 A/G cg02098413 chr6:105308735 HACE1 -0.43 -8.05 -0.4 1.34e-14 Thyroid stimulating hormone; LIHC cis rs9733 0.628 rs72700895 chr1:150626029 C/T cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs4665809 1.000 rs6739061 chr2:26256147 C/T cg27170947 chr2:26402098 FAM59B -0.66 -8.21 -0.41 4.61e-15 Gut microbiome composition (summer); LIHC cis rs4819052 0.918 rs34886433 chr21:46680538 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.67 8.53 0.42 4.89e-16 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10883723 0.810 rs7090034 chr10:104281155 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.17e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7572733 0.534 rs700683 chr2:198712332 G/A cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs807669 0.770 rs807458 chr22:19220648 G/A cg26795923 chr22:19165960 SLC25A1 0.81 6.41 0.33 4.7e-10 Metabolite levels; LIHC cis rs11971779 0.680 rs7804388 chr7:139086413 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2795502 0.872 rs2744062 chr10:43254789 T/A cg20628663 chr10:43360327 NA -0.46 -6.93 -0.35 2.14e-11 Blood protein levels; LIHC cis rs5769765 0.955 rs5770750 chr22:50276828 A/G cg02269571 chr22:50332266 NA 0.61 8.64 0.42 2.24e-16 Schizophrenia; LIHC cis rs1144333 1.000 rs1021464 chr1:76375415 G/A cg10523679 chr1:76189770 ACADM 0.45 6.52 0.33 2.58e-10 Attention function in attention deficit hyperactive disorder; LIHC trans rs634534 0.562 rs642293 chr11:65730217 G/A cg17712092 chr4:129076599 LARP1B 0.73 12.86 0.57 3.67e-31 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs6001982 0.541 rs56203629 chr22:41049685 T/A cg14879645 chr22:41048474 NA 0.4 5.82 0.3 1.35e-8 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02158565 chr7:150788256 AGAP3 -0.53 -6.91 -0.35 2.44e-11 Lung function (FEV1/FVC); LIHC cis rs2197308 0.765 rs11182481 chr12:37926019 T/C cg26384229 chr12:38710491 ALG10B 0.85 10.95 0.51 4.18e-24 Morning vs. evening chronotype; LIHC cis rs3740540 0.761 rs34042290 chr10:126286806 G/A cg20435097 chr10:126320824 FAM53B 0.53 7.78 0.39 8.68e-14 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs10193935 0.901 rs7605782 chr2:42502332 C/T cg27598129 chr2:42591480 NA -0.71 -10.57 -0.5 8.53e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs12464483 0.556 rs2609934 chr2:30895979 G/A cg17749961 chr2:30669863 LCLAT1 0.44 5.71 0.3 2.45e-8 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs3768617 0.727 rs12066735 chr1:183101451 T/G ch.1.3577855R chr1:183094577 LAMC1 0.48 7.65 0.38 2.02e-13 Fuchs's corneal dystrophy; LIHC cis rs11764590 0.694 rs11762413 chr7:2090387 C/G cg23043544 chr7:2124092 MAD1L1 -0.48 -7.88 -0.39 4.49e-14 Neuroticism; LIHC cis rs17376456 0.825 rs10078941 chr5:93279029 C/T cg25358565 chr5:93447407 FAM172A 1.07 9.61 0.46 1.62e-19 Diabetic retinopathy; LIHC cis rs10876993 0.890 rs799575 chr12:58069107 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.03 -0.31 4.34e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg16606324 chr3:10149918 C3orf24 0.54 5.81 0.3 1.4e-8 Alzheimer's disease; LIHC cis rs1670533 1.000 rs6852155 chr4:1067638 T/G cg27284194 chr4:1044797 NA 0.61 9.1 0.44 7.85e-18 Recombination rate (females); LIHC cis rs9399135 0.967 rs9389253 chr6:135329755 T/C cg24558204 chr6:135376177 HBS1L 0.42 6.96 0.35 1.72e-11 Red blood cell count; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg22037798 chr1:231473786 C1orf124;EXOC8 -0.49 -6.62 -0.34 1.38e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1878931 0.582 rs9635562 chr16:3416689 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.69 9.15 0.44 5.39e-18 Body mass index (adult); LIHC cis rs4713118 0.513 rs149954 chr6:28035246 G/A cg23485639 chr6:28045615 ZNF165 0.38 5.77 0.3 1.78e-8 Parkinson's disease; LIHC trans rs35110281 0.811 rs2838337 chr21:45072621 A/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.26 0.32 1.15e-9 Mean corpuscular volume; LIHC cis rs4654899 1.000 rs10916938 chr1:21446883 A/G cg08539965 chr1:21396338 EIF4G3 0.32 5.77 0.3 1.81e-8 Superior frontal gyrus grey matter volume; LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg10755058 chr3:40428713 ENTPD3 0.41 6.89 0.35 2.77e-11 Renal cell carcinoma; LIHC cis rs367615 0.552 rs2963022 chr5:108727185 A/G cg17395555 chr5:108820864 NA -0.28 -6.11 -0.31 2.65e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs704795 0.702 rs11689803 chr2:27566520 T/A cg27432699 chr2:27873401 GPN1 -0.65 -6.3 -0.32 9.19e-10 Menopause (age at onset); LIHC cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg14983838 chr19:29218262 NA 0.49 7.77 0.39 9.03e-14 Methadone dose in opioid dependence; LIHC cis rs10416265 0.502 rs7245411 chr19:33543029 A/T cg27124370 chr19:33622961 WDR88 0.58 8.42 0.41 1.08e-15 Bone properties (heel); LIHC cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs1568889 0.730 rs6484350 chr11:28113658 G/A cg06544937 chr11:28130018 METT5D1;KIF18A -0.67 -14.01 -0.6 1.44e-35 Bipolar disorder; LIHC cis rs7208859 0.673 rs56146117 chr17:29153325 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.0 0.4 1.97e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg04944784 chr2:26401820 FAM59B -0.77 -9.44 -0.45 6.02e-19 Gut microbiome composition (summer); LIHC cis rs2404602 0.735 rs3765115 chr15:76673716 T/C cg03037974 chr15:76606532 NA -0.65 -11.53 -0.53 3.35e-26 Blood metabolite levels; LIHC cis rs3806843 0.705 rs35614340 chr5:140043618 C/G cg19875535 chr5:140030758 IK -0.41 -6.7 -0.34 8.86e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs67478160 0.608 rs4906368 chr14:104242397 A/C cg01849466 chr14:104193079 ZFYVE21 -0.53 -9.24 -0.45 2.67e-18 Schizophrenia; LIHC cis rs9916302 0.861 rs11078896 chr17:37415544 C/T cg00129232 chr17:37814104 STARD3 -0.37 -5.99 -0.31 5.22e-9 Glomerular filtration rate (creatinine); LIHC trans rs10242455 0.702 rs73397499 chr7:99039627 T/C cg09045935 chr12:6379348 NA 0.84 6.91 0.35 2.41e-11 Blood metabolite levels; LIHC cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg06238570 chr21:40685208 BRWD1 0.6 7.09 0.36 7.97e-12 Cognitive function; LIHC cis rs16866061 0.515 rs3738951 chr2:225368321 A/G cg12698349 chr2:225449008 CUL3 0.89 20.2 0.74 2.71e-60 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs7246657 0.943 rs10405325 chr19:37883477 G/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs1494950 1.000 rs7668863 chr4:15088863 G/A cg12377275 chr4:15005593 CPEB2 -0.84 -7.49 -0.38 5.92e-13 Political ideology; LIHC cis rs2067615 0.599 rs10778508 chr12:107159405 A/G cg15890332 chr12:107067104 RFX4 -0.26 -6.02 -0.31 4.57e-9 Heart rate; LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg11494091 chr17:61959527 GH2 0.35 5.92 0.3 7.8e-9 Height; LIHC cis rs4689592 0.554 rs3951346 chr4:7073321 C/T cg02503808 chr4:7069936 GRPEL1 0.79 11.95 0.54 9.51e-28 Monocyte percentage of white cells; LIHC cis rs2303759 0.709 rs10414921 chr19:49823047 C/T cg22307029 chr19:49891270 CCDC155 0.56 8.62 0.42 2.52e-16 Multiple sclerosis; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg11890956 chr21:40555474 PSMG1 1.07 16.04 0.66 1.47e-43 Cognitive function; LIHC cis rs6539247 0.509 rs2374584 chr12:106445988 C/T cg20883310 chr12:106464547 NUAK1 0.45 7.26 0.37 2.57e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs17401966 1.000 rs17401966 chr1:10385471 C/T cg15208524 chr1:10270712 KIF1B -0.44 -6.4 -0.33 5.04e-10 Hepatocellular carcinoma; LIHC cis rs3768617 0.510 rs10797844 chr1:183082067 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.72 0.5 2.59e-23 Fuchs's corneal dystrophy; LIHC cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs9290065 0.622 rs6797798 chr3:160646598 G/A cg03342759 chr3:160939853 NMD3 0.6 8.14 0.4 7.31e-15 Kawasaki disease; LIHC cis rs10861342 1.000 rs10861346 chr12:105473245 G/T cg23923672 chr12:105501055 KIAA1033 0.61 7.38 0.37 1.2e-12 IgG glycosylation; LIHC cis rs2153535 0.580 rs2225766 chr6:8481833 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs4808199 0.947 rs7250658 chr19:19571100 A/G cg21559469 chr19:19431446 KIAA0892;SF4 0.43 5.79 0.3 1.6e-8 Nonalcoholic fatty liver disease; LIHC cis rs72781680 1.000 rs12623496 chr2:24181583 C/T cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.28e-14 Lymphocyte counts; LIHC cis rs34779708 0.931 rs12773169 chr10:35366462 G/C cg03585969 chr10:35415529 CREM 0.85 12.9 0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.33 0.41 1.94e-15 Height; LIHC trans rs11157436 0.958 rs3811277 chr14:22658313 C/T cg13567813 chr19:50879636 NR1H2 0.43 6.14 0.32 2.26e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs2153535 0.580 rs6941670 chr6:8446346 G/A cg07606381 chr6:8435919 SLC35B3 0.78 11.54 0.53 3.17e-26 Motion sickness; LIHC cis rs1055129 0.560 rs3682 chr17:73942150 A/G cg14829360 chr17:73884958 NA -0.37 -6.25 -0.32 1.23e-9 White matter hyperintensity burden; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16919356 chr7:150780878 TMUB1 0.44 6.49 0.33 3.09e-10 Pancreatic cancer; LIHC cis rs2204008 0.652 rs11520002 chr12:38022179 G/T cg26384229 chr12:38710491 ALG10B 0.85 10.57 0.5 9e-23 Bladder cancer; LIHC cis rs12142240 0.698 rs66972124 chr1:46807445 A/G cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg19774624 chr17:42201019 HDAC5 0.67 9.96 0.47 1.14e-20 Total body bone mineral density; LIHC cis rs12368653 0.666 rs701007 chr12:58113416 C/A cg12615879 chr12:58013172 SLC26A10 0.35 7.04 0.36 1.09e-11 Multiple sclerosis; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs8060686 0.516 rs255052 chr16:68024995 C/T cg05110241 chr16:68378359 PRMT7 -0.51 -5.72 -0.3 2.37e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs11758351 0.929 rs6906367 chr6:26187125 C/T cg16070018 chr6:26224392 HIST1H3E 0.51 6.92 0.35 2.26e-11 Gout;Renal underexcretion gout; LIHC cis rs12477438 0.798 rs6740267 chr2:99561867 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.76 -11.24 -0.52 3.77e-25 Chronic sinus infection; LIHC cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg22963979 chr7:1858916 MAD1L1 -0.4 -6.41 -0.33 4.81e-10 Bipolar disorder and schizophrenia; LIHC trans rs7615952 0.673 rs3811677 chr3:125648080 G/A cg07211511 chr3:129823064 LOC729375 -0.84 -10.39 -0.49 3.56e-22 Blood pressure (smoking interaction); LIHC cis rs7523273 0.925 rs10863593 chr1:208018074 C/T cg22525895 chr1:207977042 MIR29B2 0.61 9.3 0.45 1.66e-18 Schizophrenia; LIHC cis rs116095464 0.558 rs9654453 chr5:299621 T/C cg22857025 chr5:266934 NA -1.49 -15.31 -0.64 1.14e-40 Breast cancer; LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs8072100 0.811 rs9889709 chr17:45445229 C/T cg08085267 chr17:45401833 C17orf57 -0.58 -8.64 -0.42 2.22e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs11971779 0.648 rs4732367 chr7:139028102 A/C cg07862535 chr7:139043722 LUC7L2 0.59 10.16 0.48 2.35e-21 Diisocyanate-induced asthma; LIHC cis rs6963495 0.556 rs818474 chr7:105155243 A/T cg19920283 chr7:105172520 RINT1 0.47 5.97 0.31 5.97e-9 Bipolar disorder (body mass index interaction); LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg20887711 chr4:1340912 KIAA1530 0.81 12.8 0.57 6.53e-31 Longevity; LIHC cis rs208520 0.690 rs12213561 chr6:66705646 T/C cg07460842 chr6:66804631 NA 0.74 8.61 0.42 2.8e-16 Exhaled nitric oxide output; LIHC cis rs6500602 0.893 rs4786490 chr16:4491190 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.41 -6.4 -0.33 5.06e-10 Schizophrenia; LIHC cis rs258892 0.895 rs266437 chr5:72167441 G/C cg21869765 chr5:72125136 TNPO1 0.39 5.75 0.3 1.93e-8 Small cell lung carcinoma; LIHC cis rs11675119 0.513 rs9752321 chr2:3494374 A/G cg10845886 chr2:3471009 TTC15 -0.44 -7.81 -0.39 6.99e-14 Neurofibrillary tangles; LIHC cis rs11098699 0.769 rs13136692 chr4:124229169 G/A cg09941581 chr4:124220074 SPATA5 0.33 6.59 0.34 1.68e-10 Mosquito bite size; LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.575 rs7107213 chr11:111750430 A/G cg09085632 chr11:111637200 PPP2R1B 0.96 13.89 0.6 4.43e-35 Primary sclerosing cholangitis; LIHC trans rs17685 0.753 rs1104878 chr7:75685593 G/T cg19862616 chr7:65841803 NCRNA00174 0.92 19.18 0.72 3.65e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17376456 0.877 rs17316137 chr5:93456577 C/T cg25358565 chr5:93447407 FAM172A 1.08 10.06 0.48 5.12e-21 Diabetic retinopathy; LIHC cis rs2836950 0.545 rs2836922 chr21:40516308 C/T cg17971929 chr21:40555470 PSMG1 -0.38 -5.72 -0.3 2.29e-8 Menarche (age at onset); LIHC cis rs1552244 0.572 rs6797536 chr3:10168802 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 0.86 9.5 0.46 3.93e-19 Alzheimer's disease; LIHC cis rs709400 0.567 rs28496120 chr14:103897899 C/T cg26031613 chr14:104095156 KLC1 0.74 10.01 0.48 7.59e-21 Body mass index; LIHC cis rs12477438 0.520 rs11123764 chr2:99750677 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.38 0.59 3.85e-33 Chronic sinus infection; LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg00800038 chr16:89945340 TCF25 -0.6 -9.78 -0.47 4.42e-20 Skin colour saturation; LIHC cis rs2072499 0.966 rs2842882 chr1:156165342 T/G cg24450063 chr1:156163899 SLC25A44 1.08 18.76 0.71 1.68e-54 Testicular germ cell tumor; LIHC cis rs36051895 0.659 rs10283730 chr9:5073289 G/A cg02405213 chr9:5042618 JAK2 -0.68 -11.41 -0.53 8.88e-26 Pediatric autoimmune diseases; LIHC cis rs3780378 0.967 rs10815144 chr9:5010192 C/T cg02405213 chr9:5042618 JAK2 -0.55 -9.62 -0.46 1.46e-19 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs2625529 0.730 rs8182011 chr15:72389948 C/T cg16672083 chr15:72433130 SENP8 0.3 5.84 0.3 1.19e-8 Red blood cell count; LIHC cis rs7267979 1.000 rs2257982 chr20:25269630 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2439831 0.850 rs3759790 chr15:44121030 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.33 0.41 2.02e-15 Lung cancer in ever smokers; LIHC cis rs75064307 0.834 rs4855562 chr3:108116835 C/T cg03329597 chr3:108125523 MYH15 0.52 7.09 0.36 7.55e-12 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26084319 chr14:21905280 CHD8 0.56 7.95 0.39 2.66e-14 Pancreatic cancer; LIHC cis rs2834256 0.552 rs7276923 chr21:34868761 A/G cg14850771 chr21:34775459 IFNGR2 0.47 7.77 0.39 9.31e-14 Red cell distribution width; LIHC cis rs57221529 0.766 rs12522303 chr5:555564 A/C cg09021430 chr5:549028 NA -0.46 -9.13 -0.44 5.9e-18 Lung disease severity in cystic fibrosis; LIHC cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.22 0.52 4.31e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs1003719 0.715 rs2835644 chr21:38545610 G/T cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs5769765 0.955 rs8138687 chr22:50291869 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.16 -0.44 4.85e-18 Schizophrenia; LIHC cis rs8180040 0.966 rs922957 chr3:47422152 G/C cg27129171 chr3:47204927 SETD2 -0.57 -9.5 -0.46 3.9e-19 Colorectal cancer; LIHC cis rs1801251 1.000 rs2044449 chr2:233718808 G/A cg08000102 chr2:233561755 GIGYF2 -0.76 -11.55 -0.53 2.7e-26 Coronary artery disease; LIHC cis rs41271473 0.526 rs10916337 chr1:228714902 C/T cg10167378 chr1:228756711 NA 0.65 6.73 0.34 6.98e-11 Chronic lymphocytic leukemia; LIHC cis rs7659604 0.539 rs3217753 chr4:122746325 A/G cg20573242 chr4:122745356 CCNA2 0.51 7.57 0.38 3.55e-13 Type 2 diabetes; LIHC cis rs8180040 0.726 rs13094672 chr3:47149439 C/T cg16586182 chr3:47516702 SCAP -0.5 -9.01 -0.44 1.48e-17 Colorectal cancer; LIHC cis rs4789452 0.934 rs3987888 chr17:75370274 T/C cg05865280 chr17:75406074 SEPT9 0.35 7.5 0.38 5.49e-13 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs9911578 1.000 rs2611782 chr17:56717956 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.754 rs9390358 chr6:146145678 C/T cg13319975 chr6:146136371 FBXO30 -0.36 -6.08 -0.31 3.13e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14624505 chr17:4843538 SLC25A11;RNF167 -0.52 -6.09 -0.31 3.08e-9 Systolic blood pressure; LIHC cis rs57590327 0.555 rs13062054 chr3:81833906 A/G cg07356753 chr3:81810745 GBE1 -0.57 -8.9 -0.43 3.42e-17 Extraversion; LIHC cis rs35110281 0.811 rs2838339 chr21:45075750 A/G cg04455712 chr21:45112962 RRP1B -0.44 -7.5 -0.38 5.51e-13 Mean corpuscular volume; LIHC cis rs7927592 1.000 rs7927592 chr11:68369960 G/A cg20283391 chr11:68216788 NA -0.51 -7.53 -0.38 4.48e-13 Total body bone mineral density; LIHC cis rs151997 0.925 rs27286 chr5:50196324 G/T cg06027927 chr5:50259733 NA 0.57 7.58 0.38 3.33e-13 Callous-unemotional behaviour; LIHC cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.35 0.37 1.5e-12 Obesity-related traits; LIHC cis rs9916302 0.706 rs801418 chr17:37457982 G/C cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs72781680 0.821 rs11894756 chr2:24170214 A/G cg08917208 chr2:24149416 ATAD2B -0.65 -6.59 -0.34 1.64e-10 Lymphocyte counts; LIHC cis rs7617773 1.000 rs12496784 chr3:48186267 C/T cg11946769 chr3:48343235 NME6 -0.6 -8.17 -0.4 6.2e-15 Coronary artery disease; LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.68 9.77 0.47 4.84e-20 Lymphocyte counts; LIHC cis rs1538970 0.781 rs12049503 chr1:46021556 G/T cg06784218 chr1:46089804 CCDC17 0.37 6.05 0.31 3.74e-9 Platelet count; LIHC cis rs3770081 1.000 rs17584578 chr2:86307624 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 -0.44 -6.54 -0.33 2.19e-10 Facial emotion recognition (sad faces); LIHC trans rs2270927 0.510 rs2972839 chr5:75572943 C/T cg13563193 chr19:33072644 PDCD5 0.85 8.01 0.4 1.83e-14 Mean corpuscular volume; LIHC cis rs6933660 0.760 rs3806982 chr6:151774916 G/A cg14262678 chr6:151773367 RMND1;C6orf211 0.51 7.42 0.37 9.22e-13 Menarche (age at onset); LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs6988636 1.000 rs62521841 chr8:124194625 G/A cg15893493 chr8:124194847 FAM83A 0.81 7.81 0.39 7.07e-14 Urinary uromodulin levels; LIHC cis rs939574 1.000 rs11689596 chr2:220093423 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.94 -10.34 -0.49 5.3e-22 Platelet distribution width; LIHC cis rs11190604 0.652 rs76629555 chr10:102191417 T/C cg07080220 chr10:102295463 HIF1AN 0.47 6.93 0.35 2.08e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg09417038 chr21:47716443 C21orf57 -0.5 -7.69 -0.38 1.62e-13 Testicular germ cell tumor; LIHC cis rs10876993 1.000 rs10876993 chr12:58062667 C/T cg15848620 chr12:58087721 OS9 -0.54 -7.31 -0.37 1.9e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs35883536 1.000 rs4907921 chr1:101128249 C/T cg14515779 chr1:101123966 NA -0.7 -14.08 -0.61 7.92e-36 Monocyte count; LIHC cis rs9612 1.000 rs8105041 chr19:44258458 A/G cg08581076 chr19:44259116 C19orf61 0.7 8.95 0.44 2.37e-17 Exhaled nitric oxide output; LIHC cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg07414643 chr4:187882934 NA 0.25 6.4 0.33 5.19e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.601 rs3778978 chr7:2159817 A/G cg20295408 chr7:1910781 MAD1L1 -0.42 -6.16 -0.32 2.08e-9 Bipolar disorder and schizophrenia; LIHC cis rs5769765 0.542 rs1033666 chr22:50252783 T/C cg09182678 chr22:50328711 NA 0.47 6.0 0.31 5.14e-9 Schizophrenia; LIHC cis rs6088580 0.543 rs4911158 chr20:33239512 T/C cg08999081 chr20:33150536 PIGU -0.43 -7.18 -0.36 4.44e-12 Glomerular filtration rate (creatinine); LIHC trans rs8117834 0.574 rs6118062 chr20:8087581 T/C cg00593689 chr4:53575888 NA 0.38 6.38 0.33 5.83e-10 Chronic kidney disease; LIHC trans rs11098499 0.657 rs9996569 chr4:120299004 G/C cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs2806561 0.765 rs2806556 chr1:23502850 G/A cg12483005 chr1:23474871 LUZP1 0.47 7.48 0.38 6.16e-13 Height; LIHC cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs57590327 0.679 rs62265397 chr3:81543883 A/T cg07356753 chr3:81810745 GBE1 -0.43 -5.97 -0.31 5.79e-9 Extraversion; LIHC cis rs2075371 1.000 rs1421484 chr7:133979795 T/C cg11752832 chr7:134001865 SLC35B4 0.49 7.5 0.38 5.69e-13 Mean platelet volume; LIHC cis rs2412819 0.597 rs78282429 chr15:43922003 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.38 6.21 0.32 1.57e-9 Lung cancer; LIHC cis rs9296092 0.517 rs62405895 chr6:33471969 G/T cg13560919 chr6:33536144 NA -0.39 -5.98 -0.31 5.63e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs965469 0.553 rs6051767 chr20:3324521 C/T cg25506879 chr20:3388711 C20orf194 -0.54 -7.42 -0.37 9.33e-13 IFN-related cytopenia; LIHC cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg06481639 chr22:41940642 POLR3H -0.73 -6.86 -0.35 3.32e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9457247 1.000 rs444988 chr6:167389674 A/T cg12798992 chr6:167411361 FGFR1OP 0.52 8.05 0.4 1.37e-14 Crohn's disease; LIHC cis rs208520 0.874 rs208515 chr6:66945749 A/G cg07460842 chr6:66804631 NA -0.7 -7.69 -0.38 1.63e-13 Exhaled nitric oxide output; LIHC cis rs202629 1 rs202629 chr22:41849975 C/T cg03806693 chr22:41940476 POLR3H 1.05 12.51 0.56 8.16e-30 Cannabis dependence symptom count; LIHC cis rs1538970 0.884 rs781226 chr1:45872662 T/C cg05343316 chr1:45956843 TESK2 -0.52 -7.59 -0.38 3.07e-13 Platelet count; LIHC cis rs2153535 0.580 rs9393022 chr6:8466588 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg04944784 chr2:26401820 FAM59B -0.72 -9.24 -0.45 2.67e-18 Gut microbiome composition (summer); LIHC cis rs6500602 0.702 rs2270366 chr16:4558615 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.5 -7.91 -0.39 3.55e-14 Schizophrenia; LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg14159672 chr1:205819179 PM20D1 0.75 10.54 0.5 1.1e-22 Menarche (age at onset); LIHC cis rs7843479 0.930 rs2054713 chr8:21840534 A/G cg17168535 chr8:21777572 XPO7 0.4 6.61 0.34 1.46e-10 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC cis rs12022452 0.630 rs3795346 chr1:40974425 T/C cg25568243 chr1:40974465 DEM1 0.45 6.07 0.31 3.37e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10504229 0.636 rs10958525 chr8:58051528 C/A cg20607798 chr8:58055168 NA 0.47 6.45 0.33 3.79e-10 Developmental language disorder (linguistic errors); LIHC cis rs9682041 0.866 rs6444926 chr3:170133235 T/C cg11886554 chr3:170076028 SKIL 0.91 6.54 0.33 2.26e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg05368731 chr17:41323189 NBR1 0.73 12.45 0.56 1.39e-29 Menopause (age at onset); LIHC cis rs12701220 0.604 rs34904312 chr7:1135883 G/A cg00990874 chr7:1149470 C7orf50 -0.69 -9.89 -0.47 1.87e-20 Bronchopulmonary dysplasia; LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg02990361 chr1:107599529 PRMT6 -0.59 -9.53 -0.46 2.99e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6840360 0.571 rs17360371 chr4:152565374 C/T cg22705602 chr4:152727874 NA -0.35 -6.68 -0.34 9.61e-11 Intelligence (multi-trait analysis); LIHC cis rs9649213 0.574 rs7802560 chr7:97903806 A/G cg08684580 chr7:98029266 BAIAP2L1 0.39 6.2 0.32 1.63e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.87 0.57 3.48e-31 Prudent dietary pattern; LIHC cis rs9611565 0.608 rs2003816 chr22:42095140 T/G cg03806693 chr22:41940476 POLR3H 0.8 9.07 0.44 9.78e-18 Vitiligo; LIHC trans rs11148252 0.574 rs7139495 chr13:53283318 A/G cg18335740 chr13:41363409 SLC25A15 0.57 10.5 0.49 1.59e-22 Lewy body disease; LIHC trans rs11098499 0.955 rs7684942 chr4:120162201 C/T cg25214090 chr10:38739885 LOC399744 0.52 7.95 0.39 2.75e-14 Corneal astigmatism; LIHC cis rs35306767 0.903 rs17159970 chr10:935601 T/C cg20503657 chr10:835505 NA 1.04 11.8 0.54 3.42e-27 Eosinophil percentage of granulocytes; LIHC cis rs2439831 1.000 rs550239 chr15:43720197 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.94 0.44 2.46e-17 Lung cancer in ever smokers; LIHC cis rs600806 0.778 rs2152924 chr1:110011701 G/A cg16275483 chr1:110013120 SYPL2 -0.49 -6.22 -0.32 1.42e-9 Intelligence (multi-trait analysis); LIHC cis rs7909074 0.865 rs10900123 chr10:45376574 C/T cg04218760 chr10:45406644 TMEM72 -0.25 -7.66 -0.38 1.96e-13 Mean corpuscular volume; LIHC cis rs6674176 0.597 rs4660262 chr1:44382524 G/A cg12908607 chr1:44402522 ARTN -0.5 -8.61 -0.42 2.69e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs3749237 0.929 rs62260715 chr3:49829326 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.67 10.25 0.48 1.1e-21 Resting heart rate; LIHC cis rs9517313 0.565 rs9556978 chr13:99234648 G/A cg07423050 chr13:99094983 FARP1 -0.45 -7.5 -0.38 5.38e-13 Neuroticism; LIHC cis rs8084351 0.577 rs9952089 chr18:50619266 A/G cg24270629 chr18:50823537 DCC 0.43 6.54 0.33 2.25e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs16866061 1.000 rs72974269 chr2:225454907 C/T cg12698349 chr2:225449008 CUL3 0.79 13.85 0.6 5.96e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs8033655 0.963 rs2899446 chr15:50307416 A/G cg10099229 chr12:6960622 USP5;CDCA3 0.43 6.16 0.32 2.01e-9 Skin pigmentation; LIHC cis rs9457247 0.624 rs2239826 chr6:167504880 T/C cg12798992 chr6:167411361 FGFR1OP 0.43 6.45 0.33 3.85e-10 Crohn's disease; LIHC cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg11279151 chr3:101281821 RG9MTD1 0.52 7.65 0.38 2e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs7091068 0.536 rs6583901 chr10:95409998 C/T cg20715218 chr10:95462985 C10orf4 -0.54 -8.32 -0.41 2.19e-15 Urinary tract infection frequency; LIHC trans rs4799915 1.000 rs3865392 chr18:34929464 G/T cg11874882 chr17:31910113 ACCN1 -0.26 -6.08 -0.31 3.14e-9 Response to iloperidone treatment (QT prolongation); LIHC cis rs11971779 0.715 rs6467853 chr7:139127027 A/G cg07862535 chr7:139043722 LUC7L2 0.59 9.92 0.47 1.46e-20 Diisocyanate-induced asthma; LIHC cis rs7712401 0.791 rs6887101 chr5:122109207 C/T cg18764291 chr5:122110994 SNX2 -0.36 -6.25 -0.32 1.19e-9 Mean platelet volume; LIHC cis rs7584330 0.910 rs880930 chr2:238396872 G/C cg14458575 chr2:238380390 NA 0.38 5.76 0.3 1.83e-8 Prostate cancer; LIHC trans rs11098499 0.863 rs3822192 chr4:120445720 A/C cg25214090 chr10:38739885 LOC399744 0.63 10.2 0.48 1.72e-21 Corneal astigmatism; LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg14893161 chr1:205819251 PM20D1 0.68 9.83 0.47 2.97e-20 Menarche (age at onset); LIHC cis rs9291683 0.588 rs35438220 chr4:9999398 C/T cg11266682 chr4:10021025 SLC2A9 0.31 6.44 0.33 4.13e-10 Bone mineral density; LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg22963979 chr7:1858916 MAD1L1 -0.44 -7.31 -0.37 1.87e-12 Bipolar disorder and schizophrenia; LIHC cis rs9549367 0.789 rs12584813 chr13:113895443 C/G cg00898013 chr13:113819073 PROZ -0.4 -6.96 -0.35 1.77e-11 Platelet distribution width; LIHC cis rs79247733 0.786 rs2286442 chr22:30772686 C/T cg03868770 chr22:30783737 RNF215 -0.47 -6.14 -0.32 2.3e-9 Tonsillectomy; LIHC cis rs6545883 0.929 rs6545877 chr2:61741947 T/C cg15711740 chr2:61764176 XPO1 -0.43 -6.08 -0.31 3.22e-9 Tuberculosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22627950 chr7:44622302 TMED4 0.41 6.27 0.32 1.08e-9 Cognitive function; LIHC cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg25072359 chr17:41440525 NA 0.37 5.79 0.3 1.57e-8 Menopause (age at onset); LIHC cis rs8180040 0.764 rs11712716 chr3:47193432 T/C cg02527881 chr3:46936655 PTH1R -0.32 -6.33 -0.32 7.83e-10 Colorectal cancer; LIHC cis rs2066819 1.000 rs2695788 chr12:56697110 G/A cg26734620 chr12:56694298 CS -0.98 -9.85 -0.47 2.57e-20 Psoriasis vulgaris; LIHC cis rs8177253 0.507 rs4241357 chr3:133475563 A/C cg16262614 chr3:133464971 TF -0.37 -7.99 -0.4 2.08e-14 Iron status biomarkers; LIHC cis rs10876993 0.928 rs1678530 chr12:58054076 A/C cg04478727 chr12:58166393 METTL1;FAM119B -0.47 -6.72 -0.34 7.55e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs1577917 0.958 rs34230196 chr6:86526022 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.99 -0.4 2.13e-14 Lymphocyte counts; LIHC cis rs4073582 0.595 rs9326370 chr11:65992008 A/G cg14036092 chr11:66035641 RAB1B 0.41 6.49 0.33 3.11e-10 Gout; LIHC trans rs1814175 0.817 rs6486044 chr11:49982718 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs898097 0.528 rs2243523 chr17:80680449 G/T cg15664640 chr17:80829946 TBCD -0.45 -7.45 -0.37 7.46e-13 Breast cancer; LIHC cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg00106254 chr7:1943704 MAD1L1 0.4 6.28 0.32 1.01e-9 Bipolar disorder and schizophrenia; LIHC cis rs11112613 0.609 rs4388999 chr12:106047758 G/T cg03607813 chr12:105948248 NA 0.4 6.27 0.32 1.11e-9 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23296058 chr5:86708877 CCNH 0.46 6.06 0.31 3.6e-9 Lung function (FEV1/FVC); LIHC cis rs2073300 0.609 rs6137945 chr20:23406136 C/T cg12062639 chr20:23401060 NAPB 1.03 13.28 0.58 9.93e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2576037 0.583 rs646128 chr18:44397691 A/C cg19077165 chr18:44547161 KATNAL2 -0.47 -6.78 -0.34 5.18e-11 Personality dimensions; LIHC cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg03517284 chr6:25882590 NA -0.6 -7.44 -0.37 8.39e-13 Intelligence (multi-trait analysis); LIHC trans rs2018683 0.770 rs10951208 chr7:29022504 G/T cg19402173 chr7:128379420 CALU -0.4 -6.29 -0.32 9.87e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs77861329 1.000 rs13319566 chr3:52095555 C/G cg08692210 chr3:52188851 WDR51A 0.84 7.93 0.39 3.05e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs2153535 0.541 rs1414347 chr6:8471831 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs4742903 1.000 rs3739736 chr9:106857908 G/A cg14250997 chr9:106856677 SMC2 0.43 7.37 0.37 1.32e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs7927592 0.763 rs10896340 chr11:68312645 A/G cg16797656 chr11:68205561 LRP5 -0.51 -8.96 -0.44 2.14e-17 Total body bone mineral density; LIHC cis rs10454142 0.700 rs72820427 chr2:48585506 C/T cg15846641 chr2:48541264 FOXN2 0.48 5.91 0.3 8.49e-9 Sex hormone-binding globulin levels; LIHC cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 6.16 0.32 2.08e-9 Schizophrenia; LIHC cis rs11190604 1.000 rs2489053 chr10:102353341 A/G cg07080220 chr10:102295463 HIF1AN 0.55 7.73 0.39 1.18e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3806843 0.966 rs2563267 chr5:140136913 C/T cg26395211 chr5:140044315 WDR55 0.41 6.15 0.32 2.17e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg23758822 chr17:41437982 NA 0.94 17.86 0.69 7.08e-51 Menopause (age at onset); LIHC cis rs1728785 1.000 rs8058145 chr16:68584090 G/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs9420 0.961 rs71484468 chr11:57632799 G/C cg19752551 chr11:57585705 CTNND1 -0.5 -6.93 -0.35 2.1e-11 Schizophrenia; LIHC cis rs2839186 0.732 rs8131458 chr21:47694712 G/A cg00815214 chr21:47717953 NA -0.36 -5.85 -0.3 1.16e-8 Testicular germ cell tumor; LIHC cis rs1707322 0.717 rs3014237 chr1:46090252 A/G cg06784218 chr1:46089804 CCDC17 -0.41 -7.28 -0.37 2.26e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1728785 1.000 rs1615609 chr16:68596401 C/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.5 0.33 2.82e-10 Ulcerative colitis; LIHC cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg02931644 chr1:25747376 RHCE 0.36 7.83 0.39 6.24e-14 Erythrocyte sedimentation rate; LIHC cis rs17376456 0.825 rs17314074 chr5:93161467 T/C cg25358565 chr5:93447407 FAM172A 0.92 6.39 0.33 5.58e-10 Diabetic retinopathy; LIHC cis rs7100689 0.753 rs2185426 chr10:82120887 G/A cg00277334 chr10:82204260 NA -0.54 -6.68 -0.34 9.51e-11 Post bronchodilator FEV1; LIHC cis rs9733 0.596 rs11807058 chr1:150640475 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs2562456 0.917 rs11085463 chr19:21751302 G/T cg23367146 chr19:21773418 NA 0.39 6.22 0.32 1.49e-9 Pain; LIHC cis rs854765 0.647 rs854769 chr17:18019011 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.4 -7.53 -0.38 4.55e-13 Total body bone mineral density; LIHC cis rs611744 0.647 rs633901 chr8:109242981 G/T cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC trans rs11098499 0.754 rs12513083 chr4:120249612 A/T cg25214090 chr10:38739885 LOC399744 0.51 8.31 0.41 2.32e-15 Corneal astigmatism; LIHC cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg03517284 chr6:25882590 NA -0.65 -8.06 -0.4 1.32e-14 Intelligence (multi-trait analysis); LIHC cis rs7192750 0.586 rs4788584 chr16:71993386 A/T cg06353428 chr16:71660113 MARVELD3 0.81 9.13 0.44 6.3e-18 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs9325144 0.534 rs4882283 chr12:38710249 C/T cg26384229 chr12:38710491 ALG10B 0.58 8.06 0.4 1.29e-14 Morning vs. evening chronotype; LIHC cis rs12477438 0.520 rs2171359 chr2:99795360 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.66 0.65 4.89e-42 Chronic sinus infection; LIHC cis rs6582630 0.502 rs7312212 chr12:38274760 T/G cg26384229 chr12:38710491 ALG10B 0.82 10.54 0.5 1.12e-22 Drug-induced liver injury (flucloxacillin); LIHC cis rs9916302 0.904 rs2168785 chr17:37407135 C/T cg03013999 chr17:37608204 MED1 0.36 5.96 0.31 6.44e-9 Glomerular filtration rate (creatinine); LIHC cis rs826838 1.000 rs7953227 chr12:38946193 G/A cg13010199 chr12:38710504 ALG10B 0.6 7.53 0.38 4.63e-13 Heart rate; LIHC cis rs11098499 0.909 rs1546504 chr4:120241179 C/T cg09307838 chr4:120376055 NA 0.75 11.4 0.52 1.01e-25 Corneal astigmatism; LIHC cis rs875971 0.964 rs1643388 chr7:65844562 T/C cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs11603020 0.950 rs28362949 chr11:57371911 G/T cg19752551 chr11:57585705 CTNND1 -0.47 -5.99 -0.31 5.22e-9 Blood protein levels; LIHC cis rs17001868 0.568 rs2280790 chr22:40745181 T/C cg07138101 chr22:40742427 ADSL 0.57 6.79 0.34 4.97e-11 Mammographic density (dense area); LIHC cis rs9527 0.615 rs12248123 chr10:104735366 A/G cg15744005 chr10:104629667 AS3MT -0.29 -5.93 -0.31 7.33e-9 Arsenic metabolism; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg26338869 chr17:61819248 STRADA 0.6 8.78 0.43 8.02e-17 Prudent dietary pattern; LIHC cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg03517284 chr6:25882590 NA -0.61 -8.55 -0.42 4.09e-16 Blood metabolite levels; LIHC cis rs1577917 0.710 rs9342041 chr6:86280875 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.33 0.32 7.76e-10 Response to antipsychotic treatment; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg27088449 chr22:21272634 CRKL -0.36 -6.06 -0.31 3.54e-9 Body mass index; LIHC cis rs7107174 1.000 rs12270434 chr11:78103300 G/A cg02023728 chr11:77925099 USP35 0.4 7.52 0.38 4.84e-13 Testicular germ cell tumor; LIHC cis rs4700695 1.000 rs4700695 chr5:65411710 G/T cg21114390 chr5:65439923 SFRS12 -0.47 -5.98 -0.31 5.48e-9 Facial morphology (factor 19); LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg03721293 chr16:90014378 DEF8 0.42 7.0 0.35 1.34e-11 Skin colour saturation; LIHC cis rs10484885 0.824 rs72919982 chr6:90532600 C/G cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.69 -0.34 9.39e-11 QRS interval (sulfonylurea treatment interaction); LIHC trans rs561341 1.000 rs521919 chr17:30298039 G/T cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 8.04e-24 Hip circumference adjusted for BMI; LIHC cis rs9858542 0.953 rs6766581 chr3:49539401 T/C cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6840360 0.571 rs62327271 chr4:152535916 A/G cg22705602 chr4:152727874 NA -0.33 -6.45 -0.33 3.86e-10 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00435469 chr11:1495117 HCCA2 -0.44 -6.99 -0.35 1.41e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.528 rs2057228 chr10:38515766 T/C cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs2991971 1.000 rs2991972 chr1:46013208 C/T cg24296786 chr1:45957014 TESK2 0.51 7.32 0.37 1.75e-12 High light scatter reticulocyte count; LIHC trans rs1814175 0.630 rs1722019 chr11:49904102 G/A cg15704280 chr7:45808275 SEPT13 -0.7 -11.95 -0.54 9.7e-28 Height; LIHC cis rs3015497 0.789 rs3015502 chr14:51108427 T/C cg09863266 chr14:51125203 SAV1 -0.42 -6.77 -0.34 5.78e-11 Mean platelet volume; LIHC cis rs8180040 0.676 rs7633698 chr3:47013452 A/T cg16586182 chr3:47516702 SCAP -0.47 -8.5 -0.42 6.1e-16 Colorectal cancer; LIHC cis rs7216064 0.953 rs10445361 chr17:65962238 G/T cg12091567 chr17:66097778 LOC651250 0.64 9.11 0.44 7.11e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6723226 0.961 rs13010404 chr2:32848854 T/G cg02381751 chr2:32503542 YIPF4 -0.67 -9.83 -0.47 2.95e-20 Intelligence (multi-trait analysis); LIHC cis rs61712019 0.679 rs13025471 chr2:77729571 T/A cg11252801 chr2:77748917 LRRTM4 0.53 7.2 0.36 3.97e-12 Schizophrenia; LIHC cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg07424592 chr7:64974309 NA 0.74 8.56 0.42 3.98e-16 Diabetic kidney disease; LIHC cis rs35306767 0.855 rs35666723 chr10:867346 A/G cg10556349 chr10:835070 NA 0.67 5.85 0.3 1.13e-8 Eosinophil percentage of granulocytes; LIHC cis rs2997447 0.761 rs79778025 chr1:26449337 A/G cg19633962 chr1:26362018 EXTL1 -0.67 -6.2 -0.32 1.66e-9 QRS complex (12-leadsum); LIHC cis rs9790314 0.967 rs6762645 chr3:160948349 T/G cg04691961 chr3:161091175 C3orf57 -0.4 -6.26 -0.32 1.16e-9 Morning vs. evening chronotype; LIHC cis rs826838 0.802 rs10785619 chr12:38742897 T/A cg13010199 chr12:38710504 ALG10B 0.45 7.19 0.36 4.16e-12 Heart rate; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11792649 chr11:68664631 MRPL21 0.47 7.13 0.36 5.94e-12 Longevity; LIHC cis rs4803468 1.000 rs284655 chr19:41928765 C/T cg09537434 chr19:41945824 ATP5SL -1.03 -21.53 -0.76 1.36e-65 Height; LIHC cis rs12220238 1.000 rs10824129 chr10:76008855 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.91 0.35 2.42e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1419980 0.730 rs1558532 chr12:7735804 G/T cg10578777 chr12:7781093 NA -0.4 -5.81 -0.3 1.42e-8 HDL cholesterol levels; LIHC cis rs2066819 1.000 rs2371454 chr12:56647243 A/G cg26734620 chr12:56694298 CS -1.23 -10.54 -0.5 1.14e-22 Psoriasis vulgaris; LIHC cis rs17125944 0.686 rs7158114 chr14:53353471 C/G cg00686598 chr14:53173677 PSMC6 -0.78 -8.8 -0.43 6.93e-17 Alzheimer's disease (late onset); LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs10504229 0.679 rs60869047 chr8:58053221 G/A cg20607798 chr8:58055168 NA 0.45 6.11 0.31 2.7e-9 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.954 rs12505469 chr4:120249585 C/T cg25214090 chr10:38739885 LOC399744 0.58 9.28 0.45 2.02e-18 Corneal astigmatism; LIHC cis rs9902453 0.765 rs2250320 chr17:28128657 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs4671400 0.571 rs4672429 chr2:61495469 G/C cg14146966 chr2:61757674 XPO1 -0.36 -5.76 -0.3 1.92e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg27297192 chr10:134578999 INPP5A 0.54 7.38 0.37 1.21e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11758351 1.000 rs80313145 chr6:26194965 T/A cg03854865 chr6:26224070 HIST1H3E 0.59 6.47 0.33 3.31e-10 Gout;Renal underexcretion gout; LIHC cis rs344364 0.511 rs1742469 chr16:1950244 C/T cg26897989 chr16:1907736 C16orf73 -0.5 -6.18 -0.32 1.84e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs7089973 0.525 rs11196945 chr10:116600424 G/A cg23260525 chr10:116636907 FAM160B1 0.36 7.09 0.36 7.74e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12924588 chr2:68694517 APLF;FBXO48 -0.39 -6.04 -0.31 4.07e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs1355223 0.833 rs11032804 chr11:34680598 C/A cg11058730 chr11:34937778 PDHX;APIP -0.44 -5.97 -0.31 5.82e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC cis rs6586163 1.000 rs1926195 chr10:90753758 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.58 -8.58 -0.42 3.37e-16 Chronic lymphocytic leukemia; LIHC cis rs6831352 0.959 rs6532795 chr4:100042221 C/T cg12011299 chr4:100065546 ADH4 -0.6 -10.89 -0.51 6.72e-24 Alcohol dependence; LIHC cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg02290350 chr8:58132656 NA 0.4 8.21 0.41 4.42e-15 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.538 rs1684260 chr11:49224231 G/A cg15704280 chr7:45808275 SEPT13 0.87 15.99 0.65 2.32e-43 Height; LIHC cis rs9291683 0.525 rs12506455 chr4:10031569 T/A cg11266682 chr4:10021025 SLC2A9 0.35 7.49 0.38 5.8e-13 Bone mineral density; LIHC cis rs7582720 1.000 rs72934704 chr2:203706433 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 5.99 0.31 5.31e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2979489 0.891 rs2979508 chr8:30388444 C/T cg26383811 chr8:30366931 RBPMS -0.7 -11.43 -0.53 7.73e-26 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg00091569 chr3:40428383 ENTPD3 0.4 6.88 0.35 2.82e-11 Renal cell carcinoma; LIHC cis rs8062405 0.964 rs72793809 chr16:28832382 C/T cg07451762 chr16:28383216 NA 0.32 6.14 0.31 2.33e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg09455208 chr3:40491958 NA 0.39 7.9 0.39 3.81e-14 Renal cell carcinoma; LIHC cis rs3791406 0.500 rs11124180 chr2:240031909 C/G cg14550559 chr2:240039617 HDAC4 -0.67 -8.38 -0.41 1.36e-15 Skin aging (microtopography measurement); LIHC cis rs4919087 0.532 rs61861850 chr10:99073874 C/A cg25902810 chr10:99078978 FRAT1 -0.6 -7.1 -0.36 7.33e-12 Monocyte count; LIHC cis rs16958440 0.867 rs12386092 chr18:44672058 C/T cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs1451375 1.000 rs1966839 chr7:50627101 T/C cg14593290 chr7:50529359 DDC 0.4 6.7 0.34 8.81e-11 Malaria; LIHC cis rs7617773 0.817 rs3731513 chr3:48219537 A/G cg11946769 chr3:48343235 NME6 0.9 11.19 0.52 5.41e-25 Coronary artery disease; LIHC cis rs17125944 0.686 rs9646151 chr14:53354464 C/G cg00686598 chr14:53173677 PSMC6 -0.77 -8.64 -0.42 2.25e-16 Alzheimer's disease (late onset); LIHC cis rs11098499 1.000 rs6837898 chr4:120179154 C/T cg09307838 chr4:120376055 NA 0.73 10.81 0.5 1.27e-23 Corneal astigmatism; LIHC cis rs7246657 0.943 rs10422967 chr19:37850137 T/C cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC cis rs3892630 0.878 rs11878394 chr19:33205844 G/C cg22980127 chr19:33182716 NUDT19 1.0 12.15 0.55 1.81e-28 Red blood cell traits; LIHC cis rs2228479 0.850 rs2190808 chr16:89840856 C/T cg14709524 chr16:89940631 TCF25 0.47 5.85 0.3 1.13e-8 Skin colour saturation; LIHC cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg02891314 chr5:179741120 GFPT2 -0.42 -5.9 -0.3 8.82e-9 Height; LIHC cis rs2569991 0.891 rs361224 chr3:12922313 C/T cg22481960 chr3:13008800 IQSEC1 -0.38 -6.46 -0.33 3.69e-10 Periodontitis (DPAL); LIHC cis rs6542838 0.702 rs6739176 chr2:99536846 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.41 -6.73 -0.34 7.11e-11 Fear of minor pain; LIHC cis rs1198430 0.683 rs534417 chr1:23784965 A/G cg19827787 chr1:23763612 ASAP3 0.29 6.16 0.32 2e-9 Total cholesterol levels; LIHC cis rs6089584 0.888 rs6089623 chr20:60615759 A/G cg13770153 chr20:60521292 NA -0.34 -6.73 -0.34 7.15e-11 Body mass index; LIHC trans rs1005277 0.563 rs2505216 chr10:38482830 T/C cg23533926 chr12:111358616 MYL2 -0.32 -6.12 -0.31 2.61e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1957429 0.808 rs11628910 chr14:65332392 A/G cg23373153 chr14:65346875 NA 0.78 10.9 0.51 6.05e-24 Pediatric areal bone mineral density (radius); LIHC cis rs3770081 1.000 rs60649958 chr2:86283000 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.44 6.03 0.31 4.36e-9 Facial emotion recognition (sad faces); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11790551 chr10:134593345 INPP5A -0.39 -6.12 -0.31 2.57e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 0.723 rs4788077 chr16:28569764 G/C cg16576597 chr16:28551801 NUPR1 0.47 7.08 0.36 8.16e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs763121 0.853 rs5750649 chr22:39036769 T/C cg06022373 chr22:39101656 GTPBP1 0.75 15.23 0.64 2.5e-40 Menopause (age at onset); LIHC trans rs1459104 0.759 rs7939392 chr11:55257285 C/T cg03929089 chr4:120376271 NA 0.61 6.45 0.33 3.75e-10 Body mass index; LIHC cis rs694739 0.964 rs2510066 chr11:64052447 C/T cg02228329 chr11:64053129 BAD;GPR137 0.75 10.73 0.5 2.33e-23 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs798554 0.759 rs1636255 chr7:2892804 A/C cg19346786 chr7:2764209 NA 0.36 5.93 0.31 7.32e-9 Height; LIHC cis rs11792861 0.816 rs3763643 chr9:111695607 T/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.82 -0.35 4.1e-11 Menarche (age at onset); LIHC cis rs798554 0.679 rs2644281 chr7:2886748 A/G cg13628971 chr7:2884303 GNA12 0.6 10.21 0.48 1.5e-21 Height; LIHC cis rs7044106 0.762 rs7849566 chr9:123460769 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.25 0.52 3.36e-25 Hip circumference adjusted for BMI; LIHC cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg12310025 chr6:25882481 NA 0.57 8.33 0.41 1.98e-15 Blood metabolite levels; LIHC cis rs787274 1.000 rs4979148 chr9:115553399 C/T cg13803584 chr9:115635662 SNX30 -0.6 -6.68 -0.34 9.69e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.84 0.69 8.72e-51 Gut microbiome composition (summer); LIHC trans rs8002861 0.935 rs7318147 chr13:44445153 C/G cg17145862 chr1:211918768 LPGAT1 -0.42 -6.15 -0.32 2.22e-9 Leprosy; LIHC trans rs208520 0.754 rs12204635 chr6:66740779 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.93 0.43 2.63e-17 Exhaled nitric oxide output; LIHC cis rs637571 0.557 rs1204649 chr11:65702776 A/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 8.72 0.43 1.23e-16 Eosinophil percentage of white cells; LIHC cis rs3106136 0.527 rs2632410 chr4:95149507 A/T cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.02 -0.44 1.33e-17 Capecitabine sensitivity; LIHC cis rs3740540 0.530 rs2362505 chr10:126290739 T/G cg04949429 chr10:126290192 LHPP 0.45 7.34 0.37 1.55e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs11190604 1.000 rs1800662 chr10:102289078 C/A cg07080220 chr10:102295463 HIF1AN 0.57 8.08 0.4 1.15e-14 Palmitoleic acid (16:1n-7) levels; LIHC trans rs7613875 0.580 rs6808044 chr3:50136165 A/G cg21659725 chr3:3221576 CRBN -0.53 -7.96 -0.4 2.5e-14 Body mass index; LIHC cis rs7633770 0.786 rs1520488 chr3:46677459 C/T cg11219411 chr3:46661640 NA 0.45 8.03 0.4 1.54e-14 Coronary artery disease; LIHC cis rs2153535 0.580 rs6929206 chr6:8447961 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.66 0.53 1.1e-26 Motion sickness; LIHC cis rs11673344 0.582 rs114437741 chr19:37446281 G/C cg27390819 chr19:37464633 NA -0.53 -6.38 -0.33 5.79e-10 Obesity-related traits; LIHC cis rs7107174 1.000 rs10899467 chr11:78014057 G/T cg02023728 chr11:77925099 USP35 0.51 9.67 0.46 1.02e-19 Testicular germ cell tumor; LIHC cis rs4925386 0.808 rs1741634 chr20:60925979 A/C cg24112000 chr20:60950667 NA 0.43 6.91 0.35 2.41e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs6430585 0.527 rs7592050 chr2:136459227 C/T cg07169764 chr2:136633963 MCM6 -0.66 -8.49 -0.42 6.23e-16 Corneal structure; LIHC cis rs4713118 0.629 rs203890 chr6:28022248 T/C cg16479474 chr6:28041457 NA 0.47 7.16 0.36 4.85e-12 Parkinson's disease; LIHC cis rs12980942 0.935 rs34075897 chr19:41826598 A/G cg25627403 chr19:41769009 HNRNPUL1 0.48 5.93 0.31 7.49e-9 Coronary artery disease; LIHC cis rs1707322 1.000 rs10890350 chr1:46262378 G/A cg06784218 chr1:46089804 CCDC17 0.34 6.14 0.32 2.28e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6942756 1.000 rs17168512 chr7:128955033 A/G cg02491457 chr7:128862824 NA -0.63 -9.0 -0.44 1.58e-17 White matter hyperintensity burden; LIHC cis rs1801251 1.000 rs283475 chr2:233654381 A/C cg25237894 chr2:233734115 C2orf82 -0.56 -10.88 -0.51 6.87e-24 Coronary artery disease; LIHC cis rs77637988 0.604 rs7566239 chr2:48598882 G/A cg15846641 chr2:48541264 FOXN2 0.58 7.96 0.4 2.61e-14 Joint mobility (Beighton score); LIHC cis rs910316 0.789 rs4899552 chr14:75667921 C/A cg08847533 chr14:75593920 NEK9 -0.83 -16.81 -0.67 1.15e-46 Height; LIHC cis rs4555082 0.834 rs1473672 chr14:105721981 G/T cg10792982 chr14:105748885 BRF1 0.45 6.03 0.31 4.22e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg00750074 chr16:89608354 SPG7 0.46 7.42 0.37 9.07e-13 Multiple myeloma (IgH translocation); LIHC cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg06634786 chr22:41940651 POLR3H 0.75 7.79 0.39 7.89e-14 Vitiligo; LIHC cis rs7584330 0.666 rs1574530 chr2:238395708 A/T cg08992911 chr2:238395768 MLPH 0.49 5.89 0.3 9.14e-9 Prostate cancer; LIHC cis rs2425143 1.000 rs7267759 chr20:34257284 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.84 -0.3 1.2e-8 Blood protein levels; LIHC cis rs12291225 0.585 rs10832246 chr11:14380828 G/A cg05501817 chr11:14380813 RRAS2 -0.45 -6.28 -0.32 1.01e-9 Sense of smell; LIHC cis rs9486719 1.000 rs34236778 chr6:96884556 C/A cg06623918 chr6:96969491 KIAA0776 -0.72 -7.15 -0.36 5.19e-12 Migraine;Coronary artery disease; LIHC cis rs1018836 0.828 rs756568 chr8:91557038 G/C cg16814680 chr8:91681699 NA -0.53 -8.31 -0.41 2.26e-15 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1865760 0.713 rs2013063 chr6:25994098 C/T cg18357526 chr6:26021779 HIST1H4A 0.41 6.13 0.31 2.36e-9 Height; LIHC cis rs11122272 0.735 rs910822 chr1:231498721 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.46 0.46 5.03e-19 Hemoglobin concentration; LIHC cis rs986417 1.000 rs1262174 chr14:60887194 C/T cg27398547 chr14:60952738 C14orf39 0.65 7.49 0.38 5.75e-13 Gut microbiota (bacterial taxa); LIHC cis rs244293 0.862 rs11079146 chr17:53094122 T/C cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.47 0.37 6.77e-13 Menarche (age at onset); LIHC cis rs7772486 0.686 rs9386131 chr6:146121608 G/A cg23711669 chr6:146136114 FBXO30 0.64 11.51 0.53 3.76e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.504 rs9405393 chr6:8467432 G/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs11627756 0.957 rs12434778 chr14:103142135 G/T cg12046867 chr14:103022105 NA 0.39 5.95 0.31 6.76e-9 Mean platelet volume; LIHC cis rs2762353 0.603 rs12201071 chr6:25778055 C/T cg03517284 chr6:25882590 NA 0.48 6.42 0.33 4.5e-10 Blood metabolite levels; LIHC cis rs9790314 0.846 rs9834659 chr3:160980947 A/C cg03342759 chr3:160939853 NMD3 -0.82 -13.51 -0.59 1.31e-33 Morning vs. evening chronotype; LIHC cis rs12472274 0.618 rs12477307 chr2:239110514 G/T cg17459225 chr2:239074497 NA 0.65 10.56 0.5 9.67e-23 Phospholipid levels (plasma); LIHC cis rs919433 0.617 rs4850809 chr2:198583403 C/T cg10820045 chr2:198174542 NA -0.5 -7.71 -0.38 1.43e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11148252 0.557 rs9536223 chr13:53233194 A/T cg00495681 chr13:53174319 NA 0.69 12.19 0.55 1.21e-28 Lewy body disease; LIHC cis rs7250872 0.606 rs2289286 chr19:1822668 T/C cg18850929 chr19:1828978 REXO1 0.4 6.45 0.33 3.88e-10 Bipolar disorder; LIHC cis rs11871801 0.881 rs2071046 chr17:40689613 G/C cg14558262 chr17:40713999 COASY -0.51 -6.98 -0.35 1.56e-11 Crohn's disease; LIHC cis rs11628318 0.614 rs1190342 chr14:103100382 C/T cg23461800 chr14:103021989 NA -0.42 -5.87 -0.3 1.03e-8 Platelet count; LIHC cis rs2832191 1.000 rs2832189 chr21:30487414 C/T cg24692254 chr21:30365293 RNF160 -0.63 -11.24 -0.52 3.79e-25 Dental caries; LIHC cis rs9560113 0.573 rs61955236 chr13:112242861 G/A cg10483660 chr13:112241077 NA 0.26 6.56 0.33 2e-10 Menarche (age at onset); LIHC cis rs2425143 0.512 rs2425126 chr20:34331730 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.74 -0.43 1.1e-16 Blood protein levels; LIHC cis rs3736485 0.808 rs55982453 chr15:51951245 C/T cg08986416 chr15:51914746 DMXL2 -0.43 -6.05 -0.31 3.8e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs151997 1.000 rs152854 chr5:50223206 G/A cg06027927 chr5:50259733 NA -0.58 -7.79 -0.39 8.07e-14 Callous-unemotional behaviour; LIHC cis rs11122272 0.735 rs2011357 chr1:231480208 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.48e-18 Hemoglobin concentration; LIHC trans rs2243480 1.000 rs2533288 chr7:66056711 C/G cg10756647 chr7:56101905 PSPH 1.01 11.98 0.54 7.24e-28 Diabetic kidney disease; LIHC cis rs2067615 0.524 rs9804754 chr12:107083031 G/A cg15890332 chr12:107067104 RFX4 0.27 6.4 0.33 5e-10 Heart rate; LIHC cis rs8083850 0.637 rs2879514 chr18:50846240 T/G cg24270629 chr18:50823537 DCC 0.53 7.91 0.39 3.71e-14 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07491203 chr7:155089714 INSIG1 0.47 6.29 0.32 9.8e-10 Lung function (FEV1/FVC); LIHC cis rs7647973 1.000 rs1982861 chr3:49577665 A/G cg07636037 chr3:49044803 WDR6 0.53 6.57 0.33 1.88e-10 Menarche (age at onset); LIHC cis rs2404602 0.536 rs7163946 chr15:76766049 C/G cg03037974 chr15:76606532 NA 0.76 14.77 0.62 1.62e-38 Blood metabolite levels; LIHC cis rs903552 0.800 rs8026048 chr15:102006353 G/A cg25677261 chr15:102009856 PCSK6 -0.49 -6.73 -0.34 7.35e-11 Diabetic kidney disease; LIHC cis rs9303401 0.615 rs35288118 chr17:56600748 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.94 12.24 0.55 8.44e-29 Cognitive test performance; LIHC cis rs7937682 0.883 rs1789351 chr11:111456436 T/A cg09085632 chr11:111637200 PPP2R1B -0.9 -10.84 -0.51 1.02e-23 Primary sclerosing cholangitis; LIHC cis rs7520050 0.966 rs12561806 chr1:46396776 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.6e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7020830 0.898 rs495863 chr9:37346955 T/C cg14294708 chr9:37120828 ZCCHC7 0.96 19.67 0.73 3.65e-58 Schizophrenia; LIHC cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg02290350 chr8:58132656 NA 0.4 8.69 0.43 1.48e-16 Developmental language disorder (linguistic errors); LIHC cis rs8017423 0.935 rs11624295 chr14:90695612 T/G cg04374321 chr14:90722782 PSMC1 0.74 14.32 0.61 9.3e-37 Mortality in heart failure; LIHC cis rs6062302 0.522 rs6090475 chr20:62245397 C/A cg06363034 chr20:62225388 GMEB2 -0.45 -7.71 -0.38 1.4e-13 Glioblastoma; LIHC cis rs11711311 0.911 rs13321446 chr3:113522544 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.37 -6.43 -0.33 4.25e-10 IgG glycosylation; LIHC cis rs1707322 0.721 rs4330955 chr1:46217485 G/C cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10242455 0.702 rs112475236 chr7:99044679 A/G cg18809830 chr7:99032528 PTCD1 -0.82 -6.37 -0.33 5.95e-10 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07936541 chr2:98206095 ANKRD36B 0.46 7.05 0.36 9.71e-12 Cognitive function; LIHC cis rs9486719 0.843 rs2472876 chr6:96845723 A/G cg06623918 chr6:96969491 KIAA0776 0.69 6.69 0.34 8.95e-11 Migraine;Coronary artery disease; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg00280220 chr17:61926910 NA 0.4 6.49 0.33 2.94e-10 Prudent dietary pattern; LIHC cis rs17401966 0.838 rs11579365 chr1:10470846 G/T cg19773385 chr1:10388646 KIF1B -0.39 -6.55 -0.33 2.16e-10 Hepatocellular carcinoma; LIHC cis rs17331151 0.573 rs3755801 chr3:52865798 G/A cg04865290 chr3:52927548 TMEM110 -0.41 -6.25 -0.32 1.23e-9 Immune reponse to smallpox (secreted IL-2); LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg23517279 chr6:96025343 MANEA -0.48 -6.37 -0.33 5.97e-10 Electroencephalogram traits; LIHC cis rs826838 0.935 rs1684406 chr12:39127265 A/G cg26384229 chr12:38710491 ALG10B -0.61 -8.98 -0.44 1.87e-17 Heart rate; LIHC cis rs7589728 0.748 rs35051888 chr2:88482258 G/A cg04511125 chr2:88470314 THNSL2 0.94 10.34 0.49 5.66e-22 Plasma clusterin levels; LIHC cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg08392591 chr16:89556376 ANKRD11 0.55 8.78 0.43 7.98e-17 Multiple myeloma (IgH translocation); LIHC cis rs1003719 0.788 rs1543748 chr21:38446581 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.25 0.55 7.23e-29 Eye color traits; LIHC cis rs425277 0.606 rs262653 chr1:2090095 T/G cg03732007 chr1:2071316 PRKCZ 0.36 6.27 0.32 1.08e-9 Height; LIHC cis rs11190604 1.000 rs6584379 chr10:102224490 G/A cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6964587 1.000 rs1859113 chr7:91679887 T/C cg17063962 chr7:91808500 NA 1.01 19.37 0.72 5.94e-57 Breast cancer; LIHC cis rs2243480 1.000 rs1638734 chr7:66097539 A/C cg12463550 chr7:65579703 CRCP 0.66 6.82 0.35 4.16e-11 Diabetic kidney disease; LIHC cis rs7953249 0.791 rs10774579 chr12:121405210 T/C cg02403541 chr12:121454288 C12orf43 -0.32 -5.74 -0.3 2.06e-8 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs2842992 0.789 rs3818300 chr6:160201677 G/A cg11366901 chr6:160182831 ACAT2 0.9 15.31 0.64 1.17e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs4803468 1.000 rs8105833 chr19:41896145 G/A cg09537434 chr19:41945824 ATP5SL -0.98 -19.97 -0.73 2.24e-59 Height; LIHC trans rs6489882 0.807 rs1859333 chr12:113370966 T/C cg10175203 chr3:128143634 NA 0.38 6.19 0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC trans rs9951602 0.512 rs9946138 chr18:76654608 A/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs9858542 0.953 rs9859556 chr3:49455986 G/T cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs11098499 0.909 rs78332141 chr4:120375782 C/T cg09307838 chr4:120376055 NA 0.75 11.34 0.52 1.56e-25 Corneal astigmatism; LIHC cis rs17428076 0.793 rs3770449 chr2:172692048 C/T cg13550731 chr2:172543902 DYNC1I2 0.38 6.2 0.32 1.65e-9 Myopia; LIHC cis rs4423214 1.000 rs4944955 chr11:71167677 C/T cg05163923 chr11:71159392 DHCR7 0.86 13.38 0.59 3.95e-33 Vitamin D levels; LIHC cis rs9814567 0.964 rs4974480 chr3:134178562 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.56 -10.32 -0.49 6.61e-22 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10193935 1.000 rs13421289 chr2:42412808 T/C cg27598129 chr2:42591480 NA -0.73 -11.01 -0.51 2.42e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs12220238 1.000 rs10824101 chr10:75947438 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.71 6.7 0.34 8.36e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs6088580 0.634 rs2424992 chr20:33012060 C/T cg08999081 chr20:33150536 PIGU 0.67 13.28 0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs921968 0.643 rs1344645 chr2:219538019 A/C cg02985541 chr2:219472218 PLCD4 0.41 7.0 0.35 1.34e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7615952 0.641 rs12487875 chr3:125787224 C/A cg05084668 chr3:125655381 ALG1L -0.39 -6.01 -0.31 4.66e-9 Blood pressure (smoking interaction); LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg21747090 chr2:27597821 SNX17 -0.42 -6.33 -0.32 7.49e-10 Total body bone mineral density; LIHC cis rs9309473 1.000 rs13428235 chr2:73633430 G/A cg20560298 chr2:73613845 ALMS1 -0.59 -6.87 -0.35 3.07e-11 Metabolite levels; LIHC cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.89 0.3 8.99e-9 Aortic root size; LIHC cis rs11677370 0.574 rs12329183 chr2:3866943 G/A cg17052675 chr2:3827356 NA -0.51 -6.17 -0.32 1.91e-9 Type 2 diabetes; LIHC cis rs11583043 1.000 rs17123612 chr1:101476814 C/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.73 0.3 2.18e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs10193935 0.901 rs871045 chr2:42609431 G/C cg27598129 chr2:42591480 NA -0.73 -11.66 -0.53 1.11e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs748404 0.631 rs6493084 chr15:43647627 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.86 0.43 4.31e-17 Lung cancer; LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg04267008 chr7:1944627 MAD1L1 -0.64 -10.15 -0.48 2.45e-21 Bipolar disorder and schizophrenia; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg07133347 chr1:107600762 PRMT6 -0.45 -6.95 -0.35 1.88e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1185460 0.565 rs538478 chr11:118925341 C/T cg01677386 chr11:118938358 VPS11 0.45 6.06 0.31 3.62e-9 Coronary artery disease; LIHC cis rs7552404 1.000 rs211718 chr1:76106675 C/T cg22875332 chr1:76189707 ACADM 0.46 6.89 0.35 2.73e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9611565 0.512 rs1983576 chr22:42166486 G/A cg06634786 chr22:41940651 POLR3H 0.73 7.39 0.37 1.15e-12 Vitiligo; LIHC cis rs7208859 0.623 rs9898084 chr17:29082334 C/G cg14067834 chr17:29058358 SUZ12P 0.69 6.8 0.34 4.81e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7786877 0.508 rs11765509 chr7:100310990 T/G cg16850897 chr7:100343110 ZAN -0.45 -6.49 -0.33 2.94e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs798554 1.000 rs798559 chr7:2758341 T/C cg19717773 chr7:2847554 GNA12 -0.39 -6.16 -0.32 2.06e-9 Height; LIHC cis rs6893300 0.524 rs62404348 chr5:179146026 G/A cg14593053 chr5:179126677 CANX 0.45 8.18 0.4 5.6e-15 Resting heart rate; LIHC trans rs9929218 0.551 rs9888942 chr16:68727572 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.91 20.76 0.75 1.6e-62 Colorectal cancer; LIHC cis rs7587476 1.000 rs1542173 chr2:215657560 C/T cg04530015 chr2:215796436 ABCA12 0.41 6.5 0.33 2.85e-10 Neuroblastoma; LIHC cis rs8180040 0.739 rs11719306 chr3:47184182 G/A cg16586182 chr3:47516702 SCAP -0.5 -9.08 -0.44 9.14e-18 Colorectal cancer; LIHC cis rs6502050 0.769 rs8079122 chr17:80120427 G/T cg11859384 chr17:80120422 CCDC57 -0.42 -5.73 -0.3 2.25e-8 Life satisfaction; LIHC cis rs11190604 1.000 rs10883500 chr10:102238324 T/G cg07080220 chr10:102295463 HIF1AN 0.5 7.06 0.36 9.17e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7296418 0.517 rs73231928 chr12:123724325 T/C cg05973401 chr12:123451056 ABCB9 0.43 6.39 0.33 5.58e-10 Platelet count; LIHC cis rs61990749 0.597 rs1048147 chr14:78139988 C/A cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.67 0.38 1.81e-13 Fibroblast growth factor basic levels; LIHC cis rs801193 1.000 rs1553609 chr7:66197139 T/C cg00343986 chr7:65444356 GUSB 0.41 6.24 0.32 1.28e-9 Aortic root size; LIHC cis rs10905065 0.965 rs2890365 chr10:5773876 C/A cg11519256 chr10:5708881 ASB13 -0.46 -6.04 -0.31 4e-9 Menopause (age at onset); LIHC cis rs921968 0.643 rs535830 chr2:219372233 C/G cg18887096 chr2:219472410 PLCD4 0.38 6.54 0.33 2.21e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg00656387 chr3:40428638 ENTPD3 -0.51 -8.72 -0.43 1.24e-16 Renal cell carcinoma; LIHC cis rs1707322 0.752 rs61784798 chr1:46173481 C/T cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs933688 1.000 rs2367526 chr5:90740525 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.39 0.66 5.8e-45 Smoking behavior; LIHC cis rs2073300 1.000 rs6114137 chr20:23457264 G/A cg12062639 chr20:23401060 NAPB 0.77 9.63 0.46 1.36e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs870825 0.616 rs7668009 chr4:185641998 A/C cg04058563 chr4:185651563 MLF1IP 0.66 7.09 0.36 7.76e-12 Blood protein levels; LIHC cis rs17685 0.712 rs4732578 chr7:75721532 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.17 -0.32 1.97e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9858542 1.000 rs6770670 chr3:49686682 T/C cg21659725 chr3:3221576 CRBN -0.57 -6.34 -0.32 7.32e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs8017423 0.935 rs8012299 chr14:90715822 G/T cg04374321 chr14:90722782 PSMC1 0.74 14.57 0.62 9.4e-38 Mortality in heart failure; LIHC cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.64 -0.38 2.21e-13 Electroencephalogram traits; LIHC trans rs7246657 0.943 rs4803347 chr19:37848017 G/A cg10208301 chr11:6592745 DNHD1 0.48 6.9 0.35 2.51e-11 Coronary artery calcification; LIHC cis rs6951245 0.554 rs35126802 chr7:1134842 C/T cg22907277 chr7:1156413 C7orf50 0.86 8.15 0.4 6.97e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7584330 0.554 rs113271883 chr2:238425594 A/G cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5e-9 Prostate cancer; LIHC cis rs11098499 0.754 rs12506487 chr4:120271361 T/G cg09307838 chr4:120376055 NA 0.62 9.83 0.47 3e-20 Corneal astigmatism; LIHC cis rs16828019 0.929 rs11209734 chr1:41698074 C/T cg03962019 chr1:41807865 NA 0.5 7.32 0.37 1.84e-12 Intelligence (multi-trait analysis); LIHC cis rs992157 0.717 rs11692780 chr2:219149163 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.78 -12.21 -0.55 1.07e-28 Colorectal cancer; LIHC cis rs2073300 0.609 rs2281434 chr20:23378101 C/A cg16736954 chr20:23401023 NAPB 0.71 8.28 0.41 2.86e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs74181299 0.620 rs6546123 chr2:65303582 T/C cg05010058 chr2:65284262 CEP68 -0.38 -6.45 -0.33 3.9e-10 Pulse pressure; LIHC cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg02290350 chr8:58132656 NA 0.44 8.57 0.42 3.49e-16 Developmental language disorder (linguistic errors); LIHC cis rs16828019 0.852 rs11209545 chr1:41576357 T/G cg03387723 chr1:41708464 SCMH1 -0.42 -6.93 -0.35 2.07e-11 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.695 rs7630763 chr3:160864865 T/C cg03342759 chr3:160939853 NMD3 -0.75 -11.45 -0.53 6.55e-26 Morning vs. evening chronotype; LIHC cis rs477692 0.596 rs12247555 chr10:131370520 T/C cg05714579 chr10:131428358 MGMT -0.43 -6.86 -0.35 3.33e-11 Response to temozolomide; LIHC cis rs6502050 0.835 rs4641801 chr17:80154021 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.73 -0.3 2.16e-8 Life satisfaction; LIHC cis rs1055129 0.537 rs1135640 chr17:73949540 C/G cg08125733 chr17:73851984 WBP2 -0.55 -8.42 -0.41 1.04e-15 White matter hyperintensity burden; LIHC cis rs12286929 0.644 rs4936321 chr11:115041589 C/A cg04055981 chr11:115044050 NA 0.42 6.95 0.35 1.85e-11 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1113500 0.933 rs11185255 chr1:108633191 T/A cg06207961 chr1:108661230 NA 0.38 7.48 0.37 6.47e-13 Growth-regulated protein alpha levels; LIHC cis rs2204008 0.837 rs11181857 chr12:38413255 C/G cg26384229 chr12:38710491 ALG10B 0.58 8.12 0.4 8.75e-15 Bladder cancer; LIHC cis rs35110281 0.667 rs2250773 chr21:45087786 T/C cg04455712 chr21:45112962 RRP1B 0.54 9.35 0.45 1.21e-18 Mean corpuscular volume; LIHC trans rs1347297 0.526 rs728005 chr2:179251006 C/T cg14011486 chr1:26737247 LIN28 0.48 6.98 0.35 1.55e-11 Alzheimer disease and age of onset; LIHC cis rs5758511 0.633 rs5758689 chr22:42664972 T/G cg20195005 chr22:42527684 CYP2D6 0.31 5.76 0.3 1.9e-8 Birth weight; LIHC cis rs4638749 0.677 rs6741222 chr2:108841082 A/G cg25838818 chr2:108905173 SULT1C2 -0.4 -7.03 -0.36 1.15e-11 Blood pressure; LIHC cis rs13392177 0.637 rs61041183 chr2:219056380 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.58 7.95 0.39 2.74e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs6502050 0.604 rs9897355 chr17:80078095 G/A cg11859384 chr17:80120422 CCDC57 0.43 5.85 0.3 1.14e-8 Life satisfaction; LIHC cis rs7927592 0.956 rs11228258 chr11:68254328 A/C cg01657329 chr11:68192670 LRP5 0.48 6.25 0.32 1.25e-9 Total body bone mineral density; LIHC cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg24549020 chr5:56110836 MAP3K1 0.51 6.63 0.34 1.3100000000000001e-10 Initial pursuit acceleration; LIHC cis rs916888 0.821 rs70602 chr17:44859715 T/C cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg13607699 chr17:42295918 UBTF 0.61 11.01 0.51 2.47e-24 Total body bone mineral density; LIHC cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg05564831 chr3:52568323 NT5DC2 0.37 6.08 0.31 3.18e-9 Electroencephalogram traits; LIHC cis rs7100689 0.646 rs1340374 chr10:82129114 C/T cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs2303759 0.914 rs2288481 chr19:49878196 G/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.55 8.2 0.41 4.9e-15 Multiple sclerosis; LIHC cis rs7639513 0.767 rs6784168 chr3:12702847 T/G cg23032965 chr3:12705835 RAF1 0.65 7.73 0.39 1.2e-13 Itch intensity from mosquito bite; LIHC cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg05665937 chr4:1216051 CTBP1 0.46 6.07 0.31 3.48e-9 Obesity-related traits; LIHC cis rs66569888 0.507 rs11673736 chr2:106886935 T/C cg23109721 chr2:106886537 NA -0.59 -9.63 -0.46 1.45e-19 Facial morphology (factor 23); LIHC cis rs1555322 0.530 rs2275275 chr20:33872311 G/C cg07134254 chr20:33865797 NA 0.53 6.26 0.32 1.13e-9 Attention deficit hyperactivity disorder; LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg26338869 chr17:61819248 STRADA 0.58 8.63 0.42 2.29e-16 Prudent dietary pattern; LIHC cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg23978390 chr7:1156363 C7orf50 0.66 10.3 0.49 7.56e-22 Longevity;Endometriosis; LIHC cis rs1865760 0.516 rs9379818 chr6:26023206 G/T cg18357526 chr6:26021779 HIST1H4A 0.5 7.39 0.37 1.15e-12 Height; LIHC cis rs367615 0.512 rs246104 chr5:108700982 A/C cg17395555 chr5:108820864 NA -0.29 -6.2 -0.32 1.65e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg21724239 chr8:58056113 NA 0.49 6.36 0.33 6.38e-10 Developmental language disorder (linguistic errors); LIHC trans rs7618501 1.000 rs6802890 chr3:49832261 A/G cg21582582 chr3:182698605 DCUN1D1 0.54 7.06 0.36 9.08e-12 Intelligence (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01413005 chr1:171561022 BAT2L2 0.47 6.13 0.31 2.48e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs11630290 0.592 rs12232336 chr15:64153357 T/C cg12036633 chr15:63758958 NA 0.63 6.7 0.34 8.73e-11 Iris characteristics; LIHC cis rs240764 0.680 rs12209777 chr6:101156639 G/A cg12253828 chr6:101329408 ASCC3 -0.42 -6.46 -0.33 3.55e-10 Neuroticism; LIHC trans rs11577318 1.000 rs11577318 chr1:26601570 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.27 -0.41 2.97e-15 Granulocyte percentage of myeloid white cells; LIHC cis rs6815814 0.950 rs113465719 chr4:38808045 A/T cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC cis rs3806843 0.518 rs2563310 chr5:140015741 A/G cg09824255 chr5:140014002 CD14 0.28 5.99 0.31 5.37e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21304211 chr1:112281877 C1orf183 0.45 6.39 0.33 5.41e-10 Lung function (FEV1/FVC); LIHC cis rs3015497 1.000 rs3015495 chr14:51114703 C/T cg09863266 chr14:51125203 SAV1 -0.39 -6.3 -0.32 9.31e-10 Mean platelet volume; LIHC cis rs2067615 0.542 rs10861654 chr12:107122896 A/G cg15890332 chr12:107067104 RFX4 0.26 6.17 0.32 1.98e-9 Heart rate; LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.39 8.44 0.42 8.99e-16 Calcium levels; LIHC cis rs2439831 0.618 rs999026 chr15:43690215 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.73 10.62 0.5 5.96e-23 Lung cancer in ever smokers; LIHC cis rs2243480 0.803 rs13224048 chr7:65993766 G/A cg12463550 chr7:65579703 CRCP 0.67 6.92 0.35 2.23e-11 Diabetic kidney disease; LIHC cis rs11785400 0.793 rs4736366 chr8:143742413 C/T cg10596483 chr8:143751796 JRK 0.49 7.92 0.39 3.38e-14 Schizophrenia; LIHC cis rs2573652 1.000 rs2727196 chr15:100513529 C/T cg09918751 chr15:100517450 ADAMTS17 -0.81 -14.35 -0.61 7.14e-37 Height; LIHC trans rs3780486 0.846 rs10813950 chr9:33127640 A/G cg20290983 chr6:43655470 MRPS18A -1.15 -28.52 -0.84 2.09e-92 IgG glycosylation; LIHC cis rs10792665 0.724 rs7931613 chr11:82694032 C/T cg24227371 chr11:82718527 RAB30 -0.38 -9.51 -0.46 3.5e-19 Obesity-related traits; LIHC cis rs13394619 0.744 rs10929759 chr2:11722012 C/G cg07314298 chr2:11723111 GREB1 0.5 10.21 0.48 1.49e-21 Endometriosis; LIHC cis rs9486719 1.000 rs11152969 chr6:96908712 A/C cg06623918 chr6:96969491 KIAA0776 -0.66 -6.81 -0.35 4.32e-11 Migraine;Coronary artery disease; LIHC cis rs67478160 0.644 rs7159810 chr14:104294117 T/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.38 0.56 2.43e-29 Schizophrenia; LIHC cis rs1003719 0.708 rs8126491 chr21:38551219 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.99 -0.51 2.91e-24 Eye color traits; LIHC cis rs708547 0.836 rs1718882 chr4:57859533 C/G cg25525207 chr4:57843836 C4orf14;POLR2B -0.46 -6.89 -0.35 2.66e-11 Response to bleomycin (chromatid breaks); LIHC cis rs1691799 0.867 rs1168343 chr12:66758581 C/T cg16791601 chr12:66731901 HELB -0.54 -13.08 -0.58 5.56e-32 White blood cell count (basophil); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13099106 chr12:120525172 CCDC64 0.53 7.62 0.38 2.45e-13 Pancreatic cancer; LIHC cis rs10876993 0.928 rs1678540 chr12:58065002 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.23 -0.32 1.39e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs903552 0.800 rs8026048 chr15:102006353 G/A cg06707286 chr15:102010195 PCSK6 -0.49 -7.02 -0.35 1.19e-11 Diabetic kidney disease; LIHC trans rs11088226 0.581 rs2236430 chr21:33973408 A/G cg09050820 chr6:167586206 TCP10L2 -0.53 -9.25 -0.45 2.42e-18 Gastritis; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg04025307 chr7:1156635 C7orf50 0.57 10.05 0.48 5.41e-21 Longevity;Endometriosis; LIHC cis rs13256369 0.950 rs13248096 chr8:8577476 C/T cg18904891 chr8:8559673 CLDN23 0.58 9.45 0.46 5.55e-19 Obesity-related traits; LIHC cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg11644478 chr21:40555479 PSMG1 -0.45 -7.03 -0.36 1.16e-11 Cognitive function; LIHC cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg15921436 chr17:44337874 NA 0.65 6.53 0.33 2.33e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7584330 0.554 rs3751111 chr2:238426953 G/T cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs3806843 0.900 rs2563286 chr5:140125199 T/A cg26395211 chr5:140044315 WDR55 0.38 5.77 0.3 1.82e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7950696 1 rs7950696 chr11:47481533 T/C cg20307385 chr11:47447363 PSMC3 0.81 12.15 0.55 1.72e-28 Platelet count; LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg06497051 chr1:156261200 TMEM79 0.38 6.04 0.31 4.07e-9 Tonsillectomy; LIHC cis rs72781680 0.768 rs112139157 chr2:24150783 A/C cg08917208 chr2:24149416 ATAD2B 0.64 6.4 0.33 5.15e-10 Lymphocyte counts; LIHC cis rs9814567 1.000 rs2370641 chr3:134222161 A/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.95 -0.31 6.7e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs67311347 1.000 rs4973898 chr3:40459532 A/G cg18306943 chr3:40428807 ENTPD3 -0.36 -6.38 -0.33 5.83e-10 Renal cell carcinoma; LIHC cis rs34172651 0.606 rs7194189 chr16:24703484 G/T cg04756594 chr16:24857601 SLC5A11 -0.38 -6.27 -0.32 1.1e-9 Intelligence (multi-trait analysis); LIHC cis rs11676348 0.811 rs13027120 chr2:219020914 C/T cg00012203 chr2:219082015 ARPC2 0.57 7.81 0.39 6.9e-14 Ulcerative colitis; LIHC cis rs709400 0.633 rs7160208 chr14:103965528 G/A cg26031613 chr14:104095156 KLC1 0.72 9.13 0.44 6.05e-18 Body mass index; LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg24209194 chr3:40518798 ZNF619 -0.66 -10.12 -0.48 3.1e-21 Renal cell carcinoma; LIHC cis rs35306767 0.714 rs67205460 chr10:1090366 C/T cg26597838 chr10:835615 NA 0.77 7.44 0.37 7.95e-13 Eosinophil percentage of granulocytes; LIHC cis rs6499255 0.904 rs12447883 chr16:69722797 T/C cg15192750 chr16:69999425 NA 0.46 6.89 0.35 2.61e-11 IgE levels; LIHC cis rs5769765 1.000 rs4597652 chr22:50270570 A/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.47 0.33 3.39e-10 Mean platelet volume; LIHC cis rs7772486 0.727 rs6941429 chr6:145952283 G/A cg23711669 chr6:146136114 FBXO30 0.73 13.31 0.58 7.61e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg22974920 chr21:40686053 BRWD1 -0.42 -6.16 -0.32 2.08e-9 Cognitive function; LIHC cis rs727505 0.954 rs989177 chr7:124412886 A/G cg23710748 chr7:124431027 NA -0.34 -5.87 -0.3 1.06e-8 Lewy body disease; LIHC trans rs9929218 0.954 rs17715799 chr16:68830511 A/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.25 -0.41 3.46e-15 Colorectal cancer; LIHC cis rs3768617 0.510 rs2027075 chr1:183073266 A/G ch.1.3577855R chr1:183094577 LAMC1 0.64 11.12 0.52 1.02e-24 Fuchs's corneal dystrophy; LIHC cis rs8141529 0.732 rs11556025 chr22:29168755 T/C cg02153584 chr22:29168773 CCDC117 0.57 8.98 0.44 1.79e-17 Lymphocyte counts; LIHC cis rs9388451 0.874 rs3734634 chr6:126111800 G/A cg06289844 chr6:126071538 HEY2 0.33 5.75 0.3 1.99e-8 Brugada syndrome; LIHC cis rs1707322 1.000 rs6429588 chr1:46454058 T/G cg06784218 chr1:46089804 CCDC17 0.38 6.84 0.35 3.59e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4927850 1.000 rs7630875 chr3:195753766 A/G cg01181863 chr3:195395398 SDHAP2 -0.49 -6.36 -0.33 6.51e-10 Pancreatic cancer; LIHC cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg17372223 chr3:52568218 NT5DC2 0.35 5.87 0.3 1.05e-8 Bipolar disorder; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg23131131 chr22:24373011 LOC391322 -0.51 -7.15 -0.36 5.34e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg12386194 chr3:101231763 SENP7 0.45 6.52 0.33 2.47e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg27587257 chr11:1002310 AP2A2 0.42 6.38 0.33 5.9e-10 Immature fraction of reticulocytes; LIHC cis rs7116495 1.000 rs12291678 chr11:71570977 C/G cg26138937 chr11:71823887 C11orf51 0.7 6.64 0.34 1.25e-10 Severe influenza A (H1N1) infection; LIHC cis rs7917772 0.582 rs3936017 chr10:104354424 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs708547 0.676 rs11133470 chr4:57864926 G/T cg25525207 chr4:57843836 C4orf14;POLR2B -0.43 -6.65 -0.34 1.16e-10 Response to bleomycin (chromatid breaks); LIHC cis rs589448 0.902 rs315131 chr12:69761839 T/G cg14784868 chr12:69753453 YEATS4 0.98 22.82 0.78 1.07e-70 Cerebrospinal fluid biomarker levels; LIHC cis rs9733 0.596 rs1415148 chr1:150705755 G/A cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs9420 0.961 rs11229131 chr11:57562525 G/A cg19752551 chr11:57585705 CTNND1 -0.51 -7.08 -0.36 8.46e-12 Schizophrenia; LIHC cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.76 0.8 2.86e-78 Prudent dietary pattern; LIHC cis rs10791097 0.694 rs1054869 chr11:130742630 G/A cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9858542 0.953 rs9818590 chr3:49525096 A/G cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7412746 0.658 rs2089082 chr1:150800090 T/G cg17724175 chr1:150552817 MCL1 0.48 9.63 0.46 1.44e-19 Melanoma; LIHC cis rs5753618 0.561 rs9609254 chr22:31705942 G/A cg07713946 chr22:31675144 LIMK2 0.43 7.8 0.39 7.68e-14 Colorectal cancer; LIHC cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg03806693 chr22:41940476 POLR3H -1.07 -13.17 -0.58 2.54e-32 Vitiligo; LIHC trans rs3780486 0.846 rs7849148 chr9:33138352 A/T cg20290983 chr6:43655470 MRPS18A 1.19 30.89 0.86 5.55e-101 IgG glycosylation; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11416533 chr1:3773643 KIAA0562;DFFB -0.51 -6.39 -0.33 5.5e-10 Systolic blood pressure; LIHC cis rs16958440 0.867 rs76922914 chr18:44688454 T/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.23e-16 Sitting height ratio; LIHC cis rs9911578 1.000 rs7342903 chr17:56914588 C/G cg12560992 chr17:57184187 TRIM37 0.98 17.84 0.69 8.98e-51 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.830 rs2758352 chr6:160122921 A/G cg26839252 chr6:160211577 TCP1;MRPL18 0.35 5.96 0.31 6.33e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs11212737 0.765 rs2624143 chr11:108519363 A/G cg22776369 chr11:108536276 DDX10 0.38 6.3 0.32 9.38e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7224737 1.000 rs7224737 chr17:40289364 A/G cg00647820 chr17:40259828 DHX58 0.27 5.88 0.3 9.71e-9 Fibrinogen levels; LIHC cis rs3741404 0.609 rs687581 chr11:63871533 G/T cg05016508 chr11:63871570 FLRT1;MACROD1 -0.42 -6.55 -0.33 2.11e-10 Platelet count; LIHC cis rs9378688 1.000 rs72830182 chr6:2221488 C/T cg12303981 chr6:2244766 GMDS -0.5 -6.26 -0.32 1.12e-9 Caudate nucleus volume; LIHC cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg10295955 chr4:187884368 NA -0.96 -22.07 -0.77 1e-67 Lobe attachment (rater-scored or self-reported); LIHC cis rs34172651 0.517 rs8059004 chr16:24837905 G/A cg04756594 chr16:24857601 SLC5A11 0.61 8.99 0.44 1.68e-17 Intelligence (multi-trait analysis); LIHC cis rs4803468 1.000 rs11670757 chr19:41913431 G/T cg14132834 chr19:41945861 ATP5SL -0.43 -6.38 -0.33 5.64e-10 Height; LIHC trans rs7615952 0.932 rs13065725 chr3:125632289 C/A cg07211511 chr3:129823064 LOC729375 -0.86 -10.59 -0.5 7.32e-23 Blood pressure (smoking interaction); LIHC cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg12311346 chr5:56204834 C5orf35 -0.55 -7.25 -0.36 2.8e-12 Initial pursuit acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02172222 chr7:2274545 FTSJ2 0.43 6.8 0.35 4.72e-11 Cognitive function; LIHC cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg04317338 chr11:64019027 PLCB3 0.82 10.11 0.48 3.29e-21 Mean platelet volume; LIHC cis rs9399137 0.507 rs4451150 chr6:135279063 T/G cg24558204 chr6:135376177 HBS1L 0.59 9.93 0.47 1.43e-20 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs12497850 0.931 rs4974082 chr3:48999323 G/A cg06212747 chr3:49208901 KLHDC8B 0.58 7.48 0.37 6.53e-13 Parkinson's disease; LIHC cis rs12477438 0.501 rs7349217 chr2:99815146 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 13.49 0.59 1.46e-33 Chronic sinus infection; LIHC cis rs769267 0.930 rs1063966 chr19:19616742 G/A cg03709012 chr19:19516395 GATAD2A 1.01 17.93 0.7 3.71e-51 Tonsillectomy; LIHC cis rs2075371 0.830 rs2077671 chr7:133951204 C/T cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.68e-14 Mean platelet volume; LIHC cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg23758822 chr17:41437982 NA 0.91 16.84 0.67 8.86e-47 Menopause (age at onset); LIHC cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg05555928 chr11:63887634 MACROD1 -0.54 -7.23 -0.36 3.26e-12 Mean platelet volume; LIHC cis rs11191205 0.954 rs11191191 chr10:103800979 G/A cg15320455 chr10:103880129 LDB1 0.84 7.23 0.36 3.19e-12 Intelligence (multi-trait analysis); LIHC cis rs11608355 0.545 rs11609019 chr12:109895958 G/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg02782426 chr3:40428986 ENTPD3 0.33 6.14 0.32 2.24e-9 Renal cell carcinoma; LIHC cis rs875971 0.862 rs4368860 chr7:65608482 C/G cg18252515 chr7:66147081 NA 0.42 5.88 0.3 9.66e-9 Aortic root size; LIHC cis rs9918079 0.580 rs13120905 chr4:15612288 A/T cg04067612 chr4:15429572 C1QTNF7 0.28 5.87 0.3 1.03e-8 Obesity-related traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03955296 chr1:157107917 ETV3 -0.49 -6.41 -0.33 4.86e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7845219 0.597 rs7002058 chr8:95873993 G/C cg23172400 chr8:95962367 TP53INP1 -0.33 -7.01 -0.35 1.27e-11 Type 2 diabetes; LIHC trans rs4942242 0.640 rs17538959 chr13:44229911 T/G cg19169023 chr15:41853346 TYRO3 -0.55 -7.81 -0.39 7.2e-14 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs1865721 0.771 rs7228890 chr18:73137492 C/A cg26385618 chr18:73139727 C18orf62 -0.32 -8.58 -0.42 3.37e-16 Intelligence; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg12311636 chr6:118886798 C6orf204 -0.53 -6.22 -0.32 1.44e-9 Diastolic blood pressure; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg06047700 chr8:9413342 TNKS -0.58 -6.59 -0.34 1.68e-10 Preeclampsia; LIHC cis rs7617773 0.817 rs13100815 chr3:48287449 A/C cg11946769 chr3:48343235 NME6 0.88 10.86 0.51 8.26e-24 Coronary artery disease; LIHC cis rs6912958 0.781 rs2207146 chr6:88180641 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.36 -6.19 -0.32 1.69e-9 Monocyte percentage of white cells; LIHC cis rs1707322 0.686 rs2152078 chr1:46055600 C/T cg06784218 chr1:46089804 CCDC17 -0.4 -7.02 -0.35 1.19e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7552404 0.731 rs5745458 chr1:76345429 G/A cg10523679 chr1:76189770 ACADM -0.55 -6.44 -0.33 3.94e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2204008 0.748 rs7312204 chr12:38334909 T/C cg26384229 chr12:38710491 ALG10B 0.59 8.15 0.4 7.03e-15 Bladder cancer; LIHC cis rs1023500 0.505 rs134874 chr22:42661144 A/G cg15557168 chr22:42548783 NA -0.33 -5.79 -0.3 1.63e-8 Schizophrenia; LIHC trans rs9914544 0.564 rs9906799 chr17:18795317 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.46 -0.33 3.65e-10 Educational attainment (years of education); LIHC cis rs7208859 0.614 rs73265646 chr17:29244023 C/T cg14067834 chr17:29058358 SUZ12P 0.6 5.94 0.31 6.87e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9790314 1.000 rs4597724 chr3:160963110 A/G cg04691961 chr3:161091175 C3orf57 -0.42 -6.76 -0.34 6.12e-11 Morning vs. evening chronotype; LIHC cis rs765787 0.530 rs28524974 chr15:45543528 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.48 -0.37 6.43e-13 Uric acid levels; LIHC cis rs12980942 0.935 rs1865051 chr19:41824885 T/C cg25627403 chr19:41769009 HNRNPUL1 0.49 6.09 0.31 2.95e-9 Coronary artery disease; LIHC cis rs7903847 0.656 rs74729163 chr10:99137287 A/C cg06359132 chr10:99160096 RRP12 -0.41 -6.06 -0.31 3.55e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7592578 0.713 rs60915953 chr2:191331304 G/C cg27211696 chr2:191398769 TMEM194B -0.61 -7.8 -0.39 7.79e-14 Diastolic blood pressure; LIHC cis rs6952809 0.561 rs1548598 chr7:2438912 T/C cg23289794 chr7:2394357 EIF3B -0.63 -6.3 -0.32 8.92e-10 Multiple sclerosis; LIHC cis rs4319547 0.656 rs28730465 chr12:122863864 A/C cg23029597 chr12:123009494 RSRC2 0.51 7.31 0.37 1.91e-12 Body mass index; LIHC cis rs11585357 0.843 rs72633805 chr1:17617471 A/T cg08277548 chr1:17600880 PADI3 -0.64 -6.77 -0.34 5.59e-11 Hair shape; LIHC cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg10802521 chr3:52805072 NEK4 -0.43 -7.11 -0.36 6.88e-12 Bipolar disorder; LIHC cis rs644799 0.544 rs1150360 chr11:95512060 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.68 11.13 0.52 9.14e-25 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs7618501 0.633 rs2526748 chr3:50080439 A/G cg21659725 chr3:3221576 CRBN -0.67 -10.89 -0.51 6.46e-24 Intelligence (multi-trait analysis); LIHC trans rs2243480 0.803 rs35268390 chr7:65416536 C/G cg10756647 chr7:56101905 PSPH 1.09 13.52 0.59 1.17e-33 Diabetic kidney disease; LIHC cis rs4713118 0.955 rs9393847 chr6:27687973 G/A cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC cis rs2274273 0.653 rs1209087 chr14:55493220 C/T cg01864836 chr14:55583639 NA 0.35 5.93 0.31 7.48e-9 Protein biomarker; LIHC cis rs9916302 0.718 rs10445306 chr17:37591422 A/G cg00129232 chr17:37814104 STARD3 -0.4 -6.43 -0.33 4.4e-10 Glomerular filtration rate (creatinine); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04267164 chr19:49402096 TULP2 0.44 6.38 0.33 5.6e-10 Longevity; LIHC cis rs9914988 0.778 rs9907185 chr17:27122414 C/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs1866706 0.796 rs7927865 chr11:12853841 G/A cg25843174 chr11:12811716 TEAD1 -0.3 -6.18 -0.32 1.82e-9 Intelligence (multi-trait analysis); LIHC cis rs921968 0.643 rs832802 chr2:219386899 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.71 0.43 1.33e-16 Mean corpuscular hemoglobin concentration; LIHC trans rs7618501 0.633 rs11130234 chr3:50024758 G/T cg21659725 chr3:3221576 CRBN 0.69 11.22 0.52 4.43e-25 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg15691649 chr6:25882328 NA -0.58 -7.51 -0.38 5.24e-13 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs9505448 chr6:8459804 A/G cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs2228479 0.850 rs11640188 chr16:89807732 C/T cg06558623 chr16:89946397 TCF25 0.87 11.88 0.54 1.69e-27 Skin colour saturation; LIHC cis rs853679 0.517 rs16893666 chr6:28054707 C/T cg16479474 chr6:28041457 NA -0.45 -6.35 -0.32 6.94e-10 Depression; LIHC cis rs11690935 0.877 rs13024846 chr2:172835803 C/T cg13550731 chr2:172543902 DYNC1I2 -0.92 -16.42 -0.66 4.18e-45 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23127064 chr11:842615 TSPAN4;POLR2L 0.38 6.27 0.32 1.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2354432 0.607 rs4950385 chr1:146656292 A/G cg25205988 chr1:146714368 CHD1L 0.88 5.87 0.3 1.04e-8 Mitochondrial DNA levels; LIHC cis rs9916302 0.706 rs1877030 chr17:37740161 T/C cg07936489 chr17:37558343 FBXL20 -0.89 -11.31 -0.52 2.15e-25 Glomerular filtration rate (creatinine); LIHC cis rs16989760 1.000 rs3761430 chr22:31538002 C/T cg02055988 chr22:31671702 LIMK2 -0.49 -6.53 -0.33 2.41e-10 Age-related hearing impairment; LIHC cis rs6466055 0.604 rs1204078 chr7:104986644 A/T cg04380332 chr7:105027541 SRPK2 0.37 6.91 0.35 2.32e-11 Schizophrenia; LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg11905131 chr22:24372483 LOC391322 0.71 10.33 0.49 5.73e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg10864318 chr6:117002220 KPNA5 0.53 6.14 0.32 2.28e-9 Glycated hemoglobin levels; LIHC cis rs2404618 0.587 rs6994849 chr8:1492839 G/T cg22787604 chr8:1509810 DLGAP2 0.43 7.66 0.38 1.87e-13 Lung cancer; LIHC cis rs903552 0.800 rs12903584 chr15:101999369 G/A cg00659931 chr15:102010125 PCSK6 -0.42 -5.75 -0.3 1.94e-8 Diabetic kidney disease; LIHC cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg16405210 chr4:1374714 KIAA1530 -0.7 -10.87 -0.51 7.47e-24 Longevity; LIHC cis rs3812831 0.695 rs422149 chr13:114931086 T/G cg08824895 chr13:115047677 UPF3A 0.49 7.1 0.36 7.08e-12 Schizophrenia; LIHC cis rs1552244 0.882 rs34779351 chr3:10021801 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs12980942 0.810 rs3745295 chr19:41785282 T/G cg25627403 chr19:41769009 HNRNPUL1 0.5 6.29 0.32 9.54e-10 Coronary artery disease; LIHC cis rs8060686 0.641 rs78537727 chr16:68120606 A/G cg09835421 chr16:68378352 PRMT7 -0.49 -5.82 -0.3 1.38e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs4407350 0.729 rs9819 chr22:44889386 C/T cg11695653 chr22:44894386 LDOC1L 0.39 6.68 0.34 9.97e-11 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg11062466 chr8:58055876 NA 0.46 6.52 0.33 2.46e-10 Developmental language disorder (linguistic errors); LIHC cis rs7131987 0.650 rs11050187 chr12:29472876 T/C cg12903224 chr12:29470962 FAR2 -0.41 -6.67 -0.34 1.01e-10 QT interval; LIHC cis rs4706831 0.647 rs9350847 chr6:80889017 C/T cg08355045 chr6:80787529 NA 0.31 6.34 0.32 7.38e-10 Joint mobility (Beighton score); LIHC cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg02290350 chr8:58132656 NA 0.4 8.45 0.42 8.63e-16 Developmental language disorder (linguistic errors); LIHC cis rs3008870 0.755 rs4486425 chr1:67460791 T/C cg02640540 chr1:67518911 SLC35D1 -0.41 -6.4 -0.33 5.19e-10 Lymphocyte percentage of white cells; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg23131131 chr22:24373011 LOC391322 -0.66 -9.64 -0.46 1.29e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg02711726 chr17:80685570 FN3KRP 0.43 7.93 0.39 3.05e-14 Glycated hemoglobin levels; LIHC cis rs924607 1.000 rs2455331 chr5:643593 T/C cg04221910 chr5:616842 CEP72 0.42 7.55 0.38 3.91e-13 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs17685 0.712 rs4552844 chr7:75718095 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4450131 0.522 rs3781451 chr10:126355477 G/A cg20435097 chr10:126320824 FAM53B 0.67 12.28 0.55 5.98e-29 White blood cell count (basophil); LIHC cis rs2404602 0.583 rs2176623 chr15:76568579 C/T cg03037974 chr15:76606532 NA 0.89 22.87 0.78 6.64e-71 Blood metabolite levels; LIHC cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg07061783 chr6:25882402 NA -0.44 -6.16 -0.32 2.06e-9 Blood metabolite levels; LIHC cis rs5770917 1.000 rs1557503 chr22:51013072 G/A cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.43 -6.25 -0.32 1.23e-9 Narcolepsy; LIHC cis rs12701220 0.522 rs1881116 chr7:1053958 C/T cg26769984 chr7:1090371 C7orf50 0.46 6.26 0.32 1.19e-9 Bronchopulmonary dysplasia; LIHC cis rs4478037 0.822 rs77355992 chr3:33107518 T/C cg27203090 chr3:33138513 GLB1;TMPPE -0.53 -6.14 -0.32 2.31e-9 Major depressive disorder; LIHC cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg22907277 chr7:1156413 C7orf50 0.43 6.34 0.32 7.25e-10 Longevity;Endometriosis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09709592 chr16:2580833 AMDHD2;CEMP1 -0.39 -6.38 -0.33 5.73e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6762 0.748 rs1130719 chr11:838760 T/A cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.58 -0.46 2.07e-19 Mean platelet volume; LIHC cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg24675658 chr1:53192096 ZYG11B 0.63 10.23 0.48 1.29e-21 Monocyte count; LIHC cis rs4803468 0.934 rs8103531 chr19:41891974 C/T cg14132834 chr19:41945861 ATP5SL -0.39 -5.72 -0.3 2.39e-8 Height; LIHC cis rs9393777 0.588 rs3799380 chr6:26467182 C/T cg12826209 chr6:26865740 GUSBL1 -0.65 -8.44 -0.42 9.29e-16 Intelligence (multi-trait analysis); LIHC cis rs965469 0.895 rs6051839 chr20:3391191 C/T cg25506879 chr20:3388711 C20orf194 0.51 5.85 0.3 1.18e-8 IFN-related cytopenia; LIHC cis rs7208859 0.623 rs9916725 chr17:29107471 A/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg11494091 chr17:61959527 GH2 0.44 7.92 0.39 3.47e-14 Prudent dietary pattern; LIHC cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg07061783 chr6:25882402 NA 0.67 8.89 0.43 3.69e-17 Blood metabolite levels; LIHC cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.44 0.33 3.98e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7408868 1.000 rs7247835 chr19:15262844 A/G cg14696996 chr19:15285081 NOTCH3 0.49 6.43 0.33 4.27e-10 Pulse pressure; LIHC cis rs965469 0.779 rs6051710 chr20:3264661 T/C cg25506879 chr20:3388711 C20orf194 -0.54 -6.63 -0.34 1.33e-10 IFN-related cytopenia; LIHC cis rs6435862 0.593 rs34732883 chr2:215674371 C/T cg04530015 chr2:215796436 ABCA12 0.49 9.07 0.44 9.83e-18 Neuroblastoma (high-risk); LIHC cis rs2204008 0.805 rs12146846 chr12:37985847 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs35883536 0.875 rs1970227 chr1:101140723 G/A cg14515779 chr1:101123966 NA 0.66 12.8 0.57 6.44e-31 Monocyte count; LIHC trans rs11098499 0.821 rs10032151 chr4:120391628 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.77 0.47 4.61e-20 Corneal astigmatism; LIHC cis rs2361718 0.501 rs8065486 chr17:78138196 A/G cg09238746 chr17:78121135 EIF4A3 0.73 11.74 0.54 5.87e-27 Yeast infection; LIHC cis rs11711311 1.000 rs2305546 chr3:113503354 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.18 -0.36 4.28e-12 IgG glycosylation; LIHC cis rs2522056 0.808 rs1016988 chr5:131744574 T/C cg24060327 chr5:131705240 SLC22A5 0.63 8.64 0.42 2.25e-16 Lymphocyte counts;Fibrinogen; LIHC trans rs2243480 1.000 rs7456042 chr7:65299778 T/C cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs3892630 0.588 rs7248798 chr19:33303684 G/T cg22980127 chr19:33182716 NUDT19 1.01 13.18 0.58 2.34e-32 Red blood cell traits; LIHC cis rs155076 1.000 rs658244 chr13:21850976 T/C cg14456004 chr13:21872349 NA -1.14 -12.59 -0.56 3.94e-30 White matter hyperintensity burden; LIHC cis rs1707322 0.655 rs3014240 chr1:46089225 C/G cg24296786 chr1:45957014 TESK2 0.41 5.94 0.31 7.15e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10751667 0.600 rs10794342 chr11:924904 C/T ch.11.42038R chr11:967971 AP2A2 0.52 9.47 0.46 4.71e-19 Alzheimer's disease (late onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00850501 chr19:14530371 DDX39 0.5 6.47 0.33 3.32e-10 Lung function (FEV1/FVC); LIHC cis rs7223966 1.000 rs9912904 chr17:61763534 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.57 0.33 1.83e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.54e-18 Bipolar disorder; LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg18306943 chr3:40428807 ENTPD3 0.41 7.0 0.35 1.32e-11 Renal cell carcinoma; LIHC cis rs892961 0.867 rs312909 chr17:75413954 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.41 0.59 3.07e-33 Airflow obstruction; LIHC cis rs2230307 0.536 rs700533 chr1:100483822 A/G cg24955406 chr1:100503596 HIAT1 0.62 6.15 0.32 2.14e-9 Carotid intima media thickness; LIHC cis rs12477438 0.834 rs10179043 chr2:99687490 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.82 -10.52 -0.49 1.29e-22 Chronic sinus infection; LIHC cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg08219700 chr8:58056026 NA 0.52 6.7 0.34 8.83e-11 Developmental language disorder (linguistic errors); LIHC cis rs6546537 0.562 rs7565783 chr2:69750113 C/T cg10773587 chr2:69614142 GFPT1 -0.51 -6.77 -0.34 5.66e-11 Serum thyroid-stimulating hormone levels; LIHC cis rs9790314 0.846 rs4856714 chr3:160961824 T/C cg03342759 chr3:160939853 NMD3 -0.82 -13.51 -0.59 1.31e-33 Morning vs. evening chronotype; LIHC cis rs9814567 1.000 rs3846056 chr3:134227292 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.29 -0.55 5.27e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7534824 0.543 rs1074739 chr1:101362371 C/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.62 6.96 0.35 1.73e-11 Refractive astigmatism; LIHC cis rs992157 1.000 rs3731859 chr2:219124222 G/A cg00012203 chr2:219082015 ARPC2 0.91 15.08 0.63 9.78e-40 Colorectal cancer; LIHC cis rs3799378 0.579 rs9348715 chr6:26375642 C/G cg14345882 chr6:26364793 BTN3A2 0.39 5.79 0.3 1.61e-8 Intelligence (multi-trait analysis); LIHC cis rs10779751 0.734 rs2748878 chr1:11129434 T/C cg08854313 chr1:11322531 MTOR 0.67 10.21 0.48 1.56e-21 Body mass index; LIHC trans rs10242455 0.702 rs55927283 chr7:99057191 G/C cg09045935 chr12:6379348 NA 0.84 6.86 0.35 3.33e-11 Blood metabolite levels; LIHC cis rs7845219 0.539 rs13271644 chr8:95853948 A/G cg16049864 chr8:95962084 TP53INP1 -0.51 -8.68 -0.42 1.69e-16 Type 2 diabetes; LIHC cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg26338869 chr17:61819248 STRADA -0.43 -5.87 -0.3 1e-8 Prudent dietary pattern; LIHC cis rs4332037 0.722 rs4721140 chr7:1917635 A/T cg23422044 chr7:1970798 MAD1L1 -0.7 -10.82 -0.51 1.13e-23 Bipolar disorder; LIHC cis rs7208859 0.573 rs73277974 chr17:29189869 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17854409 1.000 rs17854409 chr20:61491494 T/C cg05147244 chr20:61493195 TCFL5 1.21 10.64 0.5 4.8e-23 Obesity-related traits; LIHC cis rs7100689 0.577 rs1143694 chr10:82040052 C/T cg00277334 chr10:82204260 NA 0.53 6.49 0.33 2.98e-10 Post bronchodilator FEV1; LIHC cis rs1949733 0.958 rs3103069 chr4:8509451 T/G cg11789530 chr4:8429930 ACOX3 -0.76 -11.36 -0.52 1.39e-25 Response to antineoplastic agents; LIHC cis rs875971 0.545 rs4718325 chr7:65680310 G/A cg11764359 chr7:65958608 NA 0.5 6.84 0.35 3.59e-11 Aortic root size; LIHC cis rs10911232 0.507 rs10911212 chr1:183024469 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.68 0.5 3.74e-23 Hypertriglyceridemia; LIHC cis rs3820068 0.553 rs7545782 chr1:15955227 G/C cg17385448 chr1:15911702 AGMAT 0.35 6.21 0.32 1.55e-9 Systolic blood pressure; LIHC cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.5 6.91 0.35 2.43e-11 Schizophrenia; LIHC cis rs6831352 0.918 rs13112176 chr4:100055825 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7615952 1.000 rs9289275 chr3:125648659 A/T cg05084668 chr3:125655381 ALG1L -0.62 -8.89 -0.43 3.51e-17 Blood pressure (smoking interaction); LIHC cis rs35110281 0.714 rs2282526 chr21:45080552 A/T cg01579765 chr21:45077557 HSF2BP -0.36 -6.57 -0.33 1.92e-10 Mean corpuscular volume; LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg07234388 chr1:156261841 TMEM79 0.52 9.37 0.45 1.04e-18 Tonsillectomy; LIHC cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.38 0.45 9.48e-19 Bipolar disorder; LIHC cis rs986417 0.818 rs2882601 chr14:61096879 A/T cg27398547 chr14:60952738 C14orf39 0.67 7.41 0.37 1.03e-12 Gut microbiota (bacterial taxa); LIHC cis rs8058578 0.775 rs8046391 chr16:30836648 G/C cg02466173 chr16:30829666 NA -0.47 -7.56 -0.38 3.83e-13 Multiple myeloma; LIHC cis rs2816062 0.786 rs2745317 chr1:18896552 G/A cg18795169 chr1:18902165 NA -0.8 -18.31 -0.7 1.14e-52 Urate levels in lean individuals; LIHC cis rs1790761 0.667 rs658768 chr11:67337808 G/A cg00290607 chr11:67383545 NA 0.38 5.77 0.3 1.77e-8 Mean corpuscular volume; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03549856 chr1:33593141 NA -0.41 -6.59 -0.34 1.67e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1639906 0.895 rs35038526 chr7:2213106 A/G cg04267008 chr7:1944627 MAD1L1 0.44 5.77 0.3 1.76e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs9828933 0.752 rs28675788 chr3:63942188 C/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.8 -10.24 -0.48 1.23e-21 Type 2 diabetes; LIHC cis rs7249142 0.562 rs10854009 chr19:19284705 A/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.37 -6.17 -0.32 1.98e-9 IgG glycosylation; LIHC cis rs6582630 0.585 rs12422588 chr12:38478675 C/T cg26384229 chr12:38710491 ALG10B -0.44 -6.18 -0.32 1.85e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs9381040 0.672 rs6458197 chr6:41144658 C/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.41 -6.68 -0.34 9.93e-11 Alzheimer's disease (late onset); LIHC trans rs1814175 0.630 rs1722019 chr11:49904102 G/A cg03929089 chr4:120376271 NA -0.59 -9.73 -0.47 6.67e-20 Height; LIHC cis rs2637030 0.559 rs256083 chr5:52893681 G/A cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.24e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs854765 0.603 rs4506967 chr17:17990474 A/C cg04398451 chr17:18023971 MYO15A -0.66 -10.94 -0.51 4.39e-24 Total body bone mineral density; LIHC cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg02290350 chr8:58132656 NA -0.45 -9.16 -0.44 4.75e-18 Developmental language disorder (linguistic errors); LIHC cis rs7264396 0.563 rs2225950 chr20:34333015 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.75 -0.43 1.02e-16 Total cholesterol levels; LIHC cis rs4665809 0.887 rs2384324 chr2:26354239 A/G cg04944784 chr2:26401820 FAM59B -0.69 -8.63 -0.42 2.36e-16 Gut microbiome composition (summer); LIHC cis rs2991971 1.000 rs606542 chr1:46013933 T/C cg03146154 chr1:46216737 IPP -0.38 -5.85 -0.3 1.13e-8 High light scatter reticulocyte count; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00069314 chr4:170542039 CLCN3 0.32 6.44 0.33 4.1e-10 Calcium levels; LIHC trans rs6461503 0.644 rs916789 chr7:20572530 A/C cg01961949 chr17:79791406 FAM195B;DYSFIP1 0.44 6.58 0.34 1.74e-10 Allergic disease (asthma, hay fever or eczema); LIHC trans rs11098499 0.954 rs35091806 chr4:120325529 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs79149102 0.579 rs6495142 chr15:75320166 C/T cg15902774 chr15:75289873 SCAMP5 0.43 6.56 0.33 2.04e-10 Lung cancer; LIHC cis rs933688 1.000 rs1035476 chr5:90745976 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.31 0.72 1.01e-56 Smoking behavior; LIHC trans rs1464321 0.901 rs7305590 chr12:103658540 T/C cg15403093 chr12:133312361 ANKLE2 0.38 6.07 0.31 3.49e-9 Body mass index; LIHC cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg19723775 chr5:179050963 HNRNPH1 -0.41 -6.34 -0.32 7.38e-10 Lung cancer; LIHC cis rs17376456 0.825 rs10072232 chr5:93398890 G/A cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC trans rs11148252 0.532 rs9536262 chr13:53303074 A/C cg18335740 chr13:41363409 SLC25A15 -0.54 -9.1 -0.44 7.57e-18 Lewy body disease; LIHC cis rs1801251 1.000 rs12990821 chr2:233617585 C/G cg08000102 chr2:233561755 GIGYF2 0.77 11.53 0.53 3.25e-26 Coronary artery disease; LIHC trans rs62103177 0.608 rs4799115 chr18:77736365 A/T cg05926928 chr17:57297772 GDPD1 -0.64 -7.12 -0.36 6.26e-12 Opioid sensitivity; LIHC cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg09323728 chr8:95962352 TP53INP1 -0.3 -6.44 -0.33 4.09e-10 Type 2 diabetes; LIHC cis rs1144333 0.655 rs5745465 chr1:76346832 A/G cg22875332 chr1:76189707 ACADM 0.39 5.74 0.3 2.13e-8 Attention function in attention deficit hyperactive disorder; LIHC cis rs8060686 0.641 rs12599880 chr16:68152035 A/G cg05110241 chr16:68378359 PRMT7 -0.6 -6.68 -0.34 9.75e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs9911578 1.000 rs304270 chr17:56802141 A/G cg12560992 chr17:57184187 TRIM37 -0.98 -17.73 -0.69 2.37e-50 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.583 rs35707798 chr15:76565026 G/C cg22467129 chr15:76604101 ETFA -0.37 -6.15 -0.32 2.22e-9 Blood metabolite levels; LIHC cis rs8067545 0.611 rs2703776 chr17:20137709 C/A cg13482628 chr17:19912719 NA -0.43 -7.0 -0.35 1.33e-11 Schizophrenia; LIHC cis rs12936587 0.535 rs8065154 chr17:17614947 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.42 7.11 0.36 6.64e-12 Hip circumference;Coronary artery disease or large artery stroke;Coronary heart disease;Coronary artery disease; LIHC cis rs9381040 0.610 rs4140579 chr6:41041752 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.3 -0.32 9.3e-10 Alzheimer's disease (late onset); LIHC cis rs1816752 0.875 rs3783076 chr13:25064457 C/T cg22771759 chr13:24902376 NA 0.3 6.18 0.32 1.8e-9 Obesity-related traits; LIHC cis rs2370759 1.000 rs76467481 chr10:32610740 T/G cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC trans rs13381277 1.000 rs28380744 chr18:74327655 G/T cg17352830 chr21:37617589 DOPEY2 -0.54 -6.24 -0.32 1.29e-9 Dental caries; LIHC cis rs9790314 0.936 rs336572 chr3:161068014 G/A cg03342759 chr3:160939853 NMD3 -0.63 -8.24 -0.41 3.67e-15 Morning vs. evening chronotype; LIHC cis rs13191362 0.935 rs116735807 chr6:163010615 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.63 5.74 0.3 2.06e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9457247 0.534 rs4710154 chr6:167394634 A/T cg23791538 chr6:167370224 RNASET2 0.75 14.39 0.61 4.87e-37 Crohn's disease; LIHC trans rs3942852 0.774 rs10838813 chr11:48186969 C/A cg15704280 chr7:45808275 SEPT13 -0.59 -8.02 -0.4 1.65e-14 Acute lymphoblastic leukemia (childhood); LIHC trans rs10506458 0.915 rs1009540 chr12:63414872 C/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.75 -10.8 -0.5 1.31e-23 Hemostatic factors and hematological phenotypes; LIHC trans rs877282 0.891 rs11595385 chr10:800539 A/G cg22713356 chr15:30763199 NA 1.38 12.73 0.57 1.14e-30 Uric acid levels; LIHC cis rs1865760 0.892 rs2328903 chr6:25935765 T/C cg17691542 chr6:26056736 HIST1H1C 0.4 6.0 0.31 4.97e-9 Height; LIHC cis rs7582720 1.000 rs72926771 chr2:203801226 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs61677309 0.964 rs113145584 chr11:118154798 G/C cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12600695 chr5:137513806 BRD8;KIF20A 0.46 6.94 0.35 1.98e-11 Cognitive function; LIHC cis rs11958404 0.860 rs72816577 chr5:157431806 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs4555082 0.834 rs2816623 chr14:105733295 G/A cg10792982 chr14:105748885 BRF1 0.5 6.56 0.33 2.05e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs2576037 0.763 rs2060418 chr18:44576535 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.48 -7.31 -0.37 1.89e-12 Personality dimensions; LIHC cis rs2153535 0.580 rs4960413 chr6:8438466 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.3e-16 Motion sickness; LIHC cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg03264133 chr6:25882463 NA -0.7 -9.13 -0.44 6.17e-18 Intelligence (multi-trait analysis); LIHC cis rs5758659 0.714 rs6002607 chr22:42496506 C/T cg19513890 chr22:42538836 CYP2D7P1 0.43 8.34 0.41 1.79e-15 Cognitive function; LIHC cis rs8067354 0.540 rs7221472 chr17:58036737 C/T cg02344993 chr17:57696989 CLTC 0.65 10.28 0.49 8.95e-22 Hemoglobin concentration; LIHC cis rs72781680 0.821 rs72796325 chr2:24134537 G/A cg08917208 chr2:24149416 ATAD2B 0.64 6.44 0.33 4.1e-10 Lymphocyte counts; LIHC cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg06453172 chr10:134556979 INPP5A -0.65 -8.23 -0.41 4.09e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8067354 0.958 rs2777889 chr17:57848006 A/G cg13753209 chr17:57696993 CLTC 0.56 8.42 0.41 1.03e-15 Hemoglobin concentration; LIHC cis rs10276381 1.000 rs10280937 chr7:28182306 T/C cg23620719 chr7:28220237 JAZF1 0.63 7.82 0.39 6.43e-14 Crohn's disease; LIHC cis rs61440199 0.818 rs57566579 chr3:20180738 T/C cg00235661 chr3:20228976 SGOL1 -0.42 -5.8 -0.3 1.52e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs9911578 1.000 rs4793950 chr17:56593111 T/C cg05425664 chr17:57184151 TRIM37 0.58 8.51 0.42 5.54e-16 Intelligence (multi-trait analysis); LIHC cis rs2439831 0.681 rs3742971 chr15:43622916 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.89 -17.21 -0.68 2.95e-48 Lung cancer in ever smokers; LIHC cis rs2721195 0.654 rs4610795 chr8:145881333 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.44 -6.6 -0.34 1.53e-10 Age at first birth; LIHC trans rs36715 1.000 rs251386 chr5:127547298 A/G cg16011800 chr17:1958478 HIC1 -0.41 -6.06 -0.31 3.56e-9 Breast cancer; LIHC cis rs7487075 0.619 rs2220727 chr12:46805069 G/A cg23829395 chr12:46796953 NA 0.36 6.29 0.32 9.45e-10 Itch intensity from mosquito bite; LIHC cis rs986417 0.748 rs12436632 chr14:61034416 T/C cg27398547 chr14:60952738 C14orf39 0.57 7.0 0.35 1.35e-11 Gut microbiota (bacterial taxa); LIHC cis rs9378688 1.000 rs2295008 chr6:2230989 G/A cg12303981 chr6:2244766 GMDS -0.49 -6.29 -0.32 9.47e-10 Caudate nucleus volume; LIHC cis rs2303745 0.544 rs6512180 chr19:17399153 C/T cg04248312 chr19:17393744 ANKLE1 -0.72 -11.75 -0.54 5.29e-27 Systemic lupus erythematosus; LIHC cis rs826838 1.000 rs826892 chr12:39100790 T/C cg26384229 chr12:38710491 ALG10B -0.57 -8.73 -0.43 1.12e-16 Heart rate; LIHC cis rs5753037 0.543 rs140119 chr22:30138149 A/T cg01021169 chr22:30184971 ASCC2 -0.32 -5.98 -0.31 5.69e-9 Type 1 diabetes; LIHC cis rs2204008 0.623 rs1607878 chr12:38376000 A/G cg26384229 chr12:38710491 ALG10B 0.58 8.13 0.4 7.83e-15 Bladder cancer; LIHC trans rs208520 0.690 rs3843513 chr6:66836797 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.29 -0.41 2.67e-15 Exhaled nitric oxide output; LIHC cis rs6952808 0.609 rs6950151 chr7:1953521 T/C cg14004847 chr7:1930337 MAD1L1 -0.55 -8.2 -0.41 4.9e-15 Bipolar disorder and schizophrenia; LIHC cis rs904251 0.523 rs2776870 chr6:37481364 C/A cg25019722 chr6:37503610 NA -0.32 -5.74 -0.3 2.07e-8 Cognitive performance; LIHC cis rs17826219 0.568 rs9898097 chr17:29072672 T/G cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Body mass index; LIHC cis rs11098499 0.789 rs1980024 chr4:120253047 C/T cg09307838 chr4:120376055 NA 0.7 10.98 0.51 3.2e-24 Corneal astigmatism; LIHC cis rs11971779 0.584 rs6962029 chr7:139034719 T/C cg07862535 chr7:139043722 LUC7L2 0.58 10.12 0.48 3.07e-21 Diisocyanate-induced asthma; LIHC cis rs950776 0.518 rs1504545 chr15:78818471 C/G cg22563815 chr15:78856949 CHRNA5 -0.34 -6.15 -0.32 2.15e-9 Sudden cardiac arrest; LIHC cis rs7408868 1.000 rs2074622 chr19:15277620 G/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.79 -0.3 1.61e-8 Pulse pressure; LIHC cis rs7647973 0.667 rs4241405 chr3:49642027 C/T cg03060546 chr3:49711283 APEH 0.61 6.88 0.35 2.89e-11 Menarche (age at onset); LIHC cis rs11792861 0.781 rs2151426 chr9:111743797 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.66 0.42 1.95e-16 Menarche (age at onset); LIHC cis rs2408955 0.521 rs7301003 chr12:48550227 A/G cg21466736 chr12:48725269 NA -0.63 -9.13 -0.44 6.16e-18 Glycated hemoglobin levels; LIHC cis rs7044106 0.718 rs1981021 chr9:123388393 T/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 7.2 0.36 3.75e-12 Hip circumference adjusted for BMI; LIHC cis rs4665809 1.000 rs6546728 chr2:26276531 G/C cg27170947 chr2:26402098 FAM59B -0.68 -8.33 -0.41 1.98e-15 Gut microbiome composition (summer); LIHC cis rs875971 0.862 rs7809814 chr7:65615397 G/A cg18252515 chr7:66147081 NA 0.42 5.84 0.3 1.24e-8 Aortic root size; LIHC cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg11890956 chr21:40555474 PSMG1 0.56 9.38 0.45 9.64e-19 Cognitive function; LIHC cis rs7072216 0.727 rs942809 chr10:100168001 G/A cg26618903 chr10:100175079 PYROXD2 -0.38 -6.11 -0.31 2.79e-9 Metabolite levels; LIHC cis rs1775715 0.707 rs2808088 chr10:32146150 A/G cg14930904 chr10:32216787 ARHGAP12 0.35 5.99 0.31 5.46e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs898097 0.756 rs56249965 chr17:80806603 C/G cg15664640 chr17:80829946 TBCD -0.76 -12.1 -0.55 2.78e-28 Breast cancer; LIHC cis rs72627509 0.638 rs12648928 chr4:57902506 C/G cg26694713 chr4:57773883 REST 0.6 7.5 0.38 5.56e-13 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 12.89 0.57 3e-31 Alzheimer's disease; LIHC cis rs4919694 0.901 rs10509763 chr10:104776391 G/A cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC trans rs1864585 0.520 rs73208793 chr8:10680785 T/C cg26278703 chr11:58910052 FAM111A 0.74 6.71 0.34 8.19e-11 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC trans rs60843830 1.000 rs2126129 chr2:212548 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.58 7.91 0.39 3.52e-14 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2153535 0.547 rs9502720 chr6:8541362 C/A cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.58e-15 Motion sickness; LIHC cis rs11758351 0.866 rs77889957 chr6:26207435 A/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.53 0.38 4.45e-13 Gout;Renal underexcretion gout; LIHC cis rs4790333 0.562 rs2447104 chr17:2257532 C/T cg02569219 chr17:2266849 SGSM2 0.42 6.28 0.32 1.05e-9 Proinsulin levels; LIHC cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg05368731 chr17:41323189 NBR1 0.67 11.0 0.51 2.59e-24 Menopause (age at onset); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg26046968 chr14:57857884 NAA30 -0.43 -6.08 -0.31 3.17e-9 Alopecia areata; LIHC cis rs9952991 0.941 rs2014857 chr18:12774326 C/T cg23598886 chr18:12777645 NA 0.47 6.44 0.33 4.01e-10 Inflammatory skin disease; LIHC cis rs66887589 0.627 rs3872807 chr4:120360251 T/A cg09307838 chr4:120376055 NA 0.48 7.35 0.37 1.44e-12 Diastolic blood pressure; LIHC cis rs875971 0.862 rs1083554 chr7:65852341 T/C cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC trans rs17685 0.753 rs1637044 chr7:75703744 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs896854 0.902 rs726816 chr8:95968413 T/G cg09323728 chr8:95962352 TP53INP1 -0.31 -6.63 -0.34 1.3e-10 Type 2 diabetes; LIHC cis rs11718455 1.000 rs9854785 chr3:44031295 A/G cg08738300 chr3:44038990 NA 0.51 8.95 0.44 2.27e-17 Coronary artery disease; LIHC cis rs4808199 0.895 rs12981405 chr19:19651577 C/T cg03709012 chr19:19516395 GATAD2A 1.04 16.33 0.66 9.63e-45 Nonalcoholic fatty liver disease; LIHC cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.13 -0.31 2.37e-9 Colorectal cancer; LIHC cis rs1577917 0.771 rs9362237 chr6:86409064 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.47 8.01 0.4 1.82e-14 Response to antipsychotic treatment; LIHC cis rs2455799 0.613 rs7642876 chr3:15883094 A/G cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.96e-13 Mean platelet volume; LIHC cis rs12928939 0.517 rs12934512 chr16:71965230 C/G cg03805757 chr16:71968109 PKD1L3 -0.93 -12.67 -0.57 2.02e-30 Post bronchodilator FEV1; LIHC cis rs4268898 0.862 rs11125549 chr2:24576240 C/T cg06627628 chr2:24431161 ITSN2 0.5 7.0 0.35 1.37e-11 Asthma; LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg11494091 chr17:61959527 GH2 -0.43 -7.75 -0.39 1.09e-13 Prudent dietary pattern; LIHC cis rs1580019 0.534 rs13237495 chr7:32560687 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.12 24.63 0.8 9.37e-78 Cognitive ability; LIHC cis rs711245 0.573 rs7570763 chr2:36800589 A/C cg09467607 chr2:36825704 FEZ2 -0.48 -7.2 -0.36 3.78e-12 Height; LIHC cis rs11711311 1.000 rs28394480 chr3:113485143 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.23 0.45 2.97e-18 IgG glycosylation; LIHC cis rs2576037 0.562 rs477826 chr18:44397649 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.86 0.51 8.19e-24 Personality dimensions; LIHC cis rs12477438 0.798 rs6759354 chr2:99632195 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.84 -0.65 9.44e-43 Chronic sinus infection; LIHC cis rs477692 0.905 rs514963 chr10:131419707 C/T cg19680672 chr10:131412579 MGMT -0.44 -6.95 -0.35 1.9e-11 Response to temozolomide; LIHC cis rs61990749 0.597 rs9323650 chr14:78150336 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.47 -7.21 -0.36 3.5e-12 Fibroblast growth factor basic levels; LIHC cis rs7250872 0.647 rs2304615 chr19:1826112 A/G cg18850929 chr19:1828978 REXO1 0.39 6.32 0.32 7.93e-10 Bipolar disorder; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05880217 chr17:79846343 THOC4 0.42 6.29 0.32 9.45e-10 Longevity; LIHC cis rs3020736 0.500 rs6519306 chr22:42501217 T/C cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs4332037 0.539 rs11982455 chr7:1911458 A/C cg23422044 chr7:1970798 MAD1L1 -0.6 -7.31 -0.37 1.93e-12 Bipolar disorder; LIHC cis rs9916302 0.851 rs7225096 chr17:37664443 T/C cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs12048904 0.505 rs11166508 chr1:101233511 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.52 -8.53 -0.42 4.94e-16 Multiple sclerosis; LIHC cis rs9486719 1.000 rs3798296 chr6:97052286 G/A cg06623918 chr6:96969491 KIAA0776 -0.65 -6.42 -0.33 4.47e-10 Migraine;Coronary artery disease; LIHC cis rs9329289 0.603 rs2458705 chr10:2541377 A/G cg15501526 chr10:2543763 NA 0.31 8.2 0.41 4.91e-15 Age-related hearing impairment; LIHC cis rs10779751 1.000 rs11121706 chr1:11302065 C/T cg08854313 chr1:11322531 MTOR 0.76 12.36 0.56 3e-29 Body mass index; LIHC cis rs11146838 1 rs11146838 chr10:39149977 A/T cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.78 -0.3 1.66e-8 Breast cancer; LIHC cis rs807029 0.577 rs7903239 chr10:102758337 G/T cg27255678 chr10:102756921 LZTS2 0.52 7.29 0.37 2.22e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs208520 0.874 rs208514 chr6:66945520 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.69 -7.59 -0.38 3.02e-13 Exhaled nitric oxide output; LIHC trans rs208515 0.525 rs12204706 chr6:66669930 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.73 -8.48 -0.42 6.97e-16 Exhaled nitric oxide levels; LIHC cis rs6964587 0.967 rs410 chr7:91557425 C/G cg17063962 chr7:91808500 NA -1.03 -19.61 -0.73 6.22e-58 Breast cancer; LIHC cis rs2976388 0.609 rs2572904 chr8:143792193 A/C cg06565975 chr8:143823917 SLURP1 0.33 6.38 0.33 5.92e-10 Urinary tract infection frequency; LIHC cis rs2191566 0.639 rs7257749 chr19:44548666 G/A cg20607764 chr19:44506953 ZNF230 -0.37 -6.22 -0.32 1.45e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs4654899 0.758 rs6688147 chr1:21335894 A/G cg08539965 chr1:21396338 EIF4G3 0.33 5.87 0.3 1.04e-8 Superior frontal gyrus grey matter volume; LIHC cis rs9916302 0.904 rs12600751 chr17:37553651 G/C cg00129232 chr17:37814104 STARD3 0.41 6.48 0.33 3.16e-10 Glomerular filtration rate (creatinine); LIHC cis rs12594515 1.000 rs56412446 chr15:45996424 A/G cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs6582630 0.513 rs11181246 chr12:38302670 C/T cg26384229 chr12:38710491 ALG10B 0.59 8.19 0.41 5.16e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs2204008 0.744 rs66474616 chr12:38461564 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.86 0.3 1.1e-8 Bladder cancer; LIHC cis rs8067545 0.750 rs3862152 chr17:19959693 C/T cg13482628 chr17:19912719 NA 0.49 8.22 0.41 4.23e-15 Schizophrenia; LIHC cis rs801193 1.000 rs10274773 chr7:66133578 G/A cg14393609 chr7:65229607 NA -0.37 -5.83 -0.3 1.27e-8 Aortic root size; LIHC cis rs9427116 0.840 rs9427113 chr1:154626477 A/G cg17218026 chr1:154582156 ADAR 0.3 5.95 0.31 6.67e-9 Blood protein levels; LIHC cis rs9473924 0.505 rs6908879 chr6:50869856 C/T cg14470998 chr6:50812995 TFAP2B 0.94 10.91 0.51 5.57e-24 Body mass index; LIHC cis rs6089829 0.962 rs6062780 chr20:61666648 T/C cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs9513627 0.915 rs4324006 chr13:100122545 A/G cg25919922 chr13:100150906 NA -0.79 -6.91 -0.35 2.37e-11 Obesity-related traits; LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg14004847 chr7:1930337 MAD1L1 -0.42 -5.91 -0.3 8.35e-9 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00587304 chr3:172468157 NA 0.49 7.3 0.37 2.03e-12 Pancreatic cancer; LIHC cis rs918629 0.530 rs3777197 chr5:95237916 T/C cg10483112 chr5:95245456 ELL2 -0.37 -6.83 -0.35 3.84e-11 IgG glycosylation; LIHC cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg27572855 chr1:25598939 RHD 0.4 8.47 0.42 7.21e-16 Erythrocyte sedimentation rate; LIHC cis rs72781680 1.000 rs56104215 chr2:24133590 T/C cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs4853036 0.904 rs12713683 chr2:70156321 G/A cg02498382 chr2:70120550 SNRNP27 -0.41 -6.51 -0.33 2.66e-10 Colorectal or endometrial cancer; LIHC cis rs743757 1.000 rs1107265 chr3:50431995 A/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.5 7.92 0.39 3.42e-14 Diastolic blood pressure; LIHC cis rs8180040 0.845 rs295441 chr3:47333295 T/A cg02527881 chr3:46936655 PTH1R -0.3 -5.89 -0.3 9.21e-9 Colorectal cancer; LIHC cis rs10791097 0.668 rs10791102 chr11:130744977 G/A cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7089973 0.604 rs11819372 chr10:116594934 A/G cg03647239 chr10:116582469 FAM160B1 0.46 6.74 0.34 6.83e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1144333 0.655 rs114383686 chr1:76325327 C/T cg10523679 chr1:76189770 ACADM 0.48 6.85 0.35 3.55e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs8044995 0.501 rs7189887 chr16:68353915 C/T cg05110241 chr16:68378359 PRMT7 -0.93 -10.59 -0.5 7.37e-23 Schizophrenia; LIHC cis rs7613875 0.578 rs2624822 chr3:50107219 T/C cg05623727 chr3:50126028 RBM5 -0.34 -5.82 -0.3 1.38e-8 Body mass index; LIHC cis rs1003719 0.680 rs2835629 chr21:38521660 A/T cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.08 -0.51 1.42e-24 Eye color traits; LIHC cis rs2153535 0.580 rs1335643 chr6:8488021 T/G cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs7395581 0.918 rs11039166 chr11:47316691 A/C cg26139080 chr11:47293733 MADD -0.5 -8.39 -0.41 1.27e-15 HDL cholesterol; LIHC cis rs12594515 0.967 rs11854477 chr15:45998345 A/C cg19682013 chr15:45996608 NA 0.39 6.61 0.34 1.5e-10 Waist circumference;Weight; LIHC cis rs13191362 0.938 rs35395472 chr6:163008493 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2115630 0.967 rs28595395 chr15:85334952 T/C cg12501888 chr15:85177176 SCAND2 -0.49 -7.66 -0.38 1.98e-13 P wave terminal force; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T ch.7.1415213R chr7:66262805 RABGEF1 0.44 6.64 0.34 1.23e-10 Systolic blood pressure; LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs17428076 0.874 rs12619041 chr2:172600716 A/C cg13550731 chr2:172543902 DYNC1I2 -0.38 -6.16 -0.32 2.1e-9 Myopia; LIHC cis rs425535 0.619 rs13128887 chr4:74821616 G/A cg02530824 chr4:74847766 PF4 -0.39 -6.26 -0.32 1.13e-9 Blood protein levels; LIHC cis rs11166927 1.000 rs13260415 chr8:140805137 A/C cg16909799 chr8:140841666 TRAPPC9 0.52 8.25 0.41 3.58e-15 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs12611088 0.602 rs6509092 chr19:44022305 A/T cg13740135 chr19:44006432 PHLDB3 -0.41 -6.22 -0.32 1.46e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs16854884 0.657 rs16854819 chr3:143736126 C/T cg06585982 chr3:143692056 C3orf58 -0.51 -6.7 -0.34 8.52e-11 Economic and political preferences (feminism/equality); LIHC cis rs4356203 0.905 rs7478986 chr11:17131249 T/C cg15432903 chr11:17409602 KCNJ11 -0.41 -6.24 -0.32 1.31e-9 Schizophrenia;Schizophrenia or bipolar disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08770590 chr10:112064742 SMNDC1 -0.44 -6.29 -0.32 9.87e-10 Cognitive function; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg25953012 chr14:50052901 RPS29 0.43 6.49 0.33 3.04e-10 Calcium levels; LIHC trans rs4322600 0.929 rs982577 chr14:88290267 C/T cg16008221 chr8:17823628 PCM1 0.43 6.31 0.32 8.83e-10 Breast cancer; LIHC cis rs367615 0.537 rs10463600 chr5:108663636 G/A cg17395555 chr5:108820864 NA 0.29 6.27 0.32 1.11e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs11718455 0.960 rs35277738 chr3:44006732 T/C cg08738300 chr3:44038990 NA 0.51 8.86 0.43 4.47e-17 Coronary artery disease; LIHC cis rs1707322 1.000 rs11211217 chr1:46348229 C/G cg03146154 chr1:46216737 IPP 0.47 7.63 0.38 2.37e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs208520 0.690 rs10944872 chr6:66708239 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.72 8.41 0.41 1.1e-15 Exhaled nitric oxide output; LIHC cis rs11663156 1.000 rs4940261 chr18:51034552 C/T cg24270629 chr18:50823537 DCC -0.47 -6.26 -0.32 1.16e-9 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg06481639 chr22:41940642 POLR3H -0.59 -6.15 -0.32 2.15e-9 Vitiligo; LIHC cis rs7937890 0.706 rs7115393 chr11:14268378 T/A cg02886208 chr11:14281011 SPON1 0.49 6.37 0.33 6.07e-10 Mitochondrial DNA levels; LIHC trans rs66887589 0.967 rs2892869 chr4:120521297 T/C cg25214090 chr10:38739885 LOC399744 -0.4 -6.6 -0.34 1.54e-10 Diastolic blood pressure; LIHC cis rs2439831 0.867 rs3809481 chr15:43662829 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 11.04 0.51 1.95e-24 Lung cancer in ever smokers; LIHC trans rs11098499 0.954 rs1480931 chr4:120395809 G/T cg25214090 chr10:38739885 LOC399744 0.56 9.3 0.45 1.73e-18 Corneal astigmatism; LIHC cis rs208520 0.690 rs12208310 chr6:66730108 G/C cg07460842 chr6:66804631 NA 0.79 9.18 0.44 4.09e-18 Exhaled nitric oxide output; LIHC cis rs3099143 1.000 rs3106375 chr15:77142243 T/C cg21673338 chr15:77095150 SCAPER -0.49 -7.57 -0.38 3.57e-13 Recalcitrant atopic dermatitis; LIHC trans rs4942242 0.663 rs9525816 chr13:44223898 A/G cg19169023 chr15:41853346 TYRO3 -0.54 -7.49 -0.38 5.92e-13 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg24642844 chr7:1081250 C7orf50 -0.91 -8.81 -0.43 6.29e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg10862848 chr6:42927986 GNMT -0.24 -5.86 -0.3 1.1e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7258465 1.000 rs8109573 chr19:18617151 G/T cg10790698 chr19:18539756 SSBP4 -0.35 -7.33 -0.37 1.67e-12 Breast cancer; LIHC cis rs7618915 0.547 rs11719685 chr3:52676065 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.46 5.85 0.3 1.12e-8 Bipolar disorder; LIHC cis rs4638749 0.677 rs4676187 chr2:108842936 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs826838 0.967 rs826856 chr12:39115434 G/A cg26384229 chr12:38710491 ALG10B -0.64 -9.46 -0.46 5.03e-19 Heart rate; LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg06873352 chr17:61820015 STRADA -0.58 -9.62 -0.46 1.53e-19 Prudent dietary pattern; LIHC cis rs10504229 0.861 rs67966192 chr8:58188172 A/C cg02290350 chr8:58132656 NA 0.41 8.72 0.43 1.22e-16 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.614 rs2007993 chr17:56590643 T/C cg25039879 chr17:56429692 SUPT4H1 0.74 8.14 0.4 7.56e-15 Cognitive test performance; LIHC cis rs9486719 0.895 rs12527021 chr6:97025496 C/T cg06623918 chr6:96969491 KIAA0776 -0.71 -7.25 -0.36 2.82e-12 Migraine;Coronary artery disease; LIHC cis rs875971 0.862 rs778720 chr7:65846275 A/C cg18252515 chr7:66147081 NA 0.45 6.42 0.33 4.54e-10 Aortic root size; LIHC cis rs9902453 0.874 rs4474741 chr17:28148117 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -11.78 -0.54 4.01e-27 Coffee consumption (cups per day); LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg23835219 chr4:1244017 CTBP1;C4orf42 -0.4 -5.74 -0.3 2.14e-8 Longevity; LIHC cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg25894440 chr7:65020034 NA 0.55 6.38 0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs56235845 0.964 rs4075958 chr5:176784512 A/G cg05207973 chr5:176823642 SLC34A1 -0.33 -5.77 -0.3 1.8e-8 Hemoglobin concentration;Hematocrit; LIHC cis rs17270561 0.666 rs9356988 chr6:25777481 G/A cg17691542 chr6:26056736 HIST1H1C 0.45 6.22 0.32 1.49e-9 Iron status biomarkers; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg14990712 chr19:4055085 ZBTB7A 0.42 6.19 0.32 1.72e-9 Alopecia areata; LIHC cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7412746 0.503 rs72704639 chr1:150798335 A/C cg18016565 chr1:150552671 MCL1 0.5 9.6 0.46 1.71e-19 Melanoma; LIHC cis rs7044106 0.762 rs10984974 chr9:123421556 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.94 0.51 4.41e-24 Hip circumference adjusted for BMI; LIHC cis rs7474896 0.526 rs1208633 chr10:38156873 A/C cg25427524 chr10:38739819 LOC399744 0.47 5.95 0.31 6.6e-9 Obesity (extreme); LIHC trans rs10411161 0.935 rs8107422 chr19:52368775 C/A cg22319618 chr22:45562946 NUP50 -0.51 -6.84 -0.35 3.76e-11 Breast cancer; LIHC cis rs61990749 0.597 rs2267758 chr14:78147429 T/C cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.67 0.38 1.81e-13 Fibroblast growth factor basic levels; LIHC cis rs523522 0.962 rs4767914 chr12:120993817 C/T cg12219531 chr12:120966889 COQ5 0.68 13.61 0.59 5.27e-34 High light scatter reticulocyte count; LIHC cis rs12887734 0.524 rs4906364 chr14:104214342 C/G cg24130564 chr14:104152367 KLC1 -0.43 -7.08 -0.36 8.07e-12 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs8180040 0.701 rs1079276 chr3:47045739 C/G cg02527881 chr3:46936655 PTH1R -0.31 -6.24 -0.32 1.29e-9 Colorectal cancer; LIHC cis rs829883 0.646 rs249836 chr12:98878342 T/C cg23471612 chr12:98897216 NA 0.31 5.94 0.31 7e-9 Colorectal adenoma (advanced); LIHC cis rs1046896 0.739 rs28459016 chr17:80741194 G/A cg02711726 chr17:80685570 FN3KRP -0.49 -9.13 -0.44 6e-18 Glycated hemoglobin levels; LIHC cis rs11605275 1.000 rs11604681 chr11:20031042 G/A cg14835545 chr11:20032148 NAV2 -0.81 -7.39 -0.37 1.11e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1904096 0.506 rs7439869 chr4:95173779 T/C cg11021082 chr4:95130006 SMARCAD1 -0.5 -9.36 -0.45 1.11e-18 Type 2 diabetes; LIHC cis rs7208859 0.673 rs11657270 chr17:29214387 A/G cg14067834 chr17:29058358 SUZ12P 0.67 6.52 0.33 2.6e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12701220 0.655 rs10241018 chr7:1144774 G/C cg16145915 chr7:1198662 ZFAND2A -0.35 -6.8 -0.35 4.56e-11 Bronchopulmonary dysplasia; LIHC cis rs8180040 0.620 rs6442055 chr3:47110722 A/G cg27129171 chr3:47204927 SETD2 0.56 9.26 0.45 2.28e-18 Colorectal cancer; LIHC cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg20607798 chr8:58055168 NA 0.49 6.19 0.32 1.73e-9 Developmental language disorder (linguistic errors); LIHC cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg02475777 chr4:1388615 CRIPAK 0.42 6.22 0.32 1.44e-9 Longevity; LIHC cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg08280861 chr8:58055591 NA 0.54 5.98 0.31 5.73e-9 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.651 rs2420596 chr7:65915983 T/C cg18252515 chr7:66147081 NA -0.41 -5.8 -0.3 1.47e-8 Aortic root size; LIHC cis rs6831352 0.734 rs2602856 chr4:100029145 C/A cg12011299 chr4:100065546 ADH4 0.55 9.89 0.47 1.82e-20 Alcohol dependence; LIHC cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg22764044 chr5:178986830 RUFY1 0.41 6.08 0.31 3.29e-9 Lung cancer; LIHC cis rs6089584 0.853 rs1746280 chr20:60577821 C/G cg23262073 chr20:60523788 NA -0.29 -5.8 -0.3 1.48e-8 Body mass index; LIHC cis rs1395 0.634 rs72817542 chr2:27526681 C/G cg02592271 chr2:27665507 KRTCAP3 -0.49 -5.89 -0.3 9.25e-9 Blood metabolite levels; LIHC trans rs2727020 0.638 rs1164668 chr11:49330627 A/C cg03929089 chr4:120376271 NA 0.8 14.05 0.6 1.02e-35 Coronary artery disease; LIHC cis rs1348850 0.519 rs10201883 chr2:178471407 T/C cg27490568 chr2:178487706 NA 1.05 11.67 0.53 1.01e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7131987 0.621 rs57803026 chr12:29497506 G/A cg16970926 chr12:29381810 FAR2 0.29 6.04 0.31 4.02e-9 QT interval; LIHC cis rs2361710 0.668 rs2304855 chr17:78118266 T/A cg09238746 chr17:78121135 EIF4A3 -0.54 -8.26 -0.41 3.19e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; LIHC cis rs9814567 0.896 rs7653807 chr3:134345724 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.59 -9.88 -0.47 2.04e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8064024 0.599 rs3185547 chr16:4931100 A/C cg08329684 chr16:4932620 PPL 0.34 5.85 0.3 1.14e-8 Cancer; LIHC cis rs3213545 0.700 rs2260445 chr12:121468863 C/A cg02403541 chr12:121454288 C12orf43 0.64 12.22 0.55 9.57e-29 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs67311347 1.000 rs2305521 chr3:40429183 A/G cg13409248 chr3:40428643 ENTPD3 0.38 6.2 0.32 1.61e-9 Renal cell carcinoma; LIHC trans rs11039798 0.588 rs7946443 chr11:48545504 G/A cg15704280 chr7:45808275 SEPT13 0.57 6.32 0.32 8.23e-10 Axial length; LIHC cis rs655641 1.000 rs635168 chr11:85771170 T/C cg09030501 chr11:85779252 PICALM -0.52 -6.1 -0.31 2.83e-9 Platelet count; LIHC cis rs35306767 0.903 rs12761424 chr10:967295 C/T cg20503657 chr10:835505 NA 0.89 10.69 0.5 3.45e-23 Eosinophil percentage of granulocytes; LIHC cis rs7119038 0.686 rs55894437 chr11:118607417 C/T cg19308663 chr11:118741387 NA 0.42 6.43 0.33 4.21e-10 Sjögren's syndrome; LIHC cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg04025307 chr7:1156635 C7orf50 0.64 11.24 0.52 3.58e-25 Longevity;Endometriosis; LIHC trans rs1814175 0.645 rs1721995 chr11:49915488 A/G cg03929089 chr4:120376271 NA -0.84 -15.86 -0.65 7.39e-43 Height; LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg04352962 chr1:209979756 IRF6 0.4 6.18 0.32 1.87e-9 Cleft lip with or without cleft palate; LIHC cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.48 0.46 4.49e-19 Electroencephalogram traits; LIHC cis rs6815814 0.768 rs2013740 chr4:38891737 A/G cg06935464 chr4:38784597 TLR10 0.41 6.71 0.34 8e-11 Breast cancer; LIHC cis rs1475911 1.000 rs2839466 chr21:43512324 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 -0.65 -9.32 -0.45 1.53e-18 IgG glycosylation; LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg03721293 chr16:90014378 DEF8 0.37 6.47 0.33 3.49e-10 Skin colour saturation; LIHC cis rs908922 0.636 rs474086 chr1:152513431 C/T cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC cis rs2574704 0.886 rs7628261 chr3:11635482 T/G cg15876825 chr3:11651881 VGLL4 -0.46 -7.39 -0.37 1.15e-12 Body mass index; LIHC cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4237845 0.788 rs6581157 chr12:58288793 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.46 6.41 0.33 4.71e-10 Intelligence (multi-trait analysis); LIHC trans rs6058796 1.000 rs6087409 chr20:31257552 A/G cg02600331 chr11:130417168 NA 0.36 7.75 0.39 1.03e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs9911578 1.000 rs12453459 chr17:56624291 C/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.73 -0.69 2.35e-50 Intelligence (multi-trait analysis); LIHC cis rs2832191 1.000 rs9984793 chr21:30486471 T/C cg08807101 chr21:30365312 RNF160 -0.59 -9.3 -0.45 1.74e-18 Dental caries; LIHC cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg16049864 chr8:95962084 TP53INP1 -0.67 -13.21 -0.58 1.83e-32 Type 2 diabetes; LIHC cis rs8058578 0.614 rs2878304 chr16:30878366 C/T cg02466173 chr16:30829666 NA 0.43 6.55 0.33 2.14e-10 Multiple myeloma; LIHC cis rs7618501 0.699 rs2681780 chr3:49897830 C/T cg21467203 chr3:49911342 NA -0.52 -9.03 -0.44 1.29e-17 Intelligence (multi-trait analysis); LIHC cis rs11628318 0.588 rs12892602 chr14:103114091 T/C cg01864069 chr14:103024347 NA 0.35 5.86 0.3 1.11e-8 Platelet count; LIHC cis rs9814567 1.000 rs17694011 chr3:134213981 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.96 -0.31 6.34e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2952156 0.876 rs2313171 chr17:37833842 T/C cg00129232 chr17:37814104 STARD3 -0.53 -10.19 -0.48 1.76e-21 Asthma; LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.61 8.74 0.43 1.08e-16 Lymphocyte counts; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg11878867 chr6:150167359 LRP11 -0.38 -6.36 -0.33 6.51e-10 Lung cancer; LIHC cis rs240764 0.559 rs9404049 chr6:101237129 C/A cg09795085 chr6:101329169 ASCC3 -0.42 -5.86 -0.3 1.09e-8 Neuroticism; LIHC cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs11585357 0.895 rs72633808 chr1:17618665 A/G cg08277548 chr1:17600880 PADI3 -0.64 -6.79 -0.34 4.83e-11 Hair shape; LIHC cis rs1799949 0.965 rs6503727 chr17:41312859 C/T cg23758822 chr17:41437982 NA 0.96 18.58 0.71 9.5e-54 Menopause (age at onset); LIHC cis rs1691799 0.831 rs6581678 chr12:66776656 A/G cg16791601 chr12:66731901 HELB -0.57 -13.79 -0.6 1.07e-34 White blood cell count (basophil); LIHC cis rs950169 0.810 rs2879976 chr15:85109578 G/A cg03959625 chr15:84868606 LOC388152 0.42 5.87 0.3 1.05e-8 Schizophrenia; LIHC cis rs11871801 0.918 rs1032070 chr17:40618251 C/T cg14558262 chr17:40713999 COASY 0.48 6.67 0.34 1.06e-10 Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19518383 chr11:64577818 MEN1 0.49 6.73 0.34 7.07e-11 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00128877 chr1:47070178 MKNK1 0.47 6.91 0.35 2.32e-11 Pancreatic cancer; LIHC cis rs9291683 0.595 rs11722930 chr4:10035454 G/A cg11266682 chr4:10021025 SLC2A9 0.35 7.45 0.37 7.45e-13 Bone mineral density; LIHC trans rs208520 0.874 rs208481 chr6:66922636 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.7 -7.79 -0.39 8.3e-14 Exhaled nitric oxide output; LIHC cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.614 rs28758251 chr17:29223312 A/T cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13108904 0.901 rs13119532 chr4:1304505 G/C cg19318889 chr4:1322082 MAEA 0.46 6.32 0.32 8.33e-10 Obesity-related traits; LIHC cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.4 0.41 1.19e-15 Platelet count; LIHC cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg12463550 chr7:65579703 CRCP 0.67 7.18 0.36 4.48e-12 Diabetic kidney disease; LIHC cis rs9359856 0.564 rs72915933 chr6:90441464 C/T cg13799429 chr6:90582589 CASP8AP2 -0.66 -6.23 -0.32 1.35e-9 Bipolar disorder; LIHC cis rs4803468 1.000 rs2241710 chr19:41912092 G/C cg09537434 chr19:41945824 ATP5SL -1.01 -21.33 -0.76 8.44e-65 Height; LIHC cis rs12200782 1.000 rs3800304 chr6:26598798 G/A cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs6546550 0.901 rs4852375 chr2:70125988 C/G cg02498382 chr2:70120550 SNRNP27 -0.41 -6.84 -0.35 3.62e-11 Prevalent atrial fibrillation; LIHC cis rs2153535 0.563 rs1796688 chr6:8536423 A/T cg23788917 chr6:8435910 SLC35B3 0.59 8.13 0.4 7.9e-15 Motion sickness; LIHC cis rs6754311 0.593 rs1438305 chr2:136502792 C/G cg17750252 chr2:136567154 LCT 0.33 5.77 0.3 1.74e-8 Mosquito bite size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24337644 chr2:234262978 DGKD 0.43 6.26 0.32 1.12e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.875 rs969694 chr6:146394655 A/G cg23711669 chr6:146136114 FBXO30 0.54 9.5 0.46 3.92e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg11890956 chr21:40555474 PSMG1 -0.48 -8.09 -0.4 1.02e-14 Menarche (age at onset); LIHC cis rs6540556 0.723 rs3765240 chr1:209918151 G/A cg05527609 chr1:210001259 C1orf107 -0.62 -8.84 -0.43 4.99e-17 Red blood cell count; LIHC cis rs6964587 0.967 rs6973896 chr7:91778465 A/G cg17063962 chr7:91808500 NA 1.06 22.36 0.77 6.65e-69 Breast cancer; LIHC cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 8.93 0.43 2.75e-17 Platelet count; LIHC cis rs9916302 0.861 rs632202 chr17:37453294 C/A cg03013999 chr17:37608204 MED1 -0.36 -6.05 -0.31 3.8e-9 Glomerular filtration rate (creatinine); LIHC cis rs875971 0.502 rs1796227 chr7:66087019 G/C cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.7 -0.34 8.48e-11 Aortic root size; LIHC cis rs9614461 0.826 rs9614649 chr22:45746097 C/A cg04014059 chr22:45813624 RIBC2 -0.49 -5.78 -0.3 1.7e-8 Tonsillectomy; LIHC cis rs10463316 0.817 rs10040628 chr5:150821027 T/G cg03212797 chr5:150827313 SLC36A1 -0.43 -6.49 -0.33 3e-10 Metabolite levels (Pyroglutamine); LIHC cis rs8064299 0.967 rs878907 chr17:72769694 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.73 12.4 0.56 1.98e-29 Monocyte count; LIHC cis rs6456156 1.000 rs6911766 chr6:167523170 T/G cg23791538 chr6:167370224 RNASET2 0.42 6.69 0.34 9.35e-11 Primary biliary cholangitis; LIHC cis rs240764 0.853 rs108422 chr6:101039279 G/C cg09795085 chr6:101329169 ASCC3 0.48 6.43 0.33 4.34e-10 Neuroticism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06451949 chr17:48942959 NA 0.42 7.13 0.36 5.87e-12 Cognitive function; LIHC cis rs919433 0.890 rs979020 chr2:198169749 T/C cg03934865 chr2:198174659 NA -0.58 -9.21 -0.45 3.48e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs600806 0.665 rs1368988 chr1:110012123 A/T cg23091122 chr1:110024289 SYPL2 -0.49 -6.72 -0.34 7.49e-11 Intelligence (multi-trait analysis); LIHC cis rs7223966 0.961 rs112709843 chr17:61836936 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 6.95 0.35 1.89e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7223966 1.000 rs8075061 chr17:61804723 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.96 0.35 1.72e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9818758 0.607 rs13068038 chr3:49294250 C/A cg07636037 chr3:49044803 WDR6 -0.81 -8.44 -0.42 9.01e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11098499 0.739 rs10031033 chr4:120151452 C/T cg09307838 chr4:120376055 NA 0.64 9.96 0.47 1.13e-20 Corneal astigmatism; LIHC cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.45e-18 Bipolar disorder; LIHC cis rs13191362 1.000 rs55847707 chr6:163003414 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg11764359 chr7:65958608 NA 0.59 6.26 0.32 1.18e-9 Diabetic kidney disease; LIHC cis rs1801251 1.000 rs2592102 chr2:233726772 G/T cg08000102 chr2:233561755 GIGYF2 -0.76 -11.48 -0.53 5.13e-26 Coronary artery disease; LIHC cis rs72781680 1.000 rs72796339 chr2:24143063 T/C cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg03517284 chr6:25882590 NA 0.55 7.74 0.39 1.1e-13 Blood metabolite levels; LIHC cis rs4906332 1.000 rs3783397 chr14:103947289 A/G cg19000871 chr14:103996768 TRMT61A -0.46 -7.97 -0.4 2.42e-14 Coronary artery disease; LIHC cis rs2073300 1.000 rs6048813 chr20:23448221 G/A cg12062639 chr20:23401060 NAPB 0.81 9.62 0.46 1.56e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9457247 0.663 rs2237274 chr6:167442995 C/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.62 -0.42 2.61e-16 Crohn's disease; LIHC cis rs8141529 0.509 rs7287124 chr22:29239157 A/G cg15103426 chr22:29168792 CCDC117 0.65 10.48 0.49 1.75e-22 Lymphocyte counts; LIHC trans rs2243480 1.000 rs1715235 chr7:65488394 T/C cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs6952808 0.743 rs10266703 chr7:1918941 C/A cg20295408 chr7:1910781 MAD1L1 -0.51 -7.24 -0.36 2.9e-12 Bipolar disorder and schizophrenia; LIHC cis rs644799 0.544 rs498553 chr11:95534441 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.68 11.0 0.51 2.59e-24 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs8180040 0.654 rs13078131 chr3:47204939 G/T cg16586182 chr3:47516702 SCAP -0.51 -9.25 -0.45 2.51e-18 Colorectal cancer; LIHC cis rs7412746 0.611 rs1889741 chr1:150869045 T/C cg17724175 chr1:150552817 MCL1 0.37 7.35 0.37 1.52e-12 Melanoma; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04786330 chr12:27091356 C12orf11;FGFR1OP2 0.42 6.18 0.32 1.86e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg19318889 chr4:1322082 MAEA -0.64 -10.17 -0.48 2.12e-21 Longevity; LIHC cis rs600806 0.888 rs3853500 chr1:109864269 T/C cg23091122 chr1:110024289 SYPL2 -0.46 -6.06 -0.31 3.63e-9 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg11764359 chr7:65958608 NA 0.56 5.96 0.31 6.14e-9 Diabetic kidney disease; LIHC trans rs17685 0.625 rs1639630 chr7:75730499 T/C cg19862616 chr7:65841803 NCRNA00174 0.92 18.56 0.71 1.05e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs965469 1.000 rs6037560 chr20:3323055 T/C cg25506879 chr20:3388711 C20orf194 -0.59 -7.06 -0.36 9.55e-12 IFN-related cytopenia; LIHC trans rs2797369 0.570 rs2813647 chr6:101582214 G/A cg04800749 chr22:50320996 CRELD2 0.35 6.1 0.31 2.92e-9 Renal function-related traits (eGRFcrea); LIHC cis rs9790314 1.000 rs456611 chr3:161097268 A/G cg03342759 chr3:160939853 NMD3 -0.69 -8.14 -0.4 7.27e-15 Morning vs. evening chronotype; LIHC cis rs7582180 0.606 rs4851299 chr2:100954191 C/A cg14675211 chr2:100938903 LONRF2 0.54 8.53 0.42 4.82e-16 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.963 rs12076580 chr1:46258159 G/A cg03146154 chr1:46216737 IPP 0.49 7.67 0.38 1.76e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6430585 0.528 rs75753154 chr2:136665711 T/C cg25344623 chr2:136566232 LCT -0.38 -6.18 -0.32 1.78e-9 Corneal structure; LIHC cis rs1443512 0.812 rs2078098 chr12:54337527 C/A cg17410650 chr12:54324560 NA -0.37 -6.73 -0.34 7.12e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs6691722 0.503 rs12135404 chr1:24704263 C/T cg18323236 chr1:24743029 NIPAL3 -0.4 -7.21 -0.36 3.57e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs263063 0.920 rs2240678 chr19:5041178 C/T cg18473234 chr19:5097819 KDM4B 0.58 7.02 0.35 1.19e-11 Periodontitis (CDC/AAP); LIHC cis rs11608355 0.545 rs11615336 chr12:109914802 C/A cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs2806561 1.000 rs2806561 chr1:23504795 C/T cg19743168 chr1:23544995 NA -0.41 -7.97 -0.4 2.34e-14 Height; LIHC cis rs8067545 0.967 rs1034904 chr17:19927699 A/G cg13482628 chr17:19912719 NA -0.4 -6.73 -0.34 7.02e-11 Schizophrenia; LIHC trans rs3960554 0.867 rs79359354 chr7:75702597 G/A cg19862616 chr7:65841803 NCRNA00174 0.62 8.8 0.43 6.96e-17 Eotaxin levels; LIHC cis rs4665809 1.000 rs6720314 chr2:26334852 G/A cg27170947 chr2:26402098 FAM59B -0.69 -8.6 -0.42 2.87e-16 Gut microbiome composition (summer); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13426544 chr11:65729012 SART1 -0.48 -7.09 -0.36 7.52e-12 Cognitive function; LIHC cis rs11229555 0.645 rs12273638 chr11:58186335 T/C cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7044106 0.791 rs12554440 chr9:123485333 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.8 13.36 0.59 4.56e-33 Hip circumference adjusted for BMI; LIHC cis rs7223966 0.921 rs6504186 chr17:61863932 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.76 0.34 5.99e-11 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs9914544 0.564 rs11868500 chr17:18770254 A/G cg21372672 chr17:16614065 CCDC144A -0.28 -6.73 -0.34 7.38e-11 Educational attainment (years of education); LIHC cis rs7772486 0.817 rs9322047 chr6:146400394 G/A cg13319975 chr6:146136371 FBXO30 -0.36 -6.03 -0.31 4.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2230307 0.536 rs6577152 chr1:100434610 A/G cg24955406 chr1:100503596 HIAT1 0.6 6.01 0.31 4.64e-9 Carotid intima media thickness; LIHC cis rs908922 0.651 rs4845442 chr1:152485545 G/A cg20991723 chr1:152506922 NA 0.5 8.43 0.41 9.96e-16 Hair morphology; LIHC cis rs3806843 1.000 rs1548699 chr5:140164918 T/C cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs10838687 0.867 rs2633082 chr11:47248050 C/G cg25783544 chr11:47291846 MADD -0.5 -6.53 -0.33 2.36e-10 Proinsulin levels; LIHC trans rs1814175 0.645 rs7123448 chr11:49764865 T/G cg03929089 chr4:120376271 NA -0.83 -15.78 -0.65 1.52e-42 Height; LIHC cis rs11212260 0.655 rs75147935 chr11:107289379 G/A cg25435332 chr11:107328525 CWF19L2 0.8 8.13 0.4 7.75e-15 IgG glycosylation; LIHC cis rs4272321 1 rs4272321 chr7:157951835 A/G cg05195085 chr7:157951403 PTPRN2 0.22 6.46 0.33 3.54e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.72 0.39 1.27e-13 Prudent dietary pattern; LIHC cis rs950776 0.518 rs12916999 chr15:78826912 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs4845570 1.000 rs6659705 chr1:151769750 T/C cg07092448 chr1:151763213 TDRKH -0.68 -7.34 -0.37 1.55e-12 Coronary artery disease; LIHC cis rs9790314 0.589 rs1447618 chr3:160610438 C/T cg03342759 chr3:160939853 NMD3 0.57 7.39 0.37 1.13e-12 Morning vs. evening chronotype; LIHC cis rs7131987 0.650 rs6487808 chr12:29463359 C/T cg00204748 chr12:29376779 FAR2 -0.39 -7.52 -0.38 5.02e-13 QT interval; LIHC cis rs12744310 1.000 rs34315814 chr1:41769172 T/C cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9914988 0.943 rs11652272 chr17:27167973 C/G cg07195577 chr17:27052828 TLCD1 0.43 5.76 0.3 1.85e-8 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs3857067 0.806 rs6857967 chr4:95112303 C/T cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.73 -0.39 1.24e-13 QT interval; LIHC cis rs2574704 0.816 rs2443724 chr3:11655351 C/G cg15876825 chr3:11651881 VGLL4 -0.49 -7.9 -0.39 3.87e-14 Body mass index; LIHC cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg13395646 chr4:1353034 KIAA1530 -0.47 -7.78 -0.39 8.83e-14 Obesity-related traits; LIHC trans rs7714584 1.000 rs11951694 chr5:150254338 G/A cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs2204008 0.870 rs12369578 chr12:38444227 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.5 0.42 5.93e-16 Bladder cancer; LIHC cis rs6066825 0.627 rs6012497 chr20:47228591 C/T cg18078177 chr20:47281410 PREX1 0.48 7.85 0.39 5.23e-14 Colorectal cancer; LIHC cis rs7937890 0.904 rs11023169 chr11:14290985 C/A cg02886208 chr11:14281011 SPON1 0.61 9.02 0.44 1.39e-17 Mitochondrial DNA levels; LIHC cis rs1005277 0.522 rs289649 chr10:37975384 T/C cg00409905 chr10:38381863 ZNF37A -0.57 -9.96 -0.47 1.1e-20 Extrinsic epigenetic age acceleration; LIHC cis rs1559088 0.901 rs7249983 chr19:33598851 C/A cg27124370 chr19:33622961 WDR88 0.52 7.99 0.4 2.05e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1371867 0.875 rs1125706 chr8:101326739 T/A cg06636551 chr8:101224915 SPAG1 -0.49 -8.92 -0.43 2.79e-17 Atrioventricular conduction; LIHC trans rs10242455 0.702 rs73403247 chr7:99088730 G/A cg09045935 chr12:6379348 NA 0.84 6.92 0.35 2.28e-11 Blood metabolite levels; LIHC trans rs11039798 1.000 rs11039978 chr11:48760237 A/G cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC trans rs60843830 1.000 rs56167434 chr2:282137 G/C cg11347411 chr7:150020925 ACTR3C;LRRC61 0.67 9.55 0.46 2.59e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs875971 0.502 rs11769702 chr7:65720516 A/C cg11764359 chr7:65958608 NA 0.58 8.04 0.4 1.46e-14 Aortic root size; LIHC cis rs17818399 0.510 rs12105801 chr2:46799343 C/G cg02822958 chr2:46747628 ATP6V1E2 0.42 6.84 0.35 3.68e-11 Height; LIHC cis rs2239547 0.657 rs12496077 chr3:52886241 G/A cg11645453 chr3:52864694 ITIH4 0.36 9.26 0.45 2.27e-18 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21262094 chr8:56986557 SNORD54;RPS20 0.43 6.18 0.32 1.79e-9 Cognitive function; LIHC cis rs637571 0.522 rs28578718 chr11:65748400 C/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.2 0.45 3.59e-18 Eosinophil percentage of white cells; LIHC cis rs1707322 0.752 rs7529699 chr1:46134634 C/T cg03146154 chr1:46216737 IPP 0.57 9.89 0.47 1.96e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs225245 0.817 rs2301730 chr17:33998683 A/G cg05299278 chr17:33885742 SLFN14 0.24 6.44 0.33 4.09e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs1401999 1.000 rs7632670 chr3:183713877 A/G cg05044414 chr3:183734942 ABCC5 0.33 5.99 0.31 5.24e-9 Anterior chamber depth; LIHC cis rs17001868 0.568 rs9607699 chr22:40737036 G/A cg07138101 chr22:40742427 ADSL 0.54 6.4 0.33 5.03e-10 Mammographic density (dense area); LIHC cis rs694739 0.687 rs11231771 chr11:64140642 T/G cg23796481 chr11:64053134 BAD;GPR137 0.46 6.15 0.32 2.11e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs35110281 0.565 rs7278003 chr21:44966069 T/C cg04455712 chr21:45112962 RRP1B 0.42 6.97 0.35 1.62e-11 Mean corpuscular volume; LIHC cis rs10463316 1.000 rs10463316 chr5:150746034 A/G cg03212797 chr5:150827313 SLC36A1 -0.4 -6.16 -0.32 2.03e-9 Metabolite levels (Pyroglutamine); LIHC cis rs12477438 0.765 rs28648058 chr2:99696417 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.66 -0.5 4.19e-23 Chronic sinus infection; LIHC cis rs722599 0.683 rs7145246 chr14:75242394 A/T cg08847533 chr14:75593920 NEK9 -0.55 -8.37 -0.41 1.55e-15 IgG glycosylation; LIHC cis rs9682041 0.627 rs4955722 chr3:170102959 G/T cg11886554 chr3:170076028 SKIL 0.63 5.84 0.3 1.23e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs2242116 0.796 rs7623898 chr3:46974172 C/T cg02527881 chr3:46936655 PTH1R 0.45 9.1 0.44 7.49e-18 Birth weight; LIHC cis rs875971 0.895 rs778700 chr7:65866450 C/T cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs3749237 0.595 rs11130196 chr3:49490149 A/C cg07636037 chr3:49044803 WDR6 0.53 8.12 0.4 8.59e-15 Resting heart rate; LIHC cis rs941408 1.000 rs1076447 chr19:2792128 C/G cg06609049 chr19:2785107 THOP1 0.55 9.64 0.46 1.32e-19 Total cholesterol levels; LIHC cis rs4718428 0.705 rs4717328 chr7:66352665 T/C cg18252515 chr7:66147081 NA -0.68 -9.28 -0.45 1.97e-18 Corneal structure; LIHC trans rs1814175 0.653 rs10839480 chr11:50034556 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.11 -0.78 7.6e-72 Height; LIHC cis rs3736485 0.966 rs7173880 chr15:51785433 C/A cg08986416 chr15:51914746 DMXL2 -0.41 -6.11 -0.31 2.7e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs875971 0.862 rs10224872 chr7:65759773 T/A cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.03e-40 Aortic root size; LIHC cis rs4788570 0.527 rs72791971 chr16:71477297 C/G cg06353428 chr16:71660113 MARVELD3 -1.18 -10.15 -0.48 2.42e-21 Intelligence (multi-trait analysis); LIHC cis rs7107174 1.000 rs10899485 chr11:78072383 C/T cg02023728 chr11:77925099 USP35 -0.43 -8.34 -0.41 1.88e-15 Testicular germ cell tumor; LIHC cis rs965469 1.000 rs1040727 chr20:3264292 G/A cg25506879 chr20:3388711 C20orf194 -0.58 -6.6 -0.34 1.6e-10 IFN-related cytopenia; LIHC trans rs12753920 0.671 rs4658129 chr1:92577848 C/G cg15668468 chr10:118892869 VAX1 0.44 6.3 0.32 8.93e-10 Systemic lupus erythematosus; LIHC cis rs6815814 0.950 rs114719937 chr4:38808585 G/C cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC cis rs12701220 0.655 rs34344742 chr7:1149288 C/G cg26769984 chr7:1090371 C7orf50 0.47 5.83 0.3 1.31e-8 Bronchopulmonary dysplasia; LIHC cis rs892961 1.000 rs2117924 chr17:75401310 C/T cg05865280 chr17:75406074 SEPT9 0.6 12.07 0.55 3.56e-28 Airflow obstruction; LIHC cis rs6952808 0.572 rs1860826 chr7:2112506 G/A cg02951883 chr7:2050386 MAD1L1 -0.59 -9.02 -0.44 1.37e-17 Bipolar disorder and schizophrenia; LIHC trans rs3960554 0.569 rs10464565 chr7:75869526 T/G cg19862616 chr7:65841803 NCRNA00174 0.61 9.28 0.45 2.02e-18 Eotaxin levels; LIHC cis rs12079745 0.793 rs10919156 chr1:169345054 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.81 -7.12 -0.36 6.54e-12 QT interval; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.13 0.55 2e-28 Prudent dietary pattern; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14191109 chr10:70287438 SLC25A16 -0.4 -6.19 -0.32 1.68e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15166552 chr3:156273067 SSR3 0.48 6.24 0.32 1.31e-9 Lung function (FEV1/FVC); LIHC cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg17554472 chr22:41940697 POLR3H -0.54 -5.96 -0.31 6.15e-9 Vitiligo; LIHC cis rs7937682 0.632 rs14133 chr11:111782697 C/G cg09085632 chr11:111637200 PPP2R1B 0.93 13.52 0.59 1.12e-33 Primary sclerosing cholangitis; LIHC cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg00684032 chr4:1343700 KIAA1530 0.36 5.85 0.3 1.15e-8 Obesity-related traits; LIHC cis rs2404602 1.000 rs12443137 chr15:76840832 G/T cg03037974 chr15:76606532 NA 0.72 13.81 0.6 8.39e-35 Blood metabolite levels; LIHC cis rs7769051 1.000 rs9493446 chr6:133125643 C/T cg07930552 chr6:133119739 C6orf192 0.65 6.45 0.33 3.78e-10 Type 2 diabetes nephropathy; LIHC trans rs4714291 0.832 rs3008839 chr6:40052660 G/A cg02267698 chr19:7991119 CTXN1 -0.42 -7.13 -0.36 5.92e-12 Strep throat; LIHC cis rs62380364 0.602 rs640177 chr5:88002084 T/A cg22951263 chr5:87985283 NA -0.39 -6.89 -0.35 2.7e-11 Intelligence (multi-trait analysis); LIHC cis rs7546668 1.000 rs7516435 chr1:15868692 A/G cg11706911 chr1:15910989 AGMAT 0.43 6.49 0.33 3.09e-10 Glomerular filtration rate (creatinine); LIHC cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg17971929 chr21:40555470 PSMG1 0.75 8.56 0.42 3.87e-16 Cognitive function; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg13852536 chr9:32567045 NDUFB6 0.4 6.07 0.31 3.32e-9 Bilirubin levels; LIHC cis rs6964587 0.773 rs17757926 chr7:91987702 T/C cg17063962 chr7:91808500 NA 0.99 17.27 0.68 1.71e-48 Breast cancer; LIHC cis rs12478296 1.000 rs56387669 chr2:243043889 T/C cg06360820 chr2:242988706 NA -0.84 -11.71 -0.54 7.1e-27 Obesity-related traits; LIHC cis rs9296092 0.538 rs75501442 chr6:33519493 A/G cg13560919 chr6:33536144 NA -0.38 -6.44 -0.33 4.1e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs6138458 0.620 rs914314 chr20:24897355 C/T cg26195577 chr20:24973756 C20orf3 -1.05 -9.38 -0.45 9.19e-19 Blood protein levels; LIHC cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg00656387 chr3:40428638 ENTPD3 0.46 7.79 0.39 7.91e-14 Renal cell carcinoma; LIHC cis rs2228479 0.850 rs17232910 chr16:89839766 G/C cg04013166 chr16:89971882 TCF25 0.53 6.67 0.34 1.05e-10 Skin colour saturation; LIHC cis rs67311347 1.000 rs4246666 chr3:40407670 C/T cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.46e-9 Renal cell carcinoma; LIHC cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg12292205 chr6:26970375 C6orf41 -0.47 -8.12 -0.4 8.73e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg16606324 chr3:10149918 C3orf24 0.51 5.81 0.3 1.42e-8 Alzheimer's disease; LIHC cis rs138880 0.505 rs56248708 chr22:50306969 G/A cg09182678 chr22:50328711 NA -0.7 -7.85 -0.39 5.58e-14 Schizophrenia; LIHC cis rs2228479 0.702 rs62053701 chr16:89860584 G/A cg06558623 chr16:89946397 TCF25 0.85 11.09 0.51 1.32e-24 Skin colour saturation; LIHC cis rs10752881 0.967 rs6695837 chr1:182991462 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.41 0.49 3.15e-22 Colorectal cancer; LIHC cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg12016809 chr21:47604291 C21orf56 0.5 7.72 0.39 1.25e-13 Testicular germ cell tumor; LIHC cis rs614226 0.935 rs588132 chr12:121024066 A/G cg01236616 chr12:121019343 POP5 1.23 18.11 0.7 7.3e-52 Type 1 diabetes nephropathy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10235275 chr10:65225544 JMJD1C;LOC84989 -0.45 -6.44 -0.33 4.08e-10 Pancreatic cancer; LIHC cis rs950776 0.518 rs12906846 chr15:78825295 G/A cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg06634786 chr22:41940651 POLR3H -0.75 -8.57 -0.42 3.65e-16 Vitiligo; LIHC cis rs921968 0.643 rs545460 chr2:219392159 A/G cg02985541 chr2:219472218 PLCD4 0.45 8.49 0.42 6.49e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg18252515 chr7:66147081 NA -1.29 -16.56 -0.67 1.23e-45 Diabetic kidney disease; LIHC cis rs9457247 1.000 rs400063 chr6:167386592 C/T cg23791538 chr6:167370224 RNASET2 -0.66 -11.39 -0.52 1.08e-25 Crohn's disease; LIHC cis rs918629 0.679 rs57471342 chr5:95272429 A/C cg10483112 chr5:95245456 ELL2 -0.37 -6.24 -0.32 1.28e-9 IgG glycosylation; LIHC cis rs4253772 0.591 rs6519993 chr22:46656479 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.73 6.63 0.34 1.35e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs9486719 1.000 rs12210146 chr6:96903962 A/G cg06623918 chr6:96969491 KIAA0776 0.69 7.04 0.36 1.05e-11 Migraine;Coronary artery disease; LIHC cis rs986417 1.000 rs1956554 chr14:60963775 C/T cg27398547 chr14:60952738 C14orf39 -0.76 -8.83 -0.43 5.67e-17 Gut microbiota (bacterial taxa); LIHC cis rs9309473 1.000 rs7572722 chr2:73724675 T/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.55 -0.33 2.14e-10 Metabolite levels; LIHC cis rs17685 0.725 rs4476928 chr7:75642107 C/A cg16684958 chr7:75615977 POR -0.51 -8.52 -0.42 5.27e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17152411 0.895 rs7914206 chr10:126585397 G/A cg07906193 chr10:126599966 NA 0.42 6.47 0.33 3.4e-10 Height; LIHC cis rs2302190 0.882 rs7210714 chr17:56675666 A/C cg12560992 chr17:57184187 TRIM37 0.69 8.92 0.43 2.78e-17 Vitamin D levels; LIHC cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg17554472 chr22:41940697 POLR3H 0.56 6.01 0.31 4.84e-9 Vitiligo; LIHC cis rs4764487 0.735 rs2072372 chr12:6344600 C/A cg08284733 chr12:6341482 CD9 0.34 5.82 0.3 1.39e-8 Mean platelet volume; LIHC cis rs10733682 0.633 rs869500 chr9:129465898 G/A cg00232160 chr9:129468157 NA 0.37 6.41 0.33 4.89e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7027203 0.663 rs4428726 chr9:96623559 T/G cg14396892 chr9:96623032 NA -0.32 -6.31 -0.32 8.81e-10 DNA methylation (variation); LIHC cis rs17685 0.784 rs1613890 chr7:75735037 T/C cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.37e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs644799 1.000 rs632388 chr11:95563775 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg26818010 chr10:134567672 INPP5A -0.74 -9.61 -0.46 1.62e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs854765 0.647 rs854770 chr17:18019048 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.39 7.46 0.37 7.05e-13 Total body bone mineral density; LIHC cis rs10028773 0.666 rs12498657 chr4:120262866 G/C cg09307838 chr4:120376055 NA 0.62 9.67 0.46 1.07e-19 Educational attainment; LIHC trans rs11098499 0.954 rs3733523 chr4:120423719 C/T cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs75908454 1.000 rs77395702 chr6:169799664 T/C cg19338460 chr6:170058176 WDR27 -0.58 -5.83 -0.3 1.31e-8 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs11098699 0.821 rs11939262 chr4:124207018 A/G cg09941581 chr4:124220074 SPATA5 0.32 6.38 0.33 5.62e-10 Mosquito bite size; LIHC cis rs10256972 0.521 rs871019 chr7:1105230 A/G cg16145915 chr7:1198662 ZFAND2A -0.25 -5.83 -0.3 1.25e-8 Longevity;Endometriosis; LIHC cis rs769267 0.965 rs2074299 chr19:19380646 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.58 0.46 2.05e-19 Tonsillectomy; LIHC cis rs2839186 0.739 rs7282763 chr21:47696800 C/T cg12379764 chr21:47803548 PCNT -0.61 -8.8 -0.43 7e-17 Testicular germ cell tumor; LIHC cis rs10078 0.559 rs2672725 chr5:434981 G/C cg26072250 chr5:443457 EXOC3;C5orf55 0.68 8.77 0.43 8.6e-17 Fat distribution (HIV); LIHC cis rs6594499 0.843 rs1993465 chr5:110433098 A/G cg04022379 chr5:110408740 TSLP 0.51 8.46 0.42 8.07e-16 Allergic disease (asthma, hay fever or eczema); LIHC cis rs748404 0.660 rs2602141 chr15:43724646 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.23 0.36 3.09e-12 Lung cancer; LIHC cis rs360798 0.512 rs1420018 chr2:63112500 A/G cg17519650 chr2:63277830 OTX1 0.59 8.89 0.43 3.53e-17 Coronary artery disease; LIHC cis rs875971 0.545 rs4718348 chr7:65906576 A/G cg11764359 chr7:65958608 NA 0.58 7.83 0.39 6.1e-14 Aortic root size; LIHC trans rs2727020 0.521 rs7101761 chr11:49598178 G/A cg15704280 chr7:45808275 SEPT13 -0.77 -11.28 -0.52 2.71e-25 Coronary artery disease; LIHC trans rs6489882 0.703 rs1051042 chr12:113357237 G/C cg10175203 chr3:128143634 NA 0.39 6.33 0.32 7.64e-10 Chronic lymphocytic leukemia; LIHC cis rs2239547 0.618 rs2071041 chr3:52864693 T/G cg11645453 chr3:52864694 ITIH4 0.35 9.34 0.45 1.29e-18 Schizophrenia; LIHC cis rs2204008 0.837 rs11611861 chr12:38357459 A/G cg26384229 chr12:38710491 ALG10B 0.6 8.25 0.41 3.42e-15 Bladder cancer; LIHC cis rs6500602 0.702 rs3761680 chr16:4524060 C/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 6.21 0.32 1.54e-9 Schizophrenia; LIHC cis rs8177253 0.965 rs4854761 chr3:133498789 A/G cg12373951 chr3:133503437 NA -0.67 -11.89 -0.54 1.67e-27 Iron status biomarkers; LIHC cis rs8028182 0.501 rs7166281 chr15:75928192 G/T cg20655648 chr15:75932815 IMP3 -0.45 -6.53 -0.33 2.38e-10 Sudden cardiac arrest; LIHC cis rs7523273 0.548 rs2724381 chr1:207949017 T/C cg22525895 chr1:207977042 MIR29B2 0.63 10.22 0.48 1.38e-21 Schizophrenia; LIHC cis rs7772486 0.686 rs857875 chr6:145980033 T/G cg23711669 chr6:146136114 FBXO30 -0.67 -12.11 -0.55 2.54e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs240764 0.817 rs11155596 chr6:101152631 C/T cg09795085 chr6:101329169 ASCC3 -0.51 -7.08 -0.36 8.35e-12 Neuroticism; LIHC cis rs798766 0.903 rs798726 chr4:1685211 C/T cg24127593 chr4:1648399 FAM53A 0.42 5.99 0.31 5.18e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs17270561 0.943 rs76703022 chr6:25703529 A/C cg17691542 chr6:26056736 HIST1H1C 0.64 7.06 0.36 9.57e-12 Iron status biomarkers; LIHC cis rs2297440 0.530 rs34533955 chr20:62233020 A/C cg09650180 chr20:62225654 GMEB2 -0.39 -6.03 -0.31 4.23e-9 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC cis rs72843506 0.586 rs73980762 chr17:19869426 T/C cg12065943 chr17:19881925 AKAP10 -0.38 -6.4 -0.33 5.06e-10 Schizophrenia; LIHC cis rs35110281 0.666 rs2838348 chr21:45107285 C/G cg21573476 chr21:45109991 RRP1B 0.63 12.1 0.55 2.64e-28 Mean corpuscular volume; LIHC cis rs782590 0.967 rs6545506 chr2:55798108 A/G cg03859395 chr2:55845619 SMEK2 -0.83 -14.85 -0.63 7.69e-39 Metabolic syndrome; LIHC cis rs910316 0.737 rs175048 chr14:75479894 A/T cg11812906 chr14:75593930 NEK9 -0.73 -13.56 -0.59 8.13e-34 Height; LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.02 0.35 1.22e-11 Renal cell carcinoma; LIHC cis rs796364 0.664 rs4673660 chr2:200915395 C/T cg23649088 chr2:200775458 C2orf69 0.56 7.57 0.38 3.56e-13 Schizophrenia; LIHC cis rs758324 0.898 rs11958749 chr5:131166014 T/C cg06307176 chr5:131281290 NA 0.41 5.95 0.31 6.75e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7447593 0.626 rs3812036 chr5:176813404 C/T cg06060754 chr5:176797920 RGS14 0.63 9.87 0.47 2.22e-20 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.96 19.32 0.72 9.56e-57 Height; LIHC cis rs17106184 1.000 rs12095997 chr1:51391845 C/T cg07174182 chr1:51127561 FAF1 -0.75 -8.33 -0.41 1.95e-15 Type 2 diabetes; LIHC cis rs35762459 1 rs35762459 chr11:8844653 T/TA cg21881798 chr11:8931708 C11orf17;ST5 -0.38 -6.15 -0.32 2.22e-9 Immature fraction of reticulocytes; LIHC cis rs858239 0.863 rs466225 chr7:23332403 G/T cg00469287 chr7:23338798 C7orf30 0.47 6.1 0.31 2.93e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2019216 0.967 rs2342216 chr17:21910379 A/C cg22648282 chr17:21454238 C17orf51 -0.35 -6.2 -0.32 1.62e-9 Pelvic organ prolapse; LIHC cis rs2197308 0.765 rs11182481 chr12:37926019 T/C cg13010199 chr12:38710504 ALG10B 0.48 5.73 0.3 2.21e-8 Morning vs. evening chronotype; LIHC cis rs4819052 0.851 rs2838842 chr21:46669217 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.56 0.53 2.52e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7772486 0.790 rs9399571 chr6:146282061 A/G cg05347473 chr6:146136440 FBXO30 -0.36 -5.71 -0.3 2.41e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg03264133 chr6:25882463 NA -0.45 -6.75 -0.34 6.16e-11 Height; LIHC cis rs7503807 0.935 rs62068348 chr17:78608575 T/C cg09596252 chr17:78655493 RPTOR 0.38 6.89 0.35 2.62e-11 Obesity; LIHC cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg07636037 chr3:49044803 WDR6 0.77 12.85 0.57 4.23e-31 Menarche (age at onset); LIHC cis rs1801251 1.000 rs2044449 chr2:233718808 G/A cg25237894 chr2:233734115 C2orf82 -0.58 -11.51 -0.53 3.77e-26 Coronary artery disease; LIHC trans rs17685 0.558 rs60787921 chr7:75792844 C/A cg19862616 chr7:65841803 NCRNA00174 0.94 19.23 0.72 2.29e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg15691649 chr6:25882328 NA -0.44 -6.98 -0.35 1.58e-11 Height; LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.14 -0.32 2.28e-9 Total body bone mineral density; LIHC cis rs2832191 0.791 rs2832186 chr21:30484151 A/C cg24692254 chr21:30365293 RNF160 -0.69 -12.58 -0.56 4.33e-30 Dental caries; LIHC cis rs244293 1.000 rs244296 chr17:53242878 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.26 -0.37 2.66e-12 Menarche (age at onset); LIHC cis rs1552244 0.882 rs55962400 chr3:10044457 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 10.13 0.48 2.91e-21 Alzheimer's disease; LIHC cis rs11148252 0.875 rs9596651 chr13:52938582 A/G cg00495681 chr13:53174319 NA -0.39 -6.29 -0.32 9.92e-10 Lewy body disease; LIHC cis rs240764 0.658 rs3811078 chr6:101247503 T/C cg09795085 chr6:101329169 ASCC3 -0.42 -5.83 -0.3 1.31e-8 Neuroticism; LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg10755058 chr3:40428713 ENTPD3 0.4 6.87 0.35 3.05e-11 Renal cell carcinoma; LIHC cis rs3806843 0.900 rs2563287 chr5:140124786 C/T cg19875535 chr5:140030758 IK 0.35 5.96 0.31 6.36e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9457247 0.967 rs376097 chr6:167410878 A/G cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.57 9.0 0.44 1.59e-17 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25654301 chr17:73511699 TSEN54;CASKIN2 0.47 6.27 0.32 1.09e-9 Lung function (FEV1/FVC); LIHC cis rs919433 0.617 rs700643 chr2:198601370 A/G cg03934865 chr2:198174659 NA 0.48 6.85 0.35 3.54e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2842992 0.789 rs4709376 chr6:160226337 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.55 0.56 5.67e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs4700695 0.511 rs29443 chr5:65504927 G/A cg21114390 chr5:65439923 SFRS12 -0.53 -7.74 -0.39 1.14e-13 Facial morphology (factor 19); LIHC cis rs7927592 0.956 rs11228278 chr11:68308530 G/A cg20283391 chr11:68216788 NA -0.53 -8.21 -0.41 4.64e-15 Total body bone mineral density; LIHC cis rs7224737 1.000 rs7219220 chr17:40294280 T/C cg02450064 chr17:40260053 DHX58 -0.3 -6.15 -0.32 2.17e-9 Fibrinogen levels; LIHC cis rs11864453 0.749 rs7192730 chr16:72124219 T/C cg01557791 chr16:72042693 DHODH -0.47 -7.62 -0.38 2.58e-13 Fibrinogen levels; LIHC cis rs8180040 0.726 rs2305634 chr3:47043538 A/G cg02527881 chr3:46936655 PTH1R 0.3 5.87 0.3 1.01e-8 Colorectal cancer; LIHC cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg07061783 chr6:25882402 NA -0.51 -6.54 -0.33 2.21e-10 Intelligence (multi-trait analysis); LIHC cis rs2952156 0.920 rs14050 chr17:37828072 C/T cg00129232 chr17:37814104 STARD3 -0.51 -9.44 -0.45 6.16e-19 Asthma; LIHC cis rs10540 0.558 rs12806062 chr11:501429 G/A cg03352830 chr11:487213 PTDSS2 0.83 6.64 0.34 1.26e-10 Body mass index; LIHC trans rs2727020 0.615 rs4980435 chr11:49591576 G/A cg18944383 chr4:111397179 ENPEP 0.26 6.41 0.33 4.94e-10 Coronary artery disease; LIHC cis rs9733 0.519 rs12095002 chr1:150649249 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Tonsillectomy; LIHC cis rs881375 1.000 rs6478484 chr9:123652380 T/C cg14580859 chr9:123691850 NA 0.37 6.51 0.33 2.67e-10 Rheumatoid arthritis; LIHC cis rs1559088 1.000 rs11672313 chr19:33563190 C/T cg27124370 chr19:33622961 WDR88 0.47 7.04 0.36 1.03e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs17253792 0.915 rs76957332 chr14:56195370 G/A cg26951091 chr14:76844913 ESRRB 0.59 6.48 0.33 3.28e-10 Putamen volume; LIHC cis rs9611565 0.592 rs5996037 chr22:41965292 A/G cg06634786 chr22:41940651 POLR3H -0.61 -6.53 -0.33 2.39e-10 Vitiligo; LIHC cis rs919433 0.927 rs13032495 chr2:198189346 C/T cg10820045 chr2:198174542 NA -0.55 -9.18 -0.44 4.13e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs861020 0.563 rs61820640 chr1:210041297 G/T cg05527609 chr1:210001259 C1orf107 -0.82 -10.42 -0.49 2.81e-22 Orofacial clefts; LIHC cis rs7617773 0.539 rs2017858 chr3:48382282 G/T cg11946769 chr3:48343235 NME6 0.61 7.52 0.38 4.92e-13 Coronary artery disease; LIHC cis rs10876993 0.784 rs7314152 chr12:58017701 T/G cg18357645 chr12:58087776 OS9 -0.5 -7.78 -0.39 8.92e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs924607 0.966 rs1621827 chr5:635074 A/G cg04476341 chr5:669733 TPPP 0.39 8.78 0.43 7.81e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1559088 1.000 rs1559087 chr19:33551041 A/G cg27124370 chr19:33622961 WDR88 0.46 7.09 0.36 7.93e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs12711979 0.509 rs10195596 chr2:3824222 T/G cg17052675 chr2:3827356 NA -0.7 -15.47 -0.64 2.8e-41 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09302904 chr17:62340561 TEX2 0.54 7.13 0.36 5.88e-12 Lung function (FEV1/FVC); LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg06558623 chr16:89946397 TCF25 0.87 13.67 0.59 2.97e-34 Skin colour saturation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20586607 chr14:50235780 KLHDC2 0.45 6.17 0.32 1.89e-9 Pancreatic cancer; LIHC cis rs6963495 0.818 rs73190149 chr7:105152793 C/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs4253772 0.591 rs6007740 chr22:46654323 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.67 -6.05 -0.31 3.87e-9 LDL cholesterol;Cholesterol, total; LIHC cis rs10193935 0.901 rs10202848 chr2:42515661 A/G cg27598129 chr2:42591480 NA -0.68 -10.53 -0.49 1.25e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs924607 0.898 rs905193 chr5:635095 T/C cg24163568 chr5:669837 TPPP 0.39 8.14 0.4 7.4e-15 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6582630 0.537 rs10785436 chr12:38461040 G/C cg13010199 chr12:38710504 ALG10B 0.42 5.75 0.3 1.98e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs7659604 0.643 rs6839375 chr4:122663610 G/C cg19748678 chr4:122722346 EXOSC9 0.42 6.24 0.32 1.3e-9 Type 2 diabetes; LIHC cis rs4273100 0.526 rs2074280 chr17:18917915 A/G cg27028682 chr17:19100026 NA 0.52 7.54 0.38 4.18e-13 Schizophrenia; LIHC cis rs6691722 0.503 rs1142057 chr1:24706292 C/T cg18323236 chr1:24743029 NIPAL3 -0.41 -7.83 -0.39 6.18e-14 Response to interferon beta in multiple sclerosis; LIHC cis rs1552244 0.882 rs17050660 chr3:10001772 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.76 -10.4 -0.49 3.39e-22 Alzheimer's disease; LIHC cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.27 -0.45 2.21e-18 Electroencephalogram traits; LIHC cis rs1005277 0.683 rs7923868 chr10:37989766 T/C cg00409905 chr10:38381863 ZNF37A -0.54 -9.14 -0.44 5.83e-18 Extrinsic epigenetic age acceleration; LIHC cis rs9814567 1.000 rs6763088 chr3:134254989 C/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs208520 0.754 rs851592 chr6:66875175 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.61 -0.42 2.75e-16 Exhaled nitric oxide output; LIHC cis rs924607 1.000 rs11746907 chr5:598224 G/A cg24163568 chr5:669837 TPPP -0.41 -8.43 -0.41 9.44e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs10848704 0.637 rs11062351 chr12:2881763 C/T cg19995117 chr12:2880862 NA 0.36 7.06 0.36 9.47e-12 Quantitative traits; LIHC cis rs769267 0.930 rs4808965 chr19:19631655 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.41 0.37 1.02e-12 Tonsillectomy; LIHC cis rs2839186 0.967 rs4819222 chr21:47707778 G/A cg05896524 chr21:47604654 C21orf56 0.45 6.86 0.35 3.24e-11 Testicular germ cell tumor; LIHC cis rs3008870 0.916 rs2025608 chr1:67422550 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.29 0.66 1.46e-44 Lymphocyte percentage of white cells; LIHC cis rs5769765 0.908 rs56351880 chr22:50316597 A/G cg26441486 chr22:50317300 CRELD2 0.36 6.08 0.31 3.25e-9 Schizophrenia; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6921036 chr6:8455400 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.51 0.42 5.55e-16 Motion sickness; LIHC cis rs3862030 0.694 rs41306870 chr10:104229785 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.27 -0.37 2.42e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs17685 0.753 rs11764129 chr7:75761890 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11098499 0.863 rs2127823 chr4:120485670 G/T cg09307838 chr4:120376055 NA 0.74 11.27 0.52 3e-25 Corneal astigmatism; LIHC cis rs1707322 1.000 rs11211200 chr1:46288352 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.5 0.33 2.92e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3770081 1.000 rs2118521 chr2:86204379 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -8.04 -0.4 1.49e-14 Facial emotion recognition (sad faces); LIHC cis rs240764 0.645 rs239208 chr6:101139285 G/A cg12253828 chr6:101329408 ASCC3 0.43 6.48 0.33 3.14e-10 Neuroticism; LIHC cis rs2050392 0.517 rs2480299 chr10:30743197 G/A cg25182066 chr10:30743637 MAP3K8 -0.72 -11.42 -0.53 8.53e-26 Inflammatory bowel disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04737350 chr12:80170325 PPP1R12A 0.3 6.13 0.31 2.48e-9 Cognitive function; LIHC cis rs4319547 0.656 rs10161534 chr12:122873864 T/C cg05707623 chr12:122985044 ZCCHC8 -0.52 -6.89 -0.35 2.67e-11 Body mass index; LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs2204008 0.837 rs11168504 chr12:37964922 G/T cg13010199 chr12:38710504 ALG10B 0.49 5.75 0.3 1.97e-8 Bladder cancer; LIHC cis rs600806 0.850 rs1343465 chr1:109937426 T/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs9790314 1.000 rs6775627 chr3:160953609 A/G cg04691961 chr3:161091175 C3orf57 -0.42 -6.62 -0.34 1.36e-10 Morning vs. evening chronotype; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg12648201 chr2:27665141 KRTCAP3 -0.42 -5.82 -0.3 1.34e-8 Total body bone mineral density; LIHC cis rs6570726 0.791 rs11155433 chr6:145907831 A/G cg13319975 chr6:146136371 FBXO30 0.35 5.71 0.3 2.43e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs3784262 1.000 rs3784262 chr15:58253106 T/C cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.6 -0.34 1.56e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6500602 0.702 rs11076834 chr16:4549583 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.84 0.39 5.69e-14 Schizophrenia; LIHC cis rs3820500 0.543 rs10923316 chr1:118026778 C/T cg20383390 chr1:117909022 MAN1A2 0.46 6.03 0.31 4.33e-9 Pneumonia; LIHC cis rs11122272 0.735 rs2244994 chr1:231537127 C/G cg06096015 chr1:231504339 EGLN1 0.49 9.18 0.44 4.06e-18 Hemoglobin concentration; LIHC cis rs12478296 1.000 rs11899408 chr2:243014630 A/G cg18898632 chr2:242989856 NA -0.67 -8.78 -0.43 7.83e-17 Obesity-related traits; LIHC trans rs61931739 0.534 rs1384860 chr12:34045388 T/C cg26384229 chr12:38710491 ALG10B 0.45 6.41 0.33 4.71e-10 Morning vs. evening chronotype; LIHC cis rs6951245 1.000 rs2363286 chr7:1091625 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.71 -5.76 -0.3 1.88e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17685 0.672 rs55807301 chr7:75807401 C/A cg01364799 chr7:75623366 TMEM120A -0.5 -7.58 -0.38 3.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12220238 1.000 rs11000894 chr10:75906598 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs75908454 1.000 rs76673185 chr6:169973675 G/C cg19338460 chr6:170058176 WDR27 -0.82 -7.41 -0.37 9.95e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs1401999 0.899 rs2313211 chr3:183738626 T/A cg20387954 chr3:183756860 HTR3D 0.28 6.03 0.31 4.37e-9 Anterior chamber depth; LIHC cis rs3768617 0.706 rs4129858 chr1:183004334 A/G ch.1.3577855R chr1:183094577 LAMC1 0.5 8.02 0.4 1.75e-14 Fuchs's corneal dystrophy; LIHC cis rs12477438 0.715 rs7586608 chr2:99558017 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.46 -0.49 2.18e-22 Chronic sinus infection; LIHC cis rs6088590 0.901 rs6087631 chr20:33403509 T/C cg06115741 chr20:33292138 TP53INP2 0.56 7.64 0.38 2.21e-13 Coronary artery disease; LIHC cis rs6502050 0.842 rs9894129 chr17:80075700 A/G cg11859384 chr17:80120422 CCDC57 0.43 5.9 0.3 8.52e-9 Life satisfaction; LIHC cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs477692 0.905 rs693402 chr10:131422882 G/A cg19680672 chr10:131412579 MGMT -0.42 -6.58 -0.34 1.75e-10 Response to temozolomide; LIHC cis rs523522 0.962 rs9788155 chr12:120938408 G/A cg12219531 chr12:120966889 COQ5 0.67 13.22 0.58 1.57e-32 High light scatter reticulocyte count; LIHC cis rs2072438 0.505 rs7034074 chr9:123923029 A/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.2 0.32 1.63e-9 Rheumatoid arthritis; LIHC cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.645 rs7119101 chr11:49955665 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs13108904 0.539 rs13135102 chr4:1330983 A/C cg13395646 chr4:1353034 KIAA1530 -0.82 -12.49 -0.56 9.48e-30 Obesity-related traits; LIHC cis rs9419702 0.614 rs9419567 chr10:133535149 C/G cg20568497 chr10:133558893 NA 0.41 6.11 0.31 2.7e-9 Survival in rectal cancer; LIHC cis rs875971 0.862 rs7798630 chr7:65771479 G/C cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC trans rs36350 0.624 rs11621415 chr14:72386292 T/C cg16370061 chr5:179226009 MGAT4B;MIR1229 0.35 6.41 0.33 4.72e-10 Autism spectrum disorder or schizophrenia; LIHC cis rs8084351 0.512 rs2068861 chr18:50806973 G/A cg24270629 chr18:50823537 DCC -0.51 -7.64 -0.38 2.26e-13 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs250677 0.687 rs250663 chr5:148453117 T/C cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC trans rs6866721 0.765 rs62374490 chr5:116214852 G/A cg07571379 chr11:134631427 NA -0.29 -6.09 -0.31 3.08e-9 Body mass index; LIHC cis rs6545883 0.929 rs778155 chr2:61647901 A/G cg15711740 chr2:61764176 XPO1 0.43 6.06 0.31 3.57e-9 Tuberculosis; LIHC cis rs59698941 0.943 rs10491277 chr5:132236361 G/C cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs67311347 0.910 rs7617361 chr3:40373259 G/T cg13409248 chr3:40428643 ENTPD3 0.4 6.58 0.34 1.74e-10 Renal cell carcinoma; LIHC cis rs853679 0.517 rs2275508 chr6:28094731 T/C cg16479474 chr6:28041457 NA 0.46 6.58 0.34 1.79e-10 Depression; LIHC cis rs9640161 0.742 rs2108851 chr7:150019634 T/C cg17279839 chr7:150038598 RARRES2 0.5 10.58 0.5 8.39e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs921968 0.541 rs562510 chr2:219443001 A/C cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.63e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2295359 1.000 rs11465753 chr1:67631423 T/C cg12940439 chr1:67600707 NA 0.39 7.05 0.36 1e-11 Psoriasis; LIHC cis rs12701220 0.689 rs12536282 chr7:1115650 C/T cg02733842 chr7:1102375 C7orf50 -0.68 -7.61 -0.38 2.63e-13 Bronchopulmonary dysplasia; LIHC cis rs3749237 0.595 rs10865955 chr3:49499829 G/A cg02487422 chr3:49467188 NICN1 0.42 6.51 0.33 2.63e-10 Resting heart rate; LIHC cis rs909002 0.849 rs3753611 chr1:32082486 C/T cg13919466 chr1:32135498 COL16A1 -0.3 -5.99 -0.31 5.3300000000000004e-09 Intelligence (multi-trait analysis); LIHC cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg04317338 chr11:64019027 PLCB3 0.86 10.8 0.5 1.41e-23 Mean platelet volume; LIHC cis rs8180040 0.764 rs13084117 chr3:47183239 C/A cg16586182 chr3:47516702 SCAP -0.5 -8.93 -0.43 2.66e-17 Colorectal cancer; LIHC cis rs858239 0.601 rs929507 chr7:23166664 G/C cg23682824 chr7:23144976 KLHL7 0.45 6.68 0.34 9.63e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2834188 0.889 rs2040108 chr21:34676158 T/C cg14352951 chr21:34696688 IFNAR1 0.44 6.11 0.31 2.75e-9 Narcolepsy; LIHC cis rs9486719 0.947 rs11757102 chr6:96885073 G/A cg06623918 chr6:96969491 KIAA0776 -0.72 -7.15 -0.36 5.19e-12 Migraine;Coronary artery disease; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg11070056 chr1:107600091 PRMT6 -0.72 -12.42 -0.56 1.67e-29 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7412746 0.611 rs2271076 chr1:150916657 C/T cg18016565 chr1:150552671 MCL1 0.5 9.51 0.46 3.62e-19 Melanoma; LIHC trans rs62458065 0.513 rs10268149 chr7:32575499 T/C cg00845942 chr12:64062724 DPY19L2 -0.55 -6.05 -0.31 3.77e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs11711311 0.911 rs9831422 chr3:113398195 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.39 6.65 0.34 1.2e-10 IgG glycosylation; LIHC cis rs4653767 1.000 rs708773 chr1:226920730 T/C cg05262829 chr1:226921576 ITPKB 0.43 8.24 0.41 3.8e-15 Parkinson's disease; LIHC trans rs4927850 1.000 rs7627706 chr3:195753353 A/C cg21051086 chr3:73046214 PPP4R2 -0.38 -6.08 -0.31 3.19e-9 Pancreatic cancer; LIHC trans rs3783890 1.000 rs71419270 chr14:93772500 T/A cg02802420 chr16:69363236 PDF;COG8 0.32 6.25 0.32 1.24e-9 Body mass index; LIHC cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.27 -0.55 6.42e-29 Alzheimer's disease; LIHC cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 2.97e-30 Menopause (age at onset); LIHC cis rs13108904 0.875 rs1564509 chr4:1236562 C/G cg16405210 chr4:1374714 KIAA1530 -0.45 -6.78 -0.34 5.16e-11 Obesity-related traits; LIHC cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg07424592 chr7:64974309 NA 0.8 9.43 0.45 6.25e-19 Diabetic kidney disease; LIHC cis rs2274273 0.870 rs10142547 chr14:55763963 T/C cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.37e-9 Protein biomarker; LIHC cis rs7520050 0.931 rs1707333 chr1:46547035 C/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.85 0.3 1.16e-8 Red blood cell count;Reticulocyte count; LIHC cis rs35306767 0.855 rs2050944 chr10:918910 T/C cg26597838 chr10:835615 NA 1.18 14.34 0.61 7.88e-37 Eosinophil percentage of granulocytes; LIHC trans rs3112255 1.000 rs2137674 chr2:101305228 C/A cg06958034 chr1:23346203 KDM1A -0.46 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs2279817 0.780 rs1124447 chr1:18007598 A/G cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.73 -0.39 1.2e-13 Neuroticism; LIHC cis rs904251 0.523 rs2776920 chr6:37480605 G/A cg01843034 chr6:37503916 NA -0.47 -8.06 -0.4 1.31e-14 Cognitive performance; LIHC cis rs4975709 0.589 rs4975744 chr5:1860049 A/G cg14773178 chr5:1868261 NA 0.26 6.91 0.35 2.45e-11 Cardiovascular disease risk factors; LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs28735056 0.967 rs56071379 chr18:77647406 G/A cg20368463 chr18:77673604 PQLC1 -0.36 -6.1 -0.31 2.86e-9 Schizophrenia; LIHC cis rs7044106 0.791 rs12554440 chr9:123485333 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.62 9.52 0.46 3.16e-19 Hip circumference adjusted for BMI; LIHC cis rs1005277 0.579 rs1780115 chr10:38524773 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs807029 0.533 rs3740486 chr10:102750623 T/C cg27255678 chr10:102756921 LZTS2 0.51 7.31 0.37 1.89e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs11212737 0.739 rs2624145 chr11:108520478 A/G cg22776369 chr11:108536276 DDX10 0.38 6.21 0.32 1.55e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg10862848 chr6:42927986 GNMT -0.26 -6.29 -0.32 9.47e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs903552 1.000 rs8041563 chr15:102005824 G/C cg19295451 chr15:102010161 PCSK6 -0.46 -6.33 -0.32 7.51e-10 Diabetic kidney disease; LIHC cis rs3099143 0.901 rs78020233 chr15:77107050 T/G cg21673338 chr15:77095150 SCAPER -0.53 -7.34 -0.37 1.53e-12 Recalcitrant atopic dermatitis; LIHC cis rs3749237 0.595 rs3870337 chr3:49557095 G/T cg02487422 chr3:49467188 NICN1 0.37 5.71 0.3 2.45e-8 Resting heart rate; LIHC cis rs8078723 0.510 rs3859189 chr17:38137033 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.71 12.99 0.57 1.21e-31 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7772486 0.875 rs9403768 chr6:146406458 A/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.0 -0.31 4.92e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg23758822 chr17:41437982 NA 0.94 17.99 0.7 2.25e-51 Menopause (age at onset); LIHC cis rs6088590 1.000 rs6087626 chr20:33347328 C/T cg24642439 chr20:33292090 TP53INP2 0.79 11.34 0.52 1.64e-25 Coronary artery disease; LIHC cis rs2075371 0.796 rs7780583 chr7:133960716 C/G cg20476274 chr7:133979776 SLC35B4 0.69 9.31 0.45 1.63e-18 Mean platelet volume; LIHC cis rs12477438 0.798 rs13393860 chr2:99590397 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.87 -0.47 2.27e-20 Chronic sinus infection; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20347042 chr7:2122685 MAD1L1 0.38 6.05 0.31 3.7e-9 Longevity; LIHC cis rs4240897 0.935 rs3766744 chr1:12043717 G/A cg13216073 chr1:12042593 MFN2 0.47 7.64 0.38 2.2e-13 Tuberculosis; LIHC cis rs2760061 0.545 rs1745423 chr1:228224153 G/T cg01200585 chr1:228362443 C1orf69 -0.45 -6.64 -0.34 1.23e-10 Diastolic blood pressure; LIHC cis rs2075371 0.897 rs1646702 chr7:134000177 C/G cg11752832 chr7:134001865 SLC35B4 0.52 7.65 0.38 2.01e-13 Mean platelet volume; LIHC cis rs7223966 1.000 rs9901112 chr17:61730617 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.73 0.34 7.34e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs11583043 0.874 rs6577219 chr1:101415707 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 8.49 0.42 6.56e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg00106254 chr7:1943704 MAD1L1 0.43 6.97 0.35 1.61e-11 Bipolar disorder and schizophrenia; LIHC cis rs9393692 0.846 rs7771202 chr6:26279907 A/G cg13736514 chr6:26305472 NA -0.38 -6.39 -0.33 5.41e-10 Educational attainment; LIHC cis rs62103177 0.564 rs11874805 chr18:77697110 T/C cg20368463 chr18:77673604 PQLC1 0.54 6.85 0.35 3.47e-11 Opioid sensitivity; LIHC cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg13397359 chr6:42928475 GNMT 0.79 11.3 0.52 2.19e-25 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs12477438 0.520 rs6741772 chr2:99738961 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.45 0.64 3.26e-41 Chronic sinus infection; LIHC cis rs10876993 0.928 rs2928053 chr12:58063475 T/C cg15848620 chr12:58087721 OS9 -0.56 -7.67 -0.38 1.85e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs4819052 0.885 rs28576202 chr21:46674684 G/A cg11663144 chr21:46675770 NA -0.32 -5.92 -0.31 7.69e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs244293 1.000 rs244293 chr17:53230722 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.36 -0.33 6.38e-10 Menarche (age at onset); LIHC cis rs9309473 1.000 rs11903916 chr2:73815328 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.87 -0.35 2.97e-11 Metabolite levels; LIHC cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg09455208 chr3:40491958 NA 0.34 6.78 0.34 5.26e-11 Renal cell carcinoma; LIHC cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg16606324 chr3:10149918 C3orf24 0.52 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs6088590 0.648 rs6059991 chr20:33280836 C/T cg24642439 chr20:33292090 TP53INP2 0.48 6.68 0.34 9.97e-11 Coronary artery disease; LIHC cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.77 0.69 1.69e-50 Gut microbiome composition (summer); LIHC trans rs5756813 0.754 rs11089854 chr22:38148882 G/A cg19894588 chr14:64061835 NA -0.61 -8.3 -0.41 2.49e-15 Optic cup area;Vertical cup-disc ratio; LIHC cis rs4638749 0.677 rs13414687 chr2:108806245 A/G cg25838818 chr2:108905173 SULT1C2 -0.38 -6.82 -0.35 4.26e-11 Blood pressure; LIHC cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg03579045 chr8:11579013 GATA4 0.39 5.75 0.3 2.03e-8 Monocyte count; LIHC cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg18230493 chr5:56204884 C5orf35 -0.44 -6.16 -0.32 2.08e-9 Initial pursuit acceleration; LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg00106254 chr7:1943704 MAD1L1 -0.48 -8.01 -0.4 1.84e-14 Bipolar disorder and schizophrenia; LIHC cis rs763121 0.819 rs3747173 chr22:39069045 A/G cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs208520 0.526 rs4710310 chr6:66802808 T/C cg07460842 chr6:66804631 NA -1.03 -20.26 -0.74 1.58e-60 Exhaled nitric oxide output; LIHC cis rs79149102 0.579 rs12591175 chr15:75356073 C/T cg15902774 chr15:75289873 SCAMP5 0.44 6.49 0.33 3.08e-10 Lung cancer; LIHC cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg08219700 chr8:58056026 NA 0.5 6.34 0.32 7.14e-10 Developmental language disorder (linguistic errors); LIHC cis rs1198430 0.759 rs1198438 chr1:23749557 C/G cg13183780 chr1:23809682 ASAP3 -0.38 -6.68 -0.34 9.44e-11 Total cholesterol levels; LIHC cis rs2976388 0.609 rs1560986 chr8:143789775 T/C cg13446199 chr8:143762866 PSCA -0.2 -5.78 -0.3 1.71e-8 Urinary tract infection frequency; LIHC cis rs12200782 1.000 rs12205909 chr6:26630999 G/A cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs2404602 0.669 rs1875885 chr15:76638081 G/A cg03037974 chr15:76606532 NA 0.84 17.63 0.69 6.28e-50 Blood metabolite levels; LIHC cis rs1559088 0.948 rs7259333 chr19:33579128 T/C cg27124370 chr19:33622961 WDR88 0.55 8.78 0.43 8.02e-17 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1401999 0.565 rs4912515 chr3:183653718 A/G cg01324343 chr3:183735012 ABCC5 0.37 6.08 0.31 3.25e-9 Anterior chamber depth; LIHC cis rs10089 0.953 rs10045113 chr5:127386631 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.84 0.35 3.67e-11 Ileal carcinoids; LIHC cis rs10504229 0.871 rs60342323 chr8:58154899 T/C cg02290350 chr8:58132656 NA 0.37 7.99 0.4 2.13e-14 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.754 rs12199362 chr6:146118225 A/G cg13319975 chr6:146136371 FBXO30 -0.4 -6.53 -0.33 2.37e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg11060661 chr22:24314208 DDT;DDTL 0.63 10.46 0.49 2.05e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs35110281 0.633 rs762400 chr21:45113629 C/G cg21573476 chr21:45109991 RRP1B 0.58 11.17 0.52 6.74e-25 Mean corpuscular volume; LIHC cis rs8084351 0.577 rs10502959 chr18:50678732 C/T cg24270629 chr18:50823537 DCC -0.44 -6.67 -0.34 1.05e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9522267 0.535 rs9522305 chr13:112237550 A/G cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs8053891 0.502 rs34679758 chr16:71995427 A/G cg04254540 chr16:71951199 KIAA0174 -0.76 -6.96 -0.35 1.69e-11 Coronary artery disease; LIHC cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.36 -0.37 1.4e-12 Electroencephalogram traits; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg10150615 chr22:24372951 LOC391322 -0.57 -8.24 -0.41 3.66e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7528419 0.895 rs1277930 chr1:109822143 G/A cg20569855 chr1:109824440 PSRC1 0.49 6.32 0.32 7.99e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs10248839 0.518 rs1317741 chr7:29711149 T/C cg19413766 chr7:29689036 LOC646762 -0.62 -6.35 -0.32 6.78e-10 Facial emotion recognition (angry faces); LIHC cis rs13020137 1 rs13020137 chr2:130757304 A/G cg09663323 chr2:130956255 TUBA3E 0.46 7.05 0.36 1.01e-11 Schizophrenia; LIHC cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.59 0.56 3.89e-30 Colonoscopy-negative controls vs population controls; LIHC cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg09323728 chr8:95962352 TP53INP1 -0.27 -5.86 -0.3 1.06e-8 Type 2 diabetes; LIHC cis rs2991971 0.934 rs7903 chr1:45976472 G/C cg24296786 chr1:45957014 TESK2 0.54 8.04 0.4 1.5e-14 High light scatter reticulocyte count; LIHC cis rs7904368 0.754 rs12246217 chr10:16853349 G/C cg14835575 chr10:16859367 RSU1 0.65 8.95 0.44 2.27e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs6424115 0.708 rs12748109 chr1:24181177 C/T cg15997130 chr1:24165203 NA -0.36 -6.54 -0.33 2.31e-10 Immature fraction of reticulocytes; LIHC cis rs74233809 1.000 rs34747231 chr10:104942244 T/G cg03493300 chr10:104813866 CNNM2 0.45 5.93 0.31 7.42e-9 Birth weight; LIHC cis rs3820068 0.581 rs56128111 chr1:15928948 T/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs11673344 0.750 rs111543213 chr19:37642385 C/A cg27390819 chr19:37464633 NA -0.51 -6.23 -0.32 1.35e-9 Obesity-related traits; LIHC cis rs9790314 0.934 rs465985 chr3:161098552 T/C cg04691961 chr3:161091175 C3orf57 -0.42 -6.49 -0.33 3.04e-10 Morning vs. evening chronotype; LIHC cis rs875971 0.545 rs67775320 chr7:65658779 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.48 0.37 6.36e-13 Aortic root size; LIHC cis rs11603020 0.950 rs28362948 chr11:57369013 A/C cg19752551 chr11:57585705 CTNND1 -0.54 -6.73 -0.34 7.15e-11 Blood protein levels; LIHC cis rs7618501 0.521 rs34654589 chr3:49911449 C/G cg21467203 chr3:49911342 NA -0.6 -10.9 -0.51 6.2e-24 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.724 rs9347340 chr6:160188891 C/T cg19482086 chr6:160211437 TCP1;MRPL18 -0.71 -13.15 -0.58 3.1e-32 Age-related macular degeneration (geographic atrophy); LIHC cis rs9814567 0.793 rs55940445 chr3:134306064 G/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.43 6.17 0.32 1.89e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg11766577 chr21:47581405 C21orf56 -0.38 -6.01 -0.31 4.86e-9 Testicular germ cell tumor; LIHC cis rs6500602 0.787 rs7204624 chr16:4459834 A/G cg08645402 chr16:4508243 NA 0.34 5.78 0.3 1.65e-8 Schizophrenia; LIHC cis rs847649 0.767 rs11972261 chr7:102641244 T/G cg18108683 chr7:102477205 FBXL13 0.44 6.6 0.34 1.57e-10 Morning vs. evening chronotype; LIHC cis rs4409675 0.576 rs11247706 chr1:28213983 G/C cg23691781 chr1:28212827 C1orf38 0.32 7.63 0.38 2.32e-13 Corneal astigmatism; LIHC cis rs2834256 0.886 rs7281625 chr21:35066836 A/C cg14850771 chr21:34775459 IFNGR2 -0.42 -6.54 -0.33 2.24e-10 Red cell distribution width; LIHC cis rs769267 0.965 rs12977937 chr19:19429975 C/G cg03709012 chr19:19516395 GATAD2A 0.91 15.46 0.64 3.01e-41 Tonsillectomy; LIHC cis rs6952808 0.501 rs3778999 chr7:2180885 G/A cg22963979 chr7:1858916 MAD1L1 -0.35 -5.73 -0.3 2.2e-8 Bipolar disorder and schizophrenia; LIHC cis rs5769765 0.865 rs10854860 chr22:50320029 G/T cg26441486 chr22:50317300 CRELD2 0.39 6.59 0.34 1.65e-10 Schizophrenia; LIHC cis rs116095464 0.558 rs62346506 chr5:201594 T/C cg22496380 chr5:211416 CCDC127 -1.19 -10.59 -0.5 7.59e-23 Breast cancer; LIHC trans rs7618501 0.966 rs7372966 chr3:49788969 T/C cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.6 -0.34 1.58e-10 Intelligence (multi-trait analysis); LIHC cis rs11585357 0.895 rs877552 chr1:17631236 C/T cg08277548 chr1:17600880 PADI3 -0.56 -6.08 -0.31 3.13e-9 Hair shape; LIHC cis rs2354432 0.607 rs6593751 chr1:146726023 A/G cg25205988 chr1:146714368 CHD1L -0.9 -10.93 -0.51 4.65e-24 Mitochondrial DNA levels; LIHC cis rs3741404 0.791 rs11603192 chr11:63927695 A/G cg18225595 chr11:63971243 STIP1 0.68 10.93 0.51 4.64e-24 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14877741 chr9:125703099 RABGAP1 0.44 6.34 0.32 7.45e-10 Pancreatic cancer; LIHC cis rs4906332 0.966 rs7401563 chr14:103964425 G/A cg04998671 chr14:104000505 TRMT61A -0.46 -6.2 -0.32 1.67e-9 Coronary artery disease; LIHC cis rs244293 0.965 rs244303 chr17:53238728 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.2 -0.32 1.6e-9 Menarche (age at onset); LIHC cis rs2073499 0.810 rs78501918 chr3:50369914 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.68 7.0 0.35 1.36e-11 Schizophrenia; LIHC trans rs7618501 0.933 rs6809431 chr3:49804119 A/G cg21659725 chr3:3221576 CRBN 0.99 19.71 0.73 2.65e-58 Intelligence (multi-trait analysis); LIHC cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg16405210 chr4:1374714 KIAA1530 -0.72 -10.96 -0.51 3.71e-24 Longevity; LIHC cis rs4988958 0.527 rs3771155 chr2:103037826 A/G cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma (childhood onset); LIHC cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg14983838 chr19:29218262 NA 0.48 7.51 0.38 5.23e-13 Methadone dose in opioid dependence; LIHC cis rs6546550 0.901 rs6754896 chr2:70138170 T/C cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC cis rs919433 0.713 rs13411968 chr2:198467141 C/T cg10820045 chr2:198174542 NA 0.51 8.09 0.4 1.03e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3806843 0.966 rs2563260 chr5:140137867 C/A cg26395211 chr5:140044315 WDR55 0.42 6.24 0.32 1.32e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg16049864 chr8:95962084 TP53INP1 -0.63 -11.88 -0.54 1.78e-27 Type 2 diabetes; LIHC cis rs2073300 0.793 rs6048814 chr20:23448411 A/C cg12062639 chr20:23401060 NAPB 0.81 9.62 0.46 1.56e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4819052 0.851 rs2838864 chr21:46711474 A/T cg22633049 chr21:46681294 NA 0.37 6.39 0.33 5.42e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9916302 0.706 rs4794808 chr17:37531916 C/T cg07936489 chr17:37558343 FBXL20 0.86 12.17 0.55 1.45e-28 Glomerular filtration rate (creatinine); LIHC cis rs694739 0.726 rs17857342 chr11:64138905 T/G cg23796481 chr11:64053134 BAD;GPR137 0.47 6.24 0.32 1.32e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs67478160 0.643 rs8005594 chr14:104279889 T/C cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.5 -0.38 5.56e-13 Schizophrenia; LIHC cis rs9640161 0.789 rs4554381 chr7:150025567 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.51 -9.04 -0.44 1.22e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs4332037 0.539 rs4719416 chr7:2106608 G/A cg23422044 chr7:1970798 MAD1L1 -0.59 -8.91 -0.43 3.17e-17 Bipolar disorder; LIHC cis rs17854409 0.881 rs68091818 chr20:61479882 A/C cg06598544 chr20:61472147 COL9A3 -0.79 -7.82 -0.39 6.46e-14 Obesity-related traits; LIHC cis rs11031096 0.711 rs10835723 chr11:4207566 G/C cg18678763 chr11:4115507 RRM1 -0.41 -6.0 -0.31 4.93e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2236918 1.000 rs735943 chr1:242030151 C/T cg17736920 chr1:242011382 EXO1 -0.59 -8.86 -0.43 4.53e-17 Menopause (age at onset); LIHC cis rs2932538 0.883 rs6696991 chr1:113095661 C/T cg22162597 chr1:113214053 CAPZA1 0.66 10.35 0.49 5.05e-22 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs17739167 0.550 rs17739125 chr15:42234424 T/C cg20935245 chr15:42234343 EHD4 -0.42 -7.82 -0.39 6.41e-14 Monocyte count; LIHC cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg15857475 chr8:145742913 RECQL4;LRRC14 -0.55 -8.17 -0.4 6.15e-15 Age at first birth; LIHC cis rs2072499 0.868 rs2758600 chr1:156195205 C/T cg25208724 chr1:156163844 SLC25A44 0.84 13.24 0.58 1.39e-32 Testicular germ cell tumor; LIHC cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg04546413 chr19:29218101 NA 0.56 10.27 0.49 9.71e-22 Methadone dose in opioid dependence; LIHC cis rs240764 0.817 rs6905221 chr6:101151537 G/A cg09795085 chr6:101329169 ASCC3 -0.52 -7.25 -0.36 2.82e-12 Neuroticism; LIHC cis rs919433 0.927 rs7592748 chr2:198170688 G/A cg10820045 chr2:198174542 NA -0.57 -9.48 -0.46 4.3e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs716804 0.703 rs7947666 chr11:10305095 A/T cg01453529 chr11:10209919 SBF2 -0.29 -5.84 -0.3 1.19e-8 Neuroticism; LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg16145915 chr7:1198662 ZFAND2A -0.43 -11.51 -0.53 3.9e-26 Longevity;Endometriosis; LIHC cis rs9916302 0.904 rs9904334 chr17:37468336 G/A cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10797726 chr6:82957093 IBTK 0.41 6.18 0.32 1.83e-9 Cognitive function; LIHC cis rs921968 0.541 rs549026 chr2:219339283 T/C cg02985541 chr2:219472218 PLCD4 0.43 7.03 0.36 1.15e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9611565 0.592 rs9611612 chr22:41961189 T/C cg06634786 chr22:41940651 POLR3H -0.58 -6.45 -0.33 3.82e-10 Vitiligo; LIHC cis rs861020 0.563 rs35898529 chr1:210053096 G/A cg05527609 chr1:210001259 C1orf107 -0.81 -10.36 -0.49 4.52e-22 Orofacial clefts; LIHC cis rs9818758 0.607 rs10049462 chr3:49309684 C/T cg06212747 chr3:49208901 KLHDC8B -0.68 -5.95 -0.31 6.67e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg13173722 chr20:60553138 TAF4 0.41 6.18 0.32 1.82e-9 Bilirubin levels; LIHC cis rs12908161 1.000 rs35524990 chr15:85258203 T/C cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC trans rs561341 1.000 rs757009 chr17:30243937 A/G cg20587970 chr11:113659929 NA -0.64 -7.54 -0.38 4.27e-13 Hip circumference adjusted for BMI; LIHC cis rs7592578 0.825 rs12477369 chr2:191455624 G/T cg27211696 chr2:191398769 TMEM194B 0.6 7.61 0.38 2.73e-13 Diastolic blood pressure; LIHC cis rs4076764 0.958 rs11590567 chr1:163396438 A/G cg24596788 chr1:163392923 NA -0.25 -7.75 -0.39 1.08e-13 Motion sickness; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg25084332 chr12:62997409 MIRLET7I;C12orf61 -0.39 -6.35 -0.32 6.8e-10 Eotaxin levels; LIHC trans rs7246657 0.882 rs10422667 chr19:37937876 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs9303401 0.659 rs17222523 chr17:56620501 A/G cg25039879 chr17:56429692 SUPT4H1 0.75 8.44 0.42 8.81e-16 Cognitive test performance; LIHC cis rs7412746 0.634 rs7521592 chr1:150821691 A/C cg17724175 chr1:150552817 MCL1 0.47 9.02 0.44 1.38e-17 Melanoma; LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg21782813 chr7:2030301 MAD1L1 -0.42 -6.89 -0.35 2.7e-11 Bipolar disorder and schizophrenia; LIHC cis rs6456156 0.792 rs10946213 chr6:167516095 A/G cg07741184 chr6:167504864 NA -0.27 -6.52 -0.33 2.46e-10 Primary biliary cholangitis; LIHC trans rs10411161 0.702 rs10403189 chr19:52400673 A/G cg22319618 chr22:45562946 NUP50 0.64 8.62 0.42 2.61e-16 Breast cancer; LIHC cis rs4665809 0.590 rs11126339 chr2:26253223 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.66 -8.39 -0.41 1.31e-15 Gut microbiome composition (summer); LIHC trans rs4596713 0.508 rs4076287 chr9:71755333 A/G cg16512924 chr15:28394682 HERC2 0.39 6.12 0.31 2.56e-9 Headache; LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg20570016 chr1:156261298 TMEM79 0.38 6.11 0.31 2.75e-9 Tonsillectomy; LIHC cis rs3733346 0.553 rs6813110 chr4:942660 C/T cg08222618 chr4:941054 TMEM175 0.69 13.22 0.58 1.6e-32 Sjögren's syndrome; LIHC cis rs4689592 0.503 rs11937667 chr4:7057037 C/G cg19539972 chr4:7069911 GRPEL1 -0.69 -9.72 -0.47 6.92e-20 Monocyte percentage of white cells; LIHC cis rs12477438 0.798 rs4324365 chr2:99623845 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.72 -0.5 2.62e-23 Chronic sinus infection; LIHC cis rs2455799 0.573 rs2470539 chr3:15717844 C/T cg12698662 chr3:15914712 MIR563 -0.39 -7.16 -0.36 4.94e-12 Mean platelet volume; LIHC cis rs2607426 1.000 rs2230694 chr19:41263403 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.48 -5.99 -0.31 5.41e-9 Blood protein levels; LIHC cis rs4638749 0.677 rs13389470 chr2:108806301 C/G cg06795125 chr2:108905320 SULT1C2 -0.29 -5.81 -0.3 1.42e-8 Blood pressure; LIHC cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg08067268 chr2:26466485 HADHB;HADHA 0.43 6.55 0.33 2.13e-10 Gut microbiome composition (summer); LIHC cis rs614226 0.935 rs7956998 chr12:120994932 G/A cg27489772 chr12:121021490 NA 0.52 5.72 0.3 2.33e-8 Type 1 diabetes nephropathy; LIHC cis rs11190604 1.000 rs2489051 chr10:102351785 C/T cg07080220 chr10:102295463 HIF1AN -0.52 -7.24 -0.36 3.08e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs611744 0.647 rs9969614 chr8:109260581 A/G cg18478394 chr8:109455254 TTC35 0.43 7.59 0.38 3.15e-13 Dupuytren's disease; LIHC cis rs8062405 0.965 rs56040780 chr16:28861881 C/T cg16576597 chr16:28551801 NUPR1 0.38 6.2 0.32 1.6e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3796352 1.000 rs61172708 chr3:52996052 T/G cg07884673 chr3:53033167 SFMBT1 0.9 6.59 0.34 1.65e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs882732 1.000 rs10147337 chr14:95025560 A/T cg14866387 chr14:95027382 SERPINA4 -0.45 -6.03 -0.31 4.16e-9 Blood protein levels; LIHC cis rs11719291 0.833 rs11713694 chr3:48833615 G/T cg07636037 chr3:49044803 WDR6 -0.81 -8.08 -0.4 1.15e-14 Cognitive function; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg00106254 chr7:1943704 MAD1L1 -0.44 -7.06 -0.36 9.31e-12 Bipolar disorder and schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15910486 chr5:142783621 NR3C1 0.46 6.15 0.32 2.17e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.866 rs9995136 chr4:120286845 A/G cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs9467773 0.967 rs6456732 chr6:26514445 T/C cg09904177 chr6:26538194 HMGN4 0.66 13.89 0.6 4.28e-35 Intelligence (multi-trait analysis); LIHC cis rs240764 0.631 rs6932158 chr6:101246010 T/C cg09795085 chr6:101329169 ASCC3 -0.42 -6.15 -0.32 2.17e-9 Neuroticism; LIHC cis rs11676348 0.755 rs1008562 chr2:219026972 G/C cg20019365 chr2:219134978 PNKD;AAMP 0.52 7.02 0.36 1.17e-11 Ulcerative colitis; LIHC trans rs4927850 0.881 rs7630489 chr3:195753401 T/C cg21051086 chr3:73046214 PPP4R2 -0.38 -6.08 -0.31 3.19e-9 Pancreatic cancer; LIHC cis rs477692 1.000 rs554792 chr10:131423181 A/G cg19680672 chr10:131412579 MGMT -0.45 -6.86 -0.35 3.33e-11 Response to temozolomide; LIHC cis rs735860 0.763 rs6458912 chr6:53147965 G/A cg10236188 chr6:53219634 NA -0.41 -7.4 -0.37 1.05e-12 Glaucoma; LIHC trans rs3960554 0.808 rs60481386 chr7:75700962 A/G cg19862616 chr7:65841803 NCRNA00174 0.62 8.8 0.43 6.96e-17 Eotaxin levels; LIHC cis rs875971 0.862 rs6460306 chr7:66060793 T/C cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.26e-34 Aortic root size; LIHC trans rs7674212 0.570 rs6841136 chr4:104103509 A/C cg16471864 chr4:38666270 KLF3;FLJ13197 -0.43 -6.07 -0.31 3.33e-9 Type 2 diabetes; LIHC cis rs1577917 1.000 rs13194429 chr6:86646705 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.82 -0.5 1.19e-23 Response to antipsychotic treatment; LIHC cis rs4713118 0.512 rs2622319 chr6:28120401 G/C cg25329415 chr6:28076851 NA 0.27 5.81 0.3 1.46e-8 Parkinson's disease; LIHC cis rs7264396 0.563 rs2425109 chr20:34316218 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.66 -0.42 1.94e-16 Total cholesterol levels; LIHC cis rs11792861 0.855 rs72607165 chr9:111814498 C/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.6 -0.34 1.55e-10 Menarche (age at onset); LIHC cis rs986417 1.000 rs11158293 chr14:61109020 G/C cg27398547 chr14:60952738 C14orf39 0.65 6.47 0.33 3.43e-10 Gut microbiota (bacterial taxa); LIHC cis rs1559088 0.948 rs12610071 chr19:33582687 A/C cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg08888203 chr3:10149979 C3orf24 0.61 6.58 0.34 1.78e-10 Alzheimer's disease; LIHC cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg23982607 chr1:1823379 GNB1 -0.68 -13.2 -0.58 1.95e-32 Body mass index; LIHC cis rs9733 0.680 rs3738484 chr1:150552330 G/T cg17724175 chr1:150552817 MCL1 -0.37 -7.45 -0.37 7.83e-13 Tonsillectomy; LIHC cis rs7100689 0.725 rs10736340 chr10:82061071 C/T cg00277334 chr10:82204260 NA -0.55 -6.91 -0.35 2.43e-11 Post bronchodilator FEV1; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07757386 chr14:102771445 RAGE 0.4 6.06 0.31 3.59e-9 Pancreatic cancer; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg27432699 chr2:27873401 GPN1 -0.51 -7.31 -0.37 1.94e-12 Total body bone mineral density; LIHC cis rs12908161 1.000 rs58416181 chr15:85264461 G/A cg03959625 chr15:84868606 LOC388152 0.42 5.79 0.3 1.63e-8 Schizophrenia; LIHC cis rs1395 0.744 rs9653564 chr2:27472618 G/A cg22903471 chr2:27725779 GCKR -0.41 -6.16 -0.32 2e-9 Blood metabolite levels; LIHC cis rs763121 0.853 rs2205802 chr22:39046327 T/C cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs8017423 0.967 rs2277514 chr14:90723059 T/C cg14092571 chr14:90743983 NA -0.38 -6.03 -0.31 4.33e-9 Mortality in heart failure; LIHC cis rs61041384 0.661 rs4474478 chr12:123734368 C/T cg00376283 chr12:123451042 ABCB9 -0.61 -6.45 -0.33 3.89e-10 Schizophrenia; LIHC cis rs10791097 0.694 rs7106684 chr11:130758153 A/T cg22079354 chr11:130786696 SNX19 0.43 6.11 0.31 2.76e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9902453 0.753 rs7226121 chr17:28208125 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.13 0.58 3.53e-32 Coffee consumption (cups per day); LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg11494091 chr17:61959527 GH2 0.44 8.19 0.4 5.4e-15 Prudent dietary pattern; LIHC cis rs7715806 0.517 rs34340 chr5:74932099 A/C cg19683494 chr5:74908142 NA 0.47 6.28 0.32 1.01e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs911555 0.706 rs10129426 chr14:104018455 C/T cg24130564 chr14:104152367 KLC1 -0.44 -7.74 -0.39 1.16e-13 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.958 rs16876530 chr6:86595641 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.97 -0.4 2.46e-14 Response to antipsychotic treatment; LIHC cis rs1055129 0.537 rs10852766 chr17:73951864 T/C cg08125733 chr17:73851984 WBP2 -0.53 -7.97 -0.4 2.34e-14 White matter hyperintensity burden; LIHC cis rs7539409 0.915 rs6576945 chr1:84252882 A/G cg10977910 chr1:84465055 TTLL7 0.77 6.14 0.32 2.26e-9 Alzheimer's disease; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg21724239 chr8:58056113 NA 0.57 7.62 0.38 2.58e-13 Developmental language disorder (linguistic errors); LIHC cis rs787274 1.000 rs787280 chr9:115539085 C/T cg13803584 chr9:115635662 SNX30 -0.56 -6.35 -0.32 6.91e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9733 0.566 rs72702554 chr1:150678234 A/G cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.1e-9 Tonsillectomy; LIHC cis rs2991971 0.934 rs2991974 chr1:46020654 A/G cg24296786 chr1:45957014 TESK2 0.5 7.22 0.36 3.35e-12 High light scatter reticulocyte count; LIHC cis rs6500602 0.702 rs4786511 chr16:4571645 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.15 0.32 2.13e-9 Schizophrenia; LIHC cis rs9910055 0.550 rs113844752 chr17:42297631 C/A cg19774624 chr17:42201019 HDAC5 -0.42 -5.93 -0.31 7.55e-9 Total body bone mineral density; LIHC cis rs12048904 0.512 rs932798 chr1:101249355 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.54 -8.99 -0.44 1.69e-17 Multiple sclerosis; LIHC trans rs61931739 0.500 rs34167298 chr12:34534338 G/A cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs8049603 0.947 rs12922614 chr16:23090069 T/A cg16484020 chr16:23217411 SCNN1G -0.25 -5.71 -0.3 2.44e-8 Multiple sclerosis; LIHC cis rs11958404 0.517 rs35212858 chr5:157238942 T/C cg05962755 chr5:157440814 NA 0.67 6.76 0.34 5.96e-11 IgG glycosylation; LIHC cis rs875971 0.929 rs12673810 chr7:65923853 T/A cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.15 -0.44 5.31e-18 Bipolar disorder; LIHC cis rs8180040 0.701 rs7617689 chr3:46996442 C/T cg02527881 chr3:46936655 PTH1R 0.36 7.3 0.37 2.02e-12 Colorectal cancer; LIHC cis rs782590 0.967 rs62165173 chr2:55741666 T/C cg18811423 chr2:55921094 PNPT1 0.97 14.97 0.63 2.61e-39 Metabolic syndrome; LIHC cis rs11644362 1.000 rs12918494 chr16:12988455 C/T cg06890432 chr16:12997467 SHISA9 -0.4 -6.86 -0.35 3.34e-11 Positive affect;Subjective well-being; LIHC cis rs1707322 1.000 rs7532204 chr1:46485075 C/G cg06784218 chr1:46089804 CCDC17 -0.36 -6.47 -0.33 3.33e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7107174 1.000 rs11237438 chr11:77998488 T/C cg02023728 chr11:77925099 USP35 0.51 9.67 0.46 1e-19 Testicular germ cell tumor; LIHC cis rs2070488 0.775 rs4679066 chr3:38568527 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.69 -11.25 -0.52 3.47e-25 Electrocardiographic conduction measures; LIHC cis rs701145 0.556 rs355763 chr3:154012881 C/T cg16511985 chr3:153974050 SGEF 0.42 8.92 0.43 2.79e-17 Coronary artery disease; LIHC trans rs2797160 0.967 rs2226158 chr6:125995467 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.49 -7.43 -0.37 8.74e-13 Endometrial cancer; LIHC cis rs3741404 0.672 rs4980524 chr11:63959259 A/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 12.26 0.55 6.6e-29 Platelet count; LIHC cis rs6754311 0.638 rs1011361 chr2:136553639 G/A cg07169764 chr2:136633963 MCM6 -0.7 -9.95 -0.47 1.19e-20 Mosquito bite size; LIHC cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg24101359 chr6:42928495 GNMT 0.43 5.81 0.3 1.4e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1451375 1.000 rs921451 chr7:50623285 A/G cg14593290 chr7:50529359 DDC 0.38 6.41 0.33 4.71e-10 Malaria; LIHC trans rs8002861 0.870 rs2875541 chr13:44417441 G/T cg17145862 chr1:211918768 LPGAT1 0.57 10.52 0.49 1.36e-22 Leprosy; LIHC cis rs1144333 1.000 rs17097841 chr1:76462641 T/A cg10523679 chr1:76189770 ACADM 0.42 5.96 0.31 6.4e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7223966 1.000 rs72848797 chr17:61934664 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.74 0.34 6.75e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs79149102 0.579 rs3816261 chr15:75336173 T/A cg09165964 chr15:75287851 SCAMP5 -0.63 -7.87 -0.39 4.84e-14 Lung cancer; LIHC cis rs8114671 0.562 rs8117491 chr20:33510120 T/C cg07148914 chr20:33460835 GGT7 0.67 10.25 0.48 1.14e-21 Height; LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg05856399 chr6:109804852 ZBTB24 0.43 6.19 0.32 1.73e-9 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs10461617 0.541 rs832575 chr5:56161787 C/T cg22800045 chr5:56110881 MAP3K1 0.56 5.8 0.3 1.47e-8 Type 2 diabetes; LIHC cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.42 0.33 4.49e-10 Schizophrenia; LIHC cis rs6545883 0.894 rs778157 chr2:61554289 C/G cg15711740 chr2:61764176 XPO1 -0.43 -5.83 -0.3 1.29e-8 Tuberculosis; LIHC cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg08280861 chr8:58055591 NA 0.51 6.04 0.31 4.06e-9 Developmental language disorder (linguistic errors); LIHC cis rs1728785 1.000 rs1099296 chr16:68588653 G/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.32 2.29e-9 Ulcerative colitis; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs950169 1.000 rs1911155 chr15:84787635 A/G cg17507749 chr15:85114479 UBE2QP1 0.74 7.52 0.38 4.86e-13 Schizophrenia; LIHC cis rs1200821 0.529 rs2475206 chr10:37802532 A/G cg25427524 chr10:38739819 LOC399744 0.45 7.51 0.38 5.07e-13 Hemostatic factors and hematological phenotypes; LIHC cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg06238570 chr21:40685208 BRWD1 0.62 7.51 0.38 5.29e-13 Cognitive function; LIHC cis rs10911232 0.507 rs4652769 chr1:183009196 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.01e-22 Hypertriglyceridemia; LIHC cis rs17826219 0.706 rs61643715 chr17:29057762 A/G cg14067834 chr17:29058358 SUZ12P 0.69 6.91 0.35 2.39e-11 Body mass index; LIHC trans rs17685 0.784 rs1613890 chr7:75735037 T/C cg19862616 chr7:65841803 NCRNA00174 0.92 18.56 0.71 1.05e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2230307 0.536 rs6677998 chr1:100461046 G/A cg24955406 chr1:100503596 HIAT1 0.61 6.15 0.32 2.22e-9 Carotid intima media thickness; LIHC cis rs5769765 0.818 rs8140681 chr22:50292081 C/A cg26441486 chr22:50317300 CRELD2 0.36 6.38 0.33 5.73e-10 Schizophrenia; LIHC cis rs4888262 0.508 rs4544266 chr16:74660993 C/A cg01733217 chr16:74700730 RFWD3 0.8 15.65 0.65 5.15e-42 Testicular germ cell tumor; LIHC cis rs10791323 0.593 rs10791329 chr11:133716356 T/C cg06766960 chr11:133703094 NA -0.68 -11.39 -0.52 1.04e-25 Childhood ear infection; LIHC cis rs17854409 0.536 rs3765464 chr20:61485236 T/C cg06598544 chr20:61472147 COL9A3 -0.79 -7.77 -0.39 8.98e-14 Obesity-related traits; LIHC cis rs11958404 0.932 rs76601259 chr5:157430337 C/T cg05962755 chr5:157440814 NA 1.04 11.66 0.53 1.09e-26 IgG glycosylation; LIHC trans rs11098499 0.954 rs12502423 chr4:120424172 A/C cg25214090 chr10:38739885 LOC399744 0.57 9.34 0.45 1.31e-18 Corneal astigmatism; LIHC cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.49 6.94 0.35 2.03e-11 Height; LIHC cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg18252515 chr7:66147081 NA -1.24 -15.97 -0.65 2.67e-43 Diabetic kidney disease; LIHC cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg02951883 chr7:2050386 MAD1L1 -0.55 -8.28 -0.41 2.87e-15 Bipolar disorder and schizophrenia; LIHC cis rs941408 0.515 rs1640262 chr19:2779134 C/T cg06609049 chr19:2785107 THOP1 -0.77 -13.1 -0.58 4.58e-32 Total cholesterol levels; LIHC cis rs933688 1.000 rs985434 chr5:90744509 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.39 0.66 5.8e-45 Smoking behavior; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg22212156 chr20:32031449 SNTA1 -0.61 -6.17 -0.32 1.88e-9 Mean platelet volume; LIHC cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs757110 0.900 rs2074314 chr11:17411821 C/T cg15432903 chr11:17409602 KCNJ11 0.69 10.62 0.5 5.84e-23 Type 2 diabetes; LIHC cis rs7267979 1.000 rs6050559 chr20:25329915 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.47 6.96 0.35 1.72e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs1882538 0.569 rs11562036 chr7:133076862 T/C cg10665199 chr7:133106180 EXOC4 0.53 8.47 0.42 7.52e-16 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs4646961 chr1:76217169 G/A cg22875332 chr1:76189707 ACADM 0.49 7.29 0.37 2.2e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9611565 0.592 rs80477 chr22:42001183 C/T cg06634786 chr22:41940651 POLR3H 0.58 6.16 0.32 2e-9 Vitiligo; LIHC cis rs1707322 0.963 rs10789478 chr1:46350506 C/T cg06784218 chr1:46089804 CCDC17 0.37 6.5 0.33 2.92e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11284414 chr2:232573146 PTMA -0.44 -6.52 -0.33 2.47e-10 Cognitive function; LIHC cis rs8180040 0.764 rs11718795 chr3:47218727 G/A cg02527881 chr3:46936655 PTH1R -0.32 -6.26 -0.32 1.16e-9 Colorectal cancer; LIHC cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg18404041 chr3:52824283 ITIH1 -0.55 -8.97 -0.44 2.04e-17 Bipolar disorder; LIHC cis rs11628318 0.570 rs4906231 chr14:103062227 T/C cg12046867 chr14:103022105 NA -0.48 -7.03 -0.36 1.14e-11 Platelet count; LIHC cis rs2731664 0.792 rs2630763 chr5:176901005 T/A cg23176889 chr5:176863531 GRK6 -0.68 -11.89 -0.54 1.56e-27 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.836 rs4911183 chr20:34181553 G/A cg04508476 chr20:34239394 CPNE1;RBM12 0.55 8.94 0.44 2.51e-17 Total cholesterol levels; LIHC cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg18252515 chr7:66147081 NA 1.29 16.89 0.67 5.55e-47 Diabetic kidney disease; LIHC cis rs965469 0.779 rs2236121 chr20:3304320 A/G cg25506879 chr20:3388711 C20orf194 -0.46 -5.78 -0.3 1.73e-8 IFN-related cytopenia; LIHC cis rs12220238 1.000 rs10824110 chr10:75968098 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.2 0.32 1.6e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7772486 0.875 rs854145 chr6:146349650 C/T cg23711669 chr6:146136114 FBXO30 0.6 10.48 0.49 1.77e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.838 rs11845950 chr14:90723962 T/A cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.15e-41 Mortality in heart failure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21353724 chr7:2303981 SNX8 -0.41 -6.43 -0.33 4.3e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs929354 0.742 rs62491945 chr7:156955580 G/A cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs908922 0.676 rs11205031 chr1:152527662 C/T cg20991723 chr1:152506922 NA 0.57 10.02 0.48 7.07e-21 Hair morphology; LIHC cis rs7843479 1.000 rs2054711 chr8:21818060 A/G cg17168535 chr8:21777572 XPO7 0.42 6.59 0.34 1.63e-10 Mean corpuscular volume; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08292968 chr12:111020671 PPTC7 -0.42 -6.1 -0.31 2.91e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1395 0.778 rs2078616 chr2:27441904 A/G cg23587288 chr2:27483067 SLC30A3 -0.32 -6.03 -0.31 4.19e-9 Blood metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19864851 chr10:75503847 SEC24C 0.47 7.3 0.37 2.01e-12 Cognitive function; LIHC cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg25894440 chr7:65020034 NA -0.57 -6.27 -0.32 1.11e-9 Diabetic kidney disease; LIHC cis rs9916302 0.904 rs9898773 chr17:37532507 C/G cg03013999 chr17:37608204 MED1 -0.36 -5.91 -0.3 8.4e-9 Glomerular filtration rate (creatinine); LIHC cis rs6500602 0.893 rs4786489 chr16:4485527 G/A cg08645402 chr16:4508243 NA 0.37 6.86 0.35 3.26e-11 Schizophrenia; LIHC cis rs6442522 0.678 rs12634346 chr3:15500295 C/T cg16303742 chr3:15540471 COLQ 0.44 7.37 0.37 1.33e-12 Uric acid levels; LIHC cis rs4660306 1.000 rs2077808 chr1:45988115 G/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.67 -0.34 1.02e-10 Homocysteine levels; LIHC cis rs9457247 0.756 rs1811123 chr6:167403443 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.02 -0.51 2.28e-24 Crohn's disease; LIHC cis rs9640161 0.617 rs56019796 chr7:150009226 T/C cg21361702 chr7:150065534 REPIN1 0.5 6.8 0.35 4.59e-11 Blood protein levels;Circulating chemerin levels; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs7131987 0.903 rs2194520 chr12:29423712 C/T cg21522988 chr12:29376872 FAR2 0.28 6.08 0.31 3.16e-9 QT interval; LIHC cis rs12472274 0.646 rs11677736 chr2:239087198 A/T cg17459225 chr2:239074497 NA 0.71 11.41 0.53 9e-26 Phospholipid levels (plasma); LIHC trans rs12478296 0.901 rs67951957 chr2:243004901 A/G cg01596870 chr19:55963115 NA -0.67 -9.61 -0.46 1.58e-19 Obesity-related traits; LIHC cis rs4684776 0.867 rs13062308 chr3:11355139 C/T cg00170343 chr3:11313890 ATG7 -0.53 -7.32 -0.37 1.8e-12 Small vessel stroke; LIHC cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg13395646 chr4:1353034 KIAA1530 -0.42 -6.05 -0.31 3.9e-9 Longevity; LIHC cis rs769267 0.825 rs1469713 chr19:19528806 A/G cg03709012 chr19:19516395 GATAD2A 1.02 18.18 0.7 3.74e-52 Tonsillectomy; LIHC cis rs6546550 0.935 rs10202159 chr2:70062454 G/T cg02498382 chr2:70120550 SNRNP27 -0.39 -6.54 -0.33 2.24e-10 Prevalent atrial fibrillation; LIHC cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg04025307 chr7:1156635 C7orf50 -0.6 -10.29 -0.49 8.32e-22 Longevity;Endometriosis; LIHC cis rs10193935 1.000 rs10180528 chr2:42436723 T/A cg27598129 chr2:42591480 NA -0.75 -11.48 -0.53 4.84e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs6424115 1.000 rs4649115 chr1:24155731 A/G cg15997130 chr1:24165203 NA -0.45 -9.24 -0.45 2.71e-18 Immature fraction of reticulocytes; LIHC cis rs3815700 1.000 rs8104726 chr19:33094675 G/A cg02997394 chr19:33096574 ANKRD27 0.73 9.38 0.45 9.34e-19 Eosinophilic esophagitis; LIHC cis rs12478296 1.000 rs73007129 chr2:243000555 T/C cg05760424 chr2:242988095 NA -0.53 -6.97 -0.35 1.61e-11 Obesity-related traits; LIHC trans rs2352908 1.000 rs2352913 chr14:49453094 T/C cg01449224 chr4:123073775 NA -0.47 -6.25 -0.32 1.25e-9 Social communication problems; LIHC cis rs79149102 0.579 rs79916508 chr15:75373721 A/C cg09165964 chr15:75287851 SCAMP5 -0.55 -7.22 -0.36 3.48e-12 Lung cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19941170 chr5:172067912 NEURL1B 0.5 7.29 0.37 2.14e-12 Lung function (FEV1/FVC); LIHC cis rs8141529 0.600 rs16986825 chr22:29300306 C/T cg15103426 chr22:29168792 CCDC117 0.45 6.24 0.32 1.27e-9 Lymphocyte counts; LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs13392177 0.684 rs11695527 chr2:219068103 A/G cg00012203 chr2:219082015 ARPC2 0.73 10.86 0.51 8.42e-24 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs3741798 1.000 rs61922023 chr12:12485555 G/A cg08615371 chr12:12503544 MANSC1 0.99 7.88 0.39 4.4e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs3008870 1.000 rs1137656 chr1:67451602 A/C cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC trans rs13113518 0.812 rs2035692 chr4:56394968 T/A cg15358633 chr12:38710606 ALG10B 0.43 6.16 0.32 2.09e-9 Height; LIHC cis rs875971 1.000 rs6961717 chr7:65587537 C/T cg11764359 chr7:65958608 NA -0.87 -15.09 -0.63 8.7e-40 Aortic root size; LIHC cis rs7903847 0.620 rs17112674 chr10:99122178 C/T cg20016023 chr10:99160130 RRP12 0.4 6.5 0.33 2.78e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10139443 chr6:99963249 USP45 -0.4 -6.32 -0.32 8.08e-10 Pancreatic cancer; LIHC cis rs7903847 0.642 rs9888026 chr10:99159869 G/T cg08345082 chr10:99160200 RRP12 0.39 6.71 0.34 8.19e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs10876993 0.855 rs1689585 chr12:58080140 A/G cg15848620 chr12:58087721 OS9 0.56 7.64 0.38 2.18e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs11958404 0.615 rs7727924 chr5:157433736 A/G cg05962755 chr5:157440814 NA 0.63 8.24 0.41 3.77e-15 IgG glycosylation; LIHC cis rs7412746 0.658 rs10305714 chr1:150800655 C/T cg17724175 chr1:150552817 MCL1 -0.44 -9.08 -0.44 9.14e-18 Melanoma; LIHC cis rs1559088 0.847 rs10416218 chr19:33599127 T/C cg17764715 chr19:33622953 WDR88 0.43 6.14 0.31 2.33e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs8180040 0.966 rs13059519 chr3:47539969 C/T cg16586182 chr3:47516702 SCAP -0.57 -11.07 -0.51 1.55e-24 Colorectal cancer; LIHC cis rs2637266 1.000 rs7081214 chr10:78361134 G/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.97e-9 Pulmonary function; LIHC cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg21448741 chr8:58168803 NA 0.39 6.08 0.31 3.26e-9 Developmental language disorder (linguistic errors); LIHC cis rs2279817 0.735 rs12067869 chr1:17989765 G/T cg21791023 chr1:18019539 ARHGEF10L -0.43 -5.89 -0.3 9.14e-9 Neuroticism; LIHC cis rs240764 0.658 rs705584 chr6:101261553 C/T cg09795085 chr6:101329169 ASCC3 0.53 7.3 0.37 1.99e-12 Neuroticism; LIHC cis rs12497850 0.897 rs6795025 chr3:49081247 T/C cg07636037 chr3:49044803 WDR6 0.95 17.13 0.68 6.02e-48 Parkinson's disease; LIHC cis rs1144333 1.000 rs112401426 chr1:76466103 T/A cg10523679 chr1:76189770 ACADM 0.42 5.97 0.31 6.09e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs473651 0.692 rs579511 chr2:239334914 C/G cg18131467 chr2:239335373 ASB1 1.08 20.69 0.75 2.94e-62 Multiple system atrophy; LIHC cis rs9399135 0.904 rs4895438 chr6:135317665 G/T cg22676075 chr6:135203613 NA 0.38 6.22 0.32 1.44e-9 Red blood cell count; LIHC cis rs8180040 0.654 rs11714373 chr3:47214817 G/A cg16586182 chr3:47516702 SCAP 0.48 8.48 0.42 6.98e-16 Colorectal cancer; LIHC cis rs79149102 0.737 rs7163332 chr15:75193623 C/T cg16226627 chr15:75307476 SCAMP5 0.44 6.28 0.32 1.04e-9 Lung cancer; LIHC cis rs10504229 0.679 rs2218271 chr8:58052446 T/A cg20607798 chr8:58055168 NA 0.45 6.05 0.31 3.76e-9 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg27297192 chr10:134578999 INPP5A -0.51 -6.96 -0.35 1.74e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3106136 0.967 rs2632399 chr4:95153741 G/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.99 -0.4 2.03e-14 Capecitabine sensitivity; LIHC cis rs2404602 0.679 rs12900494 chr15:76912504 A/G cg03037974 chr15:76606532 NA 0.74 14.33 0.61 8.31e-37 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21830413 chr10:70884251 VPS26A -0.42 -6.31 -0.32 8.51e-10 Pancreatic cancer; LIHC cis rs2976388 0.609 rs1469811 chr8:143787999 C/T cg06565975 chr8:143823917 SLURP1 0.33 6.47 0.33 3.34e-10 Urinary tract infection frequency; LIHC cis rs34779708 0.966 rs12775799 chr10:35488264 C/T cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.5e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2067615 0.507 rs11113083 chr12:107073316 C/A cg15890332 chr12:107067104 RFX4 0.27 6.43 0.33 4.34e-10 Heart rate; LIHC cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg23262073 chr20:60523788 NA -0.28 -5.76 -0.3 1.88e-8 Body mass index; LIHC cis rs9942416 0.660 rs34905687 chr5:74997736 A/G cg19683494 chr5:74908142 NA 0.57 7.62 0.38 2.49e-13 Age-related disease endophenotypes; LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg08677398 chr8:58056175 NA 0.41 6.32 0.32 8.32e-10 Developmental language disorder (linguistic errors); LIHC cis rs9918079 0.542 rs12499412 chr4:15602252 G/C cg24225360 chr4:15471699 CC2D2A 0.38 6.07 0.31 3.46e-9 Obesity-related traits; LIHC cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.99 8.73 0.43 1.15e-16 Platelet count; LIHC trans rs9929218 0.551 rs6499193 chr16:68727069 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.88 20.32 0.74 9.1e-61 Colorectal cancer; LIHC cis rs6912958 0.781 rs3757368 chr6:88224495 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.09 -0.4 1.05e-14 Monocyte percentage of white cells; LIHC cis rs7249142 0.549 rs72997174 chr19:19294389 T/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.84 -0.35 3.58e-11 IgG glycosylation; LIHC cis rs3741798 1.000 rs78807762 chr12:12484136 G/A cg08615371 chr12:12503544 MANSC1 0.99 7.86 0.39 5.02e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg06453172 chr10:134556979 INPP5A -0.63 -7.99 -0.4 2.05e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2228479 0.681 rs10153055 chr16:89965842 C/T cg00800038 chr16:89945340 TCF25 -0.58 -8.62 -0.42 2.52e-16 Skin colour saturation; LIHC cis rs55823223 0.702 rs3785437 chr17:73906222 G/T cg10935138 chr17:73851978 WBP2 0.77 6.61 0.34 1.51e-10 Psoriasis; LIHC cis rs9649213 0.593 rs35983874 chr7:97916461 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.87 -0.3 1.02e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs10883723 0.810 rs2296582 chr10:104244139 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.16 0.55 1.6e-28 Allergic disease (asthma, hay fever or eczema); LIHC trans rs916888 0.821 rs199504 chr17:44861003 C/T cg16836995 chr17:43662488 NA 0.71 7.25 0.36 2.72e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2839186 0.587 rs35679325 chr21:47640980 A/G cg09417038 chr21:47716443 C21orf57 0.54 8.17 0.4 5.84e-15 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg24209194 chr3:40518798 ZNF619 -0.6 -9.3 -0.45 1.68e-18 Renal cell carcinoma; LIHC cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg19302996 chr17:73780495 UNK -0.5 -6.16 -0.32 2.05e-9 Psoriasis; LIHC cis rs796364 1.000 rs35220450 chr2:200780737 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -5.78 -0.3 1.71e-8 Schizophrenia; LIHC cis rs9583531 0.600 rs1441043 chr13:111367650 A/G cg24331049 chr13:111365604 ING1 0.8 13.65 0.59 3.75e-34 Coronary artery disease; LIHC cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg05590025 chr7:65112418 INTS4L2 0.61 6.68 0.34 9.69e-11 Diabetic kidney disease; LIHC cis rs34779708 0.766 rs7897088 chr10:35551567 G/T cg03585969 chr10:35415529 CREM 0.76 10.71 0.5 2.89e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7605378 0.567 rs717915 chr2:200714766 C/T cg17644776 chr2:200775616 C2orf69 0.44 6.27 0.32 1.1e-9 Osteoporosis; LIHC cis rs763121 0.853 rs5757187 chr22:39021522 A/G cg14440974 chr22:39074834 NA 0.44 7.18 0.36 4.25e-12 Menopause (age at onset); LIHC cis rs79149102 0.579 rs59303424 chr15:75370014 G/A cg15902774 chr15:75289873 SCAMP5 0.4 5.95 0.31 6.63e-9 Lung cancer; LIHC cis rs4788570 0.615 rs9888756 chr16:71740477 G/A cg06353428 chr16:71660113 MARVELD3 1.37 14.83 0.63 8.96e-39 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.579 rs1780133 chr10:38499509 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.92 -13.87 -0.6 5.19e-35 Alzheimer's disease; LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26329020 chr12:32909488 YARS2 0.44 6.06 0.31 3.63e-9 Pancreatic cancer; LIHC cis rs6665290 0.870 rs17600725 chr1:227204231 A/G cg10327440 chr1:227177885 CDC42BPA -1.13 -22.5 -0.77 1.92e-69 Myeloid white cell count; LIHC cis rs8062405 0.723 rs35175818 chr16:28608746 A/C cg07451762 chr16:28383216 NA 0.41 7.12 0.36 6.24e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1577917 1.000 rs9647603 chr6:86639341 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.81 -0.39 7.29e-14 Response to antipsychotic treatment; LIHC cis rs1707322 0.963 rs6429581 chr1:46319096 G/A cg03146154 chr1:46216737 IPP 0.48 7.52 0.38 4.99e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC trans rs7246657 0.943 rs4803229 chr19:37864682 T/G cg10208301 chr11:6592745 DNHD1 0.46 6.6 0.34 1.61e-10 Coronary artery calcification; LIHC cis rs7208859 0.623 rs56163556 chr17:29101868 G/C cg13385521 chr17:29058706 SUZ12P 0.83 8.18 0.4 5.73e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg05185784 chr16:90016020 DEF8 -0.48 -6.21 -0.32 1.53e-9 Skin colour saturation; LIHC cis rs3770081 1.000 rs3810827 chr2:86334386 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.88 -9.26 -0.45 2.39e-18 Facial emotion recognition (sad faces); LIHC cis rs11018874 0.735 rs4307680 chr11:89900630 A/C cg05041596 chr11:89867385 NAALAD2 0.43 6.81 0.35 4.43e-11 White blood cell types; LIHC cis rs79839061 0.610 rs34006051 chr4:847445 C/T cg07828340 chr4:882639 GAK 0.83 6.68 0.34 9.65e-11 Intelligence (multi-trait analysis); LIHC cis rs922107 0.675 rs6428548 chr1:89941533 G/A cg15422784 chr1:90023713 LRRC8B 0.45 7.03 0.36 1.14e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs2072499 0.695 rs112223391 chr1:156156094 G/A cg24450063 chr1:156163899 SLC25A44 0.77 8.31 0.41 2.31e-15 Testicular germ cell tumor; LIHC cis rs9942416 0.617 rs72633979 chr5:74990178 A/T cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs1400745 0.756 rs799683 chr14:35349236 G/A cg16230307 chr14:35515116 FAM177A1 0.39 6.21 0.32 1.53e-9 Monocyte count; LIHC cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg05368731 chr17:41323189 NBR1 0.73 12.58 0.56 4.43e-30 Menopause (age at onset); LIHC cis rs5769765 0.646 rs9627789 chr22:50300562 A/G cg02269571 chr22:50332266 NA -0.66 -8.96 -0.44 2.16e-17 Schizophrenia; LIHC cis rs67311347 0.713 rs73073505 chr3:40310693 C/T cg18306943 chr3:40428807 ENTPD3 0.38 6.28 0.32 1.03e-9 Renal cell carcinoma; LIHC cis rs7412746 0.588 rs10305664 chr1:150839686 A/C cg15448220 chr1:150897856 SETDB1 0.39 5.78 0.3 1.7e-8 Melanoma; LIHC cis rs1580019 0.563 rs13244332 chr7:32537679 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.13 0.44 6.17e-18 Cognitive ability; LIHC cis rs11786130 1.000 rs62512837 chr8:129008290 T/G cg01765152 chr8:129005526 PVT1 -0.3 -6.38 -0.33 5.68e-10 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs2439831 0.681 rs2444036 chr15:43694108 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.93 0.51 4.89e-24 Lung cancer in ever smokers; LIHC cis rs2228479 0.702 rs11076620 chr16:89831520 A/T cg00800038 chr16:89945340 TCF25 -0.61 -8.97 -0.44 1.96e-17 Skin colour saturation; LIHC cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg12463550 chr7:65579703 CRCP -0.66 -6.85 -0.35 3.41e-11 Diabetic kidney disease; LIHC cis rs11122272 0.735 rs2246645 chr1:231497393 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -10.96 -0.51 3.7e-24 Hemoglobin concentration; LIHC cis rs12594515 1.000 rs7173144 chr15:45991196 A/G cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC cis rs6722750 0.651 rs12987393 chr2:64421514 C/T cg22352474 chr2:64371530 PELI1 0.41 5.82 0.3 1.37e-8 Neuroticism; LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg02782426 chr3:40428986 ENTPD3 0.34 6.42 0.33 4.5e-10 Renal cell carcinoma; LIHC trans rs1994135 0.608 rs1482994 chr12:33713631 T/C cg26384229 chr12:38710491 ALG10B 0.48 6.63 0.34 1.29e-10 Resting heart rate; LIHC cis rs74233809 1.000 rs12221335 chr10:104769392 T/A cg03493300 chr10:104813866 CNNM2 0.45 6.06 0.31 3.69e-9 Birth weight; LIHC cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg23758822 chr17:41437982 NA 0.91 16.84 0.67 8.86e-47 Menopause (age at onset); LIHC cis rs11098499 0.954 rs10518331 chr4:120323595 C/T cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs238295 0.805 rs6053523 chr20:5571964 A/G cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -6.89 -0.35 2.69e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs1577917 0.839 rs6454492 chr6:86483214 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.39 -6.92 -0.35 2.23e-11 Response to antipsychotic treatment; LIHC cis rs7937890 0.684 rs12799007 chr11:14426484 T/A cg23387056 chr11:14280742 SPON1 -0.44 -5.98 -0.31 5.49e-9 Mitochondrial DNA levels; LIHC cis rs7267979 1.000 rs2257432 chr20:25271086 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg13409248 chr3:40428643 ENTPD3 -0.43 -7.26 -0.37 2.63e-12 Renal cell carcinoma; LIHC cis rs1865760 0.892 rs6456705 chr6:25936056 G/A cg03517284 chr6:25882590 NA -0.44 -6.64 -0.34 1.21e-10 Height; LIHC cis rs2997447 0.846 rs61775428 chr1:26409126 G/C cg19633962 chr1:26362018 EXTL1 -0.7 -6.32 -0.32 8.04e-10 QRS complex (12-leadsum); LIHC cis rs611744 0.647 rs585077 chr8:109245497 C/T cg18478394 chr8:109455254 TTC35 0.39 6.74 0.34 6.88e-11 Dupuytren's disease; LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg14671364 chr1:107599128 PRMT6 -0.54 -7.93 -0.39 3.08e-14 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs783540 0.967 rs2567635 chr15:83262181 T/G cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.66 -0.34 1.09e-10 Schizophrenia; LIHC cis rs7903847 0.642 rs11189178 chr10:99143272 T/G cg06359132 chr10:99160096 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18509826 chr3:52017385 ACY1 0.46 6.71 0.34 7.89e-11 Calcium levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11815682 chr21:44486381 CBS 0.41 6.06 0.31 3.53e-9 Bilirubin levels; LIHC cis rs12286929 0.610 rs12807135 chr11:115053508 G/C cg04055981 chr11:115044050 NA 0.5 7.95 0.39 2.75e-14 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg13409248 chr3:40428643 ENTPD3 0.49 8.31 0.41 2.24e-15 Renal cell carcinoma; LIHC cis rs7584330 0.737 rs1497129 chr2:238369184 C/T cg14458575 chr2:238380390 NA 0.38 5.98 0.31 5.54e-9 Prostate cancer; LIHC cis rs7552404 1.000 rs211723 chr1:76103030 C/T cg03433033 chr1:76189801 ACADM -0.66 -9.42 -0.45 6.79e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11123170 0.650 rs2289897 chr2:113977454 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.47 5.77 0.3 1.79e-8 Renal function-related traits (BUN); LIHC cis rs9640161 0.830 rs3757424 chr7:150067679 C/A cg10018233 chr7:150070692 REPIN1 0.7 13.19 0.58 2.05e-32 Blood protein levels;Circulating chemerin levels; LIHC cis rs6545883 0.831 rs9309336 chr2:61763165 T/C cg14146966 chr2:61757674 XPO1 0.47 8.2 0.41 4.75e-15 Tuberculosis; LIHC cis rs644799 1.000 rs12291986 chr11:95523030 T/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.85 0.3 1.17e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs5769765 0.908 rs9616211 chr22:50317676 G/A cg09182678 chr22:50328711 NA -0.41 -6.08 -0.31 3.15e-9 Schizophrenia; LIHC cis rs992157 0.700 rs10165153 chr2:219159629 T/C cg20019365 chr2:219134978 PNKD;AAMP 0.78 12.51 0.56 8.22e-30 Colorectal cancer; LIHC cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.39 5.89 0.3 9.11e-9 Schizophrenia; LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg00656387 chr3:40428638 ENTPD3 0.49 8.25 0.41 3.48e-15 Renal cell carcinoma; LIHC cis rs35306767 0.714 rs66797613 chr10:1090469 C/T cg26597838 chr10:835615 NA 0.77 7.44 0.37 7.95e-13 Eosinophil percentage of granulocytes; LIHC cis rs79149102 0.579 rs7179097 chr15:75279240 T/G cg09165964 chr15:75287851 SCAMP5 -0.56 -7.56 -0.38 3.74e-13 Lung cancer; LIHC cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg23758822 chr17:41437982 NA 0.92 17.02 0.68 1.74e-47 Menopause (age at onset); LIHC cis rs4631830 0.900 rs7914347 chr10:51537431 C/T cg20129853 chr10:51489980 NA -0.4 -8.66 -0.42 1.92e-16 Prostate-specific antigen levels; LIHC cis rs7582180 0.629 rs12621892 chr2:100947124 G/C cg14675211 chr2:100938903 LONRF2 0.56 8.96 0.44 2.2e-17 Intelligence (multi-trait analysis); LIHC cis rs3106136 0.807 rs9997915 chr4:95278027 C/T cg11021082 chr4:95130006 SMARCAD1 0.38 6.56 0.33 2.02e-10 Capecitabine sensitivity; LIHC cis rs611744 0.538 rs13257548 chr8:109273185 G/A cg18478394 chr8:109455254 TTC35 0.39 6.64 0.34 1.24e-10 Dupuytren's disease; LIHC cis rs9649213 0.613 rs7777415 chr7:97959214 A/T cg08684580 chr7:98029266 BAIAP2L1 -0.39 -6.06 -0.31 3.62e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17228093 chr9:37651075 FRMPD1 0.45 6.68 0.34 9.42e-11 Alopecia areata; LIHC cis rs2795502 0.882 rs3123754 chr10:43339011 G/A cg20628663 chr10:43360327 NA -0.47 -7.32 -0.37 1.76e-12 Blood protein levels; LIHC cis rs7677751 0.747 rs1800809 chr4:55093914 A/G cg17187183 chr4:55093834 PDGFRA 0.68 8.53 0.42 4.89e-16 Corneal astigmatism; LIHC cis rs35883536 0.545 rs56674564 chr1:101097718 T/C cg14515779 chr1:101123966 NA -0.6 -11.37 -0.52 1.21e-25 Monocyte count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22753607 chr9:37120306 ZCCHC7 0.41 6.36 0.33 6.54e-10 Cognitive function; LIHC cis rs6450176 0.564 rs381024 chr5:53326234 G/A ch.5.1024479R chr5:53302184 ARL15 -0.75 -13.59 -0.59 6.42e-34 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6539267 0.741 rs10861572 chr12:106688576 A/G cg02476566 chr12:106696527 TCP11L2 -0.46 -6.12 -0.31 2.61e-9 Tourette syndrome; LIHC trans rs208520 1.000 rs208529 chr6:66957549 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.68 -0.34 9.52e-11 Exhaled nitric oxide output; LIHC cis rs1005277 0.579 rs116912400 chr10:38479207 G/T cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1395 1.000 rs1141313 chr2:27460968 A/G cg23587288 chr2:27483067 SLC30A3 -0.3 -5.87 -0.3 1.04e-8 Blood metabolite levels; LIHC cis rs6088590 1.000 rs6119512 chr20:33306904 T/C cg24642439 chr20:33292090 TP53INP2 0.8 11.61 0.53 1.66e-26 Coronary artery disease; LIHC cis rs7904368 0.568 rs10752061 chr10:16853900 A/G cg23933602 chr10:16859644 RSU1 0.56 9.9 0.47 1.73e-20 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs12365397 1.000 rs11037360 chr11:43239804 G/A cg16667275 chr11:43333495 API5 0.44 6.0 0.31 5.15e-9 Migraine; LIHC cis rs2153535 0.580 rs1414344 chr6:8471365 C/A cg23788917 chr6:8435910 SLC35B3 0.59 8.42 0.41 1.06e-15 Motion sickness; LIHC cis rs4820294 0.669 rs9622678 chr22:38057338 A/G cg26138144 chr22:38071188 LGALS1 0.42 7.88 0.39 4.48e-14 Fat distribution (HIV); LIHC cis rs9911578 1.000 rs11869828 chr17:56609525 G/A cg05425664 chr17:57184151 TRIM37 0.59 8.8 0.43 6.73e-17 Intelligence (multi-trait analysis); LIHC cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg23172400 chr8:95962367 TP53INP1 -0.38 -8.4 -0.41 1.22e-15 Type 2 diabetes; LIHC cis rs10540 1.000 rs35255804 chr11:492617 G/A cg03352830 chr11:487213 PTDSS2 0.82 6.88 0.35 2.87e-11 Body mass index; LIHC cis rs5753618 0.539 rs737888 chr22:31611549 A/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.6 -0.38 2.96e-13 Colorectal cancer; LIHC cis rs9560113 1.000 rs9560105 chr13:112175363 A/T cg14154082 chr13:112174009 NA -0.28 -5.92 -0.3 7.77e-9 Menarche (age at onset); LIHC cis rs644148 0.834 rs2461535 chr19:45000875 C/T cg15540054 chr19:45004280 ZNF180 -0.71 -10.55 -0.5 1.01e-22 Personality dimensions; LIHC trans rs561341 0.882 rs111484028 chr17:30287701 G/A cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 8.04e-24 Hip circumference adjusted for BMI; LIHC cis rs10779751 0.734 rs2791657 chr1:11128001 A/G cg08854313 chr1:11322531 MTOR 0.69 10.18 0.48 1.93e-21 Body mass index; LIHC cis rs933688 0.938 rs1477348 chr5:90707823 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.61 0.67 7.88e-46 Smoking behavior; LIHC cis rs2153535 0.580 rs6597335 chr6:8527714 T/C cg23788917 chr6:8435910 SLC35B3 0.64 9.08 0.44 8.77e-18 Motion sickness; LIHC cis rs1355223 0.583 rs2941057 chr11:34882220 G/A cg24088639 chr11:34937564 PDHX;APIP -0.38 -5.96 -0.31 6.21e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11628318 0.614 rs1190337 chr14:103106159 A/C cg01864069 chr14:103024347 NA -0.45 -7.12 -0.36 6.24e-12 Platelet count; LIHC cis rs3796352 0.667 rs34860124 chr3:52857778 T/A cg04865290 chr3:52927548 TMEM110 -0.44 -5.8 -0.3 1.5e-8 Immune reponse to smallpox (secreted IL-2); LIHC trans rs11098499 0.865 rs11722183 chr4:120280597 A/C cg25214090 chr10:38739885 LOC399744 0.55 8.61 0.42 2.69e-16 Corneal astigmatism; LIHC cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg00106254 chr7:1943704 MAD1L1 -0.37 -5.86 -0.3 1.09e-8 Schizophrenia; LIHC cis rs17106184 0.536 rs12083078 chr1:51066950 A/T cg07174182 chr1:51127561 FAF1 0.45 5.85 0.3 1.12e-8 Type 2 diabetes; LIHC cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.18e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs422249 0.547 rs174533 chr11:61549025 G/A cg27386326 chr11:61587980 NA 0.7 14.64 0.62 5.17e-38 Trans fatty acid levels; LIHC cis rs17125944 0.615 rs7151474 chr14:53313680 C/T cg00686598 chr14:53173677 PSMC6 -0.84 -9.92 -0.47 1.47e-20 Alzheimer's disease (late onset); LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg26338869 chr17:61819248 STRADA 0.62 8.93 0.43 2.74e-17 Prudent dietary pattern; LIHC cis rs6952808 0.595 rs3800916 chr7:2166072 C/T cg02951883 chr7:2050386 MAD1L1 -0.64 -10.54 -0.5 1.14e-22 Bipolar disorder and schizophrenia; LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg18306943 chr3:40428807 ENTPD3 0.43 7.58 0.38 3.19e-13 Renal cell carcinoma; LIHC trans rs916888 0.773 rs199457 chr17:44795469 C/T cg07870213 chr5:140052090 DND1 1.04 10.68 0.5 3.72e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1401999 0.674 rs562 chr3:183637845 T/C cg01324343 chr3:183735012 ABCC5 0.53 8.31 0.41 2.29e-15 Anterior chamber depth; LIHC cis rs10791097 0.694 rs4264159 chr11:130755784 G/T cg12179176 chr11:130786555 SNX19 0.85 13.92 0.6 3.24e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1799949 0.859 rs11657004 chr17:41442751 A/G cg23758822 chr17:41437982 NA 0.94 17.57 0.69 1.04e-49 Menopause (age at onset); LIHC cis rs6952808 0.600 rs2895202 chr7:2131829 T/C cg21782813 chr7:2030301 MAD1L1 0.37 6.29 0.32 9.86e-10 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg07677032 chr17:61819896 STRADA 0.48 6.93 0.35 2.05e-11 Prudent dietary pattern; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg14868726 chr18:2571660 METTL4;NDC80 0.4 6.13 0.31 2.49e-9 Metabolic traits; LIHC trans rs7618501 0.735 rs9876508 chr3:49780844 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.555 rs11610015 chr12:38508856 A/G cg13010199 chr12:38710504 ALG10B 0.44 6.17 0.32 1.96e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs9549367 0.713 rs3024745 chr13:113821598 A/G cg00898013 chr13:113819073 PROZ -0.44 -7.08 -0.36 8.33e-12 Platelet distribution width; LIHC cis rs11673344 0.764 rs826304 chr19:37443583 T/G cg27390819 chr19:37464633 NA -0.53 -6.38 -0.33 5.74e-10 Obesity-related traits; LIHC cis rs709400 0.658 rs72708874 chr14:103899251 T/G cg26031613 chr14:104095156 KLC1 0.78 10.21 0.48 1.54e-21 Body mass index; LIHC cis rs2153535 0.541 rs6923558 chr6:8461467 T/G cg21535247 chr6:8435926 SLC35B3 0.63 8.15 0.4 6.78e-15 Motion sickness; LIHC cis rs9790314 0.586 rs34727114 chr3:161138929 A/C cg17135325 chr3:160939158 NMD3 0.51 7.5 0.38 5.44e-13 Morning vs. evening chronotype; LIHC cis rs1707322 0.717 rs1135812 chr1:46095272 T/C cg06784218 chr1:46089804 CCDC17 0.42 7.74 0.39 1.12e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6684514 1.000 rs2273832 chr1:156233143 A/G cg16558208 chr1:156270281 VHLL 0.53 9.63 0.46 1.35e-19 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg12311346 chr5:56204834 C5orf35 0.6 7.54 0.38 4.35e-13 Initial pursuit acceleration; LIHC cis rs8141529 0.764 rs5752812 chr22:29225603 T/A cg02153584 chr22:29168773 CCDC117 0.58 9.27 0.45 2.11e-18 Lymphocyte counts; LIHC cis rs9896052 0.608 rs9797247 chr17:73445814 C/T cg25649188 chr17:73499917 CASKIN2 0.42 6.62 0.34 1.42e-10 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs734999 0.545 rs6666430 chr1:2698950 G/A cg18854424 chr1:2615690 NA 0.34 7.32 0.37 1.8e-12 Ulcerative colitis; LIHC cis rs7618501 1.000 rs7374277 chr3:49784777 T/C cg24110177 chr3:50126178 RBM5 0.42 6.47 0.33 3.43e-10 Intelligence (multi-trait analysis); LIHC cis rs9911578 0.967 rs4132925 chr17:56938016 C/G cg05425664 chr17:57184151 TRIM37 0.6 8.85 0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs2066819 1.000 rs41423244 chr12:56693520 A/C cg26734620 chr12:56694298 CS -1.3 -11.32 -0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs11871801 0.517 rs6963 chr17:40731597 A/T cg14558262 chr17:40713999 COASY -0.61 -9.48 -0.46 4.24e-19 Crohn's disease; LIHC cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg02290350 chr8:58132656 NA 0.47 9.33 0.45 1.38e-18 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg25072359 chr17:41440525 NA 0.38 6.02 0.31 4.57e-9 Menopause (age at onset); LIHC cis rs507080 0.922 rs558907 chr11:118558455 A/G cg04173919 chr11:118528438 PHLDB1 0.35 6.59 0.34 1.65e-10 Serum metabolite levels; LIHC cis rs7572733 0.555 rs7420608 chr2:198915930 A/T cg00792783 chr2:198669748 PLCL1 0.4 5.79 0.3 1.57e-8 Dermatomyositis; LIHC cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs1865760 0.508 rs9379820 chr6:26049924 T/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.74 0.3 2.07e-8 Height; LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg24209194 chr3:40518798 ZNF619 0.55 8.06 0.4 1.34e-14 Renal cell carcinoma; LIHC trans rs877282 0.583 rs112372193 chr10:826602 A/G cg22713356 chr15:30763199 NA 0.82 7.25 0.36 2.72e-12 Uric acid levels; LIHC cis rs12478296 0.892 rs11897561 chr2:243014976 C/A cg06360820 chr2:242988706 NA -0.79 -11.66 -0.53 1.09e-26 Obesity-related traits; LIHC cis rs17253792 0.732 rs10146604 chr14:56045770 C/G cg24579896 chr14:56047964 C14orf33;KTN1 0.7 5.82 0.3 1.38e-8 Putamen volume; LIHC cis rs4819052 0.851 rs2838848 chr21:46671017 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.77 0.39 9.12e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7224314 1.000 rs6504503 chr17:65386690 A/T cg01507342 chr17:65387096 PITPNC1 -0.5 -6.27 -0.32 1.07e-9 Diisocyanate-induced asthma; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg02993280 chr1:107599747 PRMT6 0.65 10.58 0.5 8.35e-23 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs1814175 0.588 rs1721994 chr11:49914050 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs10540 1.000 rs79808876 chr11:465763 C/A cg03576123 chr11:487126 PTDSS2 -1.0 -8.14 -0.4 7.3e-15 Body mass index; LIHC cis rs7647973 1.000 rs3448 chr3:49396751 T/C cg07636037 chr3:49044803 WDR6 0.53 6.43 0.33 4.31e-10 Menarche (age at onset); LIHC cis rs2050392 0.517 rs160018 chr10:30772703 T/C cg25182066 chr10:30743637 MAP3K8 -0.66 -10.54 -0.5 1.12e-22 Inflammatory bowel disease; LIHC cis rs7582720 0.943 rs115628302 chr2:203690047 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9311474 0.575 rs4434138 chr3:52556890 A/G cg10802521 chr3:52805072 NEK4 -0.4 -6.62 -0.34 1.38e-10 Electroencephalogram traits; LIHC cis rs10540 0.915 rs35389167 chr11:460765 A/G cg26566283 chr11:622021 MUPCDH -0.72 -5.93 -0.31 7.41e-9 Body mass index; LIHC cis rs1046896 0.739 rs2379358 chr17:80741612 G/A cg00809820 chr17:80708513 TBCD;FN3K 0.36 6.2 0.32 1.59e-9 Glycated hemoglobin levels; LIHC cis rs10832963 0.847 rs4237722 chr11:18639363 T/C cg20219074 chr11:18656078 SPTY2D1 0.82 13.04 0.58 7.63e-32 Breast cancer; LIHC cis rs3020736 0.500 rs9620026 chr22:42498578 C/T cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs34330 0.562 rs7486387 chr12:12866911 G/A cg04607235 chr12:12878440 APOLD1 -0.76 -9.29 -0.45 1.81e-18 Systemic lupus erythematosus; LIHC cis rs8180040 0.966 rs60369822 chr3:47479735 A/C cg27129171 chr3:47204927 SETD2 -0.56 -9.45 -0.46 5.33e-19 Colorectal cancer; LIHC cis rs9549367 0.713 rs1323315 chr13:113859658 T/C cg00898013 chr13:113819073 PROZ 0.35 6.3 0.32 9.37e-10 Platelet distribution width; LIHC cis rs644799 0.610 rs1255179 chr11:95472097 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.61 10.35 0.49 4.94e-22 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs801193 0.569 rs2707824 chr7:66189243 A/G cg18876405 chr7:65276391 NA 0.32 5.92 0.3 7.87e-9 Aortic root size; LIHC cis rs2839186 0.814 rs2839167 chr21:47661587 A/G cg12016809 chr21:47604291 C21orf56 0.45 6.86 0.35 3.28e-11 Testicular germ cell tumor; LIHC cis rs4803468 1.000 rs4803465 chr19:41918158 A/G cg14132834 chr19:41945861 ATP5SL 0.43 6.31 0.32 8.78e-10 Height; LIHC cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC cis rs2033711 0.728 rs4801586 chr19:58934528 A/G cg26874164 chr19:58962979 ZNF324B 0.44 6.1 0.31 2.91e-9 Uric acid clearance; LIHC cis rs600806 0.751 rs7551176 chr1:109961965 C/T cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.19 -0.36 4.04e-12 Intelligence (multi-trait analysis); LIHC trans rs875971 0.545 rs17138149 chr7:65693180 A/G cg26939375 chr7:64535504 NA 0.41 6.58 0.34 1.8e-10 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10900048 chr4:73935377 COX18 0.47 6.06 0.31 3.62e-9 Lung function (FEV1/FVC); LIHC cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg16262614 chr3:133464971 TF 0.28 6.23 0.32 1.36e-9 Iron status biomarkers; LIHC cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9942416 0.660 rs193344 chr5:74977854 T/C cg19683494 chr5:74908142 NA -0.54 -7.2 -0.36 3.86e-12 Age-related disease endophenotypes; LIHC cis rs2033711 0.755 rs4801587 chr19:58936679 C/A cg13877915 chr19:58951672 ZNF132 0.57 8.73 0.43 1.11e-16 Uric acid clearance; LIHC cis rs9326248 0.520 rs6589602 chr11:117037065 T/C cg01368799 chr11:117014884 PAFAH1B2 0.67 10.3 0.49 7.28e-22 Blood protein levels; LIHC cis rs651907 0.557 rs13077925 chr3:101488181 T/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.5 0.49 1.6e-22 Colorectal cancer; LIHC cis rs2242116 0.796 rs7623898 chr3:46974172 C/T cg16586182 chr3:47516702 SCAP 0.4 6.71 0.34 8.29e-11 Birth weight; LIHC cis rs9611565 0.694 rs11090056 chr22:42095904 A/C cg03806693 chr22:41940476 POLR3H 0.8 9.07 0.44 9.78e-18 Vitiligo; LIHC cis rs5758511 0.680 rs5758688 chr22:42662501 T/C cg00645731 chr22:42541494 CYP2D7P1 0.53 8.55 0.42 4.12e-16 Birth weight; LIHC cis rs2292884 0.505 rs77856818 chr2:238402830 G/A cg08992911 chr2:238395768 MLPH 0.63 6.41 0.33 4.69e-10 Prostate cancer; LIHC cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg00166722 chr3:10149974 C3orf24 0.52 5.93 0.31 7.23e-9 Alzheimer's disease; LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.06e-19 Renal cell carcinoma; LIHC cis rs5771242 0.769 rs4838865 chr22:50664612 A/G cg16473166 chr22:50639996 SELO 0.5 5.81 0.3 1.45e-8 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); LIHC cis rs4713118 0.513 rs9368547 chr6:28028067 A/G cg23485639 chr6:28045615 ZNF165 0.38 5.77 0.3 1.75e-8 Parkinson's disease; LIHC cis rs2050392 0.624 rs303449 chr10:30726845 G/A cg18806716 chr10:30721971 MAP3K8 -0.42 -5.99 -0.31 5.22e-9 Inflammatory bowel disease; LIHC cis rs2625529 0.824 rs12916951 chr15:72252498 C/T cg16672083 chr15:72433130 SENP8 -0.3 -5.92 -0.31 7.64e-9 Red blood cell count; LIHC cis rs12701220 0.817 rs7798459 chr7:1087965 C/T cg04025307 chr7:1156635 C7orf50 0.45 6.13 0.31 2.48e-9 Bronchopulmonary dysplasia; LIHC cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg07424592 chr7:64974309 NA -0.68 -8.2 -0.41 4.92e-15 Diabetic kidney disease; LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg22528358 chr1:107598549 PRMT6 -0.69 -11.54 -0.53 3e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7572733 0.514 rs700686 chr2:198721054 G/A cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs6594499 0.872 rs2112541 chr5:110449346 T/C cg04022379 chr5:110408740 TSLP 0.5 8.29 0.41 2.64e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs8062405 0.965 rs7359397 chr16:28885659 C/T cg00204512 chr16:28754710 NA 0.36 6.43 0.33 4.28e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs798554 0.757 rs1182171 chr7:2878510 A/G cg13628971 chr7:2884303 GNA12 0.49 6.84 0.35 3.64e-11 Height; LIHC cis rs826838 1.000 rs11168217 chr12:38884278 T/C cg26384229 chr12:38710491 ALG10B 0.98 13.3 0.58 7.84e-33 Heart rate; LIHC cis rs1664789 0.836 rs702638 chr5:53268072 T/C ch.5.1024479R chr5:53302184 ARL15 0.46 7.23 0.36 3.28e-12 Waist circumference adjusted for body mass index; LIHC cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg18230493 chr5:56204884 C5orf35 -0.47 -6.61 -0.34 1.5e-10 Initial pursuit acceleration; LIHC cis rs9341808 0.556 rs2223875 chr6:81045452 C/T cg08355045 chr6:80787529 NA 0.33 6.77 0.34 5.6e-11 Sitting height ratio; LIHC cis rs694739 0.892 rs647152 chr11:64109118 T/G cg02228329 chr11:64053129 BAD;GPR137 0.57 8.37 0.41 1.54e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs4650994 0.507 rs12141152 chr1:178514165 C/T cg05059571 chr16:84539110 KIAA1609 -0.45 -7.45 -0.37 7.89e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7020830 0.830 rs12554976 chr9:37244505 G/T cg14294708 chr9:37120828 ZCCHC7 1.11 23.43 0.78 4.25e-73 Schizophrenia; LIHC cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg12463550 chr7:65579703 CRCP -0.66 -6.85 -0.35 3.41e-11 Diabetic kidney disease; LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.56 8.36 0.41 1.66e-15 Height; LIHC cis rs6088590 1.000 rs6119535 chr20:33442138 A/C cg24642439 chr20:33292090 TP53INP2 0.74 9.84 0.47 2.81e-20 Coronary artery disease; LIHC cis rs7534824 0.625 rs7414132 chr1:101526413 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.69 7.19 0.36 4.14e-12 Refractive astigmatism; LIHC cis rs72627509 0.857 rs781658 chr4:57779567 G/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.54 -7.92 -0.39 3.41e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs561341 0.714 rs111760509 chr17:30304320 A/G cg20587970 chr11:113659929 NA -1.39 -11.79 -0.54 3.68e-27 Hip circumference adjusted for BMI; LIHC cis rs6867032 0.527 rs1017924 chr5:1976187 C/T cg26168224 chr5:2018326 NA 0.25 5.78 0.3 1.7e-8 Gut microbiome composition (winter); LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg04267008 chr7:1944627 MAD1L1 -0.63 -10.19 -0.48 1.77e-21 Bipolar disorder and schizophrenia; LIHC cis rs7635838 0.892 rs6792718 chr3:11434380 A/G cg00170343 chr3:11313890 ATG7 0.43 6.87 0.35 3.04e-11 HDL cholesterol; LIHC cis rs62179067 0.708 rs76035073 chr2:179940750 C/T cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg13393036 chr8:95962371 TP53INP1 -0.4 -8.98 -0.44 1.88e-17 Type 2 diabetes; LIHC cis rs477895 0.713 rs12787852 chr11:63954648 G/A cg18225595 chr11:63971243 STIP1 0.69 8.53 0.42 4.92e-16 Mean platelet volume; LIHC cis rs6665290 0.669 rs12406714 chr1:227177061 T/C cg10327440 chr1:227177885 CDC42BPA -1.12 -24.08 -0.79 1.29e-75 Myeloid white cell count; LIHC cis rs2580764 0.624 rs12713284 chr2:55228861 G/A cg09592903 chr2:55203963 RTN4 -0.73 -13.53 -0.59 1.1e-33 Mean platelet volume; LIHC cis rs4845570 1.000 rs3811415 chr1:151763767 C/T cg07092448 chr1:151763213 TDRKH -0.69 -7.1 -0.36 7.42e-12 Coronary artery disease; LIHC cis rs7927592 0.913 rs7116994 chr11:68254627 C/T cg01657329 chr11:68192670 LRP5 -0.45 -5.94 -0.31 6.95e-9 Total body bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15563057 chr5:139493612 PURA 0.4 6.33 0.32 7.53e-10 Cognitive function; LIHC cis rs9325144 0.647 rs61937754 chr12:39060543 T/C cg26384229 chr12:38710491 ALG10B -0.42 -5.94 -0.31 6.88e-9 Morning vs. evening chronotype; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14108327 chr4:890186 GAK 0.39 6.21 0.32 1.55e-9 Bilirubin levels; LIHC cis rs2354432 0.607 rs57078845 chr1:146722222 G/A cg25205988 chr1:146714368 CHD1L -0.91 -10.96 -0.51 3.59e-24 Mitochondrial DNA levels; LIHC cis rs8108269 1.000 rs10421259 chr19:46158860 G/A cg13320842 chr19:46175254 GIPR 0.41 7.7 0.38 1.5e-13 Type 2 diabetes; LIHC cis rs644799 0.965 rs11021317 chr11:95517576 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.75 0.69 1.98e-50 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs77637988 0.578 rs11683099 chr2:48611519 A/T cg00032884 chr2:48540671 FOXN2 0.38 5.88 0.3 9.61e-9 Joint mobility (Beighton score); LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg07677032 chr17:61819896 STRADA 0.44 6.33 0.32 7.68e-10 Prudent dietary pattern; LIHC cis rs892961 0.932 rs12452788 chr17:75406866 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.39 0.37 1.15e-12 Airflow obstruction; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03113475 chr19:12833063 TNPO2 0.47 6.27 0.32 1.11e-9 Lung function (FEV1/FVC); LIHC cis rs9918079 0.560 rs10008376 chr4:15623955 A/G cg21329975 chr4:15471214 CC2D2A 0.39 5.85 0.3 1.13e-8 Obesity-related traits; LIHC cis rs4713118 0.955 rs9380012 chr6:27684654 A/G cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC trans rs561341 0.714 rs75861674 chr17:30304317 A/G cg20587970 chr11:113659929 NA -1.22 -10.54 -0.5 1.08e-22 Hip circumference adjusted for BMI; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.76 -0.34 6.07e-11 Total body bone mineral density; LIHC cis rs847649 0.692 rs6969054 chr7:102446569 T/C cg18108683 chr7:102477205 FBXL13 -0.51 -7.83 -0.39 6.02e-14 Morning vs. evening chronotype; LIHC cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg22105103 chr4:187893119 NA -0.34 -8.28 -0.41 2.73e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs6918586 0.658 rs198809 chr6:26128766 G/A cg18357526 chr6:26021779 HIST1H4A -0.58 -8.71 -0.43 1.3e-16 Schizophrenia; LIHC cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.82 0.35 4.1e-11 Gut microbiome composition (summer); LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg24846343 chr22:24311635 DDTL 0.62 11.5 0.53 4.22e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7616330 0.895 rs7615404 chr3:71045288 T/C cg01511742 chr3:71112437 FOXP1 -0.45 -6.21 -0.32 1.54e-9 QT interval; LIHC cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg21280719 chr6:42927975 GNMT -0.36 -7.72 -0.39 1.29e-13 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1003719 0.688 rs2835662 chr21:38568967 T/A cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11777290 chr7:64535486 NA 0.45 6.28 0.32 1.05e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6459788 0.693 rs35146559 chr7:157238557 G/A cg06271696 chr7:157225062 NA -0.49 -7.88 -0.39 4.37e-14 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs74233809 1.000 rs943037 chr10:104835919 C/T cg03493300 chr10:104813866 CNNM2 0.47 6.19 0.32 1.68e-9 Birth weight; LIHC cis rs3096299 0.933 rs889576 chr16:89429653 A/G cg00750074 chr16:89608354 SPG7 0.4 6.23 0.32 1.37e-9 Multiple myeloma (IgH translocation); LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.58 -8.19 -0.41 5.12e-15 Lymphocyte counts; LIHC cis rs11583043 0.874 rs6577222 chr1:101420502 C/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.8 0.3 1.48e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs875971 1.000 rs55962648 chr7:65625751 C/G cg18876405 chr7:65276391 NA -0.38 -6.88 -0.35 2.82e-11 Aortic root size; LIHC cis rs12472274 0.817 rs12621791 chr2:239104061 G/A cg17459225 chr2:239074497 NA 0.78 12.95 0.57 1.68e-31 Phospholipid levels (plasma); LIHC cis rs9837602 0.507 rs1718244 chr3:99512608 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.91 0.35 2.42e-11 Breast cancer; LIHC cis rs7917772 0.636 rs7897384 chr10:104529042 T/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -5.8 -0.3 1.55e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs12908161 1.000 rs35524990 chr15:85258203 T/C cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs929354 0.713 rs6459733 chr7:156930550 G/C cg17757837 chr7:157058334 UBE3C 0.7 11.36 0.52 1.34e-25 Body mass index; LIHC cis rs992157 0.764 rs10932774 chr2:219191569 A/G cg00012203 chr2:219082015 ARPC2 0.72 10.4 0.49 3.3e-22 Colorectal cancer; LIHC cis rs9733 0.818 rs11204695 chr1:150657011 T/G cg13175981 chr1:150552382 MCL1 0.52 8.12 0.4 8.36e-15 Tonsillectomy; LIHC cis rs17639215 0.550 rs9679297 chr2:102914569 T/C cg09003973 chr2:102972529 NA 0.61 6.09 0.31 3.04e-9 Serum protein levels (sST2); LIHC cis rs360798 0.553 rs11682530 chr2:63073194 C/T cg17519650 chr2:63277830 OTX1 -0.55 -8.36 -0.41 1.56e-15 Coronary artery disease; LIHC cis rs9790314 1.000 rs4370045 chr3:160943865 A/G cg03342759 chr3:160939853 NMD3 -0.73 -9.2 -0.45 3.52e-18 Morning vs. evening chronotype; LIHC cis rs6546550 0.935 rs4853027 chr2:70039224 A/G cg02498382 chr2:70120550 SNRNP27 0.38 6.29 0.32 9.75e-10 Prevalent atrial fibrillation; LIHC cis rs11711311 1.000 rs11711311 chr3:113430599 T/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.23 0.45 2.98e-18 IgG glycosylation; LIHC cis rs172166 0.694 rs536704 chr6:28092603 T/G cg23485639 chr6:28045615 ZNF165 0.4 6.26 0.32 1.16e-9 Cardiac Troponin-T levels; LIHC cis rs7592578 0.639 rs13417431 chr2:191293055 A/G cg10560079 chr2:191398806 TMEM194B -0.78 -11.26 -0.52 3.07e-25 Diastolic blood pressure; LIHC cis rs2239815 0.515 rs5762849 chr22:29238086 G/A cg15103426 chr22:29168792 CCDC117 0.43 5.81 0.3 1.39e-8 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.08 0.55 3.27e-28 Prudent dietary pattern; LIHC cis rs79976124 0.837 rs11751145 chr6:66642039 T/C cg07460842 chr6:66804631 NA 0.66 7.18 0.36 4.46e-12 Type 2 diabetes; LIHC cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs8177179 0.967 rs4078166 chr3:133435979 C/A cg18769074 chr3:133464867 TF 0.26 5.9 0.3 8.79e-9 Iron status biomarkers (transferrin levels); LIHC cis rs7677751 0.806 rs7678144 chr4:55102425 T/C cg17187183 chr4:55093834 PDGFRA 0.68 8.57 0.42 3.53e-16 Corneal astigmatism; LIHC cis rs78456975 0.574 rs13412980 chr2:1545231 C/A cg01028140 chr2:1542097 TPO -0.58 -7.62 -0.38 2.59e-13 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs12887734 0.546 rs66676135 chr14:104271504 G/A cg01849466 chr14:104193079 ZFYVE21 -0.4 -6.0 -0.31 4.96e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs8062405 1.000 rs8062405 chr16:28837906 C/T cg00204512 chr16:28754710 NA -0.34 -6.29 -0.32 9.64e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs860626 0.583 rs855767 chr10:119316080 C/T cg10846980 chr10:119306025 EMX2;EMX2OS -0.52 -7.92 -0.39 3.3e-14 Neuroticism; LIHC cis rs6963495 0.818 rs73192124 chr7:105171528 C/T cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs11190604 1.000 rs2495736 chr10:102338410 T/C cg07080220 chr10:102295463 HIF1AN 0.54 7.59 0.38 3e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs611744 0.967 rs637626 chr8:109235785 G/T cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs1552244 0.608 rs7615408 chr3:10000186 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -6.83 -0.35 3.84e-11 Alzheimer's disease; LIHC cis rs1008375 0.898 rs9998130 chr4:17593905 A/G cg16339924 chr4:17578868 LAP3 0.58 7.54 0.38 4.15e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs595982 0.527 rs73061659 chr19:49373556 G/A cg15549821 chr19:49342101 PLEKHA4 -0.69 -6.46 -0.33 3.5e-10 Red cell distribution width; LIHC cis rs2797685 1.000 rs707467 chr1:7861684 A/C cg04725166 chr1:7887271 PER3 -0.4 -7.12 -0.36 6.46e-12 Crohn's disease; LIHC cis rs8067354 0.574 rs2531898 chr17:58012351 G/C cg13753209 chr17:57696993 CLTC 0.71 10.58 0.5 7.79e-23 Hemoglobin concentration; LIHC cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.27e-10 Diabetic kidney disease; LIHC cis rs2302190 0.882 rs8067183 chr17:56462023 G/A cg05425664 chr17:57184151 TRIM37 -0.46 -5.75 -0.3 1.93e-8 Vitamin D levels; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11504245 chr5:55128562 NA 0.4 6.25 0.32 1.22e-9 Immature fraction of reticulocytes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17695382 chr2:61697821 USP34 0.47 6.17 0.32 1.89e-9 Lung function (FEV1/FVC); LIHC cis rs9814567 0.963 rs36006513 chr3:134291913 T/A cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.86 0.3 1.08e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs61990749 0.597 rs10148373 chr14:78280199 A/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.55 -7.79 -0.39 8.06e-14 Fibroblast growth factor basic levels; LIHC cis rs9733 0.715 rs7534124 chr1:150739073 C/T cg13175981 chr1:150552382 MCL1 0.48 7.05 0.36 1.01e-11 Tonsillectomy; LIHC cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg26939375 chr7:64535504 NA 0.47 7.15 0.36 5.18e-12 Calcium levels; LIHC cis rs600806 0.888 rs652651 chr1:109844532 A/G cg16275483 chr1:110013120 SYPL2 -0.51 -6.17 -0.32 1.93e-9 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.550 rs1438307 chr2:136499166 A/C cg07305463 chr2:136567211 LCT -0.39 -7.35 -0.37 1.46e-12 Mosquito bite size; LIHC cis rs6679073 1.000 rs10494874 chr1:205754688 C/G cg23034840 chr1:205782522 SLC41A1 0.41 6.26 0.32 1.17e-9 Prostate-specific antigen levels; LIHC cis rs8141529 0.956 rs132539 chr22:29304253 C/T cg15103426 chr22:29168792 CCDC117 0.46 7.21 0.36 3.61e-12 Lymphocyte counts; LIHC cis rs2274273 0.868 rs6573007 chr14:55625938 T/G cg01864836 chr14:55583639 NA -0.42 -8.24 -0.41 3.64e-15 Protein biomarker; LIHC cis rs853679 0.517 rs17711344 chr6:28077602 A/G cg16479474 chr6:28041457 NA -0.42 -6.05 -0.31 3.73e-9 Depression; LIHC cis rs116248771 0.690 rs4459938 chr3:158406075 G/A cg16708174 chr3:158430962 RARRES1 0.49 6.53 0.33 2.32e-10 diarrhoeal disease at age 2; LIHC cis rs6545883 0.929 rs2264100 chr2:61670829 G/A cg14146966 chr2:61757674 XPO1 0.46 7.8 0.39 7.41e-14 Tuberculosis; LIHC cis rs72627123 0.867 rs78742875 chr14:74457214 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.46 0.42 8.11e-16 Morning vs. evening chronotype; LIHC cis rs7044106 0.762 rs4837790 chr9:123446325 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.77 0.39 9.04e-14 Hip circumference adjusted for BMI; LIHC cis rs1865760 0.929 rs9358896 chr6:25943197 C/A cg17691542 chr6:26056736 HIST1H1C 0.39 5.84 0.3 1.23e-8 Height; LIHC cis rs12477438 0.798 rs1580068 chr2:99649969 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -10.77 -0.5 1.69e-23 Chronic sinus infection; LIHC cis rs2115630 1.000 rs6496452 chr15:85372645 A/T cg12501888 chr15:85177176 SCAND2 -0.46 -7.09 -0.36 7.65e-12 P wave terminal force; LIHC cis rs4975709 0.610 rs4975706 chr5:1860365 G/T cg14773178 chr5:1868261 NA 0.27 7.06 0.36 9.08e-12 Cardiovascular disease risk factors; LIHC cis rs4718428 0.705 rs4718424 chr7:66376095 G/A cg18252515 chr7:66147081 NA -0.69 -9.54 -0.46 2.69e-19 Corneal structure; LIHC cis rs7552404 0.731 rs1493367 chr1:76344011 C/A cg10523679 chr1:76189770 ACADM -0.55 -6.44 -0.33 3.94e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8067354 0.645 rs72840522 chr17:57829992 G/A cg13753209 chr17:57696993 CLTC 0.73 11.52 0.53 3.71e-26 Hemoglobin concentration; LIHC cis rs1395 0.744 rs11126929 chr2:27472027 C/T cg22903471 chr2:27725779 GCKR 0.41 6.15 0.32 2.15e-9 Blood metabolite levels; LIHC cis rs11190604 1.000 rs4919466 chr10:102241213 T/C cg07080220 chr10:102295463 HIF1AN 0.51 7.24 0.36 2.99e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs11577318 0.853 rs7541333 chr1:26622889 C/T cg10402321 chr1:26617780 UBXN11 -0.38 -6.06 -0.31 3.63e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs12042938 0.507 rs1765778 chr1:231732356 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.58 -7.91 -0.39 3.61e-14 Neuranatomic and neurocognitive phenotypes; LIHC cis rs7726839 0.540 rs72705097 chr5:655067 G/A cg09021430 chr5:549028 NA -0.41 -8.36 -0.41 1.56e-15 Obesity-related traits; LIHC cis rs7408868 1.000 rs2074618 chr19:15276143 C/T cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.68e-8 Pulse pressure; LIHC cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg19626725 chr5:178986131 RUFY1 -0.38 -6.01 -0.31 4.65e-9 Lung cancer; LIHC trans rs6952808 0.723 rs4721287 chr7:2028663 A/C cg04565464 chr8:145669602 NFKBIL2 0.4 6.69 0.34 9.34e-11 Bipolar disorder and schizophrenia; LIHC cis rs798554 0.660 rs2527692 chr7:2856533 G/A cg19717773 chr7:2847554 GNA12 -0.43 -7.62 -0.38 2.58e-13 Height; LIHC cis rs10504073 0.584 rs10957337 chr8:49959027 G/T cg00325661 chr8:49890786 NA 0.34 7.65 0.38 2.03e-13 Blood metabolite ratios; LIHC cis rs1823913 1.000 rs4853563 chr2:192119534 G/A cg12404831 chr2:192114017 MYO1B -0.33 -6.58 -0.34 1.75e-10 Obesity-related traits; LIHC cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg16970926 chr12:29381810 FAR2 0.3 6.14 0.32 2.24e-9 QT interval; LIHC cis rs11098499 0.954 rs10031665 chr4:120422852 T/C cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC cis rs9611565 0.649 rs5751144 chr22:42128097 A/G cg03806693 chr22:41940476 POLR3H -0.79 -8.91 -0.43 2.99e-17 Vitiligo; LIHC cis rs17384381 1.000 rs12140170 chr1:85849723 G/A cg16011679 chr1:85725395 C1orf52 0.82 8.6 0.42 3e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs67478160 0.643 rs8003653 chr14:104298836 A/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.49 0.56 9.68e-30 Schizophrenia; LIHC cis rs2073499 0.935 rs74398439 chr3:50331927 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.67 7.57 0.38 3.45e-13 Schizophrenia; LIHC cis rs11167764 0.945 rs6878397 chr5:141474012 A/G cg23435118 chr5:141488016 NDFIP1 -0.43 -5.74 -0.3 2.06e-8 Crohn's disease; LIHC cis rs699 0.556 rs2478520 chr1:230867197 G/A cg07502417 chr1:230849801 AGT 0.31 6.56 0.33 1.95e-10 Coronary artery disease; LIHC cis rs2749592 0.513 rs9417249 chr10:37837155 C/T cg00409905 chr10:38381863 ZNF37A 0.47 7.74 0.39 1.12e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6977660 1.000 rs6977660 chr7:19805480 C/T cg07541023 chr7:19748670 TWISTNB 0.39 6.15 0.32 2.14e-9 Thyroid stimulating hormone; LIHC cis rs8058578 0.832 rs35969813 chr16:30714417 T/C cg02466173 chr16:30829666 NA -0.45 -6.88 -0.35 2.89e-11 Multiple myeloma; LIHC cis rs921968 0.541 rs3731867 chr2:219472734 G/A cg02176678 chr2:219576539 TTLL4 -0.56 -7.73 -0.39 1.25e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs523522 0.962 rs9040 chr12:120900274 C/T cg12219531 chr12:120966889 COQ5 0.66 12.73 0.57 1.22e-30 High light scatter reticulocyte count; LIHC cis rs711245 0.637 rs11894187 chr2:36781708 T/A cg15105969 chr2:36825350 FEZ2 0.49 5.85 0.3 1.16e-8 Height; LIHC trans rs2727020 0.656 rs7925524 chr11:49437542 G/A cg03929089 chr4:120376271 NA -0.7 -11.01 -0.51 2.47e-24 Coronary artery disease; LIHC cis rs7193541 0.684 rs9931225 chr16:74699293 T/C cg01733217 chr16:74700730 RFWD3 0.97 24.51 0.8 2.7e-77 Multiple myeloma; LIHC cis rs6708331 0.517 rs6743372 chr2:70352640 G/T cg01613454 chr2:70366299 NA 0.38 6.14 0.32 2.23e-9 Obesity-related traits; LIHC cis rs780096 0.587 rs6743819 chr2:27567407 G/T cg21248554 chr2:27665150 KRTCAP3 -0.42 -5.76 -0.3 1.9e-8 Total body bone mineral density; LIHC cis rs12477438 0.520 rs6717723 chr2:99756930 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC cis rs1023500 0.551 rs2859438 chr22:42466980 A/T cg00645731 chr22:42541494 CYP2D7P1 0.4 6.33 0.32 7.6e-10 Schizophrenia; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg01101903 chr2:240322401 HDAC4 -0.37 -6.35 -0.32 6.95e-10 Neuroblastoma; LIHC cis rs11690935 0.959 rs1474074 chr2:172659852 G/A cg13550731 chr2:172543902 DYNC1I2 -0.95 -18.12 -0.7 6.36e-52 Schizophrenia; LIHC trans rs526821 0.595 rs608964 chr11:55339266 G/A cg03929089 chr4:120376271 NA -0.45 -6.87 -0.35 3.05e-11 Pediatric bone mineral density (spine); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20385686 chr1:27024451 ARID1A 0.41 6.64 0.34 1.2e-10 Calcium levels; LIHC cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg13271783 chr10:134563150 INPP5A -0.6 -7.17 -0.36 4.71e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4665809 1.000 rs10048683 chr2:26320519 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.72 -9.02 -0.44 1.34e-17 Gut microbiome composition (summer); LIHC cis rs6584283 0.846 rs7917446 chr10:101286207 T/C cg17888390 chr10:101282816 NA -0.3 -5.77 -0.3 1.81e-8 Ulcerative colitis; LIHC cis rs17376456 0.757 rs10066431 chr5:93198204 A/G cg25358565 chr5:93447407 FAM172A 1.08 9.74 0.47 5.89e-20 Diabetic retinopathy; LIHC cis rs477692 0.673 rs7909964 chr10:131338714 T/C cg19680672 chr10:131412579 MGMT -0.39 -5.94 -0.31 7.15e-9 Response to temozolomide; LIHC cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg12463550 chr7:65579703 CRCP 0.68 6.99 0.35 1.42e-11 Diabetic kidney disease; LIHC cis rs8060686 0.545 rs8057119 chr16:68268836 C/T cg05110241 chr16:68378359 PRMT7 -0.56 -6.45 -0.33 3.81e-10 HDL cholesterol;Metabolic syndrome; LIHC trans rs4906332 1.000 rs12896612 chr14:103877868 A/G cg17675199 chr6:35436792 RPL10A 0.32 6.27 0.32 1.11e-9 Coronary artery disease; LIHC cis rs3857067 0.806 rs12507575 chr4:95114920 T/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs11166927 1.000 rs11778622 chr8:140805582 A/G cg16909799 chr8:140841666 TRAPPC9 0.52 8.56 0.42 3.76e-16 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs1997103 0.954 rs9649780 chr7:55411741 A/C cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs16828019 0.852 rs2268678 chr1:41511053 G/A cg03962019 chr1:41807865 NA 0.49 7.03 0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs637571 0.584 rs594689 chr11:65635559 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.49 -7.38 -0.37 1.21e-12 Eosinophil percentage of white cells; LIHC cis rs17253792 0.822 rs75995456 chr14:56073194 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs17001868 0.881 rs12484358 chr22:40774660 G/A cg07138101 chr22:40742427 ADSL 0.59 6.26 0.32 1.18e-9 Mammographic density (dense area); LIHC cis rs7647973 0.626 rs9870858 chr3:49769071 C/T cg03060546 chr3:49711283 APEH 0.58 6.72 0.34 7.66e-11 Menarche (age at onset); LIHC cis rs11608355 0.545 rs9943724 chr12:109902903 G/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs703842 1.000 rs3825079 chr12:58203354 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.25 0.61 1.74e-36 Multiple sclerosis; LIHC cis rs8180040 0.903 rs7636423 chr3:47309134 C/G cg27129171 chr3:47204927 SETD2 0.69 11.97 0.54 8.29e-28 Colorectal cancer; LIHC trans rs637571 0.522 rs493899 chr11:65747952 A/C cg17712092 chr4:129076599 LARP1B 0.73 12.86 0.57 3.9e-31 Eosinophil percentage of white cells; LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.7 11.33 0.52 1.76e-25 Height; LIHC cis rs10832963 1.000 rs11024739 chr11:18645843 A/C cg09201001 chr11:18656081 SPTY2D1 -0.93 -17.24 -0.68 2.22e-48 Breast cancer; LIHC cis rs3862260 0.509 rs3795663 chr1:120165187 G/A cg11530693 chr1:120165357 ZNF697 0.48 7.59 0.38 3.02e-13 Systemic lupus erythematosus; LIHC cis rs10751667 0.961 rs6597954 chr11:987677 G/A ch.11.42038R chr11:967971 AP2A2 0.59 10.91 0.51 5.7e-24 Alzheimer's disease (late onset); LIHC cis rs8180040 0.800 rs11921117 chr3:47294000 T/C cg16586182 chr3:47516702 SCAP 0.51 8.97 0.44 2.04e-17 Colorectal cancer; LIHC cis rs2836950 0.501 rs35994303 chr21:40686020 C/T cg06238570 chr21:40685208 BRWD1 -0.5 -8.09 -0.4 1.05e-14 Menarche (age at onset); LIHC cis rs3096299 0.559 rs9931073 chr16:89568513 G/C cg02187348 chr16:89574699 SPG7 0.51 7.82 0.39 6.78e-14 Multiple myeloma (IgH translocation); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08518329 chr2:20101943 TTC32 0.32 6.51 0.33 2.65e-10 Calcium levels; LIHC cis rs763121 0.853 rs5750668 chr22:39079964 T/C cg14440974 chr22:39074834 NA -0.45 -7.31 -0.37 1.9e-12 Menopause (age at onset); LIHC cis rs1873147 0.569 rs11071710 chr15:63309193 A/G cg05771511 chr15:63340396 TPM1 -0.44 -5.94 -0.31 7.01e-9 Orofacial clefts; LIHC cis rs6545883 0.965 rs2305156 chr2:61729268 T/C cg15711740 chr2:61764176 XPO1 -0.43 -6.15 -0.32 2.12e-9 Tuberculosis; LIHC cis rs9916302 0.861 rs8079590 chr17:37426201 T/C cg03013999 chr17:37608204 MED1 0.36 6.03 0.31 4.18e-9 Glomerular filtration rate (creatinine); LIHC cis rs1005277 0.541 rs1740741 chr10:38515334 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs72653721 1.000 rs2295599 chr6:10961454 C/A cg13562911 chr6:11044106 ELOVL2 0.49 6.85 0.35 3.48e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs6952808 0.636 rs6964522 chr7:1953523 C/T cg21782813 chr7:2030301 MAD1L1 0.44 7.54 0.38 4.37e-13 Bipolar disorder and schizophrenia; LIHC cis rs703842 0.616 rs10783851 chr12:58231155 A/G cg18357645 chr12:58087776 OS9 0.41 5.86 0.3 1.08e-8 Multiple sclerosis; LIHC cis rs9911578 0.967 rs4598970 chr17:57076893 T/A cg12560992 chr17:57184187 TRIM37 -0.97 -17.66 -0.69 4.55e-50 Intelligence (multi-trait analysis); LIHC cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg11941060 chr3:133502564 NA 0.4 5.81 0.3 1.39e-8 Iron status biomarkers; LIHC cis rs9858542 0.953 rs12330269 chr3:49513910 G/A cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg13271783 chr10:134563150 INPP5A -0.6 -7.19 -0.36 4.03e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6723226 0.806 rs2710606 chr2:32811909 A/G cg02381751 chr2:32503542 YIPF4 0.75 10.78 0.5 1.57e-23 Intelligence (multi-trait analysis); LIHC cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg09467607 chr2:36825704 FEZ2 0.6 9.58 0.46 2.02e-19 Height; LIHC cis rs7116495 1.000 rs3750908 chr11:71822401 A/G cg26138937 chr11:71823887 C11orf51 0.8 7.93 0.39 3.24e-14 Severe influenza A (H1N1) infection; LIHC cis rs4843747 0.671 rs8062855 chr16:88106941 T/C cg00677901 chr16:88017247 BANP 0.52 8.02 0.4 1.74e-14 Menopause (age at onset); LIHC cis rs10927875 0.619 rs2013019 chr1:16129320 T/C cg21385522 chr1:16154831 NA -0.73 -10.14 -0.48 2.67e-21 Dilated cardiomyopathy; LIHC cis rs4563143 0.514 rs55727361 chr19:29300415 A/T cg14983838 chr19:29218262 NA 0.44 6.49 0.33 3.06e-10 Methadone dose in opioid dependence; LIHC cis rs797680 0.822 rs2297707 chr1:93646207 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.87 -0.3 1.03e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs894734 0.535 rs2366143 chr12:54323256 G/A cg17410650 chr12:54324560 NA -0.42 -8.03 -0.4 1.63e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs4671400 0.571 rs4672428 chr2:61478497 C/T cg14146966 chr2:61757674 XPO1 -0.36 -5.71 -0.3 2.44e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs4638749 0.677 rs13414687 chr2:108806245 A/G cg06795125 chr2:108905320 SULT1C2 -0.29 -5.81 -0.3 1.42e-8 Blood pressure; LIHC cis rs10791323 0.569 rs10736608 chr11:133740048 C/T cg06766960 chr11:133703094 NA -0.41 -6.22 -0.32 1.49e-9 Childhood ear infection; LIHC cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg00091569 chr3:40428383 ENTPD3 0.39 6.75 0.34 6.28e-11 Renal cell carcinoma; LIHC cis rs13191362 0.935 rs13212137 chr6:163010261 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1008375 0.933 rs6847966 chr4:17634255 G/A cg16339924 chr4:17578868 LAP3 0.44 6.13 0.31 2.38e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2991971 0.782 rs10789463 chr1:45927848 C/A cg24296786 chr1:45957014 TESK2 -0.53 -8.26 -0.41 3.18e-15 High light scatter reticulocyte count; LIHC cis rs1005277 0.522 rs289643 chr10:37941494 T/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.54 -0.46 2.7e-19 Extrinsic epigenetic age acceleration; LIHC cis rs763121 0.853 rs2072796 chr22:39064230 A/G cg14440974 chr22:39074834 NA -0.44 -7.24 -0.36 2.91e-12 Menopause (age at onset); LIHC cis rs6754311 0.731 rs3769005 chr2:136603366 C/G cg07305463 chr2:136567211 LCT 0.38 7.46 0.37 7.41e-13 Mosquito bite size; LIHC cis rs6815814 0.847 rs11725309 chr4:38783848 T/C cg06935464 chr4:38784597 TLR10 0.56 9.12 0.44 6.51e-18 Breast cancer; LIHC cis rs2239547 0.522 rs2581815 chr3:52982159 C/G cg11645453 chr3:52864694 ITIH4 0.22 5.78 0.3 1.72e-8 Schizophrenia; LIHC cis rs2243480 1.000 rs160652 chr7:65538431 A/G cg07424592 chr7:64974309 NA 0.73 8.23 0.41 4.12e-15 Diabetic kidney disease; LIHC cis rs35306767 0.903 rs11253458 chr10:882843 T/C cg26597838 chr10:835615 NA 1.21 14.35 0.61 7.24e-37 Eosinophil percentage of granulocytes; LIHC cis rs4803468 0.967 rs1077856 chr19:41885221 T/C cg09537434 chr19:41945824 ATP5SL -0.98 -20.0 -0.73 1.85e-59 Height; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.37 -0.33 6.2e-10 Total body bone mineral density; LIHC cis rs509477 0.662 rs273343 chr18:32604173 G/C cg23791764 chr18:32556832 MAPRE2 0.47 6.41 0.33 4.85e-10 Cerebrospinal fluid AB1-42 levels; LIHC cis rs754466 0.958 rs58916802 chr10:79695870 G/A cg17075019 chr10:79541650 NA -0.59 -7.68 -0.38 1.69e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7107174 1.000 rs2511178 chr11:77923220 C/T cg02023728 chr11:77925099 USP35 0.46 8.49 0.42 6.6e-16 Testicular germ cell tumor; LIHC cis rs8180040 1.000 rs295442 chr3:47335881 A/C cg27129171 chr3:47204927 SETD2 0.64 11.24 0.52 3.84e-25 Colorectal cancer; LIHC cis rs986417 0.818 rs965455 chr14:60960314 A/C cg27398547 chr14:60952738 C14orf39 0.84 9.9 0.47 1.8e-20 Gut microbiota (bacterial taxa); LIHC cis rs801193 0.569 rs4717315 chr7:66178325 C/T cg18876405 chr7:65276391 NA 0.33 5.97 0.31 6.1e-9 Aortic root size; LIHC cis rs400736 0.860 rs2294890 chr1:8086527 T/G cg25007680 chr1:8021821 PARK7 0.6 9.5 0.46 3.91e-19 Response to antidepressants and depression; LIHC cis rs2404602 0.709 rs11072591 chr15:76649562 A/G cg23625390 chr15:77176239 SCAPER 0.47 7.86 0.39 5.17e-14 Blood metabolite levels; LIHC cis rs68170813 0.559 rs11769861 chr7:106979559 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.86 -0.3 1.08e-8 Coronary artery disease; LIHC cis rs4474465 0.688 rs7124803 chr11:78280822 T/G cg27205649 chr11:78285834 NARS2 0.5 7.83 0.39 6e-14 Alzheimer's disease (survival time); LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg06558623 chr16:89946397 TCF25 1.01 15.7 0.65 3.23e-42 Skin colour saturation; LIHC cis rs611744 0.550 rs1448154 chr8:109281053 T/C cg21045802 chr8:109455806 TTC35 0.59 10.39 0.49 3.75e-22 Dupuytren's disease; LIHC cis rs12079745 0.793 rs11805562 chr1:169292916 A/C cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -6.98 -0.35 1.51e-11 QT interval; LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.11 -0.31 2.76e-9 Total body bone mineral density; LIHC trans rs783540 0.934 rs10400906 chr15:83297138 A/G cg18393722 chr15:85113863 UBE2QP1 0.36 6.27 0.32 1.1e-9 Schizophrenia; LIHC cis rs12586317 0.547 rs10134907 chr14:35499211 A/C cg16230307 chr14:35515116 FAM177A1 0.78 13.24 0.58 1.39e-32 Psoriasis; LIHC cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg18867708 chr6:26865862 GUSBL1 -0.5 -7.69 -0.38 1.59e-13 Schizophrenia; LIHC cis rs2997447 0.761 rs17257113 chr1:26449595 G/A cg19633962 chr1:26362018 EXTL1 -0.65 -5.96 -0.31 6.31e-9 QRS complex (12-leadsum); LIHC cis rs7584330 0.826 rs72620824 chr2:238381083 G/A cg14458575 chr2:238380390 NA 0.52 7.64 0.38 2.21e-13 Prostate cancer; LIHC cis rs9914988 0.943 rs4794839 chr17:27131393 G/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.82 -0.35 4.05e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7918232 0.782 rs7910168 chr10:27465296 G/A cg14442939 chr10:27389572 ANKRD26 0.72 7.07 0.36 8.65e-12 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05318427 chr2:85199320 KCMF1 0.42 6.74 0.34 6.71e-11 Cognitive function; LIHC trans rs8073060 0.586 rs226087 chr17:34017652 T/C cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs708547 0.647 rs781668 chr4:57825140 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.47 -7.02 -0.35 1.21e-11 Response to bleomycin (chromatid breaks); LIHC cis rs734999 0.545 rs28568531 chr1:2555640 T/A cg18854424 chr1:2615690 NA 0.34 7.39 0.37 1.12e-12 Ulcerative colitis; LIHC cis rs7027203 0.828 rs3957506 chr9:96588133 C/T cg13679303 chr9:96623674 NA -0.29 -6.51 -0.33 2.72e-10 DNA methylation (variation); LIHC trans rs2243480 1.000 rs2460422 chr7:65601505 C/T cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs5758511 0.689 rs62240864 chr22:42563889 C/T cg00645731 chr22:42541494 CYP2D7P1 0.71 6.53 0.33 2.31e-10 Birth weight; LIHC cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg20090690 chr10:134436459 INPP5A 0.44 5.89 0.3 9.21e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg07061783 chr6:25882402 NA -0.49 -6.86 -0.35 3.21e-11 Blood metabolite levels; LIHC cis rs40363 0.645 rs250631 chr16:3523215 G/C cg05754148 chr16:3507555 NAT15 0.38 5.87 0.3 1.02e-8 Tuberculosis; LIHC cis rs6933660 0.800 rs13201167 chr6:151773504 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.63 10.14 0.48 2.61e-21 Menarche (age at onset); LIHC cis rs796364 0.806 rs10445791 chr2:201078307 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.64 -6.74 -0.34 6.95e-11 Schizophrenia; LIHC cis rs8014671 0.519 rs12884918 chr14:70890778 T/C cg25576086 chr14:70833871 SYNJ2BP -0.46 -7.14 -0.36 5.58e-12 Prostate cancer; LIHC cis rs1538970 0.816 rs11211123 chr1:45957609 G/A cg05343316 chr1:45956843 TESK2 0.63 9.45 0.46 5.47e-19 Platelet count; LIHC cis rs2842992 0.750 rs2758354 chr6:160125854 A/G cg26839252 chr6:160211577 TCP1;MRPL18 0.35 5.96 0.31 6.21e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs2760061 0.624 rs10442629 chr1:228191070 T/A cg02753203 chr1:228287806 NA 0.68 9.68 0.46 9.56e-20 Diastolic blood pressure; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.51 -7.21 -0.36 3.72e-12 Height; LIHC cis rs8060686 0.565 rs36046686 chr16:68122269 T/C cg05110241 chr16:68378359 PRMT7 -0.6 -7.01 -0.35 1.32e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.75 0.47 5.42e-20 Mean platelet volume; LIHC cis rs67478160 0.643 rs2024667 chr14:104211529 T/G cg01849466 chr14:104193079 ZFYVE21 -0.44 -7.07 -0.36 8.53e-12 Schizophrenia; LIHC cis rs710216 0.843 rs710220 chr1:43415346 G/T cg03128534 chr1:43423976 SLC2A1 0.45 6.1 0.31 2.93e-9 Red cell distribution width; LIHC cis rs12048904 0.541 rs6699536 chr1:101276544 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.57 9.52 0.46 3.13e-19 Multiple sclerosis; LIHC cis rs11190604 1.000 rs10883496 chr10:102221931 T/C cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.2e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.95 8.47 0.42 7.2e-16 Platelet count; LIHC cis rs10883723 0.810 rs10748823 chr10:104274465 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.94 0.57 1.83e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg10295955 chr4:187884368 NA 1.0 23.47 0.79 2.95e-73 Lobe attachment (rater-scored or self-reported); LIHC cis rs7712401 0.791 rs10071135 chr5:122146978 C/G cg18764291 chr5:122110994 SNX2 0.35 6.18 0.32 1.86e-9 Mean platelet volume; LIHC cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg00091569 chr3:40428383 ENTPD3 0.38 6.58 0.34 1.82e-10 Renal cell carcinoma; LIHC cis rs651907 0.557 rs3094297 chr3:101399260 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.45 -6.51 -0.33 2.75e-10 Colorectal cancer; LIHC cis rs7208859 0.673 rs36056619 chr17:29172284 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg08219700 chr8:58056026 NA 0.52 7.02 0.35 1.21e-11 Developmental language disorder (linguistic errors); LIHC cis rs8072100 0.967 rs2317826 chr17:45730899 C/T cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.36 -5.82 -0.3 1.37e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs600806 0.888 rs10745352 chr1:109871787 T/C cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.91 -0.3 8.28e-9 Intelligence (multi-trait analysis); LIHC cis rs6088590 1.000 rs6120705 chr20:33313740 T/C cg24642439 chr20:33292090 TP53INP2 0.81 11.77 0.54 4.55e-27 Coronary artery disease; LIHC trans rs5756813 0.661 rs2285178 chr22:38205989 T/C cg19894588 chr14:64061835 NA -0.69 -10.19 -0.48 1.76e-21 Optic cup area;Vertical cup-disc ratio; LIHC trans rs3780486 0.846 rs7864705 chr9:33140352 A/C cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs9457247 1.000 rs364451 chr6:167384756 G/A cg07741184 chr6:167504864 NA 0.29 6.82 0.35 4.23e-11 Crohn's disease; LIHC cis rs10056811 0.538 rs56174528 chr5:74400516 G/C cg19683494 chr5:74908142 NA 0.7 7.7 0.38 1.5e-13 Coronary artery disease; LIHC cis rs2710247 1 rs2710247 chr2:219467508 A/G cg02985541 chr2:219472218 PLCD4 0.44 8.33 0.41 2.04e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg05484376 chr2:27715224 FNDC4 0.36 6.16 0.32 2.07e-9 Total body bone mineral density; LIHC cis rs17125944 0.505 rs75661138 chr14:53259262 G/A cg13660082 chr14:53194042 PSMC6 -0.46 -7.44 -0.37 8.37e-13 Alzheimer's disease (late onset); LIHC cis rs1401999 0.898 rs6443928 chr3:183729487 C/T cg20387954 chr3:183756860 HTR3D 0.28 5.98 0.31 5.57e-9 Anterior chamber depth; LIHC cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg12463550 chr7:65579703 CRCP 0.71 7.45 0.37 7.63e-13 Diabetic kidney disease; LIHC cis rs6570726 0.791 rs7765675 chr6:145915077 A/C cg13319975 chr6:146136371 FBXO30 -0.42 -6.52 -0.33 2.53e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2292096 0.929 rs6667419 chr1:200756197 G/A cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.21 -0.32 1.52e-9 Epilepsy; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg13409248 chr3:40428643 ENTPD3 0.47 7.81 0.39 6.89e-14 Renal cell carcinoma; LIHC cis rs2991971 0.933 rs666720 chr1:46020795 T/C cg15605315 chr1:45957053 TESK2 0.45 5.79 0.3 1.63e-8 High light scatter reticulocyte count; LIHC cis rs2108622 0.727 rs3093207 chr19:15988658 T/C cg13772218 chr19:15982569 NA 0.36 7.35 0.37 1.49e-12 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs8062405 0.755 rs4788073 chr16:28594549 A/G cg07382826 chr16:28625726 SULT1A1 0.49 7.72 0.39 1.26e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10463316 0.608 rs13360453 chr5:150769143 T/C cg03212797 chr5:150827313 SLC36A1 -0.44 -6.73 -0.34 7.3e-11 Metabolite levels (Pyroglutamine); LIHC cis rs66573146 0.634 rs55633489 chr4:6988745 C/A cg15105060 chr4:7024189 TBC1D14 -0.81 -6.83 -0.35 3.85e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs7707921 1.000 rs891159 chr5:81491087 A/G cg15871215 chr5:81402204 ATG10 -0.61 -6.14 -0.31 2.32e-9 Breast cancer; LIHC cis rs4319547 1.000 rs9705654 chr12:123083508 T/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.12 -0.36 6.26e-12 Body mass index; LIHC cis rs1506636 1.000 rs2259457 chr7:123424350 A/G cg03229431 chr7:123269106 ASB15 0.6 11.91 0.54 1.36e-27 Plateletcrit;Platelet count; LIHC cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg26752003 chr8:145688521 CYHR1 0.61 9.71 0.46 7.77e-20 Age at first birth; LIHC cis rs12744310 0.887 rs12757611 chr1:41808972 C/T cg03962019 chr1:41807865 NA 0.36 5.79 0.3 1.62e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7918232 0.825 rs4749233 chr10:27467967 G/A cg14442939 chr10:27389572 ANKRD26 0.72 7.07 0.36 8.65e-12 Breast cancer; LIHC cis rs11098699 0.821 rs11098705 chr4:124229644 C/T cg09941581 chr4:124220074 SPATA5 0.32 6.45 0.33 3.82e-10 Mosquito bite size; LIHC cis rs12701220 0.522 rs12701455 chr7:1055409 A/G cg04025307 chr7:1156635 C7orf50 0.47 6.7 0.34 8.67e-11 Bronchopulmonary dysplasia; LIHC cis rs7903847 0.642 rs7092499 chr10:99140313 A/G cg20016023 chr10:99160130 RRP12 -0.41 -6.43 -0.33 4.32e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11674184 0.632 rs17529680 chr2:11727087 A/C cg07314298 chr2:11723111 GREB1 0.51 8.23 0.41 4.09e-15 Endometriosis; LIHC cis rs916888 0.773 rs199457 chr17:44795469 C/T cg15921436 chr17:44337874 NA 0.65 6.6 0.34 1.54e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7208859 0.623 rs11651858 chr17:29170718 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1865760 0.516 rs9393683 chr6:26066198 A/G cg17691542 chr6:26056736 HIST1H1C 0.45 6.44 0.33 3.97e-10 Height; LIHC cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg22800045 chr5:56110881 MAP3K1 0.56 7.06 0.36 9.42e-12 Initial pursuit acceleration; LIHC cis rs4474465 0.646 rs7937417 chr11:78284470 A/G cg02023728 chr11:77925099 USP35 -0.34 -6.06 -0.31 3.56e-9 Alzheimer's disease (survival time); LIHC cis rs11758351 1.000 rs76722536 chr6:26192946 C/G cg16070018 chr6:26224392 HIST1H3E 0.58 6.99 0.35 1.41e-11 Gout;Renal underexcretion gout; LIHC cis rs709400 0.628 rs1989565 chr14:103862193 G/A cg26031613 chr14:104095156 KLC1 -0.73 -9.21 -0.45 3.24e-18 Body mass index; LIHC cis rs4919087 0.715 rs946981 chr10:98995076 A/G cg25902810 chr10:99078978 FRAT1 -0.51 -5.81 -0.3 1.45e-8 Monocyte count; LIHC cis rs2576037 0.583 rs487386 chr18:44377004 A/G cg19077165 chr18:44547161 KATNAL2 -0.44 -6.56 -0.33 2.05e-10 Personality dimensions; LIHC cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg23205692 chr1:25664452 TMEM50A 0.39 6.34 0.32 7.44e-10 Erythrocyte sedimentation rate; LIHC cis rs875971 0.964 rs12668936 chr7:65914404 C/T cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs8062405 0.755 rs7186573 chr16:28587389 T/C cg16576597 chr16:28551801 NUPR1 0.47 7.33 0.37 1.67e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg17747265 chr1:1875780 NA -0.58 -11.31 -0.52 2.11e-25 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02602480 chr2:62422689 B3GNT2 0.45 7.17 0.36 4.6e-12 Pancreatic cancer; LIHC cis rs1707322 0.752 rs12027622 chr1:46130252 A/C cg06784218 chr1:46089804 CCDC17 0.41 7.49 0.38 5.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9910055 0.552 rs4793084 chr17:42317371 G/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.37 -6.65 -0.34 1.13e-10 Total body bone mineral density; LIHC cis rs6952808 0.531 rs73039217 chr7:2178731 G/A cg04267008 chr7:1944627 MAD1L1 -0.49 -7.49 -0.38 5.83e-13 Bipolar disorder and schizophrenia; LIHC cis rs644799 0.896 rs4430471 chr11:95646774 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 15.67 0.65 4.38e-42 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9467773 0.869 rs742090 chr6:26415637 A/C cg09904177 chr6:26538194 HMGN4 -0.49 -8.89 -0.43 3.46e-17 Intelligence (multi-trait analysis); LIHC cis rs6121246 0.567 rs6088796 chr20:30213229 C/T cg13852791 chr20:30311386 BCL2L1 0.78 6.77 0.34 5.69e-11 Mean corpuscular hemoglobin; LIHC cis rs4843747 0.671 rs13334603 chr16:88116016 T/C cg00677901 chr16:88017247 BANP 0.52 8.1 0.4 9.58e-15 Menopause (age at onset); LIHC cis rs701145 0.617 rs9820619 chr3:154028294 G/T cg16511985 chr3:153974050 SGEF 0.41 8.45 0.42 8.74e-16 Coronary artery disease; LIHC cis rs8177179 0.967 rs6439434 chr3:133450371 T/G cg16262614 chr3:133464971 TF 0.46 10.36 0.49 4.53e-22 Iron status biomarkers (transferrin levels); LIHC cis rs986417 0.818 rs6573319 chr14:61091913 C/G cg27398547 chr14:60952738 C14orf39 0.59 6.19 0.32 1.71e-9 Gut microbiota (bacterial taxa); LIHC cis rs637571 0.676 rs634534 chr11:65665256 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.4 -5.74 -0.3 2.08e-8 Eosinophil percentage of white cells; LIHC cis rs6598955 0.756 rs10902723 chr1:26568542 T/C cg04990556 chr1:26633338 UBXN11 -0.61 -10.12 -0.48 3.16e-21 Obesity-related traits; LIHC cis rs2019216 0.521 rs6565386 chr17:21901755 A/G cg22648282 chr17:21454238 C17orf51 0.39 6.32 0.32 8e-10 Pelvic organ prolapse; LIHC trans rs35995292 0.963 rs7803397 chr7:38905686 C/T cg06118584 chr16:11770950 SNN 0.32 6.05 0.31 3.86e-9 Subjective well-being (multi-trait analysis); LIHC cis rs11229555 0.645 rs11229436 chr11:58186009 G/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg00800038 chr16:89945340 TCF25 -0.69 -10.43 -0.49 2.64e-22 Skin colour saturation; LIHC cis rs1003719 0.788 rs4817843 chr21:38447040 C/A cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg23978390 chr7:1156363 C7orf50 0.48 7.4 0.37 1.05e-12 Longevity;Endometriosis; LIHC cis rs7193541 0.662 rs8058133 chr16:74657485 A/T cg01733217 chr16:74700730 RFWD3 0.92 21.4 0.76 4.51e-65 Multiple myeloma; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg11766577 chr21:47581405 C21orf56 0.43 7.15 0.36 5.39e-12 Testicular germ cell tumor; LIHC cis rs6964587 0.900 rs6972027 chr7:91781380 T/C cg17063962 chr7:91808500 NA 1.05 22.28 0.77 1.42e-68 Breast cancer; LIHC cis rs7264396 0.513 rs2425092 chr20:34306815 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg18357526 chr6:26021779 HIST1H4A 1.06 15.81 0.65 1.17e-42 Intelligence (multi-trait analysis); LIHC cis rs798554 0.704 rs798531 chr7:2770067 G/C cg13628971 chr7:2884303 GNA12 0.4 6.32 0.32 8.35e-10 Height; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg11905131 chr22:24372483 LOC391322 -0.71 -10.7 -0.5 3.17e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs72634258 0.945 rs2050198 chr1:8111839 T/G cg00042356 chr1:8021962 PARK7 0.85 8.33 0.41 1.95e-15 Inflammatory bowel disease; LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg08219700 chr8:58056026 NA 0.5 6.81 0.35 4.4e-11 Developmental language disorder (linguistic errors); LIHC cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg27170947 chr2:26402098 FAM59B -0.68 -8.4 -0.41 1.25e-15 Gut microbiome composition (summer); LIHC cis rs12980942 0.935 rs11880564 chr19:41831196 C/A cg25627403 chr19:41769009 HNRNPUL1 0.56 6.81 0.35 4.29e-11 Coronary artery disease; LIHC cis rs1348850 0.874 rs4893822 chr2:178285727 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 13.71 0.6 2.06e-34 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg09222892 chr1:25734099 RHCE 0.48 8.89 0.43 3.55e-17 Erythrocyte sedimentation rate; LIHC cis rs10876993 0.821 rs1629032 chr12:58038686 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.39 -0.33 5.51e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs9549328 0.800 rs9549616 chr13:113627762 T/G cg04958157 chr13:113748321 MCF2L -0.35 -5.72 -0.3 2.37e-8 Systolic blood pressure; LIHC cis rs12928939 0.862 rs7197104 chr16:71794061 C/T cg03805757 chr16:71968109 PKD1L3 -0.73 -8.73 -0.43 1.11e-16 Post bronchodilator FEV1; LIHC cis rs2336384 1.000 rs873457 chr1:12046334 C/G cg13216073 chr1:12042593 MFN2 0.38 5.72 0.3 2.3e-8 Platelet count; LIHC cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg16262614 chr3:133464971 TF 0.29 6.49 0.33 3.1e-10 Iron status biomarkers; LIHC cis rs116248771 0.549 rs9825140 chr3:158435374 C/T cg16708174 chr3:158430962 RARRES1 0.76 9.78 0.47 4.54e-20 diarrhoeal disease at age 2; LIHC cis rs6754311 0.593 rs10186843 chr2:136586958 C/A cg25344623 chr2:136566232 LCT 0.41 8.33 0.41 1.99e-15 Mosquito bite size; LIHC cis rs11229555 0.609 rs12270515 chr11:58217945 G/A cg15696309 chr11:58395628 NA -0.65 -7.5 -0.38 5.44e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs7937682 0.575 rs7950926 chr11:111776437 G/C cg18187862 chr3:45730750 SACM1L -0.51 -6.37 -0.33 6.26e-10 Primary sclerosing cholangitis; LIHC cis rs6665290 0.904 rs7541033 chr1:227188371 C/A cg10327440 chr1:227177885 CDC42BPA -1.18 -26.55 -0.82 4.16e-85 Myeloid white cell count; LIHC cis rs1568889 0.838 rs11030229 chr11:28173634 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.27 0.61 1.4e-36 Bipolar disorder; LIHC cis rs9303401 0.661 rs9902820 chr17:56637545 A/C cg25039879 chr17:56429692 SUPT4H1 0.43 6.03 0.31 4.37e-9 Cognitive test performance; LIHC cis rs9457247 0.765 rs2237276 chr6:167442115 C/T cg23791538 chr6:167370224 RNASET2 -0.51 -7.84 -0.39 5.82e-14 Crohn's disease; LIHC cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg00166722 chr3:10149974 C3orf24 0.47 5.82 0.3 1.36e-8 Alzheimer's disease; LIHC cis rs644799 1.000 rs7749 chr11:95565789 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.59 0.46 1.87e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs77741769 0.529 rs7137504 chr12:121221628 C/T cg02419362 chr12:121203948 SPPL3 0.33 5.72 0.3 2.37e-8 Mean corpuscular volume; LIHC cis rs9457247 1.000 rs415890 chr6:167406633 C/G cg23791538 chr6:167370224 RNASET2 0.65 11.09 0.51 1.25e-24 Crohn's disease; LIHC cis rs11588062 0.601 rs11579255 chr1:46806959 C/T cg15696662 chr1:46669221 C1orf190;POMGNT1 0.43 6.69 0.34 9.12e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs240764 0.555 rs4840150 chr6:101183774 T/C cg12253828 chr6:101329408 ASCC3 0.43 6.81 0.35 4.5e-11 Neuroticism; LIHC cis rs344364 0.511 rs2982447 chr16:1947413 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 0.57 7.55 0.38 4.1e-13 Glomerular filtration rate in chronic kidney disease; LIHC cis rs1185460 0.565 rs1182922 chr11:118932859 G/A cg01677386 chr11:118938358 VPS11 0.44 5.85 0.3 1.17e-8 Coronary artery disease; LIHC cis rs12079745 0.793 rs75134881 chr1:169186127 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.65 -6.13 -0.31 2.39e-9 QT interval; LIHC cis rs950776 0.518 rs12900783 chr15:78815523 G/A cg06917634 chr15:78832804 PSMA4 0.93 14.06 0.61 9.61e-36 Sudden cardiac arrest; LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg07167872 chr1:205819463 PM20D1 0.71 10.51 0.49 1.38e-22 Menarche (age at onset); LIHC cis rs425277 0.959 rs77665022 chr1:2065958 C/T cg24578937 chr1:2090814 PRKCZ 0.48 8.36 0.41 1.56e-15 Height; LIHC cis rs826838 1.000 rs10880963 chr12:38748408 T/C cg26384229 chr12:38710491 ALG10B 1.04 13.79 0.6 1.09e-34 Heart rate; LIHC cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg19318889 chr4:1322082 MAEA 0.39 6.35 0.32 6.73e-10 Obesity-related traits; LIHC cis rs2439831 1.000 rs689826 chr15:43749916 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.76 12.95 0.57 1.72e-31 Lung cancer in ever smokers; LIHC cis rs12995491 0.698 rs34352413 chr2:88498754 T/G cg04511125 chr2:88470314 THNSL2 -0.47 -6.94 -0.35 2.03e-11 Response to metformin (IC50); LIHC cis rs2153535 0.601 rs9393030 chr6:8516489 C/G cg23788917 chr6:8435910 SLC35B3 0.6 8.63 0.42 2.3e-16 Motion sickness; LIHC cis rs7044106 0.887 rs1359328 chr9:123370822 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.63 8.97 0.44 2.02e-17 Hip circumference adjusted for BMI; LIHC cis rs7635838 0.859 rs6784883 chr3:11444453 G/A cg00170343 chr3:11313890 ATG7 0.42 6.47 0.33 3.34e-10 HDL cholesterol; LIHC cis rs61990749 0.597 rs176946 chr14:78178439 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.28 0.49 8.68e-22 Fibroblast growth factor basic levels; LIHC cis rs11105298 0.891 rs10858890 chr12:89907166 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.59 -0.38 2.98e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7575217 0.682 rs4851401 chr2:101700518 T/C cg23907051 chr2:101730305 TBC1D8 0.25 5.78 0.3 1.66e-8 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; LIHC cis rs10870270 1.000 rs10159943 chr10:133744744 T/C cg26149184 chr10:133730230 NA 0.47 7.36 0.37 1.36e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs778371 0.723 rs6739794 chr2:233576165 G/A cg08000102 chr2:233561755 GIGYF2 0.87 14.54 0.62 1.3e-37 Schizophrenia; LIHC cis rs12744310 1.000 rs12032514 chr1:41760562 G/A cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.72e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg06238570 chr21:40685208 BRWD1 -0.54 -8.87 -0.43 4.12e-17 Cognitive function; LIHC cis rs11146838 1 rs11146838 chr10:39149977 A/T cg25951256 chr10:38645740 HSD17B7P2 -0.41 -6.03 -0.31 4.32e-9 Breast cancer; LIHC cis rs11758351 1.000 rs78012445 chr6:26195080 G/C cg16070018 chr6:26224392 HIST1H3E 0.57 6.81 0.35 4.47e-11 Gout;Renal underexcretion gout; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18876457 chr1:160071037 NA 0.44 6.6 0.34 1.59e-10 Pancreatic cancer; LIHC cis rs10097731 0.901 rs4398860 chr8:82041753 C/T cg25230327 chr8:82042993 NA -0.6 -7.73 -0.39 1.24e-13 Serum total protein level; LIHC cis rs151997 0.537 rs11746939 chr5:50268856 G/A cg06027927 chr5:50259733 NA 0.52 6.36 0.33 6.5e-10 Callous-unemotional behaviour; LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg12419862 chr22:24373484 LOC391322 0.76 11.85 0.54 2.22e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6088580 0.634 rs6059824 chr20:33014543 T/C cg08999081 chr20:33150536 PIGU 0.67 13.35 0.59 5.28e-33 Glomerular filtration rate (creatinine); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg02873885 chr7:55000889 NA 0.4 7.52 0.38 4.92e-13 Calcium levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg18240814 chr5:107718300 FBXL17 -0.38 -6.04 -0.31 3.92e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs911119 0.908 rs8121147 chr20:23601708 T/C cg16589663 chr20:23618590 CST3 0.74 7.78 0.39 8.48e-14 Chronic kidney disease; LIHC cis rs4147929 1.000 rs4147929 chr19:1063443 A/G cg05372495 chr19:1063624 ABCA7 -0.44 -6.21 -0.32 1.57e-9 Alzheimer's disease (late onset); LIHC cis rs6542838 0.641 rs6724477 chr2:99537074 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.37 5.87 0.3 1.03e-8 Fear of minor pain; LIHC cis rs8005677 1.000 rs8014936 chr14:23375145 A/G cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 3.07e-9 Cognitive ability (multi-trait analysis); LIHC cis rs7520050 0.898 rs34175029 chr1:46483871 C/T cg03146154 chr1:46216737 IPP -0.39 -6.38 -0.33 5.77e-10 Red blood cell count;Reticulocyte count; LIHC cis rs16828019 0.777 rs11209363 chr1:41485077 T/C cg03387723 chr1:41708464 SCMH1 -0.42 -6.7 -0.34 8.55e-11 Intelligence (multi-trait analysis); LIHC cis rs4908768 0.906 rs7539382 chr1:8579301 C/T cg25722041 chr1:8623473 RERE 0.41 5.84 0.3 1.23e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs2019216 0.538 rs2341278 chr17:21994959 G/A cg14296220 chr9:32431791 ACO1 0.39 6.32 0.32 8.24e-10 Pelvic organ prolapse; LIHC cis rs986417 0.818 rs10148116 chr14:61101089 C/T cg27398547 chr14:60952738 C14orf39 0.66 7.32 0.37 1.81e-12 Gut microbiota (bacterial taxa); LIHC cis rs10461617 0.617 rs1423623 chr5:56065575 A/G cg12311346 chr5:56204834 C5orf35 0.53 7.55 0.38 3.98e-13 Type 2 diabetes; LIHC cis rs6088813 1.000 rs6088823 chr20:33994265 G/T cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg06420487 chr17:61919686 SMARCD2 0.46 6.26 0.32 1.16e-9 Height; LIHC cis rs2455601 0.507 rs7948452 chr11:8877704 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.5 -8.6 -0.42 2.91e-16 Schizophrenia; LIHC cis rs9649465 1.000 rs2299982 chr7:123356511 A/C cg03229431 chr7:123269106 ASB15 -0.37 -7.96 -0.4 2.58e-14 Migraine; LIHC cis rs9790314 0.645 rs9879687 chr3:160874938 A/G cg03342759 chr3:160939853 NMD3 -0.8 -13.27 -0.58 1.09e-32 Morning vs. evening chronotype; LIHC cis rs2832191 0.791 rs7282843 chr21:30475226 A/G cg08807101 chr21:30365312 RNF160 0.63 10.02 0.48 6.71e-21 Dental caries; LIHC cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 7.33 0.37 1.63e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs9303401 0.659 rs2072316 chr17:56604813 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.94 12.78 0.57 7.62e-31 Cognitive test performance; LIHC cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg06238570 chr21:40685208 BRWD1 -0.39 -6.26 -0.32 1.18e-9 Menarche (age at onset); LIHC cis rs4819052 0.851 rs7279011 chr21:46655995 G/A cg22633049 chr21:46681294 NA -0.36 -5.96 -0.31 6.15e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7100689 0.577 rs2236569 chr10:82043576 G/A cg01528321 chr10:82214614 TSPAN14 0.85 11.68 0.53 9.44e-27 Post bronchodilator FEV1; LIHC cis rs7212590 0.748 rs9904374 chr17:57908096 T/C cg10252138 chr17:58120427 NA -0.58 -5.72 -0.3 2.33e-8 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs7618501 0.633 rs12496973 chr3:50002245 T/C cg24110177 chr3:50126178 RBM5 -0.46 -7.53 -0.38 4.48e-13 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg00106254 chr7:1943704 MAD1L1 -0.44 -7.22 -0.36 3.46e-12 Bipolar disorder and schizophrenia; LIHC cis rs2230307 0.536 rs7530361 chr1:100462860 T/C cg24955406 chr1:100503596 HIAT1 0.61 6.12 0.31 2.55e-9 Carotid intima media thickness; LIHC cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC trans rs4820294 0.669 rs9622678 chr22:38057338 A/G cg19894588 chr14:64061835 NA -0.46 -7.35 -0.37 1.52e-12 Fat distribution (HIV); LIHC cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg24531977 chr5:56204891 C5orf35 -0.65 -9.43 -0.45 6.5e-19 Initial pursuit acceleration; LIHC cis rs7918232 1.000 rs6482595 chr10:27380261 A/G cg14442939 chr10:27389572 ANKRD26 -0.57 -6.42 -0.33 4.68e-10 Breast cancer; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg25631650 chr19:633157 POLRMT -0.49 -6.06 -0.31 3.5e-9 Facial morphology (factor 20); LIHC cis rs2836974 0.583 rs9636957 chr21:40705847 G/A cg11890956 chr21:40555474 PSMG1 -0.47 -7.53 -0.38 4.51e-13 Cognitive function; LIHC cis rs61990749 0.597 rs2267759 chr14:78147615 C/T cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.71 0.38 1.35e-13 Fibroblast growth factor basic levels; LIHC cis rs10411936 0.608 rs7259642 chr19:16601926 C/A cg10248733 chr19:16607483 C19orf44;CALR3 0.49 6.56 0.33 1.98e-10 White blood cell count;Multiple sclerosis; LIHC cis rs9611565 0.559 rs5758412 chr22:42080803 T/A cg03806693 chr22:41940476 POLR3H 0.98 10.61 0.5 6.31e-23 Vitiligo; LIHC cis rs2115630 0.967 rs12595786 chr15:85336670 T/C cg12501888 chr15:85177176 SCAND2 -0.48 -7.37 -0.37 1.31e-12 P wave terminal force; LIHC cis rs7945705 0.783 rs11042125 chr11:8938049 A/T cg21881798 chr11:8931708 C11orf17;ST5 -0.37 -6.29 -0.32 9.94e-10 Hemoglobin concentration; LIHC cis rs3106136 0.527 rs10016806 chr4:95158495 G/T cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.06 -0.44 1.01e-17 Capecitabine sensitivity; LIHC cis rs1008375 1.000 rs10805357 chr4:17652352 G/A cg02297831 chr4:17616191 MED28 0.49 7.76 0.39 9.95e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6089584 0.888 rs6061973 chr20:60610870 C/T cg23262073 chr20:60523788 NA -0.28 -5.85 -0.3 1.13e-8 Body mass index; LIHC cis rs3762637 0.943 rs6762156 chr3:122236025 A/C cg24169773 chr3:122142474 KPNA1 -0.44 -8.84 -0.43 5.15e-17 LDL cholesterol levels; LIHC cis rs11711311 0.824 rs35952547 chr3:113352501 G/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.35 6.02 0.31 4.45e-9 IgG glycosylation; LIHC cis rs12950390 0.853 rs11658511 chr17:45856918 T/C cg03474202 chr17:45855739 NA -0.35 -5.99 -0.31 5.39e-9 IgG glycosylation; LIHC cis rs2404602 0.692 rs60658665 chr15:77042508 T/C cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.9e-38 Blood metabolite levels; LIHC cis rs9302635 0.513 rs8050238 chr16:72154187 C/T cg01557791 chr16:72042693 DHODH -0.47 -7.13 -0.36 5.94e-12 Blood protein levels; LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg02290350 chr8:58132656 NA 0.48 9.89 0.47 1.84e-20 Developmental language disorder (linguistic errors); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg15069758 chr1:110198731 GSTM4 0.43 6.25 0.32 1.19e-9 Migraine with aura; LIHC cis rs2933343 0.621 rs883843 chr3:128567383 C/T cg25356066 chr3:128598488 ACAD9 -0.52 -7.07 -0.36 8.59e-12 IgG glycosylation; LIHC cis rs12477438 0.520 rs11123762 chr2:99727789 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.68 0.78 3.75e-70 Chronic sinus infection; LIHC cis rs2295359 0.892 rs2064689 chr1:67653010 G/A cg12940439 chr1:67600707 NA 0.35 6.15 0.32 2.18e-9 Psoriasis; LIHC cis rs13256369 1.000 rs13266699 chr8:8570313 A/T cg17143192 chr8:8559678 CLDN23 -0.72 -11.51 -0.53 4.08e-26 Obesity-related traits; LIHC cis rs2404602 0.552 rs4886823 chr15:76965402 A/G cg03037974 chr15:76606532 NA -0.51 -8.19 -0.41 5.17e-15 Blood metabolite levels; LIHC trans rs2243480 1.000 rs1618893 chr7:66096119 C/T cg10756647 chr7:56101905 PSPH 0.88 11.06 0.51 1.69e-24 Diabetic kidney disease; LIHC cis rs3770081 1.000 rs1036554 chr2:86236099 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -9.05 -0.44 1.09e-17 Facial emotion recognition (sad faces); LIHC trans rs7618501 1.000 rs7649348 chr3:49772375 G/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg26338869 chr17:61819248 STRADA 0.53 7.13 0.36 5.96e-12 Height; LIHC cis rs1008375 0.900 rs4698625 chr4:17599500 G/T cg16339924 chr4:17578868 LAP3 0.53 7.14 0.36 5.79e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg06138931 chr13:21896616 NA 0.57 9.91 0.47 1.65e-20 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs1814175 0.645 rs1851853 chr11:49953434 C/T cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs5753618 0.539 rs4820962 chr22:31689951 A/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.81 -0.39 7.1e-14 Colorectal cancer; LIHC cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg23248424 chr5:179741104 GFPT2 -0.42 -6.38 -0.33 5.71e-10 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21144462 chr17:42082647 PYY;NAGS 0.46 6.64 0.34 1.23e-10 Lung function (FEV1/FVC); LIHC cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.51e-29 Menopause (age at onset); LIHC cis rs9640161 0.830 rs3757425 chr7:150067640 A/C cg21361702 chr7:150065534 REPIN1 0.51 7.28 0.37 2.33e-12 Blood protein levels;Circulating chemerin levels; LIHC trans rs2073499 0.935 rs2236939 chr3:50243510 G/T cg21659725 chr3:3221576 CRBN 0.62 7.0 0.35 1.38e-11 Schizophrenia; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg01516881 chr6:292596 DUSP22 -0.57 -7.68 -0.38 1.67e-13 Menopause (age at onset); LIHC cis rs4843747 0.749 rs13333619 chr16:88072076 C/T cg00677901 chr16:88017247 BANP 0.63 9.54 0.46 2.89e-19 Menopause (age at onset); LIHC cis rs9457247 0.765 rs10455982 chr6:167448728 C/T cg12798992 chr6:167411361 FGFR1OP 0.48 7.2 0.36 3.84e-12 Crohn's disease; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg11060661 chr22:24314208 DDT;DDTL 0.62 10.44 0.49 2.47e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7089973 0.604 rs3758603 chr10:116605368 T/C cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1982963 0.951 rs2516592 chr14:52503545 A/G cg10843707 chr14:52510701 NID2 -0.46 -7.59 -0.38 3.13e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg08219700 chr8:58056026 NA 0.52 6.22 0.32 1.43e-9 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.659 rs56162835 chr17:56687315 A/G cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs459571 0.959 rs465535 chr9:136910905 C/T cg13789015 chr9:136890014 NCRNA00094 0.43 7.87 0.39 4.6e-14 Platelet distribution width; LIHC cis rs507080 0.922 rs516153 chr11:118564762 C/A cg04173919 chr11:118528438 PHLDB1 0.36 6.6 0.34 1.53e-10 Serum metabolite levels; LIHC cis rs7107174 0.748 rs11237458 chr11:78050849 A/T cg02023728 chr11:77925099 USP35 0.43 8.33 0.41 1.98e-15 Testicular germ cell tumor; LIHC cis rs17152411 0.895 rs7086128 chr10:126587373 A/G cg07906193 chr10:126599966 NA 0.39 6.52 0.33 2.49e-10 Height; LIHC cis rs370915 0.890 rs28610515 chr4:187835260 A/T cg19519643 chr4:187840862 NA -0.54 -9.33 -0.45 1.4e-18 Gout; LIHC cis rs11098499 0.754 rs938056 chr4:120237453 C/T cg09307838 chr4:120376055 NA 0.7 10.96 0.51 3.8e-24 Corneal astigmatism; LIHC cis rs9896052 0.580 rs8065142 chr17:73441060 G/A cg25649188 chr17:73499917 CASKIN2 0.43 6.81 0.35 4.32e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs10751667 0.857 rs6597961 chr11:976677 T/C cg10932868 chr11:921992 NA 0.36 6.77 0.34 5.46e-11 Alzheimer's disease (late onset); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg12820191 chr3:186524311 RFC4 -0.52 -7.35 -0.37 1.45e-12 Systolic blood pressure; LIHC cis rs7408868 0.764 rs12610803 chr19:15260682 A/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.76 -0.3 1.84e-8 Pulse pressure; LIHC trans rs11098499 0.863 rs7699064 chr4:120428309 A/G cg25214090 chr10:38739885 LOC399744 -0.58 -8.95 -0.44 2.39e-17 Corneal astigmatism; LIHC cis rs36051895 0.632 rs12684720 chr9:5150800 T/C cg02405213 chr9:5042618 JAK2 -0.68 -12.25 -0.55 7.47e-29 Pediatric autoimmune diseases; LIHC cis rs3099143 1.000 rs3099142 chr15:77104909 C/T cg21673338 chr15:77095150 SCAPER -0.51 -7.64 -0.38 2.21e-13 Recalcitrant atopic dermatitis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11102324 chr15:49658865 C15orf33 0.41 6.21 0.32 1.54e-9 Longevity; LIHC cis rs2439831 0.850 rs9944216 chr15:44160773 C/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.6 -7.21 -0.36 3.7e-12 Lung cancer in ever smokers; LIHC cis rs796364 1.000 rs1509835 chr2:200814809 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.1 0.44 7.62e-18 Schizophrenia; LIHC cis rs2439831 0.614 rs2467733 chr15:43693328 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.93 0.51 4.89e-24 Lung cancer in ever smokers; LIHC cis rs9517320 0.534 rs3858778 chr13:99172249 A/C cg07423050 chr13:99094983 FARP1 0.49 8.31 0.41 2.28e-15 Longevity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03217964 chr16:75182191 ZFP1 0.45 6.63 0.34 1.29e-10 Pancreatic cancer; LIHC cis rs2153535 0.546 rs9378559 chr6:8539058 A/T cg07606381 chr6:8435919 SLC35B3 0.78 11.24 0.52 3.83e-25 Motion sickness; LIHC cis rs1144333 1.000 rs1144333 chr1:76275100 A/G cg10523679 chr1:76189770 ACADM -0.46 -6.73 -0.34 7.26e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs4243830 0.850 rs10779790 chr1:6608435 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.86 -10.83 -0.51 1.07e-23 Body mass index; LIHC cis rs798554 0.757 rs1182181 chr7:2873247 C/G cg04166393 chr7:2884313 GNA12 0.45 6.07 0.31 3.38e-9 Height; LIHC cis rs9296092 0.538 rs62407564 chr6:33534010 C/T cg13560919 chr6:33536144 NA -0.4 -6.57 -0.33 1.92e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7312933 0.558 rs1796382 chr12:42840955 C/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.57 -8.65 -0.42 2.08e-16 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs8084351 0.577 rs12970188 chr18:50650350 A/G cg24270629 chr18:50823537 DCC -0.43 -6.42 -0.33 4.62e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs3892630 1.000 rs3892630 chr19:33181484 A/G cg22980127 chr19:33182716 NUDT19 -1.03 -12.4 -0.56 1.99e-29 Red blood cell traits; LIHC cis rs9303401 0.580 rs12603808 chr17:56578508 T/G cg10487724 chr17:56770010 TEX14;RAD51C 0.98 13.34 0.58 5.74e-33 Cognitive test performance; LIHC cis rs67460515 0.563 rs1599375 chr3:160897771 C/T cg17135325 chr3:160939158 NMD3 -0.58 -8.72 -0.43 1.25e-16 Parkinson's disease; LIHC cis rs748404 0.660 rs493377 chr15:43773467 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.32 0.37 1.76e-12 Lung cancer; LIHC cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.92 0.31 7.63e-9 Schizophrenia; LIHC cis rs10197940 0.624 rs13393122 chr2:152413315 A/G cg06191203 chr2:152266755 RIF1 -0.47 -8.09 -0.4 1.03e-14 Lung cancer; LIHC cis rs244293 1.000 rs244291 chr17:53231137 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.45 -6.52 -0.33 2.5e-10 Menarche (age at onset); LIHC cis rs1707322 0.721 rs10157795 chr1:46228192 G/A cg06784218 chr1:46089804 CCDC17 0.39 7.17 0.36 4.68e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12586317 0.620 rs7147571 chr14:35530236 T/C cg16230307 chr14:35515116 FAM177A1 0.8 13.32 0.58 6.79e-33 Psoriasis; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg21747090 chr2:27597821 SNX17 -0.4 -5.86 -0.3 1.06e-8 Total body bone mineral density; LIHC cis rs10028773 0.546 rs13117947 chr4:120257060 A/G cg09307838 chr4:120376055 NA 0.43 6.36 0.33 6.62e-10 Educational attainment; LIHC cis rs892961 0.932 rs9916143 chr17:75409282 C/G cg05865280 chr17:75406074 SEPT9 -0.61 -12.7 -0.57 1.5e-30 Airflow obstruction; LIHC cis rs12048904 0.595 rs10493937 chr1:101342650 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.72 -12.76 -0.57 9.47e-31 Multiple sclerosis; LIHC cis rs12594515 1.000 rs11854554 chr15:45994546 C/G cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.02 0.55 5.22e-28 Prudent dietary pattern; LIHC trans rs12310956 0.515 rs115836245 chr12:33951369 T/C cg26384229 chr12:38710491 ALG10B 0.44 6.17 0.32 1.9e-9 Morning vs. evening chronotype; LIHC trans rs4650994 0.525 rs4076563 chr1:178516901 C/T cg05059571 chr16:84539110 KIAA1609 -0.45 -7.46 -0.37 7.06e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1559088 0.522 rs7254912 chr19:33554151 A/G cg17764715 chr19:33622953 WDR88 0.53 7.18 0.36 4.34e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26768966 chr19:39807167 LRFN1 -0.34 -6.14 -0.32 2.35e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4631830 0.720 rs4935573 chr10:51504385 A/G cg20129853 chr10:51489980 NA 0.4 8.66 0.42 1.88e-16 Prostate-specific antigen levels; LIHC cis rs2153535 0.580 rs6913100 chr6:8456855 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.52 0.42 5.22e-16 Motion sickness; LIHC cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg20090690 chr10:134436459 INPP5A 0.45 5.8 0.3 1.54e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4466137 0.794 rs6869296 chr5:83007333 C/G cg16102102 chr5:83017553 HAPLN1 0.42 6.78 0.34 5.42e-11 Prostate cancer; LIHC cis rs1892700 0.764 rs12626309 chr21:34888704 A/T cg14850771 chr21:34775459 IFNGR2 0.44 5.85 0.3 1.17e-8 Educational attainment; LIHC cis rs6696846 0.740 rs11240369 chr1:205115099 G/A cg21545522 chr1:205238299 TMCC2 0.32 6.14 0.32 2.29e-9 Red blood cell count; LIHC cis rs2842992 0.830 rs2842966 chr6:160141592 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.98 0.44 1.79e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs35146811 0.961 rs35991721 chr7:99728790 G/T cg22906224 chr7:99728672 NA 0.42 5.85 0.3 1.16e-8 Coronary artery disease; LIHC cis rs8081395 0.741 rs180530 chr17:58003594 G/A cg02344993 chr17:57696989 CLTC 0.35 5.71 0.3 2.44e-8 White blood cell count; LIHC cis rs16854884 0.657 rs12107291 chr3:143739547 T/C cg06585982 chr3:143692056 C3orf58 0.55 7.17 0.36 4.79e-12 Economic and political preferences (feminism/equality); LIHC cis rs80282103 0.867 rs7099063 chr10:1078547 C/G cg20335179 chr10:1068567 C10orf110;IDI2 -0.54 -6.06 -0.31 3.5e-9 Glomerular filtration rate (creatinine); LIHC cis rs11711311 1.000 rs6792447 chr3:113508335 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.14 0.44 5.55e-18 IgG glycosylation; LIHC cis rs10197940 0.624 rs6731486 chr2:152410732 C/T cg06191203 chr2:152266755 RIF1 0.5 9.16 0.44 4.85e-18 Lung cancer; LIHC cis rs1555322 0.530 rs2425043 chr20:33868702 T/C cg17927777 chr20:33865990 NA 0.55 6.53 0.33 2.36e-10 Attention deficit hyperactivity disorder; LIHC cis rs2115630 0.691 rs2292462 chr15:85200754 G/T cg12501888 chr15:85177176 SCAND2 -0.52 -7.98 -0.4 2.27e-14 P wave terminal force; LIHC cis rs910316 0.763 rs175044 chr14:75472109 G/A cg11812906 chr14:75593930 NEK9 -0.75 -14.03 -0.6 1.2e-35 Height; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.58 -8.31 -0.41 2.22e-15 Lymphocyte counts; LIHC cis rs5769765 0.955 rs6520066 chr22:50294988 C/T cg26441486 chr22:50317300 CRELD2 0.34 6.07 0.31 3.31e-9 Schizophrenia; LIHC cis rs2120019 0.938 rs8036573 chr15:75308690 C/T cg11632617 chr15:75315747 PPCDC -0.48 -6.75 -0.34 6.34e-11 Blood trace element (Zn levels); LIHC cis rs1559088 0.947 rs12461219 chr19:33550633 C/G cg17764715 chr19:33622953 WDR88 0.4 5.72 0.3 2.29e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg09033563 chr22:24373618 LOC391322 -0.42 -5.72 -0.3 2.28e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17401966 0.838 rs946503 chr1:10308631 C/G cg15208524 chr1:10270712 KIF1B -0.37 -5.79 -0.3 1.6e-8 Hepatocellular carcinoma; LIHC cis rs7959452 0.535 rs1350166 chr12:69636314 G/T cg20891283 chr12:69753455 YEATS4 0.77 14.11 0.61 6.22e-36 Blood protein levels; LIHC cis rs1801251 1.000 rs10933412 chr2:233707226 G/C cg08000102 chr2:233561755 GIGYF2 -0.77 -11.54 -0.53 3.13e-26 Coronary artery disease; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg06873352 chr17:61820015 STRADA 0.57 8.71 0.43 1.35e-16 Height; LIHC cis rs2777491 0.574 rs316616 chr15:41746276 G/A cg18705301 chr15:41695430 NDUFAF1 -1.22 -18.23 -0.7 2.44e-52 Ulcerative colitis; LIHC cis rs2404602 0.716 rs1588961 chr15:76752698 A/G cg23625390 chr15:77176239 SCAPER 0.37 6.12 0.31 2.54e-9 Blood metabolite levels; LIHC cis rs1003719 0.715 rs2156078 chr21:38546473 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs7107174 1.000 rs1399196 chr11:78071876 A/G cg02023728 chr11:77925099 USP35 0.41 8.0 0.4 1.95e-14 Testicular germ cell tumor; LIHC cis rs10504229 0.610 rs7011877 chr8:58147181 C/T cg21448741 chr8:58168803 NA 0.31 5.87 0.3 1.02e-8 Developmental language disorder (linguistic errors); LIHC cis rs1395 1.000 rs4665958 chr2:27443196 A/G cg23587288 chr2:27483067 SLC30A3 -0.29 -5.72 -0.3 2.28e-8 Blood metabolite levels; LIHC cis rs611744 0.686 rs424976 chr8:109120820 C/A cg21045802 chr8:109455806 TTC35 0.5 8.48 0.42 6.86e-16 Dupuytren's disease; LIHC cis rs17401966 0.931 rs12753426 chr1:10372110 T/C cg15208524 chr1:10270712 KIF1B 0.38 5.84 0.3 1.21e-8 Hepatocellular carcinoma; LIHC cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg05552183 chr6:42928497 GNMT 0.87 13.57 0.59 7.37e-34 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7959452 0.536 rs4761237 chr12:69776461 C/G cg20891283 chr12:69753455 YEATS4 0.9 19.52 0.73 1.56e-57 Blood protein levels; LIHC cis rs12477438 0.501 rs12619780 chr2:99707307 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.63 10.16 0.48 2.37e-21 Chronic sinus infection; LIHC cis rs10504229 1.000 rs112284078 chr8:58191640 A/G cg02290350 chr8:58132656 NA 0.39 7.6 0.38 2.95e-13 Developmental language disorder (linguistic errors); LIHC cis rs11761441 1.000 rs12718067 chr7:82873 T/C cg12845006 chr7:82380 NA 0.32 6.07 0.31 3.32e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs2075371 1.000 rs2598292 chr7:133988584 C/G cg20476274 chr7:133979776 SLC35B4 0.75 12.65 0.56 2.39e-30 Mean platelet volume; LIHC cis rs875971 0.545 rs2420612 chr7:66001812 G/A cg11764359 chr7:65958608 NA 0.62 8.82 0.43 5.9e-17 Aortic root size; LIHC cis rs3020736 0.500 rs7292241 chr22:42492063 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.23 -0.32 1.39e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.593 rs16921589 chr8:58024387 C/A cg20607798 chr8:58055168 NA 0.49 6.94 0.35 2.02e-11 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.790 rs4896852 chr6:146284621 T/C cg23711669 chr6:146136114 FBXO30 -0.71 -12.18 -0.55 1.33e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs6570726 0.791 rs11155433 chr6:145907831 A/G cg23711669 chr6:146136114 FBXO30 -0.66 -11.74 -0.54 5.59e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs9583531 0.574 rs7319459 chr13:111352408 T/C cg24331049 chr13:111365604 ING1 -0.76 -12.75 -0.57 9.88e-31 Coronary artery disease; LIHC cis rs5769765 0.632 rs13056783 chr22:50259152 A/T cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.06 0.44 9.94e-18 Schizophrenia; LIHC cis rs116095464 0.558 rs1971229 chr5:268187 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.58 -0.5 8.03e-23 Breast cancer; LIHC cis rs10791323 0.660 rs10791332 chr11:133732150 A/G cg06766960 chr11:133703094 NA -0.58 -9.25 -0.45 2.51e-18 Childhood ear infection; LIHC cis rs2404602 0.735 rs2461870 chr15:76813920 T/G cg23625390 chr15:77176239 SCAPER -0.49 -8.18 -0.4 5.78e-15 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11567041 chr10:12391824 CAMK1D 0.47 6.63 0.34 1.32e-10 Lung function (FEV1/FVC); LIHC cis rs6818397 1.000 rs6818397 chr4:3434885 A/C cg08741688 chr4:3415352 RGS12 0.42 6.53 0.33 2.37e-10 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs4819052 0.851 rs2838844 chr21:46670733 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 10.94 0.51 4.37e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg18923964 chr14:35451807 SRP54 0.42 6.17 0.32 1.95e-9 Brain volume in infants (cerebrospinal fluid); LIHC trans rs8073060 0.963 rs11080354 chr17:33872407 A/G cg19694781 chr19:47549865 TMEM160 -0.69 -7.63 -0.38 2.34e-13 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg22800045 chr5:56110881 MAP3K1 0.66 8.42 0.41 1.05e-15 Initial pursuit acceleration; LIHC cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg11062466 chr8:58055876 NA 0.5 7.2 0.36 3.82e-12 Developmental language disorder (linguistic errors); LIHC cis rs10791097 0.694 rs2236711 chr11:130739284 G/A cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs986417 0.901 rs1955694 chr14:61020617 G/T cg27398547 chr14:60952738 C14orf39 0.58 6.98 0.35 1.57e-11 Gut microbiota (bacterial taxa); LIHC trans rs1728785 1.000 rs1170433 chr16:68606081 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs1670533 0.932 rs9992925 chr4:1050909 A/T cg27284194 chr4:1044797 NA 0.6 9.02 0.44 1.36e-17 Recombination rate (females); LIHC cis rs7927592 0.956 rs12365160 chr11:68250419 A/G cg20283391 chr11:68216788 NA -0.51 -7.55 -0.38 3.93e-13 Total body bone mineral density; LIHC cis rs2228479 0.717 rs11644967 chr16:89806614 T/A cg19635926 chr16:89946313 TCF25 0.45 5.8 0.3 1.53e-8 Skin colour saturation; LIHC cis rs7937682 0.924 rs513425 chr11:111504861 C/T cg09085632 chr11:111637200 PPP2R1B -1.03 -12.34 -0.56 3.41e-29 Primary sclerosing cholangitis; LIHC cis rs7582720 1.000 rs72934735 chr2:203740010 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1949733 1.000 rs1357481 chr4:8496221 A/T cg11789530 chr4:8429930 ACOX3 0.79 11.84 0.54 2.36e-27 Response to antineoplastic agents; LIHC cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg02187348 chr16:89574699 SPG7 0.53 7.84 0.39 5.8e-14 Multiple myeloma (IgH translocation); LIHC cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg24549020 chr5:56110836 MAP3K1 0.47 6.03 0.31 4.2e-9 Initial pursuit acceleration; LIHC cis rs6500602 0.727 rs11076836 chr16:4569331 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.91 0.3 8.07e-9 Schizophrenia; LIHC cis rs72653721 0.667 rs57729033 chr6:11058436 A/T cg13562911 chr6:11044106 ELOVL2 0.51 7.53 0.38 4.55e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs2286885 1.000 rs10987296 chr9:129245316 C/T cg15282417 chr9:129245246 FAM125B 0.41 6.57 0.33 1.89e-10 Intraocular pressure; LIHC cis rs16828019 0.777 rs16911 chr1:41498021 C/T cg03962019 chr1:41807865 NA 0.49 7.03 0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs870825 0.655 rs28661636 chr4:185634218 A/C cg04058563 chr4:185651563 MLF1IP 0.69 7.29 0.37 2.14e-12 Blood protein levels; LIHC cis rs17401966 1.000 rs58549151 chr1:10314657 A/C cg15208524 chr1:10270712 KIF1B 0.45 6.43 0.33 4.32e-10 Hepatocellular carcinoma; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06623259 chr20:25990680 LOC100134868 0.4 6.49 0.33 3.05e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2531992 0.858 rs2230742 chr16:4016676 C/T cg05927578 chr16:4029543 ADCY9 -0.56 -6.35 -0.32 6.68e-10 Waist circumference; LIHC cis rs7020830 0.830 rs13296413 chr9:37258105 C/T cg14294708 chr9:37120828 ZCCHC7 1.1 23.78 0.79 1.86e-74 Schizophrenia; LIHC cis rs3741404 1.000 rs11603042 chr11:64003843 G/T cg04317338 chr11:64019027 PLCB3 0.59 8.03 0.4 1.64e-14 Platelet count; LIHC cis rs9811920 0.609 rs6765027 chr3:99687730 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.12 0.36 6.3e-12 Axial length; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg22199361 chr20:5081567 C20orf30 -0.48 -6.35 -0.32 6.7e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12477438 0.508 rs2516832 chr2:99771268 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.46 0.77 2.71e-69 Chronic sinus infection; LIHC cis rs3815700 0.844 rs444089 chr19:33106991 G/C cg02997394 chr19:33096574 ANKRD27 0.61 7.39 0.37 1.1e-12 Eosinophilic esophagitis; LIHC cis rs9921222 0.500 rs12917907 chr16:405866 C/T cg26913058 chr16:419975 MRPL28 -0.43 -5.76 -0.3 1.89e-8 Bone mineral density (spine);Bone mineral density; LIHC cis rs5769765 0.955 rs61136468 chr22:50312679 A/G cg02269571 chr22:50332266 NA -0.61 -8.57 -0.42 3.63e-16 Schizophrenia; LIHC cis rs2832191 0.720 rs2832194 chr21:30494250 T/C cg24692254 chr21:30365293 RNF160 -0.6 -10.47 -0.49 1.94e-22 Dental caries; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20552752 chr15:90895281 ZNF774 0.43 6.29 0.32 9.67e-10 Pancreatic cancer; LIHC cis rs12762955 0.561 rs2620942 chr10:1048398 C/T cg18964960 chr10:1102726 WDR37 0.53 5.86 0.3 1.07e-8 Response to angiotensin II receptor blocker therapy; LIHC cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg27572855 chr1:25598939 RHD 0.4 8.48 0.42 6.71e-16 Plateletcrit;Mean corpuscular volume; LIHC cis rs1023500 0.573 rs2413666 chr22:42459622 C/T cg15557168 chr22:42548783 NA -0.41 -6.41 -0.33 4.94e-10 Schizophrenia; LIHC cis rs3744061 0.505 rs9915915 chr17:74652274 A/G cg13533061 chr17:74712429 JMJD6 -0.28 -5.72 -0.3 2.39e-8 Retinal arteriolar caliber; LIHC cis rs17253792 0.822 rs75016910 chr14:56050466 C/G cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs2836950 0.565 rs2836943 chr21:40592611 C/T cg06238570 chr21:40685208 BRWD1 -0.41 -6.42 -0.33 4.43e-10 Menarche (age at onset); LIHC trans rs6489882 0.807 rs10774677 chr12:113362421 G/A cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.97e-10 Chronic lymphocytic leukemia; LIHC cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs6445975 0.667 rs2037123 chr3:58239193 G/T cg23715586 chr3:58305044 RPP14 -0.34 -5.74 -0.3 2.13e-8 Systemic lupus erythematosus; LIHC cis rs992157 0.965 rs13419763 chr2:219134950 C/T cg00012203 chr2:219082015 ARPC2 0.87 14.33 0.61 8.61e-37 Colorectal cancer; LIHC cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg11663144 chr21:46675770 NA -0.32 -6.0 -0.31 4.95e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3749237 0.595 rs7643845 chr3:49530711 A/G cg03060546 chr3:49711283 APEH 0.63 10.23 0.48 1.35e-21 Resting heart rate; LIHC cis rs11626933 1.000 rs6575122 chr14:90753556 A/G cg14092571 chr14:90743983 NA -0.9 -14.83 -0.63 9.11e-39 Gut microbiota (bacterial taxa); LIHC cis rs12497850 0.931 rs9840050 chr3:49133310 A/G cg06212747 chr3:49208901 KLHDC8B 0.59 7.68 0.38 1.74e-13 Parkinson's disease; LIHC cis rs2303745 0.589 rs751599 chr19:17396549 A/G cg02221750 chr19:17393354 ANKLE1 -0.45 -6.38 -0.33 5.86e-10 Systemic lupus erythematosus; LIHC cis rs7739232 0.920 rs6941645 chr6:53515130 A/G cg15658676 chr6:53530538 KLHL31 -0.91 -6.63 -0.34 1.3e-10 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs1144333 1.000 rs5745343 chr1:76273805 A/G cg22875332 chr1:76189707 ACADM -0.41 -6.87 -0.35 3.1e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs6754311 0.731 rs745500 chr2:136583192 G/A cg07305463 chr2:136567211 LCT 0.39 7.49 0.38 6.05e-13 Mosquito bite size; LIHC cis rs9309473 0.607 rs7560272 chr2:73561485 A/T cg20560298 chr2:73613845 ALMS1 -0.45 -7.22 -0.36 3.3e-12 Metabolite levels; LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg07424592 chr7:64974309 NA 0.41 6.2 0.32 1.67e-9 Calcium levels; LIHC cis rs17106184 1.000 rs59786222 chr1:51295793 C/T cg07174182 chr1:51127561 FAF1 -0.61 -6.85 -0.35 3.54e-11 Type 2 diabetes; LIHC trans rs7726839 0.540 rs7434 chr5:660804 A/G cg25482853 chr8:67687455 SGK3 -0.6 -6.04 -0.31 3.93e-9 Obesity-related traits; LIHC cis rs10504229 0.679 rs16921623 chr8:58039473 G/C cg02290350 chr8:58132656 NA 0.32 7.07 0.36 8.87e-12 Developmental language disorder (linguistic errors); LIHC cis rs4660261 0.562 rs3011223 chr1:44318286 T/C cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.768 rs2273824 chr6:160211445 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs4268898 1.000 rs4268898 chr2:24490413 C/T cg06627628 chr2:24431161 ITSN2 0.52 7.52 0.38 4.9e-13 Asthma; LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg02951883 chr7:2050386 MAD1L1 -0.76 -13.15 -0.58 3.05e-32 Bipolar disorder and schizophrenia; LIHC cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg03806693 chr22:41940476 POLR3H -1.04 -12.19 -0.55 1.27e-28 Vitiligo; LIHC cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg18876405 chr7:65276391 NA 0.55 9.39 0.45 8.94e-19 Aortic root size; LIHC cis rs3806843 0.900 rs116210441 chr5:140128649 T/A cg19875535 chr5:140030758 IK -0.35 -5.72 -0.3 2.32e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1387259 0.929 rs2634666 chr12:48663670 G/T cg21466736 chr12:48725269 NA -0.72 -10.97 -0.51 3.37e-24 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs34390795 1 rs34390795 chr12:133112394 CGT/C cg06183872 chr12:133049993 NA 0.35 5.97 0.31 5.97e-9 Red blood cell count; LIHC cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.45e-8 Alzheimer's disease; LIHC cis rs2439831 0.681 rs3742969 chr15:43621947 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.78 11.88 0.54 1.7e-27 Lung cancer in ever smokers; LIHC cis rs11690935 0.632 rs2292816 chr2:172586714 G/C cg13550731 chr2:172543902 DYNC1I2 0.64 11.65 0.53 1.24e-26 Schizophrenia; LIHC cis rs17539620 0.628 rs62432728 chr6:154829511 G/C cg20019720 chr6:154832845 CNKSR3 0.44 6.49 0.33 2.97e-10 Lipoprotein (a) levels; LIHC cis rs10752881 0.967 rs12404594 chr1:182988027 G/A ch.1.3577855R chr1:183094577 LAMC1 0.58 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs881375 0.967 rs7046108 chr9:123660339 A/G cg14580859 chr9:123691850 NA -0.38 -6.63 -0.34 1.33e-10 Rheumatoid arthritis; LIHC cis rs11122272 0.735 rs2437147 chr1:231516756 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs1707322 0.686 rs2991987 chr1:46081422 C/G cg03146154 chr1:46216737 IPP -0.57 -9.59 -0.46 1.96e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1559088 1.000 rs11672313 chr19:33563190 C/T cg17764715 chr19:33622953 WDR88 0.41 5.72 0.3 2.35e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1451375 0.652 rs7779110 chr7:50625651 T/C cg14593290 chr7:50529359 DDC 0.49 7.86 0.39 5.03e-14 Malaria; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13108601 chr6:41748242 FRS3;PRICKLE4 0.44 6.48 0.33 3.16e-10 Pancreatic cancer; LIHC cis rs801193 0.569 rs4717315 chr7:66178325 C/T cg11764359 chr7:65958608 NA 0.76 12.98 0.57 1.3e-31 Aortic root size; LIHC cis rs765787 0.530 rs4238377 chr15:45541981 A/G cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC cis rs4665809 1.000 rs17040322 chr2:26351274 G/C cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs10423674 0.526 rs12462498 chr19:18832950 A/G cg14292368 chr19:18793705 CRTC1 0.41 5.82 0.3 1.38e-8 Menarche (age at onset); LIHC trans rs60843830 0.928 rs62114494 chr2:211317 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.58 7.89 0.39 4.22e-14 Spherical equivalent (joint analysis main effects and education interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18429434 chr2:203499731 FAM117B -0.47 -6.06 -0.31 3.61e-9 Systolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03120789 chr1:20208808 OTUD3 0.51 7.07 0.36 8.63e-12 Pancreatic cancer; LIHC cis rs875971 0.619 rs10278371 chr7:66051540 C/A cg11764359 chr7:65958608 NA -0.71 -10.21 -0.48 1.55e-21 Aortic root size; LIHC cis rs1707322 0.964 rs785508 chr1:46527159 G/A cg03146154 chr1:46216737 IPP -0.45 -7.4 -0.37 1.03e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7762018 0.891 rs4716343 chr6:170143817 C/G cg19338460 chr6:170058176 WDR27 -0.37 -5.76 -0.3 1.9e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs66887589 0.616 rs11732621 chr4:120212883 A/C cg25214090 chr10:38739885 LOC399744 0.43 6.86 0.35 3.18e-11 Diastolic blood pressure; LIHC trans rs875971 0.638 rs3898855 chr7:66036398 G/C cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC cis rs6754311 0.731 rs2164210 chr2:136580287 T/C cg07305463 chr2:136567211 LCT 0.39 7.54 0.38 4.34e-13 Mosquito bite size; LIHC cis rs67311347 1.000 rs2305521 chr3:40429183 A/G cg00656387 chr3:40428638 ENTPD3 0.39 6.43 0.33 4.41e-10 Renal cell carcinoma; LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.522 rs289643 chr10:37941494 T/G cg25427524 chr10:38739819 LOC399744 -0.6 -11.34 -0.52 1.58e-25 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.616 rs1607852 chr12:38398125 G/A cg26384229 chr12:38710491 ALG10B 0.84 10.51 0.49 1.45e-22 Bladder cancer; LIHC cis rs860295 0.812 rs7556519 chr1:155827546 T/C cg02153340 chr1:155202674 NA -0.33 -6.08 -0.31 3.28e-9 Body mass index; LIHC cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg06634786 chr22:41940651 POLR3H -0.75 -8.2 -0.41 5.01e-15 Vitiligo; LIHC cis rs7772486 0.875 rs865913 chr6:146308874 C/T cg23711669 chr6:146136114 FBXO30 0.67 11.43 0.53 7.61e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs61931739 0.534 rs7133262 chr12:34279444 G/A cg26384229 chr12:38710491 ALG10B 0.56 7.11 0.36 6.66e-12 Morning vs. evening chronotype; LIHC cis rs1552244 0.816 rs13059144 chr3:10010197 A/C cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs9837602 0.507 rs793455 chr3:99526135 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.49 6.95 0.35 1.87e-11 Breast cancer; LIHC cis rs3736485 0.934 rs8038203 chr15:51870683 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1.05e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13559233 chr1:82269258 LPHN2 -0.33 -6.13 -0.31 2.41e-9 Cognitive function; LIHC trans rs1005277 0.522 rs200943 chr10:38148730 A/G cg23533926 chr12:111358616 MYL2 -0.33 -6.47 -0.33 3.34e-10 Extrinsic epigenetic age acceleration; LIHC cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.85 0.3 1.12e-8 Menopause (age at onset); LIHC cis rs2346268 0.605 rs13310832 chr7:133646213 T/G cg03336402 chr7:133662267 EXOC4 -0.46 -5.74 -0.3 2.06e-8 Intelligence (multi-trait analysis); LIHC cis rs1062177 1.000 rs2915887 chr5:151205504 C/T cg00977110 chr5:151150581 G3BP1 0.52 6.52 0.33 2.55e-10 Preschool internalizing problems; LIHC cis rs12022452 0.591 rs4660415 chr1:40978491 C/A cg25568243 chr1:40974465 DEM1 0.45 6.09 0.31 2.95e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs854765 0.647 rs7212447 chr17:17987067 G/A cg04398451 chr17:18023971 MYO15A -0.66 -10.91 -0.51 5.48e-24 Total body bone mineral density; LIHC trans rs72960926 0.744 rs7776273 chr6:74967693 T/C cg07247405 chr1:2484626 LOC115110 0.53 6.31 0.32 8.75e-10 Metabolite levels (MHPG); LIHC cis rs4908760 0.539 rs7513880 chr1:8839300 G/A cg20416874 chr1:8611966 RERE -0.57 -10.22 -0.48 1.47e-21 Vitiligo; LIHC trans rs11098499 1.000 rs11098500 chr4:120219239 T/A cg25214090 chr10:38739885 LOC399744 0.51 7.86 0.39 5.14e-14 Corneal astigmatism; LIHC cis rs4891159 0.756 rs8084155 chr18:74134952 A/G cg24786174 chr18:74118243 ZNF516 -0.82 -16.32 -0.66 1.11e-44 Longevity; LIHC trans rs1814175 0.765 rs1794141 chr11:49914135 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs4319547 0.695 rs10846746 chr12:122868696 C/T cg23029597 chr12:123009494 RSRC2 0.51 7.28 0.37 2.3e-12 Body mass index; LIHC cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.51e-29 Menopause (age at onset); LIHC cis rs4819052 0.851 rs13050359 chr21:46672671 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.82 0.39 6.79e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs644148 0.836 rs2686770 chr19:44998773 A/G cg15540054 chr19:45004280 ZNF180 -0.72 -10.61 -0.5 6.15e-23 Personality dimensions; LIHC cis rs763121 0.853 rs4821798 chr22:39021165 T/C cg21395723 chr22:39101663 GTPBP1 0.42 7.11 0.36 6.62e-12 Menopause (age at onset); LIHC cis rs60871478 1.000 rs34761279 chr7:794471 A/G cg04727924 chr7:799746 HEATR2 -0.63 -8.58 -0.42 3.4e-16 Cerebrospinal P-tau181p levels; LIHC cis rs1110701 0.525 rs11764792 chr7:50496841 C/T cg18232548 chr7:50535776 DDC -0.43 -6.28 -0.32 1.05e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC trans rs10988449 1.000 rs55700157 chr9:132371965 C/A cg08482979 chr16:88858277 NA -0.5 -6.08 -0.31 3.29e-9 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs7107174 1.000 rs10899456 chr11:78000155 C/G cg02023728 chr11:77925099 USP35 0.49 9.47 0.46 4.89e-19 Testicular germ cell tumor; LIHC cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg16606324 chr3:10149918 C3orf24 0.53 5.77 0.3 1.73e-8 Alzheimer's disease; LIHC cis rs9457247 0.967 rs385460 chr6:167403888 A/T cg12798992 chr6:167411361 FGFR1OP 0.6 10.02 0.48 6.67e-21 Crohn's disease; LIHC cis rs826838 0.933 rs1906263 chr12:38653362 T/C cg13010199 chr12:38710504 ALG10B 0.62 7.46 0.37 7.15e-13 Heart rate; LIHC trans rs7618501 0.602 rs2301166 chr3:50148305 C/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.14 -0.44 5.47e-18 Intelligence (multi-trait analysis); LIHC cis rs13256369 0.901 rs12681298 chr8:8566235 A/G cg17143192 chr8:8559678 CLDN23 -0.75 -13.25 -0.58 1.26e-32 Obesity-related traits; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg18128437 chr3:167453397 PDCD10;SERPINI1 0.46 6.57 0.33 1.92e-10 Migraine with aura; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.5 -6.2 -0.32 1.66e-9 Diastolic blood pressure; LIHC cis rs7833986 0.501 rs9650314 chr8:56903610 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.82 8.33 0.41 1.92e-15 Height; LIHC cis rs208520 0.690 rs10944872 chr6:66708239 T/G cg07460842 chr6:66804631 NA 0.71 8.4 0.41 1.24e-15 Exhaled nitric oxide output; LIHC cis rs7635838 0.617 rs2606731 chr3:11291615 A/C cg00170343 chr3:11313890 ATG7 0.54 8.47 0.42 7.31e-16 HDL cholesterol; LIHC cis rs7520050 0.931 rs11211198 chr1:46282673 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.98 0.31 5.65e-9 Red blood cell count;Reticulocyte count; LIHC cis rs72634258 0.554 rs12723500 chr1:7857374 G/C cg26816564 chr1:7831052 VAMP3 0.64 5.95 0.31 6.51e-9 Inflammatory bowel disease; LIHC cis rs1003719 0.708 rs3787788 chr21:38502804 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.23 -0.52 4.16e-25 Eye color traits; LIHC cis rs3762637 1.000 rs9878699 chr3:122194231 T/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs67981189 0.574 rs8004452 chr14:71416040 G/A cg15816911 chr14:71606274 NA -0.42 -6.6 -0.34 1.59e-10 Schizophrenia; LIHC cis rs473651 0.935 rs472357 chr2:239355454 A/G cg18131467 chr2:239335373 ASB1 -1.05 -19.66 -0.73 3.92e-58 Multiple system atrophy; LIHC cis rs9328573 0.967 rs12441141 chr15:100509976 C/A cg09918751 chr15:100517450 ADAMTS17 -0.49 -7.35 -0.37 1.46e-12 Urate levels in lean individuals; LIHC cis rs7959452 0.640 rs4761233 chr12:69722880 T/C cg20891283 chr12:69753455 YEATS4 0.8 15.24 0.64 2.16e-40 Blood protein levels; LIHC cis rs7249142 0.562 rs1050544 chr19:19287901 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.36 -6.02 -0.31 4.45e-9 IgG glycosylation; LIHC cis rs72627509 0.904 rs58408429 chr4:57769824 T/C cg16868167 chr4:57843880 C4orf14;POLR2B -0.54 -7.87 -0.39 4.72e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg05025164 chr4:1340916 KIAA1530 -0.65 -9.76 -0.47 5.19e-20 Obesity-related traits; LIHC cis rs2073300 0.609 rs6132610 chr20:23403987 C/T cg16736954 chr20:23401023 NAPB 0.72 8.46 0.42 7.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3617 0.625 rs2071042 chr3:52864584 A/G cg11645453 chr3:52864694 ITIH4 0.22 5.95 0.31 6.65e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs7789940 0.904 rs7459185 chr7:75934640 C/G cg10167463 chr7:75959203 YWHAG 0.43 6.88 0.35 2.82e-11 Multiple sclerosis; LIHC cis rs758324 0.947 rs6861732 chr5:131156462 A/C cg06307176 chr5:131281290 NA 0.4 5.82 0.3 1.33e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg26818010 chr10:134567672 INPP5A -0.77 -9.45 -0.46 5.46e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11105298 0.891 rs10858871 chr12:89871613 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.54 -0.38 4.24e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs9814567 0.752 rs7633868 chr3:134331048 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs143000161 1 rs143000161 chr2:165710540 A/T cg03182029 chr2:165697222 COBLL1 0.9 6.87 0.35 2.99e-11 Heschl's gyrus morphology; LIHC cis rs801193 1.000 rs11773829 chr7:66141074 G/A cg11764359 chr7:65958608 NA -0.71 -10.63 -0.5 5.35e-23 Aortic root size; LIHC cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg16405210 chr4:1374714 KIAA1530 0.42 6.27 0.32 1.1e-9 Obesity-related traits; LIHC cis rs3106136 0.967 rs767657 chr4:95227901 G/T cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.51 -0.38 5.15e-13 Capecitabine sensitivity; LIHC trans rs7618501 1.000 rs6446295 chr3:49809063 G/T cg21582582 chr3:182698605 DCUN1D1 0.53 6.89 0.35 2.62e-11 Intelligence (multi-trait analysis); LIHC cis rs727563 0.593 rs5758461 chr22:42162189 G/C cg03806693 chr22:41940476 POLR3H 0.98 10.31 0.49 7.06e-22 Crohn's disease;Inflammatory bowel disease; LIHC cis rs8062405 0.690 rs762634 chr16:28603335 T/C cg00204512 chr16:28754710 NA 0.42 7.09 0.36 7.97e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs614226 0.938 rs7972244 chr12:120994872 A/G cg01236616 chr12:121019343 POP5 1.26 18.82 0.71 9.63e-55 Type 1 diabetes nephropathy; LIHC cis rs965469 1.000 rs2236118 chr20:3302058 C/T cg25506879 chr20:3388711 C20orf194 -0.57 -6.81 -0.35 4.29e-11 IFN-related cytopenia; LIHC trans rs1814175 0.817 rs4881658 chr11:49941123 G/A cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs6684514 0.961 rs11264463 chr1:156242806 A/G cg16558208 chr1:156270281 VHLL 0.53 10.07 0.48 4.71e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg11644478 chr21:40555479 PSMG1 0.81 10.3 0.49 7.59e-22 Cognitive function; LIHC cis rs2066819 1.000 rs77853814 chr12:56687572 G/T cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg00476317 chr8:12990213 DLC1 0.74 6.72 0.34 7.72e-11 Musician's dystonia; LIHC cis rs7267979 1.000 rs2259873 chr20:25280781 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs11628318 0.853 rs28444760 chr14:103041148 A/G cg01864069 chr14:103024347 NA -0.57 -9.52 -0.46 3.36e-19 Platelet count; LIHC cis rs2832191 1.000 rs9984793 chr21:30486471 T/C cg24692254 chr21:30365293 RNF160 -0.64 -11.4 -0.52 9.9e-26 Dental caries; LIHC cis rs6450176 0.909 rs10940353 chr5:53299959 A/C ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.6 -0.62 7.2e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg13126279 chr21:47581558 C21orf56 -0.45 -7.36 -0.37 1.35e-12 Testicular germ cell tumor; LIHC cis rs1949733 1.000 rs868105 chr4:8501030 G/T cg11789530 chr4:8429930 ACOX3 -0.78 -11.79 -0.54 3.65e-27 Response to antineoplastic agents; LIHC cis rs7408868 1.000 rs10420466 chr19:15261371 G/T cg14696996 chr19:15285081 NOTCH3 0.48 6.24 0.32 1.28e-9 Pulse pressure; LIHC cis rs7927592 0.913 rs7127948 chr11:68363062 G/A cg16797656 chr11:68205561 LRP5 0.5 7.78 0.39 8.43e-14 Total body bone mineral density; LIHC cis rs9534288 0.797 rs2896951 chr13:46581185 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs1577917 0.958 rs10806337 chr6:86474249 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.97 -0.51 3.35e-24 Response to antipsychotic treatment; LIHC cis rs1559088 0.895 rs7259582 chr19:33593979 A/G cg27124370 chr19:33622961 WDR88 0.53 8.26 0.41 3.19e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.94 9.17 0.44 4.47e-18 Platelet count; LIHC cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg06238570 chr21:40685208 BRWD1 0.61 7.43 0.37 9e-13 Cognitive function; LIHC cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg11301795 chr4:187892539 NA -0.26 -6.99 -0.35 1.44e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg04546413 chr19:29218101 NA 0.54 10.49 0.49 1.61e-22 Methadone dose in opioid dependence; LIHC cis rs17685 0.753 rs13240967 chr7:75658197 C/T cg04610667 chr7:75704037 NA 0.34 6.04 0.31 3.96e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7395581 0.918 rs11039166 chr11:47316691 A/C cg25783544 chr11:47291846 MADD 0.42 6.15 0.32 2.18e-9 HDL cholesterol; LIHC cis rs36051895 0.589 rs7848312 chr9:5237442 T/C cg02405213 chr9:5042618 JAK2 -0.66 -10.64 -0.5 5.12e-23 Pediatric autoimmune diseases; LIHC cis rs1256061 0.603 rs1256044 chr14:64734027 G/A cg23250157 chr14:64679961 SYNE2 0.4 6.03 0.31 4.25e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs1862618 0.613 rs252889 chr5:56227069 C/A cg12311346 chr5:56204834 C5orf35 -0.46 -6.27 -0.32 1.09e-9 Initial pursuit acceleration; LIHC cis rs780096 0.545 rs11695549 chr2:27586155 A/C cg05484376 chr2:27715224 FNDC4 0.38 6.3 0.32 9.25e-10 Total body bone mineral density; LIHC cis rs17125944 1.000 rs17125944 chr14:53400629 C/T cg00686598 chr14:53173677 PSMC6 -0.77 -8.36 -0.41 1.63e-15 Alzheimer's disease (late onset); LIHC cis rs758324 0.947 rs60847707 chr5:131252554 C/T cg06307176 chr5:131281290 NA -0.4 -5.82 -0.3 1.33e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg02990361 chr1:107599529 PRMT6 0.64 10.65 0.5 4.71e-23 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs1814175 0.647 rs10839394 chr11:49844747 T/C cg15704280 chr7:45808275 SEPT13 -1.0 -21.89 -0.76 4.85e-67 Height; LIHC cis rs8180040 0.726 rs1869871 chr3:47023948 C/T cg27129171 chr3:47204927 SETD2 0.6 9.99 0.48 8.97e-21 Colorectal cancer; LIHC cis rs7027203 0.663 rs4428726 chr9:96623559 T/G cg13679303 chr9:96623674 NA -0.3 -6.74 -0.34 6.92e-11 DNA methylation (variation); LIHC cis rs765787 0.530 rs4775819 chr15:45525966 C/T cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.78 -0.3 1.71e-8 Uric acid levels; LIHC trans rs9929218 1.000 rs13334326 chr16:68809207 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs2439831 1.000 rs2584725 chr15:43793135 T/C cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.34e-9 Lung cancer in ever smokers; LIHC cis rs2836950 0.565 rs2836934 chr21:40564885 A/C cg17971929 chr21:40555470 PSMG1 -0.39 -5.91 -0.3 8.36e-9 Menarche (age at onset); LIHC cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 7.64 0.38 2.14e-13 Platelet count; LIHC cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg12373951 chr3:133503437 NA 0.54 9.3 0.45 1.73e-18 Iron status biomarkers; LIHC cis rs77861329 1.000 rs171294 chr3:52203599 C/G cg08692210 chr3:52188851 WDR51A 0.83 7.86 0.39 5.11e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs1577917 1.000 rs12212733 chr6:86726013 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.83 -0.35 3.86e-11 Response to antipsychotic treatment; LIHC cis rs4819052 0.851 rs7276103 chr21:46666078 G/A cg22633049 chr21:46681294 NA -0.35 -6.06 -0.31 3.59e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs78545713 0.649 rs79988778 chr6:26210621 G/T cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.91 0.54 1.41e-27 Prudent dietary pattern; LIHC cis rs7131987 0.650 rs7301398 chr12:29455390 G/T cg05697976 chr12:29376483 FAR2 0.29 5.99 0.31 5.43e-9 QT interval; LIHC cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg20887711 chr4:1340912 KIAA1530 0.64 9.62 0.46 1.5e-19 Longevity; LIHC cis rs6430585 0.583 rs4988163 chr2:136628121 G/T cg07169764 chr2:136633963 MCM6 1.24 21.06 0.75 1e-63 Corneal structure; LIHC cis rs17270561 0.583 rs6908407 chr6:25703656 A/T cg17691542 chr6:26056736 HIST1H1C -0.44 -5.94 -0.31 7.1e-9 Iron status biomarkers; LIHC cis rs7772486 0.875 rs1125461 chr6:146417653 C/T cg13319975 chr6:146136371 FBXO30 -0.38 -6.09 -0.31 2.99e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7674212 0.570 rs6841136 chr4:104103509 A/C cg16532752 chr4:104119610 CENPE -0.47 -7.32 -0.37 1.78e-12 Type 2 diabetes; LIHC cis rs734999 0.588 rs2985859 chr1:2532416 T/C cg18854424 chr1:2615690 NA -0.32 -7.11 -0.36 6.83e-12 Ulcerative colitis; LIHC cis rs7729447 0.804 rs116090595 chr5:32698148 T/G cg16267343 chr5:32710456 NPR3 0.47 5.82 0.3 1.35e-8 Blood pressure; LIHC trans rs875971 0.638 rs6960778 chr7:66071597 C/T cg26939375 chr7:64535504 NA -0.44 -7.05 -0.36 1.01e-11 Aortic root size; LIHC cis rs8177179 0.967 rs4994582 chr3:133437566 G/C cg16262614 chr3:133464971 TF 0.45 10.22 0.48 1.46e-21 Iron status biomarkers (transferrin levels); LIHC cis rs922107 0.738 rs12124338 chr1:90053167 A/G cg15422784 chr1:90023713 LRRC8B -0.49 -7.78 -0.39 8.58e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs80282103 0.764 rs12247818 chr10:1110464 G/A cg18964960 chr10:1102726 WDR37 0.67 6.11 0.31 2.72e-9 Glomerular filtration rate (creatinine); LIHC cis rs9916302 0.904 rs6503506 chr17:37524653 C/A cg03013999 chr17:37608204 MED1 -0.35 -5.9 -0.3 8.64e-9 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs79839061 0.610 rs62297087 chr4:913289 T/A cg07828340 chr4:882639 GAK 0.8 6.22 0.32 1.46e-9 Intelligence (multi-trait analysis); LIHC cis rs12644436 0.628 rs1599720 chr4:88782714 G/A cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg21448741 chr8:58168803 NA 0.37 6.66 0.34 1.09e-10 Developmental language disorder (linguistic errors); LIHC cis rs9393692 0.840 rs9358915 chr6:26277268 G/A cg00631329 chr6:26305371 NA -0.43 -7.25 -0.36 2.88e-12 Educational attainment; LIHC cis rs17152411 1.000 rs17152411 chr10:126649516 A/G cg07906193 chr10:126599966 NA 0.45 7.22 0.36 3.43e-12 Height; LIHC cis rs4975616 0.804 rs462608 chr5:1336626 T/A cg07493874 chr5:1342172 CLPTM1L -0.65 -10.38 -0.49 4e-22 Lung cancer; LIHC cis rs9394841 0.667 rs1891453 chr6:41765265 T/C cg17623882 chr6:41773611 USP49 -0.44 -5.85 -0.3 1.15e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs7572733 0.555 rs1837495 chr2:198921201 A/G cg03934865 chr2:198174659 NA -0.45 -6.48 -0.33 3.15e-10 Dermatomyositis; LIHC cis rs7607369 0.791 rs72965151 chr2:219344165 G/T cg02985541 chr2:219472218 PLCD4 -0.43 -6.94 -0.35 1.93e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg17372223 chr3:52568218 NT5DC2 -0.37 -5.73 -0.3 2.18e-8 Bipolar disorder; LIHC cis rs60871478 1.000 rs62432250 chr7:801792 C/G cg13844804 chr7:814759 HEATR2 0.44 5.93 0.31 7.37e-9 Cerebrospinal P-tau181p levels; LIHC cis rs7937682 0.663 rs7116280 chr11:111659111 T/C cg09085632 chr11:111637200 PPP2R1B 0.96 14.34 0.61 7.3e-37 Primary sclerosing cholangitis; LIHC trans rs1994135 0.715 rs10506110 chr12:33708552 A/C cg26384229 chr12:38710491 ALG10B 0.47 6.37 0.33 6.01e-10 Resting heart rate; LIHC cis rs10078 0.571 rs2721014 chr5:463539 G/A cg24955955 chr5:415729 AHRR 0.59 11.17 0.52 6.81e-25 Fat distribution (HIV); LIHC cis rs778371 0.723 rs12999865 chr2:233627250 T/C cg08000102 chr2:233561755 GIGYF2 0.88 14.79 0.62 1.35e-38 Schizophrenia; LIHC cis rs3806843 1.000 rs11167609 chr5:140200426 T/G cg26395211 chr5:140044315 WDR55 -0.42 -6.23 -0.32 1.39e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs35306767 0.715 rs17221456 chr10:1037234 T/C cg26597838 chr10:835615 NA 0.92 8.65 0.42 1.96e-16 Eosinophil percentage of granulocytes; LIHC cis rs2404602 0.692 rs1471780 chr15:77026526 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.68e-9 Blood metabolite levels; LIHC cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg00750074 chr16:89608354 SPG7 -0.49 -8.02 -0.4 1.74e-14 Multiple myeloma (IgH translocation); LIHC cis rs17401966 1.000 rs11121532 chr1:10277898 G/T cg19773385 chr1:10388646 KIF1B -0.48 -8.15 -0.4 7.07e-15 Hepatocellular carcinoma; LIHC cis rs7312933 0.558 rs1796381 chr12:42842475 C/T cg01256987 chr12:42539512 GXYLT1 -0.34 -5.81 -0.3 1.4e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4699052 0.963 rs2061646 chr4:104183894 T/C cg16532752 chr4:104119610 CENPE -0.4 -6.33 -0.32 7.56e-10 Testicular germ cell tumor; LIHC cis rs2067615 0.560 rs10861671 chr12:107220927 T/C cg15890332 chr12:107067104 RFX4 0.27 6.24 0.32 1.32e-9 Heart rate; LIHC cis rs17286411 0.639 rs12447856 chr16:71790673 A/G cg06353428 chr16:71660113 MARVELD3 -0.39 -5.83 -0.3 1.25e-8 Blood protein levels; LIHC cis rs7904368 0.806 rs6602161 chr10:16862280 A/G cg23933602 chr10:16859644 RSU1 0.6 5.91 0.3 8.29e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs9303280 0.901 rs9901146 chr17:38043343 G/A cg11212589 chr17:38028394 ZPBP2 0.38 7.96 0.4 2.59e-14 Self-reported allergy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15613982 chr20:18488017 SEC23B 0.45 6.7 0.34 8.38e-11 Pancreatic cancer; LIHC cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg11062466 chr8:58055876 NA 0.47 6.01 0.31 4.83e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 0.901 rs73142137 chr7:65343442 A/T cg18252515 chr7:66147081 NA -1.3 -16.6 -0.67 8.39e-46 Diabetic kidney disease; LIHC trans rs1814175 0.541 rs12287397 chr11:49819799 G/A cg03929089 chr4:120376271 NA -0.9 -18.56 -0.71 1.09e-53 Height; LIHC cis rs2228479 0.850 rs17226512 chr16:89839976 T/C cg04013166 chr16:89971882 TCF25 0.52 6.62 0.34 1.35e-10 Skin colour saturation; LIHC cis rs870825 0.616 rs4519834 chr4:185633865 A/G cg04058563 chr4:185651563 MLF1IP -0.69 -7.07 -0.36 8.72e-12 Blood protein levels; LIHC cis rs67478160 0.679 rs7156834 chr14:104211180 G/A cg01849466 chr14:104193079 ZFYVE21 -0.44 -7.0 -0.35 1.36e-11 Schizophrenia; LIHC cis rs6138458 1.000 rs227618 chr20:24909472 T/C cg26195577 chr20:24973756 C20orf3 1.1 13.84 0.6 6.94e-35 Blood protein levels; LIHC cis rs1707322 1.000 rs4298677 chr1:46306619 G/A cg06784218 chr1:46089804 CCDC17 0.37 6.59 0.34 1.62e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7107174 0.892 rs10899490 chr11:78105879 C/T cg02023728 chr11:77925099 USP35 0.41 7.71 0.38 1.39e-13 Testicular germ cell tumor; LIHC cis rs1552244 0.882 rs56332224 chr3:10037321 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.51 0.49 1.4e-22 Alzheimer's disease; LIHC cis rs881375 0.678 rs2269060 chr9:123683569 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.42 6.22 0.32 1.41e-9 Rheumatoid arthritis; LIHC cis rs2370759 1.000 rs11599522 chr10:32568434 G/C cg05361325 chr10:32636312 EPC1 -0.51 -6.24 -0.32 1.31e-9 Sexual dysfunction (female); LIHC trans rs1814175 0.765 rs1722003 chr11:49895896 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.94 0.35 2.01e-11 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14166846 chr1:220268091 IARS2 0.4 6.66 0.34 1.07e-10 Cognitive function; LIHC cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg13877915 chr19:58951672 ZNF132 0.63 10.65 0.5 4.45e-23 Uric acid clearance; LIHC cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg15691649 chr6:25882328 NA -0.63 -8.47 -0.42 7.42e-16 Intelligence (multi-trait analysis); LIHC trans rs6058796 1.000 rs6087406 chr20:31241025 G/T cg02600331 chr11:130417168 NA 0.35 6.26 0.32 1.18e-9 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.9 -10.45 -0.49 2.22e-22 Platelet count; LIHC cis rs1707322 1.000 rs12124291 chr1:46432132 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.36 0.33 6.54e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9394841 0.692 rs13193235 chr6:41792659 T/C cg17623882 chr6:41773611 USP49 -0.43 -5.74 -0.3 2.09e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs736408 0.812 rs746694 chr3:52826620 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 5.88 0.3 9.5e-9 Bipolar disorder; LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg26338869 chr17:61819248 STRADA 0.6 8.7 0.43 1.41e-16 Prudent dietary pattern; LIHC cis rs3741404 0.825 rs2515241 chr11:63975331 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.93 16.26 0.66 1.93e-44 Platelet count; LIHC cis rs2839186 0.814 rs2839167 chr21:47661587 A/G cg13012494 chr21:47604986 C21orf56 0.41 6.34 0.32 7.23e-10 Testicular germ cell tumor; LIHC cis rs8017423 0.967 rs1005788 chr14:90692747 C/T cg14092571 chr14:90743983 NA -0.36 -5.72 -0.3 2.29e-8 Mortality in heart failure; LIHC cis rs7772486 0.790 rs1062068 chr6:146207465 A/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.09 -0.31 2.97e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2282802 0.685 rs7715538 chr5:139665181 T/C cg26211634 chr5:139558579 C5orf32 0.38 5.85 0.3 1.17e-8 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.596 rs2867301 chr1:150653795 C/T cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Tonsillectomy; LIHC cis rs1801251 1.000 rs9653383 chr2:233670380 A/C cg08000102 chr2:233561755 GIGYF2 -0.76 -11.27 -0.52 2.9e-25 Coronary artery disease; LIHC cis rs4718428 0.705 rs28648401 chr7:66367132 T/C cg18252515 chr7:66147081 NA -0.69 -9.54 -0.46 2.69e-19 Corneal structure; LIHC cis rs3784262 1.000 rs4646627 chr15:58255305 A/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.38 -0.33 5.65e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs597539 0.652 rs592697 chr11:68650064 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.96 0.51 3.7e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs600806 0.854 rs10745353 chr1:109877506 A/G cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.14 -0.32 2.3e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg24209194 chr3:40518798 ZNF619 0.62 9.26 0.45 2.27e-18 Renal cell carcinoma; LIHC cis rs17253792 0.822 rs75936910 chr14:56149351 T/C cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC cis rs963731 0.649 rs2123881 chr2:39247742 G/A cg04010122 chr2:39346883 SOS1 -0.68 -5.84 -0.3 1.19e-8 Corticobasal degeneration; LIHC cis rs748404 0.631 rs560191 chr15:43767774 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.88 0.39 4.43e-14 Lung cancer; LIHC cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg03264133 chr6:25882463 NA -0.43 -6.62 -0.34 1.36e-10 Height; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg21400344 chr1:25870172 LDLRAP1 -0.51 -6.38 -0.33 5.6e-10 Hepatitis; LIHC cis rs870825 0.616 rs7658186 chr4:185622509 T/C cg04058563 chr4:185651563 MLF1IP 0.77 7.67 0.38 1.81e-13 Blood protein levels; LIHC cis rs8078723 1.000 rs4795415 chr17:38157995 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.22 -0.45 3.13e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs317689 0.658 rs479971 chr12:69672471 A/G cg19645103 chr12:69753606 YEATS4 -0.45 -6.02 -0.31 4.56e-9 Response to diuretic therapy; LIHC cis rs2288912 0.838 rs2239375 chr19:45459851 T/C cg09555818 chr19:45449301 APOC2 0.19 5.77 0.3 1.81e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7116495 0.609 rs2276396 chr11:71823905 G/C cg26138937 chr11:71823887 C11orf51 1.31 10.37 0.49 4.19e-22 Severe influenza A (H1N1) infection; LIHC cis rs311392 0.966 rs454975 chr8:55087514 T/C cg20636351 chr8:55087400 NA -0.4 -8.06 -0.4 1.31e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs62458065 0.640 rs6950077 chr7:32502895 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.6 6.03 0.31 4.21e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs9916302 0.706 rs9909304 chr17:37500508 G/T cg07936489 chr17:37558343 FBXL20 0.85 12.19 0.55 1.26e-28 Glomerular filtration rate (creatinine); LIHC cis rs4969178 1.000 rs4969178 chr17:76388202 C/T cg20026190 chr17:76395443 PGS1 -0.39 -6.23 -0.32 1.37e-9 HDL cholesterol levels; LIHC cis rs10504229 0.593 rs16921626 chr8:58040359 C/T cg02290350 chr8:58132656 NA 0.33 7.25 0.36 2.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs344364 0.602 rs12719796 chr16:1921197 A/G cg00564555 chr16:1970112 NA 0.26 6.08 0.31 3.18e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs12594515 1.000 rs8039622 chr15:45986431 A/G cg06207120 chr15:45996521 NA 0.34 6.62 0.34 1.39e-10 Waist circumference;Weight; LIHC cis rs317689 0.690 rs10878947 chr12:69642683 A/T cg19645103 chr12:69753606 YEATS4 -0.44 -5.77 -0.3 1.76e-8 Response to diuretic therapy; LIHC cis rs1348850 0.609 rs1348851 chr2:178418677 C/T cg27490568 chr2:178487706 NA -0.9 -10.02 -0.48 6.78e-21 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7238033 0.624 rs9946832 chr18:43312790 A/G cg20610511 chr18:43302872 SLC14A1 0.37 6.24 0.32 1.31e-9 Bladder cancer; LIHC trans rs4714291 0.963 rs4714293 chr6:40009566 T/C cg02267698 chr19:7991119 CTXN1 0.38 6.15 0.32 2.12e-9 Strep throat; LIHC cis rs3768617 0.868 rs2296299 chr1:183104013 G/A ch.1.3577855R chr1:183094577 LAMC1 0.52 8.43 0.41 9.75e-16 Fuchs's corneal dystrophy; LIHC cis rs7191439 0.728 rs8043637 chr16:88781125 T/C cg02389323 chr16:88786976 FAM38A 0.77 7.12 0.36 6.48e-12 Plateletcrit; LIHC cis rs10838687 0.736 rs7933246 chr11:47262648 G/C cg25783544 chr11:47291846 MADD 0.46 5.93 0.31 7.57e-9 Proinsulin levels; LIHC cis rs796364 0.806 rs6435041 chr2:200867144 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 7.46 0.37 7e-13 Schizophrenia; LIHC cis rs1577917 0.883 rs1337854 chr6:86724015 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.41 7.37 0.37 1.26e-12 Response to antipsychotic treatment; LIHC cis rs1800469 1.000 rs1982072 chr19:41864509 T/A cg09537434 chr19:41945824 ATP5SL -0.72 -9.99 -0.48 8.35e-21 Colorectal cancer; LIHC cis rs9783347 0.890 rs11024634 chr11:18392074 G/A cg15585147 chr11:18324498 HPS5 0.42 6.5 0.33 2.78e-10 Pancreatic cancer; LIHC cis rs9921222 0.521 rs9935268 chr16:381562 G/C cg00101154 chr16:420108 MRPL28 -0.56 -7.89 -0.39 4.15e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs7131987 0.675 rs3847678 chr12:29551560 A/C cg14222432 chr12:29376421 FAR2 -0.3 -5.85 -0.3 1.17e-8 QT interval; LIHC cis rs4332037 0.539 rs868754 chr7:2033780 G/C cg23422044 chr7:1970798 MAD1L1 -0.62 -6.94 -0.35 1.92e-11 Bipolar disorder; LIHC cis rs832540 0.669 rs173764 chr5:56198920 C/T cg24531977 chr5:56204891 C5orf35 -0.5 -7.18 -0.36 4.28e-12 Coronary artery disease; LIHC cis rs2354432 0.556 rs66501488 chr1:146853992 T/C cg25205988 chr1:146714368 CHD1L -0.84 -9.5 -0.46 3.87e-19 Mitochondrial DNA levels; LIHC cis rs3820068 0.705 rs4646103 chr1:15819827 T/A cg17385448 chr1:15911702 AGMAT 0.37 6.3 0.32 9.39e-10 Systolic blood pressure; LIHC cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg12292205 chr6:26970375 C6orf41 -0.41 -7.06 -0.36 9.22e-12 Schizophrenia; LIHC cis rs10089 1.000 rs10478796 chr5:127436187 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.81 0.35 4.32e-11 Ileal carcinoids; LIHC cis rs1023500 0.573 rs133380 chr22:42468910 C/T cg04733989 chr22:42467013 NAGA 0.42 6.06 0.31 3.69e-9 Schizophrenia; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg10360139 chr7:1886902 MAD1L1 -0.43 -6.59 -0.34 1.63e-10 Bipolar disorder and schizophrenia; LIHC cis rs9457247 0.602 rs9457262 chr6:167473685 A/G cg07741184 chr6:167504864 NA 0.35 8.11 0.4 9.08e-15 Crohn's disease; LIHC cis rs986417 1.000 rs10142455 chr14:60980963 G/A cg27398547 chr14:60952738 C14orf39 0.76 8.46 0.42 8.18e-16 Gut microbiota (bacterial taxa); LIHC cis rs1008375 1.000 rs6449323 chr4:17683916 A/T cg16339924 chr4:17578868 LAP3 0.47 6.34 0.32 7.07e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs798554 0.757 rs1182178 chr7:2873763 G/A cg19717773 chr7:2847554 GNA12 -0.42 -6.49 -0.33 3e-10 Height; LIHC cis rs875971 0.830 rs6950137 chr7:65976610 G/A cg11764359 chr7:65958608 NA 0.85 15.3 0.64 1.23e-40 Aortic root size; LIHC cis rs6546550 0.901 rs13015457 chr2:70125763 G/T cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC cis rs7106204 0.748 rs7946633 chr11:24237411 C/T ch.11.24196551F chr11:24239977 NA 0.82 11.63 0.53 1.46e-26 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg25894440 chr7:65020034 NA -0.54 -6.22 -0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs9916302 0.904 rs57399933 chr17:37551189 A/G cg07936489 chr17:37558343 FBXL20 0.84 13.48 0.59 1.65e-33 Glomerular filtration rate (creatinine); LIHC cis rs4517514 0.509 rs11018870 chr11:89871409 T/G cg05041596 chr11:89867385 NAALAD2 0.42 6.95 0.35 1.88e-11 Trans fatty acid levels; LIHC cis rs2749592 0.550 rs12255038 chr10:37869332 T/C cg25427524 chr10:38739819 LOC399744 0.56 10.16 0.48 2.36e-21 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs11098499 0.954 rs17005535 chr4:120411562 C/T cg25214090 chr10:38739885 LOC399744 0.58 9.52 0.46 3.25e-19 Corneal astigmatism; LIHC cis rs769267 0.965 rs2916068 chr19:19516433 A/G cg03709012 chr19:19516395 GATAD2A 1.0 17.58 0.69 1.01e-49 Tonsillectomy; LIHC cis rs2153535 0.580 rs718502 chr6:8527400 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.52 0.53 3.67e-26 Motion sickness; LIHC cis rs9993613 0.934 rs4694493 chr4:73437261 C/T cg15102770 chr4:73434591 ADAMTS3 0.39 6.26 0.32 1.17e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs7312933 0.618 rs7315968 chr12:42637086 G/A cg01256987 chr12:42539512 GXYLT1 -0.39 -6.56 -0.33 1.97e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg03264133 chr6:25882463 NA -0.69 -8.69 -0.43 1.54e-16 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.610 rs6993531 chr8:58147283 A/G cg21448741 chr8:58168803 NA 0.31 5.87 0.3 1.02e-8 Developmental language disorder (linguistic errors); LIHC cis rs7904368 0.806 rs3858182 chr10:16855094 C/T cg23933602 chr10:16859644 RSU1 0.59 5.81 0.3 1.42e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs6754311 0.731 rs12615624 chr2:136721603 A/G cg07169764 chr2:136633963 MCM6 0.69 10.67 0.5 3.87e-23 Mosquito bite size; LIHC cis rs546131 0.642 rs34999475 chr11:34829848 G/A cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.52 -0.33 2.52e-10 Lung disease severity in cystic fibrosis; LIHC cis rs9911578 0.835 rs9788975 chr17:56460800 G/A cg12560992 chr17:57184187 TRIM37 -0.9 -14.87 -0.63 6.48e-39 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg26338869 chr17:61819248 STRADA -0.48 -6.43 -0.33 4.22e-10 Height; LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg21003380 chr1:156261207 TMEM79 0.37 5.98 0.31 5.69e-9 Tonsillectomy; LIHC cis rs11252926 0.537 rs6560836 chr10:444997 C/T cg16346588 chr10:242978 ZMYND11 0.38 5.87 0.3 1.02e-8 Psychosis in Alzheimer's disease; LIHC cis rs3862030 0.720 rs3740414 chr10:104232809 T/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.27 -0.37 2.42e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs11148252 0.532 rs9536262 chr13:53303074 A/C cg00495681 chr13:53174319 NA -0.73 -12.29 -0.55 5.25e-29 Lewy body disease; LIHC cis rs2239547 0.603 rs17304995 chr3:53070755 A/G cg11645453 chr3:52864694 ITIH4 0.26 6.4 0.33 5.16e-10 Schizophrenia; LIHC cis rs9948 1.000 rs9948 chr2:97500800 C/G cg01990225 chr2:97406019 LMAN2L 0.58 5.95 0.31 6.59e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs875971 0.862 rs908915 chr7:65614651 G/T cg18252515 chr7:66147081 NA 0.43 5.88 0.3 9.8e-9 Aortic root size; LIHC cis rs12079745 0.793 rs12067139 chr1:169254507 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -7.4 -0.37 1.04e-12 QT interval; LIHC cis rs2282802 0.685 rs6867870 chr5:139641896 C/A cg26211634 chr5:139558579 C5orf32 0.39 5.97 0.31 6.1e-9 Intelligence (multi-trait analysis); LIHC cis rs655641 0.871 rs603615 chr11:85709559 G/A cg09030501 chr11:85779252 PICALM -0.53 -6.44 -0.33 4.11e-10 Platelet count; LIHC trans rs1814175 0.669 rs11040455 chr11:49669829 G/C cg15704280 chr7:45808275 SEPT13 -0.63 -11.02 -0.51 2.19e-24 Height; LIHC cis rs798554 0.757 rs1182181 chr7:2873247 C/G cg19717773 chr7:2847554 GNA12 -0.42 -6.41 -0.33 4.88e-10 Height; LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.29 0.32 9.44e-10 Renal cell carcinoma; LIHC cis rs16912285 0.688 rs10834313 chr11:24348447 G/C ch.11.24196551F chr11:24239977 NA 0.67 7.52 0.38 4.96e-13 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01442903 chr1:55181833 TTC4 0.38 6.12 0.31 2.59e-9 Calcium levels; LIHC cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg24101359 chr6:42928495 GNMT 0.43 5.83 0.3 1.3e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1385374 0.858 rs11059928 chr12:129296103 A/T cg09035930 chr12:129282057 SLC15A4 -0.5 -6.02 -0.31 4.44e-9 Systemic lupus erythematosus; LIHC cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.34 -0.32 7.27e-10 Bipolar disorder and schizophrenia; LIHC cis rs6952809 0.532 rs10272548 chr7:2439467 G/A cg23289794 chr7:2394357 EIF3B -0.67 -6.59 -0.34 1.71e-10 Multiple sclerosis; LIHC cis rs2439831 0.850 rs28718261 chr15:44043793 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.47 0.42 7.46e-16 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22335246 chr12:120763591 PLA2G1B 0.38 6.21 0.32 1.58e-9 Pancreatic cancer; LIHC cis rs7674212 0.541 rs2623064 chr4:104030792 C/A cg16532752 chr4:104119610 CENPE -0.44 -6.89 -0.35 2.67e-11 Type 2 diabetes; LIHC cis rs7917772 0.636 rs7088981 chr10:104520423 T/C cg22532475 chr10:104410764 TRIM8 0.37 6.39 0.33 5.3e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs360798 0.512 rs2058566 chr2:63179076 C/T cg17519650 chr2:63277830 OTX1 0.58 8.68 0.42 1.7e-16 Coronary artery disease; LIHC cis rs909341 0.909 rs2257440 chr20:62328267 C/T cg03999872 chr20:62272968 STMN3 -0.46 -6.78 -0.34 5.22e-11 Atopic dermatitis; LIHC cis rs798554 0.797 rs798491 chr7:2800521 A/G cg19717773 chr7:2847554 GNA12 -0.41 -6.65 -0.34 1.18e-10 Height; LIHC cis rs2191566 0.960 rs6509133 chr19:44522913 A/G cg20607764 chr19:44506953 ZNF230 0.39 6.37 0.33 6.01e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs6565180 1.000 rs12930787 chr16:30381303 C/G cg17640201 chr16:30407289 ZNF48 -0.77 -12.84 -0.57 4.68e-31 Tonsillectomy; LIHC cis rs11583043 1.000 rs6660290 chr1:101483512 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.59 -7.9 -0.39 3.72e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4819052 0.918 rs34886433 chr21:46680538 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.63 7.9 0.39 3.85e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg08168689 chr14:76455272 C14orf179 0.42 6.22 0.32 1.43e-9 Bilirubin levels; LIHC cis rs2439831 0.618 rs999026 chr15:43690215 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.85 15.31 0.64 1.18e-40 Lung cancer in ever smokers; LIHC cis rs10857712 0.754 rs2297032 chr10:135234580 C/T cg01444801 chr10:135216882 MTG1 -0.63 -9.33 -0.45 1.37e-18 Systemic lupus erythematosus; LIHC cis rs344364 0.511 rs12596510 chr16:1949480 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs600806 0.778 rs518697 chr1:110014778 G/A cg08911820 chr1:110026001 ATXN7L2 -0.58 -7.38 -0.37 1.18e-12 Intelligence (multi-trait analysis); LIHC cis rs11971779 0.715 rs10265 chr7:139026152 T/G cg07862535 chr7:139043722 LUC7L2 0.58 10.03 0.48 6.38e-21 Diisocyanate-induced asthma; LIHC cis rs7100689 0.622 rs1417221 chr10:82100428 G/A cg00277334 chr10:82204260 NA -0.56 -7.08 -0.36 8.39e-12 Post bronchodilator FEV1; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20604317 chr20:4129314 SMOX 0.46 6.37 0.33 6.2e-10 Lung function (FEV1/FVC); LIHC cis rs7534824 0.543 rs72734254 chr1:101382039 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.53 0.38 4.55e-13 Refractive astigmatism; LIHC cis rs4819052 1.000 rs28628220 chr21:46663741 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 9.81 0.47 3.45e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11098499 0.754 rs10212714 chr4:120254302 T/C cg09307838 chr4:120376055 NA 0.7 10.88 0.51 6.94e-24 Corneal astigmatism; LIHC cis rs801193 0.569 rs7782587 chr7:66166472 C/T cg18252515 chr7:66147081 NA -0.47 -6.86 -0.35 3.26e-11 Aortic root size; LIHC cis rs9513627 0.915 rs4539436 chr13:100122802 C/G cg25919922 chr13:100150906 NA -0.79 -6.95 -0.35 1.86e-11 Obesity-related traits; LIHC cis rs6964587 0.839 rs62466159 chr7:91450507 A/G cg17063962 chr7:91808500 NA 0.96 17.6 0.69 8.27e-50 Breast cancer; LIHC cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC cis rs9814567 0.964 rs6805388 chr3:134173534 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.55 -9.94 -0.47 1.28e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg11764359 chr7:65958608 NA -0.58 -6.03 -0.31 4.27e-9 Diabetic kidney disease; LIHC cis rs2933343 0.700 rs1683779 chr3:128642048 A/G cg25356066 chr3:128598488 ACAD9 0.51 7.08 0.36 8.23e-12 IgG glycosylation; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.71 12.34 0.55 3.57e-29 Prudent dietary pattern; LIHC cis rs344364 0.511 rs2982452 chr16:1949511 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg12756686 chr19:29218302 NA 0.43 6.44 0.33 4.1e-10 Methadone dose in opioid dependence; LIHC cis rs425277 1.000 rs436045 chr1:2071556 A/G cg24578937 chr1:2090814 PRKCZ -0.49 -8.6 -0.42 2.91e-16 Height; LIHC cis rs11122272 0.735 rs2066140 chr1:231504311 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.69 -0.5 3.28e-23 Hemoglobin concentration; LIHC cis rs881375 0.967 rs1860823 chr9:123659304 T/C cg14580859 chr9:123691850 NA 0.38 6.47 0.33 3.3e-10 Rheumatoid arthritis; LIHC cis rs992157 0.866 rs2292554 chr2:219146868 T/C cg00012203 chr2:219082015 ARPC2 -0.82 -13.06 -0.58 6.88e-32 Colorectal cancer; LIHC cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg03452623 chr4:187889614 NA -0.32 -8.31 -0.41 2.33e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs734999 0.545 rs6666788 chr1:2567500 A/G cg18854424 chr1:2615690 NA -0.33 -7.36 -0.37 1.39e-12 Ulcerative colitis; LIHC cis rs1200821 0.535 rs1938417 chr10:37687520 A/C cg00409905 chr10:38381863 ZNF37A 0.38 5.82 0.3 1.36e-8 Hemostatic factors and hematological phenotypes; LIHC cis rs9467773 1.000 rs6925895 chr6:26572165 G/T cg11502198 chr6:26597334 ABT1 0.47 6.84 0.35 3.7e-11 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -11.97 -0.54 8.07e-28 Alzheimer's disease; LIHC cis rs77216612 0.835 rs10845621 chr12:12887977 C/T cg24098013 chr12:12878779 APOLD1 0.56 7.94 0.39 2.89e-14 Lymphocyte counts; LIHC cis rs7572733 0.534 rs770662 chr2:198729283 T/C cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs11671005 0.737 rs11673101 chr19:58995053 G/C cg25952890 chr19:58913133 NA 0.73 7.45 0.37 7.64e-13 Mean platelet volume; LIHC cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.09 0.44 8.21e-18 Platelet count; LIHC cis rs1552244 0.882 rs13089863 chr3:10032259 G/T cg02579736 chr3:10068473 FANCD2;CIDECP -0.72 -9.55 -0.46 2.67e-19 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07030052 chr1:162531143 UAP1 -0.41 -6.04 -0.31 4.03e-9 Cognitive function; LIHC cis rs7487075 0.780 rs2279559 chr12:46767175 A/C cg15584813 chr12:47219626 SLC38A4 0.33 5.84 0.3 1.24e-8 Itch intensity from mosquito bite; LIHC cis rs10751667 0.666 rs7396677 chr11:958878 C/T cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.02e-12 Alzheimer's disease (late onset); LIHC cis rs7635838 0.718 rs2606736 chr3:11400249 C/T cg00170343 chr3:11313890 ATG7 0.48 7.71 0.38 1.42e-13 HDL cholesterol; LIHC trans rs60843830 1.000 rs2290911 chr2:224919 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.67 9.55 0.46 2.59e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs782590 0.902 rs782601 chr2:55848244 T/C cg18811423 chr2:55921094 PNPT1 0.95 14.93 0.63 3.78e-39 Metabolic syndrome; LIHC cis rs11098499 0.908 rs9995234 chr4:120321827 A/G cg09307838 chr4:120376055 NA 0.77 11.85 0.54 2.3e-27 Corneal astigmatism; LIHC cis rs9858542 0.953 rs67216675 chr3:49493151 G/T cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1997103 1.000 rs6945937 chr7:55407140 C/T cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg00475322 chr7:917719 C7orf20 0.42 7.07 0.36 8.66e-12 Perceived unattractiveness to mosquitoes; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg11257324 chr6:150232174 NA 0.37 6.16 0.32 1.99e-9 Lung cancer; LIHC cis rs66887589 0.934 rs41464847 chr4:120532401 A/G cg09307838 chr4:120376055 NA -0.45 -6.75 -0.34 6.35e-11 Diastolic blood pressure; LIHC cis rs7666738 0.606 rs4577589 chr4:99087858 A/G cg05340658 chr4:99064831 C4orf37 0.65 11.68 0.53 9.06e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs875971 0.964 rs11765965 chr7:65842221 A/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs909002 0.800 rs968335 chr1:32085776 G/A cg13919466 chr1:32135498 COL16A1 -0.34 -6.34 -0.32 7.19e-10 Intelligence (multi-trait analysis); LIHC cis rs7618501 0.633 rs4688689 chr3:50035542 C/T cg24110177 chr3:50126178 RBM5 -0.45 -7.23 -0.36 3.26e-12 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.623 rs73271872 chr17:29152228 C/G cg14067834 chr17:29058358 SUZ12P 0.69 6.69 0.34 9.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7927592 0.956 rs10896348 chr11:68357368 T/C cg16797656 chr11:68205561 LRP5 0.52 8.36 0.41 1.58e-15 Total body bone mineral density; LIHC cis rs921968 0.619 rs1554623 chr2:219606177 C/T cg02985541 chr2:219472218 PLCD4 -0.36 -6.34 -0.32 7.29e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs244293 0.965 rs2628324 chr17:53202977 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.63 -0.38 2.39e-13 Menarche (age at onset); LIHC cis rs4803468 0.763 rs17318596 chr19:41937095 A/G cg09537434 chr19:41945824 ATP5SL -1.04 -22.88 -0.78 5.95e-71 Height; LIHC cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg25894440 chr7:65020034 NA -0.51 -5.87 -0.3 1.01e-8 Diabetic kidney disease; LIHC trans rs4906332 1.000 rs12892062 chr14:103883512 A/G cg17675199 chr6:35436792 RPL10A 0.31 6.08 0.31 3.13e-9 Coronary artery disease; LIHC cis rs11122272 0.735 rs2474625 chr1:231519331 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs6430585 0.702 rs2015532 chr2:136555525 G/T cg07169764 chr2:136633963 MCM6 -1.06 -13.4 -0.59 3.34e-33 Corneal structure; LIHC trans rs4927850 1.000 rs7630875 chr3:195753766 A/G cg21051086 chr3:73046214 PPP4R2 -0.38 -6.05 -0.31 3.72e-9 Pancreatic cancer; LIHC cis rs8180040 0.726 rs7625070 chr3:47095518 A/G cg27129171 chr3:47204927 SETD2 0.69 12.38 0.56 2.55e-29 Colorectal cancer; LIHC cis rs1008375 1.000 rs6846238 chr4:17629939 A/G cg02297831 chr4:17616191 MED28 0.47 7.33 0.37 1.64e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12365397 1.000 rs10838072 chr11:43227569 G/A cg16667275 chr11:43333495 API5 0.44 6.05 0.31 3.91e-9 Migraine; LIHC cis rs2153535 0.580 rs6926759 chr6:8456176 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.51 0.42 5.55e-16 Motion sickness; LIHC cis rs1865760 0.534 rs2032444 chr6:26046744 T/G cg16482183 chr6:26056742 HIST1H1C 0.46 6.33 0.32 7.53e-10 Height; LIHC cis rs7769051 1.000 rs58832890 chr6:133127139 C/T cg07930552 chr6:133119739 C6orf192 0.66 6.19 0.32 1.71e-9 Type 2 diabetes nephropathy; LIHC cis rs716804 0.740 rs7938543 chr11:10229851 G/A cg01453529 chr11:10209919 SBF2 0.3 5.9 0.3 8.58e-9 Neuroticism; LIHC cis rs9916302 0.904 rs612194 chr17:37442707 T/A cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC cis rs12497850 0.897 rs7373778 chr3:48836392 C/G cg07636037 chr3:49044803 WDR6 0.93 16.69 0.67 3.72e-46 Parkinson's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg10100767 chr14:105246561 AKT1 0.42 6.25 0.32 1.25e-9 Longevity; LIHC cis rs17685 0.753 rs1104878 chr7:75685593 G/T cg16684958 chr7:75615977 POR 0.51 8.61 0.42 2.78e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6912958 0.559 rs395358 chr6:88057924 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.36 0.37 1.39e-12 Monocyte percentage of white cells; LIHC trans rs3942852 0.696 rs4597030 chr11:48176573 G/A cg03929089 chr4:120376271 NA -0.56 -7.62 -0.38 2.6e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs17685 0.753 rs10262501 chr7:75668172 G/A cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.53 -0.71 1.41e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12579753 0.956 rs7965168 chr12:82184467 C/A cg07988820 chr12:82153109 PPFIA2 -0.49 -6.04 -0.31 4.12e-9 Resting heart rate; LIHC cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC trans rs5756813 0.754 rs762982 chr22:38144235 A/G cg19894588 chr14:64061835 NA 0.6 8.03 0.4 1.56e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg03517284 chr6:25882590 NA -0.67 -8.63 -0.42 2.33e-16 Intelligence (multi-trait analysis); LIHC cis rs7116495 0.609 rs10736783 chr11:71654143 G/A cg10381502 chr11:71823885 C11orf51 -1.0 -8.24 -0.41 3.84e-15 Severe influenza A (H1N1) infection; LIHC cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg08392591 chr16:89556376 ANKRD11 0.49 7.77 0.39 9.5e-14 Multiple myeloma (IgH translocation); LIHC cis rs4253772 0.591 rs6008362 chr22:46652737 G/A cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.72 6.51 0.33 2.69e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs7937682 0.632 rs4936800 chr11:111734097 T/A cg09085632 chr11:111637200 PPP2R1B 0.96 13.88 0.6 4.81e-35 Primary sclerosing cholangitis; LIHC cis rs4660306 0.961 rs4660862 chr1:45955056 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC -0.64 -7.61 -0.38 2.7e-13 Homocysteine levels; LIHC cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg11062466 chr8:58055876 NA 0.47 6.6 0.34 1.59e-10 Developmental language disorder (linguistic errors); LIHC cis rs11098699 0.821 rs7665617 chr4:124201196 C/G cg09941581 chr4:124220074 SPATA5 0.33 6.61 0.34 1.5e-10 Mosquito bite size; LIHC cis rs80282103 0.867 rs3793781 chr10:1081293 G/T cg20335179 chr10:1068567 C10orf110;IDI2 -0.56 -6.05 -0.31 3.91e-9 Glomerular filtration rate (creatinine); LIHC cis rs4474465 0.646 rs7927503 chr11:78280606 G/T cg27205649 chr11:78285834 NARS2 0.5 7.88 0.39 4.27e-14 Alzheimer's disease (survival time); LIHC cis rs5417 0.788 rs2654185 chr17:7183362 G/T cg14660024 chr17:7154518 C17orf81;DULLARD -0.39 -7.57 -0.38 3.56e-13 Diastolic blood pressure; LIHC cis rs4586057 0.514 rs7101301 chr10:92649923 G/A cg14313238 chr10:92632228 RPP30 0.36 6.04 0.31 4.03e-9 Economic and political preferences (time); LIHC cis rs2834256 0.961 rs9981693 chr21:35042550 A/G cg14850771 chr21:34775459 IFNGR2 0.39 6.17 0.32 1.98e-9 Red cell distribution width; LIHC cis rs2016586 0.895 rs5750162 chr22:36114551 T/C cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 7.96e-10 Body mass index; LIHC cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg04267008 chr7:1944627 MAD1L1 -0.65 -10.39 -0.49 3.62e-22 Bipolar disorder and schizophrenia; LIHC cis rs2288073 1.000 rs6708328 chr2:24412413 A/G cg06627628 chr2:24431161 ITSN2 -0.61 -8.22 -0.41 4.13e-15 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs595982 0.702 rs609985 chr19:49370648 A/G cg21252483 chr19:49399788 TULP2 -0.45 -7.43 -0.37 8.95e-13 Red cell distribution width; LIHC cis rs7572733 0.534 rs1401095 chr2:198779867 C/T cg03934865 chr2:198174659 NA -0.46 -6.7 -0.34 8.85e-11 Dermatomyositis; LIHC cis rs9733 0.519 rs1336899 chr1:150678910 T/C cg17724175 chr1:150552817 MCL1 0.49 9.89 0.47 1.92e-20 Tonsillectomy; LIHC cis rs4803468 1.000 rs878083 chr19:41897688 G/A cg14132834 chr19:41945861 ATP5SL -0.42 -6.18 -0.32 1.83e-9 Height; LIHC cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.68 0.34 9.67e-11 Bipolar disorder; LIHC cis rs4819052 1.000 rs2838830 chr21:46664227 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 9.75 0.47 5.8e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11098499 0.954 rs6834796 chr4:120414693 A/C cg09307838 chr4:120376055 NA 0.77 12.25 0.55 7.23e-29 Corneal astigmatism; LIHC cis rs6762477 0.748 rs3755831 chr3:50228767 G/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.47 -7.27 -0.37 2.4e-12 Menarche (age at onset); LIHC cis rs17428076 0.836 rs57775770 chr2:172687731 T/C cg13550731 chr2:172543902 DYNC1I2 0.38 6.3 0.32 9.4e-10 Myopia; LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg14671364 chr1:107599128 PRMT6 0.52 7.83 0.39 6.25e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11630290 0.592 rs12324668 chr15:64161786 A/T cg12036633 chr15:63758958 NA 0.61 6.49 0.33 2.94e-10 Iris characteristics; LIHC cis rs6723226 0.650 rs6729952 chr2:32764922 T/C cg02381751 chr2:32503542 YIPF4 0.63 9.58 0.46 2.01e-19 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg07424592 chr7:64974309 NA 0.8 9.39 0.45 8.41e-19 Diabetic kidney disease; LIHC cis rs12291225 0.645 rs3763950 chr11:14278049 T/A cg05501817 chr11:14380813 RRAS2 -0.42 -5.76 -0.3 1.84e-8 Sense of smell; LIHC cis rs1707322 0.686 rs2991986 chr1:46081282 A/G cg24296786 chr1:45957014 TESK2 0.41 5.99 0.31 5.42e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10751667 0.560 rs10902265 chr11:1003642 G/A ch.11.42038R chr11:967971 AP2A2 0.6 11.19 0.52 5.7e-25 Alzheimer's disease (late onset); LIHC cis rs72781680 1.000 rs12616250 chr2:24211550 T/C cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs11690935 0.527 rs7586556 chr2:172901887 G/C cg13550731 chr2:172543902 DYNC1I2 0.47 6.81 0.35 4.36e-11 Schizophrenia; LIHC cis rs1577917 0.958 rs12213343 chr6:86443019 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.44 -0.42 9.26e-16 Response to antipsychotic treatment; LIHC cis rs10847980 0.590 rs2292131 chr12:123332354 C/T cg07706471 chr12:123319906 HIP1R 0.77 8.68 0.42 1.66e-16 Adiponectin levels; LIHC cis rs7089973 0.604 rs17095662 chr10:116596071 A/C cg03647239 chr10:116582469 FAM160B1 0.46 6.73 0.34 7.16e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs3106136 0.546 rs2632417 chr4:95137542 G/C cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.3 -0.45 1.73e-18 Capecitabine sensitivity; LIHC cis rs523522 0.962 rs603574 chr12:120998443 A/G cg27279351 chr12:120934652 DYNLL1 0.67 12.13 0.55 2.12e-28 High light scatter reticulocyte count; LIHC trans rs6928977 0.660 rs12203875 chr6:135860414 C/T cg13374867 chr5:43514950 C5orf34 -0.46 -6.56 -0.33 2e-10 Nodular sclerosis Hodgkin lymphoma;Hodgkin's lymphoma; LIHC cis rs921968 0.643 rs563268 chr2:219372912 T/G cg02985541 chr2:219472218 PLCD4 0.46 8.73 0.43 1.18e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs4820539 1.000 rs5759598 chr22:23480962 T/G cg21100191 chr22:23484243 RTDR1 0.87 15.7 0.65 3.37e-42 Bone mineral density; LIHC cis rs6973256 0.605 rs7794168 chr7:133357606 T/C cg10665199 chr7:133106180 EXOC4 0.35 5.99 0.31 5.42e-9 Intelligence (multi-trait analysis); LIHC trans rs911555 0.755 rs8018400 chr14:103901085 A/G cg17675199 chr6:35436792 RPL10A -0.44 -9.16 -0.44 5.05e-18 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.855 rs11253459 chr10:886402 C/T cg20503657 chr10:835505 NA 1.02 12.21 0.55 1.02e-28 Eosinophil percentage of granulocytes; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs7727544 0.735 rs2631370 chr5:131703776 T/C cg24060327 chr5:131705240 SLC22A5 0.58 8.32 0.41 2.13e-15 Blood metabolite levels; LIHC cis rs9733 0.519 rs7529194 chr1:150622620 A/T cg15448220 chr1:150897856 SETDB1 0.42 6.64 0.34 1.23e-10 Tonsillectomy; LIHC cis rs765787 0.530 rs11636410 chr15:45535913 A/C cg24006582 chr15:45444508 DUOX1 0.52 7.42 0.37 9.08e-13 Uric acid levels; LIHC cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg16262614 chr3:133464971 TF 0.28 6.4 0.33 5.03e-10 Iron status biomarkers; LIHC trans rs6531296 0.558 rs9968503 chr4:34266281 T/C cg03525467 chr1:160098048 ATP1A2 -0.44 -6.25 -0.32 1.23e-9 Thoracic-to-hip circumference ratio; LIHC cis rs1005277 0.579 rs1780139 chr10:38503018 C/T cg25427524 chr10:38739819 LOC399744 -0.75 -15.09 -0.63 8.6e-40 Extrinsic epigenetic age acceleration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13827970 chr14:55369959 GCH1 0.41 6.08 0.31 3.26e-9 Pancreatic cancer; LIHC cis rs2839186 1.000 rs2839186 chr21:47690068 C/T cg11766577 chr21:47581405 C21orf56 -0.4 -6.27 -0.32 1.1e-9 Testicular germ cell tumor; LIHC cis rs1185460 0.565 rs657685 chr11:118912982 G/C cg23280166 chr11:118938394 VPS11 -0.45 -6.13 -0.31 2.36e-9 Coronary artery disease; LIHC cis rs9549367 0.577 rs3024718 chr13:113813853 C/T cg00898013 chr13:113819073 PROZ 0.45 7.61 0.38 2.72e-13 Platelet distribution width; LIHC cis rs3749237 0.595 rs1464568 chr3:49458266 G/A cg07636037 chr3:49044803 WDR6 0.52 8.04 0.4 1.44e-14 Resting heart rate; LIHC cis rs3540 0.533 rs7495080 chr15:91056681 G/A cg22089800 chr15:90895588 ZNF774 -0.47 -6.96 -0.35 1.76e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs911119 0.818 rs56077567 chr20:23591087 T/C cg16589663 chr20:23618590 CST3 0.72 7.54 0.38 4.32e-13 Chronic kidney disease; LIHC cis rs1577917 0.771 rs2842613 chr6:86305702 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.57 10.94 0.51 4.38e-24 Response to antipsychotic treatment; LIHC cis rs4925386 0.959 rs4925385 chr20:60920624 A/G cg06026331 chr20:60912101 LAMA5 -0.52 -8.8 -0.43 7.1e-17 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7208859 0.573 rs8078656 chr17:29080971 A/T cg13385521 chr17:29058706 SUZ12P 0.82 8.04 0.4 1.48e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7903847 0.642 rs7074511 chr10:99140177 G/A cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.3e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs7208859 0.510 rs216402 chr17:28917126 A/T cg14067834 chr17:29058358 SUZ12P 0.68 6.66 0.34 1.12e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs72949976 0.934 rs1441172 chr2:214037703 C/T cg08319019 chr2:214017104 IKZF2 -0.53 -5.93 -0.31 7.55e-9 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs10857712 1.000 rs10857712 chr10:135225666 T/C cg17796960 chr10:135278976 LOC619207 -0.34 -5.73 -0.3 2.19e-8 Systemic lupus erythematosus; LIHC cis rs11098499 0.954 rs12508504 chr4:120410607 A/C cg09307838 chr4:120376055 NA 0.78 12.57 0.56 4.74e-30 Corneal astigmatism; LIHC cis rs7188697 0.922 rs37036 chr16:58553348 T/C cg02549819 chr16:58548995 SETD6 -0.49 -7.7 -0.38 1.45e-13 QT interval; LIHC cis rs611744 0.967 rs603889 chr8:109224232 C/T cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs17428076 0.874 rs72885529 chr2:172684032 C/T cg13550731 chr2:172543902 DYNC1I2 0.38 6.21 0.32 1.54e-9 Myopia; LIHC cis rs10416265 0.528 rs3786932 chr19:33620488 T/A cg17764715 chr19:33622953 WDR88 0.51 6.8 0.35 4.57e-11 Bone properties (heel); LIHC cis rs6665290 0.904 rs1045290 chr1:227178700 A/G cg10327440 chr1:227177885 CDC42BPA -1.19 -31.54 -0.86 3e-103 Myeloid white cell count; LIHC trans rs62103177 0.810 rs62103191 chr18:77628769 C/G cg05926928 chr17:57297772 GDPD1 1.1 11.26 0.52 3.23e-25 Opioid sensitivity; LIHC cis rs597539 0.731 rs664229 chr11:68624483 C/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.71 9.87 0.47 2.21e-20 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs11098699 0.821 rs11734868 chr4:124211544 A/G cg09941581 chr4:124220074 SPATA5 0.33 6.61 0.34 1.47e-10 Mosquito bite size; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg23782820 chr8:58130467 NA -0.33 -5.81 -0.3 1.41e-8 Developmental language disorder (linguistic errors); LIHC cis rs9918079 0.560 rs6414767 chr4:15655721 A/G cg21329975 chr4:15471214 CC2D2A -0.42 -6.33 -0.32 7.71e-10 Obesity-related traits; LIHC cis rs11792861 0.566 rs6477687 chr9:111837791 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.45 -6.61 -0.34 1.5e-10 Menarche (age at onset); LIHC trans rs459571 0.959 rs2520099 chr9:136918139 T/C cg09836344 chr4:1243392 C4orf42;CTBP1 -0.53 -8.11 -0.4 9.22e-15 Platelet distribution width; LIHC cis rs17685 0.753 rs12531559 chr7:75631697 C/T cg16489192 chr7:75678113 MDH2;STYXL1 0.36 5.97 0.31 5.92e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04371633 chr14:65381025 CHURC1 0.47 7.62 0.38 2.45e-13 Cognitive function; LIHC cis rs7223966 1.000 rs9747164 chr17:61864787 T/C cg05941027 chr17:61774174 LIMD2 0.37 7.66 0.38 1.97e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9916302 0.706 rs649180 chr17:37464959 A/C cg07936489 chr17:37558343 FBXL20 0.85 12.2 0.55 1.1e-28 Glomerular filtration rate (creatinine); LIHC cis rs8103278 1.000 rs8102876 chr19:46332842 C/T cg14061069 chr19:46274453 DMPK -0.56 -8.53 -0.42 4.64e-16 Coronary artery disease; LIHC cis rs7903847 0.642 rs10786339 chr10:99153076 A/G cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.53e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7264396 0.563 rs3827029 chr20:34332784 G/T cg04508476 chr20:34239394 CPNE1;RBM12 0.58 8.45 0.42 8.36e-16 Total cholesterol levels; LIHC cis rs8017423 0.935 rs10147186 chr14:90779879 G/C cg14092571 chr14:90743983 NA -0.42 -6.75 -0.34 6.36e-11 Mortality in heart failure; LIHC cis rs2070433 0.539 rs1008549 chr21:47959698 C/T cg12379764 chr21:47803548 PCNT 0.63 9.57 0.46 2.16e-19 Lymphocyte counts; LIHC cis rs7264396 0.676 rs58372200 chr20:34555445 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs875971 0.862 rs778724 chr7:65829291 T/C cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs1018836 0.923 rs7013893 chr8:91563137 G/A cg16814680 chr8:91681699 NA -0.6 -9.55 -0.46 2.61e-19 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs875971 0.577 rs35072105 chr7:65609817 A/G cg18876405 chr7:65276391 NA -0.47 -7.93 -0.39 3.24e-14 Aortic root size; LIHC cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg19318889 chr4:1322082 MAEA 0.47 6.59 0.34 1.71e-10 Obesity-related traits; LIHC cis rs7107174 1.000 rs2512533 chr11:77968674 A/C cg02023728 chr11:77925099 USP35 0.5 9.51 0.46 3.41e-19 Testicular germ cell tumor; LIHC cis rs2522056 1.000 rs2706395 chr5:131796803 A/T cg24060327 chr5:131705240 SLC22A5 0.53 7.16 0.36 4.87e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs11690935 0.655 rs17614941 chr2:172541378 A/G cg13550731 chr2:172543902 DYNC1I2 0.5 8.68 0.43 1.61e-16 Schizophrenia; LIHC cis rs1348850 0.914 rs4341974 chr2:178324879 A/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.13 0.58 3.64e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs34330 0.562 rs11055025 chr12:12866619 A/T cg04607235 chr12:12878440 APOLD1 -0.76 -9.5 -0.46 3.69e-19 Systemic lupus erythematosus; LIHC cis rs798554 0.757 rs1182178 chr7:2873763 G/A cg13628971 chr7:2884303 GNA12 0.53 7.38 0.37 1.22e-12 Height; LIHC cis rs5753618 0.561 rs737684 chr22:31659827 C/G cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs3008870 0.959 rs3008852 chr1:67383416 G/A cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.29e-8 Lymphocyte percentage of white cells; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg21747090 chr2:27597821 SNX17 -0.44 -6.71 -0.34 8.05e-11 Total body bone mineral density; LIHC cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg00750074 chr16:89608354 SPG7 -0.51 -8.13 -0.4 8.18e-15 Multiple myeloma (IgH translocation); LIHC trans rs11098499 0.604 rs17051352 chr4:120581427 G/A cg25214090 chr10:38739885 LOC399744 0.56 8.72 0.43 1.23e-16 Corneal astigmatism; LIHC cis rs6545883 0.860 rs777589 chr2:61425621 T/C cg15711740 chr2:61764176 XPO1 -0.43 -5.89 -0.3 9.47e-9 Tuberculosis; LIHC cis rs7020830 0.931 rs13293916 chr9:37136359 C/G cg14294708 chr9:37120828 ZCCHC7 1.2 27.54 0.83 8.49e-89 Schizophrenia; LIHC cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg04267008 chr7:1944627 MAD1L1 -0.59 -9.09 -0.44 8.37e-18 Bipolar disorder and schizophrenia; LIHC cis rs2668423 0.501 rs502121 chr19:1387299 T/C cg02639931 chr19:1387894 NDUFS7 -0.84 -14.71 -0.62 2.74e-38 Nonalcoholic fatty liver disease; LIHC cis rs919433 0.963 rs10153881 chr2:198171098 T/C cg10820045 chr2:198174542 NA -0.58 -9.71 -0.46 7.47e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.9 0.3 8.95e-9 Menopause (age at onset); LIHC cis rs4665809 0.618 rs7579199 chr2:26266496 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.68 -8.32 -0.41 2.11e-15 Gut microbiome composition (summer); LIHC cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg06634786 chr22:41940651 POLR3H 0.73 7.51 0.38 5.22e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs262150 0.574 rs2730272 chr7:158798622 G/C cg27247782 chr7:158767135 NA -0.31 -5.9 -0.3 8.58e-9 Facial morphology (factor 20); LIHC cis rs864643 0.947 rs704962 chr3:39557120 C/T cg05136238 chr3:39556330 MOBP -0.29 -5.72 -0.3 2.3e-8 Attention deficit hyperactivity disorder; LIHC trans rs4906332 1.000 rs3783398 chr14:103949378 C/T cg17675199 chr6:35436792 RPL10A -0.36 -7.1 -0.36 7.35e-12 Coronary artery disease; LIHC cis rs2239547 0.618 rs4687658 chr3:52860366 C/G cg11645453 chr3:52864694 ITIH4 0.34 8.83 0.43 5.49e-17 Schizophrenia; LIHC cis rs244293 0.765 rs7503269 chr17:53019712 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.46 -6.16 -0.32 2.05e-9 Menarche (age at onset); LIHC cis rs7923452 0.938 rs753173 chr10:30778738 T/C cg25182066 chr10:30743637 MAP3K8 0.69 9.77 0.47 4.87e-20 Itch intensity from mosquito bite; LIHC cis rs6665290 0.836 rs56029302 chr1:227203390 G/A cg10327440 chr1:227177885 CDC42BPA -1.14 -26.82 -0.82 4.04e-86 Myeloid white cell count; LIHC cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg17971929 chr21:40555470 PSMG1 -0.78 -9.39 -0.45 8.57e-19 Cognitive function; LIHC cis rs41271473 0.526 rs10916344 chr1:228737489 C/T cg10167378 chr1:228756711 NA 0.61 6.51 0.33 2.64e-10 Chronic lymphocytic leukemia; LIHC cis rs2361710 1.000 rs2361710 chr17:78111877 C/T cg09238746 chr17:78121135 EIF4A3 0.55 8.22 0.41 4.33e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; LIHC cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg12463550 chr7:65579703 CRCP -0.73 -7.64 -0.38 2.24e-13 Diabetic kidney disease; LIHC cis rs6952808 0.609 rs12699453 chr7:1953056 C/T cg21782813 chr7:2030301 MAD1L1 0.44 7.59 0.38 3.17e-13 Bipolar disorder and schizophrenia; LIHC cis rs11792861 0.816 rs2275637 chr9:111696043 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 9.2 0.45 3.75e-18 Menarche (age at onset); LIHC cis rs8017423 0.845 rs80167706 chr14:90727629 G/C cg04374321 chr14:90722782 PSMC1 0.78 15.15 0.63 4.85e-40 Mortality in heart failure; LIHC cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg08888203 chr3:10149979 C3orf24 0.52 6.26 0.32 1.14e-9 Alzheimer's disease; LIHC cis rs589448 0.967 rs634512 chr12:69754012 C/T cg14784868 chr12:69753453 YEATS4 0.99 23.08 0.78 1.05e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs2242116 0.592 rs2290545 chr3:46967040 C/T cg02527881 chr3:46936655 PTH1R -0.42 -8.02 -0.4 1.75e-14 Birth weight; LIHC cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24317988 chr10:33247433 ITGB1 0.43 6.26 0.32 1.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12464559 0.649 rs2030588 chr2:152668750 C/A cg01189475 chr2:152685088 ARL5A 0.61 7.25 0.36 2.82e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs897984 0.520 rs4889622 chr16:30870957 A/G cg02466173 chr16:30829666 NA 0.48 7.23 0.36 3.15e-12 Dementia with Lewy bodies; LIHC cis rs2404602 0.692 rs35999717 chr15:77193367 G/C cg23625390 chr15:77176239 SCAPER 0.35 5.74 0.3 2.06e-8 Blood metabolite levels; LIHC cis rs16958440 0.867 rs79078752 chr18:44667462 A/G cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs4891159 0.724 rs690639 chr18:74108957 C/T cg24786174 chr18:74118243 ZNF516 0.78 13.93 0.6 2.95e-35 Longevity; LIHC cis rs17376456 1.000 rs34854140 chr5:93538169 G/A cg25358565 chr5:93447407 FAM172A 1.08 9.74 0.47 6e-20 Diabetic retinopathy; LIHC cis rs1113500 0.814 rs893983 chr1:108630338 C/T cg06207961 chr1:108661230 NA -0.31 -5.84 -0.3 1.19e-8 Growth-regulated protein alpha levels; LIHC cis rs7208859 0.673 rs56146117 chr17:29153325 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.69 0.34 9.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6120849 0.754 rs6088678 chr20:33607551 A/G cg24642439 chr20:33292090 TP53INP2 -0.64 -7.08 -0.36 8.35e-12 Protein C levels; LIHC cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg22105103 chr4:187893119 NA 0.34 8.56 0.42 4e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs6815814 0.768 rs6835514 chr4:38894380 C/T cg06935464 chr4:38784597 TLR10 -0.39 -6.62 -0.34 1.39e-10 Breast cancer; LIHC cis rs9733 0.650 rs12125672 chr1:150554470 A/T cg18016565 chr1:150552671 MCL1 -0.54 -10.95 -0.51 4.15e-24 Tonsillectomy; LIHC cis rs941873 0.868 rs4980063 chr10:81105844 A/T cg09469691 chr10:81107165 PPIF 0.7 10.78 0.5 1.55e-23 Height; LIHC cis rs1949733 0.598 rs869602 chr4:8535371 G/T cg11789530 chr4:8429930 ACOX3 -0.63 -9.02 -0.44 1.38e-17 Response to antineoplastic agents; LIHC cis rs2832191 0.716 rs2692625 chr21:30446360 C/G cg08807101 chr21:30365312 RNF160 0.78 11.71 0.54 7.24e-27 Dental caries; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg12419862 chr22:24373484 LOC391322 -0.65 -9.77 -0.47 4.87e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1552244 0.572 rs2054478 chr3:10172211 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.89 -9.41 -0.45 7.39e-19 Alzheimer's disease; LIHC cis rs651907 0.535 rs34743741 chr3:101532448 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.11 0.48 3.29e-21 Colorectal cancer; LIHC cis rs6088590 1.000 rs6088590 chr20:33313566 T/C cg06115741 chr20:33292138 TP53INP2 0.61 8.8 0.43 6.92e-17 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05494465 chr13:74710406 NA 0.42 6.4 0.33 5.15e-10 Lung function (FEV1/FVC); LIHC cis rs317689 0.819 rs317683 chr12:69713630 T/G cg14784868 chr12:69753453 YEATS4 0.6 8.81 0.43 6.62e-17 Response to diuretic therapy; LIHC cis rs3008870 1.000 rs2182143 chr1:67378936 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.6 0.67 8.6e-46 Lymphocyte percentage of white cells; LIHC cis rs6088580 0.634 rs6058052 chr20:33047084 A/G cg08999081 chr20:33150536 PIGU 0.67 13.39 0.59 3.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg24503407 chr1:205819492 PM20D1 0.72 10.24 0.48 1.21e-21 Menarche (age at onset); LIHC cis rs12586317 0.586 rs2295103 chr14:35515920 C/G cg16230307 chr14:35515116 FAM177A1 0.82 13.59 0.59 5.98e-34 Psoriasis; LIHC cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg20090690 chr10:134436459 INPP5A 0.44 5.71 0.3 2.43e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6977660 1.000 rs10279601 chr7:19822171 G/A cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs7772486 0.597 rs1970306 chr6:146154543 A/G cg23711669 chr6:146136114 FBXO30 0.63 9.63 0.46 1.44e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs7927592 0.956 rs12281742 chr11:68303629 C/T cg01657329 chr11:68192670 LRP5 0.48 6.44 0.33 4.03e-10 Total body bone mineral density; LIHC cis rs7264396 0.580 rs2425173 chr20:34445142 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.57 -8.0 -0.4 1.94e-14 Total cholesterol levels; LIHC cis rs7312933 0.558 rs55702525 chr12:42814309 T/C cg17420585 chr12:42539391 GXYLT1 0.35 5.71 0.3 2.39e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs763121 0.819 rs138700 chr22:39129999 A/G cg21395723 chr22:39101663 GTPBP1 0.36 6.01 0.31 4.66e-9 Menopause (age at onset); LIHC cis rs17756712 0.570 rs1122256 chr6:611969 A/C cg14374089 chr6:596013 EXOC2 -0.48 -6.57 -0.33 1.89e-10 Vertical cup-disc ratio; LIHC cis rs8010715 0.816 rs1134340 chr14:24594213 C/T cg23112188 chr14:24563095 PCK2 -0.29 -5.98 -0.31 5.56e-9 IgG glycosylation; LIHC cis rs1564271 0.528 rs1980756 chr10:26979371 G/C cg13837822 chr10:26931731 LOC731789 0.38 7.19 0.36 4.02e-12 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs4820294 1.000 rs62236668 chr22:38063870 G/A cg10587741 chr22:38071170 LGALS1 0.72 12.53 0.56 6.87e-30 Fat distribution (HIV); LIHC cis rs644799 1.000 rs514170 chr11:95556696 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7131987 0.650 rs10843384 chr12:29472409 C/T cg16970926 chr12:29381810 FAR2 0.29 5.98 0.31 5.47e-9 QT interval; LIHC cis rs950169 0.580 rs35516100 chr15:85195430 C/T cg03959625 chr15:84868606 LOC388152 0.44 6.3 0.32 8.99e-10 Schizophrenia; LIHC cis rs61990749 0.544 rs1477259 chr14:78256138 C/G cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.14 0.48 2.63e-21 Fibroblast growth factor basic levels; LIHC cis rs7107174 1.000 rs4245459 chr11:78065959 T/G cg02023728 chr11:77925099 USP35 0.46 8.7 0.43 1.46e-16 Testicular germ cell tumor; LIHC cis rs3741798 1.000 rs17375328 chr12:12485292 T/C cg08615371 chr12:12503544 MANSC1 0.99 7.89 0.39 4.09e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs17685 0.725 rs1044483 chr7:75659815 T/C cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.23 0.32 1.41e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8060686 0.565 rs75735284 chr16:68126635 C/A cg05110241 chr16:68378359 PRMT7 -0.6 -6.77 -0.34 5.6e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs2115630 0.967 rs7171167 chr15:85239123 A/T cg11189052 chr15:85197271 WDR73 -0.39 -5.86 -0.3 1.08e-8 P wave terminal force; LIHC cis rs9640161 0.789 rs6964110 chr7:150041836 A/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.45 -7.84 -0.39 5.9e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs4819052 0.851 rs914218 chr21:46698445 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.24 0.41 3.82e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7503168 1.000 rs35237539 chr17:33929582 A/G cg20932281 chr17:33905541 PEX12 0.54 7.06 0.36 9.38e-12 Plateletcrit; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg20102877 chr2:27665638 KRTCAP3 -0.41 -5.72 -0.3 2.39e-8 Total body bone mineral density; LIHC cis rs208520 0.526 rs9351542 chr6:66788571 A/G cg07460842 chr6:66804631 NA -1.03 -20.04 -0.73 1.2e-59 Exhaled nitric oxide output; LIHC cis rs2073499 1.000 rs3806708 chr3:50306249 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.65 7.37 0.37 1.29e-12 Schizophrenia; LIHC cis rs748404 0.578 rs512628 chr15:43618734 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.58 10.44 0.49 2.41e-22 Lung cancer; LIHC cis rs12644436 0.576 rs3857037 chr4:88780468 G/A cg06891869 chr4:88767617 MEPE 0.43 7.59 0.38 3.12e-13 HIV-1 viral setpoint; LIHC cis rs1538970 0.962 rs9429158 chr1:45821393 A/G cg05343316 chr1:45956843 TESK2 0.54 8.18 0.4 5.73e-15 Platelet count; LIHC cis rs8114671 0.562 rs6088655 chr20:33527838 A/G cg07148914 chr20:33460835 GGT7 0.64 9.72 0.47 7.19e-20 Height; LIHC cis rs6963495 0.818 rs55691539 chr7:105165774 T/C cg19920283 chr7:105172520 RINT1 0.69 6.53 0.33 2.32e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg17971929 chr21:40555470 PSMG1 0.82 9.98 0.47 9.74e-21 Cognitive function; LIHC cis rs9522267 0.535 rs11069899 chr13:112231553 T/C cg10483660 chr13:112241077 NA -0.21 -5.75 -0.3 2.01e-8 Hepatitis; LIHC cis rs7833986 0.534 rs10504198 chr8:57006254 G/C cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.06e-16 Height; LIHC cis rs1062177 0.502 rs10463321 chr5:151323905 T/G cg00977110 chr5:151150581 G3BP1 0.46 5.93 0.31 7.43e-9 Preschool internalizing problems; LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg24209194 chr3:40518798 ZNF619 0.63 9.45 0.46 5.36e-19 Renal cell carcinoma; LIHC cis rs370915 1.000 rs9685837 chr4:187818466 C/T cg19519643 chr4:187840862 NA -0.44 -7.19 -0.36 4.14e-12 Gout; LIHC cis rs2070488 0.766 rs4679050 chr3:38482007 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.31 0.55 4.45e-29 Electrocardiographic conduction measures; LIHC cis rs9596270 0.772 rs706603 chr13:50855023 A/G cg17741629 chr13:50024703 SETDB2 -0.53 -5.74 -0.3 2.14e-8 Multiple sclerosis; LIHC cis rs12579753 1.000 rs7975863 chr12:82227288 C/T cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs10464366 0.571 rs13233049 chr7:39187536 C/T cg10621924 chr7:39171070 POU6F2 0.41 6.45 0.33 3.86e-10 IgG glycosylation; LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg17178900 chr1:205818956 PM20D1 0.66 9.92 0.47 1.53e-20 Menarche (age at onset); LIHC trans rs2243480 0.522 rs778717 chr7:65848151 G/C cg10756647 chr7:56101905 PSPH 1.07 11.64 0.53 1.29e-26 Diabetic kidney disease; LIHC cis rs6964587 1.000 rs7805077 chr7:91644553 A/G cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 11.98 0.54 7.77e-28 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25152348 chr22:50946712 NCAPH2;LMF2 0.67 8.82 0.43 5.84e-17 Lung function (FEV1/FVC); LIHC cis rs1577917 0.655 rs2758848 chr6:86347605 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.29 -0.41 2.54e-15 Response to antipsychotic treatment; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg16132339 chr22:24313637 DDTL;DDT 0.78 15.41 0.64 4.84e-41 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg23982607 chr1:1823379 GNB1 0.55 9.05 0.44 1.14e-17 Body mass index; LIHC cis rs3853824 0.965 rs1879145 chr17:54902055 A/G cg13675837 chr17:54910204 DGKE 0.42 5.96 0.31 6.25e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg21016266 chr12:122356598 WDR66 0.54 8.79 0.43 7.46e-17 Mean corpuscular volume; LIHC cis rs2303745 0.589 rs891018 chr19:17396761 C/T cg04248312 chr19:17393744 ANKLE1 0.74 12.33 0.55 3.64e-29 Systemic lupus erythematosus; LIHC cis rs921968 0.643 rs711191 chr2:219386084 T/A cg17980119 chr2:219472607 PLCD4 0.35 6.05 0.31 3.84e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs61990749 0.597 rs176946 chr14:78178439 C/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.91 -0.39 3.71e-14 Fibroblast growth factor basic levels; LIHC cis rs11190604 0.767 rs11190531 chr10:102187310 T/A cg07080220 chr10:102295463 HIF1AN 0.47 6.87 0.35 3.04e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9628987 0.569 rs902355 chr1:8433124 T/C cg20416874 chr1:8611966 RERE 0.49 5.99 0.31 5.45e-9 Breast cancer; LIHC cis rs8072100 0.576 rs12948299 chr17:45403057 T/C cg25173405 chr17:45401733 C17orf57 -0.58 -7.55 -0.38 3.92e-13 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs11608355 0.545 rs6606723 chr12:109905044 C/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs2404602 0.692 rs12595586 chr15:77172210 A/G cg23625390 chr15:77176239 SCAPER 0.35 5.73 0.3 2.21e-8 Blood metabolite levels; LIHC cis rs965469 0.895 rs6139124 chr20:3398144 C/T cg25506879 chr20:3388711 C20orf194 -0.53 -6.21 -0.32 1.51e-9 IFN-related cytopenia; LIHC cis rs7582180 0.629 rs4851295 chr2:100945605 T/C cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.97e-16 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs4698200 chr4:17657051 G/A cg02297831 chr4:17616191 MED28 0.49 7.63 0.38 2.42e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs1973993 0.745 rs986427 chr1:96932736 A/G cg10631902 chr5:14652156 NA -0.32 -6.9 -0.35 2.5e-11 Weight; LIHC cis rs892961 0.932 rs747481 chr17:75412143 A/G cg05865280 chr17:75406074 SEPT9 0.65 13.54 0.59 9.78e-34 Airflow obstruction; LIHC trans rs1814175 0.935 rs6485999 chr11:49658986 G/C cg15704280 chr7:45808275 SEPT13 -1.01 -21.71 -0.76 2.59e-66 Height; LIHC cis rs8013055 0.846 rs10136015 chr14:105973469 A/C cg19700328 chr14:106028568 NA -0.35 -7.56 -0.38 3.76e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs1371867 0.846 rs1660323 chr8:101278724 T/A cg06636551 chr8:101224915 SPAG1 -0.51 -9.54 -0.46 2.72e-19 Atrioventricular conduction; LIHC cis rs6952808 0.531 rs3779002 chr7:2183219 C/T cg21782813 chr7:2030301 MAD1L1 0.38 6.44 0.33 4.07e-10 Bipolar disorder and schizophrenia; LIHC trans rs4843747 0.519 rs12599755 chr16:88107006 A/G cg09572067 chr16:29127029 RRN3P2 0.53 8.44 0.42 9.06e-16 Menopause (age at onset); LIHC cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg18252515 chr7:66147081 NA -1.25 -16.49 -0.67 2.24e-45 Diabetic kidney disease; LIHC cis rs1865760 0.566 rs4529296 chr6:26083135 C/G cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC cis rs875971 0.651 rs2420596 chr7:65915983 T/C cg11764359 chr7:65958608 NA 0.83 14.41 0.61 4e-37 Aortic root size; LIHC cis rs9814567 1.000 rs4367113 chr3:134287975 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2380220 0.576 rs4368819 chr6:96031109 T/G cg23517279 chr6:96025343 MANEA 0.56 5.72 0.3 2.28e-8 Behavioural disinhibition (generation interaction); LIHC cis rs11673344 0.808 rs57916401 chr19:37644051 T/C cg27390819 chr19:37464633 NA -0.49 -5.95 -0.31 6.66e-9 Obesity-related traits; LIHC cis rs477692 0.905 rs489966 chr10:131422115 C/G cg05714579 chr10:131428358 MGMT -0.48 -7.98 -0.4 2.2e-14 Response to temozolomide; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg04155289 chr7:94953770 PON1 -0.48 -8.51 -0.42 5.38e-16 Paraoxonase activity; LIHC cis rs6933660 0.800 rs963193 chr6:151789355 G/T cg10883421 chr6:151773342 RMND1;C6orf211 -0.62 -10.02 -0.48 6.72e-21 Menarche (age at onset); LIHC cis rs11758351 0.660 rs11757754 chr6:26219744 A/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs3770081 1.000 rs13390702 chr2:86237935 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.81 -9.0 -0.44 1.58e-17 Facial emotion recognition (sad faces); LIHC cis rs425277 0.958 rs262688 chr1:2113565 T/G cg24578937 chr1:2090814 PRKCZ 0.48 8.47 0.42 7.46e-16 Height; LIHC cis rs11025559 0.812 rs11025583 chr11:20513260 C/T cg19653624 chr11:20408972 PRMT3 0.46 6.06 0.31 3.64e-9 Pursuit maintenance gain; LIHC cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg00204748 chr12:29376779 FAR2 0.43 7.89 0.39 4.06e-14 QT interval; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19789021 chr5:95158141 GLRX 0.4 6.12 0.31 2.52e-9 Calcium levels; LIHC cis rs3862030 0.500 rs11191327 chr10:104303883 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.84 0.57 4.73e-31 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs7587476 0.822 rs13018304 chr2:215682218 T/G cg04530015 chr2:215796436 ABCA12 -0.38 -6.22 -0.32 1.43e-9 Neuroblastoma; LIHC trans rs916888 0.773 rs199457 chr17:44795469 C/T cg16836995 chr17:43662488 NA -0.76 -7.8 -0.39 7.78e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2075371 0.966 rs2544214 chr7:133985736 G/A cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC cis rs7959452 0.590 rs11177644 chr12:69785748 A/G cg22834771 chr12:69754056 YEATS4 -0.51 -9.16 -0.44 4.93e-18 Blood protein levels; LIHC cis rs6062302 0.548 rs6089940 chr20:62252695 C/T cg09650180 chr20:62225654 GMEB2 -0.39 -6.07 -0.31 3.33e-9 Glioblastoma; LIHC cis rs2153535 0.580 rs1932276 chr6:8442593 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs6076065 0.748 rs4142246 chr20:23388975 A/G cg11657817 chr20:23433608 CST11 0.32 6.78 0.34 5.14e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg06873352 chr17:61820015 STRADA 0.55 8.29 0.41 2.6e-15 Height; LIHC cis rs3015497 1.000 rs3015497 chr14:51113398 T/C cg09863266 chr14:51125203 SAV1 -0.39 -6.4 -0.33 5.05e-10 Mean platelet volume; LIHC cis rs67311347 0.713 rs114569261 chr3:40314580 G/A cg13409248 chr3:40428643 ENTPD3 0.4 6.37 0.33 6.22e-10 Renal cell carcinoma; LIHC cis rs9916302 0.851 rs4794810 chr17:37603774 T/C cg03013999 chr17:37608204 MED1 0.35 5.83 0.3 1.31e-8 Glomerular filtration rate (creatinine); LIHC cis rs651907 0.557 rs1031710 chr3:101463895 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.45 -0.33 3.81e-10 Colorectal cancer; LIHC cis rs10498514 1.000 rs17101854 chr14:64906265 A/G cg25134081 chr14:64931936 AKAP5 -1.06 -6.87 -0.35 3.1e-11 Cognitive performance; LIHC cis rs826838 0.874 rs11183816 chr12:38834656 T/G cg13010199 chr12:38710504 ALG10B 0.65 7.82 0.39 6.73e-14 Heart rate; LIHC cis rs7296418 0.630 rs11608305 chr12:123791165 C/G cg00376283 chr12:123451042 ABCB9 0.62 10.22 0.48 1.39e-21 Platelet count; LIHC cis rs7845219 0.544 rs7017487 chr8:95922752 A/G cg13393036 chr8:95962371 TP53INP1 0.32 6.14 0.32 2.29e-9 Type 2 diabetes; LIHC cis rs546131 0.642 rs11602886 chr11:34841843 G/A cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.49 -0.33 3.05e-10 Lung disease severity in cystic fibrosis; LIHC cis rs801193 0.967 rs2707853 chr7:66214010 G/A cg11764359 chr7:65958608 NA 0.71 10.63 0.5 5.35e-23 Aortic root size; LIHC cis rs1843834 0.858 rs2047136 chr2:225511361 A/T cg22509189 chr2:225307070 NA -0.61 -7.44 -0.37 8.3e-13 IgE levels in asthmatics (D.p. specific); LIHC cis rs3008870 0.920 rs3008865 chr1:67402838 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg04025307 chr7:1156635 C7orf50 0.6 10.3 0.49 7.84e-22 Longevity;Endometriosis; LIHC cis rs10791097 0.694 rs4937581 chr11:130740335 T/C cg22079354 chr11:130786696 SNX19 0.42 6.02 0.31 4.43e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1707322 1.000 rs6657720 chr1:46386269 G/A cg03146154 chr1:46216737 IPP 0.47 7.62 0.38 2.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg14004847 chr7:1930337 MAD1L1 -0.42 -6.14 -0.32 2.25e-9 Bipolar disorder and schizophrenia; LIHC cis rs9457247 1.000 rs1819333 chr6:167373547 G/T cg23791538 chr6:167370224 RNASET2 -0.67 -11.28 -0.52 2.65e-25 Crohn's disease; LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg21782813 chr7:2030301 MAD1L1 0.57 10.35 0.49 5.24e-22 Bipolar disorder and schizophrenia; LIHC cis rs9326248 1.000 rs3736120 chr11:117032125 G/T cg10130564 chr11:117069849 TAGLN 0.34 5.73 0.3 2.25e-8 Blood protein levels; LIHC cis rs7258465 0.931 rs271626 chr19:18627067 C/T cg01065977 chr19:18549689 ISYNA1 0.39 5.9 0.3 8.96e-9 Breast cancer; LIHC cis rs703842 1.000 rs1875124 chr12:58196802 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.3 0.61 1.07e-36 Multiple sclerosis; LIHC cis rs2404602 0.716 rs17461634 chr15:76764107 G/A cg03037974 chr15:76606532 NA 0.79 16.19 0.66 3.6e-44 Blood metabolite levels; LIHC cis rs9814567 0.896 rs10935123 chr3:134345327 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.59 -9.88 -0.47 2.04e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1707322 0.691 rs11211175 chr1:46220884 C/G cg06784218 chr1:46089804 CCDC17 0.4 7.49 0.38 6.04e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs72627509 0.638 rs78933653 chr4:57854840 A/G cg26694713 chr4:57773883 REST 0.65 8.54 0.42 4.32e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7772486 0.790 rs6917482 chr6:146243581 C/T cg23711669 chr6:146136114 FBXO30 -0.64 -11.11 -0.51 1.08e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs7927592 0.913 rs67947146 chr11:68314980 C/T cg01657329 chr11:68192670 LRP5 -0.47 -6.15 -0.32 2.22e-9 Total body bone mineral density; LIHC cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.41 0.45 7.44e-19 Bipolar disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24648061 chr7:107114615 COG5;GPR22 0.36 6.59 0.34 1.69e-10 Cognitive function; LIHC cis rs11711311 1.000 rs7622515 chr3:113472538 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.44 8.47 0.42 7.11e-16 IgG glycosylation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02581963 chr10:102133317 C10orf75 0.47 6.42 0.33 4.45e-10 Lung function (FEV1/FVC); LIHC cis rs918629 0.530 rs11739652 chr5:95238582 C/G cg10483112 chr5:95245456 ELL2 -0.36 -6.55 -0.33 2.08e-10 IgG glycosylation; LIHC cis rs2066819 1.000 rs75754909 chr12:56726349 A/G cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs12971120 0.891 rs3764510 chr18:72166846 A/G cg25817165 chr18:72167213 CNDP2 -0.71 -12.44 -0.56 1.47e-29 Refractive error; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23110891 chr1:94344782 DNTTIP2 -0.44 -6.15 -0.32 2.14e-9 Pancreatic cancer; LIHC cis rs11122272 0.764 rs4486439 chr1:231477470 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -11.08 -0.51 1.35e-24 Hemoglobin concentration; LIHC cis rs6960043 0.905 rs2215381 chr7:15054935 G/T cg19272540 chr7:15055459 NA 0.25 6.77 0.34 5.53e-11 Type 2 diabetes; LIHC cis rs8044868 0.566 rs3812984 chr16:72207797 C/T cg16558253 chr16:72132732 DHX38 -0.38 -6.27 -0.32 1.08e-9 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg06238570 chr21:40685208 BRWD1 0.58 6.85 0.35 3.37e-11 Cognitive function; LIHC cis rs62158211 0.955 rs1823125 chr2:114090412 C/T cg17784749 chr2:114082611 LOC440839 -0.6 -7.85 -0.39 5.41e-14 Sleep duration (oversleepers vs undersleepers);Sleep traits (multi-trait analysis);Sleep duration; LIHC cis rs751728 0.965 rs9394165 chr6:33731408 G/A cg25922239 chr6:33757077 LEMD2 0.46 7.51 0.38 5.14e-13 Crohn's disease; LIHC cis rs7959452 0.868 rs10878967 chr12:69740869 T/C cg14784868 chr12:69753453 YEATS4 0.74 12.52 0.56 7.42e-30 Blood protein levels; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs17152411 0.895 rs7080475 chr10:126585767 A/G cg07906193 chr10:126599966 NA 0.44 6.96 0.35 1.78e-11 Height; LIHC cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg03264133 chr6:25882463 NA 0.47 6.77 0.34 5.72e-11 Blood metabolite levels; LIHC cis rs6426558 0.537 rs12039370 chr1:227326472 A/G cg10327440 chr1:227177885 CDC42BPA -0.45 -6.95 -0.35 1.81e-11 Neutrophil percentage of white cells; LIHC cis rs6089829 0.962 rs9679865 chr20:61666132 C/G cg03213289 chr20:61660250 NA 0.5 8.97 0.44 1.99e-17 Prostate cancer (SNP x SNP interaction); LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg00975115 chr16:30958403 FBXL19 0.45 6.38 0.33 5.84e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs6867032 1.000 rs61177713 chr5:2017255 G/A cg26168224 chr5:2018326 NA 0.3 7.45 0.37 7.61e-13 Gut microbiome composition (winter); LIHC cis rs34540877 1.000 rs12981834 chr19:33124749 G/A cg22980127 chr19:33182716 NUDT19 1.01 6.75 0.34 6.37e-11 Red cell distribution width; LIHC cis rs796364 1.000 rs4263095 chr2:200830137 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.75 -8.99 -0.44 1.78e-17 Schizophrenia; LIHC cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg11764359 chr7:65958608 NA 0.69 9.32 0.45 1.45e-18 Aortic root size; LIHC cis rs8081395 0.737 rs4968401 chr17:58040730 T/C cg02344993 chr17:57696989 CLTC -0.37 -5.9 -0.3 8.83e-9 White blood cell count; LIHC cis rs2115630 1.000 rs56074163 chr15:85351332 C/T cg12501888 chr15:85177176 SCAND2 -0.48 -7.38 -0.37 1.19e-12 P wave terminal force; LIHC cis rs12765878 0.967 rs10883941 chr10:105650782 C/T cg11005552 chr10:105648138 OBFC1 0.39 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs826838 0.904 rs10876086 chr12:39188208 C/A cg13010199 chr12:38710504 ALG10B 0.5 6.02 0.31 4.6e-9 Heart rate; LIHC cis rs748404 0.697 rs513970 chr15:43579566 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 6.81 0.35 4.44e-11 Lung cancer; LIHC cis rs1538970 0.924 rs11211118 chr1:45930270 A/C cg05343316 chr1:45956843 TESK2 0.58 8.5 0.42 5.77e-16 Platelet count; LIHC cis rs12478296 0.581 rs56142391 chr2:242992248 C/T cg18898632 chr2:242989856 NA -0.5 -7.21 -0.36 3.65e-12 Obesity-related traits; LIHC trans rs7721647 0.853 rs10058587 chr5:90872543 G/C cg11567849 chr6:111751012 REV3L -0.49 -6.08 -0.31 3.14e-9 Breast cancer; LIHC cis rs11758351 1.000 rs3734530 chr6:26195408 G/C cg16070018 chr6:26224392 HIST1H3E 0.57 6.81 0.35 4.47e-11 Gout;Renal underexcretion gout; LIHC cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg10862848 chr6:42927986 GNMT -0.26 -6.26 -0.32 1.12e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9467773 0.626 rs9379860 chr6:26370605 T/C cg09904177 chr6:26538194 HMGN4 -0.36 -5.8 -0.3 1.53e-8 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.656 rs10846664 chr12:122823777 C/T cg05707623 chr12:122985044 ZCCHC8 0.54 7.22 0.36 3.34e-12 Body mass index; LIHC cis rs10924970 0.649 rs9787250 chr1:235387854 A/T cg26050004 chr1:235667680 B3GALNT2 0.4 5.83 0.3 1.27e-8 Asthma; LIHC cis rs1707322 0.717 rs2991989 chr1:46082965 C/T cg06784218 chr1:46089804 CCDC17 -0.41 -7.45 -0.37 7.94e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9649213 0.593 rs6949214 chr7:97960233 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.12e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.48 0.56 1.07e-29 Alzheimer's disease; LIHC cis rs9318086 0.534 rs10507334 chr13:24369787 G/A cg25267304 chr13:24462978 PCOTH;MIPEP -0.35 -5.84 -0.3 1.18e-8 Myopia (pathological); LIHC cis rs2549003 1.000 rs17848418 chr5:131821188 C/T cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs735396 0.770 rs1169300 chr12:121431225 G/A cg25281562 chr12:121454272 C12orf43 0.36 6.23 0.32 1.33e-9 N-glycan levels; LIHC cis rs2976388 0.609 rs2257796 chr8:143808667 T/C cg06565975 chr8:143823917 SLURP1 0.34 6.69 0.34 9.21e-11 Urinary tract infection frequency; LIHC cis rs769267 0.792 rs4808961 chr19:19577215 C/G cg15052019 chr19:19431593 KIAA0892;SF4 0.41 5.73 0.3 2.15e-8 Tonsillectomy; LIHC cis rs12701220 0.655 rs34344742 chr7:1149288 C/G cg00990874 chr7:1149470 C7orf50 -0.71 -10.14 -0.48 2.72e-21 Bronchopulmonary dysplasia; LIHC cis rs6120849 0.663 rs6088662 chr20:33547633 A/C cg24642439 chr20:33292090 TP53INP2 0.67 7.75 0.39 1.05e-13 Protein C levels; LIHC cis rs240764 0.658 rs9322213 chr6:101248480 T/C cg09795085 chr6:101329169 ASCC3 -0.41 -6.01 -0.31 4.63e-9 Neuroticism; LIHC cis rs9420 0.961 rs11570190 chr11:57560452 A/C cg19752551 chr11:57585705 CTNND1 -0.53 -7.48 -0.37 6.33e-13 Schizophrenia; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg22887498 chr19:39401301 NA 0.45 6.63 0.34 1.28e-10 Bilirubin levels; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.9 -0.3 8.51e-9 Total body bone mineral density; LIHC cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.47 6.56 0.33 1.97e-10 Intelligence (multi-trait analysis); LIHC cis rs17253792 0.822 rs17683656 chr14:56053361 C/T cg01858014 chr14:56050164 KTN1 0.79 7.72 0.39 1.27e-13 Putamen volume; LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs4407350 0.715 rs3827400 chr22:44890604 T/C cg11695653 chr22:44894386 LDOC1L -0.37 -6.23 -0.32 1.33e-9 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.13 -16.75 -0.67 2.03e-46 Gut microbiome composition (summer); LIHC cis rs74233809 1.000 rs11191551 chr10:104850835 A/G cg03493300 chr10:104813866 CNNM2 0.46 6.29 0.32 9.93e-10 Birth weight; LIHC cis rs568617 0.626 rs10896050 chr11:65577516 G/T cg04055107 chr11:65626734 MUS81;CFL1 0.48 5.97 0.31 6.06e-9 Crohn's disease; LIHC cis rs1577917 0.958 rs6921315 chr6:86471668 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.46 -0.42 8.12e-16 Response to antipsychotic treatment; LIHC cis rs12477438 0.508 rs2516832 chr2:99771268 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.81 0.65 1.23e-42 Chronic sinus infection; LIHC cis rs17253792 0.818 rs78393484 chr14:56065802 T/C cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg13877915 chr19:58951672 ZNF132 0.65 11.06 0.51 1.66e-24 Uric acid clearance; LIHC cis rs11864453 0.826 rs6499559 chr16:72132064 G/C cg01557791 chr16:72042693 DHODH -0.53 -8.6 -0.42 3e-16 Fibrinogen levels; LIHC cis rs12579753 0.912 rs4417392 chr12:82158722 C/A cg07988820 chr12:82153109 PPFIA2 -0.49 -5.94 -0.31 6.82e-9 Resting heart rate; LIHC cis rs16828019 0.777 rs67460888 chr1:41469337 T/C cg03962019 chr1:41807865 NA 0.52 7.06 0.36 9.17e-12 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg11062466 chr8:58055876 NA 0.41 6.02 0.31 4.59e-9 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1577917 1.000 rs117907570 chr6:86601283 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -8.06 -0.4 1.25e-14 Response to antipsychotic treatment; LIHC cis rs7903847 0.656 rs12412478 chr10:99134923 C/T cg06359132 chr10:99160096 RRP12 -0.41 -6.06 -0.31 3.55e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg05665937 chr4:1216051 CTBP1 0.47 6.31 0.32 8.45e-10 Obesity-related traits; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg12419862 chr22:24373484 LOC391322 -0.69 -10.26 -0.49 1.03e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs801193 0.569 rs13242290 chr7:66121885 G/A cg18876405 chr7:65276391 NA -0.31 -5.72 -0.3 2.34e-8 Aortic root size; LIHC trans rs8073060 0.586 rs2523114 chr17:34023762 G/A cg19694781 chr19:47549865 TMEM160 -1.19 -12.33 -0.55 3.78e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg22800045 chr5:56110881 MAP3K1 0.66 8.35 0.41 1.71e-15 Initial pursuit acceleration; LIHC cis rs55823223 0.564 rs9894009 chr17:73850414 C/T cg19302996 chr17:73780495 UNK -0.54 -6.71 -0.34 8.24e-11 Psoriasis; LIHC cis rs7412746 0.658 rs12405726 chr1:150956128 G/A cg17724175 chr1:150552817 MCL1 0.4 7.54 0.38 4.2e-13 Melanoma; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg23017654 chr17:40346486 GHDC 0.41 6.08 0.31 3.19e-9 Migraine with aura; LIHC cis rs3008870 0.755 rs1121824 chr1:67475616 C/A cg02640540 chr1:67518911 SLC35D1 0.44 6.83 0.35 3.83e-11 Lymphocyte percentage of white cells; LIHC cis rs7512552 0.809 rs1694363 chr1:150368677 T/G cg15654264 chr1:150340011 RPRD2 0.7 11.1 0.51 1.21e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs4713118 0.513 rs149959 chr6:28013854 T/C cg16479474 chr6:28041457 NA 0.39 6.38 0.33 5.78e-10 Parkinson's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01191584 chr2:27594002 SNX17;EIF2B4 0.44 6.18 0.32 1.78e-9 Lung function (FEV1/FVC); LIHC cis rs2579500 0.538 rs17634791 chr2:97328852 C/T cg26665480 chr2:98280029 ACTR1B -0.4 -5.92 -0.3 7.78e-9 Eosinophil counts;Eosinophil percentage of white cells; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21157519 chr14:53162301 ERO1L -0.48 -6.33 -0.32 7.61e-10 Systolic blood pressure; LIHC cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.15 -0.44 5.33e-18 Bipolar disorder; LIHC cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg05564831 chr3:52568323 NT5DC2 0.37 6.04 0.31 3.93e-9 Bipolar disorder; LIHC cis rs4517514 0.509 rs11018869 chr11:89865168 A/G cg05041596 chr11:89867385 NAALAD2 0.41 6.51 0.33 2.63e-10 Trans fatty acid levels; LIHC cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg05590025 chr7:65112418 INTS4L2 -0.62 -6.65 -0.34 1.16e-10 Diabetic kidney disease; LIHC cis rs16958440 0.867 rs74411203 chr18:44677466 G/A cg17192377 chr18:44677553 HDHD2 0.93 8.68 0.42 1.66e-16 Sitting height ratio; LIHC cis rs6748734 1.000 rs3936203 chr2:241834654 C/T cg04034577 chr2:241836375 C2orf54 0.41 7.97 0.4 2.33e-14 Urinary metabolites; LIHC cis rs6542838 0.702 rs6419564 chr2:99534113 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.54 -0.33 2.19e-10 Fear of minor pain; LIHC cis rs35522438 1 rs35522438 chr7:91872872 A/AT cg17063962 chr7:91808500 NA 1.05 21.49 0.76 1.96e-65 Breast cancer; LIHC cis rs1577917 1.000 rs10944161 chr6:86630376 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7903847 0.642 rs11189172 chr10:99135215 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.66 -0.34 1.06e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11548363 chr19:13068138 GADD45GIP1 0.5 6.33 0.32 7.53e-10 Lung function (FEV1/FVC); LIHC cis rs6964587 0.626 rs10243083 chr7:91552530 G/A cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.23e-24 Breast cancer; LIHC cis rs4699052 0.928 rs2126473 chr4:104141533 G/C cg16532752 chr4:104119610 CENPE -0.42 -6.71 -0.34 8.25e-11 Testicular germ cell tumor; LIHC trans rs2797160 0.967 rs4897151 chr6:125993202 T/G cg05039488 chr6:79577232 IRAK1BP1 -0.44 -6.33 -0.32 7.82e-10 Endometrial cancer; LIHC cis rs644148 0.933 rs565819 chr19:44967714 A/G cg15540054 chr19:45004280 ZNF180 0.77 11.42 0.53 8.63e-26 Personality dimensions; LIHC cis rs12477438 0.520 rs10865029 chr2:99718298 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.53 0.64 1.5e-41 Chronic sinus infection; LIHC cis rs2274273 0.773 rs8012380 chr14:55735010 T/G cg01864836 chr14:55583639 NA -0.4 -7.32 -0.37 1.73e-12 Protein biomarker; LIHC trans rs4650994 0.525 rs4316329 chr1:178509333 C/T cg05059571 chr16:84539110 KIAA1609 -0.42 -7.24 -0.36 2.98e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs8017423 0.934 rs11159952 chr14:90684874 T/C cg04374321 chr14:90722782 PSMC1 0.72 13.74 0.6 1.62e-34 Mortality in heart failure; LIHC cis rs60871478 1.000 rs62432860 chr7:807522 G/C cg27478167 chr7:817139 HEATR2 -0.41 -5.85 -0.3 1.13e-8 Cerebrospinal P-tau181p levels; LIHC cis rs6088580 0.524 rs6088560 chr20:33228549 T/C cg08999081 chr20:33150536 PIGU -0.43 -7.38 -0.37 1.2e-12 Glomerular filtration rate (creatinine); LIHC cis rs904251 0.504 rs1757188 chr6:37483808 A/G cg08126542 chr6:37504118 NA -0.36 -6.26 -0.32 1.18e-9 Cognitive performance; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg01744729 chr13:113474194 ATP11A 0.46 6.82 0.35 4.05e-11 Immature fraction of reticulocytes; LIHC cis rs9297145 0.761 rs28545226 chr7:98732472 A/T cg05967295 chr7:98741636 SMURF1 0.68 9.73 0.47 6.58e-20 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs9814567 1.000 rs7619451 chr3:134233238 A/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -5.81 -0.3 1.42e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.48 -7.26 -0.37 2.6e-12 Menarche (age at onset); LIHC cis rs9325144 0.513 rs12313652 chr12:38665412 G/A cg26384229 chr12:38710491 ALG10B -0.59 -8.07 -0.4 1.19e-14 Morning vs. evening chronotype; LIHC cis rs6088580 0.505 rs6141503 chr20:33274469 G/A cg08999081 chr20:33150536 PIGU -0.43 -7.21 -0.36 3.67e-12 Glomerular filtration rate (creatinine); LIHC cis rs2842992 0.872 rs9456440 chr6:160074463 G/T cg11366901 chr6:160182831 ACAT2 0.94 14.97 0.63 2.48e-39 Age-related macular degeneration (geographic atrophy); LIHC cis rs2274273 0.840 rs2009291 chr14:55838230 A/C cg01864836 chr14:55583639 NA 0.38 6.9 0.35 2.5e-11 Protein biomarker; LIHC cis rs1552244 0.572 rs67439440 chr3:10169503 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC cis rs12744310 0.887 rs1892419 chr1:41781151 T/C cg03962019 chr1:41807865 NA 0.39 6.23 0.32 1.36e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg00656387 chr3:40428638 ENTPD3 0.48 7.9 0.39 3.83e-14 Renal cell carcinoma; LIHC cis rs798554 0.836 rs798500 chr7:2790685 C/T cg19524238 chr7:2802976 GNA12 0.38 5.73 0.3 2.18e-8 Height; LIHC cis rs9814567 0.929 rs13088413 chr3:134309977 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.22 0.32 1.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2075671 0.903 rs62482252 chr7:100274063 C/A cg20848291 chr7:100343083 ZAN -0.46 -6.35 -0.32 6.84e-10 Other erythrocyte phenotypes; LIHC cis rs7044106 0.762 rs10760115 chr9:123476952 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.73 0.39 1.18e-13 Hip circumference adjusted for BMI; LIHC cis rs10927875 0.757 rs4661679 chr1:16321010 C/T cg21385522 chr1:16154831 NA 0.49 6.2 0.32 1.63e-9 Dilated cardiomyopathy; LIHC cis rs6840360 0.571 rs7664663 chr4:152508014 G/C cg22705602 chr4:152727874 NA -0.32 -6.16 -0.32 2.08e-9 Intelligence (multi-trait analysis); LIHC cis rs12438659 1 rs12438659 chr15:78824924 G/A cg06917634 chr15:78832804 PSMA4 -0.51 -7.27 -0.37 2.41e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs1691799 0.867 rs1168332 chr12:66761548 C/T cg16791601 chr12:66731901 HELB -0.48 -10.38 -0.49 3.87e-22 White blood cell count (basophil); LIHC cis rs1005277 0.557 rs176887 chr10:38406094 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs4555082 0.915 rs66527719 chr14:105750523 C/G cg10792982 chr14:105748885 BRF1 0.43 5.82 0.3 1.33e-8 Mean platelet volume;Platelet distribution width; LIHC cis rs1707322 0.686 rs1250 chr1:46094027 A/G cg03146154 chr1:46216737 IPP 0.57 9.79 0.47 4.11e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1577917 1.000 rs4707239 chr6:86610717 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.76 -0.39 9.97e-14 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg07424592 chr7:64974309 NA -0.8 -9.25 -0.45 2.42e-18 Diabetic kidney disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11877577 chr6:133135687 RPS12;SNORD101 -0.49 -6.23 -0.32 1.37e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2288073 0.965 rs10192600 chr2:24396680 A/G cg06627628 chr2:24431161 ITSN2 -0.57 -7.28 -0.37 2.32e-12 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs6088590 1.000 rs2076668 chr20:33437621 G/A cg06115741 chr20:33292138 TP53INP2 0.58 7.83 0.39 6.22e-14 Coronary artery disease; LIHC cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg27170947 chr2:26402098 FAM59B -0.72 -8.75 -0.43 9.8e-17 Gut microbiome composition (summer); LIHC cis rs589448 0.535 rs12423794 chr12:69713018 G/A cg22834771 chr12:69754056 YEATS4 -0.49 -8.34 -0.41 1.82e-15 Cerebrospinal fluid biomarker levels; LIHC cis rs911119 0.955 rs7270413 chr20:23593821 C/G cg16589663 chr20:23618590 CST3 0.69 6.99 0.35 1.49e-11 Chronic kidney disease; LIHC cis rs2732480 0.577 rs2634680 chr12:48734564 T/C cg21466736 chr12:48725269 NA -0.73 -11.1 -0.51 1.15e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.64e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7937682 0.883 rs1613778 chr11:111456105 G/C cg09085632 chr11:111637200 PPP2R1B -0.9 -10.84 -0.51 1.02e-23 Primary sclerosing cholangitis; LIHC cis rs6430585 0.528 rs16832205 chr2:136684632 G/A cg15123519 chr2:136567270 LCT -0.36 -5.77 -0.3 1.76e-8 Corneal structure; LIHC cis rs6061231 0.544 rs2427314 chr20:60973666 C/T cg03945807 chr20:60948434 NA 0.38 6.19 0.32 1.7e-9 Colorectal cancer; LIHC cis rs17253792 0.822 rs12100949 chr14:56040787 T/C cg01858014 chr14:56050164 KTN1 -0.7 -7.17 -0.36 4.59e-12 Putamen volume; LIHC cis rs2997447 0.761 rs61776616 chr1:26455812 C/T cg19633962 chr1:26362018 EXTL1 -0.67 -6.07 -0.31 3.37e-9 QRS complex (12-leadsum); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06684987 chr19:45567721 SFRS16 0.45 6.25 0.32 1.19e-9 Longevity; LIHC cis rs875971 0.522 rs1617484 chr7:65463095 G/A cg26939375 chr7:64535504 NA 0.45 6.99 0.35 1.48e-11 Aortic root size; LIHC cis rs2439831 0.764 rs2447193 chr15:43929733 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.98 0.35 1.56e-11 Lung cancer in ever smokers; LIHC cis rs929354 0.772 rs10228145 chr7:157007337 A/G cg17757837 chr7:157058334 UBE3C 0.75 12.46 0.56 1.19e-29 Body mass index; LIHC cis rs116248771 0.690 rs73156491 chr3:158416572 A/G cg16708174 chr3:158430962 RARRES1 0.48 6.34 0.32 7.39e-10 diarrhoeal disease at age 2; LIHC cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.9 -10.39 -0.49 3.56e-22 Platelet count; LIHC cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg12310025 chr6:25882481 NA -0.63 -8.89 -0.43 3.66e-17 Blood metabolite levels; LIHC cis rs1843834 0.505 rs2140508 chr2:225355839 G/T cg22509189 chr2:225307070 NA -0.81 -11.56 -0.53 2.51e-26 IgE levels in asthmatics (D.p. specific); LIHC cis rs2549003 0.966 rs10213701 chr5:131824064 T/A cg02551604 chr5:131831745 NA -0.5 -7.47 -0.37 6.74e-13 Asthma (sex interaction); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20760063 chr17:41277580 NBR2;BRCA1 -0.57 -7.4 -0.37 1.06e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs11711311 1.000 rs12497716 chr3:113453258 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.25 0.41 3.56e-15 IgG glycosylation; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg21914477 chr6:5067092 NA 0.38 6.6 0.34 1.59e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs1865721 1.000 rs72977890 chr18:73198776 C/A cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.16e-13 Intelligence; LIHC trans rs2243480 1.000 rs6958289 chr7:65657111 T/G cg10756647 chr7:56101905 PSPH -1.07 -13.13 -0.58 3.48e-32 Diabetic kidney disease; LIHC cis rs72627123 0.656 rs4646864 chr14:74526703 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.88 8.7 0.43 1.38e-16 Morning vs. evening chronotype; LIHC cis rs11031096 0.589 rs935130 chr11:4213530 A/G cg18678763 chr11:4115507 RRM1 -0.42 -6.25 -0.32 1.2e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs60752752 0.852 rs58127527 chr1:153370085 G/T cg14901121 chr8:98817630 LAPTM4B -0.43 -7.17 -0.36 4.6e-12 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg04317338 chr11:64019027 PLCB3 0.77 9.63 0.46 1.39e-19 Mean platelet volume; LIHC cis rs2573652 0.722 rs11630930 chr15:100544145 G/T cg09918751 chr15:100517450 ADAMTS17 -0.7 -12.33 -0.55 3.85e-29 Height; LIHC cis rs4908768 0.906 rs6656249 chr1:8581015 A/C cg20416874 chr1:8611966 RERE 0.56 8.88 0.43 3.9e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7772486 0.840 rs2814867 chr6:146334030 C/A cg05347473 chr6:146136440 FBXO30 0.37 6.05 0.31 3.73e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs477692 1.000 rs530466 chr10:131427717 A/G cg19680672 chr10:131412579 MGMT -0.45 -7.07 -0.36 8.69e-12 Response to temozolomide; LIHC cis rs875971 0.862 rs778707 chr7:65857027 G/A cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC cis rs13108904 0.934 rs13134106 chr4:1302902 A/G cg19318889 chr4:1322082 MAEA 0.47 6.41 0.33 4.95e-10 Obesity-related traits; LIHC cis rs6952808 0.531 rs1107351 chr7:2177093 G/A cg21782813 chr7:2030301 MAD1L1 0.37 6.32 0.32 8.01e-10 Bipolar disorder and schizophrenia; LIHC cis rs3768617 0.510 rs10737245 chr1:183100884 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs2842992 0.915 rs2758350 chr6:160118056 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.84 0.43 5.1e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs4713118 0.662 rs464312 chr6:27967591 T/A cg16479474 chr6:28041457 NA 0.43 6.65 0.34 1.15e-10 Parkinson's disease; LIHC cis rs6988985 0.530 rs3819497 chr8:143924052 C/T cg23373978 chr8:143916136 GML -0.3 -6.48 -0.33 3.23e-10 Plasma androstenedione levels in resected early stage-receptor positive breast cancer; LIHC cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg27286337 chr10:134555280 INPP5A 0.91 12.64 0.56 2.66e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3008870 0.883 rs2755249 chr1:67493662 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.35 0.66 8.35e-45 Lymphocyte percentage of white cells; LIHC cis rs172166 0.694 rs1631552 chr6:28089699 C/A cg25329415 chr6:28076851 NA 0.27 5.74 0.3 2.13e-8 Cardiac Troponin-T levels; LIHC cis rs4713118 0.513 rs156734 chr6:28007357 A/C cg16479474 chr6:28041457 NA 0.38 6.25 0.32 1.19e-9 Parkinson's disease; LIHC cis rs9303401 0.646 rs8067682 chr17:57219391 A/G cg12560992 chr17:57184187 TRIM37 0.52 7.21 0.36 3.63e-12 Cognitive test performance; LIHC cis rs7707921 0.881 rs73134739 chr5:81370760 T/C cg15871215 chr5:81402204 ATG10 -0.61 -5.95 -0.31 6.55e-9 Breast cancer; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg09033563 chr22:24373618 LOC391322 -0.48 -6.79 -0.34 4.9e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2257205 0.667 rs4453568 chr17:56934543 A/G cg12560992 chr17:57184187 TRIM37 0.67 7.22 0.36 3.29e-12 Pancreatic cancer; LIHC cis rs7267979 1.000 rs2257808 chr20:25266450 G/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs9768139 0.733 rs34173461 chr7:158122175 C/G cg06219351 chr7:158114137 PTPRN2 -0.21 -5.89 -0.3 9.01e-9 Calcium levels; LIHC cis rs7786877 0.723 rs7812235 chr7:100211486 G/C cg00334542 chr7:100209784 MOSPD3 -0.73 -7.55 -0.38 3.89e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9543976 0.925 rs2876706 chr13:76186305 T/G cg01531495 chr13:76123901 UCHL3 0.48 5.76 0.3 1.87e-8 Diabetic retinopathy; LIHC cis rs763121 0.814 rs5757212 chr22:39053757 G/C cg14440974 chr22:39074834 NA -0.35 -5.8 -0.3 1.51e-8 Menopause (age at onset); LIHC cis rs875971 0.522 rs1617484 chr7:65463095 G/A cg14393609 chr7:65229607 NA 0.39 5.83 0.3 1.3e-8 Aortic root size; LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg21747090 chr2:27597821 SNX17 -0.44 -6.55 -0.33 2.17e-10 Total body bone mineral density; LIHC cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg20011983 chr2:74347215 NA -0.39 -5.74 -0.3 2.12e-8 Gestational age at birth (maternal effect); LIHC cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg11764359 chr7:65958608 NA -0.58 -6.11 -0.31 2.67e-9 Diabetic kidney disease; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg25979624 chr1:54954752 NA 0.44 6.54 0.33 2.26e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs10751667 0.621 rs7396049 chr11:1001561 G/A ch.11.42038R chr11:967971 AP2A2 0.6 11.23 0.52 3.92e-25 Alzheimer's disease (late onset); LIHC cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg13395646 chr4:1353034 KIAA1530 -0.43 -6.31 -0.32 8.46e-10 Longevity; LIHC cis rs4148883 0.645 rs1154404 chr4:100009004 A/T cg12011299 chr4:100065546 ADH4 0.37 7.29 0.37 2.14e-12 Alcohol dependence; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg09847234 chr3:136581777 NCK1 -0.41 -6.12 -0.31 2.53e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs17125944 0.615 rs1886786 chr14:53312189 A/T cg00686598 chr14:53173677 PSMC6 -0.83 -9.96 -0.47 1.14e-20 Alzheimer's disease (late onset); LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg11494091 chr17:61959527 GH2 0.43 7.85 0.39 5.26e-14 Prudent dietary pattern; LIHC cis rs240764 0.578 rs11155613 chr6:101176642 T/C cg09795085 chr6:101329169 ASCC3 0.41 5.98 0.31 5.64e-9 Neuroticism; LIHC trans rs3942852 0.774 rs10838811 chr11:48186795 A/G cg15704280 chr7:45808275 SEPT13 -0.59 -8.03 -0.4 1.63e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs9296092 0.517 rs56069946 chr6:33511136 G/A cg13560919 chr6:33536144 NA -0.39 -6.22 -0.32 1.43e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs36051895 0.530 rs4425810 chr9:5222208 A/G cg02405213 chr9:5042618 JAK2 -0.63 -9.92 -0.47 1.46e-20 Pediatric autoimmune diseases; LIHC cis rs1669338 0.588 rs3931974 chr3:3186894 A/G cg16797762 chr3:3221439 CRBN 0.9 8.04 0.4 1.51e-14 White matter integrity; LIHC cis rs7116495 0.609 rs4387373 chr11:71774908 A/G cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.07e-17 Severe influenza A (H1N1) infection; LIHC cis rs12188164 0.543 rs7728027 chr5:459943 T/C cg08916839 chr5:415575 AHRR 0.29 6.31 0.32 8.64e-10 Cystic fibrosis severity; LIHC cis rs12765878 1.000 rs4918068 chr10:105644736 T/G cg11005552 chr10:105648138 OBFC1 0.39 6.03 0.31 4.35e-9 Coronary artery disease; LIHC trans rs1814175 0.817 rs2866863 chr11:49953242 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.08 0.36 8.34e-12 Height; LIHC cis rs1538970 0.781 rs10890330 chr1:45920406 G/A cg24296786 chr1:45957014 TESK2 -0.52 -7.49 -0.38 6.03e-13 Platelet count; LIHC cis rs909341 0.537 rs4809334 chr20:62384972 G/A cg14758556 chr20:62440591 NA 0.42 6.7 0.34 8.54e-11 Atopic dermatitis; LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg24209194 chr3:40518798 ZNF619 0.65 10.01 0.48 7.29e-21 Renal cell carcinoma; LIHC cis rs12479064 0.505 rs62153764 chr2:99818612 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.06 -12.45 -0.56 1.35e-29 Chronic sinus infection; LIHC trans rs61931739 0.534 rs11052959 chr12:33997095 T/C cg26384229 chr12:38710491 ALG10B 0.49 6.79 0.34 5.01e-11 Morning vs. evening chronotype; LIHC cis rs7584330 0.695 rs6709497 chr2:238368925 C/T cg14458575 chr2:238380390 NA 0.37 5.75 0.3 1.94e-8 Prostate cancer; LIHC cis rs7618501 0.519 rs3774750 chr3:50208406 C/G cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.49 -6.57 -0.33 1.87e-10 Intelligence (multi-trait analysis); LIHC cis rs2991971 0.967 rs10789465 chr1:45971759 T/C cg15605315 chr1:45957053 TESK2 0.49 6.9 0.35 2.55e-11 High light scatter reticulocyte count; LIHC cis rs12478296 0.901 rs58906257 chr2:243028248 T/C cg18898632 chr2:242989856 NA -0.46 -6.22 -0.32 1.42e-9 Obesity-related traits; LIHC cis rs4713118 0.629 rs149899 chr6:28019979 C/T cg16479474 chr6:28041457 NA 0.47 7.15 0.36 5.22e-12 Parkinson's disease; LIHC cis rs7100689 0.646 rs11202751 chr10:82147802 G/A cg01528321 chr10:82214614 TSPAN14 0.85 12.01 0.54 5.59e-28 Post bronchodilator FEV1; LIHC cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg09367891 chr1:107599246 PRMT6 0.68 11.07 0.51 1.56e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs79387448 0.745 rs17027430 chr2:103163237 T/C cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg07053964 chr16:624366 PIGQ -0.46 -6.47 -0.33 3.47e-10 Gut microbiome composition (summer); LIHC cis rs10078 0.571 rs890973 chr5:471494 T/C cg08916839 chr5:415575 AHRR 0.6 12.71 0.57 1.45e-30 Fat distribution (HIV); LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg18306943 chr3:40428807 ENTPD3 -0.44 -7.81 -0.39 6.94e-14 Renal cell carcinoma; LIHC cis rs10504229 0.871 rs56372514 chr8:58157166 A/G cg21724239 chr8:58056113 NA 0.44 6.09 0.31 3.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg24780086 chr5:14713043 ANKH 0.41 6.34 0.32 7.46e-10 Immature fraction of reticulocytes; LIHC cis rs12477438 0.520 rs36071868 chr2:99737120 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs3823572 0.542 rs61286514 chr7:133630693 G/A cg03336402 chr7:133662267 EXOC4 0.46 5.77 0.3 1.81e-8 Intelligence (multi-trait analysis); LIHC trans rs7618501 1.000 rs1491986 chr3:49739086 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.62 -0.34 1.35e-10 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.645 rs11040699 chr11:50023798 C/G cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs11893307 0.507 rs1465304 chr2:191585398 A/G cg05765582 chr2:191677683 NA 0.3 5.77 0.3 1.79e-8 Mean platelet volume; LIHC cis rs950776 0.518 rs4886571 chr15:78833758 G/A cg22563815 chr15:78856949 CHRNA5 -0.37 -6.76 -0.34 5.85e-11 Sudden cardiac arrest; LIHC cis rs709400 0.663 rs62007683 chr14:103894071 G/T cg26031613 chr14:104095156 KLC1 0.79 10.34 0.49 5.46e-22 Body mass index; LIHC cis rs6500602 0.893 rs4786489 chr16:4485527 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.51 0.33 2.76e-10 Schizophrenia; LIHC cis rs17401966 1.000 rs11578788 chr1:10422958 A/G cg15208524 chr1:10270712 KIF1B 0.44 6.14 0.32 2.27e-9 Hepatocellular carcinoma; LIHC cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg00149659 chr3:10157352 C3orf10 0.69 7.29 0.37 2.13e-12 Alzheimer's disease; LIHC cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg13047869 chr3:10149882 C3orf24 0.54 6.31 0.32 8.68e-10 Alzheimer's disease; LIHC cis rs12188164 0.561 rs2721010 chr5:456915 A/G cg00049323 chr5:472564 LOC25845 0.35 5.75 0.3 1.97e-8 Cystic fibrosis severity; LIHC trans rs2243480 1.000 rs4718269 chr7:65200778 C/G cg10756647 chr7:56101905 PSPH -1.08 -13.18 -0.58 2.32e-32 Diabetic kidney disease; LIHC cis rs918629 0.530 rs11744881 chr5:95240865 A/T cg10483112 chr5:95245456 ELL2 0.37 6.85 0.35 3.42e-11 IgG glycosylation; LIHC cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg10802521 chr3:52805072 NEK4 -0.45 -7.71 -0.38 1.38e-13 Bipolar disorder; LIHC cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg10360323 chr17:41437877 NA 0.4 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs8067354 0.574 rs1291947 chr17:57996336 G/T cg13753209 chr17:57696993 CLTC 0.7 10.44 0.49 2.46e-22 Hemoglobin concentration; LIHC cis rs9287719 0.674 rs11684157 chr2:10827157 C/A cg02829992 chr2:10710499 NA 0.39 6.01 0.31 4.74e-9 Prostate cancer; LIHC cis rs2153535 0.562 rs6901765 chr6:8455436 A/T cg23788917 chr6:8435910 SLC35B3 0.61 8.71 0.43 1.29e-16 Motion sickness; LIHC cis rs6570726 0.791 rs10872577 chr6:145900560 G/T cg05347473 chr6:146136440 FBXO30 0.38 5.89 0.3 9.44e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs738322 0.935 rs4384 chr22:38572440 G/C cg25457927 chr22:38595422 NA -0.28 -7.05 -0.36 9.75e-12 Cutaneous nevi; LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg13409248 chr3:40428643 ENTPD3 0.49 8.31 0.41 2.24e-15 Renal cell carcinoma; LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg11494091 chr17:61959527 GH2 0.36 6.12 0.31 2.61e-9 Height; LIHC cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs6540556 0.679 rs11808690 chr1:209891450 T/G cg05527609 chr1:210001259 C1orf107 -0.55 -7.61 -0.38 2.69e-13 Red blood cell count; LIHC cis rs10464366 0.746 rs6945547 chr7:39145389 C/G cg20302533 chr7:39170763 POU6F2 0.36 6.6 0.34 1.57e-10 IgG glycosylation; LIHC cis rs7927592 0.513 rs653056 chr11:68203625 T/C cg01657329 chr11:68192670 LRP5 -0.54 -7.93 -0.39 3.06e-14 Total body bone mineral density; LIHC cis rs4319547 0.619 rs10744208 chr12:122931559 C/A cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.41 -0.37 1.03e-12 Body mass index; LIHC cis rs7904368 0.754 rs66491181 chr10:16849430 T/C cg14835575 chr10:16859367 RSU1 0.61 8.26 0.41 3.33e-15 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs600806 0.683 rs10857789 chr1:110012293 C/T cg10127483 chr1:110009974 SYPL2 0.5 6.37 0.33 6.23e-10 Intelligence (multi-trait analysis); LIHC cis rs7020830 0.825 rs7036132 chr9:37317241 A/G cg14294708 chr9:37120828 ZCCHC7 1.16 24.69 0.8 5.28e-78 Schizophrenia; LIHC cis rs1046896 0.562 rs2380172 chr17:80887719 C/A cg02398342 chr17:80708632 TBCD;FN3K 0.39 5.96 0.31 6.12e-9 Glycated hemoglobin levels; LIHC cis rs4684776 0.867 rs1562616 chr3:11374151 C/T cg00170343 chr3:11313890 ATG7 -0.5 -6.76 -0.34 5.95e-11 Small vessel stroke; LIHC cis rs422249 0.512 rs174568 chr11:61593816 C/T cg07689907 chr11:61582574 FADS1 0.4 5.78 0.3 1.64e-8 Trans fatty acid levels; LIHC cis rs1775715 0.737 rs11008695 chr10:32216887 T/G cg14930904 chr10:32216787 ARHGAP12 0.37 6.48 0.33 3.29e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs4699052 0.963 rs6849319 chr4:104192742 G/C cg16532752 chr4:104119610 CENPE -0.4 -6.35 -0.32 6.81e-10 Testicular germ cell tumor; LIHC cis rs35306767 0.671 rs11253473 chr10:906826 A/G cg20503657 chr10:835505 NA 1.07 12.08 0.55 3.31e-28 Eosinophil percentage of granulocytes; LIHC cis rs16854884 0.657 rs6440210 chr3:143705763 A/G cg06585982 chr3:143692056 C3orf58 0.62 8.71 0.43 1.32e-16 Economic and political preferences (feminism/equality); LIHC cis rs4423214 1.000 rs12419334 chr11:71139472 T/C cg24826892 chr11:71159390 DHCR7 0.51 6.69 0.34 8.95e-11 Vitamin D levels; LIHC cis rs9560113 1.000 rs2104790 chr13:112177412 C/T cg14154082 chr13:112174009 NA 0.29 6.14 0.32 2.28e-9 Menarche (age at onset); LIHC cis rs1008375 1.000 rs6849704 chr4:17652031 G/C cg02297831 chr4:17616191 MED28 0.49 7.76 0.39 9.95e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7208859 0.623 rs9915566 chr17:29132158 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10752881 0.967 rs8179361 chr1:182974572 T/C ch.1.3577855R chr1:183094577 LAMC1 0.58 9.86 0.47 2.39e-20 Colorectal cancer; LIHC cis rs4631830 0.720 rs2611471 chr10:51503559 G/C cg20129853 chr10:51489980 NA -0.39 -8.57 -0.42 3.49e-16 Prostate-specific antigen levels; LIHC cis rs798554 0.757 rs1713919 chr7:2864706 C/A cg04166393 chr7:2884313 GNA12 0.43 5.71 0.3 2.46e-8 Height; LIHC cis rs11098699 0.848 rs11944380 chr4:124119834 T/C cg09941581 chr4:124220074 SPATA5 0.3 5.73 0.3 2.15e-8 Mosquito bite size; LIHC cis rs4742903 0.904 rs10991167 chr9:106974382 C/T cg14250997 chr9:106856677 SMC2 -0.35 -5.97 -0.31 6.1e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs67981189 0.593 rs2286311 chr14:71522955 T/C cg15816911 chr14:71606274 NA 0.42 6.79 0.34 4.98e-11 Schizophrenia; LIHC cis rs7223966 1.000 rs752621 chr17:61901880 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.6 0.34 1.58e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9534288 0.830 rs1126363 chr13:46633459 C/T cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs1355223 0.583 rs2915178 chr11:34878051 C/T cg24088639 chr11:34937564 PDHX;APIP -0.38 -6.0 -0.31 5.09e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs826838 1.000 rs1843881 chr12:38733706 A/G cg26384229 chr12:38710491 ALG10B -1.09 -15.73 -0.65 2.44e-42 Heart rate; LIHC cis rs77106637 0.858 rs117819392 chr11:72514503 C/T cg03713592 chr11:72463424 ARAP1 0.93 8.51 0.42 5.35e-16 Type 2 diabetes; LIHC cis rs10078 0.571 rs2561664 chr5:459793 T/C cg24955955 chr5:415729 AHRR 0.59 11.22 0.52 4.55e-25 Fat distribution (HIV); LIHC cis rs9640161 0.750 rs1983440 chr7:150023941 G/C cg21361702 chr7:150065534 REPIN1 0.44 5.99 0.31 5.31e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs4654899 1.000 rs6682368 chr1:21506914 G/A cg08539965 chr1:21396338 EIF4G3 0.33 5.78 0.3 1.68e-8 Superior frontal gyrus grey matter volume; LIHC cis rs7829975 0.593 rs2921061 chr8:8317615 A/T cg08975724 chr8:8085496 FLJ10661 0.56 8.67 0.42 1.73e-16 Mood instability; LIHC cis rs1865760 0.928 rs9295673 chr6:25912094 T/G cg17691542 chr6:26056736 HIST1H1C 0.41 6.08 0.31 3.16e-9 Height; LIHC cis rs561341 1.000 rs1681718 chr17:30296445 G/A cg00745463 chr17:30367425 LRRC37B -0.77 -5.71 -0.3 2.43e-8 Hip circumference adjusted for BMI; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg11494091 chr17:61959527 GH2 0.35 5.86 0.3 1.11e-8 Height; LIHC cis rs2932538 0.922 rs12750023 chr1:113118329 G/A cg22162597 chr1:113214053 CAPZA1 0.73 11.1 0.51 1.2e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs17376456 0.877 rs12716460 chr5:93416733 A/G cg25358565 chr5:93447407 FAM172A 1.13 10.32 0.49 6.66e-22 Diabetic retinopathy; LIHC cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.3 -0.45 1.65e-18 Bipolar disorder; LIHC trans rs116095464 0.558 rs62347683 chr5:230331 C/T cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs2404602 0.716 rs7164060 chr15:76707694 T/C cg23625390 chr15:77176239 SCAPER 0.36 6.0 0.31 5.07e-9 Blood metabolite levels; LIHC cis rs2576037 0.526 rs571181 chr18:44376399 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.51 -7.66 -0.38 1.87e-13 Personality dimensions; LIHC cis rs858239 0.600 rs1468592 chr7:23140647 C/T cg23682824 chr7:23144976 KLHL7 -0.43 -6.53 -0.33 2.33e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.08 0.31 3.27e-9 Menopause (age at onset); LIHC cis rs3096299 0.781 rs2170839 chr16:89409452 C/G cg06640241 chr16:89574553 SPG7 0.5 7.52 0.38 4.98e-13 Multiple myeloma (IgH translocation); LIHC cis rs6701037 0.681 rs13374887 chr1:175131962 A/T cg17845761 chr1:175162550 KIAA0040 0.41 6.93 0.35 2.06e-11 Alcohol dependence; LIHC cis rs1198430 0.639 rs2297841 chr1:23764149 C/G cg13183780 chr1:23809682 ASAP3 -0.38 -6.51 -0.33 2.63e-10 Total cholesterol levels; LIHC trans rs728616 0.681 rs12769764 chr10:81917113 C/G cg25456515 chr11:125439230 EI24 0.49 6.37 0.33 6.12e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs9916302 0.904 rs801419 chr17:37466327 A/G cg03013999 chr17:37608204 MED1 -0.35 -5.8 -0.3 1.5e-8 Glomerular filtration rate (creatinine); LIHC cis rs2204008 0.774 rs9669565 chr12:38294428 C/A cg26384229 chr12:38710491 ALG10B 0.59 8.13 0.4 7.95e-15 Bladder cancer; LIHC cis rs2304069 0.826 rs245076 chr5:149350648 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.65 8.58 0.42 3.37e-16 HIV-1 control; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01252513 chr12:111758092 CUX2 0.43 6.04 0.31 4.12e-9 Longevity; LIHC cis rs1707322 0.682 rs10890335 chr1:46100394 G/C cg03146154 chr1:46216737 IPP 0.56 9.52 0.46 3.31e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 1.000 rs9841335 chr3:40475858 G/A cg09455208 chr3:40491958 NA 0.36 7.4 0.37 1.09e-12 Renal cell carcinoma; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg00800038 chr16:89945340 TCF25 -0.66 -10.35 -0.49 5.25e-22 Skin colour saturation; LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs2842992 0.692 rs1128661 chr6:160211554 T/G cg11366901 chr6:160182831 ACAT2 0.86 14.38 0.61 5.22e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs67478160 0.619 rs2368560 chr14:104273311 C/T cg08213375 chr14:104286397 PPP1R13B 0.64 12.25 0.55 7.31e-29 Schizophrenia; LIHC cis rs4423214 0.547 rs11234030 chr11:71236967 G/A cg05163923 chr11:71159392 DHCR7 -0.59 -7.24 -0.36 3.05e-12 Vitamin D levels; LIHC cis rs9309473 0.950 rs7567585 chr2:73751966 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.95 -0.35 1.87e-11 Metabolite levels; LIHC cis rs611744 0.934 rs672408 chr8:109224390 A/G cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs9354308 1.000 rs9342503 chr6:66565436 A/G cg07460842 chr6:66804631 NA -0.53 -6.31 -0.32 8.5e-10 Metabolite levels; LIHC cis rs16912285 0.591 rs12794505 chr11:24364195 A/G ch.11.24196551F chr11:24239977 NA -0.67 -8.14 -0.4 7.44e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg13047869 chr3:10149882 C3orf24 0.48 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs4906332 0.933 rs35999760 chr14:103924481 A/C cg04998671 chr14:104000505 TRMT61A -0.45 -6.18 -0.32 1.86e-9 Coronary artery disease; LIHC cis rs9309473 0.898 rs9807961 chr2:73694043 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.75 -0.34 6.18e-11 Metabolite levels; LIHC cis rs921968 0.643 rs471846 chr2:219432237 C/T cg02985541 chr2:219472218 PLCD4 0.44 8.35 0.41 1.7e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs651907 0.557 rs3864012 chr3:101397623 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.7 11.79 0.54 3.8e-27 Colorectal cancer; LIHC trans rs9929218 1.000 rs13330350 chr16:68800849 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.78 -0.43 8.25e-17 Colorectal cancer; LIHC cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg17971929 chr21:40555470 PSMG1 0.84 10.04 0.48 5.69e-21 Cognitive function; LIHC cis rs7909074 1.000 rs6593447 chr10:45400235 G/A cg05187965 chr10:45406764 TMEM72 -0.27 -6.85 -0.35 3.51e-11 Mean corpuscular volume; LIHC cis rs3862260 0.905 rs3850870 chr1:120161037 C/T cg11530693 chr1:120165357 ZNF697 0.47 7.53 0.38 4.59e-13 Systemic lupus erythematosus; LIHC cis rs11098499 0.954 rs9685777 chr4:120365965 C/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg09904177 chr6:26538194 HMGN4 0.57 11.28 0.52 2.58e-25 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.739 rs2758846 chr6:86349570 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.32 -0.55 4.13e-29 Response to antipsychotic treatment; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05920998 chr6:656504 HUS1B;EXOC2 0.39 6.27 0.32 1.07e-9 Longevity; LIHC cis rs11098499 0.863 rs1155576 chr4:120450159 A/C cg09307838 chr4:120376055 NA 0.76 11.6 0.53 1.88e-26 Corneal astigmatism; LIHC cis rs10791097 0.694 rs7942621 chr11:130751308 C/G cg09137382 chr11:130731461 NA 0.42 6.26 0.32 1.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs992157 0.730 rs4280446 chr2:219184721 T/C cg00012203 chr2:219082015 ARPC2 0.76 10.74 0.5 2.16e-23 Colorectal cancer; LIHC cis rs11792861 0.962 rs72607162 chr9:111793719 T/C cg05043794 chr9:111880884 C9orf5 -0.3 -7.01 -0.35 1.3e-11 Menarche (age at onset); LIHC cis rs11122272 0.735 rs2790893 chr1:231508976 T/G cg06096015 chr1:231504339 EGLN1 0.51 9.27 0.45 2.12e-18 Hemoglobin concentration; LIHC cis rs2153535 0.580 rs1034272 chr6:8469335 G/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs7131987 0.650 rs11050188 chr12:29473108 A/C cg14222432 chr12:29376421 FAR2 0.37 7.02 0.35 1.2e-11 QT interval; LIHC cis rs2075371 0.835 rs1646724 chr7:134001875 T/G cg11752832 chr7:134001865 SLC35B4 0.49 7.3 0.37 1.99e-12 Mean platelet volume; LIHC cis rs7772486 0.875 rs6570736 chr6:146388320 C/T cg23711669 chr6:146136114 FBXO30 0.59 10.15 0.48 2.57e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs7412746 0.553 rs59337856 chr1:150746406 G/T cg18016565 chr1:150552671 MCL1 0.54 10.13 0.48 2.88e-21 Melanoma; LIHC cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg08888203 chr3:10149979 C3orf24 0.59 6.75 0.34 6.28e-11 Alzheimer's disease; LIHC cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg18357526 chr6:26021779 HIST1H4A 0.52 7.54 0.38 4.18e-13 Blood metabolite levels; LIHC cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg26818010 chr10:134567672 INPP5A -0.8 -9.8 -0.47 3.9e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2274273 0.870 rs10139000 chr14:55849876 G/T cg01864836 chr14:55583639 NA -0.38 -6.7 -0.34 8.76e-11 Protein biomarker; LIHC trans rs6938574 0.672 rs6569520 chr6:128365034 C/G cg01500097 chr6:110011156 AKD1;FIG4 -0.4 -6.71 -0.34 8.07e-11 Menarche (age at onset); LIHC cis rs9527 0.830 rs3740392 chr10:104636855 T/C cg04362960 chr10:104952993 NT5C2 0.43 5.82 0.3 1.37e-8 Arsenic metabolism; LIHC cis rs8103278 0.507 rs522769 chr19:46284520 G/A cg11657440 chr19:46296263 DMWD 0.68 12.6 0.56 3.72e-30 Coronary artery disease; LIHC cis rs7786877 0.723 rs7812123 chr7:100211556 C/A cg00334542 chr7:100209784 MOSPD3 -0.73 -7.55 -0.38 3.89e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10911232 0.507 rs10911230 chr1:183051118 A/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Hypertriglyceridemia; LIHC cis rs12479064 0.671 rs62155807 chr2:100076579 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.7 -8.47 -0.42 7.4e-16 Chronic sinus infection; LIHC cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg06481639 chr22:41940642 POLR3H -0.74 -7.36 -0.37 1.41e-12 Vitiligo; LIHC cis rs950776 0.518 rs12594391 chr15:78816240 A/G cg06917634 chr15:78832804 PSMA4 0.93 14.06 0.61 9.61e-36 Sudden cardiac arrest; LIHC cis rs7772486 0.597 rs9285508 chr6:146262697 G/T cg23711669 chr6:146136114 FBXO30 -0.64 -9.17 -0.44 4.57e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg02951883 chr7:2050386 MAD1L1 -0.76 -13.03 -0.58 8.59e-32 Bipolar disorder and schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20390150 chr22:43547555 TSPO -0.44 -6.56 -0.33 1.94e-10 Cognitive function; LIHC cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.69 9.52 0.46 3.23e-19 Alzheimer's disease; LIHC cis rs2637266 0.655 rs10824436 chr10:78457848 T/C cg18941641 chr10:78392320 NA 0.27 5.73 0.3 2.2e-8 Pulmonary function; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg07133347 chr1:107600762 PRMT6 -0.41 -5.75 -0.3 1.96e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9590974 0.796 rs1773128 chr13:47225440 T/A cg04092803 chr13:47240378 LRCH1 0.29 5.95 0.31 6.47e-9 PR segment; LIHC cis rs7071206 0.947 rs4979905 chr10:79416367 C/T cg07817648 chr10:79422355 NA -0.35 -7.04 -0.36 1.06e-11 Bone mineral density; LIHC cis rs67311347 0.549 rs60249586 chr3:40246659 G/A cg13409248 chr3:40428643 ENTPD3 0.39 6.15 0.32 2.18e-9 Renal cell carcinoma; LIHC cis rs4820294 0.669 rs35662099 chr22:38053909 C/T cg00142150 chr22:38071001 LGALS1 0.44 7.58 0.38 3.38e-13 Fat distribution (HIV); LIHC cis rs7727544 0.735 rs272884 chr5:131668654 G/C cg24060327 chr5:131705240 SLC22A5 -0.59 -8.44 -0.42 9.19e-16 Blood metabolite levels; LIHC cis rs9640161 0.742 rs2108854 chr7:150017408 C/T cg21361702 chr7:150065534 REPIN1 -0.45 -6.27 -0.32 1.09e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs4268898 0.697 rs10445892 chr2:24406958 T/C cg06627628 chr2:24431161 ITSN2 0.44 6.27 0.32 1.06e-9 Asthma; LIHC cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs801193 1.000 rs7783924 chr7:66209057 A/C cg14393609 chr7:65229607 NA 0.37 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs17826219 0.636 rs79565452 chr17:29142841 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Body mass index; LIHC cis rs6964587 0.621 rs39744 chr7:92043016 A/G cg17063962 chr7:91808500 NA 0.64 10.76 0.5 1.83e-23 Breast cancer; LIHC cis rs57590327 0.555 rs2053805 chr3:81738414 T/C cg07356753 chr3:81810745 GBE1 -0.54 -8.29 -0.41 2.6e-15 Extraversion; LIHC cis rs2851682 0.706 rs2072113 chr11:61604967 C/T cg27386326 chr11:61587980 NA 0.56 8.96 0.44 2.15e-17 Gestational age at birth (child effect);Trans fatty acid levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg21507487 chr14:71941057 NA -0.29 -6.39 -0.33 5.45e-10 Calcium levels; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.46e-8 Menopause (age at onset); LIHC cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg24431193 chr11:63883947 FLRT1;MACROD1 -0.4 -5.96 -0.31 6.15e-9 Platelet count; LIHC cis rs769267 0.825 rs1469713 chr19:19528806 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.07 0.4 1.17e-14 Tonsillectomy; LIHC cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.33 0.41 1.99e-15 Platelet count; LIHC cis rs8177253 0.828 rs8177259 chr3:133480388 T/C cg12373951 chr3:133503437 NA 0.69 12.44 0.56 1.41e-29 Iron status biomarkers; LIHC trans rs11098499 0.657 rs4463052 chr4:120313258 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg25364880 chr3:44379878 C3orf23 0.55 7.49 0.38 5.82e-13 Depressive symptoms; LIHC cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg05564831 chr3:52568323 NT5DC2 0.35 5.83 0.3 1.27e-8 Bipolar disorder; LIHC cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs7959452 0.570 rs10878964 chr12:69720691 T/G cg20891283 chr12:69753455 YEATS4 0.8 15.25 0.64 2.02e-40 Blood protein levels; LIHC cis rs9916302 0.595 rs4795371 chr17:37636695 T/G cg00129232 chr17:37814104 STARD3 -0.44 -6.97 -0.35 1.63e-11 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg02359409 chr6:42947317 PEX6 -0.48 -6.79 -0.34 5.03e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg13903179 chr13:21900392 NA 0.33 5.82 0.3 1.36e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs1401999 1.000 rs2176824 chr3:183654029 C/G cg01324343 chr3:183735012 ABCC5 0.74 12.12 0.55 2.27e-28 Anterior chamber depth; LIHC cis rs7903847 0.596 rs10786340 chr10:99156563 G/C cg08345082 chr10:99160200 RRP12 -0.39 -6.58 -0.34 1.81e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1403694 0.695 rs1851665 chr3:186436398 A/G cg12454167 chr3:186435060 KNG1 0.38 8.73 0.43 1.11e-16 Blood protein levels; LIHC cis rs9393777 0.513 rs9379895 chr6:26592707 A/G cg12826209 chr6:26865740 GUSBL1 0.55 6.27 0.32 1.1e-9 Intelligence (multi-trait analysis); LIHC cis rs2645694 0.626 rs2645708 chr4:77822682 G/A cg06046430 chr4:77819534 ANKRD56 0.49 6.52 0.33 2.59e-10 Emphysema distribution in smoking; LIHC cis rs6960043 0.689 rs12538003 chr7:15058692 G/A cg19272540 chr7:15055459 NA 0.25 6.42 0.33 4.58e-10 Type 2 diabetes; LIHC cis rs7246865 0.859 rs16981598 chr19:17204327 A/G cg16202187 chr19:17186497 HAUS8;MYO9B 0.4 5.9 0.3 8.69e-9 Reticulocyte fraction of red cells; LIHC cis rs4975616 0.804 rs459961 chr5:1337106 T/A cg06550200 chr5:1325588 CLPTM1L -0.68 -10.71 -0.5 2.79e-23 Lung cancer; LIHC cis rs7715806 0.500 rs72633985 chr5:75006384 A/G cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6788895 1.000 rs16862858 chr3:150529952 C/T cg09723797 chr3:150481914 SIAH2 -0.54 -6.44 -0.33 3.94e-10 Breast cancer; LIHC cis rs941408 0.515 rs1640265 chr19:2784405 C/T cg02580895 chr19:2754563 NA -0.45 -6.41 -0.33 4.94e-10 Total cholesterol levels; LIHC cis rs6539267 0.741 rs7314289 chr12:106686260 A/C cg00173435 chr12:106696525 TCP11L2 0.6 8.06 0.4 1.27e-14 Tourette syndrome; LIHC cis rs6582630 0.519 rs4406888 chr12:38293312 A/C cg26384229 chr12:38710491 ALG10B 0.59 8.13 0.4 7.95e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs6840360 0.571 rs2165789 chr4:152510130 A/T cg22705602 chr4:152727874 NA -0.32 -6.13 -0.31 2.38e-9 Intelligence (multi-trait analysis); LIHC cis rs9309473 0.948 rs2421550 chr2:73658686 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -7.05 -0.36 9.96e-12 Metabolite levels; LIHC cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -10.04 -0.48 5.91e-21 Platelet count; LIHC cis rs10791097 0.728 rs10894265 chr11:130714613 T/C cg12179176 chr11:130786555 SNX19 -0.62 -9.1 -0.44 7.43e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs208520 1.000 rs72884033 chr6:66995747 T/C cg07460842 chr6:66804631 NA 0.68 7.38 0.37 1.22e-12 Exhaled nitric oxide output; LIHC cis rs7044106 0.762 rs4837789 chr9:123426256 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.39 0.52 1.08e-25 Hip circumference adjusted for BMI; LIHC cis rs288342 0.797 rs288313 chr2:183649154 C/T cg02625481 chr2:183667124 NA -0.29 -6.09 -0.31 2.98e-9 Recurrent major depressive disorder; LIHC cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg16423285 chr20:60520624 NA -0.53 -8.68 -0.42 1.65e-16 Obesity-related traits; LIHC cis rs1775715 0.835 rs113450267 chr10:32223728 G/A cg14930904 chr10:32216787 ARHGAP12 0.38 6.74 0.34 6.74e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs11628318 0.515 rs1190334 chr14:103112591 T/C cg12046867 chr14:103022105 NA 0.39 5.97 0.31 5.94e-9 Platelet count; LIHC cis rs796364 0.806 rs10931890 chr2:201102055 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.94 -0.35 2.03e-11 Schizophrenia; LIHC cis rs748404 0.660 rs2467738 chr15:43739936 T/A cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.95 0.4 2.65e-14 Lung cancer; LIHC cis rs4423214 1.000 rs11600569 chr11:71173747 C/G cg24826892 chr11:71159390 DHCR7 0.5 6.42 0.33 4.65e-10 Vitamin D levels; LIHC cis rs34779708 0.931 rs55724039 chr10:35465397 A/G cg03585969 chr10:35415529 CREM 0.87 13.11 0.58 4.23e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2637266 0.935 rs2583059 chr10:78395178 G/C cg18941641 chr10:78392320 NA 0.29 6.4 0.33 5.23e-10 Pulmonary function; LIHC cis rs1878918 0.967 rs10103022 chr8:32325630 A/G cg16623836 chr8:32453385 NRG1 0.33 5.73 0.3 2.22e-8 Cleft lip with or without cleft palate; LIHC cis rs4843747 0.671 rs72818540 chr16:88078988 C/T cg07560587 chr16:88016574 BANP 0.38 5.92 0.3 7.95e-9 Menopause (age at onset); LIHC cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg23149560 chr2:74406255 MOBKL1B 0.44 6.18 0.32 1.83e-9 Gestational age at birth (maternal effect); LIHC cis rs933688 1.000 rs985434 chr5:90744509 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.35 0.72 6.94e-57 Smoking behavior; LIHC cis rs7208859 0.623 rs9906957 chr17:29157755 C/T cg13385521 chr17:29058706 SUZ12P 0.81 7.84 0.39 5.67e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7829975 0.593 rs2921061 chr8:8317615 A/T cg14343924 chr8:8086146 FLJ10661 0.51 6.46 0.33 3.69e-10 Mood instability; LIHC cis rs35110281 0.506 rs13051661 chr21:45111518 A/T cg21573476 chr21:45109991 RRP1B -0.59 -11.13 -0.52 9.11e-25 Mean corpuscular volume; LIHC cis rs3762637 1.000 rs6790051 chr3:122192846 T/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg05484376 chr2:27715224 FNDC4 0.36 6.16 0.32 2.07e-9 Total body bone mineral density; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg12419862 chr22:24373484 LOC391322 -0.68 -10.47 -0.49 1.91e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12249377 0.519 rs11599902 chr10:92598823 A/G cg14313238 chr10:92632228 RPP30 0.37 6.17 0.32 1.89e-9 White matter microstructure (global fractional anisotropy); LIHC trans rs801193 1.000 rs7782320 chr7:66177098 C/T cg26939375 chr7:64535504 NA 0.41 6.64 0.34 1.26e-10 Aortic root size; LIHC cis rs589448 0.867 rs623853 chr12:69753830 G/A cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 1.02e-20 Cerebrospinal fluid biomarker levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23099349 chr6:26032281 HIST1H3B 0.47 7.11 0.36 6.81e-12 Pancreatic cancer; LIHC cis rs1997103 1.000 rs9649781 chr7:55411809 A/G cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7296418 0.699 rs1109559 chr12:123757861 C/T cg00376283 chr12:123451042 ABCB9 0.63 10.35 0.49 5.26e-22 Platelet count; LIHC cis rs826838 0.586 rs10785554 chr12:38628749 T/A cg26384229 chr12:38710491 ALG10B 0.42 6.41 0.33 4.94e-10 Heart rate; LIHC cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.36 -0.37 1.35e-12 Bipolar disorder; LIHC cis rs9911578 0.967 rs2611781 chr17:56703124 C/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.87 -0.43 4.18e-17 Intelligence (multi-trait analysis); LIHC cis rs11628318 0.614 rs3825565 chr14:103060465 G/A cg01864069 chr14:103024347 NA -0.47 -7.45 -0.37 7.91e-13 Platelet count; LIHC cis rs11031096 0.678 rs10767872 chr11:4184239 T/G cg18678763 chr11:4115507 RRM1 -0.43 -6.15 -0.32 2.13e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs17376456 1.000 rs13163610 chr5:93548877 A/C cg25358565 chr5:93447407 FAM172A 1.08 9.8 0.47 3.72e-20 Diabetic retinopathy; LIHC trans rs1728785 0.901 rs1170444 chr16:68573287 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.82e-9 Ulcerative colitis; LIHC trans rs2727020 0.521 rs10839299 chr11:49573981 C/T cg15704280 chr7:45808275 SEPT13 -0.8 -12.07 -0.55 3.42e-28 Coronary artery disease; LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg18306943 chr3:40428807 ENTPD3 0.43 7.53 0.38 4.67e-13 Renal cell carcinoma; LIHC trans rs916888 0.821 rs70602 chr17:44859715 T/C cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7619427 0.908 rs62254360 chr3:44082313 G/A cg24966902 chr3:44043705 NA 0.43 6.16 0.32 2.08e-9 Schizophrenia; LIHC cis rs11123170 0.640 rs931472 chr2:113969948 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.53 -6.79 -0.34 5e-11 Renal function-related traits (BUN); LIHC cis rs7618501 0.699 rs2681780 chr3:49897830 C/T cg24110177 chr3:50126178 RBM5 -0.53 -8.22 -0.41 4.25e-15 Intelligence (multi-trait analysis); LIHC cis rs921968 0.541 rs733925 chr2:219302466 G/A cg02176678 chr2:219576539 TTLL4 -0.56 -7.77 -0.39 9.01e-14 Mean corpuscular hemoglobin concentration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08450409 chr12:53342662 KRT18 0.46 6.75 0.34 6.3e-11 Cognitive function; LIHC cis rs11971779 0.553 rs36002669 chr7:139113161 T/A cg07862535 chr7:139043722 LUC7L2 0.59 10.21 0.48 1.51e-21 Diisocyanate-induced asthma; LIHC cis rs754466 0.580 rs1866437 chr10:79526766 A/G cg17075019 chr10:79541650 NA -0.73 -10.61 -0.5 6.22e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs2243480 1.000 rs1499614 chr7:65730798 A/T cg10756647 chr7:56101905 PSPH 1.03 12.52 0.56 7.58e-30 Diabetic kidney disease; LIHC cis rs6570726 0.599 rs455001 chr6:145854450 A/T cg23711669 chr6:146136114 FBXO30 0.64 9.84 0.47 2.86e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.51 0.46 3.45e-19 Electroencephalogram traits; LIHC cis rs2953145 0.545 rs2975751 chr2:241521135 G/A cg07929629 chr2:241523174 NA 0.64 9.39 0.45 8.67e-19 Bipolar disorder; LIHC cis rs908922 0.605 rs3753448 chr1:152486407 A/C cg20991723 chr1:152506922 NA 0.49 8.34 0.41 1.78e-15 Hair morphology; LIHC cis rs7520050 0.966 rs12144263 chr1:46352446 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 5.97 0.31 5.8e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg11764359 chr7:65958608 NA -0.57 -5.92 -0.31 7.72e-9 Diabetic kidney disease; LIHC cis rs600806 0.815 rs4970754 chr1:109969721 A/G cg23091122 chr1:110024289 SYPL2 -0.49 -6.46 -0.33 3.63e-10 Intelligence (multi-trait analysis); LIHC trans rs35110281 0.811 rs4819264 chr21:45017349 G/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.13 0.31 2.39e-9 Mean corpuscular volume; LIHC cis rs7944584 0.551 rs12224672 chr11:47500400 C/T cg20307385 chr11:47447363 PSMC3 0.89 12.45 0.56 1.3e-29 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2354432 0.607 rs72692962 chr1:146802674 C/A cg25205988 chr1:146714368 CHD1L -0.9 -10.85 -0.51 8.86e-24 Mitochondrial DNA levels; LIHC cis rs6701037 0.681 rs6664840 chr1:175128726 A/G cg17845761 chr1:175162550 KIAA0040 -0.43 -7.15 -0.36 5.35e-12 Alcohol dependence; LIHC cis rs4243830 1.000 rs41278016 chr1:6584045 C/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.86 7.9 0.39 3.83e-14 Body mass index; LIHC cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg06453172 chr10:134556979 INPP5A -0.62 -7.77 -0.39 9.51e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg15236063 chr3:53919558 SELK 0.43 6.09 0.31 2.98e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12477438 0.520 rs11123763 chr2:99750673 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.82 0.65 1.12e-42 Chronic sinus infection; LIHC cis rs703842 1.000 rs10747783 chr12:58176614 T/C cg18357645 chr12:58087776 OS9 -0.44 -6.9 -0.35 2.48e-11 Multiple sclerosis; LIHC cis rs12220238 1.000 rs10762582 chr10:75968316 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.22 0.32 1.47e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs798554 0.797 rs798488 chr7:2802522 T/C cg13628971 chr7:2884303 GNA12 0.53 7.76 0.39 9.95e-14 Height; LIHC cis rs10871290 0.881 rs3863439 chr16:74470644 T/C cg01733217 chr16:74700730 RFWD3 -0.44 -7.49 -0.38 6.07e-13 Breast cancer; LIHC cis rs17106184 0.786 rs72898974 chr1:50975971 C/T cg07174182 chr1:51127561 FAF1 -0.7 -7.19 -0.36 4.12e-12 Type 2 diabetes; LIHC cis rs10751667 0.621 rs7396049 chr11:1001561 G/A cg06064525 chr11:970664 AP2A2 -0.44 -10.63 -0.5 5.51e-23 Alzheimer's disease (late onset); LIHC trans rs7618501 1.000 rs3749240 chr3:49750188 T/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC cis rs9325144 0.647 rs11169258 chr12:39113040 C/T cg26384229 chr12:38710491 ALG10B -0.43 -6.11 -0.31 2.75e-9 Morning vs. evening chronotype; LIHC cis rs12477438 0.501 rs11688004 chr2:99735052 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.6 11.19 0.52 5.77e-25 Chronic sinus infection; LIHC cis rs7131987 0.903 rs11050161 chr12:29420049 A/G cg16970926 chr12:29381810 FAR2 0.29 5.97 0.31 5.96e-9 QT interval; LIHC cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 11.86 0.54 2.09e-27 Platelet count; LIHC cis rs861020 0.527 rs614662 chr1:209962419 C/T cg04352962 chr1:209979756 IRF6 -0.36 -5.72 -0.3 2.36e-8 Orofacial clefts; LIHC cis rs11792861 0.926 rs76689835 chr9:111833792 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 8.86 0.43 4.34e-17 Menarche (age at onset); LIHC cis rs116095464 0.558 rs10055405 chr5:265666 C/T cg22857025 chr5:266934 NA -1.52 -18.8 -0.71 1.22e-54 Breast cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg12990219 chr3:17686199 TBC1D5 -0.28 -6.31 -0.32 8.75e-10 Calcium levels; LIHC cis rs4853012 0.838 rs2177707 chr2:74356850 A/G cg20891558 chr2:74357851 NA 0.82 16.87 0.67 6.88e-47 Gestational age at birth (maternal effect); LIHC cis rs72781680 0.848 rs72798057 chr2:23976731 T/C cg08917208 chr2:24149416 ATAD2B 0.82 7.41 0.37 1.01e-12 Lymphocyte counts; LIHC cis rs10870270 1.000 rs11146338 chr10:133770291 C/G cg26149184 chr10:133730230 NA 0.47 7.49 0.38 5.75e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6840360 0.555 rs4554052 chr4:152726610 T/C cg22705602 chr4:152727874 NA 0.39 8.33 0.41 1.95e-15 Intelligence (multi-trait analysis); LIHC cis rs4523957 0.928 rs8065650 chr17:2180823 A/G cg16513277 chr17:2031491 SMG6 0.51 8.23 0.41 4.06e-15 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs11098499 0.779 rs10011097 chr4:120310359 T/G cg25214090 chr10:38739885 LOC399744 0.55 8.68 0.42 1.65e-16 Corneal astigmatism; LIHC cis rs8103278 1.000 rs9676288 chr19:46292060 G/T cg02376097 chr19:46275166 DMPK -0.44 -6.74 -0.34 6.58e-11 Coronary artery disease; LIHC cis rs611744 0.967 rs602384 chr8:109188185 G/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs2075371 0.871 rs418135 chr7:133949898 A/G cg20476274 chr7:133979776 SLC35B4 0.71 11.77 0.54 4.45e-27 Mean platelet volume; LIHC cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.42 7.03 0.36 1.1e-11 Height; LIHC cis rs597539 0.652 rs622082 chr11:68703959 A/G cg06028808 chr11:68637592 NA 0.45 5.77 0.3 1.79e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7647973 0.769 rs7434187 chr3:49032967 C/T cg20833759 chr3:49053208 WDR6;DALRD3 0.54 6.33 0.32 7.51e-10 Menarche (age at onset); LIHC trans rs208520 0.690 rs7739253 chr6:66861052 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.34 -0.41 1.81e-15 Exhaled nitric oxide output; LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg06873352 chr17:61820015 STRADA 0.55 8.48 0.42 6.68e-16 Height; LIHC cis rs9768139 0.733 rs921617 chr7:158118198 A/G cg25566285 chr7:158114605 PTPRN2 0.22 6.07 0.31 3.42e-9 Calcium levels; LIHC cis rs1577917 0.958 rs13207173 chr6:86457522 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.35 -0.41 1.7e-15 Response to antipsychotic treatment; LIHC cis rs11098499 0.954 rs17005535 chr4:120411562 C/T cg09307838 chr4:120376055 NA 0.77 12.52 0.56 7.22e-30 Corneal astigmatism; LIHC cis rs561341 0.660 rs7406043 chr17:30220152 C/G cg13647721 chr17:30228624 UTP6 0.8 7.74 0.39 1.17e-13 Hip circumference adjusted for BMI; LIHC cis rs10540 1.000 rs117339389 chr11:505025 T/A cg03352830 chr11:487213 PTDSS2 0.78 6.56 0.33 2.03e-10 Body mass index; LIHC cis rs9303401 0.659 rs36109237 chr17:56653834 A/G cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19462847 chr11:6633911 TAF10 0.51 7.28 0.37 2.26e-12 Pancreatic cancer; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg04234412 chr22:24373322 LOC391322 -0.69 -10.27 -0.49 9.5e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1552244 0.882 rs61429272 chr3:10037320 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs6120849 0.707 rs6088703 chr20:33676049 T/A cg24642439 chr20:33292090 TP53INP2 0.66 7.14 0.36 5.8e-12 Protein C levels; LIHC cis rs9611519 0.620 rs9607782 chr22:41587556 T/A cg03806693 chr22:41940476 POLR3H -0.69 -7.34 -0.37 1.52e-12 Neuroticism; LIHC cis rs1494373 0.509 rs12032280 chr1:220873363 C/T cg06786860 chr1:220876396 NA -0.44 -6.34 -0.32 7.46e-10 Response to antipsychotic therapy (extrapyramidal side effects); LIHC cis rs600806 0.745 rs4970763 chr1:110006349 G/A cg11161837 chr1:110010384 SYPL2 0.45 6.06 0.31 3.51e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg18306943 chr3:40428807 ENTPD3 -0.43 -7.57 -0.38 3.56e-13 Renal cell carcinoma; LIHC cis rs807669 0.903 rs1780640 chr22:19174597 C/T cg02655711 chr22:19163373 SLC25A1 0.72 11.14 0.52 8.54e-25 Metabolite levels; LIHC cis rs7085104 0.727 rs12773892 chr10:104631177 G/T cg04362960 chr10:104952993 NT5C2 0.57 6.85 0.35 3.55e-11 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs2832191 0.632 rs1984011 chr21:30337831 T/A cg08807101 chr21:30365312 RNF160 -0.79 -11.69 -0.53 9e-27 Dental caries; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg05063087 chr10:102133314 C10orf75 0.44 6.26 0.32 1.18e-9 Migraine with aura; LIHC cis rs11212260 0.655 rs79317540 chr11:107285785 T/C cg25435332 chr11:107328525 CWF19L2 0.8 8.47 0.42 7.45e-16 IgG glycosylation; LIHC cis rs2153535 0.601 rs718504 chr6:8527512 A/G cg23788917 chr6:8435910 SLC35B3 0.63 9.02 0.44 1.37e-17 Motion sickness; LIHC cis rs6504663 0.558 rs11871603 chr17:48559037 T/G cg00901687 chr17:48585270 MYCBPAP 0.45 6.33 0.32 7.63e-10 Visceral fat; LIHC cis rs986417 0.688 rs6573321 chr14:61101710 A/G cg27398547 chr14:60952738 C14orf39 0.66 7.32 0.37 1.81e-12 Gut microbiota (bacterial taxa); LIHC cis rs6882046 0.513 rs194225 chr5:88001186 A/G cg22951263 chr5:87985283 NA -0.42 -7.37 -0.37 1.26e-12 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs1048238 0.548 rs848217 chr1:16272250 A/G cg21385522 chr1:16154831 NA -0.47 -7.72 -0.39 1.28e-13 Systolic blood pressure; LIHC cis rs7635838 0.687 rs9849485 chr3:11395741 G/A cg00170343 chr3:11313890 ATG7 0.56 9.25 0.45 2.52e-18 HDL cholesterol; LIHC cis rs8072100 1.000 rs4794016 chr17:45725931 T/A cg08085267 chr17:45401833 C17orf57 0.57 8.52 0.42 5.28e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7903847 0.667 rs7096801 chr10:99140969 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs3106136 0.967 rs61004493 chr4:95163317 T/C cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.11 -0.4 9.46e-15 Capecitabine sensitivity; LIHC cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg16822855 chr3:40428330 ENTPD3 0.33 6.07 0.31 3.32e-9 Renal cell carcinoma; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg01339444 chr6:118972232 C6orf204 0.59 5.93 0.31 7.53e-9 Diastolic blood pressure; LIHC cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.8 -0.57 6.21e-31 Alzheimer's disease; LIHC cis rs7618915 0.547 rs11714419 chr3:52628816 A/G cg18404041 chr3:52824283 ITIH1 -0.55 -8.92 -0.43 2.9e-17 Bipolar disorder; LIHC cis rs2760061 0.626 rs672977 chr1:228120288 A/C cg01200585 chr1:228362443 C1orf69 -0.39 -5.85 -0.3 1.17e-8 Diastolic blood pressure; LIHC cis rs9457247 0.935 rs2757050 chr6:167377165 G/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.85 -0.47 2.62e-20 Crohn's disease; LIHC cis rs12479064 0.724 rs3087403 chr2:100058870 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -6.79 -0.34 5.04e-11 Chronic sinus infection; LIHC cis rs16828019 0.852 rs71648535 chr1:41613750 G/A cg03962019 chr1:41807865 NA 0.53 7.51 0.38 5.27e-13 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.665 rs4304137 chr6:86217448 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.47 8.33 0.41 2.01e-15 Response to antipsychotic treatment; LIHC cis rs3808502 0.527 rs2736374 chr8:11113828 A/G cg17371911 chr8:10683139 PINX1;MIR1322 0.5 6.3 0.32 8.9e-10 Neuroticism; LIHC cis rs7607369 0.719 rs12613545 chr2:219623504 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7224314 1.000 rs7221926 chr17:65352181 A/T cg01507342 chr17:65387096 PITPNC1 -0.46 -6.04 -0.31 3.98e-9 Diisocyanate-induced asthma; LIHC cis rs7216064 1.000 rs58122682 chr17:65876915 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.19 -0.45 3.8e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6430585 0.528 rs10496738 chr2:136751488 C/T cg07169764 chr2:136633963 MCM6 1.28 20.79 0.75 1.25e-62 Corneal structure; LIHC cis rs9303401 1.000 rs1390006 chr17:56890663 C/T cg10487724 chr17:56770010 TEX14;RAD51C -0.42 -6.34 -0.32 7.28e-10 Cognitive test performance; LIHC cis rs2559856 1.000 rs10745921 chr12:102087193 A/G cg12924262 chr12:102091054 CHPT1 0.53 8.5 0.42 6.13e-16 Blood protein levels; LIHC cis rs6748734 1.000 rs6724662 chr2:241831560 A/G cg20140201 chr2:241835670 C2orf54 -0.45 -6.15 -0.32 2.18e-9 Urinary metabolites; LIHC cis rs7618501 0.633 rs3774733 chr3:50037123 C/G cg24110177 chr3:50126178 RBM5 -0.48 -7.68 -0.38 1.68e-13 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.902 rs11042152 chr11:9020987 C/T cg12365402 chr11:9010492 NRIP3 0.34 8.63 0.42 2.3e-16 Hemoglobin concentration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23260799 chr11:451101 PTDSS2 0.38 6.24 0.32 1.3e-9 Cognitive function; LIHC cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs2742417 0.603 rs2742457 chr3:45767487 G/A cg04837898 chr3:45731254 SACM1L -0.51 -8.46 -0.42 8e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs67981189 0.634 rs221900 chr14:71604354 C/T cg15816911 chr14:71606274 NA 0.43 6.89 0.35 2.7e-11 Schizophrenia; LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg02782426 chr3:40428986 ENTPD3 -0.32 -5.89 -0.3 9.18e-9 Renal cell carcinoma; LIHC cis rs1953600 0.668 rs3122586 chr10:81950326 C/T cg27417294 chr10:81904244 PLAC9 -0.36 -6.16 -0.32 2.04e-9 Sarcoidosis; LIHC cis rs116248771 0.739 rs7648050 chr3:158377470 G/A cg16708174 chr3:158430962 RARRES1 0.48 6.38 0.33 5.61e-10 diarrhoeal disease at age 2; LIHC cis rs11711311 1.000 rs3773682 chr3:113520576 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.11 -0.36 6.63e-12 IgG glycosylation; LIHC cis rs7520050 0.771 rs4660882 chr1:46116292 C/T cg24296786 chr1:45957014 TESK2 -0.39 -5.88 -0.3 9.53e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg11764359 chr7:65958608 NA 0.59 6.14 0.32 2.32e-9 Diabetic kidney disease; LIHC cis rs2404602 0.647 rs10152247 chr15:76942252 T/G cg23625390 chr15:77176239 SCAPER -0.55 -9.13 -0.44 6.31e-18 Blood metabolite levels; LIHC cis rs2526882 0.541 rs2526859 chr14:71412207 C/T cg15816911 chr14:71606274 NA -0.43 -6.74 -0.34 6.73e-11 Schizophrenia; LIHC cis rs10752881 1.000 rs10797811 chr1:182984432 G/A ch.1.3577855R chr1:183094577 LAMC1 0.58 10.15 0.48 2.49e-21 Colorectal cancer; LIHC cis rs2549003 0.966 rs839 chr5:131819126 C/T cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.25e-20 Asthma (sex interaction); LIHC cis rs4805272 0.626 rs12610050 chr19:29331324 A/T cg14983838 chr19:29218262 NA 0.39 5.91 0.3 8.16e-9 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs9790314 0.934 rs455386 chr3:161102495 A/T cg04691961 chr3:161091175 C3orf57 -0.43 -6.61 -0.34 1.46e-10 Morning vs. evening chronotype; LIHC cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.04 0.31 3.93e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7095607 0.654 rs7081017 chr10:69954451 A/G cg18986048 chr10:69913749 MYPN 0.39 5.81 0.3 1.46e-8 Lung function (FVC); LIHC cis rs74233809 1.000 rs77860422 chr10:104748009 G/A cg03493300 chr10:104813866 CNNM2 0.44 5.76 0.3 1.85e-8 Birth weight; LIHC cis rs1790761 0.667 rs658768 chr11:67337808 G/A cg01069141 chr11:67398826 TBX10;NUDT8 0.38 6.69 0.34 8.86e-11 Mean corpuscular volume; LIHC cis rs7264396 0.832 rs224416 chr20:34138406 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.37 -6.42 -0.33 4.43e-10 Total cholesterol levels; LIHC cis rs6570726 0.791 rs7765687 chr6:145915100 A/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.71 -0.3 2.42e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs968567 0.539 rs174555 chr11:61579760 T/C cg07689907 chr11:61582574 FADS1 0.41 5.94 0.31 6.98e-9 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs2832191 0.671 rs68101501 chr21:30513229 G/T cg08807101 chr21:30365312 RNF160 -0.43 -6.11 -0.31 2.69e-9 Dental caries; LIHC cis rs2645694 0.626 rs2703143 chr4:77830441 A/G cg06046430 chr4:77819534 ANKRD56 0.5 6.18 0.32 1.82e-9 Emphysema distribution in smoking; LIHC cis rs72720396 0.789 rs12022460 chr1:91202257 A/G cg13456504 chr1:91191583 NA -0.53 -7.81 -0.39 7.23e-14 Morning vs. evening chronotype;Chronotype; LIHC trans rs9929218 1.000 rs12930371 chr16:68802936 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.57 8.85 0.43 4.66e-17 Colorectal cancer; LIHC cis rs1789 0.868 rs4631041 chr4:15673395 A/T cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.86 -0.3 1.07e-8 Blood protein levels; LIHC cis rs68170813 0.559 rs3801958 chr7:106961139 C/T cg02696742 chr7:106810147 HBP1 -0.52 -5.99 -0.31 5.3300000000000004e-09 Coronary artery disease; LIHC cis rs1401999 0.650 rs3749445 chr3:183638506 C/T cg05044414 chr3:183734942 ABCC5 0.32 5.87 0.3 1.05e-8 Anterior chamber depth; LIHC cis rs600626 0.578 rs10793126 chr11:75453982 C/T cg24262691 chr11:75473276 NA -0.4 -5.94 -0.31 6.96e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs9911578 1.000 rs2079703 chr17:56603978 G/A cg05425664 chr17:57184151 TRIM37 0.59 8.75 0.43 1e-16 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg05590025 chr7:65112418 INTS4L2 -0.58 -6.51 -0.33 2.61e-10 Diabetic kidney disease; LIHC cis rs17685 0.753 rs55812043 chr7:75747241 T/C cg04592579 chr7:75616294 TMEM120A 0.39 6.73 0.34 7.31e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12477438 0.765 rs10181422 chr2:99558970 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.1 -0.4 9.71e-15 Chronic sinus infection; LIHC cis rs2282032 0.527 rs3742666 chr14:90767860 T/C cg04374321 chr14:90722782 PSMC1 0.48 6.92 0.35 2.3e-11 Longevity; LIHC trans rs4332037 0.539 rs57148375 chr7:2025001 G/C cg11693508 chr17:37793320 STARD3 0.68 6.93 0.35 2.16e-11 Bipolar disorder; LIHC cis rs7584330 0.554 rs7598035 chr2:238434942 C/T cg08992911 chr2:238395768 MLPH 0.49 5.95 0.31 6.48e-9 Prostate cancer; LIHC cis rs12464483 0.524 rs1901906 chr2:30884576 A/G cg17749961 chr2:30669863 LCLAT1 -0.46 -6.01 -0.31 4.76e-9 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs1568889 1.000 rs7937778 chr11:28104605 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.81 0.35 4.36e-11 Bipolar disorder; LIHC cis rs6089584 0.627 rs35560719 chr20:60561917 A/C cg06108461 chr20:60628389 TAF4 -0.54 -7.35 -0.37 1.51e-12 Body mass index; LIHC cis rs2933343 0.716 rs9872706 chr3:128567105 A/G cg25356066 chr3:128598488 ACAD9 -0.53 -6.87 -0.35 3.08e-11 IgG glycosylation; LIHC cis rs644799 0.542 rs10831418 chr11:95468828 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.79 12.14 0.55 1.94e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10861342 1.000 rs11112371 chr12:105499021 T/C cg23923672 chr12:105501055 KIAA1033 0.66 7.7 0.38 1.49e-13 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12457740 chr3:56590942 CCDC66 -0.47 -6.74 -0.34 6.6e-11 Pancreatic cancer; LIHC cis rs4665809 0.941 rs6735145 chr2:26270302 T/C cg04944784 chr2:26401820 FAM59B -0.64 -8.06 -0.4 1.3e-14 Gut microbiome composition (summer); LIHC cis rs826838 0.834 rs826874 chr12:39122599 C/A cg26384229 chr12:38710491 ALG10B -0.49 -7.58 -0.38 3.17e-13 Heart rate; LIHC cis rs1371867 0.846 rs1788194 chr8:101277916 T/C cg06002616 chr8:101225028 SPAG1 -0.35 -5.85 -0.3 1.17e-8 Atrioventricular conduction; LIHC trans rs6461049 0.800 rs3778977 chr7:2159746 C/T cg04565464 chr8:145669602 NFKBIL2 0.38 6.37 0.33 6.15e-10 Schizophrenia; LIHC cis rs9583531 0.689 rs9515273 chr13:111383427 G/C cg24331049 chr13:111365604 ING1 0.79 12.72 0.57 1.25e-30 Coronary artery disease; LIHC cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg25894440 chr7:65020034 NA 0.51 5.9 0.3 8.83e-9 Diabetic kidney disease; LIHC cis rs67478160 0.595 rs1475007 chr14:104297147 A/G cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.31 -0.37 1.89e-12 Schizophrenia; LIHC cis rs941873 0.869 rs7917610 chr10:81117237 T/C cg09469691 chr10:81107165 PPIF 0.69 10.52 0.49 1.27e-22 Height; LIHC cis rs13191362 1.000 rs36007635 chr6:163009335 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12611088 0.541 rs2599445 chr19:44005025 C/G cg13740135 chr19:44006432 PHLDB3 -0.42 -6.18 -0.32 1.83e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC trans rs8073060 0.586 rs72829923 chr17:34045089 T/A cg19694781 chr19:47549865 TMEM160 1.22 12.75 0.57 9.9e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg20887711 chr4:1340912 KIAA1530 -0.48 -7.36 -0.37 1.41e-12 Obesity-related traits; LIHC cis rs40363 0.645 rs6501177 chr16:3523681 C/T cg22508957 chr16:3507546 NAT15 0.49 8.85 0.43 4.96e-17 Tuberculosis; LIHC cis rs775227 0.574 rs79709668 chr3:113161265 G/A cg18753928 chr3:113234510 CCDC52 -0.43 -5.75 -0.3 1.95e-8 Dental caries; LIHC cis rs13256369 0.950 rs13248096 chr8:8577476 C/T cg17143192 chr8:8559678 CLDN23 0.63 10.16 0.48 2.24e-21 Obesity-related traits; LIHC cis rs4517514 0.509 rs12417652 chr11:89905239 T/G cg05041596 chr11:89867385 NAALAD2 0.42 6.77 0.34 5.49e-11 Trans fatty acid levels; LIHC cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg06618935 chr21:46677482 NA -0.33 -6.28 -0.32 1.03e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7618501 0.521 rs7615206 chr3:49937505 T/C cg24110177 chr3:50126178 RBM5 -0.55 -8.66 -0.42 1.95e-16 Intelligence (multi-trait analysis); LIHC cis rs1034435 0.692 rs6008739 chr22:48892542 T/C cg05992904 chr22:48892994 FAM19A5 -0.52 -10.94 -0.51 4.43e-24 Late-onset Alzheimer's disease; LIHC cis rs858239 0.539 rs28716381 chr7:23189015 G/A cg23682824 chr7:23144976 KLHL7 0.46 6.96 0.35 1.71e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs12701220 0.655 rs10215292 chr7:1135263 A/G cg00990874 chr7:1149470 C7orf50 -0.69 -9.85 -0.47 2.54e-20 Bronchopulmonary dysplasia; LIHC cis rs2153535 0.601 rs9502719 chr6:8541032 A/G cg07606381 chr6:8435919 SLC35B3 0.78 11.28 0.52 2.74e-25 Motion sickness; LIHC cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg11062466 chr8:58055876 NA 0.53 7.68 0.38 1.7e-13 Developmental language disorder (linguistic errors); LIHC cis rs72781680 0.898 rs6545127 chr2:24060670 C/T cg08917208 chr2:24149416 ATAD2B 0.84 8.03 0.4 1.54e-14 Lymphocyte counts; LIHC cis rs11122272 0.735 rs2437148 chr1:231513979 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC trans rs10761482 0.566 rs4505011 chr10:62200308 T/C cg17314160 chr12:110399253 GIT2 -0.41 -6.23 -0.32 1.36e-9 Schizophrenia; LIHC cis rs17401966 1.000 rs7520935 chr1:10354271 G/T cg15208524 chr1:10270712 KIF1B 0.45 6.56 0.33 2.04e-10 Hepatocellular carcinoma; LIHC cis rs7918232 0.830 rs7915902 chr10:27410734 T/C cg14442939 chr10:27389572 ANKRD26 0.72 7.07 0.36 8.86e-12 Breast cancer; LIHC cis rs1801251 1.000 rs2592113 chr2:233669553 C/T cg08000102 chr2:233561755 GIGYF2 0.75 11.22 0.52 4.19e-25 Coronary artery disease; LIHC cis rs3741404 0.791 rs2282491 chr11:63918373 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.95 16.11 0.66 7.33e-44 Platelet count; LIHC cis rs4727027 0.782 rs10245343 chr7:148796333 T/C cg23583168 chr7:148888333 NA -0.67 -8.41 -0.41 1.14e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs36051895 0.632 rs57698263 chr9:5143262 G/A cg02405213 chr9:5042618 JAK2 -0.67 -11.68 -0.53 9.22e-27 Pediatric autoimmune diseases; LIHC cis rs4407350 1.000 rs4407350 chr22:44922275 G/A cg26276947 chr22:44892394 LDOC1L 0.35 6.41 0.33 4.8e-10 Intelligence (multi-trait analysis); LIHC cis rs11676348 0.776 rs11690316 chr2:219017462 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.54 -7.3 -0.37 1.99e-12 Ulcerative colitis; LIHC cis rs473651 0.716 rs548179 chr2:239320505 G/A cg21699342 chr2:239360505 ASB1 0.33 6.52 0.33 2.6e-10 Multiple system atrophy; LIHC cis rs9640161 0.750 rs73170185 chr7:150030191 C/A cg17279839 chr7:150038598 RARRES2 0.58 11.8 0.54 3.52e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs4474465 1.000 rs2063726 chr11:78183533 T/C cg02023728 chr11:77925099 USP35 0.34 6.15 0.32 2.1e-9 Alzheimer's disease (survival time); LIHC cis rs4689592 0.523 rs6446565 chr4:7074027 A/G cg06697600 chr4:7070879 GRPEL1 -0.66 -10.65 -0.5 4.62e-23 Monocyte percentage of white cells; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg18538332 chr22:24372958 LOC391322 -0.66 -10.02 -0.48 6.77e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9916302 0.861 rs8079590 chr17:37426201 T/C cg00129232 chr17:37814104 STARD3 -0.39 -6.33 -0.32 7.5e-10 Glomerular filtration rate (creatinine); LIHC cis rs8064299 0.655 rs895691 chr17:72766300 G/T cg25054828 chr17:72772726 NAT9;TMEM104 0.64 10.16 0.48 2.35e-21 Monocyte count; LIHC cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg21280719 chr6:42927975 GNMT -0.32 -7.21 -0.36 3.72e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1865760 1.000 rs6910138 chr6:25904352 C/G cg17691542 chr6:26056736 HIST1H1C 0.39 5.91 0.3 8.47e-9 Height; LIHC cis rs9611565 0.559 rs7290991 chr22:41964361 C/G cg03806693 chr22:41940476 POLR3H -0.87 -9.75 -0.47 5.67e-20 Vitiligo; LIHC trans rs10448080 0.879 rs240946 chr8:28568905 A/G cg16901082 chr8:26435609 DPYSL2 -0.38 -6.66 -0.34 1.11e-10 Height; LIHC cis rs9534288 0.797 rs718530 chr13:46563653 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.41e-15 Blood protein levels; LIHC trans rs7613875 0.600 rs2247510 chr3:50126215 A/C cg21665057 chr3:196295764 WDR53;FBXO45 0.41 6.17 0.32 1.93e-9 Body mass index; LIHC cis rs8062405 1.000 rs55830740 chr16:28847149 G/C cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3096299 0.933 rs28608022 chr16:89454292 C/T cg02187348 chr16:89574699 SPG7 0.5 7.54 0.38 4.31e-13 Multiple myeloma (IgH translocation); LIHC cis rs9858542 0.537 rs73086105 chr3:49356577 A/G cg07636037 chr3:49044803 WDR6 -0.63 -6.44 -0.33 4.11e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2806561 0.929 rs6669568 chr1:23540469 G/A cg19743168 chr1:23544995 NA -0.41 -7.59 -0.38 3.15e-13 Height; LIHC cis rs6546550 0.835 rs3752781 chr2:70124316 T/A cg02498382 chr2:70120550 SNRNP27 -0.45 -7.54 -0.38 4.36e-13 Prevalent atrial fibrillation; LIHC cis rs921968 0.509 rs72963905 chr2:219547027 T/G cg02985541 chr2:219472218 PLCD4 -0.39 -5.94 -0.31 7.04e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs4478037 0.822 rs77355992 chr3:33107518 T/C cg16652328 chr3:33138982 GLB1;TMPPE -0.57 -6.78 -0.34 5.27e-11 Major depressive disorder; LIHC cis rs897984 0.806 rs10782002 chr16:30946506 A/G cg02466173 chr16:30829666 NA 0.42 6.99 0.35 1.49e-11 Dementia with Lewy bodies; LIHC cis rs35306767 0.903 rs10508208 chr10:910983 C/T cg20503657 chr10:835505 NA 1.0 11.7 0.53 7.85e-27 Eosinophil percentage of granulocytes; LIHC cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg08132940 chr7:1081526 C7orf50 -0.79 -6.72 -0.34 7.83e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs13113518 0.812 rs12505880 chr4:56307155 C/A cg15358633 chr12:38710606 ALG10B 0.43 6.11 0.31 2.78e-9 Height; LIHC cis rs763121 0.889 rs1043402 chr22:38879688 G/A cg14440974 chr22:39074834 NA -0.38 -5.91 -0.3 8.24e-9 Menopause (age at onset); LIHC cis rs796364 1.000 rs281762 chr2:200799201 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.16 0.44 4.71e-18 Schizophrenia; LIHC cis rs9430161 0.611 rs35033941 chr1:11034382 C/T cg27631724 chr1:11040367 C1orf127 0.37 6.9 0.35 2.55e-11 Ewing sarcoma; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg10150615 chr22:24372951 LOC391322 -0.57 -8.44 -0.42 9.14e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.52 0.46 3.35e-19 Bipolar disorder; LIHC cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg12516959 chr21:47718080 NA 0.43 6.73 0.34 7.26e-11 Testicular germ cell tumor; LIHC cis rs9914988 0.943 rs4795467 chr17:27180784 C/T cg20469991 chr17:27169893 C17orf63 -0.62 -6.93 -0.35 2.05e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs10197940 0.662 rs10173699 chr2:152281561 C/G cg06191203 chr2:152266755 RIF1 0.47 7.82 0.39 6.71e-14 Lung cancer; LIHC cis rs763121 0.853 rs3788544 chr22:39064966 C/T cg06022373 chr22:39101656 GTPBP1 0.66 11.41 0.52 9.23e-26 Menopause (age at onset); LIHC cis rs6912958 0.559 rs242267 chr6:88061837 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.43 -8.29 -0.41 2.57e-15 Monocyte percentage of white cells; LIHC cis rs3096299 0.679 rs3102338 chr16:89442250 C/G cg08822215 chr16:89438651 ANKRD11 -0.51 -8.06 -0.4 1.33e-14 Multiple myeloma (IgH translocation); LIHC cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg20887711 chr4:1340912 KIAA1530 0.47 6.26 0.32 1.17e-9 Obesity-related traits; LIHC cis rs992157 0.710 rs13026485 chr2:219057984 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.79 -13.08 -0.58 5.72e-32 Colorectal cancer; LIHC cis rs79976124 0.879 rs12213669 chr6:66627704 G/A cg07460842 chr6:66804631 NA 0.64 6.77 0.34 5.66e-11 Type 2 diabetes; LIHC cis rs28830936 0.966 rs11635415 chr15:42133502 T/C cg17847044 chr15:42102381 MAPKBP1 -0.3 -6.14 -0.31 2.32e-9 Diastolic blood pressure; LIHC cis rs12893668 0.673 rs2296482 chr14:104029819 T/G cg24130564 chr14:104152367 KLC1 -0.55 -8.91 -0.43 3.16e-17 Reticulocyte count; LIHC cis rs903552 0.932 rs2172851 chr15:102012626 C/T cg19295451 chr15:102010161 PCSK6 -0.53 -7.21 -0.36 3.59e-12 Diabetic kidney disease; LIHC cis rs881375 0.678 rs10760129 chr9:123700183 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.44 0.33 4.16e-10 Rheumatoid arthritis; LIHC cis rs2334880 0.641 rs12325234 chr16:71459628 A/T cg06353428 chr16:71660113 MARVELD3 -1.06 -9.7 -0.46 8.27e-20 Malaria; LIHC cis rs9733 0.519 rs2184833 chr1:150675483 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.72 -0.3 2.28e-8 Tonsillectomy; LIHC cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg05552183 chr6:42928497 GNMT 0.68 10.11 0.48 3.35e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs74181299 0.684 rs12713532 chr2:65356552 G/C cg05010058 chr2:65284262 CEP68 -0.42 -6.93 -0.35 2.04e-11 Pulse pressure; LIHC cis rs6840360 0.533 rs4696295 chr4:152717430 T/C cg22705602 chr4:152727874 NA 0.4 8.36 0.41 1.57e-15 Intelligence (multi-trait analysis); LIHC cis rs8056893 0.842 rs3785114 chr16:68372323 C/G cg02226672 chr16:68398533 SMPD3 0.41 5.78 0.3 1.69e-8 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC trans rs12478296 1.000 rs12478296 chr2:243048760 A/G cg01596870 chr19:55963115 NA 0.64 8.74 0.43 1.1e-16 Obesity-related traits; LIHC cis rs616147 0.627 rs9871799 chr3:39484320 G/A cg17944282 chr3:39448217 RPSA 0.42 5.88 0.3 9.61e-9 Amyotrophic lateral sclerosis;Amyotrophic lateral sclerosis (sporadic); LIHC trans rs6598955 0.671 rs17163868 chr1:26648381 A/G cg07461501 chr17:79650226 HGS;ARL16 0.76 8.62 0.42 2.49e-16 Obesity-related traits; LIHC cis rs11671005 0.735 rs3826681 chr19:58918764 A/G cg25952890 chr19:58913133 NA 0.69 7.4 0.37 1.07e-12 Mean platelet volume; LIHC cis rs6977660 0.943 rs10225293 chr7:19840636 C/T cg07541023 chr7:19748670 TWISTNB -0.37 -5.91 -0.3 8.48e-9 Thyroid stimulating hormone; LIHC cis rs7945718 0.839 rs2033908 chr11:12838286 G/T cg25843174 chr11:12811716 TEAD1 0.32 7.52 0.38 4.78e-13 Educational attainment (years of education); LIHC cis rs72634258 0.554 rs1012477 chr1:7858135 C/G cg26816564 chr1:7831052 VAMP3 -0.59 -6.14 -0.32 2.31e-9 Inflammatory bowel disease; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 21.68 0.76 3.28e-66 Prudent dietary pattern; LIHC cis rs3862260 0.509 rs12076924 chr1:120165826 C/T cg16322792 chr1:120165303 ZNF697 0.52 9.25 0.45 2.53e-18 Systemic lupus erythematosus; LIHC cis rs72634258 0.945 rs6577459 chr1:8100173 G/T cg00042356 chr1:8021962 PARK7 0.85 8.33 0.41 1.95e-15 Inflammatory bowel disease; LIHC cis rs12477438 0.520 rs13023744 chr2:99738224 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs926392 0.965 rs714108 chr20:37687838 G/A cg16355469 chr20:37678765 NA 0.37 5.9 0.3 8.89e-9 Dialysis-related mortality; LIHC cis rs2976388 0.578 rs3736010 chr8:143817503 T/C cg06565975 chr8:143823917 SLURP1 -0.45 -8.19 -0.4 5.37e-15 Urinary tract infection frequency; LIHC cis rs826838 0.967 rs4768330 chr12:39129399 T/C cg26384229 chr12:38710491 ALG10B -0.64 -9.23 -0.45 2.95e-18 Heart rate; LIHC cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg12463550 chr7:65579703 CRCP -0.66 -6.96 -0.35 1.78e-11 Diabetic kidney disease; LIHC trans rs2243480 1.000 rs67536397 chr7:65947917 G/A cg10756647 chr7:56101905 PSPH 1.0 11.41 0.53 8.84e-26 Diabetic kidney disease; LIHC cis rs1401999 0.966 rs1533682 chr3:183634879 A/G cg05044414 chr3:183734942 ABCC5 0.33 5.81 0.3 1.4e-8 Anterior chamber depth; LIHC cis rs5769765 0.773 rs9616382 chr22:50312979 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs5770917 1.000 rs115743514 chr22:51011933 T/C cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.5 -6.65 -0.34 1.19e-10 Narcolepsy; LIHC trans rs35110281 0.811 rs1122873 chr21:45044672 G/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.15 0.32 2.14e-9 Mean corpuscular volume; LIHC cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg16606324 chr3:10149918 C3orf24 0.53 5.88 0.3 9.53e-9 Alzheimer's disease; LIHC cis rs3748682 0.861 rs2291297 chr1:38272660 G/A cg12658694 chr1:38397304 INPP5B 0.44 6.03 0.31 4.2e-9 Hypothyroidism; LIHC cis rs9393777 0.588 rs6456727 chr6:26471155 T/C cg12826209 chr6:26865740 GUSBL1 0.66 7.92 0.39 3.43e-14 Intelligence (multi-trait analysis); LIHC cis rs1843834 0.505 rs3820763 chr2:225347270 A/G cg22455342 chr2:225449267 CUL3 -0.54 -7.79 -0.39 7.89e-14 IgE levels in asthmatics (D.p. specific); LIHC cis rs6867032 0.834 rs4526149 chr5:1990166 G/A cg26168224 chr5:2018326 NA -0.27 -6.43 -0.33 4.41e-10 Gut microbiome composition (winter); LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg24693881 chr1:107596107 NA -0.52 -9.02 -0.44 1.34e-17 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg27286337 chr10:134555280 INPP5A 0.95 13.47 0.59 1.73e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11711311 0.955 rs11715350 chr3:113418376 G/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.44 7.93 0.39 3.2e-14 IgG glycosylation; LIHC cis rs7615952 0.599 rs6438953 chr3:125724951 T/C cg05084668 chr3:125655381 ALG1L -0.43 -7.14 -0.36 5.47e-12 Blood pressure (smoking interaction); LIHC cis rs7762018 0.769 rs4716385 chr6:170127608 G/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.54 6.07 0.31 3.45e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9309473 1.000 rs10189574 chr2:73698518 C/A cg20560298 chr2:73613845 ALMS1 -0.52 -6.25 -0.32 1.26e-9 Metabolite levels; LIHC cis rs9443189 0.901 rs2038625 chr6:76560968 G/A cg01950844 chr6:76311363 SENP6 -0.52 -6.76 -0.34 5.8200000000000003e-11 Prostate cancer; LIHC cis rs727505 1.000 rs10241173 chr7:124453258 A/G cg23710748 chr7:124431027 NA -0.32 -5.72 -0.3 2.35e-8 Lewy body disease; LIHC cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg15691649 chr6:25882328 NA -0.51 -7.38 -0.37 1.22e-12 Blood metabolite levels; LIHC cis rs72843506 0.656 rs8073875 chr17:19939059 A/G cg12065943 chr17:19881925 AKAP10 -0.41 -6.93 -0.35 2.14e-11 Schizophrenia; LIHC cis rs9649465 0.967 rs2299986 chr7:123369539 T/C cg03229431 chr7:123269106 ASB15 -0.37 -8.01 -0.4 1.84e-14 Migraine; LIHC cis rs9393777 0.623 rs9358945 chr6:26472114 C/T cg12826209 chr6:26865740 GUSBL1 -0.62 -6.64 -0.34 1.21e-10 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.752 rs7578606 chr2:23902360 T/C cg08917208 chr2:24149416 ATAD2B 0.98 8.06 0.4 1.29e-14 Lymphocyte counts; LIHC cis rs3736485 0.868 rs9744054 chr15:51933163 C/T cg08986416 chr15:51914746 DMXL2 -0.43 -6.12 -0.31 2.5e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1814175 0.616 rs847641 chr11:49919261 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs5753618 0.539 rs1034588 chr22:31616301 A/G cg22777020 chr22:31556080 RNF185 -0.54 -6.14 -0.32 2.23e-9 Colorectal cancer; LIHC cis rs4631830 0.900 rs9787697 chr10:51533376 C/T cg20129853 chr10:51489980 NA -0.42 -9.1 -0.44 7.71e-18 Prostate-specific antigen levels; LIHC cis rs919433 1.000 rs7422899 chr2:198163527 G/C cg10820045 chr2:198174542 NA -0.58 -9.57 -0.46 2.2e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs7618501 0.902 rs7645061 chr3:49868842 C/T cg19936157 chr1:113287238 NA -0.33 -6.03 -0.31 4.15e-9 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg23758822 chr17:41437982 NA 0.94 17.9 0.7 5.08e-51 Menopause (age at onset); LIHC cis rs17685 0.672 rs55807301 chr7:75807401 C/A cg04610667 chr7:75704037 NA -0.33 -5.99 -0.31 5.2e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9916302 0.861 rs644173 chr17:37430519 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.47 -0.59 1.85e-33 Glomerular filtration rate (creatinine); LIHC cis rs8180040 0.593 rs10433549 chr3:47031433 C/T cg27129171 chr3:47204927 SETD2 -0.53 -8.72 -0.43 1.21e-16 Colorectal cancer; LIHC cis rs11229555 0.598 rs12289876 chr11:58185250 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6942756 0.806 rs10248810 chr7:128993806 G/A cg02491457 chr7:128862824 NA -0.57 -8.66 -0.42 1.83e-16 White matter hyperintensity burden; LIHC cis rs921968 0.541 rs2556391 chr2:219556346 T/C cg02985541 chr2:219472218 PLCD4 -0.39 -6.06 -0.31 3.65e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs1153858 1.000 rs4775911 chr15:45649787 G/T cg26924012 chr15:45694286 SPATA5L1 -0.91 -18.26 -0.7 1.76e-52 Homoarginine levels; LIHC cis rs2635047 0.935 rs1398218 chr18:44745721 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.43 5.81 0.3 1.44e-8 Educational attainment; LIHC cis rs600806 0.751 rs1933182 chr1:109999838 A/C cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.32 -0.32 8.08e-10 Intelligence (multi-trait analysis); LIHC cis rs9303280 0.934 rs56380902 chr17:38066372 T/C cg11212589 chr17:38028394 ZPBP2 0.33 6.75 0.34 6.24e-11 Self-reported allergy; LIHC cis rs1348850 0.526 rs4893829 chr2:178399810 A/G cg27490568 chr2:178487706 NA -0.91 -10.46 -0.49 2.07e-22 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg12419862 chr22:24373484 LOC391322 -0.78 -12.19 -0.55 1.27e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs921968 0.643 rs613539 chr2:219455967 G/T cg02985541 chr2:219472218 PLCD4 0.45 8.41 0.41 1.16e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs35110281 0.782 rs1584917 chr21:45042365 A/G cg21573476 chr21:45109991 RRP1B -0.54 -10.25 -0.48 1.15e-21 Mean corpuscular volume; LIHC cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.77 0.39 8.99e-14 Bipolar disorder; LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg15586393 chr4:1244086 CTBP1;C4orf42 -0.42 -5.91 -0.3 8.22e-9 Longevity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14490972 chr6:43484812 POLR1C;YIPF3 0.44 6.21 0.32 1.55e-9 Cognitive function; LIHC cis rs35306767 0.714 rs10508206 chr10:1075777 A/C cg20503657 chr10:835505 NA 0.57 6.25 0.32 1.24e-9 Eosinophil percentage of granulocytes; LIHC cis rs8017423 0.967 rs11628812 chr14:90713720 G/T cg04374321 chr14:90722782 PSMC1 -0.75 -14.66 -0.62 4.22e-38 Mortality in heart failure; LIHC cis rs1707322 1.000 rs10890378 chr1:46410657 A/G cg06784218 chr1:46089804 CCDC17 -0.35 -6.26 -0.32 1.13e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg22105103 chr4:187893119 NA 0.34 8.28 0.41 2.79e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7000551 0.751 rs2461482 chr8:22382898 C/T cg12081754 chr8:22256438 SLC39A14 0.41 6.3 0.32 9.21e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs9768139 0.683 rs28682392 chr7:158116004 A/G cg25566285 chr7:158114605 PTPRN2 0.23 6.25 0.32 1.23e-9 Calcium levels; LIHC cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg05665937 chr4:1216051 CTBP1 0.45 6.26 0.32 1.17e-9 Obesity-related traits; LIHC cis rs9921222 0.542 rs9926968 chr16:381561 A/C cg26913058 chr16:419975 MRPL28 -0.5 -6.85 -0.35 3.37e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs3808502 0.527 rs2736374 chr8:11113828 A/G cg14033944 chr8:11627058 NEIL2 0.59 6.98 0.35 1.57e-11 Neuroticism; LIHC cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg08392591 chr16:89556376 ANKRD11 0.57 9.17 0.44 4.62e-18 Multiple myeloma (IgH translocation); LIHC cis rs9560113 0.922 rs4773377 chr13:112174152 G/C cg14154082 chr13:112174009 NA 0.29 6.1 0.31 2.81e-9 Menarche (age at onset); LIHC cis rs739401 0.588 rs10219272 chr11:3020789 G/A cg05729581 chr11:3078854 CARS -0.42 -5.92 -0.3 7.86e-9 Longevity; LIHC cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.1 12.24 0.55 8.04e-29 Platelet count; LIHC cis rs13118159 0.725 rs71614967 chr4:1341291 A/G cg13395646 chr4:1353034 KIAA1530 -0.66 -9.03 -0.44 1.32e-17 Longevity; LIHC cis rs763121 0.785 rs5750646 chr22:39013830 T/C cg06022373 chr22:39101656 GTPBP1 0.75 15.03 0.63 1.44e-39 Menopause (age at onset); LIHC cis rs826838 0.935 rs7301104 chr12:39182821 C/T cg26384229 chr12:38710491 ALG10B 0.85 11.0 0.51 2.59e-24 Heart rate; LIHC cis rs6952808 0.965 rs11768541 chr7:1894884 G/A cg04267008 chr7:1944627 MAD1L1 -0.61 -9.18 -0.44 4.36e-18 Bipolar disorder and schizophrenia; LIHC cis rs4423214 1.000 rs12419279 chr11:71139061 T/A cg05163923 chr11:71159392 DHCR7 0.92 14.64 0.62 5.03e-38 Vitamin D levels; LIHC cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.86 0.8 1.15e-78 Prudent dietary pattern; LIHC cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg10802521 chr3:52805072 NEK4 -0.44 -7.24 -0.36 2.92e-12 Bipolar disorder; LIHC cis rs11031096 0.711 rs10767881 chr11:4205122 C/G cg18678763 chr11:4115507 RRM1 -0.44 -6.24 -0.32 1.29e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs12464483 0.524 rs4952173 chr2:30888346 G/T cg17749961 chr2:30669863 LCLAT1 0.47 6.01 0.31 4.8e-9 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs4927850 0.723 rs7630825 chr3:195753740 T/C cg01181863 chr3:195395398 SDHAP2 -0.59 -8.16 -0.4 6.65e-15 Pancreatic cancer; LIHC cis rs7659604 0.539 rs2063165 chr4:122750005 A/G cg20573242 chr4:122745356 CCNA2 0.52 7.64 0.38 2.22e-13 Type 2 diabetes; LIHC cis rs7927771 0.832 rs7924485 chr11:47419129 A/G cg20307385 chr11:47447363 PSMC3 0.47 6.06 0.31 3.56e-9 Subjective well-being; LIHC cis rs929354 0.742 rs6459734 chr7:156935454 A/G cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs10056811 0.538 rs4703645 chr5:74361140 A/G cg19683494 chr5:74908142 NA 0.69 7.65 0.38 2.07e-13 Coronary artery disease; LIHC cis rs17539620 0.624 rs871068 chr6:154837514 C/A cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09331995 chr7:27309021 NA 0.42 6.3 0.32 9.38e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2991971 0.810 rs2036021 chr1:45901370 G/A cg05343316 chr1:45956843 TESK2 -0.45 -6.6 -0.34 1.57e-10 High light scatter reticulocyte count; LIHC cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg03517284 chr6:25882590 NA -0.99 -12.87 -0.57 3.42e-31 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg11766577 chr21:47581405 C21orf56 0.45 7.71 0.38 1.34e-13 Testicular germ cell tumor; LIHC cis rs28374715 0.662 rs691906 chr15:41474636 T/A cg18705301 chr15:41695430 NDUFAF1 0.83 9.69 0.46 9.18e-20 Ulcerative colitis; LIHC cis rs74181299 0.964 rs2540948 chr2:65284623 T/C cg05010058 chr2:65284262 CEP68 0.41 6.86 0.35 3.18e-11 Pulse pressure; LIHC trans rs61931739 0.534 rs10844801 chr12:34230940 A/T cg26384229 chr12:38710491 ALG10B 0.58 7.61 0.38 2.74e-13 Morning vs. evening chronotype; LIHC cis rs425277 1.000 rs55826501 chr1:2059143 G/A cg24578937 chr1:2090814 PRKCZ 0.45 7.31 0.37 1.86e-12 Height; LIHC cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg00343986 chr7:65444356 GUSB 0.44 6.12 0.31 2.49e-9 Calcium levels; LIHC cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg02353165 chr6:42928485 GNMT 0.6 8.96 0.44 2.21e-17 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3767633 0.925 rs4656339 chr1:161915387 A/T cg09175582 chr1:161736000 ATF6 0.54 6.53 0.33 2.45e-10 IgG glycosylation; LIHC cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg14222432 chr12:29376421 FAR2 0.38 7.38 0.37 1.2e-12 QT interval; LIHC cis rs7666738 0.830 rs13134819 chr4:98919885 G/C cg05340658 chr4:99064831 C4orf37 0.65 12.08 0.55 3.19e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs2153535 0.580 rs9505446 chr6:8448691 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs4819052 0.765 rs2838852 chr21:46677037 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.33 0.52 1.75e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7208859 0.673 rs3764420 chr17:29164154 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.45 0.62 2.79e-37 Prudent dietary pattern; LIHC cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg00343986 chr7:65444356 GUSB -0.45 -6.28 -0.32 1.05e-9 Calcium levels; LIHC trans rs2739330 0.929 rs5751775 chr22:24266726 T/C cg06437703 chr8:37914619 EIF4EBP1 -0.52 -7.9 -0.39 3.76e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7937890 0.559 rs2597208 chr11:14472329 A/C cg02886208 chr11:14281011 SPON1 -0.46 -6.44 -0.33 4e-10 Mitochondrial DNA levels; LIHC cis rs332507 0.830 rs4678144 chr3:124404399 C/T cg05980111 chr3:124395277 KALRN -0.45 -6.95 -0.35 1.8e-11 Plateletcrit; LIHC cis rs1401999 0.546 rs4148593 chr3:183649870 A/G cg01324343 chr3:183735012 ABCC5 0.38 6.27 0.32 1.06e-9 Anterior chamber depth; LIHC cis rs3859192 0.561 rs12451547 chr17:38181168 T/C cg17467752 chr17:38218738 THRA -0.53 -9.28 -0.45 1.98e-18 White blood cell count; LIHC cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg02290350 chr8:58132656 NA 0.47 9.31 0.45 1.6e-18 Developmental language disorder (linguistic errors); LIHC cis rs4789452 0.774 rs55727612 chr17:75381723 C/T cg06761530 chr17:75373219 SEPT9 -0.47 -6.05 -0.31 3.88e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg06601766 chr17:61851465 DDX42;CCDC47 0.57 8.63 0.42 2.31e-16 Height; LIHC cis rs6701037 0.681 rs34370567 chr1:175131340 C/T cg17845761 chr1:175162550 KIAA0040 -0.4 -6.75 -0.34 6.48e-11 Alcohol dependence; LIHC cis rs826838 0.967 rs7970069 chr12:38810631 T/C cg13010199 chr12:38710504 ALG10B 0.65 7.82 0.39 6.73e-14 Heart rate; LIHC cis rs10416265 0.528 rs3826906 chr19:33620897 C/T cg17764715 chr19:33622953 WDR88 0.53 7.22 0.36 3.42e-12 Bone properties (heel); LIHC cis rs4272321 1 rs4272321 chr7:157951835 A/G cg02538280 chr7:157956927 PTPRN2 0.36 7.88 0.39 4.55e-14 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; LIHC cis rs55702914 0.837 rs2195507 chr2:198172336 T/C cg10820045 chr2:198174542 NA -0.41 -6.1 -0.31 2.85e-9 Major depression and alcohol dependence; LIHC cis rs2153535 0.601 rs9328487 chr6:8529378 G/C cg07606381 chr6:8435919 SLC35B3 0.79 11.72 0.54 6.76e-27 Motion sickness; LIHC cis rs4474465 0.688 rs4457782 chr11:78284733 A/G cg27205649 chr11:78285834 NARS2 0.5 7.79 0.39 8.35e-14 Alzheimer's disease (survival time); LIHC cis rs2559856 0.935 rs2559864 chr12:102084710 C/G cg12924262 chr12:102091054 CHPT1 0.51 8.25 0.41 3.56e-15 Blood protein levels; LIHC cis rs1448094 0.512 rs61930862 chr12:86246567 A/G cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg11494091 chr17:61959527 GH2 0.44 8.08 0.4 1.11e-14 Prudent dietary pattern; LIHC cis rs11098499 0.954 rs7436506 chr4:120393769 T/C cg09307838 chr4:120376055 NA 0.77 12.32 0.55 3.96e-29 Corneal astigmatism; LIHC cis rs922107 0.967 rs6699344 chr1:90023768 G/A cg15422784 chr1:90023713 LRRC8B -0.49 -8.01 -0.4 1.84e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs11958404 1.000 rs72816529 chr5:157411454 G/C cg05962755 chr5:157440814 NA 1.05 11.07 0.51 1.55e-24 IgG glycosylation; LIHC cis rs6748734 0.948 rs9973334 chr2:241838142 A/G cg20140201 chr2:241835670 C2orf54 -0.54 -8.36 -0.41 1.63e-15 Urinary metabolites; LIHC cis rs7917772 0.560 rs10786697 chr10:104378563 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.76 0.39 9.63e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs12220238 0.822 rs10824193 chr10:76261759 G/T cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.04 0.31 4.05e-9 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg14988396 chr8:25316392 CDCA2;KCTD9 0.52 6.69 0.34 9.09e-11 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs7582720 1.000 rs72934753 chr2:203750272 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs60871478 0.636 rs6976929 chr7:901382 C/T cg05535760 chr7:792225 HEATR2 -0.81 -6.59 -0.34 1.63e-10 Cerebrospinal P-tau181p levels; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.92 -0.3 7.75e-9 Total body bone mineral density; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs6546550 0.935 rs6747542 chr2:70106832 T/C cg02498382 chr2:70120550 SNRNP27 -0.38 -6.34 -0.32 7.44e-10 Prevalent atrial fibrillation; LIHC cis rs4820539 0.966 rs2267000 chr22:23455366 A/G cg21100191 chr22:23484243 RTDR1 0.84 15.3 0.64 1.32e-40 Bone mineral density; LIHC cis rs4589502 0.512 rs7183242 chr15:67096658 A/G cg12317470 chr15:67143691 NA 0.48 6.3 0.32 9.16e-10 Lung cancer (smoking interaction); LIHC cis rs7582720 1.000 rs72932588 chr2:203883193 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10540 0.908 rs71487293 chr11:486414 G/A cg03352830 chr11:487213 PTDSS2 0.68 5.86 0.3 1.08e-8 Body mass index; LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.861 rs11078913 chr17:37671714 G/T cg15445000 chr17:37608096 MED1 0.38 5.8 0.3 1.54e-8 Glomerular filtration rate (creatinine); LIHC cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg18230493 chr5:56204884 C5orf35 -0.46 -6.42 -0.33 4.45e-10 Initial pursuit acceleration; LIHC cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.13e-9 Menopause (age at onset); LIHC cis rs5758659 0.679 rs134870 chr22:42652317 T/C cg19513890 chr22:42538836 CYP2D7P1 -0.31 -5.95 -0.31 6.57e-9 Cognitive function; LIHC cis rs9367716 0.956 rs7757492 chr6:57120578 T/C cg03371099 chr6:57305889 PRIM2 0.35 5.74 0.3 2.14e-8 Coronary artery disease; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg18538332 chr22:24372958 LOC391322 -0.65 -9.7 -0.46 8.49e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs875971 0.545 rs67688847 chr7:65626051 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.5 0.38 5.5e-13 Aortic root size; LIHC cis rs6089584 0.606 rs6089599 chr20:60576992 A/G cg06108461 chr20:60628389 TAF4 0.52 7.15 0.36 5.17e-12 Body mass index; LIHC cis rs2243480 1.000 rs2533288 chr7:66056711 C/G cg12463550 chr7:65579703 CRCP 0.66 6.86 0.35 3.28e-11 Diabetic kidney disease; LIHC cis rs6442522 0.606 rs3274 chr3:15491756 G/A cg16303742 chr3:15540471 COLQ 0.39 6.37 0.33 6.05e-10 Uric acid levels; LIHC cis rs12477438 0.765 rs12470471 chr2:99689141 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.7 10.48 0.49 1.82e-22 Chronic sinus infection; LIHC cis rs1799949 0.930 rs1554063 chr17:41287145 T/C cg05368731 chr17:41323189 NBR1 0.67 11.1 0.51 1.22e-24 Menopause (age at onset); LIHC cis rs6912958 0.559 rs373646 chr6:88056896 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.59 11.11 0.51 1.1e-24 Monocyte percentage of white cells; LIHC cis rs748404 0.556 rs7166467 chr15:43440522 G/A cg27015174 chr15:43622946 ADAL;LCMT2 -0.36 -5.86 -0.3 1.06e-8 Lung cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24123311 chr19:48675164 NA 0.43 6.45 0.33 3.72e-10 Longevity; LIHC cis rs7523273 0.597 rs11118612 chr1:207979577 T/A cg22525895 chr1:207977042 MIR29B2 -0.59 -7.12 -0.36 6.45e-12 Schizophrenia; LIHC trans rs11098499 0.604 rs2389887 chr4:120570644 T/C cg25214090 chr10:38739885 LOC399744 0.54 8.51 0.42 5.4e-16 Corneal astigmatism; LIHC cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10503871 0.657 rs6997017 chr8:30341945 A/G cg26383811 chr8:30366931 RBPMS 0.43 7.46 0.37 7.13e-13 Metabolite levels (X-11787); LIHC cis rs96067 0.652 rs274132 chr1:36581978 C/T cg27506609 chr1:36549197 TEKT2 0.4 5.85 0.3 1.15e-8 Corneal structure; LIHC cis rs7914558 1.000 rs12780843 chr10:104769335 G/C cg04362960 chr10:104952993 NT5C2 0.38 5.75 0.3 1.97e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1816752 0.875 rs3783076 chr13:25064457 C/T cg02811702 chr13:24901961 NA 0.25 6.24 0.32 1.28e-9 Obesity-related traits; LIHC trans rs1814175 0.645 rs1851849 chr11:50012164 G/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs9733 0.544 rs72700902 chr1:150633347 C/T cg15448220 chr1:150897856 SETDB1 0.43 6.73 0.34 6.96e-11 Tonsillectomy; LIHC cis rs2932538 0.922 rs6681371 chr1:113101168 A/C cg22162597 chr1:113214053 CAPZA1 0.59 7.76 0.39 1.01e-13 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs2404602 0.692 rs3816266 chr15:76993835 T/G cg23625390 chr15:77176239 SCAPER 0.35 5.84 0.3 1.19e-8 Blood metabolite levels; LIHC cis rs807669 0.742 rs1206544 chr22:19215039 C/T cg02655711 chr22:19163373 SLC25A1 0.38 7.11 0.36 6.95e-12 Metabolite levels; LIHC cis rs2197308 0.765 rs68029712 chr12:37906585 T/G cg26384229 chr12:38710491 ALG10B 0.86 10.63 0.5 5.23e-23 Morning vs. evening chronotype; LIHC cis rs2072499 1.000 rs2241108 chr1:156181007 C/G cg24450063 chr1:156163899 SLC25A44 1.06 18.53 0.71 1.49e-53 Testicular germ cell tumor; LIHC cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg13866156 chr1:1669148 SLC35E2 -0.68 -12.75 -0.57 1.03e-30 Body mass index; LIHC cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg02353165 chr6:42928485 GNMT 0.77 11.88 0.54 1.75e-27 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs3783890 1.000 rs71429789 chr14:93745184 T/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.22 0.32 1.44e-9 Body mass index; LIHC cis rs11671005 0.652 rs56225452 chr19:59024646 C/T cg25952890 chr19:58913133 NA 0.64 6.29 0.32 9.49e-10 Mean platelet volume; LIHC cis rs644799 0.965 rs566877 chr11:95528045 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6442522 0.772 rs3890477 chr3:15489323 C/G cg16303742 chr3:15540471 COLQ 0.39 6.19 0.32 1.77e-9 Uric acid levels; LIHC cis rs7312774 0.618 rs2888892 chr12:107328071 C/T cg16260113 chr12:107380972 MTERFD3 0.91 11.75 0.54 5.13e-27 Severe influenza A (H1N1) infection; LIHC cis rs12611088 0.600 rs2682578 chr19:44012880 A/G cg13740135 chr19:44006432 PHLDB3 -0.41 -6.18 -0.32 1.84e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs7107174 0.892 rs2512534 chr11:77970039 T/A cg02023728 chr11:77925099 USP35 0.5 9.51 0.46 3.41e-19 Testicular germ cell tumor; LIHC cis rs7772486 0.720 rs4896837 chr6:146014168 C/T cg23711669 chr6:146136114 FBXO30 -0.73 -13.17 -0.58 2.47e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.659 rs12935851 chr17:56600244 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.89 11.61 0.53 1.73e-26 Cognitive test performance; LIHC trans rs1814175 0.591 rs11040589 chr11:49862449 A/G cg03929089 chr4:120376271 NA -0.83 -15.93 -0.65 4.11e-43 Height; LIHC cis rs7107174 0.901 rs10899493 chr11:78117534 T/C cg27205649 chr11:78285834 NARS2 -0.37 -5.82 -0.3 1.38e-8 Testicular germ cell tumor; LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.44 7.27 0.37 2.49e-12 Height; LIHC cis rs11628318 0.538 rs1190339 chr14:103103876 C/T cg23461800 chr14:103021989 NA -0.39 -5.89 -0.3 9.48e-9 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27499259 chr13:28400924 NA 0.41 6.22 0.32 1.49e-9 Cognitive function; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg09033563 chr22:24373618 LOC391322 -0.5 -6.96 -0.35 1.77e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs35110281 0.782 rs1454650 chr21:45012353 C/T cg21573476 chr21:45109991 RRP1B -0.56 -10.53 -0.49 1.17e-22 Mean corpuscular volume; LIHC trans rs11679072 1.000 rs7592764 chr2:240448167 A/C cg22966899 chr4:156268508 MAP9 0.6 6.19 0.32 1.7e-9 Blood pressure (smoking interaction); LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg00656387 chr3:40428638 ENTPD3 -0.5 -8.67 -0.42 1.83e-16 Renal cell carcinoma; LIHC cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg10360323 chr17:41437877 NA 0.41 6.09 0.31 3.1e-9 Menopause (age at onset); LIHC cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg08888203 chr3:10149979 C3orf24 0.6 6.79 0.34 4.83e-11 Alzheimer's disease; LIHC cis rs763121 0.853 rs3747170 chr22:39067331 G/A cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs12701220 0.842 rs10236293 chr7:1032637 G/A cg00990874 chr7:1149470 C7orf50 -0.7 -9.35 -0.45 1.13e-18 Bronchopulmonary dysplasia; LIHC cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg03264133 chr6:25882463 NA 0.93 12.68 0.57 1.9e-30 Blood metabolite levels; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg27309142 chr7:32801485 NA 0.39 6.07 0.31 3.34e-9 Lung function (FEV1); LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg02993280 chr1:107599747 PRMT6 0.69 11.36 0.52 1.36e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs34172651 0.583 rs200541 chr16:24733141 A/G cg04756594 chr16:24857601 SLC5A11 -0.55 -7.98 -0.4 2.18e-14 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.559 rs242279 chr6:88048191 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.32 0.37 1.74e-12 Monocyte percentage of white cells; LIHC cis rs9486715 0.867 rs2499775 chr6:97007340 C/T cg18709589 chr6:96969512 KIAA0776 -0.33 -5.84 -0.3 1.19e-8 Headache; LIHC cis rs9309473 0.632 rs7599076 chr2:73585519 G/T cg20560298 chr2:73613845 ALMS1 -0.46 -7.28 -0.37 2.26e-12 Metabolite levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22068764 chr1:170501645 GORAB 0.49 7.08 0.36 8.37e-12 Cognitive function; LIHC trans rs561341 1.000 rs497479 chr17:30328605 C/T cg20587970 chr11:113659929 NA -1.36 -12.15 -0.55 1.72e-28 Hip circumference adjusted for BMI; LIHC cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.49 0.33 3.07e-10 Mean platelet volume; LIHC cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs4713118 0.824 rs9366702 chr6:27734470 T/C cg20933634 chr6:27740509 NA 0.45 5.93 0.31 7.39e-9 Parkinson's disease; LIHC cis rs12368653 0.534 rs923828 chr12:58015494 G/A cg12615879 chr12:58013172 SLC26A10 0.35 6.62 0.34 1.38e-10 Multiple sclerosis; LIHC cis rs2412488 0.893 rs11723755 chr4:54310281 T/G cg22241045 chr4:54363911 LNX1 -0.42 -6.79 -0.34 5e-11 DNA methylation (variation); LIHC cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg16049864 chr8:95962084 TP53INP1 -0.67 -13.33 -0.58 6.41e-33 Type 2 diabetes; LIHC cis rs2274273 0.805 rs10131926 chr14:55713246 T/C cg04306507 chr14:55594613 LGALS3 0.35 6.57 0.33 1.89e-10 Protein biomarker; LIHC cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6545883 0.929 rs12617911 chr2:61740825 A/G cg15711740 chr2:61764176 XPO1 -0.42 -6.02 -0.31 4.61e-9 Tuberculosis; LIHC cis rs6840360 0.593 rs10016160 chr4:152693998 A/G cg22705602 chr4:152727874 NA -0.4 -8.52 -0.42 5.04e-16 Intelligence (multi-trait analysis); LIHC cis rs12594515 0.935 rs8042519 chr15:45996341 G/C cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs2984613 1 rs2984613 chr1:156197380 C/T cg24450063 chr1:156163899 SLC25A44 0.73 12.11 0.55 2.47e-28 Intracerebral hemorrhage;White matter hyperintensity burden; LIHC cis rs13108904 0.645 rs56115381 chr4:1324994 G/C cg13395646 chr4:1353034 KIAA1530 -0.86 -12.83 -0.57 4.99e-31 Obesity-related traits; LIHC cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7944735 0.508 rs4147730 chr11:47605427 C/T cg20307385 chr11:47447363 PSMC3 -0.54 -6.16 -0.32 2.01e-9 Intraocular pressure; LIHC trans rs1814175 0.935 rs7950947 chr11:49668369 C/T cg03929089 chr4:120376271 NA -0.89 -17.55 -0.69 1.28e-49 Height; LIHC cis rs9902453 0.935 rs9898424 chr17:28392946 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.85 -0.54 2.3e-27 Coffee consumption (cups per day); LIHC cis rs10276381 0.892 rs7786444 chr7:28154384 C/T cg23620719 chr7:28220237 JAZF1 0.61 7.64 0.38 2.26e-13 Crohn's disease; LIHC cis rs11112613 0.818 rs117644588 chr12:106022040 G/C cg03607813 chr12:105948248 NA 0.51 7.78 0.39 8.73e-14 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs877282 0.945 rs11253390 chr10:788678 A/G cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs7412746 0.566 rs2864871 chr1:150766964 T/C cg18016565 chr1:150552671 MCL1 0.53 9.94 0.47 1.27e-20 Melanoma; LIHC cis rs7520050 0.966 rs6429582 chr1:46321843 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 -0.4 -5.86 -0.3 1.09e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7552404 0.727 rs7547508 chr1:76327958 A/G cg10523679 chr1:76189770 ACADM -0.55 -6.95 -0.35 1.82e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.94 0.8 5.69e-79 Prudent dietary pattern; LIHC cis rs55823223 0.564 rs9894009 chr17:73850414 C/T cg14829360 chr17:73884958 NA -0.52 -7.83 -0.39 5.99e-14 Psoriasis; LIHC cis rs8180040 0.966 rs6790763 chr3:47572585 C/A cg27129171 chr3:47204927 SETD2 0.54 8.66 0.42 1.96e-16 Colorectal cancer; LIHC cis rs2066819 1.000 rs76151170 chr12:56659320 C/T cg26734620 chr12:56694298 CS 1.27 10.9 0.51 6.03e-24 Psoriasis vulgaris; LIHC cis rs11098499 0.754 rs11732087 chr4:120239831 A/G cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs2070488 0.775 rs7374458 chr3:38531211 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.61 0.56 3.24e-30 Electrocardiographic conduction measures; LIHC cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg06238570 chr21:40685208 BRWD1 0.58 6.91 0.35 2.38e-11 Cognitive function; LIHC cis rs7296418 0.630 rs7974099 chr12:123771475 A/G cg00376283 chr12:123451042 ABCB9 0.6 9.75 0.47 5.69e-20 Platelet count; LIHC cis rs77633900 0.614 rs2439984 chr15:76923917 T/C cg21673338 chr15:77095150 SCAPER -0.49 -7.27 -0.37 2.42e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs1800469 1.000 rs2241714 chr19:41869392 C/T cg09537434 chr19:41945824 ATP5SL 0.71 10.1 0.48 3.71e-21 Colorectal cancer; LIHC cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg05590025 chr7:65112418 INTS4L2 0.61 6.74 0.34 6.72e-11 Diabetic kidney disease; LIHC trans rs57221529 0.766 rs4081846 chr5:574019 G/A cg25482853 chr8:67687455 SGK3 0.62 6.25 0.32 1.22e-9 Lung disease severity in cystic fibrosis; LIHC cis rs1799949 0.931 rs9912203 chr17:41445145 A/G cg05368731 chr17:41323189 NBR1 -0.68 -11.24 -0.52 3.82e-25 Menopause (age at onset); LIHC trans rs13113518 0.812 rs7667741 chr4:56410788 T/C cg15358633 chr12:38710606 ALG10B 0.43 6.12 0.31 2.57e-9 Height; LIHC trans rs208520 0.674 rs207103 chr6:66795568 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs903552 1.000 rs11634912 chr15:102005510 A/G cg06707286 chr15:102010195 PCSK6 -0.44 -6.22 -0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs2067615 0.579 rs10507214 chr12:107194461 G/A cg15890332 chr12:107067104 RFX4 0.26 6.07 0.31 3.33e-9 Heart rate; LIHC cis rs4423214 1.000 rs11606631 chr11:71164121 C/A cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC cis rs3784262 0.654 rs4646568 chr15:58344290 A/G cg12031962 chr15:58353849 ALDH1A2 0.32 6.33 0.32 7.51e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg11494091 chr17:61959527 GH2 0.35 5.92 0.31 7.71e-9 Height; LIHC cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg08888203 chr3:10149979 C3orf24 0.59 6.93 0.35 2.13e-11 Alzheimer's disease; LIHC cis rs710216 0.879 rs710218 chr1:43427218 A/T cg03128534 chr1:43423976 SLC2A1 0.53 7.45 0.37 7.67e-13 Red cell distribution width; LIHC cis rs8062405 0.755 rs4788074 chr16:28593597 A/G cg07451762 chr16:28383216 NA -0.38 -6.79 -0.34 4.97e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg04286195 chr16:88099702 BANP 0.56 6.83 0.35 3.99e-11 Lung function (FEV1); LIHC cis rs734999 0.588 rs876938 chr1:2523212 G/C cg18854424 chr1:2615690 NA 0.33 7.27 0.37 2.48e-12 Ulcerative colitis; LIHC trans rs561341 1.000 rs4795667 chr17:30244443 T/C cg20587970 chr11:113659929 NA -0.73 -8.25 -0.41 3.56e-15 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg08219700 chr8:58056026 NA 0.5 6.33 0.32 7.49e-10 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.84 -0.54 2.51e-27 Alzheimer's disease; LIHC cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg23758822 chr17:41437982 NA 0.94 17.94 0.7 3.44e-51 Menopause (age at onset); LIHC cis rs7086627 0.515 rs4934189 chr10:82214792 C/T cg01528321 chr10:82214614 TSPAN14 0.56 7.84 0.39 5.83e-14 Post bronchodilator FEV1; LIHC cis rs7551222 0.752 rs12741351 chr1:204528256 G/A cg20240347 chr1:204465584 NA -0.34 -7.13 -0.36 5.86e-12 Schizophrenia; LIHC cis rs7772486 0.875 rs6914813 chr6:146397798 A/G cg05347473 chr6:146136440 FBXO30 0.37 5.72 0.3 2.31e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs765787 0.530 rs28526629 chr15:45540462 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.49 -0.38 5.88e-13 Uric acid levels; LIHC cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg18252515 chr7:66147081 NA -1.25 -16.5 -0.67 2.19e-45 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs35110281 0.807 rs2838326 chr21:45014315 C/T cg04455712 chr21:45112962 RRP1B 0.43 7.54 0.38 4.2e-13 Mean corpuscular volume; LIHC cis rs4888262 0.564 rs8050850 chr16:74582597 C/A cg01733217 chr16:74700730 RFWD3 0.79 15.25 0.64 2.04e-40 Testicular germ cell tumor; LIHC cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg11644478 chr21:40555479 PSMG1 0.84 10.61 0.5 6.35e-23 Cognitive function; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18126840 chr2:44689831 C2orf34 -0.28 -6.42 -0.33 4.61e-10 Calcium levels; LIHC cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg19539972 chr4:7069911 GRPEL1 0.67 9.66 0.46 1.08e-19 Monocyte percentage of white cells; LIHC cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg08219700 chr8:58056026 NA -0.44 -5.75 -0.3 2.02e-8 Developmental language disorder (linguistic errors); LIHC cis rs4878497 0.544 rs3205166 chr9:32459450 G/T cg14296220 chr9:32431791 ACO1 -0.46 -7.59 -0.38 3.07e-13 Inflammatory skin disease; LIHC cis rs2153535 0.601 rs2327091 chr6:8540369 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.2 0.41 4.88e-15 Motion sickness; LIHC cis rs8072100 0.967 rs4338849 chr17:45512483 A/G cg08085267 chr17:45401833 C17orf57 -0.57 -8.57 -0.42 3.54e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs35883536 0.647 rs2809795 chr1:101038345 A/G cg14515779 chr1:101123966 NA -0.42 -5.89 -0.3 9.19e-9 Monocyte count; LIHC cis rs17818399 0.716 rs62134741 chr2:46782189 G/A cg02822958 chr2:46747628 ATP6V1E2 0.5 7.28 0.37 2.28e-12 Height; LIHC cis rs77633900 0.614 rs12442966 chr15:76918290 G/T cg21673338 chr15:77095150 SCAPER 0.48 7.53 0.38 4.61e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs17776563 0.853 rs57761829 chr15:89150488 C/G cg05013243 chr15:89149849 MIR1179 0.42 6.83 0.35 3.78e-11 Thyroid hormone levels; LIHC trans rs9914544 0.545 rs2386403 chr17:18769600 A/G cg21372672 chr17:16614065 CCDC144A -0.28 -6.8 -0.35 4.77e-11 Educational attainment (years of education); LIHC cis rs6547741 0.935 rs6547738 chr2:27852637 A/G cg27432699 chr2:27873401 GPN1 0.78 12.92 0.57 2.28e-31 Oral cavity cancer; LIHC trans rs10411161 0.702 rs79180893 chr19:52395615 A/G cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs965469 0.779 rs6037528 chr20:3260978 A/G cg25506879 chr20:3388711 C20orf194 -0.53 -6.53 -0.33 2.41e-10 IFN-related cytopenia; LIHC cis rs782590 0.738 rs4312532 chr2:55812061 A/G cg18811423 chr2:55921094 PNPT1 -0.58 -8.96 -0.44 2.21e-17 Metabolic syndrome; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.17 -0.32 1.93e-9 Total body bone mineral density; LIHC cis rs561341 1.000 rs2344312 chr17:30243583 G/T cg13647721 chr17:30228624 UTP6 0.75 7.79 0.39 8.35e-14 Hip circumference adjusted for BMI; LIHC cis rs67460515 0.563 rs16831981 chr3:160897780 T/C cg17135325 chr3:160939158 NMD3 0.57 8.45 0.42 8.5e-16 Parkinson's disease; LIHC cis rs782590 1.000 rs782590 chr2:55843413 C/T cg03859395 chr2:55845619 SMEK2 0.96 16.77 0.67 1.72e-46 Metabolic syndrome; LIHC cis rs7534824 0.625 rs12565777 chr1:101485794 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.75 6.98 0.35 1.57e-11 Refractive astigmatism; LIHC cis rs1799949 1.000 rs915945 chr17:41179864 C/T cg23758822 chr17:41437982 NA 0.93 17.15 0.68 5.31e-48 Menopause (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16202803 chr2:240014758 HDAC4 0.51 7.66 0.38 1.96e-13 Longevity; LIHC trans rs2243480 1.000 rs35825738 chr7:65318027 A/G cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs12824058 0.798 rs7968728 chr12:130804696 T/A cg26677194 chr12:130822605 PIWIL1 0.49 6.54 0.33 2.29e-10 Menopause (age at onset); LIHC cis rs7572733 0.534 rs700685 chr2:198715972 A/G cg10820045 chr2:198174542 NA 0.49 7.46 0.37 6.98e-13 Dermatomyositis; LIHC cis rs12220238 0.841 rs11000942 chr10:76025256 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.47 0.33 3.47e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs734999 0.588 rs745368 chr1:2524205 C/T cg18854424 chr1:2615690 NA 0.33 7.27 0.37 2.48e-12 Ulcerative colitis; LIHC cis rs208520 0.690 rs1738970 chr6:66809491 T/G cg07460842 chr6:66804631 NA -0.84 -9.33 -0.45 1.38e-18 Exhaled nitric oxide output; LIHC cis rs8067354 0.872 rs7224006 chr17:57896338 C/T cg13753209 chr17:57696993 CLTC -0.59 -8.95 -0.44 2.27e-17 Hemoglobin concentration; LIHC cis rs2153535 0.580 rs9505455 chr6:8478622 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg08280861 chr8:58055591 NA 0.54 6.22 0.32 1.49e-9 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.673 rs2269915 chr17:29233344 C/T cg13385521 chr17:29058706 SUZ12P 0.84 8.15 0.4 7.08e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2455799 0.613 rs2470537 chr3:15716898 C/T cg12698662 chr3:15914712 MIR563 -0.37 -6.68 -0.34 9.79e-11 Mean platelet volume; LIHC cis rs904251 0.523 rs10807184 chr6:37483713 C/T cg08126542 chr6:37504118 NA -0.37 -6.27 -0.32 1.09e-9 Cognitive performance; LIHC cis rs61990749 0.597 rs6574391 chr14:78208121 G/A cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.74 -0.39 1.13e-13 Fibroblast growth factor basic levels; LIHC cis rs36051895 0.623 rs6476955 chr9:5256533 C/G cg02405213 chr9:5042618 JAK2 -0.65 -10.89 -0.51 6.75e-24 Pediatric autoimmune diseases; LIHC cis rs288342 0.832 rs288300 chr2:183657279 C/T cg02625481 chr2:183667124 NA -0.29 -6.04 -0.31 3.99e-9 Recurrent major depressive disorder; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg14733936 chr2:70476139 TIA1 0.42 6.49 0.33 3.05e-10 Calcium levels; LIHC cis rs739401 0.611 rs494427 chr11:3048140 A/G cg25174290 chr11:3078921 CARS 0.62 9.38 0.45 9.42e-19 Longevity; LIHC cis rs208520 0.560 rs2351880 chr6:66863707 G/A cg07460842 chr6:66804631 NA -0.77 -8.19 -0.4 5.25e-15 Exhaled nitric oxide output; LIHC cis rs7927771 0.864 rs2293577 chr11:47437202 C/T cg20135002 chr11:47629003 NA 0.56 9.44 0.45 5.99e-19 Subjective well-being; LIHC cis rs10792665 0.640 rs7947047 chr11:82620556 A/G cg24227371 chr11:82718527 RAB30 -0.27 -6.13 -0.31 2.41e-9 Obesity-related traits; LIHC cis rs9381040 0.655 rs9381032 chr6:41044986 A/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.16 -0.32 2.05e-9 Alzheimer's disease (late onset); LIHC cis rs4853012 0.838 rs60964317 chr2:74343423 A/T cg20891558 chr2:74357851 NA 0.81 16.67 0.67 4.27e-46 Gestational age at birth (maternal effect); LIHC cis rs2033908 0.620 rs1992334 chr11:12851645 C/T cg25843174 chr11:12811716 TEAD1 -0.32 -7.21 -0.36 3.55e-12 Sitting height ratio; LIHC cis rs4423214 0.879 rs4945008 chr11:71221248 A/G cg05163923 chr11:71159392 DHCR7 0.89 13.42 0.59 2.69e-33 Vitamin D levels; LIHC cis rs1046896 0.553 rs9893885 chr17:80837107 C/T cg02711726 chr17:80685570 FN3KRP -0.45 -8.22 -0.41 4.17e-15 Glycated hemoglobin levels; LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09896403 chr22:24110173 CHCHD10 0.49 6.16 0.32 2.06e-9 Hepatitis; LIHC cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.41 0.45 7.44e-19 Bipolar disorder; LIHC cis rs798554 0.634 rs6978692 chr7:2857411 C/T cg13628971 chr7:2884303 GNA12 0.44 6.94 0.35 2.03e-11 Height; LIHC cis rs908922 0.676 rs10888492 chr1:152499908 G/C cg23254163 chr1:152506842 NA 0.22 5.81 0.3 1.4e-8 Hair morphology; LIHC cis rs6598955 0.724 rs4659420 chr1:26614333 G/A cg00852783 chr1:26633632 UBXN11 0.5 8.36 0.41 1.58e-15 Obesity-related traits; LIHC cis rs875971 0.660 rs10215132 chr7:66054406 C/A cg00343986 chr7:65444356 GUSB -0.38 -5.78 -0.3 1.64e-8 Aortic root size; LIHC trans rs6934970 1.000 rs12213231 chr6:113072928 A/G cg20627988 chr10:133946881 JAKMIP3 0.45 6.23 0.32 1.35e-9 Bipolar disorder (body mass index interaction); LIHC cis rs3809566 0.637 rs8026047 chr15:63323347 C/G cg21584241 chr15:63341463 TPM1 0.38 5.91 0.3 8.13e-9 Platelet count; LIHC cis rs2540917 0.728 rs243079 chr2:60615028 A/C cg00543073 chr2:60773386 BCL11A -0.31 -6.12 -0.31 2.53e-9 Mean corpuscular volume; LIHC cis rs5769765 0.862 rs9616381 chr22:50312382 G/A cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs7927592 0.956 rs7124078 chr11:68298633 G/T cg16797656 chr11:68205561 LRP5 0.52 8.27 0.41 2.96e-15 Total body bone mineral density; LIHC cis rs2302190 0.882 rs7213415 chr17:56672433 C/G cg12560992 chr17:57184187 TRIM37 0.69 8.91 0.43 3.17e-17 Vitamin D levels; LIHC cis rs1055129 0.655 rs3744006 chr17:73838816 G/A cg10935138 chr17:73851978 WBP2 0.46 7.12 0.36 6.6e-12 White matter hyperintensity burden; LIHC cis rs8180040 0.726 rs6774733 chr3:46991241 G/A cg16586182 chr3:47516702 SCAP -0.45 -8.18 -0.4 5.57e-15 Colorectal cancer; LIHC cis rs2839186 0.500 rs13049893 chr21:47707054 C/T cg09417038 chr21:47716443 C21orf57 -0.68 -10.35 -0.49 5.21e-22 Testicular germ cell tumor; LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.13 0.4 8.12e-15 Height; LIHC cis rs9549367 0.789 rs34568744 chr13:113894564 G/T cg00898013 chr13:113819073 PROZ -0.42 -7.37 -0.37 1.33e-12 Platelet distribution width; LIHC cis rs919433 0.679 rs6741314 chr2:198526088 G/A cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs4474465 0.850 rs4944203 chr11:78220629 A/C cg02023728 chr11:77925099 USP35 -0.33 -5.84 -0.3 1.2e-8 Alzheimer's disease (survival time); LIHC trans rs1814175 0.645 rs1818895 chr11:50031523 G/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs1144333 1.000 rs17097836 chr1:76462006 T/A cg03433033 chr1:76189801 ACADM 0.51 7.48 0.38 6.2800000000000005e-13 Attention function in attention deficit hyperactive disorder; LIHC trans rs11039798 0.557 rs4441015 chr11:49027070 A/G cg15704280 chr7:45808275 SEPT13 0.61 6.88 0.35 2.88e-11 Axial length; LIHC cis rs7188697 0.922 rs7199856 chr16:58584772 A/C cg02549819 chr16:58548995 SETD6 -0.52 -8.16 -0.4 6.7e-15 QT interval; LIHC cis rs858239 0.539 rs10254544 chr7:23220235 T/C cg18081818 chr7:23246105 NA -0.41 -5.95 -0.31 6.56e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs57221529 0.709 rs72703034 chr5:577101 C/T cg09021430 chr5:549028 NA -0.45 -9.08 -0.44 9.1e-18 Lung disease severity in cystic fibrosis; LIHC cis rs12477438 0.765 rs6754843 chr2:99680485 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs4970988 0.527 rs12067556 chr1:150614535 G/A cg13175981 chr1:150552382 MCL1 -0.5 -6.96 -0.35 1.74e-11 Urate levels; LIHC cis rs754466 0.605 rs10824578 chr10:79578244 G/C cg17075019 chr10:79541650 NA -0.83 -15.42 -0.64 4.27e-41 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12701220 0.655 rs6955290 chr7:1151066 A/G cg04498913 chr7:1135747 C7orf50 -0.42 -6.62 -0.34 1.37e-10 Bronchopulmonary dysplasia; LIHC cis rs11122272 0.735 rs2749699 chr1:231520279 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC trans rs7618501 1.000 rs34614773 chr3:49753003 T/G cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs6840360 0.571 rs12650655 chr4:152556075 G/A cg22705602 chr4:152727874 NA -0.31 -6.14 -0.32 2.29e-9 Intelligence (multi-trait analysis); LIHC cis rs9828933 0.626 rs73119018 chr3:63975328 A/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.81 -9.99 -0.48 8.43e-21 Type 2 diabetes; LIHC cis rs12474201 0.894 rs34401107 chr2:46972768 A/C cg06386533 chr2:46925753 SOCS5 0.69 8.13 0.4 7.81e-15 Height; LIHC cis rs2050392 0.517 rs602097 chr10:30747546 C/T cg25182066 chr10:30743637 MAP3K8 -0.72 -11.26 -0.52 3.05e-25 Inflammatory bowel disease; LIHC cis rs7647973 0.696 rs3087866 chr3:49054692 A/G cg20833759 chr3:49053208 WDR6;DALRD3 0.52 6.17 0.32 1.88e-9 Menarche (age at onset); LIHC cis rs4332037 0.722 rs55934553 chr7:1914059 T/C cg23422044 chr7:1970798 MAD1L1 -0.68 -10.5 -0.49 1.59e-22 Bipolar disorder; LIHC cis rs1003719 0.582 rs2835634 chr21:38528270 T/A cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.07 -0.51 1.46e-24 Eye color traits; LIHC cis rs11583043 0.918 rs6577216 chr1:101409972 C/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.19 0.32 1.69e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7607369 0.680 rs533760 chr2:219381405 T/C cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs10492096 0.947 rs10849483 chr12:6635374 G/A cg13857086 chr12:6580257 VAMP1 0.57 6.07 0.31 3.48e-9 Hip geometry; LIHC cis rs9918079 0.580 rs13120905 chr4:15612288 A/T cg24225360 chr4:15471699 CC2D2A 0.38 6.07 0.31 3.46e-9 Obesity-related traits; LIHC cis rs4700695 0.764 rs36300 chr5:65348153 C/T cg21114390 chr5:65439923 SFRS12 0.45 5.75 0.3 2e-8 Facial morphology (factor 19); LIHC cis rs7296418 0.961 rs1727307 chr12:123575742 A/G cg05973401 chr12:123451056 ABCB9 0.49 7.58 0.38 3.28e-13 Platelet count; LIHC cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg11766577 chr21:47581405 C21orf56 -0.45 -7.52 -0.38 4.99e-13 Testicular germ cell tumor; LIHC cis rs2361718 0.500 rs8068856 chr17:78100731 A/G cg09238746 chr17:78121135 EIF4A3 -0.73 -11.64 -0.53 1.28e-26 Yeast infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06465160 chr1:25071620 CLIC4 0.47 6.56 0.33 1.97e-10 Pancreatic cancer; LIHC cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.09 0.31 2.96e-9 Menopause (age at onset); LIHC cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg03060546 chr3:49711283 APEH 0.44 6.56 0.33 1.94e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs17253792 0.822 rs10139905 chr14:56170031 T/C cg01858014 chr14:56050164 KTN1 -0.63 -6.99 -0.35 1.42e-11 Putamen volume; LIHC trans rs6600671 1.000 rs4844607 chr1:121184059 C/T cg08727972 chr1:148025634 NBPF14 -0.4 -6.11 -0.31 2.68e-9 Hip geometry; LIHC cis rs798554 0.797 rs798487 chr7:2802943 G/A cg13628971 chr7:2884303 GNA12 0.52 7.68 0.38 1.69e-13 Height; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12268410 chr8:110346451 ENY2;NUDCD1 -0.43 -6.65 -0.34 1.15e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs1005277 0.579 rs2472178 chr10:38384750 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.37 -0.33 6.02e-10 Extrinsic epigenetic age acceleration; LIHC cis rs735396 1.000 rs1169310 chr12:121439433 G/A cg02403541 chr12:121454288 C12orf43 0.47 8.27 0.41 3.07e-15 N-glycan levels; LIHC cis rs12477438 0.798 rs6761570 chr2:99577276 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.07 -14.82 -0.63 1.03e-38 Chronic sinus infection; LIHC cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg26939375 chr7:64535504 NA -0.46 -7.03 -0.36 1.16e-11 Aortic root size; LIHC cis rs7703051 0.585 rs918623 chr5:74596682 A/C cg19683494 chr5:74908142 NA 0.69 9.74 0.47 5.91e-20 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs2274273 0.934 rs2341621 chr14:55726425 C/T cg04306507 chr14:55594613 LGALS3 0.32 5.97 0.31 5.93e-9 Protein biomarker; LIHC cis rs317689 0.718 rs315130 chr12:69761444 T/C cg22834771 chr12:69754056 YEATS4 -0.38 -5.83 -0.3 1.27e-8 Response to diuretic therapy; LIHC cis rs4891159 0.584 rs2848958 chr18:74157068 C/T cg24786174 chr18:74118243 ZNF516 0.81 15.71 0.65 3.06e-42 Longevity; LIHC cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg07424592 chr7:64974309 NA 0.8 9.21 0.45 3.38e-18 Diabetic kidney disease; LIHC cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg06481639 chr22:41940642 POLR3H -0.71 -7.08 -0.36 8.3e-12 Vitiligo; LIHC cis rs919433 0.647 rs6741205 chr2:198525997 G/C cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7772486 0.754 rs6910790 chr6:146255330 G/A cg05347473 chr6:146136440 FBXO30 -0.37 -5.91 -0.3 8.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7944584 1.000 rs7944584 chr11:47336320 A/T cg20307385 chr11:47447363 PSMC3 0.59 6.11 0.31 2.65e-9 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs7534824 0.582 rs41312670 chr1:101443431 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.38 0.37 1.22e-12 Refractive astigmatism; LIHC cis rs10489202 1.000 rs12408205 chr1:167982332 A/G cg24449463 chr1:168025552 DCAF6 -0.51 -6.4 -0.33 5.12e-10 Schizophrenia; LIHC cis rs916888 0.821 rs199505 chr17:44859410 A/G cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7572733 0.534 rs700688 chr2:198723833 A/G cg03934865 chr2:198174659 NA -0.47 -6.87 -0.35 3.02e-11 Dermatomyositis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13847120 chr17:43224789 HEXIM1 0.43 6.42 0.33 4.48e-10 Lung function (FEV1/FVC); LIHC cis rs12431939 1.000 rs7160729 chr14:51637241 C/T cg23942311 chr14:51606299 NA -0.35 -5.84 -0.3 1.21e-8 Cancer; LIHC cis rs6973256 0.568 rs7800126 chr7:133521356 A/C cg03336402 chr7:133662267 EXOC4 -0.38 -5.83 -0.3 1.25e-8 Intelligence (multi-trait analysis); LIHC cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg13271783 chr10:134563150 INPP5A -0.53 -6.52 -0.33 2.6e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12477438 0.520 rs34252185 chr2:99737646 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC cis rs2439831 0.850 rs524417 chr15:43772374 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.54 0.59 9.52e-34 Lung cancer in ever smokers; LIHC cis rs4423214 1.000 rs2282620 chr11:71183477 C/T cg05163923 chr11:71159392 DHCR7 0.8 12.07 0.55 3.62e-28 Vitamin D levels; LIHC cis rs372883 0.648 rs2832296 chr21:30741454 C/T cg08807101 chr21:30365312 RNF160 -0.53 -6.29 -0.32 9.88e-10 Pancreatic cancer; LIHC cis rs2153535 0.580 rs9406167 chr6:8502852 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.42 0.41 1.07e-15 Motion sickness; LIHC cis rs17685 0.753 rs6953665 chr7:75769049 C/T cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1000083 0.748 rs3108525 chr5:96625961 A/G ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs597539 0.652 rs544370 chr11:68653232 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.79 12.44 0.56 1.47e-29 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg23758822 chr17:41437982 NA 0.93 17.53 0.69 1.49e-49 Menopause (age at onset); LIHC cis rs4819052 0.851 rs1056101 chr21:46678702 C/G cg22633049 chr21:46681294 NA -0.37 -6.31 -0.32 8.57e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7927592 0.913 rs10896347 chr11:68353127 G/A cg16797656 chr11:68205561 LRP5 0.5 7.8 0.39 7.44e-14 Total body bone mineral density; LIHC cis rs9303401 0.573 rs34097494 chr17:57171917 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.99 0.54 6.63e-28 Cognitive test performance; LIHC cis rs9911578 1.000 rs304270 chr17:56802141 A/G cg05425664 chr17:57184151 TRIM37 0.59 8.8 0.43 6.94e-17 Intelligence (multi-trait analysis); LIHC cis rs11628318 0.614 rs4906254 chr14:103209153 C/T cg12046867 chr14:103022105 NA -0.42 -6.62 -0.34 1.39e-10 Platelet count; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05195393 chr14:69865263 SLC39A9;ERH 0.34 6.6 0.34 1.55e-10 Calcium levels; LIHC cis rs1707322 0.721 rs11211181 chr1:46236800 C/T cg06784218 chr1:46089804 CCDC17 0.39 7.34 0.37 1.57e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs847649 0.699 rs10242028 chr7:102527785 C/G cg18108683 chr7:102477205 FBXL13 -0.48 -7.41 -0.37 1.03e-12 Morning vs. evening chronotype; LIHC cis rs2839186 0.739 rs7282763 chr21:47696800 C/T cg00612595 chr21:47717864 NA -0.37 -5.99 -0.31 5.44e-9 Testicular germ cell tumor; LIHC cis rs847851 0.617 rs9394265 chr6:34950274 T/G cg13137465 chr6:34857473 ANKS1A 0.67 7.45 0.37 7.92e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs2304069 0.507 rs13167061 chr5:149388624 T/G cg12661370 chr5:149340060 SLC26A2 0.55 8.24 0.41 3.7e-15 HIV-1 control; LIHC cis rs35306767 0.903 rs7077278 chr10:911291 A/G cg26597838 chr10:835615 NA -1.21 -14.69 -0.62 3.13e-38 Eosinophil percentage of granulocytes; LIHC cis rs4953318 0.619 rs10183887 chr2:46361808 T/A cg12428440 chr2:46370979 PRKCE 0.46 6.33 0.32 7.73e-10 Red blood cell count;Hematocrit;Red blood cell traits; LIHC cis rs7927592 0.871 rs17603185 chr11:68376241 C/T cg16797656 chr11:68205561 LRP5 0.49 7.71 0.38 1.39e-13 Total body bone mineral density; LIHC cis rs3806843 0.933 rs10069930 chr5:140163328 T/A cg19875535 chr5:140030758 IK 0.37 5.94 0.31 6.91e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs796364 0.806 rs203769 chr2:200900866 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -7.32 -0.37 1.73e-12 Schizophrenia; LIHC cis rs1113500 0.933 rs10785834 chr1:108639101 A/C cg06207961 chr1:108661230 NA 0.37 7.28 0.37 2.3e-12 Growth-regulated protein alpha levels; LIHC cis rs7582720 0.832 rs115194657 chr2:203829284 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs875971 0.895 rs1974769 chr7:65950614 G/A cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs17666538 0.535 rs1669613 chr8:617565 G/C cg07234876 chr8:600039 NA 0.93 7.33 0.37 1.64e-12 IgG glycosylation; LIHC cis rs4665809 1.000 rs4665809 chr2:26251361 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.7 8.55 0.42 4.27e-16 Gut microbiome composition (summer); LIHC cis rs2303759 0.918 rs4802597 chr19:49872085 C/T cg22307029 chr19:49891270 CCDC155 0.55 8.78 0.43 8.11e-17 Multiple sclerosis; LIHC cis rs16828019 0.789 rs36084778 chr1:41479538 A/G cg03962019 chr1:41807865 NA 0.5 7.09 0.36 7.76e-12 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg20607798 chr8:58055168 NA 0.73 8.14 0.4 7.32e-15 Developmental language disorder (linguistic errors); LIHC trans rs1268083 0.546 rs9398785 chr6:126057748 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.57 -9.07 -0.44 9.2e-18 Migraine; LIHC cis rs7200543 1.000 rs16966947 chr16:15141045 T/C cg07549590 chr16:15018862 NA -0.32 -5.92 -0.31 7.68e-9 Glycerophospholipid levels;Metabolic traits;Body mass index;Triglyceride levels; LIHC cis rs644799 0.511 rs12791736 chr11:95475399 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.78 12.22 0.55 9.81e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7586673 0.964 rs34444368 chr2:161954217 G/A cg22496339 chr2:162101262 NA 0.7 10.64 0.5 4.96e-23 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17096262 chr10:29759227 SVIL 0.4 6.15 0.32 2.13e-9 Longevity; LIHC cis rs8180040 0.603 rs9854790 chr3:47101306 T/G cg16586182 chr3:47516702 SCAP -0.49 -8.75 -0.43 9.86e-17 Colorectal cancer; LIHC cis rs5850 0.557 rs10270788 chr7:23189000 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.96 0.35 1.71e-11 Blood protein levels; LIHC cis rs34779708 0.897 rs16935880 chr10:35415468 C/G cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3812831 0.695 rs913526 chr13:114928946 G/C cg06611532 chr13:114900021 NA 0.43 7.76 0.39 1.02e-13 Schizophrenia; LIHC cis rs922107 0.738 rs10922665 chr1:90036508 G/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.67 -0.38 1.79e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs4561483 0.583 rs9925010 chr16:11956668 A/G cg08843971 chr16:11963173 GSPT1 0.39 7.28 0.37 2.36e-12 Testicular germ cell tumor; LIHC cis rs9916302 0.861 rs11078913 chr17:37671714 G/T cg03013999 chr17:37608204 MED1 0.35 5.75 0.3 1.94e-8 Glomerular filtration rate (creatinine); LIHC cis rs3806933 0.522 rs34962120 chr5:110446091 G/A cg04022379 chr5:110408740 TSLP 0.57 9.12 0.44 6.52e-18 Eosinophilic esophagitis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11361691 chr3:57993876 FLNB 0.44 6.17 0.32 1.91e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg01765077 chr12:122356316 WDR66 0.58 7.74 0.39 1.17e-13 Mean corpuscular volume; LIHC trans rs7246657 0.943 rs4803460 chr19:37885228 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs7904368 0.806 rs7099178 chr10:16862578 C/G cg14835575 chr10:16859367 RSU1 0.66 9.09 0.44 8.18e-18 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs1005277 0.579 rs2472181 chr10:38386764 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg00149659 chr3:10157352 C3orf10 0.66 6.76 0.34 5.88e-11 Alzheimer's disease; LIHC cis rs1862618 0.853 rs252910 chr5:56192983 G/A cg18230493 chr5:56204884 C5orf35 -0.49 -6.7 -0.34 8.7e-11 Initial pursuit acceleration; LIHC cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg21724239 chr8:58056113 NA 0.62 7.9 0.39 3.77e-14 Developmental language disorder (linguistic errors); LIHC cis rs754466 0.580 rs2579177 chr10:79529245 C/T cg17075019 chr10:79541650 NA -0.74 -11.31 -0.52 2.01e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7197653 0.748 rs8063446 chr16:68344363 A/C cg09835421 chr16:68378352 PRMT7 -0.84 -7.91 -0.39 3.63e-14 Magnesium levels; LIHC cis rs2153535 0.580 rs4140586 chr6:8503192 A/G cg07606381 chr6:8435919 SLC35B3 0.8 11.97 0.54 8.17e-28 Motion sickness; LIHC cis rs2710642 0.821 rs2710639 chr2:63138963 C/T cg17519650 chr2:63277830 OTX1 0.43 6.65 0.34 1.2e-10 LDL cholesterol levels;LDL cholesterol; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg00696901 chr1:113933133 MAGI3 -0.48 -6.16 -0.32 2.06e-9 Hepatitis; LIHC cis rs709400 0.663 rs9671911 chr14:103967343 T/C cg26031613 chr14:104095156 KLC1 0.73 9.15 0.44 5.37e-18 Body mass index; LIHC cis rs10504229 0.593 rs2317990 chr8:58024168 G/T cg02290350 chr8:58132656 NA 0.3 6.85 0.35 3.41e-11 Developmental language disorder (linguistic errors); LIHC cis rs66887589 0.616 rs11731675 chr4:120212514 T/C cg09307838 chr4:120376055 NA 0.55 8.1 0.4 9.62e-15 Diastolic blood pressure; LIHC cis rs4665809 0.818 rs35413760 chr2:26267137 C/A cg26119090 chr2:26468346 HADHA;HADHB 0.7 7.6 0.38 2.83e-13 Gut microbiome composition (summer); LIHC cis rs11758351 0.715 rs75390741 chr6:26209784 A/T cg16070018 chr6:26224392 HIST1H3E 0.6 7.26 0.37 2.59e-12 Gout;Renal underexcretion gout; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15025054 chr1:212964885 TATDN3;NSL1 0.49 6.69 0.34 8.91e-11 Pancreatic cancer; LIHC cis rs4919694 1.000 rs112240253 chr10:104753726 C/T cg04362960 chr10:104952993 NT5C2 1.09 7.82 0.39 6.73e-14 Arsenic metabolism; LIHC cis rs28647808 0.881 rs7029256 chr9:136263655 T/C cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC trans rs259842 0.800 rs6725456 chr2:180718419 C/T cg12651014 chr10:32735292 CCDC7 0.44 6.08 0.31 3.2e-9 Blood protein levels; LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.0 -0.31 5.01e-9 Diastolic blood pressure; LIHC cis rs11031096 0.503 rs10835604 chr11:4109709 A/T cg18678763 chr11:4115507 RRM1 -0.56 -8.15 -0.4 7.02e-15 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs3812111 0.641 rs9387383 chr6:116422847 A/G cg08036074 chr6:116424633 NT5DC1 -0.61 -11.32 -0.52 1.9e-25 Age-related macular degeneration; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.85 -0.35 3.51e-11 Diastolic blood pressure; LIHC cis rs1355223 1.000 rs12792532 chr11:34765782 G/T cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.36 -0.33 6.37e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs3096299 0.933 rs2965824 chr16:89455306 A/G cg00750074 chr16:89608354 SPG7 -0.37 -5.75 -0.3 2.01e-8 Multiple myeloma (IgH translocation); LIHC cis rs7927771 0.864 rs4752999 chr11:47428565 C/T cg20307385 chr11:47447363 PSMC3 -0.48 -6.28 -0.32 1.03e-9 Subjective well-being; LIHC cis rs1005277 0.579 rs2472178 chr10:38384750 T/C cg00409905 chr10:38381863 ZNF37A -0.59 -10.31 -0.49 6.75e-22 Extrinsic epigenetic age acceleration; LIHC cis rs2067615 0.524 rs4964186 chr12:107080235 C/T cg15890332 chr12:107067104 RFX4 0.27 6.42 0.33 4.66e-10 Heart rate; LIHC cis rs9420 0.961 rs7121169 chr11:57452543 G/A cg19752551 chr11:57585705 CTNND1 -0.53 -7.39 -0.37 1.16e-12 Schizophrenia; LIHC cis rs12497850 0.931 rs12493289 chr3:48905161 G/A cg06212747 chr3:49208901 KLHDC8B 0.57 7.32 0.37 1.84e-12 Parkinson's disease; LIHC cis rs2467099 0.786 rs1135889 chr17:73926121 C/A cg08125733 chr17:73851984 WBP2 0.46 5.8 0.3 1.54e-8 Systolic blood pressure; LIHC cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg16405210 chr4:1374714 KIAA1530 0.44 6.53 0.33 2.32e-10 Obesity-related traits; LIHC cis rs68170813 0.559 rs7981 chr7:106843133 G/C cg02696742 chr7:106810147 HBP1 -0.54 -6.06 -0.31 3.64e-9 Coronary artery disease; LIHC cis rs7208859 0.725 rs9910051 chr17:29161202 A/T cg13385521 chr17:29058706 SUZ12P 0.75 7.62 0.38 2.44e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4862750 0.914 rs1991256 chr4:187875330 A/G cg11301795 chr4:187892539 NA -0.26 -6.78 -0.34 5.43e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1538970 0.924 rs11211117 chr1:45930246 C/T cg24296786 chr1:45957014 TESK2 -0.51 -7.45 -0.37 7.79e-13 Platelet count; LIHC cis rs8081395 0.836 rs1295926 chr17:57909373 A/G cg13753209 chr17:57696993 CLTC -0.47 -7.23 -0.36 3.16e-12 White blood cell count; LIHC cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg06481639 chr22:41940642 POLR3H -0.64 -6.55 -0.33 2.08e-10 Vitiligo; LIHC cis rs722599 0.748 rs929579 chr14:75330697 C/T cg11812906 chr14:75593930 NEK9 -0.42 -6.46 -0.33 3.54e-10 IgG glycosylation; LIHC cis rs7216064 1.000 rs6504543 chr17:65837659 T/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.66 -0.46 1.12e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs2727020 0.521 rs1909220 chr11:49572109 T/C cg18944383 chr4:111397179 ENPEP 0.35 8.17 0.4 6.09e-15 Coronary artery disease; LIHC cis rs1555322 0.530 rs2275275 chr20:33872311 G/C cg17927777 chr20:33865990 NA 0.56 6.56 0.33 2.01e-10 Attention deficit hyperactivity disorder; LIHC cis rs7618501 0.540 rs11130241 chr3:50131459 A/T cg21467203 chr3:49911342 NA 0.43 7.54 0.38 4.31e-13 Intelligence (multi-trait analysis); LIHC cis rs1198430 0.636 rs1009590 chr1:23823798 C/G cg13183780 chr1:23809682 ASAP3 0.54 7.17 0.36 4.72e-12 Total cholesterol levels; LIHC cis rs7927592 0.731 rs7108376 chr11:68347870 A/G cg16797656 chr11:68205561 LRP5 -0.5 -8.83 -0.43 5.35e-17 Total body bone mineral density; LIHC cis rs875971 0.577 rs35072105 chr7:65609817 A/G cg14393609 chr7:65229607 NA -0.41 -6.1 -0.31 2.8e-9 Aortic root size; LIHC cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 9.19 0.45 3.84e-18 Platelet count; LIHC cis rs10870270 0.957 rs7074604 chr10:133740373 G/C cg26149184 chr10:133730230 NA 0.47 7.39 0.37 1.16e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2637030 0.559 rs424955 chr5:52902895 A/G cg06476337 chr5:52856530 NDUFS4 0.38 6.08 0.31 3.17e-9 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs651907 0.557 rs7651721 chr3:101393583 C/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.69 11.03 0.51 2.04e-24 Colorectal cancer; LIHC cis rs12908161 0.959 rs17534709 chr15:85314397 G/C cg17507749 chr15:85114479 UBE2QP1 0.64 7.31 0.37 1.92e-12 Schizophrenia; LIHC cis rs4746818 1.000 rs4284308 chr10:70884861 C/T cg11621586 chr10:70884670 VPS26A 0.87 14.3 0.61 1.12e-36 Left atrial antero-posterior diameter; LIHC cis rs9388451 0.874 rs3734634 chr6:126111800 G/A cg05901451 chr6:126070800 HEY2 -0.74 -17.05 -0.68 1.33e-47 Brugada syndrome; LIHC cis rs7716219 0.751 rs6869221 chr5:54881212 G/T cg14753740 chr5:54468940 CDC20B;MIR449C 0.42 5.88 0.3 9.69e-9 Height; LIHC cis rs4742903 0.935 rs6479225 chr9:106940330 T/C cg14250997 chr9:106856677 SMC2 0.35 5.92 0.3 7.73e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs858239 0.699 rs858260 chr7:23212934 G/T cg18081818 chr7:23246105 NA -0.41 -5.92 -0.31 7.69e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs155076 0.938 rs9509630 chr13:21844314 G/A cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.3e-30 White matter hyperintensity burden; LIHC cis rs66573146 0.831 rs68111914 chr4:6986677 C/T cg00086871 chr4:6988644 TBC1D14 0.79 5.86 0.3 1.08e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs3818285 0.556 rs944966 chr10:111658334 C/G cg00817464 chr10:111662876 XPNPEP1 -0.53 -8.47 -0.42 7.32e-16 Superior crus of antihelix expression; LIHC cis rs7552167 0.925 rs3932664 chr1:24511663 G/T cg01960748 chr1:24522592 NA -0.56 -7.59 -0.38 3.05e-13 Psoriasis vulgaris; LIHC cis rs546131 0.642 rs58210900 chr11:34838047 A/G cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.49 -0.33 3.05e-10 Lung disease severity in cystic fibrosis; LIHC trans rs916888 0.821 rs199499 chr17:44865498 C/T cg13957321 chr17:43675089 NA 0.53 7.14 0.36 5.62e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11098499 0.731 rs9995026 chr4:120490499 T/A cg09307838 chr4:120376055 NA 0.75 11.73 0.54 5.96e-27 Corneal astigmatism; LIHC trans rs3780486 0.846 rs6476399 chr9:33123013 A/G cg04842962 chr6:43655489 MRPS18A 1.05 24.75 0.8 3.19e-78 IgG glycosylation; LIHC cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg02359409 chr6:42947317 PEX6 -0.44 -5.94 -0.31 6.85e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7103648 0.966 rs874896 chr11:47418953 C/G cg20307385 chr11:47447363 PSMC3 1.01 17.31 0.68 1.16e-48 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg13607699 chr17:42295918 UBTF 0.44 7.05 0.36 9.82e-12 Total body bone mineral density; LIHC cis rs8049603 0.524 rs4967967 chr16:23091719 A/T cg16484020 chr16:23217411 SCNN1G -0.23 -5.77 -0.3 1.82e-8 Multiple sclerosis; LIHC cis rs7264396 0.561 rs6120993 chr20:34185161 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.57 -7.85 -0.39 5.29e-14 Total cholesterol levels; LIHC cis rs8067354 0.645 rs56236317 chr17:57822125 C/T cg13753209 chr17:57696993 CLTC 0.73 11.52 0.53 3.71e-26 Hemoglobin concentration; LIHC cis rs9457247 0.588 rs35171809 chr6:167432766 A/G cg23791538 chr6:167370224 RNASET2 -0.53 -8.66 -0.42 1.95e-16 Crohn's disease; LIHC trans rs801193 0.904 rs4718403 chr7:66242729 C/G cg26939375 chr7:64535504 NA 0.43 6.82 0.35 4.11e-11 Aortic root size; LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg08677398 chr8:58056175 NA 0.4 6.02 0.31 4.51e-9 Developmental language disorder (linguistic errors); LIHC cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg08645402 chr16:4508243 NA 0.41 7.66 0.38 1.89e-13 Schizophrenia; LIHC cis rs600806 0.888 rs3853498 chr1:109860144 T/C cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.92 -0.3 7.78e-9 Intelligence (multi-trait analysis); LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg06558623 chr16:89946397 TCF25 1.0 15.58 0.64 9.86e-42 Skin colour saturation; LIHC cis rs11663156 0.921 rs56054126 chr18:50920599 T/G cg24270629 chr18:50823537 DCC -0.48 -6.56 -0.33 2.05e-10 Intelligence (multi-trait analysis); LIHC cis rs74417235 0.639 rs2396994 chr5:154052750 A/T cg19735590 chr5:154026979 NA -0.48 -5.94 -0.31 6.93e-9 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs6486730 1.000 rs6486730 chr12:129275027 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.35 -6.2 -0.32 1.59e-9 Systemic lupus erythematosus; LIHC cis rs2274273 0.840 rs10136596 chr14:55836773 A/G cg01864836 chr14:55583639 NA -0.38 -6.71 -0.34 8.32e-11 Protein biomarker; LIHC cis rs611744 0.901 rs673981 chr8:109191917 G/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs2576037 0.526 rs564113 chr18:44364389 A/T cg19077165 chr18:44547161 KATNAL2 -0.43 -6.51 -0.33 2.64e-10 Personality dimensions; LIHC cis rs6426558 0.537 rs689094 chr1:227308909 G/A cg10327440 chr1:227177885 CDC42BPA 0.46 7.08 0.36 7.98e-12 Neutrophil percentage of white cells; LIHC cis rs1639906 0.895 rs34255795 chr7:2207416 A/G cg02951883 chr7:2050386 MAD1L1 0.54 7.29 0.37 2.21e-12 Colonoscopy-negative controls vs population controls; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg05052194 chr1:2160249 SKI -0.44 -6.4 -0.33 5.16e-10 Triglycerides; LIHC cis rs67311347 1.000 rs4973878 chr3:40407565 C/T cg13409248 chr3:40428643 ENTPD3 0.4 6.64 0.34 1.23e-10 Renal cell carcinoma; LIHC cis rs2290416 0.892 rs62523607 chr8:144667432 G/A cg26536354 chr8:144654954 C8orf73 0.56 6.3 0.32 9.39e-10 Attention deficit hyperactivity disorder; LIHC cis rs507080 0.736 rs642224 chr11:118570919 G/A cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs13161895 0.713 rs76315806 chr5:179485515 C/G cg02702477 chr5:179499311 RNF130 0.9 11.96 0.54 9.23e-28 LDL cholesterol; LIHC cis rs17152411 1.000 rs7083298 chr10:126590691 T/C cg07906193 chr10:126599966 NA 0.46 7.11 0.36 6.9e-12 Height; LIHC cis rs2274273 0.837 rs7142857 chr14:55704128 C/T cg04306507 chr14:55594613 LGALS3 0.34 6.56 0.33 2.05e-10 Protein biomarker; LIHC cis rs6835098 0.962 rs4377567 chr4:174083590 C/G cg27433088 chr4:174089019 GALNT7 -0.37 -7.02 -0.36 1.16e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs17685 0.753 rs6951808 chr7:75772413 A/G cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4925386 1.000 rs4925389 chr20:60922512 G/A cg24112000 chr20:60950667 NA 0.44 6.93 0.35 2.07e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs9733 0.818 rs12403609 chr1:150676485 T/C cg17724175 chr1:150552817 MCL1 -0.38 -7.84 -0.39 5.72e-14 Tonsillectomy; LIHC cis rs1385374 0.800 rs12321679 chr12:129284791 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -5.83 -0.3 1.32e-8 Systemic lupus erythematosus; LIHC trans rs61931739 0.517 rs10844727 chr12:34017435 C/T cg26384229 chr12:38710491 ALG10B 0.48 6.76 0.34 5.96e-11 Morning vs. evening chronotype; LIHC cis rs589448 0.933 rs523398 chr12:69752775 C/T cg14784868 chr12:69753453 YEATS4 1.0 23.05 0.78 1.35e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg07092213 chr7:1199455 ZFAND2A -0.46 -7.11 -0.36 6.9e-12 Longevity;Endometriosis; LIHC trans rs801193 0.901 rs4273746 chr7:66301111 C/T cg26939375 chr7:64535504 NA -0.43 -6.25 -0.32 1.21e-9 Aortic root size; LIHC cis rs1975974 1.000 rs17052337 chr17:21710774 A/T cg18423549 chr17:21743878 NA -0.45 -5.74 -0.3 2.07e-8 Psoriasis; LIHC cis rs4803468 1.000 rs2569754 chr19:41936734 A/G cg09537434 chr19:41945824 ATP5SL -1.03 -22.1 -0.77 7.56e-68 Height; LIHC cis rs2070488 1.000 rs1002676 chr3:38444932 A/C cg24069376 chr3:38537580 EXOG -0.42 -7.71 -0.38 1.4e-13 Electrocardiographic conduction measures; LIHC cis rs1707322 1.000 rs9803784 chr1:46401907 T/C cg03146154 chr1:46216737 IPP 0.48 7.74 0.39 1.13e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6502050 0.835 rs3088177 chr17:80111724 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.41e-9 Life satisfaction; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.47 0.56 1.09e-29 Prudent dietary pattern; LIHC cis rs6570726 0.764 rs9322028 chr6:145895797 G/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.39 -0.33 5.33e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.738 rs28408407 chr4:120376030 C/G cg25214090 chr10:38739885 LOC399744 0.59 9.71 0.46 7.58e-20 Corneal astigmatism; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.53 -7.59 -0.38 3.13e-13 Lymphocyte counts; LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg03874509 chr1:107600012 PRMT6 -0.74 -11.56 -0.53 2.59e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7216064 1.000 rs7208663 chr17:65885171 T/C cg12091567 chr17:66097778 LOC651250 -0.67 -9.76 -0.47 5.24e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs11608355 0.545 rs4766604 chr12:109892179 T/C cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs7757419 1.000 rs7773901 chr6:34435195 G/A cg17518776 chr6:34434842 PACSIN1 -0.3 -6.1 -0.31 2.86e-9 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals; LIHC cis rs7845219 0.597 rs7002058 chr8:95873993 G/C cg16049864 chr8:95962084 TP53INP1 -0.53 -9.19 -0.45 3.91e-18 Type 2 diabetes; LIHC cis rs4716602 0.596 rs10258969 chr7:156157753 A/G cg16983916 chr7:156159713 NA -0.33 -6.06 -0.31 3.62e-9 Anti-saccade response; LIHC cis rs11098699 1.000 rs1031133 chr4:124195336 G/C cg09941581 chr4:124220074 SPATA5 0.3 5.72 0.3 2.29e-8 Mosquito bite size; LIHC cis rs372883 0.600 rs2832298 chr21:30743863 C/G cg24692254 chr21:30365293 RNF160 0.52 6.71 0.34 7.88e-11 Pancreatic cancer; LIHC cis rs2249694 0.960 rs7094588 chr10:135401586 A/G cg16964102 chr10:135390573 NA 0.25 5.8 0.3 1.55e-8 Obesity-related traits; LIHC cis rs12602486 1.000 rs59592125 chr17:42279265 A/G cg13607699 chr17:42295918 UBTF -0.79 -6.61 -0.34 1.47e-10 Glycated hemoglobin levels; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17928916 chr17:80041824 FASN 0.41 6.17 0.32 1.98e-9 Immature fraction of reticulocytes; LIHC cis rs2228479 0.618 rs34689166 chr16:89860697 C/T cg19635926 chr16:89946313 TCF25 0.55 6.84 0.35 3.57e-11 Skin colour saturation; LIHC cis rs679087 0.659 rs302318 chr12:29921667 T/C cg14258853 chr12:29935411 TMTC1 -0.36 -5.99 -0.31 5.4e-9 Schizophrenia; LIHC cis rs1008375 0.966 rs4698638 chr4:17632988 G/C cg15017067 chr4:17643749 FAM184B 0.34 5.84 0.3 1.23e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs116095464 0.614 rs62344292 chr5:244630 G/A cg22496380 chr5:211416 CCDC127 -1.01 -10.27 -0.49 9.22e-22 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15008879 chr10:22292810 DNAJC1 0.42 6.13 0.31 2.45e-9 Pancreatic cancer; LIHC cis rs11229555 0.645 rs7929028 chr11:58188258 C/T cg15696309 chr11:58395628 NA -0.65 -7.66 -0.38 1.95e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg04267008 chr7:1944627 MAD1L1 -0.6 -9.25 -0.45 2.42e-18 Bipolar disorder and schizophrenia; LIHC cis rs2839186 0.814 rs2839167 chr21:47661587 A/G cg11766577 chr21:47581405 C21orf56 -0.43 -6.98 -0.35 1.5e-11 Testicular germ cell tumor; LIHC cis rs1577917 1.000 rs12196411 chr6:86779762 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.27 -0.37 2.47e-12 Response to antipsychotic treatment; LIHC cis rs1023500 0.551 rs133355 chr22:42440285 G/A cg00645731 chr22:42541494 CYP2D7P1 0.4 6.37 0.33 6.24e-10 Schizophrenia; LIHC cis rs2180341 0.960 rs7745944 chr6:127709574 A/G cg24812749 chr6:127587940 RNF146 1.05 15.87 0.65 7.12e-43 Breast cancer; LIHC cis rs7474896 0.583 rs10827817 chr10:37997974 A/G cg25427524 chr10:38739819 LOC399744 -0.49 -7.2 -0.36 3.83e-12 Obesity (extreme); LIHC cis rs959260 0.858 rs2053156 chr17:73378440 G/T cg20590849 chr17:73267439 MIF4GD -0.53 -5.76 -0.3 1.85e-8 Systemic lupus erythematosus; LIHC trans rs60843830 1.000 rs3828165 chr2:220889 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.62 8.8 0.43 6.75e-17 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs727505 1.000 rs727505 chr7:124462081 C/T cg23710748 chr7:124431027 NA -0.34 -6.11 -0.31 2.68e-9 Lewy body disease; LIHC cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg27286337 chr10:134555280 INPP5A 0.95 13.5 0.59 1.39e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3749237 0.555 rs7637665 chr3:49552295 T/C cg03060546 chr3:49711283 APEH 0.59 9.74 0.47 6.2e-20 Resting heart rate; LIHC cis rs6500602 0.826 rs7205189 chr16:4460114 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.46 6.44 0.33 3.99e-10 Schizophrenia; LIHC cis rs2625529 0.824 rs4445848 chr15:72354598 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.92 -0.3 7.89e-9 Red blood cell count; LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg02290350 chr8:58132656 NA 0.52 11.05 0.51 1.82e-24 Developmental language disorder (linguistic errors); LIHC cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg27211696 chr2:191398769 TMEM194B 0.66 10.86 0.51 8.25e-24 Pulse pressure; LIHC cis rs896854 0.738 rs527234 chr8:95963798 C/G cg13393036 chr8:95962371 TP53INP1 0.38 7.95 0.39 2.74e-14 Type 2 diabetes; LIHC cis rs6089584 1.000 rs3787425 chr20:60559256 C/T cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs9549328 0.800 rs9549326 chr13:113630453 C/T cg08528486 chr13:113648767 MCF2L -0.41 -6.64 -0.34 1.22e-10 Systolic blood pressure; LIHC cis rs9868809 0.505 rs28567949 chr3:48744560 G/A cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.53e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC trans rs7674212 0.541 rs2251322 chr4:104079424 C/T cg16471864 chr4:38666270 KLF3;FLJ13197 -0.45 -6.44 -0.33 4.11e-10 Type 2 diabetes; LIHC cis rs10916814 0.632 rs10799645 chr1:20903784 T/C cg24502330 chr1:20914028 CDA -0.32 -6.92 -0.35 2.23e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs11039798 0.841 rs11500573 chr11:48713900 T/G cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs12824058 0.831 rs11608406 chr12:130805866 G/C cg24838063 chr12:130822603 PIWIL1 0.67 9.22 0.45 3.08e-18 Menopause (age at onset); LIHC cis rs7833986 0.501 rs2719261 chr8:56941982 C/G cg23139584 chr8:56987506 RPS20;SNORD54 0.73 7.64 0.38 2.18e-13 Height; LIHC cis rs9596863 0.898 rs9568914 chr13:54341107 T/C ch.13.53330881F chr13:54432880 NA 0.45 6.1 0.31 2.79e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs244293 0.729 rs2332313 chr17:53018825 T/G cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.42 -0.33 4.59e-10 Menarche (age at onset); LIHC cis rs748404 0.697 rs501884 chr15:43553982 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.47 8.03 0.4 1.64e-14 Lung cancer; LIHC cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC cis rs1552244 0.882 rs6443276 chr3:10008905 C/A cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.8e-9 Alzheimer's disease; LIHC cis rs875971 1.000 rs6958271 chr7:65979331 A/C cg11764359 chr7:65958608 NA 0.91 16.91 0.67 4.71e-47 Aortic root size; LIHC cis rs3770081 1.000 rs2289237 chr2:86266274 C/G cg01119172 chr2:86362222 SNORD94;PTCD3 -0.45 -6.27 -0.32 1.11e-9 Facial emotion recognition (sad faces); LIHC cis rs4555082 0.874 rs760270 chr14:105737785 A/G cg10792982 chr14:105748885 BRF1 0.46 6.08 0.31 3.3e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9888615 0.926 rs12433887 chr14:53322999 G/A cg00686598 chr14:53173677 PSMC6 -0.5 -6.36 -0.33 6.53e-10 Systolic blood pressure; LIHC cis rs903552 0.935 rs8041582 chr15:102005851 G/A cg19295451 chr15:102010161 PCSK6 -0.46 -6.33 -0.32 7.51e-10 Diabetic kidney disease; LIHC cis rs9858542 0.903 rs9875617 chr3:49634696 G/A cg02487422 chr3:49467188 NICN1 -0.43 -5.72 -0.3 2.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6545883 0.965 rs7421663 chr2:61753786 C/T cg14146966 chr2:61757674 XPO1 0.47 8.28 0.41 2.83e-15 Tuberculosis; LIHC trans rs1499614 0.901 rs3936 chr7:66126489 C/T cg07424592 chr7:64974309 NA 0.78 8.92 0.43 2.85e-17 Gout; LIHC cis rs1023500 0.551 rs133371 chr22:42465574 G/A cg00645731 chr22:42541494 CYP2D7P1 0.39 6.23 0.32 1.37e-9 Schizophrenia; LIHC cis rs11209002 0.545 rs2093332 chr1:67531974 G/A cg02640540 chr1:67518911 SLC35D1 0.42 5.73 0.3 2.19e-8 Crohn's disease; LIHC cis rs2404602 0.735 rs11629888 chr15:76719880 A/T cg03037974 chr15:76606532 NA -0.63 -10.8 -0.5 1.38e-23 Blood metabolite levels; LIHC cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg08392591 chr16:89556376 ANKRD11 0.5 8.04 0.4 1.52e-14 Multiple myeloma (IgH translocation); LIHC cis rs4975709 0.610 rs4975704 chr5:1859807 C/A cg14773178 chr5:1868261 NA 0.26 6.87 0.35 3.05e-11 Cardiovascular disease risk factors; LIHC cis rs9916302 0.706 rs11657153 chr17:37699729 A/G cg07936489 chr17:37558343 FBXL20 -0.84 -11.92 -0.54 1.24e-27 Glomerular filtration rate (creatinine); LIHC cis rs950169 0.580 rs17532346 chr15:85171495 A/C cg03959625 chr15:84868606 LOC388152 0.42 6.05 0.31 3.84e-9 Schizophrenia; LIHC cis rs9814567 1.000 rs11928499 chr3:134232350 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs600231 0.706 rs1111934 chr11:65329392 A/G cg17120908 chr11:65337727 SSSCA1 -0.41 -5.72 -0.3 2.36e-8 Bone mineral density; LIHC cis rs72843506 0.656 rs28567541 chr17:19955102 T/C cg12065943 chr17:19881925 AKAP10 -0.32 -5.86 -0.3 1.1e-8 Schizophrenia; LIHC cis rs7072216 0.763 rs7911036 chr10:100167015 A/T cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC trans rs7618501 0.540 rs11130241 chr3:50131459 A/T cg21659725 chr3:3221576 CRBN -0.72 -11.53 -0.53 3.33e-26 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.591 rs7027874 chr9:111717112 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.68 11.1 0.51 1.16e-24 Menarche (age at onset); LIHC cis rs7666738 0.830 rs9994346 chr4:99037986 A/G cg05340658 chr4:99064831 C4orf37 0.72 12.97 0.57 1.44e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs908922 0.676 rs4845788 chr1:152519496 T/C cg23254163 chr1:152506842 NA 0.22 5.72 0.3 2.28e-8 Hair morphology; LIHC cis rs1577917 1.000 rs1337850 chr6:86729103 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.93 -0.35 2.1e-11 Response to antipsychotic treatment; LIHC cis rs600806 0.713 rs10857786 chr1:110010110 C/G cg10127483 chr1:110009974 SYPL2 0.48 6.06 0.31 3.53e-9 Intelligence (multi-trait analysis); LIHC cis rs919433 0.680 rs6434934 chr2:198437386 C/G cg03934865 chr2:198174659 NA 0.51 7.88 0.39 4.32e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1577917 0.740 rs2758845 chr6:86334848 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.48 -9.28 -0.45 2.03e-18 Response to antipsychotic treatment; LIHC cis rs4780401 0.609 rs16958588 chr16:11819330 G/A cg01061890 chr16:11836724 TXNDC11 -0.66 -10.74 -0.5 2.25e-23 Rheumatoid arthritis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07399355 chr1:155163013 MUC1 0.41 6.65 0.34 1.16e-10 Cognitive function; LIHC cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg07636037 chr3:49044803 WDR6 0.73 11.87 0.54 1.91e-27 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs8020095 0.528 rs8004488 chr14:67667402 C/G cg03487553 chr14:67822707 ATP6V1D 0.35 6.04 0.31 3.92e-9 Depression (quantitative trait); LIHC cis rs5769765 0.773 rs9616382 chr22:50312979 C/T cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs9296092 0.538 rs115770720 chr6:33517032 A/T cg13560919 chr6:33536144 NA -0.38 -6.36 -0.33 6.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs1005277 0.579 rs2472182 chr10:38388865 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs9399135 0.967 rs11756988 chr6:135347595 A/G cg22676075 chr6:135203613 NA 0.39 6.32 0.32 8.12e-10 Red blood cell count; LIHC trans rs11098499 0.863 rs3822195 chr4:120471660 C/T cg25214090 chr10:38739885 LOC399744 0.58 9.37 0.45 1.02e-18 Corneal astigmatism; LIHC cis rs2932538 0.922 rs12401734 chr1:113071834 A/G cg22162597 chr1:113214053 CAPZA1 0.7 9.51 0.46 3.49e-19 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs1866706 0.896 rs10765999 chr11:12859917 C/T cg25843174 chr11:12811716 TEAD1 -0.31 -6.44 -0.33 4.13e-10 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.837 rs4432085 chr12:38181146 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs3806843 0.900 rs2563254 chr5:140142701 T/C cg26395211 chr5:140044315 WDR55 0.4 5.97 0.31 5.79e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7772486 0.641 rs9390374 chr6:146368175 A/T cg05347473 chr6:146136440 FBXO30 0.43 6.35 0.32 6.75e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4332037 0.539 rs56180486 chr7:2050747 C/T cg23422044 chr7:1970798 MAD1L1 -0.52 -6.14 -0.32 2.29e-9 Bipolar disorder; LIHC cis rs8084351 0.577 rs4349221 chr18:50661880 A/G cg24270629 chr18:50823537 DCC -0.44 -6.52 -0.33 2.59e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs72627509 0.638 rs7658601 chr4:57781347 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.55 -7.95 -0.39 2.77e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1075232 1.000 rs72722861 chr15:31704288 G/A cg01030201 chr15:31746330 NA -0.86 -6.64 -0.34 1.22e-10 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs7615952 0.576 rs66671308 chr3:125793526 T/G cg05084668 chr3:125655381 ALG1L -0.38 -5.92 -0.3 7.95e-9 Blood pressure (smoking interaction); LIHC trans rs8002861 0.935 rs7318147 chr13:44445153 C/G cg13511620 chr13:39611918 C13orf23;NHLRC3 0.46 6.16 0.32 2.09e-9 Leprosy; LIHC cis rs933688 1.000 rs1035476 chr5:90745976 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.81 16.37 0.66 7.03e-45 Smoking behavior; LIHC cis rs12824058 0.831 rs12297939 chr12:130811923 G/C cg24229701 chr12:130821962 PIWIL1 0.44 6.81 0.35 4.49e-11 Menopause (age at onset); LIHC cis rs8017423 0.935 rs11628952 chr14:90734953 T/C cg04374321 chr14:90722782 PSMC1 -0.77 -14.71 -0.62 2.61e-38 Mortality in heart failure; LIHC cis rs959260 1.000 rs9900002 chr17:73382018 T/A cg20590849 chr17:73267439 MIF4GD -0.54 -5.8 -0.3 1.51e-8 Systemic lupus erythematosus; LIHC cis rs9611519 0.929 rs71327107 chr22:41418229 T/G cg03806693 chr22:41940476 POLR3H -0.62 -6.8 -0.35 4.55e-11 Neuroticism; LIHC trans rs8002861 0.967 rs7994883 chr13:44478805 A/G cg17145862 chr1:211918768 LPGAT1 -0.66 -12.94 -0.57 1.89e-31 Leprosy; LIHC cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs679087 0.640 rs79708380 chr12:29909457 G/A cg14258853 chr12:29935411 TMTC1 -0.46 -6.69 -0.34 9.21e-11 Schizophrenia; LIHC cis rs3741404 0.574 rs638227 chr11:63871549 T/C cg05016508 chr11:63871570 FLRT1;MACROD1 0.42 6.68 0.34 9.66e-11 Platelet count; LIHC cis rs208520 1.000 rs72882100 chr6:66981495 G/C cg07460842 chr6:66804631 NA 0.67 7.3 0.37 2e-12 Exhaled nitric oxide output; LIHC cis rs3796352 1.000 rs35720014 chr3:52982110 A/C cg04865290 chr3:52927548 TMEM110 -0.51 -5.89 -0.3 9.01e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs55665837 0.701 rs12286408 chr11:14579376 G/A cg19336497 chr11:14380999 RRAS2 -0.36 -5.94 -0.31 6.82e-9 Vitamin D levels; LIHC trans rs11722228 0.521 rs62288520 chr4:10099674 G/A cg26043149 chr18:55253948 FECH 0.97 14.09 0.61 7.13e-36 Gout;Urate levels;Serum uric acid levels; LIHC cis rs7072216 0.763 rs8181292 chr10:100175477 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.23 -0.32 1.38e-9 Metabolite levels; LIHC cis rs644799 0.965 rs2508713 chr11:95547927 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.39 0.68 5.86e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2749592 0.550 rs12255038 chr10:37869332 T/C cg00409905 chr10:38381863 ZNF37A 0.51 8.63 0.42 2.33e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01162549 chr5:141367464 RNF14 0.41 6.45 0.33 3.76e-10 Longevity; LIHC cis rs7772486 0.840 rs11155451 chr6:146422524 A/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.29 -0.32 9.94e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1008375 1.000 rs10032326 chr4:17630717 A/T cg02297831 chr4:17616191 MED28 0.48 7.37 0.37 1.26e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1008375 1.000 rs10012335 chr4:17628630 C/G cg02297831 chr4:17616191 MED28 0.47 7.22 0.36 3.37e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11644362 1.000 rs12934970 chr16:12988077 G/C cg06890432 chr16:12997467 SHISA9 -0.4 -6.86 -0.35 3.32e-11 Positive affect;Subjective well-being; LIHC cis rs7412746 0.658 rs6669855 chr1:150861229 C/T cg18016565 chr1:150552671 MCL1 0.52 9.95 0.47 1.23e-20 Melanoma; LIHC cis rs7100689 0.577 rs2236569 chr10:82043576 G/A cg00277334 chr10:82204260 NA -0.54 -6.75 -0.34 6.5e-11 Post bronchodilator FEV1; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11339965 chr5:93954434 ANKRD32;C5orf36 0.5 6.58 0.34 1.78e-10 Lung function (FEV1/FVC); LIHC cis rs10791097 0.694 rs10894275 chr11:130756251 C/T cg22079354 chr11:130786696 SNX19 0.41 5.82 0.3 1.35e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs8072100 1.000 rs11870935 chr17:45732605 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 0.39 6.06 0.31 3.67e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs35146811 0.883 rs4134903 chr7:99711040 G/A cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.43 6.17 0.32 1.96e-9 Coronary artery disease; LIHC trans rs8073060 0.586 rs11080356 chr17:33895309 T/C cg19694781 chr19:47549865 TMEM160 1.22 13.15 0.58 3.06e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs644799 0.710 rs10765771 chr11:95521044 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.74 0.57 1.07e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2795502 0.882 rs3123754 chr10:43339011 G/A cg27426351 chr10:43362370 NA -0.46 -5.8 -0.3 1.5e-8 Blood protein levels; LIHC cis rs12477438 0.520 rs11123761 chr2:99705903 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.31 0.64 1.12e-40 Chronic sinus infection; LIHC cis rs7584330 0.704 rs60079197 chr2:238358584 A/T cg14458575 chr2:238380390 NA 0.53 7.21 0.36 3.59e-12 Prostate cancer; LIHC cis rs61712019 0.679 rs11895866 chr2:77716176 A/C cg11252801 chr2:77748917 LRRTM4 0.56 7.76 0.39 1.01e-13 Schizophrenia; LIHC cis rs6502050 0.814 rs9894554 chr17:80073423 C/G cg11859384 chr17:80120422 CCDC57 0.43 5.87 0.3 1e-8 Life satisfaction; LIHC cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg13395646 chr4:1353034 KIAA1530 -0.66 -9.42 -0.45 6.98e-19 Obesity-related traits; LIHC cis rs9296092 0.560 rs62407569 chr6:33538865 A/G cg13560919 chr6:33536144 NA -0.39 -6.62 -0.34 1.4e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs2050392 0.929 rs10826798 chr10:30700904 G/A cg25182066 chr10:30743637 MAP3K8 0.45 7.35 0.37 1.46e-12 Inflammatory bowel disease; LIHC cis rs864643 1.000 rs816520 chr3:39569713 C/T cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg10802521 chr3:52805072 NEK4 -0.44 -7.54 -0.38 4.37e-13 Bipolar disorder; LIHC cis rs2439831 0.764 rs2447193 chr15:43929733 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.28 0.45 2.02e-18 Lung cancer in ever smokers; LIHC cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg26818010 chr10:134567672 INPP5A -0.64 -8.32 -0.41 2.11e-15 Migraine; LIHC cis rs853679 0.569 rs9348798 chr6:28143011 G/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.75e-10 Depression; LIHC cis rs12701220 0.655 rs12702117 chr7:1148702 T/C cg00990874 chr7:1149470 C7orf50 -0.7 -9.97 -0.47 9.87e-21 Bronchopulmonary dysplasia; LIHC cis rs9326248 1.000 rs585849 chr11:117069061 A/G cg10130564 chr11:117069849 TAGLN 0.37 6.19 0.32 1.75e-9 Blood protein levels; LIHC cis rs6456156 0.565 rs7750209 chr6:167482895 T/G cg07741184 chr6:167504864 NA 0.27 6.24 0.32 1.32e-9 Primary biliary cholangitis; LIHC cis rs5769765 0.954 rs5769762 chr22:50264042 G/A cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs10744422 1.000 rs4759382 chr12:123347609 C/T cg25930673 chr12:123319894 HIP1R 0.85 11.06 0.51 1.6e-24 Schizophrenia; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg09455208 chr3:40491958 NA 0.39 7.92 0.39 3.48e-14 Renal cell carcinoma; LIHC cis rs9303401 0.734 rs8073316 chr17:57211381 A/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.42 -6.2 -0.32 1.63e-9 Cognitive test performance; LIHC cis rs116095464 1.000 rs28416084 chr5:217640 G/A cg22496380 chr5:211416 CCDC127 -1.15 -10.21 -0.48 1.54e-21 Breast cancer; LIHC cis rs7223966 1.000 rs2013288 chr17:61785904 C/T cg05941027 chr17:61774174 LIMD2 0.34 7.26 0.37 2.7e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs858239 0.601 rs10255228 chr7:23158863 G/T cg23682824 chr7:23144976 KLHL7 0.46 6.95 0.35 1.84e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg05896524 chr21:47604654 C21orf56 -0.49 -7.82 -0.39 6.58e-14 Testicular germ cell tumor; LIHC cis rs7927592 0.673 rs2510392 chr11:68394457 C/G cg01657329 chr11:68192670 LRP5 -0.5 -7.31 -0.37 1.9e-12 Total body bone mineral density; LIHC cis rs2067615 0.524 rs4964483 chr12:107099057 T/C cg15890332 chr12:107067104 RFX4 0.26 6.31 0.32 8.41e-10 Heart rate; LIHC cis rs9296092 0.517 rs113111213 chr6:33520790 A/G cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs919433 0.680 rs2605039 chr2:198362851 C/A cg10820045 chr2:198174542 NA 0.54 8.76 0.43 9e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1728785 0.901 rs1170444 chr16:68573287 T/C cg02972257 chr16:68554789 NA -0.56 -6.45 -0.33 3.89e-10 Ulcerative colitis; LIHC cis rs911119 1.000 rs3787499 chr20:23616807 G/A cg16589663 chr20:23618590 CST3 0.76 7.89 0.39 4.24e-14 Chronic kidney disease; LIHC cis rs7264396 0.697 rs6142416 chr20:34174092 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.5 8.23 0.41 4.08e-15 Total cholesterol levels; LIHC cis rs1419980 1.000 rs1419980 chr12:7774892 A/G cg14906510 chr12:7781169 NA -0.47 -6.76 -0.34 5.99e-11 HDL cholesterol levels; LIHC cis rs9814567 1.000 rs9854299 chr3:134206728 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.34 -0.55 3.51e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11676348 0.818 rs7425447 chr2:218980183 T/C cg00012203 chr2:219082015 ARPC2 -0.55 -7.66 -0.38 1.88e-13 Ulcerative colitis; LIHC cis rs11719291 0.833 rs34037363 chr3:48821036 C/T cg07636037 chr3:49044803 WDR6 -0.81 -8.08 -0.4 1.15e-14 Cognitive function; LIHC cis rs7615952 0.688 rs17334074 chr3:125540460 A/G cg05084668 chr3:125655381 ALG1L 0.33 6.12 0.31 2.5e-9 Blood pressure (smoking interaction); LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg04234412 chr22:24373322 LOC391322 -0.71 -10.63 -0.5 5.6e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6448317 0.906 rs4053966 chr4:24901466 A/G cg21108841 chr4:24914750 CCDC149 -0.54 -7.82 -0.39 6.42e-14 Heschl's gyrus morphology; LIHC cis rs72781680 0.716 rs2551343 chr2:24027002 C/G cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.07e-9 Lymphocyte counts; LIHC cis rs7762018 0.556 rs80250989 chr6:170105553 T/C cg19338460 chr6:170058176 WDR27 -0.84 -8.85 -0.43 4.67e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6429082 0.608 rs903348 chr1:235571343 C/T cg26050004 chr1:235667680 B3GALNT2 -0.46 -6.85 -0.35 3.49e-11 Adiposity; LIHC cis rs6674176 0.628 rs12145999 chr1:44428632 C/T cg12908607 chr1:44402522 ARTN -0.51 -8.54 -0.42 4.55e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs743757 0.878 rs750510 chr3:50546340 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.38 5.73 0.3 2.22e-8 Diastolic blood pressure; LIHC cis rs6876835 0.511 rs7729233 chr5:6597810 C/T cg04204831 chr5:6583394 LOC255167 0.42 6.46 0.33 3.67e-10 Visceral fat; LIHC cis rs748404 0.631 rs2467745 chr15:43722742 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.14 0.36 5.5e-12 Lung cancer; LIHC cis rs6545883 0.894 rs778143 chr2:61581890 A/C cg14146966 chr2:61757674 XPO1 0.42 6.98 0.35 1.53e-11 Tuberculosis; LIHC cis rs2274273 0.967 rs17832359 chr14:55615941 T/C cg01864836 chr14:55583639 NA -0.36 -6.14 -0.32 2.27e-9 Protein biomarker; LIHC cis rs9733 0.596 rs11204687 chr1:150629880 C/A cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs10847980 0.590 rs12319654 chr12:123327160 C/T cg22842854 chr12:123319900 HIP1R 0.92 10.44 0.49 2.49e-22 Adiponectin levels; LIHC cis rs10791097 0.694 rs4936123 chr11:130740967 G/A cg14779329 chr11:130786720 SNX19 0.39 5.99 0.31 5.36e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11758351 0.866 rs75091077 chr6:26207546 A/C cg06951627 chr6:26196580 NA 0.53 6.27 0.32 1.07e-9 Gout;Renal underexcretion gout; LIHC cis rs3008870 0.755 rs2755243 chr1:67482783 T/C cg02640540 chr1:67518911 SLC35D1 0.45 6.96 0.35 1.78e-11 Lymphocyte percentage of white cells; LIHC cis rs7208859 0.673 rs9903862 chr17:29206433 G/A cg13385521 chr17:29058706 SUZ12P 0.84 7.76 0.39 9.63e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs35883536 1.000 rs11547648 chr1:101106268 G/T cg14515779 chr1:101123966 NA -0.67 -13.22 -0.58 1.65e-32 Monocyte count; LIHC cis rs6693567 0.565 rs834237 chr1:150363930 A/G cg15654264 chr1:150340011 RPRD2 0.49 8.13 0.4 7.9e-15 Migraine; LIHC cis rs12477438 0.765 rs72957180 chr2:99694452 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.87 -0.51 7.74e-24 Chronic sinus infection; LIHC cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg23248424 chr5:179741104 GFPT2 0.41 5.98 0.31 5.47e-9 Height; LIHC cis rs12594515 1.000 rs8033148 chr15:45997929 G/A cg19682013 chr15:45996608 NA 0.39 6.63 0.34 1.29e-10 Waist circumference;Weight; LIHC cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg15691649 chr6:25882328 NA -0.51 -7.43 -0.37 8.62e-13 Blood metabolite levels; LIHC cis rs147538848 1 rs147538848 chr12:31466613 G/A cg15935736 chr12:31476933 FAM60A;FLJ13224 0.64 5.93 0.31 7.54e-9 Type 2 diabetes; LIHC cis rs2070488 0.804 rs1870914 chr3:38494220 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.65 10.01 0.48 7.33e-21 Electrocardiographic conduction measures; LIHC cis rs2073300 1.000 rs6114142 chr20:23461082 A/G cg12062639 chr20:23401060 NAPB 0.79 9.99 0.48 8.63e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7937890 0.732 rs7946902 chr11:14273308 C/T cg23387056 chr11:14280742 SPON1 0.45 6.24 0.32 1.31e-9 Mitochondrial DNA levels; LIHC cis rs10751667 0.643 rs11246348 chr11:939476 G/C cg10932868 chr11:921992 NA 0.39 7.35 0.37 1.44e-12 Alzheimer's disease (late onset); LIHC cis rs11671005 0.737 rs11671033 chr19:58963669 G/T cg25952890 chr19:58913133 NA 0.72 7.42 0.37 9.45e-13 Mean platelet volume; LIHC cis rs6586163 0.872 rs1926201 chr10:90746360 G/C cg03111039 chr10:90751583 FAS;ACTA2 -0.54 -7.82 -0.39 6.61e-14 Chronic lymphocytic leukemia; LIHC cis rs6598955 0.694 rs6659387 chr1:26634307 G/A cg00852783 chr1:26633632 UBXN11 0.53 8.78 0.43 7.99e-17 Obesity-related traits; LIHC cis rs2842992 0.830 rs1475123 chr6:160178007 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.46 7.48 0.37 6.46e-13 Age-related macular degeneration (geographic atrophy); LIHC cis rs2455601 1.000 rs72632952 chr11:8917976 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.47 -6.39 -0.33 5.46e-10 Schizophrenia; LIHC cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.94 0.31 6.93e-9 Calcium levels; LIHC cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg26818010 chr10:134567672 INPP5A -0.8 -9.84 -0.47 2.88e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1707322 1.000 rs11211243 chr1:46455433 G/C cg06784218 chr1:46089804 CCDC17 0.36 6.54 0.33 2.2e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs986417 0.901 rs8020084 chr14:61001495 C/T cg27398547 chr14:60952738 C14orf39 0.79 8.08 0.4 1.09e-14 Gut microbiota (bacterial taxa); LIHC trans rs208515 0.518 rs12209790 chr6:66662965 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.83 0.43 5.5e-17 Exhaled nitric oxide levels; LIHC trans rs10411161 0.702 rs7250138 chr19:52385232 G/C cg22319618 chr22:45562946 NUP50 -0.59 -8.12 -0.4 8.66e-15 Breast cancer; LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.67 0.46 1.04e-19 Height; LIHC cis rs2197308 0.703 rs10880251 chr12:37903297 G/A cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg13409248 chr3:40428643 ENTPD3 0.48 7.86 0.39 4.91e-14 Renal cell carcinoma; LIHC cis rs2573652 0.755 rs1469830 chr15:100517403 G/T cg09918751 chr15:100517450 ADAMTS17 0.97 20.45 0.74 2.68e-61 Height; LIHC cis rs12986413 0.624 rs2238601 chr19:2140374 G/T cg09261902 chr19:2140048 AP3D1 0.39 6.73 0.34 7.12e-11 Height; LIHC cis rs881375 0.967 rs876445 chr9:123677102 A/T cg14580859 chr9:123691850 NA 0.37 6.55 0.33 2.11e-10 Rheumatoid arthritis; LIHC cis rs600806 0.889 rs585545 chr1:109841662 A/T cg23091122 chr1:110024289 SYPL2 -0.46 -5.86 -0.3 1.06e-8 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg10755058 chr3:40428713 ENTPD3 0.41 6.99 0.35 1.49e-11 Renal cell carcinoma; LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg26354017 chr1:205819088 PM20D1 -0.77 -11.38 -0.52 1.13e-25 Menarche (age at onset); LIHC cis rs17253792 0.822 rs2274075 chr14:56096731 A/G cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg23978390 chr7:1156363 C7orf50 0.65 10.12 0.48 3.07e-21 Longevity;Endometriosis; LIHC cis rs1005277 0.579 rs2472174 chr10:38375382 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs3110496 0.819 rs565977 chr17:27898828 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.45 5.78 0.3 1.7e-8 Height; LIHC cis rs4746818 1.000 rs7893492 chr10:70960448 C/T cg11621586 chr10:70884670 VPS26A -0.81 -11.33 -0.52 1.72e-25 Left atrial antero-posterior diameter; LIHC cis rs4689592 0.503 rs56099074 chr4:7071259 A/G cg06697600 chr4:7070879 GRPEL1 0.65 9.55 0.46 2.54e-19 Monocyte percentage of white cells; LIHC trans rs1814175 0.645 rs10769605 chr11:49713723 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.78 0.34 5.32e-11 Height; LIHC cis rs8081395 0.741 rs2645462 chr17:57983559 T/C cg13753209 chr17:57696993 CLTC 0.38 5.82 0.3 1.33e-8 White blood cell count; LIHC cis rs2637266 0.935 rs2579774 chr10:78402253 T/C cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs8077889 0.917 rs8081646 chr17:41893360 T/C cg26893861 chr17:41843967 DUSP3 0.88 10.03 0.48 6.52e-21 Triglycerides; LIHC trans rs7618501 0.601 rs2624825 chr3:50154989 G/A cg21659725 chr3:3221576 CRBN -0.68 -10.89 -0.51 6.6e-24 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg06634786 chr22:41940651 POLR3H 0.83 8.89 0.43 3.5e-17 Vitiligo; LIHC cis rs9902453 0.874 rs3936006 chr17:28257660 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 14.18 0.61 3.16e-36 Coffee consumption (cups per day); LIHC trans rs10511404 1.000 rs6778859 chr3:120517703 G/A cg09889680 chr22:21922804 UBE2L3 -0.51 -6.51 -0.33 2.65e-10 Tumor necrosis factor alpha levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17317165 chr5:108280702 FER -0.3 -6.27 -0.32 1.06e-9 Calcium levels; LIHC cis rs7267979 0.966 rs2261794 chr20:25263062 T/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs10870270 0.957 rs3753008 chr10:133785129 A/C cg17892150 chr10:133769511 PPP2R2D -0.68 -13.16 -0.58 2.72e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs910316 0.737 rs175048 chr14:75479894 A/T cg08847533 chr14:75593920 NEK9 -0.88 -17.9 -0.7 4.87e-51 Height; LIHC cis rs2933343 0.649 rs789219 chr3:128592520 G/A cg25356066 chr3:128598488 ACAD9 0.55 7.66 0.38 1.92e-13 IgG glycosylation; LIHC cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.09e-10 Bipolar disorder; LIHC cis rs7187994 0.848 rs16974535 chr16:84783473 G/A cg07647771 chr16:84786436 USP10 -0.35 -6.91 -0.35 2.44e-11 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs8067545 0.611 rs12938355 chr17:20195217 A/G cg13482628 chr17:19912719 NA -0.41 -6.71 -0.34 7.96e-11 Schizophrenia; LIHC cis rs9303401 0.538 rs35454383 chr17:56475599 C/T cg25039879 chr17:56429692 SUPT4H1 0.86 9.52 0.46 3.2e-19 Cognitive test performance; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg18279126 chr7:2041391 MAD1L1 -0.36 -6.02 -0.31 4.51e-9 Bipolar disorder and schizophrenia; LIHC cis rs8067545 0.611 rs2042046 chr17:20018841 A/G cg13482628 chr17:19912719 NA 0.41 6.61 0.34 1.52e-10 Schizophrenia; LIHC cis rs2574704 0.781 rs28649408 chr3:11650913 A/T cg15876825 chr3:11651881 VGLL4 0.45 7.02 0.35 1.2e-11 Body mass index; LIHC cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs17473412 0.677 rs11745493 chr5:122847622 A/G cg04915494 chr16:2962968 FLYWCH1 -0.46 -6.21 -0.32 1.53e-9 Total body bone mineral density; LIHC cis rs3845702 1.000 rs262279 chr2:180869145 G/A cg01881094 chr2:180872142 CWC22 0.44 5.73 0.3 2.18e-8 Schizophrenia; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg15382696 chr6:118971807 C6orf204 0.62 6.45 0.33 3.75e-10 Diastolic blood pressure; LIHC cis rs1005277 0.579 rs1780145 chr10:38537070 A/G cg00409905 chr10:38381863 ZNF37A -0.57 -9.54 -0.46 2.77e-19 Extrinsic epigenetic age acceleration; LIHC cis rs9814567 0.964 rs9820150 chr3:134223011 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.38 -0.56 2.41e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4653767 1.000 rs10495249 chr1:226919119 A/G cg05262829 chr1:226921576 ITPKB 0.43 8.28 0.41 2.76e-15 Parkinson's disease; LIHC cis rs9898641 1 rs9898641 chr17:57571033 T/C cg02344993 chr17:57696989 CLTC 0.45 6.84 0.35 3.63e-11 Interleukin-1-beta levels; LIHC cis rs68170813 0.559 rs6949961 chr7:106850755 G/T cg02696742 chr7:106810147 HBP1 0.5 5.82 0.3 1.34e-8 Coronary artery disease; LIHC cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg19318889 chr4:1322082 MAEA 0.67 10.46 0.49 2.12e-22 Longevity; LIHC cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.48 -8.66 -0.42 1.86e-16 Prudent dietary pattern; LIHC cis rs1577917 0.727 rs2758840 chr6:86304625 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.86 -0.39 5.13e-14 Response to antipsychotic treatment; LIHC cis rs7772486 0.764 rs7762562 chr6:146158994 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.79 0.3 1.6e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs2243480 1.000 rs160642 chr7:65558373 C/T cg10756647 chr7:56101905 PSPH 1.06 13.28 0.58 9.29e-33 Diabetic kidney disease; LIHC cis rs7220401 0.515 rs8080772 chr17:28413129 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.66 -8.08 -0.4 1.13e-14 Coronary artery disease; LIHC trans rs4843747 0.671 rs72818576 chr16:88111019 C/G cg09572067 chr16:29127029 RRN3P2 0.51 8.22 0.41 4.35e-15 Menopause (age at onset); LIHC cis rs743757 1.000 rs743756 chr3:50481717 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.37 0.37 1.3e-12 Diastolic blood pressure; LIHC trans rs2832191 0.632 rs1984011 chr21:30337831 T/A cg14791747 chr16:20752902 THUMPD1 0.49 6.7 0.34 8.38e-11 Dental caries; LIHC trans rs11098499 0.662 rs13108589 chr4:120268102 G/C cg25214090 chr10:38739885 LOC399744 0.49 8.02 0.4 1.7e-14 Corneal astigmatism; LIHC cis rs2180341 0.960 rs7751865 chr6:127683040 G/A cg24812749 chr6:127587940 RNF146 1.04 15.21 0.64 3.01e-40 Breast cancer; LIHC cis rs6088590 0.813 rs1884668 chr20:33285514 A/G cg08999081 chr20:33150536 PIGU 0.61 11.18 0.52 6.06e-25 Coronary artery disease; LIHC cis rs875971 0.545 rs75840613 chr7:65841386 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.1 0.36 7.27e-12 Aortic root size; LIHC cis rs2073300 1.000 rs6114138 chr20:23457350 G/A cg12062639 chr20:23401060 NAPB 0.78 9.7 0.46 8.37e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7408868 1.000 rs4809030 chr19:15273381 A/G cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC cis rs2380220 0.808 rs2613554 chr6:95916782 C/A cg15832292 chr6:96025679 MANEA -0.62 -7.02 -0.35 1.2e-11 Behavioural disinhibition (generation interaction); LIHC trans rs11722228 0.522 rs7662229 chr4:10133014 A/T cg26043149 chr18:55253948 FECH 0.96 14.75 0.62 1.96e-38 Gout;Urate levels;Serum uric acid levels; LIHC cis rs2153535 0.601 rs1928183 chr6:8530018 A/G cg21535247 chr6:8435926 SLC35B3 0.65 8.6 0.42 2.93e-16 Motion sickness; LIHC cis rs8180040 0.800 rs11920354 chr3:47262246 C/A cg16586182 chr3:47516702 SCAP 0.49 8.87 0.43 4.11e-17 Colorectal cancer; LIHC cis rs2153535 0.580 rs9393021 chr6:8466123 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg08280861 chr8:58055591 NA 0.49 6.13 0.31 2.38e-9 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg23978390 chr7:1156363 C7orf50 0.5 7.26 0.37 2.62e-12 Longevity;Endometriosis; LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg10755058 chr3:40428713 ENTPD3 -0.41 -7.14 -0.36 5.64e-12 Renal cell carcinoma; LIHC cis rs4638749 0.677 rs7594896 chr2:108835502 C/T cg25838818 chr2:108905173 SULT1C2 -0.39 -6.79 -0.34 4.97e-11 Blood pressure; LIHC cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg09455208 chr3:40491958 NA 0.34 6.78 0.34 5.26e-11 Renal cell carcinoma; LIHC cis rs10751667 0.560 rs10902265 chr11:1003642 G/A cg06064525 chr11:970664 AP2A2 -0.44 -10.62 -0.5 5.79e-23 Alzheimer's disease (late onset); LIHC cis rs6938 0.618 rs1133323 chr15:75212225 C/T cg14664628 chr15:75095509 CSK -0.47 -5.99 -0.31 5.3300000000000004e-09 Breast cancer; LIHC cis rs1865721 0.804 rs3745084 chr18:73142510 T/G cg26385618 chr18:73139727 C18orf62 -0.31 -8.28 -0.41 2.86e-15 Intelligence; LIHC cis rs1144333 0.737 rs1144339 chr1:76280543 A/G cg22875332 chr1:76189707 ACADM -0.42 -6.78 -0.34 5.34e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs9303401 0.614 rs34058624 chr17:57118121 T/C cg25039879 chr17:56429692 SUPT4H1 0.76 8.76 0.43 9.52e-17 Cognitive test performance; LIHC cis rs897984 0.537 rs8045637 chr16:30818662 C/T cg02466173 chr16:30829666 NA -0.44 -7.47 -0.37 6.58e-13 Dementia with Lewy bodies; LIHC cis rs17125944 0.505 rs77433996 chr14:53212263 G/A cg13660082 chr14:53194042 PSMC6 -0.46 -8.01 -0.4 1.76e-14 Alzheimer's disease (late onset); LIHC cis rs116248771 0.739 rs4679831 chr3:158320988 C/T cg16708174 chr3:158430962 RARRES1 0.47 6.08 0.31 3.12e-9 diarrhoeal disease at age 2; LIHC cis rs10779751 0.770 rs6674994 chr1:11239515 T/C cg08854313 chr1:11322531 MTOR 0.85 14.35 0.61 7.24e-37 Body mass index; LIHC cis rs1580019 0.922 rs1376289 chr7:32486980 C/G cg06627557 chr7:32535165 LSM5;AVL9 -0.92 -14.92 -0.63 4.12e-39 Cognitive ability; LIHC cis rs1580019 0.537 rs7804609 chr7:32558094 A/C cg06627557 chr7:32535165 LSM5;AVL9 1.15 26.36 0.82 2.29e-84 Cognitive ability; LIHC cis rs861020 0.560 rs649275 chr1:209950681 T/C cg09163369 chr1:210001066 C1orf107 0.39 5.78 0.3 1.69e-8 Orofacial clefts; LIHC cis rs6754311 0.773 rs632632 chr2:136638216 A/G cg25344623 chr2:136566232 LCT -0.41 -8.27 -0.41 3.04e-15 Mosquito bite size; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14334965 chr14:100705150 YY1 -0.58 -6.58 -0.34 1.82e-10 Systolic blood pressure; LIHC cis rs72627509 0.638 rs78272732 chr4:57870537 T/A cg26694713 chr4:57773883 REST 0.66 8.8 0.43 6.82e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs6466055 0.739 rs6943183 chr7:104819479 T/C cg04380332 chr7:105027541 SRPK2 -0.35 -6.61 -0.34 1.47e-10 Schizophrenia; LIHC cis rs12922317 1.000 rs16958792 chr16:12075684 C/A cg09319797 chr16:12061715 TNFRSF17 0.42 7.28 0.37 2.33e-12 Schizophrenia; LIHC cis rs60871478 0.635 rs4311567 chr7:792295 T/C cg27478167 chr7:817139 HEATR2 -0.51 -6.75 -0.34 6.36e-11 Cerebrospinal P-tau181p levels; LIHC cis rs7917772 0.582 rs7907417 chr10:104370662 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.74 -0.39 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.18 -0.61 3.33e-36 Alzheimer's disease; LIHC cis rs11764590 0.694 rs7797112 chr7:2085165 T/C cg23043544 chr7:2124092 MAD1L1 -0.42 -6.98 -0.35 1.5e-11 Neuroticism; LIHC cis rs5769765 1.000 rs5770742 chr22:50270309 T/C cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs67981189 0.574 rs2010713 chr14:71368735 T/G cg15816911 chr14:71606274 NA -0.41 -6.55 -0.33 2.13e-10 Schizophrenia; LIHC cis rs1008375 0.544 rs7685265 chr4:17568510 C/T cg04450456 chr4:17643702 FAM184B 0.33 5.74 0.3 2.06e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs67460515 0.892 rs7648279 chr3:160979646 G/A cg17135325 chr3:160939158 NMD3 0.53 7.66 0.38 1.88e-13 Parkinson's disease; LIHC cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg12463550 chr7:65579703 CRCP -0.67 -7.05 -0.36 9.92e-12 Diabetic kidney disease; LIHC cis rs1707322 1.000 rs12097799 chr1:46459886 C/A cg06784218 chr1:46089804 CCDC17 0.38 6.88 0.35 2.81e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1580019 0.537 rs7804609 chr7:32558094 A/C cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.18 0.32 1.86e-9 Cognitive ability; LIHC cis rs881375 0.678 rs7031752 chr9:123663482 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.57 0.33 1.92e-10 Rheumatoid arthritis; LIHC cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg24209194 chr3:40518798 ZNF619 0.6 8.65 0.42 2.08e-16 Renal cell carcinoma; LIHC cis rs1215050 0.740 rs783916 chr4:99026264 A/C cg05340658 chr4:99064831 C4orf37 -0.42 -6.56 -0.33 2.03e-10 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.616 rs1794139 chr11:49910855 C/T cg18944383 chr4:111397179 ENPEP 0.29 7.16 0.36 4.84e-12 Height; LIHC cis rs6545883 0.929 rs1900572 chr2:61650715 T/G cg15711740 chr2:61764176 XPO1 0.41 5.77 0.3 1.76e-8 Tuberculosis; LIHC cis rs7937682 0.737 rs679032 chr11:111423286 G/T cg09085632 chr11:111637200 PPP2R1B -0.75 -9.35 -0.45 1.18e-18 Primary sclerosing cholangitis; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.72 11.99 0.54 6.75e-28 Prudent dietary pattern; LIHC cis rs7577696 0.568 rs410469 chr2:32476992 G/T cg02381751 chr2:32503542 YIPF4 -0.47 -6.61 -0.34 1.46e-10 Inflammatory biomarkers; LIHC cis rs763121 0.889 rs9610971 chr22:38910810 C/T cg14440974 chr22:39074834 NA -0.38 -5.91 -0.3 8.33e-9 Menopause (age at onset); LIHC cis rs66569888 0.789 rs17213510 chr2:106742778 T/C cg23109721 chr2:106886537 NA -0.65 -5.98 -0.31 5.59e-9 Facial morphology (factor 23); LIHC cis rs9457247 0.663 rs12526548 chr6:167431147 C/T cg23791538 chr6:167370224 RNASET2 -0.53 -8.64 -0.42 2.21e-16 Crohn's disease; LIHC cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.18 11.83 0.54 2.74e-27 Platelet count; LIHC trans rs1814175 0.817 rs1818890 chr11:49856882 T/C cg18944383 chr4:111397179 ENPEP 0.27 7.13 0.36 6.13e-12 Height; LIHC cis rs17106184 1.000 rs1278522 chr1:50895031 T/C cg07174182 chr1:51127561 FAF1 -0.55 -6.18 -0.32 1.81e-9 Type 2 diabetes; LIHC cis rs4654899 1.000 rs885363 chr1:21325360 C/A cg08539965 chr1:21396338 EIF4G3 0.34 5.91 0.3 8.14e-9 Superior frontal gyrus grey matter volume; LIHC cis rs599083 0.530 rs686921 chr11:68170833 G/T cg16797656 chr11:68205561 LRP5 -0.48 -7.47 -0.37 6.85e-13 Bone mineral density (spine); LIHC cis rs1401999 1.000 rs4148575 chr3:183702275 A/G cg01324343 chr3:183735012 ABCC5 0.76 12.82 0.57 5.22e-31 Anterior chamber depth; LIHC trans rs1814175 0.765 rs11493326 chr11:50018063 T/C cg18944383 chr4:111397179 ENPEP 0.28 7.09 0.36 7.98e-12 Height; LIHC cis rs13108904 0.539 rs13141169 chr4:1340353 C/T cg22903657 chr4:1355424 KIAA1530 -0.43 -6.23 -0.32 1.37e-9 Obesity-related traits; LIHC cis rs10751667 0.600 rs7950955 chr11:1011490 G/A cg06064525 chr11:970664 AP2A2 -0.44 -10.73 -0.5 2.49e-23 Alzheimer's disease (late onset); LIHC cis rs9611565 0.506 rs1883825 chr22:41703408 A/G cg06634786 chr22:41940651 POLR3H -0.53 -6.14 -0.32 2.23e-9 Vitiligo; LIHC cis rs12101261 0.560 rs1035144 chr14:81445121 C/T cg06600135 chr14:81408086 NA 0.43 7.72 0.39 1.26e-13 Graves' disease; LIHC trans rs637571 0.510 rs3892696 chr11:65582341 G/C cg17712092 chr4:129076599 LARP1B -0.67 -9.78 -0.47 4.34e-20 Eosinophil percentage of white cells; LIHC cis rs9905704 0.647 rs6503892 chr17:57067086 G/A cg05425664 chr17:57184151 TRIM37 -0.42 -5.83 -0.3 1.25e-8 Testicular germ cell tumor; LIHC cis rs9818758 0.607 rs35673421 chr3:49139406 G/A cg06212747 chr3:49208901 KLHDC8B -0.66 -5.81 -0.3 1.45e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1816752 0.837 rs7139748 chr13:24985669 G/A cg02811702 chr13:24901961 NA 0.24 5.83 0.3 1.3e-8 Obesity-related traits; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg00280220 chr17:61926910 NA -0.43 -6.94 -0.35 1.99e-11 Prudent dietary pattern; LIHC cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.06 12.15 0.55 1.74e-28 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16890600 chr5:98265530 NA 0.48 7.04 0.36 1.08e-11 Cognitive function; LIHC cis rs6952808 0.572 rs1860826 chr7:2112506 G/A cg20295408 chr7:1910781 MAD1L1 -0.46 -6.59 -0.34 1.64e-10 Bipolar disorder and schizophrenia; LIHC cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.51 0.33 2.68e-10 Bipolar disorder; LIHC cis rs7772486 0.641 rs2777485 chr6:146334377 G/A cg13319975 chr6:146136371 FBXO30 -0.54 -8.6 -0.42 2.88e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs10256972 0.967 rs7799110 chr7:1039065 A/G cg23978390 chr7:1156363 C7orf50 0.49 7.52 0.38 4.81e-13 Longevity;Endometriosis; LIHC cis rs6964587 0.655 rs6465351 chr7:91773213 T/C cg17063962 chr7:91808500 NA 0.68 12.24 0.55 8.15e-29 Breast cancer; LIHC cis rs1878931 0.520 rs12447807 chr16:3413896 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.97 21.25 0.75 1.83e-64 Body mass index (adult); LIHC trans rs7668874 0.731 rs7691188 chr4:116746338 G/C cg08917878 chr5:172668965 NA -0.3 -6.05 -0.31 3.89e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg22029157 chr1:209979665 IRF6 -0.48 -7.72 -0.39 1.29e-13 Cleft lip with or without cleft palate; LIHC cis rs9868809 0.505 rs13434258 chr3:48738491 T/C cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.6e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs4803468 0.967 rs4803461 chr19:41908871 G/A cg09537434 chr19:41945824 ATP5SL -1.02 -21.23 -0.75 2.11e-64 Height; LIHC cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg04025307 chr7:1156635 C7orf50 0.46 7.49 0.38 5.93e-13 Longevity;Endometriosis; LIHC cis rs875971 0.830 rs427575 chr7:65519219 A/G cg18876405 chr7:65276391 NA 0.41 7.39 0.37 1.17e-12 Aortic root size; LIHC cis rs10845606 1.000 rs10845610 chr12:12839107 G/A cg04607235 chr12:12878440 APOLD1 -0.72 -8.9 -0.43 3.21e-17 Systemic lupus erythematosus; LIHC cis rs1215050 0.740 rs783924 chr4:98969234 C/T cg05340658 chr4:99064831 C4orf37 -0.4 -6.16 -0.32 2.04e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg21747090 chr2:27597821 SNX17 -0.41 -6.02 -0.31 4.53e-9 Total body bone mineral density; LIHC cis rs853679 0.517 rs9468292 chr6:28095355 G/A cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs716804 0.740 rs11602090 chr11:10194694 A/G cg01453529 chr11:10209919 SBF2 -0.29 -5.75 -0.3 1.96e-8 Neuroticism; LIHC cis rs2439831 0.681 rs956391 chr15:43617493 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.86 -15.23 -0.64 2.34e-40 Lung cancer in ever smokers; LIHC cis rs6714710 0.603 rs2278700 chr2:98427382 T/C cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC trans rs1552244 0.572 rs7645759 chr3:10157368 C/T cg26113512 chr3:38035601 VILL -0.53 -6.09 -0.31 3e-9 Alzheimer's disease; LIHC cis rs6840360 0.967 rs7684350 chr4:152672882 T/G cg22705602 chr4:152727874 NA -0.34 -7.15 -0.36 5.15e-12 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.861 rs9903363 chr17:37499604 C/G cg03013999 chr17:37608204 MED1 -0.36 -5.99 -0.31 5.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs11577318 0.853 rs12743998 chr1:26629882 G/A cg00852783 chr1:26633632 UBXN11 0.42 6.8 0.35 4.66e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs2075371 0.829 rs11770764 chr7:134003308 T/C cg11752832 chr7:134001865 SLC35B4 0.45 5.72 0.3 2.35e-8 Mean platelet volume; LIHC cis rs3780378 1.000 rs7847294 chr9:5097281 A/C cg02405213 chr9:5042618 JAK2 -0.44 -7.37 -0.37 1.33e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs72781680 0.784 rs72798406 chr2:24180144 T/C cg08917208 chr2:24149416 ATAD2B 0.62 6.25 0.32 1.25e-9 Lymphocyte counts; LIHC cis rs4906332 1.000 rs17617935 chr14:103952886 A/T cg04998671 chr14:104000505 TRMT61A -0.46 -6.24 -0.32 1.29e-9 Coronary artery disease; LIHC cis rs2439831 1.000 rs689781 chr15:43792097 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.68 0.59 2.85e-34 Lung cancer in ever smokers; LIHC cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg18252515 chr7:66147081 NA -1.3 -16.95 -0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs4906332 1.000 rs8012623 chr14:103937086 G/A cg04998671 chr14:104000505 TRMT61A -0.45 -6.18 -0.32 1.83e-9 Coronary artery disease; LIHC cis rs6701037 0.681 rs6664840 chr1:175128726 A/G cg00321850 chr1:175162397 KIAA0040 -0.44 -7.05 -0.36 9.88e-12 Alcohol dependence; LIHC cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg02475777 chr4:1388615 CRIPAK 0.41 6.01 0.31 4.79e-9 Longevity; LIHC cis rs10242455 0.702 rs55927283 chr7:99057191 G/C cg18809830 chr7:99032528 PTCD1 -0.8 -6.15 -0.32 2.16e-9 Blood metabolite levels; LIHC cis rs908922 0.702 rs569232 chr1:152526643 A/G cg20991723 chr1:152506922 NA 0.41 6.43 0.33 4.37e-10 Hair morphology; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg01699524 chr5:7869638 MTRR;FASTKD3 -0.53 -6.69 -0.34 9.31e-11 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs929354 0.742 rs7806775 chr7:156947199 A/G cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC trans rs11098499 0.644 rs6855918 chr4:120546299 C/T cg25214090 chr10:38739885 LOC399744 0.5 8.07 0.4 1.24e-14 Corneal astigmatism; LIHC cis rs9896052 0.614 rs6501803 chr17:73450225 C/T cg25649188 chr17:73499917 CASKIN2 0.44 6.57 0.33 1.86e-10 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs12579753 0.956 rs11115038 chr12:82214660 T/G cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.48e-9 Resting heart rate; LIHC cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs9951602 0.512 rs4799246 chr18:76653417 A/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.52 0.49 1.33e-22 Obesity-related traits; LIHC cis rs787274 0.619 rs1475293 chr9:115619587 C/T cg13803584 chr9:115635662 SNX30 0.54 6.21 0.32 1.54e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs600806 0.888 rs10858084 chr1:109882250 T/A cg16275483 chr1:110013120 SYPL2 -0.5 -6.35 -0.32 6.94e-10 Intelligence (multi-trait analysis); LIHC cis rs3749237 0.555 rs7637665 chr3:49552295 T/C cg06212747 chr3:49208901 KLHDC8B 0.44 5.81 0.3 1.44e-8 Resting heart rate; LIHC cis rs611744 0.870 rs638905 chr8:109203406 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs74233809 1.000 rs75970938 chr10:104793648 T/C cg03493300 chr10:104813866 CNNM2 0.47 6.17 0.32 1.97e-9 Birth weight; LIHC cis rs8177179 0.967 rs9820225 chr3:133449189 A/G cg24879335 chr3:133465180 TF 0.48 11.13 0.52 9.45e-25 Iron status biomarkers (transferrin levels); LIHC trans rs1005277 0.522 rs11011343 chr10:38002698 A/G cg23533926 chr12:111358616 MYL2 -0.32 -6.33 -0.32 7.86e-10 Extrinsic epigenetic age acceleration; LIHC cis rs12477438 0.520 rs2632276 chr2:99779655 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.96 0.6 2.2e-35 Chronic sinus infection; LIHC cis rs6750047 0.719 rs1583171 chr2:38270107 G/A cg07380506 chr2:38303506 CYP1B1 0.52 6.19 0.32 1.77e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs9733 0.536 rs10888385 chr1:150574302 T/C cg13175981 chr1:150552382 MCL1 0.63 9.72 0.47 7.21e-20 Tonsillectomy; LIHC cis rs7828089 0.542 rs7332050 chr8:22265294 G/T cg12081754 chr8:22256438 SLC39A14 0.52 7.86 0.39 5.12e-14 Verbal declarative memory; LIHC cis rs4595586 0.525 rs35046524 chr12:39414535 A/G cg26384229 chr12:38710491 ALG10B 0.51 6.05 0.31 3.8e-9 Morning vs. evening chronotype; LIHC trans rs6598955 0.585 rs11577098 chr1:26602525 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs9596863 1.000 rs9596866 chr13:54459385 A/T ch.13.53330881F chr13:54432880 NA 0.46 6.13 0.31 2.48e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs11098499 0.818 rs12498599 chr4:120468503 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.52 0.46 3.25e-19 Corneal astigmatism; LIHC cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.93 0.31 7.56e-9 Schizophrenia; LIHC trans rs3783890 1.000 rs12896142 chr14:93783443 T/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.32 0.32 8.12e-10 Body mass index; LIHC cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.35 -0.61 7.13e-37 Alzheimer's disease; LIHC cis rs67478160 0.634 rs2368559 chr14:104230535 C/T cg01849466 chr14:104193079 ZFYVE21 -0.52 -9.11 -0.44 7.27e-18 Schizophrenia; LIHC cis rs9902453 0.900 rs9910970 chr17:28478329 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.92 0.47 1.54e-20 Coffee consumption (cups per day); LIHC cis rs36051895 0.558 rs7038687 chr9:5134065 C/T cg02405213 chr9:5042618 JAK2 0.66 11.41 0.53 9.11e-26 Pediatric autoimmune diseases; LIHC cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg12751644 chr20:60527061 NA -0.36 -5.94 -0.31 6.96e-9 Body mass index; LIHC cis rs1577917 0.958 rs11755864 chr6:86691791 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.36 -5.96 -0.31 6.32e-9 Response to antipsychotic treatment; LIHC cis rs2637266 0.935 rs6480822 chr10:78354092 A/C cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.45e-10 Pulmonary function; LIHC cis rs950169 0.544 rs12913702 chr15:85153184 G/A cg17507749 chr15:85114479 UBE2QP1 0.69 7.81 0.39 6.89e-14 Schizophrenia; LIHC cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg12310025 chr6:25882481 NA -0.61 -7.55 -0.38 3.91e-13 Intelligence (multi-trait analysis); LIHC cis rs62103177 0.525 rs1835410 chr18:77702025 T/C cg20368463 chr18:77673604 PQLC1 -0.5 -6.01 -0.31 4.8e-9 Opioid sensitivity; LIHC cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg24531977 chr5:56204891 C5orf35 -0.66 -9.41 -0.45 7.35e-19 Initial pursuit acceleration; LIHC cis rs7789940 0.904 rs6948661 chr7:75961647 T/C cg10167463 chr7:75959203 YWHAG -0.45 -7.14 -0.36 5.57e-12 Multiple sclerosis; LIHC cis rs8017423 0.935 rs11621820 chr14:90727154 C/T cg04374321 chr14:90722782 PSMC1 0.78 15.47 0.64 2.74e-41 Mortality in heart failure; LIHC cis rs34779708 0.931 rs6481935 chr10:35342959 C/T cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.41e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -5.73 -0.3 2.17e-8 Diastolic blood pressure; LIHC cis rs739401 0.611 rs7130841 chr11:3043658 A/G cg25174290 chr11:3078921 CARS 0.63 9.65 0.46 1.16e-19 Longevity; LIHC cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg05368731 chr17:41323189 NBR1 0.72 12.27 0.55 6.2e-29 Menopause (age at onset); LIHC cis rs7264396 0.790 rs6060519 chr20:34217383 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -9.88 -0.47 2.07e-20 Total cholesterol levels; LIHC cis rs2412488 0.925 rs1600795 chr4:54221952 T/G cg22241045 chr4:54363911 LNX1 -0.43 -6.69 -0.34 9.27e-11 DNA methylation (variation); LIHC cis rs9616064 0.531 rs66909472 chr22:47050210 G/A cg05621596 chr22:47072043 GRAMD4 -0.7 -10.8 -0.5 1.39e-23 Urate levels in obese individuals; LIHC cis rs4728302 0.869 rs6955707 chr7:133612188 G/A cg10665199 chr7:133106180 EXOC4 0.39 6.72 0.34 7.82e-11 Intelligence;Intelligence (multi-trait analysis); LIHC trans rs208520 0.690 rs12198745 chr6:66722598 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.75 8.66 0.42 1.83e-16 Exhaled nitric oxide output; LIHC cis rs2204008 0.837 rs11180482 chr12:38235950 G/A cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC cis rs9814567 1.000 rs1138273 chr3:134261437 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7312933 1.000 rs7312933 chr12:42503467 C/T cg17420585 chr12:42539391 GXYLT1 0.38 6.32 0.32 8.04e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs9747201 0.862 rs57596657 chr17:80147978 C/T cg07393940 chr7:158741817 NA 0.56 6.73 0.34 7.12e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8009147 1 rs8009147 chr14:104264662 A/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.53 0.56 6.97e-30 Autism spectrum disorder or schizophrenia; LIHC cis rs2795502 1.000 rs2795496 chr10:43337842 G/A cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.39e-8 Blood protein levels; LIHC cis rs11690935 0.959 rs67204065 chr2:172672624 G/A cg13550731 chr2:172543902 DYNC1I2 -0.87 -16.01 -0.65 1.9e-43 Schizophrenia; LIHC cis rs5753618 0.561 rs715510 chr22:31690528 T/A cg07713946 chr22:31675144 LIMK2 -0.43 -7.8 -0.39 7.68e-14 Colorectal cancer; LIHC cis rs896854 0.738 rs527234 chr8:95963798 C/G cg23172400 chr8:95962367 TP53INP1 0.38 7.7 0.38 1.45e-13 Type 2 diabetes; LIHC cis rs2842992 0.915 rs2758335 chr6:160111011 G/A cg11366901 chr6:160182831 ACAT2 0.93 15.25 0.64 2.01e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs1008375 0.932 rs13127157 chr4:17618049 A/G cg16339924 chr4:17578868 LAP3 -0.54 -7.05 -0.36 9.96e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6545883 0.895 rs2256617 chr2:61679924 A/G cg14146966 chr2:61757674 XPO1 0.48 8.4 0.41 1.21e-15 Tuberculosis; LIHC cis rs7617773 0.780 rs35297486 chr3:48378147 T/A cg11946769 chr3:48343235 NME6 0.91 11.51 0.53 3.89e-26 Coronary artery disease; LIHC cis rs1639906 0.708 rs3779013 chr7:2210844 A/G cg02951883 chr7:2050386 MAD1L1 -0.55 -7.19 -0.36 4.17e-12 Colonoscopy-negative controls vs population controls; LIHC trans rs983392 0.680 rs56357056 chr11:59986817 A/G cg17275991 chr19:58003312 ZNF419 0.44 6.23 0.32 1.4e-9 Alzheimer's disease (late onset); LIHC cis rs12586317 0.620 rs8020370 chr14:35581432 G/A cg05294307 chr14:35346193 BAZ1A -0.46 -6.83 -0.35 4e-11 Psoriasis; LIHC cis rs12986413 0.935 rs36065733 chr19:2163771 T/G cg09261902 chr19:2140048 AP3D1 0.37 6.36 0.33 6.56e-10 Height; LIHC cis rs7772486 0.719 rs702307 chr6:145993454 C/G cg05347473 chr6:146136440 FBXO30 -0.36 -5.72 -0.3 2.39e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.929 rs2593635 chr2:61634706 A/C cg14146966 chr2:61757674 XPO1 -0.43 -7.31 -0.37 1.95e-12 Tuberculosis; LIHC cis rs710216 0.536 rs710222 chr1:43413653 A/G cg07803811 chr1:43423981 SLC2A1 0.39 5.87 0.3 1.04e-8 Red cell distribution width; LIHC cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg12310025 chr6:25882481 NA -0.6 -7.58 -0.38 3.21e-13 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.695 rs11057797 chr12:122860732 G/A cg23029597 chr12:123009494 RSRC2 0.51 7.32 0.37 1.76e-12 Body mass index; LIHC cis rs1878931 0.535 rs7188903 chr16:3412861 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.68 8.96 0.44 2.22e-17 Body mass index (adult); LIHC cis rs8180040 0.966 rs12632132 chr3:47477019 C/T cg27129171 chr3:47204927 SETD2 0.57 9.64 0.46 1.32e-19 Colorectal cancer; LIHC cis rs7582180 0.764 rs1946799 chr2:100921136 C/A cg14675211 chr2:100938903 LONRF2 0.53 8.01 0.4 1.82e-14 Intelligence (multi-trait analysis); LIHC cis rs1046896 0.553 rs8073413 chr17:80836005 G/A cg02711726 chr17:80685570 FN3KRP -0.44 -8.16 -0.4 6.4e-15 Glycated hemoglobin levels; LIHC cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg11987759 chr7:65425863 GUSB 0.39 6.21 0.32 1.56e-9 Aortic root size; LIHC cis rs7523273 0.565 rs2488248 chr1:207899682 C/T cg22525895 chr1:207977042 MIR29B2 -0.54 -8.24 -0.41 3.76e-15 Schizophrenia; LIHC cis rs3736594 0.513 rs6751087 chr2:27778016 T/C cg27432699 chr2:27873401 GPN1 0.46 6.82 0.35 4.26e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs35883536 0.669 rs1932352 chr1:101161251 G/A cg14515779 chr1:101123966 NA 0.56 7.93 0.39 3.15e-14 Monocyte count; LIHC cis rs9303401 0.573 rs34717648 chr17:56886624 T/A cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.3 0.58 7.79e-33 Cognitive test performance; LIHC cis rs8017423 0.967 rs2277515 chr14:90723000 A/G cg14092571 chr14:90743983 NA -0.38 -6.03 -0.31 4.15e-9 Mortality in heart failure; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg00280220 chr17:61926910 NA 0.42 6.89 0.35 2.73e-11 Prudent dietary pattern; LIHC cis rs12079745 0.793 rs10800430 chr1:169276782 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 1.94e-11 QT interval; LIHC cis rs12701220 0.522 rs868833 chr7:1054973 C/G cg00990874 chr7:1149470 C7orf50 -0.54 -8.08 -0.4 1.11e-14 Bronchopulmonary dysplasia; LIHC cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg11062466 chr8:58055876 NA 0.5 6.9 0.35 2.56e-11 Developmental language disorder (linguistic errors); LIHC cis rs7312933 0.703 rs12371615 chr12:42563989 C/G cg17420585 chr12:42539391 GXYLT1 -0.37 -5.86 -0.3 1.07e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6933660 0.720 rs6914656 chr6:151753421 C/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 7.5 0.38 5.41e-13 Menarche (age at onset); LIHC cis rs1461503 0.966 rs7110154 chr11:122843300 A/G cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs950169 0.922 rs11639244 chr15:84832650 G/A cg17507749 chr15:85114479 UBE2QP1 0.73 8.8 0.43 6.71e-17 Schizophrenia; LIHC cis rs6951245 0.638 rs4720486 chr7:1146764 G/A cg22907277 chr7:1156413 C7orf50 0.84 8.01 0.4 1.88e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg04546413 chr19:29218101 NA 0.57 10.01 0.48 7.23e-21 Methadone dose in opioid dependence; LIHC cis rs17253792 0.749 rs74979160 chr14:56097568 G/A cg01858014 chr14:56050164 KTN1 -0.72 -6.88 -0.35 2.92e-11 Putamen volume; LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg08229694 chr2:86422197 IMMT 0.42 6.05 0.31 3.8e-9 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs7772486 0.686 rs702305 chr6:145973840 A/G cg13319975 chr6:146136371 FBXO30 0.35 5.72 0.3 2.35e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs250677 0.524 rs250665 chr5:148454394 A/C cg18129178 chr5:148520854 ABLIM3 -0.37 -6.16 -0.32 2.09e-9 Breast cancer; LIHC cis rs6088590 0.965 rs6058108 chr20:33288655 A/G cg08999081 chr20:33150536 PIGU 0.37 5.71 0.3 2.42e-8 Coronary artery disease; LIHC cis rs7551222 0.752 rs10900599 chr1:204541943 T/C cg20240347 chr1:204465584 NA -0.33 -6.99 -0.35 1.44e-11 Schizophrenia; LIHC trans rs9929218 1.000 rs2113201 chr16:68815000 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.4 -0.41 1.22e-15 Colorectal cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03793131 chr1:43833547 ELOVL1 0.49 6.73 0.34 7.21e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg23205692 chr1:25664452 TMEM50A -0.39 -6.16 -0.32 1.99e-9 Plateletcrit;Mean corpuscular volume; LIHC cis rs11792861 0.890 rs2900481 chr9:111831825 G/A cg13535736 chr9:111863775 C9orf5 -0.4 -6.0 -0.31 4.89e-9 Menarche (age at onset); LIHC cis rs1878931 0.501 rs17136359 chr16:3420814 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.68 -10.09 -0.48 3.99e-21 Body mass index (adult); LIHC cis rs10463316 0.779 rs6896444 chr5:150777357 T/G cg03212797 chr5:150827313 SLC36A1 -0.41 -6.2 -0.32 1.59e-9 Metabolite levels (Pyroglutamine); LIHC trans rs2727020 0.823 rs7102374 chr11:49261795 G/A cg18944383 chr4:111397179 ENPEP -0.28 -6.52 -0.33 2.55e-10 Coronary artery disease; LIHC cis rs826838 1.000 rs1684416 chr12:39130301 G/A cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.63 -0.42 2.35e-16 Lymphocyte counts; LIHC cis rs11212260 0.512 rs76580404 chr11:107191013 T/C cg25435332 chr11:107328525 CWF19L2 0.75 6.87 0.35 3e-11 IgG glycosylation; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg12419862 chr22:24373484 LOC391322 -0.72 -10.94 -0.51 4.23e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs875971 0.660 rs79009421 chr7:66068509 G/C cg00343986 chr7:65444356 GUSB -0.39 -5.81 -0.3 1.45e-8 Aortic root size; LIHC cis rs892961 0.932 rs11655686 chr17:75419535 G/A cg05865280 chr17:75406074 SEPT9 0.62 11.27 0.52 2.89e-25 Airflow obstruction; LIHC cis rs11098699 0.784 rs11098701 chr4:124216461 C/G cg09941581 chr4:124220074 SPATA5 0.33 6.66 0.34 1.1e-10 Mosquito bite size; LIHC trans rs4843747 0.636 rs11117358 chr16:88105053 T/A cg26811252 chr16:29126840 RRN3P2 0.42 6.88 0.35 2.89e-11 Menopause (age at onset); LIHC trans rs668210 0.793 rs677350 chr11:65761967 G/A cg17712092 chr4:129076599 LARP1B 0.56 6.1 0.31 2.84e-9 Cerebrospinal fluid biomarker levels; LIHC trans rs1814175 0.529 rs1988417 chr11:49932430 A/G cg15704280 chr7:45808275 SEPT13 -0.86 -13.42 -0.59 2.77e-33 Height; LIHC cis rs7647973 1.000 rs13096474 chr3:49443081 C/T cg07636037 chr3:49044803 WDR6 -0.52 -6.48 -0.33 3.21e-10 Menarche (age at onset); LIHC cis rs6867032 0.958 rs4975795 chr5:2015390 G/A cg26168224 chr5:2018326 NA 0.3 7.49 0.38 5.79e-13 Gut microbiome composition (winter); LIHC cis rs733592 0.524 rs10875727 chr12:48426143 T/C cg21466736 chr12:48725269 NA 0.33 5.76 0.3 1.9e-8 Plateletcrit; LIHC cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6964587 1.000 rs2301559 chr7:91746727 T/C cg17063962 chr7:91808500 NA 1.02 19.7 0.73 2.9e-58 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13798302 chr4:100870323 LOC256880;H2AFZ 0.43 6.48 0.33 3.11e-10 Cognitive function; LIHC cis rs3749237 0.595 rs1050088 chr3:49570882 C/T cg03060546 chr3:49711283 APEH -0.63 -10.38 -0.49 3.9e-22 Resting heart rate; LIHC cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg05025164 chr4:1340916 KIAA1530 -0.4 -6.09 -0.31 2.99e-9 Obesity-related traits; LIHC cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg18404041 chr3:52824283 ITIH1 -0.48 -7.65 -0.38 2.11e-13 Electroencephalogram traits; LIHC cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.68 0.34 9.43e-11 Bipolar disorder; LIHC cis rs7937682 0.640 rs587010 chr11:111425658 C/A cg09085632 chr11:111637200 PPP2R1B -0.75 -9.35 -0.45 1.18e-18 Primary sclerosing cholangitis; LIHC cis rs921968 0.541 rs72965126 chr2:219330189 C/T cg02985541 chr2:219472218 PLCD4 -0.44 -7.11 -0.36 6.69e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs4742903 0.868 rs4743684 chr9:106852385 A/C cg14250997 chr9:106856677 SMC2 0.43 7.46 0.37 7.24e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg26939375 chr7:64535504 NA 0.47 7.15 0.36 5.33e-12 Calcium levels; LIHC cis rs6459804 0.935 rs72505543 chr7:157508867 G/A cg05731713 chr7:157510257 PTPRN2 0.24 6.45 0.33 3.84e-10 Bipolar disorder and schizophrenia; LIHC cis rs1775715 0.870 rs11008700 chr10:32236937 A/G cg14930904 chr10:32216787 ARHGAP12 0.39 6.99 0.35 1.43e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs7959452 0.640 rs4761233 chr12:69722880 T/C cg14784868 chr12:69753453 YEATS4 0.88 16.85 0.67 8.59e-47 Blood protein levels; LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs763121 0.889 rs6001209 chr22:39121252 C/T cg14440974 chr22:39074834 NA 0.41 6.46 0.33 3.56e-10 Menopause (age at onset); LIHC cis rs6951245 1.000 rs884977 chr7:1066410 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.66 5.85 0.3 1.12e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7520050 0.966 rs10890354 chr1:46305347 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs17376456 1.000 rs6867042 chr5:93555761 C/T cg25358565 chr5:93447407 FAM172A 1.1 9.99 0.48 8.93e-21 Diabetic retinopathy; LIHC trans rs4927850 0.957 rs4927851 chr3:195751853 A/G cg21051086 chr3:73046214 PPP4R2 -0.38 -6.17 -0.32 1.95e-9 Pancreatic cancer; LIHC cis rs4819052 0.788 rs2236449 chr21:46702506 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.64 9.07 0.44 9.8e-18 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11229555 0.645 rs34794607 chr11:58188401 A/T cg15696309 chr11:58395628 NA -0.65 -7.67 -0.38 1.76e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs875971 0.660 rs1860468 chr7:66107252 T/C cg26939375 chr7:64535504 NA -0.4 -6.49 -0.33 2.95e-10 Aortic root size; LIHC cis rs1005277 0.579 rs1780121 chr10:38529437 C/A cg03665457 chr10:38645376 HSD17B7P2 -0.46 -6.6 -0.34 1.54e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7945705 0.967 rs1569408 chr11:8909732 G/A cg12365402 chr11:9010492 NRIP3 0.3 7.72 0.39 1.29e-13 Hemoglobin concentration; LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg07157834 chr1:205819609 PM20D1 0.79 12.26 0.55 6.93e-29 Menarche (age at onset); LIHC cis rs4727027 0.933 rs917123 chr7:148848358 G/A cg23583168 chr7:148888333 NA -0.73 -10.54 -0.5 1.14e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2635047 0.967 rs2576030 chr18:44659166 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.5 6.81 0.35 4.41e-11 Educational attainment; LIHC cis rs10464366 0.560 rs11763728 chr7:39145862 C/T cg20302533 chr7:39170763 POU6F2 0.32 6.33 0.32 7.48e-10 IgG glycosylation; LIHC cis rs16958440 1.000 rs2289132 chr18:44602292 G/A cg17192377 chr18:44677553 HDHD2 0.59 6.52 0.33 2.56e-10 Sitting height ratio; LIHC cis rs77633900 0.881 rs1875883 chr15:76638231 C/T cg21673338 chr15:77095150 SCAPER -0.53 -5.89 -0.3 9.09e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs826838 1.000 rs11183747 chr12:38822595 A/G cg26384229 chr12:38710491 ALG10B -1.06 -14.27 -0.61 1.48e-36 Heart rate; LIHC cis rs918629 0.798 rs3777162 chr5:95293412 G/A cg10483112 chr5:95245456 ELL2 -0.35 -6.05 -0.31 3.91e-9 IgG glycosylation; LIHC cis rs3736485 0.934 rs12442803 chr15:51898754 C/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.07 -0.31 3.31e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4684776 0.676 rs2067472 chr3:11299190 G/C cg00170343 chr3:11313890 ATG7 -0.48 -6.47 -0.33 3.31e-10 Small vessel stroke; LIHC cis rs4555082 0.874 rs2816626 chr14:105735425 G/A cg10792982 chr14:105748885 BRF1 0.45 6.05 0.31 3.8e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs8060686 0.641 rs78537727 chr16:68120606 A/G cg05110241 chr16:68378359 PRMT7 -0.6 -6.96 -0.35 1.74e-11 HDL cholesterol;Metabolic syndrome; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg14875682 chr5:52083620 ITGA1;PELO -0.44 -6.42 -0.33 4.43e-10 Triglycerides; LIHC cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg08888203 chr3:10149979 C3orf24 0.57 6.84 0.35 3.72e-11 Alzheimer's disease; LIHC cis rs6840360 1.000 rs6823421 chr4:152604719 T/C cg22705602 chr4:152727874 NA -0.31 -6.45 -0.33 3.82e-10 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.766 rs2739511 chr1:231526490 G/C cg06096015 chr1:231504339 EGLN1 0.51 9.46 0.46 5.23e-19 Hemoglobin concentration; LIHC cis rs34779708 0.931 rs72789690 chr10:35382817 T/C cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 1.000 rs2036264 chr7:65799904 G/A cg11764359 chr7:65958608 NA -0.92 -17.1 -0.68 8.54e-48 Aortic root size; LIHC cis rs7107174 1.000 rs2511180 chr11:77937255 A/G cg02023728 chr11:77925099 USP35 0.47 8.88 0.43 3.75e-17 Testicular germ cell tumor; LIHC cis rs881375 0.715 rs10985073 chr9:123643855 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.76 0.34 5.91e-11 Rheumatoid arthritis; LIHC cis rs7635838 0.785 rs904475 chr3:11535417 G/A cg00170343 chr3:11313890 ATG7 0.39 6.07 0.31 3.33e-9 HDL cholesterol; LIHC cis rs9467773 1.000 rs1078679 chr6:26568741 C/T cg11502198 chr6:26597334 ABT1 0.48 6.93 0.35 2.07e-11 Intelligence (multi-trait analysis); LIHC cis rs12594515 1.000 rs12185095 chr15:45994635 G/T cg19682013 chr15:45996608 NA 0.38 6.52 0.33 2.53e-10 Waist circumference;Weight; LIHC cis rs3096299 0.967 rs2965932 chr16:89477051 C/T cg06640241 chr16:89574553 SPG7 -0.62 -9.83 -0.47 3.06e-20 Multiple myeloma (IgH translocation); LIHC cis rs5758511 0.514 rs5751240 chr22:42595258 G/C cg20195005 chr22:42527684 CYP2D6 0.31 5.79 0.3 1.57e-8 Birth weight; LIHC trans rs7395662 0.591 rs7483212 chr11:48607182 T/A cg15704280 chr7:45808275 SEPT13 -0.47 -7.01 -0.35 1.29e-11 HDL cholesterol; LIHC cis rs6582630 0.537 rs3942440 chr12:38459672 A/G cg13010199 chr12:38710504 ALG10B 0.43 5.72 0.3 2.27e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs2153535 0.580 rs9406164 chr6:8470048 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs2710642 0.849 rs4671450 chr2:62981869 C/A cg17519650 chr2:63277830 OTX1 -0.54 -8.38 -0.41 1.44e-15 LDL cholesterol levels;LDL cholesterol; LIHC cis rs9318086 0.712 rs3794339 chr13:24434065 A/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.57 11.25 0.52 3.54e-25 Myopia (pathological); LIHC cis rs7116495 1.000 rs596629 chr11:71562576 T/C cg26138937 chr11:71823887 C11orf51 0.67 6.52 0.33 2.6e-10 Severe influenza A (H1N1) infection; LIHC trans rs7618501 0.635 rs7635002 chr3:49989155 T/G cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.17 0.44 4.38e-18 Intelligence (multi-trait analysis); LIHC cis rs7520050 1.000 rs7540699 chr1:46338585 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7843479 0.965 rs733544 chr8:21835628 A/G cg17168535 chr8:21777572 XPO7 0.42 6.68 0.34 9.42e-11 Mean corpuscular volume; LIHC cis rs7224685 0.569 rs12947597 chr17:3999199 A/G cg11204139 chr17:3907470 NA -0.47 -6.16 -0.32 2.05e-9 Type 2 diabetes; LIHC trans rs561341 0.882 rs2428337 chr17:30299467 C/T cg20587970 chr11:113659929 NA -1.38 -11.69 -0.53 8.8e-27 Hip circumference adjusted for BMI; LIHC cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg24004478 chr7:855632 UNC84A 0.49 8.06 0.4 1.3e-14 Perceived unattractiveness to mosquitoes; LIHC cis rs12220238 0.730 rs10740421 chr10:75941002 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.7 6.67 0.34 1.01e-10 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22975147 chr17:8021903 ALOXE3 0.39 6.59 0.34 1.7e-10 Cognitive function; LIHC cis rs2933343 0.700 rs876754 chr3:128627753 T/C cg25356066 chr3:128598488 ACAD9 0.53 7.39 0.37 1.14e-12 IgG glycosylation; LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg14709524 chr16:89940631 TCF25 0.59 7.53 0.38 4.51e-13 Skin colour saturation; LIHC cis rs7937682 0.710 rs674230 chr11:111437887 A/G cg09085632 chr11:111637200 PPP2R1B -0.92 -10.95 -0.51 4.06e-24 Primary sclerosing cholangitis; LIHC cis rs559928 0.556 rs734762 chr11:63912189 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 7.46 0.37 7.18e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7267979 0.899 rs442834 chr20:25458096 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.45 6.77 0.34 5.56e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7408868 1.000 rs7247835 chr19:15262844 A/G cg02272795 chr19:15279244 NOTCH3 -0.32 -5.87 -0.3 1.02e-8 Pulse pressure; LIHC cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg12373951 chr3:133503437 NA -0.54 -9.29 -0.45 1.87e-18 Iron status biomarkers; LIHC cis rs7100689 0.646 rs4265545 chr10:82119271 G/T cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs798554 1.000 rs798550 chr7:2760609 A/G cg13628971 chr7:2884303 GNA12 0.51 7.44 0.37 8.48e-13 Height; LIHC cis rs10088262 0.629 rs7827665 chr8:124804190 G/A cg02993010 chr8:124780839 FAM91A1 -0.49 -6.32 -0.32 8.13e-10 Pancreatic cancer; LIHC cis rs11674184 0.659 rs11679605 chr2:11722468 G/A cg07314298 chr2:11723111 GREB1 -0.53 -8.33 -0.41 1.96e-15 Endometriosis; LIHC cis rs1577917 0.771 rs9362233 chr6:86358247 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -8.13 -0.4 7.86e-15 Response to antipsychotic treatment; LIHC trans rs11098499 0.863 rs2291185 chr4:120434833 C/A cg25214090 chr10:38739885 LOC399744 0.6 9.69 0.46 9.01e-20 Corneal astigmatism; LIHC cis rs9916302 0.851 rs4794810 chr17:37603774 T/C cg07936489 chr17:37558343 FBXL20 -0.84 -13.62 -0.59 4.61e-34 Glomerular filtration rate (creatinine); LIHC cis rs9818758 0.607 rs9855123 chr3:49229457 C/T cg07636037 chr3:49044803 WDR6 -0.82 -8.43 -0.41 1e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs12295403 1.000 rs12789252 chr11:18690389 C/T cg09887367 chr11:18690185 NA -0.4 -6.82 -0.35 4.09e-11 Ovarian reserve; LIHC cis rs1707322 1.000 rs9793167 chr1:46446800 G/A cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10779751 1.000 rs1135172 chr1:11301714 C/T cg08854313 chr1:11322531 MTOR -0.75 -11.68 -0.53 9.53e-27 Body mass index; LIHC cis rs10419226 0.625 rs12980154 chr19:18770119 C/T cg14292368 chr19:18793705 CRTC1 -0.54 -8.99 -0.44 1.68e-17 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs2073300 1.000 rs6132626 chr20:23444672 T/C cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1055129 0.655 rs3744006 chr17:73838816 G/A cg08125733 chr17:73851984 WBP2 0.51 8.24 0.41 3.84e-15 White matter hyperintensity burden; LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs11030122 0.702 rs10767713 chr11:3950157 T/C cg18678763 chr11:4115507 RRM1 -0.55 -8.27 -0.41 3.11e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs2760061 0.598 rs605410 chr1:228116281 A/G cg02753203 chr1:228287806 NA -0.49 -7.74 -0.39 1.1e-13 Diastolic blood pressure; LIHC trans rs11165623 0.602 rs4127309 chr1:97006892 T/C cg10631902 chr5:14652156 NA -0.26 -6.47 -0.33 3.37e-10 Hip circumference;Waist circumference; LIHC cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg21724239 chr8:58056113 NA 0.48 6.36 0.33 6.43e-10 Developmental language disorder (linguistic errors); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg04585227 chr7:158671570 WDR60 0.42 6.17 0.32 1.89e-9 Alopecia areata; LIHC cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg02290350 chr8:58132656 NA 0.45 8.65 0.42 2.09e-16 Developmental language disorder (linguistic errors); LIHC cis rs7116495 0.737 rs7101553 chr11:71753903 C/T cg10381502 chr11:71823885 C11orf51 -1.08 -9.2 -0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs826838 0.616 rs10880738 chr12:38617762 C/T cg26384229 chr12:38710491 ALG10B -0.51 -7.08 -0.36 8.34e-12 Heart rate; LIHC cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg12311346 chr5:56204834 C5orf35 -0.55 -7.2 -0.36 3.93e-12 Type 2 diabetes; LIHC cis rs4144743 0.877 rs7218773 chr17:45324211 C/T cg18085866 chr17:45331354 ITGB3 -0.59 -8.53 -0.42 4.87e-16 Body mass index; LIHC cis rs2421770 0.530 rs4755396 chr11:35370624 G/A cg13971030 chr11:35366721 SLC1A2 -0.45 -7.6 -0.38 2.86e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs854765 0.565 rs854768 chr17:18018806 T/C cg04398451 chr17:18023971 MYO15A -0.77 -13.58 -0.59 6.9e-34 Total body bone mineral density; LIHC cis rs35306767 0.807 rs34982663 chr10:852521 C/G cg26597838 chr10:835615 NA 1.47 15.71 0.65 3.08e-42 Eosinophil percentage of granulocytes; LIHC cis rs6088580 0.634 rs6059880 chr20:33088669 G/A cg08999081 chr20:33150536 PIGU 0.67 13.37 0.59 4.49e-33 Glomerular filtration rate (creatinine); LIHC cis rs3806843 1.000 rs4451093 chr5:140158542 A/G cg19875535 chr5:140030758 IK -0.36 -5.83 -0.3 1.25e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs600806 0.850 rs3879452 chr1:109929237 G/A cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs1385374 0.858 rs10847696 chr12:129297153 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -5.76 -0.3 1.85e-8 Systemic lupus erythematosus; LIHC cis rs1005277 0.602 rs1780141 chr10:38504299 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs679087 0.932 rs10843506 chr12:29930883 G/A cg14258853 chr12:29935411 TMTC1 0.48 7.99 0.4 2.14e-14 Schizophrenia; LIHC cis rs9430161 0.611 rs34032547 chr1:11034374 C/G cg27631724 chr1:11040367 C1orf127 0.37 6.9 0.35 2.55e-11 Ewing sarcoma; LIHC cis rs11098499 0.954 rs11098524 chr4:120390032 A/G cg09307838 chr4:120376055 NA 0.81 12.38 0.56 2.51e-29 Corneal astigmatism; LIHC cis rs1577917 0.771 rs2475791 chr6:86368164 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -8.12 -0.4 8.27e-15 Response to antipsychotic treatment; LIHC cis rs3781458 0.803 rs10901793 chr10:126324209 G/A cg20435097 chr10:126320824 FAM53B 0.73 13.34 0.59 5.56e-33 Male-pattern baldness; LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.49 -0.33 3.03e-10 Total body bone mineral density; LIHC cis rs9980664 1.000 rs9975639 chr21:34736479 C/T cg04842828 chr21:34696676 IFNAR1 0.47 6.23 0.32 1.39e-9 Cognitive decline (age-related); LIHC cis rs7412746 0.658 rs897815 chr1:150879101 C/T cg17724175 chr1:150552817 MCL1 -0.38 -7.39 -0.37 1.15e-12 Melanoma; LIHC trans rs79976124 0.719 rs34488909 chr6:66637850 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 6.92 0.35 2.26e-11 Type 2 diabetes; LIHC cis rs9517313 0.592 rs61969458 chr13:99177633 A/G cg07423050 chr13:99094983 FARP1 -0.5 -8.8 -0.43 7.01e-17 Neuroticism; LIHC cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.84 0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs894734 0.535 rs10783613 chr12:54321966 G/T cg12374095 chr12:54320830 NA 0.46 7.05 0.36 9.75e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs41271473 0.539 rs763519 chr1:228892855 A/G cg00850481 chr1:228891306 NA 0.42 6.24 0.32 1.3e-9 Chronic lymphocytic leukemia; LIHC cis rs473651 0.935 rs477041 chr2:239355995 C/G cg21699342 chr2:239360505 ASB1 -0.34 -6.78 -0.34 5.14e-11 Multiple system atrophy; LIHC cis rs2839186 0.732 rs8131458 chr21:47694712 G/A cg00612595 chr21:47717864 NA -0.4 -6.57 -0.33 1.9e-10 Testicular germ cell tumor; LIHC cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg18225595 chr11:63971243 STIP1 0.66 8.28 0.41 2.87e-15 Mean platelet volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15617699 chr3:38538063 EXOG 0.43 6.16 0.32 2.1e-9 Lung function (FEV1/FVC); LIHC cis rs9916302 0.821 rs1966915 chr17:37425262 A/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.49 -0.59 1.55e-33 Glomerular filtration rate (creatinine); LIHC cis rs1048238 0.506 rs10927867 chr1:16177285 A/G cg00529422 chr1:16285251 ZBTB17 -0.34 -6.54 -0.33 2.19e-10 Systolic blood pressure; LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs9393692 0.645 rs28446029 chr6:26305801 C/G cg00631329 chr6:26305371 NA -0.5 -7.91 -0.39 3.69e-14 Educational attainment; LIHC cis rs919433 0.927 rs1429412 chr2:198190894 A/G cg03934865 chr2:198174659 NA -0.55 -8.65 -0.42 2.1e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs13394619 0.840 rs11674605 chr2:11722575 A/G cg07314298 chr2:11723111 GREB1 -0.52 -10.29 -0.49 7.93e-22 Endometriosis; LIHC cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs16828019 0.852 rs71648540 chr1:41722295 G/A cg03962019 chr1:41807865 NA 0.5 7.19 0.36 4.21e-12 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.610 rs7840469 chr8:58146992 C/T cg11062466 chr8:58055876 NA 0.41 6.26 0.32 1.14e-9 Developmental language disorder (linguistic errors); LIHC cis rs17152411 0.652 rs10901842 chr10:126635262 C/T cg07906193 chr10:126599966 NA 0.28 5.74 0.3 2.05e-8 Height; LIHC cis rs568617 0.953 rs658524 chr11:65647260 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.44 -0.33 4.17e-10 Crohn's disease; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg24503407 chr1:205819492 PM20D1 0.72 10.22 0.48 1.45e-21 Menarche (age at onset); LIHC cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg02931644 chr1:25747376 RHCE 0.35 7.7 0.38 1.43e-13 Erythrocyte sedimentation rate; LIHC cis rs17376456 1.000 rs12188453 chr5:93560807 G/T cg25358565 chr5:93447407 FAM172A -1.0 -9.54 -0.46 2.7e-19 Diabetic retinopathy; LIHC cis rs9457247 0.663 rs7749278 chr6:167435325 C/T cg23791538 chr6:167370224 RNASET2 0.63 10.46 0.49 2.2e-22 Crohn's disease; LIHC trans rs208520 0.690 rs851467 chr6:66802721 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.13 -0.44 5.97e-18 Exhaled nitric oxide output; LIHC cis rs11025559 0.773 rs16906274 chr11:20470142 T/C cg19653624 chr11:20408972 PRMT3 -0.48 -6.25 -0.32 1.2e-9 Pursuit maintenance gain; LIHC trans rs867371 0.896 rs6495647 chr15:82537049 C/G cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.14 -0.36 5.52e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs2739330 0.892 rs5751776 chr22:24266954 A/C cg06437703 chr8:37914619 EIF4EBP1 -0.53 -7.98 -0.4 2.23e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4764124 0.646 rs11610238 chr12:14975721 C/T cg19759883 chr12:14956454 WBP11;C12orf60 0.47 8.29 0.41 2.69e-15 Pubertal anthropometrics; LIHC cis rs1843834 0.539 rs6749402 chr2:225443901 T/G cg22455342 chr2:225449267 CUL3 0.61 8.86 0.43 4.31e-17 IgE levels in asthmatics (D.p. specific); LIHC cis rs6690583 0.524 rs12030837 chr1:85519383 A/G cg22153463 chr1:85462885 MCOLN2 -0.53 -6.5 -0.33 2.92e-10 Serum sulfate level; LIHC cis rs3749237 0.576 rs3877784 chr3:49539417 C/T cg02487422 chr3:49467188 NICN1 0.42 6.51 0.33 2.63e-10 Resting heart rate; LIHC cis rs243505 0.762 rs2007404 chr7:148487395 A/G cg09806900 chr7:148480153 CUL1 0.44 6.62 0.34 1.36e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2073300 1.000 rs6137967 chr20:23447108 A/T cg12062639 chr20:23401060 NAPB -0.75 -9.01 -0.44 1.43e-17 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs875971 1.000 rs6961155 chr7:65933295 T/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg12463550 chr7:65579703 CRCP 0.7 7.19 0.36 4.15e-12 Diabetic kidney disease; LIHC cis rs6432852 0.516 rs12477613 chr2:166717184 G/C cg15343463 chr2:166634454 GALNT3 0.37 5.97 0.31 5.99e-9 Diabetic kidney disease; LIHC cis rs3782089 1.000 rs11602375 chr11:65296540 C/T cg08676812 chr11:65308423 LTBP3 1.05 7.32 0.37 1.84e-12 Height; LIHC cis rs72627509 0.904 rs3796529 chr4:57797414 C/T cg26694713 chr4:57773883 REST 0.71 10.1 0.48 3.61e-21 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4808199 0.689 rs12979148 chr19:19406869 T/C cg03709012 chr19:19516395 GATAD2A 0.87 11.06 0.51 1.67e-24 Nonalcoholic fatty liver disease; LIHC cis rs3818285 0.679 rs2475275 chr10:111633979 C/T cg00817464 chr10:111662876 XPNPEP1 0.67 11.4 0.52 9.8e-26 Superior crus of antihelix expression; LIHC cis rs7208859 0.573 rs216442 chr17:28931197 T/G cg14067834 chr17:29058358 SUZ12P 0.66 6.64 0.34 1.26e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2303759 0.543 rs7255778 chr19:49906608 G/A cg24324837 chr19:49891574 CCDC155 0.4 6.35 0.32 6.71e-10 Multiple sclerosis; LIHC trans rs5756813 0.661 rs2285177 chr22:38205894 A/G cg19894588 chr14:64061835 NA -0.66 -10.09 -0.48 4.02e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs6570726 0.846 rs6899900 chr6:145883873 T/G cg23711669 chr6:146136114 FBXO30 0.65 11.61 0.53 1.74e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg08280861 chr8:58055591 NA 0.51 6.39 0.33 5.56e-10 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.82 8.55 0.42 4.11e-16 Platelet count; LIHC cis rs9733 0.596 rs12086630 chr1:150650955 T/C cg18016565 chr1:150552671 MCL1 0.59 11.57 0.53 2.34e-26 Tonsillectomy; LIHC cis rs4819052 0.851 rs1056099 chr21:46678892 G/A cg11663144 chr21:46675770 NA -0.3 -5.76 -0.3 1.84e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs886774 0.705 rs10271464 chr7:107579603 A/G cg27274322 chr4:1357073 KIAA1530 0.35 6.14 0.32 2.33e-9 Ulcerative colitis; LIHC cis rs7937682 0.961 rs4935790 chr11:111633014 T/C cg09085632 chr11:111637200 PPP2R1B 1.21 19.87 0.73 5.66e-59 Primary sclerosing cholangitis; LIHC cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.27 -0.45 2.12e-18 Bipolar disorder; LIHC trans rs6570726 0.516 rs9322025 chr6:145729196 C/T cg20452738 chr1:226828650 ITPKB -0.21 -6.08 -0.31 3.21e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12497850 0.829 rs12636030 chr3:49182237 A/G cg16497277 chr3:49208875 KLHDC8B -0.48 -5.77 -0.3 1.78e-8 Parkinson's disease; LIHC cis rs9926296 0.744 rs164746 chr16:89709019 C/T cg08949735 chr16:89699720 DPEP1 -0.46 -6.51 -0.33 2.63e-10 Vitiligo; LIHC cis rs9646954 0.542 rs11674830 chr2:101024735 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.36 0.41 1.64e-15 Intelligence (multi-trait analysis); LIHC cis rs847649 0.692 rs10271184 chr7:102477176 A/G cg18108683 chr7:102477205 FBXL13 -0.54 -8.61 -0.42 2.71e-16 Morning vs. evening chronotype; LIHC cis rs3780378 0.934 rs10815146 chr9:5015901 T/A cg02405213 chr9:5042618 JAK2 -0.55 -9.59 -0.46 1.95e-19 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs9916302 0.904 rs4795384 chr17:37716771 C/G cg07936489 chr17:37558343 FBXL20 -0.8 -12.61 -0.56 3.26e-30 Glomerular filtration rate (creatinine); LIHC cis rs921968 0.643 rs62191565 chr2:219482017 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.47 0.42 7.57e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs7659604 0.539 rs3217771 chr4:122739483 G/A cg20573242 chr4:122745356 CCNA2 0.51 7.52 0.38 4.93e-13 Type 2 diabetes; LIHC cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg19318889 chr4:1322082 MAEA 0.38 5.81 0.3 1.44e-8 Longevity; LIHC trans rs12080794 0.740 rs12726928 chr1:9190254 G/T cg16853660 chr11:32816211 CCDC73 -0.73 -6.54 -0.33 2.27e-10 Response to antidepressant treatment (citalopram); LIHC cis rs12249377 0.519 rs10785972 chr10:92593800 C/T cg14313238 chr10:92632228 RPP30 0.38 6.44 0.33 4.14e-10 White matter microstructure (global fractional anisotropy); LIHC cis rs1577917 1.000 rs12203493 chr6:86758642 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.04 -0.48 5.98e-21 Response to antipsychotic treatment; LIHC cis rs7927592 0.830 rs7120635 chr11:68261293 A/G cg20283391 chr11:68216788 NA -0.52 -7.91 -0.39 3.57e-14 Total body bone mineral density; LIHC cis rs9399135 0.844 rs13209789 chr6:135367916 A/G cg24558204 chr6:135376177 HBS1L 0.44 7.23 0.36 3.16e-12 Red blood cell count; LIHC cis rs12893668 0.572 rs35011804 chr14:104151400 C/T cg24130564 chr14:104152367 KLC1 -0.55 -9.53 -0.46 3.12e-19 Reticulocyte count; LIHC cis rs986417 0.901 rs1950310 chr14:60988526 T/A cg27398547 chr14:60952738 C14orf39 0.83 9.55 0.46 2.51e-19 Gut microbiota (bacterial taxa); LIHC cis rs9399135 0.967 rs7741515 chr6:135374368 C/G cg24558204 chr6:135376177 HBS1L -0.42 -6.55 -0.33 2.14e-10 Red blood cell count; LIHC cis rs17001868 0.892 rs12483888 chr22:40801312 A/G cg07138101 chr22:40742427 ADSL 0.55 5.77 0.3 1.82e-8 Mammographic density (dense area); LIHC cis rs9921222 0.521 rs11649255 chr16:357140 A/G cg26944245 chr16:421049 TMEM8A;MRPL28 0.38 6.5 0.33 2.83e-10 Bone mineral density (spine);Bone mineral density; LIHC cis rs67460515 0.531 rs13060601 chr3:160823159 G/A cg17135325 chr3:160939158 NMD3 0.55 7.64 0.38 2.15e-13 Parkinson's disease; LIHC trans rs1814175 0.817 rs6486044 chr11:49982718 C/T cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs6596100 0.554 rs12515756 chr5:132238880 T/C cg02081065 chr5:132209139 LEAP2 0.26 5.73 0.3 2.24e-8 Breast cancer; LIHC cis rs9399135 0.967 rs17638970 chr6:135320063 A/G cg24558204 chr6:135376177 HBS1L 0.4 6.65 0.34 1.15e-10 Red blood cell count; LIHC trans rs11088226 0.581 rs2833860 chr21:33882309 G/A cg09050820 chr6:167586206 TCP10L2 0.49 7.59 0.38 3.08e-13 Gastritis; LIHC cis rs6977660 1.000 rs10249989 chr7:19822296 A/G cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs9640161 0.750 rs11538922 chr7:150035183 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.55 -8.98 -0.44 1.8e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs11786130 1.000 rs62512839 chr8:129009401 A/G cg01765152 chr8:129005526 PVT1 -0.3 -6.33 -0.32 7.77e-10 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs1018836 0.828 rs4734250 chr8:91591239 C/G cg16814680 chr8:91681699 NA 0.52 8.44 0.42 9.39e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2455799 0.613 rs11713820 chr3:15866590 A/G cg12698662 chr3:15914712 MIR563 0.4 7.29 0.37 2.15e-12 Mean platelet volume; LIHC cis rs35110281 0.659 rs73367822 chr21:45024252 C/T cg04455712 chr21:45112962 RRP1B 0.43 7.26 0.37 2.56e-12 Mean corpuscular volume; LIHC cis rs1790761 0.667 rs4147581 chr11:67351585 C/G cg01069141 chr11:67398826 TBX10;NUDT8 0.36 6.5 0.33 2.78e-10 Mean corpuscular volume; LIHC cis rs2576037 0.583 rs11659693 chr18:44458733 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.98 0.51 3.15e-24 Personality dimensions; LIHC cis rs250677 0.687 rs2963484 chr5:148451127 A/T cg18129178 chr5:148520854 ABLIM3 -0.48 -7.42 -0.37 9.43e-13 Breast cancer; LIHC cis rs1005277 0.579 rs2505197 chr10:38393310 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs757110 0.868 rs5219 chr11:17409572 T/C cg15432903 chr11:17409602 KCNJ11 0.68 10.61 0.5 6.44e-23 Type 2 diabetes; LIHC cis rs2841277 0.741 rs9672139 chr14:105408182 T/G cg15352829 chr14:105391018 PLD4 -0.46 -9.94 -0.47 1.26e-20 Rheumatoid arthritis; LIHC cis rs2439831 1.000 rs537115 chr15:43729948 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.94 0.44 2.42e-17 Lung cancer in ever smokers; LIHC cis rs7903847 0.642 rs2275089 chr10:99141205 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10089 1.000 rs1864922 chr5:127420700 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.74 0.34 6.77e-11 Ileal carcinoids; LIHC cis rs8062405 0.755 rs62034358 chr16:28587597 G/T cg07382826 chr16:28625726 SULT1A1 0.5 7.73 0.39 1.19e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1712517 0.838 rs6584543 chr10:104997014 G/A cg05636881 chr10:105038444 INA -0.43 -6.94 -0.35 1.99e-11 Migraine; LIHC cis rs7172677 0.731 rs1108059 chr15:75338890 A/C cg17294928 chr15:75287854 SCAMP5 0.46 6.23 0.32 1.35e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05714094 chr11:117102988 RNF214;PCSK7 0.52 7.38 0.37 1.18e-12 Lung function (FEV1/FVC); LIHC cis rs2242116 0.896 rs724448 chr3:46935734 A/C cg23352942 chr3:46931381 PTH1R -0.33 -8.84 -0.43 4.97e-17 Birth weight; LIHC cis rs10508774 0.810 rs10508776 chr10:33189027 T/C cg01819863 chr10:32635814 EPC1 0.64 5.82 0.3 1.38e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs31251 0.900 rs11953786 chr5:131071440 A/T cg06307176 chr5:131281290 NA 0.36 5.75 0.3 2.03e-8 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs17428076 0.874 rs62182373 chr2:172685555 C/T cg13550731 chr2:172543902 DYNC1I2 0.39 6.32 0.32 8.02e-10 Myopia; LIHC cis rs11168351 0.517 rs10875754 chr12:48557922 G/C cg21466736 chr12:48725269 NA -0.33 -5.85 -0.3 1.16e-8 Bipolar disorder and schizophrenia; LIHC cis rs7546 0.505 rs760118 chr16:4940994 A/G cg08329684 chr16:4932620 PPL -0.42 -7.34 -0.37 1.61e-12 Cancer; LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.36 0.37 1.35e-12 Height; LIHC cis rs2839186 0.605 rs2839170 chr21:47671305 A/G cg00612595 chr21:47717864 NA -0.38 -6.32 -0.32 8.37e-10 Testicular germ cell tumor; LIHC cis rs67478160 0.643 rs11160762 chr14:104255083 A/G cg08213375 chr14:104286397 PPP1R13B -0.66 -12.99 -0.57 1.21e-31 Schizophrenia; LIHC cis rs7089973 0.604 rs11196936 chr10:116588630 C/T cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs950776 0.518 rs4243083 chr15:78833830 C/G cg22563815 chr15:78856949 CHRNA5 -0.37 -6.79 -0.34 5.02e-11 Sudden cardiac arrest; LIHC trans rs10982213 1.000 rs10817607 chr9:117179222 A/G cg13401823 chr1:204910715 NFASC 0.33 6.06 0.31 3.65e-9 Interleukin-6 levels; LIHC cis rs1580019 0.587 rs10951338 chr7:32560089 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.14 26.45 0.82 1.05e-84 Cognitive ability; LIHC cis rs763121 0.853 rs5757234 chr22:39072686 C/T cg06544989 chr22:39130855 UNC84B 0.36 5.89 0.3 9.2e-9 Menopause (age at onset); LIHC cis rs10870270 0.913 rs115236491 chr10:133766855 T/G cg17892150 chr10:133769511 PPP2R2D -0.69 -12.82 -0.57 5.37e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7772486 0.654 rs6928007 chr6:146074941 G/A cg23711669 chr6:146136114 FBXO30 -0.63 -11.45 -0.53 6.24e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9583531 0.600 rs4773241 chr13:111363021 A/G cg15841412 chr13:111365552 ING1 0.49 6.19 0.32 1.75e-9 Coronary artery disease; LIHC cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg08392591 chr16:89556376 ANKRD11 -0.5 -8.11 -0.4 9.04e-15 Multiple myeloma (IgH translocation); LIHC cis rs7772486 0.625 rs9390355 chr6:146112942 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -5.81 -0.3 1.45e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs59901009 0.815 rs10500721 chr11:10203610 A/G cg01453529 chr11:10209919 SBF2 -0.33 -6.58 -0.34 1.78e-10 Hematocrit;Hemoglobin concentration; LIHC cis rs7872515 0.793 rs10820936 chr9:94830974 C/T cg01248375 chr9:94877805 SPTLC1 -0.53 -7.77 -0.39 9.32e-14 Bipolar disorder and schizophrenia; LIHC cis rs4713118 0.824 rs2092075 chr6:27749330 G/C cg20933634 chr6:27740509 NA 0.45 5.95 0.31 6.71e-9 Parkinson's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05680085 chr2:227700568 RHBDD1 -0.49 -6.51 -0.33 2.73e-10 Pancreatic cancer; LIHC cis rs11971779 0.523 rs10279160 chr7:139090761 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs4718428 0.662 rs34577323 chr7:66310041 G/C cg18252515 chr7:66147081 NA -0.68 -9.28 -0.45 1.97e-18 Corneal structure; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg22528358 chr1:107598549 PRMT6 -0.69 -11.47 -0.53 5.69e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1691799 0.867 rs1168344 chr12:66758213 G/A cg16791601 chr12:66731901 HELB -0.54 -13.08 -0.58 5.56e-32 White blood cell count (basophil); LIHC cis rs7729447 0.566 rs3828591 chr5:32713108 G/C cg16267343 chr5:32710456 NPR3 0.5 6.32 0.32 8.34e-10 Blood pressure; LIHC cis rs11577318 0.796 rs4625269 chr1:26626967 C/A cg10402321 chr1:26617780 UBXN11 -0.38 -5.8 -0.3 1.48e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs2842992 0.872 rs2758315 chr6:160158640 T/C cg11366901 chr6:160182831 ACAT2 0.96 16.49 0.67 2.38e-45 Age-related macular degeneration (geographic atrophy); LIHC cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg16049864 chr8:95962084 TP53INP1 -0.64 -12.4 -0.56 2.04e-29 Type 2 diabetes; LIHC trans rs8026198 0.568 rs73403548 chr15:42443298 T/G cg03976788 chr22:43485480 TTLL1 0.72 6.22 0.32 1.43e-9 Fibrinogen levels; LIHC trans rs7395662 0.591 rs4882110 chr11:48558249 G/T cg15704280 chr7:45808275 SEPT13 -0.46 -6.89 -0.35 2.62e-11 HDL cholesterol; LIHC cis rs4660306 0.961 rs11211138 chr1:46015157 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.54 -6.48 -0.33 3.11e-10 Homocysteine levels; LIHC cis rs9814567 1.000 rs4974493 chr3:134219993 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.25 -0.55 7.24e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs611744 0.967 rs702802 chr8:109218238 G/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.77e-11 Dupuytren's disease; LIHC cis rs9399137 0.507 rs11759077 chr6:135381351 A/G cg24558204 chr6:135376177 HBS1L 0.64 10.67 0.5 4.01e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs7193541 0.585 rs7978 chr16:74486189 T/C cg01733217 chr16:74700730 RFWD3 -0.72 -13.9 -0.6 3.78e-35 Multiple myeloma; LIHC cis rs17818399 0.501 rs13413254 chr2:46802934 A/T cg02822958 chr2:46747628 ATP6V1E2 0.36 5.72 0.3 2.37e-8 Height; LIHC cis rs5770917 1.000 rs8137478 chr22:51017296 G/C cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.49 -6.07 -0.31 3.34e-9 Narcolepsy; LIHC cis rs17106184 1.000 rs10493149 chr1:50970475 A/G cg07174182 chr1:51127561 FAF1 -0.58 -6.32 -0.32 8.21e-10 Type 2 diabetes; LIHC cis rs17253792 0.598 rs71413578 chr14:56018651 T/C cg01858014 chr14:56050164 KTN1 -0.68 -6.2 -0.32 1.66e-9 Putamen volume; LIHC cis rs611744 0.517 rs62537573 chr8:109269281 C/T cg18478394 chr8:109455254 TTC35 0.4 6.79 0.34 5.1e-11 Dupuytren's disease; LIHC cis rs34779708 1.000 rs12769189 chr10:35399668 A/G cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs807029 0.533 rs12571302 chr10:102742763 C/A cg27255678 chr10:102756921 LZTS2 0.52 7.41 0.37 9.92e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs11098499 0.820 rs13128602 chr4:120459366 C/T cg25214090 chr10:38739885 LOC399744 -0.62 -10.07 -0.48 4.62e-21 Corneal astigmatism; LIHC cis rs36051895 0.623 rs11506292 chr9:5257048 C/A cg02405213 chr9:5042618 JAK2 -0.63 -10.12 -0.48 3.2e-21 Pediatric autoimmune diseases; LIHC cis rs796364 1.000 rs281762 chr2:200799201 C/G cg23649088 chr2:200775458 C2orf69 0.49 5.95 0.31 6.61e-9 Schizophrenia; LIHC cis rs3806843 0.735 rs801180 chr5:140092903 G/T cg16179182 chr5:140090404 VTRNA1-1 0.37 6.11 0.31 2.73e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7149337 1.000 rs4261445 chr14:51723540 G/A cg23942311 chr14:51606299 NA 0.35 6.79 0.34 5.02e-11 Cancer; LIHC trans rs11098499 0.866 rs11098506 chr4:120284971 A/G cg25214090 chr10:38739885 LOC399744 0.48 7.68 0.38 1.72e-13 Corneal astigmatism; LIHC cis rs7772486 0.776 rs2265467 chr6:146218339 T/A cg05347473 chr6:146136440 FBXO30 0.36 6.0 0.31 5.07e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs13191362 1.000 rs55822577 chr6:163069710 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.76 6.53 0.33 2.31e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs825937 0.818 rs825938 chr2:4807937 C/G cg16223976 chr13:33694703 STARD13 0.34 6.14 0.32 2.25e-9 Blood pressure; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg20102877 chr2:27665638 KRTCAP3 -0.44 -6.0 -0.31 5.02e-9 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27539627 chr3:122513065 DIRC2;HSPBAP1 0.48 6.87 0.35 3.11e-11 Pancreatic cancer; LIHC cis rs36051895 0.593 rs2094619 chr9:5167712 G/C cg02405213 chr9:5042618 JAK2 -0.75 -11.74 -0.54 5.74e-27 Pediatric autoimmune diseases; LIHC cis rs7635838 0.819 rs4684781 chr3:11516299 G/A cg00170343 chr3:11313890 ATG7 0.4 6.04 0.31 4.02e-9 HDL cholesterol; LIHC cis rs651907 0.557 rs35850993 chr3:101437433 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.02 0.51 2.21e-24 Colorectal cancer; LIHC cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg04267008 chr7:1944627 MAD1L1 -0.55 -8.54 -0.42 4.53e-16 Schizophrenia; LIHC cis rs2404602 0.647 rs118129828 chr15:77015200 T/C cg23625390 chr15:77176239 SCAPER -0.56 -9.51 -0.46 3.39e-19 Blood metabolite levels; LIHC cis rs9649465 1.000 rs627689 chr7:123400543 C/T cg03229431 chr7:123269106 ASB15 -0.39 -8.39 -0.41 1.25e-15 Migraine; LIHC cis rs7917772 0.565 rs61869210 chr10:104437175 A/C cg22532475 chr10:104410764 TRIM8 -0.38 -6.55 -0.33 2.09e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7582180 0.681 rs6754176 chr2:100995691 C/T cg14675211 chr2:100938903 LONRF2 0.56 8.23 0.41 4.08e-15 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.511 rs16921553 chr8:57979314 T/C cg11062466 chr8:58055876 NA 0.45 6.12 0.31 2.51e-9 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.616 rs6486011 chr11:49740230 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.81 0.35 4.37e-11 Height; LIHC cis rs1865760 0.623 rs12216125 chr6:25997458 C/T cg17691542 chr6:26056736 HIST1H1C 0.53 6.72 0.34 7.75e-11 Height; LIHC cis rs6939532 0.761 rs3799378 chr6:26404374 C/T cg09904177 chr6:26538194 HMGN4 0.4 6.13 0.31 2.37e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs34779708 0.966 rs4934736 chr10:35496868 G/A cg03585969 chr10:35415529 CREM 0.84 12.56 0.56 5.29e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 0.545 rs2420456 chr7:65745606 T/G cg11764359 chr7:65958608 NA 0.58 8.13 0.4 7.77e-15 Aortic root size; LIHC cis rs68170813 0.522 rs12531187 chr7:106963650 C/G cg02696742 chr7:106810147 HBP1 -0.5 -5.85 -0.3 1.17e-8 Coronary artery disease; LIHC cis rs600806 0.888 rs444387 chr1:109851127 A/G cg08911820 chr1:110026001 ATXN7L2 -0.58 -6.81 -0.35 4.51e-11 Intelligence (multi-trait analysis); LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg01171360 chr6:293285 DUSP22 -0.5 -7.68 -0.38 1.73e-13 Menopause (age at onset); LIHC cis rs2073300 1.000 rs6048811 chr20:23446719 G/C cg12062639 chr20:23401060 NAPB 0.82 9.64 0.46 1.31e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9902453 1.000 rs7207021 chr17:28400516 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.99 -0.54 7.08e-28 Coffee consumption (cups per day); LIHC cis rs11792861 0.566 rs11792635 chr9:111848819 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.46 6.61 0.34 1.51e-10 Menarche (age at onset); LIHC cis rs34779708 0.931 rs59418206 chr10:35331624 G/A cg04310649 chr10:35416472 CREM -0.43 -5.83 -0.3 1.31e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11122272 0.668 rs2472261 chr1:231505701 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -10.15 -0.48 2.46e-21 Hemoglobin concentration; LIHC cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg05552183 chr6:42928497 GNMT 0.65 9.5 0.46 3.88e-19 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs7618501 1.000 rs11716575 chr3:49744890 A/G cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs9457247 1.000 rs2757042 chr6:167371234 A/T cg12798992 chr6:167411361 FGFR1OP -0.54 -8.19 -0.41 5.08e-15 Crohn's disease; LIHC cis rs1434579 0.798 rs12460231 chr19:44954688 A/T cg15540054 chr19:45004280 ZNF180 0.63 8.65 0.42 2.03e-16 Tuberculosis; LIHC cis rs3818285 1.000 rs3740138 chr10:111630931 C/T cg00817464 chr10:111662876 XPNPEP1 -0.4 -6.08 -0.31 3.22e-9 Superior crus of antihelix expression; LIHC cis rs12701220 0.655 rs7799656 chr7:1140515 C/T cg04498913 chr7:1135747 C7orf50 0.43 6.9 0.35 2.51e-11 Bronchopulmonary dysplasia; LIHC cis rs7772486 0.875 rs2748497 chr6:146319417 C/T cg13319975 chr6:146136371 FBXO30 -0.37 -6.24 -0.32 1.3e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs208520 0.837 rs208486 chr6:66926255 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.23 -0.41 4e-15 Exhaled nitric oxide output; LIHC cis rs10751667 0.666 rs12295141 chr11:947065 G/A cg06064525 chr11:970664 AP2A2 -0.56 -15.07 -0.63 1.01e-39 Alzheimer's disease (late onset); LIHC cis rs1799949 0.930 rs1554063 chr17:41287145 T/C cg23758822 chr17:41437982 NA 0.91 16.8 0.67 1.33e-46 Menopause (age at onset); LIHC cis rs3096299 0.933 rs2965823 chr16:89454924 G/A cg02187348 chr16:89574699 SPG7 0.5 7.48 0.38 6.19e-13 Multiple myeloma (IgH translocation); LIHC cis rs7618501 0.669 rs7634084 chr3:49949834 A/T cg21467203 chr3:49911342 NA -0.48 -8.62 -0.42 2.55e-16 Intelligence (multi-trait analysis); LIHC cis rs11190604 1.000 rs76683169 chr10:102358397 A/T cg07080220 chr10:102295463 HIF1AN 0.55 6.94 0.35 2.03e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10791097 0.694 rs12361892 chr11:130744490 T/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs77633900 0.772 rs79181196 chr15:76656281 G/T cg21673338 chr15:77095150 SCAPER -0.53 -6.15 -0.32 2.15e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs5769707 0.904 rs7288869 chr22:50015327 C/T cg07959070 chr22:50026188 C22orf34 -0.33 -8.63 -0.42 2.4e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs66569888 0.632 rs6728600 chr2:106898653 G/T cg15412446 chr2:106886593 NA -0.72 -6.94 -0.35 1.98e-11 Facial morphology (factor 23); LIHC cis rs4862307 0.836 rs4507404 chr4:185003767 C/T cg06737308 chr4:185021514 ENPP6 -0.41 -6.14 -0.32 2.31e-9 Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg20607798 chr8:58055168 NA 0.63 7.79 0.39 7.84e-14 Developmental language disorder (linguistic errors); LIHC trans rs459571 0.920 rs460154 chr9:136909309 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.51 -8.0 -0.4 1.9e-14 Platelet distribution width; LIHC cis rs17826219 0.500 rs57005940 chr17:29066329 C/G cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27119451 chr5:137514611 BRD8;KIF20A 0.46 6.62 0.34 1.35e-10 Pancreatic cancer; LIHC cis rs13108904 0.901 rs6851528 chr4:1296009 G/A cg16405210 chr4:1374714 KIAA1530 -0.56 -8.61 -0.42 2.69e-16 Obesity-related traits; LIHC cis rs769267 0.930 rs7254927 chr19:19404786 C/G cg03709012 chr19:19516395 GATAD2A 0.94 15.76 0.65 1.93e-42 Tonsillectomy; LIHC cis rs7106204 0.609 rs12785699 chr11:24280489 C/T ch.11.24196551F chr11:24239977 NA 0.7 6.38 0.33 5.61e-10 Response to Homoharringtonine (cytotoxicity); LIHC cis rs7772486 0.875 rs1929523 chr6:146339989 T/A cg13319975 chr6:146136371 FBXO30 -0.37 -6.1 -0.31 2.9e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg05983323 chr4:166249203 SC4MOL -0.4 -6.11 -0.31 2.73e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2742417 0.609 rs2673066 chr3:45771200 C/T cg04837898 chr3:45731254 SACM1L -0.51 -8.63 -0.42 2.4e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs7618501 0.570 rs7613875 chr3:49971514 C/A cg24110177 chr3:50126178 RBM5 -0.48 -7.6 -0.38 2.96e-13 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02002494 chr3:119013045 CDGAP 0.45 6.74 0.34 6.56e-11 Pancreatic cancer; LIHC cis rs9297145 0.585 rs10953281 chr7:98772131 C/T cg05967295 chr7:98741636 SMURF1 -0.37 -6.2 -0.32 1.63e-9 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs875971 0.862 rs2909688 chr7:65841612 C/A cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.7 -0.34 8.47e-11 Lymphocyte counts; LIHC cis rs79387448 0.745 rs7575867 chr2:103120179 C/T cg09003973 chr2:102972529 NA 0.8 7.0 0.35 1.34e-11 Gut microbiota (bacterial taxa); LIHC cis rs1904096 0.506 rs10028613 chr4:95223698 T/C cg11021082 chr4:95130006 SMARCAD1 -0.47 -8.09 -0.4 1.03e-14 Type 2 diabetes; LIHC cis rs7927771 0.524 rs7932703 chr11:47769936 A/C cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg10862848 chr6:42927986 GNMT -0.26 -6.37 -0.33 6.27e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg22903471 chr2:27725779 GCKR -0.46 -7.92 -0.39 3.38e-14 Total body bone mineral density; LIHC cis rs8084351 0.577 rs4530205 chr18:50658914 G/A cg24270629 chr18:50823537 DCC -0.44 -6.47 -0.33 3.3e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7903847 0.642 rs10882910 chr10:99138043 G/A cg08345082 chr10:99160200 RRP12 -0.38 -6.25 -0.32 1.23e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1048238 0.548 rs848217 chr1:16272250 A/G cg00529422 chr1:16285251 ZBTB17 0.31 6.04 0.31 4.09e-9 Systolic blood pressure; LIHC cis rs35110281 0.744 rs230646 chr21:44918788 A/G cg04455712 chr21:45112962 RRP1B 0.46 7.4 0.37 1.03e-12 Mean corpuscular volume; LIHC trans rs1005277 0.522 rs1208767 chr10:38042295 G/T cg23533926 chr12:111358616 MYL2 -0.32 -6.25 -0.32 1.23e-9 Extrinsic epigenetic age acceleration; LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg10774155 chr7:65338427 VKORC1L1 -0.44 -6.57 -0.33 1.83e-10 Calcium levels; LIHC cis rs60871478 0.898 rs4725241 chr7:796883 C/T cg13844804 chr7:814759 HEATR2 0.44 5.95 0.31 6.62e-9 Cerebrospinal P-tau181p levels; LIHC cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.54 0.33 2.18e-10 Bipolar disorder; LIHC cis rs7677751 0.767 rs7676985 chr4:55064573 G/A cg17187183 chr4:55093834 PDGFRA 0.58 7.32 0.37 1.83e-12 Corneal astigmatism; LIHC cis rs919433 0.783 rs55725278 chr2:198238223 C/T cg10820045 chr2:198174542 NA 0.56 9.01 0.44 1.46e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1707322 0.663 rs3935296 chr1:46180470 T/C cg03146154 chr1:46216737 IPP -0.6 -10.31 -0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg14527280 chr6:3458119 SLC22A23 0.45 6.24 0.32 1.32e-9 Alopecia areata; LIHC cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg05665937 chr4:1216051 CTBP1 0.43 5.73 0.3 2.26e-8 Obesity-related traits; LIHC cis rs74233809 1.000 rs12221193 chr10:104665267 A/C cg03493300 chr10:104813866 CNNM2 0.46 6.11 0.31 2.68e-9 Birth weight; LIHC cis rs5769707 0.632 rs135871 chr22:50008969 A/G cg01652190 chr22:50026171 C22orf34 -0.33 -7.4 -0.37 1.03e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg08888203 chr3:10149979 C3orf24 0.54 6.27 0.32 1.06e-9 Alzheimer's disease; LIHC cis rs6665290 0.904 rs6677602 chr1:227187838 G/T cg10327440 chr1:227177885 CDC42BPA -1.09 -22.18 -0.77 3.7e-68 Myeloid white cell count; LIHC cis rs760762 0.636 rs6129801 chr20:39916437 T/C cg06424997 chr20:39929561 ZHX3 0.35 5.73 0.3 2.2e-8 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; LIHC cis rs8062405 0.755 rs4149398 chr16:28608938 C/G cg07382826 chr16:28625726 SULT1A1 0.5 7.69 0.38 1.61e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7617773 0.817 rs745116 chr3:48272536 T/G cg11946769 chr3:48343235 NME6 0.86 11.07 0.51 1.46e-24 Coronary artery disease; LIHC cis rs7395581 0.918 rs10742799 chr11:47293702 T/C cg26139080 chr11:47293733 MADD -0.5 -8.33 -0.41 1.92e-15 HDL cholesterol; LIHC cis rs11628318 0.539 rs57749886 chr14:103095652 C/T cg12046867 chr14:103022105 NA -0.42 -6.6 -0.34 1.54e-10 Platelet count; LIHC cis rs3213545 0.659 rs2259693 chr12:121457995 G/A cg15155738 chr12:121454335 C12orf43 0.47 6.75 0.34 6.46e-11 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs6546550 0.868 rs12713682 chr2:70154134 G/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.63 -0.38 2.31e-13 Prevalent atrial fibrillation; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg22575458 chr10:5667028 NA 0.42 6.49 0.33 2.94e-10 Longevity; LIHC cis rs10751667 0.577 rs7946461 chr11:974035 A/G cg06064525 chr11:970664 AP2A2 -0.56 -14.83 -0.63 8.92e-39 Alzheimer's disease (late onset); LIHC cis rs9354308 0.932 rs1938061 chr6:66545581 A/C cg07460842 chr6:66804631 NA -0.5 -5.96 -0.31 6.42e-9 Metabolite levels; LIHC cis rs826838 0.935 rs1684407 chr12:39127270 C/T cg26384229 chr12:38710491 ALG10B -0.61 -8.98 -0.44 1.87e-17 Heart rate; LIHC cis rs11098499 0.954 rs13133522 chr4:120324424 A/T cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs4253772 0.938 rs9626814 chr22:46637254 C/T cg09491104 chr22:46646882 C22orf40 -0.55 -5.85 -0.3 1.12e-8 LDL cholesterol;Cholesterol, total; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08510077 chr3:113666901 ZDHHC23 0.36 6.09 0.31 2.98e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7091068 0.754 rs1326224 chr10:95459267 C/T cg20715218 chr10:95462985 C10orf4 0.62 6.82 0.35 4.07e-11 Urinary tract infection frequency; LIHC cis rs798554 0.757 rs2644312 chr7:2841164 G/A cg19717773 chr7:2847554 GNA12 -0.41 -6.56 -0.33 1.96e-10 Height; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg02864619 chr17:78933961 RPTOR 0.44 6.74 0.34 6.75e-11 Bilirubin levels; LIHC cis rs11711311 1.000 rs13073843 chr3:113449150 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.39 0.45 8.39e-19 IgG glycosylation; LIHC cis rs11122272 0.735 rs2572253 chr1:231512768 C/A cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.09e-18 Hemoglobin concentration; LIHC cis rs17106184 0.892 rs72902768 chr1:51261965 C/T cg07174182 chr1:51127561 FAF1 -0.64 -6.96 -0.35 1.75e-11 Type 2 diabetes; LIHC cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.98 0.31 5.74e-9 Menopause (age at onset); LIHC cis rs6430585 0.528 rs12464050 chr2:136663110 G/T cg07305463 chr2:136567211 LCT -0.39 -6.04 -0.31 3.94e-9 Corneal structure; LIHC cis rs1143633 0.530 rs4538207 chr2:113701863 G/T cg12858261 chr2:113808755 IL1F8 0.34 5.94 0.31 7.18e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs8114671 0.562 rs6088636 chr20:33469746 C/T cg07148914 chr20:33460835 GGT7 0.64 9.75 0.47 5.44e-20 Height; LIHC cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.54 -0.5 1.09e-22 Platelet count; LIHC cis rs1552244 0.882 rs6443279 chr3:10053599 C/A cg08888203 chr3:10149979 C3orf24 0.49 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC cis rs8017423 1.000 rs8015379 chr14:90679432 C/T cg04374321 chr14:90722782 PSMC1 0.73 14.04 0.6 1.1e-35 Mortality in heart failure; LIHC cis rs3020736 0.500 rs4147640 chr22:42485292 T/C cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg06634786 chr22:41940651 POLR3H -0.79 -8.69 -0.43 1.55e-16 Vitiligo; LIHC cis rs17021463 0.902 rs2865352 chr4:95253263 A/G cg11021082 chr4:95130006 SMARCAD1 -0.45 -8.08 -0.4 1.09e-14 Testicular germ cell tumor; LIHC cis rs546131 0.642 rs537873 chr11:34835121 A/G cg06937548 chr11:34938143 PDHX;APIP 0.57 7.28 0.37 2.28e-12 Lung disease severity in cystic fibrosis; LIHC cis rs9902453 0.791 rs2729451 chr17:28131334 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -11.78 -0.54 4.01e-27 Coffee consumption (cups per day); LIHC cis rs2637266 0.626 rs1660914 chr10:78525319 T/A cg18941641 chr10:78392320 NA 0.28 6.05 0.31 3.77e-9 Pulmonary function; LIHC cis rs11077998 0.935 rs9893826 chr17:80511128 C/T cg10255544 chr17:80519551 FOXK2 0.49 8.97 0.44 1.96e-17 Reticulocyte fraction of red cells; LIHC cis rs6933660 0.800 rs963193 chr6:151789355 G/T cg14416726 chr6:151773293 C6orf211;RMND1 0.52 7.73 0.39 1.23e-13 Menarche (age at onset); LIHC cis rs2075671 0.903 rs4727459 chr7:100276821 T/C cg20848291 chr7:100343083 ZAN -0.47 -6.64 -0.34 1.23e-10 Other erythrocyte phenotypes; LIHC cis rs1816752 0.870 rs9581025 chr13:24997825 T/C cg22771759 chr13:24902376 NA 0.32 6.49 0.33 3.03e-10 Obesity-related traits; LIHC cis rs713477 0.654 rs61976568 chr14:55906218 A/G cg13175173 chr14:55914753 NA -0.31 -6.75 -0.34 6.39e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs16866061 1.000 rs11686590 chr2:225334070 A/G cg12698349 chr2:225449008 CUL3 0.73 12.65 0.56 2.27e-30 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs4728302 0.869 rs12707128 chr7:133589796 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.38 0.33 5.64e-10 Intelligence;Intelligence (multi-trait analysis); LIHC trans rs11098499 0.909 rs78332141 chr4:120375782 C/T cg25214090 chr10:38739885 LOC399744 0.62 9.85 0.47 2.67e-20 Corneal astigmatism; LIHC cis rs60871478 1.000 rs4397290 chr7:828493 T/C cg27478167 chr7:817139 HEATR2 0.4 5.82 0.3 1.37e-8 Cerebrospinal P-tau181p levels; LIHC cis rs8180040 0.701 rs7617689 chr3:46996442 C/T cg16586182 chr3:47516702 SCAP 0.46 8.26 0.41 3.21e-15 Colorectal cancer; LIHC cis rs8077889 0.956 rs55768269 chr17:41888997 C/T cg26893861 chr17:41843967 DUSP3 0.98 10.83 0.51 1.06e-23 Triglycerides; LIHC cis rs9916302 0.904 rs7223331 chr17:37482930 A/G cg07936489 chr17:37558343 FBXL20 0.84 13.59 0.59 6.04e-34 Glomerular filtration rate (creatinine); LIHC cis rs15676 0.812 rs10819447 chr9:131576416 T/G cg13708974 chr9:131466143 PKN3 0.37 5.71 0.3 2.43e-8 Blood metabolite levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg00429477 chr12:6798907 ZNF384 -0.54 -6.5 -0.33 2.87e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs17376456 0.825 rs10079708 chr5:93261796 G/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs1707322 0.682 rs3014241 chr1:46087879 A/G cg03146154 chr1:46216737 IPP -0.55 -9.11 -0.44 7.26e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs116095464 0.558 rs10055405 chr5:265666 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.67 -0.5 4.06e-23 Breast cancer; LIHC cis rs1274963 0.601 rs2063634 chr3:39196452 A/G cg02254461 chr3:39195904 CSRNP1 -0.48 -5.84 -0.3 1.23e-8 Chronic lymphocytic leukemia; LIHC cis rs9486719 1.000 rs34209750 chr6:96882215 G/T cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs9399135 0.967 rs13191501 chr6:135366880 T/C cg22676075 chr6:135203613 NA 0.4 6.4 0.33 5.05e-10 Red blood cell count; LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.4 0.81 1.03e-80 Prudent dietary pattern; LIHC cis rs57502260 0.573 rs12291008 chr11:68389072 T/C cg16797656 chr11:68205561 LRP5 0.45 6.72 0.34 7.41e-11 Total body bone mineral density (age 45-60); LIHC cis rs2549003 1.000 rs2070722 chr5:131824486 A/C cg02551604 chr5:131831745 NA -0.49 -7.59 -0.38 3.01e-13 Asthma (sex interaction); LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg27411370 chr8:25316735 KCTD9;CDCA2 -0.43 -6.05 -0.31 3.77e-9 Monocyte count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00349413 chr17:48171948 PDK2 0.45 7.05 0.36 9.97e-12 Cognitive function; LIHC cis rs4654899 0.897 rs59537090 chr1:21498737 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.79 0.3 1.63e-8 Superior frontal gyrus grey matter volume; LIHC cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.72 12.32 0.55 4.1e-29 Colorectal cancer; LIHC cis rs561341 1.000 rs113676348 chr17:30244327 A/G cg12193833 chr17:30244370 NA -0.57 -6.03 -0.31 4.19e-9 Hip circumference adjusted for BMI; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg06873352 chr17:61820015 STRADA 0.71 12.19 0.55 1.27e-28 Prudent dietary pattern; LIHC cis rs77633900 0.772 rs8031378 chr15:76657874 A/G cg21673338 chr15:77095150 SCAPER -0.5 -5.95 -0.31 6.72e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs910316 0.763 rs175044 chr14:75472109 G/A cg08847533 chr14:75593920 NEK9 -0.87 -17.46 -0.69 2.88e-49 Height; LIHC cis rs743757 1.000 rs734767 chr3:50431410 C/G cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.29 0.32 9.57e-10 Diastolic blood pressure; LIHC cis rs4975616 0.686 rs37008 chr5:1351538 C/T cg07493874 chr5:1342172 CLPTM1L -0.54 -8.26 -0.41 3.22e-15 Lung cancer; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg16427488 chr8:86132835 C8orf59 -0.43 -6.2 -0.32 1.65e-9 Body mass index; LIHC cis rs2625529 0.938 rs4777464 chr15:72131763 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.86 -0.3 1.12e-8 Red blood cell count; LIHC cis rs798554 0.642 rs2533871 chr7:2883006 C/G cg13628971 chr7:2884303 GNA12 0.6 10.11 0.48 3.41e-21 Height; LIHC cis rs240764 0.817 rs239211 chr6:101144965 A/C cg09795085 chr6:101329169 ASCC3 0.5 6.8 0.34 4.8e-11 Neuroticism; LIHC cis rs7903847 0.642 rs11189183 chr10:99144321 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs8062405 0.698 rs7188071 chr16:28917644 T/C cg00204512 chr16:28754710 NA -0.34 -6.12 -0.31 2.61e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9467773 1.000 rs10214634 chr6:26564582 T/A cg09904177 chr6:26538194 HMGN4 0.66 13.84 0.6 6.58e-35 Intelligence (multi-trait analysis); LIHC cis rs3762637 0.943 rs9289199 chr3:122277172 G/A cg24169773 chr3:122142474 KPNA1 -0.45 -9.01 -0.44 1.49e-17 LDL cholesterol levels; LIHC cis rs7072216 0.763 rs6584204 chr10:100173580 C/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs11690935 0.851 rs10930502 chr2:172890588 A/G cg13550731 chr2:172543902 DYNC1I2 -0.5 -8.03 -0.4 1.59e-14 Schizophrenia; LIHC cis rs909341 0.909 rs2872881 chr20:62342801 G/A cg03999872 chr20:62272968 STMN3 -0.45 -6.78 -0.34 5.24e-11 Atopic dermatitis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02030672 chr11:45687055 CHST1 0.41 6.31 0.32 8.64e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs877282 0.797 rs35927768 chr10:753095 T/C cg22713356 chr15:30763199 NA 1.36 11.83 0.54 2.74e-27 Uric acid levels; LIHC cis rs939574 0.929 rs10190834 chr2:220070301 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.96 -10.46 -0.49 2.05e-22 Platelet distribution width; LIHC cis rs7412746 0.611 rs66847267 chr1:150875173 C/A cg15448220 chr1:150897856 SETDB1 0.38 6.13 0.31 2.48e-9 Melanoma; LIHC cis rs1878931 0.507 rs11648783 chr16:3406626 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.65 8.5 0.42 5.81e-16 Body mass index (adult); LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg10755058 chr3:40428713 ENTPD3 0.41 7.04 0.36 1.04e-11 Renal cell carcinoma; LIHC cis rs1000083 0.704 rs1830366 chr5:96591215 C/T ch.5.96698337R chr5:96672581 NA 0.84 6.84 0.35 3.68e-11 Cisplatin-induced ototoxicity; LIHC cis rs7666738 0.512 rs165251 chr4:98758490 C/G cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs4478037 0.818 rs17522946 chr3:33138777 A/G cg16652328 chr3:33138982 GLB1;TMPPE -0.52 -6.68 -0.34 9.44e-11 Major depressive disorder; LIHC cis rs10870270 0.956 rs11146425 chr10:133734261 C/T cg17892150 chr10:133769511 PPP2R2D -0.69 -13.16 -0.58 2.7e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7224737 1.000 rs9912088 chr17:40288278 T/C cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs9921222 0.502 rs28461430 chr16:369562 G/A cg12437481 chr16:420112 MRPL28 -0.63 -8.45 -0.42 8.64e-16 Bone mineral density (spine);Bone mineral density; LIHC cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs5758659 0.819 rs134871 chr22:42652716 A/G cg19513890 chr22:42538836 CYP2D7P1 -0.31 -6.14 -0.32 2.28e-9 Cognitive function; LIHC cis rs1801251 1.000 rs7558609 chr2:233700379 C/T cg25237894 chr2:233734115 C2orf82 0.58 11.28 0.52 2.71e-25 Coronary artery disease; LIHC cis rs9549328 0.842 rs6577024 chr13:113634091 G/C cg18289306 chr13:113640169 MCF2L 0.41 6.58 0.34 1.75e-10 Systolic blood pressure; LIHC cis rs7582720 1.000 rs72936873 chr2:203791333 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7100689 0.646 rs10736356 chr10:82148325 A/G cg01528321 chr10:82214614 TSPAN14 0.84 11.77 0.54 4.32e-27 Post bronchodilator FEV1; LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg12379764 chr21:47803548 PCNT -0.59 -8.88 -0.43 3.88e-17 Testicular germ cell tumor; LIHC cis rs1580019 0.563 rs4723169 chr7:32567577 G/A cg14728415 chr7:32535168 LSM5;AVL9 0.42 5.92 0.3 7.78e-9 Cognitive ability; LIHC cis rs9783347 0.857 rs4150561 chr11:18354877 T/C cg15585147 chr11:18324498 HPS5 0.43 6.73 0.34 6.95e-11 Pancreatic cancer; LIHC cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg04267008 chr7:1944627 MAD1L1 -0.59 -9.33 -0.45 1.41e-18 Bipolar disorder and schizophrenia; LIHC cis rs17376456 0.877 rs9314100 chr5:93447394 T/C cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs1165668 1.000 rs10778305 chr12:104311974 C/G cg21863207 chr12:104234989 NT5DC3 0.4 6.39 0.33 5.53e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs9308433 0.505 rs6695148 chr1:214497861 G/T cg06198575 chr1:214491504 SMYD2 0.56 5.92 0.3 7.86e-9 IgG glycosylation; LIHC cis rs7412746 0.658 rs1546376 chr1:150937661 A/G cg15448220 chr1:150897856 SETDB1 0.44 6.94 0.35 1.97e-11 Melanoma; LIHC cis rs875971 0.862 rs10278014 chr7:66051264 C/T cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.22e-34 Aortic root size; LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg00612595 chr21:47717864 NA -0.4 -6.77 -0.34 5.52e-11 Testicular germ cell tumor; LIHC trans rs2243480 0.808 rs12698508 chr7:65411958 A/T cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs57590327 0.555 rs13084107 chr3:81833577 T/C cg07356753 chr3:81810745 GBE1 -0.57 -8.92 -0.43 2.94e-17 Extraversion; LIHC cis rs7684446 1 rs7684446 chr4:15592864 C/T cg21123203 chr4:15471301 CC2D2A 0.39 6.54 0.33 2.22e-10 Red blood cell count; LIHC cis rs3806843 0.966 rs2337516 chr5:140140853 A/G cg19875535 chr5:140030758 IK -0.38 -6.23 -0.32 1.39e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2842992 0.872 rs1570318 chr6:160111473 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.12 0.55 2.27e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs2404602 0.735 rs2461871 chr15:76822418 C/G cg03037974 chr15:76606532 NA -0.58 -9.93 -0.47 1.4e-20 Blood metabolite levels; LIHC cis rs1538970 1.000 rs4660852 chr1:45848931 A/C cg05343316 chr1:45956843 TESK2 -0.59 -9.04 -0.44 1.21e-17 Platelet count; LIHC cis rs2832191 0.716 rs2692625 chr21:30446360 C/G cg24692254 chr21:30365293 RNF160 0.87 15.64 0.65 5.61e-42 Dental caries; LIHC cis rs2637266 1.000 rs7914880 chr10:78363693 A/G cg18941641 chr10:78392320 NA 0.3 6.5 0.33 2.92e-10 Pulmonary function; LIHC cis rs7927771 0.801 rs12798028 chr11:47604639 C/T cg20135002 chr11:47629003 NA -0.52 -9.15 -0.44 5.22e-18 Subjective well-being; LIHC cis rs1451375 0.652 rs10265930 chr7:50627449 C/T cg14593290 chr7:50529359 DDC 0.51 7.9 0.39 3.94e-14 Malaria; LIHC cis rs17253792 0.731 rs79483151 chr14:56048851 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs1144333 1.000 rs12078893 chr1:76370862 T/C cg03433033 chr1:76189801 ACADM 0.54 8.03 0.4 1.61e-14 Attention function in attention deficit hyperactive disorder; LIHC cis rs4555082 0.834 rs2735816 chr14:105721603 C/G cg06808227 chr14:105710500 BRF1 0.61 8.56 0.42 3.78e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs7586673 0.930 rs2884364 chr2:161977647 G/A cg22496339 chr2:162101262 NA 0.7 10.6 0.5 6.79e-23 Intelligence (multi-trait analysis); LIHC cis rs9814567 0.896 rs2177602 chr3:134245866 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7829975 0.593 rs2921061 chr8:8317615 A/T cg06636001 chr8:8085503 FLJ10661 0.72 11.24 0.52 3.76e-25 Mood instability; LIHC trans rs875971 1.000 rs4718343 chr7:65874288 T/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs2075371 0.966 rs2244690 chr7:133987039 A/G cg11752832 chr7:134001865 SLC35B4 0.52 7.83 0.39 6.14e-14 Mean platelet volume; LIHC cis rs919433 0.963 rs4850429 chr2:198178409 A/G cg03934865 chr2:198174659 NA 0.57 9.09 0.44 8.33e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8016982 0.662 rs1864169 chr14:81670033 G/T cg01989461 chr14:81687754 GTF2A1 0.52 9.1 0.44 7.41e-18 Schizophrenia; LIHC cis rs2976388 0.609 rs2585149 chr8:143793320 T/C cg06565975 chr8:143823917 SLURP1 0.33 6.38 0.33 5.67e-10 Urinary tract infection frequency; LIHC cis rs4728302 0.869 rs10808273 chr7:133597691 G/C cg10665199 chr7:133106180 EXOC4 0.38 6.64 0.34 1.21e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs903552 0.736 rs11858491 chr15:102007456 C/T cg25677261 chr15:102009856 PCSK6 0.49 6.87 0.35 3.13e-11 Diabetic kidney disease; LIHC cis rs4665809 0.878 rs6720312 chr2:26364934 A/G cg04944784 chr2:26401820 FAM59B 0.68 8.68 0.42 1.64e-16 Gut microbiome composition (summer); LIHC cis rs7208859 0.573 rs28779471 chr17:29084369 T/C cg14067834 chr17:29058358 SUZ12P 0.69 6.86 0.35 3.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6570726 0.791 rs11759979 chr6:145918881 C/T cg23711669 chr6:146136114 FBXO30 0.73 12.13 0.55 2.16e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg07308232 chr7:1071921 C7orf50 -0.48 -7.84 -0.39 5.62e-14 Longevity;Endometriosis; LIHC cis rs1577917 1.000 rs34622557 chr6:86630852 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC trans rs10982213 0.514 rs10739411 chr9:117183149 C/T cg13401823 chr1:204910715 NFASC -0.32 -6.18 -0.32 1.82e-9 Interleukin-6 levels; LIHC cis rs10197940 0.578 rs2432956 chr2:152287831 C/T cg06191203 chr2:152266755 RIF1 0.58 9.04 0.44 1.16e-17 Lung cancer; LIHC cis rs7089973 0.604 rs11196947 chr10:116601372 G/A cg23260525 chr10:116636907 FAM160B1 0.36 7.09 0.36 7.74e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2836974 0.583 rs2735307 chr21:40713358 C/T cg11890956 chr21:40555474 PSMG1 0.58 8.75 0.43 9.58e-17 Cognitive function; LIHC cis rs61861422 0.516 rs12412216 chr10:134393338 C/T cg27286337 chr10:134555280 INPP5A 0.53 6.87 0.35 3.07e-11 Primary sclerosing cholangitis; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg06420487 chr17:61919686 SMARCD2 0.43 5.79 0.3 1.62e-8 Height; LIHC cis rs2991971 1.000 rs2993262 chr1:46013733 G/C cg24296786 chr1:45957014 TESK2 0.5 7.29 0.37 2.22e-12 High light scatter reticulocyte count; LIHC cis rs11030122 0.702 rs995498 chr11:3967791 A/G cg18678763 chr11:4115507 RRM1 -0.57 -8.56 -0.42 3.98e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs644799 1.000 rs623191 chr11:95548359 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.14 0.68 5.42e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg21280719 chr6:42927975 GNMT -0.31 -6.92 -0.35 2.19e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg12373951 chr3:133503437 NA 0.56 9.51 0.46 3.41e-19 Iron status biomarkers; LIHC trans rs875971 0.545 rs35459055 chr7:65944386 G/A cg26939375 chr7:64535504 NA 0.42 6.63 0.34 1.32e-10 Aortic root size; LIHC cis rs2573652 1.000 rs2581343 chr15:100514418 C/G cg09918751 chr15:100517450 ADAMTS17 -0.84 -15.54 -0.64 1.39e-41 Height; LIHC cis rs8014204 0.935 rs2300596 chr14:75353855 C/T cg08847533 chr14:75593920 NEK9 0.38 6.42 0.33 4.69e-10 Caffeine consumption; LIHC cis rs317689 0.581 rs160829 chr12:69769538 G/C cg14784868 chr12:69753453 YEATS4 0.85 16.19 0.66 3.49e-44 Response to diuretic therapy; LIHC cis rs644799 0.930 rs631099 chr11:95563482 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18802567 chr5:171433913 FBXW11 0.54 7.19 0.36 4.06e-12 Lung function (FEV1/FVC); LIHC cis rs4908768 0.539 rs11121205 chr1:8658085 G/A cg20416874 chr1:8611966 RERE -0.61 -11.1 -0.51 1.22e-24 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs875971 1.000 rs12533997 chr7:65965377 A/G cg10756647 chr7:56101905 PSPH 0.44 6.46 0.33 3.59e-10 Aortic root size; LIHC cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg00149659 chr3:10157352 C3orf10 0.75 7.52 0.38 4.99e-13 Alzheimer's disease; LIHC cis rs80282103 0.618 rs11250264 chr10:1151723 A/C cg08668510 chr10:1095578 IDI1 0.61 6.03 0.31 4.29e-9 Glomerular filtration rate (creatinine); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04967530 chr3:99979613 TBC1D23 0.46 7.2 0.36 3.76e-12 Cognitive function; LIHC cis rs13118159 0.778 rs12650998 chr4:1338832 T/C cg13395646 chr4:1353034 KIAA1530 -0.6 -8.29 -0.41 2.7e-15 Longevity; LIHC cis rs11758351 0.660 rs16891443 chr6:26221937 A/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14014604 chr2:175351471 GPR155 -0.45 -6.33 -0.32 7.68e-10 Pancreatic cancer; LIHC cis rs35883536 1.000 rs3904672 chr1:101136651 C/T cg14515779 chr1:101123966 NA -0.7 -14.1 -0.61 6.72e-36 Monocyte count; LIHC cis rs921968 0.541 rs664514 chr2:219329819 A/G cg02985541 chr2:219472218 PLCD4 0.44 7.26 0.37 2.69e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs11048434 0.698 rs7300767 chr12:9123477 T/G cg04155231 chr12:9217510 LOC144571 0.31 5.94 0.31 7.09e-9 Sjögren's syndrome; LIHC cis rs17152411 0.625 rs4962713 chr10:126654536 A/T cg07906193 chr10:126599966 NA -0.31 -6.16 -0.32 2.02e-9 Height; LIHC cis rs12644436 0.526 rs10032322 chr4:88771325 T/G cg06891869 chr4:88767617 MEPE -0.49 -7.75 -0.39 1.05e-13 HIV-1 viral setpoint; LIHC cis rs926392 0.692 rs6028259 chr20:37696977 T/A cg16355469 chr20:37678765 NA 0.48 7.1 0.36 7.06e-12 Dialysis-related mortality; LIHC cis rs798554 0.797 rs1182184 chr7:2872446 G/A cg04166393 chr7:2884313 GNA12 0.46 6.06 0.31 3.54e-9 Height; LIHC cis rs3820068 0.705 rs4646087 chr1:15822404 A/G cg17385448 chr1:15911702 AGMAT 0.38 6.34 0.32 7.41e-10 Systolic blood pressure; LIHC cis rs7582180 0.715 rs1866198 chr2:100917739 C/A cg14675211 chr2:100938903 LONRF2 0.51 7.72 0.39 1.27e-13 Intelligence (multi-trait analysis); LIHC cis rs2115630 0.846 rs8024538 chr15:85368419 A/T cg12501888 chr15:85177176 SCAND2 -0.52 -7.69 -0.38 1.54e-13 P wave terminal force; LIHC cis rs1983891 1.000 rs4714486 chr6:41542417 C/T cg20194872 chr6:41519635 FOXP4 0.4 6.33 0.32 7.78e-10 Prostate cancer; LIHC cis rs7223966 1.000 rs9912904 chr17:61763534 A/C cg05941027 chr17:61774174 LIMD2 0.33 6.71 0.34 8.24e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1475911 0.656 rs9980065 chr21:43528072 G/A cg19766460 chr21:43528205 UMODL1;C21orf128 1.31 20.39 0.74 4.64e-61 IgG glycosylation; LIHC cis rs600806 0.778 rs891380 chr1:110003286 T/G cg10127483 chr1:110009974 SYPL2 0.49 6.04 0.31 3.93e-9 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg05564831 chr3:52568323 NT5DC2 0.38 6.05 0.31 3.78e-9 Bipolar disorder; LIHC trans rs875971 0.502 rs6460311 chr7:66111873 C/T cg26939375 chr7:64535504 NA -0.4 -6.15 -0.32 2.2e-9 Aortic root size; LIHC cis rs9818758 0.607 rs9880088 chr3:49178990 G/A cg00383909 chr3:49044727 WDR6 0.79 6.82 0.35 4.05e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs4808199 0.895 rs2163805 chr19:19575945 G/A cg03709012 chr19:19516395 GATAD2A 1.09 19.63 0.73 5.64e-58 Nonalcoholic fatty liver disease; LIHC cis rs1552244 0.816 rs13076197 chr3:10019773 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs3617 0.539 rs12629687 chr3:52950659 T/C cg18404041 chr3:52824283 ITIH1 0.38 5.77 0.3 1.82e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs7927592 0.871 rs11228284 chr11:68322767 A/T cg16797656 chr11:68205561 LRP5 0.51 8.04 0.4 1.47e-14 Total body bone mineral density; LIHC cis rs9911578 1.000 rs9807057 chr17:56889952 A/C cg05425664 chr17:57184151 TRIM37 -0.58 -8.69 -0.43 1.55e-16 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg03517284 chr6:25882590 NA 0.56 7.6 0.38 2.83e-13 Blood metabolite levels; LIHC cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg11764359 chr7:65958608 NA 0.68 9.24 0.45 2.77e-18 Aortic root size; LIHC cis rs34779708 0.966 rs1545757 chr10:35445588 A/T cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg24209194 chr3:40518798 ZNF619 -0.63 -9.32 -0.45 1.49e-18 Renal cell carcinoma; LIHC cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg02359409 chr6:42947317 PEX6 -0.43 -5.75 -0.3 1.99e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2153535 0.580 rs1577466 chr6:8444192 T/C cg21535247 chr6:8435926 SLC35B3 0.61 7.89 0.39 4.23e-14 Motion sickness; LIHC cis rs172166 0.611 rs203882 chr6:28078502 G/A cg16479474 chr6:28041457 NA 0.39 6.52 0.33 2.57e-10 Cardiac Troponin-T levels; LIHC cis rs9911578 0.935 rs9893351 chr17:57023326 G/A cg12560992 chr17:57184187 TRIM37 0.9 15.98 0.65 2.44e-43 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg07061783 chr6:25882402 NA -0.44 -6.19 -0.32 1.74e-9 Blood metabolite levels; LIHC cis rs12611088 0.515 rs2599454 chr19:44025201 T/C cg13740135 chr19:44006432 PHLDB3 -0.41 -6.08 -0.31 3.16e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs9916302 0.904 rs2024073 chr17:37471330 T/G cg00129232 chr17:37814104 STARD3 0.39 6.32 0.32 8.29e-10 Glomerular filtration rate (creatinine); LIHC cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.32 -5.82 -0.3 1.33e-8 Calcium levels; LIHC trans rs875971 0.660 rs10272357 chr7:66063074 G/A cg26939375 chr7:64535504 NA -0.43 -6.93 -0.35 2.05e-11 Aortic root size; LIHC trans rs75804782 0.521 rs113497020 chr2:239370813 C/T cg01134436 chr17:81009848 B3GNTL1 0.87 7.21 0.36 3.66e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs8017423 0.967 rs2277516 chr14:90722824 G/C cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.18e-41 Mortality in heart failure; LIHC cis rs7044106 0.887 rs1359328 chr9:123370822 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 5.96 0.31 6.15e-9 Hip circumference adjusted for BMI; LIHC cis rs2717559 0.522 rs10956987 chr8:143886613 T/C cg06565975 chr8:143823917 SLURP1 -0.37 -6.34 -0.32 7.38e-10 Urinary tract infection frequency; LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg12016809 chr21:47604291 C21orf56 0.47 7.36 0.37 1.39e-12 Testicular germ cell tumor; LIHC cis rs2576037 0.562 rs9959877 chr18:44522293 T/A cg19077165 chr18:44547161 KATNAL2 -0.48 -7.14 -0.36 5.53e-12 Personality dimensions; LIHC cis rs116095464 0.558 rs7730700 chr5:264713 G/A cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs2839186 0.967 rs4819222 chr21:47707778 G/A cg13126279 chr21:47581558 C21orf56 -0.38 -5.77 -0.3 1.75e-8 Testicular germ cell tumor; LIHC cis rs2404602 0.647 rs11072625 chr15:77084984 A/G cg03037974 chr15:76606532 NA 0.58 9.62 0.46 1.55e-19 Blood metabolite levels; LIHC cis rs2243480 0.901 rs13237344 chr7:66022256 T/A cg18252515 chr7:66147081 NA -1.33 -18.17 -0.7 3.94e-52 Diabetic kidney disease; LIHC cis rs6840360 0.571 rs62327268 chr4:152522326 T/A cg22705602 chr4:152727874 NA -0.32 -6.22 -0.32 1.43e-9 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.720 rs230647 chr21:44919654 C/T cg21573476 chr21:45109991 RRP1B 0.56 9.6 0.46 1.72e-19 Mean corpuscular volume; LIHC cis rs9814567 1.000 rs7426847 chr3:134267519 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs35110281 0.807 rs1598206 chr21:45058776 A/G cg21573476 chr21:45109991 RRP1B -0.53 -9.96 -0.47 1.08e-20 Mean corpuscular volume; LIHC cis rs26868 0.766 rs30995 chr16:2248017 C/T cg02248941 chr16:2239361 CASKIN1 -0.36 -7.07 -0.36 8.67e-12 Height; LIHC cis rs7572733 0.534 rs1401092 chr2:198792320 C/A cg10820045 chr2:198174542 NA -0.48 -7.22 -0.36 3.31e-12 Dermatomyositis; LIHC cis rs1577917 0.687 rs1470531 chr6:86507369 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -7.92 -0.39 3.43e-14 Response to antipsychotic treatment; LIHC cis rs7412746 0.566 rs2864871 chr1:150766964 T/C cg17724175 chr1:150552817 MCL1 0.48 9.37 0.45 9.9e-19 Melanoma; LIHC cis rs16854884 0.657 rs1867609 chr3:143752916 A/G cg06585982 chr3:143692056 C3orf58 0.55 7.21 0.36 3.58e-12 Economic and political preferences (feminism/equality); LIHC cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.16 17.97 0.7 2.69e-51 Gut microbiome composition (summer); LIHC cis rs903552 0.932 rs2172851 chr15:102012626 C/T cg06707286 chr15:102010195 PCSK6 -0.51 -7.21 -0.36 3.7e-12 Diabetic kidney disease; LIHC cis rs6748734 1.000 rs4675863 chr2:241830763 A/T cg20140201 chr2:241835670 C2orf54 -0.47 -6.45 -0.33 3.9e-10 Urinary metabolites; LIHC cis rs5769707 0.616 rs135869 chr22:50008366 T/C cg07959070 chr22:50026188 C22orf34 -0.33 -8.26 -0.41 3.3e-15 Monocyte count;Monocyte percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13494334 chr14:75593888 NEK9 0.48 6.64 0.34 1.26e-10 Lung function (FEV1/FVC); LIHC cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs1577917 1.000 rs12190604 chr6:86716215 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.63 -0.34 1.3e-10 Response to antipsychotic treatment; LIHC cis rs9457247 0.602 rs9459854 chr6:167465882 C/T cg12798992 chr6:167411361 FGFR1OP 0.45 6.75 0.34 6.53e-11 Crohn's disease; LIHC cis rs2549003 0.674 rs960757 chr5:131826310 G/A cg21138405 chr5:131827807 IRF1 0.38 9.69 0.46 8.57e-20 Asthma (sex interaction); LIHC cis rs7089973 0.624 rs17586888 chr10:116598121 T/C cg23260525 chr10:116636907 FAM160B1 0.35 7.05 0.36 1.02e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs35883536 0.647 rs11166485 chr1:101048805 G/C cg14515779 chr1:101123966 NA 0.49 6.75 0.34 6.22e-11 Monocyte count; LIHC cis rs9457247 1.000 rs422562 chr6:167406318 A/G cg23791538 chr6:167370224 RNASET2 -0.65 -10.6 -0.5 7.04e-23 Crohn's disease; LIHC cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.5 0.46 3.76e-19 Bipolar disorder; LIHC cis rs2795502 0.882 rs2744091 chr10:43339441 A/G cg20628663 chr10:43360327 NA -0.47 -7.23 -0.36 3.18e-12 Blood protein levels; LIHC cis rs1008375 1.000 rs3933453 chr4:17636319 A/C cg02297831 chr4:17616191 MED28 0.5 7.73 0.39 1.23e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6570726 0.516 rs10484700 chr6:145728933 C/T cg23711669 chr6:146136114 FBXO30 0.39 6.65 0.34 1.19e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs60871478 0.786 rs55899111 chr7:827843 C/G cg05535760 chr7:792225 HEATR2 -0.96 -13.24 -0.58 1.38e-32 Cerebrospinal P-tau181p levels; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17687970 chr8:22462467 KIAA1967 -0.42 -6.62 -0.34 1.41e-10 Alopecia areata; LIHC cis rs7715806 0.500 rs72633986 chr5:75006449 T/A cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6714710 0.580 rs57681139 chr2:98454473 C/T cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC trans rs4566357 0.615 rs2396445 chr2:227917726 C/G cg16088116 chr21:44841560 SIK1 -0.42 -6.34 -0.32 7.23e-10 Coronary artery disease; LIHC trans rs2506155 0.566 rs56291819 chr10:33529055 A/C cg03349118 chr8:59572480 NSMAF -0.58 -6.11 -0.31 2.75e-9 Migraine; LIHC cis rs526231 0.781 rs2569015 chr5:102608847 A/G cg05225461 chr5:102596755 C5orf30 0.37 5.75 0.3 1.98e-8 Primary biliary cholangitis; LIHC cis rs9549367 0.789 rs12584981 chr13:113881185 T/C cg00898013 chr13:113819073 PROZ -0.43 -7.46 -0.37 7.44e-13 Platelet distribution width; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07791762 chr19:17323290 MYO9B -0.46 -7.06 -0.36 9.32e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs2732480 0.577 rs2732448 chr12:48730600 T/C cg21466736 chr12:48725269 NA -0.73 -11.26 -0.52 3.02e-25 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs700651 0.821 rs4850812 chr2:198743655 G/T cg00792783 chr2:198669748 PLCL1 -0.47 -6.85 -0.35 3.5e-11 Intracranial aneurysm; LIHC trans rs916888 0.773 rs199534 chr17:44824213 T/G cg07870213 chr5:140052090 DND1 1.02 10.5 0.49 1.58e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9309473 0.904 rs62149783 chr2:73821384 T/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.52 -0.33 2.59e-10 Metabolite levels; LIHC cis rs3770081 0.793 rs73943946 chr2:86226623 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -8.44 -0.42 8.84e-16 Facial emotion recognition (sad faces); LIHC cis rs10791097 0.739 rs11222358 chr11:130730497 G/A cg09137382 chr11:130731461 NA 0.42 6.31 0.32 8.44e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg11062466 chr8:58055876 NA 0.45 6.11 0.31 2.75e-9 Developmental language disorder (linguistic errors); LIHC cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.6 0.46 1.72e-19 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.816 rs17792434 chr9:111667319 C/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.93 -0.35 2.09e-11 Menarche (age at onset); LIHC cis rs4853012 0.887 rs77148265 chr2:74339519 C/T cg23149560 chr2:74406255 MOBKL1B 0.45 6.29 0.32 9.93e-10 Gestational age at birth (maternal effect); LIHC cis rs72829446 0.530 rs8071847 chr17:7407327 A/G cg02795151 chr17:7402630 POLR2A 0.55 6.39 0.33 5.45e-10 Androgen levels; LIHC cis rs9818758 0.607 rs3923475 chr3:49055788 G/T cg07636037 chr3:49044803 WDR6 -0.84 -8.52 -0.42 5.33e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11764590 0.694 rs10241537 chr7:2083358 A/G cg23043544 chr7:2124092 MAD1L1 -0.42 -6.85 -0.35 3.5e-11 Neuroticism; LIHC cis rs12762955 0.687 rs4880470 chr10:1077480 G/A cg20335179 chr10:1068567 C10orf110;IDI2 0.42 6.37 0.33 6.06e-10 Response to angiotensin II receptor blocker therapy; LIHC cis rs7927592 0.731 rs11228288 chr11:68353550 A/G cg16797656 chr11:68205561 LRP5 0.5 8.83 0.43 5.35e-17 Total body bone mineral density; LIHC cis rs7249142 0.562 rs10418053 chr19:19287164 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.43 -7.09 -0.36 7.78e-12 IgG glycosylation; LIHC cis rs4450131 0.522 rs3781463 chr10:126337190 C/T cg20435097 chr10:126320824 FAM53B 0.68 12.5 0.56 9.02e-30 White blood cell count (basophil); LIHC cis rs6545883 0.894 rs778148 chr2:61606866 G/A cg14146966 chr2:61757674 XPO1 -0.44 -7.39 -0.37 1.1e-12 Tuberculosis; LIHC cis rs6450176 0.909 rs3776721 chr5:53292522 A/G ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.29 -0.64 1.35e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs8022179 0.566 rs959083 chr14:103822687 A/G cg17675199 chr6:35436792 RPL10A 0.35 6.55 0.33 2.17e-10 Monocyte count; LIHC cis rs1707322 0.721 rs10890341 chr1:46147240 C/A cg06784218 chr1:46089804 CCDC17 0.41 7.58 0.38 3.2e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2842992 0.789 rs9365093 chr6:160175819 C/G cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.87 0.43 4.09e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs1707322 1.000 rs4134387 chr1:46395158 A/T cg06784218 chr1:46089804 CCDC17 0.36 6.31 0.32 8.71e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7412746 0.611 rs3768018 chr1:150723747 T/C cg18016565 chr1:150552671 MCL1 0.55 10.48 0.49 1.73e-22 Melanoma; LIHC cis rs10504073 0.609 rs17644494 chr8:50019679 T/C cg00325661 chr8:49890786 NA 0.32 7.23 0.36 3.1e-12 Blood metabolite ratios; LIHC cis rs7833986 0.501 rs72653986 chr8:57035048 T/C cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.61 0.42 2.65e-16 Height; LIHC cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg04317338 chr11:64019027 PLCB3 0.85 10.78 0.5 1.57e-23 Attention deficit hyperactivity disorder; LIHC cis rs7216064 1.000 rs62084246 chr17:65867911 G/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7772486 0.806 rs4075696 chr6:146250947 T/C cg23711669 chr6:146136114 FBXO30 -0.59 -10.44 -0.49 2.56e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg11060661 chr22:24314208 DDT;DDTL 0.67 11.8 0.54 3.5e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg03264133 chr6:25882463 NA 0.54 7.6 0.38 2.97e-13 Blood metabolite levels; LIHC cis rs600806 0.778 rs891380 chr1:110003286 T/G cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.59 -0.38 3.05e-13 Intelligence (multi-trait analysis); LIHC cis rs6076065 0.748 rs999068 chr20:23376483 G/A cg11657817 chr20:23433608 CST11 0.32 6.74 0.34 6.76e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs798554 0.591 rs1182193 chr7:2869240 A/G cg19717773 chr7:2847554 GNA12 -0.42 -7.23 -0.36 3.27e-12 Height; LIHC trans rs4129059 1.000 rs61443257 chr1:214673211 G/A cg21012737 chr14:105393171 PLD4 -0.36 -6.97 -0.35 1.61e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs67311347 0.955 rs11719205 chr3:40417258 G/A cg13409248 chr3:40428643 ENTPD3 0.4 6.65 0.34 1.14e-10 Renal cell carcinoma; LIHC cis rs8114671 0.562 rs7263157 chr20:33459127 G/A cg07148914 chr20:33460835 GGT7 0.65 9.9 0.47 1.8e-20 Height; LIHC cis rs12142240 0.698 rs45449893 chr1:46859024 A/G cg14993813 chr1:46806288 NSUN4 -0.66 -5.97 -0.31 5.89e-9 Menopause (age at onset); LIHC cis rs6840360 0.615 rs58977077 chr4:152470239 T/G cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs2795502 1.000 rs2795503 chr10:43347224 T/A cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs4853012 0.838 rs12619982 chr2:74356022 G/A cg01017244 chr2:74357527 NA 0.66 12.12 0.55 2.28e-28 Gestational age at birth (maternal effect); LIHC cis rs5769707 0.935 rs1109320 chr22:49989106 G/A cg07959070 chr22:50026188 C22orf34 -0.3 -7.7 -0.38 1.44e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg25894440 chr7:65020034 NA -0.55 -6.4 -0.33 5.14e-10 Diabetic kidney disease; LIHC cis rs748404 0.601 rs502157 chr15:43528573 A/C cg27015174 chr15:43622946 ADAL;LCMT2 -0.37 -5.99 -0.31 5.24e-9 Lung cancer; LIHC cis rs1843834 0.539 rs2047135 chr2:225427302 G/C cg22509189 chr2:225307070 NA -0.83 -11.63 -0.53 1.45e-26 IgE levels in asthmatics (D.p. specific); LIHC cis rs7216064 0.817 rs28609796 chr17:65855104 T/A cg12091567 chr17:66097778 LOC651250 -0.67 -9.35 -0.45 1.16e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9633740 1.000 rs7896832 chr10:82257570 T/C cg01528321 chr10:82214614 TSPAN14 0.93 11.58 0.53 2.11e-26 Post bronchodilator FEV1; LIHC cis rs7020830 0.516 rs36047049 chr9:37375472 G/T cg14294708 chr9:37120828 ZCCHC7 0.79 9.75 0.47 5.53e-20 Schizophrenia; LIHC cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg24642844 chr7:1081250 C7orf50 -0.92 -8.96 -0.44 2.13e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1671400 1.000 rs919586 chr8:13174671 A/G cg14651457 chr8:12611650 LONRF1 -0.6 -6.12 -0.31 2.58e-9 Obesity-related traits; LIHC cis rs8017423 0.740 rs8003095 chr14:90680643 A/T cg04374321 chr14:90722782 PSMC1 0.73 14.03 0.6 1.24e-35 Mortality in heart failure; LIHC cis rs9297145 0.678 rs62473051 chr7:98781955 C/T cg05967295 chr7:98741636 SMURF1 0.73 10.41 0.49 3.16e-22 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs7845219 0.544 rs4570121 chr8:95917088 C/T cg13393036 chr8:95962371 TP53INP1 -0.31 -5.89 -0.3 9.33e-9 Type 2 diabetes; LIHC cis rs34375054 0.525 rs7136220 chr12:125602684 T/C cg25124228 chr12:125621409 AACS -0.5 -9.25 -0.45 2.54e-18 Post bronchodilator FEV1/FVC ratio; LIHC cis rs2033711 0.870 rs1051500 chr19:58944402 A/G cg13877915 chr19:58951672 ZNF132 0.59 9.35 0.45 1.15e-18 Uric acid clearance; LIHC cis rs11252926 0.627 rs10751997 chr10:561952 C/T cg09445902 chr10:555545 DIP2C -0.41 -6.42 -0.33 4.62e-10 Psychosis in Alzheimer's disease; LIHC cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg11062466 chr8:58055876 NA 0.52 7.07 0.36 9e-12 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg11062466 chr8:58055876 NA 0.52 9.23 0.45 3e-18 Developmental language disorder (linguistic errors); LIHC cis rs6815814 0.851 rs4274855 chr4:38777471 C/T cg06935464 chr4:38784597 TLR10 0.5 7.76 0.39 1e-13 Breast cancer; LIHC cis rs240764 0.658 rs9498390 chr6:101241438 T/A cg09795085 chr6:101329169 ASCC3 -0.42 -5.86 -0.3 1.09e-8 Neuroticism; LIHC cis rs1348850 0.874 rs13013752 chr2:178456862 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.77 11.71 0.53 7.57e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7546668 1.000 rs4646093 chr1:15821400 G/T cg11706911 chr1:15910989 AGMAT 0.44 6.8 0.35 4.62e-11 Glomerular filtration rate (creatinine); LIHC cis rs9733 0.744 rs12126004 chr1:150889877 T/C cg18016565 chr1:150552671 MCL1 -0.5 -9.44 -0.45 5.92e-19 Tonsillectomy; LIHC cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.08 0.31 3.13e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg07414643 chr4:187882934 NA 0.23 6.05 0.31 3.86e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.06 0.55 3.63e-28 Prudent dietary pattern; LIHC cis rs7909074 1.000 rs7909074 chr10:45395839 G/A cg05187965 chr10:45406764 TMEM72 -0.28 -6.93 -0.35 2.05e-11 Mean corpuscular volume; LIHC cis rs763121 0.853 rs2281019 chr22:39064378 T/A cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs1448094 0.511 rs7967183 chr12:86216845 T/G cg02569458 chr12:86230093 RASSF9 0.45 6.07 0.31 3.43e-9 Major depressive disorder; LIHC cis rs1707322 1.000 rs12124847 chr1:46380850 T/A cg03146154 chr1:46216737 IPP 0.47 7.47 0.37 6.87e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 1.000 rs951560 chr3:40463471 A/G cg18306943 chr3:40428807 ENTPD3 0.33 5.87 0.3 1.01e-8 Renal cell carcinoma; LIHC cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg18230493 chr5:56204884 C5orf35 -0.48 -6.52 -0.33 2.5e-10 Initial pursuit acceleration; LIHC cis rs10744422 1.000 rs3852537 chr12:123361501 T/C cg22842854 chr12:123319900 HIP1R -0.64 -8.28 -0.41 2.76e-15 Schizophrenia; LIHC cis rs2933343 0.729 rs1680786 chr3:128644840 T/C cg25356066 chr3:128598488 ACAD9 0.52 7.21 0.36 3.68e-12 IgG glycosylation; LIHC cis rs11719291 0.833 rs11715835 chr3:48770732 C/T cg00383909 chr3:49044727 WDR6 0.84 7.21 0.36 3.73e-12 Cognitive function; LIHC cis rs11711311 0.824 rs35341324 chr3:113351719 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.62 -0.34 1.41e-10 IgG glycosylation; LIHC cis rs7726839 1.000 rs7726839 chr5:618586 A/G cg09021430 chr5:549028 NA -0.34 -7.74 -0.39 1.16e-13 Obesity-related traits; LIHC cis rs8062405 1.000 rs7498555 chr16:28893571 T/C cg16576597 chr16:28551801 NUPR1 0.36 5.75 0.3 2.01e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2806561 0.765 rs679591 chr1:23499916 T/C cg12483005 chr1:23474871 LUZP1 0.48 7.51 0.38 5.3e-13 Height; LIHC trans rs60843830 1.000 rs79716074 chr2:277003 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.68 9.65 0.46 1.21e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs858239 1.000 rs166663 chr7:23316742 A/C cg18081818 chr7:23246105 NA -0.4 -6.19 -0.32 1.75e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs8077889 1.000 rs59044152 chr17:41888747 A/G cg26893861 chr17:41843967 DUSP3 0.98 10.83 0.51 1.06e-23 Triglycerides; LIHC cis rs3106136 0.510 rs28838299 chr4:95215887 T/G cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.03 -0.44 1.27e-17 Capecitabine sensitivity; LIHC cis rs2204008 0.557 rs11520191 chr12:38197057 T/A cg26384229 chr12:38710491 ALG10B 0.82 10.18 0.48 1.94e-21 Bladder cancer; LIHC cis rs7208859 0.673 rs3816780 chr17:29161358 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 7.84e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1568889 0.838 rs11030206 chr11:28099747 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.66 13.66 0.59 3.28e-34 Bipolar disorder; LIHC trans rs2749592 0.611 rs176888 chr10:38406161 C/A cg17830980 chr10:43048298 ZNF37B -0.42 -7.65 -0.38 2.11e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10911363 0.509 rs10911339 chr1:183442097 C/T cg09173681 chr1:183549694 NCF2 0.56 9.74 0.47 5.93e-20 Systemic lupus erythematosus; LIHC cis rs8017423 0.967 rs2149655 chr14:90707246 T/C cg04374321 chr14:90722782 PSMC1 0.75 14.41 0.61 4.2e-37 Mortality in heart failure; LIHC cis rs2380220 0.935 rs7744491 chr6:95994980 T/G cg04719120 chr6:96025338 MANEA 0.62 6.8 0.35 4.59e-11 Behavioural disinhibition (generation interaction); LIHC cis rs28829049 0.570 rs12060125 chr1:19391108 A/G cg15948567 chr1:19600454 AKR7L 0.29 5.88 0.3 9.68e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs6684514 1.000 rs12130361 chr1:156260301 C/T cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs644799 1.000 rs474252 chr11:95619292 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.89 15.72 0.65 2.79e-42 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs801193 1.000 rs62466793 chr7:66191517 G/A cg14393609 chr7:65229607 NA 0.37 5.71 0.3 2.42e-8 Aortic root size; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg05025164 chr4:1340916 KIAA1530 0.8 12.68 0.57 1.85e-30 Longevity; LIHC cis rs6788895 1.000 rs1879420 chr3:150466564 A/G cg07663535 chr3:150480033 SIAH2 0.55 6.76 0.34 5.97e-11 Breast cancer; LIHC cis rs7772486 0.720 rs6931553 chr6:146112348 T/C cg05347473 chr6:146136440 FBXO30 -0.39 -6.15 -0.32 2.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10484885 0.775 rs72919985 chr6:90534641 A/G cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.69 -0.34 9.39e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9300255 0.596 rs10734901 chr12:123743447 G/A cg00376283 chr12:123451042 ABCB9 0.65 9.87 0.47 2.22e-20 Neutrophil percentage of white cells; LIHC cis rs17685 0.753 rs4728586 chr7:75802869 T/C cg04592579 chr7:75616294 TMEM120A 0.41 7.0 0.35 1.34e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7520050 0.778 rs3014238 chr1:46090214 A/G cg24296786 chr1:45957014 TESK2 0.43 6.5 0.33 2.83e-10 Red blood cell count;Reticulocyte count; LIHC cis rs9640161 0.711 rs60268791 chr7:150023800 G/T cg21361702 chr7:150065534 REPIN1 0.46 6.24 0.32 1.31e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs1395 0.744 rs11126929 chr2:27472027 C/T cg23587288 chr2:27483067 SLC30A3 0.35 6.68 0.34 9.9e-11 Blood metabolite levels; LIHC cis rs10197940 0.624 rs17270233 chr2:152372420 A/G cg19508488 chr2:152266495 RIF1 0.56 7.96 0.4 2.56e-14 Lung cancer; LIHC cis rs1198430 0.929 rs1210852 chr1:23753533 T/C cg13183780 chr1:23809682 ASAP3 -0.53 -7.56 -0.38 3.75e-13 Total cholesterol levels; LIHC trans rs1945213 0.694 rs34828123 chr11:55837868 T/A cg15704280 chr7:45808275 SEPT13 0.59 7.58 0.38 3.25e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs7911264 1.000 rs10882100 chr10:94460687 C/G cg25093409 chr10:94429542 NA 0.34 5.79 0.3 1.64e-8 Inflammatory bowel disease; LIHC cis rs79387448 0.638 rs6741230 chr2:103069631 C/T cg09003973 chr2:102972529 NA 1.09 9.57 0.46 2.29e-19 Gut microbiota (bacterial taxa); LIHC cis rs17125944 0.505 rs75194546 chr14:53212069 A/C cg13660082 chr14:53194042 PSMC6 -0.46 -7.52 -0.38 4.91e-13 Alzheimer's disease (late onset); LIHC cis rs919433 0.783 rs2565155 chr2:198236425 A/G cg10820045 chr2:198174542 NA 0.56 8.88 0.43 3.78e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1670533 1.000 rs7660779 chr4:1075940 A/G cg27284194 chr4:1044797 NA 0.6 8.92 0.43 2.78e-17 Recombination rate (females); LIHC cis rs7552404 0.727 rs6678348 chr1:76332463 C/T cg03433033 chr1:76189801 ACADM 0.56 7.14 0.36 5.62e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11792861 0.619 rs2289480 chr9:111705501 A/C cg05043794 chr9:111880884 C9orf5 -0.23 -5.79 -0.3 1.63e-8 Menarche (age at onset); LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg06656553 chr16:89960601 TCF25 0.45 5.85 0.3 1.13e-8 Skin colour saturation; LIHC trans rs8113308 0.810 rs7259622 chr19:52445737 C/T cg14959425 chr7:20447707 ITGB8 -0.47 -6.1 -0.31 2.87e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs3106136 0.681 rs11097423 chr4:95303161 G/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs77861329 0.920 rs808787 chr3:52203249 G/A cg08692210 chr3:52188851 WDR51A 0.83 7.86 0.39 5.11e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg22907277 chr7:1156413 C7orf50 0.82 7.04 0.36 1.06e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10911232 0.507 rs4422969 chr1:183020762 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.49 0.49 1.7e-22 Hypertriglyceridemia; LIHC cis rs6840360 0.615 rs12647586 chr4:152607568 G/C cg22705602 chr4:152727874 NA -0.33 -6.84 -0.35 3.57e-11 Intelligence (multi-trait analysis); LIHC cis rs6835098 1.000 rs4695826 chr4:174089426 T/G cg27433088 chr4:174089019 GALNT7 0.39 7.22 0.36 3.35e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs763121 0.853 rs926299 chr22:39095698 C/G cg14440974 chr22:39074834 NA -0.37 -6.25 -0.32 1.21e-9 Menopause (age at onset); LIHC cis rs10463316 0.823 rs7700340 chr5:150776320 C/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.71 -0.34 7.92e-11 Metabolite levels (Pyroglutamine); LIHC cis rs3806843 0.966 rs2563266 chr5:140136915 C/A cg19875535 chr5:140030758 IK -0.37 -6.02 -0.31 4.48e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg18357526 chr6:26021779 HIST1H4A 1.04 15.38 0.64 6.07e-41 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.928 rs10732844 chr1:46372688 T/C cg03146154 chr1:46216737 IPP 0.47 7.66 0.38 1.98e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg08280861 chr8:58055591 NA 0.5 6.13 0.31 2.38e-9 Developmental language disorder (linguistic errors); LIHC cis rs8078723 1.000 rs59925331 chr17:38169273 C/G cg17344932 chr17:38183730 MED24;SNORD124 -0.56 -8.94 -0.44 2.44e-17 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs1475911 0.708 rs56185023 chr21:43521538 T/C cg19766460 chr21:43528205 UMODL1;C21orf128 1.1 18.38 0.7 5.95e-53 IgG glycosylation; LIHC cis rs116975820 0.604 rs80285467 chr12:42564793 T/G cg01256987 chr12:42539512 GXYLT1 -0.53 -5.81 -0.3 1.46e-8 PR interval in Tripanosoma cruzi seropositivity; LIHC cis rs9818758 0.607 rs11719220 chr3:49245201 A/G cg06212747 chr3:49208901 KLHDC8B -0.66 -5.74 -0.3 2.1e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6840360 0.615 rs1877188 chr4:152607931 T/C cg22705602 chr4:152727874 NA -0.33 -6.88 -0.35 2.94e-11 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.941 rs60963894 chr2:136539670 T/G cg07169764 chr2:136633963 MCM6 1.04 14.31 0.61 1.02e-36 Corneal structure; LIHC cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg17747265 chr1:1875780 NA -0.59 -11.53 -0.53 3.25e-26 Body mass index; LIHC cis rs6545883 0.929 rs6707830 chr2:61749472 G/A cg15711740 chr2:61764176 XPO1 -0.44 -6.25 -0.32 1.23e-9 Tuberculosis; LIHC cis rs11696739 0.761 rs2254458 chr20:1551485 C/T cg15722679 chr20:1638393 SIRPG -0.41 -7.91 -0.39 3.57e-14 Mean platelet volume; LIHC cis rs11122272 0.525 rs2739517 chr1:231537914 C/A cg06096015 chr1:231504339 EGLN1 0.49 9.06 0.44 1.01e-17 Hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24555065 chr12:6977392 TPI1 0.45 6.41 0.33 4.9e-10 Pancreatic cancer; LIHC cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg20399509 chr21:47717575 C21orf57 0.37 5.84 0.3 1.18e-8 Testicular germ cell tumor; LIHC cis rs611744 0.550 rs57045491 chr8:109279120 A/C cg21045802 chr8:109455806 TTC35 0.6 10.49 0.49 1.6400000000000001e-22 Dupuytren's disease; LIHC cis rs9814567 1.000 rs9850015 chr3:134269541 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6088590 0.930 rs6120723 chr20:33364655 C/T cg24642439 chr20:33292090 TP53INP2 0.78 10.6 0.5 6.72e-23 Coronary artery disease; LIHC trans rs3749237 0.964 rs2352967 chr3:49871641 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.63 9.69 0.46 9.15e-20 Resting heart rate; LIHC trans rs11157436 0.918 rs2178788 chr14:22618870 T/C cg13567813 chr19:50879636 NR1H2 0.42 6.1 0.31 2.82e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs7927592 0.956 rs7104877 chr11:68377602 G/T cg20283391 chr11:68216788 NA 0.52 7.77 0.39 9.08e-14 Total body bone mineral density; LIHC cis rs860295 0.812 rs3820594 chr1:155829511 C/T cg02153340 chr1:155202674 NA -0.34 -6.24 -0.32 1.3e-9 Body mass index; LIHC cis rs35306767 0.903 rs11816064 chr10:931176 A/C cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs611744 0.967 rs650437 chr8:109210927 T/G cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs6728642 0.901 rs10179966 chr2:97845100 C/T cg26665480 chr2:98280029 ACTR1B -0.63 -6.02 -0.31 4.61e-9 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs17270561 0.723 rs12192635 chr6:25880907 A/T cg16482183 chr6:26056742 HIST1H1C 0.62 7.54 0.38 4.25e-13 Iron status biomarkers; LIHC cis rs58785573 0.570 rs1824652 chr4:38644597 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.5 7.18 0.36 4.41e-12 Lymphocyte percentage of white cells; LIHC cis rs7953508 0.711 rs3825199 chr12:93976954 A/G cg18151635 chr12:93972918 NA -0.49 -7.61 -0.38 2.72e-13 Pubertal anthropometrics; LIHC cis rs4319547 0.915 rs7314638 chr12:122983460 A/G cg23029597 chr12:123009494 RSRC2 -0.54 -7.7 -0.38 1.5e-13 Body mass index; LIHC cis rs9649465 1.000 rs608447 chr7:123395983 A/G cg03229431 chr7:123269106 ASB15 0.37 7.88 0.39 4.55e-14 Migraine; LIHC cis rs477692 1.000 rs538969 chr10:131410608 C/T cg05714579 chr10:131428358 MGMT 0.46 7.58 0.38 3.23e-13 Response to temozolomide; LIHC cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg19774624 chr17:42201019 HDAC5 -0.8 -12.48 -0.56 1.06e-29 Total body bone mineral density; LIHC cis rs929354 0.742 rs886677 chr7:157003782 T/A cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.9e-9 Body mass index; LIHC cis rs6952808 0.771 rs10275045 chr7:1920826 C/T cg21782813 chr7:2030301 MAD1L1 0.43 7.18 0.36 4.37e-12 Bipolar disorder and schizophrenia; LIHC cis rs2380220 0.872 rs2613528 chr6:95939437 C/G cg15832292 chr6:96025679 MANEA -0.58 -6.48 -0.33 3.22e-10 Behavioural disinhibition (generation interaction); LIHC cis rs992157 0.835 rs10932768 chr2:219146199 T/A cg00012203 chr2:219082015 ARPC2 -0.82 -13.04 -0.58 8.12e-32 Colorectal cancer; LIHC cis rs17685 0.784 rs1613890 chr7:75735037 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.76e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7659604 0.605 rs67772833 chr4:122723106 G/A cg19748678 chr4:122722346 EXOSC9 0.43 7.44 0.37 8.04e-13 Type 2 diabetes; LIHC cis rs249954 0.512 rs249870 chr16:23666178 C/A cg09867953 chr16:23706666 ERN2 0.37 6.19 0.32 1.76e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8072100 0.811 rs1912483 chr17:45443494 A/G cg25173405 chr17:45401733 C17orf57 -0.44 -6.02 -0.31 4.41e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1075232 1.000 rs1075232 chr15:31741216 C/A cg01030201 chr15:31746330 NA -0.8 -6.27 -0.32 1.06e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs600806 0.683 rs10857788 chr1:110012289 G/A cg23091122 chr1:110024289 SYPL2 -0.5 -6.69 -0.34 9.06e-11 Intelligence (multi-trait analysis); LIHC cis rs12824058 0.831 rs4759451 chr12:130812739 G/A cg24838063 chr12:130822603 PIWIL1 0.67 9.86 0.47 2.31e-20 Menopause (age at onset); LIHC cis rs7264396 0.563 rs2425117 chr20:34323776 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.74 -0.43 1.08e-16 Total cholesterol levels; LIHC cis rs11864453 0.826 rs2074627 chr16:72136769 C/T cg16558253 chr16:72132732 DHX38 -0.51 -8.06 -0.4 1.25e-14 Fibrinogen levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12620342 chr12:56522011 ESYT1 0.5 6.46 0.33 3.68e-10 Lung function (FEV1/FVC); LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg09177884 chr7:1199841 ZFAND2A -0.46 -6.79 -0.34 5.07e-11 Longevity;Endometriosis; LIHC cis rs8081395 0.741 rs1292056 chr17:57959047 C/T cg13753209 chr17:57696993 CLTC 0.38 5.86 0.3 1.09e-8 White blood cell count; LIHC cis rs1538970 0.884 rs61788261 chr1:45899114 G/A cg05343316 chr1:45956843 TESK2 0.58 8.38 0.41 1.4e-15 Platelet count; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg07677032 chr17:61819896 STRADA 0.44 6.42 0.33 4.45e-10 Prudent dietary pattern; LIHC cis rs6542838 0.641 rs13005124 chr2:99527680 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.44 -7.31 -0.37 1.96e-12 Fear of minor pain; LIHC cis rs1707322 0.721 rs4660883 chr1:46236098 C/T cg06784218 chr1:46089804 CCDC17 0.4 7.18 0.36 4.47e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17685 0.753 rs9691174 chr7:75790405 T/C cg04592579 chr7:75616294 TMEM120A 0.41 7.01 0.35 1.28e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs7648952 chr3:40457038 C/T cg13409248 chr3:40428643 ENTPD3 -0.39 -6.52 -0.33 2.58e-10 Renal cell carcinoma; LIHC cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg00149659 chr3:10157352 C3orf10 0.65 6.97 0.35 1.63e-11 Alzheimer's disease; LIHC cis rs798554 0.757 rs2533882 chr7:2846894 G/T cg19346786 chr7:2764209 NA -0.47 -6.97 -0.35 1.66e-11 Height; LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg12143784 chr7:64541923 NA 0.36 6.3 0.32 9.08e-10 Calcium levels; LIHC cis rs7927771 0.832 rs10838698 chr11:47385923 G/A cg20135002 chr11:47629003 NA 0.5 8.53 0.42 4.72e-16 Subjective well-being; LIHC cis rs2073499 1.000 rs739431 chr3:50255305 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.49 6.02 0.31 4.6e-9 Schizophrenia; LIHC cis rs2421770 0.530 rs7945809 chr11:35369253 G/A cg13971030 chr11:35366721 SLC1A2 -0.44 -7.47 -0.37 6.68e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs9733 0.628 rs11807409 chr1:150683423 C/T cg13175981 chr1:150552382 MCL1 -0.43 -5.95 -0.31 6.69e-9 Tonsillectomy; LIHC cis rs6442522 0.526 rs2168428 chr3:15529304 A/G cg16303742 chr3:15540471 COLQ 0.38 6.0 0.31 5.12e-9 Uric acid levels; LIHC trans rs61931739 0.534 rs10844767 chr12:34152368 C/G cg26384229 chr12:38710491 ALG10B 0.58 7.5 0.38 5.57e-13 Morning vs. evening chronotype; LIHC cis rs7903847 0.596 rs10882934 chr10:99170995 T/G cg08345082 chr10:99160200 RRP12 -0.41 -7.13 -0.36 6.01e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg04632378 chr13:21900426 NA 0.37 6.13 0.31 2.48e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.37 0.41 1.55e-15 Platelet count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20259981 chr8:53301664 ST18 -0.42 -6.19 -0.32 1.72e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7249142 0.549 rs62135499 chr19:19294237 T/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -7.0 -0.35 1.35e-11 IgG glycosylation; LIHC cis rs7173389 0.530 rs6495064 chr15:73682867 C/T cg01796676 chr15:73680284 NA -0.51 -8.29 -0.41 2.64e-15 Resting heart rate; LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.71 -11.94 -0.54 1.08e-27 Prudent dietary pattern; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02111705 chr5:43065244 NA -0.49 -6.28 -0.32 1.01e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7927592 0.913 rs10896346 chr11:68352671 C/T cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.94e-14 Total body bone mineral density; LIHC cis rs8081395 0.899 rs2645477 chr17:57845624 A/C cg02344993 chr17:57696989 CLTC -0.45 -7.21 -0.36 3.7e-12 White blood cell count; LIHC cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.13e-9 Menopause (age at onset); LIHC trans rs1814175 0.588 rs1794144 chr11:49918233 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs7131987 0.845 rs7299861 chr12:29409667 G/A cg21486233 chr12:29375141 FAR2 0.31 6.25 0.32 1.22e-9 QT interval; LIHC cis rs2839186 0.872 rs13052233 chr21:47707284 G/T cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.41e-8 Testicular germ cell tumor; LIHC cis rs35306767 0.903 rs11253485 chr10:919362 C/T cg26597838 chr10:835615 NA 1.18 14.34 0.61 7.88e-37 Eosinophil percentage of granulocytes; LIHC cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg12463550 chr7:65579703 CRCP 0.71 7.44 0.37 8.23e-13 Diabetic kidney disease; LIHC cis rs763014 0.966 rs4984903 chr16:680695 A/G cg00802000 chr16:706648 WDR90 -0.39 -6.31 -0.32 8.55e-10 Height; LIHC cis rs1538970 0.504 rs3790585 chr1:46023356 A/T cg03146154 chr1:46216737 IPP 0.43 5.8 0.3 1.51e-8 Platelet count; LIHC cis rs911119 0.913 rs4815222 chr20:23576964 A/G cg16589663 chr20:23618590 CST3 -0.65 -6.82 -0.35 4.1e-11 Chronic kidney disease; LIHC cis rs11764590 0.715 rs55770986 chr7:2087823 T/C cg23422044 chr7:1970798 MAD1L1 -0.51 -5.81 -0.3 1.41e-8 Neuroticism; LIHC cis rs644799 0.930 rs3802764 chr11:95514599 T/A cg25478527 chr11:95522999 CEP57;FAM76B 0.41 5.78 0.3 1.68e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2997447 0.761 rs17257120 chr1:26450101 A/G cg19633962 chr1:26362018 EXTL1 -0.65 -5.96 -0.31 6.31e-9 QRS complex (12-leadsum); LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.31 0.52 2.11e-25 Prudent dietary pattern; LIHC cis rs11603020 0.950 rs78364821 chr11:57370742 C/T cg19752551 chr11:57585705 CTNND1 -0.47 -5.9 -0.3 8.97e-9 Blood protein levels; LIHC cis rs6912958 0.754 rs1051131 chr6:88221546 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.09 -0.4 1.05e-14 Monocyte percentage of white cells; LIHC cis rs2404602 0.692 rs2304920 chr15:76993867 T/C cg03037974 chr15:76606532 NA 0.74 14.5 0.62 1.74e-37 Blood metabolite levels; LIHC cis rs477692 1.000 rs567700 chr10:131423126 C/T cg19680672 chr10:131412579 MGMT -0.45 -6.86 -0.35 3.33e-11 Response to temozolomide; LIHC cis rs7927771 1.000 rs9909 chr11:47799775 C/G cg20307385 chr11:47447363 PSMC3 -0.44 -5.72 -0.3 2.27e-8 Subjective well-being; LIHC cis rs7903847 0.620 rs61863813 chr10:99112786 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.27 -0.32 1.1e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17906523 chr1:94883536 ABCD3 0.43 6.07 0.31 3.46e-9 Pancreatic cancer; LIHC cis rs250677 0.687 rs40149 chr5:148444275 A/T cg12140854 chr5:148520817 ABLIM3 -0.46 -6.19 -0.32 1.73e-9 Breast cancer; LIHC cis rs4243830 0.850 rs2063806 chr1:6610382 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.85 -10.84 -0.51 1.02e-23 Body mass index; LIHC cis rs250677 0.687 rs36043 chr5:148440983 G/A cg18129178 chr5:148520854 ABLIM3 -0.48 -7.48 -0.38 6.18e-13 Breast cancer; LIHC trans rs7613875 0.620 rs34312088 chr3:50032133 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.43 6.57 0.33 1.84e-10 Body mass index; LIHC cis rs3815700 1.000 rs7260624 chr19:33096562 A/G cg02997394 chr19:33096574 ANKRD27 0.74 9.77 0.47 4.69e-20 Eosinophilic esophagitis; LIHC cis rs875971 0.862 rs9791712 chr7:66105163 C/G cg18876405 chr7:65276391 NA -0.34 -6.17 -0.32 1.97e-9 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26801646 chr10:76970496 VDAC2 0.51 6.87 0.35 3.1e-11 Lung function (FEV1/FVC); LIHC cis rs13064411 0.735 rs6438157 chr3:113207316 G/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg23491599 chr2:155554688 KCNJ3 -0.43 -6.07 -0.31 3.31e-9 Bilirubin levels; LIHC cis rs12702595 0.552 rs10263069 chr7:7269366 C/T cg04827551 chr7:7268805 C1GALT1 0.33 6.13 0.31 2.45e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg02353165 chr6:42928485 GNMT 0.75 11.76 0.54 4.87e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg03735888 chr19:58951602 ZNF132 0.41 7.14 0.36 5.54e-12 Uric acid clearance; LIHC cis rs9522267 0.737 rs7330902 chr13:112227599 C/T cg10483660 chr13:112241077 NA -0.25 -6.33 -0.32 7.83e-10 Hepatitis; LIHC cis rs1144333 1.000 rs60144605 chr1:76359699 A/C cg03433033 chr1:76189801 ACADM 0.55 8.31 0.41 2.21e-15 Attention function in attention deficit hyperactive disorder; LIHC cis rs9457247 1.000 rs385113 chr6:167403971 A/G cg23791538 chr6:167370224 RNASET2 -0.65 -11.02 -0.51 2.23e-24 Crohn's disease; LIHC cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.17 0.32 1.88e-9 Menopause (age at onset); LIHC cis rs2836950 0.545 rs8132424 chr21:40584412 A/T cg06238570 chr21:40685208 BRWD1 0.45 7.37 0.37 1.32e-12 Menarche (age at onset); LIHC cis rs12048904 0.505 rs10493936 chr1:101213335 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.51 -8.18 -0.4 5.67e-15 Multiple sclerosis; LIHC cis rs950169 0.922 rs62021167 chr15:85118051 T/A cg17507749 chr15:85114479 UBE2QP1 0.76 8.67 0.42 1.79e-16 Schizophrenia; LIHC cis rs826838 1.000 rs7975243 chr12:38849220 C/T cg26384229 chr12:38710491 ALG10B 0.98 13.29 0.58 8.46e-33 Heart rate; LIHC trans rs208520 0.690 rs4710564 chr6:66823478 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.74 8.21 0.41 4.68e-15 Exhaled nitric oxide output; LIHC cis rs3008870 0.755 rs2755243 chr1:67482783 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.64 10.73 0.5 2.41e-23 Lymphocyte percentage of white cells; LIHC cis rs7095944 0.585 rs11245357 chr10:126452042 A/G cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.5e-10 Asthma; LIHC cis rs950169 0.920 rs17300048 chr15:84749477 C/T cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg20492807 chr1:225117750 DNAH14 -0.41 -6.11 -0.31 2.75e-9 Immature fraction of reticulocytes; LIHC trans rs3780486 0.813 rs3780488 chr9:33133812 T/C cg04842962 chr6:43655489 MRPS18A 1.08 25.4 0.81 1.05e-80 IgG glycosylation; LIHC cis rs858239 0.600 rs6461692 chr7:23139695 G/C cg23682824 chr7:23144976 KLHL7 0.41 6.15 0.32 2.16e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7582720 1.000 rs116678869 chr2:203819471 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6545883 0.929 rs1900572 chr2:61650715 T/G cg14146966 chr2:61757674 XPO1 -0.45 -7.71 -0.38 1.42e-13 Tuberculosis; LIHC cis rs6137287 0.668 rs6082329 chr20:21100138 G/T cg04219410 chr20:21106687 PLK1S1 -0.33 -5.76 -0.3 1.91e-8 Height; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24636629 chr4:40058917 LOC344967;N4BP2 0.42 6.21 0.32 1.56e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs116095464 0.558 rs9687621 chr5:229194 C/T cg22496380 chr5:211416 CCDC127 -1.11 -10.34 -0.49 5.5e-22 Breast cancer; LIHC cis rs6933660 0.720 rs6913515 chr6:151753470 G/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.52 -7.92 -0.39 3.32e-14 Menarche (age at onset); LIHC cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.81 7.72 0.39 1.28e-13 Platelet count; LIHC cis rs8062405 0.737 rs11861132 chr16:28871860 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2204008 0.777 rs2387813 chr12:38382091 A/C cg26384229 chr12:38710491 ALG10B 0.57 8.0 0.4 2e-14 Bladder cancer; LIHC cis rs1801251 1.000 rs283474 chr2:233654627 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.56 0.53 2.48e-26 Coronary artery disease; LIHC cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.673 rs17826219 chr17:29161845 G/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg03452623 chr4:187889614 NA -0.32 -8.16 -0.4 6.27e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs116248771 0.696 rs16847123 chr3:158416137 C/T cg16708174 chr3:158430962 RARRES1 0.48 6.31 0.32 8.53e-10 diarrhoeal disease at age 2; LIHC trans rs61931739 0.500 rs11053249 chr12:34518834 A/T cg26384229 chr12:38710491 ALG10B 0.8 9.83 0.47 2.96e-20 Morning vs. evening chronotype; LIHC cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg22105103 chr4:187893119 NA 0.34 8.48 0.42 7.07e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs12744310 0.887 rs36015391 chr1:41784805 T/G cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.92e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6748734 1.000 rs4675863 chr2:241830763 A/T cg09990169 chr2:241835740 C2orf54 -0.67 -9.56 -0.46 2.34e-19 Urinary metabolites; LIHC cis rs4268898 0.662 rs17789375 chr2:24502554 G/T cg06627628 chr2:24431161 ITSN2 -0.71 -9.79 -0.47 4.09e-20 Asthma; LIHC trans rs1728785 0.901 rs3087783 chr16:68599668 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.26 0.32 1.13e-9 Ulcerative colitis; LIHC cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg20295408 chr7:1910781 MAD1L1 -0.49 -6.99 -0.35 1.44e-11 Bipolar disorder and schizophrenia; LIHC cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg20295408 chr7:1910781 MAD1L1 -0.5 -7.21 -0.36 3.73e-12 Bipolar disorder and schizophrenia; LIHC cis rs7872515 0.651 rs7863564 chr9:94722509 T/C cg01248375 chr9:94877805 SPTLC1 0.48 6.54 0.33 2.23e-10 Bipolar disorder and schizophrenia; LIHC cis rs8177179 0.967 rs10935085 chr3:133459735 C/T cg16262614 chr3:133464971 TF 0.45 10.24 0.48 1.17e-21 Iron status biomarkers (transferrin levels); LIHC cis rs763014 0.966 rs4984903 chr16:680695 A/G cg09263875 chr16:632152 PIGQ 0.6 10.32 0.49 6.21e-22 Height; LIHC cis rs7309 0.935 rs10930013 chr2:162070325 G/A cg21211367 chr2:162094118 NA 0.37 5.73 0.3 2.25e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs2073499 0.872 rs58051625 chr3:50278717 G/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.63 6.5 0.33 2.76e-10 Schizophrenia; LIHC cis rs787274 0.867 rs1361719 chr9:115535576 A/G cg13803584 chr9:115635662 SNX30 -0.56 -6.25 -0.32 1.21e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs79149102 0.579 rs7163390 chr15:75280426 T/C cg15902774 chr15:75289873 SCAMP5 0.39 5.96 0.31 6.22e-9 Lung cancer; LIHC cis rs10508774 1.000 rs11009023 chr10:32954752 C/G cg01819863 chr10:32635814 EPC1 0.64 5.95 0.31 6.81e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.13 0.55 2.03e-28 Height; LIHC cis rs523522 0.962 rs10774549 chr12:120891172 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.5 0.53 4.13e-26 High light scatter reticulocyte count; LIHC cis rs3020736 0.500 rs6002618 chr22:42507859 G/C cg04733989 chr22:42467013 NAGA -0.64 -9.18 -0.44 4.09e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.679 rs12679941 chr8:58051812 G/T cg20607798 chr8:58055168 NA 0.46 6.37 0.33 6.2e-10 Developmental language disorder (linguistic errors); LIHC cis rs1499280 1.000 rs1991004 chr5:52106866 C/T cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs7512552 0.839 rs1627235 chr1:150358858 C/T cg15654264 chr1:150340011 RPRD2 0.7 11.51 0.53 3.93e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs743757 1.000 rs2236954 chr3:50425177 C/A cg08207895 chr3:50388901 TUSC4;CYB561D2 0.5 7.84 0.39 5.89e-14 Diastolic blood pressure; LIHC trans rs634534 0.591 rs688862 chr11:65733393 A/G cg17712092 chr4:129076599 LARP1B 0.64 9.67 0.46 1.04e-19 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs72634258 0.945 rs12753070 chr1:8114319 C/G cg00042356 chr1:8021962 PARK7 0.91 8.81 0.43 6.36e-17 Inflammatory bowel disease; LIHC cis rs7208859 0.673 rs73277964 chr17:29179201 A/T cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 0.862 rs10256544 chr7:65675128 A/G cg18876405 chr7:65276391 NA 0.34 5.96 0.31 6.31e-9 Aortic root size; LIHC cis rs2526882 0.550 rs10150408 chr14:71563661 G/A cg15816911 chr14:71606274 NA 0.42 6.73 0.34 7.31e-11 Schizophrenia; LIHC cis rs5417 0.662 rs8067500 chr17:7172631 A/G cg14660024 chr17:7154518 C17orf81;DULLARD -0.53 -9.41 -0.45 7.59e-19 Diastolic blood pressure; LIHC cis rs858239 0.539 rs10270695 chr7:23188988 C/T cg23682824 chr7:23144976 KLHL7 -0.42 -6.31 -0.32 8.57e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.74 0.34 6.69e-11 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14138432 chr3:196295511 WDR53;FBXO45 -0.42 -6.19 -0.32 1.71e-9 Pancreatic cancer; LIHC cis rs2243480 0.522 rs778717 chr7:65848151 G/C cg05590025 chr7:65112418 INTS4L2 -0.6 -6.0 -0.31 4.89e-9 Diabetic kidney disease; LIHC cis rs12295403 0.691 rs11607934 chr11:18689168 C/T cg09887367 chr11:18690185 NA -0.4 -5.76 -0.3 1.85e-8 Ovarian reserve; LIHC trans rs11039798 0.660 rs717897 chr11:48375604 A/G cg15704280 chr7:45808275 SEPT13 -0.59 -6.5 -0.33 2.88e-10 Axial length; LIHC cis rs2033711 0.870 rs7409473 chr19:58939165 A/G cg26874164 chr19:58962979 ZNF324B 0.43 6.01 0.31 4.72e-9 Uric acid clearance; LIHC cis rs9910055 0.550 rs113844752 chr17:42297631 C/A cg09913183 chr17:42254507 C17orf65;ASB16 0.55 8.15 0.4 6.93e-15 Total body bone mineral density; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01198024 chr21:33672713 MRAP -0.5 -8.16 -0.4 6.4e-15 Calcium levels; LIHC cis rs7927771 0.524 rs12226431 chr11:47805856 G/A cg20307385 chr11:47447363 PSMC3 0.75 11.22 0.52 4.26e-25 Subjective well-being; LIHC cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.21 0.52 4.8e-25 Colorectal cancer; LIHC cis rs921968 0.643 rs4674320 chr2:219510768 A/G cg02985541 chr2:219472218 PLCD4 0.43 7.89 0.39 4.1e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs546131 0.642 rs2956073 chr11:34842883 C/T cg06937548 chr11:34938143 PDHX;APIP 0.56 7.2 0.36 3.82e-12 Lung disease severity in cystic fibrosis; LIHC cis rs8180040 0.726 rs4682837 chr3:46999707 C/T cg16586182 chr3:47516702 SCAP -0.45 -8.06 -0.4 1.31e-14 Colorectal cancer; LIHC cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg02931644 chr1:25747376 RHCE 0.35 7.42 0.37 9.63e-13 Plateletcrit;Mean corpuscular volume; LIHC cis rs1873147 0.569 rs11071710 chr15:63309193 A/G cg12160578 chr15:63334699 TPM1 0.67 8.87 0.43 4.13e-17 Orofacial clefts; LIHC trans rs6897795 1.000 rs72648830 chr5:177608542 C/T cg19598605 chr2:70056955 GMCL1 -0.59 -7.26 -0.37 2.57e-12 Plateletcrit; LIHC cis rs2153535 0.580 rs2152347 chr6:8474281 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC trans rs1005277 0.563 rs2800550 chr10:38482929 T/C cg27523141 chr10:43048294 ZNF37B 0.38 6.34 0.32 7.24e-10 Extrinsic epigenetic age acceleration; LIHC cis rs10791097 0.690 rs12286234 chr11:130730528 T/C cg12179176 chr11:130786555 SNX19 0.73 11.5 0.53 4.27e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12701220 0.655 rs9638973 chr7:1133678 A/G cg00990874 chr7:1149470 C7orf50 -0.68 -9.79 -0.47 4e-20 Bronchopulmonary dysplasia; LIHC cis rs10870270 1.000 rs10870271 chr10:133754807 A/G cg17892150 chr10:133769511 PPP2R2D 0.7 13.34 0.59 5.66e-33 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs3820068 0.603 rs72645887 chr1:15929905 G/C cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs1552244 0.554 rs17050705 chr3:10046398 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs6545883 1.000 rs6545883 chr2:61772257 A/G cg14146966 chr2:61757674 XPO1 0.43 7.27 0.37 2.54e-12 Tuberculosis; LIHC cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.1 -0.48 3.53e-21 Platelet count; LIHC cis rs6754311 0.773 rs309125 chr2:136643555 C/T cg15123519 chr2:136567270 LCT -0.42 -8.48 -0.42 6.7e-16 Mosquito bite size; LIHC cis rs919433 0.963 rs1429417 chr2:198158171 T/G cg10820045 chr2:198174542 NA -0.59 -9.82 -0.47 3.19e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10464366 0.571 rs13233049 chr7:39187536 C/T cg15212455 chr7:39170539 POU6F2 0.47 8.45 0.42 8.36e-16 IgG glycosylation; LIHC cis rs7582720 0.943 rs72926798 chr2:203827675 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs798554 1.000 rs798545 chr7:2762386 C/T cg04166393 chr7:2884313 GNA12 0.41 5.72 0.3 2.3e-8 Height; LIHC cis rs9486719 1.000 rs13202675 chr6:97028427 C/T cg06623918 chr6:96969491 KIAA0776 -0.71 -7.25 -0.36 2.82e-12 Migraine;Coronary artery disease; LIHC cis rs876084 0.505 rs35529075 chr8:121143623 C/G cg06265175 chr8:121136014 COL14A1 0.42 6.58 0.34 1.82e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8044995 0.501 rs73613999 chr16:68390099 C/A cg03983715 chr16:68378420 PRMT7 -0.51 -6.23 -0.32 1.38e-9 Schizophrenia; LIHC cis rs12365397 0.775 rs12795606 chr11:43243792 C/T cg16667275 chr11:43333495 API5 0.41 6.13 0.31 2.36e-9 Migraine; LIHC cis rs9916302 0.904 rs11867312 chr17:37597748 C/T cg07936489 chr17:37558343 FBXL20 -0.84 -13.48 -0.59 1.65e-33 Glomerular filtration rate (creatinine); LIHC cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg06882758 chr19:58662330 ZNF329 0.93 7.02 0.36 1.17e-11 Cholesterol, total; LIHC cis rs921968 0.541 rs3770214 chr2:219508988 C/T cg18887096 chr2:219472410 PLCD4 -0.4 -5.96 -0.31 6.33e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg11663144 chr21:46675770 NA -0.33 -6.03 -0.31 4.34e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1865760 0.929 rs12195653 chr6:25958621 A/G cg03264133 chr6:25882463 NA -0.39 -5.86 -0.3 1.06e-8 Height; LIHC cis rs2153535 0.580 rs1577470 chr6:8462426 G/A cg21535247 chr6:8435926 SLC35B3 0.63 8.15 0.4 6.78e-15 Motion sickness; LIHC cis rs5769707 0.609 rs2007024 chr22:49988815 C/T cg07959070 chr22:50026188 C22orf34 -0.34 -8.39 -0.41 1.25e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs10751667 0.643 rs7396623 chr11:934104 G/A cg10932868 chr11:921992 NA 0.4 7.58 0.38 3.31e-13 Alzheimer's disease (late onset); LIHC cis rs7106204 0.609 rs12788438 chr11:24284068 G/T ch.11.24196551F chr11:24239977 NA 0.67 6.08 0.31 3.21e-9 Response to Homoharringtonine (cytotoxicity); LIHC cis rs875971 0.660 rs10272357 chr7:66063074 G/A cg18876405 chr7:65276391 NA -0.44 -7.75 -0.39 1.04e-13 Aortic root size; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs2224391 0.737 rs36117780 chr6:5262233 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -5.96 -0.31 6.36e-9 Height; LIHC cis rs2204008 0.702 rs35409806 chr12:38319500 G/A cg26384229 chr12:38710491 ALG10B 0.82 9.4 0.45 8.17e-19 Bladder cancer; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg24209194 chr3:40518798 ZNF619 -0.66 -10.12 -0.48 3.1e-21 Renal cell carcinoma; LIHC cis rs7107174 1.000 rs2510039 chr11:77944480 G/A cg02023728 chr11:77925099 USP35 0.48 8.72 0.43 1.26e-16 Testicular germ cell tumor; LIHC trans rs116095464 0.558 rs55664502 chr5:270485 T/C cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs1059312 0.522 rs3825181 chr12:129279264 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -7.65 -0.38 2.02e-13 Systemic lupus erythematosus; LIHC cis rs2933343 0.621 rs789249 chr3:128578453 T/C cg25356066 chr3:128598488 ACAD9 0.55 7.57 0.38 3.47e-13 IgG glycosylation; LIHC cis rs8114671 0.562 rs1013677 chr20:33468793 C/T cg07148914 chr20:33460835 GGT7 0.64 9.86 0.47 2.45e-20 Height; LIHC cis rs2239547 0.523 rs6803486 chr3:53098209 T/A cg11645453 chr3:52864694 ITIH4 0.28 7.01 0.35 1.28e-11 Schizophrenia; LIHC cis rs12142240 0.698 rs3991877 chr1:46853749 C/A cg14993813 chr1:46806288 NSUN4 -0.66 -5.94 -0.31 6.85e-9 Menopause (age at onset); LIHC cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg27170947 chr2:26402098 FAM59B 0.65 8.11 0.4 9.32e-15 Gut microbiome composition (summer); LIHC cis rs6918586 0.658 rs198825 chr6:26122502 A/G cg18357526 chr6:26021779 HIST1H4A -0.59 -9.09 -0.44 7.92e-18 Schizophrenia; LIHC cis rs72949976 0.934 rs13406406 chr2:214034826 C/T cg08319019 chr2:214017104 IKZF2 -0.61 -6.56 -0.33 1.93e-10 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs11122272 0.735 rs2491407 chr1:231518928 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs3736485 0.966 rs4774596 chr15:51910975 C/A cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.56e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1814175 0.935 rs10839317 chr11:49657228 A/C cg15704280 chr7:45808275 SEPT13 -1.01 -21.71 -0.76 2.59e-66 Height; LIHC cis rs7927592 0.731 rs2840367 chr11:68302101 G/A cg20283391 chr11:68216788 NA 0.36 5.79 0.3 1.63e-8 Total body bone mineral density; LIHC cis rs7107174 1.000 rs2450128 chr11:77940075 G/A cg02023728 chr11:77925099 USP35 0.44 8.59 0.42 3.09e-16 Testicular germ cell tumor; LIHC cis rs1348850 0.793 rs13000048 chr2:178337089 C/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.13 0.58 3.61e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1580019 0.587 rs2392069 chr7:32547154 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.16 0.44 4.82e-18 Cognitive ability; LIHC cis rs8017423 0.874 rs2149656 chr14:90707508 A/C cg04374321 chr14:90722782 PSMC1 0.74 14.15 0.61 4.29e-36 Mortality in heart failure; LIHC cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.18 11.45 0.53 6.23e-26 Platelet count; LIHC cis rs11148252 0.574 rs7139495 chr13:53283318 A/G cg02158880 chr13:53174818 NA 0.36 5.76 0.3 1.9e-8 Lewy body disease; LIHC cis rs17826219 0.636 rs12946563 chr17:29103166 C/G cg14067834 chr17:29058358 SUZ12P 0.7 6.86 0.35 3.28e-11 Body mass index; LIHC cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg12437481 chr16:420112 MRPL28 -0.76 -12.59 -0.56 3.92e-30 Bone mineral density (spine);Bone mineral density; LIHC cis rs7918232 0.662 rs10764662 chr10:27300643 T/A cg14442939 chr10:27389572 ANKRD26 0.59 5.96 0.31 6.44e-9 Breast cancer; LIHC cis rs17376456 0.825 rs74825443 chr5:93254973 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC trans rs61931739 0.500 rs11053213 chr12:34466395 G/T cg26384229 chr12:38710491 ALG10B 0.78 9.56 0.46 2.39e-19 Morning vs. evening chronotype; LIHC cis rs986417 1.000 rs1956549 chr14:60928201 G/A cg27398547 chr14:60952738 C14orf39 0.81 9.56 0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs1577917 0.771 rs2842601 chr6:86330133 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.95 -0.4 2.67e-14 Response to antipsychotic treatment; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02740969 chr7:139477893 TBXAS1;HIPK2 0.38 6.1 0.31 2.82e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7131987 0.718 rs7976961 chr12:29463088 C/T cg21522988 chr12:29376872 FAR2 0.25 5.72 0.3 2.28e-8 QT interval; LIHC cis rs4819052 0.851 rs2838849 chr21:46671027 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.33 0.52 1.82e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9916302 0.904 rs2168785 chr17:37407135 C/T cg00129232 chr17:37814104 STARD3 -0.37 -5.88 -0.3 9.97e-9 Glomerular filtration rate (creatinine); LIHC cis rs6442522 0.678 rs2345106 chr3:15509028 A/G cg16303742 chr3:15540471 COLQ 0.47 7.85 0.39 5.45e-14 Uric acid levels; LIHC cis rs741677 0.663 rs405203 chr17:491009 A/G cg15660573 chr17:549704 VPS53 0.51 8.31 0.41 2.23e-15 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg12310025 chr6:25882481 NA -0.62 -8.78 -0.43 8.07e-17 Blood metabolite levels; LIHC cis rs7208859 0.623 rs7212991 chr17:29143749 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 0.929 rs10950041 chr7:65973875 T/C cg11764359 chr7:65958608 NA 0.91 16.83 0.67 1.04e-46 Aortic root size; LIHC cis rs12666575 0.504 rs10226475 chr7:2226162 A/G cg02951883 chr7:2050386 MAD1L1 -0.42 -6.66 -0.34 1.08e-10 Schizophrenia; LIHC cis rs875971 0.862 rs2420174 chr7:65645361 C/T cg18876405 chr7:65276391 NA -0.36 -6.37 -0.33 5.93e-10 Aortic root size; LIHC cis rs35110281 0.641 rs4818858 chr21:45083097 C/T cg21573476 chr21:45109991 RRP1B 0.6 11.33 0.52 1.79e-25 Mean corpuscular volume; LIHC cis rs7119038 0.818 rs4936441 chr11:118725660 C/G cg19308663 chr11:118741387 NA -0.46 -6.01 -0.31 4.8e-9 Sjögren's syndrome; LIHC cis rs17125944 0.686 rs2357947 chr14:53345378 C/T cg00686598 chr14:53173677 PSMC6 -0.71 -7.89 -0.39 4.05e-14 Alzheimer's disease (late onset); LIHC cis rs2832191 1.000 rs2832185 chr21:30483761 C/G cg08807101 chr21:30365312 RNF160 -0.59 -9.11 -0.44 7.32e-18 Dental caries; LIHC cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs7095607 0.606 rs6480311 chr10:69956848 T/C cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.94e-9 Lung function (FVC); LIHC cis rs9549367 0.826 rs35306827 chr13:113869045 G/A cg00898013 chr13:113819073 PROZ -0.42 -7.33 -0.37 1.64e-12 Platelet distribution width; LIHC cis rs10845606 1.000 rs10845609 chr12:12838920 T/A cg09462578 chr12:12878428 APOLD1 -0.76 -10.08 -0.48 4.37e-21 Systemic lupus erythematosus; LIHC cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg23758822 chr17:41437982 NA 0.93 17.54 0.69 1.44e-49 Menopause (age at onset); LIHC cis rs2243480 0.901 rs34807232 chr7:65965133 G/A cg07424592 chr7:64974309 NA 0.78 9.03 0.44 1.23e-17 Diabetic kidney disease; LIHC cis rs2228479 0.850 rs17226428 chr16:89842884 T/A cg03721293 chr16:90014378 DEF8 0.36 5.72 0.3 2.33e-8 Skin colour saturation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23712970 chr14:23540735 ACIN1 0.42 6.11 0.31 2.76e-9 Pancreatic cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg27077143 chr5:68666458 TAF9;RAD17 0.38 6.18 0.32 1.87e-9 Calcium levels; LIHC cis rs62458065 0.713 rs1597560 chr7:32493886 C/G cg06627557 chr7:32535165 LSM5;AVL9 -0.57 -5.95 -0.31 6.68e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs56104184 0.723 rs1058483 chr19:49407660 G/A cg21252483 chr19:49399788 TULP2 -0.98 -11.25 -0.52 3.34e-25 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs919433 0.680 rs788017 chr2:198265173 T/A cg03934865 chr2:198174659 NA 0.54 8.27 0.41 3.03e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs801193 1.000 rs6958520 chr7:66151453 T/C cg00343986 chr7:65444356 GUSB 0.39 5.85 0.3 1.14e-8 Aortic root size; LIHC cis rs9467773 1.000 rs767471 chr6:26557854 C/T cg11502198 chr6:26597334 ABT1 0.45 6.54 0.33 2.24e-10 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg18252515 chr7:66147081 NA 1.3 16.95 0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg21747090 chr2:27597821 SNX17 -0.44 -6.55 -0.33 2.17e-10 Total body bone mineral density; LIHC cis rs9993613 1.000 rs4694504 chr4:73496691 A/G cg15102770 chr4:73434591 ADAMTS3 0.4 6.28 0.32 1.02e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs8067545 0.750 rs4925080 chr17:19991838 T/A cg13482628 chr17:19912719 NA 0.51 8.6 0.42 2.85e-16 Schizophrenia; LIHC cis rs17826219 0.706 rs55764512 chr17:29085758 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.49e-11 Body mass index; LIHC cis rs4654899 0.758 rs12137408 chr1:21282945 A/G cg08539965 chr1:21396338 EIF4G3 0.34 6.15 0.32 2.22e-9 Superior frontal gyrus grey matter volume; LIHC cis rs13108904 0.517 rs13134568 chr4:1334289 G/A cg05665937 chr4:1216051 CTBP1 0.44 5.87 0.3 1.04e-8 Obesity-related traits; LIHC cis rs11112613 0.818 rs73184099 chr12:106018143 A/G cg03607813 chr12:105948248 NA 0.46 7.16 0.36 4.91e-12 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs4665809 0.838 rs2243834 chr2:26357748 A/C cg27170947 chr2:26402098 FAM59B 0.64 8.43 0.41 9.47e-16 Gut microbiome composition (summer); LIHC cis rs35110281 0.776 rs9983763 chr21:44990578 A/G cg01579765 chr21:45077557 HSF2BP 0.36 6.78 0.34 5.36e-11 Mean corpuscular volume; LIHC cis rs5753037 0.803 rs131263 chr22:30133045 C/T cg01021169 chr22:30184971 ASCC2 -0.32 -5.96 -0.31 6.37e-9 Type 1 diabetes; LIHC cis rs1843834 0.539 rs6713629 chr2:225410973 A/T cg12698349 chr2:225449008 CUL3 0.69 10.69 0.5 3.38e-23 IgE levels in asthmatics (D.p. specific); LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs763121 0.815 rs12168758 chr22:38997269 C/G cg06544989 chr22:39130855 UNC84B 0.35 5.91 0.3 8.18e-9 Menopause (age at onset); LIHC cis rs1144333 1.000 rs112401426 chr1:76466103 T/A cg22875332 chr1:76189707 ACADM 0.4 6.15 0.32 2.16e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2580764 0.678 rs2255112 chr2:55200800 T/G cg09592903 chr2:55203963 RTN4 0.76 14.24 0.61 1.82e-36 Mean platelet volume; LIHC cis rs3768617 0.510 rs10911249 chr1:183080690 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.44 0.49 2.42e-22 Fuchs's corneal dystrophy; LIHC trans rs10761482 0.600 rs72807911 chr10:62228288 T/C cg17314160 chr12:110399253 GIT2 0.44 6.41 0.33 4.89e-10 Schizophrenia; LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg11494091 chr17:61959527 GH2 -0.35 -5.87 -0.3 1.04e-8 Height; LIHC cis rs9399137 0.507 rs6904897 chr6:135382980 T/G cg24558204 chr6:135376177 HBS1L 0.62 10.3 0.49 7.66e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC trans rs2243480 1.000 rs1723267 chr7:65473314 G/A cg10756647 chr7:56101905 PSPH 1.08 13.42 0.59 2.9e-33 Diabetic kidney disease; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg11494091 chr17:61959527 GH2 0.43 8.07 0.4 1.25e-14 Prudent dietary pattern; LIHC cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg16434002 chr17:42200994 HDAC5 -0.54 -7.72 -0.39 1.34e-13 Total body bone mineral density; LIHC cis rs35110281 0.715 rs8129601 chr21:45119104 A/G cg04455712 chr21:45112962 RRP1B 0.47 8.29 0.41 2.58e-15 Mean corpuscular volume; LIHC cis rs4319547 0.656 rs10773088 chr12:122828069 A/T cg23029597 chr12:123009494 RSRC2 -0.53 -7.55 -0.38 4.11e-13 Body mass index; LIHC cis rs7503168 0.908 rs9911863 chr17:33939899 G/A cg20932281 chr17:33905541 PEX12 0.56 6.98 0.35 1.54e-11 Plateletcrit; LIHC cis rs559928 0.606 rs1011219 chr11:63973396 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.72 -7.42 -0.37 9.38e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs9790314 1.000 rs9870059 chr3:161017240 T/C cg04691961 chr3:161091175 C3orf57 -0.4 -6.35 -0.32 6.7e-10 Morning vs. evening chronotype; LIHC cis rs4788570 0.667 rs4788557 chr16:71804802 C/T cg06353428 chr16:71660113 MARVELD3 1.32 14.19 0.61 2.88e-36 Intelligence (multi-trait analysis); LIHC cis rs4555082 0.874 rs2816621 chr14:105732762 A/T cg10792982 chr14:105748885 BRF1 0.46 6.13 0.31 2.36e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs778371 0.723 rs4144795 chr2:233562731 C/G cg08000102 chr2:233561755 GIGYF2 0.76 9.26 0.45 2.34e-18 Schizophrenia; LIHC cis rs7772486 0.713 rs79248977 chr6:146319388 C/A cg13319975 chr6:146136371 FBXO30 -0.44 -7.0 -0.35 1.37e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7617773 0.539 rs12486944 chr3:48390016 G/A cg11946769 chr3:48343235 NME6 0.59 7.29 0.37 2.1e-12 Coronary artery disease; LIHC cis rs748404 0.631 rs3809482 chr15:43661802 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.76 0.47 5.33e-20 Lung cancer; LIHC cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg20607798 chr8:58055168 NA 0.48 5.98 0.31 5.72e-9 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.520 rs6743355 chr2:99732360 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.53 0.64 1.5e-41 Chronic sinus infection; LIHC cis rs1008375 0.931 rs10939733 chr4:17570658 T/C cg02297831 chr4:17616191 MED28 0.47 6.89 0.35 2.66e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6502050 0.835 rs6502079 chr17:80124454 T/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs919433 0.617 rs700638 chr2:198588950 A/C cg03934865 chr2:198174659 NA 0.46 6.7 0.34 8.48e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2651899 0.902 rs2742673 chr1:3080019 A/C cg22674798 chr1:3096360 PRDM16 -0.29 -7.16 -0.36 4.95e-12 Migraine; LIHC cis rs11212260 0.655 rs11212243 chr11:107318547 T/C cg25435332 chr11:107328525 CWF19L2 0.82 8.41 0.41 1.13e-15 IgG glycosylation; LIHC cis rs8017423 0.967 rs11159956 chr14:90715890 C/T cg14092571 chr14:90743983 NA 0.39 6.26 0.32 1.13e-9 Mortality in heart failure; LIHC cis rs4975709 0.589 rs1684967 chr5:1863055 G/C cg14773178 chr5:1868261 NA 0.27 7.05 0.36 9.76e-12 Cardiovascular disease risk factors; LIHC cis rs2257205 0.667 rs77326197 chr17:56905618 T/C cg12560992 chr17:57184187 TRIM37 0.67 7.23 0.36 3.24e-12 Pancreatic cancer; LIHC cis rs2067615 0.542 rs7133161 chr12:107139540 A/G cg15890332 chr12:107067104 RFX4 0.27 6.28 0.32 1.03e-9 Heart rate; LIHC cis rs9790314 0.967 rs1382427 chr3:161032576 T/C cg03342759 chr3:160939853 NMD3 -0.7 -8.34 -0.41 1.83e-15 Morning vs. evening chronotype; LIHC trans rs11148252 0.500 rs342768 chr13:53208882 C/T cg18335740 chr13:41363409 SLC25A15 0.52 9.49 0.46 4.15e-19 Lewy body disease; LIHC cis rs9399135 0.935 rs11760000 chr6:135370496 G/A cg24558204 chr6:135376177 HBS1L 0.45 7.25 0.37 2.78e-12 Red blood cell count; LIHC cis rs896854 0.517 rs10112447 chr8:95955701 C/T cg13393036 chr8:95962371 TP53INP1 -0.37 -7.9 -0.39 3.89e-14 Type 2 diabetes; LIHC cis rs858239 0.600 rs1115941 chr7:23137188 C/T cg23682824 chr7:23144976 KLHL7 0.46 6.86 0.35 3.25e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22045829 chr13:60970476 TDRD3 -0.4 -6.2 -0.32 1.59e-9 Cognitive function; LIHC trans rs1005277 0.540 rs116205409 chr10:38478970 G/A cg23533926 chr12:111358616 MYL2 -0.32 -6.12 -0.31 2.61e-9 Extrinsic epigenetic age acceleration; LIHC cis rs11718455 0.883 rs2372579 chr3:44034003 A/T cg08738300 chr3:44038990 NA 0.52 9.06 0.44 1.01e-17 Coronary artery disease; LIHC cis rs1559088 0.847 rs3786933 chr19:33602881 C/T cg17764715 chr19:33622953 WDR88 0.45 6.5 0.33 2.78e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9611565 0.592 rs9611613 chr22:41961831 T/C cg06634786 chr22:41940651 POLR3H -0.61 -6.54 -0.33 2.24e-10 Vitiligo; LIHC cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg05564831 chr3:52568323 NT5DC2 -0.36 -5.79 -0.3 1.59e-8 Bipolar disorder; LIHC cis rs12478296 0.792 rs6738361 chr2:243014257 C/T cg06360820 chr2:242988706 NA -0.94 -12.28 -0.55 5.83e-29 Obesity-related traits; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.32 -0.32 8.17e-10 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20203792 chr4:20701925 PACRGL 0.44 6.43 0.33 4.19e-10 Pancreatic cancer; LIHC cis rs651907 0.557 rs12629954 chr3:101360623 C/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 12.22 0.55 9.73e-29 Colorectal cancer; LIHC cis rs4891159 0.527 rs690593 chr18:74160408 C/G cg24786174 chr18:74118243 ZNF516 0.79 15.22 0.64 2.57e-40 Longevity; LIHC cis rs67311347 1.000 rs6599102 chr3:40468406 G/A cg18306943 chr3:40428807 ENTPD3 0.33 5.86 0.3 1.07e-8 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg13409248 chr3:40428643 ENTPD3 0.49 8.23 0.41 3.95e-15 Renal cell carcinoma; LIHC cis rs9534288 0.783 rs7987385 chr13:46634131 A/G cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs6545883 0.929 rs2694625 chr2:61616055 G/A cg14146966 chr2:61757674 XPO1 -0.43 -7.31 -0.37 1.93e-12 Tuberculosis; LIHC cis rs1144333 0.655 rs12402347 chr1:76447986 C/T cg03433033 chr1:76189801 ACADM 0.54 7.46 0.37 7.27e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs8180040 0.800 rs6768221 chr3:47296899 C/G cg27129171 chr3:47204927 SETD2 -0.56 -9.11 -0.44 6.87e-18 Colorectal cancer; LIHC cis rs2066819 1.000 rs77447765 chr12:56690662 G/A cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs7208859 0.573 rs73267873 chr17:29068457 C/T cg13385521 chr17:29058706 SUZ12P 0.8 8.26 0.41 3.16e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4727027 0.522 rs6956736 chr7:148893472 G/C cg23583168 chr7:148888333 NA -0.8 -9.99 -0.48 8.93e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg06238570 chr21:40685208 BRWD1 0.62 7.51 0.38 5.29e-13 Cognitive function; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16037096 chr14:20881764 TEP1 -0.55 -6.62 -0.34 1.37e-10 Systolic blood pressure; LIHC cis rs4819052 0.851 rs35560973 chr21:46662573 T/C cg22633049 chr21:46681294 NA -0.36 -6.33 -0.32 7.64e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2576037 0.562 rs13381557 chr18:44513371 A/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.17 -0.36 4.75e-12 Personality dimensions; LIHC cis rs6062302 0.522 rs3787107 chr20:62230576 G/A cg06363034 chr20:62225388 GMEB2 -0.45 -7.56 -0.38 3.77e-13 Glioblastoma; LIHC cis rs10489202 0.632 rs12410730 chr1:168069477 T/C cg24449463 chr1:168025552 DCAF6 -0.57 -8.57 -0.42 3.68e-16 Schizophrenia; LIHC cis rs9425766 0.640 rs2295366 chr1:173825692 A/C cg06124660 chr1:173389066 NA -0.3 -5.84 -0.3 1.19e-8 Life satisfaction; LIHC cis rs116095464 0.558 rs61492827 chr5:225774 A/G cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs11229555 0.645 rs7946522 chr11:58197905 G/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg03874509 chr1:107600012 PRMT6 -0.76 -11.93 -0.54 1.18e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs912057 0.671 rs1294428 chr6:6744623 A/G cg06612196 chr6:6737390 NA 0.51 9.77 0.47 4.85e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs36051895 0.632 rs10974979 chr9:5131731 C/A cg02405213 chr9:5042618 JAK2 -0.64 -10.72 -0.5 2.58e-23 Pediatric autoimmune diseases; LIHC cis rs7572733 0.534 rs700687 chr2:198721560 A/T cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs10504073 0.647 rs341807 chr8:50032676 C/T cg00325661 chr8:49890786 NA 0.32 7.28 0.37 2.26e-12 Blood metabolite ratios; LIHC cis rs6912958 0.559 rs242280 chr6:88048714 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.94 0.51 4.23e-24 Monocyte percentage of white cells; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.13 0.55 2e-28 Prudent dietary pattern; LIHC trans rs7246657 0.765 rs7247259 chr19:37851090 T/C cg24637308 chr11:6592297 DNHD1 0.43 6.09 0.31 2.99e-9 Coronary artery calcification; LIHC cis rs6582630 0.537 rs11611326 chr12:38547958 C/A cg26384229 chr12:38710491 ALG10B 0.97 12.69 0.57 1.64e-30 Drug-induced liver injury (flucloxacillin); LIHC cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs875971 0.660 rs801192 chr7:66031952 C/G cg14393609 chr7:65229607 NA -0.37 -5.81 -0.3 1.4e-8 Aortic root size; LIHC cis rs1023500 0.551 rs2301521 chr22:42423110 G/C cg00645731 chr22:42541494 CYP2D7P1 0.44 6.66 0.34 1.11e-10 Schizophrenia; LIHC cis rs9916302 0.904 rs2338797 chr17:37548241 G/A cg07936489 chr17:37558343 FBXL20 0.85 13.75 0.6 1.49e-34 Glomerular filtration rate (creatinine); LIHC cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg20090690 chr10:134436459 INPP5A 0.44 5.8 0.3 1.5e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7191439 0.657 rs3826076 chr16:88780518 C/T cg02389323 chr16:88786976 FAM38A -0.71 -6.71 -0.34 8.15e-11 Plateletcrit; LIHC cis rs2239815 0.545 rs5762855 chr22:29246605 A/T cg15103426 chr22:29168792 CCDC117 0.44 5.87 0.3 1.06e-8 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.65 9.61 0.46 1.59e-19 Lymphocyte counts; LIHC cis rs67311347 0.713 rs4974018 chr3:40307419 G/A cg00656387 chr3:40428638 ENTPD3 0.4 6.43 0.33 4.4e-10 Renal cell carcinoma; LIHC cis rs600806 0.815 rs10858097 chr1:109967324 C/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.19 -0.36 4.04e-12 Intelligence (multi-trait analysis); LIHC cis rs9733 0.596 rs7418501 chr1:150711896 A/T cg17724175 chr1:150552817 MCL1 0.47 9.84 0.47 2.89e-20 Tonsillectomy; LIHC cis rs1005277 0.579 rs2505241 chr10:38442421 T/C cg25427524 chr10:38739819 LOC399744 -0.64 -12.27 -0.55 6.52e-29 Extrinsic epigenetic age acceleration; LIHC cis rs9393692 0.905 rs34916901 chr6:26286149 G/T cg00631329 chr6:26305371 NA -0.43 -7.23 -0.36 3.16e-12 Educational attainment; LIHC cis rs1552244 0.816 rs13076197 chr3:10019773 T/C cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs6594499 0.872 rs13161853 chr5:110446741 C/A cg04022379 chr5:110408740 TSLP 0.49 8.22 0.41 4.36e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7944584 0.632 rs11606683 chr11:47302733 C/T cg20307385 chr11:47447363 PSMC3 0.58 6.51 0.33 2.73e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs798554 0.757 rs1183085 chr7:2875570 G/A cg04166393 chr7:2884313 GNA12 0.45 6.03 0.31 4.22e-9 Height; LIHC cis rs3762637 0.882 rs72958418 chr3:122160373 G/C cg24169773 chr3:122142474 KPNA1 -0.48 -9.53 -0.46 3.12e-19 LDL cholesterol levels; LIHC cis rs4555082 0.874 rs2816626 chr14:105735425 G/A cg13114125 chr14:105738426 BRF1 -0.74 -9.61 -0.46 1.67e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs870825 0.616 rs6552805 chr4:185637894 C/A cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC cis rs1144333 0.655 rs1361487 chr1:76430471 A/C cg10523679 chr1:76189770 ACADM 0.43 5.92 0.3 7.75e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs15676 0.947 rs6478854 chr9:131588888 G/C cg00228799 chr9:131580591 ENDOG -0.46 -7.07 -0.36 8.95e-12 Blood metabolite levels; LIHC cis rs6582630 0.502 rs2387603 chr12:38353389 A/C cg26384229 chr12:38710491 ALG10B 0.57 7.88 0.39 4.37e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs10870270 0.956 rs4131689 chr10:133744328 A/C cg26149184 chr10:133730230 NA -0.46 -7.39 -0.37 1.1e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7772486 0.875 rs10872583 chr6:146396699 G/T cg13319975 chr6:146136371 FBXO30 0.36 5.97 0.31 5.86e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 0.690 rs7651087 chr3:160821929 T/C cg03342759 chr3:160939853 NMD3 -0.72 -10.93 -0.51 4.62e-24 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs8027181 0.839 rs10459647 chr15:73035241 T/C cg25632853 chr15:73088954 NA 0.36 6.05 0.31 3.77e-9 Triglyceride levels; LIHC trans rs1005277 0.579 rs2983343 chr10:38383332 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs7264396 0.943 rs6060448 chr20:34112192 C/G cg04508476 chr20:34239394 CPNE1;RBM12 0.35 6.11 0.31 2.71e-9 Total cholesterol levels; LIHC cis rs7772486 0.846 rs2748499 chr6:146315002 T/C cg23711669 chr6:146136114 FBXO30 0.66 11.51 0.53 3.81e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs10489202 1.000 rs4656564 chr1:167928992 T/C cg24449463 chr1:168025552 DCAF6 -0.53 -6.73 -0.34 7.36e-11 Schizophrenia; LIHC cis rs735396 0.770 rs2464196 chr12:121435427 G/A cg02403541 chr12:121454288 C12orf43 0.51 9.05 0.44 1.09e-17 N-glycan levels; LIHC cis rs6977660 0.619 rs10231972 chr7:19789354 C/G cg07541023 chr7:19748670 TWISTNB 0.4 6.08 0.31 3.19e-9 Thyroid stimulating hormone; LIHC cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg06481639 chr22:41940642 POLR3H -0.58 -6.05 -0.31 3.7e-9 Vitiligo; LIHC cis rs910316 0.934 rs8006587 chr14:75664939 A/G cg11812906 chr14:75593930 NEK9 0.68 13.0 0.58 1.08e-31 Height; LIHC cis rs6430585 0.583 rs6728946 chr2:136635343 C/G cg07169764 chr2:136633963 MCM6 1.35 23.89 0.79 6.73e-75 Corneal structure; LIHC cis rs6762 0.748 rs7936838 chr11:839093 G/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.64 -0.46 1.31e-19 Mean platelet volume; LIHC cis rs1707322 0.686 rs1541131 chr1:46084934 G/A cg06784218 chr1:46089804 CCDC17 -0.43 -7.95 -0.4 2.67e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17711722 0.653 rs2460421 chr7:65491123 A/T cg18876405 chr7:65276391 NA -0.45 -8.0 -0.4 1.92e-14 Calcium levels; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg11070056 chr1:107600091 PRMT6 0.7 12.14 0.55 1.89e-28 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs4718428 0.705 rs12536410 chr7:66254290 G/A cg10756647 chr7:56101905 PSPH 0.62 8.5 0.42 6.09e-16 Corneal structure; LIHC cis rs644148 0.836 rs2571110 chr19:45000712 T/C cg15540054 chr19:45004280 ZNF180 -0.8 -12.07 -0.55 3.62e-28 Personality dimensions; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg20295408 chr7:1910781 MAD1L1 -0.5 -7.12 -0.36 6.27e-12 Bipolar disorder and schizophrenia; LIHC trans rs783540 0.869 rs783521 chr15:83280445 A/G cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.14 -0.32 2.27e-9 Schizophrenia; LIHC cis rs2204008 0.658 rs11495742 chr12:38395688 C/A cg26384229 chr12:38710491 ALG10B 0.84 10.51 0.49 1.45e-22 Bladder cancer; LIHC cis rs2153535 0.580 rs6597327 chr6:8482157 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs3008870 1.000 rs912797 chr1:67413478 A/G cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC cis rs34375054 0.558 rs12578774 chr12:125681761 A/G cg25124228 chr12:125621409 AACS 0.4 6.9 0.35 2.6e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs13161895 1.000 rs248320 chr5:179432096 G/A cg06664874 chr5:179499304 RNF130 0.58 7.13 0.36 5.93e-12 LDL cholesterol; LIHC cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg03806693 chr22:41940476 POLR3H -1.1 -13.36 -0.59 4.74e-33 Vitiligo; LIHC cis rs734999 0.588 rs4648653 chr1:2535895 C/T cg18854424 chr1:2615690 NA 0.32 6.91 0.35 2.31e-11 Ulcerative colitis; LIHC cis rs11864453 0.826 rs2074626 chr16:72139184 C/A cg01557791 chr16:72042693 DHODH -0.53 -8.57 -0.42 3.64e-16 Fibrinogen levels; LIHC cis rs2832191 0.791 rs2832178 chr21:30479858 T/G cg08807101 chr21:30365312 RNF160 -0.63 -10.05 -0.48 5.42e-21 Dental caries; LIHC cis rs8062405 1.000 rs8055982 chr16:28881202 A/C cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7224668 0.564 rs7223939 chr17:79241521 A/G cg08034816 chr17:79219380 SLC38A10 0.39 6.04 0.31 4.01e-9 IgG glycosylation; LIHC cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg09904177 chr6:26538194 HMGN4 0.55 10.74 0.5 2.16e-23 Intelligence (multi-trait analysis); LIHC cis rs11758351 0.517 rs79958315 chr6:26221826 C/T cg16070018 chr6:26224392 HIST1H3E 0.57 7.05 0.36 9.92e-12 Gout;Renal underexcretion gout; LIHC cis rs7927592 0.913 rs11228292 chr11:68379772 C/T cg20283391 chr11:68216788 NA -0.52 -7.73 -0.39 1.18e-13 Total body bone mineral density; LIHC cis rs11822910 0.815 rs11229028 chr11:57193918 G/A cg00522883 chr11:57194120 SLC43A3 0.67 8.38 0.41 1.36e-15 Platelet distribution width; LIHC cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs875971 0.545 rs73142265 chr7:65699497 G/A cg26939375 chr7:64535504 NA 0.4 6.31 0.32 8.67e-10 Aortic root size; LIHC cis rs9640161 0.871 rs56156367 chr7:150047201 A/T cg27494647 chr7:150038898 RARRES2 0.36 6.67 0.34 1.04e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs3806843 1.000 rs2240694 chr5:140183058 G/A cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.21e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13170468 chr11:10531665 NA -0.4 -6.13 -0.31 2.49e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg04546413 chr19:29218101 NA 0.56 9.98 0.47 9.72e-21 Methadone dose in opioid dependence; LIHC cis rs921968 0.608 rs7598056 chr2:219352511 A/C cg02985541 chr2:219472218 PLCD4 0.45 8.65 0.42 2.09e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs651907 0.557 rs11917569 chr3:101355063 G/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.71 11.83 0.54 2.7e-27 Colorectal cancer; LIHC cis rs477692 1.000 rs554792 chr10:131423181 A/G cg05714579 chr10:131428358 MGMT 0.45 7.4 0.37 1.09e-12 Response to temozolomide; LIHC cis rs523522 0.962 rs655530 chr12:121022275 T/C cg12219531 chr12:120966889 COQ5 0.68 13.23 0.58 1.46e-32 High light scatter reticulocyte count; LIHC cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.88 0.3 9.88e-9 Electroencephalogram traits; LIHC cis rs2573652 0.657 rs2573668 chr15:100541776 C/T cg09918751 chr15:100517450 ADAMTS17 0.65 11.54 0.53 3.07e-26 Height; LIHC cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg22105103 chr4:187893119 NA 0.35 8.75 0.43 1.02e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs10411936 1.000 rs873636 chr19:16514771 C/T cg10248733 chr19:16607483 C19orf44;CALR3 0.43 5.94 0.31 7.09e-9 White blood cell count;Multiple sclerosis; LIHC cis rs7116495 0.609 rs10898812 chr11:71698801 G/A cg26138937 chr11:71823887 C11orf51 -1.28 -10.0 -0.48 8.22e-21 Severe influenza A (H1N1) infection; LIHC cis rs644148 0.836 rs2686776 chr19:45000366 T/C cg15540054 chr19:45004280 ZNF180 -0.78 -11.67 -0.53 1.01e-26 Personality dimensions; LIHC trans rs57221529 0.766 rs12521988 chr5:556421 C/T cg25482853 chr8:67687455 SGK3 0.67 6.67 0.34 1.03e-10 Lung disease severity in cystic fibrosis; LIHC cis rs5769707 0.681 rs8137111 chr22:50043750 G/A cg07959070 chr22:50026188 C22orf34 -0.34 -8.4 -0.41 1.18e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7582720 0.943 rs72934550 chr2:203983940 C/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs9921222 0.502 rs28461430 chr16:369562 G/A cg08923669 chr16:420230 MRPL28 -0.45 -5.88 -0.3 9.96e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs9296092 0.538 rs7761464 chr6:33519417 C/A cg13560919 chr6:33536144 NA -0.38 -6.41 -0.33 4.89e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs561341 0.883 rs6505274 chr17:30344581 G/T cg20587970 chr11:113659929 NA -1.01 -10.18 -0.48 1.99e-21 Hip circumference adjusted for BMI; LIHC cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg24675658 chr1:53192096 ZYG11B 0.57 8.9 0.43 3.28e-17 Monocyte count; LIHC cis rs60871478 1.000 rs60871478 chr7:827325 A/G cg05535760 chr7:792225 HEATR2 0.74 10.22 0.48 1.4e-21 Cerebrospinal P-tau181p levels; LIHC cis rs4819052 1.000 rs13047688 chr21:46669290 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 9.57 0.46 2.21e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6964587 0.839 rs12536702 chr7:91471576 G/C cg17063962 chr7:91808500 NA 0.95 17.08 0.68 1.02e-47 Breast cancer; LIHC cis rs6061231 0.958 rs2427304 chr20:60953584 G/A cg06026331 chr20:60912101 LAMA5 0.44 6.13 0.31 2.43e-9 Colorectal cancer; LIHC cis rs2228479 0.702 rs12600151 chr16:89831558 C/T cg04013166 chr16:89971882 TCF25 0.52 6.46 0.33 3.55e-10 Skin colour saturation; LIHC cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg11644478 chr21:40555479 PSMG1 0.77 9.68 0.46 9.51e-20 Cognitive function; LIHC cis rs644799 1.000 rs543530 chr11:95545170 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg13409248 chr3:40428643 ENTPD3 0.5 8.37 0.41 1.47e-15 Renal cell carcinoma; LIHC cis rs9902453 0.845 rs2321331 chr17:28025528 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.81 0.54 3.07e-27 Coffee consumption (cups per day); LIHC cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 9.14 0.44 5.62e-18 Mean platelet volume; LIHC cis rs6933660 0.512 rs13198669 chr6:151799924 A/G cg10883421 chr6:151773342 RMND1;C6orf211 -0.54 -7.64 -0.38 2.18e-13 Menarche (age at onset); LIHC cis rs5769765 0.862 rs9616386 chr22:50313179 G/A cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs7089973 0.604 rs17663387 chr10:116588060 C/G cg03647239 chr10:116582469 FAM160B1 0.48 7.01 0.35 1.31e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9368481 0.729 rs9379948 chr6:26944783 T/G cg12292205 chr6:26970375 C6orf41 0.47 7.95 0.4 2.68e-14 Autism spectrum disorder or schizophrenia; LIHC trans rs4566357 0.615 rs10178098 chr2:227914425 C/T cg16088116 chr21:44841560 SIK1 -0.41 -6.39 -0.33 5.52e-10 Coronary artery disease; LIHC cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg12311346 chr5:56204834 C5orf35 -0.57 -7.52 -0.38 4.82e-13 Initial pursuit acceleration; LIHC cis rs5769765 0.865 rs4824108 chr22:50271428 A/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs3784262 0.757 rs74655564 chr15:58325512 G/C cg12031962 chr15:58353849 ALDH1A2 -0.36 -6.92 -0.35 2.2e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6882046 0.513 rs34318 chr5:88027149 G/A cg22951263 chr5:87985283 NA -0.39 -6.79 -0.34 5.1e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg13409248 chr3:40428643 ENTPD3 0.47 7.74 0.39 1.11e-13 Renal cell carcinoma; LIHC cis rs6582630 0.555 rs6582503 chr12:38557886 A/C cg13010199 chr12:38710504 ALG10B 0.58 6.89 0.35 2.62e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg00656387 chr3:40428638 ENTPD3 0.49 8.25 0.41 3.48e-15 Renal cell carcinoma; LIHC cis rs754466 0.580 rs10430530 chr10:79582812 T/C cg17075019 chr10:79541650 NA -0.79 -12.45 -0.56 1.3e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7212590 0.581 rs57812342 chr17:57827154 A/G cg10252138 chr17:58120427 NA -0.65 -6.31 -0.32 8.87e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.74 13.76 0.6 1.41e-34 Prudent dietary pattern; LIHC cis rs2455799 0.574 rs2455800 chr3:15701589 T/G cg12698662 chr3:15914712 MIR563 -0.36 -6.71 -0.34 7.91e-11 Mean platelet volume; LIHC cis rs1577917 1.000 rs884841 chr6:86680300 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.08 -0.48 4.45e-21 Response to antipsychotic treatment; LIHC cis rs1003719 0.788 rs2835575 chr21:38455936 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.06 0.55 3.76e-28 Eye color traits; LIHC cis rs7726839 0.574 rs11134148 chr5:637107 C/T cg09021430 chr5:549028 NA -0.42 -8.43 -0.41 9.83e-16 Obesity-related traits; LIHC cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg19318889 chr4:1322082 MAEA -0.48 -7.95 -0.4 2.7e-14 Obesity-related traits; LIHC cis rs769267 0.631 rs7252981 chr19:19692579 T/C cg03709012 chr19:19516395 GATAD2A -0.72 -10.06 -0.48 4.91e-21 Tonsillectomy; LIHC cis rs9868809 0.772 rs73078349 chr3:48688114 G/A cg00383909 chr3:49044727 WDR6 0.95 6.71 0.34 8.03e-11 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC trans rs2832077 0.689 rs2832055 chr21:30132382 C/G cg14791747 chr16:20752902 THUMPD1 -0.47 -6.86 -0.35 3.16e-11 Cognitive test performance; LIHC cis rs1577917 1.000 rs1577917 chr6:86691940 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.9 -0.47 1.73e-20 Response to antipsychotic treatment; LIHC cis rs12644436 0.671 rs13107310 chr4:88787350 G/T cg06891869 chr4:88767617 MEPE 0.42 7.6 0.38 2.93e-13 HIV-1 viral setpoint; LIHC cis rs526821 0.553 rs510095 chr11:55289154 T/C cg04317927 chr11:55418816 OR4S2 0.47 8.96 0.44 2.11e-17 Pediatric bone mineral density (spine); LIHC cis rs2404602 0.655 rs3829489 chr15:77223256 A/C cg03037974 chr15:76606532 NA 0.72 13.99 0.6 1.74e-35 Blood metabolite levels; LIHC trans rs11039100 1.000 rs12362071 chr11:5828450 T/C cg11650987 chr12:10280440 CLEC7A 0.4 6.05 0.31 3.89e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7572733 0.534 rs4550664 chr2:198691405 C/T cg03934865 chr2:198174659 NA 0.46 6.59 0.34 1.63e-10 Dermatomyositis; LIHC cis rs904251 0.965 rs62406516 chr6:37439364 C/T cg01843034 chr6:37503916 NA -0.39 -6.53 -0.33 2.36e-10 Cognitive performance; LIHC cis rs2842992 0.830 rs2495279 chr6:160138796 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.25 0.55 7.54e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs2153535 0.580 rs9328483 chr6:8521295 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.22e-26 Motion sickness; LIHC cis rs7772486 0.875 rs9390377 chr6:146386932 G/A cg13319975 chr6:146136371 FBXO30 -0.39 -6.4 -0.33 4.97e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9549367 0.789 rs3764124 chr13:113897320 C/T cg18105134 chr13:113819100 PROZ -0.7 -12.28 -0.55 5.86e-29 Platelet distribution width; LIHC cis rs17401966 0.838 rs4623 chr1:10366692 C/G cg19773385 chr1:10388646 KIF1B -0.41 -7.46 -0.37 7.27e-13 Hepatocellular carcinoma; LIHC cis rs8017423 0.967 rs61231898 chr14:90691696 G/A cg04374321 chr14:90722782 PSMC1 0.73 13.82 0.6 7.8e-35 Mortality in heart failure; LIHC cis rs1048238 0.506 rs1262788 chr1:16215608 G/C cg00529422 chr1:16285251 ZBTB17 0.35 6.8 0.34 4.8e-11 Systolic blood pressure; LIHC trans rs6598955 0.671 rs12129482 chr1:26623641 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.75 -8.24 -0.41 3.64e-15 Obesity-related traits; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg26634121 chr16:88897219 GALNS 0.43 6.72 0.34 7.84e-11 Longevity; LIHC cis rs9303401 0.614 rs3087762 chr17:56568680 C/T cg25039879 chr17:56429692 SUPT4H1 0.74 8.37 0.41 1.49e-15 Cognitive test performance; LIHC cis rs9649465 0.561 rs2429621 chr7:123430316 A/G cg03229431 chr7:123269106 ASB15 0.43 9.16 0.44 4.81e-18 Migraine; LIHC cis rs7577696 0.524 rs805831 chr2:32484228 C/G cg02381751 chr2:32503542 YIPF4 0.45 6.2 0.32 1.66e-9 Inflammatory biomarkers; LIHC cis rs523522 0.962 rs4766969 chr12:120988238 A/G cg12219531 chr12:120966889 COQ5 0.67 13.33 0.58 6.32e-33 High light scatter reticulocyte count; LIHC cis rs2455799 0.613 rs11128762 chr3:15883439 C/T cg12698662 chr3:15914712 MIR563 -0.41 -7.55 -0.38 3.91e-13 Mean platelet volume; LIHC cis rs9980664 1.000 rs9978569 chr21:34737271 C/T cg04842828 chr21:34696676 IFNAR1 0.46 6.15 0.32 2.21e-9 Cognitive decline (age-related); LIHC cis rs4604732 0.603 rs10925051 chr1:247641834 C/T cg02104434 chr1:247694406 LOC148824;OR2C3 0.24 5.9 0.3 8.94e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC trans rs7178375 1.000 rs7178375 chr15:31215935 C/T cg04373760 chr16:53404718 NA 0.6 7.55 0.38 4.11e-13 Hypertriglyceridemia; LIHC cis rs1387259 0.839 rs7486941 chr12:48578631 C/G cg21466736 chr12:48725269 NA 0.61 9.33 0.45 1.38e-18 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs17376456 0.877 rs17374627 chr5:93296306 C/T cg25358565 chr5:93447407 FAM172A 1.02 9.21 0.45 3.38e-18 Diabetic retinopathy; LIHC cis rs2404602 0.716 rs8025134 chr15:76781729 C/T cg23625390 chr15:77176239 SCAPER 0.36 5.92 0.3 7.83e-9 Blood metabolite levels; LIHC cis rs9768139 0.733 rs13225172 chr7:158120334 G/A cg25566285 chr7:158114605 PTPRN2 0.23 6.09 0.31 3e-9 Calcium levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07148452 chr15:90176987 KIF7 -0.44 -6.45 -0.33 3.74e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs78456975 0.943 rs13391932 chr2:1577679 T/C cg01028140 chr2:1542097 TPO -0.46 -5.71 -0.3 2.41e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs754466 0.510 rs55893027 chr10:79588209 C/T cg17075019 chr10:79541650 NA -0.62 -10.93 -0.51 4.72e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1005277 0.522 rs289645 chr10:37943642 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.6 -0.46 1.78e-19 Extrinsic epigenetic age acceleration; LIHC trans rs877282 0.853 rs12779017 chr10:763619 T/C cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs11673344 0.764 rs524802 chr19:37446947 G/A cg27390819 chr19:37464633 NA -0.53 -6.38 -0.33 5.79e-10 Obesity-related traits; LIHC cis rs9611565 0.592 rs4822040 chr22:41963553 C/G cg06634786 chr22:41940651 POLR3H -0.59 -6.38 -0.33 5.91e-10 Vitiligo; LIHC cis rs7119 0.717 rs34981488 chr15:77723403 T/G cg17802220 chr15:77601643 NA -0.41 -7.11 -0.36 7.01e-12 Type 2 diabetes; LIHC trans rs637571 0.676 rs634534 chr11:65665256 A/G cg17712092 chr4:129076599 LARP1B -0.78 -11.95 -0.54 9.65e-28 Eosinophil percentage of white cells; LIHC cis rs7945705 0.747 rs1980428 chr11:9010497 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.49 8.86 0.43 4.6e-17 Hemoglobin concentration; LIHC cis rs74181299 0.533 rs6722972 chr2:65374596 A/T cg05010058 chr2:65284262 CEP68 -0.36 -5.8 -0.3 1.53e-8 Pulse pressure; LIHC cis rs34779708 0.931 rs4934704 chr10:35332164 C/T cg03585969 chr10:35415529 CREM 0.84 12.73 0.57 1.2e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg26338869 chr17:61819248 STRADA 0.56 8.15 0.4 6.75e-15 Prudent dietary pattern; LIHC cis rs12980942 0.872 rs7248164 chr19:41807700 G/A cg25627403 chr19:41769009 HNRNPUL1 0.5 6.26 0.32 1.13e-9 Coronary artery disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08330117 chr8:90770456 RIPK2 0.47 7.36 0.37 1.4e-12 Cognitive function; LIHC cis rs11673344 0.704 rs540451 chr19:37435521 C/T cg27390819 chr19:37464633 NA -0.49 -5.84 -0.3 1.23e-8 Obesity-related traits; LIHC cis rs11122272 0.735 rs2790880 chr1:231534259 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.53 -0.49 1.19e-22 Hemoglobin concentration; LIHC cis rs2279817 0.863 rs12742364 chr1:18013430 T/A cg21791023 chr1:18019539 ARHGEF10L -0.69 -8.38 -0.41 1.42e-15 Neuroticism; LIHC cis rs2749592 0.513 rs1208708 chr10:38085576 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.41 -6.26 -0.32 1.13e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7586673 0.964 rs34444368 chr2:161954217 G/A cg21518248 chr2:162101506 NA 0.4 5.89 0.3 9.46e-9 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.875 rs2814871 chr6:146312274 G/T cg13319975 chr6:146136371 FBXO30 -0.37 -6.11 -0.31 2.77e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1816752 0.719 rs11843470 chr13:24997699 A/C cg22771759 chr13:24902376 NA 0.32 6.59 0.34 1.71e-10 Obesity-related traits; LIHC cis rs3096299 0.967 rs2965935 chr16:89481274 C/T cg02187348 chr16:89574699 SPG7 -0.48 -7.0 -0.35 1.37e-11 Multiple myeloma (IgH translocation); LIHC cis rs6598955 0.543 rs17163720 chr1:26549399 A/G cg04990556 chr1:26633338 UBXN11 -0.76 -11.07 -0.51 1.56e-24 Obesity-related traits; LIHC cis rs1843834 0.858 rs2047136 chr2:225511361 A/T cg22455342 chr2:225449267 CUL3 0.49 6.42 0.33 4.53e-10 IgE levels in asthmatics (D.p. specific); LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.69 9.92 0.47 1.47e-20 Lymphocyte counts; LIHC cis rs796364 0.760 rs56225698 chr2:200910653 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg22800045 chr5:56110881 MAP3K1 0.63 7.55 0.38 4.02e-13 Initial pursuit acceleration; LIHC cis rs739401 0.595 rs6578304 chr11:2998279 A/G cg20651018 chr11:3035856 CARS 0.37 6.4 0.33 5.13e-10 Longevity; LIHC cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.76 -12.02 -0.55 5.27e-28 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7264396 0.563 rs6060570 chr20:34291166 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.52 -0.42 5.17e-16 Total cholesterol levels; LIHC cis rs1816752 0.774 rs7986162 chr13:25000079 C/T cg02811702 chr13:24901961 NA 0.24 6.01 0.31 4.75e-9 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07866137 chr8:67579786 VCPIP1 0.5 7.21 0.36 3.69e-12 Pancreatic cancer; LIHC cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg07424592 chr7:64974309 NA 0.79 9.39 0.45 8.48e-19 Diabetic kidney disease; LIHC cis rs7772486 0.875 rs2180192 chr6:146322284 T/C cg13319975 chr6:146136371 FBXO30 -0.4 -6.54 -0.33 2.22e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4638749 0.677 rs12611470 chr2:108839349 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs1461503 0.934 rs930982 chr11:122834378 C/T cg25161029 chr11:122845972 NA 0.41 6.85 0.35 3.44e-11 Menarche (age at onset); LIHC cis rs4253772 0.591 rs9627324 chr22:46656511 A/G cg09491104 chr22:46646882 C22orf40 -0.71 -8.35 -0.41 1.68e-15 LDL cholesterol;Cholesterol, total; LIHC trans rs637571 0.522 rs550435 chr11:65732651 G/A cg17712092 chr4:129076599 LARP1B 0.73 12.86 0.57 3.67e-31 Eosinophil percentage of white cells; LIHC cis rs858239 0.600 rs6967475 chr7:23128982 C/T cg23682824 chr7:23144976 KLHL7 0.39 5.93 0.31 7.42e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg24693881 chr1:107596107 NA -0.55 -9.72 -0.47 6.99e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2651899 0.934 rs1627080 chr1:3081309 T/C cg22674798 chr1:3096360 PRDM16 0.26 6.36 0.33 6.31e-10 Migraine; LIHC cis rs787274 1.000 rs787292 chr9:115508529 A/G cg13803584 chr9:115635662 SNX30 0.6 6.36 0.33 6.38e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg11062466 chr8:58055876 NA 0.41 5.8 0.3 1.5e-8 Developmental language disorder (linguistic errors); LIHC cis rs17106184 1.000 rs72904749 chr1:51367420 C/T cg07174182 chr1:51127561 FAF1 -0.75 -8.1 -0.4 1.01e-14 Type 2 diabetes; LIHC cis rs7246657 0.943 rs9917081 chr19:37876616 T/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00482020 chr16:25026850 ARHGAP17 0.39 6.1 0.31 2.89e-9 Lung function (FEV1/FVC); LIHC cis rs17106184 1.000 rs72902789 chr1:51293606 G/C cg07174182 chr1:51127561 FAF1 -0.6 -6.39 -0.33 5.43e-10 Type 2 diabetes; LIHC cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.32 0.45 1.52e-18 Bipolar disorder; LIHC cis rs7818688 0.697 rs57890591 chr8:95983130 G/A cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2549003 1.000 rs2549007 chr5:131826875 T/C cg02551604 chr5:131831745 NA 0.46 6.83 0.35 3.78e-11 Asthma (sex interaction); LIHC cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC cis rs2067615 0.542 rs4346064 chr12:107081599 C/A cg15890332 chr12:107067104 RFX4 0.26 6.15 0.32 2.14e-9 Heart rate; LIHC cis rs10426930 0.639 rs1136405 chr19:5062814 T/C cg18473234 chr19:5097819 KDM4B -0.56 -6.76 -0.34 5.94e-11 Monocyte percentage of white cells; LIHC cis rs9549367 0.773 rs9549717 chr13:113908826 A/G cg18105134 chr13:113819100 PROZ -0.58 -10.19 -0.48 1.84e-21 Platelet distribution width; LIHC cis rs6570726 0.935 rs382910 chr6:145865941 G/A cg23711669 chr6:146136114 FBXO30 0.53 9.18 0.44 4.13e-18 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.765 rs1794141 chr11:49914135 G/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs3008870 0.959 rs56707923 chr1:67388016 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.45 0.66 3.47e-45 Lymphocyte percentage of white cells; LIHC cis rs6690583 0.623 rs74761855 chr1:85432947 A/C cg22153463 chr1:85462885 MCOLN2 0.5 5.89 0.3 9.03e-9 Serum sulfate level; LIHC trans rs60843830 0.928 rs2306060 chr2:230912 A/C cg11347411 chr7:150020925 ACTR3C;LRRC61 0.65 9.23 0.45 2.88e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs7618501 0.602 rs2245365 chr3:50097319 C/A cg21467203 chr3:49911342 NA 0.42 7.39 0.37 1.11e-12 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.76 0.3 1.83e-8 Menopause (age at onset); LIHC cis rs2108622 0.727 rs62106158 chr19:15980492 T/G cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg26921586 chr4:493489 ZNF721;PIGG -0.56 -6.27 -0.32 1.1e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs61931739 0.517 rs1843738 chr12:34056935 C/T cg26384229 chr12:38710491 ALG10B 0.51 7.1 0.36 7.35e-12 Morning vs. evening chronotype; LIHC cis rs9814567 1.000 rs9863786 chr3:134247203 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7116495 0.609 rs12275171 chr11:71835373 C/T cg26138937 chr11:71823887 C11orf51 1.32 10.9 0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs8078723 0.674 rs9303284 chr17:38205793 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.53 8.42 0.41 1.07e-15 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15166898 chr19:59008294 NA -0.46 -6.29 -0.32 9.79e-10 Lung function (FEV1/FVC); LIHC cis rs7715806 0.500 rs4703676 chr5:74979866 G/C cg00601450 chr5:74908170 NA 0.59 7.18 0.36 4.27e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1577917 1.000 rs34106666 chr6:86676258 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.55 -0.33 2.08e-10 Response to antipsychotic treatment; LIHC cis rs1789 0.786 rs6414768 chr4:15695363 A/G cg21123203 chr4:15471301 CC2D2A -0.44 -6.86 -0.35 3.28e-11 Blood protein levels; LIHC cis rs7044106 0.791 rs4837793 chr9:123483621 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 8.27 0.41 3e-15 Hip circumference adjusted for BMI; LIHC cis rs10256972 0.616 rs6957733 chr7:1106327 T/G cg23978390 chr7:1156363 C7orf50 0.41 5.78 0.3 1.65e-8 Longevity;Endometriosis; LIHC cis rs3796352 1.000 rs34933390 chr3:53006265 T/G cg04865290 chr3:52927548 TMEM110 -0.51 -5.91 -0.3 8.05e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7089973 0.604 rs17663387 chr10:116588060 C/G cg23260525 chr10:116636907 FAM160B1 0.39 7.8 0.39 7.72e-14 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7833986 0.501 rs2953922 chr8:56977485 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.76 0.43 9.13e-17 Height; LIHC cis rs10751667 0.643 rs7395592 chr11:934094 C/G ch.11.42038R chr11:967971 AP2A2 0.54 9.72 0.47 6.88e-20 Alzheimer's disease (late onset); LIHC cis rs4240897 0.835 rs4845891 chr1:12042506 T/C cg13216073 chr1:12042593 MFN2 0.5 8.03 0.4 1.63e-14 Tuberculosis; LIHC cis rs4819052 0.851 rs2330011 chr21:46658498 G/A cg11663144 chr21:46675770 NA -0.31 -5.8 -0.3 1.52e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6442522 0.678 rs12494919 chr3:15498272 G/A cg16303742 chr3:15540471 COLQ 0.44 7.54 0.38 4.15e-13 Uric acid levels; LIHC cis rs3849570 1.000 rs9826270 chr3:81841869 C/T cg07356753 chr3:81810745 GBE1 -0.62 -10.3 -0.49 7.5e-22 Waist circumference;Body mass index; LIHC cis rs1198430 0.562 rs7546989 chr1:23789698 C/G cg13183780 chr1:23809682 ASAP3 -0.34 -6.08 -0.31 3.29e-9 Total cholesterol levels; LIHC cis rs9640161 0.742 rs2159235 chr7:150017228 T/C cg21361702 chr7:150065534 REPIN1 0.46 6.35 0.32 6.92e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs8141529 0.778 rs5762795 chr22:29182500 C/A cg02153584 chr22:29168773 CCDC117 0.56 9.15 0.44 5.24e-18 Lymphocyte counts; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10765909 chr12:53715428 AAAS 0.39 6.46 0.33 3.55e-10 Calcium levels; LIHC cis rs12586317 0.547 rs45531432 chr14:35484423 C/T cg05294307 chr14:35346193 BAZ1A -0.49 -7.42 -0.37 9.63e-13 Psoriasis; LIHC cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.855 rs12774985 chr10:904245 C/T cg26597838 chr10:835615 NA 1.47 16.88 0.67 6.43e-47 Eosinophil percentage of granulocytes; LIHC cis rs4891159 0.548 rs654754 chr18:74143695 T/C cg24786174 chr18:74118243 ZNF516 0.82 16.39 0.66 5.92e-45 Longevity; LIHC cis rs9486719 1.000 rs4077932 chr6:96905144 C/T cg06623918 chr6:96969491 KIAA0776 -0.71 -7.14 -0.36 5.8e-12 Migraine;Coronary artery disease; LIHC cis rs950169 0.810 rs62029594 chr15:84955252 T/C cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.12e-11 Schizophrenia; LIHC cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg11062466 chr8:58055876 NA 0.54 9.33 0.45 1.4e-18 Developmental language disorder (linguistic errors); LIHC cis rs7534824 0.543 rs61780300 chr1:101403601 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.64 7.49 0.38 6.07e-13 Refractive astigmatism; LIHC cis rs6429082 0.818 rs453315 chr1:235680585 C/T cg26050004 chr1:235667680 B3GALNT2 0.48 7.4 0.37 1.06e-12 Adiposity; LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.39 0.8 7.99e-77 Prudent dietary pattern; LIHC cis rs4474465 0.831 rs7121299 chr11:78189133 G/T cg27205649 chr11:78285834 NARS2 -0.38 -6.0 -0.31 5.02e-9 Alzheimer's disease (survival time); LIHC cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17545146 chr20:62289982 RTEL1 -0.53 -6.1 -0.31 2.9e-9 Systolic blood pressure; LIHC cis rs77633900 0.614 rs2469241 chr15:76873908 A/G cg21673338 chr15:77095150 SCAPER -0.48 -7.11 -0.36 6.97e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs6429082 0.749 rs3819974 chr1:235601958 G/T cg26050004 chr1:235667680 B3GALNT2 -0.46 -6.99 -0.35 1.41e-11 Adiposity; LIHC cis rs1355223 0.902 rs1258468 chr11:34729731 G/A cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.32 -0.32 8.28e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6732160 0.650 rs7560224 chr2:73406182 A/G cg24220031 chr2:73402428 NA -0.28 -6.08 -0.31 3.24e-9 Intelligence (multi-trait analysis); LIHC cis rs2257205 0.667 rs7213035 chr17:56857281 A/G cg12560992 chr17:57184187 TRIM37 0.68 7.44 0.37 8.24e-13 Pancreatic cancer; LIHC cis rs17253792 0.822 rs79618862 chr14:56093971 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs6964587 1.000 rs6964587 chr7:91630620 G/T cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC trans rs2727020 0.729 rs7924782 chr11:49267249 A/G cg15704280 chr7:45808275 SEPT13 -0.89 -16.02 -0.65 1.72e-43 Coronary artery disease; LIHC cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg08219700 chr8:58056026 NA 0.42 5.78 0.3 1.73e-8 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 11.55 0.53 2.76e-26 Platelet count; LIHC cis rs2180341 0.782 rs6569490 chr6:127729615 C/T cg27446573 chr6:127587934 RNF146 0.79 13.09 0.58 5.05e-32 Breast cancer; LIHC cis rs9322817 0.691 rs6929746 chr6:105167548 G/C cg02098413 chr6:105308735 HACE1 -0.4 -7.49 -0.38 5.82e-13 Thyroid stimulating hormone; LIHC cis rs28374715 0.662 rs28493087 chr15:41486504 G/A cg18705301 chr15:41695430 NDUFAF1 -0.88 -9.72 -0.47 7.19e-20 Ulcerative colitis; LIHC cis rs61041384 0.661 rs74240769 chr12:123688228 C/A cg00376283 chr12:123451042 ABCB9 -0.55 -6.14 -0.32 2.28e-9 Schizophrenia; LIHC cis rs2075371 0.611 rs34573600 chr7:134018937 C/T cg20476274 chr7:133979776 SLC35B4 0.47 6.31 0.32 8.75e-10 Mean platelet volume; LIHC cis rs9303401 0.538 rs2240259 chr17:56458129 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.8 10.08 0.48 4.18e-21 Cognitive test performance; LIHC cis rs34115320 1 rs34115320 chr7:148783936 CT/C cg23583168 chr7:148888333 NA -0.67 -8.89 -0.43 3.69e-17 Sum basophil neutrophil counts;Neutrophil count; LIHC cis rs748404 0.723 rs573169 chr15:43550581 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.43 6.64 0.34 1.2e-10 Lung cancer; LIHC cis rs933688 1.000 rs12656350 chr5:90751343 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.31 0.66 1.17e-44 Smoking behavior; LIHC cis rs826838 0.967 rs826876 chr12:39123843 T/C cg26384229 chr12:38710491 ALG10B -0.61 -8.92 -0.43 2.87e-17 Heart rate; LIHC cis rs2070488 0.861 rs2067082 chr3:38438182 C/G cg24069376 chr3:38537580 EXOG 0.37 6.75 0.34 6.3e-11 Electrocardiographic conduction measures; LIHC cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg13393036 chr8:95962371 TP53INP1 -0.39 -8.83 -0.43 5.69e-17 Type 2 diabetes; LIHC cis rs2976388 0.609 rs2717605 chr8:143801015 T/G cg13446199 chr8:143762866 PSCA -0.2 -5.8 -0.3 1.48e-8 Urinary tract infection frequency; LIHC cis rs8180040 0.966 rs11719877 chr3:47425473 C/T cg27129171 chr3:47204927 SETD2 0.56 9.49 0.46 4.12e-19 Colorectal cancer; LIHC cis rs2710642 0.586 rs62180020 chr2:62819915 C/G cg17519650 chr2:63277830 OTX1 0.44 6.92 0.35 2.25e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs9633740 0.578 rs7084416 chr10:82304297 G/A cg01528321 chr10:82214614 TSPAN14 -0.65 -6.97 -0.35 1.59e-11 Post bronchodilator FEV1; LIHC cis rs1552244 0.572 rs7645667 chr3:10157337 C/A cg00149659 chr3:10157352 C3orf10 1.13 9.96 0.47 1.1e-20 Alzheimer's disease; LIHC cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -10.49 -0.49 1.7e-22 Platelet count; LIHC trans rs11098499 0.530 rs114866537 chr4:120258608 A/T cg25214090 chr10:38739885 LOC399744 0.45 7.39 0.37 1.14e-12 Corneal astigmatism; LIHC cis rs9790314 0.631 rs2061804 chr3:161102474 C/A cg03342759 chr3:160939853 NMD3 -0.55 -8.75 -0.43 9.65e-17 Morning vs. evening chronotype; LIHC trans rs9929218 1.000 rs9936621 chr16:68798682 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.76 -0.43 9.39e-17 Colorectal cancer; LIHC cis rs10789491 0.588 rs2099766 chr1:47193987 T/C cg15501359 chr1:47185051 KIAA0494 0.77 9.8 0.47 3.73e-20 Response to hepatitis C treatment; LIHC cis rs7618501 1.000 rs2234391 chr3:49842625 A/G cg21467203 chr3:49911342 NA -0.41 -7.17 -0.36 4.75e-12 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg13126279 chr21:47581558 C21orf56 -0.47 -7.88 -0.39 4.51e-14 Testicular germ cell tumor; LIHC cis rs9911578 0.874 rs302874 chr17:56767996 A/G cg12560992 chr17:57184187 TRIM37 0.96 17.77 0.69 1.61e-50 Intelligence (multi-trait analysis); LIHC cis rs1775715 0.737 rs2778661 chr10:32159191 C/T cg14930904 chr10:32216787 ARHGAP12 0.35 6.09 0.31 2.96e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs7917772 0.536 rs3961456 chr10:104425304 A/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.73 -8.95 -0.44 2.37e-17 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1215050 0.740 rs6854802 chr4:99065480 A/C cg05340658 chr4:99064831 C4orf37 0.4 6.15 0.32 2.22e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs711245 0.748 rs2276671 chr2:36771701 C/A cg09467607 chr2:36825704 FEZ2 0.47 6.87 0.35 2.98e-11 Height; LIHC trans rs877282 0.947 rs12358875 chr10:757531 T/C cg22713356 chr15:30763199 NA 1.42 12.22 0.55 9.43e-29 Uric acid levels; LIHC cis rs1552244 0.554 rs6786636 chr3:10045703 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -8.03 -0.4 1.55e-14 Alzheimer's disease; LIHC cis rs7772486 0.875 rs6914813 chr6:146397798 A/G cg13319975 chr6:146136371 FBXO30 -0.41 -6.54 -0.33 2.23e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs55665837 1.000 rs4412729 chr11:14439000 A/G cg19336497 chr11:14380999 RRAS2 -0.46 -8.4 -0.41 1.24e-15 Vitamin D levels; LIHC cis rs992157 0.560 rs6436047 chr2:219108913 A/C cg20019365 chr2:219134978 PNKD;AAMP 0.75 12.29 0.55 5.11e-29 Colorectal cancer; LIHC cis rs9399135 0.967 rs7763836 chr6:135362378 T/C cg22676075 chr6:135203613 NA 0.41 6.57 0.33 1.87e-10 Red blood cell count; LIHC cis rs6062302 0.545 rs2297430 chr20:62229244 T/C cg06363034 chr20:62225388 GMEB2 -0.44 -7.52 -0.38 4.72e-13 Glioblastoma; LIHC cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg03517284 chr6:25882590 NA 0.89 12.6 0.56 3.55e-30 Blood metabolite levels; LIHC cis rs924607 1.000 rs12523022 chr5:598643 C/T cg24163568 chr5:669837 TPPP -0.41 -8.58 -0.42 3.48e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs35110281 0.686 rs162399 chr21:44950020 G/A cg21573476 chr21:45109991 RRP1B -0.58 -10.54 -0.5 1.15e-22 Mean corpuscular volume; LIHC cis rs2624839 0.704 rs2624833 chr3:50212512 G/T cg21467203 chr3:49911342 NA -0.44 -5.9 -0.3 8.68e-9 Intelligence (multi-trait analysis); LIHC cis rs7914558 0.966 rs10883817 chr10:104755431 C/T cg15744005 chr10:104629667 AS3MT -0.36 -8.01 -0.4 1.78e-14 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1866706 1.000 rs11022517 chr11:12884855 G/A cg25843174 chr11:12811716 TEAD1 0.3 6.31 0.32 8.6e-10 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.531 rs1107351 chr7:2177093 G/A cg04267008 chr7:1944627 MAD1L1 -0.49 -7.58 -0.38 3.21e-13 Bipolar disorder and schizophrenia; LIHC cis rs11674184 0.564 rs746579 chr2:11744694 C/T cg07314298 chr2:11723111 GREB1 -0.44 -7.0 -0.35 1.35e-11 Endometriosis; LIHC cis rs7223966 1.000 rs9908044 chr17:61747032 A/C cg05941027 chr17:61774174 LIMD2 0.3 5.97 0.31 5.91e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg01788221 chr16:89496183 ANKRD11 -0.38 -5.87 -0.3 1.01e-8 Multiple myeloma (IgH translocation); LIHC trans rs1034394 0.775 rs5999351 chr22:34818610 A/T cg02641517 chr3:54169983 CACNA2D3 -0.24 -6.1 -0.31 2.93e-9 Major depressive disorder; LIHC cis rs769267 0.930 rs7254927 chr19:19404786 C/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.14e-9 Tonsillectomy; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.91 0.57 2.45e-31 Prudent dietary pattern; LIHC cis rs5769765 0.955 rs5769767 chr22:50276909 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs1371867 0.846 rs1613453 chr8:101244215 G/T cg06636551 chr8:101224915 SPAG1 0.49 9.33 0.45 1.34e-18 Atrioventricular conduction; LIHC cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg06238570 chr21:40685208 BRWD1 0.59 6.9 0.35 2.48e-11 Cognitive function; LIHC cis rs9517302 0.615 rs9517306 chr13:99097962 T/C cg22223119 chr13:99095684 FARP1 -0.6 -8.62 -0.42 2.45e-16 Obesity-related traits; LIHC cis rs11122272 0.735 rs2486746 chr1:231497324 C/T cg06096015 chr1:231504339 EGLN1 0.52 9.66 0.46 1.12e-19 Hemoglobin concentration; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg18357526 chr6:26021779 HIST1H4A -0.88 -12.36 -0.56 3.02e-29 Intelligence (multi-trait analysis); LIHC cis rs4938303 0.633 rs567209 chr11:116534828 C/T cg13436940 chr11:116064295 NA 0.42 5.72 0.3 2.37e-8 Triglycerides; LIHC cis rs1997103 1.000 rs6954474 chr7:55404847 A/G cg17469321 chr7:55412551 NA 0.48 7.01 0.35 1.26e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2273156 0.636 rs12892552 chr14:35505414 A/G cg16230307 chr14:35515116 FAM177A1 -0.42 -6.06 -0.31 3.67e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC trans rs116095464 0.558 rs6872854 chr5:209038 G/T cg00938859 chr5:1591904 SDHAP3 0.55 6.48 0.33 3.24e-10 Breast cancer; LIHC cis rs72627509 0.951 rs17087335 chr4:57838583 G/T cg26694713 chr4:57773883 REST 0.67 9.36 0.45 1.09e-18 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs67311347 0.822 rs11709089 chr3:40351484 C/T cg00656387 chr3:40428638 ENTPD3 0.38 5.98 0.31 5.69e-9 Renal cell carcinoma; LIHC cis rs9896052 0.514 rs11656576 chr17:73447658 T/C cg25649188 chr17:73499917 CASKIN2 0.47 7.03 0.36 1.11e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs3749237 0.964 rs62260719 chr3:49852419 G/A cg03060546 chr3:49711283 APEH 0.38 5.79 0.3 1.6e-8 Resting heart rate; LIHC cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg08888203 chr3:10149979 C3orf24 0.57 6.49 0.33 3.06e-10 Alzheimer's disease; LIHC cis rs965469 0.947 rs965468 chr20:3381443 C/T cg25506879 chr20:3388711 C20orf194 -0.58 -6.67 -0.34 1.01e-10 IFN-related cytopenia; LIHC cis rs853679 0.517 rs9393893 chr6:28109262 T/C cg16479474 chr6:28041457 NA 0.45 6.34 0.32 7.43e-10 Depression; LIHC cis rs5769765 0.908 rs9616217 chr22:50318946 C/T cg02269571 chr22:50332266 NA -0.67 -9.09 -0.44 7.97e-18 Schizophrenia; LIHC cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg24531977 chr5:56204891 C5orf35 -0.67 -9.62 -0.46 1.54e-19 Initial pursuit acceleration; LIHC cis rs2204008 0.575 rs10444564 chr12:38043782 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.75 0.3 1.99e-8 Bladder cancer; LIHC cis rs61041384 0.661 rs74240781 chr12:123792701 T/C cg00376283 chr12:123451042 ABCB9 -0.62 -6.58 -0.34 1.8e-10 Schizophrenia; LIHC cis rs7192380 0.624 rs11075730 chr16:69650522 C/T cg15192750 chr16:69999425 NA 0.37 5.78 0.3 1.69e-8 Sjögren's syndrome; LIHC cis rs10792665 0.575 rs7101888 chr11:82559984 T/C cg24227371 chr11:82718527 RAB30 -0.27 -6.56 -0.33 2e-10 Obesity-related traits; LIHC cis rs2108622 0.727 rs12611242 chr19:15978564 G/A cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.87e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs4803468 1.000 rs1473248 chr19:41923314 C/T cg09537434 chr19:41945824 ATP5SL 1.02 21.64 0.76 5.09e-66 Height; LIHC cis rs8180040 0.615 rs13062681 chr3:47021124 A/G cg16586182 chr3:47516702 SCAP -0.48 -8.63 -0.42 2.31e-16 Colorectal cancer; LIHC cis rs1008375 0.966 rs4698619 chr4:17580955 G/A cg16339924 chr4:17578868 LAP3 0.46 6.31 0.32 8.79e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3796352 0.881 rs35385050 chr3:52997945 C/A cg04865290 chr3:52927548 TMEM110 -0.53 -6.14 -0.31 2.33e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs3806843 0.735 rs801167 chr5:140081423 A/G cg19875535 chr5:140030758 IK 0.41 6.63 0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs12824058 0.831 rs12310049 chr12:130811260 C/G cg26677194 chr12:130822605 PIWIL1 0.52 7.36 0.37 1.36e-12 Menopause (age at onset); LIHC cis rs12908161 0.959 rs1051168 chr15:85200520 G/T cg17507749 chr15:85114479 UBE2QP1 0.68 7.72 0.39 1.31e-13 Schizophrenia; LIHC cis rs67981189 0.613 rs4366661 chr14:71452316 A/T cg15816911 chr14:71606274 NA -0.41 -6.81 -0.35 4.4e-11 Schizophrenia; LIHC cis rs8141529 0.702 rs132536 chr22:29302906 A/G cg02153584 chr22:29168773 CCDC117 -0.53 -8.31 -0.41 2.27e-15 Lymphocyte counts; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg01696603 chr6:125623444 HDDC2 0.57 6.24 0.32 1.3e-9 Mean platelet volume; LIHC cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.33 5.96 0.31 6.29e-9 Aortic root size; LIHC cis rs55702914 0.625 rs787989 chr2:198200123 G/A cg03934865 chr2:198174659 NA -0.41 -5.96 -0.31 6.44e-9 Major depression and alcohol dependence; LIHC cis rs73001065 0.551 rs10424702 chr19:19508013 A/G cg03709012 chr19:19516395 GATAD2A 0.74 8.45 0.42 8.61e-16 LDL cholesterol; LIHC cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg13607699 chr17:42295918 UBTF 0.48 7.67 0.38 1.75e-13 Total body bone mineral density; LIHC cis rs700651 0.821 rs771005 chr2:198675948 C/T cg10820045 chr2:198174542 NA 0.47 7.03 0.36 1.12e-11 Intracranial aneurysm; LIHC cis rs7428 0.545 rs9248 chr2:85537312 G/A cg24342717 chr2:85555507 TGOLN2 -0.77 -10.77 -0.5 1.73e-23 Ear protrusion; LIHC cis rs62573167 0.547 rs17063622 chr9:80037320 A/G cg14445849 chr9:79791814 VPS13A;LOC100286938 0.36 6.01 0.31 4.75e-9 Reticulocyte count; LIHC cis rs11122272 0.735 rs2491410 chr1:231532287 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.44 0.45 6.18e-19 Hemoglobin concentration; LIHC cis rs7959452 0.901 rs1384 chr12:69747834 C/T cg22834771 chr12:69754056 YEATS4 -0.37 -5.96 -0.31 6.23e-9 Blood protein levels; LIHC cis rs2637266 1.000 rs12260379 chr10:78365036 C/T cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.17e-8 Pulmonary function; LIHC cis rs7149337 0.773 rs3007067 chr14:51596420 G/A cg23942311 chr14:51606299 NA 0.35 7.29 0.37 2.17e-12 Cancer; LIHC cis rs10792665 0.575 rs10792654 chr11:82560445 T/G cg24227371 chr11:82718527 RAB30 -0.26 -6.07 -0.31 3.46e-9 Obesity-related traits; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs8060686 0.565 rs11555011 chr16:68088485 A/G cg05110241 chr16:68378359 PRMT7 -0.6 -6.94 -0.35 2.02e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.1 0.4 9.76e-15 Height; LIHC cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs5769765 0.908 rs9616388 chr22:50313438 T/C cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg17372223 chr3:52568218 NT5DC2 0.36 5.99 0.31 5.43e-9 Electroencephalogram traits; LIHC cis rs1577917 0.958 rs4707229 chr6:86546237 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.08 -0.4 1.09e-14 Response to antipsychotic treatment; LIHC cis rs10883723 0.668 rs12414407 chr10:104387019 A/G cg22532475 chr10:104410764 TRIM8 0.3 5.86 0.3 1.06e-8 Allergic disease (asthma, hay fever or eczema); LIHC cis rs919433 0.963 rs1366837 chr2:198160501 T/C cg10820045 chr2:198174542 NA -0.61 -10.32 -0.49 6.7e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1757171 0.504 rs11969056 chr6:37484285 C/T cg25019722 chr6:37503610 NA -0.33 -5.89 -0.3 9.46e-9 Cognitive performance; LIHC cis rs2842992 0.724 rs2273823 chr6:160211485 T/C cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs7572733 0.576 rs4850441 chr2:198913413 A/G cg00792783 chr2:198669748 PLCL1 -0.42 -5.93 -0.31 7.4e-9 Dermatomyositis; LIHC cis rs875971 0.502 rs1796227 chr7:66087019 G/C cg11764359 chr7:65958608 NA -0.62 -8.81 -0.43 6.39e-17 Aortic root size; LIHC cis rs17106184 1.000 rs12075991 chr1:51252618 A/G cg07174182 chr1:51127561 FAF1 -0.71 -8.19 -0.41 5.08e-15 Type 2 diabetes; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19748516 chr19:18684528 UBA52 0.44 6.09 0.31 3.12e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs9929218 0.954 rs60302411 chr16:68824220 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.26 -0.41 3.28e-15 Colorectal cancer; LIHC cis rs9858542 1.000 rs9812791 chr3:49682311 G/A cg03060546 chr3:49711283 APEH -0.63 -8.48 -0.42 6.94e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9399135 0.967 rs1854865 chr6:135360300 C/G cg24558204 chr6:135376177 HBS1L 0.42 6.82 0.35 4.09e-11 Red blood cell count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08132132 chr8:82644559 CHMP4C 0.39 6.29 0.32 9.89e-10 Cognitive function; LIHC cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg19318889 chr4:1322082 MAEA 0.52 8.77 0.43 8.86e-17 Obesity-related traits; LIHC trans rs7613875 0.600 rs1138536 chr3:50153356 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.41 6.24 0.32 1.26e-9 Body mass index; LIHC cis rs9309473 0.583 rs6705203 chr2:73574600 T/C cg20560298 chr2:73613845 ALMS1 -0.42 -6.53 -0.33 2.37e-10 Metabolite levels; LIHC cis rs6782228 0.606 rs2811488 chr3:128336517 C/T cg16766828 chr3:128327626 NA -0.39 -6.19 -0.32 1.69e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs8064024 0.650 rs12926178 chr16:4905915 C/T cg08329684 chr16:4932620 PPL -0.34 -5.83 -0.3 1.26e-8 Cancer; LIHC cis rs9309473 1.000 rs2901438 chr2:73665656 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.93 -0.35 2.16e-11 Metabolite levels; LIHC cis rs6693567 0.586 rs9661040 chr1:150483236 A/C cg15654264 chr1:150340011 RPRD2 0.52 8.91 0.43 3.19e-17 Migraine; LIHC cis rs10744422 1.000 rs936083 chr12:123338964 A/G cg18912006 chr12:123335444 HIP1R -0.64 -7.67 -0.38 1.78e-13 Schizophrenia; LIHC cis rs6430585 0.591 rs12476135 chr2:136486340 T/C cg07169764 chr2:136633963 MCM6 0.75 9.4 0.45 8.12e-19 Corneal structure; LIHC cis rs743757 1.000 rs2236957 chr3:50440426 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.53 8.38 0.41 1.38e-15 Diastolic blood pressure; LIHC cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg04083430 chr16:4736063 MGRN1 -0.44 -5.84 -0.3 1.19e-8 Schizophrenia; LIHC cis rs4975709 0.589 rs4975707 chr5:1864028 C/T cg15595755 chr5:1867978 NA 0.41 8.23 0.41 3.9e-15 Cardiovascular disease risk factors; LIHC cis rs11122272 0.735 rs2749699 chr1:231520279 A/C cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs9470366 0.848 rs66761782 chr6:36636080 T/C cg08179530 chr6:36648295 CDKN1A 0.56 6.67 0.34 1.02e-10 QRS duration; LIHC cis rs6964587 1.000 rs6976122 chr7:91610962 T/C cg17063962 chr7:91808500 NA 1.01 19.32 0.72 9.73e-57 Breast cancer; LIHC cis rs1419980 0.643 rs7296689 chr12:7779241 G/A cg10578777 chr12:7781093 NA -0.4 -5.83 -0.3 1.26e-8 HDL cholesterol levels; LIHC cis rs9814567 1.000 rs13090969 chr3:134307257 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.17 0.55 1.54e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7911264 1.000 rs7911264 chr10:94436851 C/T cg25506282 chr10:94462361 NA -0.43 -7.39 -0.37 1.16e-12 Inflammatory bowel disease; LIHC cis rs7503807 0.935 rs7215534 chr17:78612119 C/T cg09596252 chr17:78655493 RPTOR 0.38 6.89 0.35 2.62e-11 Obesity; LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg00280220 chr17:61926910 NA 0.41 6.46 0.33 3.61e-10 Prudent dietary pattern; LIHC cis rs4888262 0.545 rs7342732 chr16:74698716 A/C cg01733217 chr16:74700730 RFWD3 0.86 17.99 0.7 2.19e-51 Testicular germ cell tumor; LIHC cis rs17021463 0.902 rs34465979 chr4:95257554 C/A cg11021082 chr4:95130006 SMARCAD1 0.45 8.28 0.41 2.77e-15 Testicular germ cell tumor; LIHC cis rs782590 0.620 rs4322879 chr2:55797033 G/T cg18811423 chr2:55921094 PNPT1 -0.51 -7.64 -0.38 2.23e-13 Metabolic syndrome; LIHC cis rs4684776 0.935 rs13059407 chr3:11377345 G/C cg00170343 chr3:11313890 ATG7 -0.49 -6.72 -0.34 7.43e-11 Small vessel stroke; LIHC cis rs2599510 0.748 rs6718214 chr2:32550485 T/C cg02381751 chr2:32503542 YIPF4 -0.51 -6.95 -0.35 1.9e-11 Interleukin-18 levels; LIHC cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg27286337 chr10:134555280 INPP5A 0.93 12.65 0.56 2.45e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6840360 1.000 rs7439465 chr4:152594814 C/T cg22705602 chr4:152727874 NA 0.29 6.08 0.31 3.18e-9 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.649 rs139559 chr22:42191636 A/G cg06634786 chr22:41940651 POLR3H -0.57 -6.12 -0.31 2.53e-9 Vitiligo; LIHC cis rs826838 0.834 rs2387842 chr12:38736442 T/C cg13010199 chr12:38710504 ALG10B 0.65 7.98 0.4 2.17e-14 Heart rate; LIHC cis rs1395 0.922 rs11898114 chr2:27515527 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.01 -0.31 4.81e-9 Blood metabolite levels; LIHC cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg03517284 chr6:25882590 NA -0.67 -8.24 -0.41 3.73e-15 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg08888203 chr3:10149979 C3orf24 0.62 6.74 0.34 6.91e-11 Alzheimer's disease; LIHC cis rs4891159 0.790 rs1787448 chr18:74113179 T/C cg24786174 chr18:74118243 ZNF516 0.78 14.41 0.61 3.99e-37 Longevity; LIHC cis rs7044106 0.791 rs7043969 chr9:123493989 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.6 9.34 0.45 1.31e-18 Hip circumference adjusted for BMI; LIHC cis rs2066819 1.000 rs11575229 chr12:56750737 C/T cg26714650 chr12:56694279 CS -1.35 -12.74 -0.57 1.09e-30 Psoriasis vulgaris; LIHC cis rs7624766 0.508 rs9831287 chr3:160579248 A/G cg03342759 chr3:160939853 NMD3 -0.41 -5.83 -0.3 1.27e-8 Response to methotrexate in rheumatoid arthritis; LIHC cis rs74544699 1.000 rs79981249 chr4:74784164 T/C cg02530824 chr4:74847766 PF4 0.66 6.82 0.35 4.2e-11 Growth-regulated protein alpha levels; LIHC cis rs6582630 0.502 rs7311700 chr12:38463232 T/A cg26384229 chr12:38710491 ALG10B 0.9 11.48 0.53 5.09e-26 Drug-induced liver injury (flucloxacillin); LIHC cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg05564831 chr3:52568323 NT5DC2 0.37 6.03 0.31 4.19e-9 Bipolar disorder; LIHC cis rs9916302 0.904 rs9892055 chr17:37510402 C/T cg00129232 chr17:37814104 STARD3 0.38 6.15 0.32 2.21e-9 Glomerular filtration rate (creatinine); LIHC cis rs4908768 0.906 rs12568293 chr1:8540912 C/T cg25722041 chr1:8623473 RERE -0.4 -5.95 -0.31 6.65e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs34172651 0.517 rs8059004 chr16:24837905 G/A cg00152838 chr16:24741724 TNRC6A -0.53 -6.38 -0.33 5.63e-10 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.754 rs28663627 chr11:50048829 C/T cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs11030122 0.702 rs7950153 chr11:3951337 T/C cg18678763 chr11:4115507 RRM1 -0.55 -8.25 -0.41 3.39e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs13161895 1.000 rs34882290 chr5:179463836 C/A cg02702477 chr5:179499311 RNF130 0.75 10.44 0.49 2.46e-22 LDL cholesterol; LIHC cis rs8180040 0.903 rs7636423 chr3:47309134 C/G cg16586182 chr3:47516702 SCAP -0.54 -9.77 -0.47 4.79e-20 Colorectal cancer; LIHC cis rs7131987 0.617 rs3764953 chr12:29502236 T/C cg12903224 chr12:29470962 FAR2 -0.41 -6.46 -0.33 3.54e-10 QT interval; LIHC cis rs1664789 0.901 rs702635 chr5:53270188 G/T ch.5.1024479R chr5:53302184 ARL15 0.47 7.44 0.37 8.32e-13 Waist circumference adjusted for body mass index; LIHC cis rs3736594 0.513 rs6704596 chr2:27796927 A/G cg27432699 chr2:27873401 GPN1 0.46 6.76 0.34 6.12e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC trans rs1814175 0.645 rs11040702 chr11:50024827 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg07404485 chr7:94953653 PON1 -0.43 -7.61 -0.38 2.67e-13 Paraoxonase activity; LIHC cis rs595982 0.527 rs55670257 chr19:49382654 G/A cg21252483 chr19:49399788 TULP2 -0.98 -10.91 -0.51 5.59e-24 Red cell distribution width; LIHC cis rs7772486 0.764 rs2265471 chr6:146220250 G/A cg05347473 chr6:146136440 FBXO30 0.36 5.83 0.3 1.27e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs13217239 0.646 rs10946888 chr6:26951678 A/G cg12292205 chr6:26970375 C6orf41 0.44 7.69 0.38 1.53e-13 Schizophrenia; LIHC cis rs9583531 0.689 rs4773244 chr13:111383937 A/T cg15841412 chr13:111365552 ING1 -0.5 -6.37 -0.33 6.24e-10 Coronary artery disease; LIHC cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg04944784 chr2:26401820 FAM59B -0.72 -9.14 -0.44 5.77e-18 Gut microbiome composition (summer); LIHC cis rs9790314 0.747 rs1610158 chr3:160815050 A/G cg03342759 chr3:160939853 NMD3 0.69 9.33 0.45 1.4e-18 Morning vs. evening chronotype; LIHC cis rs240764 0.658 rs12194255 chr6:101168439 G/A cg09795085 chr6:101329169 ASCC3 -0.39 -5.71 -0.3 2.41e-8 Neuroticism; LIHC cis rs12744310 1.000 rs12031169 chr1:41768251 A/G cg03962019 chr1:41807865 NA 0.4 6.49 0.33 3.01e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01538066 chr19:57946466 ZNF749 -0.52 -6.18 -0.32 1.85e-9 Systolic blood pressure; LIHC cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg24209194 chr3:40518798 ZNF619 0.63 9.73 0.47 6.73e-20 Renal cell carcinoma; LIHC cis rs875971 0.543 rs801191 chr7:66032955 G/A cg14393609 chr7:65229607 NA -0.35 -5.71 -0.3 2.4e-8 Aortic root size; LIHC cis rs6459804 1.000 rs58278053 chr7:157512934 A/T cg05731713 chr7:157510257 PTPRN2 0.24 6.62 0.34 1.39e-10 Bipolar disorder and schizophrenia; LIHC cis rs2635047 0.638 rs12968552 chr18:44702502 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.42 5.98 0.31 5.65e-9 Educational attainment; LIHC cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.47 0.56 1.09e-29 Prudent dietary pattern; LIHC cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg08417687 chr6:108582627 SNX3 -0.56 -6.13 -0.31 2.41e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs7674212 0.539 rs6821617 chr4:104128410 G/A cg16532752 chr4:104119610 CENPE -0.46 -7.26 -0.37 2.58e-12 Type 2 diabetes; LIHC cis rs1904096 0.513 rs2632405 chr4:95152215 T/G cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.02 -0.44 1.33e-17 Type 2 diabetes; LIHC cis rs6952808 0.743 rs10266703 chr7:1918941 C/A cg14004847 chr7:1930337 MAD1L1 -0.48 -6.74 -0.34 6.73e-11 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg06873352 chr17:61820015 STRADA 0.75 13.24 0.58 1.32e-32 Prudent dietary pattern; LIHC cis rs7674212 0.570 rs6813563 chr4:104099110 G/A cg16532752 chr4:104119610 CENPE -0.45 -7.08 -0.36 8.12e-12 Type 2 diabetes; LIHC cis rs35883536 0.900 rs7520474 chr1:101091376 T/C cg14515779 chr1:101123966 NA 0.64 11.96 0.54 8.49e-28 Monocyte count; LIHC cis rs11229555 0.645 rs12801475 chr11:58189034 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9611565 0.506 rs1984839 chr22:41685937 G/C cg03806693 chr22:41940476 POLR3H -0.7 -8.26 -0.41 3.21e-15 Vitiligo; LIHC cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg04025307 chr7:1156635 C7orf50 0.57 9.32 0.45 1.48e-18 Longevity;Endometriosis; LIHC cis rs6570726 0.791 rs6900040 chr6:145893134 C/T cg23711669 chr6:146136114 FBXO30 0.72 12.8 0.57 6.26e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs2152348 chr6:8474301 C/A cg23788917 chr6:8435910 SLC35B3 0.59 8.42 0.41 1.06e-15 Motion sickness; LIHC cis rs9296092 0.500 rs9469504 chr6:33527243 G/A cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg03452623 chr4:187889614 NA -0.32 -8.31 -0.41 2.33e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs6942756 1.000 rs2012919 chr7:128890812 C/T cg02491457 chr7:128862824 NA -0.7 -11.43 -0.53 7.42e-26 White matter hyperintensity burden; LIHC cis rs8017423 0.967 rs59980414 chr14:90687738 G/C cg14092571 chr14:90743983 NA -0.38 -6.05 -0.31 3.86e-9 Mortality in heart failure; LIHC trans rs1814175 0.817 rs28679516 chr11:50055998 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.01 0.35 1.3e-11 Height; LIHC cis rs1008375 0.902 rs6844984 chr4:17651304 C/G cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.64e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4665809 0.878 rs892448 chr2:26366205 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.78 -9.79 -0.47 3.97e-20 Gut microbiome composition (summer); LIHC cis rs6459788 0.693 rs11981578 chr7:157250133 C/T cg06271696 chr7:157225062 NA -0.5 -7.99 -0.4 2.07e-14 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs7542091 0.666 rs7537070 chr1:210043565 A/G cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC cis rs9309711 0.623 rs4641971 chr2:3481857 A/C cg15506890 chr2:3487001 NA 0.54 8.63 0.42 2.31e-16 Neurofibrillary tangles; LIHC cis rs4319547 0.656 rs7397299 chr12:122821649 G/T cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.46 -0.37 7.18e-13 Body mass index; LIHC cis rs11958404 0.860 rs72818117 chr5:157441130 G/A cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs10779751 0.734 rs2791650 chr1:11132541 G/C cg08854313 chr1:11322531 MTOR 0.66 10.07 0.48 4.8e-21 Body mass index; LIHC cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg18404041 chr3:52824283 ITIH1 -0.47 -7.91 -0.39 3.56e-14 Bipolar disorder; LIHC cis rs713477 0.692 rs8019270 chr14:55907172 C/G cg13175173 chr14:55914753 NA -0.31 -6.72 -0.34 7.76e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg16405210 chr4:1374714 KIAA1530 -0.41 -6.11 -0.31 2.73e-9 Obesity-related traits; LIHC cis rs6570726 0.755 rs2092297 chr6:145893765 A/G cg23711669 chr6:146136114 FBXO30 0.71 12.67 0.57 1.93e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs10870270 0.956 rs11146325 chr10:133767529 A/G cg17892150 chr10:133769511 PPP2R2D -0.68 -12.84 -0.57 4.5e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7944735 0.508 rs4752786 chr11:47628536 C/T cg20307385 chr11:47447363 PSMC3 -0.55 -6.32 -0.32 7.94e-10 Intraocular pressure; LIHC cis rs9911578 1.000 rs2567905 chr17:56782297 T/C cg12560992 chr17:57184187 TRIM37 0.99 17.94 0.7 3.45e-51 Intelligence (multi-trait analysis); LIHC cis rs929354 1.000 rs1182389 chr7:157038803 C/T cg17757837 chr7:157058334 UBE3C 0.79 13.97 0.6 2.14e-35 Body mass index; LIHC trans rs6598955 0.671 rs11247901 chr1:26612693 T/A cg07461501 chr17:79650226 HGS;ARL16 -0.75 -8.73 -0.43 1.14e-16 Obesity-related traits; LIHC cis rs2204008 0.577 rs2623049 chr12:38018831 G/A cg26384229 chr12:38710491 ALG10B -0.49 -6.86 -0.35 3.33e-11 Bladder cancer; LIHC cis rs559928 0.597 rs947939 chr11:63885287 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.73 6.4 0.33 5.21e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs4319547 1.000 rs6489071 chr12:123025576 C/G cg23029597 chr12:123009494 RSRC2 -0.53 -7.43 -0.37 9.02e-13 Body mass index; LIHC cis rs7917772 0.582 rs729024 chr10:104341975 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs713477 0.618 rs6573033 chr14:55919060 C/G cg13175173 chr14:55914753 NA -0.3 -6.76 -0.34 6.11e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs9649213 0.593 rs13307593 chr7:97986146 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs6088813 1.000 rs4911494 chr20:33971914 C/T cg14752227 chr20:34000481 UQCC -0.41 -5.83 -0.3 1.25e-8 Height; LIHC cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg05590025 chr7:65112418 INTS4L2 -0.6 -6.65 -0.34 1.14e-10 Diabetic kidney disease; LIHC cis rs4308124 0.708 rs6716091 chr2:111991133 C/T cg04571233 chr2:111982156 NA -0.48 -5.85 -0.3 1.15e-8 Vitiligo; LIHC trans rs7246657 0.943 rs4969487 chr19:37831039 C/T cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs2075371 0.933 rs1868784 chr7:133945932 A/G cg20476274 chr7:133979776 SLC35B4 0.7 11.65 0.53 1.25e-26 Mean platelet volume; LIHC cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.05 13.33 0.58 6.23e-33 Alzheimer's disease; LIHC cis rs10256972 0.758 rs9801444 chr7:1080444 A/C cg23978390 chr7:1156363 C7orf50 -0.52 -7.41 -0.37 9.96e-13 Longevity;Endometriosis; LIHC cis rs970821 0.900 rs2008198 chr8:124754567 T/C cg00283535 chr8:124749564 ANXA13 0.37 6.05 0.31 3.78e-9 Breast cancer; LIHC cis rs2455799 0.574 rs2455798 chr3:15700505 G/C cg12698662 chr3:15914712 MIR563 -0.36 -6.63 -0.34 1.34e-10 Mean platelet volume; LIHC cis rs1577917 0.740 rs9344542 chr6:86393905 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.37 6.8 0.35 4.65e-11 Response to antipsychotic treatment; LIHC cis rs858239 0.600 rs2014768 chr7:23122440 C/A cg23682824 chr7:23144976 KLHL7 0.46 6.95 0.35 1.89e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs2727020 0.617 rs1917311 chr11:49422665 C/T cg03929089 chr4:120376271 NA -0.87 -16.87 -0.67 6.67e-47 Coronary artery disease; LIHC cis rs1267303 0.642 rs61783087 chr1:46999955 T/C cg25110126 chr1:46999211 NA 0.52 7.18 0.36 4.4e-12 Monobrow; LIHC cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg08499158 chr17:42289980 UBTF -0.52 -8.46 -0.42 8.15e-16 Total body bone mineral density; LIHC cis rs6062302 0.549 rs4809586 chr20:62249402 C/T cg16989086 chr20:62203971 PRIC285 0.57 8.25 0.41 3.51e-15 Glioblastoma; LIHC cis rs1790761 0.692 rs614080 chr11:67347287 G/A cg21734168 chr11:67353974 GSTP1 -0.28 -6.88 -0.35 2.94e-11 Mean corpuscular volume; LIHC cis rs6466055 0.777 rs2299308 chr7:104825819 A/C cg04380332 chr7:105027541 SRPK2 -0.34 -6.42 -0.33 4.59e-10 Schizophrenia; LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg16132339 chr22:24313637 DDTL;DDT 0.73 14.3 0.61 1.09e-36 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs875971 0.862 rs4149461 chr7:65744732 T/C cg18252515 chr7:66147081 NA 0.44 6.33 0.32 7.52e-10 Aortic root size; LIHC cis rs6674176 0.628 rs3828146 chr1:44428715 C/T cg12908607 chr1:44402522 ARTN -0.5 -8.36 -0.41 1.55e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs17106184 0.818 rs112095647 chr1:51237302 C/G cg07174182 chr1:51127561 FAF1 -0.61 -6.65 -0.34 1.16e-10 Type 2 diabetes; LIHC cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.54 8.11 0.4 9.33e-15 Menarche (age at onset); LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg22520471 chr17:61851767 DDX42;CCDC47 -0.53 -7.78 -0.39 8.63e-14 Height; LIHC cis rs79149102 0.579 rs7168638 chr15:75280826 T/C cg17294928 chr15:75287854 SCAMP5 -0.51 -6.56 -0.33 2.03e-10 Lung cancer; LIHC cis rs7208859 0.573 rs73277960 chr17:29177441 T/C cg14067834 chr17:29058358 SUZ12P 0.66 6.55 0.33 2.18e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7529073 0.545 rs340884 chr1:214145389 T/C cg24083324 chr1:214162604 PROX1 0.49 7.47 0.37 6.79e-13 Schizophrenia; LIHC cis rs9787249 0.957 rs6670841 chr1:40220284 C/G cg02773041 chr1:40204384 PPIE 0.41 5.89 0.3 9.04e-9 Blood protein levels; LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg03854865 chr6:26224070 HIST1H3E 0.63 7.23 0.36 3.28e-12 Gout;Renal underexcretion gout; LIHC cis rs10131894 0.611 rs175002 chr14:75436466 C/G cg11812906 chr14:75593930 NEK9 0.61 10.66 0.5 4.39e-23 Coronary artery disease; LIHC cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11252926 0.604 rs2050970 chr10:515870 C/T cg09445902 chr10:555545 DIP2C -0.39 -6.33 -0.32 7.73e-10 Psychosis in Alzheimer's disease; LIHC cis rs12908161 0.920 rs12904605 chr15:85201419 T/C cg03959625 chr15:84868606 LOC388152 0.45 6.21 0.32 1.55e-9 Schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01154392 chr12:48167362 SLC48A1 0.59 7.16 0.36 5.02e-12 Hepatitis; LIHC cis rs796364 1.000 rs796364 chr2:200716119 C/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.01 0.44 1.48e-17 Schizophrenia; LIHC cis rs3809863 0.602 rs11650072 chr17:45393665 A/G cg08085267 chr17:45401833 C17orf57 -0.64 -9.94 -0.47 1.28e-20 Glaucoma (primary open-angle); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06665941 chr21:34602869 IFNAR2 0.46 7.28 0.37 2.32e-12 Pancreatic cancer; LIHC cis rs9814567 1.000 rs9835204 chr3:134261342 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs999943 0.846 rs9357162 chr6:33613344 G/A cg14003231 chr6:33640908 ITPR3 0.37 7.85 0.39 5.49e-14 Obesity (extreme); LIHC cis rs7927771 0.690 rs35496532 chr11:47450338 C/T cg20135002 chr11:47629003 NA -0.56 -9.52 -0.46 3.18e-19 Subjective well-being; LIHC cis rs73001065 0.591 rs56273306 chr19:19621004 T/C cg03709012 chr19:19516395 GATAD2A 0.9 9.62 0.46 1.5e-19 LDL cholesterol; LIHC cis rs7249142 0.562 rs10417796 chr19:19287072 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.45 -7.6 -0.38 2.94e-13 IgG glycosylation; LIHC cis rs2153535 0.580 rs9379213 chr6:8474945 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs801193 0.844 rs7779971 chr7:66161790 T/C cg00343986 chr7:65444356 GUSB 0.39 5.77 0.3 1.76e-8 Aortic root size; LIHC cis rs61008539 0.741 rs11767322 chr7:867405 A/G cg00934597 chr7:893267 UNC84A -0.5 -6.25 -0.32 1.22e-9 Perceived unattractiveness to mosquitoes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22159483 chr17:1588198 PRPF8 0.44 6.94 0.35 1.93e-11 Cognitive function; LIHC cis rs35306767 0.855 rs56222464 chr10:867535 C/G cg10556349 chr10:835070 NA 0.67 5.85 0.3 1.13e-8 Eosinophil percentage of granulocytes; LIHC cis rs68092024 0.704 rs792832 chr3:99474862 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.87 0.3 1.03e-8 Cleft lip with or without cleft palate; LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.15 0.4 6.89e-15 Height; LIHC cis rs9457247 1.000 rs402749 chr6:167386104 C/T cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg09244754 chr6:122792965 PKIB;SERINC1 -0.4 -6.21 -0.32 1.51e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg07424592 chr7:64974309 NA -0.82 -9.4 -0.45 7.95e-19 Diabetic kidney disease; LIHC cis rs782590 0.559 rs12617719 chr2:55915826 G/C cg03859395 chr2:55845619 SMEK2 -0.54 -9.18 -0.44 4.24e-18 Metabolic syndrome; LIHC cis rs75908454 1.000 rs79325961 chr6:169934196 T/C cg19338460 chr6:170058176 WDR27 -0.83 -7.75 -0.39 1.04e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs11997175 0.846 rs11776207 chr8:33765126 G/T ch.8.33884649F chr8:33765107 NA -0.51 -8.19 -0.41 5.18e-15 Body mass index; LIHC trans rs11148252 0.595 rs9526974 chr13:53251040 C/G cg18335740 chr13:41363409 SLC25A15 0.58 10.81 0.5 1.31e-23 Lewy body disease; LIHC trans rs61931739 0.534 rs10844819 chr12:34261389 G/T cg26384229 chr12:38710491 ALG10B 0.56 7.15 0.36 5.39e-12 Morning vs. evening chronotype; LIHC cis rs2242116 0.796 rs4683297 chr3:46973673 T/C cg02527881 chr3:46936655 PTH1R 0.45 9.1 0.44 7.45e-18 Birth weight; LIHC cis rs13108904 0.818 rs3775099 chr4:1232510 C/G cg00684032 chr4:1343700 KIAA1530 0.46 6.75 0.34 6.42e-11 Obesity-related traits; LIHC cis rs7772486 0.727 rs12190966 chr6:146146820 T/G cg05347473 chr6:146136440 FBXO30 0.37 6.14 0.32 2.28e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.0 20.47 0.74 2.34e-61 Height; LIHC cis rs2075165 0.901 rs1804999 chr1:156219450 A/G cg08469215 chr1:156261351 TMEM79 0.37 5.89 0.3 9.37e-9 Tonsillectomy; LIHC cis rs9549367 0.789 rs3794422 chr13:113893729 G/A cg00898013 chr13:113819073 PROZ -0.43 -7.43 -0.37 9e-13 Platelet distribution width; LIHC cis rs3892630 0.824 rs2287884 chr19:33321447 A/G cg22980127 chr19:33182716 NUDT19 0.99 11.88 0.54 1.71e-27 Red blood cell traits; LIHC cis rs4808199 1.000 rs60321073 chr19:19499598 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.44 6.25 0.32 1.19e-9 Nonalcoholic fatty liver disease; LIHC cis rs763121 0.962 rs6001159 chr22:38966487 A/G cg06022373 chr22:39101656 GTPBP1 0.65 12.47 0.56 1.16e-29 Menopause (age at onset); LIHC cis rs9818758 0.607 rs13068038 chr3:49294250 C/A cg00383909 chr3:49044727 WDR6 0.79 6.68 0.34 9.53e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs10276381 0.579 rs9648026 chr7:28161983 A/G cg23620719 chr7:28220237 JAZF1 -0.59 -6.67 -0.34 1e-10 Crohn's disease; LIHC cis rs7520050 0.931 rs6698247 chr1:46371486 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.92 0.3 7.9e-9 Red blood cell count;Reticulocyte count; LIHC trans rs61931739 0.553 rs68124042 chr12:34064431 C/A cg26384229 chr12:38710491 ALG10B 0.49 6.82 0.35 4.04e-11 Morning vs. evening chronotype; LIHC cis rs860295 1.000 rs708611 chr1:155743310 A/C cg02153340 chr1:155202674 NA 0.31 5.86 0.3 1.09e-8 Body mass index; LIHC cis rs700651 0.821 rs4850812 chr2:198743655 G/T cg10820045 chr2:198174542 NA -0.47 -6.97 -0.35 1.6e-11 Intracranial aneurysm; LIHC cis rs7474896 0.583 rs34185758 chr10:37990854 T/C cg25427524 chr10:38739819 LOC399744 -0.49 -7.17 -0.36 4.53e-12 Obesity (extreme); LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg03395511 chr6:291903 DUSP22 -0.53 -7.32 -0.37 1.75e-12 Menopause (age at onset); LIHC cis rs815815 0.608 rs815808 chr2:47381097 C/T cg27223769 chr2:47403360 CALM2 0.46 5.92 0.3 7.99e-9 Dialysis-related mortality; LIHC cis rs7107174 0.786 rs4945262 chr11:77990831 T/C cg02023728 chr11:77925099 USP35 0.51 9.62 0.46 1.5700000000000001e-19 Testicular germ cell tumor; LIHC cis rs727505 1.000 rs10226033 chr7:124521430 C/A cg23710748 chr7:124431027 NA -0.33 -5.82 -0.3 1.37e-8 Lewy body disease; LIHC cis rs2274273 0.870 rs61210954 chr14:55765402 T/C cg01864836 chr14:55583639 NA -0.4 -7.38 -0.37 1.18e-12 Protein biomarker; LIHC cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg14393609 chr7:65229607 NA -0.44 -6.55 -0.33 2.06e-10 Aortic root size; LIHC cis rs7715806 0.500 rs34355 chr5:74959970 G/A cg06933384 chr5:74808293 COL4A3BP;POLK -0.43 -6.29 -0.32 9.77e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7677751 0.806 rs7698425 chr4:55090656 C/T cg17187183 chr4:55093834 PDGFRA 0.66 8.37 0.41 1.54e-15 Corneal astigmatism; LIHC cis rs16828019 0.929 rs35813191 chr1:41742800 T/C cg20697417 chr1:41786797 NA 0.35 6.61 0.34 1.45e-10 Intelligence (multi-trait analysis); LIHC cis rs798554 0.660 rs2644295 chr7:2860217 A/C cg19717773 chr7:2847554 GNA12 -0.41 -7.43 -0.37 8.83e-13 Height; LIHC cis rs3815700 0.841 rs10410895 chr19:33093655 T/G cg02997394 chr19:33096574 ANKRD27 0.72 9.25 0.45 2.55e-18 Eosinophilic esophagitis; LIHC cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.53 -0.38 4.56e-13 Bipolar disorder; LIHC cis rs2282032 0.527 rs8004573 chr14:90765743 C/T cg04374321 chr14:90722782 PSMC1 0.49 7.07 0.36 8.56e-12 Longevity; LIHC cis rs6882046 0.513 rs447801 chr5:88002653 T/C cg22951263 chr5:87985283 NA -0.4 -7.09 -0.36 7.67e-12 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC trans rs2352908 0.786 rs68126816 chr14:49445734 C/A cg16568472 chr20:3190600 ITPA -0.46 -6.17 -0.32 1.94e-9 Social communication problems; LIHC trans rs7829975 0.871 rs777709 chr8:8583872 T/C cg21775007 chr8:11205619 TDH -0.43 -6.35 -0.32 7e-10 Mood instability; LIHC cis rs449303 1 rs449303 chr14:60605788 A/G cg00846580 chr14:60632234 DHRS7 0.78 7.57 0.38 3.48e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg25072359 chr17:41440525 NA -0.35 -5.86 -0.3 1.12e-8 Menopause (age at onset); LIHC cis rs6430585 0.527 rs76380759 chr2:136438517 G/A cg07169764 chr2:136633963 MCM6 0.67 8.55 0.42 4.05e-16 Corneal structure; LIHC cis rs4819052 0.765 rs2838852 chr21:46677037 C/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.67 0.38 1.81e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2204008 0.837 rs11172728 chr12:38070042 C/A cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg03517284 chr6:25882590 NA -0.64 -8.97 -0.44 1.95e-17 Blood metabolite levels; LIHC cis rs911119 0.955 rs8121405 chr20:23605226 G/A cg16589663 chr20:23618590 CST3 0.76 8.04 0.4 1.44e-14 Chronic kidney disease; LIHC cis rs1580019 0.520 rs6945238 chr7:32646096 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.9 -14.83 -0.63 9.37e-39 Cognitive ability; LIHC cis rs6502050 0.835 rs8073645 chr17:80110957 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg11663144 chr21:46675770 NA -0.34 -6.33 -0.32 7.74e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02632643 chr19:8370165 CD320 0.43 6.09 0.31 3.07e-9 Immature fraction of reticulocytes; LIHC cis rs1843834 0.858 rs2047136 chr2:225511361 A/T cg12698349 chr2:225449008 CUL3 0.45 5.97 0.31 5.9e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs10504229 0.679 rs78941440 chr8:58052095 A/G cg20607798 chr8:58055168 NA 0.46 6.43 0.33 4.2e-10 Developmental language disorder (linguistic errors); LIHC cis rs2204008 0.542 rs34770471 chr12:38009613 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs7914558 0.966 rs12569617 chr10:104729996 T/C cg15744005 chr10:104629667 AS3MT -0.41 -9.34 -0.45 1.23e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8084351 0.577 rs7506783 chr18:50625519 A/G cg24270629 chr18:50823537 DCC 0.42 6.43 0.33 4.18e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs10504073 0.584 rs4873306 chr8:49950369 T/C cg00325661 chr8:49890786 NA 0.33 7.61 0.38 2.73e-13 Blood metabolite ratios; LIHC trans rs11039798 0.588 rs11039818 chr11:48562120 C/T cg15704280 chr7:45808275 SEPT13 0.56 6.23 0.32 1.4e-9 Axial length; LIHC cis rs4728302 0.869 rs10224683 chr7:133590937 A/G cg10665199 chr7:133106180 EXOC4 -0.35 -6.02 -0.31 4.44e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs2842992 0.915 rs2842958 chr6:160108425 A/G cg26839252 chr6:160211577 TCP1;MRPL18 0.36 6.06 0.31 3.58e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs7542091 0.704 rs2142907 chr1:210039505 T/C cg22029157 chr1:209979665 IRF6 0.37 6.13 0.31 2.41e-9 Monobrow; LIHC cis rs7107174 0.688 rs11237490 chr11:78135229 C/T cg02023728 chr11:77925099 USP35 0.42 7.47 0.37 6.86e-13 Testicular germ cell tumor; LIHC cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg21877656 chr19:58662188 ZNF329 1.07 8.34 0.41 1.83e-15 Cholesterol, total; LIHC cis rs1866706 0.896 rs4757957 chr11:12881398 C/G cg25843174 chr11:12811716 TEAD1 -0.29 -6.08 -0.31 3.29e-9 Intelligence (multi-trait analysis); LIHC cis rs919433 0.854 rs13013049 chr2:198208664 C/T cg10820045 chr2:198174542 NA -0.56 -9.25 -0.45 2.44e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7666738 0.830 rs7694889 chr4:98855596 T/C cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs4808199 0.895 rs10421505 chr19:19459554 C/T cg03709012 chr19:19516395 GATAD2A 1.02 17.35 0.68 8.06e-49 Nonalcoholic fatty liver disease; LIHC cis rs6500602 0.826 rs9925719 chr16:4461861 A/G cg08645402 chr16:4508243 NA 0.34 5.74 0.3 2.07e-8 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27619136 chr4:174291353 SAP30 0.52 7.41 0.37 9.88e-13 Pancreatic cancer; LIHC cis rs4474465 0.850 rs10793327 chr11:78256841 A/C cg27205649 chr11:78285834 NARS2 0.39 6.09 0.31 3.11e-9 Alzheimer's disease (survival time); LIHC cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg23205692 chr1:25664452 TMEM50A 0.39 6.22 0.32 1.45e-9 Plateletcrit;Mean corpuscular volume; LIHC trans rs61931739 0.500 rs7310237 chr12:34483435 G/A cg26384229 chr12:38710491 ALG10B 0.63 8.13 0.4 8.07e-15 Morning vs. evening chronotype; LIHC cis rs1000083 0.915 rs9314193 chr5:96577154 A/G ch.5.96698337R chr5:96672581 NA 0.84 6.81 0.35 4.37e-11 Cisplatin-induced ototoxicity; LIHC cis rs9828933 0.938 rs2578011 chr3:64004819 C/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.79 -9.84 -0.47 2.7e-20 Type 2 diabetes; LIHC cis rs875971 0.545 rs1796222 chr7:66057154 T/C cg11764359 chr7:65958608 NA -0.61 -8.78 -0.43 7.77e-17 Aortic root size; LIHC cis rs7677751 0.806 rs7679903 chr4:55097373 T/C cg17187183 chr4:55093834 PDGFRA 0.68 8.53 0.42 4.89e-16 Corneal astigmatism; LIHC cis rs6582630 0.502 rs10880450 chr12:38440294 G/C cg26384229 chr12:38710491 ALG10B 0.58 8.19 0.4 5.43e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs6088580 0.609 rs6058029 chr20:32969643 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs9309711 0.643 rs4264589 chr2:3481098 G/T cg04359351 chr2:3481828 TTC15 0.28 5.91 0.3 8.31e-9 Neurofibrillary tangles; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06397381 chr3:12943820 IQSEC1 0.42 6.06 0.31 3.53e-9 Longevity; LIHC cis rs1552244 0.882 rs112621205 chr3:10017916 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs9733 0.791 rs11204693 chr1:150647987 C/T cg18016565 chr1:150552671 MCL1 -0.49 -10.21 -0.48 1.6e-21 Tonsillectomy; LIHC trans rs11098499 0.722 rs1814814 chr4:120258124 C/G cg25214090 chr10:38739885 LOC399744 0.47 7.7 0.38 1.52e-13 Corneal astigmatism; LIHC cis rs826838 0.967 rs7965656 chr12:38807244 G/A cg13010199 chr12:38710504 ALG10B 0.6 6.87 0.35 3.01e-11 Heart rate; LIHC cis rs9814567 0.806 rs9841371 chr3:134320765 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs896854 0.738 rs527234 chr8:95963798 C/G cg16049864 chr8:95962084 TP53INP1 0.57 9.44 0.45 6.09e-19 Type 2 diabetes; LIHC cis rs7613875 0.620 rs17657688 chr3:50033228 C/T cg21467203 chr3:49911342 NA 0.54 9.86 0.47 2.38e-20 Body mass index; LIHC cis rs7772486 0.754 rs13214277 chr6:146136125 G/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.6 -0.34 1.61e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs34779708 0.931 rs34876468 chr10:35424450 G/A cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1707322 0.717 rs10890345 chr1:46213927 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg21171335 chr12:122356390 WDR66 0.48 7.94 0.39 2.85e-14 Mean corpuscular volume; LIHC cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg11644478 chr21:40555479 PSMG1 -0.86 -10.66 -0.5 4.22e-23 Cognitive function; LIHC cis rs9733 0.596 rs6661872 chr1:150628357 C/G cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs7618501 1.000 rs9855505 chr3:49792158 T/G cg21467203 chr3:49911342 NA 0.39 6.63 0.34 1.28e-10 Intelligence (multi-trait analysis); LIHC cis rs155076 1.000 rs195570 chr13:21867580 T/G cg14456004 chr13:21872349 NA -1.26 -13.34 -0.58 5.91e-33 White matter hyperintensity burden; LIHC cis rs9868809 0.505 rs13316551 chr3:48745167 A/C cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.53e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs4925386 1.000 rs2151512 chr20:60913495 T/C cg24112000 chr20:60950667 NA 0.48 7.53 0.38 4.65e-13 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs5769765 0.773 rs58375955 chr22:50312630 A/G cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs950776 0.518 rs3813571 chr15:78832792 G/T cg06917634 chr15:78832804 PSMA4 0.91 13.9 0.6 3.76e-35 Sudden cardiac arrest; LIHC cis rs5821446 1 rs5821446 chr17:65962538 A/AT cg12091567 chr17:66097778 LOC651250 0.68 9.78 0.47 4.41e-20 Eosinophil percentage of granulocytes; LIHC cis rs11122272 0.735 rs2808611 chr1:231548480 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.67 10.58 0.5 7.76e-23 Hemoglobin concentration; LIHC cis rs11690935 0.959 rs6705200 chr2:172637600 A/G cg13550731 chr2:172543902 DYNC1I2 -0.95 -19.0 -0.72 1.79e-55 Schizophrenia; LIHC cis rs4919694 1.000 rs17727391 chr10:104836101 C/A cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs763121 0.853 rs6001182 chr22:39047443 A/G cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs2952156 0.920 rs2517955 chr17:37843681 C/T cg00129232 chr17:37814104 STARD3 -0.55 -10.43 -0.49 2.69e-22 Asthma; LIHC cis rs2842992 0.747 rs733319 chr6:160221475 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.65 0.56 2.41e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs9910055 0.529 rs228748 chr17:42174390 G/A cg16434002 chr17:42200994 HDAC5 0.45 5.77 0.3 1.73e-8 Total body bone mineral density; LIHC cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg18357526 chr6:26021779 HIST1H4A 0.52 7.33 0.37 1.71e-12 Blood metabolite levels; LIHC cis rs2439831 0.867 rs12324572 chr15:43636200 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.31 0.52 2.11e-25 Lung cancer in ever smokers; LIHC cis rs11608355 0.515 rs1045263 chr12:109974191 A/G cg05360138 chr12:110035743 NA 0.95 10.87 0.51 7.78e-24 Neuroticism; LIHC cis rs6952808 0.529 rs73038442 chr7:2139457 C/T cg02951883 chr7:2050386 MAD1L1 -0.65 -10.67 -0.5 3.98e-23 Bipolar disorder and schizophrenia; LIHC cis rs6964587 1.000 rs57816416 chr7:91736078 A/C cg17063962 chr7:91808500 NA 1.02 19.59 0.73 8.04e-58 Breast cancer; LIHC cis rs9296092 0.517 rs6911036 chr6:33471652 C/G cg13560919 chr6:33536144 NA -0.38 -6.06 -0.31 3.58e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs2573652 1.000 rs2581365 chr15:100513318 A/C cg09918751 chr15:100517450 ADAMTS17 -0.77 -13.58 -0.59 6.95e-34 Height; LIHC cis rs7959452 0.590 rs28778648 chr12:69771911 C/A cg20891283 chr12:69753455 YEATS4 0.9 19.46 0.72 2.57e-57 Blood protein levels; LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg00656387 chr3:40428638 ENTPD3 0.5 8.29 0.41 2.68e-15 Renal cell carcinoma; LIHC cis rs4638749 0.677 rs4676187 chr2:108842936 T/C cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs60871478 1.000 rs4720917 chr7:806998 C/G cg05535760 chr7:792225 HEATR2 0.79 11.27 0.52 2.85e-25 Cerebrospinal P-tau181p levels; LIHC cis rs6952808 0.929 rs2280548 chr7:1976667 G/T cg02951883 chr7:2050386 MAD1L1 -0.65 -10.33 -0.49 6.14e-22 Bipolar disorder and schizophrenia; LIHC cis rs67460515 0.531 rs1585483 chr3:160843111 G/A cg17135325 chr3:160939158 NMD3 0.54 7.62 0.38 2.49e-13 Parkinson's disease; LIHC cis rs16958440 0.581 rs56395942 chr18:44672299 G/T cg17192377 chr18:44677553 HDHD2 0.51 6.33 0.32 7.85e-10 Sitting height ratio; LIHC cis rs600806 0.815 rs3768495 chr1:109935325 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs4722404 0.502 rs13234017 chr7:3110587 C/A cg19214707 chr7:3157722 NA -0.34 -5.85 -0.3 1.13e-8 Atopic dermatitis; LIHC cis rs12200782 1.000 rs4515370 chr6:26625319 T/C cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19902697 chr11:76494208 TSKU 0.46 6.37 0.33 6.11e-10 Lung function (FEV1/FVC); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg14131272 chr14:39583276 SIP1 -0.45 -6.76 -0.34 6.12e-11 Hepatitis; LIHC trans rs637571 0.522 rs28578718 chr11:65748400 C/A cg17712092 chr4:129076599 LARP1B 0.74 13.11 0.58 4.39e-32 Eosinophil percentage of white cells; LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg12516959 chr21:47718080 NA 0.36 5.94 0.31 7.17e-9 Testicular germ cell tumor; LIHC cis rs9325144 0.505 rs10785560 chr12:38636622 C/T cg26384229 chr12:38710491 ALG10B 0.47 7.38 0.37 1.24e-12 Morning vs. evening chronotype; LIHC cis rs644799 0.544 rs56298021 chr11:95545113 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.64 9.27 0.45 2.13e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs1401999 1.000 rs939336 chr3:183685534 A/G cg05044414 chr3:183734942 ABCC5 0.35 6.17 0.32 1.97e-9 Anterior chamber depth; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11310629 chr13:45991975 SLC25A30 0.43 6.24 0.32 1.27e-9 Pancreatic cancer; LIHC cis rs644799 1.000 rs543530 chr11:95545170 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs3780486 0.846 rs10813954 chr9:33137596 A/C cg20290983 chr6:43655470 MRPS18A 1.19 30.89 0.86 5.55e-101 IgG glycosylation; LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.57 8.02 0.4 1.73e-14 Lymphocyte counts; LIHC cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.72 0.39 1.27e-13 Bipolar disorder; LIHC cis rs870825 0.929 rs2310102 chr4:185595141 C/G cg04058563 chr4:185651563 MLF1IP -0.73 -6.62 -0.34 1.42e-10 Blood protein levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19949018 chr17:2275913 SGSM2 -0.41 -6.28 -0.32 1.01e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4466137 0.830 rs10039752 chr5:82974532 G/A cg16102102 chr5:83017553 HAPLN1 -0.46 -7.35 -0.37 1.44e-12 Prostate cancer; LIHC cis rs2075371 0.932 rs2241332 chr7:133969439 A/G cg20476274 chr7:133979776 SLC35B4 0.72 9.71 0.46 7.65e-20 Mean platelet volume; LIHC cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg03264133 chr6:25882463 NA -0.63 -8.85 -0.43 4.88e-17 Blood metabolite levels; LIHC cis rs1048238 0.506 rs7525608 chr1:16141901 A/G cg00529422 chr1:16285251 ZBTB17 -0.32 -5.93 -0.31 7.31e-9 Systolic blood pressure; LIHC cis rs546131 0.642 rs12793173 chr11:34834204 T/C cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.59 -0.34 1.66e-10 Lung disease severity in cystic fibrosis; LIHC cis rs9457247 1.000 rs404222 chr6:167402150 G/A cg23791538 chr6:167370224 RNASET2 -0.57 -8.93 -0.43 2.76e-17 Crohn's disease; LIHC trans rs1005277 0.579 rs2021649 chr10:38392122 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1982963 1.000 rs2029975 chr14:52506070 C/T cg10843707 chr14:52510701 NID2 -0.44 -7.7 -0.38 1.51e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2404602 0.622 rs9635380 chr15:77103479 A/G cg03037974 chr15:76606532 NA -0.6 -9.88 -0.47 2.11e-20 Blood metabolite levels; LIHC cis rs2549003 1.000 rs2070725 chr5:131821788 C/T cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs1577917 1.000 rs13194429 chr6:86646705 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.3 -0.37 2.1e-12 Response to antipsychotic treatment; LIHC cis rs8177179 0.570 rs4441652 chr3:133439450 A/G cg24879335 chr3:133465180 TF 0.44 6.99 0.35 1.49e-11 Iron status biomarkers (transferrin levels); LIHC cis rs9388451 0.874 rs7739566 chr6:126094757 A/T cg05901451 chr6:126070800 HEY2 -0.76 -17.64 -0.69 5.3e-50 Brugada syndrome; LIHC cis rs4728302 0.869 rs13228262 chr7:133598288 A/G cg10665199 chr7:133106180 EXOC4 0.38 6.64 0.34 1.21e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs826838 0.967 rs7299170 chr12:38789536 G/A cg26384229 chr12:38710491 ALG10B 1.06 14.27 0.61 1.46e-36 Heart rate; LIHC cis rs77106637 0.932 rs3814730 chr11:72555553 G/A cg03713592 chr11:72463424 ARAP1 0.86 7.78 0.39 8.5e-14 Type 2 diabetes; LIHC cis rs921968 0.613 rs556497 chr2:219446477 G/A cg17980119 chr2:219472607 PLCD4 0.34 5.88 0.3 9.92e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg27170947 chr2:26402098 FAM59B -0.71 -8.65 -0.42 2.05e-16 Gut microbiome composition (summer); LIHC cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg13271783 chr10:134563150 INPP5A -0.6 -7.12 -0.36 6.33e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1816752 0.905 rs9511260 chr13:25011176 T/C cg02811702 chr13:24901961 NA 0.25 6.25 0.32 1.24e-9 Obesity-related traits; LIHC cis rs1475911 1.000 rs2839465 chr21:43511232 C/T cg19766460 chr21:43528205 UMODL1;C21orf128 0.69 9.96 0.47 1.09e-20 IgG glycosylation; LIHC cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg24250549 chr1:154909240 PMVK 0.64 9.8 0.47 3.74e-20 Prostate cancer; LIHC cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg11890956 chr21:40555474 PSMG1 1.07 16.04 0.66 1.47e-43 Cognitive function; LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs4665809 1.000 rs6546767 chr2:26328746 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.72 -0.43 1.26e-16 Gut microbiome composition (summer); LIHC cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs765787 0.530 rs1706837 chr15:45519036 A/G cg25801113 chr15:45476975 SHF 0.37 6.4 0.33 5.06e-10 Uric acid levels; LIHC cis rs6598955 0.724 rs7547520 chr1:26592310 C/T cg04990556 chr1:26633338 UBXN11 -0.62 -10.16 -0.48 2.37e-21 Obesity-related traits; LIHC cis rs2404602 0.692 rs4886503 chr15:77108874 C/T cg23625390 chr15:77176239 SCAPER -0.35 -5.79 -0.3 1.63e-8 Blood metabolite levels; LIHC cis rs10751667 0.580 rs7395515 chr11:1005160 C/T cg20946044 chr11:1010712 AP2A2 -0.33 -5.87 -0.3 1.04e-8 Alzheimer's disease (late onset); LIHC cis rs763121 0.925 rs5750654 chr22:39051428 T/C cg21395723 chr22:39101663 GTPBP1 0.38 6.45 0.33 3.75e-10 Menopause (age at onset); LIHC cis rs4742903 0.967 rs2122577 chr9:106866703 C/T cg14250997 chr9:106856677 SMC2 0.42 7.31 0.37 1.9e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2979489 0.945 rs17627903 chr8:30351812 T/C cg26383811 chr8:30366931 RBPMS -0.76 -12.29 -0.55 5.2e-29 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg18357526 chr6:26021779 HIST1H4A 0.43 6.45 0.33 3.81e-10 Height; LIHC cis rs1559088 0.847 rs3760891 chr19:33599708 C/T cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs875971 0.929 rs778712 chr7:65849978 C/T cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs17095355 1.000 rs11194941 chr10:111744810 A/G cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.84 -0.3 1.24e-8 Biliary atresia; LIHC cis rs12220238 0.554 rs10824192 chr10:76251573 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.7 6.39 0.33 5.51e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs72627123 0.867 rs61522544 chr14:74481953 G/A cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 6.02 0.31 4.61e-9 Morning vs. evening chronotype; LIHC trans rs916888 0.773 rs199533 chr17:44828931 G/A cg07870213 chr5:140052090 DND1 1.02 10.44 0.49 2.55e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg26939375 chr7:64535504 NA -0.47 -7.16 -0.36 4.97e-12 Aortic root size; LIHC cis rs1799949 0.929 rs799905 chr17:41277187 G/C cg25072359 chr17:41440525 NA 0.4 6.39 0.33 5.53e-10 Menopause (age at onset); LIHC cis rs9470366 0.527 rs4711456 chr6:36632482 C/T cg08179530 chr6:36648295 CDKN1A -0.59 -9.07 -0.44 9.36e-18 QRS duration; LIHC cis rs9902453 0.726 rs3115088 chr17:28031275 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 13.6 0.59 5.86e-34 Coffee consumption (cups per day); LIHC cis rs1023500 0.573 rs133370 chr22:42465260 T/C cg04733989 chr22:42467013 NAGA 0.66 9.61 0.46 1.62e-19 Schizophrenia; LIHC cis rs4660261 0.526 rs803680 chr1:44364370 G/C cg12908607 chr1:44402522 ARTN -0.49 -8.17 -0.4 6.18e-15 Intelligence (multi-trait analysis); LIHC cis rs8062405 0.755 rs62031607 chr16:28631530 A/T cg16576597 chr16:28551801 NUPR1 0.42 6.16 0.32 2.1e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11958404 0.932 rs6859470 chr5:157429505 T/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.11e-27 IgG glycosylation; LIHC cis rs12464559 0.826 rs78092271 chr2:152649909 G/C cg01189475 chr2:152685088 ARL5A -0.69 -6.55 -0.33 2.06e-10 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7666738 0.611 rs34982650 chr4:98819530 T/A cg05340658 chr4:99064831 C4orf37 0.63 11.49 0.53 4.74e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs1348850 0.914 rs4893950 chr2:178304885 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.89 14.17 0.61 3.6e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs743757 1.000 rs2236973 chr3:50474284 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.48 7.51 0.38 5.34e-13 Diastolic blood pressure; LIHC cis rs8180040 0.620 rs17784127 chr3:47061700 T/C cg16586182 chr3:47516702 SCAP 0.47 8.57 0.42 3.7e-16 Colorectal cancer; LIHC cis rs7945705 0.747 rs1980429 chr11:9010474 C/A cg12365402 chr11:9010492 NRIP3 -0.34 -8.7 -0.43 1.38e-16 Hemoglobin concentration; LIHC cis rs61863818 0.521 rs7923907 chr10:99143499 C/T cg06359132 chr10:99160096 RRP12 0.35 5.78 0.3 1.65e-8 Monocyte percentage of white cells; LIHC cis rs7945718 0.934 rs10831905 chr11:12776467 C/T cg25843174 chr11:12811716 TEAD1 -0.28 -6.53 -0.33 2.37e-10 Educational attainment (years of education); LIHC cis rs57590327 0.503 rs7631052 chr3:81866235 C/A cg07356753 chr3:81810745 GBE1 -0.51 -7.93 -0.39 3.05e-14 Extraversion; LIHC cis rs11252926 0.605 rs10904075 chr10:425667 A/G cg16346588 chr10:242978 ZMYND11 -0.49 -5.79 -0.3 1.61e-8 Psychosis in Alzheimer's disease; LIHC cis rs7537052 0.564 rs6669395 chr1:36653717 A/G cg24686825 chr1:36642396 MAP7D1 -0.44 -8.22 -0.41 4.36e-15 Schizophrenia; LIHC cis rs400736 0.859 rs379920 chr1:8028865 G/C cg25007680 chr1:8021821 PARK7 0.61 9.79 0.47 4.16e-20 Response to antidepressants and depression; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01809819 chr1:31192165 MATN1 0.38 6.32 0.32 8.17e-10 Cognitive function; LIHC cis rs11053548 0.602 rs11053554 chr12:10175667 G/A cg04314261 chr12:10163030 CLEC12B 0.39 6.16 0.32 1.99e-9 Systolic blood pressure in sickle cell anemia; LIHC cis rs6752107 0.837 rs3792108 chr2:234184952 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.24 0.41 3.62e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2180341 0.814 rs6940933 chr6:127732740 C/G cg27446573 chr6:127587934 RNF146 0.78 12.75 0.57 1.02e-30 Breast cancer; LIHC cis rs35110281 0.712 rs162345 chr21:44954155 T/G cg01579765 chr21:45077557 HSF2BP -0.3 -5.73 -0.3 2.15e-8 Mean corpuscular volume; LIHC cis rs722599 0.683 rs2302834 chr14:75279395 T/A cg11812906 chr14:75593930 NEK9 0.42 6.47 0.33 3.47e-10 IgG glycosylation; LIHC trans rs2749592 0.550 rs7081464 chr10:37883937 C/T cg23533926 chr12:111358616 MYL2 0.31 6.05 0.31 3.88e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7616330 0.836 rs6780338 chr3:71029408 C/T cg01511742 chr3:71112437 FOXP1 0.41 5.83 0.3 1.29e-8 QT interval; LIHC cis rs11792861 0.816 rs2304779 chr9:111670513 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.62 -8.98 -0.44 1.85e-17 Menarche (age at onset); LIHC trans rs4906332 1.000 rs2065015 chr14:103904061 G/T cg17675199 chr6:35436792 RPL10A -0.32 -6.34 -0.32 7.25e-10 Coronary artery disease; LIHC cis rs875971 0.861 rs801215 chr7:66011938 A/T cg18252515 chr7:66147081 NA 0.46 6.81 0.35 4.41e-11 Aortic root size; LIHC trans rs1814175 0.645 rs847632 chr11:49926097 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -19.79 -0.73 1.21e-58 Height; LIHC cis rs7078219 0.505 rs7916751 chr10:101285650 T/A cg06854084 chr10:101292507 NKX2-3 -0.32 -5.89 -0.3 9.25e-9 Dental caries; LIHC cis rs6449957 0.832 rs7715780 chr5:67453288 A/G cg23036683 chr5:67512108 NA 0.41 5.85 0.3 1.13e-8 Cleft lip with or without cleft palate; LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs7762018 0.607 rs6907814 chr6:170058206 G/A cg19338460 chr6:170058176 WDR27 -0.89 -9.83 -0.47 3.11e-20 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6424115 0.931 rs2473377 chr1:24148260 T/C cg15997130 chr1:24165203 NA 0.47 9.51 0.46 3.53e-19 Immature fraction of reticulocytes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20982606 chr12:109535391 UNG -0.51 -7.66 -0.38 1.89e-13 Cognitive function; LIHC trans rs2727020 0.658 rs10839278 chr11:49450847 G/C cg03929089 chr4:120376271 NA -0.85 -16.45 -0.66 3.43e-45 Coronary artery disease; LIHC cis rs875971 0.862 rs6460302 chr7:65960257 C/G cg18252515 chr7:66147081 NA -0.42 -5.93 -0.31 7.22e-9 Aortic root size; LIHC cis rs35110281 0.743 rs2329443 chr21:45059431 C/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.59 -0.34 1.7e-10 Mean corpuscular volume; LIHC cis rs11229555 0.645 rs11229428 chr11:58180382 C/T cg15696309 chr11:58395628 NA -0.66 -7.75 -0.39 1.06e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs539514 0.690 rs607095 chr13:76316165 A/T cg04757411 chr13:76259545 LMO7 -0.47 -8.18 -0.4 5.52e-15 Type 1 diabetes; LIHC cis rs870825 0.929 rs871254 chr4:185589226 G/C cg04058563 chr4:185651563 MLF1IP 0.75 6.01 0.31 4.86e-9 Blood protein levels; LIHC cis rs12594515 1.000 rs6493168 chr15:45986811 A/C cg06207120 chr15:45996521 NA 0.34 6.62 0.34 1.39e-10 Waist circumference;Weight; LIHC cis rs1062177 1.000 rs2915878 chr5:151149662 A/G cg00977110 chr5:151150581 G3BP1 0.56 7.11 0.36 6.8e-12 Preschool internalizing problems; LIHC cis rs875971 0.964 rs11765965 chr7:65842221 A/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs9325144 0.647 rs12427164 chr12:38868777 A/G cg26384229 chr12:38710491 ALG10B -0.56 -7.55 -0.38 4.12e-13 Morning vs. evening chronotype; LIHC cis rs9543976 0.920 rs9543972 chr13:76121675 T/C cg01531495 chr13:76123901 UCHL3 0.52 6.14 0.31 2.32e-9 Diabetic retinopathy; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.71 0.38 1.35e-13 Prudent dietary pattern; LIHC trans rs11088226 0.581 rs2016103 chr21:33878030 G/A cg09050820 chr6:167586206 TCP10L2 0.5 7.83 0.39 6.22e-14 Gastritis; LIHC cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 6.9 0.35 2.53e-11 Bipolar disorder; LIHC cis rs1728785 0.818 rs12926059 chr16:68569459 T/C cg02972257 chr16:68554789 NA -0.52 -6.11 -0.31 2.79e-9 Ulcerative colitis; LIHC cis rs965469 0.895 rs12626130 chr20:3393192 G/T cg25506879 chr20:3388711 C20orf194 -0.51 -5.84 -0.3 1.2e-8 IFN-related cytopenia; LIHC cis rs7100689 0.646 rs10466235 chr10:82149655 C/T cg00277334 chr10:82204260 NA 0.43 6.33 0.32 7.86e-10 Post bronchodilator FEV1; LIHC trans rs7395662 0.525 rs4882060 chr11:48441874 G/C cg15704280 chr7:45808275 SEPT13 -0.42 -6.44 -0.33 3.98e-10 HDL cholesterol; LIHC cis rs7772486 0.790 rs3924499 chr6:146232978 A/T cg13319975 chr6:146136371 FBXO30 0.39 6.31 0.32 8.81e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg13152130 chr6:118910203 C6orf204 -0.65 -7.34 -0.37 1.61e-12 Diastolic blood pressure; LIHC cis rs9309711 0.961 rs11675119 chr2:3476422 C/A cg10845886 chr2:3471009 TTC15 -0.63 -12.12 -0.55 2.26e-28 Neurofibrillary tangles; LIHC cis rs67478160 0.529 rs12880413 chr14:104267407 A/G cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs10832963 0.924 rs10500834 chr11:18638712 A/T cg20219074 chr11:18656078 SPTY2D1 0.84 13.99 0.6 1.74e-35 Breast cancer; LIHC trans rs3783890 0.943 rs11628518 chr14:93746667 C/T cg02802420 chr16:69363236 PDF;COG8 0.32 6.22 0.32 1.44e-9 Body mass index; LIHC cis rs1059312 0.808 rs10847694 chr12:129292457 C/A cg09035930 chr12:129282057 SLC15A4 0.6 11.23 0.52 4.14e-25 Systemic lupus erythematosus; LIHC cis rs78456975 1.000 rs72778004 chr2:1571892 T/A cg01028140 chr2:1542097 TPO -0.48 -5.89 -0.3 9.04e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2404602 0.692 rs4360890 chr15:77173295 G/A cg03037974 chr15:76606532 NA 0.73 14.44 0.62 3.04e-37 Blood metabolite levels; LIHC cis rs4713118 0.824 rs9468223 chr6:27740666 C/T cg20933634 chr6:27740509 NA 0.46 6.09 0.31 3.08e-9 Parkinson's disease; LIHC cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg14004847 chr7:1930337 MAD1L1 -0.43 -6.12 -0.31 2.52e-9 Bipolar disorder and schizophrenia; LIHC cis rs9640161 0.830 rs17173681 chr7:150059414 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 0.47 8.38 0.41 1.4e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs12586317 0.534 rs28384418 chr14:35452126 C/A cg26967526 chr14:35346199 BAZ1A -0.36 -5.71 -0.3 2.43e-8 Psoriasis; LIHC cis rs11030122 0.702 rs10835406 chr11:3992954 G/T cg18678763 chr11:4115507 RRM1 0.54 7.97 0.4 2.43e-14 Mean platelet volume;Platelet distribution width; LIHC cis rs769267 0.929 rs34538000 chr19:19481379 G/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.01 -0.31 4.78e-9 Tonsillectomy; LIHC cis rs986417 0.818 rs7153263 chr14:61099261 G/A cg27398547 chr14:60952738 C14orf39 0.67 7.41 0.37 1.03e-12 Gut microbiota (bacterial taxa); LIHC cis rs1552244 0.688 rs7645137 chr3:10020549 A/AT cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.67 0.5 4.02e-23 Alzheimer's disease; LIHC cis rs2732480 0.500 rs11168468 chr12:48612465 C/T cg21466736 chr12:48725269 NA -0.7 -10.78 -0.5 1.59e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs3796352 1.000 rs35507120 chr3:53053924 C/T cg07884673 chr3:53033167 SFMBT1 0.95 6.86 0.35 3.21e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs17331151 0.573 rs2240916 chr3:52859212 T/A cg04865290 chr3:52927548 TMEM110 -0.44 -6.35 -0.32 6.71e-10 Immune reponse to smallpox (secreted IL-2); LIHC trans rs1499614 0.522 rs13247442 chr7:66188858 T/C cg07424592 chr7:64974309 NA 0.78 7.27 0.37 2.44e-12 Gout; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg00593699 chr11:472782 PTDSS2 0.61 6.42 0.33 4.52e-10 Mean platelet volume; LIHC cis rs7246657 0.943 rs3745765 chr19:37854235 G/T cg23950597 chr19:37808831 NA -0.43 -5.73 -0.3 2.16e-8 Coronary artery calcification; LIHC cis rs6570726 0.902 rs973855 chr6:145781850 C/T cg23711669 chr6:146136114 FBXO30 -0.47 -8.24 -0.41 3.65e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02160872 chr5:212506 CCDC127 0.48 6.19 0.32 1.72e-9 Hepatitis; LIHC cis rs1707322 1.000 rs12077546 chr1:46431806 C/T cg03146154 chr1:46216737 IPP 0.47 7.73 0.39 1.21e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9296092 0.538 rs3916674 chr6:33522975 C/T cg13560919 chr6:33536144 NA -0.39 -6.31 -0.32 8.5e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs61931739 0.500 rs34418276 chr12:34535976 C/T cg26384229 chr12:38710491 ALG10B 0.78 9.5 0.46 3.78e-19 Morning vs. evening chronotype; LIHC cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg18404041 chr3:52824283 ITIH1 -0.52 -8.3 -0.41 2.52e-15 Bipolar disorder; LIHC cis rs798766 1.000 rs1665364 chr4:1727206 A/G cg21231739 chr4:1642635 FAM53A 0.36 5.76 0.3 1.89e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs3924048 0.559 rs4075304 chr1:12626803 C/T cg00291366 chr1:12616550 NA 0.38 7.83 0.39 6.11e-14 Optic cup area; LIHC cis rs67460515 0.892 rs11929238 chr3:161045937 A/T cg17135325 chr3:160939158 NMD3 0.57 8.13 0.4 7.9e-15 Parkinson's disease; LIHC cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs780094 0.564 rs4665978 chr2:27648726 T/C cg27432699 chr2:27873401 GPN1 -0.43 -6.03 -0.31 4.25e-9 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs10540 1.000 rs12419766 chr11:503710 C/T cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.15e-11 Body mass index; LIHC cis rs9420 0.961 rs12805841 chr11:57443842 G/A cg19752551 chr11:57585705 CTNND1 -0.53 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs2153535 0.580 rs4960423 chr6:8477210 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs1712517 0.873 rs7916056 chr10:104997914 T/C cg05636881 chr10:105038444 INA -0.4 -6.3 -0.32 8.95e-10 Migraine; LIHC cis rs6586163 1.000 rs6586163 chr10:90752018 A/C cg03111039 chr10:90751583 FAS;ACTA2 -0.57 -8.24 -0.41 3.65e-15 Chronic lymphocytic leukemia; LIHC cis rs1385374 0.858 rs34888374 chr12:129296536 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.75 0.39 1.09e-13 Systemic lupus erythematosus; LIHC cis rs6089584 1.000 rs6089583 chr20:60563624 G/A cg13770153 chr20:60521292 NA -0.35 -6.9 -0.35 2.53e-11 Body mass index; LIHC trans rs6952808 0.689 rs58227534 chr7:2046328 A/G cg04565464 chr8:145669602 NFKBIL2 0.38 6.27 0.32 1.1e-9 Bipolar disorder and schizophrenia; LIHC cis rs798554 0.679 rs2266922 chr7:2824707 G/A cg19717773 chr7:2847554 GNA12 -0.41 -7.36 -0.37 1.4e-12 Height; LIHC cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg22633049 chr21:46681294 NA -0.37 -6.43 -0.33 4.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg06238570 chr21:40685208 BRWD1 0.61 7.25 0.36 2.84e-12 Cognitive function; LIHC cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs11583043 1.000 rs12567858 chr1:101517688 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.08 0.4 1.12e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1008375 0.686 rs34338142 chr4:17626174 T/A cg16339924 chr4:17578868 LAP3 0.42 5.99 0.31 5.35e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10131894 0.611 rs175000 chr14:75436367 T/C cg11812906 chr14:75593930 NEK9 -0.65 -11.57 -0.53 2.47e-26 Coronary artery disease; LIHC cis rs6542838 0.704 rs13011428 chr2:99528305 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.42 -6.07 -0.31 3.45e-9 Fear of minor pain; LIHC cis rs936229 0.861 rs3935077 chr15:75120211 C/G cg14664628 chr15:75095509 CSK -1.02 -19.85 -0.73 7.14e-59 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs7945718 0.621 rs11022465 chr11:12686139 C/T cg25843174 chr11:12811716 TEAD1 -0.32 -7.51 -0.38 5.18e-13 Educational attainment (years of education); LIHC cis rs77106637 0.860 rs1552224 chr11:72433098 A/C cg03878208 chr11:72483293 STARD10 0.63 5.76 0.3 1.83e-8 Type 2 diabetes; LIHC cis rs1816752 0.905 rs9581026 chr13:24997926 C/A cg02811702 chr13:24901961 NA 0.25 6.17 0.32 1.96e-9 Obesity-related traits; LIHC cis rs992157 0.796 rs55680399 chr2:219160621 T/C cg00012203 chr2:219082015 ARPC2 0.85 13.91 0.6 3.46e-35 Colorectal cancer; LIHC cis rs909341 0.909 rs1151623 chr20:62368606 T/C cg03999872 chr20:62272968 STMN3 0.42 6.25 0.32 1.25e-9 Atopic dermatitis; LIHC cis rs864537 0.646 rs1723016 chr1:167433056 T/C cg22356347 chr1:167427500 CD247 -0.34 -5.81 -0.3 1.45e-8 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs7617480 0.648 rs6766238 chr3:48801929 G/A cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.45 0.33 3.76e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg03060546 chr3:49711283 APEH 0.48 7.36 0.37 1.37e-12 Parkinson's disease; LIHC cis rs56235845 0.694 rs4976643 chr5:176760227 A/C cg06060754 chr5:176797920 RGS14 0.47 6.59 0.34 1.62e-10 Hemoglobin concentration;Hematocrit; LIHC cis rs2717559 0.542 rs10956986 chr8:143886601 C/T cg06565975 chr8:143823917 SLURP1 -0.38 -6.51 -0.33 2.66e-10 Urinary tract infection frequency; LIHC cis rs3106136 1.000 rs2632401 chr4:95147055 C/G cg11021082 chr4:95130006 SMARCAD1 0.41 7.62 0.38 2.52e-13 Capecitabine sensitivity; LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg15586393 chr4:1244086 CTBP1;C4orf42 0.41 5.75 0.3 2.02e-8 Longevity; LIHC cis rs1943345 0.642 rs11233500 chr11:82881407 C/T cg07047830 chr11:82868014 PCF11 -0.55 -9.55 -0.46 2.56e-19 Obesity-related traits; LIHC cis rs6701037 0.782 rs12760073 chr1:175139295 G/T cg17845761 chr1:175162550 KIAA0040 -0.43 -7.0 -0.35 1.37e-11 Alcohol dependence; LIHC cis rs868036 0.681 rs13329582 chr15:68104608 G/C cg24579218 chr15:68104479 NA -0.34 -5.77 -0.3 1.81e-8 Restless legs syndrome; LIHC cis rs7619427 0.544 rs9809968 chr3:44042297 A/T cg24966902 chr3:44043705 NA 0.53 8.19 0.41 5.14e-15 Schizophrenia; LIHC cis rs6582630 0.555 rs10880602 chr12:38505660 T/C cg13010199 chr12:38710504 ALG10B 0.44 6.17 0.32 1.96e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs6461049 0.519 rs3778992 chr7:2175313 C/G cg21782813 chr7:2030301 MAD1L1 0.38 6.53 0.33 2.37e-10 Schizophrenia; LIHC cis rs941873 0.836 rs6480931 chr10:81108482 T/C cg11057378 chr10:81107060 PPIF 0.36 5.76 0.3 1.89e-8 Height; LIHC cis rs4808199 1.000 rs4808199 chr19:19545099 C/T cg21559469 chr19:19431446 KIAA0892;SF4 0.46 5.96 0.31 6.3e-9 Nonalcoholic fatty liver disease; LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.04 -0.31 4.06e-9 Total body bone mineral density; LIHC cis rs7772486 0.720 rs4896837 chr6:146014168 C/T cg13319975 chr6:146136371 FBXO30 0.4 6.46 0.33 3.65e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs311392 0.554 rs395449 chr8:55100391 A/G cg20636351 chr8:55087400 NA -0.35 -7.27 -0.37 2.47e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs7937682 0.632 rs2070894 chr11:111780837 G/A cg09085632 chr11:111637200 PPP2R1B 0.92 13.39 0.59 3.72e-33 Primary sclerosing cholangitis; LIHC cis rs2361718 0.500 rs8064429 chr17:78096187 A/C cg09238746 chr17:78121135 EIF4A3 -0.62 -9.69 -0.46 9.19e-20 Yeast infection; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg01799338 chr1:36348937 EIF2C1 -0.41 -6.51 -0.33 2.71e-10 Triglycerides; LIHC cis rs13191362 1.000 rs36007635 chr6:163009335 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6918586 0.658 rs198856 chr6:26102708 G/A cg18357526 chr6:26021779 HIST1H4A -0.56 -8.3 -0.41 2.45e-15 Schizophrenia; LIHC cis rs5753618 0.561 rs714909 chr22:31741067 G/A cg22777020 chr22:31556080 RNF185 0.56 6.4 0.33 4.98e-10 Colorectal cancer; LIHC trans rs6600671 1.000 rs12145080 chr1:121185531 C/T cg09829573 chr1:144692074 NBPF9 0.43 7.78 0.39 8.39e-14 Hip geometry; LIHC cis rs74544699 1.000 rs529312 chr4:74767982 A/T cg02530824 chr4:74847766 PF4 0.61 6.34 0.32 7.16e-10 Growth-regulated protein alpha levels; LIHC trans rs10242455 0.702 rs3528 chr7:99055940 T/C cg09045935 chr12:6379348 NA 0.83 6.85 0.35 3.36e-11 Blood metabolite levels; LIHC cis rs7927592 0.956 rs11228258 chr11:68254328 A/C cg20283391 chr11:68216788 NA 0.49 7.35 0.37 1.48e-12 Total body bone mineral density; LIHC cis rs875971 0.964 rs6945032 chr7:65922486 C/T cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg15320075 chr8:145703422 NA -0.56 -9.77 -0.47 4.72e-20 Age at first birth; LIHC cis rs7520050 0.931 rs35743647 chr1:46407252 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.42 6.19 0.32 1.71e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2073499 0.872 rs2282751 chr3:50291785 A/G cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.81 -11.23 -0.52 4e-25 Schizophrenia; LIHC cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg07061783 chr6:25882402 NA -0.44 -6.16 -0.32 2.06e-9 Blood metabolite levels; LIHC cis rs8017423 0.967 rs7150093 chr14:90724661 C/T cg14092571 chr14:90743983 NA 0.38 6.03 0.31 4.36e-9 Mortality in heart failure; LIHC cis rs2066819 1.000 rs41363748 chr12:56696056 C/T cg26734620 chr12:56694298 CS -1.26 -11.0 -0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs9814567 1.000 rs1814336 chr3:134200823 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.3 -0.55 4.7e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00510787 chr6:151772946 C6orf211;RMND1 0.43 6.18 0.32 1.78e-9 Cognitive function; LIHC cis rs4843747 0.671 rs13334603 chr16:88116016 T/C cg07560587 chr16:88016574 BANP 0.35 5.82 0.3 1.39e-8 Menopause (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12944146 chr22:50725609 PLXNB2 0.44 6.8 0.35 4.77e-11 Longevity; LIHC cis rs1707322 1.000 rs946524 chr1:46487560 A/G cg06784218 chr1:46089804 CCDC17 -0.36 -6.47 -0.33 3.33e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.28 -5.82 -0.3 1.33e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs17152411 1.000 rs61873277 chr10:126619331 C/A cg07906193 chr10:126599966 NA 0.47 7.36 0.37 1.34e-12 Height; LIHC cis rs9596863 0.898 rs9591534 chr13:54363861 C/G ch.13.53330881F chr13:54432880 NA 0.42 5.77 0.3 1.75e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs6691722 0.503 rs6656485 chr1:24707685 A/G cg18323236 chr1:24743029 NIPAL3 0.41 7.37 0.37 1.29e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs2153535 0.580 rs1335633 chr6:8448800 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.84e-10 Diabetic kidney disease; LIHC cis rs8062405 0.754 rs28410083 chr16:28631360 A/T cg00204512 chr16:28754710 NA -0.38 -6.3 -0.32 9.25e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs910316 0.839 rs35977276 chr14:75637359 A/C cg08847533 chr14:75593920 NEK9 -0.88 -18.83 -0.71 8.98e-55 Height; LIHC cis rs2732480 0.557 rs2732441 chr12:48723324 C/G cg21466736 chr12:48725269 NA -0.73 -11.35 -0.52 1.54e-25 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs12291225 0.679 rs1043237 chr11:14289053 A/T cg05501817 chr11:14380813 RRAS2 -0.42 -5.73 -0.3 2.16e-8 Sense of smell; LIHC cis rs6456156 0.792 rs2039321 chr6:167516299 C/T cg07741184 chr6:167504864 NA 0.26 6.34 0.32 7.27e-10 Primary biliary cholangitis; LIHC cis rs2197308 0.610 rs10880837 chr12:37864924 C/T cg26384229 chr12:38710491 ALG10B 0.82 10.19 0.48 1.8e-21 Morning vs. evening chronotype; LIHC cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs8081692 1 rs8081692 chr17:38154595 A/G cg17467752 chr17:38218738 THRA 0.76 13.96 0.6 2.26e-35 Neutrophil count; LIHC cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -12.63 -0.56 2.81e-30 Alzheimer's disease; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.520 rs12621007 chr2:99791946 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.24 24.53 0.8 2.3e-77 Chronic sinus infection; LIHC cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg04317338 chr11:64019027 PLCB3 -0.88 -11.02 -0.51 2.31e-24 Mean platelet volume; LIHC cis rs722599 0.683 rs7142898 chr14:75254310 A/T cg11812906 chr14:75593930 NEK9 0.43 6.45 0.33 3.75e-10 IgG glycosylation; LIHC cis rs12980942 0.591 rs1946613 chr19:41767785 C/T cg25627403 chr19:41769009 HNRNPUL1 0.58 7.04 0.36 1.03e-11 Coronary artery disease; LIHC cis rs875971 1.000 rs10215948 chr7:65747786 G/A cg18876405 chr7:65276391 NA -0.37 -6.74 -0.34 6.67e-11 Aortic root size; LIHC cis rs60871478 0.636 rs12532761 chr7:905229 C/T cg05535760 chr7:792225 HEATR2 -0.81 -6.58 -0.34 1.77e-10 Cerebrospinal P-tau181p levels; LIHC cis rs7412746 0.634 rs4451553 chr1:150937329 C/T cg17724175 chr1:150552817 MCL1 0.43 8.21 0.41 4.48e-15 Melanoma; LIHC cis rs9560113 1.000 rs9555806 chr13:112179954 G/A cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs7188697 0.922 rs9926577 chr16:58613431 C/T cg02549819 chr16:58548995 SETD6 0.48 7.62 0.38 2.52e-13 QT interval; LIHC cis rs2228479 0.850 rs12596934 chr16:89841605 T/G cg06558623 chr16:89946397 TCF25 0.84 11.74 0.54 5.79e-27 Skin colour saturation; LIHC cis rs4450131 0.900 rs11245333 chr10:126383088 C/A cg20435097 chr10:126320824 FAM53B 0.52 9.26 0.45 2.24e-18 White blood cell count (basophil); LIHC cis rs6733011 0.508 rs13004700 chr2:99527568 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -6.97 -0.35 1.63e-11 Bipolar disorder; LIHC trans rs78049276 0.736 rs73855810 chr4:148383424 G/A cg13149281 chr14:23389818 RBM23;PRMT5 -0.59 -7.62 -0.38 2.46e-13 Pulse pressure; LIHC cis rs875971 0.528 rs801213 chr7:66014918 C/T cg11764359 chr7:65958608 NA -0.61 -8.83 -0.43 5.48e-17 Aortic root size; LIHC cis rs875971 1.000 rs2087647 chr7:65593188 C/A cg11764359 chr7:65958608 NA -0.87 -15.19 -0.63 3.51e-40 Aortic root size; LIHC cis rs311392 0.584 rs388075 chr8:55099893 T/C cg20636351 chr8:55087400 NA -0.35 -7.27 -0.37 2.47e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs7552404 0.960 rs4949877 chr1:76201668 C/G cg03433033 chr1:76189801 ACADM 0.63 8.86 0.43 4.44e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9768139 0.935 rs6953748 chr7:158121184 G/A cg25566285 chr7:158114605 PTPRN2 -0.26 -7.56 -0.38 3.76e-13 Calcium levels; LIHC trans rs8073060 0.963 rs35614987 chr17:33869466 A/C cg19694781 chr19:47549865 TMEM160 0.63 6.65 0.34 1.19e-10 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs12887734 0.569 rs66953418 chr14:104271470 G/A cg24130564 chr14:104152367 KLC1 -0.43 -7.06 -0.36 9.56e-12 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs9910055 0.529 rs228749 chr17:42174570 A/G cg19774624 chr17:42201019 HDAC5 0.5 5.96 0.31 6.28e-9 Total body bone mineral density; LIHC cis rs6060717 0.654 rs6058347 chr20:34483781 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -7.58 -0.38 3.34e-13 Hip circumference adjusted for BMI; LIHC cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg08888203 chr3:10149979 C3orf24 0.56 6.39 0.33 5.49e-10 Alzheimer's disease; LIHC cis rs4975709 0.531 rs6884044 chr5:1871599 C/T cg15595755 chr5:1867978 NA 0.4 8.11 0.4 8.87e-15 Cardiovascular disease risk factors; LIHC trans rs916888 0.610 rs199442 chr17:44820122 G/A cg22968622 chr17:43663579 NA 0.49 7.17 0.36 4.77e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7188697 0.922 rs246196 chr16:58574253 T/C cg02549819 chr16:58548995 SETD6 -0.45 -7.18 -0.36 4.43e-12 QT interval; LIHC cis rs3806843 0.868 rs2262574 chr5:140123635 G/T cg19875535 chr5:140030758 IK -0.36 -5.98 -0.31 5.68e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7474896 0.559 rs1779075 chr10:38167530 C/G cg25427524 chr10:38739819 LOC399744 0.47 5.95 0.31 6.6e-9 Obesity (extreme); LIHC cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.3 -0.45 1.65e-18 Bipolar disorder; LIHC cis rs6547741 0.935 rs6761095 chr2:27778010 G/T cg27432699 chr2:27873401 GPN1 0.7 11.6 0.53 1.82e-26 Oral cavity cancer; LIHC cis rs9733 0.621 rs6669122 chr1:150591732 A/G cg17724175 chr1:150552817 MCL1 -0.37 -7.47 -0.37 6.94e-13 Tonsillectomy; LIHC cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg06634786 chr22:41940651 POLR3H -0.76 -7.8 -0.39 7.67e-14 Vitiligo; LIHC cis rs3862030 0.720 rs7342070 chr10:104223628 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -7.31 -0.37 1.96e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg18252515 chr7:66147081 NA -1.32 -16.27 -0.66 1.7e-44 Diabetic kidney disease; LIHC cis rs12579753 1.000 rs2400979 chr12:82197353 T/C cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs4742903 0.967 rs7048372 chr9:106859738 T/C cg14250997 chr9:106856677 SMC2 0.43 7.55 0.38 3.9e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6942756 0.955 rs2056694 chr7:128923817 C/T cg02491457 chr7:128862824 NA -0.64 -9.16 -0.44 5.03e-18 White matter hyperintensity burden; LIHC cis rs9430161 0.645 rs12081186 chr1:11034195 T/C cg27631724 chr1:11040367 C1orf127 0.37 6.83 0.35 4.01e-11 Ewing sarcoma; LIHC cis rs2404602 0.967 rs7174096 chr15:77072400 A/G cg03037974 chr15:76606532 NA 0.72 13.91 0.6 3.6e-35 Blood metabolite levels; LIHC cis rs2933343 1.000 rs876756 chr3:128627623 G/A cg25356066 chr3:128598488 ACAD9 0.53 7.0 0.35 1.39e-11 IgG glycosylation; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg05896524 chr21:47604654 C21orf56 0.48 7.47 0.37 6.96e-13 Testicular germ cell tumor; LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.58 10.9 0.51 5.85e-24 Prudent dietary pattern; LIHC cis rs2574704 0.851 rs2574719 chr3:11660688 G/A cg15876825 chr3:11651881 VGLL4 0.49 7.9 0.39 3.85e-14 Body mass index; LIHC cis rs918629 0.716 rs3756703 chr5:95276063 G/A cg10483112 chr5:95245456 ELL2 -0.35 -5.9 -0.3 8.71e-9 IgG glycosylation; LIHC cis rs1005277 0.522 rs289650 chr10:37975505 G/T cg25427524 chr10:38739819 LOC399744 -0.58 -11.49 -0.53 4.63e-26 Extrinsic epigenetic age acceleration; LIHC cis rs7107174 0.901 rs901105 chr11:77924607 A/C cg02023728 chr11:77925099 USP35 0.52 9.68 0.46 9.7e-20 Testicular germ cell tumor; LIHC cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.72 -0.3 2.37e-8 Colorectal cancer; LIHC cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg06481639 chr22:41940642 POLR3H 0.66 6.95 0.35 1.9e-11 Vitiligo; LIHC cis rs17685 0.712 rs4552844 chr7:75718095 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1499614 1.000 rs1882655 chr7:66147057 T/C cg10756647 chr7:56101905 PSPH -0.98 -11.62 -0.53 1.57e-26 Gout; LIHC cis rs8180040 0.553 rs7620997 chr3:47214122 C/T cg27129171 chr3:47204927 SETD2 -0.55 -8.81 -0.43 6.49e-17 Colorectal cancer; LIHC cis rs9916302 0.904 rs4794814 chr17:37696852 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.37 -0.59 4.35e-33 Glomerular filtration rate (creatinine); LIHC cis rs9549367 0.756 rs9603814 chr13:113900782 C/T cg00898013 chr13:113819073 PROZ 0.32 5.99 0.31 5.26e-9 Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08007990 chr2:231276624 NA 0.45 6.4 0.33 5.16e-10 Lung function (FEV1/FVC); LIHC cis rs1801251 0.835 rs1446310 chr2:233683245 G/C cg08000102 chr2:233561755 GIGYF2 -0.74 -10.71 -0.5 2.79e-23 Coronary artery disease; LIHC cis rs6964587 1.000 rs6967256 chr7:91643219 G/A cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg07424592 chr7:64974309 NA 0.8 9.08 0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs4728302 0.869 rs7792905 chr7:133595602 G/T cg10665199 chr7:133106180 EXOC4 0.37 6.54 0.33 2.24e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7039377 0.554 rs7873962 chr9:38673606 T/G cg14625731 chr9:38672608 NA -0.47 -7.57 -0.38 3.55e-13 Obesity-related traits; LIHC cis rs9611565 0.592 rs12484254 chr22:41962003 T/A cg06634786 chr22:41940651 POLR3H -0.58 -6.29 -0.32 9.81e-10 Vitiligo; LIHC cis rs10751667 0.621 rs11246345 chr11:934924 T/C cg11406765 chr11:980039 AP2A2 -0.35 -5.78 -0.3 1.69e-8 Alzheimer's disease (late onset); LIHC cis rs4820294 0.669 rs12628135 chr22:38065655 A/G cg10587741 chr22:38071170 LGALS1 0.43 7.65 0.38 2.1e-13 Fat distribution (HIV); LIHC cis rs9470366 0.816 rs7774130 chr6:36623756 C/T cg08179530 chr6:36648295 CDKN1A 0.55 6.75 0.34 6.34e-11 QRS duration; LIHC cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.5 0.46 3.78e-19 Bipolar disorder; LIHC cis rs9733 0.596 rs72702536 chr1:150662574 C/T cg18016565 chr1:150552671 MCL1 0.59 11.59 0.53 2.02e-26 Tonsillectomy; LIHC cis rs72829446 0.530 rs7210292 chr17:7380305 G/T cg02795151 chr17:7402630 POLR2A 0.54 5.87 0.3 1.01e-8 Androgen levels; LIHC cis rs6933660 0.800 rs963193 chr6:151789355 G/T cg02564969 chr6:151773285 C6orf211;RMND1 -0.43 -6.12 -0.31 2.53e-9 Menarche (age at onset); LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg07234388 chr1:156261841 TMEM79 0.52 9.28 0.45 2.01e-18 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9534288 0.659 rs1581846 chr13:46650686 G/A cg15192986 chr13:46630673 CPB2 -0.43 -6.31 -0.32 8.51e-10 Blood protein levels; LIHC cis rs2228479 0.850 rs17227263 chr16:89810598 G/A cg19635926 chr16:89946313 TCF25 0.49 6.24 0.32 1.28e-9 Skin colour saturation; LIHC cis rs11676348 0.811 rs4674255 chr2:218987325 C/T cg00012203 chr2:219082015 ARPC2 -0.55 -7.78 -0.39 8.65e-14 Ulcerative colitis; LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg10150615 chr22:24372951 LOC391322 -0.47 -6.29 -0.32 9.65e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2243480 0.901 rs34807232 chr7:65965133 G/A cg12463550 chr7:65579703 CRCP 0.65 6.76 0.34 5.98e-11 Diabetic kidney disease; LIHC cis rs9296092 0.538 rs56205713 chr6:33517510 A/G cg13560919 chr6:33536144 NA -0.38 -6.36 -0.33 6.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg11070056 chr1:107600091 PRMT6 -0.71 -12.16 -0.55 1.64e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs477895 1.000 rs12785488 chr11:64107521 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.75 6.67 0.34 1.01e-10 Mean platelet volume; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg01339444 chr6:118972232 C6orf204 0.59 5.93 0.31 7.53e-9 Diastolic blood pressure; LIHC cis rs909341 0.537 rs6011098 chr20:62398935 C/T cg14758556 chr20:62440591 NA -0.46 -7.24 -0.36 2.95e-12 Atopic dermatitis; LIHC cis rs12291225 0.679 rs11023170 chr11:14294909 A/G cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.18e-31 Sense of smell; LIHC cis rs11212260 0.573 rs71488249 chr11:107162752 A/G cg25435332 chr11:107328525 CWF19L2 0.65 6.23 0.32 1.38e-9 IgG glycosylation; LIHC cis rs5769707 0.933 rs2157444 chr22:49994292 A/G cg07959070 chr22:50026188 C22orf34 -0.31 -7.9 -0.39 3.93e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6912958 0.712 rs2754260 chr6:88397666 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.71 -0.38 1.38e-13 Monocyte percentage of white cells; LIHC cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2016586 0.929 rs5999960 chr22:36105267 T/A cg26342177 chr22:36113512 APOL5 -0.38 -6.22 -0.32 1.41e-9 Body mass index; LIHC cis rs6546550 0.935 rs13392884 chr2:70036711 A/G cg02498382 chr2:70120550 SNRNP27 -0.42 -6.87 -0.35 3.1e-11 Prevalent atrial fibrillation; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg25920645 chr2:176047472 ATP5G3 -0.32 -6.53 -0.33 2.45e-10 Calcium levels; LIHC cis rs12477438 0.798 rs6736064 chr2:99658201 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.53 -0.49 1.24e-22 Chronic sinus infection; LIHC cis rs473651 0.935 rs515412 chr2:239345394 A/T cg08773314 chr2:239334832 ASB1 0.3 5.71 0.3 2.44e-8 Multiple system atrophy; LIHC cis rs2732480 0.500 rs7966829 chr12:48615603 G/T cg21466736 chr12:48725269 NA -0.65 -9.8 -0.47 3.87e-20 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs3736485 0.966 rs28376817 chr15:51889280 A/T cg08986416 chr15:51914746 DMXL2 -0.4 -5.73 -0.3 2.2e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs861020 0.710 rs7516902 chr1:210022179 A/G cg05527609 chr1:210001259 C1orf107 1.02 16.61 0.67 7.62e-46 Orofacial clefts; LIHC trans rs2665103 0.687 rs11633000 chr15:82561661 C/G cg18393722 chr15:85113863 UBE2QP1 -0.46 -7.28 -0.37 2.25e-12 Intelligence (multi-trait analysis); LIHC cis rs7572733 0.534 rs1435568 chr2:198762879 T/C cg10820045 chr2:198174542 NA 0.48 7.27 0.37 2.45e-12 Dermatomyositis; LIHC cis rs7617480 0.648 rs6806356 chr3:48727636 G/A cg07636037 chr3:49044803 WDR6 0.7 7.91 0.39 3.57e-14 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs2404602 0.684 rs28895952 chr15:76856776 A/G cg23625390 chr15:77176239 SCAPER -0.54 -8.96 -0.44 2.11e-17 Blood metabolite levels; LIHC cis rs600806 0.850 rs4970846 chr1:109946095 A/C cg16275483 chr1:110013120 SYPL2 -0.46 -5.72 -0.3 2.38e-8 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.966 rs34776628 chr10:35426324 G/A cg03585969 chr10:35415529 CREM 0.85 12.94 0.57 1.93e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2933343 0.700 rs6787833 chr3:128656184 A/G cg24203234 chr3:128598194 ACAD9 0.45 6.33 0.32 7.77e-10 IgG glycosylation; LIHC cis rs35306767 0.761 rs12770173 chr10:1027108 A/C cg26597838 chr10:835615 NA 0.9 8.19 0.41 5.11e-15 Eosinophil percentage of granulocytes; LIHC cis rs6963495 0.818 rs73190183 chr7:105163022 G/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs11039100 0.850 rs12796660 chr11:5843681 T/C cg11650987 chr12:10280440 CLEC7A 0.4 6.11 0.31 2.69e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7615952 0.641 rs6438951 chr3:125696999 A/G cg05084668 chr3:125655381 ALG1L -0.42 -6.72 -0.34 7.77e-11 Blood pressure (smoking interaction); LIHC cis rs12701220 0.901 rs12701708 chr7:1090333 C/T cg26769984 chr7:1090371 C7orf50 0.61 7.98 0.4 2.27e-14 Bronchopulmonary dysplasia; LIHC cis rs12586317 0.547 rs2254990 chr14:35465565 T/C cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.04e-32 Psoriasis; LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 9.37e-15 Prudent dietary pattern; LIHC cis rs1355223 0.583 rs2915238 chr11:34884405 C/A cg24088639 chr11:34937564 PDHX;APIP -0.38 -5.95 -0.31 6.46e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7116495 0.609 rs73531955 chr11:71687794 A/C cg26138937 chr11:71823887 C11orf51 1.31 10.34 0.49 5.49e-22 Severe influenza A (H1N1) infection; LIHC trans rs208520 0.874 rs208469 chr6:66915891 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.7 -7.79 -0.39 8.37e-14 Exhaled nitric oxide output; LIHC cis rs7208859 0.673 rs9909497 chr17:29173228 C/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7107174 1.000 rs11601590 chr11:78073288 T/G cg02023728 chr11:77925099 USP35 0.41 7.9 0.39 3.83e-14 Testicular germ cell tumor; LIHC trans rs561341 0.830 rs2301765 chr17:30202056 T/A cg20587970 chr11:113659929 NA 0.72 8.17 0.4 6.16e-15 Hip circumference adjusted for BMI; LIHC trans rs877282 0.853 rs4579862 chr10:753298 A/C cg22713356 chr15:30763199 NA 1.29 11.19 0.52 5.54e-25 Uric acid levels; LIHC trans rs35110281 0.641 rs4818858 chr21:45083097 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO -0.47 -6.25 -0.32 1.22e-9 Mean corpuscular volume; LIHC cis rs10751667 0.600 rs10902266 chr11:1005697 G/T cg20946044 chr11:1010712 AP2A2 -0.33 -5.78 -0.3 1.68e-8 Alzheimer's disease (late onset); LIHC cis rs9611565 0.649 rs5751144 chr22:42128097 A/G cg06634786 chr22:41940651 POLR3H -0.55 -6.04 -0.31 4.01e-9 Vitiligo; LIHC trans rs7395662 0.591 rs4882085 chr11:48504569 C/G cg15704280 chr7:45808275 SEPT13 -0.46 -6.82 -0.35 4.2e-11 HDL cholesterol; LIHC cis rs7312933 0.703 rs7957471 chr12:42545591 G/T cg01256987 chr12:42539512 GXYLT1 -0.42 -6.99 -0.35 1.45e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg14159672 chr1:205819179 PM20D1 0.86 12.54 0.56 5.89e-30 Menarche (age at onset); LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.65 9.34 0.45 1.27e-18 Lymphocyte counts; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09372778 chr14:24702290 GMPR2;NEDD8 0.41 6.47 0.33 3.39e-10 Cognitive function; LIHC cis rs35306767 0.855 rs12771179 chr10:872347 A/G cg20503657 chr10:835505 NA 1.34 13.9 0.6 3.84e-35 Eosinophil percentage of granulocytes; LIHC cis rs10792665 0.902 rs7930571 chr11:82651948 G/A cg24227371 chr11:82718527 RAB30 -0.3 -7.04 -0.36 1.09e-11 Obesity-related traits; LIHC cis rs11671005 0.735 rs11667723 chr19:58927489 A/G cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs10847980 0.590 rs75794148 chr12:123287329 C/G cg18912006 chr12:123335444 HIP1R 0.73 7.15 0.36 5.33e-12 Adiponectin levels; LIHC cis rs9303401 0.703 rs9909925 chr17:57210069 C/T cg12560992 chr17:57184187 TRIM37 -0.55 -7.69 -0.38 1.5700000000000001e-13 Cognitive test performance; LIHC trans rs3749237 0.964 rs2352967 chr3:49871641 C/T cg21659725 chr3:3221576 CRBN 0.78 12.12 0.55 2.23e-28 Resting heart rate; LIHC cis rs6570726 0.935 rs408723 chr6:145838535 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs36051895 0.664 rs3780373 chr9:5098223 T/C cg02405213 chr9:5042618 JAK2 -0.68 -11.6 -0.53 1.86e-26 Pediatric autoimmune diseases; LIHC cis rs1669338 0.588 rs73005226 chr3:3195369 A/G cg16797762 chr3:3221439 CRBN -0.96 -8.77 -0.43 8.81e-17 White matter integrity; LIHC cis rs7592578 0.766 rs35818159 chr2:191409616 C/G cg10560079 chr2:191398806 TMEM194B -0.87 -12.52 -0.56 7.56e-30 Diastolic blood pressure; LIHC cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg23205692 chr1:25664452 TMEM50A 0.39 6.26 0.32 1.13e-9 Erythrocyte sedimentation rate; LIHC cis rs7618501 0.633 rs55751738 chr3:49972101 A/G cg24110177 chr3:50126178 RBM5 -0.47 -7.67 -0.38 1.86e-13 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.690 rs34818745 chr4:120257055 T/C cg09307838 chr4:120376055 NA 0.74 10.89 0.51 6.82e-24 Corneal astigmatism; LIHC cis rs55882075 0.634 rs11249657 chr5:179111637 G/C cg14593053 chr5:179126677 CANX 0.37 6.29 0.32 9.93e-10 Monocyte percentage of white cells; LIHC cis rs17102423 0.723 rs8181937 chr14:65555707 A/C cg11161011 chr14:65562177 MAX -0.53 -7.6 -0.38 2.92e-13 Obesity-related traits; LIHC cis rs2708977 0.867 rs12717782 chr2:97254116 G/A cg01950434 chr2:97203154 ARID5A 0.49 6.24 0.32 1.27e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs5758511 0.634 rs1001587 chr22:42670111 C/T cg00645731 chr22:42541494 CYP2D7P1 0.52 8.32 0.41 2.16e-15 Birth weight; LIHC cis rs67981189 0.513 rs2526856 chr14:71412717 A/G cg15816911 chr14:71606274 NA 0.43 6.8 0.35 4.6e-11 Schizophrenia; LIHC trans rs1005277 0.579 rs1740747 chr10:38520465 G/A cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC trans rs10213084 1.000 rs13120781 chr4:147480413 T/C cg18061433 chr10:21435895 C10orf113;NEBL 0.52 6.23 0.32 1.37e-9 Heart rate; LIHC cis rs28830936 0.967 rs9672671 chr15:41917075 C/T cg17847044 chr15:42102381 MAPKBP1 -0.3 -6.02 -0.31 4.61e-9 Diastolic blood pressure; LIHC cis rs782590 0.902 rs2586947 chr2:55854009 C/G cg18811423 chr2:55921094 PNPT1 0.95 15.13 0.63 5.74e-40 Metabolic syndrome; LIHC cis rs11077998 0.933 rs4239021 chr17:80531826 T/C cg10255544 chr17:80519551 FOXK2 0.48 8.53 0.42 4.96e-16 Reticulocyte fraction of red cells; LIHC cis rs13108904 0.901 rs7695691 chr4:1304632 A/G cg16405210 chr4:1374714 KIAA1530 -0.55 -8.49 -0.42 6.56e-16 Obesity-related traits; LIHC cis rs992157 0.798 rs7557709 chr2:219167529 G/A cg00012203 chr2:219082015 ARPC2 0.84 13.52 0.59 1.14e-33 Colorectal cancer; LIHC cis rs3749237 0.595 rs885592 chr3:49497883 T/G cg07636037 chr3:49044803 WDR6 0.56 8.5 0.42 5.79e-16 Resting heart rate; LIHC cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg00149659 chr3:10157352 C3orf10 0.68 7.2 0.36 3.97e-12 Alzheimer's disease; LIHC cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg21782813 chr7:2030301 MAD1L1 0.44 7.64 0.38 2.22e-13 Bipolar disorder and schizophrenia; LIHC cis rs9517320 0.534 rs9556963 chr13:99157026 G/A cg20487152 chr13:99095054 FARP1 -0.4 -6.78 -0.34 5.41e-11 Longevity; LIHC cis rs6121246 0.529 rs6060291 chr20:30198043 T/G cg13852791 chr20:30311386 BCL2L1 0.76 6.82 0.35 4.02e-11 Mean corpuscular hemoglobin; LIHC cis rs6754311 0.597 rs2278544 chr2:136546110 A/G cg07169764 chr2:136633963 MCM6 -0.75 -10.79 -0.5 1.54e-23 Mosquito bite size; LIHC cis rs6442522 1.000 rs6778562 chr3:15482775 C/G cg16303742 chr3:15540471 COLQ 0.45 7.46 0.37 7.36e-13 Uric acid levels; LIHC trans rs1945213 0.694 rs7129022 chr11:55876132 A/G cg15704280 chr7:45808275 SEPT13 0.61 7.68 0.38 1.65e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs4888262 0.545 rs7195499 chr16:74693973 C/G cg01733217 chr16:74700730 RFWD3 0.87 17.8 0.69 1.21e-50 Testicular germ cell tumor; LIHC cis rs929354 0.772 rs6459739 chr7:156998863 A/T cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.88e-9 Body mass index; LIHC cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.22 0.32 1.43e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs548181 0.736 rs540723 chr11:125489621 A/G cg03464685 chr11:125439445 EI24 0.86 9.46 0.46 5.31e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7635838 0.573 rs73019547 chr3:11493323 A/C cg00170343 chr3:11313890 ATG7 0.41 6.37 0.33 6.22e-10 HDL cholesterol; LIHC cis rs6121246 0.865 rs6058421 chr20:30295013 G/C cg13852791 chr20:30311386 BCL2L1 0.97 9.8 0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs7116495 0.881 rs475759 chr11:71578992 C/T cg26138937 chr11:71823887 C11orf51 0.67 6.6 0.34 1.58e-10 Severe influenza A (H1N1) infection; LIHC cis rs8056893 0.714 rs1465470 chr16:68397909 A/G cg02226672 chr16:68398533 SMPD3 0.43 6.06 0.31 3.58e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00185336 chr7:73153699 ABHD11 0.42 6.03 0.31 4.14e-9 Pancreatic cancer; LIHC cis rs1371867 0.875 rs2439456 chr8:101336874 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -8.94 -0.44 2.54e-17 Atrioventricular conduction; LIHC cis rs798766 1.000 rs1665366 chr4:1728381 A/G cg21231739 chr4:1642635 FAM53A 0.37 5.86 0.3 1.07e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs919433 0.929 rs10931779 chr2:198166825 A/G cg10820045 chr2:198174542 NA -0.62 -10.56 -0.5 9.39e-23 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7635838 0.750 rs2648463 chr3:11403857 G/A cg00170343 chr3:11313890 ATG7 0.49 7.84 0.39 5.64e-14 HDL cholesterol; LIHC cis rs67311347 0.506 rs55962832 chr3:40244451 T/C cg13409248 chr3:40428643 ENTPD3 0.41 6.41 0.33 4.84e-10 Renal cell carcinoma; LIHC cis rs17685 0.712 rs869805 chr7:75688596 C/T cg04592579 chr7:75616294 TMEM120A 0.4 7.0 0.35 1.32e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs11638815 0.520 rs4779032 chr15:83245326 A/G cg18393722 chr15:85113863 UBE2QP1 -0.37 -6.6 -0.34 1.54e-10 Lipoprotein-associated phospholipase A2 activity change in response to statin therapy; LIHC cis rs611744 0.631 rs681963 chr8:109255032 C/A cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg09033563 chr22:24373618 LOC391322 -0.48 -6.74 -0.34 6.79e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7615952 0.599 rs60847438 chr3:125746005 T/C cg05084668 chr3:125655381 ALG1L -0.41 -6.37 -0.33 6.13e-10 Blood pressure (smoking interaction); LIHC cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -13.44 -0.59 2.32e-33 Alzheimer's disease; LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg22907277 chr7:1156413 C7orf50 0.55 8.62 0.42 2.45e-16 Longevity;Endometriosis; LIHC cis rs3812831 0.630 rs9562129 chr13:114917152 A/G cg06611532 chr13:114900021 NA 0.42 7.71 0.38 1.37e-13 Schizophrenia; LIHC cis rs3741404 0.537 rs1123251 chr11:63917601 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.57 -7.14 -0.36 5.58e-12 Platelet count; LIHC cis rs919433 0.927 rs1429412 chr2:198190894 A/G cg10820045 chr2:198174542 NA -0.56 -9.22 -0.45 3.01e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9902453 0.845 rs2617875 chr17:28090024 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.71 11.51 0.53 3.83e-26 Coffee consumption (cups per day); LIHC cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg04944784 chr2:26401820 FAM59B 0.72 9.21 0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs3540 0.597 rs3743409 chr15:91045539 T/A cg22089800 chr15:90895588 ZNF774 -0.57 -7.94 -0.39 3.02e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg11494091 chr17:61959527 GH2 0.44 8.0 0.4 1.94e-14 Prudent dietary pattern; LIHC cis rs3770081 1.000 rs6759489 chr2:86176032 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.39 5.74 0.3 2.06e-8 Facial emotion recognition (sad faces); LIHC cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.79 0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs854765 0.647 rs854767 chr17:18018263 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.33 -6.5 -0.33 2.8e-10 Total body bone mineral density; LIHC cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg16822855 chr3:40428330 ENTPD3 0.31 5.77 0.3 1.8e-8 Renal cell carcinoma; LIHC cis rs2153535 0.580 rs9406164 chr6:8470048 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs10216189 0.785 rs10807949 chr7:5528375 C/T cg05318486 chr7:5553423 FBXL18 0.42 5.85 0.3 1.16e-8 Relative hand skill in reading disability; LIHC cis rs72627123 0.867 rs118113209 chr14:74432158 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.48 0.42 6.78e-16 Morning vs. evening chronotype; LIHC cis rs546131 0.642 rs12278295 chr11:34846254 G/A cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.47 -0.33 3.33e-10 Lung disease severity in cystic fibrosis; LIHC cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.7 0.57 1.57e-30 Total body bone mineral density; LIHC cis rs11628318 0.853 rs7140280 chr14:103026991 C/T cg01864069 chr14:103024347 NA -0.55 -9.19 -0.44 3.96e-18 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01029676 chr3:122785968 PDIA5 -0.49 -6.73 -0.34 7.05e-11 Pancreatic cancer; LIHC cis rs1881396 0.945 rs1881395 chr2:27838549 G/A cg27432699 chr2:27873401 GPN1 0.47 6.92 0.35 2.21e-11 Nonalcoholic fatty liver disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02447287 chr2:238707023 RBM44 -0.41 -6.45 -0.33 3.82e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.780 rs7680914 chr4:120563053 A/G cg09307838 chr4:120376055 NA 0.73 10.95 0.51 3.91e-24 Corneal astigmatism; LIHC cis rs6840360 0.615 rs1561917 chr4:152479233 G/A cg22705602 chr4:152727874 NA -0.33 -6.35 -0.32 6.71e-10 Intelligence (multi-trait analysis); LIHC cis rs1816752 0.905 rs9511242 chr13:24993399 G/A cg22771759 chr13:24902376 NA 0.33 6.65 0.34 1.14e-10 Obesity-related traits; LIHC cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg03264133 chr6:25882463 NA -1.18 -19.07 -0.72 9.98e-56 Urate levels; LIHC cis rs928736 0.557 rs2834083 chr21:34436973 A/G cg00274965 chr21:34405681 NA 0.35 6.27 0.32 1.11e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs17001868 0.568 rs9611315 chr22:40736900 A/T cg07138101 chr22:40742427 ADSL 0.54 6.4 0.33 5.03e-10 Mammographic density (dense area); LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs911555 0.511 rs8007489 chr14:104054572 A/G cg24130564 chr14:104152367 KLC1 0.63 11.71 0.53 7.6e-27 Intelligence (multi-trait analysis); LIHC cis rs12915189 1.000 rs7180053 chr15:91114735 T/G cg26821196 chr15:91095069 CRTC3 0.33 5.93 0.31 7.43e-9 Information processing speed; LIHC trans rs877282 0.891 rs11253406 chr10:796297 G/A cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.15e-51 Menopause (age at onset); LIHC cis rs1030877 0.824 rs2576738 chr2:105891644 C/A cg02079111 chr2:105885981 TGFBRAP1 0.66 11.55 0.53 2.78e-26 Obesity-related traits; LIHC cis rs743757 1.000 rs762897 chr3:50428766 C/A cg12708802 chr3:50388878 TUSC4;CYB561D2 0.46 6.95 0.35 1.85e-11 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27433451 chr1:51443332 NA -0.51 -7.27 -0.37 2.51e-12 Pancreatic cancer; LIHC cis rs10744422 0.925 rs897391 chr12:123326374 G/A cg22842854 chr12:123319900 HIP1R -0.65 -8.57 -0.42 3.5e-16 Schizophrenia; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg19687152 chr14:102968497 TECPR2 0.45 6.68 0.34 9.8e-11 Electroencephalogram traits; LIHC cis rs9426691 1 rs9426691 chr1:23484904 A/G cg12483005 chr1:23474871 LUZP1 0.44 6.82 0.35 4.08e-11 Coenzyme Q10 levels; LIHC cis rs9915021 0.623 rs12452797 chr17:33890976 C/G cg20932281 chr17:33905541 PEX12 0.62 7.69 0.38 1.55e-13 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs12431939 1.000 rs11850391 chr14:51639759 A/G cg23942311 chr14:51606299 NA -0.35 -5.92 -0.31 7.66e-9 Cancer; LIHC cis rs11123170 0.650 rs2289897 chr2:113977454 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.53 6.49 0.33 2.99e-10 Renal function-related traits (BUN); LIHC cis rs3749237 0.595 rs11130199 chr3:49538799 T/C cg07636037 chr3:49044803 WDR6 0.53 8.08 0.4 1.1e-14 Resting heart rate; LIHC cis rs34172651 0.517 rs200526 chr16:24760511 C/T cg00339695 chr16:24857497 SLC5A11 -0.71 -10.73 -0.5 2.4e-23 Intelligence (multi-trait analysis); LIHC cis rs3796352 0.881 rs34238610 chr3:53026480 A/T cg07884673 chr3:53033167 SFMBT1 0.93 6.67 0.34 1.05e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7584330 0.554 rs79020383 chr2:238425834 G/A cg08992911 chr2:238395768 MLPH 0.51 6.23 0.32 1.39e-9 Prostate cancer; LIHC cis rs11971779 0.553 rs11973507 chr7:139099461 A/T cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC trans rs1814175 0.615 rs7113020 chr11:49746540 C/T cg03929089 chr4:120376271 NA -0.86 -17.01 -0.68 1.92e-47 Height; LIHC cis rs8180040 0.800 rs62248905 chr3:47274082 A/G cg27129171 chr3:47204927 SETD2 -0.56 -9.11 -0.44 6.87e-18 Colorectal cancer; LIHC cis rs7131987 0.934 rs7316004 chr12:29411698 C/T cg21522988 chr12:29376872 FAR2 0.3 6.86 0.35 3.28e-11 QT interval; LIHC cis rs8078723 0.763 rs4433838 chr17:38143532 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.29 0.52 2.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs853679 0.517 rs6922063 chr6:28094366 G/A cg16479474 chr6:28041457 NA 0.46 6.58 0.34 1.79e-10 Depression; LIHC cis rs7146395 1 rs7146395 chr14:75228647 A/C cg11812906 chr14:75593930 NEK9 0.41 6.32 0.32 8.3e-10 Platelet count; LIHC cis rs17094222 0.812 rs11190658 chr10:102443374 C/T cg26540559 chr10:102447443 NA 0.32 5.9 0.3 8.91e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12101261 1.000 rs4903961 chr14:81462649 C/G cg06600135 chr14:81408086 NA 0.37 6.33 0.32 7.5e-10 Graves' disease; LIHC cis rs12497850 0.865 rs13072911 chr3:48962128 T/G cg06212747 chr3:49208901 KLHDC8B 0.57 7.31 0.37 1.87e-12 Parkinson's disease; LIHC cis rs7512552 0.839 rs12042229 chr1:150447398 A/G cg15654264 chr1:150340011 RPRD2 0.68 11.2 0.52 5.36e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs8050260 0.500 rs4783650 chr16:68558528 T/C cg02972257 chr16:68554789 NA 0.59 6.37 0.33 6.14e-10 Plateletcrit; LIHC cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg22442454 chr1:209979470 IRF6 0.4 6.08 0.31 3.28e-9 Cleft lip with or without cleft palate; LIHC cis rs1568889 0.838 rs10835273 chr11:28156598 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.18 0.61 3.24e-36 Bipolar disorder; LIHC trans rs7618501 0.665 rs7621352 chr3:50070763 A/C cg21659725 chr3:3221576 CRBN -0.71 -11.63 -0.53 1.48e-26 Intelligence (multi-trait analysis); LIHC cis rs875971 0.545 rs11770063 chr7:65783016 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.24 0.36 3.03e-12 Aortic root size; LIHC trans rs56292044 0.706 rs10104949 chr8:138775701 A/G cg05886954 chr16:3631570 BTBD12 -0.31 -6.1 -0.31 2.82e-9 Post bronchodilator FEV1/FVC ratio in COPD; LIHC cis rs919433 0.680 rs2244271 chr2:198286581 C/T cg03934865 chr2:198174659 NA 0.54 8.15 0.4 6.71e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11122272 0.735 rs2486727 chr1:231539245 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -10.36 -0.49 4.61e-22 Hemoglobin concentration; LIHC cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.07 -0.55 3.6e-28 Alzheimer's disease; LIHC cis rs9640161 0.750 rs1983440 chr7:150023941 G/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.79 -0.43 7.56e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs963731 0.649 rs12620071 chr2:39345873 G/A cg04010122 chr2:39346883 SOS1 0.68 5.88 0.3 9.58e-9 Corticobasal degeneration; LIHC cis rs9486715 0.809 rs9486467 chr6:96971803 C/T cg18709589 chr6:96969512 KIAA0776 0.34 6.03 0.31 4.27e-9 Headache; LIHC cis rs12579753 1.000 rs34894912 chr12:82228721 A/G cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg03517284 chr6:25882590 NA -0.63 -8.86 -0.43 4.45e-17 Blood metabolite levels; LIHC cis rs4555082 0.957 rs2816629 chr14:105737261 G/A cg13114125 chr14:105738426 BRF1 -0.7 -9.6 -0.46 1.75e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs3806843 1.000 rs3733708 chr5:140181734 A/G cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.21e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7249142 0.549 rs539 chr19:19287802 A/G cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.34 -5.83 -0.3 1.29e-8 IgG glycosylation; LIHC cis rs208520 0.526 rs9363522 chr6:66816642 C/T cg07460842 chr6:66804631 NA -1.01 -19.65 -0.73 4.33e-58 Exhaled nitric oxide output; LIHC cis rs4965272 0.830 rs11631633 chr15:100560186 C/A cg09918751 chr15:100517450 ADAMTS17 -0.43 -5.91 -0.3 8.33e-9 Gastroesophageal reflux disease; LIHC cis rs11190604 0.767 rs10748794 chr10:102175918 G/T cg07080220 chr10:102295463 HIF1AN -0.41 -5.8 -0.3 1.48e-8 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7726839 0.540 rs7434 chr5:660804 A/G cg09021430 chr5:549028 NA 0.42 8.54 0.42 4.51e-16 Obesity-related traits; LIHC cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.08 0.44 9.16e-18 Platelet count; LIHC cis rs9733 0.596 rs11803569 chr1:150664077 C/T cg13175981 chr1:150552382 MCL1 -0.44 -6.06 -0.31 3.55e-9 Tonsillectomy; LIHC cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg01765077 chr12:122356316 WDR66 0.42 6.29 0.32 9.64e-10 Mean corpuscular volume; LIHC cis rs9658691 0.607 rs9658766 chr10:90771612 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.87 -6.63 -0.34 1.34e-10 Mosquito bite size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15688767 chr3:125093330 ZNF148 0.46 7.35 0.37 1.43e-12 Cognitive function; LIHC cis rs9326248 0.520 rs2735183 chr11:117015195 C/T cg11861562 chr11:117069780 TAGLN 0.37 5.98 0.31 5.56e-9 Blood protein levels; LIHC cis rs2239547 0.603 rs2276825 chr3:52886605 T/C cg11645453 chr3:52864694 ITIH4 0.36 9.34 0.45 1.29e-18 Schizophrenia; LIHC cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.61e-12 Intelligence (multi-trait analysis); LIHC cis rs12699477 0.545 rs117125814 chr7:1910681 T/G cg02951883 chr7:2050386 MAD1L1 -0.55 -8.24 -0.41 3.72e-15 Testicular germ cell tumor; LIHC cis rs9611565 0.877 rs3817999 chr22:41747717 A/G cg03806693 chr22:41940476 POLR3H 0.49 6.51 0.33 2.72e-10 Vitiligo; LIHC cis rs921968 0.643 rs2556386 chr2:219534530 C/T cg02985541 chr2:219472218 PLCD4 -0.42 -7.65 -0.38 2.07e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.9 0.35 2.6e-11 Gut microbiome composition (summer); LIHC cis rs11229555 0.645 rs12802960 chr11:58174775 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs11098499 0.863 rs2306456 chr4:120472422 C/G cg25214090 chr10:38739885 LOC399744 0.59 9.48 0.46 4.25e-19 Corneal astigmatism; LIHC cis rs4713118 0.869 rs10214440 chr6:27702440 A/C cg20933634 chr6:27740509 NA 0.47 6.16 0.32 2.09e-9 Parkinson's disease; LIHC cis rs2191566 1.000 rs2356549 chr19:44511202 A/T cg20607764 chr19:44506953 ZNF230 -0.45 -7.38 -0.37 1.22e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs1577917 1.000 rs1999852 chr6:86705738 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.73 -0.34 7.14e-11 Response to antipsychotic treatment; LIHC cis rs1707322 0.752 rs11211145 chr1:46108491 A/C cg24296786 chr1:45957014 TESK2 -0.41 -5.75 -0.3 2.03e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9916302 0.904 rs587343 chr17:37440603 C/T cg00129232 chr17:37814104 STARD3 0.39 6.24 0.32 1.29e-9 Glomerular filtration rate (creatinine); LIHC cis rs875971 0.660 rs801192 chr7:66031952 C/G cg11764359 chr7:65958608 NA -0.72 -10.98 -0.51 3.13e-24 Aortic root size; LIHC cis rs11098499 0.863 rs2306456 chr4:120472422 C/G cg09307838 chr4:120376055 NA 0.76 11.48 0.53 5.12e-26 Corneal astigmatism; LIHC cis rs7903847 0.596 rs7922512 chr10:99155685 C/A cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs875971 0.790 rs10257911 chr7:65743770 A/G cg18876405 chr7:65276391 NA -0.34 -6.29 -0.32 9.71e-10 Aortic root size; LIHC cis rs8103278 1.000 rs8102876 chr19:46332842 C/T cg11657440 chr19:46296263 DMWD -0.54 -8.28 -0.41 2.75e-15 Coronary artery disease; LIHC cis rs11602339 1 rs11602339 chr11:47761471 C/T cg20135002 chr11:47629003 NA -0.54 -9.26 -0.45 2.36e-18 Body mass index; LIHC cis rs1005277 0.579 rs2800485 chr10:38542588 G/A cg00409905 chr10:38381863 ZNF37A -0.55 -9.08 -0.44 8.66e-18 Extrinsic epigenetic age acceleration; LIHC cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg16414030 chr3:133502952 NA 0.4 6.21 0.32 1.58e-9 Iron status biomarkers; LIHC cis rs11122272 0.735 rs2790881 chr1:231534181 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.73e-19 Hemoglobin concentration; LIHC trans rs6951245 0.638 rs4720486 chr7:1146764 G/A cg13565492 chr6:43139072 SRF -0.79 -7.4 -0.37 1.03e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6951245 0.554 rs78999139 chr7:1138525 G/A cg04025307 chr7:1156635 C7orf50 0.64 6.34 0.32 7.25e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg20295408 chr7:1910781 MAD1L1 0.44 6.51 0.33 2.75e-10 Bipolar disorder and schizophrenia; LIHC cis rs7772486 0.686 rs2092263 chr6:146029687 G/A cg23711669 chr6:146136114 FBXO30 -0.63 -11.62 -0.53 1.55e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg21951975 chr1:209979733 IRF6 0.4 6.47 0.33 3.38e-10 Cleft lip with or without cleft palate; LIHC cis rs651907 0.737 rs9844218 chr3:101584983 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.54 -7.5 -0.38 5.51e-13 Colorectal cancer; LIHC cis rs11628318 0.570 rs4906231 chr14:103062227 T/C cg23461800 chr14:103021989 NA -0.43 -6.12 -0.31 2.62e-9 Platelet count; LIHC cis rs9916302 0.629 rs9972882 chr17:37807698 A/C cg07936489 chr17:37558343 FBXL20 -0.48 -7.06 -0.36 9.13e-12 Glomerular filtration rate (creatinine); LIHC cis rs12086130 0.892 rs6694036 chr1:51452068 T/A cg07174182 chr1:51127561 FAF1 -0.92 -9.87 -0.47 2.14e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs9733 0.818 rs11204702 chr1:150663507 C/A cg18016565 chr1:150552671 MCL1 -0.5 -10.31 -0.49 6.78e-22 Tonsillectomy; LIHC cis rs7793919 0.764 rs6944865 chr7:4766383 A/T cg09789173 chr7:4769017 FOXK1 0.7 10.37 0.49 4.49e-22 Mosquito bite size; LIHC cis rs67478160 0.634 rs2368558 chr14:104230518 A/G cg01849466 chr14:104193079 ZFYVE21 -0.52 -9.11 -0.44 7.27e-18 Schizophrenia; LIHC cis rs3741404 0.609 rs669913 chr11:63869879 A/G cg05016508 chr11:63871570 FLRT1;MACROD1 0.42 6.62 0.34 1.43e-10 Platelet count; LIHC trans rs6934970 1.000 rs4945480 chr6:113120853 A/G cg05569086 chr8:143859399 LYNX1 -0.55 -6.04 -0.31 3.93e-9 Bipolar disorder (body mass index interaction); LIHC cis rs11676348 0.846 rs3890158 chr2:218990292 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.45 -6.22 -0.32 1.45e-9 Ulcerative colitis; LIHC cis rs17345786 0.798 rs4257518 chr3:101281709 C/T cg11279151 chr3:101281821 RG9MTD1 0.53 8.67 0.42 1.75e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs12540874 0.529 rs732215 chr7:50544063 A/C cg18232548 chr7:50535776 DDC -0.4 -5.92 -0.3 7.97e-9 Systemic sclerosis; LIHC cis rs11673344 0.864 rs703530 chr19:37500918 G/A cg27390819 chr19:37464633 NA -0.52 -6.38 -0.33 5.73e-10 Obesity-related traits; LIHC cis rs8180040 0.676 rs7633698 chr3:47013452 A/T cg27129171 chr3:47204927 SETD2 0.62 10.8 0.5 1.4e-23 Colorectal cancer; LIHC cis rs6835098 0.961 rs28709762 chr4:174099149 T/C cg27433088 chr4:174089019 GALNT7 0.41 7.01 0.35 1.25e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs7188697 0.922 rs1981961 chr16:58597291 A/T cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs4746818 1.000 rs4342912 chr10:70959282 T/C cg11621586 chr10:70884670 VPS26A 0.84 13.57 0.59 7.09e-34 Left atrial antero-posterior diameter; LIHC cis rs12701220 0.604 rs34904312 chr7:1135883 G/A cg04025307 chr7:1156635 C7orf50 0.55 7.3 0.37 1.97e-12 Bronchopulmonary dysplasia; LIHC cis rs4555082 0.957 rs10140586 chr14:105749582 A/G cg06808227 chr14:105710500 BRF1 -0.61 -8.48 -0.42 7.08e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs9399135 0.935 rs2150680 chr6:135347131 G/C cg22676075 chr6:135203613 NA 0.39 6.32 0.32 8.12e-10 Red blood cell count; LIHC cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg11890956 chr21:40555474 PSMG1 1.07 15.39 0.64 5.41e-41 Cognitive function; LIHC cis rs3857067 0.806 rs12513267 chr4:95109545 C/T cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.46 -0.37 7.07e-13 QT interval; LIHC cis rs12928939 0.815 rs8049163 chr16:71719353 C/T cg03805757 chr16:71968109 PKD1L3 -0.68 -7.8 -0.39 7.8e-14 Post bronchodilator FEV1; LIHC cis rs912057 0.601 rs1294405 chr6:6737591 A/G cg06612196 chr6:6737390 NA 0.59 10.92 0.51 5.04e-24 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC trans rs2211698 1.000 rs4384872 chr21:35837113 A/G cg18044562 chr7:50468399 IKZF1 0.51 7.42 0.37 9.41e-13 Cancer; LIHC cis rs2279817 0.818 rs34036216 chr1:17986046 C/T cg21791023 chr1:18019539 ARHGEF10L -0.65 -7.22 -0.36 3.45e-12 Neuroticism; LIHC cis rs11628318 0.853 rs10151896 chr14:103039936 G/C cg01864069 chr14:103024347 NA -0.57 -9.52 -0.46 3.36e-19 Platelet count; LIHC cis rs17125944 0.615 rs2025633 chr14:53317340 C/T cg00686598 chr14:53173677 PSMC6 -0.84 -9.96 -0.47 1.07e-20 Alzheimer's disease (late onset); LIHC cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg18225595 chr11:63971243 STIP1 0.63 8.03 0.4 1.54e-14 Mean platelet volume; LIHC cis rs3741798 1.000 rs2160588 chr12:12487447 C/T cg08615371 chr12:12503544 MANSC1 0.97 8.5 0.42 6.05e-16 Cerebrospinal fluid biomarker levels; LIHC cis rs4759375 0.510 rs12367421 chr12:123783691 T/A cg00376283 chr12:123451042 ABCB9 -0.49 -6.31 -0.32 8.53e-10 HDL cholesterol; LIHC cis rs1691799 0.867 rs1027399 chr12:66760942 G/A cg16791601 chr12:66731901 HELB -0.54 -13.08 -0.58 5.78e-32 White blood cell count (basophil); LIHC cis rs4820539 0.966 rs5759594 chr22:23470660 G/A cg14186256 chr22:23484241 RTDR1 0.99 21.35 0.76 6.81e-65 Bone mineral density; LIHC cis rs5753618 0.539 rs5997933 chr22:31672752 A/C cg07713946 chr22:31675144 LIMK2 -0.43 -7.78 -0.39 8.78e-14 Colorectal cancer; LIHC cis rs7613875 0.600 rs2624848 chr3:50165101 T/C cg24110177 chr3:50126178 RBM5 0.6 9.74 0.47 5.95e-20 Body mass index; LIHC cis rs2997447 0.723 rs2802338 chr1:26475257 G/A cg19633962 chr1:26362018 EXTL1 -0.55 -6.43 -0.33 4.22e-10 QRS complex (12-leadsum); LIHC trans rs1005277 0.529 rs1780125 chr10:38531376 A/G cg23533926 chr12:111358616 MYL2 -0.36 -6.86 -0.35 3.18e-11 Extrinsic epigenetic age acceleration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02763798 chr12:58335209 XRCC6BP1 0.47 6.33 0.32 7.61e-10 Lung function (FEV1/FVC); LIHC cis rs1707322 1.000 rs10890375 chr1:46406581 G/A cg03146154 chr1:46216737 IPP 0.48 7.85 0.39 5.51e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10420951 0.617 rs7246328 chr19:18619057 T/C cg10790698 chr19:18539756 SSBP4 -0.42 -5.93 -0.31 7.27e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg18404041 chr3:52824283 ITIH1 -0.47 -7.7 -0.38 1.51e-13 Electroencephalogram traits; LIHC cis rs2832191 0.632 rs1984011 chr21:30337831 T/A cg24692254 chr21:30365293 RNF160 -0.84 -14.47 -0.62 2.29e-37 Dental caries; LIHC cis rs11122272 0.667 rs2244992 chr1:231537220 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.75e-22 Hemoglobin concentration; LIHC cis rs2997447 0.655 rs1317709 chr1:26384690 A/C cg19633962 chr1:26362018 EXTL1 -0.55 -6.97 -0.35 1.59e-11 QRS complex (12-leadsum); LIHC cis rs3741404 0.560 rs12362602 chr11:63908660 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.7 -10.52 -0.49 1.32e-22 Platelet count; LIHC cis rs3853824 0.965 rs6503764 chr17:54880082 T/C cg13675837 chr17:54910204 DGKE 0.39 5.88 0.3 9.79e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6500602 0.702 rs4786511 chr16:4571645 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.44 6.11 0.31 2.71e-9 Schizophrenia; LIHC cis rs7100689 0.646 rs1340375 chr10:82129039 C/T cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07421368 chr2:67624930 ETAA1 0.5 7.58 0.38 3.33e-13 Cognitive function; LIHC cis rs9916302 0.904 rs2024073 chr17:37471330 T/G cg03013999 chr17:37608204 MED1 -0.36 -6.01 -0.31 4.76e-9 Glomerular filtration rate (creatinine); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07161888 chr16:53537348 AKTIP 0.43 6.16 0.32 2.07e-9 Lung function (FEV1/FVC); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12390003 chr1:160068671 IGSF8 0.48 6.68 0.34 9.89e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7512552 0.839 rs6703652 chr1:150465953 T/G cg15654264 chr1:150340011 RPRD2 0.69 11.16 0.52 7.11e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs116095464 0.558 rs59113266 chr5:279965 T/C cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs28647808 0.881 rs4962139 chr9:136267869 C/T cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A 0.77 6.2 0.32 1.65e-9 Blood protein levels; LIHC cis rs7208859 0.573 rs8070182 chr17:29135594 A/C cg14067834 chr17:29058358 SUZ12P 0.68 6.72 0.34 7.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs882732 1.000 rs10142033 chr14:95041623 A/T cg14866387 chr14:95027382 SERPINA4 -0.48 -6.45 -0.33 3.82e-10 Blood protein levels; LIHC cis rs62005083 0.500 rs10135300 chr14:74574561 G/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.52 7.16 0.36 4.96e-12 Mean corpuscular volume; LIHC cis rs1843834 0.858 rs4674933 chr2:225514923 C/T cg22455342 chr2:225449267 CUL3 0.46 5.92 0.31 7.67e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs288342 0.832 rs288305 chr2:183652328 C/T cg02625481 chr2:183667124 NA -0.29 -5.96 -0.31 6.2e-9 Recurrent major depressive disorder; LIHC cis rs2842992 0.872 rs9456440 chr6:160074463 G/T cg16489826 chr6:160211363 TCP1;MRPL18 0.5 8.43 0.41 9.98e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg21724239 chr8:58056113 NA 0.57 6.94 0.35 1.94e-11 Developmental language disorder (linguistic errors); LIHC cis rs4690686 0.500 rs7683662 chr4:177272004 A/T cg17059388 chr4:177262070 NA 0.41 7.52 0.38 4.9e-13 Essential tremor; LIHC cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg13393036 chr8:95962371 TP53INP1 -0.37 -8.55 -0.42 4.1e-16 Type 2 diabetes; LIHC cis rs4906332 0.899 rs12888042 chr14:103891709 G/A cg19000871 chr14:103996768 TRMT61A -0.46 -7.85 -0.39 5.38e-14 Coronary artery disease; LIHC cis rs9611565 0.512 rs2899347 chr22:42158204 T/C cg06634786 chr22:41940651 POLR3H 0.75 7.57 0.38 3.48e-13 Vitiligo; LIHC cis rs7772486 0.875 rs10457795 chr6:146415665 A/G cg05347473 chr6:146136440 FBXO30 0.38 5.93 0.31 7.44e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs858239 0.539 rs6955969 chr7:23186699 C/T cg23682824 chr7:23144976 KLHL7 0.42 6.42 0.33 4.64e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg01411255 chr17:61851458 DDX42;CCDC47 -1.0 -22.44 -0.77 3.43e-69 Height; LIHC trans rs7618501 1.000 rs6775384 chr3:49853073 G/A cg21659725 chr3:3221576 CRBN 0.95 17.64 0.69 5.55e-50 Intelligence (multi-trait analysis); LIHC cis rs17125944 0.686 rs7147258 chr14:53337664 G/T cg00686598 chr14:53173677 PSMC6 -0.81 -9.64 -0.46 1.34e-19 Alzheimer's disease (late onset); LIHC cis rs7312933 0.533 rs11181499 chr12:42818761 A/G cg01256987 chr12:42539512 GXYLT1 -0.35 -5.74 -0.3 2.07e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.12 11.35 0.52 1.52e-25 Platelet count; LIHC cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg21448741 chr8:58168803 NA 0.33 6.01 0.31 4.72e-9 Developmental language disorder (linguistic errors); LIHC cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg05535760 chr7:792225 HEATR2 -0.49 -6.83 -0.35 3.9e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs4803468 1.000 rs2241708 chr19:41912270 C/T cg14132834 chr19:41945861 ATP5SL -0.41 -6.05 -0.31 3.82e-9 Height; LIHC cis rs1336900 0.513 rs56253522 chr1:150614869 C/A cg17724175 chr1:150552817 MCL1 0.48 9.37 0.45 1.01e-18 Blood protein levels; LIHC cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg22800045 chr5:56110881 MAP3K1 0.67 8.58 0.42 3.46e-16 Initial pursuit acceleration; LIHC cis rs1552244 0.554 rs55847233 chr3:9991101 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.81 0.39 7.09e-14 Alzheimer's disease; LIHC cis rs12908161 1.000 rs62019469 chr15:85321220 T/C cg17507749 chr15:85114479 UBE2QP1 0.62 7.05 0.36 1.02e-11 Schizophrenia; LIHC cis rs7959452 0.590 rs56054057 chr12:69775972 C/T cg14784868 chr12:69753453 YEATS4 0.94 20.29 0.74 1.24e-60 Blood protein levels; LIHC cis rs4474465 0.850 rs10793328 chr11:78256868 A/G cg27205649 chr11:78285834 NARS2 0.4 5.95 0.31 6.76e-9 Alzheimer's disease (survival time); LIHC cis rs6964587 1.000 rs6465343 chr7:91618208 T/C cg17063962 chr7:91808500 NA 1.03 20.62 0.74 5.72e-62 Breast cancer; LIHC trans rs7504990 0.754 rs1030592 chr18:50374721 T/C cg08535148 chr4:26321143 RBPJ 0.58 7.31 0.37 1.92e-12 Gallbladder cancer; LIHC cis rs7107174 1.000 rs1485483 chr11:77930138 T/C cg02023728 chr11:77925099 USP35 0.51 9.49 0.46 4.22e-19 Testicular germ cell tumor; LIHC cis rs7927771 0.864 rs7107726 chr11:47429245 T/A cg20135002 chr11:47629003 NA -0.58 -10.01 -0.48 7.32e-21 Subjective well-being; LIHC cis rs11626933 0.885 rs28517514 chr14:90788709 G/A cg04374321 chr14:90722782 PSMC1 0.44 6.46 0.33 3.62e-10 Gut microbiota (bacterial taxa); LIHC cis rs12744310 0.887 rs6660265 chr1:41818676 C/T cg03962019 chr1:41807865 NA -0.39 -6.25 -0.32 1.23e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg02782426 chr3:40428986 ENTPD3 -0.32 -6.12 -0.31 2.61e-9 Renal cell carcinoma; LIHC trans rs1005277 0.579 rs2474584 chr10:38416389 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.25 -0.52 3.46e-25 Extrinsic epigenetic age acceleration; LIHC cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg05025164 chr4:1340916 KIAA1530 0.78 12.68 0.57 1.87e-30 Longevity; LIHC cis rs600806 0.714 rs2781552 chr1:110025881 A/G cg02415029 chr1:110025642 ATXN7L2 0.46 6.05 0.31 3.75e-9 Intelligence (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26567012 chr5:151202148 GLRA1 -0.42 -6.51 -0.33 2.66e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1355223 0.902 rs1453387 chr11:34707898 C/G cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.3 -0.32 9.3e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs8060686 0.545 rs78229587 chr16:68165243 T/C cg05110241 chr16:68378359 PRMT7 -0.63 -7.06 -0.36 9.6e-12 HDL cholesterol;Metabolic syndrome; LIHC cis rs7078219 0.505 rs10883372 chr10:101292483 T/A cg06854084 chr10:101292507 NKX2-3 -0.34 -6.22 -0.32 1.44e-9 Dental caries; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13370280 chr6:137539688 IFNGR1 0.52 7.62 0.38 2.44e-13 Pancreatic cancer; LIHC cis rs4780401 0.933 rs4780395 chr16:11809940 A/G cg01061890 chr16:11836724 TXNDC11 -0.4 -5.75 -0.3 2.03e-8 Rheumatoid arthritis; LIHC cis rs57920188 0.535 rs7412438 chr1:4095581 C/G cg20703997 chr1:4087676 NA 0.49 6.1 0.31 2.87e-9 Interleukin-17 levels; LIHC cis rs7945718 0.905 rs6486032 chr11:12723693 G/A cg25843174 chr11:12811716 TEAD1 0.33 7.34 0.37 1.62e-12 Educational attainment (years of education); LIHC cis rs10751667 0.666 rs10794354 chr11:954615 A/T cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.09e-12 Alzheimer's disease (late onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01587390 chr19:10221818 PPAN-P2RY11;P2RY11;PPAN -0.39 -6.04 -0.31 4.08e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6546550 0.901 rs10167142 chr2:70062360 T/C cg02498382 chr2:70120550 SNRNP27 -0.39 -6.54 -0.33 2.24e-10 Prevalent atrial fibrillation; LIHC cis rs9911578 1.000 rs999431 chr17:56854441 A/G cg12560992 chr17:57184187 TRIM37 0.97 17.43 0.69 3.72e-49 Intelligence (multi-trait analysis); LIHC cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.03 -0.31 4.33e-9 Colorectal cancer; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg11494091 chr17:61959527 GH2 0.43 7.73 0.39 1.24e-13 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs2437149 chr1:231490105 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.95 -0.51 4.13e-24 Hemoglobin concentration; LIHC cis rs7020830 0.894 rs28766572 chr9:37093872 G/T cg14294708 chr9:37120828 ZCCHC7 1.01 21.22 0.75 2.26e-64 Schizophrenia; LIHC cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg18225595 chr11:63971243 STIP1 0.66 8.27 0.41 3.06e-15 Mean platelet volume; LIHC cis rs17253792 0.822 rs13379340 chr14:56050346 C/G cg01858014 chr14:56050164 KTN1 -0.75 -8.07 -0.4 1.22e-14 Putamen volume; LIHC cis rs629922 0.642 rs615119 chr11:114072224 T/C cg01914181 chr11:114070210 ZBTB16 0.54 7.52 0.38 4.72e-13 Paneth cell defects in Crohn's disease; LIHC cis rs3816183 1.000 rs920390 chr2:43019144 A/G cg17246140 chr2:43020264 HAAO 0.39 5.82 0.3 1.33e-8 Hypospadias; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19502700 chr4:113558183 LARP7;C4orf21 0.48 7.36 0.37 1.41e-12 Calcium levels; LIHC cis rs7927771 0.965 rs56400411 chr11:47586376 T/G cg20135002 chr11:47629003 NA -0.58 -10.09 -0.48 3.95e-21 Subjective well-being; LIHC cis rs10056811 0.510 rs10058171 chr5:74407991 C/T cg19683494 chr5:74908142 NA 0.7 7.74 0.39 1.14e-13 Coronary artery disease; LIHC cis rs7592578 0.766 rs62181052 chr2:191387858 A/G cg10560079 chr2:191398806 TMEM194B -0.85 -12.16 -0.55 1.6e-28 Diastolic blood pressure; LIHC cis rs12286929 0.606 rs11823428 chr11:115071222 C/A cg04055981 chr11:115044050 NA 0.51 7.94 0.39 2.84e-14 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs11098499 0.743 rs11098501 chr4:120252017 T/G cg25214090 chr10:38739885 LOC399744 0.51 8.25 0.41 3.48e-15 Corneal astigmatism; LIHC cis rs7165170 0.678 rs12592070 chr15:91197016 C/A cg26821196 chr15:91095069 CRTC3 -0.37 -6.9 -0.35 2.54e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs422249 0.615 rs174612 chr11:61628266 C/G cg27386326 chr11:61587980 NA 0.38 6.97 0.35 1.62e-11 Trans fatty acid levels; LIHC cis rs1008375 0.932 rs4698629 chr4:17608884 C/G cg16339924 chr4:17578868 LAP3 0.47 6.24 0.32 1.32e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs67478160 0.654 rs1535097 chr14:104216649 C/T cg08213375 chr14:104286397 PPP1R13B 0.64 12.74 0.57 1.0500000000000001e-30 Schizophrenia; LIHC cis rs8016982 0.674 rs11850714 chr14:81662993 C/G cg01989461 chr14:81687754 GTF2A1 0.7 14.5 0.62 1.81e-37 Schizophrenia; LIHC cis rs1005277 0.579 rs2472175 chr10:38382901 T/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC trans rs6952808 0.572 rs1860826 chr7:2112506 G/A cg04565464 chr8:145669602 NFKBIL2 0.39 6.18 0.32 1.87e-9 Bipolar disorder and schizophrenia; LIHC cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg05025164 chr4:1340916 KIAA1530 0.74 11.05 0.51 1.76e-24 Longevity; LIHC cis rs7581030 0.874 rs4852772 chr2:71443645 A/G cg07678644 chr2:71558969 ZNF638 0.46 6.49 0.33 2.99e-10 Testicular germ cell tumor; LIHC cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg21724239 chr8:58056113 NA 0.48 6.4 0.33 5.2400000000000005e-10 Developmental language disorder (linguistic errors); LIHC cis rs9399135 0.935 rs11754504 chr6:135321509 C/T cg22676075 chr6:135203613 NA 0.39 6.38 0.33 5.82e-10 Red blood cell count; LIHC cis rs7618501 0.966 rs2246832 chr3:49881134 A/T cg21467203 chr3:49911342 NA -0.43 -7.28 -0.37 2.3e-12 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.737 rs10846920 chr12:122943231 C/T cg23029597 chr12:123009494 RSRC2 -0.49 -7.08 -0.36 8.23e-12 Body mass index; LIHC trans rs1499614 1.000 rs2707838 chr7:66159201 C/T cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11227645 chr1:224544764 CNIH4 0.43 6.36 0.33 6.57e-10 Lung function (FEV1/FVC); LIHC trans rs801193 1.000 rs4279493 chr7:66226620 C/T cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.81e-11 Aortic root size; LIHC cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.53e-9 Menopause (age at onset); LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg11494091 chr17:61959527 GH2 0.36 6.09 0.31 2.96e-9 Height; LIHC cis rs12980942 0.872 rs7256416 chr19:41787931 C/T cg25627403 chr19:41769009 HNRNPUL1 0.5 6.29 0.32 9.54e-10 Coronary artery disease; LIHC trans rs1961637 0.603 rs1550423 chr2:223885812 C/T cg05000987 chr1:87379871 SEP15;HS2ST1 -0.39 -6.17 -0.32 1.96e-9 Oropharynx cancer; LIHC cis rs57502260 0.704 rs2306862 chr11:68177510 C/T cg01657329 chr11:68192670 LRP5 -0.58 -6.53 -0.33 2.38e-10 Total body bone mineral density (age 45-60); LIHC cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.59 -0.46 1.93e-19 Bipolar disorder; LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg23978390 chr7:1156363 C7orf50 0.57 8.92 0.43 2.78e-17 Longevity;Endometriosis; LIHC cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg11301795 chr4:187892539 NA -0.27 -7.11 -0.36 6.9e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs80282103 0.618 rs11818314 chr10:1148157 G/C cg08668510 chr10:1095578 IDI1 0.62 6.07 0.31 3.45e-9 Glomerular filtration rate (creatinine); LIHC cis rs2439831 1.000 rs561863 chr15:43761352 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.83 0.43 5.6e-17 Lung cancer in ever smokers; LIHC cis rs17253792 0.822 rs10483650 chr14:56145312 A/G cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC cis rs858239 0.600 rs6961406 chr7:23134891 C/T cg23682824 chr7:23144976 KLHL7 0.42 6.29 0.32 9.59e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs249954 0.512 rs7588 chr16:23681165 G/A cg01460202 chr16:23706506 ERN2 0.35 5.77 0.3 1.76e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs7520050 0.966 rs6675726 chr1:46560643 A/G cg03146154 chr1:46216737 IPP -0.37 -6.18 -0.32 1.87e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6089584 0.888 rs6061979 chr20:60617141 C/G cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs1385374 0.858 rs10847697 chr12:129299385 C/T cg09035930 chr12:129282057 SLC15A4 -0.47 -5.75 -0.3 1.93e-8 Systemic lupus erythematosus; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13985271 chr9:97140681 HIATL1 0.46 6.37 0.33 6.04e-10 Pancreatic cancer; LIHC cis rs9916302 0.904 rs602282 chr17:37433021 C/T cg00129232 chr17:37814104 STARD3 -0.4 -6.4 -0.33 5.02e-10 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg07424592 chr7:64974309 NA 0.75 8.5 0.42 5.89e-16 Diabetic kidney disease; LIHC cis rs919433 0.714 rs2333855 chr2:198200213 T/G cg10820045 chr2:198174542 NA -0.56 -9.1 -0.44 7.5e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6466055 0.777 rs10277120 chr7:104834417 A/T cg04380332 chr7:105027541 SRPK2 0.34 6.49 0.33 3.02e-10 Schizophrenia; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11102324 chr15:49658865 C15orf33 0.4 6.04 0.31 4.04e-9 Bilirubin levels; LIHC cis rs77637988 0.578 rs12328506 chr2:48623184 C/T cg15846641 chr2:48541264 FOXN2 0.54 7.14 0.36 5.48e-12 Joint mobility (Beighton score); LIHC cis rs2760061 0.569 rs621631 chr1:228114728 A/G cg02753203 chr1:228287806 NA -0.48 -7.48 -0.37 6.34e-13 Diastolic blood pressure; LIHC cis rs807029 0.577 rs701834 chr10:102761801 C/T cg17130504 chr10:102756923 LZTS2 0.54 7.18 0.36 4.29e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs8062405 1.000 rs62037371 chr16:28890131 C/A cg07451762 chr16:28383216 NA 0.32 5.96 0.31 6.31e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2304069 0.954 rs10045945 chr5:149419297 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.88 11.02 0.51 2.2e-24 HIV-1 control; LIHC cis rs780094 0.585 rs7586601 chr2:27584666 A/G cg22903471 chr2:27725779 GCKR -0.47 -7.85 -0.39 5.33e-14 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs12980942 0.872 rs12985339 chr19:41801756 A/T cg25627403 chr19:41769009 HNRNPUL1 -0.54 -6.67 -0.34 1.02e-10 Coronary artery disease; LIHC cis rs909341 0.537 rs6089971 chr20:62385846 G/A cg14758556 chr20:62440591 NA 0.42 6.61 0.34 1.51e-10 Atopic dermatitis; LIHC cis rs7264396 1.000 rs224415 chr20:34135629 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.38 -6.69 -0.34 9e-11 Total cholesterol levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02711976 chr1:36023590 NCDN;KIAA0319L 0.51 6.65 0.34 1.17e-10 Lung function (FEV1/FVC); LIHC cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg18876405 chr7:65276391 NA 0.55 9.4 0.45 7.97e-19 Aortic root size; LIHC cis rs2228479 0.702 rs11076620 chr16:89831520 A/T cg19635926 chr16:89946313 TCF25 0.48 6.17 0.32 1.97e-9 Skin colour saturation; LIHC cis rs8017423 0.647 rs1958345 chr14:90823770 T/C cg04374321 chr14:90722782 PSMC1 -0.49 -7.26 -0.37 2.56e-12 Mortality in heart failure; LIHC trans rs2832191 0.716 rs1984012 chr21:30392472 T/C cg14791747 chr16:20752902 THUMPD1 -0.48 -6.74 -0.34 6.59e-11 Dental caries; LIHC cis rs9818758 0.505 rs11716159 chr3:49631585 G/A cg00383909 chr3:49044727 WDR6 0.82 6.42 0.33 4.69e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs12478296 0.685 rs35577962 chr2:242993575 A/G cg06360820 chr2:242988706 NA -0.84 -12.85 -0.57 4.07e-31 Obesity-related traits; LIHC trans rs11098499 0.865 rs1112817 chr4:120297800 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs7647973 1.000 rs11710434 chr3:49346130 T/C cg07636037 chr3:49044803 WDR6 0.51 6.23 0.32 1.38e-9 Menarche (age at onset); LIHC cis rs2806561 0.765 rs2776815 chr1:23510584 C/T cg12483005 chr1:23474871 LUZP1 -0.46 -7.22 -0.36 3.44e-12 Height; LIHC cis rs9583531 0.689 rs2165418 chr13:111379365 G/T cg15841412 chr13:111365552 ING1 -0.5 -6.3 -0.32 9.41e-10 Coronary artery disease; LIHC trans rs116095464 0.558 rs61492827 chr5:225774 A/G cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs1559088 0.948 rs12608825 chr19:33581219 C/T cg17764715 chr19:33622953 WDR88 -0.46 -6.78 -0.34 5.43e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9814567 1.000 rs4572812 chr3:134291177 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.14 0.32 2.3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1707322 0.627 rs3014213 chr1:46045522 T/C cg03146154 chr1:46216737 IPP -0.55 -8.77 -0.43 8.47e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1801251 1.000 rs67013068 chr2:233608253 G/C cg08000102 chr2:233561755 GIGYF2 0.76 11.41 0.52 9.26e-26 Coronary artery disease; LIHC cis rs11122272 0.735 rs2749705 chr1:231526696 C/T cg06096015 chr1:231504339 EGLN1 0.47 8.57 0.42 3.57e-16 Hemoglobin concentration; LIHC cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg12310025 chr6:25882481 NA -0.44 -6.67 -0.34 1.03e-10 Height; LIHC cis rs425277 1.000 rs425277 chr1:2069172 C/T cg24578937 chr1:2090814 PRKCZ 0.49 8.61 0.42 2.69e-16 Height; LIHC cis rs7727544 0.684 rs272849 chr5:131690241 A/G cg07395648 chr5:131743802 NA -0.3 -6.35 -0.32 6.69e-10 Blood metabolite levels; LIHC cis rs4671400 0.571 rs28480287 chr2:61489289 G/C cg14146966 chr2:61757674 XPO1 -0.36 -5.74 -0.3 2.1e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs10779751 1.000 rs12730522 chr1:11284091 G/A cg08854313 chr1:11322531 MTOR 0.87 15.75 0.65 2.09e-42 Body mass index; LIHC cis rs829883 0.604 rs249841 chr12:98871743 A/G cg23471612 chr12:98897216 NA 0.3 5.84 0.3 1.21e-8 Colorectal adenoma (advanced); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg13888710 chr4:39699558 UBE2K -0.48 -6.9 -0.35 2.56e-11 Immature fraction of reticulocytes; LIHC cis rs7911264 1.000 rs10882100 chr10:94460687 C/G cg25506282 chr10:94462361 NA 0.42 7.29 0.37 2.22e-12 Inflammatory bowel disease; LIHC cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg05590025 chr7:65112418 INTS4L2 -0.63 -6.91 -0.35 2.35e-11 Diabetic kidney disease; LIHC cis rs4803468 1.000 rs2241710 chr19:41912092 G/C cg14132834 chr19:41945861 ATP5SL -0.43 -6.34 -0.32 7.13e-10 Height; LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg08219700 chr8:58056026 NA 0.52 7.12 0.36 6.34e-12 Developmental language disorder (linguistic errors); LIHC trans rs4843747 0.573 rs7499959 chr16:88110422 C/G cg26811252 chr16:29126840 RRN3P2 0.4 6.77 0.34 5.69e-11 Menopause (age at onset); LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg26354017 chr1:205819088 PM20D1 0.76 11.26 0.52 3.09e-25 Menarche (age at onset); LIHC cis rs523522 0.962 rs2233676 chr12:120933607 G/A cg27279351 chr12:120934652 DYNLL1 0.67 12.05 0.55 3.99e-28 High light scatter reticulocyte count; LIHC cis rs4727027 0.933 rs4727028 chr7:148874666 A/G cg23583168 chr7:148888333 NA 0.73 10.6 0.5 7e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs68170813 0.559 rs76534758 chr7:106963262 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.76 -0.3 1.9e-8 Coronary artery disease; LIHC cis rs3761218 0.866 rs579111 chr20:3763872 T/C cg25011176 chr20:3776985 CDC25B -0.45 -5.89 -0.3 9.12e-9 Bipolar disorder; LIHC cis rs10540 1.000 rs78520676 chr11:517173 G/A cg03352830 chr11:487213 PTDSS2 0.79 6.39 0.33 5.48e-10 Body mass index; LIHC cis rs249954 0.512 rs42873 chr16:23694732 C/G cg09867953 chr16:23706666 ERN2 0.34 5.86 0.3 1.11e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9916302 0.904 rs8065963 chr17:37681332 C/T cg15445000 chr17:37608096 MED1 0.38 5.83 0.3 1.26e-8 Glomerular filtration rate (creatinine); LIHC cis rs10744422 1.000 rs2292135 chr12:123334075 G/A cg25930673 chr12:123319894 HIP1R -0.93 -12.27 -0.55 6.56e-29 Schizophrenia; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.73 13.08 0.58 5.81e-32 Prudent dietary pattern; LIHC cis rs9640161 0.702 rs3735175 chr7:150020457 C/T cg21361702 chr7:150065534 REPIN1 0.46 6.24 0.32 1.3e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs9942416 0.517 rs116509898 chr5:74994361 C/T cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg00280220 chr17:61926910 NA 0.41 6.72 0.34 7.41e-11 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07387570 chr22:46663686 TTC38 0.41 6.75 0.34 6.29e-11 Cognitive function; LIHC cis rs611744 0.805 rs396149 chr8:109108740 A/C cg21045802 chr8:109455806 TTC35 0.49 8.43 0.41 9.51e-16 Dupuytren's disease; LIHC cis rs9303401 0.659 rs62083410 chr17:56964386 T/C cg25039879 chr17:56429692 SUPT4H1 0.79 8.95 0.44 2.32e-17 Cognitive test performance; LIHC cis rs1707322 0.647 rs6686944 chr1:46156308 G/T cg03146154 chr1:46216737 IPP 0.58 9.88 0.47 2.04e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg12310025 chr6:25882481 NA 0.88 12.2 0.55 1.13e-28 Blood metabolite levels; LIHC cis rs2204008 0.805 rs11180825 chr12:38242916 G/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.56e-8 Bladder cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01194468 chr9:33264774 SUGT1P1;CHMP5;BAG1 0.43 6.05 0.31 3.75e-9 Pancreatic cancer; LIHC cis rs4820294 0.547 rs62236743 chr22:38096053 T/C cg26138144 chr22:38071188 LGALS1 0.72 10.53 0.49 1.17e-22 Fat distribution (HIV); LIHC cis rs9916302 0.904 rs6503506 chr17:37524653 C/A cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.46e-34 Glomerular filtration rate (creatinine); LIHC cis rs2067615 0.599 rs3759310 chr12:107166122 C/G cg15890332 chr12:107067104 RFX4 0.26 6.04 0.31 3.96e-9 Heart rate; LIHC cis rs9303280 0.806 rs13380815 chr17:38027583 A/G cg11212589 chr17:38028394 ZPBP2 0.35 7.13 0.36 5.88e-12 Self-reported allergy; LIHC cis rs9457247 0.508 rs6941355 chr6:167506238 A/G cg23791538 chr6:167370224 RNASET2 -0.53 -9.04 -0.44 1.21e-17 Crohn's disease; LIHC cis rs12579753 0.789 rs1343933 chr12:82123301 A/C cg07988820 chr12:82153109 PPFIA2 -0.47 -5.86 -0.3 1.09e-8 Resting heart rate; LIHC cis rs757081 0.608 rs214938 chr11:17188516 C/T cg15432903 chr11:17409602 KCNJ11 -0.42 -5.81 -0.3 1.44e-8 Systolic blood pressure; LIHC cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg11764359 chr7:65958608 NA 0.6 6.34 0.32 7.29e-10 Diabetic kidney disease; LIHC cis rs904251 0.523 rs2797794 chr6:37480604 T/C cg08126542 chr6:37504118 NA -0.37 -6.3 -0.32 9.37e-10 Cognitive performance; LIHC cis rs2180341 0.924 rs877661 chr6:127587915 T/G cg24812749 chr6:127587940 RNF146 1.03 15.41 0.64 4.8e-41 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05744073 chr17:1953268 MIR132 0.45 6.72 0.34 7.54e-11 Pancreatic cancer; LIHC cis rs11711311 1.000 rs3806641 chr3:113465761 T/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.49 9.49 0.46 4.07e-19 IgG glycosylation; LIHC cis rs7727544 0.684 rs2516788 chr5:131715565 G/C cg07395648 chr5:131743802 NA 0.31 6.49 0.33 3e-10 Blood metabolite levels; LIHC cis rs10911232 0.507 rs10797829 chr1:183033228 C/T ch.1.3577855R chr1:183094577 LAMC1 -0.61 -10.59 -0.5 7.16e-23 Hypertriglyceridemia; LIHC cis rs12824058 0.737 rs11060829 chr12:130814996 G/T cg24229701 chr12:130821962 PIWIL1 0.44 6.73 0.34 7.1e-11 Menopause (age at onset); LIHC cis rs1055129 0.681 rs7221792 chr17:73834690 T/G cg19302996 chr17:73780495 UNK -0.6 -9.51 -0.46 3.52e-19 White matter hyperintensity burden; LIHC cis rs7582720 1.000 rs72932777 chr2:203689914 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.83 0.3 1.27e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20925434 chr21:35014276 ITSN1;CRYZL1 -0.52 -6.18 -0.32 1.84e-9 Systolic blood pressure; LIHC cis rs4474465 0.833 rs10793320 chr11:78217460 G/A cg27205649 chr11:78285834 NARS2 0.4 6.26 0.32 1.17e-9 Alzheimer's disease (survival time); LIHC cis rs4718428 0.705 rs13227468 chr7:66433563 T/C cg18252515 chr7:66147081 NA -0.71 -9.63 -0.46 1.37e-19 Corneal structure; LIHC cis rs1865760 0.927 rs6915834 chr6:25935427 A/C cg17691542 chr6:26056736 HIST1H1C 0.4 6.0 0.31 4.97e-9 Height; LIHC cis rs12644436 0.560 rs10013459 chr4:88781743 A/G cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg00091569 chr3:40428383 ENTPD3 0.38 6.38 0.33 5.64e-10 Renal cell carcinoma; LIHC cis rs6598955 0.724 rs7547520 chr1:26592310 C/T cg00852783 chr1:26633632 UBXN11 0.51 8.5 0.42 6e-16 Obesity-related traits; LIHC cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.1 17.12 0.68 6.77e-48 Gut microbiome composition (summer); LIHC cis rs6752107 1.000 rs3792112 chr2:234176609 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.31 0.41 2.3e-15 Crohn's disease;Inflammatory bowel disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22535057 chr3:9542104 LHFPL4 0.47 6.61 0.34 1.51e-10 Lung function (FEV1/FVC); LIHC cis rs7772486 0.806 rs7740785 chr6:146171299 C/A cg23711669 chr6:146136114 FBXO30 0.6 11.02 0.51 2.25e-24 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23243902 chr11:117049849 SIDT2 0.53 7.26 0.37 2.55e-12 Lung function (FEV1/FVC); LIHC cis rs896854 1.000 rs896854 chr8:95960511 T/C cg09323728 chr8:95962352 TP53INP1 -0.35 -7.8 -0.39 7.55e-14 Type 2 diabetes; LIHC cis rs12477438 0.520 rs8179690 chr2:99795300 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.84 -14.46 -0.62 2.67e-37 Chronic sinus infection; LIHC cis rs6752107 1.000 rs6738490 chr2:234161583 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.56 8.59 0.42 3.08e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs644799 0.544 rs1527450 chr11:95467777 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.76 11.75 0.54 5.28e-27 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs826838 0.935 rs1684406 chr12:39127265 A/G cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.4e-8 Heart rate; LIHC cis rs589448 0.967 rs634512 chr12:69754012 C/T cg19645103 chr12:69753606 YEATS4 -0.4 -5.92 -0.3 7.74e-9 Cerebrospinal fluid biomarker levels; LIHC trans rs9747201 0.894 rs9944398 chr17:80177439 A/G cg07393940 chr7:158741817 NA 0.54 6.25 0.32 1.21e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7904368 0.806 rs45495501 chr10:16861476 G/A cg14835575 chr10:16859367 RSU1 0.67 9.17 0.44 4.49e-18 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs4268898 0.760 rs11676939 chr2:24479057 C/T cg06627628 chr2:24431161 ITSN2 0.47 6.7 0.34 8.53e-11 Asthma; LIHC cis rs4746818 0.818 rs10823302 chr10:70895418 G/T cg11621586 chr10:70884670 VPS26A 0.88 14.57 0.62 1e-37 Left atrial antero-posterior diameter; LIHC cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg25072359 chr17:41440525 NA 0.37 5.83 0.3 1.3e-8 Menopause (age at onset); LIHC cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg21724239 chr8:58056113 NA 0.49 6.46 0.33 3.61e-10 Developmental language disorder (linguistic errors); LIHC cis rs10276381 1.000 rs10260837 chr7:28181129 C/T cg23620719 chr7:28220237 JAZF1 0.63 7.87 0.39 4.72e-14 Crohn's disease; LIHC cis rs10791323 0.569 rs10750541 chr11:133713189 A/C cg06766960 chr11:133703094 NA 0.67 11.12 0.52 9.84e-25 Childhood ear infection; LIHC cis rs10489202 1.000 rs7520232 chr1:168011995 T/C cg24449463 chr1:168025552 DCAF6 -0.51 -6.51 -0.33 2.68e-10 Schizophrenia; LIHC cis rs875971 0.571 rs78668714 chr7:65939451 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.34 6.78 0.34 5.43e-11 Aortic root size; LIHC cis rs739401 0.611 rs7109088 chr11:3027485 G/T cg08508325 chr11:3079039 CARS -0.31 -6.77 -0.34 5.72e-11 Longevity; LIHC cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs473651 0.503 rs515342 chr2:239367296 A/G cg01753270 chr2:239240285 TRAF3IP1 -0.43 -8.1 -0.4 9.89e-15 Multiple system atrophy; LIHC cis rs2637266 0.905 rs2579772 chr10:78406555 A/G cg18941641 chr10:78392320 NA 0.28 6.18 0.32 1.79e-9 Pulmonary function; LIHC cis rs4243830 1.000 rs11811007 chr1:6584657 T/C cg22792644 chr1:6614718 TAS1R1;NOL9 0.78 7.63 0.38 2.3e-13 Body mass index; LIHC cis rs875971 0.767 rs61348003 chr7:66005934 C/T cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.38e-11 Aortic root size; LIHC cis rs56011263 0.687 rs73221103 chr4:706740 T/C cg20735989 chr4:730612 PCGF3 -0.66 -8.72 -0.43 1.26e-16 White blood cell count; LIHC cis rs72781680 1.000 rs72781665 chr2:24223086 G/A cg08917208 chr2:24149416 ATAD2B 0.83 7.57 0.38 3.4e-13 Lymphocyte counts; LIHC cis rs8114671 0.562 rs6087641 chr20:33467717 T/C cg07148914 chr20:33460835 GGT7 0.63 9.57 0.46 2.29e-19 Height; LIHC cis rs8180040 0.726 rs61729713 chr3:47027192 A/G cg27129171 chr3:47204927 SETD2 -0.57 -9.24 -0.45 2.63e-18 Colorectal cancer; LIHC cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg03264133 chr6:25882463 NA -0.47 -7.2 -0.36 3.77e-12 Height; LIHC cis rs7572733 0.555 rs6729473 chr2:198763928 G/A cg03934865 chr2:198174659 NA 0.47 6.74 0.34 6.87e-11 Dermatomyositis; LIHC cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.29 -5.86 -0.3 1.07e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs28374715 1.000 rs28374715 chr15:41563950 A/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -11.13 -0.52 9.45e-25 Ulcerative colitis; LIHC cis rs10883723 0.810 rs12162 chr10:104240498 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 10.58 0.5 7.85e-23 Allergic disease (asthma, hay fever or eczema); LIHC cis rs67311347 0.955 rs6599100 chr3:40447362 C/T cg09455208 chr3:40491958 NA 0.32 6.37 0.33 6.09e-10 Renal cell carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24549639 chr12:69201477 MDM2 0.45 6.37 0.33 6.14e-10 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs958550 chr7:65635679 C/T cg18252515 chr7:66147081 NA 1.17 14.97 0.63 2.61e-39 Diabetic kidney disease; LIHC cis rs916888 0.821 rs199513 chr17:44856932 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.68 -6.77 -0.34 5.61e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs12477438 0.765 rs13406288 chr2:99589585 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.7 -10.39 -0.49 3.57e-22 Chronic sinus infection; LIHC cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs13108904 0.539 rs13135102 chr4:1330983 A/C cg05665937 chr4:1216051 CTBP1 0.44 5.87 0.3 1.04e-8 Obesity-related traits; LIHC cis rs12701220 0.894 rs8591 chr7:1036799 C/T cg26769984 chr7:1090371 C7orf50 0.61 7.69 0.38 1.53e-13 Bronchopulmonary dysplasia; LIHC cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.5 0.38 5.37e-13 Electroencephalogram traits; LIHC cis rs9814567 1.000 rs1880377 chr3:134270468 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs311392 1.000 rs311392 chr8:55084782 A/G cg11783602 chr8:55087084 NA -0.29 -5.73 -0.3 2.24e-8 Pelvic organ prolapse (moderate/severe); LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg00280220 chr17:61926910 NA 0.42 6.83 0.35 3.82e-11 Prudent dietary pattern; LIHC cis rs12950390 0.853 rs8071192 chr17:45856141 A/G cg03474202 chr17:45855739 NA -0.34 -5.98 -0.31 5.53e-9 IgG glycosylation; LIHC cis rs8067354 0.789 rs1292068 chr17:57929319 T/C cg02344993 chr17:57696989 CLTC 0.54 8.68 0.42 1.67e-16 Hemoglobin concentration; LIHC cis rs7729447 0.813 rs10941022 chr5:32691416 C/T cg16267343 chr5:32710456 NPR3 0.46 5.73 0.3 2.19e-8 Blood pressure; LIHC cis rs10504229 0.679 rs16921623 chr8:58039473 G/C cg20607798 chr8:58055168 NA 0.46 6.3 0.32 9.07e-10 Developmental language disorder (linguistic errors); LIHC cis rs4689592 0.503 rs3857180 chr4:7073899 T/G cg02503808 chr4:7069936 GRPEL1 -0.8 -10.95 -0.51 3.97e-24 Monocyte percentage of white cells; LIHC cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg10862848 chr6:42927986 GNMT -0.26 -6.31 -0.32 8.41e-10 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25029360 chr8:141646502 EIF2C2 -0.53 -6.66 -0.34 1.12e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs17401966 0.838 rs61775885 chr1:10281445 T/C cg19773385 chr1:10388646 KIF1B -0.39 -7.02 -0.35 1.23e-11 Hepatocellular carcinoma; LIHC cis rs763121 0.853 rs5750659 chr22:39068789 T/C cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.59 0.62 8.17e-38 Prudent dietary pattern; LIHC cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg11663144 chr21:46675770 NA -0.32 -5.93 -0.31 7.44e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.35 0.41 1.66e-15 Platelet count; LIHC cis rs11676348 0.783 rs4674252 chr2:218984478 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.15 -0.32 2.21e-9 Ulcerative colitis; LIHC cis rs7618501 0.699 rs2777888 chr3:49898000 A/G cg24110177 chr3:50126178 RBM5 -0.53 -8.22 -0.41 4.25e-15 Intelligence (multi-trait analysis); LIHC cis rs9614461 0.826 rs9614649 chr22:45746097 C/A cg18180155 chr22:45809454 SMC1B;RIBC2 0.54 6.01 0.31 4.87e-9 Tonsillectomy; LIHC cis rs7296418 0.630 rs7974099 chr12:123771475 A/G cg05973401 chr12:123451056 ABCB9 0.42 6.38 0.33 5.89e-10 Platelet count; LIHC cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.94 -0.31 7.07e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7703051 0.520 rs13354746 chr5:74619132 C/T cg00601450 chr5:74908170 NA 0.47 6.56 0.33 2.03e-10 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC trans rs8073060 0.586 rs2523116 chr17:34025460 T/C cg19694781 chr19:47549865 TMEM160 -1.22 -13.08 -0.58 5.37e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs986417 0.818 rs1950311 chr14:60989604 A/C cg27398547 chr14:60952738 C14orf39 0.74 8.26 0.41 3.24e-15 Gut microbiota (bacterial taxa); LIHC cis rs10832963 0.924 rs10500834 chr11:18638712 A/T cg09201001 chr11:18656081 SPTY2D1 0.94 17.62 0.69 6.38e-50 Breast cancer; LIHC cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg10896456 chr17:42255109 ASB16;C17orf65 0.53 9.78 0.47 4.54e-20 Total body bone mineral density; LIHC cis rs6502050 0.871 rs8066970 chr17:80076051 T/C cg11859384 chr17:80120422 CCDC57 0.42 5.74 0.3 2.07e-8 Life satisfaction; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02916409 chr16:2510063 C16orf59 0.45 6.35 0.32 6.92e-10 Lung function (FEV1/FVC); LIHC cis rs4819052 0.851 rs875621 chr21:46682295 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.84 0.39 5.64e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1348850 0.561 rs1838890 chr2:178410938 C/A cg27490568 chr2:178487706 NA 0.92 10.26 0.49 1.01e-21 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg20818283 chr2:191399100 TMEM194B 0.46 6.25 0.32 1.23e-9 Pulse pressure; LIHC trans rs61931739 0.517 rs2636073 chr12:34063049 C/T cg26384229 chr12:38710491 ALG10B 0.43 6.04 0.31 3.94e-9 Morning vs. evening chronotype; LIHC cis rs546131 0.928 rs483976 chr11:34840167 C/G cg06937548 chr11:34938143 PDHX;APIP 0.54 7.49 0.38 5.95e-13 Lung disease severity in cystic fibrosis; LIHC cis rs11676348 0.838 rs17844697 chr2:218999255 G/A cg00012203 chr2:219082015 ARPC2 -0.46 -5.93 -0.31 7.4e-9 Ulcerative colitis; LIHC cis rs2963155 0.518 rs865482 chr5:142640317 C/A cg17617527 chr5:142782415 NR3C1 0.94 10.62 0.5 5.85e-23 Breast cancer; LIHC cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg18654377 chr3:49208889 KLHDC8B -0.5 -5.96 -0.31 6.35e-9 Menarche (age at onset); LIHC cis rs6504950 0.800 rs17745183 chr17:53013595 G/T cg10237252 chr17:52977213 TOM1L1 -0.35 -6.16 -0.32 2.03e-9 Breast cancer; LIHC cis rs2710642 0.962 rs2058567 chr2:63091426 T/C cg17519650 chr2:63277830 OTX1 0.45 7.02 0.35 1.19e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs11252926 0.599 rs11252213 chr10:454694 C/T cg16346588 chr10:242978 ZMYND11 0.39 5.97 0.31 5.99e-9 Psychosis in Alzheimer's disease; LIHC cis rs9790314 0.875 rs336568 chr3:161072763 G/C cg03342759 chr3:160939853 NMD3 -0.67 -9.16 -0.44 4.99e-18 Morning vs. evening chronotype; LIHC cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg02931644 chr1:25747376 RHCE -0.33 -7.06 -0.36 9.29e-12 Erythrocyte sedimentation rate; LIHC cis rs4808199 0.948 rs2074301 chr19:19381715 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.55 7.84 0.39 5.89e-14 Nonalcoholic fatty liver disease; LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg26338869 chr17:61819248 STRADA 0.52 6.98 0.35 1.54e-11 Height; LIHC cis rs858239 0.600 rs10256524 chr7:23144947 T/C cg23682824 chr7:23144976 KLHL7 0.47 7.04 0.36 1.08e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg02951883 chr7:2050386 MAD1L1 -0.62 -9.68 -0.46 9.65e-20 Bipolar disorder and schizophrenia; LIHC cis rs2404602 0.647 rs116505114 chr15:77074794 T/C cg23625390 chr15:77176239 SCAPER -0.56 -9.54 -0.46 2.86e-19 Blood metabolite levels; LIHC cis rs72781680 0.898 rs72786276 chr2:24062566 G/A cg08917208 chr2:24149416 ATAD2B 0.99 8.7 0.43 1.39e-16 Lymphocyte counts; LIHC cis rs4713118 0.869 rs9295743 chr6:27715102 G/C cg20933634 chr6:27740509 NA 0.46 6.07 0.31 3.32e-9 Parkinson's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07832834 chr1:2457954 PANK4 0.52 6.59 0.34 1.68e-10 Lung function (FEV1/FVC); LIHC cis rs8180040 0.726 rs4682842 chr3:46982773 C/G cg27129171 chr3:47204927 SETD2 -0.64 -10.74 -0.5 2.22e-23 Colorectal cancer; LIHC cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs1550582 0.662 rs7812708 chr8:135500832 C/T cg09855544 chr8:135498122 ZFAT 0.38 6.13 0.31 2.44e-9 Educational attainment; LIHC cis rs1538970 0.924 rs4660858 chr1:45936351 G/A cg24296786 chr1:45957014 TESK2 -0.52 -7.6 -0.38 2.87e-13 Platelet count; LIHC cis rs919433 0.617 rs700643 chr2:198601370 A/G cg00792783 chr2:198669748 PLCL1 0.45 6.52 0.33 2.57e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg11062466 chr8:58055876 NA 0.52 7.12 0.36 6.28e-12 Developmental language disorder (linguistic errors); LIHC cis rs17826219 0.568 rs9907834 chr17:29154013 G/A cg14067834 chr17:29058358 SUZ12P 0.69 6.69 0.34 9.41e-11 Body mass index; LIHC cis rs7208859 0.573 rs73277974 chr17:29189869 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1568889 1.000 rs12790932 chr11:28046189 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.99 0.35 1.48e-11 Bipolar disorder; LIHC cis rs9916302 0.861 rs12150493 chr17:37586154 T/C cg07936489 chr17:37558343 FBXL20 -0.84 -13.48 -0.59 1.65e-33 Glomerular filtration rate (creatinine); LIHC cis rs9309473 0.950 rs2947860 chr2:73855386 A/G cg20560298 chr2:73613845 ALMS1 -0.52 -6.16 -0.32 2.09e-9 Metabolite levels; LIHC cis rs986417 1.000 rs10143118 chr14:61066043 G/A cg27398547 chr14:60952738 C14orf39 0.71 7.5 0.38 5.5e-13 Gut microbiota (bacterial taxa); LIHC cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg11644478 chr21:40555479 PSMG1 0.88 11.43 0.53 7.95e-26 Cognitive function; LIHC cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg06466757 chr4:1255808 NA 0.35 5.93 0.31 7.24e-9 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08862778 chr1:11322643 MTOR 0.47 7.01 0.35 1.28e-11 Pancreatic cancer; LIHC cis rs10911232 0.507 rs10911231 chr1:183051745 T/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Hypertriglyceridemia; LIHC cis rs8017423 0.904 rs11622257 chr14:90715014 C/T cg04374321 chr14:90722782 PSMC1 -0.75 -14.36 -0.61 6.1e-37 Mortality in heart failure; LIHC cis rs12477438 0.765 rs6542846 chr2:99563654 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.48 -0.38 6.16e-13 Chronic sinus infection; LIHC cis rs4423214 1.000 rs2276361 chr11:71169648 A/G cg24826892 chr11:71159390 DHCR7 0.47 6.1 0.31 2.81e-9 Vitamin D levels; LIHC cis rs6442522 0.772 rs3846127 chr3:15491527 G/C cg16303742 chr3:15540471 COLQ 0.44 7.12 0.36 6.47e-12 Uric acid levels; LIHC cis rs17376456 0.877 rs35747258 chr5:93310129 C/T cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs4808199 0.947 rs2099333 chr19:19605963 C/T cg21559469 chr19:19431446 KIAA0892;SF4 0.42 5.77 0.3 1.75e-8 Nonalcoholic fatty liver disease; LIHC cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg06634786 chr22:41940651 POLR3H -0.75 -7.71 -0.38 1.35e-13 Vitiligo; LIHC cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.6 5.86 0.3 1.11e-8 Platelet count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21983178 chr1:45120676 TMEM53 -0.41 -6.24 -0.32 1.29e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 0.755 rs4149398 chr16:28608938 C/G cg00204512 chr16:28754710 NA 0.4 6.89 0.35 2.68e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs79149102 0.579 rs7173218 chr15:75315328 A/G cg15902774 chr15:75289873 SCAMP5 0.45 6.78 0.34 5.29e-11 Lung cancer; LIHC cis rs17152411 1.000 rs7077936 chr10:126650065 C/T cg07906193 chr10:126599966 NA 0.48 7.85 0.39 5.28e-14 Height; LIHC cis rs3789045 0.729 rs12039968 chr1:204490674 C/T cg17419461 chr1:204415978 PIK3C2B -0.43 -6.62 -0.34 1.4e-10 Educational attainment (college completion); LIHC cis rs1707322 1.000 rs1707338 chr1:46511981 T/G cg06784218 chr1:46089804 CCDC17 -0.36 -6.58 -0.34 1.81e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 0.955 rs60554147 chr3:40472503 T/C cg24209194 chr3:40518798 ZNF619 0.49 7.37 0.37 1.32e-12 Renal cell carcinoma; LIHC cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg13866156 chr1:1669148 SLC35E2 -0.69 -13.53 -0.59 1.03e-33 Body mass index; LIHC cis rs75908454 1.000 rs75669960 chr6:169939060 A/G cg19338460 chr6:170058176 WDR27 -0.8 -7.48 -0.37 6.38e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs12220238 0.908 rs4746179 chr10:75940169 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.86 0.35 3.21e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs611744 0.967 rs650401 chr8:109196854 C/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs801193 0.613 rs2659900 chr7:66184443 G/C cg11764359 chr7:65958608 NA 0.83 14.78 0.62 1.42e-38 Aortic root size; LIHC trans rs7613875 0.600 rs1138536 chr3:50153356 C/T cg21659725 chr3:3221576 CRBN 0.53 7.93 0.39 3.04e-14 Body mass index; LIHC cis rs6964587 0.839 rs10808086 chr7:91447515 T/C cg17063962 chr7:91808500 NA 0.96 17.34 0.68 8.84e-49 Breast cancer; LIHC cis rs7582720 0.943 rs72932575 chr2:203866857 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.1 0.31 2.88e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2066819 1.000 rs111885088 chr12:56657216 A/C cg26714650 chr12:56694279 CS -1.38 -13.21 -0.58 1.83e-32 Psoriasis vulgaris; LIHC cis rs2859741 0.935 rs2782410 chr1:37509489 G/C cg09363841 chr1:37513479 NA -0.2 -6.34 -0.32 7.2e-10 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs2224391 1.000 rs13191012 chr6:5261292 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs427394 0.802 rs274692 chr5:6734625 C/T cg10857441 chr5:6722123 POLS -0.37 -6.37 -0.33 6.1e-10 Menopause (age at onset); LIHC cis rs7312933 0.703 rs10880268 chr12:42599122 C/T cg01256987 chr12:42539512 GXYLT1 -0.41 -6.86 -0.35 3.33e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9649213 0.593 rs13232181 chr7:97935671 C/G cg08684580 chr7:98029266 BAIAP2L1 -0.36 -5.72 -0.3 2.31e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05203659 chr16:12009378 GSPT1 0.48 6.09 0.31 3.03e-9 Lung function (FEV1/FVC); LIHC cis rs1046896 1.000 rs28485881 chr17:80690014 G/A cg02711726 chr17:80685570 FN3KRP -0.57 -11.25 -0.52 3.37e-25 Glycated hemoglobin levels; LIHC cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg03806693 chr22:41940476 POLR3H 1.09 12.73 0.57 1.19e-30 Vitiligo; LIHC cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg27170947 chr2:26402098 FAM59B -0.68 -8.4 -0.41 1.25e-15 Gut microbiome composition (summer); LIHC cis rs10870270 1.000 rs10870271 chr10:133754807 A/G cg26149184 chr10:133730230 NA -0.4 -6.16 -0.32 2.08e-9 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs903552 0.932 rs1587108 chr15:102006825 G/A cg06707286 chr15:102010195 PCSK6 -0.47 -6.64 -0.34 1.21e-10 Diabetic kidney disease; LIHC cis rs6783573 0.524 rs11130097 chr3:46620614 T/C cg21489266 chr3:46619131 LRRC2;TDGF1 -0.29 -5.74 -0.3 2.14e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs9790314 1.000 rs4370045 chr3:160943865 A/G cg04691961 chr3:161091175 C3orf57 -0.38 -6.18 -0.32 1.83e-9 Morning vs. evening chronotype; LIHC cis rs17125944 0.686 rs912861 chr14:53333290 C/G cg00686598 chr14:53173677 PSMC6 -0.75 -8.62 -0.42 2.62e-16 Alzheimer's disease (late onset); LIHC cis rs2204008 0.837 rs55962152 chr12:38234281 G/A cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs4727027 0.901 rs34201592 chr7:148842403 C/G cg23583168 chr7:148888333 NA -0.73 -10.47 -0.49 1.93e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs9393692 0.905 rs4412192 chr6:26290377 A/G cg00631329 chr6:26305371 NA 0.44 7.5 0.38 5.72e-13 Educational attainment; LIHC trans rs35110281 0.627 rs7282704 chr21:44966253 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.49 6.72 0.34 7.7e-11 Mean corpuscular volume; LIHC cis rs7106204 0.748 rs28552633 chr11:24207518 A/C ch.11.24196551F chr11:24239977 NA 0.77 9.96 0.47 1.11e-20 Response to Homoharringtonine (cytotoxicity); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08511015 chr19:11515999 RGL3 -0.37 -6.43 -0.33 4.31e-10 Calcium levels; LIHC cis rs1577917 0.740 rs9353327 chr6:86394066 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.19 -0.32 1.7e-9 Response to antipsychotic treatment; LIHC cis rs1144333 0.850 rs1146651 chr1:76273594 C/A cg10523679 chr1:76189770 ACADM -0.46 -6.73 -0.34 7.26e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs3741404 1.000 rs11603042 chr11:64003843 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.95 15.08 0.63 9.22e-40 Platelet count; LIHC cis rs3736485 0.873 rs12441759 chr15:51755033 C/A cg08986416 chr15:51914746 DMXL2 -0.39 -5.81 -0.3 1.4e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs939574 0.722 rs115402093 chr2:220096128 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.89 6.37 0.33 5.99e-10 Platelet distribution width; LIHC cis rs2228479 0.850 rs17226498 chr16:89840631 T/C cg04013166 chr16:89971882 TCF25 0.53 6.67 0.34 1.04e-10 Skin colour saturation; LIHC cis rs3770081 1.000 rs1561328 chr2:86272758 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -9.32 -0.45 1.46e-18 Facial emotion recognition (sad faces); LIHC cis rs1046896 0.627 rs7225515 chr17:80795783 C/T cg02711726 chr17:80685570 FN3KRP -0.43 -8.03 -0.4 1.61e-14 Glycated hemoglobin levels; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.97 0.8 4.54e-79 Prudent dietary pattern; LIHC cis rs7843479 0.601 rs1058486 chr8:21862551 A/G cg17168535 chr8:21777572 XPO7 0.57 10.29 0.49 8.26e-22 Mean corpuscular volume; LIHC cis rs2228479 0.717 rs9282682 chr16:89805794 A/G cg04013166 chr16:89971882 TCF25 0.46 5.73 0.3 2.2e-8 Skin colour saturation; LIHC cis rs8180040 0.620 rs6414435 chr3:47121140 A/G cg27129171 chr3:47204927 SETD2 0.56 9.35 0.45 1.21e-18 Colorectal cancer; LIHC trans rs66573146 0.831 rs56320732 chr4:6974319 G/A cg07817883 chr1:32538562 TMEM39B 1.1 9.16 0.44 5.02e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg10802521 chr3:52805072 NEK4 -0.39 -6.36 -0.33 6.63e-10 Electroencephalogram traits; LIHC cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.8 0.3 1.55e-8 Menopause (age at onset); LIHC cis rs7904368 0.806 rs7899923 chr10:16857394 G/A cg14835575 chr10:16859367 RSU1 0.64 8.81 0.43 6.33e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC trans rs2727020 0.729 rs1164685 chr11:49293660 G/A cg03929089 chr4:120376271 NA 0.81 14.37 0.61 5.58e-37 Coronary artery disease; LIHC cis rs7116495 0.609 rs567026 chr11:71769952 C/T cg10381502 chr11:71823885 C11orf51 1.08 9.2 0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs317689 0.690 rs618470 chr12:69672060 A/G cg19645103 chr12:69753606 YEATS4 -0.45 -5.98 -0.31 5.74e-9 Response to diuretic therapy; LIHC cis rs2723064 0.543 rs2080385 chr2:65292762 G/T cg05010058 chr2:65284262 CEP68 0.36 5.84 0.3 1.19e-8 Atrial fibrillation; LIHC cis rs7903847 0.667 rs11189181 chr10:99144154 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.34 -0.32 7.25e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9611565 0.592 rs28750375 chr22:41990644 A/C cg03806693 chr22:41940476 POLR3H -0.84 -9.3 -0.45 1.71e-18 Vitiligo; LIHC cis rs57502260 0.704 rs923346 chr11:68182375 T/C cg20283391 chr11:68216788 NA -0.48 -5.91 -0.3 8.35e-9 Total body bone mineral density (age 45-60); LIHC cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg24531977 chr5:56204891 C5orf35 -0.68 -9.78 -0.47 4.46e-20 Initial pursuit acceleration; LIHC cis rs6912958 0.559 rs369674 chr6:88043402 C/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.57 -10.89 -0.51 6.64e-24 Monocyte percentage of white cells; LIHC cis rs6728861 1 rs6728861 chr2:203873743 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease; LIHC trans rs8113308 0.810 rs11881650 chr19:52450139 A/C cg14959425 chr7:20447707 ITGB8 0.47 6.11 0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs6062302 0.522 rs6089929 chr20:62219679 C/T cg16989086 chr20:62203971 PRIC285 0.53 7.6 0.38 2.84e-13 Glioblastoma; LIHC cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg08859206 chr1:53392774 SCP2 0.36 5.98 0.31 5.73e-9 Monocyte count; LIHC cis rs7674212 0.512 rs2720462 chr4:104056210 T/G cg16532752 chr4:104119610 CENPE -0.43 -6.68 -0.34 9.82e-11 Type 2 diabetes; LIHC cis rs1552244 0.515 rs67342818 chr3:10166406 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.34 -0.32 7.09e-10 Bipolar disorder and schizophrenia; LIHC cis rs912057 0.671 rs1294425 chr6:6744292 G/A cg06612196 chr6:6737390 NA 0.51 9.77 0.47 4.85e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs6500602 0.702 rs11076835 chr16:4549618 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 6.14 0.32 2.24e-9 Schizophrenia; LIHC cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.58 0.34 1.76e-10 Bipolar disorder; LIHC cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg14262678 chr6:151773367 RMND1;C6orf211 0.67 10.99 0.51 2.83e-24 Menarche (age at onset); LIHC cis rs986417 0.681 rs1254329 chr14:60912870 G/A cg27398547 chr14:60952738 C14orf39 -0.81 -9.56 -0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs9534288 0.912 rs9526135 chr13:46624992 G/C cg15192986 chr13:46630673 CPB2 -0.57 -8.57 -0.42 3.55e-16 Blood protein levels; LIHC cis rs6952808 0.564 rs73038441 chr7:2139286 T/C cg02951883 chr7:2050386 MAD1L1 -0.64 -10.51 -0.49 1.38e-22 Bipolar disorder and schizophrenia; LIHC cis rs8114671 0.586 rs734111 chr20:33533736 A/C cg07148914 chr20:33460835 GGT7 0.65 9.85 0.47 2.57e-20 Height; LIHC cis rs798554 0.679 rs1636249 chr7:2884283 T/G cg04166393 chr7:2884313 GNA12 0.52 8.28 0.41 2.9e-15 Height; LIHC cis rs1348850 0.651 rs1901824 chr2:178225466 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.79 12.25 0.55 7.55e-29 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12477438 0.765 rs1453564 chr2:99564428 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.42 -0.49 2.81e-22 Chronic sinus infection; LIHC cis rs3770081 0.793 rs60719866 chr2:86284378 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.96 -11.41 -0.53 9.09e-26 Facial emotion recognition (sad faces); LIHC cis rs9811920 0.638 rs793503 chr3:99588070 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.49 -6.91 -0.35 2.37e-11 Axial length; LIHC cis rs12368653 0.641 rs7311632 chr12:58086340 A/C cg12615879 chr12:58013172 SLC26A10 0.36 7.04 0.36 1.04e-11 Multiple sclerosis; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg21747090 chr2:27597821 SNX17 -0.4 -5.86 -0.3 1.06e-8 Total body bone mineral density; LIHC cis rs4474465 1.000 rs908003 chr11:78190340 A/T cg02023728 chr11:77925099 USP35 0.33 5.96 0.31 6.39e-9 Alzheimer's disease (survival time); LIHC trans rs1005277 0.579 rs1780133 chr10:38499509 T/C cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC trans rs2352908 1.000 rs1890724 chr14:49442749 A/T cg16568472 chr20:3190600 ITPA -0.44 -6.04 -0.31 3.95e-9 Social communication problems; LIHC cis rs13191362 0.507 rs2849524 chr6:163127070 C/T cg06582575 chr6:163149167 PACRG;PARK2 -0.52 -6.0 -0.31 5.11e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs35110281 0.782 rs1454651 chr21:45012476 A/G cg04455712 chr21:45112962 RRP1B 0.49 8.11 0.4 9.31e-15 Mean corpuscular volume; LIHC cis rs2816062 0.710 rs2816052 chr1:18895536 T/C cg18795169 chr1:18902165 NA -0.8 -18.23 -0.7 2.41e-52 Urate levels in lean individuals; LIHC cis rs2073499 0.935 rs74398439 chr3:50331927 C/T cg03645007 chr3:50255295 SLC38A3 0.53 7.09 0.36 7.83e-12 Schizophrenia; LIHC cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg02931644 chr1:25747376 RHCE 0.34 7.24 0.36 2.99e-12 Erythrocyte sedimentation rate; LIHC cis rs9911578 0.842 rs12450766 chr17:56832965 G/C cg12560992 chr17:57184187 TRIM37 -0.82 -12.75 -0.57 1.02e-30 Intelligence (multi-trait analysis); LIHC cis rs2637030 0.559 rs187659 chr5:52916018 G/A cg06476337 chr5:52856530 NDUFS4 0.43 6.81 0.35 4.3e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs1434579 0.865 rs12978546 chr19:44945947 C/A cg15540054 chr19:45004280 ZNF180 0.57 7.9 0.39 3.88e-14 Tuberculosis; LIHC cis rs2228479 0.850 rs17226519 chr16:89839854 T/C cg14709524 chr16:89940631 TCF25 0.47 5.79 0.3 1.58e-8 Skin colour saturation; LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs992157 0.835 rs6729058 chr2:219148369 G/A cg00012203 chr2:219082015 ARPC2 -0.82 -13.08 -0.58 5.49e-32 Colorectal cancer; LIHC cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7715806 0.500 rs34355 chr5:74959970 G/A cg08253296 chr5:74907592 NA -0.51 -6.52 -0.33 2.49e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs709400 0.628 rs12889639 chr14:103860206 G/A cg26031613 chr14:104095156 KLC1 -0.7 -9.09 -0.44 7.94e-18 Body mass index; LIHC cis rs875971 0.798 rs12698522 chr7:65967341 T/C cg11764359 chr7:65958608 NA 0.78 13.52 0.59 1.17e-33 Aortic root size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06989074 chr11:68133177 LRP5 -0.4 -6.67 -0.34 1.01e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs208515 0.525 rs1484577 chr6:66688397 A/G cg07460842 chr6:66804631 NA 0.78 8.99 0.44 1.67e-17 Exhaled nitric oxide levels; LIHC cis rs1506636 1.000 rs646753 chr7:123401237 G/T cg03229431 chr7:123269106 ASB15 0.6 12.01 0.54 5.6e-28 Plateletcrit;Platelet count; LIHC cis rs3820068 0.603 rs72647120 chr1:15956769 G/T cg17385448 chr1:15911702 AGMAT 0.34 5.98 0.31 5.77e-9 Systolic blood pressure; LIHC cis rs9916302 0.904 rs11078910 chr17:37671269 G/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.37 -0.59 4.35e-33 Glomerular filtration rate (creatinine); LIHC trans rs2727020 0.576 rs12293522 chr11:49558425 T/A cg18944383 chr4:111397179 ENPEP 0.25 6.34 0.32 7.08e-10 Coronary artery disease; LIHC trans rs4650994 1.000 rs10913572 chr1:178526718 C/T cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1941023 0.584 rs7935082 chr11:60155000 T/C cg08716584 chr11:60157161 MS4A7 -0.37 -8.43 -0.41 9.81e-16 Congenital heart disease (maternal effect); LIHC cis rs7208859 0.673 rs9894876 chr17:29182020 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1577917 1.000 rs36096931 chr6:86693134 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.47 -0.33 3.39e-10 Response to antipsychotic treatment; LIHC trans rs11098499 0.954 rs9993199 chr4:120392873 A/G cg25214090 chr10:38739885 LOC399744 -0.53 -8.85 -0.43 4.79e-17 Corneal astigmatism; LIHC cis rs10791323 0.604 rs2851116 chr11:133705759 G/A cg06766960 chr11:133703094 NA -0.66 -10.88 -0.51 6.89e-24 Childhood ear infection; LIHC cis rs9916302 0.851 rs11078907 chr17:37662954 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC cis rs10174077 0.874 rs11892439 chr2:152469858 T/A cg19508488 chr2:152266495 RIF1 0.5 7.15 0.36 5.24e-12 Squamous cell lung carcinoma; LIHC cis rs12477438 0.700 rs12467679 chr2:99654449 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.89 -0.54 1.56e-27 Chronic sinus infection; LIHC cis rs611744 0.608 rs612744 chr8:109245991 G/A cg18478394 chr8:109455254 TTC35 0.41 7.01 0.35 1.28e-11 Dupuytren's disease; LIHC trans rs6934970 1.000 rs12196496 chr6:113021779 T/A cg20627988 chr10:133946881 JAKMIP3 0.49 6.36 0.33 6.55e-10 Bipolar disorder (body mass index interaction); LIHC cis rs9640161 0.830 rs6722 chr7:150068933 T/C cg21361702 chr7:150065534 REPIN1 0.52 7.28 0.37 2.38e-12 Blood protein levels;Circulating chemerin levels; LIHC cis rs2066819 1.000 rs117683816 chr12:56638267 T/C cg26734620 chr12:56694298 CS 1.23 10.54 0.5 1.14e-22 Psoriasis vulgaris; LIHC cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg00166722 chr3:10149974 C3orf24 0.51 6.03 0.31 4.36e-9 Alzheimer's disease; LIHC trans rs704178 0.967 rs829079 chr12:21999108 A/C cg13945301 chr2:157190182 NR4A2 0.38 6.13 0.31 2.4e-9 Hippocampal sclerosis of aging; LIHC cis rs739401 0.611 rs494427 chr11:3048140 A/G cg20651018 chr11:3035856 CARS -0.34 -5.75 -0.3 2.03e-8 Longevity; LIHC cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg00656387 chr3:40428638 ENTPD3 -0.42 -6.86 -0.35 3.15e-11 Renal cell carcinoma; LIHC cis rs79149102 0.579 rs74023935 chr15:75359184 T/C cg09165964 chr15:75287851 SCAMP5 -0.6 -7.78 -0.39 8.66e-14 Lung cancer; LIHC trans rs11098499 0.863 rs2127823 chr4:120485670 G/T cg25214090 chr10:38739885 LOC399744 0.57 8.97 0.44 2.03e-17 Corneal astigmatism; LIHC cis rs7107174 1.000 rs2512541 chr11:77981747 A/T cg02023728 chr11:77925099 USP35 0.49 9.45 0.46 5.4e-19 Testicular germ cell tumor; LIHC cis rs7772486 0.686 rs857877 chr6:145976230 A/C cg13319975 chr6:146136371 FBXO30 0.37 6.02 0.31 4.42e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11758351 0.789 rs2069020 chr6:26205500 C/T cg16070018 chr6:26224392 HIST1H3E 0.6 7.43 0.37 8.88e-13 Gout;Renal underexcretion gout; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg23131131 chr22:24373011 LOC391322 -0.64 -9.32 -0.45 1.46e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7223966 0.961 rs17631394 chr17:61646000 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.55 -6.4 -0.33 5.19e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg25364880 chr3:44379878 C3orf23 0.47 6.68 0.34 9.7e-11 Depressive symptoms; LIHC cis rs4660306 0.677 rs6429566 chr1:45941852 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.64 -7.0 -0.35 1.36e-11 Homocysteine levels; LIHC cis rs4820539 1.000 rs5759595 chr22:23471624 G/A cg21100191 chr22:23484243 RTDR1 0.92 17.13 0.68 6.07e-48 Bone mineral density; LIHC cis rs7224314 1.000 rs8066725 chr17:65387326 G/A cg01507342 chr17:65387096 PITPNC1 -0.46 -5.9 -0.3 8.64e-9 Diisocyanate-induced asthma; LIHC cis rs9303401 1.000 rs6503877 chr17:56841948 C/T cg12560992 chr17:57184187 TRIM37 0.73 10.84 0.51 9.51e-24 Cognitive test performance; LIHC cis rs7677751 0.806 rs4864857 chr4:55089814 T/C cg17187183 chr4:55093834 PDGFRA 0.66 8.27 0.41 3.09e-15 Corneal astigmatism; LIHC cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg12379764 chr21:47803548 PCNT 0.63 8.95 0.44 2.25e-17 Testicular germ cell tumor; LIHC cis rs7615952 0.576 rs6780025 chr3:125815624 A/C cg05084668 chr3:125655381 ALG1L -0.38 -5.92 -0.3 7.91e-9 Blood pressure (smoking interaction); LIHC cis rs4407350 0.967 rs4501045 chr22:44922321 G/A cg26276947 chr22:44892394 LDOC1L 0.35 6.35 0.32 6.81e-10 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg21724239 chr8:58056113 NA 0.6 7.39 0.37 1.1e-12 Developmental language disorder (linguistic errors); LIHC cis rs9905704 0.647 rs10221208 chr17:57047885 T/C cg12560992 chr17:57184187 TRIM37 0.68 10.0 0.48 7.98e-21 Testicular germ cell tumor; LIHC cis rs1555399 0.901 rs7140470 chr14:67983559 T/C cg16224230 chr14:67978224 TMEM229B -0.24 -5.95 -0.31 6.51e-9 Parkinson's disease; LIHC cis rs17376456 0.825 rs10058331 chr5:93279115 T/G cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs561341 0.941 rs7215147 chr17:30266711 G/A cg13647721 chr17:30228624 UTP6 0.63 6.24 0.32 1.28e-9 Hip circumference adjusted for BMI; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg07897659 chr22:50316901 CRELD2 -0.49 -6.28 -0.32 1.01e-9 Alcohol dependence; LIHC cis rs2549003 1.000 rs9282761 chr5:131822224 T/C cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs2991971 0.967 rs12743512 chr1:45954033 A/G cg05343316 chr1:45956843 TESK2 0.45 6.6 0.34 1.58e-10 High light scatter reticulocyte count; LIHC cis rs9733 0.596 rs12072339 chr1:150686099 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs17401966 0.931 rs12408430 chr1:10323339 T/A cg15208524 chr1:10270712 KIF1B 0.4 6.02 0.31 4.4e-9 Hepatocellular carcinoma; LIHC cis rs7727544 0.684 rs274567 chr5:131714409 C/T cg07395648 chr5:131743802 NA 0.31 6.36 0.32 6.65e-10 Blood metabolite levels; LIHC cis rs5769765 0.526 rs5770722 chr22:50253220 G/C cg09182678 chr22:50328711 NA 0.47 6.0 0.31 5.14e-9 Schizophrenia; LIHC cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs75804782 0.521 rs56120037 chr2:239398464 G/A cg01134436 chr17:81009848 B3GNTL1 0.82 6.89 0.35 2.67e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs55665837 0.701 rs2007361 chr11:14662722 A/G cg00085434 chr11:14927489 NA 0.42 5.81 0.3 1.47e-8 Vitamin D levels; LIHC cis rs8067545 0.750 rs11869616 chr17:19992713 G/A cg13482628 chr17:19912719 NA 0.49 8.12 0.4 8.43e-15 Schizophrenia; LIHC trans rs8073060 0.586 rs225292 chr17:33926383 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -7.24 -0.36 3.05e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2732480 0.557 rs2732454 chr12:48719677 T/C cg21466736 chr12:48725269 NA -0.72 -11.01 -0.51 2.49e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs77106637 0.932 rs74439784 chr11:72649396 A/T cg03713592 chr11:72463424 ARAP1 0.77 6.64 0.34 1.25e-10 Type 2 diabetes; LIHC cis rs8141529 0.748 rs5762882 chr22:29290680 C/A cg15103426 chr22:29168792 CCDC117 0.58 9.41 0.45 7.61e-19 Lymphocyte counts; LIHC cis rs600806 0.854 rs10745353 chr1:109877506 A/G cg16275483 chr1:110013120 SYPL2 -0.5 -6.29 -0.32 9.82e-10 Intelligence (multi-trait analysis); LIHC cis rs7614311 0.731 rs1053338 chr3:63967900 A/G cg22134162 chr3:63841271 THOC7 -0.56 -6.18 -0.32 1.79e-9 Lung function (FVC);Lung function (FEV1); LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg25029360 chr8:141646502 EIF2C2 -0.48 -7.14 -0.36 5.71e-12 Body mass index; LIHC cis rs6973256 0.583 rs2042000 chr7:133322697 T/C cg10665199 chr7:133106180 EXOC4 0.34 5.77 0.3 1.76e-8 Intelligence (multi-trait analysis); LIHC trans rs61332075 0.500 rs55917008 chr2:239380244 C/A cg01134436 chr17:81009848 B3GNTL1 0.87 7.24 0.36 2.94e-12 Lung function (FEV1/FVC); LIHC cis rs9910055 0.573 rs113184718 chr17:42206543 A/T cg13607699 chr17:42295918 UBTF -0.44 -6.93 -0.35 2.08e-11 Total body bone mineral density; LIHC cis rs6546550 0.901 rs6546558 chr2:70145717 C/T cg02498382 chr2:70120550 SNRNP27 -0.42 -7.01 -0.35 1.28e-11 Prevalent atrial fibrillation; LIHC trans rs6598955 0.671 rs12089149 chr1:26638500 C/A cg07461501 chr17:79650226 HGS;ARL16 -0.74 -7.84 -0.39 5.66e-14 Obesity-related traits; LIHC trans rs13325613 0.915 rs71327040 chr3:46263208 G/T cg26337592 chr1:153642686 ILF2 0.68 6.2 0.32 1.66e-9 Monocyte count; LIHC cis rs919433 0.927 rs13032495 chr2:198189346 C/T cg03934865 chr2:198174659 NA -0.57 -9.07 -0.44 9.59e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg20302342 chr1:156215951 PAQR6 0.31 6.01 0.31 4.81e-9 Tonsillectomy; LIHC cis rs787274 0.543 rs4979177 chr9:115644266 G/A cg13803584 chr9:115635662 SNX30 -0.51 -6.05 -0.31 3.91e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs7714584 1.000 rs10053750 chr5:150270051 A/G cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg11494091 chr17:61959527 GH2 0.45 8.13 0.4 7.75e-15 Prudent dietary pattern; LIHC cis rs7264396 0.623 rs2590984 chr20:34597031 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.52 -9.1 -0.44 7.89e-18 Total cholesterol levels; LIHC cis rs9649465 0.967 rs3779261 chr7:123315174 A/G cg03229431 chr7:123269106 ASB15 -0.36 -7.57 -0.38 3.53e-13 Migraine; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.72 10.61 0.5 6.52e-23 Lymphocyte counts; LIHC cis rs6973256 0.569 rs9649595 chr7:133385921 G/C cg03336402 chr7:133662267 EXOC4 -0.38 -5.82 -0.3 1.35e-8 Intelligence (multi-trait analysis); LIHC cis rs7945718 0.967 rs11022496 chr11:12789561 G/A cg25843174 chr11:12811716 TEAD1 0.34 7.78 0.39 8.73e-14 Educational attainment (years of education); LIHC cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2635047 0.967 rs1119005 chr18:44725605 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.45 6.03 0.31 4.3e-9 Educational attainment; LIHC cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg08132940 chr7:1081526 C7orf50 -0.77 -6.47 -0.33 3.47e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12701220 0.744 rs2030958 chr7:1076010 G/T cg00990874 chr7:1149470 C7orf50 -0.66 -8.9 -0.43 3.25e-17 Bronchopulmonary dysplasia; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg12419862 chr22:24373484 LOC391322 -0.71 -11.0 -0.51 2.72e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9818758 0.607 rs61729488 chr3:49067904 T/C cg00383909 chr3:49044727 WDR6 1.1 7.88 0.39 4.53e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs921968 0.608 rs495855 chr2:219357858 A/G cg02985541 chr2:219472218 PLCD4 0.45 8.58 0.42 3.34e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs4423214 0.879 rs1630498 chr11:71150785 A/C cg05163923 chr11:71159392 DHCR7 -0.59 -8.12 -0.4 8.29e-15 Vitamin D levels; LIHC cis rs611744 0.967 rs630492 chr8:109215368 C/T cg21045802 chr8:109455806 TTC35 -0.49 -8.63 -0.42 2.38e-16 Dupuytren's disease; LIHC cis rs2153535 0.580 rs9406174 chr6:8516764 T/C cg23788917 chr6:8435910 SLC35B3 0.62 8.74 0.43 1.08e-16 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04479987 chr5:180649488 TRIM41 0.51 6.94 0.35 1.93e-11 Lung function (FEV1/FVC); LIHC cis rs1801251 0.778 rs709933 chr2:233733144 G/A cg08000102 chr2:233561755 GIGYF2 -0.71 -10.6 -0.5 6.94e-23 Coronary artery disease; LIHC cis rs870825 0.655 rs12502771 chr4:185635834 T/C cg04058563 chr4:185651563 MLF1IP 0.64 6.67 0.34 1.01e-10 Blood protein levels; LIHC cis rs2282802 0.685 rs7717576 chr5:139623591 G/A cg26211634 chr5:139558579 C5orf32 0.4 6.14 0.31 2.33e-9 Intelligence (multi-trait analysis); LIHC trans rs3780486 0.846 rs3780490 chr9:33129839 A/G cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC cis rs2257205 0.667 rs74961279 chr17:56904991 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -6.46 -0.33 3.5e-10 Pancreatic cancer; LIHC cis rs7772486 0.720 rs9403757 chr6:146261271 C/T cg23711669 chr6:146136114 FBXO30 -0.64 -11.17 -0.52 6.66e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs2760061 0.583 rs708113 chr1:228192753 T/A cg02753203 chr1:228287806 NA 0.61 10.43 0.49 2.63e-22 Diastolic blood pressure; LIHC cis rs2153535 0.580 rs7755284 chr6:8457479 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC trans rs11722228 0.549 rs73212853 chr4:10096230 C/T cg26043149 chr18:55253948 FECH 0.97 14.03 0.6 1.24e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs559928 0.597 rs11600667 chr11:63976183 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 7.43 0.37 8.73e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7927592 0.956 rs7126340 chr11:68257293 C/T cg01657329 chr11:68192670 LRP5 -0.46 -5.97 -0.31 6.03e-9 Total body bone mineral density; LIHC trans rs1005277 0.522 rs289643 chr10:37941494 T/G cg17830980 chr10:43048298 ZNF37B -0.41 -8.02 -0.4 1.73e-14 Extrinsic epigenetic age acceleration; LIHC cis rs9467773 0.967 rs7753565 chr6:26560012 A/G cg11502198 chr6:26597334 ABT1 0.44 6.47 0.33 3.46e-10 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.875 rs2814875 chr6:146305810 G/A cg13319975 chr6:146136371 FBXO30 -0.39 -6.39 -0.33 5.54e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10876993 0.806 rs1689598 chr12:58050500 G/C cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.79 -0.34 5.05e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs2425143 0.730 rs7263640 chr20:34314725 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs7940866 0.804 rs6590540 chr11:130805444 T/C cg12179176 chr11:130786555 SNX19 0.67 9.88 0.47 2.04e-20 Schizophrenia; LIHC trans rs66887589 0.627 rs3872807 chr4:120360251 T/A cg25214090 chr10:38739885 LOC399744 0.42 7.02 0.35 1.18e-11 Diastolic blood pressure; LIHC cis rs317689 0.819 rs317664 chr12:69704747 C/A cg20891283 chr12:69753455 YEATS4 0.58 8.74 0.43 1.09e-16 Response to diuretic therapy; LIHC cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC cis rs2230307 0.536 rs581097 chr1:100515920 C/T cg24955406 chr1:100503596 HIAT1 0.62 6.14 0.32 2.27e-9 Carotid intima media thickness; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg21881364 chr11:72438004 ARAP1 0.4 6.06 0.31 3.69e-9 Longevity; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg10840064 chr1:42800299 FOXJ3 0.45 6.07 0.31 3.33e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs9309711 0.961 rs11890651 chr2:3482796 T/G cg20315796 chr2:16690541 NA -0.26 -6.06 -0.31 3.55e-9 Neurofibrillary tangles; LIHC cis rs7903847 0.642 rs10786344 chr10:99165975 T/C cg08345082 chr10:99160200 RRP12 -0.4 -6.91 -0.35 2.39e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs860295 0.702 rs475550 chr1:155652081 A/T cg02153340 chr1:155202674 NA -0.35 -6.51 -0.33 2.71e-10 Body mass index; LIHC trans rs1814175 0.645 rs7103554 chr11:50027612 G/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs2576037 0.583 rs4890343 chr18:44540969 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.73 11.54 0.53 3.02e-26 Personality dimensions; LIHC cis rs4319547 0.656 rs28730465 chr12:122863864 A/C cg05707623 chr12:122985044 ZCCHC8 0.54 7.16 0.36 5.12e-12 Body mass index; LIHC cis rs6089584 0.927 rs2296083 chr20:60574216 C/T cg06108461 chr20:60628389 TAF4 -0.88 -13.75 -0.6 1.53e-34 Body mass index; LIHC trans rs2352908 0.729 rs2352911 chr14:49445212 A/G cg01449224 chr4:123073775 NA 0.46 6.04 0.31 4.1e-9 Social communication problems; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19015611 chr2:71126446 VAX2 0.38 6.03 0.31 4.17e-9 Lung function (FEV1/FVC); LIHC cis rs8064299 0.967 rs880827 chr17:72767435 C/T cg25054828 chr17:72772726 NAT9;TMEM104 -0.7 -11.93 -0.54 1.18e-27 Monocyte count; LIHC cis rs7258015 1.000 rs3176766 chr19:10449778 G/A cg13981319 chr19:10446556 ICAM3 0.42 6.61 0.34 1.5e-10 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs903552 0.736 rs2132196 chr15:102007089 A/G cg00659931 chr15:102010125 PCSK6 -0.5 -6.89 -0.35 2.76e-11 Diabetic kidney disease; LIHC cis rs7264396 0.623 rs78949029 chr20:34384964 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.51 -6.36 -0.33 6.6e-10 Total cholesterol levels; LIHC cis rs2839186 0.721 rs3788252 chr21:47661235 C/T cg05896524 chr21:47604654 C21orf56 0.5 7.75 0.39 1.03e-13 Testicular germ cell tumor; LIHC cis rs6062302 0.522 rs3787107 chr20:62230576 G/A cg09650180 chr20:62225654 GMEB2 -0.38 -5.97 -0.31 5.93e-9 Glioblastoma; LIHC cis rs34779708 0.702 rs4007272 chr10:35546859 T/G cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1348850 0.914 rs4893823 chr2:178285811 C/T cg02961200 chr2:178257176 LOC100130691;AGPS -0.85 -13.5 -0.59 1.35e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs8062405 0.723 rs4788079 chr16:28559363 C/A cg07382826 chr16:28625726 SULT1A1 0.48 7.48 0.37 6.43e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg12463550 chr7:65579703 CRCP 0.68 7.01 0.35 1.27e-11 Diabetic kidney disease; LIHC cis rs2731664 0.756 rs335433 chr5:176867207 T/C cg23176889 chr5:176863531 GRK6 -0.7 -12.51 -0.56 7.78e-30 Intelligence (multi-trait analysis); LIHC trans rs7917772 0.636 rs10786708 chr10:104526245 C/T cg07474051 chr12:120942642 COQ5 0.35 6.33 0.32 7.53e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1707322 1.000 rs12077974 chr1:46384141 G/A cg06784218 chr1:46089804 CCDC17 0.34 5.98 0.31 5.74e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9303401 0.659 rs12935851 chr17:56600244 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.94 12.87 0.57 3.56e-31 Cognitive test performance; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02048317 chr17:80004967 NA 0.42 6.54 0.33 2.25e-10 Pancreatic cancer; LIHC cis rs80282103 0.867 rs7099063 chr10:1078547 C/G cg18964960 chr10:1102726 WDR37 0.66 6.36 0.33 6.47e-10 Glomerular filtration rate (creatinine); LIHC cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.87 0.35 3.04e-11 Bipolar disorder; LIHC trans rs2072499 0.554 rs1052067 chr1:156206121 C/T cg02365086 chr1:27701171 FCN3 0.26 6.23 0.32 1.39e-9 Testicular germ cell tumor; LIHC cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.46 0.33 3.59e-10 Bipolar disorder; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg18867321 chr14:73493951 ZFYVE1 -0.54 -6.09 -0.31 2.97e-9 Lung function (FEV1); LIHC cis rs644799 0.526 rs693172 chr11:95636618 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.58 8.14 0.4 7.3e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs8027181 0.839 rs998021 chr15:72999825 T/C cg25996835 chr15:72978165 BBS4;HIGD2B 0.5 7.65 0.38 2.03e-13 Triglyceride levels; LIHC cis rs2839186 0.681 rs13047198 chr21:47701835 T/C cg12516959 chr21:47718080 NA -0.38 -5.89 -0.3 9.48e-9 Testicular germ cell tumor; LIHC cis rs7296418 0.961 rs4275659 chr12:123447928 C/T cg05973401 chr12:123451056 ABCB9 -0.53 -8.28 -0.41 2.78e-15 Platelet count; LIHC cis rs2404602 1.000 rs12594212 chr15:76802014 T/A cg03037974 chr15:76606532 NA 0.72 13.8 0.6 9.72e-35 Blood metabolite levels; LIHC cis rs6088580 0.634 rs4911419 chr20:32995873 G/A cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs116095464 0.558 rs7736600 chr5:231337 A/C cg22857025 chr5:266934 NA -1.48 -18.2 -0.7 3.22e-52 Breast cancer; LIHC cis rs1538970 0.847 rs781230 chr1:45880751 C/T cg24296786 chr1:45957014 TESK2 0.52 7.7 0.38 1.53e-13 Platelet count; LIHC cis rs9916302 0.904 rs4511574 chr17:37532916 A/G cg03013999 chr17:37608204 MED1 0.35 5.73 0.3 2.17e-8 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.763 rs7129248 chr11:68263276 A/T cg16797656 chr11:68205561 LRP5 0.51 9.07 0.44 9.37e-18 Total body bone mineral density; LIHC cis rs526821 0.595 rs624478 chr11:55340778 C/G cg04317927 chr11:55418816 OR4S2 0.47 9.0 0.44 1.6e-17 Pediatric bone mineral density (spine); LIHC trans rs35110281 0.774 rs1378080 chr21:45011315 T/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.35 0.32 6.86e-10 Mean corpuscular volume; LIHC cis rs9581857 0.579 rs3759434 chr13:27997700 A/C cg01674679 chr13:27998804 GTF3A -0.46 -6.86 -0.35 3.16e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs1499614 1.000 rs1638731 chr7:66144679 C/T cg18252515 chr7:66147081 NA -1.34 -18.69 -0.71 3.43e-54 Gout; LIHC cis rs921968 0.643 rs492400 chr2:219349752 C/T cg18887096 chr2:219472410 PLCD4 0.37 6.5 0.33 2.92e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9309473 0.748 rs2421552 chr2:73758803 C/T cg20560298 chr2:73613845 ALMS1 -0.55 -6.67 -0.34 1.06e-10 Metabolite levels; LIHC cis rs2932538 0.885 rs7516421 chr1:113089696 T/C cg22162597 chr1:113214053 CAPZA1 0.65 10.35 0.49 4.94e-22 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs910316 0.967 rs35446981 chr14:75637351 A/T cg11812906 chr14:75593930 NEK9 -0.74 -14.17 -0.61 3.62e-36 Height; LIHC cis rs523522 0.962 rs10744752 chr12:120900554 T/G cg27279351 chr12:120934652 DYNLL1 0.66 11.69 0.53 8.65e-27 High light scatter reticulocyte count; LIHC trans rs7618501 1.000 rs34451146 chr3:49813013 C/T cg21659725 chr3:3221576 CRBN 0.99 19.75 0.73 1.74e-58 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs2236762 chr17:41226675 A/T cg25072359 chr17:41440525 NA 0.41 6.74 0.34 6.89e-11 Menopause (age at onset); LIHC cis rs4555082 0.874 rs2735828 chr14:105710486 C/A cg13114125 chr14:105738426 BRF1 -0.71 -9.68 -0.46 9.94e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs1534166 0.647 rs13321680 chr3:133507119 G/T cg27366882 chr3:133540807 NA -0.43 -7.27 -0.37 2.43e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs950776 0.518 rs12906284 chr15:78825105 C/T cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs748404 0.631 rs12905772 chr15:43648444 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.86 0.43 4.31e-17 Lung cancer; LIHC cis rs9534288 0.797 rs2104516 chr13:46602123 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs910316 0.673 rs2012627 chr14:75443103 C/T cg08847533 chr14:75593920 NEK9 0.86 17.95 0.7 3.1e-51 Height; LIHC cis rs9303401 0.659 rs12600349 chr17:57054245 A/G cg25039879 chr17:56429692 SUPT4H1 -0.8 -9.03 -0.44 1.29e-17 Cognitive test performance; LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs13235972 chr7:65883605 C/T cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.53 7.75 0.39 1.08e-13 Lymphocyte counts; LIHC trans rs1005277 0.505 rs7069702 chr10:38247359 G/T cg23533926 chr12:111358616 MYL2 0.34 6.7 0.34 8.44e-11 Extrinsic epigenetic age acceleration; LIHC cis rs853679 0.517 rs3734573 chr6:28059437 T/C cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs68170813 0.559 rs4730231 chr7:106942039 G/C cg02696742 chr7:106810147 HBP1 -0.51 -5.94 -0.31 7.04e-9 Coronary artery disease; LIHC cis rs2071426 0.959 rs1592037 chr10:96792328 A/G cg09036531 chr10:96991505 NA 0.53 6.21 0.32 1.5e-9 Blood metabolite levels; LIHC cis rs611744 0.870 rs2212703 chr8:109198401 G/C cg21045802 chr8:109455806 TTC35 0.59 9.9 0.47 1.7e-20 Dupuytren's disease; LIHC cis rs9640161 0.830 rs11768108 chr7:150064150 C/T cg10018233 chr7:150070692 REPIN1 0.7 12.61 0.56 3.26e-30 Blood protein levels;Circulating chemerin levels; LIHC cis rs28735056 0.592 rs2277725 chr18:77694168 A/C cg20368463 chr18:77673604 PQLC1 -0.5 -9.16 -0.44 4.77e-18 Schizophrenia; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg02636461 chr16:69148474 HAS3 0.62 6.46 0.33 3.56e-10 Mean platelet volume; LIHC cis rs11711311 1.000 rs9854504 chr3:113532381 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.03 -0.36 1.15e-11 IgG glycosylation; LIHC cis rs1005277 0.579 rs1621040 chr10:38497232 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.28 -0.32 1.05e-9 Extrinsic epigenetic age acceleration; LIHC cis rs6570726 0.846 rs439035 chr6:145887990 G/C cg23711669 chr6:146136114 FBXO30 0.64 11.62 0.53 1.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs459571 0.959 rs410876 chr9:136893867 C/A cg13789015 chr9:136890014 NCRNA00094 0.45 8.29 0.41 2.54e-15 Platelet distribution width; LIHC cis rs796364 0.951 rs281769 chr2:200809709 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.27 0.41 2.94e-15 Schizophrenia; LIHC cis rs4819052 0.851 rs8127834 chr21:46696109 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 11.91 0.54 1.31e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7617773 0.963 rs12493256 chr3:48176747 C/T cg11946769 chr3:48343235 NME6 -0.53 -7.14 -0.36 5.77e-12 Coronary artery disease; LIHC cis rs9420 0.884 rs644883 chr11:57663522 C/G cg19752551 chr11:57585705 CTNND1 0.41 5.85 0.3 1.15e-8 Schizophrenia; LIHC cis rs4713118 0.911 rs2394000 chr6:27686991 A/G cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC trans rs10242455 0.571 rs11734 chr7:99229768 C/G cg09045935 chr12:6379348 NA -0.68 -6.03 -0.31 4.17e-9 Blood metabolite levels; LIHC cis rs4788570 0.615 rs6499531 chr16:71731485 T/C cg06353428 chr16:71660113 MARVELD3 1.32 13.45 0.59 2.06e-33 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg07308232 chr7:1071921 C7orf50 -0.55 -8.98 -0.44 1.89e-17 Longevity;Endometriosis; LIHC cis rs5758659 0.714 rs5751220 chr22:42516205 A/C cg19513890 chr22:42538836 CYP2D7P1 0.43 8.39 0.41 1.3e-15 Cognitive function; LIHC cis rs3749237 0.595 rs1464568 chr3:49458266 G/A cg02487422 chr3:49467188 NICN1 0.41 6.41 0.33 4.97e-10 Resting heart rate; LIHC cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg22963979 chr7:1858916 MAD1L1 -0.44 -7.14 -0.36 5.71e-12 Bipolar disorder and schizophrenia; LIHC cis rs2832191 0.740 rs6516890 chr21:30476812 T/A cg08807101 chr21:30365312 RNF160 0.64 10.2 0.48 1.61e-21 Dental caries; LIHC trans rs7618501 0.699 rs2777888 chr3:49898000 A/G cg21659725 chr3:3221576 CRBN 0.74 11.57 0.53 2.4e-26 Intelligence (multi-trait analysis); LIHC trans rs11989868 0.609 rs17320272 chr8:14541970 A/G cg02565878 chr1:111295745 NA -0.45 -6.06 -0.31 3.63e-9 Obesity-related traits; LIHC cis rs12477438 0.520 rs6542864 chr2:99725223 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.88 15.52 0.64 1.69e-41 Chronic sinus infection; LIHC cis rs7250872 0.606 rs1078229 chr19:1826383 A/C cg18850929 chr19:1828978 REXO1 0.39 6.34 0.32 7.27e-10 Bipolar disorder; LIHC cis rs769267 0.930 rs10419912 chr19:19597055 A/G cg03709012 chr19:19516395 GATAD2A -1.02 -18.43 -0.71 3.5e-53 Tonsillectomy; LIHC cis rs10744422 0.800 rs6489240 chr12:123275030 T/C cg18912006 chr12:123335444 HIP1R -0.54 -6.24 -0.32 1.27e-9 Schizophrenia; LIHC cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg09177884 chr7:1199841 ZFAND2A -0.44 -6.0 -0.31 4.95e-9 Longevity;Endometriosis; LIHC cis rs616402 0.527 rs10779737 chr1:10580275 C/G cg17425144 chr1:10567563 PEX14 0.61 12.78 0.57 7.77e-31 Breast size; LIHC trans rs72829446 0.530 rs7210292 chr17:7380305 G/T cg08566640 chr11:64091735 NA -0.69 -6.5 -0.33 2.77e-10 Androgen levels; LIHC cis rs7208859 0.623 rs9911997 chr17:29124648 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00004055 chr16:66586745 CKLF 0.48 6.48 0.33 3.29e-10 Pancreatic cancer; LIHC cis rs7520050 0.933 rs6656022 chr1:46394315 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.6e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11663156 1.000 rs67318347 chr18:50915178 A/G cg24270629 chr18:50823537 DCC -0.49 -6.64 -0.34 1.21e-10 Intelligence (multi-trait analysis); LIHC cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg20891558 chr2:74357851 NA 0.81 16.82 0.67 1.1e-46 Gestational age at birth (maternal effect); LIHC cis rs10911251 0.528 rs4652777 chr1:183091992 T/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Colorectal cancer; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs34779708 0.733 rs12777960 chr10:35541026 C/A cg03585969 chr10:35415529 CREM 0.76 11.02 0.51 2.18e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7487075 0.619 rs10748448 chr12:46803338 C/T cg23829395 chr12:46796953 NA 0.36 6.43 0.33 4.34e-10 Itch intensity from mosquito bite; LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg07677032 chr17:61819896 STRADA 0.43 6.28 0.32 1.02e-9 Prudent dietary pattern; LIHC cis rs2070433 0.851 rs1029231 chr21:47931653 A/G cg12379764 chr21:47803548 PCNT 0.6 8.79 0.43 7.23e-17 Lymphocyte counts; LIHC cis rs539514 0.690 rs2761398 chr13:76316933 C/A cg04757411 chr13:76259545 LMO7 -0.46 -8.13 -0.4 7.86e-15 Type 1 diabetes; LIHC trans rs4927850 1.000 rs6799572 chr3:195740408 C/T cg16724585 chr3:197361211 NA -0.46 -6.39 -0.33 5.35e-10 Pancreatic cancer; LIHC cis rs8014204 0.816 rs10083386 chr14:75347585 C/A cg08847533 chr14:75593920 NEK9 -0.36 -6.13 -0.31 2.39e-9 Caffeine consumption; LIHC cis rs1003719 0.667 rs6517404 chr21:38494918 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.76 12.09 0.55 2.83e-28 Eye color traits; LIHC trans rs8073060 0.821 rs11080355 chr17:33872694 T/A cg19694781 chr19:47549865 TMEM160 0.68 7.36 0.37 1.37e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs2000813 0.857 rs11082763 chr18:47100285 G/T cg01564661 chr14:105942636 CRIP2 0.34 6.12 0.31 2.64e-9 Coronary artery disease; LIHC cis rs7312933 0.558 rs11181422 chr12:42718552 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.02 -0.4 1.66e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6674176 0.628 rs3791119 chr1:44431362 C/G cg12908607 chr1:44402522 ARTN -0.5 -8.44 -0.41 9.44e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs113252371 1 rs113252371 chr16:30476517 C/T cg17640201 chr16:30407289 ZNF48 -0.63 -6.06 -0.31 3.58e-9 Number of common colds; LIHC cis rs2933343 0.729 rs1680786 chr3:128644840 T/C cg24203234 chr3:128598194 ACAD9 0.46 6.47 0.33 3.43e-10 IgG glycosylation; LIHC cis rs6089829 0.962 rs3899032 chr20:61658542 G/A cg08564027 chr20:61660810 NA 0.4 7.71 0.38 1.38e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs155076 0.711 rs9550724 chr13:21885030 G/T cg11317459 chr13:21872234 NA 1.29 14.02 0.6 1.4e-35 White matter hyperintensity burden; LIHC cis rs6138458 1.000 rs227629 chr20:24913551 G/T cg26195577 chr20:24973756 C20orf3 1.12 14.83 0.63 9.49e-39 Blood protein levels; LIHC cis rs1799949 0.965 rs799917 chr17:41244936 G/A cg05368731 chr17:41323189 NBR1 0.68 11.46 0.53 5.83e-26 Menopause (age at onset); LIHC cis rs2839186 0.500 rs13052701 chr21:47660045 A/T cg09417038 chr21:47716443 C21orf57 -0.66 -9.65 -0.46 1.19e-19 Testicular germ cell tumor; LIHC cis rs867186 0.614 rs75401510 chr20:33434423 C/G cg08999081 chr20:33150536 PIGU 0.63 5.88 0.3 9.63e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg11733071 chr1:886543 NOC2L -0.47 -6.06 -0.31 3.63e-9 Alcohol dependence; LIHC trans rs208520 0.690 rs9345764 chr6:66820597 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.86 -9.23 -0.45 2.89e-18 Exhaled nitric oxide output; LIHC cis rs9309473 0.948 rs10170849 chr2:73747932 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.9 -0.35 2.48e-11 Metabolite levels; LIHC trans rs60843830 1.000 rs60149603 chr2:285421 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.29 0.45 1.82e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25683012 chr12:57030113 BAZ2A 0.37 6.5 0.33 2.79e-10 Cognitive function; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23001456 chr17:2615074 KIAA0664 -0.45 -6.18 -0.32 1.85e-9 Systolic blood pressure; LIHC cis rs4237845 0.537 rs9645819 chr12:58270063 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.57 7.95 0.4 2.67e-14 Intelligence (multi-trait analysis); LIHC cis rs7659604 0.702 rs61217486 chr4:122693973 T/C cg20573242 chr4:122745356 CCNA2 0.49 7.23 0.36 3.24e-12 Type 2 diabetes; LIHC cis rs4555082 0.874 rs1882846 chr14:105717448 G/C cg06808227 chr14:105710500 BRF1 -0.54 -7.08 -0.36 8.23e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg10755058 chr3:40428713 ENTPD3 -0.4 -6.92 -0.35 2.2e-11 Renal cell carcinoma; LIHC cis rs7193541 1.000 rs7193541 chr16:74664743 C/T cg01733217 chr16:74700730 RFWD3 -0.53 -10.31 -0.49 7.21e-22 Multiple myeloma; LIHC cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg14393609 chr7:65229607 NA -0.43 -6.39 -0.33 5.36e-10 Aortic root size; LIHC cis rs7959452 0.640 rs4761154 chr12:69705362 A/G cg22834771 chr12:69754056 YEATS4 0.48 8.05 0.4 1.34e-14 Blood protein levels; LIHC cis rs988712 0.550 rs988748 chr11:27724745 C/G cg18117895 chr11:27722066 BDNF -0.5 -6.91 -0.35 2.37e-11 Obesity; LIHC cis rs12995491 0.933 rs12995212 chr2:88527184 C/T cg04511125 chr2:88470314 THNSL2 -0.41 -6.26 -0.32 1.13e-9 Response to metformin (IC50); LIHC cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg12292205 chr6:26970375 C6orf41 -0.42 -7.08 -0.36 8.14e-12 Schizophrenia; LIHC cis rs7635838 0.617 rs367745 chr3:11309274 T/C cg00170343 chr3:11313890 ATG7 0.61 10.35 0.49 5.15e-22 HDL cholesterol; LIHC cis rs778371 0.874 rs938575 chr2:233768788 G/A cg08000102 chr2:233561755 GIGYF2 -0.73 -8.77 -0.43 8.27e-17 Schizophrenia; LIHC cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg13409248 chr3:40428643 ENTPD3 0.41 6.62 0.34 1.39e-10 Renal cell carcinoma; LIHC cis rs1775715 0.870 rs7912121 chr10:32228995 T/G cg14930904 chr10:32216787 ARHGAP12 0.38 6.76 0.34 5.84e-11 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg27491609 chr17:62779607 LOC146880 0.43 6.24 0.32 1.31e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs644799 0.672 rs11021307 chr11:95501407 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.25 0.58 1.22e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12477438 0.765 rs28648058 chr2:99696417 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.34e-15 Chronic sinus infection; LIHC cis rs757081 0.637 rs586785 chr11:17208714 T/C cg15432903 chr11:17409602 KCNJ11 -0.43 -5.96 -0.31 6.23e-9 Systolic blood pressure; LIHC cis rs67460515 0.500 rs1868105 chr3:160645335 A/G cg03342759 chr3:160939853 NMD3 -0.51 -7.13 -0.36 5.99e-12 Parkinson's disease; LIHC cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg23758822 chr17:41437982 NA 0.95 17.65 0.69 4.96e-50 Menopause (age at onset); LIHC cis rs826838 0.967 rs11183622 chr12:38792849 T/C cg26384229 chr12:38710491 ALG10B 1.06 14.27 0.61 1.46e-36 Heart rate; LIHC cis rs28374715 0.532 rs28897479 chr15:41690851 T/G cg18705301 chr15:41695430 NDUFAF1 -1.26 -17.34 -0.68 8.8e-49 Ulcerative colitis; LIHC cis rs57590327 0.555 rs13072957 chr3:81776242 A/G cg07356753 chr3:81810745 GBE1 0.56 8.66 0.42 1.86e-16 Extraversion; LIHC cis rs12101261 0.580 rs3783949 chr14:81448382 A/C cg06600135 chr14:81408086 NA 0.4 7.4 0.37 1.06e-12 Graves' disease; LIHC cis rs7959452 0.605 rs12819406 chr12:69696400 G/T cg22834771 chr12:69754056 YEATS4 -0.48 -8.11 -0.4 9.46e-15 Blood protein levels; LIHC trans rs71435601 0.943 rs67332771 chr2:21312210 C/T cg01780092 chr15:83380063 AP3B2 0.61 6.14 0.32 2.25e-9 Cholesterol, total; LIHC cis rs7619427 1.000 rs7631201 chr3:44069531 A/C cg24966902 chr3:44043705 NA 0.56 7.76 0.39 9.6e-14 Schizophrenia; LIHC cis rs6504950 0.720 rs12602751 chr17:52994174 C/A cg10237252 chr17:52977213 TOM1L1 -0.36 -6.32 -0.32 8.02e-10 Breast cancer; LIHC cis rs11122272 0.766 rs2790870 chr1:231543823 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.26 0.45 2.39e-18 Hemoglobin concentration; LIHC cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Electroencephalogram traits; LIHC cis rs4819052 0.851 rs1056101 chr21:46678702 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.71 0.38 1.42e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1728785 0.901 rs1170438 chr16:68608256 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.3 0.32 8.99e-10 Ulcerative colitis; LIHC cis rs9902453 0.967 rs12602258 chr17:28317657 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.77 0.54 4.41e-27 Coffee consumption (cups per day); LIHC cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg22800045 chr5:56110881 MAP3K1 0.67 8.65 0.42 2.06e-16 Initial pursuit acceleration; LIHC trans rs208520 0.690 rs6932475 chr6:66863155 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.23 -0.41 3.97e-15 Exhaled nitric oxide output; LIHC cis rs13118159 0.801 rs1128427 chr4:1330759 T/C cg19318889 chr4:1322082 MAEA 0.45 6.95 0.35 1.91e-11 Longevity; LIHC cis rs7208859 0.623 rs11657777 chr17:29091785 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 8.11e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11190604 0.767 rs77838250 chr10:102180090 T/G cg07080220 chr10:102295463 HIF1AN 0.47 6.87 0.35 3.04e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs769267 0.930 rs10422819 chr19:19643028 C/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.4 5.84 0.3 1.2e-8 Tonsillectomy; LIHC cis rs7238033 0.663 rs11660575 chr18:43320438 A/G cg20610511 chr18:43302872 SLC14A1 0.37 6.23 0.32 1.37e-9 Bladder cancer; LIHC cis rs3806933 0.522 rs11241100 chr5:110460958 C/T cg04022379 chr5:110408740 TSLP 0.56 8.88 0.43 3.77e-17 Eosinophilic esophagitis; LIHC cis rs644799 0.932 rs480079 chr11:95643777 A/T cg03916912 chr11:95522834 CEP57;FAM76B -0.89 -16.5 -0.67 2.04e-45 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1023500 0.505 rs134888 chr22:42674281 C/T cg00645731 chr22:42541494 CYP2D7P1 0.35 6.12 0.31 2.61e-9 Schizophrenia; LIHC trans rs2496022 0.669 rs2451484 chr10:106596282 A/T cg23224828 chr19:52511591 ZNF615 0.57 6.33 0.32 7.87e-10 Depressive symptoms;Depressive symptoms (multi-trait analysis); LIHC cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs35146811 0.586 rs12705067 chr7:99594726 T/C cg19636519 chr7:99541626 NA 0.3 5.72 0.3 2.32e-8 Coronary artery disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08168689 chr14:76455272 C14orf179 0.44 6.56 0.33 1.93e-10 Longevity; LIHC cis rs10857712 0.528 rs2265638 chr10:135217175 A/G cg01444801 chr10:135216882 MTG1 -0.53 -8.65 -0.42 1.97e-16 Systemic lupus erythematosus; LIHC cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg04267008 chr7:1944627 MAD1L1 -0.57 -9.05 -0.44 1.12e-17 Schizophrenia; LIHC cis rs644799 1.000 rs544119 chr11:95538624 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2727020 0.729 rs2204366 chr11:49349367 A/C cg18944383 chr4:111397179 ENPEP -0.26 -6.35 -0.32 6.77e-10 Coronary artery disease; LIHC cis rs11608355 0.545 rs4766603 chr12:109892106 T/C cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07998070 chr1:206785660 LGTN 0.46 6.16 0.32 2.01e-9 Lung function (FEV1/FVC); LIHC trans rs1005277 0.522 rs7090858 chr10:38003670 A/C cg17830980 chr10:43048298 ZNF37B 0.42 8.07 0.4 1.23e-14 Extrinsic epigenetic age acceleration; LIHC cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.26 -0.45 2.28e-18 Bipolar disorder; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07192240 chr11:3829780 PGAP2 0.39 6.2 0.32 1.6e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs523522 0.962 rs655530 chr12:121022275 T/C cg27279351 chr12:120934652 DYNLL1 0.68 11.96 0.54 8.87e-28 High light scatter reticulocyte count; LIHC trans rs1814175 0.817 rs11040651 chr11:49938395 G/A cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13390975 chr5:34915890 BRIX1;RAD1 -0.46 -6.49 -0.33 2.98e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7772486 0.790 rs4075694 chr6:146251108 G/C cg23711669 chr6:146136114 FBXO30 -0.71 -12.43 -0.56 1.64e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg13409248 chr3:40428643 ENTPD3 -0.48 -8.37 -0.41 1.52e-15 Renal cell carcinoma; LIHC cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg07414643 chr4:187882934 NA 0.24 5.96 0.31 6.31e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4141404 0.923 rs2413046 chr22:31665909 C/A cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Paclitaxel-induced neuropathy; LIHC cis rs35883536 0.611 rs61070860 chr1:101097628 G/A cg14515779 chr1:101123966 NA -0.59 -11.3 -0.52 2.24e-25 Monocyte count; LIHC cis rs2242420 0.920 rs16825734 chr1:21956199 C/A cg18150885 chr1:21978612 RAP1GAP -0.48 -5.74 -0.3 2.13e-8 Hematological and biochemical traits; LIHC cis rs6732160 0.691 rs7599223 chr2:73427103 A/G cg24220031 chr2:73402428 NA -0.27 -5.87 -0.3 1.04e-8 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs11682621 chr2:27749669 G/A cg05484376 chr2:27715224 FNDC4 0.37 6.08 0.31 3.13e-9 Total body bone mineral density; LIHC cis rs12220238 0.822 rs2395087 chr10:76082637 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs713477 0.901 rs7146306 chr14:55905853 C/T cg13175173 chr14:55914753 NA -0.35 -8.13 -0.4 7.98e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs986417 1.000 rs1254292 chr14:60863636 T/C cg27398547 chr14:60952738 C14orf39 -0.78 -9.39 -0.45 8.39e-19 Gut microbiota (bacterial taxa); LIHC cis rs1816752 0.776 rs9511268 chr13:25018320 A/G cg22771759 chr13:24902376 NA 0.31 6.44 0.33 4.06e-10 Obesity-related traits; LIHC cis rs10751667 0.961 rs7395303 chr11:986221 T/A cg10932868 chr11:921992 NA 0.36 6.61 0.34 1.52e-10 Alzheimer's disease (late onset); LIHC cis rs3736485 0.966 rs4774595 chr15:51893161 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.25 -0.32 1.21e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6686842 0.601 rs213736 chr1:41623679 G/A cg08462924 chr1:41848221 NA 0.32 5.83 0.3 1.31e-8 Height; LIHC cis rs2404602 0.692 rs35170561 chr15:77130695 C/T cg23625390 chr15:77176239 SCAPER 0.36 5.87 0.3 1.04e-8 Blood metabolite levels; LIHC cis rs12220238 0.558 rs76330316 chr10:76002291 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.97 0.35 1.61e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1712517 0.771 rs11191672 chr10:105138961 C/T cg05636881 chr10:105038444 INA 0.48 7.47 0.37 6.6e-13 Migraine; LIHC cis rs9457247 0.765 rs9457251 chr6:167426707 T/C cg07741184 chr6:167504864 NA 0.32 7.4 0.37 1.06e-12 Crohn's disease; LIHC cis rs7584330 0.504 rs11890307 chr2:238434705 A/G cg08992911 chr2:238395768 MLPH 0.49 5.95 0.31 6.48e-9 Prostate cancer; LIHC trans rs1814175 0.791 rs11040472 chr11:49703116 C/T cg03929089 chr4:120376271 NA -0.92 -18.79 -0.71 1.28e-54 Height; LIHC cis rs7534824 0.543 rs17408457 chr1:101385693 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.41 0.37 9.75e-13 Refractive astigmatism; LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg14159672 chr1:205819179 PM20D1 0.86 12.47 0.56 1.11e-29 Menarche (age at onset); LIHC cis rs35110281 0.681 rs162343 chr21:44957072 A/G cg21573476 chr21:45109991 RRP1B -0.53 -9.64 -0.46 1.29e-19 Mean corpuscular volume; LIHC cis rs6754311 0.593 rs1438305 chr2:136502792 C/G cg07169764 chr2:136633963 MCM6 -0.68 -9.9 -0.47 1.81e-20 Mosquito bite size; LIHC cis rs8017423 0.967 rs7142513 chr14:90705182 T/C cg14092571 chr14:90743983 NA -0.37 -5.82 -0.3 1.37e-8 Mortality in heart failure; LIHC cis rs588177 0.919 rs2244625 chr11:64026144 G/A cg24431193 chr11:63883947 FLRT1;MACROD1 -0.46 -6.83 -0.35 3.83e-11 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs4555082 0.915 rs2816632 chr14:105741355 C/T cg13114125 chr14:105738426 BRF1 0.68 9.54 0.46 2.86e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs568617 0.903 rs601863 chr11:65646557 C/A cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.37 -0.33 5.93e-10 Crohn's disease; LIHC cis rs4759375 1.000 rs10773005 chr12:123790007 A/G cg00376283 chr12:123451042 ABCB9 -0.49 -6.25 -0.32 1.25e-9 HDL cholesterol; LIHC cis rs2153535 0.601 rs2327054 chr6:8443130 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.0 0.4 1.99e-14 Motion sickness; LIHC cis rs9303401 0.659 rs9303399 chr17:56672309 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 8.78 0.43 7.86e-17 Cognitive test performance; LIHC cis rs7618501 0.521 rs11709573 chr3:49956628 C/T cg24110177 chr3:50126178 RBM5 -0.55 -8.82 -0.43 5.8e-17 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs1534026 chr3:134284767 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7945718 0.935 rs4757059 chr11:12812356 G/A cg25843174 chr11:12811716 TEAD1 -0.37 -8.48 -0.42 7.03e-16 Educational attainment (years of education); LIHC cis rs60733400 0.817 rs4648657 chr1:2560735 A/G cg18854424 chr1:2615690 NA -0.33 -7.15 -0.36 5.32e-12 Multiple sclerosis; LIHC cis rs244731 0.959 rs9313752 chr5:176645435 G/T cg17509989 chr5:176798049 RGS14 -0.67 -6.49 -0.33 2.97e-10 Urate levels in lean individuals; LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg16132339 chr22:24313637 DDTL;DDT -0.65 -11.29 -0.52 2.49e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618915 0.781 rs12489732 chr3:52566820 C/A cg11645453 chr3:52864694 ITIH4 0.23 5.99 0.31 5.41e-9 Bipolar disorder; LIHC cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.13 -0.31 2.37e-9 Colorectal cancer; LIHC cis rs11190604 0.767 rs11190519 chr10:102175133 C/T cg07080220 chr10:102295463 HIF1AN 0.45 6.15 0.32 2.12e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg18252515 chr7:66147081 NA -1.24 -15.85 -0.65 7.92e-43 Diabetic kidney disease; LIHC cis rs3213545 0.659 rs2259690 chr12:121457914 T/G cg15155738 chr12:121454335 C12orf43 0.47 6.81 0.35 4.38e-11 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg20607798 chr8:58055168 NA 0.71 8.57 0.42 3.56e-16 Developmental language disorder (linguistic errors); LIHC cis rs433852 0.904 rs8102492 chr19:49140809 A/C cg06530960 chr19:49140787 SEC1;DBP 0.58 8.91 0.43 3.18e-17 Elevated serum carcinoembryonic antigen levels;Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.63 0.53 1.49e-26 Alzheimer's disease; LIHC cis rs7224737 1.000 rs739637 chr17:40280944 G/C cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs2404602 0.716 rs3866543 chr15:76629609 T/G cg03037974 chr15:76606532 NA 0.9 19.49 0.73 2.01e-57 Blood metabolite levels; LIHC cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg11645453 chr3:52864694 ITIH4 0.21 5.71 0.3 2.41e-8 Bipolar disorder; LIHC cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg24531977 chr5:56204891 C5orf35 -0.66 -9.52 -0.46 3.25e-19 Initial pursuit acceleration; LIHC cis rs2303759 0.709 rs2278405 chr19:49812403 A/C cg22307029 chr19:49891270 CCDC155 -0.55 -8.38 -0.41 1.35e-15 Multiple sclerosis; LIHC cis rs11190604 1.000 rs7084810 chr10:102297546 A/G cg07080220 chr10:102295463 HIF1AN 0.53 7.61 0.38 2.76e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6952808 0.825 rs34922657 chr7:1938655 C/T cg02951883 chr7:2050386 MAD1L1 -0.62 -9.29 -0.45 1.89e-18 Bipolar disorder and schizophrenia; LIHC cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.48 0.56 1.07e-29 Alzheimer's disease; LIHC cis rs10454142 0.731 rs11680719 chr2:48657843 G/A cg15846641 chr2:48541264 FOXN2 0.47 6.29 0.32 9.97e-10 Sex hormone-binding globulin levels; LIHC trans rs6598955 0.627 rs7550127 chr1:26592871 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.76 -8.53 -0.42 4.81e-16 Obesity-related traits; LIHC cis rs11583043 0.793 rs3903905 chr1:101420957 G/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.8 0.3 1.48e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs7615952 0.515 rs4441610 chr3:125681307 C/G cg07211511 chr3:129823064 LOC729375 -0.57 -7.21 -0.36 3.6e-12 Blood pressure (smoking interaction); LIHC cis rs7587476 0.601 rs6715570 chr2:215673440 T/C cg04530015 chr2:215796436 ABCA12 0.46 7.81 0.39 6.87e-14 Neuroblastoma; LIHC cis rs10751667 0.643 rs7396951 chr11:927355 G/A cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs6120849 0.754 rs752448 chr20:33592248 C/T cg24642439 chr20:33292090 TP53INP2 0.66 7.22 0.36 3.49e-12 Protein C levels; LIHC cis rs7100689 0.646 rs10736356 chr10:82148325 A/G cg00277334 chr10:82204260 NA -0.59 -7.6 -0.38 2.93e-13 Post bronchodilator FEV1; LIHC cis rs62458065 1.000 rs10231294 chr7:32465357 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.65 -7.37 -0.37 1.3e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs35146811 0.660 rs6465760 chr7:99591418 A/G cg19636519 chr7:99541626 NA -0.3 -5.86 -0.3 1.1e-8 Coronary artery disease; LIHC cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg06634786 chr22:41940651 POLR3H -0.81 -8.8 -0.43 7.01e-17 Vitiligo; LIHC cis rs875971 0.658 rs432667 chr7:65514633 A/G cg11764359 chr7:65958608 NA 0.85 14.27 0.61 1.37e-36 Aortic root size; LIHC cis rs826838 0.935 rs1486357 chr12:39073675 A/G cg13010199 chr12:38710504 ALG10B 0.55 6.8 0.34 4.81e-11 Heart rate; LIHC cis rs1552244 0.572 rs6785976 chr3:10168647 A/G cg00149659 chr3:10157352 C3orf10 0.92 8.77 0.43 8.28e-17 Alzheimer's disease; LIHC cis rs798554 0.797 rs1182183 chr7:2873136 C/T cg19346786 chr7:2764209 NA -0.43 -6.16 -0.32 2.02e-9 Height; LIHC cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg11764359 chr7:65958608 NA 0.58 6.04 0.31 3.97e-9 Diabetic kidney disease; LIHC cis rs10540 1.000 rs79808876 chr11:465763 C/A cg03352830 chr11:487213 PTDSS2 0.67 6.05 0.31 3.71e-9 Body mass index; LIHC trans rs9929218 0.906 rs9933844 chr16:68747001 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.64 -9.53 -0.46 2.96e-19 Colorectal cancer; LIHC cis rs172166 0.694 rs2791332 chr6:28108788 C/T cg25329415 chr6:28076851 NA 0.27 5.73 0.3 2.18e-8 Cardiac Troponin-T levels; LIHC cis rs11098499 0.863 rs6833334 chr4:120504227 C/T cg09307838 chr4:120376055 NA 0.75 11.88 0.54 1.71e-27 Corneal astigmatism; LIHC cis rs11031096 0.782 rs11031110 chr11:4162652 G/C cg18678763 chr11:4115507 RRM1 -0.58 -8.66 -0.42 1.92e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2072499 0.966 rs11587860 chr1:156156951 G/C cg25208724 chr1:156163844 SLC25A44 0.91 15.0 0.63 1.96e-39 Testicular germ cell tumor; LIHC cis rs4888262 0.545 rs7193959 chr16:74664969 T/A cg01733217 chr16:74700730 RFWD3 0.86 17.78 0.69 1.46e-50 Testicular germ cell tumor; LIHC cis rs7223966 1.000 rs8078862 chr17:61854068 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.87 0.35 2.98e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.15e-8 Crohn's disease;Inflammatory bowel disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15527401 chr19:59071099 UBE2M;LOC100131691 0.43 6.08 0.31 3.19e-9 Pancreatic cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13898548 chr5:176924827 PDLIM7 0.49 6.19 0.32 1.71e-9 Lung function (FEV1/FVC); LIHC cis rs1506636 0.512 rs1035015 chr7:123309842 G/C cg03229431 chr7:123269106 ASB15 0.49 5.72 0.3 2.37e-8 Plateletcrit;Platelet count; LIHC trans rs7615952 0.611 rs35321002 chr3:125612065 G/C cg07211511 chr3:129823064 LOC729375 -0.82 -8.86 -0.43 4.39e-17 Blood pressure (smoking interaction); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg20399842 chr2:21346738 NA 0.33 6.09 0.31 3.08e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg06108461 chr20:60628389 TAF4 -1.02 -17.6 -0.69 7.85e-50 Body mass index; LIHC cis rs10504229 1.000 rs66479724 chr8:58188309 T/G cg21724239 chr8:58056113 NA 0.47 6.27 0.32 1.09e-9 Developmental language disorder (linguistic errors); LIHC cis rs875971 1.000 rs778694 chr7:65871558 A/G cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs7503807 1.000 rs12936076 chr17:78601195 C/T cg09596252 chr17:78655493 RPTOR 0.4 7.12 0.36 6.22e-12 Obesity; LIHC cis rs2204008 0.782 rs117824012 chr12:38215517 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC trans rs911555 0.755 rs7148567 chr14:103882234 C/T cg17675199 chr6:35436792 RPL10A 0.38 7.83 0.39 6.17e-14 Intelligence (multi-trait analysis); LIHC trans rs4650994 1.000 rs10798615 chr1:178513895 T/G cg05059571 chr16:84539110 KIAA1609 -0.39 -6.53 -0.33 2.41e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs3736594 0.959 rs6547796 chr2:27975394 T/C cg27432699 chr2:27873401 GPN1 -0.43 -6.7 -0.34 8.46e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs943466 1.000 rs61394483 chr6:33751945 G/A cg25922239 chr6:33757077 LEMD2 -0.47 -5.78 -0.3 1.66e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg11890956 chr21:40555474 PSMG1 -0.5 -8.33 -0.41 2e-15 Menarche (age at onset); LIHC cis rs35110281 0.840 rs2838331 chr21:45026728 A/G cg21573476 chr21:45109991 RRP1B 0.58 10.89 0.51 6.3e-24 Mean corpuscular volume; LIHC cis rs8060686 0.623 rs74024145 chr16:68153382 G/C cg05110241 chr16:68378359 PRMT7 -0.5 -5.95 -0.31 6.56e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs875971 0.862 rs778734 chr7:65814849 C/G cg18876405 chr7:65276391 NA 0.35 6.36 0.33 6.34e-10 Aortic root size; LIHC cis rs4237845 0.837 rs7954591 chr12:58299037 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.43 6.04 0.31 3.94e-9 Intelligence (multi-trait analysis); LIHC cis rs10870270 0.956 rs7904594 chr10:133734671 C/T cg17892150 chr10:133769511 PPP2R2D -0.69 -13.16 -0.58 2.7e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1707322 0.717 rs1972410 chr1:46080947 G/T cg03146154 chr1:46216737 IPP 0.56 9.33 0.45 1.42e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17849194 chr4:71553882 UTP3 -0.45 -6.34 -0.32 7.34e-10 Pancreatic cancer; LIHC cis rs875971 1.000 rs778706 chr7:65860424 A/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs1707322 1.000 rs4524994 chr1:46370263 A/G cg03146154 chr1:46216737 IPP 0.47 7.51 0.38 5.08e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg02290350 chr8:58132656 NA 0.5 10.78 0.5 1.58e-23 Developmental language disorder (linguistic errors); LIHC cis rs3741798 1.000 rs61922027 chr12:12486444 C/T cg08615371 chr12:12503544 MANSC1 0.98 7.84 0.39 5.9e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs992157 0.767 rs2382822 chr2:219173327 T/C cg00012203 chr2:219082015 ARPC2 -0.8 -13.03 -0.58 8.36e-32 Colorectal cancer; LIHC cis rs12079745 0.793 rs12561922 chr1:169265794 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -7.09 -0.36 7.5e-12 QT interval; LIHC cis rs2932538 0.961 rs2932534 chr1:113200797 A/G cg22162597 chr1:113214053 CAPZA1 0.71 11.08 0.51 1.35e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7843479 0.601 rs9969551 chr8:21860007 T/C cg17168535 chr8:21777572 XPO7 0.57 10.01 0.48 7.37e-21 Mean corpuscular volume; LIHC cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg11764359 chr7:65958608 NA 0.57 5.82 0.3 1.39e-8 Diabetic kidney disease; LIHC cis rs3106136 0.843 rs6840479 chr4:95275842 A/G cg11021082 chr4:95130006 SMARCAD1 0.41 6.97 0.35 1.67e-11 Capecitabine sensitivity; LIHC cis rs7208859 0.673 rs450585 chr17:28951039 G/A cg14067834 chr17:29058358 SUZ12P 0.61 6.32 0.32 8.1e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs8017423 1.000 rs11622075 chr14:90669894 G/T cg04374321 chr14:90722782 PSMC1 0.71 13.43 0.59 2.6e-33 Mortality in heart failure; LIHC cis rs79149102 0.579 rs6495146 chr15:75367630 A/T cg16226627 chr15:75307476 SCAMP5 0.49 8.67 0.42 1.8e-16 Lung cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08536481 chr12:123459152 ABCB9;OGFOD2 -0.44 -6.28 -0.32 1e-9 Systolic blood pressure; LIHC cis rs3617 0.559 rs11915546 chr3:52866845 A/C cg11645453 chr3:52864694 ITIH4 -0.22 -5.95 -0.31 6.65e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs6426558 0.537 rs2670462 chr1:227432923 C/G cg10327440 chr1:227177885 CDC42BPA -0.42 -6.7 -0.34 8.43e-11 Neutrophil percentage of white cells; LIHC cis rs1577917 0.518 rs6454482 chr6:86418188 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.33 6.06 0.31 3.52e-9 Response to antipsychotic treatment; LIHC cis rs7772486 0.754 rs6937661 chr6:146113299 T/C cg13319975 chr6:146136371 FBXO30 0.39 6.34 0.32 7.29e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg05665937 chr4:1216051 CTBP1 0.44 5.81 0.3 1.44e-8 Obesity-related traits; LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg18279126 chr7:2041391 MAD1L1 0.39 6.51 0.33 2.74e-10 Bipolar disorder and schizophrenia; LIHC cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.93 -10.22 -0.48 1.44e-21 Platelet count; LIHC cis rs12464559 0.522 rs1916301 chr2:152640498 G/A cg01189475 chr2:152685088 ARL5A 0.66 8.24 0.41 3.62e-15 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs12579753 0.879 rs11115009 chr12:82165409 G/T cg07988820 chr12:82153109 PPFIA2 0.5 6.13 0.31 2.37e-9 Resting heart rate; LIHC cis rs6076065 0.775 rs6083114 chr20:23379528 G/T cg11657817 chr20:23433608 CST11 0.31 6.69 0.34 9.31e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs7917772 0.503 rs7904955 chr10:104367092 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.73 0.57 1.18e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17152411 1.000 rs1065301 chr10:126616038 A/G cg07906193 chr10:126599966 NA 0.47 7.33 0.37 1.66e-12 Height; LIHC cis rs40363 0.645 rs250630 chr16:3524242 C/T cg00484396 chr16:3507460 NAT15 0.44 7.73 0.39 1.18e-13 Tuberculosis; LIHC cis rs7618501 0.603 rs72942333 chr3:49986118 T/C cg24110177 chr3:50126178 RBM5 -0.48 -7.78 -0.39 8.7e-14 Intelligence (multi-trait analysis); LIHC cis rs911119 0.837 rs2208289 chr20:23579526 A/G cg16589663 chr20:23618590 CST3 -0.65 -7.06 -0.36 9.21e-12 Chronic kidney disease; LIHC cis rs1878931 0.580 rs4578649 chr16:3407258 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.83 -14.16 -0.61 3.9e-36 Body mass index (adult); LIHC cis rs4517514 0.509 rs2156434 chr11:89896417 A/G cg05041596 chr11:89867385 NAALAD2 0.42 6.71 0.34 7.96e-11 Trans fatty acid levels; LIHC cis rs4684776 0.867 rs1470612 chr3:11336966 C/T cg00170343 chr3:11313890 ATG7 -0.49 -6.87 -0.35 3.06e-11 Small vessel stroke; LIHC cis rs3106136 0.678 rs6857185 chr4:95296089 C/T cg11021082 chr4:95130006 SMARCAD1 0.35 6.06 0.31 3.64e-9 Capecitabine sensitivity; LIHC cis rs208520 1.000 rs208523 chr6:66954195 G/C cg07460842 chr6:66804631 NA -0.65 -7.0 -0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs7116495 0.609 rs1548348 chr11:71750917 A/G cg10381502 chr11:71823885 C11orf51 -1.08 -9.2 -0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs6952808 0.782 rs4236271 chr7:1881369 C/T cg10360139 chr7:1886902 MAD1L1 -0.38 -6.0 -0.31 5.12e-9 Bipolar disorder and schizophrenia; LIHC cis rs1371867 0.846 rs1660346 chr8:101312497 A/G cg06636551 chr8:101224915 SPAG1 -0.49 -8.91 -0.43 3e-17 Atrioventricular conduction; LIHC cis rs9318086 0.712 rs9318100 chr13:24442482 A/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.58 -11.56 -0.53 2.66e-26 Myopia (pathological); LIHC trans rs10411161 1.000 rs10414104 chr19:52368132 G/A cg22319618 chr22:45562946 NUP50 -0.51 -6.83 -0.35 4.01e-11 Breast cancer; LIHC cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg03517284 chr6:25882590 NA 0.87 12.06 0.55 3.78e-28 Blood metabolite levels; LIHC cis rs28595532 0.702 rs72670252 chr4:119337546 A/C cg21605333 chr4:119757512 SEC24D 1.08 8.7 0.43 1.4e-16 Cannabis dependence symptom count; LIHC cis rs11758351 0.660 rs75156165 chr6:26235699 C/A cg03854865 chr6:26224070 HIST1H3E 0.59 6.49 0.33 3.04e-10 Gout;Renal underexcretion gout; LIHC cis rs6952808 0.595 rs3800916 chr7:2166072 C/T cg20295408 chr7:1910781 MAD1L1 -0.4 -5.81 -0.3 1.41e-8 Bipolar disorder and schizophrenia; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg14004847 chr7:1930337 MAD1L1 0.57 8.82 0.43 5.76e-17 Bipolar disorder and schizophrenia; LIHC cis rs992157 0.560 rs4674274 chr2:219089131 A/T cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.22 -0.55 9.39e-29 Colorectal cancer; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg01238044 chr22:24384105 GSTT1 -0.41 -5.79 -0.3 1.56e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10876993 0.928 rs2640629 chr12:58065448 C/T cg18357645 chr12:58087776 OS9 0.53 8.73 0.43 1.16e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs4474465 0.736 rs4945291 chr11:78254413 C/T cg27205649 chr11:78285834 NARS2 0.39 5.95 0.31 6.52e-9 Alzheimer's disease (survival time); LIHC cis rs6714710 0.603 rs2305143 chr2:98413781 C/T cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg11062466 chr8:58055876 NA 0.49 7.3 0.37 2.09e-12 Developmental language disorder (linguistic errors); LIHC cis rs9467773 1.000 rs9467774 chr6:26505036 C/A cg09904177 chr6:26538194 HMGN4 0.66 13.85 0.6 6.03e-35 Intelligence (multi-trait analysis); LIHC cis rs17401966 1.000 rs11121533 chr1:10292888 G/C cg15208524 chr1:10270712 KIF1B 0.44 6.38 0.33 5.61e-10 Hepatocellular carcinoma; LIHC trans rs6580110 0.793 rs9324792 chr5:154078564 A/G cg02272667 chr7:1922866 MAD1L1 0.27 6.07 0.31 3.43e-9 Facial morphology (factor 9, facial height related to vertical position of nasion); LIHC cis rs2180341 0.814 rs6569488 chr6:127726256 C/T cg24812749 chr6:127587940 RNF146 0.8 12.66 0.56 2.11e-30 Breast cancer; LIHC cis rs523522 0.962 rs7136951 chr12:120941927 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.98 0.54 7.42e-28 High light scatter reticulocyte count; LIHC cis rs10865541 0.902 rs6739163 chr2:3419011 G/A cg11642891 chr2:3452563 TTC15 -0.45 -7.2 -0.36 3.8e-12 Obesity-related traits; LIHC cis rs986417 0.688 rs1950317 chr14:61022789 T/G cg27398547 chr14:60952738 C14orf39 0.6 7.42 0.37 9.36e-13 Gut microbiota (bacterial taxa); LIHC cis rs8072100 1.000 rs11650372 chr17:45721795 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.38 -6.06 -0.31 3.57e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7772486 0.654 rs1011597 chr6:146075672 A/C cg05347473 chr6:146136440 FBXO30 -0.35 -5.72 -0.3 2.34e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2076346 1.000 rs2076346 chr1:24083649 A/G cg15997130 chr1:24165203 NA 0.34 5.89 0.3 9.27e-9 Inflammatory skin disease; LIHC cis rs1395 0.744 rs1122227 chr2:27544285 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -6.05 -0.31 3.72e-9 Blood metabolite levels; LIHC cis rs919433 0.680 rs788018 chr2:198265526 A/G cg10820045 chr2:198174542 NA 0.56 9.0 0.44 1.6e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6674176 0.628 rs2240447 chr1:44415415 C/T cg12908607 chr1:44402522 ARTN -0.49 -8.36 -0.41 1.57e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7208859 0.673 rs216420 chr17:28938508 C/T cg14067834 chr17:29058358 SUZ12P 0.6 6.35 0.32 6.72e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9910055 0.573 rs113184718 chr17:42206543 A/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.79 -11.95 -0.54 9.9e-28 Total body bone mineral density; LIHC cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg21724239 chr8:58056113 NA 0.56 6.19 0.32 1.71e-9 Developmental language disorder (linguistic errors); LIHC cis rs700651 0.789 rs10184395 chr2:198894285 G/A cg10820045 chr2:198174542 NA 0.43 6.5 0.33 2.92e-10 Intracranial aneurysm; LIHC cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC cis rs2228479 0.717 rs9282682 chr16:89805794 A/G cg06558623 chr16:89946397 TCF25 0.82 11.12 0.52 1.01e-24 Skin colour saturation; LIHC cis rs1152591 1.000 rs1152591 chr14:64680848 A/G cg23250157 chr14:64679961 SYNE2 0.48 6.96 0.35 1.8e-11 Atrial fibrillation; LIHC cis rs7914558 1.000 rs10509757 chr10:104752960 C/T cg15744005 chr10:104629667 AS3MT -0.37 -8.42 -0.41 1.04e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs17376456 0.877 rs10057605 chr5:93443950 T/G cg25358565 chr5:93447407 FAM172A 1.14 10.33 0.49 6.1e-22 Diabetic retinopathy; LIHC cis rs6831352 0.918 rs34805407 chr4:100050786 C/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs6089584 0.566 rs2146852 chr20:60616492 T/G cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs908922 0.676 rs4845780 chr1:152488846 T/G cg20991723 chr1:152506922 NA 0.59 10.51 0.49 1.41e-22 Hair morphology; LIHC cis rs6500602 0.727 rs4238849 chr16:4538114 G/A cg08645402 chr16:4508243 NA 0.45 8.6 0.42 3e-16 Schizophrenia; LIHC cis rs12142240 0.698 rs41294458 chr1:46810304 T/C cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs11098499 0.820 rs13128602 chr4:120459366 C/T cg09307838 chr4:120376055 NA -0.76 -11.52 -0.53 3.54e-26 Corneal astigmatism; LIHC cis rs763121 0.853 rs5750671 chr22:39094619 A/C cg14440974 chr22:39074834 NA -0.37 -6.25 -0.32 1.21e-9 Menopause (age at onset); LIHC cis rs7107174 1.000 rs4945261 chr11:77990260 A/G cg02023728 chr11:77925099 USP35 -0.49 -9.29 -0.45 1.84e-18 Testicular germ cell tumor; LIHC cis rs3768617 0.510 rs10752895 chr1:183068505 C/G ch.1.3577855R chr1:183094577 LAMC1 0.63 10.94 0.51 4.28e-24 Fuchs's corneal dystrophy; LIHC cis rs950169 0.840 rs72748702 chr15:84915246 A/G cg12863693 chr15:85201151 NMB 0.41 5.93 0.31 7.37e-9 Schizophrenia; LIHC cis rs4332037 0.722 rs28705934 chr7:1916116 T/A cg23422044 chr7:1970798 MAD1L1 -0.69 -10.6 -0.5 6.89e-23 Bipolar disorder; LIHC cis rs6089829 0.962 rs9680064 chr20:61666168 G/A cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs7086627 0.515 rs10887900 chr10:82210265 A/G cg00277334 chr10:82204260 NA -0.78 -12.55 -0.56 5.47e-30 Post bronchodilator FEV1; LIHC trans rs1814175 0.587 rs847628 chr11:49927064 A/T cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs13161895 1.000 rs6873781 chr5:179436734 A/C cg06664874 chr5:179499304 RNF130 -0.58 -7.13 -0.36 5.93e-12 LDL cholesterol; LIHC cis rs7586673 0.857 rs16845580 chr2:161920884 T/C cg16506815 chr2:162101123 NA 0.47 7.74 0.39 1.17e-13 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20859525 chr6:80714300 TTK 0.5 7.7 0.38 1.5e-13 Cognitive function; LIHC cis rs9303401 0.614 rs62084384 chr17:57126842 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.02 0.58 9.58e-32 Cognitive test performance; LIHC cis rs7903847 0.619 rs76094900 chr10:99158164 G/A cg06359132 chr10:99160096 RRP12 -0.42 -6.43 -0.33 4.29e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs7246657 0.943 rs10422074 chr19:37894236 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC trans rs526821 0.595 rs532278 chr11:55344983 A/G cg03929089 chr4:120376271 NA -0.45 -6.85 -0.35 3.36e-11 Pediatric bone mineral density (spine); LIHC trans rs2243480 1.000 rs316307 chr7:65570171 C/T cg10756647 chr7:56101905 PSPH 1.07 13.42 0.59 2.9e-33 Diabetic kidney disease; LIHC cis rs6435862 0.517 rs6757091 chr2:215672793 G/C cg04004882 chr2:215674386 BARD1 -0.58 -8.74 -0.43 1.06e-16 Neuroblastoma (high-risk); LIHC cis rs2439831 1.000 rs2467740 chr15:43746792 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.67 0.59 3.13e-34 Lung cancer in ever smokers; LIHC cis rs4407350 0.870 rs1894461 chr22:44911287 C/T cg26276947 chr22:44892394 LDOC1L 0.34 6.56 0.33 1.99e-10 Intelligence (multi-trait analysis); LIHC cis rs12586317 0.547 rs4982234 chr14:35460106 T/A cg05294307 chr14:35346193 BAZ1A -0.5 -7.43 -0.37 8.87e-13 Psoriasis; LIHC cis rs12586317 0.547 rs114371385 chr14:35503724 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.38 0.59 4.02e-33 Psoriasis; LIHC trans rs4566357 0.615 rs12474622 chr2:227912793 A/G cg16088116 chr21:44841560 SIK1 -0.4 -6.23 -0.32 1.4e-9 Coronary artery disease; LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs2838855 chr21:46680566 C/G cg11663144 chr21:46675770 NA 0.32 6.06 0.31 3.56e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7095944 0.582 rs2303611 chr10:126517989 G/A cg20435097 chr10:126320824 FAM53B 0.35 5.93 0.31 7.57e-9 Asthma; LIHC cis rs4132509 1.000 rs73128287 chr1:243952150 T/G cg21452805 chr1:244014465 NA 0.42 5.72 0.3 2.35e-8 RR interval (heart rate); LIHC cis rs3806843 1.000 rs6898939 chr5:140169355 C/A cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg23172400 chr8:95962367 TP53INP1 -0.37 -8.23 -0.41 3.98e-15 Type 2 diabetes; LIHC cis rs1008375 0.898 rs7670500 chr4:17586957 A/G cg16339924 chr4:17578868 LAP3 0.45 6.24 0.32 1.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs561341 0.941 rs8066558 chr17:30272879 G/T cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 7.74e-24 Hip circumference adjusted for BMI; LIHC cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg13126279 chr21:47581558 C21orf56 -0.42 -6.51 -0.33 2.69e-10 Testicular germ cell tumor; LIHC cis rs2834188 1.000 rs2834187 chr21:34687410 A/G cg04842828 chr21:34696676 IFNAR1 0.45 6.0 0.31 5.04e-9 Narcolepsy; LIHC cis rs3020736 0.500 rs2413669 chr22:42507748 A/C cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.2 -0.32 1.67e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7618501 0.633 rs13060128 chr3:50025028 A/G cg24110177 chr3:50126178 RBM5 -0.47 -7.68 -0.38 1.64e-13 Intelligence (multi-trait analysis); LIHC cis rs11711311 0.826 rs13077644 chr3:113467777 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.26 -0.37 2.64e-12 IgG glycosylation; LIHC cis rs240764 0.658 rs11155635 chr6:101199367 C/T cg09795085 chr6:101329169 ASCC3 -0.45 -6.68 -0.34 9.69e-11 Neuroticism; LIHC cis rs7914558 0.966 rs3902934 chr10:104746649 A/G cg15744005 chr10:104629667 AS3MT -0.37 -8.38 -0.41 1.37e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2832077 0.527 rs2738953 chr21:30238363 G/C cg24692254 chr21:30365293 RNF160 0.44 6.78 0.34 5.33e-11 Cognitive test performance; LIHC cis rs7959452 0.557 rs7980883 chr12:69778914 C/T cg14784868 chr12:69753453 YEATS4 0.94 20.44 0.74 3.16e-61 Blood protein levels; LIHC cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg01448562 chr3:133502909 NA -0.42 -6.66 -0.34 1.1e-10 Iron status biomarkers; LIHC cis rs9733 0.596 rs6681990 chr1:150695929 A/G cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs7903847 0.620 rs10882904 chr10:99115683 A/G cg06359132 chr10:99160096 RRP12 -0.41 -6.12 -0.31 2.49e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs17345786 0.906 rs72944107 chr3:101197190 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.57 7.11 0.36 6.63e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs7534824 0.625 rs61780281 chr1:101324152 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 6.39 0.33 5.28e-10 Refractive astigmatism; LIHC cis rs62244186 0.659 rs9311358 chr3:44538748 C/G cg25364880 chr3:44379878 C3orf23 0.58 8.14 0.4 7.5e-15 Depressive symptoms; LIHC trans rs12960119 0.536 rs7342985 chr18:23722582 A/G cg05333146 chr16:67183725 B3GNT9 0.64 6.06 0.31 3.57e-9 Rhegmatogenous retinal detachment; LIHC cis rs644799 1.000 rs473155 chr11:95596873 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 16.25 0.66 2.16e-44 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs17106184 1.000 rs72904725 chr1:51334488 C/T cg07174182 chr1:51127561 FAF1 -0.62 -6.55 -0.33 2.17e-10 Type 2 diabetes; LIHC trans rs12620999 0.941 rs58678188 chr2:237971036 C/A cg15676719 chr1:167598521 RCSD1 0.34 6.13 0.31 2.36e-9 Systemic lupus erythematosus; LIHC cis rs11148252 0.875 rs9526913 chr13:52975837 T/C cg00495681 chr13:53174319 NA 0.39 6.51 0.33 2.75e-10 Lewy body disease; LIHC cis rs9560113 0.550 rs1163632 chr13:112231530 T/C cg10483660 chr13:112241077 NA -0.24 -6.4 -0.33 5.26e-10 Menarche (age at onset); LIHC cis rs6964587 0.967 rs58673519 chr7:91823887 T/G cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.2e-56 Breast cancer; LIHC cis rs67311347 0.866 rs56331709 chr3:40356558 A/C cg13409248 chr3:40428643 ENTPD3 0.38 5.82 0.3 1.35e-8 Renal cell carcinoma; LIHC cis rs7131987 0.868 rs11050151 chr12:29403008 T/A cg14222432 chr12:29376421 FAR2 0.37 7.17 0.36 4.76e-12 QT interval; LIHC cis rs66573146 0.572 rs68169399 chr4:6952491 T/A cg15105060 chr4:7024189 TBC1D14 -0.68 -6.1 -0.31 2.88e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs55665837 1.000 rs55665837 chr11:14495049 C/T cg19336497 chr11:14380999 RRAS2 -0.45 -8.33 -0.41 1.95e-15 Vitamin D levels; LIHC cis rs1008375 0.966 rs2286773 chr4:17616214 C/A cg04450456 chr4:17643702 FAM184B 0.35 5.81 0.3 1.45e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9649213 0.593 rs6944262 chr7:97985415 T/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.75 -0.3 2.03e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg17971929 chr21:40555470 PSMG1 0.86 10.31 0.49 7.16e-22 Cognitive function; LIHC cis rs950169 1.000 rs12903820 chr15:84723820 A/G cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs9649213 0.537 rs6971825 chr7:97979548 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs9911578 1.000 rs9915935 chr17:56843048 A/G cg12560992 chr17:57184187 TRIM37 0.95 16.88 0.67 6.01e-47 Intelligence (multi-trait analysis); LIHC cis rs2952156 0.883 rs907088 chr17:37833567 G/C cg00129232 chr17:37814104 STARD3 -0.53 -10.19 -0.48 1.76e-21 Asthma; LIHC cis rs7607369 0.626 rs4672892 chr2:219278630 A/G cg02176678 chr2:219576539 TTLL4 -0.51 -6.9 -0.35 2.51e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs360798 0.512 rs34104251 chr2:62995183 A/G cg17519650 chr2:63277830 OTX1 -0.43 -6.82 -0.35 4.15e-11 Coronary artery disease; LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg13012494 chr21:47604986 C21orf56 0.39 6.17 0.32 1.96e-9 Testicular germ cell tumor; LIHC cis rs12477438 0.684 rs6756880 chr2:99676991 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs2153535 0.541 rs9328477 chr6:8519109 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.68 0.42 1.64e-16 Motion sickness; LIHC cis rs7584330 0.554 rs7570873 chr2:238435054 G/A cg08992911 chr2:238395768 MLPH 0.49 5.95 0.31 6.48e-9 Prostate cancer; LIHC cis rs17021463 0.966 rs7657789 chr4:95178589 C/T cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.27 -0.45 2.08e-18 Testicular germ cell tumor; LIHC cis rs12701220 0.503 rs12531999 chr7:1181601 T/A cg02733842 chr7:1102375 C7orf50 -0.68 -7.14 -0.36 5.82e-12 Bronchopulmonary dysplasia; LIHC cis rs8064299 0.565 rs12453550 chr17:72786086 G/T cg25054828 chr17:72772726 NAT9;TMEM104 0.83 15.24 0.64 2.18e-40 Monocyte count; LIHC cis rs8017423 0.967 rs55667096 chr14:90714798 C/T cg04374321 chr14:90722782 PSMC1 0.75 14.54 0.62 1.23e-37 Mortality in heart failure; LIHC cis rs9790314 0.747 rs9990242 chr3:160838461 T/C cg03342759 chr3:160939853 NMD3 -0.68 -8.31 -0.41 2.36e-15 Morning vs. evening chronotype; LIHC cis rs1555322 0.530 rs2425049 chr20:33874720 C/T cg08210727 chr20:33865349 NA 0.49 5.72 0.3 2.36e-8 Attention deficit hyperactivity disorder; LIHC cis rs12824058 0.831 rs12831363 chr12:130814013 C/T cg26677194 chr12:130822605 PIWIL1 -0.51 -7.17 -0.36 4.52e-12 Menopause (age at onset); LIHC cis rs9902453 0.757 rs12453308 chr17:28441604 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.61 9.33 0.45 1.36e-18 Coffee consumption (cups per day); LIHC cis rs4843747 0.636 rs11117358 chr16:88105053 T/A cg00677901 chr16:88017247 BANP 0.51 7.92 0.39 3.26e-14 Menopause (age at onset); LIHC cis rs7572733 0.576 rs1865586 chr2:198758868 C/T cg03934865 chr2:198174659 NA -0.46 -6.53 -0.33 2.44e-10 Dermatomyositis; LIHC cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg08280861 chr8:58055591 NA 0.57 6.76 0.34 6.09e-11 Developmental language disorder (linguistic errors); LIHC cis rs1167827 0.680 rs1167796 chr7:75173180 C/T cg04681579 chr7:75027559 TRIM73;TRIM74 0.46 6.62 0.34 1.35e-10 Body mass index;BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg11453546 chr21:43990049 SLC37A1 0.42 6.04 0.31 4.13e-9 Electroencephalogram traits; LIHC cis rs1494950 1.000 rs10084853 chr4:14973469 C/T cg12377275 chr4:15005593 CPEB2 -0.78 -6.69 -0.34 9e-11 Political ideology; LIHC cis rs12594515 1.000 rs12595137 chr15:45986105 G/T cg06207120 chr15:45996521 NA 0.34 6.64 0.34 1.27e-10 Waist circumference;Weight; LIHC cis rs5769707 0.967 rs5770585 chr22:50007874 G/A cg07959070 chr22:50026188 C22orf34 -0.32 -8.48 -0.42 6.96e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs4649203 0.954 rs10794648 chr1:24518206 C/T cg01960748 chr1:24522592 NA 0.44 6.95 0.35 1.81e-11 Psoriasis; LIHC cis rs1712517 0.904 rs4918007 chr10:105107470 G/A cg05636881 chr10:105038444 INA -0.43 -6.59 -0.34 1.67e-10 Migraine; LIHC cis rs7487075 0.554 rs7960819 chr12:46628782 T/C cg15584813 chr12:47219626 SLC38A4 0.31 5.72 0.3 2.32e-8 Itch intensity from mosquito bite; LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg09455208 chr3:40491958 NA -0.39 -7.8 -0.39 7.81e-14 Renal cell carcinoma; LIHC cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg12311636 chr6:118886798 C6orf204 -0.54 -6.26 -0.32 1.15e-9 Diastolic blood pressure; LIHC cis rs17401966 0.898 rs11582123 chr1:10303942 A/T cg15208524 chr1:10270712 KIF1B 0.4 6.08 0.31 3.22e-9 Hepatocellular carcinoma; LIHC cis rs10861342 1.000 rs7305712 chr12:105519188 A/T cg23923672 chr12:105501055 KIAA1033 -0.58 -7.71 -0.38 1.34e-13 IgG glycosylation; LIHC cis rs10744422 0.858 rs2292136 chr12:123339344 A/G cg18912006 chr12:123335444 HIP1R -0.64 -7.67 -0.38 1.78e-13 Schizophrenia; LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.12 0.4 8.4e-15 Height; LIHC cis rs2549003 0.870 rs10053046 chr5:131821558 A/G cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs4819052 0.840 rs914217 chr21:46698299 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 10.67 0.5 3.8e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4727027 0.933 rs62505074 chr7:148834780 C/T cg23583168 chr7:148888333 NA -0.73 -10.34 -0.49 5.46e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs67311347 1.000 rs28434528 chr3:40484893 A/G cg00656387 chr3:40428638 ENTPD3 0.42 7.02 0.35 1.21e-11 Renal cell carcinoma; LIHC cis rs7223966 1.000 rs1877316 chr17:61766880 C/A cg05941027 chr17:61774174 LIMD2 0.33 6.73 0.34 7.37e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7208859 0.623 rs9912283 chr17:29110373 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg10360139 chr7:1886902 MAD1L1 -0.4 -6.23 -0.32 1.38e-9 Bipolar disorder and schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07318088 chr6:90539243 CASP8AP2 0.41 6.41 0.33 4.81e-10 Cognitive function; LIHC cis rs7224685 0.569 rs7213885 chr17:4018489 T/A cg09695851 chr17:3907499 NA 0.59 6.8 0.35 4.58e-11 Type 2 diabetes; LIHC cis rs875971 0.520 rs2420597 chr7:65915986 A/G cg11764359 chr7:65958608 NA 0.83 14.41 0.61 4e-37 Aortic root size; LIHC cis rs10792665 0.934 rs11233382 chr11:82657221 G/T cg24227371 chr11:82718527 RAB30 0.3 7.03 0.36 1.13e-11 Obesity-related traits; LIHC cis rs7520050 0.933 rs12565042 chr1:46299110 C/A cg03146154 chr1:46216737 IPP -0.37 -5.98 -0.31 5.62e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4237845 0.735 rs11172375 chr12:58291574 G/C cg04478727 chr12:58166393 METTL1;FAM119B 0.45 6.28 0.32 1.05e-9 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg21782813 chr7:2030301 MAD1L1 0.5 8.72 0.43 1.25e-16 Bipolar disorder and schizophrenia; LIHC cis rs477692 0.517 rs871026 chr10:131293145 A/G cg05714579 chr10:131428358 MGMT -0.39 -6.05 -0.31 3.73e-9 Response to temozolomide; LIHC cis rs7246657 0.943 rs10415937 chr19:37830064 T/G cg23950597 chr19:37808831 NA -0.43 -5.89 -0.3 9.01e-9 Coronary artery calcification; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg12630522 chr1:45956424 TESK2 -0.42 -6.04 -0.31 3.99e-9 Eotaxin levels; LIHC cis rs6430585 0.583 rs61253125 chr2:136618178 T/C cg07169764 chr2:136633963 MCM6 1.34 22.96 0.78 3.03e-71 Corneal structure; LIHC cis rs7772486 0.790 rs6924159 chr6:146267873 A/G cg13319975 chr6:146136371 FBXO30 0.37 6.01 0.31 4.87e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2075371 0.897 rs1646743 chr7:134003451 C/A cg20476274 chr7:133979776 SLC35B4 0.68 11.43 0.53 7.35e-26 Mean platelet volume; LIHC cis rs7659604 0.540 rs10012775 chr4:122676878 T/C cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.51e-11 Type 2 diabetes; LIHC cis rs6456156 0.586 rs12203510 chr6:167473006 C/T cg12798992 chr6:167411361 FGFR1OP 0.43 6.75 0.34 6.52e-11 Primary biliary cholangitis; LIHC cis rs6918586 0.658 rs198828 chr6:26119459 G/A cg18357526 chr6:26021779 HIST1H4A -0.57 -8.41 -0.41 1.15e-15 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18776992 chr19:48113764 GLTSCR1 0.45 6.49 0.33 3.07e-10 Lung function (FEV1/FVC); LIHC cis rs1775715 0.678 rs2105360 chr10:32210198 C/T cg14930904 chr10:32216787 ARHGAP12 0.37 6.47 0.33 3.35e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs2032447 0.531 rs428469 chr6:25898624 G/A cg03517284 chr6:25882590 NA -1.06 -13.42 -0.59 2.72e-33 Intelligence (multi-trait analysis); LIHC trans rs8073060 0.660 rs58266733 chr17:34003812 A/T cg19694781 chr19:47549865 TMEM160 -1.25 -13.18 -0.58 2.36e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg24879335 chr3:133465180 TF -0.27 -6.0 -0.31 5.05e-9 Iron status biomarkers; LIHC cis rs8084351 0.568 rs6508190 chr18:50575723 A/G cg24270629 chr18:50823537 DCC 0.39 5.95 0.31 6.79e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs11098499 0.866 rs9995136 chr4:120286845 A/G cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs67478160 0.643 rs6576005 chr14:104292369 C/T cg01849466 chr14:104193079 ZFYVE21 -0.49 -8.37 -0.41 1.51e-15 Schizophrenia; LIHC cis rs7085104 0.684 rs7092690 chr10:104609365 T/C cg15744005 chr10:104629667 AS3MT -0.4 -8.94 -0.44 2.53e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC trans rs916888 0.779 rs199528 chr17:44843136 C/T cg13957321 chr17:43675089 NA 0.5 7.69 0.38 1.62e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2070488 0.804 rs13092164 chr3:38458533 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.28 0.55 5.73e-29 Electrocardiographic conduction measures; LIHC cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4843747 0.671 rs74729706 chr16:88104159 C/T cg00677901 chr16:88017247 BANP 0.52 8.03 0.4 1.58e-14 Menopause (age at onset); LIHC cis rs6060717 0.610 rs1891154 chr20:34617129 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -7.91 -0.39 3.49e-14 Hip circumference adjusted for BMI; LIHC cis rs10411936 0.692 rs10413787 chr19:16594967 A/G cg10248733 chr19:16607483 C19orf44;CALR3 0.52 6.95 0.35 1.81e-11 White blood cell count;Multiple sclerosis; LIHC trans rs1005277 0.579 rs2474568 chr10:38383147 A/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.24 -0.52 3.61e-25 Extrinsic epigenetic age acceleration; LIHC cis rs709400 0.930 rs2274268 chr14:104029378 C/G cg26031613 chr14:104095156 KLC1 1.12 14.3 0.61 1.05e-36 Body mass index; LIHC cis rs35110281 0.622 rs9977258 chr21:44976485 G/T cg04455712 chr21:45112962 RRP1B 0.42 6.98 0.35 1.51e-11 Mean corpuscular volume; LIHC cis rs1062177 1.000 rs2964576 chr5:151150602 T/G cg00977110 chr5:151150581 G3BP1 0.56 7.11 0.36 6.8e-12 Preschool internalizing problems; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg26338869 chr17:61819248 STRADA 0.56 8.1 0.4 9.86e-15 Prudent dietary pattern; LIHC cis rs12478296 1.000 rs6743297 chr2:243013814 A/G cg06360820 chr2:242988706 NA -0.79 -11.66 -0.53 1.09e-26 Obesity-related traits; LIHC cis rs2806561 0.734 rs10799788 chr1:23356864 G/A cg12483005 chr1:23474871 LUZP1 0.46 7.01 0.35 1.31e-11 Height; LIHC cis rs17401966 0.965 rs12751375 chr1:10291874 C/G cg19773385 chr1:10388646 KIF1B -0.47 -8.1 -0.4 9.72e-15 Hepatocellular carcinoma; LIHC cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.83 8.18 0.4 5.73e-15 Platelet count; LIHC cis rs34172651 0.517 rs11642954 chr16:24824248 G/A cg04756594 chr16:24857601 SLC5A11 0.62 9.04 0.44 1.18e-17 Intelligence (multi-trait analysis); LIHC cis rs3020736 0.500 rs4147638 chr22:42487900 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.08 -0.31 3.15e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs55665837 1.000 rs10832271 chr11:14466919 C/G cg19336497 chr11:14380999 RRAS2 -0.45 -8.29 -0.41 2.53e-15 Vitamin D levels; LIHC cis rs4819052 0.851 rs8130285 chr21:46671701 G/C cg11663144 chr21:46675770 NA -0.31 -5.83 -0.3 1.26e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9303280 0.773 rs4795397 chr17:38023745 A/G cg11212589 chr17:38028394 ZPBP2 0.34 6.8 0.35 4.59e-11 Self-reported allergy; LIHC cis rs2153535 0.601 rs9328487 chr6:8529378 G/C cg21535247 chr6:8435926 SLC35B3 0.65 8.63 0.42 2.43e-16 Motion sickness; LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC cis rs2836974 0.666 rs1888487 chr21:40683259 A/G cg17971929 chr21:40555470 PSMG1 -0.48 -7.05 -0.36 1.01e-11 Cognitive function; LIHC cis rs7833986 0.501 rs17814658 chr8:56989130 T/C cg23139584 chr8:56987506 RPS20;SNORD54 0.82 8.36 0.41 1.62e-15 Height; LIHC cis rs4908760 0.965 rs1884352 chr1:8537289 G/A cg20416874 chr1:8611966 RERE -0.67 -14.22 -0.61 2.28e-36 Vitiligo; LIHC cis rs611744 0.647 rs6981420 chr8:109266694 T/G cg21045802 chr8:109455806 TTC35 0.59 10.37 0.49 4.22e-22 Dupuytren's disease; LIHC cis rs9326778 0.520 rs10077438 chr5:108827962 C/A cg17395555 chr5:108820864 NA -0.36 -6.13 -0.31 2.48e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC trans rs2262909 0.925 rs56073035 chr19:22276298 C/G cg05197062 chr11:11642011 GALNTL4 0.45 6.61 0.34 1.48e-10 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg12311346 chr5:56204834 C5orf35 -0.56 -7.36 -0.37 1.38e-12 Initial pursuit acceleration; LIHC trans rs837841 0.864 rs1660903 chr2:130046679 C/G ch.11.1111744F chr11:58378857 ZFP91;ZFP91-CNTF 0.33 6.13 0.31 2.49e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel); LIHC cis rs10193935 0.901 rs6544549 chr2:42693056 C/T cg27598129 chr2:42591480 NA 0.71 9.12 0.44 6.34e-18 Colonoscopy-negative controls vs population controls; LIHC cis rs2549003 1.000 rs2070724 chr5:131822072 A/G cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07415654 chr3:15797850 ANKRD28 -0.47 -6.07 -0.31 3.44e-9 Hepatitis; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg27050550 chr7:44613552 DDX56 -0.48 -6.28 -0.32 1.01e-9 Lung function (FEV1); LIHC cis rs10751667 1.000 rs7927156 chr11:970607 A/G ch.11.42038R chr11:967971 AP2A2 0.55 9.79 0.47 4.08e-20 Alzheimer's disease (late onset); LIHC cis rs11955398 0.716 rs2061250 chr5:59917678 C/A cg02684056 chr5:59996105 DEPDC1B 0.41 6.09 0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg18538332 chr22:24372958 LOC391322 -0.66 -9.78 -0.47 4.28e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6502050 0.799 rs9911129 chr17:80087819 C/T cg11859384 chr17:80120422 CCDC57 -0.42 -5.74 -0.3 2.06e-8 Life satisfaction; LIHC cis rs1005277 0.563 rs2800550 chr10:38482929 T/C cg00409905 chr10:38381863 ZNF37A -0.57 -9.48 -0.46 4.29e-19 Extrinsic epigenetic age acceleration; LIHC cis rs10463316 0.817 rs1810083 chr5:150776807 A/G cg03212797 chr5:150827313 SLC36A1 0.41 6.12 0.31 2.58e-9 Metabolite levels (Pyroglutamine); LIHC cis rs2637266 1.000 rs7896831 chr10:78366649 A/T cg18941641 chr10:78392320 NA 0.27 5.72 0.3 2.35e-8 Pulmonary function; LIHC cis rs1577917 0.696 rs10806334 chr6:86439329 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -7.2 -0.36 3.96e-12 Response to antipsychotic treatment; LIHC cis rs7296418 0.663 rs11057276 chr12:123820397 C/T cg00376283 chr12:123451042 ABCB9 -0.61 -10.14 -0.48 2.78e-21 Platelet count; LIHC cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg22907277 chr7:1156413 C7orf50 0.74 5.85 0.3 1.14e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg05064044 chr6:292385 DUSP22 -0.52 -6.96 -0.35 1.79e-11 Menopause (age at onset); LIHC cis rs992157 0.710 rs56364928 chr2:219059058 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.15 0.58 3.08e-32 Colorectal cancer; LIHC cis rs963731 0.649 rs4670272 chr2:39260468 A/C cg04010122 chr2:39346883 SOS1 -0.68 -6.11 -0.31 2.73e-9 Corticobasal degeneration; LIHC cis rs6570726 0.791 rs9403730 chr6:145907233 C/T cg23711669 chr6:146136114 FBXO30 0.71 12.15 0.55 1.79e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs8103278 0.793 rs59093775 chr19:46374037 G/A cg14061069 chr19:46274453 DMPK -0.49 -7.28 -0.37 2.37e-12 Coronary artery disease; LIHC cis rs2412488 1.000 rs17082782 chr4:54306440 A/T cg22241045 chr4:54363911 LNX1 -0.46 -7.29 -0.37 2.23e-12 DNA methylation (variation); LIHC cis rs904251 0.600 rs2270687 chr6:37418263 A/G cg01843034 chr6:37503916 NA -0.38 -6.13 -0.31 2.39e-9 Cognitive performance; LIHC trans rs1005277 0.540 rs1987431 chr10:37988887 T/C cg17830980 chr10:43048298 ZNF37B -0.42 -8.09 -0.4 1.08e-14 Extrinsic epigenetic age acceleration; LIHC cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg06453172 chr10:134556979 INPP5A -0.62 -8.23 -0.41 3.99e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2180341 0.843 rs4895821 chr6:127572761 T/A cg27446573 chr6:127587934 RNF146 0.93 14.8 0.62 1.14e-38 Breast cancer; LIHC cis rs2758596 1.000 rs2241111 chr1:156163718 T/C cg24450063 chr1:156163899 SLC25A44 1.0 9.95 0.47 1.23e-20 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs9399135 0.967 rs10872427 chr6:135353452 T/C cg24558204 chr6:135376177 HBS1L 0.43 7.15 0.36 5.21e-12 Red blood cell count; LIHC cis rs2346177 0.519 rs2121698 chr2:46709571 C/T cg02822958 chr2:46747628 ATP6V1E2 0.52 7.86 0.39 5.11e-14 HDL cholesterol; LIHC cis rs7116495 0.609 rs7111379 chr11:71826319 C/T cg26138937 chr11:71823887 C11orf51 1.32 10.9 0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs7520050 0.966 rs785485 chr1:46574424 C/T cg03146154 chr1:46216737 IPP -0.37 -6.21 -0.32 1.57e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.69 11.35 0.52 1.49e-25 Age at first birth; LIHC cis rs12579753 0.879 rs11115007 chr12:82164673 A/T cg07988820 chr12:82153109 PPFIA2 -0.5 -6.25 -0.32 1.2e-9 Resting heart rate; LIHC cis rs6665290 0.904 rs11586604 chr1:227183865 G/T cg10327440 chr1:227177885 CDC42BPA -1.19 -31.38 -0.86 1.02e-102 Myeloid white cell count; LIHC cis rs6500602 0.702 rs56895104 chr16:4548132 G/A cg08645402 chr16:4508243 NA 0.45 8.81 0.43 6.38e-17 Schizophrenia; LIHC cis rs1707322 1.000 rs785519 chr1:46568562 C/T cg03146154 chr1:46216737 IPP -0.45 -7.26 -0.37 2.61e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs5753037 0.543 rs131268 chr22:30147938 C/G cg01021169 chr22:30184971 ASCC2 -0.31 -5.87 -0.3 1.02e-8 Type 1 diabetes; LIHC cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg23205692 chr1:25664452 TMEM50A 0.39 6.18 0.32 1.83e-9 Erythrocyte sedimentation rate; LIHC cis rs6062302 0.522 rs13043255 chr20:62218916 C/G cg06363034 chr20:62225388 GMEB2 -0.42 -7.29 -0.37 2.15e-12 Glioblastoma; LIHC cis rs6752107 0.503 rs12997325 chr2:234237387 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.44 6.49 0.33 2.95e-10 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2274273 0.661 rs8019978 chr14:55557284 A/G cg01864836 chr14:55583639 NA 0.36 6.7 0.34 8.39e-11 Protein biomarker; LIHC cis rs6121246 0.529 rs6060359 chr20:30209740 A/G cg13852791 chr20:30311386 BCL2L1 0.77 6.75 0.34 6.51e-11 Mean corpuscular hemoglobin; LIHC trans rs2243480 1.000 rs34815098 chr7:65292254 A/C cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs8180040 0.726 rs10461018 chr3:46995242 C/T cg16586182 chr3:47516702 SCAP 0.47 8.43 0.41 9.62e-16 Colorectal cancer; LIHC cis rs2806561 0.577 rs488438 chr1:23498999 T/A cg19743168 chr1:23544995 NA 0.35 5.79 0.3 1.62e-8 Height; LIHC cis rs1419980 0.643 rs12228661 chr12:7745882 C/G cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs12744310 0.887 rs12047272 chr1:41801943 G/A cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs875971 0.895 rs3857684 chr7:65938158 G/C cg11764359 chr7:65958608 NA 0.91 16.81 0.67 1.25e-46 Aortic root size; LIHC trans rs61931739 0.500 rs7303318 chr12:34467789 T/C cg26384229 chr12:38710491 ALG10B 0.64 8.11 0.4 9.42e-15 Morning vs. evening chronotype; LIHC cis rs2842992 0.662 rs2273825 chr6:160211424 A/C cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03193865 chr8:145510099 BOP1 -0.41 -6.28 -0.32 1.01e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.5 0.56 8.64e-30 Alzheimer's disease; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg27411370 chr8:25316735 KCTD9;CDCA2 -0.54 -6.28 -0.32 1.04e-9 Obesity-related traits; LIHC cis rs921968 0.643 rs497983 chr2:219415189 A/G cg02985541 chr2:219472218 PLCD4 0.46 8.61 0.42 2.77e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs17376456 1.000 rs17376207 chr5:93545524 C/T cg25358565 chr5:93447407 FAM172A -1.04 -9.5 -0.46 3.86e-19 Diabetic retinopathy; LIHC cis rs11098499 0.954 rs10024844 chr4:120311528 A/G cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs6963495 0.745 rs73192152 chr7:105212258 A/C cg19920283 chr7:105172520 RINT1 0.66 5.94 0.31 6.91e-9 Bipolar disorder (body mass index interaction); LIHC cis rs4919087 1.000 rs4919091 chr10:99088682 A/T cg25902810 chr10:99078978 FRAT1 -0.65 -9.59 -0.46 1.84e-19 Monocyte count; LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg07677032 chr17:61819896 STRADA 0.41 6.07 0.31 3.32e-9 Prudent dietary pattern; LIHC cis rs7927592 0.913 rs6591344 chr11:68360873 G/A cg01657329 chr11:68192670 LRP5 -0.48 -6.22 -0.32 1.46e-9 Total body bone mineral density; LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.15 0.55 1.69e-28 Height; LIHC cis rs1005277 0.522 rs9418276 chr10:37940116 G/T cg25427524 chr10:38739819 LOC399744 -0.61 -11.58 -0.53 2.16e-26 Extrinsic epigenetic age acceleration; LIHC cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg26831259 chr4:1366826 KIAA1530 0.35 5.75 0.3 1.99e-8 Obesity-related traits; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs2795502 1.000 rs3121323 chr10:43377166 A/G cg20628663 chr10:43360327 NA -0.44 -6.87 -0.35 3.07e-11 Blood protein levels; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg24846343 chr22:24311635 DDTL 0.64 12.18 0.55 1.37e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7914558 1.000 rs10786733 chr10:104794947 G/A cg15744005 chr10:104629667 AS3MT -0.36 -8.11 -0.4 9.32e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2143950 0.607 rs58770366 chr14:35528023 A/G cg16230307 chr14:35515116 FAM177A1 -0.39 -6.35 -0.32 6.69e-10 Atopic dermatitis; LIHC cis rs1865721 0.771 rs4410169 chr18:73138840 A/G cg26385618 chr18:73139727 C18orf62 -0.32 -8.58 -0.42 3.37e-16 Intelligence; LIHC trans rs5756813 0.688 rs12484064 chr22:38126746 C/A cg19894588 chr14:64061835 NA -0.61 -7.84 -0.39 5.74e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs2153535 0.580 rs7341383 chr6:8470634 A/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01839850 chr22:38240395 ANKRD54;MIR658 0.41 6.87 0.35 3.11e-11 Cognitive function; LIHC cis rs61677309 0.597 rs112590920 chr11:118143586 G/A cg06090739 chr11:118230722 UBE4A 0.32 6.03 0.31 4.34e-9 Lung cancer in ever smokers; LIHC cis rs17345786 0.906 rs11710016 chr3:101120030 A/C cg12386194 chr3:101231763 SENP7 -0.58 -7.54 -0.38 4.19e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs172166 0.694 rs188105 chr6:28071393 C/T cg23485639 chr6:28045615 ZNF165 0.39 6.05 0.31 3.78e-9 Cardiac Troponin-T levels; LIHC cis rs4759375 1.000 rs7312145 chr12:123825339 A/G cg00376283 chr12:123451042 ABCB9 0.5 6.37 0.33 6.18e-10 HDL cholesterol; LIHC cis rs919433 0.680 rs2124317 chr2:198477606 G/A cg10820045 chr2:198174542 NA 0.51 7.99 0.4 2.06e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8067545 0.750 rs11868084 chr17:19992717 A/G cg13482628 chr17:19912719 NA 0.49 8.12 0.4 8.43e-15 Schizophrenia; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6905237 chr6:8471790 A/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs9790314 0.521 rs2122527 chr3:161091636 G/A cg03342759 chr3:160939853 NMD3 -0.43 -6.38 -0.33 5.59e-10 Morning vs. evening chronotype; LIHC cis rs1865760 0.566 rs2858993 chr6:26087856 T/A cg18357526 chr6:26021779 HIST1H4A 0.44 6.4 0.33 5.18e-10 Height; LIHC cis rs769267 0.930 rs7254748 chr19:19397479 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.6 9.48 0.46 4.3e-19 Tonsillectomy; LIHC cis rs4423214 0.592 rs10898186 chr11:71188800 G/A cg05163923 chr11:71159392 DHCR7 -0.59 -7.35 -0.37 1.44e-12 Vitamin D levels; LIHC cis rs9916302 0.851 rs9909064 chr17:37500434 G/T cg03013999 chr17:37608204 MED1 -0.35 -5.93 -0.31 7.41e-9 Glomerular filtration rate (creatinine); LIHC cis rs9633740 1.000 rs1870137 chr10:82269848 C/G cg01528321 chr10:82214614 TSPAN14 0.93 11.43 0.53 7.91e-26 Post bronchodilator FEV1; LIHC cis rs7617773 0.823 rs9839447 chr3:48194667 T/C cg11946769 chr3:48343235 NME6 -0.65 -8.3 -0.41 2.51e-15 Coronary artery disease; LIHC cis rs748404 0.697 rs572959 chr15:43550502 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.43 6.55 0.33 2.08e-10 Lung cancer; LIHC cis rs7927592 0.913 rs67605986 chr11:68300955 C/T cg20283391 chr11:68216788 NA -0.52 -7.8 -0.39 7.74e-14 Total body bone mineral density; LIHC cis rs4268898 0.662 rs35624938 chr2:24576651 T/C cg06627628 chr2:24431161 ITSN2 -0.74 -9.62 -0.46 1.53e-19 Asthma; LIHC cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg17328964 chr8:145687451 CYHR1 0.46 7.53 0.38 4.68e-13 Age at first birth; LIHC cis rs12497850 0.931 rs13316620 chr3:49045355 T/C cg07636037 chr3:49044803 WDR6 0.95 17.19 0.68 3.62e-48 Parkinson's disease; LIHC cis rs797680 0.856 rs797681 chr1:93717746 T/C cg15093775 chr1:93646470 TMED5;CCDC18 0.34 5.96 0.31 6.39e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs4773330 1.000 rs3809341 chr13:111805412 G/A cg26911804 chr13:111806221 ARHGEF7 0.6 5.88 0.3 9.6e-9 Bilirubin levels; LIHC cis rs6500602 0.739 rs4786502 chr16:4537104 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.25 0.32 1.22e-9 Schizophrenia; LIHC cis rs6089584 0.893 rs6089305 chr20:60571817 T/C cg12751644 chr20:60527061 NA -0.37 -6.24 -0.32 1.28e-9 Body mass index; LIHC cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg20887711 chr4:1340912 KIAA1530 -0.77 -11.23 -0.52 3.96e-25 Longevity; LIHC cis rs2153535 0.601 rs9406160 chr6:8464907 A/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs6594499 0.872 rs10038177 chr5:110436450 C/T cg04022379 chr5:110408740 TSLP 0.5 8.25 0.41 3.45e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg20818283 chr2:191399100 TMEM194B 0.47 6.32 0.32 8.34e-10 Pulse pressure; LIHC cis rs2380220 0.808 rs2380224 chr6:95895553 C/T cg04719120 chr6:96025338 MANEA -0.56 -6.01 -0.31 4.64e-9 Behavioural disinhibition (generation interaction); LIHC cis rs778371 0.723 rs11689851 chr2:233567342 A/G cg08000102 chr2:233561755 GIGYF2 0.75 8.95 0.44 2.35e-17 Schizophrenia; LIHC cis rs2408955 0.561 rs9971924 chr12:48479832 C/G cg21466736 chr12:48725269 NA 0.62 9.0 0.44 1.57e-17 Glycated hemoglobin levels; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs3106136 0.967 rs2129595 chr4:95224454 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.9 -0.39 3.77e-14 Capecitabine sensitivity; LIHC cis rs12887734 0.566 rs8548 chr14:104199580 A/C cg01849466 chr14:104193079 ZFYVE21 -0.4 -5.93 -0.31 7.39e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2016586 0.929 rs8136429 chr22:36111828 C/G cg26342177 chr22:36113512 APOL5 -0.38 -6.3 -0.32 9.32e-10 Body mass index; LIHC cis rs7523273 0.565 rs2104303 chr1:207886684 C/T cg22525895 chr1:207977042 MIR29B2 -0.52 -7.75 -0.39 1.09e-13 Schizophrenia; LIHC cis rs17685 0.712 rs7785025 chr7:75628101 C/T cg04610667 chr7:75704037 NA 0.33 5.94 0.31 7.16e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs881375 0.934 rs1468671 chr9:123657502 C/G cg14580859 chr9:123691850 NA 0.36 6.01 0.31 4.83e-9 Rheumatoid arthritis; LIHC cis rs6723226 0.767 rs10172308 chr2:32555760 G/A cg02381751 chr2:32503542 YIPF4 -0.8 -12.52 -0.56 7.6e-30 Intelligence (multi-trait analysis); LIHC cis rs2016586 0.647 rs5999943 chr22:36092836 C/G cg26342177 chr22:36113512 APOL5 -0.36 -5.92 -0.31 7.7e-9 Body mass index; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg06601766 chr17:61851465 DDX42;CCDC47 -0.49 -7.57 -0.38 3.57e-13 Prudent dietary pattern; LIHC cis rs763014 0.966 rs12935215 chr16:670605 T/C cg09256448 chr16:638327 NA 0.38 6.25 0.32 1.25e-9 Height; LIHC cis rs875971 0.660 rs28698552 chr7:66005018 A/G cg11764359 chr7:65958608 NA 0.72 10.98 0.51 3.13e-24 Aortic root size; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg18934136 chr17:55927456 MRPS23 -0.45 -6.2 -0.32 1.65e-9 Alopecia areata; LIHC cis rs644799 0.710 rs564480 chr11:95561741 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.75 13.05 0.58 7.11e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg26939375 chr7:64535504 NA 0.44 7.48 0.37 6.5e-13 Calcium levels; LIHC cis rs8180040 0.764 rs4683324 chr3:47251284 T/C cg16586182 chr3:47516702 SCAP -0.52 -9.48 -0.46 4.55e-19 Colorectal cancer; LIHC cis rs892961 0.932 rs3987886 chr17:75414980 A/G cg05865280 chr17:75406074 SEPT9 0.63 12.73 0.57 1.19e-30 Airflow obstruction; LIHC cis rs3740540 0.507 rs942015 chr10:126289932 G/T cg04949429 chr10:126290192 LHPP 0.45 7.26 0.37 2.55e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs9921222 0.597 rs3848369 chr16:415078 C/T cg26944245 chr16:421049 TMEM8A;MRPL28 0.41 7.35 0.37 1.44e-12 Bone mineral density (spine);Bone mineral density; LIHC trans rs7537660 1.000 rs7522811 chr1:248005213 C/G cg07583490 chr19:15375374 BRD4 0.65 6.11 0.31 2.66e-9 Platelet distribution width; LIHC cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs7647973 1.000 rs7648995 chr3:49438803 C/T cg07636037 chr3:49044803 WDR6 -0.53 -6.44 -0.33 4.07e-10 Menarche (age at onset); LIHC cis rs9341808 0.935 rs1535825 chr6:80938586 C/T cg08355045 chr6:80787529 NA -0.32 -6.2 -0.32 1.6e-9 Sitting height ratio; LIHC cis rs12497850 0.931 rs6446196 chr3:49004723 A/G cg07636037 chr3:49044803 WDR6 0.93 16.31 0.66 1.25e-44 Parkinson's disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg22691340 chr12:62997631 C12orf61 0.4 6.05 0.31 3.74e-9 Calcium levels; LIHC cis rs1348850 0.651 rs4893936 chr2:178240676 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.81 12.47 0.56 1.1e-29 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23590525 chr1:1469787 ATAD3A 0.36 6.05 0.31 3.91e-9 Pancreatic cancer; LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg02782426 chr3:40428986 ENTPD3 0.34 6.4 0.33 5.16e-10 Renal cell carcinoma; LIHC trans rs9929218 1.000 rs7186084 chr16:68816260 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 7.32 0.37 1.8e-12 Colorectal cancer; LIHC cis rs2979489 0.891 rs2915592 chr8:30396417 C/T cg26383811 chr8:30366931 RBPMS -0.71 -11.78 -0.54 3.95e-27 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs765787 0.530 rs4774542 chr15:45526026 A/C cg26924012 chr15:45694286 SPATA5L1 0.41 6.25 0.32 1.22e-9 Uric acid levels; LIHC cis rs6952808 0.595 rs2398705 chr7:2164995 G/A cg20295408 chr7:1910781 MAD1L1 -0.42 -6.09 -0.31 3.01e-9 Bipolar disorder and schizophrenia; LIHC cis rs2997447 0.846 rs72886619 chr1:26452604 G/A cg19633962 chr1:26362018 EXTL1 -0.65 -5.96 -0.31 6.43e-9 QRS complex (12-leadsum); LIHC cis rs11105298 0.685 rs117578503 chr12:89836672 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.37 -0.37 1.25e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs9921222 0.597 rs3848369 chr16:415078 C/T cg26913058 chr16:419975 MRPL28 -0.62 -9.36 -0.45 1.1e-18 Bone mineral density (spine);Bone mineral density; LIHC cis rs2075371 1.000 rs2244694 chr7:133987093 C/T cg20476274 chr7:133979776 SLC35B4 0.75 12.53 0.56 6.44e-30 Mean platelet volume; LIHC cis rs7100689 0.615 rs10788639 chr10:82233225 C/G cg01528321 chr10:82214614 TSPAN14 0.54 7.54 0.38 4.14e-13 Post bronchodilator FEV1; LIHC trans rs1814175 0.791 rs10839468 chr11:49986288 A/G cg18944383 chr4:111397179 ENPEP 0.27 7.08 0.36 8.16e-12 Height; LIHC cis rs826838 0.967 rs2892410 chr12:38990282 A/G cg26384229 chr12:38710491 ALG10B -0.91 -12.3 -0.55 4.8e-29 Heart rate; LIHC cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg13395646 chr4:1353034 KIAA1530 -0.65 -9.37 -0.45 1.05e-18 Obesity-related traits; LIHC cis rs4474465 0.646 rs10793335 chr11:78279005 C/G cg02023728 chr11:77925099 USP35 -0.34 -6.01 -0.31 4.72e-9 Alzheimer's disease (survival time); LIHC cis rs9388451 0.626 rs7748729 chr6:126077381 C/T cg05901451 chr6:126070800 HEY2 -0.67 -14.07 -0.61 8.23e-36 Brugada syndrome; LIHC cis rs2228479 0.618 rs17233623 chr16:89811209 C/T cg04013166 chr16:89971882 TCF25 0.51 6.45 0.33 3.75e-10 Skin colour saturation; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04575144 chr19:4067379 ZBTB7A 0.4 6.08 0.31 3.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6939532 0.597 rs2273558 chr6:26466035 A/C cg12826209 chr6:26865740 GUSBL1 0.49 6.22 0.32 1.47e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7267979 1.000 rs2297497 chr20:25297909 C/T cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.65 -0.34 1.14e-10 Liver enzyme levels (alkaline phosphatase); LIHC cis rs11864453 0.762 rs6416742 chr16:72149061 C/T cg01557791 chr16:72042693 DHODH -0.51 -8.01 -0.4 1.77e-14 Fibrinogen levels; LIHC cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg23806715 chr17:73775811 H3F3B 0.53 7.19 0.36 3.98e-12 Psoriasis; LIHC cis rs1790761 0.692 rs1148883 chr11:67304686 A/G cg21734168 chr11:67353974 GSTP1 -0.26 -6.5 -0.33 2.91e-10 Mean corpuscular volume; LIHC cis rs7659604 0.537 rs6815973 chr4:122663430 A/T cg19748678 chr4:122722346 EXOSC9 -0.43 -6.45 -0.33 3.93e-10 Type 2 diabetes; LIHC cis rs6089584 0.566 rs11699442 chr20:60623268 A/G cg23262073 chr20:60523788 NA -0.29 -6.15 -0.32 2.15e-9 Body mass index; LIHC cis rs5769707 0.616 rs6009786 chr22:50015145 A/G cg01652190 chr22:50026171 C22orf34 -0.34 -7.62 -0.38 2.46e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs748404 0.660 rs2439846 chr15:43740970 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.11e-13 Lung cancer; LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg15586393 chr4:1244086 CTBP1;C4orf42 -0.41 -5.82 -0.3 1.33e-8 Longevity; LIHC cis rs4474465 1.000 rs10899520 chr11:78183370 C/T cg27205649 chr11:78285834 NARS2 -0.38 -5.78 -0.3 1.68e-8 Alzheimer's disease (survival time); LIHC cis rs7086627 0.515 rs4933390 chr10:82213081 A/C cg00277334 chr10:82204260 NA -0.85 -13.98 -0.6 2.01e-35 Post bronchodilator FEV1; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg22920498 chr9:19103109 HAUS6 -0.37 -6.12 -0.31 2.49e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6598163 0.564 rs12319878 chr12:132289989 C/T cg02426739 chr12:132285352 NA 0.36 5.78 0.3 1.72e-8 Migraine; LIHC cis rs10751667 0.600 rs4076915 chr11:1012464 C/G ch.11.42038R chr11:967971 AP2A2 0.59 10.83 0.51 1.03e-23 Alzheimer's disease (late onset); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg08123528 chr3:72438132 RYBP -0.29 -6.7 -0.34 8.38e-11 Calcium levels; LIHC cis rs763121 0.889 rs1837988 chr22:38901094 A/G cg06022373 chr22:39101656 GTPBP1 0.62 10.33 0.49 5.98e-22 Menopause (age at onset); LIHC cis rs35883536 1.000 rs6663612 chr1:101085835 A/G cg14515779 chr1:101123966 NA -0.61 -10.39 -0.49 3.8e-22 Monocyte count; LIHC cis rs2075165 0.935 rs933489 chr1:156235120 T/C cg07234388 chr1:156261841 TMEM79 0.5 8.92 0.43 2.97e-17 Tonsillectomy; LIHC cis rs3806843 0.966 rs7737424 chr5:140146345 C/T cg19875535 chr5:140030758 IK 0.37 5.98 0.31 5.72e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs7615952 0.673 rs34209763 chr3:125599595 G/A cg07211511 chr3:129823064 LOC729375 -0.82 -8.86 -0.43 4.39e-17 Blood pressure (smoking interaction); LIHC cis rs8083850 0.635 rs2195722 chr18:50861536 G/T cg24270629 chr18:50823537 DCC -0.56 -8.62 -0.42 2.62e-16 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg06238570 chr21:40685208 BRWD1 -0.53 -8.77 -0.43 8.46e-17 Cognitive function; LIHC cis rs1538970 0.924 rs12097497 chr1:45880669 C/T cg05343316 chr1:45956843 TESK2 0.58 8.53 0.42 4.98e-16 Platelet count; LIHC cis rs8062405 0.964 rs7187333 chr16:28865916 G/A cg16576597 chr16:28551801 NUPR1 0.37 5.83 0.3 1.26e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs1005277 0.522 rs289648 chr10:37971837 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.31 0.32 8.81e-10 Extrinsic epigenetic age acceleration; LIHC cis rs1451375 0.583 rs3807556 chr7:50610536 G/A cg14593290 chr7:50529359 DDC 0.63 9.81 0.47 3.41e-20 Malaria; LIHC cis rs34779708 0.966 rs7070427 chr10:35485689 A/T cg04310649 chr10:35416472 CREM -0.43 -5.8 -0.3 1.5e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9359856 0.529 rs72919916 chr6:90489773 G/A cg13799429 chr6:90582589 CASP8AP2 -0.68 -6.06 -0.31 3.5e-9 Bipolar disorder; LIHC cis rs11758351 0.866 rs2022448 chr6:26207928 C/T cg06951627 chr6:26196580 NA 0.46 5.92 0.3 7.96e-9 Gout;Renal underexcretion gout; LIHC trans rs9929218 0.679 rs9924886 chr16:68743939 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -9.1 -0.44 7.85e-18 Colorectal cancer; LIHC cis rs11628318 0.853 rs7155171 chr14:103031845 C/T cg23461800 chr14:103021989 NA -0.48 -6.87 -0.35 3.13e-11 Platelet count; LIHC cis rs7587476 0.784 rs17424051 chr2:215688992 G/C cg04004882 chr2:215674386 BARD1 0.57 7.87 0.39 4.65e-14 Neuroblastoma; LIHC cis rs10751667 0.600 rs4076915 chr11:1012464 C/G cg10932868 chr11:921992 NA 0.31 5.8 0.3 1.52e-8 Alzheimer's disease (late onset); LIHC trans rs6598955 0.671 rs11579630 chr1:26612297 C/A cg07461501 chr17:79650226 HGS;ARL16 -0.75 -8.73 -0.43 1.14e-16 Obesity-related traits; LIHC cis rs2070488 1.000 rs36006749 chr3:38443312 T/C cg24069376 chr3:38537580 EXOG 0.41 7.52 0.38 4.73e-13 Electrocardiographic conduction measures; LIHC cis rs1023500 0.505 rs134874 chr22:42661144 A/G cg04733989 chr22:42467013 NAGA 0.4 6.2 0.32 1.64e-9 Schizophrenia; LIHC cis rs1451375 0.617 rs2329371 chr7:50615440 G/A cg14593290 chr7:50529359 DDC 0.63 9.96 0.47 1.09e-20 Malaria; LIHC cis rs963731 0.579 rs11692687 chr2:39265428 A/G cg04010122 chr2:39346883 SOS1 -0.68 -6.11 -0.31 2.73e-9 Corticobasal degeneration; LIHC cis rs9790314 0.765 rs4856768 chr3:161004392 G/A cg03342759 chr3:160939853 NMD3 -0.74 -10.62 -0.5 6.09e-23 Morning vs. evening chronotype; LIHC cis rs1843834 0.539 rs2068244 chr2:225440011 A/G cg22455342 chr2:225449267 CUL3 -0.53 -7.5 -0.38 5.65e-13 IgE levels in asthmatics (D.p. specific); LIHC cis rs6088580 0.634 rs6142164 chr20:33006597 C/T cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs11792861 0.926 rs72607173 chr9:111879398 T/G cg13535736 chr9:111863775 C9orf5 -0.38 -5.84 -0.3 1.19e-8 Menarche (age at onset); LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg16145915 chr7:1198662 ZFAND2A -0.43 -11.5 -0.53 4.13e-26 Longevity;Endometriosis; LIHC trans rs4843747 0.671 rs28465438 chr16:88103714 G/A cg26811252 chr16:29126840 RRN3P2 0.44 7.23 0.36 3.14e-12 Menopause (age at onset); LIHC cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.84 -10.86 -0.51 8.38e-24 Alzheimer's disease; LIHC cis rs16944613 0.510 rs8035793 chr15:91150084 C/T cg26821196 chr15:91095069 CRTC3 0.32 5.99 0.31 5.42e-9 Colorectal cancer; LIHC cis rs2637266 0.756 rs7079818 chr10:78469935 T/A cg18941641 chr10:78392320 NA 0.28 5.97 0.31 5.82e-9 Pulmonary function; LIHC cis rs11674184 0.525 rs4669755 chr2:11748585 A/C cg07314298 chr2:11723111 GREB1 0.43 7.35 0.37 1.47e-12 Endometriosis; LIHC cis rs1559088 0.901 rs12610053 chr19:33582606 A/G cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18075073 chr11:210610 RIC8A 0.41 6.37 0.33 6.22e-10 Pancreatic cancer; LIHC cis rs10411936 0.720 rs2885706 chr19:16582937 C/A cg10248733 chr19:16607483 C19orf44;CALR3 0.48 6.41 0.33 4.78e-10 White blood cell count;Multiple sclerosis; LIHC cis rs3008870 1.000 rs35365746 chr1:67438900 G/A cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs9918079 0.560 rs4557256 chr4:15626647 A/C cg21123203 chr4:15471301 CC2D2A -0.46 -7.32 -0.37 1.79e-12 Obesity-related traits; LIHC cis rs9486719 1.000 rs926276 chr6:96868735 C/T cg06623918 chr6:96969491 KIAA0776 0.7 7.85 0.39 5.45e-14 Migraine;Coronary artery disease; LIHC cis rs559928 0.606 rs55942618 chr11:63936005 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.4 0.37 1.09e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs9326248 0.954 rs10790177 chr11:117048417 A/G cg15534755 chr11:117069859 TAGLN 0.36 6.18 0.32 1.78e-9 Blood protein levels; LIHC cis rs3008870 0.755 rs12562761 chr1:67396739 C/T cg02640540 chr1:67518911 SLC35D1 0.41 6.49 0.33 2.94e-10 Lymphocyte percentage of white cells; LIHC cis rs6952808 0.594 rs3778969 chr7:2139990 A/G cg04267008 chr7:1944627 MAD1L1 0.53 8.24 0.41 3.76e-15 Bipolar disorder and schizophrenia; LIHC cis rs3823572 0.542 rs2971961 chr7:133639737 G/A cg03336402 chr7:133662267 EXOC4 0.47 5.81 0.3 1.42e-8 Intelligence (multi-trait analysis); LIHC cis rs311392 0.554 rs377045 chr8:55098409 A/C cg11783602 chr8:55087084 NA -0.3 -5.99 -0.31 5.24e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs35160687 0.509 rs35723061 chr2:86549088 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 0.36 5.77 0.3 1.8e-8 Night sleep phenotypes; LIHC cis rs11195062 0.766 rs7922679 chr10:112014428 T/G cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.83 -0.3 1.28e-8 Multiple myeloma; LIHC cis rs471756 0.523 rs575307 chr9:219774 G/A cg14500300 chr9:211689 NA 0.25 5.81 0.3 1.45e-8 Mean platelet volume; LIHC cis rs2404602 0.583 rs12907668 chr15:76589767 A/T cg22467129 chr15:76604101 ETFA -0.38 -6.38 -0.33 5.63e-10 Blood metabolite levels; LIHC cis rs9948 0.786 rs111237064 chr2:97456578 T/C cg01990225 chr2:97406019 LMAN2L -0.73 -6.29 -0.32 9.78e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs2439831 0.850 rs524417 chr15:43772374 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.64 8.93 0.43 2.72e-17 Lung cancer in ever smokers; LIHC cis rs1355223 0.902 rs286862 chr11:34718779 A/G cg11058730 chr11:34937778 PDHX;APIP 0.45 6.28 0.32 1.01e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20566420 chr12:122327043 PSMD9 0.52 7.34 0.37 1.58e-12 Pancreatic cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08134342 chr12:122239035 LOC338799 -0.39 -6.05 -0.31 3.87e-9 Cognitive function; LIHC cis rs1559088 0.948 rs3760893 chr19:33597930 C/A cg17764715 chr19:33622953 WDR88 0.45 6.51 0.33 2.64e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs10751667 1.000 rs10902246 chr11:953674 T/C cg10932868 chr11:921992 NA 0.35 6.42 0.33 4.54e-10 Alzheimer's disease (late onset); LIHC cis rs9790314 0.846 rs4856738 chr3:160986637 C/G cg03342759 chr3:160939853 NMD3 -0.76 -11.11 -0.51 1.1e-24 Morning vs. evening chronotype; LIHC cis rs2361718 0.900 rs8081698 chr17:78104212 G/A cg09238746 chr17:78121135 EIF4A3 -0.48 -7.2 -0.36 3.8e-12 Yeast infection; LIHC cis rs28595532 0.748 rs72670249 chr4:119336823 G/T cg21605333 chr4:119757512 SEC24D 1.08 8.7 0.43 1.4e-16 Cannabis dependence symptom count; LIHC cis rs722599 0.715 rs2080086 chr14:75338408 G/A cg08847533 chr14:75593920 NEK9 -0.51 -7.94 -0.39 2.93e-14 IgG glycosylation; LIHC cis rs9354352 0.967 rs9354351 chr6:66696271 G/A cg07460842 chr6:66804631 NA 0.58 9.28 0.45 1.95e-18 Initial pursuit acceleration in psychotic disorders; LIHC cis rs6448317 0.520 rs13116411 chr4:24928949 G/A cg21108841 chr4:24914750 CCDC149 -0.49 -6.57 -0.33 1.82e-10 Heschl's gyrus morphology; LIHC cis rs1580019 0.587 rs34488151 chr7:32548146 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.13 25.87 0.81 1.63e-82 Cognitive ability; LIHC cis rs7208859 0.623 rs73263788 chr17:29216490 T/C cg14067834 chr17:29058358 SUZ12P 0.66 6.55 0.33 2.18e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs910316 1.000 rs8003506 chr14:75586288 A/C cg11812906 chr14:75593930 NEK9 -0.67 -12.39 -0.56 2.33e-29 Height; LIHC trans rs35110281 0.712 rs8133523 chr21:45062403 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.22 0.32 1.49e-9 Mean corpuscular volume; LIHC trans rs561341 1.000 rs7214017 chr17:30332220 T/C cg20587970 chr11:113659929 NA -1.23 -10.79 -0.5 1.51e-23 Hip circumference adjusted for BMI; LIHC cis rs9549367 0.737 rs9549712 chr13:113902355 G/A cg18105134 chr13:113819100 PROZ -0.68 -11.64 -0.53 1.29e-26 Platelet distribution width; LIHC cis rs611744 0.503 rs13282220 chr8:109263043 T/C cg18478394 chr8:109455254 TTC35 0.36 6.02 0.31 4.56e-9 Dupuytren's disease; LIHC trans rs2727020 0.521 rs7126835 chr11:49594658 T/C cg18944383 chr4:111397179 ENPEP 0.35 8.07 0.4 1.23e-14 Coronary artery disease; LIHC cis rs11888559 0.655 rs9288334 chr2:204022020 G/A cg24605529 chr2:203879461 NBEAL1 0.78 5.9 0.3 8.76e-9 Height; LIHC cis rs6456156 0.565 rs6456153 chr6:167472167 T/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.69 -0.43 1.56e-16 Primary biliary cholangitis; LIHC cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg22508957 chr16:3507546 NAT15 0.45 8.57 0.42 3.58e-16 Tuberculosis; LIHC cis rs8180040 0.726 rs2385867 chr3:47059323 C/T cg16586182 chr3:47516702 SCAP -0.5 -9.28 -0.45 2e-18 Colorectal cancer; LIHC cis rs11122272 0.735 rs2486743 chr1:231506928 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.57 -0.5 8.95e-23 Hemoglobin concentration; LIHC cis rs2274273 0.744 rs8011808 chr14:55823344 A/T cg04306507 chr14:55594613 LGALS3 0.32 5.95 0.31 6.71e-9 Protein biomarker; LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg09455208 chr3:40491958 NA 0.42 8.51 0.42 5.4e-16 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11013164 chr5:43483764 C5orf28 -0.44 -6.19 -0.32 1.69e-9 Pancreatic cancer; LIHC cis rs2073300 1.000 rs6137971 chr20:23456429 G/T cg16736954 chr20:23401023 NAPB 0.53 5.85 0.3 1.16e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4237845 0.537 rs7969844 chr12:58278271 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.58 8.08 0.4 1.11e-14 Intelligence (multi-trait analysis); LIHC cis rs11971779 0.638 rs77668044 chr7:139111085 T/A cg07862535 chr7:139043722 LUC7L2 0.68 10.33 0.49 5.88e-22 Diisocyanate-induced asthma; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg23051664 chr8:23020966 TNFRSF10D -0.49 -6.06 -0.31 3.59e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7772486 0.790 rs2256998 chr6:146207657 A/C cg05347473 chr6:146136440 FBXO30 0.37 5.94 0.31 7.11e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 12.06 0.55 3.86e-28 Height; LIHC cis rs2404602 0.583 rs12898415 chr15:76574232 C/T cg23625390 chr15:77176239 SCAPER 0.34 5.81 0.3 1.4e-8 Blood metabolite levels; LIHC cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg10802521 chr3:52805072 NEK4 0.44 7.61 0.38 2.7e-13 Bipolar disorder; LIHC cis rs9905704 0.647 rs11079367 chr17:57009024 A/G cg12560992 chr17:57184187 TRIM37 0.68 10.02 0.48 7e-21 Testicular germ cell tumor; LIHC cis rs11792861 0.962 rs72607161 chr9:111792640 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.62 0.42 2.56e-16 Menarche (age at onset); LIHC cis rs6754311 0.731 rs7569057 chr2:136583958 A/C cg07169764 chr2:136633963 MCM6 0.68 10.24 0.48 1.22e-21 Mosquito bite size; LIHC trans rs7618501 0.602 rs9311446 chr3:50092226 G/A cg21659725 chr3:3221576 CRBN -0.69 -11.23 -0.52 3.87e-25 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.620 rs9858443 chr3:47086048 G/A cg16586182 chr3:47516702 SCAP -0.48 -8.65 -0.42 2.1e-16 Colorectal cancer; LIHC cis rs4853012 0.838 rs72911122 chr2:74344119 C/G cg05890377 chr2:74357713 NA 0.63 12.81 0.57 5.75e-31 Gestational age at birth (maternal effect); LIHC cis rs748404 0.697 rs504417 chr15:43554226 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.47 8.03 0.4 1.64e-14 Lung cancer; LIHC trans rs4942242 0.663 rs34978818 chr13:44214096 T/C cg19169023 chr15:41853346 TYRO3 -0.51 -7.17 -0.36 4.61e-12 Response to tocilizumab in rheumatoid arthritis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22650146 chr1:221915355 DUSP10 0.47 6.51 0.33 2.65e-10 Pancreatic cancer; LIHC cis rs6582630 0.638 rs35864536 chr12:38472255 T/A cg26384229 chr12:38710491 ALG10B -0.46 -6.01 -0.31 4.81e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7927592 0.913 rs948316 chr11:68309670 G/T cg01657329 chr11:68192670 LRP5 -0.46 -6.06 -0.31 3.69e-9 Total body bone mineral density; LIHC cis rs6582630 0.519 rs11182457 chr12:38538331 G/A cg13010199 chr12:38710504 ALG10B 0.57 6.82 0.35 4.27e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs2404602 0.655 rs8028294 chr15:77084877 T/C cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.96e-38 Blood metabolite levels; LIHC cis rs4423214 0.569 rs12806918 chr11:71119018 G/T cg05163923 chr11:71159392 DHCR7 0.74 11.39 0.52 1.05e-25 Vitamin D levels; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs561341 0.843 rs879944 chr17:30242803 A/G cg13647721 chr17:30228624 UTP6 0.71 7.26 0.37 2.71e-12 Hip circumference adjusted for BMI; LIHC cis rs8180040 0.934 rs12630641 chr3:47534836 G/T cg16586182 chr3:47516702 SCAP -0.58 -11.08 -0.51 1.43e-24 Colorectal cancer; LIHC cis rs10911363 0.592 rs2702205 chr1:183457198 A/G cg09173681 chr1:183549694 NCF2 0.54 9.51 0.46 3.46e-19 Systemic lupus erythematosus; LIHC cis rs67311347 0.524 rs11129869 chr3:40259738 G/A cg00656387 chr3:40428638 ENTPD3 0.42 6.59 0.34 1.67e-10 Renal cell carcinoma; LIHC cis rs7552404 0.924 rs7546641 chr1:76158035 T/C cg10523679 chr1:76189770 ACADM 0.67 9.95 0.47 1.22e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1355223 0.934 rs5010670 chr11:34766649 A/C cg11058730 chr11:34937778 PDHX;APIP -0.49 -6.55 -0.33 2.1e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11958404 0.932 rs6894528 chr5:157434788 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs4819052 0.851 rs28442024 chr21:46674475 C/A cg11663144 chr21:46675770 NA -0.32 -5.94 -0.31 6.96e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12908161 1.000 rs35808647 chr15:85377441 G/A cg17507749 chr15:85114479 UBE2QP1 0.59 6.47 0.33 3.45e-10 Schizophrenia; LIHC cis rs2204008 0.840 rs7136347 chr12:38453531 G/A cg13010199 chr12:38710504 ALG10B 0.53 6.2 0.32 1.61e-9 Bladder cancer; LIHC cis rs920590 0.758 rs1907799 chr8:19664668 A/G cg01411142 chr8:19674711 INTS10 -0.48 -7.51 -0.38 5.35e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs6089584 0.528 rs4925335 chr20:60627034 G/A cg06108461 chr20:60628389 TAF4 -0.65 -8.98 -0.44 1.87e-17 Body mass index; LIHC cis rs763121 0.962 rs6001159 chr22:38966487 A/G cg06544989 chr22:39130855 UNC84B 0.35 5.77 0.3 1.78e-8 Menopause (age at onset); LIHC cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 0.43 6.1 0.31 2.86e-9 Colorectal cancer; LIHC cis rs3806843 1.000 rs7701755 chr5:140182101 G/T cg19875535 chr5:140030758 IK 0.36 5.89 0.3 9.03e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2439831 0.850 rs3816792 chr15:44116986 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.51 -6.52 -0.33 2.57e-10 Lung cancer in ever smokers; LIHC cis rs7666738 0.830 rs4699577 chr4:98846513 G/A cg05340658 chr4:99064831 C4orf37 0.65 11.84 0.54 2.48e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7772486 0.875 rs2207785 chr6:146332784 T/G cg23711669 chr6:146136114 FBXO30 0.66 11.67 0.53 1.02e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9381040 0.655 rs7738684 chr6:41038552 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.43 -6.69 -0.34 8.96e-11 Alzheimer's disease (late onset); LIHC cis rs6882046 0.513 rs676096 chr5:88035887 C/T cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs910316 0.737 rs91144 chr14:75449517 G/A cg08847533 chr14:75593920 NEK9 -0.87 -17.94 -0.7 3.3e-51 Height; LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg07133347 chr1:107600762 PRMT6 -0.45 -6.73 -0.34 7.25e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6570726 0.791 rs418701 chr6:145889992 C/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.45 -0.33 3.8e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11122272 0.735 rs2486743 chr1:231506928 C/G cg06096015 chr1:231504339 EGLN1 0.5 9.46 0.46 5.31e-19 Hemoglobin concentration; LIHC cis rs10078 0.571 rs2241597 chr5:480509 A/G cg07599136 chr5:415885 AHRR 0.76 12.65 0.56 2.34e-30 Fat distribution (HIV); LIHC cis rs6831352 0.918 rs13107558 chr4:100050200 C/A cg12011299 chr4:100065546 ADH4 -0.56 -9.53 -0.46 2.99e-19 Alcohol dependence; LIHC cis rs3008870 0.755 rs2815368 chr1:67500778 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.66 11.31 0.52 2.03e-25 Lymphocyte percentage of white cells; LIHC cis rs6988636 1.000 rs13261066 chr8:124190276 G/A cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs3768617 0.510 rs723014 chr1:183076287 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 5.1e-23 Fuchs's corneal dystrophy; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.48 -5.98 -0.31 5.47e-9 Diastolic blood pressure; LIHC cis rs7617773 0.539 rs11130165 chr3:48384721 G/T cg11946769 chr3:48343235 NME6 0.56 6.8 0.35 4.63e-11 Coronary artery disease; LIHC cis rs7412746 0.658 rs6656535 chr1:150940357 G/T cg17724175 chr1:150552817 MCL1 0.41 8.05 0.4 1.34e-14 Melanoma; LIHC cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg27297192 chr10:134578999 INPP5A 0.54 7.75 0.39 1.07e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.54 7.58 0.38 3.18e-13 Lymphocyte counts; LIHC cis rs8062405 0.965 rs7359397 chr16:28885659 C/T cg16576597 chr16:28551801 NUPR1 0.37 5.83 0.3 1.26e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs17685 0.753 rs12531559 chr7:75631697 C/T cg16684958 chr7:75615977 POR -0.5 -8.44 -0.42 9.36e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12467847 1.000 rs4387792 chr2:113691288 T/C cg12858261 chr2:113808755 IL1F8 -0.35 -5.88 -0.3 9.83e-9 Response to amphetamines; LIHC cis rs875971 1.000 rs3981131 chr7:65951677 A/G cg18252515 chr7:66147081 NA -0.43 -5.93 -0.31 7.31e-9 Aortic root size; LIHC cis rs7772486 0.754 rs9497419 chr6:146142609 T/C cg13319975 chr6:146136371 FBXO30 -0.35 -5.93 -0.31 7.4e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2122469 0.655 rs17603982 chr8:20581401 G/C cg20211604 chr17:11632341 DNAH9 0.52 6.43 0.33 4.34e-10 Serum tamsulosin hydrochloride concentration; LIHC cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg08280861 chr8:58055591 NA 0.55 6.28 0.32 1.05e-9 Developmental language disorder (linguistic errors); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19759883 chr12:14956454 WBP11;C12orf60 0.35 6.28 0.32 1.01e-9 Calcium levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12032228 chr14:64854572 MTHFD1 -0.4 -6.06 -0.31 3.62e-9 Cognitive function; LIHC cis rs11971779 0.715 rs7787398 chr7:139061846 A/G cg07862535 chr7:139043722 LUC7L2 0.63 11.1 0.51 1.2e-24 Diisocyanate-induced asthma; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg25468541 chr7:5014008 RNF216L 0.53 6.37 0.33 6.22e-10 Hepatitis; LIHC cis rs36051895 0.632 rs12336875 chr9:5138404 C/A cg02405213 chr9:5042618 JAK2 -0.68 -11.87 -0.54 1.96e-27 Pediatric autoimmune diseases; LIHC cis rs477692 0.673 rs10829600 chr10:131322051 G/C cg05714579 chr10:131428358 MGMT 0.41 6.63 0.34 1.3100000000000001e-10 Response to temozolomide; LIHC cis rs1816752 0.905 rs7991450 chr13:25000036 T/G cg22771759 chr13:24902376 NA 0.32 6.66 0.34 1.12e-10 Obesity-related traits; LIHC cis rs5769765 0.955 rs2319465 chr22:50265784 A/C cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs8180040 0.620 rs56217494 chr3:47048452 T/G cg16586182 chr3:47516702 SCAP 0.48 8.68 0.42 1.62e-16 Colorectal cancer; LIHC cis rs7208859 0.623 rs8068645 chr17:29104342 T/A cg13385521 chr17:29058706 SUZ12P 0.83 8.19 0.41 5.17e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9911578 1.000 rs9915935 chr17:56843048 A/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.64 -0.42 2.19e-16 Intelligence (multi-trait analysis); LIHC cis rs918629 0.567 rs6885567 chr5:95258754 T/G cg10483112 chr5:95245456 ELL2 -0.38 -7.17 -0.36 4.76e-12 IgG glycosylation; LIHC cis rs10832963 0.686 rs11024743 chr11:18653712 A/G cg09201001 chr11:18656081 SPTY2D1 0.93 17.06 0.68 1.15e-47 Breast cancer; LIHC cis rs1568889 1.000 rs34667360 chr11:28055650 T/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.48 6.5 0.33 2.91e-10 Bipolar disorder; LIHC cis rs4820539 0.966 rs2157709 chr22:23457420 T/C cg21100191 chr22:23484243 RTDR1 0.85 14.99 0.63 2.13e-39 Bone mineral density; LIHC cis rs763014 0.932 rs2269560 chr16:682442 A/C cg27189623 chr16:705930 WDR90 0.42 6.96 0.35 1.74e-11 Height; LIHC cis rs2404602 0.692 rs36070630 chr15:76949259 T/C cg03037974 chr15:76606532 NA 0.74 14.31 0.61 1e-36 Blood metabolite levels; LIHC cis rs4671400 0.602 rs2694623 chr2:61553466 C/T cg14146966 chr2:61757674 XPO1 -0.38 -5.94 -0.31 7.06e-9 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg25894440 chr7:65020034 NA -0.55 -6.33 -0.32 7.79e-10 Diabetic kidney disease; LIHC cis rs4332037 0.539 rs56305291 chr7:2048706 A/G cg23422044 chr7:1970798 MAD1L1 -0.52 -6.1 -0.31 2.87e-9 Bipolar disorder; LIHC cis rs9814567 1.000 rs7611828 chr3:134250325 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4920343 0.645 rs851115 chr1:19070229 T/A cg19637330 chr1:19110922 NA 0.32 5.89 0.3 9.24e-9 Knee osteoarthritis; LIHC cis rs4474465 1.000 rs11237508 chr11:78173297 C/T cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs13223928 0.511 rs11773338 chr7:3144508 T/C cg19214707 chr7:3157722 NA -0.4 -7.65 -0.38 2.09e-13 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs3106136 0.527 rs4693376 chr4:95157240 A/G cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.13 -0.44 6.09e-18 Capecitabine sensitivity; LIHC cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg25072359 chr17:41440525 NA 0.37 5.91 0.3 8.06e-9 Menopause (age at onset); LIHC cis rs9473924 0.505 rs9296644 chr6:50828247 G/A cg14470998 chr6:50812995 TFAP2B 0.86 9.78 0.47 4.3e-20 Body mass index; LIHC cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 12.63 0.56 2.73e-30 Alzheimer's disease; LIHC trans rs35740288 0.621 rs12916001 chr15:86245269 G/A cg20536716 chr7:119913368 KCND2 0.4 6.17 0.32 1.9e-9 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg04013166 chr16:89971882 TCF25 0.61 7.97 0.4 2.38e-14 Skin colour saturation; LIHC cis rs11190604 1.000 rs11190592 chr10:102291059 T/C cg07080220 chr10:102295463 HIF1AN 0.57 8.09 0.4 1.05e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6546550 0.901 rs10205487 chr2:70151471 C/T cg02498382 chr2:70120550 SNRNP27 0.45 7.77 0.39 9.55e-14 Prevalent atrial fibrillation; LIHC trans rs13381277 1.000 rs9959410 chr18:74329953 G/A cg17352830 chr21:37617589 DOPEY2 -0.55 -6.4 -0.33 5e-10 Dental caries; LIHC cis rs9611565 0.644 rs2413652 chr22:42097238 C/T cg06634786 chr22:41940651 POLR3H 0.56 6.16 0.32 2e-9 Vitiligo; LIHC trans rs11098499 0.644 rs7693919 chr4:120540571 G/A cg25214090 chr10:38739885 LOC399744 0.5 8.15 0.4 7.13e-15 Corneal astigmatism; LIHC cis rs12477438 0.798 rs12473029 chr2:99637961 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.14 -17.23 -0.68 2.46e-48 Chronic sinus infection; LIHC cis rs7238033 0.624 rs7233769 chr18:43306681 A/G cg20610511 chr18:43302872 SLC14A1 0.4 6.59 0.34 1.69e-10 Bladder cancer; LIHC cis rs12477438 0.765 rs13390672 chr2:99589829 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.55 -0.38 3.87e-13 Chronic sinus infection; LIHC cis rs798554 0.671 rs1182195 chr7:2868730 A/G cg13628971 chr7:2884303 GNA12 0.39 5.79 0.3 1.63e-8 Height; LIHC trans rs66573146 0.656 rs56094305 chr4:6956086 C/T cg07817883 chr1:32538562 TMEM39B 1.02 9.01 0.44 1.54e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs780096 0.565 rs11681351 chr2:27743423 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.11 -0.31 2.73e-9 Total body bone mineral density; LIHC cis rs8103278 0.860 rs11669073 chr19:46324880 C/T cg11657440 chr19:46296263 DMWD -0.53 -8.19 -0.4 5.43e-15 Coronary artery disease; LIHC cis rs425535 0.619 rs4694655 chr4:74806082 C/T cg02530824 chr4:74847766 PF4 -0.39 -6.02 -0.31 4.48e-9 Blood protein levels; LIHC cis rs801193 0.967 rs2707841 chr7:66157020 A/G cg18876405 chr7:65276391 NA 0.43 7.55 0.38 3.92e-13 Aortic root size; LIHC cis rs3806843 1.000 rs2098058 chr5:140157427 A/C cg26395211 chr5:140044315 WDR55 0.42 6.23 0.32 1.35e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7843479 0.965 rs11135742 chr8:21802910 A/T cg17168535 chr8:21777572 XPO7 0.39 6.31 0.32 8.56e-10 Mean corpuscular volume; LIHC cis rs79387448 0.655 rs77763678 chr2:102916749 G/A cg09003973 chr2:102972529 NA 1.2 9.65 0.46 1.2e-19 Gut microbiota (bacterial taxa); LIHC cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg12463550 chr7:65579703 CRCP 0.67 7.06 0.36 9.42e-12 Diabetic kidney disease; LIHC cis rs9811920 0.609 rs793501 chr3:99591638 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs727563 0.555 rs5751136 chr22:42075581 T/A cg06634786 chr22:41940651 POLR3H 0.62 6.62 0.34 1.38e-10 Crohn's disease;Inflammatory bowel disease; LIHC cis rs546131 0.642 rs2915186 chr11:34851183 C/T cg06937548 chr11:34938143 PDHX;APIP 0.56 7.39 0.37 1.14e-12 Lung disease severity in cystic fibrosis; LIHC cis rs35306767 0.761 rs11253557 chr10:1043667 C/T cg26597838 chr10:835615 NA 0.9 8.74 0.43 1.04e-16 Eosinophil percentage of granulocytes; LIHC cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg05564831 chr3:52568323 NT5DC2 0.36 5.9 0.3 8.88e-9 Bipolar disorder; LIHC cis rs4969178 0.965 rs11653305 chr17:76386918 T/C cg20026190 chr17:76395443 PGS1 0.46 7.21 0.36 3.52e-12 HDL cholesterol levels; LIHC cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg11062466 chr8:58055876 NA -0.45 -6.22 -0.32 1.41e-9 Developmental language disorder (linguistic errors); LIHC cis rs6120849 0.754 rs6120788 chr20:33583716 C/T cg06115741 chr20:33292138 TP53INP2 0.5 5.74 0.3 2.14e-8 Protein C levels; LIHC cis rs6952808 0.760 rs11764960 chr7:1950532 G/A cg20295408 chr7:1910781 MAD1L1 -0.52 -7.47 -0.37 6.75e-13 Bipolar disorder and schizophrenia; LIHC cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg11062466 chr8:58055876 NA 0.4 5.84 0.3 1.21e-8 Developmental language disorder (linguistic errors); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg07573366 chr7:32802765 NA 0.31 7.47 0.37 6.95e-13 Bilirubin levels; LIHC cis rs66569888 0.632 rs6728600 chr2:106898653 G/T cg00318621 chr2:106887213 NA -0.58 -5.78 -0.3 1.73e-8 Facial morphology (factor 23); LIHC cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg14004847 chr7:1930337 MAD1L1 -0.43 -6.23 -0.32 1.34e-9 Bipolar disorder and schizophrenia; LIHC cis rs1419980 0.673 rs12366473 chr12:7728270 G/C cg14906510 chr12:7781169 NA 0.48 7.3 0.37 1.97e-12 HDL cholesterol levels; LIHC cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg07636037 chr3:49044803 WDR6 0.76 12.72 0.57 1.34e-30 Menarche (age at onset); LIHC cis rs3849570 0.643 rs10779986 chr3:81970818 C/G cg07356753 chr3:81810745 GBE1 0.53 8.29 0.41 2.56e-15 Waist circumference;Body mass index; LIHC trans rs4332037 0.901 rs11767040 chr7:1945468 C/T cg11693508 chr17:37793320 STARD3 0.74 7.62 0.38 2.51e-13 Bipolar disorder; LIHC cis rs7523273 0.606 rs2724388 chr1:207933577 T/G cg22525895 chr1:207977042 MIR29B2 0.64 10.3 0.49 7.46e-22 Schizophrenia; LIHC cis rs17125944 0.505 rs75838476 chr14:53242362 G/A cg13660082 chr14:53194042 PSMC6 -0.46 -7.6 -0.38 2.85e-13 Alzheimer's disease (late onset); LIHC trans rs1005277 0.505 rs10827836 chr10:38215441 A/G cg27523141 chr10:43048294 ZNF37B -0.39 -6.82 -0.35 4.18e-11 Extrinsic epigenetic age acceleration; LIHC cis rs2806561 0.695 rs66592286 chr1:23333649 G/C cg12483005 chr1:23474871 LUZP1 0.45 6.88 0.35 2.86e-11 Height; LIHC cis rs5769765 0.865 rs4824108 chr22:50271428 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC trans rs7618501 0.602 rs2301166 chr3:50148305 C/G cg21659725 chr3:3221576 CRBN -0.68 -10.84 -0.51 9.9899999999999993e-24 Intelligence (multi-trait analysis); LIHC cis rs1355223 0.902 rs7121272 chr11:34752562 T/G cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.56 -0.33 2e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2180341 0.782 rs6912750 chr6:127723081 A/T cg24812749 chr6:127587940 RNF146 0.79 12.47 0.56 1.1e-29 Breast cancer; LIHC cis rs2242116 0.932 rs1531137 chr3:46943028 T/C cg02527881 chr3:46936655 PTH1R -0.54 -11.92 -0.54 1.2e-27 Birth weight; LIHC cis rs801193 0.967 rs2420827 chr7:66147101 G/A cg18252515 chr7:66147081 NA 0.43 5.73 0.3 2.2e-8 Aortic root size; LIHC cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg06634786 chr22:41940651 POLR3H 0.79 8.82 0.43 6.02e-17 Vitiligo; LIHC cis rs10751667 0.600 rs11246377 chr11:999796 G/T ch.11.42038R chr11:967971 AP2A2 0.6 11.25 0.52 3.48e-25 Alzheimer's disease (late onset); LIHC cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg16049864 chr8:95962084 TP53INP1 -0.63 -11.79 -0.54 3.69e-27 Type 2 diabetes; LIHC cis rs9303401 0.659 rs34351230 chr17:56782555 C/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs2629540 0.731 rs11245341 chr10:126408777 G/C cg20435097 chr10:126320824 FAM53B -0.41 -6.0 -0.31 4.96e-9 Cocaine dependence; LIHC cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg11987759 chr7:65425863 GUSB 0.38 6.14 0.31 2.32e-9 Aortic root size; LIHC cis rs9733 0.519 rs7521898 chr1:150707596 G/A cg17724175 chr1:150552817 MCL1 0.49 9.89 0.47 1.92e-20 Tonsillectomy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21509040 chr20:61814830 NA 0.37 6.13 0.31 2.36e-9 Cognitive function; LIHC cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg00684032 chr4:1343700 KIAA1530 -0.5 -7.35 -0.37 1.44e-12 Obesity-related traits; LIHC cis rs1198430 0.639 rs1767147 chr1:23770516 A/G cg19827787 chr1:23763612 ASAP3 0.28 6.09 0.31 2.99e-9 Total cholesterol levels; LIHC cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg09069446 chr16:4462122 CORO7 -0.35 -5.71 -0.3 2.45e-8 Schizophrenia; LIHC cis rs2836950 0.502 rs2150411 chr21:40574552 G/T cg06238570 chr21:40685208 BRWD1 -0.44 -7.17 -0.36 4.57e-12 Menarche (age at onset); LIHC cis rs2070488 0.965 rs1984312 chr3:38538466 G/T cg24069376 chr3:38537580 EXOG -0.4 -7.32 -0.37 1.78e-12 Electrocardiographic conduction measures; LIHC cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.64e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.71 0.38 1.35e-13 Prudent dietary pattern; LIHC cis rs2404602 0.967 rs2083762 chr15:76907376 T/C cg23625390 chr15:77176239 SCAPER 0.39 6.46 0.33 3.5e-10 Blood metabolite levels; LIHC cis rs8044995 0.636 rs117761434 chr16:68254196 G/A cg09835421 chr16:68378352 PRMT7 -0.52 -5.98 -0.31 5.58e-9 Schizophrenia; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg26354017 chr1:205819088 PM20D1 0.75 11.07 0.51 1.51e-24 Menarche (age at onset); LIHC cis rs2404602 0.660 rs11852777 chr15:76929792 A/G cg23625390 chr15:77176239 SCAPER -0.53 -8.69 -0.43 1.55e-16 Blood metabolite levels; LIHC cis rs35110281 0.744 rs162373 chr21:44927107 C/A cg21573476 chr21:45109991 RRP1B 0.49 8.95 0.44 2.37e-17 Mean corpuscular volume; LIHC cis rs7191439 0.858 rs7205626 chr16:88780472 T/C cg02389323 chr16:88786976 FAM38A 0.75 6.93 0.35 2.08e-11 Plateletcrit; LIHC cis rs11112613 0.713 rs17041546 chr12:105950801 G/T cg03607813 chr12:105948248 NA -0.63 -12.77 -0.57 8.58e-31 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs4950322 0.553 rs12093870 chr1:146852536 A/C cg25205988 chr1:146714368 CHD1L -0.41 -5.95 -0.31 6.75e-9 Protein quantitative trait loci; LIHC cis rs7534824 0.625 rs61780286 chr1:101359898 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 6.97 0.35 1.6e-11 Refractive astigmatism; LIHC cis rs6977660 0.941 rs5017192 chr7:19820114 C/T cg07541023 chr7:19748670 TWISTNB 0.36 5.74 0.3 2.1e-8 Thyroid stimulating hormone; LIHC cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg11663144 chr21:46675770 NA -0.34 -6.32 -0.32 7.99e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1003719 0.788 rs1155787 chr21:38448069 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 7e-29 Eye color traits; LIHC cis rs6977660 0.943 rs12668201 chr7:19831610 A/C cg07541023 chr7:19748670 TWISTNB -0.38 -6.05 -0.31 3.77e-9 Thyroid stimulating hormone; LIHC cis rs2180341 0.814 rs9385424 chr6:127726796 A/G cg24812749 chr6:127587940 RNF146 0.8 12.66 0.56 2.11e-30 Breast cancer; LIHC cis rs909002 0.772 rs10798876 chr1:32074514 C/G cg13919466 chr1:32135498 COL16A1 -0.34 -6.33 -0.32 7.68e-10 Intelligence (multi-trait analysis); LIHC cis rs2236918 1.000 rs1776133 chr1:242025098 C/T cg17736920 chr1:242011382 EXO1 0.56 8.6 0.42 2.91e-16 Menopause (age at onset); LIHC cis rs10508774 0.810 rs1402185 chr10:32778152 G/A cg01819863 chr10:32635814 EPC1 0.61 5.8 0.3 1.49e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2257205 0.667 rs7221142 chr17:56758786 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -6.47 -0.33 3.49e-10 Pancreatic cancer; LIHC cis rs7412746 0.658 rs11204750 chr1:150939744 C/A cg15448220 chr1:150897856 SETDB1 0.43 6.83 0.35 3.86e-11 Melanoma; LIHC cis rs7267979 1.000 rs4815411 chr20:25350223 A/G cg24626310 chr20:25276739 ABHD12;PYGB -0.45 -6.69 -0.34 9.34e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs826838 1.000 rs11183214 chr12:38692938 C/T cg13010199 chr12:38710504 ALG10B 0.64 7.9 0.39 3.86e-14 Heart rate; LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.61 -0.34 1.49e-10 Total body bone mineral density; LIHC trans rs561341 1.000 rs68140514 chr17:30335781 T/C cg20587970 chr11:113659929 NA -1.28 -11.31 -0.52 2.13e-25 Hip circumference adjusted for BMI; LIHC cis rs244293 0.965 rs2214980 chr17:53207061 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.45 -0.37 7.67e-13 Menarche (age at onset); LIHC cis rs9612 0.718 rs346536 chr19:44251470 A/T cg08581076 chr19:44259116 C19orf61 0.59 7.77 0.39 9.53e-14 Exhaled nitric oxide output; LIHC cis rs2629540 0.889 rs10901808 chr10:126399159 A/C cg20435097 chr10:126320824 FAM53B -0.41 -5.98 -0.31 5.77e-9 Cocaine dependence; LIHC cis rs7927592 0.513 rs901823 chr11:68205578 T/C cg16797656 chr11:68205561 LRP5 0.61 11.02 0.51 2.19e-24 Total body bone mineral density; LIHC cis rs274567 0.599 rs11242110 chr5:131743777 A/C cg07395648 chr5:131743802 NA 0.4 8.56 0.42 3.81e-16 Blood metabolite levels; LIHC cis rs4975616 0.710 rs27996 chr5:1345474 A/G cg07493874 chr5:1342172 CLPTM1L -0.63 -9.94 -0.47 1.23e-20 Lung cancer; LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6597326 chr6:8482019 A/C cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs11112613 1.000 rs11112613 chr12:106003786 A/G cg03607813 chr12:105948248 NA 0.58 9.22 0.45 3.14e-18 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs34779708 0.966 rs4934737 chr10:35512799 T/C cg04310649 chr10:35416472 CREM -0.43 -5.75 -0.3 1.97e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9325144 0.560 rs10785586 chr12:38676197 G/A cg26384229 chr12:38710491 ALG10B -0.6 -8.19 -0.4 5.22e-15 Morning vs. evening chronotype; LIHC cis rs798554 0.704 rs798531 chr7:2770067 G/C cg19717773 chr7:2847554 GNA12 -0.39 -6.9 -0.35 2.52e-11 Height; LIHC cis rs7927592 0.673 rs498782 chr11:68275851 A/G cg01657329 chr11:68192670 LRP5 -0.49 -7.29 -0.37 2.18e-12 Total body bone mineral density; LIHC cis rs4819052 0.851 rs28442024 chr21:46674475 C/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.5 0.38 5.48e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs921968 1.000 rs56191141 chr2:219272145 A/G cg02176678 chr2:219576539 TTLL4 -0.4 -5.95 -0.31 6.78e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs6840360 0.571 rs4696276 chr4:152532682 G/A cg22705602 chr4:152727874 NA -0.33 -6.37 -0.33 5.98e-10 Intelligence (multi-trait analysis); LIHC cis rs4319547 0.695 rs4758645 chr12:122946487 G/A cg23029597 chr12:123009494 RSRC2 -0.49 -6.96 -0.35 1.75e-11 Body mass index; LIHC cis rs7659604 0.605 rs67772833 chr4:122723106 G/A cg20573242 chr4:122745356 CCNA2 0.38 6.12 0.31 2.62e-9 Type 2 diabetes; LIHC cis rs2370759 1.000 rs11599522 chr10:32568434 G/C cg18270830 chr10:32634957 EPC1 0.54 6.61 0.34 1.46e-10 Sexual dysfunction (female); LIHC trans rs75804782 0.641 rs72987328 chr2:239360097 C/T cg01134436 chr17:81009848 B3GNTL1 0.81 6.82 0.35 4.06e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs7659604 0.582 rs3217780 chr4:122737278 T/C cg20573242 chr4:122745356 CCNA2 0.52 7.62 0.38 2.5e-13 Type 2 diabetes; LIHC cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg11764359 chr7:65958608 NA -0.58 -6.08 -0.31 3.14e-9 Diabetic kidney disease; LIHC cis rs11676348 0.846 rs11677534 chr2:219007060 T/C cg00012203 chr2:219082015 ARPC2 -0.55 -7.76 -0.39 9.71e-14 Ulcerative colitis; LIHC cis rs10463316 0.894 rs10062856 chr5:150768196 C/G cg03212797 chr5:150827313 SLC36A1 -0.44 -6.71 -0.34 7.92e-11 Metabolite levels (Pyroglutamine); LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg00091569 chr3:40428383 ENTPD3 0.39 6.53 0.33 2.43e-10 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00142735 chr15:64454827 PPIB 0.44 6.34 0.32 7.16e-10 Pancreatic cancer; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg20971159 chr15:74703254 SEMA7A 0.39 6.32 0.32 8.22e-10 Alopecia areata; LIHC cis rs6964587 1.000 rs2282968 chr7:91580287 A/C cg17063962 chr7:91808500 NA -1.03 -19.89 -0.73 4.87e-59 Breast cancer; LIHC cis rs4450131 0.522 rs11245323 chr10:126344624 C/T cg20435097 chr10:126320824 FAM53B 0.67 12.2 0.55 1.12e-28 White blood cell count (basophil); LIHC cis rs6690583 0.623 rs7540706 chr1:85534645 A/G cg22153463 chr1:85462885 MCOLN2 -0.54 -6.89 -0.35 2.72e-11 Serum sulfate level; LIHC cis rs919433 0.929 rs1366836 chr2:198172148 T/G cg10820045 chr2:198174542 NA -0.6 -10.31 -0.49 6.83e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs7618501 0.633 rs4688758 chr3:50028385 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.48 0.46 4.54e-19 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.773 rs2137990 chr17:41317896 T/A cg23758822 chr17:41437982 NA -0.92 -17.0 -0.68 2.02e-47 Menopause (age at onset); LIHC cis rs9325144 0.555 rs4882358 chr12:38726640 A/G cg26384229 chr12:38710491 ALG10B 0.59 8.28 0.41 2.77e-15 Morning vs. evening chronotype; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02793854 chr16:67867809 CENPT -0.53 -6.11 -0.31 2.72e-9 Systolic blood pressure; LIHC trans rs5756813 0.782 rs3171656 chr22:38172213 G/A cg19894588 chr14:64061835 NA -0.66 -9.1 -0.44 7.89e-18 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7264396 0.623 rs2425127 chr20:34332037 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.57 -0.42 3.68e-16 Total cholesterol levels; LIHC cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg03806693 chr22:41940476 POLR3H -1.08 -11.42 -0.53 8.04e-26 Vitiligo; LIHC cis rs6748734 1.000 rs4675874 chr2:241819796 A/G cg04034577 chr2:241836375 C2orf54 0.38 7.48 0.37 6.45e-13 Urinary metabolites; LIHC cis rs722599 0.683 rs8011071 chr14:75286705 T/C cg08847533 chr14:75593920 NEK9 0.51 7.69 0.38 1.58e-13 IgG glycosylation; LIHC cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg18402987 chr7:1209562 NA 0.81 6.01 0.31 4.73e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs796364 0.587 rs7588746 chr2:200986345 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.48 5.83 0.3 1.27e-8 Schizophrenia; LIHC cis rs16958440 0.867 rs3809966 chr18:44677627 C/T cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs4319547 0.656 rs7975747 chr12:122816995 C/T cg23029597 chr12:123009494 RSRC2 -0.51 -7.35 -0.37 1.47e-12 Body mass index; LIHC cis rs8062405 0.755 rs1074631 chr16:28554108 A/G cg07451762 chr16:28383216 NA -0.38 -6.55 -0.33 2.16e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4407350 0.870 rs5764877 chr22:44915530 T/G cg26276947 chr22:44892394 LDOC1L 0.34 6.51 0.33 2.69e-10 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12368702 chr16:53165711 CHD9 0.48 6.73 0.34 7.31e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.33 0.32 7.63e-10 Renal cell carcinoma; LIHC cis rs7131987 0.903 rs10843373 chr12:29420608 A/T cg12903224 chr12:29470962 FAR2 -0.37 -5.94 -0.31 6.91e-9 QT interval; LIHC cis rs5995875 0.524 rs7284506 chr22:41057977 C/T cg14879645 chr22:41048474 NA 0.4 5.72 0.3 2.3e-8 Breast size; LIHC cis rs55882075 0.537 rs62406698 chr5:179110429 C/T cg14593053 chr5:179126677 CANX 0.42 7.24 0.36 3.06e-12 Monocyte percentage of white cells; LIHC cis rs11864453 0.680 rs8047377 chr16:72148339 T/C cg01557791 chr16:72042693 DHODH -0.45 -7.48 -0.38 6.25e-13 Fibrinogen levels; LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg18279126 chr7:2041391 MAD1L1 0.39 6.51 0.33 2.74e-10 Bipolar disorder and schizophrenia; LIHC cis rs116248771 0.690 rs73156492 chr3:158416799 G/C cg16708174 chr3:158430962 RARRES1 0.48 6.34 0.32 7.39e-10 diarrhoeal disease at age 2; LIHC cis rs7503807 0.935 rs9910745 chr17:78610543 C/T cg09596252 chr17:78655493 RPTOR 0.38 6.89 0.35 2.62e-11 Obesity; LIHC cis rs317689 0.690 rs595348 chr12:69638610 T/C cg20891283 chr12:69753455 YEATS4 0.48 6.72 0.34 7.41e-11 Response to diuretic therapy; LIHC cis rs748404 0.560 rs689797 chr15:43826557 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.37 6.11 0.31 2.73e-9 Lung cancer; LIHC cis rs2991971 0.869 rs2453404 chr1:46014735 A/G cg15605315 chr1:45957053 TESK2 0.45 5.89 0.3 9.42e-9 High light scatter reticulocyte count; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17370785 chr4:2252266 MXD4 0.41 6.04 0.31 4.02e-9 Longevity; LIHC trans rs2797160 0.967 rs2797159 chr6:126009557 G/A cg05039488 chr6:79577232 IRAK1BP1 0.46 6.5 0.33 2.88e-10 Endometrial cancer; LIHC cis rs1552244 0.554 rs2272122 chr3:10047975 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.54 7.49 0.38 5.81e-13 Alzheimer's disease; LIHC cis rs2073300 0.609 rs6137914 chr20:23358364 C/T cg16736954 chr20:23401023 NAPB 0.71 8.3 0.41 2.48e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10089 0.953 rs10463839 chr5:127519675 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.21 0.32 1.55e-9 Ileal carcinoids; LIHC cis rs9303401 0.625 rs66508449 chr17:56691034 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.48 0.56 1.05e-29 Cognitive test performance; LIHC cis rs12824058 0.831 rs7979497 chr12:130804706 C/T cg24229701 chr12:130821962 PIWIL1 0.42 6.12 0.31 2.57e-9 Menopause (age at onset); LIHC cis rs1580019 0.587 rs7804457 chr7:32557981 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.86 0.43 4.45e-17 Cognitive ability; LIHC cis rs796364 0.950 rs188146 chr2:200750444 C/T cg23649088 chr2:200775458 C2orf69 0.49 5.82 0.3 1.36e-8 Schizophrenia; LIHC cis rs3761847 0.593 rs1468673 chr9:123809890 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 5.71 0.3 2.42e-8 Rheumatoid arthritis; LIHC cis rs11676348 0.776 rs11690316 chr2:219017462 A/G cg00012203 chr2:219082015 ARPC2 -0.62 -8.42 -0.41 1.05e-15 Ulcerative colitis; LIHC cis rs67311347 0.713 rs73073505 chr3:40310693 C/T cg00656387 chr3:40428638 ENTPD3 0.41 6.5 0.33 2.77e-10 Renal cell carcinoma; LIHC cis rs7020830 0.861 rs2291589 chr9:37079661 T/G cg14294708 chr9:37120828 ZCCHC7 1.11 23.99 0.79 2.76e-75 Schizophrenia; LIHC cis rs7575217 0.767 rs796064 chr2:101729682 G/A cg23907051 chr2:101730305 TBC1D8 -0.28 -6.46 -0.33 3.67e-10 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; LIHC cis rs950169 0.922 rs11635505 chr15:85097034 A/C cg12863693 chr15:85201151 NMB -0.4 -5.77 -0.3 1.76e-8 Schizophrenia; LIHC cis rs10779751 0.960 rs1883965 chr1:11322156 A/G cg08854313 chr1:11322531 MTOR 0.86 12.79 0.57 6.99e-31 Body mass index; LIHC cis rs4820539 1.000 rs885964 chr22:23461003 G/C cg14186256 chr22:23484241 RTDR1 0.97 20.63 0.74 5.12e-62 Bone mineral density; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04953579 chr7:151216578 RHEB 0.48 6.61 0.34 1.45e-10 Lung function (FEV1/FVC); LIHC cis rs7618501 0.665 rs7621352 chr3:50070763 A/C cg21467203 chr3:49911342 NA 0.43 7.67 0.38 1.82e-13 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.740 rs7152196 chr14:90703900 G/T cg04374321 chr14:90722782 PSMC1 0.73 14.06 0.61 9.37e-36 Mortality in heart failure; LIHC cis rs35883536 0.588 rs10465764 chr1:101105030 A/G cg14515779 chr1:101123966 NA -0.59 -11.08 -0.51 1.33e-24 Monocyte count; LIHC cis rs473651 0.904 rs551859 chr2:239371836 T/C cg08773314 chr2:239334832 ASB1 0.31 5.79 0.3 1.63e-8 Multiple system atrophy; LIHC cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg27286337 chr10:134555280 INPP5A 0.87 13.06 0.58 6.89e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs265548 0.538 rs36688 chr19:17911212 A/C cg04517722 chr19:17905589 B3GNT3 0.46 6.93 0.35 2.16e-11 Tumor biomarkers; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg18580296 chr7:15726411 MEOX2 -0.39 -6.57 -0.33 1.89e-10 Body mass index; LIHC trans rs11098499 0.913 rs68128210 chr4:120137819 T/G cg25214090 chr10:38739885 LOC399744 0.45 7.24 0.36 2.95e-12 Corneal astigmatism; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg02782426 chr3:40428986 ENTPD3 0.33 6.1 0.31 2.87e-9 Renal cell carcinoma; LIHC cis rs950169 1.000 rs1818950 chr15:84722521 A/G cg17507749 chr15:85114479 UBE2QP1 0.75 7.6 0.38 2.9e-13 Schizophrenia; LIHC trans rs1552244 0.572 rs17032426 chr3:10167112 G/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC trans rs617791 0.530 rs10791835 chr11:65750924 C/A cg17712092 chr4:129076599 LARP1B -0.56 -6.8 -0.35 4.55e-11 Breast cancer; LIHC trans rs11098499 0.738 rs72918577 chr4:120326701 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.69 0.46 9.07e-20 Corneal astigmatism; LIHC cis rs6066825 0.644 rs6019380 chr20:47318845 A/G cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.59e-12 Colorectal cancer; LIHC cis rs780096 0.546 rs35073769 chr2:27731376 C/T cg05484376 chr2:27715224 FNDC4 0.4 6.69 0.34 9.08e-11 Total body bone mineral density; LIHC cis rs10792665 0.671 rs3862772 chr11:82671930 C/G cg24227371 chr11:82718527 RAB30 -0.3 -6.62 -0.34 1.38e-10 Obesity-related traits; LIHC cis rs9814567 0.964 rs6776203 chr3:134234345 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg08888203 chr3:10149979 C3orf24 0.52 6.26 0.32 1.14e-9 Alzheimer's disease; LIHC cis rs506338 0.517 rs471618 chr11:64465403 T/C cg03263716 chr11:64435066 NRXN2 0.34 7.31 0.37 1.95e-12 Body mass index;Urate levels; LIHC trans rs9951602 0.512 rs4799244 chr18:76649763 T/C cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09525523 chr12:16064153 DERA -0.47 -6.74 -0.34 6.73e-11 Pancreatic cancer; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg06873352 chr17:61820015 STRADA 0.6 9.32 0.45 1.51e-18 Height; LIHC cis rs8103278 0.701 rs116959973 chr19:46252333 A/T cg02376097 chr19:46275166 DMPK -0.45 -6.67 -0.34 1.04e-10 Coronary artery disease; LIHC cis rs2070488 0.775 rs9838614 chr3:38537671 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.64 -10.02 -0.48 6.9e-21 Electrocardiographic conduction measures; LIHC cis rs2243480 1.000 rs58669269 chr7:65951953 T/C cg12463550 chr7:65579703 CRCP 0.59 5.93 0.31 7.32e-9 Diabetic kidney disease; LIHC cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.6 0.46 1.76e-19 Bipolar disorder; LIHC cis rs35110281 0.807 rs9984002 chr21:45061501 T/C cg01579765 chr21:45077557 HSF2BP -0.35 -6.56 -0.33 2.01e-10 Mean corpuscular volume; LIHC trans rs61931739 0.534 rs10844800 chr12:34230734 A/G cg26384229 chr12:38710491 ALG10B 0.57 7.38 0.37 1.2e-12 Morning vs. evening chronotype; LIHC cis rs7258465 1.000 rs8103622 chr19:18572834 C/T cg10790698 chr19:18539756 SSBP4 -0.37 -7.74 -0.39 1.16e-13 Breast cancer; LIHC cis rs807669 0.868 rs762529 chr22:19170205 C/G cg02655711 chr22:19163373 SLC25A1 0.74 11.47 0.53 5.53e-26 Metabolite levels; LIHC cis rs7116495 1.000 rs2460254 chr11:71570110 A/G cg26138937 chr11:71823887 C11orf51 0.73 7.0 0.35 1.34e-11 Severe influenza A (H1N1) infection; LIHC cis rs894734 0.535 rs7301643 chr12:54325796 G/T cg17708016 chr12:54321992 NA 0.43 7.64 0.38 2.26e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs7618501 1.000 rs57648519 chr3:49813169 C/A cg21467203 chr3:49911342 NA -0.4 -6.88 -0.35 2.9100000000000002e-11 Intelligence (multi-trait analysis); LIHC cis rs4253772 0.591 rs12167567 chr22:46659942 G/C cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.76 6.97 0.35 1.6e-11 LDL cholesterol;Cholesterol, total; LIHC cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg20295408 chr7:1910781 MAD1L1 -0.49 -7.02 -0.35 1.2e-11 Bipolar disorder and schizophrenia; LIHC cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg13699009 chr12:122356056 WDR66 0.49 7.81 0.39 7.04e-14 Mean corpuscular volume; LIHC cis rs3806843 1.000 rs6898939 chr5:140169355 C/A cg19875535 chr5:140030758 IK 0.36 5.95 0.31 6.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2274273 0.870 rs28716725 chr14:55816610 T/C cg04306507 chr14:55594613 LGALS3 0.32 6.08 0.31 3.13e-9 Protein biomarker; LIHC cis rs3096299 0.559 rs9931073 chr16:89568513 G/C cg06640241 chr16:89574553 SPG7 0.65 10.79 0.5 1.45e-23 Multiple myeloma (IgH translocation); LIHC cis rs13006863 0.509 rs1667605 chr2:74374884 G/A cg23149560 chr2:74406255 MOBKL1B -0.39 -5.84 -0.3 1.22e-8 Post-traumatic stress disorder (asjusted for relatedness);Immune reponse to smallpox (secreted TNF-alpha); LIHC cis rs55882075 0.967 rs62404346 chr5:179141391 A/C cg14593053 chr5:179126677 CANX 0.39 7.26 0.37 2.62e-12 Monocyte percentage of white cells; LIHC cis rs2455799 0.613 rs2470536 chr3:15715156 G/C cg12698662 chr3:15914712 MIR563 -0.39 -7.13 -0.36 5.91e-12 Mean platelet volume; LIHC cis rs2242116 0.932 rs4683301 chr3:46931478 A/T cg27129171 chr3:47204927 SETD2 -0.46 -7.48 -0.37 6.49e-13 Birth weight; LIHC cis rs7552404 0.824 rs1251077 chr1:76189745 C/G cg03433033 chr1:76189801 ACADM -0.78 -18.01 -0.7 1.85e-51 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs597539 0.652 rs602805 chr11:68662076 A/T cg04772025 chr11:68637568 NA 0.46 6.13 0.31 2.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg06481639 chr22:41940642 POLR3H 0.7 7.28 0.37 2.38e-12 Vitiligo; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.67 9.78 0.47 4.51e-20 Lymphocyte counts; LIHC cis rs2153535 0.542 rs6905925 chr6:8440030 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs7772486 0.686 rs9403741 chr6:146030548 G/A cg13319975 chr6:146136371 FBXO30 0.34 5.79 0.3 1.56e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs477895 0.713 rs2282490 chr11:63962152 T/C cg04317338 chr11:64019027 PLCB3 0.84 10.13 0.48 2.89e-21 Mean platelet volume; LIHC cis rs16828019 0.852 rs3820090 chr1:41573652 A/G cg20697417 chr1:41786797 NA 0.32 6.06 0.31 3.52e-9 Intelligence (multi-trait analysis); LIHC cis rs4474465 0.850 rs4441045 chr11:78220436 G/T cg02023728 chr11:77925099 USP35 -0.33 -5.84 -0.3 1.2e-8 Alzheimer's disease (survival time); LIHC trans rs66887589 0.967 rs3775842 chr4:120427732 G/A cg25214090 chr10:38739885 LOC399744 0.37 6.08 0.31 3.14e-9 Diastolic blood pressure; LIHC cis rs34375054 0.738 rs10846834 chr12:125625570 A/G cg25124228 chr12:125621409 AACS -0.39 -6.51 -0.33 2.73e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs2066819 0.892 rs117305040 chr12:56657888 A/G cg26714650 chr12:56694279 CS -1.38 -13.24 -0.58 1.4e-32 Psoriasis vulgaris; LIHC cis rs904251 0.861 rs914349 chr6:37484715 A/C cg08126542 chr6:37504118 NA -0.35 -5.74 -0.3 2.05e-8 Cognitive performance; LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 11.66 0.53 1.13e-26 Height; LIHC cis rs11077998 0.903 rs8064554 chr17:80501093 A/G cg10255544 chr17:80519551 FOXK2 0.48 8.69 0.43 1.5e-16 Reticulocyte fraction of red cells; LIHC cis rs1707322 1.000 rs4390216 chr1:46266456 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.19 0.32 1.71e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7208859 0.673 rs11652370 chr17:29097223 G/A cg13385521 chr17:29058706 SUZ12P 0.79 8.06 0.4 1.32e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1552244 0.882 rs13062917 chr3:10017032 T/A cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs3768617 0.510 rs2333620 chr1:183100555 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs7833986 0.501 rs72653990 chr8:57037115 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.65 0.42 2.09e-16 Height; LIHC cis rs7224737 0.956 rs8081900 chr17:40289875 G/A cg02450064 chr17:40260053 DHX58 -0.3 -6.12 -0.31 2.53e-9 Fibrinogen levels; LIHC cis rs2455799 0.573 rs2455830 chr3:15749213 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.28 -0.37 2.26e-12 Mean platelet volume; LIHC cis rs1707322 1.000 rs785467 chr1:46521559 A/T cg06784218 chr1:46089804 CCDC17 -0.39 -6.91 -0.35 2.38e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3020736 0.500 rs6002601 chr22:42489058 A/T cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs7312933 0.701 rs10880260 chr12:42561398 A/G cg17420585 chr12:42539391 GXYLT1 -0.37 -5.95 -0.31 6.52e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1957429 0.808 rs4899150 chr14:65344400 A/G cg23373153 chr14:65346875 NA 0.83 11.9 0.54 1.49e-27 Pediatric areal bone mineral density (radius); LIHC cis rs8072100 0.840 rs56952963 chr17:45493826 T/C cg08085267 chr17:45401833 C17orf57 -0.55 -8.25 -0.41 3.46e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2274273 0.522 rs2251366 chr14:55518156 A/G cg01864836 chr14:55583639 NA -0.37 -6.29 -0.32 9.82e-10 Protein biomarker; LIHC cis rs72781680 0.846 rs55770503 chr2:24030126 A/T cg08917208 chr2:24149416 ATAD2B 0.85 7.72 0.39 1.29e-13 Lymphocyte counts; LIHC trans rs9388451 0.839 rs4897157 chr6:126102981 A/T cg05039488 chr6:79577232 IRAK1BP1 -0.54 -8.63 -0.42 2.41e-16 Brugada syndrome; LIHC cis rs2404602 0.647 rs11072620 chr15:77048770 T/A cg23625390 chr15:77176239 SCAPER -0.56 -9.45 -0.45 5.65e-19 Blood metabolite levels; LIHC cis rs999943 1.000 rs999943 chr6:33624733 A/G cg14003231 chr6:33640908 ITPR3 0.37 7.64 0.38 2.16e-13 Obesity (extreme); LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.42 -6.04 -0.31 4.13e-9 Longevity; LIHC cis rs9790314 0.586 rs1839491 chr3:161126429 C/A cg17135325 chr3:160939158 NMD3 0.47 7.11 0.36 6.79e-12 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg06453172 chr10:134556979 INPP5A -0.66 -9.26 -0.45 2.31e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs780094 0.606 rs6729709 chr2:27583156 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.39 -5.78 -0.3 1.73e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg11062466 chr8:58055876 NA 0.51 7.61 0.38 2.72e-13 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.791 rs7395713 chr11:49877887 A/G cg03929089 chr4:120376271 NA -0.89 -18.29 -0.7 1.34e-52 Height; LIHC cis rs3768617 0.510 rs10797849 chr1:183088988 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 5.05e-23 Fuchs's corneal dystrophy; LIHC cis rs2281845 0.826 rs4915484 chr1:201076917 C/G cg24849736 chr1:201084428 NA -0.33 -5.93 -0.31 7.22e-9 Permanent tooth development; LIHC cis rs1348850 0.632 rs1405718 chr2:178499809 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 8.42 0.41 1.06e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs561341 1.000 rs113676348 chr17:30244327 A/G cg13647721 chr17:30228624 UTP6 0.78 7.34 0.37 1.57e-12 Hip circumference adjusted for BMI; LIHC cis rs2576037 0.583 rs641366 chr18:44430326 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.88 -0.3 9.96e-9 Personality dimensions; LIHC cis rs10751667 0.666 rs7395823 chr11:942701 T/C cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.56e-13 Alzheimer's disease (late onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg03701779 chr10:74927978 FAM149B1;ECD -0.49 -6.33 -0.32 7.71e-10 Hepatitis; LIHC cis rs4819052 0.959 rs9976074 chr21:46655638 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.68 8.65 0.42 2.06e-16 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7095944 0.614 rs10901816 chr10:126440395 G/A cg08799069 chr10:126477246 METTL10 -0.37 -6.48 -0.33 3.29e-10 Asthma; LIHC cis rs17270561 1.000 rs12200962 chr6:25828986 T/C cg16482183 chr6:26056742 HIST1H1C 0.54 6.35 0.32 6.85e-10 Iron status biomarkers; LIHC cis rs10744422 1.000 rs3852537 chr12:123361501 T/C cg18912006 chr12:123335444 HIP1R -0.6 -7.25 -0.36 2.85e-12 Schizophrenia; LIHC cis rs1348850 0.651 rs4893935 chr2:178240601 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.75 11.47 0.53 5.53e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg10755058 chr3:40428713 ENTPD3 0.42 7.14 0.36 5.82e-12 Renal cell carcinoma; LIHC cis rs2304069 0.545 rs11167492 chr5:149403101 G/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.6 8.46 0.42 7.83e-16 HIV-1 control; LIHC trans rs11039100 1.000 rs12366070 chr11:5828394 C/T cg11650987 chr12:10280440 CLEC7A 0.4 6.05 0.31 3.89e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9583531 0.600 rs1441042 chr13:111365589 T/G cg15841412 chr13:111365552 ING1 0.51 6.5 0.33 2.86e-10 Coronary artery disease; LIHC cis rs644799 1.000 rs617999 chr11:95589935 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.88 16.32 0.66 1.13e-44 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4808199 0.947 rs4808960 chr19:19574277 G/C cg20644253 chr19:19431407 KIAA0892;SF4 0.43 6.18 0.32 1.86e-9 Nonalcoholic fatty liver disease; LIHC cis rs17685 0.884 rs8565 chr7:75630274 T/C cg04592579 chr7:75616294 TMEM120A -0.35 -6.05 -0.31 3.79e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg09913183 chr17:42254507 C17orf65;ASB16 0.7 10.47 0.49 1.95e-22 Total body bone mineral density; LIHC cis rs4561483 0.771 rs7202234 chr16:11942322 A/G cg08843971 chr16:11963173 GSPT1 0.34 6.77 0.34 5.73e-11 Testicular germ cell tumor; LIHC trans rs9929218 0.954 rs10163398 chr16:68823124 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.18 -0.4 5.53e-15 Colorectal cancer; LIHC cis rs12079745 0.590 rs7544446 chr1:169256524 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -7.4 -0.37 1.04e-12 QT interval; LIHC cis rs1419980 0.730 rs2004838 chr12:7780920 C/T cg10578777 chr12:7781093 NA -0.4 -5.83 -0.3 1.26e-8 HDL cholesterol levels; LIHC cis rs34779708 0.931 rs10508815 chr10:35332621 A/C cg03585969 chr10:35415529 CREM 0.78 11.65 0.53 1.25e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs5769765 0.908 rs9616213 chr22:50317851 T/G cg26441486 chr22:50317300 CRELD2 0.38 6.52 0.33 2.54e-10 Schizophrenia; LIHC cis rs7587476 0.906 rs3768713 chr2:215637505 G/A cg04004882 chr2:215674386 BARD1 0.5 6.05 0.31 3.85e-9 Neuroblastoma; LIHC cis rs3008870 0.755 rs2755254 chr1:67470855 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.45 0.49 2.38e-22 Lymphocyte percentage of white cells; LIHC cis rs11098499 0.954 rs10006706 chr4:120409152 A/G cg09307838 chr4:120376055 NA 0.77 11.87 0.54 1.94e-27 Corneal astigmatism; LIHC cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg00149659 chr3:10157352 C3orf10 0.61 6.71 0.34 7.86e-11 Alzheimer's disease; LIHC cis rs10751667 0.621 rs10794348 chr11:939941 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.64 -0.62 5.13e-38 Alzheimer's disease (late onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09220050 chr20:48770642 TMEM189;TMEM189-UBE2V1 -0.41 -6.29 -0.32 9.78e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4727027 0.899 rs11768971 chr7:148825826 C/G cg23583168 chr7:148888333 NA -0.74 -10.41 -0.49 3.17e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg08132940 chr7:1081526 C7orf50 -0.81 -6.83 -0.35 3.99e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs911119 1.000 rs6036476 chr20:23610308 C/G cg16589663 chr20:23618590 CST3 0.74 7.51 0.38 5.16e-13 Chronic kidney disease; LIHC cis rs1008375 1.000 rs56974987 chr4:17627856 G/A cg02297831 chr4:17616191 MED28 0.48 7.41 0.37 1.02e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg19774624 chr17:42201019 HDAC5 -0.81 -12.42 -0.56 1.73e-29 Total body bone mineral density; LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg24693881 chr1:107596107 NA 0.5 8.49 0.42 6.42e-16 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs11039798 0.528 rs10769559 chr11:49032446 T/C cg15704280 chr7:45808275 SEPT13 0.55 6.14 0.32 2.28e-9 Axial length; LIHC cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg21951975 chr1:209979733 IRF6 0.45 7.2 0.36 3.87e-12 Cleft lip with or without cleft palate; LIHC cis rs6783573 0.965 rs7650998 chr3:46607255 C/T cg21489266 chr3:46619131 LRRC2;TDGF1 0.34 5.73 0.3 2.25e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg13409248 chr3:40428643 ENTPD3 -0.51 -8.62 -0.42 2.46e-16 Renal cell carcinoma; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg03990998 chr4:15006727 CPEB2 -0.43 -6.06 -0.31 3.5e-9 Immature fraction of reticulocytes; LIHC cis rs595982 0.559 rs4802516 chr19:49366170 T/C cg15549821 chr19:49342101 PLEKHA4 -0.63 -5.82 -0.3 1.36e-8 Red cell distribution width; LIHC cis rs4474465 1.000 rs7131199 chr11:78192148 T/G cg27205649 chr11:78285834 NARS2 -0.41 -6.02 -0.31 4.44e-9 Alzheimer's disease (survival time); LIHC cis rs7116495 0.609 rs73543612 chr11:71820350 C/T cg10381502 chr11:71823885 C11orf51 1.08 9.2 0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs4713118 0.540 rs469227 chr6:27970705 A/C cg16479474 chr6:28041457 NA 0.43 6.65 0.34 1.15e-10 Parkinson's disease; LIHC cis rs5769765 0.955 rs8139758 chr22:50261123 G/T cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs9457247 1.000 rs404222 chr6:167402150 G/A cg07741184 chr6:167504864 NA 0.32 7.34 0.37 1.61e-12 Crohn's disease; LIHC cis rs1982963 0.627 rs61971552 chr14:52481524 G/T cg10843707 chr14:52510701 NID2 0.38 6.0 0.31 5.05e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4906332 1.000 rs17617935 chr14:103952886 A/T cg19000871 chr14:103996768 TRMT61A -0.47 -7.93 -0.39 3.16e-14 Coronary artery disease; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg03517284 chr6:25882590 NA -0.53 -7.46 -0.37 7.31e-13 Blood metabolite levels; LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg21724239 chr8:58056113 NA 0.58 7.69 0.38 1.63e-13 Developmental language disorder (linguistic errors); LIHC cis rs2204008 0.685 rs4556621 chr12:38187236 C/A cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg26338869 chr17:61819248 STRADA 0.49 6.54 0.33 2.19e-10 Height; LIHC cis rs11098499 0.909 rs9759478 chr4:120367998 G/A cg09307838 chr4:120376055 NA 0.77 12.02 0.55 5.13e-28 Corneal astigmatism; LIHC cis rs2645694 0.626 rs2703151 chr4:77834095 A/G cg03477792 chr4:77819574 ANKRD56 0.46 6.12 0.31 2.52e-9 Emphysema distribution in smoking; LIHC cis rs7408868 0.706 rs2238642 chr19:15282237 T/C cg09752223 chr19:15281200 NOTCH3 -0.35 -6.18 -0.32 1.82e-9 Pulse pressure; LIHC cis rs12791968 1.000 rs11038240 chr11:45002878 A/G cg11846598 chr11:44996168 LOC221122 0.46 8.09 0.4 1.07e-14 Inhibitory control; LIHC cis rs7296418 0.754 rs1619283 chr12:123717362 A/G cg05973401 chr12:123451056 ABCB9 0.44 6.55 0.33 2.15e-10 Platelet count; LIHC cis rs79149102 0.579 rs7179097 chr15:75279240 T/G cg17294928 chr15:75287854 SCAMP5 -0.47 -6.09 -0.31 3.08e-9 Lung cancer; LIHC cis rs7677751 0.767 rs890205 chr4:55063373 C/A cg17187183 chr4:55093834 PDGFRA 0.58 7.38 0.37 1.18e-12 Corneal astigmatism; LIHC cis rs10193935 0.786 rs72796504 chr2:42406728 T/C cg27598129 chr2:42591480 NA -0.74 -11.49 -0.53 4.78e-26 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18264753 chr6:138188625 TNFAIP3 0.44 6.27 0.32 1.06e-9 Lung function (FEV1/FVC); LIHC cis rs933688 0.877 rs10474352 chr5:90732225 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.33 0.72 8.32e-57 Smoking behavior; LIHC cis rs35110281 0.501 rs162381 chr21:44920915 A/G cg21573476 chr21:45109991 RRP1B 0.47 7.93 0.39 3.15e-14 Mean corpuscular volume; LIHC cis rs950169 0.922 rs12906983 chr15:84931022 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 8.7 0.43 1.42e-16 Schizophrenia; LIHC cis rs1200821 0.535 rs1208783 chr10:37767467 A/G cg25427524 chr10:38739819 LOC399744 -0.41 -6.91 -0.35 2.41e-11 Hemostatic factors and hematological phenotypes; LIHC cis rs6456156 0.586 rs12525855 chr6:167480013 T/G cg12798992 chr6:167411361 FGFR1OP 0.42 6.38 0.33 5.71e-10 Primary biliary cholangitis; LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg03188948 chr7:1209495 NA 0.43 6.04 0.31 4.08e-9 Longevity;Endometriosis; LIHC cis rs17854409 0.881 rs68066790 chr20:61487150 T/A cg06598544 chr20:61472147 COL9A3 -0.79 -7.73 -0.39 1.25e-13 Obesity-related traits; LIHC cis rs826838 0.510 rs10506129 chr12:39224242 A/T cg26384229 chr12:38710491 ALG10B 0.72 8.74 0.43 1.04e-16 Heart rate; LIHC cis rs875971 0.965 rs10267430 chr7:65743023 G/T cg11764359 chr7:65958608 NA -0.91 -16.9 -0.67 5.28e-47 Aortic root size; LIHC trans rs3783890 0.887 rs2295702 chr14:93813988 G/A cg02802420 chr16:69363236 PDF;COG8 0.33 6.29 0.32 9.92e-10 Body mass index; LIHC cis rs4575098 0.681 rs11579514 chr1:161143312 A/G cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.36 6.74 0.34 6.62e-11 Monocyte percentage of white cells; LIHC cis rs6815814 0.861 rs10012017 chr4:38784633 G/T cg06935464 chr4:38784597 TLR10 0.53 9.36 0.45 1.07e-18 Breast cancer; LIHC cis rs6598955 0.543 rs6698557 chr1:26561220 G/C cg04990556 chr1:26633338 UBXN11 0.75 11.32 0.52 1.92e-25 Obesity-related traits; LIHC trans rs877282 0.583 rs10904564 chr10:819459 C/G cg22713356 chr15:30763199 NA 0.86 7.22 0.36 3.31e-12 Uric acid levels; LIHC cis rs2286503 0.839 rs2270107 chr7:22862183 G/A cg11367502 chr7:22862612 TOMM7 0.45 7.51 0.38 5.08e-13 Fibrinogen; LIHC cis rs6570726 0.967 rs413880 chr6:145804822 G/A cg23711669 chr6:146136114 FBXO30 0.48 8.52 0.42 5.34e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg03517284 chr6:25882590 NA 0.9 12.2 0.55 1.12e-28 Blood metabolite levels; LIHC cis rs875971 1.000 rs6958277 chr7:65979349 A/G cg11764359 chr7:65958608 NA 0.91 16.91 0.67 4.71e-47 Aortic root size; LIHC cis rs2073300 0.609 rs6132606 chr20:23367453 G/A cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2251381 0.640 rs2183568 chr21:30484782 A/T cg08807101 chr21:30365312 RNF160 -0.73 -10.02 -0.48 7.12e-21 Selective IgA deficiency; LIHC cis rs6061231 0.556 rs6121571 chr20:60977323 T/G cg03945807 chr20:60948434 NA 0.38 6.08 0.31 3.13e-9 Colorectal cancer; LIHC trans rs208520 0.690 rs3846808 chr6:66818604 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.81 -8.98 -0.44 1.84e-17 Exhaled nitric oxide output; LIHC cis rs739401 0.611 rs401707 chr11:3050965 T/C cg08508325 chr11:3079039 CARS -0.32 -6.8 -0.35 4.65e-11 Longevity; LIHC cis rs7833790 0.660 rs10091077 chr8:82705464 A/G cg17211192 chr8:82754475 SNX16 -0.54 -9.8 -0.47 3.7799999999999997e-20 Diastolic blood pressure; LIHC cis rs11628318 0.853 rs8003309 chr14:103050143 C/G cg01864069 chr14:103024347 NA -0.58 -9.32 -0.45 1.47e-18 Platelet count; LIHC cis rs1371867 0.810 rs2860518 chr8:101238120 G/T cg06636551 chr8:101224915 SPAG1 0.47 8.93 0.43 2.64e-17 Atrioventricular conduction; LIHC cis rs7208859 0.673 rs11654914 chr17:29229424 C/G cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg05564831 chr3:52568323 NT5DC2 0.37 6.04 0.31 3.93e-9 Bipolar disorder; LIHC cis rs1552244 0.882 rs35056669 chr3:10014171 C/T cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs10865541 0.902 rs7593978 chr2:3415544 C/T cg11642891 chr2:3452563 TTC15 -0.39 -6.22 -0.32 1.48e-9 Obesity-related traits; LIHC cis rs968567 0.705 rs174572 chr11:61598288 C/T cg27386326 chr11:61587980 NA 0.42 6.17 0.32 1.93e-9 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs864643 1.000 rs536454 chr3:39550318 A/G cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs11098499 0.954 rs6857105 chr4:120222298 C/G cg09307838 chr4:120376055 NA 0.74 11.05 0.51 1.83e-24 Corneal astigmatism; LIHC cis rs9309473 1.000 rs13383871 chr2:73631779 T/C cg20560298 chr2:73613845 ALMS1 -0.57 -6.49 -0.33 3.04e-10 Metabolite levels; LIHC cis rs910316 0.904 rs7156089 chr14:75645527 A/G cg11812906 chr14:75593930 NEK9 -0.71 -13.35 -0.59 5.36e-33 Height; LIHC cis rs2797685 0.945 rs1773138 chr1:7891797 C/T cg04725166 chr1:7887271 PER3 -0.41 -7.3 -0.37 2e-12 Crohn's disease; LIHC cis rs9457247 1.000 rs397713 chr6:167386714 G/A cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs11718455 0.767 rs6782500 chr3:43990260 A/G cg08738300 chr3:44038990 NA -0.53 -9.31 -0.45 1.55e-18 Coronary artery disease; LIHC cis rs11630290 0.667 rs6494441 chr15:64166877 A/G cg12036633 chr15:63758958 NA 0.57 5.96 0.31 6.35e-9 Iris characteristics; LIHC cis rs919433 1.000 rs919433 chr2:198166565 G/A cg10820045 chr2:198174542 NA -0.59 -10.13 -0.48 2.93e-21 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2841277 0.741 rs9672139 chr14:105408182 T/G cg14403583 chr14:105418241 AHNAK2 -0.22 -5.91 -0.3 8.16e-9 Rheumatoid arthritis; LIHC cis rs2274273 0.905 rs28429419 chr14:55574793 T/C cg04306507 chr14:55594613 LGALS3 0.31 6.13 0.31 2.38e-9 Protein biomarker; LIHC cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg25072359 chr17:41440525 NA 0.38 6.07 0.31 3.36e-9 Menopause (age at onset); LIHC trans rs116095464 0.558 rs10055354 chr5:243794 G/A cg00938859 chr5:1591904 SDHAP3 0.56 7.13 0.36 5.85e-12 Breast cancer; LIHC cis rs6695567 0.934 rs6692772 chr1:53629190 G/A cg20326410 chr1:53600821 SLC1A7 0.3 6.32 0.32 8.26e-10 Systemic lupus erythematosus; LIHC cis rs2637266 0.967 rs6480826 chr10:78356154 A/G cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC trans rs5756813 0.727 rs4239889 chr22:38140352 T/G cg19894588 chr14:64061835 NA -0.59 -8.01 -0.4 1.82e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs28830936 0.966 rs2303516 chr15:42128568 C/G cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.85 -0.3 1.16e-8 Diastolic blood pressure; LIHC cis rs941408 0.515 rs4624312 chr19:2774460 T/C cg02580895 chr19:2754563 NA -0.46 -6.81 -0.35 4.34e-11 Total cholesterol levels; LIHC cis rs7534824 0.543 rs61780298 chr1:101402982 T/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.91 0.39 3.5e-14 Refractive astigmatism; LIHC cis rs60871478 1.000 rs4720917 chr7:806998 C/G cg04727924 chr7:799746 HEATR2 -0.58 -8.61 -0.42 2.7e-16 Cerebrospinal P-tau181p levels; LIHC cis rs2549003 0.966 rs10065633 chr5:131816716 T/C cg02551604 chr5:131831745 NA -0.43 -6.52 -0.33 2.51e-10 Asthma (sex interaction); LIHC cis rs6062302 0.522 rs2236503 chr20:62224595 G/A cg16989086 chr20:62203971 PRIC285 0.57 8.2 0.41 5.08e-15 Glioblastoma; LIHC cis rs6693567 0.586 rs12031973 chr1:150485566 T/G cg15654264 chr1:150340011 RPRD2 0.51 8.34 0.41 1.89e-15 Migraine; LIHC cis rs6547741 0.874 rs28381983 chr2:27804432 T/C cg27432699 chr2:27873401 GPN1 0.74 12.08 0.55 3.32e-28 Oral cavity cancer; LIHC trans rs11098499 0.954 rs12499324 chr4:120393786 C/T cg25214090 chr10:38739885 LOC399744 0.58 9.57 0.46 2.14e-19 Corneal astigmatism; LIHC cis rs2239547 0.657 rs13072536 chr3:52861211 A/T cg11645453 chr3:52864694 ITIH4 0.34 8.83 0.43 5.49e-17 Schizophrenia; LIHC cis rs4665809 1.000 rs11126340 chr2:26253255 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.71 -8.54 -0.42 4.37e-16 Gut microbiome composition (summer); LIHC cis rs9902453 0.619 rs2255489 chr17:28084974 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.69 -11.01 -0.51 2.46e-24 Coffee consumption (cups per day); LIHC cis rs16828019 0.852 rs3904243 chr1:41574852 T/G cg20697417 chr1:41786797 NA 0.32 6.12 0.31 2.52e-9 Intelligence (multi-trait analysis); LIHC cis rs875971 0.638 rs6960778 chr7:66071597 C/T cg14393609 chr7:65229607 NA -0.38 -6.03 -0.31 4.36e-9 Aortic root size; LIHC cis rs1559088 0.512 rs60197880 chr19:33562695 C/A cg27124370 chr19:33622961 WDR88 0.44 5.83 0.3 1.29e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs12928939 0.517 rs17358402 chr16:71967927 C/T cg03805757 chr16:71968109 PKD1L3 -0.93 -12.67 -0.57 2.02e-30 Post bronchodilator FEV1; LIHC trans rs2243480 1.000 rs73142122 chr7:65311298 C/A cg10756647 chr7:56101905 PSPH 1.11 13.27 0.58 1.06e-32 Diabetic kidney disease; LIHC trans rs4714291 1.000 rs1100098 chr6:40026044 A/G cg02267698 chr19:7991119 CTXN1 0.39 6.08 0.31 3.2e-9 Strep throat; LIHC cis rs798554 0.757 rs960273 chr7:2857876 T/C cg04166393 chr7:2884313 GNA12 0.48 6.62 0.34 1.39e-10 Height; LIHC cis rs35306767 0.903 rs11815185 chr10:923617 T/A cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs1403694 1.000 rs1624230 chr3:186438935 A/C cg12454167 chr3:186435060 KNG1 -0.27 -6.66 -0.34 1.12e-10 Blood protein levels; LIHC cis rs921968 0.612 rs832810 chr2:219322430 T/C cg02985541 chr2:219472218 PLCD4 0.47 8.94 0.44 2.53e-17 Mean corpuscular hemoglobin concentration; LIHC cis rs1983891 1.000 rs913074 chr6:41538545 T/C cg15051332 chr6:41514432 FOXP4 0.42 5.71 0.3 2.44e-8 Prostate cancer; LIHC trans rs35333254 0.588 rs1501172 chr4:14438109 G/T cg20299935 chr17:21795943 NA -0.53 -6.22 -0.32 1.46e-9 Age-related hearing impairment; LIHC cis rs61612642 0.537 rs73434275 chr6:42156239 G/A cg01092361 chr6:42185687 MRPS10 0.9 9.12 0.44 6.47e-18 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs2629751 0.512 rs2723845 chr12:104446721 T/C cg14987745 chr12:104360022 TDG -0.69 -6.85 -0.35 3.51e-11 Hepatitis C induced liver fibrosis; LIHC cis rs7772486 0.875 rs6570738 chr6:146412695 G/A cg23711669 chr6:146136114 FBXO30 0.57 9.82 0.47 3.37e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs10216189 1.000 rs7799970 chr7:5527714 G/C cg05318486 chr7:5553423 FBXL18 -0.56 -8.26 -0.41 3.27e-15 Relative hand skill in reading disability; LIHC cis rs10911232 0.507 rs10797821 chr1:183012559 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.01e-22 Hypertriglyceridemia; LIHC cis rs3768617 0.510 rs10752902 chr1:183090265 T/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs7615952 0.736 rs9862893 chr3:125686974 A/G cg05084668 chr3:125655381 ALG1L -0.7 -11.07 -0.51 1.48e-24 Blood pressure (smoking interaction); LIHC cis rs7085104 0.552 rs11191414 chr10:104601565 A/T cg15744005 chr10:104629667 AS3MT -0.42 -9.55 -0.46 2.49e-19 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6138458 1.000 rs227631 chr20:24913653 A/G cg26195577 chr20:24973756 C20orf3 1.12 14.83 0.63 9.49e-39 Blood protein levels; LIHC cis rs13161895 1.000 rs4700853 chr5:179473328 G/A cg02702477 chr5:179499311 RNF130 0.8 11.17 0.52 6.67e-25 LDL cholesterol; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg24846343 chr22:24311635 DDTL -0.55 -9.71 -0.46 7.63e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7945718 0.591 rs4489724 chr11:12684166 G/T cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.12 0.36 6.48e-12 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg09455208 chr3:40491958 NA 0.34 6.78 0.34 5.26e-11 Renal cell carcinoma; LIHC trans rs2749592 0.550 rs10764135 chr10:37866845 C/T cg17830980 chr10:43048298 ZNF37B 0.42 7.91 0.39 3.5e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6942756 0.747 rs692697 chr7:129112576 C/T cg02491457 chr7:128862824 NA 0.53 8.26 0.41 3.23e-15 White matter hyperintensity burden; LIHC cis rs11671005 0.656 rs11671092 chr19:59009109 T/C cg25952890 chr19:58913133 NA 0.68 6.45 0.33 3.82e-10 Mean platelet volume; LIHC cis rs7027203 0.828 rs10821229 chr9:96595136 A/C cg14598338 chr9:96623480 NA -0.34 -6.65 -0.34 1.13e-10 DNA methylation (variation); LIHC cis rs1577917 0.740 rs7775864 chr6:86247759 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.48 9.3 0.45 1.66e-18 Response to antipsychotic treatment; LIHC cis rs96067 0.711 rs272811 chr1:36634414 G/A cg24686825 chr1:36642396 MAP7D1 -0.63 -9.81 -0.47 3.39e-20 Corneal structure; LIHC cis rs754466 0.606 rs55854323 chr10:79589904 C/T cg17075019 chr10:79541650 NA -0.79 -11.91 -0.54 1.38e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8177179 0.967 rs4078166 chr3:133435979 C/A cg24879335 chr3:133465180 TF 0.47 11.04 0.51 1.95e-24 Iron status biomarkers (transferrin levels); LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.13 0.55 2e-28 Prudent dietary pattern; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg01874867 chr7:94954059 PON1 -0.54 -9.85 -0.47 2.65e-20 Paraoxonase activity; LIHC cis rs17021463 0.902 rs36099342 chr4:95239783 T/C cg11021082 chr4:95130006 SMARCAD1 0.48 8.75 0.43 1e-16 Testicular germ cell tumor; LIHC trans rs2739330 0.652 rs2000469 chr22:24245292 A/G cg06437703 chr8:37914619 EIF4EBP1 -0.45 -6.36 -0.33 6.4e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs8073060 0.586 rs7212488 chr17:33993476 A/T cg19694781 chr19:47549865 TMEM160 -1.27 -13.88 -0.6 4.83e-35 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.52 -0.38 4.89e-13 Lymphocyte counts; LIHC trans rs8073060 0.533 rs178736 chr17:33928158 G/T cg19694781 chr19:47549865 TMEM160 -1.26 -13.03 -0.58 9e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg25204440 chr1:209979598 IRF6 0.53 8.07 0.4 1.18e-14 Cleft lip with or without cleft palate; LIHC cis rs79387448 0.745 rs78136548 chr2:103103740 T/G cg09003973 chr2:102972529 NA 1.02 7.42 0.37 9.45e-13 Gut microbiota (bacterial taxa); LIHC cis rs12079745 0.590 rs3766088 chr1:169268692 A/T cg09363564 chr1:169337483 NME7;BLZF1 0.7 6.51 0.33 2.61e-10 QT interval; LIHC cis rs56146971 0.763 rs55950330 chr14:91872978 C/T cg16433844 chr14:91963127 SMEK1 -0.5 -5.77 -0.3 1.74e-8 Alzheimer disease and age of onset; LIHC cis rs61677309 1.000 rs1074457 chr11:118156117 A/T cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs10463316 0.862 rs13354553 chr5:150758128 G/A cg03212797 chr5:150827313 SLC36A1 -0.46 -7.08 -0.36 8.42e-12 Metabolite levels (Pyroglutamine); LIHC cis rs9612 1.000 rs2277745 chr19:44259077 C/T cg08581076 chr19:44259116 C19orf61 0.69 8.85 0.43 4.91e-17 Exhaled nitric oxide output; LIHC cis rs7208859 0.623 rs59447372 chr17:29057585 C/T cg14067834 chr17:29058358 SUZ12P 0.68 6.79 0.34 5.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11628318 0.660 rs4906242 chr14:103085063 G/A cg01864069 chr14:103024347 NA -0.46 -7.35 -0.37 1.5e-12 Platelet count; LIHC cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg25894440 chr7:65020034 NA 0.51 5.9 0.3 8.83e-9 Diabetic kidney disease; LIHC cis rs7940866 0.903 rs7130842 chr11:130836269 A/G cg12179176 chr11:130786555 SNX19 0.52 7.59 0.38 3.1400000000000003e-13 Schizophrenia; LIHC cis rs7927771 1.000 rs1317149 chr11:47486885 C/T cg20135002 chr11:47629003 NA -0.58 -10.1 -0.48 3.59e-21 Subjective well-being; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg15383120 chr6:291909 DUSP22 -0.51 -7.01 -0.35 1.31e-11 Menopause (age at onset); LIHC trans rs13301469 0.831 rs12685989 chr9:3909039 C/T cg10281478 chr7:95402528 DYNC1I1 -0.39 -6.16 -0.32 2.08e-9 Schizophrenia; LIHC cis rs477692 0.935 rs557158 chr10:131420534 C/T cg19680672 chr10:131412579 MGMT -0.44 -6.85 -0.35 3.35e-11 Response to temozolomide; LIHC cis rs41271473 0.526 rs10916339 chr1:228716894 C/T cg10167378 chr1:228756711 NA 0.6 6.05 0.31 3.89e-9 Chronic lymphocytic leukemia; LIHC cis rs780094 0.585 rs3739095 chr2:27556721 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -6.42 -0.33 4.55e-10 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg18654377 chr3:49208889 KLHDC8B -0.5 -5.93 -0.31 7.29e-9 Menarche (age at onset); LIHC cis rs4727027 1.000 rs4727027 chr7:148869277 C/T cg23583168 chr7:148888333 NA -0.72 -10.17 -0.48 2.08e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs5753037 0.702 rs131301 chr22:30185889 A/T cg01021169 chr22:30184971 ASCC2 -0.36 -6.93 -0.35 2.1e-11 Type 1 diabetes; LIHC cis rs67478160 0.619 rs12886363 chr14:104273786 T/C cg01849466 chr14:104193079 ZFYVE21 -0.44 -6.83 -0.35 3.85e-11 Schizophrenia; LIHC cis rs7613875 0.578 rs2624822 chr3:50107219 T/C cg24110177 chr3:50126178 RBM5 0.56 9.16 0.44 4.94e-18 Body mass index; LIHC cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.9 0.3 8.79e-9 Bipolar disorder; LIHC cis rs7216064 1.000 rs62084249 chr17:65874998 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6752107 0.791 rs3792106 chr2:234190740 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.41 5.86 0.3 1.1e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2412488 0.927 rs56998298 chr4:54248698 A/G cg22241045 chr4:54363911 LNX1 -0.4 -6.48 -0.33 3.15e-10 DNA methylation (variation); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01059432 chr1:45279684 BTBD19 0.43 6.24 0.32 1.26e-9 Lung function (FEV1/FVC); LIHC cis rs1577917 0.740 rs2758842 chr6:86308731 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.29 -0.32 9.88e-10 Response to antipsychotic treatment; LIHC cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg20607798 chr8:58055168 NA 0.5 6.12 0.31 2.55e-9 Developmental language disorder (linguistic errors); LIHC cis rs2292096 0.925 rs4554747 chr1:200698597 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.46 -6.02 -0.31 4.41e-9 Epilepsy; LIHC cis rs7258015 1.000 rs10408916 chr19:10447770 T/G cg13981319 chr19:10446556 ICAM3 0.46 7.21 0.36 3.68e-12 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.48 -5.98 -0.31 5.47e-9 Diastolic blood pressure; LIHC cis rs6502050 0.799 rs11491185 chr17:80151101 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.79 -0.3 1.56e-8 Life satisfaction; LIHC cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.22 0.55 9.48e-29 Alzheimer's disease; LIHC cis rs722599 0.748 rs11623342 chr14:75347937 A/C cg08847533 chr14:75593920 NEK9 -0.54 -8.58 -0.42 3.41e-16 IgG glycosylation; LIHC cis rs1048238 0.506 rs7547314 chr1:16186722 G/A cg00529422 chr1:16285251 ZBTB17 -0.34 -6.64 -0.34 1.25e-10 Systolic blood pressure; LIHC cis rs57244997 0.725 rs73028496 chr6:162422243 A/G cg17173639 chr6:162384350 PARK2 -0.53 -6.86 -0.35 3.26e-11 Mosquito bite size; LIHC trans rs6598955 0.671 rs17257169 chr1:26570009 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.81 -8.77 -0.43 8.38e-17 Obesity-related traits; LIHC cis rs9814567 0.929 rs13088413 chr3:134309977 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.91 0.3 8.47e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4332037 0.539 rs62444881 chr7:2052318 C/T cg23422044 chr7:1970798 MAD1L1 -0.52 -6.09 -0.31 2.96e-9 Bipolar disorder; LIHC cis rs7131987 0.903 rs2194519 chr12:29423583 C/T cg21522988 chr12:29376872 FAR2 -0.28 -6.35 -0.32 6.82e-10 QT interval; LIHC cis rs7312933 0.558 rs1796381 chr12:42842475 C/T cg17420585 chr12:42539391 GXYLT1 -0.34 -5.72 -0.3 2.35e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6598955 0.724 rs10902737 chr1:26635716 G/A cg00852783 chr1:26633632 UBXN11 0.53 8.8 0.43 6.98e-17 Obesity-related traits; LIHC trans rs2832191 0.716 rs7509628 chr21:30454252 C/T cg14791747 chr16:20752902 THUMPD1 -0.45 -6.34 -0.32 7.19e-10 Dental caries; LIHC cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9309473 1.000 rs6753344 chr2:73653138 C/T cg20560298 chr2:73613845 ALMS1 0.51 5.91 0.3 8.06e-9 Metabolite levels; LIHC cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg03264133 chr6:25882463 NA -0.64 -7.9 -0.39 3.93e-14 Intelligence (multi-trait analysis); LIHC cis rs1580019 0.587 rs6968990 chr7:32552159 C/T cg06627557 chr7:32535165 LSM5;AVL9 -1.14 -26.59 -0.82 3.05e-85 Cognitive ability; LIHC cis rs3008870 0.755 rs4486425 chr1:67460791 T/C cg08660285 chr1:67390436 MIER1;WDR78 -0.64 -10.79 -0.5 1.5e-23 Lymphocyte percentage of white cells; LIHC cis rs1395 0.778 rs11693660 chr2:27468856 T/C cg23587288 chr2:27483067 SLC30A3 -0.32 -5.91 -0.3 8.32e-9 Blood metabolite levels; LIHC cis rs2439831 1.000 rs2584726 chr15:43715382 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.73 0.43 1.14e-16 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09656405 chr15:69745057 RPLP1 0.46 6.93 0.35 2.09e-11 Pancreatic cancer; LIHC cis rs9393777 1.000 rs9393777 chr6:26942027 T/C cg12826209 chr6:26865740 GUSBL1 0.79 7.79 0.39 7.86e-14 Intelligence (multi-trait analysis); LIHC cis rs6930083 0.527 rs9470367 chr6:36626932 G/C cg08179530 chr6:36648295 CDKN1A -0.66 -9.6 -0.46 1.74e-19 Coronary artery disease; LIHC cis rs992157 0.764 rs4423579 chr2:219185033 G/T cg00012203 chr2:219082015 ARPC2 0.76 10.74 0.5 2.16e-23 Colorectal cancer; LIHC cis rs10411936 0.720 rs4808513 chr19:16580498 G/C cg10248733 chr19:16607483 C19orf44;CALR3 0.48 6.41 0.33 4.7e-10 White blood cell count;Multiple sclerosis; LIHC cis rs10870270 0.912 rs7079991 chr10:133736130 A/G cg17892150 chr10:133769511 PPP2R2D -0.69 -13.16 -0.58 2.7e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7408868 1.000 rs7245814 chr19:15274503 A/G cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs12188164 0.543 rs2672757 chr5:454732 A/G cg16584290 chr5:462447 EXOC3 0.36 5.94 0.31 7.07e-9 Cystic fibrosis severity; LIHC cis rs2637030 0.559 rs7728496 chr5:52867330 G/T cg06476337 chr5:52856530 NDUFS4 -0.39 -6.26 -0.32 1.12e-9 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs4713118 0.739 rs2893931 chr6:27748010 G/A cg20933634 chr6:27740509 NA 0.45 5.94 0.31 6.83e-9 Parkinson's disease; LIHC cis rs7647973 0.925 rs6446256 chr3:49224210 A/G cg07636037 chr3:49044803 WDR6 0.51 6.49 0.33 3.08e-10 Menarche (age at onset); LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg27432699 chr2:27873401 GPN1 -0.54 -7.84 -0.39 5.98e-14 Total body bone mineral density; LIHC trans rs941408 1.000 rs1640266 chr19:2787832 T/G cg19676328 chr12:49525230 TUBA1B -0.37 -6.08 -0.31 3.23e-9 Total cholesterol levels; LIHC cis rs968567 0.689 rs61897795 chr11:61618169 A/G cg06781209 chr11:61594997 FADS2 -0.72 -6.38 -0.33 5.92e-10 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs1801251 0.963 rs7562712 chr2:233606580 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.13 0.52 9.01e-25 Coronary artery disease; LIHC cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg05527609 chr1:210001259 C1orf107 0.43 6.37 0.33 6e-10 Cleft lip with or without cleft palate; LIHC cis rs896854 0.516 rs12679044 chr8:95891356 C/A cg23172400 chr8:95962367 TP53INP1 -0.36 -7.71 -0.38 1.35e-13 Type 2 diabetes; LIHC cis rs7772486 0.686 rs857882 chr6:145969716 T/G cg13319975 chr6:146136371 FBXO30 0.37 6.02 0.31 4.42e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg03452623 chr4:187889614 NA -0.32 -8.31 -0.41 2.33e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11243680 chr12:31881778 AMN1 -0.53 -6.61 -0.34 1.51e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3812831 0.695 rs6560935 chr13:114945867 G/A cg08824895 chr13:115047677 UPF3A 0.45 6.64 0.34 1.2e-10 Schizophrenia; LIHC trans rs11039798 1.000 rs7123704 chr11:48580535 G/A cg15704280 chr7:45808275 SEPT13 0.61 6.29 0.32 9.63e-10 Axial length; LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg06558623 chr16:89946397 TCF25 1.0 15.26 0.64 1.86e-40 Skin colour saturation; LIHC cis rs2295359 1.000 rs4655524 chr1:67629469 G/A cg12940439 chr1:67600707 NA 0.38 6.84 0.35 3.65e-11 Psoriasis; LIHC cis rs8180040 0.764 rs13061071 chr3:47138708 G/A cg16586182 chr3:47516702 SCAP -0.49 -8.91 -0.43 3.15e-17 Colorectal cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14929913 chr10:1147979 WDR37 0.41 6.04 0.31 3.96e-9 Longevity; LIHC cis rs7937890 0.559 rs1116739 chr11:14489182 G/C cg22961513 chr11:14280813 SPON1 -0.39 -5.73 -0.3 2.22e-8 Mitochondrial DNA levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24419099 chr11:47270565 NR1H3;ACP2 0.46 7.04 0.36 1.09e-11 Cognitive function; LIHC cis rs11628318 0.570 rs2896450 chr14:103076595 T/C cg12046867 chr14:103022105 NA -0.48 -6.84 -0.35 3.7e-11 Platelet count; LIHC cis rs7772486 0.597 rs6570732 chr6:146245151 G/A cg13319975 chr6:146136371 FBXO30 0.59 9.05 0.44 1.12e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs4975709 0.610 rs6886669 chr5:1867830 T/C cg14773178 chr5:1868261 NA 0.27 7.05 0.36 1e-11 Cardiovascular disease risk factors; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19569686 chr19:1555141 MEX3D 0.44 6.25 0.32 1.21e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7296418 0.699 rs11057219 chr12:123750073 T/C cg05973401 chr12:123451056 ABCB9 0.41 6.02 0.31 4.4e-9 Platelet count; LIHC cis rs763121 0.853 rs5750627 chr22:38982321 A/G cg21395723 chr22:39101663 GTPBP1 0.43 7.36 0.37 1.41e-12 Menopause (age at onset); LIHC cis rs2607426 0.681 rs2545760 chr19:41299824 G/A cg20631044 chr19:41255890 C19orf54;SNRPA -0.51 -5.73 -0.3 2.15e-8 Blood protein levels; LIHC cis rs896854 0.654 rs896847 chr8:95972551 G/A cg09323728 chr8:95962352 TP53INP1 -0.28 -6.06 -0.31 3.54e-9 Type 2 diabetes; LIHC cis rs12188164 0.543 rs2434695 chr5:464177 C/G cg26076054 chr5:421317 AHRR 0.27 5.99 0.31 5.35e-9 Cystic fibrosis severity; LIHC cis rs2153535 0.580 rs1932275 chr6:8442333 T/A cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs2292096 1.000 rs72746858 chr1:200783153 T/C cg11814564 chr1:200748674 CAMSAP1L1 -0.45 -5.92 -0.3 7.95e-9 Epilepsy; LIHC cis rs61990749 0.597 rs759808 chr14:78250845 T/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.64 -0.38 2.22e-13 Fibroblast growth factor basic levels; LIHC cis rs4665809 0.941 rs3177055 chr2:26359315 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.78 -9.86 -0.47 2.44e-20 Gut microbiome composition (summer); LIHC cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.95 15.21 0.64 2.77e-40 Platelet count; LIHC cis rs11628318 0.515 rs7142819 chr14:103133385 A/G cg12046867 chr14:103022105 NA 0.39 6.04 0.31 4.06e-9 Platelet count; LIHC cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg04944784 chr2:26401820 FAM59B 0.67 7.25 0.36 2.83e-12 Gut microbiome composition (summer); LIHC cis rs34375054 0.752 rs35505608 chr12:125662252 G/T cg25124228 chr12:125621409 AACS -0.41 -6.67 -0.34 1.06e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs712039 0.652 rs67879888 chr17:35795312 A/G cg16670864 chr17:35848621 DUSP14 0.34 5.91 0.3 8.19e-9 Tuberculosis; LIHC cis rs2066819 1.000 rs59626664 chr12:56636975 C/G cg26714650 chr12:56694279 CS -1.33 -12.81 -0.57 5.98e-31 Psoriasis vulgaris; LIHC cis rs922107 0.967 rs6428556 chr1:90019581 C/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.77 -0.39 9.19e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs904251 0.620 rs883372 chr6:37477605 A/C cg01843034 chr6:37503916 NA -0.41 -6.4 -0.33 5.17e-10 Cognitive performance; LIHC cis rs10752881 0.875 rs10797825 chr1:183024581 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.68 0.5 3.74e-23 Colorectal cancer; LIHC cis rs6088590 0.561 rs6088527 chr20:33155841 C/T cg08999081 chr20:33150536 PIGU 0.69 13.69 0.59 2.57e-34 Coronary artery disease; LIHC cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg22800045 chr5:56110881 MAP3K1 0.68 8.74 0.43 1.03e-16 Initial pursuit acceleration; LIHC cis rs477895 1.000 rs11600990 chr11:64082807 C/T cg04317338 chr11:64019027 PLCB3 0.84 8.09 0.4 1.06e-14 Mean platelet volume; LIHC cis rs11112613 0.609 rs11112585 chr12:105933442 A/G cg03607813 chr12:105948248 NA -0.56 -10.12 -0.48 3.05e-21 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs921968 0.541 rs12987171 chr2:219327030 G/C cg02985541 chr2:219472218 PLCD4 0.44 7.26 0.37 2.69e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs2421770 0.530 rs11033084 chr11:35367408 T/G cg13971030 chr11:35366721 SLC1A2 -0.44 -7.44 -0.37 8.06e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs7927592 0.956 rs12274114 chr11:68255577 A/C cg20283391 chr11:68216788 NA -0.5 -7.49 -0.38 5.74e-13 Total body bone mineral density; LIHC trans rs6073597 0.967 rs6124676 chr20:43647261 G/A cg14213297 chr9:130870109 SLC25A25 -0.35 -6.22 -0.32 1.49e-9 Positive affect; LIHC cis rs2204008 0.605 rs4608149 chr12:38132057 G/C cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs7937890 0.559 rs2575831 chr11:14486194 A/T cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs1005277 0.540 rs4934907 chr10:38015230 A/C cg25427524 chr10:38739819 LOC399744 -0.63 -12.14 -0.55 1.97e-28 Extrinsic epigenetic age acceleration; LIHC cis rs7829975 0.682 rs7013471 chr8:8687325 A/G cg06636001 chr8:8085503 FLJ10661 -0.41 -6.02 -0.31 4.5e-9 Mood instability; LIHC cis rs6582630 0.537 rs2204006 chr12:38407098 A/G cg26384229 chr12:38710491 ALG10B 0.58 8.04 0.4 1.5e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs6831352 0.879 rs2602888 chr4:100041706 C/T cg12011299 chr4:100065546 ADH4 0.63 10.44 0.49 2.55e-22 Alcohol dependence; LIHC cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg18252515 chr7:66147081 NA -1.26 -16.85 -0.67 8.29e-47 Diabetic kidney disease; LIHC cis rs8067545 0.641 rs169412 chr17:19851875 G/T cg13482628 chr17:19912719 NA 0.4 6.68 0.34 9.93e-11 Schizophrenia; LIHC cis rs8084351 0.501 rs11876419 chr18:50627202 G/C cg24270629 chr18:50823537 DCC 0.42 6.43 0.33 4.18e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs800082 0.698 rs800074 chr3:144347638 A/G cg24215973 chr2:240111563 HDAC4 -0.62 -9.65 -0.46 1.18e-19 Smoking behavior; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg10081115 chr2:190686883 PMS1 0.45 6.13 0.31 2.43e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9649465 0.967 rs10487806 chr7:123314446 C/T cg03229431 chr7:123269106 ASB15 0.37 8.04 0.4 1.52e-14 Migraine; LIHC cis rs655641 1.000 rs2509608 chr11:85779297 T/G cg09030501 chr11:85779252 PICALM -0.51 -6.01 -0.31 4.83e-9 Platelet count; LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.73 10.76 0.5 1.88e-23 Lymphocyte counts; LIHC cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg25072359 chr17:41440525 NA 0.38 5.97 0.31 5.92e-9 Menopause (age at onset); LIHC cis rs9309473 0.950 rs6546847 chr2:73785358 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.77 -0.34 5.48e-11 Metabolite levels; LIHC cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg20607798 chr8:58055168 NA 0.65 7.65 0.38 2.05e-13 Developmental language disorder (linguistic errors); LIHC cis rs1075232 1.000 rs67634762 chr15:31748055 G/T cg01030201 chr15:31746330 NA -0.86 -6.79 -0.34 5e-11 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs7216064 0.773 rs74541577 chr17:65853651 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs11098499 0.644 rs3806808 chr4:120551085 A/C cg25214090 chr10:38739885 LOC399744 0.49 7.88 0.39 4.27e-14 Corneal astigmatism; LIHC cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg18404041 chr3:52824283 ITIH1 -0.63 -10.37 -0.49 4.28e-22 Bipolar disorder; LIHC cis rs11122272 0.701 rs743120 chr1:231531232 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs1784581 0.588 rs1784606 chr6:162405992 A/T cg17173639 chr6:162384350 PARK2 -0.58 -10.65 -0.5 4.57e-23 Itch intensity from mosquito bite; LIHC cis rs8114671 0.527 rs6060068 chr20:33415820 T/A cg07148914 chr20:33460835 GGT7 0.6 8.88 0.43 3.98e-17 Height; LIHC cis rs2153535 0.623 rs6597338 chr6:8533508 A/C cg21535247 chr6:8435926 SLC35B3 0.65 8.63 0.42 2.43e-16 Motion sickness; LIHC cis rs7572733 0.555 rs1837495 chr2:198921201 A/G cg10820045 chr2:198174542 NA -0.41 -6.2 -0.32 1.65e-9 Dermatomyositis; LIHC trans rs916888 0.821 rs199514 chr17:44856881 G/A cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9628987 0.569 rs3753275 chr1:8425900 T/C cg20416874 chr1:8611966 RERE 0.5 6.05 0.31 3.71e-9 Breast cancer; LIHC cis rs12586317 0.547 rs10146699 chr14:35483577 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.35 0.59 5.37e-33 Psoriasis; LIHC cis rs11676348 0.846 rs7594532 chr2:219008000 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.46 -6.31 -0.32 8.83e-10 Ulcerative colitis; LIHC cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg16434002 chr17:42200994 HDAC5 -0.52 -7.56 -0.38 3.7e-13 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07282944 chr12:48499338 SENP1;PFKM 0.5 7.09 0.36 7.76e-12 Pancreatic cancer; LIHC trans rs877282 0.891 rs34383514 chr10:800181 T/C cg22713356 chr15:30763199 NA 1.38 12.73 0.57 1.14e-30 Uric acid levels; LIHC cis rs7264396 0.622 rs3787165 chr20:34228946 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -9.55 -0.46 2.51e-19 Total cholesterol levels; LIHC cis rs875971 0.798 rs6460304 chr7:65964728 G/A cg18876405 chr7:65276391 NA 0.35 6.45 0.33 3.83e-10 Aortic root size; LIHC cis rs7208859 0.623 rs28627615 chr17:29145817 G/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1348850 0.526 rs78587445 chr2:178461339 G/T cg27490568 chr2:178487706 NA -1.12 -11.66 -0.53 1.15e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs13113518 0.783 rs6843722 chr4:56331332 A/C cg15358633 chr12:38710606 ALG10B 0.42 6.05 0.31 3.82e-9 Height; LIHC cis rs4073582 0.595 rs801734 chr11:65931216 T/C cg14036092 chr11:66035641 RAB1B 0.4 5.97 0.31 6.01e-9 Gout; LIHC trans rs494453 0.583 rs559981 chr1:112219338 C/T cg13908074 chr2:149259371 MBD5 0.4 6.44 0.33 3.96e-10 Osteoporosis-related phenotypes; LIHC trans rs1814175 0.781 rs2866734 chr11:49886338 A/G cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.15e-11 Height; LIHC cis rs2404602 0.692 rs34181263 chr15:77065388 C/T cg03037974 chr15:76606532 NA 0.74 14.5 0.62 1.85e-37 Blood metabolite levels; LIHC cis rs62064224 0.902 rs17732573 chr17:30627664 C/T cg25833597 chr17:30823145 MYO1D -0.55 -7.43 -0.37 8.96e-13 Schizophrenia; LIHC cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg13866156 chr1:1669148 SLC35E2 -0.71 -13.64 -0.59 4.1e-34 Body mass index; LIHC cis rs6662572 0.806 rs12047498 chr1:45954632 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.59 6.11 0.31 2.7e-9 Blood protein levels; LIHC cis rs265548 0.510 rs28415068 chr19:17910582 T/A cg04517722 chr19:17905589 B3GNT3 0.46 7.07 0.36 8.85e-12 Tumor biomarkers; LIHC cis rs17685 0.712 rs1859794 chr7:75821544 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.36 -5.82 -0.3 1.34e-8 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7546668 1.000 rs12741552 chr1:15853276 T/C cg11706911 chr1:15910989 AGMAT 0.44 6.82 0.35 4.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs4268898 0.722 rs4665253 chr2:24382546 G/A cg06627628 chr2:24431161 ITSN2 0.44 6.21 0.32 1.51e-9 Asthma; LIHC cis rs11122272 0.701 rs2011383 chr1:231479788 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -10.95 -0.51 4e-24 Hemoglobin concentration; LIHC cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg06634786 chr22:41940651 POLR3H -0.78 -8.56 -0.42 3.9e-16 Vitiligo; LIHC cis rs4759375 1.000 rs12317103 chr12:123802814 T/C cg00376283 chr12:123451042 ABCB9 -0.5 -6.4 -0.33 5.02e-10 HDL cholesterol; LIHC trans rs11088226 0.681 rs16989507 chr21:33939509 T/G cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.06e-34 Gastritis; LIHC cis rs950776 0.647 rs495956 chr15:78869930 C/T cg06917634 chr15:78832804 PSMA4 -0.59 -7.98 -0.4 2.3e-14 Sudden cardiac arrest; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19379625 chr4:71859087 DCK 0.42 6.31 0.32 8.6e-10 Pancreatic cancer; LIHC cis rs79976124 0.837 rs10455591 chr6:66650584 A/G cg07460842 chr6:66804631 NA 0.65 6.88 0.35 2.89e-11 Type 2 diabetes; LIHC cis rs903552 0.736 rs2412008 chr15:102006841 C/T cg00659931 chr15:102010125 PCSK6 -0.51 -6.84 -0.35 3.75e-11 Diabetic kidney disease; LIHC trans rs3780486 0.505 rs1411609 chr9:33137303 C/T cg04842962 chr6:43655489 MRPS18A 0.89 18.51 0.71 1.68e-53 IgG glycosylation; LIHC cis rs7945705 0.902 rs1560569 chr11:8939887 C/T cg12365402 chr11:9010492 NRIP3 -0.3 -7.72 -0.39 1.27e-13 Hemoglobin concentration; LIHC cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg11644478 chr21:40555479 PSMG1 0.84 10.61 0.5 6.44e-23 Cognitive function; LIHC cis rs7129220 0.660 rs61878632 chr11:10136032 A/C cg01453529 chr11:10209919 SBF2 -0.39 -7.02 -0.35 1.22e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs1801251 1.000 rs2012221 chr2:233566848 T/C cg25237894 chr2:233734115 C2orf82 0.56 10.93 0.51 4.67e-24 Coronary artery disease; LIHC cis rs9902453 0.654 rs3794809 chr17:28531258 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.85 0.43 4.91e-17 Coffee consumption (cups per day); LIHC cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.547 rs11714419 chr3:52628816 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.03 0.44 1.29e-17 Bipolar disorder; LIHC cis rs35883536 0.611 rs72977390 chr1:101107147 C/T cg14515779 chr1:101123966 NA -0.59 -11.19 -0.52 5.38e-25 Monocyte count; LIHC cis rs1008375 0.931 rs1860592 chr4:17577028 C/G cg16339924 chr4:17578868 LAP3 0.45 6.22 0.32 1.44e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2439831 0.850 rs7183809 chr15:44120868 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.33 0.41 2.02e-15 Lung cancer in ever smokers; LIHC cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg21644426 chr2:191273491 MFSD6 0.54 7.55 0.38 3.92e-13 Pulse pressure; LIHC cis rs797680 0.856 rs2031226 chr1:93786764 G/T cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.04 -0.31 3.95e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.58 -8.37 -0.41 1.52e-15 Lymphocyte counts; LIHC trans rs5756813 0.661 rs11703407 chr22:38200124 C/T cg19894588 chr14:64061835 NA -0.69 -10.03 -0.48 6.37e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs9590974 0.663 rs842408 chr13:47228097 T/A cg04092803 chr13:47240378 LRCH1 0.26 5.74 0.3 2.14e-8 PR segment; LIHC cis rs832187 0.666 rs2241823 chr3:63965093 C/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.47 -6.51 -0.33 2.73e-10 Schizophrenia; LIHC cis rs3204270 0.759 rs8071492 chr17:79682650 G/A cg18367735 chr17:79674897 NA 0.72 8.06 0.4 1.31e-14 Dental caries; LIHC cis rs965469 1.000 rs6037556 chr20:3317890 G/C cg25506879 chr20:3388711 C20orf194 -0.58 -7.06 -0.36 9.15e-12 IFN-related cytopenia; LIHC cis rs763121 0.651 rs738249 chr22:39037979 T/C cg21395723 chr22:39101663 GTPBP1 0.37 5.72 0.3 2.3e-8 Menopause (age at onset); LIHC cis rs10847980 0.590 rs78462864 chr12:123365867 C/T cg18912006 chr12:123335444 HIP1R 0.76 7.12 0.36 6.42e-12 Adiponectin levels; LIHC cis rs1034435 0.962 rs1894542 chr22:48890335 G/C cg05992904 chr22:48892994 FAM19A5 -0.5 -9.97 -0.47 1.04e-20 Late-onset Alzheimer's disease; LIHC trans rs637571 0.780 rs677029 chr11:65683531 A/G cg17712092 chr4:129076599 LARP1B 0.88 17.17 0.68 4.41e-48 Eosinophil percentage of white cells; LIHC cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg10896456 chr17:42255109 ASB16;C17orf65 0.52 9.46 0.46 5.22e-19 Total body bone mineral density; LIHC cis rs2112347 0.502 rs34339 chr5:74931333 G/T cg00601450 chr5:74908170 NA -0.74 -9.64 -0.46 1.27e-19 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg05665937 chr4:1216051 CTBP1 0.45 6.29 0.32 9.72e-10 Obesity-related traits; LIHC cis rs11676348 0.846 rs7607437 chr2:219008392 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.43 -5.9 -0.3 8.61e-9 Ulcerative colitis; LIHC cis rs7772486 0.727 rs11155442 chr6:146140725 T/C cg23711669 chr6:146136114 FBXO30 0.65 11.75 0.54 5.2e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs9814567 1.000 rs11928499 chr3:134232350 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs77633900 0.772 rs2957607 chr15:76686527 A/G cg21673338 chr15:77095150 SCAPER 0.53 5.92 0.3 7.98e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs9911578 0.935 rs2302189 chr17:56584205 A/C cg05425664 chr17:57184151 TRIM37 0.56 8.15 0.4 6.96e-15 Intelligence (multi-trait analysis); LIHC trans rs7395662 0.591 rs4882138 chr11:48619321 A/G cg03929089 chr4:120376271 NA -0.4 -6.09 -0.31 3.02e-9 HDL cholesterol; LIHC cis rs7511006 0.895 rs5771270 chr22:50682865 G/A cg16473166 chr22:50639996 SELO 0.49 6.86 0.35 3.3e-11 Obesity-related traits; LIHC cis rs9473924 0.505 rs28360639 chr6:50783501 G/A cg14470998 chr6:50812995 TFAP2B 0.98 10.74 0.5 2.24e-23 Body mass index; LIHC cis rs10838687 0.736 rs7120158 chr11:47265194 G/C cg25783544 chr11:47291846 MADD 0.46 5.89 0.3 9.29e-9 Proinsulin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16872847 chr19:39893195 NA 0.44 6.17 0.32 1.9e-9 Lung function (FEV1/FVC); LIHC cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.47e-18 Bipolar disorder; LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg10150615 chr22:24372951 LOC391322 -0.53 -7.58 -0.38 3.37e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg02359409 chr6:42947317 PEX6 -0.48 -6.83 -0.35 3.93e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9649465 1.000 rs2109723 chr7:123325339 A/G cg03229431 chr7:123269106 ASB15 -0.38 -8.18 -0.4 5.61e-15 Migraine; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15378686 chr17:62492736 POLG2 0.47 6.23 0.32 1.38e-9 Pancreatic cancer; LIHC cis rs10197940 0.662 rs10175134 chr2:152299355 G/A cg06191203 chr2:152266755 RIF1 -0.48 -8.03 -0.4 1.58e-14 Lung cancer; LIHC cis rs17384381 0.953 rs12717763 chr1:85808164 A/T cg16011679 chr1:85725395 C1orf52 0.77 8.22 0.41 4.14e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs950169 0.686 rs12906474 chr15:85109237 A/G cg03959625 chr15:84868606 LOC388152 0.42 5.87 0.3 1.05e-8 Schizophrenia; LIHC cis rs11098499 0.955 rs35434465 chr4:120169378 C/G cg09307838 chr4:120376055 NA 0.74 10.86 0.51 8.1e-24 Corneal astigmatism; LIHC cis rs2274273 0.840 rs2341622 chr14:55737243 C/A cg01864836 chr14:55583639 NA -0.41 -7.45 -0.37 7.75e-13 Protein biomarker; LIHC trans rs60843830 1.000 rs10193373 chr2:281886 T/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.67 9.55 0.46 2.59e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs4076764 0.914 rs10753614 chr1:163365903 C/T cg24596788 chr1:163392923 NA 0.21 6.52 0.33 2.47e-10 Motion sickness; LIHC cis rs7769051 1.000 rs3813347 chr6:133119778 G/A cg22852734 chr6:133119734 C6orf192 0.98 9.39 0.45 8.92e-19 Type 2 diabetes nephropathy; LIHC cis rs3862030 0.720 rs11593526 chr10:104228017 G/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.47 -7.02 -0.35 1.21e-11 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg24101359 chr6:42928495 GNMT 0.45 5.72 0.3 2.31e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6500602 0.727 rs12443748 chr16:4541831 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.49 0.38 6e-13 Schizophrenia; LIHC cis rs2439831 0.867 rs2255042 chr15:43834318 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.7 -11.19 -0.52 5.59e-25 Lung cancer in ever smokers; LIHC cis rs12579753 1.000 rs17692461 chr12:82171755 C/G cg07988820 chr12:82153109 PPFIA2 -0.46 -5.71 -0.3 2.41e-8 Resting heart rate; LIHC cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg25894440 chr7:65020034 NA -0.51 -5.83 -0.3 1.26e-8 Diabetic kidney disease; LIHC cis rs4908760 0.827 rs6692693 chr1:8707116 T/G cg20416874 chr1:8611966 RERE -0.64 -13.11 -0.58 4.36e-32 Vitiligo; LIHC cis rs10744422 1.000 rs10744434 chr12:123368419 T/A cg22842854 chr12:123319900 HIP1R -0.64 -8.31 -0.41 2.28e-15 Schizophrenia; LIHC cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg18404041 chr3:52824283 ITIH1 0.55 8.84 0.43 5.25e-17 Bipolar disorder; LIHC cis rs1165668 1.000 rs1165670 chr12:104318406 G/A cg21863207 chr12:104234989 NT5DC3 0.4 6.36 0.33 6.43e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs26868 0.740 rs26869 chr16:2248786 T/C cg25665528 chr16:2260870 C16orf79 -0.35 -6.02 -0.31 4.43e-9 Height; LIHC cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg25072359 chr17:41440525 NA 0.38 6.01 0.31 4.86e-9 Menopause (age at onset); LIHC cis rs1801251 0.727 rs6437071 chr2:233568793 G/A cg25237894 chr2:233734115 C2orf82 0.41 7.85 0.39 5.35e-14 Coronary artery disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15094104 chr5:133406808 NA 0.35 6.11 0.31 2.74e-9 Cognitive function; LIHC cis rs9303401 0.614 rs34920953 chr17:56589406 G/A cg25039879 chr17:56429692 SUPT4H1 0.74 8.14 0.4 7.56e-15 Cognitive test performance; LIHC cis rs12711979 0.765 rs7559345 chr2:3818523 G/A cg17052675 chr2:3827356 NA -0.42 -7.27 -0.37 2.49e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs9993613 1.000 rs28627296 chr4:73487092 G/A cg15102770 chr4:73434591 ADAMTS3 -0.37 -5.77 -0.3 1.79e-8 Hip circumference adjusted for BMI;Height; LIHC cis rs875971 0.660 rs10272357 chr7:66063074 G/A cg00343986 chr7:65444356 GUSB -0.38 -5.71 -0.3 2.45e-8 Aortic root size; LIHC trans rs7193541 0.684 rs4888264 chr16:74681632 T/G cg23598604 chr1:99732472 LPPR4 -0.3 -6.23 -0.32 1.37e-9 Multiple myeloma; LIHC cis rs3736485 0.966 rs8040080 chr15:51904459 C/T cg08986416 chr15:51914746 DMXL2 -0.47 -6.97 -0.35 1.64e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2625529 0.938 rs2723343 chr15:72108269 C/T cg16672083 chr15:72433130 SENP8 -0.34 -6.23 -0.32 1.36e-9 Red blood cell count; LIHC cis rs7618501 0.602 rs34831713 chr3:50118748 T/C cg21467203 chr3:49911342 NA 0.44 7.76 0.39 1.01e-13 Intelligence (multi-trait analysis); LIHC cis rs7818688 0.697 rs3802192 chr8:95987471 C/T cg16049864 chr8:95962084 TP53INP1 0.59 6.42 0.33 4.5e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4474465 0.790 rs6592790 chr11:78262618 T/C cg27205649 chr11:78285834 NARS2 0.44 6.77 0.34 5.56e-11 Alzheimer's disease (survival time); LIHC cis rs477895 0.838 rs12794145 chr11:64006484 C/T cg04317338 chr11:64019027 PLCB3 0.88 10.72 0.5 2.63e-23 Mean platelet volume; LIHC cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg03034668 chr16:1723424 CRAMP1L -0.36 -6.41 -0.33 4.89e-10 Coronary artery disease; LIHC cis rs798554 0.644 rs7783400 chr7:2894434 A/C cg13628971 chr7:2884303 GNA12 -0.52 -9.07 -0.44 9.52e-18 Height; LIHC trans rs6901152 0.525 rs4896651 chr6:143691393 A/G cg25622597 chr3:49449489 RHOA;TCTA -0.43 -6.59 -0.34 1.65e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs1005277 0.579 rs2474569 chr10:38383491 C/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs10876993 0.789 rs1689600 chr12:58049645 A/T cg18357645 chr12:58087776 OS9 0.53 8.58 0.42 3.26e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs1983891 0.955 rs2025645 chr6:41519654 A/G cg20194872 chr6:41519635 FOXP4 0.4 6.48 0.33 3.16e-10 Prostate cancer; LIHC cis rs9430161 0.579 rs7542164 chr1:11040223 G/A cg02454025 chr1:11042201 C1orf127 0.74 13.42 0.59 2.89e-33 Ewing sarcoma; LIHC trans rs2727020 0.658 rs10839269 chr11:49385596 A/G cg15704280 chr7:45808275 SEPT13 -0.95 -19.17 -0.72 3.84e-56 Coronary artery disease; LIHC cis rs9640161 0.659 rs7788316 chr7:150013995 A/T cg21361702 chr7:150065534 REPIN1 0.47 6.58 0.34 1.77e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg16822855 chr3:40428330 ENTPD3 0.34 6.23 0.32 1.34e-9 Renal cell carcinoma; LIHC trans rs9641123 0.639 rs2677095 chr7:93251234 C/T cg09745688 chr16:2908918 PRSS22 -0.36 -6.34 -0.32 7.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs8060686 0.545 rs117751972 chr16:68171968 C/T cg09835421 chr16:68378352 PRMT7 -0.54 -6.05 -0.31 3.78e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs4409675 0.576 rs6564 chr1:28212975 A/G cg23691781 chr1:28212827 C1orf38 -0.31 -7.31 -0.37 1.86e-12 Corneal astigmatism; LIHC cis rs860295 0.676 rs2666826 chr1:155658085 T/C cg02153340 chr1:155202674 NA -0.33 -6.1 -0.31 2.87e-9 Body mass index; LIHC cis rs9543976 0.800 rs4885318 chr13:76151537 G/A cg01531495 chr13:76123901 UCHL3 0.51 6.15 0.32 2.2e-9 Diabetic retinopathy; LIHC cis rs4665809 0.938 rs6742226 chr2:26342537 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.61 -0.42 2.81e-16 Gut microbiome composition (summer); LIHC cis rs60871478 1.000 rs12531530 chr7:827366 T/C cg04727924 chr7:799746 HEATR2 -0.63 -8.63 -0.42 2.42e-16 Cerebrospinal P-tau181p levels; LIHC trans rs7874142 0.714 rs10776907 chr9:137692739 T/G cg18109838 chr5:88185987 MEF2C -0.36 -6.94 -0.35 2.01e-11 Longevity; LIHC cis rs6426558 0.515 rs7543579 chr1:227377699 A/T cg10327440 chr1:227177885 CDC42BPA -0.45 -6.99 -0.35 1.46e-11 Neutrophil percentage of white cells; LIHC cis rs10131894 0.611 rs175000 chr14:75436367 T/C cg08847533 chr14:75593920 NEK9 -0.83 -16.32 -0.66 1.14e-44 Coronary artery disease; LIHC cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 10.71 0.5 2.92e-23 Platelet count; LIHC cis rs7937682 0.632 rs11214029 chr11:111761230 C/T cg09085632 chr11:111637200 PPP2R1B 0.92 12.9 0.57 2.77e-31 Primary sclerosing cholangitis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg02760007 chr6:43139670 SRF -0.44 -6.39 -0.33 5.35e-10 Systolic blood pressure; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg09455208 chr3:40491958 NA 0.4 7.93 0.39 3.04e-14 Renal cell carcinoma; LIHC cis rs11212260 0.655 rs74862732 chr11:107173483 T/G cg25435332 chr11:107328525 CWF19L2 0.74 6.86 0.35 3.29e-11 IgG glycosylation; LIHC cis rs60871478 1.000 rs62432253 chr7:802928 A/G cg04727924 chr7:799746 HEATR2 -0.62 -8.52 -0.42 5.15e-16 Cerebrospinal P-tau181p levels; LIHC cis rs12291225 0.545 rs11023187 chr11:14345559 T/G cg19336497 chr11:14380999 RRAS2 -0.67 -14.14 -0.61 4.54e-36 Sense of smell; LIHC cis rs6582630 0.555 rs10880421 chr12:38423015 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.81 0.5 1.27e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs2303745 0.589 rs11086065 chr19:17395003 A/G cg10664184 chr19:17420304 DDA1 0.45 5.78 0.3 1.69e-8 Systemic lupus erythematosus; LIHC cis rs11671005 0.735 rs3088284 chr19:58929427 G/A cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs4820294 1.000 rs62236668 chr22:38063870 G/A cg00142150 chr22:38071001 LGALS1 0.7 11.28 0.52 2.75e-25 Fat distribution (HIV); LIHC cis rs77633900 0.772 rs2469554 chr15:76642700 G/C cg21673338 chr15:77095150 SCAPER -0.53 -5.89 -0.3 9.09e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs35146811 0.807 rs6953441 chr7:99617067 G/A cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.4 5.74 0.3 2.08e-8 Coronary artery disease; LIHC cis rs8010715 0.816 rs6573565 chr14:24594733 A/G cg23112188 chr14:24563095 PCK2 0.28 5.78 0.3 1.69e-8 IgG glycosylation; LIHC cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.91 0.35 2.34e-11 Gut microbiome composition (summer); LIHC trans rs7246657 0.943 rs1559229 chr19:37876197 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.6 0.34 1.61e-10 Coronary artery calcification; LIHC cis rs7618501 0.501 rs7627864 chr3:49926613 C/G cg05623727 chr3:50126028 RBM5 0.35 5.88 0.3 9.73e-9 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.727 rs55939215 chr16:4541390 C/G cg08645402 chr16:4508243 NA 0.43 7.89 0.39 4.07e-14 Schizophrenia; LIHC cis rs7296418 0.630 rs11057238 chr12:123767971 C/A cg00376283 chr12:123451042 ABCB9 0.61 10.15 0.48 2.49e-21 Platelet count; LIHC cis rs12765878 1.000 rs11191865 chr10:105672842 G/A cg11005552 chr10:105648138 OBFC1 0.4 6.22 0.32 1.43e-9 Coronary artery disease; LIHC cis rs11931598 0.514 rs10937779 chr4:7039326 G/A cg02503808 chr4:7069936 GRPEL1 0.55 9.13 0.44 6.21e-18 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs965469 0.779 rs6037516 chr20:3233142 C/G cg25506879 chr20:3388711 C20orf194 -0.51 -6.24 -0.32 1.3e-9 IFN-related cytopenia; LIHC cis rs7617773 0.780 rs6782166 chr3:48351683 A/G cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg00280220 chr17:61926910 NA 0.38 6.37 0.33 6.22e-10 Prudent dietary pattern; LIHC cis rs798554 0.759 rs798495 chr7:2797267 T/C cg19717773 chr7:2847554 GNA12 -0.42 -6.64 -0.34 1.23e-10 Height; LIHC cis rs8103278 0.793 rs59093775 chr19:46374037 G/A cg11657440 chr19:46296263 DMWD -0.46 -6.89 -0.35 2.69e-11 Coronary artery disease; LIHC cis rs7264396 0.563 rs2425084 chr20:34301871 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.93 -0.43 2.59e-17 Total cholesterol levels; LIHC cis rs9303401 0.659 rs62083525 chr17:56658088 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.34 0.58 5.79e-33 Cognitive test performance; LIHC cis rs1371867 0.875 rs1788174 chr8:101330957 C/G cg06636551 chr8:101224915 SPAG1 0.48 9.03 0.44 1.3e-17 Atrioventricular conduction; LIHC cis rs2302190 0.882 rs7210714 chr17:56675666 A/C cg05425664 chr17:57184151 TRIM37 -0.47 -5.85 -0.3 1.18e-8 Vitamin D levels; LIHC cis rs13161895 1.000 rs864482 chr5:179427873 A/G cg02702477 chr5:179499311 RNF130 0.74 10.22 0.48 1.4e-21 LDL cholesterol; LIHC cis rs12478296 1.000 rs66466023 chr2:243046151 T/G cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.09e-27 Obesity-related traits; LIHC cis rs2115630 1.000 rs7183401 chr15:85371944 G/T cg12501888 chr15:85177176 SCAND2 -0.49 -7.48 -0.38 6.14e-13 P wave terminal force; LIHC trans rs867371 1.000 rs4778982 chr15:82475272 T/G cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.75 -0.34 6.31e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs6684514 0.961 rs10908503 chr1:156300683 C/T cg16558208 chr1:156270281 VHLL 0.54 10.31 0.49 7.15e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs96067 0.805 rs12033825 chr1:36600311 C/T cg24686825 chr1:36642396 MAP7D1 -0.53 -7.64 -0.38 2.15e-13 Corneal structure; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg22903471 chr2:27725779 GCKR -0.46 -7.92 -0.39 3.38e-14 Total body bone mineral density; LIHC cis rs7264396 0.790 rs6060565 chr20:34285442 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.69 -11.77 -0.54 4.61e-27 Total cholesterol levels; LIHC cis rs68170813 0.523 rs11762152 chr7:106811374 G/A cg02696742 chr7:106810147 HBP1 -0.53 -6.28 -0.32 1.05e-9 Coronary artery disease; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg09367891 chr1:107599246 PRMT6 -0.73 -12.03 -0.55 4.8e-28 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs2243480 1.000 rs56016656 chr7:65383481 C/T cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs6570726 0.935 rs422540 chr6:145837815 G/T cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7572733 0.555 rs10202569 chr2:198934726 C/G cg00792783 chr2:198669748 PLCL1 0.42 5.94 0.31 7.19e-9 Dermatomyositis; LIHC cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs10492096 1.000 rs10492096 chr12:6580582 A/G cg13857086 chr12:6580257 VAMP1 0.62 6.18 0.32 1.78e-9 Hip geometry; LIHC cis rs10089 1.000 rs77086350 chr5:127494431 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.41 0.33 4.86e-10 Ileal carcinoids; LIHC cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg18252515 chr7:66147081 NA -1.26 -17.06 -0.68 1.18e-47 Diabetic kidney disease; LIHC cis rs600231 0.706 rs4244811 chr11:65320780 G/A cg10628098 chr11:65292300 SCYL1 -0.38 -5.95 -0.31 6.47e-9 Bone mineral density; LIHC cis rs6723226 0.679 rs116617324 chr2:32622709 C/T cg02381751 chr2:32503542 YIPF4 -0.58 -8.7 -0.43 1.44e-16 Intelligence (multi-trait analysis); LIHC cis rs796364 1.000 rs1509835 chr2:200814809 C/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.23 0.41 4.04e-15 Schizophrenia; LIHC cis rs9948 0.655 rs75763821 chr2:97392694 G/A cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg22907277 chr7:1156413 C7orf50 0.43 6.04 0.31 4.01e-9 Longevity;Endometriosis; LIHC cis rs9858542 0.953 rs9841110 chr3:49492481 C/G cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs8073060 0.927 rs7502331 chr17:33868858 A/G cg19694781 chr19:47549865 TMEM160 0.64 6.83 0.35 3.97e-11 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9790314 1.000 rs7647327 chr3:161016421 T/C cg03342759 chr3:160939853 NMD3 -0.73 -8.95 -0.44 2.34e-17 Morning vs. evening chronotype; LIHC cis rs2286885 1.000 rs10760439 chr9:129250830 A/C cg15282417 chr9:129245246 FAM125B 0.4 6.34 0.32 7.13e-10 Intraocular pressure; LIHC cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg03517284 chr6:25882590 NA -0.61 -8.55 -0.42 4.09e-16 Blood metabolite levels; LIHC cis rs5758511 0.680 rs5758681 chr22:42645091 A/G cg00645731 chr22:42541494 CYP2D7P1 0.53 8.5 0.42 5.79e-16 Birth weight; LIHC cis rs4862750 0.872 rs4862748 chr4:187877388 C/T cg10295955 chr4:187884368 NA 0.63 11.51 0.53 4e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9467773 1.000 rs9461271 chr6:26554968 G/A cg09904177 chr6:26538194 HMGN4 0.65 13.83 0.6 7.52e-35 Intelligence (multi-trait analysis); LIHC cis rs9814567 0.896 rs11915964 chr3:134348930 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.6 10.12 0.48 3.21e-21 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs780094 0.606 rs6729709 chr2:27583156 G/A cg21747090 chr2:27597821 SNX17 -0.43 -6.38 -0.33 5.6e-10 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs17376456 0.877 rs114256265 chr5:93473130 T/A cg25358565 chr5:93447407 FAM172A 1.11 10.2 0.48 1.72e-21 Diabetic retinopathy; LIHC cis rs921968 0.541 rs4674314 chr2:219423520 A/G cg02985541 chr2:219472218 PLCD4 -0.41 -6.65 -0.34 1.13e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9640161 0.789 rs1464753 chr7:150021350 G/C cg17279839 chr7:150038598 RARRES2 0.51 10.71 0.5 2.84e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.79 0.39 8.12e-14 Prudent dietary pattern; LIHC cis rs477692 0.569 rs10764885 chr10:131310207 G/A cg19680672 chr10:131412579 MGMT -0.38 -5.71 -0.3 2.43e-8 Response to temozolomide; LIHC cis rs909341 0.868 rs2315009 chr20:62344140 C/G cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.56e-11 Atopic dermatitis; LIHC cis rs8180040 0.932 rs1531875 chr3:47452786 G/A cg27129171 chr3:47204927 SETD2 0.57 9.8 0.47 3.69e-20 Colorectal cancer; LIHC cis rs854765 0.647 rs741782 chr17:18019712 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.39 7.34 0.37 1.54e-12 Total body bone mineral density; LIHC cis rs9368481 0.569 rs10946868 chr6:26887930 A/G cg12292205 chr6:26970375 C6orf41 0.42 7.1 0.36 7.41e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs2153535 0.601 rs4960414 chr6:8438541 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.3e-16 Motion sickness; LIHC cis rs9858542 0.953 rs7622302 chr3:49547561 T/C cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2228479 0.850 rs1800339 chr16:89839637 C/A cg14709524 chr16:89940631 TCF25 0.47 5.79 0.3 1.58e-8 Skin colour saturation; LIHC cis rs941873 0.868 rs1483733 chr10:81130036 A/G cg09469691 chr10:81107165 PPIF 0.58 8.58 0.42 3.3e-16 Height; LIHC cis rs7223966 0.961 rs112709843 chr17:61836936 T/A cg05941027 chr17:61774174 LIMD2 0.38 7.98 0.4 2.31e-14 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1904096 0.506 rs12511433 chr4:95162425 G/A cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.31 -0.45 1.63e-18 Type 2 diabetes; LIHC cis rs35110281 0.774 rs162404 chr21:44963264 G/A cg04455712 chr21:45112962 RRP1B 0.44 7.34 0.37 1.58e-12 Mean corpuscular volume; LIHC cis rs7772486 0.754 rs702304 chr6:145990797 A/G cg05347473 chr6:146136440 FBXO30 -0.4 -6.36 -0.33 6.35e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2425143 1.000 rs11696947 chr20:34312658 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs7707921 0.881 rs324910 chr5:81400264 A/C cg15871215 chr5:81402204 ATG10 -0.63 -6.26 -0.32 1.12e-9 Breast cancer; LIHC cis rs2580764 0.566 rs2968827 chr2:55297629 C/G cg09592903 chr2:55203963 RTN4 0.62 11.46 0.53 5.95e-26 Mean platelet volume; LIHC cis rs16828019 0.929 rs12037037 chr1:41698256 C/T cg03962019 chr1:41807865 NA 0.5 7.32 0.37 1.84e-12 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.658 rs7528773 chr1:150915875 G/A cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.6 9.22 0.45 3.11e-18 Height; LIHC cis rs6445975 0.715 rs3773006 chr3:58269539 C/T cg23715586 chr3:58305044 RPP14 -0.38 -6.34 -0.32 7.22e-10 Systemic lupus erythematosus; LIHC trans rs4843747 0.749 rs12102841 chr16:88072574 C/G cg09572067 chr16:29127029 RRN3P2 -0.56 -8.94 -0.44 2.52e-17 Menopause (age at onset); LIHC trans rs800082 0.668 rs9876975 chr3:144292255 G/A cg24215973 chr2:240111563 HDAC4 -0.56 -8.64 -0.42 2.26e-16 Smoking behavior; LIHC cis rs2842992 0.789 rs2475566 chr6:160148741 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.54 9.41 0.45 7.69e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs10791097 0.667 rs12363163 chr11:130744509 A/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9457247 0.935 rs427824 chr6:167403918 T/G cg23791538 chr6:167370224 RNASET2 -0.57 -8.93 -0.43 2.7e-17 Crohn's disease; LIHC cis rs807029 0.533 rs735137 chr10:102735835 C/G cg27255678 chr10:102756921 LZTS2 0.52 7.37 0.37 1.31e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs10202249 0.587 rs75553848 chr2:154068889 C/T cg26927150 chr5:137523911 CDC23 0.39 6.04 0.31 4.03e-9 Conotruncal heart defects (inherited effects); LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg21747090 chr2:27597821 SNX17 -0.39 -5.77 -0.3 1.79e-8 Total body bone mineral density; LIHC cis rs7772486 0.790 rs2253880 chr6:146200774 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.93 0.31 7.39e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs526821 0.595 rs485555 chr11:55323570 A/G cg15704280 chr7:45808275 SEPT13 0.51 7.72 0.39 1.32e-13 Pediatric bone mineral density (spine); LIHC cis rs16854884 0.586 rs6796460 chr3:143756367 G/A cg06585982 chr3:143692056 C3orf58 0.59 7.7 0.38 1.46e-13 Economic and political preferences (feminism/equality); LIHC trans rs6945071 0.590 rs17322566 chr7:26108984 C/T cg16105687 chr19:22805801 NA 0.56 6.27 0.32 1.08e-9 Superior frontal gyrus grey matter volume; LIHC cis rs6964587 0.967 rs6970743 chr7:91744311 C/G cg17063962 chr7:91808500 NA 1.02 19.7 0.73 2.9e-58 Breast cancer; LIHC cis rs2228479 0.850 rs11645240 chr16:89837326 T/C cg14709524 chr16:89940631 TCF25 0.47 5.74 0.3 2.05e-8 Skin colour saturation; LIHC cis rs11122272 0.735 rs2247124 chr1:231493687 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.16 -0.52 6.99e-25 Hemoglobin concentration; LIHC cis rs12980942 0.872 rs7257583 chr19:41788117 T/C cg25627403 chr19:41769009 HNRNPUL1 0.5 6.3 0.32 9.22e-10 Coronary artery disease; LIHC trans rs8073060 0.586 rs2626625 chr17:34027607 C/G cg19694781 chr19:47549865 TMEM160 -1.19 -12.33 -0.55 3.78e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9611519 0.754 rs4820435 chr22:41652846 G/T cg06634786 chr22:41940651 POLR3H -0.54 -6.2 -0.32 1.61e-9 Neuroticism; LIHC cis rs7618501 0.966 rs13063621 chr3:49821625 T/C cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.03e-11 Intelligence (multi-trait analysis); LIHC cis rs600806 0.745 rs4246517 chr1:110007636 G/C cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.78 -0.39 8.73e-14 Intelligence (multi-trait analysis); LIHC cis rs12960505 0.506 rs2134296 chr18:50999730 G/A cg24270629 chr18:50823537 DCC -0.48 -6.7 -0.34 8.65e-11 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg06640241 chr16:89574553 SPG7 0.85 16.34 0.66 9.49e-45 Multiple myeloma (IgH translocation); LIHC cis rs10744422 0.920 rs10773657 chr12:123327900 C/A cg18912006 chr12:123335444 HIP1R -0.6 -7.27 -0.37 2.39e-12 Schizophrenia; LIHC cis rs892961 0.932 rs66886702 chr17:75412714 G/A cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs7220401 0.521 rs2278217 chr17:27904617 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.49 7.31 0.37 1.86e-12 Coronary artery disease; LIHC cis rs12744310 1.000 rs7553908 chr1:41768241 G/T cg03962019 chr1:41807865 NA 0.4 6.49 0.33 3.01e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg12311346 chr5:56204834 C5orf35 -0.58 -7.53 -0.38 4.48e-13 Initial pursuit acceleration; LIHC cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg22105103 chr4:187893119 NA 0.36 9.05 0.44 1.06e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs1538970 0.962 rs7544178 chr1:45819069 C/T cg05343316 chr1:45956843 TESK2 0.59 8.84 0.43 5.05e-17 Platelet count; LIHC cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.63 -0.38 2.34e-13 Bipolar disorder; LIHC cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg05552183 chr6:42928497 GNMT 0.69 10.52 0.49 1.28e-22 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs60871478 0.730 rs13222476 chr7:826630 T/C cg04727924 chr7:799746 HEATR2 -0.58 -7.91 -0.39 3.67e-14 Cerebrospinal P-tau181p levels; LIHC cis rs6502050 0.799 rs34795957 chr17:80118013 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs703842 0.616 rs10783850 chr12:58229377 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.68 9.39 0.45 8.92e-19 Multiple sclerosis; LIHC cis rs6952808 0.929 rs2280546 chr7:1976863 G/A cg20295408 chr7:1910781 MAD1L1 -0.45 -6.54 -0.33 2.28e-10 Bipolar disorder and schizophrenia; LIHC cis rs7238033 0.624 rs4316845 chr18:43309135 G/T cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs7666738 0.753 rs28463863 chr4:98844444 T/C cg05340658 chr4:99064831 C4orf37 0.64 11.61 0.53 1.67e-26 Colonoscopy-negative controls vs population controls; LIHC trans rs4927850 1.000 rs4927848 chr3:195738406 A/G cg16724585 chr3:197361211 NA -0.47 -6.25 -0.32 1.21e-9 Pancreatic cancer; LIHC cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg14078730 chr11:63896557 MACROD1 -0.37 -5.82 -0.3 1.34e-8 Mean platelet volume; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg02290350 chr8:58132656 NA 0.5 10.51 0.49 1.39e-22 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg22907277 chr7:1156413 C7orf50 0.55 8.44 0.42 8.87e-16 Longevity;Endometriosis; LIHC cis rs17685 0.743 rs10277259 chr7:75802674 A/C cg04592579 chr7:75616294 TMEM120A 0.41 7.0 0.35 1.34e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7100689 0.556 rs3120976 chr10:82025682 C/A cg00277334 chr10:82204260 NA -0.49 -5.99 -0.31 5.29e-9 Post bronchodilator FEV1; LIHC cis rs61440199 0.818 rs73818816 chr3:20148316 C/G cg00235661 chr3:20228976 SGOL1 -0.4 -5.73 -0.3 2.25e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs72781680 1.000 rs72781648 chr2:24210333 T/C cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs6912958 0.781 rs4707376 chr6:88270947 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.3 -5.73 -0.3 2.21e-8 Monocyte percentage of white cells; LIHC cis rs9733 0.596 rs6678013 chr1:150623285 T/G cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs6748734 1.000 rs7604393 chr2:241825034 T/G cg08694578 chr2:241835147 C2orf54 -0.49 -6.76 -0.34 5.92e-11 Urinary metabolites; LIHC cis rs8180040 0.726 rs2061197 chr3:47001350 C/T cg27129171 chr3:47204927 SETD2 -0.64 -10.74 -0.5 2.21e-23 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13190986 chr12:133263482 PXMP2;POLE -0.57 -7.88 -0.39 4.42e-14 Pancreatic cancer; LIHC cis rs694739 1.000 rs1783521 chr11:64106291 T/C cg23796481 chr11:64053134 BAD;GPR137 0.59 8.37 0.41 1.46e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs11229555 1.000 rs12787765 chr11:58400686 G/A cg15696309 chr11:58395628 NA -0.71 -8.75 -0.43 1.02e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs17376456 1.000 rs17323433 chr5:93551028 G/A cg25358565 chr5:93447407 FAM172A 1.08 9.8 0.47 3.72e-20 Diabetic retinopathy; LIHC cis rs1008375 1.000 rs1860596 chr4:17660082 C/T cg16339924 chr4:17578868 LAP3 0.44 6.1 0.31 2.84e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg11062466 chr8:58055876 NA 0.51 7.2 0.36 3.97e-12 Developmental language disorder (linguistic errors); LIHC cis rs6977660 0.507 rs4719580 chr7:19784847 G/T cg07541023 chr7:19748670 TWISTNB 0.42 6.28 0.32 1.03e-9 Thyroid stimulating hormone; LIHC cis rs12079745 0.793 rs10919110 chr1:169214293 G/C cg09363564 chr1:169337483 NME7;BLZF1 -0.75 -6.99 -0.35 1.44e-11 QT interval; LIHC cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg02951883 chr7:2050386 MAD1L1 -0.64 -9.97 -0.47 1.01e-20 Bipolar disorder and schizophrenia; LIHC cis rs7845219 0.525 rs3019175 chr8:95949013 G/A cg13393036 chr8:95962371 TP53INP1 -0.3 -6.02 -0.31 4.42e-9 Type 2 diabetes; LIHC cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 10.62 0.5 5.7e-23 Platelet count; LIHC cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg12310025 chr6:25882481 NA 0.39 5.96 0.31 6.29e-9 Height; LIHC cis rs763121 0.853 rs35565791 chr22:39063011 C/A cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs2842992 1.000 rs2758322 chr6:160075188 G/T cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.18 0.4 5.61e-15 Age-related macular degeneration (geographic atrophy); LIHC cis rs3617 0.532 rs9836499 chr3:52904524 G/T cg11645453 chr3:52864694 ITIH4 -0.22 -5.71 -0.3 2.46e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9596863 1.000 rs9596860 chr13:54431215 G/A ch.13.53330881F chr13:54432880 NA 0.46 6.2 0.32 1.66e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs7927771 0.524 rs7124396 chr11:47787434 T/G cg20307385 chr11:47447363 PSMC3 -0.65 -9.85 -0.47 2.68e-20 Subjective well-being; LIHC cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg12373951 chr3:133503437 NA 0.5 8.26 0.41 3.34e-15 Iron status biomarkers; LIHC cis rs9916302 0.904 rs7501488 chr17:37576417 T/G cg07936489 chr17:37558343 FBXL20 -0.85 -13.3 -0.58 7.92e-33 Glomerular filtration rate (creatinine); LIHC cis rs10861342 0.892 rs77497436 chr12:105636896 C/G cg23923672 chr12:105501055 KIAA1033 0.62 6.99 0.35 1.49e-11 IgG glycosylation; LIHC cis rs853679 0.517 rs9468292 chr6:28095355 G/A cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs9733 0.596 rs72702536 chr1:150662574 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.29 0.32 9.8e-10 Tonsillectomy; LIHC trans rs61931739 0.500 rs11053246 chr12:34516620 C/T cg26384229 chr12:38710491 ALG10B 0.79 9.79 0.47 4.2e-20 Morning vs. evening chronotype; LIHC cis rs1707322 1.000 rs4641257 chr1:46353589 G/A cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.78e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs208520 0.661 rs4710566 chr6:66848538 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.73 -8.08 -0.4 1.12e-14 Exhaled nitric oxide output; LIHC cis rs8060686 0.698 rs8044558 chr16:68210165 T/C cg05110241 chr16:68378359 PRMT7 -0.51 -6.03 -0.31 4.14e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg11644478 chr21:40555479 PSMG1 0.8 9.75 0.47 5.54e-20 Cognitive function; LIHC cis rs7903847 0.642 rs11189180 chr10:99143529 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.23e-11 Prudent dietary pattern; LIHC cis rs2625529 0.824 rs7182776 chr15:72462831 A/G cg16672083 chr15:72433130 SENP8 0.31 5.86 0.3 1.08e-8 Red blood cell count; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs8078723 0.866 rs11078934 chr17:38189793 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.51 -8.34 -0.41 1.89e-15 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7197653 0.748 rs11350 chr16:68335392 A/G cg05110241 chr16:68378359 PRMT7 -0.85 -9.33 -0.45 1.41e-18 Magnesium levels; LIHC trans rs6489882 0.867 rs7305035 chr12:113365803 T/C cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs67460515 0.926 rs11715591 chr3:161043137 C/T cg17135325 chr3:160939158 NMD3 0.55 7.76 0.39 1.01e-13 Parkinson's disease; LIHC cis rs8077889 0.871 rs16940243 chr17:41900003 C/G cg26893861 chr17:41843967 DUSP3 0.95 11.14 0.52 8.8e-25 Triglycerides; LIHC cis rs896854 0.818 rs896855 chr8:95959808 A/G cg23172400 chr8:95962367 TP53INP1 -0.38 -8.93 -0.43 2.6e-17 Type 2 diabetes; LIHC cis rs6738485 0.561 rs7590731 chr2:106810233 C/A cg15412446 chr2:106886593 NA 0.39 6.02 0.31 4.62e-9 Pursuit maintenance gain;Pursuit maintenance gain in psychotic disorders; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13446153 chr8:41435704 AGPAT6 -0.39 -6.08 -0.31 3.19e-9 Pancreatic cancer; LIHC cis rs9443189 0.813 rs3798439 chr6:76566734 T/G cg01950844 chr6:76311363 SENP6 -0.53 -6.79 -0.34 4.88e-11 Prostate cancer; LIHC cis rs7129220 0.557 rs61878580 chr11:10080572 G/A cg01453529 chr11:10209919 SBF2 -0.4 -7.0 -0.35 1.37e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25654301 chr17:73511699 TSEN54;CASKIN2 -0.42 -6.44 -0.33 4.09e-10 Cognitive function; LIHC cis rs7945718 0.875 rs7924501 chr11:12813870 A/G cg25843174 chr11:12811716 TEAD1 0.35 7.97 0.4 2.43e-14 Educational attainment (years of education); LIHC cis rs11098499 0.865 rs28634456 chr4:120375778 A/G cg09307838 chr4:120376055 NA 0.75 11.34 0.52 1.56e-25 Corneal astigmatism; LIHC cis rs7635838 0.892 rs66974661 chr3:11482729 A/G cg00170343 chr3:11313890 ATG7 0.43 6.73 0.34 7.15e-11 HDL cholesterol; LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg02353165 chr6:42928485 GNMT 0.76 11.72 0.54 6.98e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4319547 0.956 rs7397990 chr12:123119472 T/C cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.08 -0.36 8.36e-12 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27333517 chr8:92083018 OTUD6B 0.42 6.33 0.32 7.7e-10 Cognitive function; LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg05590025 chr7:65112418 INTS4L2 0.45 6.75 0.34 6.33e-11 Calcium levels; LIHC cis rs80282103 0.618 rs11819230 chr10:1128812 A/G cg08668510 chr10:1095578 IDI1 0.68 6.62 0.34 1.41e-10 Glomerular filtration rate (creatinine); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22828804 chr20:3140466 UBOX5;FASTKD5 -0.38 -6.06 -0.31 3.53e-9 Cognitive function; LIHC cis rs6952809 0.532 rs2023969 chr7:2449980 T/C cg23289794 chr7:2394357 EIF3B -0.62 -6.13 -0.31 2.47e-9 Multiple sclerosis; LIHC cis rs801193 1.000 rs7788576 chr7:66148302 G/A cg00343986 chr7:65444356 GUSB -0.39 -5.85 -0.3 1.14e-8 Aortic root size; LIHC cis rs11229555 0.609 rs4519113 chr11:58216825 T/C cg15696309 chr11:58395628 NA -0.64 -7.47 -0.37 6.89e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs8117834 0.574 rs73076232 chr20:8081611 C/A cg00593689 chr4:53575888 NA 0.37 6.28 0.32 1.02e-9 Chronic kidney disease; LIHC cis rs892961 0.899 rs72896162 chr17:75412521 A/G cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs9399135 0.967 rs13218642 chr6:135309940 A/G cg22676075 chr6:135203613 NA 0.39 6.35 0.32 6.71e-10 Red blood cell count; LIHC cis rs9911578 0.900 rs7214335 chr17:57158840 G/A cg12560992 chr17:57184187 TRIM37 0.94 16.81 0.67 1.18e-46 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs7275874 chr21:46671223 C/T cg11663144 chr21:46675770 NA -0.32 -5.95 -0.31 6.7e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.55 7.81 0.39 7.06e-14 Lymphocyte counts; LIHC cis rs4474465 1.000 rs10899509 chr11:78170811 C/T cg27205649 chr11:78285834 NARS2 -0.37 -5.86 -0.3 1.11e-8 Alzheimer's disease (survival time); LIHC cis rs78545713 0.649 rs41266811 chr6:26216656 T/C cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs2576037 0.526 rs11082562 chr18:44522671 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -6.96 -0.35 1.75e-11 Personality dimensions; LIHC cis rs4790333 0.967 rs2002863 chr17:2269769 C/T cg02569219 chr17:2266849 SGSM2 0.53 7.16 0.36 4.87e-12 Proinsulin levels; LIHC cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg03517284 chr6:25882590 NA -0.44 -6.74 -0.34 6.81e-11 Height; LIHC cis rs7914558 1.000 rs7914558 chr10:104775908 G/A cg15744005 chr10:104629667 AS3MT -0.39 -8.75 -0.43 1.02e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC trans rs11264799 0.598 rs79853736 chr1:157732091 A/C cg08109850 chr2:219773886 NA -0.42 -6.05 -0.31 3.9e-9 IgA nephropathy; LIHC cis rs6138458 0.701 rs6138474 chr20:25012427 T/A cg26195577 chr20:24973756 C20orf3 0.76 9.4 0.45 7.94e-19 Blood protein levels; LIHC cis rs1577917 0.958 rs9647601 chr6:86449827 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.92 -0.31 7.64e-9 Response to antipsychotic treatment; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03647581 chr2:242660564 ING5 -0.42 -6.04 -0.31 4.11e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs782590 0.935 rs2586954 chr2:55892261 A/C cg18811423 chr2:55921094 PNPT1 0.9 14.1 0.61 6.38e-36 Metabolic syndrome; LIHC cis rs780096 0.527 rs11127044 chr2:27740404 C/G cg21747090 chr2:27597821 SNX17 -0.4 -5.82 -0.3 1.34e-8 Total body bone mineral density; LIHC cis rs7959452 0.718 rs10878963 chr12:69717166 T/G cg20891283 chr12:69753455 YEATS4 0.6 10.03 0.48 6.19e-21 Blood protein levels; LIHC cis rs17021463 0.676 rs11097421 chr4:95302915 T/C cg11021082 chr4:95130006 SMARCAD1 0.42 7.08 0.36 8.49e-12 Testicular germ cell tumor; LIHC cis rs4638749 0.677 rs6755598 chr2:108827674 G/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.71 -0.34 8.07e-11 Blood pressure; LIHC cis rs7091068 0.522 rs10882322 chr10:95483273 C/G cg20715218 chr10:95462985 C10orf4 0.52 5.97 0.31 6.1e-9 Urinary tract infection frequency; LIHC cis rs561341 0.883 rs72821942 chr17:30234460 C/T cg13647721 chr17:30228624 UTP6 0.8 7.65 0.38 2.07e-13 Hip circumference adjusted for BMI; LIHC cis rs1559088 0.649 rs4528686 chr19:33556074 A/G cg27124370 chr19:33622961 WDR88 0.47 7.09 0.36 7.77e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs17384381 0.861 rs12736004 chr1:85901367 G/A cg16011679 chr1:85725395 C1orf52 0.8 8.53 0.42 4.83e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs1983891 1.000 rs9381080 chr6:41527698 G/C cg20194872 chr6:41519635 FOXP4 0.43 6.81 0.35 4.32e-11 Prostate cancer; LIHC cis rs11871801 0.918 rs2006141 chr17:40679718 C/T cg14558262 chr17:40713999 COASY -0.52 -7.15 -0.36 5.23e-12 Crohn's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06522697 chr10:121356224 TIAL1 0.4 6.09 0.31 2.99e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs300890 0.520 rs713140 chr4:144317867 A/G cg21939631 chr18:11821960 GNAL -0.36 -6.27 -0.32 1.09e-9 Nasopharyngeal carcinoma; LIHC trans rs7618501 0.602 rs34831713 chr3:50118748 T/C cg21659725 chr3:3221576 CRBN -0.68 -10.84 -0.51 9.9899999999999993e-24 Intelligence (multi-trait analysis); LIHC trans rs800082 0.501 rs10935507 chr3:144214631 A/T cg24215973 chr2:240111563 HDAC4 0.45 6.34 0.32 7.26e-10 Smoking behavior; LIHC cis rs2153535 0.580 rs7742689 chr6:8452433 C/A cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC cis rs2073300 1.000 rs6132620 chr20:23436654 A/G cg12062639 chr20:23401060 NAPB 0.79 9.65 0.46 1.19e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8017423 0.935 rs17260827 chr14:90732703 G/A cg04374321 chr14:90722782 PSMC1 -0.78 -14.79 -0.62 1.31e-38 Mortality in heart failure; LIHC cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9640161 0.617 rs56019796 chr7:150009226 T/C cg17279839 chr7:150038598 RARRES2 0.49 10.08 0.48 4.39e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs2635047 0.967 rs2247784 chr18:44746997 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.44 5.72 0.3 2.27e-8 Educational attainment; LIHC cis rs57502260 0.573 rs11228294 chr11:68388567 C/T cg01657329 chr11:68192670 LRP5 -0.46 -5.78 -0.3 1.71e-8 Total body bone mineral density (age 45-60); LIHC cis rs11608355 0.515 rs2287192 chr12:109931594 C/T cg05360138 chr12:110035743 NA 0.94 10.72 0.5 2.65e-23 Neuroticism; LIHC cis rs1816752 0.746 rs9511270 chr13:25018680 C/T cg02811702 chr13:24901961 NA 0.25 6.42 0.33 4.48e-10 Obesity-related traits; LIHC cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg07061783 chr6:25882402 NA -0.47 -5.78 -0.3 1.71e-8 Intelligence (multi-trait analysis); LIHC cis rs1144333 1.000 rs75399471 chr1:76339092 A/T cg10523679 chr1:76189770 ACADM 0.45 6.01 0.31 4.88e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs4925386 1.000 rs6121990 chr20:60919263 G/A cg24112000 chr20:60950667 NA 0.45 7.02 0.36 1.17e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7249142 0.549 rs72997174 chr19:19294389 T/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.41 -6.89 -0.35 2.66e-11 IgG glycosylation; LIHC cis rs1034435 0.755 rs6007869 chr22:48894213 A/G cg05992904 chr22:48892994 FAM19A5 -0.52 -10.83 -0.51 1.06e-23 Late-onset Alzheimer's disease; LIHC cis rs4631830 0.720 rs11004415 chr10:51498181 G/A cg16070123 chr10:51489643 NA 0.37 5.9 0.3 8.68e-9 Prostate-specific antigen levels; LIHC cis rs2153535 0.580 rs1414340 chr6:8491139 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg21649660 chr6:10995125 ELOVL2 -0.33 -6.23 -0.32 1.41e-9 Pain; LIHC cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg16497277 chr3:49208875 KLHDC8B -0.5 -6.34 -0.32 7.07e-10 Menarche (age at onset); LIHC cis rs7429990 0.932 rs13085054 chr3:48134137 C/T cg11946769 chr3:48343235 NME6 -0.47 -6.22 -0.32 1.45e-9 Educational attainment (years of education); LIHC cis rs10540 0.730 rs61877766 chr11:512973 T/G cg03576123 chr11:487126 PTDSS2 -1.03 -7.25 -0.36 2.89e-12 Body mass index; LIHC cis rs8081395 0.801 rs2645479 chr17:57920532 A/G cg02344993 chr17:57696989 CLTC 0.46 7.61 0.38 2.69e-13 White blood cell count; LIHC cis rs12579753 0.869 rs12366921 chr12:82223024 G/A cg07988820 chr12:82153109 PPFIA2 -0.48 -5.84 -0.3 1.23e-8 Resting heart rate; LIHC cis rs6964587 0.900 rs6465352 chr7:91775117 A/G cg17063962 chr7:91808500 NA 1.06 22.62 0.77 6.65e-70 Breast cancer; LIHC cis rs7772486 0.754 rs9399567 chr6:146147295 C/T cg23711669 chr6:146136114 FBXO30 0.74 13.51 0.59 1.27e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs4654899 1.000 rs6426660 chr1:21361640 A/G cg08539965 chr1:21396338 EIF4G3 0.33 5.74 0.3 2.07e-8 Superior frontal gyrus grey matter volume; LIHC cis rs11764590 0.666 rs3996325 chr7:2053747 T/C cg23043544 chr7:2124092 MAD1L1 -0.51 -8.22 -0.41 4.2e-15 Neuroticism; LIHC cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg10217327 chr6:118973057 C6orf204 0.64 6.22 0.32 1.48e-9 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05886006 chr1:161359784 NA 0.49 7.49 0.38 5.75e-13 Pancreatic cancer; LIHC cis rs11671005 0.779 rs3794971 chr19:58985866 T/C cg25952890 chr19:58913133 NA 0.72 7.38 0.37 1.17e-12 Mean platelet volume; LIHC cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg03060546 chr3:49711283 APEH 0.4 5.86 0.3 1.11e-8 Menarche (age at onset); LIHC cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg04772025 chr11:68637568 NA 0.46 5.84 0.3 1.18e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2803122 0.502 rs1329731 chr9:19234908 C/T cg13469590 chr9:19229767 NA -0.37 -6.4 -0.33 5.05e-10 Pulse pressure; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01868382 chr3:182698721 DCUN1D1 0.4 6.17 0.32 1.91e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs6467710 0.744 rs28653652 chr7:137204683 A/T cg04467748 chr15:79760772 KIAA1024 0.44 6.47 0.33 3.32e-10 AIDS progression; LIHC cis rs7116495 0.609 rs6592457 chr11:71738086 G/C cg26138937 chr11:71823887 C11orf51 -1.31 -10.43 -0.49 2.7e-22 Severe influenza A (H1N1) infection; LIHC cis rs5753037 0.702 rs140143 chr22:30173109 G/T cg01021169 chr22:30184971 ASCC2 -0.35 -6.59 -0.34 1.69e-10 Type 1 diabetes; LIHC cis rs7647973 1.000 rs7644148 chr3:49545241 G/A cg07636037 chr3:49044803 WDR6 -0.54 -6.66 -0.34 1.09e-10 Menarche (age at onset); LIHC cis rs7089973 0.604 rs10490909 chr10:116593532 C/T cg23260525 chr10:116636907 FAM160B1 0.35 7.12 0.36 6.56e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7116495 0.609 rs2735787 chr11:71717873 T/C cg10381502 chr11:71823885 C11orf51 -1.06 -9.3 -0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08165151 chr6:88411075 NCRNA00120;AKIRIN2 0.47 6.23 0.32 1.41e-9 Pancreatic cancer; LIHC cis rs4718428 0.705 rs4717328 chr7:66352665 T/C cg12165864 chr7:66369176 NA -0.47 -6.82 -0.35 4.17e-11 Corneal structure; LIHC cis rs7487075 0.619 rs10880973 chr12:46853209 C/A cg23829395 chr12:46796953 NA 0.33 5.82 0.3 1.33e-8 Itch intensity from mosquito bite; LIHC cis rs5769765 1.000 rs8138941 chr22:50290678 G/A cg26441486 chr22:50317300 CRELD2 0.35 6.33 0.32 7.65e-10 Schizophrenia; LIHC cis rs11577318 0.853 rs12728971 chr1:26626612 C/T cg10402321 chr1:26617780 UBXN11 -0.38 -5.8 -0.3 1.48e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs12477438 0.501 rs2632260 chr2:99771590 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs6448317 1.000 rs13105803 chr4:24940002 A/G cg21108841 chr4:24914750 CCDC149 -0.47 -6.0 -0.31 5e-9 Heschl's gyrus morphology; LIHC cis rs6952808 0.792 rs11771973 chr7:1950440 C/G cg20295408 chr7:1910781 MAD1L1 -0.51 -7.36 -0.37 1.39e-12 Bipolar disorder and schizophrenia; LIHC cis rs11608355 0.515 rs11609921 chr12:109918405 A/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs1008375 1.000 rs10805359 chr4:17684886 A/G cg02297831 chr4:17616191 MED28 0.43 6.83 0.35 3.9e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7582720 1.000 rs7560547 chr2:203757916 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs8062405 0.558 rs151228 chr16:28563026 A/G cg00204512 chr16:28754710 NA 0.3 6.0 0.31 5.06e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs11098499 0.722 rs7673476 chr4:120248683 C/T cg25214090 chr10:38739885 LOC399744 0.49 8.08 0.4 1.16e-14 Corneal astigmatism; LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg23601095 chr6:26197514 HIST1H3D 0.55 5.83 0.3 1.27e-8 Gout;Renal underexcretion gout; LIHC cis rs7953249 0.618 rs2650000 chr12:121388962 G/T cg02403541 chr12:121454288 C12orf43 0.42 7.48 0.37 6.3e-13 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs7582720 1.000 rs72932791 chr2:203700870 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 5.99 0.31 5.39e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6964587 1.000 rs12666179 chr7:91574110 T/C cg17063962 chr7:91808500 NA -1.03 -20.55 -0.74 1.15e-61 Breast cancer; LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs7572733 0.534 rs700682 chr2:198712310 C/A cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs35892873 0.959 rs9877710 chr3:126091223 A/G cg15490784 chr3:126061950 KLF15 0.45 6.51 0.33 2.68e-10 Male-pattern baldness; LIHC cis rs6951245 0.935 rs79067319 chr7:1065548 C/T cg24642844 chr7:1081250 C7orf50 -0.89 -8.94 -0.44 2.52e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg15691649 chr6:25882328 NA -0.91 -11.35 -0.52 1.44e-25 Intelligence (multi-trait analysis); LIHC cis rs921968 0.565 rs6704575 chr2:219589594 C/T cg02985541 chr2:219472218 PLCD4 0.36 6.31 0.32 8.61e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs3008870 1.000 rs2985825 chr1:67412822 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs2070488 1.000 rs6772046 chr3:38479660 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.94 16.08 0.66 1.01e-43 Electrocardiographic conduction measures; LIHC cis rs818427 0.964 rs351767 chr5:112200098 A/G cg07820702 chr5:112228657 REEP5 0.36 5.75 0.3 1.95e-8 Total body bone mineral density; LIHC cis rs12980942 1.000 rs1865053 chr19:41814412 T/C cg25627403 chr19:41769009 HNRNPUL1 0.5 6.18 0.32 1.81e-9 Coronary artery disease; LIHC cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs17253792 0.822 rs58569951 chr14:56152245 T/C cg01858014 chr14:56050164 KTN1 -0.66 -7.61 -0.38 2.62e-13 Putamen volume; LIHC trans rs877282 0.583 rs12356155 chr10:823940 C/T cg22713356 chr15:30763199 NA 0.83 7.29 0.37 2.12e-12 Uric acid levels; LIHC cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg00166722 chr3:10149974 C3orf24 0.51 5.84 0.3 1.23e-8 Alzheimer's disease; LIHC cis rs2073300 1.000 rs6036422 chr20:23456962 A/T cg12062639 chr20:23401060 NAPB 0.77 9.63 0.46 1.36e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9318086 0.648 rs9510927 chr13:24467641 T/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.56 10.88 0.51 7.15e-24 Myopia (pathological); LIHC cis rs10088262 0.629 rs7828192 chr8:124804669 C/T cg02993010 chr8:124780839 FAM91A1 -0.46 -6.01 -0.31 4.77e-9 Pancreatic cancer; LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg03721293 chr16:90014378 DEF8 0.42 7.0 0.35 1.33e-11 Skin colour saturation; LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg26338869 chr17:61819248 STRADA 0.53 7.17 0.36 4.79e-12 Height; LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg10774155 chr7:65338427 VKORC1L1 0.44 6.49 0.33 3.05e-10 Calcium levels; LIHC cis rs7772486 0.846 rs866473 chr6:146353414 A/C cg23711669 chr6:146136114 FBXO30 0.66 11.79 0.54 3.69e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs920590 1.000 rs920590 chr8:19651161 A/G cg03894339 chr8:19674705 INTS10 0.42 6.25 0.32 1.22e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.35 0.8 1.14e-76 Prudent dietary pattern; LIHC cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.81 0.3 1.42e-8 Menopause (age at onset); LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg18306943 chr3:40428807 ENTPD3 0.43 7.51 0.38 5.27e-13 Renal cell carcinoma; LIHC cis rs9549367 0.789 rs7317558 chr13:113893625 G/A cg00898013 chr13:113819073 PROZ -0.36 -6.45 -0.33 3.85e-10 Platelet distribution width; LIHC cis rs1348850 0.757 rs4893969 chr2:178478476 T/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.65 8.87 0.43 4.28e-17 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2380220 0.808 rs2613553 chr6:95916704 A/G cg04719120 chr6:96025338 MANEA -0.58 -6.24 -0.32 1.33e-9 Behavioural disinhibition (generation interaction); LIHC cis rs2070433 0.800 rs11702190 chr21:47877367 C/T cg12379764 chr21:47803548 PCNT 0.71 10.07 0.48 4.8e-21 Lymphocyte counts; LIHC cis rs10493773 0.928 rs12751296 chr1:86176968 G/A cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.45 -0.37 7.71e-13 Urate levels in overweight individuals; LIHC cis rs7635838 0.503 rs9853547 chr3:11396101 C/G cg00170343 chr3:11313890 ATG7 0.49 7.73 0.39 1.19e-13 HDL cholesterol; LIHC cis rs1348850 0.651 rs4893821 chr2:178229352 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.8 -12.42 -0.56 1.75e-29 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg23283495 chr1:209979779 IRF6 0.44 7.21 0.36 3.56e-12 Cleft lip with or without cleft palate; LIHC cis rs7937682 0.681 rs2156580 chr11:111394328 C/G cg09085632 chr11:111637200 PPP2R1B 0.46 6.02 0.31 4.61e-9 Primary sclerosing cholangitis; LIHC cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg02951883 chr7:2050386 MAD1L1 -0.62 -9.52 -0.46 3.21e-19 Bipolar disorder and schizophrenia; LIHC cis rs7487075 0.606 rs4768714 chr12:46814245 T/A cg23829395 chr12:46796953 NA 0.35 6.26 0.32 1.16e-9 Itch intensity from mosquito bite; LIHC cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg10295955 chr4:187884368 NA -0.96 -22.01 -0.77 1.75e-67 Lobe attachment (rater-scored or self-reported); LIHC cis rs16828019 0.929 rs35286837 chr1:41682998 T/G cg03387723 chr1:41708464 SCMH1 -0.44 -7.23 -0.36 3.16e-12 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg17372223 chr3:52568218 NT5DC2 0.36 5.97 0.31 5.98e-9 Bipolar disorder; LIHC cis rs735396 1.000 rs2464195 chr12:121435475 G/A cg02403541 chr12:121454288 C12orf43 0.46 8.12 0.4 8.52e-15 N-glycan levels; LIHC cis rs12960505 0.506 rs1910132 chr18:51000262 C/T cg24270629 chr18:50823537 DCC -0.43 -6.07 -0.31 3.34e-9 Intelligence (multi-trait analysis); LIHC cis rs9389248 0.690 rs6569982 chr6:135256495 C/G cg24558204 chr6:135376177 HBS1L 0.6 9.92 0.47 1.47e-20 High light scatter reticulocyte percentage of red cells; LIHC cis rs7208859 0.673 rs11649765 chr17:29233888 T/A cg13385521 chr17:29058706 SUZ12P 0.84 8.15 0.4 7.08e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17270561 0.562 rs74293932 chr6:26014811 C/A cg17691542 chr6:26056736 HIST1H1C 1.02 12.88 0.57 3.34e-31 Iron status biomarkers; LIHC cis rs1371867 0.875 rs1660320 chr8:101337579 A/C cg06636551 chr8:101224915 SPAG1 -0.47 -8.38 -0.41 1.35e-15 Atrioventricular conduction; LIHC cis rs10426930 0.738 rs2620815 chr19:5051840 C/G cg18473234 chr19:5097819 KDM4B -0.49 -6.22 -0.32 1.45e-9 Monocyte percentage of white cells; LIHC trans rs8002861 0.967 rs9525871 chr13:44477712 A/T cg17145862 chr1:211918768 LPGAT1 0.66 13.29 0.58 9.02e-33 Leprosy; LIHC cis rs6545883 0.894 rs2177962 chr2:61588070 T/A cg15711740 chr2:61764176 XPO1 0.42 5.74 0.3 2.1e-8 Tuberculosis; LIHC cis rs4819052 0.851 rs2838832 chr21:46664904 A/G cg11663144 chr21:46675770 NA 0.35 6.53 0.33 2.44e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg00475322 chr7:917719 C7orf20 0.42 7.19 0.36 4.22e-12 Perceived unattractiveness to mosquitoes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11792281 chr17:26443366 NLK -0.41 -6.12 -0.31 2.6e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11711311 0.911 rs28577577 chr3:113447276 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.41 0.45 7.27e-19 IgG glycosylation; LIHC cis rs2576037 0.583 rs616900 chr18:44410849 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.71 11.16 0.52 7.26e-25 Personality dimensions; LIHC cis rs847649 0.699 rs7794668 chr7:102510416 C/T cg18108683 chr7:102477205 FBXL13 0.49 7.61 0.38 2.67e-13 Morning vs. evening chronotype; LIHC trans rs208520 0.690 rs10455594 chr6:66737894 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.93 0.43 2.63e-17 Exhaled nitric oxide output; LIHC cis rs918629 0.530 rs13361837 chr5:95250478 T/G cg10483112 chr5:95245456 ELL2 -0.39 -7.18 -0.36 4.42e-12 IgG glycosylation; LIHC cis rs7119038 0.865 rs7951740 chr11:118740418 G/C cg19308663 chr11:118741387 NA -0.46 -6.04 -0.31 4.1e-9 Sjögren's syndrome; LIHC cis rs13191362 1.000 rs13201023 chr6:162981381 C/G cg21926612 chr6:163149169 PACRG;PARK2 0.65 5.79 0.3 1.6e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs17253792 0.749 rs17747301 chr14:56125030 C/G cg01858014 chr14:56050164 KTN1 -0.71 -7.22 -0.36 3.38e-12 Putamen volume; LIHC cis rs11628318 0.564 rs8013957 chr14:103140254 C/T cg12046867 chr14:103022105 NA 0.43 6.69 0.34 9.34e-11 Platelet count; LIHC cis rs6964587 0.773 rs62467797 chr7:91889722 G/A cg17063962 chr7:91808500 NA 0.98 16.85 0.67 7.96e-47 Breast cancer; LIHC cis rs13118159 0.934 rs4974608 chr4:1356780 C/T cg16405210 chr4:1374714 KIAA1530 -0.59 -7.43 -0.37 9.04e-13 Longevity; LIHC cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs908922 0.542 rs4845785 chr1:152510143 C/T cg20991723 chr1:152506922 NA 0.59 10.62 0.5 5.87e-23 Hair morphology; LIHC cis rs2115630 0.967 rs8028490 chr15:85277888 G/A cg11189052 chr15:85197271 WDR73 -0.39 -5.87 -0.3 1.03e-8 P wave terminal force; LIHC trans rs61931739 0.500 rs7484658 chr12:34515879 A/G cg26384229 chr12:38710491 ALG10B 0.63 8.12 0.4 8.29e-15 Morning vs. evening chronotype; LIHC cis rs9296092 0.538 rs9296094 chr6:33520064 A/G cg13560919 chr6:33536144 NA -0.39 -6.31 -0.32 8.5e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs926937 0.843 rs5752577 chr22:27930781 A/G cg19819135 chr1:70710422 SFRS11 -0.78 -6.12 -0.31 2.51e-9 Age-related cataracts; LIHC cis rs2645694 0.626 rs2703122 chr4:77821418 A/C cg03477792 chr4:77819574 ANKRD56 0.61 8.86 0.43 4.39e-17 Emphysema distribution in smoking; LIHC trans rs35110281 0.574 rs1836856 chr21:44964638 A/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.65 0.34 1.16e-10 Mean corpuscular volume; LIHC cis rs72843506 0.586 rs75836592 chr17:19838352 A/C cg12065943 chr17:19881925 AKAP10 -0.39 -6.53 -0.33 2.32e-10 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08079518 chr17:73775869 H3F3B 0.49 7.1 0.36 7.13e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs1003719 0.715 rs2835675 chr21:38582815 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.53 -0.49 1.22e-22 Eye color traits; LIHC cis rs7208859 0.524 rs60114476 chr17:29097667 A/T cg13385521 chr17:29058706 SUZ12P 0.83 8.16 0.4 6.26e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6582630 0.519 rs11495376 chr12:38284957 A/C cg26384229 chr12:38710491 ALG10B 0.59 8.1 0.4 9.89e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs9910055 0.550 rs113844752 chr17:42297631 C/A cg08499158 chr17:42289980 UBTF -0.5 -8.55 -0.42 4.12e-16 Total body bone mineral density; LIHC cis rs2071426 0.652 rs11188127 chr10:96761891 A/G cg09036531 chr10:96991505 NA -0.51 -6.06 -0.31 3.62e-9 Blood metabolite levels; LIHC cis rs769267 0.895 rs2965189 chr19:19519518 G/T cg03709012 chr19:19516395 GATAD2A 0.99 17.46 0.69 2.81e-49 Tonsillectomy; LIHC cis rs7131987 0.934 rs2216854 chr12:29423460 G/A cg16970926 chr12:29381810 FAR2 0.31 6.58 0.34 1.79e-10 QT interval; LIHC cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.9 -10.39 -0.49 3.83e-22 Platelet count; LIHC cis rs6840360 0.718 rs2136960 chr4:152746189 A/G cg22705602 chr4:152727874 NA 0.28 5.78 0.3 1.65e-8 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.913 rs11228287 chr11:68349754 A/G cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.94e-14 Total body bone mineral density; LIHC cis rs7224685 0.859 rs34348519 chr17:4094140 G/C cg09695851 chr17:3907499 NA 0.59 7.82 0.39 6.68e-14 Type 2 diabetes; LIHC cis rs7312933 0.585 rs7969814 chr12:42669657 C/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 7.96 0.4 2.53e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs77633900 0.772 rs283796 chr15:76774105 G/A cg21673338 chr15:77095150 SCAPER -0.52 -5.82 -0.3 1.33e-8 Non-glioblastoma glioma;Glioma; LIHC cis rs8180040 1.000 rs2159400 chr3:47375890 T/C cg16586182 chr3:47516702 SCAP 0.57 10.5 0.49 1.53e-22 Colorectal cancer; LIHC cis rs7312774 0.748 rs1861745 chr12:107301642 C/T cg16260113 chr12:107380972 MTERFD3 0.83 11.05 0.51 1.8e-24 Severe influenza A (H1N1) infection; LIHC cis rs5769707 0.749 rs8137251 chr22:50036669 G/A cg07959070 chr22:50026188 C22orf34 -0.34 -8.67 -0.42 1.75e-16 Monocyte count;Monocyte percentage of white cells; LIHC trans rs11098499 0.754 rs878376 chr4:120237702 G/A cg25214090 chr10:38739885 LOC399744 0.53 8.72 0.43 1.25e-16 Corneal astigmatism; LIHC cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.84 8.7 0.43 1.45e-16 Platelet count; LIHC cis rs2637266 0.875 rs12783253 chr10:78378108 A/G cg18941641 chr10:78392320 NA 0.29 6.09 0.31 3.1e-9 Pulmonary function; LIHC cis rs875971 0.789 rs7808013 chr7:66071196 A/G cg11764359 chr7:65958608 NA -0.78 -13.64 -0.59 4.13e-34 Aortic root size; LIHC cis rs754466 0.914 rs4595491 chr10:79685833 G/A cg17075019 chr10:79541650 NA -0.61 -8.14 -0.4 7.42e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.42 -0.41 1.04e-15 Lymphocyte counts; LIHC cis rs4555082 0.645 rs2816605 chr14:105715515 C/T cg10792982 chr14:105748885 BRF1 0.51 6.61 0.34 1.5e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs6502050 0.835 rs4789731 chr17:80145904 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.92 -0.31 7.68e-9 Life satisfaction; LIHC cis rs6752107 0.935 rs11688431 chr2:234147175 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.47 7.0 0.35 1.33e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4332037 0.950 rs56403963 chr7:1946130 C/G cg23422044 chr7:1970798 MAD1L1 -0.64 -7.31 -0.37 1.95e-12 Bipolar disorder; LIHC cis rs17685 0.725 rs7807647 chr7:75628669 G/A cg16684958 chr7:75615977 POR -0.5 -8.45 -0.42 8.7e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg05484376 chr2:27715224 FNDC4 0.39 6.65 0.34 1.14e-10 Total body bone mineral density; LIHC cis rs11971779 0.618 rs9640925 chr7:139085288 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs918629 0.761 rs3777165 chr5:95291425 A/G cg10483112 chr5:95245456 ELL2 0.36 6.18 0.32 1.85e-9 IgG glycosylation; LIHC cis rs1023500 0.596 rs5751204 chr22:42433801 C/T cg04733989 chr22:42467013 NAGA 0.65 9.16 0.44 5.03e-18 Schizophrenia; LIHC cis rs6088590 0.813 rs1884668 chr20:33285514 A/G cg24642439 chr20:33292090 TP53INP2 0.51 7.18 0.36 4.41e-12 Coronary artery disease; LIHC cis rs1707322 0.721 rs4415615 chr1:46132109 C/T cg03146154 chr1:46216737 IPP 0.57 9.89 0.47 1.96e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1018836 0.923 rs10956720 chr8:91576222 C/T cg16814680 chr8:91681699 NA -0.66 -10.62 -0.5 5.95e-23 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs769267 0.965 rs2074550 chr19:19387743 A/C cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC trans rs61931739 0.534 rs10844725 chr12:34009504 C/A cg26384229 chr12:38710491 ALG10B 0.51 7.14 0.36 5.65e-12 Morning vs. evening chronotype; LIHC cis rs9911578 1.000 rs8079774 chr17:56908188 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.85 -0.43 4.75e-17 Intelligence (multi-trait analysis); LIHC cis rs9828933 0.832 rs3774723 chr3:63962339 G/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.75 -9.64 -0.46 1.32e-19 Type 2 diabetes; LIHC cis rs929354 0.742 rs7801905 chr7:156940111 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg25894440 chr7:65020034 NA 0.53 6.15 0.32 2.16e-9 Diabetic kidney disease; LIHC cis rs10504229 0.834 rs7015674 chr8:58153166 C/T cg02290350 chr8:58132656 NA 0.37 8.07 0.4 1.22e-14 Developmental language disorder (linguistic errors); LIHC cis rs3106136 0.843 rs901615 chr4:95228687 A/C cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.5 -0.38 5.59e-13 Capecitabine sensitivity; LIHC cis rs798554 0.660 rs2644296 chr7:2859061 A/T cg13628971 chr7:2884303 GNA12 0.42 6.76 0.34 6.04e-11 Height; LIHC cis rs10771431 0.597 rs7976807 chr12:9352459 G/A cg08997352 chr12:9597637 DDX12 -0.49 -7.61 -0.38 2.64e-13 Breast size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15731816 chr14:75230414 YLPM1 0.39 6.39 0.33 5.5e-10 Pancreatic cancer; LIHC trans rs1005277 0.579 rs2505248 chr10:38459097 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.19 -0.52 5.65e-25 Extrinsic epigenetic age acceleration; LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg17178900 chr1:205818956 PM20D1 -0.63 -9.37 -0.45 1.04e-18 Menarche (age at onset); LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg21747090 chr2:27597821 SNX17 -0.44 -6.69 -0.34 9.07e-11 Total body bone mineral density; LIHC cis rs2153535 0.601 rs9505474 chr6:8539794 C/G cg23788917 chr6:8435910 SLC35B3 0.62 8.66 0.42 1.89e-16 Motion sickness; LIHC cis rs7131987 0.650 rs67146951 chr12:29450553 C/A cg21522988 chr12:29376872 FAR2 0.26 5.83 0.3 1.29e-8 QT interval; LIHC trans rs6951245 0.744 rs10265758 chr7:1172518 C/T cg13565492 chr6:43139072 SRF -0.76 -6.57 -0.33 1.87e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7937682 0.924 rs10891284 chr11:111527737 T/C cg09085632 chr11:111637200 PPP2R1B -1.04 -13.22 -0.58 1.56e-32 Primary sclerosing cholangitis; LIHC cis rs7615952 0.515 rs7630575 chr3:125682330 A/G cg05084668 chr3:125655381 ALG1L -0.55 -8.64 -0.42 2.2e-16 Blood pressure (smoking interaction); LIHC trans rs6461049 0.800 rs2398706 chr7:2156338 A/T cg04565464 chr8:145669602 NFKBIL2 0.39 6.48 0.33 3.19e-10 Schizophrenia; LIHC trans rs60843830 1.000 rs7566279 chr2:281178 C/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.46 0.46 5.21e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs1997103 1.000 rs4628219 chr7:55410449 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC trans rs2262909 0.962 rs409439 chr19:22227432 C/T cg05197062 chr11:11642011 GALNTL4 -0.42 -6.11 -0.31 2.73e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg02782426 chr3:40428986 ENTPD3 0.33 6.02 0.31 4.5e-9 Renal cell carcinoma; LIHC cis rs1494950 1.000 rs77326179 chr4:15024940 A/G cg12377275 chr4:15005593 CPEB2 -0.85 -7.41 -0.37 9.71e-13 Political ideology; LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg27432699 chr2:27873401 GPN1 -0.49 -7.13 -0.36 6e-12 Total body bone mineral density; LIHC cis rs7584330 0.666 rs72620817 chr2:238353661 C/T cg14458575 chr2:238380390 NA 0.53 7.46 0.37 7.18e-13 Prostate cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03332314 chr8:146278003 C8orf33 0.5 6.49 0.33 3.01e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs780096 0.546 rs2293571 chr2:27729480 C/T cg05484376 chr2:27715224 FNDC4 0.38 6.53 0.33 2.44e-10 Total body bone mineral density; LIHC cis rs8017423 0.933 rs7150378 chr14:90724566 G/A cg14092571 chr14:90743983 NA -0.39 -6.21 -0.32 1.5e-9 Mortality in heart failure; LIHC trans rs9951602 0.512 rs8097996 chr18:76648035 A/G cg02800362 chr5:177631904 HNRNPAB 0.67 10.48 0.49 1.76e-22 Obesity-related traits; LIHC trans rs208520 0.802 rs4710314 chr6:66883656 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.14 -0.4 7.54e-15 Exhaled nitric oxide output; LIHC cis rs4819052 0.851 rs1056099 chr21:46678892 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.8 0.5 1.4e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7103648 0.695 rs7933019 chr11:47509137 G/C cg20307385 chr11:47447363 PSMC3 1.02 16.69 0.67 3.68e-46 Diastolic blood pressure;Systolic blood pressure; LIHC trans rs877282 0.797 rs11253329 chr10:753200 A/T cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs10411936 0.692 rs62118141 chr19:16602808 T/C cg10248733 chr19:16607483 C19orf44;CALR3 0.5 6.73 0.34 7.31e-11 White blood cell count;Multiple sclerosis; LIHC cis rs67311347 0.956 rs12633446 chr3:40505661 G/A cg18306943 chr3:40428807 ENTPD3 -0.37 -6.5 -0.33 2.83e-10 Renal cell carcinoma; LIHC cis rs7769051 1.000 rs6910639 chr6:133120553 A/G cg22852734 chr6:133119734 C6orf192 0.97 9.55 0.46 2.5e-19 Type 2 diabetes nephropathy; LIHC cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg13047869 chr3:10149882 C3orf24 0.5 6.43 0.33 4.4e-10 Alzheimer's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25236837 chr7:65959120 NA -0.47 -6.21 -0.32 1.57e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg18404041 chr3:52824283 ITIH1 -0.43 -6.98 -0.35 1.51e-11 Electroencephalogram traits; LIHC cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg24549020 chr5:56110836 MAP3K1 0.52 6.77 0.34 5.67e-11 Initial pursuit acceleration; LIHC cis rs11786130 0.901 rs4733817 chr8:129005584 G/A cg01765152 chr8:129005526 PVT1 -0.29 -6.28 -0.32 1.03e-9 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs10791097 0.748 rs4937580 chr11:130734270 T/C cg22079354 chr11:130786696 SNX19 0.41 6.02 0.31 4.39e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg21314978 chr2:96191015 NA 0.43 6.32 0.32 8.01e-10 Immature fraction of reticulocytes; LIHC cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.47 0.33 3.39e-10 Mean platelet volume; LIHC trans rs3780486 0.505 rs10758188 chr9:33123386 C/T cg04842962 chr6:43655489 MRPS18A -0.9 -19.03 -0.72 1.35e-55 IgG glycosylation; LIHC cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg16325326 chr1:53192061 ZYG11B 0.42 6.92 0.35 2.31e-11 Monocyte count; LIHC cis rs801193 0.548 rs2659904 chr7:66178602 C/A cg18876405 chr7:65276391 NA 0.33 5.92 0.31 7.7e-9 Aortic root size; LIHC cis rs4144743 1.000 rs34492688 chr17:45321622 C/A cg18085866 chr17:45331354 ITGB3 -0.57 -8.32 -0.41 2.14e-15 Body mass index; LIHC cis rs11605275 1.000 rs11605704 chr11:20032096 A/G cg14835545 chr11:20032148 NAV2 0.8 7.41 0.37 1.02e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9818758 0.545 rs11717978 chr3:48969036 T/A cg00383909 chr3:49044727 WDR6 0.96 7.95 0.4 2.65e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2404602 0.967 rs7167613 chr15:77041192 C/A cg23625390 chr15:77176239 SCAPER 0.42 6.98 0.35 1.54e-11 Blood metabolite levels; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg26338869 chr17:61819248 STRADA 0.58 8.58 0.42 3.28e-16 Prudent dietary pattern; LIHC cis rs28489187 0.706 rs3087894 chr1:85787118 G/C cg16011679 chr1:85725395 C1orf52 0.48 6.14 0.31 2.35e-9 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs1801251 1.000 rs4517962 chr2:233578337 T/C cg08000102 chr2:233561755 GIGYF2 0.75 11.35 0.52 1.54e-25 Coronary artery disease; LIHC cis rs4319547 0.695 rs4758645 chr12:122946487 G/A cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.32 -0.41 2.16e-15 Body mass index; LIHC cis rs735396 0.770 rs1169314 chr12:121443116 A/G cg25281562 chr12:121454272 C12orf43 0.36 6.17 0.32 1.91e-9 N-glycan levels; LIHC cis rs2842992 0.830 rs1535475 chr6:160148935 T/C cg19482086 chr6:160211437 TCP1;MRPL18 0.71 12.46 0.56 1.21e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs611744 0.647 rs7015240 chr8:109262204 G/A cg18478394 chr8:109455254 TTC35 0.39 6.81 0.35 4.49e-11 Dupuytren's disease; LIHC cis rs17685 0.725 rs1044483 chr7:75659815 T/C cg16684958 chr7:75615977 POR -0.49 -8.3 -0.41 2.38e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7552404 0.727 rs1144336 chr1:76277421 C/A cg03433033 chr1:76189801 ACADM 0.55 6.9 0.35 2.5e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7613875 0.620 rs13079006 chr3:49996924 G/T cg24110177 chr3:50126178 RBM5 -0.53 -8.64 -0.42 2.17e-16 Body mass index; LIHC trans rs11098499 0.908 rs9995234 chr4:120321827 A/G cg25214090 chr10:38739885 LOC399744 0.6 9.55 0.46 2.51e-19 Corneal astigmatism; LIHC cis rs743757 1.000 rs2236954 chr3:50425177 C/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.53 8.18 0.4 5.59e-15 Diastolic blood pressure; LIHC cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7432375 0.901 rs35874192 chr3:136470004 G/C cg21827317 chr3:136751795 NA -0.44 -5.75 -0.3 2.01e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs769267 0.895 rs2916073 chr19:19528324 T/G cg15052019 chr19:19431593 KIAA0892;SF4 0.42 5.83 0.3 1.27e-8 Tonsillectomy; LIHC cis rs4595586 0.525 rs1878227 chr12:39355719 A/T cg26384229 chr12:38710491 ALG10B 0.53 6.34 0.32 7.3e-10 Morning vs. evening chronotype; LIHC cis rs1075232 0.826 rs4779556 chr15:32173245 T/C cg01030201 chr15:31746330 NA 0.78 6.22 0.32 1.42e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs2153535 0.601 rs7738877 chr6:8542230 A/G cg23788917 chr6:8435910 SLC35B3 0.61 9.04 0.44 1.16e-17 Motion sickness; LIHC cis rs4790333 0.562 rs2447108 chr17:2257993 C/T cg02569219 chr17:2266849 SGSM2 0.42 6.41 0.33 4.97e-10 Proinsulin levels; LIHC cis rs7309 0.935 rs1921309 chr2:162048975 T/A cg21211367 chr2:162094118 NA 0.37 5.73 0.3 2.25e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.59 -8.53 -0.42 4.85e-16 Lymphocyte counts; LIHC cis rs7089973 0.585 rs7907837 chr10:116610690 G/T cg03647239 chr10:116582469 FAM160B1 0.46 6.77 0.34 5.47e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs950169 0.922 rs11635505 chr15:85097034 A/C cg03959625 chr15:84868606 LOC388152 -0.48 -6.96 -0.35 1.71e-11 Schizophrenia; LIHC cis rs10170846 1.000 rs10170846 chr2:223517705 C/G cg25565276 chr2:223520875 FARSB -0.7 -10.57 -0.5 8.56e-23 Schizophrenia (inflammation and infection response interaction); LIHC trans rs11098499 0.865 rs28634456 chr4:120375778 A/G cg25214090 chr10:38739885 LOC399744 0.62 9.85 0.47 2.67e-20 Corneal astigmatism; LIHC trans rs1814175 0.781 rs11040681 chr11:49981654 G/T cg03929089 chr4:120376271 NA -0.89 -18.22 -0.7 2.49e-52 Height; LIHC cis rs2455799 0.613 rs10510443 chr3:15829127 A/G cg12698662 chr3:15914712 MIR563 -0.39 -7.44 -0.37 8.16e-13 Mean platelet volume; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg09367891 chr1:107599246 PRMT6 -0.73 -12.02 -0.54 5.37e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6542838 0.702 rs6739176 chr2:99536846 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.86 -0.35 3.22e-11 Fear of minor pain; LIHC trans rs4907240 0.883 rs11678174 chr2:97249103 T/C cg26665480 chr2:98280029 ACTR1B -0.41 -6.17 -0.32 1.88e-9 Event-related brain oscillations; LIHC cis rs523522 0.885 rs524735 chr12:121022099 T/C cg27279351 chr12:120934652 DYNLL1 0.68 11.96 0.54 8.87e-28 High light scatter reticulocyte count; LIHC cis rs9549367 0.789 rs9577218 chr13:113894911 A/G cg18105134 chr13:113819100 PROZ -0.57 -10.23 -0.48 1.3e-21 Platelet distribution width; LIHC cis rs769267 0.965 rs4808938 chr19:19401218 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.14e-9 Tonsillectomy; LIHC cis rs7914558 0.752 rs7896519 chr10:104866863 C/T cg15744005 chr10:104629667 AS3MT -0.42 -9.58 -0.46 2.07e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9905704 0.647 rs12940492 chr17:56954655 C/G cg12560992 chr17:57184187 TRIM37 0.68 9.93 0.47 1.36e-20 Testicular germ cell tumor; LIHC cis rs796364 0.760 rs74993507 chr2:201068684 C/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.68 -7.25 -0.36 2.84e-12 Schizophrenia; LIHC cis rs10791323 0.569 rs10750553 chr11:133740251 T/C cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.53e-9 Childhood ear infection; LIHC cis rs4638749 0.677 rs10185601 chr2:108828278 A/G cg06795125 chr2:108905320 SULT1C2 -0.29 -5.75 -0.3 1.94e-8 Blood pressure; LIHC cis rs9300255 0.602 rs949142 chr12:123634043 T/C cg00376283 chr12:123451042 ABCB9 0.59 6.71 0.34 8.15e-11 Neutrophil percentage of white cells; LIHC cis rs7520050 0.966 rs61783220 chr1:46335312 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs3540 0.553 rs2158406 chr15:90994499 T/C cg22089800 chr15:90895588 ZNF774 0.57 7.87 0.39 4.59e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs8072100 1.000 rs4794048 chr17:45763073 A/C cg08085267 chr17:45401833 C17orf57 -0.55 -8.23 -0.41 3.96e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10876993 0.826 rs1678534 chr12:58057435 A/C cg04478727 chr12:58166393 METTL1;FAM119B -0.47 -6.69 -0.34 8.99e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs10883723 0.775 rs7917158 chr10:104246471 C/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.08 0.58 5.63e-32 Allergic disease (asthma, hay fever or eczema); LIHC trans rs2749592 0.611 rs2505199 chr10:38392457 G/A cg17830980 chr10:43048298 ZNF37B -0.43 -7.73 -0.39 1.17e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7647973 0.506 rs11920251 chr3:49356671 C/T cg03060546 chr3:49711283 APEH 0.42 6.48 0.33 3.25e-10 Menarche (age at onset); LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg07677032 chr17:61819896 STRADA 0.44 6.44 0.33 4.01e-10 Prudent dietary pattern; LIHC cis rs9399135 0.967 rs2183709 chr6:135377091 C/T cg24558204 chr6:135376177 HBS1L 0.44 7.22 0.36 3.5e-12 Red blood cell count; LIHC cis rs1728785 1.000 rs1645928 chr16:68590610 G/T cg02972257 chr16:68554789 NA -0.55 -6.17 -0.32 1.96e-9 Ulcerative colitis; LIHC cis rs4808199 0.948 rs757000 chr19:19448301 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.56 8.12 0.4 8.8e-15 Nonalcoholic fatty liver disease; LIHC cis rs6066825 0.644 rs2143563 chr20:47320211 A/G cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.59e-12 Colorectal cancer; LIHC cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg13271783 chr10:134563150 INPP5A -0.6 -7.17 -0.36 4.71e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2522056 1.000 rs10900807 chr5:131757480 G/C cg24060327 chr5:131705240 SLC22A5 0.6 7.9 0.39 3.93e-14 Lymphocyte counts;Fibrinogen; LIHC cis rs66569888 0.633 rs11124085 chr2:106758629 A/G cg16099169 chr2:106886729 NA -0.63 -6.76 -0.34 6.1e-11 Facial morphology (factor 23); LIHC cis rs3741404 0.584 rs645461 chr11:63893694 C/T cg18225595 chr11:63971243 STIP1 -0.62 -10.1 -0.48 3.74e-21 Platelet count; LIHC cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg05552183 chr6:42928497 GNMT 0.8 11.63 0.53 1.47e-26 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg10295955 chr4:187884368 NA -0.94 -21.27 -0.75 1.48e-64 Lobe attachment (rater-scored or self-reported); LIHC cis rs1018836 0.770 rs13266461 chr8:91652817 T/C cg16814680 chr8:91681699 NA -0.83 -13.26 -0.58 1.11e-32 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2404602 0.647 rs907593 chr15:77196953 G/A cg03037974 chr15:76606532 NA -0.56 -9.16 -0.44 4.87e-18 Blood metabolite levels; LIHC cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs6499255 1.000 rs11075734 chr16:69801397 G/T cg15192750 chr16:69999425 NA 0.41 6.27 0.32 1.07e-9 IgE levels; LIHC cis rs116095464 0.558 rs10067021 chr5:221490 C/T cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC trans rs1814175 0.645 rs28627251 chr11:50048125 G/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs9916302 0.851 rs9909064 chr17:37500434 G/T cg07936489 chr17:37558343 FBXL20 0.83 13.53 0.59 1.02e-33 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.908 rs7696649 chr4:120322177 G/A cg09307838 chr4:120376055 NA 0.76 11.64 0.53 1.3e-26 Corneal astigmatism; LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg04013166 chr16:89971882 TCF25 -0.56 -7.41 -0.37 9.73e-13 Skin colour saturation; LIHC cis rs9328573 1.000 rs12903084 chr15:100510081 A/G cg09918751 chr15:100517450 ADAMTS17 -0.46 -6.79 -0.34 4.91e-11 Urate levels in lean individuals; LIHC cis rs921968 0.678 rs660432 chr2:219432127 C/T cg18887096 chr2:219472410 PLCD4 0.36 6.33 0.32 7.86e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs12477438 0.798 rs9808541 chr2:99642179 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -10.77 -0.5 1.69e-23 Chronic sinus infection; LIHC cis rs2279817 0.863 rs12023877 chr1:18025633 A/C cg21791023 chr1:18019539 ARHGEF10L 0.41 6.31 0.32 8.89e-10 Neuroticism; LIHC cis rs7224737 1.000 rs2240010 chr17:40278081 T/A cg00647820 chr17:40259828 DHX58 -0.28 -5.83 -0.3 1.26e-8 Fibrinogen levels; LIHC cis rs8077889 0.956 rs4793025 chr17:41841621 T/C cg26893861 chr17:41843967 DUSP3 1.03 11.41 0.53 9.08e-26 Triglycerides; LIHC cis rs2302190 0.882 rs7216856 chr17:56472295 C/T cg05425664 chr17:57184151 TRIM37 -0.48 -5.94 -0.31 7.16e-9 Vitamin D levels; LIHC cis rs7027203 0.797 rs3996254 chr9:96591239 A/G cg14396892 chr9:96623032 NA -0.33 -6.3 -0.32 9.35e-10 DNA methylation (variation); LIHC cis rs3892630 0.588 rs8106748 chr19:33282797 G/A cg22980127 chr19:33182716 NUDT19 1.05 13.8 0.6 9.26e-35 Red blood cell traits; LIHC cis rs7772486 0.790 rs2814880 chr6:146208937 T/G cg05347473 chr6:146136440 FBXO30 0.36 5.88 0.3 9.98e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3018712 0.532 rs2513281 chr11:68417094 A/G cg16797656 chr11:68205561 LRP5 -0.44 -5.79 -0.3 1.56e-8 Total body bone mineral density; LIHC cis rs12702595 0.509 rs2108784 chr7:7266745 A/G cg04827551 chr7:7268805 C1GALT1 -0.33 -6.15 -0.32 2.13e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.55 -7.94 -0.39 3.03e-14 Lymphocyte counts; LIHC cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg10560079 chr2:191398806 TMEM194B 0.5 7.86 0.39 5.12e-14 Pulse pressure; LIHC cis rs4803468 1.000 rs284654 chr19:41928724 G/A cg14132834 chr19:41945861 ATP5SL -0.45 -6.67 -0.34 1.06e-10 Height; LIHC cis rs2061333 1.000 rs2061333 chr19:44614208 A/G cg18700516 chr19:44507157 ZNF230 0.36 5.94 0.31 7.06e-9 Alzheimer's disease; LIHC cis rs7619427 0.507 rs9311347 chr3:44011358 A/G cg24966902 chr3:44043705 NA -0.42 -6.53 -0.33 2.37e-10 Schizophrenia; LIHC cis rs7223966 0.921 rs7225092 chr17:61864005 G/T cg05941027 chr17:61774174 LIMD2 0.34 7.25 0.36 2.87e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9303401 0.659 rs7210700 chr17:56668186 G/A cg25039879 chr17:56429692 SUPT4H1 0.79 8.97 0.44 1.98e-17 Cognitive test performance; LIHC cis rs8114671 0.562 rs959829 chr20:33346047 T/C cg07148914 chr20:33460835 GGT7 -0.57 -8.47 -0.42 7.53e-16 Height; LIHC cis rs539514 0.690 rs1092601 chr13:76309746 C/T cg04757411 chr13:76259545 LMO7 -0.44 -7.85 -0.39 5.28e-14 Type 1 diabetes; LIHC cis rs782590 0.559 rs12617719 chr2:55915826 G/C cg18811423 chr2:55921094 PNPT1 -0.65 -10.37 -0.49 4.18e-22 Metabolic syndrome; LIHC cis rs72781680 0.898 rs79023848 chr2:24038174 C/A cg08917208 chr2:24149416 ATAD2B 0.96 8.09 0.4 1.02e-14 Lymphocyte counts; LIHC cis rs58235267 0.656 rs12713469 chr2:63059927 C/T cg17519650 chr2:63277830 OTX1 -0.61 -10.39 -0.49 3.72e-22 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs35160687 0.644 rs17738058 chr2:86513203 G/C cg23655155 chr2:86332777 POLR1A;PTCD3 0.37 5.85 0.3 1.18e-8 Night sleep phenotypes; LIHC cis rs743757 1.000 rs743756 chr3:50481717 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 0.51 7.98 0.4 2.21e-14 Diastolic blood pressure; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs7937890 0.505 rs4403769 chr11:14450176 C/T cg02886208 chr11:14281011 SPON1 -0.48 -6.76 -0.34 5.83e-11 Mitochondrial DNA levels; LIHC cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg00656387 chr3:40428638 ENTPD3 0.44 7.38 0.37 1.24e-12 Renal cell carcinoma; LIHC cis rs7666738 0.819 rs13139560 chr4:99081188 C/T cg05340658 chr4:99064831 C4orf37 0.7 10.67 0.5 3.88e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs72781680 0.611 rs72783605 chr2:24287864 A/G cg06627628 chr2:24431161 ITSN2 -0.64 -7.43 -0.37 8.75e-13 Lymphocyte counts; LIHC cis rs9303401 0.661 rs9902820 chr17:56637545 A/C cg12560992 chr17:57184187 TRIM37 0.81 13.13 0.58 3.65e-32 Cognitive test performance; LIHC cis rs17376456 0.825 rs17314825 chr5:93234937 A/G cg25358565 chr5:93447407 FAM172A 1.1 10.14 0.48 2.65e-21 Diabetic retinopathy; LIHC cis rs2797160 0.935 rs6940748 chr6:125994080 C/T cg05901451 chr6:126070800 HEY2 -0.4 -6.7 -0.34 8.65e-11 Endometrial cancer; LIHC trans rs1814175 0.817 rs4881658 chr11:49941123 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs611744 0.806 rs374810 chr8:109096029 G/A cg21045802 chr8:109455806 TTC35 0.52 9.0 0.44 1.55e-17 Dupuytren's disease; LIHC cis rs7772486 0.658 rs6570706 chr6:145962922 T/C cg23711669 chr6:146136114 FBXO30 0.63 11.52 0.53 3.73e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.49 -0.33 2.94e-10 Total body bone mineral density; LIHC cis rs7197653 0.667 rs7190070 chr16:68353983 C/T cg03983715 chr16:68378420 PRMT7 -0.53 -6.16 -0.32 1.99e-9 Magnesium levels; LIHC cis rs6964587 0.967 rs2299235 chr7:91627500 C/T cg17063962 chr7:91808500 NA 1.01 19.45 0.72 2.8e-57 Breast cancer; LIHC cis rs7584330 0.518 rs79618460 chr2:238419959 T/C cg08992911 chr2:238395768 MLPH 0.59 6.17 0.32 1.96e-9 Prostate cancer; LIHC cis rs5769765 0.862 rs138897 chr22:50231067 T/C cg26441486 chr22:50317300 CRELD2 0.34 5.91 0.3 8.35e-9 Schizophrenia; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg00106254 chr7:1943704 MAD1L1 -0.48 -8.01 -0.4 1.84e-14 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.764 rs6794193 chr3:47114904 T/C cg16586182 chr3:47516702 SCAP -0.5 -9.13 -0.44 6.17e-18 Colorectal cancer; LIHC cis rs2574704 0.886 rs3856797 chr3:11630613 C/A cg15876825 chr3:11651881 VGLL4 -0.48 -7.77 -0.39 9.17e-14 Body mass index; LIHC cis rs7617773 0.817 rs11928691 chr3:48286765 C/T cg11946769 chr3:48343235 NME6 0.85 10.94 0.51 4.39e-24 Coronary artery disease; LIHC cis rs3784262 0.869 rs4646628 chr15:58255282 T/C cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.49 -0.33 2.97e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs921968 0.643 rs832802 chr2:219386899 C/T cg18887096 chr2:219472410 PLCD4 0.36 6.46 0.33 3.52e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs800082 1.000 rs6440259 chr3:144286614 C/T cg24215973 chr2:240111563 HDAC4 0.42 6.25 0.32 1.2e-9 Smoking behavior; LIHC cis rs9388451 0.839 rs4897157 chr6:126102981 A/T cg06289844 chr6:126071538 HEY2 0.33 5.74 0.3 2.13e-8 Brugada syndrome; LIHC cis rs72627123 0.867 rs79250763 chr14:74491121 G/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.35 0.45 1.18e-18 Morning vs. evening chronotype; LIHC cis rs3812111 0.615 rs9488860 chr6:116495717 G/T cg08036074 chr6:116424633 NT5DC1 -0.53 -8.8 -0.43 6.79e-17 Age-related macular degeneration; LIHC cis rs7772486 0.720 rs6570713 chr6:146075085 G/A cg13319975 chr6:146136371 FBXO30 0.4 6.54 0.33 2.26e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7666738 0.962 rs2865986 chr4:99067907 A/G cg05340658 chr4:99064831 C4orf37 0.69 11.66 0.53 1.08e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs11758351 1.000 rs77961951 chr6:26186075 A/G cg03785755 chr6:26196794 NA 0.53 5.76 0.3 1.89e-8 Gout;Renal underexcretion gout; LIHC cis rs2427308 0.643 rs477859 chr20:60937597 A/G cg09594475 chr20:60884601 LAMA5 -0.53 -6.28 -0.32 1.03e-9 Colorectal cancer; LIHC cis rs9303401 0.614 rs34900851 chr17:56566399 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.39 0.52 1.05e-25 Cognitive test performance; LIHC cis rs2303745 0.544 rs12710308 chr19:17395879 T/A cg02221750 chr19:17393354 ANKLE1 -0.41 -5.89 -0.3 9.37e-9 Systemic lupus erythematosus; LIHC cis rs11758351 1.000 rs3757135 chr6:26200707 G/A cg03854865 chr6:26224070 HIST1H3E 0.63 6.97 0.35 1.59e-11 Gout;Renal underexcretion gout; LIHC cis rs9611565 0.512 rs132784 chr22:42052363 G/A cg03806693 chr22:41940476 POLR3H 0.95 9.89 0.47 1.96e-20 Vitiligo; LIHC cis rs9611565 0.512 rs45500192 chr22:42177899 A/G cg03806693 chr22:41940476 POLR3H -0.98 -10.49 -0.49 1.69e-22 Vitiligo; LIHC cis rs1005277 0.579 rs1740732 chr10:38491385 C/T cg25427524 chr10:38739819 LOC399744 -0.76 -15.37 -0.64 6.6e-41 Extrinsic epigenetic age acceleration; LIHC cis rs7264396 0.790 rs4519606 chr20:34324648 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.71 -0.54 7.04e-27 Total cholesterol levels; LIHC cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg15691649 chr6:25882328 NA -0.53 -7.62 -0.38 2.55e-13 Blood metabolite levels; LIHC cis rs9467773 0.649 rs2145318 chr6:26496603 T/A cg11502198 chr6:26597334 ABT1 0.41 5.87 0.3 1.05e-8 Intelligence (multi-trait analysis); LIHC cis rs5769707 0.632 rs5770601 chr22:50021903 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.45 -0.42 8.41e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg24209194 chr3:40518798 ZNF619 0.46 6.61 0.34 1.5e-10 Renal cell carcinoma; LIHC cis rs9328573 1.000 rs8037666 chr15:100512079 C/T cg09918751 chr15:100517450 ADAMTS17 0.5 7.93 0.39 3.07e-14 Urate levels in lean individuals; LIHC cis rs2749592 0.918 rs1208653 chr10:38253826 C/G cg00409905 chr10:38381863 ZNF37A 0.44 6.96 0.35 1.72e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs11212260 0.573 rs12808887 chr11:107161907 C/T cg25435332 chr11:107328525 CWF19L2 0.64 6.06 0.31 3.66e-9 IgG glycosylation; LIHC cis rs6500602 0.702 rs2270366 chr16:4558615 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.38 -5.78 -0.3 1.67e-8 Schizophrenia; LIHC cis rs734999 0.933 rs4648648 chr1:2512452 G/A cg18854424 chr1:2615690 NA 0.34 7.25 0.36 2.84e-12 Ulcerative colitis; LIHC cis rs17376456 1.000 rs66978370 chr5:93553633 G/A cg25358565 chr5:93447407 FAM172A 1.08 9.8 0.47 3.72e-20 Diabetic retinopathy; LIHC cis rs868036 0.718 rs922494 chr15:68120644 T/C cg24579218 chr15:68104479 NA -0.34 -5.73 -0.3 2.18e-8 Restless legs syndrome; LIHC cis rs17685 0.712 rs60232511 chr7:75800082 A/G cg04592579 chr7:75616294 TMEM120A 0.41 7.0 0.35 1.34e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1401999 1.000 rs4148579 chr3:183685249 T/C cg01324343 chr3:183735012 ABCC5 0.78 12.75 0.57 9.63e-31 Anterior chamber depth; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs7927771 1.000 rs7120333 chr11:47817441 C/T cg20307385 chr11:47447363 PSMC3 -0.44 -5.82 -0.3 1.36e-8 Subjective well-being; LIHC cis rs4319547 0.915 rs10773208 chr12:122970156 T/C cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.2 -0.41 4.94e-15 Body mass index; LIHC trans rs2727020 0.729 rs1164666 chr11:49295867 C/T cg03929089 chr4:120376271 NA -0.8 -14.14 -0.61 4.59e-36 Coronary artery disease; LIHC cis rs6138458 0.620 rs2151462 chr20:24911823 T/C cg26195577 chr20:24973756 C20orf3 1.13 14.83 0.63 9.14e-39 Blood protein levels; LIHC cis rs2777491 1.000 rs316610 chr15:41752852 C/T cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.24 -0.45 2.77e-18 Ulcerative colitis; LIHC cis rs11122272 0.735 rs2739510 chr1:231526718 T/C cg06096015 chr1:231504339 EGLN1 0.47 8.57 0.42 3.57e-16 Hemoglobin concentration; LIHC trans rs59551326 0.920 rs2829722 chr21:26760879 T/C cg09399716 chr2:46890238 NA -0.58 -6.31 -0.32 8.54e-10 Alcohol dependence; LIHC cis rs11955398 0.716 rs10939860 chr5:59999360 C/T cg02684056 chr5:59996105 DEPDC1B 0.4 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs7647973 1.000 rs74471041 chr3:49542543 T/G cg07636037 chr3:49044803 WDR6 -0.54 -6.66 -0.34 1.09e-10 Menarche (age at onset); LIHC trans rs7874142 0.616 rs3811158 chr9:137690877 A/G cg18109838 chr5:88185987 MEF2C -0.36 -7.12 -0.36 6.48e-12 Longevity; LIHC cis rs8180040 0.726 rs4234465 chr3:47026885 C/G cg02527881 chr3:46936655 PTH1R -0.33 -6.47 -0.33 3.38e-10 Colorectal cancer; LIHC cis rs2841277 0.645 rs28380382 chr14:105410827 C/T cg15352829 chr14:105391018 PLD4 -0.43 -9.24 -0.45 2.7e-18 Rheumatoid arthritis; LIHC cis rs8192917 0.832 rs10873219 chr14:25101706 A/C cg03875678 chr14:25103546 GZMB -0.39 -6.48 -0.33 3.24e-10 Vitiligo; LIHC cis rs5753037 0.585 rs7954 chr22:30184950 A/G cg01021169 chr22:30184971 ASCC2 -0.44 -8.79 -0.43 7.39e-17 Type 1 diabetes; LIHC cis rs832540 0.695 rs702686 chr5:56201350 A/G cg24531977 chr5:56204891 C5orf35 -0.48 -7.08 -0.36 8.46e-12 Coronary artery disease; LIHC cis rs10789491 1.000 rs1440487 chr1:47167075 C/T cg15501359 chr1:47185051 KIAA0494 -0.75 -10.47 -0.49 1.89e-22 Response to hepatitis C treatment; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25187967 chr11:77024606 NA 0.42 6.08 0.31 3.18e-9 Pancreatic cancer; LIHC cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.6e-18 Bipolar disorder; LIHC cis rs17685 0.672 rs56343450 chr7:75796235 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.33 -0.32 7.51e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7098414 0.511 rs7916349 chr10:82152638 G/A cg01528321 chr10:82214614 TSPAN14 0.43 6.49 0.33 3.08e-10 Post bronchodilator FEV1; LIHC cis rs10779751 1.000 rs718206 chr1:11294474 T/A cg08854313 chr1:11322531 MTOR 0.8 11.26 0.52 3.07e-25 Body mass index; LIHC cis rs12451471 0.559 rs34746710 chr17:78079224 G/A cg06718696 chr17:78121285 EIF4A3 0.92 10.83 0.51 1.06e-23 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs8017423 0.845 rs114583024 chr14:90727628 T/C cg04374321 chr14:90722782 PSMC1 0.78 15.15 0.63 4.85e-40 Mortality in heart failure; LIHC cis rs875971 1.000 rs778726 chr7:65828731 C/T cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg08677398 chr8:58056175 NA 0.41 6.38 0.33 5.63e-10 Developmental language disorder (linguistic errors); LIHC cis rs7107174 1.000 rs901104 chr11:77930499 C/T cg02023728 chr11:77925099 USP35 0.52 9.63 0.46 1.39e-19 Testicular germ cell tumor; LIHC cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs3806843 0.897 rs2531338 chr5:140136957 A/T cg19875535 chr5:140030758 IK -0.36 -5.9 -0.3 8.88e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4819052 0.851 rs2838856 chr21:46680766 T/G cg22633049 chr21:46681294 NA -0.35 -6.3 -0.32 9.3e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs916888 0.773 rs199451 chr17:44801784 G/A cg07870213 chr5:140052090 DND1 1.04 10.68 0.5 3.59e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9291683 0.632 rs11734786 chr4:10041499 A/C cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.63e-13 Bone mineral density; LIHC cis rs76533333 0.564 rs74344057 chr13:113420293 G/A cg08557188 chr13:113420371 ATP11A -0.8 -6.03 -0.31 4.23e-9 Red cell distribution width; LIHC cis rs6570726 0.791 rs6913727 chr6:145899826 A/G cg23711669 chr6:146136114 FBXO30 0.71 12.2 0.55 1.19e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs10870270 1.000 rs10159943 chr10:133744744 T/C cg08754478 chr10:133766260 PPP2R2D -0.55 -8.1 -0.4 9.51e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6429082 0.633 rs1416473 chr1:235563259 C/T cg26050004 chr1:235667680 B3GALNT2 -0.46 -6.93 -0.35 2.16e-11 Adiposity; LIHC cis rs763121 0.853 rs2072798 chr22:39148483 G/A cg06022373 chr22:39101656 GTPBP1 0.67 12.15 0.55 1.74e-28 Menopause (age at onset); LIHC cis rs6062302 0.522 rs2297428 chr20:62221766 C/T cg06363034 chr20:62225388 GMEB2 -0.45 -7.59 -0.38 3.09e-13 Glioblastoma; LIHC cis rs10751667 0.666 rs10902242 chr11:949700 G/A cg10932868 chr11:921992 NA 0.39 7.31 0.37 1.89e-12 Alzheimer's disease (late onset); LIHC cis rs6964587 1.000 rs11981461 chr7:91692662 A/G cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC trans rs617791 0.530 rs735942 chr11:65749337 A/G cg17712092 chr4:129076599 LARP1B -0.55 -6.64 -0.34 1.25e-10 Breast cancer; LIHC cis rs2933343 0.621 rs6764682 chr3:128568383 G/A cg24203234 chr3:128598194 ACAD9 -0.43 -5.91 -0.3 8.2e-9 IgG glycosylation; LIHC cis rs12594515 1.000 rs12911309 chr15:45985719 G/C cg06207120 chr15:45996521 NA 0.33 6.43 0.33 4.24e-10 Waist circumference;Weight; LIHC cis rs17685 0.736 rs4732594 chr7:75753273 T/C cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4906332 0.901 rs4900575 chr14:103899169 G/C cg04998671 chr14:104000505 TRMT61A -0.46 -6.32 -0.32 7.99e-10 Coronary artery disease; LIHC cis rs9457247 0.967 rs388406 chr6:167409562 A/G cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC trans rs6866721 0.791 rs7704624 chr5:116217105 A/T cg07571379 chr11:134631427 NA 0.29 6.08 0.31 3.17e-9 Body mass index; LIHC cis rs6137287 0.668 rs6082331 chr20:21108350 A/G cg04219410 chr20:21106687 PLK1S1 0.33 5.78 0.3 1.64e-8 Height; LIHC cis rs2204008 0.623 rs4882302 chr12:38415608 T/A cg26384229 chr12:38710491 ALG10B -0.47 -6.07 -0.31 3.35e-9 Bladder cancer; LIHC cis rs6754311 0.628 rs309811 chr2:136625602 A/G cg25344623 chr2:136566232 LCT 0.4 8.18 0.4 5.76e-15 Mosquito bite size; LIHC cis rs3768617 0.510 rs2296293 chr1:183095477 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg18357526 chr6:26021779 HIST1H4A -0.59 -7.06 -0.36 9.25e-12 Blood metabolite levels; LIHC cis rs2228479 0.850 rs11649510 chr16:89851004 A/G cg19635926 chr16:89946313 TCF25 0.51 6.41 0.33 4.89e-10 Skin colour saturation; LIHC cis rs13118159 0.836 rs2276903 chr4:1343405 A/G cg16405210 chr4:1374714 KIAA1530 -0.51 -7.51 -0.38 5.06e-13 Longevity; LIHC cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.33 0.41 1.99e-15 Platelet count; LIHC cis rs1552244 0.572 rs6785976 chr3:10168647 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.74 7.36 0.37 1.4e-12 Alzheimer's disease; LIHC cis rs3809566 1.000 rs3809566 chr15:63333724 A/G cg05771511 chr15:63340396 TPM1 0.46 6.87 0.35 3.02e-11 Platelet count; LIHC cis rs6545883 0.894 rs778158 chr2:61555421 A/G cg15711740 chr2:61764176 XPO1 0.42 5.76 0.3 1.84e-8 Tuberculosis; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg21745873 chr7:4794773 FOXK1 0.41 6.12 0.31 2.6e-9 Bilirubin levels; LIHC trans rs911555 0.755 rs8014013 chr14:103937372 A/G cg17675199 chr6:35436792 RPL10A -0.44 -8.99 -0.44 1.76e-17 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.866 rs3756156 chr4:120524841 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.46 0.46 5.15e-19 Corneal astigmatism; LIHC cis rs2153535 0.580 rs9393022 chr6:8466588 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC trans rs2727020 0.553 rs4980447 chr11:49591662 T/C cg15704280 chr7:45808275 SEPT13 -0.8 -12.07 -0.55 3.42e-28 Coronary artery disease; LIHC cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg12311346 chr5:56204834 C5orf35 -0.58 -7.6 -0.38 2.92e-13 Initial pursuit acceleration; LIHC cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg13047869 chr3:10149882 C3orf24 0.48 5.96 0.31 6.31e-9 Alzheimer's disease; LIHC cis rs7552404 0.961 rs1061337 chr1:76227022 A/G cg22875332 chr1:76189707 ACADM 0.46 6.5 0.33 2.91e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7659604 1.000 rs35224452 chr4:122664677 C/T cg19748678 chr4:122722346 EXOSC9 0.35 5.88 0.3 9.9e-9 Type 2 diabetes; LIHC cis rs9457247 0.967 rs2769346 chr6:167370999 A/G cg12798992 chr6:167411361 FGFR1OP -0.61 -9.81 -0.47 3.56e-20 Crohn's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10334222 chr21:43430726 ZNF295 -0.5 -6.33 -0.32 7.59e-10 Systolic blood pressure; LIHC cis rs780096 0.587 rs6743819 chr2:27567407 G/T cg22903471 chr2:27725779 GCKR -0.49 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.22 -0.32 1.49e-9 Diastolic blood pressure; LIHC cis rs9911578 0.730 rs55759249 chr17:57027135 A/G cg12560992 chr17:57184187 TRIM37 -0.83 -12.68 -0.57 1.77e-30 Intelligence (multi-trait analysis); LIHC cis rs3008870 0.755 rs1925409 chr1:67365089 C/T cg02640540 chr1:67518911 SLC35D1 -0.42 -6.55 -0.33 2.07e-10 Lymphocyte percentage of white cells; LIHC cis rs17376456 0.877 rs28418572 chr5:93144161 A/C cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg03517284 chr6:25882590 NA -0.52 -6.6 -0.34 1.59e-10 Intelligence (multi-trait analysis); LIHC cis rs17401966 1.000 rs17401924 chr1:10384439 A/G cg15208524 chr1:10270712 KIF1B 0.45 6.64 0.34 1.2e-10 Hepatocellular carcinoma; LIHC cis rs9522267 0.535 rs7323829 chr13:112232308 C/G cg10483660 chr13:112241077 NA -0.22 -5.88 -0.3 9.86e-9 Hepatitis; LIHC cis rs2841277 0.708 rs11851053 chr14:105407208 T/C cg21017887 chr14:105400489 NA 0.66 12.84 0.57 4.6e-31 Rheumatoid arthritis; LIHC cis rs3770081 1.000 rs3770082 chr2:86280922 T/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.45 6.24 0.32 1.28e-9 Facial emotion recognition (sad faces); LIHC cis rs6430585 0.528 rs16832417 chr2:136744678 C/T cg07305463 chr2:136567211 LCT -0.38 -5.81 -0.3 1.42e-8 Corneal structure; LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs9914988 0.943 rs9907178 chr17:27124307 G/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.9 -0.35 2.48e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg06418219 chr1:154948305 SHC1;CKS1B 0.49 7.16 0.36 5.01e-12 Prostate cancer; LIHC cis rs655641 1.000 rs2155051 chr11:85713565 A/C cg09030501 chr11:85779252 PICALM -0.5 -6.09 -0.31 3.01e-9 Platelet count; LIHC cis rs35110281 0.782 rs6518302 chr21:45018478 A/G cg21573476 chr21:45109991 RRP1B -0.57 -10.79 -0.5 1.51e-23 Mean corpuscular volume; LIHC cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg25072359 chr17:41440525 NA 0.38 6.07 0.31 3.38e-9 Menopause (age at onset); LIHC cis rs763121 0.925 rs4821797 chr22:39016182 T/C cg21395723 chr22:39101663 GTPBP1 0.37 6.28 0.32 1.06e-9 Menopause (age at onset); LIHC cis rs11112613 0.653 rs2374533 chr12:106047891 A/G cg03607813 chr12:105948248 NA 0.4 6.27 0.32 1.11e-9 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7927592 0.763 rs596494 chr11:68251054 T/G cg20283391 chr11:68216788 NA -0.37 -5.87 -0.3 1.04e-8 Total body bone mineral density; LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs6840360 0.554 rs6849111 chr4:152708874 T/C cg22705602 chr4:152727874 NA -0.4 -8.53 -0.42 4.7e-16 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.913 rs7123564 chr11:68362164 C/T cg01657329 chr11:68192670 LRP5 -0.47 -6.13 -0.31 2.37e-9 Total body bone mineral density; LIHC cis rs8180040 0.726 rs2305634 chr3:47043538 A/G cg16586182 chr3:47516702 SCAP 0.5 9.19 0.45 3.85e-18 Colorectal cancer; LIHC cis rs72949976 0.864 rs10176806 chr2:214022596 T/G cg08319019 chr2:214017104 IKZF2 -0.6 -6.41 -0.33 4.84e-10 Lung cancer;Squamous cell lung carcinoma; LIHC trans rs66573146 0.831 rs67315413 chr4:6987910 T/C cg07817883 chr1:32538562 TMEM39B 1.08 9.42 0.45 6.98e-19 Granulocyte percentage of myeloid white cells; LIHC cis rs1005277 0.579 rs932538 chr10:38381314 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.39 -5.77 -0.3 1.81e-8 Extrinsic epigenetic age acceleration; LIHC cis rs832187 0.813 rs704370 chr3:63868250 A/G cg16258503 chr3:63850278 ATXN7;THOC7 0.48 6.82 0.35 4.07e-11 Schizophrenia; LIHC cis rs17685 0.753 rs1574107 chr7:75685047 A/C cg04610667 chr7:75704037 NA -0.35 -6.31 -0.32 8.43e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9457247 1.000 rs4710147 chr6:167374239 G/A cg23791538 chr6:167370224 RNASET2 0.69 11.77 0.54 4.42e-27 Crohn's disease; LIHC cis rs1005277 0.579 rs1985707 chr10:38434098 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg16680214 chr1:154839983 KCNN3 -0.35 -5.87 -0.3 1.03e-8 Prostate cancer; LIHC cis rs919433 0.647 rs1979239 chr2:198498316 T/G cg10820045 chr2:198174542 NA 0.48 7.55 0.38 4.04e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs3812049 0.784 rs2617617 chr5:127455008 C/T cg16011800 chr17:1958478 HIC1 -0.53 -7.46 -0.37 7.15e-13 Lymphocyte counts;Red cell distribution width; LIHC cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg25204440 chr1:209979598 IRF6 -0.4 -5.93 -0.31 7.59e-9 Monobrow; LIHC cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg08132940 chr7:1081526 C7orf50 -0.79 -6.72 -0.34 7.83e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs1728785 1.000 rs1728764 chr16:68572292 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.82e-9 Ulcerative colitis; LIHC cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg18279126 chr7:2041391 MAD1L1 0.37 6.01 0.31 4.88e-9 Bipolar disorder and schizophrenia; LIHC cis rs7412746 0.658 rs11589458 chr1:150792616 A/G cg17724175 chr1:150552817 MCL1 0.48 9.58 0.46 1.99e-19 Melanoma; LIHC cis rs4919694 1.000 rs12257941 chr10:104833161 C/T cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs12101261 0.556 rs2300516 chr14:81446908 A/G cg06600135 chr14:81408086 NA 0.42 7.65 0.38 2.03e-13 Graves' disease; LIHC cis rs240764 0.658 rs10872628 chr6:101176349 A/G cg09795085 chr6:101329169 ASCC3 -0.53 -7.33 -0.37 1.65e-12 Neuroticism; LIHC cis rs798554 0.610 rs1182173 chr7:2878016 C/G cg13628971 chr7:2884303 GNA12 0.37 5.73 0.3 2.26e-8 Height; LIHC cis rs597539 0.652 rs516425 chr11:68715675 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.79 10.85 0.51 8.91e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6088590 1.000 rs2236270 chr20:33523155 G/T cg24642439 chr20:33292090 TP53INP2 0.76 10.14 0.48 2.75e-21 Coronary artery disease; LIHC cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg05025164 chr4:1340916 KIAA1530 0.42 6.36 0.33 6.49e-10 Obesity-related traits; LIHC cis rs1419980 0.730 rs11054880 chr12:7772069 A/G cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg13409248 chr3:40428643 ENTPD3 -0.42 -7.08 -0.36 8.36e-12 Renal cell carcinoma; LIHC cis rs60871478 0.947 rs62432239 chr7:794576 C/T cg05535760 chr7:792225 HEATR2 0.79 11.3 0.52 2.31e-25 Cerebrospinal P-tau181p levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08616681 chr16:718778 RHOT2 0.42 6.07 0.31 3.43e-9 Pancreatic cancer; LIHC cis rs7917772 0.636 rs7894154 chr10:104524647 G/A cg22532475 chr10:104410764 TRIM8 0.36 6.34 0.32 7.18e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7917772 0.582 rs12411442 chr10:104349531 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs9300255 0.507 rs1727302 chr12:123632930 G/A cg00376283 chr12:123451042 ABCB9 0.7 11.18 0.52 6.05e-25 Neutrophil percentage of white cells; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs6840360 0.809 rs6847303 chr4:152730221 G/A cg22705602 chr4:152727874 NA 0.33 6.96 0.35 1.75e-11 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.967 rs10840148 chr11:8923528 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.06 0.36 9.23e-12 Hemoglobin concentration; LIHC cis rs9534288 0.797 rs992631 chr13:46591989 A/G cg15192986 chr13:46630673 CPB2 0.54 7.91 0.39 3.63e-14 Blood protein levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg09192333 chr22:38142150 TRIOBP -0.49 -6.1 -0.31 2.88e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs4975709 0.686 rs2307118 chr5:1881916 A/C cg15595755 chr5:1867978 NA 0.33 6.12 0.31 2.58e-9 Cardiovascular disease risk factors; LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC trans rs7618501 0.633 rs2252833 chr3:50004209 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.55 8.9 0.43 3.32e-17 Intelligence (multi-trait analysis); LIHC cis rs6456156 0.875 rs55802221 chr6:167517320 G/A cg23791538 chr6:167370224 RNASET2 0.43 6.93 0.35 2.06e-11 Primary biliary cholangitis; LIHC cis rs1816752 0.905 rs7995909 chr13:25013297 T/C cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC cis rs6867032 1.000 rs4246753 chr5:2014721 G/A cg26168224 chr5:2018326 NA 0.33 8.26 0.41 3.33e-15 Gut microbiome composition (winter); LIHC cis rs9640161 0.659 rs11975886 chr7:150010362 G/A cg17279839 chr7:150038598 RARRES2 0.49 10.02 0.48 6.78e-21 Blood protein levels;Circulating chemerin levels; LIHC trans rs11098499 0.955 rs1511018 chr4:120161580 G/T cg25214090 chr10:38739885 LOC399744 0.51 7.75 0.39 1.08e-13 Corneal astigmatism; LIHC cis rs9896933 0.830 rs12450046 chr17:80790388 G/A cg20578329 chr17:80767326 TBCD -0.66 -6.66 -0.34 1.07e-10 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs1670533 0.685 rs56019586 chr4:1059842 C/G cg27284194 chr4:1044797 NA 0.59 8.8 0.43 6.97e-17 Recombination rate (females); LIHC cis rs903552 0.800 rs28470883 chr15:102000824 G/A cg06707286 chr15:102010195 PCSK6 -0.44 -6.06 -0.31 3.54e-9 Diabetic kidney disease; LIHC cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.16 -0.32 2.1e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs6430585 0.583 rs111837148 chr2:136612036 G/A cg07169764 chr2:136633963 MCM6 1.34 22.76 0.78 1.85e-70 Corneal structure; LIHC cis rs2243480 1.000 rs778704 chr7:65863467 T/C cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC cis rs921968 0.541 rs523937 chr2:219437596 G/C cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.37e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs10911363 0.573 rs2761580 chr1:183516989 A/T cg09173681 chr1:183549694 NCF2 0.54 9.54 0.46 2.7e-19 Systemic lupus erythematosus; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08535411 chr7:151826219 NA -0.46 -6.41 -0.33 4.78e-10 Lung function (FEV1/FVC); LIHC cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg13395646 chr4:1353034 KIAA1530 0.64 9.07 0.44 9.45e-18 Obesity-related traits; LIHC cis rs7208859 0.725 rs9915802 chr17:29173058 T/C cg14067834 chr17:29058358 SUZ12P 0.62 6.38 0.33 5.64e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1712517 0.844 rs1163074 chr10:105021762 C/T cg05636881 chr10:105038444 INA 0.38 5.98 0.31 5.68e-9 Migraine; LIHC cis rs1003719 0.788 rs2835584 chr21:38460338 A/T cg10648535 chr21:38446584 PIGP;TTC3 0.77 12.04 0.55 4.45e-28 Eye color traits; LIHC cis rs7095944 0.582 rs10901823 chr10:126488660 C/T cg08799069 chr10:126477246 METTL10 -0.39 -7.08 -0.36 8.25e-12 Asthma; LIHC cis rs1005277 0.540 rs289638 chr10:37923731 G/A cg25427524 chr10:38739819 LOC399744 -0.63 -11.98 -0.54 7.74e-28 Extrinsic epigenetic age acceleration; LIHC cis rs3892630 0.824 rs12976069 chr19:33280084 G/A cg22980127 chr19:33182716 NUDT19 1.01 11.64 0.53 1.36e-26 Red blood cell traits; LIHC cis rs11122272 0.637 rs2808593 chr1:231524228 G/T cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs9733 0.650 rs3738485 chr1:150552392 C/G cg17724175 chr1:150552817 MCL1 -0.38 -7.65 -0.38 2.01e-13 Tonsillectomy; LIHC cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg17554472 chr22:41940697 POLR3H 0.56 6.01 0.31 4.84e-9 Vitiligo; LIHC cis rs3749237 0.595 rs11720264 chr3:49580347 C/T cg06212747 chr3:49208901 KLHDC8B 0.46 5.91 0.3 8.36e-9 Resting heart rate; LIHC cis rs9303401 0.659 rs34426768 chr17:56683385 C/T cg10487724 chr17:56770010 TEX14;RAD51C 1.02 13.95 0.6 2.42e-35 Cognitive test performance; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07991241 chr10:33269695 NA 0.4 6.79 0.34 4.95e-11 Cognitive function; LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg00800038 chr16:89945340 TCF25 -0.69 -10.65 -0.5 4.77e-23 Skin colour saturation; LIHC cis rs9640161 0.789 rs1464752 chr7:150021284 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.79 -0.43 7.56e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs1005277 0.579 rs2505257 chr10:38372664 A/G cg25427524 chr10:38739819 LOC399744 -0.64 -12.21 -0.55 1.04e-28 Extrinsic epigenetic age acceleration; LIHC cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg07061783 chr6:25882402 NA -0.47 -6.48 -0.33 3.29e-10 Blood metabolite levels; LIHC trans rs75804782 0.641 rs59499060 chr2:239341411 C/T cg01134436 chr17:81009848 B3GNTL1 0.8 6.97 0.35 1.59e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs10771431 0.782 rs10771415 chr12:9358223 C/T cg08997352 chr12:9597637 DDX12 -0.58 -9.0 -0.44 1.59e-17 Breast size; LIHC cis rs894734 0.535 rs2366144 chr12:54324069 G/T cg17410650 chr12:54324560 NA -0.41 -7.98 -0.4 2.3e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs2292096 1.000 rs115714635 chr1:200786230 A/T cg11814564 chr1:200748674 CAMSAP1L1 -0.46 -5.74 -0.3 2.06e-8 Epilepsy; LIHC cis rs4555082 0.834 rs2816631 chr14:105739477 G/A cg06808227 chr14:105710500 BRF1 -0.49 -6.05 -0.31 3.79e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs477692 0.789 rs507900 chr10:131398144 A/G cg19680672 chr10:131412579 MGMT 0.44 6.8 0.34 4.78e-11 Response to temozolomide; LIHC cis rs3784262 0.679 rs11071366 chr15:58334244 A/T cg12031962 chr15:58353849 ALDH1A2 -0.36 -6.82 -0.35 4.04e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs2073300 0.609 rs77908916 chr20:23405626 C/G cg12062639 chr20:23401060 NAPB 1.03 13.28 0.58 9.93e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10256972 0.804 rs10275585 chr7:1017339 T/C cg07308232 chr7:1071921 C7orf50 -0.43 -6.64 -0.34 1.2e-10 Longevity;Endometriosis; LIHC cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg06640241 chr16:89574553 SPG7 0.65 10.55 0.5 1.04e-22 Multiple myeloma (IgH translocation); LIHC cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg23172400 chr8:95962367 TP53INP1 -0.4 -8.85 -0.43 4.74e-17 Type 2 diabetes; LIHC cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg18252515 chr7:66147081 NA -1.23 -15.83 -0.65 9.88e-43 Diabetic kidney disease; LIHC cis rs782590 0.967 rs782586 chr2:55836165 A/C cg03859395 chr2:55845619 SMEK2 0.93 16.45 0.66 3.33e-45 Metabolic syndrome; LIHC cis rs6499255 1.000 rs11644838 chr16:69812705 G/C cg15192750 chr16:69999425 NA 0.45 6.78 0.34 5.35e-11 IgE levels; LIHC cis rs1801251 0.963 rs66549961 chr2:233602293 A/G cg08000102 chr2:233561755 GIGYF2 0.75 11.24 0.52 3.81e-25 Coronary artery disease; LIHC cis rs6089584 0.566 rs12373885 chr20:60556393 A/C cg06108461 chr20:60628389 TAF4 -0.52 -6.81 -0.35 4.29e-11 Body mass index; LIHC cis rs3814244 0.515 rs3015002 chr12:68404633 A/C cg15249341 chr12:68405565 NA 0.34 7.12 0.36 6.21e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs6952808 0.501 rs4721429 chr7:2171704 T/C cg02951883 chr7:2050386 MAD1L1 -0.59 -9.46 -0.46 5.21e-19 Bipolar disorder and schizophrenia; LIHC cis rs72781680 0.898 rs72786277 chr2:24062818 T/G cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs12142240 0.698 rs6703669 chr1:46862555 C/T cg14993813 chr1:46806288 NSUN4 -0.66 -5.97 -0.31 5.89e-9 Menopause (age at onset); LIHC cis rs9457247 0.935 rs1187530 chr6:167376812 C/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.85 -0.47 2.62e-20 Crohn's disease; LIHC trans rs8002861 0.934 rs9533685 chr13:44468331 A/G cg17145862 chr1:211918768 LPGAT1 0.67 13.31 0.58 7.33e-33 Leprosy; LIHC cis rs16854884 0.632 rs4446205 chr3:143682607 A/G cg06585982 chr3:143692056 C3orf58 0.58 7.79 0.39 8.18e-14 Economic and political preferences (feminism/equality); LIHC cis rs2839186 1.000 rs2839181 chr21:47685939 A/G cg05896524 chr21:47604654 C21orf56 0.48 7.22 0.36 3.33e-12 Testicular germ cell tumor; LIHC cis rs11628318 0.803 rs10138267 chr14:103035432 C/T cg12046867 chr14:103022105 NA -0.57 -8.43 -0.41 9.98e-16 Platelet count; LIHC trans rs4322600 0.929 rs12885815 chr14:88286403 T/G cg16008221 chr8:17823628 PCM1 -0.4 -6.1 -0.31 2.87e-9 Breast cancer; LIHC cis rs12477438 0.798 rs10196680 chr2:99628617 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.69 -0.5 3.28e-23 Chronic sinus infection; LIHC cis rs919433 0.783 rs2565165 chr2:198233575 T/G cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.8e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2243480 1.000 rs1796228 chr7:66033084 G/A cg18252515 chr7:66147081 NA -1.33 -18.17 -0.7 3.94e-52 Diabetic kidney disease; LIHC cis rs1816752 0.905 rs4770680 chr13:25015248 T/C cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs4975709 0.589 rs4975744 chr5:1860049 A/G cg15595755 chr5:1867978 NA 0.39 8.02 0.4 1.69e-14 Cardiovascular disease risk factors; LIHC cis rs17106184 1.000 rs3789577 chr1:50954128 A/G cg07174182 chr1:51127561 FAF1 0.66 7.45 0.37 7.92e-13 Type 2 diabetes; LIHC cis rs8103278 1.000 rs8108864 chr19:46301671 G/A cg02376097 chr19:46275166 DMPK -0.44 -6.82 -0.35 4.18e-11 Coronary artery disease; LIHC trans rs7395662 0.500 rs7951327 chr11:48925359 C/T cg03929089 chr4:120376271 NA -0.45 -6.72 -0.34 7.46e-11 HDL cholesterol; LIHC cis rs17685 0.672 rs1639623 chr7:75707951 A/G cg16684958 chr7:75615977 POR 0.52 8.65 0.42 2.08e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2760061 0.819 rs708112 chr1:228192452 G/A cg02753203 chr1:228287806 NA 0.48 7.85 0.39 5.36e-14 Diastolic blood pressure; LIHC cis rs1256061 0.603 rs10148269 chr14:64736924 A/G cg23250157 chr14:64679961 SYNE2 0.4 6.03 0.31 4.25e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9911578 1.000 rs1971659 chr17:57004787 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.555 rs11182422 chr12:38522833 A/G cg26384229 chr12:38710491 ALG10B 0.62 8.97 0.44 2.01e-17 Drug-induced liver injury (flucloxacillin); LIHC cis rs1008375 0.966 rs3775924 chr4:17585984 T/C cg16339924 chr4:17578868 LAP3 0.45 6.24 0.32 1.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4516970 0.826 rs59246098 chr6:160149462 C/CA cg25736982 chr6:160182554 ACAT2 0.53 7.96 0.4 2.5e-14 Iron status biomarkers; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.05 -0.31 3.78e-9 Total body bone mineral density; LIHC cis rs1707322 0.716 rs28375469 chr1:46195375 T/C cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.03 -0.31 4.34e-9 Total body bone mineral density; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg26338869 chr17:61819248 STRADA 0.53 7.17 0.36 4.67e-12 Height; LIHC trans rs9951602 0.512 rs7232551 chr18:76650702 G/A cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC trans rs60843830 1.000 rs62114544 chr2:269679 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.54 0.46 2.84e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs3020736 0.500 rs8143153 chr22:42515637 G/C cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.23 -0.32 1.4e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7618501 0.521 rs55692411 chr3:49911155 G/A cg21467203 chr3:49911342 NA -0.61 -11.02 -0.51 2.35e-24 Intelligence (multi-trait analysis); LIHC cis rs1949733 0.582 rs61258495 chr4:8534017 G/A cg11789530 chr4:8429930 ACOX3 -0.57 -7.98 -0.4 2.23e-14 Response to antineoplastic agents; LIHC cis rs2239547 0.607 rs9836178 chr3:52925403 T/C cg18404041 chr3:52824283 ITIH1 0.42 5.78 0.3 1.65e-8 Schizophrenia; LIHC trans rs1814175 0.781 rs1851872 chr11:50009770 A/G cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs2758596 0.826 rs2758606 chr1:156201920 G/A cg25208724 chr1:156163844 SLC25A44 0.75 7.83 0.39 6.12e-14 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs3823572 0.586 rs2971969 chr7:133656264 G/T cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs1008375 0.932 rs11935124 chr4:17668200 G/A cg16339924 chr4:17578868 LAP3 -0.46 -6.08 -0.31 3.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7937682 0.924 rs11213968 chr11:111527629 G/C cg09085632 chr11:111637200 PPP2R1B -1.04 -12.97 -0.57 1.45e-31 Primary sclerosing cholangitis; LIHC trans rs1814175 0.935 rs11040463 chr11:49685574 C/T cg03929089 chr4:120376271 NA -0.89 -17.34 -0.68 8.85e-49 Height; LIHC cis rs2370759 1.000 rs78959390 chr10:32616346 C/T cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs17021463 0.902 rs11097413 chr4:95249286 C/T cg11021082 chr4:95130006 SMARCAD1 0.45 8.25 0.41 3.56e-15 Testicular germ cell tumor; LIHC cis rs11098699 0.800 rs302543 chr4:124205662 G/C cg09941581 chr4:124220074 SPATA5 0.31 5.73 0.3 2.26e-8 Mosquito bite size; LIHC cis rs2235649 0.592 rs2429186 chr16:1969939 C/T cg00564555 chr16:1970112 NA -0.28 -5.84 -0.3 1.2e-8 Blood metabolite levels; LIHC trans rs2243480 1.000 rs4718334 chr7:65789454 G/A cg10756647 chr7:56101905 PSPH -1.01 -12.51 -0.56 7.98e-30 Diabetic kidney disease; LIHC cis rs6964587 1.000 rs12531366 chr7:91683849 C/G cg17063962 chr7:91808500 NA 1.01 19.71 0.73 2.59e-58 Breast cancer; LIHC cis rs2336384 1.000 rs4846085 chr1:12050634 T/C cg13216073 chr1:12042593 MFN2 0.38 5.73 0.3 2.2e-8 Platelet count; LIHC cis rs7546668 0.744 rs1800615 chr1:15832281 C/T cg11706911 chr1:15910989 AGMAT 0.44 6.89 0.35 2.76e-11 Glomerular filtration rate (creatinine); LIHC cis rs56775891 0.959 rs7238071 chr18:77579812 C/T cg13263691 chr18:77568018 NA -0.23 -6.03 -0.31 4.23e-9 Schizophrenia; LIHC cis rs7116495 0.609 rs7121080 chr11:71703935 G/A cg26138937 chr11:71823887 C11orf51 -1.28 -10.45 -0.49 2.31e-22 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27654529 chr19:35418345 ZNF30 0.45 6.93 0.35 2.16e-11 Pancreatic cancer; LIHC cis rs11125080 0.588 rs896211 chr2:46746682 A/G cg02822958 chr2:46747628 ATP6V1E2 -0.64 -6.29 -0.32 9.45e-10 Anti-saccade response;Anti-saccade error rate in psychotic disorders; LIHC cis rs727505 0.909 rs7810427 chr7:124645103 C/T cg23710748 chr7:124431027 NA -0.33 -5.93 -0.31 7.5e-9 Lewy body disease; LIHC cis rs5753618 0.561 rs9606830 chr22:31717799 T/G cg07713946 chr22:31675144 LIMK2 0.43 7.71 0.38 1.36e-13 Colorectal cancer; LIHC trans rs2243480 1.000 rs1964692 chr7:65454183 G/A cg10756647 chr7:56101905 PSPH 1.11 13.6 0.59 5.63e-34 Diabetic kidney disease; LIHC cis rs4595586 0.546 rs11609849 chr12:39258090 C/G cg26384229 chr12:38710491 ALG10B 0.53 7.08 0.36 8.07e-12 Morning vs. evening chronotype; LIHC cis rs3768617 0.510 rs10797839 chr1:183077797 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.45 0.49 2.25e-22 Fuchs's corneal dystrophy; LIHC cis rs3812111 0.774 rs534932 chr6:116425605 C/T cg08036074 chr6:116424633 NT5DC1 -0.64 -11.3 -0.52 2.31e-25 Age-related macular degeneration; LIHC cis rs6500602 0.634 rs2270365 chr16:4526758 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.66 0.38 1.9e-13 Schizophrenia; LIHC cis rs10791323 0.660 rs10791330 chr11:133727535 C/T cg15485101 chr11:133734466 NA 0.25 5.81 0.3 1.39e-8 Childhood ear infection; LIHC cis rs9457247 0.544 rs6920858 chr6:167464630 G/A cg07741184 chr6:167504864 NA 0.36 8.32 0.41 2.16e-15 Crohn's disease; LIHC trans rs1814175 0.645 rs11040671 chr11:49958776 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs6547741 0.743 rs7564625 chr2:27862397 C/T cg27432699 chr2:27873401 GPN1 -0.91 -16.09 -0.66 8.97e-44 Oral cavity cancer; LIHC cis rs7572733 0.534 rs7604700 chr2:198718630 A/G cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg18357526 chr6:26021779 HIST1H4A 0.41 6.2 0.32 1.62e-9 Height; LIHC cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg20887711 chr4:1340912 KIAA1530 -0.7 -10.63 -0.5 5.29e-23 Obesity-related traits; LIHC cis rs4589502 0.920 rs77518050 chr15:67138089 T/C cg09911534 chr15:67153556 NA -0.49 -6.0 -0.31 4.92e-9 Lung cancer (smoking interaction); LIHC cis rs4722166 0.541 rs1800795 chr7:22766645 C/G cg05472934 chr7:22766657 IL6 0.52 8.47 0.42 7.48e-16 Lung cancer; LIHC cis rs7617480 0.648 rs9284885 chr3:48883100 A/C cg07636037 chr3:49044803 WDR6 0.77 9.87 0.47 2.18e-20 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC trans rs877282 0.898 rs10904547 chr10:766283 C/T cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs2576037 0.526 rs4890703 chr18:44522037 A/G cg24750912 chr18:44543259 TCEB3CL;KATNAL2 0.34 6.04 0.31 4.05e-9 Personality dimensions; LIHC cis rs2797160 0.904 rs1612274 chr6:126014907 C/A cg05901451 chr6:126070800 HEY2 0.47 7.88 0.39 4.4e-14 Endometrial cancer; LIHC cis rs6061231 0.916 rs58488796 chr20:60949050 G/C cg03945807 chr20:60948434 NA 0.44 6.87 0.35 3.08e-11 Colorectal cancer; LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg00091569 chr3:40428383 ENTPD3 0.39 6.57 0.33 1.85e-10 Renal cell carcinoma; LIHC cis rs3762637 0.941 rs9837149 chr3:122230845 G/C cg24169773 chr3:122142474 KPNA1 -0.45 -8.96 -0.44 2.12e-17 LDL cholesterol levels; LIHC cis rs1639906 0.895 rs34255795 chr7:2207416 A/G cg04267008 chr7:1944627 MAD1L1 0.43 5.74 0.3 2.08e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs9814567 0.964 rs3856729 chr3:134200925 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.3 -0.55 4.7e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7598759 0.548 rs11693738 chr2:232360484 C/T cg19187155 chr2:232395269 NMUR1 0.58 8.89 0.43 3.51e-17 Noise-induced hearing loss; LIHC cis rs7474896 0.616 rs2474561 chr10:38373544 C/T cg25427524 chr10:38739819 LOC399744 -0.61 -9.32 -0.45 1.43e-18 Obesity (extreme); LIHC cis rs2845885 0.793 rs56241103 chr11:63882364 C/T cg24431193 chr11:63883947 FLRT1;MACROD1 0.72 10.74 0.5 2.22e-23 Body mass index; LIHC cis rs3741404 0.609 rs687581 chr11:63871533 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.69 -11.11 -0.51 1.12e-24 Platelet count; LIHC cis rs11098499 0.865 rs28845498 chr4:120405186 G/A cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.65e-29 Corneal astigmatism; LIHC trans rs61931739 0.500 rs11053198 chr12:34444013 G/C cg26384229 chr12:38710491 ALG10B 0.64 8.06 0.4 1.31e-14 Morning vs. evening chronotype; LIHC cis rs6545883 0.525 rs2049747 chr2:61364154 G/A cg15711740 chr2:61764176 XPO1 0.42 5.89 0.3 9.23e-9 Tuberculosis; LIHC trans rs2209875 0.921 rs752827 chr9:91799117 T/C cg26057616 chr1:222234397 NA 0.38 6.36 0.33 6.46e-10 Pelvic organ prolapse (moderate/severe); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24963443 chr5:180673122 NA 0.42 6.34 0.32 7.17e-10 Lung function (FEV1/FVC); LIHC cis rs2075165 0.901 rs7522860 chr1:156275281 C/T cg08469215 chr1:156261351 TMEM79 0.35 6.22 0.32 1.46e-9 Tonsillectomy; LIHC trans rs2739330 0.828 rs4822451 chr22:24248166 T/G cg06437703 chr8:37914619 EIF4EBP1 -0.47 -7.03 -0.36 1.13e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs909002 0.800 rs2176807 chr1:32092735 T/G cg13919466 chr1:32135498 COL16A1 -0.34 -6.5 -0.33 2.83e-10 Intelligence (multi-trait analysis); LIHC cis rs2625529 0.824 rs7172309 chr15:72384483 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.87 -0.3 1.05e-8 Red blood cell count; LIHC trans rs8073060 0.855 rs12150450 chr17:33868896 A/T cg19694781 chr19:47549865 TMEM160 0.63 6.65 0.34 1.19e-10 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg12463550 chr7:65579703 CRCP -0.66 -6.85 -0.35 3.41e-11 Diabetic kidney disease; LIHC cis rs2439831 1.000 rs101094 chr15:43787322 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.68 0.59 2.85e-34 Lung cancer in ever smokers; LIHC cis rs12291225 0.585 rs12270374 chr11:14375079 T/C cg05501817 chr11:14380813 RRAS2 -0.44 -6.2 -0.32 1.67e-9 Sense of smell; LIHC cis rs7095944 0.614 rs7898003 chr10:126451385 G/A cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.5e-10 Asthma; LIHC cis rs6502050 0.835 rs3935129 chr17:80113381 G/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.97 -0.31 5.98e-9 Life satisfaction; LIHC cis rs244293 0.929 rs244371 chr17:53185225 A/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs250677 0.687 rs40523 chr5:148444186 A/T cg18129178 chr5:148520854 ABLIM3 0.48 7.52 0.38 4.96e-13 Breast cancer; LIHC cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg18404041 chr3:52824283 ITIH1 0.56 8.93 0.43 2.75e-17 Bipolar disorder; LIHC cis rs4845459 0.967 rs4845446 chr1:152590750 C/T cg20634798 chr1:152595351 LCE3A 0.3 6.02 0.31 4.49e-9 Psoriasis; LIHC trans rs526821 0.595 rs551665 chr11:55343268 G/A cg15704280 chr7:45808275 SEPT13 -0.52 -7.8 -0.39 7.82e-14 Pediatric bone mineral density (spine); LIHC cis rs1577917 0.958 rs12198876 chr6:86525476 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.33 -0.37 1.69e-12 Response to antipsychotic treatment; LIHC cis rs10861342 0.892 rs77479670 chr12:105516631 C/T cg23923672 chr12:105501055 KIAA1033 0.66 7.75 0.39 1.08e-13 IgG glycosylation; LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg24693881 chr1:107596107 NA -0.52 -9.28 -0.45 2.02e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3857067 1.000 rs3857068 chr4:95026494 C/G cg11021082 chr4:95130006 SMARCAD1 0.4 7.22 0.36 3.29e-12 QT interval; LIHC trans rs877282 0.945 rs10904554 chr10:786768 T/C cg22713356 chr15:30763199 NA 1.35 12.61 0.56 3.43e-30 Uric acid levels; LIHC cis rs7523273 0.565 rs1998538 chr1:207886487 C/T cg22525895 chr1:207977042 MIR29B2 -0.52 -7.72 -0.39 1.33e-13 Schizophrenia; LIHC cis rs2228479 0.702 rs12600047 chr16:89831630 G/A cg06558623 chr16:89946397 TCF25 0.84 11.48 0.53 5.17e-26 Skin colour saturation; LIHC cis rs7512552 0.768 rs7517441 chr1:150283643 A/T cg15654264 chr1:150340011 RPRD2 -0.68 -11.67 -0.53 9.93e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2832191 0.679 rs2705659 chr21:30363908 G/C cg24692254 chr21:30365293 RNF160 0.85 15.18 0.63 3.92e-40 Dental caries; LIHC cis rs6088590 1.000 rs2076668 chr20:33437621 G/A cg24642439 chr20:33292090 TP53INP2 0.74 9.77 0.47 4.79e-20 Coronary artery disease; LIHC cis rs6442522 0.737 rs905640 chr3:15495840 A/G cg16303742 chr3:15540471 COLQ 0.37 6.21 0.32 1.51e-9 Uric acid levels; LIHC cis rs986417 0.748 rs4381505 chr14:61035968 C/T cg27398547 chr14:60952738 C14orf39 0.71 8.29 0.41 2.64e-15 Gut microbiota (bacterial taxa); LIHC cis rs3741404 0.512 rs4980504 chr11:63873083 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.59 -8.23 -0.41 3.92e-15 Platelet count; LIHC trans rs2749592 0.513 rs1208708 chr10:38085576 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.31 0.32 8.89e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7937890 0.559 rs2575829 chr11:14485021 C/T cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs9914988 0.943 rs12453504 chr17:27119524 C/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7635838 0.722 rs2594982 chr3:11379958 C/T cg00170343 chr3:11313890 ATG7 0.6 10.03 0.48 6.14e-21 HDL cholesterol; LIHC cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 0.92 10.9 0.51 6.06e-24 Platelet count; LIHC cis rs11577318 0.853 rs7537477 chr1:26618829 C/T cg18121669 chr1:26560928 CCDC21 0.48 7.67 0.38 1.77e-13 Granulocyte percentage of myeloid white cells; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00801568 chr15:66649150 TIPIN 0.43 6.56 0.33 1.99e-10 Calcium levels; LIHC cis rs3736594 0.559 rs62141292 chr2:27784300 A/C cg27432699 chr2:27873401 GPN1 0.46 6.84 0.35 3.7e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs35110281 0.811 rs2838339 chr21:45075750 A/G cg21573476 chr21:45109991 RRP1B 0.54 10.47 0.49 1.88e-22 Mean corpuscular volume; LIHC cis rs9326248 0.539 rs7120565 chr11:117042949 T/C cg11861562 chr11:117069780 TAGLN 0.37 5.96 0.31 6.22e-9 Blood protein levels; LIHC cis rs6952808 0.931 rs7810038 chr7:1894116 T/C cg04267008 chr7:1944627 MAD1L1 -0.61 -9.32 -0.45 1.5e-18 Bipolar disorder and schizophrenia; LIHC cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg13393036 chr8:95962371 TP53INP1 -0.37 -8.56 -0.42 4.01e-16 Type 2 diabetes; LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.47 -6.76 -0.34 6.03e-11 Lymphocyte counts; LIHC cis rs2153535 0.580 rs9406159 chr6:8464859 C/G cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7296418 0.922 rs12425009 chr12:123502044 C/T cg06742321 chr12:123595122 PITPNM2 0.31 5.85 0.3 1.14e-8 Platelet count; LIHC cis rs36051895 0.559 rs7850228 chr9:5210671 C/G cg02405213 chr9:5042618 JAK2 0.61 10.35 0.49 4.91e-22 Pediatric autoimmune diseases; LIHC cis rs7572733 0.534 rs700680 chr2:198707950 A/T cg00792783 chr2:198669748 PLCL1 -0.47 -7.07 -0.36 8.68e-12 Dermatomyositis; LIHC trans rs1814175 0.615 rs4545557 chr11:50027329 A/C cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs1577917 0.958 rs34622605 chr6:86456519 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.42 -0.37 9.1e-13 Response to antipsychotic treatment; LIHC cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.16 0.44 4.87e-18 Bipolar disorder; LIHC cis rs3806843 0.900 rs2531341 chr5:140130894 C/T cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23348161 chr2:240964931 NDUFA10 0.48 6.13 0.31 2.46e-9 Lung function (FEV1/FVC); LIHC cis rs4388979 0.595 rs11067292 chr12:109487822 G/A cg03220751 chr12:109490328 USP30 0.6 9.38 0.45 9.36e-19 Plateletcrit;Platelet count; LIHC cis rs7909074 0.933 rs879073 chr10:45399882 C/G cg04218760 chr10:45406644 TMEM72 -0.22 -6.79 -0.34 5.12e-11 Mean corpuscular volume; LIHC cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg12386194 chr3:101231763 SENP7 0.38 6.02 0.31 4.6e-9 Colorectal cancer; LIHC cis rs1371867 0.846 rs1660348 chr8:101315248 A/G cg06002616 chr8:101225028 SPAG1 -0.34 -5.81 -0.3 1.43e-8 Atrioventricular conduction; LIHC cis rs4819052 0.851 rs2236446 chr21:46678985 T/C cg11663144 chr21:46675770 NA -0.3 -5.8 -0.3 1.51e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2549003 1.000 rs3846732 chr5:131816087 T/C cg02551604 chr5:131831745 NA -0.43 -6.52 -0.33 2.51e-10 Asthma (sex interaction); LIHC cis rs7937890 0.904 rs67623158 chr11:14295196 T/C cg22961513 chr11:14280813 SPON1 0.48 7.52 0.38 4.81e-13 Mitochondrial DNA levels; LIHC cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg13393036 chr8:95962371 TP53INP1 -0.43 -10.06 -0.48 5.1e-21 Type 2 diabetes; LIHC cis rs2153535 0.580 rs915351 chr6:8442793 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs7772486 0.817 rs12198065 chr6:146385286 G/C cg05347473 chr6:146136440 FBXO30 0.36 5.88 0.3 9.93e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10463316 0.894 rs7719630 chr5:150760961 C/T cg03212797 chr5:150827313 SLC36A1 -0.44 -6.56 -0.33 2.01e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7772486 0.754 rs702318 chr6:146005873 G/T cg13319975 chr6:146136371 FBXO30 0.48 7.56 0.38 3.7e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs4927850 1.000 rs10881563 chr3:195750225 A/G cg12923728 chr3:195709715 SDHAP1 -0.76 -10.96 -0.51 3.61e-24 Pancreatic cancer; LIHC cis rs7582720 1.000 rs72934545 chr2:203975958 G/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2439831 0.681 rs999047 chr15:43688916 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.88 15.73 0.65 2.44e-42 Lung cancer in ever smokers; LIHC cis rs4820294 0.516 rs12627973 chr22:38096697 A/G cg10587741 chr22:38071170 LGALS1 0.68 9.51 0.46 3.59e-19 Fat distribution (HIV); LIHC cis rs736408 0.812 rs2071508 chr3:52826846 A/G cg18404041 chr3:52824283 ITIH1 0.44 7.32 0.37 1.75e-12 Bipolar disorder; LIHC cis rs67311347 1.000 rs951560 chr3:40463471 A/G cg24209194 chr3:40518798 ZNF619 0.47 7.01 0.35 1.3e-11 Renal cell carcinoma; LIHC cis rs9916302 0.861 rs7503514 chr17:37669884 G/C cg00129232 chr17:37814104 STARD3 -0.41 -6.62 -0.34 1.38e-10 Glomerular filtration rate (creatinine); LIHC cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.5 -0.46 3.7e-19 Bipolar disorder; LIHC cis rs9733 0.596 rs11807058 chr1:150640475 G/A cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs2549003 1.000 rs2070723 chr5:131823187 A/G cg02551604 chr5:131831745 NA -0.45 -6.69 -0.34 9.28e-11 Asthma (sex interaction); LIHC cis rs7845219 0.544 rs4735330 chr8:95917770 A/C cg16049864 chr8:95962084 TP53INP1 -0.43 -6.43 -0.33 4.27e-10 Type 2 diabetes; LIHC cis rs2637266 0.714 rs4475870 chr10:78450724 T/A cg18941641 chr10:78392320 NA 0.27 5.93 0.31 7.46e-9 Pulmonary function; LIHC trans rs61931739 0.500 rs6488224 chr12:34537205 T/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs7238033 0.581 rs7229753 chr18:43312460 A/G cg20610511 chr18:43302872 SLC14A1 0.38 6.33 0.32 7.48e-10 Bladder cancer; LIHC cis rs9828933 0.938 rs9809432 chr3:64002953 G/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.83 -10.21 -0.48 1.5e-21 Type 2 diabetes; LIHC cis rs6964587 1.000 rs1063243 chr7:91726927 A/C cg17063962 chr7:91808500 NA 1.01 19.25 0.72 1.82e-56 Breast cancer; LIHC cis rs6840360 0.571 rs1473305 chr4:152511721 T/G cg22705602 chr4:152727874 NA -0.32 -6.22 -0.32 1.43e-9 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.615 rs12586761 chr14:90820897 A/G cg04374321 chr14:90722782 PSMC1 -0.49 -7.2 -0.36 3.85e-12 Mortality in heart failure; LIHC cis rs8017423 0.935 rs7160304 chr14:90752908 G/T cg04374321 chr14:90722782 PSMC1 0.76 14.39 0.61 4.79e-37 Mortality in heart failure; LIHC cis rs896854 0.548 rs574183 chr8:95973816 A/G cg13393036 chr8:95962371 TP53INP1 0.39 7.63 0.38 2.43e-13 Type 2 diabetes; LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg00656387 chr3:40428638 ENTPD3 0.5 8.4 0.41 1.19e-15 Renal cell carcinoma; LIHC cis rs7131987 0.834 rs12228468 chr12:29453610 A/C cg14222432 chr12:29376421 FAR2 -0.36 -7.04 -0.36 1.09e-11 QT interval; LIHC cis rs17685 0.712 rs10235738 chr7:75773460 G/A cg01364799 chr7:75623366 TMEM120A -0.41 -6.12 -0.31 2.5e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs933688 1.000 rs10058025 chr5:90689052 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.6 0.67 8.33e-46 Smoking behavior; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20743544 chr7:32982957 RP9P 0.4 6.08 0.31 3.14e-9 Cognitive function; LIHC cis rs2066819 1.000 rs78495928 chr12:56635080 G/C cg26734620 chr12:56694298 CS 1.23 10.54 0.5 1.14e-22 Psoriasis vulgaris; LIHC cis rs17685 0.753 rs1637045 chr7:75703895 T/C cg16684958 chr7:75615977 POR 0.51 8.56 0.42 3.74e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7927771 0.524 rs10838771 chr11:47831332 A/G cg20307385 chr11:47447363 PSMC3 -0.66 -9.83 -0.47 3.1e-20 Subjective well-being; LIHC cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg17554472 chr22:41940697 POLR3H -0.56 -6.08 -0.31 3.16e-9 Vitiligo; LIHC cis rs2522056 1.000 rs2522050 chr5:131796609 C/T cg24060327 chr5:131705240 SLC22A5 0.54 7.22 0.36 3.29e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs8027181 1.000 rs2162269 chr15:73090262 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.48 7.37 0.37 1.33e-12 Triglyceride levels; LIHC cis rs6089584 0.587 rs13041784 chr20:60561671 T/C cg06108461 chr20:60628389 TAF4 -0.51 -6.79 -0.34 4.87e-11 Body mass index; LIHC cis rs317689 0.718 rs160827 chr12:69770147 G/A cg22834771 chr12:69754056 YEATS4 -0.39 -5.91 -0.3 8.46e-9 Response to diuretic therapy; LIHC cis rs7103648 0.695 rs10838726 chr11:47568344 C/G cg20307385 chr11:47447363 PSMC3 1.01 16.7 0.67 3.3e-46 Diastolic blood pressure;Systolic blood pressure; LIHC trans rs1814175 0.564 rs12416819 chr11:49755567 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.81 0.35 4.37e-11 Height; LIHC cis rs1003719 0.645 rs8131944 chr21:38547215 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs7027203 0.688 rs4075733 chr9:96624645 C/T cg14598338 chr9:96623480 NA -0.35 -6.99 -0.35 1.44e-11 DNA methylation (variation); LIHC cis rs875971 0.545 rs73146609 chr7:65767464 A/G cg11764359 chr7:65958608 NA 0.58 8.12 0.4 8.7e-15 Aortic root size; LIHC cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg22907277 chr7:1156413 C7orf50 0.5 7.65 0.38 2.03e-13 Longevity;Endometriosis; LIHC cis rs4969178 0.932 rs3744219 chr17:76400236 G/A cg20026190 chr17:76395443 PGS1 0.45 7.12 0.36 6.52e-12 HDL cholesterol levels; LIHC cis rs909002 0.849 rs10914456 chr1:32088171 T/C cg13919466 chr1:32135498 COL16A1 -0.32 -6.16 -0.32 1.99e-9 Intelligence (multi-trait analysis); LIHC cis rs55665837 0.540 rs10128681 chr11:14701576 T/C cg16394018 chr11:14927549 NA 0.4 5.72 0.3 2.27e-8 Vitamin D levels; LIHC cis rs2073300 0.609 rs3827085 chr20:23356985 A/T cg16736954 chr20:23401023 NAPB 0.7 8.15 0.4 6.87e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs780096 0.546 rs35073769 chr2:27731376 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.27 -0.32 1.1e-9 Total body bone mineral density; LIHC cis rs9393692 0.840 rs9358915 chr6:26277268 G/A cg05868516 chr6:26286170 HIST1H4H 0.41 6.31 0.32 8.62e-10 Educational attainment; LIHC cis rs7726839 0.561 rs72703058 chr5:584519 G/A cg09021430 chr5:549028 NA -0.4 -8.48 -0.42 6.68e-16 Obesity-related traits; LIHC trans rs877282 0.733 rs11253342 chr10:765072 A/G cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs2439831 1.000 rs2439841 chr15:43734749 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.77 0.6 1.2e-34 Lung cancer in ever smokers; LIHC cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg15691649 chr6:25882328 NA -0.53 -7.76 -0.39 1.01e-13 Blood metabolite levels; LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.36 0.8 1.03e-76 Prudent dietary pattern; LIHC cis rs344364 0.511 rs911392 chr16:1947259 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.54 -7.17 -0.36 4.76e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs317689 0.690 rs595348 chr12:69638610 T/C cg14784868 chr12:69753453 YEATS4 0.51 7.12 0.36 6.25e-12 Response to diuretic therapy; LIHC cis rs1577917 0.883 rs6454505 chr6:86592362 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.37 -6.58 -0.34 1.74e-10 Response to antipsychotic treatment; LIHC trans rs704178 0.967 rs829079 chr12:21999108 A/C cg13713052 chr3:122102218 FAM162A;CCDC58 0.38 6.15 0.32 2.15e-9 Hippocampal sclerosis of aging; LIHC cis rs67460515 0.926 rs11715591 chr3:161043137 C/T cg03342759 chr3:160939853 NMD3 -0.62 -9.19 -0.45 3.79e-18 Parkinson's disease; LIHC cis rs765787 0.530 rs4775844 chr15:45542048 T/C cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC cis rs311392 0.554 rs2666883 chr8:55100897 A/G cg11783602 chr8:55087084 NA -0.31 -6.14 -0.32 2.29e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs2463822 1.000 rs2513747 chr11:62098735 T/C cg06239285 chr11:62104954 ASRGL1 0.92 6.89 0.35 2.76e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg21724239 chr8:58056113 NA 0.46 6.02 0.31 4.47e-9 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13500430 chr11:2965905 NAP1L4 0.41 6.13 0.31 2.36e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs11098499 0.955 rs1551 chr4:120158500 T/G cg09307838 chr4:120376055 NA 0.74 10.9 0.51 6.12e-24 Corneal astigmatism; LIHC cis rs10791097 0.748 rs4937580 chr11:130734270 T/C cg09137382 chr11:130731461 NA 0.38 5.8 0.3 1.49e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2637266 0.714 rs6480835 chr10:78446863 T/C cg18941641 chr10:78392320 NA 0.27 5.93 0.31 7.46e-9 Pulmonary function; LIHC cis rs796364 0.951 rs10931888 chr2:201022952 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.48 -5.71 -0.3 2.4e-8 Schizophrenia; LIHC trans rs6934970 1.000 rs12212976 chr6:113109747 C/T cg19071452 chr2:152146944 NMI -0.57 -6.19 -0.32 1.77e-9 Bipolar disorder (body mass index interaction); LIHC cis rs3096299 0.685 rs4785568 chr16:89553707 A/G cg02187348 chr16:89574699 SPG7 0.65 10.44 0.49 2.51e-22 Multiple myeloma (IgH translocation); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06613666 chr12:46123163 ARID2;LOC400027 0.5 7.08 0.36 8.3e-12 Pancreatic cancer; LIHC cis rs7584330 0.554 rs7587496 chr2:238387632 A/G cg08992911 chr2:238395768 MLPH 0.67 6.98 0.35 1.58e-11 Prostate cancer; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg08989290 chr16:615782 NHLRC4 0.33 6.46 0.33 3.69e-10 Height; LIHC cis rs1451375 0.617 rs7790758 chr7:50561544 G/A cg14593290 chr7:50529359 DDC -0.61 -10.0 -0.48 7.79e-21 Malaria; LIHC cis rs965469 0.947 rs965470 chr20:3381588 C/G cg25506879 chr20:3388711 C20orf194 -0.56 -6.75 -0.34 6.38e-11 IFN-related cytopenia; LIHC cis rs9914988 0.943 rs34693224 chr17:27079555 C/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.82 -0.35 4.24e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs9549367 0.713 rs3024776 chr13:113827075 A/G cg00898013 chr13:113819073 PROZ 0.46 7.64 0.38 2.24e-13 Platelet distribution width; LIHC cis rs7674212 0.539 rs6533056 chr4:104120997 T/C cg16532752 chr4:104119610 CENPE -0.45 -6.98 -0.35 1.55e-11 Type 2 diabetes; LIHC cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg10802521 chr3:52805072 NEK4 -0.42 -6.93 -0.35 2.1e-11 Bipolar disorder; LIHC cis rs34779708 0.966 rs11010095 chr10:35395948 A/G cg03585969 chr10:35415529 CREM 0.8 11.88 0.54 1.7e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1865760 0.566 rs2032443 chr6:26046802 A/G cg17691542 chr6:26056736 HIST1H1C 0.4 5.79 0.3 1.56e-8 Height; LIHC trans rs11039798 0.588 rs6485857 chr11:48556511 C/A cg15704280 chr7:45808275 SEPT13 0.57 6.34 0.32 7.3e-10 Axial length; LIHC cis rs2073300 1.000 rs6137959 chr20:23442640 T/C cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs11722228 0.508 rs3756227 chr4:10087995 C/A cg26043149 chr18:55253948 FECH 0.77 11.75 0.54 5.12e-27 Gout;Urate levels;Serum uric acid levels; LIHC trans rs61931739 0.500 rs6416261 chr12:34540377 T/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs870825 1.000 rs870825 chr4:185588045 A/G cg04058563 chr4:185651563 MLF1IP 0.68 5.89 0.3 9.32e-9 Blood protein levels; LIHC cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg02951883 chr7:2050386 MAD1L1 0.62 9.48 0.46 4.3e-19 Bipolar disorder and schizophrenia; LIHC cis rs7903847 0.620 rs17112674 chr10:99122178 C/T cg06359132 chr10:99160096 RRP12 0.4 6.32 0.32 8.22e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs17685 0.753 rs55812043 chr7:75747241 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.2 -0.32 1.6e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2197308 0.765 rs12230545 chr12:37927114 C/T cg26384229 chr12:38710491 ALG10B -0.48 -6.75 -0.34 6.3e-11 Morning vs. evening chronotype; LIHC cis rs7618501 0.966 rs2246832 chr3:49881134 A/T cg24110177 chr3:50126178 RBM5 -0.45 -6.93 -0.35 2.04e-11 Intelligence (multi-trait analysis); LIHC trans rs660498 0.516 rs620664 chr10:27746471 C/T cg07529754 chr2:50575098 NRXN1 0.4 6.25 0.32 1.21e-9 Asthma (childhood onset); LIHC cis rs2228479 0.850 rs62054640 chr16:89823157 C/T cg04013166 chr16:89971882 TCF25 0.5 6.13 0.31 2.39e-9 Skin colour saturation; LIHC cis rs8067354 0.830 rs2453913 chr17:57860150 G/T cg13753209 chr17:57696993 CLTC 0.56 8.59 0.42 3.15e-16 Hemoglobin concentration; LIHC cis rs546131 1.000 rs546131 chr11:34851760 G/C cg11058730 chr11:34937778 PDHX;APIP 0.6 9.4 0.45 8.36e-19 Lung disease severity in cystic fibrosis; LIHC cis rs11671005 0.693 rs11084542 chr19:58932099 T/A cg25952890 chr19:58913133 NA 0.67 7.2 0.36 3.89e-12 Mean platelet volume; LIHC cis rs904251 0.828 rs2797803 chr6:37487340 T/C cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.38e-12 Cognitive performance; LIHC cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg04772025 chr11:68637568 NA 0.45 6.07 0.31 3.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs67478160 0.619 rs12437066 chr14:104236844 A/C cg08213375 chr14:104286397 PPP1R13B 0.53 10.1 0.48 3.78e-21 Schizophrenia; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.97 -0.31 5.99e-9 Total body bone mineral density; LIHC cis rs6502050 0.835 rs9902485 chr17:80093701 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.59e-9 Life satisfaction; LIHC cis rs57590327 0.679 rs17019030 chr3:81552062 C/T cg07356753 chr3:81810745 GBE1 -0.45 -6.17 -0.32 1.9e-9 Extraversion; LIHC cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg02244288 chr16:89573955 SPG7 -0.3 -5.8 -0.3 1.49e-8 Multiple myeloma (IgH translocation); LIHC cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg16145915 chr7:1198662 ZFAND2A -0.34 -8.37 -0.41 1.53e-15 Longevity;Endometriosis; LIHC cis rs311392 0.525 rs2013503 chr8:55104343 C/T cg20636351 chr8:55087400 NA -0.34 -7.09 -0.36 7.97e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs7116495 1.000 rs520025 chr11:71562832 C/G cg26138937 chr11:71823887 C11orf51 0.7 6.74 0.34 6.73e-11 Severe influenza A (H1N1) infection; LIHC trans rs3808502 0.527 rs2736374 chr8:11113828 A/G cg21298408 chr8:18027853 NAT1 0.28 6.28 0.32 1.04e-9 Neuroticism; LIHC cis rs7945718 0.621 rs11022464 chr11:12685477 T/C cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg22907277 chr7:1156413 C7orf50 0.54 8.15 0.4 6.95e-15 Longevity;Endometriosis; LIHC cis rs4845570 1.000 rs11585294 chr1:151769887 A/C cg07092448 chr1:151763213 TDRKH -0.67 -6.87 -0.35 3.04e-11 Coronary artery disease; LIHC cis rs881375 0.678 rs7021049 chr9:123683982 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 6.44 0.33 3.95e-10 Rheumatoid arthritis; LIHC cis rs9914988 0.943 rs9902953 chr17:27139834 C/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs651907 0.535 rs11717638 chr3:101505468 A/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs7116495 1.000 rs548127 chr11:71575294 C/G cg26138937 chr11:71823887 C11orf51 -0.73 -7.23 -0.36 3.15e-12 Severe influenza A (H1N1) infection; LIHC cis rs6063312 0.667 rs9679994 chr20:47281853 T/C cg18078177 chr20:47281410 PREX1 0.55 8.88 0.43 3.95e-17 Tonometry; LIHC cis rs7089973 0.604 rs12218498 chr10:116578489 T/C cg23260525 chr10:116636907 FAM160B1 0.36 6.84 0.35 3.7e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1144333 0.655 rs12405994 chr1:76435420 A/T cg22875332 chr1:76189707 ACADM 0.41 6.1 0.31 2.89e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs4820294 0.926 rs62236671 chr22:38069305 G/A cg26138144 chr22:38071188 LGALS1 0.76 14.14 0.61 4.78e-36 Fat distribution (HIV); LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs2574704 0.886 rs13078952 chr3:11630963 T/A cg15876825 chr3:11651881 VGLL4 -0.47 -7.68 -0.38 1.66e-13 Body mass index; LIHC cis rs2439831 0.867 rs2614811 chr15:43913487 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.56 6.84 0.35 3.77e-11 Lung cancer in ever smokers; LIHC cis rs798766 0.779 rs55895920 chr4:1735930 C/T cg21231739 chr4:1642635 FAM53A -0.37 -5.94 -0.31 7e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs3749237 0.595 rs11720264 chr3:49580347 C/T cg03060546 chr3:49711283 APEH 0.64 10.46 0.49 2.15e-22 Resting heart rate; LIHC cis rs79149102 0.579 rs28394281 chr15:75326754 C/G cg16226627 chr15:75307476 SCAMP5 0.54 9.74 0.47 5.98e-20 Lung cancer; LIHC cis rs8103278 1.000 rs36091860 chr19:46312880 G/A cg11657440 chr19:46296263 DMWD -0.53 -8.28 -0.41 2.78e-15 Coronary artery disease; LIHC cis rs2153535 0.580 rs7767926 chr6:8453557 A/G cg21535247 chr6:8435926 SLC35B3 0.63 8.45 0.42 8.36e-16 Motion sickness; LIHC cis rs477692 0.792 rs12762024 chr10:131441055 G/C cg19680672 chr10:131412579 MGMT 0.39 5.78 0.3 1.68e-8 Response to temozolomide; LIHC cis rs4819052 0.851 rs3673 chr21:46681775 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.69 11.04 0.51 1.93e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2257205 0.667 rs7342862 chr17:56816561 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.64 -0.34 1.21e-10 Pancreatic cancer; LIHC cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg03517284 chr6:25882590 NA 0.58 7.81 0.39 6.88e-14 Blood metabolite levels; LIHC cis rs881375 1.000 rs6478486 chr9:123655329 T/C cg14580859 chr9:123691850 NA 0.38 6.55 0.33 2.16e-10 Rheumatoid arthritis; LIHC cis rs2731664 0.792 rs2630764 chr5:176880085 C/T cg23176889 chr5:176863531 GRK6 -0.71 -12.43 -0.56 1.56e-29 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg13047869 chr3:10149882 C3orf24 0.5 6.08 0.31 3.23e-9 Alzheimer's disease; LIHC cis rs875971 0.862 rs13226170 chr7:65999298 G/A cg18252515 chr7:66147081 NA -0.46 -6.82 -0.35 4.19e-11 Aortic root size; LIHC cis rs2153535 0.563 rs3117071 chr6:8537908 C/T cg07606381 chr6:8435919 SLC35B3 0.78 11.18 0.52 5.97e-25 Motion sickness; LIHC trans rs4332037 0.851 rs1403175 chr7:1964357 A/T cg11693508 chr17:37793320 STARD3 -0.73 -7.68 -0.38 1.7e-13 Bipolar disorder; LIHC cis rs3008870 0.755 rs2755271 chr1:67474977 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.62 10.44 0.49 2.4e-22 Lymphocyte percentage of white cells; LIHC cis rs7106204 1.000 rs4622259 chr11:24215789 A/G ch.11.24196551F chr11:24239977 NA 0.68 6.83 0.35 3.89e-11 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6089584 1.000 rs6089587 chr20:60564829 C/T cg12751644 chr20:60527061 NA -0.37 -6.09 -0.31 3.12e-9 Body mass index; LIHC cis rs10924970 0.805 rs12030234 chr1:235517557 T/G cg26050004 chr1:235667680 B3GALNT2 0.4 5.79 0.3 1.58e-8 Asthma; LIHC cis rs2576037 0.562 rs9959877 chr18:44522293 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.71 11.12 0.52 1e-24 Personality dimensions; LIHC cis rs250677 0.687 rs250674 chr5:148438597 A/G cg18129178 chr5:148520854 ABLIM3 0.47 7.44 0.37 8.27e-13 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14751398 chr6:20402153 E2F3 0.47 6.68 0.34 9.97e-11 Pancreatic cancer; LIHC cis rs473651 0.967 rs483042 chr2:239335320 A/G cg21699342 chr2:239360505 ASB1 0.36 6.92 0.35 2.24e-11 Multiple system atrophy; LIHC cis rs2404602 0.735 rs2436996 chr15:76817420 C/T cg23625390 chr15:77176239 SCAPER -0.5 -8.24 -0.41 3.6e-15 Blood metabolite levels; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg05064044 chr6:292385 DUSP22 -0.58 -8.01 -0.4 1.8e-14 Menopause (age at onset); LIHC cis rs9733 0.527 rs11204694 chr1:150653391 G/A cg18016565 chr1:150552671 MCL1 0.59 11.49 0.53 4.8e-26 Tonsillectomy; LIHC trans rs7246657 0.882 rs10412043 chr19:37826626 A/C cg24637308 chr11:6592297 DNHD1 0.44 6.18 0.32 1.78e-9 Coronary artery calcification; LIHC cis rs1448094 0.522 rs12313658 chr12:86271063 C/T cg02569458 chr12:86230093 RASSF9 0.43 5.91 0.3 8.43e-9 Major depressive disorder; LIHC cis rs11673344 0.832 rs8104296 chr19:37516536 G/A cg27390819 chr19:37464633 NA -0.51 -6.24 -0.32 1.26e-9 Obesity-related traits; LIHC cis rs17711722 0.727 rs781151 chr7:65479878 T/C cg11764359 chr7:65958608 NA 0.68 8.84 0.43 5.02e-17 Calcium levels; LIHC cis rs4919087 1.000 rs12221430 chr10:99061386 C/G cg25902810 chr10:99078978 FRAT1 0.71 10.94 0.51 4.47e-24 Monocyte count; LIHC cis rs7633857 0.512 rs1374787 chr3:160700144 C/T cg03342759 chr3:160939853 NMD3 -0.41 -5.82 -0.3 1.35e-8 Educational attainment (years of education); LIHC cis rs17685 0.712 rs10235086 chr7:75833138 G/T cg16684958 chr7:75615977 POR 0.49 8.07 0.4 1.17e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9902453 0.904 rs4528633 chr17:28356136 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs140364877 1 rs140364877 chr7:1885178 C/T cg10360139 chr7:1886902 MAD1L1 -0.39 -6.0 -0.31 5.03e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs2075671 0.810 rs12531792 chr7:100280624 G/A cg20848291 chr7:100343083 ZAN -0.47 -6.75 -0.34 6.52e-11 Other erythrocyte phenotypes; LIHC cis rs9303280 0.806 rs34189114 chr17:38032460 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.15 0.36 5.31e-12 Self-reported allergy; LIHC cis rs3008870 0.755 rs2815366 chr1:67499930 C/T cg02640540 chr1:67518911 SLC35D1 0.45 7.0 0.35 1.37e-11 Lymphocyte percentage of white cells; LIHC cis rs12926788 0.640 rs73551577 chr16:24845143 G/A cg04756594 chr16:24857601 SLC5A11 0.58 8.74 0.43 1.06e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs11588062 0.703 rs11589812 chr1:46858748 C/T cg15696662 chr1:46669221 C1orf190;POMGNT1 0.44 6.79 0.34 4.83e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6456156 0.526 rs3093025 chr6:167532731 A/G cg07741184 chr6:167504864 NA -0.28 -6.94 -0.35 1.96e-11 Primary biliary cholangitis; LIHC cis rs2257205 0.667 rs7214805 chr17:56931895 C/G cg05425664 chr17:57184151 TRIM37 -0.61 -6.67 -0.34 1.05e-10 Pancreatic cancer; LIHC cis rs79839061 0.656 rs11726912 chr4:887868 A/C cg07828340 chr4:882639 GAK 0.85 7.43 0.37 8.5e-13 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.663 rs9996501 chr4:120238918 C/A cg09307838 chr4:120376055 NA 0.72 11.19 0.52 5.63e-25 Corneal astigmatism; LIHC cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.882 rs55808392 chr3:10054681 C/T cg08888203 chr3:10149979 C3orf24 0.46 5.96 0.31 6.31e-9 Alzheimer's disease; LIHC cis rs734999 0.545 rs7364820 chr1:2556709 G/A cg18854424 chr1:2615690 NA 0.34 7.4 0.37 1.09e-12 Ulcerative colitis; LIHC cis rs8038465 0.622 rs2509 chr15:73859488 A/T cg15420318 chr15:73925796 NPTN -0.46 -6.95 -0.35 1.81e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs875971 0.545 rs6979636 chr7:65741625 A/G cg26939375 chr7:64535504 NA 0.41 6.44 0.33 4.13e-10 Aortic root size; LIHC cis rs1185460 0.967 rs1784302 chr11:118940957 C/G cg23280166 chr11:118938394 VPS11 0.6 8.1 0.4 9.87e-15 Coronary artery disease; LIHC cis rs11792861 0.781 rs28361106 chr9:111762385 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 8.91 0.43 3.19e-17 Menarche (age at onset); LIHC cis rs12701220 0.894 rs12539012 chr7:1052133 G/A cg00990874 chr7:1149470 C7orf50 -0.69 -9.72 -0.47 7.03e-20 Bronchopulmonary dysplasia; LIHC cis rs2576037 0.796 rs2247221 chr18:44580082 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.16 -0.36 5.06e-12 Personality dimensions; LIHC cis rs35160687 0.623 rs11127021 chr2:86474919 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.39 6.31 0.32 8.7e-10 Night sleep phenotypes; LIHC cis rs6430585 0.527 rs62168833 chr2:136449254 G/A cg07169764 chr2:136633963 MCM6 0.67 8.57 0.42 3.67e-16 Corneal structure; LIHC cis rs96067 0.711 rs272833 chr1:36622870 C/G cg24686825 chr1:36642396 MAP7D1 -0.65 -10.07 -0.48 4.81e-21 Corneal structure; LIHC cis rs919433 1.000 rs6761919 chr2:198163328 A/G cg03934865 chr2:198174659 NA -0.61 -9.95 -0.47 1.16e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1348850 0.598 rs1405717 chr2:178500101 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 8.16 0.4 6.43e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg13393036 chr8:95962371 TP53INP1 -0.39 -8.85 -0.43 4.93e-17 Type 2 diabetes; LIHC cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg05564831 chr3:52568323 NT5DC2 0.35 5.83 0.3 1.27e-8 Bipolar disorder; LIHC cis rs34330 0.562 rs11055023 chr12:12853197 A/G cg04607235 chr12:12878440 APOLD1 -0.74 -9.1 -0.44 7.65e-18 Systemic lupus erythematosus; LIHC cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg13395646 chr4:1353034 KIAA1530 -0.63 -8.81 -0.43 6.21e-17 Obesity-related traits; LIHC cis rs916888 0.773 rs199457 chr17:44795469 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.97 0.35 1.65e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9549367 0.756 rs3861723 chr13:113910926 A/G cg18105134 chr13:113819100 PROZ -0.57 -10.09 -0.48 3.85e-21 Platelet distribution width; LIHC cis rs7772486 0.790 rs2265472 chr6:146220758 G/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.86 -0.3 1.1e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs4906332 0.933 rs34606394 chr14:103915636 G/A cg17675199 chr6:35436792 RPL10A 0.34 6.68 0.34 9.43e-11 Coronary artery disease; LIHC trans rs1005277 0.579 rs1621040 chr10:38497232 T/C cg17830980 chr10:43048298 ZNF37B -0.5 -9.55 -0.46 2.56e-19 Extrinsic epigenetic age acceleration; LIHC cis rs9393692 0.905 rs9393693 chr6:26277408 C/A cg05868516 chr6:26286170 HIST1H4H 0.41 6.31 0.32 8.62e-10 Educational attainment; LIHC cis rs12369635 1.000 rs11060121 chr12:129564206 C/T cg01909103 chr12:129572610 TMEM132D -0.61 -6.12 -0.31 2.51e-9 Schizophrenia (inflammation and infection response interaction); LIHC cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg16049864 chr8:95962084 TP53INP1 -0.57 -9.35 -0.45 1.16e-18 Type 2 diabetes; LIHC cis rs9596863 1.000 rs7328970 chr13:54424225 G/C ch.13.53330881F chr13:54432880 NA -0.43 -6.0 -0.31 5.16e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg18279126 chr7:2041391 MAD1L1 0.38 6.45 0.33 3.84e-10 Bipolar disorder and schizophrenia; LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg10755058 chr3:40428713 ENTPD3 0.41 6.89 0.35 2.77e-11 Renal cell carcinoma; LIHC cis rs7914558 0.646 rs10883796 chr10:104655315 G/A cg15744005 chr10:104629667 AS3MT -0.35 -7.38 -0.37 1.22e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs67981189 0.572 rs7156009 chr14:71515431 G/A cg15816911 chr14:71606274 NA 0.42 6.85 0.35 3.4e-11 Schizophrenia; LIHC cis rs72772090 0.634 rs72773912 chr5:96107801 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.63 -7.08 -0.36 8.02e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs546131 0.642 rs12794294 chr11:34827518 T/C cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.35 -0.32 6.82e-10 Lung disease severity in cystic fibrosis; LIHC trans rs10506458 0.834 rs73125186 chr12:63373400 C/T cg22491629 chr6:157744540 C6orf35 -0.58 -10.04 -0.48 5.67e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs2239547 0.563 rs4687699 chr3:53101224 C/T cg11645453 chr3:52864694 ITIH4 0.28 7.02 0.36 1.17e-11 Schizophrenia; LIHC cis rs9457247 0.515 rs1951459 chr6:167402536 G/A cg12798992 chr6:167411361 FGFR1OP -0.5 -8.05 -0.4 1.36e-14 Crohn's disease; LIHC cis rs79387448 0.745 rs75644281 chr2:103151316 A/T cg09003973 chr2:102972529 NA 0.85 7.47 0.37 6.82e-13 Gut microbiota (bacterial taxa); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25356086 chr21:33764900 C21orf119;URB1 0.45 6.45 0.33 3.76e-10 Pancreatic cancer; LIHC cis rs34779708 0.733 rs7914560 chr10:35548099 G/A cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC trans rs2270927 0.510 rs2358712 chr5:75580687 A/G cg13563193 chr19:33072644 PDCD5 0.97 9.17 0.44 4.59e-18 Mean corpuscular volume; LIHC cis rs17376456 0.825 rs12716454 chr5:93272279 A/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs2303745 0.589 rs6512182 chr19:17399476 G/T cg10664184 chr19:17420304 DDA1 0.46 5.86 0.3 1.07e-8 Systemic lupus erythematosus; LIHC cis rs35110281 0.659 rs11909064 chr21:45092095 G/C cg01579765 chr21:45077557 HSF2BP -0.32 -5.85 -0.3 1.13e-8 Mean corpuscular volume; LIHC cis rs7572733 0.555 rs2342558 chr2:198920142 T/C cg03934865 chr2:198174659 NA 0.43 6.1 0.31 2.89e-9 Dermatomyositis; LIHC cis rs9486715 0.867 rs2499775 chr6:97007340 C/T cg06623918 chr6:96969491 KIAA0776 -0.87 -15.61 -0.65 7.33e-42 Headache; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03843852 chr15:55611099 PIGB -0.44 -6.67 -0.34 1.01e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17426592 chr5:6712363 NA 0.44 6.68 0.34 9.69e-11 Lung function (FEV1/FVC); LIHC cis rs2404602 0.583 rs11072580 chr15:76540231 G/A cg22467129 chr15:76604101 ETFA -0.38 -6.32 -0.32 8.19e-10 Blood metabolite levels; LIHC cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg16606324 chr3:10149918 C3orf24 0.52 5.88 0.3 9.99e-9 Alzheimer's disease; LIHC cis rs35110281 0.548 rs7276316 chr21:45029333 A/T cg01579765 chr21:45077557 HSF2BP -0.35 -6.68 -0.34 9.89e-11 Mean corpuscular volume; LIHC cis rs7945718 0.781 rs11022513 chr11:12840986 C/T cg25843174 chr11:12811716 TEAD1 -0.27 -6.31 -0.32 8.61e-10 Educational attainment (years of education); LIHC cis rs11628318 0.614 rs1190335 chr14:103111358 T/C cg23461800 chr14:103021989 NA -0.39 -5.94 -0.31 7.2e-9 Platelet count; LIHC cis rs16828019 0.852 rs71648536 chr1:41632008 T/A cg03387723 chr1:41708464 SCMH1 -0.42 -6.98 -0.35 1.59e-11 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg12310025 chr6:25882481 NA -0.44 -6.7 -0.34 8.61e-11 Height; LIHC cis rs7582720 0.943 rs114372659 chr2:203715514 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.98 0.31 5.56e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4638749 0.677 rs10203004 chr2:108826535 G/T cg25838818 chr2:108905173 SULT1C2 -0.4 -7.0 -0.35 1.37e-11 Blood pressure; LIHC cis rs17433710 0.516 rs10737487 chr1:162667331 G/A cg01063088 chr1:162760584 HSD17B7 0.44 6.32 0.32 8.32e-10 Dupuytren's disease; LIHC cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg06466757 chr4:1255808 NA 0.34 5.79 0.3 1.61e-8 Obesity-related traits; LIHC cis rs7428 0.527 rs4459734 chr2:85547429 G/T cg24342717 chr2:85555507 TGOLN2 -0.79 -10.2 -0.48 1.67e-21 Ear protrusion; LIHC cis rs796364 0.760 rs56225698 chr2:200910653 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs9902453 0.765 rs2264303 chr17:28055348 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -13.61 -0.59 5.27e-34 Coffee consumption (cups per day); LIHC cis rs9646954 0.542 rs4149512 chr2:101022886 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.41 0.41 1.16e-15 Intelligence (multi-trait analysis); LIHC trans rs4820294 0.669 rs7287340 chr22:38054325 C/T cg19894588 chr14:64061835 NA -0.47 -7.44 -0.37 8.1e-13 Fat distribution (HIV); LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg23131131 chr22:24373011 LOC391322 -0.64 -9.28 -0.45 1.99e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3806843 0.801 rs801170 chr5:140115343 C/T cg19875535 chr5:140030758 IK -0.39 -6.3 -0.32 9.22e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1790761 0.692 rs10896179 chr11:67316928 C/A cg01069141 chr11:67398826 TBX10;NUDT8 0.36 6.49 0.33 2.93e-10 Mean corpuscular volume; LIHC cis rs6430585 0.583 rs4594504 chr2:136625113 A/C cg15123519 chr2:136567270 LCT -0.38 -5.99 -0.31 5.29e-9 Corneal structure; LIHC cis rs9549367 0.789 rs7994324 chr13:113906497 T/C cg18105134 chr13:113819100 PROZ -0.67 -11.57 -0.53 2.42e-26 Platelet distribution width; LIHC cis rs2834256 1.000 rs2834259 chr21:35133091 C/T cg14850771 chr21:34775459 IFNGR2 0.38 5.78 0.3 1.66e-8 Red cell distribution width; LIHC cis rs807029 0.533 rs2863095 chr10:102746503 C/T cg25179470 chr10:102756915 LZTS2 0.45 6.36 0.32 6.65e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4407350 0.870 rs5765716 chr22:44915251 T/C cg11695653 chr22:44894386 LDOC1L -0.36 -6.2 -0.32 1.6e-9 Intelligence (multi-trait analysis); LIHC cis rs11190604 0.945 rs2495735 chr10:102338609 G/A cg07080220 chr10:102295463 HIF1AN 0.53 7.64 0.38 2.19e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1448094 0.512 rs61930137 chr12:86242930 C/T cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs11122272 0.701 rs2011383 chr1:231479788 T/A cg06096015 chr1:231504339 EGLN1 0.5 9.14 0.44 5.69e-18 Hemoglobin concentration; LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg06656553 chr16:89960601 TCF25 -0.48 -5.98 -0.31 5.65e-9 Skin colour saturation; LIHC cis rs5769765 0.862 rs56377703 chr22:50306940 C/T cg09182678 chr22:50328711 NA -0.44 -6.32 -0.32 8.36e-10 Schizophrenia; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.18 -0.4 5.58e-15 Lymphocyte counts; LIHC cis rs10791097 0.694 rs2155752 chr11:130755998 C/T cg22079354 chr11:130786696 SNX19 0.41 5.82 0.3 1.35e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9393692 0.645 rs9467703 chr6:26318903 A/G cg13736514 chr6:26305472 NA -0.4 -6.13 -0.31 2.44e-9 Educational attainment; LIHC cis rs7772486 0.713 rs2328704 chr6:146020494 T/C cg23711669 chr6:146136114 FBXO30 -0.59 -10.92 -0.51 5.31e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs9325144 0.600 rs1817648 chr12:38733424 C/T cg26384229 chr12:38710491 ALG10B -0.58 -8.14 -0.4 7.19e-15 Morning vs. evening chronotype; LIHC cis rs2832077 0.527 rs9981922 chr21:30212718 A/G cg03476357 chr21:30257390 N6AMT1 -0.49 -6.69 -0.34 9.28e-11 Cognitive test performance; LIHC cis rs6009527 0.711 rs8141990 chr22:49570455 T/G cg12746016 chr22:49560550 NA 0.26 6.14 0.32 2.27e-9 Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg23933399 chr1:1462973 ATAD3A 0.41 6.62 0.34 1.43e-10 Immature fraction of reticulocytes; LIHC trans rs10506458 0.915 rs79133015 chr12:63396838 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.75 -10.68 -0.5 3.56e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs10751667 0.643 rs7396951 chr11:927355 G/A ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC trans rs7395662 0.591 rs10838968 chr11:48595046 A/G cg15704280 chr7:45808275 SEPT13 -0.47 -7.03 -0.36 1.14e-11 HDL cholesterol; LIHC cis rs17685 0.753 rs13240404 chr7:75675719 C/T cg04610667 chr7:75704037 NA 0.35 6.2 0.32 1.61e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs738322 0.967 rs133013 chr22:38570912 C/T cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg06466757 chr4:1255808 NA 0.35 5.93 0.31 7.24e-9 Obesity-related traits; LIHC cis rs8060686 0.565 rs75286242 chr16:68145798 C/T cg05110241 chr16:68378359 PRMT7 -0.6 -6.64 -0.34 1.21e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 23.89 0.79 7.09e-75 Prudent dietary pattern; LIHC cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg22105103 chr4:187893119 NA 0.35 8.63 0.42 2.4e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 0.964 rs1768802 chr1:46547868 A/G cg03146154 chr1:46216737 IPP -0.45 -7.27 -0.37 2.52e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11792861 0.926 rs72607170 chr9:111836941 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.67 0.42 1.82e-16 Menarche (age at onset); LIHC cis rs2228479 0.618 rs17233623 chr16:89811209 C/T cg00800038 chr16:89945340 TCF25 -0.63 -9.45 -0.45 5.73e-19 Skin colour saturation; LIHC cis rs2455799 0.574 rs2455800 chr3:15701589 T/G cg16303742 chr3:15540471 COLQ -0.34 -5.78 -0.3 1.65e-8 Mean platelet volume; LIHC cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg19774624 chr17:42201019 HDAC5 0.79 12.14 0.55 1.86e-28 Total body bone mineral density; LIHC cis rs651907 0.557 rs7651406 chr3:101393296 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.47 -6.75 -0.34 6.39e-11 Colorectal cancer; LIHC cis rs8108269 0.868 rs10422601 chr19:46159414 G/C cg13320842 chr19:46175254 GIPR 0.41 7.7 0.38 1.5e-13 Type 2 diabetes; LIHC cis rs12971120 0.504 rs11665154 chr18:72147006 A/C cg25817165 chr18:72167213 CNDP2 -0.47 -8.09 -0.4 1.07e-14 Refractive error; LIHC cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.16 18.07 0.7 1.04e-51 Gut microbiome composition (summer); LIHC cis rs881375 0.678 rs7031752 chr9:123663482 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.47 0.33 3.46e-10 Rheumatoid arthritis; LIHC cis rs116248771 0.739 rs73156437 chr3:158359284 T/C cg16708174 chr3:158430962 RARRES1 0.49 6.43 0.33 4.26e-10 diarrhoeal disease at age 2; LIHC trans rs11098499 0.863 rs1155576 chr4:120450159 A/C cg25214090 chr10:38739885 LOC399744 0.59 9.52 0.46 3.1400000000000002e-19 Corneal astigmatism; LIHC cis rs9399135 0.935 rs4273704 chr6:135297520 G/T cg22676075 chr6:135203613 NA 0.4 6.47 0.33 3.48e-10 Red blood cell count; LIHC cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg13409248 chr3:40428643 ENTPD3 -0.4 -6.64 -0.34 1.23e-10 Renal cell carcinoma; LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.68 0.57 1.87e-30 Prudent dietary pattern; LIHC trans rs1005277 0.505 rs200935 chr10:38132810 T/A cg17830980 chr10:43048298 ZNF37B -0.46 -8.85 -0.43 4.65e-17 Extrinsic epigenetic age acceleration; LIHC cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg13126279 chr21:47581558 C21orf56 -0.48 -7.63 -0.38 2.38e-13 Testicular germ cell tumor; LIHC cis rs6598955 0.670 rs4659366 chr1:26542572 G/A cg04990556 chr1:26633338 UBXN11 -0.55 -8.97 -0.44 1.98e-17 Obesity-related traits; LIHC cis rs6942756 0.747 rs598412 chr7:129127736 C/T cg02491457 chr7:128862824 NA 0.55 8.55 0.42 4.08e-16 White matter hyperintensity burden; LIHC cis rs1552244 0.882 rs17050672 chr3:10025463 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.59 -8.3 -0.41 2.5e-15 Alzheimer's disease; LIHC cis rs17376456 0.542 rs10070350 chr5:93103753 C/G cg25358565 chr5:93447407 FAM172A 0.8 7.66 0.38 1.99e-13 Diabetic retinopathy; LIHC cis rs2710642 0.693 rs10168771 chr2:62903187 G/A cg17519650 chr2:63277830 OTX1 0.53 7.6 0.38 2.96e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs11585357 0.895 rs72633828 chr1:17632251 G/A cg08277548 chr1:17600880 PADI3 -0.62 -6.56 -0.33 1.96e-10 Hair shape; LIHC cis rs9814567 1.000 rs11927068 chr3:134266321 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2070488 1.000 rs2276540 chr3:38512507 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.13 0.66 6.33e-44 Electrocardiographic conduction measures; LIHC cis rs4665809 1.000 rs6546766 chr2:26328680 T/C cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs35110281 0.807 rs2838328 chr21:45023234 G/C cg21573476 chr21:45109991 RRP1B -0.53 -10.07 -0.48 4.56e-21 Mean corpuscular volume; LIHC cis rs908922 0.676 rs2146120 chr1:152504200 A/T cg20991723 chr1:152506922 NA 0.44 6.75 0.34 6.36e-11 Hair morphology; LIHC cis rs10751667 0.666 rs7395321 chr11:940280 C/T cg06064525 chr11:970664 AP2A2 -0.55 -14.97 -0.63 2.48e-39 Alzheimer's disease (late onset); LIHC cis rs10870270 0.956 rs10870293 chr10:133771413 G/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.7 -0.57 1.55e-30 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg13271783 chr10:134563150 INPP5A -0.54 -6.8 -0.34 4.77e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2439831 0.850 rs3742982 chr15:44176681 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.53 0.33 2.39e-10 Lung cancer in ever smokers; LIHC cis rs1552244 0.608 rs3732962 chr3:10048951 T/C cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs72781680 1.000 rs72798418 chr2:24188922 A/G cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.29 -5.86 -0.3 1.07e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs546131 0.600 rs525202 chr11:34821948 A/C cg06937548 chr11:34938143 PDHX;APIP 0.51 6.78 0.34 5.42e-11 Lung disease severity in cystic fibrosis; LIHC cis rs12701220 0.655 rs34696066 chr7:1140919 C/T cg09177884 chr7:1199841 ZFAND2A -0.53 -6.1 -0.31 2.9e-9 Bronchopulmonary dysplasia; LIHC cis rs5769707 0.521 rs5769719 chr22:50062101 G/A cg01652190 chr22:50026171 C22orf34 -0.29 -6.3 -0.32 9.2e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs56235845 0.694 rs4532376 chr5:176774403 G/A cg16006841 chr5:176797999 RGS14 0.58 7.92 0.39 3.33e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs240764 0.658 rs12194255 chr6:101168439 G/A cg12253828 chr6:101329408 ASCC3 -0.4 -6.28 -0.32 1.03e-9 Neuroticism; LIHC cis rs2412488 1.000 rs6554100 chr4:54240108 C/T cg22241045 chr4:54363911 LNX1 -0.45 -7.1 -0.36 7.36e-12 DNA methylation (variation); LIHC cis rs7712401 0.755 rs1545697 chr5:122102277 T/C cg18764291 chr5:122110994 SNX2 0.36 6.12 0.31 2.56e-9 Mean platelet volume; LIHC cis rs17428076 0.874 rs17581361 chr2:172682612 T/G cg13550731 chr2:172543902 DYNC1I2 0.38 6.21 0.32 1.55e-9 Myopia; LIHC cis rs7726839 0.540 rs4957083 chr5:659343 T/C cg09021430 chr5:549028 NA -0.42 -8.57 -0.42 3.6e-16 Obesity-related traits; LIHC cis rs77106637 0.860 rs1552224 chr11:72433098 A/C cg03713592 chr11:72463424 ARAP1 1.14 10.04 0.48 6e-21 Type 2 diabetes; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.5 7.04 0.36 1.04e-11 Height; LIHC cis rs11098699 0.821 rs1562063 chr4:124204110 G/A cg09941581 chr4:124220074 SPATA5 0.32 6.38 0.33 5.62e-10 Mosquito bite size; LIHC cis rs11958404 1.000 rs11958404 chr5:157410278 A/T cg05962755 chr5:157440814 NA 0.88 10.05 0.48 5.43e-21 IgG glycosylation; LIHC cis rs796364 0.806 rs11684895 chr2:201009026 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 12.68 0.57 1.83e-30 Alzheimer's disease; LIHC cis rs10078 0.515 rs1053299 chr5:470760 G/A cg07599136 chr5:415885 AHRR 0.78 12.78 0.57 7.81e-31 Fat distribution (HIV); LIHC cis rs6582630 0.593 rs11182590 chr12:38574274 A/T cg26384229 chr12:38710491 ALG10B 0.4 6.18 0.32 1.8e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs6684514 1.000 rs11264464 chr1:156250887 T/G cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs12586317 0.547 rs2038254 chr14:35462134 C/T cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.04e-32 Psoriasis; LIHC cis rs9640161 0.659 rs11975886 chr7:150010362 G/A cg10018233 chr7:150070692 REPIN1 0.5 8.19 0.4 5.27e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs9916302 0.904 rs68178216 chr17:37526241 A/C cg00129232 chr17:37814104 STARD3 0.4 6.34 0.32 7.08e-10 Glomerular filtration rate (creatinine); LIHC cis rs2115630 1.000 rs2115630 chr15:85364516 C/T cg12501888 chr15:85177176 SCAND2 -0.49 -7.44 -0.37 7.98e-13 P wave terminal force; LIHC trans rs3783890 1.000 rs17129006 chr14:93788891 A/G cg02802420 chr16:69363236 PDF;COG8 0.32 6.32 0.32 8.12e-10 Body mass index; LIHC cis rs912057 0.582 rs1294412 chr6:6739854 A/G cg06612196 chr6:6737390 NA 0.55 10.16 0.48 2.32e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs7528419 1.000 rs646776 chr1:109818530 C/T cg20569855 chr1:109824440 PSRC1 0.5 6.53 0.33 2.42e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs1008375 1.000 rs7694020 chr4:17682597 C/T cg02297831 chr4:17616191 MED28 0.43 6.95 0.35 1.9e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7772486 0.790 rs2253764 chr6:146199881 T/A cg23711669 chr6:146136114 FBXO30 0.64 11.58 0.53 2.23e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7100689 0.577 rs7901663 chr10:82153488 C/G cg01528321 chr10:82214614 TSPAN14 0.65 9.82 0.47 3.35e-20 Post bronchodilator FEV1; LIHC cis rs7772486 0.597 rs7746618 chr6:146281367 T/C cg05347473 chr6:146136440 FBXO30 -0.47 -6.77 -0.34 5.64e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs769267 0.965 rs2965198 chr19:19473030 A/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.59 -9.12 -0.44 6.57e-18 Tonsillectomy; LIHC cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 11.44 0.53 7.19e-26 Platelet count; LIHC cis rs11758351 1.000 rs11754744 chr6:26202605 G/A cg03854865 chr6:26224070 HIST1H3E 0.62 6.86 0.35 3.24e-11 Gout;Renal underexcretion gout; LIHC cis rs72627509 0.904 rs7687767 chr4:57824932 C/T cg26694713 chr4:57773883 REST -0.65 -9.28 -0.45 2.02e-18 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2760061 0.583 rs708110 chr1:228190805 T/A cg02753203 chr1:228287806 NA 0.72 10.34 0.49 5.45e-22 Diastolic blood pressure; LIHC cis rs875971 0.545 rs1796217 chr7:66085918 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.79 -0.34 4.99e-11 Aortic root size; LIHC cis rs9596863 0.898 rs9568898 chr13:54317030 G/T ch.13.53330881F chr13:54432880 NA 0.42 5.76 0.3 1.85e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs11785693 0.862 rs17435612 chr8:4987896 C/T cg26367366 chr8:4980734 NA -0.56 -6.18 -0.32 1.79e-9 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs911555 0.519 rs8014069 chr14:104004311 A/C cg24130564 chr14:104152367 KLC1 -0.38 -5.97 -0.31 6.07e-9 Intelligence (multi-trait analysis); LIHC cis rs801193 1.000 rs2003301 chr7:66147656 G/C cg00343986 chr7:65444356 GUSB -0.4 -5.99 -0.31 5.21e-9 Aortic root size; LIHC cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.67e-21 Intelligence (multi-trait analysis); LIHC trans rs2243480 1.000 rs313809 chr7:65499983 G/A cg10756647 chr7:56101905 PSPH 1.09 13.42 0.59 2.91e-33 Diabetic kidney disease; LIHC cis rs1801251 1.000 rs1446308 chr2:233639309 T/C cg08000102 chr2:233561755 GIGYF2 0.76 11.56 0.53 2.56e-26 Coronary artery disease; LIHC cis rs1799949 0.965 rs6503726 chr17:41284742 T/C cg25072359 chr17:41440525 NA 0.37 5.96 0.31 6.42e-9 Menopause (age at onset); LIHC cis rs6066825 0.590 rs729663 chr20:47304306 C/T cg18078177 chr20:47281410 PREX1 -0.47 -8.18 -0.4 5.51e-15 Colorectal cancer; LIHC cis rs28830936 1.000 rs17676742 chr15:41903048 A/G cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.78 -0.3 1.67e-8 Diastolic blood pressure; LIHC cis rs832187 0.776 rs854622 chr3:63862842 C/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.48 -7.05 -0.36 9.91e-12 Schizophrenia; LIHC cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg00149659 chr3:10157352 C3orf10 0.69 7.22 0.36 3.4e-12 Alzheimer's disease; LIHC cis rs1707322 1.000 rs12133129 chr1:46373348 C/T cg06784218 chr1:46089804 CCDC17 0.34 6.09 0.31 3.11e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs10506458 0.915 rs12426308 chr12:63405778 C/T cg22491629 chr6:157744540 C6orf35 -0.59 -10.72 -0.5 2.7e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs1577917 1.000 rs6923148 chr6:86767786 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.25 0.41 3.49e-15 Response to antipsychotic treatment; LIHC cis rs7208859 0.673 rs73277984 chr17:29196133 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6723226 0.699 rs376914 chr2:32508393 G/C cg02381751 chr2:32503542 YIPF4 0.75 11.19 0.52 5.45e-25 Intelligence (multi-trait analysis); LIHC cis rs2115630 0.936 rs8033459 chr15:85253258 C/T cg12501888 chr15:85177176 SCAND2 -0.5 -7.65 -0.38 2.13e-13 P wave terminal force; LIHC cis rs16828019 0.777 rs12748235 chr1:41466221 G/A cg03387723 chr1:41708464 SCMH1 -0.45 -6.66 -0.34 1.07e-10 Intelligence (multi-trait analysis); LIHC cis rs4927850 0.881 rs7630489 chr3:195753401 T/C cg01181863 chr3:195395398 SDHAP2 -0.5 -6.5 -0.33 2.81e-10 Pancreatic cancer; LIHC cis rs1008375 1.000 rs10027755 chr4:17615954 G/C cg02297831 chr4:17616191 MED28 0.49 7.57 0.38 3.54e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4763879 0.739 rs12582584 chr12:9824138 T/G cg26689682 chr12:9723402 NA -0.36 -5.88 -0.3 9.53e-9 Type 1 diabetes; LIHC cis rs4843747 0.749 rs12102841 chr16:88072574 C/G cg07560587 chr16:88016574 BANP -0.36 -5.8 -0.3 1.48e-8 Menopause (age at onset); LIHC trans rs17685 0.796 rs3757594 chr7:75678644 G/A cg19862616 chr7:65841803 NCRNA00174 -0.91 -18.54 -0.71 1.34e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg07424592 chr7:64974309 NA 0.83 9.7 0.46 7.94e-20 Diabetic kidney disease; LIHC cis rs2257205 0.667 rs6503879 chr17:56888183 T/A cg05425664 chr17:57184151 TRIM37 -0.6 -6.61 -0.34 1.5e-10 Pancreatic cancer; LIHC cis rs1707322 1.000 rs785507 chr1:46541558 C/T cg06784218 chr1:46089804 CCDC17 -0.4 -7.17 -0.36 4.54e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7605378 0.528 rs1704191 chr2:200816393 C/A cg23649088 chr2:200775458 C2orf69 0.58 8.35 0.41 1.7e-15 Osteoporosis; LIHC cis rs79839061 0.656 rs28662837 chr4:879776 G/A cg12601576 chr4:906860 GAK -0.61 -5.73 -0.3 2.22e-8 Intelligence (multi-trait analysis); LIHC cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg26939375 chr7:64535504 NA -0.46 -7.03 -0.36 1.16e-11 Aortic root size; LIHC cis rs7520050 0.966 rs1768803 chr1:46546208 T/C cg03146154 chr1:46216737 IPP -0.37 -6.18 -0.32 1.8e-9 Red blood cell count;Reticulocyte count; LIHC trans rs875971 0.660 rs2013222 chr7:66035936 C/G cg26939375 chr7:64535504 NA -0.41 -6.55 -0.33 2.11e-10 Aortic root size; LIHC trans rs1005277 0.505 rs200939 chr10:38139483 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.86 0.35 3.29e-11 Extrinsic epigenetic age acceleration; LIHC cis rs1538970 0.924 rs4660855 chr1:45899795 A/G cg15605315 chr1:45957053 TESK2 -0.44 -5.71 -0.3 2.43e-8 Platelet count; LIHC cis rs6665290 0.904 rs10495273 chr1:227183359 T/G cg10327440 chr1:227177885 CDC42BPA -1.19 -31.38 -0.86 1.02e-102 Myeloid white cell count; LIHC cis rs2012796 0.956 rs6574646 chr14:81819809 A/G cg02996355 chr14:81879375 NA 0.45 6.79 0.34 5.04e-11 Night sleep phenotypes; LIHC cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.12 0.31 2.59e-9 Menopause (age at onset); LIHC cis rs7208859 0.614 rs9914534 chr17:29202664 G/A cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg12064134 chr16:90016061 DEF8 -0.44 -5.79 -0.3 1.61e-8 Skin colour saturation; LIHC cis rs8180040 0.903 rs13094438 chr3:47277885 G/A cg27129171 chr3:47204927 SETD2 0.68 11.61 0.53 1.76e-26 Colorectal cancer; LIHC trans rs8073060 0.586 rs8074800 chr17:33979148 A/G cg19694781 chr19:47549865 TMEM160 1.21 13.52 0.59 1.13e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs4714291 0.926 rs847771 chr6:40048586 T/C cg02267698 chr19:7991119 CTXN1 0.39 6.23 0.32 1.4e-9 Strep throat; LIHC trans rs2727020 0.576 rs1814175 chr11:49559172 T/C cg03929089 chr4:120376271 NA -0.88 -16.77 -0.67 1.77e-46 Coronary artery disease; LIHC cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg16145915 chr7:1198662 ZFAND2A -0.4 -10.18 -0.48 1.89e-21 Longevity;Endometriosis; LIHC cis rs7107174 1.000 rs7104222 chr11:78007169 G/A cg02023728 chr11:77925099 USP35 0.5 9.62 0.46 1.52e-19 Testicular germ cell tumor; LIHC cis rs4631830 0.900 rs10763534 chr10:51534920 C/T cg20129853 chr10:51489980 NA -0.4 -8.62 -0.42 2.56e-16 Prostate-specific antigen levels; LIHC trans rs3960554 0.808 rs61303167 chr7:75671175 G/T cg19862616 chr7:65841803 NCRNA00174 0.6 8.37 0.41 1.45e-15 Eotaxin levels; LIHC cis rs700651 0.789 rs62277902 chr2:198879443 T/A cg10820045 chr2:198174542 NA -0.46 -6.89 -0.35 2.66e-11 Intracranial aneurysm; LIHC cis rs6952808 0.595 rs3800917 chr7:2167939 A/G cg20295408 chr7:1910781 MAD1L1 0.39 5.74 0.3 2.07e-8 Bipolar disorder and schizophrenia; LIHC cis rs367615 0.506 rs2914680 chr5:108787146 A/G cg17395555 chr5:108820864 NA -0.32 -6.68 -0.34 9.58e-11 Colorectal cancer (SNP x SNP interaction); LIHC cis rs6539267 0.741 rs10861572 chr12:106688576 A/G cg00173435 chr12:106696525 TCP11L2 -0.59 -7.97 -0.4 2.32e-14 Tourette syndrome; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.76 -0.34 6.07e-11 Menopause (age at onset); LIHC cis rs9640161 0.742 rs11983355 chr7:150016697 A/C cg21361702 chr7:150065534 REPIN1 0.46 6.4 0.33 5.1e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg23172400 chr8:95962367 TP53INP1 -0.37 -8.08 -0.4 1.11e-14 Type 2 diabetes; LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.51 -0.38 5.16e-13 Lymphocyte counts; LIHC trans rs208520 1.000 rs208536 chr6:66963440 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.69 -0.34 9.29e-11 Exhaled nitric oxide output; LIHC trans rs916888 0.773 rs169201 chr17:44790203 A/G cg07870213 chr5:140052090 DND1 1.03 10.49 0.49 1.71e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg26354017 chr1:205819088 PM20D1 0.84 12.17 0.55 1.49e-28 Menarche (age at onset); LIHC cis rs7100689 0.784 rs10887838 chr10:82161380 G/A cg00277334 chr10:82204260 NA -0.57 -7.36 -0.37 1.38e-12 Post bronchodilator FEV1; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg16822855 chr3:40428330 ENTPD3 -0.33 -6.23 -0.32 1.36e-9 Renal cell carcinoma; LIHC cis rs8005677 1.000 rs1951119 chr14:23388326 A/C cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs1144333 0.655 rs1417402 chr1:76437196 C/T cg03433033 chr1:76189801 ACADM 0.55 7.57 0.38 3.42e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs7131987 0.650 rs11050188 chr12:29473108 A/C cg12903224 chr12:29470962 FAR2 -0.41 -6.51 -0.33 2.68e-10 QT interval; LIHC cis rs1862618 0.671 rs2591970 chr5:56232595 T/C cg24531977 chr5:56204891 C5orf35 0.54 7.88 0.39 4.38e-14 Initial pursuit acceleration; LIHC cis rs2120019 1.000 rs7175720 chr15:75348962 C/G cg06012730 chr15:75315579 PPCDC 0.34 6.38 0.33 5.61e-10 Blood trace element (Zn levels); LIHC cis rs11864453 0.713 rs3764312 chr16:72125733 A/C cg16558253 chr16:72132732 DHX38 -0.51 -8.13 -0.4 8.1e-15 Fibrinogen levels; LIHC cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg22907277 chr7:1156413 C7orf50 0.41 5.85 0.3 1.13e-8 Longevity;Endometriosis; LIHC cis rs561341 0.830 rs7218801 chr17:30217778 A/G cg13647721 chr17:30228624 UTP6 -0.75 -7.35 -0.37 1.46e-12 Hip circumference adjusted for BMI; LIHC cis rs4911259 0.552 rs13038881 chr20:31468113 T/C cg13636640 chr20:31349939 DNMT3B -0.62 -10.82 -0.51 1.14e-23 Inflammatory bowel disease; LIHC cis rs801193 0.844 rs732465 chr7:65998450 T/C cg18876405 chr7:65276391 NA 0.4 7.13 0.36 6.02e-12 Aortic root size; LIHC cis rs1185460 0.565 rs10892325 chr11:118912702 T/C cg23280166 chr11:118938394 VPS11 -0.43 -5.88 -0.3 9.62e-9 Coronary artery disease; LIHC cis rs4423214 1.000 rs1044482 chr11:71155171 C/T cg05163923 chr11:71159392 DHCR7 0.9 14.26 0.61 1.52e-36 Vitamin D levels; LIHC cis rs8072100 0.967 rs2317826 chr17:45730899 C/T cg08085267 chr17:45401833 C17orf57 -0.56 -8.39 -0.41 1.28e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs208520 0.690 rs1100981 chr6:66852052 T/C cg07460842 chr6:66804631 NA -0.74 -8.34 -0.41 1.87e-15 Exhaled nitric oxide output; LIHC cis rs17685 0.735 rs11763339 chr7:75761541 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14577476 chr17:49337432 MBTD1;UTP18 -0.45 -6.72 -0.34 7.8e-11 Cognitive function; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.75 0.62 1.85e-38 Prudent dietary pattern; LIHC cis rs12477438 0.765 rs7605218 chr2:99593080 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.2 -0.41 4.82e-15 Chronic sinus infection; LIHC cis rs8062405 0.698 rs8046545 chr16:28915217 G/A cg00204512 chr16:28754710 NA -0.37 -6.44 -0.33 4.15e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC cis rs9326248 0.954 rs8521 chr11:117067699 C/T cg11861562 chr11:117069780 TAGLN 0.49 8.02 0.4 1.73e-14 Blood protein levels; LIHC cis rs1005277 0.522 rs200943 chr10:38148730 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.6 -0.56 3.54e-30 Extrinsic epigenetic age acceleration; LIHC cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg27297192 chr10:134578999 INPP5A 0.53 7.42 0.37 9.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs765787 0.530 rs11858988 chr15:45522114 T/C cg25801113 chr15:45476975 SHF 0.38 6.51 0.33 2.69e-10 Uric acid levels; LIHC cis rs62158211 0.955 rs7556815 chr2:114085785 G/A cg17784749 chr2:114082611 LOC440839 0.59 7.43 0.37 8.73e-13 Sleep duration (oversleepers vs undersleepers);Sleep traits (multi-trait analysis);Sleep duration; LIHC cis rs7223966 1.000 rs9893348 chr17:61676534 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 6.72 0.34 7.55e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2439831 0.681 rs484846 chr15:43600803 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.9 16.85 0.67 8.05e-47 Lung cancer in ever smokers; LIHC cis rs12478296 1.000 rs55767645 chr2:242999350 G/A cg06360820 chr2:242988706 NA -0.95 -12.04 -0.55 4.32e-28 Obesity-related traits; LIHC cis rs798554 0.836 rs13243214 chr7:2817455 G/T cg19346786 chr7:2764209 NA -0.45 -6.79 -0.34 4.9e-11 Height; LIHC cis rs6121246 0.567 rs6060399 chr20:30220823 C/T cg13852791 chr20:30311386 BCL2L1 0.75 6.59 0.34 1.66e-10 Mean corpuscular hemoglobin; LIHC trans rs61931739 0.517 rs12816252 chr12:34067693 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.82 0.35 4.04e-11 Morning vs. evening chronotype; LIHC cis rs6977660 0.891 rs10226962 chr7:19819464 T/C cg07541023 chr7:19748670 TWISTNB 0.36 5.73 0.3 2.19e-8 Thyroid stimulating hormone; LIHC cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.97 11.37 0.52 1.3e-25 Alzheimer's disease; LIHC trans rs2073499 0.935 rs2624836 chr3:50208868 A/G cg21659725 chr3:3221576 CRBN -0.63 -6.53 -0.33 2.41e-10 Schizophrenia; LIHC cis rs4727027 0.870 rs1534196 chr7:148790591 G/A cg23583168 chr7:148888333 NA -0.7 -9.9 -0.47 1.7e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs1799949 0.930 rs2298861 chr17:41176831 G/A cg23758822 chr17:41437982 NA 0.93 17.2 0.68 3.13e-48 Menopause (age at onset); LIHC cis rs7223966 1.000 rs9903897 chr17:61716705 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.23 0.36 3.16e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs748404 0.556 rs574856 chr15:43460834 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.37 -5.91 -0.3 8.46e-9 Lung cancer; LIHC cis rs3096299 0.900 rs3114867 chr16:89428967 A/C cg01788221 chr16:89496183 ANKRD11 -0.38 -6.07 -0.31 3.39e-9 Multiple myeloma (IgH translocation); LIHC cis rs7572733 0.534 rs1983359 chr2:198805098 C/T cg00792783 chr2:198669748 PLCL1 0.46 6.86 0.35 3.19e-11 Dermatomyositis; LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.04 -0.31 4.12e-9 Total body bone mineral density; LIHC cis rs16958440 0.867 rs80106524 chr18:44676639 G/A cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs7089973 0.604 rs17663670 chr10:116596269 A/C cg03647239 chr10:116582469 FAM160B1 -0.44 -6.47 -0.33 3.37e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2645694 0.626 rs2703119 chr4:77823640 C/T cg03477792 chr4:77819574 ANKRD56 0.58 8.48 0.42 7e-16 Emphysema distribution in smoking; LIHC trans rs6598955 0.671 rs12139514 chr1:26575939 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC cis rs600806 0.778 rs2787015 chr1:110009434 A/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.74 -0.3 2.14e-8 Intelligence (multi-trait analysis); LIHC cis rs2976388 1.000 rs2920295 chr8:143764937 A/G cg06565975 chr8:143823917 SLURP1 -0.3 -5.74 -0.3 2.1e-8 Urinary tract infection frequency; LIHC cis rs2033711 0.870 rs4801583 chr19:58918405 A/G cg13877915 chr19:58951672 ZNF132 0.57 8.72 0.43 1.26e-16 Uric acid clearance; LIHC cis rs9309473 0.607 rs7574291 chr2:73594941 A/G cg20560298 chr2:73613845 ALMS1 -0.47 -7.54 -0.38 4.27e-13 Metabolite levels; LIHC cis rs7635838 0.785 rs2594972 chr3:11397417 A/G cg00170343 chr3:11313890 ATG7 0.47 7.49 0.38 5.87e-13 HDL cholesterol; LIHC cis rs6788895 1.000 rs16862842 chr3:150484844 A/G cg09723797 chr3:150481914 SIAH2 0.8 10.9 0.51 5.87e-24 Breast cancer; LIHC trans rs2018683 0.835 rs7782264 chr7:28978986 A/G cg19402173 chr7:128379420 CALU 0.43 6.81 0.35 4.29e-11 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs6546550 0.935 rs2872075 chr2:70068635 G/T cg02498382 chr2:70120550 SNRNP27 -0.38 -6.16 -0.32 2.08e-9 Prevalent atrial fibrillation; LIHC cis rs1499614 1.000 rs2659911 chr7:66158420 G/A cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg12516959 chr21:47718080 NA -0.37 -6.02 -0.31 4.5e-9 Testicular germ cell tumor; LIHC cis rs614226 1.000 rs580016 chr12:120933977 T/C cg01236616 chr12:121019343 POP5 -1.11 -11.31 -0.52 2.16e-25 Type 1 diabetes nephropathy; LIHC cis rs12808519 0.688 rs35759009 chr11:69583722 A/G cg19831575 chr11:69590090 FGF4 0.5 7.01 0.35 1.26e-11 Urate levels in overweight individuals; LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg06873352 chr17:61820015 STRADA -0.47 -7.02 -0.35 1.19e-11 Height; LIHC trans rs12478296 1.000 rs55732177 chr2:243040006 C/T cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.95e-15 Obesity-related traits; LIHC cis rs1568889 0.838 rs7131379 chr11:28085789 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 13.81 0.6 8.58e-35 Bipolar disorder; LIHC cis rs826838 0.616 rs10880754 chr12:38628154 C/T cg26384229 chr12:38710491 ALG10B -0.52 -7.3 -0.37 2e-12 Heart rate; LIHC cis rs151997 0.830 rs27282 chr5:50198970 G/A cg06027927 chr5:50259733 NA 0.44 6.55 0.33 2.12e-10 Callous-unemotional behaviour; LIHC cis rs6500602 0.647 rs3747600 chr16:4586222 A/G cg08645402 chr16:4508243 NA 0.42 7.44 0.37 8.45e-13 Schizophrenia; LIHC cis rs3789045 0.560 rs3747634 chr1:204411063 C/T cg17419461 chr1:204415978 PIK3C2B 0.52 8.04 0.4 1.48e-14 Educational attainment (college completion); LIHC cis rs561341 0.700 rs2074101 chr17:30228656 G/A cg13647721 chr17:30228624 UTP6 0.78 8.98 0.44 1.88e-17 Hip circumference adjusted for BMI; LIHC cis rs244293 1.000 rs244286 chr17:53232594 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.48 -7.02 -0.35 1.22e-11 Menarche (age at onset); LIHC cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg11502198 chr6:26597334 ABT1 0.64 10.12 0.48 3.23e-21 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.765 rs9457259 chr6:167444281 C/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.11 -0.4 8.87e-15 Crohn's disease; LIHC cis rs16944613 0.510 rs11636571 chr15:91143857 A/G cg26821196 chr15:91095069 CRTC3 0.32 5.99 0.31 5.4e-9 Colorectal cancer; LIHC cis rs4474465 0.920 rs7947824 chr11:78223731 C/G cg27205649 chr11:78285834 NARS2 0.42 6.3 0.32 8.98e-10 Alzheimer's disease (survival time); LIHC cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg12379764 chr21:47803548 PCNT -0.59 -8.99 -0.44 1.77e-17 Testicular germ cell tumor; LIHC trans rs2681424 1.000 rs4974394 chr3:121756249 A/G cg03946530 chr15:65596423 NA -0.48 -6.22 -0.32 1.46e-9 Multiple sclerosis; LIHC cis rs7089973 0.668 rs10885622 chr10:116643844 C/T cg03647239 chr10:116582469 FAM160B1 0.45 6.32 0.32 8.03e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1982963 1.000 rs904061 chr14:52504624 T/C cg10843707 chr14:52510701 NID2 -0.44 -7.58 -0.38 3.3e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2072499 0.932 rs3001790 chr1:156165290 T/G cg25208724 chr1:156163844 SLC25A44 0.94 15.84 0.65 9.26e-43 Testicular germ cell tumor; LIHC trans rs877282 0.898 rs36064821 chr10:760952 C/T cg22713356 chr15:30763199 NA 1.37 12.19 0.55 1.23e-28 Uric acid levels; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg16103275 chr6:290800 DUSP22 0.5 6.55 0.33 2.16e-10 Menopause (age at onset); LIHC cis rs7945718 0.967 rs2241857 chr11:12815831 C/T cg25843174 chr11:12811716 TEAD1 -0.34 -7.89 -0.39 4.14e-14 Educational attainment (years of education); LIHC cis rs1008375 1.000 rs10032326 chr4:17630717 A/T cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.67e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1983891 1.000 rs9296365 chr6:41535379 A/G cg15051332 chr6:41514432 FOXP4 0.42 5.76 0.3 1.83e-8 Prostate cancer; LIHC cis rs6542838 0.702 rs4851177 chr2:99535188 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.54 -0.33 2.19e-10 Fear of minor pain; LIHC cis rs1385374 0.858 rs11059930 chr12:129297860 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.75 0.39 1.09e-13 Systemic lupus erythematosus; LIHC cis rs3741404 0.665 rs12418535 chr11:63910980 A/G cg18225595 chr11:63971243 STIP1 0.68 10.9 0.51 5.88e-24 Platelet count; LIHC cis rs9611565 0.729 rs169362 chr22:41827589 G/C cg03806693 chr22:41940476 POLR3H 0.56 7.36 0.37 1.36e-12 Vitiligo; LIHC cis rs10864907 0.553 rs7578034 chr2:113718077 C/T cg12858261 chr2:113808755 IL1F8 0.35 5.99 0.31 5.38e-9 Pulmonary function; LIHC cis rs4742903 0.935 rs1580014 chr9:106933625 A/C cg14250997 chr9:106856677 SMC2 0.35 5.91 0.3 8.19e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs4423214 1.000 rs12422045 chr11:71154820 C/T cg05163923 chr11:71159392 DHCR7 0.92 14.6 0.62 7.04e-38 Vitamin D levels; LIHC cis rs9473924 0.505 rs34793301 chr6:50859462 G/T cg14470998 chr6:50812995 TFAP2B 1.02 9.21 0.45 3.31e-18 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25733915 chr17:40829168 PLEKHH3 0.44 6.93 0.35 2.11e-11 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06966887 chr5:443603 EXOC3;C5orf55 0.46 6.68 0.34 9.49e-11 Pancreatic cancer; LIHC cis rs2033711 0.840 rs3764533 chr19:58929194 A/G cg26874164 chr19:58962979 ZNF324B 0.44 6.05 0.31 3.86e-9 Uric acid clearance; LIHC cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg00343986 chr7:65444356 GUSB 0.44 6.26 0.32 1.18e-9 Calcium levels; LIHC trans rs7569426 0.676 rs2098566 chr2:34405818 A/G cg05775492 chr16:86258717 NA 0.24 6.45 0.33 3.83e-10 Subjective well-being; LIHC cis rs67460515 0.563 rs4679672 chr3:160901020 G/A cg03342759 chr3:160939853 NMD3 -0.62 -9.4 -0.45 8.36e-19 Parkinson's disease; LIHC cis rs4901869 0.966 rs60800733 chr14:59337778 A/G cg02291164 chr14:59296302 NA 0.48 6.09 0.31 2.98e-9 Panic disorder; LIHC cis rs7309 0.935 rs11884495 chr2:162059969 A/T cg21518248 chr2:162101506 NA 0.46 7.09 0.36 7.91e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs3818285 0.679 rs612155 chr10:111630731 C/G cg00817464 chr10:111662876 XPNPEP1 0.65 11.33 0.52 1.83e-25 Superior crus of antihelix expression; LIHC cis rs9814567 1.000 rs4974493 chr3:134219993 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.86 -0.3 1.06e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4906332 0.811 rs2296487 chr14:103996205 T/C cg04998671 chr14:104000505 TRMT61A -0.59 -7.83 -0.39 6.16e-14 Coronary artery disease; LIHC cis rs1577917 0.917 rs35738006 chr6:86646309 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.35 -0.37 1.43e-12 Response to antipsychotic treatment; LIHC cis rs6933660 0.720 rs6914656 chr6:151753421 C/G cg10883421 chr6:151773342 RMND1;C6orf211 0.61 10.11 0.48 3.46e-21 Menarche (age at onset); LIHC cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg27286337 chr10:134555280 INPP5A 0.84 12.64 0.56 2.54e-30 Migraine; LIHC cis rs9837602 0.529 rs1688774 chr3:99521108 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.83 -0.3 1.26e-8 Breast cancer; LIHC cis rs738321 0.757 rs4820315 chr22:38518731 C/T cg25457927 chr22:38595422 NA -0.33 -7.54 -0.38 4.2e-13 Breast cancer; LIHC cis rs7772486 0.790 rs2265919 chr6:146221753 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.84 0.3 1.2e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs78456975 1.000 rs11891809 chr2:1566001 A/G cg01028140 chr2:1542097 TPO -0.47 -5.77 -0.3 1.76e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs7408868 1.000 rs7408868 chr19:15285679 G/C cg14696996 chr19:15285081 NOTCH3 0.55 7.2 0.36 3.87e-12 Pulse pressure; LIHC cis rs7520050 0.872 rs2486445 chr1:46605369 C/T cg06787764 chr1:46668870 C1orf190;POMGNT1 0.39 5.77 0.3 1.75e-8 Red blood cell count;Reticulocyte count; LIHC trans rs10213084 0.920 rs56271575 chr4:147498323 A/C cg18061433 chr10:21435895 C10orf113;NEBL 0.47 6.12 0.31 2.63e-9 Heart rate; LIHC cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg02475777 chr4:1388615 CRIPAK -0.54 -7.72 -0.39 1.28e-13 Longevity; LIHC cis rs2032447 0.530 rs9356996 chr6:26008487 C/A cg12310025 chr6:25882481 NA -0.52 -6.75 -0.34 6.45e-11 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.9 0.57 2.79e-31 Prudent dietary pattern; LIHC cis rs12980942 1.000 rs2241720 chr19:41829309 C/G cg25627403 chr19:41769009 HNRNPUL1 0.56 6.81 0.35 4.29e-11 Coronary artery disease; LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.3e-14 Height; LIHC cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg02290350 chr8:58132656 NA 0.53 9.48 0.46 4.32e-19 Developmental language disorder (linguistic errors); LIHC cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg08132940 chr7:1081526 C7orf50 -0.71 -6.21 -0.32 1.52e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7945705 0.692 rs11042149 chr11:9010737 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -8.74 -0.43 1.08e-16 Hemoglobin concentration; LIHC cis rs589448 0.902 rs2603090 chr12:69777188 G/A cg19645103 chr12:69753606 YEATS4 -0.4 -5.96 -0.31 6.15e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7927771 0.793 rs12803525 chr11:47413475 G/A cg20307385 chr11:47447363 PSMC3 -0.46 -6.07 -0.31 3.49e-9 Subjective well-being; LIHC cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.84e-10 Diabetic kidney disease; LIHC trans rs916888 0.773 rs199535 chr17:44822662 A/G cg13957321 chr17:43675089 NA 0.5 7.88 0.39 4.56e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg12463550 chr7:65579703 CRCP 0.71 7.44 0.37 8.23e-13 Diabetic kidney disease; LIHC cis rs2354432 0.943 rs6660219 chr1:146691404 A/T cg25205988 chr1:146714368 CHD1L 0.93 12.82 0.57 5.52e-31 Mitochondrial DNA levels; LIHC cis rs7224314 1.000 rs7219229 chr17:65380171 C/T cg01507342 chr17:65387096 PITPNC1 -0.47 -5.95 -0.31 6.74e-9 Diisocyanate-induced asthma; LIHC cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg27572855 chr1:25598939 RHD 0.41 8.86 0.43 4.43e-17 Erythrocyte sedimentation rate; LIHC cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.85 0.3 1.14e-8 Calcium levels; LIHC cis rs965469 1.000 rs2236106 chr20:3278410 A/C cg25506879 chr20:3388711 C20orf194 -0.55 -6.74 -0.34 6.9e-11 IFN-related cytopenia; LIHC cis rs61990749 0.544 rs11628888 chr14:78161506 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.6 -10.01 -0.48 7.29e-21 Fibroblast growth factor basic levels; LIHC cis rs2197308 0.740 rs11182967 chr12:37935140 A/C cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg10424330 chr16:71894309 ZNF821;ATXN1L 0.41 6.22 0.32 1.47e-9 Immature fraction of reticulocytes; LIHC cis rs763014 1.000 rs763014 chr16:675680 T/C cg09263875 chr16:632152 PIGQ 0.61 10.64 0.5 4.85e-23 Height; LIHC cis rs589448 0.900 rs588493 chr12:69751986 G/A cg14784868 chr12:69753453 YEATS4 1.0 23.05 0.78 1.35e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs62005083 0.541 rs61059815 chr14:74536465 A/T cg05179529 chr14:74551516 LIN52;ALDH6A1 0.5 6.55 0.33 2.11e-10 Mean corpuscular volume; LIHC cis rs6782228 0.585 rs2811492 chr3:128356279 A/G cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs9640161 0.789 rs1464752 chr7:150021284 C/T cg21361702 chr7:150065534 REPIN1 0.44 5.99 0.31 5.31e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs593982 0.925 rs603509 chr11:65507605 C/T cg08755490 chr11:65554678 OVOL1 -0.5 -7.88 -0.39 4.35e-14 Atopic dermatitis; LIHC cis rs4764487 0.735 rs3181291 chr12:6341499 C/T cg08284733 chr12:6341482 CD9 0.35 6.22 0.32 1.45e-9 Mean platelet volume; LIHC cis rs2268241 0.877 rs17887186 chr21:34779202 G/A cg14850771 chr21:34775459 IFNGR2 0.91 13.79 0.6 1.02e-34 Obesity-related traits; LIHC cis rs611744 0.967 rs598477 chr8:109187874 G/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs765787 0.530 rs1706834 chr15:45517854 G/A cg24006582 chr15:45444508 DUOX1 -0.54 -7.73 -0.39 1.22e-13 Uric acid levels; LIHC cis rs6964587 0.935 rs28412174 chr7:91577245 T/G cg17063962 chr7:91808500 NA -1.01 -19.13 -0.72 5.63e-56 Breast cancer; LIHC cis rs9818758 0.607 rs35283189 chr3:49113668 T/C cg07636037 chr3:49044803 WDR6 -0.84 -8.52 -0.42 5.33e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9393692 0.875 rs6939589 chr6:26289203 C/T cg05868516 chr6:26286170 HIST1H4H -0.43 -6.51 -0.33 2.67e-10 Educational attainment; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg08219700 chr8:58056026 NA 0.52 7.14 0.36 5.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg25072359 chr17:41440525 NA 0.39 6.16 0.32 2.01e-9 Menopause (age at onset); LIHC cis rs3106136 0.649 rs28463907 chr4:95302595 A/G cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs2370759 1.000 rs11594459 chr10:32561858 A/C cg05361325 chr10:32636312 EPC1 -0.5 -6.18 -0.32 1.87e-9 Sexual dysfunction (female); LIHC cis rs1538970 1.000 rs61791368 chr1:45867944 T/C cg24296786 chr1:45957014 TESK2 -0.51 -7.35 -0.37 1.49e-12 Platelet count; LIHC cis rs11711311 1.000 rs2603793 chr3:113496418 A/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.47 9.06 0.44 9.93e-18 IgG glycosylation; LIHC cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2073300 1.000 rs6132621 chr20:23442180 C/T cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs79243044 0.786 rs16932549 chr11:5560909 C/T cg00219956 chr16:30794205 ZNF629 0.42 6.05 0.31 3.84e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs7827545 0.644 rs7386524 chr8:135534005 T/C cg09855544 chr8:135498122 ZFAT -0.49 -8.3 -0.41 2.41e-15 Hypertension (SNP x SNP interaction); LIHC cis rs7903847 0.642 rs11189191 chr10:99148796 T/C cg20016023 chr10:99160130 RRP12 -0.41 -6.49 -0.33 2.99e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs8077889 0.645 rs1230396 chr17:41843029 A/C cg26893861 chr17:41843967 DUSP3 -1.14 -21.79 -0.76 1.28e-66 Triglycerides; LIHC cis rs1348850 0.837 rs12619074 chr2:178472336 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.67 9.03 0.44 1.26e-17 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6963495 0.745 rs2392749 chr7:105182605 A/G cg19920283 chr7:105172520 RINT1 0.75 8.57 0.42 3.54e-16 Bipolar disorder (body mass index interaction); LIHC cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.88 0.3 9.88e-9 Electroencephalogram traits; LIHC cis rs7520050 0.966 rs2486447 chr1:46545724 G/A cg03146154 chr1:46216737 IPP -0.38 -6.26 -0.32 1.12e-9 Red blood cell count;Reticulocyte count; LIHC cis rs763014 0.966 rs35642938 chr16:642249 T/C cg08989290 chr16:615782 NHLRC4 0.31 5.99 0.31 5.42e-9 Height; LIHC cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg00166722 chr3:10149974 C3orf24 0.52 6.05 0.31 3.8e-9 Alzheimer's disease; LIHC trans rs783540 0.869 rs783533 chr15:83250186 C/T cg18393722 chr15:85113863 UBE2QP1 -0.37 -6.42 -0.33 4.57e-10 Schizophrenia; LIHC cis rs4319547 0.626 rs11057882 chr12:122875046 A/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.19 -0.36 3.98e-12 Body mass index; LIHC cis rs7647973 0.710 rs34890793 chr3:49619493 C/T cg03060546 chr3:49711283 APEH 0.6 6.91 0.35 2.34e-11 Menarche (age at onset); LIHC cis rs644799 0.965 rs2950522 chr11:95524719 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.55 0.69 1.29e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs763121 0.853 rs3747174 chr22:39069181 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC trans rs11165623 0.582 rs10875023 chr1:97012386 T/C cg10631902 chr5:14652156 NA -0.25 -6.22 -0.32 1.43e-9 Hip circumference;Waist circumference; LIHC cis rs986417 1.000 rs6573313 chr14:60961299 A/G cg27398547 chr14:60952738 C14orf39 0.72 8.41 0.41 1.11e-15 Gut microbiota (bacterial taxa); LIHC cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg03351412 chr1:154909251 PMVK 0.7 10.35 0.49 5.21e-22 Prostate cancer; LIHC cis rs4788570 0.697 rs6499540 chr16:71822250 A/C cg06353428 chr16:71660113 MARVELD3 1.33 14.27 0.61 1.38e-36 Intelligence (multi-trait analysis); LIHC cis rs904251 0.861 rs2776877 chr6:37487135 G/A cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.48e-9 Cognitive performance; LIHC cis rs765787 0.530 rs2433229 chr15:45515235 C/A cg25801113 chr15:45476975 SHF 0.38 6.43 0.33 4.18e-10 Uric acid levels; LIHC cis rs7264396 0.790 rs6060516 chr20:34214368 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -9.91 -0.47 1.62e-20 Total cholesterol levels; LIHC cis rs240764 0.817 rs12199888 chr6:101154419 T/A cg09795085 chr6:101329169 ASCC3 -0.52 -7.15 -0.36 5.31e-12 Neuroticism; LIHC cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg18357526 chr6:26021779 HIST1H4A -0.59 -7.07 -0.36 8.73e-12 Blood metabolite levels; LIHC cis rs12922040 1.000 rs2075516 chr16:15869525 C/T cg08214245 chr16:15829296 MYH11 0.31 6.07 0.31 3.37e-9 Serum uric acid levels in response to allopurinol in gout; LIHC cis rs9303401 0.614 rs3803752 chr17:56540267 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.98 13.34 0.58 5.74e-33 Cognitive test performance; LIHC cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg11764359 chr7:65958608 NA -0.68 -9.24 -0.45 2.64e-18 Aortic root size; LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg03874509 chr1:107600012 PRMT6 0.7 10.95 0.51 4.01e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg12379764 chr21:47803548 PCNT 0.54 8.12 0.4 8.75e-15 Testicular germ cell tumor; LIHC cis rs2549003 1.000 rs2070726 chr5:131821738 C/A cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs2637266 1.000 rs2395385 chr10:78341125 G/A cg18941641 chr10:78392320 NA 0.3 6.41 0.33 4.93e-10 Pulmonary function; LIHC cis rs12477438 0.520 rs720229 chr2:99704273 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.81 13.77 0.6 1.3e-34 Chronic sinus infection; LIHC cis rs4684776 0.676 rs35975472 chr3:11292653 T/G cg00170343 chr3:11313890 ATG7 -0.48 -6.49 -0.33 3.08e-10 Small vessel stroke; LIHC cis rs9916302 0.861 rs4795377 chr17:37669056 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.41 -0.59 3.06e-33 Glomerular filtration rate (creatinine); LIHC cis rs473651 0.935 rs558924 chr2:239339511 A/G cg18131467 chr2:239335373 ASB1 0.8 12.53 0.56 6.95e-30 Multiple system atrophy; LIHC cis rs4604732 0.536 rs4433437 chr1:247636580 A/T cg02104434 chr1:247694406 LOC148824;OR2C3 0.24 5.77 0.3 1.75e-8 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC trans rs2504916 0.830 rs2504934 chr6:160781666 A/G cg27088830 chr6:166401018 C6orf176;LOC441177 -0.45 -6.28 -0.32 1.02e-9 Response to hepatitis C treatment; LIHC trans rs9914544 1.000 rs6502677 chr17:18803658 A/G cg04702396 chr17:15466718 FAM18B2 0.46 6.95 0.35 1.82e-11 Educational attainment (years of education); LIHC cis rs12701220 0.553 rs34062359 chr7:1139076 C/T cg00990874 chr7:1149470 C7orf50 -0.58 -5.87 -0.3 1e-8 Bronchopulmonary dysplasia; LIHC cis rs1005277 0.579 rs1780116 chr10:38526621 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.24 -0.32 1.29e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg03264133 chr6:25882463 NA 0.55 7.53 0.38 4.43e-13 Blood metabolite levels; LIHC cis rs12291225 0.679 rs1043237 chr11:14289053 A/T cg19336497 chr11:14380999 RRAS2 -0.63 -12.34 -0.56 3.43e-29 Sense of smell; LIHC cis rs244293 0.965 rs244362 chr17:53188917 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.58 -0.38 3.26e-13 Menarche (age at onset); LIHC cis rs769267 0.965 rs2074550 chr19:19387743 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC trans rs1005277 0.579 rs2474572 chr10:38385316 A/G cg17830980 chr10:43048298 ZNF37B -0.53 -10.74 -0.5 2.25e-23 Extrinsic epigenetic age acceleration; LIHC cis rs763121 0.819 rs5750658 chr22:39060917 C/T cg06022373 chr22:39101656 GTPBP1 0.66 11.49 0.53 4.72e-26 Menopause (age at onset); LIHC cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.632 rs1607254 chr2:172626552 A/G cg13550731 chr2:172543902 DYNC1I2 0.64 11.56 0.53 2.48e-26 Schizophrenia; LIHC cis rs7582180 0.817 rs1437967 chr2:100929072 C/G cg14675211 chr2:100938903 LONRF2 0.54 8.13 0.4 8.09e-15 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.846 rs3775100 chr4:1225106 T/C cg20887711 chr4:1340912 KIAA1530 0.44 6.27 0.32 1.1e-9 Obesity-related traits; LIHC cis rs6840360 0.593 rs1429558 chr4:152685406 A/T cg22705602 chr4:152727874 NA -0.4 -8.41 -0.41 1.13e-15 Intelligence (multi-trait analysis); LIHC cis rs703842 0.585 rs10877022 chr12:58223937 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.67 9.58 0.46 2.13e-19 Multiple sclerosis; LIHC cis rs2839186 1.000 rs2839181 chr21:47685939 A/G cg12379764 chr21:47803548 PCNT -0.58 -8.37 -0.41 1.54e-15 Testicular germ cell tumor; LIHC cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg12292205 chr6:26970375 C6orf41 -0.39 -6.76 -0.34 5.97e-11 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg02034447 chr16:89574710 SPG7 0.45 7.06 0.36 9.24e-12 Multiple myeloma (IgH translocation); LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.78 0.54 4.13e-27 Prudent dietary pattern; LIHC cis rs763121 0.853 rs5750626 chr22:38977890 G/C cg14440974 chr22:39074834 NA -0.44 -7.0 -0.35 1.36e-11 Menopause (age at onset); LIHC cis rs910316 0.664 rs2098252 chr14:75492732 T/C cg11812906 chr14:75593930 NEK9 0.74 13.64 0.59 3.84e-34 Height; LIHC cis rs9549367 0.789 rs8001506 chr13:113867153 A/C cg18105134 chr13:113819100 PROZ -0.57 -10.2 -0.48 1.68e-21 Platelet distribution width; LIHC cis rs780096 1.000 rs780096 chr2:27741072 C/G cg22903471 chr2:27725779 GCKR -0.31 -5.84 -0.3 1.2e-8 Total body bone mineral density; LIHC cis rs11671005 0.735 rs11667591 chr19:58937637 G/A cg25952890 chr19:58913133 NA 0.71 7.73 0.39 1.18e-13 Mean platelet volume; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg24209194 chr3:40518798 ZNF619 0.63 9.66 0.46 1.09e-19 Renal cell carcinoma; LIHC cis rs6754311 0.509 rs10188066 chr2:136539513 G/A cg25344623 chr2:136566232 LCT 0.33 6.23 0.32 1.41e-9 Mosquito bite size; LIHC cis rs6500602 0.964 rs2304633 chr16:4496973 T/A cg08645402 chr16:4508243 NA 0.4 7.49 0.38 6.05e-13 Schizophrenia; LIHC cis rs7945705 0.747 rs1980428 chr11:9010497 A/G cg12365402 chr11:9010492 NRIP3 0.29 7.72 0.39 1.3e-13 Hemoglobin concentration; LIHC cis rs7523273 0.925 rs12132780 chr1:207999605 C/T cg22525895 chr1:207977042 MIR29B2 -0.69 -10.59 -0.5 7.74e-23 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02084834 chr2:201983708 CFLAR 0.44 6.52 0.33 2.53e-10 Pancreatic cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg09148975 chr1:38274245 C1orf122;YRDC -0.53 -6.14 -0.32 2.26e-9 Systolic blood pressure; LIHC trans rs1814175 0.803 rs11040451 chr11:49650639 C/T cg15704280 chr7:45808275 SEPT13 -0.99 -20.8 -0.75 1.1e-62 Height; LIHC cis rs796364 0.616 rs2689765 chr2:200696352 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.59 6.14 0.32 2.26e-9 Schizophrenia; LIHC cis rs9457247 0.765 rs2237276 chr6:167442115 C/T cg07741184 chr6:167504864 NA 0.32 7.4 0.37 1.08e-12 Crohn's disease; LIHC cis rs588177 0.613 rs3782101 chr11:64131280 A/G cg18375707 chr11:64034959 PLCB3 -0.36 -5.82 -0.3 1.37e-8 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs2404602 0.684 rs11072602 chr15:76873467 T/C cg23625390 chr15:77176239 SCAPER -0.55 -9.04 -0.44 1.18e-17 Blood metabolite levels; LIHC cis rs1552244 0.882 rs13063098 chr3:10009919 G/A cg08888203 chr3:10149979 C3orf24 0.5 6.26 0.32 1.16e-9 Alzheimer's disease; LIHC cis rs6500602 0.727 rs11644481 chr16:4581002 T/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.49 7.52 0.38 4.84e-13 Schizophrenia; LIHC trans rs7674212 0.541 rs2045746 chr4:104083578 A/C cg16471864 chr4:38666270 KLF3;FLJ13197 0.45 6.64 0.34 1.22e-10 Type 2 diabetes; LIHC cis rs10870270 0.956 rs6557 chr10:133781449 C/T cg26149184 chr10:133730230 NA 0.47 7.44 0.37 7.99e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6088590 1.000 rs6087623 chr20:33317662 C/G cg06115741 chr20:33292138 TP53INP2 0.59 8.53 0.42 4.83e-16 Coronary artery disease; LIHC cis rs7208859 0.673 rs7211776 chr17:29120196 T/G cg14067834 chr17:29058358 SUZ12P 0.65 6.69 0.34 9.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11122272 0.735 rs2808603 chr1:231537738 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.84e-22 Hemoglobin concentration; LIHC cis rs1580019 0.539 rs11769109 chr7:32571352 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.41 5.84 0.3 1.19e-8 Cognitive ability; LIHC cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs2153535 0.580 rs9406170 chr6:8514153 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.77 0.54 4.4e-27 Motion sickness; LIHC cis rs743757 0.816 rs6792502 chr3:50531201 C/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.47 7.07 0.36 8.54e-12 Diastolic blood pressure; LIHC cis rs7249142 0.549 rs1858846 chr19:19281187 T/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.4 -6.65 -0.34 1.13e-10 IgG glycosylation; LIHC cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg04944784 chr2:26401820 FAM59B -0.72 -8.85 -0.43 4.84e-17 Gut microbiome composition (summer); LIHC cis rs35110281 0.805 rs2838318 chr21:44991825 G/A cg21573476 chr21:45109991 RRP1B -0.5 -9.68 -0.46 9.68e-20 Mean corpuscular volume; LIHC cis rs6952808 0.823 rs10950448 chr7:1966492 G/C cg19016816 chr7:1267987 NA 0.27 5.79 0.3 1.55e-8 Bipolar disorder and schizophrenia; LIHC cis rs8078723 1.000 rs1042658 chr17:38173902 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.12 -0.44 6.77e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg02290350 chr8:58132656 NA 0.4 8.21 0.41 4.42e-15 Developmental language disorder (linguistic errors); LIHC cis rs7937890 0.559 rs2575853 chr11:14533963 T/C cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC cis rs7224737 1.000 rs2240009 chr17:40283142 C/G cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC trans rs12753920 0.703 rs2391116 chr1:92622569 A/G cg15668468 chr10:118892869 VAX1 0.42 6.12 0.31 2.58e-9 Systemic lupus erythematosus; LIHC cis rs7772486 0.790 rs6926076 chr6:146232804 C/T cg23711669 chr6:146136114 FBXO30 -0.64 -11.16 -0.52 7.22e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg06656553 chr16:89960601 TCF25 0.44 6.01 0.31 4.81e-9 Skin colour saturation; LIHC cis rs2236918 0.687 rs2797600 chr1:242029331 C/T cg17736920 chr1:242011382 EXO1 0.42 6.28 0.32 1.05e-9 Menopause (age at onset); LIHC cis rs6430585 0.528 rs3099429 chr2:136655582 T/A cg07169764 chr2:136633963 MCM6 0.99 15.05 0.63 1.21e-39 Corneal structure; LIHC cis rs3790645 1.000 rs444482 chr1:26890648 C/G cg17456097 chr1:26900765 RPS6KA1 0.4 5.84 0.3 1.2e-8 Glucose homeostasis traits; LIHC cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg11644478 chr21:40555479 PSMG1 -0.38 -6.14 -0.31 2.35e-9 Menarche (age at onset); LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg00656387 chr3:40428638 ENTPD3 0.5 8.29 0.41 2.68e-15 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04722168 chr1:26324647 PAFAH2 0.46 6.56 0.33 1.95e-10 Pancreatic cancer; LIHC cis rs4975709 0.569 rs2353583 chr5:1858834 G/C cg15595755 chr5:1867978 NA 0.41 7.96 0.4 2.55e-14 Cardiovascular disease risk factors; LIHC cis rs6570726 1.000 rs1935615 chr6:145921117 G/T cg23711669 chr6:146136114 FBXO30 0.54 9.24 0.45 2.67e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs1055129 0.655 rs7216615 chr17:73833910 T/C cg08125733 chr17:73851984 WBP2 0.51 8.19 0.41 5.19e-15 White matter hyperintensity burden; LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.63 0.46 1.44e-19 Height; LIHC cis rs7927771 0.832 rs67116452 chr11:47385194 G/A cg20135002 chr11:47629003 NA -0.51 -8.75 -0.43 9.91e-17 Subjective well-being; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23183521 chr12:57146030 PRIM1 0.49 6.67 0.34 1.04e-10 Lung function (FEV1/FVC); LIHC cis rs9640161 0.702 rs1962004 chr7:150020381 G/A cg17279839 chr7:150038598 RARRES2 0.57 11.64 0.53 1.29e-26 Blood protein levels;Circulating chemerin levels; LIHC cis rs2540917 0.765 rs2244030 chr2:60612238 A/G cg00543073 chr2:60773386 BCL11A -0.32 -6.33 -0.32 7.64e-10 Mean corpuscular volume; LIHC cis rs17685 0.712 rs10235738 chr7:75773460 G/A cg16684958 chr7:75615977 POR 0.4 6.57 0.33 1.87e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7116495 0.609 rs1548348 chr11:71750917 A/G cg26138937 chr11:71823887 C11orf51 -1.34 -10.79 -0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC cis rs10924970 0.805 rs2789363 chr1:235519034 A/T cg26050004 chr1:235667680 B3GALNT2 0.42 6.19 0.32 1.68e-9 Asthma; LIHC cis rs2841277 0.708 rs2582533 chr14:105398787 G/C cg15352829 chr14:105391018 PLD4 -0.44 -8.91 -0.43 3.08e-17 Rheumatoid arthritis; LIHC cis rs6952808 0.771 rs10950415 chr7:1914477 A/G cg04267008 chr7:1944627 MAD1L1 -0.58 -8.78 -0.43 7.71e-17 Bipolar disorder and schizophrenia; LIHC trans rs11039798 0.588 rs1847640 chr11:49004025 C/T cg15704280 chr7:45808275 SEPT13 0.61 6.7 0.34 8.5e-11 Axial length; LIHC cis rs8141529 0.732 rs2269577 chr22:29196757 G/C cg02153584 chr22:29168773 CCDC117 0.57 9.28 0.45 1.92e-18 Lymphocyte counts; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs4742903 0.933 rs10820608 chr9:106890840 A/G cg14250997 chr9:106856677 SMC2 0.42 7.44 0.37 8.21e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.02 0.6 1.31e-35 Prudent dietary pattern; LIHC trans rs2288327 0.673 rs35504893 chr2:179421294 C/T cg14011486 chr1:26737247 LIN28 0.53 7.37 0.37 1.29e-12 Atrial fibrillation; LIHC cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg11890956 chr21:40555474 PSMG1 1.06 15.48 0.64 2.49e-41 Cognitive function; LIHC cis rs9733 0.596 rs12085275 chr1:150650265 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Tonsillectomy; LIHC cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg11062466 chr8:58055876 NA 0.44 6.53 0.33 2.34e-10 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.753 rs1859791 chr7:75786043 T/C cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9381040 1.000 rs2093395 chr6:41155026 C/G cg25110423 chr6:41068646 NFYA;LOC221442 0.36 5.93 0.31 7.41e-9 Alzheimer's disease (late onset); LIHC cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg11764359 chr7:65958608 NA -0.58 -5.98 -0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs4853012 0.793 rs6723185 chr2:74344884 T/A cg05890377 chr2:74357713 NA 0.62 12.63 0.56 2.76e-30 Gestational age at birth (maternal effect); LIHC trans rs57221529 0.766 rs28563961 chr5:554498 C/G cg25482853 chr8:67687455 SGK3 0.67 6.69 0.34 8.97e-11 Lung disease severity in cystic fibrosis; LIHC trans rs11760633 0.607 rs7777233 chr7:1831671 C/T cg00395210 chr12:48592465 NA 0.35 6.11 0.31 2.79e-9 Coronary artery disease; LIHC cis rs116095464 0.558 rs12173244 chr5:269524 G/A cg22496380 chr5:211416 CCDC127 -1.01 -10.2 -0.48 1.62e-21 Breast cancer; LIHC cis rs249954 0.512 rs42873 chr16:23694732 C/G cg05131483 chr16:23706242 ERN2 0.35 5.82 0.3 1.38e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6547741 0.935 rs2384626 chr2:27773648 A/G cg22903471 chr2:27725779 GCKR 0.34 5.8 0.3 1.53e-8 Oral cavity cancer; LIHC trans rs11098499 0.698 rs4422403 chr4:120258194 C/T cg25214090 chr10:38739885 LOC399744 0.44 7.32 0.37 1.75e-12 Corneal astigmatism; LIHC cis rs12744310 0.887 rs12040046 chr1:41797583 C/T cg03962019 chr1:41807865 NA -0.36 -5.87 -0.3 1.02e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs801193 1.000 rs62466794 chr7:66191579 G/A cg11764359 chr7:65958608 NA 0.71 10.72 0.5 2.6e-23 Aortic root size; LIHC cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg20818283 chr2:191399100 TMEM194B -0.44 -6.04 -0.31 4e-9 Pulse pressure; LIHC cis rs10870270 0.830 rs11146269 chr10:133761820 G/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.78 -0.57 7.66e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs11792861 0.926 rs7470160 chr9:111844246 C/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.64e-16 Menarche (age at onset); LIHC cis rs765787 0.530 rs1706831 chr15:45516230 T/C cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs965469 1.000 rs2281494 chr20:3235494 A/G cg25506879 chr20:3388711 C20orf194 -0.56 -6.95 -0.35 1.82e-11 IFN-related cytopenia; LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg00960700 chr17:80709150 TBCD 0.36 5.98 0.31 5.64e-9 Glycated hemoglobin levels; LIHC cis rs16828019 0.852 rs12742379 chr1:41526381 A/G cg20697417 chr1:41786797 NA 0.31 5.93 0.31 7.37e-9 Intelligence (multi-trait analysis); LIHC cis rs963731 0.649 rs378698 chr2:39316301 T/C cg04010122 chr2:39346883 SOS1 -0.68 -6.03 -0.31 4.15e-9 Corticobasal degeneration; LIHC cis rs7872515 0.824 rs7858659 chr9:94822146 A/C cg01248375 chr9:94877805 SPTLC1 0.51 6.89 0.35 2.77e-11 Bipolar disorder and schizophrenia; LIHC cis rs16866061 0.515 rs11695326 chr2:225415134 A/G cg22509189 chr2:225307070 NA -0.51 -7.49 -0.38 6.06e-13 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs950169 0.580 rs11634322 chr15:85172209 C/T cg12863693 chr15:85201151 NMB 0.49 7.03 0.36 1.13e-11 Schizophrenia; LIHC cis rs1003719 0.762 rs11701556 chr21:38455153 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.06 0.55 3.76e-28 Eye color traits; LIHC cis rs1816752 0.870 rs9581027 chr13:24997928 G/A cg22771759 chr13:24902376 NA 0.32 6.49 0.33 3.03e-10 Obesity-related traits; LIHC cis rs1538970 1.000 rs11211101 chr1:45849311 C/G cg24296786 chr1:45957014 TESK2 -0.48 -7.13 -0.36 6.05e-12 Platelet count; LIHC cis rs77861329 1.000 rs164639 chr3:52210872 A/G cg08692210 chr3:52188851 WDR51A -0.74 -7.53 -0.38 4.59e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs25645 0.823 rs12453334 chr17:38153473 C/T cg17467752 chr17:38218738 THRA -0.51 -8.67 -0.42 1.71e-16 Myeloid white cell count; LIHC cis rs5769765 0.862 rs138870 chr22:50209737 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -8.47 -0.42 7.33e-16 Schizophrenia; LIHC cis rs1348850 0.914 rs3902850 chr2:178315899 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 13.9 0.6 4.07e-35 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4819052 0.851 rs9977178 chr21:46664531 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.72 0.39 1.28e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10838687 0.736 rs2279238 chr11:47282024 C/T cg26139080 chr11:47293733 MADD -0.42 -5.95 -0.31 6.57e-9 Proinsulin levels; LIHC cis rs11671005 0.610 rs3816329 chr19:59058693 G/A cg25952890 chr19:58913133 NA 0.66 6.71 0.34 7.94e-11 Mean platelet volume; LIHC cis rs12477438 0.765 rs6737257 chr2:99683330 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs1801251 0.752 rs709938 chr2:233746457 C/T cg08000102 chr2:233561755 GIGYF2 -0.72 -10.67 -0.5 3.81e-23 Coronary artery disease; LIHC cis rs9814567 0.896 rs13089566 chr3:134349710 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.58 9.47 0.46 4.84e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7197653 0.519 rs55757091 chr16:68323654 G/A cg09835421 chr16:68378352 PRMT7 -0.63 -7.18 -0.36 4.35e-12 Magnesium levels; LIHC cis rs9399137 0.507 rs13064 chr6:135287533 A/G cg24558204 chr6:135376177 HBS1L 0.6 10.23 0.48 1.34e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg11644478 chr21:40555479 PSMG1 0.86 10.84 0.51 9.63e-24 Cognitive function; LIHC cis rs1348850 0.914 rs9789582 chr2:178330173 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.89 14.13 0.61 5.07e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2730245 0.959 rs2527201 chr7:158738611 G/T cg24397884 chr7:158709396 WDR60 -0.41 -6.18 -0.32 1.85e-9 Height; LIHC cis rs1371867 0.846 rs1660332 chr8:101309490 A/G cg06636551 chr8:101224915 SPAG1 0.51 9.21 0.45 3.45e-18 Atrioventricular conduction; LIHC cis rs9640161 0.789 rs1464751 chr7:150021282 C/T cg21361702 chr7:150065534 REPIN1 0.45 6.05 0.31 3.72e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs11628318 0.614 rs12588817 chr14:103089210 G/A cg12046867 chr14:103022105 NA -0.42 -6.65 -0.34 1.15e-10 Platelet count; LIHC cis rs7578199 0.752 rs746675 chr2:242193706 T/A cg19372975 chr2:242212901 HDLBP -0.6 -5.83 -0.3 1.26e-8 Chronic lymphocytic leukemia; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg07537819 chr6:156886127 NA 0.39 6.23 0.32 1.4e-9 Bilirubin levels; LIHC cis rs9905704 0.647 rs12943705 chr17:57097047 T/C cg12560992 chr17:57184187 TRIM37 -0.66 -9.89 -0.47 1.88e-20 Testicular germ cell tumor; LIHC cis rs7945705 0.747 rs2568045 chr11:9004060 T/C cg12365402 chr11:9010492 NRIP3 -0.29 -7.81 -0.39 7.25e-14 Hemoglobin concentration; LIHC cis rs67311347 1.000 rs2887995 chr3:40409029 C/G cg24209194 chr3:40518798 ZNF619 0.42 5.97 0.31 6.06e-9 Renal cell carcinoma; LIHC cis rs4474465 1.000 rs7935292 chr11:78169885 C/G cg27205649 chr11:78285834 NARS2 -0.37 -5.78 -0.3 1.68e-8 Alzheimer's disease (survival time); LIHC cis rs1843834 0.539 rs10177898 chr2:225437552 C/T cg22509189 chr2:225307070 NA -0.83 -11.63 -0.53 1.45e-26 IgE levels in asthmatics (D.p. specific); LIHC cis rs67981189 0.593 rs2810109 chr14:71419892 A/T cg15816911 chr14:71606274 NA -0.42 -6.75 -0.34 6.4e-11 Schizophrenia; LIHC cis rs3020736 0.500 rs2413672 chr22:42513261 C/T cg04733989 chr22:42467013 NAGA -0.64 -9.18 -0.44 4.09e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs10870270 0.784 rs10430614 chr10:133748640 C/T cg17892150 chr10:133769511 PPP2R2D 0.63 11.68 0.53 9.66e-27 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9818758 0.607 rs34580506 chr3:49113713 C/A cg00383909 chr3:49044727 WDR6 0.85 7.04 0.36 1.09e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9300255 0.596 rs7304782 chr12:123719444 A/G cg00376283 chr12:123451042 ABCB9 -0.67 -10.25 -0.48 1.15e-21 Neutrophil percentage of white cells; LIHC cis rs2439831 0.681 rs28594657 chr15:43588888 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.82 9.08 0.44 8.54e-18 Lung cancer in ever smokers; LIHC cis rs1008375 0.932 rs7697329 chr4:17657853 C/A cg16339924 chr4:17578868 LAP3 0.53 6.94 0.35 2e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2070488 0.965 rs13093640 chr3:38487176 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC cis rs7726839 0.561 rs4957048 chr5:583442 G/A cg09021430 chr5:549028 NA -0.4 -8.48 -0.42 6.68e-16 Obesity-related traits; LIHC cis rs921968 0.643 rs563268 chr2:219372912 T/G cg17980119 chr2:219472607 PLCD4 0.36 6.14 0.31 2.34e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs13118159 0.836 rs2276903 chr4:1343405 A/G cg20887711 chr4:1340912 KIAA1530 0.55 8.3 0.41 2.36e-15 Longevity; LIHC cis rs1198430 0.925 rs1767148 chr1:23765472 A/G cg13183780 chr1:23809682 ASAP3 -0.54 -7.73 -0.39 1.2e-13 Total cholesterol levels; LIHC cis rs7223966 1.000 rs11079508 chr17:61750066 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.47 0.33 3.37e-10 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15044954 chr7:89874365 C7orf63 0.41 6.26 0.32 1.18e-9 Cognitive function; LIHC cis rs919433 1.000 rs1429414 chr2:198162430 C/T cg03934865 chr2:198174659 NA -0.59 -9.5 -0.46 3.88e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg23649088 chr2:200775458 C2orf69 0.58 8.32 0.41 2.18e-15 Osteoporosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14275779 chr17:40830236 PLEKHH3 0.41 6.77 0.34 5.55e-11 Cognitive function; LIHC cis rs4819052 0.851 rs8126930 chr21:46671715 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.56 8.29 0.41 2.68e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10792665 0.898 rs4511296 chr11:82678953 A/C cg24227371 chr11:82718527 RAB30 -0.31 -7.15 -0.36 5.21e-12 Obesity-related traits; LIHC cis rs34779708 0.966 rs7077242 chr10:35481965 A/C cg04310649 chr10:35416472 CREM 0.43 5.82 0.3 1.37e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg17971929 chr21:40555470 PSMG1 -0.51 -7.68 -0.38 1.66e-13 Cognitive function; LIHC cis rs2292096 0.925 rs72746845 chr1:200711624 C/A cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -5.98 -0.31 5.56e-9 Epilepsy; LIHC cis rs1670533 1.000 rs10003009 chr4:1050849 G/A cg27284194 chr4:1044797 NA 0.6 8.83 0.43 5.59e-17 Recombination rate (females); LIHC cis rs853679 0.517 rs56310871 chr6:28044482 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs7131987 0.621 rs3782506 chr12:29445422 A/C cg12903224 chr12:29470962 FAR2 0.43 7.04 0.36 1.06e-11 QT interval; LIHC cis rs2228479 0.850 rs11640188 chr16:89807732 C/T cg04013166 chr16:89971882 TCF25 0.49 6.07 0.31 3.31e-9 Skin colour saturation; LIHC cis rs1348850 0.651 rs4893931 chr2:178228212 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.78 12.13 0.55 2.05e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg23556447 chr6:90529595 MDN1 -0.52 -6.14 -0.32 2.35e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs597539 0.617 rs598353 chr11:68635770 C/A cg06028808 chr11:68637592 NA 0.43 5.85 0.3 1.16e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs11931598 0.513 rs3857170 chr4:7003366 A/T cg02503808 chr4:7069936 GRPEL1 0.41 6.42 0.33 4.68e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs1005277 0.579 rs2103938 chr10:38493998 T/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7.19e-18 Extrinsic epigenetic age acceleration; LIHC cis rs2404602 0.692 rs34287706 chr15:76942402 A/C cg03037974 chr15:76606532 NA 0.74 14.44 0.62 3.1e-37 Blood metabolite levels; LIHC cis rs77637988 0.631 rs7587385 chr2:48600691 T/G cg15846641 chr2:48541264 FOXN2 0.59 8.0 0.4 1.97e-14 Joint mobility (Beighton score); LIHC cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg14004847 chr7:1930337 MAD1L1 -0.53 -7.92 -0.39 3.34e-14 Schizophrenia; LIHC cis rs8060686 0.565 rs36046686 chr16:68122269 T/C cg09835421 chr16:68378352 PRMT7 -0.5 -5.92 -0.3 7.91e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs875971 0.862 rs949930 chr7:65766822 C/G cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs875971 0.862 rs1083554 chr7:65852341 T/C cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs7249142 0.526 rs7256811 chr19:19283551 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.42 -6.99 -0.35 1.48e-11 IgG glycosylation; LIHC cis rs8084351 0.577 rs12457189 chr18:50665754 T/C cg24270629 chr18:50823537 DCC -0.43 -6.39 -0.33 5.46e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9649465 1.000 rs7805759 chr7:123318696 C/A cg03229431 chr7:123269106 ASB15 -0.38 -8.18 -0.4 5.61e-15 Migraine; LIHC cis rs10751667 0.600 rs10751672 chr11:948712 T/C ch.11.42038R chr11:967971 AP2A2 0.54 9.81 0.47 3.52e-20 Alzheimer's disease (late onset); LIHC cis rs6450176 1.000 rs6886510 chr5:53303127 A/G ch.5.1024479R chr5:53302184 ARL15 0.8 14.45 0.62 2.92e-37 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2153535 0.580 rs7741456 chr6:8452424 G/A cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC cis rs2425143 1.000 rs7273815 chr20:34232415 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.14e-8 Blood protein levels; LIHC cis rs11098499 0.874 rs7661020 chr4:120106982 T/C cg09307838 chr4:120376055 NA 0.52 7.74 0.39 1.16e-13 Corneal astigmatism; LIHC cis rs2153535 0.580 rs1889715 chr6:8443475 G/A cg07606381 chr6:8435919 SLC35B3 0.78 11.51 0.53 4.02e-26 Motion sickness; LIHC cis rs4891159 0.790 rs1056714 chr18:74149526 A/G cg24786174 chr18:74118243 ZNF516 -0.73 -13.35 -0.59 5.3e-33 Longevity; LIHC cis rs9916302 0.904 rs7503705 chr17:37669704 A/G cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC cis rs57590327 0.503 rs9880844 chr3:81507217 C/T cg07356753 chr3:81810745 GBE1 0.46 6.84 0.35 3.7e-11 Extraversion; LIHC cis rs1975974 0.511 rs113941161 chr17:21741346 T/C cg18423549 chr17:21743878 NA -0.46 -5.73 -0.3 2.25e-8 Psoriasis; LIHC cis rs17376456 0.877 rs7702521 chr5:93484579 G/T cg25358565 chr5:93447407 FAM172A 1.12 10.24 0.48 1.19e-21 Diabetic retinopathy; LIHC cis rs9457247 0.602 rs4710175 chr6:167467800 A/G cg07741184 chr6:167504864 NA 0.38 8.6 0.42 2.85e-16 Crohn's disease; LIHC cis rs9733 0.596 rs72702552 chr1:150677462 G/A cg18016565 chr1:150552671 MCL1 0.58 11.5 0.53 4.36e-26 Tonsillectomy; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg00802000 chr16:706648 WDR90 -0.37 -6.25 -0.32 1.22e-9 Height; LIHC cis rs7772486 0.806 rs4075696 chr6:146250947 T/C cg05347473 chr6:146136440 FBXO30 -0.36 -6.08 -0.31 3.23e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6938 0.534 rs1133322 chr15:75212357 A/G cg14664628 chr15:75095509 CSK -0.5 -6.49 -0.33 2.96e-10 Breast cancer; LIHC cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg11890956 chr21:40555474 PSMG1 1.08 15.66 0.65 4.6e-42 Cognitive function; LIHC cis rs1577917 0.917 rs12202170 chr6:86590386 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.85 -0.51 8.78e-24 Response to antipsychotic treatment; LIHC cis rs17685 0.753 rs1639609 chr7:75683581 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.14 -0.32 2.31e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9896933 0.775 rs615630 chr17:80730527 T/C cg15664640 chr17:80829946 TBCD 0.57 5.92 0.3 7.79e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs8044868 0.530 rs2287999 chr16:72059149 A/G cg01557791 chr16:72042693 DHODH -0.39 -6.54 -0.33 2.28e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.92 0.57 2.17e-31 Prudent dietary pattern; LIHC cis rs11577318 0.579 rs12131370 chr1:26698430 G/A cg18121669 chr1:26560928 CCDC21 -0.48 -7.15 -0.36 5.44e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9948 0.786 rs55674661 chr2:97473929 A/G cg01990225 chr2:97406019 LMAN2L -0.53 -5.99 -0.31 5.46e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs61041384 0.661 rs75338281 chr12:123507484 G/A cg25930673 chr12:123319894 HIP1R 0.64 5.86 0.3 1.11e-8 Schizophrenia; LIHC cis rs3859192 0.599 rs2227319 chr17:38170845 G/A cg17467752 chr17:38218738 THRA -0.5 -8.63 -0.42 2.34e-16 White blood cell count; LIHC cis rs12744310 1.000 rs72665698 chr1:41775589 T/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7575217 0.643 rs2309996 chr2:101735838 T/G cg23907051 chr2:101730305 TBC1D8 -0.27 -6.06 -0.31 3.52e-9 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; LIHC cis rs2635047 0.967 rs2668779 chr18:44742066 C/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.46 5.92 0.31 7.62e-9 Educational attainment; LIHC cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.18 -0.44 4.28e-18 Bipolar disorder; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg02546883 chr6:157721111 C6orf35 0.38 6.16 0.32 2.09e-9 Body mass index; LIHC cis rs1801251 0.778 rs2250654 chr2:233752376 A/T cg25237894 chr2:233734115 C2orf82 -0.57 -10.96 -0.51 3.6e-24 Coronary artery disease; LIHC cis rs748404 0.660 rs2444251 chr15:43788595 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.91 0.39 3.53e-14 Lung cancer; LIHC cis rs7089973 0.584 rs7908665 chr10:116611337 G/A cg23260525 chr10:116636907 FAM160B1 0.38 7.54 0.38 4.13e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs2727020 0.619 rs11040300 chr11:49269984 C/A cg18944383 chr4:111397179 ENPEP -0.32 -7.07 -0.36 8.91e-12 Coronary artery disease; LIHC cis rs2380220 0.576 rs7751219 chr6:96018915 G/A cg15832292 chr6:96025679 MANEA 0.69 8.54 0.42 4.57e-16 Behavioural disinhibition (generation interaction); LIHC cis rs77633900 0.772 rs157775 chr15:76755641 A/G cg21673338 chr15:77095150 SCAPER -0.52 -5.93 -0.31 7.45e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs6701037 0.782 rs12760073 chr1:175139295 G/T cg00321850 chr1:175162397 KIAA0040 -0.46 -7.28 -0.37 2.27e-12 Alcohol dependence; LIHC cis rs12048904 0.647 rs7528268 chr1:101329295 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.47 6.99 0.35 1.42e-11 Multiple sclerosis; LIHC cis rs4794202 0.534 rs8078688 chr17:45919869 T/C cg10638573 chr17:45915098 SCRN2 0.57 6.22 0.32 1.43e-9 Alzheimer's disease (cognitive decline); LIHC cis rs4713118 0.588 rs200994 chr6:27813813 A/C cg23485639 chr6:28045615 ZNF165 -0.44 -5.82 -0.3 1.34e-8 Parkinson's disease; LIHC cis rs155076 0.666 rs2015241 chr13:21888254 A/G cg11317459 chr13:21872234 NA 1.31 14.02 0.6 1.33e-35 White matter hyperintensity burden; LIHC cis rs288342 0.832 rs288309 chr2:183651433 C/T cg02625481 chr2:183667124 NA -0.29 -5.95 -0.31 6.48e-9 Recurrent major depressive disorder; LIHC cis rs1865721 0.755 rs3813081 chr18:73185096 A/G cg26385618 chr18:73139727 C18orf62 -0.27 -7.14 -0.36 5.69e-12 Intelligence; LIHC cis rs1843834 0.539 rs1494109 chr2:225441833 G/A cg22509189 chr2:225307070 NA -0.83 -11.73 -0.54 6.42e-27 IgE levels in asthmatics (D.p. specific); LIHC cis rs7584330 0.657 rs10190310 chr2:238352282 C/T cg14458575 chr2:238380390 NA 0.39 5.91 0.3 8.47e-9 Prostate cancer; LIHC cis rs55702914 0.809 rs2914982 chr2:198202793 G/C cg10820045 chr2:198174542 NA -0.41 -5.91 -0.3 8.36e-9 Major depression and alcohol dependence; LIHC cis rs3849570 1.000 rs2290081 chr3:81810725 C/T cg07356753 chr3:81810745 GBE1 -0.64 -10.71 -0.5 2.9e-23 Waist circumference;Body mass index; LIHC trans rs1814175 0.715 rs11040586 chr11:49858432 T/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.61 -0.79 8.2e-74 Height; LIHC cis rs2932538 0.885 rs6661642 chr1:113090109 T/C cg22162597 chr1:113214053 CAPZA1 0.69 10.65 0.5 4.45e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs208515 0.560 rs207084 chr6:66776966 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -18.28 -0.7 1.53e-52 Exhaled nitric oxide levels; LIHC cis rs17401966 1.000 rs17411502 chr1:10431158 T/C cg19773385 chr1:10388646 KIF1B -0.51 -8.72 -0.43 1.26e-16 Hepatocellular carcinoma; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg18538332 chr22:24372958 LOC391322 0.57 7.56 0.38 3.73e-13 Urinary 1,3-butadiene metabolite levels in smokers; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg09574498 chr17:48944758 NA 0.41 6.2 0.32 1.61e-9 Alopecia areata; LIHC cis rs477692 1.000 rs538969 chr10:131410608 C/T cg19680672 chr10:131412579 MGMT -0.44 -6.78 -0.34 5.39e-11 Response to temozolomide; LIHC cis rs763121 0.819 rs6001205 chr22:39100264 T/A cg14440974 chr22:39074834 NA -0.46 -7.37 -0.37 1.27e-12 Menopause (age at onset); LIHC cis rs7103648 1.000 rs12292911 chr11:47449072 C/T cg20307385 chr11:47447363 PSMC3 1.03 18.22 0.7 2.47e-52 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs11122272 0.701 rs2790887 chr1:231523724 G/C cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg09455208 chr3:40491958 NA 0.4 8.01 0.4 1.83e-14 Renal cell carcinoma; LIHC cis rs244293 0.965 rs244313 chr17:53214332 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.37 -0.37 1.27e-12 Menarche (age at onset); LIHC cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg12463550 chr7:65579703 CRCP -0.68 -7.09 -0.36 7.77e-12 Diabetic kidney disease; LIHC cis rs9393777 0.623 rs9358948 chr6:26483806 G/A cg12826209 chr6:26865740 GUSBL1 0.69 7.17 0.36 4.61e-12 Intelligence (multi-trait analysis); LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg06138931 chr13:21896616 NA 0.55 9.62 0.46 1.54e-19 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs8067545 0.717 rs34401389 chr17:19989436 A/T cg13482628 chr17:19912719 NA 0.49 8.24 0.41 3.68e-15 Schizophrenia; LIHC cis rs2292096 1.000 rs12736176 chr1:200801028 T/G cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -6.07 -0.31 3.33e-9 Epilepsy; LIHC cis rs4908768 1.000 rs12122666 chr1:8741438 A/C cg20416874 chr1:8611966 RERE -0.52 -7.64 -0.38 2.24e-13 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6691722 0.503 rs3765427 chr1:24705567 G/A cg18323236 chr1:24743029 NIPAL3 0.41 7.49 0.38 5.82e-13 Response to interferon beta in multiple sclerosis; LIHC cis rs12620999 0.838 rs13007071 chr2:238038755 A/G cg23555395 chr2:238036564 NA -0.32 -6.11 -0.31 2.71e-9 Systemic lupus erythematosus; LIHC cis rs4409675 0.527 rs12067053 chr1:28227122 T/G cg23691781 chr1:28212827 C1orf38 0.3 7.34 0.37 1.6e-12 Corneal astigmatism; LIHC cis rs9549367 0.804 rs9549704 chr13:113885187 T/C cg18105134 chr13:113819100 PROZ -0.67 -11.16 -0.52 6.99e-25 Platelet distribution width; LIHC cis rs17125944 0.505 rs77690283 chr14:53233320 C/G cg13660082 chr14:53194042 PSMC6 -0.44 -7.65 -0.38 2e-13 Alzheimer's disease (late onset); LIHC trans rs208520 0.661 rs207111 chr6:66792513 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs2635047 0.600 rs2635056 chr18:44710568 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.93 0.31 7.28e-9 Educational attainment; LIHC trans rs1814175 0.530 rs11040482 chr11:49727068 T/C cg15704280 chr7:45808275 SEPT13 -0.97 -20.66 -0.75 4.12e-62 Height; LIHC cis rs6141600 0.540 rs761312 chr20:34687809 A/G cg03520225 chr20:34742782 EPB41L1 0.47 5.72 0.3 2.28e-8 Height;Hip circumference; LIHC cis rs5771242 0.776 rs6010198 chr22:50610628 A/G cg16473166 chr22:50639996 SELO -0.57 -7.45 -0.37 7.53e-13 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); LIHC cis rs7119 0.717 rs34194537 chr15:77795761 G/A cg17802220 chr15:77601643 NA -0.39 -6.66 -0.34 1.09e-10 Type 2 diabetes; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg06873352 chr17:61820015 STRADA 0.7 11.93 0.54 1.15e-27 Prudent dietary pattern; LIHC cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg02034447 chr16:89574710 SPG7 0.47 7.35 0.37 1.47e-12 Multiple myeloma (IgH translocation); LIHC cis rs15676 0.947 rs3115874 chr9:131579338 G/C cg13708974 chr9:131466143 PKN3 0.38 5.81 0.3 1.43e-8 Blood metabolite levels; LIHC cis rs35146811 1.000 rs35146811 chr7:99720994 A/C cg13334819 chr7:99746414 C7orf59 -0.59 -8.49 -0.42 6.55e-16 Coronary artery disease; LIHC trans rs9929218 0.953 rs3118227 chr16:68734855 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.16 -0.44 4.71e-18 Colorectal cancer; LIHC cis rs1348850 0.789 rs2197611 chr2:178369036 G/C cg27490568 chr2:178487706 NA 0.36 5.72 0.3 2.38e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6120849 0.663 rs13041792 chr20:33545055 G/A cg24642439 chr20:33292090 TP53INP2 0.67 7.82 0.39 6.67e-14 Protein C levels; LIHC cis rs2841277 0.645 rs28380382 chr14:105410827 C/T cg21017887 chr14:105400489 NA 0.66 12.65 0.56 2.44e-30 Rheumatoid arthritis; LIHC cis rs6951245 0.872 rs57068908 chr7:1060084 A/C cg24642844 chr7:1081250 C7orf50 -0.82 -8.3 -0.41 2.47e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs4774899 0.597 rs538382 chr15:56998703 C/A cg26554170 chr1:227968812 SNAP47 0.36 6.04 0.31 4.01e-9 Urinary tract infection frequency; LIHC cis rs8084351 0.577 rs3922754 chr18:50609302 T/C cg24270629 chr18:50823537 DCC 0.46 6.93 0.35 2.16e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs3780486 0.846 rs10758192 chr9:33131651 G/A cg20290983 chr6:43655470 MRPS18A 1.19 31.58 0.86 2.1e-103 IgG glycosylation; LIHC trans rs561341 0.700 rs6505266 chr17:30225813 G/A cg20587970 chr11:113659929 NA -0.51 -6.48 -0.33 3.11e-10 Hip circumference adjusted for BMI; LIHC trans rs1814175 0.817 rs11040474 chr11:49708441 G/A cg15704280 chr7:45808275 SEPT13 -1.04 -23.92 -0.79 5.38e-75 Height; LIHC cis rs7296418 0.922 rs12425009 chr12:123502044 C/T cg00376283 chr12:123451042 ABCB9 0.75 13.59 0.59 6.12e-34 Platelet count; LIHC cis rs9790314 1.000 rs464766 chr3:161087592 C/G cg04691961 chr3:161091175 C3orf57 -0.46 -7.33 -0.37 1.68e-12 Morning vs. evening chronotype; LIHC cis rs11676348 0.805 rs13007219 chr2:218963859 C/A cg00012203 chr2:219082015 ARPC2 -0.52 -7.05 -0.36 1.01e-11 Ulcerative colitis; LIHC cis rs7027203 0.828 rs10122041 chr9:96615517 A/G cg14396892 chr9:96623032 NA -0.32 -6.21 -0.32 1.53e-9 DNA methylation (variation); LIHC cis rs172166 0.637 rs1225595 chr6:28151340 A/T cg23485639 chr6:28045615 ZNF165 0.38 6.04 0.31 4.02e-9 Cardiac Troponin-T levels; LIHC cis rs11792861 0.816 rs28361111 chr9:111761012 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 8.92 0.43 2.8e-17 Menarche (age at onset); LIHC cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg21724239 chr8:58056113 NA 0.59 6.86 0.35 3.17e-11 Developmental language disorder (linguistic errors); LIHC cis rs988712 0.587 rs117567901 chr11:27706040 T/C cg18117895 chr11:27722066 BDNF 0.51 7.16 0.36 4.97e-12 Obesity; LIHC cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC trans rs1814175 0.817 rs11518158 chr11:49985633 G/T cg03929089 chr4:120376271 NA -0.9 -18.69 -0.71 3.18e-54 Height; LIHC cis rs765787 0.530 rs1706835 chr15:45517884 G/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.49 -0.38 6.06e-13 Uric acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24515799 chr6:149867235 PPIL4 -0.44 -6.06 -0.31 3.64e-9 Pancreatic cancer; LIHC cis rs919433 0.963 rs6738836 chr2:198182432 A/G cg03934865 chr2:198174659 NA -0.58 -9.26 -0.45 2.24e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs6066825 0.605 rs761274 chr20:47315362 T/C cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.51e-12 Colorectal cancer; LIHC cis rs56011263 0.687 rs4690186 chr4:703607 G/A cg14024328 chr4:719362 PCGF3 -0.46 -6.73 -0.34 6.98e-11 White blood cell count; LIHC cis rs7945718 0.967 rs4415740 chr11:12783911 C/T cg25843174 chr11:12811716 TEAD1 0.35 7.9 0.39 3.84e-14 Educational attainment (years of education); LIHC cis rs208520 0.690 rs12202401 chr6:66760544 A/G cg07460842 chr6:66804631 NA 0.81 9.21 0.45 3.34e-18 Exhaled nitric oxide output; LIHC cis rs2806561 0.715 rs10753550 chr1:23322471 C/G cg19743168 chr1:23544995 NA -0.37 -6.92 -0.35 2.2e-11 Height; LIHC cis rs3862030 0.503 rs6584506 chr10:104254428 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs10493773 0.502 rs12061951 chr1:86081453 A/G cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.58 -0.38 3.3e-13 Urate levels in overweight individuals; LIHC trans rs1499614 1.000 rs1638731 chr7:66144679 C/T cg05590025 chr7:65112418 INTS4L2 -0.56 -6.09 -0.31 3.04e-9 Gout; LIHC cis rs11227306 0.934 rs11227313 chr11:65588938 C/T cg00576331 chr11:65640516 EFEMP2 -0.41 -5.92 -0.3 8.04e-9 DNA methylation (variation); LIHC cis rs12478296 1.000 rs56292923 chr2:243039986 C/T cg06360820 chr2:242988706 NA -0.83 -11.41 -0.53 9.06e-26 Obesity-related traits; LIHC cis rs11971779 0.941 rs1127424 chr7:139107660 A/G cg07862535 chr7:139043722 LUC7L2 0.69 11.14 0.52 8.27e-25 Diisocyanate-induced asthma; LIHC cis rs875971 0.522 rs709604 chr7:65497434 A/G cg11987759 chr7:65425863 GUSB 0.38 6.07 0.31 3.43e-9 Aortic root size; LIHC cis rs8062405 0.723 rs35175818 chr16:28608746 A/C cg00204512 chr16:28754710 NA 0.42 7.12 0.36 6.45e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs79976124 0.800 rs10944857 chr6:66637078 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.79 0.34 4.91e-11 Type 2 diabetes; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09862616 chr5:122736738 CEP120 0.45 6.51 0.33 2.69e-10 Longevity; LIHC cis rs4727027 0.870 rs1568945 chr7:148874112 T/G cg23583168 chr7:148888333 NA -0.73 -10.33 -0.49 5.82e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs16828019 0.852 rs11209531 chr1:41571021 C/T cg20697417 chr1:41786797 NA 0.31 5.88 0.3 9.66e-9 Intelligence (multi-trait analysis); LIHC cis rs11630290 0.736 rs7183958 chr15:64155534 C/G cg12036633 chr15:63758958 NA -0.65 -5.96 -0.31 6.38e-9 Iris characteristics; LIHC cis rs12638540 0.543 rs13433871 chr3:32559673 A/C cg11605617 chr3:32612461 DYNC1LI1 0.94 8.04 0.4 1.45e-14 Mortality in heart failure; LIHC cis rs2576037 0.901 rs6507719 chr18:44581310 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.49 -7.29 -0.37 2.16e-12 Personality dimensions; LIHC cis rs3741404 0.620 rs11231722 chr11:63967770 C/G cg18225595 chr11:63971243 STIP1 0.63 10.5 0.49 1.57e-22 Platelet count; LIHC trans rs8073060 0.785 rs11659054 chr17:33867678 C/T cg19694781 chr19:47549865 TMEM160 0.63 6.63 0.34 1.32e-10 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs11031096 0.655 rs11031252 chr11:4211165 A/G cg18678763 chr11:4115507 RRM1 -0.42 -6.11 -0.31 2.66e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs2739330 0.828 rs5760102 chr22:24248761 T/C cg06437703 chr8:37914619 EIF4EBP1 -0.49 -7.26 -0.37 2.68e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17270561 0.779 rs17271767 chr6:25886921 C/T cg16482183 chr6:26056742 HIST1H1C 0.64 7.77 0.39 9.54e-14 Iron status biomarkers; LIHC cis rs875971 0.862 rs7786892 chr7:65628876 G/A cg18252515 chr7:66147081 NA 0.42 5.77 0.3 1.79e-8 Aortic root size; LIHC cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg18357526 chr6:26021779 HIST1H4A 1.01 14.83 0.63 9.44e-39 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.534 rs11053020 chr12:34111092 C/G cg26384229 chr12:38710491 ALG10B 0.53 7.2 0.36 3.91e-12 Morning vs. evening chronotype; LIHC cis rs1707322 1.000 rs11211235 chr1:46440375 G/A cg03146154 chr1:46216737 IPP 0.48 7.86 0.39 5.02e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18030105 chr11:3396237 ZNF195 0.43 6.25 0.32 1.23e-9 Pancreatic cancer; LIHC trans rs7618501 1.000 rs11130218 chr3:49752372 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC trans rs17586843 0.528 rs1821010 chr4:116834041 A/G cg25881869 chr10:114609298 LOC143188 0.43 6.57 0.33 1.89e-10 Age-related macular degeneration; LIHC cis rs12079745 0.793 rs12097260 chr1:169317195 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.79 -7.08 -0.36 8.09e-12 QT interval; LIHC cis rs763121 0.889 rs4820335 chr22:38935927 C/G cg14440974 chr22:39074834 NA 0.35 5.9 0.3 8.63e-9 Menopause (age at onset); LIHC cis rs9868809 0.505 rs28793701 chr3:48762683 C/G cg07636037 chr3:49044803 WDR6 -0.81 -7.87 -0.39 4.82e-14 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs7264396 0.635 rs6121073 chr20:34457513 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.74 -0.5 2.21e-23 Total cholesterol levels; LIHC cis rs12079745 0.590 rs12061080 chr1:169332848 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 1.95e-11 QT interval; LIHC cis rs16912285 0.584 rs7131124 chr11:24249455 A/G ch.11.24196551F chr11:24239977 NA 0.79 10.77 0.5 1.71e-23 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs34172651 0.917 rs35283675 chr16:24820393 A/G cg04756594 chr16:24857601 SLC5A11 0.46 7.08 0.36 8.22e-12 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.541 rs2505193 chr10:38394638 G/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs11229555 0.874 rs7102852 chr11:58358348 G/A cg15696309 chr11:58395628 NA -0.74 -8.85 -0.43 4.87e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs11014306 1.000 rs1409306 chr10:25205965 C/G cg17214381 chr4:188916668 ZFP42 -0.55 -6.24 -0.32 1.29e-9 Metabolite levels (Pyroglutamine); LIHC cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.37 -5.71 -0.3 2.44e-8 Obesity-related traits; LIHC cis rs155076 1.000 rs261431 chr13:21865738 A/G cg11317459 chr13:21872234 NA 1.01 11.75 0.54 5.02e-27 White matter hyperintensity burden; LIHC cis rs1801251 0.778 rs778338 chr2:233740227 A/G cg08000102 chr2:233561755 GIGYF2 -0.72 -10.78 -0.5 1.66e-23 Coronary artery disease; LIHC cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg22764044 chr5:178986830 RUFY1 -0.4 -5.88 -0.3 9.73e-9 Lung cancer; LIHC cis rs2637266 0.756 rs846607 chr10:78561254 A/T cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.96e-9 Pulmonary function; LIHC cis rs782590 0.687 rs62165255 chr2:55932585 G/A cg03859395 chr2:55845619 SMEK2 0.8 13.43 0.59 2.56e-33 Metabolic syndrome; LIHC cis rs6952808 0.929 rs4721217 chr7:1973579 C/T cg20295408 chr7:1910781 MAD1L1 -0.46 -6.57 -0.33 1.9e-10 Bipolar disorder and schizophrenia; LIHC cis rs2204008 0.777 rs6582664 chr12:37947022 A/G cg26384229 chr12:38710491 ALG10B -0.47 -6.62 -0.34 1.36e-10 Bladder cancer; LIHC cis rs7223966 1.000 rs7222060 chr17:61868279 C/T cg05941027 chr17:61774174 LIMD2 0.35 7.35 0.37 1.48e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 11.5 0.53 4.16e-26 Height; LIHC cis rs611744 0.647 rs1379336 chr8:109276606 G/T cg18478394 chr8:109455254 TTC35 0.42 7.21 0.36 3.61e-12 Dupuytren's disease; LIHC cis rs61712019 0.563 rs35286009 chr2:77730722 C/G cg11252801 chr2:77748917 LRRTM4 0.45 6.17 0.32 1.98e-9 Schizophrenia; LIHC cis rs10927875 0.688 rs2009371 chr1:16348083 A/T cg21385522 chr1:16154831 NA 0.72 9.38 0.45 9.41e-19 Dilated cardiomyopathy; LIHC cis rs249954 0.512 rs703769 chr16:23654509 T/G cg09867953 chr16:23706666 ERN2 0.38 6.39 0.33 5.36e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6952808 0.595 rs3800916 chr7:2166072 C/T cg04267008 chr7:1944627 MAD1L1 -0.51 -7.97 -0.4 2.44e-14 Bipolar disorder and schizophrenia; LIHC trans rs10506458 0.834 rs55966529 chr12:63384114 A/C cg22491629 chr6:157744540 C6orf35 -0.6 -10.79 -0.5 1.42e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs611744 0.837 rs438191 chr8:109124222 A/G cg21045802 chr8:109455806 TTC35 0.5 8.48 0.42 7e-16 Dupuytren's disease; LIHC cis rs694739 0.628 rs617051 chr11:64133638 C/A cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.02e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs4713118 0.527 rs4713151 chr6:28136356 G/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Parkinson's disease; LIHC cis rs807029 0.577 rs7902510 chr10:102757934 C/T cg27255678 chr10:102756921 LZTS2 0.52 7.29 0.37 2.22e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -11.07 -0.51 1.5e-24 Platelet count; LIHC cis rs807029 0.533 rs2295716 chr10:102744214 T/C cg17130504 chr10:102756923 LZTS2 0.56 7.8 0.39 7.35e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1348850 0.914 rs4893944 chr2:178289357 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.84 13.32 0.58 6.55e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2153535 0.541 rs1414352 chr6:8485547 A/C cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs9381040 0.610 rs717883 chr6:41045270 T/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.22 -0.32 1.44e-9 Alzheimer's disease (late onset); LIHC cis rs244293 0.831 rs11079149 chr17:53095046 A/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.51 0.38 5.12e-13 Menarche (age at onset); LIHC cis rs929354 0.772 rs3802120 chr7:156977794 C/T cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 22.8 0.78 1.28e-70 Prudent dietary pattern; LIHC cis rs7520050 0.933 rs6666743 chr1:46311275 C/T cg03146154 chr1:46216737 IPP -0.37 -5.92 -0.3 8e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7508 0.509 rs441764 chr8:17903157 A/G cg01800426 chr8:17659068 MTUS1 -0.41 -6.66 -0.34 1.08e-10 Atrial fibrillation; LIHC cis rs929354 0.713 rs6946947 chr7:156948787 T/C cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs7312933 0.558 rs11181463 chr12:42763636 C/T cg01256987 chr12:42539512 GXYLT1 -0.38 -6.3 -0.32 9.16e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs12908161 1.000 rs35960805 chr15:85343980 T/G cg12863693 chr15:85201151 NMB 0.44 6.34 0.32 7.18e-10 Schizophrenia; LIHC cis rs3008870 0.755 rs1024230 chr1:67512920 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.51 8.89 0.43 3.61e-17 Lymphocyte percentage of white cells; LIHC trans rs875971 0.660 rs62465434 chr7:66005152 A/C cg26939375 chr7:64535504 NA 0.43 6.96 0.35 1.72e-11 Aortic root size; LIHC cis rs35740288 0.539 rs34362339 chr15:86337628 C/T cg20737812 chr15:86336631 KLHL25 -0.42 -5.83 -0.3 1.27e-8 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs875971 0.825 rs1000464 chr7:65777909 G/C cg18252515 chr7:66147081 NA 0.44 6.28 0.32 1.06e-9 Aortic root size; LIHC cis rs1707322 0.685 rs56177313 chr1:46225806 A/C cg06784218 chr1:46089804 CCDC17 0.42 7.63 0.38 2.34e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6977660 0.598 rs10239147 chr7:19787459 T/C cg07541023 chr7:19748670 TWISTNB 0.49 7.32 0.37 1.74e-12 Thyroid stimulating hormone; LIHC cis rs896854 0.517 rs2013597 chr8:95951807 G/A cg09323728 chr8:95962352 TP53INP1 -0.28 -5.74 -0.3 2.06e-8 Type 2 diabetes; LIHC cis rs4906332 0.966 rs35799018 chr14:103893475 G/A cg04998671 chr14:104000505 TRMT61A -0.45 -6.26 -0.32 1.12e-9 Coronary artery disease; LIHC cis rs9372253 0.678 rs6568644 chr6:110707820 C/T cg00083206 chr6:110721305 DDO -0.33 -6.6 -0.34 1.57e-10 Platelet distribution width; LIHC cis rs7552404 0.696 rs1417405 chr1:76457797 T/C cg10523679 chr1:76189770 ACADM 0.61 7.16 0.36 4.89e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1005277 0.579 rs1780115 chr10:38524773 C/T cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs8180040 0.726 rs2305634 chr3:47043538 A/G cg27129171 chr3:47204927 SETD2 -0.66 -11.56 -0.53 2.55e-26 Colorectal cancer; LIHC cis rs7107174 1.000 rs10899479 chr11:78052539 A/G cg02023728 chr11:77925099 USP35 0.47 8.98 0.44 1.88e-17 Testicular germ cell tumor; LIHC cis rs4975709 0.589 rs4975745 chr5:1861058 G/C cg14773178 chr5:1868261 NA 0.26 6.98 0.35 1.56e-11 Cardiovascular disease risk factors; LIHC cis rs611744 0.901 rs639746 chr8:109234825 T/C cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg12463550 chr7:65579703 CRCP 0.67 7.02 0.35 1.23e-11 Diabetic kidney disease; LIHC cis rs6429082 0.608 rs4659836 chr1:235564412 G/A cg26050004 chr1:235667680 B3GALNT2 -0.46 -6.85 -0.35 3.46e-11 Adiposity; LIHC cis rs9368481 0.672 rs3931463 chr6:26939797 G/A cg12292205 chr6:26970375 C6orf41 0.47 7.9 0.39 3.73e-14 Autism spectrum disorder or schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16582978 chr5:170814878 NPM1 0.42 6.03 0.31 4.16e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1538970 0.739 rs4660863 chr1:45955868 T/C cg05343316 chr1:45956843 TESK2 0.63 9.45 0.46 5.47e-19 Platelet count; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs875971 0.545 rs66594357 chr7:65792784 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.48 0.38 6.27e-13 Aortic root size; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00480142 chr12:96046743 NA 0.43 6.53 0.33 2.39e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs412000 0.560 rs4793583 chr17:56451407 A/C cg12560992 chr17:57184187 TRIM37 -0.8 -12.43 -0.56 1.56e-29 Primary tooth development (time to first tooth eruption); LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg13409248 chr3:40428643 ENTPD3 -0.48 -8.37 -0.41 1.52e-15 Renal cell carcinoma; LIHC cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg07424592 chr7:64974309 NA -0.82 -9.43 -0.45 6.33e-19 Diabetic kidney disease; LIHC cis rs9911578 0.935 rs7216698 chr17:57007495 G/A cg05425664 chr17:57184151 TRIM37 -0.55 -8.3 -0.41 2.4e-15 Intelligence (multi-trait analysis); LIHC cis rs5770917 1.000 rs762677 chr22:51017713 G/A cg08260245 chr22:51016501 CPT1B;CHKB-CPT1B -0.4 -5.81 -0.3 1.44e-8 Narcolepsy; LIHC cis rs425277 0.583 rs925905 chr1:2044037 T/C cg04315214 chr1:2043799 PRKCZ 0.46 7.35 0.37 1.5e-12 Height; LIHC cis rs2204008 0.603 rs4397954 chr12:38089157 T/C cg26384229 chr12:38710491 ALG10B 0.81 9.5 0.46 3.89e-19 Bladder cancer; LIHC cis rs7412746 0.658 rs72704685 chr1:150897687 C/G cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg21724239 chr8:58056113 NA 0.49 6.36 0.33 6.38e-10 Developmental language disorder (linguistic errors); LIHC cis rs2840044 1.000 rs9891800 chr17:33895015 G/C cg20932281 chr17:33905541 PEX12 0.42 5.81 0.3 1.44e-8 Response to radiotherapy in cancer (late toxicity); LIHC cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg04944784 chr2:26401820 FAM59B 0.72 9.19 0.45 3.85e-18 Gut microbiome composition (summer); LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg05277466 chr16:88082055 BANP 0.47 6.38 0.33 5.81e-10 Myopia (pathological); LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.95 -21.07 -0.75 9.58e-64 Prudent dietary pattern; LIHC cis rs7777484 0.500 rs757787 chr7:2836355 G/A cg18446336 chr7:2847575 GNA12 -0.33 -6.47 -0.33 3.38e-10 Height; LIHC cis rs17685 0.753 rs6951943 chr7:75772452 A/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs62458065 0.568 rs62466415 chr7:32518254 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.71 -7.1 -0.36 7.45e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs231513 0.954 rs231505 chr17:41970268 A/T cg26893861 chr17:41843967 DUSP3 0.62 5.81 0.3 1.47e-8 Cognitive function; LIHC cis rs2243480 0.708 rs13242216 chr7:65898277 T/C cg18252515 chr7:66147081 NA -1.3 -16.7 -0.67 3.38e-46 Diabetic kidney disease; LIHC cis rs600806 0.821 rs4970840 chr1:109873367 A/G cg23091122 chr1:110024289 SYPL2 -0.45 -5.93 -0.31 7.4e-9 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg00612595 chr21:47717864 NA -0.35 -5.76 -0.3 1.9e-8 Testicular germ cell tumor; LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg18279126 chr7:2041391 MAD1L1 0.39 6.51 0.33 2.74e-10 Bipolar disorder and schizophrenia; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg05185784 chr16:90016020 DEF8 -0.48 -6.39 -0.33 5.56e-10 Skin colour saturation; LIHC cis rs473651 0.904 rs501333 chr2:239336045 G/A cg18131467 chr2:239335373 ASB1 1.09 20.8 0.75 1.08e-62 Multiple system atrophy; LIHC cis rs4819052 0.679 rs2838859 chr21:46684517 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.64 10.03 0.48 6.29e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg26338869 chr17:61819248 STRADA 0.61 8.94 0.44 2.57e-17 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs2739509 chr1:231526765 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.28 0.45 2.01e-18 Hemoglobin concentration; LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg26338869 chr17:61819248 STRADA 0.6 8.75 0.43 9.91e-17 Prudent dietary pattern; LIHC cis rs9858542 0.953 rs9827708 chr3:49649989 C/G cg03060546 chr3:49711283 APEH -0.58 -7.8 -0.39 7.55e-14 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs7613875 0.620 rs7624030 chr3:50071279 A/C cg21659725 chr3:3221576 CRBN -0.55 -8.18 -0.4 5.58e-15 Body mass index; LIHC cis rs600806 0.745 rs4246517 chr1:110007636 G/C cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.49 -0.33 3.08e-10 Intelligence (multi-trait analysis); LIHC trans rs801193 1.000 rs2659915 chr7:66153101 A/G cg26939375 chr7:64535504 NA 0.41 6.62 0.34 1.42e-10 Aortic root size; LIHC cis rs10089 0.953 rs10223203 chr5:127527646 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.52 -6.41 -0.33 4.93e-10 Ileal carcinoids; LIHC cis rs4819052 0.704 rs2297283 chr21:46683590 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.6 8.91 0.43 2.98e-17 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5769765 0.779 rs12170530 chr22:50318422 T/G cg09182678 chr22:50328711 NA -0.39 -5.82 -0.3 1.36e-8 Schizophrenia; LIHC cis rs473651 0.692 rs579511 chr2:239334914 C/G cg21699342 chr2:239360505 ASB1 0.34 6.48 0.33 3.21e-10 Multiple system atrophy; LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg05896524 chr21:47604654 C21orf56 0.51 8.25 0.41 3.55e-15 Testicular germ cell tumor; LIHC cis rs904251 0.797 rs1757181 chr6:37485728 A/G cg01843034 chr6:37503916 NA 0.51 8.22 0.41 4.13e-15 Cognitive performance; LIHC cis rs1801251 1.000 rs2592105 chr2:233645968 C/G cg08000102 chr2:233561755 GIGYF2 0.79 11.76 0.54 4.78e-27 Coronary artery disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12232852 chr3:69129018 UBA3 0.47 7.21 0.36 3.67e-12 Cognitive function; LIHC cis rs1559088 0.847 rs8110181 chr19:33605939 G/A cg17764715 chr19:33622953 WDR88 0.45 6.5 0.33 2.78e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs60871478 0.592 rs4275123 chr7:857352 A/G cg04727924 chr7:799746 HEATR2 0.53 6.79 0.34 5.09e-11 Cerebrospinal P-tau181p levels; LIHC cis rs6782228 0.606 rs1127030 chr3:128338953 T/C cg16766828 chr3:128327626 NA -0.41 -6.46 -0.33 3.69e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs826838 1.000 rs9795768 chr12:39012479 T/C cg13010199 chr12:38710504 ALG10B 0.56 6.91 0.35 2.38e-11 Heart rate; LIHC cis rs751728 1.000 rs4342423 chr6:33732679 C/T cg25922239 chr6:33757077 LEMD2 0.46 7.61 0.38 2.62e-13 Crohn's disease; LIHC cis rs1559088 0.847 rs2287680 chr19:33608566 A/G cg27124370 chr19:33622961 WDR88 -0.54 -8.56 -0.42 3.78e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6815814 0.851 rs9715769 chr4:38774489 A/C cg06935464 chr4:38784597 TLR10 0.49 7.56 0.38 3.65e-13 Breast cancer; LIHC cis rs6120849 0.707 rs6088690 chr20:33633326 A/G cg24642439 chr20:33292090 TP53INP2 0.65 7.05 0.36 9.65e-12 Protein C levels; LIHC cis rs860295 0.580 rs6672284 chr1:155277963 C/T cg02153340 chr1:155202674 NA -0.37 -6.58 -0.34 1.73e-10 Body mass index; LIHC cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg15857475 chr8:145742913 RECQL4;LRRC14 -0.54 -8.0 -0.4 1.91e-14 Age at first birth; LIHC cis rs12365397 0.748 rs11037372 chr11:43254162 C/A cg16667275 chr11:43333495 API5 0.42 6.31 0.32 8.67e-10 Migraine; LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg09455208 chr3:40491958 NA 0.39 7.94 0.39 2.93e-14 Renal cell carcinoma; LIHC cis rs6840360 0.593 rs2175409 chr4:152701656 A/G cg22705602 chr4:152727874 NA -0.41 -8.66 -0.42 1.95e-16 Intelligence (multi-trait analysis); LIHC cis rs4853012 0.838 rs60964317 chr2:74343423 A/T cg01017244 chr2:74357527 NA 0.63 11.27 0.52 2.99e-25 Gestational age at birth (maternal effect); LIHC cis rs2455799 0.634 rs1584326 chr3:15903951 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.51 -0.38 5.11e-13 Mean platelet volume; LIHC cis rs7258465 0.965 rs2561043 chr19:18622683 A/T cg10790698 chr19:18539756 SSBP4 -0.35 -7.41 -0.37 9.66e-13 Breast cancer; LIHC cis rs9611565 0.573 rs9306355 chr22:42111896 A/T cg03806693 chr22:41940476 POLR3H 0.8 9.01 0.44 1.46e-17 Vitiligo; LIHC cis rs7662987 0.517 rs2602865 chr4:100034841 T/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs11586313 0.507 rs3856026 chr1:152869763 T/C cg07796016 chr1:152779584 LCE1C -0.36 -5.83 -0.3 1.26e-8 Vitamin D levels; LIHC cis rs7481584 0.717 rs3759025 chr11:3017377 G/A cg25174290 chr11:3078921 CARS -0.4 -5.88 -0.3 9.68e-9 Calcium levels; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg00800038 chr16:89945340 TCF25 -0.69 -10.96 -0.51 3.73e-24 Skin colour saturation; LIHC cis rs12291225 0.546 rs12291662 chr11:14342949 T/C cg19336497 chr11:14380999 RRAS2 -0.67 -14.14 -0.61 4.54e-36 Sense of smell; LIHC cis rs769267 0.965 rs7254230 chr19:19434350 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.62 -10.08 -0.48 4.34e-21 Tonsillectomy; LIHC cis rs919433 0.680 rs11680291 chr2:198409884 A/G cg10820045 chr2:198174542 NA 0.5 7.98 0.4 2.18e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.24 0.45 2.6e-18 Bipolar disorder; LIHC cis rs10089 0.953 rs2190797 chr5:127352875 C/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.52 6.24 0.32 1.33e-9 Ileal carcinoids; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.6 0.56 3.7e-30 Prudent dietary pattern; LIHC cis rs1005277 0.522 rs1208767 chr10:38042295 G/T cg25427524 chr10:38739819 LOC399744 -0.63 -12.08 -0.55 3.25e-28 Extrinsic epigenetic age acceleration; LIHC cis rs7961581 0.719 rs1798071 chr12:71599401 C/A cg05756094 chr12:71608604 NA 0.41 6.71 0.34 7.99e-11 Type 2 diabetes; LIHC cis rs2933343 0.729 rs789224 chr3:128598231 A/C cg25356066 chr3:128598488 ACAD9 0.55 7.66 0.38 1.9e-13 IgG glycosylation; LIHC cis rs7615952 0.599 rs1044215 chr3:125725559 C/G cg05084668 chr3:125655381 ALG1L -0.43 -7.14 -0.36 5.47e-12 Blood pressure (smoking interaction); LIHC cis rs6500602 0.561 rs62039231 chr16:4519548 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 6.09 0.31 2.99e-9 Schizophrenia; LIHC cis rs79839061 0.610 rs11726280 chr4:864077 C/T cg07828340 chr4:882639 GAK 0.82 6.76 0.34 5.85e-11 Intelligence (multi-trait analysis); LIHC cis rs7607369 0.759 rs10179708 chr2:219390967 T/A cg02985541 chr2:219472218 PLCD4 -0.42 -6.86 -0.35 3.33e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg21782813 chr7:2030301 MAD1L1 0.41 6.91 0.35 2.44e-11 Bipolar disorder and schizophrenia; LIHC cis rs3760982 0.565 rs3786956 chr19:44286829 C/T cg11993925 chr19:44307056 LYPD5 0.31 6.89 0.35 2.63e-11 Breast cancer (estrogen-receptor negative);Breast cancer; LIHC cis rs2073300 0.609 rs6137936 chr20:23385232 C/T cg12062639 chr20:23401060 NAPB 1.08 14.26 0.61 1.61e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9640161 0.789 rs28432021 chr7:150046235 G/C cg10018233 chr7:150070692 REPIN1 0.52 8.34 0.41 1.89e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs7100689 0.646 rs4601708 chr10:82119583 G/T cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg07157834 chr1:205819609 PM20D1 0.68 10.3 0.49 7.28e-22 Menarche (age at onset); LIHC cis rs6750795 0.569 rs1667313 chr2:232408018 A/C cg19187155 chr2:232395269 NMUR1 0.58 9.15 0.44 5.35e-18 Height; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12609600 chr11:1595974 HCCA2;LOC338651 0.38 6.98 0.35 1.54e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs9326248 0.603 rs7396061 chr11:116750874 A/C cg01368799 chr11:117014884 PAFAH1B2 0.59 8.67 0.42 1.81e-16 Blood protein levels; LIHC cis rs11718455 0.585 rs11710802 chr3:43930155 T/G cg08738300 chr3:44038990 NA 0.36 6.11 0.31 2.65e-9 Coronary artery disease; LIHC cis rs11676348 0.935 rs6716276 chr2:218962205 A/G cg00012203 chr2:219082015 ARPC2 -0.52 -7.02 -0.35 1.19e-11 Ulcerative colitis; LIHC cis rs7546 0.504 rs2015319 chr16:4936280 C/G cg08329684 chr16:4932620 PPL -0.43 -7.6 -0.38 2.92e-13 Cancer; LIHC cis rs1568889 1.000 rs12791341 chr11:28335452 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.91 0.35 2.36e-11 Bipolar disorder; LIHC cis rs7116495 0.609 rs7113520 chr11:71691946 G/A cg10381502 chr11:71823885 C11orf51 -1.0 -8.24 -0.41 3.84e-15 Severe influenza A (H1N1) infection; LIHC cis rs4746818 1.000 rs1506770 chr10:70964357 G/A cg11621586 chr10:70884670 VPS26A 0.84 13.52 0.59 1.11e-33 Left atrial antero-posterior diameter; LIHC cis rs4808199 0.847 rs34647936 chr19:19548239 T/G cg03709012 chr19:19516395 GATAD2A 1.08 19.18 0.72 3.56e-56 Nonalcoholic fatty liver disease; LIHC cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.07 -0.31 3.48e-9 Colorectal cancer; LIHC cis rs875971 0.825 rs1129531 chr7:65619104 C/T cg18876405 chr7:65276391 NA -0.35 -6.12 -0.31 2.63e-9 Aortic root size; LIHC cis rs2153535 0.541 rs4637688 chr6:8446501 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.99 0.4 2.09e-14 Motion sickness; LIHC cis rs6088590 0.561 rs6059926 chr20:33164804 C/T cg08999081 chr20:33150536 PIGU 0.69 13.69 0.59 2.57e-34 Coronary artery disease; LIHC trans rs208520 0.526 rs2881644 chr6:66803535 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.03 20.12 0.74 5.76e-60 Exhaled nitric oxide output; LIHC cis rs10791097 0.642 rs7107568 chr11:130779668 T/C cg22079354 chr11:130786696 SNX19 0.48 7.23 0.36 3.15e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6951245 0.810 rs117800627 chr7:1081075 G/C cg24642844 chr7:1081250 C7orf50 -0.89 -9.02 -0.44 1.35e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.13 -0.61 5.04e-36 Alzheimer's disease; LIHC cis rs9902453 1.000 rs7221743 chr17:28407876 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.59 -0.53 1.95e-26 Coffee consumption (cups per day); LIHC cis rs72627123 0.867 rs74395411 chr14:74478584 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.75 0.47 5.75e-20 Morning vs. evening chronotype; LIHC cis rs4824093 0.610 rs58888255 chr22:50315627 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.74 -5.74 -0.3 2.13e-8 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg19318889 chr4:1322082 MAEA -0.46 -6.41 -0.33 4.7e-10 Obesity-related traits; LIHC cis rs56011263 0.687 rs4690188 chr4:703930 G/C cg14024328 chr4:719362 PCGF3 -0.48 -7.14 -0.36 5.61e-12 White blood cell count; LIHC cis rs3806843 0.735 rs2530235 chr5:140072647 G/T cg16179182 chr5:140090404 VTRNA1-1 0.36 5.95 0.31 6.72e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg02881034 chr2:86426836 MRPL35 0.34 6.41 0.33 4.76e-10 Calcium levels; LIHC cis rs2842992 0.872 rs1570318 chr6:160111473 C/T cg11366901 chr6:160182831 ACAT2 0.93 15.25 0.64 2.01e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs7904368 0.901 rs7923189 chr10:16850214 C/T cg14835575 chr10:16859367 RSU1 0.58 8.22 0.41 4.39e-15 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs10769945 0.679 rs2137322 chr11:1917354 A/G cg23202291 chr11:1979235 NA -0.42 -6.05 -0.31 3.91e-9 DNA methylation (variation); LIHC cis rs7909074 0.531 rs879344 chr10:45400667 G/C cg04218760 chr10:45406644 TMEM72 -0.19 -5.76 -0.3 1.88e-8 Mean corpuscular volume; LIHC cis rs3853824 0.930 rs11079260 chr17:54908599 G/T cg13675837 chr17:54910204 DGKE 0.42 5.91 0.3 8.42e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs875971 0.545 rs1796222 chr7:66057154 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.33 -6.56 -0.33 2.05e-10 Aortic root size; LIHC trans rs783540 0.746 rs7165125 chr15:83297936 C/G cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.13 -0.31 2.37e-9 Schizophrenia; LIHC cis rs5769765 0.819 rs9616379 chr22:50312035 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs2153535 0.580 rs718503 chr6:8527463 A/T cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.15e-16 Motion sickness; LIHC cis rs8053891 0.756 rs28629271 chr16:72003732 C/T cg01557791 chr16:72042693 DHODH -0.47 -6.7 -0.34 8.73e-11 Coronary artery disease; LIHC cis rs2380220 0.541 rs72928273 chr6:96079360 C/T cg15832292 chr6:96025679 MANEA -0.72 -9.0 -0.44 1.64e-17 Behavioural disinhibition (generation interaction); LIHC cis rs1322512 1.000 rs2758816 chr6:152968338 A/T cg03415253 chr6:152958462 SYNE1 -0.33 -5.97 -0.31 6.06e-9 Tonometry; LIHC cis rs9916302 0.904 rs602282 chr17:37433021 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.42 -0.59 2.81e-33 Glomerular filtration rate (creatinine); LIHC cis rs1059312 0.500 rs10734964 chr12:129286486 C/T cg09035930 chr12:129282057 SLC15A4 0.51 7.86 0.39 5.11e-14 Systemic lupus erythematosus; LIHC cis rs9916302 0.861 rs2338801 chr17:37490780 G/T cg00129232 chr17:37814104 STARD3 0.37 5.9 0.3 8.52e-9 Glomerular filtration rate (creatinine); LIHC cis rs9790314 0.936 rs7629987 chr3:161002023 A/C cg04691961 chr3:161091175 C3orf57 -0.38 -5.97 -0.31 5.97e-9 Morning vs. evening chronotype; LIHC cis rs1336900 0.641 rs6587756 chr1:150546865 A/T cg15448220 chr1:150897856 SETDB1 -0.43 -6.35 -0.32 6.71e-10 Blood protein levels; LIHC cis rs1801251 1.000 rs4973053 chr2:233670099 G/A cg25237894 chr2:233734115 C2orf82 -0.59 -11.54 -0.53 3.12e-26 Coronary artery disease; LIHC cis rs6964587 1.000 rs10281556 chr7:91660053 C/T cg17063962 chr7:91808500 NA -1.01 -19.62 -0.73 5.91e-58 Breast cancer; LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg09455208 chr3:40491958 NA 0.39 7.92 0.39 3.48e-14 Renal cell carcinoma; LIHC trans rs2243480 1.000 rs313832 chr7:65550891 G/T cg10756647 chr7:56101905 PSPH 1.06 12.81 0.57 5.83e-31 Diabetic kidney disease; LIHC cis rs748404 0.650 rs556851 chr15:43571219 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.7 0.34 8.66e-11 Lung cancer; LIHC cis rs2762353 0.603 rs10946798 chr6:25781853 T/G cg03517284 chr6:25882590 NA 0.48 6.41 0.33 4.85e-10 Blood metabolite levels; LIHC cis rs34779708 0.736 rs34195979 chr10:35549817 T/C cg03585969 chr10:35415529 CREM 0.74 10.66 0.5 4.27e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg07424592 chr7:64974309 NA 0.84 9.54 0.46 2.71e-19 Diabetic kidney disease; LIHC cis rs9783347 1.000 rs4150622 chr11:18365710 A/G cg15585147 chr11:18324498 HPS5 0.43 6.64 0.34 1.21e-10 Pancreatic cancer; LIHC cis rs892961 0.932 rs11658267 chr17:75411884 C/T cg01320579 chr17:75405842 SEPT9 -0.5 -7.15 -0.36 5.44e-12 Airflow obstruction; LIHC trans rs6598955 0.671 rs17257176 chr1:26578233 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC cis rs6977660 0.714 rs4721827 chr7:19825655 A/G cg07541023 chr7:19748670 TWISTNB 0.42 6.13 0.31 2.42e-9 Thyroid stimulating hormone; LIHC cis rs908922 0.676 rs11205014 chr1:152483634 C/T cg23254163 chr1:152506842 NA 0.23 5.94 0.31 6.86e-9 Hair morphology; LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg26338869 chr17:61819248 STRADA 0.59 8.72 0.43 1.19e-16 Prudent dietary pattern; LIHC cis rs7772486 0.817 rs2144477 chr6:146406248 C/T cg13319975 chr6:146136371 FBXO30 -0.38 -6.23 -0.32 1.37e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg08888203 chr3:10149979 C3orf24 0.56 6.43 0.33 4.31e-10 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12427896 chr2:111880694 BCL2L11 0.39 6.55 0.33 2.17e-10 Cognitive function; LIHC trans rs1484948 0.560 rs4261271 chr11:41943080 C/T cg09339301 chr6:163836245 QKI 0.56 6.09 0.31 3.06e-9 RR interval (heart rate); LIHC cis rs9296092 0.538 rs56199698 chr6:33534505 G/C cg13560919 chr6:33536144 NA -0.4 -6.57 -0.33 1.92e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05742294 chr8:124169368 NA 0.46 6.61 0.34 1.43e-10 Cognitive function; LIHC cis rs8180040 0.903 rs11710013 chr3:47296921 T/C cg27129171 chr3:47204927 SETD2 0.67 11.55 0.53 2.84e-26 Colorectal cancer; LIHC cis rs909002 0.830 rs1356803 chr1:32131163 C/G cg13919466 chr1:32135498 COL16A1 -0.34 -6.31 -0.32 8.71e-10 Intelligence (multi-trait analysis); LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg03031660 chr17:73257791 MRPS7;GGA3 -0.41 -6.38 -0.33 5.71e-10 Body mass index; LIHC cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg12310025 chr6:25882481 NA -0.65 -9.32 -0.45 1.47e-18 Blood metabolite levels; LIHC cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg12311346 chr5:56204834 C5orf35 0.55 7.26 0.37 2.67e-12 Initial pursuit acceleration; LIHC cis rs921968 0.565 rs6436082 chr2:219639430 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs12079745 0.623 rs2901092 chr1:169456393 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.71 -7.3 -0.37 2.08e-12 QT interval; LIHC cis rs11577318 0.853 rs2276712 chr1:26627478 T/C cg00852783 chr1:26633632 UBXN11 0.42 6.8 0.35 4.66e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs2073499 0.935 rs74398439 chr3:50331927 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 0.62 6.92 0.35 2.26e-11 Schizophrenia; LIHC trans rs4824093 0.610 rs4141437 chr22:50243719 C/G cg09872104 chr7:134855509 C7orf49 0.75 6.25 0.32 1.2e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs708547 0.647 rs6843644 chr4:57891239 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.47 6.85 0.35 3.35e-11 Response to bleomycin (chromatid breaks); LIHC cis rs3768617 0.811 rs4285667 chr1:182970225 T/A ch.1.3577855R chr1:183094577 LAMC1 0.49 7.74 0.39 1.12e-13 Fuchs's corneal dystrophy; LIHC cis rs9858542 0.953 rs11926781 chr3:49603289 C/T cg03060546 chr3:49711283 APEH -0.52 -6.98 -0.35 1.52e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 11.55 0.53 2.78e-26 Platelet count; LIHC cis rs2404602 1.000 rs2404740 chr15:76852143 C/T cg03037974 chr15:76606532 NA 0.77 15.22 0.64 2.7e-40 Blood metabolite levels; LIHC cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg18357526 chr6:26021779 HIST1H4A 1.06 15.95 0.65 3.23e-43 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.520 rs2516835 chr2:99779131 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs2859741 0.967 rs535876 chr1:37484052 C/G cg09363841 chr1:37513479 NA -0.19 -6.01 -0.31 4.65e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs3806843 0.735 rs778597 chr5:140040665 A/G cg16179182 chr5:140090404 VTRNA1-1 -0.36 -5.95 -0.31 6.72e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7100689 0.646 rs10400045 chr10:82077032 A/G cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs7613875 0.537 rs6446195 chr3:50070853 A/G cg21467203 chr3:49911342 NA 0.52 9.46 0.46 5.1e-19 Body mass index; LIHC cis rs2250402 0.510 rs2291621 chr15:40324837 C/T cg01081584 chr15:40268610 EIF2AK4 -0.53 -6.18 -0.32 1.87e-9 Corneal curvature; LIHC cis rs2075371 0.933 rs1868785 chr7:133945855 G/C cg20476274 chr7:133979776 SLC35B4 0.7 11.65 0.53 1.25e-26 Mean platelet volume; LIHC cis rs11229555 0.645 rs61889554 chr11:58424081 C/A cg15696309 chr11:58395628 NA -0.64 -6.21 -0.32 1.56e-9 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1055129 0.560 rs2608880 chr17:73938957 C/T cg19302996 chr17:73780495 UNK -0.47 -6.69 -0.34 9.14e-11 White matter hyperintensity burden; LIHC cis rs1443512 0.812 rs1867299 chr12:54329975 T/C cg17410650 chr12:54324560 NA -0.4 -7.22 -0.36 3.4e-12 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs1451375 0.652 rs10249420 chr7:50623451 C/G cg14593290 chr7:50529359 DDC -0.48 -7.85 -0.39 5.28e-14 Malaria; LIHC cis rs4319547 0.656 rs10744209 chr12:122931568 G/A cg23029597 chr12:123009494 RSRC2 -0.53 -7.4 -0.37 1.04e-12 Body mass index; LIHC cis rs4908768 0.501 rs6577488 chr1:8534529 T/C cg20416874 chr1:8611966 RERE -0.69 -14.74 -0.62 2.15e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs9486719 0.947 rs11153071 chr6:97039741 G/A cg06623918 chr6:96969491 KIAA0776 -0.68 -6.85 -0.35 3.49e-11 Migraine;Coronary artery disease; LIHC cis rs7520050 0.807 rs3013595 chr1:46153203 G/A cg24296786 chr1:45957014 TESK2 -0.4 -5.88 -0.3 9.95e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7953249 0.594 rs11065384 chr12:121423285 T/C cg02403541 chr12:121454288 C12orf43 -0.43 -7.09 -0.36 7.56e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs74544699 1.000 rs4082827 chr4:74831180 A/C cg15398841 chr4:74847761 PF4 -0.56 -5.85 -0.3 1.12e-8 Growth-regulated protein alpha levels; LIHC cis rs1559088 0.739 rs9304845 chr19:33592794 A/G cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9660992 0.686 rs1668870 chr1:205239031 C/G cg21545522 chr1:205238299 TMCC2 0.42 8.03 0.4 1.54e-14 Mean corpuscular volume;Mean platelet volume; LIHC cis rs9768139 0.708 rs921615 chr7:158117935 A/G cg06219351 chr7:158114137 PTPRN2 -0.21 -6.04 -0.31 3.96e-9 Calcium levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13445258 chr3:128369860 RPN1 0.4 6.52 0.33 2.57e-10 Cognitive function; LIHC cis rs763121 0.524 rs760645 chr22:39032270 C/T cg06022373 chr22:39101656 GTPBP1 0.55 9.58 0.46 2.01e-19 Menopause (age at onset); LIHC cis rs6754311 0.731 rs2164210 chr2:136580287 T/C cg07169764 chr2:136633963 MCM6 -0.67 -9.97 -0.47 9.98e-21 Mosquito bite size; LIHC cis rs7223966 1.000 rs55674647 chr17:61794195 T/C cg05941027 chr17:61774174 LIMD2 0.37 7.44 0.37 8.41e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs116095464 0.510 rs10057501 chr5:239545 T/C cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.8e-52 Breast cancer; LIHC cis rs1042058 0.565 rs2480297 chr10:30754512 A/G cg25182066 chr10:30743637 MAP3K8 -0.69 -10.97 -0.51 3.38e-24 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC trans rs916888 0.779 rs430685 chr17:44859148 T/C cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2439831 0.681 rs28653441 chr15:43677262 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.86 15.58 0.64 9.78e-42 Lung cancer in ever smokers; LIHC cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg06466757 chr4:1255808 NA 0.34 5.82 0.3 1.32e-8 Obesity-related traits; LIHC cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg02931644 chr1:25747376 RHCE 0.35 7.74 0.39 1.15e-13 Erythrocyte sedimentation rate; LIHC cis rs12701220 0.504 rs12702092 chr7:1145868 G/A cg04025307 chr7:1156635 C7orf50 0.47 5.86 0.3 1.12e-8 Bronchopulmonary dysplasia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23211358 chr19:17378293 C19orf62 -0.52 -6.23 -0.32 1.35e-9 Systolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04691540 chr1:179198414 ABL2 0.42 6.97 0.35 1.65e-11 Pancreatic cancer; LIHC cis rs941873 0.805 rs10824747 chr10:81118464 T/C cg09469691 chr10:81107165 PPIF 0.68 10.24 0.48 1.19e-21 Height; LIHC cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg00750074 chr16:89608354 SPG7 -0.49 -7.92 -0.39 3.27e-14 Multiple myeloma (IgH translocation); LIHC cis rs875971 0.862 rs6971059 chr7:66067032 A/G cg18876405 chr7:65276391 NA -0.34 -6.24 -0.32 1.3e-9 Aortic root size; LIHC cis rs9583531 0.657 rs7318291 chr13:111352460 C/T cg24331049 chr13:111365604 ING1 -0.77 -12.3 -0.55 4.73e-29 Coronary artery disease; LIHC cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs798554 0.836 rs798502 chr7:2789880 G/T cg19346786 chr7:2764209 NA 0.39 6.12 0.31 2.54e-9 Height; LIHC cis rs7572733 0.515 rs700675 chr2:198700216 G/A cg10820045 chr2:198174542 NA 0.45 6.85 0.35 3.5e-11 Dermatomyositis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08128228 chr1:167191360 POU2F1 0.53 6.85 0.35 3.48e-11 Lung function (FEV1/FVC); LIHC cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs8177179 0.967 rs10935085 chr3:133459735 C/T cg18769074 chr3:133464867 TF 0.26 5.89 0.3 9.45e-9 Iron status biomarkers (transferrin levels); LIHC trans rs975809 0.966 rs11004607 chr10:56622686 G/T cg05965430 chr12:49962171 MCRS1 0.42 6.1 0.31 2.8e-9 Carotid intima media thickness; LIHC cis rs2257205 0.667 rs1018051 chr17:56909926 A/G cg12560992 chr17:57184187 TRIM37 0.63 7.0 0.35 1.32e-11 Pancreatic cancer; LIHC cis rs13394619 0.935 rs12468019 chr2:11725049 T/C cg07314298 chr2:11723111 GREB1 -0.49 -9.27 -0.45 2.09e-18 Endometriosis; LIHC cis rs763121 0.853 rs5750630 chr22:38985818 A/C cg14440974 chr22:39074834 NA -0.42 -6.68 -0.34 9.85e-11 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23676114 chr9:33264786 SUGT1P1;CHMP5;BAG1 0.48 6.87 0.35 3.1e-11 Pancreatic cancer; LIHC cis rs1816752 0.905 rs6490928 chr13:25014059 T/C cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC cis rs1843834 0.755 rs10197382 chr2:225574650 T/C cg22509189 chr2:225307070 NA -0.44 -5.75 -0.3 2e-8 IgE levels in asthmatics (D.p. specific); LIHC cis rs240764 0.817 rs240143 chr6:101080621 G/A cg09795085 chr6:101329169 ASCC3 0.53 7.45 0.37 7.93e-13 Neuroticism; LIHC trans rs3794271 0.706 rs9971816 chr12:20826911 C/T cg10088519 chr17:8066240 VAMP2 -0.38 -6.06 -0.31 3.51e-9 Response to TNF-alpha inhibitors in rheumatoid arthritis; LIHC cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs6860806 0.507 rs200837 chr5:131699958 G/A cg24060327 chr5:131705240 SLC22A5 -0.77 -12.07 -0.55 3.52e-28 Breast cancer; LIHC cis rs4638749 0.677 rs10203004 chr2:108826535 G/T cg06795125 chr2:108905320 SULT1C2 -0.31 -6.04 -0.31 3.92e-9 Blood pressure; LIHC cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg15691649 chr6:25882328 NA -0.64 -8.51 -0.42 5.68e-16 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg20607798 chr8:58055168 NA 0.64 7.7 0.38 1.51e-13 Developmental language disorder (linguistic errors); LIHC cis rs6665290 0.669 rs3768421 chr1:227177193 G/A cg10327440 chr1:227177885 CDC42BPA -1.13 -23.79 -0.79 1.71e-74 Myeloid white cell count; LIHC cis rs748404 0.650 rs518234 chr15:43573421 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.5 8.5 0.42 5.94e-16 Lung cancer; LIHC cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg23205692 chr1:25664452 TMEM50A 0.39 6.25 0.32 1.24e-9 Plateletcrit;Mean corpuscular volume; LIHC cis rs2842992 0.830 rs1998365 chr6:160179535 A/T cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.86 0.43 4.49e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg18230493 chr5:56204884 C5orf35 -0.47 -6.47 -0.33 3.31e-10 Initial pursuit acceleration; LIHC cis rs2832191 0.791 rs2251517 chr21:30531951 T/G cg08807101 chr21:30365312 RNF160 0.69 10.28 0.49 8.63e-22 Dental caries; LIHC cis rs7326068 0.524 rs2497484 chr13:21199265 C/T cg27234864 chr13:21295941 IL17D -0.37 -5.91 -0.3 8.25e-9 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs9858542 1.000 rs9882740 chr3:49702484 T/C cg03060546 chr3:49711283 APEH -0.62 -8.52 -0.42 5.26e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg13271783 chr10:134563150 INPP5A -0.59 -7.08 -0.36 8.16e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs7558233 0.614 rs4665214 chr2:23678795 A/G cg14793835 chr3:28283034 CMC1 0.42 6.06 0.31 3.51e-9 Cannabis use (initiation); LIHC cis rs7772486 0.875 rs2777479 chr6:146309178 C/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.95e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3806843 0.771 rs2563334 chr5:140107065 C/G cg16179182 chr5:140090404 VTRNA1-1 0.36 5.84 0.3 1.22e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.94 0.31 7.19e-9 Menopause (age at onset); LIHC cis rs10508774 0.810 rs11008965 chr10:32824451 G/T cg01819863 chr10:32635814 EPC1 0.6 5.76 0.3 1.88e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg00280220 chr17:61926910 NA 0.43 6.79 0.34 4.99e-11 Prudent dietary pattern; LIHC cis rs6952808 0.595 rs3778984 chr7:2166514 T/C cg21782813 chr7:2030301 MAD1L1 0.38 6.58 0.34 1.73e-10 Bipolar disorder and schizophrenia; LIHC cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.51 -9.0 -0.44 1.57e-17 Electroencephalogram traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07650554 chr16:30457408 SEPHS2 0.44 6.46 0.33 3.68e-10 Pancreatic cancer; LIHC cis rs7605378 0.658 rs4673507 chr2:200710167 G/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.43 5.89 0.3 9.29e-9 Osteoporosis; LIHC cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg04287289 chr16:89883240 FANCA 0.54 8.41 0.41 1.12e-15 Vitiligo; LIHC cis rs2243480 1.000 rs2707844 chr7:66059509 G/A cg12463550 chr7:65579703 CRCP 0.66 6.86 0.35 3.28e-11 Diabetic kidney disease; LIHC cis rs7666738 0.830 rs7684646 chr4:99071062 C/T cg05340658 chr4:99064831 C4orf37 0.71 13.23 0.58 1.48e-32 Colonoscopy-negative controls vs population controls; LIHC trans rs11098499 0.754 rs12506487 chr4:120271361 T/G cg25214090 chr10:38739885 LOC399744 0.44 7.28 0.37 2.26e-12 Corneal astigmatism; LIHC cis rs67311347 1.000 rs9841335 chr3:40475858 G/A cg00656387 chr3:40428638 ENTPD3 0.42 7.02 0.35 1.21e-11 Renal cell carcinoma; LIHC cis rs8103278 0.826 rs11669442 chr19:46374557 A/G cg11657440 chr19:46296263 DMWD -0.48 -7.48 -0.37 6.43e-13 Coronary artery disease; LIHC cis rs17401966 0.931 rs34225619 chr1:10371987 C/T cg19773385 chr1:10388646 KIF1B -0.48 -8.41 -0.41 1.16e-15 Hepatocellular carcinoma; LIHC cis rs875971 0.756 rs4718328 chr7:65693337 A/G cg18876405 chr7:65276391 NA -0.37 -6.53 -0.33 2.41e-10 Aortic root size; LIHC cis rs916888 0.779 rs199528 chr17:44843136 C/T cg15921436 chr17:44337874 NA 0.65 6.43 0.33 4.22e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9300255 0.566 rs10744150 chr12:123721614 A/C cg05973401 chr12:123451056 ABCB9 0.43 5.94 0.31 7.13e-9 Neutrophil percentage of white cells; LIHC cis rs919433 0.680 rs1116734 chr2:198365043 C/G cg10820045 chr2:198174542 NA 0.53 8.49 0.42 6.29e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs589448 0.872 rs315111 chr12:69784695 G/A cg14784868 chr12:69753453 YEATS4 0.97 22.07 0.77 9.37e-68 Cerebrospinal fluid biomarker levels; LIHC cis rs12497850 0.864 rs4955410 chr3:49181218 A/G cg16497277 chr3:49208875 KLHDC8B -0.48 -5.89 -0.3 9.04e-9 Parkinson's disease; LIHC cis rs7116495 0.609 rs4945378 chr11:71668866 G/A cg26138937 chr11:71823887 C11orf51 -1.31 -10.34 -0.49 5.49e-22 Severe influenza A (H1N1) infection; LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.55 7.83 0.39 6.36e-14 Lymphocyte counts; LIHC cis rs8114671 0.836 rs734308 chr20:33572096 A/G cg07148914 chr20:33460835 GGT7 -0.6 -9.18 -0.44 4.2e-18 Height; LIHC cis rs12594515 1.000 rs6493167 chr15:45986809 G/A cg19682013 chr15:45996608 NA 0.41 7.25 0.37 2.78e-12 Waist circumference;Weight; LIHC cis rs2455799 0.613 rs12637353 chr3:15831525 T/C cg12698662 chr3:15914712 MIR563 -0.39 -7.2 -0.36 3.84e-12 Mean platelet volume; LIHC trans rs73186030 0.920 rs55784797 chr3:122054635 C/T cg13973942 chr17:977984 ABR 0.47 6.06 0.31 3.54e-9 Serum parathyroid hormone levels; LIHC cis rs17826219 0.706 rs57698184 chr17:29064918 T/C cg14067834 chr17:29058358 SUZ12P 0.7 7.12 0.36 6.32e-12 Body mass index; LIHC cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg00149659 chr3:10157352 C3orf10 0.68 7.12 0.36 6.57e-12 Alzheimer's disease; LIHC cis rs17854409 0.881 rs68091818 chr20:61479882 A/C cg07645718 chr20:61493192 TCFL5 0.7 6.02 0.31 4.52e-9 Obesity-related traits; LIHC cis rs743757 1.000 rs743756 chr3:50481717 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.49 7.7 0.38 1.43e-13 Diastolic blood pressure; LIHC cis rs2072499 0.750 rs909269 chr1:156192028 C/T cg24450063 chr1:156163899 SLC25A44 0.74 7.69 0.38 1.5700000000000001e-13 Testicular germ cell tumor; LIHC cis rs7412746 0.634 rs12409208 chr1:150860055 A/G cg18016565 chr1:150552671 MCL1 0.52 9.77 0.47 4.63e-20 Melanoma; LIHC cis rs13161895 0.702 rs74507840 chr5:179487430 G/A cg06664874 chr5:179499304 RNF130 0.7 7.67 0.38 1.83e-13 LDL cholesterol; LIHC cis rs2404602 0.622 rs11632670 chr15:76974055 A/G cg03037974 chr15:76606532 NA -0.6 -10.1 -0.48 3.62e-21 Blood metabolite levels; LIHC cis rs5753037 0.809 rs2074707 chr22:30210356 G/A cg01021169 chr22:30184971 ASCC2 -0.36 -6.83 -0.35 3.97e-11 Type 1 diabetes; LIHC cis rs2933343 0.649 rs728839 chr3:128589359 A/G cg25356066 chr3:128598488 ACAD9 0.55 7.67 0.38 1.82e-13 IgG glycosylation; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg22887498 chr19:39401301 NA 0.46 6.21 0.32 1.53e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg17971929 chr21:40555470 PSMG1 -0.49 -7.52 -0.38 4.99e-13 Cognitive function; LIHC cis rs7953249 0.807 rs7310409 chr12:121424861 A/G cg02403541 chr12:121454288 C12orf43 -0.37 -6.34 -0.32 7.23e-10 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs3749237 0.595 rs7621003 chr3:49411404 T/C cg03060546 chr3:49711283 APEH 0.58 9.54 0.46 2.7e-19 Resting heart rate; LIHC cis rs4638749 0.677 rs115510885 chr2:108824365 C/T cg25838818 chr2:108905173 SULT1C2 -0.4 -7.0 -0.35 1.37e-11 Blood pressure; LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg11494091 chr17:61959527 GH2 0.36 6.04 0.31 4.13e-9 Height; LIHC cis rs68170813 0.559 rs74584447 chr7:106944755 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs72829446 0.530 rs4796430 chr17:7401903 A/G cg02795151 chr17:7402630 POLR2A 0.55 6.26 0.32 1.16e-9 Androgen levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16515820 chr3:114866447 ZBTB20 0.41 6.49 0.33 3.05e-10 Cognitive function; LIHC cis rs9733 0.596 rs6587518 chr1:150661787 T/C cg13175981 chr1:150552382 MCL1 -0.44 -6.06 -0.31 3.55e-9 Tonsillectomy; LIHC trans rs877282 1.000 rs11253369 chr10:773610 C/G cg22713356 chr15:30763199 NA 0.86 8.76 0.43 9.07e-17 Uric acid levels; LIHC cis rs3736485 0.934 rs8036821 chr15:51861646 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7447593 0.518 rs4074995 chr5:176797343 C/T cg06060754 chr5:176797920 RGS14 0.73 12.04 0.55 4.55e-28 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs509477 0.718 rs273358 chr18:32596784 C/T cg23791764 chr18:32556832 MAPRE2 0.43 5.96 0.31 6.28e-9 Cerebrospinal fluid AB1-42 levels; LIHC cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.84 0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs709400 0.628 rs10150072 chr14:103977605 C/T cg26031613 chr14:104095156 KLC1 0.72 9.14 0.44 5.86e-18 Body mass index; LIHC cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg25894440 chr7:65020034 NA -0.53 -6.11 -0.31 2.72e-9 Diabetic kidney disease; LIHC cis rs875971 0.862 rs949930 chr7:65766822 C/G cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.07e-40 Aortic root size; LIHC cis rs6499255 0.857 rs11643926 chr16:69807282 A/G cg15192750 chr16:69999425 NA 0.46 6.89 0.35 2.71e-11 IgE levels; LIHC cis rs903552 0.736 rs9806369 chr15:102008430 A/C cg06707286 chr15:102010195 PCSK6 -0.55 -7.91 -0.39 3.69e-14 Diabetic kidney disease; LIHC trans rs208520 0.690 rs1563929 chr6:66702108 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.74 8.42 0.41 1.02e-15 Exhaled nitric oxide output; LIHC cis rs57502260 0.704 rs2306862 chr11:68177510 C/T cg20283391 chr11:68216788 NA -0.48 -5.9 -0.3 8.91e-9 Total body bone mineral density (age 45-60); LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.06e-19 Renal cell carcinoma; LIHC cis rs4979906 1.000 rs7098023 chr10:79449665 A/C cg07817648 chr10:79422355 NA -0.29 -6.32 -0.32 8.17e-10 Mortality in heart failure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08949621 chr15:42265044 EHD4 0.48 6.41 0.33 4.82e-10 Lung function (FEV1/FVC); LIHC cis rs739401 0.611 rs572373 chr11:3055361 T/C cg08508325 chr11:3079039 CARS -0.32 -6.71 -0.34 8.3e-11 Longevity; LIHC cis rs12477438 0.798 rs1349779 chr2:99645055 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.26 -0.52 3.12e-25 Chronic sinus infection; LIHC cis rs10883723 0.703 rs7898410 chr10:104245858 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.08 0.58 5.63e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs769267 0.965 rs2965191 chr19:19453521 T/G cg03709012 chr19:19516395 GATAD2A -0.92 -16.02 -0.65 1.72e-43 Tonsillectomy; LIHC cis rs644799 0.710 rs10831429 chr11:95508524 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.8 12.4 0.56 2.14e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.66 0.38 1.89e-13 Prudent dietary pattern; LIHC cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.36 0.49 4.68e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7635838 0.523 rs9873503 chr3:11396100 T/C cg00170343 chr3:11313890 ATG7 0.49 7.73 0.39 1.19e-13 HDL cholesterol; LIHC trans rs875971 0.660 rs28698552 chr7:66005018 A/G cg26939375 chr7:64535504 NA 0.43 6.94 0.35 2.02e-11 Aortic root size; LIHC cis rs11628318 0.563 rs1190344 chr14:103097912 A/G cg12046867 chr14:103022105 NA -0.43 -6.69 -0.34 9.31e-11 Platelet count; LIHC cis rs4638749 0.677 rs10208945 chr2:108838593 G/C cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs853679 0.517 rs3757185 chr6:28107776 T/A cg16479474 chr6:28041457 NA 0.46 6.58 0.34 1.78e-10 Depression; LIHC cis rs1538970 0.924 rs11211111 chr1:45908782 C/T cg05343316 chr1:45956843 TESK2 0.59 8.56 0.42 3.94e-16 Platelet count; LIHC cis rs11690935 0.688 rs7600835 chr2:172521827 C/T cg13550731 chr2:172543902 DYNC1I2 -0.62 -10.69 -0.5 3.22e-23 Schizophrenia; LIHC cis rs4638749 0.677 rs6755078 chr2:108818270 T/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.99 -0.35 1.43e-11 Blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20286844 chr1:204485360 MDM4 0.5 6.92 0.35 2.21e-11 Pancreatic cancer; LIHC cis rs6690583 0.623 rs12042018 chr1:85436937 T/C cg22153463 chr1:85462885 MCOLN2 0.51 6.04 0.31 4.12e-9 Serum sulfate level; LIHC trans rs208520 0.690 rs851465 chr6:66840293 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.33 -0.41 1.94e-15 Exhaled nitric oxide output; LIHC cis rs826838 0.967 rs6580726 chr12:39108623 T/C cg26384229 chr12:38710491 ALG10B -0.56 -8.32 -0.41 2.16e-15 Heart rate; LIHC cis rs763121 0.853 rs3788544 chr22:39064966 C/T cg14440974 chr22:39074834 NA -0.44 -7.11 -0.36 6.7e-12 Menopause (age at onset); LIHC cis rs2180341 0.782 rs4487601 chr6:127723521 A/G cg24812749 chr6:127587940 RNF146 0.79 12.47 0.56 1.1e-29 Breast cancer; LIHC trans rs1814175 0.684 rs1827015 chr11:49585241 A/G cg15704280 chr7:45808275 SEPT13 -0.93 -17.78 -0.69 1.56e-50 Height; LIHC cis rs2257205 0.667 rs6503881 chr17:56911251 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -6.51 -0.33 2.72e-10 Pancreatic cancer; LIHC cis rs9916302 0.851 rs11870631 chr17:37645129 C/T cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC cis rs875971 0.660 rs12698534 chr7:65986845 C/T cg14393609 chr7:65229607 NA 0.37 5.84 0.3 1.22e-8 Aortic root size; LIHC cis rs7312933 1.000 rs12372623 chr12:42531666 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.49 7.08 0.36 8.05e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10791097 0.739 rs735094 chr11:130725109 G/C cg14779329 chr11:130786720 SNX19 0.39 5.84 0.3 1.22e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs968567 0.705 rs174573 chr11:61600327 G/A cg27386326 chr11:61587980 NA 0.47 6.8 0.35 4.71e-11 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs3736485 0.652 rs2054166 chr15:51974910 A/T cg08986416 chr15:51914746 DMXL2 -0.43 -6.27 -0.32 1.1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6565180 0.791 rs4247355 chr16:30392099 A/G cg17640201 chr16:30407289 ZNF48 0.77 12.78 0.57 7.9e-31 Tonsillectomy; LIHC cis rs9916302 0.904 rs8065963 chr17:37681332 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.37 -0.59 4.35e-33 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg00656387 chr3:40428638 ENTPD3 0.41 6.88 0.35 2.95e-11 Renal cell carcinoma; LIHC cis rs7131987 0.903 rs11050163 chr12:29420398 C/T cg00204748 chr12:29376779 FAR2 0.43 8.05 0.4 1.43e-14 QT interval; LIHC trans rs3780486 0.801 rs3780495 chr9:33125942 A/C cg04842962 chr6:43655489 MRPS18A 1.07 25.45 0.81 6.59e-81 IgG glycosylation; LIHC cis rs1865721 1.000 rs1865721 chr18:73192446 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.17e-13 Intelligence; LIHC cis rs17095355 1.000 rs12246851 chr10:111726340 C/T cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.95 -0.31 6.71e-9 Biliary atresia; LIHC cis rs1691799 0.867 rs1168347 chr12:66757303 T/C cg16791601 chr12:66731901 HELB -0.52 -12.18 -0.55 1.35e-28 White blood cell count (basophil); LIHC cis rs6570726 0.791 rs441290 chr6:145883183 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.79 -0.3 1.64e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg12463550 chr7:65579703 CRCP 0.68 7.14 0.36 5.69e-12 Diabetic kidney disease; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg00933542 chr6:150070202 PCMT1 0.34 5.81 0.3 1.42e-8 Lung cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25880573 chr1:24073129 TCEB3 -0.36 -6.37 -0.33 5.93e-10 Pancreatic cancer; LIHC cis rs7520050 0.966 rs4660910 chr1:46548402 G/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.84 0.3 1.19e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7044106 0.791 rs7036766 chr9:123479621 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.28 0.52 2.62e-25 Hip circumference adjusted for BMI; LIHC cis rs6815814 0.950 rs11722788 chr4:38810738 C/G cg06935464 chr4:38784597 TLR10 0.46 7.19 0.36 4.1e-12 Breast cancer; LIHC cis rs75908454 1.000 rs75908454 chr6:169970623 T/C cg19338460 chr6:170058176 WDR27 -0.62 -6.01 -0.31 4.63e-9 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs57244997 0.725 rs73785320 chr6:162439590 A/C cg17173639 chr6:162384350 PARK2 -0.51 -6.68 -0.34 9.43e-11 Mosquito bite size; LIHC cis rs149163995 1 rs149163995 chr2:203777226 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Migraine; LIHC cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg13271783 chr10:134563150 INPP5A -0.52 -6.75 -0.34 6.38e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs28830936 1.000 rs9672298 chr15:41912368 A/C cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.06 -0.31 3.64e-9 Diastolic blood pressure; LIHC cis rs7044106 0.791 rs4617229 chr9:123480696 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.36 0.37 1.34e-12 Hip circumference adjusted for BMI; LIHC cis rs12477438 0.765 rs9710648 chr2:99673129 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs6733011 0.506 rs11123755 chr2:99507948 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.45 -6.47 -0.33 3.35e-10 Bipolar disorder; LIHC cis rs17401966 1.000 rs11121552 chr1:10435324 C/A cg19773385 chr1:10388646 KIF1B -0.52 -8.58 -0.42 3.31e-16 Hepatocellular carcinoma; LIHC cis rs7904368 0.806 rs1130684 chr10:16859335 C/G cg14835575 chr10:16859367 RSU1 0.68 10.05 0.48 5.41e-21 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC trans rs6598955 0.671 rs12354062 chr1:26608761 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg06640241 chr16:89574553 SPG7 -0.8 -15.07 -0.63 9.94e-40 Multiple myeloma (IgH translocation); LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg14709524 chr16:89940631 TCF25 0.59 7.63 0.38 2.43e-13 Skin colour saturation; LIHC cis rs11233413 0.559 rs11233391 chr11:82683038 A/C cg24227371 chr11:82718527 RAB30 -0.33 -7.35 -0.37 1.44e-12 Economic and political preferences (feminism/equality); LIHC cis rs903552 1.000 rs8027380 chr15:102005810 T/C cg19295451 chr15:102010161 PCSK6 -0.46 -6.33 -0.32 7.51e-10 Diabetic kidney disease; LIHC cis rs79976124 0.719 rs34488909 chr6:66637850 T/C cg07460842 chr6:66804631 NA 0.67 7.22 0.36 3.48e-12 Type 2 diabetes; LIHC cis rs13108904 0.557 rs1680041 chr4:1238521 C/T cg05025164 chr4:1340916 KIAA1530 -0.66 -9.93 -0.47 1.36e-20 Obesity-related traits; LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs1843834 1.000 rs1565072 chr2:225545245 C/T cg22509189 chr2:225307070 NA 0.56 7.19 0.36 4.07e-12 IgE levels in asthmatics (D.p. specific); LIHC cis rs400736 0.526 rs10864329 chr1:8164460 G/A cg25007680 chr1:8021821 PARK7 -0.48 -7.22 -0.36 3.31e-12 Response to antidepressants and depression; LIHC cis rs2576037 0.526 rs2571027 chr18:44561516 C/G cg19077165 chr18:44547161 KATNAL2 0.43 6.49 0.33 3.09e-10 Personality dimensions; LIHC cis rs2421770 0.530 rs7930134 chr11:35367017 A/C cg13971030 chr11:35366721 SLC1A2 -0.45 -7.59 -0.38 3.02e-13 Staphylococcus aureus nasal carriage (persistent); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16266895 chr12:101674004 UTP20 0.44 6.3 0.32 9.28e-10 Pancreatic cancer; LIHC cis rs40363 0.523 rs757270 chr16:3534451 C/T cg00484396 chr16:3507460 NAT15 -0.37 -6.53 -0.33 2.38e-10 Tuberculosis; LIHC cis rs244293 0.760 rs4794547 chr17:53011172 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.48 -7.31 -0.37 1.9e-12 Menarche (age at onset); LIHC cis rs6089584 0.888 rs6587283 chr20:60613727 A/C cg23262073 chr20:60523788 NA -0.29 -5.94 -0.31 6.89e-9 Body mass index; LIHC cis rs12915845 0.545 rs17197019 chr15:89079672 C/T cg05013243 chr15:89149849 MIR1179 0.37 6.74 0.34 6.56e-11 Menarche (age at onset); LIHC cis rs4665809 0.878 rs6748745 chr2:26364190 C/T cg27170947 chr2:26402098 FAM59B -0.69 -8.54 -0.42 4.58e-16 Gut microbiome composition (summer); LIHC cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs910316 0.763 rs1548807 chr14:75479582 T/G cg08847533 chr14:75593920 NEK9 0.9 18.89 0.71 5.17e-55 Height; LIHC cis rs1983891 0.874 rs2395779 chr6:41511950 C/T cg20194872 chr6:41519635 FOXP4 0.42 6.86 0.35 3.23e-11 Prostate cancer; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17360233 chr16:10479841 NA 0.42 6.35 0.32 6.89e-10 Alopecia areata; LIHC cis rs10276381 1.000 rs10276381 chr7:28190121 A/G cg23620719 chr7:28220237 JAZF1 -0.61 -7.58 -0.38 3.21e-13 Crohn's disease; LIHC cis rs11122272 0.735 rs2486741 chr1:231516450 G/C cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC trans rs11098499 0.954 rs17009122 chr4:120362403 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg08645402 chr16:4508243 NA 0.47 9.0 0.44 1.63e-17 Schizophrenia; LIHC cis rs798554 0.679 rs7784066 chr7:2819727 T/A cg19346786 chr7:2764209 NA -0.43 -6.53 -0.33 2.32e-10 Height; LIHC cis rs67478160 0.619 rs12886363 chr14:104273786 T/C cg24130564 chr14:104152367 KLC1 -0.35 -5.74 -0.3 2.07e-8 Schizophrenia; LIHC cis rs17685 0.725 rs6467993 chr7:75719350 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.21 -0.32 1.52e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs57590327 0.503 rs9874464 chr3:81505488 C/G cg07356753 chr3:81810745 GBE1 -0.47 -7.02 -0.35 1.2e-11 Extraversion; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg20612964 chr1:1668511 SLC35E2 0.43 6.73 0.34 7.27e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 6e-11 Prudent dietary pattern; LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs7312933 0.585 rs7969814 chr12:42669657 C/G cg01256987 chr12:42539512 GXYLT1 -0.4 -6.64 -0.34 1.2e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs950169 0.723 rs17589320 chr15:84919996 C/A cg03959625 chr15:84868606 LOC388152 0.46 6.65 0.34 1.14e-10 Schizophrenia; LIHC cis rs449303 1 rs449303 chr14:60605788 A/G cg18906360 chr14:60633047 DHRS7 0.51 6.26 0.32 1.13e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs77861329 1.000 rs183029 chr3:52209884 A/G cg08692210 chr3:52188851 WDR51A 0.79 7.52 0.38 4.79e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs7246657 0.943 rs8111782 chr19:37867904 A/G cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg01806965 chr8:144378397 ZNF696 0.42 6.53 0.33 2.42e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs1348850 0.598 rs12616259 chr2:178503803 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.82 0.39 6.66e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs67478160 0.643 rs12878868 chr14:104233725 G/A cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.83 -0.39 6.23e-14 Schizophrenia; LIHC cis rs8081395 0.801 rs2665404 chr17:57875396 A/G cg13753209 chr17:57696993 CLTC 0.45 6.99 0.35 1.48e-11 White blood cell count; LIHC cis rs9790314 0.967 rs10804790 chr3:161039300 T/A cg04691961 chr3:161091175 C3orf57 -0.42 -6.48 -0.33 3.21e-10 Morning vs. evening chronotype; LIHC cis rs2842992 0.830 rs2758352 chr6:160122921 A/G cg11366901 chr6:160182831 ACAT2 0.94 15.56 0.64 1.17e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs2576037 0.544 rs629097 chr18:44378097 T/C cg19077165 chr18:44547161 KATNAL2 -0.46 -6.82 -0.35 4.26e-11 Personality dimensions; LIHC cis rs11971779 0.680 rs4398844 chr7:139043139 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.16 0.48 2.33e-21 Diisocyanate-induced asthma; LIHC cis rs10883723 0.810 rs11191304 chr10:104255284 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7119038 0.818 rs1048024 chr11:118618776 A/T cg19308663 chr11:118741387 NA 0.43 5.79 0.3 1.56e-8 Sjögren's syndrome; LIHC cis rs4665809 1.000 rs6546766 chr2:26328680 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs2074038 1.000 rs2074038 chr11:44087989 G/T cg17479956 chr11:44115929 EXT2 0.46 5.81 0.3 1.45e-8 IgA nephropathy; LIHC cis rs72781680 0.898 rs56413706 chr2:24086961 G/A cg08917208 chr2:24149416 ATAD2B 0.99 8.7 0.43 1.39e-16 Lymphocyte counts; LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg24503407 chr1:205819492 PM20D1 0.73 10.37 0.49 4.46e-22 Menarche (age at onset); LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.98 -0.4 2.21e-14 Lymphocyte counts; LIHC trans rs877282 0.947 rs957642 chr10:773966 C/T cg22713356 chr15:30763199 NA 1.09 9.99 0.48 8.38e-21 Uric acid levels; LIHC cis rs782590 0.967 rs62165172 chr2:55736237 A/G cg18811423 chr2:55921094 PNPT1 0.95 14.75 0.62 1.81e-38 Metabolic syndrome; LIHC cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg13126279 chr21:47581558 C21orf56 -0.44 -6.9 -0.35 2.46e-11 Testicular germ cell tumor; LIHC cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg05754148 chr16:3507555 NAT15 0.38 6.25 0.32 1.19e-9 Tuberculosis; LIHC cis rs9560113 1.000 rs4771757 chr13:112176379 G/T cg14154082 chr13:112174009 NA 0.29 6.14 0.32 2.28e-9 Menarche (age at onset); LIHC cis rs477895 0.713 rs11600867 chr11:63972052 T/A cg05555928 chr11:63887634 MACROD1 0.52 6.75 0.34 6.22e-11 Mean platelet volume; LIHC cis rs881375 0.967 rs1008381 chr9:123681116 T/C cg14580859 chr9:123691850 NA 0.38 6.68 0.34 9.57e-11 Rheumatoid arthritis; LIHC cis rs9929218 1.000 rs12921546 chr16:68780069 G/A cg01231543 chr16:68741748 NA 0.37 5.88 0.3 9.91e-9 Colorectal cancer; LIHC cis rs4788570 0.566 rs1804984 chr16:71481520 T/A cg06353428 chr16:71660113 MARVELD3 -1.13 -10.2 -0.48 1.67e-21 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.534 rs4931772 chr12:34044590 G/A cg26384229 chr12:38710491 ALG10B 0.45 6.41 0.33 4.71e-10 Morning vs. evening chronotype; LIHC trans rs2727020 0.658 rs4980431 chr11:49350071 G/T cg03929089 chr4:120376271 NA -0.83 -14.81 -0.63 1.06e-38 Coronary artery disease; LIHC cis rs2712381 0.797 rs62270806 chr3:128376269 C/T cg16766828 chr3:128327626 NA -0.41 -6.46 -0.33 3.51e-10 Monocyte count; LIHC cis rs7772486 0.597 rs2485631 chr6:146190077 G/C cg13319975 chr6:146136371 FBXO30 -0.57 -9.03 -0.44 1.29e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg06238570 chr21:40685208 BRWD1 0.56 6.59 0.34 1.71e-10 Cognitive function; LIHC cis rs4819052 0.851 rs4819040 chr21:46659762 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.67 0.5 3.91e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12701220 0.725 rs13242971 chr7:1055515 C/T cg00990874 chr7:1149470 C7orf50 -0.7 -9.77 -0.47 4.94e-20 Bronchopulmonary dysplasia; LIHC cis rs11792861 0.591 rs10979613 chr9:111687584 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.68 11.35 0.52 1.51e-25 Menarche (age at onset); LIHC cis rs3784262 1.000 rs3204689 chr15:58246802 G/C cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.22 -0.32 1.42e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs3743266 0.507 rs9630426 chr15:60739053 C/T cg22293140 chr15:60689852 ANXA2 -0.62 -6.01 -0.31 4.69e-9 Menarche (age at onset); LIHC cis rs6570726 0.846 rs441575 chr6:145849205 A/C cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs2727020 0.894 rs1917328 chr11:49359606 G/A cg03929089 chr4:120376271 NA -0.65 -9.66 -0.46 1.13e-19 Coronary artery disease; LIHC trans rs75804782 0.641 rs2340870 chr2:239356026 C/T cg01134436 chr17:81009848 B3GNTL1 0.8 6.79 0.34 4.97e-11 Morning vs. evening chronotype;Chronotype; LIHC trans rs75804782 0.521 rs72982590 chr2:239451826 T/C cg01134436 chr17:81009848 B3GNTL1 0.74 6.27 0.32 1.11e-9 Morning vs. evening chronotype;Chronotype; LIHC cis rs12586317 0.547 rs28395170 chr14:35506988 C/T cg05294307 chr14:35346193 BAZ1A -0.49 -7.16 -0.36 5.09e-12 Psoriasis; LIHC cis rs57590327 0.679 rs35381070 chr3:81590374 G/A cg07356753 chr3:81810745 GBE1 -0.47 -6.44 -0.33 4e-10 Extraversion; LIHC cis rs3096299 0.967 rs2965935 chr16:89481274 C/T cg08392591 chr16:89556376 ANKRD11 -0.39 -5.84 -0.3 1.24e-8 Multiple myeloma (IgH translocation); LIHC cis rs9296404 1 rs9296404 chr6:42925803 T/C cg24101359 chr6:42928495 GNMT 0.46 6.25 0.32 1.19e-9 Plasma homocysteine levels (post-methionine load test); LIHC cis rs9303401 0.592 rs66583824 chr17:56639853 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs6951245 0.572 rs74791540 chr7:1061913 C/A cg24642844 chr7:1081250 C7orf50 -0.8 -6.71 -0.34 8.11e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11125080 0.735 rs7609080 chr2:46733783 A/G cg02822958 chr2:46747628 ATP6V1E2 0.56 6.39 0.33 5.33e-10 Anti-saccade response;Anti-saccade error rate in psychotic disorders; LIHC cis rs10193935 0.901 rs1439231 chr2:42542884 G/A cg27598129 chr2:42591480 NA -0.71 -11.2 -0.52 5.04e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs2455799 0.613 rs2166759 chr3:15856285 A/G cg12698662 chr3:15914712 MIR563 0.37 6.83 0.35 3.78e-11 Mean platelet volume; LIHC cis rs7474896 0.559 rs1208560 chr10:38221618 A/T cg25427524 chr10:38739819 LOC399744 0.45 5.92 0.3 7.91e-9 Obesity (extreme); LIHC trans rs4714291 0.722 rs9296320 chr6:40118298 C/G cg02267698 chr19:7991119 CTXN1 0.36 6.1 0.31 2.85e-9 Strep throat; LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.59 8.97 0.44 2.02e-17 Height; LIHC cis rs7959452 0.535 rs11177577 chr12:69671791 C/T cg22834771 chr12:69754056 YEATS4 -0.5 -8.44 -0.41 9.43e-16 Blood protein levels; LIHC cis rs5758659 0.904 rs134877 chr22:42662371 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.38 -7.39 -0.37 1.14e-12 Cognitive function; LIHC trans rs412658 0.668 rs7253490 chr19:22293706 A/C cg17074339 chr11:11642133 GALNTL4 0.44 6.77 0.34 5.71e-11 Telomere length; LIHC cis rs12824058 0.831 rs12300308 chr12:130813825 G/A cg26677194 chr12:130822605 PIWIL1 0.51 7.17 0.36 4.75e-12 Menopause (age at onset); LIHC cis rs807029 0.758 rs807025 chr10:102764821 C/T cg17130504 chr10:102756923 LZTS2 0.43 5.77 0.3 1.8e-8 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7312933 0.584 rs6582391 chr12:42634686 G/A cg17420585 chr12:42539391 GXYLT1 -0.36 -5.87 -0.3 1.01e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1983891 0.874 rs3747744 chr6:41516351 A/G cg15051332 chr6:41514432 FOXP4 0.42 5.83 0.3 1.31e-8 Prostate cancer; LIHC cis rs875971 0.545 rs11767262 chr7:65767224 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.51 0.38 5.34e-13 Aortic root size; LIHC trans rs7385804 0.727 rs551238 chr7:100321528 G/T cg02228481 chr6:31165922 HCG27 -0.46 -6.09 -0.31 3e-9 Iron status biomarkers;Mean corpuscular hemoglobin;Hematocrit;Iron status biomarkers (transferrin saturation);Red blood cell count;Iron status biomarkers (iron levels);Mean corpuscular volume;Hematological parameters; LIHC cis rs61990749 0.597 rs759808 chr14:78250845 T/G cg23188588 chr14:78226832 SNW1;C14orf178 0.6 10.11 0.48 3.28e-21 Fibroblast growth factor basic levels; LIHC cis rs7917772 0.636 rs7079231 chr10:104527341 A/G cg22532475 chr10:104410764 TRIM8 -0.35 -6.41 -0.33 4.73e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9911578 1.000 rs2611782 chr17:56717956 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs798554 0.524 rs2283784 chr7:2855337 T/C cg19717773 chr7:2847554 GNA12 -0.42 -7.52 -0.38 4.72e-13 Height; LIHC cis rs9457247 0.765 rs9457252 chr6:167433925 A/G cg23791538 chr6:167370224 RNASET2 0.53 8.25 0.41 3.4e-15 Crohn's disease; LIHC cis rs10744422 1.000 rs1587856 chr12:123342229 A/G cg25930673 chr12:123319894 HIP1R -0.95 -12.64 -0.56 2.48e-30 Schizophrenia; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg13390998 chr8:145670370 NFKBIL2 -0.4 -6.05 -0.31 3.89e-9 Body mass index; LIHC cis rs738322 0.600 rs6001030 chr22:38555904 T/G cg25457927 chr22:38595422 NA -0.31 -6.88 -0.35 2.9e-11 Cutaneous nevi; LIHC cis rs6882046 0.513 rs639725 chr5:88001969 A/G cg22951263 chr5:87985283 NA -0.39 -6.89 -0.35 2.7e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs9549367 0.789 rs2302754 chr13:113898385 C/T cg18105134 chr13:113819100 PROZ 0.67 11.77 0.54 4.38e-27 Platelet distribution width; LIHC cis rs2429369 0.528 rs2526376 chr17:56427142 A/C cg12560992 chr17:57184187 TRIM37 0.67 9.61 0.46 1.67e-19 Cognitive function; LIHC trans rs72632736 1.000 rs72632731 chr1:4445471 C/T cg21153040 chr19:13985688 MIR181D -0.45 -6.07 -0.31 3.3e-9 Systemic juvenile idiopathic arthritis; LIHC cis rs9790314 1.000 rs460508 chr3:161091089 C/G cg04691961 chr3:161091175 C3orf57 0.42 6.75 0.34 6.42e-11 Morning vs. evening chronotype; LIHC cis rs61776719 0.738 rs7555461 chr1:38444749 T/C cg17077180 chr1:38461687 NA -0.4 -6.44 -0.33 4.02e-10 Coronary artery disease; LIHC cis rs74544699 1.000 rs116433096 chr4:74775629 C/T cg02530824 chr4:74847766 PF4 0.54 6.1 0.31 2.81e-9 Growth-regulated protein alpha levels; LIHC cis rs2153535 0.547 rs9505475 chr6:8542890 A/G cg07606381 chr6:8435919 SLC35B3 0.78 11.28 0.52 2.74e-25 Motion sickness; LIHC cis rs8017423 0.967 rs11159957 chr14:90715972 A/G cg14092571 chr14:90743983 NA 0.39 6.31 0.32 8.75e-10 Mortality in heart failure; LIHC cis rs2439831 1.000 rs565007 chr15:43716641 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.94 0.44 2.46e-17 Lung cancer in ever smokers; LIHC cis rs4722404 0.502 rs13223548 chr7:3110446 T/C cg19214707 chr7:3157722 NA -0.34 -5.85 -0.3 1.13e-8 Atopic dermatitis; LIHC cis rs1865760 0.964 rs3799373 chr6:25929173 A/C cg12310025 chr6:25882481 NA -0.38 -5.73 -0.3 2.26e-8 Height; LIHC cis rs17253792 0.822 rs10129890 chr14:56040413 A/T cg01858014 chr14:56050164 KTN1 -0.7 -7.17 -0.36 4.59e-12 Putamen volume; LIHC cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg23205692 chr1:25664452 TMEM50A 0.39 6.41 0.33 4.69e-10 Erythrocyte sedimentation rate; LIHC cis rs2075371 1.000 rs7486 chr7:133975183 A/G cg11752832 chr7:134001865 SLC35B4 0.48 7.36 0.37 1.34e-12 Mean platelet volume; LIHC cis rs919433 0.680 rs1116734 chr2:198365043 C/G cg03934865 chr2:198174659 NA 0.53 8.19 0.41 5.14e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs13191362 1.000 rs34066731 chr6:163011047 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10751667 0.666 rs12295141 chr11:947065 G/A cg10932868 chr11:921992 NA 0.4 7.54 0.38 4.38e-13 Alzheimer's disease (late onset); LIHC cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg11062466 chr8:58055876 NA 0.52 7.54 0.38 4.33e-13 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.601 rs2327091 chr6:8540369 G/A cg07606381 chr6:8435919 SLC35B3 0.8 11.6 0.53 1.82e-26 Motion sickness; LIHC cis rs72781680 1.000 rs72781683 chr2:24247423 T/C cg08917208 chr2:24149416 ATAD2B 0.81 6.26 0.32 1.17e-9 Lymphocyte counts; LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg26354017 chr1:205819088 PM20D1 0.84 12.17 0.55 1.49e-28 Menarche (age at onset); LIHC trans rs11098499 0.754 rs1980027 chr4:120251577 C/T cg25214090 chr10:38739885 LOC399744 0.5 8.18 0.4 5.7e-15 Corneal astigmatism; LIHC cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg23758822 chr17:41437982 NA 0.94 17.56 0.69 1.12e-49 Menopause (age at onset); LIHC cis rs7914558 1.000 rs7911789 chr10:104756374 T/C cg15744005 chr10:104629667 AS3MT -0.36 -8.05 -0.4 1.4e-14 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6500602 0.627 rs709632 chr16:4587811 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.45 -6.55 -0.33 2.08e-10 Schizophrenia; LIHC cis rs10540 0.749 rs61877777 chr11:526356 G/A cg03576123 chr11:487126 PTDSS2 -1.0 -7.11 -0.36 6.81e-12 Body mass index; LIHC cis rs12477438 0.520 rs6542866 chr2:99764592 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.6 11.19 0.52 5.77e-25 Chronic sinus infection; LIHC cis rs9486719 0.857 rs9285393 chr6:97020917 C/A cg06623918 chr6:96969491 KIAA0776 -0.67 -7.05 -0.36 1e-11 Migraine;Coronary artery disease; LIHC cis rs7582720 1.000 rs72928620 chr2:203840973 G/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.34 0.32 7.17e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2153535 0.580 rs1115078 chr6:8449638 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.66 -10.85 -0.51 9.38e-24 Colorectal cancer; LIHC cis rs3015497 0.752 rs6572682 chr14:51144800 A/T cg09863266 chr14:51125203 SAV1 -0.39 -6.27 -0.32 1.07e-9 Mean platelet volume; LIHC cis rs7937890 0.874 rs2303972 chr11:14303282 T/A cg02251663 chr11:14281053 SPON1 0.48 6.47 0.33 3.36e-10 Mitochondrial DNA levels; LIHC cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg00204748 chr12:29376779 FAR2 0.45 8.58 0.42 3.35e-16 QT interval; LIHC cis rs7587476 0.784 rs13008641 chr2:215698033 T/C cg04530015 chr2:215796436 ABCA12 -0.39 -6.39 -0.33 5.58e-10 Neuroblastoma; LIHC cis rs9818758 0.607 rs11706052 chr3:49064110 A/G cg06212747 chr3:49208901 KLHDC8B -0.69 -5.91 -0.3 8.11e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.73 0.39 1.24e-13 Electroencephalogram traits; LIHC cis rs67311347 1.000 rs6762997 chr3:40478151 C/T cg09455208 chr3:40491958 NA 0.34 6.94 0.35 1.97e-11 Renal cell carcinoma; LIHC trans rs12478296 0.901 rs7603560 chr2:243043256 C/T cg01596870 chr19:55963115 NA -0.62 -7.38 -0.37 1.23e-12 Obesity-related traits; LIHC cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg27286337 chr10:134555280 INPP5A 0.95 13.48 0.59 1.68e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs1728785 0.688 rs698729 chr16:68624205 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.19 0.32 1.74e-9 Ulcerative colitis; LIHC cis rs7100689 0.622 rs1340373 chr10:82129250 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs10503871 0.625 rs4292648 chr8:30324803 C/T cg26383811 chr8:30366931 RBPMS 0.45 7.82 0.39 6.51e-14 Metabolite levels (X-11787); LIHC cis rs2243480 0.901 rs778732 chr7:65822360 C/T cg12463550 chr7:65579703 CRCP 0.65 6.87 0.35 3.1e-11 Diabetic kidney disease; LIHC cis rs2404602 0.583 rs12438741 chr15:76542114 C/A cg03037974 chr15:76606532 NA 0.88 22.28 0.77 1.42e-68 Blood metabolite levels; LIHC cis rs12971120 0.891 rs12605820 chr18:72167802 G/A cg26446133 chr18:72167187 CNDP2 -0.8 -14.44 -0.62 3.07e-37 Refractive error; LIHC cis rs10751667 0.580 rs10751664 chr11:927077 T/G cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC cis rs35110281 0.591 rs189094 chr21:44932017 A/G cg21573476 chr21:45109991 RRP1B -0.48 -8.32 -0.41 2.08e-15 Mean corpuscular volume; LIHC cis rs765787 0.530 rs2413780 chr15:45538866 A/G cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs6429082 0.608 rs4659838 chr1:235565315 A/G cg26050004 chr1:235667680 B3GALNT2 -0.44 -6.63 -0.34 1.3100000000000001e-10 Adiposity; LIHC cis rs2404602 0.583 rs2456076 chr15:76557553 T/G cg22467129 chr15:76604101 ETFA 0.36 6.07 0.31 3.48e-9 Blood metabolite levels; LIHC cis rs6546550 0.935 rs10865380 chr2:70091246 T/C cg02498382 chr2:70120550 SNRNP27 -0.38 -6.35 -0.32 6.83e-10 Prevalent atrial fibrillation; LIHC cis rs3823572 0.564 rs10272509 chr7:133636302 A/G cg03336402 chr7:133662267 EXOC4 0.47 5.84 0.3 1.22e-8 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs10440301 chr4:17663199 G/A cg16339924 chr4:17578868 LAP3 0.52 6.84 0.35 3.73e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg12310025 chr6:25882481 NA -1.18 -19.12 -0.72 5.96e-56 Urate levels; LIHC cis rs56235845 0.694 rs11749830 chr5:176766547 G/A cg06060754 chr5:176797920 RGS14 0.47 6.72 0.34 7.41e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs8078723 0.690 rs56326707 chr17:38130139 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.6 -10.05 -0.48 5.49e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg13866156 chr1:1669148 SLC35E2 0.61 10.12 0.48 3.13e-21 Body mass index; LIHC cis rs11122272 0.701 rs2749702 chr1:231523808 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs2832191 0.935 rs11910475 chr21:30519702 T/C cg24692254 chr21:30365293 RNF160 -0.52 -9.1 -0.44 7.36e-18 Dental caries; LIHC cis rs4819052 0.851 rs2838858 chr21:46681093 T/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.64 0.53 1.3e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2067615 0.507 rs10746063 chr12:107086240 G/T cg15890332 chr12:107067104 RFX4 0.27 6.31 0.32 8.71e-10 Heart rate; LIHC cis rs11958404 0.932 rs72816583 chr5:157432647 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs28595532 0.748 rs72670258 chr4:119391660 A/T cg21605333 chr4:119757512 SEC24D 1.03 7.8 0.39 7.67e-14 Cannabis dependence symptom count; LIHC cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.89 -0.3 9.34e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.81 10.28 0.49 9.09e-22 Alzheimer's disease; LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg08280861 chr8:58055591 NA 0.49 6.11 0.31 2.69e-9 Developmental language disorder (linguistic errors); LIHC cis rs778371 0.676 rs921055 chr2:233697337 A/C cg08000102 chr2:233561755 GIGYF2 -0.77 -9.44 -0.45 5.92e-19 Schizophrenia; LIHC cis rs600806 0.713 rs10745305 chr1:110012148 A/G cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.34 -0.32 7.42e-10 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.903 rs7077278 chr10:911291 A/G cg20503657 chr10:835505 NA -1.11 -12.94 -0.57 1.82e-31 Eosinophil percentage of granulocytes; LIHC cis rs6748734 1.000 rs4675868 chr2:241828542 A/C cg04034577 chr2:241836375 C2orf54 -0.4 -8.11 -0.4 9.08e-15 Urinary metabolites; LIHC cis rs12731740 0.908 rs12568382 chr1:207966393 C/T cg22525895 chr1:207977042 MIR29B2 -0.49 -5.74 -0.3 2.14e-8 Biomedical quantitative traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11599998 chr3:160283537 KPNA4 0.45 6.42 0.33 4.68e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.642 rs11189167 chr10:99125722 A/G cg06359132 chr10:99160096 RRP12 -0.39 -5.72 -0.3 2.38e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs2346177 0.874 rs4953372 chr2:46651624 C/G cg02822958 chr2:46747628 ATP6V1E2 -0.39 -5.96 -0.31 6.14e-9 HDL cholesterol; LIHC cis rs7020830 0.867 rs56098516 chr9:37362220 A/G cg14294708 chr9:37120828 ZCCHC7 1.04 21.1 0.75 7.19e-64 Schizophrenia; LIHC cis rs6089829 0.890 rs6062775 chr20:61663650 T/C cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs9399137 0.507 rs7761964 chr6:135314265 T/C cg24558204 chr6:135376177 HBS1L 0.61 10.4 0.49 3.53e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs2427308 0.607 rs1741635 chr20:60938197 C/G cg06026331 chr20:60912101 LAMA5 -0.55 -6.74 -0.34 6.76e-11 Colorectal cancer; LIHC cis rs2806561 0.964 rs683052 chr1:23514953 T/C cg19743168 chr1:23544995 NA 0.4 7.67 0.38 1.8e-13 Height; LIHC cis rs3806843 0.619 rs2569160 chr5:140028774 T/C cg19875535 chr5:140030758 IK -0.42 -6.88 -0.35 2.85e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs7707921 0.881 rs111907176 chr5:81312399 A/G cg15871215 chr5:81402204 ATG10 -0.64 -6.34 -0.32 7.41e-10 Breast cancer; LIHC trans rs7618501 0.633 rs4688690 chr3:50022292 G/A cg21659725 chr3:3221576 CRBN 0.69 11.22 0.52 4.43e-25 Intelligence (multi-trait analysis); LIHC cis rs10267417 0.514 rs2072184 chr7:19748883 A/G cg07541023 chr7:19748670 TWISTNB 0.89 19.43 0.72 3.6e-57 Night sleep phenotypes; LIHC cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg20607798 chr8:58055168 NA 0.49 6.21 0.32 1.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs2732480 0.577 rs2634684 chr12:48730875 C/T cg21466736 chr12:48725269 NA 0.71 10.9 0.51 6.09e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg18866267 chr4:3310044 NA 0.41 6.29 0.32 9.91e-10 Bilirubin levels; LIHC trans rs9929218 0.954 rs9928796 chr16:68820718 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -8.65 -0.42 2.1e-16 Colorectal cancer; LIHC cis rs2281845 0.507 rs10800760 chr1:201100439 G/A cg06714761 chr1:201096289 NA 0.35 5.93 0.31 7.23e-9 Permanent tooth development; LIHC cis rs1059312 0.808 rs4760537 chr12:129301299 C/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.78 -17.0 -0.68 2.14e-47 Systemic lupus erythematosus; LIHC cis rs11112613 0.609 rs4991814 chr12:106046709 G/A cg03607813 chr12:105948248 NA 0.4 6.27 0.32 1.11e-9 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs9733 0.570 rs951281 chr1:150691122 A/C cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs7945705 0.747 rs10840158 chr11:9020897 A/C cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -7.34 -0.37 1.55e-12 Hemoglobin concentration; LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg09177884 chr7:1199841 ZFAND2A -0.44 -6.31 -0.32 8.8e-10 Longevity;Endometriosis; LIHC cis rs11785693 0.819 rs6994891 chr8:4989856 T/A cg26367366 chr8:4980734 NA 0.6 6.32 0.32 8.05e-10 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs1215050 0.740 rs6855827 chr4:99065706 G/A cg05340658 chr4:99064831 C4orf37 0.4 6.15 0.32 2.22e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7772486 0.790 rs4314514 chr6:146260010 A/G cg23711669 chr6:146136114 FBXO30 -0.64 -11.17 -0.52 6.66e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs1728785 1.000 rs821167 chr16:68577222 T/G cg02972257 chr16:68554789 NA -0.56 -6.26 -0.32 1.15e-9 Ulcerative colitis; LIHC cis rs796364 0.616 rs6710393 chr2:200697246 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.65 6.99 0.35 1.45e-11 Schizophrenia; LIHC cis rs2576037 0.526 rs2510444 chr18:44376849 G/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.25 -0.36 2.86e-12 Personality dimensions; LIHC trans rs1005277 0.579 rs2103938 chr10:38493998 T/G cg04469686 chr1:162760199 HSD17B7 -0.39 -6.05 -0.31 3.87e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1790761 0.667 rs598811 chr11:67311676 C/T cg21734168 chr11:67353974 GSTP1 -0.27 -6.68 -0.34 9.94e-11 Mean corpuscular volume; LIHC trans rs3760776 0.522 rs78060698 chr19:5832773 G/A cg16574191 chr19:14063234 PODNL1;DCAF15 -0.83 -6.49 -0.33 2.94e-10 N-glycan levels;Tumor biomarkers;Vitamin B12 levels; LIHC trans rs1005277 0.540 rs11011351 chr10:38030525 A/G cg27523141 chr10:43048294 ZNF37B 0.4 7.01 0.35 1.26e-11 Extrinsic epigenetic age acceleration; LIHC cis rs3768617 0.528 rs10911240 chr1:183062948 T/C ch.1.3577855R chr1:183094577 LAMC1 0.63 10.94 0.51 4.35e-24 Fuchs's corneal dystrophy; LIHC cis rs6963495 0.818 rs6973263 chr7:105170293 A/G cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs1691799 0.899 rs1168351 chr12:66752505 A/G cg16791601 chr12:66731901 HELB -0.55 -13.29 -0.58 8.94e-33 White blood cell count (basophil); LIHC cis rs2153535 0.584 rs9502723 chr6:8541504 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.44 0.53 7.27e-26 Motion sickness; LIHC cis rs4820539 1.000 rs5759598 chr22:23480962 T/G cg14186256 chr22:23484241 RTDR1 0.91 18.55 0.71 1.17e-53 Bone mineral density; LIHC cis rs2191566 0.960 rs12232810 chr19:44525122 A/G cg20607764 chr19:44506953 ZNF230 -0.41 -6.7 -0.34 8.85e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs3812831 0.695 rs7998546 chr13:114939914 C/G cg06611532 chr13:114900021 NA 0.4 7.31 0.37 1.93e-12 Schizophrenia; LIHC cis rs11688816 0.569 rs7591708 chr2:63022050 T/C cg17519650 chr2:63277830 OTX1 -0.55 -8.83 -0.43 5.71e-17 Body mass index; LIHC cis rs8084351 0.539 rs11874659 chr18:50588260 T/C cg24270629 chr18:50823537 DCC 0.45 6.95 0.35 1.86e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg05564831 chr3:52568323 NT5DC2 0.36 5.79 0.3 1.61e-8 Bipolar disorder; LIHC cis rs7762018 0.514 rs60671539 chr6:170165981 A/G cg05834625 chr6:170176447 C6orf70 0.42 6.25 0.32 1.2e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs72799341 1.000 rs1458201 chr16:30916129 G/A cg02466173 chr16:30829666 NA -0.43 -6.32 -0.32 8.25e-10 Diastolic blood pressure; LIHC cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg02353165 chr6:42928485 GNMT 0.94 15.14 0.63 5.24e-40 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1371867 0.875 rs28595052 chr8:101327553 G/A cg06636551 chr8:101224915 SPAG1 -0.49 -8.92 -0.43 2.79e-17 Atrioventricular conduction; LIHC cis rs6701037 0.566 rs4344281 chr1:175135376 C/T cg00958927 chr1:175162553 KIAA0040 0.39 6.41 0.33 4.89e-10 Alcohol dependence; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25764190 chr19:44037015 ZNF575 0.38 6.08 0.31 3.29e-9 Cognitive function; LIHC cis rs8027181 0.839 rs7176223 chr15:73077742 T/G cg25632853 chr15:73088954 NA 0.4 6.59 0.34 1.63e-10 Triglyceride levels; LIHC cis rs240764 0.681 rs12209887 chr6:101156806 G/A cg09795085 chr6:101329169 ASCC3 -0.47 -6.78 -0.34 5.15e-11 Neuroticism; LIHC cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg17971929 chr21:40555470 PSMG1 0.83 9.9 0.47 1.78e-20 Cognitive function; LIHC trans rs10506458 0.834 rs73125186 chr12:63373400 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.71 -9.87 -0.47 2.27e-20 Hemostatic factors and hematological phenotypes; LIHC cis rs5769707 0.732 rs135865 chr22:50004829 G/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.74 -0.43 1.09e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg25072359 chr17:41440525 NA 0.38 6.18 0.32 1.82e-9 Menopause (age at onset); LIHC cis rs12922317 0.964 rs8043644 chr16:12077124 G/T cg09319797 chr16:12061715 TNFRSF17 0.4 7.09 0.36 7.68e-12 Schizophrenia; LIHC cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg27170947 chr2:26402098 FAM59B 0.66 8.23 0.41 3.92e-15 Gut microbiome composition (summer); LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.15 -0.32 2.15e-9 Total body bone mineral density; LIHC cis rs1865760 0.929 rs1436307 chr6:25939723 C/T cg03517284 chr6:25882590 NA -0.44 -6.65 -0.34 1.17e-10 Height; LIHC cis rs12477438 0.520 rs6741773 chr2:99738962 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.45 0.64 3.26e-41 Chronic sinus infection; LIHC cis rs2073300 0.609 rs6137929 chr20:23376357 G/A cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17428076 0.793 rs12622772 chr2:172625737 T/C cg13550731 chr2:172543902 DYNC1I2 0.39 6.3 0.32 9.23e-10 Myopia; LIHC cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg18279126 chr7:2041391 MAD1L1 0.36 5.89 0.3 9.28e-9 Bipolar disorder and schizophrenia; LIHC trans rs4290604 0.748 rs10754942 chr2:238075187 T/C cg15676719 chr1:167598521 RCSD1 -0.46 -6.19 -0.32 1.77e-9 Asthma; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03383661 chr6:42714115 TBCC 0.45 6.59 0.34 1.71e-10 Longevity; LIHC cis rs11958404 0.932 rs112993559 chr5:157414712 A/C cg05962755 chr5:157440814 NA 0.96 10.52 0.49 1.28e-22 IgG glycosylation; LIHC cis rs4319547 0.695 rs10744211 chr12:122931820 A/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.22 -0.36 3.39e-12 Body mass index; LIHC trans rs4650994 0.525 rs17361286 chr1:178521916 C/G cg05059571 chr16:84539110 KIAA1609 -0.45 -7.52 -0.38 4.85e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg25364880 chr3:44379878 C3orf23 0.44 6.22 0.32 1.47e-9 Depressive symptoms; LIHC cis rs9381040 1.000 rs9381040 chr6:41154650 C/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.39 -0.33 5.58e-10 Alzheimer's disease (late onset); LIHC cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.36 0.45 1.13e-18 Bipolar disorder; LIHC cis rs9296404 1 rs9296404 chr6:42925803 T/C cg02359409 chr6:42947317 PEX6 -0.48 -6.78 -0.34 5.4e-11 Plasma homocysteine levels (post-methionine load test); LIHC cis rs12478296 0.681 rs73007114 chr2:242984903 T/C cg18898632 chr2:242989856 NA -0.72 -8.92 -0.43 2.84e-17 Obesity-related traits; LIHC cis rs116248771 0.739 rs4680455 chr3:158384883 C/A cg16708174 chr3:158430962 RARRES1 0.48 6.4 0.33 5.08e-10 diarrhoeal disease at age 2; LIHC cis rs561341 0.710 rs9900031 chr17:30199537 T/C cg13647721 chr17:30228624 UTP6 -0.71 -6.42 -0.33 4.53e-10 Hip circumference adjusted for BMI; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14803350 chr5:159545855 PWWP2A -0.32 -6.06 -0.31 3.69e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs10751667 0.666 rs7396473 chr11:966181 T/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs17756712 0.666 rs9378442 chr6:633631 T/G cg14374089 chr6:596013 EXOC2 0.4 5.71 0.3 2.42e-8 Vertical cup-disc ratio; LIHC cis rs2346177 0.580 rs1530628 chr2:46670941 A/G cg02822958 chr2:46747628 ATP6V1E2 0.32 5.97 0.31 5.94e-9 HDL cholesterol; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg06143244 chr16:22435202 RRN3P3 -0.38 -6.12 -0.31 2.61e-9 Calcium levels; LIHC cis rs4665809 1.000 rs4665298 chr2:26256378 G/A cg27170947 chr2:26402098 FAM59B -0.66 -8.21 -0.41 4.48e-15 Gut microbiome composition (summer); LIHC cis rs703842 0.616 rs870392 chr12:58219173 C/A cg04478727 chr12:58166393 METTL1;FAM119B 0.72 10.11 0.48 3.49e-21 Multiple sclerosis; LIHC trans rs3783890 1.000 rs12894309 chr14:93783067 A/T cg02802420 chr16:69363236 PDF;COG8 0.31 6.06 0.31 3.53e-9 Body mass index; LIHC cis rs9868809 0.881 rs13076269 chr3:48675925 T/C cg07636037 chr3:49044803 WDR6 -0.55 -6.19 -0.32 1.77e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs6433857 0.657 rs6756509 chr2:181500273 T/C cg23363182 chr2:181467187 NA -0.36 -5.84 -0.3 1.2e-8 Body mass index; LIHC cis rs11190604 1.000 rs2495752 chr10:102326115 T/C cg07080220 chr10:102295463 HIF1AN 0.53 7.14 0.36 5.47e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs11148252 0.553 rs7999849 chr13:53249414 A/G cg00495681 chr13:53174319 NA 0.67 12.06 0.55 3.72e-28 Lewy body disease; LIHC cis rs6598955 0.694 rs6659387 chr1:26634307 G/A cg04990556 chr1:26633338 UBXN11 -0.61 -9.83 -0.47 3.08e-20 Obesity-related traits; LIHC cis rs9303401 0.659 rs7210432 chr17:56668170 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.29 0.55 5.1e-29 Cognitive test performance; LIHC cis rs763121 0.853 rs138713 chr22:39142615 T/C cg14440974 chr22:39074834 NA -0.39 -6.33 -0.32 7.62e-10 Menopause (age at onset); LIHC cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg19318889 chr4:1322082 MAEA 0.51 8.33 0.41 1.96e-15 Obesity-related traits; LIHC cis rs17384381 1.000 rs12118950 chr1:85864519 T/C cg16011679 chr1:85725395 C1orf52 0.83 8.63 0.42 2.35e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs11711311 1.000 rs10212375 chr3:113471336 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.44 8.47 0.42 7.11e-16 IgG glycosylation; LIHC cis rs8060686 0.516 rs9938020 chr16:68251784 C/G cg05110241 chr16:68378359 PRMT7 -0.51 -6.09 -0.31 3.12e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.42 -5.97 -0.31 5.87e-9 Longevity; LIHC trans rs7613875 0.620 rs7634441 chr3:50071677 G/A cg21659725 chr3:3221576 CRBN -0.55 -8.19 -0.4 5.28e-15 Body mass index; LIHC cis rs921968 0.643 rs2556385 chr2:219532905 G/A cg17980119 chr2:219472607 PLCD4 -0.34 -5.75 -0.3 2e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs17639215 0.550 rs4851003 chr2:102909277 T/C cg09003973 chr2:102972529 NA 0.59 5.84 0.3 1.21e-8 Serum protein levels (sST2); LIHC cis rs12472274 0.617 rs7568705 chr2:239081808 C/T cg17459225 chr2:239074497 NA 0.66 10.63 0.5 5.39e-23 Phospholipid levels (plasma); LIHC cis rs12477438 0.520 rs6717729 chr2:99756941 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 13.97 0.6 2.07e-35 Chronic sinus infection; LIHC cis rs9640161 0.659 rs7806429 chr7:150013393 A/G cg17279839 chr7:150038598 RARRES2 0.47 9.87 0.47 2.21e-20 Blood protein levels;Circulating chemerin levels; LIHC cis rs11628318 0.614 rs7143783 chr14:103128751 A/G cg01864069 chr14:103024347 NA 0.45 6.98 0.35 1.51e-11 Platelet count; LIHC cis rs9486719 1.000 rs3906199 chr6:97049899 C/A cg06623918 chr6:96969491 KIAA0776 -0.66 -6.64 -0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs1559088 0.573 rs1270591 chr19:33622942 C/T cg17764715 chr19:33622953 WDR88 -0.6 -8.67 -0.42 1.8e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg15784997 chr19:3196307 NCLN 0.4 6.13 0.31 2.49e-9 Bilirubin levels; LIHC cis rs1005277 0.505 rs10827836 chr10:38215441 A/G cg25427524 chr10:38739819 LOC399744 0.65 12.52 0.56 7.48e-30 Extrinsic epigenetic age acceleration; LIHC cis rs644799 0.930 rs3802764 chr11:95514599 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 10.01 0.48 7.51e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6598163 0.712 rs10751695 chr12:132291061 A/C cg02426739 chr12:132285352 NA 0.35 5.87 0.3 1.01e-8 Migraine; LIHC cis rs903552 1.000 rs12904206 chr15:102006294 C/T cg00659931 chr15:102010125 PCSK6 -0.45 -6.11 -0.31 2.79e-9 Diabetic kidney disease; LIHC cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg22442454 chr1:209979470 IRF6 0.39 5.84 0.3 1.21e-8 Cleft lip with or without cleft palate; LIHC cis rs3862030 0.839 rs2281880 chr10:104269217 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.6 -0.38 2.89e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs908922 0.676 rs1538082 chr1:152517304 A/G cg20991723 chr1:152506922 NA 0.49 8.32 0.41 2.12e-15 Hair morphology; LIHC cis rs4819852 0.958 rs2238786 chr22:19975444 A/G cg07821417 chr22:19972146 ARVCF 0.46 6.61 0.34 1.48e-10 Pulse pressure; LIHC cis rs12682352 0.715 rs332039 chr8:8723651 C/G cg06636001 chr8:8085503 FLJ10661 0.42 6.36 0.33 6.54e-10 Neuroticism; LIHC trans rs7618501 0.602 rs10049087 chr3:50123417 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.59 -9.46 -0.46 5.02e-19 Intelligence (multi-trait analysis); LIHC cis rs6665290 0.669 rs3795446 chr1:227180981 C/T cg10327440 chr1:227177885 CDC42BPA 1.09 22.73 0.78 2.47e-70 Myeloid white cell count; LIHC cis rs910316 0.737 rs398896 chr14:75482827 C/A cg08847533 chr14:75593920 NEK9 -0.87 -17.99 -0.7 2.11e-51 Height; LIHC cis rs9640161 0.659 rs77354576 chr7:150013300 A/C cg17279839 chr7:150038598 RARRES2 0.48 10.04 0.48 5.91e-21 Blood protein levels;Circulating chemerin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26326168 chr12:133405726 GOLGA3 0.49 6.57 0.33 1.86e-10 Lung function (FEV1/FVC); LIHC cis rs1552244 0.882 rs17081288 chr3:10042113 A/G cg08888203 chr3:10149979 C3orf24 0.47 6.0 0.31 4.97e-9 Alzheimer's disease; LIHC trans rs916888 0.773 rs199443 chr17:44819565 C/T cg13957321 chr17:43675089 NA 0.5 7.97 0.4 2.39e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7903847 0.642 rs11189178 chr10:99143272 T/G cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1046896 1.000 rs1046917 chr17:80685655 A/G cg02711726 chr17:80685570 FN3KRP 0.58 11.69 0.53 8.52e-27 Glycated hemoglobin levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08808811 chr3:184079573 CLCN2 -0.44 -6.7 -0.34 8.72e-11 Systolic blood pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24865406 chr1:230203041 GALNT2 0.39 6.11 0.31 2.67e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4808199 0.947 rs2163804 chr19:19575965 G/A cg03709012 chr19:19516395 GATAD2A 1.09 19.63 0.73 5.64e-58 Nonalcoholic fatty liver disease; LIHC cis rs2952156 0.920 rs2934953 chr17:37832315 T/A cg00129232 chr17:37814104 STARD3 -0.52 -9.49 -0.46 3.99e-19 Asthma; LIHC cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg06238570 chr21:40685208 BRWD1 0.57 6.51 0.33 2.65e-10 Cognitive function; LIHC cis rs7927771 0.524 rs7942074 chr11:47720509 T/C cg20307385 chr11:47447363 PSMC3 0.76 11.44 0.53 6.77e-26 Subjective well-being; LIHC cis rs992157 0.710 rs13026485 chr2:219057984 C/T cg00012203 chr2:219082015 ARPC2 -0.9 -15.61 -0.64 7.66e-42 Colorectal cancer; LIHC cis rs4908768 0.911 rs12121933 chr1:8777081 A/T cg20416874 chr1:8611966 RERE 0.53 8.09 0.4 1.06e-14 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg00081347 chr17:78188837 SGSH 0.47 6.35 0.32 6.81e-10 Hepatitis; LIHC cis rs240764 0.817 rs239245 chr6:101090377 C/A cg09795085 chr6:101329169 ASCC3 0.53 7.48 0.37 6.49e-13 Neuroticism; LIHC cis rs875971 0.964 rs60193905 chr7:65971260 A/G cg18876405 chr7:65276391 NA 0.36 6.48 0.33 3.21e-10 Aortic root size; LIHC cis rs7572733 0.576 rs6734781 chr2:198759973 G/A cg00792783 chr2:198669748 PLCL1 0.48 7.11 0.36 7.02e-12 Dermatomyositis; LIHC trans rs9929218 0.520 rs1078621 chr16:68778996 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.87 18.21 0.7 2.91e-52 Colorectal cancer; LIHC trans rs1005277 0.579 rs116912400 chr10:38479207 G/T cg17830980 chr10:43048298 ZNF37B -0.52 -10.18 -0.48 2e-21 Extrinsic epigenetic age acceleration; LIHC cis rs2279817 0.863 rs6679957 chr1:18011361 T/G cg21791023 chr1:18019539 ARHGEF10L -0.64 -7.48 -0.37 6.38e-13 Neuroticism; LIHC cis rs9372253 1.000 rs9372253 chr6:110716136 C/T cg01119278 chr6:110721349 DDO -0.31 -6.53 -0.33 2.32e-10 Platelet distribution width; LIHC cis rs7512552 0.809 rs9436108 chr1:150360930 A/G cg15654264 chr1:150340011 RPRD2 0.68 11.27 0.52 2.96e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs67981189 0.593 rs221924 chr14:71580778 G/A cg15816911 chr14:71606274 NA -0.43 -6.78 -0.34 5.26e-11 Schizophrenia; LIHC cis rs4803468 0.967 rs67047091 chr19:41938684 C/T cg14132834 chr19:41945861 ATP5SL 0.45 6.59 0.34 1.67e-10 Height; LIHC cis rs7618501 0.602 rs2526743 chr3:50115245 G/A cg21467203 chr3:49911342 NA 0.44 7.76 0.39 1.01e-13 Intelligence (multi-trait analysis); LIHC cis rs3015497 0.789 rs3015498 chr14:51112824 T/C cg09863266 chr14:51125203 SAV1 -0.43 -7.0 -0.35 1.37e-11 Mean platelet volume; LIHC cis rs7618501 0.573 rs2624824 chr3:50088266 T/C cg21467203 chr3:49911342 NA 0.42 7.47 0.37 6.73e-13 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.536 rs4793227 chr17:41412250 A/C cg23758822 chr17:41437982 NA 0.91 16.81 0.67 1.25e-46 Menopause (age at onset); LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg01420254 chr6:26195488 NA 0.51 5.77 0.3 1.77e-8 Gout;Renal underexcretion gout; LIHC cis rs67478160 0.572 rs8015603 chr14:104293678 C/G cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.08 -0.36 8.23e-12 Schizophrenia; LIHC trans rs561341 1.000 rs576985 chr17:30323323 C/T cg20587970 chr11:113659929 NA -1.39 -11.8 -0.54 3.55e-27 Hip circumference adjusted for BMI; LIHC cis rs10489202 0.632 rs275143 chr1:168056724 A/G cg24449463 chr1:168025552 DCAF6 -0.64 -9.8 -0.47 3.94e-20 Schizophrenia; LIHC cis rs9297145 0.958 rs11975761 chr7:98766688 G/A cg05967295 chr7:98741636 SMURF1 -0.71 -11.34 -0.52 1.59e-25 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs7618501 0.933 rs3811695 chr3:49761613 C/T cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.81 0.3 1.46e-8 Bipolar disorder; LIHC cis rs798554 0.797 rs798487 chr7:2802943 G/A cg04166393 chr7:2884313 GNA12 0.43 6.0 0.31 5.06e-9 Height; LIHC cis rs8141529 0.732 rs5752798 chr22:29181868 A/G cg15103426 chr22:29168792 CCDC117 0.67 11.68 0.53 9.47e-27 Lymphocyte counts; LIHC cis rs904251 0.523 rs9366935 chr6:37480404 C/T cg08126542 chr6:37504118 NA -0.37 -6.33 -0.32 7.78e-10 Cognitive performance; LIHC cis rs1957429 0.808 rs4902327 chr14:65344803 C/T cg23373153 chr14:65346875 NA 0.77 10.5 0.49 1.54e-22 Pediatric areal bone mineral density (radius); LIHC cis rs909002 0.772 rs7525618 chr1:32073766 C/T cg13919466 chr1:32135498 COL16A1 -0.34 -6.33 -0.32 7.68e-10 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs2832191 0.720 rs2832200 chr21:30499165 G/A cg08807101 chr21:30365312 RNF160 -0.57 -8.9 -0.43 3.44e-17 Dental caries; LIHC cis rs7131987 0.650 rs7957339 chr12:29456495 T/C cg05697976 chr12:29376483 FAR2 0.29 6.0 0.31 4.96e-9 QT interval; LIHC cis rs7572733 0.515 rs1401096 chr2:198823828 A/G cg10820045 chr2:198174542 NA 0.48 7.23 0.36 3.2e-12 Dermatomyositis; LIHC cis rs4563143 0.663 rs2218396 chr19:29236392 C/T cg12756686 chr19:29218302 NA 0.39 6.65 0.34 1.14e-10 Methadone dose in opioid dependence; LIHC cis rs7395581 0.877 rs7127907 chr11:47324472 A/C cg26139080 chr11:47293733 MADD -0.51 -8.65 -0.42 2.02e-16 HDL cholesterol; LIHC cis rs908922 0.676 rs11205033 chr1:152527966 C/A cg20991723 chr1:152506922 NA 0.57 9.99 0.48 8.48e-21 Hair morphology; LIHC cis rs6918586 0.658 rs198840 chr6:26112164 T/G cg18357526 chr6:26021779 HIST1H4A -0.56 -8.22 -0.41 4.13e-15 Schizophrenia; LIHC cis rs7937682 0.889 rs542424 chr11:111477698 T/C cg09085632 chr11:111637200 PPP2R1B -0.92 -11.29 -0.52 2.52e-25 Primary sclerosing cholangitis; LIHC cis rs1577917 0.771 rs2842608 chr6:86295858 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.75 -0.39 1.03e-13 Response to antipsychotic treatment; LIHC cis rs6547741 0.935 rs6749426 chr2:27847606 T/C cg27432699 chr2:27873401 GPN1 0.78 12.74 0.57 1.12e-30 Oral cavity cancer; LIHC cis rs67460515 0.563 rs16831886 chr3:160799830 A/C cg17135325 chr3:160939158 NMD3 0.54 7.27 0.37 2.54e-12 Parkinson's disease; LIHC trans rs2211698 0.881 rs75650525 chr21:35830233 C/G cg18044562 chr7:50468399 IKZF1 0.52 7.57 0.38 3.46e-13 Cancer; LIHC cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.735 rs910824 chr1:231498773 C/G cg06096015 chr1:231504339 EGLN1 0.51 9.46 0.46 5.03e-19 Hemoglobin concentration; LIHC cis rs2439831 0.681 rs526450 chr15:43599325 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.74 11.06 0.51 1.62e-24 Lung cancer in ever smokers; LIHC cis rs4474465 1.000 rs11237495 chr11:78155090 A/G cg27205649 chr11:78285834 NARS2 -0.38 -5.72 -0.3 2.29e-8 Alzheimer's disease (survival time); LIHC cis rs9611565 0.649 rs9623450 chr22:42175231 G/A cg06634786 chr22:41940651 POLR3H 0.54 5.8 0.3 1.47e-8 Vitiligo; LIHC cis rs7412746 0.658 rs3843843 chr1:150918084 C/T cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs6088580 0.634 rs11700221 chr20:32940320 T/C cg08999081 chr20:33150536 PIGU -0.66 -13.3 -0.58 7.83e-33 Glomerular filtration rate (creatinine); LIHC cis rs9467773 1.000 rs1884946 chr6:26545308 C/G cg11502198 chr6:26597334 ABT1 0.4 5.83 0.3 1.26e-8 Intelligence (multi-trait analysis); LIHC cis rs60871478 1.000 rs62432252 chr7:802886 C/G cg04727924 chr7:799746 HEATR2 -0.59 -8.7 -0.43 1.4e-16 Cerebrospinal P-tau181p levels; LIHC cis rs16912285 0.688 rs7128680 chr11:24338796 C/T ch.11.24196551F chr11:24239977 NA 0.72 8.27 0.41 3.09e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs600806 0.854 rs10745353 chr1:109877506 A/G cg23091122 chr1:110024289 SYPL2 -0.45 -6.0 -0.31 4.98e-9 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg03264133 chr6:25882463 NA -0.63 -8.94 -0.44 2.56e-17 Blood metabolite levels; LIHC cis rs2153535 0.601 rs9502715 chr6:8455709 C/T cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs244293 0.931 rs244351 chr17:53195566 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.51 -0.38 5.37e-13 Menarche (age at onset); LIHC cis rs4925386 0.840 rs6143034 chr20:60920545 T/C cg06026331 chr20:60912101 LAMA5 0.62 9.31 0.45 1.55e-18 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs9309473 0.950 rs13431529 chr2:73876041 G/C cg20560298 chr2:73613845 ALMS1 -0.54 -6.25 -0.32 1.23e-9 Metabolite levels; LIHC trans rs875971 0.545 rs1547529 chr7:65723846 T/C cg26939375 chr7:64535504 NA 0.41 6.52 0.33 2.47e-10 Aortic root size; LIHC cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg17554472 chr22:41940697 POLR3H 0.55 6.23 0.32 1.37e-9 Vitiligo; LIHC cis rs2180341 0.961 rs3798857 chr6:127659473 A/T cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs9918079 0.560 rs4270584 chr4:15600799 A/G cg05003411 chr4:15428768 C1QTNF7 0.32 5.93 0.31 7.38e-9 Obesity-related traits; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.34 0.61 7.33e-37 Prudent dietary pattern; LIHC cis rs4803468 1.000 rs284652 chr19:41928652 C/T cg14132834 chr19:41945861 ATP5SL -0.46 -6.78 -0.34 5.21e-11 Height; LIHC cis rs12908161 0.959 rs12906348 chr15:85329421 A/C cg17507749 chr15:85114479 UBE2QP1 0.6 6.72 0.34 7.82e-11 Schizophrenia; LIHC cis rs72627509 0.638 rs1608165 chr4:57894717 G/C cg16868167 chr4:57843880 C4orf14;POLR2B -0.58 -8.49 -0.42 6.53e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs3820068 0.705 rs4646085 chr1:15825411 A/T cg17385448 chr1:15911702 AGMAT 0.37 6.27 0.32 1.08e-9 Systolic blood pressure; LIHC cis rs34172651 0.876 rs11074653 chr16:24795959 C/T cg04756594 chr16:24857601 SLC5A11 0.46 7.16 0.36 4.92e-12 Intelligence (multi-trait analysis); LIHC cis rs116095464 0.619 rs2303741 chr5:218356 T/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs34779708 0.966 rs12257770 chr10:35517234 A/G cg03585969 chr10:35415529 CREM 0.84 12.75 0.57 9.71e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10751667 0.666 rs10902235 chr11:938892 T/C cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.56e-13 Alzheimer's disease (late onset); LIHC cis rs12611088 0.541 rs2682579 chr19:44012609 T/C cg13740135 chr19:44006432 PHLDB3 -0.42 -6.27 -0.32 1.12e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs11673344 0.797 rs3745768 chr19:37488809 A/G cg27390819 chr19:37464633 NA -0.5 -6.05 -0.31 3.82e-9 Obesity-related traits; LIHC cis rs4788570 0.584 rs11862723 chr16:71704222 T/C cg06353428 chr16:71660113 MARVELD3 1.39 14.48 0.62 2.14e-37 Intelligence (multi-trait analysis); LIHC cis rs6933660 0.721 rs2128945 chr6:151767907 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.56 -8.57 -0.42 3.71e-16 Menarche (age at onset); LIHC cis rs317689 0.819 rs317685 chr12:69715457 A/G cg14784868 chr12:69753453 YEATS4 -0.58 -8.45 -0.42 8.7e-16 Response to diuretic therapy; LIHC trans rs11098499 0.605 rs6833140 chr4:120266822 G/A cg25214090 chr10:38739885 LOC399744 0.44 7.16 0.36 5.09e-12 Corneal astigmatism; LIHC cis rs1707322 0.656 rs3014210 chr1:46066608 A/G cg24296786 chr1:45957014 TESK2 0.4 5.76 0.3 1.88e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11690935 0.921 rs6710698 chr2:172596078 G/C cg13550731 chr2:172543902 DYNC1I2 -0.95 -19.26 -0.72 1.68e-56 Schizophrenia; LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg23131131 chr22:24373011 LOC391322 -0.6 -8.53 -0.42 4.96e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12594515 1.000 rs8038320 chr15:45990267 G/C cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs4803468 1.000 rs10413735 chr19:41921071 C/T cg14132834 chr19:41945861 ATP5SL -0.44 -6.52 -0.33 2.5e-10 Height; LIHC cis rs7131987 0.650 rs6487808 chr12:29463359 C/T cg05697976 chr12:29376483 FAR2 -0.29 -6.01 -0.31 4.62e-9 QT interval; LIHC cis rs3008870 0.917 rs12044492 chr1:67461667 T/C cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC trans rs7395662 0.534 rs12418219 chr11:48988091 G/T cg15704280 chr7:45808275 SEPT13 -0.5 -7.44 -0.37 8.48e-13 HDL cholesterol; LIHC cis rs1568889 1.000 rs35697240 chr11:28287342 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.96 0.35 1.7e-11 Bipolar disorder; LIHC trans rs1728785 0.818 rs11648503 chr16:68598938 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.48 0.33 3.26e-10 Ulcerative colitis; LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg21280719 chr6:42927975 GNMT -0.32 -7.23 -0.36 3.17e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2236918 1.000 rs1635512 chr1:242024500 A/G cg17736920 chr1:242011382 EXO1 -0.59 -9.11 -0.44 6.98e-18 Menopause (age at onset); LIHC cis rs1862618 0.620 rs2591967 chr5:56233551 C/G cg24531977 chr5:56204891 C5orf35 0.54 7.84 0.39 5.6e-14 Initial pursuit acceleration; LIHC cis rs4665809 1.000 rs6546744 chr2:26302161 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -9.02 -0.44 1.34e-17 Gut microbiome composition (summer); LIHC cis rs2180341 0.920 rs6916990 chr6:127698759 G/A cg27446573 chr6:127587934 RNF146 1.04 16.21 0.66 2.92e-44 Breast cancer; LIHC cis rs4629710 0.592 rs11154622 chr6:131547578 C/T cg12606694 chr6:131520996 AKAP7 0.63 7.35 0.37 1.47e-12 Multiple myeloma (IgH translocation); LIHC cis rs11122272 0.603 rs2998427 chr1:231528112 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.59 -0.5 7.44e-23 Hemoglobin concentration; LIHC cis rs6732160 0.549 rs6744529 chr2:73480869 A/G cg24220031 chr2:73402428 NA -0.27 -5.79 -0.3 1.63e-8 Intelligence (multi-trait analysis); LIHC cis rs7184046 0.797 rs13737 chr15:75932129 G/T cg25839482 chr15:75931953 IMP3 0.39 5.72 0.3 2.36e-8 Height; LIHC cis rs7715806 0.500 rs77544433 chr5:75001025 C/A cg19683494 chr5:74908142 NA 0.56 6.67 0.34 1.05e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg11965913 chr1:205819406 PM20D1 0.76 11.04 0.51 1.85e-24 Menarche (age at onset); LIHC cis rs904251 0.861 rs1776456 chr6:37484698 C/G cg08126542 chr6:37504118 NA -0.37 -6.04 -0.31 3.99e-9 Cognitive performance; LIHC cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg18867708 chr6:26865862 GUSBL1 -0.51 -7.74 -0.39 1.12e-13 Schizophrenia; LIHC cis rs6442522 0.733 rs4143273 chr3:15501808 C/T cg16303742 chr3:15540471 COLQ -0.45 -7.52 -0.38 4.71e-13 Uric acid levels; LIHC cis rs1005277 0.579 rs176880 chr10:38401417 C/G cg03665457 chr10:38645376 HSD17B7P2 0.4 5.95 0.31 6.46e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7487075 0.930 rs4076248 chr12:46833605 C/T cg11331445 chr12:47219877 SLC38A4 0.28 5.97 0.31 5.93e-9 Itch intensity from mosquito bite; LIHC cis rs7044106 0.762 rs4142158 chr9:123410819 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.25 0.52 3.29e-25 Hip circumference adjusted for BMI; LIHC cis rs60871478 1.000 rs67721251 chr7:825114 T/C cg27478167 chr7:817139 HEATR2 -0.4 -5.77 -0.3 1.74e-8 Cerebrospinal P-tau181p levels; LIHC cis rs4908768 0.871 rs11121221 chr1:8767529 A/G cg25722041 chr1:8623473 RERE 0.39 5.74 0.3 2.04e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14477263 chr1:1168550 SDF4;B3GALT6 0.43 6.37 0.33 6.18e-10 Longevity; LIHC cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg12292205 chr6:26970375 C6orf41 0.35 5.85 0.3 1.14e-8 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02668984 chr17:48172022 PDK2 0.48 7.43 0.37 8.66e-13 Pancreatic cancer; LIHC cis rs9916302 0.904 rs4794813 chr17:37670994 A/T cg07936489 chr17:37558343 FBXL20 -0.81 -13.0 -0.58 1.14e-31 Glomerular filtration rate (creatinine); LIHC cis rs9457247 1.000 rs429083 chr6:167383972 T/C cg12798992 chr6:167411361 FGFR1OP 0.59 9.73 0.47 6.7e-20 Crohn's disease; LIHC cis rs9513627 1.000 rs7322368 chr13:100213990 T/C cg25919922 chr13:100150906 NA 0.76 6.67 0.34 1.02e-10 Obesity-related traits; LIHC cis rs7772486 0.754 rs6921073 chr6:146144377 G/A cg23711669 chr6:146136114 FBXO30 0.63 11.35 0.52 1.44e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs3741151 1.000 rs112840535 chr11:73066771 G/A cg17517138 chr11:73019481 ARHGEF17 0.93 6.79 0.34 4.98e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg08280861 chr8:58055591 NA 0.56 6.26 0.32 1.19e-9 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.647 rs12905181 chr15:77098431 A/G cg03037974 chr15:76606532 NA -0.61 -10.21 -0.48 1.55e-21 Blood metabolite levels; LIHC cis rs6748734 0.857 rs10933638 chr2:241794655 G/A cg09990169 chr2:241835740 C2orf54 -0.65 -10.32 -0.49 6.65e-22 Urinary metabolites; LIHC cis rs6456156 0.586 rs7742305 chr6:167485723 C/T cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.07e-9 Primary biliary cholangitis; LIHC cis rs74544699 1.000 rs79981249 chr4:74784164 T/C cg16072462 chr4:74847758 PF4 0.6 6.14 0.32 2.27e-9 Growth-regulated protein alpha levels; LIHC cis rs611744 0.967 rs639059 chr8:109236119 G/A cg21045802 chr8:109455806 TTC35 0.51 8.81 0.43 6.6e-17 Dupuytren's disease; LIHC cis rs6500602 0.702 rs2058812 chr16:4524443 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.79 0.39 7.8500000000000006e-14 Schizophrenia; LIHC cis rs8062405 0.755 rs56209193 chr16:28585636 C/T cg07382826 chr16:28625726 SULT1A1 0.51 7.92 0.39 3.44e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2629540 0.889 rs4962699 chr10:126477209 A/G cg08799069 chr10:126477246 METTL10 -0.55 -9.23 -0.45 2.92e-18 Cocaine dependence; LIHC cis rs11608355 0.515 rs11610558 chr12:109925865 C/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs748404 0.660 rs690012 chr15:43719755 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.92 0.39 3.41e-14 Lung cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20236831 chr1:1259679 GLTPD1;CPSF3L -0.55 -6.42 -0.33 4.47e-10 Systolic blood pressure; LIHC cis rs8078723 1.000 rs4795416 chr17:38158133 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.58 -9.27 -0.45 2.17e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs244293 0.899 rs244355 chr17:53194085 A/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.47 -0.37 6.93e-13 Menarche (age at onset); LIHC cis rs1005277 0.579 rs2474567 chr10:38382492 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg06634786 chr22:41940651 POLR3H -0.8 -8.79 -0.43 7.39e-17 Vitiligo; LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg02869306 chr7:64672164 INTS4L1 -0.28 -6.07 -0.31 3.4e-9 Calcium levels; LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg13409248 chr3:40428643 ENTPD3 -0.51 -8.62 -0.42 2.46e-16 Renal cell carcinoma; LIHC cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg06238570 chr21:40685208 BRWD1 0.56 6.79 0.34 4.99e-11 Cognitive function; LIHC cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.19 -0.44 3.99e-18 Bipolar disorder; LIHC cis rs8077889 0.672 rs1230400 chr17:41845451 G/A cg26893861 chr17:41843967 DUSP3 -1.07 -19.71 -0.73 2.65e-58 Triglycerides; LIHC trans rs76648483 0.568 rs1987102 chr15:80265888 T/C cg11476254 chr16:89159666 ACSF3 -0.5 -6.43 -0.33 4.37e-10 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04633058 chr17:48474099 LRRC59 0.41 6.66 0.34 1.07e-10 Cognitive function; LIHC cis rs7772486 0.764 rs2265468 chr6:146218346 A/C cg23711669 chr6:146136114 FBXO30 0.71 12.33 0.55 3.62e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs9640161 0.830 rs35840727 chr7:150063204 A/G cg17279839 chr7:150038598 RARRES2 0.39 7.58 0.38 3.24e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs208520 0.690 rs1563929 chr6:66702108 G/A cg07460842 chr6:66804631 NA 0.74 8.43 0.41 9.88e-16 Exhaled nitric oxide output; LIHC cis rs1023500 0.573 rs133370 chr22:42465260 T/C cg00645731 chr22:42541494 CYP2D7P1 0.39 6.15 0.32 2.18e-9 Schizophrenia; LIHC cis rs58235267 0.564 rs360808 chr2:62927475 T/C cg17519650 chr2:63277830 OTX1 -0.61 -9.93 -0.47 1.38e-20 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs17376456 0.877 rs12374488 chr5:93481407 A/G cg25358565 chr5:93447407 FAM172A 1.12 10.26 0.49 1.06e-21 Diabetic retinopathy; LIHC cis rs4917300 0.586 rs1352949 chr8:143096253 G/C cg25363559 chr8:143086065 NA -0.27 -8.22 -0.41 4.42e-15 Amyotrophic lateral sclerosis; LIHC cis rs1552244 0.882 rs3732966 chr3:10015740 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs3768617 0.706 rs10797801 chr1:182971965 G/T ch.1.3577855R chr1:183094577 LAMC1 0.5 7.93 0.39 3.23e-14 Fuchs's corneal dystrophy; LIHC cis rs34172651 0.917 rs2343606 chr16:24793741 C/T cg00339695 chr16:24857497 SLC5A11 0.54 8.19 0.4 5.43e-15 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.904 rs2303316 chr17:37704217 A/G cg00129232 chr17:37814104 STARD3 -0.42 -6.77 -0.34 5.5e-11 Glomerular filtration rate (creatinine); LIHC cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -14.52 -0.62 1.44e-37 Alzheimer's disease; LIHC cis rs7584330 0.910 rs12465081 chr2:238401784 A/G cg14458575 chr2:238380390 NA 0.36 5.72 0.3 2.29e-8 Prostate cancer; LIHC cis rs7520050 0.902 rs1355642 chr1:46598903 A/G cg03146154 chr1:46216737 IPP -0.35 -5.84 -0.3 1.21e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg21486233 chr12:29375141 FAR2 0.31 6.22 0.32 1.46e-9 QT interval; LIHC cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg06453172 chr10:134556979 INPP5A -0.65 -8.13 -0.4 8.08e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs16958440 0.867 rs12326457 chr18:44678425 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs273218 1.000 rs156437 chr5:53376454 C/T ch.5.1024479R chr5:53302184 ARL15 0.62 10.07 0.48 4.8e-21 Migraine; LIHC cis rs9549367 0.789 rs9549695 chr13:113874814 A/G cg18105134 chr13:113819100 PROZ 0.63 10.63 0.5 5.4e-23 Platelet distribution width; LIHC cis rs7613875 0.600 rs1061474 chr3:50144951 T/C cg05623727 chr3:50126028 RBM5 -0.35 -6.05 -0.31 3.89e-9 Body mass index; LIHC cis rs2303745 0.589 rs1864116 chr19:17393015 C/T cg10664184 chr19:17420304 DDA1 0.45 5.74 0.3 2.12e-8 Systemic lupus erythematosus; LIHC cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg21724239 chr8:58056113 NA 0.49 6.5 0.33 2.77e-10 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.875 rs6909827 chr6:146365738 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.79 0.3 1.63e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2976388 0.556 rs4736300 chr8:143829269 C/T cg24634471 chr8:143751801 JRK -0.41 -5.98 -0.31 5.52e-9 Urinary tract infection frequency; LIHC cis rs4555082 0.957 rs2816628 chr14:105736134 T/G cg10792982 chr14:105748885 BRF1 0.43 6.05 0.31 3.77e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg08048268 chr3:133502702 NA -0.42 -6.27 -0.32 1.07e-9 Iron status biomarkers; LIHC cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg24549020 chr5:56110836 MAP3K1 0.47 6.04 0.31 4.11e-9 Initial pursuit acceleration; LIHC cis rs17253792 0.822 rs12100753 chr14:56042870 G/A cg01858014 chr14:56050164 KTN1 -0.7 -7.18 -0.36 4.46e-12 Putamen volume; LIHC cis rs875971 0.545 rs6950988 chr7:65976415 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 6.91 0.35 2.44e-11 Aortic root size; LIHC cis rs10463316 0.894 rs6579864 chr5:150762181 G/A cg03212797 chr5:150827313 SLC36A1 -0.45 -6.76 -0.34 5.87e-11 Metabolite levels (Pyroglutamine); LIHC cis rs7633770 0.786 rs6442012 chr3:46686346 A/G cg11219411 chr3:46661640 NA 0.44 7.77 0.39 9.04e-14 Coronary artery disease; LIHC cis rs67311347 0.866 rs11712426 chr3:40330322 G/A cg00656387 chr3:40428638 ENTPD3 0.38 5.96 0.31 6.37e-9 Renal cell carcinoma; LIHC cis rs6952808 0.771 rs10269191 chr7:1915731 A/G cg14004847 chr7:1930337 MAD1L1 -0.52 -7.51 -0.38 5.07e-13 Bipolar disorder and schizophrenia; LIHC cis rs7172677 0.696 rs56262544 chr15:75379471 A/G cg09165964 chr15:75287851 SCAMP5 0.48 6.48 0.33 3.28e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11626933 1.000 rs4559843 chr14:90747488 T/C cg04374321 chr14:90722782 PSMC1 0.47 6.5 0.33 2.85e-10 Gut microbiota (bacterial taxa); LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs963731 0.579 rs2373497 chr2:39288098 C/T cg04010122 chr2:39346883 SOS1 -0.57 -5.79 -0.3 1.63e-8 Corticobasal degeneration; LIHC cis rs10911232 0.507 rs7515822 chr1:183037803 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.58 0.5 7.92e-23 Hypertriglyceridemia; LIHC trans rs634534 0.562 rs661335 chr11:65754061 G/A cg17712092 chr4:129076599 LARP1B 0.72 12.51 0.56 8.06e-30 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs10089 1.000 rs2054444 chr5:127493206 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.52 -6.62 -0.34 1.41e-10 Ileal carcinoids; LIHC cis rs898097 0.812 rs56405605 chr17:80843663 T/C cg15369054 chr17:80825471 TBCD 0.43 6.02 0.31 4.55e-9 Breast cancer; LIHC cis rs10791323 0.660 rs2156681 chr11:133731644 G/T cg15485101 chr11:133734466 NA 0.26 6.28 0.32 1.05e-9 Childhood ear infection; LIHC cis rs4665809 1.000 rs4665817 chr2:26305167 G/A cg04944784 chr2:26401820 FAM59B -0.68 -8.56 -0.42 3.77e-16 Gut microbiome composition (summer); LIHC cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC cis rs75908454 1.000 rs76123929 chr6:169829086 G/T cg19338460 chr6:170058176 WDR27 -0.86 -7.77 -0.39 9.33e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs2235642 0.891 rs2281231 chr16:1601879 A/G cg03034668 chr16:1723424 CRAMP1L -0.38 -6.8 -0.35 4.65e-11 Coronary artery disease; LIHC cis rs4908768 0.906 rs10492965 chr1:8598127 G/A cg20416874 chr1:8611966 RERE 0.58 9.1 0.44 7.41e-18 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs611744 0.647 rs579162 chr8:109254842 A/G cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs7312933 0.612 rs10785334 chr12:42620377 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.53 -7.72 -0.39 1.29e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8064299 0.655 rs12797 chr17:72766993 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.65 10.13 0.48 2.86e-21 Monocyte count; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.71 -0.3 2.45e-8 Total body bone mineral density; LIHC cis rs11676348 0.904 rs10804264 chr2:218955809 T/C cg00012203 chr2:219082015 ARPC2 -0.52 -6.99 -0.35 1.4e-11 Ulcerative colitis; LIHC cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg21280719 chr6:42927975 GNMT -0.37 -8.05 -0.4 1.36e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1008375 0.932 rs4698629 chr4:17608884 C/G cg02297831 chr4:17616191 MED28 0.43 6.21 0.32 1.57e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg02931644 chr1:25747376 RHCE 0.35 7.63 0.38 2.31e-13 Erythrocyte sedimentation rate; LIHC cis rs9549367 0.789 rs34989271 chr13:113894766 G/A cg00898013 chr13:113819073 PROZ -0.42 -7.35 -0.37 1.46e-12 Platelet distribution width; LIHC cis rs17376456 0.877 rs10073039 chr5:93467709 A/G cg25358565 chr5:93447407 FAM172A 1.12 10.35 0.49 5.17e-22 Diabetic retinopathy; LIHC cis rs2439831 0.850 rs2957637 chr15:43951118 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.2 0.45 3.6e-18 Lung cancer in ever smokers; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.93 0.63 3.67e-39 Prudent dietary pattern; LIHC cis rs6500602 0.702 rs4786493 chr16:4500122 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 6.07 0.31 3.37e-9 Schizophrenia; LIHC cis rs6463523 0.933 rs6974151 chr7:758269 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.96 16.77 0.67 1.82e-46 Subjective well-being; LIHC cis rs311392 0.554 rs311390 chr8:55102401 G/A cg20636351 chr8:55087400 NA -0.34 -7.13 -0.36 6.09e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs875971 0.838 rs2173570 chr7:65762963 T/A cg18876405 chr7:65276391 NA -0.36 -6.58 -0.34 1.73e-10 Aortic root size; LIHC cis rs12765878 1.000 rs35223321 chr10:105646395 C/T cg11005552 chr10:105648138 OBFC1 0.37 5.76 0.3 1.87e-8 Coronary artery disease; LIHC cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.69 0.34 9.33e-11 Bipolar disorder; LIHC cis rs7264396 1.000 rs224409 chr20:34124920 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.77 -0.34 5.74e-11 Total cholesterol levels; LIHC cis rs36051895 0.589 rs7038763 chr9:5076399 T/C cg02405213 chr9:5042618 JAK2 -0.72 -13.11 -0.58 4.34e-32 Pediatric autoimmune diseases; LIHC cis rs2857078 0.654 rs4793083 chr17:42312973 C/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.67 -10.04 -0.48 6.02e-21 Red cell distribution width;Reticulocyte count; LIHC cis rs34779708 0.733 rs7086715 chr10:35541840 A/G cg03585969 chr10:35415529 CREM 0.76 10.96 0.51 3.65e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7771547 0.589 rs6941918 chr6:36514721 T/G cg07856975 chr6:36356162 ETV7 0.38 6.25 0.32 1.22e-9 Platelet distribution width; LIHC trans rs2739330 0.731 rs2000468 chr22:24241611 G/T cg06437703 chr8:37914619 EIF4EBP1 -0.55 -8.37 -0.41 1.5e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8044868 0.530 rs12446480 chr16:72056757 A/G cg01557791 chr16:72042693 DHODH -0.41 -6.88 -0.35 2.88e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs13108904 0.901 rs66987549 chr4:1272617 C/T cg20887711 chr4:1340912 KIAA1530 0.59 9.16 0.44 4.76e-18 Obesity-related traits; LIHC cis rs2370759 1.000 rs16933243 chr10:32615135 T/C cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs12701220 0.655 rs10241018 chr7:1144774 G/C cg00990874 chr7:1149470 C7orf50 -0.7 -9.96 -0.47 1.08e-20 Bronchopulmonary dysplasia; LIHC trans rs72829446 0.530 rs4796421 chr17:7379650 C/T cg08566640 chr11:64091735 NA -0.75 -6.92 -0.35 2.25e-11 Androgen levels; LIHC cis rs881375 0.715 rs7858209 chr9:123645760 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.4 6.04 0.31 4.04e-9 Rheumatoid arthritis; LIHC cis rs12477438 0.520 rs2632283 chr2:99776000 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs7534824 0.625 rs72736234 chr1:101526098 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.74 6.93 0.35 2.06e-11 Refractive astigmatism; LIHC cis rs3806843 1.000 rs1476768 chr5:140173597 G/A cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.65e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs910316 0.789 rs175457 chr14:75584507 C/T cg08847533 chr14:75593920 NEK9 -0.9 -18.61 -0.71 6.58e-54 Height; LIHC cis rs921968 0.643 rs524012 chr2:219433273 T/G cg17980119 chr2:219472607 PLCD4 0.34 5.81 0.3 1.43e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs74544699 1.000 rs116254820 chr4:74804444 G/A cg16072462 chr4:74847758 PF4 0.57 5.86 0.3 1.11e-8 Growth-regulated protein alpha levels; LIHC cis rs3020736 0.500 rs6002597 chr22:42488160 C/A cg04733989 chr22:42467013 NAGA -0.66 -9.37 -0.45 1.01e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs13191362 0.935 rs66962088 chr6:162963891 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.87 0.3 1.04e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7027203 0.828 rs7037960 chr9:96584028 G/A cg14598338 chr9:96623480 NA -0.31 -6.21 -0.32 1.58e-9 DNA methylation (variation); LIHC cis rs1005277 0.579 rs2474594 chr10:38426661 G/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs73001065 0.901 rs73004959 chr19:19711139 C/T cg03709012 chr19:19516395 GATAD2A 0.9 8.04 0.4 1.44e-14 LDL cholesterol; LIHC cis rs1799949 1.000 rs8070085 chr17:41341984 C/T cg25072359 chr17:41440525 NA -0.36 -5.77 -0.3 1.76e-8 Menopause (age at onset); LIHC cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg03264133 chr6:25882463 NA -0.63 -8.85 -0.43 4.88e-17 Blood metabolite levels; LIHC cis rs11588062 0.628 rs11211270 chr1:46838986 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.45 7.04 0.36 1.09e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs908922 0.676 rs4845443 chr1:152507156 C/T cg20991723 chr1:152506922 NA 0.6 10.87 0.51 7.75e-24 Hair morphology; LIHC cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.22e-8 Menopause (age at onset); LIHC cis rs10078 0.559 rs2671891 chr5:456386 A/G cg07599136 chr5:415885 AHRR 0.79 12.86 0.57 3.74e-31 Fat distribution (HIV); LIHC cis rs6121246 0.909 rs1994250 chr20:30287494 A/G cg13852791 chr20:30311386 BCL2L1 0.94 9.63 0.46 1.39e-19 Mean corpuscular hemoglobin; LIHC cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg12310025 chr6:25882481 NA -0.57 -8.36 -0.41 1.61e-15 Blood metabolite levels; LIHC cis rs17685 0.712 rs6954569 chr7:75738885 T/A cg01364799 chr7:75623366 TMEM120A -0.48 -7.2 -0.36 3.79e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs911119 0.913 rs3004145 chr20:23582876 C/G cg16589663 chr20:23618590 CST3 -0.67 -7.23 -0.36 3.23e-12 Chronic kidney disease; LIHC trans rs2228638 1.000 rs12415845 chr10:33472820 T/A cg17012154 chr7:2275030 FTSJ2 0.63 6.06 0.31 3.51e-9 Tetralogy of Fallot; LIHC cis rs2559856 1.000 rs2695282 chr12:102089502 A/G cg12924262 chr12:102091054 CHPT1 -0.52 -8.46 -0.42 7.64e-16 Blood protein levels; LIHC cis rs74233809 1.000 rs78821730 chr10:104684544 G/A cg03493300 chr10:104813866 CNNM2 0.46 6.02 0.31 4.57e-9 Birth weight; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC trans rs1814175 0.615 rs4545557 chr11:50027329 A/C cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs2439831 1.000 rs690316 chr15:43737880 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.64 9.18 0.44 4.23e-18 Lung cancer in ever smokers; LIHC cis rs9916302 0.904 rs2061342 chr17:37405657 T/G cg00129232 chr17:37814104 STARD3 -0.41 -6.54 -0.33 2.22e-10 Glomerular filtration rate (creatinine); LIHC cis rs2370759 1.000 rs16933177 chr10:32565705 G/A cg01819863 chr10:32635814 EPC1 1.12 16.62 0.67 6.91e-46 Sexual dysfunction (female); LIHC cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg11890956 chr21:40555474 PSMG1 1.02 14.54 0.62 1.3e-37 Cognitive function; LIHC cis rs2991971 0.967 rs6661321 chr1:45954599 C/G cg05343316 chr1:45956843 TESK2 -0.42 -6.19 -0.32 1.69e-9 High light scatter reticulocyte count; LIHC cis rs67311347 0.910 rs7617361 chr3:40373259 G/T cg16822855 chr3:40428330 ENTPD3 0.32 5.87 0.3 1.03e-8 Renal cell carcinoma; LIHC cis rs17539620 0.624 rs12665520 chr6:154835273 C/T cg17771515 chr6:154831774 CNKSR3 0.59 6.53 0.33 2.36e-10 Lipoprotein (a) levels; LIHC cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg16325326 chr1:53192061 ZYG11B -0.5 -8.85 -0.43 4.65e-17 Monocyte count; LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs1023500 0.573 rs133382 chr22:42471774 C/T cg15557168 chr22:42548783 NA -0.42 -6.69 -0.34 8.95e-11 Schizophrenia; LIHC cis rs763014 0.966 rs15564 chr16:677854 G/T cg27189623 chr16:705930 WDR90 0.44 7.49 0.38 6.02e-13 Height; LIHC cis rs7481584 0.624 rs369461 chr11:3061992 A/G cg25174290 chr11:3078921 CARS -0.42 -6.26 -0.32 1.13e-9 Calcium levels; LIHC cis rs9388451 0.839 rs11154331 chr6:126111429 A/T cg05901451 chr6:126070800 HEY2 -0.73 -16.51 -0.67 1.98e-45 Brugada syndrome; LIHC cis rs7584330 0.554 rs11892169 chr2:238432809 G/A cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.42e-9 Prostate cancer; LIHC cis rs1030268 0.962 rs12707122 chr7:133517309 A/C cg03336402 chr7:133662267 EXOC4 -0.46 -6.32 -0.32 7.99e-10 Intelligence (multi-trait analysis); LIHC cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg12292205 chr6:26970375 C6orf41 -0.41 -7.05 -0.36 9.67e-12 Schizophrenia; LIHC trans rs11764590 0.813 rs11768212 chr7:1992582 A/C cg11693508 chr17:37793320 STARD3 0.75 7.41 0.37 9.91e-13 Neuroticism; LIHC cis rs751728 1.000 rs4713684 chr6:33766488 T/C cg25922239 chr6:33757077 LEMD2 0.42 7.16 0.36 5.05e-12 Crohn's disease; LIHC cis rs1057239 0.739 rs1014554 chr1:175133626 A/G cg17845761 chr1:175162550 KIAA0040 0.4 6.88 0.35 2.84e-11 Diastolic blood pressure; LIHC cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Bipolar disorder; LIHC cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.03 -10.57 -0.5 8.95e-23 Platelet count; LIHC cis rs9325144 0.555 rs7301258 chr12:38706942 C/T cg26384229 chr12:38710491 ALG10B 0.54 7.79 0.39 8.3e-14 Morning vs. evening chronotype; LIHC cis rs939574 0.512 rs908197 chr2:220144410 G/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.6 7.16 0.36 4.95e-12 Platelet distribution width; LIHC cis rs4319547 0.915 rs3803005 chr12:123110654 T/C cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.52 -0.38 5.01e-13 Body mass index; LIHC cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg12310025 chr6:25882481 NA -0.64 -9.01 -0.44 1.54e-17 Blood metabolite levels; LIHC cis rs7412746 0.611 rs72704679 chr1:150897477 C/T cg18016565 chr1:150552671 MCL1 0.5 9.51 0.46 3.62e-19 Melanoma; LIHC cis rs3020736 0.500 rs7292241 chr22:42492063 G/A cg04733989 chr22:42467013 NAGA -0.66 -9.37 -0.45 1.01e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs4845459 0.967 rs6700158 chr1:152592828 T/G cg20634798 chr1:152595351 LCE3A -0.31 -6.07 -0.31 3.46e-9 Psoriasis; LIHC cis rs7520050 0.931 rs6698247 chr1:46371486 C/T cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.97e-9 Red blood cell count;Reticulocyte count; LIHC cis rs9948 0.529 rs62156222 chr2:97410988 C/A cg01990225 chr2:97406019 LMAN2L -0.81 -6.32 -0.32 8.31e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs2842992 0.830 rs2758313 chr6:160154099 C/G cg11366901 chr6:160182831 ACAT2 0.96 16.18 0.66 4.17e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs798554 0.660 rs2644275 chr7:2854010 G/A cg13628971 chr7:2884303 GNA12 0.42 6.57 0.33 1.93e-10 Height; LIHC cis rs735396 0.770 rs1169315 chr12:121443753 T/G cg02403541 chr12:121454288 C12orf43 0.52 9.14 0.44 5.56e-18 N-glycan levels; LIHC cis rs11792861 0.962 rs3829084 chr9:111801724 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.59 -8.25 -0.41 3.5e-15 Menarche (age at onset); LIHC cis rs875971 1.000 rs6979382 chr7:65886375 C/T cg18252515 chr7:66147081 NA -0.41 -5.76 -0.3 1.86e-8 Aortic root size; LIHC cis rs2239547 0.657 rs4687672 chr3:52880543 G/A cg18404041 chr3:52824283 ITIH1 -0.42 -5.88 -0.3 9.64e-9 Schizophrenia; LIHC cis rs7937682 0.847 rs11213948 chr11:111464401 G/A cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs1005277 0.602 rs2504142 chr10:38383793 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs7772486 0.754 rs702319 chr6:146006117 T/C cg13319975 chr6:146136371 FBXO30 0.46 7.16 0.36 5.09e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs16854884 0.657 rs7642774 chr3:143723272 T/A cg06585982 chr3:143692056 C3orf58 0.55 7.16 0.36 5e-12 Economic and political preferences (feminism/equality); LIHC cis rs7193541 0.673 rs12716769 chr16:74652537 T/C cg01733217 chr16:74700730 RFWD3 0.95 22.19 0.77 3.15e-68 Multiple myeloma; LIHC cis rs13108904 0.901 rs7695691 chr4:1304632 A/G cg13395646 chr4:1353034 KIAA1530 -0.44 -7.01 -0.35 1.32e-11 Obesity-related traits; LIHC cis rs1355223 1.000 rs11607300 chr11:34759319 C/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.27 -0.32 1.08e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7264396 0.635 rs6088971 chr20:34535373 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.75 -0.5 2.07e-23 Total cholesterol levels; LIHC cis rs5753037 0.809 rs17711377 chr22:30212986 C/T cg01021169 chr22:30184971 ASCC2 -0.35 -6.59 -0.34 1.65e-10 Type 1 diabetes; LIHC cis rs2710642 0.888 rs2539985 chr2:63134507 T/A cg17519650 chr2:63277830 OTX1 0.55 8.35 0.41 1.74e-15 LDL cholesterol levels;LDL cholesterol; LIHC cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7172677 0.501 rs8041446 chr15:75394517 C/T cg15902774 chr15:75289873 SCAMP5 0.34 5.96 0.31 6.31e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs875971 0.825 rs1129531 chr7:65619104 C/T cg11764359 chr7:65958608 NA -0.83 -13.95 -0.6 2.63e-35 Aortic root size; LIHC cis rs459571 0.876 rs2520095 chr9:136919568 A/G cg13789015 chr9:136890014 NCRNA00094 0.45 8.28 0.41 2.83e-15 Platelet distribution width; LIHC cis rs2115630 0.818 rs7176522 chr15:85215383 C/G cg12501888 chr15:85177176 SCAND2 -0.51 -7.9 -0.39 3.88e-14 P wave terminal force; LIHC cis rs36051895 0.623 rs17426903 chr9:5203292 A/C cg02405213 chr9:5042618 JAK2 -0.62 -9.82 -0.47 3.14e-20 Pediatric autoimmune diseases; LIHC cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg09222892 chr1:25734099 RHCE -0.45 -8.22 -0.41 4.25e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC cis rs2637030 0.559 rs2636991 chr5:52943067 T/G cg06476337 chr5:52856530 NDUFS4 0.43 6.82 0.35 4.25e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs1914816 1.000 rs2456075 chr15:76555986 C/T cg03037974 chr15:76606532 NA -0.61 -6.36 -0.33 6.48e-10 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs1707322 1.000 rs6677777 chr1:46475836 A/G cg06784218 chr1:46089804 CCDC17 0.38 6.69 0.34 9.02e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2354432 0.607 rs7537483 chr1:146709877 C/G cg25205988 chr1:146714368 CHD1L 0.93 11.04 0.51 1.9e-24 Mitochondrial DNA levels; LIHC cis rs10857712 0.754 rs2297031 chr10:135232654 C/T cg17796960 chr10:135278976 LOC619207 -0.35 -5.77 -0.3 1.78e-8 Systemic lupus erythematosus; LIHC cis rs7520050 0.933 rs4504835 chr1:46455571 G/A cg03146154 chr1:46216737 IPP -0.39 -6.42 -0.33 4.48e-10 Red blood cell count;Reticulocyte count; LIHC cis rs748404 0.631 rs7163288 chr15:43671355 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.55 8.67 0.42 1.75e-16 Lung cancer; LIHC cis rs10504229 0.906 rs2270608 chr8:58194688 T/C cg20607798 chr8:58055168 NA 0.5 5.91 0.3 8.11e-9 Developmental language disorder (linguistic errors); LIHC trans rs4942242 0.663 rs9590779 chr13:44234886 A/G cg19169023 chr15:41853346 TYRO3 0.51 7.29 0.37 2.18e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs4423214 1.000 rs732934 chr11:71186476 G/A cg24826892 chr11:71159390 DHCR7 0.5 6.43 0.33 4.31e-10 Vitamin D levels; LIHC cis rs244293 0.931 rs244349 chr17:53196169 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.5 -0.38 5.39e-13 Menarche (age at onset); LIHC cis rs6963495 0.818 rs115609508 chr7:105163716 C/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs6089584 0.924 rs6142906 chr20:60552554 G/C cg12751644 chr20:60527061 NA -0.37 -6.04 -0.31 3.94e-9 Body mass index; LIHC cis rs919433 0.648 rs3097384 chr2:198278834 T/A cg10820045 chr2:198174542 NA 0.55 8.96 0.44 2.12e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg16132339 chr22:24313637 DDTL;DDT 0.66 11.66 0.53 1.09e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg11644478 chr21:40555479 PSMG1 -0.37 -5.77 -0.3 1.82e-8 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01358551 chr19:47353761 AP2S1 0.45 6.57 0.33 1.88e-10 Cognitive function; LIHC cis rs7927592 0.913 rs7115374 chr11:68300076 G/T cg20283391 chr11:68216788 NA -0.52 -7.8 -0.39 7.74e-14 Total body bone mineral density; LIHC cis rs10504073 0.584 rs62507182 chr8:49942500 C/A cg00325661 chr8:49890786 NA 0.34 7.78 0.39 8.45e-14 Blood metabolite ratios; LIHC cis rs9378688 0.654 rs2450307 chr6:2324639 A/G cg12303981 chr6:2244766 GMDS -0.43 -6.08 -0.31 3.21e-9 Caudate nucleus volume; LIHC cis rs2625529 0.938 rs2742323 chr15:72116778 A/T cg16672083 chr15:72433130 SENP8 0.32 6.05 0.31 3.77e-9 Red blood cell count; LIHC cis rs9814567 0.762 rs13070654 chr3:134219348 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 7.25 0.36 2.87e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9325144 0.600 rs10785621 chr12:38744912 C/T cg26384229 chr12:38710491 ALG10B 0.59 8.21 0.41 4.57e-15 Morning vs. evening chronotype; LIHC trans rs1814175 0.817 rs10839358 chr11:49770972 G/A cg03929089 chr4:120376271 NA -0.9 -18.39 -0.71 5.32e-53 Height; LIHC cis rs7044106 0.791 rs10985008 chr9:123492960 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.59 9.25 0.45 2.56e-18 Hip circumference adjusted for BMI; LIHC cis rs921968 0.565 rs13408427 chr2:219628389 C/T cg02985541 chr2:219472218 PLCD4 -0.36 -6.36 -0.33 6.34e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs4689592 0.503 rs4689064 chr4:7055603 A/G cg26116260 chr4:7069785 GRPEL1 -1.01 -17.63 -0.69 6.12e-50 Monocyte percentage of white cells; LIHC cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg05590025 chr7:65112418 INTS4L2 0.62 6.79 0.34 4.9e-11 Diabetic kidney disease; LIHC trans rs5756813 0.870 rs5756812 chr22:38173113 C/T cg19894588 chr14:64061835 NA 0.7 10.05 0.48 5.4e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg11644478 chr21:40555479 PSMG1 0.78 9.96 0.47 1.06e-20 Cognitive function; LIHC cis rs17125944 0.686 rs1952090 chr14:53342992 A/G cg00686598 chr14:53173677 PSMC6 -0.7 -7.73 -0.39 1.24e-13 Alzheimer's disease (late onset); LIHC cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10751667 0.961 rs7395303 chr11:986221 T/A ch.11.42038R chr11:967971 AP2A2 0.61 11.3 0.52 2.28e-25 Alzheimer's disease (late onset); LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg09177884 chr7:1199841 ZFAND2A -0.44 -6.3 -0.32 9.17e-10 Longevity;Endometriosis; LIHC cis rs3736485 0.868 rs2124592 chr15:51922979 G/A cg08986416 chr15:51914746 DMXL2 -0.45 -6.55 -0.33 2.05e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9733 0.650 rs2048558 chr1:150571730 A/G cg17724175 chr1:150552817 MCL1 -0.37 -7.5 -0.38 5.69e-13 Tonsillectomy; LIHC cis rs3751667 0.506 rs4984718 chr16:974411 T/A cg04357082 chr16:980022 LMF1 0.47 8.22 0.41 4.16e-15 Non-glioblastoma glioma;Glioblastoma;Glioma; LIHC cis rs3091242 0.933 rs7541095 chr1:25761291 T/C cg02931644 chr1:25747376 RHCE 0.33 7.12 0.36 6.2e-12 Erythrocyte sedimentation rate; LIHC cis rs4891159 0.536 rs690392 chr18:74152618 G/A cg24786174 chr18:74118243 ZNF516 0.82 16.35 0.66 8.67e-45 Longevity; LIHC trans rs6598955 0.671 rs12145403 chr1:26597189 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.75 -8.79 -0.43 7.25e-17 Obesity-related traits; LIHC trans rs11165623 0.792 rs1931180 chr1:96914049 C/T cg10631902 chr5:14652156 NA -0.35 -8.9 -0.43 3.4e-17 Hip circumference;Waist circumference; LIHC cis rs903552 1.000 rs12904206 chr15:102006294 C/T cg25677261 chr15:102009856 PCSK6 -0.44 -5.95 -0.31 6.77e-9 Diabetic kidney disease; LIHC cis rs35362007 0.530 rs11621250 chr14:96011442 C/T cg13511115 chr14:96000878 GLRX5;SNHG10;SCARNA13 0.79 6.64 0.34 1.22e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10504229 0.679 rs1596142 chr8:58032406 G/A cg02290350 chr8:58132656 NA 0.31 7.17 0.36 4.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg13409248 chr3:40428643 ENTPD3 -0.51 -8.62 -0.42 2.46e-16 Renal cell carcinoma; LIHC cis rs8180040 0.966 rs11719877 chr3:47425473 C/T cg16586182 chr3:47516702 SCAP -0.57 -10.91 -0.51 5.63e-24 Colorectal cancer; LIHC cis rs986417 0.901 rs10139995 chr14:60947177 G/T cg27398547 chr14:60952738 C14orf39 0.77 8.53 0.42 4.73e-16 Gut microbiota (bacterial taxa); LIHC cis rs62458065 0.513 rs7788809 chr7:32552622 T/A cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -7.14 -0.36 5.49e-12 Metabolite levels (HVA/MHPG ratio); LIHC trans rs11098499 0.954 rs7656252 chr4:120404268 T/C cg25214090 chr10:38739885 LOC399744 0.58 9.5 0.46 3.69e-19 Corneal astigmatism; LIHC cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg05368731 chr17:41323189 NBR1 0.72 12.25 0.55 7.76e-29 Menopause (age at onset); LIHC cis rs7727544 0.684 rs272874 chr5:131675046 A/G cg24060327 chr5:131705240 SLC22A5 0.44 5.86 0.3 1.06e-8 Blood metabolite levels; LIHC cis rs7909074 1.000 rs10900128 chr10:45393201 G/T cg04218760 chr10:45406644 TMEM72 -0.24 -7.49 -0.38 5.76e-13 Mean corpuscular volume; LIHC cis rs25645 0.760 rs11870683 chr17:38129841 T/A cg17467752 chr17:38218738 THRA -0.45 -7.39 -0.37 1.14e-12 Myeloid white cell count; LIHC trans rs1814175 0.765 rs1721990 chr11:49912154 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.9 0.35 2.48e-11 Height; LIHC cis rs9309473 0.607 rs2421488 chr2:73590625 C/T cg20560298 chr2:73613845 ALMS1 -0.44 -6.86 -0.35 3.22e-11 Metabolite levels; LIHC cis rs6860806 0.507 rs270601 chr5:131656997 T/C cg24060327 chr5:131705240 SLC22A5 -0.8 -12.51 -0.56 7.63e-30 Breast cancer; LIHC cis rs60871478 1.000 rs62432250 chr7:801792 C/G cg05535760 chr7:792225 HEATR2 0.79 11.26 0.52 3.25e-25 Cerebrospinal P-tau181p levels; LIHC cis rs2439831 0.850 rs7169988 chr15:44060435 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.41 0.33 4.92e-10 Lung cancer in ever smokers; LIHC cis rs796364 1.000 rs1658807 chr2:200767512 C/T cg23649088 chr2:200775458 C2orf69 0.48 5.73 0.3 2.18e-8 Schizophrenia; LIHC cis rs2279817 0.954 rs12143113 chr1:18018857 T/C cg21791023 chr1:18019539 ARHGEF10L 0.63 8.04 0.4 1.47e-14 Neuroticism; LIHC cis rs1577917 0.916 rs12661611 chr6:86553835 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.47 -0.37 6.61e-13 Response to antipsychotic treatment; LIHC cis rs12701220 0.522 rs12701455 chr7:1055409 A/G cg09177884 chr7:1199841 ZFAND2A -0.47 -5.87 -0.3 1.02e-8 Bronchopulmonary dysplasia; LIHC cis rs12291225 0.639 rs61883858 chr11:14294708 C/T cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.18e-31 Sense of smell; LIHC cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg03264133 chr6:25882463 NA 0.52 6.48 0.33 3.19e-10 Intelligence (multi-trait analysis); LIHC cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg24675658 chr1:53192096 ZYG11B 0.67 10.59 0.5 7.4e-23 Monocyte count; LIHC cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg27572855 chr1:25598939 RHD -0.38 -8.1 -0.4 9.63e-15 Erythrocyte sedimentation rate; LIHC cis rs7927592 0.913 rs10047412 chr11:68232912 T/C cg20283391 chr11:68216788 NA -0.51 -7.58 -0.38 3.27e-13 Total body bone mineral density; LIHC trans rs7615952 0.932 rs1976458 chr3:125647512 T/G cg07211511 chr3:129823064 LOC729375 -0.84 -10.47 -0.49 1.94e-22 Blood pressure (smoking interaction); LIHC cis rs34172651 0.583 rs4787649 chr16:24700215 C/T cg00339695 chr16:24857497 SLC5A11 -0.48 -7.7 -0.38 1.44e-13 Intelligence (multi-trait analysis); LIHC cis rs6442522 0.678 rs3732722 chr3:15507761 G/A cg16303742 chr3:15540471 COLQ 0.45 7.61 0.38 2.72e-13 Uric acid levels; LIHC cis rs9768139 0.935 rs10949715 chr7:158117246 G/T cg25566285 chr7:158114605 PTPRN2 0.25 7.43 0.37 8.78e-13 Calcium levels; LIHC cis rs703842 1.000 rs11172343 chr12:58188157 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.3 0.61 1.07e-36 Multiple sclerosis; LIHC cis rs5769765 0.773 rs11090920 chr22:50320105 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -8.81 -0.43 6.41e-17 Schizophrenia; LIHC cis rs10464366 0.746 rs62442210 chr7:39146328 G/T cg18850127 chr7:39170497 POU6F2 0.47 8.4 0.41 1.17e-15 IgG glycosylation; LIHC cis rs4660261 0.526 rs2485997 chr1:44345841 G/C cg12908607 chr1:44402522 ARTN -0.48 -8.11 -0.4 9.34e-15 Intelligence (multi-trait analysis); LIHC cis rs1385374 0.858 rs12305142 chr12:129277490 C/T cg09035930 chr12:129282057 SLC15A4 -0.49 -6.08 -0.31 3.21e-9 Systemic lupus erythematosus; LIHC cis rs2153535 0.504 rs4493781 chr6:8473941 G/C cg07606381 chr6:8435919 SLC35B3 0.82 12.26 0.55 6.73e-29 Motion sickness; LIHC cis rs3008870 1.000 rs2985811 chr1:67377722 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.6 0.67 8.6e-46 Lymphocyte percentage of white cells; LIHC cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs7647973 0.626 rs9830730 chr3:49675875 G/C cg03060546 chr3:49711283 APEH 0.61 7.03 0.36 1.09e-11 Menarche (age at onset); LIHC cis rs9733 0.596 rs72702570 chr1:150688196 C/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC trans rs1005277 0.579 rs2505194 chr10:38393881 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.16 -0.52 6.98e-25 Extrinsic epigenetic age acceleration; LIHC cis rs1691799 0.836 rs1184552 chr12:66756215 A/G cg16791601 chr12:66731901 HELB -0.54 -13.23 -0.58 1.53e-32 White blood cell count (basophil); LIHC cis rs5769765 0.908 rs138864 chr22:50204712 G/A cg26441486 chr22:50317300 CRELD2 0.35 5.87 0.3 1.02e-8 Schizophrenia; LIHC cis rs936229 0.954 rs936230 chr15:75145098 C/T cg14664628 chr15:75095509 CSK 0.84 13.94 0.6 2.78e-35 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs929354 0.772 rs1182365 chr7:157017255 A/T cg17757837 chr7:157058334 UBE3C -0.74 -12.05 -0.55 4.28e-28 Body mass index; LIHC cis rs9814567 1.000 rs6766818 chr3:134226159 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.86 -0.3 1.06e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9467773 0.869 rs1796521 chr6:26421392 T/C cg09904177 chr6:26538194 HMGN4 -0.49 -8.87 -0.43 4.05e-17 Intelligence (multi-trait analysis); LIHC trans rs62103177 0.714 rs7227962 chr18:77603283 T/G cg05926928 chr17:57297772 GDPD1 0.56 7.27 0.37 2.46e-12 Opioid sensitivity; LIHC cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 8.16 0.4 6.58e-15 Platelet count; LIHC cis rs5769765 0.862 rs9616380 chr22:50312225 T/C cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02249930 chr10:70166207 RUFY2 -0.54 -6.8 -0.35 4.57e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9649213 0.593 rs6969731 chr7:97924571 T/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.75 -0.3 2.03e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs17001868 0.568 rs9611316 chr22:40737027 A/G cg07138101 chr22:40742427 ADSL 0.54 6.4 0.33 5.03e-10 Mammographic density (dense area); LIHC cis rs4788570 0.615 rs10852502 chr16:71652072 C/A cg06353428 chr16:71660113 MARVELD3 1.4 13.76 0.6 1.39e-34 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.791 rs6914203 chr6:145899975 C/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.87 -0.3 1.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9733 0.565 rs11804276 chr1:150685761 T/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs17001868 0.568 rs9611318 chr22:40739414 C/G cg07138101 chr22:40742427 ADSL 0.54 6.4 0.33 5.03e-10 Mammographic density (dense area); LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.48 -6.79 -0.34 5.04e-11 Lymphocyte counts; LIHC cis rs2072499 0.750 rs72708291 chr1:156177285 A/T cg25208724 chr1:156163844 SLC25A44 0.7 7.8 0.39 7.48e-14 Testicular germ cell tumor; LIHC trans rs7618501 0.602 rs2071206 chr3:50160109 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.57 -9.25 -0.45 2.55e-18 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.602 rs10484530 chr6:167461562 C/T cg07741184 chr6:167504864 NA 0.35 8.18 0.4 5.67e-15 Crohn's disease; LIHC cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 8.97 0.44 1.94e-17 Mean platelet volume; LIHC cis rs10504229 0.679 rs6474100 chr8:58031161 G/A cg20607798 chr8:58055168 NA 0.46 6.71 0.34 7.96e-11 Developmental language disorder (linguistic errors); LIHC cis rs4689592 0.503 rs3857180 chr4:7073899 T/G cg26116260 chr4:7069785 GRPEL1 -1.04 -17.76 -0.69 1.89e-50 Monocyte percentage of white cells; LIHC cis rs12286929 0.679 rs11606814 chr11:115042513 G/T cg04055981 chr11:115044050 NA 0.4 6.7 0.34 8.6e-11 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7613875 0.641 rs6793528 chr3:50100188 C/A cg05623727 chr3:50126028 RBM5 -0.34 -5.82 -0.3 1.38e-8 Body mass index; LIHC cis rs9457247 0.602 rs12209395 chr6:167463914 C/T cg07741184 chr6:167504864 NA 0.32 7.27 0.37 2.53e-12 Crohn's disease; LIHC cis rs507080 1.000 rs659969 chr11:118549803 C/T cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC cis rs7520050 0.931 rs785472 chr1:46518288 T/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.93 0.31 7.49e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1552244 0.572 rs7645759 chr3:10157368 C/T cg00149659 chr3:10157352 C3orf10 0.89 8.57 0.42 3.56e-16 Alzheimer's disease; LIHC cis rs611744 0.647 rs647907 chr8:109251374 T/C cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs12586317 0.620 rs12437439 chr14:35585669 C/A cg05294307 chr14:35346193 BAZ1A -0.46 -6.77 -0.34 5.49e-11 Psoriasis; LIHC cis rs7223966 1.000 rs9908044 chr17:61747032 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.92e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2066819 1.000 rs74496027 chr12:56726340 C/T cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs8062405 0.755 rs2077031 chr16:28603168 T/A cg07451762 chr16:28383216 NA 0.39 6.91 0.35 2.38e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7582180 0.629 rs4851308 chr2:100971865 C/A cg14675211 chr2:100938903 LONRF2 0.54 8.46 0.42 8e-16 Intelligence (multi-trait analysis); LIHC cis rs1215050 0.904 rs260898 chr4:98706492 C/G cg05340658 chr4:99064831 C4orf37 -0.45 -5.77 -0.3 1.77e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1580019 0.523 rs13236410 chr7:32690663 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.04 19.88 0.73 5.56e-59 Cognitive ability; LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg19635926 chr16:89946313 TCF25 0.51 7.13 0.36 5.91e-12 Skin colour saturation; LIHC cis rs11628318 0.614 rs3783383 chr14:103177420 G/C cg01864069 chr14:103024347 NA 0.39 6.38 0.33 5.69e-10 Platelet count; LIHC cis rs16828019 0.929 rs12029321 chr1:41682530 G/C cg03962019 chr1:41807865 NA 0.5 7.32 0.37 1.84e-12 Intelligence (multi-trait analysis); LIHC cis rs7592578 0.599 rs62180992 chr2:191285732 A/G cg10560079 chr2:191398806 TMEM194B -0.76 -10.66 -0.5 4.28e-23 Diastolic blood pressure; LIHC trans rs7714584 1.000 rs10061105 chr5:150255185 C/G cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg18252515 chr7:66147081 NA -1.27 -16.34 -0.66 9.2e-45 Diabetic kidney disease; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg18635645 chr1:85667791 SYDE2 -0.41 -6.16 -0.32 2.03e-9 Urinary tract infection frequency; LIHC cis rs796364 0.951 rs281793 chr2:200847990 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.7 8.24 0.41 3.7e-15 Schizophrenia; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs7980687 0.628 rs2102949 chr12:123676763 G/A cg05973401 chr12:123451056 ABCB9 0.45 6.21 0.32 1.56e-9 Height;Educational attainment;Head circumference (infant); LIHC cis rs868036 0.718 rs16951275 chr15:68077168 T/C cg24579218 chr15:68104479 NA -0.34 -5.83 -0.3 1.27e-8 Restless legs syndrome; LIHC cis rs11969893 0.737 rs1856131 chr6:101407104 C/G cg12253828 chr6:101329408 ASCC3 0.98 12.36 0.56 2.84e-29 Economic and political preferences (immigration/crime); LIHC cis rs3741404 0.609 rs592271 chr11:63872029 G/T cg05016508 chr11:63871570 FLRT1;MACROD1 0.42 6.68 0.34 9.97e-11 Platelet count; LIHC trans rs4332037 0.851 rs34040190 chr7:1920356 G/A cg11693508 chr17:37793320 STARD3 0.67 6.87 0.35 3.01e-11 Bipolar disorder; LIHC cis rs40363 0.645 rs250633 chr16:3523002 C/T cg00484396 chr16:3507460 NAT15 0.43 8.29 0.41 2.54e-15 Tuberculosis; LIHC cis rs7937890 0.505 rs4403769 chr11:14450176 C/T cg22961513 chr11:14280813 SPON1 -0.4 -6.0 -0.31 4.91e-9 Mitochondrial DNA levels; LIHC cis rs4979906 1.000 rs4979907 chr10:79451969 C/A cg07817648 chr10:79422355 NA -0.32 -6.85 -0.35 3.47e-11 Mortality in heart failure; LIHC trans rs1814175 0.817 rs10839401 chr11:49876144 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -22.99 -0.78 2.18e-71 Height; LIHC cis rs34779708 0.931 rs68039650 chr10:35385499 C/A cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11673344 0.704 rs517110 chr19:37422394 G/A cg27390819 chr19:37464633 NA -0.51 -6.07 -0.31 3.38e-9 Obesity-related traits; LIHC cis rs7635838 0.859 rs7632040 chr3:11427455 A/G cg00170343 chr3:11313890 ATG7 0.45 7.16 0.36 5.09e-12 HDL cholesterol; LIHC cis rs2153535 0.580 rs1328862 chr6:8526681 A/T cg23788917 chr6:8435910 SLC35B3 0.63 8.88 0.43 3.76e-17 Motion sickness; LIHC cis rs921968 0.608 rs495855 chr2:219357858 A/G cg17980119 chr2:219472607 PLCD4 0.36 6.25 0.32 1.25e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs13223928 0.621 rs10228451 chr7:3150859 C/G cg19214707 chr7:3157722 NA 0.41 7.54 0.38 4.37e-13 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs2932538 0.961 rs4240534 chr1:113175429 T/A cg22162597 chr1:113214053 CAPZA1 -0.73 -11.26 -0.52 3.07e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs6831352 0.879 rs1230154 chr4:99988659 C/T cg12011299 chr4:100065546 ADH4 0.58 9.98 0.47 9.4e-21 Alcohol dependence; LIHC cis rs600806 0.714 rs12137189 chr1:110013215 A/G cg23091122 chr1:110024289 SYPL2 -0.5 -6.85 -0.35 3.38e-11 Intelligence (multi-trait analysis); LIHC cis rs7769051 1.000 rs5006218 chr6:133126220 T/G cg07930552 chr6:133119739 C6orf192 0.65 6.46 0.33 3.51e-10 Type 2 diabetes nephropathy; LIHC cis rs8062405 0.755 rs4787456 chr16:28559573 C/T cg07382826 chr16:28625726 SULT1A1 0.49 7.68 0.38 1.74e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2857078 0.720 rs9906669 chr17:42305706 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.65 9.61 0.46 1.59e-19 Red cell distribution width;Reticulocyte count; LIHC cis rs796364 0.806 rs12616905 chr2:201007764 C/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs600806 0.850 rs10776806 chr1:109952127 G/A cg23091122 chr1:110024289 SYPL2 -0.45 -5.96 -0.31 6.44e-9 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.586 rs11713185 chr3:161111357 C/G cg17135325 chr3:160939158 NMD3 0.47 7.11 0.36 6.97e-12 Morning vs. evening chronotype; LIHC cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg20607798 chr8:58055168 NA 0.61 7.51 0.38 5.2e-13 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg06634786 chr22:41940651 POLR3H 0.8 9.02 0.44 1.43e-17 Vitiligo; LIHC cis rs13161895 0.818 rs78282770 chr5:179483686 T/A cg02702477 chr5:179499311 RNF130 0.89 12.04 0.55 4.51e-28 LDL cholesterol; LIHC cis rs8027181 1.000 rs7166595 chr15:73094204 A/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.45 6.92 0.35 2.23e-11 Triglyceride levels; LIHC cis rs1799949 0.965 rs799917 chr17:41244936 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.07 0.31 3.36e-9 Menopause (age at onset); LIHC cis rs1144333 0.655 rs76416835 chr1:76341511 G/T cg03433033 chr1:76189801 ACADM 0.54 7.45 0.37 7.82e-13 Attention function in attention deficit hyperactive disorder; LIHC trans rs3821902 0.547 rs56237630 chr3:64049375 C/A cg22906524 chr22:19960525 ARVCF -0.49 -6.04 -0.31 3.94e-9 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24926775 chr1:151584391 SNX27 0.43 7.01 0.35 1.3e-11 Cognitive function; LIHC cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9921222 0.500 rs11645742 chr16:367516 C/T cg08923669 chr16:420230 MRPL28 -0.47 -6.18 -0.32 1.81e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs7238033 0.602 rs10460034 chr18:43311399 C/T cg20610511 chr18:43302872 SLC14A1 0.38 6.34 0.32 7.44e-10 Bladder cancer; LIHC cis rs6952808 0.771 rs10265944 chr7:1918337 C/T cg14004847 chr7:1930337 MAD1L1 -0.52 -7.43 -0.37 8.62e-13 Bipolar disorder and schizophrenia; LIHC cis rs2836950 0.545 rs2297256 chr21:40558421 C/T cg11890956 chr21:40555474 PSMG1 -0.48 -7.82 -0.39 6.5e-14 Menarche (age at onset); LIHC cis rs10751667 1.000 rs12798036 chr11:947585 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.41 0.53 8.76e-26 Alzheimer's disease (late onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00221035 chr7:7222342 C1GALT1 -0.49 -6.27 -0.32 1.08e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9372253 0.967 rs9400379 chr6:110713783 A/G cg01119278 chr6:110721349 DDO -0.3 -6.3 -0.32 9.18e-10 Platelet distribution width; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06594919 chr10:102827590 NA 0.48 6.94 0.35 2.02e-11 Pancreatic cancer; LIHC cis rs6831352 0.918 rs2602896 chr4:100046207 C/T cg12011299 chr4:100065546 ADH4 -0.64 -10.47 -0.49 1.94e-22 Alcohol dependence; LIHC cis rs796364 0.806 rs11679676 chr2:201040981 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.68 -5.99 -0.31 5.38e-9 Schizophrenia; LIHC cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg06634786 chr22:41940651 POLR3H 0.82 9.05 0.44 1.13e-17 Vitiligo; LIHC cis rs8062405 0.755 rs4788076 chr16:28570005 C/T cg07382826 chr16:28625726 SULT1A1 0.5 8.03 0.4 1.55e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs5769765 0.955 rs9616366 chr22:50301178 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -9.24 -0.45 2.71e-18 Schizophrenia; LIHC cis rs2274273 0.712 rs17832311 chr14:55534466 A/G cg01864836 chr14:55583639 NA -0.38 -6.51 -0.33 2.74e-10 Protein biomarker; LIHC cis rs10752881 0.652 rs10911262 chr1:183114956 A/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.49 0.49 1.69e-22 Colorectal cancer; LIHC cis rs1023500 0.573 rs6002592 chr22:42476754 A/C cg15557168 chr22:42548783 NA 0.43 6.83 0.35 3.94e-11 Schizophrenia; LIHC cis rs9303401 0.659 rs17741087 chr17:56550300 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.92 12.58 0.56 4.44e-30 Cognitive test performance; LIHC cis rs7116495 0.609 rs11235444 chr11:71831859 G/A cg26138937 chr11:71823887 C11orf51 1.32 10.9 0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs4924935 0.781 rs2472694 chr17:18848498 A/G cg26378065 chr17:18585709 ZNF286B 0.53 5.88 0.3 9.67e-9 Pancreatic cancer; LIHC cis rs10193935 0.901 rs9808509 chr2:42479644 T/C cg27598129 chr2:42591480 NA -0.72 -10.44 -0.49 2.54e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg02782426 chr3:40428986 ENTPD3 0.34 6.33 0.32 7.63e-10 Renal cell carcinoma; LIHC cis rs1728785 0.818 rs1728772 chr16:68584526 C/T cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs7224737 1.000 rs9915255 chr17:40284191 C/T cg00647820 chr17:40259828 DHX58 -0.27 -5.71 -0.3 2.46e-8 Fibrinogen levels; LIHC cis rs7312933 0.703 rs11181380 chr12:42616040 A/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 7.53 0.38 4.5e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg23262073 chr20:60523788 NA -0.3 -6.21 -0.32 1.56e-9 Body mass index; LIHC cis rs10751667 0.643 rs10794343 chr11:925493 C/T cg11406765 chr11:980039 AP2A2 -0.34 -5.71 -0.3 2.46e-8 Alzheimer's disease (late onset); LIHC cis rs2380220 0.541 rs72928283 chr6:96082490 A/C cg23517279 chr6:96025343 MANEA -0.61 -6.08 -0.31 3.23e-9 Behavioural disinhibition (generation interaction); LIHC cis rs79057730 0.599 rs9458 chr7:825494 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.78 -9.06 -0.44 1.06e-17 Initial pursuit acceleration; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg20607798 chr8:58055168 NA 0.63 7.96 0.4 2.64e-14 Developmental language disorder (linguistic errors); LIHC cis rs7552404 0.961 rs17587071 chr1:76225083 A/C cg03433033 chr1:76189801 ACADM 0.66 9.23 0.45 2.8e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs25645 0.800 rs11078935 chr17:38192137 T/G cg17344932 chr17:38183730 MED24;SNORD124 0.76 14.73 0.62 2.16e-38 Myeloid white cell count; LIHC cis rs7618501 1.000 rs1049256 chr3:49763338 T/C cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.752 rs676882 chr17:37433424 A/T cg07936489 chr17:37558343 FBXL20 0.86 11.26 0.52 3.21e-25 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg08677398 chr8:58056175 NA 0.39 6.06 0.31 3.68e-9 Developmental language disorder (linguistic errors); LIHC trans rs7219021 1.000 rs57185954 chr17:46844961 T/C cg14968300 chr8:23585186 NA -0.35 -6.44 -0.33 3.97e-10 Schizophrenia or bipolar disorder; LIHC cis rs3096299 0.874 rs3102342 chr16:89451575 T/C cg06640241 chr16:89574553 SPG7 0.64 10.15 0.48 2.43e-21 Multiple myeloma (IgH translocation); LIHC cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.7 8.35 0.41 1.74e-15 Mean platelet volume; LIHC cis rs9911578 1.000 rs368186 chr17:56736659 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg20887711 chr4:1340912 KIAA1530 0.61 9.85 0.47 2.59e-20 Obesity-related traits; LIHC cis rs1707322 1.000 rs785506 chr1:46540652 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.68 -0.34 9.69e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs600806 0.821 rs3879447 chr1:109891403 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.71 -0.38 1.36e-13 Intelligence (multi-trait analysis); LIHC cis rs1494950 0.661 rs55952030 chr4:14987310 T/C cg12377275 chr4:15005593 CPEB2 -0.79 -6.68 -0.34 9.49e-11 Political ideology; LIHC cis rs870825 0.616 rs6817521 chr4:185649827 A/G cg04058563 chr4:185651563 MLF1IP -0.52 -5.79 -0.3 1.61e-8 Blood protein levels; LIHC cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.03 0.51 2.09e-24 Colorectal cancer; LIHC cis rs2153535 0.580 rs9406169 chr6:8509470 A/T cg21535247 chr6:8435926 SLC35B3 0.63 8.65 0.42 2.02e-16 Motion sickness; LIHC cis rs7224737 1.000 rs731152 chr17:40279680 G/A cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs11718455 0.767 rs4682924 chr3:43992760 G/A cg08738300 chr3:44038990 NA 0.52 8.85 0.43 4.83e-17 Coronary artery disease; LIHC cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg07061783 chr6:25882402 NA 0.43 6.24 0.32 1.31e-9 Blood metabolite levels; LIHC cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg05368731 chr17:41323189 NBR1 0.71 12.04 0.55 4.57e-28 Menopause (age at onset); LIHC cis rs2019216 0.542 rs3829569 chr17:21909222 T/C cg22648282 chr17:21454238 C17orf51 -0.44 -7.44 -0.37 8.32e-13 Pelvic organ prolapse; LIHC cis rs11577318 0.853 rs4471263 chr1:26622700 C/T cg10402321 chr1:26617780 UBXN11 -0.37 -5.8 -0.3 1.53e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg00091569 chr3:40428383 ENTPD3 -0.38 -6.24 -0.32 1.26e-9 Renal cell carcinoma; LIHC cis rs1570884 0.516 rs9535268 chr13:50175478 C/A cg03651054 chr13:50194643 NA 0.38 6.63 0.34 1.3e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC trans rs61931739 0.500 rs11836198 chr12:34552782 T/C cg26384229 chr12:38710491 ALG10B 0.63 8.01 0.4 1.76e-14 Morning vs. evening chronotype; LIHC cis rs757081 0.667 rs476890 chr11:17209962 A/G cg15432903 chr11:17409602 KCNJ11 -0.44 -6.08 -0.31 3.26e-9 Systolic blood pressure; LIHC trans rs9929218 0.581 rs12185157 chr16:68784587 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.86 18.23 0.7 2.29e-52 Colorectal cancer; LIHC cis rs9911578 1.000 rs9898626 chr17:56698219 C/G cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs15676 0.783 rs11515530 chr9:131576367 C/T cg00228799 chr9:131580591 ENDOG -0.47 -6.84 -0.35 3.56e-11 Blood metabolite levels; LIHC cis rs9309711 0.506 rs9284794 chr2:3492052 G/A cg10845886 chr2:3471009 TTC15 -0.43 -8.02 -0.4 1.75e-14 Neurofibrillary tangles; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 21.86 0.76 6.43e-67 Prudent dietary pattern; LIHC cis rs7512552 0.839 rs2264418 chr1:150368579 G/A cg15654264 chr1:150340011 RPRD2 0.68 11.27 0.52 2.96e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2832191 0.671 rs2409332 chr21:30512779 G/A cg24692254 chr21:30365293 RNF160 -0.42 -6.57 -0.33 1.88e-10 Dental caries; LIHC cis rs17604090 0.529 rs2392128 chr7:29711139 A/G cg19413766 chr7:29689036 LOC646762 0.58 6.08 0.31 3.19e-9 Facial emotion recognition;Facial emotion recognition (sad faces); LIHC cis rs6912958 0.967 rs6905947 chr6:88161949 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.08 -0.36 8.34e-12 Monocyte percentage of white cells; LIHC cis rs1865760 0.566 rs2032445 chr6:26044812 T/A cg18357526 chr6:26021779 HIST1H4A 0.46 6.83 0.35 3.79e-11 Height; LIHC cis rs7772486 0.817 rs9386145 chr6:146363519 A/T cg23711669 chr6:146136114 FBXO30 0.6 10.67 0.5 3.87e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs589448 0.902 rs528974 chr12:69765918 A/T cg14784868 chr12:69753453 YEATS4 0.98 22.84 0.78 9.05e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg11062466 chr8:58055876 NA 0.5 6.9 0.35 2.54e-11 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.712 rs167930 chr21:44946625 G/A cg04455712 chr21:45112962 RRP1B 0.44 7.57 0.38 3.54e-13 Mean corpuscular volume; LIHC cis rs2153535 0.580 rs6597322 chr6:8449952 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs13161895 0.941 rs3797764 chr5:179439345 A/G cg02702477 chr5:179499311 RNF130 -0.74 -10.27 -0.49 9.85e-22 LDL cholesterol; LIHC cis rs9733 0.543 rs72702558 chr1:150683251 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg11663144 chr21:46675770 NA -0.32 -5.94 -0.31 6.94e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs11098499 0.954 rs7687843 chr4:120421211 C/T cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Bipolar disorder; LIHC cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg00166722 chr3:10149974 C3orf24 0.48 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC cis rs2777491 0.507 rs34040639 chr15:41760807 A/G cg18705301 chr15:41695430 NDUFAF1 -1.25 -18.52 -0.71 1.55e-53 Ulcerative colitis; LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg21782813 chr7:2030301 MAD1L1 0.55 10.2 0.48 1.71e-21 Bipolar disorder and schizophrenia; LIHC cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg04025307 chr7:1156635 C7orf50 0.56 9.17 0.44 4.69e-18 Longevity;Endometriosis; LIHC cis rs3768617 0.811 rs12022720 chr1:183017223 A/G ch.1.3577855R chr1:183094577 LAMC1 0.47 7.54 0.38 4.21e-13 Fuchs's corneal dystrophy; LIHC cis rs9457247 0.756 rs2345572 chr6:167403441 A/T cg12798992 chr6:167411361 FGFR1OP 0.53 8.23 0.41 3.96e-15 Crohn's disease; LIHC cis rs4727027 0.933 rs1468369 chr7:148839840 G/C cg23583168 chr7:148888333 NA -0.73 -10.47 -0.49 1.93e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs1506636 1.000 rs2896332 chr7:123297223 A/T cg03229431 chr7:123269106 ASB15 -0.61 -12.04 -0.55 4.38e-28 Plateletcrit;Platelet count; LIHC cis rs1878931 0.535 rs10852706 chr16:3412582 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.68 8.88 0.43 3.82e-17 Body mass index (adult); LIHC cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg18252515 chr7:66147081 NA -1.26 -16.43 -0.66 3.87e-45 Diabetic kidney disease; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.47 0.56 1.09e-29 Prudent dietary pattern; LIHC cis rs5995875 0.524 rs73171017 chr22:41060853 A/T cg14879645 chr22:41048474 NA 0.4 5.82 0.3 1.35e-8 Breast size; LIHC cis rs2479724 0.868 rs2249703 chr6:41814760 A/G cg17623882 chr6:41773611 USP49 -0.55 -8.8 -0.43 6.88e-17 Menarche (age at onset); LIHC cis rs7149242 0.849 rs10146962 chr14:101170540 A/G cg18089426 chr14:101175970 NA 0.39 6.1 0.31 2.91e-9 Platelet count; LIHC cis rs2153535 0.580 rs6913100 chr6:8456855 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.77 0.43 8.47e-17 Motion sickness; LIHC cis rs2637266 0.655 rs861744 chr10:78519132 T/G cg18941641 chr10:78392320 NA 0.28 6.05 0.31 3.76e-9 Pulmonary function; LIHC cis rs10193935 1.000 rs4494804 chr2:42395946 A/T cg27598129 chr2:42591480 NA -0.73 -11.29 -0.52 2.5e-25 Colonoscopy-negative controls vs population controls; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg08355568 chr6:7108248 RREB1 -0.44 -6.16 -0.32 2.07e-9 Bilirubin levels; LIHC cis rs798554 0.723 rs798518 chr7:2777825 A/G cg04166393 chr7:2884313 GNA12 0.45 6.35 0.32 6.81e-10 Height; LIHC cis rs1707322 0.721 rs6699418 chr1:46100181 G/A cg03146154 chr1:46216737 IPP 0.57 9.96 0.47 1.13e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7918232 0.882 rs788237 chr10:27457932 C/T cg14442939 chr10:27389572 ANKRD26 -0.74 -7.06 -0.36 9.19e-12 Breast cancer; LIHC cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg07061783 chr6:25882402 NA -0.46 -6.49 -0.33 3.02e-10 Blood metabolite levels; LIHC cis rs1801251 0.964 rs7589201 chr2:233724536 A/G cg08000102 chr2:233561755 GIGYF2 -0.76 -11.64 -0.53 1.33e-26 Coronary artery disease; LIHC trans rs1005277 0.505 rs200937 chr10:38135772 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.47 -0.33 3.34e-10 Extrinsic epigenetic age acceleration; LIHC cis rs1419980 0.730 rs11054899 chr12:7774445 C/T cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC cis rs34330 0.562 rs11055024 chr12:12858969 A/G cg04607235 chr12:12878440 APOLD1 -0.75 -9.25 -0.45 2.44e-18 Systemic lupus erythematosus; LIHC cis rs2576037 0.583 rs9916891 chr18:44493521 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -6.89 -0.35 2.64e-11 Personality dimensions; LIHC cis rs16958440 0.541 rs11876448 chr18:44644530 G/A cg17192377 chr18:44677553 HDHD2 0.49 6.2 0.32 1.62e-9 Sitting height ratio; LIHC cis rs274567 0.501 rs2631368 chr5:131705297 T/G cg24060327 chr5:131705240 SLC22A5 0.8 12.63 0.56 2.75e-30 Blood metabolite levels; LIHC cis rs4319547 0.915 rs7966094 chr12:123115771 A/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.87 -0.39 4.59e-14 Body mass index; LIHC cis rs7084416 0.517 rs75453629 chr10:82010658 C/T cg01528321 chr10:82214614 TSPAN14 -0.53 -7.0 -0.35 1.33e-11 Post bronchodilator FEV1; LIHC cis rs797680 0.856 rs693737 chr1:93724924 G/A cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.89 0.3 9.29e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs2153535 0.601 rs718504 chr6:8527512 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.72 0.54 6.76e-27 Motion sickness; LIHC cis rs7772486 0.790 rs2254283 chr6:146204289 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.18 0.52 6.23e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs757081 0.667 rs7108067 chr11:17200220 G/A cg15432903 chr11:17409602 KCNJ11 -0.42 -5.86 -0.3 1.07e-8 Systolic blood pressure; LIHC cis rs875971 1.000 rs7792762 chr7:66004138 T/C cg18876405 chr7:65276391 NA 0.35 6.49 0.33 3.02e-10 Aortic root size; LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg22528358 chr1:107598549 PRMT6 0.71 11.67 0.53 1.07e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11583043 1.000 rs7521424 chr1:101475901 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.58 7.83 0.39 6.12e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs1790761 0.667 rs11227837 chr11:67336424 A/T cg00290607 chr11:67383545 NA 0.38 5.77 0.3 1.74e-8 Mean corpuscular volume; LIHC cis rs921968 0.613 rs2912737 chr2:219545789 A/G cg02985541 chr2:219472218 PLCD4 -0.39 -6.52 -0.33 2.58e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg07061783 chr6:25882402 NA 0.47 6.03 0.31 4.26e-9 Intelligence (multi-trait analysis); LIHC cis rs2842992 0.747 rs9365095 chr6:160192928 T/G cg11366901 chr6:160182831 ACAT2 0.92 15.43 0.64 3.78e-41 Age-related macular degeneration (geographic atrophy); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08334199 chr2:178128998 NFE2L2 -0.51 -6.11 -0.31 2.78e-9 Systolic blood pressure; LIHC cis rs1707322 0.752 rs11211152 chr1:46114157 C/T cg03146154 chr1:46216737 IPP 0.57 9.74 0.47 6.17e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8062405 0.755 rs111693583 chr16:28583610 C/T cg07382826 chr16:28625726 SULT1A1 0.48 7.54 0.38 4.35e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2404602 0.655 rs8028294 chr15:77084877 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.88 0.3 9.81e-9 Blood metabolite levels; LIHC cis rs7927771 0.524 rs11039345 chr11:47720228 A/G cg20307385 chr11:47447363 PSMC3 0.73 10.99 0.51 2.8e-24 Subjective well-being; LIHC cis rs10779751 0.734 rs12569242 chr1:11127511 A/C cg08854313 chr1:11322531 MTOR 0.65 9.9 0.47 1.74e-20 Body mass index; LIHC cis rs9467773 0.838 rs3734540 chr6:26463321 A/C cg11502198 chr6:26597334 ABT1 0.44 6.34 0.32 7.33e-10 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC cis rs4253772 0.591 rs9627324 chr22:46656511 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.73 6.63 0.34 1.35e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs9399135 0.967 rs11755229 chr6:135369913 A/G cg22676075 chr6:135203613 NA 0.4 6.36 0.33 6.58e-10 Red blood cell count; LIHC cis rs35146811 0.771 rs1060544 chr7:99613476 C/T cg13334819 chr7:99746414 C7orf59 -0.56 -7.97 -0.4 2.43e-14 Coronary artery disease; LIHC cis rs2257205 0.667 rs6503874 chr17:56780459 C/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.56 -0.33 2e-10 Pancreatic cancer; LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg05185784 chr16:90016020 DEF8 -0.44 -5.96 -0.31 6.27e-9 Skin colour saturation; LIHC cis rs9790314 0.663 rs12639128 chr3:160639645 A/G cg03342759 chr3:160939853 NMD3 0.56 7.29 0.37 2.19e-12 Morning vs. evening chronotype; LIHC cis rs2841277 0.708 rs28600075 chr14:105408315 T/C cg15352829 chr14:105391018 PLD4 -0.43 -9.23 -0.45 2.83e-18 Rheumatoid arthritis; LIHC cis rs561341 1.000 rs8073186 chr17:30244956 T/C cg13647721 chr17:30228624 UTP6 0.77 7.58 0.38 3.18e-13 Hip circumference adjusted for BMI; LIHC cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg11644478 chr21:40555479 PSMG1 -0.56 -6.74 -0.34 6.58e-11 Cognitive function; LIHC cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.09e-8 Bipolar disorder; LIHC cis rs918629 0.567 rs13361341 chr5:95250273 A/T cg10483112 chr5:95245456 ELL2 -0.38 -7.04 -0.36 1.08e-11 IgG glycosylation; LIHC cis rs2281845 0.859 rs4915217 chr1:201077470 T/A cg24849736 chr1:201084428 NA -0.33 -5.77 -0.3 1.73e-8 Permanent tooth development; LIHC cis rs8060686 0.544 rs1124993 chr16:68114626 T/C cg05110241 chr16:68378359 PRMT7 -0.53 -6.08 -0.31 3.16e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs11212260 0.655 rs2276271 chr11:107328544 C/T cg25435332 chr11:107328525 CWF19L2 0.8 8.44 0.42 8.85e-16 IgG glycosylation; LIHC cis rs7131987 0.622 rs7294598 chr12:29531989 A/C cg05697976 chr12:29376483 FAR2 -0.31 -6.27 -0.32 1.07e-9 QT interval; LIHC cis rs4819052 0.851 rs13050359 chr21:46672671 T/G cg11663144 chr21:46675770 NA -0.31 -5.83 -0.3 1.26e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11098699 0.821 rs13120866 chr4:124199293 A/G cg09941581 chr4:124220074 SPATA5 0.31 6.2 0.32 1.6e-9 Mosquito bite size; LIHC cis rs3736485 0.966 rs12443007 chr15:51892192 G/A cg08986416 chr15:51914746 DMXL2 -0.4 -5.73 -0.3 2.22e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11673344 0.503 rs1667370 chr19:37490220 A/T cg27390819 chr19:37464633 NA -0.47 -6.12 -0.31 2.6e-9 Obesity-related traits; LIHC cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg02951883 chr7:2050386 MAD1L1 -0.63 -9.64 -0.46 1.26e-19 Bipolar disorder and schizophrenia; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg11905131 chr22:24372483 LOC391322 -0.67 -9.95 -0.47 1.16e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs589448 0.902 rs315134 chr12:69762713 G/A cg14784868 chr12:69753453 YEATS4 0.98 22.81 0.78 1.15e-70 Cerebrospinal fluid biomarker levels; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg09033563 chr22:24373618 LOC391322 0.43 5.86 0.3 1.07e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg26939375 chr7:64535504 NA 0.43 7.21 0.36 3.56e-12 Calcium levels; LIHC cis rs35306767 0.903 rs7067865 chr10:908387 C/T cg26597838 chr10:835615 NA 1.19 13.99 0.6 1.82e-35 Eosinophil percentage of granulocytes; LIHC cis rs561341 0.800 rs7209766 chr17:30234848 T/A cg13647721 chr17:30228624 UTP6 0.73 8.08 0.4 1.13e-14 Hip circumference adjusted for BMI; LIHC cis rs11229555 0.645 rs12805062 chr11:58214584 A/G cg15696309 chr11:58395628 NA -0.65 -7.63 -0.38 2.37e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs3783890 1.000 rs12881444 chr14:93784302 T/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.32 0.32 8.12e-10 Body mass index; LIHC cis rs9910055 0.530 rs7222349 chr17:42304644 C/T cg13607699 chr17:42295918 UBTF 0.66 11.69 0.53 8.68e-27 Total body bone mineral density; LIHC cis rs6502050 0.835 rs7220639 chr17:80146866 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.92 -0.31 7.68e-9 Life satisfaction; LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg07234388 chr1:156261841 TMEM79 0.52 9.39 0.45 8.5e-19 Tonsillectomy; LIHC cis rs34779708 0.832 rs12764283 chr10:35530460 G/A cg03585969 chr10:35415529 CREM 0.86 12.57 0.56 4.89e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7520050 0.807 rs28378621 chr1:46189554 T/C cg24296786 chr1:45957014 TESK2 -0.4 -5.92 -0.31 7.63e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6456156 0.565 rs12525345 chr6:167478875 T/C cg12798992 chr6:167411361 FGFR1OP 0.44 6.76 0.34 5.87e-11 Primary biliary cholangitis; LIHC cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs858239 0.539 rs28624974 chr7:23188936 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.96 0.35 1.71e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs1873147 0.569 rs8034365 chr15:63309203 C/T cg12160578 chr15:63334699 TPM1 0.67 8.87 0.43 4.13e-17 Orofacial clefts; LIHC cis rs801193 0.967 rs3800823 chr7:66147110 C/A cg18876405 chr7:65276391 NA -0.41 -6.99 -0.35 1.48e-11 Aortic root size; LIHC cis rs3815308 0.530 rs2269880 chr19:2195611 T/C cg09261902 chr19:2140048 AP3D1 0.37 6.29 0.32 9.63e-10 Breast cancer; LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs651907 0.514 rs10936744 chr3:101433440 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.51 0.53 4.06e-26 Colorectal cancer; LIHC cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.55 8.6 0.42 2.85e-16 Schizophrenia; LIHC cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg11301795 chr4:187892539 NA -0.27 -7.01 -0.35 1.29e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7769051 1.000 rs9493445 chr6:133125409 C/T cg22852734 chr6:133119734 C6orf192 0.92 9.44 0.45 5.9e-19 Type 2 diabetes nephropathy; LIHC cis rs12478296 1.000 rs7603984 chr2:243047294 A/G cg05760424 chr2:242988095 NA -0.51 -6.79 -0.34 4.88e-11 Obesity-related traits; LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg08280861 chr8:58055591 NA 0.51 6.39 0.33 5.56e-10 Developmental language disorder (linguistic errors); LIHC cis rs67460515 0.563 rs4521287 chr3:160812752 C/T cg17135325 chr3:160939158 NMD3 0.53 7.38 0.37 1.25e-12 Parkinson's disease; LIHC cis rs655641 1.000 rs1996108 chr11:85728030 T/C cg09030501 chr11:85779252 PICALM -0.51 -6.21 -0.32 1.56e-9 Platelet count; LIHC trans rs1422110 0.513 rs987280 chr5:85448604 C/T cg01787110 chr1:109008453 NBPF6 -0.3 -7.48 -0.37 6.45e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs523522 0.962 rs3759394 chr12:120933173 C/A cg27279351 chr12:120934652 DYNLL1 0.67 12.05 0.55 3.99e-28 High light scatter reticulocyte count; LIHC cis rs9457247 0.534 rs933243 chr6:167403873 A/C cg12798992 chr6:167411361 FGFR1OP 0.53 8.45 0.42 8.47e-16 Crohn's disease; LIHC cis rs9814567 1.000 rs7637227 chr3:134244155 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.99 -0.31 5.24e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs66887589 0.616 rs1052633 chr4:120215314 A/G cg09307838 chr4:120376055 NA 0.55 8.06 0.4 1.28e-14 Diastolic blood pressure; LIHC cis rs72781680 0.848 rs56218741 chr2:23977377 A/C cg08917208 chr2:24149416 ATAD2B 0.82 7.41 0.37 1.01e-12 Lymphocyte counts; LIHC cis rs9457247 0.765 rs9459838 chr6:167426599 C/G cg12798992 chr6:167411361 FGFR1OP 0.48 7.37 0.37 1.32e-12 Crohn's disease; LIHC cis rs9549367 0.713 rs2146750 chr13:113822530 A/G cg00898013 chr13:113819073 PROZ 0.35 5.75 0.3 1.96e-8 Platelet distribution width; LIHC cis rs896854 0.902 rs726816 chr8:95968413 T/G cg16049864 chr8:95962084 TP53INP1 -0.64 -12.04 -0.55 4.49e-28 Type 2 diabetes; LIHC trans rs7618501 0.521 rs952594 chr3:49908023 G/A cg21659725 chr3:3221576 CRBN 0.56 8.1 0.4 1e-14 Intelligence (multi-trait analysis); LIHC cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg24675658 chr1:53192096 ZYG11B 0.56 8.8 0.43 6.75e-17 Monocyte count; LIHC cis rs12220238 1.000 rs10824130 chr10:76008931 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.97 0.35 1.66e-11 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19857457 chr18:47018947 RPL17;SNORD58A;SNORD58B 0.4 6.14 0.32 2.34e-9 Cognitive function; LIHC cis rs2204008 0.599 rs2320526 chr12:38220405 T/A cg13010199 chr12:38710504 ALG10B 0.48 5.79 0.3 1.58e-8 Bladder cancer; LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg11766577 chr21:47581405 C21orf56 0.44 7.27 0.37 2.42e-12 Testicular germ cell tumor; LIHC cis rs743757 1.000 rs2236954 chr3:50425177 C/A cg05260129 chr3:50388622 TUSC4;CYB561D2 0.46 6.4 0.33 5.08e-10 Diastolic blood pressure; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg07332563 chr6:291687 DUSP22 0.47 6.58 0.34 1.78e-10 Menopause (age at onset); LIHC cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg07424592 chr7:64974309 NA 0.74 8.57 0.42 3.67e-16 Diabetic kidney disease; LIHC cis rs1005277 0.579 rs1740732 chr10:38491385 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.27 -0.32 1.07e-9 Extrinsic epigenetic age acceleration; LIHC trans rs8113308 1.000 rs8104737 chr19:52441697 T/G cg14959425 chr7:20447707 ITGB8 -0.48 -6.47 -0.33 3.34e-10 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs875971 0.545 rs73152714 chr7:65999628 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 7.0 0.35 1.34e-11 Aortic root size; LIHC cis rs1873147 0.569 rs12593531 chr15:63309936 C/G cg21584241 chr15:63341463 TPM1 0.44 6.33 0.32 7.58e-10 Orofacial clefts; LIHC cis rs3749237 0.595 rs35701831 chr3:49515000 A/C cg02487422 chr3:49467188 NICN1 0.39 6.09 0.31 3.12e-9 Resting heart rate; LIHC cis rs1008375 1.000 rs1860597 chr4:17657650 C/T cg15017067 chr4:17643749 FAM184B 0.34 5.83 0.3 1.29e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7923837 0.687 rs2185756 chr10:94430497 A/C cg25506282 chr10:94462361 NA 0.39 6.9 0.35 2.54e-11 Body mass index;Multiple sclerosis; LIHC cis rs7238033 0.624 rs9304322 chr18:43308198 G/T cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs11792861 0.781 rs874864 chr9:111728718 C/T cg05043794 chr9:111880884 C9orf5 -0.27 -6.44 -0.33 4.06e-10 Menarche (age at onset); LIHC cis rs6754311 0.773 rs1435576 chr2:136641882 A/T cg15123519 chr2:136567270 LCT -0.4 -8.1 -0.4 9.92e-15 Mosquito bite size; LIHC cis rs10876993 0.928 rs774890 chr12:58068388 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.3 -0.32 9.34e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs7937682 0.575 rs1940391 chr11:111776891 G/A cg09085632 chr11:111637200 PPP2R1B 0.92 13.82 0.6 8.34e-35 Primary sclerosing cholangitis; LIHC cis rs7309 0.935 rs10930013 chr2:162070325 G/A cg13854012 chr2:162103682 NA -0.35 -6.52 -0.33 2.47e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.7 0.46 8.04e-20 Electroencephalogram traits; LIHC trans rs2727020 0.619 rs1829979 chr11:49436875 T/G cg18944383 chr4:111397179 ENPEP 0.35 8.04 0.4 1.48e-14 Coronary artery disease; LIHC cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg06634786 chr22:41940651 POLR3H -0.78 -8.54 -0.42 4.57e-16 Vitiligo; LIHC cis rs826838 1.000 rs11168505 chr12:38939057 A/T cg13010199 chr12:38710504 ALG10B -0.57 -7.29 -0.37 2.11e-12 Heart rate; LIHC cis rs8072100 0.935 rs12943464 chr17:45690351 A/T cg08085267 chr17:45401833 C17orf57 0.39 5.93 0.31 7.3e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1018836 0.851 rs7007129 chr8:91629790 T/G cg16814680 chr8:91681699 NA -0.61 -9.77 -0.47 4.66e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7312774 0.618 rs4964195 chr12:107392778 T/C cg16260113 chr12:107380972 MTERFD3 1.02 13.21 0.58 1.75e-32 Severe influenza A (H1N1) infection; LIHC cis rs4407350 0.967 rs5765731 chr22:44922759 C/T cg11695653 chr22:44894386 LDOC1L -0.37 -6.0 -0.31 5.13e-9 Intelligence (multi-trait analysis); LIHC cis rs7903847 0.642 rs7078782 chr10:99168604 C/T cg20016023 chr10:99160130 RRP12 -0.43 -7.0 -0.35 1.35e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs8062405 1.000 rs62036621 chr16:28833299 C/A cg16576597 chr16:28551801 NUPR1 0.37 6.1 0.31 2.86e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs459482 1.000 rs461981 chr21:42794081 T/C cg14166395 chr21:42792516 MX1 0.69 9.99 0.48 8.77e-21 IgG glycosylation; LIHC cis rs11123170 0.640 rs931472 chr2:113969948 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.5 -6.41 -0.33 4.93e-10 Renal function-related traits (BUN); LIHC trans rs1005277 0.579 rs2800485 chr10:38542588 G/A cg17830980 chr10:43048298 ZNF37B -0.49 -9.44 -0.45 5.8e-19 Extrinsic epigenetic age acceleration; LIHC cis rs11711311 0.955 rs9881563 chr3:113414031 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 -0.44 -8.15 -0.4 6.71e-15 IgG glycosylation; LIHC cis rs798554 0.959 rs798558 chr7:2758935 T/G cg19346786 chr7:2764209 NA -0.41 -6.09 -0.31 3e-9 Height; LIHC cis rs1555322 0.505 rs591590 chr20:33866028 A/G cg03689076 chr20:33865952 NA -0.58 -6.7 -0.34 8.38e-11 Attention deficit hyperactivity disorder; LIHC cis rs1348850 0.874 rs6742951 chr2:178340766 G/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.92 14.27 0.61 1.49e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs651907 0.535 rs11711903 chr3:101500748 C/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.63 10.13 0.48 2.94e-21 Colorectal cancer; LIHC cis rs9457247 0.765 rs9457252 chr6:167433925 A/G cg12798992 chr6:167411361 FGFR1OP -0.49 -7.46 -0.37 7.19e-13 Crohn's disease; LIHC cis rs9427116 0.502 rs9427104 chr1:154589232 C/T cg17218026 chr1:154582156 ADAR 0.36 7.12 0.36 6.29e-12 Blood protein levels; LIHC cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg10802521 chr3:52805072 NEK4 -0.45 -7.42 -0.37 9.36e-13 Bipolar disorder; LIHC cis rs8067545 0.750 rs34290687 chr17:19991211 G/A cg13482628 chr17:19912719 NA 0.48 8.11 0.4 9.4e-15 Schizophrenia; LIHC cis rs9611565 0.570 rs12159188 chr22:42121125 A/T cg06634786 chr22:41940651 POLR3H 0.57 6.41 0.33 4.81e-10 Vitiligo; LIHC cis rs9640161 0.830 rs17173681 chr7:150059414 A/G cg17279839 chr7:150038598 RARRES2 -0.4 -8.04 -0.4 1.5e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs3741798 1.000 rs61922028 chr12:12487096 A/C cg08615371 chr12:12503544 MANSC1 0.97 8.2 0.41 4.91e-15 Cerebrospinal fluid biomarker levels; LIHC trans rs1814175 0.817 rs2866545 chr11:49630824 A/C cg15704280 chr7:45808275 SEPT13 -1.01 -22.7 -0.78 3.18e-70 Height; LIHC cis rs9467711 0.559 rs3799383 chr6:26510748 C/T cg12826209 chr6:26865740 GUSBL1 0.57 5.84 0.3 1.2e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs138857 0.515 rs9616375 chr22:50310600 G/A cg02269571 chr22:50332266 NA -1.03 -10.49 -0.49 1.68e-22 Mean platelet volume; LIHC trans rs11039798 0.920 rs9667596 chr11:48691193 T/C cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs8060686 0.545 rs10500543 chr16:68281311 T/C cg05110241 chr16:68378359 PRMT7 -0.61 -6.92 -0.35 2.23e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs9303401 0.659 rs34878689 chr17:56694330 G/A cg25039879 chr17:56429692 SUPT4H1 0.86 9.69 0.46 9e-20 Cognitive test performance; LIHC cis rs12477438 0.834 rs6757019 chr2:99676936 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.85 -0.65 8.31e-43 Chronic sinus infection; LIHC cis rs12644436 0.671 rs4693189 chr4:88787249 T/C cg06891869 chr4:88767617 MEPE 0.42 7.6 0.38 2.93e-13 HIV-1 viral setpoint; LIHC cis rs17270561 0.779 rs1165200 chr6:25875212 C/T cg16482183 chr6:26056742 HIST1H1C -0.53 -6.57 -0.33 1.92e-10 Iron status biomarkers; LIHC cis rs7582720 1.000 rs72934729 chr2:203737770 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs12477438 0.798 rs6704766 chr2:99642818 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -10.77 -0.5 1.69e-23 Chronic sinus infection; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg04282497 chr4:82350883 RASGEF1B 0.42 6.56 0.33 1.95e-10 Immature fraction of reticulocytes; LIHC trans rs35110281 0.627 rs11701746 chr21:44975137 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.47 6.44 0.33 4.09e-10 Mean corpuscular volume; LIHC cis rs1371867 0.846 rs1788196 chr8:101290088 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -8.9 -0.43 3.27e-17 Atrioventricular conduction; LIHC cis rs9611565 0.921 rs4822021 chr22:41726053 G/A cg06634786 chr22:41940651 POLR3H -0.63 -7.24 -0.36 2.92e-12 Vitiligo; LIHC cis rs858239 0.539 rs10247268 chr7:23187179 G/A cg18081818 chr7:23246105 NA -0.39 -5.75 -0.3 1.95e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs5758659 0.714 rs133373 chr22:42465788 G/A cg19513890 chr22:42538836 CYP2D7P1 -0.4 -7.99 -0.4 2.11e-14 Cognitive function; LIHC cis rs6545883 0.860 rs4671399 chr2:61458518 C/T cg14146966 chr2:61757674 XPO1 -0.43 -7.2 -0.36 3.95e-12 Tuberculosis; LIHC cis rs17253792 0.822 rs75232282 chr14:56067290 G/C cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC trans rs7120489 0.708 rs3812759 chr11:12443958 T/C cg08537300 chr5:179058959 NA 0.57 6.21 0.32 1.55e-9 Mortality in heart failure; LIHC cis rs4948102 0.595 rs10255049 chr7:56121304 G/A cg12555334 chr7:56120290 CCT6A;PSPH 0.36 6.18 0.32 1.82e-9 Plasma homocysteine levels (post-methionine load test); LIHC cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.21e-8 Menopause (age at onset); LIHC cis rs4728302 0.869 rs889825 chr7:133596227 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.54 0.33 2.24e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7772486 0.603 rs2223411 chr6:146028767 T/C cg13319975 chr6:146136371 FBXO30 0.55 8.83 0.43 5.63e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.61 -0.34 1.49e-10 Total body bone mineral density; LIHC cis rs13108904 0.517 rs7671242 chr4:1339875 G/A cg13395646 chr4:1353034 KIAA1530 -0.75 -10.69 -0.5 3.4e-23 Obesity-related traits; LIHC cis rs1789 0.839 rs9997068 chr4:15650990 T/C cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.85 -0.3 1.16e-8 Blood protein levels; LIHC cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs4237845 0.537 rs2002275 chr12:58283385 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.54 7.42 0.37 9.49e-13 Intelligence (multi-trait analysis); LIHC cis rs2235642 0.750 rs763152 chr16:1658056 T/C cg09025071 chr16:1593152 IFT140;TMEM204 0.31 6.13 0.31 2.43e-9 Coronary artery disease; LIHC trans rs1814175 0.935 rs7950947 chr11:49668369 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -21.75 -0.76 1.77e-66 Height; LIHC cis rs67460515 1.000 rs67460515 chr3:161068566 T/C cg03342759 chr3:160939853 NMD3 -0.56 -8.41 -0.41 1.12e-15 Parkinson's disease; LIHC cis rs11711311 0.712 rs10804510 chr3:113340700 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.33 -6.03 -0.31 4.26e-9 IgG glycosylation; LIHC cis rs7772486 0.754 rs9386134 chr6:146145508 G/A cg13319975 chr6:146136371 FBXO30 -0.41 -6.58 -0.34 1.74e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7551222 0.752 rs10900594 chr1:204470129 C/G cg20240347 chr1:204465584 NA -0.29 -5.93 -0.31 7.56e-9 Schizophrenia; LIHC cis rs4948275 0.530 rs10994747 chr10:63149922 A/G cg03237606 chr10:63212265 TMEM26 0.29 6.29 0.32 9.89e-10 Night sleep phenotypes; LIHC cis rs7659604 1.000 rs28640980 chr4:122664284 T/C cg19748678 chr4:122722346 EXOSC9 0.37 6.3 0.32 9.14e-10 Type 2 diabetes; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg13996397 chr19:1420048 DAZAP1 0.42 7.08 0.36 8.34e-12 Calcium levels; LIHC cis rs1552244 0.882 rs68080705 chr3:10025743 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.53 -0.49 1.17e-22 Alzheimer's disease; LIHC cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.1 17.12 0.68 6.77e-48 Gut microbiome composition (summer); LIHC cis rs4908760 0.539 rs6690928 chr1:8859491 G/C cg20416874 chr1:8611966 RERE -0.57 -10.28 -0.49 8.98e-22 Vitiligo; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02287918 chr21:30396957 USP16 -0.48 -7.36 -0.37 1.4e-12 Cognitive function; LIHC cis rs7927771 0.864 rs4752838 chr11:47466006 G/A cg20307385 chr11:47447363 PSMC3 -0.49 -6.4 -0.33 5.09e-10 Subjective well-being; LIHC cis rs4803468 0.967 rs13345590 chr19:41886455 T/G cg14132834 chr19:41945861 ATP5SL -0.39 -5.77 -0.3 1.78e-8 Height; LIHC cis rs798766 0.953 rs13123646 chr4:1740539 T/C cg21231739 chr4:1642635 FAM53A -0.38 -6.1 -0.31 2.82e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs11098499 0.913 rs68128210 chr4:120137819 T/G cg09307838 chr4:120376055 NA 0.52 7.57 0.38 3.48e-13 Corneal astigmatism; LIHC cis rs6502050 0.835 rs6502077 chr17:80122966 G/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs35306767 0.903 rs12769431 chr10:922633 T/C cg26597838 chr10:835615 NA 1.11 13.75 0.6 1.53e-34 Eosinophil percentage of granulocytes; LIHC cis rs7843479 1.000 rs727694 chr8:21849962 T/C cg17168535 chr8:21777572 XPO7 0.41 6.61 0.34 1.48e-10 Mean corpuscular volume; LIHC cis rs4665809 1.000 rs1371553 chr2:26262948 G/A cg27170947 chr2:26402098 FAM59B -0.68 -8.33 -0.41 1.97e-15 Gut microbiome composition (summer); LIHC cis rs35306767 0.951 rs61833265 chr10:990143 C/T cg20503657 chr10:835505 NA 0.99 9.66 0.46 1.12e-19 Eosinophil percentage of granulocytes; LIHC cis rs11719291 0.833 rs13074318 chr3:48816725 C/T cg00383909 chr3:49044727 WDR6 1.06 7.47 0.37 6.75e-13 Cognitive function; LIHC cis rs6088580 0.634 rs6088483 chr20:32984714 T/A cg08999081 chr20:33150536 PIGU -0.67 -13.34 -0.58 5.73e-33 Glomerular filtration rate (creatinine); LIHC cis rs9649465 0.967 rs13239184 chr7:123314618 G/T cg03229431 chr7:123269106 ASB15 -0.38 -8.08 -0.4 1.09e-14 Migraine; LIHC cis rs6748734 1.000 rs6748734 chr2:241837452 A/G cg09990169 chr2:241835740 C2orf54 -0.66 -9.15 -0.44 5.22e-18 Urinary metabolites; LIHC cis rs1707322 0.686 rs3014235 chr1:46091512 A/G cg06784218 chr1:46089804 CCDC17 -0.43 -7.78 -0.39 8.65e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7258465 0.965 rs2385088 chr19:18545540 A/G cg10790698 chr19:18539756 SSBP4 -0.37 -7.49 -0.38 5.79e-13 Breast cancer; LIHC cis rs4665809 1.000 rs6546726 chr2:26275116 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.71 -8.8 -0.43 6.82e-17 Gut microbiome composition (summer); LIHC cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg23172400 chr8:95962367 TP53INP1 -0.35 -7.71 -0.38 1.38e-13 Type 2 diabetes; LIHC cis rs2933343 0.700 rs2624910 chr3:128650275 G/C cg24203234 chr3:128598194 ACAD9 0.45 6.32 0.32 8.18e-10 IgG glycosylation; LIHC cis rs72627509 0.629 rs1277313 chr4:57903948 A/C cg16868167 chr4:57843880 C4orf14;POLR2B 0.49 7.33 0.37 1.65e-12 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4819052 1.000 rs13047688 chr21:46669290 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.69 9.16 0.44 4.88e-18 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.83 -10.74 -0.5 2.19e-23 Alzheimer's disease; LIHC cis rs9926296 0.572 rs2376878 chr16:89885161 G/A cg04287289 chr16:89883240 FANCA 0.57 9.75 0.47 5.52e-20 Vitiligo; LIHC trans rs8117834 0.574 rs6086336 chr20:8088710 C/T cg00593689 chr4:53575888 NA 0.38 6.38 0.33 5.83e-10 Chronic kidney disease; LIHC cis rs1577917 0.839 rs12216103 chr6:86571128 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.47 -0.37 6.61e-13 Response to antipsychotic treatment; LIHC cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg09222892 chr1:25734099 RHCE -0.48 -8.89 -0.43 3.55e-17 Erythrocyte sedimentation rate; LIHC cis rs734999 0.545 rs12730932 chr1:2559589 T/G cg18854424 chr1:2615690 NA -0.33 -7.23 -0.36 3.22e-12 Ulcerative colitis; LIHC cis rs7659604 0.540 rs4833775 chr4:122716826 T/C cg19671926 chr4:122722719 EXOSC9 0.57 8.71 0.43 1.31e-16 Type 2 diabetes; LIHC cis rs72781680 0.898 rs72780121 chr2:23995918 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs7520050 0.966 rs6429582 chr1:46321843 C/T cg03146154 chr1:46216737 IPP 0.36 5.88 0.3 9.63e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2832191 0.967 rs1999321 chr21:30530233 A/C cg08807101 chr21:30365312 RNF160 0.54 8.38 0.41 1.38e-15 Dental caries; LIHC cis rs4819052 0.851 rs13050359 chr21:46672671 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.73 0.54 6.22e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11764590 0.666 rs7787359 chr7:2090849 A/G cg23422044 chr7:1970798 MAD1L1 -0.56 -8.76 -0.43 8.91e-17 Neuroticism; LIHC trans rs17685 0.753 rs1639609 chr7:75683581 T/C cg19862616 chr7:65841803 NCRNA00174 0.92 19.02 0.72 1.56e-55 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17776563 0.959 rs11857151 chr15:89112877 C/G cg05013243 chr15:89149849 MIR1179 0.45 7.57 0.38 3.55e-13 Thyroid hormone levels; LIHC cis rs929354 0.772 rs10228145 chr7:157007337 A/G cg16102536 chr7:156981717 UBE3C 0.36 6.11 0.31 2.72e-9 Body mass index; LIHC cis rs2274273 0.840 rs28493647 chr14:55824463 T/C cg01864836 chr14:55583639 NA -0.37 -6.62 -0.34 1.36e-10 Protein biomarker; LIHC cis rs3204270 0.714 rs8074828 chr17:79657136 G/C cg18367735 chr17:79674897 NA 0.7 8.33 0.41 1.98e-15 Dental caries; LIHC cis rs61774743 0.681 rs10889959 chr1:41849735 T/C cg08462924 chr1:41848221 NA 0.35 5.94 0.31 6.83e-9 Intelligence (multi-trait analysis); LIHC cis rs9394841 0.536 rs6899876 chr6:41796970 A/G cg08135965 chr6:41755394 TOMM6 0.43 5.84 0.3 1.2e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs896854 0.714 rs572547 chr8:95966286 A/G cg09323728 chr8:95962352 TP53INP1 0.32 6.22 0.32 1.43e-9 Type 2 diabetes; LIHC cis rs12950390 0.853 rs17700008 chr17:45863591 A/C cg03474202 chr17:45855739 NA 0.32 5.72 0.3 2.35e-8 IgG glycosylation; LIHC cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.77 -0.69 1.69e-50 Gut microbiome composition (summer); LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.47 -6.77 -0.34 5.6e-11 Lymphocyte counts; LIHC cis rs597539 0.652 rs674654 chr11:68698762 G/T cg06028808 chr11:68637592 NA 0.45 5.8 0.3 1.47e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg18357526 chr6:26021779 HIST1H4A 1.05 15.45 0.64 3.09e-41 Intelligence (multi-trait analysis); LIHC cis rs1728785 1.000 rs7196104 chr16:68579746 C/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs2274273 1.000 rs61508494 chr14:55587297 T/C cg01864836 chr14:55583639 NA -0.36 -6.59 -0.34 1.64e-10 Protein biomarker; LIHC cis rs11098499 0.564 rs11098507 chr4:120288286 G/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs9457247 0.905 rs453184 chr6:167387404 A/C cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs2273156 1.000 rs7145608 chr14:35463497 G/T cg16230307 chr14:35515116 FAM177A1 -0.41 -6.04 -0.31 3.96e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs2180341 0.960 rs7745944 chr6:127709574 A/G cg27446573 chr6:127587934 RNF146 1.03 16.27 0.66 1.75e-44 Breast cancer; LIHC cis rs17106184 0.892 rs57254915 chr1:51139001 G/T cg07174182 chr1:51127561 FAF1 -0.76 -8.12 -0.4 8.47e-15 Type 2 diabetes; LIHC cis rs2295359 1.000 rs4655682 chr1:67610967 C/T cg12940439 chr1:67600707 NA 0.39 7.14 0.36 5.72e-12 Psoriasis; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02926110 chr15:72411069 MYO9A;SENP8 -0.41 -6.12 -0.31 2.62e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs765787 0.530 rs2554455 chr15:45521304 T/C cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.7e-10 Uric acid levels; LIHC cis rs4409675 0.619 rs12070173 chr1:28231955 G/C cg23691781 chr1:28212827 C1orf38 0.3 7.34 0.37 1.54e-12 Corneal astigmatism; LIHC cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.61 0.46 1.69e-19 Electroencephalogram traits; LIHC cis rs875971 1.000 rs10257427 chr7:65743208 T/C cg18876405 chr7:65276391 NA -0.37 -6.73 -0.34 7.14e-11 Aortic root size; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg18306943 chr3:40428807 ENTPD3 0.41 7.34 0.37 1.58e-12 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg09455208 chr3:40491958 NA 0.4 8.25 0.41 3.44e-15 Renal cell carcinoma; LIHC cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg14393609 chr7:65229607 NA 0.44 6.55 0.33 2.08e-10 Calcium levels; LIHC cis rs3748682 0.731 rs9729719 chr1:38298207 G/A cg12658694 chr1:38397304 INPP5B 0.42 5.72 0.3 2.29e-8 Hypothyroidism; LIHC cis rs6831352 0.918 rs13113166 chr4:100050528 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7927592 0.731 rs7108376 chr11:68347870 A/G cg20283391 chr11:68216788 NA 0.38 6.05 0.31 3.85e-9 Total body bone mineral density; LIHC cis rs4563143 0.514 rs73029081 chr19:29295583 C/G cg14983838 chr19:29218262 NA 0.44 6.41 0.33 4.83e-10 Methadone dose in opioid dependence; LIHC cis rs4891159 0.790 rs7237974 chr18:74108860 A/G cg24786174 chr18:74118243 ZNF516 -0.78 -13.83 -0.6 7.18e-35 Longevity; LIHC cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.29 0.52 2.51e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7940866 0.874 rs1433979 chr11:130871617 G/A cg12179176 chr11:130786555 SNX19 0.53 7.48 0.38 6.23e-13 Schizophrenia; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.5 -7.14 -0.36 5.48e-12 Lymphocyte counts; LIHC trans rs11098499 0.954 rs7654587 chr4:120388406 C/T cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs11031096 0.655 rs10835734 chr11:4211832 A/C cg18678763 chr11:4115507 RRM1 -0.41 -5.92 -0.3 7.73e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2230307 0.536 rs522696 chr1:100476662 G/A cg24955406 chr1:100503596 HIAT1 0.62 6.2 0.32 1.62e-9 Carotid intima media thickness; LIHC cis rs7000551 0.751 rs1482337 chr8:22395509 A/G cg12081754 chr8:22256438 SLC39A14 -0.44 -7.21 -0.36 3.65e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs8044995 0.563 rs3785113 chr16:68369213 T/C cg09835421 chr16:68378352 PRMT7 -0.83 -10.03 -0.48 6.35e-21 Schizophrenia; LIHC cis rs4474465 1.000 rs2063728 chr11:78185636 G/C cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg03517284 chr6:25882590 NA -0.58 -7.33 -0.37 1.72e-12 Intelligence (multi-trait analysis); LIHC cis rs10924970 0.649 rs1933247 chr1:235432767 A/G cg26050004 chr1:235667680 B3GALNT2 0.4 5.73 0.3 2.15e-8 Asthma; LIHC cis rs5769765 0.825 rs7511620 chr22:50307932 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.56 -0.5 9.29e-23 Schizophrenia; LIHC cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg14393609 chr7:65229607 NA 0.44 6.54 0.33 2.18e-10 Aortic root size; LIHC cis rs2304206 0.614 rs12104272 chr19:50148052 A/G cg09250473 chr19:50168907 IRF3;BCL2L12 -0.61 -8.38 -0.41 1.39e-15 Vitiligo; LIHC cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs7572733 0.555 rs7420608 chr2:198915930 A/T cg10820045 chr2:198174542 NA 0.41 6.2 0.32 1.67e-9 Dermatomyositis; LIHC cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg23205692 chr1:25664452 TMEM50A 0.38 6.11 0.31 2.65e-9 Erythrocyte sedimentation rate; LIHC cis rs7772486 0.875 rs6913797 chr6:146413758 A/G cg23711669 chr6:146136114 FBXO30 0.58 10.0 0.48 7.94e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs769267 0.930 rs10282 chr19:19619317 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.5 7.6 0.38 2.93e-13 Tonsillectomy; LIHC cis rs6545883 0.965 rs7421663 chr2:61753786 C/T cg15711740 chr2:61764176 XPO1 -0.44 -6.16 -0.32 2.01e-9 Tuberculosis; LIHC cis rs6062302 0.522 rs13043255 chr20:62218916 C/G cg16989086 chr20:62203971 PRIC285 0.51 7.31 0.37 1.86e-12 Glioblastoma; LIHC trans rs465757 1.000 rs465757 chr20:15580283 A/G cg12283520 chr1:27989987 NA -0.45 -6.31 -0.32 8.7e-10 Interleukin-10 levels; LIHC cis rs6598955 0.543 rs57564009 chr1:26557618 A/T cg04990556 chr1:26633338 UBXN11 0.76 11.15 0.52 7.94e-25 Obesity-related traits; LIHC cis rs9993613 0.935 rs11942991 chr4:73524203 T/C cg15102770 chr4:73434591 ADAMTS3 -0.38 -5.74 -0.3 2.05e-8 Hip circumference adjusted for BMI;Height; LIHC cis rs1707322 1.000 rs10890360 chr1:46338444 C/T cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1355223 0.902 rs836466 chr11:34737366 G/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs12711979 0.765 rs7559461 chr2:3818623 G/A cg17052675 chr2:3827356 NA -0.42 -7.28 -0.37 2.35e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs9814567 0.964 rs6772406 chr3:134210183 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.07e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25887850 chr20:44509743 ZSWIM1 0.43 6.53 0.33 2.36e-10 Cognitive function; LIHC cis rs916888 0.821 rs199509 chr17:44858728 G/A cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs16828019 0.704 rs34486565 chr1:41522510 C/T cg20697417 chr1:41786797 NA 0.31 5.82 0.3 1.35e-8 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.800 rs11869259 chr17:37518141 C/A cg00129232 chr17:37814104 STARD3 0.38 6.15 0.32 2.21e-9 Glomerular filtration rate (creatinine); LIHC cis rs950169 0.922 rs62021167 chr15:85118051 T/A cg03959625 chr15:84868606 LOC388152 0.43 5.84 0.3 1.22e-8 Schizophrenia; LIHC cis rs13256369 1.000 rs4841017 chr8:8577093 A/G cg00074818 chr8:8560427 CLDN23 0.37 6.15 0.32 2.21e-9 Obesity-related traits; LIHC cis rs9467773 1.000 rs9467797 chr6:26568473 A/T cg09904177 chr6:26538194 HMGN4 0.66 13.75 0.6 1.5e-34 Intelligence (multi-trait analysis); LIHC cis rs8060686 0.623 rs7201591 chr16:68086105 A/G cg05110241 chr16:68378359 PRMT7 -0.53 -6.37 -0.33 5.95e-10 HDL cholesterol;Metabolic syndrome; LIHC trans rs8073060 0.586 rs225294 chr17:33925762 G/A cg19694781 chr19:47549865 TMEM160 -1.23 -12.78 -0.57 7.71e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9911578 0.900 rs4793593 chr17:56892699 C/G cg05425664 chr17:57184151 TRIM37 0.59 8.85 0.43 4.78e-17 Intelligence (multi-trait analysis); LIHC cis rs1559088 0.739 rs9304845 chr19:33592794 A/G cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs10489202 0.634 rs6427119 chr1:168074145 A/G cg24449463 chr1:168025552 DCAF6 0.48 6.7 0.34 8.45e-11 Schizophrenia; LIHC cis rs1797081 0.646 rs7090256 chr10:16851949 T/G cg23933602 chr10:16859644 RSU1 0.59 9.12 0.44 6.48e-18 Platelet distribution width; LIHC cis rs7129220 0.588 rs61878631 chr11:10134832 C/T cg01453529 chr11:10209919 SBF2 -0.38 -6.8 -0.35 4.72e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs8078723 1.000 rs4795418 chr17:38164851 T/C cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.14 -0.44 5.58e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9318086 0.935 rs2025701 chr13:24440581 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.54 10.86 0.51 8.57e-24 Myopia (pathological); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23018242 chr22:31608245 LIMK2 -0.43 -6.35 -0.32 6.81e-10 Cognitive function; LIHC cis rs3106136 0.967 rs11722476 chr4:95170839 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.93 -0.39 3.1e-14 Capecitabine sensitivity; LIHC cis rs4700695 0.719 rs27085 chr5:65435063 C/T cg21114390 chr5:65439923 SFRS12 0.6 8.67 0.42 1.77e-16 Facial morphology (factor 19); LIHC cis rs74233809 1.000 rs79993475 chr10:104901031 A/G cg03493300 chr10:104813866 CNNM2 0.47 6.26 0.32 1.13e-9 Birth weight; LIHC cis rs2404602 0.608 rs12439484 chr15:76602937 A/C cg23625390 chr15:77176239 SCAPER 0.35 6.04 0.31 4.02e-9 Blood metabolite levels; LIHC cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg18252515 chr7:66147081 NA 1.29 17.25 0.68 2.03e-48 Diabetic kidney disease; LIHC cis rs6466055 0.739 rs10953474 chr7:104923005 A/G cg04380332 chr7:105027541 SRPK2 0.37 6.86 0.35 3.2e-11 Schizophrenia; LIHC cis rs10420951 0.617 rs79888481 chr19:18569957 G/A cg10790698 chr19:18539756 SSBP4 -0.42 -5.93 -0.31 7.23e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2836974 0.644 rs9978775 chr21:40694526 A/G cg11890956 chr21:40555474 PSMG1 -0.46 -7.24 -0.36 2.94e-12 Cognitive function; LIHC cis rs2439831 1.000 rs2439831 chr15:43784475 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 13.96 0.6 2.37e-35 Lung cancer in ever smokers; LIHC cis rs2180341 0.814 rs7768435 chr6:127737038 A/C cg24812749 chr6:127587940 RNF146 0.79 12.59 0.56 4.04e-30 Breast cancer; LIHC cis rs12594515 1.000 rs8038058 chr15:45990272 C/T cg01629716 chr15:45996671 NA 0.52 9.49 0.46 4.11e-19 Waist circumference;Weight; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27614445 chr3:179041226 ZNF639 0.58 7.55 0.38 4.03e-13 Lung function (FEV1/FVC); LIHC cis rs8077889 0.719 rs4793033 chr17:41879627 C/T cg26893861 chr17:41843967 DUSP3 0.96 15.99 0.65 2.39e-43 Triglycerides; LIHC cis rs9902453 0.845 rs2617865 chr17:28049804 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -11.78 -0.54 4.04e-27 Coffee consumption (cups per day); LIHC cis rs1008375 0.966 rs10489036 chr4:17697687 A/G cg16339924 chr4:17578868 LAP3 0.44 5.71 0.3 2.45e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2455799 0.613 rs13080145 chr3:15880060 C/G cg12698662 chr3:15914712 MIR563 -0.4 -7.32 -0.37 1.79e-12 Mean platelet volume; LIHC cis rs12980942 0.810 rs12974323 chr19:41807071 A/G cg25627403 chr19:41769009 HNRNPUL1 0.49 6.18 0.32 1.8e-9 Coronary artery disease; LIHC cis rs9303401 0.614 rs12950028 chr17:56510140 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.84 10.94 0.51 4.43e-24 Cognitive test performance; LIHC cis rs6918586 0.658 rs198837 chr6:26113398 A/T cg18357526 chr6:26021779 HIST1H4A 0.56 8.22 0.41 4.23e-15 Schizophrenia; LIHC cis rs1552244 0.882 rs67631672 chr3:10004768 G/A cg00149659 chr3:10157352 C3orf10 0.5 5.81 0.3 1.45e-8 Alzheimer's disease; LIHC cis rs801193 1.000 rs4717319 chr7:66242593 A/G cg18876405 chr7:65276391 NA 0.43 7.4 0.37 1.06e-12 Aortic root size; LIHC cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg02931644 chr1:25747376 RHCE 0.34 7.42 0.37 9.5e-13 Plateletcrit;Mean corpuscular volume; LIHC cis rs11122272 0.735 rs2486733 chr1:231531465 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs2421770 0.504 rs4756213 chr11:35363566 T/C cg13971030 chr11:35366721 SLC1A2 -0.43 -7.29 -0.37 2.11e-12 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg22903471 chr2:27725779 GCKR -0.52 -8.97 -0.44 1.93e-17 Total body bone mineral density; LIHC cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg11764359 chr7:65958608 NA 0.69 9.38 0.45 9.59e-19 Calcium levels; LIHC cis rs7772486 0.790 rs3924499 chr6:146232978 A/T cg23711669 chr6:146136114 FBXO30 -0.7 -12.25 -0.55 7.23e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs116248771 0.549 rs1548013 chr3:158431070 C/T cg16708174 chr3:158430962 RARRES1 0.76 9.78 0.47 4.54e-20 diarrhoeal disease at age 2; LIHC cis rs13161895 1.000 rs17079968 chr5:179443423 C/T cg02702477 chr5:179499311 RNF130 0.75 10.33 0.49 5.85e-22 LDL cholesterol; LIHC cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg22800045 chr5:56110881 MAP3K1 0.67 8.65 0.42 2.06e-16 Initial pursuit acceleration; LIHC cis rs12530845 0.673 rs4269479 chr7:135332379 C/T cg23117316 chr7:135346802 PL-5283 -0.4 -5.96 -0.31 6.35e-9 Red blood cell traits; LIHC cis rs6952407 1 rs6952407 chr7:66045512 A/G cg14393609 chr7:65229607 NA -0.43 -6.47 -0.33 3.47e-10 Cotinine glucuronidation; LIHC cis rs9814567 0.964 rs4539979 chr3:134287597 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -6.01 -0.31 4.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg19774624 chr17:42201019 HDAC5 -0.82 -12.82 -0.57 5.62e-31 Total body bone mineral density; LIHC cis rs1538970 1.000 rs17395553 chr1:45864761 C/T cg24296786 chr1:45957014 TESK2 -0.5 -7.38 -0.37 1.23e-12 Platelet count; LIHC cis rs12579753 1.000 rs11115047 chr12:82232773 C/G cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs9303401 0.921 rs34102441 chr17:56877414 A/G cg25039879 chr17:56429692 SUPT4H1 0.53 7.35 0.37 1.44e-12 Cognitive test performance; LIHC cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg20607798 chr8:58055168 NA 0.53 6.63 0.34 1.27e-10 Developmental language disorder (linguistic errors); LIHC cis rs2115630 0.691 rs61322921 chr15:85163638 T/C cg11189052 chr15:85197271 WDR73 -0.51 -7.86 -0.39 5.14e-14 P wave terminal force; LIHC cis rs6964587 0.967 rs41371748 chr7:91708219 A/G cg17063962 chr7:91808500 NA 0.94 14.44 0.62 3.01e-37 Breast cancer; LIHC cis rs1707322 0.963 rs4553121 chr1:46375253 G/A cg06784218 chr1:46089804 CCDC17 0.34 6.09 0.31 3.11e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg18306943 chr3:40428807 ENTPD3 -0.44 -7.81 -0.39 6.94e-14 Renal cell carcinoma; LIHC cis rs6815814 0.861 rs10004195 chr4:38784724 T/A cg06935464 chr4:38784597 TLR10 0.54 9.53 0.46 2.96e-19 Breast cancer; LIHC cis rs78456975 0.527 rs11886696 chr2:1567841 A/G cg01028140 chr2:1542097 TPO -0.42 -6.67 -0.34 1.01e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs67460515 0.563 rs16831981 chr3:160897780 T/C cg03342759 chr3:160939853 NMD3 -0.61 -9.22 -0.45 3.01e-18 Parkinson's disease; LIHC cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg20295408 chr7:1910781 MAD1L1 -0.43 -6.26 -0.32 1.15e-9 Bipolar disorder and schizophrenia; LIHC cis rs7582720 1.000 rs79642273 chr2:203830851 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7572733 0.555 rs7600269 chr2:198923468 C/G cg00792783 chr2:198669748 PLCL1 0.42 5.99 0.31 5.44e-9 Dermatomyositis; LIHC cis rs9916302 0.861 rs593480 chr17:37453780 A/C cg07936489 chr17:37558343 FBXL20 0.83 13.64 0.59 4.07e-34 Glomerular filtration rate (creatinine); LIHC cis rs881375 0.678 rs7037195 chr9:123684000 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.42 6.16 0.32 2.02e-9 Rheumatoid arthritis; LIHC cis rs1789 0.903 rs4453929 chr4:15672173 T/G cg16509355 chr4:15471240 CC2D2A -0.46 -7.02 -0.35 1.23e-11 Blood protein levels; LIHC cis rs5753618 0.509 rs2413033 chr22:31574213 A/G cg07713946 chr22:31675144 LIMK2 -0.41 -7.4 -0.37 1.04e-12 Colorectal cancer; LIHC cis rs600806 0.778 rs10857787 chr1:110010289 C/T cg10127483 chr1:110009974 SYPL2 0.46 5.95 0.31 6.76e-9 Intelligence (multi-trait analysis); LIHC cis rs17253792 0.732 rs8017891 chr14:56172967 A/G cg01858014 chr14:56050164 KTN1 0.59 6.56 0.33 2.02e-10 Putamen volume; LIHC cis rs769267 0.930 rs747050 chr19:19584987 C/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.04 0.31 4.13e-9 Tonsillectomy; LIHC cis rs7659604 0.676 rs4516739 chr4:122699741 G/T cg19748678 chr4:122722346 EXOSC9 0.65 10.48 0.49 1.82e-22 Type 2 diabetes; LIHC cis rs9522267 0.535 rs7329118 chr13:112232693 C/T cg10483660 chr13:112241077 NA -0.22 -5.88 -0.3 9.86e-9 Hepatitis; LIHC cis rs523522 0.962 rs2168319 chr12:120933217 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.98 0.54 7.32e-28 High light scatter reticulocyte count; LIHC cis rs4845459 0.967 rs9633406 chr1:152591446 C/G cg20634798 chr1:152595351 LCE3A -0.31 -5.92 -0.3 7.88e-9 Psoriasis; LIHC cis rs4908768 0.871 rs7553298 chr1:8770883 A/G cg25722041 chr1:8623473 RERE 0.42 6.2 0.32 1.63e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1005277 0.579 rs2474588 chr10:38420870 A/G cg25427524 chr10:38739819 LOC399744 -0.64 -12.28 -0.55 5.86e-29 Extrinsic epigenetic age acceleration; LIHC cis rs2070488 0.965 rs2284819 chr3:38557161 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.84 13.53 0.59 1.08e-33 Electrocardiographic conduction measures; LIHC cis rs2197308 0.655 rs1971964 chr12:37870474 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs7589728 0.563 rs78685993 chr2:88447026 T/C cg14558114 chr2:88469736 THNSL2 0.59 5.72 0.3 2.3e-8 Plasma clusterin levels; LIHC cis rs1198430 1.000 rs1198431 chr1:23755716 C/T cg19827787 chr1:23763612 ASAP3 -0.36 -6.43 -0.33 4.31e-10 Total cholesterol levels; LIHC cis rs28595532 0.623 rs34531766 chr4:119230339 T/C cg21605333 chr4:119757512 SEC24D 0.8 6.82 0.35 4.23e-11 Cannabis dependence symptom count; LIHC cis rs12611088 0.600 rs2682553 chr19:44004566 A/G cg13740135 chr19:44006432 PHLDB3 -0.43 -6.29 -0.32 9.78e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs16854884 0.632 rs34071449 chr3:143662861 C/T cg06585982 chr3:143692056 C3orf58 0.58 7.69 0.38 1.5700000000000001e-13 Economic and political preferences (feminism/equality); LIHC cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.75e-9 Menopause (age at onset); LIHC cis rs2000999 0.515 rs2854956 chr16:72115238 A/T cg01557791 chr16:72042693 DHODH -0.51 -8.11 -0.4 9.28e-15 Total cholesterol levels;Cholesterol, total;Blood protein levels;LDL cholesterol levels;Haptoglobin levels;LDL cholesterol; LIHC cis rs2834188 0.924 rs2409487 chr21:34684958 C/T cg14352951 chr21:34696688 IFNAR1 0.46 6.39 0.33 5.42e-10 Narcolepsy; LIHC cis rs7647973 1.000 rs1009051 chr3:49521549 G/A cg07636037 chr3:49044803 WDR6 0.51 6.48 0.33 3.25e-10 Menarche (age at onset); LIHC cis rs2197308 0.765 rs117216293 chr12:37882982 T/C cg26384229 chr12:38710491 ALG10B -0.47 -6.53 -0.33 2.39e-10 Morning vs. evening chronotype; LIHC cis rs35110281 0.805 rs4818843 chr21:45006607 C/T cg04455712 chr21:45112962 RRP1B 0.44 7.38 0.37 1.19e-12 Mean corpuscular volume; LIHC cis rs2635047 0.565 rs2668759 chr18:44693711 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.42 6.05 0.31 3.8e-9 Educational attainment; LIHC cis rs9457247 0.602 rs4710175 chr6:167467800 A/G cg23791538 chr6:167370224 RNASET2 -0.53 -7.8 -0.39 7.69e-14 Crohn's disease; LIHC cis rs2120019 1.000 rs34655806 chr15:75362586 T/C cg17294928 chr15:75287854 SCAMP5 -0.5 -7.55 -0.38 4.07e-13 Blood trace element (Zn levels); LIHC cis rs9378688 0.654 rs2505662 chr6:2326185 T/C cg12303981 chr6:2244766 GMDS -0.45 -6.06 -0.31 3.59e-9 Caudate nucleus volume; LIHC cis rs4819052 0.788 rs35323494 chr21:46703739 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.64 9.06 0.44 1.01e-17 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5769765 0.862 rs9616385 chr22:50313124 C/T cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg23131131 chr22:24373011 LOC391322 -0.65 -9.72 -0.47 7.17e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7786877 0.508 rs11765509 chr7:100310990 T/G cg20848291 chr7:100343083 ZAN -0.51 -7.23 -0.36 3.25e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9948 0.655 rs62156213 chr2:97399100 T/C cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7647973 0.677 rs11130211 chr3:49645209 C/T cg03060546 chr3:49711283 APEH 0.61 6.88 0.35 2.89e-11 Menarche (age at onset); LIHC cis rs2777491 0.915 rs8036498 chr15:41603276 A/G cg18705301 chr15:41695430 NDUFAF1 -0.56 -8.28 -0.41 2.89e-15 Ulcerative colitis; LIHC cis rs12497850 0.897 rs6781790 chr3:49044767 C/T cg06212747 chr3:49208901 KLHDC8B 0.58 7.58 0.38 3.34e-13 Parkinson's disease; LIHC cis rs61440199 0.818 rs11917197 chr3:20181393 C/T cg00235661 chr3:20228976 SGOL1 -0.42 -5.77 -0.3 1.74e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs60871478 1.000 rs35488064 chr7:812722 G/C cg04727924 chr7:799746 HEATR2 -0.59 -8.65 -0.42 2.01e-16 Cerebrospinal P-tau181p levels; LIHC cis rs6500602 0.727 rs11076836 chr16:4569331 G/A cg08645402 chr16:4508243 NA 0.44 8.25 0.41 3.56e-15 Schizophrenia; LIHC cis rs2976388 0.647 rs2572906 chr8:143798269 G/A cg06565975 chr8:143823917 SLURP1 0.33 6.16 0.32 2.07e-9 Urinary tract infection frequency; LIHC cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg03188948 chr7:1209495 NA 0.8 5.94 0.31 6.83e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.36 0.45 1.07e-18 Bipolar disorder; LIHC cis rs3806843 1.000 rs6579987 chr5:140183659 T/C cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4919694 1.000 rs11191490 chr10:104745174 T/A cg04362960 chr10:104952993 NT5C2 1.13 8.79 0.43 7.28e-17 Arsenic metabolism; LIHC cis rs782590 0.807 rs782642 chr2:55928444 G/T cg03859395 chr2:55845619 SMEK2 0.88 14.91 0.63 4.44e-39 Metabolic syndrome; LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg06656553 chr16:89960601 TCF25 -0.48 -5.93 -0.31 7.6e-9 Skin colour saturation; LIHC cis rs9467773 1.000 rs3736782 chr6:26505403 C/A cg09904177 chr6:26538194 HMGN4 0.66 13.85 0.6 6.03e-35 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.954 rs13133522 chr4:120324424 A/T cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs7917772 0.505 rs61869211 chr10:104449836 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.58 7.01 0.35 1.28e-11 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg03264133 chr6:25882463 NA 0.49 6.16 0.32 2.03e-9 Intelligence (multi-trait analysis); LIHC cis rs11585357 0.947 rs2977303 chr1:17611548 A/T cg08277548 chr1:17600880 PADI3 -0.53 -6.29 -0.32 9.93e-10 Hair shape; LIHC cis rs12950390 0.853 rs11655112 chr17:45856563 T/C cg03474202 chr17:45855739 NA -0.35 -5.99 -0.31 5.39e-9 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12868349 chr11:71639594 RNF121;LOC100133315 0.47 6.37 0.33 6.1e-10 Pancreatic cancer; LIHC cis rs4820294 0.669 rs7287340 chr22:38054325 C/T cg10587741 chr22:38071170 LGALS1 0.44 7.93 0.39 3.22e-14 Fat distribution (HIV); LIHC cis rs1941023 0.584 rs10897057 chr11:60172273 A/T cg08716584 chr11:60157161 MS4A7 -0.36 -8.25 -0.41 3.45e-15 Congenital heart disease (maternal effect); LIHC trans rs9747201 0.962 rs62078313 chr17:80116708 A/C cg07393940 chr7:158741817 NA -0.57 -6.94 -0.35 1.92e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11671005 0.779 rs35631681 chr19:58999840 C/T cg25952890 chr19:58913133 NA 0.73 7.57 0.38 3.39e-13 Mean platelet volume; LIHC cis rs727505 1.000 rs56356267 chr7:124557549 A/G cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.22e-9 Lewy body disease; LIHC cis rs11764590 0.671 rs12669370 chr7:2081914 G/A cg23422044 chr7:1970798 MAD1L1 -0.46 -7.05 -0.36 9.83e-12 Neuroticism; LIHC cis rs637571 0.546 rs10791827 chr11:65596546 C/A cg26695010 chr11:65641043 EFEMP2 0.47 6.7 0.34 8.35e-11 Eosinophil percentage of white cells; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.89 -0.3 9.34e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg23758822 chr17:41437982 NA 0.92 17.07 0.68 1.09e-47 Menopause (age at onset); LIHC cis rs8032158 1.000 rs8032158 chr15:56194877 T/C cg24530489 chr15:56299380 NA 0.43 6.01 0.31 4.81e-9 Keloid; LIHC cis rs655641 1.000 rs592297 chr11:85725937 C/T cg09030501 chr11:85779252 PICALM -0.52 -6.14 -0.32 2.26e-9 Platelet count; LIHC cis rs1461503 0.932 rs10790542 chr11:122838243 C/T cg14473756 chr11:122847823 NA -0.37 -6.65 -0.34 1.18e-10 Menarche (age at onset); LIHC cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.82 8.66 0.42 1.93e-16 Platelet count; LIHC cis rs7116495 0.881 rs1783959 chr11:71595981 T/C cg26138937 chr11:71823887 C11orf51 0.7 7.07 0.36 8.59e-12 Severe influenza A (H1N1) infection; LIHC cis rs611744 0.647 rs7015240 chr8:109262204 G/A cg21045802 chr8:109455806 TTC35 0.58 10.27 0.49 9.39e-22 Dupuytren's disease; LIHC cis rs7512552 0.839 rs3820544 chr1:150457876 A/T cg15654264 chr1:150340011 RPRD2 0.69 11.17 0.52 6.72e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21537245 chr1:20960434 PINK1 -0.57 -6.76 -0.34 5.9e-11 Systolic blood pressure; LIHC cis rs35110281 0.774 rs2838323 chr21:44999086 G/A cg21573476 chr21:45109991 RRP1B -0.53 -9.84 -0.47 2.83e-20 Mean corpuscular volume; LIHC cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg00149659 chr3:10157352 C3orf10 0.68 7.2 0.36 3.97e-12 Alzheimer's disease; LIHC cis rs9905704 0.647 rs12944274 chr17:57041293 C/G cg12560992 chr17:57184187 TRIM37 -0.66 -9.7 -0.46 8.22e-20 Testicular germ cell tumor; LIHC cis rs2050392 0.789 rs303438 chr10:30733493 C/T cg25182066 chr10:30743637 MAP3K8 0.5 7.96 0.4 2.53e-14 Inflammatory bowel disease; LIHC cis rs4888262 0.526 rs12921903 chr16:74625575 C/T cg01733217 chr16:74700730 RFWD3 0.83 16.02 0.65 1.79e-43 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs7747306 chr6:8453663 C/G cg21535247 chr6:8435926 SLC35B3 -0.62 -8.17 -0.4 5.86e-15 Motion sickness; LIHC cis rs7512552 0.839 rs2794684 chr1:150320571 C/T cg15654264 chr1:150340011 RPRD2 0.7 11.58 0.53 2.26e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9303280 0.936 rs907091 chr17:37921742 A/G cg11212589 chr17:38028394 ZPBP2 0.29 6.1 0.31 2.89e-9 Self-reported allergy; LIHC cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.54 -8.28 -0.41 2.86e-15 Menarche (age at onset); LIHC cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.88 0.3 9.84e-9 Aortic root size; LIHC cis rs7959452 0.718 rs10878963 chr12:69717166 T/G cg14784868 chr12:69753453 YEATS4 0.64 10.51 0.49 1.4e-22 Blood protein levels; LIHC cis rs7772486 0.686 rs9376956 chr6:145949844 T/C cg23711669 chr6:146136114 FBXO30 0.63 11.52 0.53 3.73e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10947003 chr16:67218230 KIAA0895L 0.47 6.95 0.35 1.85e-11 Cognitive function; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04816434 chr15:22945077 CYFIP1 0.41 6.06 0.31 3.51e-9 Longevity; LIHC cis rs2153535 0.580 rs7743995 chr6:8496212 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.78 0.54 4.09e-27 Motion sickness; LIHC cis rs67478160 0.609 rs6576003 chr14:104291330 C/A cg01849466 chr14:104193079 ZFYVE21 -0.49 -8.34 -0.41 1.81e-15 Schizophrenia; LIHC cis rs965469 0.779 rs6051761 chr20:3321568 A/G cg25506879 chr20:3388711 C20orf194 0.51 6.22 0.32 1.45e-9 IFN-related cytopenia; LIHC cis rs7116495 0.609 rs60054591 chr11:71825687 G/A cg26138937 chr11:71823887 C11orf51 1.32 10.9 0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC trans rs3783890 1.000 rs12587394 chr14:93754437 A/G cg02802420 chr16:69363236 PDF;COG8 0.32 6.24 0.32 1.29e-9 Body mass index; LIHC cis rs459571 0.635 rs379471 chr9:136890649 G/A cg13789015 chr9:136890014 NCRNA00094 0.46 8.33 0.41 2.04e-15 Platelet distribution width; LIHC cis rs986417 0.818 rs8014133 chr14:61104738 A/G cg27398547 chr14:60952738 C14orf39 0.65 7.25 0.37 2.77e-12 Gut microbiota (bacterial taxa); LIHC cis rs11628318 0.614 rs72635192 chr14:103128646 C/T cg01864069 chr14:103024347 NA 0.45 6.98 0.35 1.51e-11 Platelet count; LIHC cis rs12744310 0.887 rs12728217 chr1:41798269 C/T cg03962019 chr1:41807865 NA 0.38 6.18 0.32 1.78e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9614461 0.702 rs3788648 chr22:45727180 G/A cg00117651 chr22:45809523 SMC1B;RIBC2 0.52 5.9 0.3 8.69e-9 Tonsillectomy; LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg21003380 chr1:156261207 TMEM79 0.37 5.96 0.31 6.12e-9 Tonsillectomy; LIHC trans rs10506458 0.688 rs73127095 chr12:63418283 T/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.72 -10.61 -0.5 6.57e-23 Hemostatic factors and hematological phenotypes; LIHC trans rs3780486 0.846 rs10813950 chr9:33127640 A/G cg04842962 chr6:43655489 MRPS18A -1.03 -23.61 -0.79 8.66e-74 IgG glycosylation; LIHC cis rs2637266 1.000 rs12258924 chr10:78364758 G/A cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.17e-8 Pulmonary function; LIHC cis rs8177179 0.565 rs4355280 chr3:133468425 A/G cg24879335 chr3:133465180 TF 0.31 6.97 0.35 1.69e-11 Iron status biomarkers (transferrin levels); LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg18306943 chr3:40428807 ENTPD3 0.43 7.58 0.38 3.19e-13 Renal cell carcinoma; LIHC trans rs7193541 0.662 rs8052367 chr16:74658867 G/A cg23598604 chr1:99732472 LPPR4 -0.31 -6.47 -0.33 3.38e-10 Multiple myeloma; LIHC cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg10862848 chr6:42927986 GNMT -0.24 -5.81 -0.3 1.4e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs11122272 0.735 rs2295420 chr1:231485640 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -11.34 -0.52 1.68e-25 Hemoglobin concentration; LIHC cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg18252515 chr7:66147081 NA -1.25 -16.9 -0.67 5.3e-47 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16614638 chr11:34073070 CAPRIN1 0.51 7.06 0.36 9.21e-12 Lung function (FEV1/FVC); LIHC cis rs12893668 0.667 rs8017628 chr14:104047428 C/T cg24130564 chr14:104152367 KLC1 -0.54 -9.07 -0.44 9.8e-18 Reticulocyte count; LIHC cis rs3849570 0.925 rs13091492 chr3:81891476 A/G cg07356753 chr3:81810745 GBE1 -0.54 -8.55 -0.42 4.18e-16 Waist circumference;Body mass index; LIHC cis rs798554 0.796 rs2533884 chr7:2836848 T/G cg04166393 chr7:2884313 GNA12 0.46 6.19 0.32 1.74e-9 Height; LIHC cis rs8017423 0.967 rs4904662 chr14:90729427 G/A cg04374321 chr14:90722782 PSMC1 0.78 15.24 0.64 2.26e-40 Mortality in heart failure; LIHC cis rs10781543 0.845 rs35763810 chr9:139323799 A/G cg14169450 chr9:139327907 INPP5E 0.35 5.72 0.3 2.3e-8 Monocyte percentage of white cells; LIHC cis rs7903847 0.642 rs7909345 chr10:99150794 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.32 -0.32 8.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6582630 0.537 rs12823925 chr12:38409323 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.33 0.41 1.91e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs2645694 0.626 rs2703116 chr4:77824289 C/T cg06046430 chr4:77819534 ANKRD56 -0.49 -6.38 -0.33 5.68e-10 Emphysema distribution in smoking; LIHC cis rs12594515 1.000 rs58368732 chr15:45990531 G/C cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.17 -0.32 1.91e-9 Total body bone mineral density; LIHC cis rs11098499 0.657 rs9996569 chr4:120299004 G/C cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg15026243 chr5:465330 EXOC3 0.5 6.24 0.32 1.27e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14109799 chr14:31495427 AP4S1;STRN3 -0.44 -6.1 -0.31 2.89e-9 Pancreatic cancer; LIHC cis rs17685 0.753 rs1574107 chr7:75685047 A/C cg04592579 chr7:75616294 TMEM120A 0.41 7.02 0.35 1.22e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9326778 0.520 rs17673070 chr5:108833361 C/G cg17395555 chr5:108820864 NA -0.35 -5.93 -0.31 7.22e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs35110281 0.714 rs7277539 chr21:45053011 A/G cg21573476 chr21:45109991 RRP1B -0.57 -11.09 -0.51 1.27e-24 Mean corpuscular volume; LIHC cis rs6087771 0.504 rs6087786 chr20:30451844 C/T cg13852791 chr20:30311386 BCL2L1 0.6 6.04 0.31 3.93e-9 Subcortical brain region volumes;Putamen volume; LIHC cis rs8017423 0.967 rs4904657 chr14:90721600 A/G cg04374321 chr14:90722782 PSMC1 0.77 15.19 0.63 3.32e-40 Mortality in heart failure; LIHC cis rs2549003 1.000 rs2070731 chr5:131819798 T/C cg02551604 chr5:131831745 NA -0.47 -7.05 -0.36 9.66e-12 Asthma (sex interaction); LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg00815214 chr21:47717953 NA -0.36 -6.12 -0.31 2.57e-9 Testicular germ cell tumor; LIHC cis rs6840360 0.571 rs4696099 chr4:152501951 C/G cg22705602 chr4:152727874 NA -0.32 -6.26 -0.32 1.15e-9 Intelligence (multi-trait analysis); LIHC trans rs2243480 1.000 rs4718333 chr7:65772758 T/C cg10756647 chr7:56101905 PSPH -1.03 -12.6 -0.56 3.61e-30 Diabetic kidney disease; LIHC cis rs921968 0.565 rs1079177 chr2:219605929 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.9e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs892961 0.932 rs7207891 chr17:75413922 G/C cg01320579 chr17:75405842 SEPT9 0.54 7.72 0.39 1.26e-13 Airflow obstruction; LIHC trans rs1005277 0.579 rs1780122 chr10:38529509 C/A cg23533926 chr12:111358616 MYL2 -0.33 -6.33 -0.32 7.73e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2072499 0.778 rs41265025 chr1:156163906 C/T cg25208724 chr1:156163844 SLC25A44 0.71 8.08 0.4 1.1e-14 Testicular germ cell tumor; LIHC cis rs1144333 1.000 rs1586936 chr1:76366877 T/C cg22875332 chr1:76189707 ACADM 0.4 6.27 0.32 1.06e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2836974 0.666 rs4624474 chr21:40686327 T/C cg17971929 chr21:40555470 PSMG1 -0.44 -6.67 -0.34 1e-10 Cognitive function; LIHC cis rs1051424 0.642 rs115869798 chr17:57892829 T/A cg02344993 chr17:57696989 CLTC 0.72 12.37 0.56 2.76e-29 Obesity-related traits; LIHC cis rs936229 0.749 rs7497201 chr15:75190690 A/G cg14664628 chr15:75095509 CSK -0.72 -9.63 -0.46 1.44e-19 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs858239 0.508 rs10242104 chr7:23220450 C/T cg18081818 chr7:23246105 NA -0.41 -5.86 -0.3 1.06e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.65 9.59 0.46 1.9e-19 Lymphocyte counts; LIHC cis rs798554 0.757 rs1182178 chr7:2873763 G/A cg19346786 chr7:2764209 NA -0.45 -6.41 -0.33 4.93e-10 Height; LIHC cis rs12791968 1.000 rs1552300 chr11:45002594 G/A cg11846598 chr11:44996168 LOC221122 -0.44 -7.89 -0.39 4.26e-14 Inhibitory control; LIHC cis rs2153535 0.580 rs6597335 chr6:8527714 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.5 0.53 4.42e-26 Motion sickness; LIHC cis rs2066819 1.000 rs78121408 chr12:56684798 C/T cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs9888615 0.646 rs11624016 chr14:53384280 T/A cg00686598 chr14:53173677 PSMC6 -0.46 -6.17 -0.32 1.95e-9 Systolic blood pressure; LIHC cis rs2180341 0.722 rs9388555 chr6:127576363 G/A cg24812749 chr6:127587940 RNF146 0.74 10.83 0.51 1.08e-23 Breast cancer; LIHC cis rs1707322 0.655 rs3014240 chr1:46089225 C/G cg03146154 chr1:46216737 IPP -0.55 -9.17 -0.44 4.62e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg06453172 chr10:134556979 INPP5A -0.64 -7.82 -0.39 6.66e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs1814175 0.817 rs7932683 chr11:49983640 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs3540 0.533 rs1869179 chr15:90895564 A/C cg22089800 chr15:90895588 ZNF774 0.66 9.06 0.44 1.02e-17 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs919433 0.617 rs4850436 chr2:198541398 C/T cg03934865 chr2:198174659 NA -0.48 -6.93 -0.35 2.16e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7937682 0.824 rs577044 chr11:111490420 G/T cg09085632 chr11:111637200 PPP2R1B -0.89 -10.69 -0.5 3.2e-23 Primary sclerosing cholangitis; LIHC cis rs17685 0.712 rs9800948 chr7:75810473 A/G cg04610667 chr7:75704037 NA -0.34 -6.23 -0.32 1.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1997103 1.000 rs6973450 chr7:55396537 A/G cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg17178900 chr1:205818956 PM20D1 0.66 9.85 0.47 2.55e-20 Menarche (age at onset); LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.77 0.62 1.56e-38 Prudent dietary pattern; LIHC cis rs4689592 0.622 rs2276968 chr4:7070118 T/G cg26116260 chr4:7069785 GRPEL1 0.98 17.36 0.68 7.68e-49 Monocyte percentage of white cells; LIHC cis rs10751667 0.643 rs12278229 chr11:946985 A/G ch.11.42038R chr11:967971 AP2A2 0.53 9.4 0.45 8.28e-19 Alzheimer's disease (late onset); LIHC cis rs11663156 0.804 rs10515959 chr18:50893222 A/C cg24270629 chr18:50823537 DCC 0.52 7.1 0.36 7.37e-12 Intelligence (multi-trait analysis); LIHC cis rs965469 0.895 rs6051840 chr20:3391483 C/T cg25506879 chr20:3388711 C20orf194 0.56 6.57 0.33 1.84e-10 IFN-related cytopenia; LIHC cis rs2075371 1.000 rs2241334 chr7:133979225 C/G cg11752832 chr7:134001865 SLC35B4 0.51 7.82 0.39 6.75e-14 Mean platelet volume; LIHC cis rs6570726 0.791 rs6912079 chr6:145894949 G/A cg05347473 chr6:146136440 FBXO30 0.39 6.19 0.32 1.74e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.718 rs2694624 chr2:61672313 C/A cg14146966 chr2:61757674 XPO1 0.44 7.3 0.37 2.08e-12 Tuberculosis; LIHC cis rs12701220 0.553 rs13245507 chr7:1163694 C/T cg02733842 chr7:1102375 C7orf50 -0.68 -7.16 -0.36 4.83e-12 Bronchopulmonary dysplasia; LIHC cis rs6840360 0.571 rs4696273 chr4:152528477 G/A cg22705602 chr4:152727874 NA -0.33 -6.27 -0.32 1.08e-9 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.765 rs9457252 chr6:167433925 A/G cg07741184 chr6:167504864 NA -0.31 -7.38 -0.37 1.25e-12 Crohn's disease; LIHC cis rs8028182 0.537 rs4371118 chr15:75898890 C/A cg03649353 chr15:75614953 NA 0.43 6.49 0.33 3.06e-10 Sudden cardiac arrest; LIHC cis rs986417 1.000 rs4901995 chr14:61090629 C/G cg27398547 chr14:60952738 C14orf39 0.66 6.73 0.34 7.37e-11 Gut microbiota (bacterial taxa); LIHC cis rs1577917 0.916 rs12198730 chr6:86555138 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -11.19 -0.52 5.55e-25 Response to antipsychotic treatment; LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg02290350 chr8:58132656 NA 0.49 10.02 0.48 6.91e-21 Developmental language disorder (linguistic errors); LIHC cis rs34172651 0.917 rs200536 chr16:24749203 G/A cg00339695 chr16:24857497 SLC5A11 -0.55 -8.51 -0.42 5.59e-16 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.533 rs10839195 chr11:48973460 C/T cg15704280 chr7:45808275 SEPT13 -0.51 -7.7 -0.38 1.48e-13 Coronary artery disease; LIHC cis rs7542091 0.739 rs10863793 chr1:210037420 G/A cg22029157 chr1:209979665 IRF6 0.37 6.23 0.32 1.4e-9 Monobrow; LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg12016809 chr21:47604291 C21orf56 -0.47 -7.51 -0.38 5.09e-13 Testicular germ cell tumor; LIHC cis rs4423214 1.000 rs12807718 chr11:71171170 T/C cg24826892 chr11:71159390 DHCR7 0.47 6.12 0.31 2.55e-9 Vitamin D levels; LIHC cis rs4903214 0.848 rs34692843 chr14:74707535 T/C cg11132536 chr14:74711944 VSX2 -0.26 -5.75 -0.3 1.96e-8 Inflammatory bowel disease; LIHC cis rs8017423 0.967 rs12889636 chr14:90689953 A/C cg14092571 chr14:90743983 NA 0.4 6.29 0.32 9.48e-10 Mortality in heart failure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14416316 chr13:111145583 COL4A2 -0.42 -6.71 -0.34 8.19e-11 Lung function (FEV1/FVC); LIHC cis rs700651 0.752 rs1850631 chr2:198829468 T/G cg10820045 chr2:198174542 NA 0.49 7.49 0.38 5.81e-13 Intracranial aneurysm; LIHC cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg13409248 chr3:40428643 ENTPD3 0.41 6.91 0.35 2.41e-11 Renal cell carcinoma; LIHC cis rs875971 0.638 rs10249404 chr7:66046724 G/A cg18876405 chr7:65276391 NA -0.45 -7.89 -0.39 4.09e-14 Aortic root size; LIHC cis rs1552244 0.882 rs2030564 chr3:10039044 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs1577917 0.793 rs9362245 chr6:86496320 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.25 -0.36 2.81e-12 Response to antipsychotic treatment; LIHC cis rs1728785 1.000 rs698719 chr16:68560125 C/T cg02972257 chr16:68554789 NA -0.53 -6.12 -0.31 2.55e-9 Ulcerative colitis; LIHC cis rs7131987 0.650 rs7954871 chr12:29459732 G/A cg05697976 chr12:29376483 FAR2 0.28 5.72 0.3 2.32e-8 QT interval; LIHC cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.18e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs655641 1.000 rs622220 chr11:85725621 C/T cg09030501 chr11:85779252 PICALM -0.49 -6.01 -0.31 4.73e-9 Platelet count; LIHC cis rs3540 0.512 rs3930162 chr15:91075129 C/T cg22089800 chr15:90895588 ZNF774 -0.53 -7.48 -0.38 6.23e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs7106204 0.609 rs12804374 chr11:24338016 A/G ch.11.24196551F chr11:24239977 NA 0.66 5.78 0.3 1.71e-8 Response to Homoharringtonine (cytotoxicity); LIHC trans rs2749592 0.588 rs2504144 chr10:38383525 C/T cg17830980 chr10:43048298 ZNF37B -0.43 -7.72 -0.39 1.28e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6582630 0.622 rs11831595 chr12:38511489 C/A cg26384229 chr12:38710491 ALG10B -0.49 -6.83 -0.35 3.86e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs1882538 0.564 rs12707090 chr7:133115163 G/A cg10665199 chr7:133106180 EXOC4 0.53 8.63 0.42 2.42e-16 Intelligence (multi-trait analysis); LIHC cis rs10792665 0.512 rs7926170 chr11:82583957 A/G cg24227371 chr11:82718527 RAB30 -0.28 -6.69 -0.34 9.32e-11 Obesity-related traits; LIHC cis rs2070488 0.965 rs4679053 chr3:38523495 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.95 0.65 3.35e-43 Electrocardiographic conduction measures; LIHC cis rs655641 0.954 rs634719 chr11:85771065 T/C cg09030501 chr11:85779252 PICALM -0.49 -5.96 -0.31 6.21e-9 Platelet count; LIHC cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg16822855 chr3:40428330 ENTPD3 0.31 5.77 0.3 1.8e-8 Renal cell carcinoma; LIHC cis rs2463822 1.000 rs951677 chr11:62107249 G/C cg06239285 chr11:62104954 ASRGL1 0.97 7.08 0.36 8.01e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs3806843 0.966 rs11958868 chr5:140201420 T/C cg19875535 chr5:140030758 IK 0.36 5.76 0.3 1.89e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs10911363 0.592 rs12117885 chr1:183494214 C/T cg09173681 chr1:183549694 NCF2 -0.56 -10.31 -0.49 7.02e-22 Systemic lupus erythematosus; LIHC cis rs6933660 0.720 rs6913515 chr6:151753470 G/C cg10883421 chr6:151773342 RMND1;C6orf211 0.6 10.02 0.48 6.73e-21 Menarche (age at onset); LIHC cis rs10489202 0.632 rs203781 chr1:167880518 A/C cg24449463 chr1:168025552 DCAF6 -0.64 -9.76 -0.47 5.33e-20 Schizophrenia; LIHC cis rs7124681 0.546 rs7941399 chr11:47890421 A/T cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.34e-24 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs2204008 0.869 rs34438288 chr12:38211582 G/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs79149102 0.579 rs8034149 chr15:75311842 G/C cg17294928 chr15:75287854 SCAMP5 -0.49 -6.3 -0.32 9.3e-10 Lung cancer; LIHC cis rs1580019 0.587 rs6968990 chr7:32552159 C/T cg07520158 chr7:32535189 LSM5;AVL9 -0.64 -9.53 -0.46 2.93e-19 Cognitive ability; LIHC cis rs4407350 0.837 rs4823328 chr22:44908999 C/T cg11695653 chr22:44894386 LDOC1L -0.36 -6.06 -0.31 3.69e-9 Intelligence (multi-trait analysis); LIHC cis rs9354352 0.784 rs2062327 chr6:66689923 C/G cg07460842 chr6:66804631 NA -0.62 -9.47 -0.46 4.89e-19 Initial pursuit acceleration in psychotic disorders; LIHC cis rs9303280 0.901 rs7216558 chr17:38070071 C/T cg11212589 chr17:38028394 ZPBP2 -0.33 -6.69 -0.34 9.17e-11 Self-reported allergy; LIHC cis rs116095464 0.558 rs6962 chr5:256509 G/A cg22857025 chr5:266934 NA -1.5 -16.06 -0.66 1.21e-43 Breast cancer; LIHC cis rs1707322 1.000 rs4660334 chr1:46462126 A/C cg06784218 chr1:46089804 CCDC17 0.34 6.15 0.32 2.11e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25937148 chr3:43147320 C3orf39 -0.45 -6.67 -0.34 1.04e-10 Cognitive function; LIHC cis rs853679 0.517 rs9348794 chr6:28117757 T/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs4727027 0.899 rs4727025 chr7:148862863 A/G cg23583168 chr7:148888333 NA -0.74 -10.48 -0.49 1.83e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg18876405 chr7:65276391 NA 0.56 9.44 0.45 5.79e-19 Aortic root size; LIHC cis rs34779708 0.897 rs7900480 chr10:35338699 A/G cg03585969 chr10:35415529 CREM -0.78 -11.37 -0.52 1.25e-25 Inflammatory bowel disease;Crohn's disease; LIHC cis rs936229 0.784 rs12906946 chr15:75153140 A/G cg14664628 chr15:75095509 CSK -0.77 -10.11 -0.48 3.44e-21 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs4788815 0.513 rs7204967 chr16:71804287 A/G cg06353428 chr16:71660113 MARVELD3 1.29 13.45 0.59 2.15e-33 Metabolite levels; LIHC cis rs929354 0.772 rs1182444 chr7:157024510 A/G cg05182265 chr7:156933206 UBE3C 0.32 6.16 0.32 2.02e-9 Body mass index; LIHC cis rs4906332 1.000 rs8012127 chr14:103942762 G/A cg19000871 chr14:103996768 TRMT61A -0.47 -7.98 -0.4 2.26e-14 Coronary artery disease; LIHC cis rs4423214 0.592 rs10898191 chr11:71194601 G/A cg05163923 chr11:71159392 DHCR7 -0.57 -7.12 -0.36 6.38e-12 Vitamin D levels; LIHC cis rs7523273 0.565 rs12733108 chr1:207887210 C/T cg22525895 chr1:207977042 MIR29B2 0.52 7.77 0.39 9.54e-14 Schizophrenia; LIHC cis rs8141529 0.702 rs469992 chr22:29314899 T/C cg02153584 chr22:29168773 CCDC117 -0.52 -8.06 -0.4 1.27e-14 Lymphocyte counts; LIHC cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg22963979 chr7:1858916 MAD1L1 -0.41 -6.5 -0.33 2.91e-10 Bipolar disorder and schizophrenia; LIHC cis rs7336332 0.598 rs76249173 chr13:28010445 A/G cg22138327 chr13:27999177 GTF3A 0.5 5.73 0.3 2.2e-8 Weight; LIHC trans rs1005277 1.000 rs1005277 chr10:38218259 A/C cg17830980 chr10:43048298 ZNF37B 0.4 7.07 0.36 8.8e-12 Extrinsic epigenetic age acceleration; LIHC cis rs4820539 1.000 rs4822361 chr22:23482718 A/G cg14186256 chr22:23484241 RTDR1 -0.93 -19.71 -0.73 2.57e-58 Bone mineral density; LIHC cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg21448741 chr8:58168803 NA 0.34 6.13 0.31 2.42e-9 Developmental language disorder (linguistic errors); LIHC cis rs6446731 0.517 rs2798221 chr4:3270488 T/C cg06533319 chr4:3265114 C4orf44 0.31 5.85 0.3 1.17e-8 Mean platelet volume; LIHC cis rs10861342 0.892 rs9634185 chr12:105624825 C/T cg23923672 chr12:105501055 KIAA1033 0.67 7.66 0.38 1.87e-13 IgG glycosylation; LIHC cis rs9818758 0.607 rs10049462 chr3:49309684 C/T cg00383909 chr3:49044727 WDR6 0.77 6.32 0.32 8.14e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs8180040 0.966 rs11130129 chr3:47489885 G/C cg16586182 chr3:47516702 SCAP 0.6 11.71 0.54 7.09e-27 Colorectal cancer; LIHC cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg13047869 chr3:10149882 C3orf24 0.5 6.08 0.31 3.23e-9 Alzheimer's disease; LIHC cis rs12086130 0.892 rs3176468 chr1:51438881 T/C cg07174182 chr1:51127561 FAF1 -0.75 -8.2 -0.41 4.86e-15 Hip circumference adjusted for BMI;Hip circumference; LIHC trans rs4714291 0.963 rs1304602 chr6:40013471 T/G cg02267698 chr19:7991119 CTXN1 0.39 6.39 0.33 5.47e-10 Strep throat; LIHC cis rs7937682 0.632 rs11823089 chr11:111673539 A/G cg09085632 chr11:111637200 PPP2R1B 0.94 13.93 0.6 2.97e-35 Primary sclerosing cholangitis; LIHC trans rs3780486 0.505 rs10758188 chr9:33123386 C/T cg20290983 chr6:43655470 MRPS18A -0.97 -20.3 -0.74 1.15e-60 IgG glycosylation; LIHC cis rs919433 0.617 rs12619333 chr2:198567638 C/G cg00792783 chr2:198669748 PLCL1 -0.43 -6.28 -0.32 1.01e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11098499 0.863 rs6858592 chr4:120458692 G/A cg09307838 chr4:120376055 NA 0.75 11.45 0.53 6.54e-26 Corneal astigmatism; LIHC cis rs7552404 0.727 rs12093623 chr1:76256232 T/G cg03433033 chr1:76189801 ACADM 0.59 7.56 0.38 3.77e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8180040 0.967 rs807935 chr3:47321669 A/G cg16586182 chr3:47516702 SCAP -0.55 -9.99 -0.48 8.46e-21 Colorectal cancer; LIHC cis rs2637266 1.000 rs35991266 chr10:78378733 A/G cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC cis rs6570726 0.967 rs374728 chr6:145854598 T/A cg23711669 chr6:146136114 FBXO30 0.56 10.03 0.48 6.55e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs6570726 0.875 rs373313 chr6:145857791 T/C cg23711669 chr6:146136114 FBXO30 0.56 10.03 0.48 6.55e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.587 rs1466741 chr3:47247214 C/T cg27129171 chr3:47204927 SETD2 -0.56 -9.26 -0.45 2.3e-18 Colorectal cancer; LIHC cis rs561341 0.843 rs4795666 chr17:30241409 A/G cg12193833 chr17:30244370 NA -0.51 -5.94 -0.31 6.92e-9 Hip circumference adjusted for BMI; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26705765 chr19:10252866 DNMT1 0.47 6.11 0.31 2.67e-9 Hepatitis; LIHC cis rs74544699 1.000 rs76595330 chr4:74801272 T/G cg16072462 chr4:74847758 PF4 0.6 6.12 0.31 2.62e-9 Growth-regulated protein alpha levels; LIHC trans rs4566357 0.595 rs6707159 chr2:227909339 T/A cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.62e-9 Coronary artery disease; LIHC cis rs6456156 0.586 rs12203510 chr6:167473006 C/T cg07741184 chr6:167504864 NA 0.28 6.62 0.34 1.38e-10 Primary biliary cholangitis; LIHC cis rs3008870 0.958 rs34367328 chr1:67445321 T/C cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg02931644 chr1:25747376 RHCE -0.33 -7.06 -0.36 9.29e-12 Erythrocyte sedimentation rate; LIHC cis rs1577917 1.000 rs10944169 chr6:86683036 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.54 -9.65 -0.46 1.19e-19 Response to antipsychotic treatment; LIHC cis rs7131987 0.903 rs10843373 chr12:29420608 A/T cg14222432 chr12:29376421 FAR2 0.36 6.87 0.35 3.12e-11 QT interval; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13319278 chr19:633649 POLRMT 0.43 6.12 0.31 2.61e-9 Lung function (FEV1/FVC); LIHC cis rs11792861 0.855 rs116127510 chr9:111868344 G/A cg05043794 chr9:111880884 C9orf5 -0.31 -7.24 -0.36 3.07e-12 Menarche (age at onset); LIHC cis rs67981189 0.593 rs9806042 chr14:71530993 G/C cg15816911 chr14:71606274 NA 0.43 6.93 0.35 2.12e-11 Schizophrenia; LIHC cis rs11792861 0.816 rs11791845 chr9:111683898 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.9 0.43 3.24e-17 Menarche (age at onset); LIHC cis rs11098499 0.863 rs10034450 chr4:120455649 A/G cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg18876405 chr7:65276391 NA 0.56 9.46 0.46 5.21e-19 Calcium levels; LIHC cis rs5769765 0.862 rs9616384 chr22:50313082 C/T cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg00149659 chr3:10157352 C3orf10 0.69 7.07 0.36 8.52e-12 Alzheimer's disease; LIHC cis rs7772486 0.754 rs697054 chr6:146003770 C/T cg23711669 chr6:146136114 FBXO30 0.74 12.96 0.57 1.59e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs317689 0.658 rs479971 chr12:69672471 A/G cg20891283 chr12:69753455 YEATS4 0.52 7.53 0.38 4.55e-13 Response to diuretic therapy; LIHC cis rs12497850 0.931 rs11705888 chr3:48817289 T/C cg07636037 chr3:49044803 WDR6 0.93 17.07 0.68 1.12e-47 Parkinson's disease; LIHC cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg03721293 chr16:90014378 DEF8 0.42 6.9 0.35 2.47e-11 Skin colour saturation; LIHC cis rs9611565 0.592 rs80477 chr22:42001183 C/T cg03806693 chr22:41940476 POLR3H 0.85 9.43 0.45 6.49e-19 Vitiligo; LIHC cis rs6546550 0.933 rs6546555 chr2:70135760 A/G cg02498382 chr2:70120550 SNRNP27 -0.44 -7.61 -0.38 2.69e-13 Prevalent atrial fibrillation; LIHC cis rs6450176 0.638 rs1542167 chr5:53305742 T/G ch.5.1024479R chr5:53302184 ARL15 -1.01 -18.11 -0.7 6.85e-52 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs8180040 0.903 rs11710013 chr3:47296921 T/C cg02527881 chr3:46936655 PTH1R -0.32 -6.14 -0.32 2.3e-9 Colorectal cancer; LIHC cis rs11690935 0.843 rs9784123 chr2:172785005 T/A cg13550731 chr2:172543902 DYNC1I2 -0.81 -14.37 -0.61 5.58e-37 Schizophrenia; LIHC trans rs2727020 0.724 rs4109837 chr11:49372051 A/T cg18944383 chr4:111397179 ENPEP 0.28 6.52 0.33 2.56e-10 Coronary artery disease; LIHC cis rs367615 0.959 rs17161951 chr5:108930590 A/G cg17395555 chr5:108820864 NA -0.32 -6.61 -0.34 1.48e-10 Colorectal cancer (SNP x SNP interaction); LIHC cis rs2380220 0.751 rs117986000 chr6:95923454 A/C cg15832292 chr6:96025679 MANEA -0.62 -6.79 -0.34 5.11e-11 Behavioural disinhibition (generation interaction); LIHC cis rs7582720 1.000 rs78907692 chr2:203932176 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs473651 0.904 rs472247 chr2:239362573 G/A cg18131467 chr2:239335373 ASB1 1.05 19.18 0.72 3.44e-56 Multiple system atrophy; LIHC cis rs2066819 1.000 rs2066808 chr12:56737973 A/G cg26734620 chr12:56694298 CS 1.0 10.11 0.48 3.46e-21 Psoriasis vulgaris; LIHC cis rs9916302 0.861 rs2338801 chr17:37490780 G/T cg03013999 chr17:37608204 MED1 -0.36 -6.04 -0.31 4e-9 Glomerular filtration rate (creatinine); LIHC trans rs6596140 0.620 rs10515463 chr5:133032214 C/T cg19518232 chr4:120222109 C4orf3 -0.46 -6.45 -0.33 3.87e-10 Hypertension; LIHC cis rs9457247 1.000 rs436707 chr6:167388843 T/C cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs2075371 1.000 rs2544221 chr7:133993014 G/C cg11752832 chr7:134001865 SLC35B4 0.52 7.68 0.38 1.67e-13 Mean platelet volume; LIHC cis rs16944613 0.541 rs4288973 chr15:91093676 G/A cg26821196 chr15:91095069 CRTC3 0.46 7.98 0.4 2.23e-14 Colorectal cancer; LIHC trans rs1728785 0.901 rs1728797 chr16:68570989 A/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.15 0.32 2.13e-9 Ulcerative colitis; LIHC cis rs1030877 1.000 rs2576743 chr2:105901337 C/T cg02079111 chr2:105885981 TGFBRAP1 0.66 11.68 0.53 9.79e-27 Obesity-related traits; LIHC cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg11764359 chr7:65958608 NA 0.56 5.99 0.31 5.28e-9 Diabetic kidney disease; LIHC cis rs2370759 1.000 rs78959390 chr10:32616346 C/T cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18909525 chr9:132403873 ASB6 0.41 6.26 0.32 1.18e-9 Cognitive function; LIHC cis rs826838 1.000 rs11183469 chr12:38752311 G/A cg26384229 chr12:38710491 ALG10B 1.04 13.79 0.6 1.09e-34 Heart rate; LIHC cis rs2607426 0.681 rs8109099 chr19:41282509 T/A cg20631044 chr19:41255890 C19orf54;SNRPA 0.54 6.26 0.32 1.15e-9 Blood protein levels; LIHC cis rs6938 0.534 rs12913293 chr15:75184458 G/C cg14664628 chr15:75095509 CSK -0.47 -6.58 -0.34 1.75e-10 Breast cancer; LIHC cis rs2635047 0.967 rs2576060 chr18:44637106 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.49 -6.73 -0.34 7.26e-11 Educational attainment; LIHC cis rs67311347 1.000 rs2305521 chr3:40429183 A/G cg24209194 chr3:40518798 ZNF619 0.4 5.73 0.3 2.2e-8 Renal cell carcinoma; LIHC cis rs16858210 0.607 rs57874587 chr3:183584749 C/T cg25686905 chr3:183603175 PARL -0.48 -8.56 -0.42 3.82e-16 Menopause (age at onset); LIHC cis rs1434579 0.652 rs7249536 chr19:44938980 G/A cg15540054 chr19:45004280 ZNF180 0.65 9.83 0.47 3.04e-20 Tuberculosis; LIHC cis rs10751667 0.857 rs7481221 chr11:966813 G/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg09455208 chr3:40491958 NA -0.41 -8.44 -0.42 9e-16 Renal cell carcinoma; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26390924 chr15:50613702 GABPB1 0.38 6.08 0.31 3.18e-9 Hepatitis; LIHC cis rs9616064 0.531 rs17821649 chr22:47050387 G/A cg05621596 chr22:47072043 GRAMD4 -0.7 -10.8 -0.5 1.39e-23 Urate levels in obese individuals; LIHC cis rs6714710 0.603 rs11691494 chr2:98419726 T/A cg26665480 chr2:98280029 ACTR1B 0.43 6.11 0.31 2.71e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs908922 0.676 rs2181172 chr1:152491794 A/G cg23254163 chr1:152506842 NA 0.22 5.8 0.3 1.48e-8 Hair morphology; LIHC cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg22105103 chr4:187893119 NA 0.34 8.82 0.43 6.1e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs655641 1.000 rs592314 chr11:85673124 A/G cg09030501 chr11:85779252 PICALM -0.5 -6.05 -0.31 3.75e-9 Platelet count; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs13191362 0.938 rs35395472 chr6:163008493 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs3820068 0.581 rs1122386 chr1:15946877 C/T cg17385448 chr1:15911702 AGMAT 0.35 6.11 0.31 2.64e-9 Systolic blood pressure; LIHC cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg24549020 chr5:56110836 MAP3K1 0.52 6.73 0.34 6.97e-11 Initial pursuit acceleration; LIHC cis rs12477438 0.520 rs6542865 chr2:99764521 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.23 0.61 1.96e-36 Chronic sinus infection; LIHC cis rs4650994 0.571 rs6700047 chr1:178508742 G/A cg05350800 chr1:178550844 NA -0.3 -6.47 -0.33 3.41e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7216064 1.000 rs62084238 chr17:65856573 T/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.21 -0.45 3.25e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs3018712 0.532 rs4930587 chr11:68415135 T/C cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.12e-8 Total body bone mineral density; LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.06e-19 Renal cell carcinoma; LIHC cis rs10791323 0.517 rs1120245 chr11:133745290 A/G cg06766960 chr11:133703094 NA -0.41 -6.14 -0.32 2.31e-9 Childhood ear infection; LIHC cis rs9871864 0.734 rs4405944 chr3:20367764 C/A cg00235661 chr3:20228976 SGOL1 0.3 5.76 0.3 1.85e-8 Behavioural disinhibition (generation interaction); LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg21724239 chr8:58056113 NA 0.57 7.5 0.38 5.53e-13 Developmental language disorder (linguistic errors); LIHC cis rs651907 0.535 rs34263427 chr3:101507805 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.16 0.48 2.36e-21 Colorectal cancer; LIHC cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg23205692 chr1:25664452 TMEM50A -0.37 -6.01 -0.31 4.67e-9 Erythrocyte sedimentation rate; LIHC cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg17971929 chr21:40555470 PSMG1 0.52 7.97 0.4 2.43e-14 Cognitive function; LIHC cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg08392591 chr16:89556376 ANKRD11 0.53 8.23 0.41 3.86e-15 Multiple myeloma (IgH translocation); LIHC cis rs9430161 0.611 rs12081181 chr1:11034165 T/G cg02454025 chr1:11042201 C1orf127 0.96 18.16 0.7 4.49e-52 Ewing sarcoma; LIHC trans rs875971 0.545 rs4718335 chr7:65804606 C/T cg26939375 chr7:64535504 NA 0.4 6.34 0.32 7.06e-10 Aortic root size; LIHC cis rs2439831 1.000 rs1814538 chr15:43759774 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.79 -13.56 -0.59 7.88e-34 Lung cancer in ever smokers; LIHC cis rs1018836 0.847 rs4735225 chr8:91569100 G/C cg16814680 chr8:91681699 NA -0.62 -9.77 -0.47 4.92e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7589728 1.000 rs75309929 chr2:88524377 T/C cg04511125 chr2:88470314 THNSL2 0.74 6.91 0.35 2.41e-11 Plasma clusterin levels; LIHC cis rs763121 0.815 rs9306328 chr22:39028913 C/T cg21395723 chr22:39101663 GTPBP1 0.35 5.98 0.31 5.67e-9 Menopause (age at onset); LIHC cis rs4319547 0.774 rs7307233 chr12:123124301 C/G cg05707623 chr12:122985044 ZCCHC8 -0.5 -6.86 -0.35 3.24e-11 Body mass index; LIHC cis rs2050392 0.590 rs2065723 chr10:30720462 A/T cg18806716 chr10:30721971 MAP3K8 -0.4 -5.76 -0.3 1.87e-8 Inflammatory bowel disease; LIHC cis rs57590327 0.716 rs3772891 chr3:81776760 A/G cg07356753 chr3:81810745 GBE1 0.52 7.69 0.38 1.58e-13 Extraversion; LIHC cis rs6665290 0.835 rs7549465 chr1:227214399 A/C cg10327440 chr1:227177885 CDC42BPA -1.12 -21.39 -0.76 4.76e-65 Myeloid white cell count; LIHC cis rs782590 0.522 rs12329050 chr2:55894428 G/A cg18811423 chr2:55921094 PNPT1 -0.56 -8.38 -0.41 1.39e-15 Metabolic syndrome; LIHC cis rs5769765 0.542 rs738707 chr22:50250827 G/A cg02269571 chr22:50332266 NA 0.69 7.94 0.39 2.89e-14 Schizophrenia; LIHC cis rs1008375 1.000 rs6818639 chr4:17633049 A/G cg16339924 chr4:17578868 LAP3 0.45 6.3 0.32 9.35e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12493885 0.818 rs61791541 chr3:153758155 G/T cg10247383 chr3:153839028 SGEF 0.64 5.95 0.31 6.7e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2153535 0.580 rs1577467 chr6:8444241 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs1395 0.744 rs62130714 chr2:27532870 A/G cg21248554 chr2:27665150 KRTCAP3 -0.48 -5.77 -0.3 1.76e-8 Blood metabolite levels; LIHC cis rs1046896 1.000 rs1046875 chr17:80685426 A/G cg02711726 chr17:80685570 FN3KRP 0.59 11.99 0.54 7.09e-28 Glycated hemoglobin levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02127607 chr17:61920694 SMARCD2 -0.4 -6.12 -0.31 2.62e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6430585 0.591 rs77096272 chr2:136663605 C/A cg07305463 chr2:136567211 LCT -0.39 -6.04 -0.31 3.94e-9 Corneal structure; LIHC cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.15e-10 Diabetic kidney disease; LIHC cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.81 -0.35 4.48e-11 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC trans rs7937682 1.000 rs7937682 chr11:111579939 C/G cg18187862 chr3:45730750 SACM1L 0.54 6.11 0.31 2.79e-9 Primary sclerosing cholangitis; LIHC cis rs2439831 0.867 rs28415933 chr15:43635800 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.31 0.52 2.11e-25 Lung cancer in ever smokers; LIHC cis rs4979906 1.000 rs12264636 chr10:79448539 C/G cg07817648 chr10:79422355 NA 0.29 6.19 0.32 1.73e-9 Mortality in heart failure; LIHC cis rs17384381 1.000 rs17388521 chr1:85897904 A/G cg16011679 chr1:85725395 C1orf52 -0.81 -8.63 -0.42 2.29e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs796364 0.806 rs79053279 chr2:201057443 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -6.94 -0.35 1.98e-11 Schizophrenia; LIHC cis rs611744 0.550 rs1448154 chr8:109281053 T/C cg18478394 chr8:109455254 TTC35 0.44 7.61 0.38 2.77e-13 Dupuytren's disease; LIHC cis rs7927592 0.913 rs12284933 chr11:68319489 G/A cg20283391 chr11:68216788 NA -0.52 -7.85 -0.39 5.44e-14 Total body bone mineral density; LIHC cis rs16870629 0.567 rs35661060 chr5:1060379 G/A cg18655438 chr5:1077845 SLC12A7 0.36 5.83 0.3 1.26e-8 QT interval; LIHC cis rs9814567 1.000 rs11708531 chr3:134224902 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.29 -0.55 5.27e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs921968 0.541 rs72965126 chr2:219330189 C/T cg02176678 chr2:219576539 TTLL4 -0.57 -7.96 -0.4 2.58e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs2204008 0.805 rs3863360 chr12:37966432 C/T cg26384229 chr12:38710491 ALG10B 0.81 10.49 0.49 1.62e-22 Bladder cancer; LIHC cis rs743757 0.878 rs9867588 chr3:50526880 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.42 6.27 0.32 1.08e-9 Diastolic blood pressure; LIHC cis rs631288 0.793 rs10900331 chr1:146733128 C/G cg25205988 chr1:146714368 CHD1L 0.78 8.24 0.41 3.82e-15 PR interval in Tripanosoma cruzi seropositivity; LIHC cis rs36051895 0.623 rs6476952 chr9:5236924 T/C cg02405213 chr9:5042618 JAK2 -0.6 -9.7 -0.46 8.48e-20 Pediatric autoimmune diseases; LIHC cis rs6750047 0.771 rs1056837 chr2:38298150 A/G cg07380506 chr2:38303506 CYP1B1 0.59 7.63 0.38 2.43e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg07424592 chr7:64974309 NA -0.8 -9.08 -0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs775227 0.574 rs34286076 chr3:113269695 G/C cg18753928 chr3:113234510 CCDC52 -0.46 -5.92 -0.3 7.85e-9 Dental caries; LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg17178900 chr1:205818956 PM20D1 0.66 9.86 0.47 2.45e-20 Menarche (age at onset); LIHC cis rs16854884 0.632 rs59287916 chr3:143638337 G/A cg06585982 chr3:143692056 C3orf58 0.61 8.48 0.42 7.1e-16 Economic and political preferences (feminism/equality); LIHC cis rs4668356 0.773 rs11883894 chr2:172034974 G/C cg13882835 chr2:172017928 TLK1 0.43 5.88 0.3 9.85e-9 Cognitive performance; LIHC trans rs61931739 0.500 rs11053166 chr12:34385898 A/C cg26384229 chr12:38710491 ALG10B -0.75 -8.91 -0.43 3.07e-17 Morning vs. evening chronotype; LIHC cis rs1144333 0.655 rs946164 chr1:76383286 A/T cg10523679 chr1:76189770 ACADM 0.46 6.14 0.31 2.34e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs67311347 1.000 rs9874006 chr3:40471596 G/A cg18306943 chr3:40428807 ENTPD3 0.34 6.06 0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs7223966 0.881 rs3020608 chr17:61979993 C/A cg05941027 chr17:61774174 LIMD2 0.31 6.0 0.31 5.14e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs875971 0.895 rs6460300 chr7:65952924 A/G cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs3862030 0.694 rs1984795 chr10:104226830 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.42 -0.37 9.58e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs7914558 0.966 rs2065977 chr10:104729415 C/T cg15744005 chr10:104629667 AS3MT -0.41 -9.34 -0.45 1.23e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs79040073 0.911 rs17393193 chr15:49332079 T/C cg04482760 chr15:49339272 SECISBP2L -0.47 -5.8 -0.3 1.49e-8 Lung cancer in ever smokers; LIHC cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg03060546 chr3:49711283 APEH 0.38 5.72 0.3 2.38e-8 Menarche (age at onset); LIHC cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.58 8.22 0.41 4.13e-15 Lymphocyte counts; LIHC cis rs6782228 0.675 rs9813845 chr3:128399623 G/C cg16766828 chr3:128327626 NA -0.43 -6.61 -0.34 1.44e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC trans rs8073060 0.586 rs9303690 chr17:34005513 C/T cg19694781 chr19:47549865 TMEM160 -1.25 -13.3 -0.58 8.06e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9611565 0.512 rs139572 chr22:42214532 C/T cg03806693 chr22:41940476 POLR3H -0.76 -7.77 -0.39 9.23e-14 Vitiligo; LIHC cis rs11608355 0.545 rs55902232 chr12:109902305 G/A cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs611744 0.870 rs633794 chr8:109174702 A/G cg21045802 chr8:109455806 TTC35 0.58 9.97 0.47 1.01e-20 Dupuytren's disease; LIHC cis rs1775715 0.870 rs3847415 chr10:32219456 G/T cg14930904 chr10:32216787 ARHGAP12 0.38 6.76 0.34 5.84e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs7772486 0.790 rs6926076 chr6:146232804 C/T cg13319975 chr6:146136371 FBXO30 0.35 5.81 0.3 1.44e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg05484376 chr2:27715224 FNDC4 0.37 6.29 0.32 9.92e-10 Total body bone mineral density; LIHC cis rs7959452 0.868 rs12812860 chr12:69746671 T/C cg22834771 chr12:69754056 YEATS4 -0.37 -5.96 -0.31 6.19e-9 Blood protein levels; LIHC cis rs6598955 0.543 rs12125620 chr1:26552238 G/A cg04990556 chr1:26633338 UBXN11 0.75 10.59 0.5 7.73e-23 Obesity-related traits; LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg02782426 chr3:40428986 ENTPD3 0.33 6.07 0.31 3.34e-9 Renal cell carcinoma; LIHC cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg11645453 chr3:52864694 ITIH4 0.22 6.04 0.31 4.06e-9 Bipolar disorder; LIHC cis rs1707322 1.000 rs12124847 chr1:46380850 T/A cg06784218 chr1:46089804 CCDC17 0.36 6.31 0.32 8.71e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs116095464 0.558 rs6872854 chr5:209038 G/T cg22496380 chr5:211416 CCDC127 -1.02 -10.11 -0.48 3.29e-21 Breast cancer; LIHC cis rs6570726 0.967 rs9403706 chr6:145795187 C/T cg23711669 chr6:146136114 FBXO30 -0.47 -8.19 -0.4 5.34e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs365132 1.000 rs353490 chr5:176433063 C/T cg16309518 chr5:176445507 NA -0.58 -11.56 -0.53 2.58e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs10508774 1.000 rs117817425 chr10:32879194 C/A cg01819863 chr10:32635814 EPC1 0.65 6.01 0.31 4.73e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1018836 0.608 rs11997663 chr8:91474484 A/C cg16814680 chr8:91681699 NA -0.36 -5.78 -0.3 1.7e-8 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9486719 0.894 rs34826652 chr6:96899085 A/G cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.32e-12 Migraine;Coronary artery disease; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg11070056 chr1:107600091 PRMT6 -0.72 -12.38 -0.56 2.53e-29 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12986413 1.000 rs4807208 chr19:2170205 A/C cg09261902 chr19:2140048 AP3D1 0.37 6.27 0.32 1.1e-9 Height; LIHC cis rs523522 0.962 rs4767904 chr12:120930798 T/G cg27279351 chr12:120934652 DYNLL1 0.66 12.03 0.55 4.94e-28 High light scatter reticulocyte count; LIHC cis rs1008375 1.000 rs2109522 chr4:17658645 T/A cg15017067 chr4:17643749 FAM184B 0.34 5.83 0.3 1.29e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4919087 0.705 rs701812 chr10:98975413 A/G cg25902810 chr10:99078978 FRAT1 -0.54 -6.25 -0.32 1.22e-9 Monocyte count; LIHC cis rs1198430 0.925 rs7534474 chr1:23773851 A/G cg19827787 chr1:23763612 ASAP3 0.36 6.38 0.33 5.7e-10 Total cholesterol levels; LIHC cis rs7131987 0.845 rs2042511 chr12:29408780 C/T cg16970926 chr12:29381810 FAR2 0.29 6.1 0.31 2.81e-9 QT interval; LIHC cis rs13217239 0.646 rs11756275 chr6:27007113 A/C cg12292205 chr6:26970375 C6orf41 -0.45 -7.73 -0.39 1.19e-13 Schizophrenia; LIHC cis rs798554 0.548 rs1639064 chr7:2896544 G/A cg13628971 chr7:2884303 GNA12 0.43 7.5 0.38 5.59e-13 Height; LIHC cis rs7589728 0.620 rs76687350 chr2:88473832 G/A cg14558114 chr2:88469736 THNSL2 0.64 6.21 0.32 1.56e-9 Plasma clusterin levels; LIHC cis rs8084351 0.577 rs4534924 chr18:50642112 G/A cg24270629 chr18:50823537 DCC 0.43 6.36 0.33 6.37e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs4908760 0.795 rs6693009 chr1:8743710 A/G cg20416874 chr1:8611966 RERE -0.61 -11.53 -0.53 3.29e-26 Vitiligo; LIHC cis rs9399135 1.000 rs6569988 chr6:135352303 C/A cg22676075 chr6:135203613 NA 0.38 6.34 0.32 7.1e-10 Red blood cell count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10494282 chr1:44440945 ATP6V0B 0.47 6.82 0.35 4.02e-11 Lung function (FEV1/FVC); LIHC cis rs11030122 0.702 rs10835340 chr11:3960420 A/G cg18678763 chr11:4115507 RRM1 0.56 8.22 0.41 4.29e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs9309473 1.000 rs56672945 chr2:73622663 C/T cg20560298 chr2:73613845 ALMS1 -0.59 -6.87 -0.35 3.07e-11 Metabolite levels; LIHC cis rs757081 0.636 rs214934 chr11:17193475 T/A cg15432903 chr11:17409602 KCNJ11 -0.42 -5.81 -0.3 1.44e-8 Systolic blood pressure; LIHC cis rs2806561 0.894 rs598438 chr1:23531563 C/T cg19743168 chr1:23544995 NA 0.43 8.06 0.4 1.31e-14 Height; LIHC trans rs1994135 0.654 rs11052759 chr12:33724126 G/A cg26384229 chr12:38710491 ALG10B 0.48 6.45 0.33 3.84e-10 Resting heart rate; LIHC cis rs2576037 0.583 rs10070 chr18:44388899 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.87 -0.3 1.02e-8 Personality dimensions; LIHC cis rs17001868 1.000 rs73167022 chr22:40797256 A/T cg07138101 chr22:40742427 ADSL 0.58 6.31 0.32 8.78e-10 Mammographic density (dense area); LIHC cis rs2153535 0.580 rs1577472 chr6:8486215 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs7953249 0.791 rs1920792 chr12:121404584 T/C cg02403541 chr12:121454288 C12orf43 -0.34 -5.93 -0.31 7.27e-9 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC trans rs2262909 0.962 rs11673195 chr19:22313814 T/C cg17074339 chr11:11642133 GALNTL4 0.47 7.34 0.37 1.54e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg27211696 chr2:191398769 TMEM194B 0.66 10.91 0.51 5.38e-24 Pulse pressure; LIHC cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg12310025 chr6:25882481 NA -1.03 -12.74 -0.57 1.11e-30 Intelligence (multi-trait analysis); LIHC cis rs425277 0.628 rs10797427 chr1:2060732 C/T cg04315214 chr1:2043799 PRKCZ 0.39 6.23 0.32 1.4e-9 Height; LIHC cis rs1801251 1.000 rs1867778 chr2:233679644 C/T cg25237894 chr2:233734115 C2orf82 -0.58 -11.44 -0.53 6.85e-26 Coronary artery disease; LIHC cis rs6500602 0.610 rs1659499 chr16:4595269 G/A cg08645402 chr16:4508243 NA -0.38 -6.88 -0.35 2.9100000000000002e-11 Schizophrenia; LIHC cis rs4423214 1.000 rs11546509 chr11:71162785 A/G cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs17253792 0.822 rs74653073 chr14:56079528 T/C cg01858014 chr14:56050164 KTN1 -0.69 -6.6 -0.34 1.56e-10 Putamen volume; LIHC cis rs1348850 0.645 rs13431091 chr2:178434615 A/G cg27490568 chr2:178487706 NA 0.83 10.02 0.48 7.1e-21 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg03806693 chr22:41940476 POLR3H -0.99 -10.44 -0.49 2.57e-22 Vitiligo; LIHC trans rs7726839 0.540 rs3792720 chr5:643028 T/G cg25482853 chr8:67687455 SGK3 0.6 6.05 0.31 3.75e-9 Obesity-related traits; LIHC cis rs986417 0.901 rs1956558 chr14:60975956 T/C cg27398547 chr14:60952738 C14orf39 0.77 8.43 0.41 1.01e-15 Gut microbiota (bacterial taxa); LIHC cis rs6424115 0.679 rs2076345 chr1:24083494 C/T cg15997130 chr1:24165203 NA -0.36 -6.4 -0.33 5.1e-10 Immature fraction of reticulocytes; LIHC cis rs3770081 1.000 rs17026854 chr2:86280496 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.45 6.24 0.32 1.28e-9 Facial emotion recognition (sad faces); LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg00106254 chr7:1943704 MAD1L1 -0.46 -7.67 -0.38 1.81e-13 Bipolar disorder and schizophrenia; LIHC trans rs1005277 0.522 rs7072977 chr10:37940440 C/A cg17830980 chr10:43048298 ZNF37B -0.42 -8.09 -0.4 1.03e-14 Extrinsic epigenetic age acceleration; LIHC cis rs970821 0.966 rs4549748 chr8:124743332 G/A cg00283535 chr8:124749564 ANXA13 0.36 6.09 0.31 3e-9 Breast cancer; LIHC cis rs7264396 0.561 rs6058388 chr20:34571846 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -8.4 -0.41 1.21e-15 Total cholesterol levels; LIHC cis rs6120849 0.754 rs6087666 chr20:33640242 G/A cg24642439 chr20:33292090 TP53INP2 0.65 7.05 0.36 9.65e-12 Protein C levels; LIHC cis rs208520 0.954 rs12190073 chr6:66983740 T/C cg07460842 chr6:66804631 NA 0.67 7.3 0.37 2e-12 Exhaled nitric oxide output; LIHC trans rs561341 1.000 rs7216102 chr17:30259450 A/G cg20587970 chr11:113659929 NA -0.56 -6.61 -0.34 1.45e-10 Hip circumference adjusted for BMI; LIHC cis rs7647973 1.000 rs62259933 chr3:49469703 G/A cg07636037 chr3:49044803 WDR6 -0.54 -6.68 -0.34 9.5e-11 Menarche (age at onset); LIHC cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg23758822 chr17:41437982 NA 0.94 17.54 0.69 1.39e-49 Menopause (age at onset); LIHC cis rs2832191 0.967 rs1999321 chr21:30530233 A/C cg24692254 chr21:30365293 RNF160 0.54 9.33 0.45 1.38e-18 Dental caries; LIHC cis rs2257205 0.667 rs9889631 chr17:56630359 G/T cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs116095464 0.558 rs6878061 chr5:223072 A/G cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs9303280 0.776 rs9910826 chr17:38035648 A/G cg11212589 chr17:38028394 ZPBP2 0.35 7.09 0.36 7.92e-12 Self-reported allergy; LIHC cis rs1799949 0.894 rs71367985 chr17:41374463 G/A cg23758822 chr17:41437982 NA 0.9 16.59 0.67 9.5e-46 Menopause (age at onset); LIHC cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg05368731 chr17:41323189 NBR1 0.73 12.63 0.56 2.82e-30 Menopause (age at onset); LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg09417038 chr21:47716443 C21orf57 0.52 7.94 0.39 2.93e-14 Testicular germ cell tumor; LIHC trans rs1814175 0.645 rs28445479 chr11:50047999 A/G cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs4474465 0.688 rs4367973 chr11:78284545 C/A cg02023728 chr11:77925099 USP35 -0.34 -5.97 -0.31 6.07e-9 Alzheimer's disease (survival time); LIHC cis rs9486715 0.838 rs9320127 chr6:96865358 G/A cg06623918 chr6:96969491 KIAA0776 0.85 14.77 0.62 1.57e-38 Headache; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg07479988 chr2:39103277 MORN2;DHX57 -0.41 -6.15 -0.32 2.15e-9 Triglycerides; LIHC cis rs1355223 0.583 rs2941041 chr11:34874734 A/C cg11058730 chr11:34937778 PDHX;APIP 0.76 13.96 0.6 2.22e-35 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13783546 chr17:76671452 CYTH1 0.42 6.3 0.32 9.41e-10 Longevity; LIHC cis rs3091242 0.934 rs686631 chr1:25719599 A/T cg23205692 chr1:25664452 TMEM50A 0.4 6.43 0.33 4.25e-10 Erythrocyte sedimentation rate; LIHC cis rs6665290 0.566 rs1513617 chr1:227447213 C/T cg10327440 chr1:227177885 CDC42BPA 0.88 13.43 0.59 2.55e-33 Myeloid white cell count; LIHC cis rs11958404 0.932 rs6870115 chr5:157436960 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs561341 0.709 rs8068049 chr17:30183857 T/C cg20587970 chr11:113659929 NA 0.63 6.17 0.32 1.91e-9 Hip circumference adjusted for BMI; LIHC cis rs7408868 0.908 rs4809028 chr19:15273231 A/G cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC cis rs7927592 0.731 rs488381 chr11:68291693 G/A cg01657329 chr11:68192670 LRP5 0.49 7.27 0.37 2.5e-12 Total body bone mineral density; LIHC trans rs11098499 0.562 rs13101722 chr4:120555975 C/A cg25214090 chr10:38739885 LOC399744 -0.43 -7.08 -0.36 8.34e-12 Corneal astigmatism; LIHC cis rs7103648 0.695 rs6485758 chr11:47530024 G/A cg20307385 chr11:47447363 PSMC3 1.01 16.7 0.67 3.3e-46 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs17376456 0.877 rs10059230 chr5:93450347 A/G cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 0.43 6.13 0.31 2.38e-9 Colorectal cancer; LIHC cis rs950169 0.580 rs11634320 chr15:85172183 A/C cg03959625 chr15:84868606 LOC388152 -0.43 -6.11 -0.31 2.69e-9 Schizophrenia; LIHC cis rs9549260 0.564 rs9646110 chr13:41308301 A/T cg21288729 chr13:41239152 FOXO1 -0.46 -6.98 -0.35 1.51e-11 Red blood cell count; LIHC cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg00750074 chr16:89608354 SPG7 -0.5 -7.9 -0.39 3.74e-14 Multiple myeloma (IgH translocation); LIHC cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC cis rs4919694 1.000 rs17727044 chr10:104821256 A/T cg04362960 chr10:104952993 NT5C2 1.08 7.54 0.38 4.15e-13 Arsenic metabolism; LIHC cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.61e-12 Bipolar disorder; LIHC cis rs743757 1.000 rs2282752 chr3:50433967 G/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.54 8.54 0.42 4.53e-16 Diastolic blood pressure; LIHC cis rs1568889 0.887 rs7102237 chr11:28344296 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 14.47 0.62 2.26e-37 Bipolar disorder; LIHC cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg05564831 chr3:52568323 NT5DC2 0.38 6.18 0.32 1.83e-9 Bipolar disorder; LIHC cis rs9467773 0.587 rs9467722 chr6:26352566 T/C cg09904177 chr6:26538194 HMGN4 -0.37 -5.94 -0.31 7.09e-9 Intelligence (multi-trait analysis); LIHC cis rs2645694 0.626 rs2703122 chr4:77821418 A/C cg06046430 chr4:77819534 ANKRD56 0.5 6.53 0.33 2.34e-10 Emphysema distribution in smoking; LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg00960700 chr17:80709150 TBCD -0.37 -6.13 -0.31 2.42e-9 Glycated hemoglobin levels; LIHC cis rs6674970 1.000 rs6674970 chr1:151116279 C/T cg03258749 chr1:151040405 MLLT11 -0.46 -7.19 -0.36 4.15e-12 Childhood ear infection; LIHC cis rs7572733 0.515 rs893808 chr2:198860837 C/G cg00792783 chr2:198669748 PLCL1 0.45 6.56 0.33 2.04e-10 Dermatomyositis; LIHC cis rs2191566 0.881 rs1996408 chr19:44532732 G/A cg20607764 chr19:44506953 ZNF230 -0.44 -7.18 -0.36 4.51e-12 Acute lymphoblastic leukemia (childhood); LIHC trans rs11039798 0.512 rs3974936 chr11:49005012 C/T cg15704280 chr7:45808275 SEPT13 0.57 6.37 0.33 6.02e-10 Axial length; LIHC cis rs11098499 0.754 rs28643450 chr4:120245242 G/A cg09307838 chr4:120376055 NA 0.71 11.25 0.52 3.46e-25 Corneal astigmatism; LIHC cis rs11229555 1.000 rs3168135 chr11:58386177 G/A cg15696309 chr11:58395628 NA -0.73 -8.95 -0.44 2.24e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7071206 0.853 rs66786803 chr10:79429941 A/G cg07817648 chr10:79422355 NA -0.28 -5.89 -0.3 9.15e-9 Bone mineral density; LIHC cis rs611744 0.967 rs598477 chr8:109187874 G/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs12644436 0.526 rs9998083 chr4:88771391 A/C cg06891869 chr4:88767617 MEPE -0.49 -7.75 -0.39 1.05e-13 HIV-1 viral setpoint; LIHC cis rs6445975 0.575 rs7614726 chr3:58243289 C/T cg23715586 chr3:58305044 RPP14 -0.34 -5.74 -0.3 2.13e-8 Systemic lupus erythematosus; LIHC cis rs1144333 0.655 rs12401729 chr1:76336586 T/G cg22875332 chr1:76189707 ACADM 0.44 6.44 0.33 4.14e-10 Attention function in attention deficit hyperactive disorder; LIHC trans rs2243480 1.000 rs313802 chr7:65516373 A/G cg10756647 chr7:56101905 PSPH 1.08 13.33 0.58 6.29e-33 Diabetic kidney disease; LIHC cis rs2032447 0.530 rs9356996 chr6:26008487 C/A cg03264133 chr6:25882463 NA -0.52 -6.72 -0.34 7.69e-11 Intelligence (multi-trait analysis); LIHC cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.05 -0.31 3.7e-9 Aortic root size; LIHC cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg26119090 chr2:26468346 HADHA;HADHB -1.14 -17.46 -0.69 2.95e-49 Gut microbiome composition (summer); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg26820233 chr16:838206 RPUSD1;CHTF18 -0.45 -6.24 -0.32 1.32e-9 Migraine with aura; LIHC cis rs700651 0.789 rs10190226 chr2:198901564 A/G cg00792783 chr2:198669748 PLCL1 -0.43 -6.21 -0.32 1.55e-9 Intracranial aneurysm; LIHC cis rs11760633 0.672 rs11763500 chr7:1826385 T/A cg23422044 chr7:1970798 MAD1L1 -0.37 -5.71 -0.3 2.41e-8 Coronary artery disease; LIHC cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg27170947 chr2:26402098 FAM59B -0.69 -8.54 -0.42 4.54e-16 Gut microbiome composition (summer); LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs589448 0.902 rs2603090 chr12:69777188 G/A cg14784868 chr12:69753453 YEATS4 0.97 22.6 0.77 7.56e-70 Cerebrospinal fluid biomarker levels; LIHC cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg00166722 chr3:10149974 C3orf24 0.53 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC trans rs877282 0.891 rs11599917 chr10:762288 G/A cg22713356 chr15:30763199 NA 1.37 12.03 0.55 4.86e-28 Uric acid levels; LIHC cis rs4803468 1.000 rs10422783 chr19:41906436 T/C cg09537434 chr19:41945824 ATP5SL -1.0 -21.06 -0.75 1.02e-63 Height; LIHC cis rs3736594 0.527 rs62141279 chr2:27771415 C/T cg27432699 chr2:27873401 GPN1 0.46 6.7 0.34 8.52e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs12497850 0.765 rs12487580 chr3:49182932 G/A cg06212747 chr3:49208901 KLHDC8B 0.6 7.93 0.39 3.18e-14 Parkinson's disease; LIHC cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg07308232 chr7:1071921 C7orf50 -0.51 -8.17 -0.4 6.21e-15 Longevity;Endometriosis; LIHC cis rs9457247 0.534 rs1130033 chr6:167385623 C/T cg23791538 chr6:167370224 RNASET2 -0.79 -14.57 -0.62 9.28e-38 Crohn's disease; LIHC cis rs1005277 0.579 rs2505240 chr10:38442419 G/T cg25427524 chr10:38739819 LOC399744 -0.64 -12.27 -0.55 6.52e-29 Extrinsic epigenetic age acceleration; LIHC cis rs7193541 0.662 rs8052367 chr16:74658867 G/A cg01733217 chr16:74700730 RFWD3 0.93 22.33 0.77 9.16e-69 Multiple myeloma; LIHC cis rs6089584 0.888 rs6587283 chr20:60613727 A/C cg06108461 chr20:60628389 TAF4 -1.01 -17.29 -0.68 1.4e-48 Body mass index; LIHC cis rs986417 0.818 rs8005621 chr14:61106699 G/A cg27398547 chr14:60952738 C14orf39 0.66 7.38 0.37 1.19e-12 Gut microbiota (bacterial taxa); LIHC cis rs875971 0.545 rs73150604 chr7:65945532 T/A cg11764359 chr7:65958608 NA 0.59 8.21 0.41 4.58e-15 Aortic root size; LIHC cis rs2839186 0.843 rs17182671 chr21:47696238 T/C cg09417038 chr21:47716443 C21orf57 -0.5 -7.29 -0.37 2.12e-12 Testicular germ cell tumor; LIHC cis rs4474465 1.000 rs10899517 chr11:78180507 A/T cg02023728 chr11:77925099 USP35 0.33 5.89 0.3 9.28e-9 Alzheimer's disease (survival time); LIHC cis rs2842992 0.724 rs9365097 chr6:160211259 G/A cg11366901 chr6:160182831 ACAT2 0.87 14.69 0.62 3.31e-38 Age-related macular degeneration (geographic atrophy); LIHC cis rs1005277 0.589 rs2749624 chr10:38529865 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.41 -6.12 -0.31 2.58e-9 Extrinsic epigenetic age acceleration; LIHC cis rs769267 0.965 rs13964 chr19:19468710 C/G cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.12 -0.31 2.6e-9 Tonsillectomy; LIHC cis rs2832191 0.791 rs7282843 chr21:30475226 A/G cg24692254 chr21:30365293 RNF160 0.68 12.49 0.56 9.47e-30 Dental caries; LIHC cis rs751728 0.965 rs2296743 chr6:33740025 C/T cg25922239 chr6:33757077 LEMD2 0.43 7.22 0.36 3.46e-12 Crohn's disease; LIHC cis rs7223966 1.000 rs56057198 chr17:61733332 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 6.83 0.35 3.81e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs10504229 0.679 rs7840100 chr8:58036662 T/G cg20607798 chr8:58055168 NA 0.46 6.62 0.34 1.42e-10 Developmental language disorder (linguistic errors); LIHC cis rs9814567 1.000 rs13090969 chr3:134307257 C/A cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.22 0.32 1.49e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2997447 0.739 rs60141220 chr1:26395741 G/A cg19633962 chr1:26362018 EXTL1 -0.5 -5.82 -0.3 1.38e-8 QRS complex (12-leadsum); LIHC cis rs568617 0.953 rs1151519 chr11:65645831 G/C cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.44 -0.33 4.17e-10 Crohn's disease; LIHC cis rs1712517 1.000 rs1163084 chr10:105039048 T/C cg05636881 chr10:105038444 INA 0.41 6.59 0.34 1.62e-10 Migraine; LIHC cis rs8067354 0.527 rs1292039 chr17:57974913 A/T cg13753209 chr17:57696993 CLTC 0.71 10.6 0.5 6.68e-23 Hemoglobin concentration; LIHC cis rs2882877 0.661 rs35623329 chr2:190443445 T/C cg10752008 chr2:190445175 SLC40A1 0.54 6.25 0.32 1.19e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs79057730 0.639 rs6463933 chr7:793954 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.81 8.95 0.44 2.25e-17 Initial pursuit acceleration; LIHC cis rs7833790 0.724 rs4739627 chr8:82734657 A/G cg27398817 chr8:82754497 SNX16 -0.32 -5.85 -0.3 1.14e-8 Diastolic blood pressure; LIHC cis rs11711311 1.000 rs12736 chr3:113530211 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.47 8.84 0.43 5.08e-17 IgG glycosylation; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg16132339 chr22:24313637 DDTL;DDT 0.8 15.72 0.65 2.69e-42 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs798554 0.616 rs1636251 chr7:2884720 T/C cg04166393 chr7:2884313 GNA12 0.37 6.08 0.31 3.23e-9 Height; LIHC cis rs62458065 0.640 rs4141788 chr7:32519264 T/C cg06627557 chr7:32535165 LSM5;AVL9 -0.72 -7.18 -0.36 4.42e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs11583043 0.918 rs3850453 chr1:101408933 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 6.2 0.32 1.67e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg02187348 chr16:89574699 SPG7 0.51 7.65 0.38 2.07e-13 Multiple myeloma (IgH translocation); LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg02034447 chr16:89574710 SPG7 0.49 7.52 0.38 4.88e-13 Multiple myeloma (IgH translocation); LIHC cis rs11758351 0.588 rs2050948 chr6:26234952 A/G cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg21448741 chr8:58168803 NA 0.34 6.37 0.33 5.94e-10 Developmental language disorder (linguistic errors); LIHC cis rs6121246 0.529 rs6060210 chr20:30187681 C/T cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs921968 0.541 rs7583449 chr2:219403022 A/C cg02985541 chr2:219472218 PLCD4 -0.42 -6.84 -0.35 3.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs3761847 0.622 rs10818498 chr9:123787566 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 6.05 0.31 3.77e-9 Rheumatoid arthritis; LIHC cis rs4853036 0.951 rs61422548 chr2:70110249 G/T cg02498382 chr2:70120550 SNRNP27 -0.39 -6.31 -0.32 8.61e-10 Colorectal or endometrial cancer; LIHC cis rs67981189 0.593 rs221919 chr14:71588229 A/G cg15816911 chr14:71606274 NA -0.44 -7.03 -0.36 1.16e-11 Schizophrenia; LIHC cis rs10792665 0.631 rs10736758 chr11:82635214 C/T cg24227371 chr11:82718527 RAB30 -0.27 -6.07 -0.31 3.33e-9 Obesity-related traits; LIHC cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.05e-17 Bipolar disorder; LIHC cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg05555928 chr11:63887634 MACROD1 0.55 7.47 0.37 6.77e-13 Mean platelet volume; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.7 0.38 1.51e-13 Height; LIHC cis rs10791097 0.694 rs10160281 chr11:130742788 T/C cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15228606 chr17:1812096 NA 0.41 6.03 0.31 4.17e-9 Pancreatic cancer; LIHC cis rs11190604 1.000 rs12355721 chr10:102244911 C/T cg07080220 chr10:102295463 HIF1AN 0.5 7.08 0.36 8.02e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17760058 chr19:2321626 LSM7 0.41 6.18 0.32 1.85e-9 Immature fraction of reticulocytes; LIHC cis rs67311347 1.000 rs12638199 chr3:40475285 A/G cg18306943 chr3:40428807 ENTPD3 0.33 5.84 0.3 1.21e-8 Renal cell carcinoma; LIHC cis rs9517320 0.534 rs9556962 chr13:99156648 C/T cg20487152 chr13:99095054 FARP1 -0.4 -6.73 -0.34 7.33e-11 Longevity; LIHC cis rs7726558 0.543 rs76930980 chr5:118839793 G/A cg05185946 chr5:118791606 HSD17B4 -0.3 -6.0 -0.31 5.05e-9 QT interval (sulfonylurea treatment interaction); LIHC cis rs7618501 1.000 rs11130221 chr3:49819102 C/G cg21467203 chr3:49911342 NA -0.4 -6.93 -0.35 2.16e-11 Intelligence (multi-trait analysis); LIHC cis rs412000 0.507 rs2680688 chr17:56450524 T/C cg25039879 chr17:56429692 SUPT4H1 -0.52 -6.47 -0.33 3.37e-10 Primary tooth development (time to first tooth eruption); LIHC cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg00106254 chr7:1943704 MAD1L1 -0.41 -6.52 -0.33 2.57e-10 Bipolar disorder and schizophrenia; LIHC cis rs1559088 1.000 rs28840147 chr19:33561976 A/G cg27124370 chr19:33622961 WDR88 0.47 7.04 0.36 1.09e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6089584 0.528 rs881994 chr20:60623931 G/A cg06108461 chr20:60628389 TAF4 -0.63 -8.72 -0.43 1.2e-16 Body mass index; LIHC cis rs9733 0.818 rs6694531 chr1:150683512 C/A cg13175981 chr1:150552382 MCL1 0.52 8.07 0.4 1.17e-14 Tonsillectomy; LIHC cis rs412000 0.554 rs2680700 chr17:56440542 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.44 5.98 0.31 5.59e-9 Primary tooth development (time to first tooth eruption); LIHC cis rs9549328 0.921 rs9549623 chr13:113640293 G/A cg08890338 chr13:113700818 MCF2L -0.35 -5.81 -0.3 1.41e-8 Systolic blood pressure; LIHC cis rs919433 0.889 rs787995 chr2:198216853 T/G cg03934865 chr2:198174659 NA 0.55 8.81 0.43 6.28e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9902453 0.904 rs9894893 chr17:28270350 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.99 0.6 1.73e-35 Coffee consumption (cups per day); LIHC trans rs11039798 0.591 rs74992349 chr11:49019252 G/A cg15704280 chr7:45808275 SEPT13 0.6 6.7 0.34 8.82e-11 Axial length; LIHC cis rs875971 0.862 rs6460307 chr7:66060871 A/G cg11764359 chr7:65958608 NA 0.72 12.46 0.56 1.26e-29 Aortic root size; LIHC cis rs9921222 0.521 rs757460 chr16:367174 G/C cg00101154 chr16:420108 MRPL28 -0.57 -7.69 -0.38 1.62e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs11098499 0.863 rs11098532 chr4:120490726 C/A cg09307838 chr4:120376055 NA 0.75 11.85 0.54 2.2e-27 Corneal astigmatism; LIHC cis rs3753275 0.690 rs6577500 chr1:8614571 G/C cg20416874 chr1:8611966 RERE -0.49 -6.21 -0.32 1.54e-9 Educational attainment; LIHC cis rs4268898 0.735 rs34125395 chr2:24558242 C/T cg06627628 chr2:24431161 ITSN2 0.45 6.48 0.33 3.11e-10 Asthma; LIHC cis rs7044106 0.762 rs7024046 chr9:123419178 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 8.1 0.4 9.91e-15 Hip circumference adjusted for BMI; LIHC cis rs11711311 1.000 rs9288984 chr3:113525956 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.99 -0.35 1.48e-11 IgG glycosylation; LIHC cis rs8016982 0.559 rs10133562 chr14:81732758 C/T cg01989461 chr14:81687754 GTF2A1 -0.47 -7.87 -0.39 4.69e-14 Schizophrenia; LIHC cis rs6582630 0.538 rs7971292 chr12:38498151 A/G cg26384229 chr12:38710491 ALG10B -0.48 -6.69 -0.34 8.87e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg02290350 chr8:58132656 NA 0.4 8.26 0.41 3.23e-15 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.643 rs832801 chr2:219488698 G/A cg02985541 chr2:219472218 PLCD4 0.43 7.99 0.4 2.14e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.86 0.8 1.15e-78 Prudent dietary pattern; LIHC cis rs921968 0.643 rs590771 chr2:219369851 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.71 0.43 1.33e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs6748734 1.000 rs4675874 chr2:241819796 A/G cg09990169 chr2:241835740 C2orf54 0.65 9.17 0.44 4.48e-18 Urinary metabolites; LIHC cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.55e-21 Intelligence (multi-trait analysis); LIHC cis rs5769765 0.908 rs9616217 chr22:50318946 C/T cg26441486 chr22:50317300 CRELD2 0.39 6.67 0.34 1.01e-10 Schizophrenia; LIHC cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.95 8.45 0.42 8.22e-16 Platelet count; LIHC cis rs13191362 1.000 rs35449999 chr6:163023465 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.65 5.77 0.3 1.8e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs311392 0.902 rs2666874 chr8:55091561 A/T cg11783602 chr8:55087084 NA 0.31 6.06 0.31 3.68e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs904251 0.797 rs1776460 chr6:37485484 A/G cg01843034 chr6:37503916 NA -0.5 -7.99 -0.4 2.02e-14 Cognitive performance; LIHC cis rs12079745 0.623 rs115415855 chr1:169322993 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -6.96 -0.35 1.77e-11 QT interval; LIHC trans rs1814175 0.817 rs10769618 chr11:49822336 A/G cg18944383 chr4:111397179 ENPEP 0.27 7.04 0.36 1.09e-11 Height; LIHC cis rs7582180 0.764 rs7425797 chr2:100928337 T/C cg14675211 chr2:100938903 LONRF2 0.53 8.28 0.41 2.83e-15 Intelligence (multi-trait analysis); LIHC cis rs4474465 0.850 rs10793330 chr11:78269985 T/C cg27205649 chr11:78285834 NARS2 0.39 5.93 0.31 7.41e-9 Alzheimer's disease (survival time); LIHC cis rs35306767 0.953 rs11253521 chr10:976416 G/C cg26597838 chr10:835615 NA 0.96 11.96 0.54 8.6e-28 Eosinophil percentage of granulocytes; LIHC cis rs2760061 0.819 rs964941 chr1:228193857 G/A cg02753203 chr1:228287806 NA 0.48 7.92 0.39 3.25e-14 Diastolic blood pressure; LIHC cis rs1801251 0.963 rs6739638 chr2:233576015 G/A cg08000102 chr2:233561755 GIGYF2 0.75 11.28 0.52 2.61e-25 Coronary artery disease; LIHC cis rs919433 0.713 rs2045245 chr2:198485341 A/C cg10820045 chr2:198174542 NA 0.52 8.21 0.41 4.61e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2404602 0.735 rs2461870 chr15:76813920 T/G cg03037974 chr15:76606532 NA -0.59 -10.21 -0.48 1.54e-21 Blood metabolite levels; LIHC cis rs7193541 0.508 rs7188581 chr16:74672901 T/A cg01733217 chr16:74700730 RFWD3 0.92 21.87 0.76 5.98e-67 Multiple myeloma; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.93 0.57 2.07e-31 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg12463550 chr7:65579703 CRCP 0.69 7.19 0.36 4.02e-12 Diabetic kidney disease; LIHC cis rs7520050 0.931 rs6697557 chr1:46307809 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7086627 0.515 rs7077373 chr10:82211615 C/T cg01528321 chr10:82214614 TSPAN14 0.54 7.64 0.38 2.2e-13 Post bronchodilator FEV1; LIHC cis rs875971 0.545 rs73376401 chr7:65639828 G/A cg11764359 chr7:65958608 NA 0.51 6.98 0.35 1.56e-11 Aortic root size; LIHC cis rs8180040 0.966 rs1872164 chr3:47415100 G/A cg27129171 chr3:47204927 SETD2 -0.58 -9.86 -0.47 2.38e-20 Colorectal cancer; LIHC cis rs763014 0.932 rs2269560 chr16:682442 A/C cg00908189 chr16:619842 PIGQ 0.81 12.74 0.57 1.12e-30 Height; LIHC cis rs785830 0.717 rs542669 chr9:224367 G/C cg14500300 chr9:211689 NA 0.3 6.9 0.35 2.61e-11 Platelet distribution width; LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg19635926 chr16:89946313 TCF25 0.52 6.87 0.35 3.06e-11 Skin colour saturation; LIHC cis rs12586317 0.620 rs79832710 chr14:35547434 G/T cg16230307 chr14:35515116 FAM177A1 0.8 13.41 0.59 3.01e-33 Psoriasis; LIHC cis rs1008375 0.932 rs6814465 chr4:17659034 C/T cg02297831 chr4:17616191 MED28 0.43 6.12 0.31 2.6e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4919694 1.000 rs78214351 chr10:104822688 A/G cg04362960 chr10:104952993 NT5C2 1.14 8.85 0.43 4.77e-17 Arsenic metabolism; LIHC cis rs2019216 0.542 rs8073228 chr17:21909838 C/G cg22648282 chr17:21454238 C17orf51 -0.43 -7.1 -0.36 7.37e-12 Pelvic organ prolapse; LIHC cis rs7116495 0.609 rs4477459 chr11:71720616 T/C cg10381502 chr11:71823885 C11orf51 -1.06 -9.3 -0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs2933343 1.000 rs1680790 chr3:128625853 G/T cg25356066 chr3:128598488 ACAD9 0.53 7.0 0.35 1.39e-11 IgG glycosylation; LIHC cis rs2380220 0.808 rs2716074 chr6:95907662 T/C cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs2153535 0.580 rs1414349 chr6:8472290 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs6582630 0.598 rs10880645 chr12:38556172 G/A cg26384229 chr12:38710491 ALG10B -0.5 -7.01 -0.35 1.24e-11 Drug-induced liver injury (flucloxacillin); LIHC trans rs6578985 0.769 rs4929957 chr11:2128309 C/T cg20230732 chr3:128721448 CCDC48 0.37 6.18 0.32 1.85e-9 Femoral neck bone geometry and menarche (age at onset); LIHC cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04400940 chr3:150329548 SELT 0.42 6.05 0.31 3.75e-9 Pancreatic cancer; LIHC cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg07636037 chr3:49044803 WDR6 0.77 12.97 0.57 1.42e-31 Menarche (age at onset); LIHC cis rs12477438 0.871 rs13396584 chr2:99611768 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.67 7.93 0.39 3.14e-14 Chronic sinus infection; LIHC cis rs801193 0.935 rs2286683 chr7:66129843 G/A cg18876405 chr7:65276391 NA -0.43 -7.37 -0.37 1.31e-12 Aortic root size; LIHC cis rs12594515 0.548 rs55932467 chr15:45997124 C/T cg01629716 chr15:45996671 NA 0.53 5.84 0.3 1.24e-8 Waist circumference;Weight; LIHC trans rs2727020 0.675 rs1684258 chr11:49340020 G/A cg15704280 chr7:45808275 SEPT13 0.75 10.66 0.5 4.25e-23 Coronary artery disease; LIHC cis rs7551222 0.721 rs4252717 chr1:204512100 T/C cg20240347 chr1:204465584 NA -0.36 -7.56 -0.38 3.85e-13 Schizophrenia; LIHC cis rs1801251 1.000 rs6437074 chr2:233712296 C/T cg25237894 chr2:233734115 C2orf82 -0.59 -11.55 -0.53 2.92e-26 Coronary artery disease; LIHC cis rs4819052 0.851 rs10470246 chr21:46659017 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.04e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09015484 chr9:96929106 NA 0.4 6.65 0.34 1.15e-10 Cognitive function; LIHC cis rs9951602 0.703 rs2959407 chr18:76682915 A/G cg00806245 chr18:76673096 NA -0.23 -6.12 -0.31 2.6e-9 Obesity-related traits; LIHC cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg05368731 chr17:41323189 NBR1 0.73 12.58 0.56 4.43e-30 Menopause (age at onset); LIHC cis rs644799 0.635 rs10831428 chr11:95508404 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 12.15 0.55 1.8e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg14671364 chr1:107599128 PRMT6 -0.52 -7.59 -0.38 3.1e-13 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7116495 1.000 rs2845857 chr11:71715215 C/G cg26138937 chr11:71823887 C11orf51 -0.77 -7.74 -0.39 1.14e-13 Severe influenza A (H1N1) infection; LIHC cis rs67478160 0.643 rs7147171 chr14:104264857 G/A cg08213375 chr14:104286397 PPP1R13B 0.65 12.86 0.57 3.97e-31 Schizophrenia; LIHC cis rs138249 0.902 rs138240 chr22:50564181 A/C cg24864161 chr22:50528282 MOV10L1 -0.36 -5.93 -0.31 7.37e-9 Gestational age at birth in labor-initiated deliveries (child effect); LIHC cis rs801193 0.569 rs2659892 chr7:66200305 A/G cg11764359 chr7:65958608 NA 0.75 12.68 0.57 1.77e-30 Aortic root size; LIHC cis rs12971120 0.947 rs8084109 chr18:72168312 T/A cg25817165 chr18:72167213 CNDP2 -0.68 -12.68 -0.57 1.9e-30 Refractive error; LIHC cis rs1385374 0.858 rs10773578 chr12:129290026 G/C cg09035930 chr12:129282057 SLC15A4 -0.5 -5.96 -0.31 6.13e-9 Systemic lupus erythematosus; LIHC cis rs716804 0.740 rs10743131 chr11:10266856 C/T cg01453529 chr11:10209919 SBF2 -0.29 -5.86 -0.3 1.12e-8 Neuroticism; LIHC cis rs7582180 0.629 rs6731549 chr2:100939937 T/G cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs853679 0.517 rs6932109 chr6:28078303 A/G cg23485639 chr6:28045615 ZNF165 -0.45 -5.97 -0.31 6.01e-9 Depression; LIHC cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.61 0.34 1.46e-10 Bipolar disorder; LIHC cis rs8027181 0.839 rs7176223 chr15:73077742 T/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.5 7.58 0.38 3.33e-13 Triglyceride levels; LIHC cis rs9341808 1.000 rs9341808 chr6:80953257 C/A cg08355045 chr6:80787529 NA 0.3 5.95 0.31 6.49e-9 Sitting height ratio; LIHC cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg12463550 chr7:65579703 CRCP 0.68 7.32 0.37 1.82e-12 Diabetic kidney disease; LIHC cis rs12477438 1.000 rs17760953 chr2:99859863 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.8 -9.2 -0.45 3.57e-18 Chronic sinus infection; LIHC cis rs2236918 0.710 rs2526702 chr1:242017983 G/A cg17736920 chr1:242011382 EXO1 0.44 6.55 0.33 2.06e-10 Menopause (age at onset); LIHC cis rs9549367 0.789 rs3861720 chr13:113906097 A/G cg18105134 chr13:113819100 PROZ -0.68 -11.64 -0.53 1.29e-26 Platelet distribution width; LIHC cis rs6545883 0.894 rs7602859 chr2:61458206 A/T cg14146966 chr2:61757674 XPO1 -0.43 -7.12 -0.36 6.22e-12 Tuberculosis; LIHC cis rs7927771 0.832 rs11605672 chr11:47413733 A/G cg20135002 chr11:47629003 NA -0.52 -8.8 -0.43 6.76e-17 Subjective well-being; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15910486 chr5:142783621 NR3C1 -0.55 -6.18 -0.32 1.8e-9 Systolic blood pressure; LIHC cis rs35306767 0.903 rs34270014 chr10:904666 T/C cg20503657 chr10:835505 NA 1.07 12.08 0.55 3.31e-28 Eosinophil percentage of granulocytes; LIHC cis rs1552244 0.882 rs2130813 chr3:10038706 A/C cg08888203 chr3:10149979 C3orf24 0.47 6.0 0.31 5.15e-9 Alzheimer's disease; LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg00656387 chr3:40428638 ENTPD3 -0.51 -8.72 -0.43 1.24e-16 Renal cell carcinoma; LIHC cis rs2115536 1.000 rs7163338 chr15:80198408 C/G cg11839771 chr15:80205821 ST20 -0.32 -6.72 -0.34 7.5e-11 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs6723226 0.842 rs2754522 chr2:32801257 C/G cg02381751 chr2:32503542 YIPF4 0.77 11.61 0.53 1.65e-26 Intelligence (multi-trait analysis); LIHC cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg09323728 chr8:95962352 TP53INP1 -0.35 -7.83 -0.39 6.39e-14 Type 2 diabetes; LIHC cis rs694739 0.726 rs17857342 chr11:64138905 T/G cg02228329 chr11:64053129 BAD;GPR137 0.59 8.13 0.4 8.09e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs1814175 0.558 rs5025146 chr11:49795724 C/G cg18944383 chr4:111397179 ENPEP 0.27 6.96 0.35 1.78e-11 Height; LIHC cis rs9682041 0.800 rs7643085 chr3:170070371 A/G cg11886554 chr3:170076028 SKIL 0.79 6.54 0.33 2.25e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC trans rs11662586 0.517 rs7230837 chr18:77695384 A/T cg05926928 chr17:57297772 GDPD1 0.41 6.21 0.32 1.51e-9 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs9326778 0.520 rs62375284 chr5:108842127 A/T cg17395555 chr5:108820864 NA -0.37 -6.35 -0.32 6.96e-10 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs17376456 1.000 rs67150649 chr5:93292377 A/G cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs1878931 0.580 rs4785932 chr16:3410456 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.85 14.96 0.63 2.83e-39 Body mass index (adult); LIHC cis rs80282103 0.867 rs17155821 chr10:1071701 A/G cg18964960 chr10:1102726 WDR37 0.67 6.37 0.33 5.99e-10 Glomerular filtration rate (creatinine); LIHC cis rs921968 0.643 rs832802 chr2:219386899 C/T cg17980119 chr2:219472607 PLCD4 0.35 6.05 0.31 3.84e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs15676 0.947 rs3115874 chr9:131579338 G/C cg00228799 chr9:131580591 ENDOG 0.46 7.01 0.35 1.26e-11 Blood metabolite levels; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg14828511 chr1:107599125 PRMT6 -0.43 -6.06 -0.31 3.68e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1577917 0.771 rs10944133 chr6:86358984 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -8.1 -0.4 9.63e-15 Response to antipsychotic treatment; LIHC cis rs10927875 0.864 rs12135073 chr1:16167799 C/T cg21385522 chr1:16154831 NA 1.06 13.61 0.59 5.41e-34 Dilated cardiomyopathy; LIHC cis rs4654899 1.000 rs6669102 chr1:21355543 A/G cg08539965 chr1:21396338 EIF4G3 0.34 5.93 0.31 7.29e-9 Superior frontal gyrus grey matter volume; LIHC cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg18404041 chr3:52824283 ITIH1 -0.48 -7.61 -0.38 2.65e-13 Electroencephalogram traits; LIHC cis rs2153535 0.580 rs7341206 chr6:8470489 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs4988958 0.565 rs1420100 chr2:103037002 C/A cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma (childhood onset); LIHC cis rs2257205 0.667 rs9899893 chr17:56754597 T/C cg12560992 chr17:57184187 TRIM37 0.71 7.79 0.39 8.05e-14 Pancreatic cancer; LIHC cis rs769267 0.930 rs9917108 chr19:19572785 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.0 0.4 1.99e-14 Tonsillectomy; LIHC cis rs2370759 1.000 rs7910776 chr10:32639093 C/T cg18270830 chr10:32634957 EPC1 0.52 6.29 0.32 9.59e-10 Sexual dysfunction (female); LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 9.27e-15 Prudent dietary pattern; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg26338869 chr17:61819248 STRADA 0.6 8.81 0.43 6.54e-17 Prudent dietary pattern; LIHC cis rs4908768 0.871 rs7553298 chr1:8770883 A/G cg20416874 chr1:8611966 RERE 0.54 8.59 0.42 3.11e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27138727 chr3:107150777 NA 0.42 6.3 0.32 9.35e-10 Cognitive function; LIHC cis rs155076 1.000 rs261423 chr13:21852331 A/C cg11317459 chr13:21872234 NA -1.15 -13.36 -0.59 4.64e-33 White matter hyperintensity burden; LIHC cis rs4466137 0.553 rs16898 chr5:82986149 T/C cg16102102 chr5:83017553 HAPLN1 -0.43 -7.23 -0.36 3.18e-12 Prostate cancer; LIHC cis rs28595532 0.748 rs17594978 chr4:119336398 T/C cg21605333 chr4:119757512 SEC24D 1.08 8.7 0.43 1.4e-16 Cannabis dependence symptom count; LIHC cis rs9322817 0.691 rs2499658 chr6:105291412 A/G cg02098413 chr6:105308735 HACE1 0.45 8.39 0.41 1.31e-15 Thyroid stimulating hormone; LIHC cis rs36051895 0.632 rs7850484 chr9:5147817 C/T cg02405213 chr9:5042618 JAK2 -0.62 -9.66 -0.46 1.12e-19 Pediatric autoimmune diseases; LIHC cis rs9534288 0.797 rs4942467 chr13:46599817 A/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg25072359 chr17:41440525 NA 0.39 6.31 0.32 8.87e-10 Menopause (age at onset); LIHC cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg20607798 chr8:58055168 NA 0.6 8.96 0.44 2.14e-17 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.85 0.39 5.53e-14 Prudent dietary pattern; LIHC cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg02187348 chr16:89574699 SPG7 0.63 9.84 0.47 2.89e-20 Multiple myeloma (IgH translocation); LIHC cis rs1371867 0.846 rs1788204 chr8:101303936 C/T cg06636551 chr8:101224915 SPAG1 -0.5 -9.06 -0.44 1.02e-17 Atrioventricular conduction; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg21976603 chr20:61516759 DIDO1 0.46 6.64 0.34 1.25e-10 Longevity; LIHC cis rs8067354 0.645 rs2645487 chr17:57886125 T/G cg02344993 chr17:57696989 CLTC 0.72 12.37 0.56 2.76e-29 Hemoglobin concentration; LIHC cis rs7523273 0.526 rs2724375 chr1:207997973 C/A cg22525895 chr1:207977042 MIR29B2 -0.62 -9.74 -0.47 5.83e-20 Schizophrenia; LIHC cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg02034447 chr16:89574710 SPG7 -0.42 -6.38 -0.33 5.63e-10 Multiple myeloma (IgH translocation); LIHC cis rs7786877 0.761 rs11772705 chr7:100298904 T/C cg20848291 chr7:100343083 ZAN -0.46 -6.95 -0.35 1.88e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1062177 0.901 rs1549622 chr5:151266049 A/G cg00977110 chr5:151150581 G3BP1 0.49 6.27 0.32 1.11e-9 Preschool internalizing problems; LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg11766577 chr21:47581405 C21orf56 -0.45 -7.41 -0.37 9.98e-13 Testicular germ cell tumor; LIHC cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.01 0.54 5.93e-28 Alzheimer's disease; LIHC cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.36 0.41 1.6e-15 Platelet count; LIHC cis rs710216 0.536 rs710221 chr1:43414200 G/A cg07803811 chr1:43423981 SLC2A1 0.43 6.59 0.34 1.65e-10 Red cell distribution width; LIHC cis rs929354 0.772 rs6459739 chr7:156998863 A/T cg16102536 chr7:156981717 UBE3C 0.35 5.85 0.3 1.17e-8 Body mass index; LIHC cis rs743757 1.000 rs6446206 chr3:50455470 G/A cg12708802 chr3:50388878 TUSC4;CYB561D2 0.47 7.33 0.37 1.63e-12 Diastolic blood pressure; LIHC cis rs1577917 1.000 rs12665321 chr6:86769289 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.31 -0.37 1.84e-12 Response to antipsychotic treatment; LIHC cis rs2073300 0.609 rs3736755 chr20:23377642 C/T cg12062639 chr20:23401060 NAPB 1.07 14.38 0.61 5.24e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs1843834 0.539 rs10177898 chr2:225437552 C/T cg22455342 chr2:225449267 CUL3 0.61 8.81 0.43 6.51e-17 IgE levels in asthmatics (D.p. specific); LIHC cis rs10733682 0.659 rs3906146 chr9:129463613 C/T cg00232160 chr9:129468157 NA 0.35 6.1 0.31 2.92e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg00091569 chr3:40428383 ENTPD3 0.4 6.73 0.34 7.1e-11 Renal cell carcinoma; LIHC cis rs9828933 0.882 rs3816156 chr3:63999712 A/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.72 -9.05 -0.44 1.09e-17 Type 2 diabetes; LIHC cis rs17401966 0.931 rs11584023 chr1:10302596 A/G cg19773385 chr1:10388646 KIF1B -0.39 -7.0 -0.35 1.34e-11 Hepatocellular carcinoma; LIHC cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg07061783 chr6:25882402 NA -0.43 -6.07 -0.31 3.41e-9 Blood metabolite levels; LIHC cis rs7546668 1.000 rs4661640 chr1:15854882 T/G cg11706911 chr1:15910989 AGMAT 0.44 6.82 0.35 4.05e-11 Glomerular filtration rate (creatinine); LIHC cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.58 8.75 0.43 9.98e-17 Schizophrenia; LIHC cis rs6960043 0.818 rs12699673 chr7:15049604 T/C cg19272540 chr7:15055459 NA 0.27 7.27 0.37 2.43e-12 Type 2 diabetes; LIHC cis rs1577917 1.000 rs1577919 chr6:86757296 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.04 -0.48 5.98e-21 Response to antipsychotic treatment; LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.89 0.78 5.76e-71 Height; LIHC cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg09222892 chr1:25734099 RHCE -0.45 -8.14 -0.4 7.61e-15 Erythrocyte sedimentation rate; LIHC cis rs1385374 0.563 rs12299194 chr12:129264838 A/G cg21616243 chr12:129299702 MGC16384;SLC15A4 0.55 6.87 0.35 2.98e-11 Systemic lupus erythematosus; LIHC cis rs9549367 0.713 rs9549357 chr13:113860121 C/T cg18105134 chr13:113819100 PROZ -0.66 -12.02 -0.54 5.36e-28 Platelet distribution width; LIHC cis rs7264396 0.563 rs2425079 chr20:34298191 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC cis rs67311347 1.000 rs11129876 chr3:40401636 C/T cg24209194 chr3:40518798 ZNF619 -0.43 -6.32 -0.32 8.15e-10 Renal cell carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17450446 chr1:160002111 PIGM 0.5 6.47 0.33 3.37e-10 Lung function (FEV1/FVC); LIHC cis rs7095944 0.585 rs11245357 chr10:126452042 A/G cg08799069 chr10:126477246 METTL10 -0.38 -6.75 -0.34 6.32e-11 Asthma; LIHC trans rs911555 0.755 rs2756122 chr14:103983033 C/G cg17675199 chr6:35436792 RPL10A 0.38 7.71 0.38 1.39e-13 Intelligence (multi-trait analysis); LIHC cis rs3106136 0.967 rs3106135 chr4:95138308 G/A cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.18 -0.4 5.45e-15 Capecitabine sensitivity; LIHC cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1580019 0.587 rs6951955 chr7:32548761 A/T cg06627557 chr7:32535165 LSM5;AVL9 1.13 25.87 0.81 1.63e-82 Cognitive ability; LIHC cis rs7647973 0.560 rs77473999 chr3:49777660 T/C cg03060546 chr3:49711283 APEH -0.56 -6.09 -0.31 3.09e-9 Menarche (age at onset); LIHC cis rs8060686 0.641 rs28508024 chr16:68126606 T/C cg05110241 chr16:68378359 PRMT7 -0.57 -6.61 -0.34 1.48e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs2290416 0.710 rs61005957 chr8:144669512 T/G cg26536354 chr8:144654954 C8orf73 0.54 6.17 0.32 1.94e-9 Attention deficit hyperactivity disorder; LIHC cis rs1580019 0.961 rs1580021 chr7:32497702 T/G cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg09904177 chr6:26538194 HMGN4 0.57 11.56 0.53 2.61e-26 Intelligence (multi-trait analysis); LIHC cis rs9325144 0.625 rs11534879 chr12:38968165 A/G cg26384229 chr12:38710491 ALG10B -0.44 -6.2 -0.32 1.67e-9 Morning vs. evening chronotype; LIHC cis rs1008375 0.966 rs6825133 chr4:17577776 C/T cg02297831 chr4:17616191 MED28 0.48 7.28 0.37 2.31e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs45567533 0.790 rs7427574 chr3:38684835 C/G cg14758556 chr20:62440591 NA 0.4 6.28 0.32 1.01e-9 PR interval; LIHC cis rs13161895 1.000 rs27012 chr5:179402211 A/C cg02702477 chr5:179499311 RNF130 0.71 9.94 0.47 1.28e-20 LDL cholesterol; LIHC cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg21448741 chr8:58168803 NA 0.35 6.51 0.33 2.69e-10 Developmental language disorder (linguistic errors); LIHC cis rs3091242 0.933 rs61775174 chr1:25787313 G/A cg27572855 chr1:25598939 RHD -0.37 -7.9 -0.39 3.89e-14 Erythrocyte sedimentation rate; LIHC trans rs4332037 0.802 rs12113633 chr7:1932936 G/A cg11693508 chr17:37793320 STARD3 0.71 7.3 0.37 2e-12 Bipolar disorder; LIHC cis rs875971 0.895 rs10755833 chr7:65913917 A/G cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs57502260 0.704 rs72936570 chr11:68307139 A/G cg20283391 chr11:68216788 NA -0.51 -5.96 -0.31 6.27e-9 Total body bone mineral density (age 45-60); LIHC cis rs6684514 1.000 rs66965793 chr1:156285814 G/A cg16558208 chr1:156270281 VHLL 0.55 10.39 0.49 3.56e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs611744 0.967 rs686251 chr8:109198907 C/A cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 6.02e-17 Dupuytren's disease; LIHC cis rs10464366 0.544 rs1525799 chr7:39153131 C/G cg15212455 chr7:39170539 POU6F2 -0.47 -8.32 -0.41 2.05e-15 IgG glycosylation; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg10150615 chr22:24372951 LOC391322 -0.55 -7.9 -0.39 3.92e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12602486 1.000 rs60684277 chr17:42281307 G/A cg08193365 chr17:42277699 NA 0.97 6.64 0.34 1.23e-10 Glycated hemoglobin levels; LIHC cis rs1799949 1.000 rs8176318 chr17:41197274 G/T cg23758822 chr17:41437982 NA 0.83 14.89 0.63 5.27e-39 Menopause (age at onset); LIHC cis rs17666538 0.710 rs7834337 chr8:655828 A/G cg07234876 chr8:600039 NA 0.82 7.48 0.38 6.26e-13 IgG glycosylation; LIHC cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg01017244 chr2:74357527 NA 0.62 11.47 0.53 5.54e-26 Gestational age at birth (maternal effect); LIHC cis rs9581857 0.579 rs7332104 chr13:27957831 C/G cg22138327 chr13:27999177 GTF3A -0.72 -6.37 -0.33 6.2e-10 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs2412488 0.893 rs36011216 chr4:54350726 T/A cg22241045 chr4:54363911 LNX1 -0.43 -6.96 -0.35 1.7e-11 DNA methylation (variation); LIHC cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -5.99 -0.31 5.28e-9 Bipolar disorder and schizophrenia; LIHC cis rs4319547 0.956 rs7397990 chr12:123119472 T/C cg23029597 chr12:123009494 RSRC2 -0.49 -6.87 -0.35 3.14e-11 Body mass index; LIHC trans rs1005277 0.529 rs1780125 chr10:38531376 A/G cg27523141 chr10:43048294 ZNF37B 0.4 6.76 0.34 6.02e-11 Extrinsic epigenetic age acceleration; LIHC cis rs7412746 0.622 rs72704654 chr1:150826410 G/A cg15448220 chr1:150897856 SETDB1 0.39 5.8 0.3 1.55e-8 Melanoma; LIHC cis rs12701220 0.690 rs10243973 chr7:1064983 T/C cg00990874 chr7:1149470 C7orf50 -0.64 -9.01 -0.44 1.5e-17 Bronchopulmonary dysplasia; LIHC cis rs11920354 0.642 rs9812878 chr3:47182787 T/C cg27129171 chr3:47204927 SETD2 0.55 8.74 0.43 1.07e-16 Granulocyte count;Sum neutrophil eosinophil counts; LIHC cis rs1707322 0.717 rs3014237 chr1:46090252 A/G cg24296786 chr1:45957014 TESK2 0.41 5.76 0.3 1.85e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4332037 0.624 rs56256289 chr7:1892529 C/T cg23422044 chr7:1970798 MAD1L1 -0.55 -6.7 -0.34 8.61e-11 Bipolar disorder; LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.96 20.87 0.75 5.93e-63 Prudent dietary pattern; LIHC cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg25897951 chr4:1244024 CTBP1;C4orf42 -0.4 -5.71 -0.3 2.42e-8 Longevity; LIHC cis rs1005277 0.579 rs1780122 chr10:38529509 C/A cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.9 -0.3 8.56e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7107174 1.000 rs2510035 chr11:77953175 A/C cg02023728 chr11:77925099 USP35 0.49 9.3 0.45 1.68e-18 Testicular germ cell tumor; LIHC cis rs2228479 0.850 rs62052660 chr16:89847420 T/A cg06558623 chr16:89946397 TCF25 0.84 11.24 0.52 3.56e-25 Skin colour saturation; LIHC cis rs2637266 0.935 rs12259550 chr10:78352843 A/G cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs1461503 0.932 rs7944492 chr11:122838745 G/T cg14473756 chr11:122847823 NA -0.37 -6.65 -0.34 1.18e-10 Menarche (age at onset); LIHC cis rs516243 0.871 rs3748687 chr1:10736216 G/A cg02903756 chr1:10750680 CASZ1 -0.44 -7.47 -0.37 6.97e-13 Migraine - clinic-based; LIHC cis rs7829975 0.688 rs7817376 chr8:8380530 C/T cg15556689 chr8:8085844 FLJ10661 -0.36 -5.78 -0.3 1.7e-8 Mood instability; LIHC cis rs2933343 0.909 rs1683817 chr3:128651536 G/A cg25356066 chr3:128598488 ACAD9 0.52 6.84 0.35 3.62e-11 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14604386 chr6:119670882 MAN1A1 -0.43 -6.51 -0.33 2.7e-10 Cognitive function; LIHC cis rs10751667 0.666 rs7936830 chr11:959686 A/G cg06064525 chr11:970664 AP2A2 -0.56 -15.02 -0.63 1.64e-39 Alzheimer's disease (late onset); LIHC cis rs4820294 1.000 rs4820294 chr22:38071043 G/A cg00142150 chr22:38071001 LGALS1 0.71 11.5 0.53 4.34e-26 Fat distribution (HIV); LIHC cis rs4561483 0.734 rs33655 chr16:11970381 C/T cg08843971 chr16:11963173 GSPT1 -0.42 -8.56 -0.42 3.9e-16 Testicular germ cell tumor; LIHC cis rs5769765 0.646 rs9627789 chr22:50300562 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -8.96 -0.44 2.22e-17 Schizophrenia; LIHC cis rs651907 0.535 rs11711903 chr3:101500748 C/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.86 -0.3 1.09e-8 Colorectal cancer; LIHC cis rs3736485 0.934 rs882385 chr15:51882369 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10464366 0.746 rs6945402 chr7:39145385 A/T cg18850127 chr7:39170497 POU6F2 0.48 8.5 0.42 6e-16 IgG glycosylation; LIHC cis rs6430585 0.528 rs6750549 chr2:136707480 A/G cg25344623 chr2:136566232 LCT -0.37 -5.99 -0.31 5.2e-9 Corneal structure; LIHC cis rs10744422 1.000 rs937766 chr12:123331094 G/T cg07706471 chr12:123319906 HIP1R -0.62 -8.23 -0.41 4.12e-15 Schizophrenia; LIHC cis rs4906332 1.000 rs4906327 chr14:103929039 C/T cg04998671 chr14:104000505 TRMT61A -0.45 -6.18 -0.32 1.86e-9 Coronary artery disease; LIHC cis rs7267979 1.000 rs2257496 chr20:25279315 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7131987 0.845 rs7299861 chr12:29409667 G/A cg16970926 chr12:29381810 FAR2 0.32 6.8 0.34 4.75e-11 QT interval; LIHC cis rs1419980 0.673 rs12366473 chr12:7728270 G/C cg10578777 chr12:7781093 NA 0.47 8.23 0.41 3.87e-15 HDL cholesterol levels; LIHC cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg16606324 chr3:10149918 C3orf24 0.55 6.0 0.31 4.95e-9 Alzheimer's disease; LIHC cis rs7095607 0.606 rs7095774 chr10:69957554 C/T cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.94e-9 Lung function (FVC); LIHC cis rs9916302 0.752 rs6503513 chr17:37561613 A/G cg07936489 chr17:37558343 FBXL20 0.92 14.31 0.61 9.88e-37 Glomerular filtration rate (creatinine); LIHC cis rs950169 0.544 rs2036949 chr15:85163605 T/C cg12863693 chr15:85201151 NMB 0.5 7.22 0.36 3.42e-12 Schizophrenia; LIHC cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg16606324 chr3:10149918 C3orf24 0.52 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs1801251 0.929 rs12694917 chr2:233707611 C/T cg08000102 chr2:233561755 GIGYF2 -0.77 -11.64 -0.53 1.36e-26 Coronary artery disease; LIHC cis rs600806 0.751 rs1933182 chr1:109999838 A/C cg23091122 chr1:110024289 SYPL2 -0.52 -6.93 -0.35 2.04e-11 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.671 rs2591956 chr5:56244604 G/A cg24531977 chr5:56204891 C5orf35 0.52 7.47 0.37 6.66e-13 Initial pursuit acceleration; LIHC cis rs782590 0.967 rs11125579 chr2:55739804 T/C cg03859395 chr2:55845619 SMEK2 0.77 12.77 0.57 8.65e-31 Metabolic syndrome; LIHC cis rs6466055 0.639 rs11760317 chr7:104711711 T/C cg04380332 chr7:105027541 SRPK2 -0.33 -6.27 -0.32 1.11e-9 Schizophrenia; LIHC trans rs208520 0.874 rs208456 chr6:66907942 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.71 -7.69 -0.38 1.56e-13 Exhaled nitric oxide output; LIHC cis rs2304069 0.614 rs216140 chr5:149443298 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.59 7.95 0.4 2.67e-14 HIV-1 control; LIHC cis rs4665809 0.887 rs2384324 chr2:26354239 A/G cg27170947 chr2:26402098 FAM59B -0.69 -8.65 -0.42 2.07e-16 Gut microbiome composition (summer); LIHC cis rs6546550 0.935 rs3771541 chr2:70031797 C/G cg02498382 chr2:70120550 SNRNP27 -0.42 -6.77 -0.34 5.56e-11 Prevalent atrial fibrillation; LIHC cis rs7582720 0.887 rs72934589 chr2:204017937 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.1 -0.31 2.91e-9 Total body bone mineral density; LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg07092213 chr7:1199455 ZFAND2A -0.45 -6.78 -0.34 5.41e-11 Longevity;Endometriosis; LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.5 -0.38 5.37e-13 Lymphocyte counts; LIHC cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.35 -0.45 1.2e-18 Bipolar disorder; LIHC cis rs2180341 1.000 rs4895822 chr6:127642703 T/C cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs34330 0.562 rs10492235 chr12:12851339 T/G cg09462578 chr12:12878428 APOLD1 -0.78 -10.2 -0.48 1.68e-21 Systemic lupus erythematosus; LIHC cis rs35146811 0.807 rs6953441 chr7:99617067 G/A cg22906224 chr7:99728672 NA 0.45 6.41 0.33 4.71e-10 Coronary artery disease; LIHC cis rs986417 0.818 rs2351173 chr14:61008755 C/T cg27398547 chr14:60952738 C14orf39 0.73 8.29 0.41 2.61e-15 Gut microbiota (bacterial taxa); LIHC cis rs57920188 0.584 rs10915654 chr1:4091419 C/A cg20703997 chr1:4087676 NA 0.51 6.09 0.31 3.11e-9 Interleukin-17 levels; LIHC cis rs5769765 0.773 rs9616383 chr22:50313014 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs11577318 0.853 rs12743998 chr1:26629882 G/A cg10402321 chr1:26617780 UBXN11 -0.38 -5.8 -0.3 1.48e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg05564831 chr3:52568323 NT5DC2 0.36 5.85 0.3 1.12e-8 Bipolar disorder; LIHC cis rs826838 0.967 rs10875979 chr12:39095149 G/A cg26384229 chr12:38710491 ALG10B 0.72 9.71 0.46 7.44e-20 Heart rate; LIHC cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg04944784 chr2:26401820 FAM59B 0.74 9.03 0.44 1.26e-17 Gut microbiome composition (summer); LIHC cis rs9660992 0.710 rs1668869 chr1:205239779 G/C cg21545522 chr1:205238299 TMCC2 0.42 8.03 0.4 1.54e-14 Mean corpuscular volume;Mean platelet volume; LIHC cis rs514406 0.570 rs1332776 chr1:53189816 C/T cg16325326 chr1:53192061 ZYG11B 0.54 9.41 0.45 7.45e-19 Monocyte count; LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.39 0.8 7.99e-77 Prudent dietary pattern; LIHC cis rs921968 0.509 rs832813 chr2:219354569 T/C cg02176678 chr2:219576539 TTLL4 0.51 7.12 0.36 6.59e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs10256972 0.900 rs7812072 chr7:1053862 A/G cg23978390 chr7:1156363 C7orf50 0.52 7.77 0.39 9.45e-14 Longevity;Endometriosis; LIHC cis rs35146811 0.555 rs1981549 chr7:99541636 A/G cg19636519 chr7:99541626 NA 0.31 6.22 0.32 1.47e-9 Coronary artery disease; LIHC cis rs1707322 0.717 rs3014245 chr1:46086913 C/T cg06784218 chr1:46089804 CCDC17 -0.43 -7.89 -0.39 4.18e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs747782 0.702 rs17790804 chr11:47447202 T/C cg20307385 chr11:47447363 PSMC3 -0.54 -5.76 -0.3 1.84e-8 Intraocular pressure; LIHC cis rs10751667 0.666 rs7395267 chr11:962326 C/A cg06064525 chr11:970664 AP2A2 -0.56 -14.83 -0.63 9.18e-39 Alzheimer's disease (late onset); LIHC cis rs8083850 0.635 rs1897261 chr18:50851974 A/G cg24270629 chr18:50823537 DCC 0.53 7.97 0.4 2.39e-14 Intelligence (multi-trait analysis); LIHC cis rs1904096 0.506 rs6841121 chr4:95222995 G/A cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.0 -0.44 1.54e-17 Type 2 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12738264 chr7:148725795 PDIA4 0.34 6.06 0.31 3.6e-9 Cognitive function; LIHC cis rs174601 0.864 rs174545 chr11:61569306 C/G cg27386326 chr11:61587980 NA 0.7 14.82 0.63 9.56e-39 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg08280861 chr8:58055591 NA 0.52 6.25 0.32 1.22e-9 Developmental language disorder (linguistic errors); LIHC cis rs1401999 0.966 rs2139560 chr3:183653869 A/G cg01324343 chr3:183735012 ABCC5 0.74 12.15 0.55 1.71e-28 Anterior chamber depth; LIHC cis rs61041384 0.661 rs7967118 chr12:123571503 C/G cg00376283 chr12:123451042 ABCB9 -0.6 -5.72 -0.3 2.27e-8 Schizophrenia; LIHC cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs2933343 0.951 rs789217 chr3:128593201 C/T cg25356066 chr3:128598488 ACAD9 0.56 7.28 0.37 2.31e-12 IgG glycosylation; LIHC cis rs9534288 0.797 rs1319712 chr13:46591707 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs909002 1.000 rs1474182 chr1:32136398 C/T cg13919466 chr1:32135498 COL16A1 -0.37 -7.1 -0.36 7.47e-12 Intelligence (multi-trait analysis); LIHC trans rs208520 0.507 rs7755710 chr6:66783355 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.05 -20.19 -0.74 3.18e-60 Exhaled nitric oxide output; LIHC trans rs916888 0.610 rs199438 chr17:44791643 G/A cg22968622 chr17:43663579 NA 0.49 7.1 0.36 7.39e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs2235573 0.517 rs4821727 chr22:38393423 C/A cg19894588 chr14:64061835 NA 0.49 6.66 0.34 1.1e-10 Glioblastoma;Glioma; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg14967899 chr8:26434689 DPYSL2 -0.44 -6.28 -0.32 1.02e-9 Triglycerides; LIHC cis rs9918079 0.560 rs6414767 chr4:15655721 A/G cg16509355 chr4:15471240 CC2D2A -0.47 -7.21 -0.36 3.51e-12 Obesity-related traits; LIHC cis rs317689 0.684 rs315125 chr12:69758884 C/T cg19645103 chr12:69753606 YEATS4 -0.46 -6.28 -0.32 1.04e-9 Response to diuretic therapy; LIHC cis rs858239 0.636 rs7808488 chr7:23221870 T/C cg18081818 chr7:23246105 NA -0.46 -7.03 -0.36 1.13e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs7119038 0.580 rs7123726 chr11:118694547 T/C cg19308663 chr11:118741387 NA 0.4 6.14 0.32 2.27e-9 Sjögren's syndrome; LIHC cis rs2963155 0.518 rs2918419 chr5:142722353 T/C cg17617527 chr5:142782415 NR3C1 0.9 10.56 0.5 9.71e-23 Breast cancer; LIHC cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg02969873 chr4:1330999 MAEA -0.42 -6.54 -0.33 2.2e-10 Longevity; LIHC cis rs611744 0.967 rs645070 chr8:109216345 A/C cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.74e-17 Dupuytren's disease; LIHC cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.16 0.44 4.84e-18 Bipolar disorder; LIHC cis rs2637266 0.783 rs58247832 chr10:78471383 C/A cg18941641 chr10:78392320 NA 0.27 5.86 0.3 1.11e-8 Pulmonary function; LIHC cis rs2952156 0.876 rs903501 chr17:37839493 T/C cg00129232 chr17:37814104 STARD3 -0.53 -9.76 -0.47 5e-20 Asthma; LIHC cis rs12477438 0.520 rs13004491 chr2:99738008 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.53 0.64 1.5e-41 Chronic sinus infection; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03009463 chr7:17980271 SNX13 -0.52 -6.06 -0.31 3.53e-9 Systolic blood pressure; LIHC cis rs892961 0.932 rs7216116 chr17:75405078 C/T cg01320579 chr17:75405842 SEPT9 0.54 7.09 0.36 7.62e-12 Airflow obstruction; LIHC cis rs6933660 0.665 rs6921042 chr6:151732385 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.66 11.14 0.52 8.37e-25 Menarche (age at onset); LIHC cis rs6502050 0.835 rs6502070 chr17:80112634 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.98 -0.31 5.54e-9 Life satisfaction; LIHC cis rs365132 0.934 rs183686 chr5:176494102 A/G cg16309518 chr5:176445507 NA -0.57 -10.7 -0.5 3.06e-23 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs11630290 0.592 rs11634436 chr15:64158394 T/G cg12036633 chr15:63758958 NA 0.61 6.55 0.33 2.08e-10 Iris characteristics; LIHC trans rs1005277 0.579 rs176880 chr10:38401417 C/G cg27523141 chr10:43048294 ZNF37B -0.37 -6.36 -0.33 6.37e-10 Extrinsic epigenetic age acceleration; LIHC cis rs735396 0.770 rs2259820 chr12:121435342 C/T cg25281562 chr12:121454272 C12orf43 0.36 6.27 0.32 1.06e-9 N-glycan levels; LIHC cis rs7647973 0.593 rs1799844 chr3:49847642 G/A cg03060546 chr3:49711283 APEH -0.55 -6.07 -0.31 3.49e-9 Menarche (age at onset); LIHC cis rs3784262 1.000 rs12903474 chr15:58276747 A/C cg12031962 chr15:58353849 ALDH1A2 0.33 6.36 0.33 6.42e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg08975724 chr8:8085496 FLJ10661 0.43 7.0 0.35 1.39e-11 Systolic blood pressure; LIHC cis rs919433 0.963 rs12693815 chr2:198168403 T/C cg03934865 chr2:198174659 NA -0.57 -9.01 -0.44 1.51e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs875971 0.571 rs160641 chr7:65577346 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.38 -7.54 -0.38 4.25e-13 Aortic root size; LIHC cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9388451 0.839 rs3799709 chr6:126078361 A/G cg05901451 chr6:126070800 HEY2 -0.76 -18.09 -0.7 8.59e-52 Brugada syndrome; LIHC cis rs72772090 0.908 rs72772091 chr5:96040122 C/A cg17330273 chr5:96107758 CAST;ERAP1 -0.57 -6.53 -0.33 2.37e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs3106136 0.967 rs2664892 chr4:95154186 T/C cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.76 -0.39 9.64e-14 Capecitabine sensitivity; LIHC cis rs12079745 1.000 rs74967728 chr1:169202731 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -7.09 -0.36 7.82e-12 QT interval; LIHC cis rs9303401 0.659 rs35828828 chr17:56718205 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 8.81 0.43 6.41e-17 Cognitive test performance; LIHC cis rs6933660 0.683 rs8180642 chr6:151756612 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.49 -7.41 -0.37 1e-12 Menarche (age at onset); LIHC cis rs738322 0.555 rs6001027 chr22:38545619 A/G cg25457927 chr22:38595422 NA -0.39 -9.36 -0.45 1.06e-18 Cutaneous nevi; LIHC cis rs16958440 1.000 rs16958440 chr18:44632884 C/G cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg24884572 chr19:58661833 ZNF329 0.96 7.48 0.37 6.44e-13 Cholesterol, total; LIHC cis rs4407350 0.721 rs105248 chr22:44891399 C/G cg11695653 chr22:44894386 LDOC1L -0.38 -6.54 -0.33 2.23e-10 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.765 rs2628185 chr17:28070107 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.47 -0.59 1.77e-33 Coffee consumption (cups per day); LIHC cis rs7296418 0.961 rs1790106 chr12:123591596 G/T cg06742321 chr12:123595122 PITPNM2 0.31 5.84 0.3 1.25e-8 Platelet count; LIHC trans rs1005277 0.602 rs1831315 chr10:38473353 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.25 -0.32 1.2e-9 Extrinsic epigenetic age acceleration; LIHC cis rs67311347 1.000 rs56992941 chr3:40472434 A/T cg00656387 chr3:40428638 ENTPD3 0.44 7.45 0.37 7.71e-13 Renal cell carcinoma; LIHC cis rs986417 0.818 rs2092722 chr14:61062890 T/A cg27398547 chr14:60952738 C14orf39 0.49 5.88 0.3 9.67e-9 Gut microbiota (bacterial taxa); LIHC cis rs754466 0.606 rs11002309 chr10:79594931 C/T cg17075019 chr10:79541650 NA -0.78 -12.09 -0.55 3.05e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7131987 0.868 rs11050151 chr12:29403008 T/A cg00204748 chr12:29376779 FAR2 0.44 8.53 0.42 4.83e-16 QT interval; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14077301 chr14:58766370 ARID4A 0.47 6.37 0.33 6.18e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs782590 0.764 rs935177 chr2:55826761 C/G cg03859395 chr2:55845619 SMEK2 0.72 11.75 0.54 5.37e-27 Metabolic syndrome; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12357364 chr17:1557144 PRPF8 0.44 6.19 0.32 1.7e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg14257396 chr1:107603778 NA 0.35 5.72 0.3 2.33e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs16828019 0.852 rs12406620 chr1:41512664 A/T cg03387723 chr1:41708464 SCMH1 -0.41 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs6456156 0.586 rs2001114 chr6:167486578 A/G cg23791538 chr6:167370224 RNASET2 -0.55 -8.6 -0.42 2.88e-16 Primary biliary cholangitis; LIHC cis rs11758351 1.000 rs17598927 chr6:26184640 C/G cg03854865 chr6:26224070 HIST1H3E -0.7 -7.74 -0.39 1.16e-13 Gout;Renal underexcretion gout; LIHC cis rs4780401 0.933 rs1579258 chr16:11824903 C/G cg01061890 chr16:11836724 TXNDC11 -0.4 -5.87 -0.3 1.05e-8 Rheumatoid arthritis; LIHC cis rs910316 0.737 rs28687415 chr14:75495482 T/C cg08847533 chr14:75593920 NEK9 0.89 18.09 0.7 8.88e-52 Height; LIHC cis rs7909074 0.509 rs2026427 chr10:45389704 T/C cg04218760 chr10:45406644 TMEM72 -0.21 -6.27 -0.32 1.06e-9 Mean corpuscular volume; LIHC cis rs2710642 0.525 rs1601673 chr2:62842559 G/C cg17519650 chr2:63277830 OTX1 0.46 7.29 0.37 2.19e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg12016809 chr21:47604291 C21orf56 0.45 6.59 0.34 1.63e-10 Testicular germ cell tumor; LIHC cis rs7216064 1.000 rs7214758 chr17:65880538 T/C cg12091567 chr17:66097778 LOC651250 -0.67 -9.33 -0.45 1.32e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7833986 0.501 rs72653941 chr8:56942247 T/C cg23139584 chr8:56987506 RPS20;SNORD54 0.74 7.79 0.39 8.16e-14 Height; LIHC cis rs208346 1.000 rs208346 chr7:2799686 G/T cg18446336 chr7:2847575 GNA12 0.35 6.94 0.35 1.95e-11 Loneliness (linear analysis); LIHC cis rs427394 0.659 rs274678 chr5:6752385 A/G cg10857441 chr5:6722123 POLS 0.39 6.64 0.34 1.2e-10 Menopause (age at onset); LIHC cis rs597539 0.652 rs602364 chr11:68662167 C/T cg06028808 chr11:68637592 NA 0.43 5.73 0.3 2.22e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs66887589 0.748 rs28439855 chr4:120262256 G/A cg25214090 chr10:38739885 LOC399744 0.4 6.8 0.35 4.74e-11 Diastolic blood pressure; LIHC cis rs9814567 1.000 rs4334685 chr3:134304335 T/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.45e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs539514 0.501 rs8000656 chr13:76400640 A/G cg04757411 chr13:76259545 LMO7 0.38 5.99 0.31 5.29e-9 Type 1 diabetes; LIHC cis rs5769707 0.609 rs739247 chr22:49996657 T/C cg07959070 chr22:50026188 C22orf34 -0.33 -8.01 -0.4 1.88e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs78456975 1.000 rs10192959 chr2:1553393 G/T cg01028140 chr2:1542097 TPO -0.56 -6.64 -0.34 1.27e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs11785400 0.793 rs11543967 chr8:143739435 A/G cg24634471 chr8:143751801 JRK -0.48 -7.38 -0.37 1.22e-12 Schizophrenia; LIHC cis rs2073300 1.000 rs6114141 chr20:23460620 T/G cg12062639 chr20:23401060 NAPB 0.79 9.93 0.47 1.36e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7614311 0.681 rs73119022 chr3:63979834 T/C cg22134162 chr3:63841271 THOC7 -0.53 -5.85 -0.3 1.15e-8 Lung function (FVC);Lung function (FEV1); LIHC cis rs8180040 0.676 rs1108301 chr3:47029426 G/A cg16586182 chr3:47516702 SCAP 0.47 8.14 0.4 7.42e-15 Colorectal cancer; LIHC cis rs12286929 0.583 rs10458966 chr11:115102758 T/C cg04055981 chr11:115044050 NA 0.38 5.83 0.3 1.32e-8 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6545883 0.929 rs778140 chr2:61682976 C/T cg15711740 chr2:61764176 XPO1 -0.42 -5.82 -0.3 1.34e-8 Tuberculosis; LIHC cis rs1878931 0.582 rs27227 chr16:3429778 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.78 -0.43 8.05e-17 Body mass index (adult); LIHC cis rs2404602 0.647 rs36114653 chr15:77025393 G/A cg23625390 chr15:77176239 SCAPER -0.52 -8.59 -0.42 3.15e-16 Blood metabolite levels; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg18279126 chr7:2041391 MAD1L1 0.39 6.51 0.33 2.74e-10 Bipolar disorder and schizophrenia; LIHC cis rs9814567 1.000 rs9851441 chr3:134315091 C/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.34e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs826838 1.000 rs11168367 chr12:38913397 T/G cg26384229 chr12:38710491 ALG10B 0.97 13.1 0.58 4.65e-32 Heart rate; LIHC cis rs8180040 0.726 rs1463393 chr3:46994987 G/A cg27129171 chr3:47204927 SETD2 -0.63 -10.74 -0.5 2.17e-23 Colorectal cancer; LIHC cis rs4319547 0.695 rs4758666 chr12:122902840 C/T cg23029597 chr12:123009494 RSRC2 -0.53 -7.56 -0.38 3.83e-13 Body mass index; LIHC cis rs3736485 0.903 rs9944241 chr15:51898058 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs7714584 1.000 rs2345001 chr5:150266518 G/T cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC trans rs1945213 0.694 rs7116741 chr11:55862620 C/T cg03929089 chr4:120376271 NA 0.53 6.87 0.35 3.01e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs4713118 0.955 rs9380010 chr6:27683572 A/G cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC cis rs7605378 0.752 rs769960 chr2:200710706 G/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.49 -6.35 -0.32 6.82e-10 Osteoporosis; LIHC cis rs1577917 0.958 rs12196175 chr6:86779370 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.04 -0.48 5.98e-21 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs1360054 chr6:8520377 C/A cg21535247 chr6:8435926 SLC35B3 0.63 8.31 0.41 2.3e-15 Motion sickness; LIHC cis rs1816752 0.870 rs9318529 chr13:24998328 A/G cg02811702 chr13:24901961 NA 0.23 5.76 0.3 1.89e-8 Obesity-related traits; LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.98 -0.31 5.5e-9 Total body bone mineral density; LIHC cis rs6964587 1.000 rs10225892 chr7:91671020 A/G cg17063962 chr7:91808500 NA 1.03 20.74 0.75 1.91e-62 Breast cancer; LIHC cis rs847649 0.548 rs10953380 chr7:102747149 C/G cg18108683 chr7:102477205 FBXL13 0.41 6.32 0.32 8.13e-10 Morning vs. evening chronotype; LIHC trans rs11722228 0.522 rs73212880 chr4:10115692 T/A cg26043149 chr18:55253948 FECH 0.96 13.84 0.6 6.82e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs35110281 0.776 rs1073522 chr21:45009219 T/A cg04455712 chr21:45112962 RRP1B 0.47 7.9 0.39 3.95e-14 Mean corpuscular volume; LIHC cis rs3806843 0.735 rs801188 chr5:140066916 G/T cg19875535 chr5:140030758 IK -0.41 -6.65 -0.34 1.14e-10 Depressive symptoms (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26294578 chr17:79319535 NA 0.42 6.12 0.31 2.54e-9 Pancreatic cancer; LIHC cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.26 -0.61 1.61e-36 Alzheimer's disease; LIHC cis rs6570726 0.935 rs430561 chr6:145813140 C/T cg23711669 chr6:146136114 FBXO30 0.55 9.76 0.47 5.21e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 1.000 rs1478565 chr3:161027464 C/T cg03342759 chr3:160939853 NMD3 -0.72 -8.78 -0.43 7.96e-17 Morning vs. evening chronotype; LIHC cis rs765787 0.530 rs11636367 chr15:45535862 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs600626 0.529 rs59913369 chr11:75473265 A/G cg24262691 chr11:75473276 NA 0.44 6.49 0.33 2.94e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs7613875 0.600 rs7061 chr3:50114515 C/T cg21467203 chr3:49911342 NA 0.52 9.5 0.46 3.72e-19 Body mass index; LIHC cis rs12474201 0.925 rs1058157 chr2:46988275 G/A cg06386533 chr2:46925753 SOCS5 0.72 8.1 0.4 9.78e-15 Height; LIHC cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg23978390 chr7:1156363 C7orf50 0.43 6.52 0.33 2.59e-10 Longevity;Endometriosis; LIHC cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg20295408 chr7:1910781 MAD1L1 -0.46 -6.86 -0.35 3.3e-11 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC cis rs765787 0.556 rs2413778 chr15:45539397 C/A cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC cis rs875971 0.545 rs73148639 chr7:65855329 A/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.1 0.36 7.27e-12 Aortic root size; LIHC cis rs2050392 0.624 rs303444 chr10:30729347 C/T cg25182066 chr10:30743637 MAP3K8 -0.61 -9.72 -0.47 7.19e-20 Inflammatory bowel disease; LIHC cis rs7586673 0.893 rs889925 chr2:161971597 T/C cg08807892 chr2:162101083 NA 0.36 5.83 0.3 1.28e-8 Intelligence (multi-trait analysis); LIHC cis rs17106184 1.000 rs72902726 chr1:51223500 T/C cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs7534824 0.625 rs61780331 chr1:101480610 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.68 6.74 0.34 6.76e-11 Refractive astigmatism; LIHC cis rs2230307 0.536 rs834278 chr1:100510882 T/C cg24955406 chr1:100503596 HIAT1 0.62 6.14 0.32 2.27e-9 Carotid intima media thickness; LIHC cis rs2607426 0.681 rs2233153 chr19:41281106 G/C cg20631044 chr19:41255890 C19orf54;SNRPA -0.54 -6.02 -0.31 4.59e-9 Blood protein levels; LIHC cis rs66573146 0.656 rs66905212 chr4:6949508 G/C cg00086871 chr4:6988644 TBC1D14 0.89 6.27 0.32 1.07e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2549003 0.933 rs7719499 chr5:131814091 C/G cg21138405 chr5:131827807 IRF1 0.35 8.76 0.43 8.91e-17 Asthma (sex interaction); LIHC cis rs68092024 0.704 rs704575 chr3:99486075 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.91 0.3 8.09e-9 Cleft lip with or without cleft palate; LIHC cis rs858239 0.539 rs2141305 chr7:23191899 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.83 0.35 3.89e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2286503 0.780 rs2286506 chr7:22854815 T/C cg11367502 chr7:22862612 TOMM7 0.47 8.14 0.4 7.59e-15 Fibrinogen; LIHC cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.628 rs4474733 chr17:41433660 G/T cg10360323 chr17:41437877 NA 0.42 6.12 0.31 2.53e-9 Menopause (age at onset); LIHC cis rs2933343 0.729 rs789230 chr3:128602558 G/A cg25356066 chr3:128598488 ACAD9 0.55 7.7 0.38 1.51e-13 IgG glycosylation; LIHC cis rs919433 0.713 rs55642934 chr2:198491110 C/T cg03934865 chr2:198174659 NA 0.51 7.55 0.38 3.92e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs611744 0.967 rs650401 chr8:109196854 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs2236918 1.000 rs2526701 chr1:242018427 T/C cg17736920 chr1:242011382 EXO1 0.61 9.18 0.44 4.16e-18 Menopause (age at onset); LIHC cis rs61990749 0.597 rs1048147 chr14:78139988 C/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.18 -0.48 1.9e-21 Fibroblast growth factor basic levels; LIHC cis rs6546550 0.901 rs6750488 chr2:70146125 C/T cg02498382 chr2:70120550 SNRNP27 -0.44 -7.62 -0.38 2.57e-13 Prevalent atrial fibrillation; LIHC cis rs1371867 0.846 rs1660351 chr8:101275034 C/T cg06636551 chr8:101224915 SPAG1 -0.51 -9.56 -0.46 2.42e-19 Atrioventricular conduction; LIHC cis rs6120849 0.754 rs3746446 chr20:33574765 T/C cg24642439 chr20:33292090 TP53INP2 0.65 7.18 0.36 4.25e-12 Protein C levels; LIHC cis rs798554 0.679 rs798499 chr7:2792013 G/A cg13628971 chr7:2884303 GNA12 0.4 6.36 0.33 6.63e-10 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23409613 chr14:53196849 STYX -0.35 -6.16 -0.32 2.08e-9 Pancreatic cancer; LIHC cis rs2380220 1.000 rs2380220 chr6:95967412 T/C cg04719120 chr6:96025338 MANEA 0.66 5.93 0.31 7.49e-9 Behavioural disinhibition (generation interaction); LIHC cis rs34172651 0.917 rs2059134 chr16:24816492 C/T cg04756594 chr16:24857601 SLC5A11 -0.43 -6.91 -0.35 2.35e-11 Intelligence (multi-trait analysis); LIHC cis rs8103278 1.000 rs725660 chr19:46262286 C/A cg14061069 chr19:46274453 DMPK -0.58 -9.27 -0.45 2.1e-18 Coronary artery disease; LIHC cis rs1577917 0.958 rs12195776 chr6:86488599 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.7 -0.38 1.5e-13 Response to antipsychotic treatment; LIHC cis rs2953174 0.786 rs2953146 chr2:241515252 A/G cg07929629 chr2:241523174 NA -0.55 -6.71 -0.34 8.3e-11 Bipolar disorder; LIHC cis rs1355223 1.000 rs1396879 chr11:34766653 A/C cg11058730 chr11:34937778 PDHX;APIP -0.47 -6.44 -0.33 4.05e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6988636 1.000 rs7002332 chr8:124185442 G/C cg15893493 chr8:124194847 FAM83A 0.89 8.3 0.41 2.48e-15 Urinary uromodulin levels; LIHC cis rs35110281 0.720 rs162400 chr21:44950305 A/C cg01579765 chr21:45077557 HSF2BP -0.34 -6.11 -0.31 2.73e-9 Mean corpuscular volume; LIHC cis rs1059312 1.000 rs9738216 chr12:129281788 C/T cg09035930 chr12:129282057 SLC15A4 0.67 12.89 0.57 2.87e-31 Systemic lupus erythematosus; LIHC cis rs6952808 0.693 rs10950413 chr7:1912988 A/G cg21782813 chr7:2030301 MAD1L1 0.42 6.96 0.35 1.73e-11 Bipolar disorder and schizophrenia; LIHC cis rs36051895 0.502 rs10975003 chr9:5213687 T/C cg02405213 chr9:5042618 JAK2 -0.61 -10.1 -0.48 3.53e-21 Pediatric autoimmune diseases; LIHC cis rs7917772 0.636 rs2249850 chr10:104512006 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.57 6.7 0.34 8.64e-11 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11098499 0.908 rs11729050 chr4:120300066 T/C cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs2658782 0.547 rs3133454 chr11:93059019 A/C cg15737290 chr11:93063684 CCDC67 0.46 6.01 0.31 4.8e-9 Pulmonary function decline; LIHC cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg13393036 chr8:95962371 TP53INP1 -0.4 -8.19 -0.41 5.14e-15 Type 2 diabetes; LIHC cis rs7618501 0.521 rs34654589 chr3:49911449 C/G cg24110177 chr3:50126178 RBM5 -0.55 -8.46 -0.42 7.96e-16 Intelligence (multi-trait analysis); LIHC cis rs9534288 0.797 rs4142548 chr13:46535350 A/G cg15192986 chr13:46630673 CPB2 -0.55 -8.44 -0.42 9.24e-16 Blood protein levels; LIHC trans rs11098499 0.954 rs3733519 chr4:120423448 A/G cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs2439831 0.850 rs2957637 chr15:43951118 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.57 7.12 0.36 6.22e-12 Lung cancer in ever smokers; LIHC cis rs17253792 0.732 rs10146604 chr14:56045770 C/G cg01858014 chr14:56050164 KTN1 -0.74 -8.03 -0.4 1.61e-14 Putamen volume; LIHC cis rs67981189 0.593 rs116016 chr14:71577480 G/A cg15816911 chr14:71606274 NA -0.42 -6.74 -0.34 6.65e-11 Schizophrenia; LIHC cis rs700651 0.789 rs1978889 chr2:198889366 G/A cg10820045 chr2:198174542 NA 0.43 6.51 0.33 2.64e-10 Intracranial aneurysm; LIHC cis rs79976124 0.879 rs17432710 chr6:66621744 T/C cg07460842 chr6:66804631 NA 0.64 6.68 0.34 9.96e-11 Type 2 diabetes; LIHC cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2842992 0.513 rs7759086 chr6:160193853 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.66 12.21 0.55 1.05e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs57677839 1 rs57677839 chr11:17028189 G/A cg15378786 chr11:17036137 PLEKHA7 0.95 14.18 0.61 3.07e-36 Coronary artery disease; LIHC cis rs13392177 0.684 rs11695527 chr2:219068103 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.57 8.06 0.4 1.32e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs753778 0.667 rs10103731 chr8:142206068 C/T cg18755752 chr8:142205143 DENND3 -0.32 -5.8 -0.3 1.5e-8 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs6500602 0.727 rs8051389 chr16:4570570 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 6.12 0.31 2.61e-9 Schizophrenia; LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg08219700 chr8:58056026 NA -0.57 -6.94 -0.35 1.99e-11 Developmental language disorder (linguistic errors); LIHC trans rs7618501 1.000 rs9872864 chr3:49792023 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.81 -0.63 1.14e-38 Intelligence (multi-trait analysis); LIHC trans rs11088226 0.681 rs9622 chr21:33951068 T/C cg09050820 chr6:167586206 TCP10L2 0.89 15.25 0.64 1.96e-40 Gastritis; LIHC cis rs17001868 0.568 rs6001894 chr22:40779197 T/C cg07138101 chr22:40742427 ADSL 0.56 6.52 0.33 2.55e-10 Mammographic density (dense area); LIHC cis rs10876993 0.928 rs2640636 chr12:58077544 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.25 -0.32 1.23e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs9470366 0.848 rs9470361 chr6:36623379 G/A cg08179530 chr6:36648295 CDKN1A 0.57 7.0 0.35 1.39e-11 QRS duration; LIHC cis rs10751667 0.643 rs7396767 chr11:938808 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.87 -0.63 6.47e-39 Alzheimer's disease (late onset); LIHC cis rs3780378 0.875 rs7861599 chr9:5067298 C/T cg02405213 chr9:5042618 JAK2 -0.51 -9.14 -0.44 5.58e-18 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg02187348 chr16:89574699 SPG7 0.67 10.56 0.5 9.29e-23 Multiple myeloma (IgH translocation); LIHC cis rs3820068 0.705 rs11584209 chr1:15885041 G/T cg17385448 chr1:15911702 AGMAT 0.4 6.44 0.33 4.15e-10 Systolic blood pressure; LIHC cis rs875971 0.638 rs10278816 chr7:66036987 T/C cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs7927592 0.913 rs7118897 chr11:68360680 G/A cg16797656 chr11:68205561 LRP5 0.52 8.3 0.41 2.43e-15 Total body bone mineral density; LIHC cis rs918629 0.761 rs17085333 chr5:95280848 A/T cg10483112 chr5:95245456 ELL2 0.36 6.07 0.31 3.41e-9 IgG glycosylation; LIHC cis rs8014204 0.762 rs10148293 chr14:75296831 C/T cg08847533 chr14:75593920 NEK9 -0.35 -5.92 -0.3 7.87e-9 Caffeine consumption; LIHC cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg16049864 chr8:95962084 TP53INP1 -0.64 -12.08 -0.55 3.12e-28 Type 2 diabetes; LIHC cis rs796364 0.806 rs56216998 chr2:200944333 G/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.65 -7.25 -0.37 2.75e-12 Schizophrenia; LIHC cis rs3806843 0.568 rs2530232 chr5:140082878 A/G cg16179182 chr5:140090404 VTRNA1-1 0.37 6.04 0.31 3.98e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs12220238 1.000 rs2279648 chr10:75867193 G/T cg19889307 chr10:75911429 ADK;AP3M1 0.71 6.94 0.35 1.98e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg23978390 chr7:1156363 C7orf50 0.54 7.89 0.39 4.03e-14 Longevity;Endometriosis; LIHC cis rs9916302 0.904 rs8076494 chr17:37516722 A/G cg00129232 chr17:37814104 STARD3 0.4 6.43 0.33 4.27e-10 Glomerular filtration rate (creatinine); LIHC cis rs11864453 0.614 rs12445586 chr16:72126276 C/T cg01557791 chr16:72042693 DHODH -0.47 -7.62 -0.38 2.58e-13 Fibrinogen levels; LIHC cis rs7927771 0.965 rs34958982 chr11:47547046 T/C cg18512352 chr11:47633146 NA -0.26 -6.13 -0.31 2.47e-9 Subjective well-being; LIHC cis rs8062405 0.754 rs3859172 chr16:28566158 G/T cg00204512 chr16:28754710 NA 0.34 6.95 0.35 1.86e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs5751150 1 rs5751150 chr22:42153292 T/G cg06634786 chr22:41940651 POLR3H 0.76 7.78 0.39 8.47e-14 Cannabis dependence symptom count; LIHC cis rs801193 0.839 rs6968619 chr7:66068867 T/C cg11764359 chr7:65958608 NA -0.62 -9.43 -0.45 6.37e-19 Aortic root size; LIHC cis rs11190604 0.767 rs3750723 chr10:102172989 T/C cg07080220 chr10:102295463 HIF1AN 0.44 6.02 0.31 4.49e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs35110281 0.837 rs12627667 chr21:45071396 A/C cg04455712 chr21:45112962 RRP1B 0.45 7.8 0.39 7.6e-14 Mean corpuscular volume; LIHC cis rs2839186 0.967 rs4819222 chr21:47707778 G/A cg12016809 chr21:47604291 C21orf56 0.43 6.27 0.32 1.11e-9 Testicular germ cell tumor; LIHC cis rs9309473 1.000 rs7594511 chr2:73681639 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.64 -0.34 1.22e-10 Metabolite levels; LIHC cis rs7212590 0.581 rs8081710 chr17:57838040 G/A cg10252138 chr17:58120427 NA -0.59 -5.88 -0.3 9.59e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs34779708 0.931 rs58159560 chr10:35351249 C/T cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.4e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs5769765 0.955 rs5769761 chr22:50263641 G/T cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16517634 chr2:8977876 KIDINS220 -0.46 -6.56 -0.33 1.97e-10 Pancreatic cancer; LIHC cis rs7959452 0.535 rs11615712 chr12:69619736 A/T cg22834771 chr12:69754056 YEATS4 0.45 7.92 0.39 3.3e-14 Blood protein levels; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.64 -0.42 2.21e-16 Lymphocyte counts; LIHC cis rs10791097 0.568 rs4411284 chr11:130738568 A/C cg14779329 chr11:130786720 SNX19 0.4 6.03 0.31 4.22e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs2681424 1.000 rs12488766 chr3:121757789 C/G cg03946530 chr15:65596423 NA 0.47 6.04 0.31 4.04e-9 Multiple sclerosis; LIHC cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg04267008 chr7:1944627 MAD1L1 -0.7 -10.87 -0.51 7.47e-24 Bipolar disorder and schizophrenia; LIHC cis rs4934494 0.768 rs12571268 chr10:91458587 T/C cg19698084 chr10:91461284 KIF20B -0.49 -6.47 -0.33 3.39e-10 Red blood cell count; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg03874509 chr1:107600012 PRMT6 -0.78 -12.44 -0.56 1.4e-29 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs896854 0.967 rs896853 chr8:95960855 G/C cg09323728 chr8:95962352 TP53INP1 -0.35 -7.75 -0.39 1.03e-13 Type 2 diabetes; LIHC cis rs769267 0.965 rs2023882 chr19:19405405 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.14e-9 Tonsillectomy; LIHC cis rs10489202 0.608 rs10918827 chr1:168077044 A/G cg24449463 chr1:168025552 DCAF6 0.51 7.77 0.39 9.43e-14 Schizophrenia; LIHC cis rs7224685 0.569 rs2123841 chr17:4022557 G/C cg09695851 chr17:3907499 NA 0.61 7.15 0.36 5.42e-12 Type 2 diabetes; LIHC cis rs4474465 1.000 rs10899523 chr11:78190808 C/T cg27205649 chr11:78285834 NARS2 -0.4 -6.38 -0.33 5.92e-10 Alzheimer's disease (survival time); LIHC cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.21 0.36 3.54e-12 Bipolar disorder; LIHC cis rs9910055 0.529 rs368328 chr17:42170289 G/A cg19774624 chr17:42201019 HDAC5 0.49 5.84 0.3 1.2e-8 Total body bone mineral density; LIHC cis rs1568889 0.838 rs7127069 chr11:28325412 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 14.54 0.62 1.3e-37 Bipolar disorder; LIHC cis rs6815814 0.898 rs5743592 chr4:38803063 A/G cg06935464 chr4:38784597 TLR10 0.46 7.19 0.36 4.18e-12 Breast cancer; LIHC cis rs2243480 1.000 rs1796228 chr7:66033084 G/A cg12463550 chr7:65579703 CRCP 0.67 6.9 0.35 2.49e-11 Diabetic kidney disease; LIHC cis rs61440199 0.818 rs79027229 chr3:20180363 T/C cg00235661 chr3:20228976 SGOL1 -0.42 -5.79 -0.3 1.58e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC trans rs9914544 0.966 rs9915346 chr17:18787931 G/A cg04702396 chr17:15466718 FAM18B2 0.43 6.47 0.33 3.3e-10 Educational attainment (years of education); LIHC cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.69 0.34 9.33e-11 Bipolar disorder; LIHC cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC cis rs10256972 0.616 rs6463001 chr7:1108272 A/C cg07308232 chr7:1071921 C7orf50 -0.46 -7.2 -0.36 3.87e-12 Longevity;Endometriosis; LIHC cis rs9467773 1.000 rs1535277 chr6:26567802 G/T cg09904177 chr6:26538194 HMGN4 0.66 13.75 0.6 1.5e-34 Intelligence (multi-trait analysis); LIHC cis rs1728785 0.818 rs1170430 chr16:68604954 T/C cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs4742903 0.935 rs4743692 chr9:106931890 A/G cg14250997 chr9:106856677 SMC2 0.36 6.05 0.31 3.91e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6502050 0.835 rs8065981 chr17:80091393 G/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC cis rs769267 0.965 rs2315281 chr19:19480099 G/A cg03709012 chr19:19516395 GATAD2A -1.01 -18.1 -0.7 7.56e-52 Tonsillectomy; LIHC cis rs644799 1.000 rs693364 chr11:95621926 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.76 0.3 1.89e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg11890956 chr21:40555474 PSMG1 1.06 15.14 0.63 5.6e-40 Cognitive function; LIHC cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.85 0.3 1.17e-8 Menopause (age at onset); LIHC cis rs986417 0.901 rs12883305 chr14:61006690 A/G cg27398547 chr14:60952738 C14orf39 0.83 9.47 0.46 4.66e-19 Gut microbiota (bacterial taxa); LIHC cis rs11678584 0.502 rs17011982 chr2:32726313 A/G cg02381751 chr2:32503542 YIPF4 0.61 6.06 0.31 3.52e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs10791323 0.572 rs4353292 chr11:133742656 A/G cg06766960 chr11:133703094 NA -0.44 -6.81 -0.35 4.52e-11 Childhood ear infection; LIHC cis rs1494950 1.000 rs16891297 chr4:15034472 A/G cg12377275 chr4:15005593 CPEB2 -0.85 -7.5 -0.38 5.68e-13 Political ideology; LIHC cis rs11190604 0.767 rs10509743 chr10:102190406 C/T cg07080220 chr10:102295463 HIF1AN 0.47 6.87 0.35 2.96e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2235573 0.527 rs5756853 chr22:38329524 G/A cg03989125 chr22:38214979 NA 0.43 5.79 0.3 1.61e-8 Glioblastoma;Glioma; LIHC cis rs7552404 1.000 rs11161511 chr1:76210477 A/G cg03433033 chr1:76189801 ACADM -0.61 -8.77 -0.43 8.53e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6752107 1.000 rs2241880 chr2:234183368 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.54 0.42 4.46e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs12898370 0.641 rs11632999 chr15:77436995 T/G cg17802220 chr15:77601643 NA -0.4 -6.07 -0.31 3.48e-9 Risky sexual behaviors (alcohol dependence interaction); LIHC trans rs12478296 0.786 rs72620862 chr2:243044787 T/C cg01596870 chr19:55963115 NA -0.64 -8.49 -0.42 6.49e-16 Obesity-related traits; LIHC cis rs7847628 0.587 rs4837796 chr9:123610288 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.95 -19.87 -0.73 5.74e-59 Birth weight; LIHC cis rs11662586 0.517 rs11662894 chr18:77713591 G/A cg20368463 chr18:77673604 PQLC1 0.51 8.44 0.42 9.03e-16 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs4268898 0.697 rs6714652 chr2:24383059 C/T cg06627628 chr2:24431161 ITSN2 0.45 6.38 0.33 5.89e-10 Asthma; LIHC cis rs4903214 0.895 rs7161419 chr14:74695757 A/G cg11132536 chr14:74711944 VSX2 -0.25 -6.04 -0.31 3.94e-9 Inflammatory bowel disease; LIHC cis rs9868809 0.505 rs35064573 chr3:48740280 C/A cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.6e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs8180040 0.805 rs17410853 chr3:47363971 G/T cg16586182 chr3:47516702 SCAP 0.5 8.87 0.43 4e-17 Colorectal cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27318635 chr16:3781749 CREBBP 0.41 6.19 0.32 1.71e-9 Longevity; LIHC cis rs7246657 0.943 rs8109038 chr19:38015709 A/G cg23950597 chr19:37808831 NA 0.46 5.72 0.3 2.36e-8 Coronary artery calcification; LIHC trans rs9914544 0.545 rs3803835 chr17:18793061 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.46 -0.33 3.65e-10 Educational attainment (years of education); LIHC cis rs644799 0.542 rs10831417 chr11:95467262 A/G cg03916912 chr11:95522834 CEP57;FAM76B -0.77 -12.05 -0.55 4.28e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1144333 1.000 rs75399471 chr1:76339092 A/T cg03433033 chr1:76189801 ACADM 0.54 7.44 0.37 8.34e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs10431058 0.930 rs7948142 chr11:107478703 T/G cg18204760 chr11:107461044 ELMOD1;LOC643923 0.4 6.48 0.33 3.28e-10 Common traits (Other); LIHC cis rs11676348 0.755 rs13410318 chr2:219022910 T/G cg00012203 chr2:219082015 ARPC2 0.61 8.33 0.41 2.05e-15 Ulcerative colitis; LIHC cis rs2425143 1.000 rs12481228 chr20:34218673 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -5.89 -0.3 9.47e-9 Blood protein levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20518154 chr20:39318705 MAFB 0.47 6.31 0.32 8.54e-10 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16247931 chr14:102771650 RAGE -0.46 -6.16 -0.32 2.09e-9 Pancreatic cancer; LIHC cis rs11098499 0.754 rs7672778 chr4:120248585 A/G cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.14e-25 Corneal astigmatism; LIHC cis rs611744 0.967 rs612265 chr8:109188650 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.37e-17 Dupuytren's disease; LIHC cis rs7927592 0.913 rs7127948 chr11:68363062 G/A cg01657329 chr11:68192670 LRP5 -0.48 -6.21 -0.32 1.54e-9 Total body bone mineral density; LIHC cis rs2228479 0.702 rs11076621 chr16:89837927 A/G cg00800038 chr16:89945340 TCF25 -0.62 -9.31 -0.45 1.63e-18 Skin colour saturation; LIHC cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg03396347 chr1:1875803 NA -0.49 -9.11 -0.44 7.2e-18 Body mass index; LIHC cis rs881375 0.967 rs7034492 chr9:123687211 G/A cg14580859 chr9:123691850 NA 0.39 6.85 0.35 3.45e-11 Rheumatoid arthritis; LIHC cis rs2832191 0.716 rs1888440 chr21:30454484 C/T cg08807101 chr21:30365312 RNF160 0.79 11.9 0.54 1.44e-27 Dental caries; LIHC cis rs2235573 0.551 rs139893 chr22:38393608 G/A cg03989125 chr22:38214979 NA -0.44 -6.16 -0.32 2.06e-9 Glioblastoma;Glioma; LIHC cis rs10752881 1.000 rs6424880 chr1:182986679 C/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs8103278 0.507 rs4802276 chr19:46260748 T/C cg12641515 chr19:46296257 DMWD 0.46 6.94 0.35 2e-11 Coronary artery disease; LIHC cis rs12765878 1.000 rs3850671 chr10:105659387 T/C cg11005552 chr10:105648138 OBFC1 0.38 6.1 0.31 2.85e-9 Coronary artery disease; LIHC cis rs6952808 0.636 rs6964522 chr7:1953523 C/T cg02951883 chr7:2050386 MAD1L1 -0.54 -8.13 -0.4 7.91e-15 Bipolar disorder and schizophrenia; LIHC cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.87 0.35 3.09e-11 Bipolar disorder; LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg00800038 chr16:89945340 TCF25 -0.6 -9.75 -0.47 5.72e-20 Skin colour saturation; LIHC cis rs4919694 0.908 rs11191523 chr10:104792400 A/G cg04362960 chr10:104952993 NT5C2 1.15 9.07 0.44 9.6e-18 Arsenic metabolism; LIHC cis rs1421811 0.606 rs62369523 chr5:32713365 T/G cg16267343 chr5:32710456 NPR3 0.65 6.68 0.34 9.53e-11 Blood pressure; LIHC cis rs507080 0.733 rs4486664 chr11:118569067 A/C cg04173919 chr11:118528438 PHLDB1 0.34 6.27 0.32 1.09e-9 Serum metabolite levels; LIHC cis rs2708977 0.901 rs6753667 chr2:97160382 G/A cg01950434 chr2:97203154 ARID5A -0.5 -7.42 -0.37 9.25e-13 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs4407350 1.000 rs4373013 chr22:44922248 C/T cg11695653 chr22:44894386 LDOC1L -0.37 -6.05 -0.31 3.8e-9 Intelligence (multi-trait analysis); LIHC cis rs9399135 0.967 rs4388304 chr6:135309597 T/A cg24558204 chr6:135376177 HBS1L 0.4 6.62 0.34 1.39e-10 Red blood cell count; LIHC cis rs2239547 0.603 rs34230854 chr3:53078590 C/A cg11645453 chr3:52864694 ITIH4 0.26 6.26 0.32 1.12e-9 Schizophrenia; LIHC cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.64 -10.51 -0.49 1.42e-22 Menarche (age at onset); LIHC cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg14004847 chr7:1930337 MAD1L1 -0.51 -7.57 -0.38 3.46e-13 Schizophrenia; LIHC cis rs4718428 0.705 rs4717331 chr7:66378886 C/T cg12165864 chr7:66369176 NA -0.46 -6.65 -0.34 1.17e-10 Corneal structure; LIHC cis rs3008870 0.755 rs11208974 chr1:67398119 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.77 0.5 1.73e-23 Lymphocyte percentage of white cells; LIHC cis rs9640161 0.659 rs77354576 chr7:150013300 A/C cg10018233 chr7:150070692 REPIN1 0.49 8.35 0.41 1.76e-15 Blood protein levels;Circulating chemerin levels; LIHC trans rs66887589 0.777 rs10015883 chr4:120268146 A/G cg25214090 chr10:38739885 LOC399744 0.4 6.64 0.34 1.25e-10 Diastolic blood pressure; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg21856205 chr7:94953877 PON1 -0.67 -12.44 -0.56 1.46e-29 Paraoxonase activity; LIHC cis rs1008375 0.966 rs1860599 chr4:17638900 T/C cg15017067 chr4:17643749 FAM184B 0.34 5.79 0.3 1.62e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9326778 0.520 rs55796690 chr5:108842398 G/T cg17395555 chr5:108820864 NA -0.37 -6.34 -0.32 7.42e-10 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs332507 0.601 rs3772775 chr3:124369360 C/G cg05980111 chr3:124395277 KALRN -0.31 -5.98 -0.31 5.65e-9 Plateletcrit; LIHC cis rs8072100 0.967 rs62076549 chr17:45579555 T/G cg08085267 chr17:45401833 C17orf57 0.39 5.91 0.3 8.37e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs3008870 1.000 rs2985822 chr1:67404910 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs1003719 0.762 rs11088381 chr21:38478429 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.75 0.54 5.27e-27 Eye color traits; LIHC cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg22963979 chr7:1858916 MAD1L1 -0.38 -6.03 -0.31 4.3e-9 Bipolar disorder and schizophrenia; LIHC cis rs151997 0.925 rs27624 chr5:50167662 C/T cg06027927 chr5:50259733 NA 0.58 7.48 0.37 6.51e-13 Callous-unemotional behaviour; LIHC cis rs2228479 0.850 rs17226666 chr16:89835401 G/A cg19635926 chr16:89946313 TCF25 0.48 6.2 0.32 1.65e-9 Skin colour saturation; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09543727 chr4:120550218 PDE5A 0.45 6.27 0.32 1.07e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1322512 0.883 rs2758814 chr6:152966367 C/T cg03415253 chr6:152958462 SYNE1 -0.33 -6.21 -0.32 1.5e-9 Tonometry; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg22963979 chr7:1858916 MAD1L1 -0.43 -6.82 -0.35 4.15e-11 Bipolar disorder and schizophrenia; LIHC cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg24642844 chr7:1081250 C7orf50 -0.92 -8.96 -0.44 2.13e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9858542 0.953 rs9821311 chr3:49543656 C/T cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4788570 0.616 rs11075901 chr16:71790812 A/C cg06353428 chr16:71660113 MARVELD3 1.36 14.03 0.6 1.21e-35 Intelligence (multi-trait analysis); LIHC cis rs1419980 1.000 rs1419980 chr12:7774892 A/G cg10578777 chr12:7781093 NA -0.48 -7.81 -0.39 7.16e-14 HDL cholesterol levels; LIHC cis rs910316 0.737 rs175072 chr14:75502827 T/C cg11812906 chr14:75593930 NEK9 -0.73 -13.69 -0.59 2.61e-34 Height; LIHC cis rs7208859 0.524 rs11653605 chr17:29088385 T/G cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6750047 0.566 rs1157184 chr2:38285774 C/G cg07380506 chr2:38303506 CYP1B1 0.65 8.43 0.41 9.69e-16 Cutaneous malignant melanoma;Melanoma; LIHC trans rs6489882 0.867 rs6489876 chr12:113368055 G/A cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg20607798 chr8:58055168 NA 0.49 6.11 0.31 2.75e-9 Developmental language disorder (linguistic errors); LIHC cis rs9828933 0.577 rs704374 chr3:63865947 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.84 11.3 0.52 2.29e-25 Type 2 diabetes; LIHC cis rs10463316 0.894 rs7703283 chr5:150764904 C/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.04e-10 Metabolite levels (Pyroglutamine); LIHC cis rs61990749 0.500 rs8011337 chr14:78272626 T/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.53 -0.38 4.45e-13 Fibroblast growth factor basic levels; LIHC cis rs9814567 1.000 rs1917130 chr3:134313773 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.12 0.55 2.31e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6546537 0.562 rs1985342 chr2:69758927 C/T cg10773587 chr2:69614142 GFPT1 -0.5 -6.7 -0.34 8.68e-11 Serum thyroid-stimulating hormone levels; LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.63 10.48 0.49 1.81e-22 Prudent dietary pattern; LIHC cis rs4788570 0.578 rs8062188 chr16:71729825 T/C cg06353428 chr16:71660113 MARVELD3 1.35 13.8 0.6 1e-34 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg12310025 chr6:25882481 NA -0.53 -6.78 -0.34 5.15e-11 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.92 0.57 2.17e-31 Prudent dietary pattern; LIHC cis rs924607 1.000 rs924607 chr5:610093 C/T cg24163568 chr5:669837 TPPP -0.41 -8.6 -0.42 2.98e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs11583043 1.000 rs12750667 chr1:101498682 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.67 0.42 1.71e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7917772 0.636 rs4418737 chr10:104525123 A/G cg22532475 chr10:104410764 TRIM8 0.36 6.34 0.32 7.18e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7188697 0.883 rs4485352 chr16:58601410 A/G cg02549819 chr16:58548995 SETD6 0.48 7.62 0.38 2.52e-13 QT interval; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02408009 chr15:28422194 HERC2 -0.42 -6.33 -0.32 7.67e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg21724239 chr8:58056113 NA 0.59 6.86 0.35 3.17e-11 Developmental language disorder (linguistic errors); LIHC trans rs79976124 0.877 rs79507557 chr6:66640908 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 6.85 0.35 3.54e-11 Type 2 diabetes; LIHC cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg05564831 chr3:52568323 NT5DC2 0.37 6.04 0.31 3.93e-9 Bipolar disorder; LIHC cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6430585 0.527 rs62168830 chr2:136443900 A/T cg07169764 chr2:136633963 MCM6 0.67 8.59 0.42 3.21e-16 Corneal structure; LIHC cis rs919433 0.617 rs700646 chr2:198608511 C/T cg03934865 chr2:198174659 NA 0.48 6.87 0.35 3.09e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg11494091 chr17:61959527 GH2 0.36 6.09 0.31 2.96e-9 Height; LIHC cis rs34779708 0.931 rs34815241 chr10:35296676 T/C cg03585969 chr10:35415529 CREM 0.78 11.75 0.54 5.36e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3812111 0.525 rs3749893 chr6:116571695 A/G cg08036074 chr6:116424633 NT5DC1 -0.44 -7.1 -0.36 7.07e-12 Age-related macular degeneration; LIHC cis rs2991971 0.901 rs11211122 chr1:45954650 C/T cg15605315 chr1:45957053 TESK2 0.47 6.63 0.34 1.29e-10 High light scatter reticulocyte count; LIHC cis rs7818688 0.697 rs74553842 chr8:95984392 C/T cg16049864 chr8:95962084 TP53INP1 0.6 6.55 0.33 2.08e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7395581 1.000 rs830085 chr11:47251199 G/A cg26139080 chr11:47293733 MADD 0.49 8.19 0.4 5.25e-15 HDL cholesterol; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00873521 chr9:95056130 IARS;SNORA84 0.45 6.54 0.33 2.21e-10 Pancreatic cancer; LIHC cis rs9611565 0.506 rs1984839 chr22:41685937 G/C cg06634786 chr22:41940651 POLR3H -0.52 -6.12 -0.31 2.62e-9 Vitiligo; LIHC cis rs8067354 0.540 rs72840315 chr17:58018142 G/C cg02344993 chr17:57696989 CLTC 0.65 10.18 0.48 2.01e-21 Hemoglobin concentration; LIHC cis rs929354 0.742 rs3808317 chr7:156944460 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs5758659 0.714 rs5751216 chr22:42508937 G/T cg19513890 chr22:42538836 CYP2D7P1 0.41 8.29 0.41 2.65e-15 Cognitive function; LIHC cis rs10078 0.571 rs2671890 chr5:456457 A/G cg24955955 chr5:415729 AHRR 0.6 11.17 0.52 6.72e-25 Fat distribution (HIV); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00370926 chr17:7835519 TRAPPC1;CNTROB 0.45 6.27 0.32 1.12e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 0.663 rs10946205 chr6:167451311 A/G cg23791538 chr6:167370224 RNASET2 -0.63 -10.77 -0.5 1.73e-23 Crohn's disease; LIHC cis rs4819052 0.819 rs34818688 chr21:46672416 C/T cg11663144 chr21:46675770 NA -0.33 -6.02 -0.31 4.44e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6545883 0.931 rs778765 chr2:61786385 A/T cg14146966 chr2:61757674 XPO1 0.47 8.11 0.4 9.17e-15 Tuberculosis; LIHC cis rs6456156 0.586 rs9459853 chr6:167465774 C/A cg12798992 chr6:167411361 FGFR1OP 0.5 8.17 0.4 5.95e-15 Primary biliary cholangitis; LIHC cis rs116095464 0.558 rs10462754 chr5:246669 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.68 -0.5 3.47e-23 Breast cancer; LIHC cis rs12477438 0.501 rs6542868 chr2:99782848 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs1559088 0.847 rs2287679 chr19:33600764 T/C cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs921968 0.541 rs6720403 chr2:219294258 A/C cg02176678 chr2:219576539 TTLL4 -0.57 -7.8 -0.39 7.65e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs12579753 0.869 rs12366920 chr12:82223015 G/A cg07988820 chr12:82153109 PPFIA2 -0.48 -5.84 -0.3 1.23e-8 Resting heart rate; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.913 rs11228293 chr11:68384646 T/C cg16797656 chr11:68205561 LRP5 0.49 7.71 0.38 1.39e-13 Total body bone mineral density; LIHC cis rs644799 0.965 rs687529 chr11:95545587 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.82 0.47 3.16e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11098499 0.754 rs1980026 chr4:120251643 C/A cg09307838 chr4:120376055 NA 0.71 11.25 0.52 3.29e-25 Corneal astigmatism; LIHC cis rs7027203 0.828 rs4344139 chr9:96600298 T/C cg14396892 chr9:96623032 NA -0.33 -6.31 -0.32 8.63e-10 DNA methylation (variation); LIHC cis rs3106136 0.872 rs2059605 chr4:95255212 C/T cg11021082 chr4:95130006 SMARCAD1 -0.41 -7.49 -0.38 5.9e-13 Capecitabine sensitivity; LIHC cis rs10197940 0.545 rs2444267 chr2:152308611 T/G cg19508488 chr2:152266495 RIF1 0.48 6.85 0.35 3.41e-11 Lung cancer; LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.87 0.39 4.79e-14 Prudent dietary pattern; LIHC cis rs4423214 1.000 rs4944062 chr11:71187294 G/T cg05163923 chr11:71159392 DHCR7 0.87 12.93 0.57 2.15e-31 Vitamin D levels; LIHC cis rs2732480 0.577 rs2450994 chr12:48721832 G/A cg21466736 chr12:48725269 NA -0.73 -11.46 -0.53 6.2e-26 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs4919087 1.000 rs10882898 chr10:99087330 G/A cg25902810 chr10:99078978 FRAT1 -0.67 -9.94 -0.47 1.29e-20 Monocyte count; LIHC cis rs7727544 0.904 rs6897575 chr5:131604535 C/T cg24060327 chr5:131705240 SLC22A5 -0.52 -5.83 -0.3 1.25e-8 Blood metabolite levels; LIHC cis rs8067545 0.750 rs888423 chr17:19999409 G/A cg13482628 chr17:19912719 NA 0.51 8.24 0.41 3.6e-15 Schizophrenia; LIHC cis rs9733 0.818 rs10888388 chr1:150687296 C/T cg18016565 chr1:150552671 MCL1 -0.5 -10.32 -0.49 6.68e-22 Tonsillectomy; LIHC trans rs2363709 1.000 rs2363713 chr3:67422600 G/A cg25028035 chr6:42016671 CCND3 -0.84 -6.07 -0.31 3.44e-9 IgE levels; LIHC cis rs17001868 0.614 rs5995849 chr22:40777072 C/G cg07138101 chr22:40742427 ADSL -0.49 -5.99 -0.31 5.41e-9 Mammographic density (dense area); LIHC trans rs2018683 1.000 rs4719963 chr7:29011064 A/G cg19402173 chr7:128379420 CALU 0.42 6.86 0.35 3.17e-11 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs11212260 0.573 rs34582397 chr11:107161242 A/G cg25435332 chr11:107328525 CWF19L2 0.65 6.23 0.32 1.38e-9 IgG glycosylation; LIHC cis rs11212260 0.655 rs12225955 chr11:107289846 G/A cg25435332 chr11:107328525 CWF19L2 0.8 8.13 0.4 7.75e-15 IgG glycosylation; LIHC cis rs1198430 0.925 rs7534474 chr1:23773851 A/G cg13183780 chr1:23809682 ASAP3 -0.53 -7.61 -0.38 2.68e-13 Total cholesterol levels; LIHC cis rs138880 0.580 rs28562884 chr22:50312869 T/C cg09182678 chr22:50328711 NA -0.69 -7.62 -0.38 2.47e-13 Schizophrenia; LIHC cis rs72781680 0.898 rs10490752 chr2:24025132 C/T cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs7100689 0.646 rs6585946 chr10:82118292 G/T cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs6988636 1.000 rs57902736 chr8:124189893 G/A cg15893493 chr8:124194847 FAM83A 0.88 8.18 0.4 5.81e-15 Urinary uromodulin levels; LIHC cis rs1568889 1.000 rs11602768 chr11:28351786 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.71 0.34 8.24e-11 Bipolar disorder; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22622886 chr1:9189641 GPR157 0.42 6.05 0.31 3.87e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12744310 0.945 rs72665691 chr1:41775245 T/A cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg06453172 chr10:134556979 INPP5A -0.62 -7.9 -0.39 3.77e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10791097 0.609 rs3751039 chr11:130773076 A/G cg12179176 chr11:130786555 SNX19 -0.9 -16.01 -0.65 1.92e-43 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg13448814 chr8:114447055 CSMD3 -0.42 -6.04 -0.31 4.07e-9 Myopia (pathological); LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.69 -0.34 9.38e-11 Total body bone mineral density; LIHC cis rs951366 0.903 rs823116 chr1:205720483 G/A cg14159672 chr1:205819179 PM20D1 0.32 5.84 0.3 1.19e-8 Menarche (age at onset); LIHC trans rs116095464 0.558 rs9688136 chr5:229348 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs12701220 0.655 rs7799656 chr7:1140515 C/T cg00990874 chr7:1149470 C7orf50 -0.68 -9.79 -0.47 4e-20 Bronchopulmonary dysplasia; LIHC cis rs7523273 0.565 rs2796232 chr1:207900368 T/A cg22525895 chr1:207977042 MIR29B2 -0.53 -8.18 -0.4 5.47e-15 Schizophrenia; LIHC cis rs2576037 0.583 rs487386 chr18:44377004 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.78 -0.3 1.64e-8 Personality dimensions; LIHC cis rs763014 0.932 rs35067229 chr16:649638 T/C cg00908189 chr16:619842 PIGQ 0.83 13.97 0.6 2.14e-35 Height; LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg18306943 chr3:40428807 ENTPD3 0.43 7.58 0.38 3.19e-13 Renal cell carcinoma; LIHC cis rs932287 0.540 rs4910442 chr11:9044337 T/C cg12365402 chr11:9010492 NRIP3 0.29 7.38 0.37 1.2e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg10217327 chr6:118973057 C6orf204 0.7 7.26 0.37 2.67e-12 Diastolic blood pressure; LIHC cis rs1982963 0.951 rs56834750 chr14:52509483 T/C cg10843707 chr14:52510701 NID2 -0.47 -8.59 -0.42 3.21e-16 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7412746 0.658 rs6677420 chr1:150946490 G/A cg15448220 chr1:150897856 SETDB1 0.44 6.91 0.35 2.35e-11 Melanoma; LIHC cis rs7659604 0.540 rs10007956 chr4:122700669 A/T cg19671926 chr4:122722719 EXOSC9 0.52 8.0 0.4 1.95e-14 Type 2 diabetes; LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 10.48 0.49 1.73e-22 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs2370759 1.000 rs11008865 chr10:32574842 C/T cg01819863 chr10:32635814 EPC1 1.11 16.42 0.66 4.34e-45 Sexual dysfunction (female); LIHC cis rs34779708 0.966 rs11010102 chr10:35411066 T/A cg03585969 chr10:35415529 CREM 0.87 13.18 0.58 2.31e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6728642 0.908 rs10203833 chr2:98017363 G/A cg26665480 chr2:98280029 ACTR1B -0.61 -6.82 -0.35 4.12e-11 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs3781458 0.842 rs897300 chr10:126320902 A/G cg20435097 chr10:126320824 FAM53B 0.72 14.32 0.61 9.36e-37 Male-pattern baldness; LIHC cis rs7100689 0.697 rs4934084 chr10:82116960 T/C cg01528321 chr10:82214614 TSPAN14 0.87 11.84 0.54 2.43e-27 Post bronchodilator FEV1; LIHC cis rs881375 0.678 rs10118357 chr9:123680068 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.68 0.34 9.44e-11 Rheumatoid arthritis; LIHC cis rs11098499 0.722 rs17595727 chr4:120262074 C/T cg09307838 chr4:120376055 NA -0.61 -9.25 -0.45 2.54e-18 Corneal astigmatism; LIHC cis rs12824058 0.707 rs2398509 chr12:130816464 T/C cg24838063 chr12:130822603 PIWIL1 0.66 9.47 0.46 4.81e-19 Menopause (age at onset); LIHC cis rs2842992 0.789 rs2146163 chr6:160224346 T/C cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.63 0.56 2.93e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs12744310 0.887 rs34152153 chr1:41801408 T/C cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs35110281 0.805 rs8131005 chr21:45041954 T/C cg04455712 chr21:45112962 RRP1B 0.42 7.52 0.38 4.84e-13 Mean corpuscular volume; LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg14671364 chr1:107599128 PRMT6 -0.5 -7.37 -0.37 1.27e-12 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg05947499 chr12:113704091 TPCN1 0.42 6.49 0.33 3e-10 Bilirubin levels; LIHC cis rs6748734 1.000 rs4344931 chr2:241818527 A/C cg08694578 chr2:241835147 C2orf54 -0.48 -6.62 -0.34 1.39e-10 Urinary metabolites; LIHC cis rs950169 0.959 rs12902070 chr15:84793558 T/C cg03959625 chr15:84868606 LOC388152 0.49 6.15 0.32 2.12e-9 Schizophrenia; LIHC cis rs8062405 0.679 rs72793818 chr16:28893137 G/A cg07451762 chr16:28383216 NA 0.32 5.98 0.31 5.58e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3749237 0.595 rs1568661 chr3:49520958 A/G cg02487422 chr3:49467188 NICN1 0.4 6.3 0.32 9.04e-10 Resting heart rate; LIHC trans rs10506458 0.915 rs1009540 chr12:63414872 C/A cg22491629 chr6:157744540 C6orf35 -0.6 -10.83 -0.51 1.09e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg03452623 chr4:187889614 NA -0.33 -8.51 -0.42 5.73e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs912330 0.825 rs7317938 chr13:99234361 C/T cg07423050 chr13:99094983 FARP1 -0.37 -6.38 -0.33 5.85e-10 Alzheimer's disease; LIHC cis rs4919087 0.651 rs12240590 chr10:99072066 C/G cg25902810 chr10:99078978 FRAT1 -0.6 -7.23 -0.36 3.16e-12 Monocyte count; LIHC cis rs10864907 0.614 rs7557537 chr2:113702530 T/C cg12858261 chr2:113808755 IL1F8 0.34 5.94 0.31 7.18e-9 Pulmonary function; LIHC cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg16049864 chr8:95962084 TP53INP1 -0.64 -12.04 -0.55 4.63e-28 Type 2 diabetes; LIHC cis rs2274273 1.000 rs4644 chr14:55604935 C/A cg01864836 chr14:55583639 NA -0.36 -6.15 -0.32 2.14e-9 Protein biomarker; LIHC trans rs61931739 0.500 rs11053197 chr12:34441949 C/T cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs67460515 0.892 rs73026976 chr3:160964271 G/A cg17135325 chr3:160939158 NMD3 0.55 7.84 0.39 5.59e-14 Parkinson's disease; LIHC cis rs3740540 0.530 rs10794163 chr10:126291398 A/G cg04949429 chr10:126290192 LHPP 0.44 7.2 0.36 3.97e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs2562152 0.706 rs216596 chr16:105320 A/G cg02949481 chr16:131562 MPG 0.43 6.64 0.34 1.2e-10 Glioblastoma; LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg09535738 chr8:17500436 PDGFRL 0.51 6.07 0.31 3.42e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs116095464 0.558 rs7703803 chr5:292311 A/G cg22496380 chr5:211416 CCDC127 -1.0 -10.32 -0.49 6.61e-22 Breast cancer; LIHC cis rs67981189 0.593 rs10140225 chr14:71491121 T/C cg15816911 chr14:71606274 NA 0.4 6.4 0.33 5.1e-10 Schizophrenia; LIHC cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg16434002 chr17:42200994 HDAC5 -0.53 -7.58 -0.38 3.29e-13 Total body bone mineral density; LIHC trans rs9929218 0.953 rs12930910 chr16:68762520 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.47 -0.46 4.59e-19 Colorectal cancer; LIHC trans rs13113518 0.812 rs12501746 chr4:56303605 C/T cg15358633 chr12:38710606 ALG10B 0.44 6.29 0.32 9.6e-10 Height; LIHC cis rs4845459 0.967 rs4845450 chr1:152591200 T/C cg20634798 chr1:152595351 LCE3A -0.32 -6.2 -0.32 1.63e-9 Psoriasis; LIHC cis rs763121 0.889 rs4820335 chr22:38935927 C/G cg06022373 chr22:39101656 GTPBP1 -0.59 -10.89 -0.51 6.77e-24 Menopause (age at onset); LIHC cis rs7927592 0.546 rs638076 chr11:68202580 A/G cg16797656 chr11:68205561 LRP5 0.6 11.04 0.51 1.89e-24 Total body bone mineral density; LIHC cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.51 0.56 7.88e-30 Alzheimer's disease; LIHC cis rs7707921 0.767 rs862242 chr5:81587566 C/T cg15871215 chr5:81402204 ATG10 -0.68 -8.21 -0.41 4.7e-15 Breast cancer; LIHC cis rs12594515 1.000 rs8029209 chr15:45993489 A/G cg06207120 chr15:45996521 NA 0.32 6.02 0.31 4.55e-9 Waist circumference;Weight; LIHC cis rs6449957 0.801 rs921792 chr5:67465803 C/T cg23036683 chr5:67512108 NA 0.45 6.57 0.33 1.85e-10 Cleft lip with or without cleft palate; LIHC cis rs2281845 0.859 rs4915216 chr1:201077469 T/G cg24849736 chr1:201084428 NA -0.33 -5.77 -0.3 1.73e-8 Permanent tooth development; LIHC cis rs1538970 0.884 rs61788261 chr1:45899114 G/A cg15605315 chr1:45957053 TESK2 -0.44 -5.71 -0.3 2.43e-8 Platelet count; LIHC cis rs921968 0.643 rs6708683 chr2:219504503 G/A cg02985541 chr2:219472218 PLCD4 0.41 7.38 0.37 1.2e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs4742903 0.935 rs10991165 chr9:106973498 A/G cg14250997 chr9:106856677 SMC2 -0.35 -5.87 -0.3 1.05e-8 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg21747090 chr2:27597821 SNX17 -0.44 -6.5 -0.33 2.85e-10 Total body bone mineral density; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC trans rs9531686 0.935 rs4635230 chr13:85546607 A/C cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.3 0.32 9.31e-10 Anorexia nervosa; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg17512779 chr8:17104072 CNOT7;VPS37A -0.44 -6.21 -0.32 1.52e-9 Monocyte count; LIHC trans rs11098499 0.779 rs6815934 chr4:120267310 T/C cg25214090 chr10:38739885 LOC399744 0.43 7.09 0.36 7.52e-12 Corneal astigmatism; LIHC trans rs66887589 0.934 rs6817317 chr4:120542827 A/G cg25214090 chr10:38739885 LOC399744 -0.39 -6.24 -0.32 1.27e-9 Diastolic blood pressure; LIHC cis rs6840360 0.615 rs4696094 chr4:152465501 C/T cg22705602 chr4:152727874 NA -0.32 -6.31 -0.32 8.61e-10 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.57 0.46 2.25e-19 Height; LIHC cis rs8180040 0.932 rs11712445 chr3:47434552 T/C cg27129171 chr3:47204927 SETD2 0.56 9.46 0.46 5.02e-19 Colorectal cancer; LIHC cis rs599083 0.530 rs640569 chr11:68184820 A/G cg16797656 chr11:68205561 LRP5 -0.49 -7.64 -0.38 2.18e-13 Bone mineral density (spine); LIHC cis rs8062405 0.723 rs35175818 chr16:28608746 A/C cg16576597 chr16:28551801 NUPR1 0.48 7.31 0.37 1.95e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs733592 0.507 rs7299704 chr12:48444488 A/G cg21466736 chr12:48725269 NA -0.34 -5.96 -0.31 6.2e-9 Plateletcrit; LIHC cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg11062466 chr8:58055876 NA 0.39 5.74 0.3 2.05e-8 Developmental language disorder (linguistic errors); LIHC cis rs7100689 0.646 rs1572819 chr10:82112488 A/G cg00277334 chr10:82204260 NA -0.56 -6.94 -0.35 2.02e-11 Post bronchodilator FEV1; LIHC cis rs6504950 0.800 rs72829484 chr17:53009280 G/T cg10237252 chr17:52977213 TOM1L1 -0.35 -6.15 -0.32 2.15e-9 Breast cancer; LIHC cis rs1336900 0.641 rs6587756 chr1:150546865 A/T cg18016565 chr1:150552671 MCL1 -0.68 -13.38 -0.59 4.07e-33 Blood protein levels; LIHC cis rs10752881 1.000 rs4402094 chr1:182986441 G/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs17685 0.753 rs6953665 chr7:75769049 C/T cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6867032 0.958 rs4246754 chr5:2014776 A/C cg26168224 chr5:2018326 NA 0.33 8.46 0.42 7.96e-16 Gut microbiome composition (winter); LIHC cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg26116260 chr4:7069785 GRPEL1 -0.91 -16.18 -0.66 3.92e-44 Monocyte percentage of white cells; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.85 -0.3 1.16e-8 Total body bone mineral density; LIHC trans rs11098499 0.820 rs6534140 chr4:120455311 C/T cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg16060761 chr17:80687452 NA -0.46 -6.93 -0.35 2.13e-11 Glycated hemoglobin levels; LIHC trans rs2073499 1.000 rs2073498 chr3:50369546 C/A cg21659725 chr3:3221576 CRBN 0.62 6.04 0.31 3.98e-9 Schizophrenia; LIHC trans rs1814175 0.588 rs7481648 chr11:49754910 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.81 0.35 4.37e-11 Height; LIHC cis rs1401999 0.966 rs2037379 chr3:183650330 T/C cg05044414 chr3:183734942 ABCC5 0.33 5.81 0.3 1.43e-8 Anterior chamber depth; LIHC cis rs7607369 0.580 rs7594289 chr2:219652286 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -5.89 -0.3 9.26e-9 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs55823223 0.564 rs1463485 chr17:73851791 C/G cg08125733 chr17:73851984 WBP2 0.86 12.48 0.56 1.07e-29 Psoriasis; LIHC cis rs4561483 0.801 rs251723 chr16:11953080 G/C cg08843971 chr16:11963173 GSPT1 -0.42 -8.39 -0.41 1.29e-15 Testicular germ cell tumor; LIHC cis rs5769765 0.862 rs9616384 chr22:50313082 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs6809651 0.524 rs7622914 chr3:185790895 T/C cg00760338 chr3:185826511 ETV5 -0.79 -11.84 -0.54 2.52e-27 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC trans rs561341 0.825 rs2008368 chr17:30347397 T/C cg20587970 chr11:113659929 NA -1.36 -11.75 -0.54 5.3e-27 Hip circumference adjusted for BMI; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06240896 chr7:100136768 AGFG2 0.47 6.5 0.33 2.84e-10 Lung function (FEV1/FVC); LIHC cis rs9814567 0.964 rs1534028 chr3:134284639 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7615952 0.611 rs2971298 chr3:125602713 G/A cg05084668 chr3:125655381 ALG1L -0.76 -10.41 -0.49 3.22e-22 Blood pressure (smoking interaction); LIHC cis rs1046896 0.586 rs9897951 chr17:80810662 T/C cg19500275 chr17:80737654 TBCD 0.4 5.77 0.3 1.77e-8 Glycated hemoglobin levels; LIHC cis rs4700695 1.000 rs111339 chr5:65420347 T/A cg21114390 chr5:65439923 SFRS12 -0.52 -7.03 -0.36 1.14e-11 Facial morphology (factor 19); LIHC cis rs1707322 0.686 rs3014235 chr1:46091512 A/G cg24296786 chr1:45957014 TESK2 0.41 5.94 0.31 7.15e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7674212 0.541 rs2615539 chr4:104081106 C/G cg16532752 chr4:104119610 CENPE -0.46 -7.39 -0.37 1.11e-12 Type 2 diabetes; LIHC cis rs2115630 0.641 rs11073613 chr15:85185893 G/A cg11189052 chr15:85197271 WDR73 -0.45 -6.66 -0.34 1.06e-10 P wave terminal force; LIHC cis rs2463822 1.000 rs2246920 chr11:62104937 T/G cg06239285 chr11:62104954 ASRGL1 0.87 6.74 0.34 6.93e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs72627123 0.867 rs57482759 chr14:74485523 G/A cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 6.02 0.31 4.59e-9 Morning vs. evening chronotype; LIHC cis rs8084351 0.539 rs9947827 chr18:50622997 G/A cg24270629 chr18:50823537 DCC 0.43 6.48 0.33 3.2e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs4843747 0.749 rs13333619 chr16:88072076 C/T cg06050784 chr16:88016603 BANP 0.45 8.01 0.4 1.76e-14 Menopause (age at onset); LIHC cis rs736408 0.812 rs9324 chr3:52825585 T/C cg11645453 chr3:52864694 ITIH4 0.22 5.85 0.3 1.14e-8 Bipolar disorder; LIHC trans rs7618501 0.633 rs2624843 chr3:49997963 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.55 9.05 0.44 1.1e-17 Intelligence (multi-trait analysis); LIHC cis rs992157 0.560 rs12992937 chr2:219087072 A/T cg00012203 chr2:219082015 ARPC2 -0.88 -15.33 -0.64 9.23e-41 Colorectal cancer; LIHC cis rs6977660 1.000 rs6955510 chr7:19821333 G/C cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03263168 chr2:158732716 ACVR1 0.46 6.54 0.33 2.2e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9430161 0.611 rs2095920 chr1:11033457 T/A cg02454025 chr1:11042201 C1orf127 0.96 18.34 0.7 8.49e-53 Ewing sarcoma; LIHC cis rs77106637 1.000 rs11600585 chr11:72727840 A/G cg03713592 chr11:72463424 ARAP1 0.79 6.96 0.35 1.77e-11 Type 2 diabetes; LIHC cis rs3741404 0.574 rs616563 chr11:63877501 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.7 11.06 0.51 1.69e-24 Platelet count; LIHC cis rs9916302 0.861 rs3889368 chr17:37683231 C/T cg15445000 chr17:37608096 MED1 0.38 5.8 0.3 1.54e-8 Glomerular filtration rate (creatinine); LIHC cis rs17401966 1.000 rs11576866 chr1:10414432 A/G cg19773385 chr1:10388646 KIF1B -0.46 -7.66 -0.38 1.9e-13 Hepatocellular carcinoma; LIHC cis rs1355223 0.583 rs2941058 chr11:34880245 C/G cg24088639 chr11:34937564 PDHX;APIP -0.39 -6.25 -0.32 1.26e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs67311347 1.000 rs12638199 chr3:40475285 A/G cg09455208 chr3:40491958 NA 0.34 7.02 0.35 1.21e-11 Renal cell carcinoma; LIHC cis rs2204008 0.550 rs11495600 chr12:38126654 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs4474465 1.000 rs7934678 chr11:78192968 G/A cg27205649 chr11:78285834 NARS2 -0.37 -5.79 -0.3 1.63e-8 Alzheimer's disease (survival time); LIHC cis rs6964587 0.839 rs6949700 chr7:91467435 A/G cg17063962 chr7:91808500 NA 0.93 17.08 0.68 9.97e-48 Breast cancer; LIHC cis rs1801251 0.727 rs283482 chr2:233646920 A/T cg25237894 chr2:233734115 C2orf82 0.44 8.51 0.42 5.6e-16 Coronary artery disease; LIHC cis rs992157 0.798 rs1017698 chr2:219170525 A/G cg00012203 chr2:219082015 ARPC2 -0.82 -13.45 -0.59 2.22e-33 Colorectal cancer; LIHC cis rs763121 0.853 rs5757226 chr22:39070550 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg23758822 chr17:41437982 NA 0.93 17.45 0.69 3.28e-49 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06874399 chr5:79704109 ZFYVE16 0.45 6.09 0.31 3.06e-9 Lung function (FEV1/FVC); LIHC cis rs3814231 0.531 rs17090904 chr10:115476138 C/T cg24846397 chr10:115438155 CASP7 -0.41 -6.83 -0.35 3.83e-11 Vitiligo; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg11494091 chr17:61959527 GH2 0.44 7.9 0.39 3.86e-14 Prudent dietary pattern; LIHC cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs3008870 1.000 rs6673462 chr1:67461857 A/C cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs17253792 0.598 rs12880362 chr14:56017929 G/C cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs9583531 1.000 rs9583531 chr13:111385161 T/G cg24331049 chr13:111365604 ING1 -0.66 -8.87 -0.43 3.99e-17 Coronary artery disease; LIHC cis rs9324022 0.858 rs1004573 chr14:101178235 G/C cg18089426 chr14:101175970 NA 0.48 6.02 0.31 4.48e-9 Plateletcrit; LIHC cis rs6546550 0.901 rs11893500 chr2:70154187 T/C cg02498382 chr2:70120550 SNRNP27 -0.44 -7.63 -0.38 2.31e-13 Prevalent atrial fibrillation; LIHC trans rs7618501 0.902 rs7645061 chr3:49868842 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.8 14.65 0.62 4.81e-38 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.740 rs10946204 chr6:167451129 T/C cg12798992 chr6:167411361 FGFR1OP 0.49 7.27 0.37 2.49e-12 Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11769966 chr7:140396384 LOC100134713;NDUFB2 0.45 6.16 0.32 2.02e-9 Lung function (FEV1/FVC); LIHC cis rs7208859 0.623 rs8079891 chr17:29058863 G/A cg14067834 chr17:29058358 SUZ12P 0.68 6.79 0.34 5.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12980942 0.810 rs35812313 chr19:41789178 T/C cg25627403 chr19:41769009 HNRNPUL1 0.58 7.06 0.36 9.13e-12 Coronary artery disease; LIHC cis rs1401999 1.000 rs869417 chr3:183689138 T/C cg01324343 chr3:183735012 ABCC5 0.78 12.88 0.57 3.2e-31 Anterior chamber depth; LIHC cis rs9457247 1.000 rs415842 chr6:167406681 G/A cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.51 1.09e-24 Crohn's disease; LIHC cis rs875971 0.862 rs9791713 chr7:66105198 C/A cg18876405 chr7:65276391 NA -0.34 -6.17 -0.32 1.97e-9 Aortic root size; LIHC cis rs1878931 0.697 rs10048148 chr16:3417450 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.86 15.36 0.64 7.3400000000000005e-41 Body mass index (adult); LIHC cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.51 0.33 2.68e-10 Bipolar disorder; LIHC cis rs908922 0.628 rs488393 chr1:152489548 C/T cg20991723 chr1:152506922 NA 0.47 8.23 0.41 3.94e-15 Hair morphology; LIHC cis rs3917254 0.509 rs13035227 chr2:102763837 T/C cg22835712 chr2:102737379 NA -0.5 -5.75 -0.3 1.94e-8 Blood protein levels; LIHC cis rs208520 0.739 rs1935894 chr6:66891434 A/G cg07460842 chr6:66804631 NA -0.76 -8.55 -0.42 4.3e-16 Exhaled nitric oxide output; LIHC cis rs13108904 0.901 rs66987549 chr4:1272617 C/T cg19318889 chr4:1322082 MAEA 0.52 8.57 0.42 3.62e-16 Obesity-related traits; LIHC cis rs9420 0.528 rs7102271 chr11:57396825 G/T cg19752551 chr11:57585705 CTNND1 -0.45 -5.81 -0.3 1.4e-8 Schizophrenia; LIHC cis rs950169 0.920 rs11637666 chr15:84703874 A/G cg17507749 chr15:85114479 UBE2QP1 0.7 6.67 0.34 1.01e-10 Schizophrenia; LIHC trans rs75804782 0.521 rs60779166 chr2:239433943 G/A cg01134436 chr17:81009848 B3GNTL1 0.75 6.36 0.33 6.41e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg06634786 chr22:41940651 POLR3H -0.81 -8.24 -0.41 3.82e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs933688 1.000 rs10059163 chr5:90742444 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.82 0.69 1.01e-50 Smoking behavior; LIHC cis rs7296418 0.636 rs11057261 chr12:123797567 T/C cg00376283 chr12:123451042 ABCB9 0.62 10.31 0.49 6.98e-22 Platelet count; LIHC cis rs11031096 0.782 rs4910889 chr11:4153231 T/C cg18678763 chr11:4115507 RRM1 -0.53 -8.08 -0.4 1.14e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7103648 1.000 rs7103648 chr11:47461783 A/G cg20307385 chr11:47447363 PSMC3 1.04 18.81 0.71 1.09e-54 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs8141529 0.509 rs5762853 chr22:29245231 T/G cg15103426 chr22:29168792 CCDC117 0.65 10.42 0.49 2.84e-22 Lymphocyte counts; LIHC cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg11764359 chr7:65958608 NA 0.65 6.35 0.32 6.86e-10 Diabetic kidney disease; LIHC cis rs12497850 0.897 rs6446252 chr3:48911125 C/T cg06212747 chr3:49208901 KLHDC8B 0.56 7.17 0.36 4.76e-12 Parkinson's disease; LIHC cis rs4742903 0.935 rs10820616 chr9:106945991 G/A cg14250997 chr9:106856677 SMC2 0.36 5.94 0.31 7.02e-9 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs11039798 0.588 rs113800184 chr11:48756855 G/A cg15704280 chr7:45808275 SEPT13 0.61 6.98 0.35 1.51e-11 Axial length; LIHC cis rs13161895 0.646 rs75894617 chr5:179499854 G/C cg06664874 chr5:179499304 RNF130 0.69 7.35 0.37 1.47e-12 LDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04865659 chr15:90771840 SEMA4B -0.45 -6.16 -0.32 2.06e-9 Lung function (FEV1/FVC); LIHC cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg10360323 chr17:41437877 NA 0.4 5.98 0.31 5.76e-9 Menopause (age at onset); LIHC cis rs7780883 0.821 rs7789836 chr7:77060365 A/T cg12876866 chr7:77025528 PION -0.48 -5.82 -0.3 1.38e-8 Cervical cancer; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg23131131 chr22:24373011 LOC391322 -0.65 -9.71 -0.46 7.46e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs67311347 0.824 rs59922539 chr3:40337110 G/A cg18306943 chr3:40428807 ENTPD3 0.35 5.86 0.3 1.07e-8 Renal cell carcinoma; LIHC cis rs1865760 1.000 rs9467636 chr6:25919549 A/C cg03517284 chr6:25882590 NA -0.38 -5.76 -0.3 1.83e-8 Height; LIHC cis rs801193 1.000 rs7785213 chr7:66138978 A/C cg00343986 chr7:65444356 GUSB -0.4 -5.98 -0.31 5.5e-9 Aortic root size; LIHC cis rs1580019 0.922 rs1466147 chr7:32486262 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.94 15.71 0.65 2.93e-42 Cognitive ability; LIHC cis rs6960043 1.000 rs12113083 chr7:15051943 G/C cg19272540 chr7:15055459 NA -0.23 -6.44 -0.33 4.03e-10 Type 2 diabetes; LIHC trans rs1493916 0.837 rs10401087 chr18:31320716 A/G cg27147174 chr7:100797783 AP1S1 -0.48 -7.12 -0.36 6.42e-12 Life satisfaction; LIHC cis rs7192750 0.562 rs9889011 chr16:71987816 T/A cg06353428 chr16:71660113 MARVELD3 0.77 8.89 0.43 3.46e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs651907 0.557 rs12629954 chr3:101360623 C/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.15 0.52 7.79e-25 Colorectal cancer; LIHC cis rs2115630 0.818 rs7176522 chr15:85215383 C/G cg11189052 chr15:85197271 WDR73 -0.4 -5.96 -0.31 6.45e-9 P wave terminal force; LIHC cis rs4631830 0.720 rs2611475 chr10:51503178 G/A cg20129853 chr10:51489980 NA -0.39 -8.51 -0.42 5.5e-16 Prostate-specific antigen levels; LIHC cis rs9911578 1.000 rs4372750 chr17:57013803 A/C cg05425664 chr17:57184151 TRIM37 0.6 8.85 0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg13271783 chr10:134563150 INPP5A -0.6 -7.18 -0.36 4.32e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs11098499 0.863 rs11098531 chr4:120465001 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.52 0.46 3.25e-19 Corneal astigmatism; LIHC cis rs1348850 0.608 rs10176632 chr2:178225934 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.8 12.17 0.55 1.45e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7937890 0.559 rs10766184 chr11:14542577 A/G cg02886208 chr11:14281011 SPON1 -0.44 -6.18 -0.32 1.82e-9 Mitochondrial DNA levels; LIHC cis rs1559088 0.546 rs11881543 chr19:33559372 T/G cg17764715 chr19:33622953 WDR88 0.53 7.06 0.36 9.43e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs929354 0.742 rs2107863 chr7:156963731 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs11628318 0.614 rs8010455 chr14:103164681 A/G cg12046867 chr14:103022105 NA 0.53 7.53 0.38 4.54e-13 Platelet count; LIHC trans rs2096176 0.530 rs36024300 chr10:26303585 G/T cg01396774 chr2:218299024 DIRC3 -0.31 -6.2 -0.32 1.58e-9 Obesity-related traits; LIHC cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg24209194 chr3:40518798 ZNF619 0.52 7.72 0.39 1.33e-13 Renal cell carcinoma; LIHC cis rs7666738 0.962 rs2865991 chr4:99067369 C/A cg05340658 chr4:99064831 C4orf37 0.69 11.69 0.53 8.71e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7216064 0.953 rs58141639 chr17:65864902 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs1005277 0.579 rs2103938 chr10:38493998 T/G cg25427524 chr10:38739819 LOC399744 -0.75 -15.08 -0.63 9.48e-40 Extrinsic epigenetic age acceleration; LIHC cis rs6762 0.719 rs1130698 chr11:838542 C/T cg07691484 chr11:842764 TSPAN4;POLR2L -0.7 -8.61 -0.42 2.69e-16 Mean platelet volume; LIHC cis rs9527 0.525 rs12770034 chr10:104635595 A/G cg15744005 chr10:104629667 AS3MT -0.42 -9.56 -0.46 2.48e-19 Arsenic metabolism; LIHC cis rs523522 0.962 rs11065154 chr12:120971417 T/C cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs2404602 0.552 rs11636612 chr15:76959530 C/T cg23625390 chr15:77176239 SCAPER -0.45 -6.97 -0.35 1.61e-11 Blood metabolite levels; LIHC cis rs950169 0.723 rs17589320 chr15:84919996 C/A cg12863693 chr15:85201151 NMB 0.41 5.83 0.3 1.31e-8 Schizophrenia; LIHC cis rs6963495 0.818 rs117907809 chr7:105168472 C/A cg19920283 chr7:105172520 RINT1 0.69 6.42 0.33 4.54e-10 Bipolar disorder (body mass index interaction); LIHC cis rs12497850 0.931 rs6446205 chr3:49035211 C/T cg06212747 chr3:49208901 KLHDC8B 0.57 7.3 0.37 2e-12 Parkinson's disease; LIHC cis rs68170813 0.559 rs7798223 chr7:106829223 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs1552244 0.688 rs7645137 chr3:10020549 A/AT cg18598329 chr3:10140678 FANCD2;C3orf24 -0.64 -9.43 -0.45 6.24e-19 Alzheimer's disease; LIHC cis rs7914558 1.000 rs4917380 chr10:104775335 C/G cg15744005 chr10:104629667 AS3MT -0.39 -8.75 -0.43 1.02e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs61931739 0.500 rs7965679 chr12:34542494 T/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs3812111 0.706 rs4946140 chr6:116477278 C/T cg08036074 chr6:116424633 NT5DC1 -0.49 -8.33 -0.41 1.94e-15 Age-related macular degeneration; LIHC cis rs7107174 1.000 rs11602622 chr11:78010830 A/G cg02023728 chr11:77925099 USP35 0.49 9.33 0.45 1.35e-18 Testicular germ cell tumor; LIHC cis rs2197308 0.765 rs11182964 chr12:37935052 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs208520 0.802 rs4710315 chr6:66887594 A/G cg07460842 chr6:66804631 NA -0.76 -8.33 -0.41 2.05e-15 Exhaled nitric oxide output; LIHC cis rs3806843 0.966 rs1030163 chr5:140185132 G/A cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2235573 0.527 rs139878 chr22:38361559 C/T cg03989125 chr22:38214979 NA -0.44 -6.08 -0.31 3.23e-9 Glioblastoma;Glioma; LIHC cis rs9914988 0.887 rs4795463 chr17:27146389 G/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs2742540 0.505 rs2742493 chr11:8967592 A/C cg00186954 chr11:8933980 ST5;C11orf17 0.36 5.83 0.3 1.3e-8 Hematocrit; LIHC cis rs2839627 0.561 rs8126478 chr21:44318668 C/A cg18192155 chr21:44258298 NA 0.44 6.22 0.32 1.42e-9 Information processing speed; LIHC cis rs1403694 1.000 rs1656911 chr3:186439373 T/C cg12454167 chr3:186435060 KNG1 0.29 7.09 0.36 7.92e-12 Blood protein levels; LIHC cis rs1555322 0.530 rs6060347 chr20:33874151 A/G cg17927777 chr20:33865990 NA 0.52 6.27 0.32 1.08e-9 Attention deficit hyperactivity disorder; LIHC cis rs17270561 0.583 rs6908713 chr6:25703611 G/A cg17691542 chr6:26056736 HIST1H1C -0.44 -5.94 -0.31 7.1e-9 Iron status biomarkers; LIHC cis rs3762637 1.000 rs72960431 chr3:122228661 T/C cg24169773 chr3:122142474 KPNA1 -0.45 -8.96 -0.44 2.12e-17 LDL cholesterol levels; LIHC cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.37 -0.56 2.56e-29 Alzheimer's disease; LIHC trans rs9929218 0.551 rs2274239 chr16:68725783 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.91 20.87 0.75 5.76e-63 Colorectal cancer; LIHC cis rs10779751 1.000 rs12124983 chr1:11286178 C/T cg08854313 chr1:11322531 MTOR -0.82 -15.1 -0.63 7.57e-40 Body mass index; LIHC cis rs1577917 0.771 rs2783171 chr6:86382765 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.47 8.14 0.4 7.46e-15 Response to antipsychotic treatment; LIHC cis rs68170813 0.559 rs75154004 chr7:106903326 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs12701220 0.894 rs13224488 chr7:1052353 C/A cg26769984 chr7:1090371 C7orf50 0.59 7.48 0.38 6.22e-13 Bronchopulmonary dysplasia; LIHC cis rs6752107 1.000 rs35300242 chr2:234168790 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.35 0.41 1.75e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1552244 0.572 rs3894322 chr3:10168965 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC cis rs9503598 0.502 rs17309827 chr6:3433318 A/C cg00476032 chr6:3446245 SLC22A23 -0.32 -5.82 -0.3 1.34e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.04 -0.48 5.96e-21 Platelet count; LIHC cis rs67311347 0.577 rs11712626 chr3:40259927 G/A cg10755058 chr3:40428713 ENTPD3 0.35 5.75 0.3 1.95e-8 Renal cell carcinoma; LIHC cis rs2070488 0.965 rs2300668 chr3:38540541 A/G cg24069376 chr3:38537580 EXOG -0.42 -7.72 -0.39 1.3e-13 Electrocardiographic conduction measures; LIHC cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg04025307 chr7:1156635 C7orf50 0.54 8.92 0.43 2.9e-17 Longevity;Endometriosis; LIHC cis rs5769765 0.671 rs138832 chr22:50178082 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.54 -6.7 -0.34 8.78e-11 Schizophrenia; LIHC cis rs7937682 0.855 rs539553 chr11:111477333 C/T cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.63e-24 Primary sclerosing cholangitis; LIHC cis rs7587476 0.784 rs13032278 chr2:215698034 G/A cg04530015 chr2:215796436 ABCA12 -0.39 -6.39 -0.33 5.58e-10 Neuroblastoma; LIHC cis rs561341 1.000 rs546748 chr17:30324293 A/C cg13647721 chr17:30228624 UTP6 0.69 6.72 0.34 7.39e-11 Hip circumference adjusted for BMI; LIHC cis rs6840360 1.000 rs1896883 chr4:152595373 C/T cg22705602 chr4:152727874 NA 0.31 6.53 0.33 2.35e-10 Intelligence (multi-trait analysis); LIHC trans rs783540 0.900 rs783525 chr15:83284629 T/A cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.18 -0.32 1.87e-9 Schizophrenia; LIHC cis rs9611519 0.780 rs9611546 chr22:41698542 C/G cg06634786 chr22:41940651 POLR3H -0.57 -6.57 -0.33 1.89e-10 Neuroticism; LIHC cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg18225595 chr11:63971243 STIP1 0.66 8.3 0.41 2.5e-15 Mean platelet volume; LIHC cis rs10193935 0.901 rs10171643 chr2:42532912 C/T cg27598129 chr2:42591480 NA -0.66 -10.16 -0.48 2.21e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs7613875 0.580 rs12634780 chr3:50043341 A/T cg24110177 chr3:50126178 RBM5 0.55 8.85 0.43 4.83e-17 Body mass index; LIHC cis rs2191566 1.000 rs390369 chr19:44506984 C/T cg20607764 chr19:44506953 ZNF230 0.44 7.1 0.36 7.45e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs3008870 1.000 rs975451 chr1:67480060 T/C cg02640540 chr1:67518911 SLC35D1 0.44 6.01 0.31 4.67e-9 Lymphocyte percentage of white cells; LIHC cis rs9948 1.000 rs1320146 chr2:97507727 T/C cg01990225 chr2:97406019 LMAN2L -0.59 -6.04 -0.31 4.02e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7772486 0.837 rs2474354 chr6:146323795 T/A cg23711669 chr6:146136114 FBXO30 0.57 10.01 0.48 7.43e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs2075371 0.796 rs1978504 chr7:134006933 C/T cg20476274 chr7:133979776 SLC35B4 -0.66 -9.25 -0.45 2.41e-18 Mean platelet volume; LIHC cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg02359409 chr6:42947317 PEX6 -0.46 -6.09 -0.31 2.96e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9916302 0.706 rs4516267 chr17:37471482 G/T cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg18306943 chr3:40428807 ENTPD3 0.35 6.09 0.31 3.1e-9 Renal cell carcinoma; LIHC cis rs67478160 0.634 rs2368559 chr14:104230535 C/T cg08213375 chr14:104286397 PPP1R13B 0.52 10.07 0.48 4.6e-21 Schizophrenia; LIHC cis rs933688 1.000 rs985434 chr5:90744509 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.2 0.66 3.29e-44 Smoking behavior; LIHC cis rs5769707 0.521 rs6009805 chr22:50058715 T/C cg07959070 chr22:50026188 C22orf34 -0.3 -7.22 -0.36 3.33e-12 Monocyte count;Monocyte percentage of white cells; LIHC trans rs1005277 0.528 rs2057228 chr10:38515766 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs13191362 0.810 rs66921603 chr6:162996982 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.92 0.3 7.85e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12744310 0.887 rs12026404 chr1:41801912 C/A cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg15383120 chr6:291909 DUSP22 -0.46 -6.24 -0.32 1.33e-9 Menopause (age at onset); LIHC cis rs34172651 0.517 rs36113933 chr16:24838862 A/G cg00152838 chr16:24741724 TNRC6A -0.53 -6.4 -0.33 4.99e-10 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs66559400 chr3:10012551 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs80282103 0.867 rs80254477 chr10:1077387 T/G cg08668510 chr10:1095578 IDI1 0.65 6.67 0.34 1.06e-10 Glomerular filtration rate (creatinine); LIHC cis rs7312933 0.934 rs11181289 chr12:42402342 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.73 0.34 7.01e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg02155528 chr15:90808716 NGRN -0.44 -6.11 -0.31 2.67e-9 Migraine with aura; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg05223897 chr7:65842437 NCRNA00174 -0.36 -6.14 -0.32 2.35e-9 Migraine with aura; LIHC cis rs6582630 0.502 rs1607876 chr12:38355750 T/C cg26384229 chr12:38710491 ALG10B 0.56 7.82 0.39 6.72e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg05890377 chr2:74357713 NA 0.46 8.5 0.42 6.04e-16 Gestational age at birth (maternal effect); LIHC cis rs743757 0.938 rs2236981 chr3:50488845 A/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.49 7.73 0.39 1.25e-13 Diastolic blood pressure; LIHC cis rs12586317 0.547 rs74243586 chr14:35477325 C/T cg05294307 chr14:35346193 BAZ1A -0.5 -7.42 -0.37 9.26e-13 Psoriasis; LIHC trans rs2243480 1.000 rs316329 chr7:65608416 A/C cg10756647 chr7:56101905 PSPH 1.08 13.21 0.58 1.84e-32 Diabetic kidney disease; LIHC trans rs4942242 0.640 rs17460861 chr13:44230078 C/G cg19169023 chr15:41853346 TYRO3 0.53 7.54 0.38 4.36e-13 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs2228479 0.681 rs10153055 chr16:89965842 C/T cg14709524 chr16:89940631 TCF25 0.51 6.39 0.33 5.36e-10 Skin colour saturation; LIHC cis rs4665809 1.000 rs2891490 chr2:26325927 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.72 -0.43 1.26e-16 Gut microbiome composition (summer); LIHC cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg01765077 chr12:122356316 WDR66 0.54 8.42 0.41 1.06e-15 Mean corpuscular volume; LIHC cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.83 -0.3 1.29e-8 Colorectal cancer; LIHC cis rs16854884 0.657 rs4611822 chr3:143735544 C/T cg06585982 chr3:143692056 C3orf58 0.54 7.06 0.36 9.48e-12 Economic and political preferences (feminism/equality); LIHC cis rs7762018 0.891 rs4716343 chr6:170143817 C/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.51 6.28 0.32 1e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg17340655 chr8:38088874 DDHD2 -0.36 -6.06 -0.31 3.59e-9 Eotaxin levels; LIHC cis rs2953174 0.529 rs3997219 chr2:241541619 T/C cg07929629 chr2:241523174 NA 0.54 6.73 0.34 7.11e-11 Bipolar disorder; LIHC cis rs9381040 0.748 rs9357348 chr6:41154232 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.4 -0.33 5.21e-10 Alzheimer's disease (late onset); LIHC cis rs9818758 0.607 rs5030795 chr3:49141116 C/T cg07636037 chr3:49044803 WDR6 -0.69 -7.47 -0.37 6.81e-13 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.43 7.36 0.37 1.39e-12 Bipolar disorder; LIHC cis rs4561483 0.551 rs1126889 chr16:12061910 C/G cg08843971 chr16:11963173 GSPT1 -0.3 -6.11 -0.31 2.74e-9 Testicular germ cell tumor; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg20295408 chr7:1910781 MAD1L1 -0.43 -6.26 -0.32 1.15e-9 Bipolar disorder and schizophrenia; LIHC cis rs13161895 1.000 rs34027780 chr5:179478891 C/A cg06664874 chr5:179499304 RNF130 0.62 7.62 0.38 2.56e-13 LDL cholesterol; LIHC cis rs2559856 0.935 rs7970952 chr12:102081577 C/T cg12924262 chr12:102091054 CHPT1 0.5 7.95 0.4 2.7e-14 Blood protein levels; LIHC cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6684514 1.000 rs10494304 chr1:156285764 C/G cg16558208 chr1:156270281 VHLL -0.53 -10.15 -0.48 2.55e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9733 0.596 rs6678013 chr1:150623285 T/G cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs9902453 0.904 rs4375718 chr17:28363642 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.76 -0.6 1.41e-34 Coffee consumption (cups per day); LIHC cis rs4728302 0.583 rs58955798 chr7:133158420 C/T cg10665199 chr7:133106180 EXOC4 0.52 8.71 0.43 1.32e-16 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11098499 0.874 rs6822498 chr4:120120183 T/C cg09307838 chr4:120376055 NA 0.52 7.74 0.39 1.16e-13 Corneal astigmatism; LIHC cis rs10751667 1.000 rs10794357 chr11:973374 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.44 0.53 6.8e-26 Alzheimer's disease (late onset); LIHC cis rs7100689 0.646 rs1340375 chr10:82129039 C/T cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs4957048 0.891 rs11960196 chr5:568857 C/A cg09021430 chr5:549028 NA -0.43 -8.85 -0.43 4.82e-17 Ulcerative colitis; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15573783 chr19:45927056 ERCC1 0.46 6.76 0.34 6.01e-11 Calcium levels; LIHC cis rs7833790 0.724 rs72603871 chr8:82754460 C/G cg27398817 chr8:82754497 SNX16 0.31 5.74 0.3 2.14e-8 Diastolic blood pressure; LIHC cis rs3796352 0.892 rs35076015 chr3:53026366 C/T cg07884673 chr3:53033167 SFMBT1 0.93 6.67 0.34 1.05e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7772486 0.764 rs2265471 chr6:146220250 G/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.86 -0.3 1.09e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs782590 0.517 rs13013133 chr2:55889466 G/A cg03859395 chr2:55845619 SMEK2 -0.48 -7.47 -0.37 6.58e-13 Metabolic syndrome; LIHC cis rs4665809 1.000 rs4665816 chr2:26305094 G/C cg04944784 chr2:26401820 FAM59B -0.64 -8.21 -0.41 4.74e-15 Gut microbiome composition (summer); LIHC cis rs459571 0.920 rs2520094 chr9:136919985 A/T cg13789015 chr9:136890014 NCRNA00094 0.44 7.87 0.39 4.84e-14 Platelet distribution width; LIHC cis rs2816062 0.813 rs2816053 chr1:18895819 A/G cg18795169 chr1:18902165 NA -0.8 -18.05 -0.7 1.24e-51 Urate levels in lean individuals; LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg02782426 chr3:40428986 ENTPD3 0.34 6.42 0.33 4.5e-10 Renal cell carcinoma; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.97 0.8 4.54e-79 Prudent dietary pattern; LIHC cis rs1577917 1.000 rs10455449 chr6:86592226 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.17 -0.36 4.69e-12 Response to antipsychotic treatment; LIHC trans rs10411161 0.702 rs75647161 chr19:52398984 T/C cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs765787 0.530 rs12917187 chr15:45538297 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs2842992 0.830 rs1998365 chr6:160179535 A/T cg19482086 chr6:160211437 TCP1;MRPL18 0.69 11.94 0.54 1.06e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs208520 0.690 rs851458 chr6:66813279 T/G cg07460842 chr6:66804631 NA -0.86 -9.39 -0.45 8.54e-19 Exhaled nitric oxide output; LIHC cis rs9910055 0.530 rs7222349 chr17:42304644 C/T cg08499158 chr17:42289980 UBTF -0.48 -7.83 -0.39 6.36e-14 Total body bone mineral density; LIHC cis rs4820294 1.000 rs739139 chr22:38067011 C/G cg26138144 chr22:38071188 LGALS1 0.76 14.22 0.61 2.25e-36 Fat distribution (HIV); LIHC cis rs1865760 1.000 rs7770139 chr6:25925823 A/G cg17691542 chr6:26056736 HIST1H1C 0.4 5.98 0.31 5.68e-9 Height; LIHC cis rs10751667 0.857 rs7481221 chr11:966813 G/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs2576037 0.583 rs641366 chr18:44430326 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.98 0.51 3.15e-24 Personality dimensions; LIHC cis rs9308433 0.529 rs17022608 chr1:214500907 A/C cg06198575 chr1:214491504 SMYD2 0.54 5.81 0.3 1.45e-8 IgG glycosylation; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 9.15e-15 Prudent dietary pattern; LIHC cis rs2153535 0.542 rs1120393 chr6:8486890 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs637571 0.510 rs3892696 chr11:65582341 G/C cg26695010 chr11:65641043 EFEMP2 0.44 6.02 0.31 4.44e-9 Eosinophil percentage of white cells; LIHC cis rs8103278 0.507 rs4802276 chr19:46260748 T/C cg11657440 chr19:46296263 DMWD 0.68 12.58 0.56 4.34e-30 Coronary artery disease; LIHC cis rs2839186 0.934 rs17182538 chr21:47705673 C/A cg12379764 chr21:47803548 PCNT -0.6 -8.72 -0.43 1.2e-16 Testicular germ cell tumor; LIHC cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.52 0.53 3.63e-26 Alzheimer's disease; LIHC cis rs9399135 0.967 rs7766189 chr6:135353851 A/C cg24558204 chr6:135376177 HBS1L 0.43 7.16 0.36 4.85e-12 Red blood cell count; LIHC cis rs4891159 0.790 rs7234653 chr18:74111988 C/T cg24786174 chr18:74118243 ZNF516 -0.8 -14.62 -0.62 5.86e-38 Longevity; LIHC cis rs7772486 0.790 rs2265474 chr6:146182092 G/A cg05347473 chr6:146136440 FBXO30 0.39 6.21 0.32 1.58e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3790645 1.000 rs34062688 chr1:26887150 A/G cg17456097 chr1:26900765 RPS6KA1 0.43 6.2 0.32 1.64e-9 Glucose homeostasis traits; LIHC cis rs7116495 0.609 rs60054591 chr11:71825687 G/A cg10381502 chr11:71823885 C11orf51 1.06 9.3 0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs72627123 0.867 rs112464051 chr14:74483975 C/T cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.75 0.3 1.97e-8 Morning vs. evening chronotype; LIHC cis rs1707322 1.000 rs4660335 chr1:46474718 C/T cg03146154 chr1:46216737 IPP 0.47 7.4 0.37 1.1e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs916888 0.821 rs199512 chr17:44857352 T/C cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10504229 0.861 rs67966192 chr8:58188172 A/C cg21724239 chr8:58056113 NA 0.45 6.01 0.31 4.68e-9 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.586 rs11146503 chr10:134565388 T/C cg13271783 chr10:134563150 INPP5A -0.57 -6.8 -0.35 4.6e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg10295955 chr4:187884368 NA -0.96 -22.18 -0.77 3.68e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg17747265 chr1:1875780 NA -0.6 -11.64 -0.53 1.31e-26 Body mass index; LIHC cis rs921968 0.541 rs485975 chr2:219374250 C/T cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7044106 0.762 rs1411158 chr9:123464804 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.97 0.51 3.31e-24 Hip circumference adjusted for BMI; LIHC cis rs11958404 0.932 rs72816566 chr5:157427613 G/A cg05962755 chr5:157440814 NA 0.92 10.57 0.5 8.6e-23 IgG glycosylation; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg12432846 chr1:85741899 BCL10 -0.47 -6.51 -0.33 2.73e-10 Electroencephalogram traits; LIHC cis rs10894308 0.543 rs7106928 chr11:130809259 T/G cg12179176 chr11:130786555 SNX19 0.68 9.66 0.46 1.08e-19 Schizophrenia; LIHC cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.56 -9.41 -0.45 7.51e-19 Prudent dietary pattern; LIHC cis rs2072438 0.505 rs7034074 chr9:123923029 A/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.45 6.29 0.32 9.96e-10 Rheumatoid arthritis; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg09143319 chr8:144997224 PLEC1 0.45 6.58 0.34 1.72e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs17401966 1.000 rs6700866 chr1:10306038 A/G cg19773385 chr1:10388646 KIF1B -0.47 -8.18 -0.4 5.75e-15 Hepatocellular carcinoma; LIHC cis rs2404602 0.692 rs67570291 chr15:77020502 T/C cg03037974 chr15:76606532 NA 0.74 14.68 0.62 3.61e-38 Blood metabolite levels; LIHC cis rs35306767 0.953 rs35174953 chr10:961191 C/A cg20503657 chr10:835505 NA 0.9 10.77 0.5 1.76e-23 Eosinophil percentage of granulocytes; LIHC cis rs66887589 0.934 rs4834792 chr4:120555696 T/A cg09307838 chr4:120376055 NA -0.46 -6.76 -0.34 6.13e-11 Diastolic blood pressure; LIHC cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg24531977 chr5:56204891 C5orf35 -0.59 -8.34 -0.41 1.83e-15 Initial pursuit acceleration; LIHC cis rs12497850 0.931 rs7627404 chr3:48819668 A/C cg20833759 chr3:49053208 WDR6;DALRD3 0.39 5.72 0.3 2.28e-8 Parkinson's disease; LIHC cis rs9858542 1.000 rs9822268 chr3:49719729 G/A cg03060546 chr3:49711283 APEH -0.64 -8.72 -0.43 1.22e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1395 0.626 rs72817537 chr2:27497549 G/A cg22903471 chr2:27725779 GCKR -0.43 -6.06 -0.31 3.54e-9 Blood metabolite levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg23640757 chr6:7889014 TXNDC5 0.37 6.24 0.32 1.3e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7216064 1.000 rs1976053 chr17:65833002 C/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.71 -0.46 7.79e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs60871478 0.945 rs62432254 chr7:804175 C/T cg04727924 chr7:799746 HEATR2 -0.58 -8.61 -0.42 2.7e-16 Cerebrospinal P-tau181p levels; LIHC cis rs853679 0.517 rs3757187 chr6:28107654 T/C cg23485639 chr6:28045615 ZNF165 0.44 5.74 0.3 2.08e-8 Depression; LIHC cis rs16828019 0.704 rs4996176 chr1:41488168 G/T cg03387723 chr1:41708464 SCMH1 -0.4 -6.27 -0.32 1.07e-9 Intelligence (multi-trait analysis); LIHC cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.38 -0.37 1.2e-12 Bipolar disorder; LIHC cis rs7582720 1.000 rs72936309 chr2:204040296 G/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs5769765 0.657 rs8136116 chr22:50256886 T/A cg22709217 chr22:50311962 ALG12;CRELD2 0.58 5.81 0.3 1.44e-8 Schizophrenia; LIHC cis rs7208859 0.623 rs56095789 chr17:29060170 A/G cg14067834 chr17:29058358 SUZ12P 0.68 6.79 0.34 5.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11671005 0.695 rs8106061 chr19:58917990 G/C cg00825309 chr19:58991885 ZNF446 -0.96 -14.75 -0.62 1.93e-38 Mean platelet volume; LIHC cis rs4975709 1.000 rs2279588 chr5:1878021 G/A cg15595755 chr5:1867978 NA 0.34 6.27 0.32 1.08e-9 Cardiovascular disease risk factors; LIHC cis rs12477438 0.520 rs13009147 chr2:99803998 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.2 0.61 2.58e-36 Chronic sinus infection; LIHC cis rs3106136 0.967 rs282448 chr4:95141411 T/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.18 -0.4 5.45e-15 Capecitabine sensitivity; LIHC cis rs244293 0.831 rs12450607 chr17:53127255 C/G cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.45 0.37 7.89e-13 Menarche (age at onset); LIHC cis rs2635047 1.000 rs2635043 chr18:44679769 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.45 6.03 0.31 4.21e-9 Educational attainment; LIHC cis rs10911232 0.507 rs10797816 chr1:182998486 A/T ch.1.3577855R chr1:183094577 LAMC1 0.58 10.11 0.48 3.31e-21 Hypertriglyceridemia; LIHC cis rs6502050 0.865 rs74480314 chr17:80117716 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs7119038 0.818 rs73003215 chr11:118649512 G/A cg19308663 chr11:118741387 NA 0.4 6.19 0.32 1.72e-9 Sjögren's syndrome; LIHC cis rs7267979 0.509 rs6115218 chr20:25566485 A/G cg21995068 chr20:25989032 LOC100134868 -0.51 -7.64 -0.38 2.25e-13 Liver enzyme levels (alkaline phosphatase); LIHC cis rs3008870 0.917 rs12044492 chr1:67461667 T/C cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs7089973 0.624 rs17586888 chr10:116598121 T/C cg03647239 chr10:116582469 FAM160B1 0.44 6.58 0.34 1.74e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs700651 0.789 rs10497812 chr2:198911245 A/G cg00792783 chr2:198669748 PLCL1 -0.45 -6.49 -0.33 3.1e-10 Intracranial aneurysm; LIHC cis rs11764590 0.694 rs10276536 chr7:2086960 C/T cg23422044 chr7:1970798 MAD1L1 -0.49 -7.73 -0.39 1.2e-13 Neuroticism; LIHC cis rs7617773 0.851 rs13068288 chr3:48331751 A/T cg11946769 chr3:48343235 NME6 0.86 10.96 0.51 3.74e-24 Coronary artery disease; LIHC cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg04944784 chr2:26401820 FAM59B 0.71 9.3 0.45 1.76e-18 Gut microbiome composition (summer); LIHC cis rs3815700 1.000 rs8109990 chr19:33095636 A/G cg02997394 chr19:33096574 ANKRD27 0.73 9.38 0.45 9.36e-19 Eosinophilic esophagitis; LIHC cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg11890956 chr21:40555474 PSMG1 0.99 13.54 0.59 1.01e-33 Cognitive function; LIHC cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9911578 0.757 rs4793954 chr17:56629527 G/T cg12560992 chr17:57184187 TRIM37 -0.81 -12.44 -0.56 1.43e-29 Intelligence (multi-trait analysis); LIHC cis rs11031096 0.727 rs2056853 chr11:4142172 C/T cg18678763 chr11:4115507 RRM1 -0.52 -8.04 -0.4 1.47e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1005277 0.579 rs2474586 chr10:38418882 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.82e-23 Extrinsic epigenetic age acceleration; LIHC cis rs7584330 0.518 rs78856668 chr2:238438055 A/C cg08992911 chr2:238395768 MLPH 0.56 6.21 0.32 1.51e-9 Prostate cancer; LIHC cis rs10792665 1.000 rs4944419 chr11:82646964 A/G cg24227371 chr11:82718527 RAB30 0.31 6.95 0.35 1.9e-11 Obesity-related traits; LIHC cis rs7909074 1.000 rs7909074 chr10:45395839 G/A cg04218760 chr10:45406644 TMEM72 -0.23 -7.31 -0.37 1.96e-12 Mean corpuscular volume; LIHC cis rs10089 1.000 rs7713877 chr5:127428825 G/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.26e-11 Ileal carcinoids; LIHC cis rs8180040 0.845 rs295441 chr3:47333295 T/A cg27129171 chr3:47204927 SETD2 0.64 11.01 0.51 2.46e-24 Colorectal cancer; LIHC cis rs72781680 0.611 rs56326157 chr2:24312407 T/C cg06627628 chr2:24431161 ITSN2 -0.65 -7.48 -0.38 6.21e-13 Lymphocyte counts; LIHC cis rs4268898 0.662 rs9917315 chr2:24431501 C/A cg06627628 chr2:24431161 ITSN2 -0.73 -9.61 -0.46 1.67e-19 Asthma; LIHC cis rs4660306 0.961 rs3748643 chr1:45965703 G/T cg03123370 chr1:45965343 CCDC163P;MMACHC -0.65 -7.91 -0.39 3.51e-14 Homocysteine levels; LIHC cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg06634786 chr22:41940651 POLR3H -0.82 -8.77 -0.43 8.72e-17 Vitiligo; LIHC cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.56 0.53 2.65e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1881396 0.947 rs77350364 chr2:27866139 A/G cg27432699 chr2:27873401 GPN1 0.51 7.87 0.39 4.73e-14 Nonalcoholic fatty liver disease; LIHC trans rs7618501 0.501 rs35275715 chr3:49959148 A/G cg21659725 chr3:3221576 CRBN 0.56 8.27 0.41 2.93e-15 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg14828511 chr1:107599125 PRMT6 0.43 6.14 0.32 2.31e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7309 0.935 rs11884495 chr2:162059969 A/T cg13854012 chr2:162103682 NA -0.35 -6.52 -0.33 2.47e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs7116495 1.000 rs4945435 chr11:71759219 C/T cg26138937 chr11:71823887 C11orf51 -0.76 -7.53 -0.38 4.68e-13 Severe influenza A (H1N1) infection; LIHC cis rs7772486 0.790 rs2814880 chr6:146208937 T/G cg23711669 chr6:146136114 FBXO30 0.63 11.06 0.51 1.62e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2120019 0.505 rs77456790 chr15:75330095 G/T cg09165964 chr15:75287851 SCAMP5 -0.63 -7.88 -0.39 4.43e-14 Blood trace element (Zn levels); LIHC cis rs6088590 1.000 rs6120705 chr20:33313740 T/C cg06115741 chr20:33292138 TP53INP2 0.61 8.78 0.43 8.03e-17 Coronary artery disease; LIHC cis rs2637266 1.000 rs7896379 chr10:78366247 C/T cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.17e-8 Pulmonary function; LIHC cis rs9942416 0.601 rs40059 chr5:74964582 A/G cg19683494 chr5:74908142 NA -0.62 -8.8 -0.43 6.78e-17 Age-related disease endophenotypes; LIHC cis rs11971779 0.616 rs1133068 chr7:139053143 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC trans rs12620999 1.000 rs4558538 chr2:238055975 C/T cg15676719 chr1:167598521 RCSD1 -0.37 -6.51 -0.33 2.67e-10 Systemic lupus erythematosus; LIHC trans rs2579103 0.767 rs2247166 chr12:90661266 C/T cg00091569 chr3:40428383 ENTPD3 0.37 6.07 0.31 3.42e-9 Body mass index; LIHC cis rs4517514 0.509 rs11018894 chr11:89904238 C/A cg05041596 chr11:89867385 NAALAD2 0.42 6.77 0.34 5.49e-11 Trans fatty acid levels; LIHC cis rs11671005 0.736 rs11668201 chr19:59003632 A/T cg25952890 chr19:58913133 NA 0.61 6.3 0.32 9.37e-10 Mean platelet volume; LIHC trans rs561341 0.941 rs72825736 chr17:30330286 G/A cg20587970 chr11:113659929 NA -1.41 -12.24 -0.55 7.93e-29 Hip circumference adjusted for BMI; LIHC cis rs3736485 0.844 rs8041197 chr15:51865877 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.31 -0.32 8.45e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2979489 0.945 rs12548554 chr8:30346544 G/A cg26383811 chr8:30366931 RBPMS -0.75 -12.11 -0.55 2.51e-28 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs798554 0.757 rs1183085 chr7:2875570 G/A cg19717773 chr7:2847554 GNA12 -0.42 -6.33 -0.32 7.86e-10 Height; LIHC cis rs78545713 0.536 rs2179516 chr6:26229411 C/T cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs6912958 0.559 rs369674 chr6:88043402 C/G cg04972856 chr6:88032051 C6orf162;GJB7 -0.31 -6.04 -0.31 3.98e-9 Monocyte percentage of white cells; LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg26338869 chr17:61819248 STRADA 0.61 8.84 0.43 5.28e-17 Prudent dietary pattern; LIHC cis rs4969178 0.641 rs4969141 chr17:76391653 C/T cg05887092 chr17:76393375 PGS1 0.35 6.8 0.35 4.73e-11 HDL cholesterol levels; LIHC cis rs9911578 0.740 rs368243 chr17:56708979 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.6 8.73 0.43 1.15e-16 Intelligence (multi-trait analysis); LIHC cis rs7129220 0.588 rs7129047 chr11:10143942 C/A cg01453529 chr11:10209919 SBF2 -0.38 -6.71 -0.34 8.04e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs35306767 0.714 rs11250228 chr10:1074887 A/G cg26597838 chr10:835615 NA 0.63 6.98 0.35 1.54e-11 Eosinophil percentage of granulocytes; LIHC cis rs6933660 0.745 rs9397405 chr6:151736084 G/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.54 -8.23 -0.41 3.95e-15 Menarche (age at onset); LIHC cis rs4819052 0.851 rs2838856 chr21:46680766 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 11.22 0.52 4.54e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs57221529 0.766 rs72706608 chr5:559203 C/T cg09021430 chr5:549028 NA -0.46 -9.15 -0.44 5.13e-18 Lung disease severity in cystic fibrosis; LIHC cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.07 0.31 3.47e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7772486 0.806 rs2265477 chr6:146212338 T/C cg23711669 chr6:146136114 FBXO30 0.58 10.3 0.49 7.48e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs881375 0.678 rs3761846 chr9:123689597 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 6.18 0.32 1.87e-9 Rheumatoid arthritis; LIHC cis rs7216064 0.628 rs62084702 chr17:66043157 C/T cg12091567 chr17:66097778 LOC651250 0.86 14.74 0.62 2.01e-38 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg11062466 chr8:58055876 NA 0.43 6.26 0.32 1.16e-9 Developmental language disorder (linguistic errors); LIHC cis rs9303280 0.901 rs7216389 chr17:38069949 C/T cg11212589 chr17:38028394 ZPBP2 -0.34 -6.79 -0.34 4.84e-11 Self-reported allergy; LIHC cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg09323728 chr8:95962352 TP53INP1 -0.3 -6.48 -0.33 3.15e-10 Type 2 diabetes; LIHC cis rs9291683 0.632 rs7679916 chr4:10042160 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.63e-13 Bone mineral density; LIHC cis rs7474896 1.000 rs61858629 chr10:38014770 G/A cg25427524 chr10:38739819 LOC399744 -0.5 -6.29 -0.32 9.83e-10 Obesity (extreme); LIHC cis rs13108904 0.846 rs3775100 chr4:1225106 T/C cg05665937 chr4:1216051 CTBP1 0.52 7.83 0.39 6.05e-14 Obesity-related traits; LIHC cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg19318889 chr4:1322082 MAEA 0.43 6.5 0.33 2.8e-10 Longevity; LIHC cis rs56104184 0.723 rs73063524 chr19:49409004 T/C cg21252483 chr19:49399788 TULP2 -1.0 -11.73 -0.54 6.22e-27 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg26338869 chr17:61819248 STRADA 0.53 7.16 0.36 5.11e-12 Height; LIHC cis rs6964587 0.967 rs10953063 chr7:91576958 A/G cg17063962 chr7:91808500 NA -1.02 -19.48 -0.73 2.17e-57 Breast cancer; LIHC cis rs6582630 0.615 rs3914894 chr12:38480280 C/T cg26384229 chr12:38710491 ALG10B -0.44 -6.16 -0.32 2.06e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg03806693 chr22:41940476 POLR3H 1.08 13.09 0.58 4.97e-32 Vitiligo; LIHC cis rs8014204 0.935 rs10141438 chr14:75354600 A/G cg08847533 chr14:75593920 NEK9 -0.38 -6.42 -0.33 4.53e-10 Caffeine consumption; LIHC cis rs875971 0.964 rs6978429 chr7:65959876 T/G cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.54e-9 Aortic root size; LIHC cis rs7020830 0.931 rs13295115 chr9:37157964 T/G cg14294708 chr9:37120828 ZCCHC7 1.19 25.49 0.81 4.62e-81 Schizophrenia; LIHC cis rs12474201 0.569 rs13411633 chr2:46932666 A/G cg06386533 chr2:46925753 SOCS5 0.5 5.99 0.31 5.32e-9 Height; LIHC cis rs9457247 0.935 rs427824 chr6:167403918 T/G cg07741184 chr6:167504864 NA 0.32 7.36 0.37 1.34e-12 Crohn's disease; LIHC cis rs5769765 1.000 rs1033665 chr22:50252127 A/G cg09182678 chr22:50328711 NA -0.38 -5.86 -0.3 1.09e-8 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18450294 chr17:423235 VPS53 -0.42 -6.26 -0.32 1.18e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4407350 0.870 rs5764873 chr22:44908153 G/A cg26276947 chr22:44892394 LDOC1L 0.35 6.79 0.34 4.92e-11 Intelligence (multi-trait analysis); LIHC cis rs611744 0.647 rs1609472 chr8:109269232 T/G cg18478394 chr8:109455254 TTC35 0.42 7.21 0.36 3.52e-12 Dupuytren's disease; LIHC cis rs4665809 1.000 rs6546736 chr2:26293878 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.7 8.62 0.42 2.58e-16 Gut microbiome composition (summer); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg21496518 chr3:15374154 SH3BP5 -0.44 -6.31 -0.32 8.77e-10 Hepatitis; LIHC cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6426558 0.537 rs2718193 chr1:227404672 C/G cg10327440 chr1:227177885 CDC42BPA 0.41 6.44 0.33 4.12e-10 Neutrophil percentage of white cells; LIHC cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.11 -0.61 6.26e-36 Alzheimer's disease; LIHC cis rs1957429 0.808 rs4902325 chr14:65330843 A/G cg23373153 chr14:65346875 NA -0.78 -11.1 -0.51 1.21e-24 Pediatric areal bone mineral density (radius); LIHC cis rs7927592 0.763 rs11822059 chr11:68300822 T/G cg20283391 chr11:68216788 NA -0.38 -6.04 -0.31 4.12e-9 Total body bone mineral density; LIHC cis rs600806 0.850 rs3768493 chr1:109935505 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs483180 0.531 rs539708 chr1:120208503 G/T cg19096424 chr1:120255104 PHGDH -0.62 -7.9 -0.39 3.83e-14 Macular telangiectasia type 2; LIHC trans rs11098499 0.913 rs35271032 chr4:120156659 C/T cg25214090 chr10:38739885 LOC399744 0.54 8.11 0.4 8.92e-15 Corneal astigmatism; LIHC cis rs1113500 0.897 rs55980437 chr1:108639498 G/A cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.91e-12 Growth-regulated protein alpha levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10964577 chr17:15160725 PMP22 0.46 6.31 0.32 8.65e-10 Lung function (FEV1/FVC); LIHC cis rs7772486 0.846 rs2144478 chr6:146381445 A/G cg23711669 chr6:146136114 FBXO30 0.58 10.36 0.49 4.62e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.861 rs57314710 chr8:58196051 T/C cg20607798 chr8:58055168 NA 0.59 6.85 0.35 3.44e-11 Developmental language disorder (linguistic errors); LIHC trans rs2243480 1.000 rs781157 chr7:65478311 G/A cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs8180040 0.620 rs11709660 chr3:47074927 G/A cg16586182 chr3:47516702 SCAP 0.47 8.57 0.42 3.7e-16 Colorectal cancer; LIHC cis rs2836950 0.502 rs12627205 chr21:40630027 C/T cg11890956 chr21:40555474 PSMG1 -0.44 -7.15 -0.36 5.36e-12 Menarche (age at onset); LIHC cis rs3008870 1.000 rs2815351 chr1:67477980 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.9 14.6 0.62 7e-38 Lymphocyte percentage of white cells; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC trans rs783540 0.867 rs11855735 chr15:83296545 A/T cg18393722 chr15:85113863 UBE2QP1 0.36 6.17 0.32 1.88e-9 Schizophrenia; LIHC cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg18876405 chr7:65276391 NA 0.55 9.36 0.45 1.07e-18 Calcium levels; LIHC cis rs17106184 0.582 rs60848584 chr1:51010143 C/T cg07174182 chr1:51127561 FAF1 -0.68 -7.06 -0.36 9.61e-12 Type 2 diabetes; LIHC cis rs1862618 0.671 rs173763 chr5:56225418 G/A cg24531977 chr5:56204891 C5orf35 -0.54 -7.83 -0.39 6.27e-14 Initial pursuit acceleration; LIHC trans rs7618501 0.633 rs35065728 chr3:50009176 T/C cg21659725 chr3:3221576 CRBN 0.67 10.92 0.51 5.2e-24 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs6443276 chr3:10008905 C/A cg13047869 chr3:10149882 C3orf24 0.43 5.92 0.31 7.68e-9 Alzheimer's disease; LIHC cis rs9916302 0.904 rs11654018 chr17:37703740 C/T cg00129232 chr17:37814104 STARD3 0.4 6.33 0.32 7.76e-10 Glomerular filtration rate (creatinine); LIHC cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg04317338 chr11:64019027 PLCB3 0.87 10.96 0.51 3.84e-24 Mean platelet volume; LIHC cis rs9309711 0.689 rs4535075 chr2:3481716 T/C cg04359351 chr2:3481828 TTC15 0.28 5.95 0.31 6.72e-9 Neurofibrillary tangles; LIHC cis rs7762018 0.891 rs3088346 chr6:170149793 T/C cg19338460 chr6:170058176 WDR27 -0.37 -5.76 -0.3 1.9e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs56146971 0.703 rs79190905 chr14:91848149 C/T cg16433844 chr14:91963127 SMEK1 -0.56 -5.83 -0.3 1.25e-8 Alzheimer disease and age of onset; LIHC cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg12310025 chr6:25882481 NA -0.63 -7.85 -0.39 5.38e-14 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.935 rs9390329 chr6:145828026 T/C cg23711669 chr6:146136114 FBXO30 0.56 10.32 0.49 6.24e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs4404802 chr6:8442052 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs644799 0.965 rs3789960 chr11:95509037 C/G cg25478527 chr11:95522999 CEP57;FAM76B 0.41 5.72 0.3 2.3e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs13108904 0.934 rs13134106 chr4:1302902 A/G cg05665937 chr4:1216051 CTBP1 0.44 5.79 0.3 1.62e-8 Obesity-related traits; LIHC cis rs11991744 0.681 rs7387855 chr8:124665211 C/T cg22342100 chr8:124666123 KLHL38 -0.39 -6.03 -0.31 4.37e-9 Electrocardiographic traits; LIHC cis rs9814567 1.000 rs1880376 chr3:134270347 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10791323 0.660 rs10791332 chr11:133732150 A/G cg15485101 chr11:133734466 NA 0.25 5.9 0.3 8.52e-9 Childhood ear infection; LIHC cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg00612595 chr21:47717864 NA -0.38 -6.18 -0.32 1.87e-9 Testicular germ cell tumor; LIHC cis rs6835098 0.924 rs2332669 chr4:174163398 G/A cg27433088 chr4:174089019 GALNT7 0.36 6.21 0.32 1.55e-9 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs7635838 0.596 rs4684765 chr3:11261085 G/C cg00170343 chr3:11313890 ATG7 0.53 8.11 0.4 8.97e-15 HDL cholesterol; LIHC cis rs17685 0.753 rs13240404 chr7:75675719 C/T cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.29 0.32 9.72e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3820500 0.543 rs1290549 chr1:118051748 C/G cg20383390 chr1:117909022 MAN1A2 -0.47 -6.01 -0.31 4.66e-9 Pneumonia; LIHC cis rs425277 0.917 rs78395918 chr1:2045876 G/A cg24578937 chr1:2090814 PRKCZ 0.45 7.39 0.37 1.13e-12 Height; LIHC cis rs7223966 1.000 rs11658740 chr17:61751069 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.57 0.33 1.92e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs11169225 0.906 rs3782319 chr12:50345079 G/A cg04450003 chr12:50355995 AQP5 0.6 7.76 0.39 9.8e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg05484376 chr2:27715224 FNDC4 0.36 6.16 0.32 2.07e-9 Total body bone mineral density; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18594562 chr20:57797677 ZNF831 0.48 6.38 0.33 5.69e-10 Lung function (FEV1/FVC); LIHC cis rs12188164 0.543 rs2672757 chr5:454732 A/G cg00049323 chr5:472564 LOC25845 0.35 5.82 0.3 1.39e-8 Cystic fibrosis severity; LIHC cis rs60871478 0.898 rs4720929 chr7:808009 T/C cg04727924 chr7:799746 HEATR2 -0.58 -8.6 -0.42 2.86e-16 Cerebrospinal P-tau181p levels; LIHC trans rs2243480 1.000 rs1039664 chr7:65449716 T/G cg10756647 chr7:56101905 PSPH 1.11 13.56 0.59 7.83e-34 Diabetic kidney disease; LIHC cis rs11122272 0.735 rs2749723 chr1:231493302 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.22 0.45 3.03e-18 Hemoglobin concentration; LIHC cis rs10463316 0.894 rs6864722 chr5:150752942 G/A cg03212797 chr5:150827313 SLC36A1 -0.42 -6.26 -0.32 1.18e-9 Metabolite levels (Pyroglutamine); LIHC cis rs61542988 0.797 rs4329182 chr7:22882621 C/T cg11367502 chr7:22862612 TOMM7 0.56 9.74 0.47 6.1e-20 Fibrinogen levels; LIHC cis rs422249 0.512 rs174574 chr11:61600342 A/C cg27386326 chr11:61587980 NA -0.69 -14.55 -0.62 1.17e-37 Trans fatty acid levels; LIHC cis rs9902453 0.935 rs9905950 chr17:28431198 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.08 0.51 1.4e-24 Coffee consumption (cups per day); LIHC cis rs679087 1.000 rs672107 chr12:29917266 T/A cg14258853 chr12:29935411 TMTC1 -0.5 -7.82 -0.39 6.65e-14 Schizophrenia; LIHC cis rs867186 0.614 rs117065834 chr20:33426568 G/A cg08999081 chr20:33150536 PIGU 0.63 5.94 0.31 6.97e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg00710249 chr16:2144849 PKD1 0.38 6.1 0.31 2.91e-9 Eotaxin levels; LIHC cis rs798554 0.679 rs13230995 chr7:2887284 G/A cg04166393 chr7:2884313 GNA12 0.54 8.58 0.42 3.38e-16 Height; LIHC cis rs763014 0.966 rs4984903 chr16:680695 A/G cg07343612 chr16:622815 PIGQ -0.86 -14.95 -0.63 2.94e-39 Height; LIHC cis rs7116495 0.609 rs2508860 chr11:71805052 C/T cg26138937 chr11:71823887 C11orf51 1.32 10.32 0.49 6.52e-22 Severe influenza A (H1N1) infection; LIHC cis rs9486719 1.000 rs2971603 chr6:97035418 C/T cg06623918 chr6:96969491 KIAA0776 -0.69 -7.95 -0.4 2.69e-14 Migraine;Coronary artery disease; LIHC cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg18876405 chr7:65276391 NA 0.56 9.33 0.45 1.34e-18 Aortic root size; LIHC cis rs4665809 1.000 rs4665817 chr2:26305167 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.76 -9.51 -0.46 3.55e-19 Gut microbiome composition (summer); LIHC cis rs2742417 1.000 rs2742417 chr3:45731451 C/T cg04837898 chr3:45731254 SACM1L -0.36 -5.8 -0.3 1.5e-8 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs921968 0.541 rs514356 chr2:219375018 C/T cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs10911232 0.507 rs4652763 chr1:182994084 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs2832191 0.935 rs67287920 chr21:30523519 C/A cg08807101 chr21:30365312 RNF160 -0.49 -7.82 -0.39 6.78e-14 Dental caries; LIHC trans rs7504990 0.708 rs35002729 chr18:50379832 C/T cg08535148 chr4:26321143 RBPJ 0.56 6.9 0.35 2.5e-11 Gallbladder cancer; LIHC cis rs12086130 0.892 rs72906818 chr1:51470403 T/G cg07174182 chr1:51127561 FAF1 -0.82 -8.83 -0.43 5.69e-17 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg00149659 chr3:10157352 C3orf10 0.69 7.1 0.36 7.14e-12 Alzheimer's disease; LIHC cis rs1801251 0.778 rs2675957 chr2:233754364 C/T cg08000102 chr2:233561755 GIGYF2 -0.72 -10.33 -0.49 5.89e-22 Coronary artery disease; LIHC trans rs6598955 0.671 rs12068212 chr1:26612935 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.75 -8.73 -0.43 1.14e-16 Obesity-related traits; LIHC cis rs17125944 0.556 rs7152229 chr14:53313405 T/C cg00686598 chr14:53173677 PSMC6 -0.88 -10.29 -0.49 7.92e-22 Alzheimer's disease (late onset); LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg06951627 chr6:26196580 NA 0.53 6.34 0.32 7.09e-10 Gout;Renal underexcretion gout; LIHC cis rs1348850 0.958 rs4528793 chr2:178464271 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.29 0.52 2.45e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs506338 0.517 rs490192 chr11:64471369 C/T cg03263716 chr11:64435066 NRXN2 0.34 7.23 0.36 3.1e-12 Body mass index;Urate levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22874627 chr3:31575329 STT3B 0.48 6.75 0.34 6.51e-11 Pancreatic cancer; LIHC cis rs11190604 0.767 rs10883479 chr10:102162860 A/G cg07080220 chr10:102295463 HIF1AN 0.45 6.29 0.32 9.54e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs5769707 0.681 rs2071902 chr22:50034538 G/C cg01652190 chr22:50026171 C22orf34 -0.35 -7.69 -0.38 1.59e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2303745 0.589 rs1465576 chr19:17398487 G/A cg10664184 chr19:17420304 DDA1 0.46 5.88 0.3 9.65e-9 Systemic lupus erythematosus; LIHC cis rs597539 0.652 rs559032 chr11:68710847 G/T cg04772025 chr11:68637568 NA 0.49 6.37 0.33 6.2e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2354432 0.556 rs34602039 chr1:146850972 G/A cg25205988 chr1:146714368 CHD1L -0.84 -9.5 -0.46 3.87e-19 Mitochondrial DNA levels; LIHC cis rs6424115 0.867 rs11588187 chr1:24145047 T/A cg10978503 chr1:24200527 CNR2 0.37 8.73 0.43 1.16e-16 Immature fraction of reticulocytes; LIHC cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg18357526 chr6:26021779 HIST1H4A 1.05 15.68 0.65 4e-42 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.565 rs4904681 chr14:90835566 A/T cg04374321 chr14:90722782 PSMC1 -0.48 -7.06 -0.36 9.55e-12 Mortality in heart failure; LIHC cis rs61041384 0.661 rs74917517 chr12:123688805 C/T cg00376283 chr12:123451042 ABCB9 -0.55 -6.14 -0.32 2.28e-9 Schizophrenia; LIHC cis rs9527 0.615 rs11191485 chr10:104729816 G/C cg15744005 chr10:104629667 AS3MT -0.3 -6.03 -0.31 4.35e-9 Arsenic metabolism; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.87 0.39 4.61e-14 Prudent dietary pattern; LIHC cis rs10751667 0.643 rs11246344 chr11:933783 A/C cg11406765 chr11:980039 AP2A2 -0.35 -5.78 -0.3 1.69e-8 Alzheimer's disease (late onset); LIHC cis rs12477438 0.520 rs11695751 chr2:99708247 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.7 0.62 2.96e-38 Chronic sinus infection; LIHC cis rs12477438 0.798 rs12473029 chr2:99637961 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.85 -11.31 -0.52 2.1e-25 Chronic sinus infection; LIHC cis rs6952808 0.862 rs4721167 chr7:1933224 C/T cg20295408 chr7:1910781 MAD1L1 -0.5 -7.06 -0.36 9.19e-12 Bipolar disorder and schizophrenia; LIHC cis rs244293 0.965 rs2628318 chr17:53210312 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs870825 0.616 rs4416519 chr4:185639502 T/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs1552244 0.554 rs17050705 chr3:10046398 G/C cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs611744 0.870 rs596703 chr8:109160146 A/G cg21045802 chr8:109455806 TTC35 -0.59 -10.11 -0.48 3.33e-21 Dupuytren's disease; LIHC cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg18357526 chr6:26021779 HIST1H4A 0.57 7.77 0.39 8.99e-14 Blood metabolite levels; LIHC cis rs7927592 0.763 rs1193699 chr11:68249480 C/G cg20283391 chr11:68216788 NA -0.38 -6.1 -0.31 2.83e-9 Total body bone mineral density; LIHC cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.45e-18 Gut microbiome composition (summer); LIHC cis rs7511006 1.000 rs5771109 chr22:50678571 T/C cg16473166 chr22:50639996 SELO 0.5 7.34 0.37 1.59e-12 Obesity-related traits; LIHC cis rs6456156 0.586 rs720325 chr6:167467349 G/T cg07741184 chr6:167504864 NA 0.3 6.99 0.35 1.45e-11 Primary biliary cholangitis; LIHC cis rs4555082 0.834 rs2735826 chr14:105710866 G/A cg13114125 chr14:105738426 BRF1 -0.78 -10.1 -0.48 3.66e-21 Mean platelet volume;Platelet distribution width; LIHC trans rs1005277 0.522 rs7072977 chr10:37940440 C/A cg23533926 chr12:111358616 MYL2 -0.33 -6.51 -0.33 2.71e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7116495 0.786 rs10736784 chr11:71718911 T/A cg26138937 chr11:71823887 C11orf51 -0.81 -8.15 -0.4 6.86e-15 Severe influenza A (H1N1) infection; LIHC cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg13395646 chr4:1353034 KIAA1530 -0.61 -9.06 -0.44 1.06e-17 Obesity-related traits; LIHC cis rs826838 0.967 rs11169142 chr12:39085773 A/T cg13010199 chr12:38710504 ALG10B -0.4 -6.0 -0.31 5.11e-9 Heart rate; LIHC cis rs1256061 0.624 rs944046 chr14:64700299 G/A cg23250157 chr14:64679961 SYNE2 0.4 5.9 0.3 8.74e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs2066819 1.000 rs78149779 chr12:56694817 A/G cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs17253792 0.822 rs10147380 chr14:56054354 T/C cg01858014 chr14:56050164 KTN1 -0.74 -8.25 -0.41 3.55e-15 Putamen volume; LIHC cis rs2933343 0.601 rs1680758 chr3:128594897 T/C cg25356066 chr3:128598488 ACAD9 0.55 7.66 0.38 1.9e-13 IgG glycosylation; LIHC cis rs16854884 0.632 rs10513234 chr3:143670957 A/G cg06585982 chr3:143692056 C3orf58 -0.6 -8.02 -0.4 1.66e-14 Economic and political preferences (feminism/equality); LIHC cis rs875971 0.964 rs1643388 chr7:65844562 T/C cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs73206853 0.563 rs16940992 chr12:111207515 C/T cg12870014 chr12:110450643 ANKRD13A -0.61 -7.11 -0.36 6.99e-12 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs11190604 1.000 rs2495745 chr10:102329075 A/G cg07080220 chr10:102295463 HIF1AN 0.48 6.57 0.33 1.86e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg03806693 chr22:41940476 POLR3H -1.11 -13.22 -0.58 1.69e-32 Vitiligo; LIHC cis rs9649213 0.593 rs1468338 chr7:97951118 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs9303401 0.659 rs12935851 chr17:56600244 C/A cg25039879 chr17:56429692 SUPT4H1 0.75 8.37 0.41 1.55e-15 Cognitive test performance; LIHC cis rs1018836 0.851 rs10808620 chr8:91622940 T/C cg16814680 chr8:91681699 NA -0.61 -9.77 -0.47 4.81e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs739401 0.611 rs2071104 chr11:3036933 G/T cg08508325 chr11:3079039 CARS -0.32 -6.88 -0.35 2.86e-11 Longevity; LIHC cis rs600806 0.778 rs10745357 chr1:110001876 G/C cg16275483 chr1:110013120 SYPL2 -0.52 -6.54 -0.33 2.19e-10 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg11644478 chr21:40555479 PSMG1 0.79 9.9 0.47 1.7e-20 Cognitive function; LIHC cis rs9911578 1.000 rs7207693 chr17:57016525 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs10744422 0.858 rs10773627 chr12:123311853 A/G cg07706471 chr12:123319906 HIP1R -0.57 -7.55 -0.38 4.03e-13 Schizophrenia; LIHC cis rs7582720 0.943 rs72936879 chr2:203792628 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21023284 chr11:6624872 ILK;RRP8 -0.43 -6.22 -0.32 1.44e-9 Cognitive function; LIHC cis rs73001065 1.000 rs56255430 chr19:19477877 A/C cg03709012 chr19:19516395 GATAD2A 0.83 6.51 0.33 2.74e-10 LDL cholesterol; LIHC cis rs10861342 1.000 rs11112359 chr12:105471661 C/A cg23923672 chr12:105501055 KIAA1033 0.67 7.86 0.39 5.11e-14 IgG glycosylation; LIHC cis rs7772486 0.875 rs6909827 chr6:146365738 A/G cg23711669 chr6:146136114 FBXO30 0.6 10.63 0.5 5.3e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg12463550 chr7:65579703 CRCP 0.68 7.19 0.36 4.12e-12 Diabetic kidney disease; LIHC cis rs9811920 0.541 rs1016914 chr3:99640121 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs12477438 0.520 rs4851187 chr2:99745860 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.93 -14.85 -0.63 7.4e-39 Chronic sinus infection; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07089783 chr10:31607955 ZEB1;LOC220930 0.49 6.42 0.33 4.56e-10 Lung function (FEV1/FVC); LIHC cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs11088226 1.000 rs11088226 chr21:33925531 C/G cg09050820 chr6:167586206 TCP10L2 0.7 10.66 0.5 4.21e-23 Gastritis; LIHC cis rs9733 0.650 rs9803935 chr1:150552622 T/G cg17724175 chr1:150552817 MCL1 -0.37 -7.45 -0.37 7.83e-13 Tonsillectomy; LIHC cis rs9914988 0.943 rs2043032 chr17:27136692 A/G cg20469991 chr17:27169893 C17orf63 -0.62 -6.48 -0.33 3.27e-10 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs8114671 0.586 rs6087634 chr20:33413809 G/A cg07148914 chr20:33460835 GGT7 0.6 8.88 0.43 3.89e-17 Height; LIHC cis rs7582720 1.000 rs72926796 chr2:203827480 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg10802521 chr3:52805072 NEK4 -0.44 -7.36 -0.37 1.35e-12 Bipolar disorder; LIHC cis rs17401966 1.000 rs12136376 chr1:10296452 C/T cg15208524 chr1:10270712 KIF1B 0.44 6.38 0.33 5.61e-10 Hepatocellular carcinoma; LIHC cis rs28493229 0.786 rs3745213 chr19:41248009 C/T cg21869046 chr19:41225005 ITPKC 0.47 6.08 0.31 3.18e-9 Kawasaki disease; LIHC cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg16434002 chr17:42200994 HDAC5 -0.53 -7.8 -0.39 7.78e-14 Total body bone mineral density; LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg12016809 chr21:47604291 C21orf56 -0.49 -7.64 -0.38 2.18e-13 Testicular germ cell tumor; LIHC cis rs11628318 0.614 rs7155804 chr14:103114945 A/G cg12046867 chr14:103022105 NA 0.48 6.95 0.35 1.89e-11 Platelet count; LIHC cis rs7635838 0.892 rs9870881 chr3:11447082 A/G cg00170343 chr3:11313890 ATG7 0.41 6.41 0.33 4.92e-10 HDL cholesterol; LIHC cis rs2243480 0.901 rs35823062 chr7:65965821 A/G cg18252515 chr7:66147081 NA -1.29 -17.47 -0.69 2.78e-49 Diabetic kidney disease; LIHC cis rs6570726 0.557 rs403956 chr6:145829956 T/C cg05347473 chr6:146136440 FBXO30 0.45 6.73 0.34 7.11e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs11722228 0.549 rs55848383 chr4:10081117 C/A cg26043149 chr18:55253948 FECH 0.96 14.01 0.6 1.46e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs13040088 1.000 rs2295000 chr20:61536938 A/G cg23096297 chr20:61557774 DIDO1 -0.84 -11.36 -0.52 1.34e-25 Menopause (age at onset); LIHC cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg14004847 chr7:1930337 MAD1L1 -0.48 -6.9 -0.35 2.57e-11 Bipolar disorder and schizophrenia; LIHC cis rs1670533 1.000 rs11724371 chr4:1052125 T/C cg27284194 chr4:1044797 NA 0.58 8.51 0.42 5.55e-16 Recombination rate (females); LIHC cis rs733592 0.507 rs10747529 chr12:48473369 G/A cg21466736 chr12:48725269 NA 0.33 5.95 0.31 6.81e-9 Plateletcrit; LIHC cis rs17270561 0.723 rs12213243 chr6:25890108 C/T cg16482183 chr6:26056742 HIST1H1C 0.66 7.91 0.39 3.52e-14 Iron status biomarkers; LIHC cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.4 0.45 8.31e-19 Bipolar disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17246714 chr3:55519186 WNT5A 0.49 6.67 0.34 1.05e-10 Lung function (FEV1/FVC); LIHC cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg05665937 chr4:1216051 CTBP1 0.44 5.81 0.3 1.44e-8 Obesity-related traits; LIHC cis rs7552404 1.000 rs12127402 chr1:76205643 C/A cg22875332 chr1:76189707 ACADM 0.47 6.97 0.35 1.63e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs3796352 1.000 rs71299622 chr3:52917038 G/A cg04865290 chr3:52927548 TMEM110 -0.57 -6.37 -0.33 6.22e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.05e-11 Alzheimer's disease; LIHC cis rs453301 0.571 rs2929453 chr8:9084341 A/G cg06636001 chr8:8085503 FLJ10661 -0.43 -5.86 -0.3 1.07e-8 Joint mobility (Beighton score); LIHC cis rs6545883 0.965 rs7591345 chr2:61729641 T/A cg15711740 chr2:61764176 XPO1 -0.43 -6.1 -0.31 2.91e-9 Tuberculosis; LIHC cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC trans rs61931739 0.500 rs7979769 chr12:34509522 C/T cg26384229 chr12:38710491 ALG10B 0.79 9.79 0.47 4.2e-20 Morning vs. evening chronotype; LIHC cis rs10791097 0.694 rs4459316 chr11:130756176 T/C cg12179176 chr11:130786555 SNX19 0.85 13.94 0.6 2.63e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg05552183 chr6:42928497 GNMT 0.67 9.87 0.47 2.18e-20 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs5769765 0.908 rs9616370 chr22:50306316 A/G cg02269571 chr22:50332266 NA 0.76 10.14 0.48 2.76e-21 Schizophrenia; LIHC cis rs919433 0.783 rs788011 chr2:198230771 A/G cg03934865 chr2:198174659 NA 0.57 8.76 0.43 9.31e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs875971 0.545 rs801199 chr7:66025273 A/G cg26939375 chr7:64535504 NA -0.39 -6.2 -0.32 1.66e-9 Aortic root size; LIHC cis rs2404602 0.716 rs17460201 chr15:76673627 C/T cg23625390 chr15:77176239 SCAPER -0.37 -6.19 -0.32 1.7e-9 Blood metabolite levels; LIHC cis rs10751667 1.000 rs7396366 chr11:986185 C/A cg10932868 chr11:921992 NA 0.36 6.61 0.34 1.52e-10 Alzheimer's disease (late onset); LIHC cis rs7020830 0.898 rs12000309 chr9:37230844 G/A cg14294708 chr9:37120828 ZCCHC7 1.18 26.67 0.82 1.47e-85 Schizophrenia; LIHC cis rs8180040 0.620 rs9875235 chr3:47083621 G/A cg16586182 chr3:47516702 SCAP -0.47 -8.54 -0.42 4.6e-16 Colorectal cancer; LIHC cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg14004847 chr7:1930337 MAD1L1 -0.51 -7.6 -0.38 2.85e-13 Bipolar disorder and schizophrenia; LIHC cis rs60871478 1.000 rs62432252 chr7:802886 C/G cg13844804 chr7:814759 HEATR2 0.43 5.78 0.3 1.71e-8 Cerebrospinal P-tau181p levels; LIHC cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.59 0.38 2.99e-13 Electroencephalogram traits; LIHC trans rs10411161 0.702 rs17835311 chr19:52386781 A/C cg22319618 chr22:45562946 NUP50 -0.62 -8.5 -0.42 6.04e-16 Breast cancer; LIHC cis rs6692209 1 rs6692209 chr1:152506444 C/T cg23254163 chr1:152506842 NA 0.23 5.89 0.3 9.35e-9 Plantar warts; LIHC trans rs6934970 0.929 rs12194950 chr6:113095306 G/C cg09308777 chr6:169852575 NA 0.62 6.16 0.32 2.08e-9 Bipolar disorder (body mass index interaction); LIHC cis rs9649465 0.967 rs768680 chr7:123364127 T/C cg03229431 chr7:123269106 ASB15 -0.37 -8.01 -0.4 1.82e-14 Migraine; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.72 10.7 0.5 3.14e-23 Lymphocyte counts; LIHC cis rs6754311 0.593 rs10186843 chr2:136586958 C/A cg07305463 chr2:136567211 LCT 0.38 7.25 0.36 2.83e-12 Mosquito bite size; LIHC cis rs10463316 0.963 rs10463315 chr5:150745615 T/A cg03212797 chr5:150827313 SLC36A1 -0.4 -6.01 -0.31 4.68e-9 Metabolite levels (Pyroglutamine); LIHC cis rs881375 0.678 rs10985102 chr9:123707497 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.27 0.32 1.11e-9 Rheumatoid arthritis; LIHC cis rs2710642 0.611 rs10172216 chr2:62869546 C/G cg17519650 chr2:63277830 OTX1 0.52 7.52 0.38 4.73e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs804280 0.525 rs1004712 chr8:11622293 C/T cg11123440 chr8:11619852 NA 0.37 6.53 0.33 2.33e-10 Myopia (pathological); LIHC cis rs11098499 0.754 rs10518300 chr4:120249499 G/T cg09307838 chr4:120376055 NA -0.71 -10.94 -0.51 4.45e-24 Corneal astigmatism; LIHC cis rs4665809 0.509 rs62128431 chr2:26398116 C/T cg27170947 chr2:26402098 FAM59B 0.62 6.48 0.33 3.19e-10 Gut microbiome composition (summer); LIHC cis rs2637266 0.655 rs846584 chr10:78495419 G/A cg18941641 chr10:78392320 NA 0.28 6.09 0.31 3.12e-9 Pulmonary function; LIHC cis rs919433 0.617 rs34632716 chr2:198542619 C/T cg00792783 chr2:198669748 PLCL1 -0.43 -6.27 -0.32 1.09e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs5770917 1.000 rs1557503 chr22:51013072 G/A cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.41 -5.95 -0.31 6.48e-9 Narcolepsy; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg12176815 chr19:1979540 CSNK1G2 0.38 6.14 0.32 2.23e-9 Bipolar disorder; LIHC cis rs8017423 0.904 rs11848894 chr14:90723660 C/A cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.18e-41 Mortality in heart failure; LIHC cis rs7582180 0.663 rs1114595 chr2:100960072 T/A cg14675211 chr2:100938903 LONRF2 0.55 8.31 0.41 2.24e-15 Intelligence (multi-trait analysis); LIHC cis rs2072499 0.932 rs3001790 chr1:156165290 T/G cg24450063 chr1:156163899 SLC25A44 1.07 18.28 0.7 1.45e-52 Testicular germ cell tumor; LIHC trans rs877282 0.786 rs11253392 chr10:788768 G/A cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs4727027 0.800 rs12530946 chr7:148887942 A/G cg23583168 chr7:148888333 NA -0.74 -10.78 -0.5 1.59e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC trans rs8073060 0.586 rs4795086 chr17:34042190 G/A cg19694781 chr19:47549865 TMEM160 1.22 13.08 0.58 5.37e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs4891159 1.000 rs4891159 chr18:74101941 A/G cg24786174 chr18:74118243 ZNF516 0.68 12.28 0.55 5.75e-29 Longevity; LIHC trans rs4650994 1.000 rs10798617 chr1:178515806 T/C cg05059571 chr16:84539110 KIAA1609 -0.38 -6.35 -0.32 6.98e-10 HDL cholesterol levels;HDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00794227 chr1:28696966 PHACTR4 0.44 6.33 0.32 7.76e-10 Lung function (FEV1/FVC); LIHC cis rs61041384 0.661 rs7967118 chr12:123571503 C/G cg25930673 chr12:123319894 HIP1R 0.64 5.82 0.3 1.33e-8 Schizophrenia; LIHC cis rs9911578 0.835 rs1476596 chr17:56485358 C/T cg12560992 chr17:57184187 TRIM37 0.91 15.22 0.64 2.61e-40 Intelligence (multi-trait analysis); LIHC cis rs9368481 0.594 rs7768643 chr6:26891919 C/T cg12292205 chr6:26970375 C6orf41 0.43 7.17 0.36 4.55e-12 Autism spectrum disorder or schizophrenia; LIHC trans rs911555 0.755 rs4143998 chr14:103955247 T/C cg17675199 chr6:35436792 RPL10A 0.43 8.89 0.43 3.45e-17 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.752 rs11211147 chr1:46110094 A/G cg03146154 chr1:46216737 IPP 0.56 9.58 0.46 1.99e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1814175 0.645 rs1851850 chr11:50012168 G/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC trans rs1814175 0.817 rs12290508 chr11:49621037 C/T cg03929089 chr4:120376271 NA -0.89 -18.0 -0.7 1.99e-51 Height; LIHC cis rs9902453 0.715 rs2628176 chr17:28139292 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -12.19 -0.55 1.28e-28 Coffee consumption (cups per day); LIHC cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg17554472 chr22:41940697 POLR3H -0.56 -6.11 -0.31 2.77e-9 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04787407 chr4:99916511 METAP1 0.43 6.38 0.33 5.83e-10 Pancreatic cancer; LIHC trans rs3780486 0.629 rs10971439 chr9:33180813 C/T cg20290983 chr6:43655470 MRPS18A -0.8 -11.23 -0.52 4.14e-25 IgG glycosylation; LIHC cis rs780094 0.544 rs780108 chr2:27684957 T/C cg21248554 chr2:27665150 KRTCAP3 -0.43 -5.77 -0.3 1.74e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs2075371 1.000 rs2244700 chr7:133987374 A/G cg20476274 chr7:133979776 SLC35B4 0.73 12.24 0.55 8.44e-29 Mean platelet volume; LIHC cis rs2153535 0.580 rs7747306 chr6:8453663 C/G cg23788917 chr6:8435910 SLC35B3 -0.6 -8.6 -0.42 2.86e-16 Motion sickness; LIHC cis rs9303401 0.659 rs7216648 chr17:56790858 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs4845570 0.920 rs1521185 chr1:151764049 A/G cg07092448 chr1:151763213 TDRKH 0.94 17.03 0.68 1.55e-47 Coronary artery disease; LIHC cis rs3820068 0.705 rs6656907 chr1:15896984 A/G cg17385448 chr1:15911702 AGMAT 0.41 6.85 0.35 3.49e-11 Systolic blood pressure; LIHC cis rs7208859 0.573 rs11656121 chr17:29214043 A/G cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.67 9.77 0.47 4.62e-20 Lymphocyte counts; LIHC cis rs2304069 0.909 rs30831 chr5:149359053 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.96 -12.14 -0.55 1.87e-28 HIV-1 control; LIHC cis rs7520050 0.966 rs6668284 chr1:46354510 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 5.97 0.31 5.8e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg21724239 chr8:58056113 NA 0.57 7.02 0.35 1.22e-11 Developmental language disorder (linguistic errors); LIHC cis rs561341 0.528 rs11650908 chr17:30195425 T/C cg13647721 chr17:30228624 UTP6 -0.67 -7.29 -0.37 2.1e-12 Hip circumference adjusted for BMI; LIHC cis rs2404602 0.647 rs11852395 chr15:77087785 T/C cg23625390 chr15:77176239 SCAPER -0.54 -9.01 -0.44 1.46e-17 Blood metabolite levels; LIHC cis rs7193541 0.684 rs7201320 chr16:74694058 T/G cg01733217 chr16:74700730 RFWD3 0.91 22.92 0.78 4.37e-71 Multiple myeloma; LIHC cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg02187348 chr16:89574699 SPG7 0.53 7.87 0.39 4.62e-14 Multiple myeloma (IgH translocation); LIHC cis rs6570726 0.526 rs9376934 chr6:145738702 A/G cg23711669 chr6:146136114 FBXO30 0.4 6.47 0.33 3.45e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05949034 chr4:83295361 HNRNPD -0.58 -7.11 -0.36 6.85e-12 Systolic blood pressure; LIHC cis rs7520050 0.778 rs3014238 chr1:46090214 A/G cg03146154 chr1:46216737 IPP -0.46 -7.75 -0.39 1.09e-13 Red blood cell count;Reticulocyte count; LIHC cis rs7267979 0.934 rs2257464 chr20:25265872 C/T cg24626310 chr20:25276739 ABHD12;PYGB 0.44 6.47 0.33 3.48e-10 Liver enzyme levels (alkaline phosphatase); LIHC cis rs8062405 0.755 rs4788078 chr16:28559981 G/A cg07382826 chr16:28625726 SULT1A1 0.49 7.68 0.38 1.74e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs67311347 0.955 rs6773383 chr3:40377412 A/T cg16822855 chr3:40428330 ENTPD3 0.32 5.89 0.3 9.28e-9 Renal cell carcinoma; LIHC cis rs17401966 1.000 rs12129035 chr1:10291166 G/A cg19773385 chr1:10388646 KIF1B -0.47 -8.19 -0.41 5.14e-15 Hepatocellular carcinoma; LIHC cis rs2066819 0.901 rs773665 chr12:56717466 C/T cg26734620 chr12:56694298 CS -1.02 -10.33 -0.49 5.91e-22 Psoriasis vulgaris; LIHC trans rs2352908 1.000 rs6572530 chr14:49446168 C/T cg16568472 chr20:3190600 ITPA -0.45 -6.13 -0.31 2.41e-9 Social communication problems; LIHC cis rs422249 0.512 rs99780 chr11:61596633 C/T cg27386326 chr11:61587980 NA 0.71 15.37 0.64 6.9e-41 Trans fatty acid levels; LIHC cis rs12477438 0.765 rs2278895 chr2:99613484 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.59 -0.5 7.31e-23 Chronic sinus infection; LIHC cis rs7666738 0.830 rs28761309 chr4:98867393 C/T cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs2404602 0.647 rs36114653 chr15:77025393 G/A cg03037974 chr15:76606532 NA -0.58 -9.57 -0.46 2.14e-19 Blood metabolite levels; LIHC cis rs1577917 1.000 rs12205336 chr6:86722367 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -9.97 -0.47 1e-20 Response to antipsychotic treatment; LIHC cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg16145915 chr7:1198662 ZFAND2A -0.33 -8.23 -0.41 4.08e-15 Longevity;Endometriosis; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg01516881 chr6:292596 DUSP22 -0.52 -6.79 -0.34 5.03e-11 Menopause (age at onset); LIHC cis rs6912958 0.874 rs2103764 chr6:88157392 T/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.4 -7.15 -0.36 5.35e-12 Monocyte percentage of white cells; LIHC cis rs4853012 0.838 rs4563249 chr2:74354016 G/T cg05890377 chr2:74357713 NA 0.62 12.91 0.57 2.47e-31 Gestational age at birth (maternal effect); LIHC cis rs9443189 0.570 rs529383 chr6:76297847 T/G cg01950844 chr6:76311363 SENP6 0.9 10.53 0.49 1.23e-22 Prostate cancer; LIHC cis rs765787 0.530 rs55920042 chr15:45541577 G/A cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC cis rs7312774 0.618 rs726943 chr12:107331647 A/G cg16260113 chr12:107380972 MTERFD3 0.84 11.09 0.51 1.28e-24 Severe influenza A (H1N1) infection; LIHC cis rs249954 0.512 rs703769 chr16:23654509 T/G cg05131483 chr16:23706242 ERN2 0.37 5.94 0.31 7.05e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs1814175 0.588 rs4076322 chr11:49745094 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.94 0.35 1.94e-11 Height; LIHC cis rs637571 0.607 rs575479 chr11:65690300 T/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 8.56 0.42 3.8e-16 Eosinophil percentage of white cells; LIHC cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg04267008 chr7:1944627 MAD1L1 -0.68 -10.81 -0.5 1.3e-23 Bipolar disorder and schizophrenia; LIHC cis rs9905704 0.647 rs8077332 chr17:57105223 A/G cg12560992 chr17:57184187 TRIM37 0.67 9.82 0.47 3.33e-20 Testicular germ cell tumor; LIHC cis rs1799949 0.930 rs34210004 chr17:41370337 A/T cg25072359 chr17:41440525 NA 0.38 6.04 0.31 4.09e-9 Menopause (age at onset); LIHC cis rs317689 0.684 rs315125 chr12:69758884 C/T cg14784868 chr12:69753453 YEATS4 0.67 10.22 0.48 1.45e-21 Response to diuretic therapy; LIHC cis rs2569991 0.891 rs361224 chr3:12922313 C/T cg07263372 chr3:12940286 IQSEC1 -0.34 -5.75 -0.3 2.03e-8 Periodontitis (DPAL); LIHC cis rs4927850 0.752 rs7618864 chr3:195749561 G/A cg00031303 chr3:195681400 NA 0.32 5.78 0.3 1.65e-8 Pancreatic cancer; LIHC cis rs8064299 0.597 rs6501736 chr17:72775358 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.83 14.96 0.63 2.72e-39 Monocyte count; LIHC trans rs2243480 0.901 rs73142137 chr7:65343442 A/T cg10756647 chr7:56101905 PSPH 1.11 13.27 0.58 1.06e-32 Diabetic kidney disease; LIHC cis rs2839186 0.559 rs2277826 chr21:47639492 C/G cg09417038 chr21:47716443 C21orf57 0.55 8.37 0.41 1.45e-15 Testicular germ cell tumor; LIHC cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.8e-13 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg23262073 chr20:60523788 NA -0.29 -5.94 -0.31 6.89e-9 Body mass index; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg01171360 chr6:293285 DUSP22 -0.47 -6.82 -0.35 4.08e-11 Menopause (age at onset); LIHC cis rs3849570 0.925 rs6798680 chr3:81905441 C/A cg07356753 chr3:81810745 GBE1 -0.55 -8.63 -0.42 2.28e-16 Waist circumference;Body mass index; LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg24209194 chr3:40518798 ZNF619 0.64 9.67 0.46 1.06e-19 Renal cell carcinoma; LIHC cis rs10744422 1.000 rs936083 chr12:123338964 A/G cg22842854 chr12:123319900 HIP1R -0.74 -9.83 -0.47 2.99e-20 Schizophrenia; LIHC cis rs78545713 0.536 rs78653353 chr6:26208917 A/G cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC trans rs1814175 0.669 rs12416837 chr11:49669761 G/T cg03929089 chr4:120376271 NA -0.53 -8.92 -0.43 2.95e-17 Height; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs11673344 0.864 rs7256213 chr19:37511491 T/C cg27390819 chr19:37464633 NA -0.51 -6.21 -0.32 1.57e-9 Obesity-related traits; LIHC cis rs4561483 0.801 rs4511557 chr16:11949458 T/C cg08843971 chr16:11963173 GSPT1 0.42 8.19 0.41 5.14e-15 Testicular germ cell tumor; LIHC trans rs7613875 0.578 rs2624822 chr3:50107219 T/C cg21659725 chr3:3221576 CRBN -0.55 -8.16 -0.4 6.51e-15 Body mass index; LIHC trans rs7618501 0.699 rs11130224 chr3:49936910 T/A cg21659725 chr3:3221576 CRBN 0.68 10.57 0.5 8.75e-23 Intelligence (multi-trait analysis); LIHC cis rs9549367 0.789 rs9549705 chr13:113888425 T/C cg00898013 chr13:113819073 PROZ -0.42 -7.34 -0.37 1.6e-12 Platelet distribution width; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg27417846 chr2:88927289 EIF2AK3 -0.39 -6.06 -0.31 3.63e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2274273 0.905 rs2075601 chr14:55609234 C/T cg04306507 chr14:55594613 LGALS3 0.33 6.37 0.33 6.21e-10 Protein biomarker; LIHC cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg02951883 chr7:2050386 MAD1L1 -0.77 -13.32 -0.58 6.54e-33 Bipolar disorder and schizophrenia; LIHC cis rs4834770 1.000 rs1397613 chr4:120242929 G/T cg09307838 chr4:120376055 NA 0.43 6.5 0.33 2.87e-10 Blood protein levels; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg13752114 chr3:195489708 MUC4 -0.7 -11.47 -0.53 5.26e-26 Lung disease severity in cystic fibrosis; LIHC cis rs2710642 0.611 rs1843779 chr2:62866762 T/C cg17519650 chr2:63277830 OTX1 0.47 6.88 0.35 2.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs9818758 0.607 rs9862483 chr3:49195441 G/A cg00383909 chr3:49044727 WDR6 0.79 6.82 0.35 4.05e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7737355 0.898 rs32109 chr5:131041590 C/T cg06307176 chr5:131281290 NA 0.39 5.72 0.3 2.35e-8 Life satisfaction; LIHC cis rs3768617 0.510 rs2027083 chr1:183088330 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC trans rs916888 0.821 rs199499 chr17:44865498 C/T cg22968622 chr17:43663579 NA 1.24 11.45 0.53 6.4e-26 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs12493885 0.725 rs4680113 chr3:153727337 C/T cg10247383 chr3:153839028 SGEF 0.65 5.97 0.31 5.93e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs933688 1.000 rs1895448 chr5:90743854 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.85 17.9 0.7 4.78e-51 Smoking behavior; LIHC cis rs918629 0.563 rs3777188 chr5:95254502 A/G cg10483112 chr5:95245456 ELL2 -0.35 -6.48 -0.33 3.12e-10 IgG glycosylation; LIHC cis rs950776 0.518 rs12915428 chr15:78823368 G/A cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs7582720 0.806 rs72926770 chr2:203798585 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs950169 0.922 rs11633534 chr15:85124642 C/T cg12863693 chr15:85201151 NMB 0.44 6.02 0.31 4.62e-9 Schizophrenia; LIHC cis rs9381040 0.610 rs2268191 chr6:41027653 G/C cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.77 -0.3 1.82e-8 Alzheimer's disease (late onset); LIHC cis rs9916302 0.555 rs12940193 chr17:37652178 T/G cg07936489 chr17:37558343 FBXL20 -0.84 -13.6 -0.59 5.55e-34 Glomerular filtration rate (creatinine); LIHC cis rs55665837 1.000 rs10832254 chr11:14434698 A/G cg19336497 chr11:14380999 RRAS2 -0.46 -8.5 -0.42 5.91e-16 Vitamin D levels; LIHC cis rs1448094 0.512 rs12314274 chr12:86249196 A/G cg02569458 chr12:86230093 RASSF9 0.47 6.31 0.32 8.77e-10 Major depressive disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24631450 chr2:234262952 DGKD 0.45 6.22 0.32 1.47e-9 Lung function (FEV1/FVC); LIHC cis rs7647973 1.000 rs9871024 chr3:49554241 T/C cg07636037 chr3:49044803 WDR6 -0.54 -6.65 -0.34 1.18e-10 Menarche (age at onset); LIHC cis rs6442522 0.809 rs12494163 chr3:15423834 A/G cg16303742 chr3:15540471 COLQ 0.37 6.04 0.31 4.09e-9 Uric acid levels; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg12648201 chr2:27665141 KRTCAP3 -0.42 -5.82 -0.3 1.34e-8 Total body bone mineral density; LIHC cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.57 -9.67 -0.46 1.07e-19 Bipolar disorder; LIHC cis rs1005277 1.000 rs1005277 chr10:38218259 A/C cg25427524 chr10:38739819 LOC399744 0.4 6.32 0.32 8.31e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.22 -0.32 1.49e-9 Diastolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04844971 chr15:50979486 TRPM7 0.48 7.71 0.38 1.38e-13 Cognitive function; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14992232 chr1:20811153 CAMK2N1 0.41 6.08 0.31 3.18e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01809819 chr1:31192165 MATN1 0.45 6.86 0.35 3.19e-11 Pancreatic cancer; LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg12516959 chr21:47718080 NA -0.36 -5.8 -0.3 1.48e-8 Testicular germ cell tumor; LIHC cis rs2050392 0.517 rs2771242 chr10:30762973 C/T cg25182066 chr10:30743637 MAP3K8 -0.68 -11.27 -0.52 2.86e-25 Inflammatory bowel disease; LIHC cis rs7903847 0.642 rs2275090 chr10:99148151 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9527 0.615 rs10883800 chr10:104671212 A/C cg15744005 chr10:104629667 AS3MT -0.29 -5.81 -0.3 1.41e-8 Arsenic metabolism; LIHC cis rs13108904 0.846 rs3775100 chr4:1225106 T/C cg02980000 chr4:1222292 CTBP1 -0.55 -7.9 -0.39 3.77e-14 Obesity-related traits; LIHC cis rs9816226 1.000 rs55835921 chr3:185831474 T/C cg00760338 chr3:185826511 ETV5 -0.71 -6.47 -0.33 3.42e-10 Obesity;Body mass index; LIHC cis rs7937890 1.000 rs7937890 chr11:14396485 C/T cg22961513 chr11:14280813 SPON1 -0.46 -7.24 -0.36 3e-12 Mitochondrial DNA levels; LIHC cis rs7534824 0.625 rs6686202 chr1:101493078 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.73 7.28 0.37 2.36e-12 Refractive astigmatism; LIHC cis rs7027203 0.828 rs7037960 chr9:96584028 G/A cg14396892 chr9:96623032 NA -0.31 -6.14 -0.32 2.23e-9 DNA methylation (variation); LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg24693881 chr1:107596107 NA -0.54 -9.39 -0.45 8.42e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10504229 1.000 rs76944716 chr8:58191643 T/C cg02290350 chr8:58132656 NA 0.39 7.6 0.38 2.95e-13 Developmental language disorder (linguistic errors); LIHC cis rs7149337 0.809 rs10134478 chr14:51693708 G/C cg23942311 chr14:51606299 NA 0.32 6.17 0.32 1.9e-9 Cancer; LIHC cis rs3862260 0.509 rs3862262 chr1:120161841 G/T cg11530693 chr1:120165357 ZNF697 0.48 7.47 0.37 6.75e-13 Systemic lupus erythematosus; LIHC cis rs6500602 0.767 rs8060219 chr16:4480158 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.45 0.33 3.82e-10 Schizophrenia; LIHC cis rs12586317 0.547 rs28589276 chr14:35478865 A/G cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.03e-32 Psoriasis; LIHC cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg24101359 chr6:42928495 GNMT 0.43 5.89 0.3 9.26e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.13 -0.31 2.48e-9 Total body bone mineral density; LIHC cis rs4555082 0.874 rs11625098 chr14:105756891 A/G cg10792982 chr14:105748885 BRF1 0.48 6.23 0.32 1.4e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs734999 0.550 rs2985855 chr1:2531372 A/C cg18854424 chr1:2615690 NA -0.33 -7.25 -0.36 2.82e-12 Ulcerative colitis; LIHC trans rs7395662 0.517 rs11039885 chr11:48647107 A/G cg03929089 chr4:120376271 NA -0.41 -6.3 -0.32 9.11e-10 HDL cholesterol; LIHC cis rs765787 0.530 rs1631533 chr15:45518628 C/T cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.75e-10 Uric acid levels; LIHC cis rs9733 0.596 rs2867300 chr1:150666990 C/G cg17724175 chr1:150552817 MCL1 0.48 9.63 0.46 1.44e-19 Tonsillectomy; LIHC cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.46 6.16 0.32 2.06e-9 Bipolar disorder; LIHC cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg21226059 chr5:178986404 RUFY1 -0.37 -5.71 -0.3 2.44e-8 Lung cancer; LIHC trans rs208515 0.525 rs10455593 chr6:66691341 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.86 0.43 4.37e-17 Exhaled nitric oxide levels; LIHC cis rs9303401 1.000 rs7218362 chr17:56888299 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.43 6.39 0.33 5.3e-10 Cognitive test performance; LIHC cis rs10744422 1.000 rs7138398 chr12:123341833 G/C cg25930673 chr12:123319894 HIP1R -0.95 -12.64 -0.56 2.48e-30 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24084363 chr13:45992551 SLC25A30 0.42 6.05 0.31 3.84e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18850918 chr19:18633063 ELL 0.4 6.03 0.31 4.14e-9 Cognitive function; LIHC cis rs6748734 1.000 rs4293565 chr2:241834770 A/G cg20140201 chr2:241835670 C2orf54 -0.47 -6.47 -0.33 3.31e-10 Urinary metabolites; LIHC cis rs7703051 0.513 rs59014134 chr5:74589385 C/T cg00601450 chr5:74908170 NA 0.48 6.47 0.33 3.31e-10 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs10911251 0.546 rs1051473 chr1:183114146 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.66 0.5 4.1000000000000003e-23 Colorectal cancer; LIHC cis rs7224685 0.569 rs2123841 chr17:4022557 G/C cg11204139 chr17:3907470 NA 0.59 6.89 0.35 2.72e-11 Type 2 diabetes; LIHC cis rs57143961 1 rs57143961 chr19:16533225 C/CT cg10248733 chr19:16607483 C19orf44;CALR3 -0.73 -8.31 -0.41 2.21e-15 Lymphocyte percentage of white cells; LIHC cis rs7927771 0.896 rs12794570 chr11:47658314 C/T cg20307385 chr11:47447363 PSMC3 -0.45 -5.88 -0.3 9.64e-9 Subjective well-being; LIHC cis rs4631830 0.683 rs11004409 chr10:51498019 G/C cg20129853 chr10:51489980 NA 0.4 8.57 0.42 3.7e-16 Prostate-specific antigen levels; LIHC cis rs4716602 0.596 rs4490714 chr7:156162510 C/A cg16983916 chr7:156159713 NA -0.34 -5.95 -0.31 6.58e-9 Anti-saccade response; LIHC cis rs35110281 0.805 rs2838319 chr21:44991901 A/G cg21573476 chr21:45109991 RRP1B -0.54 -10.29 -0.49 8.03e-22 Mean corpuscular volume; LIHC cis rs11105298 0.891 rs10506972 chr12:89861529 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.54 -0.38 4.24e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs62103177 0.564 rs2115996 chr18:77701007 C/G cg05926928 chr17:57297772 GDPD1 0.82 9.3 0.45 1.69e-18 Opioid sensitivity; LIHC cis rs7937682 0.924 rs6589244 chr11:111534333 T/C cg09085632 chr11:111637200 PPP2R1B -1.06 -13.52 -0.59 1.14e-33 Primary sclerosing cholangitis; LIHC cis rs2380220 0.606 rs4559095 chr6:95994154 A/C cg04719120 chr6:96025338 MANEA 0.49 6.06 0.31 3.63e-9 Behavioural disinhibition (generation interaction); LIHC cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg25897951 chr4:1244024 CTBP1;C4orf42 0.4 5.89 0.3 9.18e-9 Longevity; LIHC cis rs9457247 0.765 rs9459838 chr6:167426599 C/G cg23791538 chr6:167370224 RNASET2 -0.51 -7.9 -0.39 3.74e-14 Crohn's disease; LIHC cis rs8067354 0.574 rs7219089 chr17:58032865 C/T cg02344993 chr17:57696989 CLTC 0.65 10.28 0.49 8.95e-22 Hemoglobin concentration; LIHC cis rs6840360 0.571 rs17275536 chr4:152498625 C/T cg22705602 chr4:152727874 NA -0.33 -6.49 -0.33 3.05e-10 Intelligence (multi-trait analysis); LIHC cis rs9918079 0.506 rs10214 chr4:15606431 T/C cg21123203 chr4:15471301 CC2D2A 0.47 7.57 0.38 3.41e-13 Obesity-related traits; LIHC cis rs9596863 1.000 rs7995218 chr13:54427874 C/G ch.13.53330881F chr13:54432880 NA 0.45 5.88 0.3 9.55e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs11039798 0.582 rs1483119 chr11:48382334 A/G cg15704280 chr7:45808275 SEPT13 -0.57 -6.35 -0.32 6.83e-10 Axial length; LIHC cis rs1355223 0.902 rs1539251 chr11:34742772 A/G cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg27286337 chr10:134555280 INPP5A 0.94 13.39 0.59 3.54e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17125944 0.505 rs77690283 chr14:53233320 C/G cg00686598 chr14:53173677 PSMC6 1.2 15.24 0.64 2.21e-40 Alzheimer's disease (late onset); LIHC cis rs2075371 1.000 rs2598294 chr7:133991690 C/T cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC cis rs921968 0.541 rs6710383 chr2:219359685 T/G cg02176678 chr2:219576539 TTLL4 0.52 7.09 0.36 7.61e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs67460515 0.567 rs34691229 chr3:160876897 G/T cg03342759 chr3:160939853 NMD3 -0.65 -9.79 -0.47 4.25e-20 Parkinson's disease; LIHC cis rs11958404 0.517 rs35714701 chr5:157302862 T/C cg05962755 chr5:157440814 NA 0.76 7.35 0.37 1.51e-12 IgG glycosylation; LIHC cis rs17401966 0.928 rs11121531 chr1:10277357 G/A cg19773385 chr1:10388646 KIF1B -0.47 -8.03 -0.4 1.58e-14 Hepatocellular carcinoma; LIHC cis rs9911578 0.805 rs1811202 chr17:56454435 T/G cg12560992 chr17:57184187 TRIM37 -0.83 -12.64 -0.56 2.6e-30 Intelligence (multi-trait analysis); LIHC cis rs59698941 0.825 rs4705974 chr5:132198942 C/T cg02081065 chr5:132209139 LEAP2 0.27 6.11 0.31 2.69e-9 Apolipoprotein A-IV levels; LIHC cis rs6951245 0.529 rs10262070 chr7:1141738 C/T cg22907277 chr7:1156413 C7orf50 0.85 8.06 0.4 1.32e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9733 0.596 rs11204687 chr1:150629880 C/A cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs644799 0.511 rs1016030 chr11:95472693 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.54 6.89 0.35 2.62e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7503168 1.000 rs7503168 chr17:33885904 A/G cg20932281 chr17:33905541 PEX12 0.57 7.34 0.37 1.6e-12 Plateletcrit; LIHC cis rs2075371 0.933 rs2244548 chr7:133986234 A/G cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC cis rs6867032 1.000 rs4975794 chr5:2015330 A/G cg26168224 chr5:2018326 NA -0.32 -8.06 -0.4 1.32e-14 Gut microbiome composition (winter); LIHC cis rs4742903 0.935 rs1450681 chr9:106932435 A/G cg14250997 chr9:106856677 SMC2 0.35 5.93 0.31 7.38e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs12142240 0.698 rs17361763 chr1:46810670 T/C cg00530320 chr1:46809349 NSUN4 0.54 5.8 0.3 1.48e-8 Menopause (age at onset); LIHC cis rs1691799 0.899 rs1168325 chr12:66728234 C/G cg16791601 chr12:66731901 HELB -0.56 -13.8 -0.6 9.24e-35 White blood cell count (basophil); LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg17178900 chr1:205818956 PM20D1 0.65 9.88 0.47 1.98e-20 Menarche (age at onset); LIHC cis rs12594515 1.000 rs8039974 chr15:45986665 A/G cg19682013 chr15:45996608 NA 0.4 6.9 0.35 2.58e-11 Waist circumference;Weight; LIHC cis rs10911232 0.507 rs10911234 chr1:183053001 A/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Hypertriglyceridemia; LIHC cis rs7520050 0.966 rs6675946 chr1:46371774 G/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.73 0.3 2.16e-8 Red blood cell count;Reticulocyte count; LIHC cis rs4908768 0.539 rs1381928 chr1:8690933 G/A cg20416874 chr1:8611966 RERE -0.64 -12.53 -0.56 6.67e-30 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg11494091 chr17:61959527 GH2 0.44 8.19 0.4 5.24e-15 Prudent dietary pattern; LIHC cis rs9399135 0.967 rs9389253 chr6:135329755 T/C cg22676075 chr6:135203613 NA 0.39 6.33 0.32 7.87e-10 Red blood cell count; LIHC cis rs11792861 0.781 rs11789252 chr9:111762010 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 8.92 0.43 2.83e-17 Menarche (age at onset); LIHC cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg13944838 chr5:179740914 GFPT2 -0.49 -6.96 -0.35 1.7e-11 Height; LIHC cis rs7772486 0.875 rs10457794 chr6:146415608 A/G cg05347473 chr6:146136440 FBXO30 0.38 5.95 0.31 6.67e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6684514 1.000 rs12027741 chr1:156248148 T/G cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7264396 0.790 rs6058288 chr20:34228680 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.57 8.67 0.42 1.78e-16 Total cholesterol levels; LIHC cis rs11229555 0.645 rs12800531 chr11:58180099 C/T cg15696309 chr11:58395628 NA -0.66 -7.76 -0.39 1.02e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs3749237 0.595 rs11130192 chr3:49467206 C/G cg07636037 chr3:49044803 WDR6 0.56 8.5 0.42 5.79e-16 Resting heart rate; LIHC trans rs1147813 0.654 rs993232 chr9:25890597 A/G cg02038173 chr21:34852701 TMEM50B 0.48 6.06 0.31 3.66e-9 Morning vs. evening chronotype; LIHC cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg20090690 chr10:134436459 INPP5A 0.42 5.89 0.3 9.36e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1023500 0.573 rs13057094 chr22:42470317 T/C cg04733989 chr22:42467013 NAGA 0.66 9.34 0.45 1.28e-18 Schizophrenia; LIHC cis rs6570726 0.577 rs399502 chr6:145805874 A/G cg05347473 chr6:146136440 FBXO30 0.45 6.19 0.32 1.69e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11758351 1.000 rs11755210 chr6:26202768 C/T cg16070018 chr6:26224392 HIST1H3E 0.56 6.67 0.34 1.06e-10 Gout;Renal underexcretion gout; LIHC cis rs9457247 0.967 rs387733 chr6:167409771 C/T cg12798992 chr6:167411361 FGFR1OP -0.63 -10.35 -0.49 5.09e-22 Crohn's disease; LIHC cis rs7208859 0.573 rs7223803 chr17:29077193 A/G cg14067834 chr17:29058358 SUZ12P 0.68 6.69 0.34 9.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9318086 0.624 rs9510909 chr13:24436760 C/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.57 11.26 0.52 3.14e-25 Myopia (pathological); LIHC cis rs7584330 0.518 rs7561919 chr2:238435241 A/G cg08992911 chr2:238395768 MLPH 0.54 6.03 0.31 4.14e-9 Prostate cancer; LIHC cis rs589448 0.900 rs588493 chr12:69751986 G/A cg20891283 chr12:69753455 YEATS4 0.96 22.23 0.77 2.2e-68 Cerebrospinal fluid biomarker levels; LIHC cis rs7684446 1 rs7684446 chr4:15592864 C/T cg21329975 chr4:15471214 CC2D2A 0.37 5.96 0.31 6.35e-9 Red blood cell count; LIHC cis rs7903847 0.642 rs11812223 chr10:99158455 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.54 -0.33 2.31e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs611744 0.967 rs610452 chr8:109188263 T/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs2727020 0.554 rs2866490 chr11:49425463 A/G cg03929089 chr4:120376271 NA -0.67 -9.86 -0.47 2.44e-20 Coronary artery disease; LIHC cis rs2404602 0.646 rs3764245 chr15:77223176 G/C cg23625390 chr15:77176239 SCAPER 0.51 8.68 0.42 1.69e-16 Blood metabolite levels; LIHC cis rs7106204 0.686 rs12803558 chr11:24288205 C/A ch.11.24196551F chr11:24239977 NA 0.69 6.42 0.33 4.64e-10 Response to Homoharringtonine (cytotoxicity); LIHC cis rs9420 0.890 rs547891 chr11:57499065 C/T cg19752551 chr11:57585705 CTNND1 0.51 7.25 0.37 2.72e-12 Schizophrenia; LIHC trans rs61931739 0.500 rs7295779 chr12:34460652 T/C cg26384229 chr12:38710491 ALG10B 0.63 8.15 0.4 6.95e-15 Morning vs. evening chronotype; LIHC cis rs7552404 0.690 rs2029681 chr1:76333846 G/A cg10523679 chr1:76189770 ACADM -0.55 -6.65 -0.34 1.17e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6089829 1.000 rs6089829 chr20:61669036 C/T cg08564027 chr20:61660810 NA -0.37 -7.02 -0.36 1.17e-11 Prostate cancer (SNP x SNP interaction); LIHC cis rs4900538 0.963 rs4906205 chr14:102932447 A/G cg18135206 chr14:102964638 TECPR2 0.91 15.63 0.65 5.94e-42 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs950776 0.518 rs952216 chr15:78819202 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.6 0.34 1.56e-10 Sudden cardiac arrest; LIHC cis rs4319547 0.695 rs10846746 chr12:122868696 C/T cg05707623 chr12:122985044 ZCCHC8 0.54 7.19 0.36 3.98e-12 Body mass index; LIHC cis rs1113500 0.862 rs2336129 chr1:108640669 A/G cg06207961 chr1:108661230 NA -0.38 -7.59 -0.38 3.09e-13 Growth-regulated protein alpha levels; LIHC cis rs7487075 0.619 rs10880970 chr12:46830420 A/G cg23829395 chr12:46796953 NA 0.34 6.05 0.31 3.81e-9 Itch intensity from mosquito bite; LIHC cis rs1862618 0.641 rs252893 chr5:56224714 T/C cg24531977 chr5:56204891 C5orf35 -0.54 -7.83 -0.39 6.27e-14 Initial pursuit acceleration; LIHC cis rs7843479 0.601 rs11135764 chr8:21814004 A/G cg17168535 chr8:21777572 XPO7 0.59 10.31 0.49 6.87e-22 Mean corpuscular volume; LIHC cis rs11718455 0.585 rs17076170 chr3:43917946 C/T cg08738300 chr3:44038990 NA 0.36 6.27 0.32 1.08e-9 Coronary artery disease; LIHC cis rs4927850 0.521 rs4927679 chr3:195658360 C/T cg20384732 chr3:195601375 TNK2 0.36 5.73 0.3 2.21e-8 Pancreatic cancer; LIHC cis rs2302190 1.000 rs8065388 chr17:56562132 C/T cg12560992 chr17:57184187 TRIM37 0.71 9.19 0.45 3.87e-18 Vitamin D levels; LIHC cis rs7116495 0.881 rs7128974 chr11:71677032 C/G cg26138937 chr11:71823887 C11orf51 0.83 8.19 0.41 5.11e-15 Severe influenza A (H1N1) infection; LIHC trans rs1814175 0.712 rs9665784 chr11:50030617 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC cis rs1799949 0.965 rs799908 chr17:41278916 A/G cg23758822 chr17:41437982 NA 0.91 16.8 0.67 1.33e-46 Menopause (age at onset); LIHC cis rs875971 0.545 rs2460427 chr7:65619205 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.37 -7.37 -0.37 1.28e-12 Aortic root size; LIHC cis rs4819052 0.851 rs2255774 chr21:46683851 A/T cg22633049 chr21:46681294 NA -0.42 -7.56 -0.38 3.85e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18712231 chr3:57903821 SLMAP -0.29 -6.76 -0.34 5.88e-11 Calcium levels; LIHC cis rs2404602 0.735 rs4886798 chr15:76673226 A/G cg23625390 chr15:77176239 SCAPER 0.48 8.02 0.4 1.66e-14 Blood metabolite levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11490961 chr3:123418713 MYLK 0.39 6.53 0.33 2.38e-10 Bilirubin levels; LIHC cis rs7772486 0.875 rs9322043 chr6:146352690 A/G cg23711669 chr6:146136114 FBXO30 0.67 11.79 0.54 3.82e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs1385374 1.000 rs12311303 chr12:129301592 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.61 7.52 0.38 4.97e-13 Systemic lupus erythematosus; LIHC cis rs8180040 0.726 rs10461018 chr3:46995242 C/T cg02527881 chr3:46936655 PTH1R 0.31 6.08 0.31 3.23e-9 Colorectal cancer; LIHC cis rs1005277 0.579 rs2474572 chr10:38385316 A/G cg25427524 chr10:38739819 LOC399744 -0.68 -13.35 -0.59 5.14e-33 Extrinsic epigenetic age acceleration; LIHC cis rs17685 0.712 rs56965035 chr7:75795670 G/A cg04610667 chr7:75704037 NA -0.35 -6.21 -0.32 1.54e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs853679 0.517 rs9380059 chr6:28132358 A/C cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs826838 0.967 rs826858 chr12:39116731 A/G cg13010199 chr12:38710504 ALG10B -0.42 -6.03 -0.31 4.25e-9 Heart rate; LIHC cis rs9911578 0.935 rs9911753 chr17:56983174 G/A cg05425664 chr17:57184151 TRIM37 -0.55 -8.3 -0.41 2.36e-15 Intelligence (multi-trait analysis); LIHC cis rs3106136 0.843 rs4282187 chr4:95273145 T/C cg11021082 chr4:95130006 SMARCAD1 0.42 7.27 0.37 2.44e-12 Capecitabine sensitivity; LIHC cis rs798554 0.610 rs2644297 chr7:2858906 A/C cg19717773 chr7:2847554 GNA12 -0.42 -7.46 -0.37 7.4e-13 Height; LIHC cis rs6684514 1.000 rs12117903 chr1:156311165 G/T cg16558208 chr1:156270281 VHLL 0.54 10.33 0.49 5.84e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg20295408 chr7:1910781 MAD1L1 -0.4 -5.71 -0.3 2.41e-8 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.756 rs2901210 chr7:66017505 G/A cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.34e-9 Aortic root size; LIHC cis rs916888 0.821 rs199514 chr17:44856881 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs858239 0.571 rs2390755 chr7:23190716 A/T cg23682824 chr7:23144976 KLHL7 0.46 6.83 0.35 3.89e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs2262909 0.962 rs12610034 chr19:22314528 G/A cg17074339 chr11:11642133 GALNTL4 0.47 7.22 0.36 3.35e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC trans rs4342066 0.736 rs35374336 chr3:28371399 T/G cg11103623 chr3:57235255 HESX1 -0.37 -6.04 -0.31 4.03e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs4555082 0.874 rs2816611 chr14:105722976 G/C cg10792982 chr14:105748885 BRF1 0.45 6.18 0.32 1.85e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs2274273 0.840 rs10150760 chr14:55821548 C/T cg01864836 chr14:55583639 NA 0.38 6.67 0.34 1.05e-10 Protein biomarker; LIHC cis rs35306767 0.715 rs12772979 chr10:1034412 C/T cg20503657 chr10:835505 NA 0.84 7.52 0.38 4.8e-13 Eosinophil percentage of granulocytes; LIHC cis rs2576037 0.526 rs4890703 chr18:44522037 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.51 7.31 0.37 1.87e-12 Personality dimensions; LIHC cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.46 6.48 0.33 3.17e-10 Schizophrenia; LIHC cis rs2404602 0.669 rs9788684 chr15:77194838 A/T cg23625390 chr15:77176239 SCAPER 0.35 5.74 0.3 2.1e-8 Blood metabolite levels; LIHC cis rs2070488 0.965 rs7372386 chr3:38484175 C/G cg24069376 chr3:38537580 EXOG 0.41 7.48 0.37 6.42e-13 Electrocardiographic conduction measures; LIHC cis rs17125944 0.572 rs79312783 chr14:53250296 A/T cg13660082 chr14:53194042 PSMC6 -0.44 -7.77 -0.39 9.28e-14 Alzheimer's disease (late onset); LIHC cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.52 0.49 1.28e-22 Total body bone mineral density; LIHC cis rs17125944 0.686 rs12884504 chr14:53360494 G/A cg00686598 chr14:53173677 PSMC6 -0.8 -8.91 -0.43 3.18e-17 Alzheimer's disease (late onset); LIHC cis rs875971 0.895 rs1833495 chr7:65921595 T/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs317689 0.718 rs315122 chr12:69771073 G/T cg20891283 chr12:69753455 YEATS4 0.69 10.98 0.51 3.03e-24 Response to diuretic therapy; LIHC cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.55 -0.33 2.05e-10 Total body bone mineral density; LIHC cis rs7833986 0.534 rs2458083 chr8:56898785 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.87 8.76 0.43 9.08e-17 Height; LIHC cis rs8062405 0.755 rs55792032 chr16:28599411 A/G cg00204512 chr16:28754710 NA 0.41 7.18 0.36 4.49e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs55665837 0.519 rs1451677 chr11:14746012 A/C cg25251204 chr11:14927456 NA 0.42 6.0 0.31 5.12e-9 Vitamin D levels; LIHC cis rs2274273 1.000 rs67805055 chr14:55587552 C/T cg01864836 chr14:55583639 NA -0.36 -6.1 -0.31 2.79e-9 Protein biomarker; LIHC cis rs11030122 0.702 rs7128762 chr11:3943277 C/G cg18678763 chr11:4115507 RRM1 -0.58 -8.59 -0.42 3.07e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs68170813 0.641 rs12532953 chr7:106865920 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs12701220 0.522 rs868833 chr7:1054973 C/G cg07308232 chr7:1071921 C7orf50 -0.42 -5.9 -0.3 8.7e-9 Bronchopulmonary dysplasia; LIHC cis rs3118233 1 rs3118233 chr16:68733646 G/C cg01231543 chr16:68741748 NA 0.37 5.85 0.3 1.15e-8 Red cell distribution width; LIHC cis rs2607426 0.681 rs79361456 chr19:41240363 A/C cg20631044 chr19:41255890 C19orf54;SNRPA -0.52 -6.18 -0.32 1.78e-9 Blood protein levels; LIHC cis rs2239547 0.563 rs4302374 chr3:52905802 T/C cg11645453 chr3:52864694 ITIH4 0.33 8.22 0.41 4.28e-15 Schizophrenia; LIHC cis rs6684514 0.922 rs12022657 chr1:156314147 A/G cg16558208 chr1:156270281 VHLL 0.54 10.28 0.49 8.73e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs2032447 0.839 rs6901039 chr6:26000885 A/C cg03517284 chr6:25882590 NA -0.54 -6.88 -0.35 2.9100000000000002e-11 Intelligence (multi-trait analysis); LIHC cis rs539096 0.501 rs713191 chr1:44314553 A/G cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Intelligence (multi-trait analysis); LIHC cis rs2637030 0.559 rs256095 chr5:52972669 C/T cg06476337 chr5:52856530 NDUFS4 -0.4 -6.56 -0.33 1.98e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs8060686 0.623 rs12599178 chr16:68128104 A/G cg05110241 chr16:68378359 PRMT7 -0.48 -5.83 -0.3 1.27e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs4975616 0.686 rs37011 chr5:1348798 A/T cg06550200 chr5:1325588 CLPTM1L -0.61 -9.47 -0.46 4.93e-19 Lung cancer; LIHC cis rs344364 0.511 rs62040569 chr16:1948137 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs2070488 0.699 rs13064938 chr3:38440237 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.73 12.01 0.54 5.93e-28 Electrocardiographic conduction measures; LIHC cis rs3806843 1.000 rs2240695 chr5:140168151 G/T cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2602836 0.830 rs2602874 chr4:100039396 A/T cg13256891 chr4:100009986 ADH5 0.46 6.48 0.33 3.29e-10 HDL cholesterol;HDL cholesterol levels; LIHC cis rs6570726 0.791 rs392612 chr6:145881586 C/G cg23711669 chr6:146136114 FBXO30 -0.73 -13.5 -0.59 1.32e-33 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01181084 chr8:43059863 NA -0.43 -6.22 -0.32 1.47e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3099143 1.000 rs3102710 chr15:77061148 T/C cg21673338 chr15:77095150 SCAPER -0.49 -7.48 -0.37 6.4e-13 Recalcitrant atopic dermatitis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07550334 chr14:75518271 MLH3 0.46 6.11 0.31 2.67e-9 Lung function (FEV1/FVC); LIHC cis rs12220238 0.841 rs11001001 chr10:76097678 G/T cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.27 0.32 1.07e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg09913183 chr17:42254507 C17orf65;ASB16 0.79 12.07 0.55 3.43e-28 Total body bone mineral density; LIHC cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg02359409 chr6:42947317 PEX6 -0.47 -6.67 -0.34 1.03e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs801193 1.000 rs3857688 chr7:66127806 G/A cg18876405 chr7:65276391 NA -0.43 -7.37 -0.37 1.31e-12 Aortic root size; LIHC cis rs965469 0.696 rs6037570 chr20:3334292 C/A cg25506879 chr20:3388711 C20orf194 -0.55 -6.44 -0.33 3.99e-10 IFN-related cytopenia; LIHC cis rs77633900 0.772 rs284898 chr15:76750695 A/G cg21673338 chr15:77095150 SCAPER -0.51 -6.01 -0.31 4.72e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs9467773 0.649 rs2145318 chr6:26496603 T/A cg09904177 chr6:26538194 HMGN4 0.55 10.57 0.5 8.74e-23 Intelligence (multi-trait analysis); LIHC cis rs12762955 0.687 rs4880470 chr10:1077480 G/A cg18964960 chr10:1102726 WDR37 -0.51 -6.59 -0.34 1.62e-10 Response to angiotensin II receptor blocker therapy; LIHC cis rs9921222 0.521 rs78867928 chr16:368986 C/T cg12437481 chr16:420112 MRPL28 -0.62 -8.34 -0.41 1.83e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs12477438 0.798 rs1453562 chr2:99615850 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.92 -0.65 4.52e-43 Chronic sinus infection; LIHC cis rs16944613 0.541 rs6496690 chr15:91097401 T/C cg26821196 chr15:91095069 CRTC3 0.47 8.04 0.4 1.47e-14 Colorectal cancer; LIHC cis rs6442522 1.000 rs11918807 chr3:15446277 C/T cg16303742 chr3:15540471 COLQ 0.41 6.94 0.35 1.93e-11 Uric acid levels; LIHC cis rs2197308 0.606 rs2218397 chr12:38278307 C/T cg26384229 chr12:38710491 ALG10B -0.46 -6.14 -0.32 2.23e-9 Morning vs. evening chronotype; LIHC cis rs8062405 0.721 rs151181 chr16:28490517 A/G cg07382826 chr16:28625726 SULT1A1 0.4 6.58 0.34 1.76e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12530845 0.623 rs76485854 chr7:135352668 T/C cg23117316 chr7:135346802 PL-5283 -0.4 -5.78 -0.3 1.72e-8 Red blood cell traits; LIHC cis rs3806843 0.966 rs2563267 chr5:140136913 C/T cg19875535 chr5:140030758 IK -0.37 -6.02 -0.31 4.48e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs6542838 0.580 rs1607256 chr2:99543444 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.42 -5.97 -0.31 5.89e-9 Fear of minor pain; LIHC cis rs2842992 0.724 rs2273827 chr6:160211339 C/A cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.14 0.44 5.61e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs9549328 0.718 rs7139939 chr13:113634409 G/A cg00071026 chr13:113650936 MCF2L -0.38 -5.93 -0.31 7.3e-9 Systolic blood pressure; LIHC cis rs8177253 1.000 rs8177261 chr3:133480588 A/C cg12373951 chr3:133503437 NA 0.69 12.44 0.56 1.41e-29 Iron status biomarkers; LIHC cis rs1144333 0.655 rs4949682 chr1:76443196 C/T cg10523679 chr1:76189770 ACADM -0.46 -6.17 -0.32 1.93e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs12980942 0.872 rs3752705 chr19:41798111 A/G cg25627403 chr19:41769009 HNRNPUL1 0.5 6.3 0.32 9.22e-10 Coronary artery disease; LIHC cis rs908922 0.676 rs3753451 chr1:152485227 T/G cg20991723 chr1:152506922 NA 0.5 8.45 0.42 8.79e-16 Hair morphology; LIHC cis rs2404602 0.735 rs11072598 chr15:76764788 T/C cg23625390 chr15:77176239 SCAPER -0.49 -8.05 -0.4 1.42e-14 Blood metabolite levels; LIHC cis rs3204270 0.639 rs6565620 chr17:79658100 C/T cg18367735 chr17:79674897 NA 0.72 8.47 0.42 7.35e-16 Dental caries; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02664216 chr12:19592651 AEBP2 0.42 6.54 0.33 2.18e-10 Cognitive function; LIHC cis rs72615157 0.539 rs12673441 chr7:99670328 A/T cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.4 5.71 0.3 2.43e-8 Lung function (FEV1/FVC); LIHC cis rs6570726 1.000 rs455109 chr6:145872665 C/T cg23711669 chr6:146136114 FBXO30 0.53 9.26 0.45 2.4e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs2050392 0.557 rs306588 chr10:30723593 G/A cg02070205 chr10:30722105 MAP3K8 -0.43 -5.77 -0.3 1.75e-8 Inflammatory bowel disease; LIHC cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg23758822 chr17:41437982 NA 0.94 17.49 0.69 2.15e-49 Menopause (age at onset); LIHC cis rs4700695 0.545 rs253275 chr5:65509809 A/G cg21114390 chr5:65439923 SFRS12 -0.52 -7.69 -0.38 1.62e-13 Facial morphology (factor 19); LIHC cis rs1997103 1.000 rs6951294 chr7:55400835 C/T cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs4713118 0.869 rs9461405 chr6:27719375 G/T cg20933634 chr6:27740509 NA 0.46 6.04 0.31 4.06e-9 Parkinson's disease; LIHC cis rs1003719 0.646 rs7276711 chr21:38578189 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs1018836 0.923 rs756569 chr8:91610957 G/A cg16814680 chr8:91681699 NA -0.64 -10.56 -0.5 9.85e-23 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4819052 0.885 rs28576202 chr21:46674684 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.48 0.53 4.87e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg12463550 chr7:65579703 CRCP 0.67 7.18 0.36 4.48e-12 Diabetic kidney disease; LIHC trans rs66887589 0.616 rs11098497 chr4:120187068 C/T cg25214090 chr10:38739885 LOC399744 0.43 6.87 0.35 3.06e-11 Diastolic blood pressure; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg00958676 chr8:9911641 MSRA -0.62 -6.39 -0.33 5.49e-10 Obesity-related traits; LIHC trans rs12478296 1.000 rs56292923 chr2:243039986 C/T cg01596870 chr19:55963115 NA -0.63 -8.16 -0.4 6.49e-15 Obesity-related traits; LIHC cis rs7618501 0.602 rs2624816 chr3:50117312 T/G cg24110177 chr3:50126178 RBM5 0.53 8.55 0.42 4.03e-16 Intelligence (multi-trait analysis); LIHC cis rs311392 0.554 rs311423 chr8:55104694 G/A cg20636351 chr8:55087400 NA -0.34 -7.1 -0.36 7.46e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg09455208 chr3:40491958 NA 0.34 6.63 0.34 1.32e-10 Renal cell carcinoma; LIHC cis rs9768139 0.634 rs56389048 chr7:158121368 T/A cg25566285 chr7:158114605 PTPRN2 0.23 6.13 0.31 2.39e-9 Calcium levels; LIHC cis rs2197308 0.626 rs6581156 chr12:37858731 C/A cg26384229 chr12:38710491 ALG10B -0.48 -6.85 -0.35 3.46e-11 Morning vs. evening chronotype; LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg24503407 chr1:205819492 PM20D1 0.73 10.37 0.49 4.46e-22 Menarche (age at onset); LIHC trans rs634534 0.622 rs1192168 chr11:65730945 T/G cg17712092 chr4:129076599 LARP1B 0.7 11.62 0.53 1.51e-26 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs1914816 0.887 rs2460155 chr15:76478925 C/T cg03037974 chr15:76606532 NA -0.6 -5.96 -0.31 6.25e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs10256972 0.524 rs6945202 chr7:1116558 T/C cg23978390 chr7:1156363 C7orf50 0.47 6.78 0.34 5.15e-11 Longevity;Endometriosis; LIHC cis rs17331151 0.573 rs28552648 chr3:52865593 G/A cg04865290 chr3:52927548 TMEM110 -0.42 -6.34 -0.32 7.28e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg25894440 chr7:65020034 NA -0.52 -6.12 -0.31 2.54e-9 Diabetic kidney disease; LIHC cis rs13217239 0.646 rs11756275 chr6:27007113 A/C cg18867708 chr6:26865862 GUSBL1 -0.52 -7.96 -0.4 2.57e-14 Schizophrenia; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs929354 0.557 rs62491947 chr7:156960813 G/A cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg21448741 chr8:58168803 NA 0.35 6.09 0.31 3.02e-9 Developmental language disorder (linguistic errors); LIHC cis rs17539620 0.624 rs62432739 chr6:154835926 A/G cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg16132339 chr22:24313637 DDTL;DDT 0.66 11.67 0.53 9.94e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12540874 0.500 rs12719030 chr7:50485073 T/C cg18232548 chr7:50535776 DDC -0.44 -6.23 -0.32 1.36e-9 Systemic sclerosis; LIHC cis rs798554 0.679 rs1639036 chr7:2885089 G/A cg04166393 chr7:2884313 GNA12 0.51 8.28 0.41 2.74e-15 Height; LIHC cis rs929354 0.772 rs3802126 chr7:156970281 G/A cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs6669384 0.723 rs4844395 chr1:208037967 A/G cg22525895 chr1:207977042 MIR29B2 0.56 6.23 0.32 1.34e-9 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC cis rs17106184 1.000 rs72898961 chr1:50966976 G/A cg07174182 chr1:51127561 FAF1 -0.64 -6.75 -0.34 6.45e-11 Type 2 diabetes; LIHC cis rs7613875 0.600 rs7061 chr3:50114515 C/T cg05623727 chr3:50126028 RBM5 -0.35 -6.14 -0.32 2.25e-9 Body mass index; LIHC cis rs36051895 0.623 rs2181115 chr9:5263058 G/A cg02405213 chr9:5042618 JAK2 -0.64 -10.23 -0.48 1.31e-21 Pediatric autoimmune diseases; LIHC cis rs4272321 1 rs4272321 chr7:157951835 A/G cg23602909 chr7:157956050 PTPRN2 -0.31 -10.19 -0.48 1.83e-21 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; LIHC cis rs9534288 0.797 rs9534282 chr13:46588944 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC trans rs1499614 1.000 rs2141924 chr7:66186246 C/T cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs559928 0.556 rs11607903 chr11:63932140 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.4 0.37 1.06e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs16858210 0.874 rs35717944 chr3:183607361 C/A cg25686905 chr3:183603175 PARL -0.5 -9.32 -0.45 1.45e-18 Menopause (age at onset); LIHC cis rs2797160 1.000 rs1935772 chr6:125994708 T/C cg05901451 chr6:126070800 HEY2 -0.4 -6.68 -0.34 9.54e-11 Endometrial cancer; LIHC cis rs2073499 1.000 rs6776145 chr3:50316119 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.86 -13.81 -0.6 8.62e-35 Schizophrenia; LIHC cis rs2070433 0.706 rs2268524 chr21:47838700 C/T cg12379764 chr21:47803548 PCNT 0.7 9.85 0.47 2.5e-20 Lymphocyte counts; LIHC cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg08219700 chr8:58056026 NA 0.52 6.29 0.32 9.5e-10 Developmental language disorder (linguistic errors); LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.22 -0.32 1.49e-9 Diastolic blood pressure; LIHC cis rs644799 0.710 rs564480 chr11:95561741 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.78 12.18 0.55 1.31e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs758324 0.947 rs72793241 chr5:131240885 C/T cg06307176 chr5:131281290 NA -0.4 -5.79 -0.3 1.6e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs10779751 1.000 rs11121698 chr1:11267283 C/T cg08854313 chr1:11322531 MTOR 0.86 15.56 0.64 1.14e-41 Body mass index; LIHC cis rs875971 1.000 rs1968225 chr7:65874773 T/C cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs1801251 0.963 rs7591176 chr2:233581803 C/A cg25237894 chr2:233734115 C2orf82 0.58 11.25 0.52 3.55e-25 Coronary artery disease; LIHC cis rs61677309 1.000 rs56346212 chr11:118172342 T/A cg06090739 chr11:118230722 UBE4A 0.34 6.32 0.32 7.96e-10 Lung cancer in ever smokers; LIHC cis rs2760061 0.603 rs697761 chr1:228192397 G/A cg01200585 chr1:228362443 C1orf69 0.49 6.24 0.32 1.26e-9 Diastolic blood pressure; LIHC cis rs986417 0.818 rs7156317 chr14:61087740 G/A cg27398547 chr14:60952738 C14orf39 0.67 7.42 0.37 9.41e-13 Gut microbiota (bacterial taxa); LIHC cis rs12744310 1.000 rs34027267 chr1:41756677 T/C cg03962019 chr1:41807865 NA 0.38 6.1 0.31 2.82e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7903847 0.619 rs10786336 chr10:99134953 A/C cg20016023 chr10:99160130 RRP12 -0.41 -6.48 -0.33 3.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg23131131 chr22:24373011 LOC391322 0.69 9.98 0.47 9.63e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9902453 0.967 rs11080121 chr17:28528842 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 9.1 0.44 7.65e-18 Coffee consumption (cups per day); LIHC cis rs4665809 1.000 rs10048648 chr2:26320315 T/C cg04944784 chr2:26401820 FAM59B -0.64 -8.21 -0.41 4.74e-15 Gut microbiome composition (summer); LIHC cis rs743757 1.000 rs734767 chr3:50431410 C/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.54 8.63 0.42 2.39e-16 Diastolic blood pressure; LIHC cis rs60871478 1.000 rs62432253 chr7:802928 A/G cg27478167 chr7:817139 HEATR2 -0.51 -6.81 -0.35 4.52e-11 Cerebrospinal P-tau181p levels; LIHC cis rs854765 0.583 rs2350977 chr17:17802779 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.45 7.81 0.39 7.32e-14 Total body bone mineral density; LIHC cis rs910316 1.000 rs11623413 chr14:75588824 C/T cg08847533 chr14:75593920 NEK9 -0.89 -19.76 -0.73 1.55e-58 Height; LIHC cis rs10089 1.000 rs10089 chr5:127522543 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.39 0.33 5.27e-10 Ileal carcinoids; LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg01646665 chr1:156251436 TMEM79;SMG5 0.3 5.8 0.3 1.5e-8 Tonsillectomy; LIHC cis rs941408 1.000 rs1736182 chr19:2798686 T/G cg02580895 chr19:2754563 NA -0.41 -6.04 -0.31 3.96e-9 Total cholesterol levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg27010136 chr7:1131122 GPER;C7orf50 -0.39 -6.22 -0.32 1.48e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9534288 0.797 rs7331368 chr13:46609062 G/C cg15192986 chr13:46630673 CPB2 -0.55 -8.46 -0.42 8.04e-16 Blood protein levels; LIHC cis rs7212590 0.655 rs8070039 chr17:57973585 G/C cg10252138 chr17:58120427 NA -0.62 -6.64 -0.34 1.23e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs11190604 1.000 rs10883499 chr10:102232188 T/A cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9393692 0.905 rs6931391 chr6:26279235 G/C cg05868516 chr6:26286170 HIST1H4H 0.41 6.25 0.32 1.21e-9 Educational attainment; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20278634 chr1:36274212 EIF2C4 0.45 6.58 0.34 1.82e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs765787 0.530 rs4442750 chr15:45535328 G/T cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs9486719 0.947 rs2472908 chr6:96875998 A/T cg06623918 chr6:96969491 KIAA0776 0.73 7.18 0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg17971929 chr21:40555470 PSMG1 0.83 9.95 0.47 1.23e-20 Cognitive function; LIHC cis rs2404602 0.536 rs1587381 chr15:76769620 G/A cg03037974 chr15:76606532 NA 0.76 14.68 0.62 3.63e-38 Blood metabolite levels; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg19635926 chr16:89946313 TCF25 -0.5 -7.23 -0.36 3.28e-12 Skin colour saturation; LIHC cis rs1029738 0.615 rs717624 chr7:22894487 T/C cg22407942 chr7:22894828 SNORD93 -0.34 -6.39 -0.33 5.42e-10 Fibrinogen levels; LIHC cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.94 0.31 7.12e-9 Bipolar disorder; LIHC cis rs7818688 0.697 rs78802294 chr8:95977974 G/A cg16049864 chr8:95962084 TP53INP1 0.62 6.77 0.34 5.73e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg11070056 chr1:107600091 PRMT6 0.63 10.95 0.51 3.98e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2439831 0.867 rs2447211 chr15:43936351 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.65 9.18 0.44 4.05e-18 Lung cancer in ever smokers; LIHC trans rs3112255 0.967 rs2015067 chr2:101305478 T/C cg06958034 chr1:23346203 KDM1A -0.45 -6.05 -0.31 3.77e-9 Intelligence (multi-trait analysis); LIHC trans rs1864585 0.505 rs73208792 chr8:10680471 C/T cg20373634 chr10:103911536 NOLC1 -0.46 -6.1 -0.31 2.92e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.1 -0.36 7.1e-12 Diabetic kidney disease; LIHC cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Bipolar disorder; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg14411527 chr7:55640598 VOPP1 0.49 6.26 0.32 1.19e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs10540 0.818 rs12806089 chr11:501468 G/A cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.15e-11 Body mass index; LIHC trans rs9641123 0.639 rs7341502 chr7:93229453 C/T cg09745688 chr16:2908918 PRSS22 -0.37 -6.46 -0.33 3.6e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs2979489 0.891 rs17626867 chr8:30311177 G/T cg26383811 chr8:30366931 RBPMS -0.73 -12.28 -0.55 5.6e-29 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs10791323 0.720 rs2851117 chr11:133705905 A/G cg06766960 chr11:133703094 NA 0.58 9.37 0.45 1.04e-18 Childhood ear infection; LIHC trans rs7246657 0.943 rs7255407 chr19:37933936 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs941408 0.515 rs1640262 chr19:2779134 C/T cg02580895 chr19:2754563 NA 0.47 7.04 0.36 1.09e-11 Total cholesterol levels; LIHC cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg04267008 chr7:1944627 MAD1L1 -0.66 -10.39 -0.49 3.59e-22 Bipolar disorder and schizophrenia; LIHC cis rs17685 0.712 rs6954569 chr7:75738885 T/A cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.89e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1451375 0.550 rs10239830 chr7:50603829 A/G cg14593290 chr7:50529359 DDC 0.62 9.79 0.47 4.21e-20 Malaria; LIHC cis rs1577917 0.958 rs11752180 chr6:86573165 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.22 -0.41 4.25e-15 Response to antipsychotic treatment; LIHC cis rs7020830 0.830 rs308499 chr9:37348059 C/G cg14294708 chr9:37120828 ZCCHC7 0.92 18.16 0.7 4.43e-52 Schizophrenia; LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg18279126 chr7:2041391 MAD1L1 0.37 6.11 0.31 2.66e-9 Bipolar disorder and schizophrenia; LIHC cis rs35110281 0.774 rs162404 chr21:44963264 G/A cg21573476 chr21:45109991 RRP1B -0.52 -9.53 -0.46 3.08e-19 Mean corpuscular volume; LIHC cis rs79839061 0.656 rs3775126 chr4:886345 C/T cg07828340 chr4:882639 GAK 0.86 7.54 0.38 4.2e-13 Intelligence (multi-trait analysis); LIHC cis rs1997103 1.000 rs10252413 chr7:55396740 C/G cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.68 0.38 1.65e-13 Prudent dietary pattern; LIHC cis rs9902453 0.679 rs2054847 chr17:28532013 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.56 8.47 0.42 7.42e-16 Coffee consumption (cups per day); LIHC cis rs4690686 0.808 rs6553945 chr4:177270965 T/C cg17059388 chr4:177262070 NA 0.35 6.55 0.33 2.12e-10 Essential tremor; LIHC cis rs8062405 0.755 rs62034350 chr16:28562256 A/G cg00204512 chr16:28754710 NA 0.41 7.16 0.36 4.9e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs12477438 0.765 rs4851183 chr2:99629149 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.59 -0.5 7.31e-23 Chronic sinus infection; LIHC cis rs7107174 0.681 rs10899499 chr11:78124797 A/G cg02023728 chr11:77925099 USP35 -0.42 -7.67 -0.38 1.81e-13 Testicular germ cell tumor; LIHC cis rs2033711 0.837 rs3764535 chr19:58929052 G/A cg13877915 chr19:58951672 ZNF132 0.53 8.01 0.4 1.8e-14 Uric acid clearance; LIHC cis rs12477438 0.561 rs2084988 chr2:99655755 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs2070488 0.931 rs7630012 chr3:38552250 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.54 -0.62 1.29e-37 Electrocardiographic conduction measures; LIHC cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg26818010 chr10:134567672 INPP5A -0.8 -9.8 -0.47 3.9e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs703842 0.964 rs10431552 chr12:58178148 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.86 14.25 0.61 1.74e-36 Multiple sclerosis; LIHC cis rs1707322 1.000 rs10890377 chr1:46406594 G/A cg03146154 chr1:46216737 IPP 0.48 7.85 0.39 5.51e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3015497 0.616 rs4901044 chr14:51090295 A/G cg09863266 chr14:51125203 SAV1 -0.39 -6.18 -0.32 1.85e-9 Mean platelet volume; LIHC cis rs3015497 0.763 rs2934689 chr14:51118327 A/C cg09863266 chr14:51125203 SAV1 -0.43 -6.84 -0.35 3.61e-11 Mean platelet volume; LIHC cis rs7224685 0.906 rs2278524 chr17:4081975 A/G cg09597638 chr17:3907349 NA -0.5 -7.67 -0.38 1.85e-13 Type 2 diabetes; LIHC cis rs4906332 1.000 rs55930273 chr14:103960298 G/A cg19000871 chr14:103996768 TRMT61A -0.46 -7.86 -0.39 5.04e-14 Coronary artery disease; LIHC cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.18 0.32 1.81e-9 Alzheimer's disease; LIHC cis rs9911578 0.967 rs8072712 chr17:57162464 A/T cg12560992 chr17:57184187 TRIM37 0.97 17.94 0.7 3.35e-51 Intelligence (multi-trait analysis); LIHC cis rs11758351 1.000 rs17598927 chr6:26184640 C/G cg06951627 chr6:26196580 NA -0.53 -5.92 -0.3 7.75e-9 Gout;Renal underexcretion gout; LIHC cis rs11718455 0.960 rs13082990 chr3:44005172 T/C cg08738300 chr3:44038990 NA 0.52 9.07 0.44 9.26e-18 Coronary artery disease; LIHC cis rs74233809 0.901 rs7098825 chr10:104628234 T/C cg03493300 chr10:104813866 CNNM2 0.43 5.77 0.3 1.79e-8 Birth weight; LIHC cis rs11628318 0.515 rs7152144 chr14:103126101 C/T cg23461800 chr14:103021989 NA 0.38 5.74 0.3 2.06e-8 Platelet count; LIHC trans rs10152207 1.000 rs12595513 chr15:38150151 C/T cg04477917 chr16:71660055 MARVELD3 0.6 6.19 0.32 1.74e-9 Survival in rectal cancer; LIHC cis rs6138458 0.626 rs6050261 chr20:25014206 C/T cg26195577 chr20:24973756 C20orf3 0.75 9.32 0.45 1.43e-18 Blood protein levels; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg16132339 chr22:24313637 DDTL;DDT 0.66 11.66 0.53 1.1e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs7534824 0.543 rs1074739 chr1:101362371 C/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 7.33 0.37 1.69e-12 Refractive astigmatism; LIHC cis rs9399135 0.967 rs4896119 chr6:135293391 C/T cg22676075 chr6:135203613 NA 0.4 6.45 0.33 3.86e-10 Red blood cell count; LIHC cis rs1499614 1.000 rs2707838 chr7:66159201 C/T cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC cis rs17253792 0.822 rs8009239 chr14:56062490 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs9916302 0.851 rs7220650 chr17:37487168 A/G cg07936489 chr17:37558343 FBXL20 0.83 13.48 0.59 1.59e-33 Glomerular filtration rate (creatinine); LIHC trans rs7714584 1.000 rs3906527 chr5:150266392 T/A cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs1865760 0.516 rs9393684 chr6:26075531 G/C cg18357526 chr6:26021779 HIST1H4A 0.48 6.97 0.35 1.64e-11 Height; LIHC trans rs11098499 0.738 rs34566984 chr4:120361270 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs9733 0.566 rs112967224 chr1:150677263 G/A cg17724175 chr1:150552817 MCL1 0.48 9.74 0.47 6.17e-20 Tonsillectomy; LIHC cis rs116095464 0.510 rs60844864 chr5:267000 A/G cg22857025 chr5:266934 NA -1.51 -18.3 -0.7 1.23e-52 Breast cancer; LIHC cis rs7246657 0.943 rs10403613 chr19:37844306 C/T cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg01765077 chr12:122356316 WDR66 0.56 7.44 0.37 7.97e-13 Mean corpuscular volume; LIHC cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 -1.02 -10.36 -0.49 4.51e-22 Platelet count; LIHC cis rs2645694 0.626 rs2645704 chr4:77830805 T/C cg03477792 chr4:77819574 ANKRD56 0.56 7.52 0.38 4.81e-13 Emphysema distribution in smoking; LIHC cis rs651907 0.535 rs13065944 chr3:101473088 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.4 0.52 9.54e-26 Colorectal cancer; LIHC cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg01788221 chr16:89496183 ANKRD11 -0.39 -6.06 -0.31 3.59e-9 Multiple myeloma (IgH translocation); LIHC cis rs903552 0.932 rs9806551 chr15:102008206 C/T cg00659931 chr15:102010125 PCSK6 -0.5 -6.88 -0.35 2.84e-11 Diabetic kidney disease; LIHC cis rs6570726 1.000 rs6570699 chr6:145920732 G/A cg23711669 chr6:146136114 FBXO30 0.54 9.14 0.44 5.49e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg25364880 chr3:44379878 C3orf23 -0.51 -7.22 -0.36 3.42e-12 Depressive symptoms; LIHC cis rs13217239 0.646 rs10456351 chr6:26986792 C/T cg12292205 chr6:26970375 C6orf41 0.45 7.76 0.39 1.02e-13 Schizophrenia; LIHC cis rs10752881 1.000 rs6673559 chr1:182983197 G/C ch.1.3577855R chr1:183094577 LAMC1 0.58 10.09 0.48 4.09e-21 Colorectal cancer; LIHC trans rs1814175 0.645 rs10839448 chr11:49938930 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.82 0.35 4.17e-11 Height; LIHC cis rs11719291 0.584 rs13080725 chr3:49076092 G/A cg06212747 chr3:49208901 KLHDC8B -0.69 -5.91 -0.3 8.11e-9 Cognitive function; LIHC cis rs7223966 1.000 rs11657081 chr17:61792339 C/T cg05941027 chr17:61774174 LIMD2 0.3 6.34 0.32 7.31e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs72627509 0.951 rs6554401 chr4:57825336 C/G cg26694713 chr4:57773883 REST 0.67 9.62 0.46 1.56e-19 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs875971 0.545 rs2420612 chr7:66001812 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.34 6.76 0.34 5.96e-11 Aortic root size; LIHC cis rs11608355 0.545 rs2302705 chr12:109898716 C/T cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.6 8.5 0.42 5.85e-16 Lymphocyte counts; LIHC cis rs400736 0.671 rs2472862 chr1:7991203 G/A cg25007680 chr1:8021821 PARK7 -0.43 -6.75 -0.34 6.46e-11 Response to antidepressants and depression; LIHC cis rs743757 1.000 rs2236965 chr3:50453456 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.53 8.3 0.41 2.49e-15 Diastolic blood pressure; LIHC cis rs72627509 0.638 rs78933653 chr4:57854840 A/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.64 -9.21 -0.45 3.27e-18 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1029738 0.500 rs13227008 chr7:22883708 C/T cg11367502 chr7:22862612 TOMM7 -0.35 -5.82 -0.3 1.33e-8 Fibrinogen levels; LIHC cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg17971929 chr21:40555470 PSMG1 0.85 10.14 0.48 2.66e-21 Cognitive function; LIHC cis rs17685 0.712 rs9800948 chr7:75810473 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.36 -5.93 -0.31 7.46e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg13012494 chr21:47604986 C21orf56 -0.38 -5.83 -0.3 1.31e-8 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC cis rs875971 1.000 rs6963646 chr7:65685767 T/C cg18876405 chr7:65276391 NA -0.38 -6.88 -0.35 2.82e-11 Aortic root size; LIHC cis rs2273669 0.667 rs12196024 chr6:109302258 C/T cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.43 -0.41 1e-15 Lymphocyte counts; LIHC cis rs8180040 0.726 rs2061197 chr3:47001350 C/T cg16586182 chr3:47516702 SCAP 0.49 8.67 0.42 1.73e-16 Colorectal cancer; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg03874509 chr1:107600012 PRMT6 0.72 11.72 0.54 6.52e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17711722 0.583 rs10085415 chr7:65093568 T/A cg14393609 chr7:65229607 NA -0.39 -5.73 -0.3 2.26e-8 Calcium levels; LIHC cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg05665937 chr4:1216051 CTBP1 0.46 6.09 0.31 3.11e-9 Obesity-related traits; LIHC cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.7 0.53 7.79e-27 Alzheimer's disease; LIHC cis rs6430585 0.583 rs7581814 chr2:136641593 C/G cg07169764 chr2:136633963 MCM6 -1.31 -22.74 -0.78 2.29e-70 Corneal structure; LIHC cis rs6121246 0.542 rs6059761 chr20:30110522 G/C cg13852791 chr20:30311386 BCL2L1 0.73 6.32 0.32 8.17e-10 Mean corpuscular hemoglobin; LIHC cis rs9399135 0.967 rs12527683 chr6:135324534 C/T cg22676075 chr6:135203613 NA 0.4 6.56 0.33 1.96e-10 Red blood cell count; LIHC cis rs7762018 0.891 rs3749882 chr6:170151766 C/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.56 6.89 0.35 2.73e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6840360 0.571 rs11723395 chr4:152524191 G/A cg22705602 chr4:152727874 NA -0.32 -6.22 -0.32 1.43e-9 Intelligence (multi-trait analysis); LIHC cis rs365132 0.875 rs353477 chr5:176418927 C/T cg16309518 chr5:176445507 NA -0.53 -9.96 -0.47 1.06e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs2153535 0.521 rs6939827 chr6:8461360 C/G cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.21e-16 Motion sickness; LIHC cis rs11229555 0.645 rs11229549 chr11:58395914 T/C cg15696309 chr11:58395628 NA -0.69 -6.37 -0.33 6.13e-10 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs10193935 0.892 rs13413028 chr2:42394865 C/G cg27598129 chr2:42591480 NA -0.73 -11.29 -0.52 2.5e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs11031096 0.502 rs4910875 chr11:4047855 C/G cg18678763 chr11:4115507 RRM1 -0.56 -8.25 -0.41 3.56e-15 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs62458065 0.513 rs702831 chr7:32579715 C/T cg20159608 chr7:32802032 NA -0.51 -6.1 -0.31 2.89e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs9549367 0.789 rs3764125 chr13:113897648 A/G cg00898013 chr13:113819073 PROZ 0.42 7.08 0.36 8.23e-12 Platelet distribution width; LIHC cis rs10916814 1.000 rs72649163 chr1:20900592 G/C cg24502330 chr1:20914028 CDA -0.28 -5.86 -0.3 1.1e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs12458462 0.892 rs2007483 chr18:77476131 A/T cg11879182 chr18:77439856 CTDP1 0.82 13.84 0.6 6.45e-35 Monocyte count; LIHC cis rs533581 0.866 rs475796 chr16:88970776 C/G cg03970086 chr16:88974840 CBFA2T3 0.35 6.75 0.34 6.25e-11 Social autistic-like traits; LIHC cis rs2153535 0.580 rs1577470 chr6:8462426 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.57 0.53 2.46e-26 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06617136 chr1:145470297 ANKRD34A;POLR3GL 0.41 6.09 0.31 3.06e-9 Pancreatic cancer; LIHC trans rs7618501 1.000 rs7648987 chr3:49868455 A/G cg21582582 chr3:182698605 DCUN1D1 0.54 7.13 0.36 5.97e-12 Intelligence (multi-trait analysis); LIHC cis rs2115630 0.645 rs1107179 chr15:85198362 A/C cg12501888 chr15:85177176 SCAND2 0.47 7.08 0.36 8.21e-12 P wave terminal force; LIHC cis rs916888 0.773 rs538628 chr17:44787313 G/C cg01570182 chr17:44337453 NA 1.0 9.98 0.47 9.59e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4332037 0.588 rs61409925 chr7:1971226 G/A cg23422044 chr7:1970798 MAD1L1 -0.66 -7.24 -0.36 2.9e-12 Bipolar disorder; LIHC cis rs7613875 0.620 rs17657688 chr3:50033228 C/T cg05623727 chr3:50126028 RBM5 -0.33 -5.76 -0.3 1.91e-8 Body mass index; LIHC cis rs17401966 0.858 rs61778404 chr1:10432879 A/G cg19773385 chr1:10388646 KIF1B -0.39 -6.66 -0.34 1.13e-10 Hepatocellular carcinoma; LIHC cis rs8020095 0.528 rs73279056 chr14:67701536 T/G cg03487553 chr14:67822707 ATP6V1D -0.35 -6.07 -0.31 3.32e-9 Depression (quantitative trait); LIHC cis rs1494950 1.000 rs7675235 chr4:15063390 A/T cg12377275 chr4:15005593 CPEB2 -0.87 -7.42 -0.37 9.28e-13 Political ideology; LIHC cis rs1707322 0.691 rs61784799 chr1:46177748 A/G cg06784218 chr1:46089804 CCDC17 -0.41 -7.22 -0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7772486 0.790 rs2265919 chr6:146221753 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.78 -0.3 1.65e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs5753618 0.561 rs715510 chr22:31690528 T/A cg22777020 chr22:31556080 RNF185 -0.55 -6.35 -0.32 6.77e-10 Colorectal cancer; LIHC cis rs9910055 0.530 rs11652651 chr17:42302907 A/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.42 -7.37 -0.37 1.29e-12 Total body bone mineral density; LIHC cis rs3770081 1.000 rs60981340 chr2:86177046 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -8.82 -0.43 6.02e-17 Facial emotion recognition (sad faces); LIHC cis rs79057730 0.527 rs35316052 chr7:802954 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.81 8.82 0.43 5.9e-17 Initial pursuit acceleration; LIHC cis rs950776 0.593 rs555018 chr15:78879242 G/A cg06917634 chr15:78832804 PSMA4 -0.74 -10.12 -0.48 3.14e-21 Sudden cardiac arrest; LIHC trans rs4596713 0.538 rs7865373 chr9:71765105 T/C cg16512924 chr15:28394682 HERC2 0.4 6.41 0.33 4.8e-10 Headache; LIHC cis rs3812111 0.676 rs9488845 chr6:116452658 C/A cg08036074 chr6:116424633 NT5DC1 -0.5 -8.51 -0.42 5.47e-16 Age-related macular degeneration; LIHC trans rs61931739 0.500 rs11053290 chr12:34582392 C/T cg26384229 chr12:38710491 ALG10B -0.64 -8.19 -0.4 5.41e-15 Morning vs. evening chronotype; LIHC trans rs60752752 0.852 rs6702735 chr1:153370917 C/T cg14901121 chr8:98817630 LAPTM4B -0.43 -7.09 -0.36 7.9e-12 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs12477438 0.748 rs10200974 chr2:99675227 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg05665937 chr4:1216051 CTBP1 0.39 6.2 0.32 1.59e-9 Obesity-related traits; LIHC cis rs7408868 1.000 rs757475 chr19:15273749 C/T cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC cis rs7208859 0.673 rs73265612 chr17:29225983 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6442522 0.533 rs2100545 chr3:15521619 C/T cg16303742 chr3:15540471 COLQ 0.37 6.0 0.31 4.94e-9 Uric acid levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02287918 chr21:30396957 USP16 0.62 8.56 0.42 3.86e-16 Lung function (FEV1/FVC); LIHC cis rs514406 0.825 rs487453 chr1:53271225 T/C cg08859206 chr1:53392774 SCP2 0.38 6.19 0.32 1.71e-9 Monocyte count; LIHC cis rs11711311 1.000 rs12631232 chr3:113497386 C/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 8.86 0.43 4.29e-17 IgG glycosylation; LIHC cis rs7959452 0.503 rs7300266 chr12:69654187 A/G cg14784868 chr12:69753453 YEATS4 0.81 15.03 0.63 1.54e-39 Blood protein levels; LIHC cis rs1419980 0.730 rs11054890 chr12:7773096 T/C cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC cis rs831571 0.668 rs34723451 chr3:64081836 G/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.5 -5.86 -0.3 1.08e-8 Type 2 diabetes; LIHC trans rs4906332 1.000 rs7155822 chr14:103922390 A/G cg17675199 chr6:35436792 RPL10A 0.35 6.78 0.34 5.2e-11 Coronary artery disease; LIHC cis rs1865760 0.566 rs10807006 chr6:26048752 C/A cg17691542 chr6:26056736 HIST1H1C 0.4 5.74 0.3 2.07e-8 Height; LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg09455208 chr3:40491958 NA 0.39 7.92 0.39 3.4e-14 Renal cell carcinoma; LIHC cis rs372883 0.600 rs1153277 chr21:30666867 A/T cg24692254 chr21:30365293 RNF160 -0.49 -6.13 -0.31 2.37e-9 Pancreatic cancer; LIHC cis rs950169 0.922 rs11633075 chr15:85113972 C/A cg17507749 chr15:85114479 UBE2QP1 0.78 8.96 0.44 2.12e-17 Schizophrenia; LIHC cis rs11630290 0.640 rs1811744 chr15:64167428 T/C cg12036633 chr15:63758958 NA 0.57 5.96 0.31 6.42e-9 Iris characteristics; LIHC cis rs801193 0.660 rs2659897 chr7:66187715 A/G cg18876405 chr7:65276391 NA -0.34 -6.14 -0.32 2.29e-9 Aortic root size; LIHC cis rs9921222 0.786 rs3848365 chr16:374617 C/T cg12437481 chr16:420112 MRPL28 -0.46 -6.16 -0.32 2.07e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs870825 0.587 rs35377170 chr4:185639728 T/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg10295955 chr4:187884368 NA -0.99 -22.13 -0.77 5.79e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 0.850 rs2238531 chr16:89856217 C/G cg00800038 chr16:89945340 TCF25 -0.6 -8.5 -0.42 5.92e-16 Skin colour saturation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13648088 chr10:124768538 ACADSB;IKZF5 0.59 7.73 0.39 1.2e-13 Lung function (FEV1/FVC); LIHC cis rs12477438 0.539 rs13394175 chr2:99590713 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.69 -9.55 -0.46 2.5e-19 Chronic sinus infection; LIHC cis rs11997175 0.766 rs6983113 chr8:33699513 G/A cg04338863 chr8:33670619 NA 0.31 5.74 0.3 2.14e-8 Body mass index; LIHC cis rs28830936 0.934 rs28401754 chr15:42116903 T/C cg17847044 chr15:42102381 MAPKBP1 -0.31 -5.97 -0.31 5.9e-9 Diastolic blood pressure; LIHC cis rs7208859 0.623 rs11656844 chr17:29060597 G/T cg13385521 chr17:29058706 SUZ12P 0.84 8.37 0.41 1.49e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg19318889 chr4:1322082 MAEA -0.64 -10.38 -0.49 4.02e-22 Longevity; LIHC cis rs7772486 0.686 rs1337839 chr6:146010239 A/G cg23711669 chr6:146136114 FBXO30 -0.61 -10.12 -0.48 3.11e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg02353165 chr6:42928485 GNMT 0.75 11.81 0.54 3.25e-27 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs11098499 0.954 rs11729521 chr4:120416788 T/C cg25214090 chr10:38739885 LOC399744 0.58 9.43 0.45 6.45e-19 Corneal astigmatism; LIHC cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.63 0.38 2.39e-13 Bipolar disorder; LIHC cis rs1983891 0.955 rs6917270 chr6:41548755 A/G cg20194872 chr6:41519635 FOXP4 0.42 6.74 0.34 6.66e-11 Prostate cancer; LIHC cis rs9918079 0.506 rs10214 chr4:15606431 T/C cg24225360 chr4:15471699 CC2D2A 0.4 6.46 0.33 3.56e-10 Obesity-related traits; LIHC cis rs950169 0.881 rs150965 chr15:85080527 T/G cg12863693 chr15:85201151 NMB 0.44 6.14 0.32 2.24e-9 Schizophrenia; LIHC cis rs35306767 0.903 rs12762228 chr10:880854 G/A cg20503657 chr10:835505 NA 1.35 14.76 0.62 1.75e-38 Eosinophil percentage of granulocytes; LIHC cis rs727505 1.000 rs7806680 chr7:124433079 G/A cg23710748 chr7:124431027 NA -0.34 -6.06 -0.31 3.56e-9 Lewy body disease; LIHC cis rs8108269 0.956 rs10420680 chr19:46158828 A/G cg13320842 chr19:46175254 GIPR 0.41 7.7 0.38 1.5e-13 Type 2 diabetes; LIHC cis rs3806843 0.868 rs2563291 chr5:140119599 T/A cg19875535 chr5:140030758 IK -0.37 -6.1 -0.31 2.86e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs8062405 0.688 rs3924376 chr16:28925978 T/C cg00204512 chr16:28754710 NA -0.37 -6.5 -0.33 2.89e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs943466 1.000 rs6933568 chr6:33751261 G/A cg25922239 chr6:33757077 LEMD2 -0.48 -5.81 -0.3 1.45e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs4474465 0.850 rs4590904 chr11:78263847 C/T cg27205649 chr11:78285834 NARS2 0.39 5.87 0.3 1.04e-8 Alzheimer's disease (survival time); LIHC cis rs2841277 0.708 rs10083374 chr14:105402994 T/C cg15352829 chr14:105391018 PLD4 -0.43 -9.22 -0.45 3.04e-18 Rheumatoid arthritis; LIHC cis rs4319547 0.956 rs10847179 chr12:123040985 T/C cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.15 -0.4 6.97e-15 Body mass index; LIHC trans rs1005277 0.522 rs289650 chr10:37975505 G/T cg17830980 chr10:43048298 ZNF37B -0.38 -7.57 -0.38 3.42e-13 Extrinsic epigenetic age acceleration; LIHC cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg06634786 chr22:41940651 POLR3H 0.8 9.02 0.44 1.43e-17 Vitiligo; LIHC cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg03806693 chr22:41940476 POLR3H -1.08 -12.5 -0.56 8.97e-30 Vitiligo; LIHC cis rs6762477 0.748 rs11717349 chr3:50223977 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.51 -7.11 -0.36 6.66e-12 Menarche (age at onset); LIHC cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC cis rs7520050 1.000 rs12143096 chr1:46469763 G/A cg03146154 chr1:46216737 IPP -0.38 -6.21 -0.32 1.5e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10857712 0.754 rs1052582 chr10:135233840 C/G cg19623624 chr10:135278901 LOC619207 -0.45 -6.98 -0.35 1.53e-11 Systemic lupus erythematosus; LIHC cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg07092213 chr7:1199455 ZFAND2A -0.44 -6.42 -0.33 4.65e-10 Longevity;Endometriosis; LIHC cis rs2108225 0.714 rs10953548 chr7:107436232 G/A cg18560240 chr7:107437656 SLC26A3 -0.51 -8.04 -0.4 1.46e-14 Ulcerative colitis; LIHC cis rs9457247 1.000 rs409356 chr6:167405226 T/A cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs7909074 0.966 rs879074 chr10:45400053 G/A cg04218760 chr10:45406644 TMEM72 -0.21 -6.67 -0.34 1.03e-10 Mean corpuscular volume; LIHC cis rs738321 0.794 rs5756940 chr22:38558842 C/T cg25457927 chr22:38595422 NA -0.35 -7.78 -0.39 8.79e-14 Breast cancer; LIHC cis rs34779708 0.897 rs7897827 chr10:35386237 C/T cg04310649 chr10:35416472 CREM -0.44 -5.94 -0.31 7.05e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1023500 1.000 rs9620001 chr22:42330229 T/C cg04733989 chr22:42467013 NAGA -0.53 -6.18 -0.32 1.84e-9 Schizophrenia; LIHC cis rs250677 0.522 rs6875902 chr5:148407893 C/A cg18129178 chr5:148520854 ABLIM3 -0.49 -5.85 -0.3 1.15e-8 Breast cancer; LIHC cis rs9640161 0.789 rs13223702 chr7:150058968 G/A cg17279839 chr7:150038598 RARRES2 0.48 8.99 0.44 1.77e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs11583043 0.918 rs56402739 chr1:101397133 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.42 0.41 1.05e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs11893307 0.507 rs1465305 chr2:191585392 C/G cg10560079 chr2:191398806 TMEM194B -0.42 -6.08 -0.31 3.28e-9 Mean platelet volume; LIHC trans rs10506458 1.000 rs12425655 chr12:63434463 C/T cg22491629 chr6:157744540 C6orf35 -0.59 -10.46 -0.49 2.08e-22 Hemostatic factors and hematological phenotypes; LIHC trans rs2243480 1.000 rs7778911 chr7:65694506 T/C cg10756647 chr7:56101905 PSPH -1.04 -12.56 -0.56 5.34e-30 Diabetic kidney disease; LIHC cis rs77741769 0.571 rs3883901 chr12:121256520 A/G cg02419362 chr12:121203948 SPPL3 0.34 5.93 0.31 7.36e-9 Mean corpuscular volume; LIHC cis rs8044995 0.563 rs73615919 chr16:68398862 C/T cg03983715 chr16:68378420 PRMT7 -0.48 -5.81 -0.3 1.47e-8 Schizophrenia; LIHC cis rs651907 0.535 rs2290859 chr3:101525625 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.65 10.75 0.5 2.13e-23 Colorectal cancer; LIHC cis rs11785400 1.000 rs4557682 chr8:143738182 T/C cg24634471 chr8:143751801 JRK 0.52 8.36 0.41 1.55e-15 Schizophrenia; LIHC cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg02931644 chr1:25747376 RHCE 0.35 7.6 0.38 2.88e-13 Plateletcrit;Mean corpuscular volume; LIHC cis rs6835098 0.924 rs7672108 chr4:174165126 A/G cg27433088 chr4:174089019 GALNT7 -0.4 -6.87 -0.35 2.98e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs892961 0.932 rs7223768 chr17:75410521 G/A cg05865280 chr17:75406074 SEPT9 0.6 11.19 0.52 5.57e-25 Airflow obstruction; LIHC cis rs9871864 0.868 rs9820730 chr3:20348723 A/G cg00235661 chr3:20228976 SGOL1 -0.31 -5.87 -0.3 1.06e-8 Behavioural disinhibition (generation interaction); LIHC cis rs11864453 0.578 rs2072141 chr16:72133211 G/A cg01557791 chr16:72042693 DHODH -0.45 -7.52 -0.38 4.95e-13 Fibrinogen levels; LIHC cis rs506338 0.517 rs516117 chr11:64433444 T/C cg03263716 chr11:64435066 NRXN2 0.35 7.61 0.38 2.72e-13 Body mass index;Urate levels; LIHC trans rs10761482 0.564 rs10733765 chr10:62237399 T/C cg17314160 chr12:110399253 GIT2 -0.42 -6.21 -0.32 1.56e-9 Schizophrenia; LIHC cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg12292205 chr6:26970375 C6orf41 -0.48 -8.24 -0.41 3.61e-15 Autism spectrum disorder or schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26820641 chr20:30326728 TPX2 0.43 6.24 0.32 1.31e-9 Cognitive function; LIHC cis rs6430585 0.528 rs6430594 chr2:136719173 C/T cg25344623 chr2:136566232 LCT 0.36 5.86 0.3 1.06e-8 Corneal structure; LIHC cis rs2274273 0.745 rs8005399 chr14:55542845 A/G cg01864836 chr14:55583639 NA -0.37 -6.34 -0.32 7.3e-10 Protein biomarker; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02667081 chr16:71880439 ATXN1L 0.39 6.05 0.31 3.74e-9 Cognitive function; LIHC cis rs1843834 0.539 rs2068244 chr2:225440011 A/G cg12698349 chr2:225449008 CUL3 -0.61 -9.03 -0.44 1.29e-17 IgE levels in asthmatics (D.p. specific); LIHC cis rs11122272 0.732 rs999010 chr1:231495316 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -11.3 -0.52 2.25e-25 Hemoglobin concentration; LIHC cis rs9368481 0.645 rs10456350 chr6:26975581 A/C cg18867708 chr6:26865862 GUSBL1 0.56 8.65 0.42 2.1e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg03517284 chr6:25882590 NA -0.62 -8.91 -0.43 3.13e-17 Blood metabolite levels; LIHC cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg17971929 chr21:40555470 PSMG1 -0.39 -6.04 -0.31 4.02e-9 Menarche (age at onset); LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs1046896 0.739 rs2379358 chr17:80741612 G/A cg22027946 chr17:80790580 TBCD;ZNF750 0.41 5.75 0.3 1.95e-8 Glycated hemoglobin levels; LIHC cis rs7945718 0.621 rs10831894 chr11:12680733 G/A cg25843174 chr11:12811716 TEAD1 0.34 7.87 0.39 4.59e-14 Educational attainment (years of education); LIHC cis rs36051895 0.589 rs6476945 chr9:5191793 C/T cg02405213 chr9:5042618 JAK2 -0.69 -11.64 -0.53 1.32e-26 Pediatric autoimmune diseases; LIHC cis rs12711979 0.765 rs10208316 chr2:3827630 T/C cg17052675 chr2:3827356 NA -0.44 -7.67 -0.38 1.77e-13 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs2576037 0.583 rs2576050 chr18:44558912 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.73 -11.4 -0.52 9.58e-26 Personality dimensions; LIHC cis rs8114671 0.662 rs3761143 chr20:33545745 C/T cg07148914 chr20:33460835 GGT7 0.64 9.92 0.47 1.51e-20 Height; LIHC cis rs861318 0.646 rs2518555 chr1:159012535 A/G cg11003133 chr1:159046391 AIM2 0.34 6.77 0.34 5.5e-11 Obesity-related traits; LIHC cis rs9733 0.596 rs72702556 chr1:150680115 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs6500602 0.702 rs11076835 chr16:4549618 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.44 6.3 0.32 9.35e-10 Schizophrenia; LIHC cis rs3812111 0.647 rs1546943 chr6:116501503 G/A cg08036074 chr6:116424633 NT5DC1 -0.54 -9.09 -0.44 8.47e-18 Age-related macular degeneration; LIHC cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg23758822 chr17:41437982 NA 0.91 16.91 0.67 4.8e-47 Menopause (age at onset); LIHC cis rs9790314 0.690 rs6783085 chr3:160830929 A/G cg03342759 chr3:160939853 NMD3 -0.72 -11.09 -0.51 1.25e-24 Morning vs. evening chronotype; LIHC cis rs6570726 0.902 rs9390326 chr6:145791222 A/G cg23711669 chr6:146136114 FBXO30 -0.46 -7.83 -0.39 6.03e-14 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06443542 chr10:100206752 HPS1 -0.41 -6.41 -0.33 4.78e-10 Pancreatic cancer; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg01516881 chr6:292596 DUSP22 -0.56 -7.58 -0.38 3.23e-13 Menopause (age at onset); LIHC cis rs1008375 0.864 rs4698196 chr4:17574735 T/C cg16339924 chr4:17578868 LAP3 0.56 7.2 0.36 3.96e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg08822215 chr16:89438651 ANKRD11 -0.4 -6.3 -0.32 9.31e-10 Multiple myeloma (IgH translocation); LIHC cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.78 7.76 0.39 1.02e-13 Platelet count; LIHC cis rs35883536 1.000 rs12724990 chr1:101137030 G/A cg14515779 chr1:101123966 NA -0.7 -14.03 -0.6 1.21e-35 Monocyte count; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg26149108 chr5:65275261 ERBB2IP -0.39 -7.35 -0.37 1.48e-12 Calcium levels; LIHC cis rs7395581 0.775 rs2269434 chr11:47360412 T/C cg25783544 chr11:47291846 MADD 0.41 5.92 0.3 7.85e-9 HDL cholesterol; LIHC cis rs477692 0.905 rs524545 chr10:131411840 A/C cg19680672 chr10:131412579 MGMT 0.43 6.69 0.34 9.13e-11 Response to temozolomide; LIHC cis rs208520 0.690 rs12202913 chr6:66734198 C/T cg07460842 chr6:66804631 NA 0.79 9.18 0.44 4.09e-18 Exhaled nitric oxide output; LIHC cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg19318889 chr4:1322082 MAEA 0.46 6.49 0.33 3.11e-10 Obesity-related traits; LIHC cis rs1728785 1.000 rs1728764 chr16:68572292 G/C cg02972257 chr16:68554789 NA -0.56 -6.45 -0.33 3.89e-10 Ulcerative colitis; LIHC cis rs8060686 0.641 rs9932251 chr16:68131732 G/A cg05110241 chr16:68378359 PRMT7 -0.57 -6.61 -0.34 1.48e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs8017423 0.935 rs8012303 chr14:90715829 G/A cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 3.09e-9 Mortality in heart failure; LIHC cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg18305652 chr10:134549665 INPP5A 0.43 6.31 0.32 8.4e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10979 1.000 rs9496671 chr6:143884742 G/A cg25407410 chr6:143891975 LOC285740 -0.39 -6.21 -0.32 1.55e-9 Hypospadias; LIHC cis rs67478160 0.619 rs3742365 chr14:104198251 A/G cg08213375 chr14:104286397 PPP1R13B 0.58 11.02 0.51 2.21e-24 Schizophrenia; LIHC trans rs561341 0.941 rs17780086 chr17:30343282 G/A cg20587970 chr11:113659929 NA -1.45 -12.12 -0.55 2.26e-28 Hip circumference adjusted for BMI; LIHC cis rs6728642 0.908 rs10207116 chr2:98018281 G/A cg26665480 chr2:98280029 ACTR1B -0.65 -6.4 -0.33 5.26e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs7927592 0.913 rs12284933 chr11:68319489 G/A cg16797656 chr11:68205561 LRP5 0.51 8.04 0.4 1.47e-14 Total body bone mineral density; LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg11494091 chr17:61959527 GH2 0.34 5.77 0.3 1.82e-8 Height; LIHC trans rs1005277 0.505 rs13503 chr10:38239843 C/A cg27523141 chr10:43048294 ZNF37B -0.39 -6.79 -0.34 4.84e-11 Extrinsic epigenetic age acceleration; LIHC cis rs4332037 0.901 rs7791299 chr7:1935598 T/C cg23422044 chr7:1970798 MAD1L1 -0.57 -6.9 -0.35 2.54e-11 Bipolar disorder; LIHC cis rs72781680 0.611 rs2111884 chr2:24289472 A/T cg06627628 chr2:24431161 ITSN2 -0.64 -7.37 -0.37 1.32e-12 Lymphocyte counts; LIHC cis rs4820539 0.641 rs5759602 chr22:23489362 C/T cg14186256 chr22:23484241 RTDR1 -0.83 -9.87 -0.47 2.22e-20 Bone mineral density; LIHC cis rs2153535 0.580 rs9406172 chr6:8515464 T/A cg21535247 chr6:8435926 SLC35B3 0.63 8.22 0.41 4.32e-15 Motion sickness; LIHC cis rs11676855 0.927 rs4341884 chr2:235918504 G/T cg14917874 chr2:235941519 SH3BP4 0.51 7.07 0.36 8.75e-12 Dialysis-related mortality; LIHC cis rs875971 0.737 rs7803424 chr7:65880605 T/C cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs10792665 0.575 rs10736757 chr11:82560858 A/G cg24227371 chr11:82718527 RAB30 -0.26 -6.24 -0.32 1.28e-9 Obesity-related traits; LIHC trans rs11098499 0.779 rs7674500 chr4:120303593 C/T cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs1494950 1.000 rs7661362 chr4:15077742 T/A cg12377275 chr4:15005593 CPEB2 -0.88 -7.56 -0.38 3.77e-13 Political ideology; LIHC trans rs1814175 0.500 rs1825677 chr11:49233099 T/G cg15704280 chr7:45808275 SEPT13 -0.61 -9.85 -0.47 2.65e-20 Height; LIHC cis rs1005277 0.579 rs2800485 chr10:38542588 G/A cg17219203 chr10:38645113 HSD17B7P2 -0.39 -5.72 -0.3 2.34e-8 Extrinsic epigenetic age acceleration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07867325 chr3:73159953 NA -0.3 -6.07 -0.31 3.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs1215050 0.791 rs968854 chr4:98837863 T/C cg05340658 chr4:99064831 C4orf37 0.39 5.77 0.3 1.74e-8 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs59072263 0.850 rs55916403 chr7:8144051 T/A cg21324884 chr3:64801329 MIR548A2 0.74 6.12 0.31 2.53e-9 Intraocular pressure; LIHC cis rs870825 0.616 rs6844146 chr4:185636396 G/A cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC cis rs244293 0.760 rs12945393 chr17:53045243 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.45 -6.45 -0.33 3.89e-10 Menarche (age at onset); LIHC cis rs6840360 1.000 rs10049991 chr4:152664163 A/T cg22705602 chr4:152727874 NA -0.34 -7.01 -0.35 1.27e-11 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg22528358 chr1:107598549 PRMT6 -0.65 -10.64 -0.5 4.93e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9549367 0.789 rs71446679 chr13:113894821 C/T cg00898013 chr13:113819073 PROZ -0.42 -7.35 -0.37 1.46e-12 Platelet distribution width; LIHC cis rs9733 0.596 rs12077833 chr1:150674333 C/T cg17724175 chr1:150552817 MCL1 0.48 9.74 0.47 6.17e-20 Tonsillectomy; LIHC trans rs1005277 0.579 rs9299760 chr10:38377920 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs3749237 0.595 rs4855859 chr3:49526300 C/T cg06212747 chr3:49208901 KLHDC8B 0.46 6.01 0.31 4.66e-9 Resting heart rate; LIHC cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg02187348 chr16:89574699 SPG7 0.64 10.21 0.48 1.51e-21 Multiple myeloma (IgH translocation); LIHC cis rs3858526 0.727 rs10769353 chr11:5954809 C/T cg13902645 chr11:5959945 NA 0.3 6.94 0.35 1.99e-11 DNA methylation (variation); LIHC cis rs6582630 0.537 rs3942440 chr12:38459672 A/G cg26384229 chr12:38710491 ALG10B 0.66 9.14 0.44 5.63e-18 Drug-induced liver injury (flucloxacillin); LIHC cis rs35883536 0.647 rs1995142 chr1:101041174 G/A cg14515779 chr1:101123966 NA -0.45 -6.38 -0.33 5.67e-10 Monocyte count; LIHC cis rs12048904 0.595 rs10493937 chr1:101342650 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.83 -14.24 -0.61 1.88e-36 Multiple sclerosis; LIHC cis rs11676348 0.808 rs4674261 chr2:219005009 G/C cg00012203 chr2:219082015 ARPC2 -0.47 -6.1 -0.31 2.81e-9 Ulcerative colitis; LIHC cis rs916888 0.821 rs199506 chr17:44859031 A/G cg01570182 chr17:44337453 NA -0.96 -9.61 -0.46 1.6e-19 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg24209194 chr3:40518798 ZNF619 0.43 6.09 0.31 2.97e-9 Renal cell carcinoma; LIHC cis rs240764 0.817 rs239242 chr6:101092776 C/T cg09795085 chr6:101329169 ASCC3 0.51 7.12 0.36 6.46e-12 Neuroticism; LIHC cis rs35110281 0.748 rs2838322 chr21:44998615 G/C cg01579765 chr21:45077557 HSF2BP -0.38 -7.09 -0.36 7.59e-12 Mean corpuscular volume; LIHC cis rs921968 0.643 rs2243911 chr2:219529348 C/T cg18887096 chr2:219472410 PLCD4 -0.39 -6.69 -0.34 9.17e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9486719 0.843 rs976357 chr6:96849679 C/T cg06623918 chr6:96969491 KIAA0776 0.71 6.87 0.35 2.96e-11 Migraine;Coronary artery disease; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg03395511 chr6:291903 DUSP22 -0.48 -6.3 -0.32 8.94e-10 Menopause (age at onset); LIHC cis rs17826219 0.561 rs562840 chr17:28949390 G/T cg13385521 chr17:29058706 SUZ12P 0.58 5.85 0.3 1.13e-8 Body mass index; LIHC cis rs7945705 0.774 rs6486060 chr11:9024630 A/G cg12365402 chr11:9010492 NRIP3 0.27 6.78 0.34 5.16e-11 Hemoglobin concentration; LIHC cis rs3790645 1.000 rs1064196 chr1:26887592 C/T cg17456097 chr1:26900765 RPS6KA1 -0.4 -5.85 -0.3 1.13e-8 Glucose homeostasis traits; LIHC cis rs758324 0.947 rs687816 chr5:131262077 C/T cg06307176 chr5:131281290 NA -0.4 -5.82 -0.3 1.33e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs12594515 1.000 rs7173144 chr15:45991196 A/G cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC trans rs11722228 0.522 rs2241468 chr4:10113905 G/A cg26043149 chr18:55253948 FECH 0.97 13.74 0.6 1.66e-34 Gout;Urate levels;Serum uric acid levels; LIHC cis rs9911578 1.000 rs12602346 chr17:56901713 T/C cg12560992 chr17:57184187 TRIM37 0.96 17.37 0.68 6.51e-49 Intelligence (multi-trait analysis); LIHC cis rs360798 0.532 rs7573756 chr2:62990637 G/A cg17519650 chr2:63277830 OTX1 -0.54 -8.29 -0.41 2.56e-15 Coronary artery disease; LIHC cis rs9583531 0.600 rs3809344 chr13:111358705 G/A cg24331049 chr13:111365604 ING1 0.78 13.07 0.58 6.31e-32 Coronary artery disease; LIHC cis rs4788570 0.697 rs9930015 chr16:71801092 C/G cg06353428 chr16:71660113 MARVELD3 1.22 13.1 0.58 4.55e-32 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.721 rs12037803 chr1:46156492 A/G cg06784218 chr1:46089804 CCDC17 0.42 7.74 0.39 1.11e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11888559 0.655 rs12615537 chr2:204005715 T/A cg24605529 chr2:203879461 NBEAL1 0.78 5.92 0.31 7.62e-9 Height; LIHC cis rs11122272 0.735 rs11122279 chr1:231519804 A/G cg06096015 chr1:231504339 EGLN1 0.48 8.71 0.43 1.34e-16 Hemoglobin concentration; LIHC cis rs7116495 1.000 rs658661 chr11:71559269 T/G cg26138937 chr11:71823887 C11orf51 0.67 6.43 0.33 4.3e-10 Severe influenza A (H1N1) infection; LIHC cis rs10508774 1.000 rs35949115 chr10:33054173 G/A cg01819863 chr10:32635814 EPC1 0.63 5.78 0.3 1.68e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2637266 1.000 rs11001835 chr10:78364770 A/G cg18941641 chr10:78392320 NA 0.3 6.5 0.33 2.92e-10 Pulmonary function; LIHC trans rs875971 0.545 rs66594357 chr7:65792784 G/A cg26939375 chr7:64535504 NA 0.41 6.48 0.33 3.18e-10 Aortic root size; LIHC cis rs5769707 0.605 rs9616702 chr22:50025938 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.29 -0.41 2.55e-15 Monocyte count;Monocyte percentage of white cells; LIHC trans rs11098499 0.863 rs12502389 chr4:120454191 A/G cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC trans rs8002861 0.935 rs7318147 chr13:44445153 C/G cg00199846 chr13:37393246 RFXAP 0.45 6.16 0.32 2e-9 Leprosy; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg06873352 chr17:61820015 STRADA 0.73 12.98 0.57 1.31e-31 Prudent dietary pattern; LIHC cis rs986417 1.000 rs1033733 chr14:60932438 G/T cg27398547 chr14:60952738 C14orf39 0.73 8.41 0.41 1.1e-15 Gut microbiota (bacterial taxa); LIHC cis rs67311347 0.577 rs11712626 chr3:40259927 G/A cg13409248 chr3:40428643 ENTPD3 0.41 6.41 0.33 4.79e-10 Renal cell carcinoma; LIHC trans rs12478296 1.000 rs73007129 chr2:243000555 T/C cg01596870 chr19:55963115 NA -0.6 -7.01 -0.35 1.25e-11 Obesity-related traits; LIHC cis rs1534166 0.647 rs13321680 chr3:133507119 G/T cg12373951 chr3:133503437 NA -0.48 -6.8 -0.35 4.65e-11 Alcohol consumption (transferrin glycosylation); LIHC trans rs2235573 0.551 rs139898 chr22:38399979 A/G cg19894588 chr14:64061835 NA 0.48 6.51 0.33 2.69e-10 Glioblastoma;Glioma; LIHC cis rs7412746 0.611 rs10888398 chr1:150886782 A/G cg17724175 chr1:150552817 MCL1 -0.38 -7.34 -0.37 1.59e-12 Melanoma; LIHC cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.67 11.37 0.52 1.3e-25 Menarche (age at onset); LIHC cis rs898097 0.841 rs4986122 chr17:80825500 C/T cg15369054 chr17:80825471 TBCD 0.44 6.36 0.33 6.28e-10 Breast cancer; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg00280220 chr17:61926910 NA 0.42 6.89 0.35 2.73e-11 Prudent dietary pattern; LIHC cis rs8027181 0.839 rs9460 chr15:73044575 C/T cg25632853 chr15:73088954 NA 0.36 6.02 0.31 4.47e-9 Triglyceride levels; LIHC cis rs12477438 1.000 rs6542873 chr2:99824965 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -8.32 -0.41 2.17e-15 Chronic sinus infection; LIHC cis rs11122272 0.735 rs2244994 chr1:231537127 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.75e-22 Hemoglobin concentration; LIHC cis rs7264396 0.790 rs6060530 chr20:34227663 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -9.94 -0.47 1.23e-20 Total cholesterol levels; LIHC cis rs992157 0.965 rs13427681 chr2:219167563 G/C cg20019365 chr2:219134978 PNKD;AAMP 0.82 13.38 0.59 3.95e-33 Colorectal cancer; LIHC cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.52 -7.33 -0.37 1.63e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs13191362 0.935 rs7769048 chr6:163010040 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs909002 0.849 rs1464306 chr1:32076261 T/C cg13919466 chr1:32135498 COL16A1 -0.31 -6.17 -0.32 1.92e-9 Intelligence (multi-trait analysis); LIHC cis rs17376456 0.690 rs6892055 chr5:93113023 A/T cg25358565 chr5:93447407 FAM172A 1.04 9.51 0.46 3.49e-19 Diabetic retinopathy; LIHC cis rs922107 0.967 rs1885746 chr1:90015719 A/C cg15422784 chr1:90023713 LRRC8B -0.47 -7.71 -0.38 1.4e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7872515 0.775 rs7024583 chr9:94824750 C/T cg01248375 chr9:94877805 SPTLC1 0.53 7.55 0.38 4.1e-13 Bipolar disorder and schizophrenia; LIHC cis rs1577917 0.727 rs9444361 chr6:86400900 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.48 8.06 0.4 1.27e-14 Response to antipsychotic treatment; LIHC cis rs4788570 0.615 rs1058750 chr16:71679057 C/T cg06353428 chr16:71660113 MARVELD3 1.45 15.6 0.64 8.48e-42 Intelligence (multi-trait analysis); LIHC cis rs2386661 0.547 rs11259582 chr10:5646767 C/T cg17085576 chr10:5658249 NA -0.35 -6.2 -0.32 1.66e-9 Breast cancer; LIHC cis rs4919694 1.000 rs11191439 chr10:104638723 C/T cg04362960 chr10:104952993 NT5C2 -1.0 -8.17 -0.4 6.1e-15 Arsenic metabolism; LIHC cis rs1144333 1.000 rs12082448 chr1:76353225 C/T cg10523679 chr1:76189770 ACADM 0.47 6.73 0.34 7.29e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs2997447 0.637 rs2000403 chr1:26410161 A/G cg19633962 chr1:26362018 EXTL1 -0.7 -6.4 -0.33 5.06e-10 QRS complex (12-leadsum); LIHC trans rs17685 0.671 rs10274404 chr7:75706634 G/A cg19862616 chr7:65841803 NCRNA00174 0.93 19.32 0.72 9.83e-57 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35306767 0.903 rs10904577 chr10:922077 A/G cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.13 -0.31 2.49e-9 Total body bone mineral density; LIHC cis rs6840360 0.571 rs4696100 chr4:152514242 C/T cg22705602 chr4:152727874 NA -0.32 -6.22 -0.32 1.43e-9 Intelligence (multi-trait analysis); LIHC cis rs7144547 0.950 rs8004137 chr14:81884857 A/G cg02996355 chr14:81879375 NA -0.88 -14.15 -0.61 4.17e-36 Prudent dietary pattern; LIHC cis rs6570726 0.791 rs1509214 chr6:145784606 A/C cg23711669 chr6:146136114 FBXO30 -0.68 -10.64 -0.5 4.94e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs1577917 0.655 rs9450311 chr6:86376586 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.59 0.42 3.17e-16 Response to antipsychotic treatment; LIHC cis rs10792665 0.844 rs10751084 chr11:82682918 C/G cg24227371 chr11:82718527 RAB30 -0.32 -7.58 -0.38 3.31e-13 Obesity-related traits; LIHC cis rs11603020 0.950 rs28362951 chr11:57372526 A/G cg19752551 chr11:57585705 CTNND1 -0.46 -5.88 -0.3 9.93e-9 Blood protein levels; LIHC trans rs1814175 0.645 rs28447324 chr11:50046629 C/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs473651 0.904 rs62196716 chr2:239356977 C/G cg21699342 chr2:239360505 ASB1 0.37 7.16 0.36 5e-12 Multiple system atrophy; LIHC trans rs17473412 0.677 rs7703751 chr5:122831981 A/T cg04915494 chr16:2962968 FLYWCH1 -0.47 -6.2 -0.32 1.66e-9 Total body bone mineral density; LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg08280861 chr8:58055591 NA 0.51 6.38 0.33 5.8e-10 Developmental language disorder (linguistic errors); LIHC cis rs61990749 0.544 rs2544567 chr14:78181739 T/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.81 -0.39 6.91e-14 Fibroblast growth factor basic levels; LIHC cis rs1144333 0.655 rs76175698 chr1:76454792 C/T cg22875332 chr1:76189707 ACADM 0.4 5.93 0.31 7.52e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2963155 0.518 rs864355 chr5:142633229 A/G cg17617527 chr5:142782415 NR3C1 0.94 10.37 0.49 4.19e-22 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01074676 chr14:60601069 C14orf135 -0.33 -6.24 -0.32 1.29e-9 Lung function (FEV1/FVC); LIHC cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg16497277 chr3:49208875 KLHDC8B -0.51 -6.36 -0.33 6.61e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs2286885 1.000 rs10733677 chr9:129242209 A/G cg15282417 chr9:129245246 FAM125B 0.42 6.96 0.35 1.71e-11 Intraocular pressure; LIHC cis rs4803468 0.967 rs7259900 chr19:41889429 A/T cg09537434 chr19:41945824 ATP5SL -1.0 -20.31 -0.74 9.9e-61 Height; LIHC trans rs12478296 0.786 rs55876934 chr2:243033816 C/T cg01596870 chr19:55963115 NA -0.63 -8.42 -0.41 1.08e-15 Obesity-related traits; LIHC cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.11 -0.36 6.93e-12 Diabetic kidney disease; LIHC cis rs8141529 0.748 rs132529 chr22:29296652 A/G cg15103426 chr22:29168792 CCDC117 -0.56 -8.88 -0.43 3.96e-17 Lymphocyte counts; LIHC cis rs12701220 0.520 rs7803208 chr7:1162084 C/T cg00990874 chr7:1149470 C7orf50 -0.39 -5.91 -0.3 8.46e-9 Bronchopulmonary dysplasia; LIHC cis rs8180040 0.966 rs6790763 chr3:47572585 C/A cg16586182 chr3:47516702 SCAP -0.43 -7.47 -0.37 6.74e-13 Colorectal cancer; LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs546131 0.642 rs523246 chr11:34845011 C/G cg11058730 chr11:34937778 PDHX;APIP 0.64 9.46 0.46 5.25e-19 Lung disease severity in cystic fibrosis; LIHC cis rs4700695 0.841 rs251306 chr5:65252453 C/T cg21114390 chr5:65439923 SFRS12 0.44 5.77 0.3 1.8e-8 Facial morphology (factor 19); LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg03785755 chr6:26196794 NA 0.51 5.97 0.31 5.8e-9 Gout;Renal underexcretion gout; LIHC cis rs34779708 0.966 rs12765038 chr10:35416513 G/C cg04310649 chr10:35416472 CREM -0.45 -6.08 -0.31 3.17e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3793683 0.825 rs3793674 chr10:134555773 C/T cg18305652 chr10:134549665 INPP5A -0.39 -6.45 -0.33 3.79e-10 Migraine; LIHC trans rs2235573 0.527 rs139865 chr22:38353932 C/G cg19894588 chr14:64061835 NA 0.48 6.41 0.33 4.9e-10 Glioblastoma;Glioma; LIHC cis rs7264396 0.563 rs6060592 chr20:34352414 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.55 -7.64 -0.38 2.14e-13 Total cholesterol levels; LIHC cis rs1577917 0.666 rs6454471 chr6:86214456 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.47 8.33 0.41 2.01e-15 Response to antipsychotic treatment; LIHC cis rs2112347 0.502 rs34339 chr5:74931333 G/T cg07671805 chr5:74907694 NA -0.52 -6.16 -0.32 2.02e-9 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs921968 0.613 rs2303566 chr2:219557738 C/T cg02985541 chr2:219472218 PLCD4 -0.39 -6.61 -0.34 1.46e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03685910 chr17:39844834 EIF1 0.36 6.03 0.31 4.17e-9 Cognitive function; LIHC cis rs60871478 0.786 rs62432898 chr7:826102 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.52 6.02 0.31 4.48e-9 Cerebrospinal P-tau181p levels; LIHC trans rs6489882 0.867 rs4766676 chr12:113365581 A/G cg10175203 chr3:128143634 NA -0.39 -6.22 -0.32 1.44e-9 Chronic lymphocytic leukemia; LIHC cis rs2637266 1.000 rs7475638 chr10:78358586 G/T cg18941641 chr10:78392320 NA -0.28 -5.96 -0.31 6.11e-9 Pulmonary function; LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.34 0.32 7.32e-10 Total body bone mineral density; LIHC cis rs28374715 0.617 rs28626792 chr15:41562218 A/G cg18705301 chr15:41695430 NDUFAF1 -0.39 -5.74 -0.3 2.04e-8 Ulcerative colitis; LIHC cis rs763121 0.853 rs1056610 chr22:39080078 C/T cg14440974 chr22:39074834 NA 0.37 6.24 0.32 1.29e-9 Menopause (age at onset); LIHC cis rs1865760 0.516 rs9358903 chr6:26061949 A/C cg17691542 chr6:26056736 HIST1H1C 0.45 6.44 0.33 3.97e-10 Height; LIHC cis rs10892173 0.566 rs12364667 chr11:117675286 A/C cg21640587 chr11:117668038 DSCAML1 0.52 6.81 0.35 4.3e-11 Myopia; LIHC cis rs716804 0.740 rs4442543 chr11:10306774 C/T cg01453529 chr11:10209919 SBF2 -0.29 -5.84 -0.3 1.25e-8 Neuroticism; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24182963 chr17:48350615 TMEM92 -0.48 -6.13 -0.31 2.49e-9 Systolic blood pressure; LIHC cis rs7131987 0.874 rs10843366 chr12:29407903 T/C cg16970926 chr12:29381810 FAR2 0.29 6.1 0.31 2.81e-9 QT interval; LIHC cis rs8192917 0.623 rs2273843 chr14:25103409 T/C cg08766149 chr14:25103301 GZMB 0.33 5.95 0.31 6.69e-9 Vitiligo; LIHC trans rs561341 1.000 rs8069199 chr17:30281845 A/G cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 8.04e-24 Hip circumference adjusted for BMI; LIHC cis rs68170813 0.559 rs17427123 chr7:106823661 G/A cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC trans rs9951602 0.512 rs8098115 chr18:76653986 G/T cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs4144743 1.000 rs7223003 chr17:45324293 G/A cg18085866 chr17:45331354 ITGB3 -0.59 -8.53 -0.42 4.87e-16 Body mass index; LIHC cis rs910316 0.737 rs175084 chr14:75519175 C/T cg08847533 chr14:75593920 NEK9 -0.89 -18.35 -0.7 7.62e-53 Height; LIHC cis rs7412746 0.658 rs2275235 chr1:150730279 A/G cg17724175 chr1:150552817 MCL1 0.48 9.3 0.45 1.65e-18 Melanoma; LIHC cis rs2274273 0.840 rs943590 chr14:55738596 T/C cg01864836 chr14:55583639 NA -0.4 -7.31 -0.37 1.86e-12 Protein biomarker; LIHC cis rs1552244 0.882 rs3755782 chr3:10029305 T/C cg13047869 chr3:10149882 C3orf24 0.43 6.07 0.31 3.49e-9 Alzheimer's disease; LIHC cis rs3862030 0.594 rs7923675 chr10:104235809 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.47 6.82 0.35 4.09e-11 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs116095464 0.558 rs10055993 chr5:264296 A/C cg22496380 chr5:211416 CCDC127 -1.14 -10.75 -0.5 1.99e-23 Breast cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08398855 chr16:89283970 ZNF778 -0.5 -6.06 -0.31 3.64e-9 Systolic blood pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21426974 chr4:140005758 ELF2 0.44 6.45 0.33 3.74e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs28595532 1.000 rs11938970 chr4:119660152 A/G cg21605333 chr4:119757512 SEC24D 0.95 9.63 0.46 1.39e-19 Cannabis dependence symptom count; LIHC cis rs9611565 0.512 rs2050033 chr22:42159229 G/T cg03806693 chr22:41940476 POLR3H 0.98 10.31 0.49 7.06e-22 Vitiligo; LIHC cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg25897951 chr4:1244024 CTBP1;C4orf42 -0.4 -5.82 -0.3 1.33e-8 Longevity; LIHC cis rs68170813 0.559 rs76307631 chr7:107058018 A/G cg02696742 chr7:106810147 HBP1 -0.5 -5.73 -0.3 2.24e-8 Coronary artery disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24335600 chr1:241682994 FH 0.44 6.3 0.32 9.26e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9513627 0.915 rs73556179 chr13:100122009 G/A cg25919922 chr13:100150906 NA -0.8 -7.07 -0.36 8.77e-12 Obesity-related traits; LIHC cis rs7772486 0.754 rs6937661 chr6:146113299 T/C cg23711669 chr6:146136114 FBXO30 -0.76 -13.64 -0.59 3.94e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs1499614 1.000 rs2141924 chr7:66186246 C/T cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC cis rs875971 0.929 rs778692 chr7:65872449 A/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs3812111 0.676 rs6915372 chr6:116475557 T/G cg08036074 chr6:116424633 NT5DC1 -0.49 -8.27 -0.41 3.05e-15 Age-related macular degeneration; LIHC cis rs151997 0.671 rs27281 chr5:50200764 C/T cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC cis rs12142240 0.621 rs13374968 chr1:46843908 T/G cg14993813 chr1:46806288 NSUN4 -0.64 -5.78 -0.3 1.66e-8 Menopause (age at onset); LIHC cis rs8177253 0.931 rs8177256 chr3:133480276 G/T cg12373951 chr3:133503437 NA 0.69 12.44 0.56 1.41e-29 Iron status biomarkers; LIHC trans rs61931739 0.534 rs11053029 chr12:34131766 G/T cg26384229 chr12:38710491 ALG10B 0.52 7.07 0.36 8.54e-12 Morning vs. evening chronotype; LIHC cis rs12950390 0.853 rs4794107 chr17:45843159 T/G cg03474202 chr17:45855739 NA -0.35 -6.07 -0.31 3.43e-9 IgG glycosylation; LIHC cis rs9911578 0.935 rs2567912 chr17:56731270 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.69 0.69 3.56e-50 Intelligence (multi-trait analysis); LIHC cis rs1639906 0.895 rs78469080 chr7:2200729 G/A cg02951883 chr7:2050386 MAD1L1 0.57 7.68 0.38 1.73e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs11603020 0.904 rs4926 chr11:57381989 G/A cg19752551 chr11:57585705 CTNND1 -0.46 -5.98 -0.31 5.62e-9 Blood protein levels; LIHC cis rs7772486 0.754 rs6570703 chr6:145957052 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.64 0.53 1.27e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg18654377 chr3:49208889 KLHDC8B -0.5 -5.96 -0.31 6.24e-9 Menarche (age at onset); LIHC cis rs703842 1.000 rs11172349 chr12:58212528 G/A cg18357645 chr12:58087776 OS9 -0.42 -6.3 -0.32 9.23e-10 Multiple sclerosis; LIHC cis rs10876993 0.890 rs1092472 chr12:58036688 G/T cg15848620 chr12:58087721 OS9 -0.55 -7.52 -0.38 4.99e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs17253792 0.822 rs78522049 chr14:56071203 A/C cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs3862260 0.509 rs7552885 chr1:120164966 C/T cg16322792 chr1:120165303 ZNF697 0.52 9.46 0.46 5.04e-19 Systemic lupus erythematosus; LIHC cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.54 7.02 0.36 1.17e-11 Osteoporosis; LIHC cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg18252515 chr7:66147081 NA -1.3 -17.72 -0.69 2.68e-50 Diabetic kidney disease; LIHC trans rs72829446 0.530 rs59665520 chr17:7383136 C/A cg08566640 chr11:64091735 NA -0.67 -6.13 -0.31 2.36e-9 Androgen levels; LIHC cis rs7716219 0.751 rs4865956 chr5:54882505 T/A cg14753740 chr5:54468940 CDC20B;MIR449C 0.46 6.25 0.32 1.2e-9 Height; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.69 0.8 5.21e-78 Prudent dietary pattern; LIHC cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg15691649 chr6:25882328 NA -0.58 -7.48 -0.37 6.53e-13 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.706 rs2302073 chr17:37457342 A/G cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs17685 0.753 rs10085567 chr7:75734206 A/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.37 -5.96 -0.31 6.36e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11980791 chr9:131084797 COQ4;TRUB2 -0.51 -6.32 -0.32 7.93e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6728642 0.519 rs7589232 chr2:97566148 C/T cg26665480 chr2:98280029 ACTR1B -0.52 -5.81 -0.3 1.45e-8 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs9309711 0.623 rs4641971 chr2:3481857 A/C cg15541040 chr2:3486749 NA 0.43 6.72 0.34 7.81e-11 Neurofibrillary tangles; LIHC cis rs490234 0.756 rs10986849 chr9:128469683 A/G cg14078157 chr9:128172775 NA -0.36 -5.97 -0.31 5.97e-9 Mean arterial pressure; LIHC cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.12 11.22 0.52 4.26e-25 Platelet count; LIHC trans rs8113308 0.810 rs8104121 chr19:52443063 C/T cg14959425 chr7:20447707 ITGB8 -0.48 -6.15 -0.32 2.22e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs9814567 1.000 rs4368544 chr3:134300014 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.15 0.32 2.12e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs17021463 0.966 rs10856908 chr4:95222755 G/T cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.08 -0.44 8.97e-18 Testicular germ cell tumor; LIHC cis rs17685 0.735 rs11763339 chr7:75761541 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1577917 0.696 rs2842617 chr6:86309698 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.46 -9.04 -0.44 1.2e-17 Response to antipsychotic treatment; LIHC cis rs9640161 0.789 rs28439010 chr7:150046276 C/T cg10018233 chr7:150070692 REPIN1 0.52 8.34 0.41 1.89e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs7474896 0.583 rs12783272 chr10:38024885 T/G cg25427524 chr10:38739819 LOC399744 -0.5 -7.29 -0.37 2.16e-12 Obesity (extreme); LIHC cis rs2153535 0.563 rs6942177 chr6:8534460 A/G cg21535247 chr6:8435926 SLC35B3 -0.67 -8.82 -0.43 6.07e-17 Motion sickness; LIHC cis rs8141529 0.748 rs5997412 chr22:29276747 G/A cg02153584 chr22:29168773 CCDC117 0.53 8.2 0.41 4.87e-15 Lymphocyte counts; LIHC cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg25072359 chr17:41440525 NA 0.4 6.28 0.32 1.04e-9 Menopause (age at onset); LIHC cis rs8060686 0.545 rs11043 chr16:68262958 G/A cg05110241 chr16:68378359 PRMT7 -0.56 -6.45 -0.33 3.85e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs6570726 0.738 rs6925594 chr6:145898454 T/C cg23711669 chr6:146136114 FBXO30 0.71 12.2 0.55 1.19e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs7771547 0.573 rs9470274 chr6:36397229 G/A cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Platelet distribution width; LIHC cis rs75920871 0.557 rs11216275 chr11:116975704 T/G cg01368799 chr11:117014884 PAFAH1B2 -0.5 -5.93 -0.31 7.4e-9 Subjective well-being; LIHC cis rs2257205 0.667 rs16943147 chr17:56720752 C/A cg12560992 chr17:57184187 TRIM37 0.7 7.73 0.39 1.22e-13 Pancreatic cancer; LIHC cis rs12249377 0.519 rs35987367 chr10:92591992 C/T cg14313238 chr10:92632228 RPP30 0.38 6.44 0.33 4.14e-10 White matter microstructure (global fractional anisotropy); LIHC cis rs6502050 0.805 rs9915071 chr17:80119138 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg20607798 chr8:58055168 NA 0.64 7.99 0.4 2.03e-14 Developmental language disorder (linguistic errors); LIHC cis rs2354432 0.607 rs6677679 chr1:146803630 C/T cg25205988 chr1:146714368 CHD1L -0.9 -10.85 -0.51 8.86e-24 Mitochondrial DNA levels; LIHC cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC trans rs916888 0.821 rs199514 chr17:44856881 G/A cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg09323728 chr8:95962352 TP53INP1 -0.3 -6.48 -0.33 3.13e-10 Type 2 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26189035 chr5:180661257 TRIM41 -0.37 -6.4 -0.33 5.09e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2617583 0.967 rs2617594 chr5:1448288 A/G cg07151155 chr5:1473589 LPCAT1 -0.4 -6.15 -0.32 2.18e-9 Breast cancer; LIHC cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg03517284 chr6:25882590 NA -0.44 -6.67 -0.34 1.04e-10 Height; LIHC cis rs2204008 0.774 rs11495520 chr12:38060605 T/G cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs546131 0.559 rs12803664 chr11:34851929 G/A cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.51 -0.33 2.63e-10 Lung disease severity in cystic fibrosis; LIHC cis rs11671005 0.735 rs3764532 chr19:58929222 G/A cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs6570726 0.935 rs419854 chr6:145844085 A/C cg23711669 chr6:146136114 FBXO30 0.55 9.93 0.47 1.41e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs910316 0.763 rs175014 chr14:75456927 A/G cg08847533 chr14:75593920 NEK9 -0.87 -17.46 -0.69 3.02e-49 Height; LIHC cis rs2806561 1.000 rs2746553 chr1:23493246 T/C cg19743168 chr1:23544995 NA 0.39 7.37 0.37 1.33e-12 Height; LIHC cis rs7534824 0.625 rs6676834 chr1:101463788 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.74 7.06 0.36 9.28e-12 Refractive astigmatism; LIHC cis rs921968 0.643 rs62191565 chr2:219482017 C/T cg18887096 chr2:219472410 PLCD4 0.36 6.29 0.32 9.51e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs11098499 0.697 rs4560394 chr4:120313435 T/G cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.51e-27 Corneal astigmatism; LIHC cis rs951366 0.617 rs708727 chr1:205767885 G/A cg17178900 chr1:205818956 PM20D1 0.75 11.31 0.52 2.12e-25 Menarche (age at onset); LIHC cis rs798554 0.796 rs2533884 chr7:2836848 T/G cg19717773 chr7:2847554 GNA12 -0.43 -6.7 -0.34 8.71e-11 Height; LIHC cis rs2976388 0.647 rs2082801 chr8:143786461 A/G cg13446199 chr8:143762866 PSCA -0.2 -5.93 -0.31 7.44e-9 Urinary tract infection frequency; LIHC cis rs9818758 0.607 rs34343820 chr3:49309534 C/G cg06212747 chr3:49208901 KLHDC8B -0.68 -5.95 -0.31 6.67e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs9309473 0.797 rs6723247 chr2:73846749 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.84 -0.35 3.61e-11 Metabolite levels; LIHC cis rs79149102 0.579 rs8039433 chr15:75367367 T/C cg15902774 chr15:75289873 SCAMP5 0.4 6.0 0.31 4.97e-9 Lung cancer; LIHC cis rs965469 1.000 rs6051762 chr20:3321590 T/C cg25506879 chr20:3388711 C20orf194 -0.59 -6.67 -0.34 1e-10 IFN-related cytopenia; LIHC cis rs1789 0.872 rs4333182 chr4:15684712 G/A cg16509355 chr4:15471240 CC2D2A -0.45 -6.73 -0.34 7.04e-11 Blood protein levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06350524 chr2:169747178 SPC25 0.51 6.77 0.34 5.56e-11 Lung function (FEV1/FVC); LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg11494091 chr17:61959527 GH2 0.44 7.91 0.39 3.7e-14 Prudent dietary pattern; LIHC cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg13409248 chr3:40428643 ENTPD3 0.41 6.91 0.35 2.41e-11 Renal cell carcinoma; LIHC cis rs5769765 0.817 rs9616212 chr22:50317687 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.76 -9.5 -0.46 3.87e-19 Schizophrenia; LIHC cis rs2030401 0.604 rs2682427 chr12:123656809 C/T cg00376283 chr12:123451042 ABCB9 0.55 8.78 0.43 7.97e-17 Intelligence (multi-trait analysis); LIHC cis rs561341 0.843 rs56389115 chr17:30237308 T/C cg13647721 chr17:30228624 UTP6 0.72 7.19 0.36 4e-12 Hip circumference adjusted for BMI; LIHC cis rs7131987 0.650 rs10843377 chr12:29437053 C/G cg21522988 chr12:29376872 FAR2 -0.26 -5.76 -0.3 1.85e-8 QT interval; LIHC cis rs7833986 0.501 rs17812659 chr8:56889862 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.74 6.91 0.35 2.42e-11 Height; LIHC cis rs7903847 0.642 rs2275089 chr10:99141205 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11212260 0.655 rs11212213 chr11:107286421 A/G cg25435332 chr11:107328525 CWF19L2 0.8 8.47 0.42 7.45e-16 IgG glycosylation; LIHC cis rs743757 1.000 rs2282752 chr3:50433967 G/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.7 0.38 1.45e-13 Diastolic blood pressure; LIHC cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg13393036 chr8:95962371 TP53INP1 -0.45 -11.03 -0.51 2.02e-24 Type 2 diabetes; LIHC cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg03806693 chr22:41940476 POLR3H 1.03 12.62 0.56 3.16e-30 Vitiligo; LIHC cis rs11997175 0.583 rs7829680 chr8:33794207 C/T ch.8.33884649F chr8:33765107 NA -0.32 -6.03 -0.31 4.26e-9 Body mass index; LIHC cis rs6960043 0.584 rs992823 chr7:15041187 C/T cg19272540 chr7:15055459 NA 0.24 6.53 0.33 2.41e-10 Type 2 diabetes; LIHC cis rs10097731 0.901 rs7823749 chr8:82047828 C/A cg25230327 chr8:82042993 NA -0.58 -7.77 -0.39 9.18e-14 Serum total protein level; LIHC cis rs28374715 0.532 rs7164211 chr15:41705041 A/T cg18705301 chr15:41695430 NDUFAF1 -1.23 -19.07 -0.72 9.59e-56 Ulcerative colitis; LIHC cis rs908922 0.676 rs4845782 chr1:152492225 A/G cg23254163 chr1:152506842 NA 0.23 5.83 0.3 1.28e-8 Hair morphology; LIHC cis rs311392 1.000 rs2666871 chr8:55089184 C/T cg11783602 chr8:55087084 NA -0.31 -6.18 -0.32 1.84e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs801193 1.000 rs3857688 chr7:66127806 G/A cg14393609 chr7:65229607 NA -0.37 -5.83 -0.3 1.27e-8 Aortic root size; LIHC cis rs3762637 1.000 rs76599189 chr3:122124076 G/A cg24169773 chr3:122142474 KPNA1 -0.47 -9.18 -0.44 4.16e-18 LDL cholesterol levels; LIHC cis rs1953600 0.645 rs2819950 chr10:81935279 G/A cg27417294 chr10:81904244 PLAC9 -0.36 -6.18 -0.32 1.78e-9 Sarcoidosis; LIHC trans rs7618501 1.000 rs2234391 chr3:49842625 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.79 14.38 0.61 5.17e-37 Intelligence (multi-trait analysis); LIHC cis rs7914558 0.621 rs10786722 chr10:104660068 C/T cg15744005 chr10:104629667 AS3MT -0.35 -7.2 -0.36 3.87e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.88 0.3 9.86e-9 Menopause (age at onset); LIHC cis rs79976124 0.879 rs12214948 chr6:66633603 G/A cg07460842 chr6:66804631 NA 0.63 6.62 0.34 1.4e-10 Type 2 diabetes; LIHC cis rs34540877 0.590 rs78187313 chr19:33141734 C/T cg22980127 chr19:33182716 NUDT19 0.89 6.22 0.32 1.43e-9 Red cell distribution width; LIHC cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg18306943 chr3:40428807 ENTPD3 -0.4 -7.21 -0.36 3.61e-12 Renal cell carcinoma; LIHC cis rs3793683 0.858 rs1571145 chr10:134583672 C/G cg27286337 chr10:134555280 INPP5A -1.01 -18.45 -0.71 3.13e-53 Migraine; LIHC cis rs6163 0.727 rs284854 chr10:104574562 T/G cg15744005 chr10:104629667 AS3MT 0.4 8.59 0.42 3.15e-16 Waist circumference;Hip circumference; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg10755058 chr3:40428713 ENTPD3 0.4 6.71 0.34 8.26e-11 Renal cell carcinoma; LIHC cis rs7647973 0.769 rs6446204 chr3:49034879 T/C cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.24 0.32 1.31e-9 Menarche (age at onset); LIHC cis rs4934494 0.634 rs12762448 chr10:91390240 A/C cg19698084 chr10:91461284 KIF20B -0.46 -6.19 -0.32 1.74e-9 Red blood cell count; LIHC trans rs7618501 0.633 rs6771546 chr3:49968572 T/C cg21659725 chr3:3221576 CRBN 0.66 10.66 0.5 4.41e-23 Intelligence (multi-trait analysis); LIHC cis rs6723226 0.572 rs176411 chr2:32643528 A/G cg02381751 chr2:32503542 YIPF4 0.53 7.87 0.39 4.72e-14 Intelligence (multi-trait analysis); LIHC trans rs7618501 1.000 rs6775384 chr3:49853073 G/A cg21582582 chr3:182698605 DCUN1D1 0.54 6.99 0.35 1.41e-11 Intelligence (multi-trait analysis); LIHC cis rs11758351 1.000 rs11754744 chr6:26202605 G/A cg16070018 chr6:26224392 HIST1H3E 0.56 6.67 0.34 1.06e-10 Gout;Renal underexcretion gout; LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg05185784 chr16:90016020 DEF8 -0.44 -5.71 -0.3 2.4e-8 Skin colour saturation; LIHC cis rs9916302 0.851 rs11870631 chr17:37645129 C/T cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs9393692 0.905 rs9366649 chr6:26329103 A/T cg13736514 chr6:26305472 NA 0.35 6.02 0.31 4.39e-9 Educational attainment; LIHC trans rs4843747 0.671 rs28451517 chr16:88109127 A/C cg09572067 chr16:29127029 RRN3P2 0.52 8.31 0.41 2.35e-15 Menopause (age at onset); LIHC cis rs8017423 0.967 rs17188605 chr14:90722579 C/T cg14092571 chr14:90743983 NA -0.38 -6.03 -0.31 4.15e-9 Mortality in heart failure; LIHC cis rs7487075 0.619 rs4768725 chr12:46848478 T/C cg23829395 chr12:46796953 NA 0.35 6.15 0.32 2.11e-9 Itch intensity from mosquito bite; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17608500 chr1:154955711 FLAD1 0.42 6.98 0.35 1.56e-11 Cognitive function; LIHC cis rs7843479 0.965 rs733543 chr8:21835465 A/G cg17168535 chr8:21777572 XPO7 0.41 6.6 0.34 1.6e-10 Mean corpuscular volume; LIHC cis rs921968 0.565 rs7599945 chr2:219641528 G/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9394841 0.536 rs6899876 chr6:41796970 A/G cg17623882 chr6:41773611 USP49 -0.42 -5.84 -0.3 1.24e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg07092213 chr7:1199455 ZFAND2A -0.45 -6.49 -0.33 3.04e-10 Longevity;Endometriosis; LIHC cis rs826838 1.000 rs826892 chr12:39100790 T/C cg13010199 chr12:38710504 ALG10B -0.39 -5.83 -0.3 1.28e-8 Heart rate; LIHC cis rs7919006 1.000 rs7919006 chr10:76808760 C/T cg01390419 chr10:76803856 DUPD1 0.49 7.33 0.37 1.68e-12 Weight; LIHC cis rs921968 0.565 rs2272189 chr2:219610322 G/A cg02985541 chr2:219472218 PLCD4 -0.36 -6.34 -0.32 7.39e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7635838 0.859 rs9826803 chr3:11461863 G/A cg00170343 chr3:11313890 ATG7 0.48 7.3 0.37 2.02e-12 HDL cholesterol; LIHC cis rs12986413 0.935 rs12980417 chr19:2184166 G/A cg09261902 chr19:2140048 AP3D1 0.4 6.72 0.34 7.53e-11 Height; LIHC cis rs10426930 0.675 rs2613772 chr19:5075787 T/C cg18473234 chr19:5097819 KDM4B -0.57 -7.33 -0.37 1.72e-12 Monocyte percentage of white cells; LIHC cis rs77106637 0.932 rs2886599 chr11:72721271 C/A cg03713592 chr11:72463424 ARAP1 0.77 6.78 0.34 5.28e-11 Type 2 diabetes; LIHC cis rs9918079 0.560 rs7685083 chr4:15610771 G/A cg21329975 chr4:15471214 CC2D2A 0.41 6.18 0.32 1.84e-9 Obesity-related traits; LIHC cis rs600806 0.778 rs2115787 chr1:110003840 T/G cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.57 -0.38 3.46e-13 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.541 rs1414347 chr6:8471831 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7078219 0.543 rs10786556 chr10:101278324 C/T cg06854084 chr10:101292507 NKX2-3 -0.35 -6.46 -0.33 3.64e-10 Dental caries; LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg20302342 chr1:156215951 PAQR6 0.32 6.2 0.32 1.65e-9 Tonsillectomy; LIHC trans rs2727020 0.688 rs2734002 chr11:49234162 A/G cg03929089 chr4:120376271 NA 0.79 13.86 0.6 5.39e-35 Coronary artery disease; LIHC cis rs240764 0.658 rs11155673 chr6:101243283 A/T cg09795085 chr6:101329169 ASCC3 -0.42 -5.84 -0.3 1.18e-8 Neuroticism; LIHC cis rs7100689 0.646 rs1047952 chr10:82126808 C/G cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09356193 chr14:105816327 PACS2 0.5 7.47 0.37 6.81e-13 Longevity; LIHC cis rs965469 0.947 rs6139087 chr20:3329062 T/C cg25506879 chr20:3388711 C20orf194 -0.57 -6.88 -0.35 2.95e-11 IFN-related cytopenia; LIHC cis rs9649213 0.593 rs34129434 chr7:97926464 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.82e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs11608355 0.705 rs4766601 chr12:109890080 C/G cg05360138 chr12:110035743 NA 0.74 8.77 0.43 8.84e-17 Neuroticism; LIHC cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.18 -0.32 1.79e-9 Aortic root size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00975115 chr16:30958403 FBXL19 -0.43 -6.19 -0.32 1.71e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1005277 0.540 rs11011351 chr10:38030525 A/G cg17830980 chr10:43048298 ZNF37B -0.42 -8.12 -0.4 8.5e-15 Extrinsic epigenetic age acceleration; LIHC cis rs2067615 0.524 rs1922433 chr12:107077172 A/G cg15890332 chr12:107067104 RFX4 0.26 6.24 0.32 1.28e-9 Heart rate; LIHC trans rs4566357 0.615 rs10184991 chr2:227916533 G/A cg16088116 chr21:44841560 SIK1 -0.42 -6.52 -0.33 2.59e-10 Coronary artery disease; LIHC cis rs10751667 0.666 rs6597967 chr11:950583 G/T cg06064525 chr11:970664 AP2A2 -0.56 -14.94 -0.63 3.43e-39 Alzheimer's disease (late onset); LIHC cis rs12477438 0.520 rs6542866 chr2:99764592 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 9.9 0.47 1.76e-20 Chronic sinus infection; LIHC cis rs904251 0.523 rs2776872 chr6:37482787 C/G cg08126542 chr6:37504118 NA -0.36 -6.2 -0.32 1.58e-9 Cognitive performance; LIHC cis rs9611565 0.500 rs10775759 chr22:42088158 T/C cg06634786 chr22:41940651 POLR3H 0.6 6.64 0.34 1.22e-10 Vitiligo; LIHC cis rs7666738 0.830 rs13121766 chr4:98935766 A/C cg05340658 chr4:99064831 C4orf37 0.7 12.96 0.57 1.54e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs637571 0.565 rs633800 chr11:65638719 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.5 -7.18 -0.36 4.39e-12 Eosinophil percentage of white cells; LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg02290350 chr8:58132656 NA 0.49 10.4 0.49 3.47e-22 Developmental language disorder (linguistic errors); LIHC cis rs7264396 0.563 rs2425114 chr20:34322346 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.47e-16 Total cholesterol levels; LIHC cis rs7116495 1.000 rs3793938 chr11:71823133 G/A cg26138937 chr11:71823887 C11orf51 0.81 7.98 0.4 2.23e-14 Severe influenza A (H1N1) infection; LIHC cis rs9911578 0.803 rs8069033 chr17:57131581 T/A cg05425664 chr17:57184151 TRIM37 0.6 8.99 0.44 1.67e-17 Intelligence (multi-trait analysis); LIHC cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg17971929 chr21:40555470 PSMG1 -0.4 -6.12 -0.31 2.5e-9 Menarche (age at onset); LIHC cis rs58688157 0.705 rs2396545 chr11:601785 T/C cg16486109 chr11:613632 IRF7 0.58 6.28 0.32 1.04e-9 Systemic lupus erythematosus; LIHC cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.53 -9.31 -0.45 1.64e-18 Bipolar disorder; LIHC cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.45 -0.59 2.13e-33 Vitiligo; LIHC cis rs7980687 0.527 rs28533432 chr12:123873242 C/T cg05973401 chr12:123451056 ABCB9 0.41 6.11 0.31 2.72e-9 Height;Educational attainment;Head circumference (infant); LIHC trans rs10411161 0.748 rs17835306 chr19:52385266 G/A cg22319618 chr22:45562946 NUP50 -0.6 -7.1 -0.36 7.48e-12 Breast cancer; LIHC trans rs800082 1.000 rs1007564 chr3:144311843 C/T cg24215973 chr2:240111563 HDAC4 -0.42 -6.1 -0.31 2.92e-9 Smoking behavior; LIHC cis rs6430585 0.793 rs11684545 chr2:136539122 G/T cg07169764 chr2:136633963 MCM6 -0.69 -9.9 -0.47 1.69e-20 Corneal structure; LIHC trans rs2270927 0.510 rs6453213 chr5:75579518 A/G cg13563193 chr19:33072644 PDCD5 1.03 10.03 0.48 6.42e-21 Mean corpuscular volume; LIHC cis rs12477438 0.684 rs6756880 chr2:99676991 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg03806693 chr22:41940476 POLR3H 1.1 13.32 0.58 6.77e-33 Vitiligo; LIHC cis rs244293 1.000 rs244299 chr17:53240266 A/C cg19360675 chr17:53046073 COX11;STXBP4 0.44 6.22 0.32 1.45e-9 Menarche (age at onset); LIHC cis rs56011263 0.687 rs73221103 chr4:706740 T/C cg14024328 chr4:719362 PCGF3 -0.47 -7.07 -0.36 8.66e-12 White blood cell count; LIHC cis rs2012796 0.661 rs59969857 chr14:81841579 A/G cg23690444 chr14:81902736 NA -0.44 -6.21 -0.32 1.53e-9 Night sleep phenotypes; LIHC cis rs57590327 0.504 rs4856348 chr3:81502923 T/G cg07356753 chr3:81810745 GBE1 0.45 6.57 0.33 1.83e-10 Extraversion; LIHC cis rs600806 0.821 rs3879451 chr1:109909269 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs9768139 0.708 rs896782 chr7:158114115 G/A cg25566285 chr7:158114605 PTPRN2 0.22 6.02 0.31 4.4e-9 Calcium levels; LIHC cis rs1046896 0.553 rs72634343 chr17:80827392 T/C cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.38 0.33 5.62e-10 Glycated hemoglobin levels; LIHC cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg11062466 chr8:58055876 NA 0.4 5.82 0.3 1.35e-8 Developmental language disorder (linguistic errors); LIHC cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg22029157 chr1:209979665 IRF6 0.5 8.18 0.4 5.68e-15 Cleft lip with or without cleft palate; LIHC cis rs4746818 1.000 rs7918066 chr10:70913116 C/T cg11621586 chr10:70884670 VPS26A 0.87 14.21 0.61 2.47e-36 Left atrial antero-posterior diameter; LIHC cis rs9543976 1.000 rs8192762 chr13:76176680 A/T cg01531495 chr13:76123901 UCHL3 0.49 5.84 0.3 1.23e-8 Diabetic retinopathy; LIHC cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.81 -0.35 4.48e-11 Gut microbiome composition (summer); LIHC cis rs11583043 0.918 rs6675403 chr1:101418569 T/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.1 0.44 7.68e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs5756813 0.715 rs5756825 chr22:38199950 T/C cg19894588 chr14:64061835 NA 0.81 14.18 0.61 3.3e-36 Optic cup area;Vertical cup-disc ratio; LIHC cis rs6942756 1.000 rs6980385 chr7:128943615 G/A cg02491457 chr7:128862824 NA -0.62 -8.87 -0.43 4.06e-17 White matter hyperintensity burden; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03698702 chr19:36236336 PSENEN;U2AF1L4 0.47 6.52 0.33 2.48e-10 Lung function (FEV1/FVC); LIHC cis rs1475911 0.671 rs12483409 chr21:43521902 G/A cg24372256 chr21:43528868 UMODL1;C21orf128 -0.36 -5.97 -0.31 5.95e-9 IgG glycosylation; LIHC cis rs2274273 0.837 rs10141483 chr14:55786871 T/C cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.37e-9 Protein biomarker; LIHC cis rs9583531 0.689 rs6492308 chr13:111377829 T/C cg15841412 chr13:111365552 ING1 0.5 6.17 0.32 1.9e-9 Coronary artery disease; LIHC cis rs6089584 0.888 rs6061966 chr20:60607936 C/G cg13770153 chr20:60521292 NA -0.34 -6.83 -0.35 3.89e-11 Body mass index; LIHC cis rs35110281 0.666 rs9977076 chr21:45085829 G/A cg21573476 chr21:45109991 RRP1B -0.59 -11.05 -0.51 1.77e-24 Mean corpuscular volume; LIHC cis rs7129220 0.588 rs61878628 chr11:10128872 T/G cg01453529 chr11:10209919 SBF2 -0.39 -6.8 -0.35 4.7e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs17685 0.671 rs60303271 chr7:75760008 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6582630 0.555 rs10880624 chr12:38526316 C/T cg13010199 chr12:38710504 ALG10B 0.44 5.96 0.31 6.15e-9 Drug-induced liver injury (flucloxacillin); LIHC trans rs13098911 0.540 rs2171531 chr3:45981171 C/T cg21656520 chr2:210867290 RPE 0.85 6.08 0.31 3.26e-9 Celiac disease; LIHC cis rs7613875 0.620 rs3774734 chr3:50108792 C/A cg21467203 chr3:49911342 NA 0.5 9.13 0.44 6.05e-18 Body mass index; LIHC cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg05535760 chr7:792225 HEATR2 -0.46 -6.34 -0.32 7.3e-10 Perceived unattractiveness to mosquitoes; LIHC cis rs7116495 0.881 rs7930142 chr11:71737016 C/T cg26138937 chr11:71823887 C11orf51 -0.81 -8.04 -0.4 1.43e-14 Severe influenza A (H1N1) infection; LIHC cis rs651907 0.557 rs36002990 chr3:101437862 G/A cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.74 -0.3 2.04e-8 Colorectal cancer; LIHC cis rs7091957 1.000 rs7091957 chr10:134439478 C/T cg27286337 chr10:134555280 INPP5A 0.59 9.76 0.47 5.12e-20 Gait speed in old age; LIHC cis rs9888615 0.646 rs11157934 chr14:53365816 A/G cg00686598 chr14:53173677 PSMC6 -0.47 -6.36 -0.33 6.33e-10 Systolic blood pressure; LIHC cis rs67478160 0.619 rs11160759 chr14:104231542 C/T cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.6 -0.38 2.91e-13 Schizophrenia; LIHC cis rs208515 0.556 rs1872309 chr6:66660432 A/C cg07460842 chr6:66804631 NA 0.75 8.4 0.41 1.19e-15 Exhaled nitric oxide levels; LIHC cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg10802521 chr3:52805072 NEK4 -0.43 -6.86 -0.35 3.27e-11 Bipolar disorder; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.62 0.38 2.44e-13 Prudent dietary pattern; LIHC cis rs7647973 0.626 rs4855846 chr3:49683526 G/A cg03060546 chr3:49711283 APEH 0.61 7.03 0.36 1.09e-11 Menarche (age at onset); LIHC cis rs7917772 0.582 rs6584512 chr10:104329685 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.17e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9457247 1.000 rs376551 chr6:167384923 G/A cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs2797160 1.000 rs2747720 chr6:126009458 A/G cg05901451 chr6:126070800 HEY2 0.45 7.44 0.37 8.16e-13 Endometrial cancer; LIHC cis rs6963495 0.674 rs75880756 chr7:105163821 G/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs62103177 0.810 rs62103197 chr18:77632923 G/A cg05926928 chr17:57297772 GDPD1 1.14 11.67 0.53 1e-26 Opioid sensitivity; LIHC cis rs1707322 1.000 rs785470 chr1:46519622 C/A cg06784218 chr1:46089804 CCDC17 -0.36 -6.5 -0.33 2.8e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.681 rs12048866 chr1:46117492 T/G cg03146154 chr1:46216737 IPP 0.57 9.74 0.47 5.94e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg11645453 chr3:52864694 ITIH4 -0.22 -6.16 -0.32 1.99e-9 Bipolar disorder; LIHC cis rs12477438 0.539 rs62156558 chr2:99553104 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -12.36 -0.56 2.79e-29 Chronic sinus infection; LIHC cis rs72634258 0.945 rs34157438 chr1:8023586 C/T cg00042356 chr1:8021962 PARK7 0.9 9.08 0.44 8.51e-18 Inflammatory bowel disease; LIHC cis rs765787 0.530 rs1631533 chr15:45518628 C/T cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.74 -0.3 2.1e-8 Uric acid levels; LIHC cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.83 -0.39 6.02e-14 Type 2 diabetes; LIHC cis rs769267 0.930 rs6511038 chr19:19607564 A/C cg03709012 chr19:19516395 GATAD2A 1.01 18.36 0.7 6.84e-53 Tonsillectomy; LIHC cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg13047869 chr3:10149882 C3orf24 0.49 6.39 0.33 5.37e-10 Alzheimer's disease; LIHC cis rs72627123 0.867 rs77321049 chr14:74455219 G/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.46 0.42 8.11e-16 Morning vs. evening chronotype; LIHC cis rs7651039 1.000 rs7651039 chr3:15648004 C/T cg16303742 chr3:15540471 COLQ -0.52 -9.03 -0.44 1.32e-17 Coronary heart disease; LIHC cis rs1577917 0.682 rs6935918 chr6:86283575 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.27 0.32 1.07e-9 Response to antipsychotic treatment; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg05484376 chr2:27715224 FNDC4 0.36 6.16 0.32 2.07e-9 Total body bone mineral density; LIHC cis rs4650994 0.593 rs7552110 chr1:178542154 A/T cg05350800 chr1:178550844 NA -0.35 -7.64 -0.38 2.26e-13 HDL cholesterol levels;HDL cholesterol; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03627896 chr16:30934334 NCRNA00095 0.47 6.72 0.34 7.49e-11 Cognitive function; LIHC cis rs3812831 0.695 rs7995986 chr13:114938802 A/G cg08824895 chr13:115047677 UPF3A 0.49 7.11 0.36 7.01e-12 Schizophrenia; LIHC cis rs600806 0.888 rs12046539 chr1:109875415 C/T cg16275483 chr1:110013120 SYPL2 -0.49 -6.11 -0.31 2.76e-9 Intelligence (multi-trait analysis); LIHC cis rs151997 0.671 rs152926 chr5:50201787 G/A cg06027927 chr5:50259733 NA -0.45 -6.64 -0.34 1.25e-10 Callous-unemotional behaviour; LIHC trans rs11039798 1.000 rs7125559 chr11:48984207 C/G cg15704280 chr7:45808275 SEPT13 0.62 6.4 0.33 5.11e-10 Axial length; LIHC cis rs807029 0.533 rs2295716 chr10:102744214 T/C cg27255678 chr10:102756921 LZTS2 0.52 7.31 0.37 1.85e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2637266 0.935 rs2583054 chr10:78401442 A/G cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs4713118 0.869 rs6930992 chr6:27712120 A/C cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs4237845 0.742 rs3751330 chr12:58290226 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.44 6.15 0.32 2.13e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg09455208 chr3:40491958 NA 0.4 8.09 0.4 1.05e-14 Renal cell carcinoma; LIHC cis rs1348850 0.914 rs2060929 chr2:178280031 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.86 13.56 0.59 8.18e-34 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs734999 0.505 rs10910108 chr1:2539532 A/G cg18854424 chr1:2615690 NA 0.33 7.38 0.37 1.19e-12 Ulcerative colitis; LIHC cis rs1577917 1.000 rs12663690 chr6:86640162 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.43 7.06 0.36 9.37e-12 Response to antipsychotic treatment; LIHC cis rs4727027 0.901 rs6944781 chr7:148829566 A/G cg23583168 chr7:148888333 NA -0.73 -10.26 -0.49 1.02e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg08888203 chr3:10149979 C3orf24 0.55 6.36 0.33 6.56e-10 Alzheimer's disease; LIHC cis rs6840360 0.615 rs1561916 chr4:152479234 C/T cg22705602 chr4:152727874 NA -0.33 -6.35 -0.32 6.71e-10 Intelligence (multi-trait analysis); LIHC trans rs2832191 0.655 rs2247110 chr21:30323888 G/A cg14791747 chr16:20752902 THUMPD1 0.48 6.61 0.34 1.44e-10 Dental caries; LIHC cis rs2380220 0.574 rs9374322 chr6:95998994 G/A cg15832292 chr6:96025679 MANEA 0.59 7.82 0.39 6.63e-14 Behavioural disinhibition (generation interaction); LIHC cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg12903224 chr12:29470962 FAR2 -0.4 -6.39 -0.33 5.49e-10 QT interval; LIHC trans rs7246657 0.891 rs7257495 chr19:37823876 C/G cg10208301 chr11:6592745 DNHD1 0.47 6.68 0.34 9.96e-11 Coronary artery calcification; LIHC cis rs2243480 0.901 rs778693 chr7:65872345 T/G cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs17539620 0.624 rs62432746 chr6:154838986 A/G cg17771515 chr6:154831774 CNKSR3 0.58 6.14 0.32 2.25e-9 Lipoprotein (a) levels; LIHC cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 9.92 0.47 1.54e-20 Platelet count; LIHC cis rs7208859 0.623 rs11656844 chr17:29060597 G/T cg14067834 chr17:29058358 SUZ12P 0.68 6.79 0.34 5.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9818758 0.607 rs9850917 chr3:49286983 A/G cg06212747 chr3:49208901 KLHDC8B -0.65 -5.77 -0.3 1.75e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs17401966 0.838 rs6541089 chr1:10402785 A/G cg19773385 chr1:10388646 KIF1B -0.4 -6.97 -0.35 1.67e-11 Hepatocellular carcinoma; LIHC cis rs12893668 0.703 rs55751606 chr14:104028806 G/A cg24130564 chr14:104152367 KLC1 -0.56 -9.2 -0.45 3.52e-18 Reticulocyte count; LIHC cis rs265548 0.608 rs36690 chr19:17910483 C/T cg16024904 chr19:17905718 B3GNT3 0.42 6.05 0.31 3.79e-9 Tumor biomarkers; LIHC cis rs9790314 1.000 rs336585 chr3:161081670 A/G cg04691961 chr3:161091175 C3orf57 -0.45 -7.08 -0.36 8.04e-12 Morning vs. evening chronotype; LIHC cis rs644799 0.710 rs523153 chr11:95570961 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 12.09 0.55 2.84e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs688020 1.000 rs673500 chr7:4229445 C/G cg24441899 chr7:4244372 SDK1 -0.29 -6.07 -0.31 3.44e-9 Liver fibrosis in pediatric non-alcoholic fatty acid liver disease; LIHC trans rs11098499 0.866 rs12374352 chr4:120281977 C/T cg25214090 chr10:38739885 LOC399744 0.48 7.67 0.38 1.8e-13 Corneal astigmatism; LIHC trans rs208520 1.000 rs208523 chr6:66954195 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.69 -0.34 9.29e-11 Exhaled nitric oxide output; LIHC cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Bipolar disorder; LIHC cis rs7249142 0.549 rs62135499 chr19:19294237 T/C cg24446071 chr19:19281270 LOC729991-MEF2B;MEF2B -0.35 -5.72 -0.3 2.32e-8 IgG glycosylation; LIHC cis rs332507 0.830 rs12631364 chr3:124405042 A/T cg05980111 chr3:124395277 KALRN 0.45 6.91 0.35 2.34e-11 Plateletcrit; LIHC cis rs9457247 0.765 rs10455982 chr6:167448728 C/T cg23791538 chr6:167370224 RNASET2 -0.53 -8.04 -0.4 1.46e-14 Crohn's disease; LIHC cis rs703842 1.000 rs11172335 chr12:58175201 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.27 0.61 1.46e-36 Multiple sclerosis; LIHC cis rs6061231 1.000 rs13043313 chr20:60958269 A/G cg03945807 chr20:60948434 NA 0.39 6.49 0.33 3.07e-10 Colorectal cancer; LIHC cis rs7044106 0.762 rs4837790 chr9:123446325 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.94 0.51 4.32e-24 Hip circumference adjusted for BMI; LIHC cis rs4253772 0.638 rs6007845 chr22:46718417 A/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.72 -6.15 -0.32 2.14e-9 LDL cholesterol;Cholesterol, total; LIHC cis rs6912958 0.559 rs1201409 chr6:88055264 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.2 0.36 3.76e-12 Monocyte percentage of white cells; LIHC trans rs7193541 0.684 rs9931225 chr16:74699293 T/C cg23598604 chr1:99732472 LPPR4 -0.3 -6.06 -0.31 3.5e-9 Multiple myeloma; LIHC cis rs9402673 0.558 rs9688342 chr6:135323026 A/T cg24558204 chr6:135376177 HBS1L 0.39 6.5 0.33 2.9e-10 Reticulocyte count;High light scatter reticulocyte count; LIHC cis rs798554 0.836 rs798500 chr7:2790685 C/T cg19346786 chr7:2764209 NA 0.48 7.31 0.37 1.94e-12 Height; LIHC trans rs75804782 0.690 rs56198112 chr2:239348887 A/G cg01134436 chr17:81009848 B3GNTL1 0.8 6.95 0.35 1.89e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs2645694 0.626 rs2645705 chr4:77830434 G/A cg03477792 chr4:77819574 ANKRD56 0.55 7.29 0.37 2.14e-12 Emphysema distribution in smoking; LIHC cis rs950169 0.922 rs67804993 chr15:85104030 T/G cg12863693 chr15:85201151 NMB 0.43 6.13 0.31 2.36e-9 Schizophrenia; LIHC cis rs9303401 0.614 rs62084387 chr17:57148027 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.01 0.58 1.08e-31 Cognitive test performance; LIHC cis rs11690935 0.632 rs34531723 chr2:172564094 A/C cg13550731 chr2:172543902 DYNC1I2 0.63 11.79 0.54 3.78e-27 Schizophrenia; LIHC cis rs2297440 0.506 rs2236504 chr20:62224762 C/T cg09650180 chr20:62225654 GMEB2 -0.39 -6.01 -0.31 4.72e-9 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg06238570 chr21:40685208 BRWD1 -0.47 -7.45 -0.37 7.78e-13 Cognitive function; LIHC cis rs6783573 0.510 rs11718490 chr3:46628763 C/T cg21489266 chr3:46619131 LRRC2;TDGF1 -0.43 -6.1 -0.31 2.86e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs950169 0.840 rs72748702 chr15:84915246 A/G cg17507749 chr15:85114479 UBE2QP1 0.74 8.9 0.43 3.43e-17 Schizophrenia; LIHC cis rs9814567 1.000 rs13081177 chr3:134289860 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.86 0.3 1.08e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9322817 0.691 rs4299867 chr6:105325383 G/C cg02098413 chr6:105308735 HACE1 0.41 7.7 0.38 1.49e-13 Thyroid stimulating hormone; LIHC cis rs4819052 0.808 rs2838825 chr21:46655651 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.49 6.76 0.34 5.9e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4969178 0.560 rs4969182 chr17:76393030 T/C cg02836325 chr17:76403955 PGS1 0.33 6.55 0.33 2.09e-10 HDL cholesterol levels; LIHC cis rs400736 0.729 rs9434949 chr1:8006083 C/G cg25007680 chr1:8021821 PARK7 -0.48 -7.57 -0.38 3.44e-13 Response to antidepressants and depression; LIHC cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg04944784 chr2:26401820 FAM59B 0.71 9.07 0.44 9.7e-18 Gut microbiome composition (summer); LIHC cis rs916888 0.773 rs199445 chr17:44817408 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.72 6.92 0.35 2.18e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7267979 0.808 rs84816 chr20:25459919 G/A cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.8 0.35 4.69e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs6089584 0.627 rs13045575 chr20:60565596 G/A cg06108461 chr20:60628389 TAF4 -0.54 -7.4 -0.37 1.07e-12 Body mass index; LIHC cis rs763121 0.853 rs138702 chr22:39132601 A/T cg06544989 chr22:39130855 UNC84B -0.35 -5.72 -0.3 2.36e-8 Menopause (age at onset); LIHC cis rs2073300 0.609 rs6137948 chr20:23416845 G/A cg16736954 chr20:23401023 NAPB 0.71 8.21 0.41 4.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs12477438 0.501 rs12613624 chr2:99732741 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.59 -10.81 -0.5 1.22e-23 Chronic sinus infection; LIHC cis rs1355223 0.583 rs2915177 chr11:34880266 A/G cg24088639 chr11:34937564 PDHX;APIP -0.38 -6.0 -0.31 5.09e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs1853665 0.580 rs4242283 chr6:150273406 C/G cg16301758 chr6:150275521 NA 0.4 6.15 0.32 2.18e-9 Radiation response; LIHC cis rs2280018 0.963 rs12928424 chr16:15150773 C/G cg07549590 chr16:15018862 NA -0.34 -6.43 -0.33 4.25e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs7618501 0.933 rs6809431 chr3:49804119 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.81 15.13 0.63 6.04e-40 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs3806843 1.000 rs10477033 chr5:140169603 G/C cg26395211 chr5:140044315 WDR55 -0.41 -6.09 -0.31 3.04e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs35110281 0.633 rs4819289 chr21:45120237 A/G cg04455712 chr21:45112962 RRP1B 0.46 8.23 0.41 3.92e-15 Mean corpuscular volume; LIHC cis rs2439831 1.000 rs689596 chr15:43761717 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.46 0.59 1.91e-33 Lung cancer in ever smokers; LIHC cis rs644799 0.965 rs502521 chr11:95533557 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 10.02 0.48 6.82e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs8114671 0.836 rs1885114 chr20:33577361 A/G cg07148914 chr20:33460835 GGT7 -0.57 -8.68 -0.43 1.6e-16 Height; LIHC cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg11644478 chr21:40555479 PSMG1 0.8 9.86 0.47 2.41e-20 Cognitive function; LIHC cis rs2380220 0.606 rs9488080 chr6:96006973 A/G cg15832292 chr6:96025679 MANEA 0.62 8.39 0.41 1.28e-15 Behavioural disinhibition (generation interaction); LIHC cis rs919433 0.926 rs787996 chr2:198216805 A/G cg10820045 chr2:198174542 NA 0.53 8.7 0.43 1.44e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs228769 0.543 rs170634 chr17:42175821 C/A cg19774624 chr17:42201019 HDAC5 0.51 6.24 0.32 1.3e-9 Bone mineral density (hip);Bone mineral density (spine); LIHC cis rs9534288 0.830 rs7987953 chr13:46634395 C/T cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC trans rs7726839 0.561 rs6555357 chr5:560923 A/G cg25482853 chr8:67687455 SGK3 0.62 6.77 0.34 5.53e-11 Obesity-related traits; LIHC cis rs2976388 0.609 rs2717602 chr8:143805683 G/A cg06565975 chr8:143823917 SLURP1 0.33 6.14 0.32 2.24e-9 Urinary tract infection frequency; LIHC cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg12463550 chr7:65579703 CRCP -0.67 -6.86 -0.35 3.29e-11 Diabetic kidney disease; LIHC cis rs4629710 0.592 rs67399092 chr6:131582936 G/A cg12606694 chr6:131520996 AKAP7 0.66 7.4 0.37 1.08e-12 Multiple myeloma (IgH translocation); LIHC cis rs10106298 0.846 rs1550005 chr8:103681662 C/G cg10187029 chr8:103597600 NA 0.46 6.17 0.32 1.9e-9 Schizophrenia; LIHC cis rs10876993 1.000 rs10876993 chr12:58062667 C/T cg18357645 chr12:58087776 OS9 0.52 8.56 0.42 3.83e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs35110281 0.681 rs162343 chr21:44957072 A/G cg04455712 chr21:45112962 RRP1B 0.44 7.22 0.36 3.4e-12 Mean corpuscular volume; LIHC cis rs13064411 0.627 rs28710051 chr3:113143531 G/A cg18753928 chr3:113234510 CCDC52 -0.42 -5.74 -0.3 2.05e-8 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs1577917 0.682 rs6909767 chr6:86228109 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.02 0.44 1.37e-17 Response to antipsychotic treatment; LIHC cis rs8103278 0.740 rs72626215 chr19:46294136 G/A cg14061069 chr19:46274453 DMPK -0.47 -6.76 -0.34 6.08e-11 Coronary artery disease; LIHC cis rs1552244 0.882 rs7633769 chr3:10020622 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.69 -11.01 -0.51 2.51e-24 Alzheimer's disease; LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg16358155 chr3:195490169 MUC4 0.45 6.84 0.35 3.76e-11 Lung disease severity in cystic fibrosis; LIHC cis rs4919087 0.962 rs3814164 chr10:98982749 G/A cg25902810 chr10:99078978 FRAT1 0.64 9.41 0.45 7.22e-19 Monocyte count; LIHC cis rs1707322 0.717 rs2275086 chr1:46085879 C/G cg24296786 chr1:45957014 TESK2 0.42 5.99 0.31 5.41e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6750047 0.625 rs336036 chr2:38261143 C/T cg07380506 chr2:38303506 CYP1B1 -0.55 -6.93 -0.35 2.09e-11 Cutaneous malignant melanoma;Melanoma; LIHC cis rs2070488 0.965 rs2154778 chr3:38553639 C/T cg24069376 chr3:38537580 EXOG -0.39 -7.04 -0.36 1.09e-11 Electrocardiographic conduction measures; LIHC cis rs6424115 0.965 rs2502986 chr1:24135292 G/T cg10978503 chr1:24200527 CNR2 0.37 8.83 0.43 5.34e-17 Immature fraction of reticulocytes; LIHC cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg06453172 chr10:134556979 INPP5A -0.61 -8.46 -0.42 8.09e-16 Migraine; LIHC cis rs968567 0.817 rs61896141 chr11:61556039 A/C cg06781209 chr11:61594997 FADS2 -0.69 -6.44 -0.33 4.1e-10 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs12594515 0.935 rs8042519 chr15:45996341 G/C cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs2075371 1.000 rs2598297 chr7:133993001 T/G cg11752832 chr7:134001865 SLC35B4 0.52 7.63 0.38 2.33e-13 Mean platelet volume; LIHC cis rs8016982 0.698 rs8011097 chr14:81702736 T/C cg01989461 chr14:81687754 GTF2A1 0.64 12.8 0.57 6.22e-31 Schizophrenia; LIHC cis rs2380220 1.000 rs9400318 chr6:95972381 T/A cg15832292 chr6:96025679 MANEA 0.63 6.98 0.35 1.58e-11 Behavioural disinhibition (generation interaction); LIHC cis rs7258015 0.865 rs7250656 chr19:10448566 A/G cg13981319 chr19:10446556 ICAM3 0.46 7.21 0.36 3.68e-12 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs2421770 0.530 rs4756218 chr11:35370113 G/A cg13971030 chr11:35366721 SLC1A2 -0.45 -7.59 -0.38 3.02e-13 Staphylococcus aureus nasal carriage (persistent); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg18266620 chr1:110882148 RBM15 -0.39 -6.03 -0.31 4.18e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs4803468 1.000 rs2231940 chr19:41944237 T/C cg09537434 chr19:41945824 ATP5SL 1.02 21.29 0.75 1.19e-64 Height; LIHC cis rs782590 0.967 rs1084522 chr2:55843294 A/G cg18811423 chr2:55921094 PNPT1 0.99 16.06 0.66 1.2e-43 Metabolic syndrome; LIHC cis rs6442522 0.526 rs909354 chr3:15520244 C/T cg16303742 chr3:15540471 COLQ 0.36 5.88 0.3 9.93e-9 Uric acid levels; LIHC cis rs7927771 0.864 rs7937331 chr11:47430458 T/C cg20307385 chr11:47447363 PSMC3 0.51 6.77 0.34 5.75e-11 Subjective well-being; LIHC cis rs6570726 0.791 rs6900040 chr6:145893134 C/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.5 -0.33 2.91e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10744422 1.000 rs2292135 chr12:123334075 G/A cg22842854 chr12:123319900 HIP1R -0.74 -9.7 -0.46 8.23e-20 Schizophrenia; LIHC cis rs9486715 0.867 rs9373833 chr6:96904998 A/G cg06623918 chr6:96969491 KIAA0776 -0.86 -15.13 -0.63 6.18e-40 Headache; LIHC cis rs7592578 0.508 rs62180987 chr2:191267173 A/G cg27211696 chr2:191398769 TMEM194B -0.44 -5.83 -0.3 1.3e-8 Diastolic blood pressure; LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg04234412 chr22:24373322 LOC391322 0.65 9.23 0.45 2.89e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7572733 0.555 rs1435569 chr2:198718667 G/C cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC trans rs4332037 0.826 rs4721188 chr7:1953615 G/A cg11693508 chr17:37793320 STARD3 -0.68 -7.39 -0.37 1.12e-12 Bipolar disorder; LIHC trans rs35110281 0.837 rs2838343 chr21:45078035 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.45 0.33 3.82e-10 Mean corpuscular volume; LIHC trans rs7726839 0.540 rs3749615 chr5:601485 C/T cg25482853 chr8:67687455 SGK3 0.6 6.13 0.31 2.43e-9 Obesity-related traits; LIHC cis rs4555082 0.834 rs1473672 chr14:105721981 G/T cg06808227 chr14:105710500 BRF1 -0.55 -7.21 -0.36 3.58e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs921968 0.608 rs678814 chr2:219359287 T/C cg18887096 chr2:219472410 PLCD4 0.36 6.39 0.33 5.46e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7619427 1.000 rs7610078 chr3:44074018 C/T cg24966902 chr3:44043705 NA 0.52 7.61 0.38 2.63e-13 Schizophrenia; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14531310 chr9:34401237 C9orf25 0.38 6.11 0.31 2.79e-9 Bilirubin levels; LIHC cis rs8044995 0.563 rs61746794 chr16:68387457 C/T cg05110241 chr16:68378359 PRMT7 -0.87 -9.82 -0.47 3.27e-20 Schizophrenia; LIHC cis rs986417 0.748 rs1956552 chr14:60942685 A/G cg27398547 chr14:60952738 C14orf39 0.72 7.97 0.4 2.39e-14 Gut microbiota (bacterial taxa); LIHC cis rs74181299 0.570 rs10197530 chr2:65355604 T/A cg05010058 chr2:65284262 CEP68 -0.41 -6.74 -0.34 6.94e-11 Pulse pressure; LIHC cis rs11098499 1.000 rs10029750 chr4:120172543 A/G cg09307838 chr4:120376055 NA 0.74 10.99 0.51 2.94e-24 Corneal astigmatism; LIHC cis rs240764 0.817 rs239226 chr6:101107969 G/C cg09795085 chr6:101329169 ASCC3 0.53 7.46 0.37 7.07e-13 Neuroticism; LIHC cis rs910316 0.967 rs119076 chr14:75572419 G/T cg08847533 chr14:75593920 NEK9 -0.88 -19.19 -0.72 3.14e-56 Height; LIHC cis rs7647973 0.667 rs9869256 chr3:49624095 T/G cg03060546 chr3:49711283 APEH 0.56 5.95 0.31 6.77e-9 Menarche (age at onset); LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg24209194 chr3:40518798 ZNF619 0.63 9.62 0.46 1.51e-19 Renal cell carcinoma; LIHC cis rs1570884 0.516 rs9526580 chr13:50164023 C/G cg08779649 chr13:50194554 NA -0.31 -5.73 -0.3 2.18e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs754466 0.651 rs55738779 chr10:79652395 C/T cg17075019 chr10:79541650 NA -0.74 -10.79 -0.5 1.52e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10540 1.000 rs35898083 chr11:484469 C/T cg03576123 chr11:487126 PTDSS2 -1.0 -7.64 -0.38 2.18e-13 Body mass index; LIHC cis rs7613875 0.620 rs11721204 chr3:49982765 C/T cg21467203 chr3:49911342 NA -0.51 -9.37 -0.45 1.02e-18 Body mass index; LIHC cis rs6963495 0.818 rs73192125 chr7:105175068 A/C cg19920283 chr7:105172520 RINT1 0.66 6.35 0.32 6.89e-10 Bipolar disorder (body mass index interaction); LIHC cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg02290350 chr8:58132656 NA 0.5 8.99 0.44 1.74e-17 Developmental language disorder (linguistic errors); LIHC cis rs12142240 0.698 rs45517837 chr1:46859225 A/G cg14993813 chr1:46806288 NSUN4 -0.66 -5.97 -0.31 5.89e-9 Menopause (age at onset); LIHC cis rs2066819 1.000 rs75598973 chr12:56746558 C/T cg26714650 chr12:56694279 CS -1.35 -12.74 -0.57 1.09e-30 Psoriasis vulgaris; LIHC cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 12.11 0.55 2.49e-28 Platelet count; LIHC trans rs11098499 1.000 rs6849889 chr4:120186348 A/C cg25214090 chr10:38739885 LOC399744 0.5 7.6 0.38 2.92e-13 Corneal astigmatism; LIHC cis rs9914988 0.943 rs7217547 chr17:27106872 C/G cg20469991 chr17:27169893 C17orf63 -0.54 -6.42 -0.33 4.61e-10 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6598955 0.670 rs10794525 chr1:26537193 C/A cg00852783 chr1:26633632 UBXN11 0.47 7.97 0.4 2.37e-14 Obesity-related traits; LIHC cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.51 5.8 0.3 1.51e-8 Cerebrospinal P-tau181p levels; LIHC cis rs2274273 0.837 rs6573017 chr14:55802243 G/A cg04306507 chr14:55594613 LGALS3 0.32 5.96 0.31 6.19e-9 Protein biomarker; LIHC cis rs7312933 0.618 rs7315968 chr12:42637086 G/A cg17420585 chr12:42539391 GXYLT1 -0.35 -5.74 -0.3 2.12e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11673344 0.765 rs826296 chr19:37438286 A/G cg27390819 chr19:37464633 NA -0.52 -6.22 -0.32 1.42e-9 Obesity-related traits; LIHC cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg03264133 chr6:25882463 NA -0.63 -8.98 -0.44 1.91e-17 Blood metabolite levels; LIHC cis rs1707322 0.963 rs4553121 chr1:46375253 G/A cg03146154 chr1:46216737 IPP 0.47 7.66 0.38 1.88e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11603020 0.950 rs11229066 chr11:57374871 C/G cg19752551 chr11:57585705 CTNND1 -0.46 -5.9 -0.3 8.98e-9 Blood protein levels; LIHC cis rs35110281 0.667 rs2155722 chr21:45096206 A/G cg04455712 chr21:45112962 RRP1B -0.54 -9.67 -0.46 1.07e-19 Mean corpuscular volume; LIHC cis rs2718798 1 rs2718798 chr3:133492088 A/C cg12373951 chr3:133503437 NA 0.53 8.8 0.43 6.65e-17 Ankle injury; LIHC cis rs7937890 1.000 rs6486190 chr11:14401216 A/C cg19336497 chr11:14380999 RRAS2 -0.36 -6.12 -0.31 2.54e-9 Mitochondrial DNA levels; LIHC cis rs2637266 0.597 rs2583065 chr10:78555915 A/G cg18941641 chr10:78392320 NA 0.3 6.46 0.33 3.58e-10 Pulmonary function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11212172 chr10:53459438 PRKG1;CSTF2T 0.45 7.13 0.36 6.17e-12 Cognitive function; LIHC cis rs1865721 0.682 rs35282535 chr18:73141206 G/A cg26385618 chr18:73139727 C18orf62 -0.29 -8.22 -0.41 4.24e-15 Intelligence; LIHC cis rs754466 0.606 rs11002310 chr10:79596030 A/C cg17075019 chr10:79541650 NA -0.75 -11.65 -0.53 1.23e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs11098499 1.000 rs12506395 chr4:120185094 C/T cg25214090 chr10:38739885 LOC399744 0.53 7.98 0.4 2.24e-14 Corneal astigmatism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02804564 chr10:112679224 NCRNA00081;SHOC2 0.44 7.15 0.36 5.44e-12 Cognitive function; LIHC cis rs2334880 0.678 rs12918320 chr16:71463602 A/G cg06353428 chr16:71660113 MARVELD3 -0.97 -9.46 -0.46 5.06e-19 Malaria; LIHC cis rs611744 0.967 rs688746 chr8:109225725 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs76419734 0.510 rs2544417 chr4:106745405 A/G cg24545054 chr4:106630052 GSTCD;INTS12 -0.71 -7.24 -0.36 3.03e-12 Post bronchodilator FEV1; LIHC cis rs2191566 0.821 rs62119173 chr19:44518073 G/A cg18700516 chr19:44507157 ZNF230 -0.35 -5.86 -0.3 1.11e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs9467773 1.000 rs9295695 chr6:26528250 C/T cg09904177 chr6:26538194 HMGN4 -0.66 -13.7 -0.6 2.43e-34 Intelligence (multi-trait analysis); LIHC cis rs3820500 1.000 rs3820500 chr1:118013322 A/G cg20383390 chr1:117909022 MAN1A2 -0.44 -5.87 -0.3 1.01e-8 Pneumonia; LIHC cis rs963731 0.649 rs297140 chr2:39319121 A/G cg04010122 chr2:39346883 SOS1 -0.68 -5.95 -0.31 6.6e-9 Corticobasal degeneration; LIHC cis rs2153535 0.580 rs2152348 chr6:8474301 C/A cg21535247 chr6:8435926 SLC35B3 0.61 8.06 0.4 1.29e-14 Motion sickness; LIHC cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg11062466 chr8:58055876 NA 0.51 6.88 0.35 2.79e-11 Developmental language disorder (linguistic errors); LIHC cis rs11955398 0.529 rs62373032 chr5:59956159 G/C cg02684056 chr5:59996105 DEPDC1B 0.39 5.81 0.3 1.44e-8 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg09417038 chr21:47716443 C21orf57 0.52 7.94 0.39 2.93e-14 Testicular germ cell tumor; LIHC cis rs4919694 1.000 rs11191525 chr10:104793435 G/C cg04362960 chr10:104952993 NT5C2 1.15 9.07 0.44 9.6e-18 Arsenic metabolism; LIHC cis rs3764563 0.877 rs4646526 chr19:15729773 A/G cg20725493 chr19:15740067 CYP4F8 -0.66 -5.72 -0.3 2.34e-8 Inflammatory biomarkers; LIHC trans rs7615952 0.558 rs7641353 chr3:125339879 T/C cg07211511 chr3:129823064 LOC729375 -0.46 -6.29 -0.32 9.58e-10 Blood pressure (smoking interaction); LIHC cis rs6570726 0.791 rs9373464 chr6:145907167 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.0 0.51 2.64e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs597539 0.617 rs686348 chr11:68636996 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.08e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs68170813 0.559 rs78610616 chr7:106951369 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.88 -0.3 9.71e-9 Coronary artery disease; LIHC cis rs7523273 0.526 rs1204706 chr1:208021060 G/T cg22525895 chr1:207977042 MIR29B2 -0.59 -9.1 -0.44 7.76e-18 Schizophrenia; LIHC cis rs7592578 0.882 rs58568707 chr2:191468987 G/A cg10560079 chr2:191398806 TMEM194B -0.87 -12.24 -0.55 8.17e-29 Diastolic blood pressure; LIHC trans rs1814175 0.817 rs10769618 chr11:49822336 A/G cg03929089 chr4:120376271 NA -0.9 -18.33 -0.7 9.41e-53 Height; LIHC cis rs9517320 0.534 rs3858778 chr13:99172249 A/C cg20487152 chr13:99095054 FARP1 0.38 6.23 0.32 1.37e-9 Longevity; LIHC cis rs7607369 0.714 rs55900247 chr2:219618708 T/C cg02985541 chr2:219472218 PLCD4 -0.38 -5.91 -0.3 8.4e-9 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs2645694 0.626 rs2703115 chr4:77824442 C/T cg06046430 chr4:77819534 ANKRD56 0.51 6.89 0.35 2.68e-11 Emphysema distribution in smoking; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27576415 chr15:41709087 RTF1 0.41 6.42 0.33 4.59e-10 Cognitive function; LIHC cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs262150 0.579 rs4909110 chr7:158787332 C/T cg13444538 chr7:158905317 VIPR2 -0.32 -5.95 -0.31 6.65e-9 Facial morphology (factor 20); LIHC cis rs244293 1.000 rs244292 chr17:53230734 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.33 -0.37 1.65e-12 Menarche (age at onset); LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg06873352 chr17:61820015 STRADA 0.61 9.45 0.46 5.37e-19 Height; LIHC trans rs11985561 1.000 rs11985561 chr8:3452262 A/C cg21587066 chr13:37004940 CCNA1 0.5 6.55 0.33 2.14e-10 Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid); LIHC cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg24531977 chr5:56204891 C5orf35 -0.67 -9.66 -0.46 1.11e-19 Initial pursuit acceleration; LIHC cis rs2282802 0.685 rs6893253 chr5:139661279 T/C cg26211634 chr5:139558579 C5orf32 0.38 5.85 0.3 1.17e-8 Intelligence (multi-trait analysis); LIHC cis rs6500602 1.000 rs7204827 chr16:4467533 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 5.88 0.3 9.78e-9 Schizophrenia; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg07772128 chr15:75095447 CSK -0.48 -6.43 -0.33 4.26e-10 Glycated hemoglobin levels; LIHC cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 11.46 0.53 5.76e-26 Platelet count; LIHC cis rs10242455 0.571 rs11972210 chr7:99206943 A/C cg18809830 chr7:99032528 PTCD1 -0.78 -6.21 -0.32 1.53e-9 Blood metabolite levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07729303 chr15:22940817 CYFIP1 0.42 6.98 0.35 1.58e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs208520 0.674 rs207103 chr6:66795568 G/T cg07460842 chr6:66804631 NA -0.85 -9.19 -0.45 3.91e-18 Exhaled nitric oxide output; LIHC cis rs7772486 0.875 rs9376975 chr6:146355581 T/G cg23711669 chr6:146136114 FBXO30 0.66 11.76 0.54 4.95e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.644 rs719230 chr21:40676307 C/T cg06238570 chr21:40685208 BRWD1 -0.55 -9.01 -0.44 1.53e-17 Cognitive function; LIHC cis rs690037 0.551 rs690522 chr3:16377067 C/T cg23474789 chr3:16306055 DPH3;OXNAD1 -0.61 -9.07 -0.44 9.29e-18 Optic nerve measurement (cup-to-disc ratio);Optic nerve measurement (cup area); LIHC trans rs2727020 0.675 rs7929401 chr11:49350832 C/A cg18944383 chr4:111397179 ENPEP 0.32 7.21 0.36 3.69e-12 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18502334 chr7:4681577 NA 0.51 6.65 0.34 1.16e-10 Lung function (FEV1/FVC); LIHC cis rs7301016 0.846 rs11174575 chr12:63026392 G/A cg11441379 chr12:63026424 NA 0.61 6.22 0.32 1.45e-9 IgG glycosylation; LIHC cis rs2072499 0.966 rs1137703 chr1:156184458 T/C cg25208724 chr1:156163844 SLC25A44 0.92 15.83 0.65 9.93e-43 Testicular germ cell tumor; LIHC cis rs28374715 0.681 rs7163989 chr15:41614621 A/G cg18705301 chr15:41695430 NDUFAF1 -0.97 -13.28 -0.58 1e-32 Ulcerative colitis; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg01399255 chr7:100271274 GNB2 -0.45 -6.62 -0.34 1.36e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs3008870 0.959 rs2815359 chr1:67494374 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.35 0.66 8.35e-45 Lymphocyte percentage of white cells; LIHC cis rs7208859 0.673 rs8077116 chr17:29140162 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1577917 0.771 rs7742201 chr6:86432930 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.48 -8.29 -0.41 2.7e-15 Response to antipsychotic treatment; LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg14004847 chr7:1930337 MAD1L1 -0.47 -6.96 -0.35 1.79e-11 Bipolar disorder and schizophrenia; LIHC cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg21951975 chr1:209979733 IRF6 0.42 6.64 0.34 1.23e-10 Cleft lip with or without cleft palate; LIHC cis rs5769765 1.000 rs8184990 chr22:50273174 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs9640161 0.659 rs7781827 chr7:150008858 T/C cg21361702 chr7:150065534 REPIN1 0.48 6.54 0.33 2.26e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs12887734 0.546 rs12886637 chr14:104222892 A/G cg01849466 chr14:104193079 ZFYVE21 0.4 6.03 0.31 4.22e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs5769707 0.740 rs79946167 chr22:50017556 G/A cg07959070 chr22:50026188 C22orf34 -0.26 -6.68 -0.34 9.87e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2842992 0.750 rs2758354 chr6:160125854 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.73 12.76 0.57 8.76e-31 Age-related macular degeneration (geographic atrophy); LIHC cis rs1008375 0.966 rs1860599 chr4:17638900 T/C cg16339924 chr4:17578868 LAP3 0.44 6.21 0.32 1.5e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs74233809 1.000 rs10509759 chr10:104689665 A/T cg03493300 chr10:104813866 CNNM2 0.47 6.15 0.32 2.16e-9 Birth weight; LIHC cis rs6951245 0.608 rs10252234 chr7:1114381 C/T cg24642844 chr7:1081250 C7orf50 -0.52 -6.52 -0.33 2.51e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2742417 0.624 rs2673030 chr3:45757900 T/G cg04837898 chr3:45731254 SACM1L -0.53 -8.87 -0.43 4.05e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs66573146 0.572 rs67922134 chr4:6955772 G/A cg15105060 chr4:7024189 TBC1D14 -0.68 -6.1 -0.31 2.88e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs769267 0.501 rs2965187 chr19:19522970 T/A cg10763598 chr19:19431466 KIAA0892;SF4 0.58 6.49 0.33 3.01e-10 Tonsillectomy; LIHC cis rs796364 0.951 rs971232 chr2:200792881 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.16 0.44 4.71e-18 Schizophrenia; LIHC cis rs1008375 0.835 rs9760627 chr4:17651508 C/T cg16339924 chr4:17578868 LAP3 0.41 5.87 0.3 1.05e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9818758 0.607 rs12715434 chr3:49295025 G/C cg06212747 chr3:49208901 KLHDC8B -0.66 -5.87 -0.3 1.01e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9768139 0.634 rs56389048 chr7:158121368 T/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.93 -0.31 7.29e-9 Calcium levels; LIHC cis rs17095355 1.000 rs11194917 chr10:111692552 C/G cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.77 -0.3 1.82e-8 Biliary atresia; LIHC cis rs2952156 0.920 rs11078919 chr17:37835755 T/C cg00129232 chr17:37814104 STARD3 -0.53 -10.31 -0.49 6.79e-22 Asthma; LIHC cis rs11971779 0.680 rs6954547 chr7:139054734 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg22963979 chr7:1858916 MAD1L1 -0.45 -7.19 -0.36 4.23e-12 Bipolar disorder and schizophrenia; LIHC cis rs10876993 0.784 rs7314152 chr12:58017701 T/G cg15848620 chr12:58087721 OS9 0.5 6.38 0.33 5.68e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs10791097 0.694 rs876641 chr11:130752040 A/C cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 4.09e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs8077889 0.871 rs72836549 chr17:41904360 G/T cg26893861 chr17:41843967 DUSP3 0.99 10.76 0.5 1.9e-23 Triglycerides; LIHC cis rs7208859 0.673 rs9911989 chr17:29237702 A/C cg13385521 chr17:29058706 SUZ12P -0.8 -7.85 -0.39 5.25e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 7.26 0.37 2.61e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs67478160 0.654 rs1997913 chr14:104213960 C/T cg01849466 chr14:104193079 ZFYVE21 -0.47 -7.65 -0.38 2e-13 Schizophrenia; LIHC cis rs74181299 0.712 rs2241160 chr2:65291546 A/G cg05010058 chr2:65284262 CEP68 0.36 6.38 0.33 5.72e-10 Pulse pressure; LIHC cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg06481639 chr22:41940642 POLR3H -0.66 -6.54 -0.33 2.23e-10 Vitiligo; LIHC cis rs11958404 0.546 rs7727054 chr5:157442692 G/A cg05962755 chr5:157440814 NA 0.63 8.24 0.41 3.77e-15 IgG glycosylation; LIHC cis rs870825 0.929 rs55635512 chr4:185589982 G/T cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg23758822 chr17:41437982 NA 0.94 17.56 0.69 1.21e-49 Menopause (age at onset); LIHC cis rs651907 0.535 rs13094753 chr3:101525082 A/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC cis rs2204008 0.775 rs12369238 chr12:38176051 A/G cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC cis rs7116495 1.000 rs656640 chr11:71781710 T/C cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg15586393 chr4:1244086 CTBP1;C4orf42 -0.44 -6.23 -0.32 1.37e-9 Longevity; LIHC trans rs78049276 0.568 rs10305839 chr4:148400413 C/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.57 -7.47 -0.37 6.61e-13 Pulse pressure; LIHC cis rs4268898 0.828 rs2702121 chr2:24610392 C/A cg06627628 chr2:24431161 ITSN2 0.55 7.57 0.38 3.5e-13 Asthma; LIHC cis rs1570884 0.516 rs9535268 chr13:50175478 C/A cg08779649 chr13:50194554 NA 0.35 6.41 0.33 4.78e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs765787 0.530 rs11634794 chr15:45534492 A/C cg25801113 chr15:45476975 SHF 0.38 6.55 0.33 2.1e-10 Uric acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15254786 chr2:207630414 MDH1B;FASTKD2 0.43 6.19 0.32 1.76e-9 Pancreatic cancer; LIHC cis rs2806561 0.765 rs643492 chr1:23501354 C/T cg12483005 chr1:23474871 LUZP1 -0.47 -7.48 -0.37 6.31e-13 Height; LIHC cis rs7659604 0.628 rs6838153 chr4:122720999 A/G cg19748678 chr4:122722346 EXOSC9 0.67 11.04 0.51 1.99e-24 Type 2 diabetes; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg00626518 chr5:10441665 ROPN1L -0.42 -6.04 -0.31 4.03e-9 Eotaxin levels; LIHC trans rs10411161 0.752 rs9973239 chr19:52406779 C/T cg22319618 chr22:45562946 NUP50 -0.5 -6.55 -0.33 2.13e-10 Breast cancer; LIHC cis rs2302190 0.882 rs7226008 chr17:56644633 T/C cg12560992 chr17:57184187 TRIM37 0.68 8.8 0.43 7e-17 Vitamin D levels; LIHC cis rs317689 0.613 rs315112 chr12:69785926 T/A cg19645103 chr12:69753606 YEATS4 -0.52 -7.86 -0.39 5.06e-14 Response to diuretic therapy; LIHC cis rs7771547 0.607 rs6923993 chr6:36427276 A/G cg07856975 chr6:36356162 ETV7 0.35 5.78 0.3 1.69e-8 Platelet distribution width; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13619988 chr14:58894515 KIAA0586;TIMM9 0.51 7.46 0.37 7.3e-13 Cognitive function; LIHC cis rs7927771 0.864 rs112060627 chr11:47426956 G/A cg20307385 chr11:47447363 PSMC3 -0.48 -6.28 -0.32 1.03e-9 Subjective well-being; LIHC cis rs11628318 0.570 rs2896450 chr14:103076595 T/C cg23461800 chr14:103021989 NA -0.43 -5.88 -0.3 9.57e-9 Platelet count; LIHC cis rs2439831 1.000 rs2245054 chr15:43751909 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.96 0.44 2.2e-17 Lung cancer in ever smokers; LIHC cis rs782590 0.764 rs935177 chr2:55826761 C/G cg18811423 chr2:55921094 PNPT1 0.79 11.65 0.53 1.22e-26 Metabolic syndrome; LIHC cis rs1552244 0.572 rs73117481 chr3:10160132 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg24209194 chr3:40518798 ZNF619 0.56 8.12 0.4 8.67e-15 Renal cell carcinoma; LIHC cis rs2180341 0.804 rs6902233 chr6:127555963 A/G cg24812749 chr6:127587940 RNF146 0.98 12.81 0.57 5.69e-31 Breast cancer; LIHC cis rs875971 0.893 rs62465470 chr7:65601218 T/C cg11764359 chr7:65958608 NA -0.82 -13.79 -0.6 1.02e-34 Aortic root size; LIHC cis rs1113500 0.862 rs11185264 chr1:108640506 T/C cg06207961 chr1:108661230 NA 0.37 7.24 0.36 3.02e-12 Growth-regulated protein alpha levels; LIHC trans rs2739330 0.828 rs2330635 chr22:24251344 T/C cg06437703 chr8:37914619 EIF4EBP1 -0.52 -7.9 -0.39 3.79e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs28676615 chr21:46676576 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.58 0.53 2.2e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09133192 chr4:89205337 PPM1K 0.47 6.34 0.32 7.23e-10 Pancreatic cancer; LIHC cis rs1941023 0.503 rs4939348 chr11:60135871 A/C cg08716584 chr11:60157161 MS4A7 -0.35 -8.13 -0.4 8e-15 Congenital heart disease (maternal effect); LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg07133347 chr1:107600762 PRMT6 -0.45 -6.73 -0.34 6.96e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9303280 0.773 rs11078925 chr17:38025208 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.84 0.3 1.19e-8 Self-reported allergy; LIHC cis rs9916302 0.904 rs8066704 chr17:37477218 C/T cg07936489 chr17:37558343 FBXL20 0.84 13.66 0.59 3.37e-34 Glomerular filtration rate (creatinine); LIHC cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg23758822 chr17:41437982 NA 0.93 17.76 0.69 1.75e-50 Menopause (age at onset); LIHC cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg08219700 chr8:58056026 NA 0.55 6.72 0.34 7.75e-11 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg16145915 chr7:1198662 ZFAND2A -0.34 -8.4 -0.41 1.21e-15 Longevity;Endometriosis; LIHC cis rs765787 0.530 rs28414644 chr15:45536721 G/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.74 -0.3 2.06e-8 Uric acid levels; LIHC cis rs700651 0.789 rs62277902 chr2:198879443 T/A cg03934865 chr2:198174659 NA -0.46 -6.63 -0.34 1.32e-10 Intracranial aneurysm; LIHC cis rs3796352 0.568 rs11713376 chr3:52958927 A/G cg07884673 chr3:53033167 SFMBT1 0.76 6.02 0.31 4.5e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs4665809 0.838 rs7565843 chr2:26292912 G/C cg04944784 chr2:26401820 FAM59B -0.69 -8.69 -0.43 1.55e-16 Gut microbiome composition (summer); LIHC cis rs2346177 0.580 rs7565770 chr2:46683683 A/C cg02822958 chr2:46747628 ATP6V1E2 0.33 6.06 0.31 3.5e-9 HDL cholesterol; LIHC cis rs4925386 0.819 rs2890083 chr20:60911958 G/A cg06026331 chr20:60912101 LAMA5 -0.45 -7.43 -0.37 8.9e-13 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7172677 0.793 rs8029712 chr15:75418170 T/A cg09165964 chr15:75287851 SCAMP5 -0.42 -5.87 -0.3 1.01e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs780094 0.544 rs780108 chr2:27684957 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.46 -6.99 -0.35 1.47e-11 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs10916814 0.589 rs7416238 chr1:20897240 A/G cg24502330 chr1:20914028 CDA -0.31 -6.76 -0.34 6.01e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs13108904 0.901 rs7695691 chr4:1304632 A/G cg20887711 chr4:1340912 KIAA1530 0.6 9.5 0.46 3.88e-19 Obesity-related traits; LIHC cis rs12477438 0.520 rs720229 chr2:99704273 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.61 9.75 0.47 5.54e-20 Chronic sinus infection; LIHC cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg18357526 chr6:26021779 HIST1H4A -0.53 -7.15 -0.36 5.44e-12 Blood metabolite levels; LIHC cis rs4407350 0.715 rs3827400 chr22:44890604 T/C cg26276947 chr22:44892394 LDOC1L 0.33 6.19 0.32 1.69e-9 Intelligence (multi-trait analysis); LIHC cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg25364880 chr3:44379878 C3orf23 0.5 7.19 0.36 4.22e-12 Depressive symptoms; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg05052194 chr1:2160249 SKI 0.43 6.18 0.32 1.85e-9 Migraine with aura; LIHC cis rs74417235 0.684 rs13185173 chr5:154055081 A/G cg19735590 chr5:154026979 NA 0.47 5.73 0.3 2.22e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs12368653 0.701 rs238517 chr12:58117737 T/G cg12615879 chr12:58013172 SLC26A10 0.33 6.6 0.34 1.53e-10 Multiple sclerosis; LIHC cis rs1511802 0.501 rs7661323 chr4:187115996 T/G cg24794857 chr4:187113578 CYP4V2 0.37 5.88 0.3 9.86e-9 Blood protein levels; LIHC cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg11987759 chr7:65425863 GUSB 0.38 6.06 0.31 3.61e-9 Calcium levels; LIHC cis rs8077889 1.000 rs2066725 chr17:41891473 A/G cg26893861 chr17:41843967 DUSP3 0.95 11.11 0.51 1.12e-24 Triglycerides; LIHC cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg08888203 chr3:10149979 C3orf24 0.58 6.82 0.35 4.03e-11 Alzheimer's disease; LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg07157834 chr1:205819609 PM20D1 0.67 10.06 0.48 4.98e-21 Menarche (age at onset); LIHC cis rs3096299 0.566 rs4129126 chr16:89561475 A/C cg06640241 chr16:89574553 SPG7 0.62 9.08 0.44 8.69e-18 Multiple myeloma (IgH translocation); LIHC cis rs933688 0.877 rs10474352 chr5:90732225 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 15.86 0.65 7.41e-43 Smoking behavior; LIHC cis rs1152591 0.967 rs1152589 chr14:64683926 A/T cg21174375 chr14:64681225 SYNE2 -0.39 -6.09 -0.31 3.09e-9 Atrial fibrillation; LIHC cis rs12644436 0.615 rs4416441 chr4:88776233 A/G cg06891869 chr4:88767617 MEPE 0.43 7.64 0.38 2.2e-13 HIV-1 viral setpoint; LIHC cis rs2204008 0.754 rs11181643 chr12:38380553 G/A cg26384229 chr12:38710491 ALG10B 0.6 8.36 0.41 1.56e-15 Bladder cancer; LIHC cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg02290350 chr8:58132656 NA 0.48 9.52 0.46 3.28e-19 Developmental language disorder (linguistic errors); LIHC cis rs7412746 0.658 rs17660092 chr1:150797748 T/C cg17724175 chr1:150552817 MCL1 0.48 9.63 0.46 1.44e-19 Melanoma; LIHC cis rs887797 0.538 rs6504444 chr17:64579751 A/G cg27019712 chr17:64599478 PRKCA -0.39 -6.71 -0.34 8.12e-11 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC cis rs3849570 0.925 rs1464791 chr3:81893929 A/C cg07356753 chr3:81810745 GBE1 0.54 8.45 0.42 8.75e-16 Waist circumference;Body mass index; LIHC cis rs36051895 0.623 rs7035456 chr9:5261440 G/A cg02405213 chr9:5042618 JAK2 -0.57 -9.29 -0.45 1.91e-18 Pediatric autoimmune diseases; LIHC cis rs2742417 0.603 rs2064064 chr3:45759995 C/T cg04837898 chr3:45731254 SACM1L -0.52 -8.67 -0.42 1.75e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs1046896 0.553 rs56775875 chr17:80831291 G/T cg19500275 chr17:80737654 TBCD 0.41 5.76 0.3 1.86e-8 Glycated hemoglobin levels; LIHC cis rs4423214 0.921 rs11603330 chr11:71153459 C/A cg05163923 chr11:71159392 DHCR7 0.93 14.46 0.62 2.67e-37 Vitamin D levels; LIHC cis rs12497850 0.931 rs7636057 chr3:48992582 C/T cg07636037 chr3:49044803 WDR6 0.92 16.54 0.67 1.44e-45 Parkinson's disease; LIHC cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg05564831 chr3:52568323 NT5DC2 0.35 5.92 0.3 7.89e-9 Electroencephalogram traits; LIHC cis rs6089829 0.962 rs9680064 chr20:61666168 G/A cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs17102423 0.623 rs2093989 chr14:65553939 C/T cg11161011 chr14:65562177 MAX -0.41 -6.22 -0.32 1.42e-9 Obesity-related traits; LIHC cis rs1451375 1.000 rs10250513 chr7:50621488 T/G cg14593290 chr7:50529359 DDC 0.4 6.65 0.34 1.18e-10 Malaria; LIHC cis rs6450176 0.909 rs80213371 chr5:53300874 T/G ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.6 -0.62 7.2e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs7659604 0.502 rs4075066 chr4:122684283 T/C cg19671926 chr4:122722719 EXOSC9 0.55 8.49 0.42 6.41e-16 Type 2 diabetes; LIHC trans rs4942242 0.626 rs7986998 chr13:44209916 G/A cg19169023 chr15:41853346 TYRO3 0.51 7.28 0.37 2.38e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs921968 0.643 rs864990 chr2:219494037 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.15 0.32 2.12e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7027203 0.828 rs4743934 chr9:96581893 A/G cg14598338 chr9:96623480 NA -0.32 -6.43 -0.33 4.29e-10 DNA methylation (variation); LIHC cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg11644478 chr21:40555479 PSMG1 0.74 9.22 0.45 3.14e-18 Cognitive function; LIHC cis rs7726839 0.561 rs6555357 chr5:560923 A/G cg09021430 chr5:549028 NA -0.39 -8.51 -0.42 5.36e-16 Obesity-related traits; LIHC cis rs743757 1.000 rs1107265 chr3:50431995 A/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.47 6.74 0.34 6.8e-11 Diastolic blood pressure; LIHC cis rs7552404 0.924 rs1146579 chr1:76209792 C/T cg03433033 chr1:76189801 ACADM -0.65 -9.86 -0.47 2.36e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs847649 0.961 rs10250490 chr7:102537277 A/G cg18108683 chr7:102477205 FBXL13 -0.48 -7.09 -0.36 7.8e-12 Morning vs. evening chronotype; LIHC cis rs36051895 0.623 rs7027871 chr9:5236822 C/G cg02405213 chr9:5042618 JAK2 0.65 10.76 0.5 1.96e-23 Pediatric autoimmune diseases; LIHC cis rs9457247 0.534 rs7750593 chr6:167387359 C/G cg12798992 chr6:167411361 FGFR1OP -0.48 -7.76 -0.39 1.02e-13 Crohn's disease; LIHC cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Bipolar disorder; LIHC cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg05590025 chr7:65112418 INTS4L2 0.61 6.78 0.34 5.22e-11 Diabetic kidney disease; LIHC cis rs611744 0.647 rs1609472 chr8:109269232 T/G cg21045802 chr8:109455806 TTC35 0.58 10.31 0.49 6.89e-22 Dupuytren's disease; LIHC cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg06453172 chr10:134556979 INPP5A -0.63 -8.49 -0.42 6.37e-16 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg09704166 chr2:114031854 PAX8;LOC440839 -0.33 -5.73 -0.3 2.2e-8 Lymphocyte counts; LIHC cis rs722599 0.748 rs59112602 chr14:75358817 C/G cg11812906 chr14:75593930 NEK9 -0.46 -7.28 -0.37 2.32e-12 IgG glycosylation; LIHC cis rs11148252 0.564 rs2296350 chr13:52710044 T/C cg00495681 chr13:53174319 NA 0.39 6.71 0.34 8.13e-11 Lewy body disease; LIHC cis rs894734 0.567 rs7138907 chr12:54324576 C/T cg17410650 chr12:54324560 NA -0.42 -8.3 -0.41 2.43e-15 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs2257205 0.667 rs78253932 chr17:56804101 C/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.67 -0.34 1e-10 Pancreatic cancer; LIHC cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg02931644 chr1:25747376 RHCE -0.37 -8.22 -0.41 4.26e-15 Erythrocyte sedimentation rate; LIHC cis rs12477438 0.798 rs9308816 chr2:99637230 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.68 -0.53 9.29e-27 Chronic sinus infection; LIHC cis rs1707322 0.506 rs2991983 chr1:46079391 T/C cg06784218 chr1:46089804 CCDC17 -0.42 -7.45 -0.37 7.48e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9326778 0.520 rs60417058 chr5:108842205 G/A cg17395555 chr5:108820864 NA -0.37 -6.41 -0.33 4.88e-10 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs738322 0.967 rs133024 chr22:38574066 C/T cg17652424 chr22:38574118 PLA2G6 0.19 6.05 0.31 3.87e-9 Cutaneous nevi; LIHC cis rs9420 0.961 rs708228 chr11:57585662 C/T cg19752551 chr11:57585705 CTNND1 -0.51 -7.16 -0.36 5.11e-12 Schizophrenia; LIHC cis rs6583826 0.538 rs11187076 chr10:94336963 G/A cg25506282 chr10:94462361 NA 0.37 6.38 0.33 5.64e-10 Type 2 diabetes; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08585897 chr16:75680535 KARS;TERF2IP 0.48 6.68 0.34 9.66e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10504229 0.871 rs10504227 chr8:58162005 G/A cg02290350 chr8:58132656 NA 0.4 8.56 0.42 4.01e-16 Developmental language disorder (linguistic errors); LIHC cis rs8078723 0.690 rs3785549 chr17:38149724 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.35 0.52 1.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.52 0.53 3.75e-26 Colorectal cancer; LIHC cis rs2976388 0.609 rs1560986 chr8:143789775 T/C cg06565975 chr8:143823917 SLURP1 0.33 6.28 0.32 1.01e-9 Urinary tract infection frequency; LIHC cis rs9318086 0.648 rs78881146 chr13:24468704 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.56 10.67 0.5 3.88e-23 Myopia (pathological); LIHC cis rs2834256 0.527 rs9983905 chr21:34866858 C/T cg14850771 chr21:34775459 IFNGR2 0.47 7.77 0.39 9.31e-14 Red cell distribution width; LIHC cis rs7551222 0.752 rs10900597 chr1:204522489 C/T cg20240347 chr1:204465584 NA -0.34 -7.13 -0.36 5.86e-12 Schizophrenia; LIHC cis rs11122272 0.735 rs2486730 chr1:231534987 T/G cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.73e-19 Hemoglobin concentration; LIHC cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg00149659 chr3:10157352 C3orf10 0.6 6.62 0.34 1.36e-10 Alzheimer's disease; LIHC trans rs75804782 0.581 rs72987336 chr2:239365345 T/C cg01134436 chr17:81009848 B3GNTL1 0.86 7.21 0.36 3.6e-12 Morning vs. evening chronotype;Chronotype; LIHC cis rs13118159 0.801 rs7690727 chr4:1340811 C/A cg13395646 chr4:1353034 KIAA1530 -0.65 -8.8 -0.43 7.08e-17 Longevity; LIHC cis rs72781680 0.611 rs72797819 chr2:24351141 T/G cg06627628 chr2:24431161 ITSN2 -0.62 -7.31 -0.37 1.88e-12 Lymphocyte counts; LIHC cis rs3106136 0.967 rs2087170 chr4:95162960 A/C cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.62 -0.38 2.56e-13 Capecitabine sensitivity; LIHC cis rs9309473 1.000 rs6755241 chr2:73641364 C/T cg20560298 chr2:73613845 ALMS1 -0.55 -6.25 -0.32 1.22e-9 Metabolite levels; LIHC cis rs7618501 0.966 rs9882639 chr3:49799475 A/C cg21467203 chr3:49911342 NA -0.41 -7.07 -0.36 9e-12 Intelligence (multi-trait analysis); LIHC cis rs875971 1.000 rs778694 chr7:65871558 A/G cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs10876993 0.928 rs1689587 chr12:58075398 A/G cg18357645 chr12:58087776 OS9 0.53 8.7 0.43 1.41e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs7818688 0.653 rs11775475 chr8:95905489 T/G cg16049864 chr8:95962084 TP53INP1 0.56 5.76 0.3 1.88e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7395581 0.918 rs1052373 chr11:47354787 A/G cg26139080 chr11:47293733 MADD 0.51 8.51 0.42 5.72e-16 HDL cholesterol; LIHC cis rs10493773 0.962 rs6698578 chr1:86236676 G/A cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.32 -0.37 1.83e-12 Urate levels in overweight individuals; LIHC cis rs9457247 0.624 rs9457260 chr6:167466665 C/T cg07741184 chr6:167504864 NA 0.35 8.22 0.41 4.17e-15 Crohn's disease; LIHC cis rs3020736 0.500 rs6002604 chr22:42493081 A/T cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs965469 1.000 rs6051672 chr20:3224819 C/T cg25506879 chr20:3388711 C20orf194 -0.59 -6.8 -0.35 4.69e-11 IFN-related cytopenia; LIHC cis rs12477438 0.765 rs2167930 chr2:99592551 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.06 -14.67 -0.62 3.78e-38 Chronic sinus infection; LIHC cis rs6840360 0.571 rs62327274 chr4:152548012 C/T cg22705602 chr4:152727874 NA -0.34 -6.45 -0.33 3.83e-10 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg21782813 chr7:2030301 MAD1L1 0.43 7.02 0.36 1.17e-11 Bipolar disorder and schizophrenia; LIHC cis rs35110281 0.837 rs2838343 chr21:45078035 C/T cg21573476 chr21:45109991 RRP1B -0.51 -9.63 -0.46 1.44e-19 Mean corpuscular volume; LIHC cis rs3768617 0.510 rs20563 chr1:183085755 C/T ch.1.3577855R chr1:183094577 LAMC1 -0.59 -10.56 -0.5 9.78e-23 Fuchs's corneal dystrophy; LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.13e-9 Menopause (age at onset); LIHC cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg16405210 chr4:1374714 KIAA1530 -0.64 -9.71 -0.46 7.59e-20 Longevity; LIHC cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg21448741 chr8:58168803 NA 0.36 5.91 0.3 8.43e-9 Developmental language disorder (linguistic errors); LIHC cis rs7613875 0.641 rs6793528 chr3:50100188 C/A cg21467203 chr3:49911342 NA 0.52 9.35 0.45 1.18e-18 Body mass index; LIHC cis rs782590 0.902 rs782601 chr2:55848244 T/C cg03859395 chr2:55845619 SMEK2 0.9 15.68 0.65 3.88e-42 Metabolic syndrome; LIHC cis rs4788570 0.566 rs72795867 chr16:71484465 A/G cg06353428 chr16:71660113 MARVELD3 -1.12 -10.11 -0.48 3.28e-21 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC trans rs801193 1.000 rs2003301 chr7:66147656 G/C cg26939375 chr7:64535504 NA -0.42 -6.77 -0.34 5.53e-11 Aortic root size; LIHC cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.09 0.31 2.96e-9 Menopause (age at onset); LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.3 0.37 1.98e-12 Height; LIHC cis rs4908768 0.520 rs11121224 chr1:8773515 A/G cg20416874 chr1:8611966 RERE -0.63 -11.43 -0.53 7.67e-26 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1003719 0.680 rs7276569 chr21:38578207 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg21782813 chr7:2030301 MAD1L1 0.43 7.09 0.36 7.73e-12 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13128305 chr8:95961759 TP53INP1 -0.41 -6.22 -0.32 1.41e-9 Pancreatic cancer; LIHC cis rs6570726 0.689 rs411785 chr6:145888398 G/A cg23711669 chr6:146136114 FBXO30 0.75 13.53 0.59 1.05e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs11673344 0.734 rs1644638 chr19:37461415 C/A cg27390819 chr19:37464633 NA -0.53 -6.29 -0.32 9.74e-10 Obesity-related traits; LIHC cis rs6831352 0.879 rs34360292 chr4:100051303 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7131987 0.801 rs6487804 chr12:29454934 G/A cg14222432 chr12:29376421 FAR2 0.36 7.2 0.36 3.95e-12 QT interval; LIHC cis rs12586317 0.547 rs4982234 chr14:35460106 T/A cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.04e-32 Psoriasis; LIHC trans rs10506458 1.000 rs73127086 chr12:63415626 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.72 -10.41 -0.49 3.17e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs1153858 1.000 rs9783731 chr15:45642884 C/T cg21132104 chr15:45694354 SPATA5L1 -0.44 -7.15 -0.36 5.21e-12 Homoarginine levels; LIHC cis rs826838 0.510 rs10876149 chr12:39228083 C/G cg26384229 chr12:38710491 ALG10B -0.53 -7.12 -0.36 6.25e-12 Heart rate; LIHC cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg03806693 chr22:41940476 POLR3H -1.07 -12.24 -0.55 7.79e-29 Vitiligo; LIHC cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg27170947 chr2:26402098 FAM59B -0.66 -8.24 -0.41 3.72e-15 Gut microbiome composition (summer); LIHC cis rs875971 0.660 rs1860468 chr7:66107252 T/C cg11764359 chr7:65958608 NA -0.64 -9.25 -0.45 2.55e-18 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10624105 chr20:48729304 UBE2V1;TMEM189-UBE2V1 0.46 6.81 0.35 4.48e-11 Pancreatic cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08676730 chr17:53828263 PCTP -0.5 -6.04 -0.31 4.02e-9 Systolic blood pressure; LIHC cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg09025071 chr16:1593152 IFT140;TMEM204 0.34 6.72 0.34 7.68e-11 Coronary artery disease; LIHC cis rs2404602 0.647 rs10851892 chr15:77176491 T/C cg23625390 chr15:77176239 SCAPER -0.54 -8.84 -0.43 5.21e-17 Blood metabolite levels; LIHC cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg00149659 chr3:10157352 C3orf10 0.69 7.29 0.37 2.18e-12 Alzheimer's disease; LIHC cis rs2073300 0.609 rs1076776 chr20:23427399 C/T cg16736954 chr20:23401023 NAPB -0.7 -8.31 -0.41 2.21e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs11014306 1.000 rs7084900 chr10:25201585 G/A cg17214381 chr4:188916668 ZFP42 -0.55 -6.24 -0.32 1.29e-9 Metabolite levels (Pyroglutamine); LIHC cis rs798554 0.679 rs1636253 chr7:2885123 A/G cg13628971 chr7:2884303 GNA12 0.6 10.06 0.48 4.97e-21 Height; LIHC cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.8 0.3 1.54e-8 Menopause (age at onset); LIHC cis rs10540 1.000 rs12421457 chr11:505780 T/C cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.71e-15 Body mass index; LIHC cis rs4665809 0.878 rs4665826 chr2:26367503 A/T cg27170947 chr2:26402098 FAM59B 0.7 8.73 0.43 1.16e-16 Gut microbiome composition (summer); LIHC cis rs6952808 0.531 rs3778998 chr7:2180753 C/A cg04267008 chr7:1944627 MAD1L1 -0.5 -7.69 -0.38 1.56e-13 Bipolar disorder and schizophrenia; LIHC cis rs2439831 0.717 rs2447198 chr15:43895118 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.62 7.45 0.37 7.65e-13 Lung cancer in ever smokers; LIHC cis rs208520 0.690 rs9345764 chr6:66820597 C/T cg07460842 chr6:66804631 NA -0.87 -9.38 -0.45 9.07e-19 Exhaled nitric oxide output; LIHC cis rs317689 0.918 rs689415 chr12:69738139 A/G cg20891283 chr12:69753455 YEATS4 -0.66 -10.33 -0.49 6.06e-22 Response to diuretic therapy; LIHC cis rs13118159 0.801 rs1128427 chr4:1330759 T/C cg20887711 chr4:1340912 KIAA1530 0.46 6.59 0.34 1.65e-10 Longevity; LIHC cis rs9916302 0.904 rs2338800 chr17:37498149 C/G cg03013999 chr17:37608204 MED1 -0.36 -5.91 -0.3 8.49e-9 Glomerular filtration rate (creatinine); LIHC cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg03264133 chr6:25882463 NA -0.48 -7.26 -0.37 2.67e-12 Height; LIHC cis rs1059312 1.000 rs7135854 chr12:129279988 G/C cg09035930 chr12:129282057 SLC15A4 0.69 13.29 0.58 8.71e-33 Systemic lupus erythematosus; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14134019 chr9:90140250 DAPK1 0.41 6.53 0.33 2.32e-10 Bilirubin levels; LIHC cis rs6977660 1.000 rs6959591 chr7:19821824 A/G cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs9378688 0.546 rs9405548 chr6:2208409 G/A cg12303981 chr6:2244766 GMDS -0.46 -6.19 -0.32 1.68e-9 Caudate nucleus volume; LIHC cis rs9303401 0.592 rs66583824 chr17:56639853 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs9918079 0.560 rs10008376 chr4:15623955 A/G cg21123203 chr4:15471301 CC2D2A 0.43 6.95 0.35 1.83e-11 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25219047 chr19:3500813 DOHH 0.43 6.44 0.33 4.08e-10 Pancreatic cancer; LIHC cis rs12887734 0.524 rs17791722 chr14:104286210 C/T cg08213375 chr14:104286397 PPP1R13B 0.53 9.11 0.44 6.83e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs12497850 0.931 rs7431710 chr3:48935583 G/A cg07636037 chr3:49044803 WDR6 0.91 16.39 0.66 5.92e-45 Parkinson's disease; LIHC cis rs2933343 1.000 rs789232 chr3:128603080 T/G cg25356066 chr3:128598488 ACAD9 0.54 7.21 0.36 3.57e-12 IgG glycosylation; LIHC cis rs763121 0.819 rs6001205 chr22:39100264 T/A cg06022373 chr22:39101656 GTPBP1 0.65 11.2 0.52 5.34e-25 Menopause (age at onset); LIHC cis rs9303401 0.538 rs35454383 chr17:56475599 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.93 12.13 0.55 2.13e-28 Cognitive test performance; LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg04013166 chr16:89971882 TCF25 0.55 7.23 0.36 3.16e-12 Skin colour saturation; LIHC cis rs875971 1.000 rs778699 chr7:65868290 G/A cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs6546550 0.901 rs6739780 chr2:70138111 G/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC cis rs10876993 0.890 rs812304 chr12:58074853 A/C cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.16 -0.32 2.06e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.54e-18 Bipolar disorder; LIHC cis rs1552244 0.572 rs7645667 chr3:10157337 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 8.89 0.43 3.52e-17 Alzheimer's disease; LIHC cis rs6539267 0.741 rs2279759 chr12:106694988 T/C cg02476566 chr12:106696527 TCP11L2 0.46 6.16 0.32 2.01e-9 Tourette syndrome; LIHC cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg20607798 chr8:58055168 NA 0.49 6.13 0.31 2.37e-9 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg13271783 chr10:134563150 INPP5A -0.54 -6.61 -0.34 1.47e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg19635926 chr16:89946313 TCF25 -0.52 -7.08 -0.36 8.23e-12 Skin colour saturation; LIHC cis rs2404602 0.692 rs57178708 chr15:76904069 T/C cg03037974 chr15:76606532 NA 0.74 14.42 0.62 3.55e-37 Blood metabolite levels; LIHC cis rs526821 0.789 rs10896993 chr11:55303410 A/G cg04317927 chr11:55418816 OR4S2 0.42 8.21 0.41 4.54e-15 Pediatric bone mineral density (spine); LIHC cis rs10751667 0.621 rs11246345 chr11:934924 T/C cg10932868 chr11:921992 NA 0.38 7.32 0.37 1.83e-12 Alzheimer's disease (late onset); LIHC cis rs1552244 0.882 rs34706481 chr3:10004123 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.58 -8.23 -0.41 3.91e-15 Alzheimer's disease; LIHC cis rs1949733 1.000 rs2631740 chr4:8484106 C/A cg11789530 chr4:8429930 ACOX3 -0.81 -11.89 -0.54 1.57e-27 Response to antineoplastic agents; LIHC cis rs2050392 0.799 rs2907 chr10:30728250 A/G cg25182066 chr10:30743637 MAP3K8 -0.48 -7.93 -0.39 3.23e-14 Inflammatory bowel disease; LIHC cis rs4638749 0.677 rs13389470 chr2:108806301 C/G cg25838818 chr2:108905173 SULT1C2 -0.38 -6.82 -0.35 4.26e-11 Blood pressure; LIHC cis rs6952808 0.531 rs3800922 chr7:2184505 A/G cg02951883 chr7:2050386 MAD1L1 -0.62 -9.97 -0.47 9.8e-21 Bipolar disorder and schizophrenia; LIHC cis rs79387448 0.655 rs79144324 chr2:102932814 G/A cg09003973 chr2:102972529 NA 1.22 9.96 0.47 1.14e-20 Gut microbiota (bacterial taxa); LIHC cis rs6586163 0.527 rs3740286 chr10:90751340 A/G cg03111039 chr10:90751583 FAS;ACTA2 0.8 12.79 0.57 7e-31 Chronic lymphocytic leukemia; LIHC cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg07414643 chr4:187882934 NA 0.24 6.09 0.31 3.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg12310025 chr6:25882481 NA -0.64 -9.06 -0.44 9.89e-18 Blood metabolite levels; LIHC cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg11890956 chr21:40555474 PSMG1 -0.48 -7.82 -0.39 6.61e-14 Cognitive function; LIHC cis rs3784262 0.669 rs4646597 chr15:58300768 G/A cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.75 -0.3 2.01e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs526231 0.819 rs35801 chr5:102608213 G/T cg05225461 chr5:102596755 C5orf30 0.37 5.75 0.3 1.98e-8 Primary biliary cholangitis; LIHC cis rs2963155 0.518 rs2963151 chr5:142734151 T/C cg17617527 chr5:142782415 NR3C1 0.85 10.05 0.48 5.4e-21 Breast cancer; LIHC cis rs2243480 0.901 rs778730 chr7:65823325 T/A cg12463550 chr7:65579703 CRCP 0.65 6.8 0.35 4.56e-11 Diabetic kidney disease; LIHC cis rs6430585 0.583 rs79633114 chr2:136586825 C/T cg07169764 chr2:136633963 MCM6 1.34 20.4 0.74 4.42e-61 Corneal structure; LIHC cis rs1552244 0.816 rs56271597 chr3:10042790 C/T cg00149659 chr3:10157352 C3orf10 0.53 6.03 0.31 4.28e-9 Alzheimer's disease; LIHC cis rs9534288 0.700 rs4942466 chr13:46597190 A/G cg15192986 chr13:46630673 CPB2 -0.48 -7.28 -0.37 2.34e-12 Blood protein levels; LIHC cis rs12474201 0.832 rs35722922 chr2:47002226 A/G cg06386533 chr2:46925753 SOCS5 0.6 6.43 0.33 4.25e-10 Height; LIHC cis rs3820500 0.543 rs1290553 chr1:118056073 G/T cg20383390 chr1:117909022 MAN1A2 -0.45 -5.8 -0.3 1.48e-8 Pneumonia; LIHC cis rs4908768 0.906 rs10492965 chr1:8598127 G/A cg25722041 chr1:8623473 RERE 0.42 6.01 0.31 4.7e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs754466 0.580 rs10824573 chr10:79540969 T/C cg17075019 chr10:79541650 NA -0.79 -12.22 -0.55 9.41e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6570726 0.935 rs447818 chr6:145868996 C/T cg23711669 chr6:146136114 FBXO30 0.53 9.18 0.44 4.13e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs11671005 0.779 rs55875034 chr19:58983558 T/G cg25952890 chr19:58913133 NA 0.74 7.42 0.37 9.22e-13 Mean platelet volume; LIHC cis rs6570726 0.935 rs395948 chr6:145820185 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs4891159 0.660 rs4891160 chr18:74102135 C/T cg24786174 chr18:74118243 ZNF516 0.67 12.46 0.56 1.26e-29 Longevity; LIHC trans rs8030605 0.778 rs72740579 chr15:56640038 C/T cg01710580 chr16:598674 SOLH -0.66 -6.09 -0.31 3.08e-9 Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs950169 0.881 rs62029599 chr15:84956565 A/C cg17507749 chr15:85114479 UBE2QP1 0.73 8.5 0.42 5.84e-16 Schizophrenia; LIHC cis rs3096299 0.679 rs3096322 chr16:89441123 A/G cg08822215 chr16:89438651 ANKRD11 0.55 9.0 0.44 1.6e-17 Multiple myeloma (IgH translocation); LIHC cis rs28374715 0.609 rs8043237 chr15:41514298 G/A cg18705301 chr15:41695430 NDUFAF1 -0.88 -9.82 -0.47 3.36e-20 Ulcerative colitis; LIHC cis rs797680 0.856 rs4240966 chr1:93774812 C/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.67e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs2070488 0.662 rs7652475 chr3:38481341 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.58 8.13 0.4 7.92e-15 Electrocardiographic conduction measures; LIHC cis rs74417235 0.684 rs7723610 chr5:154053349 A/C cg08754654 chr5:154026448 NA 0.31 7.1 0.36 7.07e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs9309711 0.666 rs6723126 chr2:3484500 T/C cg04359351 chr2:3481828 TTC15 0.28 5.94 0.31 7.04e-9 Neurofibrillary tangles; LIHC cis rs1355223 1.000 rs1355223 chr11:34764479 A/G cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.38 -0.33 5.82e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs12980942 0.872 rs12327659 chr19:41796472 A/G cg25627403 chr19:41769009 HNRNPUL1 0.5 6.3 0.32 9.42e-10 Coronary artery disease; LIHC cis rs644799 1.000 rs586498 chr11:95537828 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.92 0.47 1.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9902453 0.817 rs880749 chr17:28059970 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.59 -0.53 2.02e-26 Coffee consumption (cups per day); LIHC cis rs9427116 0.875 rs11264233 chr1:154625632 C/T cg17218026 chr1:154582156 ADAR 0.31 6.07 0.31 3.3e-9 Blood protein levels; LIHC cis rs9790314 1.000 rs336570 chr3:161072054 A/G cg04691961 chr3:161091175 C3orf57 0.41 6.48 0.33 3.12e-10 Morning vs. evening chronotype; LIHC cis rs11955398 0.501 rs4235480 chr5:60032371 C/T cg02684056 chr5:59996105 DEPDC1B -0.4 -5.71 -0.3 2.46e-8 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.875 rs9403770 chr6:146423334 C/T cg23711669 chr6:146136114 FBXO30 0.64 10.83 0.51 1.07e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs9916302 0.904 rs7210488 chr17:37539819 T/G cg00129232 chr17:37814104 STARD3 0.39 6.27 0.32 1.11e-9 Glomerular filtration rate (creatinine); LIHC cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg00149659 chr3:10157352 C3orf10 0.67 7.04 0.36 1.04e-11 Alzheimer's disease; LIHC cis rs1034435 0.723 rs713946 chr22:48891376 T/C cg05992904 chr22:48892994 FAM19A5 -0.52 -10.65 -0.5 4.47e-23 Late-onset Alzheimer's disease; LIHC cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg13393036 chr8:95962371 TP53INP1 -0.43 -10.18 -0.48 2.02e-21 Type 2 diabetes; LIHC cis rs796364 0.806 rs74266489 chr2:201005732 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs17376456 0.542 rs1453003 chr5:93151611 T/C cg25358565 chr5:93447407 FAM172A -0.79 -7.68 -0.38 1.74e-13 Diabetic retinopathy; LIHC cis rs6088590 0.687 rs6088580 chr20:33285053 G/C cg08999081 chr20:33150536 PIGU 0.61 11.18 0.52 6.06e-25 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01500945 chr16:51185672 SALL1 0.45 6.8 0.35 4.72e-11 Lung function (FEV1/FVC); LIHC cis rs9649213 1.000 rs9649213 chr7:98021211 A/G cg09267113 chr7:98030324 BAIAP2L1 -0.49 -9.14 -0.44 5.81e-18 Prostate cancer (SNP x SNP interaction); LIHC cis rs4903214 0.895 rs10142706 chr14:74717304 A/G cg11132536 chr14:74711944 VSX2 -0.24 -5.96 -0.31 6.29e-9 Inflammatory bowel disease; LIHC cis rs10131894 0.611 rs174994 chr14:75434102 A/G cg08847533 chr14:75593920 NEK9 -0.82 -15.69 -0.65 3.74e-42 Coronary artery disease; LIHC cis rs4906332 1.000 rs3783398 chr14:103949378 C/T cg04998671 chr14:104000505 TRMT61A 0.46 6.28 0.32 1.05e-9 Coronary artery disease; LIHC cis rs7903847 0.642 rs1537646 chr10:99149922 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.58 -0.34 1.72e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9916302 0.851 rs12936646 chr17:37647450 A/T cg00129232 chr17:37814104 STARD3 -0.42 -6.81 -0.35 4.45e-11 Glomerular filtration rate (creatinine); LIHC cis rs1005277 0.563 rs2505215 chr10:38481273 A/G cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7772486 0.790 rs9376968 chr6:146180364 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.48 0.53 5.19e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs35883536 1.000 rs17403905 chr1:101107358 T/C cg14515779 chr1:101123966 NA -0.67 -13.22 -0.58 1.65e-32 Monocyte count; LIHC cis rs9399135 0.967 rs7741626 chr6:135314182 C/T cg22676075 chr6:135203613 NA 0.39 6.38 0.33 5.82e-10 Red blood cell count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24274347 chr12:132497611 EP400 -0.4 -6.1 -0.31 2.81e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg05564831 chr3:52568323 NT5DC2 0.37 5.93 0.31 7.25e-9 Bipolar disorder; LIHC cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg08888203 chr3:10149979 C3orf24 0.59 6.93 0.35 2.13e-11 Alzheimer's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01123250 chr2:210673545 UNC80 0.34 6.47 0.33 3.33e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7107174 1.000 rs57738705 chr11:77994489 A/G cg02023728 chr11:77925099 USP35 0.51 9.79 0.47 4.25e-20 Testicular germ cell tumor; LIHC cis rs6466055 0.720 rs1204056 chr7:104957761 G/A cg04380332 chr7:105027541 SRPK2 0.37 6.84 0.35 3.76e-11 Schizophrenia; LIHC cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.06 10.94 0.51 4.24e-24 Platelet count; LIHC cis rs372883 0.530 rs2832305 chr21:30752964 G/A cg24692254 chr21:30365293 RNF160 0.46 5.99 0.31 5.45e-9 Pancreatic cancer; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg18876405 chr7:65276391 NA 0.33 5.9 0.3 8.69e-9 Calcium levels; LIHC cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg20090690 chr10:134436459 INPP5A 0.44 5.77 0.3 1.76e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs34172651 0.517 rs1465423 chr16:24772680 C/G cg04756594 chr16:24857601 SLC5A11 -0.6 -9.12 -0.44 6.69e-18 Intelligence (multi-trait analysis); LIHC cis rs11105298 0.891 rs11105309 chr12:89909850 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.3 -0.37 1.97e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7153648 1.000 rs7153648 chr14:61122526 C/G cg27398547 chr14:60952738 C14orf39 0.63 7.05 0.36 1.02e-11 Prostate cancer; LIHC cis rs7309 0.810 rs11684253 chr2:162034536 G/T cg16506815 chr2:162101123 NA 0.57 9.86 0.47 2.46e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs2075371 0.501 rs1646652 chr7:134024515 A/T cg20476274 chr7:133979776 SLC35B4 0.42 5.8 0.3 1.5e-8 Mean platelet volume; LIHC trans rs2921073 0.605 rs2976933 chr8:8254875 A/G cg02759110 chr4:141489859 UCP1 -0.48 -6.37 -0.33 6.14e-10 Parkinson's disease; LIHC cis rs16944613 0.588 rs6496698 chr15:91135558 A/G cg26821196 chr15:91095069 CRTC3 0.43 7.27 0.37 2.5e-12 Colorectal cancer; LIHC cis rs11098499 0.954 rs59394118 chr4:120295551 A/G cg09307838 chr4:120376055 NA 0.76 11.49 0.53 4.66e-26 Corneal astigmatism; LIHC cis rs919433 1.000 rs7422899 chr2:198163527 G/C cg03934865 chr2:198174659 NA -0.59 -9.35 -0.45 1.19e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2806561 0.964 rs1757041 chr1:23506063 G/A cg19743168 chr1:23544995 NA 0.43 8.3 0.41 2.37e-15 Height; LIHC cis rs172166 0.769 rs149965 chr6:28018689 T/A cg16479474 chr6:28041457 NA 0.38 6.3 0.32 9.1e-10 Cardiac Troponin-T levels; LIHC cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg18404041 chr3:52824283 ITIH1 -0.58 -9.73 -0.47 6.39e-20 Electroencephalogram traits; LIHC cis rs57590327 0.503 rs13079104 chr3:81886039 A/T cg07356753 chr3:81810745 GBE1 -0.54 -8.25 -0.41 3.47e-15 Extraversion; LIHC cis rs7937682 0.961 rs7106104 chr11:111635655 T/C cg09085632 chr11:111637200 PPP2R1B 1.21 19.96 0.73 2.46e-59 Primary sclerosing cholangitis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02585790 chr2:232329254 NCL 0.56 7.12 0.36 6.35e-12 Lung function (FEV1/FVC); LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg22442454 chr1:209979470 IRF6 0.4 6.17 0.32 1.94e-9 Cleft lip with or without cleft palate; LIHC cis rs2559856 0.967 rs7970837 chr12:102081576 A/G cg12924262 chr12:102091054 CHPT1 0.5 7.95 0.4 2.7e-14 Blood protein levels; LIHC cis rs73001065 0.818 rs10500212 chr19:19723215 C/T cg03709012 chr19:19516395 GATAD2A 0.82 7.64 0.38 2.28e-13 LDL cholesterol; LIHC cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg06466757 chr4:1255808 NA -0.35 -5.9 -0.3 8.82e-9 Obesity-related traits; LIHC cis rs10861342 1.000 rs10861337 chr12:105452442 G/A cg23923672 chr12:105501055 KIAA1033 0.69 8.03 0.4 1.63e-14 IgG glycosylation; LIHC cis rs8017423 0.967 rs7154683 chr14:90700692 A/G cg14092571 chr14:90743983 NA -0.37 -5.8 -0.3 1.53e-8 Mortality in heart failure; LIHC cis rs34779708 0.966 rs11010122 chr10:35493518 A/C cg03585969 chr10:35415529 CREM 0.85 12.81 0.57 6.11e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2153535 0.580 rs9505457 chr6:8479142 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs1008375 0.931 rs3775926 chr4:17599837 G/A cg16339924 chr4:17578868 LAP3 0.46 6.32 0.32 8.07e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs798554 0.660 rs2527687 chr7:2838485 G/A cg13628971 chr7:2884303 GNA12 0.42 6.52 0.33 2.55e-10 Height; LIHC cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg10802521 chr3:52805072 NEK4 -0.37 -5.93 -0.31 7.28e-9 Bipolar disorder; LIHC cis rs6952808 0.792 rs4721184 chr7:1950784 T/C cg04267008 chr7:1944627 MAD1L1 -0.73 -11.8 -0.54 3.42e-27 Bipolar disorder and schizophrenia; LIHC cis rs7546668 1.000 rs12759296 chr1:15881237 T/G cg11706911 chr1:15910989 AGMAT 0.43 6.39 0.33 5.41e-10 Glomerular filtration rate (creatinine); LIHC cis rs17270561 1.000 rs12211184 chr6:25823774 G/A cg17691542 chr6:26056736 HIST1H1C 0.71 7.98 0.4 2.23e-14 Iron status biomarkers; LIHC cis rs2749592 0.550 rs7081464 chr10:37883937 C/T cg00409905 chr10:38381863 ZNF37A 0.51 8.54 0.42 4.38e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9790314 0.560 rs1450521 chr3:161091237 C/A cg03342759 chr3:160939853 NMD3 -0.43 -6.25 -0.32 1.21e-9 Morning vs. evening chronotype; LIHC cis rs798554 0.683 rs1182155 chr7:2902890 C/G cg13628971 chr7:2884303 GNA12 0.55 8.84 0.43 5.19e-17 Height; LIHC cis rs7027203 0.828 rs4744287 chr9:96585567 A/G cg14598338 chr9:96623480 NA 0.32 6.46 0.33 3.59e-10 DNA methylation (variation); LIHC cis rs9911578 0.967 rs7214892 chr17:57065401 G/A cg12560992 chr17:57184187 TRIM37 0.99 17.64 0.69 5.54e-50 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.500 rs1843736 chr12:34012080 C/G cg26384229 chr12:38710491 ALG10B 0.52 7.3 0.37 2.05e-12 Morning vs. evening chronotype; LIHC cis rs6088813 1.000 rs6088825 chr20:33995972 C/T cg14752227 chr20:34000481 UQCC -0.41 -5.88 -0.3 9.69e-9 Height; LIHC cis rs17102423 0.685 rs7156617 chr14:65541381 G/A cg11161011 chr14:65562177 MAX -0.46 -6.7 -0.34 8.55e-11 Obesity-related traits; LIHC cis rs6061231 1.000 rs13043313 chr20:60958269 A/G cg06026331 chr20:60912101 LAMA5 0.4 5.96 0.31 6.23e-9 Colorectal cancer; LIHC cis rs936229 0.861 rs12441505 chr15:75107311 A/C cg14664628 chr15:75095509 CSK -1.04 -22.1 -0.77 7.08e-68 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs2153535 0.580 rs9378556 chr6:8514695 A/G cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.26e-27 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23115158 chr6:80341412 SH3BGRL2 0.46 6.12 0.31 2.58e-9 Lung function (FEV1/FVC); LIHC trans rs11098499 0.780 rs7680914 chr4:120563053 A/G cg25214090 chr10:38739885 LOC399744 0.56 8.86 0.43 4.48e-17 Corneal astigmatism; LIHC trans rs7618501 0.501 rs7627864 chr3:49926613 C/G cg21659725 chr3:3221576 CRBN 0.57 8.19 0.4 5.34e-15 Intelligence (multi-trait analysis); LIHC cis rs8072100 0.875 rs4794047 chr17:45763005 A/T cg19378624 chr17:45501242 LOC100272146;C17orf57 0.4 6.36 0.33 6.29e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6960043 0.818 rs1974619 chr7:15065300 C/T cg19272540 chr7:15055459 NA -0.24 -6.74 -0.34 6.6e-11 Type 2 diabetes; LIHC cis rs6450176 0.909 rs3776720 chr5:53296158 A/G ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.51 -0.62 1.72e-37 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs12477438 0.520 rs11689265 chr2:99799267 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 14.26 0.61 1.52e-36 Chronic sinus infection; LIHC cis rs9916302 0.904 rs10491128 chr17:37551988 G/A cg07936489 chr17:37558343 FBXL20 0.82 13.01 0.58 1e-31 Glomerular filtration rate (creatinine); LIHC trans rs4650994 1.000 rs6660445 chr1:178528871 C/T cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 6.27e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs12579753 0.917 rs71466033 chr12:82242187 C/T cg07988820 chr12:82153109 PPFIA2 -0.47 -5.78 -0.3 1.69e-8 Resting heart rate; LIHC cis rs5769765 0.773 rs9616382 chr22:50312979 C/T cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs7582180 0.629 rs12620139 chr2:100943446 A/G cg14675211 chr2:100938903 LONRF2 0.56 8.72 0.43 1.27e-16 Intelligence (multi-trait analysis); LIHC cis rs7301016 0.846 rs11174571 chr12:63022329 C/T cg11441379 chr12:63026424 NA 0.6 6.15 0.32 2.12e-9 IgG glycosylation; LIHC cis rs3770081 1.000 rs60649958 chr2:86283000 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -8.69 -0.43 1.57e-16 Facial emotion recognition (sad faces); LIHC cis rs2549003 1.000 rs2070728 chr5:131819977 C/T cg02551604 chr5:131831745 NA -0.44 -6.54 -0.33 2.24e-10 Asthma (sex interaction); LIHC cis rs79057730 0.599 rs79272827 chr7:807015 C/G cg06242242 chr7:766104 PRKAR1B;HEATR2 0.82 9.15 0.44 5.21e-18 Initial pursuit acceleration; LIHC cis rs2518564 0.507 rs866484 chr1:158986477 C/G cg11003133 chr1:159046391 AIM2 0.26 5.8 0.3 1.52e-8 White blood cell count; LIHC cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.99 8.71 0.43 1.35e-16 Platelet count; LIHC cis rs3806843 1.000 rs12055222 chr5:140165568 T/C cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7131987 0.903 rs10843371 chr12:29414232 G/A cg21486233 chr12:29375141 FAR2 0.3 5.82 0.3 1.36e-8 QT interval; LIHC cis rs2153535 0.580 rs1932279 chr6:8473653 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs7959452 0.719 rs57954211 chr12:69748397 C/A cg20891283 chr12:69753455 YEATS4 0.9 18.61 0.71 7.12e-54 Blood protein levels; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg09367891 chr1:107599246 PRMT6 0.69 11.35 0.52 1.45e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6547741 0.788 rs7595739 chr2:27874563 G/T cg27432699 chr2:27873401 GPN1 -0.85 -14.65 -0.62 4.54e-38 Oral cavity cancer; LIHC cis rs950169 0.519 rs7237 chr15:85186577 C/T cg12863693 chr15:85201151 NMB 0.46 6.66 0.34 1.11e-10 Schizophrenia; LIHC cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg08822215 chr16:89438651 ANKRD11 -0.43 -6.75 -0.34 6.28e-11 Multiple myeloma (IgH translocation); LIHC cis rs1008375 0.932 rs7677212 chr4:17675932 A/G cg16339924 chr4:17578868 LAP3 -0.46 -6.17 -0.32 1.88e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7000551 0.663 rs7827093 chr8:22334610 A/G cg12081754 chr8:22256438 SLC39A14 0.44 7.24 0.36 2.98e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7020830 0.867 rs7852593 chr9:37332380 A/T cg14294708 chr9:37120828 ZCCHC7 1.14 24.31 0.8 1.58e-76 Schizophrenia; LIHC cis rs9768139 0.658 rs896778 chr7:158113270 A/G cg25566285 chr7:158114605 PTPRN2 0.23 6.15 0.32 2.14e-9 Calcium levels; LIHC cis rs9916302 0.904 rs55689507 chr17:37404436 G/C cg07936489 chr17:37558343 FBXL20 -0.8 -12.84 -0.57 4.63e-31 Glomerular filtration rate (creatinine); LIHC cis rs4625783 0.583 rs11077974 chr17:80095193 A/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.59e-9 Blood metabolite levels; LIHC cis rs17376456 0.825 rs66564678 chr5:93165894 C/T cg25358565 chr5:93447407 FAM172A 1.05 9.44 0.45 6.16e-19 Diabetic retinopathy; LIHC cis rs6693567 0.874 rs698915 chr1:150388318 C/T cg15654264 chr1:150340011 RPRD2 -0.42 -6.17 -0.32 1.96e-9 Migraine; LIHC cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg13607699 chr17:42295918 UBTF -0.44 -7.13 -0.36 5.89e-12 Total body bone mineral density; LIHC cis rs9368481 0.672 rs3931463 chr6:26939797 G/A cg18867708 chr6:26865862 GUSBL1 0.54 8.2 0.41 4.83e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs11098499 0.955 rs7684942 chr4:120162201 C/T cg09307838 chr4:120376055 NA 0.75 11.05 0.51 1.83e-24 Corneal astigmatism; LIHC cis rs4819052 0.634 rs8128636 chr21:46690633 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 10.26 0.49 1.06e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7582180 0.614 rs1530031 chr2:101009326 T/C cg14675211 chr2:100938903 LONRF2 0.58 8.48 0.42 6.77e-16 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.500 rs11053189 chr12:34433455 G/A cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs11711311 1.000 rs2242108 chr3:113433903 T/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.41 0.45 7.27e-19 IgG glycosylation; LIHC cis rs7208859 0.623 rs9912283 chr17:29110373 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs61041384 0.661 rs74240781 chr12:123792701 T/C cg07919128 chr17:18022025 MYO15A 0.75 7.54 0.38 4.13e-13 Schizophrenia; LIHC cis rs10504229 0.906 rs28447218 chr8:58170813 T/G cg21724239 chr8:58056113 NA 0.46 6.06 0.31 3.55e-9 Developmental language disorder (linguistic errors); LIHC cis rs2933343 0.700 rs789238 chr3:128636715 A/G cg25356066 chr3:128598488 ACAD9 0.53 7.47 0.37 6.95e-13 IgG glycosylation; LIHC trans rs459571 0.804 rs448918 chr9:136885979 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.6 -9.36 -0.45 1.07e-18 Platelet distribution width; LIHC cis rs950169 0.881 rs4081123 chr15:84956235 A/G cg17507749 chr15:85114479 UBE2QP1 0.73 8.5 0.42 5.84e-16 Schizophrenia; LIHC cis rs548181 0.611 rs1293672 chr11:125461034 A/G cg03464685 chr11:125439445 EI24 1.39 14.54 0.62 1.26e-37 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7582720 0.943 rs72932559 chr2:203847382 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs904251 0.772 rs10692 chr6:37450914 T/C cg01843034 chr6:37503916 NA -0.4 -6.54 -0.33 2.22e-10 Cognitive performance; LIHC cis rs7937890 0.587 rs11023204 chr11:14411223 C/A cg02251663 chr11:14281053 SPON1 -0.43 -5.79 -0.3 1.57e-8 Mitochondrial DNA levels; LIHC cis rs240764 0.658 rs60658003 chr6:101201191 C/A cg09795085 chr6:101329169 ASCC3 -0.47 -6.93 -0.35 2.14e-11 Neuroticism; LIHC cis rs72781680 0.898 rs12623079 chr2:24103749 G/A cg08917208 chr2:24149416 ATAD2B 0.87 8.2 0.41 4.78e-15 Lymphocyte counts; LIHC cis rs1055129 0.655 rs8067076 chr17:73837142 G/T cg08125733 chr17:73851984 WBP2 -0.51 -8.33 -0.41 1.92e-15 White matter hyperintensity burden; LIHC cis rs7572733 0.534 rs700681 chr2:198711502 C/A cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg05590025 chr7:65112418 INTS4L2 0.53 6.24 0.32 1.3e-9 Diabetic kidney disease; LIHC cis rs6545883 0.929 rs2593627 chr2:61618574 T/C cg15711740 chr2:61764176 XPO1 0.42 5.85 0.3 1.13e-8 Tuberculosis; LIHC cis rs6502050 0.871 rs6502056 chr17:80070912 C/G cg11859384 chr17:80120422 CCDC57 0.43 5.89 0.3 9.07e-9 Life satisfaction; LIHC cis rs7617773 0.780 rs13090538 chr3:48370769 A/C cg11946769 chr3:48343235 NME6 0.93 11.99 0.54 6.8e-28 Coronary artery disease; LIHC cis rs7700895 0.737 rs3777184 chr5:95262044 G/C cg10483112 chr5:95245456 ELL2 -0.38 -6.9 -0.35 2.59e-11 IgG glycosylation; LIHC cis rs1982963 0.950 rs61973203 chr14:52510567 A/G cg10843707 chr14:52510701 NID2 0.46 8.36 0.41 1.55e-15 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs67311347 1.000 rs9829800 chr3:40443927 T/C cg18306943 chr3:40428807 ENTPD3 0.33 5.72 0.3 2.29e-8 Renal cell carcinoma; LIHC cis rs9733 0.744 rs12568757 chr1:150729793 C/T cg18016565 chr1:150552671 MCL1 -0.51 -9.99 -0.48 8.84e-21 Tonsillectomy; LIHC trans rs7714584 1.000 rs11167520 chr5:150265639 T/C cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC trans rs916888 0.610 rs199529 chr17:44837217 A/C cg12297030 chr17:43662878 NA -0.63 -6.23 -0.32 1.38e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs5769765 0.908 rs9616376 chr22:50310829 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.85 -10.37 -0.49 4.36e-22 Schizophrenia; LIHC cis rs7927592 0.830 rs7120635 chr11:68261293 A/G cg16797656 chr11:68205561 LRP5 0.55 9.05 0.44 1.08e-17 Total body bone mineral density; LIHC cis rs847649 0.731 rs1829957 chr7:102687010 T/A cg18108683 chr7:102477205 FBXL13 0.4 6.08 0.31 3.26e-9 Morning vs. evening chronotype; LIHC cis rs4555082 0.834 rs2735819 chr14:105713449 C/T cg06808227 chr14:105710500 BRF1 -0.5 -6.14 -0.32 2.23e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg00750074 chr16:89608354 SPG7 -0.51 -8.18 -0.4 5.81e-15 Multiple myeloma (IgH translocation); LIHC cis rs875971 0.825 rs10281499 chr7:66048966 A/G cg18876405 chr7:65276391 NA -0.34 -6.29 -0.32 9.45e-10 Aortic root size; LIHC cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg06634786 chr22:41940651 POLR3H -0.76 -8.37 -0.41 1.53e-15 Vitiligo; LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg08280861 chr8:58055591 NA 0.54 5.87 0.3 1.05e-8 Developmental language disorder (linguistic errors); LIHC cis rs2839186 1.000 rs2839186 chr21:47690068 C/T cg13126279 chr21:47581558 C21orf56 -0.42 -6.52 -0.33 2.57e-10 Testicular germ cell tumor; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg05368115 chr19:901123 C19orf22 0.45 6.22 0.32 1.44e-9 Bilirubin levels; LIHC trans rs1005277 0.540 rs7903942 chr10:37929276 C/T cg27523141 chr10:43048294 ZNF37B -0.39 -6.79 -0.34 5.12e-11 Extrinsic epigenetic age acceleration; LIHC trans rs2727020 0.658 rs4980431 chr11:49350071 G/T cg15704280 chr7:45808275 SEPT13 -0.93 -17.51 -0.69 1.81e-49 Coronary artery disease; LIHC cis rs6088580 0.524 rs6088565 chr20:33254986 A/C cg08999081 chr20:33150536 PIGU -0.43 -7.18 -0.36 4.49e-12 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13441983 chr11:10327014 ADM 0.44 6.74 0.34 6.77e-11 Pancreatic cancer; LIHC cis rs2841277 0.676 rs4264326 chr14:105411700 A/G cg21017887 chr14:105400489 NA 0.67 12.5 0.56 8.74e-30 Rheumatoid arthritis; LIHC cis rs12478296 0.591 rs12468297 chr2:242996474 A/G cg06360820 chr2:242988706 NA -0.73 -11.86 -0.54 2e-27 Obesity-related traits; LIHC cis rs13064411 0.696 rs6438156 chr3:113206929 C/A cg18753928 chr3:113234510 CCDC52 -0.42 -6.04 -0.31 4.11e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs8077889 0.917 rs9894873 chr17:41911832 A/G cg26893861 chr17:41843967 DUSP3 0.91 10.34 0.49 5.39e-22 Triglycerides; LIHC cis rs597539 0.652 rs674654 chr11:68698762 G/T cg04772025 chr11:68637568 NA 0.49 6.35 0.32 6.96e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7945718 0.806 rs11022507 chr11:12829753 A/T cg25843174 chr11:12811716 TEAD1 0.37 8.52 0.42 5.09e-16 Educational attainment (years of education); LIHC cis rs2455799 0.613 rs2470547 chr3:15737610 T/C cg12698662 chr3:15914712 MIR563 -0.36 -6.57 -0.33 1.87e-10 Mean platelet volume; LIHC trans rs1814175 0.645 rs847627 chr11:49927177 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs7432375 0.901 rs7618518 chr3:136370092 C/T cg21827317 chr3:136751795 NA -0.44 -5.85 -0.3 1.14e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg06238570 chr21:40685208 BRWD1 -0.4 -6.45 -0.33 3.71e-10 Menarche (age at onset); LIHC cis rs9287719 0.674 rs759399 chr2:10796883 T/C cg02829992 chr2:10710499 NA 0.38 5.95 0.31 6.59e-9 Prostate cancer; LIHC cis rs2075165 0.901 rs7522860 chr1:156275281 C/T cg06497051 chr1:156261200 TMEM79 0.34 5.9 0.3 8.84e-9 Tonsillectomy; LIHC cis rs6446731 0.517 rs2157093 chr4:3270913 C/G cg06533319 chr4:3265114 C4orf44 0.31 5.72 0.3 2.27e-8 Mean platelet volume; LIHC cis rs2153535 0.580 rs6927589 chr6:8456632 A/G cg23788917 chr6:8435910 SLC35B3 -0.6 -8.58 -0.42 3.33e-16 Motion sickness; LIHC cis rs7224685 0.906 rs2304586 chr17:4098998 A/G cg11204139 chr17:3907470 NA 0.63 8.26 0.41 3.19e-15 Type 2 diabetes; LIHC cis rs9303401 0.538 rs12603174 chr17:56489279 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.79 10.25 0.48 1.15e-21 Cognitive test performance; LIHC cis rs11711311 1.000 rs9830975 chr3:113486019 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.89 -0.35 2.65e-11 IgG glycosylation; LIHC cis rs208520 0.661 rs851466 chr6:66840476 A/G cg07460842 chr6:66804631 NA -0.8 -8.66 -0.42 1.95e-16 Exhaled nitric oxide output; LIHC cis rs1046896 0.561 rs8076476 chr17:80861017 A/C cg22027946 chr17:80790580 TBCD;ZNF750 0.52 7.63 0.38 2.37e-13 Glycated hemoglobin levels; LIHC cis rs7582180 0.739 rs4851292 chr2:100924761 A/G cg14675211 chr2:100938903 LONRF2 0.51 8.05 0.4 1.42e-14 Intelligence (multi-trait analysis); LIHC cis rs3741151 1.000 rs7129663 chr11:73045129 C/T cg17517138 chr11:73019481 ARHGEF17 0.95 6.93 0.35 2.12e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs10744422 0.920 rs10773657 chr12:123327900 C/A cg22842854 chr12:123319900 HIP1R -0.67 -8.73 -0.43 1.18e-16 Schizophrenia; LIHC cis rs7618501 1.000 rs2271960 chr3:49878078 A/G cg24110177 chr3:50126178 RBM5 -0.42 -6.66 -0.34 1.06e-10 Intelligence (multi-trait analysis); LIHC cis rs6835098 1.000 rs9990666 chr4:174083150 G/T cg27433088 chr4:174089019 GALNT7 0.38 6.93 0.35 2.07e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg26338869 chr17:61819248 STRADA 0.6 8.81 0.43 6.54e-17 Prudent dietary pattern; LIHC cis rs921968 0.541 rs620596 chr2:219462419 G/A cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.37e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs875971 0.862 rs7809814 chr7:65615397 G/A cg11764359 chr7:65958608 NA -0.83 -13.94 -0.6 2.66e-35 Aortic root size; LIHC cis rs13161895 1.000 rs6873781 chr5:179436734 A/C cg02702477 chr5:179499311 RNF130 -0.75 -10.29 -0.49 7.91e-22 LDL cholesterol; LIHC cis rs2901460 0.509 rs6721488 chr2:62071562 A/T cg02183531 chr2:62113199 CCT4 -0.42 -6.2 -0.32 1.61e-9 Mean corpuscular volume; LIHC cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg11890956 chr21:40555474 PSMG1 -0.54 -8.81 -0.43 6.31e-17 Cognitive function; LIHC cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -13.94 -0.6 2.78e-35 Alzheimer's disease; LIHC cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC trans rs6489882 0.703 rs1131476 chr12:113357209 G/A cg10175203 chr3:128143634 NA 0.39 6.33 0.32 7.64e-10 Chronic lymphocytic leukemia; LIHC cis rs9309473 0.632 rs11885217 chr2:73553208 A/G cg20560298 chr2:73613845 ALMS1 -0.41 -6.34 -0.32 7.48e-10 Metabolite levels; LIHC cis rs910316 0.967 rs175479 chr14:75561871 A/C cg11812906 chr14:75593930 NEK9 -0.78 -15.56 -0.64 1.18e-41 Height; LIHC cis rs6502050 0.835 rs34867501 chr17:80121358 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs12286929 0.610 rs11606838 chr11:115042859 C/A cg04055981 chr11:115044050 NA 0.39 6.66 0.34 1.13e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11608355 0.515 rs6606727 chr12:109941450 T/A cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs10504073 0.647 rs12549138 chr8:50007203 C/T cg00325661 chr8:49890786 NA 0.32 7.18 0.36 4.41e-12 Blood metabolite ratios; LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.520 rs34766932 chr2:99737273 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 13.19 0.58 2.05e-32 Chronic sinus infection; LIHC cis rs903552 0.800 rs8026048 chr15:102006353 G/A cg19295451 chr15:102010161 PCSK6 -0.5 -6.94 -0.35 1.94e-11 Diabetic kidney disease; LIHC cis rs40363 0.645 rs250633 chr16:3523002 C/T cg05754148 chr16:3507555 NAT15 0.39 6.49 0.33 3.02e-10 Tuberculosis; LIHC cis rs4665809 1.000 rs6704930 chr2:26325705 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.72 -0.43 1.26e-16 Gut microbiome composition (summer); LIHC cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.49e-11 Diabetic kidney disease; LIHC cis rs950169 0.887 rs12903946 chr15:84954430 T/C cg17507749 chr15:85114479 UBE2QP1 0.73 8.5 0.42 5.84e-16 Schizophrenia; LIHC cis rs611744 0.967 rs594405 chr8:109193607 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs5769765 0.955 rs9616204 chr22:50303530 T/C cg26441486 chr22:50317300 CRELD2 0.36 5.84 0.3 1.22e-8 Schizophrenia; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg13012494 chr21:47604986 C21orf56 0.39 5.9 0.3 8.83e-9 Testicular germ cell tumor; LIHC cis rs853679 0.517 rs1340004 chr6:28103691 C/T cg16479474 chr6:28041457 NA 0.43 6.07 0.31 3.36e-9 Depression; LIHC cis rs7618501 0.633 rs12485600 chr3:50025530 A/G cg21467203 chr3:49911342 NA -0.44 -7.79 -0.39 7.94e-14 Intelligence (multi-trait analysis); LIHC cis rs600806 0.850 rs4970846 chr1:109946095 A/C cg23091122 chr1:110024289 SYPL2 -0.44 -5.88 -0.3 9.61e-9 Intelligence (multi-trait analysis); LIHC cis rs12893668 0.703 rs34896432 chr14:104027995 C/T cg19000871 chr14:103996768 TRMT61A -0.44 -7.32 -0.37 1.83e-12 Reticulocyte count; LIHC cis rs10170846 0.800 rs10180462 chr2:223526385 C/T cg25565276 chr2:223520875 FARSB 0.63 9.32 0.45 1.52e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs7843479 0.965 rs1484162 chr8:21831385 A/G cg17168535 chr8:21777572 XPO7 0.42 6.68 0.34 9.99e-11 Mean corpuscular volume; LIHC cis rs9814567 0.929 rs13316205 chr3:134223563 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.45e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8103278 1.000 rs8102876 chr19:46332842 C/T cg02376097 chr19:46275166 DMPK -0.46 -6.97 -0.35 1.68e-11 Coronary artery disease; LIHC cis rs36051895 0.632 rs10815166 chr9:5149920 T/G cg02405213 chr9:5042618 JAK2 -0.68 -12.22 -0.55 9.28e-29 Pediatric autoimmune diseases; LIHC cis rs55823223 0.564 rs58363746 chr17:73850819 C/T cg10935138 chr17:73851978 WBP2 0.66 8.83 0.43 5.48e-17 Psoriasis; LIHC cis rs9309711 0.922 rs13431788 chr2:3482912 G/A cg10845886 chr2:3471009 TTC15 -0.62 -11.7 -0.53 8.08e-27 Neurofibrillary tangles; LIHC cis rs1048238 0.506 rs6668183 chr1:16173814 G/C cg00529422 chr1:16285251 ZBTB17 -0.34 -6.56 -0.33 1.94e-10 Systolic blood pressure; LIHC cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg15691649 chr6:25882328 NA -0.55 -7.93 -0.39 3.14e-14 Blood metabolite levels; LIHC trans rs12125971 1.000 rs11185012 chr1:107461522 T/A cg08941669 chr1:7778234 CAMTA1 0.57 6.09 0.31 3e-9 Intelligence; LIHC cis rs35306767 0.761 rs12770173 chr10:1027108 A/C cg20503657 chr10:835505 NA 0.84 7.51 0.38 5.07e-13 Eosinophil percentage of granulocytes; LIHC trans rs116095464 0.558 rs10055405 chr5:265666 C/T cg00938859 chr5:1591904 SDHAP3 0.58 7.05 0.36 1.03e-11 Breast cancer; LIHC cis rs4808199 0.948 rs7259434 chr19:19428805 A/T cg03709012 chr19:19516395 GATAD2A 0.99 15.93 0.65 4.11e-43 Nonalcoholic fatty liver disease; LIHC cis rs2273156 1.000 rs2273158 chr14:35465784 A/T cg16230307 chr14:35515116 FAM177A1 0.42 6.23 0.32 1.35e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC trans rs8073060 0.586 rs7213804 chr17:34010931 T/G cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7116495 1.000 rs6592455 chr11:71689541 C/T cg26138937 chr11:71823887 C11orf51 0.88 8.83 0.43 5.49e-17 Severe influenza A (H1N1) infection; LIHC trans rs7246657 0.891 rs7257495 chr19:37823876 C/G cg24637308 chr11:6592297 DNHD1 0.44 6.17 0.32 1.98e-9 Coronary artery calcification; LIHC cis rs539096 0.566 rs3011220 chr1:44308867 A/G cg12908607 chr1:44402522 ARTN -0.46 -7.93 -0.39 3.1e-14 Intelligence (multi-trait analysis); LIHC cis rs3204270 0.639 rs62077183 chr17:79658940 C/A cg18367735 chr17:79674897 NA 0.7 8.33 0.41 2.04e-15 Dental caries; LIHC trans rs35110281 0.811 rs9980185 chr21:45057905 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.37 0.33 6.18e-10 Mean corpuscular volume; LIHC cis rs60871478 0.838 rs7789321 chr7:800977 A/G cg27478167 chr7:817139 HEATR2 -0.52 -6.94 -0.35 1.93e-11 Cerebrospinal P-tau181p levels; LIHC cis rs4906332 0.782 rs7161305 chr14:104002234 G/A cg04998671 chr14:104000505 TRMT61A -0.57 -7.14 -0.36 5.48e-12 Coronary artery disease; LIHC cis rs116248771 0.739 rs2082158 chr3:158359791 G/C cg16708174 chr3:158430962 RARRES1 0.48 6.42 0.33 4.46e-10 diarrhoeal disease at age 2; LIHC cis rs7098414 0.511 rs7898787 chr10:82156042 G/A cg00277334 chr10:82204260 NA -0.61 -9.99 -0.48 8.77e-21 Post bronchodilator FEV1; LIHC cis rs9611565 0.512 rs132767 chr22:42009520 C/T cg06634786 chr22:41940651 POLR3H -0.57 -5.95 -0.31 6.72e-9 Vitiligo; LIHC cis rs6061231 0.834 rs2427307 chr20:60966686 G/A cg24112000 chr20:60950667 NA -0.59 -8.59 -0.42 3.03e-16 Colorectal cancer; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg12311636 chr6:118886798 C6orf204 -0.53 -6.22 -0.32 1.44e-9 Diastolic blood pressure; LIHC cis rs16828019 0.777 rs2300658 chr1:41505022 G/A cg03387723 chr1:41708464 SCMH1 -0.41 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.967 rs377753 chr6:167389496 A/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs7089973 0.604 rs7897937 chr10:116591318 A/G cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2439831 1.000 rs7173487 chr15:43750239 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.73 10.93 0.51 4.75e-24 Lung cancer in ever smokers; LIHC cis rs12451471 0.559 rs34746710 chr17:78079224 G/A cg24585782 chr17:78113791 EIF4A3 -0.42 -5.75 -0.3 1.99e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg05025164 chr4:1340916 KIAA1530 -0.72 -10.34 -0.49 5.67e-22 Longevity; LIHC cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg27170947 chr2:26402098 FAM59B -0.72 -8.67 -0.42 1.7e-16 Gut microbiome composition (summer); LIHC cis rs3741151 1.000 rs78433080 chr11:73067565 G/A cg17517138 chr11:73019481 ARHGEF17 0.93 6.79 0.34 4.98e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs35110281 0.712 rs167930 chr21:44946625 G/A cg21573476 chr21:45109991 RRP1B -0.51 -9.54 -0.46 2.8e-19 Mean corpuscular volume; LIHC cis rs4919087 0.810 rs10786321 chr10:99026112 T/C cg25902810 chr10:99078978 FRAT1 0.65 9.51 0.46 3.56e-19 Monocyte count; LIHC cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.03 9.63 0.46 1.4e-19 Platelet count; LIHC cis rs8067545 0.611 rs2526482 chr17:20119133 C/T cg13482628 chr17:19912719 NA -0.42 -6.94 -0.35 1.98e-11 Schizophrenia; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg02464098 chr8:26240309 BNIP3L -0.54 -6.18 -0.32 1.87e-9 Preeclampsia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03972606 chr2:234750062 HJURP 0.45 6.22 0.32 1.46e-9 Lung function (FEV1/FVC); LIHC cis rs10464366 0.746 rs62442210 chr7:39146328 G/T cg15212455 chr7:39170539 POU6F2 0.46 8.02 0.4 1.72e-14 IgG glycosylation; LIHC cis rs9649465 1.000 rs12537287 chr7:123364747 G/A cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.15e-15 Migraine; LIHC cis rs208520 0.802 rs208496 chr6:66930786 G/C cg07460842 chr6:66804631 NA -0.76 -8.38 -0.41 1.42e-15 Exhaled nitric oxide output; LIHC cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg18252515 chr7:66147081 NA -1.29 -16.5 -0.67 2e-45 Diabetic kidney disease; LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg00800038 chr16:89945340 TCF25 -0.66 -10.56 -0.5 9.36e-23 Skin colour saturation; LIHC cis rs2153535 0.580 rs4365970 chr6:8453813 C/T cg07606381 chr6:8435919 SLC35B3 -0.79 -11.81 -0.54 3.22e-27 Motion sickness; LIHC cis rs11190604 0.945 rs2495746 chr10:102328270 T/C cg07080220 chr10:102295463 HIF1AN 0.51 7.09 0.36 7.56e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3106136 0.527 rs4235050 chr4:95157156 A/G cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.02 -0.44 1.33e-17 Capecitabine sensitivity; LIHC cis rs2120019 0.567 rs28844983 chr15:75178088 T/A cg09165964 chr15:75287851 SCAMP5 -0.48 -6.38 -0.33 5.84e-10 Blood trace element (Zn levels); LIHC cis rs10876993 0.928 rs1689596 chr12:58053029 T/C cg18357645 chr12:58087776 OS9 0.51 8.46 0.42 7.66e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs72781680 1.000 rs12620594 chr2:24194490 G/A cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs208520 0.690 rs1885100 chr6:66871047 C/G cg07460842 chr6:66804631 NA -0.78 -8.65 -0.42 1.99e-16 Exhaled nitric oxide output; LIHC cis rs6540556 0.723 rs1000282 chr1:209894785 T/C cg05527609 chr1:210001259 C1orf107 -0.56 -7.72 -0.39 1.29e-13 Red blood cell count; LIHC cis rs2274273 0.840 rs6573013 chr14:55735873 A/C cg01864836 chr14:55583639 NA -0.38 -7.02 -0.35 1.22e-11 Protein biomarker; LIHC cis rs3741404 0.791 rs7112960 chr11:63907079 A/G cg18225595 chr11:63971243 STIP1 0.68 10.77 0.5 1.77e-23 Platelet count; LIHC cis rs3806843 0.868 rs2563281 chr5:140131219 T/A cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2066819 1.000 rs1274493 chr12:56682371 C/T cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Psoriasis vulgaris; LIHC cis rs12291225 0.585 rs12270374 chr11:14375079 T/C cg19336497 chr11:14380999 RRAS2 -0.67 -14.11 -0.61 5.91e-36 Sense of smell; LIHC cis rs1580019 0.961 rs958217 chr7:32493417 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.65 0.53 1.18e-26 Cognitive ability; LIHC cis rs7131987 0.718 rs7976961 chr12:29463088 C/T cg05697976 chr12:29376483 FAR2 0.3 6.04 0.31 4.07e-9 QT interval; LIHC cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs2346177 0.844 rs4953365 chr2:46644946 G/C cg02822958 chr2:46747628 ATP6V1E2 0.4 6.06 0.31 3.63e-9 HDL cholesterol; LIHC cis rs7620457 1.000 rs7620457 chr3:183747266 A/G cg01324343 chr3:183735012 ABCC5 -0.71 -7.51 -0.38 5.15e-13 Body mass index; LIHC cis rs4930561 0.714 rs7126326 chr11:67947275 T/G cg04465784 chr11:67976953 SUV420H1 -0.3 -5.76 -0.3 1.87e-8 Breast cancer in childhood cancer survivors;IgG glycosylation; LIHC cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.97 -11.94 -0.54 1.03e-27 Alzheimer's disease; LIHC cis rs2073300 1.000 rs2207989 chr20:23446014 T/G cg12062639 chr20:23401060 NAPB 0.83 9.78 0.47 4.3e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7208859 0.623 rs11650271 chr17:29213943 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs801193 1.000 rs6958520 chr7:66151453 T/C cg26939375 chr7:64535504 NA 0.43 6.84 0.35 3.64e-11 Aortic root size; LIHC cis rs2108225 0.837 rs7810937 chr7:107447500 A/G cg18560240 chr7:107437656 SLC26A3 -0.45 -6.87 -0.35 3.11e-11 Ulcerative colitis; LIHC cis rs6448317 1.000 rs11938296 chr4:24938861 A/G cg21108841 chr4:24914750 CCDC149 -0.47 -6.0 -0.31 5e-9 Heschl's gyrus morphology; LIHC trans rs208520 0.661 rs7766144 chr6:66827795 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -8.08 -0.4 1.12e-14 Exhaled nitric oxide output; LIHC cis rs4561483 0.603 rs7202065 chr16:11951045 C/T cg08843971 chr16:11963173 GSPT1 0.37 6.74 0.34 6.6e-11 Testicular germ cell tumor; LIHC cis rs72781680 0.678 rs2551341 chr2:24014778 G/T cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.07e-9 Lymphocyte counts; LIHC cis rs16828019 0.929 rs12029321 chr1:41682530 G/C cg20697417 chr1:41786797 NA 0.34 6.51 0.33 2.61e-10 Intelligence (multi-trait analysis); LIHC cis rs4803455 0.565 rs1025497 chr19:41871254 A/G cg09537434 chr19:41945824 ATP5SL -0.72 -10.99 -0.51 2.92e-24 Migraine;Coronary artery disease; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg03874509 chr1:107600012 PRMT6 0.69 10.03 0.48 6.39e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9715521 0.677 rs67500083 chr4:59862419 C/T cg11281224 chr4:60001000 NA -0.34 -6.35 -0.32 6.75e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7959452 0.570 rs10878964 chr12:69720691 T/G cg14784868 chr12:69753453 YEATS4 0.88 16.86 0.67 7.47e-47 Blood protein levels; LIHC cis rs12887734 0.546 rs12885509 chr14:104273325 T/C cg01849466 chr14:104193079 ZFYVE21 -0.39 -5.87 -0.3 1.02e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs5753037 0.629 rs140138 chr22:30164628 T/G cg01021169 chr22:30184971 ASCC2 -0.32 -5.84 -0.3 1.24e-8 Type 1 diabetes; LIHC cis rs11945232 1.000 rs11945232 chr4:88342369 A/G cg23841344 chr4:88312519 HSD17B11 -0.57 -7.72 -0.39 1.29e-13 Intelligence (multi-trait analysis); LIHC cis rs9359856 0.564 rs72913976 chr6:90390233 T/C cg13799429 chr6:90582589 CASP8AP2 -0.67 -6.39 -0.33 5.41e-10 Bipolar disorder; LIHC cis rs9640161 0.789 rs3735174 chr7:150020489 T/C cg17279839 chr7:150038598 RARRES2 0.5 10.58 0.5 7.8e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs1018836 0.923 rs9643298 chr8:91552502 G/A cg16814680 chr8:91681699 NA -0.66 -10.84 -0.51 9.9899999999999993e-24 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1577917 1.000 rs12213740 chr6:86656733 A/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.93 -0.35 2.09e-11 Response to antipsychotic treatment; LIHC cis rs1577917 1.000 rs1962716 chr6:86648436 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.54 -9.61 -0.46 1.58e-19 Response to antipsychotic treatment; LIHC cis rs2073499 1.000 rs76846888 chr3:50406058 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.71 7.24 0.36 2.93e-12 Schizophrenia; LIHC cis rs881375 0.902 rs2900180 chr9:123706382 T/C cg14580859 chr9:123691850 NA 0.39 6.83 0.35 3.89e-11 Rheumatoid arthritis; LIHC trans rs526821 0.595 rs4938937 chr11:55305507 T/A cg15704280 chr7:45808275 SEPT13 -0.54 -8.37 -0.41 1.5e-15 Pediatric bone mineral density (spine); LIHC cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.2 0.45 3.6e-18 Bipolar disorder; LIHC cis rs28829049 0.597 rs12745238 chr1:19393710 C/T cg18202521 chr1:19600702 AKR7L -0.37 -6.33 -0.32 7.77e-10 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs2204008 0.744 rs11180504 chr12:38236313 C/T cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs5769765 0.955 rs2295406 chr22:50260169 G/A cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs936229 0.651 rs12908814 chr15:75132490 C/G cg14664628 chr15:75095509 CSK -0.56 -8.83 -0.43 5.37e-17 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs9811920 0.638 rs796978 chr3:99564321 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.4 -5.77 -0.3 1.75e-8 Axial length; LIHC cis rs11167764 1.000 rs11167764 chr5:141479065 A/C cg23435118 chr5:141488016 NDFIP1 -0.43 -5.98 -0.31 5.61e-9 Crohn's disease; LIHC trans rs2727020 0.704 rs2988340 chr11:49176057 C/T cg03929089 chr4:120376271 NA -0.75 -12.96 -0.57 1.64e-31 Coronary artery disease; LIHC cis rs10484885 0.824 rs11967579 chr6:90540008 G/T cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.81 -0.35 4.27e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs11719291 0.833 rs11709246 chr3:48859498 G/A cg07636037 chr3:49044803 WDR6 -0.79 -7.76 -0.39 9.98e-14 Cognitive function; LIHC cis rs6963495 0.818 rs73192122 chr7:105171471 G/A cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs13191362 1.000 rs13204013 chr6:163002480 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Bipolar disorder; LIHC cis rs7520050 0.966 rs61102033 chr1:46382441 G/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.6e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs1799949 0.965 rs799908 chr17:41278916 A/G cg25072359 chr17:41440525 NA 0.38 6.01 0.31 4.72e-9 Menopause (age at onset); LIHC cis rs17818399 0.597 rs13385693 chr2:46867158 C/T cg02822958 chr2:46747628 ATP6V1E2 0.36 5.72 0.3 2.29e-8 Height; LIHC cis rs3770081 0.590 rs60785155 chr2:86452798 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.71 -7.51 -0.38 5.31e-13 Facial emotion recognition (sad faces); LIHC cis rs7666738 0.791 rs62318641 chr4:98816964 T/C cg05340658 chr4:99064831 C4orf37 0.62 11.24 0.52 3.65e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs7584330 0.826 rs7604315 chr2:238381729 C/G cg14458575 chr2:238380390 NA 0.42 6.45 0.33 3.87e-10 Prostate cancer; LIHC cis rs60871478 0.545 rs35400476 chr7:795686 A/G cg05535760 chr7:792225 HEATR2 0.8 10.91 0.51 5.64e-24 Cerebrospinal P-tau181p levels; LIHC cis rs9911578 0.835 rs9889419 chr17:56473259 C/T cg05425664 chr17:57184151 TRIM37 -0.57 -8.33 -0.41 1.94e-15 Intelligence (multi-trait analysis); LIHC cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg20887711 chr4:1340912 KIAA1530 0.54 7.87 0.39 4.76e-14 Longevity; LIHC trans rs11098499 0.863 rs11731756 chr4:120478696 T/G cg25214090 chr10:38739885 LOC399744 0.59 9.36 0.45 1.08e-18 Corneal astigmatism; LIHC cis rs4474465 0.915 rs10128737 chr11:78186687 G/A cg02023728 chr11:77925099 USP35 0.34 6.03 0.31 4.14e-9 Alzheimer's disease (survival time); LIHC cis rs7208859 0.528 rs3764416 chr17:28900708 G/T cg14067834 chr17:29058358 SUZ12P -0.62 -5.99 -0.31 5.32e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9341808 0.935 rs942381 chr6:80880150 T/G cg08355045 chr6:80787529 NA 0.31 5.92 0.3 7.87e-9 Sitting height ratio; LIHC cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg17971929 chr21:40555470 PSMG1 0.77 9.25 0.45 2.44e-18 Cognitive function; LIHC cis rs6964587 0.869 rs13237856 chr7:91551788 G/A cg17063962 chr7:91808500 NA -0.96 -18.04 -0.7 1.31e-51 Breast cancer; LIHC cis rs870825 0.655 rs67380800 chr4:185623788 T/C cg04058563 chr4:185651563 MLF1IP 0.77 7.67 0.38 1.81e-13 Blood protein levels; LIHC cis rs2273156 1.000 rs8018114 chr14:35470019 T/C cg16230307 chr14:35515116 FAM177A1 -0.41 -6.05 -0.31 3.88e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.75 -0.5 2e-23 Platelet count; LIHC cis rs3008870 1.000 rs2815370 chr1:67503727 A/G cg02640540 chr1:67518911 SLC35D1 -0.48 -6.52 -0.33 2.57e-10 Lymphocyte percentage of white cells; LIHC cis rs11229555 0.645 rs7929868 chr11:58209418 C/T cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs12477438 0.798 rs896886 chr2:99652713 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 11.24 0.52 3.65e-25 Chronic sinus infection; LIHC cis rs611744 0.647 rs2594358 chr8:109256018 A/G cg18478394 chr8:109455254 TTC35 0.4 6.95 0.35 1.85e-11 Dupuytren's disease; LIHC cis rs7520050 0.807 rs6429576 chr1:46216575 T/C cg03146154 chr1:46216737 IPP 0.48 8.08 0.4 1.12e-14 Red blood cell count;Reticulocyte count; LIHC cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg24531977 chr5:56204891 C5orf35 -0.66 -9.46 -0.46 5.3e-19 Type 2 diabetes; LIHC cis rs1707322 0.752 rs12024590 chr1:46127496 A/C cg06784218 chr1:46089804 CCDC17 0.41 7.49 0.38 5.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25237692 chr15:64752785 NA 0.4 6.16 0.32 2.1e-9 Lung function (FEV1/FVC); LIHC cis rs6461049 0.800 rs3800913 chr7:2163237 A/G cg21782813 chr7:2030301 MAD1L1 0.37 6.42 0.33 4.45e-10 Schizophrenia; LIHC cis rs7089973 0.604 rs2181563 chr10:116604344 T/C cg03647239 chr10:116582469 FAM160B1 0.46 6.67 0.34 1.05e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7149337 0.836 rs4901087 chr14:51668499 T/C cg23942311 chr14:51606299 NA 0.33 6.51 0.33 2.76e-10 Cancer; LIHC cis rs3784262 0.967 rs12910752 chr15:58314679 G/A cg12031962 chr15:58353849 ALDH1A2 -0.34 -6.71 -0.34 8.24e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs2439831 0.867 rs486301 chr15:43836949 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.54 7.26 0.37 2.71e-12 Lung cancer in ever smokers; LIHC cis rs4065321 0.609 rs8075668 chr17:38137623 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.71 12.95 0.57 1.78e-31 White blood cell count (basophil);White blood cell count; LIHC cis rs7772486 0.701 rs7772717 chr6:145954854 T/C cg13319975 chr6:146136371 FBXO30 -0.4 -6.67 -0.34 1.04e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg05255149 chr17:80675120 FN3KRP 0.45 6.51 0.33 2.71e-10 Glycated hemoglobin levels; LIHC cis rs965469 0.619 rs6037565 chr20:3330308 T/C cg25506879 chr20:3388711 C20orf194 -0.53 -6.54 -0.33 2.22e-10 IFN-related cytopenia; LIHC cis rs904251 0.861 rs1757180 chr6:37486145 T/C cg08126542 chr6:37504118 NA -0.38 -5.89 -0.3 9.16e-9 Cognitive performance; LIHC cis rs2153535 0.580 rs6597327 chr6:8482157 G/A cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg06634786 chr22:41940651 POLR3H -0.64 -7.06 -0.36 9.24e-12 Vitiligo; LIHC cis rs910316 1.000 rs175443 chr14:75601963 C/T cg08847533 chr14:75593920 NEK9 -0.87 -18.88 -0.71 5.42e-55 Height; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg08514994 chr20:47805136 STAU1 -0.44 -6.1 -0.31 2.91e-9 Migraine with aura; LIHC cis rs17685 0.712 rs59659102 chr7:75710114 G/A cg01364799 chr7:75623366 TMEM120A -0.48 -7.2 -0.36 3.79e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11098499 0.863 rs7669520 chr4:120515278 T/C cg09307838 chr4:120376055 NA 0.75 11.81 0.54 3.06e-27 Corneal astigmatism; LIHC cis rs8017423 0.935 rs11624295 chr14:90695612 T/G cg14092571 chr14:90743983 NA -0.37 -5.76 -0.3 1.9e-8 Mortality in heart failure; LIHC cis rs4665809 1.000 rs2384323 chr2:26306473 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.69 -0.43 1.58e-16 Gut microbiome composition (summer); LIHC cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg25364880 chr3:44379878 C3orf23 0.53 7.1 0.36 7.12e-12 Depressive symptoms; LIHC cis rs765787 0.530 rs2433227 chr15:45517119 A/T cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC cis rs6918586 0.658 rs198844 chr6:26108282 C/G cg18357526 chr6:26021779 HIST1H4A -0.54 -7.95 -0.39 2.73e-14 Schizophrenia; LIHC cis rs860295 0.812 rs2297775 chr1:155735012 C/T cg02153340 chr1:155202674 NA 0.34 6.4 0.33 5.04e-10 Body mass index; LIHC cis rs2075165 0.901 rs7542798 chr1:156224304 A/G cg20302342 chr1:156215951 PAQR6 0.32 6.2 0.32 1.63e-9 Tonsillectomy; LIHC cis rs60871478 0.545 rs35400476 chr7:795686 A/G cg04727924 chr7:799746 HEATR2 -0.56 -7.98 -0.4 2.19e-14 Cerebrospinal P-tau181p levels; LIHC cis rs4654899 0.758 rs3820326 chr1:21277141 G/A cg08539965 chr1:21396338 EIF4G3 0.34 6.15 0.32 2.22e-9 Superior frontal gyrus grey matter volume; LIHC cis rs9790314 0.875 rs7615592 chr3:160981548 A/C cg03342759 chr3:160939853 NMD3 -0.74 -8.83 -0.43 5.39e-17 Morning vs. evening chronotype; LIHC trans rs61931739 0.500 rs10772160 chr12:34456848 G/A cg26384229 chr12:38710491 ALG10B 0.64 8.13 0.4 8.12e-15 Morning vs. evening chronotype; LIHC cis rs2073300 1.000 rs6036411 chr20:23441706 A/C cg12062639 chr20:23401060 NAPB 0.85 10.27 0.49 9.9700000000000009e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7772486 0.754 rs4896838 chr6:146015451 T/C cg13319975 chr6:146136371 FBXO30 0.47 7.49 0.38 5.74e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs9393692 0.645 rs2179152 chr6:26325888 T/C cg13736514 chr6:26305472 NA -0.4 -6.23 -0.32 1.4e-9 Educational attainment; LIHC cis rs875971 0.965 rs9969301 chr7:65781655 G/A cg11764359 chr7:65958608 NA -0.91 -16.91 -0.67 4.78e-47 Aortic root size; LIHC cis rs11122272 0.735 rs973253 chr1:231520874 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs9399135 0.967 rs9373122 chr6:135373534 G/A cg24558204 chr6:135376177 HBS1L 0.44 7.14 0.36 5.57e-12 Red blood cell count; LIHC cis rs933688 0.526 rs2973468 chr5:90540879 A/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.47 -6.48 -0.33 3.26e-10 Smoking behavior; LIHC cis rs7945705 0.747 rs1980429 chr11:9010474 C/A cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -7.34 -0.37 1.62e-12 Hemoglobin concentration; LIHC cis rs12908161 1.000 rs35316992 chr15:85248133 A/G cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC cis rs67460515 0.892 rs11710489 chr3:161093332 G/A cg17135325 chr3:160939158 NMD3 0.54 7.68 0.38 1.71e-13 Parkinson's disease; LIHC cis rs7647973 0.626 rs4855833 chr3:49657441 A/G cg03060546 chr3:49711283 APEH 0.59 6.78 0.34 5.41e-11 Menarche (age at onset); LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg14828511 chr1:107599125 PRMT6 -0.42 -6.01 -0.31 4.79e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9814567 1.000 rs7356093 chr3:134238753 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9300255 0.544 rs1727309 chr12:123658258 A/G cg00376283 chr12:123451042 ABCB9 0.59 5.85 0.3 1.17e-8 Neutrophil percentage of white cells; LIHC cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg02931644 chr1:25747376 RHCE 0.36 7.79 0.39 7.95e-14 Plateletcrit;Mean corpuscular volume; LIHC cis rs243505 0.660 rs10274701 chr7:148552456 C/T cg09806900 chr7:148480153 CUL1 0.43 6.17 0.32 1.92e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs35110281 0.748 rs162403 chr21:44963365 C/G cg21573476 chr21:45109991 RRP1B -0.57 -10.57 -0.5 8.68e-23 Mean corpuscular volume; LIHC cis rs2033908 0.620 rs10765996 chr11:12853043 A/G cg25843174 chr11:12811716 TEAD1 -0.32 -7.21 -0.36 3.71e-12 Sitting height ratio; LIHC cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg13047869 chr3:10149882 C3orf24 0.51 6.63 0.34 1.29e-10 Alzheimer's disease; LIHC cis rs7715806 0.500 rs17563589 chr5:74980019 A/G cg00601450 chr5:74908170 NA 0.59 7.18 0.36 4.27e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2838344 0.776 rs2298561 chr21:45085234 A/G cg21573476 chr21:45109991 RRP1B -0.59 -11.15 -0.52 7.63e-25 Coronary artery disease; LIHC cis rs7927592 0.913 rs7104345 chr11:68316772 G/A cg01657329 chr11:68192670 LRP5 -0.47 -6.15 -0.32 2.22e-9 Total body bone mineral density; LIHC cis rs11098499 0.675 rs11098534 chr4:120556772 T/G cg09307838 chr4:120376055 NA 0.66 10.21 0.48 1.59e-21 Corneal astigmatism; LIHC cis rs1475911 0.708 rs8129075 chr21:43523430 G/T cg19766460 chr21:43528205 UMODL1;C21orf128 1.13 18.64 0.71 5.42e-54 IgG glycosylation; LIHC cis rs5753618 0.561 rs2078803 chr22:31652852 G/A cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC trans rs11098499 0.954 rs12506546 chr4:120301618 T/C cg25214090 chr10:38739885 LOC399744 0.56 8.84 0.43 5.07e-17 Corneal astigmatism; LIHC cis rs4805272 0.539 rs11883172 chr19:29318536 C/T cg04546413 chr19:29218101 NA 0.43 7.12 0.36 6.24e-12 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs853679 0.517 rs9380058 chr6:28127444 T/C cg16479474 chr6:28041457 NA 0.45 6.45 0.33 3.72e-10 Depression; LIHC cis rs2404602 1.000 rs1117367 chr15:76872330 A/C cg03037974 chr15:76606532 NA 0.71 13.86 0.6 5.53e-35 Blood metabolite levels; LIHC cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg04944784 chr2:26401820 FAM59B 0.7 9.09 0.44 8.25e-18 Gut microbiome composition (summer); LIHC cis rs12134245 0.719 rs61798831 chr1:91996588 C/T cg07090678 chr1:91966139 CDC7 0.51 7.01 0.35 1.29e-11 Breast cancer; LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg02290350 chr8:58132656 NA 0.5 10.64 0.5 5.15e-23 Developmental language disorder (linguistic errors); LIHC cis rs2242116 0.727 rs6442040 chr3:46963035 C/A cg23352942 chr3:46931381 PTH1R -0.27 -6.75 -0.34 6.26e-11 Birth weight; LIHC cis rs916888 0.610 rs199529 chr17:44837217 A/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.65 6.27 0.32 1.11e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg16414030 chr3:133502952 NA -0.4 -6.27 -0.32 1.09e-9 Iron status biomarkers; LIHC cis rs1215050 0.791 rs1648546 chr4:98899294 T/C cg05340658 chr4:99064831 C4orf37 -0.39 -5.76 -0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6088590 0.965 rs6119534 chr20:33441257 C/T cg24642439 chr20:33292090 TP53INP2 0.74 9.78 0.47 4.6e-20 Coronary artery disease; LIHC cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg06481639 chr22:41940642 POLR3H 0.67 6.76 0.34 5.87e-11 Vitiligo; LIHC cis rs425277 0.628 rs262668 chr1:2082602 A/G cg03732007 chr1:2071316 PRKCZ 0.35 6.08 0.31 3.21e-9 Height; LIHC cis rs7017697 0.793 rs7018235 chr8:19682698 C/T cg03894339 chr8:19674705 INTS10 0.39 5.74 0.3 2.09e-8 Breast cancer; LIHC cis rs151997 0.671 rs3991902 chr5:50203749 A/T cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14331148 chr19:47551893 TMEM160 -0.48 -6.39 -0.33 5.35e-10 Pancreatic cancer; LIHC cis rs546131 0.642 rs512013 chr11:34842225 C/T cg06937548 chr11:34938143 PDHX;APIP 0.56 7.2 0.36 3.82e-12 Lung disease severity in cystic fibrosis; LIHC cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg18404041 chr3:52824283 ITIH1 -0.58 -9.65 -0.46 1.16e-19 Electroencephalogram traits; LIHC cis rs3796352 1.000 rs2336540 chr3:52974589 G/A cg07884673 chr3:53033167 SFMBT1 0.88 6.5 0.33 2.77e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs9905704 0.624 rs4932691 chr17:57094617 T/C cg12560992 chr17:57184187 TRIM37 -0.68 -10.1 -0.48 3.64e-21 Testicular germ cell tumor; LIHC trans rs62103177 0.535 rs4799109 chr18:77675188 A/T cg05926928 chr17:57297772 GDPD1 0.83 9.44 0.45 5.83e-19 Opioid sensitivity; LIHC cis rs3892630 0.588 rs2112917 chr19:33317543 C/T cg22980127 chr19:33182716 NUDT19 1.03 13.51 0.59 1.26e-33 Red blood cell traits; LIHC cis rs6951245 1.000 rs6951245 chr7:1058193 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -6.06 -0.31 3.53e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6448317 0.863 rs2695228 chr4:24901985 C/T cg21108841 chr4:24914750 CCDC149 0.54 7.91 0.39 3.53e-14 Heschl's gyrus morphology; LIHC cis rs11122272 0.735 rs2474633 chr1:231486989 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.94 -0.51 4.54e-24 Hemoglobin concentration; LIHC cis rs6733011 0.578 rs4851170 chr2:99504323 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.44 6.43 0.33 4.33e-10 Bipolar disorder; LIHC cis rs12048904 0.533 rs1590580 chr1:101292668 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.58 9.51 0.46 3.45e-19 Multiple sclerosis; LIHC cis rs7582180 0.577 rs6542942 chr2:100985378 G/T cg14675211 chr2:100938903 LONRF2 0.56 8.36 0.41 1.57e-15 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg06634786 chr22:41940651 POLR3H 0.83 8.89 0.43 3.5e-17 Vitiligo; LIHC cis rs8014204 0.839 rs6574197 chr14:75331487 A/G cg08847533 chr14:75593920 NEK9 -0.37 -6.05 -0.31 3.78e-9 Caffeine consumption; LIHC cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg27170947 chr2:26402098 FAM59B -0.65 -8.36 -0.41 1.57e-15 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg20607798 chr8:58055168 NA 0.7 8.52 0.42 4.99e-16 Developmental language disorder (linguistic errors); LIHC cis rs747782 0.646 rs17198158 chr11:47477849 A/G cg20307385 chr11:47447363 PSMC3 -0.55 -6.35 -0.32 6.99e-10 Intraocular pressure; LIHC cis rs16828019 0.929 rs2363805 chr1:41719434 G/T cg03387723 chr1:41708464 SCMH1 -0.44 -7.21 -0.36 3.66e-12 Intelligence (multi-trait analysis); LIHC cis rs2274273 0.967 rs8009670 chr14:55583477 G/A cg01864836 chr14:55583639 NA -0.44 -8.71 -0.43 1.28e-16 Protein biomarker; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06253862 chr6:160201362 SNORA20;TCP1 0.41 6.24 0.32 1.3e-9 Longevity; LIHC cis rs138880 0.542 rs9616371 chr22:50306338 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.87 -7.64 -0.38 2.2e-13 Schizophrenia; LIHC cis rs7412746 0.658 rs59988025 chr1:150940358 C/T cg18016565 chr1:150552671 MCL1 0.51 9.67 0.46 1.03e-19 Melanoma; LIHC cis rs4665809 0.838 rs2243834 chr2:26357748 A/C cg26119090 chr2:26468346 HADHA;HADHB 0.68 8.84 0.43 5.21e-17 Gut microbiome composition (summer); LIHC cis rs2204008 0.744 rs11180504 chr12:38236313 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC cis rs1000083 0.666 rs1609327 chr5:96633109 G/A ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs13191362 1.000 rs73016459 chr6:163066323 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.77 6.74 0.34 6.68e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11758351 0.715 rs76130408 chr6:26208962 A/G cg03854865 chr6:26224070 HIST1H3E 0.59 6.43 0.33 4.36e-10 Gout;Renal underexcretion gout; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08365438 chr10:21683093 NA 0.42 6.04 0.31 4.02e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6951245 0.938 rs112425403 chr7:1071531 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.75e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10744422 0.800 rs2343110 chr12:123343571 T/G cg07706471 chr12:123319906 HIP1R -0.62 -8.26 -0.41 3.29e-15 Schizophrenia; LIHC cis rs11122272 0.735 rs973254 chr1:231521149 T/A cg06096015 chr1:231504339 EGLN1 0.51 9.46 0.46 5.23e-19 Hemoglobin concentration; LIHC cis rs8072100 1.000 rs8072100 chr17:45674687 A/T cg25173405 chr17:45401733 C17orf57 0.42 5.75 0.3 1.98e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs3768617 0.510 rs7549768 chr1:183097382 T/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.57e-22 Fuchs's corneal dystrophy; LIHC trans rs17685 0.753 rs4728586 chr7:75802869 T/C cg19862616 chr7:65841803 NCRNA00174 0.94 19.24 0.72 2.06e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6545883 0.894 rs12622458 chr2:61523554 A/C cg14146966 chr2:61757674 XPO1 -0.42 -7.16 -0.36 4.83e-12 Tuberculosis; LIHC cis rs7914558 0.966 rs7096269 chr10:104736721 A/G cg15744005 chr10:104629667 AS3MT -0.41 -9.47 -0.46 4.73e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15357518 chr19:36120356 RBM42 0.51 8.07 0.4 1.25e-14 Pancreatic cancer; LIHC cis rs7312933 0.524 rs11181465 chr12:42765098 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 8.0 0.4 1.88e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs2066819 1.000 rs79436528 chr12:56686997 C/T cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg10755058 chr3:40428713 ENTPD3 -0.41 -7.14 -0.36 5.64e-12 Renal cell carcinoma; LIHC cis rs798554 1.000 rs798554 chr7:2759795 C/T cg04166393 chr7:2884313 GNA12 0.42 5.81 0.3 1.44e-8 Height; LIHC cis rs7659604 0.539 rs56159666 chr4:122782879 G/A cg20573242 chr4:122745356 CCNA2 0.53 7.75 0.39 1.07e-13 Type 2 diabetes; LIHC cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg27121462 chr16:89883253 FANCA -0.46 -7.38 -0.37 1.21e-12 Vitiligo; LIHC cis rs6062302 0.522 rs6090475 chr20:62245397 C/A cg09650180 chr20:62225654 GMEB2 -0.38 -6.05 -0.31 3.87e-9 Glioblastoma; LIHC cis rs4555082 0.874 rs2015978 chr14:105720134 G/C cg06808227 chr14:105710500 BRF1 -0.55 -7.21 -0.36 3.58e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg19318889 chr4:1322082 MAEA 0.65 10.37 0.49 4.24e-22 Longevity; LIHC cis rs2832191 0.646 rs2832214 chr21:30517127 C/T cg24692254 chr21:30365293 RNF160 -0.42 -6.59 -0.34 1.69e-10 Dental caries; LIHC cis rs6723226 0.842 rs1901355 chr2:32835664 A/G cg02381751 chr2:32503542 YIPF4 -0.71 -10.33 -0.49 5.77e-22 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.955 rs11719205 chr3:40417258 G/A cg24209194 chr3:40518798 ZNF619 0.42 5.94 0.31 7.2e-9 Renal cell carcinoma; LIHC cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg09222892 chr1:25734099 RHCE -0.46 -8.45 -0.42 8.62e-16 Erythrocyte sedimentation rate; LIHC cis rs7772486 0.754 rs702324 chr6:146008793 A/G cg23711669 chr6:146136114 FBXO30 -0.62 -9.21 -0.45 3.31e-18 Lobe attachment (rater-scored or self-reported); LIHC trans rs561341 1.000 rs72821971 chr17:30269343 T/G cg20587970 chr11:113659929 NA -1.46 -11.99 -0.54 6.92e-28 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.679 rs7840100 chr8:58036662 T/G cg02290350 chr8:58132656 NA 0.31 7.15 0.36 5.41e-12 Developmental language disorder (linguistic errors); LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.99 20.94 0.75 3.08e-63 Height; LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.95 -0.31 6.52e-9 Total body bone mineral density; LIHC cis rs7264396 0.563 rs6058312 chr20:34324484 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.47e-16 Total cholesterol levels; LIHC cis rs1144333 1.000 rs12082448 chr1:76353225 C/T cg22875332 chr1:76189707 ACADM 0.42 6.54 0.33 2.3e-10 Attention function in attention deficit hyperactive disorder; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15209934 chr19:52800385 ZNF480 0.45 6.11 0.31 2.66e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2380220 0.606 rs7754906 chr6:95992429 C/T cg23517279 chr6:96025343 MANEA 0.55 6.32 0.32 8.37e-10 Behavioural disinhibition (generation interaction); LIHC cis rs11676348 0.818 rs7426289 chr2:218966315 C/T cg00012203 chr2:219082015 ARPC2 -0.53 -7.29 -0.37 2.12e-12 Ulcerative colitis; LIHC cis rs1552244 0.882 rs13066757 chr3:10045030 C/A cg00149659 chr3:10157352 C3orf10 0.53 5.99 0.31 5.32e-9 Alzheimer's disease; LIHC cis rs2191566 1.000 rs2191566 chr19:44511389 A/C cg20607764 chr19:44506953 ZNF230 0.45 7.31 0.37 1.86e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs908922 0.676 rs533917 chr1:152518294 A/G cg20991723 chr1:152506922 NA 0.53 8.94 0.44 2.47e-17 Hair morphology; LIHC cis rs6964587 1.000 rs2282971 chr7:91584356 A/G cg17063962 chr7:91808500 NA 0.97 19.28 0.72 1.44e-56 Breast cancer; LIHC cis rs4819052 0.851 rs2838856 chr21:46680766 T/G cg11663144 chr21:46675770 NA -0.3 -5.75 -0.3 1.97e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg25364880 chr3:44379878 C3orf23 0.57 7.8 0.39 7.71e-14 Depressive symptoms; LIHC trans rs916888 0.773 rs538628 chr17:44787313 G/C cg16836995 chr17:43662488 NA -0.75 -7.68 -0.38 1.67e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs3857067 0.806 rs72665627 chr4:95111824 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs908922 0.676 rs539393 chr1:152518896 C/T cg20991723 chr1:152506922 NA 0.54 9.07 0.44 9.25e-18 Hair morphology; LIHC cis rs600806 0.815 rs3768495 chr1:109935325 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09497769 chr2:24248384 NA 0.45 6.34 0.32 7.17e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9902453 1.000 rs9897206 chr17:28406108 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.92 -0.54 1.22e-27 Coffee consumption (cups per day); LIHC cis rs7607369 0.580 rs17573731 chr2:219652153 T/C cg02176678 chr2:219576539 TTLL4 -0.43 -5.73 -0.3 2.26e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs6748734 0.901 rs6720357 chr2:241830296 A/C cg04034577 chr2:241836375 C2orf54 -0.4 -8.11 -0.4 9.08e-15 Urinary metabolites; LIHC cis rs6430585 0.528 rs75524146 chr2:136725459 C/T cg07305463 chr2:136567211 LCT -0.38 -5.82 -0.3 1.38e-8 Corneal structure; LIHC cis rs9814567 0.752 rs7623567 chr3:134330976 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs55882075 0.634 rs12518476 chr5:179110850 A/G cg14593053 chr5:179126677 CANX 0.39 6.85 0.35 3.35e-11 Monocyte percentage of white cells; LIHC cis rs9393692 0.905 rs9393694 chr6:26279296 T/C cg00631329 chr6:26305371 NA -0.43 -7.25 -0.36 2.88e-12 Educational attainment; LIHC cis rs9486719 0.895 rs3734239 chr6:96996244 A/G cg06623918 chr6:96969491 KIAA0776 -0.72 -7.23 -0.36 3.08e-12 Migraine;Coronary artery disease; LIHC cis rs7772486 0.790 rs1854900 chr6:146331382 G/A cg13319975 chr6:146136371 FBXO30 -0.37 -6.09 -0.31 2.98e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 0.755 rs10789219 chr1:67417742 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.65 0.5 4.76e-23 Lymphocyte percentage of white cells; LIHC cis rs2274273 0.624 rs11848456 chr14:55755392 A/G cg01864836 chr14:55583639 NA -0.36 -5.95 -0.31 6.6e-9 Protein biomarker; LIHC trans rs877282 0.629 rs78997110 chr10:764388 A/G cg22713356 chr15:30763199 NA 1.44 11.86 0.54 2.03e-27 Uric acid levels; LIHC cis rs769267 0.896 rs10410664 chr19:19556651 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.16e-9 Tonsillectomy; LIHC cis rs796364 0.806 rs203767 chr2:200902411 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs898097 0.812 rs56274787 chr17:80862682 C/T cg15664640 chr17:80829946 TBCD -0.77 -12.67 -0.57 1.94e-30 Breast cancer; LIHC cis rs9828933 0.938 rs7617036 chr3:64002995 G/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.77 -9.64 -0.46 1.26e-19 Type 2 diabetes; LIHC cis rs477895 0.838 rs11607007 chr11:64007976 C/T cg05555928 chr11:63887634 MACROD1 0.48 6.23 0.32 1.34e-9 Mean platelet volume; LIHC cis rs9921222 0.692 rs11860497 chr16:405416 A/G cg26913058 chr16:419975 MRPL28 -0.51 -7.88 -0.39 4.41e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs3857067 0.806 rs2865343 chr4:95103005 C/T cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.79 -0.39 8.19e-14 QT interval; LIHC cis rs9303401 0.659 rs11079358 chr17:56920949 G/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.84 0.43 5.15e-17 Cognitive test performance; LIHC cis rs713477 1.000 rs12888234 chr14:55911352 T/A cg13175173 chr14:55914753 NA -0.35 -8.16 -0.4 6.31e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs965469 1.000 rs6051722 chr20:3274435 A/G cg25506879 chr20:3388711 C20orf194 -0.6 -7.17 -0.36 4.77e-12 IFN-related cytopenia; LIHC cis rs172166 0.694 rs203892 chr6:28067196 T/C cg16479474 chr6:28041457 NA 0.39 6.68 0.34 9.59e-11 Cardiac Troponin-T levels; LIHC cis rs10088262 0.629 rs1367829 chr8:124797135 A/G cg02993010 chr8:124780839 FAM91A1 -0.48 -6.22 -0.32 1.46e-9 Pancreatic cancer; LIHC cis rs7095944 0.614 rs10901818 chr10:126449428 G/A cg08799069 chr10:126477246 METTL10 -0.38 -6.75 -0.34 6.32e-11 Asthma; LIHC cis rs7208859 0.573 rs60724269 chr17:29113273 G/T cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs72843506 0.656 rs57040439 chr17:19939835 C/G cg12065943 chr17:19881925 AKAP10 -0.41 -6.93 -0.35 2.14e-11 Schizophrenia; LIHC cis rs10744422 1.000 rs3852536 chr12:123333824 C/T cg25930673 chr12:123319894 HIP1R -0.93 -12.38 -0.56 2.45e-29 Schizophrenia; LIHC cis rs875971 1.000 rs4718343 chr7:65874288 T/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs798554 0.686 rs7777484 chr7:2814271 A/G cg13628971 chr7:2884303 GNA12 0.43 6.76 0.34 6.07e-11 Height; LIHC cis rs763121 0.853 rs4820345 chr22:39091151 T/C cg14440974 chr22:39074834 NA -0.46 -7.37 -0.37 1.29e-12 Menopause (age at onset); LIHC cis rs875971 0.825 rs66981195 chr7:66079035 C/A cg18252515 chr7:66147081 NA 0.45 6.56 0.33 1.97e-10 Aortic root size; LIHC cis rs3806843 0.897 rs2531338 chr5:140136957 A/T cg26395211 chr5:140044315 WDR55 0.4 5.89 0.3 9.1e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs6934970 1.000 rs62413975 chr6:113059510 T/G cg09308777 chr6:169852575 NA 0.58 6.06 0.31 3.67e-9 Bipolar disorder (body mass index interaction); LIHC cis rs2197308 0.605 rs2387437 chr12:37919367 T/C cg26384229 chr12:38710491 ALG10B 0.81 10.43 0.49 2.66e-22 Morning vs. evening chronotype; LIHC cis rs6594499 0.872 rs1379300 chr5:110441439 A/G cg04022379 chr5:110408740 TSLP 0.49 8.14 0.4 7.64e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7607369 0.791 rs12468043 chr2:219354197 C/A cg02176678 chr2:219576539 TTLL4 0.52 7.09 0.36 7.61e-12 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs736408 0.716 rs2239549 chr3:52823126 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.2 0.36 3.93e-12 Bipolar disorder; LIHC cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.52 0.53 3.63e-26 Alzheimer's disease; LIHC cis rs2933343 0.700 rs789240 chr3:128630635 T/C cg25356066 chr3:128598488 ACAD9 0.53 7.47 0.37 6.95e-13 IgG glycosylation; LIHC cis rs2228479 0.541 rs12918575 chr16:89811151 A/G cg19635926 chr16:89946313 TCF25 0.46 5.99 0.31 5.24e-9 Skin colour saturation; LIHC trans rs975809 0.966 rs11004607 chr10:56622686 G/T cg15219393 chr5:149109878 PPARGC1B -0.43 -6.06 -0.31 3.59e-9 Carotid intima media thickness; LIHC cis rs2204008 0.743 rs11495614 chr12:38156358 C/T cg26384229 chr12:38710491 ALG10B 0.77 8.97 0.44 2.06e-17 Bladder cancer; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg06420487 chr17:61919686 SMARCD2 -0.43 -5.88 -0.3 9.92e-9 Height; LIHC cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg13397359 chr6:42928475 GNMT 0.79 11.3 0.52 2.19e-25 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9303401 0.614 rs12947982 chr17:57140301 A/G cg25039879 chr17:56429692 SUPT4H1 0.75 8.68 0.42 1.66e-16 Cognitive test performance; LIHC trans rs7618501 1.000 rs6775384 chr3:49853073 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.79 13.85 0.6 6.2e-35 Intelligence (multi-trait analysis); LIHC cis rs763121 0.853 rs6001184 chr22:39052116 C/T cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs780096 0.546 rs2293571 chr2:27729480 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.49 -0.33 3.04e-10 Total body bone mineral density; LIHC cis rs6582630 0.519 rs10880629 chr12:38533611 T/G cg13010199 chr12:38710504 ALG10B 0.45 6.12 0.31 2.61e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs250677 0.652 rs250675 chr5:148438565 A/C cg12140854 chr5:148520817 ABLIM3 0.52 6.1 0.31 2.85e-9 Breast cancer; LIHC cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.74e-10 Diabetic kidney disease; LIHC cis rs7762018 0.891 rs3749882 chr6:170151766 C/T cg19338460 chr6:170058176 WDR27 -0.38 -5.8 -0.3 1.47e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11190604 1.000 rs2489034 chr10:102319192 C/T cg07080220 chr10:102295463 HIF1AN 0.52 7.2 0.36 3.78e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1008375 0.800 rs35463363 chr4:17613423 G/T cg16339924 chr4:17578868 LAP3 0.54 7.15 0.36 5.38e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12497850 0.931 rs7636057 chr3:48992582 C/T cg06212747 chr3:49208901 KLHDC8B 0.56 7.19 0.36 4.06e-12 Parkinson's disease; LIHC cis rs7827545 1.000 rs7827545 chr8:135566567 C/T cg09855544 chr8:135498122 ZFAT 0.45 7.75 0.39 1.07e-13 Hypertension (SNP x SNP interaction); LIHC cis rs1707322 0.656 rs9429172 chr1:46092476 C/G cg06784218 chr1:46089804 CCDC17 -0.42 -7.59 -0.38 3.17e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs929354 0.772 rs6957939 chr7:156978485 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs2637266 0.783 rs846647 chr10:78515508 C/G cg18941641 chr10:78392320 NA 0.27 5.84 0.3 1.22e-8 Pulmonary function; LIHC cis rs2204008 0.837 rs12581130 chr12:38319387 A/G cg26384229 chr12:38710491 ALG10B 0.55 7.59 0.38 3.12e-13 Bladder cancer; LIHC cis rs9583531 0.689 rs9521905 chr13:111352600 G/A cg15841412 chr13:111365552 ING1 -0.5 -6.06 -0.31 3.6e-9 Coronary artery disease; LIHC cis rs7267979 1.000 rs2259837 chr20:25280205 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs17102423 0.788 rs35176994 chr14:65596004 T/C cg11161011 chr14:65562177 MAX -0.48 -6.39 -0.33 5.53e-10 Obesity-related traits; LIHC cis rs10792665 0.735 rs10898064 chr11:82675897 A/G cg24227371 chr11:82718527 RAB30 -0.31 -7.51 -0.38 5.14e-13 Obesity-related traits; LIHC cis rs7216064 1.000 rs3206817 chr17:65892834 A/G cg12091567 chr17:66097778 LOC651250 -0.61 -8.55 -0.42 4.23e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs116095464 0.558 rs7731089 chr5:290422 A/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs7100689 0.784 rs10887838 chr10:82161380 G/A cg01528321 chr10:82214614 TSPAN14 0.91 13.29 0.58 9.07e-33 Post bronchodilator FEV1; LIHC cis rs477692 1.000 rs506274 chr10:131409392 T/A cg19680672 chr10:131412579 MGMT -0.45 -6.96 -0.35 1.74e-11 Response to temozolomide; LIHC cis rs1005277 0.579 rs2505198 chr10:38393183 A/C cg00409905 chr10:38381863 ZNF37A -0.59 -10.31 -0.49 6.75e-22 Extrinsic epigenetic age acceleration; LIHC cis rs4268898 0.722 rs11691212 chr2:24404733 A/G cg06627628 chr2:24431161 ITSN2 0.45 6.37 0.33 6.22e-10 Asthma; LIHC cis rs6912958 0.781 rs9450723 chr6:88226641 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.46 8.09 0.4 1.08e-14 Monocyte percentage of white cells; LIHC cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg05484376 chr2:27715224 FNDC4 0.36 6.09 0.31 3.04e-9 Total body bone mineral density; LIHC cis rs6570726 0.846 rs372904 chr6:145887425 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.98 -0.31 5.7e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6964587 0.967 rs4729015 chr7:91561592 T/G cg17063962 chr7:91808500 NA -1.02 -19.52 -0.73 1.47e-57 Breast cancer; LIHC cis rs7727544 0.735 rs272875 chr5:131674888 T/C cg07395648 chr5:131743802 NA -0.32 -6.57 -0.33 1.91e-10 Blood metabolite levels; LIHC cis rs9649465 1.000 rs10228367 chr7:123370903 C/T cg03229431 chr7:123269106 ASB15 -0.37 -7.99 -0.4 2.03e-14 Migraine; LIHC cis rs9303280 0.754 rs3816470 chr17:37985801 A/G cg11212589 chr17:38028394 ZPBP2 0.32 6.17 0.32 1.93e-9 Self-reported allergy; LIHC trans rs561341 0.660 rs7406043 chr17:30220152 C/G cg20587970 chr11:113659929 NA -0.73 -8.32 -0.41 2.12e-15 Hip circumference adjusted for BMI; LIHC cis rs8058578 0.633 rs113448632 chr16:30898219 C/T cg02466173 chr16:30829666 NA -0.44 -6.46 -0.33 3.59e-10 Multiple myeloma; LIHC cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs1030877 0.557 rs2278501 chr2:105979506 C/T cg02079111 chr2:105885981 TGFBRAP1 -0.51 -8.22 -0.41 4.22e-15 Obesity-related traits; LIHC cis rs10454142 0.961 rs10454143 chr2:48646400 G/T cg15846641 chr2:48541264 FOXN2 0.45 5.96 0.31 6.15e-9 Sex hormone-binding globulin levels; LIHC trans rs1814175 0.745 rs7483456 chr11:49774613 C/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.51 -0.79 2.04e-73 Height; LIHC cis rs10504229 0.906 rs113857287 chr8:58191683 T/C cg02290350 chr8:58132656 NA 0.41 8.36 0.41 1.65e-15 Developmental language disorder (linguistic errors); LIHC trans rs5756813 0.754 rs34848977 chr22:38165587 G/A cg19894588 chr14:64061835 NA -0.66 -9.1 -0.44 7.48e-18 Optic cup area;Vertical cup-disc ratio; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg06558623 chr16:89946397 TCF25 -0.86 -13.59 -0.59 6.08e-34 Skin colour saturation; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.66e-17 Prudent dietary pattern; LIHC trans rs61931739 0.571 rs4001689 chr12:34243271 C/T cg26384229 chr12:38710491 ALG10B 0.55 7.16 0.36 4.85e-12 Morning vs. evening chronotype; LIHC cis rs116095464 0.558 rs6881920 chr5:222411 T/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs9814567 0.896 rs6799110 chr3:134206749 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.34 -0.55 3.51e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10876993 0.715 rs2169987 chr12:58012111 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.43 5.9 0.3 8.83e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs7208859 0.623 rs7503335 chr17:29073962 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.33 0.41 1.98e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1577917 1.000 rs955227 chr6:86651032 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.01 -0.35 1.27e-11 Response to antipsychotic treatment; LIHC trans rs11039798 0.588 rs666165 chr11:48457439 C/T cg15704280 chr7:45808275 SEPT13 -0.58 -6.42 -0.33 4.57e-10 Axial length; LIHC cis rs7116495 0.867 rs612255 chr11:71778664 A/G cg26138937 chr11:71823887 C11orf51 -1.32 -10.43 -0.49 2.71e-22 Severe influenza A (H1N1) infection; LIHC cis rs12586317 0.586 rs74243590 chr14:35513246 G/A cg05294307 chr14:35346193 BAZ1A -0.49 -7.17 -0.36 4.52e-12 Psoriasis; LIHC cis rs4974559 0.895 rs10004411 chr4:1354306 T/G cg02980000 chr4:1222292 CTBP1 0.61 7.0 0.35 1.32e-11 Systolic blood pressure; LIHC cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg25894440 chr7:65020034 NA -0.52 -5.89 -0.3 9.49e-9 Diabetic kidney disease; LIHC cis rs17253792 0.822 rs78922774 chr14:56115302 T/A cg01858014 chr14:56050164 KTN1 -0.71 -7.26 -0.37 2.59e-12 Putamen volume; LIHC cis rs7917772 0.503 rs7893155 chr10:104294228 C/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.05 0.58 7.17e-32 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg11062466 chr8:58055876 NA 0.5 6.18 0.32 1.82e-9 Developmental language disorder (linguistic errors); LIHC trans rs916888 0.610 rs142167 chr17:44795234 C/T cg22968622 chr17:43663579 NA -0.49 -7.32 -0.37 1.77e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11122272 0.701 rs971533 chr1:231522097 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs6952808 0.825 rs34922657 chr7:1938655 C/T cg20295408 chr7:1910781 MAD1L1 -0.51 -7.11 -0.36 6.78e-12 Bipolar disorder and schizophrenia; LIHC cis rs4474465 0.646 rs6592794 chr11:78275743 A/G cg27205649 chr11:78285834 NARS2 0.5 7.81 0.39 7.29e-14 Alzheimer's disease (survival time); LIHC cis rs17270561 0.562 rs12199626 chr6:26013604 G/A cg17691542 chr6:26056736 HIST1H1C 1.02 12.86 0.57 3.71e-31 Iron status biomarkers; LIHC cis rs4268898 1.000 rs2303294 chr2:24432620 A/G cg06627628 chr2:24431161 ITSN2 0.51 7.38 0.37 1.2e-12 Asthma; LIHC cis rs6430585 0.527 rs1438303 chr2:136429857 C/T cg07169764 chr2:136633963 MCM6 0.68 8.71 0.43 1.31e-16 Corneal structure; LIHC cis rs6748734 1.000 rs10933518 chr2:241838091 A/C cg08694578 chr2:241835147 C2orf54 -0.63 -10.15 -0.48 2.48e-21 Urinary metabolites; LIHC cis rs1707322 0.964 rs1707339 chr1:46513179 A/G cg06784218 chr1:46089804 CCDC17 -0.36 -6.5 -0.33 2.8e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7131987 0.650 rs11050188 chr12:29473108 A/C cg05697976 chr12:29376483 FAR2 0.3 6.05 0.31 3.9e-9 QT interval; LIHC trans rs4596713 0.508 rs7467352 chr9:71766081 G/A cg16512924 chr15:28394682 HERC2 0.4 6.41 0.33 4.8e-10 Headache; LIHC cis rs7847628 0.765 rs7026635 chr9:123550027 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.67 -9.74 -0.47 5.91e-20 Birth weight; LIHC cis rs9640161 0.830 rs11768108 chr7:150064150 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -7.94 -0.39 2.84e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7116495 0.609 rs10501408 chr11:71680590 C/T cg10381502 chr11:71823885 C11orf51 -0.94 -7.88 -0.39 4.44e-14 Severe influenza A (H1N1) infection; LIHC cis rs3741151 0.764 rs79892955 chr11:73096280 G/T cg17517138 chr11:73019481 ARHGEF17 0.86 6.23 0.32 1.39e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg09417038 chr21:47716443 C21orf57 -0.48 -7.22 -0.36 3.41e-12 Testicular germ cell tumor; LIHC cis rs600806 0.778 rs11101961 chr1:110008813 T/C cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.8 -0.39 7.43e-14 Intelligence (multi-trait analysis); LIHC cis rs16866061 1.000 rs3768886 chr2:225450161 G/C cg12698349 chr2:225449008 CUL3 0.79 13.97 0.6 2.12e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs796364 0.589 rs6743217 chr2:201134914 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.53 -6.21 -0.32 1.52e-9 Schizophrenia; LIHC cis rs9733 0.569 rs11204691 chr1:150644339 A/T cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs11711311 1.000 rs9865965 chr3:113450495 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.05 -0.36 9.75e-12 IgG glycosylation; LIHC cis rs9325144 0.560 rs2387923 chr12:38662677 G/A cg26384229 chr12:38710491 ALG10B -0.48 -7.36 -0.37 1.38e-12 Morning vs. evening chronotype; LIHC cis rs864537 0.584 rs7523907 chr1:167427247 A/G cg22356347 chr1:167427500 CD247 -0.34 -6.19 -0.32 1.68e-9 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs769267 0.930 rs2301784 chr19:19390749 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC cis rs7116495 1.000 rs7103210 chr11:71648966 G/C cg26138937 chr11:71823887 C11orf51 -0.7 -6.99 -0.35 1.45e-11 Severe influenza A (H1N1) infection; LIHC cis rs9309473 1.000 rs6711033 chr2:73746643 T/C cg20560298 chr2:73613845 ALMS1 -0.55 -6.84 -0.35 3.66e-11 Metabolite levels; LIHC cis rs7772486 0.712 rs1292335 chr6:145967877 G/T cg23711669 chr6:146136114 FBXO30 0.53 9.38 0.45 9.28e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs1580019 0.563 rs34319173 chr7:32585904 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.11 0.44 6.89e-18 Cognitive ability; LIHC cis rs7584330 0.518 rs74478860 chr2:238437364 C/G cg08992911 chr2:238395768 MLPH 0.54 5.98 0.31 5.71e-9 Prostate cancer; LIHC cis rs858239 0.539 rs1358442 chr7:23189739 C/T cg23682824 chr7:23144976 KLHL7 0.46 6.96 0.35 1.71e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs1814175 0.791 rs10839395 chr11:49846274 G/T cg18944383 chr4:111397179 ENPEP 0.27 7.01 0.35 1.28e-11 Height; LIHC trans rs875971 0.965 rs9969301 chr7:65781655 G/A cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.2e-10 Aortic root size; LIHC cis rs9549367 0.789 rs3850451 chr13:113905812 C/G cg18105134 chr13:113819100 PROZ -0.68 -11.52 -0.53 3.56e-26 Platelet distribution width; LIHC cis rs11625487 0.609 rs17824567 chr14:77976450 G/T cg20045696 chr14:77926864 AHSA1 0.77 6.21 0.32 1.55e-9 Neutrophil percentage of white cells;Sum neutrophil eosinophil counts;Neutrophil count; LIHC cis rs1866706 0.865 rs61878772 chr11:12873769 C/G cg25843174 chr11:12811716 TEAD1 -0.29 -6.07 -0.31 3.33e-9 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.561 rs72783615 chr2:24296397 C/A cg06627628 chr2:24431161 ITSN2 -0.65 -7.48 -0.38 6.21e-13 Lymphocyte counts; LIHC cis rs208520 0.874 rs208470 chr6:66916402 G/A cg07460842 chr6:66804631 NA -0.7 -7.73 -0.39 1.22e-13 Exhaled nitric oxide output; LIHC trans rs1814175 0.817 rs2866863 chr11:49953242 C/T cg03929089 chr4:120376271 NA -0.89 -18.27 -0.7 1.61e-52 Height; LIHC cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg12373951 chr3:133503437 NA 0.51 8.37 0.41 1.53e-15 Iron status biomarkers; LIHC cis rs58688157 0.960 rs702966 chr11:611919 C/G cg01842473 chr11:617407 IRF7;MUPCDH -0.57 -6.31 -0.32 8.65e-10 Systemic lupus erythematosus; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18755078 chr14:31028811 G2E3 0.36 6.08 0.31 3.17e-9 Cognitive function; LIHC cis rs6960043 0.818 rs10228796 chr7:15064190 C/G cg19272540 chr7:15055459 NA -0.24 -6.54 -0.33 2.21e-10 Type 2 diabetes; LIHC cis rs1957429 0.808 rs6573580 chr14:65331766 C/G cg23373153 chr14:65346875 NA 0.79 11.28 0.52 2.77e-25 Pediatric areal bone mineral density (radius); LIHC cis rs9457247 0.602 rs10484530 chr6:167461562 C/T cg12798992 chr6:167411361 FGFR1OP 0.45 6.72 0.34 7.81e-11 Crohn's disease; LIHC cis rs10088262 0.629 rs12549683 chr8:124798276 G/C cg02993010 chr8:124780839 FAM91A1 -0.47 -6.06 -0.31 3.69e-9 Pancreatic cancer; LIHC cis rs7208859 0.623 rs7220999 chr17:29149298 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.12 0.4 8.57e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg25403416 chr19:30193069 C19orf12 0.32 6.11 0.31 2.69e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7927771 0.507 rs10838759 chr11:47785347 T/C cg20307385 chr11:47447363 PSMC3 0.72 10.68 0.5 3.75e-23 Subjective well-being; LIHC trans rs7448169 1.000 rs7705032 chr5:99147433 C/G cg11015893 chr7:135433540 FAM180A 0.25 6.14 0.32 2.33e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg17424134 chr2:27616206 FTHL3;PPM1G -0.42 -6.25 -0.32 1.26e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs798554 1.000 rs798540 chr7:2764130 G/A cg04166393 chr7:2884313 GNA12 0.43 5.9 0.3 8.69e-9 Height; LIHC cis rs10461617 0.541 rs7715822 chr5:56043600 G/T cg17801930 chr5:56009405 NA -0.59 -6.9 -0.35 2.59e-11 Type 2 diabetes; LIHC cis rs17286411 0.750 rs4788561 chr16:71878255 G/A cg03805757 chr16:71968109 PKD1L3 0.44 6.24 0.32 1.26e-9 Blood protein levels; LIHC cis rs7945718 0.967 rs7931147 chr11:12748884 C/A cg25843174 chr11:12811716 TEAD1 0.35 7.88 0.39 4.41e-14 Educational attainment (years of education); LIHC cis rs896854 0.654 rs896847 chr8:95972551 G/A cg16049864 chr8:95962084 TP53INP1 -0.6 -11.49 -0.53 4.52e-26 Type 2 diabetes; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg24947258 chr10:43904864 HNRNPF -0.51 -6.06 -0.31 3.53e-9 Facial morphology (factor 20); LIHC cis rs3784262 0.934 rs7164408 chr15:58259336 A/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.37 -0.33 6.11e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs11764590 0.694 rs7797112 chr7:2085165 T/C cg23422044 chr7:1970798 MAD1L1 -0.5 -7.88 -0.39 4.53e-14 Neuroticism; LIHC cis rs9303401 0.659 rs17822908 chr17:56801778 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC cis rs12908161 1.000 rs62019464 chr15:85294469 T/A cg17507749 chr15:85114479 UBE2QP1 0.62 7.09 0.36 7.9e-12 Schizophrenia; LIHC cis rs7666738 0.822 rs28367231 chr4:98845726 G/T cg05340658 chr4:99064831 C4orf37 0.65 11.71 0.54 7.1e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7618501 0.521 rs3733134 chr3:49939503 C/T cg05623727 chr3:50126028 RBM5 0.35 5.89 0.3 9.08e-9 Intelligence (multi-trait analysis); LIHC cis rs4917300 0.626 rs902821 chr8:143100074 G/A cg25363559 chr8:143086065 NA -0.28 -8.34 -0.41 1.8e-15 Amyotrophic lateral sclerosis; LIHC trans rs783540 1.000 rs1267657 chr15:83215251 T/C cg18393722 chr15:85113863 UBE2QP1 -0.43 -7.46 -0.37 6.98e-13 Schizophrenia; LIHC cis rs4555082 0.957 rs2816608 chr14:105718407 A/G cg13114125 chr14:105738426 BRF1 0.65 8.69 0.43 1.53e-16 Mean platelet volume;Platelet distribution width; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18035571 chr5:176580675 NSD1 -0.28 -6.51 -0.33 2.63e-10 Calcium levels; LIHC cis rs6942756 0.712 rs6467241 chr7:128997838 A/G cg02491457 chr7:128862824 NA -0.56 -8.53 -0.42 4.73e-16 White matter hyperintensity burden; LIHC cis rs4481887 0.512 rs1538702 chr1:248519665 A/G cg12085619 chr1:248636455 OR2T3 0.33 6.29 0.32 9.77e-10 Common traits (Other); LIHC cis rs7927592 0.913 rs66752716 chr11:68273626 C/T cg20283391 chr11:68216788 NA -0.52 -7.75 -0.39 1.05e-13 Total body bone mineral density; LIHC cis rs11696845 0.776 rs6073538 chr20:43379264 A/C cg25301532 chr20:43378953 KCNK15 0.26 6.18 0.32 1.8e-9 Obesity-related traits; LIHC cis rs5769707 0.967 rs2187891 chr22:49994094 C/T cg07959070 chr22:50026188 C22orf34 -0.28 -6.92 -0.35 2.29e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg03354898 chr7:1950403 MAD1L1 -0.37 -5.74 -0.3 2.07e-8 Bipolar disorder and schizophrenia; LIHC cis rs2637030 0.515 rs381374 chr5:52927813 A/G cg06476337 chr5:52856530 NDUFS4 0.43 6.83 0.35 3.88e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs7149337 1.000 rs8006432 chr14:51731306 A/T cg23942311 chr14:51606299 NA 0.32 6.25 0.32 1.23e-9 Cancer; LIHC cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg17554472 chr22:41940697 POLR3H 0.56 6.01 0.31 4.84e-9 Vitiligo; LIHC cis rs1577917 1.000 rs34581302 chr6:86705948 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.81 -0.47 3.63e-20 Response to antipsychotic treatment; LIHC cis rs6582630 0.502 rs11504451 chr12:38425294 G/A cg26384229 chr12:38710491 ALG10B 0.6 8.44 0.42 8.89e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs7589728 0.748 rs3791357 chr2:88478664 C/T cg04511125 chr2:88470314 THNSL2 0.9 8.95 0.44 2.25e-17 Plasma clusterin levels; LIHC cis rs9486719 1.000 rs2092096 chr6:96870919 A/G cg06623918 chr6:96969491 KIAA0776 0.76 7.47 0.37 6.92e-13 Migraine;Coronary artery disease; LIHC cis rs7249142 0.526 rs7256811 chr19:19283551 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.27 -0.32 1.11e-9 IgG glycosylation; LIHC cis rs2635047 0.967 rs2668786 chr18:44708472 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.48 6.65 0.34 1.13e-10 Educational attainment; LIHC cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg06481639 chr22:41940642 POLR3H -0.71 -7.18 -0.36 4.25e-12 Vitiligo; LIHC cis rs7223966 1.000 rs2874121 chr17:61731024 C/T cg05941027 chr17:61774174 LIMD2 0.34 6.9 0.35 2.47e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6066825 0.546 rs2598 chr20:47241618 A/G cg18078177 chr20:47281410 PREX1 0.47 7.76 0.39 9.74e-14 Colorectal cancer; LIHC cis rs9818758 0.607 rs67831908 chr3:49313513 T/G cg00383909 chr3:49044727 WDR6 0.77 6.32 0.32 8.14e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11098499 0.863 rs1552095 chr4:120460306 A/G cg09307838 chr4:120376055 NA 0.72 10.69 0.5 3.41e-23 Corneal astigmatism; LIHC cis rs2067615 0.524 rs10861646 chr12:107071182 C/T cg15890332 chr12:107067104 RFX4 0.27 6.43 0.33 4.34e-10 Heart rate; LIHC cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg06697600 chr4:7070879 GRPEL1 0.66 10.86 0.51 8.12e-24 Monocyte percentage of white cells; LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg23601095 chr6:26197514 HIST1H3D 0.55 5.83 0.3 1.27e-8 Gout;Renal underexcretion gout; LIHC cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg16145915 chr7:1198662 ZFAND2A -0.32 -7.77 -0.39 9.44e-14 Longevity;Endometriosis; LIHC cis rs1577917 0.771 rs7762321 chr6:86412146 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.49 9.71 0.46 7.5e-20 Response to antipsychotic treatment; LIHC trans rs4710654 0.516 rs6914109 chr6:68509394 A/G cg00011122 chr16:11439027 C16orf75 -0.4 -6.05 -0.31 3.78e-9 Response to amphetamines; LIHC cis rs2070433 1.000 rs2839306 chr21:47954219 G/T cg12379764 chr21:47803548 PCNT -0.6 -8.71 -0.43 1.35e-16 Lymphocyte counts; LIHC cis rs2404602 0.692 rs58973160 chr15:77000342 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.86 0.3 1.09e-8 Blood metabolite levels; LIHC cis rs7927592 0.731 rs2156463 chr11:68386311 T/C cg01657329 chr11:68192670 LRP5 -0.53 -7.7 -0.38 1.51e-13 Total body bone mineral density; LIHC cis rs6952808 0.531 rs73039217 chr7:2178731 G/A cg21782813 chr7:2030301 MAD1L1 0.37 6.32 0.32 8.29e-10 Bipolar disorder and schizophrenia; LIHC cis rs807029 0.577 rs3740488 chr10:102754033 A/T cg27255678 chr10:102756921 LZTS2 0.51 7.28 0.37 2.37e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs3744061 0.569 rs2240769 chr17:74718155 C/T cg13533061 chr17:74712429 JMJD6 -0.32 -5.74 -0.3 2.04e-8 Retinal arteriolar caliber; LIHC trans rs7193541 0.682 rs28681530 chr16:74682496 C/T cg23598604 chr1:99732472 LPPR4 -0.29 -6.21 -0.32 1.5e-9 Multiple myeloma; LIHC cis rs1670533 1.000 rs1670533 chr4:1078187 G/A cg27284194 chr4:1044797 NA 0.6 8.94 0.44 2.57e-17 Recombination rate (females); LIHC cis rs7614311 0.681 rs10510903 chr3:63970192 C/G cg22134162 chr3:63841271 THOC7 -0.51 -5.78 -0.3 1.71e-8 Lung function (FVC);Lung function (FEV1); LIHC cis rs8016982 0.633 rs8019108 chr14:81716781 A/T cg01989461 chr14:81687754 GTF2A1 0.7 14.06 0.61 9.79e-36 Schizophrenia; LIHC trans rs2727020 0.595 rs10839286 chr11:49497063 C/A cg15704280 chr7:45808275 SEPT13 -1.0 -22.08 -0.77 8.55e-68 Coronary artery disease; LIHC trans rs867371 1.000 rs881308 chr15:82475797 A/G cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.75 -0.34 6.31e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs709400 0.663 rs11628213 chr14:103952453 A/C cg26031613 chr14:104095156 KLC1 0.75 9.28 0.45 1.99e-18 Body mass index; LIHC trans rs11098499 0.955 rs1511019 chr4:120166007 T/G cg25214090 chr10:38739885 LOC399744 0.51 7.77 0.39 9.47e-14 Corneal astigmatism; LIHC cis rs7772486 0.686 rs857883 chr6:145969214 G/T cg23711669 chr6:146136114 FBXO30 -0.7 -12.65 -0.56 2.45e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 1.000 rs58680688 chr1:67443751 C/G cg02640540 chr1:67518911 SLC35D1 -0.42 -5.8 -0.3 1.51e-8 Lymphocyte percentage of white cells; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg07677032 chr17:61819896 STRADA 0.44 6.44 0.33 4.01e-10 Prudent dietary pattern; LIHC cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg00684032 chr4:1343700 KIAA1530 0.35 5.78 0.3 1.72e-8 Obesity-related traits; LIHC cis rs11676348 0.783 rs4674252 chr2:218984478 G/A cg00012203 chr2:219082015 ARPC2 -0.55 -7.69 -0.38 1.53e-13 Ulcerative colitis; LIHC cis rs4788815 0.691 rs4788808 chr16:71615613 A/G cg06353428 chr16:71660113 MARVELD3 -0.43 -6.61 -0.34 1.49e-10 Metabolite levels; LIHC cis rs9359856 0.673 rs1179897 chr6:90318624 T/C cg13799429 chr6:90582589 CASP8AP2 -0.62 -6.44 -0.33 4.04e-10 Bipolar disorder; LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg11062466 chr8:58055876 NA 0.53 7.55 0.38 3.96e-13 Developmental language disorder (linguistic errors); LIHC cis rs4908768 0.906 rs12117910 chr1:8556953 A/C cg20416874 chr1:8611966 RERE 0.57 8.8 0.43 6.93e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs61990749 0.511 rs10146144 chr14:78325300 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.5 7.9 0.39 3.95e-14 Fibroblast growth factor basic levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06862150 chr5:151150984 G3BP1 0.44 6.07 0.31 3.42e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.5 -6.26 -0.32 1.12e-9 Diastolic blood pressure; LIHC cis rs12079745 0.793 rs113298876 chr1:169280579 C/A cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 1.94e-11 QT interval; LIHC cis rs9682041 1.000 rs6444920 chr3:170090374 A/G cg11886554 chr3:170076028 SKIL 0.75 6.33 0.32 7.78e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs7584330 0.554 rs13390883 chr2:238432619 A/T cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.42e-9 Prostate cancer; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs28530618 0.603 rs13043743 chr20:31257083 C/T cg13636640 chr20:31349939 DNMT3B -0.42 -5.84 -0.3 1.2e-8 Birth weight; LIHC trans rs1005277 0.505 rs7099777 chr10:38183569 A/C cg17830980 chr10:43048298 ZNF37B 0.46 8.97 0.44 2.03e-17 Extrinsic epigenetic age acceleration; LIHC cis rs7095944 0.614 rs10901817 chr10:126443404 A/T cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.87e-10 Asthma; LIHC cis rs6701037 0.566 rs10753091 chr1:175134571 T/C cg00321850 chr1:175162397 KIAA0040 0.46 7.6 0.38 2.88e-13 Alcohol dependence; LIHC cis rs17376456 0.877 rs10476598 chr5:93367281 C/T cg25358565 chr5:93447407 FAM172A -1.08 -10.13 -0.48 2.9e-21 Diabetic retinopathy; LIHC cis rs12220238 0.915 rs1908334 chr10:75991721 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.76 0.34 5.8e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs801193 0.591 rs4506088 chr7:66135457 G/A cg18876405 chr7:65276391 NA -0.32 -5.91 -0.3 8.39e-9 Aortic root size; LIHC cis rs2075371 1.000 rs2058976 chr7:133981379 G/T cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.74e-14 Mean platelet volume; LIHC cis rs6424115 0.830 rs6680132 chr1:24198804 T/C cg15997130 chr1:24165203 NA 0.37 7.39 0.37 1.1e-12 Immature fraction of reticulocytes; LIHC cis rs9902453 0.765 rs2169810 chr17:28167941 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 13.68 0.59 2.69e-34 Coffee consumption (cups per day); LIHC cis rs709400 0.965 rs861534 chr14:104168701 C/T cg26031613 chr14:104095156 KLC1 0.99 12.53 0.56 6.56e-30 Body mass index; LIHC cis rs4407350 0.933 rs5765732 chr22:44922761 A/G cg26276947 chr22:44892394 LDOC1L 0.34 6.33 0.32 7.71e-10 Intelligence (multi-trait analysis); LIHC cis rs6752107 0.967 rs11694081 chr2:234148586 A/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.47 7.0 0.35 1.33e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4474465 0.920 rs7944485 chr11:78225261 T/C cg27205649 chr11:78285834 NARS2 0.4 6.0 0.31 5.1e-9 Alzheimer's disease (survival time); LIHC cis rs929354 0.772 rs7778193 chr7:156980087 C/T cg05182265 chr7:156933206 UBE3C -0.31 -5.71 -0.3 2.44e-8 Body mass index; LIHC cis rs17826219 0.706 rs8075357 chr17:29057197 A/C cg13385521 chr17:29058706 SUZ12P 0.84 8.43 0.41 1e-15 Body mass index; LIHC cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg18252515 chr7:66147081 NA -1.3 -16.9 -0.67 5.23e-47 Diabetic kidney disease; LIHC cis rs8084351 0.577 rs35840237 chr18:50607475 T/A cg24270629 chr18:50823537 DCC 0.44 6.59 0.34 1.69e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs12980942 1.000 rs7257310 chr19:41827120 C/T cg25627403 chr19:41769009 HNRNPUL1 0.48 5.95 0.31 6.73e-9 Coronary artery disease; LIHC cis rs2228479 0.702 rs12600151 chr16:89831558 C/T cg06558623 chr16:89946397 TCF25 0.85 11.71 0.53 7.62e-27 Skin colour saturation; LIHC cis rs79387448 0.564 rs77375846 chr2:103155075 T/C cg09003973 chr2:102972529 NA 1.05 7.58 0.38 3.32e-13 Gut microbiota (bacterial taxa); LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg20102877 chr2:27665638 KRTCAP3 -0.44 -6.04 -0.31 4.08e-9 Total body bone mineral density; LIHC cis rs10493773 0.649 rs17398321 chr1:86084493 A/G cg17807903 chr1:86174739 ZNHIT6 -0.5 -7.17 -0.36 4.6e-12 Urate levels in overweight individuals; LIHC cis rs7617773 0.780 rs11716848 chr3:48378500 G/A cg11946769 chr3:48343235 NME6 0.93 11.81 0.54 3.03e-27 Coronary artery disease; LIHC cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg09323728 chr8:95962352 TP53INP1 -0.32 -7.2 -0.36 3.84e-12 Type 2 diabetes; LIHC cis rs1018836 0.828 rs9297870 chr8:91570691 C/G cg16814680 chr8:91681699 NA -0.55 -8.63 -0.42 2.27e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs919433 0.617 rs2037590 chr2:198584775 T/A cg00792783 chr2:198669748 PLCL1 -0.43 -6.24 -0.32 1.27e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs35306767 0.855 rs35666723 chr10:867346 A/G cg26597838 chr10:835615 NA 1.5 16.55 0.67 1.29e-45 Eosinophil percentage of granulocytes; LIHC cis rs9420 0.528 rs34052104 chr11:57384519 A/C cg19752551 chr11:57585705 CTNND1 -0.46 -5.98 -0.31 5.62e-9 Schizophrenia; LIHC cis rs16866061 1.000 rs72974238 chr2:225432470 C/A cg12698349 chr2:225449008 CUL3 0.8 13.99 0.6 1.81e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs7208859 0.623 rs8067338 chr17:29102345 T/C cg13385521 chr17:29058706 SUZ12P 0.84 8.27 0.41 3.06e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6430585 0.697 rs1050115 chr2:136511817 A/G cg07169764 chr2:136633963 MCM6 1.15 16.2 0.66 3.44e-44 Corneal structure; LIHC cis rs6570726 0.935 rs419850 chr6:145827281 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6424115 0.830 rs2503002 chr1:24196957 C/G cg15997130 chr1:24165203 NA 0.38 7.88 0.39 4.51e-14 Immature fraction of reticulocytes; LIHC cis rs7937682 1.000 rs7128353 chr11:111538875 A/G cg09085632 chr11:111637200 PPP2R1B -1.02 -12.94 -0.57 1.87e-31 Primary sclerosing cholangitis; LIHC cis rs4727027 0.716 rs4727020 chr7:148837317 C/T cg23583168 chr7:148888333 NA -0.72 -9.43 -0.45 6.54e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6963495 0.546 rs2697020 chr7:105150046 C/T cg19920283 chr7:105172520 RINT1 0.48 6.13 0.31 2.49e-9 Bipolar disorder (body mass index interaction); LIHC cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg06634786 chr22:41940651 POLR3H 0.73 7.59 0.38 3.16e-13 Vitiligo; LIHC cis rs7267979 1.000 rs2257809 chr20:25266476 C/T cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2304069 0.644 rs216131 chr5:149431223 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.85 10.78 0.5 1.66e-23 HIV-1 control; LIHC cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg03264133 chr6:25882463 NA 0.57 7.67 0.38 1.76e-13 Blood metabolite levels; LIHC cis rs11690935 0.885 rs6727017 chr2:172766847 T/A cg13550731 chr2:172543902 DYNC1I2 -0.8 -14.42 -0.61 3.6e-37 Schizophrenia; LIHC trans rs208520 1.000 rs9453671 chr6:66991208 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.95 0.35 1.83e-11 Exhaled nitric oxide output; LIHC cis rs17376456 0.778 rs10440717 chr5:93424852 C/A cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs10751667 0.577 rs7946461 chr11:974035 A/G cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.53e-13 Alzheimer's disease (late onset); LIHC cis rs1865721 0.804 rs7243462 chr18:73147998 A/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.85 -0.39 5.35e-14 Intelligence; LIHC cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg11062466 chr8:58055876 NA 0.4 5.87 0.3 1.03e-8 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg08219700 chr8:58056026 NA 0.55 6.74 0.34 6.72e-11 Developmental language disorder (linguistic errors); LIHC cis rs7918232 0.830 rs7911024 chr10:27433636 A/C cg14442939 chr10:27389572 ANKRD26 0.72 7.02 0.36 1.16e-11 Breast cancer; LIHC cis rs1816752 0.870 rs9581027 chr13:24997928 G/A cg02811702 chr13:24901961 NA 0.23 5.76 0.3 1.89e-8 Obesity-related traits; LIHC cis rs1062177 1.000 rs2964571 chr5:151171256 C/T cg00977110 chr5:151150581 G3BP1 0.55 6.98 0.35 1.56e-11 Preschool internalizing problems; LIHC cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg03396347 chr1:1875803 NA -0.44 -8.04 -0.4 1.45e-14 Body mass index; LIHC trans rs2243480 1.000 rs458291 chr7:65520479 C/A cg10756647 chr7:56101905 PSPH 1.08 13.33 0.58 6.29e-33 Diabetic kidney disease; LIHC cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg11663144 chr21:46675770 NA -0.37 -6.78 -0.34 5.4e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2637030 0.559 rs376566 chr5:53005420 G/A cg06476337 chr5:52856530 NDUFS4 0.42 6.69 0.34 8.96e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs12594515 0.967 rs71405295 chr15:45988921 T/C cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.84e-19 Waist circumference;Weight; LIHC cis rs10463316 0.894 rs7712569 chr5:150766089 A/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.04e-10 Metabolite levels (Pyroglutamine); LIHC cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC cis rs7131987 0.903 rs6487796 chr12:29422764 A/G cg21522988 chr12:29376872 FAR2 0.28 6.41 0.33 4.84e-10 QT interval; LIHC cis rs2230307 0.536 rs56215716 chr1:100447486 G/A cg24955406 chr1:100503596 HIAT1 0.59 5.94 0.31 7.19e-9 Carotid intima media thickness; LIHC cis rs7772486 0.875 rs9322044 chr6:146369608 T/C cg23711669 chr6:146136114 FBXO30 0.67 12.09 0.55 2.96e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs1577917 0.771 rs2842602 chr6:86331887 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.92 -0.39 3.27e-14 Response to antipsychotic treatment; LIHC cis rs7100689 0.646 rs7899791 chr10:82091950 A/T cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs3749237 0.595 rs7637999 chr3:49535115 C/T cg06212747 chr3:49208901 KLHDC8B 0.46 6.01 0.31 4.66e-9 Resting heart rate; LIHC trans rs208520 0.690 rs12202805 chr6:66703903 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.73 -8.43 -0.41 9.52e-16 Exhaled nitric oxide output; LIHC cis rs7582720 1.000 rs72936852 chr2:203775475 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.39 -0.37 1.17e-12 Lymphocyte counts; LIHC cis rs17270561 0.609 rs7772382 chr6:25708116 C/T cg17691542 chr6:26056736 HIST1H1C 0.44 5.86 0.3 1.09e-8 Iron status biomarkers; LIHC cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg04944784 chr2:26401820 FAM59B 0.71 9.39 0.45 8.96e-19 Gut microbiome composition (summer); LIHC cis rs2933343 1.000 rs2929859 chr3:128608341 T/G cg25356066 chr3:128598488 ACAD9 0.54 7.21 0.36 3.73e-12 IgG glycosylation; LIHC cis rs7100689 0.598 rs2342815 chr10:82086532 T/C cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs4919087 0.748 rs701819 chr10:98986316 C/A cg25902810 chr10:99078978 FRAT1 -0.56 -6.49 -0.33 3.07e-10 Monocyte count; LIHC cis rs6815814 0.950 rs5743571 chr4:38805489 C/T cg06935464 chr4:38784597 TLR10 0.48 7.38 0.37 1.23e-12 Breast cancer; LIHC trans rs1814175 0.645 rs7103554 chr11:50027612 G/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg00280220 chr17:61926910 NA 0.43 7.06 0.36 9.37e-12 Prudent dietary pattern; LIHC cis rs72781680 0.566 rs72796106 chr2:23901362 A/C cg08917208 chr2:24149416 ATAD2B 0.69 6.4 0.33 5.03e-10 Lymphocyte counts; LIHC cis rs7208859 0.673 rs9889755 chr17:29234505 A/G cg14067834 chr17:29058358 SUZ12P -0.62 -6.47 -0.33 3.45e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11955398 0.665 rs11948543 chr5:59918937 T/C cg02684056 chr5:59996105 DEPDC1B 0.41 6.09 0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.894 rs10496092 chr2:61524679 C/T cg14146966 chr2:61757674 XPO1 -0.43 -7.33 -0.37 1.71e-12 Tuberculosis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07810114 chr1:12018622 PLOD1 0.54 8.2 0.41 4.8e-15 Longevity; LIHC cis rs2273669 0.667 rs12212402 chr6:109306681 T/C cg05315195 chr6:109294784 ARMC2 -0.52 -5.76 -0.3 1.85e-8 Prostate cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06329143 chr18:48556512 SMAD4 -0.49 -6.43 -0.33 4.18e-10 Systolic blood pressure; LIHC cis rs3820068 0.581 rs16851841 chr1:15922713 A/G cg17385448 chr1:15911702 AGMAT 0.35 6.15 0.32 2.21e-9 Systolic blood pressure; LIHC cis rs9486719 0.948 rs2499817 chr6:96878321 C/T cg06623918 chr6:96969491 KIAA0776 0.73 7.18 0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs9309711 0.643 rs4264589 chr2:3481098 G/T cg15506890 chr2:3487001 NA -0.48 -7.73 -0.39 1.18e-13 Neurofibrillary tangles; LIHC cis rs918629 0.530 rs3777203 chr5:95234377 C/T cg10483112 chr5:95245456 ELL2 -0.36 -6.59 -0.34 1.67e-10 IgG glycosylation; LIHC cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg22907277 chr7:1156413 C7orf50 0.43 6.22 0.32 1.45e-9 Longevity;Endometriosis; LIHC cis rs2842992 0.747 rs1547093 chr6:160205991 C/A cg19482086 chr6:160211437 TCP1;MRPL18 0.68 12.12 0.55 2.25e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs9916302 0.851 rs12936996 chr17:37665554 A/G cg07936489 chr17:37558343 FBXL20 0.84 13.56 0.59 8.25e-34 Glomerular filtration rate (creatinine); LIHC cis rs12086130 0.892 rs3176466 chr1:51438365 A/G cg07174182 chr1:51127561 FAF1 0.72 8.34 0.41 1.84e-15 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs2637266 0.935 rs2583052 chr10:78403288 C/G cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs6960043 1.000 rs6972516 chr7:15051789 G/T cg19272540 chr7:15055459 NA -0.22 -6.26 -0.32 1.12e-9 Type 2 diabetes; LIHC cis rs79839061 0.610 rs11731387 chr4:851357 C/T cg07828340 chr4:882639 GAK 0.81 6.72 0.34 7.8e-11 Intelligence (multi-trait analysis); LIHC cis rs897984 0.806 rs12924903 chr16:30928970 C/T cg02466173 chr16:30829666 NA -0.41 -6.73 -0.34 7.22e-11 Dementia with Lewy bodies; LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.73 13.65 0.59 3.58e-34 Prudent dietary pattern; LIHC cis rs2732480 0.557 rs2634682 chr12:48732943 T/C cg21466736 chr12:48725269 NA -0.73 -11.26 -0.52 3.02e-25 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs7246657 0.943 rs10420754 chr19:37959372 C/G cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs1401999 0.966 rs2313212 chr3:183700928 A/G cg05044414 chr3:183734942 ABCC5 0.33 5.88 0.3 9.51e-9 Anterior chamber depth; LIHC cis rs35306767 0.761 rs11253559 chr10:1044809 T/C cg20503657 chr10:835505 NA 0.82 7.72 0.39 1.3e-13 Eosinophil percentage of granulocytes; LIHC cis rs7429990 0.932 rs11720151 chr3:48140634 G/A cg11946769 chr3:48343235 NME6 -0.47 -6.24 -0.32 1.27e-9 Educational attainment (years of education); LIHC cis rs600806 0.713 rs10745305 chr1:110012148 A/G cg16275483 chr1:110013120 SYPL2 -0.49 -6.08 -0.31 3.2e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg09455208 chr3:40491958 NA 0.42 8.46 0.42 7.64e-16 Renal cell carcinoma; LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg04267008 chr7:1944627 MAD1L1 -0.6 -9.21 -0.45 3.26e-18 Bipolar disorder and schizophrenia; LIHC cis rs5769765 0.624 rs2285187 chr22:50185432 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.53 -6.36 -0.33 6.6e-10 Schizophrenia; LIHC cis rs796364 1.000 rs281774 chr2:200814572 C/T cg23649088 chr2:200775458 C2orf69 0.5 6.23 0.32 1.37e-9 Schizophrenia; LIHC cis rs16958440 1.000 rs62096464 chr18:44629207 T/A cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC cis rs12477438 0.501 rs34272114 chr2:99737443 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs1008375 1.000 rs28693609 chr4:17645233 C/T cg02297831 chr4:17616191 MED28 0.49 7.57 0.38 3.47e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1499614 1.000 rs2659913 chr7:66157336 T/A cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC cis rs12980942 1.000 rs6957 chr19:41830606 T/C cg25627403 chr19:41769009 HNRNPUL1 0.48 5.97 0.31 6.08e-9 Coronary artery disease; LIHC cis rs4820294 0.516 rs12484441 chr22:38097359 C/G cg10587741 chr22:38071170 LGALS1 0.68 9.4 0.45 8.19e-19 Fat distribution (HIV); LIHC cis rs6430585 0.528 rs614193 chr2:136653925 A/T cg07169764 chr2:136633963 MCM6 0.99 15.16 0.63 4.38e-40 Corneal structure; LIHC cis rs7523273 1.000 rs12123251 chr1:207992546 G/A cg22525895 chr1:207977042 MIR29B2 -0.69 -10.45 -0.49 2.26e-22 Schizophrenia; LIHC cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg08280861 chr8:58055591 NA 0.52 6.04 0.31 3.92e-9 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.659 rs12940212 chr17:56674474 T/C cg25039879 chr17:56429692 SUPT4H1 0.84 9.58 0.46 1.99e-19 Cognitive test performance; LIHC cis rs1401999 0.807 rs9869029 chr3:183735286 C/G cg05044414 chr3:183734942 ABCC5 0.34 5.87 0.3 1.04e-8 Anterior chamber depth; LIHC cis rs11122272 0.735 rs2250704 chr1:231486647 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.98 -0.51 3.16e-24 Hemoglobin concentration; LIHC cis rs4474465 0.850 rs10899539 chr11:78243743 T/C cg27205649 chr11:78285834 NARS2 0.39 6.15 0.32 2.14e-9 Alzheimer's disease (survival time); LIHC trans rs7246657 0.943 rs10405407 chr19:37839164 C/T cg24637308 chr11:6592297 DNHD1 0.43 6.09 0.31 2.99e-9 Coronary artery calcification; LIHC cis rs801193 0.935 rs2659916 chr7:66151352 C/G cg14393609 chr7:65229607 NA 0.38 5.87 0.3 1.02e-8 Aortic root size; LIHC cis rs1873147 0.569 rs12593531 chr15:63309936 C/G cg12160578 chr15:63334699 TPM1 0.69 9.02 0.44 1.34e-17 Orofacial clefts; LIHC cis rs7945718 0.934 rs4553350 chr11:12759834 A/G cg25843174 chr11:12811716 TEAD1 -0.28 -6.39 -0.33 5.35e-10 Educational attainment (years of education); LIHC cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC cis rs9916302 0.861 rs8081033 chr17:37506650 A/G cg07936489 chr17:37558343 FBXL20 0.84 13.6 0.59 5.67e-34 Glomerular filtration rate (creatinine); LIHC cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg07424592 chr7:64974309 NA 0.83 9.56 0.46 2.47e-19 Diabetic kidney disease; LIHC trans rs1814175 0.645 rs4598671 chr11:50003191 C/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs36051895 0.664 rs3780381 chr9:5114523 A/C cg02405213 chr9:5042618 JAK2 -0.64 -10.74 -0.5 2.3e-23 Pediatric autoimmune diseases; LIHC cis rs17685 0.712 rs6954569 chr7:75738885 T/A cg16684958 chr7:75615977 POR 0.51 8.59 0.42 3.18e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg18306943 chr3:40428807 ENTPD3 -0.36 -6.45 -0.33 3.87e-10 Renal cell carcinoma; LIHC cis rs8081395 0.741 rs180532 chr17:58003297 A/G cg02344993 chr17:57696989 CLTC 0.35 5.71 0.3 2.44e-8 White blood cell count; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg05484376 chr2:27715224 FNDC4 0.38 6.46 0.33 3.57e-10 Total body bone mineral density; LIHC cis rs10791097 0.694 rs11222370 chr11:130744767 T/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs13392177 0.684 rs11682371 chr2:219079513 G/A cg00012203 chr2:219082015 ARPC2 -0.75 -11.33 -0.52 1.8e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs8060686 0.641 rs79577483 chr16:68036939 A/G cg05110241 chr16:68378359 PRMT7 -0.57 -6.75 -0.34 6.36e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs709400 0.663 rs72708893 chr14:103929535 G/A cg26031613 chr14:104095156 KLC1 0.75 9.68 0.46 9.64e-20 Body mass index; LIHC cis rs7223966 1.000 rs9747164 chr17:61864787 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 6.84 0.35 3.55e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1801251 1.000 rs778166 chr2:233664097 A/T cg25237894 chr2:233734115 C2orf82 0.59 11.62 0.53 1.59e-26 Coronary artery disease; LIHC cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg06873352 chr17:61820015 STRADA 0.72 12.5 0.56 9.04e-30 Prudent dietary pattern; LIHC cis rs8103278 0.864 rs2070737 chr19:46282890 A/T cg11657440 chr19:46296263 DMWD -0.53 -8.48 -0.42 6.68e-16 Coronary artery disease; LIHC cis rs8180040 0.966 rs922957 chr3:47422152 G/C cg16586182 chr3:47516702 SCAP 0.6 11.55 0.53 2.77e-26 Colorectal cancer; LIHC cis rs2439831 0.867 rs76542740 chr15:43891512 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.68 9.59 0.46 1.91e-19 Lung cancer in ever smokers; LIHC cis rs9768139 0.708 rs6459858 chr7:158115055 A/G cg25566285 chr7:158114605 PTPRN2 0.23 6.15 0.32 2.11e-9 Calcium levels; LIHC cis rs7075426 0.669 rs4934211 chr10:88203735 C/T cg07322936 chr10:88137208 NA 0.49 6.36 0.33 6.63e-10 Migraine without aura; LIHC cis rs8060686 0.545 rs12444313 chr16:68254404 A/C cg09835421 chr16:68378352 PRMT7 -0.52 -5.98 -0.31 5.58e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs9303401 0.659 rs8074016 chr17:56840587 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.24 0.55 7.83e-29 Cognitive test performance; LIHC cis rs9359856 0.636 rs4706345 chr6:90301565 C/T cg13799429 chr6:90582589 CASP8AP2 -0.62 -6.96 -0.35 1.72e-11 Bipolar disorder; LIHC cis rs1018836 0.923 rs4735230 chr8:91574184 G/C cg16814680 chr8:91681699 NA -0.61 -9.61 -0.46 1.67e-19 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2120019 0.938 rs8036573 chr15:75308690 C/T cg17294928 chr15:75287854 SCAMP5 -0.49 -7.26 -0.37 2.63e-12 Blood trace element (Zn levels); LIHC cis rs929354 0.553 rs34498858 chr7:156931337 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.83 -0.3 1.25e-8 Body mass index; LIHC cis rs2075371 1.000 rs447266 chr7:133989543 A/G cg20476274 chr7:133979776 SLC35B4 0.73 12.24 0.55 8.44e-29 Mean platelet volume; LIHC cis rs546131 0.928 rs552171 chr11:34830709 G/T cg06937548 chr11:34938143 PDHX;APIP 0.6 7.86 0.39 4.91e-14 Lung disease severity in cystic fibrosis; LIHC cis rs3768617 0.510 rs10458355 chr1:183063993 C/T ch.1.3577855R chr1:183094577 LAMC1 0.63 10.92 0.51 5.31e-24 Fuchs's corneal dystrophy; LIHC cis rs7618501 0.602 rs2526754 chr3:50125996 G/A cg24110177 chr3:50126178 RBM5 0.53 8.66 0.42 1.91e-16 Intelligence (multi-trait analysis); LIHC cis rs1559088 0.948 rs7259333 chr19:33579128 T/C cg17764715 chr19:33622953 WDR88 0.47 6.84 0.35 3.62e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs10493773 0.532 rs12064199 chr1:86187073 A/T cg17807903 chr1:86174739 ZNHIT6 -0.59 -11.71 -0.53 7.4e-27 Urate levels in overweight individuals; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13886124 chr9:130186480 ZNF79 0.48 6.43 0.33 4.42e-10 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs6502050 0.835 rs35555954 chr17:80122438 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs9420 0.961 rs11607056 chr11:57496820 C/T cg19752551 chr11:57585705 CTNND1 -0.53 -7.39 -0.37 1.16e-12 Schizophrenia; LIHC cis rs6502050 0.698 rs67143649 chr17:80117772 C/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg20887711 chr4:1340912 KIAA1530 0.46 7.02 0.35 1.21e-11 Obesity-related traits; LIHC cis rs12464559 0.649 rs4664066 chr2:152632406 T/C cg01189475 chr2:152685088 ARL5A 0.63 7.43 0.37 8.56e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7208859 0.524 rs8065744 chr17:29099449 C/T cg14067834 chr17:29058358 SUZ12P 0.71 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1443512 0.812 rs1992563 chr12:54330441 G/T cg25024717 chr12:54324583 NA -0.32 -6.3 -0.32 8.9e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs2594714 0.538 rs895819 chr19:13947292 A/G cg18576835 chr19:13944261 NA -0.47 -9.72 -0.47 6.84e-20 Breast cancer; LIHC cis rs7940866 0.770 rs10791104 chr11:130814893 A/T cg12179176 chr11:130786555 SNX19 0.64 9.38 0.45 9.2e-19 Schizophrenia; LIHC cis rs12220238 1.000 rs11000887 chr10:75897542 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.71 7.15 0.36 5.23e-12 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg20284218 chr11:62648405 SLC3A2 -0.54 -6.72 -0.34 7.76e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg10096929 chr1:156261403 TMEM79 0.4 6.63 0.34 1.28e-10 Tonsillectomy; LIHC cis rs2997447 0.846 rs61775427 chr1:26408768 G/A cg19633962 chr1:26362018 EXTL1 -0.69 -6.32 -0.32 8.04e-10 QRS complex (12-leadsum); LIHC cis rs12188164 0.543 rs890972 chr5:462465 C/A cg00049323 chr5:472564 LOC25845 0.35 5.85 0.3 1.14e-8 Cystic fibrosis severity; LIHC trans rs526631 0.564 rs10896051 chr11:65578759 C/T cg17712092 chr4:129076599 LARP1B -0.7 -10.23 -0.48 1.32e-21 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg14705778 chr4:174254825 HMGB2 0.38 6.21 0.32 1.57e-9 Migraine with aura; LIHC trans rs1814175 0.791 rs9787917 chr11:49937281 C/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs2274273 1.000 rs67098772 chr14:55595242 G/A cg01864836 chr14:55583639 NA -0.36 -6.15 -0.32 2.14e-9 Protein biomarker; LIHC cis rs2153535 0.580 rs2184585 chr6:8474168 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs2274273 0.901 rs10140801 chr14:55730404 C/T cg01864836 chr14:55583639 NA -0.4 -7.31 -0.37 1.95e-12 Protein biomarker; LIHC cis rs4268898 0.931 rs2111882 chr2:24434424 A/G cg06627628 chr2:24431161 ITSN2 0.55 7.84 0.39 5.64e-14 Asthma; LIHC cis rs9611565 0.506 rs2024566 chr22:41697338 A/G cg06634786 chr22:41940651 POLR3H -0.53 -6.14 -0.32 2.24e-9 Vitiligo; LIHC cis rs7520050 0.966 rs7539932 chr1:46292354 C/T cg03146154 chr1:46216737 IPP -0.4 -6.54 -0.33 2.27e-10 Red blood cell count;Reticulocyte count; LIHC cis rs6570726 0.791 rs12205752 chr6:145896118 A/G cg05347473 chr6:146136440 FBXO30 0.39 6.14 0.31 2.35e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17854409 1.000 rs6011427 chr20:61496680 C/T cg05147244 chr20:61493195 TCFL5 1.05 9.89 0.47 1.83e-20 Obesity-related traits; LIHC cis rs9549328 0.842 rs6577024 chr13:113634091 G/C cg00071026 chr13:113650936 MCF2L -0.38 -5.93 -0.31 7.3e-9 Systolic blood pressure; LIHC cis rs10089 1.000 rs17764954 chr5:127514436 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.21 0.32 1.55e-9 Ileal carcinoids; LIHC cis rs7903847 0.620 rs9787454 chr10:99155561 A/T cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs4319547 0.695 rs10773152 chr12:122910180 T/C cg23029597 chr12:123009494 RSRC2 -0.53 -7.44 -0.37 8.18e-13 Body mass index; LIHC cis rs1371867 0.846 rs924057 chr8:101266157 A/G cg06002616 chr8:101225028 SPAG1 0.36 6.25 0.32 1.24e-9 Atrioventricular conduction; LIHC cis rs7666738 0.830 rs6811940 chr4:98777898 G/A cg05340658 chr4:99064831 C4orf37 0.64 11.62 0.53 1.6e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.48 0.56 1.05e-29 Prudent dietary pattern; LIHC cis rs4970988 0.501 rs11204713 chr1:150694623 T/A cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Urate levels; LIHC cis rs240764 0.853 rs4461738 chr6:100977940 T/C cg09795085 chr6:101329169 ASCC3 -0.43 -5.78 -0.3 1.65e-8 Neuroticism; LIHC trans rs11098499 0.526 rs10026625 chr4:120280136 T/C cg25214090 chr10:38739885 LOC399744 0.43 6.96 0.35 1.78e-11 Corneal astigmatism; LIHC cis rs9858542 0.953 rs7648841 chr3:49416825 G/A cg03060546 chr3:49711283 APEH -0.46 -6.31 -0.32 8.61e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs11098499 0.738 rs34965784 chr4:120361586 G/C cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs425277 1.000 rs262654 chr1:2089526 G/A cg24578937 chr1:2090814 PRKCZ 0.51 9.2 0.45 3.53e-18 Height; LIHC cis rs13108904 0.901 rs13119532 chr4:1304505 G/C cg00684032 chr4:1343700 KIAA1530 0.53 7.71 0.38 1.35e-13 Obesity-related traits; LIHC cis rs6752107 0.967 rs3792109 chr2:234184417 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.52 7.88 0.39 4.41e-14 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9733 0.744 rs12125650 chr1:150760174 A/G cg18016565 chr1:150552671 MCL1 -0.49 -9.54 -0.46 2.81e-19 Tonsillectomy; LIHC cis rs7897654 0.571 rs7920697 chr10:104633337 T/C cg15744005 chr10:104629667 AS3MT -0.37 -7.54 -0.38 4.23e-13 Schizophrenia; LIHC cis rs763121 0.888 rs2235229 chr22:39124912 A/G cg06544989 chr22:39130855 UNC84B 0.35 5.74 0.3 2.11e-8 Menopause (age at onset); LIHC cis rs8177253 0.965 rs1525889 chr3:133490033 A/C cg12373951 chr3:133503437 NA 0.69 12.43 0.56 1.61e-29 Iron status biomarkers; LIHC cis rs826838 0.967 rs34496261 chr12:39023829 G/A cg13010199 chr12:38710504 ALG10B 0.57 7.03 0.36 1.14e-11 Heart rate; LIHC cis rs116095464 0.558 rs6555058 chr5:226376 C/T cg22857025 chr5:266934 NA 1.44 17.03 0.68 1.51e-47 Breast cancer; LIHC cis rs6088580 0.524 rs1853056 chr20:33262058 C/T cg07148914 chr20:33460835 GGT7 -0.51 -7.21 -0.36 3.56e-12 Glomerular filtration rate (creatinine); LIHC cis rs1728785 1.000 rs1170431 chr16:68605639 T/C cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs6665290 1.000 rs6665290 chr1:227201106 C/T cg10327440 chr1:227177885 CDC42BPA -1.14 -26.8 -0.82 5e-86 Myeloid white cell count; LIHC cis rs12579753 1.000 rs66646148 chr12:82248520 T/G cg07988820 chr12:82153109 PPFIA2 -0.49 -6.02 -0.31 4.51e-9 Resting heart rate; LIHC cis rs937213 0.573 rs3816900 chr15:40302243 C/T cg01081584 chr15:40268610 EIF2AK4 -0.36 -6.05 -0.31 3.75e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs11718455 0.960 rs13081767 chr3:44004468 T/C cg08738300 chr3:44038990 NA 0.52 9.04 0.44 1.19e-17 Coronary artery disease; LIHC trans rs61931739 0.534 rs11052983 chr12:34045787 C/A cg26384229 chr12:38710491 ALG10B 0.47 6.62 0.34 1.36e-10 Morning vs. evening chronotype; LIHC cis rs6952808 0.929 rs2280548 chr7:1976667 G/T cg21782813 chr7:2030301 MAD1L1 0.47 8.1 0.4 9.64e-15 Bipolar disorder and schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21619287 chr16:3767727 TRAP1 -0.5 -6.62 -0.34 1.39e-10 Systolic blood pressure; LIHC cis rs9430161 0.611 rs12081197 chr1:11034239 T/C cg02454025 chr1:11042201 C1orf127 0.96 18.34 0.7 8.49e-53 Ewing sarcoma; LIHC cis rs9527 0.571 rs7904113 chr10:104633114 G/T cg15744005 chr10:104629667 AS3MT -0.42 -9.55 -0.46 2.51e-19 Arsenic metabolism; LIHC cis rs6424115 0.692 rs573361 chr1:24053674 A/T cg15997130 chr1:24165203 NA 0.32 6.55 0.33 2.1e-10 Immature fraction of reticulocytes; LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 9.32e-15 Prudent dietary pattern; LIHC cis rs4555082 0.874 rs11625098 chr14:105756891 A/G cg13114125 chr14:105738426 BRF1 -0.79 -9.98 -0.47 9.32e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs7216064 0.906 rs78452260 chr17:65848522 G/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.59e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2239815 0.515 rs9625595 chr22:29238913 C/T cg15103426 chr22:29168792 CCDC117 0.43 5.81 0.3 1.45e-8 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC cis rs4820294 1.000 rs62236665 chr22:38059847 C/A cg00292662 chr22:38071168 LGALS1 0.63 10.04 0.48 6.04e-21 Fat distribution (HIV); LIHC cis rs10792665 0.541 rs1318423 chr11:82615502 T/C cg24227371 chr11:82718527 RAB30 -0.28 -6.54 -0.33 2.25e-10 Obesity-related traits; LIHC cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg11890956 chr21:40555474 PSMG1 -0.46 -7.43 -0.37 9.04e-13 Cognitive function; LIHC cis rs921968 0.643 rs589967 chr2:219445165 T/C cg02985541 chr2:219472218 PLCD4 0.44 8.5 0.42 5.86e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.38 0.52 1.13e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg00656387 chr3:40428638 ENTPD3 0.48 7.84 0.39 5.68e-14 Renal cell carcinoma; LIHC cis rs4718428 0.705 rs10267335 chr7:66403220 G/T cg18252515 chr7:66147081 NA -0.7 -9.6 -0.46 1.78e-19 Corneal structure; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg26338869 chr17:61819248 STRADA 0.5 6.5 0.33 2.87e-10 Height; LIHC cis rs637571 0.544 rs55704213 chr11:65730002 C/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.82 0.43 5.99e-17 Eosinophil percentage of white cells; LIHC trans rs1005277 0.579 rs1621040 chr10:38497232 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.55 0.33 2.07e-10 Extrinsic epigenetic age acceleration; LIHC cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2625529 0.641 rs2035379 chr15:72293202 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.81 -0.3 1.47e-8 Red blood cell count; LIHC cis rs9583531 0.550 rs7985098 chr13:111386416 G/A cg24331049 chr13:111365604 ING1 0.64 10.73 0.5 2.47e-23 Coronary artery disease; LIHC cis rs8072100 1.000 rs4375701 chr17:45712218 C/T cg08085267 chr17:45401833 C17orf57 -0.56 -8.33 -0.41 2e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs61677309 1.000 rs55789743 chr11:118171949 C/A cg06090739 chr11:118230722 UBE4A 0.34 6.32 0.32 8.33e-10 Lung cancer in ever smokers; LIHC cis rs2153535 0.580 rs1889715 chr6:8443475 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.5 0.42 5.96e-16 Motion sickness; LIHC cis rs2243480 0.901 rs3813708 chr7:65305632 C/A cg18252515 chr7:66147081 NA -1.3 -16.6 -0.67 8.39e-46 Diabetic kidney disease; LIHC cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.42 0.53 8.07e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17327406 chr4:6303265 WFS1 -0.41 -6.19 -0.32 1.76e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7523273 0.565 rs2796234 chr1:207900695 T/A cg22525895 chr1:207977042 MIR29B2 -0.54 -8.24 -0.41 3.61e-15 Schizophrenia; LIHC cis rs2455799 0.573 rs2470520 chr3:15762920 C/T cg12698662 chr3:15914712 MIR563 -0.39 -7.27 -0.37 2.46e-12 Mean platelet volume; LIHC cis rs2952156 0.883 rs12150603 chr17:37834715 G/A cg00129232 chr17:37814104 STARD3 -0.55 -10.66 -0.5 4.14e-23 Asthma; LIHC cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.18 12.59 0.56 4e-30 Platelet count; LIHC cis rs10056811 0.538 rs56174528 chr5:74400516 G/C cg00601450 chr5:74908170 NA 0.55 6.38 0.33 5.82e-10 Coronary artery disease; LIHC cis rs7917772 0.582 rs10883744 chr10:104347247 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6547741 1.000 rs1972669 chr2:27767107 T/G cg27432699 chr2:27873401 GPN1 0.72 11.54 0.53 3.16e-26 Oral cavity cancer; LIHC cis rs7100689 0.646 rs1934694 chr10:82125325 G/A cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.43 7.12 0.36 6.4e-12 Height; LIHC cis rs34172651 0.917 rs200533 chr16:24754771 C/T cg00339695 chr16:24857497 SLC5A11 -0.32 -5.77 -0.3 1.75e-8 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.921 rs2143695 chr22:41728620 A/G cg03806693 chr22:41940476 POLR3H -0.47 -6.16 -0.32 2e-9 Vitiligo; LIHC cis rs8072100 0.837 rs62074055 chr17:45771933 G/C cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.37 -6.05 -0.31 3.86e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs116095464 0.558 rs9312977 chr5:221916 G/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs11673344 0.704 rs1644711 chr19:37417322 C/G cg27390819 chr19:37464633 NA -0.48 -5.82 -0.3 1.35e-8 Obesity-related traits; LIHC cis rs9921222 1.000 rs10794639 chr16:377367 A/G cg00101154 chr16:420108 MRPL28 -0.48 -6.8 -0.34 4.79e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs6449957 0.639 rs831227 chr5:67517646 A/C cg23036683 chr5:67512108 NA 0.51 7.62 0.38 2.5e-13 Cleft lip with or without cleft palate; LIHC cis rs10751667 0.961 rs6421967 chr11:983966 T/C cg06064525 chr11:970664 AP2A2 -0.49 -12.04 -0.55 4.54e-28 Alzheimer's disease (late onset); LIHC cis rs1144333 1.000 rs1144333 chr1:76275100 A/G cg03433033 chr1:76189801 ACADM -0.56 -8.58 -0.42 3.33e-16 Attention function in attention deficit hyperactive disorder; LIHC trans rs1814175 0.509 rs60698301 chr11:49877672 G/A cg15704280 chr7:45808275 SEPT13 -0.95 -19.73 -0.73 2.22e-58 Height; LIHC cis rs2304069 0.913 rs3812009 chr5:149380159 G/C cg12661370 chr5:149340060 SLC26A2 0.54 6.5 0.33 2.9e-10 HIV-1 control; LIHC cis rs4820539 1.000 rs4822360 chr22:23482460 A/G cg21100191 chr22:23484243 RTDR1 0.86 15.61 0.64 7.81e-42 Bone mineral density; LIHC cis rs801193 0.591 rs9986881 chr7:66173040 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.42 9.23 0.45 2.86e-18 Aortic root size; LIHC cis rs911119 0.913 rs6048929 chr20:23588855 T/C cg16589663 chr20:23618590 CST3 0.71 7.5 0.38 5.61e-13 Chronic kidney disease; LIHC cis rs11718455 0.960 rs1852036 chr3:44003862 C/T cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg18305652 chr10:134549665 INPP5A 0.55 8.98 0.44 1.9e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9473924 0.505 rs7753025 chr6:50858352 A/C cg14470998 chr6:50812995 TFAP2B 0.94 10.91 0.51 5.57e-24 Body mass index; LIHC cis rs7829975 0.667 rs1877119 chr8:8707197 C/G cg06636001 chr8:8085503 FLJ10661 0.42 7.26 0.37 2.66e-12 Mood instability; LIHC cis rs3008870 0.920 rs12132532 chr1:67457015 G/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC trans rs9951602 0.512 rs12454617 chr18:76656007 C/T cg02800362 chr5:177631904 HNRNPAB 0.65 10.31 0.49 6.92e-22 Obesity-related traits; LIHC cis rs3110496 1.000 rs3110496 chr17:27917771 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.51 6.96 0.35 1.8e-11 Height; LIHC cis rs9549328 0.800 rs9549620 chr13:113633421 T/A cg18289306 chr13:113640169 MCF2L 0.42 6.65 0.34 1.13e-10 Systolic blood pressure; LIHC cis rs9513627 0.512 rs9517759 chr13:100180108 T/G cg25919922 chr13:100150906 NA 1.03 17.37 0.68 7.07e-49 Obesity-related traits; LIHC cis rs2075165 0.901 rs1804999 chr1:156219450 A/G cg07234388 chr1:156261841 TMEM79 0.51 8.77 0.43 8.74e-17 Tonsillectomy; LIHC cis rs67478160 0.654 rs1997913 chr14:104213960 C/T cg08213375 chr14:104286397 PPP1R13B 0.66 13.02 0.58 9.38e-32 Schizophrenia; LIHC cis rs7586673 0.866 rs747003 chr2:161916409 C/T cg16506815 chr2:162101123 NA -0.46 -7.49 -0.38 5.74e-13 Intelligence (multi-trait analysis); LIHC cis rs963731 0.579 rs2168042 chr2:39273536 C/T cg04010122 chr2:39346883 SOS1 -0.7 -6.48 -0.33 3.22e-10 Corticobasal degeneration; LIHC cis rs17685 0.796 rs3757594 chr7:75678644 G/A cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.21 0.32 1.51e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg12310025 chr6:25882481 NA -0.53 -6.52 -0.33 2.59e-10 Intelligence (multi-trait analysis); LIHC cis rs600806 0.778 rs10776698 chr1:110013630 C/T cg16275483 chr1:110013120 SYPL2 -0.49 -6.22 -0.32 1.45e-9 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.791 rs10985004 chr9:123484937 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.81 13.37 0.59 4.48e-33 Hip circumference adjusted for BMI; LIHC cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg19626725 chr5:178986131 RUFY1 0.38 5.9 0.3 8.74e-9 Lung cancer; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg07332563 chr6:291687 DUSP22 -0.53 -7.64 -0.38 2.22e-13 Menopause (age at onset); LIHC cis rs6912958 0.559 rs242287 chr6:88071825 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.53 9.23 0.45 2.91e-18 Monocyte percentage of white cells; LIHC cis rs8141529 0.748 rs5752826 chr22:29269808 A/G cg15103426 chr22:29168792 CCDC117 0.57 9.26 0.45 2.37e-18 Lymphocyte counts; LIHC cis rs17685 0.712 rs56965035 chr7:75795670 G/A cg16684958 chr7:75615977 POR 0.52 8.59 0.42 3.22e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7408868 0.908 rs10416865 chr19:15277601 T/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.79 -0.3 1.61e-8 Pulse pressure; LIHC cis rs7777484 0.534 rs2533890 chr7:2828743 C/T cg18446336 chr7:2847575 GNA12 -0.33 -6.52 -0.33 2.52e-10 Height; LIHC cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg09904177 chr6:26538194 HMGN4 0.57 11.21 0.52 4.9e-25 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.614 rs34843288 chr17:57103140 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.12 0.58 4.05e-32 Cognitive test performance; LIHC cis rs12478296 1.000 rs7420157 chr2:243005204 G/A cg06360820 chr2:242988706 NA -0.82 -12.26 -0.55 6.88e-29 Obesity-related traits; LIHC cis rs9768139 0.658 rs28425474 chr7:158116360 C/T cg06219351 chr7:158114137 PTPRN2 -0.21 -5.86 -0.3 1.09e-8 Calcium levels; LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg04234412 chr22:24373322 LOC391322 -0.51 -7.44 -0.37 8.47e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs16958440 1.000 rs16958432 chr18:44631773 G/A cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.61e-11 Sitting height ratio; LIHC cis rs9486719 0.843 rs2499793 chr6:96846402 A/C cg06623918 chr6:96969491 KIAA0776 0.69 6.69 0.34 8.95e-11 Migraine;Coronary artery disease; LIHC cis rs12500138 0.572 rs56681900 chr4:166180240 A/G cg25064052 chr4:166216151 KLHL2 -0.65 -6.01 -0.31 4.63e-9 Cognitive function; LIHC cis rs7666738 0.515 rs13131874 chr4:98779183 A/G cg05340658 chr4:99064831 C4orf37 0.49 6.36 0.33 6.5e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs4332037 0.901 rs7791899 chr7:1935988 T/C cg11693508 chr17:37793320 STARD3 0.73 7.53 0.38 4.48e-13 Bipolar disorder; LIHC trans rs9329221 0.905 rs4433149 chr8:10249268 A/T cg06636001 chr8:8085503 FLJ10661 -0.5 -6.91 -0.35 2.37e-11 Neuroticism; LIHC cis rs7129220 0.512 rs11042666 chr11:10227393 A/T cg01453529 chr11:10209919 SBF2 -0.41 -7.64 -0.38 2.2e-13 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs8062405 0.964 rs11864107 chr16:28885931 T/C cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16715692 chr19:1104863 GPX4 -0.39 -6.12 -0.31 2.54e-9 Pancreatic cancer; LIHC cis rs3008870 1.000 rs35365746 chr1:67438900 G/A cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs9300255 0.602 rs1727294 chr12:123616514 A/G cg00376283 chr12:123451042 ABCB9 0.6 8.06 0.4 1.28e-14 Neutrophil percentage of white cells; LIHC cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.56 -9.33 -0.45 1.32e-18 Prudent dietary pattern; LIHC cis rs68170813 0.599 rs12532849 chr7:106959226 A/C cg02696742 chr7:106810147 HBP1 -0.51 -5.91 -0.3 8.15e-9 Coronary artery disease; LIHC cis rs11690935 0.921 rs7594711 chr2:172895637 T/G cg13550731 chr2:172543902 DYNC1I2 -0.91 -15.92 -0.65 4.35e-43 Schizophrenia; LIHC cis rs6450176 1.000 rs6450175 chr5:53297824 C/T ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs75908454 1.000 rs75999861 chr6:169827317 T/C cg19338460 chr6:170058176 WDR27 -0.87 -7.81 -0.39 7.2e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs17401966 0.800 rs12122029 chr1:10339822 G/A cg15208524 chr1:10270712 KIF1B 0.38 5.85 0.3 1.18e-8 Hepatocellular carcinoma; LIHC cis rs1144333 1.000 rs1586936 chr1:76366877 T/C cg10523679 chr1:76189770 ACADM 0.46 6.55 0.33 2.13e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs9296092 0.521 rs56332659 chr6:33537887 T/C cg13560919 chr6:33536144 NA -0.41 -6.84 -0.35 3.6e-11 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs10771431 0.597 rs10771412 chr12:9354353 A/C cg08997352 chr12:9597637 DDX12 -0.49 -7.61 -0.38 2.62e-13 Breast size; LIHC cis rs3753275 0.690 rs6697997 chr1:8609111 A/G cg20416874 chr1:8611966 RERE -0.5 -6.48 -0.33 3.18e-10 Educational attainment; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01091156 chr16:87991122 BANP 0.42 6.39 0.33 5.38e-10 Longevity; LIHC cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg05025164 chr4:1340916 KIAA1530 -0.75 -12.39 -0.56 2.2e-29 Longevity; LIHC cis rs858239 0.570 rs10271613 chr7:23162586 G/A cg23682824 chr7:23144976 KLHL7 0.44 6.56 0.33 1.97e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2274273 0.870 rs1109170 chr14:55785788 A/C cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.37e-9 Protein biomarker; LIHC cis rs17376456 0.809 rs13177800 chr5:93307350 T/C cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs2997447 0.655 rs11247852 chr1:26383125 C/G cg19633962 chr1:26362018 EXTL1 0.65 7.76 0.39 9.58e-14 QRS complex (12-leadsum); LIHC cis rs2668423 0.502 rs7254913 chr19:1388320 A/G cg02639931 chr19:1387894 NDUFS7 0.84 16.2 0.66 3.25e-44 Nonalcoholic fatty liver disease; LIHC cis rs6667605 0.527 rs6673993 chr1:2552071 T/C cg18854424 chr1:2615690 NA 0.34 7.54 0.38 4.23e-13 Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs920590 0.796 rs11778257 chr8:19634598 A/T cg03894339 chr8:19674705 INTS10 0.41 5.83 0.3 1.26e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs9837602 0.529 rs793458 chr3:99520169 C/T cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.83 -0.3 1.26e-8 Breast cancer; LIHC cis rs7828089 0.934 rs12544427 chr8:22263115 C/T cg12081754 chr8:22256438 SLC39A14 -0.51 -7.95 -0.39 2.73e-14 Verbal declarative memory; LIHC cis rs7208859 0.673 rs11080138 chr17:29224542 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.56e-13 Prudent dietary pattern; LIHC cis rs1059312 0.669 rs11059917 chr12:129287925 T/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.65 -11.98 -0.54 7.16e-28 Systemic lupus erythematosus; LIHC cis rs758324 0.947 rs6861174 chr5:131156129 A/G cg06307176 chr5:131281290 NA 0.4 5.73 0.3 2.18e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs9611565 0.512 rs5758464 chr22:42171300 A/G cg03806693 chr22:41940476 POLR3H 0.86 8.17 0.4 6.14e-15 Vitiligo; LIHC cis rs7572733 0.534 rs1607374 chr2:198800440 A/G cg00792783 chr2:198669748 PLCL1 0.46 6.58 0.34 1.75e-10 Dermatomyositis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18281101 chr1:157015843 ARHGEF11 0.45 6.31 0.32 8.44e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.51 -7.35 -0.37 1.52e-12 Lymphocyte counts; LIHC cis rs7264396 0.635 rs6058382 chr20:34553948 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg11645453 chr3:52864694 ITIH4 0.22 5.95 0.31 6.75e-9 Bipolar disorder; LIHC cis rs2404602 0.622 rs9635380 chr15:77103479 A/G cg23625390 chr15:77176239 SCAPER -0.5 -7.91 -0.39 3.65e-14 Blood metabolite levels; LIHC cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg13257436 chr8:145726034 PPP1R16A 0.36 6.38 0.33 5.62e-10 Age at first birth; LIHC cis rs559928 0.606 rs76653616 chr11:63936139 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.36 0.37 1.35e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs6951245 0.810 rs117800627 chr7:1081075 G/C cg21664854 chr7:1097933 C7orf50;GPR146 0.72 5.83 0.3 1.28e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2070433 1.000 rs2070433 chr21:47961386 G/A cg12379764 chr21:47803548 PCNT 0.64 9.18 0.44 4.33e-18 Lymphocyte counts; LIHC cis rs34779708 0.931 rs2384289 chr10:35343525 G/A cg03585969 chr10:35415529 CREM 0.8 11.9 0.54 1.48e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11229555 0.957 rs10896796 chr11:58394256 A/G cg15696309 chr11:58395628 NA -0.73 -8.92 -0.43 2.81e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1008375 1.000 rs7673500 chr4:17621383 C/T cg02297831 chr4:17616191 MED28 0.49 7.58 0.38 3.19e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4268898 0.662 rs2303296 chr2:24432839 A/G cg06627628 chr2:24431161 ITSN2 -0.73 -9.61 -0.46 1.67e-19 Asthma; LIHC cis rs4820539 1.000 rs2267003 chr22:23457098 A/G cg14186256 chr22:23484241 RTDR1 0.92 18.75 0.71 1.84e-54 Bone mineral density; LIHC cis rs4319547 0.956 rs10847179 chr12:123040985 T/C cg23029597 chr12:123009494 RSRC2 -0.52 -7.42 -0.37 9.14e-13 Body mass index; LIHC cis rs4803468 1.000 rs3810174 chr19:41904165 C/T cg14132834 chr19:41945861 ATP5SL -0.44 -6.61 -0.34 1.48e-10 Height; LIHC cis rs2580764 0.565 rs6545466 chr2:55228392 C/T cg09592903 chr2:55203963 RTN4 -0.72 -13.47 -0.59 1.86e-33 Mean platelet volume; LIHC cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg00484396 chr16:3507460 NAT15 0.42 7.21 0.36 3.53e-12 Tuberculosis; LIHC cis rs7772486 0.790 rs9497435 chr6:146265340 C/A cg05347473 chr6:146136440 FBXO30 -0.35 -5.73 -0.3 2.2e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 0.967 rs339101 chr3:161064193 A/T cg04691961 chr3:161091175 C3orf57 -0.41 -6.43 -0.33 4.24e-10 Morning vs. evening chronotype; LIHC cis rs9393692 0.905 rs9379843 chr6:26289435 A/G cg05868516 chr6:26286170 HIST1H4H 0.39 5.93 0.31 7.46e-9 Educational attainment; LIHC cis rs2289583 0.642 rs7162941 chr15:75385622 C/T cg15902774 chr15:75289873 SCAMP5 0.33 5.95 0.31 6.73e-9 Systemic lupus erythematosus; LIHC cis rs13118159 0.934 rs4974608 chr4:1356780 C/T cg13395646 chr4:1353034 KIAA1530 -0.66 -9.0 -0.44 1.57e-17 Longevity; LIHC trans rs35110281 0.607 rs4819212 chr21:44977455 G/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.5 6.85 0.35 3.36e-11 Mean corpuscular volume; LIHC cis rs72843506 0.656 rs111249650 chr17:19911830 A/T cg12065943 chr17:19881925 AKAP10 -0.41 -7.0 -0.35 1.35e-11 Schizophrenia; LIHC cis rs6088580 0.602 rs6058064 chr20:33086622 A/G cg08999081 chr20:33150536 PIGU 0.68 13.52 0.59 1.12e-33 Glomerular filtration rate (creatinine); LIHC cis rs2599510 1.000 rs2599510 chr2:32826002 A/G cg02381751 chr2:32503542 YIPF4 0.52 6.98 0.35 1.5e-11 Interleukin-18 levels; LIHC cis rs4862750 0.914 rs1991255 chr4:187875340 G/A cg03452623 chr4:187889614 NA -0.31 -7.92 -0.39 3.44e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs40363 0.645 rs250629 chr16:3525431 C/A cg21433313 chr16:3507492 NAT15 0.47 7.81 0.39 7.03e-14 Tuberculosis; LIHC cis rs3796352 1.000 rs71617204 chr3:53042951 G/A cg07884673 chr3:53033167 SFMBT1 0.92 6.74 0.34 6.85e-11 Immune reponse to smallpox (secreted IL-2); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg26788993 chr3:159706828 IL12A -0.41 -6.14 -0.32 2.33e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2278034 0.578 rs881753 chr3:195606770 C/T cg01181863 chr3:195395398 SDHAP2 0.48 6.74 0.34 6.84e-11 Bronchopulmonary dysplasia; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg09033563 chr22:24373618 LOC391322 -0.47 -6.5 -0.33 2.88e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6598955 0.724 rs6656716 chr1:26563105 G/A cg00852783 chr1:26633632 UBXN11 0.49 8.17 0.4 5.9e-15 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25338623 chr11:67250427 AIP 0.45 6.06 0.31 3.5e-9 Pancreatic cancer; LIHC cis rs12477438 0.501 rs12992218 chr2:99753834 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.82 0.65 1.12e-42 Chronic sinus infection; LIHC cis rs7937682 0.855 rs490897 chr11:111487914 A/G cg09085632 chr11:111637200 PPP2R1B -0.89 -10.57 -0.5 8.53e-23 Primary sclerosing cholangitis; LIHC cis rs6545883 0.929 rs12612982 chr2:61747355 G/A cg14146966 chr2:61757674 XPO1 0.48 8.47 0.42 7.3e-16 Tuberculosis; LIHC cis rs12478296 1.000 rs73007140 chr2:243010756 T/C cg06360820 chr2:242988706 NA -0.81 -12.2 -0.55 1.11e-28 Obesity-related traits; LIHC cis rs11718455 1.000 rs17076273 chr3:44020113 A/G cg08738300 chr3:44038990 NA 0.52 8.91 0.43 3.02e-17 Coronary artery disease; LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg03721293 chr16:90014378 DEF8 0.43 7.01 0.35 1.25e-11 Skin colour saturation; LIHC cis rs4423214 0.592 rs10898234 chr11:71236684 A/G cg05163923 chr11:71159392 DHCR7 -0.59 -7.26 -0.37 2.69e-12 Vitamin D levels; LIHC cis rs10206020 0.921 rs2280127 chr2:1546531 C/T cg01028140 chr2:1542097 TPO -0.45 -7.23 -0.36 3.09e-12 IgG glycosylation; LIHC trans rs10213084 1.000 rs28755940 chr4:147480048 A/C cg18061433 chr10:21435895 C10orf113;NEBL 0.52 6.23 0.32 1.37e-9 Heart rate; LIHC cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.06e-10 Alzheimer's disease; LIHC cis rs6570726 0.577 rs406868 chr6:145809983 C/T cg23711669 chr6:146136114 FBXO30 0.63 9.79 0.47 4.19e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs1215050 0.740 rs1214997 chr4:99041533 A/T cg05340658 chr4:99064831 C4orf37 0.41 6.25 0.32 1.21e-9 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs61931739 0.500 rs11053218 chr12:34474792 A/C cg26384229 chr12:38710491 ALG10B -0.75 -8.67 -0.42 1.79e-16 Morning vs. evening chronotype; LIHC cis rs2741335 0.876 rs2741338 chr8:27335734 C/T cg07150473 chr8:27338183 CHRNA2 0.46 6.42 0.33 4.42e-10 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC cis rs11030122 0.673 rs10767767 chr11:4003678 C/T cg18678763 chr11:4115507 RRM1 -0.56 -8.26 -0.41 3.21e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs7772486 0.748 rs2748484 chr6:146333653 C/T cg23711669 chr6:146136114 FBXO30 0.6 10.56 0.5 9.19e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs9296092 0.538 rs7761268 chr6:33519300 C/T cg13560919 chr6:33536144 NA -0.38 -6.44 -0.33 4.1e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs60871478 1.000 rs4721124 chr7:823761 T/C cg05535760 chr7:792225 HEATR2 0.78 11.05 0.51 1.81e-24 Cerebrospinal P-tau181p levels; LIHC cis rs1799949 0.965 rs8070179 chr17:41202688 G/A cg23758822 chr17:41437982 NA 0.95 17.52 0.69 1.67e-49 Menopause (age at onset); LIHC cis rs12497850 0.931 rs4974079 chr3:48906469 T/G cg07636037 chr3:49044803 WDR6 0.93 16.74 0.67 2.27e-46 Parkinson's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01479911 chr17:7145805 GABARAP -0.56 -6.4 -0.33 5.04e-10 Systolic blood pressure; LIHC cis rs9929218 0.953 rs3118235 chr16:68732977 A/G cg01231543 chr16:68741748 NA -0.38 -5.8 -0.3 1.55e-8 Colorectal cancer; LIHC cis rs11031096 0.563 rs12281849 chr11:4224832 C/T cg18678763 chr11:4115507 RRM1 -0.43 -6.45 -0.33 3.91e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6586163 0.527 rs12775501 chr10:90750909 C/T cg03111039 chr10:90751583 FAS;ACTA2 0.79 12.72 0.57 1.33e-30 Chronic lymphocytic leukemia; LIHC cis rs2842992 0.709 rs1853257 chr6:160212710 C/G cg16489826 chr6:160211363 TCP1;MRPL18 0.53 9.25 0.45 2.58e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg04267008 chr7:1944627 MAD1L1 -0.59 -9.23 -0.45 2.97e-18 Bipolar disorder and schizophrenia; LIHC cis rs9346649 0.630 rs6913441 chr6:168491271 C/T cg02770688 chr6:168491649 NA 0.31 5.89 0.3 9.39e-9 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; LIHC cis rs9733 0.650 rs3738485 chr1:150552392 C/G cg18016565 chr1:150552671 MCL1 -0.54 -11.08 -0.51 1.43e-24 Tonsillectomy; LIHC cis rs600806 0.850 rs10858095 chr1:109962642 G/C cg16275483 chr1:110013120 SYPL2 -0.48 -5.96 -0.31 6.44e-9 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.898 rs72786298 chr2:24083011 C/T cg08917208 chr2:24149416 ATAD2B 0.99 8.7 0.43 1.39e-16 Lymphocyte counts; LIHC cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg11644478 chr21:40555479 PSMG1 0.81 10.44 0.49 2.52e-22 Cognitive function; LIHC cis rs9457247 0.602 rs2157388 chr6:167481912 G/A cg07741184 chr6:167504864 NA 0.34 7.59 0.38 3.13e-13 Crohn's disease; LIHC trans rs1814175 0.669 rs12364577 chr11:49707361 A/C cg15704280 chr7:45808275 SEPT13 -0.68 -11.78 -0.54 3.92e-27 Height; LIHC cis rs1144333 1.000 rs17097863 chr1:76468787 T/G cg22875332 chr1:76189707 ACADM 0.39 6.1 0.31 2.9e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs11031096 0.711 rs12270809 chr11:4206537 G/A cg18678763 chr11:4115507 RRM1 -0.39 -5.82 -0.3 1.36e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1538970 0.924 rs1007858 chr1:45912005 C/T cg24296786 chr1:45957014 TESK2 -0.51 -7.3 -0.37 1.97e-12 Platelet count; LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs6467136 0.540 rs56216302 chr7:127180679 G/A cg25922125 chr7:127225783 GCC1 -0.45 -5.84 -0.3 1.25e-8 Type 2 diabetes; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19498110 chr22:17590091 IL17RA -0.44 -7.42 -0.37 9.38e-13 Calcium levels; LIHC cis rs8192917 1.000 rs2273844 chr14:25103414 G/A cg03875678 chr14:25103546 GZMB 0.4 7.08 0.36 8.45e-12 Vitiligo; LIHC cis rs1046896 0.594 rs4075209 chr17:80800027 G/T cg02711726 chr17:80685570 FN3KRP -0.44 -8.16 -0.4 6.3e-15 Glycated hemoglobin levels; LIHC cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg18252515 chr7:66147081 NA -1.27 -16.34 -0.66 9.2e-45 Diabetic kidney disease; LIHC cis rs1023500 0.505 rs134899 chr22:42683030 T/G cg00645731 chr22:42541494 CYP2D7P1 0.38 6.51 0.33 2.74e-10 Schizophrenia; LIHC cis rs4319547 0.656 rs2173582 chr12:122824694 A/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.19 -0.36 4.17e-12 Body mass index; LIHC cis rs10193935 1.000 rs10195776 chr2:42425098 G/A cg27598129 chr2:42591480 NA -0.73 -11.26 -0.52 3.12e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs9814567 1.000 rs13059720 chr3:134242021 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2642442 0.962 rs2807834 chr1:220970593 A/C cg04704887 chr1:220970030 MOSC1 -0.45 -6.1 -0.31 2.84e-9 Cholesterol, total;LDL cholesterol; LIHC cis rs1552244 0.882 rs68080705 chr3:10025743 C/T cg13047869 chr3:10149882 C3orf24 0.43 5.91 0.3 8.11e-9 Alzheimer's disease; LIHC cis rs7617773 0.780 rs77044321 chr3:48349314 C/T cg11946769 chr3:48343235 NME6 0.91 11.33 0.52 1.81e-25 Coronary artery disease; LIHC cis rs12478296 0.591 rs12468297 chr2:242996474 A/G cg18898632 chr2:242989856 NA -0.38 -5.73 -0.3 2.25e-8 Obesity-related traits; LIHC trans rs2270221 0.767 rs12701153 chr7:31906164 G/T cg06873401 chr5:77792105 LHFPL2 0.49 6.05 0.31 3.72e-9 Endometriosis; LIHC cis rs7659604 0.728 rs3924987 chr4:122689784 G/T cg19748678 chr4:122722346 EXOSC9 0.64 10.69 0.5 3.21e-23 Type 2 diabetes; LIHC cis rs4888262 0.526 rs4404098 chr16:74570050 G/A cg01733217 chr16:74700730 RFWD3 0.79 15.27 0.64 1.7e-40 Testicular germ cell tumor; LIHC cis rs7474896 0.537 rs2749589 chr10:38266870 C/T cg25427524 chr10:38739819 LOC399744 0.46 6.15 0.32 2.17e-9 Obesity (extreme); LIHC trans rs11088226 0.581 rs2833862 chr21:33884390 A/G cg09050820 chr6:167586206 TCP10L2 0.47 7.26 0.37 2.6e-12 Gastritis; LIHC trans rs2243480 0.803 rs36127118 chr7:65565505 A/G cg10756647 chr7:56101905 PSPH 1.06 13.29 0.58 8.51e-33 Diabetic kidney disease; LIHC cis rs7659604 0.702 rs6826506 chr4:122710865 T/G cg19748678 chr4:122722346 EXOSC9 0.67 10.91 0.51 5.54e-24 Type 2 diabetes; LIHC cis rs4423214 0.592 rs7130829 chr11:71237702 A/T cg05163923 chr11:71159392 DHCR7 -0.59 -7.23 -0.36 3.18e-12 Vitamin D levels; LIHC trans rs3942852 0.774 rs924715 chr11:48181060 G/A cg03929089 chr4:120376271 NA -0.55 -7.58 -0.38 3.26e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs12926788 0.546 rs200537 chr16:24747787 G/C cg04756594 chr16:24857601 SLC5A11 -0.58 -8.73 -0.43 1.18e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10256972 0.640 rs10271082 chr7:1081562 G/C cg04025307 chr7:1156635 C7orf50 0.4 6.32 0.32 8.31e-10 Longevity;Endometriosis; LIHC cis rs10949834 0.618 rs810551 chr7:73492093 C/G cg07137043 chr7:73588983 EIF4H -0.51 -6.04 -0.31 3.99e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs9596863 1.000 rs1458268 chr13:54405594 C/T ch.13.53330881F chr13:54432880 NA -0.43 -6.06 -0.31 3.61e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg03806693 chr22:41940476 POLR3H 1.03 12.62 0.56 3.16e-30 Vitiligo; LIHC cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 6.03 0.31 4.31e-9 Schizophrenia; LIHC cis rs2834188 0.669 rs1467845 chr21:34666376 A/G cg14352951 chr21:34696688 IFNAR1 0.42 6.02 0.31 4.62e-9 Narcolepsy; LIHC cis rs17376456 0.825 rs34592268 chr5:93232751 G/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg05564831 chr3:52568323 NT5DC2 0.36 5.93 0.31 7.29e-9 Electroencephalogram traits; LIHC cis rs7659604 0.539 rs11731917 chr4:122783233 G/A cg20573242 chr4:122745356 CCNA2 0.53 7.75 0.39 1.07e-13 Type 2 diabetes; LIHC cis rs4319547 0.626 rs10744210 chr12:122931793 A/G cg05707623 chr12:122985044 ZCCHC8 -0.58 -7.57 -0.38 3.53e-13 Body mass index; LIHC cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg20295408 chr7:1910781 MAD1L1 -0.5 -7.18 -0.36 4.44e-12 Bipolar disorder and schizophrenia; LIHC cis rs17125944 0.615 rs7146179 chr14:53298853 A/G cg00686598 chr14:53173677 PSMC6 -0.88 -10.38 -0.49 4.11e-22 Alzheimer's disease (late onset); LIHC cis rs10744422 1.000 rs921808 chr12:123323135 A/G cg18912006 chr12:123335444 HIP1R 0.58 7.11 0.36 6.8e-12 Schizophrenia; LIHC cis rs1577917 0.771 rs4145082 chr6:86352016 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -12.5 -0.56 8.42e-30 Response to antipsychotic treatment; LIHC cis rs12477438 0.520 rs6542863 chr2:99725138 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.68 0.78 3.75e-70 Chronic sinus infection; LIHC cis rs11098499 0.954 rs6820115 chr4:120398182 T/C cg09307838 chr4:120376055 NA 0.67 10.75 0.5 2.04e-23 Corneal astigmatism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23797839 chr10:60094994 UBE2D1 0.5 6.96 0.35 1.76e-11 Lung function (FEV1/FVC); LIHC cis rs763121 0.853 rs2284073 chr22:39105948 T/C cg06022373 chr22:39101656 GTPBP1 0.73 14.34 0.61 7.33e-37 Menopause (age at onset); LIHC cis rs116095464 0.614 rs78905930 chr5:246560 G/A cg22857025 chr5:266934 NA -1.48 -17.71 -0.69 2.89e-50 Breast cancer; LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg00656387 chr3:40428638 ENTPD3 0.5 8.29 0.41 2.68e-15 Renal cell carcinoma; LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg18279126 chr7:2041391 MAD1L1 0.38 6.39 0.33 5.37e-10 Bipolar disorder and schizophrenia; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg20604317 chr20:4129314 SMOX 0.44 6.56 0.33 2.05e-10 Migraine with aura; LIHC cis rs1008375 0.835 rs9760627 chr4:17651508 C/T cg15017067 chr4:17643749 FAM184B 0.33 5.78 0.3 1.68e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12478296 0.786 rs13409307 chr2:242995499 G/C cg18898632 chr2:242989856 NA -0.51 -7.27 -0.37 2.48e-12 Obesity-related traits; LIHC trans rs11039798 0.688 rs12277029 chr11:48852833 G/T cg15704280 chr7:45808275 SEPT13 0.63 6.57 0.33 1.86e-10 Axial length; LIHC trans rs8073060 0.859 rs17550268 chr17:33874678 T/C cg19694781 chr19:47549865 TMEM160 0.83 8.48 0.42 6.99e-16 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg00166722 chr3:10149974 C3orf24 0.47 5.86 0.3 1.12e-8 Alzheimer's disease; LIHC trans rs1728785 1.000 rs7202306 chr16:68587684 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.36 0.33 6.63e-10 Ulcerative colitis; LIHC cis rs17376456 0.757 rs6859757 chr5:93206042 C/T cg25358565 chr5:93447407 FAM172A 1.08 9.74 0.47 5.89e-20 Diabetic retinopathy; LIHC cis rs11148252 0.967 rs11620062 chr13:52994026 T/G cg00495681 chr13:53174319 NA 0.42 7.02 0.36 1.18e-11 Lewy body disease; LIHC cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs909341 0.909 rs2236510 chr20:62368804 C/T cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.74e-11 Atopic dermatitis; LIHC cis rs1395 0.744 rs62130709 chr2:27505782 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -5.94 -0.31 7.05e-9 Blood metabolite levels; LIHC cis rs10911232 0.507 rs10797833 chr1:183044067 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 4.01e-23 Hypertriglyceridemia; LIHC cis rs7615952 0.641 rs6805074 chr3:125772274 T/A cg05084668 chr3:125655381 ALG1L -0.41 -6.38 -0.33 5.63e-10 Blood pressure (smoking interaction); LIHC cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg10802521 chr3:52805072 NEK4 -0.39 -6.24 -0.32 1.31e-9 Bipolar disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24113505 chr7:92861286 CCDC132 0.44 6.45 0.33 3.93e-10 Cognitive function; LIHC cis rs3784262 1.000 rs10851630 chr15:58242148 C/T cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.18 -0.32 1.85e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs4700695 0.925 rs796728 chr5:65382500 C/T cg21114390 chr5:65439923 SFRS12 -0.46 -6.11 -0.31 2.76e-9 Facial morphology (factor 19); LIHC cis rs2153535 0.580 rs1414345 chr6:8471537 T/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs2455799 0.634 rs11128765 chr3:15903331 G/T cg12698662 chr3:15914712 MIR563 -0.4 -7.35 -0.37 1.5e-12 Mean platelet volume; LIHC trans rs1814175 0.645 rs11040535 chr11:49808669 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -19.81 -0.73 1e-58 Height; LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg14671364 chr1:107599128 PRMT6 0.53 7.92 0.39 3.28e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7523273 0.606 rs2488254 chr1:207941539 A/G cg22525895 chr1:207977042 MIR29B2 0.65 10.36 0.49 4.83e-22 Schizophrenia; LIHC cis rs6466055 0.748 rs6962856 chr7:104953466 A/T cg04380332 chr7:105027541 SRPK2 -0.38 -7.13 -0.36 5.85e-12 Schizophrenia; LIHC cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08677755 chr19:7604888 PNPLA6 0.46 6.45 0.33 3.79e-10 Pancreatic cancer; LIHC cis rs10911232 0.507 rs6664995 chr1:183017345 T/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.09e-22 Hypertriglyceridemia; LIHC cis rs8016947 0.583 rs7140505 chr14:35830213 C/G cg03549618 chr14:35838977 NA 0.44 6.98 0.35 1.54e-11 Psoriasis; LIHC trans rs208520 1.000 rs72882079 chr6:66973878 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 6.93 0.35 2.06e-11 Exhaled nitric oxide output; LIHC cis rs3806843 0.966 rs3756338 chr5:140180561 A/G cg26395211 chr5:140044315 WDR55 -0.41 -6.04 -0.31 4.1e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9296092 0.517 rs11752179 chr6:33534713 G/T cg13560919 chr6:33536144 NA -0.4 -6.57 -0.33 1.92e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs561341 0.830 rs2301765 chr17:30202056 T/A cg13647721 chr17:30228624 UTP6 -0.74 -7.1 -0.36 7.45e-12 Hip circumference adjusted for BMI; LIHC cis rs1215050 0.791 rs1215049 chr4:98848280 C/T cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.92e-8 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs911555 0.692 rs7146215 chr14:103915908 A/G cg17675199 chr6:35436792 RPL10A -0.45 -9.34 -0.45 1.24e-18 Intelligence (multi-trait analysis); LIHC cis rs798554 0.660 rs798480 chr7:2805597 G/T cg19717773 chr7:2847554 GNA12 -0.4 -7.15 -0.36 5.44e-12 Height; LIHC cis rs6500602 0.702 rs2304634 chr16:4500544 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.47 6.71 0.34 8.23e-11 Schizophrenia; LIHC cis rs6665290 0.901 rs12410103 chr1:227197408 T/C cg10327440 chr1:227177885 CDC42BPA -1.19 -25.41 -0.81 8.99e-81 Myeloid white cell count; LIHC cis rs700651 0.789 rs10184395 chr2:198894285 G/A cg03934865 chr2:198174659 NA 0.43 6.19 0.32 1.74e-9 Intracranial aneurysm; LIHC cis rs72634258 0.554 rs12092614 chr1:7865710 C/T cg00864860 chr1:7907996 UTS2 0.57 5.72 0.3 2.39e-8 Inflammatory bowel disease; LIHC cis rs11190604 0.943 rs11190581 chr10:102243387 T/G cg07080220 chr10:102295463 HIF1AN 0.5 7.08 0.36 8.02e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg17554472 chr22:41940697 POLR3H 0.55 6.33 0.32 7.79e-10 Vitiligo; LIHC cis rs798554 0.759 rs1636255 chr7:2892804 A/C cg13628971 chr7:2884303 GNA12 -0.59 -9.93 -0.47 1.39e-20 Height; LIHC cis rs9359856 0.564 rs11961752 chr6:90481896 T/C cg13799429 chr6:90582589 CASP8AP2 -0.66 -5.86 -0.3 1.11e-8 Bipolar disorder; LIHC cis rs6061231 0.958 rs2427305 chr20:60953749 G/C cg24112000 chr20:60950667 NA -0.6 -8.34 -0.41 1.78e-15 Colorectal cancer; LIHC trans rs2352908 0.786 rs2000013 chr14:49442395 C/T cg16568472 chr20:3190600 ITPA -0.44 -6.04 -0.31 4.05e-9 Social communication problems; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg14476630 chr11:72437731 ARAP1 0.43 6.07 0.31 3.44e-9 Hip circumference; LIHC cis rs3859192 0.561 rs12453343 chr17:38181176 C/A cg17467752 chr17:38218738 THRA -0.53 -9.28 -0.45 1.98e-18 White blood cell count; LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg03785755 chr6:26196794 NA 0.51 5.97 0.31 5.8e-9 Gout;Renal underexcretion gout; LIHC cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg03517284 chr6:25882590 NA -0.6 -7.44 -0.37 8.31e-13 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.553 rs3907576 chr11:49536639 A/C cg18944383 chr4:111397179 ENPEP 0.25 6.2 0.32 1.6e-9 Coronary artery disease; LIHC cis rs2576037 0.561 rs513775 chr18:44396334 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 11.03 0.51 2.09e-24 Personality dimensions; LIHC cis rs1865760 0.566 rs2051544 chr6:26071093 C/T cg18357526 chr6:26021779 HIST1H4A 0.45 6.59 0.34 1.68e-10 Height; LIHC cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg01788221 chr16:89496183 ANKRD11 -0.41 -6.33 -0.32 7.89e-10 Multiple myeloma (IgH translocation); LIHC cis rs939574 0.586 rs3731892 chr2:220136351 G/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.85 5.72 0.3 2.33e-8 Platelet distribution width; LIHC trans rs7246657 1.000 rs35398388 chr19:37740358 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.19 0.32 1.7e-9 Coronary artery calcification; LIHC cis rs655641 1.000 rs618679 chr11:85671702 A/C cg09030501 chr11:85779252 PICALM -0.49 -5.78 -0.3 1.68e-8 Platelet count; LIHC cis rs9814567 1.000 rs2370642 chr3:134222136 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.86 -0.3 1.06e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs769267 0.895 rs2315279 chr19:19479936 C/A cg03709012 chr19:19516395 GATAD2A -1.01 -18.1 -0.7 7.56e-52 Tonsillectomy; LIHC cis rs2404602 0.692 rs2304920 chr15:76993867 T/C cg23625390 chr15:77176239 SCAPER 0.35 5.84 0.3 1.19e-8 Blood metabolite levels; LIHC cis rs1401999 0.934 rs1132776 chr3:183696402 A/G cg01324343 chr3:183735012 ABCC5 0.76 12.89 0.57 2.9e-31 Anterior chamber depth; LIHC cis rs7918232 0.941 rs1753413 chr10:27397112 T/C cg14240646 chr10:27532245 ACBD5 -0.69 -6.41 -0.33 4.77e-10 Breast cancer; LIHC cis rs74181299 0.750 rs13421845 chr2:65336033 G/A cg05010058 chr2:65284262 CEP68 -0.39 -6.63 -0.34 1.33e-10 Pulse pressure; LIHC cis rs4474465 1.000 rs10899506 chr11:78168705 C/T cg02023728 chr11:77925099 USP35 0.35 6.29 0.32 9.61e-10 Alzheimer's disease (survival time); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16780771 chr16:81643766 CMIP -0.43 -6.07 -0.31 3.33e-9 Systolic blood pressure; LIHC cis rs12893668 0.703 rs2403197 chr14:104053764 C/T cg24130564 chr14:104152367 KLC1 -0.54 -8.65 -0.42 2e-16 Reticulocyte count; LIHC cis rs2842992 0.673 rs6930904 chr6:160217433 T/A cg11366901 chr6:160182831 ACAT2 0.93 15.35 0.64 7.91e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs2607426 0.681 rs2254326 chr19:41255889 G/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.56 -6.63 -0.34 1.29e-10 Blood protein levels; LIHC cis rs734999 0.505 rs10797438 chr1:2540262 C/T cg18854424 chr1:2615690 NA 0.33 7.42 0.37 9.44e-13 Ulcerative colitis; LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg14709524 chr16:89940631 TCF25 0.53 7.17 0.36 4.75e-12 Skin colour saturation; LIHC cis rs68170813 0.559 rs2299422 chr7:106959832 A/T cg02696742 chr7:106810147 HBP1 -0.51 -5.91 -0.3 8.15e-9 Coronary artery disease; LIHC cis rs17253792 0.822 rs17253723 chr14:56154015 A/G cg01858014 chr14:56050164 KTN1 -0.7 -7.27 -0.37 2.42e-12 Putamen volume; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg22903471 chr2:27725779 GCKR -0.48 -8.39 -0.41 1.27e-15 Total body bone mineral density; LIHC cis rs9457247 0.967 rs2015864 chr6:167381476 T/C cg23791538 chr6:167370224 RNASET2 0.67 11.63 0.53 1.44e-26 Crohn's disease; LIHC cis rs67311347 1.000 rs12638199 chr3:40475285 A/G cg13409248 chr3:40428643 ENTPD3 0.4 6.78 0.34 5.45e-11 Renal cell carcinoma; LIHC cis rs1059312 0.808 rs4482069 chr12:129294252 G/C cg09035930 chr12:129282057 SLC15A4 0.6 11.22 0.52 4.42e-25 Systemic lupus erythematosus; LIHC cis rs2842992 0.830 rs2758320 chr6:160070676 T/G cg19482086 chr6:160211437 TCP1;MRPL18 0.69 11.36 0.52 1.33e-25 Age-related macular degeneration (geographic atrophy); LIHC cis rs2576037 0.523 rs1539881 chr18:44477897 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -7.19 -0.36 4.23e-12 Personality dimensions; LIHC trans rs11039798 1.000 rs11039904 chr11:48682597 T/A cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs903552 0.866 rs11247296 chr15:102007919 T/C cg16179521 chr15:102009894 PCSK6 -0.42 -5.76 -0.3 1.91e-8 Diabetic kidney disease; LIHC cis rs17125944 0.615 rs12586707 chr14:53298277 A/G cg00686598 chr14:53173677 PSMC6 -0.81 -9.54 -0.46 2.73e-19 Alzheimer's disease (late onset); LIHC cis rs778371 1.000 rs11535 chr2:233743532 G/C cg08000102 chr2:233561755 GIGYF2 -0.85 -13.54 -0.59 9.49e-34 Schizophrenia; LIHC cis rs68170813 0.559 rs76020313 chr7:106877468 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs13392177 0.672 rs4674270 chr2:219053141 G/T cg00012203 chr2:219082015 ARPC2 -0.73 -10.68 -0.5 3.72e-23 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg00656387 chr3:40428638 ENTPD3 0.5 8.29 0.41 2.68e-15 Renal cell carcinoma; LIHC cis rs9486715 0.929 rs7775721 chr6:97056979 C/T cg06623918 chr6:96969491 KIAA0776 -0.86 -14.45 -0.62 2.75e-37 Headache; LIHC cis rs2953174 0.744 rs2975748 chr2:241518989 A/G cg07929629 chr2:241523174 NA 0.59 6.88 0.35 2.84e-11 Bipolar disorder; LIHC cis rs6089584 1.000 rs6089584 chr20:60564086 G/C cg12751644 chr20:60527061 NA -0.36 -5.9 -0.3 8.53e-9 Body mass index; LIHC cis rs1023500 0.596 rs5758562 chr22:42448238 C/G cg15557168 chr22:42548783 NA -0.44 -6.87 -0.35 3.04e-11 Schizophrenia; LIHC cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg02931644 chr1:25747376 RHCE 0.34 7.4 0.37 1.09e-12 Erythrocyte sedimentation rate; LIHC cis rs8017423 0.765 rs8017170 chr14:90721849 T/A cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 2.97e-9 Mortality in heart failure; LIHC cis rs2288073 0.965 rs10173949 chr2:24410256 A/C cg06627628 chr2:24431161 ITSN2 -0.58 -7.63 -0.38 2.32e-13 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs7520050 0.966 rs10789487 chr1:46420221 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.42 6.24 0.32 1.3e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg11645453 chr3:52864694 ITIH4 0.21 5.76 0.3 1.85e-8 Bipolar disorder; LIHC cis rs61990749 0.544 rs1477259 chr14:78256138 C/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.63 -0.38 2.36e-13 Fibroblast growth factor basic levels; LIHC cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg12463550 chr7:65579703 CRCP 0.73 7.64 0.38 2.26e-13 Diabetic kidney disease; LIHC cis rs1506636 1.000 rs652497 chr7:123423671 G/T cg03229431 chr7:123269106 ASB15 0.6 11.85 0.54 2.27e-27 Plateletcrit;Platelet count; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC trans rs2243480 1.000 rs778704 chr7:65863467 T/C cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg05754148 chr16:3507555 NAT15 -0.39 -6.08 -0.31 3.15e-9 Tuberculosis; LIHC cis rs8180040 0.966 rs11130137 chr3:47578838 C/T cg16586182 chr3:47516702 SCAP -0.41 -7.37 -0.37 1.33e-12 Colorectal cancer; LIHC cis rs17539620 0.624 rs12665520 chr6:154835273 C/T cg20019720 chr6:154832845 CNKSR3 0.39 5.95 0.31 6.53e-9 Lipoprotein (a) levels; LIHC cis rs7918232 0.941 rs1753415 chr10:27395102 T/C cg14442939 chr10:27389572 ANKRD26 0.74 7.08 0.36 8.34e-12 Breast cancer; LIHC cis rs17854409 0.881 rs12625401 chr20:61472939 A/T cg05147244 chr20:61493195 TCFL5 1.23 11.01 0.51 2.37e-24 Obesity-related traits; LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg08280861 chr8:58055591 NA -0.55 -6.09 -0.31 3.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs11229555 0.645 rs4594017 chr11:58194788 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2250417 0.935 rs10891343 chr11:112080384 T/C cg07267984 chr11:112037134 TEX12 -0.41 -6.31 -0.32 8.7e-10 Inflammatory biomarkers;Protein quantitative trait loci; LIHC cis rs8103278 1.000 rs8108590 chr19:46301620 A/G cg14061069 chr19:46274453 DMPK -0.55 -8.58 -0.42 3.39e-16 Coronary artery disease; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg26338869 chr17:61819248 STRADA 0.52 6.97 0.35 1.61e-11 Height; LIHC cis rs6088813 1.000 rs6088815 chr20:33976474 G/C cg14752227 chr20:34000481 UQCC -0.4 -5.72 -0.3 2.39e-8 Height; LIHC cis rs8067545 0.611 rs2703805 chr17:20107773 T/C cg13482628 chr17:19912719 NA -0.42 -6.96 -0.35 1.74e-11 Schizophrenia; LIHC cis rs1577917 0.740 rs12212560 chr6:86342679 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.25 -0.32 1.21e-9 Response to antipsychotic treatment; LIHC cis rs4319547 0.656 rs4997380 chr12:122838956 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.34 -0.37 1.6e-12 Body mass index; LIHC cis rs3820068 0.705 rs72643701 chr1:15866219 G/A cg17385448 chr1:15911702 AGMAT 0.41 6.91 0.35 2.36e-11 Systolic blood pressure; LIHC cis rs919433 1.000 rs112572902 chr2:198175179 G/C cg10820045 chr2:198174542 NA -0.6 -10.31 -0.49 6.83e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs12477438 0.520 rs11123766 chr2:99780915 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.73 0.65 2.41e-42 Chronic sinus infection; LIHC trans rs3942852 0.774 rs10838811 chr11:48186795 A/G cg03929089 chr4:120376271 NA -0.56 -7.59 -0.38 3.09e-13 Acute lymphoblastic leukemia (childhood); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05492810 chr11:78129288 GAB2 0.43 6.09 0.31 3.01e-9 Lung function (FEV1/FVC); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg25005279 chr10:135113451 TUBGCP2 0.38 6.2 0.32 1.66e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs9916302 0.904 rs8081338 chr17:37406139 C/T cg07936489 chr17:37558343 FBXL20 -0.81 -12.95 -0.57 1.7e-31 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs778704 chr7:65863467 T/C cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs4555082 0.750 rs2816650 chr14:105708343 C/T cg10792982 chr14:105748885 BRF1 0.48 6.3 0.32 9.42e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs4423214 1.000 rs12808368 chr11:71170817 C/T cg24826892 chr11:71159390 DHCR7 0.48 6.16 0.32 1.99e-9 Vitamin D levels; LIHC cis rs317689 0.658 rs490872 chr12:69645864 A/G cg19645103 chr12:69753606 YEATS4 -0.45 -6.05 -0.31 3.7e-9 Response to diuretic therapy; LIHC cis rs743757 1.000 rs2236955 chr3:50429876 G/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.48 7.25 0.36 2.86e-12 Diastolic blood pressure; LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg00656387 chr3:40428638 ENTPD3 0.5 8.52 0.42 5.28e-16 Renal cell carcinoma; LIHC cis rs9916302 0.904 rs35285898 chr17:37555872 A/C cg03013999 chr17:37608204 MED1 -0.35 -5.81 -0.3 1.4e-8 Glomerular filtration rate (creatinine); LIHC cis rs9916302 0.861 rs11078912 chr17:37671490 A/G cg07936489 chr17:37558343 FBXL20 -0.82 -13.22 -0.58 1.58e-32 Glomerular filtration rate (creatinine); LIHC cis rs11785400 0.928 rs750529 chr8:143744877 G/C cg24634471 chr8:143751801 JRK 0.51 8.23 0.41 4.08e-15 Schizophrenia; LIHC cis rs4970988 0.556 rs6695123 chr1:150563483 T/C cg15448220 chr1:150897856 SETDB1 -0.42 -6.41 -0.33 4.83e-10 Urate levels; LIHC cis rs2760061 0.626 rs591582 chr1:228117360 C/A cg01200585 chr1:228362443 C1orf69 -0.4 -5.85 -0.3 1.16e-8 Diastolic blood pressure; LIHC cis rs7223966 1.000 rs56057198 chr17:61733332 G/A cg05941027 chr17:61774174 LIMD2 0.34 6.47 0.33 3.39e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7726839 0.540 rs72703095 chr5:601789 T/C cg09021430 chr5:549028 NA -0.42 -8.43 -0.41 9.770000000000001e-16 Obesity-related traits; LIHC cis rs9388451 0.874 rs1159974 chr6:126090277 C/T cg06289844 chr6:126071538 HEY2 -0.36 -6.27 -0.32 1.07e-9 Brugada syndrome; LIHC cis rs7772486 0.790 rs9399571 chr6:146282061 A/G cg13319975 chr6:146136371 FBXO30 0.36 5.84 0.3 1.21e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 0.713 rs73073505 chr3:40310693 C/T cg10755058 chr3:40428713 ENTPD3 0.36 5.79 0.3 1.57e-8 Renal cell carcinoma; LIHC cis rs7264396 0.635 rs6119672 chr20:34479767 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.58 -0.5 7.82e-23 Total cholesterol levels; LIHC cis rs7312933 0.670 rs10880258 chr12:42547531 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.81 0.39 6.87e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg18404041 chr3:52824283 ITIH1 -0.48 -7.74 -0.39 1.15e-13 Electroencephalogram traits; LIHC cis rs244293 1.000 rs2628314 chr17:53235182 T/C cg19360675 chr17:53046073 COX11;STXBP4 -0.43 -6.1 -0.31 2.82e-9 Menarche (age at onset); LIHC trans rs3780486 0.846 rs7036812 chr9:33143822 T/C cg04842962 chr6:43655489 MRPS18A 1.07 25.0 0.8 3.33e-79 IgG glycosylation; LIHC cis rs796364 0.806 rs6743396 chr2:200860138 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.79 8.64 0.42 2.16e-16 Schizophrenia; LIHC cis rs7216064 1.000 rs7221651 chr17:65832390 A/G cg12091567 chr17:66097778 LOC651250 0.64 9.6 0.46 1.83e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg26531700 chr6:26746687 NA -0.34 -5.77 -0.3 1.77e-8 Intelligence (multi-trait analysis); LIHC cis rs1144333 0.655 rs1361487 chr1:76430471 A/C cg03433033 chr1:76189801 ACADM 0.52 7.33 0.37 1.72e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs1448094 0.512 rs12313775 chr12:86241197 G/A cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC cis rs7917772 0.582 rs10786695 chr10:104368756 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.88 0.39 4.53e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3015497 0.789 rs2356457 chr14:51116863 C/T cg09863266 chr14:51125203 SAV1 -0.43 -7.04 -0.36 1.08e-11 Mean platelet volume; LIHC cis rs477895 1.000 rs41294396 chr11:64078581 G/A cg04317338 chr11:64019027 PLCB3 0.86 8.31 0.41 2.26e-15 Mean platelet volume; LIHC cis rs8053891 0.756 rs9928413 chr16:72001110 C/T cg01557791 chr16:72042693 DHODH -0.44 -6.24 -0.32 1.27e-9 Coronary artery disease; LIHC cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg11764359 chr7:65958608 NA 0.58 6.06 0.31 3.57e-9 Diabetic kidney disease; LIHC cis rs10911232 0.507 rs4596846 chr1:182976034 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Hypertriglyceridemia; LIHC cis rs11958404 0.932 rs76228149 chr5:157434486 G/A cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9367125 0.816 rs9357384 chr6:41997926 A/G cg12151296 chr6:42013349 CCND3 0.41 5.98 0.31 5.6e-9 Mean corpuscular hemoglobin; LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs3762637 0.882 rs56074178 chr3:122180011 C/G cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs11958404 1.000 rs72816527 chr5:157409633 C/T cg05962755 chr5:157440814 NA 1.05 11.42 0.53 8.24e-26 IgG glycosylation; LIHC cis rs3096299 0.933 rs3114848 chr16:89452771 G/A cg08392591 chr16:89556376 ANKRD11 0.39 5.91 0.3 8.29e-9 Multiple myeloma (IgH translocation); LIHC cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.35 0.41 1.71e-15 Platelet count; LIHC cis rs7089973 0.604 rs2420069 chr10:116605103 A/G cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2228479 0.717 rs11649210 chr16:89807233 C/G cg19635926 chr16:89946313 TCF25 0.44 5.78 0.3 1.66e-8 Skin colour saturation; LIHC cis rs8180040 0.966 rs6792488 chr3:47503349 C/T cg27129171 chr3:47204927 SETD2 -0.57 -9.76 -0.47 5.26e-20 Colorectal cancer; LIHC cis rs11122272 0.735 rs2486736 chr1:231521478 A/G cg06096015 chr1:231504339 EGLN1 -0.5 -9.42 -0.45 7.08e-19 Hemoglobin concentration; LIHC trans rs7668874 0.779 rs961954 chr4:116814751 T/A cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs6951245 0.935 rs11766669 chr7:1063593 C/T cg24642844 chr7:1081250 C7orf50 -0.89 -8.94 -0.44 2.52e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.72 12.48 0.56 1.05e-29 Colorectal cancer; LIHC cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg26818010 chr10:134567672 INPP5A 0.77 9.67 0.46 1.01e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1499614 0.522 rs13247442 chr7:66188858 T/C cg18252515 chr7:66147081 NA -1.37 -14.09 -0.61 7.21e-36 Gout; LIHC cis rs7845219 0.544 rs34293080 chr8:95908078 G/T cg13393036 chr8:95962371 TP53INP1 -0.33 -6.36 -0.33 6.53e-10 Type 2 diabetes; LIHC trans rs13113518 0.812 rs13116035 chr4:56427385 G/A cg15358633 chr12:38710606 ALG10B 0.44 6.27 0.32 1.07e-9 Height; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg01676552 chr8:146156633 ZNF16 0.4 6.13 0.31 2.46e-9 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs7223966 1.000 rs11658175 chr17:61923838 G/A cg05941027 chr17:61774174 LIMD2 0.35 7.29 0.37 2.18e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs929354 0.772 rs1182438 chr7:157027438 G/A cg05182265 chr7:156933206 UBE3C 0.32 6.0 0.31 5.14e-9 Body mass index; LIHC cis rs9733 0.650 rs1971378 chr1:150597261 C/T cg17724175 chr1:150552817 MCL1 -0.37 -7.58 -0.38 3.29e-13 Tonsillectomy; LIHC cis rs7255374 0.566 rs7255904 chr19:41529020 C/T cg27089200 chr19:41531976 NA 0.37 6.35 0.32 6.72e-10 DDT metabolite (p,p'-DDE levels); LIHC cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg06634786 chr22:41940651 POLR3H 0.82 8.99 0.44 1.71e-17 Vitiligo; LIHC cis rs6960043 0.818 rs2358158 chr7:15054063 T/C cg19272540 chr7:15055459 NA 0.26 7.0 0.35 1.34e-11 Type 2 diabetes; LIHC cis rs6121246 0.529 rs2889528 chr20:30210021 C/T cg13852791 chr20:30311386 BCL2L1 0.78 6.77 0.34 5.69e-11 Mean corpuscular hemoglobin; LIHC cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg23205692 chr1:25664452 TMEM50A 0.39 6.34 0.32 7.48e-10 Erythrocyte sedimentation rate; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.13 -0.31 2.47e-9 Total body bone mineral density; LIHC cis rs11958404 0.932 rs72818104 chr5:157437632 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs7618915 0.781 rs12489732 chr3:52566820 C/A cg17372223 chr3:52568218 NT5DC2 0.38 5.84 0.3 1.21e-8 Bipolar disorder; LIHC cis rs7937890 0.559 rs2597187 chr11:14517019 C/G cg02886208 chr11:14281011 SPON1 -0.43 -6.09 -0.31 3.04e-9 Mitochondrial DNA levels; LIHC cis rs60871478 1.000 rs12531530 chr7:827366 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.53 6.11 0.31 2.72e-9 Cerebrospinal P-tau181p levels; LIHC cis rs1034435 0.755 rs5768680 chr22:48892919 T/C cg05992904 chr22:48892994 FAM19A5 -0.53 -10.87 -0.51 7.65e-24 Late-onset Alzheimer's disease; LIHC cis rs1580019 0.587 rs7804457 chr7:32557981 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.14 26.46 0.82 9.25e-85 Cognitive ability; LIHC cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg25072359 chr17:41440525 NA 0.39 6.2 0.32 1.58e-9 Menopause (age at onset); LIHC cis rs1215050 0.904 rs9307215 chr4:98813965 A/G cg05340658 chr4:99064831 C4orf37 0.44 6.02 0.31 4.43e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs249954 0.512 rs249870 chr16:23666178 C/A cg05131483 chr16:23706242 ERN2 0.38 6.3 0.32 8.91e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 7.91 0.39 3.52e-14 Height; LIHC cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg12310025 chr6:25882481 NA -1.1 -17.57 -0.69 1.08e-49 Urate levels; LIHC cis rs7618501 0.633 rs6772095 chr3:49978069 C/T cg21467203 chr3:49911342 NA -0.44 -7.91 -0.39 3.57e-14 Intelligence (multi-trait analysis); LIHC cis rs644799 1.000 rs596277 chr11:95566886 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.49 0.46 4.04e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2732480 0.500 rs1387257 chr12:48636666 C/A cg21466736 chr12:48725269 NA -0.71 -10.87 -0.51 7.92e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg19635926 chr16:89946313 TCF25 0.54 7.33 0.37 1.65e-12 Skin colour saturation; LIHC cis rs7208859 0.623 rs76633166 chr17:29113365 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs708547 0.581 rs13121027 chr4:57813369 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.5 -7.34 -0.37 1.61e-12 Response to bleomycin (chromatid breaks); LIHC trans rs1814175 0.676 rs1851859 chr11:49860405 A/T cg03929089 chr4:120376271 NA -0.83 -15.82 -0.65 1.12e-42 Height; LIHC cis rs12701220 0.894 rs12701348 chr7:1039457 C/T cg26769984 chr7:1090371 C7orf50 0.54 6.99 0.35 1.48e-11 Bronchopulmonary dysplasia; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.817 rs10839465 chr11:49981554 C/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs35892873 0.959 rs756182 chr3:126093885 C/T cg15490784 chr3:126061950 KLF15 0.42 5.95 0.31 6.51e-9 Male-pattern baldness; LIHC cis rs1267303 0.642 rs7542296 chr1:46998009 A/G cg25110126 chr1:46999211 NA 0.46 6.68 0.34 9.83e-11 Monobrow; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25396690 chr2:7006004 CMPK2 -0.55 -6.88 -0.35 2.88e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs11711311 1.000 rs2305545 chr3:113499733 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.95 -0.35 1.88e-11 IgG glycosylation; LIHC cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg12756686 chr19:29218302 NA 0.43 6.43 0.33 4.37e-10 Methadone dose in opioid dependence; LIHC cis rs11098499 0.865 rs4507344 chr4:120307485 C/A cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs7715806 0.500 rs4703676 chr5:74979866 G/C cg19683494 chr5:74908142 NA 0.69 7.91 0.39 3.57e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs66573146 1.000 rs56074877 chr4:6990374 C/T cg07817883 chr1:32538562 TMEM39B 1.17 9.34 0.45 1.3e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs911119 0.913 rs1158167 chr20:23578189 G/A cg16589663 chr20:23618590 CST3 -0.69 -7.29 -0.37 2.21e-12 Chronic kidney disease; LIHC cis rs2072499 0.966 rs887953 chr1:156191149 T/C cg25208724 chr1:156163844 SLC25A44 0.9 15.13 0.63 6.16e-40 Testicular germ cell tumor; LIHC cis rs13064411 0.696 rs7613546 chr3:113228019 G/A cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs712039 0.583 rs853223 chr17:35791149 T/C cg16670864 chr17:35848621 DUSP14 0.33 5.71 0.3 2.4e-8 Tuberculosis; LIHC cis rs9522267 0.535 rs9522304 chr13:112237316 C/T cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs2033711 0.870 rs4801270 chr19:58932762 C/A cg00825309 chr19:58991885 ZNF446 -0.63 -9.78 -0.47 4.29e-20 Uric acid clearance; LIHC cis rs12808519 0.605 rs3893155 chr11:69597881 T/C cg19831575 chr11:69590090 FGF4 0.51 6.88 0.35 2.82e-11 Urate levels in overweight individuals; LIHC cis rs611744 0.967 rs662714 chr8:109221659 C/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.32e-16 Dupuytren's disease; LIHC cis rs6831352 0.918 rs2851247 chr4:100046091 C/G cg12011299 chr4:100065546 ADH4 -0.64 -10.4 -0.49 3.41e-22 Alcohol dependence; LIHC cis rs35110281 0.774 rs2838323 chr21:44999086 G/A cg01579765 chr21:45077557 HSF2BP -0.35 -6.58 -0.34 1.72e-10 Mean corpuscular volume; LIHC cis rs11122272 0.735 rs2790889 chr1:231520240 C/A cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs7103648 0.669 rs11039332 chr11:47695840 G/A cg20307385 chr11:47447363 PSMC3 0.99 16.22 0.66 2.8e-44 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.8 15.3 0.64 1.28e-40 Prudent dietary pattern; LIHC cis rs11605275 1.000 rs78091560 chr11:20032279 G/A cg14835545 chr11:20032148 NAV2 -0.8 -7.38 -0.37 1.18e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2073300 1.000 rs74273799 chr20:23444492 T/C cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20303232 chr11:114270563 C11orf71;RBM7 0.46 6.64 0.34 1.27e-10 Cognitive function; LIHC trans rs61931739 0.534 rs11053014 chr12:34103519 G/A cg26384229 chr12:38710491 ALG10B 0.53 7.33 0.37 1.64e-12 Morning vs. evening chronotype; LIHC cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg13395646 chr4:1353034 KIAA1530 0.42 6.57 0.33 1.83e-10 Obesity-related traits; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg00147976 chr12:53846229 PCBP2 0.4 6.16 0.32 2.04e-9 Migraine with aura; LIHC cis rs1816752 0.805 rs4769353 chr13:25000456 A/G cg02811702 chr13:24901961 NA 0.24 6.01 0.31 4.69e-9 Obesity-related traits; LIHC trans rs9914544 0.545 rs8073436 chr17:18801841 A/G cg21372672 chr17:16614065 CCDC144A -0.26 -6.41 -0.33 4.84e-10 Educational attainment (years of education); LIHC cis rs875971 0.862 rs10282433 chr7:65721439 G/A cg18876405 chr7:65276391 NA -0.35 -6.32 -0.32 7.96e-10 Aortic root size; LIHC cis rs57590327 0.716 rs56106807 chr3:81765270 A/G cg07356753 chr3:81810745 GBE1 -0.53 -7.65 -0.38 2.07e-13 Extraversion; LIHC cis rs1865760 0.566 rs1539183 chr6:26075051 G/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23324888 chr5:111093475 C5orf13 -0.45 -6.08 -0.31 3.15e-9 Systolic blood pressure; LIHC cis rs2286885 1.000 rs10760438 chr9:129245334 C/A cg15282417 chr9:129245246 FAM125B 0.4 6.45 0.33 3.77e-10 Intraocular pressure; LIHC trans rs11098499 0.866 rs7677068 chr4:120291704 C/T cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs9648428 1.000 rs9648428 chr7:36211749 C/T cg14708893 chr7:36124863 NA -0.51 -6.08 -0.31 3.13e-9 Obesity-related traits; LIHC cis rs17270561 0.609 rs1165155 chr6:25795577 A/T cg17691542 chr6:26056736 HIST1H1C 0.44 6.01 0.31 4.75e-9 Iron status biomarkers; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10883266 chr13:100741297 PCCA -0.45 -6.39 -0.33 5.49e-10 Systolic blood pressure; LIHC cis rs950776 0.518 rs62008174 chr15:78808947 C/T cg22563815 chr15:78856949 CHRNA5 0.35 6.19 0.32 1.77e-9 Sudden cardiac arrest; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25437947 chr8:17941982 ASAH1 -0.54 -6.18 -0.32 1.83e-9 Systolic blood pressure; LIHC cis rs6456156 0.792 rs7775443 chr6:167513252 A/C cg07741184 chr6:167504864 NA -0.28 -6.88 -0.35 2.84e-11 Primary biliary cholangitis; LIHC cis rs16828019 0.852 rs12759023 chr1:41603978 T/C cg03387723 chr1:41708464 SCMH1 -0.45 -7.22 -0.36 3.37e-12 Intelligence (multi-trait analysis); LIHC cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg14983838 chr19:29218262 NA 0.5 7.48 0.37 6.37e-13 Methadone dose in opioid dependence; LIHC cis rs4713118 0.547 rs2116981 chr6:28067951 T/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Parkinson's disease; LIHC cis rs2439831 0.764 rs12324584 chr15:43683446 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.73 10.54 0.5 1.15e-22 Lung cancer in ever smokers; LIHC cis rs10751667 0.666 rs6597957 chr11:982294 T/A ch.11.42038R chr11:967971 AP2A2 0.55 9.85 0.47 2.58e-20 Alzheimer's disease (late onset); LIHC cis rs74181299 0.533 rs6751786 chr2:65374595 G/T cg05010058 chr2:65284262 CEP68 -0.36 -5.8 -0.3 1.53e-8 Pulse pressure; LIHC cis rs9814567 1.000 rs4955485 chr3:134295843 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.26 -0.32 1.13e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg20295408 chr7:1910781 MAD1L1 0.41 6.13 0.31 2.38e-9 Bipolar disorder and schizophrenia; LIHC cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg23172400 chr8:95962367 TP53INP1 -0.36 -7.58 -0.38 3.33e-13 Type 2 diabetes; LIHC cis rs7707921 0.723 rs226203 chr5:81570394 G/A cg15871215 chr5:81402204 ATG10 0.65 7.63 0.38 2.31e-13 Breast cancer; LIHC cis rs2404602 0.647 rs4886840 chr15:77179002 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.61 -0.46 1.69e-19 Blood metabolite levels; LIHC cis rs758324 0.947 rs2088719 chr5:131184439 C/T cg06307176 chr5:131281290 NA 0.4 5.74 0.3 2.12e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg11494091 chr17:61959527 GH2 0.44 8.19 0.4 5.24e-15 Prudent dietary pattern; LIHC cis rs7945705 0.905 rs2568054 chr11:8876029 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.53 -9.53 -0.46 3.01e-19 Hemoglobin concentration; LIHC cis rs5769707 0.632 rs135876 chr22:50013573 A/G cg01652190 chr22:50026171 C22orf34 -0.33 -7.3 -0.37 1.98e-12 Monocyte count;Monocyte percentage of white cells; LIHC trans rs3743102 0.519 rs76496098 chr15:83229141 T/C cg01542190 chr22:50604728 NA -0.51 -6.56 -0.33 2.01e-10 Colorectal adenoma (advanced); LIHC trans rs8073060 0.586 rs225303 chr17:33922149 A/G cg19694781 chr19:47549865 TMEM160 1.15 12.58 0.56 4.39e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6918586 0.658 rs198821 chr6:26123629 T/C cg18357526 chr6:26021779 HIST1H4A -0.59 -8.88 -0.43 3.85e-17 Schizophrenia; LIHC cis rs11955398 0.625 rs6874072 chr5:59987682 C/G cg02684056 chr5:59996105 DEPDC1B 0.44 6.23 0.32 1.36e-9 Intelligence (multi-trait analysis); LIHC cis rs16958440 1.000 rs16952848 chr18:44597829 A/G cg17192377 chr18:44677553 HDHD2 0.57 6.11 0.31 2.68e-9 Sitting height ratio; LIHC cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.25 -0.45 2.55e-18 Bipolar disorder; LIHC cis rs6570726 0.935 rs454614 chr6:145832633 C/T cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2404602 0.647 rs35710279 chr15:77082234 T/A cg23625390 chr15:77176239 SCAPER -0.53 -8.82 -0.43 5.86e-17 Blood metabolite levels; LIHC cis rs317689 0.581 rs315132 chr12:69761996 G/C cg19645103 chr12:69753606 YEATS4 -0.52 -7.83 -0.39 6.3e-14 Response to diuretic therapy; LIHC cis rs17401966 1.000 rs12130220 chr1:10359944 T/G cg15208524 chr1:10270712 KIF1B 0.45 6.6 0.34 1.55e-10 Hepatocellular carcinoma; LIHC cis rs6951245 0.935 rs11763765 chr7:1060510 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -6.02 -0.31 4.58e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8044995 0.501 rs7189887 chr16:68353915 C/T cg03983715 chr16:68378420 PRMT7 -0.53 -6.16 -0.32 1.99e-9 Schizophrenia; LIHC cis rs9902453 1.000 rs4575590 chr17:28361969 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05508062 chr3:62110348 ID2B;PTPRG 0.44 6.34 0.32 7.12e-10 Pancreatic cancer; LIHC cis rs875971 0.862 rs801195 chr7:66026115 A/G cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.22e-34 Aortic root size; LIHC cis rs738322 0.555 rs6001029 chr22:38555193 C/A cg25457927 chr22:38595422 NA -0.39 -9.52 -0.46 3.28e-19 Cutaneous nevi; LIHC cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg11861562 chr11:117069780 TAGLN -0.47 -7.66 -0.38 1.94e-13 Blood protein levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07294177 chr3:160283371 KPNA4 -0.53 -6.5 -0.33 2.79e-10 Systolic blood pressure; LIHC cis rs10791097 0.694 rs2155750 chr11:130751261 A/C cg09137382 chr11:130731461 NA 0.42 6.26 0.32 1.18e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg04267008 chr7:1944627 MAD1L1 -0.58 -8.96 -0.44 2.07e-17 Bipolar disorder and schizophrenia; LIHC trans rs11098499 0.954 rs3733520 chr4:120423480 C/G cg25214090 chr10:38739885 LOC399744 0.57 9.27 0.45 2.21e-18 Corneal astigmatism; LIHC cis rs10197940 0.662 rs1047957 chr2:152333773 C/T cg06191203 chr2:152266755 RIF1 -0.44 -7.58 -0.38 3.27e-13 Lung cancer; LIHC cis rs240764 0.782 rs239222 chr6:101112817 T/A cg09795085 chr6:101329169 ASCC3 0.5 7.05 0.36 1.02e-11 Neuroticism; LIHC cis rs4148883 0.628 rs34195655 chr4:100073795 C/T cg12011299 chr4:100065546 ADH4 0.37 7.27 0.37 2.51e-12 Alcohol dependence; LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg09455208 chr3:40491958 NA 0.4 8.24 0.41 3.63e-15 Renal cell carcinoma; LIHC cis rs7618501 0.602 rs2526754 chr3:50125996 G/A cg21467203 chr3:49911342 NA 0.44 7.76 0.39 1.01e-13 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.7 11.71 0.54 7.11e-27 Prudent dietary pattern; LIHC cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg06108461 chr20:60628389 TAF4 -0.9 -13.96 -0.6 2.3e-35 Body mass index; LIHC cis rs2836974 0.644 rs2836986 chr21:40702136 A/C cg06238570 chr21:40685208 BRWD1 -0.52 -8.58 -0.42 3.44e-16 Cognitive function; LIHC cis rs2635047 1.000 rs2684841 chr18:44724262 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.49 6.65 0.34 1.13e-10 Educational attainment; LIHC cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg17971929 chr21:40555470 PSMG1 0.87 10.35 0.49 4.91e-22 Cognitive function; LIHC cis rs4927850 1.000 rs7630875 chr3:195753766 A/G cg12923728 chr3:195709715 SDHAP1 -0.74 -10.57 -0.5 8.59e-23 Pancreatic cancer; LIHC cis rs2404602 0.532 rs744336 chr15:76674624 T/C cg23625390 chr15:77176239 SCAPER 0.4 6.68 0.34 9.83e-11 Blood metabolite levels; LIHC trans rs941408 1.000 rs2260416 chr19:2796355 G/A cg19676328 chr12:49525230 TUBA1B -0.37 -6.13 -0.31 2.39e-9 Total cholesterol levels; LIHC cis rs12594515 1.000 rs8031128 chr15:45988528 C/G cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.8e-12 Waist circumference;Weight; LIHC cis rs9309473 0.607 rs7573719 chr2:73582986 G/A cg20560298 chr2:73613845 ALMS1 -0.44 -7.0 -0.35 1.39e-11 Metabolite levels; LIHC cis rs4073582 0.595 rs1151540 chr11:66041807 A/C cg16950941 chr11:66035639 RAB1B 0.61 9.11 0.44 7.27e-18 Gout; LIHC cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg21448741 chr8:58168803 NA 0.35 6.55 0.33 2.1e-10 Developmental language disorder (linguistic errors); LIHC cis rs28374715 0.578 rs8036026 chr15:41630499 C/G cg18705301 chr15:41695430 NDUFAF1 -1.21 -16.78 -0.67 1.55e-46 Ulcerative colitis; LIHC cis rs7605378 0.528 rs281787 chr2:200784238 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.53 -6.95 -0.35 1.85e-11 Osteoporosis; LIHC cis rs831571 1.000 rs831571 chr3:64048297 A/G cg16258503 chr3:63850278 ATXN7;THOC7 0.52 6.49 0.33 2.94e-10 Type 2 diabetes; LIHC cis rs6545883 0.929 rs12612982 chr2:61747355 G/A cg15711740 chr2:61764176 XPO1 -0.44 -6.24 -0.32 1.27e-9 Tuberculosis; LIHC cis rs9303401 0.614 rs12950028 chr17:56510140 A/G cg25039879 chr17:56429692 SUPT4H1 0.77 8.74 0.43 1.05e-16 Cognitive test performance; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs12594515 0.967 rs11070465 chr15:45984899 A/G cg06207120 chr15:45996521 NA 0.33 6.44 0.33 4.12e-10 Waist circumference;Weight; LIHC cis rs2991971 0.810 rs2036021 chr1:45901370 G/A cg15605315 chr1:45957053 TESK2 0.48 6.72 0.34 7.49e-11 High light scatter reticulocyte count; LIHC cis rs8077889 0.672 rs15359 chr17:41843979 C/G cg26893861 chr17:41843967 DUSP3 -1.14 -21.7 -0.76 2.95e-66 Triglycerides; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.11 0.55 2.37e-28 Prudent dietary pattern; LIHC cis rs3806843 1.000 rs2240694 chr5:140183058 G/A cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.65e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg09455208 chr3:40491958 NA 0.34 6.97 0.35 1.64e-11 Renal cell carcinoma; LIHC cis rs9325144 0.624 rs12231544 chr12:38901956 C/T cg26384229 chr12:38710491 ALG10B -0.55 -7.55 -0.38 4.1e-13 Morning vs. evening chronotype; LIHC cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.68 -0.5 3.48e-23 Alzheimer's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09655191 chr17:73915849 FBF1 0.44 6.84 0.35 3.63e-11 Longevity; LIHC cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg05564831 chr3:52568323 NT5DC2 0.38 6.05 0.31 3.78e-9 Bipolar disorder; LIHC cis rs10857712 0.754 rs2297032 chr10:135234580 C/T cg17796960 chr10:135278976 LOC619207 -0.35 -5.79 -0.3 1.61e-8 Systemic lupus erythematosus; LIHC cis rs9640161 0.830 rs3757424 chr7:150067679 C/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -8.19 -0.41 5.1e-15 Blood protein levels;Circulating chemerin levels; LIHC trans rs728616 0.681 rs12769764 chr10:81917113 C/G cg06341202 chr17:78010343 CCDC40;TBC1D16 0.45 6.19 0.32 1.71e-9 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs9291683 0.618 rs13137343 chr4:10043028 C/A cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.78e-13 Bone mineral density; LIHC cis rs7312933 0.703 rs10459290 chr12:42613290 T/G cg17420585 chr12:42539391 GXYLT1 -0.39 -6.33 -0.32 7.92e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2257205 0.667 rs8081074 chr17:56836596 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -6.61 -0.34 1.5e-10 Pancreatic cancer; LIHC cis rs748404 0.516 rs523156 chr15:43811843 C/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.4 -5.95 -0.31 6.49e-9 Lung cancer; LIHC cis rs7715806 0.500 rs34355 chr5:74959970 G/A cg19683494 chr5:74908142 NA -0.82 -10.49 -0.49 1.62e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4650994 0.593 rs16853043 chr1:178545926 A/G cg05350800 chr1:178550844 NA -0.34 -7.26 -0.37 2.56e-12 HDL cholesterol levels;HDL cholesterol; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06734816 chr6:116422381 NT5DC1 0.45 6.13 0.31 2.39e-9 Pancreatic cancer; LIHC cis rs8180040 0.932 rs11711265 chr3:47558448 T/C cg16586182 chr3:47516702 SCAP -0.43 -7.51 -0.38 5.16e-13 Colorectal cancer; LIHC cis rs875971 0.862 rs6959268 chr7:65812966 G/A cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs372883 0.564 rs766928 chr21:30753606 A/G cg24692254 chr21:30365293 RNF160 0.48 5.94 0.31 6.98e-9 Pancreatic cancer; LIHC cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.38 0.45 9.63e-19 Bipolar disorder; LIHC cis rs116095464 0.558 rs9687898 chr5:253952 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs1005277 0.579 rs1740735 chr10:38497777 A/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.28 -0.32 1e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3784262 0.904 rs4646620 chr15:58258241 G/A cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.53 -0.33 2.4e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs1707322 1.000 rs10789485 chr1:46407308 C/T cg03146154 chr1:46216737 IPP 0.48 7.74 0.39 1.1e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg12334488 chr2:20871173 GDF7 -0.47 -8.98 -0.44 1.89e-17 Abdominal aortic aneurysm; LIHC cis rs1577917 0.958 rs11756615 chr6:86679835 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.82 -0.35 4.05e-11 Response to antipsychotic treatment; LIHC cis rs4555082 0.957 rs2816609 chr14:105720803 A/C cg06808227 chr14:105710500 BRF1 -0.54 -7.09 -0.36 7.57e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs5769765 1.000 rs2295409 chr22:50261060 G/C cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.06 0.44 1.05e-17 Schizophrenia; LIHC cis rs10751667 0.666 rs7103585 chr11:971166 T/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC trans rs17685 0.753 rs2108274 chr7:75781636 C/A cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9902453 0.904 rs4461132 chr17:28423430 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 10.89 0.51 6.6e-24 Coffee consumption (cups per day); LIHC cis rs1348850 0.526 rs2293475 chr2:178407897 C/T cg27490568 chr2:178487706 NA -0.83 -9.2 -0.45 3.56e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9733 0.525 rs11584184 chr1:150695689 A/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs1419980 0.730 rs115594156 chr12:7751337 A/G cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs2404602 0.552 rs4886823 chr15:76965402 A/G cg23625390 chr15:77176239 SCAPER -0.47 -7.65 -0.38 2.02e-13 Blood metabolite levels; LIHC trans rs9858542 0.953 rs9862080 chr3:49674458 A/G cg21659725 chr3:3221576 CRBN -0.59 -6.61 -0.34 1.5e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2274273 0.870 rs946059 chr14:55847466 A/G cg01864836 chr14:55583639 NA -0.41 -7.61 -0.38 2.65e-13 Protein biomarker; LIHC trans rs3780486 1.000 rs10813957 chr9:33153527 G/T cg04842962 chr6:43655489 MRPS18A 0.95 16.87 0.67 7.2e-47 IgG glycosylation; LIHC cis rs77106637 0.932 rs17244499 chr11:72629946 C/T cg03713592 chr11:72463424 ARAP1 -0.82 -7.39 -0.37 1.17e-12 Type 2 diabetes; LIHC trans rs6489882 0.966 rs6489880 chr12:113380271 C/T cg10175203 chr3:128143634 NA 0.39 6.23 0.32 1.37e-9 Chronic lymphocytic leukemia; LIHC cis rs13161895 0.702 rs73810942 chr5:179499267 C/A cg02702477 chr5:179499311 RNF130 1.0 12.72 0.57 1.27e-30 LDL cholesterol; LIHC cis rs6500602 0.727 rs4786516 chr16:4578641 C/T cg08645402 chr16:4508243 NA 0.43 8.2 0.41 4.79e-15 Schizophrenia; LIHC cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg06640241 chr16:89574553 SPG7 0.85 15.59 0.64 8.92e-42 Multiple myeloma (IgH translocation); LIHC cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg19318889 chr4:1322082 MAEA 0.41 5.73 0.3 2.17e-8 Obesity-related traits; LIHC cis rs208520 0.690 rs12192851 chr6:66705862 G/C cg07460842 chr6:66804631 NA 0.74 8.61 0.42 2.8e-16 Exhaled nitric oxide output; LIHC cis rs2066819 1.000 rs79750959 chr12:56702012 C/A cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs1005277 0.541 rs2263163 chr10:38389887 G/A cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg09904177 chr6:26538194 HMGN4 0.57 11.2 0.52 5.05e-25 Intelligence (multi-trait analysis); LIHC cis rs7917772 0.503 rs7068535 chr10:104349127 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.75 0.57 9.72e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17286411 0.750 rs4788568 chr16:71913025 C/T cg03805757 chr16:71968109 PKD1L3 0.41 5.85 0.3 1.13e-8 Blood protein levels; LIHC cis rs909002 0.789 rs2139539 chr1:32117779 C/T cg13919466 chr1:32135498 COL16A1 -0.36 -6.66 -0.34 1.1e-10 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.868 rs2531352 chr5:140119534 A/G cg26395211 chr5:140044315 WDR55 0.39 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9513627 1.000 rs3928271 chr13:100186958 G/A cg25919922 chr13:100150906 NA 0.76 6.88 0.35 2.85e-11 Obesity-related traits; LIHC cis rs7020830 0.931 rs13297576 chr9:37142189 A/C cg14294708 chr9:37120828 ZCCHC7 1.2 28.8 0.84 1.89e-93 Schizophrenia; LIHC cis rs7666738 0.830 rs60007031 chr4:98824753 G/C cg05340658 chr4:99064831 C4orf37 0.63 11.4 0.52 9.93e-26 Colonoscopy-negative controls vs population controls; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18230796 chr4:3294592 NA -0.56 -6.3 -0.32 9.39e-10 Systolic blood pressure; LIHC cis rs2060793 0.506 rs10741658 chr11:14924736 T/C cg00085434 chr11:14927489 NA 0.43 6.17 0.32 1.95e-9 Vitamin D levels; LIHC cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg13047869 chr3:10149882 C3orf24 0.5 6.11 0.31 2.71e-9 Alzheimer's disease; LIHC cis rs9300255 0.596 rs11057207 chr12:123730891 T/G cg00376283 chr12:123451042 ABCB9 0.69 10.45 0.49 2.36e-22 Neutrophil percentage of white cells; LIHC cis rs922107 0.934 rs12118131 chr1:90041187 T/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.77 -0.39 9.52e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs933688 1.000 rs4382199 chr5:90744228 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.97 19.44 0.72 3.22e-57 Smoking behavior; LIHC cis rs9309711 0.666 rs6723101 chr2:3484443 T/C cg04359351 chr2:3481828 TTC15 0.28 5.94 0.31 7.04e-9 Neurofibrillary tangles; LIHC cis rs2242116 0.796 rs4683297 chr3:46973673 T/C cg16586182 chr3:47516702 SCAP 0.39 6.68 0.34 9.73e-11 Birth weight; LIHC cis rs5769765 0.817 rs11912619 chr22:50317401 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.74 -9.26 -0.45 2.38e-18 Schizophrenia; LIHC cis rs778371 1.000 rs709937 chr2:233744021 A/G cg08000102 chr2:233561755 GIGYF2 0.86 13.44 0.59 2.26e-33 Schizophrenia; LIHC cis rs1577917 1.000 rs35760725 chr6:86648985 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.8 -0.39 7.72e-14 Response to antipsychotic treatment; LIHC cis rs9918079 0.560 rs7662032 chr4:15635414 C/G cg16509355 chr4:15471240 CC2D2A -0.45 -7.08 -0.36 8.31e-12 Obesity-related traits; LIHC cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg00149659 chr3:10157352 C3orf10 -0.61 -6.74 -0.34 6.6e-11 Alzheimer's disease; LIHC cis rs2408955 0.522 rs4760612 chr12:48421856 C/T cg21466736 chr12:48725269 NA 0.6 8.26 0.41 3.26e-15 Glycated hemoglobin levels; LIHC cis rs2242116 0.760 rs4682845 chr3:46955404 G/C cg27129171 chr3:47204927 SETD2 0.49 7.71 0.38 1.42e-13 Birth weight; LIHC cis rs986417 0.901 rs4640083 chr14:61097779 G/A cg27398547 chr14:60952738 C14orf39 0.65 6.51 0.33 2.69e-10 Gut microbiota (bacterial taxa); LIHC cis rs8072100 0.871 rs7206971 chr17:45425115 A/G cg25173405 chr17:45401733 C17orf57 0.44 6.12 0.31 2.49e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10540 0.915 rs35333170 chr11:526478 A/G cg03576123 chr11:487126 PTDSS2 -1.0 -7.1 -0.36 7.26e-12 Body mass index; LIHC cis rs7772486 0.686 rs6933161 chr6:146081369 G/A cg23711669 chr6:146136114 FBXO30 -0.65 -11.6 -0.53 1.8e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 0.850 rs2302162 chr16:89845287 A/G cg19635926 chr16:89946313 TCF25 0.52 6.57 0.33 1.88e-10 Skin colour saturation; LIHC cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg24549020 chr5:56110836 MAP3K1 0.49 6.24 0.32 1.3e-9 Initial pursuit acceleration; LIHC cis rs2274273 0.712 rs1002054 chr14:55528913 A/C cg01864836 chr14:55583639 NA -0.38 -6.49 -0.33 3e-10 Protein biomarker; LIHC cis rs17401966 0.838 rs2182326 chr1:10385664 G/A cg19773385 chr1:10388646 KIF1B -0.41 -7.34 -0.37 1.59e-12 Hepatocellular carcinoma; LIHC cis rs2549003 0.934 rs2549006 chr5:131827065 A/G cg02551604 chr5:131831745 NA 0.49 7.27 0.37 2.48e-12 Asthma (sex interaction); LIHC cis rs9790314 0.560 rs4856701 chr3:161044106 G/T cg03342759 chr3:160939853 NMD3 -0.44 -6.32 -0.32 8.28e-10 Morning vs. evening chronotype; LIHC cis rs10791097 0.694 rs7942621 chr11:130751308 C/G cg12179176 chr11:130786555 SNX19 0.81 12.86 0.57 3.98e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15072735 chr9:72375102 PTAR1 0.42 6.62 0.34 1.38e-10 Cognitive function; LIHC trans rs208520 0.565 rs1385222 chr6:66753013 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.84 15.16 0.63 4.42e-40 Exhaled nitric oxide output; LIHC cis rs2067615 0.524 rs754184 chr12:107117521 A/G cg15890332 chr12:107067104 RFX4 0.26 6.25 0.32 1.22e-9 Heart rate; LIHC cis rs929354 0.742 rs2051877 chr7:157008813 A/T cg16102536 chr7:156981717 UBE3C 0.37 6.16 0.32 2.05e-9 Body mass index; LIHC cis rs9303401 0.659 rs16943176 chr17:56769887 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg03874509 chr1:107600012 PRMT6 -0.73 -11.5 -0.53 4.4e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7980687 0.657 rs2851447 chr12:123665113 G/C cg05973401 chr12:123451056 ABCB9 0.45 6.21 0.32 1.56e-9 Height;Educational attainment;Head circumference (infant); LIHC cis rs701145 0.556 rs355756 chr3:154021063 G/A cg16511985 chr3:153974050 SGEF 0.42 8.87 0.43 4e-17 Coronary artery disease; LIHC cis rs7727544 0.709 rs441969 chr5:131702120 G/A cg07395648 chr5:131743802 NA -0.32 -6.59 -0.34 1.7e-10 Blood metabolite levels; LIHC cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg05025164 chr4:1340916 KIAA1530 0.76 11.77 0.54 4.28e-27 Longevity; LIHC cis rs7772486 0.790 rs2485632 chr6:146193228 A/G cg23711669 chr6:146136114 FBXO30 0.66 11.85 0.54 2.23e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs6964587 1.000 rs12530646 chr7:91588036 A/G cg17063962 chr7:91808500 NA -1.03 -19.56 -0.73 1.04e-57 Breast cancer; LIHC trans rs208520 1.000 rs12193164 chr6:66978962 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.04 0.36 1.04e-11 Exhaled nitric oxide output; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg24689585 chr15:22957012 CYFIP1 0.41 6.34 0.32 7.34e-10 Alopecia areata; LIHC cis rs17685 0.753 rs2286830 chr7:75693963 C/T cg04610667 chr7:75704037 NA 0.35 6.24 0.32 1.27e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7312774 0.618 rs61061573 chr12:107372758 T/C cg16260113 chr12:107380972 MTERFD3 0.97 12.34 0.56 3.48e-29 Severe influenza A (H1N1) infection; LIHC cis rs477895 0.713 rs11607165 chr11:63963947 T/G cg18225595 chr11:63971243 STIP1 0.68 8.42 0.41 1.04e-15 Mean platelet volume; LIHC cis rs919433 0.680 rs699319 chr2:198281776 C/A cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.84e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs763121 0.853 rs1013338 chr22:38974154 C/A cg21395723 chr22:39101663 GTPBP1 0.43 7.42 0.37 9.23e-13 Menopause (age at onset); LIHC cis rs13064411 0.696 rs7622740 chr3:113206771 G/A cg18753928 chr3:113234510 CCDC52 -0.43 -6.18 -0.32 1.87e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs34779708 0.966 rs4934538 chr10:35472150 T/C cg04310649 chr10:35416472 CREM -0.42 -5.76 -0.3 1.91e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12824058 0.831 rs4759653 chr12:130812604 T/C cg26677194 chr12:130822605 PIWIL1 0.51 7.25 0.36 2.88e-12 Menopause (age at onset); LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg02993280 chr1:107599747 PRMT6 -0.63 -9.83 -0.47 2.96e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs769267 0.929 rs2905421 chr19:19457908 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.96 0.4 2.57e-14 Tonsillectomy; LIHC cis rs12477438 0.784 rs13407840 chr2:99569928 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.26 -0.41 3.27e-15 Chronic sinus infection; LIHC cis rs611744 0.967 rs631031 chr8:109190032 G/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs941408 1.000 rs1736181 chr19:2797703 C/T cg06609049 chr19:2785107 THOP1 0.61 9.64 0.46 1.33e-19 Total cholesterol levels; LIHC cis rs1559088 0.803 rs10405770 chr19:33616549 C/T cg17764715 chr19:33622953 WDR88 0.47 6.85 0.35 3.45e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg19635926 chr16:89946313 TCF25 0.54 7.38 0.37 1.25e-12 Skin colour saturation; LIHC cis rs892961 0.932 rs12452788 chr17:75406866 T/C cg05865280 chr17:75406074 SEPT9 0.63 12.79 0.57 6.95e-31 Airflow obstruction; LIHC cis rs12477438 0.501 rs12613624 chr2:99732741 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.82 -14.17 -0.61 3.38e-36 Chronic sinus infection; LIHC cis rs6752107 1.000 rs2241879 chr2:234183468 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.54 0.42 4.46e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs5758511 0.680 rs5758687 chr22:42656588 A/T cg20195005 chr22:42527684 CYP2D6 0.3 5.72 0.3 2.36e-8 Birth weight; LIHC cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg18230493 chr5:56204884 C5orf35 -0.46 -6.41 -0.33 4.94e-10 Initial pursuit acceleration; LIHC cis rs3741404 0.791 rs7102177 chr11:63909228 T/C cg04317338 chr11:64019027 PLCB3 0.49 6.69 0.34 9.11e-11 Platelet count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01320780 chr8:22298453 PPP3CC 0.45 6.51 0.33 2.67e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2710642 0.611 rs1534420 chr2:62884053 C/T cg17519650 chr2:63277830 OTX1 -0.46 -6.67 -0.34 1.01e-10 LDL cholesterol levels;LDL cholesterol; LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.09 0.75 7.41e-64 Height; LIHC cis rs7833790 0.632 rs6415653 chr8:82702536 A/G cg02079420 chr8:82753780 SNX16 0.34 6.06 0.31 3.63e-9 Diastolic blood pressure; LIHC cis rs7116495 1.000 rs7949480 chr11:71697588 T/C cg26138937 chr11:71823887 C11orf51 -0.81 -7.95 -0.39 2.8e-14 Severe influenza A (H1N1) infection; LIHC cis rs2153535 0.601 rs1928183 chr6:8530018 A/G cg23788917 chr6:8435910 SLC35B3 0.63 8.88 0.43 3.76e-17 Motion sickness; LIHC cis rs2549003 0.933 rs3846731 chr5:131814264 T/C cg21138405 chr5:131827807 IRF1 0.37 9.6 0.46 1.71e-19 Asthma (sex interaction); LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg15382696 chr6:118971807 C6orf204 0.62 6.27 0.32 1.06e-9 Diastolic blood pressure; LIHC cis rs807029 0.577 rs3740490 chr10:102756743 G/C cg27255678 chr10:102756921 LZTS2 0.52 7.29 0.37 2.22e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4853012 0.941 rs7571083 chr2:74342260 C/G cg05890377 chr2:74357713 NA 0.63 12.84 0.57 4.74e-31 Gestational age at birth (maternal effect); LIHC cis rs936229 0.871 rs2290574 chr15:75135447 T/C cg14664628 chr15:75095509 CSK -0.88 -14.83 -0.63 8.91e-39 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.49 0.56 9.45e-30 Prudent dietary pattern; LIHC cis rs10751667 0.666 rs7396059 chr11:970490 C/A cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs2839627 0.561 rs6586248 chr21:44257812 C/T cg03543861 chr21:44258195 NA 0.49 7.66 0.38 1.96e-13 Information processing speed; LIHC cis rs6429082 0.818 rs834198 chr1:235671987 A/G cg26050004 chr1:235667680 B3GALNT2 0.48 7.37 0.37 1.31e-12 Adiposity; LIHC trans rs1814175 0.712 rs9665784 chr11:50030617 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs8114671 0.562 rs6087651 chr20:33518353 C/T cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.01e-19 Height; LIHC cis rs8103278 1.000 rs11671524 chr19:46327166 G/A cg02376097 chr19:46275166 DMPK -0.46 -7.02 -0.35 1.19e-11 Coronary artery disease; LIHC cis rs12477438 0.798 rs10196680 chr2:99628617 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.52 -0.53 3.47e-26 Chronic sinus infection; LIHC cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg03060546 chr3:49711283 APEH 0.4 5.86 0.3 1.11e-8 Menarche (age at onset); LIHC trans rs4650994 0.905 rs12753251 chr1:178529898 G/A cg05059571 chr16:84539110 KIAA1609 -0.38 -6.37 -0.33 5.93e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs17826219 0.500 rs9891256 chr17:29072692 C/T cg14067834 chr17:29058358 SUZ12P 0.7 7.12 0.36 6.32e-12 Body mass index; LIHC cis rs10789491 1.000 rs618505 chr1:47144532 T/C cg15501359 chr1:47185051 KIAA0494 0.76 10.98 0.51 3.13e-24 Response to hepatitis C treatment; LIHC cis rs6089584 0.888 rs6089624 chr20:60619907 C/G cg13770153 chr20:60521292 NA -0.32 -6.51 -0.33 2.71e-10 Body mass index; LIHC cis rs9611565 0.649 rs139540 chr22:42178040 C/T cg06634786 chr22:41940651 POLR3H -0.54 -5.99 -0.31 5.17e-9 Vitiligo; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.86 0.8 1.15e-78 Prudent dietary pattern; LIHC cis rs1670533 1.000 rs2100411 chr4:1074412 T/C cg27284194 chr4:1044797 NA 0.6 8.94 0.44 2.57e-17 Recombination rate (females); LIHC cis rs8017423 0.967 rs11159957 chr14:90715972 A/G cg04374321 chr14:90722782 PSMC1 -0.73 -14.34 -0.61 7.85e-37 Mortality in heart failure; LIHC cis rs17270561 1.000 rs12211184 chr6:25823774 G/A cg16482183 chr6:26056742 HIST1H1C 0.54 6.35 0.32 6.85e-10 Iron status biomarkers; LIHC cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.75 -0.5 2e-23 Platelet count; LIHC cis rs10876993 0.680 rs2277322 chr12:58009202 T/C cg15848620 chr12:58087721 OS9 0.51 6.59 0.34 1.71e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs599083 0.573 rs3018713 chr11:68390986 A/G cg16797656 chr11:68205561 LRP5 0.49 8.53 0.42 4.65e-16 Bone mineral density (spine); LIHC cis rs7635838 0.684 rs2594965 chr3:11323799 G/C cg00170343 chr3:11313890 ATG7 0.6 10.26 0.49 9.98e-22 HDL cholesterol; LIHC cis rs8044995 0.568 rs112086775 chr16:68310917 A/C cg05110241 chr16:68378359 PRMT7 -0.71 -7.72 -0.39 1.28e-13 Schizophrenia; LIHC cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg02931644 chr1:25747376 RHCE -0.34 -7.42 -0.37 9.5e-13 Erythrocyte sedimentation rate; LIHC cis rs17253792 0.822 rs10133962 chr14:56066088 G/A cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs4660306 1.000 rs10157597 chr1:45990278 C/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.67 -0.34 1.02e-10 Homocysteine levels; LIHC cis rs11122272 0.735 rs2474623 chr1:231513993 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs2075371 0.966 rs1646676 chr7:133999267 G/A cg11752832 chr7:134001865 SLC35B4 0.52 7.63 0.38 2.29e-13 Mean platelet volume; LIHC cis rs9399135 1.000 rs11754265 chr6:135356216 C/G cg24558204 chr6:135376177 HBS1L 0.41 6.71 0.34 7.85e-11 Red blood cell count; LIHC cis rs77633900 0.772 rs283799 chr15:76752834 A/C cg21673338 chr15:77095150 SCAPER -0.52 -6.11 -0.31 2.78e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs6429082 0.509 rs6699315 chr1:235525253 C/T cg26050004 chr1:235667680 B3GALNT2 -0.45 -6.72 -0.34 7.46e-11 Adiposity; LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.07 -0.31 3.43e-9 Total body bone mineral density; LIHC cis rs4834770 1.000 rs4336213 chr4:120236469 G/T cg09307838 chr4:120376055 NA 0.41 6.14 0.32 2.27e-9 Blood protein levels; LIHC cis rs7635838 0.718 rs2594991 chr3:11362704 G/A cg00170343 chr3:11313890 ATG7 0.6 10.07 0.48 4.8e-21 HDL cholesterol; LIHC cis rs1538970 0.962 rs3219463 chr1:45806432 C/T cg24296786 chr1:45957014 TESK2 -0.56 -8.03 -0.4 1.64e-14 Platelet count; LIHC cis rs9640161 0.636 rs3735171 chr7:150033882 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.52 -8.52 -0.42 5.12e-16 Blood protein levels;Circulating chemerin levels; LIHC trans rs2096176 0.632 rs12572400 chr10:26312475 G/A cg01396774 chr2:218299024 DIRC3 -0.31 -6.08 -0.31 3.26e-9 Obesity-related traits; LIHC cis rs28595532 0.748 rs72670248 chr4:119335536 A/C cg21605333 chr4:119757512 SEC24D 1.06 8.55 0.42 4.25e-16 Cannabis dependence symptom count; LIHC cis rs2153535 0.580 rs6926759 chr6:8456176 G/A cg07606381 chr6:8435919 SLC35B3 0.8 11.9 0.54 1.44e-27 Motion sickness; LIHC cis rs6723226 0.772 rs2366894 chr2:32713706 A/T cg02381751 chr2:32503542 YIPF4 0.66 9.93 0.47 1.33e-20 Intelligence (multi-trait analysis); LIHC cis rs17102884 0.506 rs4899540 chr14:75403408 G/A cg08847533 chr14:75593920 NEK9 -0.62 -10.88 -0.51 7.12e-24 Neuroticism; LIHC trans rs6598955 0.671 rs3924325 chr1:26616320 T/C cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.21 -0.41 4.62e-15 Obesity-related traits; LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg01171360 chr6:293285 DUSP22 -0.45 -6.48 -0.33 3.19e-10 Menopause (age at onset); LIHC cis rs1023500 0.551 rs133371 chr22:42465574 G/A cg04733989 chr22:42467013 NAGA 0.66 9.69 0.46 9.09e-20 Schizophrenia; LIHC cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.34 0.55 3.52e-29 Alzheimer's disease; LIHC cis rs2153535 0.580 rs9505446 chr6:8448691 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1853665 0.580 rs6557200 chr6:150272532 C/T cg16301758 chr6:150275521 NA 0.41 6.19 0.32 1.75e-9 Radiation response; LIHC cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.44 0.33 4.09e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg20887711 chr4:1340912 KIAA1530 0.46 7.12 0.36 6.27e-12 Obesity-related traits; LIHC cis rs3768617 0.510 rs2027078 chr1:183073478 G/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.79 0.5 1.46e-23 Fuchs's corneal dystrophy; LIHC trans rs8073060 0.586 rs8064895 chr17:34001121 T/C cg19694781 chr19:47549865 TMEM160 -1.22 -12.48 -0.56 1.02e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9467773 1.000 rs2224380 chr6:26553943 G/A cg09904177 chr6:26538194 HMGN4 0.65 13.82 0.6 8.15e-35 Intelligence (multi-trait analysis); LIHC cis rs1046896 0.594 rs67813226 chr17:80851134 G/A cg22027946 chr17:80790580 TBCD;ZNF750 0.5 7.13 0.36 5.91e-12 Glycated hemoglobin levels; LIHC trans rs916888 0.821 rs199525 chr17:44847834 T/G cg07870213 chr5:140052090 DND1 1.02 10.14 0.48 2.72e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4294134 0.935 rs3110823 chr7:135357476 A/C cg20392616 chr7:135392013 SLC13A4 0.39 6.55 0.33 2.12e-10 Paget's disease; LIHC cis rs8062405 0.929 rs11864750 chr16:28875204 A/T cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4819052 1.000 rs9306123 chr21:46709922 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 10.79 0.5 1.48e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6582630 0.502 rs4379906 chr12:38295673 G/A cg26384229 chr12:38710491 ALG10B 0.58 8.14 0.4 7.59e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs477692 0.603 rs10829602 chr10:131326790 G/A cg19680672 chr10:131412579 MGMT -0.4 -6.04 -0.31 4e-9 Response to temozolomide; LIHC cis rs74181299 0.648 rs6730986 chr2:65353549 C/T cg05010058 chr2:65284262 CEP68 -0.41 -6.67 -0.34 1.06e-10 Pulse pressure; LIHC cis rs3749237 0.595 rs2878298 chr3:49406080 T/C cg07636037 chr3:49044803 WDR6 0.5 7.6 0.38 2.81e-13 Resting heart rate; LIHC cis rs1997103 1.000 rs11238364 chr7:55407632 G/T cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2204008 0.805 rs11179579 chr12:38213957 A/C cg13010199 chr12:38710504 ALG10B 0.48 5.71 0.3 2.42e-8 Bladder cancer; LIHC trans rs57221529 0.766 rs12519763 chr5:559145 C/T cg25482853 chr8:67687455 SGK3 0.67 6.67 0.34 1.03e-10 Lung disease severity in cystic fibrosis; LIHC cis rs2228479 0.850 rs62052714 chr16:89857180 T/C cg00800038 chr16:89945340 TCF25 -0.62 -8.84 -0.43 5.24e-17 Skin colour saturation; LIHC cis rs1707322 1.000 rs6671754 chr1:46433990 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.57 0.33 1.87e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7296418 0.699 rs11057219 chr12:123750073 T/C cg00376283 chr12:123451042 ABCB9 0.63 10.29 0.49 8.51e-22 Platelet count; LIHC cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs6705583 chr2:99602625 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -11.13 -0.52 8.93e-25 Chronic sinus infection; LIHC cis rs11055008 0.620 rs10845608 chr12:12836088 C/T cg09462578 chr12:12878428 APOLD1 0.46 7.23 0.36 3.27e-12 Pulse pressure; LIHC cis rs506338 0.517 rs17146216 chr11:64451281 C/G cg08800856 chr11:64428347 NRXN2 0.4 6.29 0.32 9.75e-10 Body mass index;Urate levels; LIHC cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg11890956 chr21:40555474 PSMG1 1.07 15.83 0.65 9.81e-43 Cognitive function; LIHC cis rs6964587 1.000 rs2299240 chr7:91654618 A/G cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs9368481 0.546 rs12664610 chr6:26885031 G/A cg18867708 chr6:26865862 GUSBL1 0.56 8.47 0.42 7.16e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs875971 0.862 rs1875057 chr7:65731855 A/G cg18252515 chr7:66147081 NA 0.47 6.89 0.35 2.67e-11 Aortic root size; LIHC cis rs5753037 0.838 rs140145 chr22:30178305 C/T cg01021169 chr22:30184971 ASCC2 -0.34 -6.35 -0.32 6.84e-10 Type 1 diabetes; LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg22903471 chr2:27725779 GCKR -0.51 -9.02 -0.44 1.4e-17 Total body bone mineral density; LIHC trans rs1005277 0.579 rs1780121 chr10:38529437 C/A cg23533926 chr12:111358616 MYL2 -0.33 -6.33 -0.32 7.73e-10 Extrinsic epigenetic age acceleration; LIHC cis rs11030122 0.702 rs4910868 chr11:3980224 A/C cg18678763 chr11:4115507 RRM1 -0.58 -8.56 -0.42 3.86e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs17685 0.623 rs7782808 chr7:75768645 C/T cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7927771 0.524 rs10458915 chr11:47864392 T/A cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC cis rs1368882 1.000 rs1368882 chr1:55107019 A/G cg01517571 chr1:55089959 ACOT11;FAM151A -0.39 -6.45 -0.33 3.93e-10 Non-substance related behavioral disinhibition; LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg11494091 chr17:61959527 GH2 0.45 8.13 0.4 7.75e-15 Prudent dietary pattern; LIHC cis rs7772486 0.686 rs9403741 chr6:146030548 G/A cg23711669 chr6:146136114 FBXO30 -0.64 -11.73 -0.54 6.08e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs10911232 0.507 rs10752891 chr1:183023283 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.68 0.5 3.74e-23 Hypertriglyceridemia; LIHC cis rs11626933 1.000 rs7149083 chr14:90754006 G/A cg14092571 chr14:90743983 NA -0.9 -14.83 -0.63 9.11e-39 Gut microbiota (bacterial taxa); LIHC cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg24642844 chr7:1081250 C7orf50 -0.91 -8.84 -0.43 5.07e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9457247 0.935 rs2149093 chr6:167373045 T/C cg07741184 chr6:167504864 NA -0.3 -6.88 -0.35 2.89e-11 Crohn's disease; LIHC cis rs3015497 0.967 rs3015483 chr14:51137474 C/G cg09863266 chr14:51125203 SAV1 -0.41 -6.62 -0.34 1.38e-10 Mean platelet volume; LIHC cis rs941408 1.000 rs941406 chr19:2803623 A/G cg06609049 chr19:2785107 THOP1 0.53 9.27 0.45 2.21e-18 Total cholesterol levels; LIHC trans rs2073499 0.872 rs58051625 chr3:50278717 G/C cg21659725 chr3:3221576 CRBN 0.64 6.43 0.33 4.35e-10 Schizophrenia; LIHC cis rs2463822 0.920 rs72923207 chr11:62117959 A/G cg06239285 chr11:62104954 ASRGL1 -0.96 -6.57 -0.33 1.86e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs4853012 0.838 rs60964317 chr2:74343423 A/T cg05890377 chr2:74357713 NA 0.63 12.69 0.57 1.62e-30 Gestational age at birth (maternal effect); LIHC cis rs13161895 1.000 rs17079968 chr5:179443423 C/T cg06664874 chr5:179499304 RNF130 0.58 7.22 0.36 3.48e-12 LDL cholesterol; LIHC cis rs6963495 0.818 rs73190133 chr7:105147821 G/C cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs748404 0.697 rs530683 chr15:43568999 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.44 -6.67 -0.34 1.03e-10 Lung cancer; LIHC cis rs72781680 0.583 rs6731333 chr2:24113354 C/T cg08917208 chr2:24149416 ATAD2B 0.67 6.8 0.35 4.56e-11 Lymphocyte counts; LIHC cis rs864643 1.000 rs689352 chr3:39550766 T/A cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs116095464 0.558 rs2288459 chr5:231143 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs55823223 0.564 rs9894009 chr17:73850414 C/T cg10935138 chr17:73851978 WBP2 0.68 9.02 0.44 1.34e-17 Psoriasis; LIHC cis rs7296418 0.599 rs2277343 chr12:123794450 A/T cg05973401 chr12:123451056 ABCB9 0.41 6.33 0.32 7.53e-10 Platelet count; LIHC cis rs1348850 0.526 rs9288003 chr2:178446572 T/G cg27490568 chr2:178487706 NA 1.03 11.96 0.54 9.22e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs2727020 0.553 rs3862350 chr11:49595912 A/C cg03929089 chr4:120376271 NA -0.89 -16.92 -0.68 4.31e-47 Coronary artery disease; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg02290350 chr8:58132656 NA 0.5 10.96 0.51 3.66e-24 Developmental language disorder (linguistic errors); LIHC cis rs12497850 0.931 rs9835307 chr3:48857805 T/C cg06212747 chr3:49208901 KLHDC8B 0.55 7.07 0.36 8.98e-12 Parkinson's disease; LIHC cis rs273218 0.573 rs16882051 chr5:53342979 T/C ch.5.1024479R chr5:53302184 ARL15 -0.9 -15.84 -0.65 9.08e-43 Migraine; LIHC cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg09323728 chr8:95962352 TP53INP1 -0.28 -6.06 -0.31 3.54e-9 Type 2 diabetes; LIHC cis rs9914988 0.943 rs9890155 chr17:27125467 A/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg08219700 chr8:58056026 NA 0.55 8.96 0.44 2.2e-17 Developmental language disorder (linguistic errors); LIHC cis rs988712 0.705 rs4244531 chr11:27657250 A/G cg18117895 chr11:27722066 BDNF 0.45 6.11 0.31 2.71e-9 Obesity; LIHC cis rs10056811 0.538 rs2035191 chr5:74413713 T/C cg00601450 chr5:74908170 NA 0.45 5.86 0.3 1.07e-8 Coronary artery disease; LIHC cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg00612595 chr21:47717864 NA -0.35 -5.86 -0.3 1.12e-8 Testicular germ cell tumor; LIHC cis rs4925386 1.000 rs1889201 chr20:60923075 C/T cg06026331 chr20:60912101 LAMA5 -0.51 -8.7 -0.43 1.38e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg10411590 chr13:21900810 NA 0.46 7.63 0.38 2.3e-13 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2070488 1.000 rs1002675 chr3:38445226 C/T cg24069376 chr3:38537580 EXOG 0.41 7.36 0.37 1.41e-12 Electrocardiographic conduction measures; LIHC trans rs9531686 1.000 rs9546995 chr13:85547170 A/G cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.3 0.32 9.31e-10 Anorexia nervosa; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18574395 chr18:9102960 NDUFV2 0.47 6.42 0.33 4.5e-10 Pancreatic cancer; LIHC cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg11764359 chr7:65958608 NA -0.57 -5.92 -0.31 7.72e-9 Diabetic kidney disease; LIHC cis rs7296418 0.738 rs10846489 chr12:123743927 A/G cg00376283 chr12:123451042 ABCB9 -0.64 -10.4 -0.49 3.34e-22 Platelet count; LIHC cis rs5769765 0.908 rs7410601 chr22:50317187 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -8.87 -0.43 4.15e-17 Schizophrenia; LIHC cis rs7618501 1.000 rs7372725 chr3:49790544 C/A cg24110177 chr3:50126178 RBM5 0.42 6.49 0.33 3.1e-10 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.620 rs7373821 chr3:47080127 A/C cg16586182 chr3:47516702 SCAP -0.47 -8.57 -0.42 3.7e-16 Colorectal cancer; LIHC cis rs6714710 0.580 rs6711101 chr2:98379813 G/A cg26665480 chr2:98280029 ACTR1B 0.45 6.41 0.33 4.73e-10 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs17401966 0.838 rs10492971 chr1:10342975 G/A cg15208524 chr1:10270712 KIF1B 0.38 5.85 0.3 1.18e-8 Hepatocellular carcinoma; LIHC cis rs7238033 0.624 rs7234310 chr18:43306793 G/A cg20610511 chr18:43302872 SLC14A1 0.4 6.65 0.34 1.13e-10 Bladder cancer; LIHC cis rs2230307 0.572 rs514090 chr1:100563186 C/G cg24955406 chr1:100503596 HIAT1 0.61 6.06 0.31 3.51e-9 Carotid intima media thickness; LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg26338869 chr17:61819248 STRADA 0.52 6.95 0.35 1.83e-11 Height; LIHC cis rs7945718 0.905 rs4454698 chr11:12720560 A/G cg25843174 chr11:12811716 TEAD1 -0.34 -7.58 -0.38 3.23e-13 Educational attainment (years of education); LIHC cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg05555928 chr11:63887634 MACROD1 0.55 7.42 0.37 9.28e-13 Mean platelet volume; LIHC cis rs10489202 0.954 rs12403023 chr1:168086999 A/G cg17859187 chr1:168147929 TIPRL 0.52 6.8 0.34 4.77e-11 Schizophrenia; LIHC cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg08219700 chr8:58056026 NA 0.45 5.76 0.3 1.85e-8 Developmental language disorder (linguistic errors); LIHC cis rs10504073 0.647 rs4348510 chr8:50016027 C/A cg00325661 chr8:49890786 NA 0.31 7.13 0.36 6.13e-12 Blood metabolite ratios; LIHC cis rs208520 0.661 rs207079 chr6:66770462 C/T cg07460842 chr6:66804631 NA -0.81 -9.45 -0.46 5.43e-19 Exhaled nitric oxide output; LIHC cis rs1801251 1.000 rs2674839 chr2:233669040 G/C cg08000102 chr2:233561755 GIGYF2 0.75 11.1 0.51 1.19e-24 Coronary artery disease; LIHC cis rs6120849 0.707 rs752075 chr20:33591591 C/A cg24642439 chr20:33292090 TP53INP2 0.66 7.22 0.36 3.49e-12 Protein C levels; LIHC cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.41 -5.81 -0.3 1.41e-8 Colorectal cancer; LIHC cis rs782590 0.967 rs782592 chr2:55843875 T/A cg03859395 chr2:55845619 SMEK2 0.7 11.22 0.52 4.45e-25 Metabolic syndrome; LIHC cis rs6977660 1.000 rs5017191 chr7:19820158 C/A cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs3096299 0.967 rs28689480 chr16:89460093 T/C cg02187348 chr16:89574699 SPG7 0.51 7.48 0.37 6.39e-13 Multiple myeloma (IgH translocation); LIHC cis rs4925386 0.681 rs2427296 chr20:60927475 G/A cg06026331 chr20:60912101 LAMA5 0.63 9.36 0.45 1.08e-18 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs1997103 0.954 rs4947505 chr7:55409448 T/C cg17469321 chr7:55412551 NA 0.48 7.1 0.36 7.32e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs875971 0.862 rs1612452 chr7:65573896 T/A cg18252515 chr7:66147081 NA 0.43 5.98 0.31 5.63e-9 Aortic root size; LIHC cis rs6988636 1.000 rs60362869 chr8:124189971 A/G cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs7116495 0.618 rs669835 chr11:71566075 T/C cg26138937 chr11:71823887 C11orf51 0.65 6.31 0.32 8.62e-10 Severe influenza A (H1N1) infection; LIHC cis rs910316 0.687 rs175059 chr14:75490667 T/C cg08847533 chr14:75593920 NEK9 -0.89 -18.03 -0.7 1.44e-51 Height; LIHC trans rs61931739 0.534 rs7313137 chr12:34010231 T/G cg26384229 chr12:38710491 ALG10B 0.51 7.14 0.36 5.65e-12 Morning vs. evening chronotype; LIHC cis rs3796619 1.000 rs13146371 chr4:1082887 C/T cg27284194 chr4:1044797 NA 0.62 10.12 0.48 3.02e-21 Recombination rate (males); LIHC cis rs2204008 0.837 rs7974888 chr12:37945215 A/G cg26384229 chr12:38710491 ALG10B 0.81 10.49 0.49 1.62e-22 Bladder cancer; LIHC cis rs700651 0.789 rs116165148 chr2:198888347 T/G cg10820045 chr2:198174542 NA 0.43 6.51 0.33 2.64e-10 Intracranial aneurysm; LIHC cis rs4555082 0.834 rs2735817 chr14:105717796 A/G cg10792982 chr14:105748885 BRF1 -0.52 -6.84 -0.35 3.71e-11 Mean platelet volume;Platelet distribution width; LIHC cis rs6665290 0.901 rs68087483 chr1:227202668 T/C cg10327440 chr1:227177885 CDC42BPA -1.15 -28.19 -0.84 3.3e-91 Myeloid white cell count; LIHC cis rs9916302 0.706 rs801427 chr17:37436711 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -11.93 -0.54 1.17e-27 Glomerular filtration rate (creatinine); LIHC cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg18357526 chr6:26021779 HIST1H4A -0.54 -7.12 -0.36 6.23e-12 Blood metabolite levels; LIHC cis rs896854 0.738 rs481887 chr8:95967838 A/G cg09323728 chr8:95962352 TP53INP1 0.3 5.83 0.3 1.27e-8 Type 2 diabetes; LIHC cis rs9303401 0.527 rs7224468 chr17:56749943 C/T cg25039879 chr17:56429692 SUPT4H1 0.76 8.2 0.41 4.97e-15 Cognitive test performance; LIHC cis rs858239 1.000 rs199351 chr7:23300049 A/C cg00469287 chr7:23338798 C7orf30 0.42 5.86 0.3 1.08e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs6500602 0.826 rs11076831 chr16:4460133 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.44 -6.32 -0.32 8.35e-10 Schizophrenia; LIHC cis rs3770081 0.590 rs12623761 chr2:86505712 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.68 -6.91 -0.35 2.45e-11 Facial emotion recognition (sad faces); LIHC cis rs4555082 0.874 rs2142190 chr14:105719306 G/A cg10792982 chr14:105748885 BRF1 0.5 6.56 0.33 2.05e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.72 0.39 1.26e-13 Prudent dietary pattern; LIHC cis rs10131894 0.611 rs174994 chr14:75434102 A/G cg11812906 chr14:75593930 NEK9 -0.65 -11.32 -0.52 1.9e-25 Coronary artery disease; LIHC cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg03806693 chr22:41940476 POLR3H 0.97 10.4 0.49 3.29e-22 Vitiligo; LIHC cis rs801193 0.660 rs1962050 chr7:66240008 C/T cg18876405 chr7:65276391 NA -0.32 -5.91 -0.3 8.49e-9 Aortic root size; LIHC cis rs17376456 0.825 rs10053405 chr5:93275403 A/G cg25358565 chr5:93447407 FAM172A -0.94 -8.78 -0.43 8.18e-17 Diabetic retinopathy; LIHC cis rs7772486 0.521 rs9485017 chr6:146023326 C/T cg23711669 chr6:146136114 FBXO30 0.6 9.54 0.46 2.71e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs8072100 0.512 rs9674670 chr17:45386157 G/A cg25173405 chr17:45401733 C17orf57 -0.44 -5.9 -0.3 8.64e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs28374715 0.662 rs13329579 chr15:41467435 C/T cg18705301 chr15:41695430 NDUFAF1 -0.82 -9.15 -0.44 5.23e-18 Ulcerative colitis; LIHC cis rs1008375 0.932 rs11938710 chr4:17670664 G/C cg16339924 chr4:17578868 LAP3 -0.46 -6.1 -0.31 2.93e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs76419734 0.510 rs28450989 chr4:106630007 G/C cg24545054 chr4:106630052 GSTCD;INTS12 0.77 8.77 0.43 8.36e-17 Post bronchodilator FEV1; LIHC cis rs7129556 0.539 rs1945747 chr11:77277387 A/T cg03570279 chr11:77446074 RSF1 -0.35 -6.51 -0.33 2.63e-10 Weight loss (gastric bypass surgery); LIHC cis rs116095464 0.558 rs6555052 chr5:224268 G/A cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs9640161 0.702 rs1962004 chr7:150020381 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.52 -8.58 -0.42 3.48e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs703842 0.964 rs10431552 chr12:58178148 G/A cg18357645 chr12:58087776 OS9 -0.44 -6.9 -0.35 2.48e-11 Multiple sclerosis; LIHC cis rs5997397 0.967 rs5762777 chr22:29150044 T/C cg15103426 chr22:29168792 CCDC117 0.55 8.71 0.43 1.35e-16 Red cell distribution width; LIHC cis rs3796352 1.000 rs34313969 chr3:52995166 A/G cg07884673 chr3:53033167 SFMBT1 0.9 6.59 0.34 1.65e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg21448741 chr8:58168803 NA -0.35 -6.45 -0.33 3.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs66887589 0.837 rs6534135 chr4:120406302 A/G cg25214090 chr10:38739885 LOC399744 0.39 6.51 0.33 2.75e-10 Diastolic blood pressure; LIHC cis rs2839186 1.000 rs2839186 chr21:47690068 C/T cg09417038 chr21:47716443 C21orf57 -0.49 -7.21 -0.36 3.56e-12 Testicular germ cell tumor; LIHC cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs7131987 0.650 rs7954871 chr12:29459732 G/A cg00204748 chr12:29376779 FAR2 0.38 6.99 0.35 1.44e-11 QT interval; LIHC trans rs2486152 0.786 rs61867311 chr10:108544720 T/C cg09955886 chr10:7603804 ITIH5 0.54 6.03 0.31 4.15e-9 Metabolite levels (Pyroglutamine); LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg26010095 chr1:52522216 TXNDC12;BTF3L4 0.45 6.12 0.31 2.63e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg06640241 chr16:89574553 SPG7 0.82 15.21 0.64 2.95e-40 Multiple myeloma (IgH translocation); LIHC cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg05025164 chr4:1340916 KIAA1530 0.63 9.43 0.45 6.46e-19 Longevity; LIHC cis rs6754311 0.517 rs1865452 chr2:136539330 C/T cg07169764 chr2:136633963 MCM6 1.04 14.34 0.61 7.85e-37 Mosquito bite size; LIHC cis rs735860 0.763 rs1346603 chr6:53149262 C/T cg10236188 chr6:53219634 NA 0.4 7.26 0.37 2.68e-12 Glaucoma; LIHC cis rs2404602 0.669 rs12441484 chr15:77109875 G/A cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.9e-38 Blood metabolite levels; LIHC cis rs7762018 0.607 rs75964125 chr6:170054290 T/A cg19338460 chr6:170058176 WDR27 -0.84 -9.25 -0.45 2.56e-18 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs1348850 0.526 rs4243389 chr2:178379783 G/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.67 5.76 0.3 1.89e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs2270927 0.510 rs6453214 chr5:75584423 A/G cg13563193 chr19:33072644 PDCD5 0.97 9.13 0.44 5.94e-18 Mean corpuscular volume; LIHC cis rs427394 0.659 rs187295 chr5:6734326 C/T cg10857441 chr5:6722123 POLS -0.39 -6.55 -0.33 2.18e-10 Menopause (age at onset); LIHC cis rs2120019 0.505 rs77456790 chr15:75330095 G/T cg16226627 chr15:75307476 SCAMP5 0.54 9.01 0.44 1.47e-17 Blood trace element (Zn levels); LIHC cis rs4819052 0.851 rs13047104 chr21:46673562 T/G cg22633049 chr21:46681294 NA -0.37 -6.29 -0.32 9.79e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25733915 chr17:40829168 PLEKHH3 0.48 6.94 0.35 1.92e-11 Pancreatic cancer; LIHC cis rs6708331 0.517 rs12617812 chr2:70359471 A/G cg01613454 chr2:70366299 NA 0.38 6.11 0.31 2.75e-9 Obesity-related traits; LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.55 -7.76 -0.39 9.71e-14 Lymphocyte counts; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17412405 chr5:114880687 FEM1C 0.47 6.41 0.33 4.95e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs738322 0.574 rs738323 chr22:38569527 C/T cg25457927 chr22:38595422 NA -0.31 -7.08 -0.36 8.44e-12 Cutaneous nevi; LIHC cis rs9457247 0.508 rs6941355 chr6:167506238 A/G cg07741184 chr6:167504864 NA 0.26 6.29 0.32 9.74e-10 Crohn's disease; LIHC cis rs2952156 0.883 rs8077172 chr17:37834977 G/T cg00129232 chr17:37814104 STARD3 -0.53 -10.19 -0.48 1.76e-21 Asthma; LIHC cis rs250677 1.000 rs250677 chr5:148433549 T/C cg18129178 chr5:148520854 ABLIM3 -0.45 -7.23 -0.36 3.23e-12 Breast cancer; LIHC trans rs71007656 1 rs71007656 chr10:37970845 CGGCTG/C cg23533926 chr12:111358616 MYL2 -0.32 -6.35 -0.32 6.79e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9783347 1.000 rs2061164 chr11:18329006 T/C cg15585147 chr11:18324498 HPS5 0.44 6.81 0.35 4.35e-11 Pancreatic cancer; LIHC trans rs7615952 0.932 rs3811679 chr3:125648283 A/G cg07211511 chr3:129823064 LOC729375 -0.84 -10.67 -0.5 3.77e-23 Blood pressure (smoking interaction); LIHC trans rs1464321 0.901 rs7302493 chr12:103652558 T/G cg15403093 chr12:133312361 ANKLE2 0.38 6.05 0.31 3.78e-9 Body mass index; LIHC cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 9.3 0.45 1.69e-18 Platelet count; LIHC cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg21664854 chr7:1097933 C7orf50;GPR146 0.76 5.84 0.3 1.24e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6840360 1.000 rs4571 chr4:152592191 T/C cg22705602 chr4:152727874 NA -0.3 -6.32 -0.32 8.21e-10 Intelligence (multi-trait analysis); LIHC cis rs74417235 0.684 rs13179754 chr5:154059845 C/T cg08893839 chr5:154027129 NA 0.49 6.97 0.35 1.59e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs559928 0.606 rs12419038 chr11:63912736 A/G cg05555928 chr11:63887634 MACROD1 -0.5 -5.94 -0.31 6.94e-9 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7116495 1.000 rs4945426 chr11:71748146 A/C cg26138937 chr11:71823887 C11orf51 0.78 7.59 0.38 3.12e-13 Severe influenza A (H1N1) infection; LIHC cis rs611744 0.967 rs702801 chr8:109211802 T/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs9896052 0.614 rs11077791 chr17:73474629 T/G cg25649188 chr17:73499917 CASKIN2 0.43 6.52 0.33 2.55e-10 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.8e-30 Menopause (age at onset); LIHC cis rs17345786 0.628 rs11718446 chr3:101552553 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 7.31 0.37 1.85e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs11098499 0.954 rs2389802 chr4:120325732 C/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg18252515 chr7:66147081 NA -1.24 -15.89 -0.65 5.57e-43 Diabetic kidney disease; LIHC cis rs17253792 0.822 rs77555779 chr14:56078430 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.6 -0.34 1.56e-10 Putamen volume; LIHC cis rs10504229 0.636 rs72649123 chr8:58045789 A/T cg02290350 chr8:58132656 NA 0.32 7.17 0.36 4.73e-12 Developmental language disorder (linguistic errors); LIHC cis rs9810089 0.814 rs2688600 chr3:136252596 C/A cg21827317 chr3:136751795 NA 0.45 6.03 0.31 4.34e-9 Gestational age at birth (child effect); LIHC cis rs2637266 0.935 rs2579775 chr10:78401677 G/A cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs3099143 1.000 rs7172639 chr15:77165288 G/A cg21673338 chr15:77095150 SCAPER 0.49 7.71 0.38 1.42e-13 Recalcitrant atopic dermatitis; LIHC cis rs2806561 0.765 rs623988 chr1:23519477 C/T cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.45e-11 Height; LIHC cis rs2439831 0.850 rs28696802 chr15:44140395 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.7 0.34 8.58e-11 Lung cancer in ever smokers; LIHC cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg07636037 chr3:49044803 WDR6 0.76 12.64 0.56 2.48e-30 Menarche (age at onset); LIHC cis rs7249142 0.562 rs1050544 chr19:19287901 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.44 -7.39 -0.37 1.16e-12 IgG glycosylation; LIHC cis rs8114671 0.562 rs959829 chr20:33346047 T/C cg08999081 chr20:33150536 PIGU -0.34 -5.75 -0.3 1.98e-8 Height; LIHC cis rs4665809 0.590 rs11126339 chr2:26253223 T/C cg04944784 chr2:26401820 FAM59B -0.56 -7.18 -0.36 4.5e-12 Gut microbiome composition (summer); LIHC cis rs8180040 1.000 rs295449 chr3:47375955 G/A cg27129171 chr3:47204927 SETD2 0.63 10.84 0.51 9.98e-24 Colorectal cancer; LIHC cis rs1008375 0.966 rs2315553 chr4:17627332 T/C cg16339924 chr4:17578868 LAP3 0.44 6.2 0.32 1.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3008870 0.959 rs2985816 chr1:67387750 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.45 0.66 3.47e-45 Lymphocyte percentage of white cells; LIHC trans rs17685 0.712 rs7794454 chr7:75776010 A/G cg19862616 chr7:65841803 NCRNA00174 -0.79 -15.13 -0.63 5.84e-40 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6964587 1.000 rs7797834 chr7:91743150 C/T cg17063962 chr7:91808500 NA -1.02 -19.78 -0.73 1.29e-58 Breast cancer; LIHC cis rs3749237 0.595 rs1464568 chr3:49458266 G/A cg03060546 chr3:49711283 APEH 0.6 10.0 0.48 8.02e-21 Resting heart rate; LIHC cis rs2404602 0.647 rs118129828 chr15:77015200 T/C cg03037974 chr15:76606532 NA -0.61 -10.33 -0.49 5.76e-22 Blood metabolite levels; LIHC cis rs25645 0.744 rs66826786 chr17:38206092 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.76 14.24 0.61 1.84e-36 Myeloid white cell count; LIHC cis rs9916302 0.851 rs11078904 chr17:37650569 G/A cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC cis rs15676 0.783 rs7044955 chr9:131567152 C/T cg00228799 chr9:131580591 ENDOG -0.47 -6.7 -0.34 8.42e-11 Blood metabolite levels; LIHC cis rs11227306 0.934 rs11227315 chr11:65590389 C/A cg00576331 chr11:65640516 EFEMP2 -0.41 -5.9 -0.3 8.79e-9 DNA methylation (variation); LIHC cis rs4660306 0.961 rs1337902 chr1:45952066 G/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.65 -7.77 -0.39 9.35e-14 Homocysteine levels; LIHC trans rs931812 1.000 rs4734495 chr8:101917817 C/A cg20993868 chr7:22813445 NA 0.3 6.63 0.34 1.32e-10 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs1008375 1.000 rs7659718 chr4:17638020 A/C cg02297831 chr4:17616191 MED28 0.51 7.95 0.39 2.76e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12142240 0.698 rs66483119 chr1:46838389 T/C cg00530320 chr1:46809349 NSUN4 0.54 5.77 0.3 1.76e-8 Menopause (age at onset); LIHC cis rs4555082 0.874 rs3000075 chr14:105713219 C/T cg13114125 chr14:105738426 BRF1 0.69 9.38 0.45 9.18e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs9715521 0.588 rs11731207 chr4:59852246 G/A cg11281224 chr4:60001000 NA -0.33 -6.23 -0.32 1.35e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs912057 0.671 rs1294435 chr6:6745455 G/A cg06612196 chr6:6737390 NA 0.51 9.4 0.45 8.37e-19 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs6456156 0.565 rs7750209 chr6:167482895 T/G cg12798992 chr6:167411361 FGFR1OP 0.43 6.54 0.33 2.28e-10 Primary biliary cholangitis; LIHC cis rs921968 0.541 rs58650092 chr2:219304851 C/A cg18887096 chr2:219472410 PLCD4 -0.39 -5.96 -0.31 6.25e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg27297192 chr10:134578999 INPP5A 0.55 8.03 0.4 1.63e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1018836 0.923 rs7833025 chr8:91568470 G/C cg16814680 chr8:91681699 NA -0.61 -9.75 -0.47 5.44e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9790314 0.586 rs11710086 chr3:161125858 A/T cg17135325 chr3:160939158 NMD3 0.47 7.11 0.36 6.79e-12 Morning vs. evening chronotype; LIHC cis rs7249142 0.549 rs12975253 chr19:19279745 A/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.88 -0.35 2.87e-11 IgG glycosylation; LIHC cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC cis rs13256369 1.000 rs10110591 chr8:8576608 G/T cg17143192 chr8:8559678 CLDN23 -0.79 -14.36 -0.61 6.53e-37 Obesity-related traits; LIHC cis rs1552244 0.882 rs13062917 chr3:10017032 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08793459 chr17:57784647 PTRH2;TMEM49 0.43 6.33 0.32 7.48e-10 Cognitive function; LIHC cis rs8083850 0.731 rs8084830 chr18:50835809 T/C cg24270629 chr18:50823537 DCC -0.53 -8.12 -0.4 8.29e-15 Intelligence (multi-trait analysis); LIHC cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg18404041 chr3:52824283 ITIH1 -0.51 -8.46 -0.42 7.67e-16 Cognitive function; LIHC cis rs637571 0.522 rs503524 chr11:65751764 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.4 6.02 0.31 4.48e-9 Eosinophil percentage of white cells; LIHC cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg17372223 chr3:52568218 NT5DC2 0.36 5.94 0.31 6.91e-9 Electroencephalogram traits; LIHC cis rs9868809 0.505 rs13063223 chr3:48750340 G/A cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.6e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs6582630 0.554 rs7299735 chr12:38450890 A/C cg26384229 chr12:38710491 ALG10B -0.45 -5.85 -0.3 1.16e-8 Drug-induced liver injury (flucloxacillin); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01334186 chr1:151372572 PSMB4 0.44 7.71 0.38 1.36e-13 Cognitive function; LIHC cis rs34779708 0.733 rs12240638 chr10:35542610 G/T cg03585969 chr10:35415529 CREM 0.76 11.02 0.51 2.18e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg05590025 chr7:65112418 INTS4L2 -0.58 -6.51 -0.33 2.61e-10 Diabetic kidney disease; LIHC cis rs709400 1.000 rs2403205 chr14:104143385 C/T cg26031613 chr14:104095156 KLC1 1.05 14.04 0.6 1.14e-35 Body mass index; LIHC cis rs796364 0.951 rs281769 chr2:200809709 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.16 0.44 4.71e-18 Schizophrenia; LIHC cis rs9640161 0.617 rs73170169 chr7:150008036 G/A cg27494647 chr7:150038898 RARRES2 0.34 6.33 0.32 7.59e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs11098499 0.955 rs13129661 chr4:120152909 C/G cg09307838 chr4:120376055 NA 0.75 10.87 0.51 7.89e-24 Corneal astigmatism; LIHC cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg26531700 chr6:26746687 NA 0.34 5.76 0.3 1.86e-8 Intelligence (multi-trait analysis); LIHC cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 8.51 0.42 5.74e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs7264396 0.563 rs2425122 chr20:34328848 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.68 -0.43 1.59e-16 Total cholesterol levels; LIHC cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.06e-11 Alzheimer's disease; LIHC cis rs6788895 1.000 rs41372346 chr3:150489116 C/G cg07663535 chr3:150480033 SIAH2 0.57 7.17 0.36 4.53e-12 Breast cancer; LIHC cis rs35883536 0.647 rs10875312 chr1:101042320 G/C cg14515779 chr1:101123966 NA 0.46 6.58 0.34 1.73e-10 Monocyte count; LIHC cis rs10878977 0.565 rs56810029 chr12:69809869 C/T cg17330252 chr12:69809627 NA 0.38 5.97 0.31 6.01e-9 Colorectal cancer; LIHC cis rs7937682 0.793 rs4581484 chr11:111415822 G/A cg09085632 chr11:111637200 PPP2R1B 0.73 8.4 0.41 1.23e-15 Primary sclerosing cholangitis; LIHC cis rs7216064 1.000 rs12602912 chr17:65870073 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs1062177 1.000 rs1062177 chr5:151184701 C/T cg00977110 chr5:151150581 G3BP1 0.55 7.05 0.36 1.01e-11 Preschool internalizing problems; LIHC cis rs710216 0.843 rs10890232 chr1:43416514 C/T cg03128534 chr1:43423976 SLC2A1 0.51 7.16 0.36 5.03e-12 Red cell distribution width; LIHC cis rs6952808 0.609 rs12699453 chr7:1953056 C/T cg02951883 chr7:2050386 MAD1L1 -0.53 -8.08 -0.4 1.09e-14 Bipolar disorder and schizophrenia; LIHC cis rs4934494 0.727 rs12783845 chr10:91482629 A/T cg19698084 chr10:91461284 KIF20B -0.47 -6.35 -0.32 6.84e-10 Red blood cell count; LIHC cis rs5753618 0.583 rs738657 chr22:31841749 T/A cg02404636 chr22:31891804 SFI1 0.35 6.14 0.32 2.28e-9 Colorectal cancer; LIHC cis rs950169 0.526 rs698620 chr15:85177208 G/A cg12501888 chr15:85177176 SCAND2 -0.5 -7.73 -0.39 1.21e-13 Schizophrenia; LIHC cis rs546131 0.928 rs553789 chr11:34827579 G/A cg11058730 chr11:34937778 PDHX;APIP 0.63 9.52 0.46 3.19e-19 Lung disease severity in cystic fibrosis; LIHC cis rs734999 0.545 rs10797436 chr1:2538349 G/A cg18854424 chr1:2615690 NA 0.32 6.92 0.35 2.22e-11 Ulcerative colitis; LIHC cis rs8060686 0.545 rs12598630 chr16:68258852 T/G cg05110241 chr16:68378359 PRMT7 -0.61 -6.77 -0.34 5.71e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs273218 1.000 rs168861 chr5:53377310 T/C ch.5.1024479R chr5:53302184 ARL15 0.65 10.32 0.49 6.48e-22 Migraine; LIHC cis rs12477438 0.765 rs12470471 chr2:99689141 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.51 7.38 0.37 1.21e-12 Chronic sinus infection; LIHC cis rs2404602 0.536 rs7163946 chr15:76766049 C/G cg23625390 chr15:77176239 SCAPER 0.36 5.79 0.3 1.59e-8 Blood metabolite levels; LIHC cis rs919433 0.963 rs10153881 chr2:198171098 T/C cg03934865 chr2:198174659 NA -0.57 -9.01 -0.44 1.5e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1008375 0.966 rs10939736 chr4:17581617 T/A cg02297831 chr4:17616191 MED28 0.48 7.23 0.36 3.19e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9291683 0.679 rs13137795 chr4:10051506 G/A cg11266682 chr4:10021025 SLC2A9 0.35 7.45 0.37 7.8e-13 Bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06612452 chr1:20960677 PINK1 0.5 7.21 0.36 3.58e-12 Pancreatic cancer; LIHC cis rs12744310 0.887 rs12724690 chr1:41800257 T/C cg03387723 chr1:41708464 SCMH1 -0.32 -5.82 -0.3 1.37e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2073300 1.000 rs74273799 chr20:23444492 T/C cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1046896 1.000 rs1046875 chr17:80685426 A/G cg02398342 chr17:80708632 TBCD;FN3K -0.45 -6.91 -0.35 2.44e-11 Glycated hemoglobin levels; LIHC cis rs6976053 0.541 rs314359 chr7:100411278 T/C cg08302003 chr7:100435192 NA -0.39 -6.32 -0.32 8.02e-10 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC cis rs7107174 1.000 rs10793300 chr11:78019582 T/A cg02023728 chr11:77925099 USP35 0.52 9.96 0.47 1.13e-20 Testicular germ cell tumor; LIHC cis rs7264396 0.836 rs6058282 chr20:34212590 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -9.53 -0.46 2.99e-19 Total cholesterol levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11865413 chr10:72969054 NA 0.44 6.25 0.32 1.25e-9 Pancreatic cancer; LIHC cis rs4906332 1.000 rs35224956 chr14:103900481 A/G cg19000871 chr14:103996768 TRMT61A -0.45 -7.81 -0.39 7.15e-14 Coronary artery disease; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg18279126 chr7:2041391 MAD1L1 0.38 6.42 0.33 4.59e-10 Bipolar disorder and schizophrenia; LIHC cis rs4242434 0.854 rs3064 chr8:22451688 C/G cg14690197 chr8:22456421 C8orf58 -0.4 -6.42 -0.33 4.46e-10 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs4908760 0.864 rs12136766 chr1:8663821 C/T cg20416874 chr1:8611966 RERE -0.61 -12.45 -0.56 1.39e-29 Vitiligo; LIHC cis rs1986734 0.576 rs2068062 chr4:77417214 A/C cg24201034 chr4:77507246 SHROOM3 -0.37 -5.86 -0.3 1.07e-8 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs7520050 0.966 rs7556436 chr1:46363880 C/T cg03146154 chr1:46216737 IPP 0.37 6.1 0.31 2.87e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6582630 0.519 rs8189549 chr12:38245752 A/G cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.56e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs7124681 0.584 rs4752792 chr11:47815702 G/A cg20307385 chr11:47447363 PSMC3 -0.66 -9.97 -0.47 1.01e-20 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs35110281 0.744 rs8131027 chr21:45104908 G/C cg21573476 chr21:45109991 RRP1B -0.51 -9.66 -0.46 1.15e-19 Mean corpuscular volume; LIHC cis rs77861329 1.000 rs9868101 chr3:52138377 T/C cg08692210 chr3:52188851 WDR51A 0.84 8.05 0.4 1.41e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs796364 0.760 rs74993507 chr2:201068684 C/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.44 -0.42 9.27e-16 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25804072 chr2:10829725 NOL10 0.5 7.04 0.36 1.09e-11 Pancreatic cancer; LIHC cis rs2637266 1.000 rs2395390 chr10:78357734 C/G cg18941641 chr10:78392320 NA 0.28 5.88 0.3 9.74e-9 Pulmonary function; LIHC cis rs6570726 0.791 rs383841 chr6:145888329 G/T cg23711669 chr6:146136114 FBXO30 -0.75 -13.55 -0.59 9.23e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs9311474 0.575 rs4434138 chr3:52556890 A/G cg18404041 chr3:52824283 ITIH1 -0.44 -7.06 -0.36 9.53e-12 Electroencephalogram traits; LIHC cis rs2370759 1.000 rs11597888 chr10:32635834 G/A cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs3106136 0.527 rs2664894 chr4:95153831 T/C cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.02 -0.44 1.33e-17 Capecitabine sensitivity; LIHC cis rs79149102 0.579 rs12591994 chr15:75320306 A/G cg16226627 chr15:75307476 SCAMP5 0.55 9.55 0.46 2.53e-19 Lung cancer; LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg06873352 chr17:61820015 STRADA 0.59 8.92 0.43 2.93e-17 Height; LIHC cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.33 0.37 1.67e-12 Electroencephalogram traits; LIHC cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg18402987 chr7:1209562 NA 0.41 5.77 0.3 1.79e-8 Longevity;Endometriosis; LIHC cis rs6582630 0.555 rs1969362 chr12:38514843 C/T cg13010199 chr12:38710504 ALG10B 0.44 6.13 0.31 2.47e-9 Drug-induced liver injury (flucloxacillin); LIHC trans rs6934970 0.929 rs62413974 chr6:113058301 G/T cg09308777 chr6:169852575 NA 0.58 6.06 0.31 3.67e-9 Bipolar disorder (body mass index interaction); LIHC cis rs16958440 0.867 rs28587821 chr18:44687906 G/A cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs8044995 0.563 rs8059585 chr16:68376811 G/A cg05110241 chr16:68378359 PRMT7 -0.84 -9.74 -0.47 6.16e-20 Schizophrenia; LIHC cis rs6684514 1.000 rs12118238 chr1:156235221 G/A cg16558208 chr1:156270281 VHLL 0.52 9.57 0.46 2.2e-19 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs11628318 0.614 rs1190337 chr14:103106159 A/C cg23461800 chr14:103021989 NA -0.41 -5.8 -0.3 1.5e-8 Platelet count; LIHC trans rs3783890 0.943 rs76446292 chr14:93775028 A/C cg02802420 chr16:69363236 PDF;COG8 0.34 6.08 0.31 3.24e-9 Body mass index; LIHC trans rs7618501 1.000 rs9859153 chr3:49807085 G/T cg21582582 chr3:182698605 DCUN1D1 0.52 6.87 0.35 3.02e-11 Intelligence (multi-trait analysis); LIHC trans rs7246657 0.943 rs10417503 chr19:37842735 T/C cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs875971 0.862 rs908915 chr7:65614651 G/T cg11764359 chr7:65958608 NA -0.83 -13.84 -0.6 6.59e-35 Aortic root size; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg11494091 chr17:61959527 GH2 0.44 8.08 0.4 1.15e-14 Prudent dietary pattern; LIHC cis rs4906332 1.000 rs17617094 chr14:103893428 T/C cg19000871 chr14:103996768 TRMT61A -0.46 -7.85 -0.39 5.38e-14 Coronary artery disease; LIHC cis rs2576037 0.899 rs7233515 chr18:44585955 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.48 7.15 0.36 5.34e-12 Personality dimensions; LIHC cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.14 -17.75 -0.69 2e-50 Gut microbiome composition (summer); LIHC cis rs8062405 0.929 rs11864750 chr16:28875204 A/T cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg00990874 chr7:1149470 C7orf50 -0.37 -6.02 -0.31 4.49e-9 Longevity;Endometriosis; LIHC cis rs9527 0.571 rs3740400 chr10:104629465 T/G cg15744005 chr10:104629667 AS3MT -0.42 -9.55 -0.46 2.61e-19 Arsenic metabolism; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg21548464 chr13:50707937 NA 0.45 6.7 0.34 8.58e-11 Longevity; LIHC cis rs2180341 0.782 rs6924274 chr6:127721556 T/A cg27446573 chr6:127587934 RNF146 0.8 13.18 0.58 2.26e-32 Breast cancer; LIHC trans rs12614435 0.512 rs36113194 chr2:179490785 C/T cg14011486 chr1:26737247 LIN28 0.46 6.66 0.34 1.1e-10 Atrial fibrillation; LIHC cis rs10791097 0.694 rs2155749 chr11:130751094 G/T cg14779329 chr11:130786720 SNX19 0.42 6.36 0.33 6.33e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2072438 0.503 rs2146838 chr9:123876305 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.44 -6.17 -0.32 1.96e-9 Rheumatoid arthritis; LIHC cis rs9325144 0.647 rs12227834 chr12:38849246 G/C cg26384229 chr12:38710491 ALG10B -0.56 -7.58 -0.38 3.24e-13 Morning vs. evening chronotype; LIHC cis rs4638749 0.677 rs12611470 chr2:108839349 C/T cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg12205742 chr18:68097929 NA 0.43 6.09 0.31 3.01e-9 Hepatitis; LIHC trans rs7618501 1.000 rs2271960 chr3:49878078 A/G cg21659725 chr3:3221576 CRBN 0.93 18.27 0.7 1.56e-52 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.850 rs62052714 chr16:89857180 T/C cg06558623 chr16:89946397 TCF25 0.84 11.07 0.51 1.52e-24 Skin colour saturation; LIHC cis rs61440199 0.892 rs73818810 chr3:20143380 C/T cg00235661 chr3:20228976 SGOL1 -0.41 -5.84 -0.3 1.23e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs6912958 0.935 rs2179844 chr6:88165773 C/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.19 -0.36 4.01e-12 Monocyte percentage of white cells; LIHC cis rs10751667 0.580 rs7395515 chr11:1005160 C/T ch.11.42038R chr11:967971 AP2A2 0.58 10.99 0.51 2.89e-24 Alzheimer's disease (late onset); LIHC cis rs11077998 0.967 rs4614761 chr17:80505809 C/T cg10255544 chr17:80519551 FOXK2 0.46 8.73 0.43 1.15e-16 Reticulocyte fraction of red cells; LIHC cis rs2952156 0.959 rs2941504 chr17:37830900 A/G cg00129232 chr17:37814104 STARD3 -0.5 -9.2 -0.45 3.62e-18 Asthma; LIHC cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg11663144 chr21:46675770 NA -0.34 -6.32 -0.32 7.99e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs208520 0.690 rs176289 chr6:66766522 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.8 -9.11 -0.44 7.24e-18 Exhaled nitric oxide output; LIHC cis rs758324 0.947 rs10052255 chr5:131173106 C/T cg06307176 chr5:131281290 NA 0.41 5.83 0.3 1.27e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs61861422 0.516 rs12412216 chr10:134393338 C/T cg13441142 chr10:134499734 INPP5A 0.46 6.06 0.31 3.52e-9 Primary sclerosing cholangitis; LIHC cis rs67478160 0.619 rs11160759 chr14:104231542 C/T cg24130564 chr14:104152367 KLC1 -0.35 -5.76 -0.3 1.91e-8 Schizophrenia; LIHC cis rs9611565 0.512 rs5996063 chr22:42168767 G/A cg06634786 chr22:41940651 POLR3H 0.72 7.31 0.37 1.94e-12 Vitiligo; LIHC cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg02290350 chr8:58132656 NA 0.5 9.72 0.47 7.22e-20 Developmental language disorder (linguistic errors); LIHC trans rs804280 0.662 rs11250164 chr8:11610686 C/T cg23218760 chr8:16884364 EFHA2 0.48 6.06 0.31 3.52e-9 Myopia (pathological); LIHC cis rs801193 1.000 rs1553609 chr7:66197139 T/C cg14393609 chr7:65229607 NA 0.36 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg00166722 chr3:10149974 C3orf24 0.51 5.92 0.3 7.85e-9 Alzheimer's disease; LIHC cis rs1371867 0.846 rs1660316 chr8:101333049 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC cis rs2050392 0.894 rs2480277 chr10:30703513 G/T cg25182066 chr10:30743637 MAP3K8 0.47 7.59 0.38 3.02e-13 Inflammatory bowel disease; LIHC trans rs10795130 0.568 rs6601800 chr10:4130066 C/T cg20550677 chr22:43506316 BIK -0.5 -6.09 -0.31 3.07e-9 Sex hormone-binding globulin levels; LIHC cis rs7131987 0.903 rs2194519 chr12:29423583 C/T cg12903224 chr12:29470962 FAR2 0.4 6.4 0.33 5.25e-10 QT interval; LIHC cis rs12497850 0.931 rs28642807 chr3:48926816 A/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.17 0.36 4.76e-12 Parkinson's disease; LIHC cis rs9916302 0.861 rs11078913 chr17:37671714 G/T cg00129232 chr17:37814104 STARD3 -0.41 -6.61 -0.34 1.5e-10 Glomerular filtration rate (creatinine); LIHC cis rs7618501 0.815 rs3819325 chr3:49843723 T/C cg24110177 chr3:50126178 RBM5 -0.43 -6.62 -0.34 1.38e-10 Intelligence (multi-trait analysis); LIHC cis rs787274 1.000 rs787301 chr9:115542737 G/T cg13803584 chr9:115635662 SNX30 0.53 5.82 0.3 1.37e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3849570 0.514 rs4389498 chr3:82015395 G/A cg07356753 chr3:81810745 GBE1 -0.43 -6.54 -0.33 2.28e-10 Waist circumference;Body mass index; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.47 -7.37 -0.37 1.28e-12 Prudent dietary pattern; LIHC cis rs17401966 1.000 rs12402052 chr1:10318652 C/G cg19773385 chr1:10388646 KIF1B -0.48 -8.21 -0.41 4.66e-15 Hepatocellular carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05792022 chr13:41239732 FOXO1 0.47 6.49 0.33 3.02e-10 Lung function (FEV1/FVC); LIHC cis rs6088580 0.634 rs6120666 chr20:33090718 A/G cg08999081 chr20:33150536 PIGU 0.67 13.46 0.59 1.89e-33 Glomerular filtration rate (creatinine); LIHC cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg11890956 chr21:40555474 PSMG1 -1.05 -16.0 -0.65 2.14e-43 Cognitive function; LIHC trans rs2243480 1.000 rs68189316 chr7:65409169 C/G cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs9303401 0.614 rs34683543 chr17:56520036 C/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.92 0.43 2.81e-17 Cognitive test performance; LIHC cis rs1784581 0.500 rs9355379 chr6:162421466 C/T cg17173639 chr6:162384350 PARK2 0.56 8.27 0.41 2.98e-15 Itch intensity from mosquito bite; LIHC cis rs4722404 0.643 rs4722443 chr7:3156031 T/C cg19214707 chr7:3157722 NA 0.36 6.57 0.33 1.86e-10 Atopic dermatitis; LIHC cis rs10870270 0.830 rs11146269 chr10:133761820 G/A cg26149184 chr10:133730230 NA 0.48 7.55 0.38 4.05e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs904251 0.523 rs10947675 chr6:37479972 G/A cg01843034 chr6:37503916 NA -0.46 -7.8 -0.39 7.63e-14 Cognitive performance; LIHC cis rs10751667 0.666 rs11246358 chr11:967349 G/A ch.11.42038R chr11:967971 AP2A2 0.55 9.9 0.47 1.81e-20 Alzheimer's disease (late onset); LIHC cis rs7647973 0.710 rs1491983 chr3:49639803 G/T cg03060546 chr3:49711283 APEH 0.61 6.88 0.35 2.89e-11 Menarche (age at onset); LIHC cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg03188948 chr7:1209495 NA 0.48 6.81 0.35 4.45e-11 Longevity;Endometriosis; LIHC cis rs60871478 0.947 rs62432255 chr7:804219 G/A cg05535760 chr7:792225 HEATR2 0.79 11.27 0.52 2.85e-25 Cerebrospinal P-tau181p levels; LIHC cis rs7613875 0.641 rs2624845 chr3:50062437 C/A cg21467203 chr3:49911342 NA 0.52 9.52 0.46 3.25e-19 Body mass index; LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs911119 1.000 rs2016161 chr20:23621174 G/T cg16589663 chr20:23618590 CST3 -0.78 -8.44 -0.42 9.09e-16 Chronic kidney disease; LIHC cis rs10193935 0.901 rs222464 chr2:42643889 C/T cg27598129 chr2:42591480 NA -0.72 -10.2 -0.48 1.72e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs2952156 1.000 rs2643194 chr17:37853048 C/T cg00129232 chr17:37814104 STARD3 -0.48 -8.67 -0.42 1.75e-16 Asthma; LIHC cis rs3768617 0.811 rs12120747 chr1:183042531 G/A ch.1.3577855R chr1:183094577 LAMC1 0.48 7.65 0.38 2.08e-13 Fuchs's corneal dystrophy; LIHC cis rs7534824 0.582 rs41312670 chr1:101443431 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 7.29 0.37 2.23e-12 Refractive astigmatism; LIHC cis rs778371 0.578 rs2675956 chr2:233753340 G/A cg08000102 chr2:233561755 GIGYF2 -0.71 -10.8 -0.5 1.36e-23 Schizophrenia; LIHC cis rs3849570 1.000 rs7638516 chr3:81826249 A/C cg07356753 chr3:81810745 GBE1 -0.58 -7.88 -0.39 4.46e-14 Waist circumference;Body mass index; LIHC trans rs11098499 0.863 rs3775847 chr4:120447642 A/C cg25214090 chr10:38739885 LOC399744 0.62 10.05 0.48 5.46e-21 Corneal astigmatism; LIHC cis rs2710642 0.611 rs2204655 chr2:62883786 C/T cg17519650 chr2:63277830 OTX1 0.52 7.52 0.38 4.73e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg20119798 chr7:94954144 PON1 -0.46 -8.33 -0.41 2.04e-15 Paraoxonase activity; LIHC cis rs2576037 0.526 rs7240239 chr18:44460037 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.15 -0.36 5.17e-12 Personality dimensions; LIHC cis rs892961 0.867 rs6501955 chr17:75414443 A/G cg05865280 chr17:75406074 SEPT9 0.65 13.41 0.59 3.07e-33 Airflow obstruction; LIHC cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg11890956 chr21:40555474 PSMG1 1.07 15.42 0.64 4.13e-41 Cognitive function; LIHC cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg25072359 chr17:41440525 NA 0.38 5.98 0.31 5.55e-9 Menopause (age at onset); LIHC cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg00106254 chr7:1943704 MAD1L1 -0.43 -6.9 -0.35 2.55e-11 Bipolar disorder and schizophrenia; LIHC cis rs8005677 1.000 rs1043209 chr14:23373986 A/G cg07971674 chr14:23388846 RBM23 0.41 5.96 0.31 6.23e-9 Cognitive ability (multi-trait analysis); LIHC trans rs1814175 0.817 rs7927373 chr11:49957640 A/C cg03929089 chr4:120376271 NA -0.89 -18.22 -0.7 2.49e-52 Height; LIHC cis rs17433710 0.516 rs6691289 chr1:162644912 G/A cg01063088 chr1:162760584 HSD17B7 0.44 6.09 0.31 3.11e-9 Dupuytren's disease; LIHC cis rs3741151 0.773 rs73542938 chr11:73103012 G/C cg17517138 chr11:73019481 ARHGEF17 0.81 5.81 0.3 1.4e-8 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg21724239 chr8:58056113 NA 0.49 6.45 0.33 3.86e-10 Developmental language disorder (linguistic errors); LIHC trans rs2243480 1.000 rs9769882 chr7:65642925 T/C cg10756647 chr7:56101905 PSPH -1.08 -13.21 -0.58 1.83e-32 Diabetic kidney disease; LIHC cis rs1865760 0.516 rs9295684 chr6:26069669 T/C cg18357526 chr6:26021779 HIST1H4A 0.48 6.98 0.35 1.58e-11 Height; LIHC cis rs611744 0.608 rs667742 chr8:109254003 T/C cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs6062302 0.549 rs4809586 chr20:62249402 C/T cg06363034 chr20:62225388 GMEB2 -0.45 -7.71 -0.38 1.4e-13 Glioblastoma; LIHC cis rs2153535 0.580 rs6921036 chr6:8455400 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.78 0.43 8.18e-17 Motion sickness; LIHC cis rs7312933 0.592 rs1551210 chr12:42865874 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.92 0.39 3.38e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs10213084 0.920 rs6835151 chr4:147529209 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.47 6.76 0.34 5.98e-11 Heart rate; LIHC cis rs12908161 1.000 rs56864281 chr15:85357649 C/A cg12863693 chr15:85201151 NMB 0.44 6.12 0.31 2.56e-9 Schizophrenia; LIHC cis rs2797160 0.967 rs2797159 chr6:126009557 G/A cg05901451 chr6:126070800 HEY2 0.45 7.44 0.37 8.16e-13 Endometrial cancer; LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs6570726 0.526 rs72994723 chr6:145722948 G/A cg23711669 chr6:146136114 FBXO30 -0.35 -5.81 -0.3 1.44e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 0.958 rs12143044 chr1:67460054 A/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.94 0.57 1.88e-31 Prudent dietary pattern; LIHC cis rs9296092 0.538 rs9461880 chr6:33518714 C/T cg13560919 chr6:33536144 NA -0.39 -6.3 -0.32 8.94e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs11229555 0.874 rs12800710 chr11:58314540 C/T cg15696309 chr11:58395628 NA -0.72 -8.86 -0.43 4.33e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs74181299 0.525 rs4671119 chr2:65362211 C/G cg05010058 chr2:65284262 CEP68 -0.36 -5.72 -0.3 2.36e-8 Pulse pressure; LIHC cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg02951883 chr7:2050386 MAD1L1 -0.62 -9.59 -0.46 1.88e-19 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.966 rs2062278 chr3:47416761 C/T cg16586182 chr3:47516702 SCAP -0.6 -11.81 -0.54 3.08e-27 Colorectal cancer; LIHC cis rs11971779 0.680 rs10265718 chr7:139100068 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs1008375 0.932 rs6844593 chr4:17659039 T/C cg02297831 chr4:17616191 MED28 0.43 6.12 0.31 2.6e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2629540 0.847 rs10901807 chr10:126384610 G/A cg20435097 chr10:126320824 FAM53B -0.42 -6.25 -0.32 1.21e-9 Cocaine dependence; LIHC cis rs926392 0.547 rs6129161 chr20:37678327 T/G cg16355469 chr20:37678765 NA 0.53 8.57 0.42 3.58e-16 Dialysis-related mortality; LIHC cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg20090690 chr10:134436459 INPP5A 0.46 5.86 0.3 1.12e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.76 -0.3 1.84e-8 Total body bone mineral density; LIHC cis rs9902453 1.000 rs59274738 chr17:28437635 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.88 0.47 2.03e-20 Coffee consumption (cups per day); LIHC cis rs7772486 0.875 rs7739418 chr6:146359188 G/A cg23711669 chr6:146136114 FBXO30 0.59 10.42 0.49 2.88e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs1843834 0.931 rs10170573 chr2:225552916 A/G cg22509189 chr2:225307070 NA -0.55 -6.81 -0.35 4.28e-11 IgE levels in asthmatics (D.p. specific); LIHC cis rs60871478 0.578 rs62432900 chr7:826794 G/C cg05535760 chr7:792225 HEATR2 0.97 13.44 0.59 2.33e-33 Cerebrospinal P-tau181p levels; LIHC trans rs12478296 1.000 rs73007138 chr2:243007041 C/T cg01596870 chr19:55963115 NA -0.62 -6.91 -0.35 2.37e-11 Obesity-related traits; LIHC trans rs8073060 0.544 rs225249 chr17:33942540 T/C cg19694781 chr19:47549865 TMEM160 -1.25 -13.43 -0.59 2.45e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs507080 0.769 rs11603616 chr11:118496066 G/A cg04173919 chr11:118528438 PHLDB1 0.32 5.79 0.3 1.58e-8 Serum metabolite levels; LIHC cis rs9902453 0.904 rs55866125 chr17:28312993 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 14.23 0.61 1.99e-36 Coffee consumption (cups per day); LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg09417038 chr21:47716443 C21orf57 -0.59 -9.07 -0.44 9.17e-18 Testicular germ cell tumor; LIHC trans rs1005277 0.579 rs2472173 chr10:38374638 G/A cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs6089584 0.528 rs4925335 chr20:60627034 G/A cg23262073 chr20:60523788 NA -0.28 -5.78 -0.3 1.65e-8 Body mass index; LIHC cis rs7312933 0.898 rs10880221 chr12:42384589 C/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.44 6.35 0.32 6.93e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs17253792 0.822 rs79538158 chr14:56051365 G/T cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.15e-10 Putamen volume; LIHC cis rs17685 0.535 rs41296542 chr7:75600008 A/G cg16684958 chr7:75615977 POR 0.41 6.23 0.32 1.37e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2197308 0.692 rs67352173 chr12:37906912 A/T cg26384229 chr12:38710491 ALG10B 0.81 10.43 0.49 2.66e-22 Morning vs. evening chronotype; LIHC cis rs34172651 0.917 rs2343606 chr16:24793741 C/T cg00152838 chr16:24741724 TNRC6A -0.48 -6.34 -0.32 7.14e-10 Intelligence (multi-trait analysis); LIHC cis rs796364 1.000 rs281788 chr2:200783705 A/T cg23649088 chr2:200775458 C2orf69 0.5 6.11 0.31 2.74e-9 Schizophrenia; LIHC cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg02290350 chr8:58132656 NA 0.5 8.99 0.44 1.74e-17 Developmental language disorder (linguistic errors); LIHC trans rs11246602 1 rs11246602 chr11:51512090 T/C cg15704280 chr7:45808275 SEPT13 0.64 6.2 0.32 1.58e-9 HDL cholesterol levels;HDL cholesterol; LIHC cis rs754466 0.651 rs56138814 chr10:79625795 T/C cg17075019 chr10:79541650 NA -0.75 -11.49 -0.53 4.54e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs10506458 0.915 rs17738485 chr12:63394932 T/C cg22491629 chr6:157744540 C6orf35 -0.61 -11.0 -0.51 2.6e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 -0.47 -6.53 -0.33 2.38e-10 Mean platelet volume; LIHC cis rs1005277 0.528 rs2057228 chr10:38515766 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs13161895 1.000 rs6873994 chr5:179436696 T/G cg02702477 chr5:179499311 RNF130 -0.75 -10.29 -0.49 7.91e-22 LDL cholesterol; LIHC cis rs933688 1.000 rs9293568 chr5:90737845 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.39 0.66 5.8e-45 Smoking behavior; LIHC cis rs12908161 1.000 rs12912388 chr15:85344550 T/A cg12863693 chr15:85201151 NMB 0.44 6.34 0.32 7.18e-10 Schizophrenia; LIHC trans rs2262909 0.962 rs73019889 chr19:22277826 C/G cg05197062 chr11:11642011 GALNTL4 0.45 6.61 0.34 1.48e-10 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2404602 0.647 rs12910820 chr15:77022825 T/C cg23625390 chr15:77176239 SCAPER -0.55 -9.23 -0.45 2.94e-18 Blood metabolite levels; LIHC cis rs10461617 0.592 rs6450403 chr5:56062737 A/C cg12311346 chr5:56204834 C5orf35 -0.56 -7.77 -0.39 9.32e-14 Type 2 diabetes; LIHC cis rs7927592 0.956 rs7102273 chr11:68385579 T/C cg01657329 chr11:68192670 LRP5 -0.48 -6.29 -0.32 9.92e-10 Total body bone mineral density; LIHC cis rs10791323 0.519 rs329663 chr11:133754543 A/G cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.55e-9 Childhood ear infection; LIHC cis rs919433 0.726 rs11904247 chr2:198238424 T/G cg10820045 chr2:198174542 NA 0.55 8.73 0.43 1.13e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs911555 0.504 rs745079 chr14:104073551 G/A cg24130564 chr14:104152367 KLC1 -0.65 -12.09 -0.55 3.04e-28 Intelligence (multi-trait analysis); LIHC cis rs3762637 1.000 rs7615930 chr3:122125750 G/T cg24169773 chr3:122142474 KPNA1 -0.45 -8.79 -0.43 7.44e-17 LDL cholesterol levels; LIHC cis rs3106136 0.967 rs13135934 chr4:95207688 G/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.9 -0.39 3.77e-14 Capecitabine sensitivity; LIHC cis rs903552 0.800 rs12903584 chr15:101999369 G/A cg06707286 chr15:102010195 PCSK6 -0.42 -6.02 -0.31 4.4e-9 Diabetic kidney disease; LIHC cis rs796364 0.806 rs34381014 chr2:200916403 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs9611519 0.894 rs4821990 chr22:41438710 A/C cg03806693 chr22:41940476 POLR3H -0.73 -8.31 -0.41 2.22e-15 Neuroticism; LIHC cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg04727924 chr7:799746 HEATR2 0.41 6.27 0.32 1.07e-9 Perceived unattractiveness to mosquitoes; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg00280220 chr17:61926910 NA 0.42 6.79 0.34 4.88e-11 Prudent dietary pattern; LIHC trans rs7615952 0.512 rs34085484 chr3:125544186 T/C cg07211511 chr3:129823064 LOC729375 -0.49 -7.59 -0.38 3.02e-13 Blood pressure (smoking interaction); LIHC cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs2066819 1.000 rs59295315 chr12:56708576 G/A cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs1538970 0.748 rs11211137 chr1:46013892 T/A cg24296786 chr1:45957014 TESK2 -0.49 -6.38 -0.33 5.64e-10 Platelet count; LIHC cis rs6964587 0.839 rs13229273 chr7:91444472 G/A cg17063962 chr7:91808500 NA 0.96 17.6 0.69 8.27e-50 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00292435 chr9:91925643 CKS2 0.46 6.51 0.33 2.6e-10 Pancreatic cancer; LIHC cis rs9911578 1.000 rs9892062 chr17:56976981 G/A cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20930618 chr1:151162157 VPS72 0.39 6.05 0.31 3.82e-9 Pancreatic cancer; LIHC cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg27121462 chr16:89883253 FANCA 0.42 6.44 0.33 3.93e-10 Vitiligo; LIHC cis rs826838 0.967 rs1684413 chr12:39128704 G/A cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs4755351 0.553 rs11032165 chr11:33164117 A/G cg05567920 chr11:33183001 CSTF3 0.42 6.21 0.32 1.56e-9 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01839850 chr22:38240395 ANKRD54;MIR658 0.48 7.4 0.37 1.04e-12 Pancreatic cancer; LIHC cis rs2242116 0.796 rs2290546 chr3:46965197 C/G cg02527881 chr3:46936655 PTH1R -0.45 -9.12 -0.44 6.8e-18 Birth weight; LIHC cis rs2439831 0.850 rs3097773 chr15:43893072 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.65 -10.05 -0.48 5.34e-21 Lung cancer in ever smokers; LIHC cis rs6121246 0.738 rs6121242 chr20:30410877 T/C cg13852791 chr20:30311386 BCL2L1 0.9 9.36 0.45 1.12e-18 Mean corpuscular hemoglobin; LIHC cis rs6912958 0.781 rs985764 chr6:88215206 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.05 -0.4 1.35e-14 Monocyte percentage of white cells; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16800975 chr8:17434541 PDGFRL 0.44 6.58 0.34 1.79e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs311392 0.554 rs689591 chr8:55096050 A/G cg20636351 chr8:55087400 NA -0.36 -7.31 -0.37 1.87e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs12142240 0.628 rs56126529 chr1:46808860 C/T cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs1707322 0.717 rs3014245 chr1:46086913 C/T cg24296786 chr1:45957014 TESK2 0.4 5.74 0.3 2.04e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6424115 1.000 rs34477640 chr1:24154067 T/C cg10978503 chr1:24200527 CNR2 -0.38 -8.97 -0.44 2.02e-17 Immature fraction of reticulocytes; LIHC cis rs7520050 0.902 rs4638056 chr1:46458153 T/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 6.02 0.31 4.5e-9 Red blood cell count;Reticulocyte count; LIHC trans rs1005277 0.540 rs2474598 chr10:38430296 C/T cg17830980 chr10:43048298 ZNF37B 0.55 11.16 0.52 7.14e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9534288 0.699 rs4280137 chr13:46664008 G/A cg15192986 chr13:46630673 CPB2 -0.42 -6.1 -0.31 2.87e-9 Blood protein levels; LIHC cis rs12586317 0.547 rs4982236 chr14:35468046 C/G cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.03e-32 Psoriasis; LIHC trans rs10213084 1.000 rs13113553 chr4:147494348 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs7617773 0.780 rs9846818 chr3:48375685 C/T cg11946769 chr3:48343235 NME6 0.65 8.98 0.44 1.81e-17 Coronary artery disease; LIHC trans rs11148252 0.875 rs9568728 chr13:52946593 C/T cg18335740 chr13:41363409 SLC25A15 0.38 6.6 0.34 1.57e-10 Lewy body disease; LIHC cis rs1005277 0.522 rs289650 chr10:37975505 G/T cg00409905 chr10:38381863 ZNF37A -0.51 -9.22 -0.45 3.07e-18 Extrinsic epigenetic age acceleration; LIHC cis rs9942416 0.660 rs61173369 chr5:74997995 A/G cg19683494 chr5:74908142 NA 0.58 7.71 0.38 1.4e-13 Age-related disease endophenotypes; LIHC cis rs72781680 0.848 rs56021814 chr2:24073437 T/A cg08917208 chr2:24149416 ATAD2B 0.85 8.12 0.4 8.32e-15 Lymphocyte counts; LIHC cis rs1801251 0.727 rs13029336 chr2:233569935 A/G cg08000102 chr2:233561755 GIGYF2 -0.73 -11.88 -0.54 1.72e-27 Coronary artery disease; LIHC cis rs6426558 0.502 rs2813970 chr1:227410637 C/T cg10327440 chr1:227177885 CDC42BPA 0.39 6.02 0.31 4.39e-9 Neutrophil percentage of white cells; LIHC cis rs3806843 1.000 rs2098058 chr5:140157427 A/C cg19875535 chr5:140030758 IK -0.37 -6.1 -0.31 2.86e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9814567 1.000 rs4498009 chr3:134198008 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.7 -12.43 -0.56 1.53e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9303401 0.659 rs7216648 chr17:56790858 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs600806 0.888 rs3879450 chr1:109909149 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC trans rs637571 0.522 rs12792888 chr11:65761446 C/T cg17712092 chr4:129076599 LARP1B 0.74 12.98 0.57 1.38e-31 Eosinophil percentage of white cells; LIHC cis rs2836950 0.545 rs2836922 chr21:40516308 C/T cg11890956 chr21:40555474 PSMG1 -0.46 -7.48 -0.38 6.21e-13 Menarche (age at onset); LIHC cis rs7927771 0.965 rs11039416 chr11:47846711 G/A cg20135002 chr11:47629003 NA -0.53 -9.01 -0.44 1.47e-17 Subjective well-being; LIHC cis rs4853012 0.887 rs6737314 chr2:74339586 A/G cg23149560 chr2:74406255 MOBKL1B 0.44 6.18 0.32 1.86e-9 Gestational age at birth (maternal effect); LIHC cis rs6762477 0.748 rs3755831 chr3:50228767 G/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.48 -6.75 -0.34 6.39e-11 Menarche (age at onset); LIHC cis rs7940866 0.745 rs1368853 chr11:130866084 A/G cg12179176 chr11:130786555 SNX19 0.64 9.16 0.44 5.06e-18 Schizophrenia; LIHC cis rs801193 0.548 rs2659904 chr7:66178602 C/A cg12463550 chr7:65579703 CRCP 0.43 6.11 0.31 2.71e-9 Aortic root size; LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.967 rs2911257 chr16:89484134 C/G cg06640241 chr16:89574553 SPG7 0.66 10.7 0.5 3e-23 Multiple myeloma (IgH translocation); LIHC cis rs35110281 0.811 rs2838337 chr21:45072621 A/C cg21573476 chr21:45109991 RRP1B -0.55 -10.54 -0.5 1.12e-22 Mean corpuscular volume; LIHC cis rs35160687 0.623 rs11127019 chr2:86467618 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 0.4 6.45 0.33 3.91e-10 Night sleep phenotypes; LIHC cis rs6088580 0.634 rs6088475 chr20:32964987 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.22e-33 Glomerular filtration rate (creatinine); LIHC cis rs10489202 0.954 rs11586522 chr1:168091031 G/T cg17859187 chr1:168147929 TIPRL 0.52 6.96 0.35 1.7e-11 Schizophrenia; LIHC cis rs66573146 1.000 rs55833486 chr4:6978729 C/A cg15105060 chr4:7024189 TBC1D14 -0.72 -6.04 -0.31 3.96e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2019960 0.679 rs2648846 chr8:129179990 A/G cg15331705 chr8:129180010 NA -0.38 -6.98 -0.35 1.55e-11 Hodgkin's lymphoma;Multiple sclerosis; LIHC cis rs11690935 0.655 rs1028127 chr2:172530036 T/C cg13550731 chr2:172543902 DYNC1I2 0.63 11.39 0.52 1.08e-25 Schizophrenia; LIHC cis rs2281845 0.507 rs12025414 chr1:201100496 A/G cg06714761 chr1:201096289 NA 0.35 5.97 0.31 5.82e-9 Permanent tooth development; LIHC cis rs1059312 0.778 rs4760594 chr12:129296865 T/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.77 -16.8 -0.67 1.3e-46 Systemic lupus erythematosus; LIHC trans rs6598955 0.671 rs57386998 chr1:26569821 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.81 -9.1 -0.44 7.57e-18 Obesity-related traits; LIHC cis rs3796352 1.000 rs35737577 chr3:53002557 G/C cg04865290 chr3:52927548 TMEM110 -0.51 -5.9 -0.3 8.82e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs9399135 0.933 rs28384512 chr6:135376232 C/T cg24558204 chr6:135376177 HBS1L 0.42 6.76 0.34 5.96e-11 Red blood cell count; LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg21782813 chr7:2030301 MAD1L1 0.5 8.71 0.43 1.29e-16 Bipolar disorder and schizophrenia; LIHC cis rs1355223 0.867 rs1377495 chr11:34682962 A/C cg11058730 chr11:34937778 PDHX;APIP 0.43 5.91 0.3 8.18e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7872515 0.887 rs10992234 chr9:94877836 A/G cg01248375 chr9:94877805 SPTLC1 0.54 8.16 0.4 6.26e-15 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC cis rs651907 0.535 rs13085776 chr3:101505507 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 10.52 0.49 1.29e-22 Colorectal cancer; LIHC cis rs3617 0.573 rs13072537 chr3:52896032 C/A cg11645453 chr3:52864694 ITIH4 0.22 5.75 0.3 1.98e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9443189 0.950 rs6938349 chr6:76484280 A/T cg01950844 chr6:76311363 SENP6 0.48 5.77 0.3 1.8e-8 Prostate cancer; LIHC cis rs17253792 0.731 rs74823888 chr14:56049800 T/C cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs2576037 0.583 rs504668 chr18:44410749 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.89 -0.3 9.25e-9 Personality dimensions; LIHC cis rs7027203 0.828 rs4344139 chr9:96600298 T/C cg14598338 chr9:96623480 NA -0.33 -6.57 -0.33 1.86e-10 DNA methylation (variation); LIHC cis rs875971 0.540 rs35510581 chr7:65578777 G/A cg11764359 chr7:65958608 NA -0.65 -8.93 -0.43 2.76e-17 Aortic root size; LIHC cis rs909341 0.909 rs2427530 chr20:62361737 G/A cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.74e-11 Atopic dermatitis; LIHC cis rs273218 1.000 rs156380 chr5:53378450 T/C ch.5.1024479R chr5:53302184 ARL15 0.64 9.96 0.47 1.07e-20 Migraine; LIHC cis rs12824058 0.831 rs11609362 chr12:130810526 T/C cg24838063 chr12:130822603 PIWIL1 0.67 9.96 0.47 1.1e-20 Menopause (age at onset); LIHC cis rs17095355 1.000 rs7921609 chr10:111691599 G/A cg00817464 chr10:111662876 XPNPEP1 -0.42 -6.17 -0.32 1.9e-9 Biliary atresia; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg22963979 chr7:1858916 MAD1L1 -0.46 -7.66 -0.38 1.97e-13 Bipolar disorder and schizophrenia; LIHC cis rs6466055 0.720 rs1121194 chr7:104981133 T/C cg04380332 chr7:105027541 SRPK2 0.35 6.62 0.34 1.38e-10 Schizophrenia; LIHC cis rs651907 0.535 rs11712309 chr3:101519097 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs6933660 0.745 rs6557138 chr6:151732017 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.54 -8.24 -0.41 3.75e-15 Menarche (age at onset); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg24866320 chr6:158703163 NA -0.25 -6.21 -0.32 1.56e-9 Calcium levels; LIHC cis rs6582630 0.519 rs11495700 chr12:38288240 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.73 0.3 2.21e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs765787 0.530 rs4774550 chr15:45542312 C/T cg26924012 chr15:45694286 SPATA5L1 -0.39 -6.09 -0.31 2.99e-9 Uric acid levels; LIHC cis rs8180040 0.726 rs9843075 chr3:47195630 A/G cg16586182 chr3:47516702 SCAP -0.46 -7.8 -0.39 7.62e-14 Colorectal cancer; LIHC cis rs7647973 1.000 rs2177268 chr3:49439725 A/T cg07636037 chr3:49044803 WDR6 -0.53 -6.44 -0.33 4.07e-10 Menarche (age at onset); LIHC cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg03517284 chr6:25882590 NA -0.64 -8.98 -0.44 1.8e-17 Blood metabolite levels; LIHC cis rs7772486 0.641 rs2748489 chr6:146331287 T/G cg23711669 chr6:146136114 FBXO30 0.58 8.84 0.43 5.32e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs17345786 0.906 rs11710016 chr3:101120030 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.52 -6.45 -0.33 3.73e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs68170813 0.559 rs6971675 chr7:106833797 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.3e-9 Coronary artery disease; LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg10134156 chr14:77732494 MIR1260;NGB -0.38 -6.27 -0.32 1.08e-9 Mild influenza (H1N1) infection; LIHC cis rs79149102 0.579 rs76900720 chr15:75348895 A/T cg15902774 chr15:75289873 SCAMP5 0.45 6.52 0.33 2.49e-10 Lung cancer; LIHC cis rs10911251 0.546 rs2027085 chr1:183108611 G/T ch.1.3577855R chr1:183094577 LAMC1 -0.59 -10.26 -0.48 1.08e-21 Colorectal cancer; LIHC cis rs11628318 0.564 rs8013957 chr14:103140254 C/T cg01864069 chr14:103024347 NA 0.36 5.94 0.31 7.16e-9 Platelet count; LIHC cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg21280719 chr6:42927975 GNMT -0.31 -7.0 -0.35 1.36e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7937890 0.869 rs2915404 chr11:14404825 A/G cg22961513 chr11:14280813 SPON1 -0.44 -6.6 -0.34 1.54e-10 Mitochondrial DNA levels; LIHC cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg00684032 chr4:1343700 KIAA1530 0.5 7.3 0.37 2.01e-12 Obesity-related traits; LIHC cis rs2295359 1.000 rs736197 chr1:67607135 G/T cg12940439 chr1:67600707 NA 0.39 7.04 0.36 1.04e-11 Psoriasis; LIHC cis rs7613875 0.600 rs1061474 chr3:50144951 T/C cg21467203 chr3:49911342 NA 0.5 9.2 0.45 3.71e-18 Body mass index; LIHC cis rs7959452 0.530 rs12811632 chr12:69755003 G/A cg22834771 chr12:69754056 YEATS4 -0.52 -9.26 -0.45 2.36e-18 Blood protein levels; LIHC cis rs7208859 0.623 rs6505207 chr17:29076571 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26764764 chr17:79077412 BAIAP2 -0.39 -6.42 -0.33 4.49e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs5995875 0.556 rs73171007 chr22:41049101 A/G cg14879645 chr22:41048474 NA 0.4 5.82 0.3 1.35e-8 Breast size; LIHC cis rs710865 1.000 rs710866 chr1:19568722 G/C cg13387374 chr1:19411106 UBR4 0.42 6.48 0.33 3.14e-10 Brain structure; LIHC cis rs6456156 0.586 rs6456154 chr6:167472256 C/T cg07741184 chr6:167504864 NA 0.29 6.86 0.35 3.3e-11 Primary biliary cholangitis; LIHC cis rs6951245 0.507 rs11976805 chr7:1138716 C/T cg04025307 chr7:1156635 C7orf50 0.5 6.72 0.34 7.79e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12402495 chr1:154192844 C1orf43;UBAP2L 0.43 6.75 0.34 6.29e-11 Cognitive function; LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.72 0.39 1.27e-13 Prudent dietary pattern; LIHC cis rs11105298 0.891 rs11105319 chr12:89927177 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.63 -7.07 -0.36 8.54e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs11112613 0.713 rs871220 chr12:105938558 G/A cg03607813 chr12:105948248 NA 0.65 12.51 0.56 7.71e-30 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7119 0.717 rs11629652 chr15:77779951 C/A cg17802220 chr15:77601643 NA -0.4 -6.9 -0.35 2.52e-11 Type 2 diabetes; LIHC cis rs9359856 0.510 rs6937789 chr6:90468775 C/G cg13799429 chr6:90582589 CASP8AP2 0.79 8.93 0.43 2.68e-17 Bipolar disorder; LIHC cis rs9534288 0.797 rs7996875 chr13:46612836 C/T cg15192986 chr13:46630673 CPB2 0.52 8.31 0.41 2.27e-15 Blood protein levels; LIHC cis rs1707322 0.752 rs61784793 chr1:46149285 G/A cg03146154 chr1:46216737 IPP 0.58 9.62 0.46 1.5700000000000001e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7618501 1.000 rs695238 chr3:49869158 A/C cg21665057 chr3:196295764 WDR53;FBXO45 0.8 14.65 0.62 4.81e-38 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.966 rs785492 chr1:46583607 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.9 0.3 8.86e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6952808 0.823 rs10950448 chr7:1966492 G/C cg02951883 chr7:2050386 MAD1L1 -0.64 -9.98 -0.47 9.65e-21 Bipolar disorder and schizophrenia; LIHC cis rs7589728 0.514 rs12465706 chr2:88467459 C/A cg04511125 chr2:88470314 THNSL2 0.98 9.98 0.47 9.25e-21 Plasma clusterin levels; LIHC cis rs2834188 1.000 rs1018742 chr21:34686381 A/G cg04842828 chr21:34696676 IFNAR1 0.44 5.98 0.31 5.73e-9 Narcolepsy; LIHC cis rs72781680 0.611 rs74661620 chr2:24365260 C/A cg06627628 chr2:24431161 ITSN2 -0.63 -7.2 -0.36 3.96e-12 Lymphocyte counts; LIHC cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg09222892 chr1:25734099 RHCE 0.48 8.89 0.43 3.55e-17 Erythrocyte sedimentation rate; LIHC cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg03806693 chr22:41940476 POLR3H 0.98 10.47 0.49 1.98e-22 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10838687 0.800 rs10838686 chr11:47311367 G/T cg26139080 chr11:47293733 MADD -0.41 -5.77 -0.3 1.73e-8 Proinsulin levels; LIHC trans rs6912958 0.712 rs4498321 chr6:88339251 G/C cg23605328 chr1:201951606 RNPEP 0.39 6.2 0.32 1.66e-9 Monocyte percentage of white cells; LIHC cis rs4924935 0.851 rs12936834 chr17:18807078 A/G cg26378065 chr17:18585709 ZNF286B 0.48 5.79 0.3 1.61e-8 Pancreatic cancer; LIHC cis rs9326248 0.953 rs634960 chr11:117072963 T/C cg10130564 chr11:117069849 TAGLN -0.37 -6.21 -0.32 1.51e-9 Blood protein levels; LIHC cis rs748404 0.631 rs11070399 chr15:43646347 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.56 10.0 0.48 8.23e-21 Lung cancer; LIHC cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg08499158 chr17:42289980 UBTF -0.49 -7.99 -0.4 2.15e-14 Total body bone mineral density; LIHC cis rs6988636 0.536 rs16898043 chr8:124155886 A/G cg15893493 chr8:124194847 FAM83A 0.81 7.25 0.37 2.74e-12 Urinary uromodulin levels; LIHC cis rs9914988 0.778 rs35398767 chr17:27122960 A/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs9910055 0.529 rs228746 chr17:42173752 T/C cg19774624 chr17:42201019 HDAC5 0.5 6.0 0.31 5.01e-9 Total body bone mineral density; LIHC cis rs35883536 0.626 rs80052576 chr1:101039229 A/G cg14515779 chr1:101123966 NA 0.43 6.09 0.31 3.05e-9 Monocyte count; LIHC trans rs60843830 0.662 rs6721594 chr2:305203 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 -0.66 -10.17 -0.48 2.2e-21 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs1550582 1.000 rs62523710 chr8:135538773 T/C cg17885191 chr8:135476712 NA 0.37 6.15 0.32 2.21e-9 Educational attainment; LIHC cis rs4819052 0.851 rs2838858 chr21:46681093 T/A cg22633049 chr21:46681294 NA -0.36 -6.15 -0.32 2.1e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2439831 0.850 rs28513374 chr15:44125495 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.73 0.34 7.11e-11 Lung cancer in ever smokers; LIHC cis rs7772486 0.632 rs9386128 chr6:146049053 G/A cg13319975 chr6:146136371 FBXO30 0.34 5.72 0.3 2.29e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2573652 1.000 rs2573625 chr15:100513158 A/G cg09918751 chr15:100517450 ADAMTS17 0.73 12.2 0.55 1.18e-28 Height; LIHC cis rs611744 0.934 rs673356 chr8:109185159 A/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs6461049 0.765 rs1476887 chr7:2151633 T/C cg20295408 chr7:1910781 MAD1L1 -0.42 -6.21 -0.32 1.54e-9 Schizophrenia; LIHC cis rs12497850 0.931 rs6446196 chr3:49004723 A/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.15 0.36 5.31e-12 Parkinson's disease; LIHC trans rs2243480 1.000 rs316322 chr7:65611233 G/C cg10756647 chr7:56101905 PSPH 1.1 13.4 0.59 3.2e-33 Diabetic kidney disease; LIHC cis rs9788682 1.000 rs12438181 chr15:78812098 G/A cg06917634 chr15:78832804 PSMA4 -0.52 -7.34 -0.37 1.58e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs4819052 0.679 rs28623526 chr21:46712324 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.51 7.5 0.38 5.38e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4919087 0.532 rs7068063 chr10:99083968 C/T cg25902810 chr10:99078978 FRAT1 -0.59 -6.88 -0.35 2.82e-11 Monocyte count; LIHC cis rs7715806 0.500 rs17649350 chr5:75006156 C/T cg19683494 chr5:74908142 NA -0.68 -7.81 -0.39 7.06e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6669384 0.774 rs4844622 chr1:208034329 C/T cg22525895 chr1:207977042 MIR29B2 -0.54 -5.96 -0.31 6.45e-9 Immune response to measles vaccine (measles-specific neutralising antibody titre); LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg20007465 chr7:1068125 C7orf50 0.44 6.06 0.31 3.53e-9 Triglycerides; LIHC cis rs7095607 0.560 rs10997955 chr10:69914664 C/T cg18986048 chr10:69913749 MYPN 0.41 6.04 0.31 3.95e-9 Lung function (FVC); LIHC cis rs11190604 1.000 rs4919471 chr10:102299239 A/G cg07080220 chr10:102295463 HIF1AN 0.56 8.09 0.4 1.09e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1552244 0.882 rs13075842 chr3:10055813 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.53 -0.49 1.17e-22 Alzheimer's disease; LIHC cis rs3761218 1.000 rs3761218 chr20:3776175 A/G cg25011176 chr20:3776985 CDC25B 0.46 6.48 0.33 3.21e-10 Bipolar disorder; LIHC cis rs986417 0.748 rs8019541 chr14:60929145 A/G cg27398547 chr14:60952738 C14orf39 0.81 9.56 0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg20887711 chr4:1340912 KIAA1530 -0.48 -7.37 -0.37 1.32e-12 Obesity-related traits; LIHC cis rs2580764 0.632 rs2588510 chr2:55199248 A/G cg09592903 chr2:55203963 RTN4 -0.76 -14.0 -0.6 1.64e-35 Mean platelet volume; LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg18765753 chr7:1198926 ZFAND2A -0.43 -6.06 -0.31 3.58e-9 Bronchopulmonary dysplasia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25750404 chr12:6579648 VAMP1 0.45 6.2 0.32 1.63e-9 Pancreatic cancer; LIHC cis rs7635838 0.684 rs2606757 chr3:11358163 T/A cg00170343 chr3:11313890 ATG7 0.61 10.38 0.49 4.09e-22 HDL cholesterol; LIHC cis rs919433 0.963 rs7582736 chr2:198170342 A/G cg03934865 chr2:198174659 NA -0.57 -9.1 -0.44 7.61e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6459788 0.692 rs10807645 chr7:157258979 T/C cg17306686 chr7:157230923 NA -0.28 -5.79 -0.3 1.58e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs754466 0.706 rs7099526 chr10:79657705 C/G cg17075019 chr10:79541650 NA -0.66 -9.37 -0.45 1.03e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12980942 0.748 rs67511749 chr19:41825158 A/G cg25627403 chr19:41769009 HNRNPUL1 0.47 5.88 0.3 9.65e-9 Coronary artery disease; LIHC cis rs8177179 0.967 rs4443173 chr3:133439378 A/G cg16262614 chr3:133464971 TF 0.45 10.13 0.48 2.79e-21 Iron status biomarkers (transferrin levels); LIHC cis rs1552244 0.554 rs6443275 chr3:10008819 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -7.84 -0.39 5.88e-14 Alzheimer's disease; LIHC cis rs9513627 0.920 rs16956607 chr13:100120220 A/G cg25919922 chr13:100150906 NA -0.78 -7.02 -0.35 1.19e-11 Obesity-related traits; LIHC cis rs5769765 1.000 rs5769760 chr22:50259696 A/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10802521 chr3:52805072 NEK4 -0.5 -6.99 -0.35 1.43e-11 Systolic blood pressure; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18513200 chr4:13629548 BOD1L 0.43 6.13 0.31 2.41e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg08888203 chr3:10149979 C3orf24 0.51 6.21 0.32 1.56e-9 Alzheimer's disease; LIHC cis rs7666738 0.830 rs28417716 chr4:98864859 C/T cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs7909074 1.000 rs7079573 chr10:45400406 G/A cg04218760 chr10:45406644 TMEM72 -0.24 -7.35 -0.37 1.47e-12 Mean corpuscular volume; LIHC cis rs1448094 0.512 rs12297441 chr12:86233980 C/T cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.09e-9 Major depressive disorder; LIHC cis rs1018836 0.828 rs4140679 chr8:91584269 A/C cg16814680 chr8:91681699 NA -0.57 -8.98 -0.44 1.83e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs5769765 0.954 rs5770707 chr22:50244533 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.67 8.85 0.43 4.92e-17 Schizophrenia; LIHC cis rs4718428 0.705 rs13231140 chr7:66361618 C/G cg12165864 chr7:66369176 NA -0.47 -6.82 -0.35 4.17e-11 Corneal structure; LIHC cis rs2421770 0.504 rs7943314 chr11:35363823 A/G cg13971030 chr11:35366721 SLC1A2 -0.43 -7.31 -0.37 1.93e-12 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs6840360 1.000 rs2840130 chr4:152600699 T/C cg22705602 chr4:152727874 NA -0.28 -6.0 -0.31 4.9e-9 Intelligence (multi-trait analysis); LIHC cis rs739401 0.611 rs10833048 chr11:3020040 A/G cg05729581 chr11:3078854 CARS -0.45 -6.24 -0.32 1.31e-9 Longevity; LIHC cis rs4555082 0.957 rs2816628 chr14:105736134 T/G cg13114125 chr14:105738426 BRF1 -0.7 -9.74 -0.47 6.04e-20 Mean platelet volume;Platelet distribution width; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24769499 chr2:120189242 TMEM37 -0.58 -6.89 -0.35 2.74e-11 Systolic blood pressure; LIHC cis rs644799 0.930 rs631099 chr11:95563482 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg20295408 chr7:1910781 MAD1L1 -0.56 -8.41 -0.41 1.15e-15 Bipolar disorder and schizophrenia; LIHC cis rs28374715 0.681 rs28712264 chr15:41588797 T/C cg18705301 chr15:41695430 NDUFAF1 -1.23 -17.07 -0.68 1.13e-47 Ulcerative colitis; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs1451375 0.617 rs1376524 chr7:50563582 G/A cg14593290 chr7:50529359 DDC -0.61 -10.0 -0.48 7.91e-21 Malaria; LIHC cis rs34375054 0.624 rs12580033 chr12:125676083 A/T cg25124228 chr12:125621409 AACS -0.42 -6.94 -0.35 2.03e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs2274273 1.000 rs7493394 chr14:55617755 A/T cg01864836 chr14:55583639 NA -0.36 -6.12 -0.31 2.62e-9 Protein biomarker; LIHC cis rs372883 0.648 rs1153292 chr21:30689195 G/T cg08807101 chr21:30365312 RNF160 -0.5 -5.79 -0.3 1.63e-8 Pancreatic cancer; LIHC cis rs611744 0.967 rs627604 chr8:109189819 C/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs2153535 0.580 rs7767756 chr6:8453428 A/C cg21535247 chr6:8435926 SLC35B3 0.63 8.46 0.42 8.11e-16 Motion sickness; LIHC cis rs5770917 1.000 rs762677 chr22:51017713 G/A cg19112186 chr22:51016638 CPT1B;CHKB-CPT1B -0.39 -5.74 -0.3 2.06e-8 Narcolepsy; LIHC cis rs3736594 1.000 rs3736594 chr2:27995781 A/C cg27432699 chr2:27873401 GPN1 -0.4 -6.24 -0.32 1.31e-9 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs9649213 0.593 rs736753 chr7:97931489 G/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.82e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs72781680 1.000 rs72796359 chr2:24160545 T/C cg08917208 chr2:24149416 ATAD2B 0.96 8.33 0.41 1.97e-15 Lymphocyte counts; LIHC cis rs8014671 0.597 rs1044527 chr14:70833819 C/G cg25576086 chr14:70833871 SYNJ2BP -0.56 -10.54 -0.5 1.15e-22 Prostate cancer; LIHC cis rs9902453 1.000 rs6505152 chr17:28331466 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC trans rs10411161 0.808 rs892040 chr19:52396645 A/G cg22319618 chr22:45562946 NUP50 -0.65 -7.43 -0.37 9.01e-13 Breast cancer; LIHC cis rs2404602 0.692 rs12437733 chr15:77155562 A/G cg23625390 chr15:77176239 SCAPER 0.35 5.73 0.3 2.19e-8 Blood metabolite levels; LIHC cis rs950776 0.518 rs28438420 chr15:78836288 A/T cg06917634 chr15:78832804 PSMA4 -0.63 -9.99 -0.48 8.83e-21 Sudden cardiac arrest; LIHC cis rs4466137 0.953 rs1420654 chr5:82975793 G/A cg16102102 chr5:83017553 HAPLN1 -0.58 -8.8 -0.43 6.86e-17 Prostate cancer; LIHC cis rs2839186 0.605 rs2839170 chr21:47671305 A/G cg13126279 chr21:47581558 C21orf56 -0.37 -5.84 -0.3 1.18e-8 Testicular germ cell tumor; LIHC cis rs3106136 0.527 rs2632411 chr4:95149434 G/A cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.02 -0.44 1.33e-17 Capecitabine sensitivity; LIHC cis rs9534288 0.797 rs4337200 chr13:46531749 G/A cg15192986 chr13:46630673 CPB2 -0.55 -8.44 -0.42 9.24e-16 Blood protein levels; LIHC cis rs250677 0.687 rs36044 chr5:148441128 T/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.48 -0.38 6.18e-13 Breast cancer; LIHC cis rs2573652 1.000 rs11634977 chr15:100516472 G/A cg09918751 chr15:100517450 ADAMTS17 -0.84 -15.91 -0.65 4.87e-43 Height; LIHC cis rs9309473 1.000 rs3738848 chr2:73761881 G/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.95 -0.35 1.87e-11 Metabolite levels; LIHC cis rs4853012 0.887 rs77148265 chr2:74339519 C/T cg20891558 chr2:74357851 NA 0.81 16.24 0.66 2.37e-44 Gestational age at birth (maternal effect); LIHC cis rs17685 0.712 rs1637049 chr7:75729975 C/G cg04610667 chr7:75704037 NA -0.33 -5.94 -0.31 7.17e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg02475777 chr4:1388615 CRIPAK -0.5 -7.46 -0.37 7.07e-13 Longevity; LIHC cis rs6960043 0.782 rs1558317 chr7:15065564 T/A cg19272540 chr7:15055459 NA -0.24 -6.63 -0.34 1.34e-10 Type 2 diabetes; LIHC cis rs13108904 0.905 rs34490749 chr4:1217981 A/G cg05665937 chr4:1216051 CTBP1 0.49 7.23 0.36 3.19e-12 Obesity-related traits; LIHC cis rs3806843 1.000 rs10038174 chr5:140210616 G/A cg19875535 chr5:140030758 IK 0.36 5.76 0.3 1.88e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2073300 1.000 rs6132631 chr20:23461848 T/C cg12062639 chr20:23401060 NAPB 0.78 9.74 0.47 6.27e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2274273 0.837 rs7148171 chr14:55770744 G/C cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.37e-9 Protein biomarker; LIHC cis rs7937682 0.632 rs11214037 chr11:111773296 C/T cg09085632 chr11:111637200 PPP2R1B 0.93 13.78 0.6 1.2e-34 Primary sclerosing cholangitis; LIHC cis rs9918079 0.560 rs4557256 chr4:15626647 A/C cg21329975 chr4:15471214 CC2D2A -0.42 -6.29 -0.32 9.48e-10 Obesity-related traits; LIHC cis rs600806 0.665 rs1368988 chr1:110012123 A/T cg10127483 chr1:110009974 SYPL2 0.5 6.44 0.33 4.1e-10 Intelligence (multi-trait analysis); LIHC cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg27572855 chr1:25598939 RHD 0.43 9.55 0.46 2.65e-19 Erythrocyte sedimentation rate; LIHC cis rs2153535 0.601 rs9505473 chr6:8538777 T/C cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.58e-15 Motion sickness; LIHC cis rs4423214 0.879 rs1790353 chr11:71136730 C/T cg05163923 chr11:71159392 DHCR7 -0.64 -8.71 -0.43 1.3e-16 Vitamin D levels; LIHC trans rs1005277 0.602 rs1740743 chr10:38519222 C/T cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC trans rs1493916 0.748 rs34501189 chr18:31314196 A/G cg27147174 chr7:100797783 AP1S1 -0.47 -6.72 -0.34 7.49e-11 Life satisfaction; LIHC cis rs11785400 1.000 rs4736365 chr8:143742197 A/G cg10596483 chr8:143751796 JRK 0.51 8.32 0.41 2.06e-15 Schizophrenia; LIHC cis rs8017423 0.967 rs11621045 chr14:90714003 C/T cg04374321 chr14:90722782 PSMC1 0.73 14.29 0.61 1.18e-36 Mortality in heart failure; LIHC trans rs877282 0.945 rs877280 chr10:771599 C/T cg22713356 chr15:30763199 NA 1.42 12.94 0.57 1.88e-31 Uric acid levels; LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg06558623 chr16:89946397 TCF25 0.86 13.32 0.58 7.01e-33 Skin colour saturation; LIHC cis rs79419269 0.673 rs2792432 chr7:150927763 T/C cg01623806 chr7:150929509 CHPF2 -0.55 -5.77 -0.3 1.73e-8 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs66569888 0.754 rs6719028 chr2:106895212 T/C cg15412446 chr2:106886593 NA 0.74 7.34 0.37 1.53e-12 Facial morphology (factor 23); LIHC cis rs763121 0.853 rs138712 chr22:39141600 C/T cg06022373 chr22:39101656 GTPBP1 0.7 12.82 0.57 5.26e-31 Menopause (age at onset); LIHC cis rs10870270 1.000 rs6560694 chr10:133773448 G/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.77 -0.57 8.47e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7520050 0.966 rs809775 chr1:46538040 A/T cg03146154 chr1:46216737 IPP -0.36 -6.01 -0.31 4.78e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg16132339 chr22:24313637 DDTL;DDT 0.73 14.29 0.61 1.21e-36 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1371867 0.875 rs1788178 chr8:101332518 A/C cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC cis rs9611565 0.729 rs202654 chr22:41841034 G/A cg03806693 chr22:41940476 POLR3H 0.54 7.18 0.36 4.29e-12 Vitiligo; LIHC cis rs7546668 1.000 rs12124078 chr1:15869899 A/G cg11706911 chr1:15910989 AGMAT 0.43 6.48 0.33 3.11e-10 Glomerular filtration rate (creatinine); LIHC cis rs10489202 1.000 rs3767474 chr1:168062398 C/T cg24449463 chr1:168025552 DCAF6 -0.5 -6.35 -0.32 6.85e-10 Schizophrenia; LIHC cis rs7677751 1.000 rs73252946 chr4:55125992 G/A cg17187183 chr4:55093834 PDGFRA 0.66 7.73 0.39 1.19e-13 Corneal astigmatism; LIHC cis rs10911251 0.528 rs2333622 chr1:183075456 T/C ch.1.3577855R chr1:183094577 LAMC1 0.62 10.74 0.5 2.15e-23 Colorectal cancer; LIHC cis rs12594515 0.694 rs2068295 chr15:45985546 T/C cg19682013 chr15:45996608 NA 0.39 6.77 0.34 5.62e-11 Waist circumference;Weight; LIHC cis rs2455799 0.552 rs2470540 chr3:15718652 T/A cg12698662 chr3:15914712 MIR563 -0.36 -6.57 -0.33 1.87e-10 Mean platelet volume; LIHC trans rs6489882 0.703 rs10774673 chr12:113361158 C/T cg10175203 chr3:128143634 NA 0.4 6.49 0.33 3.02e-10 Chronic lymphocytic leukemia; LIHC cis rs7584330 0.868 rs2325839 chr2:238386286 T/C cg14458575 chr2:238380390 NA 0.45 7.0 0.35 1.4e-11 Prostate cancer; LIHC cis rs875971 0.638 rs801205 chr7:66022144 C/A cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC cis rs2976388 0.609 rs2585150 chr8:143792669 C/T cg06565975 chr8:143823917 SLURP1 0.33 6.38 0.33 5.92e-10 Urinary tract infection frequency; LIHC cis rs1198430 1.000 rs1198430 chr1:23755513 C/T cg13183780 chr1:23809682 ASAP3 0.48 7.33 0.37 1.62e-12 Total cholesterol levels; LIHC cis rs17685 0.753 rs10952840 chr7:75772878 C/T cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs875971 0.545 rs316305 chr7:65617971 G/A cg26939375 chr7:64535504 NA -0.41 -6.47 -0.33 3.36e-10 Aortic root size; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg00800038 chr16:89945340 TCF25 0.6 10.06 0.48 4.9e-21 Skin colour saturation; LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.966 rs10508816 chr10:35459976 G/A cg03585969 chr10:35415529 CREM 0.79 11.75 0.54 5.18e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12220238 1.000 rs115418388 chr10:75976296 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.62 6.12 0.31 2.54e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7312933 1.000 rs7957213 chr12:42475438 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.84 0.35 3.63e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs12500138 1.000 rs59157290 chr4:166214959 C/T cg25064052 chr4:166216151 KLHL2 -0.62 -5.86 -0.3 1.12e-8 Cognitive function; LIHC cis rs7208859 0.623 rs12103440 chr17:29086657 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 8.11e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10861342 0.892 rs3829297 chr12:105592823 G/C cg23923672 chr12:105501055 KIAA1033 0.62 7.36 0.37 1.34e-12 IgG glycosylation; LIHC cis rs1559088 0.948 rs12460195 chr19:33584479 G/A cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1570884 0.556 rs2146146 chr13:50170368 C/T cg03651054 chr13:50194643 NA 0.38 6.65 0.34 1.17e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs10493773 0.609 rs11161651 chr1:86177816 A/G cg17807903 chr1:86174739 ZNHIT6 -0.61 -11.93 -0.54 1.16e-27 Urate levels in overweight individuals; LIHC cis rs9916302 0.847 rs7218670 chr17:37500424 G/A cg03013999 chr17:37608204 MED1 -0.35 -5.93 -0.31 7.41e-9 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg05590025 chr7:65112418 INTS4L2 -0.62 -6.7 -0.34 8.76e-11 Diabetic kidney disease; LIHC cis rs10493773 0.609 rs3753789 chr1:86174814 T/C cg17807903 chr1:86174739 ZNHIT6 -0.63 -12.45 -0.56 1.37e-29 Urate levels in overweight individuals; LIHC cis rs526231 0.819 rs2569016 chr5:102603132 A/G cg05225461 chr5:102596755 C5orf30 0.38 5.89 0.3 9.25e-9 Primary biliary cholangitis; LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg07167872 chr1:205819463 PM20D1 0.61 8.78 0.43 8.21e-17 Menarche (age at onset); LIHC cis rs922107 0.738 rs12733491 chr1:90039033 C/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.53 -0.38 4.6e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs9790314 0.580 rs10936227 chr3:161043869 A/C cg03342759 chr3:160939853 NMD3 -0.42 -6.07 -0.31 3.44e-9 Morning vs. evening chronotype; LIHC cis rs7903847 0.667 rs3818787 chr10:99145179 T/C cg08345082 chr10:99160200 RRP12 -0.39 -6.65 -0.34 1.14e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10197940 0.810 rs4664045 chr2:152267072 T/G cg19508488 chr2:152266495 RIF1 0.71 11.55 0.53 2.83e-26 Lung cancer; LIHC trans rs208520 0.690 rs1318604 chr6:66825278 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -8.03 -0.4 1.57e-14 Exhaled nitric oxide output; LIHC cis rs77633900 0.772 rs157760 chr15:76800260 A/G cg21673338 chr15:77095150 SCAPER -0.53 -6.09 -0.31 3.11e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs10193935 0.901 rs10179237 chr2:42515501 C/T cg27598129 chr2:42591480 NA -0.67 -10.4 -0.49 3.32e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg16145915 chr7:1198662 ZFAND2A -0.33 -7.87 -0.39 4.88e-14 Longevity;Endometriosis; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.61 -8.68 -0.42 1.67e-16 Lymphocyte counts; LIHC cis rs748404 0.578 rs2278856 chr15:43631356 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.56 10.05 0.48 5.4e-21 Lung cancer; LIHC cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC cis rs769267 0.895 rs1858999 chr19:19497669 C/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.54 -8.12 -0.4 8.67e-15 Tonsillectomy; LIHC cis rs5769765 0.862 rs138897 chr22:50231067 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -8.82 -0.43 5.94e-17 Schizophrenia; LIHC cis rs8081395 0.804 rs2777884 chr17:57830426 G/A cg13753209 chr17:57696993 CLTC -0.48 -7.3 -0.37 2.08e-12 White blood cell count; LIHC cis rs11122272 0.735 rs2572263 chr1:231509408 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs2115536 0.640 rs934134 chr15:80168218 T/C cg11839771 chr15:80205821 ST20 -0.32 -6.92 -0.35 2.21e-11 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs3768617 0.966 rs10911253 chr1:183086190 T/C ch.1.3577855R chr1:183094577 LAMC1 0.47 7.56 0.38 3.77e-13 Fuchs's corneal dystrophy; LIHC cis rs1062177 0.756 rs2964591 chr5:151117397 A/G cg00977110 chr5:151150581 G3BP1 -0.56 -7.11 -0.36 6.89e-12 Preschool internalizing problems; LIHC cis rs9303401 0.659 rs1864754 chr17:56688789 G/T cg10487724 chr17:56770010 TEX14;RAD51C -0.95 -13.05 -0.58 7.5e-32 Cognitive test performance; LIHC cis rs9309711 0.643 rs10188449 chr2:3480366 T/C cg04359351 chr2:3481828 TTC15 0.28 5.92 0.3 7.84e-9 Neurofibrillary tangles; LIHC trans rs208520 0.754 rs851594 chr6:66876695 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.61 -0.42 2.75e-16 Exhaled nitric oxide output; LIHC cis rs7959452 0.901 rs1384 chr12:69747834 C/T cg14784868 chr12:69753453 YEATS4 0.74 12.49 0.56 9.32e-30 Blood protein levels; LIHC cis rs3806843 1.000 rs12055222 chr5:140165568 T/C cg19875535 chr5:140030758 IK 0.36 5.95 0.31 6.51e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs2797160 1.000 rs1954361 chr6:126001423 C/G cg05039488 chr6:79577232 IRAK1BP1 -0.45 -6.48 -0.33 3.22e-10 Endometrial cancer; LIHC cis rs7647973 0.626 rs62260720 chr3:49853796 T/A cg03060546 chr3:49711283 APEH -0.61 -6.99 -0.35 1.43e-11 Menarche (age at onset); LIHC cis rs2710642 0.544 rs10204410 chr2:62829979 G/T cg17519650 chr2:63277830 OTX1 0.43 6.8 0.35 4.61e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs713477 0.692 rs56280202 chr14:55911201 C/T cg13175173 chr14:55914753 NA -0.31 -6.71 -0.34 8.09e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs10504229 0.610 rs6993531 chr8:58147283 A/G cg21724239 chr8:58056113 NA 0.48 6.35 0.32 6.91e-10 Developmental language disorder (linguistic errors); LIHC cis rs1843834 0.838 rs6436506 chr2:225558242 T/C cg22509189 chr2:225307070 NA -0.51 -6.63 -0.34 1.29e-10 IgE levels in asthmatics (D.p. specific); LIHC cis rs35110281 0.807 rs1598206 chr21:45058776 A/G cg01579765 chr21:45077557 HSF2BP -0.32 -6.07 -0.31 3.36e-9 Mean corpuscular volume; LIHC cis rs7927771 1.000 rs4752797 chr11:47874364 C/T cg20135002 chr11:47629003 NA -0.52 -8.78 -0.43 8.22e-17 Subjective well-being; LIHC trans rs7618501 1.000 rs3749240 chr3:49750188 T/A cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs7534824 0.625 rs17525507 chr1:101430504 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.68 6.98 0.35 1.58e-11 Refractive astigmatism; LIHC trans rs7374732 0.692 rs6800955 chr3:23139179 C/T cg27575106 chr3:119396361 COX17 0.4 6.48 0.33 3.12e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI;Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs7249142 0.526 rs7256811 chr19:19283551 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.93 -0.35 2.11e-11 IgG glycosylation; LIHC cis rs10883723 0.810 rs7074343 chr10:104283165 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs523522 0.923 rs10774553 chr12:120954984 T/C cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC cis rs12586317 0.547 rs112510746 chr14:35491833 T/G cg16230307 chr14:35515116 FAM177A1 0.78 13.24 0.58 1.39e-32 Psoriasis; LIHC cis rs754466 0.651 rs11002322 chr10:79649653 G/T cg17075019 chr10:79541650 NA -0.74 -11.02 -0.51 2.34e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs12752401 0.764 rs72725348 chr1:103024349 G/A cg03332897 chr19:740442 PALM 0.55 6.73 0.34 7.27e-11 Resistance to antihypertensive treatment in hypertension; LIHC cis rs9649213 0.593 rs62478200 chr7:97980045 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 4.92e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg24663255 chr8:146228920 ZNF252;C8orf77 -0.42 -6.41 -0.33 4.81e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11048434 0.736 rs11048344 chr12:9122609 G/C cg04155231 chr12:9217510 LOC144571 0.31 5.97 0.31 5.89e-9 Sjögren's syndrome; LIHC cis rs10838687 0.736 rs2242261 chr11:47266808 T/G cg26139080 chr11:47293733 MADD -0.42 -5.89 -0.3 8.99e-9 Proinsulin levels; LIHC cis rs769267 0.930 rs4808964 chr19:19603692 A/C cg03709012 chr19:19516395 GATAD2A -1.01 -18.18 -0.7 3.85e-52 Tonsillectomy; LIHC cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg05368731 chr17:41323189 NBR1 0.71 12.11 0.55 2.51e-28 Menopause (age at onset); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24664570 chr2:159825143 TANC1 0.46 6.9 0.35 2.48e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 0.905 rs444210 chr6:167390242 A/G cg12798992 chr6:167411361 FGFR1OP 0.55 9.21 0.45 3.32e-18 Crohn's disease; LIHC cis rs929354 1.000 rs1182413 chr7:157058557 G/A cg17757837 chr7:157058334 UBE3C -0.84 -14.07 -0.61 8.63e-36 Body mass index; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg26338869 chr17:61819248 STRADA 0.6 8.8 0.43 6.68e-17 Prudent dietary pattern; LIHC cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.967 rs4819222 chr21:47707778 G/A cg12379764 chr21:47803548 PCNT -0.6 -8.77 -0.43 8.36e-17 Testicular germ cell tumor; LIHC trans rs72829446 0.530 rs4796422 chr17:7380004 T/C cg08566640 chr11:64091735 NA -0.69 -6.54 -0.33 2.2e-10 Androgen levels; LIHC cis rs7945718 0.806 rs7480572 chr11:12787048 T/C cg25843174 chr11:12811716 TEAD1 0.28 6.49 0.33 2.97e-10 Educational attainment (years of education); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg13145437 chr2:85582358 ELMOD3;RETSAT 0.43 6.15 0.32 2.12e-9 Alopecia areata; LIHC cis rs7772486 0.754 rs9386132 chr6:146140751 T/C cg05347473 chr6:146136440 FBXO30 0.4 6.46 0.33 3.52e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4713118 0.513 rs149942 chr6:28001610 T/C cg23485639 chr6:28045615 ZNF165 0.39 5.94 0.31 7.13e-9 Parkinson's disease; LIHC cis rs9788682 0.948 rs34664138 chr15:78831624 T/G cg06917634 chr15:78832804 PSMA4 -0.53 -7.58 -0.38 3.27e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs947211 0.846 rs708726 chr1:205762139 G/T cg14893161 chr1:205819251 PM20D1 -0.34 -5.86 -0.3 1.1e-8 Parkinson's disease; LIHC cis rs875971 1.000 rs7783613 chr7:65805261 C/T cg18876405 chr7:65276391 NA -0.36 -6.54 -0.33 2.2e-10 Aortic root size; LIHC cis rs2832191 0.511 rs7278227 chr21:30482707 C/T cg24692254 chr21:30365293 RNF160 -0.38 -5.82 -0.3 1.37e-8 Dental caries; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC cis rs12478296 1.000 rs4973685 chr2:243019089 A/C cg05760424 chr2:242988095 NA -0.51 -6.91 -0.35 2.4e-11 Obesity-related traits; LIHC cis rs739401 0.595 rs6578304 chr11:2998279 A/G cg25174290 chr11:3078921 CARS -0.57 -8.74 -0.43 1.08e-16 Longevity; LIHC cis rs12477438 0.765 rs2167930 chr2:99592551 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.87 -0.47 2.27e-20 Chronic sinus infection; LIHC trans rs17685 0.593 rs56265719 chr7:75796269 C/T cg19862616 chr7:65841803 NCRNA00174 0.8 14.8 0.62 1.19e-38 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9910055 0.529 rs2523161 chr17:42179405 C/T cg19774624 chr17:42201019 HDAC5 0.52 6.52 0.33 2.59e-10 Total body bone mineral density; LIHC cis rs9837602 0.529 rs1688774 chr3:99521108 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.97 0.35 1.59e-11 Breast cancer; LIHC cis rs10871290 1.000 rs10871290 chr16:74472696 C/T cg01733217 chr16:74700730 RFWD3 -0.39 -6.66 -0.34 1.1e-10 Breast cancer; LIHC cis rs6594499 0.872 rs13178997 chr5:110444249 G/T cg04022379 chr5:110408740 TSLP 0.5 8.31 0.41 2.26e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs933688 1.000 rs11948075 chr5:90680579 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.44 0.66 3.67e-45 Smoking behavior; LIHC cis rs6582630 0.555 rs4601853 chr12:38435569 G/A cg26384229 chr12:38710491 ALG10B 0.61 8.48 0.42 6.79e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs6500602 0.647 rs4785967 chr16:4523208 G/A cg08645402 chr16:4508243 NA 0.47 8.98 0.44 1.82e-17 Schizophrenia; LIHC cis rs45430 0.928 rs398206 chr21:42742036 C/A cg06102954 chr21:42741788 MX2 0.38 6.53 0.33 2.33e-10 Melanoma; LIHC cis rs763121 0.853 rs5757141 chr22:38957483 G/A cg21395723 chr22:39101663 GTPBP1 0.37 5.71 0.3 2.44e-8 Menopause (age at onset); LIHC cis rs6840360 0.550 rs7675818 chr4:152690777 C/G cg22705602 chr4:152727874 NA -0.4 -8.47 -0.42 7.54e-16 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs9393021 chr6:8466123 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs1801251 1.000 rs13004406 chr2:233584557 A/T cg08000102 chr2:233561755 GIGYF2 -0.74 -11.21 -0.52 4.87e-25 Coronary artery disease; LIHC cis rs8062405 1.000 rs4788102 chr16:28873398 G/A cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9918079 0.560 rs7438356 chr4:15624770 C/T cg21329975 chr4:15471214 CC2D2A -0.44 -6.78 -0.34 5.2e-11 Obesity-related traits; LIHC cis rs7520050 0.966 rs10890363 chr1:46356148 C/T cg03146154 chr1:46216737 IPP 0.38 6.19 0.32 1.75e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6960043 0.818 rs2191348 chr7:15064255 G/T cg19272540 chr7:15055459 NA -0.24 -6.53 -0.33 2.41e-10 Type 2 diabetes; LIHC cis rs546131 0.642 rs12293044 chr11:34851049 T/G cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.52 -0.33 2.53e-10 Lung disease severity in cystic fibrosis; LIHC cis rs9517320 0.534 rs4772088 chr13:99138270 T/G cg07423050 chr13:99094983 FARP1 -0.51 -9.01 -0.44 1.44e-17 Longevity; LIHC cis rs7614311 0.731 rs73130544 chr3:63868596 G/A cg22134162 chr3:63841271 THOC7 -0.56 -6.21 -0.32 1.57e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs2153535 0.580 rs6910742 chr6:8448328 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.21e-26 Motion sickness; LIHC cis rs422249 0.547 rs102275 chr11:61557803 T/C cg27386326 chr11:61587980 NA 0.66 13.87 0.6 5.18e-35 Trans fatty acid levels; LIHC cis rs243505 0.668 rs2072406 chr7:148483760 G/A cg09806900 chr7:148480153 CUL1 0.45 6.7 0.34 8.62e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.54e-26 Alzheimer's disease; LIHC cis rs2180341 1.000 rs3798853 chr6:127636823 C/T cg27446573 chr6:127587934 RNF146 -0.99 -14.61 -0.62 6.69e-38 Breast cancer; LIHC cis rs11718455 0.960 rs34241796 chr3:44000394 A/T cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs1538970 0.816 rs10789464 chr1:45959102 C/T cg05343316 chr1:45956843 TESK2 0.63 9.45 0.46 5.47e-19 Platelet count; LIHC cis rs919433 0.680 rs2565163 chr2:198354414 T/C cg10820045 chr2:198174542 NA 0.54 8.7 0.43 1.42e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs74233809 1.000 rs11191479 chr10:104723620 T/C cg03493300 chr10:104813866 CNNM2 0.45 5.99 0.31 5.43e-9 Birth weight; LIHC cis rs12701220 0.553 rs7782024 chr7:1157502 G/T cg04498913 chr7:1135747 C7orf50 0.44 7.0 0.35 1.34e-11 Bronchopulmonary dysplasia; LIHC cis rs11190604 0.806 rs76835764 chr10:102193612 C/T cg07080220 chr10:102295463 HIF1AN 0.47 6.93 0.35 2.08e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25087434 chr10:11797550 ECHDC3 -0.4 -6.34 -0.32 7.1e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17854409 0.803 rs1048109 chr20:61472120 G/A cg07645718 chr20:61493192 TCFL5 0.79 6.45 0.33 3.85e-10 Obesity-related traits; LIHC cis rs13064411 0.696 rs6769516 chr3:113219905 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs10791097 0.748 rs2282579 chr11:130735482 C/T cg14779329 chr11:130786720 SNX19 0.4 6.18 0.32 1.83e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg12463550 chr7:65579703 CRCP 0.68 7.3 0.37 2.02e-12 Diabetic kidney disease; LIHC cis rs7618501 0.570 rs7613875 chr3:49971514 C/A cg21467203 chr3:49911342 NA -0.43 -7.62 -0.38 2.44e-13 Intelligence (multi-trait analysis); LIHC trans rs7618501 0.602 rs2526743 chr3:50115245 G/A cg21659725 chr3:3221576 CRBN -0.68 -10.84 -0.51 9.9899999999999993e-24 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.541 rs9405386 chr6:8458067 C/G cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs9486715 0.867 rs9486444 chr6:96963619 A/G cg06623918 chr6:96969491 KIAA0776 0.86 15.08 0.63 9.44e-40 Headache; LIHC cis rs10752881 1.000 rs12133714 chr1:182988252 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.35 0.49 5.1e-22 Colorectal cancer; LIHC cis rs12478296 0.892 rs11897561 chr2:243014976 C/A cg18898632 chr2:242989856 NA -0.47 -6.44 -0.33 4e-10 Obesity-related traits; LIHC cis rs7582720 1.000 rs72936323 chr2:204050474 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs8180040 0.701 rs62248439 chr3:46996448 A/G cg16586182 chr3:47516702 SCAP 0.48 8.64 0.42 2.16e-16 Colorectal cancer; LIHC cis rs77633900 0.772 rs284905 chr15:76743345 C/T cg21673338 chr15:77095150 SCAPER -0.51 -5.95 -0.31 6.51e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs2242116 0.727 rs10865943 chr3:46969970 T/C cg16586182 chr3:47516702 SCAP -0.38 -6.52 -0.33 2.59e-10 Birth weight; LIHC cis rs7208859 0.573 rs11656278 chr17:29075188 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg18305652 chr10:134549665 INPP5A 0.51 8.09 0.4 1.03e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6840360 0.837 rs13137669 chr4:152710943 A/G cg22705602 chr4:152727874 NA -0.32 -6.74 -0.34 6.57e-11 Intelligence (multi-trait analysis); LIHC cis rs7666738 0.924 rs11097592 chr4:98927532 C/T cg05340658 chr4:99064831 C4orf37 0.66 11.21 0.52 4.79e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs7172677 0.768 rs72730583 chr15:75351630 T/C cg17294928 chr15:75287854 SCAMP5 0.47 6.56 0.33 2e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9640161 0.830 rs36069544 chr7:150061538 G/A cg17279839 chr7:150038598 RARRES2 0.4 7.9 0.39 3.97e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs1799949 0.965 rs8176198 chr17:41230537 A/T cg25072359 chr17:41440525 NA 0.4 6.67 0.34 1e-10 Menopause (age at onset); LIHC trans rs9914544 0.932 rs11870265 chr17:18820985 A/T cg04702396 chr17:15466718 FAM18B2 0.45 7.06 0.36 9.45e-12 Educational attainment (years of education); LIHC cis rs4969178 0.965 rs16971105 chr17:76393975 G/T cg20026190 chr17:76395443 PGS1 0.44 6.94 0.35 1.93e-11 HDL cholesterol levels; LIHC cis rs765787 0.530 rs2413776 chr15:45544170 A/G cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.75 -0.3 1.96e-8 Uric acid levels; LIHC cis rs748404 0.518 rs480108 chr15:43817406 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.38 6.28 0.32 1.02e-9 Lung cancer; LIHC cis rs6435862 0.500 rs6756902 chr2:215672827 C/T cg04530015 chr2:215796436 ABCA12 0.49 9.01 0.44 1.46e-17 Neuroblastoma (high-risk); LIHC cis rs1355223 0.583 rs2941043 chr11:34870994 A/G cg24088639 chr11:34937564 PDHX;APIP 0.4 5.99 0.31 5.23e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11958404 0.615 rs7717235 chr5:157447772 C/G cg05962755 chr5:157440814 NA 0.61 7.98 0.4 2.23e-14 IgG glycosylation; LIHC cis rs60871478 0.947 rs62432255 chr7:804219 G/A cg13844804 chr7:814759 HEATR2 0.44 5.95 0.31 6.72e-9 Cerebrospinal P-tau181p levels; LIHC cis rs2404602 0.684 rs1011083 chr15:77007527 C/T cg03037974 chr15:76606532 NA -0.59 -10.08 -0.48 4.4e-21 Blood metabolite levels; LIHC trans rs668210 0.894 rs1786171 chr11:65769809 G/C cg17712092 chr4:129076599 LARP1B 0.6 7.51 0.38 5.35e-13 Cerebrospinal fluid biomarker levels; LIHC cis rs8180040 1.000 rs11130127 chr3:47398793 C/G cg16586182 chr3:47516702 SCAP 0.58 10.66 0.5 4.27e-23 Colorectal cancer; LIHC cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3762637 1.000 rs7645862 chr3:122221139 C/T cg24169773 chr3:122142474 KPNA1 -0.45 -9.0 -0.44 1.59e-17 LDL cholesterol levels; LIHC cis rs4665809 0.838 rs6546749 chr2:26306288 T/C cg27170947 chr2:26402098 FAM59B -0.67 -8.26 -0.41 3.13e-15 Gut microbiome composition (summer); LIHC cis rs11758351 0.660 rs113205297 chr6:26210808 A/C cg03854865 chr6:26224070 HIST1H3E 0.56 6.35 0.32 6.74e-10 Gout;Renal underexcretion gout; LIHC cis rs1801251 1.000 rs283477 chr2:233649427 A/G cg08000102 chr2:233561755 GIGYF2 0.77 11.81 0.54 3.03e-27 Coronary artery disease; LIHC cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg20607798 chr8:58055168 NA 0.64 7.7 0.38 1.51e-13 Developmental language disorder (linguistic errors); LIHC cis rs9326248 1.000 rs4938344 chr11:117003749 G/A cg10130564 chr11:117069849 TAGLN 0.35 5.83 0.3 1.28e-8 Blood protein levels; LIHC cis rs1577917 0.798 rs7772384 chr6:86639680 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.21 -0.36 3.63e-12 Response to antipsychotic treatment; LIHC cis rs12477438 0.501 rs2516833 chr2:99777405 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs875971 0.862 rs2901152 chr7:65765004 G/A cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs929354 0.806 rs28446734 chr7:156996775 T/C cg05182265 chr7:156933206 UBE3C -0.32 -5.95 -0.31 6.64e-9 Body mass index; LIHC cis rs10791097 0.609 rs3751039 chr11:130773076 A/G cg14779329 chr11:130786720 SNX19 -0.45 -7.07 -0.36 8.84e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs507080 0.922 rs533646 chr11:118566746 C/G cg04173919 chr11:118528438 PHLDB1 0.36 6.62 0.34 1.43e-10 Serum metabolite levels; LIHC cis rs2153535 0.541 rs6908504 chr6:8456778 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2439831 0.717 rs2470132 chr15:43835481 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.54 7.26 0.37 2.71e-12 Lung cancer in ever smokers; LIHC cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.92 0.3 7.74e-9 Menopause (age at onset); LIHC cis rs1059312 1.000 rs7302634 chr12:129279931 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -14.0 -0.6 1.58e-35 Systemic lupus erythematosus; LIHC cis rs12477438 0.520 rs11890338 chr2:99767868 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.5 0.77 1.86e-69 Chronic sinus infection; LIHC cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 7.43 0.37 9.02e-13 Platelet count; LIHC trans rs7618501 0.966 rs13085679 chr3:49869631 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.8 14.11 0.61 5.76e-36 Intelligence (multi-trait analysis); LIHC cis rs7592578 0.771 rs10432434 chr2:191387079 T/G cg10560079 chr2:191398806 TMEM194B -0.84 -12.24 -0.55 8.31e-29 Diastolic blood pressure; LIHC cis rs6503863 1 rs6503863 chr17:56517034 G/A cg25039879 chr17:56429692 SUPT4H1 0.42 5.82 0.3 1.36e-8 Intelligence (multi-trait analysis); LIHC cis rs17685 0.753 rs1859791 chr7:75786043 T/C cg16684958 chr7:75615977 POR 0.52 8.66 0.42 1.84e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7412746 0.658 rs12410394 chr1:150860186 G/A cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.81e-16 Melanoma; LIHC cis rs921968 0.643 rs537520 chr2:219381852 A/G cg17980119 chr2:219472607 PLCD4 0.35 6.12 0.31 2.56e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs6952808 0.771 rs10950415 chr7:1914477 A/G cg14004847 chr7:1930337 MAD1L1 -0.53 -7.72 -0.39 1.3e-13 Bipolar disorder and schizophrenia; LIHC cis rs919433 0.783 rs2565158 chr2:198236103 T/A cg03934865 chr2:198174659 NA 0.54 8.27 0.41 2.96e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs2363709 1.000 rs2363713 chr3:67422600 G/A cg13681781 chr9:139102396 QSOX2 0.83 6.35 0.32 6.79e-10 IgE levels; LIHC cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg10360323 chr17:41437877 NA 0.4 5.93 0.31 7.22e-9 Menopause (age at onset); LIHC cis rs9818758 0.556 rs9880309 chr3:49304329 G/C cg07636037 chr3:49044803 WDR6 -0.81 -8.29 -0.41 2.55e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6815814 0.731 rs66735315 chr4:38774180 G/T cg06935464 chr4:38784597 TLR10 0.38 5.96 0.31 6.18e-9 Breast cancer; LIHC cis rs7729447 0.566 rs3828589 chr5:32713327 T/C cg16267343 chr5:32710456 NPR3 0.48 6.1 0.31 2.9e-9 Blood pressure; LIHC cis rs477895 0.652 rs72920332 chr11:63947071 G/T cg05555928 chr11:63887634 MACROD1 0.51 6.64 0.34 1.24e-10 Mean platelet volume; LIHC cis rs763014 0.966 rs12935215 chr16:670605 T/C cg07343612 chr16:622815 PIGQ -0.87 -15.07 -0.63 1.04e-39 Height; LIHC cis rs9814567 1.000 rs28409322 chr3:134252385 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10792665 0.502 rs11233367 chr11:82610041 T/A cg24227371 chr11:82718527 RAB30 -0.27 -6.2 -0.32 1.61e-9 Obesity-related traits; LIHC cis rs240764 0.817 rs11155606 chr6:101163915 T/C cg09795085 chr6:101329169 ASCC3 -0.53 -7.4 -0.37 1.03e-12 Neuroticism; LIHC cis rs9399135 0.967 rs4895434 chr6:135293365 G/A cg22676075 chr6:135203613 NA 0.38 6.14 0.31 2.33e-9 Red blood cell count; LIHC cis rs7937682 0.883 rs11213941 chr11:111434094 T/C cg09085632 chr11:111637200 PPP2R1B 0.9 10.79 0.5 1.52e-23 Primary sclerosing cholangitis; LIHC cis rs910316 0.870 rs7147712 chr14:75670707 C/G cg11812906 chr14:75593930 NEK9 -0.62 -11.42 -0.53 8.1e-26 Height; LIHC cis rs9640161 0.830 rs6722 chr7:150068933 T/C cg10018233 chr7:150070692 REPIN1 0.72 13.44 0.59 2.32e-33 Blood protein levels;Circulating chemerin levels; LIHC cis rs11122272 0.735 rs1076804 chr1:231498460 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.46 0.46 5.03e-19 Hemoglobin concentration; LIHC cis rs2243480 0.901 rs778730 chr7:65823325 T/A cg18252515 chr7:66147081 NA -1.28 -17.31 -0.68 1.18e-48 Diabetic kidney disease; LIHC cis rs6088580 0.609 rs945674 chr20:32964247 G/C cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs11031096 0.679 rs12292515 chr11:4206385 T/G cg18678763 chr11:4115507 RRM1 -0.4 -5.86 -0.3 1.08e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1707322 0.721 rs56255771 chr1:46224319 C/T cg06784218 chr1:46089804 CCDC17 0.39 7.26 0.37 2.59e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1790761 0.692 rs10444362 chr11:67333090 G/A cg21734168 chr11:67353974 GSTP1 -0.27 -6.76 -0.34 6.08e-11 Mean corpuscular volume; LIHC cis rs1005277 0.579 rs1740747 chr10:38520465 G/A cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC trans rs11165623 0.792 rs6593599 chr1:96911468 C/T cg10631902 chr5:14652156 NA -0.34 -8.67 -0.42 1.74e-16 Hip circumference;Waist circumference; LIHC cis rs7762018 0.660 rs78181018 chr6:170096652 A/C cg19338460 chr6:170058176 WDR27 -0.84 -9.02 -0.44 1.36e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs78545713 0.541 rs111465843 chr6:26222823 G/A cg16070018 chr6:26224392 HIST1H3E 0.8 7.54 0.38 4.2e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs4788570 0.584 rs979790 chr16:71665985 A/T cg06353428 chr16:71660113 MARVELD3 -1.28 -10.98 -0.51 3.07e-24 Intelligence (multi-trait analysis); LIHC cis rs826838 1.000 rs11514441 chr12:38775190 C/T cg13010199 chr12:38710504 ALG10B 0.65 7.72 0.39 1.28e-13 Heart rate; LIHC cis rs1707322 0.721 rs11211178 chr1:46227566 G/T cg03146154 chr1:46216737 IPP 0.57 9.62 0.46 1.47e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs921968 0.565 rs2272191 chr2:219609776 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.97e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs5758659 0.967 rs5758670 chr22:42636687 T/C cg19513890 chr22:42538836 CYP2D7P1 -0.39 -7.65 -0.38 2.02e-13 Cognitive function; LIHC cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg05564831 chr3:52568323 NT5DC2 0.38 6.04 0.31 3.94e-9 Bipolar disorder; LIHC cis rs11671005 0.735 rs11666303 chr19:58922502 T/G cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs2346177 0.542 rs6757564 chr2:46702619 G/C cg02822958 chr2:46747628 ATP6V1E2 0.5 7.71 0.38 1.41e-13 HDL cholesterol; LIHC cis rs950169 0.614 rs12911536 chr15:84673030 G/T cg17507749 chr15:85114479 UBE2QP1 0.67 6.22 0.32 1.41e-9 Schizophrenia; LIHC cis rs67478160 0.643 rs6575997 chr14:104228546 C/T cg08213375 chr14:104286397 PPP1R13B -0.63 -12.44 -0.56 1.47e-29 Schizophrenia; LIHC cis rs11792861 0.926 rs17628095 chr9:111889172 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.57 -8.16 -0.4 6.64e-15 Menarche (age at onset); LIHC cis rs7666738 0.962 rs17027204 chr4:98997049 G/A cg05340658 chr4:99064831 C4orf37 0.68 11.56 0.53 2.64e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg09033563 chr22:24373618 LOC391322 0.66 9.6 0.46 1.7e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs79387448 1.000 rs79387448 chr2:103215410 C/T cg09003973 chr2:102972529 NA 0.86 6.26 0.32 1.17e-9 Gut microbiota (bacterial taxa); LIHC cis rs4969178 0.600 rs2376583 chr17:76402105 A/T cg05887092 chr17:76393375 PGS1 0.36 7.07 0.36 8.65e-12 HDL cholesterol levels; LIHC cis rs6701037 1.000 rs34493921 chr1:175122759 A/G cg00321850 chr1:175162397 KIAA0040 -0.38 -5.89 -0.3 9.28e-9 Alcohol dependence; LIHC cis rs3762637 0.943 rs72960447 chr3:122235105 G/A cg24169773 chr3:122142474 KPNA1 -0.44 -8.84 -0.43 5.15e-17 LDL cholesterol levels; LIHC cis rs9486715 1.000 rs6899647 chr6:97065661 A/G cg06623918 chr6:96969491 KIAA0776 -0.82 -13.52 -0.59 1.11e-33 Headache; LIHC cis rs703842 0.560 rs11533604 chr12:58047713 G/A cg18357645 chr12:58087776 OS9 -0.48 -7.26 -0.37 2.57e-12 Multiple sclerosis; LIHC cis rs561341 0.941 rs4625780 chr17:30249214 A/C cg13647721 chr17:30228624 UTP6 0.69 6.82 0.35 4.21e-11 Hip circumference adjusted for BMI; LIHC cis rs3892630 0.824 rs34425841 chr19:33231619 C/T cg22980127 chr19:33182716 NUDT19 1.02 11.92 0.54 1.28e-27 Red blood cell traits; LIHC cis rs10540 1.000 rs61876342 chr11:496193 T/G cg03576123 chr11:487126 PTDSS2 -1.09 -8.16 -0.4 6.35e-15 Body mass index; LIHC cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg11890956 chr21:40555474 PSMG1 1.07 15.83 0.65 9.81e-43 Cognitive function; LIHC trans rs8099121 0.585 rs76565763 chr18:4986099 A/G cg15792134 chr6:169051418 SMOC2 0.36 6.13 0.31 2.41e-9 Schizophrenia; LIHC cis rs7072216 0.666 rs11598689 chr10:100156027 G/T cg26618903 chr10:100175079 PYROXD2 -0.38 -5.82 -0.3 1.33e-8 Metabolite levels; LIHC cis rs7772486 0.597 rs9285508 chr6:146262697 G/T cg13319975 chr6:146136371 FBXO30 0.53 7.66 0.38 1.88e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.614 rs12948536 chr17:56580413 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.86 11.36 0.52 1.39e-25 Cognitive test performance; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg21747090 chr2:27597821 SNX17 -0.42 -6.24 -0.32 1.32e-9 Total body bone mineral density; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18642567 chr14:21755798 RPGRIP1 0.36 6.65 0.34 1.19e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs875971 0.755 rs76288834 chr7:66069802 G/A cg11764359 chr7:65958608 NA -0.77 -13.39 -0.59 3.52e-33 Aortic root size; LIHC cis rs6545883 0.931 rs778768 chr2:61790289 C/G cg14146966 chr2:61757674 XPO1 0.46 8.02 0.4 1.67e-14 Tuberculosis; LIHC cis rs12824058 0.831 rs11060825 chr12:130807905 A/G cg26677194 chr12:130822605 PIWIL1 0.52 7.19 0.36 3.99e-12 Menopause (age at onset); LIHC cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg14829360 chr17:73884958 NA -0.48 -7.18 -0.36 4.41e-12 Psoriasis; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg18538332 chr22:24372958 LOC391322 -0.58 -8.53 -0.42 4.84e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs798554 0.757 rs1182188 chr7:2869985 T/C cg19717773 chr7:2847554 GNA12 -0.43 -6.47 -0.33 3.31e-10 Height; LIHC cis rs11955398 0.716 rs12515025 chr5:59999437 G/A cg02684056 chr5:59996105 DEPDC1B 0.4 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs9378688 0.654 rs13217030 chr6:2248675 C/T cg12303981 chr6:2244766 GMDS -0.43 -5.77 -0.3 1.79e-8 Caudate nucleus volume; LIHC cis rs7592578 0.664 rs10931461 chr2:191405280 T/A cg10560079 chr2:191398806 TMEM194B 0.86 12.54 0.56 6.38e-30 Diastolic blood pressure; LIHC cis rs10504229 0.610 rs7011877 chr8:58147181 C/T cg21724239 chr8:58056113 NA 0.48 6.35 0.32 6.91e-10 Developmental language disorder (linguistic errors); LIHC cis rs17428076 0.836 rs3770455 chr2:172667895 C/T cg13550731 chr2:172543902 DYNC1I2 0.37 6.06 0.31 3.54e-9 Myopia; LIHC cis rs1003719 0.680 rs2187577 chr21:38533341 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs7633857 0.512 rs2376477 chr3:160700699 G/T cg03342759 chr3:160939853 NMD3 -0.41 -5.8 -0.3 1.49e-8 Educational attainment (years of education); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06253862 chr6:160201362 SNORA20;TCP1 0.5 7.18 0.36 4.32e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs921968 0.643 rs678218 chr2:219379709 C/A cg18887096 chr2:219472410 PLCD4 0.38 6.54 0.33 2.21e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg11062466 chr8:58055876 NA 0.45 6.12 0.31 2.5e-9 Developmental language disorder (linguistic errors); LIHC cis rs8180040 1.000 rs1638676 chr3:47327651 A/G cg16586182 chr3:47516702 SCAP -0.55 -9.99 -0.48 8.46e-21 Colorectal cancer; LIHC cis rs10838687 0.736 rs2306353 chr11:47256708 C/T cg25783544 chr11:47291846 MADD 0.46 5.77 0.3 1.73e-8 Proinsulin levels; LIHC cis rs1371867 0.810 rs1618528 chr8:101259134 T/C cg06002616 chr8:101225028 SPAG1 0.34 5.78 0.3 1.69e-8 Atrioventricular conduction; LIHC cis rs10785877 0.717 rs7848602 chr9:137120763 T/C cg21243944 chr9:137118148 NA -0.44 -6.1 -0.31 2.87e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs10790268 1 rs10790268 chr11:118729391 A/G cg19308663 chr11:118741387 NA -0.46 -6.01 -0.31 4.8e-9 Rheumatoid arthritis; LIHC cis rs10426930 0.752 rs56249413 chr19:5036730 G/A cg18473234 chr19:5097819 KDM4B 0.58 6.56 0.33 2e-10 Monocyte percentage of white cells; LIHC cis rs17001868 0.568 rs9607702 chr22:40739177 A/G cg07138101 chr22:40742427 ADSL 0.54 6.4 0.33 5.03e-10 Mammographic density (dense area); LIHC cis rs943466 0.614 rs4713677 chr6:33731225 C/G cg25922239 chr6:33757077 LEMD2 -0.46 -7.67 -0.38 1.85e-13 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC trans rs1814175 0.645 rs4598671 chr11:50003191 C/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs858239 0.539 rs2178140 chr7:23191625 G/C cg23682824 chr7:23144976 KLHL7 0.45 6.78 0.34 5.44e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg05439608 chr7:156761192 NOM1 0.41 6.46 0.33 3.58e-10 Immature fraction of reticulocytes; LIHC cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg17971929 chr21:40555470 PSMG1 0.73 8.59 0.42 3.13e-16 Cognitive function; LIHC cis rs72781680 0.528 rs56258075 chr2:24104256 C/G cg08917208 chr2:24149416 ATAD2B 0.87 8.2 0.41 4.78e-15 Lymphocyte counts; LIHC cis rs875971 0.929 rs778682 chr7:65837934 A/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs7917772 0.546 rs10883743 chr10:104338389 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.17e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6061231 0.583 rs2427313 chr20:60970675 G/A cg24112000 chr20:60950667 NA -0.59 -8.73 -0.43 1.14e-16 Colorectal cancer; LIHC cis rs6785206 0.892 rs2712429 chr3:128336221 A/C cg16766828 chr3:128327626 NA -0.61 -6.85 -0.35 3.55e-11 Lymphocyte percentage of white cells; LIHC cis rs9303401 0.614 rs3803753 chr17:56540110 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.39 0.52 1.05e-25 Cognitive test performance; LIHC cis rs2637266 1.000 rs2579746 chr10:78327674 C/T cg18941641 chr10:78392320 NA 0.28 5.86 0.3 1.11e-8 Pulmonary function; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg11070056 chr1:107600091 PRMT6 0.61 10.44 0.49 2.54e-22 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4979906 1.000 rs4979786 chr10:79444965 T/C cg07817648 chr10:79422355 NA -0.3 -6.19 -0.32 1.71e-9 Mortality in heart failure; LIHC trans rs1432089 0.773 rs114562833 chr4:171784712 A/G cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs7927771 1.000 rs4752856 chr11:47648042 C/T cg18512352 chr11:47633146 NA -0.25 -5.84 -0.3 1.24e-8 Subjective well-being; LIHC cis rs6912958 1.000 rs6937823 chr6:88160386 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.42 -7.25 -0.36 2.81e-12 Monocyte percentage of white cells; LIHC cis rs2304069 0.545 rs4705404 chr5:149381952 A/C cg12661370 chr5:149340060 SLC26A2 0.57 8.58 0.42 3.41e-16 HIV-1 control; LIHC cis rs2637266 0.905 rs1907313 chr10:78338072 A/G cg18941641 chr10:78392320 NA 0.28 5.92 0.3 7.79e-9 Pulmonary function; LIHC cis rs921968 0.643 rs537520 chr2:219381852 A/G cg02985541 chr2:219472218 PLCD4 0.45 8.81 0.43 6.32e-17 Mean corpuscular hemoglobin concentration; LIHC cis rs7216064 0.953 rs4791048 chr17:65848994 G/A cg12091567 chr17:66097778 LOC651250 -0.67 -9.67 -0.46 1.05e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs61931739 0.534 rs1490113 chr12:34132394 A/G cg26384229 chr12:38710491 ALG10B 0.52 7.07 0.36 8.54e-12 Morning vs. evening chronotype; LIHC trans rs3942852 0.774 rs10838812 chr11:48186924 T/C cg03929089 chr4:120376271 NA -0.56 -7.6 -0.38 2.9e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs2180341 1.000 rs2057223 chr6:127637374 T/C cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs909341 0.537 rs12481497 chr20:62385541 G/A cg14758556 chr20:62440591 NA 0.42 6.7 0.34 8.54e-11 Atopic dermatitis; LIHC trans rs561341 0.882 rs28649357 chr17:30367190 A/G cg20587970 chr11:113659929 NA -1.07 -10.11 -0.48 3.28e-21 Hip circumference adjusted for BMI; LIHC trans rs116095464 0.614 rs4371799 chr5:268192 C/A cg00938859 chr5:1591904 SDHAP3 0.58 7.15 0.36 5.43e-12 Breast cancer; LIHC cis rs17401966 0.838 rs8019 chr1:10366487 T/G cg19773385 chr1:10388646 KIF1B -0.4 -7.15 -0.36 5.3e-12 Hepatocellular carcinoma; LIHC cis rs3741404 0.537 rs1123251 chr11:63917601 G/T cg05555928 chr11:63887634 MACROD1 0.44 6.37 0.33 5.99e-10 Platelet count; LIHC cis rs7246657 0.943 rs7255972 chr19:37933841 T/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs864537 0.646 rs2995091 chr1:167434277 T/C cg22356347 chr1:167427500 CD247 -0.36 -6.04 -0.31 3.97e-9 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC trans rs60752752 0.852 rs3014880 chr1:153344374 C/G cg14901121 chr8:98817630 LAPTM4B -0.45 -6.65 -0.34 1.18e-10 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs7772486 0.686 rs9403746 chr6:146103768 C/A cg13319975 chr6:146136371 FBXO30 0.36 5.78 0.3 1.7e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4654899 0.644 rs6669077 chr1:21290520 A/C cg08539965 chr1:21396338 EIF4G3 0.34 6.15 0.32 2.22e-9 Superior frontal gyrus grey matter volume; LIHC cis rs3096299 0.874 rs3102342 chr16:89451575 T/C cg02187348 chr16:89574699 SPG7 0.52 7.56 0.38 3.77e-13 Multiple myeloma (IgH translocation); LIHC cis rs916888 0.773 rs199439 chr17:44793503 A/G cg01570182 chr17:44337453 NA 1.02 10.26 0.48 1.08e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg09033563 chr22:24373618 LOC391322 -0.46 -6.51 -0.33 2.68e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2625529 0.701 rs12911154 chr15:72212653 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.8 -0.3 1.48e-8 Red blood cell count; LIHC cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs10751667 0.643 rs6597970 chr11:928669 C/A cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs11098499 0.863 rs1010739 chr4:120463471 C/T cg09307838 chr4:120376055 NA 0.8 12.26 0.55 6.83e-29 Corneal astigmatism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12830327 chr11:85339628 TMEM126B;DLG2 0.5 6.88 0.35 2.94e-11 Lung function (FEV1/FVC); LIHC cis rs3008870 0.755 rs2815374 chr1:67507387 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.65 10.81 0.5 1.23e-23 Lymphocyte percentage of white cells; LIHC cis rs10792665 0.610 rs5006165 chr11:82557662 C/A cg24227371 chr11:82718527 RAB30 -0.25 -5.81 -0.3 1.41e-8 Obesity-related traits; LIHC cis rs9534288 0.797 rs7338189 chr13:46571035 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08051602 chr17:1394674 MYO1C -0.53 -6.36 -0.33 6.53e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs765787 0.530 rs4775835 chr15:45537553 T/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05788437 chr3:197476880 FYTTD1;KIAA0226 0.65 8.74 0.43 1.09e-16 Lung function (FEV1/FVC); LIHC cis rs526821 0.595 rs629948 chr11:55356448 G/A cg04317927 chr11:55418816 OR4S2 0.47 8.98 0.44 1.86e-17 Pediatric bone mineral density (spine); LIHC cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.04e-11 Alzheimer's disease; LIHC cis rs3749237 0.595 rs11720264 chr3:49580347 C/T cg07636037 chr3:49044803 WDR6 0.56 8.41 0.41 1.1e-15 Resting heart rate; LIHC cis rs74417235 0.684 rs13179358 chr5:154059746 C/A cg25588787 chr5:154027256 NA 0.38 5.73 0.3 2.17e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs7607369 0.580 rs7594289 chr2:219652286 A/G cg02176678 chr2:219576539 TTLL4 -0.43 -5.83 -0.3 1.26e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs1055129 0.537 rs2467100 chr17:73949038 C/G cg19302996 chr17:73780495 UNK -0.47 -6.69 -0.34 9.23e-11 White matter hyperintensity burden; LIHC cis rs10832963 1.000 rs2084220 chr11:18656932 C/T cg20219074 chr11:18656078 SPTY2D1 0.83 13.74 0.6 1.67e-34 Breast cancer; LIHC cis rs4148883 0.513 rs1154402 chr4:100009596 C/G cg12011299 chr4:100065546 ADH4 0.33 6.46 0.33 3.69e-10 Alcohol dependence; LIHC cis rs7945705 0.783 rs11042125 chr11:8938049 A/T cg12365402 chr11:9010492 NRIP3 -0.32 -8.43 -0.41 9.61e-16 Hemoglobin concentration; LIHC cis rs10504229 0.817 rs55949560 chr8:58167603 T/C cg21724239 chr8:58056113 NA 0.42 5.71 0.3 2.39e-8 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.604 rs34904312 chr7:1135883 G/A cg18765753 chr7:1198926 ZFAND2A -0.42 -5.92 -0.3 7.85e-9 Bronchopulmonary dysplasia; LIHC cis rs6121246 0.909 rs6060929 chr20:30345914 C/T cg13852791 chr20:30311386 BCL2L1 0.95 9.7 0.46 8.02e-20 Mean corpuscular hemoglobin; LIHC cis rs4407350 0.649 rs5764897 chr22:44930087 A/G cg26276947 chr22:44892394 LDOC1L 0.34 5.86 0.3 1.08e-8 Intelligence (multi-trait analysis); LIHC cis rs936229 0.813 rs2168519 chr15:75080872 T/C cg14664628 chr15:75095509 CSK -1.01 -20.44 -0.74 3.16e-61 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs2839186 0.934 rs2839194 chr21:47699437 T/G cg05896524 chr21:47604654 C21orf56 0.44 6.64 0.34 1.25e-10 Testicular germ cell tumor; LIHC cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg03452623 chr4:187889614 NA -0.33 -8.32 -0.41 2.05e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs9733 0.503 rs7556451 chr1:150913142 A/G cg18016565 chr1:150552671 MCL1 0.5 9.51 0.46 3.62e-19 Tonsillectomy; LIHC cis rs12477438 0.765 rs6750876 chr2:99679673 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg02290350 chr8:58132656 NA 0.5 9.52 0.46 3.18e-19 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.680 rs4732373 chr7:139086535 T/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs4970988 0.527 rs12067556 chr1:150614535 G/A cg15448220 chr1:150897856 SETDB1 0.38 5.87 0.3 1.05e-8 Urate levels; LIHC cis rs8180040 0.764 rs13062022 chr3:47169375 G/A cg02527881 chr3:46936655 PTH1R -0.31 -6.14 -0.32 2.24e-9 Colorectal cancer; LIHC cis rs3762637 0.941 rs9810996 chr3:122074387 G/A cg24169773 chr3:122142474 KPNA1 -0.49 -9.52 -0.46 3.18e-19 LDL cholesterol levels; LIHC cis rs919433 0.783 rs2565158 chr2:198236103 T/A cg10820045 chr2:198174542 NA 0.56 8.87 0.43 3.99e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21933743 chr11:65367160 MAP3K11 0.41 6.87 0.35 2.99e-11 Pancreatic cancer; LIHC cis rs782590 0.729 rs706548 chr2:55850106 C/G cg03859395 chr2:55845619 SMEK2 0.91 15.47 0.64 2.62e-41 Metabolic syndrome; LIHC cis rs11583043 0.874 rs41312668 chr1:101443582 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 9.15 0.44 5.43e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7089973 0.604 rs8181444 chr10:116588981 C/T cg03647239 chr10:116582469 FAM160B1 0.44 6.46 0.33 3.66e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9549367 0.789 rs2287250 chr13:113889474 C/T cg00898013 chr13:113819073 PROZ 0.35 6.43 0.33 4.22e-10 Platelet distribution width; LIHC cis rs2952156 0.959 rs1495102 chr17:37832093 T/C cg00129232 chr17:37814104 STARD3 -0.52 -9.47 -0.46 4.75e-19 Asthma; LIHC cis rs908922 0.676 rs1856120 chr1:152512441 G/A cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC trans rs561341 0.831 rs11658469 chr17:30206426 T/C cg20587970 chr11:113659929 NA 0.72 8.17 0.4 6.16e-15 Hip circumference adjusted for BMI; LIHC cis rs7715806 0.500 rs17649362 chr5:75008958 C/T cg00601450 chr5:74908170 NA 0.58 7.08 0.36 8.42e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg21782813 chr7:2030301 MAD1L1 0.49 8.62 0.42 2.48e-16 Bipolar disorder and schizophrenia; LIHC cis rs295140 0.605 rs159321 chr2:201184713 C/T cg23649088 chr2:200775458 C2orf69 -0.43 -6.02 -0.31 4.49e-9 QT interval; LIHC cis rs919433 0.617 rs10931793 chr2:198577585 G/A cg03934865 chr2:198174659 NA -0.48 -6.97 -0.35 1.68e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg13012494 chr21:47604986 C21orf56 0.39 6.06 0.31 3.54e-9 Testicular germ cell tumor; LIHC cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg22105103 chr4:187893119 NA -0.32 -8.08 -0.4 1.15e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.773 rs60466370 chr8:58171248 A/C cg02290350 chr8:58132656 NA 0.41 8.7 0.43 1.43e-16 Developmental language disorder (linguistic errors); LIHC cis rs116095464 0.850 rs10055295 chr5:243749 G/A cg22857025 chr5:266934 NA -1.48 -18.17 -0.7 4.09e-52 Breast cancer; LIHC cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg18876405 chr7:65276391 NA 0.56 9.46 0.46 5.21e-19 Calcium levels; LIHC cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg09323728 chr8:95962352 TP53INP1 -0.27 -6.07 -0.31 3.43e-9 Type 2 diabetes; LIHC cis rs1000083 0.666 rs727316 chr5:96625157 A/C ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs17376456 0.569 rs1026279 chr5:93209581 C/A cg25358565 chr5:93447407 FAM172A -0.8 -7.71 -0.38 1.41e-13 Diabetic retinopathy; LIHC cis rs4713118 0.955 rs9468203 chr6:27688667 A/G cg20933634 chr6:27740509 NA 0.45 6.01 0.31 4.67e-9 Parkinson's disease; LIHC cis rs6952808 0.609 rs6950151 chr7:1953521 T/C cg02951883 chr7:2050386 MAD1L1 -0.5 -7.58 -0.38 3.36e-13 Bipolar disorder and schizophrenia; LIHC cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg16606324 chr3:10149918 C3orf24 0.51 5.86 0.3 1.08e-8 Alzheimer's disease; LIHC cis rs9486715 0.867 rs9373833 chr6:96904998 A/G cg18709589 chr6:96969512 KIAA0776 -0.34 -5.98 -0.31 5.5e-9 Headache; LIHC cis rs7208859 0.573 rs4055105 chr17:29102550 A/G cg14067834 chr17:29058358 SUZ12P 0.71 7.08 0.36 8.01e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15140822 chr8:33423979 RNF122 0.46 6.31 0.32 8.61e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs644799 1.000 rs487609 chr11:95588102 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 16.26 0.66 1.88e-44 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs9388451 0.874 rs1159974 chr6:126090277 C/T cg05039488 chr6:79577232 IRAK1BP1 0.53 8.42 0.41 1.03e-15 Brugada syndrome; LIHC cis rs1506636 1.000 rs600774 chr7:123397831 C/T cg03229431 chr7:123269106 ASB15 0.59 11.79 0.54 3.71e-27 Plateletcrit;Platelet count; LIHC cis rs908922 0.676 rs6587681 chr1:152512135 C/T cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC cis rs1000083 0.748 rs2113015 chr5:96619623 T/G ch.5.96698337R chr5:96672581 NA 0.96 7.3 0.37 2.09e-12 Cisplatin-induced ototoxicity; LIHC cis rs4742903 0.935 rs10739885 chr9:106912892 G/A cg14250997 chr9:106856677 SMC2 0.37 6.4 0.33 5.27e-10 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6815814 0.731 rs28532329 chr4:38771368 C/T cg06935464 chr4:38784597 TLR10 0.38 5.96 0.31 6.18e-9 Breast cancer; LIHC cis rs2380220 0.510 rs9387562 chr6:96057006 G/T cg15832292 chr6:96025679 MANEA 0.67 8.61 0.42 2.67e-16 Behavioural disinhibition (generation interaction); LIHC cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg13395646 chr4:1353034 KIAA1530 -0.66 -9.5 -0.46 3.75e-19 Obesity-related traits; LIHC cis rs894734 0.535 rs2366143 chr12:54323256 G/A cg25024717 chr12:54324583 NA -0.38 -7.79 -0.39 8.17e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs12291225 0.585 rs4517475 chr11:14386145 A/G cg05501817 chr11:14380813 RRAS2 -0.45 -6.3 -0.32 9.24e-10 Sense of smell; LIHC cis rs2839186 0.867 rs13050387 chr21:47701423 C/T cg09417038 chr21:47716443 C21orf57 -0.5 -7.36 -0.37 1.35e-12 Testicular germ cell tumor; LIHC cis rs6546886 0.536 rs828868 chr2:74324504 A/G cg19729930 chr2:74357872 NA 0.32 5.94 0.31 7.21e-9 Dialysis-related mortality; LIHC cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg20607798 chr8:58055168 NA 0.59 6.94 0.35 1.92e-11 Developmental language disorder (linguistic errors); LIHC cis rs8005677 1.000 rs8006409 chr14:23396511 A/G cg25600027 chr14:23388339 RBM23 -0.41 -5.88 -0.3 9.92e-9 Cognitive ability (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00329943 chr16:72127485 TXNL4B;DHX38 0.45 6.79 0.34 4.98e-11 Calcium levels; LIHC cis rs6062302 0.522 rs2297428 chr20:62221766 C/T cg16989086 chr20:62203971 PRIC285 0.57 8.12 0.4 8.31e-15 Glioblastoma; LIHC trans rs3780486 0.505 rs10813959 chr9:33166234 C/T cg20290983 chr6:43655470 MRPS18A -0.83 -15.0 -0.63 1.97e-39 IgG glycosylation; LIHC cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg25894440 chr7:65020034 NA -0.52 -6.07 -0.31 3.44e-9 Diabetic kidney disease; LIHC cis rs9733 0.596 rs2867300 chr1:150666990 C/G cg15448220 chr1:150897856 SETDB1 0.43 6.68 0.34 9.91e-11 Tonsillectomy; LIHC trans rs6952808 0.692 rs11765549 chr7:2027311 G/T cg04565464 chr8:145669602 NFKBIL2 0.39 6.41 0.33 4.92e-10 Bipolar disorder and schizophrenia; LIHC cis rs1434579 0.897 rs12977016 chr19:44942756 G/A cg15540054 chr19:45004280 ZNF180 0.57 7.8 0.39 7.39e-14 Tuberculosis; LIHC cis rs6815814 0.731 rs4504265 chr4:38773865 G/T cg06935464 chr4:38784597 TLR10 0.38 5.96 0.31 6.18e-9 Breast cancer; LIHC cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg21724239 chr8:58056113 NA 0.6 7.22 0.36 3.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.632 rs12052246 chr2:172895606 G/T cg13550731 chr2:172543902 DYNC1I2 0.58 10.19 0.48 1.79e-21 Schizophrenia; LIHC cis rs4409675 0.556 rs2064710 chr1:28231154 G/A cg23691781 chr1:28212827 C1orf38 0.3 7.34 0.37 1.54e-12 Corneal astigmatism; LIHC cis rs8060686 0.545 rs12598630 chr16:68258852 T/G cg09835421 chr16:68378352 PRMT7 -0.52 -5.98 -0.31 5.58e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs11088226 0.645 rs78172258 chr21:33936539 T/G cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.1e-34 Gastritis; LIHC cis rs4788570 0.578 rs9934789 chr16:71662467 A/G cg06353428 chr16:71660113 MARVELD3 1.4 13.97 0.6 2.15e-35 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11890956 chr21:40555474 PSMG1 -0.41 -6.33 -0.32 7.48e-10 Cognitive function; LIHC cis rs35883536 0.609 rs12747197 chr1:101036831 A/C cg14515779 chr1:101123966 NA 0.43 5.92 0.3 7.9e-9 Monocyte count; LIHC cis rs12908161 0.959 rs34028043 chr15:85231585 G/A cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.03 9.99 0.48 8.36e-21 Platelet count; LIHC cis rs908922 0.676 rs12132469 chr1:152491856 G/T cg20991723 chr1:152506922 NA 0.59 10.48 0.49 1.85e-22 Hair morphology; LIHC cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.4e-11 Diabetic kidney disease; LIHC trans rs12752401 0.764 rs72725348 chr1:103024349 G/A cg24921808 chr19:740313 PALM 0.56 6.74 0.34 6.71e-11 Resistance to antihypertensive treatment in hypertension; LIHC cis rs6942756 0.806 rs6467240 chr7:128984018 T/C cg02491457 chr7:128862824 NA -0.57 -8.5 -0.42 5.99e-16 White matter hyperintensity burden; LIHC cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg20607798 chr8:58055168 NA 0.49 6.19 0.32 1.74e-9 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.596 rs11204704 chr1:150671630 T/C cg17724175 chr1:150552817 MCL1 0.48 9.74 0.47 6.17e-20 Tonsillectomy; LIHC cis rs9682041 0.696 rs35177863 chr3:170090006 A/G cg11886554 chr3:170076028 SKIL 0.66 5.99 0.31 5.18e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs1538970 1.000 rs4660852 chr1:45848931 A/C cg24296786 chr1:45957014 TESK2 0.49 7.37 0.37 1.26e-12 Platelet count; LIHC cis rs1030268 0.859 rs11763958 chr7:133417163 A/G cg03336402 chr7:133662267 EXOC4 -0.45 -6.36 -0.33 6.63e-10 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.901 rs66987549 chr4:1272617 C/T cg16405210 chr4:1374714 KIAA1530 -0.52 -7.75 -0.39 1.06e-13 Obesity-related traits; LIHC cis rs6424115 1.000 rs2179395 chr1:24148365 T/C cg10978503 chr1:24200527 CNR2 0.38 9.1 0.44 7.34e-18 Immature fraction of reticulocytes; LIHC cis rs17685 0.753 rs7804598 chr7:75702578 C/T cg01364799 chr7:75623366 TMEM120A -0.48 -7.2 -0.36 3.79e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7131987 0.903 rs2216853 chr12:29413248 C/G cg21522988 chr12:29376872 FAR2 0.3 6.86 0.35 3.28e-11 QT interval; LIHC cis rs919433 0.963 rs4850430 chr2:198182796 A/T cg10820045 chr2:198174542 NA -0.57 -9.61 -0.46 1.67e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg09417038 chr21:47716443 C21orf57 -0.58 -8.99 -0.44 1.71e-17 Testicular germ cell tumor; LIHC cis rs1669338 0.588 rs4684375 chr3:3170966 T/C cg16797762 chr3:3221439 CRBN -0.98 -8.39 -0.41 1.27e-15 White matter integrity; LIHC cis rs7833790 0.660 rs7839178 chr8:82763479 A/G cg17211192 chr8:82754475 SNX16 0.58 10.55 0.5 9.88e-23 Diastolic blood pressure; LIHC cis rs763121 0.853 rs4821811 chr22:39075145 C/T cg14440974 chr22:39074834 NA -0.45 -7.21 -0.36 3.67e-12 Menopause (age at onset); LIHC cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg25894440 chr7:65020034 NA -0.53 -6.04 -0.31 4.05e-9 Diabetic kidney disease; LIHC cis rs55665837 0.701 rs1522633 chr11:14645238 A/T cg19336497 chr11:14380999 RRAS2 -0.36 -6.07 -0.31 3.37e-9 Vitamin D levels; LIHC cis rs875971 0.638 rs35986979 chr7:66088990 G/A cg00343986 chr7:65444356 GUSB -0.39 -5.81 -0.3 1.45e-8 Aortic root size; LIHC cis rs6785206 0.730 rs9861429 chr3:128425749 A/G cg16766828 chr3:128327626 NA -0.57 -6.4 -0.33 5.14e-10 Lymphocyte percentage of white cells; LIHC cis rs7619427 0.544 rs9821661 chr3:44031551 G/A cg24966902 chr3:44043705 NA 0.53 8.23 0.41 4.07e-15 Schizophrenia; LIHC cis rs4319547 0.728 rs61954974 chr12:123074169 T/C cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.95 -0.39 2.84e-14 Body mass index; LIHC cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.59 0.56 3.89e-30 Colorectal cancer; LIHC trans rs2243480 1.000 rs78803505 chr7:65382572 A/T cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs7845219 0.525 rs3019175 chr8:95949013 G/A cg16049864 chr8:95962084 TP53INP1 -0.42 -6.57 -0.33 1.87e-10 Type 2 diabetes; LIHC cis rs7945718 0.875 rs9888178 chr11:12782643 C/T cg25843174 chr11:12811716 TEAD1 0.34 7.85 0.39 5.54e-14 Educational attainment (years of education); LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.55 7.75 0.39 1.07e-13 Lymphocyte counts; LIHC cis rs922107 0.967 rs6428555 chr1:90010388 A/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.83 -0.39 6.16e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7615952 0.599 rs12485717 chr3:125707075 C/T cg05084668 chr3:125655381 ALG1L 0.41 6.7 0.34 8.8e-11 Blood pressure (smoking interaction); LIHC cis rs1801251 1.000 rs7587309 chr2:233705702 G/T cg08000102 chr2:233561755 GIGYF2 -0.76 -11.56 -0.53 2.52e-26 Coronary artery disease; LIHC cis rs6952808 0.760 rs11764960 chr7:1950532 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.25 -0.45 2.4e-18 Bipolar disorder and schizophrenia; LIHC cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg23758822 chr17:41437982 NA 0.94 17.57 0.69 1.01e-49 Menopause (age at onset); LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.5 7.11 0.36 7.02e-12 Height; LIHC cis rs6879260 1.000 rs1035411 chr5:179729519 A/G cg23221052 chr5:179740743 GFPT2 -0.44 -5.95 -0.31 6.77e-9 Height; LIHC cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg21724239 chr8:58056113 NA 0.49 6.42 0.33 4.65e-10 Developmental language disorder (linguistic errors); LIHC cis rs4268898 0.662 rs74470633 chr2:24438712 A/G cg06627628 chr2:24431161 ITSN2 -0.73 -9.69 -0.46 8.82e-20 Asthma; LIHC cis rs7249142 0.549 rs741706 chr19:19281672 C/T cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.35 -5.85 -0.3 1.14e-8 IgG glycosylation; LIHC cis rs7582720 1.000 rs114079739 chr2:203825106 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg22903471 chr2:27725779 GCKR -0.48 -8.39 -0.41 1.27e-15 Total body bone mineral density; LIHC cis rs11792861 0.962 rs3829084 chr9:111801724 C/G cg05043794 chr9:111880884 C9orf5 0.3 7.1 0.36 7.4e-12 Menarche (age at onset); LIHC cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg13395646 chr4:1353034 KIAA1530 -0.64 -9.2 -0.45 3.62e-18 Obesity-related traits; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16436489 chr17:80757606 TBCD 0.44 6.75 0.34 6.23e-11 Longevity; LIHC cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 11.67 0.53 1.02e-26 Alzheimer's disease; LIHC cis rs6809651 0.524 rs4686728 chr3:185795333 C/T cg00760338 chr3:185826511 ETV5 0.82 12.62 0.56 3.13e-30 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs1580019 0.961 rs11768506 chr7:32494788 A/C cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs1559088 0.947 rs12461297 chr19:33559245 A/G cg17764715 chr19:33622953 WDR88 0.41 5.75 0.3 2.03e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs1385374 0.858 rs34888374 chr12:129296536 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -5.95 -0.31 6.49e-9 Systemic lupus erythematosus; LIHC cis rs7487075 0.619 rs7485580 chr12:46830374 A/C cg23829395 chr12:46796953 NA 0.34 6.05 0.31 3.81e-9 Itch intensity from mosquito bite; LIHC trans rs561341 1.000 rs55736640 chr17:30333848 G/A cg20587970 chr11:113659929 NA -1.49 -12.54 -0.56 6.15e-30 Hip circumference adjusted for BMI; LIHC cis rs919433 0.653 rs700651 chr2:198631714 G/A cg03934865 chr2:198174659 NA 0.48 6.87 0.35 3.09e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11212260 0.655 rs11212245 chr11:107319942 G/A cg25435332 chr11:107328525 CWF19L2 0.82 8.41 0.41 1.13e-15 IgG glycosylation; LIHC cis rs7666738 0.830 rs6830124 chr4:99054872 C/T cg05340658 chr4:99064831 C4orf37 -0.71 -13.07 -0.58 6.26e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs6121246 0.954 rs6060978 chr20:30416893 G/A cg13852791 chr20:30311386 BCL2L1 0.83 8.87 0.43 4.22e-17 Mean corpuscular hemoglobin; LIHC cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.89 0.3 9.25e-9 Bipolar disorder; LIHC cis rs6121246 0.567 rs2811 chr20:30194248 A/G cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs7107174 1.000 rs11237480 chr11:78110385 C/A cg02023728 chr11:77925099 USP35 0.41 7.61 0.38 2.77e-13 Testicular germ cell tumor; LIHC trans rs11165623 0.792 rs9437609 chr1:96977961 A/C cg10631902 chr5:14652156 NA -0.32 -7.53 -0.38 4.7e-13 Hip circumference;Waist circumference; LIHC cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg07424592 chr7:64974309 NA -0.8 -9.26 -0.45 2.4e-18 Diabetic kidney disease; LIHC cis rs7945705 0.712 rs61876274 chr11:9019190 A/T cg21881798 chr11:8931708 C11orf17;ST5 0.41 6.66 0.34 1.1e-10 Hemoglobin concentration; LIHC trans rs9929218 0.817 rs3114402 chr16:68719607 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.74 -10.93 -0.51 4.85e-24 Colorectal cancer; LIHC cis rs875971 0.830 rs778715 chr7:65849209 C/T cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC trans rs3780486 0.846 rs10113903 chr9:33122645 C/G cg04842962 chr6:43655489 MRPS18A -1.04 -24.22 -0.79 3.42e-76 IgG glycosylation; LIHC cis rs4803468 0.967 rs2304243 chr19:41942708 C/G cg14132834 chr19:41945861 ATP5SL 0.43 6.24 0.32 1.32e-9 Height; LIHC cis rs10876993 0.890 rs774891 chr12:58068571 G/A cg18357645 chr12:58087776 OS9 0.52 8.46 0.42 7.96e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.61 5.89 0.3 9.14e-9 Platelet count; LIHC cis rs778371 0.522 rs10205801 chr2:233597196 G/A cg08000102 chr2:233561755 GIGYF2 0.76 12.26 0.55 7.08e-29 Schizophrenia; LIHC cis rs922107 0.967 rs12752582 chr1:90019713 G/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.77 -0.39 9.19e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs1003719 0.788 rs9974286 chr21:38456832 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.77 -11.65 -0.53 1.23e-26 Eye color traits; LIHC cis rs4665809 1.000 rs1560868 chr2:26281459 A/T cg27170947 chr2:26402098 FAM59B 0.64 8.14 0.4 7.45e-15 Gut microbiome composition (summer); LIHC cis rs7216064 1.000 rs4569324 chr17:65872750 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.77 0.69 1.69e-50 Gut microbiome composition (summer); LIHC cis rs7249142 0.562 rs11085253 chr19:19277517 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.38 -6.16 -0.32 2.06e-9 IgG glycosylation; LIHC cis rs7592578 0.766 rs62182885 chr2:191437024 A/G cg27211696 chr2:191398769 TMEM194B -0.63 -7.92 -0.39 3.31e-14 Diastolic blood pressure; LIHC cis rs1707322 0.752 rs28507722 chr1:46206540 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg05484376 chr2:27715224 FNDC4 0.38 6.44 0.33 4.06e-10 Menopause (age at onset); LIHC trans rs867371 0.929 rs7176075 chr15:82471339 C/G cg18393722 chr15:85113863 UBE2QP1 -0.41 -6.88 -0.35 2.83e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs1728785 1.000 rs1645938 chr16:68595197 G/A cg02972257 chr16:68554789 NA -0.55 -6.21 -0.32 1.55e-9 Ulcerative colitis; LIHC cis rs6089584 0.893 rs2281735 chr20:60582540 T/A cg13770153 chr20:60521292 NA -0.34 -6.72 -0.34 7.41e-11 Body mass index; LIHC cis rs6586163 0.872 rs7914490 chr10:90747447 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.54 -7.82 -0.39 6.64e-14 Chronic lymphocytic leukemia; LIHC cis rs2580764 0.540 rs2920893 chr2:55270629 C/T cg09592903 chr2:55203963 RTN4 0.71 13.4 0.59 3.48e-33 Mean platelet volume; LIHC cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC cis rs7224314 1.000 rs8070284 chr17:65387400 A/G cg01507342 chr17:65387096 PITPNC1 -0.46 -5.9 -0.3 8.64e-9 Diisocyanate-induced asthma; LIHC trans rs9914544 0.545 rs8066636 chr17:18761109 G/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.8e-10 Educational attainment (years of education); LIHC cis rs77637988 0.578 rs6718068 chr2:48604978 C/T cg15846641 chr2:48541264 FOXN2 0.57 7.69 0.38 1.6e-13 Joint mobility (Beighton score); LIHC cis rs1914816 0.793 rs4636879 chr15:76630303 T/C cg03037974 chr15:76606532 NA 0.5 5.78 0.3 1.66e-8 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs8062405 0.755 rs12447461 chr16:28582941 C/A cg16576597 chr16:28551801 NUPR1 0.45 7.09 0.36 7.55e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs2637266 1.000 rs6480824 chr10:78355705 G/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs8060686 0.641 rs2418737 chr16:68122726 T/C cg05110241 chr16:68378359 PRMT7 -0.58 -6.83 -0.35 3.97e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs6942756 0.531 rs4731569 chr7:128930828 C/T cg02491457 chr7:128862824 NA 0.46 7.23 0.36 3.09e-12 White matter hyperintensity burden; LIHC cis rs12477438 0.798 rs2084987 chr2:99587885 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.85 -10.96 -0.51 3.82e-24 Chronic sinus infection; LIHC cis rs9517302 0.615 rs7983522 chr13:99098055 C/T cg24044564 chr13:99115944 STK24 0.39 5.79 0.3 1.58e-8 Obesity-related traits; LIHC trans rs2739330 0.828 rs5760108 chr22:24252668 G/T cg06437703 chr8:37914619 EIF4EBP1 -0.48 -7.26 -0.37 2.64e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17401966 1.000 rs12734551 chr1:10391536 A/C cg19773385 chr1:10388646 KIF1B -0.47 -8.1 -0.4 9.87e-15 Hepatocellular carcinoma; LIHC cis rs146817970 1 rs146817970 chr5:81512947 TA/T cg15871215 chr5:81402204 ATG10 -0.6 -5.9 -0.3 8.6e-9 Breast cancer; LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg06873352 chr17:61820015 STRADA 0.72 12.51 0.56 8.03e-30 Prudent dietary pattern; LIHC cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg25364880 chr3:44379878 C3orf23 0.55 7.44 0.37 7.99e-13 Depressive symptoms; LIHC cis rs11168351 0.864 rs10875743 chr12:48498413 C/T cg21466736 chr12:48725269 NA 0.63 9.14 0.44 5.64e-18 Bipolar disorder and schizophrenia; LIHC cis rs6750047 0.546 rs10192788 chr2:38272672 C/T cg07380506 chr2:38303506 CYP1B1 0.61 7.89 0.39 4.19e-14 Cutaneous malignant melanoma;Melanoma; LIHC cis rs1355223 0.867 rs2281908 chr11:34683578 C/T cg11058730 chr11:34937778 PDHX;APIP -0.42 -5.83 -0.3 1.29e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs8017423 0.586 rs2896134 chr14:90831293 G/A cg14092571 chr14:90743983 NA 0.41 5.73 0.3 2.25e-8 Mortality in heart failure; LIHC cis rs7107174 1.000 rs11237462 chr11:78058812 C/A cg02023728 chr11:77925099 USP35 0.48 9.05 0.44 1.12e-17 Testicular germ cell tumor; LIHC cis rs1728785 1.000 rs3203684 chr16:68600440 C/T cg02972257 chr16:68554789 NA 0.55 6.27 0.32 1.07e-9 Ulcerative colitis; LIHC cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.63 10.43 0.49 2.67e-22 Glycated hemoglobin levels; LIHC cis rs7772486 0.692 rs2265915 chr6:146194332 A/T cg13319975 chr6:146136371 FBXO30 -0.38 -6.25 -0.32 1.23e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6582630 0.519 rs4002438 chr12:38484880 C/T cg13010199 chr12:38710504 ALG10B 0.46 6.14 0.31 2.35e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs904251 0.797 rs1757177 chr6:37486370 C/T cg25019722 chr6:37503610 NA -0.37 -6.33 -0.32 7.75e-10 Cognitive performance; LIHC cis rs9368481 0.678 rs62402024 chr6:26923976 T/C cg12292205 chr6:26970375 C6orf41 0.45 7.68 0.38 1.69e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs7707921 0.881 rs17243791 chr5:81322547 A/G cg15871215 chr5:81402204 ATG10 -0.64 -6.37 -0.33 5.99e-10 Breast cancer; LIHC cis rs10791097 0.694 rs2155752 chr11:130755998 C/T cg14779329 chr11:130786720 SNX19 0.42 6.34 0.32 7.1e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg20295408 chr7:1910781 MAD1L1 -0.46 -6.73 -0.34 7.34e-11 Bipolar disorder and schizophrenia; LIHC cis rs1577917 1.000 rs12664335 chr6:86597774 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.44 7.25 0.37 2.79e-12 Response to antipsychotic treatment; LIHC cis rs4908768 0.906 rs751790 chr1:8529141 C/T cg20416874 chr1:8611966 RERE -0.54 -7.38 -0.37 1.22e-12 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7772486 0.790 rs4896852 chr6:146284621 T/C cg13319975 chr6:146136371 FBXO30 0.4 6.32 0.32 8.03e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg23758822 chr17:41437982 NA 0.94 17.82 0.69 1.05e-50 Menopause (age at onset); LIHC cis rs68170813 0.559 rs6963917 chr7:106953427 T/G cg02696742 chr7:106810147 HBP1 -0.51 -5.88 -0.3 9.71e-9 Coronary artery disease; LIHC cis rs7618501 0.633 rs7621026 chr3:49975334 A/G cg21467203 chr3:49911342 NA -0.45 -8.11 -0.4 9.32e-15 Intelligence (multi-trait analysis); LIHC cis rs6762 0.748 rs28636471 chr11:840639 T/A cg07691484 chr11:842764 TSPAN4;POLR2L -0.76 -9.53 -0.46 2.92e-19 Mean platelet volume; LIHC cis rs10870270 1.000 rs9971066 chr10:133788233 G/A cg26149184 chr10:133730230 NA 0.49 7.82 0.39 6.7e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1023500 0.573 rs133382 chr22:42471774 C/T cg04733989 chr22:42467013 NAGA 0.66 9.69 0.46 9.09e-20 Schizophrenia; LIHC cis rs1707322 1.000 rs4660889 chr1:46297331 C/T cg03146154 chr1:46216737 IPP 0.47 7.76 0.39 9.96e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg21448741 chr8:58168803 NA 0.36 6.62 0.34 1.38e-10 Developmental language disorder (linguistic errors); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg02189925 chr1:205091232 RBBP5 -0.42 -6.27 -0.32 1.11e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7617773 0.817 rs3937 chr3:48312402 T/C cg11946769 chr3:48343235 NME6 0.87 11.23 0.52 3.88e-25 Coronary artery disease; LIHC cis rs3936840 0.565 rs8011721 chr14:102986388 C/G cg10241871 chr14:102965420 TECPR2 0.44 6.66 0.34 1.08e-10 Plateletcrit; LIHC cis rs8177253 0.898 rs8177258 chr3:133480387 C/A cg12373951 chr3:133503437 NA 0.69 12.44 0.56 1.41e-29 Iron status biomarkers; LIHC cis rs7528419 1.000 rs629301 chr1:109818306 G/T cg06804625 chr1:109812012 CELSR2 -0.38 -5.77 -0.3 1.81e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs3764618 1.000 rs16981031 chr19:49497453 A/C cg14640682 chr19:49496473 GYS1;RUVBL2 -0.71 -5.81 -0.3 1.41e-8 Follicule stimulating hormone; LIHC cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg05552183 chr6:42928497 GNMT 0.81 12.02 0.55 5.2e-28 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg14159672 chr1:205819179 PM20D1 0.73 10.28 0.49 8.78e-22 Menarche (age at onset); LIHC cis rs10876993 0.890 rs1689597 chr12:58051886 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.78 -0.34 5.41e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs12908161 1.000 rs17600551 chr15:85319258 A/G cg17507749 chr15:85114479 UBE2QP1 0.62 7.05 0.36 1.02e-11 Schizophrenia; LIHC cis rs11997175 0.646 rs6468195 chr8:33724817 A/G ch.8.33884649F chr8:33765107 NA 0.31 5.77 0.3 1.82e-8 Body mass index; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06357940 chr3:58416685 PDHB 0.33 6.09 0.31 3.02e-9 Longevity; LIHC cis rs67460515 0.563 rs1599388 chr3:160846866 A/G cg17135325 chr3:160939158 NMD3 0.55 7.84 0.39 5.79e-14 Parkinson's disease; LIHC cis rs1801251 1.000 rs7592717 chr2:233577038 G/A cg25237894 chr2:233734115 C2orf82 0.57 10.94 0.51 4.3e-24 Coronary artery disease; LIHC cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC cis rs1790761 0.607 rs656652 chr11:67343957 C/T cg21734168 chr11:67353974 GSTP1 -0.28 -6.78 -0.34 5.17e-11 Mean corpuscular volume; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg10593459 chr1:44447478 B4GALT2 0.46 7.0 0.35 1.39e-11 Longevity; LIHC cis rs7917772 0.582 rs10786691 chr10:104364652 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6024905 0.722 rs2275954 chr20:36962667 C/T cg07053727 chr20:36965646 BPI -0.49 -8.56 -0.42 3.85e-16 Bipolar disorder and schizophrenia; LIHC cis rs9814567 1.000 rs35718987 chr3:134272783 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs477692 1.000 rs477692 chr10:131426022 T/C cg05714579 chr10:131428358 MGMT 0.47 7.93 0.39 3.22e-14 Response to temozolomide; LIHC cis rs2274273 0.870 rs10144345 chr14:55847737 T/C cg04306507 chr14:55594613 LGALS3 0.32 5.98 0.31 5.52e-9 Protein biomarker; LIHC cis rs4555082 0.718 rs2816619 chr14:105732551 G/C cg13114125 chr14:105738426 BRF1 -0.79 -10.09 -0.48 4e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs265548 0.646 rs36689 chr19:17910639 A/G cg16744531 chr19:17905626 B3GNT3 0.59 8.98 0.44 1.81e-17 Tumor biomarkers; LIHC cis rs798554 0.723 rs798518 chr7:2777825 A/G cg19346786 chr7:2764209 NA -0.45 -6.91 -0.35 2.33e-11 Height; LIHC cis rs1215050 0.740 rs783963 chr4:98989070 A/G cg05340658 chr4:99064831 C4orf37 0.38 5.82 0.3 1.39e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg16405210 chr4:1374714 KIAA1530 -0.9 -14.47 -0.62 2.31e-37 Longevity; LIHC cis rs9393692 0.905 rs7746807 chr6:26293338 C/A cg00631329 chr6:26305371 NA -0.45 -7.59 -0.38 3e-13 Educational attainment; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg07133347 chr1:107600762 PRMT6 -0.42 -6.24 -0.32 1.26e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11628318 0.713 rs1998419 chr14:103050397 C/G cg23461800 chr14:103021989 NA -0.54 -7.51 -0.38 5.19e-13 Platelet count; LIHC cis rs68170813 0.559 rs79705824 chr7:106848325 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.84 -0.3 1.19e-8 Coronary artery disease; LIHC cis rs9914988 0.887 rs4795456 chr17:27072463 G/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.92 -0.35 2.25e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs4555082 0.874 rs760270 chr14:105737785 A/G cg13114125 chr14:105738426 BRF1 -0.74 -9.73 -0.47 6.71e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs4891159 0.570 rs690132 chr18:74117261 T/C cg24786174 chr18:74118243 ZNF516 0.85 17.39 0.68 5.72e-49 Longevity; LIHC cis rs644799 1.000 rs516551 chr11:95588626 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.89 16.59 0.67 8.93e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6449957 0.832 rs960383 chr5:67450986 A/G cg23036683 chr5:67512108 NA 0.43 6.14 0.31 2.34e-9 Cleft lip with or without cleft palate; LIHC cis rs34779708 0.966 rs12774834 chr10:35400070 A/T cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs67311347 1.000 rs1466236 chr3:40462162 C/T cg18306943 chr3:40428807 ENTPD3 0.34 5.92 0.3 7.9e-9 Renal cell carcinoma; LIHC cis rs950169 0.922 rs11630507 chr15:85095725 A/G cg12863693 chr15:85201151 NMB 0.44 6.26 0.32 1.13e-9 Schizophrenia; LIHC cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg02290350 chr8:58132656 NA 0.41 8.59 0.42 3.16e-16 Developmental language disorder (linguistic errors); LIHC cis rs7582180 0.614 rs2241809 chr2:101014363 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.48 0.42 6.75e-16 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21496518 chr3:15374154 SH3BP5 0.38 6.21 0.32 1.57e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2073300 0.609 rs6137950 chr20:23418722 T/A cg16736954 chr20:23401023 NAPB 0.71 8.21 0.41 4.5e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8084351 0.599 rs12967822 chr18:50676348 C/G cg24270629 chr18:50823537 DCC -0.45 -6.66 -0.34 1.1e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2066819 0.901 rs1274490 chr12:56649601 A/G cg26734620 chr12:56694298 CS -0.93 -9.37 -0.45 1.05e-18 Psoriasis vulgaris; LIHC cis rs2836950 0.545 rs2836952 chr21:40616651 G/C cg11890956 chr21:40555474 PSMG1 -0.44 -7.17 -0.36 4.57e-12 Menarche (age at onset); LIHC cis rs262150 0.503 rs11769917 chr7:158817498 C/T cg19418458 chr7:158789849 NA -0.41 -6.79 -0.34 4.88e-11 Facial morphology (factor 20); LIHC cis rs12142240 0.667 rs41293287 chr1:46808852 C/T cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs965469 1.000 rs6051790 chr20:3342994 C/T cg25506879 chr20:3388711 C20orf194 -0.55 -6.57 -0.33 1.89e-10 IFN-related cytopenia; LIHC cis rs1801251 0.963 rs7562712 chr2:233606580 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.37 0.52 1.28e-25 Coronary artery disease; LIHC cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.52 -0.56 7.01e-30 Alzheimer's disease; LIHC cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg07424592 chr7:64974309 NA 0.74 8.34 0.41 1.84e-15 Diabetic kidney disease; LIHC cis rs11098499 0.562 rs2389879 chr4:120557684 G/A cg09307838 chr4:120376055 NA -0.57 -8.69 -0.43 1.52e-16 Corneal astigmatism; LIHC cis rs1008375 0.931 rs6449310 chr4:17575530 T/C cg16339924 chr4:17578868 LAP3 0.44 5.94 0.31 6.83e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10791323 0.593 rs2156676 chr11:133715791 G/C cg06766960 chr11:133703094 NA -0.67 -11.27 -0.52 2.79e-25 Childhood ear infection; LIHC cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg16822855 chr3:40428330 ENTPD3 0.32 5.89 0.3 9.15e-9 Renal cell carcinoma; LIHC cis rs7917772 0.582 rs11191352 chr10:104372244 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.52 8.0 0.4 1.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -8.05 -0.4 1.43e-14 Type 2 diabetes; LIHC cis rs7474896 0.515 rs662928 chr10:38316216 G/T cg25427524 chr10:38739819 LOC399744 0.45 5.9 0.3 8.53e-9 Obesity (extreme); LIHC cis rs9583531 0.689 rs9588247 chr13:111375571 G/T cg24331049 chr13:111365604 ING1 -0.78 -12.92 -0.57 2.33e-31 Coronary artery disease; LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg21782813 chr7:2030301 MAD1L1 0.41 6.97 0.35 1.65e-11 Bipolar disorder and schizophrenia; LIHC cis rs17685 0.672 rs6465011 chr7:75811297 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.37 -6.04 -0.31 4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3746446 0.678 rs6120777 chr20:33560172 G/A cg24642439 chr20:33292090 TP53INP2 0.69 7.06 0.36 9.42e-12 Congenital left-sided heart lesions; LIHC cis rs1552244 0.572 rs73117481 chr3:10160132 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs807029 0.544 rs55646950 chr10:102760996 C/T cg25179470 chr10:102756915 LZTS2 0.44 6.16 0.32 2.03e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs7833986 0.501 rs2719227 chr8:57043794 A/G cg23139584 chr8:56987506 RPS20;SNORD54 -0.75 -8.52 -0.42 5.3e-16 Height; LIHC cis rs7208859 0.623 rs73269988 chr17:29118145 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs365132 1.000 rs353478 chr5:176370988 T/C cg16309518 chr5:176445507 NA -0.58 -11.56 -0.53 2.66e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs8141529 0.764 rs5762824 chr22:29222930 C/T cg02153584 chr22:29168773 CCDC117 0.58 9.27 0.45 2.11e-18 Lymphocyte counts; LIHC cis rs892961 0.932 rs747481 chr17:75412143 A/G cg01320579 chr17:75405842 SEPT9 0.53 7.56 0.38 3.74e-13 Airflow obstruction; LIHC cis rs7107174 0.892 rs11237463 chr11:78060464 A/G cg02023728 chr11:77925099 USP35 0.47 8.92 0.43 2.88e-17 Testicular germ cell tumor; LIHC cis rs7107174 1.000 rs2292573 chr11:78053139 A/G cg02023728 chr11:77925099 USP35 0.42 8.22 0.41 4.19e-15 Testicular germ cell tumor; LIHC cis rs75908454 1.000 rs78348261 chr6:169831423 C/T cg19338460 chr6:170058176 WDR27 -0.86 -7.77 -0.39 9.33e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs11864453 0.647 rs10492813 chr16:72122463 A/G cg01557791 chr16:72042693 DHODH 0.4 6.7 0.34 8.61e-11 Fibrinogen levels; LIHC cis rs17776563 0.887 rs12148467 chr15:89128870 G/A cg05013243 chr15:89149849 MIR1179 0.41 6.79 0.34 4.84e-11 Thyroid hormone levels; LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg16060761 chr17:80687452 NA -0.48 -7.26 -0.37 2.6e-12 Glycated hemoglobin levels; LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg10755058 chr3:40428713 ENTPD3 0.4 6.73 0.34 7.35e-11 Renal cell carcinoma; LIHC cis rs10078 0.559 rs2672725 chr5:434981 G/C cg24955955 chr5:415729 AHRR 0.58 10.93 0.51 4.92e-24 Fat distribution (HIV); LIHC trans rs10411161 0.721 rs1433082 chr19:52390726 A/C cg22319618 chr22:45562946 NUP50 0.56 7.84 0.39 5.66e-14 Breast cancer; LIHC cis rs709400 0.663 rs7145113 chr14:103945414 A/G cg26031613 chr14:104095156 KLC1 0.73 9.24 0.45 2.62e-18 Body mass index; LIHC cis rs1018836 0.699 rs13271657 chr8:91474599 C/G cg16814680 chr8:91681699 NA -0.41 -6.62 -0.34 1.43e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7666738 0.830 rs10014284 chr4:98681951 G/C cg05340658 chr4:99064831 C4orf37 0.63 11.07 0.51 1.56e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs17125944 0.505 rs74642116 chr14:53213507 A/G cg13660082 chr14:53194042 PSMC6 -0.44 -7.63 -0.38 2.3e-13 Alzheimer's disease (late onset); LIHC cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg07424592 chr7:64974309 NA 0.81 9.45 0.45 5.58e-19 Diabetic kidney disease; LIHC cis rs7078219 0.505 rs7077040 chr10:101281014 C/G cg06854084 chr10:101292507 NKX2-3 -0.33 -6.19 -0.32 1.77e-9 Dental caries; LIHC cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg13047869 chr3:10149882 C3orf24 0.49 6.0 0.31 4.96e-9 Alzheimer's disease; LIHC cis rs10464366 0.519 rs6974609 chr7:39219149 C/T cg15212455 chr7:39170539 POU6F2 0.42 7.46 0.37 7.09e-13 IgG glycosylation; LIHC cis rs798554 1.000 rs798548 chr7:2760935 A/G cg13628971 chr7:2884303 GNA12 0.52 7.72 0.39 1.32e-13 Height; LIHC cis rs75920871 0.588 rs1815788 chr11:116834971 T/C cg01368799 chr11:117014884 PAFAH1B2 -0.43 -5.76 -0.3 1.85e-8 Subjective well-being; LIHC cis rs77633900 0.772 rs2460161 chr15:76640430 C/T cg21673338 chr15:77095150 SCAPER -0.53 -5.89 -0.3 9.09e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.38e-12 Bipolar disorder; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg09704166 chr2:114031854 PAX8;LOC440839 -0.32 -5.72 -0.3 2.38e-8 Lymphocyte counts; LIHC cis rs8044995 0.563 rs56331745 chr16:68368770 G/T cg05110241 chr16:68378359 PRMT7 -0.92 -10.44 -0.49 2.49e-22 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09782746 chr12:132553998 EP400 0.41 6.09 0.31 3.11e-9 Pancreatic cancer; LIHC cis rs1005277 0.579 rs2021649 chr10:38392122 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs6912958 0.781 rs2284908 chr6:88194500 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.06 -0.36 9.46e-12 Monocyte percentage of white cells; LIHC cis rs7223966 1.000 rs78172786 chr17:61847114 A/C cg05941027 chr17:61774174 LIMD2 0.38 7.73 0.39 1.24e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs11711311 0.736 rs13320940 chr3:113400954 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.35 -6.3 -0.32 8.97e-10 IgG glycosylation; LIHC cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs2836950 0.501 rs2070865 chr21:40715519 C/T cg11890956 chr21:40555474 PSMG1 -0.44 -7.16 -0.36 4.97e-12 Menarche (age at onset); LIHC cis rs3818285 0.504 rs4917547 chr10:111652285 T/C cg00817464 chr10:111662876 XPNPEP1 -0.47 -7.35 -0.37 1.44e-12 Superior crus of antihelix expression; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22827060 chr13:30424359 UBL3 -0.44 -6.21 -0.32 1.54e-9 Pancreatic cancer; LIHC cis rs2404602 0.647 rs11852395 chr15:77087785 T/C cg03037974 chr15:76606532 NA -0.6 -10.01 -0.48 7.34e-21 Blood metabolite levels; LIHC cis rs6121246 0.529 rs6060174 chr20:30183538 G/A cg13852791 chr20:30311386 BCL2L1 0.75 6.75 0.34 6.3e-11 Mean corpuscular hemoglobin; LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg19635926 chr16:89946313 TCF25 0.51 7.1 0.36 7.25e-12 Skin colour saturation; LIHC cis rs1046896 0.594 rs8070403 chr17:80865404 A/G cg02711726 chr17:80685570 FN3KRP -0.43 -7.83 -0.39 6.24e-14 Glycated hemoglobin levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16797244 chr6:12013002 HIVEP1 0.4 6.21 0.32 1.51e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1355223 0.583 rs2915177 chr11:34880266 A/G cg11058730 chr11:34937778 PDHX;APIP 0.77 14.0 0.6 1.63e-35 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs3780486 0.505 rs10758194 chr9:33157419 G/T cg04842962 chr6:43655489 MRPS18A 0.8 15.1 0.63 8.15e-40 IgG glycosylation; LIHC cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg13607699 chr17:42295918 UBTF -0.68 -13.32 -0.58 6.69e-33 Total body bone mineral density; LIHC cis rs1997103 0.871 rs1997101 chr7:55399652 A/T cg17469321 chr7:55412551 NA 0.48 7.1 0.36 7.37e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7739232 0.920 rs77374381 chr6:53530662 A/G cg00536792 chr6:53530503 KLHL31 -0.96 -6.93 -0.35 2.11e-11 Hip circumference adjusted for BMI; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.15.91235825F chr15:93434821 NA -0.34 -6.22 -0.32 1.44e-9 Cognitive function; LIHC cis rs2073499 1.000 rs2071803 chr3:50407344 G/T cg08207895 chr3:50388901 TUSC4;CYB561D2 0.59 6.32 0.32 8.24e-10 Schizophrenia; LIHC cis rs2932538 0.885 rs6691025 chr1:113177070 G/T cg22162597 chr1:113214053 CAPZA1 -0.73 -11.18 -0.52 6.11e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs7618501 0.602 rs2526743 chr3:50115245 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.14 -0.44 5.47e-18 Intelligence (multi-trait analysis); LIHC cis rs981946 0.544 rs12204759 chr6:3352636 G/A cg18842474 chr6:3356384 SLC22A23 0.36 5.73 0.3 2.23e-8 Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN); LIHC cis rs6545883 0.965 rs778752 chr2:61776902 C/G cg15711740 chr2:61764176 XPO1 -0.42 -5.96 -0.31 6.22e-9 Tuberculosis; LIHC cis rs311392 0.867 rs367108 chr8:55093142 G/A cg20636351 chr8:55087400 NA -0.38 -7.73 -0.39 1.2e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs4700695 0.764 rs251593 chr5:65313889 G/A cg21114390 chr5:65439923 SFRS12 0.45 5.8 0.3 1.48e-8 Facial morphology (factor 19); LIHC cis rs6831352 0.918 rs17218560 chr4:100060794 C/T cg12011299 chr4:100065546 ADH4 0.52 9.02 0.44 1.36e-17 Alcohol dependence; LIHC cis rs2354432 0.607 rs12402309 chr1:146721983 T/A cg25205988 chr1:146714368 CHD1L -0.9 -10.9 -0.51 5.93e-24 Mitochondrial DNA levels; LIHC cis rs9399135 0.967 rs11754783 chr6:135347661 T/A cg24558204 chr6:135376177 HBS1L 0.42 6.82 0.35 4.14e-11 Red blood cell count; LIHC cis rs4969178 0.560 rs4969182 chr17:76393030 T/C cg05887092 chr17:76393375 PGS1 0.36 6.95 0.35 1.85e-11 HDL cholesterol levels; LIHC cis rs5769765 0.862 rs7410537 chr22:50317330 G/A cg26441486 chr22:50317300 CRELD2 0.37 6.35 0.32 7.05e-10 Schizophrenia; LIHC cis rs3862030 0.810 rs11593710 chr10:104328719 A/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.51 -7.86 -0.39 5.01e-14 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg08219700 chr8:58056026 NA 0.46 5.78 0.3 1.64e-8 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13487185 chr1:29213677 EPB41 -0.44 -6.08 -0.31 3.2e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7044106 0.762 rs10984972 chr9:123409864 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.72 0.39 1.32e-13 Hip circumference adjusted for BMI; LIHC cis rs4319547 1.000 rs1392236 chr12:123074890 C/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.94 -0.39 2.85e-14 Body mass index; LIHC cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg16145915 chr7:1198662 ZFAND2A -0.33 -7.78 -0.39 8.49e-14 Longevity;Endometriosis; LIHC cis rs10791097 0.694 rs7940027 chr11:130745591 A/G cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs1493916 0.748 rs1389535 chr18:31310416 A/G cg27147174 chr7:100797783 AP1S1 0.45 6.44 0.33 4.01e-10 Life satisfaction; LIHC cis rs4908768 0.906 rs7539382 chr1:8579301 C/T cg20416874 chr1:8611966 RERE 0.56 8.65 0.42 1.99e-16 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs908922 0.651 rs7529157 chr1:152531365 C/A cg20991723 chr1:152506922 NA 0.53 8.76 0.43 9.49e-17 Hair morphology; LIHC cis rs6424115 1.000 rs1018396 chr1:24133612 G/A cg10978503 chr1:24200527 CNR2 0.36 8.55 0.42 4.08e-16 Immature fraction of reticulocytes; LIHC cis rs1506636 1.000 rs666266 chr7:123417759 A/G cg03229431 chr7:123269106 ASB15 0.6 11.85 0.54 2.27e-27 Plateletcrit;Platelet count; LIHC cis rs9902453 0.791 rs3115086 chr17:28025949 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.49 0.59 1.44e-33 Coffee consumption (cups per day); LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg06873352 chr17:61820015 STRADA 0.75 13.7 0.6 2.43e-34 Prudent dietary pattern; LIHC cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg23758822 chr17:41437982 NA 0.94 17.82 0.69 1.05e-50 Menopause (age at onset); LIHC cis rs950776 0.752 rs7182583 chr15:78899210 G/C cg06917634 chr15:78832804 PSMA4 0.61 8.38 0.41 1.39e-15 Sudden cardiac arrest; LIHC cis rs2075371 0.796 rs7780583 chr7:133960716 C/G cg11752832 chr7:134001865 SLC35B4 0.47 5.97 0.31 6.09e-9 Mean platelet volume; LIHC cis rs600806 0.888 rs638542 chr1:109845252 G/A cg08911820 chr1:110026001 ATXN7L2 -0.56 -6.59 -0.34 1.67e-10 Intelligence (multi-trait analysis); LIHC cis rs1008375 0.872 rs6831115 chr4:17640463 A/G cg02297831 chr4:17616191 MED28 0.51 7.96 0.4 2.49e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs5756813 0.688 rs34891095 chr22:38126582 C/T cg19894588 chr14:64061835 NA -0.61 -7.78 -0.39 8.85e-14 Optic cup area;Vertical cup-disc ratio; LIHC trans rs1945213 0.694 rs12422168 chr11:55866840 A/G cg03929089 chr4:120376271 NA 0.55 7.25 0.36 2.82e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg18252515 chr7:66147081 NA 1.29 17.34 0.68 9.06e-49 Diabetic kidney disease; LIHC cis rs2439831 0.867 rs6493082 chr15:43634808 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs8062405 1.000 rs62036620 chr16:28833097 A/G cg16576597 chr16:28551801 NUPR1 0.37 6.1 0.31 2.86e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs35150201 0.529 rs7806221 chr7:135318779 T/C cg23117316 chr7:135346802 PL-5283 -0.36 -6.43 -0.33 4.32e-10 Plateletcrit;Mean corpuscular hemoglobin;Mean platelet volume; LIHC cis rs10504229 0.679 rs16921606 chr8:58034477 A/C cg02290350 chr8:58132656 NA 0.29 6.84 0.35 3.75e-11 Developmental language disorder (linguistic errors); LIHC cis rs7106204 0.514 rs2083753 chr11:24255896 A/G ch.11.24196551F chr11:24239977 NA 0.83 12.03 0.55 5.01e-28 Response to Homoharringtonine (cytotoxicity); LIHC cis rs11018874 0.597 rs4393275 chr11:89886397 C/T cg23743573 chr11:89867420 NAALAD2 0.38 6.01 0.31 4.78e-9 White blood cell types; LIHC cis rs7412746 0.658 rs12067685 chr1:150952917 T/C cg17724175 chr1:150552817 MCL1 0.41 7.88 0.39 4.53e-14 Melanoma; LIHC cis rs4891159 0.790 rs8087557 chr18:74116848 G/C cg24786174 chr18:74118243 ZNF516 -0.79 -14.9 -0.63 4.73e-39 Longevity; LIHC cis rs11122272 0.701 rs743120 chr1:231531232 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs9581857 0.685 rs9319372 chr13:28042796 C/T cg22138327 chr13:27999177 GTF3A -0.8 -6.45 -0.33 3.93e-10 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC trans rs6467710 0.590 rs834441 chr7:137258446 T/C cg04467748 chr15:79760772 KIAA1024 0.42 7.1 0.36 7.42e-12 AIDS progression; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg06420487 chr17:61919686 SMARCD2 0.42 5.76 0.3 1.88e-8 Height; LIHC cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg08499158 chr17:42289980 UBTF 0.52 8.77 0.43 8.74e-17 Total body bone mineral density; LIHC cis rs589448 0.967 rs2617834 chr12:69753365 T/C cg19645103 chr12:69753606 YEATS4 -0.4 -5.92 -0.3 7.74e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg06873352 chr17:61820015 STRADA 0.74 13.22 0.58 1.66e-32 Prudent dietary pattern; LIHC cis rs7223966 1.000 rs9899491 chr17:61934384 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.54 6.59 0.34 1.71e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs847649 1.000 rs1100046 chr7:102549295 T/A cg18108683 chr7:102477205 FBXL13 -0.49 -7.43 -0.37 8.6e-13 Morning vs. evening chronotype; LIHC cis rs7072216 0.763 rs1061437 chr10:100176154 C/T cg26618903 chr10:100175079 PYROXD2 -0.38 -5.94 -0.31 7.1e-9 Metabolite levels; LIHC cis rs736408 0.812 rs9324 chr3:52825585 T/C cg10802521 chr3:52805072 NEK4 -0.37 -5.82 -0.3 1.36e-8 Bipolar disorder; LIHC cis rs11122272 0.735 rs1076804 chr1:231498460 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.83 -0.51 1.06e-23 Hemoglobin concentration; LIHC cis rs589448 0.902 rs2603089 chr12:69776800 C/T cg20891283 chr12:69753455 YEATS4 -0.94 -22.16 -0.77 4.43e-68 Cerebrospinal fluid biomarker levels; LIHC cis rs6450176 0.953 rs3776724 chr5:53292270 A/G ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.29 -0.64 1.35e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs10751667 1.000 rs10902246 chr11:953674 T/C cg06064525 chr11:970664 AP2A2 -0.5 -12.49 -0.56 9.37e-30 Alzheimer's disease (late onset); LIHC cis rs734999 0.505 rs10910107 chr1:2539181 C/T cg18854424 chr1:2615690 NA 0.33 7.38 0.37 1.23e-12 Ulcerative colitis; LIHC cis rs9914988 0.725 rs9905510 chr17:27092325 G/A cg20469991 chr17:27169893 C17orf63 -0.6 -7.04 -0.36 1.08e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC trans rs2727020 0.701 rs7949044 chr11:49597334 C/T cg18944383 chr4:111397179 ENPEP 0.32 7.57 0.38 3.55e-13 Coronary artery disease; LIHC trans rs916888 0.773 rs538628 chr17:44787313 G/C cg22968622 chr17:43663579 NA 1.17 12.88 0.57 3.18e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4332037 0.538 rs4721164 chr7:1932629 C/G cg23043544 chr7:2124092 MAD1L1 -0.38 -5.99 -0.31 5.21e-9 Bipolar disorder; LIHC cis rs17428076 0.874 rs12614709 chr2:172680872 C/G cg13550731 chr2:172543902 DYNC1I2 0.38 6.23 0.32 1.4e-9 Myopia; LIHC cis rs7224685 0.569 rs12942513 chr17:4016721 C/A cg11204139 chr17:3907470 NA 0.57 6.51 0.33 2.71e-10 Type 2 diabetes; LIHC cis rs66887589 0.560 rs9684327 chr4:120365441 A/G cg09307838 chr4:120376055 NA 0.48 7.25 0.37 2.74e-12 Diastolic blood pressure; LIHC cis rs11628318 0.853 rs6575925 chr14:103034507 C/T cg23461800 chr14:103021989 NA -0.47 -6.65 -0.34 1.15e-10 Platelet count; LIHC cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg02290350 chr8:58132656 NA 0.47 9.27 0.45 2.1e-18 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg11905131 chr22:24372483 LOC391322 -0.7 -10.73 -0.5 2.42e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1865760 1.000 rs56118523 chr6:25908975 A/G cg03517284 chr6:25882590 NA -0.38 -5.72 -0.3 2.27e-8 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05654049 chr3:23852499 UBE2E1 -0.47 -6.72 -0.34 7.59e-11 Cognitive function; LIHC cis rs67478160 0.608 rs11628787 chr14:104323984 G/A cg08213375 chr14:104286397 PPP1R13B -0.51 -9.36 -0.45 1.09e-18 Schizophrenia; LIHC cis rs9828933 1.000 rs9828933 chr3:64002897 T/C cg16258503 chr3:63850278 ATXN7;THOC7 -0.77 -9.64 -0.46 1.26e-19 Type 2 diabetes; LIHC cis rs1843834 0.539 rs12694643 chr2:225446603 A/G cg12698349 chr2:225449008 CUL3 0.67 10.4 0.49 3.48e-22 IgE levels in asthmatics (D.p. specific); LIHC cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.02 -0.44 1.42e-17 Bipolar disorder; LIHC cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg04944784 chr2:26401820 FAM59B -0.77 -9.44 -0.45 6.02e-19 Gut microbiome composition (summer); LIHC cis rs28374715 0.681 rs28728213 chr15:41653602 T/A cg18705301 chr15:41695430 NDUFAF1 -0.98 -14.14 -0.61 4.49e-36 Ulcerative colitis; LIHC trans rs8073060 0.544 rs225268 chr17:33966224 A/C cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs13113518 1.000 rs13132420 chr4:56392813 A/G cg15358633 chr12:38710606 ALG10B -0.42 -6.11 -0.31 2.73e-9 Height; LIHC cis rs6598955 0.724 rs12754536 chr1:26639605 T/C cg04990556 chr1:26633338 UBXN11 -0.61 -9.64 -0.46 1.34e-19 Obesity-related traits; LIHC cis rs4713118 0.868 rs7756968 chr6:27734954 C/G cg20933634 chr6:27740509 NA 0.49 6.26 0.32 1.18e-9 Parkinson's disease; LIHC cis rs963731 0.649 rs2888585 chr2:39246683 C/T cg04010122 chr2:39346883 SOS1 -0.7 -6.08 -0.31 3.14e-9 Corticobasal degeneration; LIHC cis rs34172651 0.876 rs11074653 chr16:24795959 C/T cg00339695 chr16:24857497 SLC5A11 0.53 7.99 0.4 2.04e-14 Intelligence (multi-trait analysis); LIHC cis rs471756 0.554 rs2484967 chr9:221874 C/T cg14500300 chr9:211689 NA 0.25 5.91 0.3 8.32e-9 Mean platelet volume; LIHC cis rs2625529 0.590 rs12442886 chr15:72473611 T/C cg16672083 chr15:72433130 SENP8 0.3 5.72 0.3 2.3e-8 Red blood cell count; LIHC trans rs7618501 0.932 rs4855850 chr3:49761571 G/A cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs6977660 0.941 rs5017197 chr7:19819967 T/A cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs738322 0.600 rs4821751 chr22:38564457 T/C cg25457927 chr22:38595422 NA -0.35 -8.62 -0.42 2.47e-16 Cutaneous nevi; LIHC trans rs2243480 1.000 rs7795242 chr7:65390094 T/C cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.52 0.49 1.28e-22 Total body bone mineral density; LIHC cis rs9303401 1.000 rs1390006 chr17:56890663 C/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.42 -6.32 -0.32 8.2e-10 Cognitive test performance; LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg11766577 chr21:47581405 C21orf56 -0.44 -7.09 -0.36 7.81e-12 Testicular germ cell tumor; LIHC cis rs875971 0.862 rs11984115 chr7:65773859 C/T cg18252515 chr7:66147081 NA 0.47 6.85 0.35 3.43e-11 Aortic root size; LIHC cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.42 0.45 6.79e-19 Platelet count; LIHC cis rs1371867 0.846 rs1660328 chr8:101303450 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -8.9 -0.43 3.31e-17 Atrioventricular conduction; LIHC cis rs6062302 0.522 rs13038448 chr20:62218453 C/T cg16989086 chr20:62203971 PRIC285 0.53 7.62 0.38 2.47e-13 Glioblastoma; LIHC cis rs1005277 0.540 rs1987431 chr10:37988887 T/C cg25427524 chr10:38739819 LOC399744 -0.63 -11.94 -0.54 1.07e-27 Extrinsic epigenetic age acceleration; LIHC cis rs2153535 0.601 rs2143352 chr6:8530248 G/C cg07606381 chr6:8435919 SLC35B3 0.79 11.5 0.53 4.42e-26 Motion sickness; LIHC cis rs17102423 0.731 rs998247 chr14:65546299 C/T cg16583315 chr14:65563665 MAX -0.4 -8.17 -0.4 6.11e-15 Obesity-related traits; LIHC cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg07414643 chr4:187882934 NA -0.22 -5.74 -0.3 2.09e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg06640241 chr16:89574553 SPG7 0.85 15.57 0.64 1.05e-41 Multiple myeloma (IgH translocation); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08541880 chr3:137833983 DZIP1L -0.44 -6.45 -0.33 3.89e-10 Pancreatic cancer; LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs10464366 0.544 rs4355688 chr7:39158402 C/T cg18850127 chr7:39170497 POU6F2 0.46 8.09 0.4 1.04e-14 IgG glycosylation; LIHC cis rs1008898 0.793 rs10257835 chr7:7234587 A/C cg19603390 chr7:7222222 C1GALT1 -0.47 -6.36 -0.33 6.62e-10 Coronary artery disease; LIHC cis rs10771431 0.597 rs3759275 chr12:9353828 A/T cg08997352 chr12:9597637 DDX12 -0.49 -7.61 -0.38 2.62e-13 Breast size; LIHC cis rs10751667 0.643 rs7479473 chr11:929111 C/T ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC cis rs9527 0.662 rs4919687 chr10:104595248 G/A cg15744005 chr10:104629667 AS3MT -0.34 -6.26 -0.32 1.13e-9 Arsenic metabolism; LIHC cis rs763121 0.853 rs5757208 chr22:39049230 A/C cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs3782089 1.000 rs3782089 chr11:65336819 C/T cg21890820 chr11:65308645 LTBP3 0.82 5.83 0.3 1.31e-8 Height; LIHC trans rs11039798 0.512 rs1588069 chr11:48694871 A/G cg15704280 chr7:45808275 SEPT13 0.61 6.99 0.35 1.44e-11 Axial length; LIHC cis rs2361718 0.590 rs4527052 chr17:78140910 A/G cg09238746 chr17:78121135 EIF4A3 -0.64 -10.51 -0.49 1.45e-22 Yeast infection; LIHC trans rs6952808 0.723 rs11766575 chr7:2005747 T/C cg04565464 chr8:145669602 NFKBIL2 0.42 7.0 0.35 1.33e-11 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg20607798 chr8:58055168 NA 0.69 7.73 0.39 1.25e-13 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.897 rs35784065 chr10:35353574 C/T cg03585969 chr10:35415529 CREM 0.86 12.99 0.57 1.26e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17253792 0.822 rs77420254 chr14:56069646 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs7216064 1.000 rs4790908 chr17:65852907 T/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.71 -0.46 7.52e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs250677 0.687 rs250672 chr5:148446110 A/G cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC cis rs35306767 0.715 rs11253550 chr10:1028288 C/G cg26597838 chr10:835615 NA 0.91 8.21 0.41 4.74e-15 Eosinophil percentage of granulocytes; LIHC cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.09 0.44 8.21e-18 Platelet count; LIHC trans rs9929218 1.000 rs13334471 chr16:68800452 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.78 -0.43 8.25e-17 Colorectal cancer; LIHC cis rs11098499 0.863 rs1480940 chr4:120457682 T/C cg09307838 chr4:120376055 NA 0.77 11.69 0.53 8.4e-27 Corneal astigmatism; LIHC cis rs4665809 1.000 rs4665306 chr2:26319124 C/T cg04944784 chr2:26401820 FAM59B -0.65 -8.29 -0.41 2.58e-15 Gut microbiome composition (summer); LIHC cis rs4660306 0.677 rs1006215 chr1:45909945 T/A cg03123370 chr1:45965343 CCDC163P;MMACHC 0.67 6.99 0.35 1.48e-11 Homocysteine levels; LIHC cis rs10751667 0.621 rs7394862 chr11:927500 T/C ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC cis rs1580019 0.844 rs4723159 chr7:32512804 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.98 16.61 0.67 7.54e-46 Cognitive ability; LIHC cis rs7116495 0.867 rs4378421 chr11:71761996 T/C cg26138937 chr11:71823887 C11orf51 -1.34 -10.79 -0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC cis rs9733 0.596 rs7418501 chr1:150711896 A/T cg13175981 chr1:150552382 MCL1 -0.43 -6.19 -0.32 1.72e-9 Tonsillectomy; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg10150615 chr22:24372951 LOC391322 0.43 6.3 0.32 8.92e-10 Morning vs. evening chronotype; LIHC cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg16606324 chr3:10149918 C3orf24 0.54 5.81 0.3 1.4e-8 Alzheimer's disease; LIHC cis rs3818285 1.000 rs3818285 chr10:111635212 T/C cg00817464 chr10:111662876 XPNPEP1 -0.41 -6.02 -0.31 4.44e-9 Superior crus of antihelix expression; LIHC cis rs9393692 0.905 rs9379838 chr6:26277133 C/T cg05868516 chr6:26286170 HIST1H4H 0.41 6.31 0.32 8.62e-10 Educational attainment; LIHC cis rs5769765 0.837 rs8142737 chr22:50291889 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.68 -8.89 -0.43 3.58e-17 Schizophrenia; LIHC cis rs903552 1.000 rs12915569 chr15:102001883 G/A cg06707286 chr15:102010195 PCSK6 -0.42 -5.97 -0.31 6.1e-9 Diabetic kidney disease; LIHC trans rs1005277 0.579 rs2474588 chr10:38420870 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.15 -0.52 8.04e-25 Extrinsic epigenetic age acceleration; LIHC cis rs3749237 0.576 rs4241406 chr3:49600426 C/T cg03060546 chr3:49711283 APEH 0.61 9.95 0.47 1.16e-20 Resting heart rate; LIHC cis rs4713118 0.662 rs9468275 chr6:28026136 G/T cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs4700695 0.841 rs27569 chr5:65373419 C/T cg21114390 chr5:65439923 SFRS12 -0.5 -6.83 -0.35 3.91e-11 Facial morphology (factor 19); LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg18110333 chr6:292329 DUSP22 -0.53 -6.9 -0.35 2.51e-11 Menopause (age at onset); LIHC cis rs765787 0.530 rs11854690 chr15:45516016 C/T cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC cis rs3096299 0.967 rs28575874 chr16:89469890 C/T cg00750074 chr16:89608354 SPG7 -0.38 -5.79 -0.3 1.59e-8 Multiple myeloma (IgH translocation); LIHC cis rs9486719 1.000 rs2472884 chr6:96863965 C/T cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs7666738 0.515 rs28615369 chr4:98896858 C/T cg05340658 chr4:99064831 C4orf37 0.52 6.91 0.35 2.34e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs2108622 0.727 rs77780918 chr19:15982707 T/C cg13772218 chr19:15982569 NA 0.37 7.78 0.39 8.7e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs6934970 1.000 rs12198343 chr6:113057679 T/C cg09308777 chr6:169852575 NA 0.58 6.06 0.31 3.67e-9 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg26338869 chr17:61819248 STRADA 0.6 8.77 0.43 8.84e-17 Prudent dietary pattern; LIHC cis rs2836950 0.545 rs4818001 chr21:40575088 T/C cg11890956 chr21:40555474 PSMG1 -0.48 -7.85 -0.39 5.32e-14 Menarche (age at onset); LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.63 0.62 5.37e-38 Prudent dietary pattern; LIHC cis rs4919087 0.590 rs78376466 chr10:99034835 G/A cg25902810 chr10:99078978 FRAT1 -0.61 -6.72 -0.34 7.57e-11 Monocyte count; LIHC cis rs6952808 0.691 rs2398709 chr7:2112548 C/T cg21782813 chr7:2030301 MAD1L1 0.39 6.78 0.34 5.34e-11 Bipolar disorder and schizophrenia; LIHC cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.63 0.38 2.39e-13 Bipolar disorder; LIHC cis rs11583043 1.000 rs2391573 chr1:101489698 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.59 7.94 0.39 2.93e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg00986762 chr1:36107072 PSMB2 0.4 6.25 0.32 1.2e-9 Metabolic traits; LIHC cis rs3749237 0.595 rs885592 chr3:49497883 T/G cg06212747 chr3:49208901 KLHDC8B 0.47 6.12 0.31 2.51e-9 Resting heart rate; LIHC trans rs2797160 1.000 rs2747722 chr6:126009629 A/G cg05039488 chr6:79577232 IRAK1BP1 0.46 6.5 0.33 2.88e-10 Endometrial cancer; LIHC cis rs1461503 0.966 rs10892939 chr11:122841959 T/C cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs4853012 0.838 rs72915068 chr2:74356185 G/A cg19729930 chr2:74357872 NA 0.86 19.94 0.73 3e-59 Gestational age at birth (maternal effect); LIHC cis rs2576037 0.526 rs1539878 chr18:44523004 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -6.96 -0.35 1.75e-11 Personality dimensions; LIHC cis rs600806 0.815 rs10858089 chr1:109926828 T/C cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.872 rs13046834 chr21:47701485 T/C cg12379764 chr21:47803548 PCNT -0.6 -8.77 -0.43 8.27e-17 Testicular germ cell tumor; LIHC cis rs7191439 0.858 rs11076701 chr16:88774525 A/G cg02389323 chr16:88786976 FAM38A 0.81 6.21 0.32 1.5e-9 Plateletcrit; LIHC cis rs9534288 0.783 rs1126366 chr13:46633148 C/G cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs735860 0.763 rs1429146 chr6:53130285 C/T cg10236188 chr6:53219634 NA -0.42 -7.73 -0.39 1.19e-13 Glaucoma; LIHC cis rs2180341 0.960 rs9401953 chr6:127687574 G/A cg27446573 chr6:127587934 RNF146 1.0 15.51 0.64 1.82e-41 Breast cancer; LIHC cis rs1707322 0.686 rs1541131 chr1:46084934 G/A cg24296786 chr1:45957014 TESK2 0.4 5.88 0.3 9.86e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1801251 1.000 rs283486 chr2:233644223 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.25 0.52 3.32e-25 Coronary artery disease; LIHC cis rs12474201 0.832 rs11695058 chr2:46978349 A/G cg06386533 chr2:46925753 SOCS5 0.54 6.07 0.31 3.34e-9 Height; LIHC cis rs8081395 0.741 rs180532 chr17:58003297 A/G cg13753209 chr17:57696993 CLTC 0.39 5.95 0.31 6.59e-9 White blood cell count; LIHC cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg20090690 chr10:134436459 INPP5A 0.42 5.72 0.3 2.27e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9596837 0.514 rs7320587 chr13:54201004 G/T ch.13.53330881F chr13:54432880 NA 0.36 6.46 0.33 3.61e-10 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25198656 chr7:5013641 RNF216L -0.37 -6.08 -0.31 3.18e-9 Pancreatic cancer; LIHC cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.63 0.34 1.27e-10 Bipolar disorder; LIHC cis rs12478296 0.901 rs59191623 chr2:243028595 G/A cg06360820 chr2:242988706 NA -0.8 -11.89 -0.54 1.58e-27 Obesity-related traits; LIHC cis rs10791097 0.667 rs2155358 chr11:130740357 T/C cg14779329 chr11:130786720 SNX19 0.4 6.03 0.31 4.25e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7078219 0.505 rs7916751 chr10:101285650 T/A cg17888390 chr10:101282816 NA -0.29 -5.71 -0.3 2.44e-8 Dental caries; LIHC cis rs6598955 0.543 rs112752634 chr1:26534217 G/A cg04990556 chr1:26633338 UBXN11 0.77 11.13 0.52 9.13e-25 Obesity-related traits; LIHC cis rs4927850 0.723 rs7630825 chr3:195753740 T/C cg00031303 chr3:195681400 NA 0.33 5.84 0.3 1.22e-8 Pancreatic cancer; LIHC cis rs826838 0.967 rs1684415 chr12:39130099 T/C cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs8062405 1.000 rs12446589 chr16:28870962 G/A cg07451762 chr16:28383216 NA 0.33 6.15 0.32 2.12e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9911578 0.967 rs2567892 chr17:56668929 T/C cg05425664 chr17:57184151 TRIM37 -0.58 -8.63 -0.42 2.41e-16 Intelligence (multi-trait analysis); LIHC cis rs17106184 1.000 rs2095864 chr1:51299597 A/G cg07174182 chr1:51127561 FAF1 0.58 6.43 0.33 4.18e-10 Type 2 diabetes; LIHC cis rs6754311 0.517 rs1469995 chr2:136542559 G/A cg07169764 chr2:136633963 MCM6 1.04 14.38 0.61 5.16e-37 Mosquito bite size; LIHC cis rs7937682 0.961 rs17113227 chr11:111620491 A/G cg09085632 chr11:111637200 PPP2R1B -1.21 -20.29 -0.74 1.16e-60 Primary sclerosing cholangitis; LIHC cis rs3857067 0.773 rs10023115 chr4:95095502 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.54 -0.38 4.19e-13 QT interval; LIHC cis rs12540874 0.670 rs3887826 chr7:50544961 G/A cg18232548 chr7:50535776 DDC -0.43 -6.45 -0.33 3.92e-10 Systemic sclerosis; LIHC cis rs10791097 0.694 rs1050071 chr11:130747231 C/G cg22079354 chr11:130786696 SNX19 0.43 5.92 0.3 7.82e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9640161 0.789 rs2098053 chr7:150043205 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.51 -8.31 -0.41 2.3e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs2304069 0.545 rs12153714 chr5:149395254 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.58 8.26 0.41 3.31e-15 HIV-1 control; LIHC cis rs6061231 1.000 rs67941642 chr20:60958108 C/T cg06026331 chr20:60912101 LAMA5 0.41 5.98 0.31 5.65e-9 Colorectal cancer; LIHC cis rs9916302 0.847 rs7218670 chr17:37500424 G/A cg07936489 chr17:37558343 FBXL20 0.83 13.53 0.59 1.02e-33 Glomerular filtration rate (creatinine); LIHC cis rs4671400 0.543 rs2290324 chr2:61448776 A/C cg14146966 chr2:61757674 XPO1 -0.37 -5.78 -0.3 1.66e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs6558530 0.640 rs7844748 chr8:1702343 C/T cg24391279 chr8:1708526 NA 0.37 6.56 0.33 1.94e-10 Systolic blood pressure; LIHC cis rs11971779 0.648 rs6946113 chr7:139106126 A/C cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs992157 1.000 rs13003334 chr2:219124921 T/A cg00012203 chr2:219082015 ARPC2 0.91 15.08 0.63 9.78e-40 Colorectal cancer; LIHC cis rs2304069 1.000 rs216126 chr5:149428424 G/C cg22760475 chr5:149380129 HMGXB3;TIGD6 0.86 10.58 0.5 8.35e-23 HIV-1 control; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03601098 chr7:127228532 ARF5 -0.48 -6.56 -0.33 2.02e-10 Systolic blood pressure; LIHC cis rs12479064 0.724 rs2305352 chr2:100015124 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -8.9 -0.43 3.35e-17 Chronic sinus infection; LIHC cis rs6545883 0.868 rs2427885 chr2:61816777 A/G cg14146966 chr2:61757674 XPO1 0.46 7.91 0.39 3.54e-14 Tuberculosis; LIHC cis rs56104184 0.830 rs17272658 chr19:49355405 C/T cg15549821 chr19:49342101 PLEKHA4 -1.17 -9.72 -0.47 7.12e-20 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs72772090 0.710 rs56122780 chr5:96059895 T/C cg17330273 chr5:96107758 CAST;ERAP1 -0.65 -7.2 -0.36 3.82e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs7618501 1.000 rs7649348 chr3:49772375 G/A cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 8.89 0.43 3.61e-17 Menarche (age at onset); LIHC cis rs35306767 0.903 rs35567307 chr10:915804 G/C cg26597838 chr10:835615 NA 1.18 14.34 0.61 7.88e-37 Eosinophil percentage of granulocytes; LIHC cis rs2235642 0.717 rs2236269 chr16:1652614 T/A cg03034668 chr16:1723424 CRAMP1L -0.38 -6.78 -0.34 5.27e-11 Coronary artery disease; LIHC cis rs7223966 0.655 rs6504165 chr17:61630076 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.53 5.79 0.3 1.57e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9902453 0.808 rs10445400 chr17:28183059 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 10.45 0.49 2.26e-22 Coffee consumption (cups per day); LIHC cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg06453172 chr10:134556979 INPP5A -0.65 -8.23 -0.41 4.09e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4654899 1.000 rs7535895 chr1:21439239 T/A cg08539965 chr1:21396338 EIF4G3 0.33 5.72 0.3 2.34e-8 Superior frontal gyrus grey matter volume; LIHC trans rs7618501 0.633 rs6446189 chr3:50008566 A/G cg21659725 chr3:3221576 CRBN 0.71 11.57 0.53 2.29e-26 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg02034447 chr16:89574710 SPG7 0.5 7.57 0.38 3.53e-13 Multiple myeloma (IgH translocation); LIHC cis rs2540917 0.765 rs243078 chr2:60615303 A/G cg00543073 chr2:60773386 BCL11A -0.32 -6.31 -0.32 8.48e-10 Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02983885 chr19:42772892 NA 0.48 6.64 0.34 1.26e-10 Pancreatic cancer; LIHC cis rs523522 0.962 rs7471 chr12:120941215 T/C cg27279351 chr12:120934652 DYNLL1 0.66 11.82 0.54 3e-27 High light scatter reticulocyte count; LIHC cis rs8141529 0.719 rs132561 chr22:29351179 C/T cg15103426 chr22:29168792 CCDC117 -0.56 -8.87 -0.43 4.19e-17 Lymphocyte counts; LIHC cis rs7635838 0.859 rs6779840 chr3:11425423 A/G cg00170343 chr3:11313890 ATG7 0.45 7.11 0.36 6.61e-12 HDL cholesterol; LIHC cis rs2857078 0.720 rs9906669 chr17:42305706 A/G cg08499158 chr17:42289980 UBTF -0.49 -7.94 -0.39 2.91e-14 Red cell distribution width;Reticulocyte count; LIHC cis rs8067354 0.872 rs2645483 chr17:57848184 T/G cg02344993 chr17:57696989 CLTC 0.53 8.46 0.42 7.98e-16 Hemoglobin concentration; LIHC cis rs2242420 0.920 rs12090311 chr1:21960194 G/T cg18150885 chr1:21978612 RAP1GAP -0.48 -5.86 -0.3 1.09e-8 Hematological and biochemical traits; LIHC cis rs8062405 1.000 rs62037364 chr16:28868695 G/A cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4713118 0.868 rs760587 chr6:27740300 C/A cg20933634 chr6:27740509 NA 0.48 6.26 0.32 1.15e-9 Parkinson's disease; LIHC cis rs644799 0.710 rs1852535 chr11:95501241 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.79 12.04 0.55 4.52e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24707616 chr17:16342815 NCRNA00188;SNORD49B;SNORD49A 0.46 6.47 0.33 3.31e-10 Pancreatic cancer; LIHC cis rs2243480 0.522 rs1638736 chr7:66092308 A/T cg12463550 chr7:65579703 CRCP 0.73 7.15 0.36 5.34e-12 Diabetic kidney disease; LIHC cis rs858239 0.600 rs2003555 chr7:23122915 C/T cg23682824 chr7:23144976 KLHL7 0.43 6.45 0.33 3.91e-10 Cerebrospinal fluid biomarker levels; LIHC trans rs3015497 0.603 rs3015455 chr14:51062162 G/A cg15834202 chr5:58865918 PDE4D 0.44 6.07 0.31 3.39e-9 Mean platelet volume; LIHC cis rs11229555 0.574 rs66573492 chr11:58183797 G/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4665809 1.000 rs11678157 chr2:26321526 T/C cg27170947 chr2:26402098 FAM59B -0.62 -7.91 -0.39 3.5e-14 Gut microbiome composition (summer); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01272081 chr9:32551527 TOPORS 0.46 6.62 0.34 1.41e-10 Cognitive function; LIHC cis rs1385374 0.858 rs3765107 chr12:129278310 A/G cg09035930 chr12:129282057 SLC15A4 -0.49 -5.86 -0.3 1.12e-8 Systemic lupus erythematosus; LIHC cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg02353165 chr6:42928485 GNMT 0.75 11.78 0.54 3.99e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6951245 0.935 rs11766669 chr7:1063593 C/T cg08132940 chr7:1081526 C7orf50 -0.76 -6.49 -0.33 3.02e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg09455208 chr3:40491958 NA 0.39 7.79 0.39 8.31e-14 Renal cell carcinoma; LIHC cis rs6840360 1.000 rs6535809 chr4:152592933 A/G cg22705602 chr4:152727874 NA -0.3 -6.46 -0.33 3.51e-10 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.06 0.55 3.63e-28 Prudent dietary pattern; LIHC cis rs8058578 1.000 rs3747481 chr16:30666367 C/T cg02466173 chr16:30829666 NA -0.46 -7.23 -0.36 3.1e-12 Multiple myeloma; LIHC cis rs17685 0.633 rs3801471 chr7:75696188 T/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.19 -0.32 1.68e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs77637988 0.578 rs11689645 chr2:48608559 G/C cg00032884 chr2:48540671 FOXN2 0.38 5.84 0.3 1.19e-8 Joint mobility (Beighton score); LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg18538332 chr22:24372958 LOC391322 -0.63 -9.15 -0.44 5.24e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs507080 0.883 rs693306 chr11:118558333 A/G cg04173919 chr11:118528438 PHLDB1 0.35 6.56 0.33 2.01e-10 Serum metabolite levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg16032384 chr1:17766173 RCC2 -0.39 -6.08 -0.31 3.13e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs4144743 1.000 rs61312893 chr17:45325023 C/G cg18085866 chr17:45331354 ITGB3 -0.57 -8.15 -0.4 6.83e-15 Body mass index; LIHC trans rs1814175 0.817 rs4881648 chr11:49812901 A/G cg03929089 chr4:120376271 NA -0.9 -18.4 -0.71 4.84e-53 Height; LIHC cis rs6938574 0.672 rs6569520 chr6:128365034 C/G cg11798873 chr6:128799726 PTPRK -0.47 -6.08 -0.31 3.18e-9 Menarche (age at onset); LIHC cis rs748404 0.660 rs493377 chr15:43773467 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.47 8.0 0.4 1.9e-14 Lung cancer; LIHC cis rs35110281 0.659 rs11702544 chr21:45091861 C/T cg21573476 chr21:45109991 RRP1B -0.59 -11.29 -0.52 2.46e-25 Mean corpuscular volume; LIHC cis rs459571 0.839 rs10993895 chr9:136887726 C/T cg13789015 chr9:136890014 NCRNA00094 -0.45 -8.45 -0.42 8.69e-16 Platelet distribution width; LIHC cis rs992157 0.717 rs3817266 chr2:219142594 C/T cg00012203 chr2:219082015 ARPC2 -0.82 -13.08 -0.58 5.58e-32 Colorectal cancer; LIHC cis rs10508774 1.000 rs72782237 chr10:32936671 A/G cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08805160 chr11:8704501 RPL27A;SNORA3 0.49 6.38 0.33 5.63e-10 Lung function (FEV1/FVC); LIHC cis rs2479724 0.935 rs2254936 chr6:41846569 A/G cg17623882 chr6:41773611 USP49 -0.56 -8.79 -0.43 7.45e-17 Menarche (age at onset); LIHC cis rs244293 0.931 rs244354 chr17:53194142 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.58 -0.38 3.2e-13 Menarche (age at onset); LIHC cis rs2412488 1.000 rs3765158 chr4:54327584 A/G cg22241045 chr4:54363911 LNX1 -0.45 -7.07 -0.36 8.51e-12 DNA methylation (variation); LIHC cis rs11229555 0.874 rs17567523 chr11:58354081 G/A cg15696309 chr11:58395628 NA -0.71 -8.73 -0.43 1.11e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9399135 0.967 rs13191501 chr6:135366880 T/C cg24558204 chr6:135376177 HBS1L 0.42 6.77 0.34 5.57e-11 Red blood cell count; LIHC trans rs2727020 0.658 rs7111215 chr11:49430552 T/C cg03929089 chr4:120376271 NA -0.85 -16.42 -0.66 4.29e-45 Coronary artery disease; LIHC trans rs11098499 0.754 rs2964 chr4:120240131 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg22373622 chr1:1489544 SSU72 -0.55 -7.06 -0.36 9.38e-12 Alcohol dependence; LIHC cis rs7940866 0.903 rs1347283 chr11:130868583 T/G cg12179176 chr11:130786555 SNX19 0.51 7.27 0.37 2.47e-12 Schizophrenia; LIHC cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC trans rs35110281 0.627 rs6518268 chr21:44967448 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.68 0.34 9.59e-11 Mean corpuscular volume; LIHC cis rs9303401 0.538 rs12603174 chr17:56489279 T/C cg25039879 chr17:56429692 SUPT4H1 0.79 9.27 0.45 2.08e-18 Cognitive test performance; LIHC cis rs9393692 0.645 rs11756673 chr6:26323505 A/G cg13736514 chr6:26305472 NA -0.4 -6.2 -0.32 1.66e-9 Educational attainment; LIHC cis rs2629540 0.847 rs12763093 chr10:126395688 C/G cg20435097 chr10:126320824 FAM53B 0.43 6.29 0.32 9.91e-10 Cocaine dependence; LIHC cis rs9467711 0.559 rs12176129 chr6:26514940 C/T cg12826209 chr6:26865740 GUSBL1 0.59 5.98 0.31 5.71e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs67311347 1.000 rs9834052 chr3:40399060 G/A cg13409248 chr3:40428643 ENTPD3 0.4 6.64 0.34 1.2e-10 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02539911 chr17:58677246 PPM1D 0.43 6.11 0.31 2.76e-9 Pancreatic cancer; LIHC cis rs5769765 0.908 rs4058453 chr22:50250297 T/C cg09182678 chr22:50328711 NA 0.49 6.13 0.31 2.4e-9 Schizophrenia; LIHC cis rs4788570 0.609 rs72795869 chr16:71485515 C/T cg06353428 chr16:71660113 MARVELD3 -1.11 -10.1 -0.48 3.73e-21 Intelligence (multi-trait analysis); LIHC cis rs4665809 1.000 rs4233708 chr2:26291345 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.84 -0.43 5.01e-17 Gut microbiome composition (summer); LIHC cis rs7044106 0.762 rs10739570 chr9:123381222 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.85 0.51 9.4e-24 Hip circumference adjusted for BMI; LIHC cis rs6912958 0.935 rs6454629 chr6:88165515 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.19 -0.36 4.09e-12 Monocyte percentage of white cells; LIHC cis rs3736485 0.903 rs11070863 chr15:51904590 A/C cg08986416 chr15:51914746 DMXL2 -0.42 -5.87 -0.3 1.05e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9473924 0.542 rs35546156 chr6:50829785 C/T cg14470998 chr6:50812995 TFAP2B 0.96 10.84 0.51 9.97e-24 Body mass index; LIHC cis rs2176862 1.000 rs115595413 chr3:46612022 G/A cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.34 -0.32 7.42e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs1878931 0.582 rs4785933 chr16:3419741 T/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.67 8.74 0.43 1.08e-16 Body mass index (adult); LIHC cis rs950169 0.922 rs12910334 chr15:84958318 G/A cg12863693 chr15:85201151 NMB 0.42 5.8 0.3 1.5e-8 Schizophrenia; LIHC cis rs4073582 0.595 rs801731 chr11:65938446 G/C cg14036092 chr11:66035641 RAB1B 0.42 6.34 0.32 7.17e-10 Gout; LIHC cis rs3096299 0.606 rs4785674 chr16:89536613 A/G cg02187348 chr16:89574699 SPG7 0.44 6.03 0.31 4.16e-9 Multiple myeloma (IgH translocation); LIHC cis rs5769707 0.935 rs9616332 chr22:50047678 C/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.71 -0.43 1.28e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.58 11.05 0.51 1.79e-24 Prudent dietary pattern; LIHC cis rs2075371 1.000 rs378358 chr7:133970628 A/G cg20476274 chr7:133979776 SLC35B4 0.77 13.3 0.58 8.29e-33 Mean platelet volume; LIHC trans rs10242455 0.850 rs57367781 chr7:99116819 G/A cg09045935 chr12:6379348 NA 0.84 6.92 0.35 2.28e-11 Blood metabolite levels; LIHC cis rs7647973 0.925 rs9881860 chr3:49352522 A/T cg07636037 chr3:49044803 WDR6 0.5 6.0 0.31 5.13e-9 Menarche (age at onset); LIHC cis rs854765 0.647 rs4426402 chr17:17977926 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.38 -6.86 -0.35 3.32e-11 Total body bone mineral density; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.97 0.8 4.49e-79 Prudent dietary pattern; LIHC cis rs10416265 0.528 rs17884930 chr19:33595390 A/G cg27124370 chr19:33622961 WDR88 0.49 6.87 0.35 3e-11 Bone properties (heel); LIHC cis rs9810089 0.814 rs73226190 chr3:136213310 T/C cg21827317 chr3:136751795 NA 0.46 6.19 0.32 1.74e-9 Gestational age at birth (child effect); LIHC cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg18357526 chr6:26021779 HIST1H4A 0.58 8.04 0.4 1.49e-14 Blood metabolite levels; LIHC cis rs8016982 0.674 rs11159494 chr14:81667611 G/C cg01989461 chr14:81687754 GTF2A1 0.71 14.77 0.62 1.55e-38 Schizophrenia; LIHC cis rs7428 0.545 rs1053561 chr2:85546052 A/G cg24342717 chr2:85555507 TGOLN2 -0.76 -10.69 -0.5 3.24e-23 Ear protrusion; LIHC cis rs4901869 0.902 rs2162491 chr14:59296247 C/T cg02291164 chr14:59296302 NA 0.49 6.66 0.34 1.11e-10 Panic disorder; LIHC trans rs2727020 0.688 rs11040338 chr11:49360601 A/G cg03929089 chr4:120376271 NA 0.82 14.64 0.62 4.93e-38 Coronary artery disease; LIHC cis rs1003719 0.788 rs2835597 chr21:38466539 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg16132339 chr22:24313637 DDTL;DDT 0.76 14.28 0.61 1.29e-36 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg27170947 chr2:26402098 FAM59B -0.71 -8.69 -0.43 1.54e-16 Gut microbiome composition (summer); LIHC cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.63 6.18 0.32 1.81e-9 Platelet count; LIHC cis rs17253792 0.915 rs78498383 chr14:56177585 C/T cg01858014 chr14:56050164 KTN1 -0.76 -8.08 -0.4 1.1e-14 Putamen volume; LIHC cis rs4700695 0.841 rs152933 chr5:65359530 A/G cg21114390 chr5:65439923 SFRS12 -0.46 -5.93 -0.31 7.4e-9 Facial morphology (factor 19); LIHC cis rs13394619 0.533 rs12615856 chr2:11746177 C/T cg07314298 chr2:11723111 GREB1 0.36 6.07 0.31 3.4e-9 Endometriosis; LIHC cis rs262150 0.625 rs117651953 chr7:158780563 G/A cg25332918 chr7:158766061 NA -0.39 -6.01 -0.31 4.8e-9 Facial morphology (factor 20); LIHC cis rs12477438 0.520 rs11123764 chr2:99750677 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.21 21.25 0.75 1.75e-64 Chronic sinus infection; LIHC cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg19729930 chr2:74357872 NA 0.8 17.63 0.69 5.84e-50 Gestational age at birth (maternal effect); LIHC cis rs5758659 1.000 rs134902 chr22:42683997 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.35 -6.65 -0.34 1.18e-10 Cognitive function; LIHC cis rs74181299 0.653 rs2723091 chr2:65302017 C/T cg05010058 chr2:65284262 CEP68 0.39 6.46 0.33 3.55e-10 Pulse pressure; LIHC cis rs2334880 0.678 rs66778248 chr16:71451424 A/G cg06353428 chr16:71660113 MARVELD3 -0.89 -8.37 -0.41 1.52e-15 Malaria; LIHC cis rs12744310 0.887 rs28399806 chr1:41784971 C/T cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.92e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11673344 0.864 rs2562595 chr19:37514866 A/T cg27390819 chr19:37464633 NA -0.52 -6.38 -0.33 5.73e-10 Obesity-related traits; LIHC cis rs34779708 0.931 rs72789687 chr10:35372489 G/A cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs600806 0.888 rs11102971 chr1:109872370 C/T cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.31 -0.37 1.89e-12 Intelligence (multi-trait analysis); LIHC cis rs17102423 0.654 rs8015921 chr14:65523015 G/A cg16583315 chr14:65563665 MAX -0.37 -7.12 -0.36 6.39e-12 Obesity-related traits; LIHC cis rs5769707 0.632 rs135872 chr22:50009300 T/C cg07959070 chr22:50026188 C22orf34 -0.34 -8.69 -0.43 1.49e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg00149659 chr3:10157352 C3orf10 0.68 7.11 0.36 6.86e-12 Alzheimer's disease; LIHC cis rs67981189 0.513 rs221893 chr14:71611414 G/A cg15816911 chr14:71606274 NA -0.45 -7.16 -0.36 4.99e-12 Schizophrenia; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.0 20.47 0.74 2.34e-61 Height; LIHC cis rs2806561 0.765 rs1738470 chr1:23511911 G/A cg12483005 chr1:23474871 LUZP1 0.45 7.16 0.36 5.1e-12 Height; LIHC cis rs116095464 0.681 rs9687745 chr5:229309 C/T cg22857025 chr5:266934 NA -1.48 -18.29 -0.7 1.38e-52 Breast cancer; LIHC cis rs4891159 0.790 rs17059325 chr18:74119567 A/C cg24786174 chr18:74118243 ZNF516 -0.75 -12.45 -0.56 1.37e-29 Longevity; LIHC cis rs4969178 0.930 rs12452576 chr17:76386037 A/C cg20026190 chr17:76395443 PGS1 0.46 7.21 0.36 3.52e-12 HDL cholesterol levels; LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg18306943 chr3:40428807 ENTPD3 0.43 7.6 0.38 2.94e-13 Renal cell carcinoma; LIHC cis rs7095607 0.630 rs7069569 chr10:69955140 T/A cg18986048 chr10:69913749 MYPN 0.39 5.81 0.3 1.46e-8 Lung function (FVC); LIHC cis rs2412488 0.927 rs12649718 chr4:54259862 C/T cg22241045 chr4:54363911 LNX1 -0.41 -6.62 -0.34 1.36e-10 DNA methylation (variation); LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.25 -0.32 1.25e-9 Total body bone mineral density; LIHC cis rs4908768 0.501 rs1922983 chr1:8531326 A/G cg20416874 chr1:8611966 RERE -0.67 -14.35 -0.61 7.27e-37 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2197308 0.655 rs1971964 chr12:37870474 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs6693567 0.565 rs11205370 chr1:150397567 A/G cg15654264 chr1:150340011 RPRD2 0.49 8.18 0.4 5.54e-15 Migraine; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25542733 chr7:73256925 WBSCR27 0.45 6.24 0.32 1.33e-9 Lung function (FEV1/FVC); LIHC cis rs1144333 0.522 rs1144338 chr1:76279908 T/C cg22875332 chr1:76189707 ACADM -0.36 -6.03 -0.31 4.37e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC cis rs4843747 0.671 rs72818576 chr16:88111019 C/G cg00677901 chr16:88017247 BANP 0.53 8.14 0.4 7.67e-15 Menopause (age at onset); LIHC cis rs7772486 0.754 rs9386132 chr6:146140751 T/C cg13319975 chr6:146136371 FBXO30 -0.41 -6.73 -0.34 7.07e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg21782813 chr7:2030301 MAD1L1 0.4 6.69 0.34 8.97e-11 Bipolar disorder and schizophrenia; LIHC cis rs12824058 0.831 rs12314111 chr12:130813663 G/T cg24229701 chr12:130821962 PIWIL1 0.44 6.82 0.35 4.19e-11 Menopause (age at onset); LIHC cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg23172400 chr8:95962367 TP53INP1 -0.42 -9.79 -0.47 4.01e-20 Type 2 diabetes; LIHC cis rs826838 0.967 rs11183514 chr12:38760744 A/T cg13010199 chr12:38710504 ALG10B 0.64 7.62 0.38 2.59e-13 Heart rate; LIHC cis rs941873 0.868 rs2181080 chr10:81121960 A/G cg09469691 chr10:81107165 PPIF 0.71 10.49 0.49 1.66e-22 Height; LIHC cis rs9916302 0.904 rs7223438 chr17:37521355 T/C cg00129232 chr17:37814104 STARD3 0.4 6.34 0.32 7.08e-10 Glomerular filtration rate (creatinine); LIHC cis rs798554 0.797 rs2107964 chr7:2863574 G/A cg19717773 chr7:2847554 GNA12 -0.47 -7.12 -0.36 6.23e-12 Height; LIHC cis rs6061231 0.505 rs13037253 chr20:60928724 G/A cg24112000 chr20:60950667 NA -0.44 -5.75 -0.3 2.01e-8 Colorectal cancer; LIHC cis rs7208859 0.623 rs73263788 chr17:29216490 T/C cg13385521 chr17:29058706 SUZ12P 0.79 7.88 0.39 4.55e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2439831 0.867 rs3101443 chr15:43912372 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.66 9.19 0.44 4.03e-18 Lung cancer in ever smokers; LIHC cis rs6867032 0.874 rs4975786 chr5:2004724 T/C cg26168224 chr5:2018326 NA -0.29 -7.13 -0.36 6.09e-12 Gut microbiome composition (winter); LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg05603623 chr19:8008081 TIMM44 -0.56 -6.19 -0.32 1.7e-9 Bronchial neuroendocrine tumor; LIHC cis rs919433 0.617 rs10931793 chr2:198577585 G/A cg10820045 chr2:198174542 NA -0.51 -7.82 -0.39 6.65e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17376456 0.866 rs13356088 chr5:93423479 C/T cg25358565 chr5:93447407 FAM172A 0.99 7.18 0.36 4.46e-12 Diabetic retinopathy; LIHC cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg26531700 chr6:26746687 NA 0.39 6.49 0.33 3.05e-10 Intelligence (multi-trait analysis); LIHC cis rs2224391 0.704 rs17139985 chr6:5261603 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.42 -6.28 -0.32 1.02e-9 Height; LIHC cis rs2795502 0.554 rs1620395 chr10:43341185 G/A cg20628663 chr10:43360327 NA -0.39 -6.96 -0.35 1.77e-11 Blood protein levels; LIHC cis rs4713118 0.866 rs2179094 chr6:27741825 T/C cg20933634 chr6:27740509 NA 0.45 6.03 0.31 4.2e-9 Parkinson's disease; LIHC cis rs4713118 0.824 rs9468225 chr6:27745719 T/G cg20933634 chr6:27740509 NA 0.45 5.99 0.31 5.41e-9 Parkinson's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11699593 chr8:22102731 POLR3D;MIR320A 0.44 6.05 0.31 3.87e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 0.882 rs67631672 chr3:10004768 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.28 -0.45 1.96e-18 Alzheimer's disease; LIHC cis rs9309473 0.519 rs13009035 chr2:73845709 T/C cg20560298 chr2:73613845 ALMS1 0.35 5.73 0.3 2.22e-8 Metabolite levels; LIHC cis rs67311347 0.866 rs1454491 chr3:40352647 C/G cg18306943 chr3:40428807 ENTPD3 0.34 5.73 0.3 2.16e-8 Renal cell carcinoma; LIHC cis rs3761847 0.622 rs10818500 chr9:123810883 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.42 -5.85 -0.3 1.15e-8 Rheumatoid arthritis; LIHC cis rs1023500 0.505 rs2143139 chr22:42614401 G/C cg04733989 chr22:42467013 NAGA 0.41 6.22 0.32 1.48e-9 Schizophrenia; LIHC cis rs2412488 0.893 rs11133276 chr4:54369040 G/A cg22241045 chr4:54363911 LNX1 -0.39 -6.25 -0.32 1.2e-9 DNA methylation (variation); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11733266 chr13:99096847 FARP1 0.41 6.06 0.31 3.64e-9 Immature fraction of reticulocytes; LIHC cis rs9911578 1.000 rs12940681 chr17:56933622 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.81 -0.43 6.54e-17 Intelligence (multi-trait analysis); LIHC cis rs568617 1.000 rs641018 chr11:65655393 G/C cg04055107 chr11:65626734 MUS81;CFL1 0.44 6.44 0.33 4.17e-10 Crohn's disease; LIHC trans rs7613875 0.620 rs2526747 chr3:50082914 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.43 6.45 0.33 3.88e-10 Body mass index; LIHC cis rs7617480 0.616 rs7429596 chr3:48808531 T/C cg07636037 chr3:49044803 WDR6 0.76 9.01 0.44 1.49e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs7903847 0.642 rs7909345 chr10:99150794 T/C cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.53e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs4722166 0.508 rs1474347 chr7:22768124 A/C cg05472934 chr7:22766657 IL6 -0.51 -8.31 -0.41 2.23e-15 Lung cancer; LIHC cis rs727505 0.954 rs1014163 chr7:124443604 G/A cg23710748 chr7:124431027 NA -0.35 -6.2 -0.32 1.62e-9 Lewy body disease; LIHC cis rs1348850 0.668 rs13010396 chr2:178492934 T/C cg27490568 chr2:178487706 NA 0.7 9.3 0.45 1.76e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg00080972 chr5:178986291 RUFY1 0.39 5.88 0.3 1e-8 Lung cancer; LIHC cis rs2108622 0.727 rs12610967 chr19:15977929 C/A cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.87e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21506059 chr17:65242309 HELZ -0.39 -6.06 -0.31 3.68e-9 Pancreatic cancer; LIHC cis rs9916302 0.800 rs9892675 chr17:37549200 C/T cg07936489 chr17:37558343 FBXL20 0.89 13.79 0.6 1.05e-34 Glomerular filtration rate (creatinine); LIHC cis rs2932538 0.846 rs7546203 chr1:113154529 C/A cg22162597 chr1:113214053 CAPZA1 0.73 11.15 0.52 7.68e-25 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs4650994 1.000 rs4650994 chr1:178515312 A/G cg05059571 chr16:84539110 KIAA1609 0.38 6.41 0.33 4.87e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2274273 1.000 rs2075603 chr14:55609955 C/A cg01864836 chr14:55583639 NA -0.36 -6.15 -0.32 2.14e-9 Protein biomarker; LIHC cis rs933688 1.000 rs60513756 chr5:90727692 A/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.17 0.66 4.52e-44 Smoking behavior; LIHC cis rs6977660 0.714 rs10228783 chr7:19789290 C/T cg07541023 chr7:19748670 TWISTNB 0.49 7.38 0.37 1.18e-12 Thyroid stimulating hormone; LIHC cis rs6942756 0.915 rs6966595 chr7:129006202 A/C cg02491457 chr7:128862824 NA -0.59 -8.9 -0.43 3.42e-17 White matter hyperintensity burden; LIHC cis rs9908158 1 rs9908158 chr17:33890083 T/C cg20932281 chr17:33905541 PEX12 0.42 5.77 0.3 1.78e-8 Platelet count;Platelet distribution width; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg15219393 chr5:149109878 PPARGC1B 0.6 7.85 0.39 5.45e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10659575 chr11:102188233 BIRC3 0.49 7.22 0.36 3.46e-12 Pancreatic cancer; LIHC cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg03806693 chr22:41940476 POLR3H 0.98 10.53 0.49 1.23e-22 Vitiligo; LIHC cis rs1062177 0.855 rs62395861 chr5:151269270 A/G cg00977110 chr5:151150581 G3BP1 0.49 6.25 0.32 1.22e-9 Preschool internalizing problems; LIHC trans rs7613875 0.641 rs2624845 chr3:50062437 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.61 -0.34 1.46e-10 Body mass index; LIHC cis rs561341 1.000 rs550264 chr17:30317540 G/T cg00745463 chr17:30367425 LRRC37B -0.77 -5.73 -0.3 2.16e-8 Hip circumference adjusted for BMI; LIHC cis rs920590 0.721 rs67989257 chr8:19660278 G/A cg01411142 chr8:19674711 INTS10 0.5 7.6 0.38 2.79e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs67311347 1.000 rs9848083 chr3:40466979 A/G cg00656387 chr3:40428638 ENTPD3 -0.44 -7.49 -0.38 6.11e-13 Renal cell carcinoma; LIHC trans rs911555 0.692 rs7140647 chr14:103893465 A/G cg17675199 chr6:35436792 RPL10A -0.42 -8.54 -0.42 4.58e-16 Intelligence (multi-trait analysis); LIHC cis rs826838 0.585 rs12296822 chr12:38625829 A/T cg26384229 chr12:38710491 ALG10B -0.51 -7.08 -0.36 8.34e-12 Heart rate; LIHC cis rs4803468 0.967 rs892044 chr19:41903671 A/G cg09537434 chr19:41945824 ATP5SL -1.0 -20.81 -0.75 9.66e-63 Height; LIHC trans rs9914544 0.545 rs34417974 chr17:18773636 T/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.54 -0.33 2.19e-10 Educational attainment (years of education); LIHC cis rs1005277 0.522 rs289645 chr10:37943642 T/C cg25427524 chr10:38739819 LOC399744 -0.6 -11.32 -0.52 1.94e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9326248 1.000 rs9326248 chr11:116999225 A/C cg11861562 chr11:117069780 TAGLN 0.47 7.76 0.39 9.76e-14 Blood protein levels; LIHC cis rs2075371 0.829 rs9641970 chr7:134004887 C/A cg20476274 chr7:133979776 SLC35B4 0.68 9.19 0.44 3.98e-18 Mean platelet volume; LIHC cis rs3018712 0.532 rs57813595 chr11:68402606 C/G cg16797656 chr11:68205561 LRP5 0.5 6.22 0.32 1.45e-9 Total body bone mineral density; LIHC cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg24209194 chr3:40518798 ZNF619 0.44 6.28 0.32 1.05e-9 Renal cell carcinoma; LIHC cis rs1728785 1.000 rs12925177 chr16:68569645 A/G cg02972257 chr16:68554789 NA 0.57 6.65 0.34 1.17e-10 Ulcerative colitis; LIHC cis rs9534288 0.830 rs1548325 chr13:46635101 A/G cg15192986 chr13:46630673 CPB2 -0.59 -8.7 -0.43 1.46e-16 Blood protein levels; LIHC cis rs9549367 0.789 rs9549698 chr13:113877701 A/G cg18105134 chr13:113819100 PROZ -0.68 -11.85 -0.54 2.3e-27 Platelet distribution width; LIHC cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs8062405 0.895 rs62036658 chr16:28850371 T/G cg16576597 chr16:28551801 NUPR1 0.36 5.72 0.3 2.32e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs16866061 0.926 rs1523919 chr2:225403615 G/A cg12698349 chr2:225449008 CUL3 0.8 13.53 0.59 1.09e-33 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs9372253 1.000 rs9384740 chr6:110716207 G/A cg01119278 chr6:110721349 DDO -0.31 -6.53 -0.33 2.32e-10 Platelet distribution width; LIHC cis rs3741404 0.757 rs2282492 chr11:63918589 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.93 15.52 0.64 1.62e-41 Platelet count; LIHC cis rs367615 0.704 rs7726991 chr5:108847434 C/T cg17395555 chr5:108820864 NA 0.4 8.8 0.43 7.12e-17 Colorectal cancer (SNP x SNP interaction); LIHC cis rs6121246 0.954 rs7266148 chr20:30431070 G/T cg13852791 chr20:30311386 BCL2L1 0.92 9.28 0.45 2.02e-18 Mean corpuscular hemoglobin; LIHC cis rs722599 0.683 rs10139016 chr14:75274288 T/C cg08847533 chr14:75593920 NEK9 0.54 8.24 0.41 3.59e-15 IgG glycosylation; LIHC cis rs16828019 0.929 rs4131949 chr1:41738637 C/T cg20697417 chr1:41786797 NA 0.35 6.59 0.34 1.71e-10 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.76e-9 Menopause (age at onset); LIHC cis rs2075371 0.829 rs35897155 chr7:134002711 G/A cg11752832 chr7:134001865 SLC35B4 0.45 5.82 0.3 1.33e-8 Mean platelet volume; LIHC cis rs600806 0.778 rs4970761 chr1:109995398 C/T cg16275483 chr1:110013120 SYPL2 -0.47 -5.83 -0.3 1.27e-8 Intelligence (multi-trait analysis); LIHC cis rs910316 1.000 rs175512 chr14:75523382 T/C cg08847533 chr14:75593920 NEK9 -0.9 -19.8 -0.73 1.09e-58 Height; LIHC cis rs826838 1.000 rs34254519 chr12:39041235 G/A cg26384229 chr12:38710491 ALG10B 0.9 11.93 0.54 1.14e-27 Heart rate; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09997638 chr19:17530742 FAM125A 0.62 8.18 0.4 5.59e-15 Lung function (FEV1/FVC); LIHC cis rs10078 0.848 rs890985 chr5:479746 C/G cg26072250 chr5:443457 EXOC3;C5orf55 0.53 7.15 0.36 5.23e-12 Fat distribution (HIV); LIHC cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg06634786 chr22:41940651 POLR3H 0.83 8.96 0.44 2.12e-17 Vitiligo; LIHC cis rs12701220 0.655 rs7784403 chr7:1153077 G/A cg18765753 chr7:1198926 ZFAND2A -0.45 -6.25 -0.32 1.22e-9 Bronchopulmonary dysplasia; LIHC cis rs11792861 0.816 rs17792434 chr9:111667319 C/T cg13535736 chr9:111863775 C9orf5 -0.37 -5.75 -0.3 1.95e-8 Menarche (age at onset); LIHC cis rs12824058 0.831 rs12829373 chr12:130814114 G/C cg24838063 chr12:130822603 PIWIL1 0.66 9.79 0.47 4.16e-20 Menopause (age at onset); LIHC cis rs9814567 1.000 rs11706117 chr3:134212526 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.93 -0.31 7.42e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9814567 0.752 rs13064209 chr3:134335993 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 9.1 0.44 7.53e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1691799 0.867 rs1027400 chr12:66760922 A/T cg16791601 chr12:66731901 HELB -0.48 -10.24 -0.48 1.19e-21 White blood cell count (basophil); LIHC cis rs3008870 1.000 rs2815357 chr1:67491854 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.15 0.66 5.24e-44 Lymphocyte percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13457890 chr11:804976 LRDD 0.43 6.42 0.33 4.64e-10 Lung function (FEV1/FVC); LIHC cis rs11758351 1.000 rs79264785 chr6:26194121 C/T cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.55 7.77 0.39 9.31e-14 Lymphocyte counts; LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs5769707 0.681 rs1107514 chr22:50042383 T/C cg01652190 chr22:50026171 C22orf34 -0.35 -7.75 -0.39 1.03e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs3806843 0.705 rs2530230 chr5:140088131 G/A cg26395211 chr5:140044315 WDR55 0.39 5.73 0.3 2.17e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs317689 0.690 rs570256 chr12:69662929 A/T cg19645103 chr12:69753606 YEATS4 -0.44 -5.9 -0.3 8.78e-9 Response to diuretic therapy; LIHC cis rs2380220 0.872 rs67846436 chr6:95951521 G/T cg15832292 chr6:96025679 MANEA -0.6 -6.63 -0.34 1.3e-10 Behavioural disinhibition (generation interaction); LIHC cis rs8180040 0.764 rs13084117 chr3:47183239 C/A cg02527881 chr3:46936655 PTH1R -0.32 -6.33 -0.32 7.83e-10 Colorectal cancer; LIHC trans rs561341 1.000 rs117979353 chr17:30272866 A/G cg20587970 chr11:113659929 NA -1.46 -11.99 -0.54 6.92e-28 Hip circumference adjusted for BMI; LIHC cis rs2243480 0.706 rs34466769 chr7:65453292 A/C cg07424592 chr7:64974309 NA 0.65 8.17 0.4 6.03e-15 Diabetic kidney disease; LIHC cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg10295955 chr4:187884368 NA -0.97 -22.14 -0.77 5.02e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs4474465 0.688 rs7937225 chr11:78278126 T/A cg02023728 chr11:77925099 USP35 -0.33 -5.8 -0.3 1.55e-8 Alzheimer's disease (survival time); LIHC cis rs950027 0.620 rs1145077 chr15:45683795 A/C cg26924012 chr15:45694286 SPATA5L1 -0.73 -11.07 -0.51 1.5e-24 Response to fenofibrate (adiponectin levels); LIHC cis rs4919087 0.748 rs701816 chr10:98977250 C/T cg25902810 chr10:99078978 FRAT1 -0.56 -6.36 -0.33 6.41e-10 Monocyte count; LIHC cis rs2549003 1.000 rs2706384 chr5:131826880 G/T cg02551604 chr5:131831745 NA 0.46 6.83 0.35 3.78e-11 Asthma (sex interaction); LIHC cis rs909002 0.849 rs6664789 chr1:32072406 C/G cg13919466 chr1:32135498 COL16A1 -0.3 -5.96 -0.31 6.35e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg09455208 chr3:40491958 NA -0.41 -8.42 -0.41 1.02e-15 Renal cell carcinoma; LIHC cis rs9420 0.961 rs12804972 chr11:57463767 T/C cg19752551 chr11:57585705 CTNND1 -0.53 -7.39 -0.37 1.16e-12 Schizophrenia; LIHC cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg11279151 chr3:101281821 RG9MTD1 -0.53 -7.92 -0.39 3.35e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs11971779 0.793 rs4728464 chr7:139017670 C/T cg07862535 chr7:139043722 LUC7L2 -0.63 -10.94 -0.51 4.5e-24 Diisocyanate-induced asthma; LIHC cis rs208520 0.955 rs9453664 chr6:66976079 A/C cg07460842 chr6:66804631 NA 0.68 7.23 0.36 3.16e-12 Exhaled nitric oxide output; LIHC cis rs6912958 0.559 rs173333 chr6:88047754 T/G cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.94 0.51 4.23e-24 Monocyte percentage of white cells; LIHC cis rs873946 0.586 rs11146503 chr10:134565388 T/C cg27286337 chr10:134555280 INPP5A 0.89 12.44 0.56 1.44e-29 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1728785 1.000 rs7192341 chr16:68569224 G/C cg02972257 chr16:68554789 NA -0.55 -6.28 -0.32 1.04e-9 Ulcerative colitis; LIHC cis rs7633770 0.786 rs1607737 chr3:46681846 G/C cg11219411 chr3:46661640 NA 0.45 8.02 0.4 1.73e-14 Coronary artery disease; LIHC cis rs7592578 0.679 rs62181020 chr2:191325601 A/C cg10560079 chr2:191398806 TMEM194B -0.77 -11.2 -0.52 5.3e-25 Diastolic blood pressure; LIHC trans rs1509701 0.773 rs61834561 chr1:239198199 T/G cg02310027 chr17:77704741 ENPP7 0.42 6.36 0.33 6.59e-10 Shingles; LIHC cis rs8192917 1.000 rs2273844 chr14:25103414 G/A cg08766149 chr14:25103301 GZMB 0.33 7.58 0.38 3.18e-13 Vitiligo; LIHC trans rs2727020 0.729 rs4980439 chr11:49342246 G/C cg15704280 chr7:45808275 SEPT13 -0.93 -17.24 -0.68 2.31e-48 Coronary artery disease; LIHC cis rs2559856 1.000 rs2695286 chr12:102088507 T/C cg12924262 chr12:102091054 CHPT1 0.52 8.28 0.41 2.89e-15 Blood protein levels; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/T cg23422044 chr7:1970798 MAD1L1 -0.73 -6.3 -0.32 9.12e-10 Bipolar disorder and schizophrenia; LIHC trans rs10411161 0.702 rs17778790 chr19:52399559 C/T cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg19729930 chr2:74357872 NA 0.8 17.61 0.69 7.36e-50 Gestational age at birth (maternal effect); LIHC cis rs9300255 0.602 rs1616181 chr12:123619856 T/A cg00376283 chr12:123451042 ABCB9 0.58 6.44 0.33 4.09e-10 Neutrophil percentage of white cells; LIHC cis rs875971 0.965 rs28682868 chr7:65689809 C/T cg11764359 chr7:65958608 NA -0.88 -15.37 -0.64 6.43e-41 Aortic root size; LIHC cis rs6951245 1.000 rs75488469 chr7:1102122 A/G cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.89e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2243480 0.706 rs34466769 chr7:65453292 A/C cg11764359 chr7:65958608 NA 0.54 6.26 0.32 1.17e-9 Diabetic kidney disease; LIHC cis rs7772486 0.654 rs702321 chr6:146006695 A/G cg23711669 chr6:146136114 FBXO30 -0.64 -11.54 -0.53 2.94e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs12549902 0.932 rs6981607 chr8:41508168 A/C cg21772509 chr8:41503840 NKX6-3 0.43 6.96 0.35 1.74e-11 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg21782813 chr7:2030301 MAD1L1 -0.55 -10.09 -0.48 3.98e-21 Bipolar disorder and schizophrenia; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg00091569 chr3:40428383 ENTPD3 -0.39 -6.56 -0.33 2.01e-10 Renal cell carcinoma; LIHC cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg17971929 chr21:40555470 PSMG1 0.85 10.16 0.48 2.26e-21 Cognitive function; LIHC cis rs35110281 0.744 rs230644 chr21:44917183 C/T cg04455712 chr21:45112962 RRP1B -0.46 -7.6 -0.38 2.86e-13 Mean corpuscular volume; LIHC cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 7.07 0.36 8.84e-12 Bipolar disorder; LIHC cis rs35306767 0.855 rs11253459 chr10:886402 C/T cg26597838 chr10:835615 NA 1.11 13.81 0.6 9.05e-35 Eosinophil percentage of granulocytes; LIHC cis rs7131987 0.650 rs67146951 chr12:29450553 C/A cg12903224 chr12:29470962 FAR2 -0.42 -6.81 -0.35 4.31e-11 QT interval; LIHC cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg06108461 chr20:60628389 TAF4 -1.03 -18.01 -0.7 1.74e-51 Body mass index; LIHC cis rs17818399 0.547 rs7607308 chr2:46759104 T/C cg02822958 chr2:46747628 ATP6V1E2 0.43 6.32 0.32 7.96e-10 Height; LIHC cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs1707322 0.963 rs4459051 chr1:46451203 A/G cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg14004847 chr7:1930337 MAD1L1 -0.42 -6.1 -0.31 2.86e-9 Bipolar disorder and schizophrenia; LIHC cis rs6867032 0.570 rs13166888 chr5:1982966 G/T cg26168224 chr5:2018326 NA -0.26 -5.83 -0.3 1.27e-8 Gut microbiome composition (winter); LIHC cis rs9640161 0.789 rs1464751 chr7:150021282 C/T cg10018233 chr7:150070692 REPIN1 0.57 9.62 0.46 1.49e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs611744 0.647 rs11785776 chr8:109264933 C/T cg21045802 chr8:109455806 TTC35 0.59 10.37 0.49 4.22e-22 Dupuytren's disease; LIHC cis rs2115630 1.000 rs4633690 chr15:85361960 C/T cg12501888 chr15:85177176 SCAND2 -0.5 -7.68 -0.38 1.69e-13 P wave terminal force; LIHC cis rs710216 0.843 rs3768043 chr1:43419354 C/A cg03128534 chr1:43423976 SLC2A1 -0.51 -7.21 -0.36 3.58e-12 Red cell distribution width; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05330977 chr17:18154724 FLII -0.42 -6.28 -0.32 1.01e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 0.850 rs11076619 chr16:89831243 C/A cg06558623 chr16:89946397 TCF25 0.85 11.71 0.53 7.62e-27 Skin colour saturation; LIHC cis rs506338 0.517 rs17146216 chr11:64451281 C/G cg03263716 chr11:64435066 NRXN2 0.33 7.02 0.36 1.17e-11 Body mass index;Urate levels; LIHC cis rs10847980 0.623 rs7955367 chr12:123828792 G/A cg00376283 chr12:123451042 ABCB9 0.62 6.53 0.33 2.41e-10 Adiponectin levels; LIHC cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg21724239 chr8:58056113 NA 0.58 7.23 0.36 3.14e-12 Developmental language disorder (linguistic errors); LIHC cis rs8062405 1.000 rs62036616 chr16:28826307 A/G cg16576597 chr16:28551801 NUPR1 0.37 5.86 0.3 1.11e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11031096 0.754 rs10835611 chr11:4117730 G/C cg18678763 chr11:4115507 RRM1 -0.51 -7.83 -0.39 6.34e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs13118159 0.651 rs4974599 chr4:1314430 A/C cg20887711 chr4:1340912 KIAA1530 0.62 9.34 0.45 1.28e-18 Longevity; LIHC cis rs7772486 0.875 rs56181683 chr6:146286620 A/G cg23711669 chr6:146136114 FBXO30 -0.58 -9.77 -0.47 4.81e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs909002 0.800 rs4949454 chr1:32099041 A/G cg13919466 chr1:32135498 COL16A1 0.34 6.47 0.33 3.48e-10 Intelligence (multi-trait analysis); LIHC cis rs1691799 0.899 rs1168305 chr12:66738714 A/G cg16791601 chr12:66731901 HELB -0.57 -13.85 -0.6 6.11e-35 White blood cell count (basophil); LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg10774155 chr7:65338427 VKORC1L1 0.45 6.61 0.34 1.43e-10 Calcium levels; LIHC trans rs3749237 1.000 rs11130216 chr3:49736172 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.64 9.89 0.47 1.9e-20 Resting heart rate; LIHC cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg07308232 chr7:1071921 C7orf50 -0.49 -7.86 -0.39 5.16e-14 Longevity;Endometriosis; LIHC cis rs7897654 0.571 rs12771681 chr10:104635620 T/C cg15744005 chr10:104629667 AS3MT -0.38 -7.68 -0.38 1.66e-13 Schizophrenia; LIHC cis rs477692 1.000 rs503660 chr10:131418999 A/G cg05714579 chr10:131428358 MGMT 0.49 8.17 0.4 5.93e-15 Response to temozolomide; LIHC cis rs986417 1.000 rs6573316 chr14:61058029 C/A cg27398547 chr14:60952738 C14orf39 0.66 6.56 0.33 1.97e-10 Gut microbiota (bacterial taxa); LIHC cis rs1538970 0.924 rs7531253 chr1:45890183 T/C cg05343316 chr1:45956843 TESK2 0.57 8.37 0.41 1.49e-15 Platelet count; LIHC cis rs17125944 0.505 rs77137752 chr14:53230496 G/T cg13660082 chr14:53194042 PSMC6 -0.44 -7.65 -0.38 2e-13 Alzheimer's disease (late onset); LIHC cis rs644799 0.687 rs3748252 chr11:95519195 A/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.8 -12.56 -0.56 5.02e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg11062466 chr8:58055876 NA 0.49 7.14 0.36 5.5e-12 Developmental language disorder (linguistic errors); LIHC cis rs1355223 0.583 rs1396881 chr11:34870506 G/T cg11058730 chr11:34937778 PDHX;APIP 0.74 12.63 0.56 2.74e-30 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2832191 0.755 rs55671430 chr21:30492421 G/C cg08807101 chr21:30365312 RNF160 -0.57 -8.96 -0.44 2.14e-17 Dental caries; LIHC cis rs11190604 0.747 rs11190516 chr10:102173525 G/A cg07080220 chr10:102295463 HIF1AN 0.44 6.02 0.31 4.49e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2242116 0.727 rs6442040 chr3:46963035 C/A cg02527881 chr3:46936655 PTH1R -0.5 -10.7 -0.5 3.17e-23 Birth weight; LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg18306943 chr3:40428807 ENTPD3 0.43 7.52 0.38 4.92e-13 Renal cell carcinoma; LIHC cis rs2842992 0.958 rs2758318 chr6:160069637 C/G cg16489826 chr6:160211363 TCP1;MRPL18 0.47 7.81 0.39 7.1e-14 Age-related macular degeneration (geographic atrophy); LIHC cis rs17685 0.625 rs1639630 chr7:75730499 T/C cg04610667 chr7:75704037 NA -0.33 -5.94 -0.31 6.93e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4555082 0.834 rs2816607 chr14:105718385 A/T cg10792982 chr14:105748885 BRF1 0.5 6.56 0.33 2.05e-10 Mean platelet volume;Platelet distribution width; LIHC trans rs6598955 0.585 rs6659822 chr1:26626408 C/A cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.23 -0.41 3.96e-15 Obesity-related traits; LIHC cis rs780096 0.545 rs6716894 chr2:27583273 A/G cg27432699 chr2:27873401 GPN1 -0.49 -6.9 -0.35 2.49e-11 Total body bone mineral density; LIHC trans rs10737562 0.870 rs1928492 chr1:189583522 T/A cg21603006 chr19:1428919 DAZAP1 -0.35 -6.1 -0.31 2.9e-9 Systemic lupus erythematosus; LIHC cis rs2153535 0.563 rs1796688 chr6:8536423 A/T cg21535247 chr6:8435926 SLC35B3 0.63 8.12 0.4 8.83e-15 Motion sickness; LIHC cis rs765787 0.530 rs2413776 chr15:45544170 A/G cg25801113 chr15:45476975 SHF 0.37 6.25 0.32 1.25e-9 Uric acid levels; LIHC cis rs6952808 0.929 rs4721217 chr7:1973579 C/T cg14004847 chr7:1930337 MAD1L1 -0.44 -6.21 -0.32 1.51e-9 Bipolar disorder and schizophrenia; LIHC cis rs9549367 0.774 rs2287246 chr13:113889127 A/G cg00898013 chr13:113819073 PROZ -0.43 -7.48 -0.38 6.2800000000000005e-13 Platelet distribution width; LIHC cis rs2066819 1.000 rs2695789 chr12:56694261 C/A cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Psoriasis vulgaris; LIHC cis rs238295 0.805 rs6116855 chr20:5555317 A/G cg24001556 chr20:5591874 RP5-1022P6.2 -0.53 -7.13 -0.36 5.98e-12 Occipital cortical area (total cortical area interaction); LIHC cis rs72627509 0.680 rs66790703 chr4:57773908 G/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.54 -7.93 -0.39 3.24e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs6598955 0.724 rs869683 chr1:26570993 T/A cg00852783 chr1:26633632 UBXN11 0.5 8.32 0.41 2.16e-15 Obesity-related traits; LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg06558623 chr16:89946397 TCF25 1.01 15.53 0.64 1.55e-41 Skin colour saturation; LIHC cis rs1775715 0.737 rs2808090 chr10:32143208 A/C cg14930904 chr10:32216787 ARHGAP12 0.35 6.1 0.31 2.81e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs36022378 0.504 rs4688688 chr3:50042690 C/G cg24110177 chr3:50126178 RBM5 0.47 6.23 0.32 1.35e-9 Diastolic blood pressure; LIHC cis rs12048904 0.619 rs10875347 chr1:101333737 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.47 6.96 0.35 1.76e-11 Multiple sclerosis; LIHC cis rs317689 0.819 rs317660 chr12:69686203 G/A cg14784868 chr12:69753453 YEATS4 0.58 8.23 0.41 4.11e-15 Response to diuretic therapy; LIHC cis rs2257205 0.667 rs8071942 chr17:56778271 T/C cg12560992 chr17:57184187 TRIM37 0.72 7.97 0.4 2.33e-14 Pancreatic cancer; LIHC cis rs965469 0.947 rs7274193 chr20:3329750 C/T cg25506879 chr20:3388711 C20orf194 -0.58 -6.98 -0.35 1.59e-11 IFN-related cytopenia; LIHC cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg08219700 chr8:58056026 NA 0.53 6.95 0.35 1.88e-11 Developmental language disorder (linguistic errors); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03122602 chr16:89799836 ZNF276 0.41 6.2 0.32 1.65e-9 Longevity; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.7 11.28 0.52 2.6e-25 Prudent dietary pattern; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.69 0.62 3.3e-38 Prudent dietary pattern; LIHC cis rs2439831 1.000 rs9920763 chr15:43760508 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.69 8.8 0.43 6.95e-17 Lung cancer in ever smokers; LIHC cis rs8017423 0.967 rs7150093 chr14:90724661 C/T cg04374321 chr14:90722782 PSMC1 -0.77 -15.45 -0.64 3.1e-41 Mortality in heart failure; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg11328140 chr12:108079443 PWP1 -0.4 -6.06 -0.31 3.5e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC trans rs728616 0.681 rs12769764 chr10:81917113 C/G cg13571388 chr1:26947729 NA 0.45 6.17 0.32 1.96e-9 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs332507 0.601 rs4677938 chr3:124374259 G/A cg05980111 chr3:124395277 KALRN 0.32 6.21 0.32 1.57e-9 Plateletcrit; LIHC cis rs2637266 1.000 rs12413656 chr10:78379666 A/C cg18941641 chr10:78392320 NA 0.3 6.53 0.33 2.43e-10 Pulmonary function; LIHC cis rs9733 0.596 rs72702552 chr1:150677462 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.06e-9 Tonsillectomy; LIHC cis rs3768617 0.740 rs28533496 chr1:183019885 G/T ch.1.3577855R chr1:183094577 LAMC1 0.48 7.68 0.38 1.71e-13 Fuchs's corneal dystrophy; LIHC cis rs4979906 1.000 rs11002246 chr10:79446777 T/A cg07817648 chr10:79422355 NA -0.3 -6.4 -0.33 5.15e-10 Mortality in heart failure; LIHC cis rs1816752 0.819 rs4770665 chr13:24988948 G/A cg22771759 chr13:24902376 NA 0.3 6.02 0.31 4.43e-9 Obesity-related traits; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs950169 0.580 rs11636189 chr15:85193554 G/A cg12863693 chr15:85201151 NMB 0.49 7.09 0.36 7.55e-12 Schizophrenia; LIHC cis rs3806843 0.735 rs809635 chr5:140081791 A/G cg19875535 chr5:140030758 IK -0.41 -6.6 -0.34 1.57e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7520050 0.966 rs1085243 chr1:46544768 C/T cg03146154 chr1:46216737 IPP -0.38 -6.21 -0.32 1.51e-9 Red blood cell count;Reticulocyte count; LIHC trans rs4843747 0.518 rs4072777 chr16:88107030 G/A cg09572067 chr16:29127029 RRN3P2 0.51 8.06 0.4 1.3e-14 Menopause (age at onset); LIHC cis rs1707322 1.000 rs7526369 chr1:46390560 G/C cg06784218 chr1:46089804 CCDC17 0.34 6.03 0.31 4.19e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg10715820 chr1:17235063 NA 0.64 7.13 0.36 5.84e-12 Mean platelet volume; LIHC cis rs1005277 0.579 rs2474574 chr10:38387295 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs600806 0.778 rs2039694 chr1:109991700 A/G cg11161837 chr1:110010384 SYPL2 0.44 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.557 rs2983338 chr10:38550734 C/T cg17830980 chr10:43048298 ZNF37B -0.49 -9.45 -0.46 5.63e-19 Extrinsic epigenetic age acceleration; LIHC cis rs4957048 0.577 rs56294732 chr5:568144 T/C cg09021430 chr5:549028 NA -0.42 -8.79 -0.43 7.26e-17 Ulcerative colitis; LIHC cis rs34172651 0.517 rs874484 chr16:24803242 T/C cg00152838 chr16:24741724 TNRC6A -0.51 -5.99 -0.31 5.22e-9 Intelligence (multi-trait analysis); LIHC cis rs798554 0.797 rs798497 chr7:2795957 A/G cg04166393 chr7:2884313 GNA12 0.45 6.28 0.32 1.02e-9 Height; LIHC cis rs950169 0.922 rs67804993 chr15:85104030 T/G cg17507749 chr15:85114479 UBE2QP1 0.77 9.17 0.44 4.45e-18 Schizophrenia; LIHC cis rs6840360 0.967 rs17027798 chr4:152597540 A/G cg22705602 chr4:152727874 NA -0.29 -6.31 -0.32 8.61e-10 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg21724239 chr8:58056113 NA 0.63 7.32 0.37 1.8e-12 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.638 rs6960778 chr7:66071597 C/T cg18876405 chr7:65276391 NA -0.44 -7.62 -0.38 2.57e-13 Aortic root size; LIHC cis rs7408868 0.831 rs7245850 chr19:15274585 A/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.87 -0.3 1.06e-8 Pulse pressure; LIHC cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg21951975 chr1:209979733 IRF6 -0.42 -6.83 -0.35 3.92e-11 Cleft lip with or without cleft palate; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg10755058 chr3:40428713 ENTPD3 0.4 6.87 0.35 3.05e-11 Renal cell carcinoma; LIHC cis rs9467773 1.000 rs1535277 chr6:26567802 G/T cg11502198 chr6:26597334 ABT1 0.46 6.71 0.34 8.01e-11 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.879 rs5758307 chr22:41750219 A/G cg03806693 chr22:41940476 POLR3H -0.48 -6.23 -0.32 1.4e-9 Vitiligo; LIHC cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg05552183 chr6:42928497 GNMT 0.49 7.06 0.36 9.43e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs8060686 0.641 rs76984161 chr16:68139423 C/A cg05110241 chr16:68378359 PRMT7 -0.6 -6.77 -0.34 5.6e-11 HDL cholesterol;Metabolic syndrome; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03732293 chr1:179335087 C1orf125 0.41 6.11 0.31 2.67e-9 Cognitive function; LIHC cis rs8141529 0.764 rs5752807 chr22:29223169 A/G cg02153584 chr22:29168773 CCDC117 0.59 9.31 0.45 1.55e-18 Lymphocyte counts; LIHC cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg00684032 chr4:1343700 KIAA1530 0.39 6.65 0.34 1.16e-10 Obesity-related traits; LIHC cis rs6688613 0.685 rs4657613 chr1:166870878 A/G ch.1.3259774R chr1:166827647 TADA1 0.4 7.21 0.36 3.58e-12 Refractive astigmatism; LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs2075371 0.966 rs2544214 chr7:133985736 G/A cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg24642844 chr7:1081250 C7orf50 -0.92 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6570726 0.935 rs12663211 chr6:145818427 G/A cg23711669 chr6:146136114 FBXO30 0.54 9.68 0.46 9.93e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.865 rs1112817 chr4:120297800 T/C cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs10792665 0.611 rs10898053 chr11:82610033 T/A cg24227371 chr11:82718527 RAB30 -0.26 -5.95 -0.31 6.73e-9 Obesity-related traits; LIHC cis rs7715806 0.500 rs58968428 chr5:75004107 A/G cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1789 0.903 rs6850422 chr4:15682437 C/T cg21123203 chr4:15471301 CC2D2A -0.43 -6.74 -0.34 6.86e-11 Blood protein levels; LIHC cis rs4892230 1 rs4892230 chr18:72155572 G/A cg26446133 chr18:72167187 CNDP2 -0.58 -9.68 -0.46 9.5e-20 Mononucleosis; LIHC cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg18404041 chr3:52824283 ITIH1 0.55 8.95 0.44 2.25e-17 Bipolar disorder; LIHC cis rs597539 0.690 rs578791 chr11:68625809 C/T cg06028808 chr11:68637592 NA 0.44 5.74 0.3 2.1e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs798766 0.903 rs811316 chr4:1689377 T/C cg21231739 chr4:1642635 FAM53A -0.38 -5.76 -0.3 1.91e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.15e-11 Prudent dietary pattern; LIHC cis rs7618501 0.633 rs9814664 chr3:50078541 C/T cg21467203 chr3:49911342 NA 0.43 7.65 0.38 2.09e-13 Intelligence (multi-trait analysis); LIHC cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg03452623 chr4:187889614 NA -0.33 -8.3 -0.41 2.51e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs1387259 0.929 rs11168484 chr12:48633589 A/C cg21466736 chr12:48725269 NA -0.7 -10.65 -0.5 4.47e-23 Obstructive sleep apnea trait (apnea hypopnea index); LIHC trans rs12478296 0.901 rs58906257 chr2:243028248 T/C cg01596870 chr19:55963115 NA -0.65 -9.1 -0.44 7.62e-18 Obesity-related traits; LIHC cis rs9341808 1.000 rs1359239 chr6:80956146 G/A cg08355045 chr6:80787529 NA 0.33 6.37 0.33 5.98e-10 Sitting height ratio; LIHC cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg20607798 chr8:58055168 NA 0.49 6.0 0.31 5.08e-9 Developmental language disorder (linguistic errors); LIHC cis rs10788264 0.544 rs911786 chr10:124017583 C/G cg04162153 chr10:124029871 BTBD16 0.43 5.86 0.3 1.11e-8 Total body bone mineral density; LIHC cis rs10256972 0.967 rs4723338 chr7:1036241 A/G cg16145915 chr7:1198662 ZFAND2A -0.28 -6.93 -0.35 2.09e-11 Longevity;Endometriosis; LIHC cis rs2637266 0.935 rs2583049 chr10:78403962 T/C cg18941641 chr10:78392320 NA 0.28 6.13 0.31 2.45e-9 Pulmonary function; LIHC cis rs6500602 0.893 rs8061742 chr16:4489436 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.31 0.32 8.81e-10 Schizophrenia; LIHC trans rs17685 0.753 rs6951808 chr7:75772413 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11792861 0.851 rs4542004 chr9:111814478 A/G cg05043794 chr9:111880884 C9orf5 -0.25 -5.82 -0.3 1.36e-8 Menarche (age at onset); LIHC cis rs2658782 0.547 rs3020054 chr11:93055556 C/T cg15737290 chr11:93063684 CCDC67 0.45 6.14 0.32 2.28e-9 Pulmonary function decline; LIHC cis rs208520 0.690 rs2797693 chr6:66868985 T/C cg07460842 chr6:66804631 NA -0.78 -8.65 -0.42 1.99e-16 Exhaled nitric oxide output; LIHC cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs6960043 0.818 rs1974620 chr7:15065467 A/G cg19272540 chr7:15055459 NA 0.23 6.54 0.33 2.29e-10 Type 2 diabetes; LIHC cis rs4654899 1.000 rs6702110 chr1:21515906 A/G cg08539965 chr1:21396338 EIF4G3 0.35 6.07 0.31 3.43e-9 Superior frontal gyrus grey matter volume; LIHC cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg05564831 chr3:52568323 NT5DC2 0.35 5.75 0.3 1.98e-8 Electroencephalogram traits; LIHC cis rs13256369 0.951 rs12679360 chr8:8566269 G/T cg18904891 chr8:8559673 CLDN23 -0.65 -10.62 -0.5 6.03e-23 Obesity-related traits; LIHC cis rs769267 0.859 rs2916076 chr19:19545990 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.54 8.14 0.4 7.23e-15 Tonsillectomy; LIHC cis rs6754311 0.731 rs748841 chr2:136558157 C/T cg15123519 chr2:136567270 LCT 0.45 9.33 0.45 1.33e-18 Mosquito bite size; LIHC cis rs7512552 0.839 rs2873669 chr1:150426224 C/T cg15654264 chr1:150340011 RPRD2 -0.7 -11.53 -0.53 3.33e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs2727020 0.521 rs11040377 chr11:49474346 T/C cg15704280 chr7:45808275 SEPT13 -0.63 -10.4 -0.49 3.51e-22 Coronary artery disease; LIHC cis rs7618501 1.000 rs34614773 chr3:49753003 T/G cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.645 rs1874969 chr11:49826700 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -19.81 -0.73 1e-58 Height; LIHC cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg06481639 chr22:41940642 POLR3H -0.61 -5.78 -0.3 1.65e-8 Vitiligo; LIHC cis rs6701037 0.566 rs1883102 chr1:175136793 T/A cg17845761 chr1:175162550 KIAA0040 0.4 6.7 0.34 8.55e-11 Alcohol dependence; LIHC cis rs1799949 0.965 rs2236762 chr17:41226675 A/T cg23758822 chr17:41437982 NA 0.91 17.07 0.68 1.13e-47 Menopause (age at onset); LIHC trans rs55986470 0.670 rs56313033 chr2:239346202 C/T cg01134436 chr17:81009848 B3GNTL1 0.84 7.22 0.36 3.37e-12 Chronotype; LIHC cis rs2153535 0.580 rs4639392 chr6:8446547 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs3020736 0.500 rs5996110 chr22:42493767 A/G cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg06845991 chr7:90032834 CLDN12 -0.43 -6.62 -0.34 1.37e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs10911232 0.507 rs4129857 chr1:183004547 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.27 0.49 9.23e-22 Hypertriglyceridemia; LIHC cis rs5769765 0.955 rs8138687 chr22:50291869 A/G cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.23e-16 Schizophrenia; LIHC cis rs798554 0.680 rs2533889 chr7:2900309 G/C cg04166393 chr7:2884313 GNA12 0.51 7.6 0.38 2.96e-13 Height; LIHC cis rs6088580 0.524 rs6087616 chr20:33263033 T/C cg08999081 chr20:33150536 PIGU -0.43 -7.26 -0.37 2.63e-12 Glomerular filtration rate (creatinine); LIHC cis rs611744 0.901 rs599357 chr8:109194160 T/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg24549020 chr5:56110836 MAP3K1 0.5 6.46 0.33 3.5e-10 Initial pursuit acceleration; LIHC trans rs11098499 0.954 rs1022145 chr4:120230979 A/G cg25214090 chr10:38739885 LOC399744 0.57 9.05 0.44 1.13e-17 Corneal astigmatism; LIHC cis rs7927592 0.956 rs10896341 chr11:68313180 G/A cg20283391 chr11:68216788 NA -0.52 -7.85 -0.39 5.44e-14 Total body bone mineral density; LIHC trans rs7618501 0.635 rs34080578 chr3:50026029 A/C cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.51 0.46 3.49e-19 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.686 rs2991987 chr1:46081422 C/G cg24296786 chr1:45957014 TESK2 0.42 6.02 0.31 4.41e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12477438 0.765 rs12468807 chr2:99691994 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.87 -0.51 7.74e-24 Chronic sinus infection; LIHC cis rs916888 0.773 rs199535 chr17:44822662 A/G cg01570182 chr17:44337453 NA 1.03 10.19 0.48 1.77e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4969178 0.965 rs12451791 chr17:76397343 G/A cg20026190 chr17:76395443 PGS1 0.46 7.29 0.37 2.11e-12 HDL cholesterol levels; LIHC cis rs10857712 0.703 rs12253520 chr10:135235321 C/A cg17796960 chr10:135278976 LOC619207 -0.35 -5.74 -0.3 2.1e-8 Systemic lupus erythematosus; LIHC cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg06634786 chr22:41940651 POLR3H -0.78 -8.54 -0.42 4.57e-16 Vitiligo; LIHC cis rs7927592 0.913 rs11228262 chr11:68274907 G/T cg16797656 chr11:68205561 LRP5 0.52 8.25 0.41 3.4e-15 Total body bone mineral density; LIHC cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg08822215 chr16:89438651 ANKRD11 -0.46 -7.19 -0.36 4.04e-12 Multiple myeloma (IgH translocation); LIHC cis rs9303401 0.614 rs3803752 chr17:56540267 C/T cg25039879 chr17:56429692 SUPT4H1 0.81 9.04 0.44 1.2e-17 Cognitive test performance; LIHC cis rs9549367 0.789 rs7999579 chr13:113879357 T/C cg00898013 chr13:113819073 PROZ -0.43 -7.43 -0.37 8.83e-13 Platelet distribution width; LIHC cis rs9378688 0.654 rs6596879 chr6:2364847 T/C cg12303981 chr6:2244766 GMDS 0.48 6.37 0.33 5.97e-10 Caudate nucleus volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17308151 chr11:8703888 RPL27A 0.46 6.14 0.32 2.25e-9 Pancreatic cancer; LIHC cis rs12744310 0.887 rs16828071 chr1:41783603 G/A cg03962019 chr1:41807865 NA 0.4 6.37 0.33 6.06e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs611744 0.967 rs684904 chr8:109199417 G/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs713477 1.000 rs713477 chr14:55904426 C/A cg13175173 chr14:55914753 NA -0.31 -7.11 -0.36 6.98e-12 Pediatric bone mineral content (femoral neck); LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg10774155 chr7:65338427 VKORC1L1 -0.43 -6.38 -0.33 5.63e-10 Calcium levels; LIHC cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg01368799 chr11:117014884 PAFAH1B2 0.41 5.78 0.3 1.67e-8 Blood protein levels; LIHC cis rs9457247 0.765 rs12212247 chr6:167413539 T/C cg07741184 chr6:167504864 NA 0.32 7.24 0.36 3.01e-12 Crohn's disease; LIHC cis rs17685 0.753 rs4573217 chr7:75733946 G/A cg04610667 chr7:75704037 NA -0.33 -5.94 -0.31 6.93e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs477692 1.000 rs548390 chr10:131417427 G/A cg19680672 chr10:131412579 MGMT -0.45 -6.85 -0.35 3.39e-11 Response to temozolomide; LIHC cis rs9911578 0.839 rs1871751 chr17:57190368 A/G cg05425664 chr17:57184151 TRIM37 -0.54 -7.8 -0.39 7.76e-14 Intelligence (multi-trait analysis); LIHC cis rs787274 1.000 rs1965335 chr9:115504483 C/T cg13803584 chr9:115635662 SNX30 0.6 6.34 0.32 7.17e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs908922 0.651 rs4240886 chr1:152530396 A/T cg20991723 chr1:152506922 NA -0.53 -8.96 -0.44 2.21e-17 Hair morphology; LIHC cis rs3204270 0.639 rs79193599 chr17:79651490 C/A cg18367735 chr17:79674897 NA 0.69 7.7 0.38 1.44e-13 Dental caries; LIHC cis rs2741335 0.876 rs2741336 chr8:27337606 C/T cg07150473 chr8:27338183 CHRNA2 -0.42 -6.03 -0.31 4.16e-9 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC trans rs1814175 0.541 rs12287397 chr11:49819799 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.93 0.35 2.12e-11 Height; LIHC cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -10.15 -0.48 2.43e-21 Platelet count; LIHC cis rs67311347 1.000 rs56992941 chr3:40472434 A/T cg13409248 chr3:40428643 ENTPD3 0.42 7.14 0.36 5.71e-12 Renal cell carcinoma; LIHC cis rs1003719 0.762 rs2835598 chr21:38466669 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.02 0.54 5.41e-28 Eye color traits; LIHC cis rs7187994 0.732 rs3764281 chr16:84767152 A/G cg07647771 chr16:84786436 USP10 -0.33 -5.84 -0.3 1.2e-8 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs11098499 0.865 rs3956464 chr4:120256764 T/C cg09307838 chr4:120376055 NA 0.7 11.05 0.51 1.72e-24 Corneal astigmatism; LIHC cis rs9733 0.596 rs7549795 chr1:150656873 G/A cg18016565 chr1:150552671 MCL1 0.58 11.41 0.53 8.67e-26 Tonsillectomy; LIHC cis rs4450131 0.898 rs3824805 chr10:126320721 C/T cg20435097 chr10:126320824 FAM53B -0.53 -9.53 -0.46 3.09e-19 White blood cell count (basophil); LIHC cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg21724239 chr8:58056113 NA 0.67 10.76 0.5 1.83e-23 Developmental language disorder (linguistic errors); LIHC cis rs9513627 0.915 rs9582298 chr13:100118707 T/C cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs3814244 0.528 rs2906854 chr12:68387346 G/A cg15249341 chr12:68405565 NA 0.33 6.78 0.34 5.29e-11 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs992157 0.710 rs6752254 chr2:219058743 C/T cg00012203 chr2:219082015 ARPC2 0.89 15.58 0.64 1.02e-41 Colorectal cancer; LIHC cis rs34172651 0.917 rs8049667 chr16:24773524 G/A cg00339695 chr16:24857497 SLC5A11 0.56 8.59 0.42 3.24e-16 Intelligence (multi-trait analysis); LIHC cis rs2243480 0.901 rs778687 chr7:65835819 G/A cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs903552 1.000 rs4965872 chr15:102004002 C/T cg19295451 chr15:102010161 PCSK6 -0.46 -6.31 -0.32 8.81e-10 Diabetic kidney disease; LIHC cis rs4819052 1.000 rs733738 chr21:46666396 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.73 -9.93 -0.47 1.34e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9341808 0.500 rs2223873 chr6:81048288 A/G cg08355045 chr6:80787529 NA 0.34 6.96 0.35 1.75e-11 Sitting height ratio; LIHC cis rs2228479 0.850 rs11076624 chr16:89855749 T/C cg19635926 chr16:89946313 TCF25 0.54 6.74 0.34 6.74e-11 Skin colour saturation; LIHC cis rs1003719 0.715 rs2051398 chr21:38550258 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.7 10.8 0.5 1.39e-23 Eye color traits; LIHC cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg05025164 chr4:1340916 KIAA1530 0.49 7.19 0.36 4.01e-12 Longevity; LIHC cis rs7116495 0.881 rs1939243 chr11:71742735 A/G cg26138937 chr11:71823887 C11orf51 0.81 7.98 0.4 2.22e-14 Severe influenza A (H1N1) infection; LIHC cis rs986417 0.748 rs2179971 chr14:61055466 T/C cg27398547 chr14:60952738 C14orf39 0.49 5.9 0.3 8.74e-9 Gut microbiota (bacterial taxa); LIHC cis rs2303759 0.670 rs45549132 chr19:49794028 G/T cg24324837 chr19:49891574 CCDC155 0.39 5.87 0.3 1.05e-8 Multiple sclerosis; LIHC cis rs3008870 1.000 rs2985821 chr1:67403787 G/A cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg12419862 chr22:24373484 LOC391322 0.69 9.87 0.47 2.25e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9916302 0.904 rs602282 chr17:37433021 C/T cg03013999 chr17:37608204 MED1 0.36 5.97 0.31 5.97e-9 Glomerular filtration rate (creatinine); LIHC cis rs79976124 0.879 rs12214239 chr6:66636059 A/G cg07460842 chr6:66804631 NA 0.65 6.79 0.34 4.98e-11 Type 2 diabetes; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09758671 chr8:99058522 RPL30 -0.5 -6.18 -0.32 1.86e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs61931739 0.500 rs6488209 chr12:34319309 A/G cg26384229 chr12:38710491 ALG10B 0.48 6.42 0.33 4.6e-10 Morning vs. evening chronotype; LIHC cis rs12950390 0.853 rs55745341 chr17:45855778 G/C cg03474202 chr17:45855739 NA -0.34 -5.98 -0.31 5.72e-9 IgG glycosylation; LIHC cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg10896456 chr17:42255109 ASB16;C17orf65 0.49 8.64 0.42 2.17e-16 Total body bone mineral density; LIHC cis rs898097 0.841 rs12453162 chr17:80859971 C/T cg15369054 chr17:80825471 TBCD 0.41 5.76 0.3 1.84e-8 Breast cancer; LIHC cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg22800045 chr5:56110881 MAP3K1 0.66 8.41 0.41 1.12e-15 Initial pursuit acceleration; LIHC cis rs1865760 0.566 rs9467672 chr6:26083904 C/T cg18357526 chr6:26021779 HIST1H4A 0.45 6.54 0.33 2.22e-10 Height; LIHC cis rs7618501 0.521 rs2352984 chr3:49948728 T/C cg05623727 chr3:50126028 RBM5 0.34 5.83 0.3 1.3e-8 Intelligence (multi-trait analysis); LIHC cis rs1506636 0.962 rs17623873 chr7:123417100 C/A cg03229431 chr7:123269106 ASB15 0.6 11.76 0.54 5e-27 Plateletcrit;Platelet count; LIHC cis rs7412746 0.611 rs4970931 chr1:150910727 G/A cg18016565 chr1:150552671 MCL1 0.5 9.51 0.46 3.62e-19 Melanoma; LIHC cis rs9527 0.615 rs10883804 chr10:104706520 G/A cg15744005 chr10:104629667 AS3MT -0.29 -5.83 -0.3 1.3e-8 Arsenic metabolism; LIHC cis rs975210 0.656 rs16954106 chr15:70357918 C/T cg01666796 chr15:70364327 TLE3 -0.59 -7.66 -0.38 1.94e-13 Height;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs11971779 0.680 rs2355785 chr7:139070983 C/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs4819052 0.851 rs1056099 chr21:46678892 G/A cg22633049 chr21:46681294 NA -0.36 -6.36 -0.33 6.34e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2851682 1.000 rs2845573 chr11:61601908 C/T cg27386326 chr11:61587980 NA -0.59 -8.81 -0.43 6.2e-17 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs4722166 0.508 rs1474348 chr7:22767908 C/G cg05472934 chr7:22766657 IL6 0.52 8.32 0.41 2.19e-15 Lung cancer; LIHC cis rs7937890 1.000 rs2970335 chr11:14325401 A/C cg22961513 chr11:14280813 SPON1 -0.44 -6.91 -0.35 2.4e-11 Mitochondrial DNA levels; LIHC cis rs2991971 0.967 rs6661321 chr1:45954599 C/G cg15605315 chr1:45957053 TESK2 0.49 6.89 0.35 2.64e-11 High light scatter reticulocyte count; LIHC cis rs798554 1.000 rs798540 chr7:2764130 G/A cg19717773 chr7:2847554 GNA12 -0.42 -6.62 -0.34 1.42e-10 Height; LIHC cis rs10883723 0.810 rs7917525 chr10:104246755 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.08 0.58 5.63e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs238295 0.843 rs238288 chr20:5591903 T/G cg24001556 chr20:5591874 RP5-1022P6.2 -0.58 -7.75 -0.39 1.08e-13 Occipital cortical area (total cortical area interaction); LIHC cis rs16828019 0.852 rs35190461 chr1:41543135 T/C cg03387723 chr1:41708464 SCMH1 -0.4 -6.53 -0.33 2.36e-10 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.655 rs7742691 chr6:86278691 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.24 0.45 2.73e-18 Response to antipsychotic treatment; LIHC trans rs2262909 0.962 rs11669110 chr19:22296485 A/G cg17074339 chr11:11642133 GALNTL4 0.47 7.32 0.37 1.83e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs7552404 1.000 rs7518038 chr1:76154430 G/A cg10523679 chr1:76189770 ACADM 0.65 9.0 0.44 1.54e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8017423 0.605 rs3742673 chr14:90735707 C/T cg14092571 chr14:90743983 NA -0.53 -8.59 -0.42 3.03e-16 Mortality in heart failure; LIHC cis rs9916302 0.904 rs12952384 chr17:37669536 T/C cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg07424592 chr7:64974309 NA 0.82 9.58 0.46 2.09e-19 Diabetic kidney disease; LIHC cis rs4665809 1.000 rs1030730 chr2:26284143 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.77 -9.42 -0.45 6.74e-19 Gut microbiome composition (summer); LIHC cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.56 0.38 3.68e-13 Bipolar disorder; LIHC cis rs968567 0.501 rs174553 chr11:61575158 A/G cg27386326 chr11:61587980 NA 0.7 14.85 0.63 7.91e-39 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs1348850 0.632 rs12467363 chr2:178502512 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.87 0.39 4.83e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg16926213 chr1:1841314 NA 0.33 6.03 0.31 4.23e-9 Body mass index; LIHC cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg06212747 chr3:49208901 KLHDC8B 0.64 8.85 0.43 4.66e-17 Menarche (age at onset); LIHC cis rs2303759 0.709 rs3760667 chr19:49814832 C/T cg22590775 chr19:49891494 CCDC155 0.47 7.49 0.38 6.12e-13 Multiple sclerosis; LIHC cis rs2884670 1.000 rs2884670 chr12:4675218 C/T cg14576962 chr12:4671597 NA -0.37 -5.94 -0.31 6.83e-9 Allergic rhinitis; LIHC cis rs9790314 0.540 rs9844862 chr3:161076188 G/A cg17135325 chr3:160939158 NMD3 0.42 6.09 0.31 3.07e-9 Morning vs. evening chronotype; LIHC cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg13047869 chr3:10149882 C3orf24 0.48 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs921968 0.541 rs593888 chr2:219427597 A/G cg02985541 chr2:219472218 PLCD4 0.42 6.94 0.35 1.94e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs801193 0.839 rs6968619 chr7:66068867 T/C cg14393609 chr7:65229607 NA -0.35 -5.78 -0.3 1.72e-8 Aortic root size; LIHC cis rs7592578 0.882 rs16832765 chr2:191468762 T/C cg27211696 chr2:191398769 TMEM194B -0.62 -7.76 -0.39 9.6e-14 Diastolic blood pressure; LIHC cis rs4319547 0.695 rs113841747 chr12:122886088 G/T cg23029597 chr12:123009494 RSRC2 0.51 7.23 0.36 3.12e-12 Body mass index; LIHC cis rs1062177 0.724 rs2964590 chr5:151118146 C/G cg00977110 chr5:151150581 G3BP1 -0.56 -6.98 -0.35 1.58e-11 Preschool internalizing problems; LIHC cis rs425277 0.538 rs169037 chr1:2095582 G/T cg03732007 chr1:2071316 PRKCZ 0.36 6.15 0.32 2.11e-9 Height; LIHC cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.95e-9 Menopause (age at onset); LIHC cis rs2050392 0.624 rs303436 chr10:30731893 G/T cg18806716 chr10:30721971 MAP3K8 -0.42 -6.11 -0.31 2.65e-9 Inflammatory bowel disease; LIHC cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg21724239 chr8:58056113 NA 0.56 7.05 0.36 9.69e-12 Developmental language disorder (linguistic errors); LIHC cis rs116095464 0.558 rs7725227 chr5:233517 G/A cg22496380 chr5:211416 CCDC127 -1.03 -10.67 -0.5 3.83e-23 Breast cancer; LIHC cis rs7617773 0.780 rs6442111 chr3:48312060 G/C cg11946769 chr3:48343235 NME6 0.87 11.2 0.52 5.12e-25 Coronary artery disease; LIHC cis rs860626 0.645 rs242963 chr10:119311371 G/C cg10846980 chr10:119306025 EMX2;EMX2OS -0.54 -8.1 -0.4 1e-14 Neuroticism; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.87 0.57 3.48e-31 Prudent dietary pattern; LIHC cis rs7572733 0.555 rs6745726 chr2:198934080 A/G cg03934865 chr2:198174659 NA 0.43 6.09 0.31 3.01e-9 Dermatomyositis; LIHC cis rs4595586 0.545 rs4768526 chr12:39402898 A/G cg26384229 chr12:38710491 ALG10B 0.52 6.19 0.32 1.71e-9 Morning vs. evening chronotype; LIHC cis rs2404602 0.647 rs4312276 chr15:77164361 T/C cg03037974 chr15:76606532 NA -0.6 -9.99 -0.48 8.76e-21 Blood metabolite levels; LIHC cis rs9814567 1.000 rs9851441 chr3:134315091 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -11.97 -0.54 8.31e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7903847 0.692 rs7900255 chr10:99157575 G/A cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.98 -23.54 -0.79 1.53e-73 Prudent dietary pattern; LIHC cis rs3749237 0.615 rs6792911 chr3:49429856 C/T cg06212747 chr3:49208901 KLHDC8B 0.45 5.87 0.3 1.02e-8 Resting heart rate; LIHC cis rs796364 0.806 rs10445792 chr2:201078821 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -7.99 -0.4 2.16e-14 Schizophrenia; LIHC cis rs4803468 1.000 rs10409485 chr19:41920765 C/T cg14132834 chr19:41945861 ATP5SL 0.44 6.49 0.33 3.05e-10 Height; LIHC cis rs8064299 0.655 rs2305214 chr17:72768970 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.68 10.63 0.5 5.51e-23 Monocyte count; LIHC cis rs9296092 0.517 rs56043172 chr6:33522363 T/G cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg08888203 chr3:10149979 C3orf24 0.62 6.93 0.35 2.15e-11 Alzheimer's disease; LIHC cis rs61990749 0.571 rs4448861 chr14:78307735 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.51 7.84 0.39 5.75e-14 Fibroblast growth factor basic levels; LIHC cis rs6952808 0.531 rs73039217 chr7:2178731 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.73 -0.47 6.67e-20 Bipolar disorder and schizophrenia; LIHC cis rs2797160 1.000 rs1418951 chr6:125996185 A/G cg05901451 chr6:126070800 HEY2 -0.41 -6.97 -0.35 1.64e-11 Endometrial cancer; LIHC cis rs798554 0.797 rs798486 chr7:2803037 A/G cg04166393 chr7:2884313 GNA12 0.43 6.0 0.31 5.06e-9 Height; LIHC cis rs1005277 0.540 rs116205409 chr10:38478970 G/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.48 -0.46 4.29e-19 Extrinsic epigenetic age acceleration; LIHC trans rs931812 1.000 rs4734494 chr8:101917721 T/C cg20993868 chr7:22813445 NA 0.29 6.34 0.32 7.36e-10 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.13 -0.31 2.37e-9 Colorectal cancer; LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs1577917 1.000 rs1995688 chr6:86632319 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23647884 chr3:120315025 NDUFB4 -0.48 -6.7 -0.34 8.73e-11 Pancreatic cancer; LIHC cis rs826838 1.000 rs11183941 chr12:38851692 G/C cg13010199 chr12:38710504 ALG10B 0.61 7.5 0.38 5.64e-13 Heart rate; LIHC cis rs1023500 0.573 rs2269524 chr22:42475703 T/G cg04733989 chr22:42467013 NAGA -0.68 -9.81 -0.47 3.45e-20 Schizophrenia; LIHC cis rs2274273 0.682 rs7151224 chr14:55517262 G/A cg01864836 chr14:55583639 NA -0.36 -6.08 -0.31 3.15e-9 Protein biomarker; LIHC cis rs7584330 0.554 rs13392410 chr2:238430273 G/A cg08992911 chr2:238395768 MLPH 0.55 6.42 0.33 4.5e-10 Prostate cancer; LIHC cis rs1461503 1.000 rs1461499 chr11:122843987 C/A cg14473756 chr11:122847823 NA -0.32 -5.75 -0.3 1.98e-8 Menarche (age at onset); LIHC cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg02290350 chr8:58132656 NA 0.4 8.54 0.42 4.47e-16 Developmental language disorder (linguistic errors); LIHC cis rs10911232 0.507 rs10797832 chr1:183044034 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 4.01e-23 Hypertriglyceridemia; LIHC cis rs10540 1.000 rs67912009 chr11:495057 G/T cg03576123 chr11:487126 PTDSS2 -1.14 -8.66 -0.42 1.86e-16 Body mass index; LIHC cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 9.22 0.45 3.2e-18 Platelet count; LIHC cis rs3008870 0.583 rs17497947 chr1:67457199 G/T cg08660285 chr1:67390436 MIER1;WDR78 -0.87 -13.34 -0.59 5.45e-33 Lymphocyte percentage of white cells; LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15854934 chr14:55518152 MAPK1IP1L 0.42 6.17 0.32 1.91e-9 Lung function (FEV1/FVC); LIHC cis rs4853012 0.793 rs6723185 chr2:74344884 T/A cg23149560 chr2:74406255 MOBKL1B 0.4 5.75 0.3 2.01e-8 Gestational age at birth (maternal effect); LIHC cis rs2153535 0.541 rs6938688 chr6:8521629 G/T cg23788917 chr6:8435910 SLC35B3 0.62 8.82 0.43 5.8e-17 Motion sickness; LIHC cis rs1552244 0.554 rs6800204 chr3:9995404 A/G cg21531657 chr3:10005747 TMEM111 0.39 5.96 0.31 6.15e-9 Alzheimer's disease; LIHC cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg09222892 chr1:25734099 RHCE -0.46 -8.43 -0.41 9.71e-16 Erythrocyte sedimentation rate; LIHC cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.83 11.29 0.52 2.48e-25 Alzheimer's disease; LIHC cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg00149659 chr3:10157352 C3orf10 -0.69 -7.16 -0.36 5.04e-12 Alzheimer's disease; LIHC cis rs5769707 0.592 rs6009783 chr22:50011001 C/G cg01652190 chr22:50026171 C22orf34 -0.33 -7.48 -0.38 6.26e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2302190 0.882 rs9903173 chr17:56607358 C/T cg05425664 chr17:57184151 TRIM37 -0.45 -5.82 -0.3 1.37e-8 Vitamin D levels; LIHC cis rs16854884 0.739 rs1898265 chr3:143776096 A/G cg06585982 chr3:143692056 C3orf58 -0.52 -6.54 -0.33 2.23e-10 Economic and political preferences (feminism/equality); LIHC cis rs655641 0.863 rs7951988 chr11:85714288 T/C cg09030501 chr11:85779252 PICALM -0.49 -5.85 -0.3 1.14e-8 Platelet count; LIHC trans rs11039798 0.920 rs11039940 chr11:48716316 C/T cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs10089 0.953 rs4835940 chr5:127406596 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.82 0.35 4.25e-11 Ileal carcinoids; LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06098346 chr12:48499667 PFKM;SENP1 -0.5 -6.68 -0.34 9.87e-11 Pancreatic cancer; LIHC cis rs151997 0.777 rs3846499 chr5:50254200 G/A cg06027927 chr5:50259733 NA 0.62 8.46 0.42 8.06e-16 Callous-unemotional behaviour; LIHC cis rs7520050 0.933 rs12045165 chr1:46256022 C/A cg03146154 chr1:46216737 IPP -0.41 -6.67 -0.34 1.01e-10 Red blood cell count;Reticulocyte count; LIHC cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg19626725 chr5:178986131 RUFY1 -0.38 -5.92 -0.31 7.7e-9 Lung cancer; LIHC cis rs9682041 0.660 rs13089074 chr3:170113481 G/A cg11886554 chr3:170076028 SKIL 0.63 5.84 0.3 1.23e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs17376456 0.877 rs10514380 chr5:93409370 C/T cg25358565 chr5:93447407 FAM172A 1.12 10.25 0.48 1.1e-21 Diabetic retinopathy; LIHC cis rs7666738 0.546 rs13105521 chr4:98734419 C/T cg05340658 chr4:99064831 C4orf37 0.48 6.35 0.32 6.73e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs11673344 0.864 rs2562587 chr19:37510259 C/T cg27390819 chr19:37464633 NA -0.49 -5.95 -0.31 6.78e-9 Obesity-related traits; LIHC cis rs477692 0.875 rs7091540 chr10:131420276 C/T cg05714579 chr10:131428358 MGMT -0.49 -8.3 -0.41 2.5e-15 Response to temozolomide; LIHC cis rs4474465 0.850 rs10899549 chr11:78255389 T/C cg27205649 chr11:78285834 NARS2 0.39 5.92 0.3 7.82e-9 Alzheimer's disease (survival time); LIHC cis rs3820068 0.734 rs72645830 chr1:15889910 A/G cg17385448 chr1:15911702 AGMAT 0.4 6.7 0.34 8.78e-11 Systolic blood pressure; LIHC cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.22 -0.36 3.41e-12 Bipolar disorder; LIHC cis rs4684776 0.676 rs1809049 chr3:11302884 C/T cg00170343 chr3:11313890 ATG7 -0.47 -6.61 -0.34 1.47e-10 Small vessel stroke; LIHC cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg06640241 chr16:89574553 SPG7 0.88 16.67 0.67 4.28e-46 Multiple myeloma (IgH translocation); LIHC cis rs57221529 0.655 rs72704791 chr5:547896 A/G cg09021430 chr5:549028 NA -0.46 -8.03 -0.4 1.61e-14 Lung disease severity in cystic fibrosis; LIHC cis rs2120019 1.000 rs34655806 chr15:75362586 T/C cg11632617 chr15:75315747 PPCDC -0.45 -6.35 -0.32 6.86e-10 Blood trace element (Zn levels); LIHC cis rs2153535 0.563 rs1737586 chr6:8535897 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.36e-16 Motion sickness; LIHC trans rs2847476 0.690 rs7929497 chr11:114192132 C/G cg16823064 chr1:19206559 ALDH4A1 -0.34 -6.3 -0.32 9.1e-10 Volumetric brain MRI; LIHC cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg00656387 chr3:40428638 ENTPD3 0.42 6.95 0.35 1.81e-11 Renal cell carcinoma; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.49e-17 Prudent dietary pattern; LIHC cis rs9649213 0.593 rs7807455 chr7:97957622 C/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.12e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs10751667 0.621 rs7396049 chr11:1001561 G/A cg10932868 chr11:921992 NA 0.34 6.43 0.33 4.32e-10 Alzheimer's disease (late onset); LIHC cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg09359103 chr1:154839909 KCNN3 -0.3 -5.72 -0.3 2.27e-8 Prostate cancer; LIHC cis rs116095464 0.558 rs10058428 chr5:235608 A/G cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.78e-52 Breast cancer; LIHC trans rs1728785 1.000 rs1645928 chr16:68590610 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.31 0.32 8.84e-10 Ulcerative colitis; LIHC cis rs6754311 0.731 rs3754686 chr2:136603276 T/C cg25344623 chr2:136566232 LCT 0.42 8.65 0.42 2.08e-16 Mosquito bite size; LIHC cis rs7903847 0.642 rs10882922 chr10:99158537 C/T cg06359132 chr10:99160096 RRP12 -0.42 -6.51 -0.33 2.73e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11229555 0.645 rs12295551 chr11:58188983 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16490440 chr1:144620428 NBPF9 0.42 6.14 0.32 2.29e-9 Longevity; LIHC trans rs4906332 1.000 rs13987 chr14:103969909 A/G cg17675199 chr6:35436792 RPL10A 0.34 6.47 0.33 3.32e-10 Coronary artery disease; LIHC cis rs2286885 0.965 rs10760440 chr9:129250831 C/T cg15282417 chr9:129245246 FAM125B 0.4 6.34 0.32 7.13e-10 Intraocular pressure; LIHC cis rs4450131 0.522 rs6597851 chr10:126413773 A/C cg20435097 chr10:126320824 FAM53B -0.63 -11.4 -0.52 9.7e-26 White blood cell count (basophil); LIHC cis rs8073060 0.519 rs8065286 chr17:33864479 A/G cg01737554 chr17:33866071 SLFN12L -0.39 -8.05 -0.4 1.35e-14 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs1355223 0.902 rs2226113 chr11:34746289 C/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg05484376 chr2:27715224 FNDC4 0.39 6.82 0.35 4.03e-11 Total body bone mineral density; LIHC cis rs7223966 1.000 rs8075521 chr17:61804954 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.96 0.35 1.72e-11 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs2797160 0.967 rs1343120 chr6:125992810 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.44 -6.33 -0.32 7.82e-10 Endometrial cancer; LIHC cis rs11190604 1.000 rs10883493 chr10:102208188 A/T cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs9929218 0.608 rs35158985 chr16:68796746 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.52 -7.96 -0.4 2.5e-14 Colorectal cancer; LIHC cis rs17401966 1.000 rs4845934 chr1:10468946 G/A cg19773385 chr1:10388646 KIF1B -0.48 -7.44 -0.37 8.34e-13 Hepatocellular carcinoma; LIHC cis rs3849570 1.000 rs3860595 chr3:81811784 A/G cg07356753 chr3:81810745 GBE1 -0.6 -8.2 -0.41 4.85e-15 Waist circumference;Body mass index; LIHC cis rs4803468 0.905 rs284662 chr19:41932275 T/C cg14132834 chr19:41945861 ATP5SL -0.46 -6.82 -0.35 4.04e-11 Height; LIHC trans rs743793 0.818 rs9607019 chr22:33580562 C/T cg20274824 chr1:36638199 MAP7D1 0.46 6.42 0.33 4.66e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs4845459 0.967 rs4112788 chr1:152551276 A/G cg20634798 chr1:152595351 LCE3A -0.31 -5.94 -0.31 6.97e-9 Psoriasis; LIHC cis rs8014204 0.544 rs2286913 chr14:75386576 G/A cg08847533 chr14:75593920 NEK9 0.47 7.61 0.38 2.61e-13 Caffeine consumption; LIHC cis rs2153535 0.580 rs6910742 chr6:8448328 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.04e-16 Motion sickness; LIHC cis rs56104184 0.578 rs7254608 chr19:49395774 G/T cg21252483 chr19:49399788 TULP2 -0.61 -9.47 -0.46 4.65e-19 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs6456156 0.586 rs10946208 chr6:167459596 C/T cg12798992 chr6:167411361 FGFR1OP 0.42 6.51 0.33 2.69e-10 Primary biliary cholangitis; LIHC cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs7618501 0.633 rs4688690 chr3:50022292 G/A cg21467203 chr3:49911342 NA -0.43 -7.74 -0.39 1.17e-13 Intelligence (multi-trait analysis); LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg10862848 chr6:42927986 GNMT -0.28 -6.66 -0.34 1.11e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs60871478 0.786 rs55899111 chr7:827843 C/G cg04727924 chr7:799746 HEATR2 0.6 8.19 0.4 5.25e-15 Cerebrospinal P-tau181p levels; LIHC cis rs3820068 0.603 rs6429767 chr1:15963334 G/A cg17385448 chr1:15911702 AGMAT 0.33 5.8 0.3 1.53e-8 Systolic blood pressure; LIHC cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg23758822 chr17:41437982 NA 0.94 17.62 0.69 6.39e-50 Menopause (age at onset); LIHC cis rs7772486 0.754 rs12199362 chr6:146118225 A/G cg05347473 chr6:146136440 FBXO30 0.39 6.18 0.32 1.86e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs763121 0.853 rs3747170 chr22:39067331 G/A cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs4906332 1.000 rs28711288 chr14:103906126 T/C cg04998671 chr14:104000505 TRMT61A -0.42 -5.9 -0.3 8.84e-9 Coronary artery disease; LIHC cis rs708547 0.624 rs1277284 chr4:57855361 T/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.69 12.41 0.56 1.92e-29 Response to bleomycin (chromatid breaks); LIHC trans rs1814175 0.817 rs28594987 chr11:50045181 C/T cg03929089 chr4:120376271 NA -0.89 -18.71 -0.71 2.82e-54 Height; LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC trans rs7618501 1.000 rs34614773 chr3:49753003 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.929 rs12699483 chr7:1975624 C/G cg14004847 chr7:1930337 MAD1L1 -0.44 -6.25 -0.32 1.24e-9 Bipolar disorder and schizophrenia; LIHC cis rs10792665 0.934 rs2105644 chr11:82656623 A/G cg24227371 chr11:82718527 RAB30 -0.29 -6.77 -0.34 5.78e-11 Obesity-related traits; LIHC cis rs2806561 0.765 rs2806557 chr1:23503372 T/A cg19743168 chr1:23544995 NA 0.36 6.0 0.31 4.94e-9 Height; LIHC cis rs2274273 0.870 rs3783650 chr14:55848972 A/C cg04306507 chr14:55594613 LGALS3 0.32 5.98 0.31 5.52e-9 Protein biomarker; LIHC trans rs11098499 0.909 rs28581362 chr4:120283548 T/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs2282032 0.527 rs8020828 chr14:90768183 C/T cg04374321 chr14:90722782 PSMC1 0.48 6.98 0.35 1.53e-11 Longevity; LIHC trans rs6598955 0.671 rs55791848 chr1:26582711 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC cis rs780096 0.565 rs13022659 chr2:27743630 C/T cg22903471 chr2:27725779 GCKR -0.53 -9.02 -0.44 1.33e-17 Total body bone mineral density; LIHC cis rs9896933 0.778 rs80112422 chr17:80827719 G/T cg20578329 chr17:80767326 TBCD -0.7 -6.71 -0.34 8.24e-11 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs8067545 0.611 rs2703812 chr17:20114803 A/G cg13482628 chr17:19912719 NA -0.42 -6.9 -0.35 2.6e-11 Schizophrenia; LIHC cis rs4660306 1.000 rs1044717 chr1:45976587 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.66 -7.98 -0.4 2.23e-14 Homocysteine levels; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg01516881 chr6:292596 DUSP22 -0.52 -6.7 -0.34 8.5e-11 Menopause (age at onset); LIHC trans rs7613875 0.580 rs2624819 chr3:50010571 G/T cg21659725 chr3:3221576 CRBN 0.55 8.29 0.41 2.61e-15 Body mass index; LIHC cis rs2762353 0.603 rs4145221 chr6:25763192 A/G cg03264133 chr6:25882463 NA 0.47 6.45 0.33 3.73e-10 Blood metabolite levels; LIHC cis rs56235845 0.964 rs11746443 chr5:176798306 G/A cg06060754 chr5:176797920 RGS14 0.72 11.35 0.52 1.43e-25 Hemoglobin concentration;Hematocrit; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg20300707 chr1:1162156 SDF4 0.62 6.39 0.33 5.53e-10 Mean platelet volume; LIHC cis rs7119038 0.818 rs6421571 chr11:118743772 T/C cg19308663 chr11:118741387 NA -0.46 -5.93 -0.31 7.53e-9 Sjögren's syndrome; LIHC cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs10028773 0.666 rs12498657 chr4:120262866 G/C cg25214090 chr10:38739885 LOC399744 0.44 7.18 0.36 4.36e-12 Educational attainment; LIHC cis rs4243830 0.850 rs932112 chr1:6591937 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.93 -12.22 -0.55 9.8e-29 Body mass index; LIHC cis rs611744 0.647 rs702808 chr8:109252554 T/C cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs4561483 0.831 rs33621 chr16:12008513 G/A cg08843971 chr16:11963173 GSPT1 -0.36 -7.12 -0.36 6.6e-12 Testicular germ cell tumor; LIHC cis rs9303401 0.659 rs62081316 chr17:56781499 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.7 0.43 1.39e-16 Cognitive test performance; LIHC cis rs3806843 0.735 rs801188 chr5:140066916 G/T cg26395211 chr5:140044315 WDR55 0.4 5.86 0.3 1.11e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7534824 0.625 rs7545402 chr1:101321076 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 6.73 0.34 7.09e-11 Refractive astigmatism; LIHC cis rs10927875 0.632 rs6699394 chr1:16145143 C/A cg21385522 chr1:16154831 NA -1.05 -17.39 -0.69 5.55e-49 Dilated cardiomyopathy; LIHC cis rs7223966 1.000 rs9901507 chr17:61765524 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.83e-12 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs4819388 0.789 rs4568033 chr21:45649778 A/G cg17383793 chr5:52405638 MOCS2 0.4 6.29 0.32 9.67e-10 Celiac disease; LIHC trans rs1814175 0.645 rs12364337 chr11:49942580 A/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg11301795 chr4:187892539 NA 0.29 7.6 0.38 2.86e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.819 rs13046807 chr21:46672286 A/G cg11663144 chr21:46675770 NA -0.32 -5.9 -0.3 8.89e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2576037 0.526 rs509647 chr18:44383675 G/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.49 -7.34 -0.37 1.61e-12 Personality dimensions; LIHC cis rs6860806 0.631 rs7736284 chr5:131588151 T/C cg24060327 chr5:131705240 SLC22A5 -0.45 -5.72 -0.3 2.38e-8 Breast cancer; LIHC cis rs6840360 0.533 rs13121190 chr4:152729072 T/G cg22705602 chr4:152727874 NA 0.39 8.18 0.4 5.8e-15 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.593 rs7134006 chr12:38596245 A/C cg26384229 chr12:38710491 ALG10B 0.9 11.57 0.53 2.38e-26 Drug-induced liver injury (flucloxacillin); LIHC cis rs1005277 0.579 rs1780146 chr10:38517874 C/A cg14646974 chr10:38645378 HSD17B7P2 -0.41 -5.75 -0.3 1.94e-8 Extrinsic epigenetic age acceleration; LIHC cis rs6088590 1.000 rs11698977 chr20:33449691 C/T cg24642439 chr20:33292090 TP53INP2 0.73 9.63 0.46 1.4e-19 Coronary artery disease; LIHC cis rs2408955 0.522 rs973398 chr12:48491048 A/G cg21466736 chr12:48725269 NA 0.63 9.14 0.44 5.64e-18 Glycated hemoglobin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00513467 chr9:21335551 KLHL9 0.43 6.25 0.32 1.25e-9 Lung function (FEV1/FVC); LIHC cis rs7107174 1.000 rs10899465 chr11:78013588 G/A cg02023728 chr11:77925099 USP35 0.5 9.38 0.45 9.31e-19 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg07424592 chr7:64974309 NA -0.8 -9.29 -0.45 1.82e-18 Diabetic kidney disease; LIHC trans rs743793 0.818 rs137387 chr22:33581050 G/A cg20274824 chr1:36638199 MAP7D1 0.46 6.42 0.33 4.66e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs11871801 0.517 rs60929812 chr17:40759448 G/A cg14558262 chr17:40713999 COASY 0.62 9.47 0.46 4.78e-19 Crohn's disease; LIHC cis rs17106184 1.000 rs3789587 chr1:51266474 C/T cg07174182 chr1:51127561 FAF1 -0.63 -7.44 -0.37 8.28e-13 Type 2 diabetes; LIHC cis rs1816752 0.905 rs9511249 chr13:24999595 G/A cg02811702 chr13:24901961 NA 0.24 5.83 0.3 1.29e-8 Obesity-related traits; LIHC cis rs875971 0.862 rs1983372 chr7:65611351 C/T cg11764359 chr7:65958608 NA -0.82 -13.72 -0.6 1.97e-34 Aortic root size; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs67478160 0.595 rs1475007 chr14:104297147 A/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.29 0.55 5.25e-29 Schizophrenia; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg23298160 chr5:137514800 BRD8;KIF20A 0.38 6.59 0.34 1.63e-10 Calcium levels; LIHC cis rs61990749 0.597 rs9788540 chr14:78132172 G/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.52 -8.67 -0.42 1.78e-16 Fibroblast growth factor basic levels; LIHC cis rs1983891 1.000 rs4714483 chr6:41528214 G/A cg20194872 chr6:41519635 FOXP4 0.43 6.84 0.35 3.74e-11 Prostate cancer; LIHC cis rs1801251 0.711 rs778368 chr2:233745333 G/C cg08000102 chr2:233561755 GIGYF2 -0.73 -10.59 -0.5 7.16e-23 Coronary artery disease; LIHC cis rs561341 0.769 rs9899093 chr17:30191954 C/G cg13647721 chr17:30228624 UTP6 0.73 6.47 0.33 3.41e-10 Hip circumference adjusted for BMI; LIHC cis rs10791323 0.572 rs10750551 chr11:133737462 G/A cg06766960 chr11:133703094 NA -0.45 -6.89 -0.35 2.67e-11 Childhood ear infection; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15792688 chr4:124693 ZNF718 0.42 6.13 0.31 2.39e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03189756 chr1:241803820 OPN3 0.4 6.09 0.31 2.98e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4888262 0.526 rs7193423 chr16:74626340 A/C cg01733217 chr16:74700730 RFWD3 0.77 14.16 0.61 3.92e-36 Testicular germ cell tumor; LIHC cis rs3762637 1.000 rs12630576 chr3:122139517 A/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC cis rs8141529 0.509 rs7287124 chr22:29239157 A/G cg02153584 chr22:29168773 CCDC117 0.5 7.44 0.37 8e-13 Lymphocyte counts; LIHC cis rs9534288 0.731 rs4942461 chr13:46551023 C/T cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs13096760 1 rs13096760 chr3:49476806 T/C cg07636037 chr3:49044803 WDR6 0.56 8.5 0.42 5.79e-16 Intelligence (multi-trait analysis); LIHC cis rs73001065 0.818 rs73004966 chr19:19716558 C/T cg03709012 chr19:19516395 GATAD2A 0.82 7.72 0.39 1.28e-13 LDL cholesterol; LIHC cis rs4332037 1.000 rs4332037 chr7:1950809 C/T cg23422044 chr7:1970798 MAD1L1 -0.58 -6.76 -0.34 5.91e-11 Bipolar disorder; LIHC cis rs2425143 1.000 rs12480408 chr20:34234800 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.89 -0.3 9.45e-9 Blood protein levels; LIHC cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.74 -13.59 -0.59 6.35e-34 Prudent dietary pattern; LIHC cis rs921968 0.542 rs630858 chr2:219409689 C/A cg02985541 chr2:219472218 PLCD4 0.41 6.72 0.34 7.42e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7617773 0.780 rs6793223 chr3:48364101 C/T cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC trans rs2681424 0.897 rs62269211 chr3:121760639 T/C cg03946530 chr15:65596423 NA -0.48 -6.2 -0.32 1.67e-9 Multiple sclerosis; LIHC cis rs2997447 0.688 rs3008431 chr1:26371281 A/G cg19633962 chr1:26362018 EXTL1 -0.75 -8.21 -0.41 4.63e-15 QRS complex (12-leadsum); LIHC cis rs7918232 0.505 rs788221 chr10:27442247 G/C cg14240646 chr10:27532245 ACBD5 0.84 6.87 0.35 2.96e-11 Breast cancer; LIHC cis rs6545883 0.794 rs12053388 chr2:61532320 G/A cg14146966 chr2:61757674 XPO1 -0.44 -7.28 -0.37 2.3e-12 Tuberculosis; LIHC cis rs7703744 0.747 rs6896553 chr5:118678700 G/T cg10911160 chr5:118691794 TNFAIP8 -0.5 -5.94 -0.31 6.86e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10411936 0.712 rs10414751 chr19:16591695 G/A cg10248733 chr19:16607483 C19orf44;CALR3 0.51 6.81 0.35 4.36e-11 White blood cell count;Multiple sclerosis; LIHC cis rs903552 0.800 rs6598479 chr15:102005913 A/C cg00659931 chr15:102010125 PCSK6 -0.49 -6.51 -0.33 2.66e-10 Diabetic kidney disease; LIHC cis rs3106136 0.649 rs4699410 chr4:95299486 T/G cg11021082 chr4:95130006 SMARCAD1 0.36 6.13 0.31 2.43e-9 Capecitabine sensitivity; LIHC cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.02 0.44 1.38e-17 Platelet count; LIHC cis rs12579753 1.000 rs11519754 chr12:82209181 A/T cg07988820 chr12:82153109 PPFIA2 -0.49 -6.06 -0.31 3.63e-9 Resting heart rate; LIHC cis rs11098499 0.644 rs17517414 chr4:120262101 G/C cg09307838 chr4:120376055 NA 0.62 9.84 0.47 2.77e-20 Corneal astigmatism; LIHC cis rs2070488 0.965 rs1870915 chr3:38494228 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.22 0.66 2.74e-44 Electrocardiographic conduction measures; LIHC cis rs4665809 0.941 rs6735145 chr2:26270302 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.68 -0.42 1.61e-16 Gut microbiome composition (summer); LIHC cis rs1997103 0.911 rs9642575 chr7:55399090 C/T cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs507080 0.733 rs657769 chr11:118571316 C/T cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg05185784 chr16:90016020 DEF8 -0.47 -6.08 -0.31 3.18e-9 Skin colour saturation; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg04860157 chr6:36842651 PPIL1 -0.44 -6.42 -0.33 4.55e-10 Triglycerides; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23715700 chr19:16188274 TPM4 0.38 6.26 0.32 1.12e-9 Cognitive function; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg14666006 chr8:27629879 CCDC25 -0.58 -6.41 -0.33 4.88e-10 Preeclampsia; LIHC cis rs8141529 0.748 rs5997412 chr22:29276747 G/A cg15103426 chr22:29168792 CCDC117 0.59 9.48 0.46 4.42e-19 Lymphocyte counts; LIHC cis rs911119 0.955 rs2067488 chr20:23594331 T/G cg16589663 chr20:23618590 CST3 0.72 7.6 0.38 2.88e-13 Chronic kidney disease; LIHC cis rs2979489 0.891 rs4537262 chr8:30306757 T/A cg26383811 chr8:30366931 RBPMS 0.73 12.35 0.56 3.06e-29 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC trans rs208520 1.000 rs12191403 chr6:66978137 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.04 0.36 1.04e-11 Exhaled nitric oxide output; LIHC cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg03452623 chr4:187889614 NA -0.36 -9.38 -0.45 9.7e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -6.09 -0.31 2.99e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs244293 0.795 rs11079150 chr17:53095061 G/C cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.45 0.37 7.84e-13 Menarche (age at onset); LIHC cis rs600806 0.888 rs3853501 chr1:109864374 G/A cg16275483 chr1:110013120 SYPL2 -0.5 -6.22 -0.32 1.44e-9 Intelligence (multi-trait analysis); LIHC cis rs2832191 0.716 rs7284006 chr21:30475186 T/A cg24692254 chr21:30365293 RNF160 0.87 16.16 0.66 4.6e-44 Dental caries; LIHC cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg25072359 chr17:41440525 NA 0.39 6.17 0.32 1.97e-9 Menopause (age at onset); LIHC cis rs2412488 0.927 rs7655975 chr4:54286484 A/G cg22241045 chr4:54363911 LNX1 -0.42 -6.87 -0.35 3.02e-11 DNA methylation (variation); LIHC cis rs34779708 0.966 rs4934730 chr10:35415555 A/G cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2067615 0.524 rs4964187 chr12:107080313 C/A cg15890332 chr12:107067104 RFX4 0.26 6.24 0.32 1.28e-9 Heart rate; LIHC cis rs2153535 0.580 rs2143355 chr6:8517856 T/A cg21535247 chr6:8435926 SLC35B3 0.63 8.29 0.41 2.68e-15 Motion sickness; LIHC cis rs6912958 0.516 rs242278 chr6:88047059 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.57 10.71 0.5 2.77e-23 Monocyte percentage of white cells; LIHC cis rs4819852 0.958 rs756653 chr22:19976845 G/A cg07821417 chr22:19972146 ARVCF 0.46 6.61 0.34 1.48e-10 Pulse pressure; LIHC cis rs7520050 0.807 rs6656279 chr1:46124088 C/G cg24296786 chr1:45957014 TESK2 -0.39 -5.88 -0.3 9.77e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1348850 0.632 rs1358328 chr2:178517532 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.91 0.39 3.62e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1801251 1.000 rs71421663 chr2:233619131 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.22 0.52 4.27e-25 Coronary artery disease; LIHC cis rs2279817 0.955 rs2270977 chr1:18023509 T/C cg21791023 chr1:18019539 ARHGEF10L 0.62 8.59 0.42 3.04e-16 Neuroticism; LIHC cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.8 0.35 4.56e-11 Gut microbiome composition (summer); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25506325 chr7:2093962 MAD1L1 0.45 6.81 0.35 4.46e-11 Bilirubin levels; LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg26354017 chr1:205819088 PM20D1 0.77 11.46 0.53 6.06e-26 Menarche (age at onset); LIHC cis rs950027 0.787 rs1153845 chr15:45724729 C/T cg26924012 chr15:45694286 SPATA5L1 -0.64 -10.38 -0.49 3.97e-22 Response to fenofibrate (adiponectin levels); LIHC cis rs10927875 0.597 rs61782184 chr1:16150976 G/A cg07117364 chr1:16154769 NA -0.39 -6.84 -0.35 3.56e-11 Dilated cardiomyopathy; LIHC cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg25894440 chr7:65020034 NA -0.55 -6.34 -0.32 7.28e-10 Diabetic kidney disease; LIHC cis rs1799949 0.860 rs8176279 chr17:41210396 A/C cg23758822 chr17:41437982 NA 0.91 16.7 0.67 3.44e-46 Menopause (age at onset); LIHC cis rs1034435 0.755 rs5767172 chr22:48892314 A/C cg05992904 chr22:48892994 FAM19A5 -0.54 -11.39 -0.52 1.03e-25 Late-onset Alzheimer's disease; LIHC cis rs12142240 0.698 rs10158236 chr1:46820896 G/T cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs2806561 0.780 rs12135629 chr1:23338899 A/G cg19743168 chr1:23544995 NA -0.38 -7.11 -0.36 7.01e-12 Height; LIHC cis rs311392 0.833 rs6473917 chr8:55090430 A/G cg11783602 chr8:55087084 NA -0.31 -6.16 -0.32 2.01e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg01339444 chr6:118972232 C6orf204 0.59 5.82 0.3 1.32e-8 Diastolic blood pressure; LIHC cis rs7777484 0.500 rs2533885 chr7:2835655 C/T cg19717773 chr7:2847554 GNA12 -0.46 -9.14 -0.44 5.52e-18 Height; LIHC cis rs7208859 0.623 rs55938328 chr17:29117010 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs748404 0.723 rs573169 chr15:43550581 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.48 0.42 6.71e-16 Lung cancer; LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg02951883 chr7:2050386 MAD1L1 -0.54 -8.12 -0.4 8.7e-15 Bipolar disorder and schizophrenia; LIHC cis rs1448094 0.511 rs61930074 chr12:86218759 G/C cg02569458 chr12:86230093 RASSF9 0.46 6.18 0.32 1.82e-9 Major depressive disorder; LIHC cis rs35110281 0.591 rs162366 chr21:44935383 C/T cg04455712 chr21:45112962 RRP1B -0.42 -7.08 -0.36 8.48e-12 Mean corpuscular volume; LIHC cis rs7264396 0.563 rs1970577 chr20:34336737 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.75 -0.43 1.02e-16 Total cholesterol levels; LIHC cis rs7208859 0.673 rs216440 chr17:28928309 A/T cg14067834 chr17:29058358 SUZ12P 0.63 6.6 0.34 1.57e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs72949976 0.864 rs13389834 chr2:214025112 G/A cg08319019 chr2:214017104 IKZF2 -0.65 -7.01 -0.35 1.25e-11 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs34375054 0.624 rs4073534 chr12:125671800 C/T cg25124228 chr12:125621409 AACS -0.43 -6.86 -0.35 3.28e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs238295 0.805 rs6076852 chr20:5544502 A/G cg24001556 chr20:5591874 RP5-1022P6.2 0.52 7.01 0.35 1.28e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs796364 0.950 rs56155997 chr2:200768491 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.69 -6.23 -0.32 1.38e-9 Schizophrenia; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.61 -12.03 -0.55 4.93e-28 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs7677751 0.806 rs6850748 chr4:55099164 T/G cg17187183 chr4:55093834 PDGFRA 0.68 8.49 0.42 6.36e-16 Corneal astigmatism; LIHC cis rs12474201 0.832 rs4952843 chr2:46957845 A/G cg06386533 chr2:46925753 SOCS5 0.69 7.88 0.39 4.56e-14 Height; LIHC cis rs1775715 0.835 rs1419169 chr10:32257204 C/G cg14930904 chr10:32216787 ARHGAP12 0.38 6.83 0.35 3.99e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs12477438 0.520 rs13035311 chr2:99717322 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 13.31 0.58 7.52e-33 Chronic sinus infection; LIHC cis rs8067354 0.574 rs2526354 chr17:57976658 A/G cg13753209 chr17:57696993 CLTC 0.69 10.11 0.48 3.49e-21 Hemoglobin concentration; LIHC cis rs1577917 1.000 rs12192992 chr6:86609915 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.58 -0.5 8.0700000000000006e-23 Response to antipsychotic treatment; LIHC trans rs9929218 1.000 rs13334294 chr16:68809278 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs9814567 1.000 rs4334685 chr3:134304335 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.0 -0.54 6.29e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs17685 0.753 rs13240967 chr7:75658197 C/T cg16684958 chr7:75615977 POR -0.51 -8.54 -0.42 4.4e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1580019 0.844 rs1901202 chr7:32503724 A/T cg07520158 chr7:32535189 LSM5;AVL9 0.5 6.74 0.34 6.57e-11 Cognitive ability; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs11758351 0.660 rs55848726 chr6:26224434 T/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs911119 0.955 rs8115417 chr20:23605223 T/A cg16589663 chr20:23618590 CST3 0.76 8.04 0.4 1.44e-14 Chronic kidney disease; LIHC cis rs561341 0.739 rs9906455 chr17:30215669 G/A cg13647721 chr17:30228624 UTP6 -0.71 -8.06 -0.4 1.3e-14 Hip circumference adjusted for BMI; LIHC cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg17554472 chr22:41940697 POLR3H -0.53 -5.82 -0.3 1.35e-8 Vitiligo; LIHC cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg26874164 chr19:58962979 ZNF324B 0.59 9.02 0.44 1.33e-17 Uric acid clearance; LIHC cis rs7937682 1.000 rs12363179 chr11:111568091 G/A cg09085632 chr11:111637200 PPP2R1B 1.09 13.26 0.58 1.12e-32 Primary sclerosing cholangitis; LIHC cis rs4975709 0.959 rs9312959 chr5:1877008 G/A cg15595755 chr5:1867978 NA 0.34 6.25 0.32 1.2e-9 Cardiovascular disease risk factors; LIHC cis rs847649 0.804 rs4729866 chr7:102685561 A/C cg18108683 chr7:102477205 FBXL13 0.45 6.88 0.35 2.85e-11 Morning vs. evening chronotype; LIHC cis rs7769051 1.000 rs9493443 chr6:133121349 C/T cg22852734 chr6:133119734 C6orf192 0.93 9.48 0.46 4.33e-19 Type 2 diabetes nephropathy; LIHC cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg21724239 chr8:58056113 NA 0.6 7.43 0.37 8.82e-13 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs12468419 chr2:99579680 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -8.62 -0.42 2.61e-16 Chronic sinus infection; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09403165 chr15:90118814 C15orf42 0.42 6.23 0.32 1.34e-9 Lung function (FEV1/FVC); LIHC cis rs16858210 0.874 rs73177525 chr3:183570286 G/C cg25686905 chr3:183603175 PARL -0.5 -9.38 -0.45 9.47e-19 Menopause (age at onset); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg21410120 chr7:540775 PDGFA 0.39 6.28 0.32 1.03e-9 Immature fraction of reticulocytes; LIHC cis rs72781680 0.716 rs72788284 chr2:24097539 A/G cg08917208 chr2:24149416 ATAD2B 0.65 6.59 0.34 1.71e-10 Lymphocyte counts; LIHC cis rs9381040 0.701 rs722442 chr6:41089681 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -6.07 -0.31 3.37e-9 Alzheimer's disease (late onset); LIHC cis rs4819052 0.819 rs34818688 chr21:46672416 C/T cg22633049 chr21:46681294 NA -0.36 -6.11 -0.31 2.75e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6762 0.748 rs1130663 chr11:837582 G/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.8 -9.95 -0.47 1.18e-20 Mean platelet volume; LIHC cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg16606324 chr3:10149918 C3orf24 0.51 5.86 0.3 1.08e-8 Alzheimer's disease; LIHC cis rs9303401 0.659 rs12940212 chr17:56674474 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.97 12.98 0.57 1.38e-31 Cognitive test performance; LIHC cis rs796364 0.806 rs11688168 chr2:200916004 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs6977660 0.714 rs2390157 chr7:19786177 G/A cg07541023 chr7:19748670 TWISTNB 0.48 7.03 0.36 1.13e-11 Thyroid stimulating hormone; LIHC trans rs7618501 1.000 rs7634902 chr3:49762662 G/T cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs3796352 1.000 rs13069006 chr3:52973305 G/C cg04865290 chr3:52927548 TMEM110 -0.51 -5.89 -0.3 9.01e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7408868 0.831 rs11672004 chr19:15277282 T/A cg09752223 chr19:15281200 NOTCH3 -0.36 -6.29 -0.32 9.6e-10 Pulse pressure; LIHC cis rs7810240 1.000 rs56333034 chr7:150093330 G/A cg10018233 chr7:150070692 REPIN1 -0.4 -6.19 -0.32 1.77e-9 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; LIHC cis rs4730268 1.000 rs4730268 chr7:107443386 C/T cg18560240 chr7:107437656 SLC26A3 -0.49 -5.85 -0.3 1.17e-8 IgG glycosylation; LIHC cis rs2439831 0.850 rs12441984 chr15:44126285 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.73 0.34 7.11e-11 Lung cancer in ever smokers; LIHC cis rs8072100 0.512 rs9303533 chr17:45386540 A/G cg25173405 chr17:45401733 C17orf57 -0.44 -6.0 -0.31 4.89e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs955333 0.543 rs6557365 chr6:154924457 A/G cg01304710 chr4:3766151 NA 0.26 6.16 0.32 2e-9 Diabetic kidney disease; LIHC cis rs860295 0.756 rs7546258 chr1:155698645 T/A cg02153340 chr1:155202674 NA -0.35 -6.35 -0.32 6.94e-10 Body mass index; LIHC cis rs908922 0.676 rs568661 chr1:152519787 C/A cg20991723 chr1:152506922 NA 0.54 9.0 0.44 1.57e-17 Hair morphology; LIHC cis rs1707322 0.682 rs10890334 chr1:46100378 A/T cg03146154 chr1:46216737 IPP 0.56 9.52 0.46 3.31e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg13271783 chr10:134563150 INPP5A -0.56 -6.5 -0.33 2.79e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7131987 0.650 rs7957339 chr12:29456495 T/C cg14222432 chr12:29376421 FAR2 0.35 6.77 0.34 5.62e-11 QT interval; LIHC cis rs72781680 0.898 rs55761273 chr2:23957849 A/G cg08917208 chr2:24149416 ATAD2B 0.83 7.63 0.38 2.42e-13 Lymphocyte counts; LIHC cis rs9914988 0.943 rs67327562 chr17:27108828 G/A cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6967414 0.786 rs6953825 chr7:6755624 A/C cg00387323 chr7:6746715 ZNF12 0.68 7.19 0.36 4.16e-12 Hematocrit;Hemoglobin concentration; LIHC cis rs9560113 0.573 rs9560130 chr13:112229460 G/A cg10483660 chr13:112241077 NA 0.24 6.01 0.31 4.67e-9 Menarche (age at onset); LIHC trans rs61931739 0.500 rs12367292 chr12:33998075 T/C cg26384229 chr12:38710491 ALG10B 0.49 6.79 0.34 5.01e-11 Morning vs. evening chronotype; LIHC cis rs10751667 0.666 rs10902247 chr11:953686 G/A cg10932868 chr11:921992 NA 0.39 7.3 0.37 2.09e-12 Alzheimer's disease (late onset); LIHC cis rs875971 0.862 rs6460307 chr7:66060871 A/G cg18252515 chr7:66147081 NA -0.46 -6.9 -0.35 2.55e-11 Aortic root size; LIHC cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg06640241 chr16:89574553 SPG7 0.79 14.84 0.63 8.41e-39 Multiple myeloma (IgH translocation); LIHC cis rs2074193 0.951 rs215345 chr12:47733033 C/T cg02516419 chr12:47771422 NA -0.42 -5.82 -0.3 1.38e-8 Migraine with aura; LIHC cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg08923669 chr16:420230 MRPL28 -0.43 -5.9 -0.3 8.9e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs35306767 0.761 rs1871621 chr10:1049596 C/T cg26597838 chr10:835615 NA 0.9 8.69 0.43 1.54e-16 Eosinophil percentage of granulocytes; LIHC cis rs9814567 0.752 rs4955547 chr3:134334975 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.57 -9.09 -0.44 8.15e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2153535 0.541 rs6938688 chr6:8521629 G/T cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.22e-26 Motion sickness; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg07677032 chr17:61819896 STRADA 0.45 6.55 0.33 2.14e-10 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg00815214 chr21:47717953 NA 0.36 5.81 0.3 1.45e-8 Testicular germ cell tumor; LIHC cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg23758822 chr17:41437982 NA 0.91 16.72 0.67 2.64e-46 Menopause (age at onset); LIHC cis rs600806 0.815 rs4970730 chr1:109979526 T/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.82 -0.3 1.32e-8 Intelligence (multi-trait analysis); LIHC cis rs9399135 1.000 rs1014021 chr6:135334600 C/T cg24558204 chr6:135376177 HBS1L -0.4 -6.68 -0.34 9.72e-11 Red blood cell count; LIHC cis rs3892630 0.824 rs35700505 chr19:33325006 C/T cg22980127 chr19:33182716 NUDT19 1.0 11.81 0.54 3.17e-27 Red blood cell traits; LIHC cis rs3020736 0.500 rs7364293 chr22:42506370 C/T cg15557168 chr22:42548783 NA 0.44 7.0 0.35 1.32e-11 Autism spectrum disorder or schizophrenia; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg17175376 chr5:145562478 LARS -0.4 -6.15 -0.32 2.17e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6933660 0.745 rs9397405 chr6:151736084 G/T cg14262678 chr6:151773367 RMND1;C6orf211 0.54 8.02 0.4 1.69e-14 Menarche (age at onset); LIHC cis rs10876993 0.928 rs1678530 chr12:58054076 A/C cg18357645 chr12:58087776 OS9 0.52 8.5 0.42 5.89e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs911119 0.909 rs111360484 chr20:23618984 G/C cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05360402 chr5:110848191 STARD4 0.38 6.24 0.32 1.28e-9 Cognitive function; LIHC cis rs67478160 0.619 rs12886363 chr14:104273786 T/C cg08213375 chr14:104286397 PPP1R13B 0.64 12.12 0.55 2.24e-28 Schizophrenia; LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg14671364 chr1:107599128 PRMT6 0.53 7.93 0.39 3.05e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4629710 0.645 rs34601891 chr6:131551238 C/T cg12606694 chr6:131520996 AKAP7 0.64 7.39 0.37 1.14e-12 Multiple myeloma (IgH translocation); LIHC cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg03806693 chr22:41940476 POLR3H -0.99 -10.54 -0.5 1.11e-22 Vitiligo; LIHC cis rs10791097 0.694 rs876641 chr11:130752040 A/C cg14779329 chr11:130786720 SNX19 0.41 6.24 0.32 1.26e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs988712 0.705 rs10767654 chr11:27640223 T/G cg18117895 chr11:27722066 BDNF -0.44 -5.85 -0.3 1.14e-8 Obesity; LIHC cis rs738322 0.600 rs5995542 chr22:38558141 C/T cg25457927 chr22:38595422 NA -0.36 -8.56 -0.42 3.75e-16 Cutaneous nevi; LIHC cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.86 7.63 0.38 2.32e-13 Platelet count; LIHC cis rs2839627 0.561 rs4148970 chr21:44313293 A/G cg18192155 chr21:44258298 NA 0.44 7.01 0.35 1.27e-11 Information processing speed; LIHC cis rs2839627 0.561 rs9977774 chr21:44342476 G/C cg18192155 chr21:44258298 NA 0.42 5.77 0.3 1.8e-8 Information processing speed; LIHC cis rs4684776 0.867 rs921226 chr3:11324794 A/G cg00170343 chr3:11313890 ATG7 0.48 6.68 0.34 9.54e-11 Small vessel stroke; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg23260799 chr11:451101 PTDSS2 -0.41 -6.16 -0.32 1.99e-9 Urinary tract infection frequency; LIHC cis rs6088580 0.660 rs6059893 chr20:33105897 T/G cg08999081 chr20:33150536 PIGU 0.67 13.45 0.59 2.07e-33 Glomerular filtration rate (creatinine); LIHC cis rs6918586 0.658 rs198813 chr6:26128226 C/T cg18357526 chr6:26021779 HIST1H4A -0.57 -8.65 -0.42 2.01e-16 Schizophrenia; LIHC cis rs7615952 0.599 rs2333408 chr3:125732098 G/A cg05084668 chr3:125655381 ALG1L -0.43 -7.08 -0.36 8.17e-12 Blood pressure (smoking interaction); LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg22963979 chr7:1858916 MAD1L1 -0.44 -7.21 -0.36 3.69e-12 Bipolar disorder and schizophrenia; LIHC cis rs11792861 0.816 rs11791845 chr9:111683898 G/A cg05043794 chr9:111880884 C9orf5 -0.3 -7.06 -0.36 9.11e-12 Menarche (age at onset); LIHC cis rs738321 0.725 rs5756926 chr22:38542613 T/C cg25457927 chr22:38595422 NA -0.35 -7.84 -0.39 5.64e-14 Breast cancer; LIHC cis rs875971 0.755 rs10228885 chr7:65780529 C/G cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs875971 0.628 rs6974355 chr7:65841981 A/G cg14393609 chr7:65229607 NA 0.39 5.76 0.3 1.92e-8 Aortic root size; LIHC cis rs875971 0.862 rs801206 chr7:66021966 C/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg24209194 chr3:40518798 ZNF619 0.63 9.62 0.46 1.51e-19 Renal cell carcinoma; LIHC cis rs17213078 0.602 rs4851926 chr2:106742660 A/G cg15412446 chr2:106886593 NA 0.39 5.72 0.3 2.32e-8 Facial morphology (factor 23); LIHC trans rs2540949 0.538 rs2540970 chr2:65255099 C/T cg02773337 chr10:3171970 PFKP -0.36 -6.28 -0.32 1.01e-9 Atrial fibrillation; LIHC trans rs2681424 1.000 rs12495209 chr3:121757803 A/C cg03946530 chr15:65596423 NA -0.48 -6.14 -0.32 2.35e-9 Multiple sclerosis; LIHC trans rs2832077 0.943 rs11700746 chr21:30189207 T/C cg14791747 chr16:20752902 THUMPD1 0.47 6.29 0.32 9.64e-10 Cognitive test performance; LIHC cis rs1256061 0.624 rs1256046 chr14:64729356 A/C cg23250157 chr14:64679961 SYNE2 0.4 6.03 0.31 4.25e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs769267 0.501 rs2965187 chr19:19522970 T/A cg21559469 chr19:19431446 KIAA0892;SF4 0.62 7.29 0.37 2.22e-12 Tonsillectomy; LIHC cis rs919433 0.647 rs1979239 chr2:198498316 T/G cg03934865 chr2:198174659 NA 0.47 7.02 0.35 1.2e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1801251 0.778 rs709933 chr2:233733144 G/A cg25237894 chr2:233734115 C2orf82 -0.59 -11.89 -0.54 1.55e-27 Coronary artery disease; LIHC cis rs9325144 0.600 rs10785615 chr12:38733627 G/C cg26384229 chr12:38710491 ALG10B 0.56 7.82 0.39 6.52e-14 Morning vs. evening chronotype; LIHC cis rs9911578 1.000 rs4398153 chr17:56968181 T/C cg05425664 chr17:57184151 TRIM37 0.61 9.03 0.44 1.31e-17 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06109949 chr2:178937838 PDE11A 0.47 7.34 0.37 1.56e-12 Pancreatic cancer; LIHC cis rs1552244 0.882 rs3732967 chr3:10015437 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs896854 0.714 rs572547 chr8:95966286 A/G cg23172400 chr8:95962367 TP53INP1 0.38 7.64 0.38 2.27e-13 Type 2 diabetes; LIHC trans rs2243480 1.000 rs6964245 chr7:65718717 G/A cg10756647 chr7:56101905 PSPH -1.03 -12.48 -0.56 1.05e-29 Diabetic kidney disease; LIHC cis rs56235845 0.694 rs36102285 chr5:176774018 C/T cg06060754 chr5:176797920 RGS14 0.47 6.72 0.34 7.41e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs1448094 0.512 rs7960130 chr12:86243191 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs9818758 0.607 rs67831908 chr3:49313513 T/G cg06212747 chr3:49208901 KLHDC8B -0.68 -5.95 -0.31 6.67e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.85 -0.3 1.16e-8 Total body bone mineral density; LIHC cis rs9921222 0.565 rs10903014 chr16:377623 A/G cg26944245 chr16:421049 TMEM8A;MRPL28 0.52 11.05 0.51 1.75e-24 Bone mineral density (spine);Bone mineral density; LIHC cis rs11628318 0.614 rs72635192 chr14:103128646 C/T cg23461800 chr14:103021989 NA 0.45 6.31 0.32 8.6e-10 Platelet count; LIHC cis rs6942756 0.955 rs55638303 chr7:128885770 C/T cg02491457 chr7:128862824 NA -0.72 -11.37 -0.52 1.31e-25 White matter hyperintensity burden; LIHC cis rs9993613 0.935 rs6844500 chr4:73442681 G/A cg15102770 chr4:73434591 ADAMTS3 -0.39 -6.19 -0.32 1.69e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs17539620 0.624 rs62432740 chr6:154836054 C/T cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs2067615 0.599 rs1579808 chr12:107239947 A/G cg15890332 chr12:107067104 RFX4 -0.25 -5.79 -0.3 1.61e-8 Heart rate; LIHC trans rs66573146 0.561 rs67245546 chr4:6947164 T/C cg07817883 chr1:32538562 TMEM39B 1.2 10.14 0.48 2.69e-21 Granulocyte percentage of myeloid white cells; LIHC cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -6.16 -0.32 2.04e-9 Bipolar disorder and schizophrenia; LIHC cis rs6430585 0.591 rs1374330 chr2:136420908 A/C cg07169764 chr2:136633963 MCM6 0.63 7.72 0.39 1.28e-13 Corneal structure; LIHC cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg12463550 chr7:65579703 CRCP 0.67 7.08 0.36 7.98e-12 Diabetic kidney disease; LIHC cis rs6426558 0.502 rs2813965 chr1:227445733 A/G cg10327440 chr1:227177885 CDC42BPA 0.4 6.19 0.32 1.76e-9 Neutrophil percentage of white cells; LIHC cis rs6061231 0.597 rs624313 chr20:60927412 G/A cg03945807 chr20:60948434 NA -0.38 -6.9 -0.35 2.52e-11 Colorectal cancer; LIHC cis rs12464559 0.522 rs7583148 chr2:152620986 C/T cg01189475 chr2:152685088 ARL5A 0.65 7.99 0.4 2.02e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7116495 0.786 rs678193 chr11:71770273 A/C cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg10802521 chr3:52805072 NEK4 -0.42 -6.94 -0.35 1.92e-11 Bipolar disorder; LIHC cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg21782813 chr7:2030301 MAD1L1 0.41 6.93 0.35 2.11e-11 Bipolar disorder and schizophrenia; LIHC cis rs9911578 0.967 rs11656413 chr17:57082013 A/C cg05425664 chr17:57184151 TRIM37 0.59 8.88 0.43 3.78e-17 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.611 rs2280627 chr1:150935872 A/G cg18016565 chr1:150552671 MCL1 0.49 9.35 0.45 1.17e-18 Melanoma; LIHC cis rs12477438 0.798 rs1580068 chr2:99649969 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.41 -0.53 8.75e-26 Chronic sinus infection; LIHC cis rs9649213 0.586 rs55648546 chr7:97960800 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.57 -10.21 -0.48 1.54e-21 Prostate cancer (SNP x SNP interaction); LIHC cis rs4319547 0.695 rs10773167 chr12:122934001 C/T cg05707623 chr12:122985044 ZCCHC8 -0.58 -7.6 -0.38 2.83e-13 Body mass index; LIHC cis rs4665809 1.000 rs2289022 chr2:26350136 G/T cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs5769765 1.000 rs4824112 chr22:50284345 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.82 -10.13 -0.48 2.99e-21 Schizophrenia; LIHC cis rs10489202 0.632 rs149912 chr1:167957803 A/T cg24449463 chr1:168025552 DCAF6 -0.62 -9.65 -0.46 1.25e-19 Schizophrenia; LIHC cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg02951883 chr7:2050386 MAD1L1 -0.51 -7.74 -0.39 1.1e-13 Bipolar disorder and schizophrenia; LIHC cis rs10751667 0.621 rs11246345 chr11:934924 T/C cg06064525 chr11:970664 AP2A2 -0.55 -14.76 -0.62 1.8e-38 Alzheimer's disease (late onset); LIHC cis rs637571 0.676 rs634534 chr11:65665256 A/G cg26695010 chr11:65641043 EFEMP2 0.44 6.04 0.31 4e-9 Eosinophil percentage of white cells; LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg04234412 chr22:24373322 LOC391322 -0.66 -9.77 -0.47 4.71e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10791097 0.694 rs4264159 chr11:130755784 G/T cg14779329 chr11:130786720 SNX19 0.42 6.39 0.33 5.31e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2066819 0.818 rs773652 chr12:56674766 G/A cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Psoriasis vulgaris; LIHC cis rs17711722 0.583 rs10085415 chr7:65093568 T/A cg26939375 chr7:64535504 NA -0.4 -5.89 -0.3 9.09e-9 Calcium levels; LIHC trans rs877282 1.000 rs2004479 chr10:770854 G/A cg22713356 chr15:30763199 NA 1.26 11.29 0.52 2.46e-25 Uric acid levels; LIHC cis rs6430585 0.583 rs60253740 chr2:136571852 G/T cg15123519 chr2:136567270 LCT -0.38 -6.06 -0.31 3.64e-9 Corneal structure; LIHC cis rs2073499 0.872 rs58051625 chr3:50278717 G/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.67 7.02 0.35 1.24e-11 Schizophrenia; LIHC cis rs11630290 0.639 rs925248 chr15:64167543 G/A cg12036633 chr15:63758958 NA 0.57 5.96 0.31 6.42e-9 Iris characteristics; LIHC cis rs6952808 0.825 rs34922657 chr7:1938655 C/T cg21782813 chr7:2030301 MAD1L1 0.43 6.97 0.35 1.6e-11 Bipolar disorder and schizophrenia; LIHC trans rs7721647 0.810 rs6864520 chr5:90799016 A/G cg10859192 chr12:54071672 ATP5G2 -0.41 -6.07 -0.31 3.43e-9 Breast cancer; LIHC cis rs7216064 0.906 rs8074644 chr17:65878217 G/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs244293 0.760 rs8069447 chr17:53008873 A/C cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.44 -0.37 8e-13 Menarche (age at onset); LIHC cis rs2153535 0.580 rs9406167 chr6:8502852 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.83 0.54 2.74e-27 Motion sickness; LIHC trans rs1814175 0.645 rs10839456 chr11:49964093 C/T cg03929089 chr4:120376271 NA -0.84 -15.88 -0.65 6.5e-43 Height; LIHC cis rs6088580 0.634 rs6120644 chr20:33023810 G/A cg08999081 chr20:33150536 PIGU 0.67 13.28 0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs7618501 0.699 rs3733135 chr3:49939587 G/A cg24110177 chr3:50126178 RBM5 -0.51 -7.88 -0.39 4.27e-14 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.967 rs7146640 chr14:90720114 C/T cg04374321 chr14:90722782 PSMC1 -0.73 -13.87 -0.6 5.32e-35 Mortality in heart failure; LIHC cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg13126279 chr21:47581558 C21orf56 -0.47 -7.68 -0.38 1.68e-13 Testicular germ cell tumor; LIHC cis rs10276381 0.786 rs10281102 chr7:28243473 A/G cg23620719 chr7:28220237 JAZF1 0.6 7.63 0.38 2.37e-13 Crohn's disease; LIHC cis rs6545883 0.791 rs2600665 chr2:61405795 G/T cg15711740 chr2:61764176 XPO1 -0.42 -5.86 -0.3 1.06e-8 Tuberculosis; LIHC cis rs2257205 0.667 rs8075108 chr17:56657248 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.86 0.39 5.22e-14 Pancreatic cancer; LIHC cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg13877915 chr19:58951672 ZNF132 0.63 10.74 0.5 2.24e-23 Uric acid clearance; LIHC trans rs4714291 0.832 rs6936016 chr6:40097013 A/G cg02267698 chr19:7991119 CTXN1 -0.4 -6.75 -0.34 6.34e-11 Strep throat; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21433329 chr20:49574938 DPM1;MOCS3 -0.42 -6.15 -0.32 2.13e-9 Pancreatic cancer; LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg13397359 chr6:42928475 GNMT 0.65 9.36 0.45 1.1e-18 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7833986 0.501 rs2719245 chr8:56894359 G/C cg23139584 chr8:56987506 RPS20;SNORD54 0.87 8.76 0.43 9.08e-17 Height; LIHC cis rs4970988 0.556 rs6681426 chr1:150586971 G/A cg18016565 chr1:150552671 MCL1 -0.66 -13.08 -0.58 5.4e-32 Urate levels; LIHC cis rs17685 0.753 rs6976532 chr7:75681094 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.68 -0.38 1.67e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg09904177 chr6:26538194 HMGN4 0.57 11.21 0.52 4.9e-25 Intelligence (multi-trait analysis); LIHC cis rs826838 0.967 rs1719856 chr12:39127201 C/T cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.4e-8 Heart rate; LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg01339444 chr6:118972232 C6orf204 0.59 5.82 0.3 1.32e-8 Diastolic blood pressure; LIHC trans rs2243480 1.000 rs1267820 chr7:66050295 C/G cg07424592 chr7:64974309 NA 0.78 8.94 0.44 2.44e-17 Diabetic kidney disease; LIHC trans rs2243480 0.708 rs35310401 chr7:65390359 A/G cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs6973256 0.569 rs13246174 chr7:133395004 C/T cg10665199 chr7:133106180 EXOC4 0.35 6.03 0.31 4.27e-9 Intelligence (multi-trait analysis); LIHC cis rs10791097 0.748 rs4937580 chr11:130734270 T/C cg12179176 chr11:130786555 SNX19 0.8 13.08 0.58 5.67e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06446895 chr17:79829189 ARHGDIA 0.58 7.54 0.38 4.24e-13 Lung function (FEV1/FVC); LIHC cis rs2549003 0.966 rs10065633 chr5:131816716 T/C cg21138405 chr5:131827807 IRF1 0.37 9.6 0.46 1.71e-19 Asthma (sex interaction); LIHC cis rs9549328 0.718 rs7139939 chr13:113634409 G/A cg08528486 chr13:113648767 MCF2L -0.39 -6.35 -0.32 6.69e-10 Systolic blood pressure; LIHC cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg15691649 chr6:25882328 NA -0.54 -7.75 -0.39 1.07e-13 Blood metabolite levels; LIHC cis rs7772486 0.754 rs9399561 chr6:145955687 C/G cg05347473 chr6:146136440 FBXO30 0.36 5.86 0.3 1.1e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs11969893 0.850 rs9390697 chr6:101294431 G/A cg12253828 chr6:101329408 ASCC3 1.06 13.37 0.59 4.41e-33 Economic and political preferences (immigration/crime); LIHC cis rs4076764 0.958 rs12022261 chr1:163398422 A/G cg24596788 chr1:163392923 NA -0.25 -7.77 -0.39 9.52e-14 Motion sickness; LIHC cis rs11792861 0.890 rs57387569 chr9:111920392 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.15 0.4 6.9e-15 Menarche (age at onset); LIHC cis rs6912958 0.781 rs9450739 chr6:88268271 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.7 -0.38 1.44e-13 Monocyte percentage of white cells; LIHC cis rs926392 0.965 rs6129168 chr20:37689360 T/C cg16355469 chr20:37678765 NA 0.36 5.77 0.3 1.76e-8 Dialysis-related mortality; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC cis rs10504073 0.647 rs59064792 chr8:50018337 A/C cg00325661 chr8:49890786 NA 0.32 7.23 0.36 3.19e-12 Blood metabolite ratios; LIHC cis rs1461503 0.966 rs1461502 chr11:122844927 C/G cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs1552244 0.882 rs2030564 chr3:10039044 A/G cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs12497850 0.931 rs7431710 chr3:48935583 G/A cg06212747 chr3:49208901 KLHDC8B 0.57 7.39 0.37 1.11e-12 Parkinson's disease; LIHC cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.47 0.46 4.67e-19 Bipolar disorder; LIHC cis rs9513627 0.920 rs7320057 chr13:100155586 G/A cg25919922 chr13:100150906 NA 0.78 7.14 0.36 5.66e-12 Obesity-related traits; LIHC cis rs763121 0.962 rs5757135 chr22:38952573 C/T cg06022373 chr22:39101656 GTPBP1 0.63 12.03 0.55 4.99e-28 Menopause (age at onset); LIHC cis rs2292096 0.929 rs16847224 chr1:200764858 G/A cg11814564 chr1:200748674 CAMSAP1L1 -0.46 -6.16 -0.32 2.03e-9 Epilepsy; LIHC cis rs11166927 0.967 rs12680346 chr8:140814379 C/T cg16909799 chr8:140841666 TRAPPC9 0.45 7.22 0.36 3.41e-12 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs10751667 0.925 rs7115336 chr11:988101 C/G ch.11.42038R chr11:967971 AP2A2 0.59 10.91 0.51 5.7e-24 Alzheimer's disease (late onset); LIHC cis rs17253792 0.545 rs12894613 chr14:56016221 T/C cg01858014 chr14:56050164 KTN1 -0.62 -5.89 -0.3 9.46e-9 Putamen volume; LIHC cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.47e-18 Bipolar disorder; LIHC cis rs1395 0.922 rs11693052 chr2:27484620 A/G cg23587288 chr2:27483067 SLC30A3 -0.3 -5.8 -0.3 1.53e-8 Blood metabolite levels; LIHC cis rs11098499 0.954 rs13145352 chr4:120409963 C/T cg09307838 chr4:120376055 NA -0.81 -12.39 -0.56 2.33e-29 Corneal astigmatism; LIHC cis rs3008870 0.958 rs12131222 chr1:67438535 A/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC trans rs9929218 0.581 rs4783676 chr16:68801077 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.79 15.87 0.65 6.9e-43 Colorectal cancer; LIHC cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg11502198 chr6:26597334 ABT1 0.65 10.24 0.48 1.21e-21 Intelligence (multi-trait analysis); LIHC cis rs1355223 0.902 rs865070 chr11:34742497 A/G cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.43 -0.33 4.18e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.5 -7.51 -0.38 5.23e-13 Gut microbiome composition (summer); LIHC cis rs17826219 0.561 rs11655876 chr17:29017150 G/A cg13385521 chr17:29058706 SUZ12P 0.69 7.3 0.37 2.04e-12 Body mass index; LIHC cis rs7487075 0.780 rs10785624 chr12:46766787 C/T cg11331445 chr12:47219877 SLC38A4 0.29 5.93 0.31 7.49e-9 Itch intensity from mosquito bite; LIHC cis rs11190604 0.943 rs59481707 chr10:102317603 G/A cg07080220 chr10:102295463 HIF1AN 0.49 6.42 0.33 4.54e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs929354 1.000 rs1182414 chr7:157058363 G/A cg17757837 chr7:157058334 UBE3C -0.84 -14.07 -0.61 8.7e-36 Body mass index; LIHC cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs12474201 0.928 rs13025984 chr2:46938789 T/C cg06386533 chr2:46925753 SOCS5 0.75 8.35 0.41 1.71e-15 Height; LIHC cis rs2404602 0.647 rs12439141 chr15:77095423 T/C cg03037974 chr15:76606532 NA -0.6 -10.01 -0.48 7.38e-21 Blood metabolite levels; LIHC cis rs757081 0.667 rs12577388 chr11:17101155 C/T cg15432903 chr11:17409602 KCNJ11 -0.42 -5.84 -0.3 1.24e-8 Systolic blood pressure; LIHC cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg06481639 chr22:41940642 POLR3H 0.71 7.21 0.36 3.53e-12 Vitiligo; LIHC cis rs12477438 0.748 rs4851185 chr2:99666497 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs733592 0.507 rs10875739 chr12:48480919 C/T cg21466736 chr12:48725269 NA -0.35 -6.07 -0.31 3.38e-9 Plateletcrit; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg17462381 chr3:132441365 NCRNA00119;NPHP3 -0.47 -6.21 -0.32 1.55e-9 Bilirubin levels; LIHC trans rs875971 1.000 rs10257427 chr7:65743208 T/C cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.16e-10 Aortic root size; LIHC cis rs7927771 0.965 rs4752881 chr11:47898535 A/G cg20135002 chr11:47629003 NA -0.52 -8.88 -0.43 3.73e-17 Subjective well-being; LIHC cis rs2257205 0.667 rs9909635 chr17:56752159 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.79 0.39 8.05e-14 Pancreatic cancer; LIHC cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg13409248 chr3:40428643 ENTPD3 0.4 6.55 0.33 2.15e-10 Renal cell carcinoma; LIHC cis rs12477438 0.798 rs1349778 chr2:99645011 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.36 -0.64 7.55e-41 Chronic sinus infection; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg10252516 chr19:56671462 ZNF444 0.44 6.51 0.33 2.76e-10 Bilirubin levels; LIHC cis rs6951245 0.935 rs11763765 chr7:1060510 C/T cg24642844 chr7:1081250 C7orf50 -0.89 -8.94 -0.44 2.52e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10426930 0.607 rs2613768 chr19:5074637 G/A cg18473234 chr19:5097819 KDM4B -0.62 -7.49 -0.38 6.07e-13 Monocyte percentage of white cells; LIHC cis rs2439831 0.850 rs3097773 chr15:43893072 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.52 -7.01 -0.35 1.28e-11 Lung cancer in ever smokers; LIHC cis rs7959452 0.590 rs11177643 chr12:69785712 T/G cg22834771 chr12:69754056 YEATS4 -0.52 -9.23 -0.45 2.82e-18 Blood protein levels; LIHC cis rs2777491 0.872 rs11267024 chr15:41576241 C/T cg18705301 chr15:41695430 NDUFAF1 -0.51 -7.24 -0.36 3.03e-12 Ulcerative colitis; LIHC cis rs17106184 0.579 rs12074850 chr1:51248316 A/G cg07174182 chr1:51127561 FAF1 -0.6 -7.03 -0.36 1.1e-11 Type 2 diabetes; LIHC cis rs9649213 0.593 rs2240349 chr7:97984663 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs7903847 0.642 rs10882909 chr10:99137998 G/C cg06359132 chr10:99160096 RRP12 -0.42 -6.43 -0.33 4.2e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7772486 0.558 rs2142978 chr6:146012061 T/C cg23711669 chr6:146136114 FBXO30 -0.64 -9.78 -0.47 4.5e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7107174 1.000 rs2511166 chr11:77964331 T/C cg02023728 chr11:77925099 USP35 0.44 8.44 0.42 8.87e-16 Testicular germ cell tumor; LIHC cis rs35883536 1.000 rs1577504 chr1:101123913 A/T cg14515779 chr1:101123966 NA -0.69 -13.94 -0.6 2.76e-35 Monocyte count; LIHC cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg11764359 chr7:65958608 NA 0.68 9.31 0.45 1.58e-18 Calcium levels; LIHC cis rs2050392 0.624 rs2489842 chr10:30721991 T/C cg18806716 chr10:30721971 MAP3K8 -0.41 -5.78 -0.3 1.64e-8 Inflammatory bowel disease; LIHC cis rs77861329 1.000 rs893056 chr3:52109564 G/A cg08692210 chr3:52188851 WDR51A 0.84 7.32 0.37 1.82e-12 Macrophage inflammatory protein 1b levels; LIHC cis rs11098499 0.820 rs13122709 chr4:120555356 T/A cg09307838 chr4:120376055 NA 0.71 10.66 0.5 4.29e-23 Corneal astigmatism; LIHC cis rs10792665 0.512 rs7104905 chr11:82610139 A/G cg24227371 chr11:82718527 RAB30 -0.28 -6.59 -0.34 1.69e-10 Obesity-related traits; LIHC cis rs2016586 0.802 rs5755925 chr22:36114994 A/G cg26342177 chr22:36113512 APOL5 -0.38 -6.49 -0.33 3.01e-10 Body mass index; LIHC trans rs11165623 0.564 rs6673207 chr1:96999259 C/G cg10631902 chr5:14652156 NA -0.28 -6.52 -0.33 2.45e-10 Hip circumference;Waist circumference; LIHC cis rs11628318 0.515 rs10144272 chr14:103086289 T/G cg12046867 chr14:103022105 NA -0.37 -5.72 -0.3 2.28e-8 Platelet count; LIHC cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg22168489 chr12:122356033 WDR66 0.46 6.53 0.33 2.33e-10 Mean corpuscular volume; LIHC cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg17971929 chr21:40555470 PSMG1 -0.41 -6.18 -0.32 1.79e-9 Menarche (age at onset); LIHC cis rs6840360 0.571 rs12647566 chr4:152482525 C/T cg22705602 chr4:152727874 NA -0.34 -6.66 -0.34 1.08e-10 Intelligence (multi-trait analysis); LIHC cis rs2976388 1.000 rs2976398 chr8:143764879 G/C cg06565975 chr8:143823917 SLURP1 -0.31 -5.86 -0.3 1.06e-8 Urinary tract infection frequency; LIHC cis rs10791097 0.935 rs4601795 chr11:130729430 T/C cg12179176 chr11:130786555 SNX19 0.63 9.98 0.47 9.42e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs921968 0.591 rs3731877 chr2:219602499 G/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.9e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg12016809 chr21:47604291 C21orf56 -0.42 -5.99 -0.31 5.22e-9 Testicular germ cell tumor; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg25405998 chr7:65216604 CCT6P1 0.44 6.53 0.33 2.41e-10 Calcium levels; LIHC cis rs11958404 0.860 rs11135023 chr5:157420082 G/T cg05962755 chr5:157440814 NA 0.83 10.79 0.5 1.44e-23 IgG glycosylation; LIHC cis rs58235267 0.591 rs2162014 chr2:63345507 C/A cg17519650 chr2:63277830 OTX1 0.51 7.62 0.38 2.59e-13 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs3096299 0.967 rs16965692 chr16:89471482 C/T cg06640241 chr16:89574553 SPG7 0.65 10.44 0.49 2.49e-22 Multiple myeloma (IgH translocation); LIHC cis rs2573652 0.963 rs2573649 chr15:100514040 C/G cg09918751 chr15:100517450 ADAMTS17 -0.82 -14.73 -0.62 2.28e-38 Height; LIHC cis rs3784262 0.904 rs3784263 chr15:58253062 C/T cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.57 -0.33 1.93e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs644799 0.965 rs2950522 chr11:95524719 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.7 10.18 0.48 2.02e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10463316 0.817 rs10476770 chr5:150777720 G/C cg03212797 chr5:150827313 SLC36A1 -0.41 -6.19 -0.32 1.76e-9 Metabolite levels (Pyroglutamine); LIHC cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.73 -0.39 1.2e-13 Bipolar disorder; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg14257396 chr1:107603778 NA -0.35 -5.76 -0.3 1.9e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6831352 0.918 rs29001214 chr4:100051733 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs6545883 0.831 rs2592356 chr2:61810428 G/C cg14146966 chr2:61757674 XPO1 0.48 8.3 0.41 2.47e-15 Tuberculosis; LIHC cis rs2243480 1.000 rs2707831 chr7:66062511 G/A cg12463550 chr7:65579703 CRCP 0.66 6.86 0.35 3.28e-11 Diabetic kidney disease; LIHC cis rs2832191 0.716 rs2297252 chr21:30377104 G/A cg08807101 chr21:30365312 RNF160 0.79 12.26 0.55 7.09e-29 Dental caries; LIHC cis rs17401966 0.894 rs12141201 chr1:10454714 G/A cg15208524 chr1:10270712 KIF1B 0.4 5.83 0.3 1.27e-8 Hepatocellular carcinoma; LIHC cis rs965469 1.000 rs2236122 chr20:3305240 C/T cg25506879 chr20:3388711 C20orf194 -0.55 -6.63 -0.34 1.3e-10 IFN-related cytopenia; LIHC cis rs8017423 0.935 rs11624890 chr14:90738165 T/A cg04374321 chr14:90722782 PSMC1 -0.77 -14.69 -0.62 3.22e-38 Mortality in heart failure; LIHC cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg02290350 chr8:58132656 NA 0.45 8.65 0.42 2.09e-16 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg00800038 chr16:89945340 TCF25 -0.67 -10.47 -0.49 1.92e-22 Skin colour saturation; LIHC cis rs7582720 0.943 rs72936866 chr2:203787120 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs77633900 0.772 rs157768 chr15:76833779 C/T cg21673338 chr15:77095150 SCAPER -0.53 -6.09 -0.31 3.11e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs116975820 0.648 rs11181363 chr12:42566282 T/C cg01256987 chr12:42539512 GXYLT1 -0.55 -6.06 -0.31 3.56e-9 PR interval in Tripanosoma cruzi seropositivity; LIHC cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg04772025 chr11:68637568 NA 0.46 6.22 0.32 1.44e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9297145 0.678 rs62473048 chr7:98775511 T/C cg05967295 chr7:98741636 SMURF1 0.71 10.31 0.49 7.24e-22 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs7647973 0.925 rs4955421 chr3:49218888 G/A cg07636037 chr3:49044803 WDR6 0.51 6.49 0.33 3.08e-10 Menarche (age at onset); LIHC cis rs12701220 0.901 rs12701710 chr7:1090396 A/G cg00990874 chr7:1149470 C7orf50 0.66 9.43 0.45 6.59e-19 Bronchopulmonary dysplasia; LIHC cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.22 0.32 1.43e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9378688 1.000 rs56196406 chr6:2219565 T/C cg12303981 chr6:2244766 GMDS -0.5 -6.31 -0.32 8.61e-10 Caudate nucleus volume; LIHC cis rs9921222 0.597 rs7193109 chr16:413523 T/G cg26944245 chr16:421049 TMEM8A;MRPL28 0.45 8.27 0.41 3.11e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs10744422 1.000 rs4993320 chr12:123338092 T/C cg18912006 chr12:123335444 HIP1R -0.64 -7.67 -0.38 1.78e-13 Schizophrenia; LIHC cis rs3784262 0.631 rs6493980 chr15:58352290 A/G cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.73 -0.3 2.25e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg14159672 chr1:205819179 PM20D1 0.82 11.44 0.53 7.07e-26 Menarche (age at onset); LIHC cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.47 0.46 4.81e-19 Electroencephalogram traits; LIHC cis rs4727027 0.704 rs1123992 chr7:148907201 C/G cg23583168 chr7:148888333 NA -0.55 -8.52 -0.42 5.18e-16 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7953249 0.807 rs7970695 chr12:121423376 G/A cg02403541 chr12:121454288 C12orf43 -0.37 -6.3 -0.32 9.4e-10 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs734999 0.588 rs6689711 chr1:2531467 T/C cg18854424 chr1:2615690 NA -0.33 -7.25 -0.36 2.82e-12 Ulcerative colitis; LIHC cis rs896854 0.517 rs2013597 chr8:95951807 G/A cg13393036 chr8:95962371 TP53INP1 -0.37 -8.02 -0.4 1.74e-14 Type 2 diabetes; LIHC cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg26939375 chr7:64535504 NA -0.47 -7.11 -0.36 6.97e-12 Aortic root size; LIHC cis rs4820539 1.000 rs3827316 chr22:23468538 T/C cg21100191 chr22:23484243 RTDR1 0.9 16.31 0.66 1.26e-44 Bone mineral density; LIHC cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg27170947 chr2:26402098 FAM59B -0.66 -8.24 -0.41 3.72e-15 Gut microbiome composition (summer); LIHC cis rs12048904 0.505 rs4517368 chr1:101255052 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.57 -8.64 -0.42 2.18e-16 Multiple sclerosis; LIHC cis rs10876993 0.715 rs2169987 chr12:58012111 G/A cg15848620 chr12:58087721 OS9 0.5 6.43 0.33 4.2e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs897984 0.683 rs8046001 chr16:30833321 C/T cg00531865 chr16:30841666 NA -0.41 -6.62 -0.34 1.42e-10 Dementia with Lewy bodies; LIHC cis rs1256061 0.603 rs1256041 chr14:64738029 A/G cg23250157 chr14:64679961 SYNE2 0.4 6.03 0.31 4.25e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs17102423 0.654 rs8008095 chr14:65525794 A/G cg16583315 chr14:65563665 MAX -0.36 -6.83 -0.35 3.84e-11 Obesity-related traits; LIHC cis rs2239547 0.618 rs1573815 chr3:52870132 A/G cg11645453 chr3:52864694 ITIH4 -0.34 -8.75 -0.43 9.93e-17 Schizophrenia; LIHC cis rs4843747 0.636 rs4075597 chr16:88107590 C/A cg00677901 chr16:88017247 BANP 0.52 7.87 0.39 4.62e-14 Menopause (age at onset); LIHC cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg23758822 chr17:41437982 NA 0.94 17.99 0.7 2.25e-51 Menopause (age at onset); LIHC trans rs17685 0.753 rs7804598 chr7:75702578 C/T cg19862616 chr7:65841803 NCRNA00174 0.91 18.79 0.71 1.31e-54 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs11722228 0.549 rs73212863 chr4:10104173 C/T cg26043149 chr18:55253948 FECH 0.98 13.75 0.6 1.46e-34 Gout;Urate levels;Serum uric acid levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03041730 chr4:903314 GAK 0.47 6.75 0.34 6.35e-11 Longevity; LIHC cis rs600806 0.888 rs3853501 chr1:109864374 G/A cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.31 -0.37 1.89e-12 Intelligence (multi-trait analysis); LIHC cis rs12478296 0.792 rs6738361 chr2:243014257 C/T cg18898632 chr2:242989856 NA -0.69 -8.68 -0.42 1.63e-16 Obesity-related traits; LIHC cis rs9325144 0.555 rs1825806 chr12:38692547 G/A cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.42e-14 Morning vs. evening chronotype; LIHC cis rs10849893 0.538 rs7961855 chr12:121829943 C/T cg01154721 chr12:121881891 KDM2B -0.4 -6.52 -0.33 2.57e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs11779988 0.545 rs427168 chr8:17784829 G/A cg01800426 chr8:17659068 MTUS1 -0.42 -5.92 -0.3 7.96e-9 Breast cancer; LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg23782820 chr8:58130467 NA 0.33 5.95 0.31 6.66e-9 Developmental language disorder (linguistic errors); LIHC cis rs8017423 0.967 rs8021881 chr14:90722276 T/C cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.18e-41 Mortality in heart failure; LIHC cis rs10845606 0.505 rs10845604 chr12:12832734 A/G cg09462578 chr12:12878428 APOLD1 0.44 6.66 0.34 1.08e-10 Systemic lupus erythematosus; LIHC cis rs2303759 0.918 rs9749416 chr19:49885005 G/A cg22590775 chr19:49891494 CCDC155 0.46 7.52 0.38 4.84e-13 Multiple sclerosis; LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs12744310 1.000 rs35812095 chr1:41766074 T/C cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.6e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs79149102 0.579 rs74023908 chr15:75310710 T/C cg16226627 chr15:75307476 SCAMP5 0.52 9.34 0.45 1.29e-18 Lung cancer; LIHC cis rs11688816 0.904 rs360791 chr2:62917256 G/A cg17519650 chr2:63277830 OTX1 -0.47 -7.2 -0.36 3.88e-12 Body mass index; LIHC cis rs1538970 0.816 rs11211123 chr1:45957609 G/A cg24296786 chr1:45957014 TESK2 -0.51 -7.52 -0.38 4.86e-13 Platelet count; LIHC cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 0.48 6.83 0.35 3.83e-11 Schizophrenia; LIHC cis rs9910055 0.529 rs228767 chr17:42188311 C/G cg19774624 chr17:42201019 HDAC5 0.51 6.32 0.32 8.05e-10 Total body bone mineral density; LIHC cis rs3762637 0.943 rs78429050 chr3:122252428 T/C cg24169773 chr3:122142474 KPNA1 -0.45 -8.92 -0.43 2.94e-17 LDL cholesterol levels; LIHC cis rs5769707 0.872 rs5770604 chr22:50030672 G/A cg01652190 chr22:50026171 C22orf34 -0.3 -6.85 -0.35 3.48e-11 Monocyte count;Monocyte percentage of white cells; LIHC trans rs75804782 0.641 rs112066551 chr2:239362486 G/A cg01134436 chr17:81009848 B3GNTL1 0.86 7.22 0.36 3.31e-12 Morning vs. evening chronotype;Chronotype; LIHC trans rs3780486 0.757 rs10813949 chr9:33123464 G/A cg20290983 chr6:43655470 MRPS18A 1.15 29.4 0.85 1.23e-95 IgG glycosylation; LIHC cis rs7520050 0.966 rs785491 chr1:46583418 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.8 0.3 1.5e-8 Red blood cell count;Reticulocyte count; LIHC cis rs796364 0.760 rs2202922 chr2:200882610 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 7.5 0.38 5.46e-13 Schizophrenia; LIHC cis rs1198430 0.562 rs10799795 chr1:23773998 C/A cg13183780 chr1:23809682 ASAP3 -0.34 -6.02 -0.31 4.61e-9 Total cholesterol levels; LIHC cis rs7729447 0.776 rs58529247 chr5:32693889 C/T cg16267343 chr5:32710456 NPR3 0.47 5.78 0.3 1.71e-8 Blood pressure; LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg21724239 chr8:58056113 NA 0.57 7.54 0.38 4.37e-13 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs11605275 1.000 rs11605275 chr11:20031865 C/T cg14835545 chr11:20032148 NAV2 -0.81 -7.38 -0.37 1.18e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2832077 0.943 rs2832106 chr21:30191767 A/G cg14791747 chr16:20752902 THUMPD1 0.47 6.29 0.32 9.64e-10 Cognitive test performance; LIHC cis rs7264396 0.747 rs2425158 chr20:34419664 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -10.36 -0.49 4.83e-22 Total cholesterol levels; LIHC cis rs904251 0.523 rs2797799 chr6:37483620 T/G cg01843034 chr6:37503916 NA -0.47 -8.12 -0.4 8.59e-15 Cognitive performance; LIHC cis rs1055129 0.560 rs2608880 chr17:73938957 C/T cg14829360 chr17:73884958 NA -0.38 -6.41 -0.33 4.94e-10 White matter hyperintensity burden; LIHC cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg11644478 chr21:40555479 PSMG1 -0.59 -6.98 -0.35 1.51e-11 Cognitive function; LIHC cis rs11190604 0.767 rs11190534 chr10:102190930 G/A cg07080220 chr10:102295463 HIF1AN 0.47 6.93 0.35 2.08e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs523522 0.962 rs7488320 chr12:120981630 G/T cg27279351 chr12:120934652 DYNLL1 0.67 11.93 0.54 1.11e-27 High light scatter reticulocyte count; LIHC cis rs17608059 0.504 rs11656981 chr17:13978777 A/G cg27005118 chr17:13972210 COX10 -0.42 -7.89 -0.39 4.15e-14 Temperament; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs34375054 0.573 rs12831151 chr12:125656263 C/T cg25124228 chr12:125621409 AACS -0.43 -6.67 -0.34 1.05e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs35110281 0.782 rs2329442 chr21:45041790 T/C cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.42e-23 Mean corpuscular volume; LIHC cis rs1555399 0.935 rs7144333 chr14:67984105 C/T cg16224230 chr14:67978224 TMEM229B -0.25 -5.95 -0.31 6.81e-9 Parkinson's disease; LIHC cis rs9322817 0.691 rs56075147 chr6:105337494 T/A cg02098413 chr6:105308735 HACE1 0.39 7.48 0.38 6.25e-13 Thyroid stimulating hormone; LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg20295408 chr7:1910781 MAD1L1 -0.4 -5.77 -0.3 1.78e-8 Bipolar disorder and schizophrenia; LIHC cis rs9868809 0.542 rs9873726 chr3:48712367 C/T cg07636037 chr3:49044803 WDR6 -0.57 -6.96 -0.35 1.71e-11 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs4132509 0.649 rs12140040 chr1:243871922 G/A cg21452805 chr1:244014465 NA 0.46 5.83 0.3 1.32e-8 RR interval (heart rate); LIHC cis rs9486719 0.948 rs12203657 chr6:96883285 G/A cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs875971 0.545 rs1547529 chr7:65723846 T/C cg11764359 chr7:65958608 NA 0.57 8.02 0.4 1.73e-14 Aortic root size; LIHC cis rs7647973 0.961 rs11130187 chr3:49307872 T/C cg07636037 chr3:49044803 WDR6 0.51 6.5 0.33 2.78e-10 Menarche (age at onset); LIHC cis rs875971 0.723 rs28391294 chr7:65654315 T/C cg18876405 chr7:65276391 NA -0.36 -6.37 -0.33 5.93e-10 Aortic root size; LIHC cis rs2832191 0.692 rs2245517 chr21:30357968 C/T cg08807101 chr21:30365312 RNF160 0.79 11.94 0.54 1.09e-27 Dental caries; LIHC cis rs1707322 1.000 rs785484 chr1:46574015 T/C cg03146154 chr1:46216737 IPP -0.46 -7.28 -0.37 2.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.817 rs55949560 chr8:58167603 T/C cg02290350 chr8:58132656 NA 0.39 8.4 0.41 1.23e-15 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg10755058 chr3:40428713 ENTPD3 0.36 6.09 0.31 2.95e-9 Renal cell carcinoma; LIHC cis rs9916302 0.653 rs4239223 chr17:37717004 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -11.72 -0.54 7.03e-27 Glomerular filtration rate (creatinine); LIHC cis rs7264396 0.790 rs6060541 chr20:34248066 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.45 -0.53 6.66e-26 Total cholesterol levels; LIHC cis rs7618501 0.574 rs6765484 chr3:50041313 C/T cg24110177 chr3:50126178 RBM5 0.48 7.81 0.39 7.22e-14 Intelligence (multi-trait analysis); LIHC cis rs3796619 1.000 rs11939380 chr4:1086871 C/T cg27284194 chr4:1044797 NA -0.62 -10.45 -0.49 2.21e-22 Recombination rate (males); LIHC cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg05368731 chr17:41323189 NBR1 0.72 12.37 0.56 2.77e-29 Menopause (age at onset); LIHC trans rs208520 0.690 rs1304672 chr6:66847973 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.71 7.6 0.38 2.96e-13 Exhaled nitric oxide output; LIHC cis rs6430585 0.759 rs12467770 chr2:136536095 G/A cg07169764 chr2:136633963 MCM6 1.15 16.19 0.66 3.6e-44 Corneal structure; LIHC cis rs62458065 0.513 rs787220 chr7:32581139 C/G cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -7.13 -0.36 5.88e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs7647973 0.626 rs1491985 chr3:49739507 G/C cg03060546 chr3:49711283 APEH 0.58 6.72 0.34 7.66e-11 Menarche (age at onset); LIHC cis rs6430585 1.000 rs73958618 chr2:136500475 A/G cg07169764 chr2:136633963 MCM6 1.05 14.54 0.62 1.3e-37 Corneal structure; LIHC cis rs7116495 1.000 rs4944232 chr11:71642258 A/G cg26138937 chr11:71823887 C11orf51 0.83 8.25 0.41 3.52e-15 Severe influenza A (H1N1) infection; LIHC cis rs78456975 1.000 rs6744743 chr2:1558161 C/T cg01028140 chr2:1542097 TPO 0.52 6.55 0.33 2.14e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.74 -13.93 -0.6 2.98e-35 Prudent dietary pattern; LIHC cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg11645453 chr3:52864694 ITIH4 0.22 5.9 0.3 8.59e-9 Bipolar disorder; LIHC trans rs9747201 1.000 rs9303023 chr17:80175920 C/T cg07393940 chr7:158741817 NA 0.54 6.25 0.32 1.21e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4906332 0.966 rs12894275 chr14:103901424 A/G cg19000871 chr14:103996768 TRMT61A 0.44 7.39 0.37 1.13e-12 Coronary artery disease; LIHC cis rs4718428 0.705 rs28648401 chr7:66367132 T/C cg12165864 chr7:66369176 NA -0.46 -6.76 -0.34 5.84e-11 Corneal structure; LIHC cis rs2576037 0.526 rs509647 chr18:44383675 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.65 10.15 0.48 2.56e-21 Personality dimensions; LIHC cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg04267008 chr7:1944627 MAD1L1 -0.57 -8.66 -0.42 1.85e-16 Bipolar disorder and schizophrenia; LIHC cis rs763014 0.966 rs15564 chr16:677854 G/T cg04709771 chr16:646395 RAB40C 0.45 8.27 0.41 3.01e-15 Height; LIHC cis rs3823572 0.542 rs2346267 chr7:133639554 T/C cg03336402 chr7:133662267 EXOC4 0.46 5.75 0.3 2e-8 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13492289 chr10:51027379 PARG 0.42 6.5 0.33 2.91e-10 Longevity; LIHC cis rs546131 0.642 rs12272777 chr11:34850902 A/G cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.55 -0.33 2.17e-10 Lung disease severity in cystic fibrosis; LIHC cis rs7224737 1.000 rs7214921 chr17:40294025 T/C cg02450064 chr17:40260053 DHX58 -0.3 -6.15 -0.32 2.17e-9 Fibrinogen levels; LIHC cis rs937213 0.573 rs12592831 chr15:40302441 G/A cg20255370 chr15:40268687 EIF2AK4 -0.37 -6.17 -0.32 1.88e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC trans rs208520 0.560 rs2351880 chr6:66863707 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.03 -0.4 1.59e-14 Exhaled nitric oxide output; LIHC cis rs10752881 1.000 rs6697739 chr1:182983333 A/C ch.1.3577855R chr1:183094577 LAMC1 0.58 10.09 0.48 4.09e-21 Colorectal cancer; LIHC cis rs2073300 0.609 rs3746737 chr20:23424638 C/T cg12062639 chr20:23401060 NAPB 1.02 13.17 0.58 2.63e-32 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7666738 1.000 rs35066600 chr4:98991066 C/A cg05340658 chr4:99064831 C4orf37 0.68 11.56 0.53 2.64e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs9393777 0.513 rs7759969 chr6:26663096 T/A cg12826209 chr6:26865740 GUSBL1 0.55 5.8 0.3 1.48e-8 Intelligence (multi-trait analysis); LIHC cis rs986417 0.818 rs761557 chr14:61077484 C/T cg27398547 chr14:60952738 C14orf39 -0.59 -6.2 -0.32 1.66e-9 Gut microbiota (bacterial taxa); LIHC trans rs2159537 0.526 rs12940578 chr17:12366311 C/T cg20708305 chr3:9744919 CPNE9 0.39 6.07 0.31 3.44e-9 Systolic blood pressure change trajectories; LIHC cis rs7249142 0.549 rs741706 chr19:19281672 C/T cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.86 -0.35 3.24e-11 IgG glycosylation; LIHC cis rs7584330 0.554 rs74001384 chr2:238424530 T/C cg08992911 chr2:238395768 MLPH 0.48 5.93 0.31 7.32e-9 Prostate cancer; LIHC cis rs11031096 0.711 rs10835694 chr11:4178757 G/C cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.46e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs11039798 0.588 rs113800184 chr11:48756855 G/A cg03929089 chr4:120376271 NA 0.53 6.13 0.31 2.43e-9 Axial length; LIHC cis rs27434 0.607 rs695965 chr5:96148366 C/T cg16492584 chr5:96139282 ERAP1 -0.33 -6.13 -0.31 2.41e-9 Ankylosing spondylitis; LIHC cis rs57502260 0.704 rs12286536 chr11:68290234 C/G cg16797656 chr11:68205561 LRP5 0.46 5.81 0.3 1.45e-8 Total body bone mineral density (age 45-60); LIHC cis rs1801251 0.778 rs2250665 chr2:233752639 A/T cg25237894 chr2:233734115 C2orf82 -0.57 -10.96 -0.51 3.6e-24 Coronary artery disease; LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg16132339 chr22:24313637 DDTL;DDT 0.71 13.07 0.58 6.06e-32 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11098499 0.691 rs9996494 chr4:120238880 C/A cg09307838 chr4:120376055 NA 0.72 11.27 0.52 2.89e-25 Corneal astigmatism; LIHC cis rs2236918 0.710 rs851781 chr1:242034868 C/T cg17736920 chr1:242011382 EXO1 0.41 6.07 0.31 3.48e-9 Menopause (age at onset); LIHC cis rs2281845 0.965 rs3738262 chr1:201083343 A/G cg01987224 chr1:201084466 NA -0.32 -5.98 -0.31 5.76e-9 Permanent tooth development; LIHC cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg10802521 chr3:52805072 NEK4 -0.4 -6.44 -0.33 4.11e-10 Bipolar disorder; LIHC cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg02951883 chr7:2050386 MAD1L1 -0.54 -7.89 -0.39 4.08e-14 Bipolar disorder and schizophrenia; LIHC cis rs9359856 0.510 rs6454775 chr6:90465000 A/T cg13799429 chr6:90582589 CASP8AP2 0.79 9.02 0.44 1.39e-17 Bipolar disorder; LIHC cis rs763121 0.853 rs6001204 chr22:39100239 T/C cg06022373 chr22:39101656 GTPBP1 0.74 14.71 0.62 2.82e-38 Menopause (age at onset); LIHC trans rs6489882 0.703 rs10850093 chr12:113360468 C/T cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg18538332 chr22:24372958 LOC391322 -0.58 -8.01 -0.4 1.86e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7223966 1.000 rs8078862 chr17:61854068 C/T cg05941027 chr17:61774174 LIMD2 0.35 7.39 0.37 1.13e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs3796352 0.527 rs11715498 chr3:52943551 G/C cg04865290 chr3:52927548 TMEM110 -0.49 -6.45 -0.33 3.89e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7659604 0.540 rs28672860 chr4:122705051 G/A cg19671926 chr4:122722719 EXOSC9 0.56 8.63 0.42 2.3e-16 Type 2 diabetes; LIHC cis rs9611565 0.592 rs5758427 chr22:42099688 A/G cg06634786 chr22:41940651 POLR3H 0.6 6.48 0.33 3.17e-10 Vitiligo; LIHC cis rs7552404 0.691 rs1770890 chr1:76401117 A/G cg10523679 chr1:76189770 ACADM -0.57 -6.96 -0.35 1.78e-11 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs1005277 0.557 rs1854563 chr10:38434961 G/A cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs12188164 0.561 rs2251843 chr5:457955 C/T cg26076054 chr5:421317 AHRR -0.27 -6.05 -0.31 3.81e-9 Cystic fibrosis severity; LIHC cis rs4561483 0.583 rs1019814 chr16:11940764 T/C cg08843971 chr16:11963173 GSPT1 0.37 7.09 0.36 7.9e-12 Testicular germ cell tumor; LIHC cis rs2549003 0.966 rs10213701 chr5:131824064 T/A cg21138405 chr5:131827807 IRF1 0.35 8.97 0.44 2.02e-17 Asthma (sex interaction); LIHC cis rs1843834 0.539 rs2047135 chr2:225427302 G/C cg12698349 chr2:225449008 CUL3 0.68 10.37 0.49 4.2e-22 IgE levels in asthmatics (D.p. specific); LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.72 10.49 0.49 1.61e-22 Lymphocyte counts; LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg21782813 chr7:2030301 MAD1L1 0.55 10.18 0.48 1.92e-21 Bipolar disorder and schizophrenia; LIHC cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg12436631 chr1:155007014 DCST1;DCST2 -0.62 -13.36 -0.59 4.76e-33 Schizophrenia; LIHC cis rs7618501 0.699 rs9821675 chr3:49902544 A/G cg21467203 chr3:49911342 NA -0.51 -8.85 -0.43 4.63e-17 Intelligence (multi-trait analysis); LIHC cis rs3749237 0.595 rs4855864 chr3:49521974 C/T cg02487422 chr3:49467188 NICN1 0.4 6.25 0.32 1.26e-9 Resting heart rate; LIHC cis rs3820068 0.656 rs72645829 chr1:15889748 A/G cg17385448 chr1:15911702 AGMAT 0.41 6.8 0.35 4.65e-11 Systolic blood pressure; LIHC cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.38 0.45 9.63e-19 Bipolar disorder; LIHC cis rs8180040 0.691 rs12489211 chr3:47221451 T/A cg02527881 chr3:46936655 PTH1R -0.32 -6.32 -0.32 8.4e-10 Colorectal cancer; LIHC cis rs1865760 0.551 rs9461230 chr6:26019240 G/C cg17691542 chr6:26056736 HIST1H1C 0.44 6.24 0.32 1.27e-9 Height; LIHC cis rs4654899 0.758 rs6690574 chr1:21504279 G/A cg08539965 chr1:21396338 EIF4G3 0.32 5.75 0.3 1.94e-8 Superior frontal gyrus grey matter volume; LIHC cis rs35146811 0.844 rs10281368 chr7:99655897 A/G cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.41 5.98 0.31 5.71e-9 Coronary artery disease; LIHC cis rs7772486 0.790 rs9497425 chr6:146234197 G/A cg05347473 chr6:146136440 FBXO30 -0.35 -5.76 -0.3 1.88e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs3820068 0.705 rs1800616 chr1:15832229 G/A cg17385448 chr1:15911702 AGMAT 0.38 6.51 0.33 2.6200000000000003e-10 Systolic blood pressure; LIHC cis rs4746818 0.793 rs2805913 chr10:70858062 A/G cg11621586 chr10:70884670 VPS26A 0.55 8.02 0.4 1.69e-14 Left atrial antero-posterior diameter; LIHC cis rs4819052 0.851 rs2236444 chr21:46678226 T/C cg22633049 chr21:46681294 NA -0.35 -5.97 -0.31 5.8e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs950169 0.922 rs4842946 chr15:84942331 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 8.65 0.42 2.04e-16 Schizophrenia; LIHC cis rs4819052 0.851 rs8126930 chr21:46671715 A/G cg22633049 chr21:46681294 NA -0.34 -6.01 -0.31 4.68e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs75908454 1.000 rs16887979 chr6:169801808 G/A cg19338460 chr6:170058176 WDR27 -0.83 -7.52 -0.38 4.91e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs10911232 0.507 rs4652765 chr1:182994147 C/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs6089829 0.855 rs4809459 chr20:61661345 C/T cg08564027 chr20:61660810 NA 0.4 7.67 0.38 1.84e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs13161895 1.000 rs27012 chr5:179402211 A/C cg06664874 chr5:179499304 RNF130 0.55 6.84 0.35 3.66e-11 LDL cholesterol; LIHC cis rs114532231 0.661 rs34339158 chr2:86498574 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.68 -6.91 -0.35 2.45e-11 Asymmetrical dimethylarginine levels; LIHC cis rs425277 0.628 rs262662 chr1:2085033 A/G cg03732007 chr1:2071316 PRKCZ 0.35 6.05 0.31 3.78e-9 Height; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg07157834 chr1:205819609 PM20D1 0.65 9.71 0.46 7.5599999999999994e-20 Menarche (age at onset); LIHC trans rs877282 0.891 rs10904557 chr10:797490 C/T cg22713356 chr15:30763199 NA -1.25 -11.87 -0.54 1.92e-27 Uric acid levels; LIHC cis rs12477438 0.501 rs9941561 chr2:99753829 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.55 0.64 1.25e-41 Chronic sinus infection; LIHC cis rs875971 0.862 rs778734 chr7:65814849 C/G cg11764359 chr7:65958608 NA 0.85 15.2 0.64 3.07e-40 Aortic root size; LIHC cis rs912057 0.671 rs1294427 chr6:6744546 T/G cg06612196 chr6:6737390 NA 0.51 9.77 0.47 4.85e-20 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs9814567 1.000 rs4535272 chr3:134299916 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.89 0.3 9.44e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs882732 1.000 rs7159121 chr14:95040935 G/T cg14866387 chr14:95027382 SERPINA4 -0.48 -6.45 -0.33 3.82e-10 Blood protein levels; LIHC cis rs7412746 0.658 rs11204739 chr1:150865760 A/G cg15448220 chr1:150897856 SETDB1 0.44 6.97 0.35 1.64e-11 Melanoma; LIHC cis rs2549003 1.000 rs6894655 chr5:131818649 T/C cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.25e-20 Asthma (sex interaction); LIHC cis rs763121 0.813 rs2179143 chr22:39037984 A/G cg14440974 chr22:39074834 NA -0.34 -5.74 -0.3 2.14e-8 Menopause (age at onset); LIHC cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs1046896 0.519 rs9900369 chr17:80829807 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.41 6.25 0.32 1.2e-9 Glycated hemoglobin levels; LIHC cis rs763121 0.853 rs6001175 chr22:39018334 T/C cg21395723 chr22:39101663 GTPBP1 0.4 6.83 0.35 3.88e-11 Menopause (age at onset); LIHC cis rs2286503 0.839 rs2270103 chr7:22862722 C/T cg11367502 chr7:22862612 TOMM7 0.45 7.51 0.38 5.08e-13 Fibrinogen; LIHC cis rs7577696 0.524 rs12991444 chr2:32265125 G/T cg02381751 chr2:32503542 YIPF4 -0.43 -6.05 -0.31 3.73e-9 Inflammatory biomarkers; LIHC cis rs116095464 0.558 rs55833259 chr5:286728 G/A cg22857025 chr5:266934 NA -1.52 -15.89 -0.65 5.89e-43 Breast cancer; LIHC cis rs3736485 0.966 rs2124876 chr15:51906162 T/C cg08986416 chr15:51914746 DMXL2 -0.41 -6.11 -0.31 2.69e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs360798 0.512 rs360801 chr2:62955387 C/T cg17519650 chr2:63277830 OTX1 0.53 8.13 0.4 7.83e-15 Coronary artery disease; LIHC cis rs9300255 0.602 rs1716167 chr12:123651162 C/T cg00376283 chr12:123451042 ABCB9 -0.64 -7.43 -0.37 8.83e-13 Neutrophil percentage of white cells; LIHC cis rs826838 0.935 rs4583043 chr12:38645147 T/G cg13010199 chr12:38710504 ALG10B 0.64 7.58 0.38 3.38e-13 Heart rate; LIHC cis rs10792665 0.640 rs3763814 chr11:82612842 C/G cg24227371 chr11:82718527 RAB30 -0.27 -6.24 -0.32 1.28e-9 Obesity-related traits; LIHC cis rs11122272 0.735 rs2749706 chr1:231527170 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.62 -0.5 5.69e-23 Hemoglobin concentration; LIHC cis rs10751667 0.643 rs7396407 chr11:929374 A/T cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC cis rs6596100 0.500 rs35534543 chr5:132160057 C/T cg02081065 chr5:132209139 LEAP2 0.28 5.77 0.3 1.81e-8 Breast cancer; LIHC cis rs7614311 0.689 rs56329572 chr3:63846672 G/A cg22134162 chr3:63841271 THOC7 -0.56 -6.38 -0.33 5.62e-10 Lung function (FVC);Lung function (FEV1); LIHC cis rs4665809 1.000 rs2289022 chr2:26350136 G/T cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg26338869 chr17:61819248 STRADA 0.54 7.22 0.36 3.37e-12 Height; LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05091115 chr10:65280959 REEP3 -0.44 -6.32 -0.32 7.95e-10 Pancreatic cancer; LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs6061231 0.518 rs639836 chr20:60926223 G/A cg06026331 chr20:60912101 LAMA5 -0.5 -8.56 -0.42 3.89e-16 Colorectal cancer; LIHC cis rs3540 0.618 rs11609 chr15:91043765 C/G cg22089800 chr15:90895588 ZNF774 -0.58 -7.93 -0.39 3.04e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs644799 1.000 rs7749 chr11:95565789 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.91 0.67 4.81e-47 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1797081 0.901 rs703059 chr10:16876402 G/A cg23933602 chr10:16859644 RSU1 0.97 18.73 0.71 2.23e-54 Platelet distribution width; LIHC cis rs6754311 0.513 rs1438304 chr2:136503157 A/G cg17750252 chr2:136567154 LCT 0.33 5.77 0.3 1.81e-8 Mosquito bite size; LIHC cis rs9381040 0.655 rs9394756 chr6:41016183 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.46 -0.33 3.6e-10 Alzheimer's disease (late onset); LIHC cis rs4718428 0.705 rs12536410 chr7:66254290 G/A cg12165864 chr7:66369176 NA -0.47 -6.76 -0.34 5.8200000000000003e-11 Corneal structure; LIHC cis rs769267 0.930 rs2301786 chr19:19413947 A/G cg21559469 chr19:19431446 KIAA0892;SF4 0.42 5.9 0.3 8.68e-9 Tonsillectomy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08576880 chr16:1359158 UBE2I -0.46 -6.52 -0.33 2.53e-10 Pancreatic cancer; LIHC cis rs1866706 1.000 rs4757953 chr11:12874513 C/T cg25843174 chr11:12811716 TEAD1 0.31 6.64 0.34 1.25e-10 Intelligence (multi-trait analysis); LIHC cis rs2302190 1.000 rs8065388 chr17:56562132 C/T cg05425664 chr17:57184151 TRIM37 -0.5 -6.27 -0.32 1.07e-9 Vitamin D levels; LIHC cis rs1577917 0.655 rs2758849 chr6:86344296 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.23 -0.32 1.39e-9 Response to antipsychotic treatment; LIHC cis rs1401999 0.724 rs1016752 chr3:183665062 C/G cg01324343 chr3:183735012 ABCC5 -0.76 -11.64 -0.53 1.27e-26 Anterior chamber depth; LIHC cis rs2455601 0.744 rs7938995 chr11:8975675 T/G cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -5.88 -0.3 9.5e-9 Schizophrenia; LIHC cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg23982607 chr1:1823379 GNB1 0.67 13.14 0.58 3.35e-32 Body mass index; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.47 -7.5 -0.38 5.6e-13 Prudent dietary pattern; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.87 0.8 1.08e-78 Prudent dietary pattern; LIHC cis rs919433 0.680 rs2564389 chr2:198260098 A/T cg10820045 chr2:198174542 NA 0.54 8.7 0.43 1.47e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs5753618 0.519 rs5997939 chr22:31677130 C/G cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg12310025 chr6:25882481 NA -0.64 -9.08 -0.44 8.7e-18 Blood metabolite levels; LIHC cis rs12477438 0.798 rs6712338 chr2:99585457 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.58 -0.53 2.12e-26 Chronic sinus infection; LIHC cis rs8077889 0.672 rs3785810 chr17:41850689 C/G cg26893861 chr17:41843967 DUSP3 1.06 19.05 0.72 1.18e-55 Triglycerides; LIHC cis rs847851 0.617 rs3807051 chr6:34922439 T/C cg13137465 chr6:34857473 ANKS1A 0.67 7.34 0.37 1.6e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs2710642 0.564 rs6752597 chr2:62823444 T/C cg17519650 chr2:63277830 OTX1 0.46 7.23 0.36 3.24e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1448094 0.512 rs6539924 chr12:86236935 T/C cg02569458 chr12:86230093 RASSF9 0.48 6.36 0.33 6.43e-10 Major depressive disorder; LIHC cis rs8017423 0.967 rs11624725 chr14:90713609 G/T cg04374321 chr14:90722782 PSMC1 -0.73 -14.0 -0.6 1.63e-35 Mortality in heart failure; LIHC cis rs9911578 0.805 rs12601867 chr17:56455260 C/G cg05425664 chr17:57184151 TRIM37 0.52 7.46 0.37 7.39e-13 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.15 -0.44 5.33e-18 Bipolar disorder; LIHC cis rs10504229 0.679 rs2218271 chr8:58052446 T/A cg02290350 chr8:58132656 NA 0.32 6.91 0.35 2.35e-11 Developmental language disorder (linguistic errors); LIHC cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9640161 0.789 rs2373751 chr7:150021599 G/C cg10018233 chr7:150070692 REPIN1 0.55 8.5 0.42 5.96e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs67311347 1.000 rs7612015 chr3:40399974 A/C cg09455208 chr3:40491958 NA 0.33 6.55 0.33 2.06e-10 Renal cell carcinoma; LIHC cis rs2637266 0.935 rs751770 chr10:78393956 A/G cg18941641 chr10:78392320 NA 0.29 6.33 0.32 7.54e-10 Pulmonary function; LIHC cis rs1144333 0.655 rs1144337 chr1:76278877 A/G cg22875332 chr1:76189707 ACADM -0.41 -6.7 -0.34 8.62e-11 Attention function in attention deficit hyperactive disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25789201 chr7:72395803 POM121 0.48 7.37 0.37 1.31e-12 Cognitive function; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg19575813 chr18:46476937 SMAD7 -0.4 -6.09 -0.31 2.97e-9 Alopecia areata; LIHC cis rs4650994 0.593 rs12568310 chr1:178514622 C/T cg05350800 chr1:178550844 NA -0.35 -7.47 -0.37 6.85e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs7945718 0.806 rs7927346 chr11:12835835 C/T cg25843174 chr11:12811716 TEAD1 0.33 7.77 0.39 9.1e-14 Educational attainment (years of education); LIHC cis rs7224737 1.000 rs2014521 chr17:40283413 C/G cg02450064 chr17:40260053 DHX58 -0.29 -6.03 -0.31 4.3e-9 Fibrinogen levels; LIHC cis rs826838 0.935 rs10875816 chr12:38955014 C/A cg13010199 chr12:38710504 ALG10B 0.6 7.48 0.38 6.18e-13 Heart rate; LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs2138798 0.560 rs11899838 chr2:63478136 C/T cg17519650 chr2:63277830 OTX1 0.48 5.99 0.31 5.38e-9 Obesity-related traits; LIHC cis rs9517320 0.517 rs4772097 chr13:99194652 C/A cg07423050 chr13:99094983 FARP1 -0.48 -8.1 -0.4 9.68e-15 Longevity; LIHC cis rs6684514 1.000 rs12038217 chr1:156248297 C/T cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27458888 chr15:25684578 UBE3A 0.39 6.38 0.33 5.67e-10 Cognitive function; LIHC cis rs12644436 0.965 rs10024946 chr4:88790584 A/G cg06891869 chr4:88767617 MEPE 0.31 5.72 0.3 2.28e-8 HIV-1 viral setpoint; LIHC cis rs6456156 0.586 rs1358882 chr6:167467101 G/A cg12798992 chr6:167411361 FGFR1OP 0.43 6.62 0.34 1.39e-10 Primary biliary cholangitis; LIHC trans rs7937682 0.961 rs7106104 chr11:111635655 T/C cg18187862 chr3:45730750 SACM1L -0.56 -6.45 -0.33 3.84e-10 Primary sclerosing cholangitis; LIHC cis rs2274273 0.804 rs28428911 chr14:55843596 G/T cg01864836 chr14:55583639 NA -0.38 -6.69 -0.34 9.03e-11 Protein biomarker; LIHC cis rs2455799 0.634 rs4685266 chr3:15908766 A/G cg12698662 chr3:15914712 MIR563 -0.38 -6.99 -0.35 1.47e-11 Mean platelet volume; LIHC cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.89 0.3 9e-9 Menopause (age at onset); LIHC cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg02290350 chr8:58132656 NA 0.35 8.24 0.41 3.84e-15 Developmental language disorder (linguistic errors); LIHC cis rs2354432 0.891 rs2165743 chr1:146690319 C/T cg25205988 chr1:146714368 CHD1L 0.91 12.6 0.56 3.57e-30 Mitochondrial DNA levels; LIHC cis rs10508774 0.925 rs56391924 chr10:32745248 A/C cg01819863 chr10:32635814 EPC1 0.65 6.01 0.31 4.72e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1580019 0.922 rs1376289 chr7:32486980 C/G cg07520158 chr7:32535189 LSM5;AVL9 -0.49 -6.67 -0.34 1.05e-10 Cognitive ability; LIHC cis rs5769707 0.681 rs9616329 chr22:50026314 G/A cg01652190 chr22:50026171 C22orf34 -0.32 -7.31 -0.37 1.93e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2153535 0.580 rs6913100 chr6:8456855 A/G cg07606381 chr6:8435919 SLC35B3 0.83 12.75 0.57 1.01e-30 Motion sickness; LIHC cis rs55665837 0.961 rs11023237 chr11:14500334 G/A cg19336497 chr11:14380999 RRAS2 -0.45 -8.08 -0.4 1.1e-14 Vitamin D levels; LIHC cis rs2839627 0.561 rs1107830 chr21:44275097 G/A cg03543861 chr21:44258195 NA 0.53 8.66 0.42 1.9e-16 Information processing speed; LIHC cis rs7568458 0.709 rs11895399 chr2:85753806 C/A cg02493740 chr2:85810744 VAMP5 -0.45 -7.58 -0.38 3.19e-13 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7589728 1.000 rs6720809 chr2:88528943 T/C cg04511125 chr2:88470314 THNSL2 0.76 7.03 0.36 1.15e-11 Plasma clusterin levels; LIHC cis rs735396 0.770 rs1169315 chr12:121443753 T/G cg25281562 chr12:121454272 C12orf43 0.36 6.15 0.32 2.16e-9 N-glycan levels; LIHC trans rs1814175 0.647 rs28456013 chr11:50047629 T/C cg03929089 chr4:120376271 NA -0.61 -10.45 -0.49 2.26e-22 Height; LIHC cis rs2153535 0.623 rs6597338 chr6:8533508 A/C cg23788917 chr6:8435910 SLC35B3 0.63 9.02 0.44 1.37e-17 Motion sickness; LIHC cis rs7131987 0.621 rs57803026 chr12:29497506 G/A cg14222432 chr12:29376421 FAR2 0.33 6.26 0.32 1.13e-9 QT interval; LIHC cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg13395646 chr4:1353034 KIAA1530 0.63 9.11 0.44 7.15e-18 Obesity-related traits; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg13047869 chr3:10149882 C3orf24 0.51 5.88 0.3 9.55e-9 Alzheimer's disease; LIHC cis rs79057730 0.599 rs4333501 chr7:803244 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.77 9.04 0.44 1.18e-17 Initial pursuit acceleration; LIHC trans rs2243480 1.000 rs6958420 chr7:65751171 A/G cg10756647 chr7:56101905 PSPH -1.04 -12.61 -0.56 3.42e-30 Diabetic kidney disease; LIHC cis rs17826219 0.500 rs28452421 chr17:29083980 G/A cg14067834 chr17:29058358 SUZ12P 0.69 6.86 0.35 3.31e-11 Body mass index; LIHC cis rs8180040 0.903 rs11130124 chr3:47292183 T/C cg27129171 chr3:47204927 SETD2 0.69 11.98 0.54 7.23e-28 Colorectal cancer; LIHC cis rs8180040 0.627 rs9821119 chr3:47198437 C/G cg27129171 chr3:47204927 SETD2 0.58 9.54 0.46 2.83e-19 Colorectal cancer; LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg27432699 chr2:27873401 GPN1 -0.56 -8.23 -0.41 3.85e-15 Total body bone mineral density; LIHC cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg18404041 chr3:52824283 ITIH1 -0.55 -8.86 -0.43 4.49e-17 Bipolar disorder; LIHC cis rs875971 0.862 rs10282433 chr7:65721439 G/A cg18252515 chr7:66147081 NA 0.45 6.5 0.33 2.83e-10 Aortic root size; LIHC cis rs6964587 1.000 rs7785971 chr7:91736794 T/A cg17063962 chr7:91808500 NA 1.04 20.83 0.75 8.28e-63 Breast cancer; LIHC cis rs17685 0.753 rs13240967 chr7:75658197 C/T cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.24 0.32 1.31e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs17685 0.725 rs6947068 chr7:75662056 T/C cg19862616 chr7:65841803 NCRNA00174 -0.91 -18.61 -0.71 6.98e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10744422 1.000 rs2343108 chr12:123331301 C/T cg22842854 chr12:123319900 HIP1R -0.74 -9.79 -0.47 4.11e-20 Schizophrenia; LIHC cis rs1018836 0.828 rs10956730 chr8:91597428 T/G cg16814680 chr8:91681699 NA -0.56 -8.91 -0.43 3.11e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2991971 0.747 rs2492841 chr1:45894891 G/T cg24296786 chr1:45957014 TESK2 -0.52 -8.01 -0.4 1.77e-14 High light scatter reticulocyte count; LIHC cis rs13256369 0.802 rs11249885 chr8:8562008 C/T cg17143192 chr8:8559678 CLDN23 0.79 14.03 0.6 1.24e-35 Obesity-related traits; LIHC cis rs10493773 0.748 rs6576784 chr1:86149476 G/A cg17807903 chr1:86174739 ZNHIT6 -0.55 -10.17 -0.48 2.08e-21 Urate levels in overweight individuals; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18222961 chr2:48009935 MSH6 0.42 6.06 0.31 3.54e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs344364 0.511 rs1742467 chr16:1950187 G/T cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC trans rs9641123 0.639 rs2214872 chr7:93250631 C/T cg09745688 chr16:2908918 PRSS22 -0.36 -6.34 -0.32 7.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs74544699 0.826 rs74499711 chr4:74842764 G/A cg15398841 chr4:74847761 PF4 0.54 6.08 0.31 3.29e-9 Growth-regulated protein alpha levels; LIHC cis rs733592 0.560 rs2158515 chr12:48507668 T/C cg21466736 chr12:48725269 NA 0.34 5.96 0.31 6.37e-9 Plateletcrit; LIHC cis rs2070488 0.745 rs7649153 chr3:38467753 T/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.57 8.02 0.4 1.73e-14 Electrocardiographic conduction measures; LIHC cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg22800045 chr5:56110881 MAP3K1 0.65 8.42 0.41 1.05e-15 Initial pursuit acceleration; LIHC cis rs600806 0.751 rs1933182 chr1:109999838 A/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.83 -0.3 1.27e-8 Intelligence (multi-trait analysis); LIHC cis rs9640161 0.742 rs2108851 chr7:150019634 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.31 -0.41 2.26e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs9916302 0.904 rs4794813 chr17:37670994 A/T cg00129232 chr17:37814104 STARD3 -0.42 -6.77 -0.34 5.55e-11 Glomerular filtration rate (creatinine); LIHC cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs3736485 0.934 rs4775952 chr15:51869056 T/C cg08986416 chr15:51914746 DMXL2 -0.41 -6.06 -0.31 3.5e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7511006 1.000 rs7290710 chr22:50677454 C/T cg16473166 chr22:50639996 SELO 0.51 7.2 0.36 3.75e-12 Obesity-related traits; LIHC cis rs2370759 0.945 rs10508773 chr10:32575444 C/T cg05361325 chr10:32636312 EPC1 -0.52 -6.41 -0.33 4.77e-10 Sexual dysfunction (female); LIHC cis rs7129220 0.512 rs58652557 chr11:10121925 C/G cg01453529 chr11:10209919 SBF2 -0.39 -6.9 -0.35 2.47e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs3806843 0.735 rs2530235 chr5:140072647 G/T cg19875535 chr5:140030758 IK -0.41 -6.7 -0.34 8.36e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs75908454 1.000 rs79558633 chr6:169819490 C/T cg19338460 chr6:170058176 WDR27 -0.85 -7.44 -0.37 8.17e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs1775715 0.677 rs2491272 chr10:32186783 A/G cg14930904 chr10:32216787 ARHGAP12 0.36 6.29 0.32 9.98e-10 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs56011263 0.687 rs11734460 chr4:705074 C/T cg12575136 chr18:32820987 ZNF397 0.48 7.12 0.36 6.25e-12 White blood cell count; LIHC cis rs4665809 1.000 rs1560868 chr2:26281459 A/T cg26119090 chr2:26468346 HADHA;HADHB 0.73 9.37 0.45 1.03e-18 Gut microbiome composition (summer); LIHC trans rs526821 0.595 rs565859 chr11:55297367 T/C cg03929089 chr4:120376271 NA -0.46 -7.03 -0.36 1.11e-11 Pediatric bone mineral density (spine); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00776160 chr1:149815087 HIST2H2AA3;HIST2H2AA4 0.41 6.65 0.34 1.18e-10 Cognitive function; LIHC cis rs738322 0.555 rs2284063 chr22:38544298 C/T cg25457927 chr22:38595422 NA 0.35 8.55 0.42 4.32e-16 Cutaneous nevi; LIHC cis rs1348850 0.634 rs1534304 chr2:178489264 C/T cg27490568 chr2:178487706 NA 0.79 10.26 0.49 1.02e-21 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs35110281 0.807 rs2838325 chr21:45014284 A/T cg04455712 chr21:45112962 RRP1B -0.42 -7.35 -0.37 1.45e-12 Mean corpuscular volume; LIHC cis rs7639513 0.520 rs79141906 chr3:12711977 A/C cg23032965 chr3:12705835 RAF1 0.6 6.61 0.34 1.51e-10 Itch intensity from mosquito bite; LIHC cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg24549020 chr5:56110836 MAP3K1 0.5 6.46 0.33 3.61e-10 Initial pursuit acceleration; LIHC cis rs1986734 0.560 rs4859683 chr4:77419073 C/T cg24201034 chr4:77507246 SHROOM3 -0.38 -6.12 -0.31 2.62e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs7520050 0.966 rs12564541 chr1:46380237 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.37e-8 Red blood cell count;Reticulocyte count; LIHC trans rs1814175 0.817 rs11040474 chr11:49708441 G/A cg18944383 chr4:111397179 ENPEP 0.25 6.32 0.32 7.95e-10 Height; LIHC trans rs4596713 0.538 rs4421408 chr9:71760884 G/T cg16512924 chr15:28394682 HERC2 0.39 6.27 0.32 1.07e-9 Headache; LIHC cis rs7044106 0.762 rs1530370 chr9:123424552 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 8.09 0.4 1.03e-14 Hip circumference adjusted for BMI; LIHC cis rs11864453 0.612 rs12924413 chr16:72129745 T/C cg16558253 chr16:72132732 DHX38 -0.41 -6.6 -0.34 1.61e-10 Fibrinogen levels; LIHC cis rs28830936 0.934 rs3959569 chr15:42115747 G/C cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.86 -0.3 1.09e-8 Diastolic blood pressure; LIHC cis rs1163251 0.902 rs511059 chr1:120217081 G/T cg19096424 chr1:120255104 PHGDH 0.63 7.84 0.39 5.87e-14 Blood metabolite levels; LIHC cis rs2180341 0.960 rs9375503 chr6:127677071 T/C cg24812749 chr6:127587940 RNF146 1.05 15.47 0.64 2.58e-41 Breast cancer; LIHC cis rs9303401 0.659 rs12948133 chr17:56673602 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.34 0.58 5.79e-33 Cognitive test performance; LIHC cis rs9872999 1 rs9872999 chr3:133457514 C/T cg18769074 chr3:133464867 TF 0.27 6.1 0.31 2.9e-9 Iron status biomarkers; LIHC trans rs17685 0.753 rs6464999 chr7:75787315 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2153535 0.580 rs6421949 chr6:8531769 G/A cg07606381 chr6:8435919 SLC35B3 0.78 11.34 0.52 1.64e-25 Motion sickness; LIHC cis rs1775715 0.707 rs2799019 chr10:32142850 C/T cg14930904 chr10:32216787 ARHGAP12 0.37 6.48 0.33 3.2e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs16854884 0.586 rs13081286 chr3:143723757 A/T cg06585982 chr3:143692056 C3orf58 0.55 7.13 0.36 6.01e-12 Economic and political preferences (feminism/equality); LIHC cis rs611744 0.967 rs662591 chr8:109211358 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs11671005 0.735 rs34873624 chr19:58943402 G/A cg25952890 chr19:58913133 NA 0.7 7.64 0.38 2.23e-13 Mean platelet volume; LIHC cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg13301601 chr7:774633 HEATR2 -0.4 -5.71 -0.3 2.44e-8 Cerebrospinal P-tau181p levels; LIHC cis rs12413816 0.963 rs10796116 chr10:13762786 C/T cg16485048 chr10:13749193 FRMD4A -0.57 -8.77 -0.43 8.66e-17 Red cell distribution width; LIHC cis rs6963495 0.615 rs2697021 chr7:105151029 A/C cg19920283 chr7:105172520 RINT1 0.48 6.13 0.31 2.49e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6687430 0.526 rs12127400 chr1:10613660 C/T cg17425144 chr1:10567563 PEX14 0.46 8.51 0.42 5.51e-16 Hand grip strength; LIHC cis rs28374715 0.662 rs513280 chr15:41482800 T/C cg18705301 chr15:41695430 NDUFAF1 0.86 9.63 0.46 1.43e-19 Ulcerative colitis; LIHC cis rs2153535 0.580 rs7767780 chr6:8453462 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.89e-27 Motion sickness; LIHC cis rs6748734 1.000 rs4675874 chr2:241819796 A/G cg08694578 chr2:241835147 C2orf54 0.48 6.6 0.34 1.57e-10 Urinary metabolites; LIHC cis rs1577917 1.000 rs12199784 chr6:86726808 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.11 -0.48 3.3e-21 Response to antipsychotic treatment; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.68 9.78 0.47 4.28e-20 Lymphocyte counts; LIHC cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg24250549 chr1:154909240 PMVK -0.69 -11.23 -0.52 3.92e-25 Prostate cancer; LIHC cis rs74233809 1.000 rs74233809 chr10:104913940 T/C cg03493300 chr10:104813866 CNNM2 0.46 6.04 0.31 3.94e-9 Birth weight; LIHC cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg07061783 chr6:25882402 NA 0.42 5.73 0.3 2.15e-8 Blood metabolite levels; LIHC cis rs2257205 0.667 rs6503876 chr17:56814988 G/C cg05425664 chr17:57184151 TRIM37 -0.6 -6.66 -0.34 1.08e-10 Pancreatic cancer; LIHC cis rs7552404 0.924 rs1858536 chr1:76161595 G/T cg10523679 chr1:76189770 ACADM 0.67 9.95 0.47 1.22e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1034435 0.755 rs5768681 chr22:48894501 C/T cg05992904 chr22:48892994 FAM19A5 -0.53 -10.94 -0.51 4.33e-24 Late-onset Alzheimer's disease; LIHC cis rs7208859 0.673 rs2269915 chr17:29233344 C/T cg14067834 chr17:29058358 SUZ12P 0.67 6.54 0.33 2.2e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.593 rs12216730 chr8:58003894 C/T cg02290350 chr8:58132656 NA 0.31 6.73 0.34 7.15e-11 Developmental language disorder (linguistic errors); LIHC cis rs9640161 0.789 rs2373751 chr7:150021599 G/C cg27494647 chr7:150038898 RARRES2 0.33 5.98 0.31 5.68e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg07092213 chr7:1199455 ZFAND2A -0.43 -6.38 -0.33 5.85e-10 Longevity;Endometriosis; LIHC cis rs3784262 0.934 rs4646611 chr15:58265083 T/C cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.24 -0.32 1.26e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs4268898 0.931 rs2551121 chr2:24539967 T/C cg06627628 chr2:24431161 ITSN2 -0.56 -7.92 -0.39 3.31e-14 Asthma; LIHC cis rs78456975 0.941 rs13412229 chr2:1520381 C/T cg01028140 chr2:1542097 TPO -0.53 -5.86 -0.3 1.1e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs807029 0.533 rs722435 chr10:102745062 G/T cg17130504 chr10:102756923 LZTS2 0.56 7.8 0.39 7.35e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs6674176 0.597 rs4031031 chr1:44393533 C/T cg12908607 chr1:44402522 ARTN -0.5 -8.64 -0.42 2.13e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs10411161 0.702 rs7251929 chr19:52389258 C/T cg22319618 chr22:45562946 NUP50 -0.62 -8.57 -0.42 3.59e-16 Breast cancer; LIHC cis rs35306767 0.903 rs765867 chr10:869901 G/T cg26597838 chr10:835615 NA 1.14 13.62 0.59 4.65e-34 Eosinophil percentage of granulocytes; LIHC cis rs11122272 0.735 rs2024878 chr1:231528415 A/C cg06096015 chr1:231504339 EGLN1 -0.44 -8.19 -0.4 5.26e-15 Hemoglobin concentration; LIHC cis rs3008870 1.000 rs3008853 chr1:67385488 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.45 0.66 3.47e-45 Lymphocyte percentage of white cells; LIHC cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg11764359 chr7:65958608 NA -0.58 -5.98 -0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs922107 0.713 rs1380416 chr1:89949213 A/G cg15422784 chr1:90023713 LRRC8B 0.41 6.43 0.33 4.3e-10 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7959452 0.557 rs7980883 chr12:69778914 C/T cg22834771 chr12:69754056 YEATS4 -0.52 -9.23 -0.45 2.82e-18 Blood protein levels; LIHC cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg05025164 chr4:1340916 KIAA1530 -0.4 -5.96 -0.31 6.35e-9 Obesity-related traits; LIHC trans rs1459104 0.673 rs7118132 chr11:55126517 C/T cg03929089 chr4:120376271 NA 0.51 6.98 0.35 1.5e-11 Body mass index; LIHC trans rs1814175 0.754 rs28593359 chr11:50042357 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.41e-11 Height; LIHC cis rs7904368 0.659 rs3740169 chr10:16873547 C/T cg14835575 chr10:16859367 RSU1 0.3 5.77 0.3 1.81e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs12458462 0.509 rs3786241 chr18:77494328 A/C cg11879182 chr18:77439856 CTDP1 0.59 8.36 0.41 1.58e-15 Monocyte count; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg11494091 chr17:61959527 GH2 -0.44 -8.16 -0.4 6.52e-15 Prudent dietary pattern; LIHC cis rs6499255 0.951 rs16959025 chr16:69695589 G/T cg15192750 chr16:69999425 NA -0.45 -6.01 -0.31 4.86e-9 IgE levels; LIHC cis rs2607426 0.681 rs1531063 chr19:41225319 C/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.5 -5.97 -0.31 6.06e-9 Blood protein levels; LIHC cis rs3736485 0.932 rs8037167 chr15:51918126 G/T cg08986416 chr15:51914746 DMXL2 -0.46 -6.8 -0.35 4.61e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs459482 0.534 rs458255 chr21:42801128 G/A cg14166395 chr21:42792516 MX1 0.51 7.03 0.36 1.16e-11 IgG glycosylation; LIHC cis rs3744061 0.557 rs9889862 chr17:74647976 A/G cg13533061 chr17:74712429 JMJD6 -0.3 -6.17 -0.32 1.88e-9 Retinal arteriolar caliber; LIHC cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg12310025 chr6:25882481 NA -0.61 -7.36 -0.37 1.4e-12 Intelligence (multi-trait analysis); LIHC cis rs2439831 1.000 rs690436 chr15:43761205 T/C cg15269541 chr15:43626905 ADAL -0.3 -5.88 -0.3 9.9e-9 Lung cancer in ever smokers; LIHC cis rs13040088 0.935 rs62200158 chr20:61557906 C/T cg23096297 chr20:61557774 DIDO1 0.85 11.72 0.54 6.66e-27 Menopause (age at onset); LIHC cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg09222892 chr1:25734099 RHCE -0.47 -8.83 -0.43 5.58e-17 Erythrocyte sedimentation rate; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10983056 chr13:113344077 ATP11A 0.47 6.66 0.34 1.07e-10 Lung function (FEV1/FVC); LIHC cis rs9443189 0.570 rs6903448 chr6:76173832 C/T cg01950844 chr6:76311363 SENP6 0.65 8.24 0.41 3.74e-15 Prostate cancer; LIHC cis rs6424115 0.830 rs2502999 chr1:24198321 A/G cg15997130 chr1:24165203 NA 0.38 7.78 0.39 8.76e-14 Immature fraction of reticulocytes; LIHC trans rs11098499 0.863 rs2170276 chr4:120485824 A/C cg25214090 chr10:38739885 LOC399744 0.59 9.36 0.45 1.08e-18 Corneal astigmatism; LIHC cis rs713477 0.967 rs6573032 chr14:55913776 A/G cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.45e-16 Pediatric bone mineral content (femoral neck); LIHC trans rs7246657 0.943 rs4802766 chr19:37981933 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.15 0.32 2.16e-9 Coronary artery calcification; LIHC cis rs919433 0.679 rs6708239 chr2:198525084 A/G cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs1814175 0.817 rs1621090 chr11:49895868 C/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs904251 0.797 rs2776878 chr6:37487273 G/A cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.39e-12 Cognitive performance; LIHC cis rs8072100 1.000 rs3809868 chr17:45750596 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 0.38 5.91 0.3 8.44e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7187994 0.836 rs16974519 chr16:84782750 A/C cg07647771 chr16:84786436 USP10 -0.34 -6.7 -0.34 8.38e-11 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg06656553 chr16:89960601 TCF25 -0.43 -5.74 -0.3 2.05e-8 Skin colour saturation; LIHC cis rs9399135 0.967 rs7773126 chr6:135318390 A/G cg24558204 chr6:135376177 HBS1L 0.38 6.33 0.32 7.67e-10 Red blood cell count; LIHC cis rs1568889 0.838 rs10458896 chr11:28057957 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 13.84 0.6 6.95e-35 Bipolar disorder; LIHC cis rs6500602 0.647 rs1641868 chr16:4594503 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.44 6.54 0.33 2.21e-10 Schizophrenia; LIHC cis rs1577917 0.958 rs12216074 chr6:86520002 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -7.91 -0.39 3.62e-14 Response to antipsychotic treatment; LIHC cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg02187348 chr16:89574699 SPG7 0.63 10.29 0.49 8.39e-22 Multiple myeloma (IgH translocation); LIHC trans rs7618501 0.635 rs7635002 chr3:49989155 T/G cg21659725 chr3:3221576 CRBN 0.7 10.98 0.51 3.09e-24 Intelligence (multi-trait analysis); LIHC cis rs4407350 0.967 rs5765731 chr22:44922759 C/T cg26276947 chr22:44892394 LDOC1L 0.33 5.94 0.31 7.18e-9 Intelligence (multi-trait analysis); LIHC cis rs910316 0.935 rs175448 chr14:75591071 G/A cg11812906 chr14:75593930 NEK9 -0.77 -15.14 -0.63 5.41e-40 Height; LIHC cis rs1707322 1.000 rs1768801 chr1:46549137 C/G cg06784218 chr1:46089804 CCDC17 -0.37 -6.74 -0.34 6.8e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs644799 0.965 rs3016295 chr11:95554311 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.84 0.3 1.21e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs17021463 0.615 rs4626213 chr4:95297241 G/A cg11021082 chr4:95130006 SMARCAD1 0.43 7.18 0.36 4.27e-12 Testicular germ cell tumor; LIHC cis rs929354 0.685 rs7807856 chr7:156934498 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.74 -0.3 2.1e-8 Body mass index; LIHC cis rs2637266 0.935 rs2252661 chr10:78404793 A/G cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs875971 0.862 rs1083554 chr7:65852341 T/C cg11764359 chr7:65958608 NA 0.78 13.44 0.59 2.44e-33 Aortic root size; LIHC cis rs4450131 0.522 rs3781460 chr10:126342919 A/G cg20435097 chr10:126320824 FAM53B -0.67 -12.26 -0.55 6.68e-29 White blood cell count (basophil); LIHC cis rs2834188 1.000 rs2252930 chr21:34704201 C/G cg14352951 chr21:34696688 IFNAR1 -0.51 -6.73 -0.34 7.03e-11 Narcolepsy; LIHC cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs754466 0.606 rs7084705 chr10:79596675 A/G cg17075019 chr10:79541650 NA -0.74 -11.48 -0.53 4.86e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8060686 0.516 rs11075670 chr16:68288393 C/G cg09835421 chr16:68378352 PRMT7 -0.47 -5.77 -0.3 1.75e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs1577917 0.958 rs4707236 chr6:86583967 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.82 -0.39 6.44e-14 Response to antipsychotic treatment; LIHC cis rs11758351 1.000 rs11758351 chr6:26203910 T/G cg03854865 chr6:26224070 HIST1H3E 0.62 7.01 0.35 1.3e-11 Gout;Renal underexcretion gout; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.65 0.38 2.03e-13 Height; LIHC trans rs916888 0.610 rs199454 chr17:44800110 G/A cg22968622 chr17:43663579 NA -0.49 -7.11 -0.36 6.83e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg27170947 chr2:26402098 FAM59B -0.65 -8.36 -0.41 1.57e-15 Gut microbiome composition (summer); LIHC cis rs1801251 1.000 rs13035829 chr2:233604487 A/T cg08000102 chr2:233561755 GIGYF2 0.75 11.3 0.52 2.24e-25 Coronary artery disease; LIHC cis rs35110281 0.627 rs1595167 chr21:44965874 T/G cg04455712 chr21:45112962 RRP1B 0.39 6.54 0.33 2.22e-10 Mean corpuscular volume; LIHC cis rs8103278 0.507 rs3745802 chr19:46271177 G/T cg11657440 chr19:46296263 DMWD 0.62 11.44 0.53 7.14e-26 Coronary artery disease; LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.2 -0.32 1.65e-9 Total body bone mineral density; LIHC cis rs6598955 0.724 rs12096059 chr1:26596709 G/A cg04990556 chr1:26633338 UBXN11 -0.61 -9.95 -0.47 1.17e-20 Obesity-related traits; LIHC cis rs1048257 0.682 rs2582514 chr14:105413204 G/T cg15352829 chr14:105391018 PLD4 -0.44 -9.24 -0.45 2.61e-18 Systemic lupus erythematosus; LIHC cis rs2228479 0.850 rs12596934 chr16:89841605 T/G cg14709524 chr16:89940631 TCF25 0.47 5.85 0.3 1.13e-8 Skin colour saturation; LIHC cis rs7618501 0.699 rs6446187 chr3:49907111 C/A cg21467203 chr3:49911342 NA -0.51 -8.96 -0.44 2.09e-17 Intelligence (multi-trait analysis); LIHC cis rs10744422 0.925 rs897391 chr12:123326374 G/A cg25930673 chr12:123319894 HIP1R -0.86 -11.24 -0.52 3.86e-25 Schizophrenia; LIHC cis rs79839061 0.656 rs11726508 chr4:888937 C/T cg04824913 chr4:887549 GAK 0.61 7.68 0.38 1.71e-13 Intelligence (multi-trait analysis); LIHC cis rs5769707 0.777 rs8141219 chr22:50044546 A/G cg01652190 chr22:50026171 C22orf34 -0.35 -7.98 -0.4 2.3e-14 Monocyte count;Monocyte percentage of white cells; LIHC trans rs208520 1.000 rs12200490 chr6:66976084 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.67 7.02 0.35 1.23e-11 Exhaled nitric oxide output; LIHC cis rs7615952 0.599 rs67566088 chr3:125768973 C/A cg05084668 chr3:125655381 ALG1L -0.41 -6.38 -0.33 5.63e-10 Blood pressure (smoking interaction); LIHC cis rs4285214 0.715 rs10079692 chr5:124025450 A/G cg15082166 chr5:124005151 ZNF608 -0.41 -5.92 -0.31 7.68e-9 Survival in pancreatic cancer; LIHC cis rs1506636 0.511 rs62484466 chr7:123174880 T/A cg03229431 chr7:123269106 ASB15 0.41 7.99 0.4 2.11e-14 Plateletcrit;Platelet count; LIHC cis rs7927592 0.513 rs653056 chr11:68203625 T/C cg16797656 chr11:68205561 LRP5 0.6 10.91 0.51 5.64e-24 Total body bone mineral density; LIHC cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs9814567 1.000 rs3932818 chr3:134206069 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.37 -0.56 2.66e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg21724239 chr8:58056113 NA 0.56 7.39 0.37 1.1e-12 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.619 rs2302918 chr7:66000932 A/G cg18876405 chr7:65276391 NA 0.44 7.81 0.39 6.84e-14 Aortic root size; LIHC cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg18252515 chr7:66147081 NA -1.26 -17.06 -0.68 1.18e-47 Diabetic kidney disease; LIHC cis rs7027203 0.828 rs4344139 chr9:96600298 T/C cg13679303 chr9:96623674 NA -0.3 -6.67 -0.34 1.04e-10 DNA methylation (variation); LIHC cis rs9303401 0.614 rs2007993 chr17:56590643 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.9 11.72 0.54 6.56e-27 Cognitive test performance; LIHC cis rs1008375 0.931 rs3775926 chr4:17599837 G/A cg02297831 chr4:17616191 MED28 0.49 7.53 0.38 4.66e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs877282 0.898 rs11253340 chr10:764786 G/T cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs11122272 0.614 rs78172021 chr1:231525160 A/T cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC trans rs2727020 0.523 rs7948958 chr11:49506749 G/A cg15704280 chr7:45808275 SEPT13 0.79 11.77 0.54 4.32e-27 Coronary artery disease; LIHC cis rs4908768 0.906 rs12401496 chr1:8600401 C/T cg25722041 chr1:8623473 RERE 0.42 5.91 0.3 8.17e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3736485 0.932 rs11633395 chr15:51917957 G/T cg08986416 chr15:51914746 DMXL2 -0.47 -7.03 -0.36 1.16e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14471096 chr4:185570637 CCDC111;CASP3 0.43 6.12 0.31 2.58e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs763121 0.813 rs2179143 chr22:39037984 A/G cg06022373 chr22:39101656 GTPBP1 0.67 12.77 0.57 8.09e-31 Menopause (age at onset); LIHC cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg13126279 chr21:47581558 C21orf56 -0.4 -6.11 -0.31 2.72e-9 Testicular germ cell tumor; LIHC cis rs875971 0.964 rs55748098 chr7:65763618 T/C cg18252515 chr7:66147081 NA 0.42 6.03 0.31 4.17e-9 Aortic root size; LIHC cis rs2153535 0.580 rs7775909 chr6:8477778 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.03e-14 Motion sickness; LIHC cis rs28374715 0.528 rs7178360 chr15:41631175 T/A cg18705301 chr15:41695430 NDUFAF1 -1.21 -16.78 -0.67 1.55e-46 Ulcerative colitis; LIHC cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg21724239 chr8:58056113 NA 0.49 6.53 0.33 2.43e-10 Developmental language disorder (linguistic errors); LIHC cis rs3820068 0.705 rs72643694 chr1:15860185 C/T cg17385448 chr1:15911702 AGMAT 0.38 6.66 0.34 1.12e-10 Systolic blood pressure; LIHC trans rs13202860 1.000 rs34281235 chr6:87188343 C/T cg27326224 chr7:950474 ADAP1 -0.57 -6.32 -0.32 8.05e-10 Sexual dysfunction (female); LIHC cis rs9911578 0.967 rs8082544 chr17:57185807 C/T cg05425664 chr17:57184151 TRIM37 0.6 9.0 0.44 1.61e-17 Intelligence (multi-trait analysis); LIHC cis rs911555 0.504 rs8021368 chr14:104074810 G/A cg24130564 chr14:104152367 KLC1 -0.65 -12.0 -0.54 6.23e-28 Intelligence (multi-trait analysis); LIHC cis rs2286503 0.780 rs981792 chr7:22861639 C/A cg11367502 chr7:22862612 TOMM7 0.45 7.51 0.38 5.08e-13 Fibrinogen; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17808901 chr3:39093368 WDR48 0.49 6.78 0.34 5.36e-11 Pancreatic cancer; LIHC cis rs4730250 0.707 rs10953537 chr7:107027905 G/A cg02696742 chr7:106810147 HBP1 -0.5 -5.74 -0.3 2.1e-8 Osteoarthritis; LIHC cis rs9393692 0.905 rs6916289 chr6:26289122 A/T cg13736514 chr6:26305472 NA -0.38 -6.33 -0.32 7.86e-10 Educational attainment; LIHC cis rs7312933 1.000 rs10880230 chr12:42450253 G/A cg01256987 chr12:42539512 GXYLT1 -0.4 -6.55 -0.33 2.15e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs17401966 0.898 rs12757288 chr1:10323921 T/C cg19773385 chr1:10388646 KIF1B -0.4 -7.25 -0.36 2.89e-12 Hepatocellular carcinoma; LIHC cis rs2978263 0.689 rs16877110 chr8:30368430 G/T cg05780722 chr8:30327988 RBPMS -0.35 -6.77 -0.34 5.59e-11 Cognitive performance; LIHC cis rs9596863 0.950 rs1379827 chr13:54395414 A/C ch.13.53330881F chr13:54432880 NA 0.43 5.74 0.3 2.08e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1113500 0.933 rs12132785 chr1:108633083 A/T cg06207961 chr1:108661230 NA 0.38 7.48 0.37 6.47e-13 Growth-regulated protein alpha levels; LIHC trans rs12753920 0.703 rs1601021 chr1:92621413 A/G cg15668468 chr10:118892869 VAX1 0.43 6.15 0.32 2.19e-9 Systemic lupus erythematosus; LIHC cis rs9309473 0.607 rs7586361 chr2:73601606 G/A cg20560298 chr2:73613845 ALMS1 -0.47 -7.42 -0.37 9.42e-13 Metabolite levels; LIHC cis rs11252926 0.563 rs11252290 chr10:461989 C/T cg16346588 chr10:242978 ZMYND11 0.39 6.04 0.31 3.96e-9 Psychosis in Alzheimer's disease; LIHC cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg25072359 chr17:41440525 NA 0.38 6.12 0.31 2.63e-9 Menopause (age at onset); LIHC cis rs10504229 0.679 rs16921676 chr8:58052386 G/T cg20607798 chr8:58055168 NA 0.46 6.26 0.32 1.18e-9 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.572 rs58223482 chr3:10169746 G/C cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs2228479 0.850 rs2238527 chr16:89840708 C/A cg14709524 chr16:89940631 TCF25 0.47 5.85 0.3 1.13e-8 Skin colour saturation; LIHC cis rs34172651 0.517 rs3803716 chr16:24802325 C/T cg00152838 chr16:24741724 TNRC6A -0.53 -6.51 -0.33 2.74e-10 Intelligence (multi-trait analysis); LIHC cis rs2075371 1.000 rs2505 chr7:133979552 C/T cg20476274 chr7:133979776 SLC35B4 0.76 13.03 0.58 8.94e-32 Mean platelet volume; LIHC cis rs17826219 0.706 rs8071236 chr17:29100002 T/C cg14067834 chr17:29058358 SUZ12P 0.71 6.99 0.35 1.49e-11 Body mass index; LIHC cis rs6933660 0.800 rs963193 chr6:151789355 G/T cg14262678 chr6:151773367 RMND1;C6orf211 -0.48 -6.95 -0.35 1.86e-11 Menarche (age at onset); LIHC cis rs2073300 1.000 rs6132621 chr20:23442180 C/T cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11105298 0.891 rs12369685 chr12:89928905 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.49 -0.38 6.04e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs13118159 0.836 rs12647145 chr4:1338618 C/A cg13395646 chr4:1353034 KIAA1530 -0.6 -8.19 -0.4 5.23e-15 Longevity; LIHC cis rs600806 0.850 rs10776807 chr1:109956156 A/G cg08911820 chr1:110026001 ATXN7L2 0.61 7.73 0.39 1.2e-13 Intelligence (multi-trait analysis); LIHC cis rs10911251 0.546 rs7473 chr1:183114634 G/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.69 0.5 3.4e-23 Colorectal cancer; LIHC cis rs7412746 0.658 rs4970982 chr1:150865084 G/C cg15448220 chr1:150897856 SETDB1 0.44 6.97 0.35 1.64e-11 Melanoma; LIHC cis rs9322193 0.607 rs9383941 chr6:150233236 A/G cg01145232 chr6:150245071 RAET1G -0.37 -7.26 -0.37 2.62e-12 Lung cancer; LIHC cis rs8067545 0.750 rs36077949 chr17:19985782 C/T cg13482628 chr17:19912719 NA 0.49 8.1 0.4 9.75e-15 Schizophrenia; LIHC cis rs9303401 1.000 rs9303401 chr17:56847945 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.43 6.43 0.33 4.19e-10 Cognitive test performance; LIHC cis rs992157 0.764 rs10932774 chr2:219191569 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.64 9.01 0.44 1.52e-17 Colorectal cancer; LIHC cis rs12682352 0.602 rs1473029 chr8:8668917 A/C cg06636001 chr8:8085503 FLJ10661 0.43 6.62 0.34 1.4e-10 Neuroticism; LIHC cis rs2012796 0.704 rs57670850 chr14:81841577 C/T cg02996355 chr14:81879375 NA 0.77 12.44 0.56 1.41e-29 Night sleep phenotypes; LIHC cis rs78545713 0.649 rs11753717 chr6:26220202 G/C cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs1185460 1.000 rs1185460 chr11:118943433 C/T cg23280166 chr11:118938394 VPS11 -0.61 -8.05 -0.4 1.43e-14 Coronary artery disease; LIHC cis rs4800452 0.826 rs28625207 chr18:20746672 A/G cg26136497 chr18:20735537 CABLES1 -0.44 -5.72 -0.3 2.29e-8 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs1670533 0.932 rs4690214 chr4:1054636 T/C cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC trans rs1005277 0.579 rs2474571 chr10:38384639 T/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs600806 0.850 rs4970751 chr1:109896600 A/C cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs6598955 0.724 rs6656716 chr1:26563105 G/A cg04990556 chr1:26633338 UBXN11 -0.62 -10.18 -0.48 1.93e-21 Obesity-related traits; LIHC trans rs11098499 0.954 rs66506550 chr4:120371445 T/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs62179067 0.708 rs11903793 chr2:179934583 C/G cg27622325 chr2:179545785 TTN 0.58 5.77 0.3 1.82e-8 Late-onset Alzheimer's disease; LIHC cis rs7296418 0.961 rs11608811 chr12:123529056 A/G cg00376283 chr12:123451042 ABCB9 0.76 13.94 0.6 2.82e-35 Platelet count; LIHC cis rs2359239 0.519 rs8007145 chr14:75185748 T/A cg08847533 chr14:75593920 NEK9 0.51 7.88 0.39 4.49e-14 Neuroticism (multi-trait analysis); LIHC cis rs6570726 0.935 rs380433 chr6:145859601 A/T cg23711669 chr6:146136114 FBXO30 0.56 10.02 0.48 7.09e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs7412746 0.658 rs10888397 chr1:150886752 A/G cg17724175 chr1:150552817 MCL1 -0.42 -8.74 -0.43 1.04e-16 Melanoma; LIHC cis rs600806 0.821 rs3879447 chr1:109891403 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.33 -0.32 7.65e-10 Intelligence (multi-trait analysis); LIHC cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg02931644 chr1:25747376 RHCE 0.36 7.89 0.39 4.2e-14 Plateletcrit;Mean corpuscular volume; LIHC cis rs1552244 0.882 rs3732966 chr3:10015740 C/T cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs67311347 0.577 rs11129870 chr3:40260406 G/A cg10755058 chr3:40428713 ENTPD3 0.35 5.75 0.3 1.95e-8 Renal cell carcinoma; LIHC cis rs1494950 1.000 rs79999663 chr4:14974623 T/G cg12377275 chr4:15005593 CPEB2 -0.78 -6.57 -0.33 1.83e-10 Political ideology; LIHC cis rs10504229 0.679 rs72649120 chr8:58040308 C/T cg20607798 chr8:58055168 NA 0.46 6.3 0.32 9.07e-10 Developmental language disorder (linguistic errors); LIHC cis rs965469 0.671 rs6139076 chr20:3305210 T/C cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg21724239 chr8:58056113 NA 0.46 6.14 0.32 2.25e-9 Developmental language disorder (linguistic errors); LIHC cis rs2832191 0.791 rs4817270 chr21:30480368 G/A cg24692254 chr21:30365293 RNF160 -0.7 -12.91 -0.57 2.54e-31 Dental caries; LIHC cis rs7927771 1.000 rs10838757 chr11:47763016 T/C cg20135002 chr11:47629003 NA -0.53 -9.25 -0.45 2.54e-18 Subjective well-being; LIHC cis rs2933343 1.000 rs789237 chr3:128636961 A/C cg25356066 chr3:128598488 ACAD9 0.52 6.95 0.35 1.86e-11 IgG glycosylation; LIHC cis rs6912958 0.781 rs9444504 chr6:88181046 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.13 -0.36 6e-12 Monocyte percentage of white cells; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.61 -12.03 -0.55 4.8e-28 Prudent dietary pattern; LIHC cis rs7131987 0.903 rs10843371 chr12:29414232 G/A cg21522988 chr12:29376872 FAR2 0.28 6.42 0.33 4.61e-10 QT interval; LIHC trans rs11157436 0.874 rs35951144 chr14:22617926 G/C cg13567813 chr19:50879636 NR1H2 0.45 6.6 0.34 1.57e-10 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs72781680 0.611 rs55868657 chr2:24295385 G/A cg06627628 chr2:24431161 ITSN2 -0.65 -7.54 -0.38 4.39e-13 Lymphocyte counts; LIHC cis rs507080 0.922 rs471227 chr11:118564601 T/C cg04173919 chr11:118528438 PHLDB1 0.35 6.57 0.33 1.89e-10 Serum metabolite levels; LIHC cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg11062466 chr8:58055876 NA 0.49 6.67 0.34 1.04e-10 Developmental language disorder (linguistic errors); LIHC cis rs769267 0.896 rs7253807 chr19:19631444 A/T cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.42 0.37 9.14e-13 Tonsillectomy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07318050 chr1:233086124 C1orf57 0.47 7.39 0.37 1.17e-12 Pancreatic cancer; LIHC cis rs3540 0.597 rs1978149 chr15:91036976 A/G cg22089800 chr15:90895588 ZNF774 0.6 8.37 0.41 1.52e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs16958440 0.581 rs11082564 chr18:44659149 C/G cg17192377 chr18:44677553 HDHD2 0.51 6.36 0.33 6.31e-10 Sitting height ratio; LIHC cis rs8060686 0.641 rs79323429 chr16:68084594 A/G cg05110241 chr16:68378359 PRMT7 -0.6 -6.87 -0.35 2.96e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs6089829 0.925 rs4809270 chr20:61676709 C/A cg03213289 chr20:61660250 NA 0.52 8.85 0.43 4.69e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs6964587 0.967 rs7781221 chr7:91664645 A/G cg17063962 chr7:91808500 NA 1.02 19.65 0.73 4.62e-58 Breast cancer; LIHC cis rs17539620 0.624 rs111868524 chr6:154839960 G/C cg20019720 chr6:154832845 CNKSR3 0.4 5.79 0.3 1.61e-8 Lipoprotein (a) levels; LIHC cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg06108461 chr20:60628389 TAF4 -0.62 -8.13 -0.4 7.77e-15 Obesity-related traits; LIHC cis rs4631830 0.832 rs2843554 chr10:51523861 G/T cg20129853 chr10:51489980 NA -0.41 -8.96 -0.44 2.14e-17 Prostate-specific antigen levels; LIHC cis rs7412746 0.611 rs4970984 chr1:150887377 T/C cg18016565 chr1:150552671 MCL1 0.5 9.59 0.46 1.87e-19 Melanoma; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10860527 chr2:109403091 CCDC138 -0.59 -6.91 -0.35 2.39e-11 Systolic blood pressure; LIHC cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg11645453 chr3:52864694 ITIH4 0.21 5.71 0.3 2.43e-8 Bipolar disorder; LIHC trans rs10506458 0.915 rs56321182 chr12:63392023 C/T cg22491629 chr6:157744540 C6orf35 -0.61 -11.06 -0.51 1.69e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs614226 0.935 rs7956998 chr12:120994932 G/A cg01236616 chr12:121019343 POP5 1.26 18.82 0.71 9.63e-55 Type 1 diabetes nephropathy; LIHC cis rs459571 0.959 rs460888 chr9:136913123 C/G cg13789015 chr9:136890014 NCRNA00094 0.44 7.97 0.4 2.31e-14 Platelet distribution width; LIHC cis rs7917772 0.636 rs2249850 chr10:104512006 A/G cg22532475 chr10:104410764 TRIM8 -0.36 -6.21 -0.32 1.52e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs56235845 0.694 rs11748912 chr5:176765395 G/A cg17509989 chr5:176798049 RGS14 0.59 7.83 0.39 6.21e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs6831352 0.918 rs29001201 chr4:100053861 T/C cg12011299 chr4:100065546 ADH4 -0.61 -9.97 -0.47 1.02e-20 Alcohol dependence; LIHC cis rs12497850 0.829 rs12636030 chr3:49182237 A/G cg07636037 chr3:49044803 WDR6 0.88 15.14 0.63 5.21e-40 Parkinson's disease; LIHC cis rs7635838 0.617 rs347587 chr3:11287155 A/G cg00170343 chr3:11313890 ATG7 -0.57 -9.17 -0.44 4.49e-18 HDL cholesterol; LIHC cis rs10744422 1.000 rs2061101 chr12:123348925 C/A cg22842854 chr12:123319900 HIP1R -0.64 -7.64 -0.38 2.24e-13 Schizophrenia; LIHC cis rs6542838 0.580 rs1607256 chr2:99543444 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.52 -7.31 -0.37 1.96e-12 Fear of minor pain; LIHC cis rs1707322 0.963 rs4630155 chr1:46257110 G/C cg06784218 chr1:46089804 CCDC17 0.39 6.9 0.35 2.55e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3806843 0.868 rs2531349 chr5:140120953 G/A cg19875535 chr5:140030758 IK -0.37 -6.08 -0.31 3.14e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg14828511 chr1:107599125 PRMT6 0.42 6.07 0.31 3.32e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11122272 0.735 rs2790882 chr1:231532783 A/G cg06096015 chr1:231504339 EGLN1 -0.5 -9.34 -0.45 1.31e-18 Hemoglobin concentration; LIHC cis rs7904368 0.754 rs7091240 chr10:16855683 G/A cg23933602 chr10:16859644 RSU1 0.59 5.8 0.3 1.53e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs7959452 0.590 rs11177644 chr12:69785748 A/G cg19645103 chr12:69753606 YEATS4 -0.4 -5.89 -0.3 9.05e-9 Blood protein levels; LIHC cis rs61990749 0.544 rs2544567 chr14:78181739 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.62 10.32 0.49 6.7e-22 Fibroblast growth factor basic levels; LIHC cis rs9948 0.655 rs6751132 chr2:97405866 T/C cg01990225 chr2:97406019 LMAN2L -0.77 -6.44 -0.33 4.06e-10 Erectile dysfunction and prostate cancer treatment; LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg07159469 chr16:89355005 ANKRD11 -0.4 -6.13 -0.31 2.41e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs11711311 1.000 rs9811746 chr3:113515060 T/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.47 9.06 0.44 1.06e-17 IgG glycosylation; LIHC cis rs155076 1.000 rs261427 chr13:21860998 G/A cg11317459 chr13:21872234 NA -1.13 -13.08 -0.58 5.75e-32 White matter hyperintensity burden; LIHC cis rs3733346 0.553 rs6813110 chr4:942660 C/T cg23939001 chr4:940644 TMEM175 0.63 12.53 0.56 6.42e-30 Sjögren's syndrome; LIHC cis rs7927592 0.763 rs4340059 chr11:68362433 A/G cg16797656 chr11:68205561 LRP5 0.5 8.85 0.43 4.7e-17 Total body bone mineral density; LIHC cis rs1707322 1.000 rs946527 chr1:46485970 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.34 0.32 7.21e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7178375 1.000 rs12907055 chr15:31204294 C/G cg04373760 chr16:53404718 NA 0.61 7.97 0.4 2.38e-14 Hypertriglyceridemia; LIHC cis rs9522267 0.737 rs9522289 chr13:112232110 G/A cg10483660 chr13:112241077 NA -0.24 -6.14 -0.32 2.27e-9 Hepatitis; LIHC cis rs7551222 0.663 rs1563828 chr1:204516577 A/G cg20240347 chr1:204465584 NA -0.36 -7.66 -0.38 1.96e-13 Schizophrenia; LIHC trans rs2727020 0.567 rs1164687 chr11:49290669 G/A cg03929089 chr4:120376271 NA 0.68 10.14 0.48 2.6e-21 Coronary artery disease; LIHC cis rs7107174 1.000 rs1385600 chr11:77936166 C/T cg02023728 chr11:77925099 USP35 -0.46 -8.7 -0.43 1.42e-16 Testicular germ cell tumor; LIHC cis rs4684776 0.867 rs1499119 chr3:11333291 G/T cg00170343 chr3:11313890 ATG7 -0.53 -7.34 -0.37 1.53e-12 Small vessel stroke; LIHC trans rs1414896 0.692 rs3767316 chr1:95705053 C/T cg24483554 chr1:179544584 NPHS2 -0.25 -6.13 -0.31 2.41e-9 Non-alcoholic fatty liver disease histology (AST); LIHC cis rs7208859 0.673 rs55904046 chr17:29215391 G/A cg13385521 chr17:29058706 SUZ12P 0.82 7.93 0.39 3.19e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs11088226 0.681 rs74779447 chr21:33929013 G/A cg09050820 chr6:167586206 TCP10L2 0.84 13.25 0.58 1.21e-32 Gastritis; LIHC cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg26116260 chr4:7069785 GRPEL1 1.0 18.4 0.71 4.69e-53 Monocyte percentage of white cells; LIHC cis rs6964587 0.967 rs10279943 chr7:91587477 G/C cg17063962 chr7:91808500 NA 1.02 19.53 0.73 1.36e-57 Breast cancer; LIHC cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg00825309 chr19:58991885 ZNF446 0.55 8.96 0.44 2.07e-17 Uric acid clearance; LIHC cis rs733592 0.524 rs10875726 chr12:48425992 A/G cg21466736 chr12:48725269 NA 0.33 5.74 0.3 2.04e-8 Plateletcrit; LIHC trans rs7618501 1.000 rs7618519 chr3:49772708 A/T cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.967 rs4904663 chr14:90729565 G/T cg14092571 chr14:90743983 NA -0.41 -6.53 -0.33 2.34e-10 Mortality in heart failure; LIHC cis rs3820500 0.585 rs1289960 chr1:117926118 C/T cg20383390 chr1:117909022 MAN1A2 0.44 5.74 0.3 2.11e-8 Pneumonia; LIHC cis rs12220238 0.730 rs4746177 chr10:75913033 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.69 0.34 9.14e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs4631830 0.720 rs11599333 chr10:51499655 A/C cg16070123 chr10:51489643 NA 0.37 5.9 0.3 8.68e-9 Prostate-specific antigen levels; LIHC cis rs7582720 1.000 rs72934573 chr2:204005072 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs2710642 0.525 rs1601673 chr2:62842559 G/C cg23713900 chr18:615496 CLUL1 -0.24 -6.23 -0.32 1.4e-9 LDL cholesterol levels;LDL cholesterol; LIHC cis rs8081395 0.801 rs2665405 chr17:57875292 G/A cg02344993 chr17:57696989 CLTC -0.44 -7.19 -0.36 3.99e-12 White blood cell count; LIHC cis rs651907 0.535 rs17412601 chr3:101499275 T/C cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC trans rs2352908 1.000 rs12897476 chr14:49453299 G/T cg16568472 chr20:3190600 ITPA -0.45 -6.12 -0.31 2.55e-9 Social communication problems; LIHC cis rs1568889 0.838 rs10835299 chr11:28277693 A/G cg06544937 chr11:28130018 METT5D1;KIF18A -0.66 -13.88 -0.6 4.79e-35 Bipolar disorder; LIHC cis rs1448094 0.549 rs7297996 chr12:86235899 C/T cg02569458 chr12:86230093 RASSF9 0.49 6.49 0.33 2.95e-10 Major depressive disorder; LIHC cis rs875971 0.660 rs10229345 chr7:65982168 G/C cg18876405 chr7:65276391 NA 0.45 7.44 0.37 8.06e-13 Aortic root size; LIHC cis rs2153535 0.580 rs9328488 chr6:8529411 G/C cg07606381 chr6:8435919 SLC35B3 0.79 11.72 0.54 6.76e-27 Motion sickness; LIHC cis rs929354 0.772 rs1182441 chr7:157026650 A/G cg17757837 chr7:157058334 UBE3C -0.72 -11.73 -0.54 6.15e-27 Body mass index; LIHC cis rs9368481 0.761 rs4358615 chr6:26998567 A/G cg18867708 chr6:26865862 GUSBL1 0.57 8.88 0.43 3.93e-17 Autism spectrum disorder or schizophrenia; LIHC cis rs8103278 0.701 rs116959973 chr19:46252333 A/T cg14061069 chr19:46274453 DMPK -0.49 -7.15 -0.36 5.22e-12 Coronary artery disease; LIHC cis rs10493773 0.609 rs10873716 chr1:86178347 G/T cg17807903 chr1:86174739 ZNHIT6 -0.61 -11.93 -0.54 1.16e-27 Urate levels in overweight individuals; LIHC cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg20341384 chr10:131568735 NA -0.41 -6.27 -0.32 1.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg20887711 chr4:1340912 KIAA1530 -0.76 -11.04 -0.51 1.87e-24 Longevity; LIHC cis rs1008375 1.000 rs28501187 chr4:17643620 G/A cg02297831 chr4:17616191 MED28 0.51 7.96 0.4 2.49e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14047548 chr9:136199066 SURF6 0.44 7.0 0.35 1.36e-11 Longevity; LIHC cis rs1789 0.903 rs4470622 chr4:15674175 T/G cg21329975 chr4:15471214 CC2D2A -0.4 -5.87 -0.3 1.06e-8 Blood protein levels; LIHC cis rs875971 0.929 rs6970860 chr7:65976634 A/G cg18876405 chr7:65276391 NA 0.37 6.75 0.34 6.39e-11 Aortic root size; LIHC cis rs2845885 0.793 rs56241103 chr11:63882364 C/T cg05555928 chr11:63887634 MACROD1 -0.51 -7.07 -0.36 8.6e-12 Body mass index; LIHC cis rs611744 0.905 rs677031 chr8:109152068 G/A cg21045802 chr8:109455806 TTC35 0.48 8.12 0.4 8.4e-15 Dupuytren's disease; LIHC cis rs77633900 0.614 rs2439992 chr15:76863023 T/G cg21673338 chr15:77095150 SCAPER -0.49 -7.36 -0.37 1.42e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs2288073 1.000 rs2288073 chr2:24413298 C/T cg06627628 chr2:24431161 ITSN2 0.57 7.58 0.38 3.22e-13 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs10789491 1.000 rs11211342 chr1:47163098 T/C cg15501359 chr1:47185051 KIAA0494 0.77 11.16 0.52 7.08e-25 Response to hepatitis C treatment; LIHC cis rs3008870 1.000 rs2985818 chr1:67398916 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.44 0.66 3.6e-45 Lymphocyte percentage of white cells; LIHC cis rs1348850 0.914 rs12469386 chr2:178358281 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.83 -13.0 -0.58 1.14e-31 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs763121 0.925 rs5750654 chr22:39051428 T/C cg06022373 chr22:39101656 GTPBP1 0.72 14.5 0.62 1.76e-37 Menopause (age at onset); LIHC cis rs7091068 0.721 rs618951 chr10:95404967 A/G cg20715218 chr10:95462985 C10orf4 -0.6 -6.87 -0.35 3.04e-11 Urinary tract infection frequency; LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg24846343 chr22:24311635 DDTL 0.56 9.53 0.46 3.07e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1113500 0.932 rs1343205 chr1:108597873 C/G cg06207961 chr1:108661230 NA 0.36 7.05 0.36 1.02e-11 Growth-regulated protein alpha levels; LIHC cis rs9457247 0.905 rs377232 chr6:167409638 C/A cg23791538 chr6:167370224 RNASET2 -0.63 -10.63 -0.5 5.61e-23 Crohn's disease; LIHC cis rs2841277 0.708 rs4465542 chr14:105407798 A/G cg15352829 chr14:105391018 PLD4 -0.42 -9.08 -0.44 9.13e-18 Rheumatoid arthritis; LIHC cis rs7216064 1.000 rs62085993 chr17:65923152 T/C cg12091567 chr17:66097778 LOC651250 -0.61 -8.62 -0.42 2.61e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs12586317 0.547 rs74462850 chr14:35500093 G/T cg16230307 chr14:35515116 FAM177A1 0.78 13.24 0.58 1.39e-32 Psoriasis; LIHC cis rs7659604 0.539 rs7699776 chr4:122753885 A/G cg20573242 chr4:122745356 CCNA2 0.52 7.66 0.38 1.96e-13 Type 2 diabetes; LIHC cis rs507080 0.922 rs519848 chr11:118552715 G/A cg04173919 chr11:118528438 PHLDB1 0.32 5.99 0.31 5.4e-9 Serum metabolite levels; LIHC cis rs908922 0.676 rs11205032 chr1:152527690 A/G cg20991723 chr1:152506922 NA 0.57 10.02 0.48 7.07e-21 Hair morphology; LIHC cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.36 0.45 1.11e-18 Bipolar disorder; LIHC cis rs7312933 0.510 rs10880223 chr12:42413443 G/A cg17420585 chr12:42539391 GXYLT1 -0.54 -9.23 -0.45 2.8e-18 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7945705 0.870 rs1109305 chr11:8955272 C/T cg12365402 chr11:9010492 NRIP3 0.31 8.04 0.4 1.5e-14 Hemoglobin concentration; LIHC cis rs17685 0.796 rs3757594 chr7:75678644 G/A cg04592579 chr7:75616294 TMEM120A -0.39 -6.73 -0.34 7.3e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7917772 0.636 rs1475644 chr10:104491164 G/A cg22532475 chr10:104410764 TRIM8 -0.37 -6.67 -0.34 1.03e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2576037 0.501 rs557661 chr18:44365657 A/G cg19077165 chr18:44547161 KATNAL2 -0.42 -6.36 -0.33 6.28e-10 Personality dimensions; LIHC cis rs208520 0.754 rs851593 chr6:66875783 C/T cg07460842 chr6:66804631 NA 0.8 8.98 0.44 1.83e-17 Exhaled nitric oxide output; LIHC cis rs4665809 0.878 rs4665826 chr2:26367503 A/T cg04944784 chr2:26401820 FAM59B 0.72 9.24 0.45 2.74e-18 Gut microbiome composition (summer); LIHC cis rs8081395 0.801 rs12938273 chr17:57901652 G/A cg02344993 chr17:57696989 CLTC -0.46 -7.57 -0.38 3.41e-13 White blood cell count; LIHC cis rs8072100 0.748 rs9912592 chr17:45556945 G/A cg08085267 chr17:45401833 C17orf57 -0.44 -6.49 -0.33 2.93e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2073300 0.609 rs12625164 chr20:23354269 T/C cg12062639 chr20:23401060 NAPB 1.08 14.15 0.61 4.1e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4407350 0.901 rs5765717 chr22:44917646 G/T cg26276947 chr22:44892394 LDOC1L 0.34 6.4 0.33 4.99e-10 Intelligence (multi-trait analysis); LIHC cis rs986417 1.000 rs1116853 chr14:60917476 A/G cg27398547 chr14:60952738 C14orf39 0.74 8.46 0.42 7.95e-16 Gut microbiota (bacterial taxa); LIHC cis rs919433 0.679 rs67492914 chr2:198523402 T/G cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs6831352 0.734 rs1453872 chr4:100022482 G/A cg12011299 chr4:100065546 ADH4 0.56 9.89 0.47 1.84e-20 Alcohol dependence; LIHC cis rs6594499 0.542 rs4530809 chr5:110462230 A/G cg04022379 chr5:110408740 TSLP 0.52 8.41 0.41 1.14e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7677751 0.848 rs4635872 chr4:55099041 C/A cg17187183 chr4:55093834 PDGFRA 0.68 8.52 0.42 5.13e-16 Corneal astigmatism; LIHC cis rs7107174 0.901 rs7937277 chr11:78114977 C/G cg02023728 chr11:77925099 USP35 0.35 6.24 0.32 1.28e-9 Testicular germ cell tumor; LIHC cis rs2851682 0.706 rs2524299 chr11:61604782 A/T cg27386326 chr11:61587980 NA 0.57 9.23 0.45 2.89e-18 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs919433 1.000 rs1560277 chr2:198187903 C/T cg03934865 chr2:198174659 NA 0.56 8.81 0.43 6.23e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs116095464 0.558 rs7708182 chr5:234788 C/G cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.78e-52 Breast cancer; LIHC cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.1e-16 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg23758822 chr17:41437982 NA 0.94 17.94 0.7 3.44e-51 Menopause (age at onset); LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg12419862 chr22:24373484 LOC391322 -0.67 -9.84 -0.47 2.69e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4790333 0.529 rs3101409 chr17:2258147 C/T cg02569219 chr17:2266849 SGSM2 0.42 6.41 0.33 4.77e-10 Proinsulin levels; LIHC cis rs2952156 0.920 rs903502 chr17:37829604 C/T cg00129232 chr17:37814104 STARD3 -0.54 -10.07 -0.48 4.6e-21 Asthma; LIHC cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg02782426 chr3:40428986 ENTPD3 0.34 6.18 0.32 1.77e-9 Renal cell carcinoma; LIHC cis rs2439831 0.867 rs2264876 chr15:43757419 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.57 0.59 7.69e-34 Lung cancer in ever smokers; LIHC cis rs911119 0.955 rs6048933 chr20:23595637 T/G cg16589663 chr20:23618590 CST3 0.77 7.89 0.39 4.17e-14 Chronic kidney disease; LIHC trans rs7668874 0.821 rs1898879 chr4:116808018 G/A cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg02951883 chr7:2050386 MAD1L1 0.56 8.34 0.41 1.87e-15 Bipolar disorder and schizophrenia; LIHC cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs4975709 0.589 rs4975747 chr5:1862836 G/A cg14773178 chr5:1868261 NA 0.27 7.23 0.36 3.19e-12 Cardiovascular disease risk factors; LIHC cis rs6435862 0.636 rs717548 chr2:215676905 G/A cg04530015 chr2:215796436 ABCA12 0.48 8.98 0.44 1.85e-17 Neuroblastoma (high-risk); LIHC cis rs1003719 0.680 rs3737540 chr21:38523266 C/A cg10648535 chr21:38446584 PIGP;TTC3 -0.66 -9.99 -0.48 8.82e-21 Eye color traits; LIHC cis rs17286411 0.750 rs12444594 chr16:71941912 A/T cg06353428 chr16:71660113 MARVELD3 0.55 6.68 0.34 9.6e-11 Blood protein levels; LIHC cis rs4676482 0.796 rs4676609 chr3:39214256 C/T cg02254461 chr3:39195904 CSRNP1 0.63 6.92 0.35 2.17e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs4700695 0.841 rs251300 chr5:65299715 C/G cg21114390 chr5:65439923 SFRS12 -0.44 -5.76 -0.3 1.9e-8 Facial morphology (factor 19); LIHC cis rs4975616 0.714 rs27069 chr5:1347128 C/T cg07493874 chr5:1342172 CLPTM1L -0.62 -9.66 -0.46 1.13e-19 Lung cancer; LIHC cis rs7927592 0.763 rs7129248 chr11:68263276 A/T cg20283391 chr11:68216788 NA -0.37 -5.95 -0.31 6.65e-9 Total body bone mineral density; LIHC cis rs748404 0.697 rs530188 chr15:43545314 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.42 6.44 0.33 4.13e-10 Lung cancer; LIHC cis rs67311347 0.577 rs1880763 chr3:40283255 C/T cg13409248 chr3:40428643 ENTPD3 -0.42 -6.73 -0.34 7.27e-11 Renal cell carcinoma; LIHC cis rs8016982 0.633 rs4363794 chr14:81674327 C/A cg01989461 chr14:81687754 GTF2A1 0.63 12.7 0.57 1.59e-30 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07704136 chr3:110790533 PVRL3 0.42 6.12 0.31 2.55e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4906332 1.000 rs2065017 chr14:103879579 T/C cg26031613 chr14:104095156 KLC1 -0.4 -5.72 -0.3 2.31e-8 Coronary artery disease; LIHC cis rs6831352 0.819 rs2851274 chr4:100025866 G/C cg12011299 chr4:100065546 ADH4 0.55 9.89 0.47 1.82e-20 Alcohol dependence; LIHC cis rs9503598 0.605 rs9968900 chr6:3457687 C/T cg00476032 chr6:3446245 SLC22A23 0.41 7.86 0.39 5.11e-14 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs6964587 0.934 rs7811328 chr7:91720931 A/T cg17063962 chr7:91808500 NA 1.0 19.05 0.72 1.18e-55 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07881982 chr3:156878112 CCNL1 0.49 6.71 0.34 8.04e-11 Pancreatic cancer; LIHC cis rs8053891 0.673 rs10492824 chr16:72018771 A/C cg01557791 chr16:72042693 DHODH -0.5 -7.34 -0.37 1.53e-12 Coronary artery disease; LIHC cis rs9660992 0.547 rs748012 chr1:205216573 C/T cg21545522 chr1:205238299 TMCC2 0.36 6.86 0.35 3.19e-11 Mean corpuscular volume;Mean platelet volume; LIHC cis rs35110281 0.666 rs2236665 chr21:45108987 C/A cg04455712 chr21:45112962 RRP1B 0.54 9.25 0.45 2.44e-18 Mean corpuscular volume; LIHC cis rs4575098 0.626 rs11265557 chr1:161106354 T/G cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.4 7.4 0.37 1.03e-12 Monocyte percentage of white cells; LIHC cis rs2204008 0.582 rs11179135 chr12:38204689 A/C cg26384229 chr12:38710491 ALG10B 0.88 10.83 0.51 1.1e-23 Bladder cancer; LIHC trans rs116095464 0.558 rs10076655 chr5:239464 G/C cg00938859 chr5:1591904 SDHAP3 0.58 7.11 0.36 7.03e-12 Breast cancer; LIHC trans rs3780486 0.846 rs7036812 chr9:33143822 T/C cg20290983 chr6:43655470 MRPS18A 1.18 30.61 0.86 5.36e-100 IgG glycosylation; LIHC cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.38 -6.74 -0.34 6.89e-11 Total body bone mineral density; LIHC cis rs6867032 0.834 rs10043083 chr5:1995687 C/G cg26168224 chr5:2018326 NA -0.24 -6.0 -0.31 5.08e-9 Gut microbiome composition (winter); LIHC cis rs10463316 0.928 rs10060441 chr5:150750006 A/G cg03212797 chr5:150827313 SLC36A1 -0.41 -6.25 -0.32 1.23e-9 Metabolite levels (Pyroglutamine); LIHC cis rs172166 0.694 rs1631552 chr6:28089699 C/A cg16479474 chr6:28041457 NA 0.39 6.51 0.33 2.68e-10 Cardiac Troponin-T levels; LIHC cis rs7107174 0.892 rs10793310 chr11:78099014 T/G cg02023728 chr11:77925099 USP35 0.46 8.51 0.42 5.45e-16 Testicular germ cell tumor; LIHC cis rs4718428 1.000 rs4718428 chr7:66421446 T/G cg11764359 chr7:65958608 NA 0.49 6.56 0.33 2.02e-10 Corneal structure; LIHC cis rs2235642 0.750 rs1894649 chr16:1657284 C/G cg03034668 chr16:1723424 CRAMP1L -0.4 -7.08 -0.36 8.25e-12 Coronary artery disease; LIHC cis rs5769765 0.955 rs9616368 chr22:50303533 C/G cg02269571 chr22:50332266 NA -0.74 -9.76 -0.47 5.22e-20 Schizophrenia; LIHC cis rs526231 0.963 rs12187443 chr5:102660400 T/C cg05225461 chr5:102596755 C5orf30 0.37 5.74 0.3 2.13e-8 Primary biliary cholangitis; LIHC cis rs6570726 1.000 rs1935617 chr6:145943326 C/T cg23711669 chr6:146136114 FBXO30 0.49 8.52 0.42 5.29e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg23758822 chr17:41437982 NA 0.95 17.94 0.7 3.4e-51 Menopause (age at onset); LIHC cis rs950776 0.518 rs12914694 chr15:78814444 G/A cg06917634 chr15:78832804 PSMA4 0.92 13.72 0.6 1.9e-34 Sudden cardiac arrest; LIHC cis rs9300255 0.596 rs1727331 chr12:123718879 C/G cg00376283 chr12:123451042 ABCB9 -0.7 -10.61 -0.5 6.46e-23 Neutrophil percentage of white cells; LIHC cis rs875971 0.862 rs778724 chr7:65829291 T/C cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs427394 0.582 rs274665 chr5:6707981 C/T cg10857441 chr5:6722123 POLS -0.37 -6.33 -0.32 7.92e-10 Menopause (age at onset); LIHC cis rs4555082 0.957 rs2735818 chr14:105714751 A/G cg13114125 chr14:105738426 BRF1 -0.71 -9.56 -0.46 2.33e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs11955398 0.716 rs12514253 chr5:59998301 G/A cg02684056 chr5:59996105 DEPDC1B 0.4 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs969421 chr6:8451949 A/C cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC cis rs644799 1.000 rs568668 chr11:95528209 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.82 0.47 3.16e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6430585 0.528 rs16832417 chr2:136744678 C/T cg07169764 chr2:136633963 MCM6 1.28 21.06 0.75 1.03e-63 Corneal structure; LIHC cis rs3768617 0.811 rs12066082 chr1:183054863 G/C ch.1.3577855R chr1:183094577 LAMC1 0.48 7.69 0.38 1.62e-13 Fuchs's corneal dystrophy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03771185 chr4:775700 NA 0.43 6.27 0.32 1.11e-9 Pancreatic cancer; LIHC cis rs66573146 0.831 rs67665838 chr4:7064870 G/A cg19539972 chr4:7069911 GRPEL1 -0.69 -7.44 -0.37 8.36e-13 Granulocyte percentage of myeloid white cells; LIHC cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.54e-26 Alzheimer's disease; LIHC cis rs200895692 1 rs200895692 chr1:43421956 CGCCTGTAATCCCAG/C cg12656391 chr1:43425156 SLC2A1 -0.47 -6.22 -0.32 1.43e-9 Monocyte count; LIHC cis rs17685 0.712 rs7778735 chr7:75770237 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.84 0.63 8.46e-39 Prudent dietary pattern; LIHC cis rs9303401 0.659 rs12602389 chr17:56779778 G/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.65 0.42 2e-16 Cognitive test performance; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.56 0.62 1.09e-37 Prudent dietary pattern; LIHC cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.34 0.55 3.52e-29 Alzheimer's disease; LIHC cis rs7131987 0.621 rs6487805 chr12:29457550 A/T cg00204748 chr12:29376779 FAR2 -0.38 -7.08 -0.36 8.41e-12 QT interval; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg06873352 chr17:61820015 STRADA 0.71 12.16 0.55 1.68e-28 Prudent dietary pattern; LIHC cis rs9942416 0.533 rs12109251 chr5:75024240 C/A cg19683494 chr5:74908142 NA 0.58 6.25 0.32 1.2e-9 Age-related disease endophenotypes; LIHC cis rs240764 0.658 rs7746947 chr6:101188708 G/A cg09795085 chr6:101329169 ASCC3 -0.46 -6.69 -0.34 9.07e-11 Neuroticism; LIHC cis rs11958404 0.929 rs72816508 chr5:157356031 G/T cg05962755 chr5:157440814 NA 1.0 9.55 0.46 2.51e-19 IgG glycosylation; LIHC cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg11890956 chr21:40555474 PSMG1 1.03 15.13 0.63 6.21e-40 Cognitive function; LIHC cis rs4819052 1.000 rs2297284 chr21:46705345 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 10.06 0.48 4.9e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg21951975 chr1:209979733 IRF6 0.45 7.3 0.37 2.05e-12 Cleft lip with or without cleft palate; LIHC cis rs6503863 1 rs6503863 chr17:56517034 G/A cg12560992 chr17:57184187 TRIM37 0.78 12.57 0.56 4.77e-30 Intelligence (multi-trait analysis); LIHC cis rs7614311 0.731 rs6445387 chr3:63962678 C/G cg22134162 chr3:63841271 THOC7 -0.5 -6.19 -0.32 1.73e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs3770081 1.000 rs3770066 chr2:86392350 A/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.81 -8.97 -0.44 2.05e-17 Facial emotion recognition (sad faces); LIHC cis rs317689 0.918 rs689415 chr12:69738139 A/G cg14784868 chr12:69753453 YEATS4 -0.66 -9.9 -0.47 1.76e-20 Response to diuretic therapy; LIHC cis rs35306767 0.903 rs61833260 chr10:975148 T/G cg26597838 chr10:835615 NA 1.16 12.42 0.56 1.67e-29 Eosinophil percentage of granulocytes; LIHC cis rs4925386 1.000 rs2151512 chr20:60913495 T/C cg06026331 chr20:60912101 LAMA5 -0.5 -8.25 -0.41 3.41e-15 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2279817 0.818 rs34304724 chr1:17994850 C/T cg21791023 chr1:18019539 ARHGEF10L -0.72 -8.09 -0.4 1.07e-14 Neuroticism; LIHC cis rs68170813 0.559 rs6964966 chr7:106933099 C/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs6733011 0.508 rs12712041 chr2:99522059 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -6.87 -0.35 3.1e-11 Bipolar disorder; LIHC trans rs35365539 1 rs35365539 chr3:49794347 A/AC cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Blood protein levels; LIHC cis rs6504950 0.720 rs9910653 chr17:52992268 C/T cg10237252 chr17:52977213 TOM1L1 -0.36 -6.21 -0.32 1.57e-9 Breast cancer; LIHC cis rs2033908 0.620 rs10765993 chr11:12849185 C/G cg25843174 chr11:12811716 TEAD1 -0.32 -7.45 -0.37 7.71e-13 Sitting height ratio; LIHC cis rs7659604 0.539 rs3217771 chr4:122739483 G/A cg19748678 chr4:122722346 EXOSC9 0.66 10.97 0.51 3.37e-24 Type 2 diabetes; LIHC cis rs6545883 0.826 rs777591 chr2:61417617 A/G cg14146966 chr2:61757674 XPO1 0.41 6.77 0.34 5.6e-11 Tuberculosis; LIHC cis rs2952156 0.920 rs2934956 chr17:37830447 T/A cg00129232 chr17:37814104 STARD3 -0.54 -10.07 -0.48 4.6e-21 Asthma; LIHC cis rs8180040 0.900 rs10865946 chr3:47425060 T/G cg27129171 chr3:47204927 SETD2 0.56 9.49 0.46 4.12e-19 Colorectal cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg11223184 chr2:198033295 ANKRD44 -0.36 -6.19 -0.32 1.69e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs35306767 0.903 rs11253485 chr10:919362 C/T cg20503657 chr10:835505 NA 1.07 12.48 0.56 9.98e-30 Eosinophil percentage of granulocytes; LIHC cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs7618501 0.966 rs13063621 chr3:49821625 T/C cg21467203 chr3:49911342 NA -0.4 -6.93 -0.35 2.11e-11 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.716 rs2164101 chr15:76749117 A/G cg03037974 chr15:76606532 NA 0.8 16.45 0.66 3.21e-45 Blood metabolite levels; LIHC trans rs1552244 0.572 rs3894323 chr3:10168967 G/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg02990361 chr1:107599529 PRMT6 0.59 9.04 0.44 1.17e-17 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7487075 0.578 rs11183486 chr12:46837704 A/C cg23829395 chr12:46796953 NA 0.35 6.19 0.32 1.76e-9 Itch intensity from mosquito bite; LIHC trans rs913351 0.826 rs633858 chr9:129725493 A/G cg13692105 chr9:138592489 SOHLH1 0.39 6.07 0.31 3.36e-9 Lewy body disease; LIHC cis rs6684514 1.000 rs6684514 chr1:156255456 G/A cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7208859 0.623 rs1054397 chr17:29110196 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7487075 0.780 rs10785624 chr12:46766787 C/T cg15584813 chr12:47219626 SLC38A4 0.33 5.84 0.3 1.24e-8 Itch intensity from mosquito bite; LIHC cis rs986417 1.000 rs10130255 chr14:60944435 C/T cg27398547 chr14:60952738 C14orf39 0.81 9.28 0.45 1.97e-18 Gut microbiota (bacterial taxa); LIHC cis rs4423214 0.840 rs1792224 chr11:71176141 C/T cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC cis rs244293 1.000 rs244295 chr17:53242899 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.26 -0.37 2.66e-12 Menarche (age at onset); LIHC cis rs7312774 0.618 rs3759317 chr12:107370252 T/C cg16260113 chr12:107380972 MTERFD3 0.85 10.96 0.51 3.74e-24 Severe influenza A (H1N1) infection; LIHC cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.22e-8 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09311052 chr1:154531418 UBE2Q1 0.43 6.68 0.34 9.53e-11 Pancreatic cancer; LIHC trans rs12478296 0.792 rs6740738 chr2:243007368 A/C cg01596870 chr19:55963115 NA -0.65 -9.38 -0.45 9.71e-19 Obesity-related traits; LIHC cis rs7197653 0.667 rs7190070 chr16:68353983 C/T cg05110241 chr16:68378359 PRMT7 -0.93 -10.59 -0.5 7.37e-23 Magnesium levels; LIHC trans rs1945213 0.694 rs7131381 chr11:55858158 T/G cg03929089 chr4:120376271 NA 0.53 6.87 0.35 3.01e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg11494091 chr17:61959527 GH2 0.46 8.28 0.41 2.79e-15 Prudent dietary pattern; LIHC cis rs7572733 0.534 rs700670 chr2:198687284 T/C cg10820045 chr2:198174542 NA 0.45 6.82 0.35 4.18e-11 Dermatomyositis; LIHC cis rs6446731 0.734 rs9996868 chr4:3275484 C/T cg06533319 chr4:3265114 C4orf44 -0.34 -6.35 -0.32 6.93e-10 Mean platelet volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16139199 chr18:19180362 ESCO1 0.43 6.53 0.33 2.43e-10 Pancreatic cancer; LIHC cis rs4689592 0.523 rs6446565 chr4:7074027 A/G cg19539972 chr4:7069911 GRPEL1 0.69 10.02 0.48 7.08e-21 Monocyte percentage of white cells; LIHC cis rs7959452 0.649 rs4761239 chr12:69776886 T/A cg22834771 chr12:69754056 YEATS4 -0.51 -8.82 -0.43 5.86e-17 Blood protein levels; LIHC cis rs12477438 0.520 rs6708576 chr2:99801308 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.88 15.44 0.64 3.48e-41 Chronic sinus infection; LIHC cis rs13108904 0.901 rs13112706 chr4:1303682 G/T cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.21e-10 Obesity-related traits; LIHC cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg01017244 chr2:74357527 NA 0.62 11.17 0.52 6.85e-25 Gestational age at birth (maternal effect); LIHC cis rs12313068 0.656 rs41436646 chr12:110495171 C/G cg12870014 chr12:110450643 ANKRD13A 0.79 10.43 0.49 2.69e-22 Intelligence (multi-trait analysis); LIHC cis rs3762637 0.943 rs7629285 chr3:122265739 A/G cg24169773 chr3:122142474 KPNA1 0.41 8.38 0.41 1.38e-15 LDL cholesterol levels; LIHC cis rs2625529 0.730 rs2957368 chr15:72329906 C/T cg16672083 chr15:72433130 SENP8 -0.3 -5.78 -0.3 1.71e-8 Red blood cell count; LIHC cis rs875971 1.000 rs10257427 chr7:65743208 T/C cg18252515 chr7:66147081 NA 0.42 6.03 0.31 4.17e-9 Aortic root size; LIHC cis rs6912958 0.754 rs4707374 chr6:88255438 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.0 -0.4 1.94e-14 Monocyte percentage of white cells; LIHC cis rs10916814 0.546 rs10799643 chr1:20903181 G/C cg24502330 chr1:20914028 CDA -0.3 -6.62 -0.34 1.38e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7408868 0.764 rs12610803 chr19:15260682 A/C cg14696996 chr19:15285081 NOTCH3 0.48 6.24 0.32 1.28e-9 Pulse pressure; LIHC cis rs908922 0.676 rs478926 chr1:152511533 G/T cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC cis rs58688157 0.705 rs7943546 chr11:612148 T/C cg16486109 chr11:613632 IRF7 0.58 6.17 0.32 1.89e-9 Systemic lupus erythematosus; LIHC cis rs56104184 0.775 rs117744769 chr19:49402686 G/T cg21252483 chr19:49399788 TULP2 -1.06 -12.19 -0.55 1.27e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs4407350 0.721 rs3827402 chr22:44890651 T/C cg26276947 chr22:44892394 LDOC1L 0.34 6.43 0.33 4.31e-10 Intelligence (multi-trait analysis); LIHC cis rs116248771 0.739 rs73156496 chr3:158421162 T/C cg16708174 chr3:158430962 RARRES1 0.46 6.31 0.32 8.56e-10 diarrhoeal disease at age 2; LIHC cis rs8013055 0.846 rs8003942 chr14:105971670 A/G cg19700328 chr14:106028568 NA -0.35 -7.55 -0.38 3.91e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs2637266 1.000 rs2395386 chr10:78341623 C/T cg18941641 chr10:78392320 NA 0.3 6.41 0.33 4.95e-10 Pulmonary function; LIHC cis rs722599 0.683 rs8022046 chr14:75278302 G/A cg08847533 chr14:75593920 NEK9 0.54 8.24 0.41 3.59e-15 IgG glycosylation; LIHC trans rs11165623 0.564 rs11165658 chr1:96985670 A/G cg10631902 chr5:14652156 NA -0.3 -6.92 -0.35 2.24e-11 Hip circumference;Waist circumference; LIHC cis rs6840360 1.000 rs6535819 chr4:152651503 A/G cg22705602 chr4:152727874 NA -0.36 -7.74 -0.39 1.12e-13 Intelligence (multi-trait analysis); LIHC cis rs875971 0.830 rs6950137 chr7:65976610 G/A cg18876405 chr7:65276391 NA 0.35 6.45 0.33 3.86e-10 Aortic root size; LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg26338869 chr17:61819248 STRADA 0.52 6.94 0.35 1.98e-11 Height; LIHC cis rs79387448 0.745 rs7601773 chr2:103120483 G/T cg09003973 chr2:102972529 NA 0.81 7.09 0.36 7.59e-12 Gut microbiota (bacterial taxa); LIHC trans rs61931739 0.500 rs11053272 chr12:34547020 C/G cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs17106184 1.000 rs2175794 chr1:51333179 A/T cg07174182 chr1:51127561 FAF1 -0.62 -6.5 -0.33 2.91e-10 Type 2 diabetes; LIHC cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg13395646 chr4:1353034 KIAA1530 -0.66 -9.54 -0.46 2.84e-19 Obesity-related traits; LIHC cis rs12701220 0.948 rs12690826 chr7:1081618 A/G cg16145915 chr7:1198662 ZFAND2A -0.33 -6.37 -0.33 6.06e-10 Bronchopulmonary dysplasia; LIHC cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.2 -0.32 1.63e-9 Colorectal cancer; LIHC cis rs921968 0.544 rs58827325 chr2:219415166 A/T cg02176678 chr2:219576539 TTLL4 0.53 7.43 0.37 8.65e-13 Mean corpuscular hemoglobin concentration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21211866 chr9:35111727 KIAA1539 0.48 8.06 0.4 1.32e-14 Cognitive function; LIHC cis rs12478296 0.901 rs56318767 chr2:243046591 T/A cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.09e-27 Obesity-related traits; LIHC cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg08645402 chr16:4508243 NA 0.43 7.94 0.39 2.86e-14 Schizophrenia; LIHC cis rs1023500 0.505 rs134887 chr22:42674239 A/G cg04733989 chr22:42467013 NAGA 0.43 6.43 0.33 4.22e-10 Schizophrenia; LIHC cis rs507080 0.961 rs34413584 chr11:118545782 G/T cg04173919 chr11:118528438 PHLDB1 0.33 6.07 0.31 3.35e-9 Serum metabolite levels; LIHC cis rs875971 0.862 rs28470208 chr7:65584700 A/G cg18876405 chr7:65276391 NA -0.38 -6.74 -0.34 6.73e-11 Aortic root size; LIHC cis rs9858542 0.953 rs11713474 chr3:49611457 A/G cg03060546 chr3:49711283 APEH -0.52 -7.01 -0.35 1.25e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs11098499 0.863 rs1010740 chr4:120463409 C/T cg09307838 chr4:120376055 NA -0.77 -11.92 -0.54 1.27e-27 Corneal astigmatism; LIHC cis rs2075371 0.796 rs35440439 chr7:134006094 C/T cg20476274 chr7:133979776 SLC35B4 0.68 9.33 0.45 1.39e-18 Mean platelet volume; LIHC cis rs8180040 0.647 rs57756484 chr3:47239333 A/G cg16586182 chr3:47516702 SCAP 0.49 8.69 0.43 1.52e-16 Colorectal cancer; LIHC cis rs2412488 0.927 rs6833766 chr4:54312706 A/G cg22241045 chr4:54363911 LNX1 -0.42 -6.79 -0.34 4.97e-11 DNA methylation (variation); LIHC cis rs12824058 0.831 rs7979497 chr12:130804706 C/T cg26677194 chr12:130822605 PIWIL1 0.49 6.44 0.33 4.03e-10 Menopause (age at onset); LIHC trans rs2243480 0.522 rs1638736 chr7:66092308 A/T cg10756647 chr7:56101905 PSPH 1.08 11.93 0.54 1.13e-27 Diabetic kidney disease; LIHC cis rs858239 0.539 rs2178139 chr7:23191636 A/G cg23682824 chr7:23144976 KLHL7 0.46 6.83 0.35 3.89e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs1814175 0.650 rs6486000 chr11:49659090 T/A cg15704280 chr7:45808275 SEPT13 -0.93 -18.32 -0.7 1.02e-52 Height; LIHC cis rs9325144 0.560 rs10785573 chr12:38654166 G/A cg26384229 chr12:38710491 ALG10B -0.59 -8.11 -0.4 8.86e-15 Morning vs. evening chronotype; LIHC cis rs2806561 0.514 rs7414010 chr1:23543929 T/C cg19743168 chr1:23544995 NA 0.41 6.05 0.31 3.89e-9 Height; LIHC cis rs7267979 1.000 rs2474777 chr20:25272633 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.42 5.96 0.31 6.39e-9 Liver enzyme levels (alkaline phosphatase); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg23509745 chr3:184045221 EIF4G1 0.53 8.36 0.41 1.62e-15 Longevity; LIHC cis rs4900538 0.855 rs1209151 chr14:102893756 C/T cg18135206 chr14:102964638 TECPR2 -0.71 -10.96 -0.51 3.83e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg00587304 chr3:172468157 NA 0.37 6.28 0.32 1.01e-9 Metabolic traits; LIHC cis rs2072499 0.966 rs11587860 chr1:156156951 G/C cg24450063 chr1:156163899 SLC25A44 1.04 17.14 0.68 5.85e-48 Testicular germ cell tumor; LIHC cis rs10791097 0.748 rs2282579 chr11:130735482 C/T cg09137382 chr11:130731461 NA 0.4 5.99 0.31 5.19e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2404602 0.536 rs17364330 chr15:76765385 A/T cg03037974 chr15:76606532 NA 0.76 14.72 0.62 2.43e-38 Blood metabolite levels; LIHC cis rs59698941 0.943 rs67422135 chr5:132222728 T/A cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs6499255 0.951 rs8045705 chr16:69581672 A/G cg15192750 chr16:69999425 NA 0.49 7.41 0.37 1.03e-12 IgE levels; LIHC cis rs9486719 1.000 rs11153067 chr6:97039421 A/T cg06623918 chr6:96969491 KIAA0776 0.66 6.78 0.34 5.22e-11 Migraine;Coronary artery disease; LIHC cis rs8062405 0.755 rs111693583 chr16:28583610 C/T cg16576597 chr16:28551801 NUPR1 0.47 7.31 0.37 1.89e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11031096 0.502 rs4910598 chr11:4101368 C/T cg18678763 chr11:4115507 RRM1 -0.59 -8.74 -0.43 1.09e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9560113 1.000 rs11069895 chr13:112178824 C/T cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs36051895 0.632 rs7469563 chr9:5139489 C/T cg02405213 chr9:5042618 JAK2 -0.66 -11.66 -0.53 1.12e-26 Pediatric autoimmune diseases; LIHC cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg16434002 chr17:42200994 HDAC5 -0.52 -7.64 -0.38 2.25e-13 Total body bone mineral density; LIHC cis rs1577917 1.000 rs12212733 chr6:86726013 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.15 -0.48 2.39e-21 Response to antipsychotic treatment; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg23782820 chr8:58130467 NA 0.33 5.98 0.31 5.72e-9 Developmental language disorder (linguistic errors); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17400366 chr19:10420311 ZGLP1 0.42 6.46 0.33 3.54e-10 Alopecia areata; LIHC cis rs67311347 1.000 rs6762997 chr3:40478151 C/T cg24209194 chr3:40518798 ZNF619 0.46 6.84 0.35 3.57e-11 Renal cell carcinoma; LIHC cis rs11608355 0.545 rs12819658 chr12:109907670 A/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs473651 0.935 rs1103770 chr2:239339281 G/C cg18131467 chr2:239335373 ASB1 0.79 12.23 0.55 9.12e-29 Multiple system atrophy; LIHC cis rs10089 0.953 rs17164427 chr5:127361736 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.54 -6.83 -0.35 3.99e-11 Ileal carcinoids; LIHC cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg09323728 chr8:95962352 TP53INP1 -0.35 -7.8 -0.39 7.55e-14 Type 2 diabetes; LIHC cis rs7845219 0.539 rs713113 chr8:95877787 C/T cg13393036 chr8:95962371 TP53INP1 0.37 8.0 0.4 2e-14 Type 2 diabetes; LIHC cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg16606324 chr3:10149918 C3orf24 0.55 5.94 0.31 6.94e-9 Alzheimer's disease; LIHC cis rs5769765 0.671 rs138841 chr22:50181960 C/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.52 -6.33 -0.32 7.62e-10 Schizophrenia; LIHC cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11785693 0.862 rs7009771 chr8:4990189 C/T cg26367366 chr8:4980734 NA 0.55 5.94 0.31 6.87e-9 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs9905704 0.647 rs11659035 chr17:56966052 C/T cg12560992 chr17:57184187 TRIM37 0.68 9.97 0.47 9.92e-21 Testicular germ cell tumor; LIHC cis rs7937682 0.774 rs59921976 chr11:111473088 G/A cg22437258 chr11:111473054 SIK2 0.51 5.72 0.3 2.32e-8 Primary sclerosing cholangitis; LIHC cis rs6545883 0.965 rs766447 chr2:61735569 C/T cg14146966 chr2:61757674 XPO1 0.49 8.81 0.43 6.32e-17 Tuberculosis; LIHC cis rs6831352 0.734 rs12502237 chr4:100015675 G/A cg12011299 chr4:100065546 ADH4 0.56 9.89 0.47 1.84e-20 Alcohol dependence; LIHC cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg09323728 chr8:95962352 TP53INP1 -0.29 -6.07 -0.31 3.43e-9 Type 2 diabetes; LIHC cis rs2180341 1.000 rs6569479 chr6:127606588 A/G cg27446573 chr6:127587934 RNF146 1.01 15.75 0.65 2.03e-42 Breast cancer; LIHC cis rs9911578 0.681 rs8070135 chr17:56459063 G/A cg05425664 chr17:57184151 TRIM37 0.51 6.89 0.35 2.61e-11 Intelligence (multi-trait analysis); LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg01655898 chr14:21439243 NA -0.39 -6.28 -0.32 1.02e-9 Eotaxin levels; LIHC cis rs4665809 1.000 rs11126364 chr2:26314515 A/G cg27170947 chr2:26402098 FAM59B -0.62 -7.72 -0.39 1.27e-13 Gut microbiome composition (summer); LIHC cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC cis rs8180040 0.764 rs12629262 chr3:47196580 C/T cg02527881 chr3:46936655 PTH1R -0.32 -6.33 -0.32 7.83e-10 Colorectal cancer; LIHC cis rs9399135 0.967 rs9389256 chr6:135331254 A/C cg24558204 chr6:135376177 HBS1L 0.4 6.63 0.34 1.29e-10 Red blood cell count; LIHC cis rs2302190 0.882 rs7209650 chr17:56674905 C/T cg12560992 chr17:57184187 TRIM37 0.69 8.81 0.43 6.18e-17 Vitamin D levels; LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg18402987 chr7:1209562 NA 0.41 5.77 0.3 1.79e-8 Longevity;Endometriosis; LIHC trans rs783540 0.843 rs28374463 chr15:83299364 A/C cg18393722 chr15:85113863 UBE2QP1 -0.39 -6.77 -0.34 5.62e-11 Schizophrenia; LIHC cis rs9467773 0.595 rs2237236 chr6:26451553 A/G cg09904177 chr6:26538194 HMGN4 -0.35 -5.87 -0.3 1.01e-8 Intelligence (multi-trait analysis); LIHC cis rs7729447 0.566 rs3792765 chr5:32713836 A/G cg16267343 chr5:32710456 NPR3 0.48 6.1 0.31 2.9e-9 Blood pressure; LIHC cis rs9814567 1.000 rs13059720 chr3:134242021 T/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4474465 0.920 rs12271198 chr11:78158943 G/A cg02023728 chr11:77925099 USP35 0.34 6.11 0.31 2.67e-9 Alzheimer's disease (survival time); LIHC cis rs2019216 0.934 rs7405575 chr17:21936954 T/C cg22648282 chr17:21454238 C17orf51 -0.34 -5.71 -0.3 2.44e-8 Pelvic organ prolapse; LIHC cis rs4853012 0.838 rs2177707 chr2:74356850 A/G cg01017244 chr2:74357527 NA 0.65 11.76 0.54 4.66e-27 Gestational age at birth (maternal effect); LIHC cis rs6951245 0.554 rs11761322 chr7:1151657 A/G cg04025307 chr7:1156635 C7orf50 0.63 6.32 0.32 8.18e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 22.52 0.77 1.55e-69 Prudent dietary pattern; LIHC cis rs11626933 1.000 rs59905513 chr14:90749638 T/C cg04374321 chr14:90722782 PSMC1 0.47 6.5 0.33 2.85e-10 Gut microbiota (bacterial taxa); LIHC cis rs6430585 0.583 rs6728946 chr2:136635343 C/G cg15123519 chr2:136567270 LCT -0.38 -6.09 -0.31 3.03e-9 Corneal structure; LIHC cis rs6942756 1.000 rs7780886 chr7:128879347 G/A cg02491457 chr7:128862824 NA -0.73 -11.49 -0.53 4.78e-26 White matter hyperintensity burden; LIHC cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg03034668 chr16:1723424 CRAMP1L -0.34 -5.82 -0.3 1.32e-8 Coronary artery disease; LIHC cis rs11628318 0.515 rs12433517 chr14:103126912 T/G cg12046867 chr14:103022105 NA 0.39 5.92 0.3 7.82e-9 Platelet count; LIHC cis rs4638749 0.677 rs9631035 chr2:108818916 C/T cg06795125 chr2:108905320 SULT1C2 -0.31 -6.04 -0.31 3.92e-9 Blood pressure; LIHC cis rs12477438 0.520 rs2516827 chr2:99772565 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.82 0.65 1.12e-42 Chronic sinus infection; LIHC trans rs11098499 0.954 rs12510138 chr4:120423935 C/G cg25214090 chr10:38739885 LOC399744 0.56 9.24 0.45 2.72e-18 Corneal astigmatism; LIHC cis rs2576037 0.901 rs2576036 chr18:44587102 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.5 7.54 0.38 4.2e-13 Personality dimensions; LIHC trans rs208515 0.556 rs12206707 chr6:66697182 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.83 0.43 5.71e-17 Exhaled nitric oxide levels; LIHC cis rs4819052 0.851 rs4819041 chr21:46659955 C/T cg11663144 chr21:46675770 NA -0.32 -5.97 -0.31 6.01e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg00684032 chr4:1343700 KIAA1530 0.5 7.63 0.38 2.43e-13 Obesity-related traits; LIHC cis rs8017423 0.967 rs7155315 chr14:90700787 G/A cg14092571 chr14:90743983 NA -0.37 -5.8 -0.3 1.53e-8 Mortality in heart failure; LIHC cis rs7617773 0.779 rs9833309 chr3:48327450 C/T cg11946769 chr3:48343235 NME6 0.87 11.32 0.52 1.96e-25 Coronary artery disease; LIHC cis rs6456156 0.586 rs7761977 chr6:167485678 A/G cg12798992 chr6:167411361 FGFR1OP 0.44 6.65 0.34 1.13e-10 Primary biliary cholangitis; LIHC cis rs4845570 1.000 rs7416415 chr1:151757798 C/T cg07092448 chr1:151763213 TDRKH 0.69 7.78 0.39 8.61e-14 Coronary artery disease; LIHC cis rs2404602 0.647 rs12910081 chr15:77022959 G/C cg23625390 chr15:77176239 SCAPER -0.55 -9.23 -0.45 2.94e-18 Blood metabolite levels; LIHC cis rs875971 0.508 rs10950045 chr7:66066373 T/C cg18876405 chr7:65276391 NA -0.41 -7.34 -0.37 1.58e-12 Aortic root size; LIHC cis rs6088580 0.634 rs945673 chr20:32964265 C/A cg08999081 chr20:33150536 PIGU -0.67 -13.4 -0.59 3.26e-33 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01123282 chr2:157189755 NR4A2 -0.4 -6.07 -0.31 3.48e-9 Pancreatic cancer; LIHC cis rs9858542 0.953 rs1987628 chr3:49399259 G/A cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs801193 0.636 rs2659895 chr7:66196471 C/A cg10756647 chr7:56101905 PSPH 0.46 6.93 0.35 2.1e-11 Aortic root size; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05412136 chr9:36191352 CLTA 0.38 6.2 0.32 1.64e-9 Cognitive function; LIHC cis rs7715806 0.500 rs2307115 chr5:74990348 T/C cg19683494 chr5:74908142 NA 0.69 7.88 0.39 4.45e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9910055 0.530 rs2269907 chr17:42294215 G/A cg19774624 chr17:42201019 HDAC5 -0.56 -7.86 -0.39 5.16e-14 Total body bone mineral density; LIHC cis rs3849570 0.961 rs11710970 chr3:81693489 T/C cg07356753 chr3:81810745 GBE1 -0.63 -10.2 -0.48 1.71e-21 Waist circumference;Body mass index; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.08 -0.31 3.3e-9 Menopause (age at onset); LIHC cis rs2933343 0.716 rs9867404 chr3:128566138 A/G cg25356066 chr3:128598488 ACAD9 -0.52 -6.82 -0.35 4.11e-11 IgG glycosylation; LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg07167872 chr1:205819463 PM20D1 0.6 8.75 0.43 1.02e-16 Menarche (age at onset); LIHC cis rs17253792 0.822 rs77761669 chr14:56034216 G/A cg24579896 chr14:56047964 C14orf33;KTN1 0.73 6.03 0.31 4.36e-9 Putamen volume; LIHC trans rs11098499 0.863 rs3822191 chr4:120428101 A/T cg25214090 chr10:38739885 LOC399744 0.59 9.4 0.45 8.36e-19 Corneal astigmatism; LIHC cis rs7945705 0.902 rs2012696 chr11:8995818 A/C cg21881798 chr11:8931708 C11orf17;ST5 0.39 6.39 0.33 5.46e-10 Hemoglobin concentration; LIHC cis rs2806561 0.929 rs6660880 chr1:23540302 T/C cg19743168 chr1:23544995 NA -0.4 -7.52 -0.38 4.77e-13 Height; LIHC cis rs3768617 0.510 rs20558 chr1:183094547 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs11122272 0.735 rs2790891 chr1:231513190 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs6783573 1.000 rs6783573 chr3:46600520 A/G cg21489266 chr3:46619131 LRRC2;TDGF1 -0.4 -5.97 -0.31 6.04e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs36051895 0.593 rs62541903 chr9:5146952 G/C cg02405213 chr9:5042618 JAK2 -0.65 -10.99 -0.51 3.01e-24 Pediatric autoimmune diseases; LIHC cis rs10464366 0.614 rs62442213 chr7:39146933 C/T cg18850127 chr7:39170497 POU6F2 0.46 8.2 0.41 4.79e-15 IgG glycosylation; LIHC cis rs861318 0.640 rs3768514 chr1:159010309 A/G cg11003133 chr1:159046391 AIM2 -0.35 -6.66 -0.34 1.07e-10 Obesity-related traits; LIHC cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg05025164 chr4:1340916 KIAA1530 0.74 11.09 0.51 1.24e-24 Longevity; LIHC cis rs17685 0.725 rs7795291 chr7:75725206 C/A cg16684958 chr7:75615977 POR 0.51 8.49 0.42 6.51e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2153535 0.580 rs6912374 chr6:8456423 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs8180040 0.932 rs62248599 chr3:47516728 G/A cg16586182 chr3:47516702 SCAP 0.61 11.96 0.54 8.96e-28 Colorectal cancer; LIHC cis rs6461049 0.800 rs3778977 chr7:2159746 C/T cg04267008 chr7:1944627 MAD1L1 -0.48 -7.47 -0.37 6.83e-13 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04628465 chr16:85015467 ZDHHC7 -0.43 -6.28 -0.32 1.04e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8027181 0.682 rs890354 chr15:73100924 C/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.43 6.73 0.34 7.07e-11 Triglyceride levels; LIHC cis rs2439831 1.000 rs1814538 chr15:43759774 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.62 -8.68 -0.42 1.69e-16 Lung cancer in ever smokers; LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC cis rs798554 0.567 rs1182192 chr7:2869274 G/A cg19717773 chr7:2847554 GNA12 -0.43 -7.46 -0.37 7.27e-13 Height; LIHC cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg17971929 chr21:40555470 PSMG1 0.8 9.65 0.46 1.16e-19 Cognitive function; LIHC cis rs4908768 0.906 rs12122851 chr1:8634290 A/G cg20416874 chr1:8611966 RERE -0.57 -9.2 -0.45 3.63e-18 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2841277 0.708 rs9671643 chr14:105408030 A/G cg21017887 chr14:105400489 NA 0.66 12.86 0.57 3.7e-31 Rheumatoid arthritis; LIHC cis rs4407350 1.000 rs5765724 chr22:44921575 G/C cg26276947 chr22:44892394 LDOC1L 0.34 6.32 0.32 8.2e-10 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg07677032 chr17:61819896 STRADA 0.43 6.19 0.32 1.77e-9 Prudent dietary pattern; LIHC cis rs72627123 0.656 rs17096208 chr14:74555269 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.86 8.36 0.41 1.65e-15 Morning vs. evening chronotype; LIHC cis rs9768139 0.733 rs13221388 chr7:158119270 G/A cg25566285 chr7:158114605 PTPRN2 0.22 6.07 0.31 3.42e-9 Calcium levels; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs9814567 1.000 rs4309773 chr3:134277301 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1034435 0.547 rs5768686 chr22:48899214 G/A cg05992904 chr22:48892994 FAM19A5 -0.46 -8.33 -0.41 2.04e-15 Late-onset Alzheimer's disease; LIHC trans rs1814175 0.616 rs10839349 chr11:49753748 C/A cg15704280 chr7:45808275 SEPT13 -0.97 -20.39 -0.74 4.73e-61 Height; LIHC cis rs7619427 0.544 rs9872382 chr3:44021964 C/A cg24966902 chr3:44043705 NA 0.52 7.98 0.4 2.25e-14 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09379601 chr19:12992224 DNASE2 0.45 6.7 0.34 8.83e-11 Pancreatic cancer; LIHC trans rs12478296 0.786 rs6721704 chr2:242994923 A/G cg01596870 chr19:55963115 NA -0.65 -9.51 -0.46 3.63e-19 Obesity-related traits; LIHC cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs6951245 0.529 rs76001997 chr7:1152615 C/T cg04025307 chr7:1156635 C7orf50 0.62 6.15 0.32 2.16e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9534288 0.740 rs7989892 chr13:46630641 C/T cg15192986 chr13:46630673 CPB2 -0.6 -8.9 -0.43 3.41e-17 Blood protein levels; LIHC cis rs988712 0.622 rs10767664 chr11:27725986 T/A cg18117895 chr11:27722066 BDNF -0.49 -6.85 -0.35 3.39e-11 Obesity; LIHC cis rs6912958 0.781 rs9444519 chr6:88290398 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC cis rs11112613 0.609 rs7966960 chr12:106032152 G/A cg03607813 chr12:105948248 NA 0.42 6.59 0.34 1.64e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs614226 0.935 rs17431717 chr12:120912210 G/A cg01236616 chr12:121019343 POP5 -1.08 -11.22 -0.52 4.43e-25 Type 1 diabetes nephropathy; LIHC cis rs853679 0.769 rs7752448 chr6:28301099 A/G cg01086810 chr6:28234912 ZNF187 0.65 5.72 0.3 2.28e-8 Depression; LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs7666738 0.830 rs9995370 chr4:98732145 T/G cg05340658 chr4:99064831 C4orf37 0.64 11.59 0.53 2.03e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2574704 0.851 rs2574720 chr3:11660412 A/C cg15876825 chr3:11651881 VGLL4 0.45 7.08 0.36 8.46e-12 Body mass index; LIHC cis rs427394 0.802 rs200841 chr5:6737134 A/G cg10857441 chr5:6722123 POLS -0.36 -6.23 -0.32 1.4e-9 Menopause (age at onset); LIHC cis rs11252926 0.674 rs11598550 chr10:504778 A/C cg16346588 chr10:242978 ZMYND11 -0.39 -6.08 -0.31 3.13e-9 Psychosis in Alzheimer's disease; LIHC cis rs35306767 0.903 rs12778891 chr10:950130 T/A cg20503657 chr10:835505 NA 1.04 12.38 0.56 2.36e-29 Eosinophil percentage of granulocytes; LIHC cis rs1577917 0.637 rs1838957 chr6:86565056 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.47 -0.37 6.61e-13 Response to antipsychotic treatment; LIHC cis rs4474465 1.000 rs11237499 chr11:78163164 A/T cg02023728 chr11:77925099 USP35 0.33 6.01 0.31 4.82e-9 Alzheimer's disease (survival time); LIHC cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg05025164 chr4:1340916 KIAA1530 0.42 6.07 0.31 3.32e-9 Longevity; LIHC cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg05368731 chr17:41323189 NBR1 0.73 12.63 0.56 2.82e-30 Menopause (age at onset); LIHC cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs7212590 0.748 rs7220187 chr17:57897609 C/T cg10252138 chr17:58120427 NA -0.62 -6.11 -0.31 2.78e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs7635838 0.654 rs4684766 chr3:11285474 G/A cg00170343 chr3:11313890 ATG7 0.54 8.16 0.4 6.57e-15 HDL cholesterol; LIHC cis rs9814567 1.000 rs6782563 chr3:134295959 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.41 0.56 1.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05061393 chr2:220043337 FAM134A -0.45 -6.8 -0.35 4.77e-11 Cognitive function; LIHC cis rs903552 0.736 rs2412008 chr15:102006841 C/T cg19295451 chr15:102010161 PCSK6 -0.54 -7.53 -0.38 4.68e-13 Diabetic kidney disease; LIHC cis rs6089584 0.528 rs4925334 chr20:60626769 C/T cg23262073 chr20:60523788 NA -0.28 -5.78 -0.3 1.65e-8 Body mass index; LIHC cis rs6748734 1.000 rs6748734 chr2:241837452 A/G cg04034577 chr2:241836375 C2orf54 -0.42 -8.18 -0.4 5.48e-15 Urinary metabolites; LIHC cis rs7131987 0.650 rs11050208 chr12:29510369 T/G cg12903224 chr12:29470962 FAR2 -0.4 -6.21 -0.32 1.51e-9 QT interval; LIHC trans rs2832077 0.527 rs2250141 chr21:30241984 A/T cg14791747 chr16:20752902 THUMPD1 -0.66 -10.34 -0.49 5.69e-22 Cognitive test performance; LIHC cis rs8073060 0.519 rs8065286 chr17:33864479 A/G cg08516792 chr17:33866067 SLFN12L -0.38 -6.98 -0.35 1.57e-11 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs637571 0.522 rs11227368 chr11:65740370 C/T cg17712092 chr4:129076599 LARP1B 0.74 12.74 0.57 1.11e-30 Eosinophil percentage of white cells; LIHC cis rs600806 0.778 rs891379 chr1:110003605 A/G cg23091122 chr1:110024289 SYPL2 -0.5 -6.38 -0.33 5.72e-10 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.555 rs7965311 chr12:38513307 G/A cg26384229 chr12:38710491 ALG10B -0.67 -9.88 -0.47 2.01e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs3736485 0.966 rs11070859 chr15:51890802 C/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.66e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4423214 1.000 rs12419334 chr11:71139472 T/C cg05163923 chr11:71159392 DHCR7 0.91 14.5 0.62 1.76e-37 Vitamin D levels; LIHC trans rs11098499 0.774 rs11098505 chr4:120284627 C/T cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg20891558 chr2:74357851 NA 0.83 16.99 0.68 2.23e-47 Gestational age at birth (maternal effect); LIHC cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg20607798 chr8:58055168 NA 0.5 6.29 0.32 9.8e-10 Developmental language disorder (linguistic errors); LIHC cis rs2573652 0.722 rs8034841 chr15:100541593 G/T cg09918751 chr15:100517450 ADAMTS17 -0.72 -12.89 -0.57 2.99e-31 Height; LIHC cis rs8062405 1.000 rs7205323 chr16:28865892 C/T cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs34779708 0.966 rs7913615 chr10:35422957 T/G cg03585969 chr10:35415529 CREM 0.86 12.98 0.57 1.3e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9309473 0.904 rs79145598 chr2:73821382 T/A cg20560298 chr2:73613845 ALMS1 -0.55 -6.52 -0.33 2.59e-10 Metabolite levels; LIHC cis rs870825 0.616 rs2003994 chr4:185636568 G/T cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg13047869 chr3:10149882 C3orf24 0.53 6.86 0.35 3.24e-11 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05573182 chr20:39318437 MAFB 0.4 6.48 0.33 3.16e-10 Cognitive function; LIHC cis rs763121 0.853 rs8142098 chr22:39058757 T/G cg06022373 chr22:39101656 GTPBP1 0.66 11.49 0.53 4.72e-26 Menopause (age at onset); LIHC cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg06453172 chr10:134556979 INPP5A -0.64 -8.36 -0.41 1.64e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12701220 0.541 rs12535516 chr7:1114440 C/G cg26769984 chr7:1090371 C7orf50 0.58 5.91 0.3 8.17e-9 Bronchopulmonary dysplasia; LIHC cis rs11229555 0.645 rs11229427 chr11:58180275 A/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9733 0.596 rs72702585 chr1:150696427 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.87 -0.3 1.03e-8 Tonsillectomy; LIHC cis rs11671005 0.568 rs73068325 chr19:59079096 C/T cg25952890 chr19:58913133 NA 0.68 6.88 0.35 2.81e-11 Mean platelet volume; LIHC cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg08888203 chr3:10149979 C3orf24 0.53 6.43 0.33 4.35e-10 Alzheimer's disease; LIHC cis rs9902453 0.904 rs9905638 chr17:28261022 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.99 0.6 1.73e-35 Coffee consumption (cups per day); LIHC cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg04772025 chr11:68637568 NA 0.45 5.71 0.3 2.42e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs3749237 1.000 rs11920900 chr3:49823024 G/C cg21659725 chr3:3221576 CRBN 0.8 12.39 0.56 2.21e-29 Resting heart rate; LIHC cis rs1997103 1.000 rs6973337 chr7:55411534 T/C cg17469321 chr7:55412551 NA 0.5 7.24 0.36 3.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg00035636 chr13:21900591 NA 0.4 6.8 0.35 4.57e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs40363 0.645 rs6501177 chr16:3523681 C/T cg00484396 chr16:3507460 NAT15 0.44 7.8 0.39 7.35e-14 Tuberculosis; LIHC cis rs7618501 0.633 rs9814664 chr3:50078541 C/T cg24110177 chr3:50126178 RBM5 0.49 8.02 0.4 1.73e-14 Intelligence (multi-trait analysis); LIHC trans rs35110281 1.000 rs35110281 chr21:45068947 T/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.16 0.32 2.02e-9 Mean corpuscular volume; LIHC cis rs8062405 1.000 rs62036620 chr16:28833097 A/G cg00204512 chr16:28754710 NA 0.35 6.4 0.33 4.98e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2840044 1.000 rs2840044 chr17:33892068 A/G cg20932281 chr17:33905541 PEX12 0.42 5.87 0.3 1.01e-8 Response to radiotherapy in cancer (late toxicity); LIHC cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg18305652 chr10:134549665 INPP5A 0.51 7.95 0.39 2.82e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs7903847 0.642 rs10882910 chr10:99138043 G/A cg20016023 chr10:99160130 RRP12 -0.42 -6.51 -0.33 2.65e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs7980799 0.716 rs1351683 chr12:33598563 G/A cg26384229 chr12:38710491 ALG10B -0.45 -6.04 -0.31 4.11e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs7727544 0.904 rs7736102 chr5:131604257 G/A cg24060327 chr5:131705240 SLC22A5 -0.52 -5.83 -0.3 1.25e-8 Blood metabolite levels; LIHC cis rs11190604 1.000 rs4604805 chr10:102261409 C/G cg07080220 chr10:102295463 HIF1AN 0.58 8.59 0.42 3.04e-16 Palmitoleic acid (16:1n-7) levels; LIHC cis rs13118159 0.778 rs12640984 chr4:1338834 G/A cg16405210 chr4:1374714 KIAA1530 -0.5 -6.35 -0.32 6.67e-10 Longevity; LIHC cis rs3806843 0.932 rs2563256 chr5:140141779 G/T cg26395211 chr5:140044315 WDR55 0.4 5.97 0.31 5.79e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2204008 0.744 rs11514358 chr12:38255526 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs34779708 0.966 rs35146199 chr10:35460939 T/C cg04310649 chr10:35416472 CREM -0.42 -5.76 -0.3 1.91e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2742417 0.565 rs2673031 chr3:45756986 A/G cg04837898 chr3:45731254 SACM1L -0.53 -8.87 -0.43 4.05e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg13409248 chr3:40428643 ENTPD3 0.5 8.31 0.41 2.27e-15 Renal cell carcinoma; LIHC cis rs1371867 0.817 rs1660314 chr8:101332953 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -9.03 -0.44 1.27e-17 Atrioventricular conduction; LIHC cis rs10751667 0.621 rs7396107 chr11:970029 C/T cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC trans rs11039798 1.000 rs7928243 chr11:48589192 A/T cg15704280 chr7:45808275 SEPT13 0.62 6.44 0.33 4.13e-10 Axial length; LIHC cis rs9303401 0.625 rs34963822 chr17:56988424 C/A cg25039879 chr17:56429692 SUPT4H1 0.78 8.84 0.43 5.22e-17 Cognitive test performance; LIHC cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.883 rs472465 chr11:111468962 C/T cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs2153535 0.601 rs9505472 chr6:8538765 T/C cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.58e-15 Motion sickness; LIHC cis rs5758659 0.653 rs133383 chr22:42473603 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.41 -7.81 -0.39 7.23e-14 Cognitive function; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg24613906 chr8:27452753 NA -0.28 -6.08 -0.31 3.22e-9 Monocyte count; LIHC cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.83e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10193935 0.892 rs12622152 chr2:42482929 C/A cg27598129 chr2:42591480 NA -0.7 -10.37 -0.49 4.24e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs7089973 0.584 rs4752322 chr10:116613258 A/C cg03647239 chr10:116582469 FAM160B1 0.47 6.79 0.34 4.83e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7116495 0.609 rs73543640 chr11:71834374 G/T cg26138937 chr11:71823887 C11orf51 1.32 10.9 0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg20607798 chr8:58055168 NA -0.57 -6.98 -0.35 1.5e-11 Developmental language disorder (linguistic errors); LIHC cis rs9911578 1.000 rs8079774 chr17:56908188 A/G cg12560992 chr17:57184187 TRIM37 0.96 17.4 0.69 5.04e-49 Intelligence (multi-trait analysis); LIHC trans rs78049276 0.512 rs6855875 chr4:148402737 C/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.66 -10.04 -0.48 6.03e-21 Pulse pressure; LIHC cis rs10857712 0.754 rs2297033 chr10:135234848 C/T cg01444801 chr10:135216882 MTG1 -0.63 -9.35 -0.45 1.2e-18 Systemic lupus erythematosus; LIHC cis rs1555322 0.530 rs7004 chr20:33866753 G/C cg17927777 chr20:33865990 NA 0.55 6.39 0.33 5.5e-10 Attention deficit hyperactivity disorder; LIHC cis rs7312933 0.670 rs2406568 chr12:42552297 G/C cg01256987 chr12:42539512 GXYLT1 -0.43 -7.12 -0.36 6.2e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs3617 0.625 rs56019197 chr3:52874753 T/C cg11645453 chr3:52864694 ITIH4 -0.23 -6.2 -0.32 1.62e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04925841 chr12:24715491 SOX5 0.44 6.07 0.31 3.48e-9 Lung function (FEV1/FVC); LIHC cis rs11190604 0.767 rs10883481 chr10:102165021 G/A cg07080220 chr10:102295463 HIF1AN 0.45 6.31 0.32 8.45e-10 Palmitoleic acid (16:1n-7) levels; LIHC cis rs12893668 0.703 rs12894729 chr14:104035292 G/A cg19000871 chr14:103996768 TRMT61A -0.43 -7.01 -0.35 1.28e-11 Reticulocyte count; LIHC cis rs6748734 1.000 rs11893118 chr2:241828308 C/G cg20140201 chr2:241835670 C2orf54 -0.54 -8.37 -0.41 1.49e-15 Urinary metabolites; LIHC cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg03806693 chr22:41940476 POLR3H -1.08 -12.71 -0.57 1.37e-30 Vitiligo; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg11645453 chr3:52864694 ITIH4 0.21 5.72 0.3 2.33e-8 Electroencephalogram traits; LIHC trans rs7618501 0.699 rs2777888 chr3:49898000 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.6 9.42 0.45 6.81e-19 Intelligence (multi-trait analysis); LIHC trans rs9641123 0.578 rs2528540 chr7:93252839 C/G cg09745688 chr16:2908918 PRSS22 -0.37 -6.45 -0.33 3.79e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs1707322 1.000 rs946527 chr1:46485970 C/T cg03146154 chr1:46216737 IPP 0.49 8.02 0.4 1.7e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2204008 0.806 rs35534445 chr12:38279093 C/T cg26384229 chr12:38710491 ALG10B 0.84 10.49 0.49 1.67e-22 Bladder cancer; LIHC cis rs1008375 1.000 rs7694020 chr4:17682597 C/T cg16339924 chr4:17578868 LAP3 0.41 6.0 0.31 4.92e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9303280 0.806 rs12232498 chr17:38040363 T/C cg11212589 chr17:38028394 ZPBP2 0.35 7.1 0.36 7.36e-12 Self-reported allergy; LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg22907277 chr7:1156413 C7orf50 0.56 8.65 0.42 2.11e-16 Longevity;Endometriosis; LIHC cis rs17253792 0.822 rs9972178 chr14:56073480 A/G cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs875971 0.825 rs1000464 chr7:65777909 G/C cg11764359 chr7:65958608 NA -0.84 -14.68 -0.62 3.45e-38 Aortic root size; LIHC cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.52 8.07 0.4 1.19e-14 Schizophrenia; LIHC cis rs17102884 0.506 rs4899541 chr14:75403437 T/G cg08847533 chr14:75593920 NEK9 -0.62 -10.86 -0.51 8.51e-24 Neuroticism; LIHC cis rs1577917 0.655 rs9450311 chr6:86376586 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.41 0.33 4.7e-10 Response to antipsychotic treatment; LIHC cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg22105103 chr4:187893119 NA 0.29 7.18 0.36 4.26e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs9948 0.881 rs7580942 chr2:97468276 C/G cg01990225 chr2:97406019 LMAN2L -0.57 -5.83 -0.3 1.31e-8 Erectile dysfunction and prostate cancer treatment; LIHC cis rs765787 0.530 rs4775835 chr15:45537553 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.76 -0.3 1.84e-8 Total body bone mineral density; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01328164 chr9:35814704 HINT2 -0.41 -6.18 -0.32 1.87e-9 Calcium levels; LIHC cis rs17854409 0.803 rs1063247 chr20:61472118 C/G cg07645718 chr20:61493192 TCFL5 0.79 6.45 0.33 3.85e-10 Obesity-related traits; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg03395511 chr6:291903 DUSP22 -0.48 -6.54 -0.33 2.27e-10 Menopause (age at onset); LIHC cis rs7903847 0.596 rs7922512 chr10:99155685 C/A cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs11098499 0.954 rs6848389 chr4:120402622 A/G cg25214090 chr10:38739885 LOC399744 0.56 9.23 0.45 2.95e-18 Corneal astigmatism; LIHC cis rs10876993 0.789 rs1689600 chr12:58049645 A/T cg15848620 chr12:58087721 OS9 -0.55 -7.43 -0.37 8.96e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs10463316 0.894 rs6891272 chr5:150762842 G/T cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.02e-10 Metabolite levels (Pyroglutamine); LIHC cis rs6840360 0.593 rs4696286 chr4:152606547 G/A cg22705602 chr4:152727874 NA -0.34 -6.95 -0.35 1.83e-11 Intelligence (multi-trait analysis); LIHC cis rs9640161 0.742 rs2108854 chr7:150017408 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 0.46 8.06 0.4 1.31e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7927771 0.832 rs56030824 chr11:47397353 G/A cg20135002 chr11:47629003 NA -0.54 -9.11 -0.44 6.97e-18 Subjective well-being; LIHC cis rs6723226 0.881 rs10181198 chr2:32686582 A/G cg02381751 chr2:32503542 YIPF4 0.77 11.6 0.53 1.8e-26 Intelligence (multi-trait analysis); LIHC trans rs11098499 0.863 rs28718422 chr4:120466304 C/A cg25214090 chr10:38739885 LOC399744 0.59 9.52 0.46 3.25e-19 Corneal astigmatism; LIHC cis rs5758511 0.689 rs5758691 chr22:42668504 G/C cg20195005 chr22:42527684 CYP2D6 0.3 5.74 0.3 2.04e-8 Birth weight; LIHC cis rs1559088 0.600 rs7259117 chr19:33550113 G/T cg27124370 chr19:33622961 WDR88 0.56 8.05 0.4 1.43e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1401999 0.966 rs1533682 chr3:183634879 A/G cg01324343 chr3:183735012 ABCC5 0.73 11.89 0.54 1.58e-27 Anterior chamber depth; LIHC cis rs35306767 0.903 rs11812523 chr10:915638 C/T cg26597838 chr10:835615 NA 1.18 14.34 0.61 7.88e-37 Eosinophil percentage of granulocytes; LIHC cis rs2204008 0.715 rs12368462 chr12:38336116 C/G cg26384229 chr12:38710491 ALG10B 0.61 8.21 0.41 4.59e-15 Bladder cancer; LIHC cis rs3770081 1.000 rs12622009 chr2:86248325 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -9.1 -0.44 7.41e-18 Facial emotion recognition (sad faces); LIHC cis rs12586317 0.513 rs74564132 chr14:35472882 C/T cg05294307 chr14:35346193 BAZ1A -0.5 -7.42 -0.37 9.26e-13 Psoriasis; LIHC trans rs1499614 1.000 rs2659911 chr7:66158420 G/A cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg18252515 chr7:66147081 NA -1.23 -15.51 -0.64 1.89e-41 Diabetic kidney disease; LIHC cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.81 0.3 1.42e-8 Menopause (age at onset); LIHC cis rs2933343 0.649 rs789214 chr3:128594995 A/G cg25356066 chr3:128598488 ACAD9 0.55 7.66 0.38 1.9e-13 IgG glycosylation; LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.69 9.97 0.47 9.89e-21 Lymphocyte counts; LIHC cis rs4713118 0.586 rs9468290 chr6:28087674 C/T cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Parkinson's disease; LIHC cis rs10751667 1.000 rs6597972 chr11:928402 C/T ch.11.42038R chr11:967971 AP2A2 0.59 10.8 0.5 1.32e-23 Alzheimer's disease (late onset); LIHC cis rs7810240 1.000 rs1010614 chr7:150083805 T/C cg10018233 chr7:150070692 REPIN1 -0.41 -6.47 -0.33 3.43e-10 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; LIHC cis rs5769765 0.817 rs11912619 chr22:50317401 G/A cg02269571 chr22:50332266 NA -0.66 -8.9 -0.43 3.32e-17 Schizophrenia; LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg00280220 chr17:61926910 NA 0.42 6.77 0.34 5.73e-11 Prudent dietary pattern; LIHC cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg08280861 chr8:58055591 NA 0.51 6.04 0.31 4.06e-9 Developmental language disorder (linguistic errors); LIHC cis rs2180341 0.782 rs4897214 chr6:127723625 G/T cg24812749 chr6:127587940 RNF146 0.79 12.47 0.56 1.1e-29 Breast cancer; LIHC cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.73 -10.87 -0.51 7.6e-24 Alzheimer's disease; LIHC cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.59 0.46 1.94e-19 Bipolar disorder; LIHC cis rs950776 0.518 rs1504545 chr15:78818471 C/G cg06917634 chr15:78832804 PSMA4 -0.94 -14.19 -0.61 3.02e-36 Sudden cardiac arrest; LIHC cis rs735860 0.726 rs209500 chr6:53188137 A/C cg10236188 chr6:53219634 NA -0.4 -7.41 -0.37 1e-12 Glaucoma; LIHC cis rs10876993 0.928 rs1689596 chr12:58053029 T/C cg15848620 chr12:58087721 OS9 -0.56 -7.6 -0.38 2.84e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs7904368 0.806 rs12242261 chr10:16872929 T/C cg14835575 chr10:16859367 RSU1 0.5 7.65 0.38 2.11e-13 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs7937682 0.602 rs503905 chr11:111390762 G/C cg09085632 chr11:111637200 PPP2R1B -0.46 -6.42 -0.33 4.45e-10 Primary sclerosing cholangitis; LIHC cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg11644478 chr21:40555479 PSMG1 -0.38 -5.81 -0.3 1.46e-8 Cognitive function; LIHC cis rs17102423 0.755 rs11158572 chr14:65577411 C/T cg11161011 chr14:65562177 MAX -0.59 -8.22 -0.41 4.37e-15 Obesity-related traits; LIHC cis rs1018836 0.786 rs10956736 chr8:91602067 C/T cg16814680 chr8:91681699 NA -0.56 -8.91 -0.43 3.11e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs11864453 0.713 rs3764312 chr16:72125733 A/C cg01557791 chr16:72042693 DHODH -0.47 -7.61 -0.38 2.7e-13 Fibrinogen levels; LIHC cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg13395646 chr4:1353034 KIAA1530 0.41 6.4 0.33 5.23e-10 Obesity-related traits; LIHC cis rs7923452 0.507 rs215494 chr10:30776589 T/G cg25182066 chr10:30743637 MAP3K8 -0.68 -10.88 -0.51 7.11e-24 Itch intensity from mosquito bite; LIHC cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg10896456 chr17:42255109 ASB16;C17orf65 0.53 9.78 0.47 4.55e-20 Total body bone mineral density; LIHC cis rs7959452 0.868 rs12812860 chr12:69746671 T/C cg14784868 chr12:69753453 YEATS4 0.74 12.52 0.56 7.42e-30 Blood protein levels; LIHC cis rs6952808 0.771 rs10265944 chr7:1918337 C/T cg20295408 chr7:1910781 MAD1L1 -0.52 -7.5 -0.38 5.49e-13 Bipolar disorder and schizophrenia; LIHC cis rs11690935 0.531 rs62183800 chr2:172867273 C/T cg13550731 chr2:172543902 DYNC1I2 0.44 6.83 0.35 4.01e-11 Schizophrenia; LIHC cis rs6519955 0.866 rs9626920 chr22:46428993 A/G cg05468064 chr22:46423449 NA -0.37 -5.89 -0.3 9.1e-9 Dupuytren's disease; LIHC cis rs9768139 0.708 rs896780 chr7:158113972 C/T cg25566285 chr7:158114605 PTPRN2 0.22 5.96 0.31 6.38e-9 Calcium levels; LIHC cis rs10504229 0.610 rs6987118 chr8:58147851 G/T cg11062466 chr8:58055876 NA 0.42 6.29 0.32 9.84e-10 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg00280220 chr17:61926910 NA 0.4 6.58 0.34 1.81e-10 Prudent dietary pattern; LIHC cis rs7772486 0.806 rs4243478 chr6:146284560 A/G cg23711669 chr6:146136114 FBXO30 -0.58 -10.13 -0.48 3.01e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs933688 1.000 rs12651840 chr5:90729592 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 20.88 0.75 5.2e-63 Smoking behavior; LIHC cis rs17685 0.712 rs7785025 chr7:75628101 C/T cg01364799 chr7:75623366 TMEM120A 0.54 8.4 0.41 1.2e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs829661 0.947 rs829665 chr2:30724701 T/A cg07150166 chr2:30669952 LCLAT1 0.78 6.96 0.35 1.72e-11 Midgestational circulating levels of PBDEs (fetal genetic effect); LIHC cis rs2273156 1.000 rs7141293 chr14:35462910 T/A cg16230307 chr14:35515116 FAM177A1 -0.41 -6.07 -0.31 3.45e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs2404602 0.692 rs55864032 chr15:77122548 A/G cg23625390 chr15:77176239 SCAPER 0.36 5.87 0.3 1.04e-8 Blood metabolite levels; LIHC cis rs77669868 0.568 rs3825045 chr11:114073200 C/T cg01914181 chr11:114070210 ZBTB16 0.49 5.78 0.3 1.65e-8 Monocyte percentage of white cells; LIHC cis rs11122272 0.766 rs2790872 chr1:231540543 A/T cg06096015 chr1:231504339 EGLN1 0.48 9.12 0.44 6.77e-18 Hemoglobin concentration; LIHC cis rs9914988 0.832 rs4795462 chr17:27130991 C/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.86 -0.35 3.23e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6582630 0.519 rs8189609 chr12:38281408 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.71 0.5 2.77e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs2991971 1.000 rs2993262 chr1:46013733 G/C cg03146154 chr1:46216737 IPP -0.38 -5.84 -0.3 1.23e-8 High light scatter reticulocyte count; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg01238044 chr22:24384105 GSTT1 0.49 6.27 0.32 1.06e-9 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs2380220 0.872 rs66723559 chr6:95956338 T/C cg04719120 chr6:96025338 MANEA -0.59 -6.21 -0.32 1.52e-9 Behavioural disinhibition (generation interaction); LIHC cis rs8180040 1.000 rs11714294 chr3:47339723 G/A cg16586182 chr3:47516702 SCAP 0.58 10.56 0.5 9.27e-23 Colorectal cancer; LIHC cis rs743757 1.000 rs2236979 chr3:50486895 T/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.16 0.32 2.04e-9 Diastolic blood pressure; LIHC cis rs9814567 1.000 rs9990351 chr3:134239191 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.66 12.24 0.55 8.34e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs727505 0.954 rs59379598 chr7:124596903 C/G cg23710748 chr7:124431027 NA -0.34 -6.04 -0.31 4.07e-9 Lewy body disease; LIHC cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg16145915 chr7:1198662 ZFAND2A -0.34 -8.22 -0.41 4.23e-15 Longevity;Endometriosis; LIHC cis rs12478296 0.786 rs55876934 chr2:243033816 C/T cg18898632 chr2:242989856 NA -0.56 -7.56 -0.38 3.7e-13 Obesity-related traits; LIHC trans rs61931739 0.534 rs814669 chr12:34102459 C/T cg26384229 chr12:38710491 ALG10B 0.49 6.9 0.35 2.55e-11 Morning vs. evening chronotype; LIHC trans rs2727020 0.729 rs1164666 chr11:49295867 C/T cg15704280 chr7:45808275 SEPT13 -0.89 -16.21 -0.66 3.15e-44 Coronary artery disease; LIHC cis rs12594515 1.000 rs8026221 chr15:45987910 G/T cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.71e-10 Waist circumference;Weight; LIHC cis rs7149337 1.000 rs7149337 chr14:51709017 G/T cg23942311 chr14:51606299 NA 0.35 6.71 0.34 7.97e-11 Cancer; LIHC cis rs11098499 0.562 rs13101722 chr4:120555975 C/A cg09307838 chr4:120376055 NA -0.57 -8.75 -0.43 1e-16 Corneal astigmatism; LIHC cis rs12477438 0.520 rs6542865 chr2:99764521 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.8 0.65 1.35e-42 Chronic sinus infection; LIHC trans rs7120489 0.643 rs12276659 chr11:12447289 T/C cg08537300 chr5:179058959 NA 0.57 6.18 0.32 1.84e-9 Mortality in heart failure; LIHC cis rs3762637 1.000 rs12633461 chr3:122135897 C/G cg24169773 chr3:122142474 KPNA1 -0.5 -9.66 -0.46 1.11e-19 LDL cholesterol levels; LIHC cis rs780096 0.526 rs7602534 chr2:27592423 C/T cg21248554 chr2:27665150 KRTCAP3 -0.43 -5.81 -0.3 1.4e-8 Total body bone mineral density; LIHC cis rs6754311 0.773 rs632632 chr2:136638216 A/G cg17750252 chr2:136567154 LCT -0.36 -6.48 -0.33 3.16e-10 Mosquito bite size; LIHC cis rs7772486 0.875 rs1331637 chr6:146337087 T/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.1 -0.31 2.9e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs611744 0.967 rs635624 chr8:109197799 G/C cg21045802 chr8:109455806 TTC35 0.51 8.79 0.43 7.57e-17 Dupuytren's disease; LIHC cis rs9911578 0.835 rs3744093 chr17:56492800 T/C cg12560992 chr17:57184187 TRIM37 -0.89 -14.65 -0.62 4.82e-38 Intelligence (multi-trait analysis); LIHC cis rs4925166 1 rs4925166 chr17:18210810 T/G cg04261877 chr17:18218829 SMCR8;TOP3A 0.42 6.27 0.32 1.12e-9 Multiple sclerosis; LIHC cis rs559928 0.557 rs7122408 chr11:63898826 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.73 6.4 0.33 5.14e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs2274273 0.870 rs6573009 chr14:55682324 A/C cg01864836 chr14:55583639 NA -0.4 -7.61 -0.38 2.61e-13 Protein biomarker; LIHC cis rs34779708 0.966 rs4934732 chr10:35431684 T/C cg03585969 chr10:35415529 CREM 0.85 12.9 0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4423214 0.819 rs7938885 chr11:71170043 T/C cg24826892 chr11:71159390 DHCR7 0.47 6.12 0.31 2.55e-9 Vitamin D levels; LIHC cis rs1003719 0.679 rs2835674 chr21:38581522 T/A cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.21 -0.48 1.54e-21 Eye color traits; LIHC cis rs904251 0.698 rs2646926 chr6:37424988 G/A cg01843034 chr6:37503916 NA -0.39 -6.21 -0.32 1.51e-9 Cognitive performance; LIHC cis rs9783347 1.000 rs4150612 chr11:18364358 G/T cg15585147 chr11:18324498 HPS5 0.38 6.15 0.32 2.17e-9 Pancreatic cancer; LIHC cis rs919433 0.680 rs699319 chr2:198281776 C/A cg10820045 chr2:198174542 NA 0.55 8.95 0.44 2.22e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs3780486 0.846 rs3824458 chr9:33144809 C/T cg20290983 chr6:43655470 MRPS18A 1.17 29.81 0.85 4.05e-97 IgG glycosylation; LIHC cis rs6750047 0.609 rs2121259 chr2:38269475 T/C cg07380506 chr2:38303506 CYP1B1 0.58 7.32 0.37 1.79e-12 Cutaneous malignant melanoma;Melanoma; LIHC cis rs362296 0.698 rs3095072 chr4:3263325 G/A cg06533319 chr4:3265114 C4orf44 0.35 6.44 0.33 4.11e-10 Parental longevity (mother's age at death); LIHC cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg13607699 chr17:42295918 UBTF 0.45 7.18 0.36 4.51e-12 Total body bone mineral density; LIHC cis rs765787 0.530 rs4442750 chr15:45535328 G/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg11764359 chr7:65958608 NA -0.57 -6.07 -0.31 3.45e-9 Diabetic kidney disease; LIHC cis rs7927771 0.524 rs7943213 chr11:47715524 T/C cg20307385 chr11:47447363 PSMC3 0.77 11.58 0.53 2.15e-26 Subjective well-being; LIHC cis rs11676348 0.846 rs4674260 chr2:219002376 T/C cg00012203 chr2:219082015 ARPC2 -0.55 -7.66 -0.38 1.88e-13 Ulcerative colitis; LIHC cis rs76419734 0.510 rs2553461 chr4:106731410 A/G cg24545054 chr4:106630052 GSTCD;INTS12 -0.67 -6.92 -0.35 2.18e-11 Post bronchodilator FEV1; LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs636291 0.500 rs655271 chr1:10536635 G/A cg07384165 chr1:10488281 NA -0.32 -5.76 -0.3 1.85e-8 Prostate cancer; LIHC cis rs9486715 0.867 rs926277 chr6:96868837 T/A cg06623918 chr6:96969491 KIAA0776 0.86 14.87 0.63 6.41e-39 Headache; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17482927 chr17:63133259 RGS9 0.49 6.98 0.35 1.57e-11 Pancreatic cancer; LIHC cis rs2295359 0.892 rs11209004 chr1:67613932 G/A cg08029281 chr1:67600428 NA 0.37 6.21 0.32 1.54e-9 Psoriasis; LIHC cis rs6754311 0.552 rs1030765 chr2:136553188 A/T cg15123519 chr2:136567270 LCT 0.44 8.45 0.42 8.73e-16 Mosquito bite size; LIHC cis rs7618501 0.633 rs12485600 chr3:50025530 A/G cg24110177 chr3:50126178 RBM5 -0.48 -7.73 -0.39 1.21e-13 Intelligence (multi-trait analysis); LIHC cis rs4423214 1.000 rs12791871 chr11:71164544 A/C cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs8044995 0.563 rs57434514 chr16:68402649 G/A cg09835421 chr16:68378352 PRMT7 -0.8 -8.97 -0.44 2.05e-17 Schizophrenia; LIHC trans rs9914544 0.505 rs4924774 chr17:18794920 A/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.46 -0.33 3.65e-10 Educational attainment (years of education); LIHC cis rs9905704 0.647 rs2036730 chr17:57038282 A/G cg12560992 chr17:57184187 TRIM37 0.68 9.93 0.47 1.38e-20 Testicular germ cell tumor; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg07677032 chr17:61819896 STRADA 0.43 6.14 0.32 2.23e-9 Prudent dietary pattern; LIHC cis rs922107 0.738 rs4658280 chr1:90022971 G/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.83 -0.39 6.2e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7617773 0.694 rs13099560 chr3:48204768 C/T cg11946769 chr3:48343235 NME6 -0.63 -8.58 -0.42 3.28e-16 Coronary artery disease; LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg10150615 chr22:24372951 LOC391322 -0.58 -8.31 -0.41 2.23e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4819052 0.788 rs35323494 chr21:46703739 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.68 9.64 0.46 1.3e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1904096 0.506 rs4693381 chr4:95206855 A/T cg11021082 chr4:95130006 SMARCAD1 0.5 9.39 0.45 9e-19 Type 2 diabetes; LIHC cis rs1008375 1.000 rs4698641 chr4:17642630 C/T cg02297831 chr4:17616191 MED28 0.5 7.71 0.38 1.36e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg00800038 chr16:89945340 TCF25 -0.68 -10.66 -0.5 4.19e-23 Skin colour saturation; LIHC cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg23205692 chr1:25664452 TMEM50A -0.39 -6.34 -0.32 7.28e-10 Erythrocyte sedimentation rate; LIHC cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg12292205 chr6:26970375 C6orf41 0.45 7.64 0.38 2.16e-13 Schizophrenia; LIHC trans rs2243480 1.000 rs35542501 chr7:65431215 T/C cg10756647 chr7:56101905 PSPH 1.1 13.62 0.59 4.65e-34 Diabetic kidney disease; LIHC cis rs8180040 0.967 rs807935 chr3:47321669 A/G cg27129171 chr3:47204927 SETD2 0.64 11.01 0.51 2.46e-24 Colorectal cancer; LIHC cis rs6933660 0.800 rs3800273 chr6:151759035 G/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.55 -8.29 -0.41 2.71e-15 Menarche (age at onset); LIHC cis rs7208859 0.673 rs999797 chr17:29159329 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.85 0.35 3.45e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs798766 1.000 rs1665362 chr4:1726367 T/A cg21231739 chr4:1642635 FAM53A -0.37 -5.89 -0.3 9.23e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs539514 0.612 rs1830760 chr13:76296625 G/A cg04757411 chr13:76259545 LMO7 -0.46 -7.76 -0.39 9.65e-14 Type 1 diabetes; LIHC cis rs1712517 0.873 rs1712510 chr10:105009086 A/G cg05636881 chr10:105038444 INA -0.43 -6.98 -0.35 1.53e-11 Migraine; LIHC cis rs7089973 0.584 rs6585300 chr10:116639889 A/C cg03647239 chr10:116582469 FAM160B1 0.47 6.88 0.35 2.95e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs6717918 0.517 rs2633262 chr2:233130584 T/C cg19760917 chr1:2411643 PLCH2 -0.4 -6.24 -0.32 1.29e-9 Height; LIHC cis rs7534824 0.507 rs61780294 chr1:101398011 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.57 0.38 3.53e-13 Refractive astigmatism; LIHC cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg20295408 chr7:1910781 MAD1L1 -0.44 -6.37 -0.33 6.01e-10 Bipolar disorder and schizophrenia; LIHC cis rs16828019 0.704 rs12031277 chr1:41491801 A/G cg03962019 chr1:41807865 NA 0.5 7.0 0.35 1.38e-11 Intelligence (multi-trait analysis); LIHC cis rs11871801 0.517 rs646123 chr17:40720632 G/A cg14558262 chr17:40713999 COASY 0.63 9.76 0.47 5.2e-20 Crohn's disease; LIHC cis rs3770081 1.000 rs74733602 chr2:86303442 T/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.88 -8.69 -0.43 1.49e-16 Facial emotion recognition (sad faces); LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg15586393 chr4:1244086 CTBP1;C4orf42 -0.43 -6.1 -0.31 2.86e-9 Longevity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03558299 chr20:47662597 CSE1L 0.49 6.95 0.35 1.84e-11 Pancreatic cancer; LIHC cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg20607798 chr8:58055168 NA 0.69 7.73 0.39 1.25e-13 Developmental language disorder (linguistic errors); LIHC trans rs1075232 0.677 rs72714666 chr15:31492226 T/C cg04373760 chr16:53404718 NA 0.55 6.4 0.33 5.11e-10 Survival in colorectal cancer (non-distant metastatic); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12173535 chr19:54694174 MBOAT7;TSEN34 0.39 6.2 0.32 1.61e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11711311 1.000 rs9848993 chr3:113497914 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.84 -0.35 3.69e-11 IgG glycosylation; LIHC cis rs4819052 1.000 rs2838830 chr21:46664227 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.71 9.46 0.46 4.99e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.0 -0.31 5.01e-9 Diastolic blood pressure; LIHC cis rs6952808 0.929 rs2280550 chr7:1976556 G/A cg04267008 chr7:1944627 MAD1L1 -0.65 -10.38 -0.49 4e-22 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg20302342 chr1:156215951 PAQR6 0.32 6.03 0.31 4.32e-9 Tonsillectomy; LIHC cis rs12249377 0.519 rs7906960 chr10:92586205 A/G cg14313238 chr10:92632228 RPP30 0.38 6.37 0.33 5.94e-10 White matter microstructure (global fractional anisotropy); LIHC cis rs8060686 0.565 rs8044328 chr16:68146859 G/C cg05110241 chr16:68378359 PRMT7 -0.57 -6.61 -0.34 1.48e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs6690583 0.623 rs2028304 chr1:85488030 G/A cg22153463 chr1:85462885 MCOLN2 -0.48 -5.92 -0.3 7.98e-9 Serum sulfate level; LIHC cis rs2820292 1.000 rs1032524 chr1:201790826 C/T cg11586189 chr1:201857591 SHISA4 -0.41 -6.18 -0.32 1.81e-9 Waist circumference;Body mass index (joint analysis main effects and smoking interaction);Body mass index;BMI in non-smokers;BMI (adjusted for smoking behaviour); LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs3008870 0.755 rs2815364 chr1:67498384 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.66 11.22 0.52 4.19e-25 Lymphocyte percentage of white cells; LIHC cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.779 rs28495013 chr4:120375831 A/C cg25214090 chr10:38739885 LOC399744 0.61 9.85 0.47 2.57e-20 Corneal astigmatism; LIHC trans rs1728785 1.000 rs1099296 chr16:68588653 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.39 0.33 5.55e-10 Ulcerative colitis; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg02993280 chr1:107599747 PRMT6 -0.7 -11.34 -0.52 1.56e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2274273 0.840 rs7153110 chr14:55820628 A/G cg04306507 chr14:55594613 LGALS3 0.32 6.08 0.31 3.25e-9 Protein biomarker; LIHC cis rs1707322 0.721 rs11211151 chr1:46112752 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1997103 1.000 rs6966183 chr7:55407546 A/C cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1200821 0.535 rs1208784 chr10:37768433 A/G cg00409905 chr10:38381863 ZNF37A -0.37 -5.85 -0.3 1.15e-8 Hemostatic factors and hematological phenotypes; LIHC cis rs910316 0.967 rs175432 chr14:75615246 C/G cg11812906 chr14:75593930 NEK9 -0.74 -14.52 -0.62 1.53e-37 Height; LIHC cis rs2386661 0.712 rs11259544 chr10:5646708 T/C cg17085576 chr10:5658249 NA -0.33 -6.25 -0.32 1.22e-9 Breast cancer; LIHC cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg27170947 chr2:26402098 FAM59B 0.65 8.36 0.41 1.64e-15 Gut microbiome composition (summer); LIHC cis rs9549367 0.577 rs3024711 chr13:113813268 A/G cg18105134 chr13:113819100 PROZ -0.76 -11.79 -0.54 3.72e-27 Platelet distribution width; LIHC trans rs11148252 0.875 rs9596651 chr13:52938582 A/G cg18335740 chr13:41363409 SLC25A15 -0.38 -6.61 -0.34 1.49e-10 Lewy body disease; LIHC cis rs8067545 0.750 rs9915758 chr17:19964775 A/G cg13482628 chr17:19912719 NA 0.5 8.4 0.41 1.17e-15 Schizophrenia; LIHC cis rs6867032 0.527 rs13162781 chr5:2012235 C/T cg26168224 chr5:2018326 NA 0.28 6.67 0.34 1.02e-10 Gut microbiome composition (winter); LIHC cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 12.63 0.56 2.73e-30 Alzheimer's disease; LIHC cis rs858239 0.698 rs858295 chr7:23245569 A/G cg18081818 chr7:23246105 NA -0.46 -7.06 -0.36 9.47e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg09455208 chr3:40491958 NA -0.4 -8.03 -0.4 1.54e-14 Renal cell carcinoma; LIHC cis rs546131 0.820 rs744841 chr11:34857667 G/A cg11058730 chr11:34937778 PDHX;APIP 0.63 9.34 0.45 1.3e-18 Lung disease severity in cystic fibrosis; LIHC cis rs8114671 0.836 rs2038504 chr20:33648187 T/C cg07148914 chr20:33460835 GGT7 -0.56 -8.45 -0.42 8.7e-16 Height; LIHC cis rs7633770 0.735 rs12491294 chr3:46688498 G/T cg11219411 chr3:46661640 NA -0.43 -7.49 -0.38 6.02e-13 Coronary artery disease; LIHC cis rs4843747 0.671 rs28679286 chr16:88106307 C/T cg00677901 chr16:88017247 BANP 0.51 7.85 0.39 5.52e-14 Menopause (age at onset); LIHC cis rs6456156 0.586 rs720325 chr6:167467349 G/T cg12798992 chr6:167411361 FGFR1OP 0.43 6.6 0.34 1.53e-10 Primary biliary cholangitis; LIHC cis rs12220238 1.000 rs7073432 chr10:75953350 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.38 0.33 5.76e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs6942756 0.513 rs10954224 chr7:128893513 T/A cg02491457 chr7:128862824 NA 0.59 9.79 0.47 4.21e-20 White matter hyperintensity burden; LIHC cis rs769267 0.930 rs4808967 chr19:19640524 A/G cg03709012 chr19:19516395 GATAD2A 0.96 15.6 0.64 8.17e-42 Tonsillectomy; LIHC cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.68 0.34 9.67e-11 Bipolar disorder; LIHC cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg11764359 chr7:65958608 NA 0.57 5.82 0.3 1.39e-8 Diabetic kidney disease; LIHC cis rs3749237 0.576 rs62259939 chr3:49386047 G/A cg06212747 chr3:49208901 KLHDC8B 0.45 5.79 0.3 1.6e-8 Resting heart rate; LIHC cis rs8067354 0.574 rs2526354 chr17:57976658 A/G cg02344993 chr17:57696989 CLTC 0.66 10.37 0.49 4.25e-22 Hemoglobin concentration; LIHC cis rs11792861 0.816 rs7021366 chr9:111727670 C/G cg05043794 chr9:111880884 C9orf5 -0.28 -6.7 -0.34 8.43e-11 Menarche (age at onset); LIHC cis rs7674212 0.541 rs2251322 chr4:104079424 C/T cg16532752 chr4:104119610 CENPE -0.46 -7.39 -0.37 1.11e-12 Type 2 diabetes; LIHC cis rs9916302 0.904 rs13341996 chr17:37536862 C/T cg00129232 chr17:37814104 STARD3 0.4 6.34 0.32 7.42e-10 Glomerular filtration rate (creatinine); LIHC cis rs10779751 0.734 rs1194820 chr1:11129259 A/C cg08854313 chr1:11322531 MTOR 0.77 13.14 0.58 3.37e-32 Body mass index; LIHC cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC cis rs7903847 0.612 rs9887994 chr10:99159815 T/G cg08345082 chr10:99160200 RRP12 -0.38 -6.09 -0.31 3.1e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg15290081 chr7:76254647 POMZP3;LOC100133091 0.46 7.06 0.36 9.06e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1577917 0.958 rs12207374 chr6:86656645 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.29 -0.49 8.14e-22 Response to antipsychotic treatment; LIHC cis rs6445975 0.688 rs2271633 chr3:58260073 A/G cg23715586 chr3:58305044 RPP14 -0.34 -5.87 -0.3 1.03e-8 Systemic lupus erythematosus; LIHC cis rs7635838 0.892 rs7644968 chr3:11489493 C/T cg00170343 chr3:11313890 ATG7 0.43 6.7 0.34 8.7e-11 HDL cholesterol; LIHC cis rs12220238 0.841 rs11000993 chr10:76084111 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.27 0.32 1.07e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2742417 0.603 rs2673032 chr3:45756927 C/T cg04837898 chr3:45731254 SACM1L -0.53 -8.87 -0.43 4.05e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs17152411 0.895 rs61872121 chr10:126586795 T/C cg07906193 chr10:126599966 NA 0.44 6.89 0.35 2.74e-11 Height; LIHC cis rs7618501 0.602 rs6780731 chr3:50017478 A/G cg24110177 chr3:50126178 RBM5 -0.48 -7.73 -0.39 1.22e-13 Intelligence (multi-trait analysis); LIHC cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg11987759 chr7:65425863 GUSB -0.39 -6.16 -0.32 1.99e-9 Aortic root size; LIHC cis rs8044995 0.563 rs56899435 chr16:68395675 G/A cg05110241 chr16:68378359 PRMT7 -0.85 -9.52 -0.46 3.26e-19 Schizophrenia; LIHC cis rs1878931 0.507 rs1218762 chr16:3405986 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -8.7 -0.43 1.4e-16 Body mass index (adult); LIHC cis rs4803468 0.904 rs60781668 chr19:41944842 A/T cg14132834 chr19:41945861 ATP5SL 0.43 6.24 0.32 1.32e-9 Height; LIHC cis rs8064299 0.597 rs4789097 chr17:72781208 C/T cg25054828 chr17:72772726 NAT9;TMEM104 -0.83 -15.4 -0.64 5.18e-41 Monocyte count; LIHC cis rs7098414 0.511 rs7899513 chr10:82150559 G/A cg00277334 chr10:82204260 NA -0.6 -9.8 -0.47 3.84e-20 Post bronchodilator FEV1; LIHC cis rs2153535 0.580 rs2184584 chr6:8468407 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs17270561 0.887 rs717551 chr6:25855624 T/C cg17691542 chr6:26056736 HIST1H1C 0.79 8.77 0.43 8.37e-17 Iron status biomarkers; LIHC cis rs34779708 0.931 rs35126129 chr10:35452141 G/A cg04310649 chr10:35416472 CREM -0.43 -5.72 -0.3 2.33e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1127311 1.000 rs10908419 chr1:154567699 G/A cg17218026 chr1:154582156 ADAR 0.35 6.8 0.34 4.8e-11 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs4718428 0.672 rs36038499 chr7:66289615 A/G cg18252515 chr7:66147081 NA -0.69 -9.36 -0.45 1.08e-18 Corneal structure; LIHC trans rs800082 0.934 rs1007566 chr3:144311752 G/A cg24215973 chr2:240111563 HDAC4 -0.42 -6.1 -0.31 2.92e-9 Smoking behavior; LIHC cis rs992157 0.798 rs12053514 chr2:219167965 C/T cg00012203 chr2:219082015 ARPC2 -0.83 -13.26 -0.58 1.16e-32 Colorectal cancer; LIHC cis rs7089973 0.604 rs61596353 chr10:116597763 T/C cg23260525 chr10:116636907 FAM160B1 0.35 7.05 0.36 1.02e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs1814175 0.645 rs11040702 chr11:50024827 C/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg01765077 chr12:122356316 WDR66 -0.53 -8.3 -0.41 2.5e-15 Mean corpuscular volume; LIHC cis rs12142240 0.698 rs72679807 chr1:46846490 G/A cg14993813 chr1:46806288 NSUN4 -0.65 -5.89 -0.3 9.4e-9 Menopause (age at onset); LIHC cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg14829360 chr17:73884958 NA -0.52 -7.46 -0.37 7.14e-13 Psoriasis; LIHC cis rs11971779 0.680 rs17691238 chr7:139052284 A/G cg07862535 chr7:139043722 LUC7L2 -0.57 -9.88 -0.47 2.04e-20 Diisocyanate-induced asthma; LIHC cis rs9372498 0.505 rs1690654 chr6:118654172 A/G cg01339444 chr6:118972232 C6orf204 0.71 6.24 0.32 1.26e-9 Diastolic blood pressure; LIHC cis rs6500602 0.634 rs2270365 chr16:4526758 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.19 0.32 1.76e-9 Schizophrenia; LIHC cis rs7582180 0.585 rs13031711 chr2:100939433 T/C cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.966 rs2337986 chr5:140160622 C/T cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6831256 1.000 rs6831256 chr4:3473139 A/G cg15867164 chr4:3464754 DOK7 -0.42 -7.17 -0.36 4.6e-12 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs7772486 0.875 rs2814875 chr6:146305810 G/A cg23711669 chr6:146136114 FBXO30 0.67 11.44 0.53 6.89e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9733 0.519 rs3768005 chr1:150680988 A/T cg13175981 chr1:150552382 MCL1 -0.42 -5.74 -0.3 2.12e-8 Tonsillectomy; LIHC cis rs765787 0.530 rs4238377 chr15:45541981 A/G cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC cis rs7914558 0.966 rs4917997 chr10:104945213 A/G cg15744005 chr10:104629667 AS3MT -0.38 -8.55 -0.42 4.22e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8062405 0.755 rs7193402 chr16:28586127 A/G cg00204512 chr16:28754710 NA 0.41 7.11 0.36 6.83e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4423214 0.921 rs12807827 chr11:71203790 A/C cg24826892 chr11:71159390 DHCR7 0.45 5.77 0.3 1.8e-8 Vitamin D levels; LIHC cis rs8103278 1.000 rs8109951 chr19:46289503 C/T cg11657440 chr19:46296263 DMWD -0.54 -8.53 -0.42 4.93e-16 Coronary artery disease; LIHC cis rs6952808 0.929 rs2280548 chr7:1976667 G/T cg20295408 chr7:1910781 MAD1L1 -0.45 -6.54 -0.33 2.28e-10 Bipolar disorder and schizophrenia; LIHC cis rs1451375 0.617 rs880029 chr7:50569927 G/C cg14593290 chr7:50529359 DDC -0.61 -9.94 -0.47 1.31e-20 Malaria; LIHC cis rs2153535 0.580 rs4960412 chr6:8438261 G/C cg21535247 chr6:8435926 SLC35B3 0.61 7.88 0.39 4.36e-14 Motion sickness; LIHC cis rs9649213 0.593 rs1076272 chr7:98031005 C/G cg08684580 chr7:98029266 BAIAP2L1 -0.39 -6.08 -0.31 3.18e-9 Prostate cancer (SNP x SNP interaction); LIHC trans rs208515 0.556 rs12214562 chr6:66681011 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.74 0.43 1.06e-16 Exhaled nitric oxide levels; LIHC cis rs2952156 0.684 rs11658786 chr17:37815899 G/A cg00129232 chr17:37814104 STARD3 -0.59 -11.55 -0.53 2.89e-26 Asthma; LIHC cis rs4595586 0.525 rs73096109 chr12:39355720 C/A cg26384229 chr12:38710491 ALG10B 0.53 6.34 0.32 7.3e-10 Morning vs. evening chronotype; LIHC trans rs60843830 0.928 rs55742348 chr2:217563 T/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.6 8.43 0.41 9.6e-16 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs79057730 0.599 rs4333501 chr7:803244 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.78 8.91 0.43 3.18e-17 Initial pursuit acceleration; LIHC cis rs769267 0.930 rs4808967 chr19:19640524 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.55 0.38 3.95e-13 Tonsillectomy; LIHC cis rs7131987 0.903 rs10843373 chr12:29420608 A/T cg16970926 chr12:29381810 FAR2 0.31 6.6 0.34 1.61e-10 QT interval; LIHC cis rs9649213 0.614 rs1006169 chr7:97938443 A/G cg09267113 chr7:98030324 BAIAP2L1 0.56 9.78 0.47 4.52e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs10504229 0.593 rs11781042 chr8:57993056 A/T cg20607798 chr8:58055168 NA 0.46 6.15 0.32 2.11e-9 Developmental language disorder (linguistic errors); LIHC cis rs77741769 0.534 rs58918988 chr12:121332953 G/A cg02419362 chr12:121203948 SPPL3 0.34 5.92 0.3 8e-9 Mean corpuscular volume; LIHC cis rs288342 0.829 rs288243 chr2:183661310 C/G cg02625481 chr2:183667124 NA -0.28 -5.86 -0.3 1.11e-8 Recurrent major depressive disorder; LIHC cis rs7662987 0.517 rs2851286 chr4:100014976 A/G cg12011299 chr4:100065546 ADH4 -0.61 -10.08 -0.48 4.31e-21 Smoking initiation; LIHC cis rs7666738 0.830 rs13110410 chr4:98920018 T/C cg05340658 chr4:99064831 C4orf37 0.65 12.1 0.55 2.64e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs730775 0.505 rs325001 chr6:44270936 A/G cg21130236 chr6:44246755 TMEM151B 0.22 6.37 0.33 5.98e-10 Monocyte percentage of white cells;Monocyte count; LIHC cis rs7258465 1.000 rs10427083 chr19:18550276 C/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.38 -0.37 1.2e-12 Breast cancer; LIHC trans rs35110281 0.782 rs6518302 chr21:45018478 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.11 0.31 2.7e-9 Mean corpuscular volume; LIHC cis rs921968 0.591 rs13421421 chr2:219519286 A/G cg18887096 chr2:219472410 PLCD4 0.38 6.72 0.34 7.81e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg12419862 chr22:24373484 LOC391322 0.68 9.94 0.47 1.3e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7208859 0.673 rs9895684 chr17:29242600 G/A cg14067834 chr17:29058358 SUZ12P 0.63 6.04 0.31 4.01e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs908922 0.676 rs12059256 chr1:152515431 G/A cg20991723 chr1:152506922 NA 0.53 9.23 0.45 2.89e-18 Hair morphology; LIHC cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg08219700 chr8:58056026 NA 0.58 7.02 0.35 1.19e-11 Developmental language disorder (linguistic errors); LIHC cis rs2404602 1.000 rs2056544 chr15:76826003 G/A cg03037974 chr15:76606532 NA 0.72 13.82 0.6 8.32e-35 Blood metabolite levels; LIHC trans rs7618501 0.902 rs7645061 chr3:49868842 C/T cg21582582 chr3:182698605 DCUN1D1 0.54 7.13 0.36 6.18e-12 Intelligence (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05794813 chr7:1057827 C7orf50 -0.27 -6.1 -0.31 2.87e-9 Calcium levels; LIHC cis rs7208859 0.524 rs8069400 chr17:29075967 G/T cg13385521 chr17:29058706 SUZ12P 0.81 7.9 0.39 3.84e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg16049864 chr8:95962084 TP53INP1 -0.63 -12.01 -0.54 5.83e-28 Type 2 diabetes; LIHC cis rs17685 0.712 rs2158867 chr7:75815141 C/A cg04592579 chr7:75616294 TMEM120A 0.4 6.89 0.35 2.7e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2228479 0.850 rs11644213 chr16:89837367 C/T cg00800038 chr16:89945340 TCF25 0.6 8.64 0.42 2.14e-16 Skin colour saturation; LIHC cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg09455208 chr3:40491958 NA -0.34 -6.78 -0.34 5.36e-11 Renal cell carcinoma; LIHC cis rs1008375 0.932 rs9291660 chr4:17663414 A/G cg02297831 chr4:17616191 MED28 0.42 5.82 0.3 1.35e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2573652 0.722 rs11636047 chr15:100543341 A/G cg09918751 chr15:100517450 ADAMTS17 -0.69 -11.91 -0.54 1.37e-27 Height; LIHC cis rs9393777 0.623 rs7756567 chr6:26481642 T/G cg12826209 chr6:26865740 GUSBL1 0.66 6.97 0.35 1.65e-11 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.837 rs11612397 chr12:38357455 T/C cg26384229 chr12:38710491 ALG10B 0.6 8.25 0.41 3.42e-15 Bladder cancer; LIHC trans rs4356975 0.522 rs7679184 chr4:69965930 C/G cg18043070 chr17:72199725 RPL38 -0.42 -6.42 -0.33 4.45e-10 Obesity-related traits; LIHC trans rs6934970 1.000 rs6934970 chr6:113124301 A/G cg02462569 chr6:150064036 NUP43 0.44 6.04 0.31 4.09e-9 Bipolar disorder (body mass index interaction); LIHC cis rs507080 0.922 rs546890 chr11:118557198 T/C cg04173919 chr11:118528438 PHLDB1 0.35 6.56 0.33 2.01e-10 Serum metabolite levels; LIHC cis rs807029 0.533 rs735137 chr10:102735835 C/G cg17130504 chr10:102756923 LZTS2 0.56 7.88 0.39 4.34e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4911259 0.552 rs13037833 chr20:31459562 C/T cg13636640 chr20:31349939 DNMT3B -0.61 -10.78 -0.5 1.55e-23 Inflammatory bowel disease; LIHC cis rs9952991 1.000 rs9952991 chr18:12780464 G/A cg23598886 chr18:12777645 NA 0.48 6.48 0.33 3.27e-10 Inflammatory skin disease; LIHC cis rs600806 0.850 rs4970751 chr1:109896600 A/C cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs12791968 0.765 rs12226848 chr11:45009204 C/T cg11846598 chr11:44996168 LOC221122 -0.4 -6.36 -0.33 6.46e-10 Inhibitory control; LIHC cis rs9486719 1.000 rs2472895 chr6:96870387 A/T cg06623918 chr6:96969491 KIAA0776 0.74 7.29 0.37 2.22e-12 Migraine;Coronary artery disease; LIHC cis rs244293 0.965 rs244339 chr17:53200114 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.5 -0.38 5.39e-13 Menarche (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg17417191 chr1:218458683 RRP15 -0.48 -6.23 -0.32 1.35e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg07677032 chr17:61819896 STRADA 0.44 6.44 0.33 4.01e-10 Prudent dietary pattern; LIHC cis rs8180040 0.654 rs6773521 chr3:47234419 A/G cg27129171 chr3:47204927 SETD2 -0.57 -9.45 -0.45 5.69e-19 Colorectal cancer; LIHC cis rs2549003 1.000 rs7734334 chr5:131815004 C/A cg02551604 chr5:131831745 NA -0.43 -6.52 -0.33 2.51e-10 Asthma (sex interaction); LIHC cis rs6500602 0.561 rs62039231 chr16:4519548 A/G cg08645402 chr16:4508243 NA 0.46 8.89 0.43 3.49e-17 Schizophrenia; LIHC cis rs875971 1.000 rs7781698 chr7:65896312 A/T cg11764359 chr7:65958608 NA 0.9 16.44 0.66 3.72e-45 Aortic root size; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg26338869 chr17:61819248 STRADA 0.59 8.68 0.43 1.61e-16 Prudent dietary pattern; LIHC cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg16414030 chr3:133502952 NA -0.42 -6.5 -0.33 2.83e-10 Iron status biomarkers; LIHC cis rs6076065 0.748 rs1016628 chr20:23398738 C/G cg11657817 chr20:23433608 CST11 -0.31 -6.67 -0.34 1.04e-10 Facial morphology (factor 15, philtrum width); LIHC cis rs8062405 0.964 rs7193733 chr16:28875482 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg09222892 chr1:25734099 RHCE -0.44 -7.88 -0.39 4.35e-14 Plateletcrit;Mean corpuscular volume; LIHC cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg10360323 chr17:41437877 NA 0.4 5.97 0.31 5.87e-9 Menopause (age at onset); LIHC cis rs12079745 1.000 rs11810815 chr1:169329790 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.79 -7.06 -0.36 9.27e-12 QT interval; LIHC cis rs4780401 0.609 rs12927966 chr16:11814562 C/T cg01061890 chr16:11836724 TXNDC11 -0.65 -10.47 -0.49 1.97e-22 Rheumatoid arthritis; LIHC cis rs250677 0.798 rs11168080 chr5:148409821 C/T cg18129178 chr5:148520854 ABLIM3 -0.47 -6.06 -0.31 3.67e-9 Breast cancer; LIHC trans rs2749592 0.531 rs994804 chr10:37900140 A/C cg17830980 chr10:43048298 ZNF37B 0.42 7.94 0.39 3.02e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs858239 0.730 rs858289 chr7:23248158 C/T cg18081818 chr7:23246105 NA -0.47 -7.16 -0.36 5.03e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs7568498 0.517 rs197261 chr2:161904823 A/G cg22496339 chr2:162101262 NA -0.51 -6.8 -0.35 4.66e-11 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC cis rs473651 0.901 rs563282 chr2:239329736 T/C cg01753270 chr2:239240285 TRAF3IP1 0.32 6.19 0.32 1.71e-9 Multiple system atrophy; LIHC cis rs739401 0.572 rs389285 chr11:3062673 G/A cg05729581 chr11:3078854 CARS -0.45 -6.14 -0.32 2.23e-9 Longevity; LIHC cis rs9814567 1.000 rs9968172 chr3:134231251 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.33 0.55 3.6e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs208520 0.690 rs2208442 chr6:66867004 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.23 -0.41 3.95e-15 Exhaled nitric oxide output; LIHC cis rs4555082 0.789 rs2816649 chr14:105708326 A/G cg13114125 chr14:105738426 BRF1 -0.73 -10.33 -0.49 6.14e-22 Mean platelet volume;Platelet distribution width; LIHC cis rs9303401 0.592 rs12936771 chr17:56725052 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs77741769 0.529 rs2047568 chr12:121243790 A/G cg02419362 chr12:121203948 SPPL3 -0.34 -5.91 -0.3 8.51e-9 Mean corpuscular volume; LIHC trans rs61931739 0.500 rs11513287 chr12:34584351 G/A cg26384229 chr12:38710491 ALG10B 0.79 9.48 0.46 4.5e-19 Morning vs. evening chronotype; LIHC cis rs4742903 0.935 rs7026246 chr9:106955686 A/C cg14250997 chr9:106856677 SMC2 0.36 6.07 0.31 3.36e-9 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15636057 chr19:36119798 RBM42 0.44 6.28 0.32 1e-9 Lung function (FEV1/FVC); LIHC cis rs5770917 1.000 rs8137478 chr22:51017296 G/C cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.44 -6.44 -0.33 4.11e-10 Narcolepsy; LIHC cis rs763121 0.853 rs3747172 chr22:39067524 A/G cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs4727027 0.625 rs75129390 chr7:148846775 T/A cg23583168 chr7:148888333 NA -0.72 -10.18 -0.48 1.95e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs3762637 1.000 rs16845530 chr3:122142447 T/C cg24169773 chr3:122142474 KPNA1 -0.48 -9.49 -0.46 4.19e-19 LDL cholesterol levels; LIHC cis rs9341808 0.527 rs2505946 chr6:80810683 A/G cg08355045 chr6:80787529 NA 0.38 7.96 0.4 2.58e-14 Sitting height ratio; LIHC cis rs904251 0.861 rs1757169 chr6:37487076 G/T cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.47e-9 Cognitive performance; LIHC cis rs61990749 0.597 rs10142722 chr14:78275549 A/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.44 -6.65 -0.34 1.17e-10 Fibroblast growth factor basic levels; LIHC cis rs965469 1.000 rs6051737 chr20:3296992 G/A cg25506879 chr20:3388711 C20orf194 -0.55 -6.74 -0.34 6.9e-11 IFN-related cytopenia; LIHC cis rs10751667 0.643 rs11246362 chr11:969818 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg13877915 chr19:58951672 ZNF132 -0.62 -10.68 -0.5 3.61e-23 Uric acid clearance; LIHC cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.65e-9 Menopause (age at onset); LIHC cis rs1348850 0.668 rs4893972 chr2:178496874 T/C cg27490568 chr2:178487706 NA 0.72 9.46 0.46 5.29e-19 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs17376456 0.825 rs28645862 chr5:93233128 G/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16600020 chr8:30210405 NA -0.29 -6.28 -0.32 1e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10789491 0.951 rs35050319 chr1:47103886 C/A cg15501359 chr1:47185051 KIAA0494 -0.8 -10.9 -0.51 6.16e-24 Response to hepatitis C treatment; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg06873352 chr17:61820015 STRADA 0.75 13.7 0.6 2.43e-34 Prudent dietary pattern; LIHC cis rs780094 0.585 rs3739095 chr2:27556721 C/T cg22903471 chr2:27725779 GCKR -0.44 -7.56 -0.38 3.68e-13 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs7552404 1.000 rs7524467 chr1:76194054 C/G cg22875332 chr1:76189707 ACADM 0.47 6.94 0.35 1.93e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7116495 0.609 rs11235444 chr11:71831859 G/A cg10381502 chr11:71823885 C11orf51 1.06 9.3 0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06116397 chr18:32820960 ZNF397 0.45 6.37 0.33 6.03e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs400736 0.602 rs4601608 chr1:8168808 A/G cg25007680 chr1:8021821 PARK7 -0.53 -8.01 -0.4 1.82e-14 Response to antidepressants and depression; LIHC cis rs3806843 0.735 rs2563335 chr5:140044292 A/C cg16179182 chr5:140090404 VTRNA1-1 -0.39 -6.44 -0.33 4.01e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs6754311 0.608 rs3739020 chr2:136602491 T/G cg07169764 chr2:136633963 MCM6 0.76 11.62 0.53 1.63e-26 Mosquito bite size; LIHC cis rs12478296 1.000 rs12474070 chr2:243039738 C/T cg18898632 chr2:242989856 NA -0.58 -7.84 -0.39 5.85e-14 Obesity-related traits; LIHC cis rs9814567 1.000 rs13059720 chr3:134242021 T/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs35110281 0.715 rs2838320 chr21:44995037 A/G cg01579765 chr21:45077557 HSF2BP -0.37 -6.85 -0.35 3.36e-11 Mean corpuscular volume; LIHC cis rs12477438 0.798 rs13409996 chr2:99575497 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.07 -14.82 -0.63 1.03e-38 Chronic sinus infection; LIHC cis rs5769765 0.773 rs11090920 chr22:50320105 A/G cg26441486 chr22:50317300 CRELD2 0.4 6.7 0.34 8.43e-11 Schizophrenia; LIHC cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.98 0.44 1.78e-17 Platelet count; LIHC cis rs7772486 0.658 rs4895683 chr6:146113654 T/A cg05347473 chr6:146136440 FBXO30 -0.36 -5.81 -0.3 1.45e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs752010 0.806 rs10890148 chr1:42091517 T/C cg06885757 chr1:42089581 HIVEP3 0.28 5.77 0.3 1.82e-8 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs2404602 0.692 rs7174673 chr15:77071998 T/C cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.96e-38 Blood metabolite levels; LIHC cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg08677398 chr8:58056175 NA 0.36 6.22 0.32 1.41e-9 Developmental language disorder (linguistic errors); LIHC cis rs79149102 0.579 rs3910748 chr15:75318652 A/G cg16226627 chr15:75307476 SCAMP5 0.54 9.88 0.47 2.04e-20 Lung cancer; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.86e-9 Total body bone mineral density; LIHC trans rs1814175 0.754 rs28593359 chr11:50042357 C/T cg03929089 chr4:120376271 NA -0.89 -18.71 -0.71 2.82e-54 Height; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg01172114 chr10:5979283 FBXO18 0.41 6.05 0.31 3.76e-9 Bilirubin levels; LIHC cis rs769267 0.895 rs1000237 chr19:19518316 T/A cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.13 0.4 7.99e-15 Tonsillectomy; LIHC cis rs7131987 0.718 rs7976961 chr12:29463088 C/T cg00204748 chr12:29376779 FAR2 0.4 7.43 0.37 8.63e-13 QT interval; LIHC cis rs796364 0.806 rs79725795 chr2:201083534 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -8.18 -0.4 5.8e-15 Schizophrenia; LIHC cis rs7917772 0.512 rs11594073 chr10:104308193 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.66 -0.38 1.95e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2573652 0.722 rs11636084 chr15:100543394 A/G cg09918751 chr15:100517450 ADAMTS17 -0.69 -11.97 -0.54 8.3e-28 Height; LIHC cis rs929354 0.772 rs2301916 chr7:156974127 G/T cg17757837 chr7:157058334 UBE3C 0.74 12.09 0.55 2.85e-28 Body mass index; LIHC cis rs875971 1.000 rs2420820 chr7:66091907 T/C cg18876405 chr7:65276391 NA -0.34 -6.16 -0.32 2.06e-9 Aortic root size; LIHC cis rs2439831 0.702 rs495175 chr15:43798684 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.66 9.24 0.45 2.79e-18 Lung cancer in ever smokers; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg01809437 chr16:84695622 KLHL36 0.43 6.71 0.34 7.89e-11 Bipolar disorder; LIHC cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.99 9.3 0.45 1.65e-18 Platelet count; LIHC cis rs367615 0.537 rs17161729 chr5:108660528 C/G cg17395555 chr5:108820864 NA -0.29 -6.2 -0.32 1.65e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg00684032 chr4:1343700 KIAA1530 0.52 7.57 0.38 3.51e-13 Obesity-related traits; LIHC cis rs35110281 0.693 rs3819161 chr21:45092653 A/G cg04455712 chr21:45112962 RRP1B 0.54 8.84 0.43 5.31e-17 Mean corpuscular volume; LIHC cis rs921968 0.541 rs3770213 chr2:219508372 A/T cg02985541 chr2:219472218 PLCD4 -0.42 -6.59 -0.34 1.66e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2717559 0.542 rs34147336 chr8:143884869 A/G cg06565975 chr8:143823917 SLURP1 -0.39 -6.44 -0.33 4.01e-10 Urinary tract infection frequency; LIHC cis rs1953600 0.645 rs2819945 chr10:81952956 G/A cg27417294 chr10:81904244 PLAC9 -0.36 -6.16 -0.32 2.04e-9 Sarcoidosis; LIHC cis rs4808199 0.947 rs2163804 chr19:19575965 G/A cg21559469 chr19:19431446 KIAA0892;SF4 0.42 5.73 0.3 2.21e-8 Nonalcoholic fatty liver disease; LIHC cis rs700651 0.789 rs882954 chr2:198907444 A/G cg10820045 chr2:198174542 NA 0.44 6.48 0.33 3.27e-10 Intracranial aneurysm; LIHC cis rs6066825 0.644 rs6125442 chr20:47331210 C/G cg18078177 chr20:47281410 PREX1 0.41 6.66 0.34 1.09e-10 Colorectal cancer; LIHC trans rs801193 0.613 rs2016325 chr7:66323500 T/C cg18876405 chr7:65276391 NA -0.45 -7.05 -0.36 1.01e-11 Aortic root size; LIHC cis rs1267303 0.642 rs116078607 chr1:46999238 G/A cg25110126 chr1:46999211 NA 0.48 6.48 0.33 3.12e-10 Monobrow; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg16103275 chr6:290800 DUSP22 0.5 6.64 0.34 1.21e-10 Menopause (age at onset); LIHC cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg07061783 chr6:25882402 NA -0.49 -6.93 -0.35 2.06e-11 Blood metabolite levels; LIHC cis rs2153535 0.601 rs9502719 chr6:8541032 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.58e-15 Motion sickness; LIHC cis rs897984 0.520 rs4889534 chr16:30865440 T/C cg02466173 chr16:30829666 NA 0.48 7.23 0.36 3.15e-12 Dementia with Lewy bodies; LIHC cis rs6754311 0.731 rs2164210 chr2:136580287 T/C cg15123519 chr2:136567270 LCT 0.45 9.45 0.45 5.65e-19 Mosquito bite size; LIHC cis rs2191566 0.845 rs7258517 chr19:44535999 G/T cg20607764 chr19:44506953 ZNF230 -0.42 -6.81 -0.35 4.5e-11 Acute lymphoblastic leukemia (childhood); LIHC trans rs916888 0.773 rs169201 chr17:44790203 A/G cg22968622 chr17:43663579 NA 1.18 12.9 0.57 2.59e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7843479 1.000 rs10503715 chr8:21850687 G/A cg17168535 chr8:21777572 XPO7 0.4 6.52 0.33 2.6e-10 Mean corpuscular volume; LIHC cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg13152130 chr6:118910203 C6orf204 -0.61 -6.58 -0.34 1.81e-10 Diastolic blood pressure; LIHC cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.1 -0.48 3.53e-21 Platelet count; LIHC cis rs9399135 0.967 rs2327578 chr6:135329969 C/T cg22676075 chr6:135203613 NA 0.38 6.24 0.32 1.32e-9 Red blood cell count; LIHC cis rs897984 0.806 rs1046276 chr16:30914626 A/G cg02466173 chr16:30829666 NA 0.44 7.25 0.37 2.79e-12 Dementia with Lewy bodies; LIHC cis rs1059312 0.771 rs7974764 chr12:129296588 G/C cg09035930 chr12:129282057 SLC15A4 0.6 11.2 0.52 5.04e-25 Systemic lupus erythematosus; LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg24503407 chr1:205819492 PM20D1 0.89 13.27 0.58 1.09e-32 Menarche (age at onset); LIHC cis rs11105298 0.891 rs11105325 chr12:89938590 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.36 -0.37 1.39e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs743757 1.000 rs2298955 chr3:50431194 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.45 -6.91 -0.35 2.43e-11 Diastolic blood pressure; LIHC cis rs10078 0.571 rs2241597 chr5:480509 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.71 9.53 0.46 2.9e-19 Fat distribution (HIV); LIHC cis rs4819052 0.679 rs2838860 chr21:46684904 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.51 7.44 0.37 8.21e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs918629 0.599 rs4563648 chr5:95265556 G/A cg10483112 chr5:95245456 ELL2 -0.39 -7.05 -0.36 9.91e-12 IgG glycosylation; LIHC cis rs1152591 0.543 rs1152590 chr14:64681193 C/T cg21174375 chr14:64681225 SYNE2 0.41 6.62 0.34 1.42e-10 Atrial fibrillation; LIHC cis rs9733 0.596 rs12089731 chr1:150647798 T/C cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs7659604 0.540 rs11724322 chr4:122697850 A/T cg19671926 chr4:122722719 EXOSC9 0.53 8.4 0.41 1.22e-15 Type 2 diabetes; LIHC cis rs10911232 0.507 rs10911196 chr1:182995233 G/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs2836950 0.545 rs2836922 chr21:40516308 C/T cg06238570 chr21:40685208 BRWD1 -0.37 -5.84 -0.3 1.24e-8 Menarche (age at onset); LIHC cis rs4653767 0.573 rs708772 chr1:226912891 A/G cg05262829 chr1:226921576 ITPKB 0.4 8.25 0.41 3.49e-15 Parkinson's disease; LIHC cis rs743757 1.000 rs743857 chr3:50493550 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.4 0.37 1.07e-12 Diastolic blood pressure; LIHC cis rs2574704 0.962 rs11709778 chr3:11652034 C/T cg15876825 chr3:11651881 VGLL4 -0.5 -8.2 -0.41 4.88e-15 Body mass index; LIHC cis rs6867032 0.917 rs4975719 chr5:2010162 C/T cg26168224 chr5:2018326 NA 0.24 5.89 0.3 9.02e-9 Gut microbiome composition (winter); LIHC cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.17 0.52 6.66e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3736594 0.918 rs9677663 chr2:27972445 G/A cg27432699 chr2:27873401 GPN1 -0.44 -6.9 -0.35 2.49e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6951245 0.580 rs10257426 chr7:1213694 G/A cg03188948 chr7:1209495 NA 0.57 6.14 0.31 2.34e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7193541 0.694 rs8061942 chr16:74691362 C/T cg01733217 chr16:74700730 RFWD3 0.92 22.83 0.78 9.57e-71 Multiple myeloma; LIHC cis rs477692 0.935 rs568918 chr10:131414455 A/G cg19680672 chr10:131412579 MGMT -0.42 -6.42 -0.33 4.45e-10 Response to temozolomide; LIHC trans rs2727020 0.729 rs1917325 chr11:49370004 G/A cg03929089 chr4:120376271 NA -0.84 -15.18 -0.63 3.71e-40 Coronary artery disease; LIHC cis rs7095607 0.630 rs10998012 chr10:69958690 A/G cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.66e-9 Lung function (FVC); LIHC cis rs1707322 0.721 rs61784800 chr1:46178112 A/G cg03146154 chr1:46216737 IPP -0.59 -10.17 -0.48 2.07e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs66782572 1 rs66782572 chr3:52567617 A/G cg05564831 chr3:52568323 NT5DC2 0.35 6.0 0.31 5.09e-9 Hemoglobin concentration; LIHC trans rs4566357 0.615 rs10190621 chr2:227914484 A/G cg16088116 chr21:44841560 SIK1 -0.4 -6.07 -0.31 3.39e-9 Coronary artery disease; LIHC cis rs9902453 1.000 rs6505158 chr17:28403348 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.68 -0.53 9.33e-27 Coffee consumption (cups per day); LIHC cis rs2933343 0.649 rs2638845 chr3:128587369 A/G cg25356066 chr3:128598488 ACAD9 0.55 7.67 0.38 1.82e-13 IgG glycosylation; LIHC cis rs7267979 0.932 rs417130 chr20:25458320 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.8 0.35 4.7e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7707921 0.881 rs1428940 chr5:81447995 A/G cg15871215 chr5:81402204 ATG10 -0.63 -6.25 -0.32 1.26e-9 Breast cancer; LIHC cis rs372883 0.648 rs15092 chr21:30718201 G/A cg24692254 chr21:30365293 RNF160 -0.49 -6.17 -0.32 1.97e-9 Pancreatic cancer; LIHC cis rs16854884 0.584 rs2164554 chr3:143755528 A/G cg06585982 chr3:143692056 C3orf58 0.49 6.08 0.31 3.23e-9 Economic and political preferences (feminism/equality); LIHC cis rs875971 1.000 rs2042133 chr7:65931922 A/G cg11764359 chr7:65958608 NA 0.88 15.8 0.65 1.25e-42 Aortic root size; LIHC cis rs9814567 0.574 rs7650509 chr3:134170971 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.4 7.25 0.36 2.83e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs904251 0.861 rs2776875 chr6:37486796 G/C cg01843034 chr6:37503916 NA -0.46 -7.24 -0.36 3.01e-12 Cognitive performance; LIHC cis rs7224737 1.000 rs9915255 chr17:40284191 C/T cg02450064 chr17:40260053 DHX58 -0.28 -5.75 -0.3 1.95e-8 Fibrinogen levels; LIHC cis rs2549003 1.000 rs2549004 chr5:131827825 C/G cg21138405 chr5:131827807 IRF1 -0.4 -10.54 -0.5 1.08e-22 Asthma (sex interaction); LIHC cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs798554 0.797 rs35957220 chr7:2812632 C/G cg19717773 chr7:2847554 GNA12 -0.41 -6.64 -0.34 1.25e-10 Height; LIHC cis rs9549328 0.800 rs9549621 chr13:113633579 G/A cg18289306 chr13:113640169 MCF2L 0.41 6.58 0.34 1.75e-10 Systolic blood pressure; LIHC cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg06481639 chr22:41940642 POLR3H 0.66 6.95 0.35 1.9e-11 Vitiligo; LIHC cis rs3806843 1.000 rs4151680 chr5:140186657 A/G cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg05368731 chr17:41323189 NBR1 0.72 12.06 0.55 3.69e-28 Menopause (age at onset); LIHC trans rs11148252 0.574 rs3742297 chr13:53278067 T/C cg18335740 chr13:41363409 SLC25A15 0.55 10.04 0.48 5.92e-21 Lewy body disease; LIHC cis rs853679 0.517 rs9393887 chr6:28059020 G/A cg16479474 chr6:28041457 NA 0.46 6.76 0.34 5.91e-11 Depression; LIHC cis rs7927592 0.913 rs2282563 chr11:68333200 C/T cg16797656 chr11:68205561 LRP5 0.5 7.82 0.39 6.67e-14 Total body bone mineral density; LIHC cis rs6461049 0.765 rs1476887 chr7:2151633 T/C cg21782813 chr7:2030301 MAD1L1 0.36 6.09 0.31 3.06e-9 Schizophrenia; LIHC cis rs916888 0.821 rs199509 chr17:44858728 G/A cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs12744310 0.943 rs35972058 chr1:41769146 G/A cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7677751 0.806 rs4864862 chr4:55100489 G/A cg17187183 chr4:55093834 PDGFRA 0.68 8.49 0.42 6.36e-16 Corneal astigmatism; LIHC cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg22105103 chr4:187893119 NA 0.34 8.48 0.42 7.07e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs3749237 0.595 rs11130192 chr3:49467206 C/G cg06212747 chr3:49208901 KLHDC8B 0.47 6.12 0.31 2.51e-9 Resting heart rate; LIHC cis rs6456156 0.586 rs7746628 chr6:167483235 A/G cg12798992 chr6:167411361 FGFR1OP 0.44 6.65 0.34 1.13e-10 Primary biliary cholangitis; LIHC cis rs6960043 0.936 rs62448618 chr7:15052211 T/A cg19272540 chr7:15055459 NA -0.22 -6.23 -0.32 1.35e-9 Type 2 diabetes; LIHC cis rs6831352 0.918 rs4699712 chr4:100060490 A/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC trans rs7618501 1.000 rs1049256 chr3:49763338 T/C cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC trans rs10847980 0.623 rs7955367 chr12:123828792 G/A cg07919128 chr17:18022025 MYO15A -0.75 -7.58 -0.38 3.33e-13 Adiponectin levels; LIHC trans rs2727020 0.658 rs10839269 chr11:49385596 A/G cg03929089 chr4:120376271 NA -0.86 -16.26 -0.66 1.94e-44 Coronary artery disease; LIHC trans rs1814175 0.645 rs28441045 chr11:50048971 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs7769051 1.000 rs12204027 chr6:133122831 A/G cg07930552 chr6:133119739 C6orf192 0.68 6.42 0.33 4.65e-10 Type 2 diabetes nephropathy; LIHC cis rs35110281 0.626 rs162389 chr21:44936227 T/C cg04455712 chr21:45112962 RRP1B 0.42 7.15 0.36 5.45e-12 Mean corpuscular volume; LIHC cis rs1577917 0.958 rs11755864 chr6:86691791 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.54 -9.58 -0.46 2.11e-19 Response to antipsychotic treatment; LIHC cis rs10876993 0.928 rs1678530 chr12:58054076 A/C cg15848620 chr12:58087721 OS9 -0.55 -7.47 -0.37 6.68e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs599083 0.530 rs491347 chr11:68169688 G/A cg01657329 chr11:68192670 LRP5 0.58 7.85 0.39 5.26e-14 Bone mineral density (spine); LIHC cis rs921968 0.643 rs612874 chr2:219492924 T/C cg02985541 chr2:219472218 PLCD4 0.44 8.13 0.4 7.89e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs9611519 0.929 rs2064560 chr22:41530040 A/G cg03806693 chr22:41940476 POLR3H -0.68 -7.32 -0.37 1.79e-12 Neuroticism; LIHC cis rs4589502 0.841 rs55855162 chr15:67140523 C/A cg12317470 chr15:67143691 NA 0.58 5.94 0.31 7.01e-9 Lung cancer (smoking interaction); LIHC cis rs875971 0.862 rs7809814 chr7:65615397 G/A cg18876405 chr7:65276391 NA -0.37 -6.61 -0.34 1.45e-10 Aortic root size; LIHC trans rs6489882 0.703 rs2057778 chr12:113350796 A/C cg10175203 chr3:128143634 NA -0.38 -6.28 -0.32 1.03e-9 Chronic lymphocytic leukemia; LIHC cis rs9549367 0.737 rs71446680 chr13:113894846 C/T cg18105134 chr13:113819100 PROZ -0.66 -11.47 -0.53 5.42e-26 Platelet distribution width; LIHC trans rs526821 0.595 rs2926309 chr11:55314219 G/A cg03929089 chr4:120376271 NA -0.45 -6.8 -0.35 4.63e-11 Pediatric bone mineral density (spine); LIHC cis rs1843834 0.755 rs11898692 chr2:225575173 T/C cg22509189 chr2:225307070 NA -0.45 -5.75 -0.3 2.02e-8 IgE levels in asthmatics (D.p. specific); LIHC cis rs2228479 0.850 rs17226428 chr16:89842884 T/A cg00800038 chr16:89945340 TCF25 -0.64 -9.34 -0.45 1.31e-18 Skin colour saturation; LIHC cis rs4820539 1.000 rs4822357 chr22:23473231 A/G cg21100191 chr22:23484243 RTDR1 0.83 14.57 0.62 9.76e-38 Bone mineral density; LIHC cis rs7552404 1.000 rs4559448 chr1:76203456 A/G cg03433033 chr1:76189801 ACADM 0.63 8.73 0.43 1.14e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg18306943 chr3:40428807 ENTPD3 0.44 7.6 0.38 2.84e-13 Renal cell carcinoma; LIHC cis rs4780401 0.609 rs4780399 chr16:11828701 A/T cg01061890 chr16:11836724 TXNDC11 -0.64 -10.28 -0.49 9.19e-22 Rheumatoid arthritis; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg23131131 chr22:24373011 LOC391322 -0.53 -7.36 -0.37 1.42e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs875971 0.651 rs2420596 chr7:65915983 T/C cg18876405 chr7:65276391 NA 0.37 6.68 0.34 9.57e-11 Aortic root size; LIHC cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 6.02e-12 Diabetic kidney disease; LIHC cis rs4919694 1.000 rs77969925 chr10:104649357 C/T cg04362960 chr10:104952993 NT5C2 0.77 7.61 0.38 2.65e-13 Arsenic metabolism; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg03479204 chr13:114193155 TMCO3 -0.42 -6.69 -0.34 9.25e-11 Pain; LIHC cis rs965469 0.857 rs1922990 chr20:3252348 G/A cg25506879 chr20:3388711 C20orf194 -0.52 -6.46 -0.33 3.58e-10 IFN-related cytopenia; LIHC cis rs1348850 0.526 rs4893829 chr2:178399810 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.66 -5.8 -0.3 1.5e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7572733 0.555 rs11889006 chr2:198928647 A/G cg10820045 chr2:198174542 NA 0.42 6.33 0.32 7.54e-10 Dermatomyositis; LIHC cis rs769267 0.930 rs1047361 chr19:19606634 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.34 0.32 7.45e-10 Tonsillectomy; LIHC cis rs4742903 0.875 rs4543600 chr9:106939884 A/G cg14250997 chr9:106856677 SMC2 0.35 5.92 0.3 7.8e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2243480 1.000 rs778679 chr7:65840911 A/G cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC cis rs782590 0.643 rs13009906 chr2:55739434 A/G cg03859395 chr2:55845619 SMEK2 -0.48 -7.93 -0.39 3.11e-14 Metabolic syndrome; LIHC cis rs10876993 0.890 rs12302350 chr12:58062589 T/G cg15848620 chr12:58087721 OS9 -0.53 -7.14 -0.36 5.69e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg12463550 chr7:65579703 CRCP 0.69 7.12 0.36 6.23e-12 Diabetic kidney disease; LIHC cis rs35883536 0.935 rs1106347 chr1:101149059 A/T cg14515779 chr1:101123966 NA -0.69 -13.89 -0.6 4.36e-35 Monocyte count; LIHC cis rs716804 0.598 rs10840381 chr11:10297957 A/C cg01453529 chr11:10209919 SBF2 -0.29 -5.86 -0.3 1.11e-8 Neuroticism; LIHC cis rs2304069 0.954 rs2276983 chr5:149424966 C/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.79 10.11 0.48 3.45e-21 HIV-1 control; LIHC cis rs11690935 0.798 rs13018768 chr2:172598592 A/G cg13550731 chr2:172543902 DYNC1I2 -0.92 -17.66 -0.69 4.41e-50 Schizophrenia; LIHC cis rs12701220 0.522 rs12334290 chr7:1054517 A/G cg26769984 chr7:1090371 C7orf50 0.46 6.28 0.32 1.01e-9 Bronchopulmonary dysplasia; LIHC cis rs4727027 0.933 rs9718383 chr7:148857624 A/T cg23583168 chr7:148888333 NA 0.74 10.55 0.5 1.04e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs4423214 1.000 rs4944958 chr11:71168073 A/G cg24826892 chr11:71159390 DHCR7 0.48 6.15 0.32 2.21e-9 Vitamin D levels; LIHC cis rs875971 0.545 rs10950025 chr7:65623933 G/A cg11764359 chr7:65958608 NA 0.51 7.08 0.36 8.1e-12 Aortic root size; LIHC cis rs1577917 1.000 rs12190604 chr6:86716215 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -9.84 -0.47 2.74e-20 Response to antipsychotic treatment; LIHC cis rs7394579 1 rs7394579 chr11:61581450 A/G cg27386326 chr11:61587980 NA 0.67 13.45 0.59 2.07e-33 Red cell distribution width;Mean platelet volume; LIHC cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.57 -5.84 -0.3 1.22e-8 Diastolic blood pressure; LIHC cis rs7772486 0.790 rs2249386 chr6:146186611 G/A cg23711669 chr6:146136114 FBXO30 0.72 13.13 0.58 3.64e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs7106204 0.514 rs12293105 chr11:24256048 T/C ch.11.24196551F chr11:24239977 NA 0.84 12.17 0.55 1.5e-28 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4934494 0.813 rs12775783 chr10:91406251 G/A cg19698084 chr10:91461284 KIF20B -0.5 -6.53 -0.33 2.45e-10 Red blood cell count; LIHC cis rs1371867 0.846 rs2439458 chr8:101297984 T/C cg06636551 chr8:101224915 SPAG1 -0.48 -8.9 -0.43 3.31e-17 Atrioventricular conduction; LIHC cis rs8027181 0.839 rs998020 chr15:72999635 C/T cg03441853 chr15:73075003 ADPGK 0.29 5.99 0.31 5.23e-9 Triglyceride levels; LIHC cis rs172166 0.637 rs1233691 chr6:28153897 T/G cg23485639 chr6:28045615 ZNF165 0.38 6.0 0.31 5.1e-9 Cardiac Troponin-T levels; LIHC cis rs7833986 0.501 rs2976036 chr8:57031721 G/T cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.63 0.42 2.28e-16 Height; LIHC cis rs2573652 1.000 rs2581345 chr15:100514291 A/G cg09918751 chr15:100517450 ADAMTS17 -0.8 -14.47 -0.62 2.43e-37 Height; LIHC cis rs4407350 0.655 rs135623 chr22:44890672 C/T cg11695653 chr22:44894386 LDOC1L -0.36 -6.17 -0.32 1.94e-9 Intelligence (multi-trait analysis); LIHC cis rs7474896 0.537 rs2505255 chr10:38359642 C/A cg25427524 chr10:38739819 LOC399744 -0.45 -5.74 -0.3 2.09e-8 Obesity (extreme); LIHC cis rs11671005 0.735 rs11668814 chr19:58946833 T/C cg25952890 chr19:58913133 NA 0.7 7.64 0.38 2.23e-13 Mean platelet volume; LIHC cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg02475777 chr4:1388615 CRIPAK 0.4 6.48 0.33 3.3e-10 Obesity-related traits; LIHC cis rs4819052 0.765 rs2838854 chr21:46680364 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.76 0.39 9.59e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24583131 chr6:18265189 DEK 0.44 6.17 0.32 1.91e-9 Pancreatic cancer; LIHC cis rs4819052 1.000 rs4818769 chr21:46667451 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.71 9.47 0.46 4.6e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg26116260 chr4:7069785 GRPEL1 0.99 18.17 0.7 3.94e-52 Monocyte percentage of white cells; LIHC cis rs9549367 0.713 rs9549356 chr13:113851633 A/G cg00898013 chr13:113819073 PROZ -0.47 -7.78 -0.39 8.51e-14 Platelet distribution width; LIHC cis rs10193935 0.901 rs17029344 chr2:42444287 T/C cg27598129 chr2:42591480 NA -0.72 -11.12 -0.52 9.97e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs55665837 0.540 rs11023302 chr11:14693935 C/G cg25251204 chr11:14927456 NA 0.41 5.87 0.3 1.03e-8 Vitamin D levels; LIHC cis rs9649213 0.574 rs3801257 chr7:97991792 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.91 -0.3 8.06e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs2976388 0.566 rs2585141 chr8:143806343 G/A cg06565975 chr8:143823917 SLURP1 -0.44 -8.01 -0.4 1.84e-14 Urinary tract infection frequency; LIHC cis rs807029 0.533 rs735137 chr10:102735835 C/G cg25179470 chr10:102756915 LZTS2 0.46 6.46 0.33 3.51e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs9929218 1.000 rs67359183 chr16:68814204 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.61 -0.42 2.81e-16 Colorectal cancer; LIHC cis rs9300255 0.596 rs10734900 chr12:123743445 G/A cg00376283 chr12:123451042 ABCB9 0.65 9.87 0.47 2.22e-20 Neutrophil percentage of white cells; LIHC cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg07414643 chr4:187882934 NA -0.23 -5.71 -0.3 2.44e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7193541 0.684 rs4887783 chr16:74700743 G/C cg01733217 chr16:74700730 RFWD3 0.97 24.93 0.8 6.49e-79 Multiple myeloma; LIHC cis rs4638749 0.588 rs13401731 chr2:108885340 C/T cg25838818 chr2:108905173 SULT1C2 -0.47 -8.42 -0.41 1.09e-15 Blood pressure; LIHC cis rs939574 0.512 rs55908154 chr2:220145960 G/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.59 7.08 0.36 8.04e-12 Platelet distribution width; LIHC cis rs9902453 0.584 rs3809790 chr17:27955540 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.59 -0.53 2.07e-26 Coffee consumption (cups per day); LIHC cis rs9814567 0.752 rs4605591 chr3:134328361 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.72 -0.3 2.37e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9399135 0.660 rs4267967 chr6:135272477 T/G cg24558204 chr6:135376177 HBS1L 0.43 6.92 0.35 2.2e-11 Red blood cell count; LIHC cis rs4555082 0.874 rs113291192 chr14:105738181 C/T cg13114125 chr14:105738426 BRF1 -0.74 -9.74 -0.47 6.02e-20 Mean platelet volume;Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16031872 chr3:142297641 ATR 0.47 6.25 0.32 1.22e-9 Lung function (FEV1/FVC); LIHC cis rs947211 0.948 rs1775143 chr1:205755550 C/T cg14893161 chr1:205819251 PM20D1 0.33 5.74 0.3 2.11e-8 Parkinson's disease; LIHC cis rs922107 0.935 rs1077539 chr1:90013144 T/G cg15422784 chr1:90023713 LRRC8B -0.47 -7.66 -0.38 1.87e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC trans rs7618501 1.000 rs57648519 chr3:49813169 C/A cg21582582 chr3:182698605 DCUN1D1 0.53 6.89 0.35 2.76e-11 Intelligence (multi-trait analysis); LIHC cis rs6942756 0.806 rs6467237 chr7:128964831 A/G cg02491457 chr7:128862824 NA -0.57 -8.48 -0.42 6.79e-16 White matter hyperintensity burden; LIHC cis rs6840360 0.571 rs4696275 chr4:152530981 C/T cg22705602 chr4:152727874 NA -0.33 -6.41 -0.33 4.73e-10 Intelligence (multi-trait analysis); LIHC cis rs17106184 1.000 rs72898944 chr1:50958027 C/A cg07174182 chr1:51127561 FAF1 -0.59 -6.64 -0.34 1.23e-10 Type 2 diabetes; LIHC cis rs7224737 1.000 rs2285657 chr17:40272594 C/A cg00647820 chr17:40259828 DHX58 -0.29 -5.77 -0.3 1.79e-8 Fibrinogen levels; LIHC cis rs1348850 0.914 rs12104588 chr2:178253675 G/A cg27490568 chr2:178487706 NA 0.38 6.05 0.31 3.87e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs73206853 0.640 rs871921 chr12:111115113 G/C cg12870014 chr12:110450643 ANKRD13A 0.72 8.53 0.42 4.73e-16 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs7771547 0.573 rs544267 chr6:36398302 A/G cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Platelet distribution width; LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg02290350 chr8:58132656 NA 0.5 10.54 0.5 1.11e-22 Developmental language disorder (linguistic errors); LIHC cis rs11628318 0.614 rs10140498 chr14:103154191 A/G cg23461800 chr14:103021989 NA 0.46 6.34 0.32 7.13e-10 Platelet count; LIHC cis rs35306767 0.953 rs7908138 chr10:962978 C/T cg26597838 chr10:835615 NA 0.98 11.98 0.54 7.58e-28 Eosinophil percentage of granulocytes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00001245 chr3:15106710 MRPS25 0.51 6.55 0.33 2.15e-10 Lung function (FEV1/FVC); LIHC cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.49 7.03 0.36 1.13e-11 Schizophrenia; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg21131796 chr12:124829443 NCOR2 0.43 6.28 0.32 1.02e-9 Bilirubin levels; LIHC cis rs2549003 1.000 rs2548999 chr5:131831058 G/T cg02551604 chr5:131831745 NA 0.44 6.56 0.33 2e-10 Asthma (sex interaction); LIHC cis rs6840360 0.593 rs59350867 chr4:152695935 G/A cg22705602 chr4:152727874 NA -0.41 -8.68 -0.42 1.66e-16 Intelligence (multi-trait analysis); LIHC cis rs17818399 0.547 rs35178974 chr2:46763898 T/C cg02822958 chr2:46747628 ATP6V1E2 0.43 6.34 0.32 7.42e-10 Height; LIHC cis rs4713118 0.784 rs9468219 chr6:27731755 C/A cg20933634 chr6:27740509 NA 0.45 5.93 0.31 7.39e-9 Parkinson's disease; LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg10755058 chr3:40428713 ENTPD3 0.4 6.78 0.34 5.32e-11 Renal cell carcinoma; LIHC cis rs8053891 0.805 rs12149869 chr16:71995946 T/C cg01557791 chr16:72042693 DHODH -0.43 -6.24 -0.32 1.31e-9 Coronary artery disease; LIHC cis rs735396 1.000 rs1169309 chr12:121439192 G/T cg25281562 chr12:121454272 C12orf43 0.33 5.73 0.3 2.24e-8 N-glycan levels; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg19806062 chr19:11319688 DOCK6 0.47 7.16 0.36 4.98e-12 Alopecia areata; LIHC cis rs911119 0.955 rs67997662 chr20:23592864 G/A cg16589663 chr20:23618590 CST3 0.72 7.59 0.38 3.09e-13 Chronic kidney disease; LIHC cis rs7927771 0.524 rs11039377 chr11:47789776 C/T cg20307385 chr11:47447363 PSMC3 0.72 10.68 0.5 3.75e-23 Subjective well-being; LIHC cis rs12464559 0.649 rs11896217 chr2:152591189 G/A cg01189475 chr2:152685088 ARL5A 0.67 7.83 0.39 6.03e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs826838 0.933 rs980573 chr12:39127811 T/C cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs526821 0.595 rs551665 chr11:55343268 G/A cg04317927 chr11:55418816 OR4S2 0.47 8.98 0.44 1.87e-17 Pediatric bone mineral density (spine); LIHC cis rs12824058 0.831 rs4759452 chr12:130812799 G/A cg24838063 chr12:130822603 PIWIL1 0.67 9.86 0.47 2.31e-20 Menopause (age at onset); LIHC trans rs7618501 1.000 rs4855862 chr3:49748833 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg18306943 chr3:40428807 ENTPD3 0.42 7.41 0.37 9.68e-13 Renal cell carcinoma; LIHC cis rs919433 0.713 rs13411968 chr2:198467141 C/T cg03934865 chr2:198174659 NA 0.53 8.06 0.4 1.26e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9457247 0.602 rs13204839 chr6:167471119 G/A cg23791538 chr6:167370224 RNASET2 -0.52 -7.84 -0.39 5.63e-14 Crohn's disease; LIHC cis rs7640424 1.000 rs7640424 chr3:107820063 C/T cg09227934 chr3:107805635 CD47 -0.51 -6.0 -0.31 4.97e-9 Body mass index; LIHC cis rs7188861 1.000 rs7188861 chr16:11454650 C/A cg01510278 chr16:11456238 NA 0.5 6.07 0.31 3.37e-9 HDL cholesterol; LIHC cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.01 0.54 5.93e-28 Alzheimer's disease; LIHC cis rs7917772 0.582 rs10883753 chr10:104372441 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.67 0.38 1.85e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7945718 0.621 rs7939509 chr11:12688130 T/C cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs1552244 0.882 rs13064570 chr3:9997545 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.69 0.5 3.27e-23 Alzheimer's disease; LIHC cis rs2108622 0.668 rs62106153 chr19:15978507 C/T cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.87e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs2236267 0.564 rs8007372 chr14:88629117 C/T cg02175263 chr14:88627849 NA 0.37 6.82 0.35 4.14e-11 Food antigen IgG levels; LIHC cis rs12887734 0.524 rs4906364 chr14:104214342 C/G cg08213375 chr14:104286397 PPP1R13B 0.53 9.24 0.45 2.59e-18 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs6565180 0.926 rs8046445 chr16:30386262 A/G cg17640201 chr16:30407289 ZNF48 -0.78 -13.54 -0.59 9.39e-34 Tonsillectomy; LIHC cis rs4423214 1.000 rs4944956 chr11:71167765 C/T cg05163923 chr11:71159392 DHCR7 0.86 13.38 0.59 3.95e-33 Vitamin D levels; LIHC cis rs15676 0.783 rs10988119 chr9:131564585 T/C cg00228799 chr9:131580591 ENDOG -0.48 -6.8 -0.34 4.79e-11 Blood metabolite levels; LIHC cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg08888203 chr3:10149979 C3orf24 0.57 6.81 0.35 4.35e-11 Alzheimer's disease; LIHC cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs11702148 0.552 rs11701506 chr21:34904352 T/A cg14850771 chr21:34775459 IFNGR2 0.46 7.52 0.38 4.81e-13 Mean corpuscular hemoglobin; LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg21448741 chr8:58168803 NA 0.37 6.69 0.34 9.39e-11 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.862 rs10950043 chr7:65988610 T/C cg11764359 chr7:65958608 NA 0.78 13.62 0.59 4.71e-34 Aortic root size; LIHC trans rs783540 0.900 rs12916980 chr15:83306447 C/G cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.17 -0.32 1.9e-9 Schizophrenia; LIHC cis rs11031096 0.711 rs4910890 chr11:4153407 C/T cg18678763 chr11:4115507 RRM1 -0.58 -8.66 -0.42 1.92e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2806561 0.754 rs10917337 chr1:23300723 G/A cg19743168 chr1:23544995 NA -0.37 -6.88 -0.35 2.84e-11 Height; LIHC cis rs11148252 0.740 rs9596643 chr13:52912380 G/A cg00495681 chr13:53174319 NA -0.37 -5.81 -0.3 1.41e-8 Lewy body disease; LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg26939375 chr7:64535504 NA 0.47 8.25 0.41 3.36e-15 Calcium levels; LIHC cis rs6088590 0.610 rs6088461 chr20:32905161 G/T cg24642439 chr20:33292090 TP53INP2 0.61 7.52 0.38 4.99e-13 Coronary artery disease; LIHC cis rs57590327 0.503 rs7426937 chr3:81881360 T/C cg07356753 chr3:81810745 GBE1 -0.53 -8.11 -0.4 8.91e-15 Extraversion; LIHC cis rs9858542 1.000 rs3197999 chr3:49721532 G/A cg02487422 chr3:49467188 NICN1 -0.49 -6.34 -0.32 7.39e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9503598 0.517 rs11242860 chr6:3463536 A/C cg00476032 chr6:3446245 SLC22A23 0.42 7.94 0.39 2.91e-14 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs9790314 0.690 rs4679930 chr3:160842875 C/G cg03342759 chr3:160939853 NMD3 -0.72 -11.07 -0.51 1.46e-24 Morning vs. evening chronotype; LIHC trans rs208520 0.770 rs2153941 chr6:66885521 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.14 -0.4 7.54e-15 Exhaled nitric oxide output; LIHC cis rs10504229 0.636 rs10958525 chr8:58051528 C/A cg02290350 chr8:58132656 NA 0.32 7.05 0.36 9.69e-12 Developmental language disorder (linguistic errors); LIHC cis rs9399135 0.967 rs34546690 chr6:135369709 T/C cg22676075 chr6:135203613 NA 0.41 6.54 0.33 2.19e-10 Red blood cell count; LIHC cis rs9325144 0.560 rs1825802 chr12:38650341 C/T cg26384229 chr12:38710491 ALG10B -0.48 -7.41 -0.37 1.03e-12 Morning vs. evening chronotype; LIHC cis rs2439831 1.000 rs2601014 chr15:43756013 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.78 11.56 0.53 2.61e-26 Lung cancer in ever smokers; LIHC cis rs6570726 0.846 rs7762536 chr6:145923145 T/C cg13319975 chr6:146136371 FBXO30 -0.37 -5.89 -0.3 9.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs36051895 0.632 rs10974980 chr9:5140671 C/G cg02405213 chr9:5042618 JAK2 -0.65 -10.97 -0.51 3.54e-24 Pediatric autoimmune diseases; LIHC cis rs57590327 0.555 rs11127740 chr3:81743062 A/C cg07356753 chr3:81810745 GBE1 -0.53 -8.18 -0.4 5.65e-15 Extraversion; LIHC cis rs1707322 0.721 rs12091503 chr1:46107868 T/C cg03146154 chr1:46216737 IPP 0.57 9.9 0.47 1.78e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 1.000 rs6958484 chr7:65599446 G/A cg11764359 chr7:65958608 NA -0.87 -15.19 -0.63 3.51e-40 Aortic root size; LIHC cis rs8049603 1.000 rs35260685 chr16:23088062 C/A cg16484020 chr16:23217411 SCNN1G -0.25 -5.71 -0.3 2.44e-8 Multiple sclerosis; LIHC cis rs7412746 0.658 rs6656535 chr1:150940357 G/T cg18016565 chr1:150552671 MCL1 0.51 9.67 0.46 1.03e-19 Melanoma; LIHC cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg08888203 chr3:10149979 C3orf24 0.57 6.84 0.35 3.72e-11 Alzheimer's disease; LIHC cis rs3617 0.539 rs9880619 chr3:52953055 G/A cg11645453 chr3:52864694 ITIH4 -0.21 -5.75 -0.3 1.93e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs11864453 0.927 rs1035560 chr16:72032730 T/C cg01557791 chr16:72042693 DHODH -0.73 -11.45 -0.53 6.72e-26 Fibrinogen levels; LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs644799 1.000 rs693597 chr11:95589629 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.72 0.47 6.89e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9790314 0.690 rs7633857 chr3:160844942 C/G cg03342759 chr3:160939853 NMD3 -0.72 -11.07 -0.51 1.46e-24 Morning vs. evening chronotype; LIHC cis rs2239547 0.657 rs3755803 chr3:52866157 C/G cg11645453 chr3:52864694 ITIH4 0.35 8.97 0.44 2.05e-17 Schizophrenia; LIHC cis rs7224737 1.000 rs8074708 chr17:40286354 A/G cg02228675 chr17:40259724 DHX58 0.25 5.72 0.3 2.3e-8 Fibrinogen levels; LIHC cis rs7582720 1.000 rs6722332 chr2:203745327 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1789 0.903 rs4453929 chr4:15672173 T/G cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.86 -0.3 1.07e-8 Blood protein levels; LIHC cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg08392591 chr16:89556376 ANKRD11 0.57 8.98 0.44 1.84e-17 Multiple myeloma (IgH translocation); LIHC cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg08219700 chr8:58056026 NA 0.5 6.22 0.32 1.49e-9 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.868 rs2531352 chr5:140119534 A/G cg19875535 chr5:140030758 IK -0.36 -5.99 -0.31 5.28e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs17608059 0.566 rs17676459 chr17:13910515 A/G cg11395062 chr17:14139857 CDRT15 0.53 9.52 0.46 3.17e-19 Temperament; LIHC cis rs6570726 0.846 rs6570700 chr6:145931552 A/G cg23711669 chr6:146136114 FBXO30 0.61 10.49 0.49 1.6e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs172166 0.694 rs203877 chr6:28048624 T/C cg16479474 chr6:28041457 NA 0.39 6.68 0.34 9.98e-11 Cardiac Troponin-T levels; LIHC cis rs1005277 0.579 rs1780136 chr10:38501453 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7587476 0.601 rs17489231 chr2:215673739 T/G cg04004882 chr2:215674386 BARD1 -0.59 -8.34 -0.41 1.9e-15 Neuroblastoma; LIHC cis rs6539267 0.741 rs7314289 chr12:106686260 A/C cg02476566 chr12:106696527 TCP11L2 0.45 5.94 0.31 6.98e-9 Tourette syndrome; LIHC cis rs1865760 0.566 rs9295688 chr6:26084217 G/A cg18357526 chr6:26021779 HIST1H4A 0.45 6.54 0.33 2.22e-10 Height; LIHC cis rs9783347 1.000 rs1140047 chr11:18327684 G/T cg15585147 chr11:18324498 HPS5 0.44 6.81 0.35 4.35e-11 Pancreatic cancer; LIHC cis rs8014204 1.000 rs4553560 chr14:75334199 T/C cg08847533 chr14:75593920 NEK9 -0.37 -6.05 -0.31 3.78e-9 Caffeine consumption; LIHC cis rs2242116 0.743 rs11719795 chr3:46951935 T/C cg16586182 chr3:47516702 SCAP -0.38 -6.22 -0.32 1.48e-9 Birth weight; LIHC cis rs10256972 0.521 rs10280960 chr7:1103697 A/G cg07308232 chr7:1071921 C7orf50 -0.44 -6.8 -0.35 4.66e-11 Longevity;Endometriosis; LIHC cis rs11792861 0.816 rs2304779 chr9:111670513 C/T cg05043794 chr9:111880884 C9orf5 0.29 6.89 0.35 2.62e-11 Menarche (age at onset); LIHC cis rs7027203 0.828 rs4743934 chr9:96581893 A/G cg14396892 chr9:96623032 NA -0.31 -6.1 -0.31 2.81e-9 DNA methylation (variation); LIHC cis rs7187994 0.895 rs7184644 chr16:84786460 C/A cg07647771 chr16:84786436 USP10 -0.33 -6.36 -0.33 6.37e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs6500602 0.702 rs11645519 chr16:4538989 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.82 0.3 1.36e-8 Schizophrenia; LIHC cis rs16854884 0.632 rs1910691 chr3:143656905 G/A cg06585982 chr3:143692056 C3orf58 0.64 9.07 0.44 9.29e-18 Economic and political preferences (feminism/equality); LIHC cis rs7520050 0.645 rs1768809 chr1:46502836 A/C cg03146154 chr1:46216737 IPP -0.41 -6.87 -0.35 3.09e-11 Red blood cell count;Reticulocyte count; LIHC cis rs919433 0.679 rs13000656 chr2:198522126 T/C cg03934865 chr2:198174659 NA -0.47 -6.96 -0.35 1.79e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs600806 0.850 rs12073497 chr1:109974450 A/C cg23091122 chr1:110024289 SYPL2 -0.47 -6.18 -0.32 1.84e-9 Intelligence (multi-trait analysis); LIHC cis rs2651899 0.902 rs1624023 chr1:3079337 C/T cg22674798 chr1:3096360 PRDM16 0.28 6.93 0.35 2.09e-11 Migraine; LIHC trans rs7615952 0.515 rs7630575 chr3:125682330 A/G cg07211511 chr3:129823064 LOC729375 -0.57 -7.19 -0.36 4.22e-12 Blood pressure (smoking interaction); LIHC cis rs870825 0.860 rs72703529 chr4:185607351 T/C cg04058563 chr4:185651563 MLF1IP 0.84 6.96 0.35 1.73e-11 Blood protein levels; LIHC cis rs172166 0.694 rs1150666 chr6:28123928 T/C cg16479474 chr6:28041457 NA 0.38 6.44 0.33 4.05e-10 Cardiac Troponin-T levels; LIHC cis rs17401966 1.000 rs58053556 chr1:10442903 A/G cg19773385 chr1:10388646 KIF1B -0.47 -7.5 -0.38 5.62e-13 Hepatocellular carcinoma; LIHC cis rs644799 0.710 rs666398 chr11:95551136 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.64 0.56 2.6e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6912958 0.874 rs9294381 chr6:88152681 A/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.4 -7.1 -0.36 7.42e-12 Monocyte percentage of white cells; LIHC cis rs12995491 0.933 rs13008732 chr2:88528771 G/A cg14558114 chr2:88469736 THNSL2 -0.37 -5.77 -0.3 1.76e-8 Response to metformin (IC50); LIHC cis rs332507 0.830 rs2242425 chr3:124398644 A/G cg05980111 chr3:124395277 KALRN 0.46 7.07 0.36 8.83e-12 Plateletcrit; LIHC cis rs34172651 0.571 rs9922156 chr16:24704329 C/A cg00339695 chr16:24857497 SLC5A11 -0.48 -7.86 -0.39 4.91e-14 Intelligence (multi-trait analysis); LIHC cis rs611744 0.967 rs686630 chr8:109233239 G/C cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs4713118 0.824 rs742046 chr6:27739254 A/G cg20933634 chr6:27740509 NA 0.45 6.06 0.31 3.65e-9 Parkinson's disease; LIHC cis rs56235845 0.685 rs35630910 chr5:176757841 A/C cg16006841 chr5:176797999 RGS14 0.7 8.45 0.42 8.57e-16 Hemoglobin concentration;Hematocrit; LIHC cis rs8177179 0.570 rs4441652 chr3:133439450 A/G cg16262614 chr3:133464971 TF 0.43 6.82 0.35 4.04e-11 Iron status biomarkers (transferrin levels); LIHC trans rs1488564 1.000 rs1488564 chr3:173453868 A/G cg01198024 chr21:33672713 MRAP -0.42 -6.1 -0.31 2.88e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs8005677 0.962 rs34917191 chr14:23387628 T/C cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs2576037 0.526 rs8095373 chr18:44527895 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.68 10.72 0.5 2.54e-23 Personality dimensions; LIHC cis rs1008375 0.898 rs7678654 chr4:17575376 T/G cg16339924 chr4:17578868 LAP3 0.44 5.94 0.31 6.83e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4713118 0.824 rs7759217 chr6:27730463 A/G cg20933634 chr6:27740509 NA 0.45 5.93 0.31 7.39e-9 Parkinson's disease; LIHC cis rs2282802 0.685 rs12188849 chr5:139621570 G/A cg26211634 chr5:139558579 C5orf32 0.4 6.25 0.32 1.2e-9 Intelligence (multi-trait analysis); LIHC cis rs7666738 0.716 rs1426660 chr4:98876792 T/A cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg16145915 chr7:1198662 ZFAND2A -0.42 -11.52 -0.53 3.72e-26 Longevity;Endometriosis; LIHC cis rs7116495 0.786 rs10736782 chr11:71654012 A/G cg26138937 chr11:71823887 C11orf51 -0.67 -6.83 -0.35 3.88e-11 Severe influenza A (H1N1) infection; LIHC cis rs2012796 1.000 rs8008024 chr14:81818492 A/G cg02996355 chr14:81879375 NA 0.46 6.89 0.35 2.65e-11 Night sleep phenotypes; LIHC cis rs9649213 0.614 rs3801258 chr7:97988428 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.57 -10.09 -0.48 3.86e-21 Prostate cancer (SNP x SNP interaction); LIHC cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.53 -6.43 -0.33 4.38e-10 Diastolic blood pressure; LIHC cis rs2404602 0.716 rs2404737 chr15:76872217 T/G cg03037974 chr15:76606532 NA 0.75 14.71 0.62 2.68e-38 Blood metabolite levels; LIHC cis rs4908768 0.906 rs28422051 chr1:8618337 T/C cg25722041 chr1:8623473 RERE 0.43 6.06 0.31 3.55e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2731664 0.792 rs335466 chr5:176889530 C/A cg23176889 chr5:176863531 GRK6 -0.71 -12.28 -0.55 6.01e-29 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs4973878 chr3:40407565 C/T cg24209194 chr3:40518798 ZNF619 0.42 5.96 0.31 6.13e-9 Renal cell carcinoma; LIHC cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg19318889 chr4:1322082 MAEA 0.47 6.51 0.33 2.69e-10 Obesity-related traits; LIHC cis rs2153535 0.541 rs9328471 chr6:8468842 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs853679 0.517 rs9380065 chr6:28144751 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.75e-10 Depression; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg27432699 chr2:27873401 GPN1 -0.54 -7.82 -0.39 6.44e-14 Total body bone mineral density; LIHC cis rs7618501 0.602 rs2240327 chr3:50113034 C/T cg21467203 chr3:49911342 NA -0.42 -7.51 -0.38 5.13e-13 Intelligence (multi-trait analysis); LIHC cis rs798554 0.679 rs7784066 chr7:2819727 T/A cg04166393 chr7:2884313 GNA12 0.41 5.81 0.3 1.43e-8 Height; LIHC cis rs7072216 0.763 rs2147900 chr10:100174721 T/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.33 -0.32 7.67e-10 Metabolite levels; LIHC cis rs6547741 1.000 rs1919126 chr2:27801418 C/A cg27432699 chr2:27873401 GPN1 0.72 11.74 0.54 5.55e-27 Oral cavity cancer; LIHC cis rs16828019 0.852 rs12759050 chr1:41664204 T/A cg03387723 chr1:41708464 SCMH1 -0.44 -7.13 -0.36 6.14e-12 Intelligence (multi-trait analysis); LIHC trans rs8073060 0.544 rs9912939 chr17:34005264 T/G cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9649465 1.000 rs2109725 chr7:123325459 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.02e-15 Migraine; LIHC cis rs921968 0.643 rs2556386 chr2:219534530 C/T cg18887096 chr2:219472410 PLCD4 -0.38 -6.41 -0.33 4.95e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1144333 1.000 rs78223982 chr1:76465203 T/C cg22875332 chr1:76189707 ACADM 0.4 6.15 0.32 2.16e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7511006 0.893 rs5771104 chr22:50651839 C/T cg16473166 chr22:50639996 SELO 0.58 8.95 0.44 2.34e-17 Obesity-related traits; LIHC cis rs2153535 0.580 rs915351 chr6:8442793 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs7845219 0.544 rs4735332 chr8:95923660 C/T cg16049864 chr8:95962084 TP53INP1 -0.46 -6.91 -0.35 2.43e-11 Type 2 diabetes; LIHC cis rs7412746 0.658 rs12410394 chr1:150860186 G/A cg15448220 chr1:150897856 SETDB1 0.41 6.39 0.33 5.42e-10 Melanoma; LIHC cis rs12478296 1.000 rs56162244 chr2:243018690 A/G cg18898632 chr2:242989856 NA -0.46 -6.3 -0.32 9.04e-10 Obesity-related traits; LIHC trans rs2243480 1.000 rs6964530 chr7:65718851 G/C cg10756647 chr7:56101905 PSPH -1.03 -12.48 -0.56 1.05e-29 Diabetic kidney disease; LIHC trans rs9929218 0.953 rs3118235 chr16:68732977 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.61 8.89 0.43 3.5e-17 Colorectal cancer; LIHC trans rs61931739 0.534 rs11053072 chr12:34202399 A/C cg26384229 chr12:38710491 ALG10B 0.55 7.06 0.36 9.12e-12 Morning vs. evening chronotype; LIHC cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg14004847 chr7:1930337 MAD1L1 -0.42 -6.17 -0.32 1.95e-9 Bipolar disorder and schizophrenia; LIHC cis rs10489202 0.608 rs6659593 chr1:168072152 A/T cg24449463 chr1:168025552 DCAF6 -0.55 -8.35 -0.41 1.66e-15 Schizophrenia; LIHC cis rs7586673 0.857 rs16845580 chr2:161920884 T/C cg22496339 chr2:162101262 NA 0.66 10.1 0.48 3.58e-21 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.534 rs9366078 chr6:167399512 A/G cg23791538 chr6:167370224 RNASET2 0.74 13.96 0.6 2.27e-35 Crohn's disease; LIHC cis rs79149102 0.579 rs79916508 chr15:75373721 A/C cg16226627 chr15:75307476 SCAMP5 0.49 8.62 0.42 2.57e-16 Lung cancer; LIHC trans rs61931739 0.500 rs7309931 chr12:34483471 A/C cg26384229 chr12:38710491 ALG10B 0.63 8.13 0.4 8.07e-15 Morning vs. evening chronotype; LIHC trans rs759244 0.676 rs1005416 chr4:25060151 G/C cg18314424 chr4:184718605 NA 0.32 6.14 0.32 2.32e-9 Interleukin-2 receptor antagonist levels; LIHC cis rs7927771 0.832 rs10838698 chr11:47385923 G/A cg20307385 chr11:47447363 PSMC3 0.44 5.82 0.3 1.35e-8 Subjective well-being; LIHC cis rs10078 0.528 rs2434697 chr5:466811 T/C cg24955955 chr5:415729 AHRR 0.59 11.21 0.52 4.69e-25 Fat distribution (HIV); LIHC cis rs13191362 0.935 rs7763118 chr6:162954720 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.68 5.89 0.3 9.11e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs36051895 0.530 rs4142064 chr9:5221818 C/T cg02405213 chr9:5042618 JAK2 -0.59 -9.14 -0.44 5.66e-18 Pediatric autoimmune diseases; LIHC cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg23758822 chr17:41437982 NA 0.92 17.05 0.68 1.3e-47 Menopause (age at onset); LIHC cis rs904251 0.523 rs2797794 chr6:37480604 T/C cg01843034 chr6:37503916 NA -0.48 -8.21 -0.41 4.45e-15 Cognitive performance; LIHC cis rs61041384 0.661 rs74240770 chr12:123691742 T/G cg00376283 chr12:123451042 ABCB9 -0.54 -5.9 -0.3 8.66e-9 Schizophrenia; LIHC cis rs2153535 0.580 rs2225766 chr6:8481833 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs7116495 0.737 rs2460252 chr11:71567504 T/C cg26138937 chr11:71823887 C11orf51 0.69 6.64 0.34 1.23e-10 Severe influenza A (H1N1) infection; LIHC cis rs1670533 0.818 rs6835141 chr4:1070140 G/T cg27284194 chr4:1044797 NA 0.6 8.92 0.43 2.94e-17 Recombination rate (females); LIHC cis rs939574 0.660 rs6716253 chr2:220127016 G/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.94 6.39 0.33 5.43e-10 Platelet distribution width; LIHC trans rs859980 0.514 rs9386402 chr6:104519786 C/T cg15957524 chr2:233415782 TIGD1;EIF4E2 0.46 6.54 0.33 2.19e-10 Tourette's syndrome or obsessive-compulsive disorder; LIHC cis rs79149102 1.000 rs78940327 chr15:75152480 G/A cg16226627 chr15:75307476 SCAMP5 0.44 5.93 0.31 7.41e-9 Lung cancer; LIHC cis rs9303401 0.659 rs62081314 chr17:56778328 A/G cg25039879 chr17:56429692 SUPT4H1 0.77 8.57 0.42 3.73e-16 Cognitive test performance; LIHC cis rs12926788 0.689 rs34365165 chr16:24856208 G/A cg00339695 chr16:24857497 SLC5A11 0.59 8.15 0.4 6.79e-15 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06258179 chr7:92463261 CDK6 -0.46 -6.32 -0.32 8.06e-10 Pancreatic cancer; LIHC cis rs853679 0.517 rs9393890 chr6:28063855 C/T cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg20887711 chr4:1340912 KIAA1530 -0.7 -10.49 -0.49 1.67e-22 Obesity-related traits; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05926266 chr13:39612065 C13orf23;NHLRC3 0.42 6.04 0.31 4.02e-9 Hepatitis; LIHC cis rs7208859 0.623 rs216423 chr17:28942109 G/C cg14067834 chr17:29058358 SUZ12P 0.62 6.45 0.33 3.84e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.88 0.3 9.88e-9 Electroencephalogram traits; LIHC cis rs2842992 0.789 rs3818300 chr6:160201677 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.68 12.22 0.55 9.59e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs17685 0.753 rs10233282 chr7:75790081 C/T cg04592579 chr7:75616294 TMEM120A 0.41 7.01 0.35 1.28e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs8113308 0.810 rs16983256 chr19:52449481 G/A cg14959425 chr7:20447707 ITGB8 -0.47 -6.11 -0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs422249 0.547 rs174535 chr11:61551356 T/C cg27386326 chr11:61587980 NA 0.7 15.04 0.63 1.32e-39 Trans fatty acid levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17128461 chr4:186125334 KIAA1430 0.44 6.29 0.32 9.98e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10489202 1.000 rs17556487 chr1:167889094 T/A cg24449463 chr1:168025552 DCAF6 -0.52 -6.28 -0.32 1.05e-9 Schizophrenia; LIHC cis rs2425143 1.000 rs2425078 chr20:34298163 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.49 -5.76 -0.3 1.85e-8 Blood protein levels; LIHC cis rs9457247 1.000 rs448060 chr6:167382622 A/G cg23791538 chr6:167370224 RNASET2 -0.67 -11.63 -0.53 1.44e-26 Crohn's disease; LIHC cis rs965469 0.901 rs7270135 chr20:3247922 T/C cg25506879 chr20:3388711 C20orf194 -0.58 -6.76 -0.34 5.89e-11 IFN-related cytopenia; LIHC cis rs10870270 0.956 rs4131689 chr10:133744328 A/C cg08754478 chr10:133766260 PPP2R2D 0.53 7.94 0.39 2.93e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1799949 0.931 rs9912203 chr17:41445145 A/G cg23758822 chr17:41437982 NA -0.94 -17.6 -0.69 7.7e-50 Menopause (age at onset); LIHC cis rs7129220 0.588 rs7931957 chr11:10094304 G/A cg01453529 chr11:10209919 SBF2 -0.39 -6.91 -0.35 2.43e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12445461 chr9:6681608 NA 0.46 7.1 0.36 7.39e-12 Cognitive function; LIHC cis rs9467773 1.000 rs9467791 chr6:26562486 A/G cg12292205 chr6:26970375 C6orf41 -0.34 -5.89 -0.3 9.06e-9 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.931 rs7099593 chr10:35366878 A/C cg04310649 chr10:35416472 CREM -0.42 -5.78 -0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7017697 1.000 rs2410612 chr8:19681647 A/G cg17834443 chr8:19674713 INTS10 0.42 6.57 0.33 1.88e-10 Breast cancer; LIHC cis rs7395581 0.798 rs10769252 chr11:47343955 A/G cg26139080 chr11:47293733 MADD -0.5 -8.33 -0.41 2.01e-15 HDL cholesterol; LIHC cis rs2841277 0.708 rs10083490 chr14:105402418 A/G cg15352829 chr14:105391018 PLD4 0.41 8.96 0.44 2.08e-17 Rheumatoid arthritis; LIHC cis rs1949733 0.523 rs55977448 chr4:8542918 G/T cg11789530 chr4:8429930 ACOX3 -0.59 -8.17 -0.4 6.22e-15 Response to antineoplastic agents; LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg05484376 chr2:27715224 FNDC4 0.37 6.28 0.32 1.03e-9 Total body bone mineral density; LIHC cis rs11673344 0.832 rs76781063 chr19:37526942 T/C cg27390819 chr19:37464633 NA -0.51 -6.16 -0.32 2.02e-9 Obesity-related traits; LIHC cis rs700651 0.821 rs700690 chr2:198727626 A/G cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Intracranial aneurysm; LIHC trans rs800082 1.000 rs1405599 chr3:144328759 T/C cg24215973 chr2:240111563 HDAC4 -0.5 -7.44 -0.37 8.47e-13 Smoking behavior; LIHC cis rs10089 1.000 rs72794396 chr5:127501386 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.41 0.33 4.9e-10 Ileal carcinoids; LIHC cis rs1864585 0.806 rs17778223 chr8:10729692 A/T cg11557530 chr8:9911760 MSRA -0.5 -6.03 -0.31 4.18e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs4332037 0.722 rs55934553 chr7:1914059 T/C cg23043544 chr7:2124092 MAD1L1 -0.43 -6.51 -0.33 2.6e-10 Bipolar disorder; LIHC cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg03517284 chr6:25882590 NA -0.66 -8.74 -0.43 1.05e-16 Intelligence (multi-trait analysis); LIHC cis rs7216064 0.953 rs2086744 chr17:65849275 C/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs10056811 0.538 rs2035191 chr5:74413713 T/C cg02573091 chr5:74908125 NA 0.52 6.47 0.33 3.31e-10 Coronary artery disease; LIHC cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg00750074 chr16:89608354 SPG7 -0.38 -5.76 -0.3 1.89e-8 Multiple myeloma (IgH translocation); LIHC trans rs1814175 0.817 rs1390676 chr11:50056778 C/T cg03929089 chr4:120376271 NA -0.88 -18.26 -0.7 1.79e-52 Height; LIHC cis rs6754311 0.731 rs2236783 chr2:136594158 G/A cg17750252 chr2:136567154 LCT 0.32 5.88 0.3 9.69e-9 Mosquito bite size; LIHC cis rs7829975 0.714 rs11784052 chr8:8671962 C/T cg06636001 chr8:8085503 FLJ10661 0.37 6.06 0.31 3.53e-9 Mood instability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23249942 chr5:109027037 MAN2A1 0.44 6.83 0.35 3.98e-11 Pancreatic cancer; LIHC cis rs225245 0.755 rs7217565 chr17:34024707 C/A cg05299278 chr17:33885742 SLFN14 0.23 6.2 0.32 1.65e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg25072359 chr17:41440525 NA 0.38 6.11 0.31 2.65e-9 Menopause (age at onset); LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg07424592 chr7:64974309 NA -0.45 -6.88 -0.35 2.8e-11 Calcium levels; LIHC cis rs875971 0.862 rs1612452 chr7:65573896 T/A cg18876405 chr7:65276391 NA -0.39 -6.85 -0.35 3.53e-11 Aortic root size; LIHC cis rs9303401 0.646 rs9892425 chr17:57241938 C/T cg12560992 chr17:57184187 TRIM37 0.44 6.29 0.32 9.63e-10 Cognitive test performance; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg06873352 chr17:61820015 STRADA 0.74 12.66 0.56 2.2e-30 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.06e-10 Alzheimer's disease; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg00829961 chr8:25909326 NA -0.45 -6.14 -0.32 2.33e-9 Preeclampsia; LIHC cis rs11148252 0.532 rs9526975 chr13:53255804 C/T cg00495681 chr13:53174319 NA 0.73 13.31 0.58 7.69e-33 Lewy body disease; LIHC cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.22e-8 Menopause (age at onset); LIHC cis rs10464366 0.510 rs62442212 chr7:39146896 A/C cg18850127 chr7:39170497 POU6F2 0.41 7.31 0.37 1.93e-12 IgG glycosylation; LIHC cis rs716804 0.765 rs4366477 chr11:10306881 A/G cg01453529 chr11:10209919 SBF2 -0.29 -5.87 -0.3 1.01e-8 Neuroticism; LIHC cis rs9309473 0.687 rs6710659 chr2:73607510 A/G cg20560298 chr2:73613845 ALMS1 -0.48 -7.45 -0.37 7.63e-13 Metabolite levels; LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg17178900 chr1:205818956 PM20D1 0.65 9.69 0.46 8.92e-20 Menarche (age at onset); LIHC cis rs9326248 0.581 rs10892076 chr11:116988936 G/A cg11861562 chr11:117069780 TAGLN 0.41 6.76 0.34 5.86e-11 Blood protein levels; LIHC cis rs12602486 1.000 rs59592125 chr17:42279265 A/G cg08193365 chr17:42277699 NA 1.0 6.8 0.34 4.75e-11 Glycated hemoglobin levels; LIHC trans rs8002861 0.967 rs9533691 chr13:44482208 A/G cg17145862 chr1:211918768 LPGAT1 0.67 13.23 0.58 1.48e-32 Leprosy; LIHC cis rs1005277 0.579 rs1740745 chr10:38520056 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7572733 0.534 rs770657 chr2:198674184 C/A cg03934865 chr2:198174659 NA 0.46 6.58 0.34 1.74e-10 Dermatomyositis; LIHC cis rs9814567 1.000 rs7427492 chr3:134261654 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8081395 0.836 rs2063353 chr17:57889192 T/G cg13753209 chr17:57696993 CLTC -0.48 -7.37 -0.37 1.3e-12 White blood cell count; LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg00280220 chr17:61926910 NA -0.42 -6.82 -0.35 4.03e-11 Prudent dietary pattern; LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg02951883 chr7:2050386 MAD1L1 -0.73 -12.56 -0.56 4.99e-30 Bipolar disorder and schizophrenia; LIHC cis rs8017423 0.935 rs716122 chr14:90792313 A/C cg14092571 chr14:90743983 NA 0.44 6.93 0.35 2.16e-11 Mortality in heart failure; LIHC cis rs965469 1.000 rs6139064 chr20:3277050 G/T cg25506879 chr20:3388711 C20orf194 -0.55 -6.74 -0.34 6.9e-11 IFN-related cytopenia; LIHC cis rs754466 0.914 rs12219971 chr10:79701526 T/C cg17075019 chr10:79541650 NA -0.58 -7.55 -0.38 4.12e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17152411 0.947 rs17152408 chr10:126649007 C/T cg07906193 chr10:126599966 NA 0.43 7.25 0.37 2.74e-12 Height; LIHC cis rs1707322 0.721 rs4564187 chr1:46166861 G/C cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9911578 1.000 rs9807057 chr17:56889952 A/C cg12560992 chr17:57184187 TRIM37 0.97 17.46 0.69 2.94e-49 Intelligence (multi-trait analysis); LIHC cis rs9399135 0.838 rs4896126 chr6:135342786 C/A cg24558204 chr6:135376177 HBS1L 0.42 6.86 0.35 3.16e-11 Red blood cell count; LIHC cis rs10493773 0.775 rs11161649 chr1:86165446 A/C cg17807903 chr1:86174739 ZNHIT6 -0.56 -10.22 -0.48 1.46e-21 Urate levels in overweight individuals; LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.85 -0.35 3.51e-11 Diastolic blood pressure; LIHC cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg12311346 chr5:56204834 C5orf35 -0.58 -7.62 -0.38 2.48e-13 Initial pursuit acceleration; LIHC cis rs10876993 0.928 rs2640636 chr12:58077544 A/G cg15848620 chr12:58087721 OS9 -0.59 -8.1 -0.4 9.68e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs9394841 0.692 rs9394834 chr6:41806793 G/A cg08135965 chr6:41755394 TOMM6 0.46 6.13 0.31 2.41e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs11718455 0.960 rs35666538 chr3:44004826 A/G cg08738300 chr3:44038990 NA 0.51 8.94 0.44 2.43e-17 Coronary artery disease; LIHC trans rs1624005 1.000 rs1756329 chr14:43379366 C/A cg11960719 chr5:1510684 LPCAT1 -0.35 -6.21 -0.32 1.54e-9 Methotrexate-induced interstitial lung disease in rheumatoid arthritis; LIHC cis rs9326248 0.911 rs11216284 chr11:117003060 C/T cg26566898 chr11:117069891 TAGLN 0.48 7.61 0.38 2.68e-13 Blood protein levels; LIHC trans rs6598955 0.671 rs6686100 chr1:26617338 G/C cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.21 -0.41 4.62e-15 Obesity-related traits; LIHC cis rs7131987 0.903 rs11050153 chr12:29405148 T/C cg05697976 chr12:29376483 FAR2 0.33 6.86 0.35 3.29e-11 QT interval; LIHC cis rs6964587 1.000 rs2299238 chr7:91654517 G/A cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg06634786 chr22:41940651 POLR3H -0.82 -9.02 -0.44 1.4e-17 Vitiligo; LIHC cis rs7903847 0.620 rs7923385 chr10:99117097 T/A cg06359132 chr10:99160096 RRP12 -0.39 -5.98 -0.31 5.5e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs9733 0.596 rs6690725 chr1:150632322 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs600806 0.815 rs10745356 chr1:109960270 C/A cg16275483 chr1:110013120 SYPL2 -0.47 -5.86 -0.3 1.09e-8 Intelligence (multi-trait analysis); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg14941975 chr14:105892536 MTA1 0.41 6.23 0.32 1.34e-9 Alopecia areata; LIHC cis rs9399135 0.967 rs12527707 chr6:135324511 G/A cg22676075 chr6:135203613 NA 0.38 6.17 0.32 1.88e-9 Red blood cell count; LIHC cis rs9916302 0.904 rs55689507 chr17:37404436 G/C cg00129232 chr17:37814104 STARD3 -0.4 -6.5 -0.33 2.92e-10 Glomerular filtration rate (creatinine); LIHC cis rs8058578 0.775 rs8046391 chr16:30836648 G/C cg00531865 chr16:30841666 NA -0.4 -6.07 -0.31 3.48e-9 Multiple myeloma; LIHC cis rs9549367 0.774 rs9549696 chr13:113875062 C/T cg00898013 chr13:113819073 PROZ -0.41 -6.91 -0.35 2.39e-11 Platelet distribution width; LIHC cis rs722599 0.748 rs7145173 chr14:75351647 G/A cg11812906 chr14:75593930 NEK9 -0.45 -7.22 -0.36 3.36e-12 IgG glycosylation; LIHC cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg12311636 chr6:118886798 C6orf204 -0.55 -6.29 -0.32 9.78e-10 Diastolic blood pressure; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg04525508 chr3:124774877 HEG1 -0.45 -6.14 -0.32 2.3e-9 Alopecia areata; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09260951 chr22:39096513 JOSD1 -0.39 -6.04 -0.31 4.07e-9 Pancreatic cancer; LIHC cis rs35146811 0.555 rs2527896 chr7:99537653 A/G cg19636519 chr7:99541626 NA 0.31 6.01 0.31 4.67e-9 Coronary artery disease; LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.7 -0.34 8.47e-11 Lymphocyte counts; LIHC cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg21724239 chr8:58056113 NA 0.55 7.45 0.37 7.63e-13 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg02290350 chr8:58132656 NA 0.48 8.74 0.43 1.04e-16 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.542 rs5770725 chr22:50256309 C/T cg02269571 chr22:50332266 NA 0.7 8.05 0.4 1.38e-14 Schizophrenia; LIHC cis rs7617773 0.817 rs3731555 chr3:48206102 G/A cg11946769 chr3:48343235 NME6 0.88 11.05 0.51 1.82e-24 Coronary artery disease; LIHC cis rs2120019 1.000 rs34655806 chr15:75362586 T/C cg09165964 chr15:75287851 SCAMP5 -0.59 -9.25 -0.45 2.48e-18 Blood trace element (Zn levels); LIHC cis rs9399135 0.967 rs6902438 chr6:135336587 C/T cg22676075 chr6:135203613 NA 0.4 6.51 0.33 2.73e-10 Red blood cell count; LIHC trans rs1814175 0.586 rs10769603 chr11:49688837 T/C cg03929089 chr4:120376271 NA -0.81 -14.81 -0.63 1.05e-38 Height; LIHC trans rs801193 1.000 rs7789184 chr7:66210195 A/T cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.89e-11 Aortic root size; LIHC cis rs4953318 0.619 rs10198247 chr2:46362677 C/T cg12428440 chr2:46370979 PRKCE -0.45 -6.19 -0.32 1.69e-9 Red blood cell count;Hematocrit;Red blood cell traits; LIHC cis rs4925386 0.808 rs1741634 chr20:60925979 A/C cg03945807 chr20:60948434 NA -0.36 -6.62 -0.34 1.37e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs4631830 0.747 rs745180 chr10:51504493 A/C cg20129853 chr10:51489980 NA 0.4 8.66 0.42 1.87e-16 Prostate-specific antigen levels; LIHC cis rs787274 1.000 rs1891403 chr9:115527183 C/T cg13803584 chr9:115635662 SNX30 -0.56 -6.27 -0.32 1.11e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10779751 1.000 rs1064261 chr1:11288758 C/T cg08854313 chr1:11322531 MTOR 0.79 11.09 0.51 1.25e-24 Body mass index; LIHC cis rs1691799 0.867 rs1168309 chr12:66726439 A/G cg16791601 chr12:66731901 HELB 0.58 14.33 0.61 8.13e-37 White blood cell count (basophil); LIHC cis rs428668 0.523 rs3926389 chr5:150677806 C/T cg11125805 chr5:150678162 SLC36A3 0.53 12.28 0.55 5.55e-29 Skin aging (microtopography measurement); LIHC cis rs11955398 0.716 rs1870014 chr5:60000470 T/C cg02684056 chr5:59996105 DEPDC1B 0.4 5.89 0.3 9.26e-9 Intelligence (multi-trait analysis); LIHC cis rs4665809 1.000 rs4233709 chr2:26291493 C/T cg04944784 chr2:26401820 FAM59B 0.63 7.87 0.39 4.71e-14 Gut microbiome composition (summer); LIHC cis rs6430585 0.528 rs309161 chr2:136688749 A/G cg07169764 chr2:136633963 MCM6 -0.94 -14.23 -0.61 1.97e-36 Corneal structure; LIHC cis rs6938 0.575 rs12902515 chr15:75160998 G/C cg14664628 chr15:75095509 CSK -0.51 -7.31 -0.37 1.88e-12 Breast cancer; LIHC cis rs965469 1.000 rs6051736 chr20:3296898 T/C cg25506879 chr20:3388711 C20orf194 -0.57 -6.83 -0.35 3.86e-11 IFN-related cytopenia; LIHC cis rs1023500 0.596 rs133350 chr22:42429049 A/G cg04733989 chr22:42467013 NAGA 0.67 9.4 0.45 8.26e-19 Schizophrenia; LIHC cis rs17685 0.753 rs1637039 chr7:75693009 C/T cg16684958 chr7:75615977 POR 0.51 8.61 0.42 2.78e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10078 1.000 rs10078 chr5:438102 G/T cg24955955 chr5:415729 AHRR 0.5 9.51 0.46 3.38e-19 Fat distribution (HIV); LIHC cis rs875971 0.508 rs6947808 chr7:66045082 A/G cg18876405 chr7:65276391 NA -0.41 -7.37 -0.37 1.27e-12 Aortic root size; LIHC cis rs4969178 0.641 rs4969141 chr17:76391653 C/T cg02836325 chr17:76403955 PGS1 0.34 6.67 0.34 1.04e-10 HDL cholesterol levels; LIHC cis rs6665290 0.904 rs1045286 chr1:227179037 A/C cg10327440 chr1:227177885 CDC42BPA 1.15 30.51 0.86 1.26e-99 Myeloid white cell count; LIHC cis rs7945718 0.967 rs7930077 chr11:12778769 C/T cg25843174 chr11:12811716 TEAD1 0.34 7.67 0.38 1.83e-13 Educational attainment (years of education); LIHC cis rs672413 0.620 rs663646 chr5:78285778 G/A cg26802063 chr5:78281964 ARSB -0.39 -6.31 -0.32 8.74e-10 Blood and toenail selenium levels;Blood protein levels; LIHC cis rs10857712 0.754 rs7921041 chr10:135229239 G/C cg19904058 chr10:135279010 LOC619207 -0.35 -5.77 -0.3 1.77e-8 Systemic lupus erythematosus; LIHC trans rs1005277 0.579 rs2472176 chr10:38382921 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg24846343 chr22:24311635 DDTL 0.67 13.37 0.59 4.22e-33 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs919433 0.714 rs2333855 chr2:198200213 T/G cg03934865 chr2:198174659 NA -0.54 -8.48 -0.42 7.04e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17539620 0.624 rs62432737 chr6:154834772 G/A cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs2504916 0.830 rs2504934 chr6:160781666 A/G cg18126027 chr6:160773436 SLC22A3 0.38 5.76 0.3 1.87e-8 Response to hepatitis C treatment; LIHC cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1669338 0.510 rs3804788 chr3:3169466 C/A cg16797762 chr3:3221439 CRBN -0.98 -8.3 -0.41 2.4e-15 White matter integrity; LIHC cis rs3741404 1.000 rs11603042 chr11:64003843 G/T cg24431193 chr11:63883947 FLRT1;MACROD1 -0.41 -6.09 -0.31 3.11e-9 Platelet count; LIHC cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg06238570 chr21:40685208 BRWD1 0.58 6.86 0.35 3.21e-11 Cognitive function; LIHC trans rs801193 0.805 rs12532355 chr7:66070584 C/G cg26939375 chr7:64535504 NA -0.43 -7.33 -0.37 1.64e-12 Aortic root size; LIHC cis rs2576037 0.526 rs538221 chr18:44375111 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.21 -0.36 3.71e-12 Personality dimensions; LIHC cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg04944784 chr2:26401820 FAM59B -0.71 -9.3 -0.45 1.7e-18 Gut microbiome composition (summer); LIHC cis rs9649213 0.593 rs3801264 chr7:97950620 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.52e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs3768617 0.510 rs6424889 chr1:183091796 G/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs344364 0.511 rs2906912 chr16:1953151 G/A cg26897989 chr16:1907736 C16orf73 -0.47 -5.89 -0.3 9.03e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs763121 0.853 rs2076028 chr22:39150450 G/A cg06022373 chr22:39101656 GTPBP1 0.67 12.02 0.55 5.26e-28 Menopause (age at onset); LIHC trans rs1814175 0.618 rs1851843 chr11:50021846 T/C cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs16828019 0.852 rs35190461 chr1:41543135 T/C cg20697417 chr1:41786797 NA 0.31 5.86 0.3 1.09e-8 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.790 rs6060542 chr20:34249061 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -11.29 -0.52 2.38e-25 Total cholesterol levels; LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg22907277 chr7:1156413 C7orf50 0.52 8.07 0.4 1.19e-14 Longevity;Endometriosis; LIHC cis rs7715806 0.500 rs3797581 chr5:75002895 G/T cg00601450 chr5:74908170 NA 0.49 6.24 0.32 1.31e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6831352 0.760 rs1311616 chr4:100012303 T/G cg12011299 chr4:100065546 ADH4 0.65 10.73 0.5 2.43e-23 Alcohol dependence; LIHC cis rs10870270 0.957 rs10870307 chr10:133780610 T/C cg26149184 chr10:133730230 NA 0.47 7.4 0.37 1.07e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2050392 0.829 rs306589 chr10:30723831 A/G cg25182066 chr10:30743637 MAP3K8 -0.49 -7.98 -0.4 2.19e-14 Inflammatory bowel disease; LIHC cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg18357526 chr6:26021779 HIST1H4A 0.94 12.82 0.57 5.48e-31 Intelligence (multi-trait analysis); LIHC cis rs4927850 0.709 rs6765762 chr3:195652851 G/A cg01181863 chr3:195395398 SDHAP2 -0.83 -8.77 -0.43 8.65e-17 Pancreatic cancer; LIHC cis rs6076065 0.748 rs4815198 chr20:23343491 T/C cg11657817 chr20:23433608 CST11 0.32 6.8 0.34 4.79e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs2066819 0.786 rs116934693 chr12:56696545 T/G cg26714650 chr12:56694279 CS -1.42 -13.82 -0.6 8e-35 Psoriasis vulgaris; LIHC cis rs10504229 0.610 rs7840469 chr8:58146992 C/T cg21448741 chr8:58168803 NA 0.3 5.74 0.3 2.04e-8 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05397629 chr11:3848986 RHOG 0.4 6.21 0.32 1.51e-9 Pancreatic cancer; LIHC cis rs752092 1.000 rs8033360 chr15:101778710 C/A cg25114630 chr15:101792522 CHSY1 0.56 7.12 0.36 6.56e-12 Corneal structure; LIHC cis rs7100689 0.753 rs1856773 chr10:82060484 T/A cg00277334 chr10:82204260 NA -0.55 -6.91 -0.35 2.43e-11 Post bronchodilator FEV1; LIHC cis rs5769765 0.954 rs5770739 chr22:50268014 C/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs1707322 0.752 rs10789467 chr1:46118745 C/G cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2839627 0.561 rs6586250 chr21:44270229 C/T cg03543861 chr21:44258195 NA 0.53 8.63 0.42 2.32e-16 Information processing speed; LIHC cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.48e-11 Gut microbiome composition (summer); LIHC cis rs875971 0.800 rs427557 chr7:65519250 A/G cg18876405 chr7:65276391 NA 0.41 7.35 0.37 1.43e-12 Aortic root size; LIHC cis rs826838 0.967 rs34496261 chr12:39023829 G/A cg26384229 chr12:38710491 ALG10B 0.9 12.01 0.54 5.87e-28 Heart rate; LIHC cis rs7619427 0.507 rs7616472 chr3:44016039 G/A cg24966902 chr3:44043705 NA 0.46 6.99 0.35 1.46e-11 Schizophrenia; LIHC cis rs7131987 0.617 rs3764953 chr12:29502236 T/C cg05697976 chr12:29376483 FAR2 0.29 5.79 0.3 1.58e-8 QT interval; LIHC cis rs2439831 0.850 rs60883262 chr15:44076503 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.51 0.42 5.59e-16 Lung cancer in ever smokers; LIHC cis rs2439831 0.867 rs2245176 chr15:43750762 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.96 0.44 2.2e-17 Lung cancer in ever smokers; LIHC cis rs7666738 0.962 rs4699605 chr4:99064379 A/G cg05340658 chr4:99064831 C4orf37 0.68 11.53 0.53 3.39e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg00656387 chr3:40428638 ENTPD3 0.48 7.94 0.39 2.97e-14 Renal cell carcinoma; LIHC cis rs7677751 0.806 rs1800812 chr4:55094629 G/T cg17187183 chr4:55093834 PDGFRA 0.68 8.53 0.42 4.89e-16 Corneal astigmatism; LIHC cis rs11785400 1.000 rs3735994 chr8:143742683 C/T cg24634471 chr8:143751801 JRK 0.51 8.23 0.41 4.08e-15 Schizophrenia; LIHC cis rs9649213 0.593 rs6975156 chr7:97925534 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.76 -0.3 1.86e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs877282 0.583 rs7072970 chr10:822757 G/A cg22713356 chr15:30763199 NA 0.85 7.21 0.36 3.56e-12 Uric acid levels; LIHC cis rs9549328 0.800 rs9549619 chr13:113632620 C/G cg08528486 chr13:113648767 MCF2L -0.39 -6.38 -0.33 5.82e-10 Systolic blood pressure; LIHC cis rs10751667 1.000 rs10751667 chr11:941941 A/T cg06064525 chr11:970664 AP2A2 -0.47 -11.7 -0.53 8.17e-27 Alzheimer's disease (late onset); LIHC cis rs1401999 0.966 rs4148585 chr3:183670642 A/G cg05044414 chr3:183734942 ABCC5 0.35 6.07 0.31 3.4e-9 Anterior chamber depth; LIHC cis rs9322817 0.607 rs7772567 chr6:105155782 C/A cg02098413 chr6:105308735 HACE1 -0.41 -7.76 -0.39 1e-13 Thyroid stimulating hormone; LIHC cis rs7534824 0.625 rs12569251 chr1:101372040 C/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.64 6.52 0.33 2.57e-10 Refractive astigmatism; LIHC cis rs727505 1.000 rs9655845 chr7:124513355 G/C cg23710748 chr7:124431027 NA -0.33 -5.93 -0.31 7.54e-9 Lewy body disease; LIHC cis rs10193935 0.748 rs12467253 chr2:42697588 A/C cg27598129 chr2:42591480 NA 0.7 8.93 0.43 2.7e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs1190552 0.846 rs3783381 chr14:102965435 A/G cg10241871 chr14:102965420 TECPR2 -0.48 -7.53 -0.38 4.65e-13 Blood protein levels; LIHC cis rs9549367 0.826 rs9549713 chr13:113905308 G/T cg18105134 chr13:113819100 PROZ -0.68 -11.64 -0.53 1.29e-26 Platelet distribution width; LIHC cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg08499158 chr17:42289980 UBTF -0.49 -7.95 -0.39 2.74e-14 Total body bone mineral density; LIHC cis rs7666738 0.830 rs34916200 chr4:98851593 C/T cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs28374715 0.635 rs28557159 chr15:41657353 T/C cg18705301 chr15:41695430 NDUFAF1 -1.01 -14.97 -0.63 2.57e-39 Ulcerative colitis; LIHC cis rs35110281 0.720 rs162372 chr21:44928863 C/T cg21573476 chr21:45109991 RRP1B 0.59 10.79 0.5 1.54e-23 Mean corpuscular volume; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Menopause (age at onset); LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg03874509 chr1:107600012 PRMT6 0.75 12.0 0.54 6.56e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg24209194 chr3:40518798 ZNF619 0.56 8.16 0.4 6.31e-15 Renal cell carcinoma; LIHC trans rs9531686 0.935 rs9547000 chr13:85549213 C/G cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.25 0.32 1.19e-9 Anorexia nervosa; LIHC cis rs311392 0.554 rs2666884 chr8:55100906 T/C cg11783602 chr8:55087084 NA -0.3 -6.02 -0.31 4.55e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs17102423 0.896 rs8004805 chr14:65579720 T/C cg11161011 chr14:65562177 MAX -0.5 -7.0 -0.35 1.33e-11 Obesity-related traits; LIHC cis rs10847980 0.590 rs79798267 chr12:123321819 A/T cg25930673 chr12:123319894 HIP1R 1.03 11.42 0.53 8.16e-26 Adiponectin levels; LIHC cis rs921968 0.643 rs611203 chr2:219472325 G/A cg17980119 chr2:219472607 PLCD4 0.33 5.72 0.3 2.3e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs8103278 1.000 rs35302007 chr19:46219145 G/C cg02376097 chr19:46275166 DMPK -0.48 -7.5 -0.38 5.4e-13 Coronary artery disease; LIHC cis rs3741404 0.620 rs12787945 chr11:63977546 G/A cg18225595 chr11:63971243 STIP1 0.64 10.54 0.5 1.14e-22 Platelet count; LIHC trans rs11098499 0.780 rs12504773 chr4:120562149 G/C cg25214090 chr10:38739885 LOC399744 0.56 8.71 0.43 1.28e-16 Corneal astigmatism; LIHC cis rs7523273 0.565 rs2761422 chr1:207893266 A/T cg22525895 chr1:207977042 MIR29B2 0.44 7.09 0.36 7.68e-12 Schizophrenia; LIHC cis rs2412488 1.000 rs6834934 chr4:54242085 T/C cg22241045 chr4:54363911 LNX1 -0.46 -7.29 -0.37 2.2e-12 DNA methylation (variation); LIHC cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg10546459 chr2:36825355 FEZ2 0.51 6.31 0.32 8.89e-10 Height; LIHC cis rs1670533 1.000 rs11724371 chr4:1052125 T/C cg18657303 chr4:1051139 NA 0.36 5.73 0.3 2.26e-8 Recombination rate (females); LIHC cis rs1005277 0.579 rs2474571 chr10:38384639 T/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs1005277 0.579 rs1740747 chr10:38520465 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8180040 0.967 rs4858856 chr3:47565424 G/A cg27129171 chr3:47204927 SETD2 0.54 8.63 0.42 2.32e-16 Colorectal cancer; LIHC cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg06108461 chr20:60628389 TAF4 0.61 7.91 0.39 3.67e-14 Obesity-related traits; LIHC cis rs7246657 0.943 rs13345116 chr19:37847098 A/T cg23950597 chr19:37808831 NA -0.44 -5.97 -0.31 5.93e-9 Coronary artery calcification; LIHC cis rs2073300 0.826 rs6048809 chr20:23443788 C/T cg12062639 chr20:23401060 NAPB 0.85 10.21 0.48 1.55e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2730245 1.000 rs2730241 chr7:158723014 T/C cg24397884 chr7:158709396 WDR60 -0.45 -6.85 -0.35 3.4e-11 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25979624 chr1:54954752 NA 0.4 6.28 0.32 1e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs17253792 0.822 rs77990307 chr14:56070049 T/C cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs882732 1.000 rs10139629 chr14:95035277 C/T cg14866387 chr14:95027382 SERPINA4 -0.45 -6.48 -0.33 3.14e-10 Blood protein levels; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg02990361 chr1:107599529 PRMT6 0.64 10.65 0.5 4.71e-23 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs7246657 0.943 rs10404602 chr19:37825633 A/T cg10208301 chr11:6592745 DNHD1 0.47 6.27 0.32 1.11e-9 Coronary artery calcification; LIHC cis rs11971779 0.555 rs6950143 chr7:139054418 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -9.98 -0.47 9.38e-21 Platelet count; LIHC cis rs10489202 1.000 rs34192847 chr1:168064317 A/T cg24449463 chr1:168025552 DCAF6 -0.5 -6.35 -0.32 6.85e-10 Schizophrenia; LIHC cis rs4713118 0.869 rs7773070 chr6:27728827 T/C cg20933634 chr6:27740509 NA 0.46 6.15 0.32 2.22e-9 Parkinson's disease; LIHC cis rs6831352 0.879 rs29001208 chr4:100052539 A/C cg12011299 chr4:100065546 ADH4 -0.62 -10.52 -0.49 1.28e-22 Alcohol dependence; LIHC cis rs67478160 0.529 rs12880413 chr14:104267407 A/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.86 0.57 3.97e-31 Schizophrenia; LIHC cis rs735860 0.737 rs2115564 chr6:53173482 C/A cg10236188 chr6:53219634 NA -0.4 -7.08 -0.36 8.03e-12 Glaucoma; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00570391 chr7:815417 HEATR2 0.43 6.37 0.33 5.99e-10 Longevity; LIHC cis rs3736485 0.934 rs28410165 chr15:51875019 C/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs459571 0.959 rs455381 chr9:136905577 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.57 -8.76 -0.43 9.14e-17 Platelet distribution width; LIHC cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.46 -7.97 -0.4 2.32e-14 Height; LIHC cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.24 0.41 3.66e-15 Platelet count; LIHC cis rs10752881 1.000 rs4593781 chr1:182984983 C/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs12824058 0.798 rs4759652 chr12:130808771 C/T cg26677194 chr12:130822605 PIWIL1 0.52 7.22 0.36 3.47e-12 Menopause (age at onset); LIHC cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg24549020 chr5:56110836 MAP3K1 0.55 7.03 0.36 1.16e-11 Initial pursuit acceleration; LIHC trans rs12310956 0.532 rs11052922 chr12:33957476 A/G cg26384229 chr12:38710491 ALG10B 0.44 6.18 0.32 1.82e-9 Morning vs. evening chronotype; LIHC cis rs7208859 0.673 rs9914271 chr17:29232625 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1461503 0.966 rs7944630 chr11:122838844 G/A cg14473756 chr11:122847823 NA -0.37 -6.67 -0.34 1.02e-10 Menarche (age at onset); LIHC cis rs9399135 0.967 rs4896120 chr6:135293512 C/G cg22676075 chr6:135203613 NA 0.38 6.25 0.32 1.25e-9 Red blood cell count; LIHC cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg23205692 chr1:25664452 TMEM50A 0.39 6.3 0.32 8.96e-10 Plateletcrit;Mean corpuscular volume; LIHC cis rs9658691 0.607 rs9658757 chr10:90769455 T/C cg03111039 chr10:90751583 FAS;ACTA2 -0.84 -6.24 -0.32 1.29e-9 Mosquito bite size; LIHC cis rs898097 0.578 rs9906163 chr17:80908174 T/C cg15664640 chr17:80829946 TBCD 0.45 7.4 0.37 1.04e-12 Breast cancer; LIHC cis rs11122272 0.766 rs2486732 chr1:231531476 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -11.33 -0.52 1.69e-25 Hemoglobin concentration; LIHC cis rs17376456 0.877 rs10064520 chr5:93427358 T/C cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs11608355 0.515 rs12826754 chr12:109923244 A/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs1552244 0.882 rs7636817 chr3:10014876 G/T cg13047869 chr3:10149882 C3orf24 0.43 5.92 0.3 7.79e-9 Alzheimer's disease; LIHC cis rs7712401 0.755 rs3213794 chr5:122161638 A/C cg18764291 chr5:122110994 SNX2 0.35 5.98 0.31 5.77e-9 Mean platelet volume; LIHC cis rs17384381 1.000 rs12758237 chr1:85870783 G/A cg16011679 chr1:85725395 C1orf52 0.82 8.66 0.42 1.86e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg18404041 chr3:52824283 ITIH1 -0.55 -8.97 -0.44 2.04e-17 Bipolar disorder; LIHC cis rs2115630 0.653 rs61394864 chr15:85170174 T/C cg12501888 chr15:85177176 SCAND2 -0.49 -7.57 -0.38 3.4e-13 P wave terminal force; LIHC cis rs1475911 0.507 rs11702347 chr21:43526454 C/T cg19766460 chr21:43528205 UMODL1;C21orf128 1.32 20.54 0.74 1.16e-61 IgG glycosylation; LIHC cis rs875971 0.660 rs801192 chr7:66031952 C/G cg00343986 chr7:65444356 GUSB -0.4 -5.99 -0.31 5.42e-9 Aortic root size; LIHC cis rs6459788 0.527 rs6980250 chr7:157228710 C/T cg17306686 chr7:157230923 NA 0.43 9.51 0.46 3.6e-19 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC trans rs9951602 0.512 rs1599633 chr18:76643526 T/C cg02800362 chr5:177631904 HNRNPAB 0.64 10.24 0.48 1.24e-21 Obesity-related traits; LIHC cis rs7412746 0.611 rs10888394 chr1:150749913 C/T cg18016565 chr1:150552671 MCL1 0.54 10.13 0.48 2.88e-21 Melanoma; LIHC cis rs1862618 0.671 rs906631 chr5:56245803 C/G cg24531977 chr5:56204891 C5orf35 0.52 7.47 0.37 6.66e-13 Initial pursuit acceleration; LIHC cis rs2991971 0.901 rs11211122 chr1:45954650 C/T cg05343316 chr1:45956843 TESK2 -0.44 -6.53 -0.33 2.35e-10 High light scatter reticulocyte count; LIHC cis rs1797081 0.840 rs10904820 chr10:16848473 A/G cg23933602 chr10:16859644 RSU1 1.0 19.76 0.73 1.6e-58 Platelet distribution width; LIHC cis rs2836950 0.527 rs2836958 chr21:40623526 T/C cg06238570 chr21:40685208 BRWD1 -0.46 -7.47 -0.37 6.73e-13 Menarche (age at onset); LIHC cis rs12134245 0.747 rs11164912 chr1:92005191 A/T cg07090678 chr1:91966139 CDC7 0.5 6.76 0.34 5.81e-11 Breast cancer; LIHC cis rs8017423 1.000 rs769044 chr14:90671138 A/G cg04374321 chr14:90722782 PSMC1 0.72 13.7 0.6 2.35e-34 Mortality in heart failure; LIHC cis rs4919087 0.892 rs10882880 chr10:99008068 G/A cg25902810 chr10:99078978 FRAT1 0.62 8.95 0.44 2.29e-17 Monocyte count; LIHC trans rs10213084 1.000 rs10213045 chr4:147500975 T/C cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs8177179 0.967 rs4287912 chr3:133437778 A/G cg16262614 chr3:133464971 TF 0.45 10.18 0.48 1.97e-21 Iron status biomarkers (transferrin levels); LIHC cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.94 9.37 0.45 1.04e-18 Platelet count; LIHC trans rs7613875 0.620 rs7430334 chr3:50078221 T/C cg21659725 chr3:3221576 CRBN -0.55 -8.16 -0.4 6.51e-15 Body mass index; LIHC cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.2 -0.45 3.69e-18 Bipolar disorder; LIHC cis rs1664789 0.715 rs697111 chr5:53261330 G/A ch.5.1024479R chr5:53302184 ARL15 0.44 6.59 0.34 1.71e-10 Waist circumference adjusted for body mass index; LIHC cis rs4700695 0.719 rs27079 chr5:65443966 C/T cg21114390 chr5:65439923 SFRS12 -0.58 -8.38 -0.41 1.37e-15 Facial morphology (factor 19); LIHC cis rs7937890 1.000 rs6486190 chr11:14401216 A/C cg02886208 chr11:14281011 SPON1 -0.57 -8.46 -0.42 8.07e-16 Mitochondrial DNA levels; LIHC cis rs10751667 0.600 rs14346 chr11:1011829 T/C cg06064525 chr11:970664 AP2A2 -0.44 -10.73 -0.5 2.49e-23 Alzheimer's disease (late onset); LIHC cis rs1005277 0.540 rs2145487 chr10:38010077 A/G cg25427524 chr10:38739819 LOC399744 -0.63 -12.14 -0.55 1.97e-28 Extrinsic epigenetic age acceleration; LIHC cis rs12478296 0.901 rs67951957 chr2:243004901 A/G cg06360820 chr2:242988706 NA -0.82 -12.26 -0.55 6.88e-29 Obesity-related traits; LIHC cis rs6701037 0.681 rs34370567 chr1:175131340 C/T cg00321850 chr1:175162397 KIAA0040 -0.41 -6.7 -0.34 8.8e-11 Alcohol dependence; LIHC cis rs116095464 0.558 rs55776650 chr5:273826 G/A cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs1577917 1.000 rs2324843 chr6:86617501 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.29 -0.37 2.21e-12 Response to antipsychotic treatment; LIHC cis rs7100689 0.598 rs2342815 chr10:82086532 T/C cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs3849570 0.695 rs62265411 chr3:81573660 T/C cg07356753 chr3:81810745 GBE1 -0.53 -8.03 -0.4 1.6e-14 Waist circumference;Body mass index; LIHC cis rs1577917 0.958 rs6454488 chr6:86450842 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.88 -0.3 9.5e-9 Response to antipsychotic treatment; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg06873352 chr17:61820015 STRADA 0.72 12.23 0.55 9.15e-29 Prudent dietary pattern; LIHC cis rs1580019 0.510 rs4723162 chr7:32543804 C/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 26.03 0.82 4.07e-83 Cognitive ability; LIHC cis rs3793683 0.965 rs3829131 chr10:134564627 A/G cg27297192 chr10:134578999 INPP5A -0.51 -7.88 -0.39 4.29e-14 Migraine; LIHC cis rs7818688 0.697 rs2904889 chr8:95940598 T/G cg16049864 chr8:95962084 TP53INP1 0.54 6.1 0.31 2.95e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2439831 0.557 rs13329084 chr15:44151063 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.58 -6.66 -0.34 1.07e-10 Lung cancer in ever smokers; LIHC cis rs8027181 1.000 rs4777542 chr15:73082366 C/T cg25996835 chr15:72978165 BBS4;HIGD2B -0.5 -7.54 -0.38 4.16e-13 Triglyceride levels; LIHC cis rs35306767 0.855 rs11253468 chr10:903261 G/A cg20503657 chr10:835505 NA 1.07 12.12 0.55 2.31e-28 Eosinophil percentage of granulocytes; LIHC cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.08 0.31 3.13e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs73198271 0.563 rs3748143 chr8:8655237 A/G cg01851573 chr8:8652454 MFHAS1 -0.52 -6.02 -0.31 4.48e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs13108904 0.846 rs4045131 chr4:1228797 A/G cg00684032 chr4:1343700 KIAA1530 0.46 6.75 0.34 6.52e-11 Obesity-related traits; LIHC cis rs55665837 0.540 rs7938266 chr11:14709324 A/G cg25251204 chr11:14927456 NA 0.41 5.86 0.3 1.06e-8 Vitamin D levels; LIHC cis rs10197940 0.578 rs2444264 chr2:152310928 G/T cg19508488 chr2:152266495 RIF1 -0.46 -6.48 -0.33 3.25e-10 Lung cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03052632 chr12:57634626 NDUFA4L2 0.44 7.51 0.38 5.19e-13 Pancreatic cancer; LIHC trans rs4714291 0.802 rs3008833 chr6:39986303 G/A cg02267698 chr19:7991119 CTXN1 -0.38 -6.46 -0.33 3.66e-10 Strep throat; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.48 -5.98 -0.31 5.47e-9 Diastolic blood pressure; LIHC cis rs13343954 0.825 rs2216595 chr19:33533292 C/T cg27124370 chr19:33622961 WDR88 0.42 5.73 0.3 2.18e-8 Colorectal cancer; LIHC cis rs3020736 0.500 rs7292241 chr22:42492063 G/A cg05082376 chr22:42548792 NA 0.39 5.71 0.3 2.41e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.757 rs1183085 chr7:2875570 G/A cg19346786 chr7:2764209 NA -0.42 -5.98 -0.31 5.72e-9 Height; LIHC cis rs780096 0.587 rs10205219 chr2:27568565 T/C cg22903471 chr2:27725779 GCKR -0.49 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs9341808 0.559 rs7762895 chr6:81061431 C/T cg08355045 chr6:80787529 NA 0.34 6.86 0.35 3.22e-11 Sitting height ratio; LIHC cis rs4910157 1 rs4910157 chr11:8941215 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.38 6.31 0.32 8.75e-10 Tonsillectomy; LIHC cis rs710216 0.536 rs710222 chr1:43413653 A/G cg03128534 chr1:43423976 SLC2A1 0.61 9.76 0.47 5.11e-20 Red cell distribution width; LIHC cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg23205692 chr1:25664452 TMEM50A 0.4 6.54 0.33 2.18e-10 Erythrocyte sedimentation rate; LIHC cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg21448741 chr8:58168803 NA 0.33 5.86 0.3 1.11e-8 Developmental language disorder (linguistic errors); LIHC cis rs9783347 1.000 rs4150641 chr11:18370739 C/A cg15585147 chr11:18324498 HPS5 0.42 6.7 0.34 8.6e-11 Pancreatic cancer; LIHC cis rs4605213 0.686 rs9896627 chr17:49328705 A/G cg00965052 chr17:49230932 NME1;NME1-NME2 -0.44 -5.81 -0.3 1.41e-8 Height; LIHC cis rs3820068 0.581 rs6666373 chr1:15939884 A/T cg17385448 chr1:15911702 AGMAT 0.35 6.11 0.31 2.64e-9 Systolic blood pressure; LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg14671364 chr1:107599128 PRMT6 0.53 7.93 0.39 3.05e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg20818283 chr2:191399100 TMEM194B 0.46 6.19 0.32 1.75e-9 Pulse pressure; LIHC cis rs17401966 0.931 rs3748579 chr1:10420937 C/T cg19773385 chr1:10388646 KIF1B -0.39 -6.75 -0.34 6.16e-11 Hepatocellular carcinoma; LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.88 0.57 3.12e-31 Prudent dietary pattern; LIHC cis rs4555082 0.874 rs56263609 chr14:105756944 C/T cg06808227 chr14:105710500 BRF1 -0.48 -5.9 -0.3 8.64e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs739401 0.595 rs6578305 chr11:3001120 C/T cg25174290 chr11:3078921 CARS 0.58 8.88 0.43 3.97e-17 Longevity; LIHC cis rs875971 0.545 rs2460427 chr7:65619205 T/C cg11764359 chr7:65958608 NA -0.51 -6.96 -0.35 1.76e-11 Aortic root size; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 9.32e-15 Prudent dietary pattern; LIHC cis rs1577917 0.837 rs806529 chr6:86467121 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.32 -5.74 -0.3 2.09e-8 Response to antipsychotic treatment; LIHC cis rs881375 0.631 rs10739577 chr9:123668854 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.4 0.33 5.18e-10 Rheumatoid arthritis; LIHC cis rs4759375 1.000 rs10773006 chr12:123790051 T/C cg00376283 chr12:123451042 ABCB9 -0.5 -6.4 -0.33 5.02e-10 HDL cholesterol; LIHC cis rs1387259 0.929 rs2956703 chr12:48670294 C/T cg21466736 chr12:48725269 NA -0.71 -10.96 -0.51 3.57e-24 Obstructive sleep apnea trait (apnea hypopnea index); LIHC trans rs875971 0.660 rs10263935 chr7:66096028 A/G cg26939375 chr7:64535504 NA 0.4 6.41 0.33 4.92e-10 Aortic root size; LIHC cis rs11048434 0.736 rs1805733 chr12:9089272 A/C cg04155231 chr12:9217510 LOC144571 0.31 6.02 0.31 4.58e-9 Sjögren's syndrome; LIHC cis rs11690935 1.000 rs312918 chr2:172569587 C/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -19.31 -0.72 1.02e-56 Schizophrenia; LIHC cis rs34779708 0.931 rs11596502 chr10:35387187 A/C cg03585969 chr10:35415529 CREM 0.88 13.23 0.58 1.56e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6429082 0.509 rs2803845 chr1:235520228 C/G cg26050004 chr1:235667680 B3GALNT2 0.43 6.38 0.33 5.76e-10 Adiposity; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20237291 chr3:113233670 CCDC52 0.4 6.59 0.34 1.66e-10 Calcium levels; LIHC cis rs941873 0.803 rs2105461 chr10:81101679 A/G cg09469691 chr10:81107165 PPIF -0.67 -10.39 -0.49 3.72e-22 Height; LIHC cis rs1190552 0.841 rs56144019 chr14:102949731 G/A cg10241871 chr14:102965420 TECPR2 -0.49 -7.74 -0.39 1.11e-13 Blood protein levels; LIHC cis rs2737618 0.722 rs2737676 chr1:200086839 T/C cg21825944 chr1:200113062 NR5A2 -0.41 -6.59 -0.34 1.62e-10 Uric acid levels; LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg10755058 chr3:40428713 ENTPD3 0.42 7.14 0.36 5.82e-12 Renal cell carcinoma; LIHC cis rs34779708 0.897 rs9665538 chr10:35461038 T/C cg04310649 chr10:35416472 CREM -0.42 -5.77 -0.3 1.76e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3790844 0.876 rs3790847 chr1:200006217 G/T cg13229857 chr1:200006247 NR5A2 0.43 7.03 0.36 1.16e-11 Pancreatic cancer; LIHC cis rs611744 0.503 rs13282220 chr8:109263043 T/C cg21045802 chr8:109455806 TTC35 0.55 9.37 0.45 9.95e-19 Dupuytren's disease; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg06329022 chr17:26926511 SPAG5 0.38 6.13 0.31 2.35e-9 Morning vs. evening chronotype; LIHC cis rs1008375 1.000 rs1006722 chr4:17618713 A/G cg02297831 chr4:17616191 MED28 -0.45 -7.18 -0.36 4.51e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4423214 0.840 rs1790344 chr11:71176897 A/G cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC cis rs11190604 0.832 rs2489041 chr10:102333635 G/C cg07080220 chr10:102295463 HIF1AN 0.57 7.23 0.36 3.09e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs12477438 0.765 rs6542846 chr2:99563654 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.1 -0.4 9.71e-15 Chronic sinus infection; LIHC cis rs769267 0.896 rs7253807 chr19:19631444 A/T cg03709012 chr19:19516395 GATAD2A 1.0 16.23 0.66 2.48e-44 Tonsillectomy; LIHC cis rs16828019 0.929 rs10524 chr1:41726473 T/C cg03962019 chr1:41807865 NA 0.49 7.12 0.36 6.54e-12 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20720553 chr15:101792477 CHSY1 0.48 6.35 0.32 6.76e-10 Lung function (FEV1/FVC); LIHC cis rs2224391 0.822 rs36055504 chr6:5262230 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -5.96 -0.31 6.36e-9 Height; LIHC cis rs9322817 0.691 rs9391244 chr6:105257690 G/A cg02098413 chr6:105308735 HACE1 -0.43 -8.06 -0.4 1.28e-14 Thyroid stimulating hormone; LIHC cis rs2576037 0.583 rs4890698 chr18:44489725 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.71 11.13 0.52 9.42e-25 Personality dimensions; LIHC cis rs796364 0.806 rs11684942 chr2:201009136 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs7772486 0.790 rs2243665 chr6:146208120 A/C cg23711669 chr6:146136114 FBXO30 0.63 10.31 0.49 7.24e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.659 rs34913878 chr17:56897094 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.32 0.58 6.47e-33 Cognitive test performance; LIHC cis rs4862750 0.914 rs11943333 chr4:187872455 A/G cg03452623 chr4:187889614 NA -0.3 -7.9 -0.39 3.91e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs425277 0.916 rs414777 chr1:2101687 G/A cg24578937 chr1:2090814 PRKCZ 0.5 8.93 0.43 2.73e-17 Height; LIHC cis rs1005277 0.579 rs2472175 chr10:38382901 T/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs892961 0.836 rs8071497 chr17:75414358 T/C cg01320579 chr17:75405842 SEPT9 0.52 7.44 0.37 8.37e-13 Airflow obstruction; LIHC cis rs4319547 0.915 rs7316734 chr12:123117425 A/G cg23029597 chr12:123009494 RSRC2 -0.49 -6.87 -0.35 3.03e-11 Body mass index; LIHC cis rs3784262 1.000 rs12907038 chr15:58244032 C/G cg12031962 chr15:58353849 ALDH1A2 -0.31 -6.05 -0.31 3.85e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7614311 0.636 rs73117041 chr3:63896266 A/T cg22134162 chr3:63841271 THOC7 -0.53 -6.02 -0.31 4.53e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg02290350 chr8:58132656 NA 0.4 8.38 0.41 1.4e-15 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09299307 chr5:86709023 CCNH 0.45 6.28 0.32 1.01e-9 Pancreatic cancer; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg10150615 chr22:24372951 LOC391322 -0.57 -8.19 -0.4 5.42e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8180040 0.652 rs13077398 chr3:47011120 G/C cg02527881 chr3:46936655 PTH1R -0.35 -7.16 -0.36 5.02e-12 Colorectal cancer; LIHC trans rs6952808 0.595 rs3800917 chr7:2167939 A/G cg04565464 chr8:145669602 NFKBIL2 -0.37 -6.04 -0.31 4.08e-9 Bipolar disorder and schizophrenia; LIHC cis rs7523273 0.586 rs2761425 chr1:207894033 C/T cg22525895 chr1:207977042 MIR29B2 -0.52 -8.0 -0.4 1.97e-14 Schizophrenia; LIHC cis rs2569991 0.636 rs9211 chr3:12939546 A/G cg22481960 chr3:13008800 IQSEC1 0.44 7.84 0.39 5.63e-14 Periodontitis (DPAL); LIHC cis rs9308433 0.529 rs6660335 chr1:214501855 C/T cg06198575 chr1:214491504 SMYD2 0.54 5.93 0.31 7.59e-9 IgG glycosylation; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg03721293 chr16:90014378 DEF8 0.39 6.62 0.34 1.38e-10 Skin colour saturation; LIHC cis rs9399135 0.967 rs4896122 chr6:135295081 T/C cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.36e-11 Red blood cell count; LIHC cis rs17106184 1.000 rs72904713 chr1:51312992 A/G cg07174182 chr1:51127561 FAF1 -0.62 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC cis rs597539 0.652 rs627731 chr11:68698663 A/C cg04772025 chr11:68637568 NA 0.5 6.4 0.33 5.12e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7607369 0.791 rs12468043 chr2:219354197 C/A cg02985541 chr2:219472218 PLCD4 0.43 6.95 0.35 1.84e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC trans rs3942852 0.568 rs10769314 chr11:48097620 C/T cg03929089 chr4:120376271 NA -0.46 -6.06 -0.31 3.57e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs6429082 0.509 rs7516807 chr1:235523555 G/T cg26050004 chr1:235667680 B3GALNT2 0.42 6.38 0.33 5.72e-10 Adiposity; LIHC cis rs2153535 0.580 rs6941670 chr6:8446346 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.98 0.4 2.19e-14 Motion sickness; LIHC cis rs9911578 0.933 rs2632508 chr17:56533235 G/A cg12560992 chr17:57184187 TRIM37 0.95 16.84 0.67 9.18e-47 Intelligence (multi-trait analysis); LIHC cis rs9381040 0.610 rs9357345 chr6:41025118 G/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.02 -0.31 4.41e-9 Alzheimer's disease (late onset); LIHC cis rs2439831 0.850 rs12441861 chr15:44060883 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.62 0.34 1.4e-10 Lung cancer in ever smokers; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg03885098 chr1:207991780 LOC148696 0.5 6.15 0.32 2.21e-9 Hip circumference; LIHC cis rs6450176 0.625 rs3776725 chr5:53290138 C/A ch.5.1024479R chr5:53302184 ARL15 -0.89 -16.49 -0.67 2.23e-45 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs3008870 1.000 rs2985818 chr1:67398916 G/A cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC cis rs7582180 0.700 rs4640404 chr2:100980523 C/T cg14675211 chr2:100938903 LONRF2 -0.51 -7.54 -0.38 4.27e-13 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.672 rs10501398 chr11:68331715 C/G cg01657329 chr11:68192670 LRP5 0.51 7.56 0.38 3.65e-13 Total body bone mineral density; LIHC cis rs1506636 0.886 rs6466878 chr7:123272278 T/C cg03229431 chr7:123269106 ASB15 -0.6 -12.35 -0.56 3.1e-29 Plateletcrit;Platelet count; LIHC cis rs10078 0.848 rs890985 chr5:479746 C/G cg08916839 chr5:415575 AHRR 0.47 9.87 0.47 2.21e-20 Fat distribution (HIV); LIHC cis rs2760061 0.626 rs672977 chr1:228120288 A/C cg02753203 chr1:228287806 NA -0.49 -7.87 -0.39 4.68e-14 Diastolic blood pressure; LIHC trans rs1814175 0.645 rs7115592 chr11:50013243 A/G cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs116095464 0.558 rs6555055 chr5:226160 A/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs6430585 0.583 rs3087343 chr2:136622543 T/G cg25344623 chr2:136566232 LCT -0.36 -5.74 -0.3 2.03e-8 Corneal structure; LIHC cis rs3008870 1.000 rs12132068 chr1:67451924 G/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.38 -0.66 6.33e-45 Lymphocyte percentage of white cells; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg22903471 chr2:27725779 GCKR -0.5 -8.81 -0.43 6.51e-17 Total body bone mineral density; LIHC cis rs10871290 0.801 rs3851726 chr16:74471644 G/C cg01733217 chr16:74700730 RFWD3 -0.42 -7.23 -0.36 3.2e-12 Breast cancer; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg13495025 chr9:130230056 LRSAM1 0.49 6.07 0.31 3.34e-9 Lung function (FEV1); LIHC cis rs12220238 0.915 rs11000948 chr10:76031721 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.61 -6.03 -0.31 4.3e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg09359103 chr1:154839909 KCNN3 -0.29 -5.74 -0.3 2.11e-8 Prostate cancer; LIHC cis rs1728785 0.818 rs11648503 chr16:68598938 G/A cg02972257 chr16:68554789 NA -0.57 -6.49 -0.33 2.99e-10 Ulcerative colitis; LIHC cis rs7833986 0.534 rs2667980 chr8:56896541 A/T cg23139584 chr8:56987506 RPS20;SNORD54 0.87 8.76 0.43 9.08e-17 Height; LIHC cis rs1552244 0.882 rs17050672 chr3:10025463 G/A cg08888203 chr3:10149979 C3orf24 0.51 6.26 0.32 1.17e-9 Alzheimer's disease; LIHC cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg01518246 chr11:63870912 FLRT1;MACROD1 0.51 7.49 0.38 5.97e-13 Mean platelet volume; LIHC cis rs796364 0.755 rs203762 chr2:200905136 C/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs9733 0.596 rs72702552 chr1:150677462 G/A cg17724175 chr1:150552817 MCL1 0.48 9.74 0.47 6.17e-20 Tonsillectomy; LIHC cis rs17685 0.672 rs56343450 chr7:75796235 C/T cg04610667 chr7:75704037 NA -0.35 -6.21 -0.32 1.54e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2933343 0.729 rs1680794 chr3:128620390 A/G cg25356066 chr3:128598488 ACAD9 0.53 7.47 0.37 6.71e-13 IgG glycosylation; LIHC cis rs9614461 0.702 rs2294202 chr22:45738327 A/T cg13318129 chr22:45737514 FAM118A 0.49 6.51 0.33 2.75e-10 Tonsillectomy; LIHC trans rs2243480 1.000 rs709607 chr7:65449541 C/G cg10756647 chr7:56101905 PSPH -1.05 -12.59 -0.56 3.99e-30 Diabetic kidney disease; LIHC cis rs4713118 0.513 rs149950 chr6:28033039 T/G cg16479474 chr6:28041457 NA 0.38 6.32 0.32 8.32e-10 Parkinson's disease; LIHC cis rs916888 0.773 rs199447 chr17:44812188 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.87 0.35 2.95e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7715806 0.500 rs17563589 chr5:74980019 A/G cg19683494 chr5:74908142 NA 0.69 7.91 0.39 3.57e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9916302 0.784 rs34473775 chr17:37396201 G/T cg03013999 chr17:37608204 MED1 0.34 5.77 0.3 1.78e-8 Glomerular filtration rate (creatinine); LIHC trans rs6489882 0.703 rs10850095 chr12:113360575 T/C cg10175203 chr3:128143634 NA 0.39 6.22 0.32 1.47e-9 Chronic lymphocytic leukemia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21284376 chr1:72748601 NEGR1 -0.37 -6.08 -0.31 3.22e-9 Pancreatic cancer; LIHC cis rs7412746 0.588 rs10305664 chr1:150839686 A/C cg18016565 chr1:150552671 MCL1 0.56 10.24 0.48 1.19e-21 Melanoma; LIHC cis rs6486730 1.000 rs6486730 chr12:129275027 C/T cg09035930 chr12:129282057 SLC15A4 0.39 6.9 0.35 2.56e-11 Systemic lupus erythematosus; LIHC cis rs7100689 0.646 rs7894762 chr10:82086779 C/G cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs8180040 1.000 rs811115 chr3:47322133 C/T cg02527881 chr3:46936655 PTH1R -0.3 -5.89 -0.3 9.21e-9 Colorectal cancer; LIHC cis rs7927771 0.542 rs7108479 chr11:47781460 G/T cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs921968 0.541 rs687747 chr2:219399627 T/C cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs72781680 0.611 rs7596060 chr2:24334361 A/G cg06627628 chr2:24431161 ITSN2 0.66 7.77 0.39 9.34e-14 Lymphocyte counts; LIHC cis rs10911363 0.573 rs2702181 chr1:183516985 T/A cg09173681 chr1:183549694 NCF2 0.56 9.79 0.47 4.16e-20 Systemic lupus erythematosus; LIHC cis rs2976388 0.578 rs13263987 chr8:143827387 A/C cg24634471 chr8:143751801 JRK -0.44 -6.05 -0.31 3.74e-9 Urinary tract infection frequency; LIHC cis rs265548 0.646 rs36692 chr19:17906839 C/T cg16744531 chr19:17905626 B3GNT3 0.59 8.9 0.43 3.3e-17 Tumor biomarkers; LIHC cis rs11148252 0.574 rs9536247 chr13:53279542 T/C cg02158880 chr13:53174818 NA 0.37 5.81 0.3 1.47e-8 Lewy body disease; LIHC cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg18230493 chr5:56204884 C5orf35 -0.44 -6.07 -0.31 3.3e-9 Initial pursuit acceleration; LIHC cis rs8141529 0.632 rs5762803 chr22:29193638 G/C cg15103426 chr22:29168792 CCDC117 0.66 10.54 0.5 1.11e-22 Lymphocyte counts; LIHC cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC trans rs7615952 0.688 rs17334074 chr3:125540460 A/G cg07211511 chr3:129823064 LOC729375 0.48 7.7 0.38 1.44e-13 Blood pressure (smoking interaction); LIHC cis rs6088580 0.634 rs4911423 chr20:32999386 T/A cg08999081 chr20:33150536 PIGU -0.67 -13.34 -0.58 5.73e-33 Glomerular filtration rate (creatinine); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01505148 chr19:56170617 U2AF2 0.45 6.76 0.34 6.15e-11 Longevity; LIHC cis rs12477438 0.765 rs1115757 chr2:99660146 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs4908768 0.520 rs11121216 chr1:8738944 A/G cg20416874 chr1:8611966 RERE -0.6 -11.79 -0.54 3.85e-27 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs116095464 0.558 rs62347683 chr5:230331 C/T cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs12477438 1.000 rs12466388 chr2:99916538 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -7.65 -0.38 2.05e-13 Chronic sinus infection; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg01696603 chr6:125623444 HDDC2 0.4 6.07 0.31 3.48e-9 Bilirubin levels; LIHC cis rs7927771 1.000 rs2290850 chr11:47807774 T/C cg20135002 chr11:47629003 NA -0.54 -9.17 -0.44 4.61e-18 Subjective well-being; LIHC cis rs67311347 0.605 rs1880762 chr3:40283215 A/G cg00656387 chr3:40428638 ENTPD3 0.43 6.9 0.35 2.59e-11 Renal cell carcinoma; LIHC cis rs1499614 1.000 rs2707832 chr7:66136549 C/T cg18252515 chr7:66147081 NA -1.28 -18.54 -0.71 1.29e-53 Gout; LIHC trans rs4650994 1.000 rs10798619 chr1:178532517 A/G cg05059571 chr16:84539110 KIAA1609 -0.37 -6.12 -0.31 2.56e-9 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1215050 0.740 rs783936 chr4:98928628 G/T cg05340658 chr4:99064831 C4orf37 -0.42 -6.45 -0.33 3.76e-10 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.54 -9.85 -0.47 2.49e-20 Total body bone mineral density; LIHC cis rs7116495 0.609 rs4944243 chr11:71674354 T/C cg26138937 chr11:71823887 C11orf51 -1.31 -10.34 -0.49 5.49e-22 Severe influenza A (H1N1) infection; LIHC cis rs8017423 0.669 rs7153190 chr14:90703904 T/G cg14092571 chr14:90743983 NA -0.38 -6.1 -0.31 2.89e-9 Mortality in heart failure; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.0 -0.31 5.01e-9 Diastolic blood pressure; LIHC cis rs2236918 0.710 rs2526700 chr1:242019999 C/A cg17736920 chr1:242011382 EXO1 0.43 6.27 0.32 1.06e-9 Menopause (age at onset); LIHC cis rs2412488 0.927 rs10001201 chr4:54269096 G/A cg22241045 chr4:54363911 LNX1 -0.41 -6.71 -0.34 8.15e-11 DNA methylation (variation); LIHC cis rs6089829 0.889 rs6122348 chr20:61663921 C/T cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs6502050 0.835 rs6502067 chr17:80111205 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs600806 0.850 rs4970752 chr1:109930852 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs3770081 1.000 rs3770090 chr2:86263288 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -9.3 -0.45 1.76e-18 Facial emotion recognition (sad faces); LIHC cis rs7633770 0.664 rs34000414 chr3:46689958 G/A cg11219411 chr3:46661640 NA -0.35 -5.79 -0.3 1.56e-8 Coronary artery disease; LIHC cis rs7208859 0.673 rs11649765 chr17:29233888 T/A cg14067834 chr17:29058358 SUZ12P 0.67 6.54 0.33 2.2e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4969178 0.896 rs12602206 chr17:76397133 A/G cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs10861342 1.000 rs7968711 chr12:105447921 G/A cg23923672 chr12:105501055 KIAA1033 0.68 7.87 0.39 4.7e-14 IgG glycosylation; LIHC cis rs7572733 0.515 rs700675 chr2:198700216 G/A cg03934865 chr2:198174659 NA 0.45 6.49 0.33 2.93e-10 Dermatomyositis; LIHC cis rs787274 1.000 rs2796037 chr9:115511826 C/T cg13803584 chr9:115635662 SNX30 0.52 6.14 0.32 2.25e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -6.99 -0.35 1.41e-11 Diabetic kidney disease; LIHC cis rs11122272 0.766 rs2024879 chr1:231528638 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg14780466 chr2:20870812 GDF7 -0.42 -8.58 -0.42 3.43e-16 Abdominal aortic aneurysm; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25116269 chr2:55509523 PRDXDD1P -0.48 -6.92 -0.35 2.2e-11 Cognitive function; LIHC cis rs208520 0.955 rs208532 chr6:66961280 T/A cg07460842 chr6:66804631 NA -0.65 -7.0 -0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs10504229 0.593 rs11781042 chr8:57993056 A/T cg02290350 chr8:58132656 NA 0.32 6.93 0.35 2.1e-11 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.541 rs2263163 chr10:38389887 G/A cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs748404 0.697 rs492743 chr15:43560945 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.39 0.41 1.28e-15 Lung cancer; LIHC cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg21448741 chr8:58168803 NA 0.35 5.76 0.3 1.88e-8 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.817 rs7483795 chr11:49704930 G/A cg18944383 chr4:111397179 ENPEP 0.26 6.67 0.34 1.05e-10 Height; LIHC cis rs9420 0.961 rs12146541 chr11:57508678 G/C cg19752551 chr11:57585705 CTNND1 -0.53 -7.41 -0.37 9.81e-13 Schizophrenia; LIHC cis rs7100689 0.577 rs10749551 chr10:82054001 A/C cg01528321 chr10:82214614 TSPAN14 0.88 11.96 0.54 8.49e-28 Post bronchodilator FEV1; LIHC trans rs6600671 0.966 rs6600664 chr1:121222436 G/A cg09829573 chr1:144692074 NBPF9 -0.39 -6.94 -0.35 1.92e-11 Hip geometry; LIHC cis rs34172651 0.517 rs35560136 chr16:24788915 T/A cg00339695 chr16:24857497 SLC5A11 0.69 10.02 0.48 6.78e-21 Intelligence (multi-trait analysis); LIHC cis rs1580019 0.844 rs1376290 chr7:32486922 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.94 15.79 0.65 1.38e-42 Cognitive ability; LIHC cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg11764359 chr7:65958608 NA -0.68 -9.26 -0.45 2.34e-18 Aortic root size; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg02993280 chr1:107599747 PRMT6 -0.69 -11.17 -0.52 6.48e-25 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs1814175 0.645 rs10839456 chr11:49964093 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.83 0.35 3.93e-11 Height; LIHC cis rs703842 0.642 rs73123375 chr12:58063664 C/T cg18357645 chr12:58087776 OS9 -0.5 -7.52 -0.38 4.97e-13 Multiple sclerosis; LIHC cis rs7961581 0.957 rs1353361 chr12:71608199 C/A cg05756094 chr12:71608604 NA 0.37 5.86 0.3 1.08e-8 Type 2 diabetes; LIHC cis rs2153535 0.580 rs1414350 chr6:8472331 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs6570726 0.902 rs406979 chr6:145838983 G/T cg23711669 chr6:146136114 FBXO30 0.56 10.32 0.49 6.24e-22 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23307218 chr19:11616766 ECSIT;ZNF653 -0.47 -6.73 -0.34 7.36e-11 Pancreatic cancer; LIHC cis rs919433 0.926 rs787996 chr2:198216805 A/G cg03934865 chr2:198174659 NA 0.53 8.31 0.41 2.21e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9399135 0.933 rs41294852 chr6:135376379 T/G cg22676075 chr6:135203613 NA 0.41 6.62 0.34 1.36e-10 Red blood cell count; LIHC cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.39 0.37 1.15e-12 Obesity-related traits; LIHC cis rs644799 1.000 rs623191 chr11:95548359 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.52e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9948 0.529 rs62152773 chr2:97448073 T/C cg01990225 chr2:97406019 LMAN2L -0.73 -6.31 -0.32 8.85e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs870825 1.000 rs870823 chr4:185588195 G/A cg04058563 chr4:185651563 MLF1IP 0.78 6.28 0.32 1.02e-9 Blood protein levels; LIHC cis rs7027203 0.790 rs10123836 chr9:96584109 G/T cg14396892 chr9:96623032 NA -0.31 -6.14 -0.32 2.23e-9 DNA methylation (variation); LIHC cis rs2242116 0.796 rs9852082 chr3:46972377 T/C cg27129171 chr3:47204927 SETD2 0.57 9.12 0.44 6.69e-18 Birth weight; LIHC cis rs2204008 0.660 rs2874343 chr12:38239096 C/T cg26384229 chr12:38710491 ALG10B 0.87 10.81 0.5 1.21e-23 Bladder cancer; LIHC cis rs807029 0.577 rs750866 chr10:102761458 A/G cg25179470 chr10:102756915 LZTS2 0.42 5.73 0.3 2.22e-8 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00742472 chr14:31889912 NA -0.38 -6.67 -0.34 1.03e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4555082 0.874 rs1008628 chr14:105722726 T/C cg06808227 chr14:105710500 BRF1 -0.62 -8.45 -0.42 8.54e-16 Mean platelet volume;Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21668880 chr6:34759629 UHRF1BP1 0.46 6.36 0.33 6.5e-10 Lung function (FEV1/FVC); LIHC cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg03517284 chr6:25882590 NA 0.6 8.07 0.4 1.17e-14 Blood metabolite levels; LIHC trans rs1973993 0.967 rs1555543 chr1:96944797 A/C cg10631902 chr5:14652156 NA 0.28 6.43 0.33 4.26e-10 Weight; LIHC cis rs7647973 1.000 rs3870339 chr3:49536863 T/A cg07636037 chr3:49044803 WDR6 0.51 6.48 0.33 3.25e-10 Menarche (age at onset); LIHC cis rs6984305 0.541 rs17716118 chr8:9180134 A/G cg17371580 chr8:9182401 NA -0.36 -5.8 -0.3 1.52e-8 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7089973 0.604 rs1924034 chr10:116578539 C/T cg03647239 chr10:116582469 FAM160B1 0.44 6.29 0.32 9.8e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs6088580 0.524 rs1321306 chr20:33266379 T/A cg08999081 chr20:33150536 PIGU -0.43 -7.24 -0.36 2.89e-12 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.956 rs6591341 chr11:68335478 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.43 -0.33 4.33e-10 Total body bone mineral density; LIHC cis rs1552244 0.554 rs6762594 chr3:9995516 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.57 8.1 0.4 1.01e-14 Alzheimer's disease; LIHC cis rs1059312 1.000 rs7136092 chr12:129280164 G/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.73 -14.43 -0.62 3.3e-37 Systemic lupus erythematosus; LIHC cis rs249954 0.512 rs171617 chr16:23694774 A/T cg05131483 chr16:23706242 ERN2 0.37 6.04 0.31 3.95e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg23205692 chr1:25664452 TMEM50A 0.37 5.88 0.3 9.89e-9 Erythrocyte sedimentation rate; LIHC cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg09455208 chr3:40491958 NA 0.34 6.66 0.34 1.07e-10 Renal cell carcinoma; LIHC cis rs6088580 0.634 rs6088484 chr20:32985961 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.34 -0.58 5.73e-33 Glomerular filtration rate (creatinine); LIHC cis rs2243480 0.901 rs34807232 chr7:65965133 G/A cg05590025 chr7:65112418 INTS4L2 -0.55 -5.98 -0.31 5.61e-9 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs10510708 chr3:40404770 A/G cg00656387 chr3:40428638 ENTPD3 0.41 6.78 0.34 5.29e-11 Renal cell carcinoma; LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg12379764 chr21:47803548 PCNT -0.59 -8.55 -0.42 4.24e-16 Testicular germ cell tumor; LIHC cis rs8141529 0.764 rs5752812 chr22:29225603 T/A cg15103426 chr22:29168792 CCDC117 0.67 11.37 0.52 1.29e-25 Lymphocyte counts; LIHC cis rs9303401 0.580 rs12946396 chr17:57164195 T/A cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.29 0.55 5.1e-29 Cognitive test performance; LIHC cis rs61008539 0.586 rs6959154 chr7:856320 C/T cg11634705 chr7:873449 UNC84A 0.39 5.92 0.31 7.63e-9 Perceived unattractiveness to mosquitoes; LIHC cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg11062466 chr8:58055876 NA 0.48 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg09177884 chr7:1199841 ZFAND2A -0.42 -5.82 -0.3 1.32e-8 Longevity;Endometriosis; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg06873352 chr17:61820015 STRADA 0.72 12.69 0.57 1.65e-30 Prudent dietary pattern; LIHC cis rs2836974 0.583 rs9636957 chr21:40705847 G/A cg06238570 chr21:40685208 BRWD1 -0.51 -8.35 -0.41 1.75e-15 Cognitive function; LIHC cis rs1577917 0.959 rs2816822 chr6:86658292 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.19 -0.36 4.13e-12 Response to antipsychotic treatment; LIHC cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg13393036 chr8:95962371 TP53INP1 -0.45 -10.7 -0.5 3.08e-23 Type 2 diabetes; LIHC cis rs2153535 0.580 rs4960433 chr6:8523697 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.75 0.54 5.45e-27 Motion sickness; LIHC cis rs2425143 1.000 rs11696527 chr20:34245379 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.89 -0.3 9.45e-9 Blood protein levels; LIHC cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg06634786 chr22:41940651 POLR3H 0.75 7.95 0.39 2.76e-14 Vitiligo; LIHC cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg11764359 chr7:65958608 NA -0.58 -6.08 -0.31 3.14e-9 Diabetic kidney disease; LIHC cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.03 12.86 0.57 3.86e-31 Alzheimer's disease; LIHC trans rs4820294 0.669 rs732857 chr22:38060850 C/T cg19894588 chr14:64061835 NA -0.44 -6.88 -0.35 2.92e-11 Fat distribution (HIV); LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.75 0.62 1.8e-38 Prudent dietary pattern; LIHC cis rs2404602 0.735 rs11857327 chr15:76764263 G/C cg23625390 chr15:77176239 SCAPER -0.48 -8.03 -0.4 1.61e-14 Blood metabolite levels; LIHC cis rs6466055 0.777 rs10281886 chr7:104835888 T/C cg04380332 chr7:105027541 SRPK2 -0.35 -6.6 -0.34 1.52e-10 Schizophrenia; LIHC cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg00149659 chr3:10157352 C3orf10 0.54 5.93 0.31 7.37e-9 Alzheimer's disease; LIHC cis rs3008870 0.959 rs1886686 chr1:67390468 C/G cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.25e-8 Lymphocyte percentage of white cells; LIHC cis rs651907 0.514 rs10936744 chr3:101433440 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.47 -6.53 -0.33 2.41e-10 Colorectal cancer; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.23 0.81 4.46e-80 Prudent dietary pattern; LIHC cis rs6088580 0.634 rs6059892 chr20:33105766 A/G cg08999081 chr20:33150536 PIGU 0.67 13.46 0.59 1.89e-33 Glomerular filtration rate (creatinine); LIHC cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg06618935 chr21:46677482 NA -0.3 -5.76 -0.3 1.86e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8180040 0.701 rs7625067 chr3:47095305 T/C cg16586182 chr3:47516702 SCAP -0.5 -9.13 -0.44 6.03e-18 Colorectal cancer; LIHC cis rs4423214 1.000 rs4944955 chr11:71167677 C/T cg24826892 chr11:71159390 DHCR7 0.47 6.12 0.31 2.52e-9 Vitamin D levels; LIHC cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg09177884 chr7:1199841 ZFAND2A -0.43 -5.95 -0.31 6.63e-9 Longevity;Endometriosis; LIHC cis rs752010 0.714 rs6600384 chr1:42085141 A/G cg06885757 chr1:42089581 HIVEP3 -0.3 -6.33 -0.32 7.73e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs67311347 0.713 rs9861194 chr3:40309225 C/T cg18306943 chr3:40428807 ENTPD3 0.38 6.44 0.33 3.98e-10 Renal cell carcinoma; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.862 rs801194 chr7:66028495 T/C cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg06481639 chr22:41940642 POLR3H -0.7 -7.03 -0.36 1.14e-11 Vitiligo; LIHC cis rs875971 0.540 rs781152 chr7:65479572 T/A cg11764359 chr7:65958608 NA 0.67 8.8 0.43 7.12e-17 Aortic root size; LIHC cis rs7528419 1.000 rs7528419 chr1:109817192 A/G cg00908766 chr1:109817496 CELSR2 -0.48 -8.34 -0.41 1.83e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs1348850 0.540 rs6737342 chr2:178419117 G/A cg27490568 chr2:178487706 NA 0.71 7.48 0.38 6.24e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2404602 0.583 rs2469542 chr15:76557476 A/G cg22467129 chr15:76604101 ETFA 0.37 6.21 0.32 1.56e-9 Blood metabolite levels; LIHC cis rs561341 0.740 rs11080174 chr17:30208521 C/A cg13647721 chr17:30228624 UTP6 -0.7 -7.8 -0.39 7.58e-14 Hip circumference adjusted for BMI; LIHC cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg10802521 chr3:52805072 NEK4 -0.44 -7.41 -0.37 1.01e-12 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.615 rs11495518 chr12:38060505 A/G cg26384229 chr12:38710491 ALG10B 0.73 8.5 0.42 5.94e-16 Bladder cancer; LIHC cis rs34779708 0.931 rs35317849 chr10:35285721 C/A cg03585969 chr10:35415529 CREM 0.87 13.04 0.58 7.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1401454 1.000 rs1519125 chr11:16244588 G/C cg10927848 chr11:16298618 SOX6 -0.33 -6.12 -0.31 2.53e-9 Blood pressure; LIHC cis rs11098499 0.754 rs10212775 chr4:120239244 G/C cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs311392 0.525 rs366276 chr8:55100181 T/C cg11783602 chr8:55087084 NA -0.31 -6.16 -0.32 2.02e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs7772486 0.558 rs62435775 chr6:146136415 G/C cg05347473 chr6:146136440 FBXO30 0.46 6.89 0.35 2.69e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.863 rs7664986 chr4:120429952 A/C cg09307838 chr4:120376055 NA 0.77 11.95 0.54 9.51e-28 Corneal astigmatism; LIHC cis rs4665809 0.838 rs7565843 chr2:26292912 G/C cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.84 -0.43 5.01e-17 Gut microbiome composition (summer); LIHC cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg02353165 chr6:42928485 GNMT -0.55 -8.43 -0.41 9.94e-16 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs244293 0.965 rs244301 chr17:53239140 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.19 -0.36 4.2e-12 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13034943 chr12:132379564 ULK1 -0.42 -6.37 -0.33 6.01e-10 Pancreatic cancer; LIHC cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg02951883 chr7:2050386 MAD1L1 -0.62 -9.25 -0.45 2.55e-18 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs9399137 0.507 rs10484496 chr6:135299682 T/C cg24558204 chr6:135376177 HBS1L 0.61 10.33 0.49 6.2e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs853679 0.517 rs1904840 chr6:28108232 C/T cg16479474 chr6:28041457 NA 0.45 6.34 0.32 7.43e-10 Depression; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12566780 chr7:92157604 PEX1;C7orf64 0.41 6.11 0.31 2.65e-9 Lung function (FEV1/FVC); LIHC cis rs7772486 0.754 rs9390356 chr6:146118983 A/T cg23711669 chr6:146136114 FBXO30 -0.76 -13.77 -0.6 1.22e-34 Lobe attachment (rater-scored or self-reported); LIHC cis rs796364 0.616 rs7574313 chr2:200681040 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.16 0.32 2.03e-9 Schizophrenia; LIHC cis rs904251 0.522 rs882322 chr6:37484103 A/G cg08126542 chr6:37504118 NA -0.36 -6.16 -0.32 2.03e-9 Cognitive performance; LIHC cis rs6831352 0.918 rs17218108 chr4:100055755 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC trans rs7937682 0.961 rs11601674 chr11:111634354 C/T cg18187862 chr3:45730750 SACM1L 0.56 6.42 0.33 4.53e-10 Primary sclerosing cholangitis; LIHC cis rs7914558 0.966 rs1591915 chr10:104646849 C/T cg15744005 chr10:104629667 AS3MT -0.41 -9.3 -0.45 1.72e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2204008 0.713 rs2320522 chr12:38251438 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs2075671 0.857 rs11772849 chr7:100308412 G/A cg20848291 chr7:100343083 ZAN -0.45 -6.52 -0.33 2.55e-10 Other erythrocyte phenotypes; LIHC cis rs807669 0.903 rs1018764 chr22:19172006 T/C cg02655711 chr22:19163373 SLC25A1 0.73 11.4 0.52 9.96e-26 Metabolite levels; LIHC cis rs7044106 0.762 rs10760110 chr9:123412563 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.7 -11.45 -0.53 6.49e-26 Hip circumference adjusted for BMI; LIHC cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.91 0.35 2.34e-11 Gut microbiome composition (summer); LIHC cis rs796364 0.760 rs2881594 chr2:201026183 T/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -8.23 -0.41 3.99e-15 Schizophrenia; LIHC cis rs6918586 0.557 rs198827 chr6:26121002 C/T cg18357526 chr6:26021779 HIST1H4A -0.57 -8.45 -0.42 8.55e-16 Schizophrenia; LIHC cis rs950169 0.656 rs748455 chr15:85149575 T/C cg12863693 chr15:85201151 NMB 0.42 5.71 0.3 2.44e-8 Schizophrenia; LIHC cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg21724239 chr8:58056113 NA 0.59 7.56 0.38 3.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs8065963 chr17:37681332 C/T cg03013999 chr17:37608204 MED1 0.35 5.78 0.3 1.71e-8 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.865 rs10213221 chr4:120255926 G/A cg09307838 chr4:120376055 NA 0.69 10.62 0.5 5.94e-23 Corneal astigmatism; LIHC cis rs9303401 1.000 rs1390006 chr17:56890663 C/T cg12560992 chr17:57184187 TRIM37 -0.7 -10.49 -0.49 1.65e-22 Cognitive test performance; LIHC cis rs2839186 0.814 rs2839167 chr21:47661587 A/G cg12379764 chr21:47803548 PCNT -0.57 -8.35 -0.41 1.67e-15 Testicular germ cell tumor; LIHC cis rs7395581 0.959 rs59663860 chr11:47276350 G/C cg26139080 chr11:47293733 MADD -0.5 -8.53 -0.42 4.94e-16 HDL cholesterol; LIHC cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg06618935 chr21:46677482 NA -0.3 -5.76 -0.3 1.85e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7572733 0.534 rs700664 chr2:198671145 C/T cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.42e-11 Dermatomyositis; LIHC cis rs2760061 0.626 rs635563 chr1:228136834 C/T cg01200585 chr1:228362443 C1orf69 -0.4 -5.92 -0.31 7.63e-9 Diastolic blood pressure; LIHC cis rs9309473 0.950 rs6546854 chr2:73834034 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.44 -0.33 3.98e-10 Metabolite levels; LIHC cis rs875971 0.558 rs4433015 chr7:65639723 A/C cg14393609 chr7:65229607 NA -0.42 -6.12 -0.31 2.55e-9 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05281506 chr4:72052869 SLC4A4 0.48 6.95 0.35 1.88e-11 Pancreatic cancer; LIHC cis rs703842 0.575 rs701006 chr12:58106836 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.42 6.13 0.31 2.36e-9 Multiple sclerosis; LIHC cis rs2050392 0.624 rs303447 chr10:30728464 T/C cg18806716 chr10:30721971 MAP3K8 -0.41 -5.84 -0.3 1.22e-8 Inflammatory bowel disease; LIHC cis rs2455799 0.613 rs1393969 chr3:15730257 G/A cg12698662 chr3:15914712 MIR563 -0.37 -6.72 -0.34 7.42e-11 Mean platelet volume; LIHC cis rs2576037 0.526 rs10853547 chr18:44530548 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 10.98 0.51 3.17e-24 Personality dimensions; LIHC trans rs2797369 0.570 rs1928070 chr6:101583773 G/T cg04800749 chr22:50320996 CRELD2 0.35 6.05 0.31 3.76e-9 Renal function-related traits (eGRFcrea); LIHC cis rs4969178 0.896 rs1976704 chr17:76401318 C/T cg20026190 chr17:76395443 PGS1 0.45 7.12 0.36 6.46e-12 HDL cholesterol levels; LIHC cis rs9399135 0.967 rs9389261 chr6:135371148 C/G cg22676075 chr6:135203613 NA 0.4 6.36 0.33 6.58e-10 Red blood cell count; LIHC cis rs72781680 0.611 rs2303287 chr2:24302246 A/G cg06627628 chr2:24431161 ITSN2 0.64 7.43 0.37 8.57e-13 Lymphocyte counts; LIHC cis rs909341 0.903 rs1291205 chr20:62328829 C/G cg03999872 chr20:62272968 STMN3 -0.46 -6.78 -0.34 5.22e-11 Atopic dermatitis; LIHC cis rs7395581 0.877 rs7127907 chr11:47324472 A/C cg25783544 chr11:47291846 MADD 0.42 6.17 0.32 1.95e-9 HDL cholesterol; LIHC cis rs7727544 0.735 rs274557 chr5:131721204 T/C cg07395648 chr5:131743802 NA 0.33 6.9 0.35 2.57e-11 Blood metabolite levels; LIHC cis rs2153535 0.580 rs2143357 chr6:8497196 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.88 0.39 4.43e-14 Motion sickness; LIHC cis rs6504950 0.695 rs9904377 chr17:52985982 C/T cg10237252 chr17:52977213 TOM1L1 -0.42 -7.53 -0.38 4.44e-13 Breast cancer; LIHC cis rs240764 0.578 rs9498252 chr6:101194481 A/G cg09795085 chr6:101329169 ASCC3 0.42 6.28 0.32 1.01e-9 Neuroticism; LIHC cis rs10197940 0.571 rs13393021 chr2:152413258 A/C cg19508488 chr2:152266495 RIF1 0.63 9.35 0.45 1.17e-18 Lung cancer; LIHC cis rs9309473 1.000 rs7607014 chr2:73730174 C/T cg20560298 chr2:73613845 ALMS1 0.53 6.38 0.33 5.61e-10 Metabolite levels; LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg06420487 chr17:61919686 SMARCD2 0.42 5.81 0.3 1.41e-8 Height; LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg07308232 chr7:1071921 C7orf50 -0.4 -6.5 -0.33 2.79e-10 Longevity;Endometriosis; LIHC cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg06697600 chr4:7070879 GRPEL1 -0.66 -10.85 -0.51 9.17e-24 Monocyte percentage of white cells; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25622317 chr11:1002295 AP2A2 0.43 6.21 0.32 1.5e-9 Longevity; LIHC cis rs9325144 0.671 rs35817541 chr12:38975001 T/C cg26384229 chr12:38710491 ALG10B -0.42 -5.95 -0.31 6.72e-9 Morning vs. evening chronotype; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg06476606 chr10:91061728 IFIT2 0.48 6.98 0.35 1.56e-11 Morning vs. evening chronotype; LIHC cis rs8020095 0.528 rs73282769 chr14:67780267 A/G cg03487553 chr14:67822707 ATP6V1D -0.34 -5.84 -0.3 1.24e-8 Depression (quantitative trait); LIHC cis rs9768139 0.658 rs73746486 chr7:158113191 A/G cg25566285 chr7:158114605 PTPRN2 0.22 6.07 0.31 3.35e-9 Calcium levels; LIHC cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg03806693 chr22:41940476 POLR3H 0.98 11.7 0.53 7.98e-27 Vitiligo; LIHC cis rs2204008 0.714 rs11520135 chr12:38114863 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.65 0.5 4.53e-23 Bladder cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26541027 chr1:110163313 AMPD2 0.51 6.99 0.35 1.49e-11 Lung function (FEV1/FVC); LIHC cis rs4713118 0.513 rs156739 chr6:28013410 C/A cg16479474 chr6:28041457 NA 0.39 6.46 0.33 3.58e-10 Parkinson's disease; LIHC cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.47 0.49 1.98e-22 Vitiligo; LIHC cis rs116095464 0.614 rs4371799 chr5:268192 C/A cg22496380 chr5:211416 CCDC127 -1.03 -10.58 -0.5 8.03e-23 Breast cancer; LIHC cis rs9868809 0.505 rs11706983 chr3:48738678 A/G cg07636037 chr3:49044803 WDR6 -0.72 -7.57 -0.38 3.6e-13 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs4759375 0.915 rs7954704 chr12:123811371 G/A cg00376283 chr12:123451042 ABCB9 0.5 6.37 0.33 6.18e-10 HDL cholesterol; LIHC cis rs7208859 0.623 rs216439 chr17:28927884 T/C cg13385521 chr17:29058706 SUZ12P 0.69 6.62 0.34 1.36e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7917772 0.507 rs2778036 chr10:104485725 G/A cg22532475 chr10:104410764 TRIM8 -0.36 -6.1 -0.31 2.84e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs10506458 1.000 rs12580997 chr12:63433420 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.76 -10.84 -0.51 9.66e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs7552404 0.924 rs1498317 chr1:76171984 A/C cg22875332 chr1:76189707 ACADM 0.49 7.61 0.38 2.67e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4689388 0.926 rs10012946 chr4:6293350 C/T cg14416269 chr4:6271139 WFS1 -0.45 -6.27 -0.32 1.11e-9 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs10751667 0.666 rs7396677 chr11:958878 C/T cg06064525 chr11:970664 AP2A2 -0.56 -15.02 -0.63 1.63e-39 Alzheimer's disease (late onset); LIHC cis rs1577917 0.545 rs1335443 chr6:86478737 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.33 -6.17 -0.32 1.98e-9 Response to antipsychotic treatment; LIHC cis rs6088580 0.524 rs6088569 chr20:33268199 G/A cg08999081 chr20:33150536 PIGU -0.43 -7.24 -0.36 3e-12 Glomerular filtration rate (creatinine); LIHC cis rs8058578 1.000 rs2289442 chr16:30739919 A/G cg00531865 chr16:30841666 NA -0.38 -6.07 -0.31 3.39e-9 Multiple myeloma; LIHC cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg03264133 chr6:25882463 NA -0.53 -6.49 -0.33 3.03e-10 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.875 rs2777483 chr6:146329235 A/G cg13319975 chr6:146136371 FBXO30 -0.37 -6.11 -0.31 2.71e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs1538970 0.962 rs9429160 chr1:45827968 G/T cg24296786 chr1:45957014 TESK2 -0.49 -7.31 -0.37 1.96e-12 Platelet count; LIHC cis rs4906332 0.966 rs7401563 chr14:103964425 G/A cg19000871 chr14:103996768 TRMT61A -0.47 -7.88 -0.39 4.35e-14 Coronary artery disease; LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg10096929 chr1:156261403 TMEM79 0.4 6.73 0.34 7.35e-11 Tonsillectomy; LIHC cis rs8017423 0.647 rs12895269 chr14:90822430 T/C cg04374321 chr14:90722782 PSMC1 -0.49 -7.26 -0.37 2.56e-12 Mortality in heart failure; LIHC cis rs7937682 0.921 rs4616071 chr11:111440865 C/G cg09085632 chr11:111637200 PPP2R1B 0.88 9.84 0.47 2.72e-20 Primary sclerosing cholangitis; LIHC cis rs9640161 0.830 rs3757425 chr7:150067640 A/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -8.19 -0.41 5.1e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs380904 1.000 rs12543128 chr8:144595042 G/A cg20583945 chr8:144636462 GSDMD 0.6 8.7 0.43 1.42e-16 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs986417 0.892 rs11622577 chr14:60814981 A/T cg27398547 chr14:60952738 C14orf39 -0.78 -8.72 -0.43 1.25e-16 Gut microbiota (bacterial taxa); LIHC cis rs16828019 0.852 rs35992757 chr1:41652862 C/T cg20697417 chr1:41786797 NA 0.35 6.65 0.34 1.15e-10 Intelligence (multi-trait analysis); LIHC cis rs903552 0.935 rs12907726 chr15:102003626 C/G cg06707286 chr15:102010195 PCSK6 -0.44 -6.33 -0.32 7.48e-10 Diabetic kidney disease; LIHC cis rs6430585 0.583 rs11886852 chr2:136589379 G/A cg07169764 chr2:136633963 MCM6 1.04 16.14 0.66 5.73e-44 Corneal structure; LIHC cis rs1005277 0.529 rs1780125 chr10:38531376 A/G cg25427524 chr10:38739819 LOC399744 -0.76 -15.25 -0.64 2.01e-40 Extrinsic epigenetic age acceleration; LIHC cis rs67311347 1.000 rs11716675 chr3:40485280 G/T cg13409248 chr3:40428643 ENTPD3 0.41 6.9 0.35 2.58e-11 Renal cell carcinoma; LIHC cis rs4820294 1.000 rs62236668 chr22:38063870 G/A cg00292662 chr22:38071168 LGALS1 0.63 9.9 0.47 1.69e-20 Fat distribution (HIV); LIHC cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.52 -0.56 7.42e-30 Alzheimer's disease; LIHC cis rs2576037 0.526 rs607780 chr18:44417456 C/T cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 2.04e-10 Personality dimensions; LIHC cis rs875971 0.545 rs316324 chr7:65610614 A/G cg11764359 chr7:65958608 NA -0.52 -7.1 -0.36 7.24e-12 Aortic root size; LIHC cis rs7729447 0.776 rs17540155 chr5:32694033 C/T cg16267343 chr5:32710456 NPR3 0.48 5.86 0.3 1.09e-8 Blood pressure; LIHC cis rs9640161 0.659 rs17837498 chr7:150009679 A/G cg10018233 chr7:150070692 REPIN1 0.5 8.19 0.4 5.27e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg18279126 chr7:2041391 MAD1L1 0.36 5.99 0.31 5.22e-9 Bipolar disorder and schizophrenia; LIHC cis rs7659604 0.540 rs10020581 chr4:122676559 A/C cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.7e-11 Type 2 diabetes; LIHC cis rs6089584 0.566 rs2181589 chr20:60622817 C/T cg06108461 chr20:60628389 TAF4 0.65 9.04 0.44 1.22e-17 Body mass index; LIHC cis rs7577696 0.554 rs3769605 chr2:32322456 A/G cg02381751 chr2:32503542 YIPF4 -0.47 -6.53 -0.33 2.35e-10 Inflammatory biomarkers; LIHC trans rs877282 0.583 rs11595057 chr10:819203 A/C cg22713356 chr15:30763199 NA 0.77 6.81 0.35 4.28e-11 Uric acid levels; LIHC cis rs10492096 0.945 rs1045546 chr12:6567907 C/T cg13857086 chr12:6580257 VAMP1 0.59 5.97 0.31 6.06e-9 Hip geometry; LIHC cis rs244293 0.965 rs244312 chr17:53213197 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.37 -0.37 1.27e-12 Menarche (age at onset); LIHC trans rs2262909 0.962 rs55728714 chr19:22262899 A/G cg17074339 chr11:11642133 GALNTL4 0.4 6.06 0.31 3.65e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC trans rs2739330 0.731 rs4822450 chr22:24242887 C/T cg06437703 chr8:37914619 EIF4EBP1 -0.56 -8.48 -0.42 6.93e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs61774743 0.754 rs11578963 chr1:41834183 A/G cg08462924 chr1:41848221 NA -0.39 -6.45 -0.33 3.74e-10 Intelligence (multi-trait analysis); LIHC cis rs2295359 0.892 rs11209005 chr1:67618678 A/G cg12940439 chr1:67600707 NA 0.4 7.18 0.36 4.4e-12 Psoriasis; LIHC cis rs1144333 0.510 rs1146652 chr1:76273708 A/G cg10523679 chr1:76189770 ACADM -0.44 -6.01 -0.31 4.66e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg11644478 chr21:40555479 PSMG1 -0.45 -7.05 -0.36 1.01e-11 Cognitive function; LIHC cis rs735396 1.000 rs1169310 chr12:121439433 G/A cg25281562 chr12:121454272 C12orf43 0.33 5.74 0.3 2.08e-8 N-glycan levels; LIHC trans rs1005277 0.579 rs1740745 chr10:38520056 T/C cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs5769765 0.908 rs9616370 chr22:50306316 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.86 10.58 0.5 8.25e-23 Schizophrenia; LIHC cis rs7258465 1.000 rs10164319 chr19:18569833 G/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.51 -0.38 5.29e-13 Breast cancer; LIHC cis rs6466055 0.748 rs1204080 chr7:104988848 A/G cg04380332 chr7:105027541 SRPK2 0.37 6.91 0.35 2.32e-11 Schizophrenia; LIHC cis rs7772486 0.875 rs10872582 chr6:146373061 G/A cg23711669 chr6:146136114 FBXO30 0.59 10.65 0.5 4.73e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg17328964 chr8:145687451 CYHR1 0.48 7.93 0.39 3.11e-14 Age at first birth; LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg07308232 chr7:1071921 C7orf50 -0.42 -6.63 -0.34 1.28e-10 Longevity;Endometriosis; LIHC cis rs2841277 0.676 rs10438247 chr14:105411781 G/A cg15352829 chr14:105391018 PLD4 -0.43 -9.16 -0.44 4.97e-18 Rheumatoid arthritis; LIHC cis rs7618501 0.633 rs6446193 chr3:50059758 T/C cg21467203 chr3:49911342 NA 0.44 7.87 0.39 4.61e-14 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.641 rs2591954 chr5:56245044 G/C cg12311346 chr5:56204834 C5orf35 0.44 5.99 0.31 5.44e-9 Initial pursuit acceleration; LIHC cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs3617 0.573 rs9880978 chr3:52923251 C/G cg11645453 chr3:52864694 ITIH4 0.23 6.12 0.31 2.58e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs13256369 1.000 rs4841017 chr8:8577093 A/G cg18904891 chr8:8559673 CLDN23 0.66 11.16 0.52 7.31e-25 Obesity-related traits; LIHC cis rs6952808 0.601 rs3800882 chr7:2120758 G/A cg02951883 chr7:2050386 MAD1L1 -0.62 -10.1 -0.48 3.74e-21 Bipolar disorder and schizophrenia; LIHC cis rs2239547 0.657 rs7620706 chr3:52891756 A/T cg18404041 chr3:52824283 ITIH1 -0.46 -6.35 -0.32 6.75e-10 Schizophrenia; LIHC cis rs7903847 0.620 rs954149 chr10:99122936 G/A cg20016023 chr10:99160130 RRP12 -0.41 -6.34 -0.32 7.3e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1008375 1.000 rs10011865 chr4:17645710 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.9 0.3 8.54e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs332507 0.789 rs13064861 chr3:124352236 A/G cg05980111 chr3:124395277 KALRN 0.38 6.15 0.32 2.13e-9 Plateletcrit; LIHC cis rs10463316 0.832 rs246482 chr5:150731857 C/G cg03212797 chr5:150827313 SLC36A1 -0.44 -6.78 -0.34 5.42e-11 Metabolite levels (Pyroglutamine); LIHC cis rs35110281 0.633 rs4819292 chr21:45125223 A/G cg04455712 chr21:45112962 RRP1B 0.51 8.96 0.44 2.13e-17 Mean corpuscular volume; LIHC cis rs2933343 0.729 rs813945 chr3:128660937 A/G cg25356066 chr3:128598488 ACAD9 0.52 7.15 0.36 5.21e-12 IgG glycosylation; LIHC cis rs875971 0.862 rs12537823 chr7:65720884 C/T cg11764359 chr7:65958608 NA 0.84 14.85 0.63 7.54e-39 Aortic root size; LIHC cis rs9911578 1.000 rs8071916 chr17:56660279 A/G cg12560992 chr17:57184187 TRIM37 0.95 17.37 0.68 6.45e-49 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg14004847 chr7:1930337 MAD1L1 0.45 6.71 0.34 8.03e-11 Bipolar disorder and schizophrenia; LIHC cis rs2576037 0.583 rs530205 chr18:44385150 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -6.86 -0.35 3.17e-11 Personality dimensions; LIHC trans rs11148252 0.840 rs4369550 chr13:52744910 A/G cg18335740 chr13:41363409 SLC25A15 0.37 6.3 0.32 9.27e-10 Lewy body disease; LIHC cis rs738322 1.000 rs4382 chr22:38570842 T/C cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 11.5 0.53 4.16e-26 Height; LIHC cis rs703842 0.642 rs11536137 chr12:58056426 C/A cg15848620 chr12:58087721 OS9 0.49 6.16 0.32 2e-9 Multiple sclerosis; LIHC cis rs8060686 0.516 rs4640173 chr16:68163602 C/A cg05110241 chr16:68378359 PRMT7 -0.53 -6.21 -0.32 1.5e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs9291683 0.588 rs3756238 chr4:10013202 C/T cg11266682 chr4:10021025 SLC2A9 0.33 7.14 0.36 5.5e-12 Bone mineral density; LIHC cis rs61863818 0.557 rs7898743 chr10:99153540 T/G cg06359132 chr10:99160096 RRP12 -0.36 -5.94 -0.31 6.95e-9 Monocyte percentage of white cells; LIHC cis rs17401966 0.838 rs12737239 chr1:10323973 C/G cg15208524 chr1:10270712 KIF1B 0.39 5.99 0.31 5.17e-9 Hepatocellular carcinoma; LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg09455208 chr3:40491958 NA 0.39 7.8 0.39 7.76e-14 Renal cell carcinoma; LIHC cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg16405210 chr4:1374714 KIAA1530 -0.65 -9.67 -0.46 1.02e-19 Longevity; LIHC cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg06634786 chr22:41940651 POLR3H 0.73 7.56 0.38 3.68e-13 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21866054 chr4:103748674 UBE2D3 0.46 7.03 0.36 1.14e-11 Pancreatic cancer; LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs6121246 0.523 rs6060286 chr20:30197663 C/A cg13852791 chr20:30311386 BCL2L1 0.76 6.82 0.35 4.02e-11 Mean corpuscular hemoglobin; LIHC cis rs17685 0.725 rs6467993 chr7:75719350 G/A cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.89e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC cis rs4319547 0.695 rs1973463 chr12:122938003 A/G cg23029597 chr12:123009494 RSRC2 -0.5 -7.01 -0.35 1.28e-11 Body mass index; LIHC cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg18306943 chr3:40428807 ENTPD3 0.36 6.16 0.32 2.03e-9 Renal cell carcinoma; LIHC cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg05564831 chr3:52568323 NT5DC2 0.39 6.29 0.32 9.51e-10 Bipolar disorder; LIHC cis rs911119 1.000 rs1010117 chr20:23608421 G/C cg16589663 chr20:23618590 CST3 0.74 7.76 0.39 1.01e-13 Chronic kidney disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg21250466 chr4:854474 GAK 0.49 6.56 0.33 2.01e-10 Hepatitis; LIHC cis rs3768617 0.510 rs2296290 chr1:183079412 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.66 0.5 4.09e-23 Fuchs's corneal dystrophy; LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.959 rs6433314 chr2:172660971 A/G cg13550731 chr2:172543902 DYNC1I2 -0.95 -18.14 -0.7 5.18e-52 Schizophrenia; LIHC cis rs12477438 1.000 rs17760953 chr2:99859863 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.03 -12.31 -0.55 4.52e-29 Chronic sinus infection; LIHC cis rs2834188 1.000 rs2409488 chr21:34688914 A/C cg14352951 chr21:34696688 IFNAR1 0.47 6.49 0.33 2.95e-10 Narcolepsy; LIHC cis rs3106136 0.934 rs2902979 chr4:95177874 C/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.88 -0.39 4.27e-14 Capecitabine sensitivity; LIHC cis rs9611565 0.570 rs12159188 chr22:42121125 A/T cg03806693 chr22:41940476 POLR3H 0.76 8.73 0.43 1.13e-16 Vitiligo; LIHC cis rs903552 1.000 rs12906575 chr15:102003617 G/A cg19295451 chr15:102010161 PCSK6 -0.44 -6.08 -0.31 3.14e-9 Diabetic kidney disease; LIHC cis rs2637266 0.599 rs2395425 chr10:78461920 C/T cg18941641 chr10:78392320 NA 0.27 5.73 0.3 2.2e-8 Pulmonary function; LIHC cis rs9916302 0.595 rs4795371 chr17:37636695 T/G cg07936489 chr17:37558343 FBXL20 -0.84 -13.15 -0.58 2.94e-32 Glomerular filtration rate (creatinine); LIHC cis rs2066819 1.000 rs59626664 chr12:56636975 C/G cg26734620 chr12:56694298 CS 1.23 10.54 0.5 1.14e-22 Psoriasis vulgaris; LIHC cis rs903552 0.736 rs2132196 chr15:102007089 A/G cg25677261 chr15:102009856 PCSK6 -0.51 -7.0 -0.35 1.36e-11 Diabetic kidney disease; LIHC cis rs425277 0.585 rs2222217 chr1:2063164 G/A cg04315214 chr1:2043799 PRKCZ 0.44 6.61 0.34 1.48e-10 Height; LIHC cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg08888203 chr3:10149979 C3orf24 0.61 6.92 0.35 2.29e-11 Alzheimer's disease; LIHC cis rs7116495 0.786 rs4479013 chr11:71673732 C/G cg26138937 chr11:71823887 C11orf51 -0.82 -8.17 -0.4 6.02e-15 Severe influenza A (H1N1) infection; LIHC cis rs9303280 0.742 rs11557466 chr17:38024626 C/T cg11212589 chr17:38028394 ZPBP2 0.35 6.97 0.35 1.65e-11 Self-reported allergy; LIHC cis rs12711979 0.509 rs10200764 chr2:3827772 C/G cg17052675 chr2:3827356 NA -0.72 -16.2 -0.66 3.33e-44 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs11098499 0.618 rs6858383 chr4:120296772 T/C cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs28595532 0.702 rs72670238 chr4:119322751 C/T cg21605333 chr4:119757512 SEC24D 0.86 7.22 0.36 3.48e-12 Cannabis dependence symptom count; LIHC cis rs35892873 0.959 rs9845572 chr3:126092217 C/T cg15490784 chr3:126061950 KLF15 0.45 6.68 0.34 9.7e-11 Male-pattern baldness; LIHC cis rs1577917 0.958 rs13213551 chr6:86608701 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC trans rs1814175 0.645 rs10769605 chr11:49713723 A/G cg03929089 chr4:120376271 NA -0.86 -16.65 -0.67 5.35e-46 Height; LIHC trans rs7395662 0.500 rs1605360 chr11:48685714 G/A cg15704280 chr7:45808275 SEPT13 -0.49 -7.45 -0.37 7.47e-13 HDL cholesterol; LIHC cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg05025164 chr4:1340916 KIAA1530 -0.4 -6.08 -0.31 3.14e-9 Obesity-related traits; LIHC cis rs11105298 0.891 rs11105316 chr12:89925200 T/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.27 -0.37 2.4e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10751667 0.961 rs7943115 chr11:973885 T/C cg10932868 chr11:921992 NA 0.36 6.72 0.34 7.52e-11 Alzheimer's disease (late onset); LIHC cis rs2153535 0.607 rs9502722 chr6:8541483 C/T cg21535247 chr6:8435926 SLC35B3 0.64 8.23 0.41 4.04e-15 Motion sickness; LIHC cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg13770153 chr20:60521292 NA -0.35 -7.09 -0.36 7.73e-12 Body mass index; LIHC cis rs2303745 0.589 rs7246262 chr19:17392483 C/G cg10664184 chr19:17420304 DDA1 0.46 5.87 0.3 1.03e-8 Systemic lupus erythematosus; LIHC cis rs9303401 0.580 rs34076823 chr17:57114497 C/G cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.33 0.55 3.79e-29 Cognitive test performance; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00929392 chr1:19283191 IFFO2 -0.47 -6.47 -0.33 3.44e-10 Longevity; LIHC cis rs708547 0.647 rs2293175 chr4:57861358 C/T cg25525207 chr4:57843836 C4orf14;POLR2B -0.43 -6.66 -0.34 1.1e-10 Response to bleomycin (chromatid breaks); LIHC cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg00750074 chr16:89608354 SPG7 -0.38 -5.75 -0.3 1.93e-8 Multiple myeloma (IgH translocation); LIHC cis rs7918232 0.882 rs2149413 chr10:27430311 C/T cg14240646 chr10:27532245 ACBD5 0.69 6.4 0.33 5.12e-10 Breast cancer; LIHC cis rs1043515 0.935 rs2338115 chr17:36929578 C/T cg20826740 chr17:37024042 NA 0.36 5.79 0.3 1.56e-8 Height; LIHC cis rs6502050 0.871 rs8072702 chr17:80074280 C/T cg11859384 chr17:80120422 CCDC57 0.42 5.8 0.3 1.51e-8 Life satisfaction; LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg06558623 chr16:89946397 TCF25 0.88 13.68 0.59 2.77e-34 Skin colour saturation; LIHC cis rs7208859 0.673 rs216424 chr17:28943064 T/G cg14067834 chr17:29058358 SUZ12P 0.6 6.24 0.32 1.27e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg18306943 chr3:40428807 ENTPD3 0.34 5.76 0.3 1.88e-8 Renal cell carcinoma; LIHC trans rs11098499 0.909 rs7681978 chr4:120383775 T/C cg25214090 chr10:38739885 LOC399744 0.61 10.02 0.48 7.11e-21 Corneal astigmatism; LIHC cis rs7843479 0.601 rs10101881 chr8:21830158 A/G cg17168535 chr8:21777572 XPO7 0.6 9.37 0.45 1.03e-18 Mean corpuscular volume; LIHC cis rs12586317 0.547 rs114371385 chr14:35503724 G/A cg05294307 chr14:35346193 BAZ1A -0.5 -7.53 -0.38 4.65e-13 Psoriasis; LIHC cis rs7395581 0.775 rs2269434 chr11:47360412 T/C cg26139080 chr11:47293733 MADD -0.49 -8.26 -0.41 3.31e-15 HDL cholesterol; LIHC cis rs8062405 0.964 rs11860513 chr16:28825420 C/T cg07451762 chr16:28383216 NA 0.34 6.47 0.33 3.31e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7635838 0.892 rs9838141 chr3:11488639 C/T cg00170343 chr3:11313890 ATG7 0.43 6.7 0.34 8.63e-11 HDL cholesterol; LIHC cis rs9828933 1.000 rs1060897 chr3:63997872 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.71 9.13 0.44 5.89e-18 Type 2 diabetes; LIHC cis rs72781680 0.821 rs72796369 chr2:24162663 G/T cg08917208 chr2:24149416 ATAD2B 0.65 6.57 0.33 1.86e-10 Lymphocyte counts; LIHC cis rs7617773 0.784 rs9850672 chr3:48301172 C/A cg11946769 chr3:48343235 NME6 0.87 11.2 0.52 5e-25 Coronary artery disease; LIHC cis rs992157 0.835 rs11677953 chr2:219121663 G/A cg00012203 chr2:219082015 ARPC2 -0.86 -13.79 -0.6 1.05e-34 Colorectal cancer; LIHC cis rs9467773 1.000 rs6940053 chr6:26562122 C/T cg09904177 chr6:26538194 HMGN4 0.65 13.64 0.59 3.82e-34 Intelligence (multi-trait analysis); LIHC cis rs1144333 0.655 rs76735776 chr1:76455211 A/G cg03433033 chr1:76189801 ACADM 0.54 7.51 0.38 5.03e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs875971 1.000 rs2420168 chr7:65630631 C/G cg11764359 chr7:65958608 NA -0.88 -15.37 -0.64 6.43e-41 Aortic root size; LIHC cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 6.91 0.35 2.31e-11 Bipolar disorder; LIHC trans rs11098499 0.954 rs6822679 chr4:120402702 A/C cg25214090 chr10:38739885 LOC399744 0.58 9.5 0.46 3.69e-19 Corneal astigmatism; LIHC cis rs8072100 0.967 rs4793842 chr17:45671506 G/A cg08085267 chr17:45401833 C17orf57 0.41 6.11 0.31 2.68e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs13191362 1.000 rs35383933 chr6:163002869 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9464760 0.527 rs9476757 chr6:15157289 A/G cg15799072 chr6:15248335 JARID2 0.6 5.9 0.3 8.63e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6450176 1.000 rs6876198 chr5:53303595 A/G ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.21 -0.64 2.78e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2404602 0.647 rs11631959 chr15:77040048 T/C cg23625390 chr15:77176239 SCAPER -0.56 -9.47 -0.46 4.6e-19 Blood metabolite levels; LIHC cis rs738321 0.757 rs3788536 chr22:38534209 C/T cg25457927 chr22:38595422 NA -0.31 -6.92 -0.35 2.27e-11 Breast cancer; LIHC cis rs11122272 0.735 rs2808595 chr1:231526238 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.52 -0.49 1.34e-22 Hemoglobin concentration; LIHC cis rs2153535 0.541 rs9328471 chr6:8468842 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs9814567 1.000 rs9864439 chr3:134298671 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.26 -0.32 1.13e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8180040 0.966 rs17784882 chr3:47544003 C/A cg16586182 chr3:47516702 SCAP 0.47 8.18 0.4 5.46e-15 Colorectal cancer; LIHC cis rs965469 1.000 rs6051779 chr20:3333449 A/G cg25506879 chr20:3388711 C20orf194 -0.57 -6.88 -0.35 2.95e-11 IFN-related cytopenia; LIHC cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg18252515 chr7:66147081 NA 1.28 17.42 0.69 4.2e-49 Diabetic kidney disease; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs929354 0.772 rs6459737 chr7:156975136 G/A cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs1873147 0.569 rs59418037 chr15:63310871 A/G cg05771511 chr15:63340396 TPM1 -0.44 -5.94 -0.31 7.01e-9 Orofacial clefts; LIHC cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg04317338 chr11:64019027 PLCB3 0.88 11.0 0.51 2.73e-24 Mean platelet volume; LIHC cis rs600806 0.778 rs4970765 chr1:110009171 C/T cg16275483 chr1:110013120 SYPL2 -0.49 -6.15 -0.32 2.16e-9 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg04944784 chr2:26401820 FAM59B -0.73 -9.24 -0.45 2.78e-18 Gut microbiome composition (summer); LIHC cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.65 -0.38 2.11e-13 Bipolar disorder; LIHC cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg03806693 chr22:41940476 POLR3H 0.99 10.62 0.5 5.84e-23 Cannabis dependence symptom count; LIHC cis rs9733 0.688 rs12725667 chr1:150766070 A/T cg18016565 chr1:150552671 MCL1 -0.48 -9.33 -0.45 1.33e-18 Tonsillectomy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02685901 chr6:43597772 MAD2L1BP;GTPBP2 0.44 7.25 0.36 2.8e-12 Cognitive function; LIHC cis rs1401999 1.000 rs7632670 chr3:183713877 A/G cg01324343 chr3:183735012 ABCC5 0.76 12.98 0.57 1.34e-31 Anterior chamber depth; LIHC cis rs12579753 0.879 rs11115002 chr12:82153090 C/T cg07988820 chr12:82153109 PPFIA2 -0.48 -5.83 -0.3 1.28e-8 Resting heart rate; LIHC cis rs11098499 0.644 rs10009566 chr4:120558608 A/G cg09307838 chr4:120376055 NA 0.67 10.09 0.48 4.04e-21 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08204369 chr17:73150733 HN1 0.49 7.52 0.38 4.73e-13 Pancreatic cancer; LIHC cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg11644478 chr21:40555479 PSMG1 -0.82 -10.76 -0.5 1.86e-23 Cognitive function; LIHC cis rs17106184 1.000 rs72902772 chr1:51265368 C/T cg07174182 chr1:51127561 FAF1 -0.65 -6.99 -0.35 1.46e-11 Type 2 diabetes; LIHC cis rs9303401 1.000 rs9303401 chr17:56847945 C/T cg05425664 chr17:57184151 TRIM37 -0.53 -7.51 -0.38 5.17e-13 Cognitive test performance; LIHC cis rs2075371 0.796 rs1643040 chr7:134011703 G/C cg20476274 chr7:133979776 SLC35B4 0.62 10.32 0.49 6.23e-22 Mean platelet volume; LIHC cis rs6539247 0.542 rs880298 chr12:106443134 C/T cg20883310 chr12:106464547 NUAK1 0.43 6.96 0.35 1.7e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs644799 1.000 rs3748256 chr11:95521953 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.54e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2404618 0.624 rs7012381 chr8:1475357 C/T cg22787604 chr8:1509810 DLGAP2 -0.33 -5.73 -0.3 2.22e-8 Lung cancer; LIHC cis rs17094222 0.812 rs17113328 chr10:102435953 T/G cg26540559 chr10:102447443 NA 0.32 6.15 0.32 2.17e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs13161895 0.702 rs12652904 chr5:179496422 C/T cg06664874 chr5:179499304 RNF130 0.7 7.62 0.38 2.55e-13 LDL cholesterol; LIHC cis rs1865721 0.771 rs6566093 chr18:73136682 T/C cg26385618 chr18:73139727 C18orf62 -0.32 -8.71 -0.43 1.35e-16 Intelligence; LIHC cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg11645453 chr3:52864694 ITIH4 0.21 5.83 0.3 1.26e-8 Bipolar disorder; LIHC trans rs1814175 0.754 rs10839453 chr11:49955815 A/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.55e-73 Height; LIHC cis rs933688 1.000 rs10058025 chr5:90689052 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.69 0.73 3.11e-58 Smoking behavior; LIHC cis rs2286503 0.780 rs929464 chr7:22874770 T/C cg11367502 chr7:22862612 TOMM7 0.48 8.42 0.41 1.04e-15 Fibrinogen; LIHC cis rs9322193 0.607 rs6557165 chr6:150228019 C/G cg01145232 chr6:150245071 RAET1G -0.34 -6.94 -0.35 1.94e-11 Lung cancer; LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg21782813 chr7:2030301 MAD1L1 0.42 7.06 0.36 9.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs7107174 1.000 rs7116611 chr11:78030046 A/G cg02023728 chr11:77925099 USP35 0.53 10.11 0.48 3.39e-21 Testicular germ cell tumor; LIHC cis rs11628318 0.614 rs1190342 chr14:103100382 C/T cg01864069 chr14:103024347 NA -0.46 -7.35 -0.37 1.5e-12 Platelet count; LIHC cis rs734999 0.967 rs6667605 chr1:2502780 C/T cg18854424 chr1:2615690 NA 0.32 6.75 0.34 6.43e-11 Ulcerative colitis; LIHC cis rs10876993 0.928 rs813854 chr12:58071347 A/G cg15848620 chr12:58087721 OS9 -0.58 -8.02 -0.4 1.65e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg12310025 chr6:25882481 NA -0.53 -6.38 -0.33 5.77e-10 Intelligence (multi-trait analysis); LIHC cis rs769267 0.895 rs2965183 chr19:19545696 G/A cg03709012 chr19:19516395 GATAD2A 1.03 18.46 0.71 2.67e-53 Tonsillectomy; LIHC cis rs7959452 0.590 rs11177644 chr12:69785748 A/G cg20891283 chr12:69753455 YEATS4 0.89 19.47 0.72 2.46e-57 Blood protein levels; LIHC cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9915021 0.623 rs9899927 chr17:33949083 T/G cg20932281 chr17:33905541 PEX12 0.61 7.52 0.38 4.73e-13 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs7116495 0.881 rs1939243 chr11:71742735 A/G cg10381502 chr11:71823885 C11orf51 0.56 5.84 0.3 1.18e-8 Severe influenza A (H1N1) infection; LIHC cis rs9513627 0.665 rs79036236 chr13:100116405 C/T cg25919922 chr13:100150906 NA -0.76 -6.41 -0.33 4.7e-10 Obesity-related traits; LIHC cis rs116248771 0.739 rs73156478 chr3:158398716 C/T cg16708174 chr3:158430962 RARRES1 0.49 6.53 0.33 2.32e-10 diarrhoeal disease at age 2; LIHC cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4665809 1.000 rs4665809 chr2:26251361 C/T cg27170947 chr2:26402098 FAM59B 0.67 8.3 0.41 2.47e-15 Gut microbiome composition (summer); LIHC cis rs2921073 0.605 rs2976933 chr8:8254875 A/G cg15556689 chr8:8085844 FLJ10661 0.44 6.12 0.31 2.57e-9 Parkinson's disease; LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg14709524 chr16:89940631 TCF25 0.53 6.44 0.33 4.03e-10 Skin colour saturation; LIHC trans rs9929218 0.954 rs4485355 chr16:68754730 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.6 -9.16 -0.44 4.8e-18 Colorectal cancer; LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg07308232 chr7:1071921 C7orf50 -0.39 -6.34 -0.32 7.34e-10 Longevity;Endometriosis; LIHC cis rs7552404 0.960 rs61797339 chr1:76189946 G/T cg10523679 chr1:76189770 ACADM 0.64 8.78 0.43 7.87e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.41e-8 Menopause (age at onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg19478983 chr7:120590592 ING3 -0.44 -6.81 -0.35 4.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs317689 0.600 rs478188 chr12:69639215 A/G cg14784868 chr12:69753453 YEATS4 0.51 6.94 0.35 2e-11 Response to diuretic therapy; LIHC cis rs3020736 0.500 rs6519306 chr22:42501217 T/C cg04733989 chr22:42467013 NAGA -0.66 -9.44 -0.45 5.76e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9393692 0.905 rs7450556 chr6:26299900 C/T cg05868516 chr6:26286170 HIST1H4H 0.4 6.07 0.31 3.45e-9 Educational attainment; LIHC cis rs4689592 0.554 rs3951346 chr4:7073321 C/T cg26116260 chr4:7069785 GRPEL1 0.99 18.78 0.71 1.38e-54 Monocyte percentage of white cells; LIHC cis rs10508774 0.810 rs11008979 chr10:32860267 A/G cg01819863 chr10:32635814 EPC1 0.61 5.83 0.3 1.31e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9549367 0.713 rs3024757 chr13:113823186 G/T cg18105134 chr13:113819100 PROZ -0.74 -12.12 -0.55 2.34e-28 Platelet distribution width; LIHC trans rs9858542 1.000 rs11130213 chr3:49712297 C/T cg21659725 chr3:3221576 CRBN -0.54 -6.11 -0.31 2.65e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg19318889 chr4:1322082 MAEA -0.48 -7.95 -0.39 2.82e-14 Obesity-related traits; LIHC cis rs11690935 0.959 rs10207085 chr2:172585885 T/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.71 -0.69 2.99e-50 Schizophrenia; LIHC cis rs6951245 1.000 rs2363286 chr7:1091625 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.74 5.93 0.31 7.55e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2836974 0.644 rs9978775 chr21:40694526 A/G cg17971929 chr21:40555470 PSMG1 -0.43 -6.27 -0.32 1.06e-9 Cognitive function; LIHC cis rs7224685 0.569 rs965515 chr17:4038149 G/A cg09597638 chr17:3907349 NA 0.55 6.69 0.34 9.08e-11 Type 2 diabetes; LIHC cis rs7666738 0.512 rs6532704 chr4:98777562 C/T cg05340658 chr4:99064831 C4orf37 0.39 5.9 0.3 8.9e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs9309473 1.000 rs10187416 chr2:73713741 T/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.66 -0.34 1.12e-10 Metabolite levels; LIHC cis rs796364 0.806 rs112486506 chr2:201073947 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.68 -7.24 -0.36 2.91e-12 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25739137 chr3:183851986 EIF2B5 -0.44 -6.65 -0.34 1.14e-10 Pancreatic cancer; LIHC cis rs3736594 0.722 rs12993377 chr2:27952767 G/C cg27432699 chr2:27873401 GPN1 -0.46 -7.08 -0.36 8.29e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs3768617 0.745 rs4546885 chr1:183025555 C/G ch.1.3577855R chr1:183094577 LAMC1 0.49 7.94 0.39 2.88e-14 Fuchs's corneal dystrophy; LIHC cis rs7937890 0.587 rs11023204 chr11:14411223 C/A cg22961513 chr11:14280813 SPON1 -0.44 -6.63 -0.34 1.32e-10 Mitochondrial DNA levels; LIHC cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg18357526 chr6:26021779 HIST1H4A 0.6 8.49 0.42 6.45e-16 Blood metabolite levels; LIHC cis rs6952808 0.929 rs2280546 chr7:1976863 G/A cg21782813 chr7:2030301 MAD1L1 0.47 8.1 0.4 9.64e-15 Bipolar disorder and schizophrenia; LIHC cis rs4319547 0.656 rs7294559 chr12:122837564 C/A cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.09 -0.36 7.78e-12 Body mass index; LIHC cis rs7818688 0.697 rs78088250 chr8:95972718 G/A cg16049864 chr8:95962084 TP53INP1 0.57 6.33 0.32 7.64e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs8180040 0.681 rs9818382 chr3:47193034 C/T cg16586182 chr3:47516702 SCAP -0.48 -8.46 -0.42 7.82e-16 Colorectal cancer; LIHC cis rs611744 0.967 rs702805 chr8:109235929 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs12477438 0.520 rs13030961 chr2:99799520 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.24 24.31 0.8 1.54e-76 Chronic sinus infection; LIHC cis rs11190604 1.000 rs2489050 chr10:102350898 T/A cg07080220 chr10:102295463 HIF1AN 0.55 7.71 0.38 1.37e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs67311347 0.577 rs11129870 chr3:40260406 G/A cg00656387 chr3:40428638 ENTPD3 0.42 6.59 0.34 1.67e-10 Renal cell carcinoma; LIHC cis rs4919694 0.572 rs12262258 chr10:104900272 G/A cg04362960 chr10:104952993 NT5C2 0.81 7.14 0.36 5.64e-12 Arsenic metabolism; LIHC cis rs9807841 0.538 rs892086 chr19:10837677 C/T cg17710535 chr19:10819994 QTRT1 0.4 6.2 0.32 1.64e-9 Inflammatory skin disease; LIHC cis rs77741769 0.571 rs869781 chr12:121340246 T/C cg02419362 chr12:121203948 SPPL3 0.33 5.77 0.3 1.73e-8 Mean corpuscular volume; LIHC cis rs1003719 0.788 rs2835578 chr21:38457671 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.21 0.55 1.02e-28 Eye color traits; LIHC cis rs2645694 0.626 rs2703116 chr4:77824289 C/T cg03477792 chr4:77819574 ANKRD56 -0.58 -8.33 -0.41 1.92e-15 Emphysema distribution in smoking; LIHC cis rs10847980 0.590 rs1696326 chr12:123311981 A/G cg25930673 chr12:123319894 HIP1R -1.0 -11.02 -0.51 2.32e-24 Adiponectin levels; LIHC cis rs1046896 0.628 rs12452314 chr17:80723362 A/G cg02398342 chr17:80708632 TBCD;FN3K 0.54 8.36 0.41 1.63e-15 Glycated hemoglobin levels; LIHC cis rs9911578 0.835 rs9889419 chr17:56473259 C/T cg12560992 chr17:57184187 TRIM37 0.9 14.94 0.63 3.46e-39 Intelligence (multi-trait analysis); LIHC cis rs5753037 0.543 rs131284 chr22:30157589 T/C cg01021169 chr22:30184971 ASCC2 -0.33 -6.29 -0.32 9.81e-10 Type 1 diabetes; LIHC cis rs6121246 0.821 rs6121209 chr20:30311258 G/C cg13852791 chr20:30311386 BCL2L1 0.96 9.81 0.47 3.41e-20 Mean corpuscular hemoglobin; LIHC cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg21782813 chr7:2030301 MAD1L1 0.46 7.74 0.39 1.14e-13 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.895 rs12531677 chr7:65769086 G/A cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg07061783 chr6:25882402 NA -0.43 -6.05 -0.31 3.77e-9 Blood metabolite levels; LIHC cis rs12477438 0.520 rs2964969 chr2:99782811 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.2 0.61 2.65e-36 Chronic sinus infection; LIHC cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg09323728 chr8:95962352 TP53INP1 -0.3 -6.51 -0.33 2.68e-10 Type 2 diabetes; LIHC cis rs801193 1.000 rs2420824 chr7:66131116 G/A cg18876405 chr7:65276391 NA -0.41 -6.97 -0.35 1.65e-11 Aortic root size; LIHC cis rs7635838 0.617 rs347590 chr3:11289561 G/A cg00170343 chr3:11313890 ATG7 0.6 9.93 0.47 1.4e-20 HDL cholesterol; LIHC cis rs477895 0.713 rs12575642 chr11:63979643 G/T cg04317338 chr11:64019027 PLCB3 0.8 9.79 0.47 3.96e-20 Mean platelet volume; LIHC cis rs17685 0.884 rs3823882 chr7:75631913 T/C cg04592579 chr7:75616294 TMEM120A -0.35 -6.01 -0.31 4.79e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7208859 0.673 rs73277984 chr17:29196133 T/C cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs295140 0.506 rs4673854 chr2:201134736 G/A cg23649088 chr2:200775458 C2orf69 -0.49 -6.85 -0.35 3.53e-11 QT interval; LIHC cis rs769267 0.896 rs11882123 chr19:19386339 A/G cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs921968 0.541 rs3770216 chr2:219443717 A/G cg02985541 chr2:219472218 PLCD4 -0.42 -6.72 -0.34 7.85e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs6952808 0.760 rs11764960 chr7:1950532 G/A cg14004847 chr7:1930337 MAD1L1 -0.48 -6.82 -0.35 4.25e-11 Bipolar disorder and schizophrenia; LIHC trans rs728616 0.681 rs12769764 chr10:81917113 C/G cg12963312 chr6:52441723 TRAM2 0.43 6.3 0.32 9.28e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs9611519 0.780 rs9611527 chr22:41644428 G/A cg06634786 chr22:41940651 POLR3H -0.57 -6.8 -0.35 4.67e-11 Neuroticism; LIHC cis rs754466 0.724 rs11002318 chr10:79633807 G/A cg17075019 chr10:79541650 NA -0.75 -11.39 -0.52 1.11e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7106204 0.748 rs28656439 chr11:24207653 G/C ch.11.24196551F chr11:24239977 NA 0.76 10.02 0.48 6.77e-21 Response to Homoharringtonine (cytotoxicity); LIHC cis rs941408 0.963 rs2537855 chr19:2806574 A/G cg06609049 chr19:2785107 THOP1 0.55 9.67 0.46 1.05e-19 Total cholesterol levels; LIHC cis rs11048434 0.736 rs1805732 chr12:9090892 A/G cg04155231 chr12:9217510 LOC144571 -0.31 -6.01 -0.31 4.78e-9 Sjögren's syndrome; LIHC cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg13047869 chr3:10149882 C3orf24 0.55 6.93 0.35 2.08e-11 Alzheimer's disease; LIHC cis rs910316 1.000 rs8003506 chr14:75586288 A/C cg08847533 chr14:75593920 NEK9 -0.86 -18.03 -0.7 1.47e-51 Height; LIHC cis rs8114671 0.562 rs6058137 chr20:33475074 G/A cg07148914 chr20:33460835 GGT7 0.66 10.14 0.48 2.7e-21 Height; LIHC cis rs506338 0.517 rs1207179 chr11:64450795 C/T cg08800856 chr11:64428347 NRXN2 0.39 6.11 0.31 2.65e-9 Body mass index;Urate levels; LIHC cis rs7618501 0.521 rs952594 chr3:49908023 G/A cg21467203 chr3:49911342 NA -0.6 -10.96 -0.51 3.81e-24 Intelligence (multi-trait analysis); LIHC cis rs7238033 0.641 rs8086499 chr18:43321412 A/G cg20610511 chr18:43302872 SLC14A1 0.35 5.82 0.3 1.37e-8 Bladder cancer; LIHC cis rs716804 0.729 rs10840382 chr11:10298050 C/T cg01453529 chr11:10209919 SBF2 -0.29 -5.86 -0.3 1.11e-8 Neuroticism; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02520519 chr3:4345006 SETMAR -0.51 -6.81 -0.35 4.29e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3796352 0.667 rs3755805 chr3:52866299 G/A cg04865290 chr3:52927548 TMEM110 -0.45 -6.11 -0.31 2.65e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7552404 0.690 rs7549863 chr1:76327923 T/C cg03433033 chr1:76189801 ACADM -0.54 -6.87 -0.35 3.06e-11 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2262909 0.962 rs73019842 chr19:22249909 T/G cg05197062 chr11:11642011 GALNTL4 0.42 6.08 0.31 3.17e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2425143 1.000 rs57963833 chr20:34344225 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -6.92 -0.35 2.29e-11 Blood protein levels; LIHC cis rs2204008 0.744 rs1115514 chr12:38280140 C/T cg13010199 chr12:38710504 ALG10B 0.48 5.75 0.3 1.96e-8 Bladder cancer; LIHC cis rs9790314 0.846 rs4290817 chr3:160967354 G/A cg03342759 chr3:160939853 NMD3 -0.82 -13.51 -0.59 1.31e-33 Morning vs. evening chronotype; LIHC cis rs7772486 0.875 rs2814873 chr6:146308932 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.43 0.53 7.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 1.000 rs3981131 chr7:65951677 A/G cg18876405 chr7:65276391 NA 0.34 6.07 0.31 3.35e-9 Aortic root size; LIHC trans rs7618501 0.633 rs9814664 chr3:50078541 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.57 -9.34 -0.45 1.3e-18 Intelligence (multi-trait analysis); LIHC cis rs600806 0.821 rs10127790 chr1:109891133 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.21 -0.32 1.53e-9 Intelligence (multi-trait analysis); LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg05484376 chr2:27715224 FNDC4 0.37 6.41 0.33 4.8e-10 Total body bone mineral density; LIHC trans rs1005277 0.579 rs2505241 chr10:38442421 T/C cg17830980 chr10:43048298 ZNF37B -0.56 -11.46 -0.53 6.04e-26 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg11494091 chr17:61959527 GH2 -0.44 -8.16 -0.4 6.42e-15 Prudent dietary pattern; LIHC cis rs6546550 0.901 rs6729760 chr2:70161032 C/T cg02498382 chr2:70120550 SNRNP27 -0.41 -6.98 -0.35 1.54e-11 Prevalent atrial fibrillation; LIHC cis rs10876993 0.928 rs1678532 chr12:58055197 T/G cg18357645 chr12:58087776 OS9 0.52 8.5 0.42 5.89e-16 Celiac disease or Rheumatoid arthritis; LIHC trans rs2243480 0.522 rs431168 chr7:65511604 G/T cg10756647 chr7:56101905 PSPH 1.15 13.19 0.58 2.04e-32 Diabetic kidney disease; LIHC cis rs6456156 0.586 rs12528689 chr6:167461746 A/G cg23791538 chr6:167370224 RNASET2 -0.53 -8.64 -0.42 2.18e-16 Primary biliary cholangitis; LIHC cis rs6815814 0.950 rs55903115 chr4:38786474 C/A cg06935464 chr4:38784597 TLR10 0.55 8.98 0.44 1.91e-17 Breast cancer; LIHC cis rs77106637 0.858 rs7109575 chr11:72463435 G/A cg03713592 chr11:72463424 ARAP1 1.13 10.28 0.49 8.88e-22 Type 2 diabetes; LIHC trans rs2727020 0.576 rs1814175 chr11:49559172 T/C cg18944383 chr4:111397179 ENPEP 0.25 6.15 0.32 2.15e-9 Coronary artery disease; LIHC cis rs7552404 1.000 rs12091720 chr1:76186949 G/A cg22875332 chr1:76189707 ACADM 0.48 7.15 0.36 5.42e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6461049 0.800 rs2398706 chr7:2156338 A/T cg02951883 chr7:2050386 MAD1L1 -0.64 -10.42 -0.49 2.98e-22 Schizophrenia; LIHC cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -6.33 -0.32 7.81e-10 Bipolar disorder and schizophrenia; LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg21782813 chr7:2030301 MAD1L1 0.56 10.14 0.48 2.61e-21 Bipolar disorder and schizophrenia; LIHC cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg03517284 chr6:25882590 NA -0.64 -8.97 -0.44 1.95e-17 Blood metabolite levels; LIHC cis rs3617 0.522 rs6773650 chr3:52897095 A/T cg11645453 chr3:52864694 ITIH4 0.23 5.8 0.3 1.5e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs7651039 0.641 rs2455827 chr3:15662906 C/G cg16303742 chr3:15540471 COLQ 0.54 9.54 0.46 2.74e-19 Coronary heart disease; LIHC cis rs9916302 0.904 rs6503506 chr17:37524653 C/A cg00129232 chr17:37814104 STARD3 0.41 6.57 0.33 1.89e-10 Glomerular filtration rate (creatinine); LIHC cis rs8027181 0.804 rs7178130 chr15:72978202 A/G cg25996835 chr15:72978165 BBS4;HIGD2B -0.5 -7.79 -0.39 8.37e-14 Triglyceride levels; LIHC cis rs79387448 0.745 rs6709719 chr2:103144953 G/A cg09003973 chr2:102972529 NA 0.89 7.63 0.38 2.33e-13 Gut microbiota (bacterial taxa); LIHC trans rs6897795 0.680 rs10074768 chr5:177610700 A/G cg19598605 chr2:70056955 GMCL1 -0.6 -7.65 -0.38 2.05e-13 Plateletcrit; LIHC cis rs6750047 0.566 rs1157185 chr2:38285735 C/T cg07380506 chr2:38303506 CYP1B1 0.63 8.27 0.41 3.06e-15 Cutaneous malignant melanoma;Melanoma; LIHC cis rs354225 0.586 rs966003 chr2:54884870 C/T cg26097391 chr2:54893211 SPTBN1 0.39 6.04 0.31 3.92e-9 Schizophrenia; LIHC cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs4713118 0.513 rs202908 chr6:28011551 C/G cg23485639 chr6:28045615 ZNF165 0.39 6.0 0.31 5.11e-9 Parkinson's disease; LIHC cis rs9918079 0.506 rs10214 chr4:15606431 T/C cg21329975 chr4:15471214 CC2D2A 0.43 6.47 0.33 3.44e-10 Obesity-related traits; LIHC cis rs427394 0.582 rs274667 chr5:6710771 A/G cg10857441 chr5:6722123 POLS 0.38 6.38 0.33 5.68e-10 Menopause (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06438056 chr1:33502433 AK2 -0.49 -6.93 -0.35 2.06e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg06634786 chr22:41940651 POLR3H 0.82 8.92 0.43 2.96e-17 Vitiligo; LIHC cis rs9640161 0.742 rs11767726 chr7:150018096 A/C cg12556325 chr7:150026731 C7orf29;LRRC61 0.47 8.4 0.41 1.23e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs2075371 0.931 rs1646697 chr7:133999930 G/A cg20476274 chr7:133979776 SLC35B4 0.74 12.16 0.55 1.65e-28 Mean platelet volume; LIHC cis rs12477438 0.834 rs11903311 chr2:99701807 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.58 -8.24 -0.41 3.78e-15 Chronic sinus infection; LIHC cis rs727505 1.000 rs720614 chr7:124452790 T/C cg23710748 chr7:124431027 NA -0.34 -5.93 -0.31 7.46e-9 Lewy body disease; LIHC cis rs9649213 0.593 rs6961438 chr7:98005849 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.85 -0.3 1.15e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs4917300 0.605 rs1388800 chr8:143106264 C/T cg25363559 chr8:143086065 NA 0.25 7.84 0.39 5.95e-14 Amyotrophic lateral sclerosis; LIHC cis rs36051895 0.626 rs12349785 chr9:5076613 G/C cg02405213 chr9:5042618 JAK2 -0.68 -11.62 -0.53 1.54e-26 Pediatric autoimmune diseases; LIHC cis rs6960043 0.846 rs7781710 chr7:15056045 T/A cg19272540 chr7:15055459 NA 0.25 6.93 0.35 2.08e-11 Type 2 diabetes; LIHC cis rs7772486 0.686 rs702305 chr6:145973840 A/G cg23711669 chr6:146136114 FBXO30 -0.67 -12.11 -0.55 2.54e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs6684514 1.000 rs12040868 chr1:156284803 G/T cg16558208 chr1:156270281 VHLL 0.55 10.36 0.49 4.85e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs763121 0.853 rs926299 chr22:39095698 C/G cg06022373 chr22:39101656 GTPBP1 0.74 14.71 0.62 2.82e-38 Menopause (age at onset); LIHC cis rs6500602 0.627 rs863501 chr16:4588394 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.45 -6.43 -0.33 4.2e-10 Schizophrenia; LIHC trans rs2727020 0.553 rs11040400 chr11:49518296 C/A cg18944383 chr4:111397179 ENPEP 0.26 6.37 0.33 6.14e-10 Coronary artery disease; LIHC cis rs6662572 0.806 rs11211133 chr1:45991079 G/A cg03123370 chr1:45965343 CCDC163P;MMACHC 0.57 5.93 0.31 7.33e-9 Blood protein levels; LIHC cis rs5769765 0.862 rs56377703 chr22:50306940 C/T cg02269571 chr22:50332266 NA -0.76 -10.08 -0.48 4.45e-21 Schizophrenia; LIHC cis rs79057730 0.528 rs4719313 chr7:822501 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.81 8.88 0.43 3.93e-17 Initial pursuit acceleration; LIHC trans rs561341 0.882 rs16967101 chr17:30377162 A/G cg20587970 chr11:113659929 NA -1.08 -10.08 -0.48 4.39e-21 Hip circumference adjusted for BMI; LIHC trans rs1920116 0.744 rs9833035 chr3:169553498 G/T cg00669760 chr2:44735195 C2orf34 0.38 6.11 0.31 2.79e-9 Glioma (high-grade); LIHC cis rs709400 1.000 rs61995780 chr14:104120612 A/G cg26031613 chr14:104095156 KLC1 1.06 14.27 0.61 1.48e-36 Body mass index; LIHC cis rs6840360 0.571 rs17275598 chr4:152568478 C/A cg22705602 chr4:152727874 NA -0.36 -6.87 -0.35 3.1e-11 Intelligence (multi-trait analysis); LIHC cis rs7188861 1.000 rs889648 chr16:11455816 G/C cg01510278 chr16:11456238 NA 0.48 5.71 0.3 2.44e-8 HDL cholesterol; LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg18306943 chr3:40428807 ENTPD3 0.42 7.44 0.37 8.23e-13 Renal cell carcinoma; LIHC cis rs17685 0.753 rs10476 chr7:75696420 C/T cg04592579 chr7:75616294 TMEM120A -0.39 -6.83 -0.35 3.98e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9581857 0.685 rs9319371 chr13:28042564 A/G cg22138327 chr13:27999177 GTF3A 0.76 6.26 0.32 1.17e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg08392591 chr16:89556376 ANKRD11 0.4 6.02 0.31 4.55e-9 Multiple myeloma (IgH translocation); LIHC cis rs2991971 0.810 rs2356413 chr1:45914048 A/T cg24296786 chr1:45957014 TESK2 -0.54 -8.34 -0.41 1.88e-15 High light scatter reticulocyte count; LIHC cis rs6754311 0.608 rs3739020 chr2:136602491 T/G cg07305463 chr2:136567211 LCT -0.33 -6.13 -0.31 2.41e-9 Mosquito bite size; LIHC cis rs7246657 0.943 rs10409204 chr19:37917692 G/A cg23950597 chr19:37808831 NA -0.49 -6.31 -0.32 8.8e-10 Coronary artery calcification; LIHC cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg22168489 chr12:122356033 WDR66 0.46 6.43 0.33 4.3e-10 Mean corpuscular volume; LIHC cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.78 11.86 0.54 2.11e-27 Total body bone mineral density; LIHC cis rs1348850 0.519 rs1544002 chr2:178529534 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.59 7.77 0.39 8.97e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1865721 0.804 rs59187673 chr18:73143964 A/G cg26385618 chr18:73139727 C18orf62 -0.31 -8.01 -0.4 1.85e-14 Intelligence; LIHC cis rs1691799 0.899 rs1185244 chr12:66725160 C/T cg16791601 chr12:66731901 HELB -0.56 -13.68 -0.59 2.88e-34 White blood cell count (basophil); LIHC cis rs1355223 0.902 rs34875830 chr11:34722205 T/C cg11058730 chr11:34937778 PDHX;APIP -0.47 -6.58 -0.34 1.75e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs916888 0.779 rs199528 chr17:44843136 C/T cg01570182 chr17:44337453 NA 1.0 9.71 0.46 7.65e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg26338869 chr17:61819248 STRADA 0.59 8.7 0.43 1.42e-16 Prudent dietary pattern; LIHC cis rs9733 0.596 rs1336898 chr1:150665050 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.3 0.32 9.39e-10 Tonsillectomy; LIHC cis rs888194 0.686 rs11067376 chr12:110027795 A/G cg05360138 chr12:110035743 NA 0.46 6.03 0.31 4.31e-9 Neuroticism; LIHC cis rs798554 0.757 rs1182188 chr7:2869985 T/C cg04166393 chr7:2884313 GNA12 0.44 5.8 0.3 1.54e-8 Height; LIHC cis rs826838 1.000 rs826891 chr12:39100824 A/G cg13010199 chr12:38710504 ALG10B -0.39 -5.83 -0.3 1.28e-8 Heart rate; LIHC cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.48 0.53 5.1e-26 Alzheimer's disease; LIHC cis rs903552 1.000 rs12904206 chr15:102006294 C/T cg19295451 chr15:102010161 PCSK6 -0.44 -6.12 -0.31 2.6e-9 Diabetic kidney disease; LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg21003380 chr1:156261207 TMEM79 0.37 5.92 0.31 7.71e-9 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs11958404 0.517 rs17679725 chr5:157221489 A/G cg05962755 chr5:157440814 NA 0.67 6.76 0.34 5.96e-11 IgG glycosylation; LIHC cis rs7937682 0.960 rs480293 chr11:111469132 A/C cg09085632 chr11:111637200 PPP2R1B -0.92 -11.29 -0.52 2.47e-25 Primary sclerosing cholangitis; LIHC cis rs12980942 0.872 rs12974420 chr19:41798660 A/G cg25627403 chr19:41769009 HNRNPUL1 0.58 7.08 0.36 8.42e-12 Coronary artery disease; LIHC cis rs11122272 0.735 rs2572248 chr1:231514942 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs72634258 0.503 rs707457 chr1:7831064 C/A cg26816564 chr1:7831052 VAMP3 0.69 6.44 0.33 3.97e-10 Inflammatory bowel disease; LIHC cis rs6442522 0.678 rs3773452 chr3:15509954 C/A cg16303742 chr3:15540471 COLQ 0.47 7.85 0.39 5.45e-14 Uric acid levels; LIHC trans rs1814175 0.588 rs1721994 chr11:49914050 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC trans rs17685 0.632 rs1859793 chr7:75821283 G/A cg19862616 chr7:65841803 NCRNA00174 0.74 13.56 0.59 8.11e-34 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2439831 0.867 rs6493085 chr15:43654182 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC cis rs4304924 0.500 rs7339081 chr13:79235501 A/G cg01819759 chr13:79234251 RNF219 0.56 7.1 0.36 7.43e-12 Large artery stroke; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg10660865 chr9:128024595 GAPVD1 0.46 6.65 0.34 1.16e-10 Morning vs. evening chronotype; LIHC cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg01448562 chr3:133502909 NA 0.42 6.78 0.34 5.45e-11 Iron status biomarkers; LIHC trans rs9388451 0.874 rs9398787 chr6:126090608 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.55 -8.82 -0.43 5.91e-17 Brugada syndrome; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs7582180 0.764 rs10180423 chr2:100919012 C/G cg14675211 chr2:100938903 LONRF2 0.53 8.1 0.4 9.82e-15 Intelligence (multi-trait analysis); LIHC cis rs9628987 0.612 rs6684863 chr1:8426236 G/A cg20416874 chr1:8611966 RERE 0.49 5.96 0.31 6.22e-9 Breast cancer; LIHC cis rs6977660 0.714 rs12537283 chr7:19817658 G/T cg07541023 chr7:19748670 TWISTNB 0.4 5.88 0.3 9.55e-9 Thyroid stimulating hormone; LIHC cis rs7131987 0.617 rs3764953 chr12:29502236 T/C cg16970926 chr12:29381810 FAR2 0.29 5.91 0.3 8.14e-9 QT interval; LIHC trans rs9929218 0.817 rs8055912 chr16:68802068 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -8.67 -0.42 1.83e-16 Colorectal cancer; LIHC cis rs72627509 0.680 rs66790703 chr4:57773908 G/A cg26694713 chr4:57773883 REST 0.73 10.52 0.49 1.34e-22 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg07414643 chr4:187882934 NA 0.23 5.72 0.3 2.31e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs317689 0.690 rs547827 chr12:69669703 G/A cg19645103 chr12:69753606 YEATS4 -0.44 -5.97 -0.31 5.96e-9 Response to diuretic therapy; LIHC cis rs892961 0.867 rs6501955 chr17:75414443 A/G cg01320579 chr17:75405842 SEPT9 0.52 7.44 0.37 8.37e-13 Airflow obstruction; LIHC cis rs9640161 0.742 rs11767726 chr7:150018096 A/C cg21361702 chr7:150065534 REPIN1 -0.45 -6.32 -0.32 8.35e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs7617773 0.817 rs3731534 chr3:48211777 C/T cg11946769 chr3:48343235 NME6 0.89 11.16 0.52 7.38e-25 Coronary artery disease; LIHC cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg00149659 chr3:10157352 C3orf10 0.65 6.97 0.35 1.63e-11 Alzheimer's disease; LIHC cis rs11098499 0.863 rs3775845 chr4:120432447 T/C cg09307838 chr4:120376055 NA 0.77 11.95 0.54 9.51e-28 Corneal astigmatism; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg20295408 chr7:1910781 MAD1L1 0.47 6.95 0.35 1.89e-11 Bipolar disorder and schizophrenia; LIHC cis rs28830936 0.510 rs11070349 chr15:42085017 A/C cg17847044 chr15:42102381 MAPKBP1 -0.48 -11.61 -0.53 1.74e-26 Diastolic blood pressure; LIHC cis rs992157 0.735 rs2271541 chr2:219082119 G/T cg20019365 chr2:219134978 PNKD;AAMP 0.79 13.36 0.59 4.59e-33 Colorectal cancer; LIHC cis rs6582630 0.502 rs3902522 chr12:38271203 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.52 0.49 1.35e-22 Drug-induced liver injury (flucloxacillin); LIHC cis rs7945705 0.902 rs10743095 chr11:8936984 T/C cg12365402 chr11:9010492 NRIP3 0.3 7.88 0.39 4.54e-14 Hemoglobin concentration; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg22903471 chr2:27725779 GCKR -0.46 -7.92 -0.39 3.38e-14 Total body bone mineral density; LIHC cis rs9420 0.528 rs73480556 chr11:57400462 G/C cg19752551 chr11:57585705 CTNND1 -0.46 -5.88 -0.3 9.75e-9 Schizophrenia; LIHC cis rs6598955 0.614 rs1134584 chr1:26608828 G/A cg00852783 chr1:26633632 UBXN11 0.48 7.85 0.39 5.47e-14 Obesity-related traits; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg23131131 chr22:24373011 LOC391322 -0.64 -9.07 -0.44 9.61e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs35160687 0.623 rs11689971 chr2:86474471 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.39 6.31 0.32 8.7e-10 Night sleep phenotypes; LIHC cis rs2075371 0.829 rs35897155 chr7:134002711 G/A cg20476274 chr7:133979776 SLC35B4 0.68 9.38 0.45 9.41e-19 Mean platelet volume; LIHC cis rs6570726 0.935 rs453609 chr6:145812332 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.82 0.47 3.32e-20 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23651808 chr4:8200974 SH3TC1 0.47 6.16 0.32 2.1e-9 Lung function (FEV1/FVC); LIHC cis rs8114671 0.836 rs6142284 chr20:33641367 G/A cg07148914 chr20:33460835 GGT7 -0.56 -8.51 -0.42 5.67e-16 Height; LIHC cis rs8141529 0.719 rs9625619 chr22:29272328 T/A cg02153584 chr22:29168773 CCDC117 0.53 8.33 0.41 1.92e-15 Lymphocyte counts; LIHC cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.79 0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs10193935 0.901 rs10170082 chr2:42623452 T/C cg27598129 chr2:42591480 NA -0.68 -10.74 -0.5 2.2e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs7250872 0.647 rs12976128 chr19:1817113 A/C cg18850929 chr19:1828978 REXO1 0.39 6.39 0.33 5.51e-10 Bipolar disorder; LIHC cis rs10504229 0.679 rs16921606 chr8:58034477 A/C cg20607798 chr8:58055168 NA 0.41 5.98 0.31 5.63e-9 Developmental language disorder (linguistic errors); LIHC cis rs1256061 0.603 rs1152579 chr14:64695087 A/G cg23250157 chr14:64679961 SYNE2 0.43 6.29 0.32 9.9e-10 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs2070488 0.930 rs928813 chr3:38528537 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.95 0.65 3.35e-43 Electrocardiographic conduction measures; LIHC cis rs35883536 0.967 rs4908091 chr1:101138171 G/A cg14515779 chr1:101123966 NA -0.67 -13.3 -0.58 8.12e-33 Monocyte count; LIHC cis rs4891159 0.757 rs11665518 chr18:74147054 C/T cg24786174 chr18:74118243 ZNF516 -0.72 -12.96 -0.57 1.62e-31 Longevity; LIHC cis rs2273669 0.588 rs111353760 chr6:109306493 T/G cg05315195 chr6:109294784 ARMC2 -0.52 -5.76 -0.3 1.88e-8 Prostate cancer; LIHC trans rs72960926 0.744 rs952120 chr6:74917250 T/G cg07247405 chr1:2484626 LOC115110 0.52 6.19 0.32 1.75e-9 Metabolite levels (MHPG); LIHC cis rs7772486 0.686 rs9399564 chr6:146078907 C/T cg13319975 chr6:146136371 FBXO30 0.35 5.8 0.3 1.52e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6963495 0.769 rs11556986 chr7:105177041 A/T cg19920283 chr7:105172520 RINT1 0.66 6.35 0.32 6.89e-10 Bipolar disorder (body mass index interaction); LIHC cis rs5758511 0.514 rs5751221 chr22:42516366 C/T cg00645731 chr22:42541494 CYP2D7P1 0.52 8.37 0.41 1.49e-15 Birth weight; LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.64 -9.14 -0.44 5.8e-18 Lymphocyte counts; LIHC cis rs16854884 0.586 rs2011080 chr3:143756149 T/G cg06585982 chr3:143692056 C3orf58 0.6 7.82 0.39 6.51e-14 Economic and political preferences (feminism/equality); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01999652 chr6:28220110 ZKSCAN4 0.52 7.27 0.37 2.48e-12 Pancreatic cancer; LIHC cis rs8067354 0.830 rs2453913 chr17:57860150 G/T cg02344993 chr17:57696989 CLTC 0.53 8.5 0.42 6.08e-16 Hemoglobin concentration; LIHC cis rs7100689 0.622 rs1890890 chr10:82090643 A/T cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs2072499 0.898 rs2758609 chr1:156202868 G/A cg24450063 chr1:156163899 SLC25A44 0.71 11.81 0.54 3.09e-27 Testicular germ cell tumor; LIHC cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg22800045 chr5:56110881 MAP3K1 0.69 8.8 0.43 6.79e-17 Initial pursuit acceleration; LIHC cis rs9596863 1.000 rs9596855 chr13:54407032 G/A ch.13.53330881F chr13:54432880 NA 0.44 5.98 0.31 5.48e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs6754311 0.731 rs1470457 chr2:136581848 A/G cg07169764 chr2:136633963 MCM6 0.8 12.54 0.56 6.13e-30 Mosquito bite size; LIHC cis rs3096299 0.933 rs889576 chr16:89429653 A/G cg01788221 chr16:89496183 ANKRD11 0.39 6.14 0.32 2.31e-9 Multiple myeloma (IgH translocation); LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg09033563 chr22:24373618 LOC391322 -0.52 -7.25 -0.37 2.78e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg04025307 chr7:1156635 C7orf50 0.65 11.23 0.52 3.92e-25 Longevity;Endometriosis; LIHC cis rs6582630 0.537 rs6582500 chr12:38534206 G/A cg13010199 chr12:38710504 ALG10B 0.55 6.54 0.33 2.27e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg12516959 chr21:47718080 NA -0.36 -5.8 -0.3 1.51e-8 Testicular germ cell tumor; LIHC cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg09417038 chr21:47716443 C21orf57 -0.49 -7.48 -0.37 6.46e-13 Testicular germ cell tumor; LIHC cis rs3020736 0.500 rs4147641 chr22:42482502 C/G cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs7584330 0.737 rs1497128 chr2:238369211 A/G cg14458575 chr2:238380390 NA 0.38 5.85 0.3 1.13e-8 Prostate cancer; LIHC cis rs7582180 0.627 rs4407265 chr2:101005846 C/G cg14675211 chr2:100938903 LONRF2 0.56 8.27 0.41 3.07e-15 Intelligence (multi-trait analysis); LIHC cis rs710865 0.516 rs12062540 chr1:19529204 A/G cg13387374 chr1:19411106 UBR4 0.41 6.77 0.34 5.52e-11 Brain structure; LIHC cis rs2235642 0.750 rs2859310 chr16:1656765 C/T cg09025071 chr16:1593152 IFT140;TMEM204 -0.29 -5.74 -0.3 2.14e-8 Coronary artery disease; LIHC cis rs11724804 0.532 rs62297079 chr4:879977 G/A cg08222618 chr4:941054 TMEM175 0.57 8.3 0.41 2.49e-15 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs17021463 0.643 rs6841656 chr4:95300532 A/G cg11021082 chr4:95130006 SMARCAD1 0.42 7.08 0.36 8.2e-12 Testicular germ cell tumor; LIHC cis rs79149102 0.850 rs78646589 chr15:75170580 C/T cg16226627 chr15:75307476 SCAMP5 0.45 6.31 0.32 8.67e-10 Lung cancer; LIHC cis rs1018836 0.812 rs10808619 chr8:91622916 A/T cg16814680 chr8:91681699 NA -0.61 -9.83 -0.47 2.93e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10791323 0.604 rs2723607 chr11:133711018 C/G cg06766960 chr11:133703094 NA -0.67 -11.15 -0.52 7.7e-25 Childhood ear infection; LIHC cis rs10540 1.000 rs61876339 chr11:495283 T/C cg03352830 chr11:487213 PTDSS2 0.85 7.17 0.36 4.77e-12 Body mass index; LIHC trans rs7120489 0.541 rs11022352 chr11:12444804 T/C cg08537300 chr5:179058959 NA 0.58 6.28 0.32 1.03e-9 Mortality in heart failure; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg00280220 chr17:61926910 NA 0.42 6.5 0.33 2.82e-10 Prudent dietary pattern; LIHC trans rs6598955 0.671 rs11247910 chr1:26645666 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.71 -7.22 -0.36 3.46e-12 Obesity-related traits; LIHC cis rs8062405 0.755 rs17640009 chr16:28595700 A/G cg07451762 chr16:28383216 NA 0.39 6.93 0.35 2.05e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7208859 0.673 rs61348930 chr17:29221763 C/T cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67478160 0.634 rs7141928 chr14:104219949 C/T cg08213375 chr14:104286397 PPP1R13B 0.53 10.13 0.48 3.01e-21 Schizophrenia; LIHC cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg20295408 chr7:1910781 MAD1L1 -0.48 -6.82 -0.35 4.21e-11 Bipolar disorder and schizophrenia; LIHC cis rs56104184 0.775 rs73061689 chr19:49397214 C/T cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7727544 0.684 rs272869 chr5:131677997 A/G cg07395648 chr5:131743802 NA -0.29 -6.07 -0.31 3.48e-9 Blood metabolite levels; LIHC cis rs780096 0.546 rs2293571 chr2:27729480 C/T cg22903471 chr2:27725779 GCKR -0.51 -8.86 -0.43 4.3e-17 Total body bone mineral density; LIHC trans rs79976124 0.879 rs17432710 chr6:66621744 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.67 0.34 1.04e-10 Type 2 diabetes; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20864579 chr11:76813988 OMP;CAPN5 0.42 6.17 0.32 1.98e-9 Longevity; LIHC cis rs34779708 0.733 rs4934740 chr10:35547141 C/T cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2224391 1.000 rs2753249 chr6:5263475 T/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs6754311 0.509 rs3820794 chr2:136505546 C/T cg07169764 chr2:136633963 MCM6 -0.78 -11.82 -0.54 2.82e-27 Mosquito bite size; LIHC cis rs7937682 0.575 rs10789851 chr11:111750955 G/C cg09085632 chr11:111637200 PPP2R1B 0.96 13.91 0.6 3.63e-35 Primary sclerosing cholangitis; LIHC cis rs12824058 0.831 rs12314111 chr12:130813663 G/T cg24838063 chr12:130822603 PIWIL1 0.66 9.78 0.47 4.5e-20 Menopause (age at onset); LIHC cis rs2204008 0.837 rs12370891 chr12:37984531 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs5758511 0.680 rs5758657 chr22:42618669 A/G cg20195005 chr22:42527684 CYP2D6 0.31 5.9 0.3 8.56e-9 Birth weight; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg26668828 chr6:292823 DUSP22 -0.67 -9.61 -0.46 1.69e-19 Menopause (age at onset); LIHC cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg06212747 chr3:49208901 KLHDC8B 0.67 9.15 0.44 5.2e-18 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg22528358 chr1:107598549 PRMT6 -0.69 -11.54 -0.53 3e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11098499 0.779 rs10011097 chr4:120310359 T/G cg09307838 chr4:120376055 NA 0.76 11.8 0.54 3.51e-27 Corneal astigmatism; LIHC cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.53 0.33 2.32e-10 Bipolar disorder; LIHC cis rs4853525 0.522 rs6434412 chr2:191585275 A/G cg05765582 chr2:191677683 NA 0.3 5.79 0.3 1.63e-8 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC trans rs9858542 1.000 rs9822268 chr3:49719729 G/A cg21659725 chr3:3221576 CRBN -0.55 -6.17 -0.32 1.94e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg13393036 chr8:95962371 TP53INP1 -0.37 -8.62 -0.42 2.47e-16 Type 2 diabetes; LIHC cis rs9788682 1.000 rs9788682 chr15:78802586 A/G cg06917634 chr15:78832804 PSMA4 0.5 6.31 0.32 8.62e-10 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.65 0.38 2.01e-13 Prudent dietary pattern; LIHC trans rs7395662 0.571 rs4881998 chr11:48525186 C/T cg15704280 chr7:45808275 SEPT13 -0.45 -6.81 -0.35 4.36e-11 HDL cholesterol; LIHC cis rs8083850 0.698 rs4940251 chr18:50833082 A/C cg24270629 chr18:50823537 DCC -0.54 -8.36 -0.41 1.61e-15 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.97 0.8 4.54e-79 Prudent dietary pattern; LIHC cis rs9399135 0.967 rs2327580 chr6:135364417 A/C cg22676075 chr6:135203613 NA 0.41 6.59 0.34 1.66e-10 Red blood cell count; LIHC cis rs9457247 0.765 rs10455982 chr6:167448728 C/T cg07741184 chr6:167504864 NA 0.32 7.15 0.36 5.36e-12 Crohn's disease; LIHC cis rs10791097 0.748 rs4937580 chr11:130734270 T/C cg14779329 chr11:130786720 SNX19 0.4 6.15 0.32 2.11e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs2749592 0.513 rs1208708 chr10:38085576 A/G cg23533926 chr12:111358616 MYL2 -0.33 -6.6 -0.34 1.53e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7296418 0.663 rs11057276 chr12:123820397 C/T cg05973401 chr12:123451056 ABCB9 -0.4 -6.19 -0.32 1.73e-9 Platelet count; LIHC cis rs12971120 1.000 rs734559 chr18:72179579 G/A cg26446133 chr18:72167187 CNDP2 -0.79 -14.71 -0.62 2.74e-38 Refractive error; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.54 7.72 0.39 1.29e-13 Lymphocyte counts; LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg27170947 chr2:26402098 FAM59B -0.72 -8.69 -0.43 1.48e-16 Gut microbiome composition (summer); LIHC cis rs7312933 0.558 rs11181507 chr12:42844763 T/A cg17420585 chr12:42539391 GXYLT1 -0.35 -5.74 -0.3 2.07e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg08219700 chr8:58056026 NA 0.54 7.21 0.36 3.64e-12 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.966 rs4934730 chr10:35415555 A/G cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10508774 1.000 rs12251052 chr10:32746625 T/C cg01819863 chr10:32635814 EPC1 0.65 6.1 0.31 2.87e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2727020 0.734 rs1164664 chr11:49295542 T/G cg18944383 chr4:111397179 ENPEP -0.31 -6.93 -0.35 2.04e-11 Coronary artery disease; LIHC cis rs523522 0.962 rs2235218 chr12:120888619 A/C cg27279351 chr12:120934652 DYNLL1 0.65 11.49 0.53 4.61e-26 High light scatter reticulocyte count; LIHC trans rs7142002 1.000 rs12588314 chr14:102363857 G/A cg18984499 chr17:8286166 RPL26 0.65 6.19 0.32 1.77e-9 Autism; LIHC cis rs8180040 0.966 rs7649234 chr3:47494380 G/C cg16586182 chr3:47516702 SCAP -0.58 -11.29 -0.52 2.44e-25 Colorectal cancer; LIHC cis rs3764618 1.000 rs3764619 chr19:49497277 G/A cg14640682 chr19:49496473 GYS1;RUVBL2 -0.71 -5.81 -0.3 1.41e-8 Follicule stimulating hormone; LIHC cis rs2153535 0.580 rs6597337 chr6:8531652 C/T cg21535247 chr6:8435926 SLC35B3 0.65 8.6 0.42 2.93e-16 Motion sickness; LIHC cis rs506338 0.517 rs516117 chr11:64433444 T/C cg08800856 chr11:64428347 NRXN2 0.39 6.12 0.31 2.52e-9 Body mass index;Urate levels; LIHC trans rs1814175 0.645 rs7119101 chr11:49955665 G/A cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs7927771 0.697 rs11039307 chr11:47611152 C/T cg20135002 chr11:47629003 NA -0.53 -9.22 -0.45 3.08e-18 Subjective well-being; LIHC cis rs243505 0.528 rs740951 chr7:148470160 C/A cg09806900 chr7:148480153 CUL1 0.43 6.49 0.33 2.93e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs644799 0.562 rs654345 chr11:95581865 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.6 8.61 0.42 2.78e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2370759 1.000 rs79487858 chr10:32616405 T/C cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs4908768 0.501 rs1024197 chr1:8537058 C/G cg20416874 chr1:8611966 RERE -0.66 -13.83 -0.6 7.4e-35 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs796364 0.806 rs74771155 chr2:200913743 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs3768617 0.510 rs12078729 chr1:183060072 T/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.88 0.51 7.29e-24 Fuchs's corneal dystrophy; LIHC cis rs13631 0.697 rs1018330 chr9:139980385 A/C cg14289826 chr9:140003911 NA 0.35 5.84 0.3 1.23e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs6964587 1.000 rs7806184 chr7:91601978 A/G cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1e-57 Breast cancer; LIHC cis rs801193 1.000 rs62466793 chr7:66191517 G/A cg11764359 chr7:65958608 NA 0.71 10.55 0.5 1.04e-22 Aortic root size; LIHC cis rs11792861 0.816 rs28361111 chr9:111761012 A/C cg05043794 chr9:111880884 C9orf5 -0.31 -7.15 -0.36 5.34e-12 Menarche (age at onset); LIHC trans rs3749237 0.964 rs2234385 chr3:49846041 G/A cg21659725 chr3:3221576 CRBN 0.78 12.12 0.55 2.34e-28 Resting heart rate; LIHC cis rs10791097 0.720 rs7119425 chr11:130733185 C/T cg12179176 chr11:130786555 SNX19 0.79 12.8 0.57 6.41e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs743757 0.938 rs2236959 chr3:50441627 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.51 7.97 0.4 2.47e-14 Diastolic blood pressure; LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg23601095 chr6:26197514 HIST1H3D 0.55 5.83 0.3 1.27e-8 Gout;Renal underexcretion gout; LIHC trans rs208520 0.706 rs851601 chr6:66893853 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.32 -0.41 2.07e-15 Exhaled nitric oxide output; LIHC trans rs2073499 0.935 rs2526400 chr3:50186948 A/G cg21659725 chr3:3221576 CRBN -0.66 -7.35 -0.37 1.43e-12 Schizophrenia; LIHC cis rs894734 0.535 rs2366144 chr12:54324069 G/T cg25024717 chr12:54324583 NA -0.38 -8.01 -0.4 1.79e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs72949976 0.934 rs1922794 chr2:214026181 G/A cg08319019 chr2:214017104 IKZF2 -0.63 -6.74 -0.34 6.64e-11 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs4474465 1.000 rs4945281 chr11:78188627 C/G cg27205649 chr11:78285834 NARS2 -0.39 -6.0 -0.31 4.89e-9 Alzheimer's disease (survival time); LIHC cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg12756686 chr19:29218302 NA 0.44 6.79 0.34 4.88e-11 Methadone dose in opioid dependence; LIHC cis rs7903847 0.646 rs10882924 chr10:99159304 T/A cg06359132 chr10:99160096 RRP12 -0.41 -6.41 -0.33 4.83e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2841277 0.676 rs10438247 chr14:105411781 G/A cg21017887 chr14:105400489 NA 0.67 12.72 0.57 1.31e-30 Rheumatoid arthritis; LIHC cis rs2380220 0.606 rs7747776 chr6:96005852 C/T cg23517279 chr6:96025343 MANEA 0.55 6.41 0.33 4.8e-10 Behavioural disinhibition (generation interaction); LIHC cis rs11212260 0.655 rs11212222 chr11:107293442 A/G cg25435332 chr11:107328525 CWF19L2 0.79 8.09 0.4 1.08e-14 IgG glycosylation; LIHC cis rs950776 0.518 rs56007453 chr15:78826239 T/C cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs3806843 0.966 rs2563262 chr5:140137712 C/G cg26395211 chr5:140044315 WDR55 0.4 5.89 0.3 9.36e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs1814175 0.585 rs4881661 chr11:50000117 A/G cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs10870270 0.917 rs9971362 chr10:133790150 T/C cg26149184 chr10:133730230 NA 0.48 7.57 0.38 3.46e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg21448741 chr8:58168803 NA 0.36 5.91 0.3 8.43e-9 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.754 rs9390358 chr6:146145678 C/T cg05347473 chr6:146136440 FBXO30 0.37 6.11 0.31 2.73e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs17095355 1.000 rs57440982 chr10:111735772 G/A cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.84 -0.3 1.2e-8 Biliary atresia; LIHC cis rs4808199 0.649 rs34755166 chr19:19665581 G/A cg03709012 chr19:19516395 GATAD2A 0.98 13.15 0.58 2.91e-32 Nonalcoholic fatty liver disease; LIHC cis rs16958440 1.000 rs62096478 chr18:44662409 A/G cg17192377 chr18:44677553 HDHD2 0.6 6.71 0.34 8.24e-11 Sitting height ratio; LIHC cis rs66887589 0.616 rs11732621 chr4:120212883 A/C cg09307838 chr4:120376055 NA 0.55 8.18 0.4 5.66e-15 Diastolic blood pressure; LIHC cis rs11626933 1.000 rs7149083 chr14:90754006 G/A cg07150772 chr14:90864620 CALM1 -0.41 -5.83 -0.3 1.29e-8 Gut microbiota (bacterial taxa); LIHC cis rs9790314 0.902 rs9863590 chr3:161116445 T/C cg03342759 chr3:160939853 NMD3 -0.69 -8.11 -0.4 8.87e-15 Morning vs. evening chronotype; LIHC cis rs2204008 0.715 rs11495369 chr12:38238673 T/C cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs12936587 0.536 rs8075153 chr17:17622666 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.42 -6.85 -0.35 3.35e-11 Hip circumference;Coronary artery disease or large artery stroke;Coronary heart disease;Coronary artery disease; LIHC cis rs11098499 0.863 rs59732491 chr4:120489588 G/C cg09307838 chr4:120376055 NA 0.75 11.85 0.54 2.2e-27 Corneal astigmatism; LIHC cis rs7635838 0.892 rs6442252 chr3:11451416 T/C cg00170343 chr3:11313890 ATG7 0.42 6.57 0.33 1.83e-10 HDL cholesterol; LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg24693881 chr1:107596107 NA 0.52 9.02 0.44 1.39e-17 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3749237 0.964 rs13084243 chr3:49821878 G/C cg03060546 chr3:49711283 APEH 0.39 6.04 0.31 3.95e-9 Resting heart rate; LIHC cis rs6938 0.534 rs12904897 chr15:75217686 A/G cg14664628 chr15:75095509 CSK -0.47 -6.61 -0.34 1.47e-10 Breast cancer; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg22528358 chr1:107598549 PRMT6 0.72 11.91 0.54 1.33e-27 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs11098499 0.754 rs1849457 chr4:120254355 A/G cg25214090 chr10:38739885 LOC399744 0.52 8.42 0.41 1.06e-15 Corneal astigmatism; LIHC cis rs2404602 0.608 rs12911035 chr15:76606591 T/C cg22467129 chr15:76604101 ETFA -0.38 -6.16 -0.32 2.01e-9 Blood metabolite levels; LIHC cis rs6089829 0.962 rs6122350 chr20:61664617 A/G cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs1005277 0.579 rs1780115 chr10:38524773 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs17376456 0.877 rs10055741 chr5:93297187 C/T cg25358565 chr5:93447407 FAM172A 1.09 10.02 0.48 6.77e-21 Diabetic retinopathy; LIHC cis rs4803468 0.901 rs3745292 chr19:41888506 A/G cg09537434 chr19:41945824 ATP5SL -1.0 -20.43 -0.74 3.49e-61 Height; LIHC cis rs12887734 0.569 rs66953418 chr14:104271470 G/A cg08213375 chr14:104286397 PPP1R13B 0.54 9.41 0.45 7.71e-19 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs7103648 0.864 rs10769264 chr11:47423340 C/T cg20307385 chr11:47447363 PSMC3 1.03 18.23 0.7 2.34e-52 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs10089 1.000 rs6887847 chr5:127473807 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.74 0.34 6.56e-11 Ileal carcinoids; LIHC cis rs8014204 0.753 rs6574199 chr14:75356103 T/C cg08847533 chr14:75593920 NEK9 -0.38 -6.42 -0.33 4.53e-10 Caffeine consumption; LIHC cis rs600806 0.676 rs2781553 chr1:110026989 G/T cg11161837 chr1:110010384 SYPL2 -0.43 -5.78 -0.3 1.65e-8 Intelligence (multi-trait analysis); LIHC trans rs2096176 0.632 rs1915478 chr10:26330218 T/G cg01396774 chr2:218299024 DIRC3 -0.31 -6.12 -0.31 2.51e-9 Obesity-related traits; LIHC cis rs765787 0.530 rs1706830 chr15:45516229 G/A cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC cis rs67478160 0.619 rs10083370 chr14:104314182 G/A cg08213375 chr14:104286397 PPP1R13B -0.65 -12.49 -0.56 9.64e-30 Schizophrenia; LIHC cis rs3741404 0.757 rs2282492 chr11:63918589 A/G cg18225595 chr11:63971243 STIP1 0.67 10.53 0.49 1.2e-22 Platelet count; LIHC cis rs2580764 0.565 rs6760429 chr2:55228499 C/T cg09592903 chr2:55203963 RTN4 -0.72 -13.47 -0.59 1.86e-33 Mean platelet volume; LIHC cis rs6545883 0.791 rs2600665 chr2:61405795 G/T cg14146966 chr2:61757674 XPO1 0.4 6.68 0.34 9.77e-11 Tuberculosis; LIHC cis rs8049040 0.644 rs16973000 chr16:71493165 T/C cg06353428 chr16:71660113 MARVELD3 -0.76 -7.39 -0.37 1.12e-12 Blood protein levels; LIHC cis rs1008375 0.966 rs10939735 chr4:17578891 A/G cg16339924 chr4:17578868 LAP3 0.59 7.68 0.38 1.65e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7208859 0.623 rs9914499 chr17:29107588 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg12648201 chr2:27665141 KRTCAP3 -0.42 -5.82 -0.3 1.34e-8 Total body bone mineral density; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg05185784 chr16:90016020 DEF8 -0.47 -6.1 -0.31 2.87e-9 Skin colour saturation; LIHC trans rs17685 0.753 rs6953665 chr7:75769049 C/T cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10744422 1.000 rs1532835 chr12:123330665 G/A cg07706471 chr12:123319906 HIP1R -0.6 -7.94 -0.39 2.86e-14 Schizophrenia; LIHC cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg00750074 chr16:89608354 SPG7 0.43 6.82 0.35 4.15e-11 Multiple myeloma (IgH translocation); LIHC cis rs55665837 1.000 rs10832256 chr11:14442875 G/A cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs6456156 0.586 rs9457261 chr6:167467679 A/G cg12798992 chr6:167411361 FGFR1OP 0.43 6.65 0.34 1.18e-10 Primary biliary cholangitis; LIHC cis rs7552404 0.731 rs931507 chr1:76401577 G/A cg10523679 chr1:76189770 ACADM -0.57 -6.85 -0.35 3.39e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1577917 0.771 rs4441928 chr6:86241894 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 8.28 0.41 2.88e-15 Response to antipsychotic treatment; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg11070056 chr1:107600091 PRMT6 -0.7 -12.0 -0.54 6.27e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9814567 0.964 rs9820425 chr3:134223018 G/C cg06541857 chr3:134203789 ANAPC13;CEP63 -0.39 -5.76 -0.3 1.88e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3806843 0.676 rs2245643 chr5:140029780 C/T cg16179182 chr5:140090404 VTRNA1-1 0.37 6.16 0.32 2.04e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9640161 0.750 rs3735173 chr7:150020526 C/T cg17279839 chr7:150038598 RARRES2 0.49 10.45 0.49 2.33e-22 Blood protein levels;Circulating chemerin levels; LIHC cis rs288342 0.832 rs288307 chr2:183652094 C/T cg02625481 chr2:183667124 NA -0.29 -6.17 -0.32 1.96e-9 Recurrent major depressive disorder; LIHC cis rs7584330 0.704 rs7598954 chr2:238364776 C/T cg14458575 chr2:238380390 NA 0.53 7.53 0.38 4.49e-13 Prostate cancer; LIHC cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg05590025 chr7:65112418 INTS4L2 -0.59 -6.58 -0.34 1.81e-10 Diabetic kidney disease; LIHC cis rs2228479 0.850 rs17232910 chr16:89839766 G/C cg14709524 chr16:89940631 TCF25 0.48 5.89 0.3 9.25e-9 Skin colour saturation; LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg15383120 chr6:291909 DUSP22 -0.47 -6.07 -0.31 3.35e-9 Menopause (age at onset); LIHC trans rs1728785 1.000 rs1170434 chr16:68606590 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.3 0.32 8.94e-10 Ulcerative colitis; LIHC cis rs903552 1.000 rs12908079 chr15:102003820 C/A cg06707286 chr15:102010195 PCSK6 -0.44 -6.48 -0.33 3.2e-10 Diabetic kidney disease; LIHC trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg18110333 chr6:292329 DUSP22 -0.48 -6.57 -0.33 1.82e-10 Menopause (age at onset); LIHC cis rs7208859 0.673 rs999798 chr17:29158840 A/G cg13385521 chr17:29058706 SUZ12P 0.74 7.54 0.38 4.32e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7264396 0.790 rs6058294 chr20:34259396 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.32 -0.52 1.88e-25 Total cholesterol levels; LIHC cis rs651907 0.535 rs11717638 chr3:101505468 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg00106254 chr7:1943704 MAD1L1 -0.43 -6.92 -0.35 2.21e-11 Bipolar disorder and schizophrenia; LIHC cis rs11030122 0.673 rs11030639 chr11:4039056 A/G cg18678763 chr11:4115507 RRM1 -0.54 -8.14 -0.4 7.53e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs3008870 1.000 rs2755246 chr1:67488984 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.93 15.73 0.65 2.42e-42 Lymphocyte percentage of white cells; LIHC cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg02353165 chr6:42928485 GNMT 0.75 11.81 0.54 3.2e-27 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs7618501 1.000 rs7372730 chr3:49790682 C/G cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.63 -0.34 1.3100000000000001e-10 Intelligence (multi-trait analysis); LIHC cis rs7584330 0.554 rs3751110 chr2:238427142 T/C cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs743757 1.000 rs9835537 chr3:50464335 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.52 8.33 0.41 1.98e-15 Diastolic blood pressure; LIHC cis rs11864453 0.713 rs6680 chr16:72146570 T/C cg01557791 chr16:72042693 DHODH -0.47 -7.66 -0.38 1.98e-13 Fibrinogen levels; LIHC cis rs3859192 0.577 rs25645 chr17:38173143 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.93 0.65 3.83e-43 White blood cell count; LIHC cis rs1395 0.744 rs11686131 chr2:27508710 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -5.94 -0.31 7.05e-9 Blood metabolite levels; LIHC cis rs1448094 0.512 rs6539929 chr12:86244932 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs861318 0.702 rs74359395 chr1:159027003 A/G cg11003133 chr1:159046391 AIM2 -0.36 -7.02 -0.35 1.21e-11 Obesity-related traits; LIHC cis rs12464559 0.571 rs6741567 chr2:152578014 T/C cg01189475 chr2:152685088 ARL5A 0.67 7.88 0.39 4.55e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs9814567 1.000 rs28409322 chr3:134252385 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8078723 0.668 rs3859191 chr17:38128714 G/A cg17467752 chr17:38218738 THRA 0.63 10.89 0.51 6.46e-24 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs12699477 0.545 rs117125814 chr7:1910681 T/G cg14004847 chr7:1930337 MAD1L1 -0.45 -6.42 -0.33 4.63e-10 Testicular germ cell tumor; LIHC cis rs986417 0.818 rs10143831 chr14:61081961 G/T cg27398547 chr14:60952738 C14orf39 0.66 7.26 0.37 2.57e-12 Gut microbiota (bacterial taxa); LIHC cis rs9902453 0.726 rs3115092 chr17:28036350 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.56 0.59 8.23e-34 Coffee consumption (cups per day); LIHC cis rs2637030 0.559 rs256108 chr5:52874253 C/T cg06476337 chr5:52856530 NDUFS4 0.42 6.64 0.34 1.24e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs6545883 0.859 rs2694644 chr2:61604856 A/T cg15711740 chr2:61764176 XPO1 0.42 5.71 0.3 2.41e-8 Tuberculosis; LIHC trans rs61931739 0.500 rs11052966 chr12:34019826 C/T cg26384229 chr12:38710491 ALG10B 0.46 6.49 0.33 3.06e-10 Morning vs. evening chronotype; LIHC cis rs4853012 0.887 rs6737314 chr2:74339586 A/G cg20891558 chr2:74357851 NA 0.81 16.04 0.66 1.42e-43 Gestational age at birth (maternal effect); LIHC cis rs1046896 0.731 rs8067667 chr17:80785875 A/G cg02711726 chr17:80685570 FN3KRP -0.46 -8.38 -0.41 1.36e-15 Glycated hemoglobin levels; LIHC cis rs916888 0.779 rs430685 chr17:44859148 T/C cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs72627123 0.500 rs68148895 chr14:74529523 C/T cg05179529 chr14:74551516 LIN52;ALDH6A1 0.53 7.33 0.37 1.66e-12 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07424155 chr7:116503126 CAPZA2 -0.52 -7.16 -0.36 4.98e-12 Pancreatic cancer; LIHC cis rs4908768 0.906 rs12405049 chr1:8626117 C/T cg25722041 chr1:8623473 RERE 0.43 6.12 0.31 2.5e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4319547 0.614 rs10846764 chr12:122874297 T/C cg05707623 chr12:122985044 ZCCHC8 0.54 7.19 0.36 3.98e-12 Body mass index; LIHC cis rs11955398 0.625 rs11739209 chr5:59959767 T/C cg02684056 chr5:59996105 DEPDC1B 0.44 6.09 0.31 3e-9 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.927 rs6089593 chr20:60572312 G/A cg23262073 chr20:60523788 NA -0.28 -5.72 -0.3 2.33e-8 Body mass index; LIHC cis rs477895 1.000 rs7939107 chr11:64034773 C/T cg18225595 chr11:63971243 STIP1 0.64 6.55 0.33 2.15e-10 Mean platelet volume; LIHC cis rs637571 0.522 rs679581 chr11:65746653 A/G cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.82 0.3 1.39e-8 Eosinophil percentage of white cells; LIHC cis rs9486719 0.857 rs13208321 chr6:96860354 C/T cg06623918 chr6:96969491 KIAA0776 -0.6 -7.25 -0.36 2.86e-12 Migraine;Coronary artery disease; LIHC trans rs11098499 0.866 rs72676074 chr4:120359841 A/C cg25214090 chr10:38739885 LOC399744 0.6 9.73 0.47 6.29e-20 Corneal astigmatism; LIHC cis rs2839186 0.867 rs13050387 chr21:47701423 C/T cg12016809 chr21:47604291 C21orf56 0.41 5.97 0.31 6.06e-9 Testicular germ cell tumor; LIHC cis rs9596863 0.898 rs7328420 chr13:54320465 G/A ch.13.53330881F chr13:54432880 NA 0.44 5.99 0.31 5.36e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs17001868 0.892 rs117667045 chr22:40736961 C/T cg07138101 chr22:40742427 ADSL 0.58 6.05 0.31 3.71e-9 Mammographic density (dense area); LIHC cis rs17253792 0.822 rs28409547 chr14:56047826 C/T cg01858014 chr14:56050164 KTN1 -0.74 -8.03 -0.4 1.61e-14 Putamen volume; LIHC cis rs10883723 0.738 rs715438 chr10:104258303 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.66 0.56 2.23e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs60871478 0.679 rs6962050 chr7:817201 A/G cg04727924 chr7:799746 HEATR2 -0.62 -8.14 -0.4 7.42e-15 Cerebrospinal P-tau181p levels; LIHC cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg08888203 chr3:10149979 C3orf24 0.55 6.35 0.32 6.76e-10 Alzheimer's disease; LIHC cis rs9467773 1.000 rs12526680 chr6:26550954 A/G cg09904177 chr6:26538194 HMGN4 0.59 12.37 0.56 2.56e-29 Intelligence (multi-trait analysis); LIHC cis rs7772486 0.686 rs857875 chr6:145980033 T/G cg13319975 chr6:146136371 FBXO30 0.35 5.72 0.3 2.35e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs7766852 chr6:8472417 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.7 0.53 7.98e-27 Motion sickness; LIHC cis rs10771431 0.935 rs1988852 chr12:9372862 G/A cg08997352 chr12:9597637 DDX12 -0.51 -7.4 -0.37 1.07e-12 Breast size; LIHC cis rs7666738 0.680 rs11097613 chr4:99079991 G/T cg05340658 chr4:99064831 C4orf37 0.69 12.35 0.56 3.22e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs208520 0.545 rs6899712 chr6:66749670 T/C cg07460842 chr6:66804631 NA 0.83 14.8 0.62 1.15e-38 Exhaled nitric oxide output; LIHC cis rs3106136 0.681 rs11097420 chr4:95301035 C/G cg11021082 chr4:95130006 SMARCAD1 -0.34 -5.84 -0.3 1.24e-8 Capecitabine sensitivity; LIHC cis rs11605275 0.818 rs35645523 chr11:20046171 G/A cg14835545 chr11:20032148 NAV2 -0.6 -5.8 -0.3 1.48e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4478037 0.749 rs9681623 chr3:33131375 G/T cg27203090 chr3:33138513 GLB1;TMPPE -0.56 -7.42 -0.37 9.36e-13 Major depressive disorder; LIHC cis rs9303401 0.580 rs12946396 chr17:57164195 T/A cg25039879 chr17:56429692 SUPT4H1 0.76 8.62 0.42 2.57e-16 Cognitive test performance; LIHC trans rs2681424 0.966 rs1962532 chr3:121751531 C/T cg03946530 chr15:65596423 NA 0.5 6.43 0.33 4.27e-10 Multiple sclerosis; LIHC cis rs1892700 0.730 rs2834231 chr21:34892359 A/C cg14850771 chr21:34775459 IFNGR2 -0.45 -6.06 -0.31 3.54e-9 Educational attainment; LIHC cis rs2066819 1.000 rs77768890 chr12:56725121 A/G cg26714650 chr12:56694279 CS -1.4 -13.81 -0.6 8.69e-35 Psoriasis vulgaris; LIHC cis rs11166927 0.548 rs9324514 chr8:140830241 A/G cg16909799 chr8:140841666 TRAPPC9 0.52 8.27 0.41 3.08e-15 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs798554 0.679 rs7807978 chr7:2814635 C/T cg19717773 chr7:2847554 GNA12 -0.39 -7.09 -0.36 7.81e-12 Height; LIHC cis rs912057 0.841 rs1294423 chr6:6743795 C/T cg06612196 chr6:6737390 NA 0.53 9.98 0.48 9.08e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs8067545 0.611 rs7219615 chr17:20132558 T/A cg13482628 chr17:19912719 NA -0.43 -6.98 -0.35 1.55e-11 Schizophrenia; LIHC cis rs881375 0.678 rs3761846 chr9:123689597 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 5.94 0.31 7.16e-9 Rheumatoid arthritis; LIHC cis rs7647973 1.000 rs3866330 chr3:49582994 T/C cg07636037 chr3:49044803 WDR6 0.51 6.45 0.33 3.74e-10 Menarche (age at onset); LIHC trans rs10411161 0.748 rs78410648 chr19:52399401 G/A cg22319618 chr22:45562946 NUP50 -0.65 -7.43 -0.37 8.54e-13 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25411849 chr6:89855994 PM20D2 -0.4 -6.25 -0.32 1.19e-9 Pancreatic cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27233612 chr3:25824257 NGLY1 0.39 6.12 0.31 2.52e-9 Pancreatic cancer; LIHC cis rs7903847 0.642 rs6584127 chr10:99142948 A/C cg06359132 chr10:99160096 RRP12 -0.42 -6.43 -0.33 4.18e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs4555082 0.645 rs2816605 chr14:105715515 C/T cg06808227 chr14:105710500 BRF1 -0.5 -6.1 -0.31 2.9e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs3796619 1.000 rs1466215 chr4:1072220 C/T cg27284194 chr4:1044797 NA 0.62 10.36 0.49 4.56e-22 Recombination rate (males); LIHC cis rs2836974 0.565 rs2836939 chr21:40578546 C/T cg17971929 chr21:40555470 PSMG1 0.71 6.28 0.32 1.03e-9 Cognitive function; LIHC cis rs796364 0.789 rs176008 chr2:200814720 A/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.51 0.46 3.54e-19 Schizophrenia; LIHC cis rs7959452 0.590 rs28778648 chr12:69771911 C/A cg22834771 chr12:69754056 YEATS4 -0.52 -9.27 -0.45 2.09e-18 Blood protein levels; LIHC cis rs2108622 0.527 rs67617968 chr19:15977565 A/G cg13772218 chr19:15982569 NA 0.35 7.56 0.38 3.72e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg03129853 chr11:93862749 PANX1 -0.55 -6.49 -0.33 2.93e-10 Lung function (FEV1); LIHC cis rs3824867 0.959 rs4237544 chr11:47454271 G/T cg20307385 chr11:47447363 PSMC3 -0.58 -8.04 -0.4 1.45e-14 Mean corpuscular hemoglobin; LIHC cis rs4728302 0.869 rs6943986 chr7:133616965 G/A cg10665199 chr7:133106180 EXOC4 0.38 6.48 0.33 3.24e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs3812111 0.866 rs9488837 chr6:116435957 G/A cg08036074 chr6:116424633 NT5DC1 -0.65 -11.18 -0.52 5.86e-25 Age-related macular degeneration; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg11494091 chr17:61959527 GH2 0.45 8.32 0.41 2.12e-15 Prudent dietary pattern; LIHC cis rs703842 0.616 rs1875125 chr12:58227241 T/G cg18357645 chr12:58087776 OS9 -0.43 -6.07 -0.31 3.39e-9 Multiple sclerosis; LIHC cis rs7309 0.810 rs11684253 chr2:162034536 G/T cg13854012 chr2:162103682 NA -0.35 -6.52 -0.33 2.46e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg11764359 chr7:65958608 NA 0.59 6.26 0.32 1.18e-9 Diabetic kidney disease; LIHC cis rs1371867 0.846 rs1660353 chr8:101250907 C/T cg06002616 chr8:101225028 SPAG1 0.34 5.94 0.31 6.98e-9 Atrioventricular conduction; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04471375 chr16:58752165 GOT2 -0.37 -6.08 -0.31 3.25e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs782590 0.934 rs62165184 chr2:55788253 G/C cg18811423 chr2:55921094 PNPT1 0.94 15.5 0.64 1.98e-41 Metabolic syndrome; LIHC cis rs4699052 0.963 rs11097801 chr4:104150323 A/G cg16532752 chr4:104119610 CENPE -0.41 -6.63 -0.34 1.28e-10 Testicular germ cell tumor; LIHC cis rs1865760 0.551 rs9461230 chr6:26019240 G/C cg18357526 chr6:26021779 HIST1H4A 0.52 7.67 0.38 1.83e-13 Height; LIHC cis rs67460515 0.500 rs964533 chr3:160749019 C/A cg03342759 chr3:160939853 NMD3 -0.43 -5.87 -0.3 1.01e-8 Parkinson's disease; LIHC cis rs74181299 0.571 rs71424153 chr2:65280894 G/C cg05010058 chr2:65284262 CEP68 0.37 5.94 0.31 7.05e-9 Pulse pressure; LIHC cis rs4742903 0.904 rs12380062 chr9:106941903 A/G cg14250997 chr9:106856677 SMC2 0.35 5.92 0.3 7.73e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs17685 0.712 rs6953342 chr7:75776753 T/C cg01364799 chr7:75623366 TMEM120A -0.41 -6.12 -0.31 2.5e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.88 0.3 9.86e-9 Menopause (age at onset); LIHC cis rs8083850 0.572 rs7235888 chr18:50879701 A/T cg24270629 chr18:50823537 DCC -0.57 -8.65 -0.42 2.06e-16 Intelligence (multi-trait analysis); LIHC cis rs881375 1.000 rs10818480 chr9:123643170 T/C cg14580859 chr9:123691850 NA 0.38 6.7 0.34 8.79e-11 Rheumatoid arthritis; LIHC cis rs7592578 0.766 rs62182865 chr2:191434180 T/C cg10560079 chr2:191398806 TMEM194B -0.89 -12.58 -0.56 4.34e-30 Diastolic blood pressure; LIHC cis rs1062177 0.756 rs2915817 chr5:151115517 T/C cg00977110 chr5:151150581 G3BP1 -0.57 -7.21 -0.36 3.73e-12 Preschool internalizing problems; LIHC cis rs7707921 0.522 rs10065463 chr5:81500280 A/G cg15871215 chr5:81402204 ATG10 -0.59 -8.19 -0.4 5.35e-15 Breast cancer; LIHC cis rs12824058 0.831 rs55726136 chr12:130810312 G/A cg24229701 chr12:130821962 PIWIL1 0.44 6.78 0.34 5.4e-11 Menopause (age at onset); LIHC cis rs507080 0.769 rs483283 chr11:118506402 T/C cg04173919 chr11:118528438 PHLDB1 0.31 5.72 0.3 2.34e-8 Serum metabolite levels; LIHC cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.47 0.49 1.98e-22 Vitiligo; LIHC cis rs7582720 1.000 rs72936304 chr2:204036357 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.05 0.31 3.84e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7208859 0.623 rs78071511 chr17:29128154 C/T cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3806843 1.000 rs3806845 chr5:140180737 C/T cg19875535 chr5:140030758 IK 0.37 5.96 0.31 6.29e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs11098499 0.754 rs1980026 chr4:120251643 C/A cg25214090 chr10:38739885 LOC399744 0.51 8.29 0.41 2.61e-15 Corneal astigmatism; LIHC cis rs7824557 0.603 rs2246606 chr8:11219334 G/A cg21775007 chr8:11205619 TDH 0.51 5.83 0.3 1.26e-8 Retinal vascular caliber; LIHC cis rs8180040 0.800 rs7632501 chr3:47268306 T/C cg16586182 chr3:47516702 SCAP 0.51 9.01 0.44 1.45e-17 Colorectal cancer; LIHC cis rs9359856 0.600 rs1179899 chr6:90320258 C/T cg13799429 chr6:90582589 CASP8AP2 -0.64 -6.9 -0.35 2.5e-11 Bipolar disorder; LIHC cis rs1775715 0.870 rs3847414 chr10:32219176 A/G cg14930904 chr10:32216787 ARHGAP12 0.38 6.77 0.34 5.61e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs3008870 0.755 rs10749766 chr1:67376921 A/G cg02640540 chr1:67518911 SLC35D1 0.41 6.49 0.33 3.1e-10 Lymphocyte percentage of white cells; LIHC cis rs4819052 0.851 rs7275870 chr21:46671214 C/T cg11663144 chr21:46675770 NA -0.32 -5.95 -0.31 6.7e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8180040 0.620 rs6442055 chr3:47110722 A/G cg16586182 chr3:47516702 SCAP -0.49 -8.7 -0.43 1.38e-16 Colorectal cancer; LIHC cis rs919433 0.589 rs7601800 chr2:198395099 T/C cg10820045 chr2:198174542 NA 0.5 7.86 0.39 4.89e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3806701 0.619 rs6442008 chr3:46645753 C/T cg16875182 chr3:46619291 LRRC2;TDGF1 -0.55 -6.49 -0.33 2.94e-10 Blood protein levels; LIHC cis rs763121 0.853 rs2064088 chr22:39053382 A/G cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs68170813 0.559 rs6964798 chr7:106933013 C/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.24e-9 Coronary artery disease; LIHC cis rs7224737 1.000 rs7219220 chr17:40294280 T/C cg00647820 chr17:40259828 DHX58 -0.28 -5.91 -0.3 8.35e-9 Fibrinogen levels; LIHC cis rs12928939 0.774 rs7205340 chr16:71645670 A/T cg03805757 chr16:71968109 PKD1L3 0.51 6.33 0.32 7.53e-10 Post bronchodilator FEV1; LIHC cis rs11622475 0.677 rs12889842 chr14:104344947 G/T cg12183467 chr14:104352244 NA -0.49 -7.19 -0.36 4.12e-12 Bipolar disorder; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10073129 chr8:67974421 COPS5 0.39 6.14 0.32 2.3e-9 Calcium levels; LIHC cis rs1419980 0.673 rs12146828 chr12:7739341 C/G cg10578777 chr12:7781093 NA -0.45 -7.86 -0.39 5.06e-14 HDL cholesterol levels; LIHC trans rs116095464 0.558 rs11959126 chr5:283880 T/G cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.83 -0.35 3.99e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6977660 0.714 rs12700075 chr7:19791476 G/T cg07541023 chr7:19748670 TWISTNB 0.51 7.48 0.38 6.14e-13 Thyroid stimulating hormone; LIHC cis rs433852 0.904 rs8102492 chr19:49140809 A/C cg10736770 chr19:49115456 FAM83E -0.41 -6.95 -0.35 1.87e-11 Elevated serum carcinoembryonic antigen levels;Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs2281845 0.929 rs6413915 chr1:201091041 A/C cg24849736 chr1:201084428 NA 0.39 7.96 0.4 2.62e-14 Permanent tooth development; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04588562 chr17:46756094 NA 0.46 6.58 0.34 1.73e-10 Pancreatic cancer; LIHC cis rs2191566 0.664 rs4803669 chr19:44539962 C/A cg20607764 chr19:44506953 ZNF230 -0.36 -5.98 -0.31 5.63e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs473651 0.935 rs482775 chr2:239335403 G/C cg18131467 chr2:239335373 ASB1 1.09 20.85 0.75 6.7e-63 Multiple system atrophy; LIHC cis rs7635838 0.819 rs7637414 chr3:11522228 C/G cg00170343 chr3:11313890 ATG7 0.41 6.27 0.32 1.06e-9 HDL cholesterol; LIHC cis rs1801251 1.000 rs283480 chr2:233648742 G/A cg08000102 chr2:233561755 GIGYF2 0.78 11.75 0.54 5.35e-27 Coronary artery disease; LIHC cis rs4969178 0.930 rs7208596 chr17:76396528 C/G cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs1865760 1.000 rs9358895 chr6:25924655 C/T cg17691542 chr6:26056736 HIST1H1C 0.4 6.09 0.31 3.09e-9 Height; LIHC trans rs9929218 0.906 rs34565494 chr16:68741769 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.65 -9.33 -0.45 1.4e-18 Colorectal cancer; LIHC cis rs7818382 0.967 rs7812465 chr8:96050557 C/T cg13393036 chr8:95962371 TP53INP1 0.33 7.95 0.4 2.67e-14 Alzheimer's disease (late onset); LIHC cis rs929354 0.772 rs2023977 chr7:156996022 C/G cg17757837 chr7:157058334 UBE3C 0.74 12.11 0.55 2.47e-28 Body mass index; LIHC cis rs12908161 0.959 rs12908699 chr15:85240403 G/T cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs7945718 0.967 rs12291695 chr11:12795662 A/G cg25843174 chr11:12811716 TEAD1 -0.36 -8.27 -0.41 2.99e-15 Educational attainment (years of education); LIHC cis rs4650994 0.571 rs6676507 chr1:178508743 C/G cg05350800 chr1:178550844 NA -0.3 -6.47 -0.33 3.41e-10 HDL cholesterol levels;HDL cholesterol; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18786515 chr8:10207915 MSRA 0.45 6.2 0.32 1.61e-9 Longevity; LIHC cis rs6466055 0.669 rs6950620 chr7:104770386 A/G cg04380332 chr7:105027541 SRPK2 0.32 6.63 0.34 1.3e-10 Schizophrenia; LIHC cis rs600806 0.815 rs4970754 chr1:109969721 A/G cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.54 -0.38 4.39e-13 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg18538332 chr22:24372958 LOC391322 -0.63 -9.19 -0.44 3.96e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05318427 chr2:85199320 KCMF1 0.48 6.92 0.35 2.28e-11 Pancreatic cancer; LIHC cis rs7945718 0.591 rs10831892 chr11:12676272 T/A cg25843174 chr11:12811716 TEAD1 0.33 7.71 0.38 1.42e-13 Educational attainment (years of education); LIHC cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg06634786 chr22:41940651 POLR3H 0.76 7.78 0.39 8.57e-14 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1198430 0.683 rs1198440 chr1:23780861 C/A cg19827787 chr1:23763612 ASAP3 0.28 5.99 0.31 5.29e-9 Total cholesterol levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09590193 chr11:105947389 KBTBD3;AASDHPPT 0.42 6.24 0.32 1.27e-9 Cognitive function; LIHC cis rs6582630 0.634 rs10748443 chr12:38734062 G/T cg26384229 chr12:38710491 ALG10B 0.59 8.28 0.41 2.77e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs1552244 0.882 rs6443276 chr3:10008905 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.58 -0.5 8.39e-23 Alzheimer's disease; LIHC cis rs11577318 0.853 rs7537477 chr1:26618829 C/T cg10402321 chr1:26617780 UBXN11 -0.37 -5.78 -0.3 1.65e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs1707322 0.963 rs11211238 chr1:46449415 G/A cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13392177 0.660 rs62185964 chr2:219073745 A/G cg00012203 chr2:219082015 ARPC2 -0.75 -11.24 -0.52 3.6e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs6973256 0.543 rs13243553 chr7:133506955 A/G cg03336402 chr7:133662267 EXOC4 0.4 6.15 0.32 2.14e-9 Intelligence (multi-trait analysis); LIHC cis rs9918079 0.560 rs12651550 chr4:15641018 G/C cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.86 -0.3 1.09e-8 Obesity-related traits; LIHC cis rs36051895 0.594 rs10115464 chr9:5144268 C/T cg02405213 chr9:5042618 JAK2 -0.67 -11.75 -0.54 5.35e-27 Pediatric autoimmune diseases; LIHC cis rs4474465 0.646 rs10899556 chr11:78278986 C/T cg27205649 chr11:78285834 NARS2 0.5 7.82 0.39 6.79e-14 Alzheimer's disease (survival time); LIHC cis rs738322 0.742 rs4821767 chr22:38614129 G/T cg25457927 chr22:38595422 NA 0.26 6.5 0.33 2.91e-10 Cutaneous nevi; LIHC cis rs6835098 0.961 rs2877748 chr4:174102397 G/A cg27433088 chr4:174089019 GALNT7 0.41 7.01 0.35 1.25e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs35110281 0.782 rs2329442 chr21:45041790 T/C cg01579765 chr21:45077557 HSF2BP -0.35 -6.58 -0.34 1.72e-10 Mean corpuscular volume; LIHC cis rs7208859 0.623 rs11657662 chr17:29076347 A/G cg14067834 chr17:29058358 SUZ12P -0.67 -6.74 -0.34 6.63e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs5769765 0.819 rs9616379 chr22:50312035 C/T cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs10876993 0.890 rs774888 chr12:58036506 A/G cg15848620 chr12:58087721 OS9 -0.55 -7.52 -0.38 4.99e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7216064 0.861 rs73352810 chr17:65875184 G/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs240764 0.817 rs240110 chr6:101059629 T/C cg09795085 chr6:101329169 ASCC3 0.52 7.23 0.36 3.15e-12 Neuroticism; LIHC cis rs600806 0.778 rs11101960 chr1:110008778 C/T cg10127483 chr1:110009974 SYPL2 0.47 5.98 0.31 5.6e-9 Intelligence (multi-trait analysis); LIHC cis rs727505 1.000 rs10240673 chr7:124513050 A/G cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.1e-9 Lewy body disease; LIHC cis rs798554 0.797 rs798494 chr7:2798294 C/A cg19717773 chr7:2847554 GNA12 -0.4 -6.45 -0.33 3.74e-10 Height; LIHC cis rs7552404 0.727 rs5745433 chr1:76333163 T/G cg03433033 chr1:76189801 ACADM 0.56 7.14 0.36 5.62e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs780096 0.546 rs715325 chr2:27725572 C/A cg05484376 chr2:27715224 FNDC4 0.39 6.64 0.34 1.26e-10 Total body bone mineral density; LIHC cis rs9326248 1.000 rs3736120 chr11:117032125 G/T cg26566898 chr11:117069891 TAGLN 0.51 7.9 0.39 3.81e-14 Blood protein levels; LIHC cis rs12200782 0.530 rs6929908 chr6:26555289 C/A cg12826209 chr6:26865740 GUSBL1 0.49 6.0 0.31 5.07e-9 Small cell lung carcinoma; LIHC cis rs881375 0.967 rs1930780 chr9:123686219 C/G cg14580859 chr9:123691850 NA 0.37 6.53 0.33 2.42e-10 Rheumatoid arthritis; LIHC cis rs11696739 0.513 rs34600126 chr20:1597433 G/T cg15722679 chr20:1638393 SIRPG 0.54 9.88 0.47 2.01e-20 Mean platelet volume; LIHC trans rs35110281 0.627 rs56369437 chr21:44970275 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.63 0.34 1.3100000000000001e-10 Mean corpuscular volume; LIHC cis rs1997103 1.000 rs9642580 chr7:55400359 G/A cg17469321 chr7:55412551 NA 0.47 7.01 0.35 1.31e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs3770081 1.000 rs735737 chr2:86177101 G/T cg01119172 chr2:86362222 SNORD94;PTCD3 0.39 5.83 0.3 1.27e-8 Facial emotion recognition (sad faces); LIHC cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg11764359 chr7:65958608 NA 0.65 6.36 0.33 6.62e-10 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg18252515 chr7:66147081 NA 1.27 16.64 0.67 5.64e-46 Diabetic kidney disease; LIHC cis rs7945071 0.507 rs11213397 chr11:110296813 A/G cg04157658 chr11:110243994 NA 0.34 6.23 0.32 1.4e-9 Cognitive function; LIHC cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.6 8.88 0.43 3.86e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs9560113 0.959 rs4773385 chr13:112178452 C/T cg14154082 chr13:112174009 NA 0.29 6.14 0.32 2.28e-9 Menarche (age at onset); LIHC cis rs9910055 0.530 rs8072954 chr17:42294722 G/A cg08499158 chr17:42289980 UBTF -0.48 -7.81 -0.39 7.16e-14 Total body bone mineral density; LIHC cis rs7927771 1.000 rs12419692 chr11:47624714 A/C cg20307385 chr11:47447363 PSMC3 0.45 5.87 0.3 1.05e-8 Subjective well-being; LIHC cis rs8180040 0.932 rs12489046 chr3:47527683 T/G cg16586182 chr3:47516702 SCAP -0.58 -11.26 -0.52 3.21e-25 Colorectal cancer; LIHC cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg24250549 chr1:154909240 PMVK 0.65 10.02 0.48 7.06e-21 Prostate cancer; LIHC cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.47 0.46 4.88e-19 Platelet count; LIHC cis rs9486719 1.000 rs11756315 chr6:97008678 A/G cg06623918 chr6:96969491 KIAA0776 0.67 7.13 0.36 6.11e-12 Migraine;Coronary artery disease; LIHC cis rs9326778 0.520 rs6882181 chr5:108823545 G/A cg17395555 chr5:108820864 NA -0.37 -6.24 -0.32 1.27e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs1577917 0.958 rs11756510 chr6:86699794 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.64 -0.34 1.24e-10 Response to antipsychotic treatment; LIHC trans rs9531686 0.967 rs9531685 chr13:85549282 A/G cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.25 0.32 1.19e-9 Anorexia nervosa; LIHC cis rs7520050 0.807 rs5021934 chr1:46109304 A/G cg03146154 chr1:46216737 IPP -0.5 -8.52 -0.42 5.21e-16 Red blood cell count;Reticulocyte count; LIHC cis rs9309473 0.687 rs6706235 chr2:73613558 C/G cg20560298 chr2:73613845 ALMS1 -0.47 -7.54 -0.38 4.37e-13 Metabolite levels; LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg12016809 chr21:47604291 C21orf56 0.4 5.86 0.3 1.07e-8 Testicular germ cell tumor; LIHC cis rs8081395 0.801 rs2777895 chr17:57879610 A/G cg02344993 chr17:57696989 CLTC -0.44 -7.28 -0.37 2.31e-12 White blood cell count; LIHC cis rs7824557 0.614 rs2736286 chr8:11227104 A/G cg21775007 chr8:11205619 TDH -0.59 -9.31 -0.45 1.62e-18 Retinal vascular caliber; LIHC cis rs1403694 0.695 rs10439971 chr3:186434188 C/T cg12454167 chr3:186435060 KNG1 0.38 8.97 0.44 2.01e-17 Blood protein levels; LIHC cis rs6754311 0.550 rs10173394 chr2:136522675 C/T cg15123519 chr2:136567270 LCT 0.44 8.77 0.43 8.42e-17 Mosquito bite size; LIHC cis rs244293 0.894 rs244372 chr17:53185212 G/C cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs35883536 0.609 rs1855631 chr1:101040010 C/T cg14515779 chr1:101123966 NA 0.46 6.56 0.33 2.04e-10 Monocyte count; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg22100476 chr1:43638037 WDR65;EBNA1BP2 -0.43 -6.27 -0.32 1.06e-9 Bipolar disorder; LIHC cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs10751667 1.000 rs7396798 chr11:970510 G/T cg10932868 chr11:921992 NA 0.36 6.77 0.34 5.46e-11 Alzheimer's disease (late onset); LIHC cis rs875971 0.597 rs11771318 chr7:66062480 G/T cg18876405 chr7:65276391 NA -0.43 -6.6 -0.34 1.55e-10 Aortic root size; LIHC cis rs34779708 0.733 rs3853672 chr10:35549606 A/C cg03585969 chr10:35415529 CREM 0.74 10.61 0.5 6.28e-23 Inflammatory bowel disease;Crohn's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17930852 chr1:45957182 TESK2 0.45 6.61 0.34 1.48e-10 Pancreatic cancer; LIHC cis rs9916302 0.808 rs6503515 chr17:37606433 G/T cg00129232 chr17:37814104 STARD3 -0.41 -6.61 -0.34 1.45e-10 Glomerular filtration rate (creatinine); LIHC cis rs7772486 0.713 rs1986729 chr6:146194831 G/A cg23711669 chr6:146136114 FBXO30 0.72 12.91 0.57 2.49e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.642 rs7078782 chr10:99168604 C/T cg06359132 chr10:99160096 RRP12 -0.38 -5.96 -0.31 6.4e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7937682 0.889 rs558736 chr11:111500760 C/G cg09085632 chr11:111637200 PPP2R1B -1.03 -12.24 -0.55 7.9e-29 Primary sclerosing cholangitis; LIHC cis rs7772486 0.875 rs10457793 chr6:146415403 A/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.11 -0.31 2.75e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3749237 0.595 rs4855864 chr3:49521974 C/T cg07636037 chr3:49044803 WDR6 0.53 8.08 0.4 1.1e-14 Resting heart rate; LIHC cis rs561341 0.843 rs879945 chr17:30242796 G/A cg13647721 chr17:30228624 UTP6 0.71 7.37 0.37 1.29e-12 Hip circumference adjusted for BMI; LIHC cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.3 0.45 1.74e-18 Bipolar disorder; LIHC cis rs7258465 1.000 rs10425982 chr19:18586519 T/A cg10790698 chr19:18539756 SSBP4 -0.35 -7.43 -0.37 8.68e-13 Breast cancer; LIHC cis rs1799949 0.602 rs8176257 chr17:41216205 G/T cg05368731 chr17:41323189 NBR1 0.65 10.29 0.49 8.29e-22 Menopause (age at onset); LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg06873352 chr17:61820015 STRADA 0.56 8.42 0.41 1.04e-15 Height; LIHC cis rs28830936 0.966 rs2303518 chr15:42109975 T/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.29 -0.32 9.79e-10 Diastolic blood pressure; LIHC cis rs9858542 1.000 rs9822268 chr3:49719729 G/A cg02487422 chr3:49467188 NICN1 -0.44 -5.79 -0.3 1.63e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs3106136 0.778 rs1593554 chr4:95278501 C/T cg11021082 chr4:95130006 SMARCAD1 0.38 6.48 0.33 3.16e-10 Capecitabine sensitivity; LIHC cis rs2842992 0.747 rs1547093 chr6:160205991 C/A cg11366901 chr6:160182831 ACAT2 0.9 15.24 0.64 2.16e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs34779708 0.897 rs9787566 chr10:35279455 T/A cg03585969 chr10:35415529 CREM 0.87 13.04 0.58 7.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3796352 1.000 rs34943350 chr3:53012888 C/T cg07884673 chr3:53033167 SFMBT1 0.99 6.88 0.35 2.8e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7937682 0.814 rs1784788 chr11:111486136 T/G cg22437258 chr11:111473054 SIK2 0.51 5.8 0.3 1.55e-8 Primary sclerosing cholangitis; LIHC cis rs16828019 0.852 rs12742803 chr1:41648131 G/A cg03962019 chr1:41807865 NA 0.53 7.53 0.38 4.66e-13 Intelligence (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg25749165 chr10:75634242 CAMK2G 0.41 6.44 0.33 3.94e-10 Calcium levels; LIHC cis rs644799 0.896 rs4430471 chr11:95646774 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.46 6.28 0.32 1.04e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11764590 0.694 rs6977161 chr7:2099361 T/C cg23043544 chr7:2124092 MAD1L1 -0.41 -6.61 -0.34 1.49e-10 Neuroticism; LIHC cis rs244293 0.760 rs1990673 chr17:53050025 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.48 -7.21 -0.36 3.52e-12 Menarche (age at onset); LIHC cis rs559928 0.593 rs112275221 chr11:63936994 C/T cg02228329 chr11:64053129 BAD;GPR137 0.62 5.75 0.3 2e-8 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs10751667 1.000 rs10794349 chr11:945678 T/C cg06064525 chr11:970664 AP2A2 -0.5 -12.55 -0.56 5.67e-30 Alzheimer's disease (late onset); LIHC cis rs344364 0.511 rs1657134 chr16:1953127 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.57 -7.51 -0.38 5.04e-13 Glomerular filtration rate in chronic kidney disease; LIHC cis rs7953508 0.506 rs10859532 chr12:93960917 G/C cg18151635 chr12:93972918 NA -0.51 -8.54 -0.42 4.49e-16 Pubertal anthropometrics; LIHC cis rs4728302 0.869 rs2042456 chr7:133580447 G/A cg10665199 chr7:133106180 EXOC4 0.36 6.26 0.32 1.13e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs739401 0.611 rs2071104 chr11:3036933 G/T cg25174290 chr11:3078921 CARS 0.62 9.47 0.46 4.77e-19 Longevity; LIHC cis rs950776 0.518 rs11630349 chr15:78824608 C/T cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs6748734 1.000 rs11898716 chr2:241828311 A/G cg20140201 chr2:241835670 C2orf54 -0.47 -6.4 -0.33 5.18e-10 Urinary metabolites; LIHC trans rs11098499 0.909 rs28714195 chr4:120316950 A/T cg25214090 chr10:38739885 LOC399744 0.58 9.18 0.44 4.22e-18 Corneal astigmatism; LIHC cis rs1577917 0.958 rs2121594 chr6:86576854 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.3 -0.37 2e-12 Response to antipsychotic treatment; LIHC cis rs7927592 0.913 rs7109294 chr11:68332093 A/G cg01657329 chr11:68192670 LRP5 -0.48 -6.25 -0.32 1.24e-9 Total body bone mineral density; LIHC cis rs16944613 0.510 rs4932350 chr15:91143438 A/G cg26821196 chr15:91095069 CRTC3 0.33 6.22 0.32 1.44e-9 Colorectal cancer; LIHC cis rs9341808 0.527 rs7453746 chr6:80810013 T/G cg08355045 chr6:80787529 NA 0.37 7.61 0.38 2.65e-13 Sitting height ratio; LIHC cis rs1975974 1.000 rs7224508 chr17:21722352 T/A cg18423549 chr17:21743878 NA -0.46 -6.08 -0.31 3.28e-9 Psoriasis; LIHC cis rs1799949 1.000 rs8070085 chr17:41341984 C/T cg23758822 chr17:41437982 NA -0.85 -15.29 -0.64 1.41e-40 Menopause (age at onset); LIHC cis rs4808199 1.000 rs7258508 chr19:19475469 T/C cg03709012 chr19:19516395 GATAD2A 1.04 17.13 0.68 6.37e-48 Nonalcoholic fatty liver disease; LIHC cis rs4820539 1.000 rs13054985 chr22:23458577 G/A cg21100191 chr22:23484243 RTDR1 0.88 15.68 0.65 4.01e-42 Bone mineral density; LIHC cis rs4665809 1.000 rs2891490 chr2:26325927 T/C cg27170947 chr2:26402098 FAM59B -0.65 -8.22 -0.41 4.22e-15 Gut microbiome composition (summer); LIHC cis rs9649213 0.593 rs6465682 chr7:98016417 C/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.79 -0.3 1.56e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs3960554 0.733 rs59170362 chr7:75629267 G/C cg19862616 chr7:65841803 NCRNA00174 0.57 7.81 0.39 7.31e-14 Eotaxin levels; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg01339444 chr6:118972232 C6orf204 0.59 5.93 0.31 7.53e-9 Diastolic blood pressure; LIHC cis rs7772486 0.875 rs2474356 chr6:146296798 G/A cg23711669 chr6:146136114 FBXO30 0.67 11.78 0.54 4.11e-27 Lobe attachment (rater-scored or self-reported); LIHC trans rs3960554 0.808 rs2286829 chr7:75677739 G/A cg19862616 chr7:65841803 NCRNA00174 0.6 8.37 0.41 1.45e-15 Eotaxin levels; LIHC cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg05564831 chr3:52568323 NT5DC2 0.37 6.03 0.31 4.19e-9 Bipolar disorder; LIHC cis rs2304069 0.644 rs216131 chr5:149431223 C/T cg12661370 chr5:149340060 SLC26A2 0.49 6.03 0.31 4.27e-9 HIV-1 control; LIHC cis rs3790645 1.000 rs369385 chr1:26893229 C/T cg23229016 chr1:26872525 RPS6KA1 0.23 5.75 0.3 1.95e-8 Glucose homeostasis traits; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg20760063 chr17:41277580 NBR2;BRCA1 -0.42 -6.48 -0.33 3.28e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg00149659 chr3:10157352 C3orf10 0.68 7.2 0.36 3.97e-12 Alzheimer's disease; LIHC cis rs77861329 0.925 rs72964042 chr3:52088485 A/C cg08692210 chr3:52188851 WDR51A 0.84 7.61 0.38 2.76e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs912057 0.833 rs1294424 chr6:6744135 G/A cg06612196 chr6:6737390 NA 0.53 9.98 0.48 9.08e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.37 0.41 1.55e-15 Platelet count; LIHC cis rs826838 1.000 rs4575342 chr12:38663831 G/A cg13010199 chr12:38710504 ALG10B 0.64 7.58 0.38 3.2e-13 Heart rate; LIHC cis rs8062405 0.755 rs56209193 chr16:28585636 C/T cg07451762 chr16:28383216 NA 0.41 7.29 0.37 2.1e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs611744 0.967 rs612265 chr8:109188650 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.64e-11 Dupuytren's disease; LIHC cis rs9916302 0.861 rs11078896 chr17:37415544 C/T cg03013999 chr17:37608204 MED1 0.36 6.1 0.31 2.85e-9 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.763 rs10896351 chr11:68386896 G/A cg20283391 chr11:68216788 NA -0.39 -6.21 -0.32 1.57e-9 Total body bone mineral density; LIHC cis rs8044995 0.563 rs3785116 chr16:68372730 G/A cg05110241 chr16:68378359 PRMT7 -0.92 -10.27 -0.49 9.39e-22 Schizophrenia; LIHC cis rs4808199 0.901 rs11669516 chr19:19532682 G/A cg03709012 chr19:19516395 GATAD2A 1.07 19.02 0.72 1.49e-55 Nonalcoholic fatty liver disease; LIHC cis rs769267 0.895 rs2965182 chr19:19548246 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.01 0.4 1.82e-14 Tonsillectomy; LIHC cis rs79149102 0.579 rs28394281 chr15:75326754 C/G cg15902774 chr15:75289873 SCAMP5 0.45 6.8 0.35 4.58e-11 Lung cancer; LIHC cis rs7474896 0.559 rs1735629 chr10:38178309 C/T cg25427524 chr10:38739819 LOC399744 0.46 5.92 0.3 7.9e-9 Obesity (extreme); LIHC cis rs968567 0.559 rs174544 chr11:61567753 C/A cg07689907 chr11:61582574 FADS1 0.41 5.96 0.31 6.2e-9 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs1046896 0.739 rs2379358 chr17:80741612 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.53 8.39 0.41 1.29e-15 Glycated hemoglobin levels; LIHC cis rs2404602 0.684 rs965818 chr15:76866785 T/C cg03037974 chr15:76606532 NA -0.61 -10.2 -0.48 1.64e-21 Blood metabolite levels; LIHC cis rs8180040 0.593 rs10433549 chr3:47031433 C/T cg16586182 chr3:47516702 SCAP 0.48 8.58 0.42 3.43e-16 Colorectal cancer; LIHC cis rs2292864 0.764 rs1969269 chr17:45335537 C/A cg18085866 chr17:45331354 ITGB3 -0.62 -6.79 -0.34 4.89e-11 Left atrial antero-posterior diameter; LIHC cis rs6089584 0.888 rs6061983 chr20:60621202 T/C cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs801193 0.967 rs2707841 chr7:66157020 A/G cg11764359 chr7:65958608 NA 0.71 10.74 0.5 2.3e-23 Aortic root size; LIHC trans rs7246657 0.943 rs3803895 chr19:37898669 A/G cg10208301 chr11:6592745 DNHD1 0.47 6.73 0.34 7.31e-11 Coronary artery calcification; LIHC cis rs892961 1.000 rs11077907 chr17:75400706 G/A cg01320579 chr17:75405842 SEPT9 0.5 6.52 0.33 2.53e-10 Airflow obstruction; LIHC cis rs7572733 0.534 rs1436131 chr2:198731230 A/C cg00792783 chr2:198669748 PLCL1 0.46 6.73 0.34 7.19e-11 Dermatomyositis; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC cis rs898097 0.510 rs10445242 chr17:80891666 G/T cg15664640 chr17:80829946 TBCD 0.43 7.22 0.36 3.34e-12 Breast cancer; LIHC cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.01 0.31 4.83e-9 Menopause (age at onset); LIHC cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg19318889 chr4:1322082 MAEA 0.46 6.49 0.33 3.11e-10 Obesity-related traits; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs709400 0.663 rs62007687 chr14:103903763 G/T cg26031613 chr14:104095156 KLC1 0.78 10.09 0.48 3.97e-21 Body mass index; LIHC cis rs6138458 0.585 rs1007881 chr20:25014385 A/G cg26195577 chr20:24973756 C20orf3 0.78 9.85 0.47 2.62e-20 Blood protein levels; LIHC cis rs1801251 0.727 rs13029336 chr2:233569935 A/G cg25237894 chr2:233734115 C2orf82 -0.41 -7.95 -0.39 2.72e-14 Coronary artery disease; LIHC cis rs1371867 0.846 rs1788167 chr8:101319996 C/T cg06002616 chr8:101225028 SPAG1 -0.35 -5.91 -0.3 8.14e-9 Atrioventricular conduction; LIHC cis rs8177179 0.565 rs4355280 chr3:133468425 A/G cg16262614 chr3:133464971 TF 0.32 7.01 0.35 1.3e-11 Iron status biomarkers (transferrin levels); LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg22963979 chr7:1858916 MAD1L1 -0.44 -6.89 -0.35 2.66e-11 Bipolar disorder and schizophrenia; LIHC cis rs11112613 0.713 rs12321309 chr12:105943263 T/G cg03607813 chr12:105948248 NA 0.62 11.58 0.53 2.19e-26 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs6570726 0.846 rs372904 chr6:145887425 T/C cg23711669 chr6:146136114 FBXO30 0.65 11.6 0.53 1.83e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7762018 0.891 rs3088346 chr6:170149793 T/C cg13891659 chr6:170190454 C6orf122;C6orf208 0.51 6.28 0.32 1e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11245387 0.633 rs2086945 chr10:126543993 C/T cg08799069 chr10:126477246 METTL10 0.41 6.59 0.34 1.62e-10 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs1728785 0.681 rs4783647 chr16:68558048 G/A cg02972257 chr16:68554789 NA 0.59 6.35 0.32 6.99e-10 Ulcerative colitis; LIHC trans rs3808502 0.527 rs2736374 chr8:11113828 A/G cg09094615 chr8:17779997 PCM1 0.47 6.33 0.32 7.81e-10 Neuroticism; LIHC cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg00166722 chr3:10149974 C3orf24 -0.54 -6.32 -0.32 8.33e-10 Alzheimer's disease; LIHC cis rs4927850 1.000 rs6799572 chr3:195740408 C/T cg12923728 chr3:195709715 SDHAP1 -0.72 -9.99 -0.48 8.79e-21 Pancreatic cancer; LIHC cis rs801193 0.569 rs13226966 chr7:66233623 A/G cg18252515 chr7:66147081 NA -0.46 -6.77 -0.34 5.58e-11 Aortic root size; LIHC cis rs10876993 0.855 rs1678520 chr12:58049319 C/G cg04478727 chr12:58166393 METTL1;FAM119B -0.48 -6.76 -0.34 5.99e-11 Celiac disease or Rheumatoid arthritis; LIHC cis rs1577917 1.000 rs12663651 chr6:86701655 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.38 -0.33 5.85e-10 Response to antipsychotic treatment; LIHC cis rs9303401 0.659 rs12946852 chr17:57013337 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.28 0.58 9.81e-33 Cognitive test performance; LIHC cis rs7408868 1.000 rs7250232 chr19:15277199 C/T cg14696996 chr19:15285081 NOTCH3 0.51 6.91 0.35 2.44e-11 Pulse pressure; LIHC cis rs72480748 0.509 rs3865457 chr19:41398969 C/T cg09508736 chr19:41385865 CYP2A7 -0.45 -7.59 -0.38 2.97e-13 Post bronchodilator FEV1;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); LIHC cis rs10911232 0.524 rs10737238 chr1:183025303 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.68 0.5 3.67e-23 Hypertriglyceridemia; LIHC cis rs875971 0.862 rs778686 chr7:65835910 C/T cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs55665837 1.000 rs12295723 chr11:14450201 T/C cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs2072499 0.898 rs2736609 chr1:156202640 C/T cg24450063 chr1:156163899 SLC25A44 0.71 11.84 0.54 2.5e-27 Testicular germ cell tumor; LIHC cis rs6121246 0.529 rs6058196 chr20:30194714 A/T cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs17376456 0.825 rs6877030 chr5:93201841 C/A cg25358565 chr5:93447407 FAM172A 1.08 9.74 0.47 5.89e-20 Diabetic retinopathy; LIHC cis rs1728785 1.000 rs1728765 chr16:68589433 G/A cg02972257 chr16:68554789 NA -0.53 -6.15 -0.32 2.19e-9 Ulcerative colitis; LIHC cis rs929354 0.629 rs6950739 chr7:156982450 T/C cg17757837 chr7:157058334 UBE3C 0.74 11.99 0.54 6.58e-28 Body mass index; LIHC cis rs13191362 1.000 rs7769686 chr6:163199467 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.81 6.71 0.34 8.15e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2204008 0.837 rs11180549 chr12:38236950 A/G cg13010199 chr12:38710504 ALG10B 0.5 5.85 0.3 1.14e-8 Bladder cancer; LIHC cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg15691649 chr6:25882328 NA -0.54 -7.75 -0.39 1.07e-13 Blood metabolite levels; LIHC cis rs6120849 0.615 rs11167248 chr20:33538721 G/T cg24642439 chr20:33292090 TP53INP2 0.67 7.78 0.39 8.77e-14 Protein C levels; LIHC cis rs35110281 0.782 rs6518309 chr21:45047992 C/A cg01579765 chr21:45077557 HSF2BP -0.34 -6.13 -0.31 2.4e-9 Mean corpuscular volume; LIHC cis rs875971 0.545 rs1796226 chr7:66087710 C/T cg11764359 chr7:65958608 NA 0.61 8.73 0.43 1.12e-16 Aortic root size; LIHC cis rs28489187 0.706 rs2268667 chr1:85793746 A/G cg16011679 chr1:85725395 C1orf52 -0.46 -5.94 -0.31 7.01e-9 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs7481584 0.603 rs399467 chr11:3072348 G/A cg25174290 chr11:3078921 CARS -0.42 -6.21 -0.32 1.54e-9 Calcium levels; LIHC cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -11.15 -0.52 7.67e-25 Platelet count; LIHC trans rs7714584 1.000 rs114244137 chr5:150264753 C/A cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg16497277 chr3:49208875 KLHDC8B -0.51 -6.41 -0.33 4.72e-10 Menarche (age at onset); LIHC cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 9.3 0.45 1.69e-18 Platelet count; LIHC cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg23758822 chr17:41437982 NA 0.92 17.05 0.68 1.3e-47 Menopause (age at onset); LIHC cis rs2228479 0.717 rs12917681 chr16:89810941 C/A cg06558623 chr16:89946397 TCF25 0.82 11.52 0.53 3.71e-26 Skin colour saturation; LIHC cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.56 -7.93 -0.39 3.19e-14 Lymphocyte counts; LIHC cis rs7551222 0.752 rs10793767 chr1:204549564 A/C cg20240347 chr1:204465584 NA -0.33 -6.73 -0.34 7.01e-11 Schizophrenia; LIHC cis rs6783573 1.000 rs12185926 chr3:46602999 C/G cg21489266 chr3:46619131 LRRC2;TDGF1 -0.41 -6.23 -0.32 1.35e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg07636037 chr3:49044803 WDR6 0.76 12.95 0.57 1.69e-31 Menarche (age at onset); LIHC cis rs7208859 0.623 rs73267858 chr17:29059737 A/G cg14067834 chr17:29058358 SUZ12P 0.68 6.79 0.34 5.1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7772486 0.692 rs2265915 chr6:146194332 A/T cg23711669 chr6:146136114 FBXO30 0.73 13.14 0.58 3.29e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs3820068 0.559 rs6675334 chr1:15923580 A/T cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.01e-9 Systolic blood pressure; LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg02290350 chr8:58132656 NA 0.49 10.45 0.49 2.26e-22 Developmental language disorder (linguistic errors); LIHC cis rs7927771 0.965 rs35184771 chr11:47475189 G/T cg20135002 chr11:47629003 NA -0.57 -10.03 -0.48 6.14e-21 Subjective well-being; LIHC cis rs11098499 0.754 rs10006259 chr4:120242145 C/T cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs736408 0.561 rs2276815 chr3:52853747 C/G cg18404041 chr3:52824283 ITIH1 -0.43 -6.25 -0.32 1.22e-9 Bipolar disorder; LIHC cis rs10256972 0.521 rs7811577 chr7:1102829 C/G cg16145915 chr7:1198662 ZFAND2A -0.26 -5.92 -0.3 7.79e-9 Longevity;Endometriosis; LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg13903179 chr13:21900392 NA 0.37 6.32 0.32 8.25e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9457247 0.765 rs9457249 chr6:167426438 A/G cg12798992 chr6:167411361 FGFR1OP 0.49 7.54 0.38 4.33e-13 Crohn's disease; LIHC cis rs4906332 1.000 rs4900574 chr14:103879024 G/A cg04998671 chr14:104000505 TRMT61A 0.43 6.11 0.31 2.77e-9 Coronary artery disease; LIHC cis rs6860806 1.000 rs6860806 chr5:131640536 C/T cg24060327 chr5:131705240 SLC22A5 0.5 6.79 0.34 4.91e-11 Breast cancer; LIHC cis rs11711311 0.712 rs4682139 chr3:113331859 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.36 -6.3 -0.32 9.1e-10 IgG glycosylation; LIHC cis rs9309473 0.948 rs7566385 chr2:73756817 G/T cg20560298 chr2:73613845 ALMS1 -0.55 -6.95 -0.35 1.87e-11 Metabolite levels; LIHC cis rs7412746 0.611 rs111905669 chr1:150777565 T/C cg18016565 chr1:150552671 MCL1 0.53 10.02 0.48 6.73e-21 Melanoma; LIHC cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC trans rs61931739 0.500 rs11053236 chr12:34507962 C/G cg26384229 chr12:38710491 ALG10B 0.79 9.79 0.47 4.2e-20 Morning vs. evening chronotype; LIHC cis rs1401999 0.898 rs4148564 chr3:183725982 C/T cg20387954 chr3:183756860 HTR3D 0.27 5.85 0.3 1.13e-8 Anterior chamber depth; LIHC trans rs2727020 0.590 rs7949936 chr11:49378902 G/A cg03929089 chr4:120376271 NA -0.67 -9.53 -0.46 3.11e-19 Coronary artery disease; LIHC cis rs2806561 0.929 rs6694445 chr1:23540428 A/G cg19743168 chr1:23544995 NA 0.4 7.56 0.38 3.82e-13 Height; LIHC cis rs57221529 0.825 rs7443550 chr5:578404 G/T cg09021430 chr5:549028 NA -0.45 -8.73 -0.43 1.14e-16 Lung disease severity in cystic fibrosis; LIHC cis rs7129220 0.588 rs61878585 chr11:10101987 C/T cg01453529 chr11:10209919 SBF2 -0.39 -6.97 -0.35 1.62e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs11628318 0.588 rs12185065 chr14:103074636 A/C cg23461800 chr14:103021989 NA 0.4 6.12 0.31 2.54e-9 Platelet count; LIHC trans rs116095464 0.558 rs6555052 chr5:224268 G/A cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs9733 0.818 rs6694531 chr1:150683512 C/A cg18016565 chr1:150552671 MCL1 -0.5 -10.32 -0.49 6.68e-22 Tonsillectomy; LIHC cis rs7098414 0.511 rs7071752 chr10:82159539 C/A cg01528321 chr10:82214614 TSPAN14 0.44 6.61 0.34 1.51e-10 Post bronchodilator FEV1; LIHC trans rs2073499 0.935 rs57842657 chr3:50227787 T/A cg21659725 chr3:3221576 CRBN 0.6 6.64 0.34 1.24e-10 Schizophrenia; LIHC cis rs9399135 0.838 rs4896126 chr6:135342786 C/A cg22676075 chr6:135203613 NA 0.4 6.41 0.33 4.74e-10 Red blood cell count; LIHC cis rs10876993 0.890 rs774888 chr12:58036506 A/G cg18357645 chr12:58087776 OS9 0.49 8.09 0.4 1.06e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs2153535 0.562 rs9379211 chr6:8463927 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs3096299 0.967 rs28689480 chr16:89460093 T/C cg06640241 chr16:89574553 SPG7 0.66 10.62 0.5 5.89e-23 Multiple myeloma (IgH translocation); LIHC cis rs11758351 1.000 rs80095925 chr6:26184942 C/T cg03854865 chr6:26224070 HIST1H3E 0.71 7.81 0.39 7.07e-14 Gout;Renal underexcretion gout; LIHC cis rs9790314 0.846 rs899275 chr3:161042104 T/C cg03342759 chr3:160939853 NMD3 -0.79 -12.87 -0.57 3.65e-31 Morning vs. evening chronotype; LIHC cis rs11577318 0.579 rs11247934 chr1:26695758 A/T cg18121669 chr1:26560928 CCDC21 -0.49 -7.24 -0.36 3.02e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs4474465 0.850 rs11237537 chr11:78248397 C/T cg27205649 chr11:78285834 NARS2 -0.44 -6.88 -0.35 2.83e-11 Alzheimer's disease (survival time); LIHC cis rs1707322 1.000 rs1707322 chr1:46505147 C/T cg06784218 chr1:46089804 CCDC17 0.37 6.75 0.34 6.21e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg11644478 chr21:40555479 PSMG1 -0.45 -6.88 -0.35 2.9100000000000002e-11 Cognitive function; LIHC cis rs240764 0.853 rs10457808 chr6:100979506 A/T cg09795085 chr6:101329169 ASCC3 -0.44 -6.14 -0.32 2.27e-9 Neuroticism; LIHC cis rs875971 0.508 rs10258739 chr7:66062935 A/T cg14393609 chr7:65229607 NA -0.35 -5.77 -0.3 1.76e-8 Aortic root size; LIHC cis rs9325144 0.555 rs6582607 chr12:38717678 T/C cg26384229 chr12:38710491 ALG10B -0.55 -7.59 -0.38 3.1e-13 Morning vs. evening chronotype; LIHC cis rs41271473 0.526 rs942853 chr1:228730949 G/T cg10167378 chr1:228756711 NA 0.67 6.78 0.34 5.26e-11 Chronic lymphocytic leukemia; LIHC cis rs1707322 1.000 rs10789485 chr1:46407308 C/T cg06784218 chr1:46089804 CCDC17 0.37 6.65 0.34 1.14e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6502050 0.604 rs9897355 chr17:80078095 G/A cg13198984 chr17:80129470 CCDC57 -0.33 -5.83 -0.3 1.26e-8 Life satisfaction; LIHC cis rs1003719 0.788 rs9977314 chr21:38471963 G/T cg10648535 chr21:38446584 PIGP;TTC3 0.76 11.7 0.53 7.91e-27 Eye color traits; LIHC trans rs7615952 0.866 rs13063119 chr3:125643847 G/A cg07211511 chr3:129823064 LOC729375 -0.86 -10.74 -0.5 2.22e-23 Blood pressure (smoking interaction); LIHC cis rs6754311 0.512 rs12998387 chr2:136507039 A/G cg17750252 chr2:136567154 LCT 0.33 5.76 0.3 1.87e-8 Mosquito bite size; LIHC cis rs4808199 0.948 rs12982276 chr19:19459800 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.54 7.99 0.4 2.12e-14 Nonalcoholic fatty liver disease; LIHC cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg00166722 chr3:10149974 C3orf24 0.47 5.86 0.3 1.12e-8 Alzheimer's disease; LIHC cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg17554472 chr22:41940697 POLR3H -0.53 -5.86 -0.3 1.08e-8 Vitiligo; LIHC cis rs1801251 1.000 rs2100053 chr2:233719516 G/T cg08000102 chr2:233561755 GIGYF2 -0.76 -11.52 -0.53 3.72e-26 Coronary artery disease; LIHC cis rs17102423 0.594 rs1124751 chr14:65567601 C/A cg16583315 chr14:65563665 MAX -0.4 -8.17 -0.4 5.92e-15 Obesity-related traits; LIHC cis rs1034435 0.755 rs9615336 chr22:48893090 G/C cg05992904 chr22:48892994 FAM19A5 -0.53 -10.87 -0.51 7.81e-24 Late-onset Alzheimer's disease; LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.73 10.78 0.5 1.63e-23 Lymphocyte counts; LIHC cis rs4919694 1.000 rs3740394 chr10:104634474 A/G cg04362960 chr10:104952993 NT5C2 1.0 8.02 0.4 1.66e-14 Arsenic metabolism; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg05834845 chr3:195489306 MUC4 -0.64 -9.69 -0.46 9.09e-20 Lung disease severity in cystic fibrosis; LIHC cis rs6938 0.534 rs4886636 chr15:75196176 G/A cg14664628 chr15:75095509 CSK -0.47 -6.56 -0.33 2.04e-10 Breast cancer; LIHC cis rs9300255 0.543 rs655293 chr12:123528405 G/A cg00376283 chr12:123451042 ABCB9 0.64 8.69 0.43 1.5e-16 Neutrophil percentage of white cells; LIHC cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg20295408 chr7:1910781 MAD1L1 -0.42 -6.04 -0.31 4.08e-9 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.562 rs6901765 chr6:8455436 A/T cg07606381 chr6:8435919 SLC35B3 0.8 12.0 0.54 6.16e-28 Motion sickness; LIHC cis rs507080 0.961 rs520543 chr11:118538157 G/A cg04173919 chr11:118528438 PHLDB1 0.33 6.2 0.32 1.67e-9 Serum metabolite levels; LIHC cis rs60871478 1.000 rs62432861 chr7:807649 G/A cg27478167 chr7:817139 HEATR2 -0.41 -5.82 -0.3 1.38e-8 Cerebrospinal P-tau181p levels; LIHC cis rs864643 0.891 rs661366 chr3:39561348 G/T cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs8103278 0.860 rs11669073 chr19:46324880 C/T cg02376097 chr19:46275166 DMPK -0.45 -6.92 -0.35 2.23e-11 Coronary artery disease; LIHC cis rs17401966 0.931 rs10864448 chr1:10277497 A/T cg19773385 chr1:10388646 KIF1B -0.38 -6.71 -0.34 8.26e-11 Hepatocellular carcinoma; LIHC cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg09455208 chr3:40491958 NA 0.34 6.97 0.35 1.64e-11 Renal cell carcinoma; LIHC cis rs798554 0.704 rs2527684 chr7:2825922 G/T cg13628971 chr7:2884303 GNA12 0.38 6.06 0.31 3.6e-9 Height; LIHC cis rs4795419 1 rs4795419 chr17:38166003 G/A cg17467752 chr17:38218738 THRA 0.76 13.99 0.6 1.82e-35 Monocyte percentage of white cells; LIHC cis rs4742903 0.584 rs10217250 chr9:106911633 A/T cg14250997 chr9:106856677 SMC2 0.38 6.71 0.34 7.95e-11 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs13108904 0.901 rs66987549 chr4:1272617 C/T cg13395646 chr4:1353034 KIAA1530 -0.48 -7.48 -0.37 6.37e-13 Obesity-related traits; LIHC cis rs969413 0.624 rs9914093 chr17:79260653 C/G cg05353290 chr17:79219831 SLC38A10 0.39 5.93 0.31 7.42e-9 Frontotemporal dementia; LIHC cis rs3015497 0.789 rs7147956 chr14:51142605 G/A cg09863266 chr14:51125203 SAV1 -0.39 -6.21 -0.32 1.52e-9 Mean platelet volume; LIHC cis rs7408868 1.000 rs10416389 chr19:15278674 G/C cg14696996 chr19:15285081 NOTCH3 0.54 7.08 0.36 8.26e-12 Pulse pressure; LIHC cis rs28595532 0.748 rs66615663 chr4:119336701 C/T cg21605333 chr4:119757512 SEC24D 0.97 8.11 0.4 9.41e-15 Cannabis dependence symptom count; LIHC cis rs9916302 0.653 rs11657058 chr17:37699378 T/G cg07936489 chr17:37558343 FBXL20 -0.84 -11.92 -0.54 1.24e-27 Glomerular filtration rate (creatinine); LIHC cis rs986417 1.000 rs1272688 chr14:60920718 T/C cg27398547 chr14:60952738 C14orf39 -0.81 -9.56 -0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs2384207 0.789 rs7137793 chr12:113658124 T/G cg22376712 chr12:113623594 C12orf52;DDX54 0.51 6.19 0.32 1.71e-9 Response to fenofibrate (adiponectin levels); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27438756 chr1:74663921 TNNI3K;FPGT;LRRIQ3 -0.55 -7.8 -0.39 7.78e-14 Pancreatic cancer; LIHC cis rs2072499 1.000 rs2540173 chr1:156188214 A/G cg24450063 chr1:156163899 SLC25A44 1.07 19.01 0.72 1.71e-55 Testicular germ cell tumor; LIHC cis rs2842992 0.789 rs10945635 chr6:160214487 C/A cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.72 0.57 1.32e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs12893668 0.703 rs7140568 chr14:104041374 C/T cg19000871 chr14:103996768 TRMT61A -0.44 -7.16 -0.36 5.12e-12 Reticulocyte count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26794364 chr3:9691143 MTMR14 0.44 6.45 0.33 3.77e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10197940 0.624 rs10497082 chr2:152355258 T/C cg06191203 chr2:152266755 RIF1 -0.44 -7.49 -0.38 5.83e-13 Lung cancer; LIHC cis rs7903847 0.642 rs11189191 chr10:99148796 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.27 -0.32 1.07e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs472402 0.580 rs8192186 chr5:6652009 G/A cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.46 -5.73 -0.3 2.17e-8 Response to amphetamines; LIHC trans rs920065 0.713 rs13323468 chr3:5934638 G/T cg25753567 chr19:1420366 DAZAP1 -0.58 -6.16 -0.32 2.08e-9 Excessive daytime sleepiness; LIHC cis rs12135062 0.755 rs1553287 chr1:3101277 G/A cg21609526 chr1:3105151 PRDM16 -0.3 -6.67 -0.34 1.04e-10 Migraine; LIHC cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg00166722 chr3:10149974 C3orf24 0.48 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC cis rs797680 0.856 rs6685271 chr1:93634590 C/A cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.03 -0.31 4.16e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs80282103 0.867 rs3793781 chr10:1081293 G/T cg18964960 chr10:1102726 WDR37 0.67 6.29 0.32 9.47e-10 Glomerular filtration rate (creatinine); LIHC cis rs797680 0.856 rs637646 chr1:93716383 A/C cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.89 0.3 9.29e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg05896524 chr21:47604654 C21orf56 0.45 6.78 0.34 5.34e-11 Testicular germ cell tumor; LIHC cis rs10792665 0.649 rs948182 chr11:82746231 C/T cg24227371 chr11:82718527 RAB30 -0.39 -9.27 -0.45 2.16e-18 Obesity-related traits; LIHC cis rs12701220 0.553 rs7782024 chr7:1157502 G/T cg26240231 chr7:1148101 C7orf50 -0.39 -5.94 -0.31 6.84e-9 Bronchopulmonary dysplasia; LIHC cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg16606324 chr3:10149918 C3orf24 0.52 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs8067354 0.645 rs9910518 chr17:57812067 T/C cg02344993 chr17:57696989 CLTC 0.7 11.84 0.54 2.48e-27 Hemoglobin concentration; LIHC cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.49 -6.86 -0.35 3.26e-11 Prostate cancer; LIHC cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg21782813 chr7:2030301 MAD1L1 0.49 8.07 0.4 1.22e-14 Bipolar disorder and schizophrenia; LIHC cis rs2629540 0.765 rs11245387 chr10:126537825 C/T cg08799069 chr10:126477246 METTL10 -0.49 -8.26 -0.41 3.17e-15 Cocaine dependence; LIHC cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 7.81 0.39 6.87e-14 Schizophrenia; LIHC cis rs6952808 0.707 rs13244345 chr7:1973004 A/G cg14004847 chr7:1930337 MAD1L1 -0.52 -7.59 -0.38 3.05e-13 Bipolar disorder and schizophrenia; LIHC cis rs6674176 0.597 rs12127737 chr1:44402565 G/A cg12908607 chr1:44402522 ARTN -0.52 -8.87 -0.43 3.99e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6977660 0.714 rs10244210 chr7:19823972 T/C cg07541023 chr7:19748670 TWISTNB 0.42 6.13 0.31 2.42e-9 Thyroid stimulating hormone; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg09033563 chr22:24373618 LOC391322 -0.51 -7.11 -0.36 6.68e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7927771 0.864 rs755555 chr11:47431966 C/T cg20135002 chr11:47629003 NA -0.56 -9.24 -0.45 2.72e-18 Subjective well-being; LIHC cis rs5769765 1.000 rs5769760 chr22:50259696 A/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg07061783 chr6:25882402 NA -0.46 -6.41 -0.33 4.91e-10 Blood metabolite levels; LIHC cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg09323728 chr8:95962352 TP53INP1 -0.31 -6.81 -0.35 4.38e-11 Type 2 diabetes; LIHC cis rs1005277 0.541 rs2472177 chr10:38384015 T/G cg03665457 chr10:38645376 HSD17B7P2 -0.39 -5.77 -0.3 1.81e-8 Extrinsic epigenetic age acceleration; LIHC cis rs6062302 0.522 rs6090476 chr20:62248001 G/A cg09650180 chr20:62225654 GMEB2 -0.38 -6.05 -0.31 3.87e-9 Glioblastoma; LIHC cis rs7927592 0.672 rs10501398 chr11:68331715 C/G cg16797656 chr11:68205561 LRP5 -0.51 -9.06 -0.44 1.01e-17 Total body bone mineral density; LIHC cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg26818010 chr10:134567672 INPP5A -0.72 -9.07 -0.44 9.56e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9640161 0.830 rs11768108 chr7:150064150 C/T cg21361702 chr7:150065534 REPIN1 0.54 7.51 0.38 5.12e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs10089 1.000 rs4836368 chr5:127486330 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.49 0.33 2.93e-10 Ileal carcinoids; LIHC cis rs9303401 0.538 rs2240259 chr17:56458129 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.88 11.52 0.53 3.75e-26 Cognitive test performance; LIHC cis rs9368481 0.761 rs4358615 chr6:26998567 A/G cg12292205 chr6:26970375 C6orf41 0.47 8.17 0.4 6.14e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs539096 0.540 rs3011219 chr1:44306120 A/G cg12908607 chr1:44402522 ARTN -0.45 -7.68 -0.38 1.68e-13 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.554 rs2272121 chr3:10047680 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs16958440 0.867 rs78854354 chr18:44666924 C/G cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs7572733 0.534 rs1401095 chr2:198779867 C/T cg10820045 chr2:198174542 NA -0.47 -7.2 -0.36 3.92e-12 Dermatomyositis; LIHC cis rs1023500 0.551 rs2854837 chr22:42458481 G/A cg00645731 chr22:42541494 CYP2D7P1 0.4 6.23 0.32 1.34e-9 Schizophrenia; LIHC cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg00815214 chr21:47717953 NA 0.36 5.86 0.3 1.07e-8 Testicular germ cell tumor; LIHC cis rs703842 1.000 rs2072052 chr12:58146719 A/C cg04478727 chr12:58166393 METTL1;FAM119B 0.85 13.13 0.58 3.7e-32 Multiple sclerosis; LIHC cis rs17401966 0.931 rs12753426 chr1:10372110 T/C cg19773385 chr1:10388646 KIF1B -0.41 -7.45 -0.37 7.79e-13 Hepatocellular carcinoma; LIHC trans rs1144333 0.655 rs58722308 chr1:76423525 A/G cg10154597 chr10:134910271 GPR123 0.31 6.11 0.31 2.69e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs11800820 0.555 rs12565947 chr1:246650225 T/C cg16700716 chr1:246684329 NA -0.43 -7.58 -0.38 3.2e-13 Obesity-related traits; LIHC cis rs17685 0.712 rs869805 chr7:75688596 C/T cg01364799 chr7:75623366 TMEM120A -0.51 -7.81 -0.39 6.99e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6960043 1.000 rs6980437 chr7:15054916 T/G cg19272540 chr7:15055459 NA -0.22 -6.12 -0.31 2.57e-9 Type 2 diabetes; LIHC cis rs798766 1.000 rs7682402 chr4:1743343 G/A cg21231739 chr4:1642635 FAM53A -0.38 -5.98 -0.31 5.67e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs17376456 0.825 rs7715562 chr5:93222034 C/T cg25358565 chr5:93447407 FAM172A -1.05 -9.67 -0.46 1.03e-19 Diabetic retinopathy; LIHC cis rs7937890 0.904 rs11023169 chr11:14290985 C/A cg02251663 chr11:14281053 SPON1 0.45 6.2 0.32 1.59e-9 Mitochondrial DNA levels; LIHC cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs12497850 1.000 rs4858828 chr3:48724811 C/T cg07636037 chr3:49044803 WDR6 0.79 13.36 0.59 4.81e-33 Parkinson's disease; LIHC cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.58 0.34 1.79e-10 Bipolar disorder; LIHC trans rs9354352 1.000 rs9354352 chr6:66696272 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.6 9.66 0.46 1.08e-19 Initial pursuit acceleration in psychotic disorders; LIHC cis rs801193 1.000 rs7789184 chr7:66210195 A/T cg11764359 chr7:65958608 NA 0.71 10.58 0.5 8.11e-23 Aortic root size; LIHC cis rs1395 0.922 rs13404446 chr2:27519254 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -5.84 -0.3 1.19e-8 Blood metabolite levels; LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg19318889 chr4:1322082 MAEA 0.63 10.1 0.48 3.77e-21 Longevity; LIHC cis rs2766692 1.000 rs2766690 chr14:100682154 A/G cg14866419 chr14:100704911 YY1 -0.44 -5.99 -0.31 5.38e-9 Electroencephalographic traits in alcoholism; LIHC cis rs2439831 0.681 rs484029 chr15:43619560 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 17.13 0.68 6.05e-48 Lung cancer in ever smokers; LIHC cis rs72627123 0.867 rs73303135 chr14:74495090 C/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.65 0.46 1.18e-19 Morning vs. evening chronotype; LIHC cis rs881375 0.933 rs7859805 chr9:123664123 A/G cg14580859 chr9:123691850 NA 0.39 6.83 0.35 3.96e-11 Rheumatoid arthritis; LIHC cis rs6545883 0.929 rs2256615 chr2:61679894 C/G cg15711740 chr2:61764176 XPO1 -0.43 -5.99 -0.31 5.35e-9 Tuberculosis; LIHC cis rs782590 0.869 rs782599 chr2:55847423 C/T cg18811423 chr2:55921094 PNPT1 0.95 14.93 0.63 3.78e-39 Metabolic syndrome; LIHC cis rs12908161 0.960 rs34452033 chr15:85221993 A/G cg03959625 chr15:84868606 LOC388152 0.43 6.0 0.31 5.03e-9 Schizophrenia; LIHC cis rs12477438 0.765 rs4851183 chr2:99629149 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.26 -0.41 3.31e-15 Chronic sinus infection; LIHC cis rs1707322 1.000 rs1707338 chr1:46511981 T/G cg03146154 chr1:46216737 IPP -0.45 -7.4 -0.37 1.05e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02184643 chr11:10879647 ZBED5 -0.48 -6.23 -0.32 1.34e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs1814175 0.817 rs28502006 chr11:50049930 T/C cg03929089 chr4:120376271 NA -0.89 -18.71 -0.71 2.82e-54 Height; LIHC cis rs12931792 0.682 rs12373113 chr16:30187513 C/T cg17640201 chr16:30407289 ZNF48 0.39 6.45 0.33 3.84e-10 Tonsillectomy; LIHC cis rs6782228 0.585 rs2712392 chr3:128424257 G/A cg16766828 chr3:128327626 NA -0.36 -5.79 -0.3 1.55e-8 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs12249377 0.519 rs66650915 chr10:92592468 T/C cg14313238 chr10:92632228 RPP30 0.38 6.37 0.33 5.94e-10 White matter microstructure (global fractional anisotropy); LIHC trans rs7922314 0.764 rs12220702 chr10:64628704 G/A cg06816054 chr8:27695695 PBK 0.56 6.14 0.32 2.24e-9 Cutaneous psoriasis; LIHC cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg08677398 chr8:58056175 NA 0.4 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs12497850 0.931 rs13064784 chr3:49135961 C/G cg07636037 chr3:49044803 WDR6 0.9 15.72 0.65 2.67e-42 Parkinson's disease; LIHC cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.55 0.38 3.99e-13 Electroencephalogram traits; LIHC cis rs8017423 0.935 rs716122 chr14:90792313 A/C cg04374321 chr14:90722782 PSMC1 -0.72 -13.22 -0.58 1.56e-32 Mortality in heart failure; LIHC cis rs7772486 0.743 rs111332144 chr6:146056681 C/T cg23711669 chr6:146136114 FBXO30 -0.49 -8.59 -0.42 3.08e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs9733 0.687 rs12410050 chr1:150857141 A/G cg17724175 chr1:150552817 MCL1 -0.36 -6.82 -0.35 4.1e-11 Tonsillectomy; LIHC cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg00343986 chr7:65444356 GUSB -0.42 -5.92 -0.3 7.93e-9 Aortic root size; LIHC cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg19723775 chr5:179050963 HNRNPH1 0.42 6.54 0.33 2.25e-10 Lung cancer; LIHC cis rs1670533 1.000 rs2045065 chr4:1052488 A/G cg27284194 chr4:1044797 NA 0.59 8.67 0.42 1.71e-16 Recombination rate (females); LIHC cis rs875971 0.545 rs73376401 chr7:65639828 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.43 0.37 8.68e-13 Aortic root size; LIHC cis rs7523273 0.606 rs2724391 chr1:207953244 T/C cg22525895 chr1:207977042 MIR29B2 0.61 9.95 0.47 1.21e-20 Schizophrenia; LIHC cis rs17376456 0.877 rs13170509 chr5:93378564 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg02993280 chr1:107599747 PRMT6 0.59 9.32 0.45 1.46e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9911578 1.000 rs2333332 chr17:56631054 A/G cg05425664 chr17:57184151 TRIM37 0.58 8.64 0.42 2.17e-16 Intelligence (multi-trait analysis); LIHC cis rs1008375 0.932 rs7697329 chr4:17657853 C/A cg02297831 chr4:17616191 MED28 0.43 6.02 0.31 4.46e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2122469 0.655 rs17603934 chr8:20576344 A/G cg23188819 chr8:21947203 FAM160B2 -0.57 -6.04 -0.31 3.93e-9 Serum tamsulosin hydrochloride concentration; LIHC trans rs1814175 0.588 rs4076322 chr11:49745094 G/A cg03929089 chr4:120376271 NA -0.86 -16.84 -0.67 9.09e-47 Height; LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.15 -0.32 2.2e-9 Total body bone mineral density; LIHC cis rs6089829 0.888 rs4809471 chr20:61684287 G/A cg03213289 chr20:61660250 NA 0.53 9.18 0.44 4.2e-18 Prostate cancer (SNP x SNP interaction); LIHC trans rs5756813 1.000 rs5756813 chr22:38175477 A/C cg19894588 chr14:64061835 NA -0.62 -9.63 -0.46 1.4e-19 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7772486 0.875 rs2748497 chr6:146319417 C/T cg23711669 chr6:146136114 FBXO30 0.58 10.07 0.48 4.65e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs1555399 1.000 rs1555398 chr14:67984373 C/G cg16224230 chr14:67978224 TMEM229B -0.24 -5.81 -0.3 1.46e-8 Parkinson's disease; LIHC cis rs986417 0.748 rs10133403 chr14:60945298 C/T cg27398547 chr14:60952738 C14orf39 0.81 9.39 0.45 8.69e-19 Gut microbiota (bacterial taxa); LIHC cis rs11212260 0.655 rs11212198 chr11:107263130 T/C cg25435332 chr11:107328525 CWF19L2 0.8 8.44 0.42 9.23e-16 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15392845 chr14:73360933 DPF3 0.42 6.36 0.33 6.28e-10 Cognitive function; LIHC cis rs7551222 0.749 rs11240761 chr1:204566700 C/A cg20240347 chr1:204465584 NA -0.3 -6.2 -0.32 1.59e-9 Schizophrenia; LIHC cis rs367615 0.661 rs9326775 chr5:108836925 A/T cg17395555 chr5:108820864 NA 0.4 8.55 0.42 4.13e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs4563143 0.514 rs112540771 chr19:29316100 C/T cg04546413 chr19:29218101 NA 0.49 8.49 0.42 6.2e-16 Methadone dose in opioid dependence; LIHC cis rs4970988 0.527 rs12067556 chr1:150614535 G/A cg17724175 chr1:150552817 MCL1 0.55 11.39 0.52 1.05e-25 Urate levels; LIHC cis rs9393692 0.905 rs7747133 chr6:26293470 C/T cg05868516 chr6:26286170 HIST1H4H 0.41 6.22 0.32 1.47e-9 Educational attainment; LIHC cis rs2439831 0.867 rs2584702 chr15:43684914 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 16.14 0.66 5.71e-44 Lung cancer in ever smokers; LIHC cis rs9611519 0.780 rs3171692 chr22:41642212 C/T cg03806693 chr22:41940476 POLR3H -0.65 -7.54 -0.38 4.39e-13 Neuroticism; LIHC cis rs4820294 1.000 rs41280035 chr22:38054038 A/G cg10587741 chr22:38071170 LGALS1 0.68 11.72 0.54 6.64e-27 Fat distribution (HIV); LIHC cis rs11031096 0.655 rs35898891 chr11:4211112 G/C cg18678763 chr11:4115507 RRM1 -0.4 -5.87 -0.3 1.05e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1385374 0.858 rs11059930 chr12:129297860 T/C cg09035930 chr12:129282057 SLC15A4 -0.5 -5.95 -0.31 6.49e-9 Systemic lupus erythematosus; LIHC cis rs9517320 0.534 rs9554477 chr13:99160379 C/T cg07423050 chr13:99094983 FARP1 -0.45 -8.08 -0.4 1.09e-14 Longevity; LIHC trans rs9388451 0.626 rs1343115 chr6:126069817 C/G cg05039488 chr6:79577232 IRAK1BP1 -0.66 -10.88 -0.51 6.98e-24 Brugada syndrome; LIHC cis rs1401999 0.898 rs9876143 chr3:183731362 C/G cg01324343 chr3:183735012 ABCC5 0.77 12.68 0.57 1.88e-30 Anterior chamber depth; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07194495 chr7:148958859 ZNF783 0.4 7.0 0.35 1.38e-11 Cognitive function; LIHC cis rs7116495 0.609 rs1892920 chr11:71702431 A/G cg10381502 chr11:71823885 C11orf51 -1.0 -8.62 -0.42 2.6e-16 Severe influenza A (H1N1) infection; LIHC trans rs4714291 0.792 rs9471241 chr6:40080211 C/T cg02267698 chr19:7991119 CTXN1 -0.41 -6.91 -0.35 2.42e-11 Strep throat; LIHC cis rs2439831 0.702 rs2788 chr15:44064886 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.43 0.33 4.32e-10 Lung cancer in ever smokers; LIHC cis rs4638749 0.677 rs34449318 chr2:108827222 T/C cg06795125 chr2:108905320 SULT1C2 -0.31 -6.04 -0.31 3.92e-9 Blood pressure; LIHC cis rs7707921 0.522 rs4703537 chr5:81480371 C/T cg15871215 chr5:81402204 ATG10 0.6 8.19 0.41 5.18e-15 Breast cancer; LIHC cis rs7089973 0.604 rs7095816 chr10:116585109 T/C cg03647239 chr10:116582469 FAM160B1 0.46 6.64 0.34 1.21e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7615952 0.673 rs35001498 chr3:125628644 A/G cg05084668 chr3:125655381 ALG1L -0.8 -10.65 -0.5 4.69e-23 Blood pressure (smoking interaction); LIHC cis rs4727027 0.870 rs62507509 chr7:148795522 C/T cg23583168 chr7:148888333 NA -0.7 -9.69 -0.46 8.81e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg04751069 chr16:89787483 ZNF276;C16orf7 0.51 6.2 0.32 1.6e-9 Hepatitis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23679085 chr3:183892773 AP2M1 0.45 6.69 0.34 9.35e-11 Pancreatic cancer; LIHC cis rs11077998 0.967 rs12185229 chr17:80499065 G/C cg10255544 chr17:80519551 FOXK2 0.48 8.81 0.43 6.4e-17 Reticulocyte fraction of red cells; LIHC cis rs1577917 0.958 rs1591437 chr6:86525305 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -11.03 -0.51 2.07e-24 Response to antipsychotic treatment; LIHC trans rs11098499 0.604 rs2389882 chr4:120566733 A/C cg25214090 chr10:38739885 LOC399744 0.5 7.94 0.39 2.96e-14 Corneal astigmatism; LIHC cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg03452623 chr4:187889614 NA -0.35 -9.28 -0.45 2.03e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs4243830 0.850 rs3761927 chr1:6601773 T/C cg22792644 chr1:6614718 TAS1R1;NOL9 -0.95 -12.12 -0.55 2.25e-28 Body mass index; LIHC cis rs35110281 0.807 rs9976441 chr21:45046591 G/A cg04455712 chr21:45112962 RRP1B 0.45 7.79 0.39 8.14e-14 Mean corpuscular volume; LIHC cis rs7552404 1.000 rs11161511 chr1:76210477 A/G cg10523679 chr1:76189770 ACADM -0.6 -8.45 -0.42 8.31e-16 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22854549 chr19:5904785 VMAC;NDUFA11 0.53 7.01 0.35 1.25e-11 Lung function (FEV1/FVC); LIHC cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg21724239 chr8:58056113 NA 0.48 6.29 0.32 9.98e-10 Developmental language disorder (linguistic errors); LIHC cis rs1355223 0.583 rs1396881 chr11:34870506 G/T cg24088639 chr11:34937564 PDHX;APIP -0.39 -5.99 -0.31 5.17e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs3942852 0.774 rs10838812 chr11:48186924 T/C cg15704280 chr7:45808275 SEPT13 -0.59 -8.02 -0.4 1.65e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs12048904 0.512 rs932798 chr1:101249355 G/C cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.4 -5.87 -0.3 1.05e-8 Multiple sclerosis; LIHC cis rs611744 0.967 rs2212704 chr8:109198415 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs2279817 0.818 rs71644062 chr1:17980530 C/T cg21791023 chr1:18019539 ARHGEF10L -0.65 -7.11 -0.36 6.68e-12 Neuroticism; LIHC cis rs10857712 0.784 rs2265639 chr10:135221576 C/G cg01444801 chr10:135216882 MTG1 0.66 9.88 0.47 2.12e-20 Systemic lupus erythematosus; LIHC cis rs9896850 0.513 rs10445407 chr17:79261809 A/C cg08034816 chr17:79219380 SLC38A10 -0.37 -6.23 -0.32 1.36e-9 Frontotemporal dementia; LIHC cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC cis rs921968 0.643 rs471846 chr2:219432237 C/T cg18887096 chr2:219472410 PLCD4 0.36 6.33 0.32 7.86e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1008375 0.966 rs2315553 chr4:17627332 T/C cg02297831 chr4:17616191 MED28 0.5 7.83 0.39 6.24e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2243480 1.000 rs34702770 chr7:65344823 T/C cg10756647 chr7:56101905 PSPH 1.09 13.38 0.59 4.07e-33 Diabetic kidney disease; LIHC cis rs1185460 0.565 rs2276060 chr11:118919132 G/A cg23280166 chr11:118938394 VPS11 -0.43 -5.81 -0.3 1.44e-8 Coronary artery disease; LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg09455208 chr3:40491958 NA 0.4 7.83 0.39 6.01e-14 Renal cell carcinoma; LIHC cis rs2479724 0.935 rs7753507 chr6:41784094 C/T cg17623882 chr6:41773611 USP49 0.55 8.66 0.42 1.94e-16 Menarche (age at onset); LIHC cis rs798554 0.757 rs1182185 chr7:2872233 A/G cg19346786 chr7:2764209 NA -0.43 -6.13 -0.31 2.4e-9 Height; LIHC cis rs62458065 1.000 rs10275978 chr7:32466719 G/T cg06627557 chr7:32535165 LSM5;AVL9 -0.65 -7.43 -0.37 8.69e-13 Metabolite levels (HVA/MHPG ratio); LIHC cis rs2204008 0.775 rs12099736 chr12:38344111 C/G cg26384229 chr12:38710491 ALG10B 0.59 8.08 0.4 1.09e-14 Bladder cancer; LIHC cis rs12497850 0.863 rs4974084 chr3:48939080 G/A cg07636037 chr3:49044803 WDR6 0.92 16.29 0.66 1.43e-44 Parkinson's disease; LIHC cis rs600806 0.850 rs3879452 chr1:109929237 G/A cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.898 rs17462433 chr2:24012758 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs2279817 0.735 rs71644063 chr1:17987274 A/G cg21791023 chr1:18019539 ARHGEF10L -0.65 -7.22 -0.36 3.45e-12 Neuroticism; LIHC cis rs8180040 0.768 rs11915074 chr3:47309757 A/T cg27129171 chr3:47204927 SETD2 -0.56 -9.06 -0.44 1.06e-17 Colorectal cancer; LIHC cis rs2760061 0.626 rs596675 chr1:228117892 G/A cg02753203 chr1:228287806 NA -0.51 -8.13 -0.4 8.13e-15 Diastolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02037503 chr14:23540729 ACIN1 0.41 6.38 0.33 5.85e-10 Cognitive function; LIHC cis rs7615952 0.641 rs2365019 chr3:125808135 T/C cg05084668 chr3:125655381 ALG1L -0.39 -5.97 -0.31 5.98e-9 Blood pressure (smoking interaction); LIHC cis rs7845219 0.544 rs7015841 chr8:95920193 A/C cg13393036 chr8:95962371 TP53INP1 -0.32 -6.19 -0.32 1.69e-9 Type 2 diabetes; LIHC cis rs7188697 0.922 rs1549607 chr16:58583975 A/G cg02549819 chr16:58548995 SETD6 0.48 7.59 0.38 3.16e-13 QT interval; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg14536467 chr19:17412305 ABHD8 0.36 6.2 0.32 1.67e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs798766 1.000 rs798767 chr4:1734281 A/G cg21231739 chr4:1642635 FAM53A -0.38 -6.0 -0.31 4.9e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs11758351 0.866 rs75091077 chr6:26207546 A/C cg03785755 chr6:26196794 NA 0.5 5.88 0.3 9.89e-9 Gout;Renal underexcretion gout; LIHC cis rs10504229 0.871 rs16921952 chr8:58163317 A/T cg02290350 chr8:58132656 NA 0.39 8.4 0.41 1.19e-15 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg00166722 chr3:10149974 C3orf24 0.52 6.02 0.31 4.54e-9 Alzheimer's disease; LIHC cis rs61677309 1.000 rs12576947 chr11:118158055 T/C cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs896854 0.902 rs896852 chr8:95960886 G/T cg23172400 chr8:95962367 TP53INP1 -0.43 -10.27 -0.49 9.53e-22 Type 2 diabetes; LIHC cis rs55665837 1.000 rs12804549 chr11:14437758 A/T cg19336497 chr11:14380999 RRAS2 -0.44 -8.27 -0.41 2.98e-15 Vitamin D levels; LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg14159672 chr1:205819179 PM20D1 0.73 10.28 0.49 8.78e-22 Menarche (age at onset); LIHC trans rs9951602 0.512 rs1599635 chr18:76643819 G/A cg02800362 chr5:177631904 HNRNPAB 0.64 10.24 0.48 1.24e-21 Obesity-related traits; LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg24503407 chr1:205819492 PM20D1 0.71 10.17 0.48 2.1e-21 Menarche (age at onset); LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.4 0.8 7.17e-77 Prudent dietary pattern; LIHC cis rs17685 0.697 rs28689051 chr7:75763624 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.37 -6.03 -0.31 4.26e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg02290350 chr8:58132656 NA 0.47 8.77 0.43 8.27e-17 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.735 rs2808580 chr1:231509259 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs826838 0.616 rs9668847 chr12:38614669 C/T cg26384229 chr12:38710491 ALG10B 0.43 6.49 0.33 2.93e-10 Heart rate; LIHC trans rs2211698 1.000 rs58861465 chr21:35827067 C/T cg18044562 chr7:50468399 IKZF1 0.5 7.2 0.36 3.82e-12 Cancer; LIHC cis rs1577917 1.000 rs12199516 chr6:86726221 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.96 -0.35 1.71e-11 Response to antipsychotic treatment; LIHC cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg11644478 chr21:40555479 PSMG1 0.81 10.06 0.48 5.15e-21 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00920043 chr1:11333412 UBIAD1 0.39 6.43 0.33 4.2e-10 Cognitive function; LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg14671364 chr1:107599128 PRMT6 0.42 5.9 0.3 8.68e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1707322 1.000 rs7547284 chr1:46319565 C/G cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9486719 0.522 rs4839683 chr6:96851933 A/G cg06623918 chr6:96969491 KIAA0776 0.5 6.28 0.32 1.04e-9 Migraine;Coronary artery disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04305134 chr10:75173374 ANXA7 -0.48 -6.58 -0.34 1.78e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -11.33 -0.52 1.73e-25 Platelet count; LIHC cis rs9359856 0.564 rs10484885 chr6:90395016 A/G cg13799429 chr6:90582589 CASP8AP2 -0.64 -5.93 -0.31 7.52e-9 Bipolar disorder; LIHC cis rs11608355 0.545 rs61941585 chr12:109905222 C/T cg05360138 chr12:110035743 NA 0.95 10.52 0.49 1.35e-22 Neuroticism; LIHC cis rs3806843 0.966 rs6579965 chr5:140168811 T/G cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs3020736 0.500 rs6519306 chr22:42501217 T/C cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs4820294 0.770 rs7285699 chr22:38066556 A/C cg00292662 chr22:38071168 LGALS1 0.38 6.45 0.33 3.71e-10 Fat distribution (HIV); LIHC cis rs7582180 0.764 rs11693424 chr2:100925439 G/A cg14675211 chr2:100938903 LONRF2 0.51 8.05 0.4 1.42e-14 Intelligence (multi-trait analysis); LIHC cis rs6584283 0.846 rs11190135 chr10:101286848 A/G cg06854084 chr10:101292507 NKX2-3 -0.32 -5.86 -0.3 1.06e-8 Ulcerative colitis; LIHC cis rs1499280 1.000 rs2059202 chr5:52097183 A/G cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs3806843 0.750 rs2563285 chr5:140126137 T/C cg19875535 chr5:140030758 IK -0.37 -6.17 -0.32 1.9e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06056004 chr5:44809616 MRPS30 0.45 6.48 0.33 3.25e-10 Pancreatic cancer; LIHC cis rs7605378 0.752 rs769960 chr2:200710706 G/T cg23649088 chr2:200775458 C2orf69 -0.48 -6.57 -0.33 1.88e-10 Osteoporosis; LIHC cis rs2075371 0.829 rs10954442 chr7:134007587 A/G cg20476274 chr7:133979776 SLC35B4 -0.69 -9.14 -0.44 5.69e-18 Mean platelet volume; LIHC cis rs1005277 0.540 rs11011351 chr10:38030525 A/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.61 -0.46 1.65e-19 Extrinsic epigenetic age acceleration; LIHC cis rs11098499 0.657 rs71614442 chr4:120379346 C/T cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs1799949 1.000 rs8176318 chr17:41197274 G/T cg05368731 chr17:41323189 NBR1 0.66 11.31 0.52 2.01e-25 Menopause (age at onset); LIHC cis rs7703051 0.585 rs918623 chr5:74596682 A/C cg00601450 chr5:74908170 NA 0.48 6.88 0.35 2.85e-11 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.09 0.79 1.13e-75 Prudent dietary pattern; LIHC cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg02290350 chr8:58132656 NA 0.42 8.88 0.43 3.83e-17 Developmental language disorder (linguistic errors); LIHC trans rs4566357 0.595 rs2272203 chr2:227914655 C/G cg16088116 chr21:44841560 SIK1 -0.41 -6.29 -0.32 9.47e-10 Coronary artery disease; LIHC trans rs2243480 0.831 rs57294491 chr7:65684901 T/A cg10756647 chr7:56101905 PSPH -1.04 -12.49 -0.56 9.63e-30 Diabetic kidney disease; LIHC cis rs2933343 0.729 rs1680781 chr3:128612830 C/A cg25356066 chr3:128598488 ACAD9 0.56 7.77 0.39 8.97e-14 IgG glycosylation; LIHC cis rs2576037 0.526 rs1893427 chr18:44434987 C/T cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.99e-10 Personality dimensions; LIHC cis rs1348850 0.668 rs4893971 chr2:178495743 T/C cg27490568 chr2:178487706 NA 0.72 9.4 0.45 8.25e-19 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg04013166 chr16:89971882 TCF25 0.62 8.7 0.43 1.37e-16 Skin colour saturation; LIHC cis rs1403694 0.695 rs13317089 chr3:186436217 G/C cg12454167 chr3:186435060 KNG1 0.38 8.77 0.43 8.72e-17 Blood protein levels; LIHC cis rs5753618 0.561 rs1858821 chr22:31676454 T/C cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs17253792 0.822 rs113692713 chr14:56087424 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs6570726 0.599 rs426371 chr6:145886469 A/G cg05347473 chr6:146136440 FBXO30 -0.44 -6.74 -0.34 6.89e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11167764 0.895 rs7734160 chr5:141473144 G/T cg23435118 chr5:141488016 NDFIP1 -0.43 -5.77 -0.3 1.8e-8 Crohn's disease; LIHC cis rs4478037 0.642 rs77202692 chr3:33115776 A/C cg27203090 chr3:33138513 GLB1;TMPPE -0.62 -8.3 -0.41 2.37e-15 Major depressive disorder; LIHC cis rs1198430 0.925 rs1207124 chr1:23760408 A/G cg19827787 chr1:23763612 ASAP3 0.35 6.45 0.33 3.73e-10 Total cholesterol levels; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg20887711 chr4:1340912 KIAA1530 0.81 12.62 0.56 3.05e-30 Longevity; LIHC cis rs6750795 0.746 rs1667301 chr2:232423717 C/T cg19187155 chr2:232395269 NMUR1 0.55 8.41 0.41 1.12e-15 Height; LIHC cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg06634786 chr22:41940651 POLR3H 0.81 8.68 0.43 1.61e-16 Vitiligo; LIHC cis rs7131987 0.903 rs7974221 chr12:29399448 A/G cg21486233 chr12:29375141 FAR2 0.32 6.34 0.32 7.08e-10 QT interval; LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.56 0.62 1.09e-37 Prudent dietary pattern; LIHC cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg13395646 chr4:1353034 KIAA1530 -0.44 -7.03 -0.36 1.12e-11 Obesity-related traits; LIHC trans rs1814175 0.817 rs4881648 chr11:49812901 A/G cg15704280 chr7:45808275 SEPT13 -1.02 -23.53 -0.79 1.77e-73 Height; LIHC cis rs7428 0.527 rs7607284 chr2:85547376 C/G cg24342717 chr2:85555507 TGOLN2 -0.79 -10.2 -0.48 1.67e-21 Ear protrusion; LIHC cis rs60871478 1.000 rs9195 chr7:825786 C/T cg05535760 chr7:792225 HEATR2 -0.74 -10.47 -0.49 1.94e-22 Cerebrospinal P-tau181p levels; LIHC cis rs9303401 0.659 rs34351230 chr17:56782555 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs7903847 0.642 rs7074511 chr10:99140177 G/A cg20016023 chr10:99160130 RRP12 -0.42 -6.56 -0.33 2e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs919433 0.680 rs7582536 chr2:198436103 C/T cg10820045 chr2:198174542 NA -0.54 -8.63 -0.42 2.41e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 8.77 0.43 8.85e-17 Bipolar disorder; LIHC cis rs72627509 0.638 rs1608165 chr4:57894717 G/C cg26694713 chr4:57773883 REST 0.65 9.02 0.44 1.39e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs11623869 0.772 rs12587310 chr14:103907286 G/A cg26031613 chr14:104095156 KLC1 -0.74 -9.6 -0.46 1.77e-19 Bone mineral density; LIHC cis rs7131987 0.868 rs7958210 chr12:29395181 G/C cg05697976 chr12:29376483 FAR2 0.35 7.13 0.36 6.01e-12 QT interval; LIHC cis rs12079745 0.793 rs60011235 chr1:169254727 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -7.4 -0.37 1.04e-12 QT interval; LIHC cis rs2273669 0.667 rs12196143 chr6:109302372 C/T cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs10170846 0.924 rs3768973 chr2:223436402 C/T cg25565276 chr2:223520875 FARSB 0.69 10.21 0.48 1.54e-21 Schizophrenia (inflammation and infection response interaction); LIHC cis rs13223928 0.605 rs10951052 chr7:3155301 A/G cg19214707 chr7:3157722 NA -0.33 -5.89 -0.3 9.16e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs2842992 0.830 rs1475123 chr6:160178007 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.65 10.66 0.5 4.33e-23 Age-related macular degeneration (geographic atrophy); LIHC cis rs2072499 0.966 rs2984615 chr1:156165317 G/C cg25208724 chr1:156163844 SLC25A44 0.94 15.98 0.65 2.44e-43 Testicular germ cell tumor; LIHC cis rs6546550 0.901 rs3771531 chr2:70164034 T/C cg02498382 chr2:70120550 SNRNP27 -0.45 -7.64 -0.38 2.16e-13 Prevalent atrial fibrillation; LIHC cis rs908922 0.676 rs10888491 chr1:152492622 A/G cg20991723 chr1:152506922 NA 0.58 10.26 0.49 1.06e-21 Hair morphology; LIHC trans rs6934970 1.000 rs10457251 chr6:113060793 C/T cg09308777 chr6:169852575 NA 0.58 6.06 0.31 3.67e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6762 0.692 rs7928925 chr11:839155 G/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.78 -9.49 -0.46 4.23e-19 Mean platelet volume; LIHC cis rs12586317 0.547 rs4982236 chr14:35468046 C/G cg05294307 chr14:35346193 BAZ1A -0.5 -7.42 -0.37 9.26e-13 Psoriasis; LIHC trans rs1814175 0.645 rs6486022 chr11:49776137 A/G cg03929089 chr4:120376271 NA -0.83 -15.82 -0.65 1.04e-42 Height; LIHC cis rs2404602 0.679 rs12899871 chr15:76757347 T/C cg23625390 chr15:77176239 SCAPER 0.37 6.12 0.31 2.54e-9 Blood metabolite levels; LIHC cis rs7831492 0.564 rs7831530 chr8:41614567 G/A cg17182837 chr8:41585554 ANK1 -0.29 -7.2 -0.36 3.78e-12 Colorectal cancer; LIHC cis rs11792861 0.888 rs72607168 chr9:111832192 G/C cg13535736 chr9:111863775 C9orf5 -0.4 -6.0 -0.31 4.89e-9 Menarche (age at onset); LIHC cis rs1878931 0.726 rs3843728 chr16:3448251 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.99 21.86 0.76 6.53e-67 Body mass index (adult); LIHC cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg13393036 chr8:95962371 TP53INP1 -0.4 -8.98 -0.44 1.88e-17 Type 2 diabetes; LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg13152130 chr6:118910203 C6orf204 -0.65 -7.34 -0.37 1.61e-12 Diastolic blood pressure; LIHC cis rs11148252 0.574 rs7139495 chr13:53283318 A/G cg00495681 chr13:53174319 NA 0.68 12.18 0.55 1.36e-28 Lewy body disease; LIHC cis rs4803468 0.934 rs8103531 chr19:41891974 C/T cg09537434 chr19:41945824 ATP5SL -0.98 -18.97 -0.72 2.54e-55 Height; LIHC cis rs6088580 0.543 rs13042351 chr20:33238573 G/A cg08999081 chr20:33150536 PIGU -0.43 -7.42 -0.37 9.28e-13 Glomerular filtration rate (creatinine); LIHC cis rs8084351 0.577 rs10469018 chr18:50628199 T/G cg24270629 chr18:50823537 DCC 0.43 6.48 0.33 3.26e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs1670533 1.000 rs652063 chr4:1084137 T/C cg27284194 chr4:1044797 NA 0.61 8.97 0.44 1.94e-17 Recombination rate (females); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19848599 chr5:131658161 SLC22A4 -0.42 -6.3 -0.32 9.11e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.8 15.15 0.63 4.92e-40 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.15e-9 Menopause (age at onset); LIHC cis rs8141529 0.509 rs5762853 chr22:29245231 T/G cg02153584 chr22:29168773 CCDC117 0.52 7.83 0.39 6.37e-14 Lymphocyte counts; LIHC cis rs1707322 0.717 rs2275086 chr1:46085879 C/G cg06784218 chr1:46089804 CCDC17 -0.42 -7.71 -0.38 1.35e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12810548 chr4:53579237 SNORA26;KIAA0114 0.47 6.63 0.34 1.3100000000000001e-10 Lung function (FEV1/FVC); LIHC cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg02951883 chr7:2050386 MAD1L1 -0.56 -8.42 -0.41 1.04e-15 Bipolar disorder and schizophrenia; LIHC cis rs8013055 0.796 rs8005568 chr14:105971794 A/G cg19700328 chr14:106028568 NA -0.35 -7.57 -0.38 3.59e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs8180040 0.701 rs12491473 chr3:46989904 G/A cg16586182 chr3:47516702 SCAP 0.48 8.59 0.42 3.22e-16 Colorectal cancer; LIHC cis rs7208859 0.673 rs216409 chr17:28906269 C/T cg13385521 chr17:29058706 SUZ12P -0.58 -5.82 -0.3 1.38e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4853036 0.904 rs62152020 chr2:70147664 C/T cg02498382 chr2:70120550 SNRNP27 -0.4 -6.25 -0.32 1.23e-9 Colorectal or endometrial cancer; LIHC cis rs769267 0.930 rs4808967 chr19:19640524 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 5.86 0.3 1.08e-8 Tonsillectomy; LIHC cis rs425277 0.628 rs262662 chr1:2085033 A/G cg24578937 chr1:2090814 PRKCZ 0.33 6.1 0.31 2.95e-9 Height; LIHC cis rs2731664 0.819 rs449351 chr5:176872591 T/C cg23176889 chr5:176863531 GRK6 -0.73 -13.04 -0.58 7.77e-32 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg21724239 chr8:58056113 NA 0.64 7.32 0.37 1.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.913 rs10896347 chr11:68353127 G/A cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.94e-14 Total body bone mineral density; LIHC cis rs79057730 0.599 rs6944167 chr7:826274 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.75 8.55 0.42 4.13e-16 Initial pursuit acceleration; LIHC trans rs6011368 0.749 rs4809418 chr20:62915231 G/A cg13869341 chr1:15865 WASH5P -0.42 -7.14 -0.36 5.8e-12 Clozapine-induced cytotoxicity; LIHC cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg08392591 chr16:89556376 ANKRD11 0.54 8.5 0.42 6.04e-16 Multiple myeloma (IgH translocation); LIHC cis rs12701220 0.655 rs6955290 chr7:1151066 A/G cg16145915 chr7:1198662 ZFAND2A 0.35 7.12 0.36 6.4e-12 Bronchopulmonary dysplasia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09288320 chr2:210994670 C2orf67 0.28 6.35 0.32 6.79e-10 Cognitive function; LIHC cis rs3820068 0.705 rs4646072 chr1:15827711 G/A cg17385448 chr1:15911702 AGMAT 0.38 6.34 0.32 7.41e-10 Systolic blood pressure; LIHC cis rs11971779 0.680 rs4077889 chr7:139033914 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.18 0.48 1.88e-21 Diisocyanate-induced asthma; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg18905668 chr11:18388147 GTF2H1 0.35 6.39 0.33 5.5e-10 Bilirubin levels; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs918629 0.567 rs1057964 chr5:95235627 T/C cg10483112 chr5:95245456 ELL2 -0.37 -6.94 -0.35 2.03e-11 IgG glycosylation; LIHC cis rs10256972 0.521 rs7811577 chr7:1102829 C/G cg07308232 chr7:1071921 C7orf50 -0.44 -6.74 -0.34 6.69e-11 Longevity;Endometriosis; LIHC cis rs1801251 1.000 rs1022330 chr2:233577330 G/A cg08000102 chr2:233561755 GIGYF2 0.75 11.35 0.52 1.54e-25 Coronary artery disease; LIHC cis rs6752107 0.503 rs13002340 chr2:234234959 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.45 6.53 0.33 2.36e-10 Crohn's disease;Inflammatory bowel disease; LIHC trans rs637571 0.522 rs542332 chr11:65744421 C/T cg17712092 chr4:129076599 LARP1B 0.73 12.86 0.57 3.9e-31 Eosinophil percentage of white cells; LIHC cis rs896854 0.738 rs527234 chr8:95963798 C/G cg09323728 chr8:95962352 TP53INP1 0.3 5.99 0.31 5.36e-9 Type 2 diabetes; LIHC cis rs939574 1.000 rs939574 chr2:220118531 G/C cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.94 -10.18 -0.48 1.94e-21 Platelet distribution width; LIHC cis rs1816752 0.590 rs61947036 chr13:25017682 T/C cg02811702 chr13:24901961 NA 0.25 6.42 0.33 4.69e-10 Obesity-related traits; LIHC cis rs5758511 0.680 rs739146 chr22:42660414 A/G cg00645731 chr22:42541494 CYP2D7P1 0.53 8.52 0.42 5.28e-16 Birth weight; LIHC cis rs9902453 0.904 rs10853136 chr17:28406018 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.61 -0.59 5.31e-34 Coffee consumption (cups per day); LIHC cis rs6442522 0.606 rs3846128 chr3:15492150 C/T cg16303742 chr3:15540471 COLQ 0.39 6.37 0.33 6.05e-10 Uric acid levels; LIHC cis rs6963495 0.818 rs75116202 chr7:105160059 C/T cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs4072980 0.524 rs28477803 chr1:38398694 C/T cg12658694 chr1:38397304 INPP5B 0.42 6.1 0.31 2.94e-9 Coronary artery disease; LIHC cis rs6977660 0.941 rs6953957 chr7:19820560 A/G cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs7659604 0.502 rs10212738 chr4:122675724 G/A cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.7e-11 Type 2 diabetes; LIHC cis rs1008375 0.932 rs964012 chr4:17619184 A/G cg02297831 chr4:17616191 MED28 0.45 6.34 0.32 7.39e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2439831 1.000 rs690263 chr15:43704465 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.8 13.33 0.58 6.13e-33 Lung cancer in ever smokers; LIHC cis rs317689 0.513 rs529268 chr12:69687051 G/A cg20891283 chr12:69753455 YEATS4 0.65 10.84 0.51 1.01e-23 Response to diuretic therapy; LIHC cis rs988712 0.622 rs2030323 chr11:27728539 A/C cg18117895 chr11:27722066 BDNF -0.49 -6.85 -0.35 3.39e-11 Obesity; LIHC cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg18252515 chr7:66147081 NA 1.29 16.87 0.67 7.21e-47 Diabetic kidney disease; LIHC cis rs4665809 1.000 rs7573118 chr2:26308086 A/G cg27170947 chr2:26402098 FAM59B -0.62 -7.72 -0.39 1.27e-13 Gut microbiome composition (summer); LIHC cis rs4803468 1.000 rs2241706 chr19:41912807 A/G cg09537434 chr19:41945824 ATP5SL -1.01 -21.33 -0.76 8.44e-65 Height; LIHC cis rs6762477 0.748 rs2073726 chr3:50223593 T/A cg24110177 chr3:50126178 RBM5 0.38 5.83 0.3 1.28e-8 Menarche (age at onset); LIHC cis rs61542988 0.570 rs10950919 chr7:22833821 A/G cg11367502 chr7:22862612 TOMM7 0.57 9.29 0.45 1.84e-18 Fibrinogen levels; LIHC cis rs116095464 0.558 rs10076655 chr5:239464 G/C cg22496380 chr5:211416 CCDC127 -1.03 -10.71 -0.5 2.89e-23 Breast cancer; LIHC cis rs10504073 0.669 rs12548464 chr8:50023867 C/T cg00325661 chr8:49890786 NA 0.3 6.82 0.35 4.05e-11 Blood metabolite ratios; LIHC cis rs611744 0.967 rs651814 chr8:109196571 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg16405210 chr4:1374714 KIAA1530 0.86 14.76 0.62 1.65e-38 Longevity; LIHC cis rs924607 0.898 rs1697990 chr5:626278 A/G cg04221910 chr5:616842 CEP72 -0.4 -7.53 -0.38 4.48e-13 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7520050 0.931 rs1707333 chr1:46547035 C/G cg03146154 chr1:46216737 IPP -0.38 -6.2 -0.32 1.59e-9 Red blood cell count;Reticulocyte count; LIHC cis rs703842 0.963 rs2291617 chr12:58166403 T/G cg18357645 chr12:58087776 OS9 -0.44 -6.77 -0.34 5.59e-11 Multiple sclerosis; LIHC cis rs6060717 0.610 rs2244883 chr20:34620896 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -7.91 -0.39 3.49e-14 Hip circumference adjusted for BMI; LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg11494091 chr17:61959527 GH2 0.45 8.32 0.41 2.12e-15 Prudent dietary pattern; LIHC cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.9 -0.35 2.6e-11 Gut microbiome composition (summer); LIHC cis rs7264396 0.790 rs6121015 chr20:34243017 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -9.48 -0.46 4.42e-19 Total cholesterol levels; LIHC cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.04 -0.48 5.96e-21 Platelet count; LIHC cis rs2050392 0.624 rs303449 chr10:30726845 G/A cg02070205 chr10:30722105 MAP3K8 -0.44 -5.93 -0.31 7.37e-9 Inflammatory bowel disease; LIHC cis rs1801251 1.000 rs2675971 chr2:233726154 A/G cg25237894 chr2:233734115 C2orf82 -0.58 -11.33 -0.52 1.73e-25 Coronary artery disease; LIHC cis rs10254118 0.757 rs6467491 chr7:133138761 A/G cg10665199 chr7:133106180 EXOC4 0.53 8.61 0.42 2.65e-16 Intelligence (multi-trait analysis); LIHC cis rs227584 0.663 rs3180912 chr17:42259463 A/G cg08499158 chr17:42289980 UBTF -0.41 -6.63 -0.34 1.32e-10 Bone mineral density (hip);Bone mineral density; LIHC cis rs17826219 0.706 rs9905827 chr17:29192168 C/A cg14067834 chr17:29058358 SUZ12P 0.66 6.45 0.33 3.92e-10 Body mass index; LIHC cis rs611744 0.967 rs673015 chr8:109191669 C/T cg21045802 chr8:109455806 TTC35 0.54 9.35 0.45 1.15e-18 Dupuytren's disease; LIHC cis rs1997103 1.000 rs12532070 chr7:55407698 A/G cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs8180040 0.701 rs7617689 chr3:46996442 C/T cg27129171 chr3:47204927 SETD2 -0.6 -10.23 -0.48 1.3e-21 Colorectal cancer; LIHC cis rs9303401 0.614 rs28651036 chr17:57080471 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.81 0.54 3.03e-27 Cognitive test performance; LIHC cis rs477692 0.685 rs534430 chr10:131398734 A/C cg05714579 chr10:131428358 MGMT 0.45 7.64 0.38 2.23e-13 Response to temozolomide; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16472210 chr3:81810621 GBE1 -0.43 -6.44 -0.33 3.95e-10 Pancreatic cancer; LIHC cis rs56235845 0.694 rs36102285 chr5:176774018 C/T cg16006841 chr5:176797999 RGS14 0.58 7.92 0.39 3.33e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs2997447 0.846 rs3008420 chr1:26401403 C/T cg19633962 chr1:26362018 EXTL1 -0.53 -6.0 -0.31 5.11e-9 QRS complex (12-leadsum); LIHC cis rs7617773 0.747 rs34076262 chr3:48370416 C/T cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg05590025 chr7:65112418 INTS4L2 0.62 6.79 0.34 4.9e-11 Diabetic kidney disease; LIHC cis rs2070488 0.775 rs11926767 chr3:38527913 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.64 -10.1 -0.48 3.73e-21 Electrocardiographic conduction measures; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16458507 chr12:113376293 OAS3 -0.46 -7.07 -0.36 9.02e-12 Pancreatic cancer; LIHC cis rs7116495 0.737 rs693648 chr11:71570446 G/A cg26138937 chr11:71823887 C11orf51 0.69 6.62 0.34 1.4e-10 Severe influenza A (H1N1) infection; LIHC cis rs1577917 1.000 rs10455455 chr6:86670214 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.1 -0.48 3.72e-21 Response to antipsychotic treatment; LIHC cis rs6121246 0.697 rs6088856 chr20:30226543 C/G cg13852791 chr20:30311386 BCL2L1 0.8 7.99 0.4 2.1e-14 Mean corpuscular hemoglobin; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.83 -0.3 1.25e-8 Total body bone mineral density; LIHC cis rs6754311 0.512 rs12998387 chr2:136507039 A/G cg07169764 chr2:136633963 MCM6 -0.68 -9.78 -0.47 4.41e-20 Mosquito bite size; LIHC cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.67 6.33 0.32 7.88e-10 Lung function (FEV1/FVC); LIHC trans rs10411161 1.000 rs8108477 chr19:52364902 C/T cg22319618 chr22:45562946 NUP50 -0.53 -7.16 -0.36 4.92e-12 Breast cancer; LIHC cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg08859206 chr1:53392774 SCP2 -0.38 -6.24 -0.32 1.31e-9 Monocyte count; LIHC cis rs10461617 0.617 rs1423623 chr5:56065575 A/G cg22800045 chr5:56110881 MAP3K1 -0.55 -7.47 -0.37 6.88e-13 Type 2 diabetes; LIHC cis rs7615952 0.688 rs12638240 chr3:125541238 G/A cg05084668 chr3:125655381 ALG1L -0.35 -6.33 -0.32 7.7e-10 Blood pressure (smoking interaction); LIHC cis rs7662987 0.517 rs1311618 chr4:100012612 A/G cg12011299 chr4:100065546 ADH4 0.65 10.73 0.5 2.43e-23 Smoking initiation; LIHC cis rs8062405 1.000 rs7205323 chr16:28865892 C/T cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2952156 0.920 rs12150298 chr17:37834541 T/C cg00129232 chr17:37814104 STARD3 -0.53 -10.21 -0.48 1.57e-21 Asthma; LIHC cis rs208515 0.525 rs9453538 chr6:66668508 G/A cg07460842 chr6:66804631 NA 0.79 8.92 0.43 2.84e-17 Exhaled nitric oxide levels; LIHC cis rs919433 0.617 rs10931791 chr2:198573612 A/C cg03934865 chr2:198174659 NA -0.45 -6.44 -0.33 4.06e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10503871 0.545 rs13253760 chr8:30503792 C/T cg26383811 chr8:30366931 RBPMS -0.4 -6.37 -0.33 6.13e-10 Metabolite levels (X-11787); LIHC cis rs2839627 0.561 rs1107830 chr21:44275097 G/A cg18192155 chr21:44258298 NA 0.45 7.12 0.36 6.5e-12 Information processing speed; LIHC cis rs400736 0.930 rs226249 chr1:8021778 A/G cg25007680 chr1:8021821 PARK7 0.63 9.87 0.47 2.26e-20 Response to antidepressants and depression; LIHC cis rs507080 0.883 rs656575 chr11:118549908 T/G cg04173919 chr11:118528438 PHLDB1 0.31 5.85 0.3 1.12e-8 Serum metabolite levels; LIHC cis rs73001065 0.711 rs58489806 chr19:19456917 C/T cg03709012 chr19:19516395 GATAD2A 0.76 7.52 0.38 4.87e-13 LDL cholesterol; LIHC cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg17372223 chr3:52568218 NT5DC2 0.36 5.95 0.31 6.57e-9 Electroencephalogram traits; LIHC cis rs9522267 0.535 rs7323631 chr13:112232269 A/G cg10483660 chr13:112241077 NA -0.22 -5.88 -0.3 9.86e-9 Hepatitis; LIHC cis rs947211 0.898 rs1775146 chr1:205756168 A/G cg14893161 chr1:205819251 PM20D1 0.35 6.03 0.31 4.19e-9 Parkinson's disease; LIHC cis rs2635047 0.638 rs2668784 chr18:44711391 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.93 0.31 7.28e-9 Educational attainment; LIHC cis rs970821 0.900 rs10097319 chr8:124755313 C/T cg00283535 chr8:124749564 ANXA13 0.37 6.04 0.31 4.02e-9 Breast cancer; LIHC cis rs5769707 0.642 rs135880 chr22:50018654 T/A cg01652190 chr22:50026171 C22orf34 -0.34 -7.64 -0.38 2.2e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6570726 0.935 rs585292 chr6:145862228 T/C cg23711669 chr6:146136114 FBXO30 0.56 10.02 0.48 7.09e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs910316 0.763 rs175057 chr14:75489632 C/T cg11812906 chr14:75593930 NEK9 -0.65 -11.43 -0.53 7.72e-26 Height; LIHC cis rs4268898 0.722 rs11680491 chr2:24416292 T/A cg06627628 chr2:24431161 ITSN2 0.49 7.06 0.36 9.53e-12 Asthma; LIHC cis rs263063 0.764 rs12979556 chr19:5076856 G/A cg18473234 chr19:5097819 KDM4B 0.56 6.99 0.35 1.47e-11 Periodontitis (CDC/AAP); LIHC cis rs9457247 0.663 rs6456143 chr6:167415440 C/A cg23791538 chr6:167370224 RNASET2 -0.6 -10.34 -0.49 5.34e-22 Crohn's disease; LIHC cis rs4148883 0.504 rs4585310 chr4:100120233 T/C cg12011299 chr4:100065546 ADH4 -0.32 -6.51 -0.33 2.71e-10 Alcohol dependence; LIHC cis rs10078 0.510 rs2278248 chr5:469570 G/T cg26072250 chr5:443457 EXOC3;C5orf55 0.61 8.47 0.42 7.51e-16 Fat distribution (HIV); LIHC cis rs7131987 0.903 rs6487796 chr12:29422764 A/G cg12903224 chr12:29470962 FAR2 -0.42 -6.81 -0.35 4.43e-11 QT interval; LIHC cis rs769267 0.930 rs10402451 chr19:19608537 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.87 0.3 1.05e-8 Tonsillectomy; LIHC cis rs1538970 1.000 rs1417578 chr1:45850590 A/G cg24296786 chr1:45957014 TESK2 -0.5 -7.61 -0.38 2.62e-13 Platelet count; LIHC cis rs6545883 0.929 rs10200055 chr2:61628017 T/A cg15711740 chr2:61764176 XPO1 0.43 6.0 0.31 5e-9 Tuberculosis; LIHC cis rs6951245 0.542 rs28460147 chr7:1217192 G/A cg03188948 chr7:1209495 NA 0.86 6.07 0.31 3.34e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1580019 0.522 rs10951340 chr7:32562408 G/A cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.2 0.32 1.66e-9 Cognitive ability; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg21782813 chr7:2030301 MAD1L1 0.56 10.28 0.49 8.94e-22 Bipolar disorder and schizophrenia; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg03721293 chr16:90014378 DEF8 0.43 7.27 0.37 2.53e-12 Skin colour saturation; LIHC trans rs1005277 0.579 rs1780136 chr10:38501453 A/G cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs10256972 0.647 rs10233430 chr7:1051664 T/C cg07308232 chr7:1071921 C7orf50 -0.39 -6.1 -0.31 2.82e-9 Longevity;Endometriosis; LIHC cis rs10927875 0.832 rs4661342 chr1:16160773 C/G cg07117364 chr1:16154769 NA -0.4 -5.88 -0.3 9.97e-9 Dilated cardiomyopathy; LIHC cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg26818010 chr10:134567672 INPP5A -0.73 -9.53 -0.46 2.98e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs644799 0.932 rs10831447 chr11:95663017 C/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.52 -6.77 -0.34 5.63e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs853679 0.517 rs2273564 chr6:28057594 A/T cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs9733 0.526 rs6587542 chr1:150907701 G/T cg17724175 chr1:150552817 MCL1 0.38 7.59 0.38 3.03e-13 Tonsillectomy; LIHC cis rs10479542 0.892 rs7723230 chr5:178980474 T/C cg19723775 chr5:179050963 HNRNPH1 0.38 5.93 0.31 7.25e-9 Lung cancer; LIHC cis rs1862618 0.671 rs2591955 chr5:56244948 C/T cg24531977 chr5:56204891 C5orf35 0.52 7.47 0.37 6.66e-13 Initial pursuit acceleration; LIHC cis rs7927592 0.956 rs2510384 chr11:68391837 C/A cg01657329 chr11:68192670 LRP5 -0.46 -5.99 -0.31 5.18e-9 Total body bone mineral density; LIHC cis rs616402 0.527 rs604369 chr1:10567208 C/A cg17425144 chr1:10567563 PEX14 0.63 13.1 0.58 4.69e-32 Breast size; LIHC cis rs11711311 0.712 rs11718013 chr3:113341661 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.37 -6.51 -0.33 2.66e-10 IgG glycosylation; LIHC cis rs4689592 0.554 rs66925245 chr4:7071999 C/T cg26116260 chr4:7069785 GRPEL1 -1.04 -17.59 -0.69 8.92e-50 Monocyte percentage of white cells; LIHC cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.62 0.34 1.4e-10 Bipolar disorder; LIHC cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg05025164 chr4:1340916 KIAA1530 -0.72 -11.25 -0.52 3.46e-25 Longevity; LIHC cis rs875971 1.000 rs2042133 chr7:65931922 A/G cg18876405 chr7:65276391 NA 0.38 6.86 0.35 3.22e-11 Aortic root size; LIHC cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg17971929 chr21:40555470 PSMG1 -0.48 -7.26 -0.37 2.66e-12 Cognitive function; LIHC trans rs7980799 0.682 rs10437795 chr12:33635336 C/G cg26384229 chr12:38710491 ALG10B -0.45 -6.07 -0.31 3.34e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs7618501 0.602 rs2071206 chr3:50160109 G/A cg24110177 chr3:50126178 RBM5 0.51 8.27 0.41 3e-15 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.951 rs12777021 chr10:967270 T/C cg20503657 chr10:835505 NA 1.07 11.23 0.52 4.09e-25 Eosinophil percentage of granulocytes; LIHC cis rs10751667 0.560 rs10902267 chr11:1007831 T/C ch.11.42038R chr11:967971 AP2A2 0.58 10.59 0.5 7.32e-23 Alzheimer's disease (late onset); LIHC cis rs2576037 0.526 rs605487 chr18:44444778 G/C cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.99e-10 Personality dimensions; LIHC cis rs597539 0.652 rs636049 chr11:68667198 A/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 11.38 0.52 1.15e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6988636 1.000 rs13261021 chr8:124190239 G/A cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs6963495 0.818 rs73190181 chr7:105162907 A/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs801193 0.935 rs3800820 chr7:66147178 C/T cg18876405 chr7:65276391 NA -0.43 -7.56 -0.38 3.72e-13 Aortic root size; LIHC cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg24879335 chr3:133465180 TF 0.28 6.36 0.33 6.58e-10 Iron status biomarkers; LIHC cis rs5753618 0.561 rs2073857 chr22:31658281 A/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs3008870 1.000 rs2755245 chr1:67487964 C/G cg02640540 chr1:67518911 SLC35D1 0.45 6.12 0.31 2.51e-9 Lymphocyte percentage of white cells; LIHC cis rs1075232 1.000 rs34959140 chr15:31725223 G/A cg01030201 chr15:31746330 NA -0.86 -6.64 -0.34 1.22e-10 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs748404 0.660 rs690472 chr15:43764368 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.3 0.37 2.01e-12 Lung cancer; LIHC cis rs2637266 0.967 rs10400134 chr10:78365158 G/C cg18941641 chr10:78392320 NA 0.31 6.68 0.34 9.91e-11 Pulmonary function; LIHC cis rs6733011 0.644 rs6719634 chr2:99460614 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.44 -6.09 -0.31 2.96e-9 Bipolar disorder; LIHC cis rs6502050 0.799 rs7406257 chr17:80089340 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC cis rs7208859 0.673 rs61348930 chr17:29221763 C/T cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9399135 0.967 rs2183709 chr6:135377091 C/T cg22676075 chr6:135203613 NA 0.42 6.67 0.34 1.02e-10 Red blood cell count; LIHC cis rs3806843 0.966 rs2563264 chr5:140137503 T/G cg19875535 chr5:140030758 IK -0.37 -5.97 -0.31 5.81e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs896854 0.967 rs896853 chr8:95960855 G/C cg16049864 chr8:95962084 TP53INP1 -0.67 -13.1 -0.58 4.87e-32 Type 2 diabetes; LIHC cis rs1371867 0.817 rs1788179 chr8:101333345 A/G cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC cis rs6088590 0.965 rs6120727 chr20:33374102 T/C cg06115741 chr20:33292138 TP53INP2 0.59 8.05 0.4 1.41e-14 Coronary artery disease; LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.59 0.56 4.01e-30 Prudent dietary pattern; LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg18306943 chr3:40428807 ENTPD3 0.39 6.71 0.34 8.13e-11 Renal cell carcinoma; LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg07021052 chr2:20871279 NA -0.39 -7.0 -0.35 1.39e-11 Abdominal aortic aneurysm; LIHC cis rs36051895 0.623 rs2381215 chr9:5262607 C/T cg02405213 chr9:5042618 JAK2 -0.64 -9.93 -0.47 1.38e-20 Pediatric autoimmune diseases; LIHC cis rs11971779 0.680 rs1986447 chr7:139082080 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs10420951 0.573 rs76184771 chr19:18567189 A/G cg10790698 chr19:18539756 SSBP4 -0.43 -6.05 -0.31 3.87e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17817474 chr15:90809403 NGRN 0.43 6.75 0.34 6.39e-11 Cognitive function; LIHC cis rs9399135 0.967 rs6909975 chr6:135315570 C/T cg22676075 chr6:135203613 NA 0.37 6.14 0.32 2.3e-9 Red blood cell count; LIHC cis rs3008870 0.959 rs2985810 chr1:67376162 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.48 0.67 2.53e-45 Lymphocyte percentage of white cells; LIHC cis rs7615952 0.599 rs16834938 chr3:125706046 C/T cg05084668 chr3:125655381 ALG1L -0.42 -6.75 -0.34 6.26e-11 Blood pressure (smoking interaction); LIHC cis rs4555082 0.834 rs2816651 chr14:105708470 A/G cg10792982 chr14:105748885 BRF1 0.44 6.02 0.31 4.57e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs6430585 0.759 rs4954623 chr2:136535876 G/A cg07169764 chr2:136633963 MCM6 -1.08 -15.22 -0.64 2.63e-40 Corneal structure; LIHC cis rs11098499 0.866 rs12374244 chr4:120281972 A/T cg09307838 chr4:120376055 NA 0.63 9.65 0.46 1.17e-19 Corneal astigmatism; LIHC cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg06238570 chr21:40685208 BRWD1 -0.38 -6.16 -0.32 2.03e-9 Menarche (age at onset); LIHC cis rs933688 1.000 rs1035477 chr5:90743325 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.2 0.66 3.29e-44 Smoking behavior; LIHC trans rs116095464 0.558 rs9654452 chr5:299561 C/T cg00938859 chr5:1591904 SDHAP3 0.52 6.26 0.32 1.15e-9 Breast cancer; LIHC cis rs7075426 0.524 rs12779025 chr10:88188716 T/A cg07322936 chr10:88137208 NA 0.49 6.01 0.31 4.71e-9 Migraine without aura; LIHC cis rs116095464 0.614 rs56299325 chr5:220594 C/T cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs950169 0.922 rs12911223 chr15:84831671 G/A cg17507749 chr15:85114479 UBE2QP1 -0.73 -8.81 -0.43 6.38e-17 Schizophrenia; LIHC cis rs1008375 1.000 rs1008374 chr4:17683219 G/A cg02297831 chr4:17616191 MED28 0.42 6.7 0.34 8.36e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg23024448 chr19:51222118 NA -0.59 -6.04 -0.31 4.1e-9 Mean platelet volume; LIHC trans rs57221529 0.766 rs72706610 chr5:561111 G/A cg25482853 chr8:67687455 SGK3 0.67 6.66 0.34 1.09e-10 Lung disease severity in cystic fibrosis; LIHC cis rs1577917 1.000 rs12665321 chr6:86769289 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.04 -0.48 5.98e-21 Response to antipsychotic treatment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10578084 chr7:1288010 NA 0.43 6.51 0.33 2.63e-10 Lung function (FEV1/FVC); LIHC cis rs919433 0.679 rs55656916 chr2:198519628 T/C cg03934865 chr2:198174659 NA 0.47 6.99 0.35 1.42e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17401966 0.931 rs12408430 chr1:10323339 T/A cg19773385 chr1:10388646 KIF1B -0.41 -7.33 -0.37 1.67e-12 Hepatocellular carcinoma; LIHC cis rs1538970 0.781 rs11211139 chr1:46015751 G/T cg24296786 chr1:45957014 TESK2 -0.49 -6.38 -0.33 5.64e-10 Platelet count; LIHC cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg24250549 chr1:154909240 PMVK 0.69 11.05 0.51 1.78e-24 Prostate cancer; LIHC cis rs734999 0.588 rs4648562 chr1:2535613 C/A cg18854424 chr1:2615690 NA 0.32 6.96 0.35 1.77e-11 Ulcerative colitis; LIHC cis rs6598955 0.640 rs6667826 chr1:26531408 T/C cg04990556 chr1:26633338 UBXN11 -0.56 -8.97 -0.44 2.06e-17 Obesity-related traits; LIHC cis rs7561273 0.586 rs11896092 chr2:24317827 G/A cg06627628 chr2:24431161 ITSN2 -0.44 -5.89 -0.3 9.14e-9 Quantitative traits; LIHC cis rs965469 1.000 rs6051745 chr20:3307243 T/G cg25506879 chr20:3388711 C20orf194 -0.57 -6.83 -0.35 3.86e-11 IFN-related cytopenia; LIHC cis rs10463316 0.862 rs11740475 chr5:150777997 A/G cg03212797 chr5:150827313 SLC36A1 -0.44 -6.68 -0.34 9.54e-11 Metabolite levels (Pyroglutamine); LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg11494091 chr17:61959527 GH2 0.36 6.06 0.31 3.62e-9 Height; LIHC cis rs611744 0.901 rs639746 chr8:109234825 T/C cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs12477438 0.765 rs2167930 chr2:99592551 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.02 -0.51 2.28e-24 Chronic sinus infection; LIHC cis rs60733400 0.782 rs4648564 chr1:2562169 C/T cg18854424 chr1:2615690 NA -0.34 -7.38 -0.37 1.22e-12 Multiple sclerosis; LIHC cis rs1728785 1.000 rs1645976 chr16:68563509 T/C cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.49 -0.42 6.28e-16 Lymphocyte counts; LIHC cis rs77741769 0.507 rs11065264 chr12:121218380 T/G cg02419362 chr12:121203948 SPPL3 0.34 5.76 0.3 1.91e-8 Mean corpuscular volume; LIHC cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg23149560 chr2:74406255 MOBKL1B 0.41 5.83 0.3 1.29e-8 Gestational age at birth (maternal effect); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17187048 chr2:122407283 CLASP1 0.51 7.14 0.36 5.58e-12 Pancreatic cancer; LIHC trans rs9929218 1.000 rs28450087 chr16:68803726 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.78 -0.43 8.25e-17 Colorectal cancer; LIHC cis rs12744310 1.000 rs12041533 chr1:41768271 C/T cg03962019 chr1:41807865 NA 0.4 6.44 0.33 4.14e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2204008 0.806 rs3922574 chr12:38329069 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.41e-15 Bladder cancer; LIHC cis rs796364 0.806 rs188102 chr2:200903189 T/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -7.23 -0.36 3.27e-12 Schizophrenia; LIHC cis rs9818758 0.607 rs34823813 chr3:49749976 G/A cg07636037 chr3:49044803 WDR6 -0.69 -5.79 -0.3 1.56e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1552244 0.554 rs3732963 chr3:10048885 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC trans rs7193541 0.684 rs7201320 chr16:74694058 T/G cg23598604 chr1:99732472 LPPR4 -0.3 -6.39 -0.33 5.5e-10 Multiple myeloma; LIHC cis rs801193 0.805 rs12532355 chr7:66070584 C/G cg11764359 chr7:65958608 NA -0.62 -9.43 -0.45 6.42e-19 Aortic root size; LIHC cis rs798554 0.797 rs798494 chr7:2798294 C/A cg19346786 chr7:2764209 NA -0.46 -7.03 -0.36 1.15e-11 Height; LIHC cis rs7224737 1.000 rs2240009 chr17:40283142 C/G cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg09367891 chr1:107599246 PRMT6 -0.68 -10.85 -0.51 9.32e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3789045 0.685 rs12036042 chr1:204469314 T/C cg17419461 chr1:204415978 PIK3C2B -0.4 -6.05 -0.31 3.86e-9 Educational attainment (college completion); LIHC cis rs1008375 1.000 rs28497813 chr4:17685503 A/G cg02297831 chr4:17616191 MED28 0.43 6.8 0.35 4.6e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs1814175 0.586 rs2866862 chr11:49954588 T/C cg15704280 chr7:45808275 SEPT13 -0.96 -19.81 -0.73 1.07e-58 Height; LIHC cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg05564831 chr3:52568323 NT5DC2 0.36 5.84 0.3 1.21e-8 Bipolar disorder; LIHC cis rs882732 1.000 rs10133253 chr14:95033681 A/G cg14866387 chr14:95027382 SERPINA4 -0.45 -6.73 -0.34 7.03e-11 Blood protein levels; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.46 -6.97 -0.35 1.64e-11 Total body bone mineral density; LIHC cis rs7923837 0.650 rs10882098 chr10:94444793 C/T cg25506282 chr10:94462361 NA 0.41 7.22 0.36 3.44e-12 Body mass index;Multiple sclerosis; LIHC cis rs7520050 0.808 rs11211195 chr1:46282295 T/C cg03146154 chr1:46216737 IPP -0.39 -6.51 -0.33 2.69e-10 Red blood cell count;Reticulocyte count; LIHC cis rs875971 0.660 rs801193 chr7:66030612 A/C cg11764359 chr7:65958608 NA -0.68 -10.36 -0.49 4.7e-22 Aortic root size; LIHC cis rs6748734 1.000 rs4675863 chr2:241830763 A/T cg08694578 chr2:241835147 C2orf54 -0.51 -7.16 -0.36 4.88e-12 Urinary metabolites; LIHC cis rs6546550 0.933 rs57278310 chr2:70093647 T/C cg02498382 chr2:70120550 SNRNP27 -0.38 -6.35 -0.32 6.83e-10 Prevalent atrial fibrillation; LIHC cis rs3796352 0.527 rs11716506 chr3:52944328 C/T cg04865290 chr3:52927548 TMEM110 -0.49 -6.44 -0.33 4.07e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs60871478 0.588 rs73043546 chr7:857513 C/G cg05535760 chr7:792225 HEATR2 -0.78 -6.04 -0.31 3.92e-9 Cerebrospinal P-tau181p levels; LIHC cis rs9916302 0.904 rs2338800 chr17:37498149 C/G cg07936489 chr17:37558343 FBXL20 0.83 13.33 0.58 6.38e-33 Glomerular filtration rate (creatinine); LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.76 -0.34 6.07e-11 Total body bone mineral density; LIHC trans rs3960554 0.660 rs55671363 chr7:75793405 T/C cg19862616 chr7:65841803 NCRNA00174 0.89 15.82 0.65 1.09e-42 Eotaxin levels; LIHC cis rs6701037 0.681 rs6664840 chr1:175128726 A/G cg00958927 chr1:175162553 KIAA0040 -0.39 -6.46 -0.33 3.61e-10 Alcohol dependence; LIHC cis rs7959452 0.535 rs1350166 chr12:69636314 G/T cg14784868 chr12:69753453 YEATS4 0.86 16.11 0.66 7.9e-44 Blood protein levels; LIHC cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.55e-21 Intelligence (multi-trait analysis); LIHC cis rs7617773 0.780 rs35190747 chr3:48343290 C/T cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg25329296 chr4:113486062 C4orf21 0.41 6.19 0.32 1.68e-9 Alopecia areata; LIHC trans rs7618501 1.000 rs4855867 chr3:49745822 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.49 0.42 6.51e-16 Platelet count; LIHC cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs7512552 0.839 rs698919 chr1:150387000 A/G cg15654264 chr1:150340011 RPRD2 0.68 11.1 0.51 1.2e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs801193 1.000 rs3778909 chr7:66255646 G/C cg18876405 chr7:65276391 NA 0.43 7.4 0.37 1.06e-12 Aortic root size; LIHC cis rs11190604 1.000 rs11190551 chr10:102204734 A/G cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1801251 1.000 rs4973054 chr2:233710713 G/C cg08000102 chr2:233561755 GIGYF2 -0.76 -11.53 -0.53 3.33e-26 Coronary artery disease; LIHC cis rs7552404 0.960 rs12134854 chr1:76137606 A/G cg22875332 chr1:76189707 ACADM 0.46 6.95 0.35 1.91e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg04025307 chr7:1156635 C7orf50 0.57 9.23 0.45 2.81e-18 Longevity;Endometriosis; LIHC cis rs9296092 0.517 rs11751684 chr6:33528739 G/T cg13560919 chr6:33536144 NA -0.4 -6.57 -0.33 1.92e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs1538970 0.816 rs12029322 chr1:45970446 C/T cg05343316 chr1:45956843 TESK2 0.63 9.49 0.46 4.11e-19 Platelet count; LIHC cis rs870825 0.616 rs72705689 chr4:185639894 A/G cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs7089973 0.604 rs11196939 chr10:116593175 A/G cg23260525 chr10:116636907 FAM160B1 -0.35 -6.65 -0.34 1.13e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs919433 0.662 rs2043018 chr2:198236958 G/A cg10820045 chr2:198174542 NA 0.56 8.88 0.43 3.78e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg03188948 chr7:1209495 NA 0.45 6.38 0.33 5.88e-10 Longevity;Endometriosis; LIHC cis rs12744310 1.000 rs34073585 chr1:41777199 T/C cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs17106184 1.000 rs72904718 chr1:51315456 T/C cg07174182 chr1:51127561 FAF1 -0.62 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC trans rs72960926 0.744 rs55764691 chr6:74924388 T/C cg07247405 chr1:2484626 LOC115110 0.56 6.62 0.34 1.36e-10 Metabolite levels (MHPG); LIHC cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg07424592 chr7:64974309 NA 0.82 9.43 0.45 6.33e-19 Diabetic kidney disease; LIHC cis rs6701037 0.566 rs10489326 chr1:175134677 A/G cg17845761 chr1:175162550 KIAA0040 0.41 6.96 0.35 1.76e-11 Alcohol dependence; LIHC trans rs2739330 0.828 rs2154593 chr22:24252085 A/G cg06437703 chr8:37914619 EIF4EBP1 -0.48 -7.27 -0.37 2.54e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1506636 1.000 rs676755 chr7:123439082 A/G cg03229431 chr7:123269106 ASB15 -0.5 -9.19 -0.45 3.85e-18 Plateletcrit;Platelet count; LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg02018176 chr4:1364513 KIAA1530 0.43 5.85 0.3 1.18e-8 Longevity; LIHC cis rs12477438 0.539 rs62156558 chr2:99553104 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -8.43 -0.41 9.8e-16 Chronic sinus infection; LIHC cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.4 6.88 0.35 2.95e-11 Electroencephalogram traits; LIHC cis rs2075371 0.932 rs2241332 chr7:133969439 A/G cg11752832 chr7:134001865 SLC35B4 0.47 5.9 0.3 8.82e-9 Mean platelet volume; LIHC cis rs1707322 0.927 rs6690386 chr1:46253011 C/T cg03146154 chr1:46216737 IPP 0.5 7.8 0.39 7.36e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 1.000 rs9829800 chr3:40443927 T/C cg13409248 chr3:40428643 ENTPD3 0.39 6.36 0.33 6.45e-10 Renal cell carcinoma; LIHC cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg16405210 chr4:1374714 KIAA1530 -0.63 -10.25 -0.48 1.16e-21 Obesity-related traits; LIHC cis rs6952808 0.965 rs11768541 chr7:1894884 G/A cg14004847 chr7:1930337 MAD1L1 -0.44 -6.06 -0.31 3.57e-9 Bipolar disorder and schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21890592 chr7:5013639 RNF216L -0.54 -6.47 -0.33 3.43e-10 Systolic blood pressure; LIHC cis rs9517320 0.517 rs4772097 chr13:99194652 C/A cg20487152 chr13:99095054 FARP1 -0.38 -6.16 -0.32 2.01e-9 Longevity; LIHC cis rs6831352 0.918 rs13140423 chr4:100050400 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs11030122 0.702 rs10835312 chr11:3950253 G/A cg18678763 chr11:4115507 RRM1 -0.58 -8.59 -0.42 3.21e-16 Mean platelet volume;Platelet distribution width; LIHC trans rs4820294 0.770 rs7285699 chr22:38066556 A/C cg19894588 chr14:64061835 NA -0.45 -7.12 -0.36 6.3e-12 Fat distribution (HIV); LIHC cis rs11871801 1.000 rs78594996 chr17:40570109 A/G cg14558262 chr17:40713999 COASY 0.46 5.74 0.3 2.04e-8 Crohn's disease; LIHC cis rs787274 1.000 rs7859381 chr9:115546649 C/T cg13803584 chr9:115635662 SNX30 -0.59 -6.33 -0.32 7.74e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs4824093 0.610 rs7410534 chr22:50289925 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -5.83 -0.3 1.29e-8 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs12478296 1.000 rs66612947 chr2:243035962 A/T cg06360820 chr2:242988706 NA -0.85 -11.96 -0.54 9.18e-28 Obesity-related traits; LIHC cis rs11030122 0.702 rs11030276 chr11:3946134 A/G cg18678763 chr11:4115507 RRM1 -0.58 -8.59 -0.42 3.21e-16 Mean platelet volume;Platelet distribution width; LIHC trans rs2579103 0.767 rs1347845 chr12:90663011 A/G cg00091569 chr3:40428383 ENTPD3 0.39 6.17 0.32 1.89e-9 Body mass index; LIHC cis rs3213545 0.659 rs2259693 chr12:121457995 G/A cg25281562 chr12:121454272 C12orf43 0.38 6.44 0.33 4.1e-10 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs6546550 0.901 rs10496174 chr2:70153436 T/G cg02498382 chr2:70120550 SNRNP27 -0.45 -7.74 -0.39 1.1e-13 Prevalent atrial fibrillation; LIHC cis rs2228479 0.850 rs17226498 chr16:89840631 T/C cg00800038 chr16:89945340 TCF25 -0.63 -9.48 -0.46 4.32e-19 Skin colour saturation; LIHC cis rs7613875 0.620 rs13079006 chr3:49996924 G/T cg05623727 chr3:50126028 RBM5 0.33 5.82 0.3 1.35e-8 Body mass index; LIHC cis rs765787 0.530 rs2668737 chr15:45522799 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.5 -0.38 5.73e-13 Uric acid levels; LIHC cis rs597539 0.652 rs674654 chr11:68698762 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.74 10.16 0.48 2.21e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs425277 1.000 rs262641 chr1:2104981 C/T cg24578937 chr1:2090814 PRKCZ -0.5 -8.96 -0.44 2.17e-17 Height; LIHC trans rs11098499 0.754 rs10213267 chr4:120239074 A/G cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs10751667 0.600 rs10751665 chr11:941300 G/A ch.11.42038R chr11:967971 AP2A2 0.53 9.72 0.47 7.06e-20 Alzheimer's disease (late onset); LIHC cis rs10197940 0.571 rs13393021 chr2:152413258 A/C cg06191203 chr2:152266755 RIF1 -0.52 -9.35 -0.45 1.15e-18 Lung cancer; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23396286 chr10:99258505 UBTD1;MMS19 0.4 6.45 0.33 3.77e-10 Cognitive function; LIHC cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.58 8.61 0.42 2.66e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg06481639 chr22:41940642 POLR3H 0.6 5.77 0.3 1.81e-8 Vitiligo; LIHC cis rs9611519 0.780 rs9611546 chr22:41698542 C/G cg03806693 chr22:41940476 POLR3H -0.77 -9.2 -0.45 3.63e-18 Neuroticism; LIHC cis rs3806843 0.966 rs2337516 chr5:140140853 A/G cg26395211 chr5:140044315 WDR55 0.41 6.01 0.31 4.69e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg03466237 chr11:1298256 TOLLIP 0.44 6.73 0.34 7.19e-11 Alopecia areata; LIHC cis rs2075165 0.901 rs1043165 chr1:156220056 T/C cg10096929 chr1:156261403 TMEM79 0.37 6.03 0.31 4.36e-9 Tonsillectomy; LIHC cis rs238295 0.805 rs6053527 chr20:5582457 G/T cg24001556 chr20:5591874 RP5-1022P6.2 -0.51 -6.91 -0.35 2.44e-11 Occipital cortical area (total cortical area interaction); LIHC cis rs7264396 0.563 rs2066066 chr20:34329359 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.68 -0.43 1.59e-16 Total cholesterol levels; LIHC cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg18867708 chr6:26865862 GUSBL1 -0.56 -8.6 -0.42 2.82e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg17691542 chr6:26056736 HIST1H1C 0.43 5.91 0.3 8.33e-9 Blood metabolite levels; LIHC cis rs9303401 0.614 rs12947982 chr17:57140301 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.83 0.54 2.66e-27 Cognitive test performance; LIHC cis rs11628318 0.614 rs3783383 chr14:103177420 G/C cg23461800 chr14:103021989 NA 0.41 6.14 0.32 2.24e-9 Platelet count; LIHC trans rs1814175 0.616 rs1722020 chr11:49904189 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg18252515 chr7:66147081 NA 1.3 16.83 0.67 1.01e-46 Diabetic kidney disease; LIHC cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg20887711 chr4:1340912 KIAA1530 0.5 7.86 0.39 5.08e-14 Obesity-related traits; LIHC trans rs6489882 0.836 rs10850099 chr12:113364504 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6.02e-10 Chronic lymphocytic leukemia; LIHC cis rs9486715 0.830 rs1475748 chr6:97034143 T/C cg18709589 chr6:96969512 KIAA0776 -0.34 -5.99 -0.31 5.31e-9 Headache; LIHC cis rs7618501 1.000 rs35261599 chr3:49773236 G/A cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC cis rs17539620 0.519 rs12665532 chr6:154835182 C/G cg17771515 chr6:154831774 CNKSR3 0.54 6.14 0.32 2.25e-9 Lipoprotein (a) levels; LIHC cis rs11098499 0.604 rs2389887 chr4:120570644 T/C cg09307838 chr4:120376055 NA 0.66 9.71 0.46 7.89e-20 Corneal astigmatism; LIHC cis rs2153535 0.580 rs1335637 chr6:8465101 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19584341 chr11:506908 RNH1 -0.45 -6.78 -0.34 5.42e-11 Pancreatic cancer; LIHC cis rs6831352 1.000 rs6822348 chr4:100053894 A/T cg12011299 chr4:100065546 ADH4 0.57 10.09 0.48 4.04e-21 Alcohol dependence; LIHC cis rs4268898 0.679 rs2551181 chr2:24437548 C/T cg06627628 chr2:24431161 ITSN2 0.64 8.61 0.42 2.65e-16 Asthma; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg09310383 chr3:37218128 LRRFIP2 -0.51 -6.34 -0.32 7.46e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs782590 0.837 rs782584 chr2:55921116 C/G cg03859395 chr2:55845619 SMEK2 -0.86 -14.66 -0.62 4.25e-38 Metabolic syndrome; LIHC cis rs600626 0.636 rs11236515 chr11:75451411 A/G cg24262691 chr11:75473276 NA 0.4 5.88 0.3 9.5e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs7829975 0.711 rs4841051 chr8:8685646 C/T cg06636001 chr8:8085503 FLJ10661 -0.41 -6.51 -0.33 2.72e-10 Mood instability; LIHC cis rs6808694 0.568 rs17006711 chr3:20228005 C/T cg00235661 chr3:20228976 SGOL1 0.38 6.67 0.34 1.02e-10 Ischemic stroke; LIHC cis rs4862750 0.914 rs11943333 chr4:187872455 A/G cg11301795 chr4:187892539 NA -0.27 -7.48 -0.38 6.16e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs9290065 0.585 rs716779 chr3:160645428 G/A cg03342759 chr3:160939853 NMD3 0.6 8.14 0.4 7.31e-15 Kawasaki disease; LIHC trans rs75804782 0.521 rs72993065 chr2:239409001 C/T cg01134436 chr17:81009848 B3GNTL1 0.83 6.91 0.35 2.39e-11 Morning vs. evening chronotype;Chronotype; LIHC trans rs7142002 1.000 rs7145940 chr14:102361134 G/A cg18984499 chr17:8286166 RPL26 0.65 6.14 0.32 2.3e-9 Autism; LIHC cis rs853679 0.517 rs9368553 chr6:28082265 T/C cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs826838 0.967 rs11183622 chr12:38792849 T/C cg13010199 chr12:38710504 ALG10B 0.65 7.82 0.39 6.73e-14 Heart rate; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs4742903 1.000 rs4742906 chr9:106857078 A/G cg14250997 chr9:106856677 SMC2 0.43 7.37 0.37 1.32e-12 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs1814175 0.571 rs12294066 chr11:49738287 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.94 0.35 1.94e-11 Height; LIHC cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg22800045 chr5:56110881 MAP3K1 0.67 8.53 0.42 4.8e-16 Initial pursuit acceleration; LIHC cis rs9303401 0.573 rs34097494 chr17:57171917 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 9.02 0.44 1.39e-17 Cognitive test performance; LIHC trans rs2243480 1.000 rs2961102 chr7:65424658 A/G cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs950169 0.881 rs34591918 chr15:84950833 C/T cg03959625 chr15:84868606 LOC388152 0.47 6.76 0.34 6.14e-11 Schizophrenia; LIHC cis rs7833986 0.534 rs17813240 chr8:56925791 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.82 8.3 0.41 2.48e-15 Height; LIHC cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.9 -10.81 -0.5 1.26e-23 Platelet count; LIHC cis rs988712 0.622 rs4922793 chr11:27729505 A/G cg18117895 chr11:27722066 BDNF 0.5 6.92 0.35 2.2e-11 Obesity; LIHC cis rs600806 0.778 rs4970761 chr1:109995398 C/T cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.61 -0.38 2.77e-13 Intelligence (multi-trait analysis); LIHC cis rs2070433 0.756 rs9637220 chr21:47887436 T/C cg12379764 chr21:47803548 PCNT 0.61 8.84 0.43 5.2e-17 Lymphocyte counts; LIHC cis rs769267 0.930 rs4808208 chr19:19650096 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.71 0.3 2.42e-8 Tonsillectomy; LIHC cis rs9300255 0.602 rs1051431 chr12:123645803 G/A cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs74544699 1.000 rs7666671 chr4:74807007 G/A cg02530824 chr4:74847766 PF4 0.62 6.45 0.33 3.77e-10 Growth-regulated protein alpha levels; LIHC cis rs8114671 0.585 rs2236271 chr20:33523840 G/T cg07148914 chr20:33460835 GGT7 -0.65 -9.91 -0.47 1.57e-20 Height; LIHC cis rs712039 0.652 rs853222 chr17:35790022 G/T cg16670864 chr17:35848621 DUSP14 0.34 5.73 0.3 2.16e-8 Tuberculosis; LIHC cis rs1707322 0.721 rs4431884 chr1:46101323 C/T cg06784218 chr1:46089804 CCDC17 0.4 7.58 0.38 3.39e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7493 0.901 rs17883318 chr7:94958312 G/A cg21856205 chr7:94953877 PON1 -0.43 -5.91 -0.3 8.47e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs875971 0.660 rs7807930 chr7:66087165 C/T cg11764359 chr7:65958608 NA -0.72 -10.77 -0.5 1.73e-23 Aortic root size; LIHC cis rs1448094 0.512 rs7313278 chr12:86250263 C/T cg02569458 chr12:86230093 RASSF9 0.46 6.19 0.32 1.76e-9 Major depressive disorder; LIHC cis rs600806 0.850 rs3768493 chr1:109935505 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs1538970 0.781 rs34768551 chr1:46020408 G/A cg05343316 chr1:45956843 TESK2 0.59 7.79 0.39 7.91e-14 Platelet count; LIHC cis rs6545883 0.894 rs2463102 chr2:61571295 G/C cg15711740 chr2:61764176 XPO1 0.43 5.88 0.3 9.65e-9 Tuberculosis; LIHC cis rs2932538 0.883 rs7549547 chr1:113086717 A/T cg22162597 chr1:113214053 CAPZA1 0.7 10.71 0.5 2.76e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs9470366 0.545 rs4711457 chr6:36633160 T/C cg08179530 chr6:36648295 CDKN1A -0.6 -9.11 -0.44 7.08e-18 QRS duration; LIHC cis rs6582630 0.555 rs10880607 chr12:38508184 A/G cg26384229 chr12:38710491 ALG10B 0.96 12.69 0.57 1.68e-30 Drug-induced liver injury (flucloxacillin); LIHC trans rs10411161 0.702 rs8113768 chr19:52383938 C/T cg22319618 chr22:45562946 NUP50 -0.6 -8.17 -0.4 6.12e-15 Breast cancer; LIHC cis rs858239 0.601 rs6971002 chr7:23172304 C/G cg23682824 chr7:23144976 KLHL7 0.42 6.31 0.32 8.83e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.89 0.3 9.31e-9 Tonsillectomy; LIHC cis rs9790314 1.000 rs336577 chr3:161066294 C/T cg03342759 chr3:160939853 NMD3 -0.7 -8.42 -0.41 1.07e-15 Morning vs. evening chronotype; LIHC cis rs6596100 0.538 rs4705972 chr5:132179237 T/A cg02081065 chr5:132209139 LEAP2 0.3 6.38 0.33 5.75e-10 Breast cancer; LIHC cis rs428668 0.523 rs6898671 chr5:150677643 A/T cg14086364 chr5:150678334 SLC36A3 0.28 7.45 0.37 7.61e-13 Skin aging (microtopography measurement); LIHC cis rs611744 0.967 rs684093 chr8:109199355 G/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs7264396 1.000 rs224437 chr20:34154371 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.85 -0.35 3.44e-11 Total cholesterol levels; LIHC trans rs1814175 0.645 rs847630 chr11:49926360 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs66569888 0.789 rs17213078 chr2:106734065 G/A cg23109721 chr2:106886537 NA -0.65 -6.29 -0.32 9.47e-10 Facial morphology (factor 23); LIHC cis rs7927771 0.929 rs12787646 chr11:47669665 T/C cg20135002 chr11:47629003 NA -0.53 -9.09 -0.44 8.16e-18 Subjective well-being; LIHC cis rs7412746 0.658 rs897815 chr1:150879101 C/T cg15448220 chr1:150897856 SETDB1 -0.42 -6.79 -0.34 5.06e-11 Melanoma; LIHC cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg20607798 chr8:58055168 NA 0.65 8.02 0.4 1.64e-14 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.618 rs6943788 chr7:139087697 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs72627123 0.867 rs73303135 chr14:74495090 C/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.78 0.3 1.64e-8 Morning vs. evening chronotype; LIHC cis rs2257205 0.667 rs8080281 chr17:56938558 A/G cg12560992 chr17:57184187 TRIM37 -0.66 -7.18 -0.36 4.32e-12 Pancreatic cancer; LIHC cis rs12611088 0.600 rs2355994 chr19:44005107 T/C cg13740135 chr19:44006432 PHLDB3 -0.42 -6.16 -0.32 2.03e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs9914988 0.943 rs4795457 chr17:27087929 C/T cg20469991 chr17:27169893 C17orf63 -0.58 -6.8 -0.34 4.8e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg03264133 chr6:25882463 NA -0.94 -13.55 -0.59 8.86e-34 Blood metabolite levels; LIHC trans rs1814175 0.817 rs1851858 chr11:49855638 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.42e-11 Height; LIHC cis rs829661 0.947 rs829665 chr2:30724701 T/A cg12454169 chr2:30669597 LCLAT1 0.77 7.45 0.37 7.5e-13 Midgestational circulating levels of PBDEs (fetal genetic effect); LIHC cis rs1552244 0.882 rs13099507 chr3:10031603 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.58 -8.19 -0.4 5.24e-15 Alzheimer's disease; LIHC cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg08888203 chr3:10149979 C3orf24 0.5 6.06 0.31 3.53e-9 Alzheimer's disease; LIHC cis rs921968 0.643 rs3845836 chr2:219504955 C/T cg02985541 chr2:219472218 PLCD4 0.41 7.56 0.38 3.86e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7044106 0.791 rs4617229 chr9:123480696 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.63 0.5 5.57e-23 Hip circumference adjusted for BMI; LIHC cis rs11628318 0.713 rs4900543 chr14:103029024 T/C cg01864069 chr14:103024347 NA -0.58 -9.5 -0.46 3.83e-19 Platelet count; LIHC cis rs9322817 1.000 rs6900902 chr6:105235757 A/G cg02098413 chr6:105308735 HACE1 -0.37 -6.01 -0.31 4.87e-9 Thyroid stimulating hormone; LIHC trans rs2727020 0.658 rs7120136 chr11:49384358 A/C cg18944383 chr4:111397179 ENPEP 0.26 6.34 0.32 7.06e-10 Coronary artery disease; LIHC cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg05564831 chr3:52568323 NT5DC2 0.38 6.18 0.32 1.83e-9 Bipolar disorder; LIHC cis rs36051895 0.632 rs1328919 chr9:5166548 C/T cg02405213 chr9:5042618 JAK2 -0.75 -11.92 -0.54 1.27e-27 Pediatric autoimmune diseases; LIHC cis rs9911578 1.000 rs437732 chr17:56675861 A/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs782590 0.620 rs7596377 chr2:55888612 T/A cg03859395 chr2:55845619 SMEK2 -0.56 -9.32 -0.45 1.49e-18 Metabolic syndrome; LIHC cis rs9948 0.786 rs72809850 chr2:97449762 A/C cg01990225 chr2:97406019 LMAN2L -0.73 -6.31 -0.32 8.85e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg13047869 chr3:10149882 C3orf24 -0.48 -5.95 -0.31 6.52e-9 Alzheimer's disease; LIHC cis rs57221529 0.766 rs17497684 chr5:558307 T/C cg09021430 chr5:549028 NA -0.46 -9.13 -0.44 5.9e-18 Lung disease severity in cystic fibrosis; LIHC cis rs7707921 0.881 rs112355050 chr5:81386035 C/T cg15871215 chr5:81402204 ATG10 -0.61 -5.95 -0.31 6.55e-9 Breast cancer; LIHC cis rs2549003 0.674 rs960757 chr5:131826310 G/A cg02551604 chr5:131831745 NA -0.5 -7.48 -0.37 6.53e-13 Asthma (sex interaction); LIHC cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg13393036 chr8:95962371 TP53INP1 -0.39 -8.8 -0.43 6.72e-17 Type 2 diabetes; LIHC cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg15691649 chr6:25882328 NA 0.52 7.73 0.39 1.24e-13 Blood metabolite levels; LIHC cis rs12893668 0.572 rs4906356 chr14:104138701 C/T cg24130564 chr14:104152367 KLC1 -0.55 -9.5 -0.46 3.67e-19 Reticulocyte count; LIHC cis rs4423214 1.000 rs4944946 chr11:71159429 G/A cg24826892 chr11:71159390 DHCR7 0.56 7.13 0.36 5.91e-12 Vitamin D levels; LIHC cis rs7712401 0.791 rs6595409 chr5:122113756 G/A cg18764291 chr5:122110994 SNX2 0.35 5.94 0.31 7.13e-9 Mean platelet volume; LIHC cis rs7078219 0.505 rs10883367 chr10:101287990 A/G cg06854084 chr10:101292507 NKX2-3 -0.33 -6.17 -0.32 1.97e-9 Dental caries; LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs78456975 0.550 rs11904276 chr2:1524006 T/C cg01028140 chr2:1542097 TPO -0.41 -6.53 -0.33 2.36e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs17685 0.753 rs1104878 chr7:75685593 G/T cg04592579 chr7:75616294 TMEM120A 0.4 7.0 0.35 1.32e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.49 0.42 6.5e-16 Platelet count; LIHC cis rs4819052 0.851 rs2236443 chr21:46678174 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.9 0.51 5.81e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs66887589 0.934 rs56843000 chr4:120516597 T/C cg09307838 chr4:120376055 NA -0.48 -7.29 -0.37 2.11e-12 Diastolic blood pressure; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg00280220 chr17:61926910 NA 0.4 6.46 0.33 3.69e-10 Prudent dietary pattern; LIHC cis rs523522 0.962 rs7471 chr12:120941215 T/C cg12219531 chr12:120966889 COQ5 0.67 13.2 0.58 2e-32 High light scatter reticulocyte count; LIHC cis rs333960 0.597 rs333962 chr1:110440117 C/T cg09167608 chr1:110449308 NA 0.42 5.88 0.3 9.59e-9 Obesity-related traits; LIHC cis rs6430585 0.527 rs961360 chr2:136393658 A/G cg07169764 chr2:136633963 MCM6 0.63 8.11 0.4 9.21e-15 Corneal structure; LIHC cis rs2422052 0.639 rs1433531 chr2:118646201 A/C cg22545206 chr2:118617499 NA 0.36 6.08 0.31 3.19e-9 Mosquito bite size; LIHC cis rs7615952 0.576 rs1127717 chr3:125826059 T/C cg05084668 chr3:125655381 ALG1L -0.39 -6.0 -0.31 5.01e-9 Blood pressure (smoking interaction); LIHC cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.3 -0.45 1.65e-18 Bipolar disorder; LIHC cis rs9303401 0.659 rs34275691 chr17:56736640 A/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs1023500 0.505 rs134889 chr22:42674350 A/T cg04733989 chr22:42467013 NAGA 0.42 6.3 0.32 9.14e-10 Schizophrenia; LIHC cis rs7572733 0.534 rs6760891 chr2:198768166 T/G cg00792783 chr2:198669748 PLCL1 0.47 6.95 0.35 1.9e-11 Dermatomyositis; LIHC cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg06634786 chr22:41940651 POLR3H -0.76 -8.05 -0.4 1.34e-14 Vitiligo; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg07677032 chr17:61819896 STRADA 0.43 5.98 0.31 5.56e-9 Prudent dietary pattern; LIHC cis rs7824557 0.592 rs2572371 chr8:11223793 G/T cg21775007 chr8:11205619 TDH 0.6 8.8 0.43 7.07e-17 Retinal vascular caliber; LIHC cis rs7659604 0.502 rs13104233 chr4:122672473 T/C cg19671926 chr4:122722719 EXOSC9 0.47 6.96 0.35 1.78e-11 Type 2 diabetes; LIHC cis rs6831256 1.000 rs6831256 chr4:3473139 A/G cg23495837 chr4:3480318 DOK7 -0.37 -6.75 -0.34 6.25e-11 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs7767926 chr6:8453557 A/G cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.77e-28 Motion sickness; LIHC cis rs2439831 1.000 rs2584726 chr15:43715382 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.78 13.43 0.59 2.61e-33 Lung cancer in ever smokers; LIHC trans rs1814175 0.817 rs11518158 chr11:49985633 G/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 4.76e-74 Height; LIHC cis rs4819052 0.808 rs2246697 chr21:46689999 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.26 0.41 3.32e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs116095464 0.558 rs10043002 chr5:226753 G/A cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs2637030 0.559 rs923609 chr5:52912249 G/A cg06476337 chr5:52856530 NDUFS4 0.42 6.35 0.32 7.02e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs17685 0.712 rs59659102 chr7:75710114 G/A cg04610667 chr7:75704037 NA -0.33 -6.0 -0.31 5.08e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9393777 0.513 rs9368450 chr6:26652489 A/C cg12826209 chr6:26865740 GUSBL1 0.57 5.92 0.3 8.01e-9 Intelligence (multi-trait analysis); LIHC cis rs4699052 0.963 rs7679365 chr4:104212980 G/C cg16532752 chr4:104119610 CENPE -0.39 -6.29 -0.32 9.82e-10 Testicular germ cell tumor; LIHC cis rs7937890 0.869 rs2915404 chr11:14404825 A/G cg02886208 chr11:14281011 SPON1 -0.5 -7.14 -0.36 5.66e-12 Mitochondrial DNA levels; LIHC cis rs5770917 1.000 rs762676 chr22:51017794 A/G cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.44 -6.44 -0.33 4.11e-10 Narcolepsy; LIHC cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.06 11.57 0.53 2.37e-26 Platelet count; LIHC cis rs9612 0.948 rs12609056 chr19:44258702 G/T cg08581076 chr19:44259116 C19orf61 0.69 8.87 0.43 4.09e-17 Exhaled nitric oxide output; LIHC cis rs7633770 0.664 rs11130101 chr3:46685895 T/A cg11219411 chr3:46661640 NA -0.35 -5.78 -0.3 1.66e-8 Coronary artery disease; LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs1949733 1.000 rs1949733 chr4:8503359 C/T cg11789530 chr4:8429930 ACOX3 -0.75 -11.5 -0.53 4.41e-26 Response to antineoplastic agents; LIHC cis rs2836974 0.545 rs3167757 chr21:40714478 C/T cg11890956 chr21:40555474 PSMG1 0.58 8.66 0.42 1.91e-16 Cognitive function; LIHC cis rs9549367 0.789 rs12866090 chr13:113869410 G/A cg00898013 chr13:113819073 PROZ -0.41 -7.22 -0.36 3.49e-12 Platelet distribution width; LIHC trans rs1814175 0.781 rs2866734 chr11:49886338 A/G cg15704280 chr7:45808275 SEPT13 -1.01 -23.35 -0.78 8.99e-73 Height; LIHC cis rs6964587 1.000 rs6956431 chr7:91750016 T/C cg17063962 chr7:91808500 NA 1.01 19.45 0.72 2.9e-57 Breast cancer; LIHC cis rs12142240 0.698 rs10158572 chr1:46822440 G/T cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs9733 0.818 rs7520022 chr1:150659173 C/G cg17724175 chr1:150552817 MCL1 -0.36 -7.62 -0.38 2.51e-13 Tonsillectomy; LIHC cis rs919433 0.679 rs55656916 chr2:198519628 T/C cg10820045 chr2:198174542 NA 0.47 7.44 0.37 7.99e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00365505 chr7:150066001 REPIN1 -0.47 -7.17 -0.36 4.74e-12 Cognitive function; LIHC cis rs832187 0.593 rs3774713 chr3:63917692 G/C cg16258503 chr3:63850278 ATXN7;THOC7 -0.45 -6.27 -0.32 1.06e-9 Schizophrenia; LIHC cis rs11628318 0.515 rs7152144 chr14:103126101 C/T cg12046867 chr14:103022105 NA 0.43 6.62 0.34 1.36e-10 Platelet count; LIHC cis rs2153535 0.580 rs4451187 chr6:8473910 C/T cg07606381 chr6:8435919 SLC35B3 0.82 12.26 0.55 6.73e-29 Motion sickness; LIHC cis rs6831352 0.918 rs29001216 chr4:100051556 A/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7208859 0.673 rs57432042 chr17:29241038 T/C cg13385521 chr17:29058706 SUZ12P 0.75 7.06 0.36 9.39e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10870270 0.917 rs11146417 chr10:133791034 C/G cg26149184 chr10:133730230 NA 0.49 7.59 0.38 3.13e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs950169 0.840 rs62019457 chr15:85102142 T/C cg12863693 chr15:85201151 NMB 0.43 6.09 0.31 3.07e-9 Schizophrenia; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg09367891 chr1:107599246 PRMT6 0.68 11.04 0.51 1.93e-24 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs11098499 0.863 rs11723090 chr4:120490592 T/C cg25214090 chr10:38739885 LOC399744 0.58 9.49 0.46 3.93e-19 Corneal astigmatism; LIHC cis rs1801251 0.778 rs809639 chr2:233731244 C/G cg08000102 chr2:233561755 GIGYF2 0.71 10.58 0.5 8.25e-23 Coronary artery disease; LIHC cis rs2425143 1.000 rs7261284 chr20:34244104 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.84 -0.3 1.2e-8 Blood protein levels; LIHC cis rs72781680 0.644 rs72783627 chr2:24315685 A/C cg06627628 chr2:24431161 ITSN2 -0.65 -7.6 -0.38 2.84e-13 Lymphocyte counts; LIHC cis rs3796352 1.000 rs36090694 chr3:53010742 T/C cg04865290 chr3:52927548 TMEM110 -0.51 -5.73 -0.3 2.2e-8 Immune reponse to smallpox (secreted IL-2); LIHC cis rs6952808 0.792 rs12531315 chr7:1953650 C/G cg04267008 chr7:1944627 MAD1L1 -0.72 -11.65 -0.53 1.21e-26 Bipolar disorder and schizophrenia; LIHC cis rs910316 0.737 rs424120 chr14:75482828 G/T cg08847533 chr14:75593920 NEK9 -0.88 -18.1 -0.7 8.06e-52 Height; LIHC cis rs11758351 0.715 rs76130408 chr6:26208962 A/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.26 0.37 2.59e-12 Gout;Renal underexcretion gout; LIHC cis rs344364 0.511 rs1657132 chr16:1949924 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs992157 0.798 rs10206064 chr2:219157959 T/C cg20019365 chr2:219134978 PNKD;AAMP 0.78 12.51 0.56 8.22e-30 Colorectal cancer; LIHC cis rs7572733 0.515 rs1356542 chr2:198835702 G/T cg00792783 chr2:198669748 PLCL1 0.45 6.6 0.34 1.52e-10 Dermatomyositis; LIHC cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg24884572 chr19:58661833 ZNF329 0.98 7.8 0.39 7.58e-14 Cholesterol, total; LIHC cis rs7098414 0.511 rs7071752 chr10:82159539 C/A cg00277334 chr10:82204260 NA -0.61 -10.04 -0.48 5.84e-21 Post bronchodilator FEV1; LIHC cis rs11663156 0.804 rs4940255 chr18:50907179 C/A cg24270629 chr18:50823537 DCC -0.56 -7.88 -0.39 4.36e-14 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg24209194 chr3:40518798 ZNF619 -0.6 -9.3 -0.45 1.68e-18 Renal cell carcinoma; LIHC cis rs4789452 0.655 rs2001613 chr17:75383679 C/T cg06761530 chr17:75373219 SEPT9 -0.47 -6.12 -0.31 2.62e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs10949834 0.838 rs1091811 chr7:73491212 A/G cg07137043 chr7:73588983 EIF4H 0.56 6.05 0.31 3.8e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg04944784 chr2:26401820 FAM59B 0.72 9.21 0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs2274273 0.840 rs17674463 chr14:55824863 A/T cg01864836 chr14:55583639 NA -0.37 -6.62 -0.34 1.36e-10 Protein biomarker; LIHC cis rs12142240 0.698 rs112068407 chr1:46822291 T/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs56011263 0.687 rs4690186 chr4:703607 G/A cg20735989 chr4:730612 PCGF3 -0.67 -8.72 -0.43 1.19e-16 White blood cell count; LIHC cis rs9419702 0.568 rs7920966 chr10:133555185 G/T cg20568497 chr10:133558893 NA 0.42 6.55 0.33 2.09e-10 Survival in rectal cancer; LIHC cis rs35110281 0.714 rs7277539 chr21:45053011 A/G cg01579765 chr21:45077557 HSF2BP -0.36 -6.95 -0.35 1.87e-11 Mean corpuscular volume; LIHC trans rs3813567 0.759 rs7163204 chr15:78953740 G/A cg24133106 chr7:129690864 ZC3HC1 -0.49 -6.1 -0.31 2.85e-9 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; LIHC cis rs2580764 0.515 rs7570629 chr2:55255935 A/T cg09592903 chr2:55203963 RTN4 -0.73 -13.47 -0.59 1.87e-33 Mean platelet volume; LIHC cis rs1005277 0.579 rs1780121 chr10:38529437 C/A cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.9 -0.3 8.56e-9 Extrinsic epigenetic age acceleration; LIHC cis rs56235845 0.694 rs11738681 chr5:176761535 A/G cg06060754 chr5:176797920 RGS14 0.47 6.52 0.33 2.53e-10 Hemoglobin concentration;Hematocrit; LIHC cis rs2455799 0.613 rs2470549 chr3:15737698 T/C cg12698662 chr3:15914712 MIR563 -0.36 -6.57 -0.33 1.87e-10 Mean platelet volume; LIHC cis rs9633740 0.685 rs4934284 chr10:82277297 C/G cg01528321 chr10:82214614 TSPAN14 -0.85 -6.99 -0.35 1.41e-11 Post bronchodilator FEV1; LIHC cis rs7833986 0.534 rs2976022 chr8:57007843 T/G cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.06e-16 Height; LIHC cis rs4474465 0.790 rs7481910 chr11:78264202 G/C cg27205649 chr11:78285834 NARS2 0.43 6.49 0.33 3.01e-10 Alzheimer's disease (survival time); LIHC trans rs3812049 0.784 rs3749748 chr5:127350549 C/T cg16011800 chr17:1958478 HIC1 0.5 7.06 0.36 9.16e-12 Lymphocyte counts;Red cell distribution width; LIHC cis rs12479064 0.724 rs6748200 chr2:100080895 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.6 -7.49 -0.38 6.08e-13 Chronic sinus infection; LIHC cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg25364880 chr3:44379878 C3orf23 0.6 8.46 0.42 8.16e-16 Depressive symptoms; LIHC trans rs783540 0.934 rs1594511 chr15:83307063 T/A cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.63 -0.34 1.32e-10 Schizophrenia; LIHC cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 -0.54 -8.0 -0.4 1.91e-14 Age at first birth; LIHC cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7666738 0.512 rs1648536 chr4:99019881 G/T cg05340658 chr4:99064831 C4orf37 -0.41 -6.32 -0.32 8.35e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs11971779 0.648 rs59791374 chr7:139116962 C/T cg07862535 chr7:139043722 LUC7L2 0.6 10.39 0.49 3.67e-22 Diisocyanate-induced asthma; LIHC trans rs4650994 0.524 rs1998544 chr1:178605276 T/C cg05059571 chr16:84539110 KIAA1609 0.4 6.74 0.34 6.73e-11 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1005277 0.541 rs2263163 chr10:38389887 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3736485 0.934 rs17609693 chr15:51868000 T/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1.02e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs12893668 0.644 rs12890820 chr14:104034849 T/C cg19000871 chr14:103996768 TRMT61A -0.41 -6.72 -0.34 7.68e-11 Reticulocyte count; LIHC cis rs2463822 1.000 rs1881534 chr11:62085083 A/G cg06239285 chr11:62104954 ASRGL1 0.97 7.08 0.36 8.01e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs11719291 0.833 rs11715835 chr3:48770732 C/T cg06212747 chr3:49208901 KLHDC8B -0.66 -5.89 -0.3 9.27e-9 Cognitive function; LIHC cis rs7937890 1.000 rs7937890 chr11:14396485 C/T cg23387056 chr11:14280742 SPON1 -0.42 -5.87 -0.3 1.05e-8 Mitochondrial DNA levels; LIHC cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg06481639 chr22:41940642 POLR3H -0.71 -7.09 -0.36 7.81e-12 Vitiligo; LIHC cis rs11628318 0.614 rs942022 chr14:103108842 C/T cg23461800 chr14:103021989 NA -0.47 -6.65 -0.34 1.13e-10 Platelet count; LIHC cis rs3741404 0.609 rs651855 chr11:63870810 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 10.94 0.51 4.19e-24 Platelet count; LIHC cis rs769267 0.895 rs2965189 chr19:19519518 G/T cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.88 0.3 9.64e-9 Tonsillectomy; LIHC cis rs5769765 0.542 rs1535189 chr22:50249131 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.57 5.79 0.3 1.62e-8 Schizophrenia; LIHC cis rs10463316 0.832 rs246483 chr5:150731062 C/G cg03212797 chr5:150827313 SLC36A1 -0.47 -7.04 -0.36 1.09e-11 Metabolite levels (Pyroglutamine); LIHC cis rs1005277 0.579 rs2474595 chr10:38426782 C/G cg25427524 chr10:38739819 LOC399744 0.66 12.63 0.56 2.77e-30 Extrinsic epigenetic age acceleration; LIHC cis rs17685 0.672 rs55807301 chr7:75807401 C/A cg04592579 chr7:75616294 TMEM120A 0.4 6.86 0.35 3.3e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7487075 0.619 rs7134289 chr12:46838336 G/A cg23829395 chr12:46796953 NA 0.34 6.05 0.31 3.81e-9 Itch intensity from mosquito bite; LIHC cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg11905131 chr22:24372483 LOC391322 -0.68 -9.98 -0.47 9.55e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg25951256 chr10:38645740 HSD17B7P2 -0.39 -5.78 -0.3 1.69e-8 Extrinsic epigenetic age acceleration; LIHC cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg24004478 chr7:855632 UNC84A 0.48 7.95 0.39 2.84e-14 Perceived unattractiveness to mosquitoes; LIHC cis rs7712401 0.720 rs12109791 chr5:122146831 C/T cg18764291 chr5:122110994 SNX2 0.36 6.09 0.31 2.99e-9 Mean platelet volume; LIHC cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg10560079 chr2:191398806 TMEM194B 0.51 7.93 0.39 3.2e-14 Pulse pressure; LIHC cis rs7312933 0.703 rs12371615 chr12:42563989 C/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.82 0.39 6.63e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2274273 0.840 rs11547116 chr14:55738165 T/C cg01864836 chr14:55583639 NA -0.4 -7.37 -0.37 1.27e-12 Protein biomarker; LIHC cis rs3845702 0.736 rs6433821 chr2:180837806 T/A cg01881094 chr2:180872142 CWC22 -1.14 -10.1 -0.48 3.66e-21 Schizophrenia; LIHC trans rs1814175 0.616 rs10839388 chr11:49842603 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.91 0.35 2.33e-11 Height; LIHC cis rs2841277 0.708 rs10083490 chr14:105402418 A/G cg21017887 chr14:105400489 NA -0.64 -12.53 -0.56 6.8e-30 Rheumatoid arthritis; LIHC cis rs6570726 0.791 rs9497357 chr6:145912888 G/A cg13319975 chr6:146136371 FBXO30 -0.37 -5.86 -0.3 1.12e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs12142240 0.698 rs72679807 chr1:46846490 G/A cg00530320 chr1:46809349 NSUN4 0.53 5.78 0.3 1.68e-8 Menopause (age at onset); LIHC trans rs3780486 0.718 rs3818593 chr9:33120706 A/G cg04842962 chr6:43655489 MRPS18A 0.86 13.39 0.59 3.5e-33 IgG glycosylation; LIHC cis rs67311347 0.955 rs4973999 chr3:40460383 G/A cg00656387 chr3:40428638 ENTPD3 0.44 7.46 0.37 7.03e-13 Renal cell carcinoma; LIHC cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg15691649 chr6:25882328 NA -0.63 -8.11 -0.4 8.88e-15 Intelligence (multi-trait analysis); LIHC cis rs6665290 0.901 rs2104860 chr1:227208637 G/C cg10327440 chr1:227177885 CDC42BPA -1.12 -22.14 -0.77 5.02e-68 Myeloid white cell count; LIHC cis rs74181299 0.890 rs2723062 chr2:65280220 G/A cg05010058 chr2:65284262 CEP68 0.41 6.91 0.35 2.31e-11 Pulse pressure; LIHC cis rs12142240 0.698 rs68191463 chr1:46808695 T/C cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC trans rs867371 1.000 rs7180584 chr15:82455834 A/G cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.37 -0.33 6.01e-10 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7666738 0.830 rs28515641 chr4:98726419 G/A cg05340658 chr4:99064831 C4orf37 0.64 11.61 0.53 1.65e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2292096 1.000 rs16847183 chr1:200731955 A/C cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.12 -0.31 2.57e-9 Epilepsy; LIHC cis rs5769765 0.773 rs138834 chr22:50180497 A/C cg02269571 chr22:50332266 NA -0.74 -8.91 -0.43 3.1e-17 Schizophrenia; LIHC cis rs4819052 0.788 rs2236449 chr21:46702506 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.65 9.2 0.45 3.64e-18 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12908161 1.000 rs36033486 chr15:85319692 A/G cg12863693 chr15:85201151 NMB 0.44 6.34 0.32 7.18e-10 Schizophrenia; LIHC cis rs1707322 0.963 rs34907901 chr1:46405214 T/G cg06784218 chr1:46089804 CCDC17 0.33 5.91 0.3 8.5e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg21724239 chr8:58056113 NA 0.57 7.5 0.38 5.53e-13 Developmental language disorder (linguistic errors); LIHC cis rs17376456 0.569 rs6879620 chr5:93119893 G/A cg25358565 chr5:93447407 FAM172A -0.79 -7.65 -0.38 2.1e-13 Diabetic retinopathy; LIHC cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg19318889 chr4:1322082 MAEA -0.69 -10.69 -0.5 3.4e-23 Longevity; LIHC cis rs7726839 0.540 rs61580655 chr5:597564 A/G cg09021430 chr5:549028 NA -0.42 -8.44 -0.42 9.17e-16 Obesity-related traits; LIHC cis rs7572733 0.534 rs4369854 chr2:198800630 T/C cg03934865 chr2:198174659 NA 0.46 6.79 0.34 5.08e-11 Dermatomyositis; LIHC cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg22105103 chr4:187893119 NA 0.35 8.82 0.43 6.11e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs7312933 0.558 rs4768411 chr12:42855390 A/G cg01256987 chr12:42539512 GXYLT1 0.34 5.79 0.3 1.63e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9916302 0.904 rs11078898 chr17:37536480 A/G cg07936489 chr17:37558343 FBXL20 0.85 13.75 0.6 1.49e-34 Glomerular filtration rate (creatinine); LIHC cis rs9303401 0.580 rs2013166 chr17:56637630 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs7216064 1.000 rs12452511 chr17:65832576 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.33 -0.45 1.36e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6138458 0.626 rs6050259 chr20:25011423 A/G cg26195577 chr20:24973756 C20orf3 0.72 8.97 0.44 1.96e-17 Blood protein levels; LIHC cis rs2010672 0.500 rs4932351 chr15:91143720 C/G cg26821196 chr15:91095069 CRTC3 0.32 5.99 0.31 5.4e-9 Sum eosinophil basophil counts;Eosinophil percentage of white cells;Eosinophil counts; LIHC cis rs9328573 1.000 rs9920482 chr15:100510477 A/G cg09918751 chr15:100517450 ADAMTS17 -0.49 -7.55 -0.38 3.93e-13 Urate levels in lean individuals; LIHC cis rs315122 0.588 rs548240 chr12:69756291 A/T cg14784868 chr12:69753453 YEATS4 0.61 5.76 0.3 1.89e-8 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs4478037 0.822 rs4320035 chr3:33113697 C/G cg27203090 chr3:33138513 GLB1;TMPPE 0.57 7.08 0.36 8.28e-12 Major depressive disorder; LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.715 rs10839409 chr11:49884647 G/T cg18944383 chr4:111397179 ENPEP 0.27 7.06 0.36 9.16e-12 Height; LIHC cis rs936229 0.813 rs4886619 chr15:75106138 C/T cg14664628 chr15:75095509 CSK -1.01 -21.15 -0.75 4.3e-64 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs1801251 1.000 rs6746294 chr2:233583050 C/G cg08000102 chr2:233561755 GIGYF2 -0.72 -10.26 -0.49 1.01e-21 Coronary artery disease; LIHC cis rs589448 0.967 rs634512 chr12:69754012 C/T cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 1.02e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs9768139 0.708 rs10234067 chr7:158114542 C/T cg25566285 chr7:158114605 PTPRN2 0.22 6.02 0.31 4.4e-9 Calcium levels; LIHC cis rs9556958 0.708 rs9513435 chr13:99160334 C/G cg07423050 chr13:99094983 FARP1 -0.33 -5.85 -0.3 1.13e-8 Educational attainment (years of education); LIHC cis rs7772486 0.719 rs702317 chr6:146005010 C/T cg05347473 chr6:146136440 FBXO30 -0.37 -5.93 -0.31 7.27e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs35110281 0.715 rs969060 chr21:45080852 T/G cg21573476 chr21:45109991 RRP1B -0.6 -11.29 -0.52 2.54e-25 Mean corpuscular volume; LIHC cis rs6952808 0.792 rs12536261 chr7:1953571 G/A cg20295408 chr7:1910781 MAD1L1 -0.5 -7.27 -0.37 2.39e-12 Bipolar disorder and schizophrenia; LIHC cis rs7044106 0.734 rs12553070 chr9:123485266 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.58 8.84 0.43 5.3e-17 Hip circumference adjusted for BMI; LIHC cis rs2980439 0.870 rs2945230 chr8:8109936 A/G cg14343924 chr8:8086146 FLJ10661 0.47 5.92 0.31 7.66e-9 Neuroticism; LIHC cis rs694739 0.894 rs12421615 chr11:64021605 G/A cg02228329 chr11:64053129 BAD;GPR137 0.73 9.12 0.44 6.47e-18 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs858239 0.600 rs4409314 chr7:23127952 T/C cg23682824 chr7:23144976 KLHL7 0.45 6.62 0.34 1.41e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs10791097 0.694 rs7106995 chr11:130758152 G/T cg22079354 chr11:130786696 SNX19 0.43 6.11 0.31 2.76e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg05665937 chr4:1216051 CTBP1 -0.45 -5.98 -0.31 5.62e-9 Obesity-related traits; LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg06873352 chr17:61820015 STRADA -0.59 -9.61 -0.46 1.64e-19 Prudent dietary pattern; LIHC cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg13271783 chr10:134563150 INPP5A -0.57 -7.2 -0.36 3.87e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7607369 0.637 rs17462630 chr2:219286541 C/G cg02176678 chr2:219576539 TTLL4 -0.5 -6.87 -0.35 3.09e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg08888203 chr3:10149979 C3orf24 0.53 6.43 0.33 4.35e-10 Alzheimer's disease; LIHC cis rs4755351 0.527 rs12420035 chr11:33111487 A/G cg05567920 chr11:33183001 CSTF3 0.42 6.07 0.31 3.44e-9 Lung cancer in ever smokers; LIHC cis rs9420 0.809 rs11600169 chr11:57464945 T/A cg19752551 chr11:57585705 CTNND1 -0.51 -7.14 -0.36 5.64e-12 Schizophrenia; LIHC cis rs3784262 0.935 rs4646636 chr15:58251034 A/G cg12031962 chr15:58353849 ALDH1A2 -0.31 -6.23 -0.32 1.33e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs11971779 0.752 rs4732371 chr7:139077317 T/A cg07862535 chr7:139043722 LUC7L2 0.63 10.8 0.5 1.37e-23 Diisocyanate-induced asthma; LIHC cis rs7044106 0.762 rs1547268 chr9:123408688 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.25 0.52 3.29e-25 Hip circumference adjusted for BMI; LIHC cis rs7267979 0.932 rs417110 chr20:25458297 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.45 6.77 0.34 5.56e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs61677309 1.000 rs3782040 chr11:118176097 A/G cg06090739 chr11:118230722 UBE4A 0.34 6.16 0.32 2e-9 Lung cancer in ever smokers; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg09984469 chr2:72372162 CYP26B1 -0.51 -6.11 -0.31 2.76e-9 Systolic blood pressure; LIHC cis rs7617773 0.780 rs35778847 chr3:48346985 G/T cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC trans rs7668874 0.738 rs7683194 chr4:116813821 T/C cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg04267008 chr7:1944627 MAD1L1 -0.69 -11.1 -0.51 1.19e-24 Bipolar disorder and schizophrenia; LIHC cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg23758822 chr17:41437982 NA 0.95 17.59 0.69 8.51e-50 Menopause (age at onset); LIHC cis rs7408868 1.000 rs10407320 chr19:15275716 G/C cg14696996 chr19:15285081 NOTCH3 0.53 7.11 0.36 6.93e-12 Pulse pressure; LIHC cis rs10791097 0.677 rs11222359 chr11:130730648 A/G cg12179176 chr11:130786555 SNX19 0.73 11.5 0.53 4.27e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2050392 0.861 rs303448 chr10:30727084 G/T cg25182066 chr10:30743637 MAP3K8 -0.49 -7.98 -0.4 2.19e-14 Inflammatory bowel disease; LIHC cis rs8114671 0.562 rs7266550 chr20:33495510 C/T cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.04e-19 Height; LIHC cis rs7927771 0.965 rs1064608 chr11:47640429 G/C cg20135002 chr11:47629003 NA -0.58 -10.06 -0.48 4.98e-21 Subjective well-being; LIHC cis rs8062405 0.755 rs4788078 chr16:28559981 G/A cg00204512 chr16:28754710 NA 0.41 7.16 0.36 4.9e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg06481639 chr22:41940642 POLR3H -0.7 -6.98 -0.35 1.5e-11 Vitiligo; LIHC cis rs9916302 0.904 rs57399933 chr17:37551189 A/G cg00129232 chr17:37814104 STARD3 0.4 6.43 0.33 4.4e-10 Glomerular filtration rate (creatinine); LIHC cis rs295140 0.526 rs295114 chr2:201195602 C/T cg23649088 chr2:200775458 C2orf69 0.42 5.87 0.3 1.01e-8 QT interval; LIHC cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg04944784 chr2:26401820 FAM59B 0.72 9.15 0.44 5.12e-18 Gut microbiome composition (summer); LIHC trans rs208520 0.661 rs1776361 chr6:66822270 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.4 -0.41 1.24e-15 Exhaled nitric oxide output; LIHC cis rs9790314 0.747 rs1599378 chr3:160874511 A/C cg03342759 chr3:160939853 NMD3 -0.76 -10.54 -0.5 1.1e-22 Morning vs. evening chronotype; LIHC cis rs2153535 0.601 rs4140584 chr6:8540614 C/G cg23788917 chr6:8435910 SLC35B3 -0.61 -8.57 -0.42 3.71e-16 Motion sickness; LIHC cis rs7617773 0.780 rs4511916 chr3:48350366 G/A cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs9640161 0.789 rs6964110 chr7:150041836 A/C cg10018233 chr7:150070692 REPIN1 0.53 8.95 0.44 2.23e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs5769765 0.862 rs9616381 chr22:50312382 G/A cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC trans rs875971 0.545 rs7811204 chr7:65852200 G/A cg26939375 chr7:64535504 NA 0.4 6.29 0.32 9.67e-10 Aortic root size; LIHC cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg10411590 chr13:21900810 NA 0.41 6.93 0.35 2.05e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs11077998 0.840 rs9910991 chr17:80481193 G/A cg10255544 chr17:80519551 FOXK2 0.49 8.7 0.43 1.42e-16 Reticulocyte fraction of red cells; LIHC cis rs7651039 0.846 rs2174267 chr3:15645835 T/C cg16303742 chr3:15540471 COLQ 0.52 8.93 0.43 2.74e-17 Coronary heart disease; LIHC cis rs12701220 0.689 rs12533004 chr7:1095410 C/T cg02733842 chr7:1102375 C7orf50 -0.69 -7.49 -0.38 5.79e-13 Bronchopulmonary dysplasia; LIHC cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.42 0.33 4.62e-10 Mean platelet volume; LIHC cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 8.49 0.42 6.51e-16 Platelet count; LIHC cis rs853679 0.882 rs9468287 chr6:28079741 G/T cg16479474 chr6:28041457 NA 0.5 5.88 0.3 9.81e-9 Depression; LIHC cis rs765787 0.530 rs2413776 chr15:45544170 A/G cg24006582 chr15:45444508 DUOX1 -0.48 -6.83 -0.35 3.85e-11 Uric acid levels; LIHC trans rs6560039 1 rs6560039 chr9:90474946 C/T cg24436365 chr6:63940138 NA 0.4 8.76 0.43 9.09e-17 Gait variability; LIHC cis rs12497850 0.864 rs4955410 chr3:49181218 A/G cg07636037 chr3:49044803 WDR6 0.86 14.97 0.63 2.6e-39 Parkinson's disease; LIHC cis rs2836974 0.545 rs2776311 chr21:40716885 A/G cg11890956 chr21:40555474 PSMG1 0.55 8.04 0.4 1.53e-14 Cognitive function; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.32 0.41 2.06e-15 Height; LIHC cis rs1008375 0.897 rs4334752 chr4:17615430 C/T cg16339924 chr4:17578868 LAP3 0.44 6.0 0.31 5.14e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs74233809 1.000 rs11191560 chr10:104869038 A/G cg03493300 chr10:104813866 CNNM2 0.45 5.99 0.31 5.3e-9 Birth weight; LIHC cis rs9611565 0.607 rs132792 chr22:42062822 C/T cg06634786 chr22:41940651 POLR3H 0.55 6.05 0.31 3.87e-9 Vitiligo; LIHC cis rs11098499 0.863 rs2291185 chr4:120434833 C/A cg09307838 chr4:120376055 NA 0.77 11.93 0.54 1.14e-27 Corneal astigmatism; LIHC cis rs6747952 0.866 rs6726348 chr2:239084119 C/T cg17459225 chr2:239074497 NA 0.37 5.9 0.3 8.9e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7412746 0.622 rs72704654 chr1:150826410 G/A cg18016565 chr1:150552671 MCL1 0.56 10.28 0.49 9.16e-22 Melanoma; LIHC cis rs7909074 0.798 rs914699 chr10:45377066 A/C cg04218760 chr10:45406644 TMEM72 -0.25 -7.65 -0.38 2.03e-13 Mean corpuscular volume; LIHC trans rs7937682 0.924 rs564601 chr11:111594077 T/C cg18187862 chr3:45730750 SACM1L 0.57 6.65 0.34 1.17e-10 Primary sclerosing cholangitis; LIHC cis rs12477438 0.798 rs896886 chr2:99652713 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.12 16.01 0.65 1.96e-43 Chronic sinus infection; LIHC cis rs11583043 0.872 rs1326380 chr1:101293753 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.52 6.43 0.33 4.18e-10 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7044106 0.791 rs10985001 chr9:123484232 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.04 0.51 1.88e-24 Hip circumference adjusted for BMI; LIHC trans rs1814175 0.546 rs1614397 chr11:49913384 G/C cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg05025164 chr4:1340916 KIAA1530 -0.76 -11.63 -0.53 1.41e-26 Longevity; LIHC cis rs8084351 0.599 rs4940245 chr18:50694137 A/G cg24270629 chr18:50823537 DCC -0.47 -6.96 -0.35 1.72e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9309473 0.950 rs6546858 chr2:73838613 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.93 -0.35 2.07e-11 Metabolite levels; LIHC cis rs1552244 0.572 rs3894323 chr3:10168967 G/A cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs35110281 0.574 rs1836856 chr21:44964638 A/T cg01579765 chr21:45077557 HSF2BP -0.31 -5.88 -0.3 9.54e-9 Mean corpuscular volume; LIHC cis rs4803468 1.000 rs11880539 chr19:41918949 A/C cg09537434 chr19:41945824 ATP5SL 1.02 21.83 0.76 8.48e-67 Height; LIHC cis rs12744310 1.000 rs34008156 chr1:41773182 G/T cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg00656387 chr3:40428638 ENTPD3 0.48 7.88 0.39 4.4e-14 Renal cell carcinoma; LIHC cis rs2404602 0.716 rs4886813 chr15:76838221 C/T cg03037974 chr15:76606532 NA -0.73 -14.24 -0.61 1.89e-36 Blood metabolite levels; LIHC cis rs9911578 1.000 rs302840 chr17:56673079 C/G cg12560992 chr17:57184187 TRIM37 0.97 17.78 0.69 1.45e-50 Intelligence (multi-trait analysis); LIHC cis rs4700695 0.719 rs27087 chr5:65453050 G/A cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.46e-15 Facial morphology (factor 19); LIHC trans rs877282 0.853 rs11593836 chr10:756715 G/A cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg10702113 chr3:196664466 NCBP2 0.36 6.08 0.31 3.14e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg12310025 chr6:25882481 NA 0.68 8.76 0.43 9.26e-17 Intelligence (multi-trait analysis); LIHC cis rs240764 0.645 rs240152 chr6:101067489 G/C cg09795085 chr6:101329169 ASCC3 0.44 6.38 0.33 5.77e-10 Neuroticism; LIHC cis rs7089973 0.604 rs10885620 chr10:116630048 A/T cg23260525 chr10:116636907 FAM160B1 0.4 7.8 0.39 7.48e-14 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2455601 0.786 rs3763914 chr11:8940703 G/T cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -6.13 -0.31 2.49e-9 Schizophrenia; LIHC cis rs7927592 0.763 rs10896326 chr11:68234571 T/C cg01657329 chr11:68192670 LRP5 -0.48 -7.02 -0.35 1.23e-11 Total body bone mineral density; LIHC cis rs10791323 0.592 rs2851115 chr11:133705381 C/A cg06766960 chr11:133703094 NA -0.66 -10.93 -0.51 4.66e-24 Childhood ear infection; LIHC cis rs1075232 1.000 rs72722829 chr15:31639114 G/A cg01030201 chr15:31746330 NA -0.78 -6.0 -0.31 5.07e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs7845219 0.525 rs10956931 chr8:95930301 A/G cg16049864 chr8:95962084 TP53INP1 -0.42 -6.51 -0.33 2.69e-10 Type 2 diabetes; LIHC cis rs6762 0.748 rs3059 chr11:840319 C/T cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.63 -0.46 1.42e-19 Mean platelet volume; LIHC cis rs3857067 0.806 rs6817795 chr4:95127716 T/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.61 -0.38 2.61e-13 QT interval; LIHC cis rs4824093 0.610 rs74371371 chr22:50314074 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -5.71 -0.3 2.4e-8 Amyotrophic lateral sclerosis (sporadic); LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg03244087 chr7:25164935 CYCS -0.38 -6.07 -0.31 3.48e-9 Eotaxin levels; LIHC cis rs763121 0.853 rs5750673 chr22:39110124 G/A cg14440974 chr22:39074834 NA -0.45 -7.17 -0.36 4.73e-12 Menopause (age at onset); LIHC cis rs11690935 0.851 rs7573003 chr2:172741415 T/A cg13550731 chr2:172543902 DYNC1I2 -0.81 -14.53 -0.62 1.41e-37 Schizophrenia; LIHC cis rs7493 0.755 rs13223537 chr7:94966167 C/T cg17330251 chr7:94953956 PON1 0.48 5.92 0.3 7.95e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs7903847 0.667 rs10882931 chr10:99165794 C/A cg08345082 chr10:99160200 RRP12 -0.4 -6.91 -0.35 2.39e-11 Granulocyte percentage of myeloid white cells; LIHC trans rs61332075 0.501 rs55706928 chr2:239445806 T/C cg01134436 chr17:81009848 B3GNTL1 0.75 6.32 0.32 8.37e-10 Lung function (FEV1/FVC); LIHC cis rs941408 0.515 rs7253128 chr19:2776982 C/T cg02580895 chr19:2754563 NA -0.47 -6.91 -0.35 2.35e-11 Total cholesterol levels; LIHC cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg08888203 chr3:10149979 C3orf24 0.53 6.46 0.33 3.67e-10 Alzheimer's disease; LIHC cis rs9291683 0.538 rs11727199 chr4:10036190 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.41 0.37 9.86e-13 Bone mineral density; LIHC cis rs1395 0.744 rs11126936 chr2:27483101 A/C cg23587288 chr2:27483067 SLC30A3 0.37 7.04 0.36 1.09e-11 Blood metabolite levels; LIHC cis rs3762637 1.000 rs7617042 chr3:122190985 C/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs17253792 0.822 rs80321745 chr14:56162947 T/A cg01858014 chr14:56050164 KTN1 -0.71 -7.27 -0.37 2.4e-12 Putamen volume; LIHC cis rs34172651 0.917 rs12923476 chr16:24798079 G/A cg00339695 chr16:24857497 SLC5A11 0.55 8.43 0.41 9.93e-16 Intelligence (multi-trait analysis); LIHC cis rs8180040 1.000 rs807810 chr3:47403892 G/A cg16586182 chr3:47516702 SCAP 0.55 10.06 0.48 5.16e-21 Colorectal cancer; LIHC cis rs16828019 0.852 rs10489520 chr1:41511755 C/A cg03962019 chr1:41807865 NA 0.49 7.03 0.36 1.13e-11 Intelligence (multi-trait analysis); LIHC cis rs244293 0.730 rs12945579 chr17:53022714 A/T cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.03 -0.31 4.32e-9 Menarche (age at onset); LIHC cis rs2732480 0.500 rs2450986 chr12:48661688 G/A cg21466736 chr12:48725269 NA -0.71 -10.97 -0.51 3.49e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg14222432 chr12:29376421 FAR2 0.38 7.2 0.36 3.97e-12 QT interval; LIHC cis rs208520 0.690 rs2208442 chr6:66867004 T/C cg07460842 chr6:66804631 NA -0.78 -8.54 -0.42 4.49e-16 Exhaled nitric oxide output; LIHC cis rs3008870 1.000 rs2815361 chr1:67494591 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.15 0.66 5.24e-44 Lymphocyte percentage of white cells; LIHC cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg16325326 chr1:53192061 ZYG11B -0.49 -8.64 -0.42 2.22e-16 Monocyte count; LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg00656387 chr3:40428638 ENTPD3 0.51 8.38 0.41 1.36e-15 Renal cell carcinoma; LIHC cis rs12079745 0.623 rs2275300 chr1:169337515 G/T cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 2.01e-11 QT interval; LIHC cis rs7572733 0.534 rs700680 chr2:198707950 A/T cg10820045 chr2:198174542 NA -0.49 -7.61 -0.38 2.64e-13 Dermatomyositis; LIHC trans rs637571 0.528 rs566266 chr11:65573587 A/C cg17712092 chr4:129076599 LARP1B -0.7 -10.23 -0.48 1.32e-21 Eosinophil percentage of white cells; LIHC cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg03452623 chr4:187889614 NA 0.32 8.2 0.41 4.87e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs477692 0.967 rs519690 chr10:131424033 G/A cg05714579 chr10:131428358 MGMT 0.45 7.4 0.37 1.09e-12 Response to temozolomide; LIHC cis rs2842992 0.724 rs4709368 chr6:160204127 C/T cg11366901 chr6:160182831 ACAT2 -0.84 -14.67 -0.62 3.85e-38 Age-related macular degeneration (geographic atrophy); LIHC cis rs921968 0.541 rs10205073 chr2:219412784 C/A cg02985541 chr2:219472218 PLCD4 -0.42 -6.83 -0.35 3.99e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs2262909 0.962 rs422344 chr19:22230956 C/G cg17074339 chr11:11642133 GALNTL4 0.4 6.1 0.31 2.92e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg00091569 chr3:40428383 ENTPD3 -0.37 -6.28 -0.32 1.01e-9 Renal cell carcinoma; LIHC cis rs6831352 0.879 rs56295995 chr4:100060899 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs7412746 0.658 rs2272214 chr1:150931462 C/T cg15448220 chr1:150897856 SETDB1 0.42 6.72 0.34 7.61e-11 Melanoma; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg18306943 chr3:40428807 ENTPD3 0.42 7.46 0.37 7.18e-13 Renal cell carcinoma; LIHC cis rs2153535 0.580 rs1889715 chr6:8443475 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.81e-14 Motion sickness; LIHC cis rs7927592 0.956 rs60212556 chr11:68305494 C/T cg01657329 chr11:68192670 LRP5 -0.47 -6.11 -0.31 2.78e-9 Total body bone mineral density; LIHC trans rs10078397 0.518 rs6594295 chr5:107601618 C/G cg14380426 chr14:74418789 COQ6 -0.49 -6.07 -0.31 3.4e-9 Neuroticism; LIHC cis rs8078723 0.630 rs60137005 chr17:38129996 A/T cg17344932 chr17:38183730 MED24;SNORD124 -0.59 -9.98 -0.48 9.15e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg13395646 chr4:1353034 KIAA1530 -0.44 -6.39 -0.33 5.52e-10 Longevity; LIHC cis rs4727027 0.866 rs1358062 chr7:148783743 T/C cg23583168 chr7:148888333 NA -0.67 -9.34 -0.45 1.23e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7095607 0.560 rs7095238 chr10:69913203 T/C cg18986048 chr10:69913749 MYPN 0.41 6.07 0.31 3.47e-9 Lung function (FVC); LIHC cis rs10979 1.000 rs6570566 chr6:143899534 G/A cg25407410 chr6:143891975 LOC285740 -0.35 -5.74 -0.3 2.13e-8 Hypospadias; LIHC trans rs526821 0.553 rs519637 chr11:55295935 A/T cg15704280 chr7:45808275 SEPT13 -0.52 -7.98 -0.4 2.29e-14 Pediatric bone mineral density (spine); LIHC cis rs4721295 0.573 rs3779000 chr7:2181628 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.8 -0.47 3.82e-20 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs10791323 0.536 rs1944731 chr11:133726067 G/A cg06766960 chr11:133703094 NA -0.66 -11.14 -0.52 8.18e-25 Childhood ear infection; LIHC cis rs7408868 1.000 rs1548554 chr19:15277938 C/T cg14696996 chr19:15285081 NOTCH3 0.53 7.02 0.36 1.17e-11 Pulse pressure; LIHC cis rs4919087 0.532 rs56189004 chr10:99086632 A/G cg25902810 chr10:99078978 FRAT1 -0.62 -7.82 -0.39 6.8e-14 Monocyte count; LIHC cis rs600806 0.854 rs3768496 chr1:109866569 T/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.25 -0.36 2.8e-12 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg10755058 chr3:40428713 ENTPD3 0.39 6.68 0.34 9.56e-11 Renal cell carcinoma; LIHC cis rs28374715 0.662 rs1554445 chr15:41503198 A/C cg18705301 chr15:41695430 NDUFAF1 -0.93 -10.26 -0.49 1.01e-21 Ulcerative colitis; LIHC cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg05590025 chr7:65112418 INTS4L2 -0.63 -6.81 -0.35 4.46e-11 Diabetic kidney disease; LIHC cis rs9303280 0.870 rs6503524 chr17:38069809 C/T cg11212589 chr17:38028394 ZPBP2 -0.34 -6.88 -0.35 2.79e-11 Self-reported allergy; LIHC cis rs970821 0.667 rs2385508 chr8:124744682 C/A cg00283535 chr8:124749564 ANXA13 0.42 7.7 0.38 1.46e-13 Breast cancer; LIHC cis rs7737355 0.947 rs32115 chr5:131051328 A/G cg06307176 chr5:131281290 NA 0.4 5.8 0.3 1.54e-8 Life satisfaction; LIHC cis rs17401966 1.000 rs12132635 chr1:10430479 G/A cg15208524 chr1:10270712 KIF1B 0.44 6.14 0.32 2.27e-9 Hepatocellular carcinoma; LIHC cis rs7647973 0.626 rs4855882 chr3:49715354 G/T cg03060546 chr3:49711283 APEH 0.54 5.88 0.3 9.97e-9 Menarche (age at onset); LIHC cis rs7512552 0.839 rs1260367 chr1:150344514 C/T cg15654264 chr1:150340011 RPRD2 0.68 11.18 0.52 6.33e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs6809651 0.524 rs56940353 chr3:185798296 T/C cg00760338 chr3:185826511 ETV5 -0.85 -12.73 -0.57 1.18e-30 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg02290350 chr8:58132656 NA 0.5 9.94 0.47 1.23e-20 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs72627123 0.867 rs59675549 chr14:74469480 A/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 8.71 0.43 1.33e-16 Morning vs. evening chronotype; LIHC cis rs3741404 0.620 rs2236647 chr11:63964605 A/G cg18225595 chr11:63971243 STIP1 -0.6 -9.53 -0.46 2.92e-19 Platelet count; LIHC cis rs6748734 0.894 rs4675869 chr2:241827696 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -8.11 -0.4 9.08e-15 Urinary metabolites; LIHC cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.82 8.23 0.41 4.08e-15 Platelet count; LIHC cis rs9888615 1.000 rs12881375 chr14:53371980 C/A cg00686598 chr14:53173677 PSMC6 -0.51 -6.43 -0.33 4.26e-10 Systolic blood pressure; LIHC cis rs9296092 0.500 rs9461885 chr6:33521069 G/T cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7918232 1.000 rs7918232 chr10:27369162 A/G cg14240646 chr10:27532245 ACBD5 -0.62 -6.0 -0.31 4.96e-9 Breast cancer; LIHC trans rs4906332 1.000 rs4900574 chr14:103879024 G/A cg17675199 chr6:35436792 RPL10A -0.31 -6.22 -0.32 1.46e-9 Coronary artery disease; LIHC cis rs9596863 1.000 rs9568939 chr13:54411497 A/C ch.13.53330881F chr13:54432880 NA 0.44 5.98 0.31 5.48e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs2359714 0.905 rs7515420 chr1:118823147 A/G cg10221014 chr12:47618577 FAM113B -0.37 -6.04 -0.31 3.99e-9 Breast size; LIHC cis rs7586673 0.893 rs889925 chr2:161971597 T/C cg21518248 chr2:162101506 NA 0.42 6.21 0.32 1.56e-9 Intelligence (multi-trait analysis); LIHC cis rs12079745 0.793 rs12058325 chr1:169264037 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.78 -6.94 -0.35 2.01e-11 QT interval; LIHC trans rs1005277 0.528 rs2057228 chr10:38515766 T/C cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16990120 chr1:149871080 BOLA1 0.39 6.04 0.31 4.04e-9 Pancreatic cancer; LIHC cis rs10845606 0.505 rs7299416 chr12:12831568 C/T cg09462578 chr12:12878428 APOLD1 0.42 6.53 0.33 2.45e-10 Systemic lupus erythematosus; LIHC cis rs11098499 0.863 rs1480939 chr4:120456927 T/C cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg02475777 chr4:1388615 CRIPAK 0.54 8.11 0.4 9.19e-15 Longevity; LIHC cis rs2303745 0.589 rs11882562 chr19:17395055 C/G cg04248312 chr19:17393744 ANKLE1 0.73 12.29 0.55 5.15e-29 Systemic lupus erythematosus; LIHC cis rs9814567 0.752 rs4456908 chr3:134340353 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.56 -8.91 -0.43 3.07e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9527 0.830 rs11191442 chr10:104643596 T/A cg15744005 chr10:104629667 AS3MT -0.34 -6.73 -0.34 7.2e-11 Arsenic metabolism; LIHC cis rs9420 0.961 rs682503 chr11:57640994 C/G cg19752551 chr11:57585705 CTNND1 0.46 6.38 0.33 5.8e-10 Schizophrenia; LIHC cis rs6540556 0.682 rs667681 chr1:209914449 A/G cg05527609 chr1:210001259 C1orf107 0.58 7.77 0.39 9.22e-14 Red blood cell count; LIHC cis rs3749237 1.000 rs11920900 chr3:49823024 G/C cg03060546 chr3:49711283 APEH 0.39 6.04 0.31 3.95e-9 Resting heart rate; LIHC cis rs6701037 0.681 rs1894709 chr1:175132371 G/T cg00958927 chr1:175162553 KIAA0040 -0.38 -6.21 -0.32 1.52e-9 Alcohol dependence; LIHC cis rs1559088 0.901 rs12610053 chr19:33582606 A/G cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03573702 chr19:44669354 ZNF226 0.46 6.93 0.35 2.05e-11 Pancreatic cancer; LIHC cis rs2637266 0.756 rs2583064 chr10:78557708 A/G cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.96e-9 Pulmonary function; LIHC cis rs507080 0.961 rs4457789 chr11:118539170 G/T cg04173919 chr11:118528438 PHLDB1 0.33 6.2 0.32 1.64e-9 Serum metabolite levels; LIHC cis rs2070488 0.965 rs7640050 chr3:38525864 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.95 0.65 3.45e-43 Electrocardiographic conduction measures; LIHC cis rs9640161 0.636 rs3735171 chr7:150033882 A/G cg17279839 chr7:150038598 RARRES2 0.6 12.21 0.55 1.01e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg04546413 chr19:29218101 NA 0.57 9.95 0.47 1.17e-20 Methadone dose in opioid dependence; LIHC cis rs9513627 0.915 rs73556177 chr13:100121840 G/A cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs6952808 0.572 rs1860826 chr7:2112506 G/A cg22963979 chr7:1858916 MAD1L1 -0.38 -6.0 -0.31 4.89e-9 Bipolar disorder and schizophrenia; LIHC cis rs533581 0.873 rs555191 chr16:88978850 C/T cg03970086 chr16:88974840 CBFA2T3 0.31 5.96 0.31 6.26e-9 Social autistic-like traits; LIHC trans rs4906332 0.901 rs4900575 chr14:103899169 G/C cg17675199 chr6:35436792 RPL10A 0.32 6.41 0.33 4.87e-10 Coronary artery disease; LIHC cis rs4819052 0.807 rs28715237 chr21:46673768 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.88 0.39 4.55e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9517320 0.515 rs9556972 chr13:99209815 C/T cg07423050 chr13:99094983 FARP1 -0.49 -8.61 -0.42 2.72e-16 Longevity; LIHC cis rs295140 0.546 rs295119 chr2:201117944 C/T cg23649088 chr2:200775458 C2orf69 0.44 5.95 0.31 6.53e-9 QT interval; LIHC cis rs6463523 0.933 rs6974151 chr7:758269 T/C cg11064039 chr7:766100 PRKAR1B;HEATR2 1.01 17.79 0.69 1.34e-50 Subjective well-being; LIHC cis rs6442522 0.560 rs3816526 chr3:15516910 T/C cg16303742 chr3:15540471 COLQ 0.36 5.91 0.3 8.12e-9 Uric acid levels; LIHC cis rs8078723 0.966 rs57968500 chr17:38145828 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.27 -0.45 2.13e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs72653721 1.000 rs72653721 chr6:10971886 C/T cg13562911 chr6:11044106 ELOVL2 0.5 7.02 0.35 1.2e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs72781680 0.898 rs56179550 chr2:23934867 C/T cg08917208 chr2:24149416 ATAD2B 0.97 8.25 0.41 3.56e-15 Lymphocyte counts; LIHC cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg11494091 chr17:61959527 GH2 -0.52 -9.99 -0.48 8.87e-21 Prudent dietary pattern; LIHC cis rs11690935 0.959 rs6745143 chr2:172650382 G/A cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.54 -0.69 1.36e-49 Schizophrenia; LIHC cis rs5769765 0.908 rs9616388 chr22:50313438 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs11761441 0.669 rs13241486 chr7:79536 G/C cg19711949 chr7:80907 NA 0.33 6.68 0.34 9.99e-11 Alzheimer's disease in APOE e4- carriers; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17290526 chr17:61600384 KCNH6 -0.42 -6.08 -0.31 3.14e-9 Alopecia areata; LIHC cis rs6461049 0.519 rs3778992 chr7:2175313 C/G cg04267008 chr7:1944627 MAD1L1 -0.53 -8.2 -0.41 4.92e-15 Schizophrenia; LIHC trans rs875971 0.660 rs6460308 chr7:66084740 T/C cg26939375 chr7:64535504 NA -0.43 -6.97 -0.35 1.65e-11 Aortic root size; LIHC cis rs422249 0.512 rs1535 chr11:61597972 A/G cg27386326 chr11:61587980 NA 0.72 15.56 0.64 1.18e-41 Trans fatty acid levels; LIHC cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg02290350 chr8:58132656 NA 0.42 8.81 0.43 6.51e-17 Developmental language disorder (linguistic errors); LIHC cis rs6684514 1.000 rs10908500 chr1:156280671 A/T cg16558208 chr1:156270281 VHLL 0.54 10.17 0.48 2.17e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs10540 1.000 rs12788729 chr11:502371 G/A cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.15e-11 Body mass index; LIHC cis rs9399135 0.967 rs45544135 chr6:135324051 T/C cg22676075 chr6:135203613 NA 0.38 6.29 0.32 9.78e-10 Red blood cell count; LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs4638749 0.677 rs4396668 chr2:108840364 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -5.96 -0.31 6.23e-9 Blood pressure; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17470061 chr1:33336618 FNDC5 -0.41 -6.05 -0.31 3.79e-9 Calcium levels; LIHC cis rs1401999 0.510 rs12634398 chr3:183708405 A/G cg01324343 chr3:183735012 ABCC5 0.39 6.3 0.32 9.09e-10 Anterior chamber depth; LIHC cis rs17125944 0.505 rs2295826 chr14:53174923 C/T cg00686598 chr14:53173677 PSMC6 -1.19 -15.09 -0.63 8.25e-40 Alzheimer's disease (late onset); LIHC cis rs986417 1.000 rs4243618 chr14:61067022 T/C cg27398547 chr14:60952738 C14orf39 0.66 6.55 0.33 2.15e-10 Gut microbiota (bacterial taxa); LIHC cis rs9790314 0.718 rs1599383 chr3:160829820 T/C cg03342759 chr3:160939853 NMD3 -0.72 -9.82 -0.47 3.18e-20 Morning vs. evening chronotype; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg06420487 chr17:61919686 SMARCD2 0.45 6.22 0.32 1.43e-9 Height; LIHC cis rs9457247 0.765 rs1322077 chr6:167424293 T/C cg23791538 chr6:167370224 RNASET2 -0.51 -7.76 -0.39 9.79e-14 Crohn's disease; LIHC cis rs17685 0.753 rs869804 chr7:75688954 A/G cg01364799 chr7:75623366 TMEM120A -0.52 -7.88 -0.39 4.34e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs240764 0.555 rs4840150 chr6:101183774 T/C cg09795085 chr6:101329169 ASCC3 0.42 6.18 0.32 1.8e-9 Neuroticism; LIHC cis rs7617773 0.563 rs13082269 chr3:48392274 G/A cg11946769 chr3:48343235 NME6 0.55 6.78 0.34 5.21e-11 Coronary artery disease; LIHC cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg17971929 chr21:40555470 PSMG1 -0.41 -6.18 -0.32 1.79e-9 Menarche (age at onset); LIHC cis rs4979906 1.000 rs4325263 chr10:79444236 A/G cg07817648 chr10:79422355 NA -0.3 -6.29 -0.32 9.56e-10 Mortality in heart failure; LIHC trans rs7219021 1.000 rs72831853 chr17:46842575 A/T cg14968300 chr8:23585186 NA -0.35 -6.44 -0.33 4.1e-10 Schizophrenia or bipolar disorder; LIHC cis rs3796352 1.000 rs11718538 chr3:52975987 C/G cg07884673 chr3:53033167 SFMBT1 0.88 6.5 0.33 2.77e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2072499 0.778 rs2842868 chr1:156196407 A/C cg25208724 chr1:156163844 SLC25A44 0.62 7.37 0.37 1.31e-12 Testicular germ cell tumor; LIHC cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg11301795 chr4:187892539 NA -0.27 -7.1 -0.36 7.05e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs881375 0.715 rs11794516 chr9:123640230 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.79 0.34 5e-11 Rheumatoid arthritis; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg13395646 chr4:1353034 KIAA1530 -0.44 -6.16 -0.32 2.09e-9 Longevity; LIHC cis rs2766692 0.956 rs35696661 chr14:100742355 G/C cg14866419 chr14:100704911 YY1 0.44 5.95 0.31 6.67e-9 Electroencephalographic traits in alcoholism; LIHC cis rs2112347 0.502 rs34342 chr5:74934213 A/C cg19683494 chr5:74908142 NA -0.8 -10.39 -0.49 3.82e-22 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs17818399 0.749 rs35625984 chr2:46805908 A/G cg02822958 chr2:46747628 ATP6V1E2 0.48 7.18 0.36 4.38e-12 Height; LIHC cis rs9914988 0.943 rs9893782 chr17:27108132 C/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs911119 0.954 rs2405367 chr20:23622880 A/G cg16589663 chr20:23618590 CST3 -0.73 -7.49 -0.38 5.76e-13 Chronic kidney disease; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs10791097 0.694 rs11222369 chr11:130744670 A/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2066819 1.000 rs79718165 chr12:56644251 C/T cg26714650 chr12:56694279 CS -1.33 -12.81 -0.57 5.98e-31 Psoriasis vulgaris; LIHC trans rs1005277 0.579 rs2474608 chr10:38457109 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg04709771 chr16:646395 RAB40C 0.45 8.37 0.41 1.44e-15 Height; LIHC cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.11 0.51 1.12e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs35306767 0.714 rs12767171 chr10:1084491 A/G cg26597838 chr10:835615 NA 0.58 6.46 0.33 3.59e-10 Eosinophil percentage of granulocytes; LIHC cis rs10779751 0.734 rs2261217 chr1:11127764 C/A cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs1506636 0.962 rs2896335 chr7:123376855 A/T cg03229431 chr7:123269106 ASB15 -0.62 -12.58 -0.56 4.45e-30 Plateletcrit;Platelet count; LIHC cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg12310025 chr6:25882481 NA -0.43 -6.55 -0.33 2.12e-10 Height; LIHC cis rs10861342 1.000 rs11112396 chr12:105568359 T/G cg23923672 chr12:105501055 KIAA1033 0.69 8.59 0.42 3.19e-16 IgG glycosylation; LIHC trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg11235426 chr6:292522 DUSP22 -0.56 -7.83 -0.39 6.1e-14 Menopause (age at onset); LIHC cis rs1499280 1.000 rs7711599 chr5:52098755 A/G cg21153758 chr5:52083992 ITGA1;PELO -0.65 -5.95 -0.31 6.74e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC trans rs2096176 0.530 rs7911700 chr10:26286367 G/A cg01396774 chr2:218299024 DIRC3 -0.31 -6.12 -0.31 2.55e-9 Obesity-related traits; LIHC cis rs7666738 0.716 rs7656233 chr4:99079237 G/A cg05340658 chr4:99064831 C4orf37 0.7 12.44 0.56 1.42e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs1580019 0.961 rs6949851 chr7:32493807 T/G cg06627557 chr7:32535165 LSM5;AVL9 0.78 11.74 0.54 5.73e-27 Cognitive ability; LIHC trans rs72960926 0.744 rs72954354 chr6:74949552 C/G cg07247405 chr1:2484626 LOC115110 0.53 6.41 0.33 4.83e-10 Metabolite levels (MHPG); LIHC cis rs7251806 1 rs7251806 chr19:16499569 C/T cg10248733 chr19:16607483 C19orf44;CALR3 0.66 7.81 0.39 6.9e-14 Lymphocyte counts; LIHC cis rs16854884 0.586 rs7611326 chr3:143736374 C/T cg06585982 chr3:143692056 C3orf58 0.57 7.41 0.37 1.01e-12 Economic and political preferences (feminism/equality); LIHC cis rs11958404 0.615 rs10044900 chr5:157451580 C/T cg05962755 chr5:157440814 NA -0.58 -7.81 -0.39 7.01e-14 IgG glycosylation; LIHC cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg05590025 chr7:65112418 INTS4L2 -0.71 -7.37 -0.37 1.33e-12 Diabetic kidney disease; LIHC cis rs473651 0.904 rs62196716 chr2:239356977 C/G cg18131467 chr2:239335373 ASB1 1.09 20.9 0.75 4.37e-63 Multiple system atrophy; LIHC cis rs712039 0.652 rs7226252 chr17:35794912 C/G cg16670864 chr17:35848621 DUSP14 0.34 5.91 0.3 8.19e-9 Tuberculosis; LIHC trans rs10506458 1.000 rs73128794 chr12:63445313 C/T cg22491629 chr6:157744540 C6orf35 -0.58 -10.07 -0.48 4.71e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs780096 0.565 rs8179252 chr2:27746832 A/C cg27432699 chr2:27873401 GPN1 -0.55 -8.13 -0.4 7.8e-15 Total body bone mineral density; LIHC cis rs4975616 0.804 rs459961 chr5:1337106 T/A cg07493874 chr5:1342172 CLPTM1L -0.7 -11.3 -0.52 2.19e-25 Lung cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17608500 chr1:154955711 FLAD1 0.49 7.39 0.37 1.13e-12 Pancreatic cancer; LIHC cis rs7116495 0.609 rs7942626 chr11:71703849 G/A cg10381502 chr11:71823885 C11orf51 -1.0 -8.62 -0.42 2.6e-16 Severe influenza A (H1N1) infection; LIHC cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg11645453 chr3:52864694 ITIH4 0.22 5.83 0.3 1.29e-8 Bipolar disorder; LIHC cis rs17384381 1.000 rs12140457 chr1:85860170 G/A cg16011679 chr1:85725395 C1orf52 0.83 8.63 0.42 2.35e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7572733 0.555 rs6729473 chr2:198763928 G/A cg00792783 chr2:198669748 PLCL1 0.48 6.98 0.35 1.57e-11 Dermatomyositis; LIHC cis rs1552244 0.882 rs67631672 chr3:10004768 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.76 10.3 0.49 7.37e-22 Alzheimer's disease; LIHC cis rs644799 1.000 rs472231 chr11:95532166 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.78 0.3 1.67e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9303401 0.659 rs8074016 chr17:56840587 A/G cg25039879 chr17:56429692 SUPT4H1 0.76 8.76 0.43 9.27e-17 Cognitive test performance; LIHC trans rs9836270 1.000 rs9836270 chr3:131916996 G/T cg10702113 chr3:196664466 NCBP2 -0.37 -6.11 -0.31 2.68e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs8081395 0.804 rs2777884 chr17:57830426 G/A cg02344993 chr17:57696989 CLTC -0.45 -7.29 -0.37 2.22e-12 White blood cell count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12633356 chr12:51318640 METTL7A 0.4 6.62 0.34 1.37e-10 Cognitive function; LIHC cis rs11971779 0.648 rs6467849 chr7:139080512 C/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.55 0.53 2.89e-26 Alzheimer's disease; LIHC cis rs2153535 0.580 rs2184582 chr6:8447793 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg08645402 chr16:4508243 NA 0.39 7.41 0.37 1.01e-12 Schizophrenia; LIHC cis rs1577917 0.958 rs11755642 chr6:86450066 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -11.43 -0.53 7.8e-26 Response to antipsychotic treatment; LIHC cis rs6088580 0.634 rs6088471 chr20:32932643 C/A cg08999081 chr20:33150536 PIGU -0.66 -13.1 -0.58 4.72e-32 Glomerular filtration rate (creatinine); LIHC cis rs921968 0.584 rs2305833 chr2:219305404 G/C cg02985541 chr2:219472218 PLCD4 0.45 8.35 0.41 1.69e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs7044106 0.762 rs10818471 chr9:123394045 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 10.85 0.51 9.34e-24 Hip circumference adjusted for BMI; LIHC cis rs12915189 1.000 rs4352026 chr15:91116163 A/C cg26821196 chr15:91095069 CRTC3 0.33 5.97 0.31 5.98e-9 Information processing speed; LIHC cis rs2576037 0.562 rs612519 chr18:44379490 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.65 9.74 0.47 6.22e-20 Personality dimensions; LIHC trans rs57590327 0.716 rs3772891 chr3:81776760 A/G cg21841682 chr14:69445844 ACTN1 0.45 6.1 0.31 2.94e-9 Extraversion; LIHC cis rs8180040 1.000 rs2302278 chr3:47361082 G/T cg27129171 chr3:47204927 SETD2 -0.63 -10.39 -0.49 3.8e-22 Colorectal cancer; LIHC cis rs2933343 0.700 rs789238 chr3:128636715 A/G cg24203234 chr3:128598194 ACAD9 0.45 6.29 0.32 9.77e-10 IgG glycosylation; LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg00106254 chr7:1943704 MAD1L1 -0.46 -7.59 -0.38 3.11e-13 Bipolar disorder and schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09844907 chr16:15489619 MPV17L -0.48 -7.08 -0.36 8.47e-12 Cognitive function; LIHC cis rs9303401 0.659 rs16943176 chr17:56769887 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs9420 0.961 rs7116341 chr11:57481155 G/A cg19752551 chr11:57585705 CTNND1 -0.53 -7.39 -0.37 1.16e-12 Schizophrenia; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.28 0.55 5.92e-29 Prudent dietary pattern; LIHC cis rs826838 0.967 rs1719858 chr12:39124505 C/T cg26384229 chr12:38710491 ALG10B -0.61 -8.92 -0.43 2.87e-17 Heart rate; LIHC cis rs12950390 0.853 rs67441169 chr17:45854462 T/G cg03474202 chr17:45855739 NA -0.34 -5.97 -0.31 6.05e-9 IgG glycosylation; LIHC cis rs7945705 0.967 rs7123861 chr11:8892323 G/A cg12365402 chr11:9010492 NRIP3 0.29 7.54 0.38 4.21e-13 Hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18732869 chr19:6739680 TRIP10 -0.44 -6.81 -0.35 4.34e-11 Pancreatic cancer; LIHC trans rs3780486 1.000 rs10813951 chr9:33128021 C/T cg20290983 chr6:43655470 MRPS18A -1.08 -20.65 -0.74 4.56e-62 IgG glycosylation; LIHC cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.81 7.75 0.39 1.09e-13 Platelet count; LIHC cis rs2279817 0.863 rs13375581 chr1:18016491 G/A cg21791023 chr1:18019539 ARHGEF10L -0.68 -8.05 -0.4 1.36e-14 Neuroticism; LIHC cis rs3796619 1.000 rs55741287 chr4:1094670 T/C cg27284194 chr4:1044797 NA 0.64 10.43 0.49 2.66e-22 Recombination rate (males); LIHC cis rs9581857 0.685 rs9319368 chr13:28042275 T/G cg22138327 chr13:27999177 GTF3A 0.76 6.26 0.32 1.17e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs2112347 0.502 rs34342 chr5:74934213 A/C cg02573091 chr5:74908125 NA -0.55 -6.71 -0.34 8.03e-11 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs2279817 0.735 rs11203432 chr1:17991196 A/G cg21791023 chr1:18019539 ARHGEF10L -0.42 -5.91 -0.3 8.31e-9 Neuroticism; LIHC cis rs6754311 0.731 rs6719488 chr2:136575199 G/T cg07169764 chr2:136633963 MCM6 -0.67 -9.97 -0.47 9.98e-21 Mosquito bite size; LIHC cis rs2274273 0.623 rs1187881 chr14:55489197 G/A cg01864836 chr14:55583639 NA 0.34 5.74 0.3 2.07e-8 Protein biomarker; LIHC cis rs17286411 0.777 rs4788569 chr16:71914785 A/G cg06353428 chr16:71660113 MARVELD3 0.56 7.06 0.36 9.2e-12 Blood protein levels; LIHC cis rs2836974 0.549 rs34160989 chr21:40554118 C/G cg17971929 chr21:40555470 PSMG1 0.69 5.79 0.3 1.62e-8 Cognitive function; LIHC cis rs1005277 0.505 rs719569 chr10:38154415 T/G cg25427524 chr10:38739819 LOC399744 0.65 12.6 0.56 3.54e-30 Extrinsic epigenetic age acceleration; LIHC cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg11890956 chr21:40555474 PSMG1 1.07 16.04 0.66 1.47e-43 Cognitive function; LIHC cis rs1163251 0.623 rs493427 chr1:120207482 A/T cg19096424 chr1:120255104 PHGDH -0.52 -6.49 -0.33 2.95e-10 Blood metabolite levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03627896 chr16:30934334 NCRNA00095 -0.5 -6.08 -0.31 3.14e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs116095464 0.558 rs10036253 chr5:238519 A/C cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.78e-52 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01688141 chr8:23539808 NKX3-1 0.47 6.5 0.33 2.82e-10 Pancreatic cancer; LIHC cis rs854765 0.565 rs854768 chr17:18018806 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.39 7.29 0.37 2.13e-12 Total body bone mineral density; LIHC cis rs1005277 0.528 rs2057228 chr10:38515766 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7615952 0.608 rs35668111 chr3:125544635 C/T cg05084668 chr3:125655381 ALG1L -0.34 -6.13 -0.31 2.39e-9 Blood pressure (smoking interaction); LIHC cis rs17079247 1.000 rs17079247 chr13:85665879 C/T ch.13.84760847R chr13:85862846 NA -0.51 -6.66 -0.34 1.08e-10 Bipolar disorder (mania); LIHC cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg21951975 chr1:209979733 IRF6 0.4 6.44 0.33 4e-10 Cleft lip with or without cleft palate; LIHC cis rs7520050 0.902 rs7514192 chr1:46248977 A/G cg03146154 chr1:46216737 IPP -0.41 -6.78 -0.34 5.34e-11 Red blood cell count;Reticulocyte count; LIHC cis rs61041384 0.661 rs4148858 chr12:123540022 G/A cg00376283 chr12:123451042 ABCB9 -0.6 -5.72 -0.3 2.37e-8 Schizophrenia; LIHC cis rs1461503 0.934 rs7115679 chr11:122831963 A/G cg25161029 chr11:122845972 NA 0.41 6.7 0.34 8.41e-11 Menarche (age at onset); LIHC cis rs7945705 0.967 rs10840141 chr11:8902218 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.07 0.36 8.6e-12 Hemoglobin concentration; LIHC cis rs801193 1.000 rs2003301 chr7:66147656 G/C cg14393609 chr7:65229607 NA -0.37 -5.88 -0.3 9.55e-9 Aortic root size; LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg07167872 chr1:205819463 PM20D1 0.6 8.85 0.43 4.66e-17 Menarche (age at onset); LIHC cis rs7772486 0.754 rs9497434 chr6:146260753 C/T cg05347473 chr6:146136440 FBXO30 -0.38 -6.08 -0.31 3.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6502050 0.835 rs12950475 chr17:80118924 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs4589502 0.841 rs56401320 chr15:67140517 C/G cg12317470 chr15:67143691 NA 0.58 5.94 0.31 7.01e-9 Lung cancer (smoking interaction); LIHC cis rs7619427 0.908 rs7639253 chr3:44076205 C/T cg24966902 chr3:44043705 NA 0.5 7.05 0.36 9.76e-12 Schizophrenia; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.16 -0.32 2.05e-9 Total body bone mineral density; LIHC cis rs507080 0.769 rs571001 chr11:118500173 C/T cg04173919 chr11:118528438 PHLDB1 0.32 5.86 0.3 1.11e-8 Serum metabolite levels; LIHC cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg11764359 chr7:65958608 NA 0.57 5.87 0.3 1.06e-8 Diabetic kidney disease; LIHC cis rs3806843 1.000 rs2337985 chr5:140157861 T/C cg26395211 chr5:140044315 WDR55 -0.43 -6.38 -0.33 5.6e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs9814567 0.806 rs9839705 chr3:134323819 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.8 -0.3 1.53e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4631830 0.720 rs2125771 chr10:51506957 C/T cg16070123 chr10:51489643 NA -0.38 -5.96 -0.31 6.16e-9 Prostate-specific antigen levels; LIHC cis rs9902453 0.933 rs7216487 chr17:28502642 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.05 0.44 1.07e-17 Coffee consumption (cups per day); LIHC cis rs17331151 0.573 rs11626 chr3:52873984 C/T cg04865290 chr3:52927548 TMEM110 -0.41 -6.03 -0.31 4.15e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs4919694 1.000 rs4917382 chr10:104838510 G/A cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs6430585 0.583 rs60253740 chr2:136571852 G/T cg07169764 chr2:136633963 MCM6 1.29 20.62 0.74 5.6e-62 Corneal structure; LIHC cis rs7914558 1.000 rs7094843 chr10:104806654 A/C cg15744005 chr10:104629667 AS3MT -0.39 -8.86 -0.43 4.32e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs12908161 1.000 rs35630683 chr15:85349231 T/C cg12863693 chr15:85201151 NMB 0.45 6.29 0.32 9.9e-10 Schizophrenia; LIHC cis rs4638749 0.677 rs13022268 chr2:108837320 A/G cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg03806693 chr22:41940476 POLR3H -0.91 -10.65 -0.5 4.46e-23 Vitiligo; LIHC cis rs72781680 0.678 rs11125293 chr2:24102423 A/G cg08917208 chr2:24149416 ATAD2B 0.65 6.59 0.34 1.71e-10 Lymphocyte counts; LIHC trans rs9858542 1.000 rs11709525 chr3:49690496 C/T cg21659725 chr3:3221576 CRBN -0.57 -6.31 -0.32 8.54e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs4322600 0.963 rs34332718 chr14:88287016 C/A cg16008221 chr8:17823628 PCM1 -0.42 -6.23 -0.32 1.36e-9 Breast cancer; LIHC cis rs35306767 0.953 rs10904581 chr10:964685 A/T cg20503657 chr10:835505 NA 0.89 10.61 0.5 6.2e-23 Eosinophil percentage of granulocytes; LIHC cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.79 0.3 1.63e-8 Bipolar disorder; LIHC cis rs4409675 0.576 rs6679432 chr1:28227665 T/C cg23691781 chr1:28212827 C1orf38 0.3 7.34 0.37 1.54e-12 Corneal astigmatism; LIHC cis rs7589728 0.748 rs35051888 chr2:88482258 G/A cg07952391 chr2:88470173 THNSL2 0.76 7.81 0.39 6.93e-14 Plasma clusterin levels; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11829380 chr17:5323521 RPAIN;NUP88 -0.46 -6.18 -0.32 1.83e-9 Immature fraction of reticulocytes; LIHC cis rs2204008 0.502 rs2387275 chr12:38142836 G/A cg26384229 chr12:38710491 ALG10B 0.85 10.59 0.5 7.57e-23 Bladder cancer; LIHC cis rs11608355 0.705 rs6663 chr12:109886603 G/A cg05360138 chr12:110035743 NA 0.77 8.87 0.43 4.24e-17 Neuroticism; LIHC cis rs796364 0.806 rs203765 chr2:200903020 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.78 -8.65 -0.42 1.97e-16 Schizophrenia; LIHC cis rs1552244 0.832 rs3732968 chr3:10013273 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.64 -9.37 -0.45 1.05e-18 Alzheimer's disease; LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg11062466 chr8:58055876 NA 0.49 7.22 0.36 3.4e-12 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.818 rs11204702 chr1:150663507 C/A cg13175981 chr1:150552382 MCL1 0.52 8.08 0.4 1.15e-14 Tonsillectomy; LIHC cis rs1577917 1.000 rs791856 chr6:86681841 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.43 8.21 0.41 4.68e-15 Response to antipsychotic treatment; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -8.01 -0.4 1.84e-14 Lymphocyte counts; LIHC cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg02187348 chr16:89574699 SPG7 0.63 9.98 0.47 9.57e-21 Multiple myeloma (IgH translocation); LIHC cis rs2257205 0.667 rs11653526 chr17:56761417 G/A cg05425664 chr17:57184151 TRIM37 -0.63 -6.79 -0.34 5.06e-11 Pancreatic cancer; LIHC cis rs6952808 1.000 rs12699404 chr7:1894022 A/T cg22963979 chr7:1858916 MAD1L1 -0.47 -7.39 -0.37 1.12e-12 Bipolar disorder and schizophrenia; LIHC cis rs5769765 0.955 rs9616394 chr22:50314927 G/C cg09182678 chr22:50328711 NA -0.46 -6.68 -0.34 9.66e-11 Schizophrenia; LIHC cis rs12477438 0.520 rs6542870 chr2:99796638 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.21 0.61 2.47e-36 Chronic sinus infection; LIHC cis rs600806 0.778 rs11101962 chr1:110014187 A/T cg23091122 chr1:110024289 SYPL2 -0.44 -6.09 -0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs9649465 1.000 rs13230338 chr7:123373622 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.25e-15 Migraine; LIHC cis rs1775715 0.870 rs1615256 chr10:32254101 T/C cg14930904 chr10:32216787 ARHGAP12 0.4 7.02 0.35 1.21e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs1997103 1.000 rs10228182 chr7:55406695 A/T cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7187994 0.895 rs12933276 chr16:84770867 C/T cg07647771 chr16:84786436 USP10 -0.33 -6.02 -0.31 4.44e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg06481639 chr22:41940642 POLR3H 0.6 5.76 0.3 1.88e-8 Vitiligo; LIHC cis rs9818758 0.556 rs9835439 chr3:49220330 G/C cg06212747 chr3:49208901 KLHDC8B -0.71 -6.19 -0.32 1.73e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7552404 0.961 rs211710 chr1:76109038 G/A cg10523679 chr1:76189770 ACADM -0.65 -8.91 -0.43 2.99e-17 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2506155 0.525 rs56242597 chr10:33528271 T/C cg03349118 chr8:59572480 NSMAF -0.6 -6.35 -0.32 6.96e-10 Migraine; LIHC cis rs10423674 0.526 rs11085241 chr19:18828546 G/A cg16673477 chr19:18812017 CRTC1 -0.41 -6.5 -0.33 2.82e-10 Menarche (age at onset); LIHC cis rs929354 0.557 rs62491947 chr7:156960813 G/A cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC trans rs2727020 0.857 rs1917324 chr11:49371759 G/C cg03929089 chr4:120376271 NA -0.66 -9.89 -0.47 1.92e-20 Coronary artery disease; LIHC cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg15691649 chr6:25882328 NA -0.42 -6.7 -0.34 8.62e-11 Height; LIHC cis rs595982 0.702 rs623520 chr19:49369943 A/G cg21252483 chr19:49399788 TULP2 -0.46 -7.61 -0.38 2.71e-13 Red cell distribution width; LIHC cis rs539096 0.500 rs2906457 chr1:44338575 A/C cg12908607 chr1:44402522 ARTN -0.48 -8.26 -0.41 3.14e-15 Intelligence (multi-trait analysis); LIHC cis rs708547 0.599 rs1718864 chr4:57887471 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.45 6.59 0.34 1.62e-10 Response to bleomycin (chromatid breaks); LIHC cis rs6500602 0.647 rs4785967 chr16:4523208 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 7.86 0.39 4.98e-14 Schizophrenia; LIHC cis rs34540877 1.000 rs11666270 chr19:33146471 A/G cg22980127 chr19:33182716 NUDT19 -0.86 -5.96 -0.31 6.39e-9 Red cell distribution width; LIHC cis rs11190604 0.697 rs10748795 chr10:102194818 A/T cg07080220 chr10:102295463 HIF1AN -0.49 -7.2 -0.36 3.93e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3892630 0.824 rs12327732 chr19:33221767 C/T cg22980127 chr19:33182716 NUDT19 1.0 11.72 0.54 6.83e-27 Red blood cell traits; LIHC cis rs2731664 0.792 rs652242 chr5:176873010 C/G cg23176889 chr5:176863531 GRK6 -0.72 -13.06 -0.58 6.65e-32 Intelligence (multi-trait analysis); LIHC cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg11301795 chr4:187892539 NA -0.26 -7.01 -0.35 1.26e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1144333 0.655 rs12401729 chr1:76336586 T/G cg10523679 chr1:76189770 ACADM 0.45 6.01 0.31 4.88e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs3806843 0.676 rs778593 chr5:140027216 T/C cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.63e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs9531686 1.000 rs7319821 chr13:85548207 G/A cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.29 0.32 9.79e-10 Anorexia nervosa; LIHC cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg06238570 chr21:40685208 BRWD1 -0.55 -9.29 -0.45 1.88e-18 Cognitive function; LIHC cis rs875971 1.000 rs811880 chr7:65818646 T/C cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs57221529 0.766 rs72706606 chr5:558609 T/C cg09021430 chr5:549028 NA -0.46 -9.13 -0.44 5.9e-18 Lung disease severity in cystic fibrosis; LIHC cis rs6952808 0.534 rs1113736 chr7:1992992 T/C cg02951883 chr7:2050386 MAD1L1 -0.6 -9.67 -0.46 1.04e-19 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg14393609 chr7:65229607 NA 0.44 6.56 0.33 2.04e-10 Aortic root size; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02254876 chr3:42922351 NA -0.49 -6.27 -0.32 1.11e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3768617 0.811 rs10911205 chr1:183009277 C/A ch.1.3577855R chr1:183094577 LAMC1 0.47 7.48 0.37 6.42e-13 Fuchs's corneal dystrophy; LIHC cis rs9918079 0.542 rs1789 chr4:15664535 G/A cg21123203 chr4:15471301 CC2D2A -0.45 -7.19 -0.36 4.13e-12 Obesity-related traits; LIHC cis rs2836974 0.644 rs2836986 chr21:40702136 A/C cg11890956 chr21:40555474 PSMG1 -0.45 -7.29 -0.37 2.18e-12 Cognitive function; LIHC cis rs9818758 0.607 rs113186424 chr3:49272726 T/C cg07636037 chr3:49044803 WDR6 -0.79 -8.19 -0.4 5.34e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9911578 1.000 rs2567911 chr17:56734977 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.575 rs6950330 chr7:1953606 T/C cg02951883 chr7:2050386 MAD1L1 -0.5 -7.58 -0.38 3.36e-13 Bipolar disorder and schizophrenia; LIHC cis rs17001868 0.568 rs9611325 chr22:40782490 G/A cg07138101 chr22:40742427 ADSL 0.55 6.45 0.33 3.89e-10 Mammographic density (dense area); LIHC cis rs1003719 0.788 rs13050757 chr21:38465345 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs7927592 0.871 rs12941 chr11:68382193 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.21 -0.32 1.57e-9 Total body bone mineral density; LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg14709524 chr16:89940631 TCF25 0.59 7.64 0.38 2.24e-13 Skin colour saturation; LIHC cis rs887797 0.557 rs8080721 chr17:64585357 C/T cg27019712 chr17:64599478 PRKCA -0.39 -6.84 -0.35 3.61e-11 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC cis rs12986413 0.651 rs2238612 chr19:2149694 C/T cg09261902 chr19:2140048 AP3D1 -0.42 -6.98 -0.35 1.54e-11 Height; LIHC cis rs2354432 0.556 rs6593777 chr1:146884013 C/G cg25205988 chr1:146714368 CHD1L 0.79 8.68 0.43 1.59e-16 Mitochondrial DNA levels; LIHC cis rs826838 1.000 rs826889 chr12:39101076 G/A cg26384229 chr12:38710491 ALG10B -0.58 -8.62 -0.42 2.57e-16 Heart rate; LIHC cis rs9309711 0.621 rs7586472 chr2:3473670 G/A cg10845886 chr2:3471009 TTC15 -0.44 -8.32 -0.41 2.09e-15 Neurofibrillary tangles; LIHC cis rs6570726 0.846 rs446031 chr6:145885592 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.54 0.53 2.93e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs370915 1.000 rs370915 chr4:187818256 C/G cg19519643 chr4:187840862 NA -0.39 -6.63 -0.34 1.29e-10 Gout; LIHC cis rs17106184 1.000 rs58791125 chr1:51342856 G/A cg07174182 chr1:51127561 FAF1 -0.61 -6.84 -0.35 3.57e-11 Type 2 diabetes; LIHC cis rs9814567 1.000 rs12490835 chr3:134223730 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.86 -0.3 1.06e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7635838 0.892 rs9852530 chr3:11466469 C/T cg00170343 chr3:11313890 ATG7 0.43 6.77 0.34 5.46e-11 HDL cholesterol; LIHC cis rs3749237 0.595 rs3924462 chr3:49524236 T/G cg07636037 chr3:49044803 WDR6 0.56 8.46 0.42 7.75e-16 Resting heart rate; LIHC cis rs2153535 0.580 rs2327064 chr6:8454052 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.17 0.55 1.54e-28 Motion sickness; LIHC cis rs1355223 0.583 rs1553757 chr11:34867089 G/A cg24088639 chr11:34937564 PDHX;APIP -0.39 -5.97 -0.31 5.98e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg20302342 chr1:156215951 PAQR6 0.32 6.2 0.32 1.65e-9 Tonsillectomy; LIHC cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg25894440 chr7:65020034 NA 0.55 6.21 0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs11122272 0.735 rs2808602 chr1:231537303 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.18 0.44 4.06e-18 Hemoglobin concentration; LIHC cis rs986417 0.786 rs1254273 chr14:60843581 C/A cg27398547 chr14:60952738 C14orf39 -0.79 -9.02 -0.44 1.36e-17 Gut microbiota (bacterial taxa); LIHC cis rs3008870 0.755 rs2815364 chr1:67498384 C/T cg02640540 chr1:67518911 SLC35D1 0.45 6.99 0.35 1.42e-11 Lymphocyte percentage of white cells; LIHC cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg11941060 chr3:133502564 NA -0.4 -5.84 -0.3 1.21e-8 Iron status biomarkers; LIHC trans rs12643302 0.634 rs6553566 chr4:172373998 G/C cg18857951 chr14:94395516 FAM181A 0.22 6.22 0.32 1.49e-9 Facial morphology (factor 3, length of philtrum); LIHC cis rs903552 1.000 rs12903048 chr15:102006325 G/T cg06707286 chr15:102010195 PCSK6 -0.44 -6.26 -0.32 1.13e-9 Diabetic kidney disease; LIHC trans rs11098499 0.863 rs7664986 chr4:120429952 A/C cg25214090 chr10:38739885 LOC399744 0.59 9.55 0.46 2.59e-19 Corneal astigmatism; LIHC cis rs477692 0.569 rs1711670 chr10:131281115 A/G cg19680672 chr10:131412579 MGMT -0.43 -6.41 -0.33 4.97e-10 Response to temozolomide; LIHC cis rs10771431 0.935 rs1117735 chr12:9372728 G/A cg08997352 chr12:9597637 DDX12 -0.51 -7.37 -0.37 1.31e-12 Breast size; LIHC cis rs7116495 0.737 rs7101553 chr11:71753903 C/T cg26138937 chr11:71823887 C11orf51 -1.34 -10.79 -0.5 1.53e-23 Severe influenza A (H1N1) infection; LIHC cis rs2180341 1.000 rs9388561 chr6:127634921 C/T cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs919433 0.929 rs4850788 chr2:198182940 G/A cg03934865 chr2:198174659 NA -0.59 -9.34 -0.45 1.27e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7551222 0.752 rs11240756 chr1:204482594 C/T cg20240347 chr1:204465584 NA -0.35 -7.48 -0.37 6.51e-13 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06425136 chr16:31040922 NA -0.38 -6.54 -0.33 2.22e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs17401966 1.000 rs12755094 chr1:10305711 T/C cg19773385 chr1:10388646 KIF1B -0.47 -8.18 -0.4 5.75e-15 Hepatocellular carcinoma; LIHC cis rs965469 1.000 rs6037554 chr20:3315613 G/A cg25506879 chr20:3388711 C20orf194 -0.58 -7.06 -0.36 9.15e-12 IFN-related cytopenia; LIHC cis rs4450131 0.522 rs3781453 chr10:126348761 T/C cg20435097 chr10:126320824 FAM53B 0.67 12.35 0.56 3.21e-29 White blood cell count (basophil); LIHC cis rs7572733 0.534 rs696817 chr2:198722225 A/G cg10820045 chr2:198174542 NA 0.47 7.01 0.35 1.27e-11 Dermatomyositis; LIHC cis rs9467711 0.606 rs9379901 chr6:26603866 T/C cg09904177 chr6:26538194 HMGN4 -0.53 -5.72 -0.3 2.37e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs5769765 1.000 rs5770741 chr22:50270215 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06441946 chr5:145583671 RBM27 0.48 6.68 0.34 9.44e-11 Pancreatic cancer; LIHC cis rs9911578 1.000 rs6503866 chr17:56619581 C/T cg05425664 chr17:57184151 TRIM37 0.58 8.65 0.42 1.97e-16 Intelligence (multi-trait analysis); LIHC cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg19626725 chr5:178986131 RUFY1 -0.38 -5.85 -0.3 1.16e-8 Lung cancer; LIHC cis rs754466 0.510 rs10824579 chr10:79590685 C/T cg17075019 chr10:79541650 NA -0.6 -10.76 -0.5 1.95e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3762637 1.000 rs7644540 chr3:122210052 C/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27022615 chr11:70049105 FADD 0.44 6.34 0.32 7.26e-10 Pancreatic cancer; LIHC cis rs738322 0.967 rs133024 chr22:38574066 C/T cg25457927 chr22:38595422 NA 0.26 6.48 0.33 3.12e-10 Cutaneous nevi; LIHC cis rs12477438 0.501 rs13033012 chr2:99795149 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs7520050 0.966 rs12021587 chr1:46472759 G/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.0 0.31 4.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1395 0.744 rs57881048 chr2:27474165 T/C cg23587288 chr2:27483067 SLC30A3 -0.35 -6.59 -0.34 1.67e-10 Blood metabolite levels; LIHC cis rs523522 0.962 rs10774549 chr12:120891172 C/T cg12219531 chr12:120966889 COQ5 0.65 12.48 0.56 1e-29 High light scatter reticulocyte count; LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg07677032 chr17:61819896 STRADA 0.44 6.43 0.33 4.31e-10 Prudent dietary pattern; LIHC cis rs11758351 0.929 rs75475698 chr6:26190609 C/G cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs10256972 0.967 rs4723338 chr7:1036241 A/G cg04025307 chr7:1156635 C7orf50 0.49 8.2 0.41 4.8e-15 Longevity;Endometriosis; LIHC cis rs7503168 1.000 rs16971227 chr17:33949222 G/A cg20932281 chr17:33905541 PEX12 0.54 7.01 0.35 1.24e-11 Plateletcrit; LIHC cis rs875971 0.545 rs75840613 chr7:65841386 G/A cg11764359 chr7:65958608 NA 0.59 8.43 0.41 9.64e-16 Aortic root size; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg12467960 chr11:68201194 LRP5 0.42 6.17 0.32 1.94e-9 Immature fraction of reticulocytes; LIHC cis rs9649213 0.593 rs3801263 chr7:97965016 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.87e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs637571 0.522 rs491973 chr11:65727301 A/G cg02202077 chr11:65769826 EIF1AD;BANF1 0.38 5.79 0.3 1.59e-8 Eosinophil percentage of white cells; LIHC cis rs11190604 0.767 rs10883485 chr10:102174805 G/C cg07080220 chr10:102295463 HIF1AN 0.44 6.02 0.31 4.49e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.48 -6.91 -0.35 2.38e-11 Prostate cancer; LIHC cis rs5769765 0.955 rs61136468 chr22:50312679 A/G cg26441486 chr22:50317300 CRELD2 0.36 6.47 0.33 3.32e-10 Schizophrenia; LIHC cis rs6066825 0.644 rs4810864 chr20:47319142 G/C cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.59e-12 Colorectal cancer; LIHC cis rs72627509 0.680 rs3733309 chr4:57857188 A/G cg26694713 chr4:57773883 REST 0.66 8.72 0.43 1.19e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg00656387 chr3:40428638 ENTPD3 0.42 6.95 0.35 1.81e-11 Renal cell carcinoma; LIHC cis rs4604732 0.536 rs4925674 chr1:247636906 C/T cg02104434 chr1:247694406 LOC148824;OR2C3 0.25 5.97 0.31 5.97e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs1878931 0.501 rs9302871 chr16:3415512 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.71 10.61 0.5 6.32e-23 Body mass index (adult); LIHC cis rs9549367 0.713 rs4907599 chr13:113861441 C/T cg18105134 chr13:113819100 PROZ 0.64 11.2 0.52 5.02e-25 Platelet distribution width; LIHC cis rs4700695 0.841 rs27132 chr5:65288791 A/G cg21114390 chr5:65439923 SFRS12 0.44 5.74 0.3 2.11e-8 Facial morphology (factor 19); LIHC cis rs1559088 0.948 rs12610071 chr19:33582687 A/C cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs11148252 0.574 rs3742297 chr13:53278067 T/C cg12458913 chr13:53173898 NA 0.5 8.04 0.4 1.5e-14 Lewy body disease; LIHC cis rs780096 0.546 rs715325 chr2:27725572 C/A cg27432699 chr2:27873401 GPN1 -0.53 -7.58 -0.38 3.33e-13 Total body bone mineral density; LIHC cis rs933688 0.526 rs2973468 chr5:90540879 A/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 -0.4 -5.92 -0.3 7.77e-9 Smoking behavior; LIHC cis rs7618501 0.966 rs13085679 chr3:49869631 G/A cg24110177 chr3:50126178 RBM5 -0.47 -7.22 -0.36 3.32e-12 Intelligence (multi-trait analysis); LIHC cis rs155076 1.000 rs564685 chr13:21846879 A/G cg11317459 chr13:21872234 NA -1.17 -13.06 -0.58 6.87e-32 White matter hyperintensity burden; LIHC cis rs9325144 0.560 rs1601745 chr12:38647828 G/A cg26384229 chr12:38710491 ALG10B -0.48 -7.49 -0.38 5.97e-13 Morning vs. evening chronotype; LIHC cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg20607798 chr8:58055168 NA -0.59 -7.14 -0.36 5.7e-12 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.641 rs2748489 chr6:146331287 T/G cg05347473 chr6:146136440 FBXO30 0.46 7.01 0.35 1.31e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs10883723 0.962 rs1056741 chr10:104236640 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 11.43 0.53 7.85e-26 Allergic disease (asthma, hay fever or eczema); LIHC cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 7.06 0.36 9.33e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs765787 0.530 rs13329228 chr15:45533017 C/T cg25801113 chr15:45476975 SHF 0.38 6.55 0.33 2.1e-10 Uric acid levels; LIHC cis rs7395581 0.918 rs326214 chr11:47298360 G/A cg25783544 chr11:47291846 MADD -0.4 -5.87 -0.3 1.04e-8 HDL cholesterol; LIHC cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs11958404 0.860 rs6885815 chr5:157437253 C/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs9399135 0.967 rs1590975 chr6:135352088 C/T cg24558204 chr6:135376177 HBS1L 0.41 6.88 0.35 2.86e-11 Red blood cell count; LIHC cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg14393609 chr7:65229607 NA 0.44 6.48 0.33 3.28e-10 Aortic root size; LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg01516881 chr6:292596 DUSP22 -0.5 -6.37 -0.33 6.27e-10 Menopause (age at onset); LIHC cis rs807669 0.835 rs1780639 chr22:19174603 T/C cg02655711 chr22:19163373 SLC25A1 0.73 11.2 0.52 5.32e-25 Metabolite levels; LIHC trans rs1814175 0.529 rs10839396 chr11:49852406 G/T cg18944383 chr4:111397179 ENPEP -0.38 -8.9 -0.43 3.31e-17 Height; LIHC cis rs17401966 0.964 rs6674843 chr1:10458378 A/T cg19773385 chr1:10388646 KIF1B -0.46 -7.13 -0.36 6.02e-12 Hepatocellular carcinoma; LIHC cis rs1552244 0.882 rs17050672 chr3:10025463 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.8 10.47 0.49 1.92e-22 Alzheimer's disease; LIHC cis rs78545713 0.649 rs77362785 chr6:26232351 G/A cg16070018 chr6:26224392 HIST1H3E 0.8 7.54 0.38 4.2e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg13395646 chr4:1353034 KIAA1530 0.41 6.49 0.33 2.97e-10 Obesity-related traits; LIHC cis rs1799949 0.965 rs9646413 chr17:41426157 A/G cg05368731 chr17:41323189 NBR1 0.66 10.66 0.5 4.18e-23 Menopause (age at onset); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg19712745 chr6:131275789 EPB41L2 -0.27 -6.31 -0.32 8.52e-10 Calcium levels; LIHC cis rs10504073 0.669 rs57085792 chr8:50018355 T/C cg00325661 chr8:49890786 NA 0.32 7.23 0.36 3.19e-12 Blood metabolite ratios; LIHC cis rs2427308 0.607 rs1741635 chr20:60938197 C/G cg03945807 chr20:60948434 NA -0.46 -6.19 -0.32 1.76e-9 Colorectal cancer; LIHC cis rs1707322 0.752 rs28545085 chr1:46201950 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.3 0.37 2.04e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03523744 chr5:108746281 PJA2 0.42 6.49 0.33 3.08e-10 Pancreatic cancer; LIHC cis rs7937890 0.559 rs4369365 chr11:14444515 C/G cg22961513 chr11:14280813 SPON1 -0.43 -6.38 -0.33 5.89e-10 Mitochondrial DNA levels; LIHC cis rs6952808 0.595 rs3800917 chr7:2167939 A/G cg21782813 chr7:2030301 MAD1L1 -0.39 -6.63 -0.34 1.35e-10 Bipolar disorder and schizophrenia; LIHC cis rs644799 0.930 rs3802764 chr11:95514599 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.54e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7100689 0.577 rs756208 chr10:82041751 A/G cg00277334 chr10:82204260 NA -0.53 -6.47 -0.33 3.37e-10 Post bronchodilator FEV1; LIHC cis rs9309473 1.000 rs11899902 chr2:73631564 G/A cg20560298 chr2:73613845 ALMS1 -0.59 -6.87 -0.35 3.07e-11 Metabolite levels; LIHC cis rs1580019 0.522 rs10951340 chr7:32562408 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.86 0.43 4.49e-17 Cognitive ability; LIHC cis rs10463316 0.862 rs1983171 chr5:150778691 A/G cg03212797 chr5:150827313 SLC36A1 -0.48 -7.33 -0.37 1.67e-12 Metabolite levels (Pyroglutamine); LIHC cis rs3806843 0.706 rs2563302 chr5:140079051 T/C cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4689388 0.926 rs5018648 chr4:6292818 C/G cg25554036 chr4:6271136 WFS1 -0.51 -7.3 -0.37 2.1e-12 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs2549003 1.000 rs2070731 chr5:131819798 T/C cg21138405 chr5:131827807 IRF1 0.35 8.8 0.43 6.83e-17 Asthma (sex interaction); LIHC cis rs7945705 0.902 rs1560569 chr11:8939887 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.4 -6.57 -0.33 1.9e-10 Hemoglobin concentration; LIHC cis rs422249 0.511 rs102274 chr11:61557826 T/C cg27386326 chr11:61587980 NA 0.69 14.74 0.62 1.99e-38 Trans fatty acid levels; LIHC cis rs611744 0.868 rs612722 chr8:109194850 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs2290405 0.527 rs6829987 chr4:932974 C/G cg04824913 chr4:887549 GAK -0.55 -8.39 -0.41 1.26e-15 Systemic sclerosis; LIHC cis rs10508774 1.000 rs12243271 chr10:32746639 G/C cg01819863 chr10:32635814 EPC1 0.65 6.1 0.31 2.87e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs67311347 1.000 rs7612015 chr3:40399974 A/C cg13409248 chr3:40428643 ENTPD3 0.4 6.64 0.34 1.2e-10 Renal cell carcinoma; LIHC cis rs2303759 0.676 rs7248378 chr19:49908144 C/A cg24324837 chr19:49891574 CCDC155 0.41 6.41 0.33 4.75e-10 Multiple sclerosis; LIHC trans rs1499614 1.000 rs1267817 chr7:66110040 G/T cg07424592 chr7:64974309 NA 0.78 8.92 0.43 2.84e-17 Gout; LIHC cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC cis rs4631830 0.828 rs10763567 chr10:51538169 C/A cg20129853 chr10:51489980 NA 0.41 8.96 0.44 2.11e-17 Prostate-specific antigen levels; LIHC cis rs7715806 0.500 rs72633983 chr5:75002845 C/T cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1182436 1 rs1182436 chr7:157027753 T/C cg17757837 chr7:157058334 UBE3C -0.57 -5.89 -0.3 9.45e-9 Type 2 diabetes; LIHC cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg25894440 chr7:65020034 NA -0.49 -5.73 -0.3 2.23e-8 Diabetic kidney disease; LIHC cis rs875971 0.895 rs12698520 chr7:65918707 C/A cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.95e-11 Aortic root size; LIHC cis rs7116495 1.000 rs674735 chr11:71560580 A/G cg26138937 chr11:71823887 C11orf51 0.67 6.43 0.33 4.3e-10 Severe influenza A (H1N1) infection; LIHC cis rs734999 0.545 rs10910111 chr1:2542653 A/G cg18854424 chr1:2615690 NA 0.33 7.23 0.36 3.22e-12 Ulcerative colitis; LIHC cis rs2839627 0.561 rs9808758 chr21:44262390 G/C cg18192155 chr21:44258298 NA 0.38 5.72 0.3 2.29e-8 Information processing speed; LIHC cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg24531977 chr5:56204891 C5orf35 0.63 8.95 0.44 2.34e-17 Initial pursuit acceleration; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg00656387 chr3:40428638 ENTPD3 -0.47 -8.32 -0.41 2.16e-15 Renal cell carcinoma; LIHC cis rs1008375 1.000 rs10939740 chr4:17617490 T/C cg16339924 chr4:17578868 LAP3 0.55 7.22 0.36 3.49e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs1475911 1.000 rs17114359 chr21:43510437 A/C cg19766460 chr21:43528205 UMODL1;C21orf128 0.69 9.8 0.47 3.66e-20 IgG glycosylation; LIHC cis rs12477438 0.508 rs2516832 chr2:99771268 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.26 0.61 1.54e-36 Chronic sinus infection; LIHC cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg17971929 chr21:40555470 PSMG1 -0.47 -7.05 -0.36 9.86e-12 Cognitive function; LIHC cis rs8072100 1.000 rs3809868 chr17:45750596 G/A cg08085267 chr17:45401833 C17orf57 0.58 8.44 0.42 9.01e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs13256369 1.000 rs13266699 chr8:8570313 A/T cg00074818 chr8:8560427 CLDN23 -0.45 -7.41 -0.37 9.95e-13 Obesity-related traits; LIHC cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg18230493 chr5:56204884 C5orf35 -0.47 -6.6 -0.34 1.57e-10 Initial pursuit acceleration; LIHC cis rs8180040 0.800 rs7632501 chr3:47268306 T/C cg27129171 chr3:47204927 SETD2 -0.56 -9.11 -0.44 6.87e-18 Colorectal cancer; LIHC cis rs11792861 0.781 rs2297581 chr9:111755008 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.75 0.43 1.01e-16 Menarche (age at onset); LIHC cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.6 0.34 1.57e-10 Bipolar disorder; LIHC cis rs72781680 0.566 rs6713979 chr2:23899876 A/G cg08917208 chr2:24149416 ATAD2B 0.62 6.13 0.31 2.41e-9 Lymphocyte counts; LIHC cis rs6121246 0.567 rs6060344 chr20:30207316 A/G cg13852791 chr20:30311386 BCL2L1 0.73 6.37 0.33 6.07e-10 Mean corpuscular hemoglobin; LIHC cis rs6964587 0.967 rs13233496 chr7:91813035 T/C cg17063962 chr7:91808500 NA 1.01 19.67 0.73 3.61e-58 Breast cancer; LIHC cis rs6430585 0.528 rs10496738 chr2:136751488 C/T cg07305463 chr2:136567211 LCT -0.38 -5.84 -0.3 1.2e-8 Corneal structure; LIHC cis rs7512552 0.582 rs834233 chr1:150354276 G/A cg15654264 chr1:150340011 RPRD2 0.66 10.41 0.49 3.11e-22 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs1881396 0.947 rs10173720 chr2:27855397 A/T cg27432699 chr2:27873401 GPN1 -0.49 -7.54 -0.38 4.38e-13 Nonalcoholic fatty liver disease; LIHC cis rs16828019 0.852 rs12729586 chr1:41522377 C/A cg20697417 chr1:41786797 NA 0.31 5.82 0.3 1.35e-8 Intelligence (multi-trait analysis); LIHC cis rs2289583 0.573 rs12148555 chr15:75395475 C/T cg15902774 chr15:75289873 SCAMP5 0.33 5.86 0.3 1.06e-8 Systemic lupus erythematosus; LIHC cis rs17152411 1.000 rs11245423 chr10:126588435 C/A cg07906193 chr10:126599966 NA 0.42 6.61 0.34 1.48e-10 Height; LIHC cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg23205692 chr1:25664452 TMEM50A 0.37 5.75 0.3 1.94e-8 Erythrocyte sedimentation rate; LIHC cis rs2760061 0.505 rs708109 chr1:228190657 C/T cg01200585 chr1:228362443 C1orf69 0.5 6.32 0.32 8.19e-10 Diastolic blood pressure; LIHC cis rs600806 0.888 rs4970749 chr1:109873573 G/A cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.33 -0.37 1.71e-12 Intelligence (multi-trait analysis); LIHC cis rs7914558 0.505 rs12260436 chr10:104741114 A/C cg04362960 chr10:104952993 NT5C2 0.45 6.56 0.33 1.99e-10 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7618501 0.633 rs6446189 chr3:50008566 A/G cg21467203 chr3:49911342 NA -0.45 -8.05 -0.4 1.37e-14 Intelligence (multi-trait analysis); LIHC cis rs769267 0.930 rs10414830 chr19:19562332 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.93 0.39 3.07e-14 Tonsillectomy; LIHC cis rs2749592 0.725 rs9417245 chr10:37826322 C/T cg25427524 chr10:38739819 LOC399744 0.46 7.62 0.38 2.6e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg03854865 chr6:26224070 HIST1H3E 0.65 7.72 0.39 1.33e-13 Gout;Renal underexcretion gout; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg03395511 chr6:291903 DUSP22 -0.51 -6.7 -0.34 8.71e-11 Menopause (age at onset); LIHC trans rs11088226 0.692 rs2833863 chr21:33886986 A/G cg09050820 chr6:167586206 TCP10L2 0.46 6.88 0.35 2.79e-11 Gastritis; LIHC cis rs12220238 1.000 rs11000901 chr10:75919971 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10911232 0.507 rs4266836 chr1:183029070 T/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.61 0.5 6.21e-23 Hypertriglyceridemia; LIHC cis rs12586317 0.547 rs112510746 chr14:35491833 T/G cg05294307 chr14:35346193 BAZ1A -0.5 -7.52 -0.38 4.91e-13 Psoriasis; LIHC cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg18252515 chr7:66147081 NA 1.3 16.95 0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs7903847 1.000 rs7903847 chr10:99154982 T/C cg06359132 chr10:99160096 RRP12 -0.41 -6.12 -0.31 2.5e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1865760 1.000 rs9358893 chr6:25921761 A/G cg03517284 chr6:25882590 NA -0.38 -5.76 -0.3 1.83e-8 Height; LIHC cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg17554472 chr22:41940697 POLR3H 0.56 5.99 0.31 5.18e-9 Vitiligo; LIHC cis rs8062405 1.000 rs7198606 chr16:28875122 T/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2153535 0.580 rs1410766 chr6:8525360 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.6 0.42 2.93e-16 Motion sickness; LIHC cis rs735396 0.627 rs2264778 chr12:121450354 C/A cg25281562 chr12:121454272 C12orf43 0.47 8.0 0.4 2.01e-14 N-glycan levels; LIHC cis rs898097 0.812 rs55794221 chr17:80849003 G/A cg15369054 chr17:80825471 TBCD 0.42 5.99 0.31 5.45e-9 Breast cancer; LIHC cis rs9640161 0.750 rs3735169 chr7:150034378 A/G cg10018233 chr7:150070692 REPIN1 0.56 8.61 0.42 2.75e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs1559088 0.948 rs9304844 chr19:33579935 G/T cg17764715 chr19:33622953 WDR88 0.46 6.83 0.35 3.89e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4713118 0.955 rs9368529 chr6:27684631 G/A cg20933634 chr6:27740509 NA 0.47 6.31 0.32 8.82e-10 Parkinson's disease; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg01171360 chr6:293285 DUSP22 -0.46 -6.85 -0.35 3.44e-11 Menopause (age at onset); LIHC cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg08280861 chr8:58055591 NA 0.54 6.13 0.31 2.45e-9 Developmental language disorder (linguistic errors); LIHC cis rs1801251 1.000 rs1044480 chr2:233633736 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.44 0.53 7.17e-26 Coronary artery disease; LIHC cis rs9399135 0.660 rs4440481 chr6:135276696 A/G cg22676075 chr6:135203613 NA 0.39 6.22 0.32 1.42e-9 Red blood cell count; LIHC cis rs8177253 0.555 rs4481157 chr3:133464684 G/A cg24879335 chr3:133465180 TF 0.31 6.98 0.35 1.56e-11 Iron status biomarkers; LIHC cis rs7520050 0.778 rs3014218 chr1:46026328 A/C cg24296786 chr1:45957014 TESK2 0.42 6.1 0.31 2.82e-9 Red blood cell count;Reticulocyte count; LIHC cis rs9790314 1.000 rs336548 chr3:161058412 T/C cg03342759 chr3:160939853 NMD3 -0.69 -8.39 -0.41 1.25e-15 Morning vs. evening chronotype; LIHC cis rs10791097 0.694 rs1893017 chr11:130756253 C/T cg22079354 chr11:130786696 SNX19 0.41 5.82 0.3 1.35e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7044106 0.537 rs10818474 chr9:123489964 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 10.06 0.48 5.19e-21 Hip circumference adjusted for BMI; LIHC trans rs7618501 0.538 rs9856572 chr3:50109073 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.57 -9.28 -0.45 2e-18 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg14671364 chr1:107599128 PRMT6 -0.47 -6.93 -0.35 2.04e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs16828019 0.852 rs12022978 chr1:41554088 A/G cg03387723 chr1:41708464 SCMH1 -0.41 -6.76 -0.34 5.83e-11 Intelligence (multi-trait analysis); LIHC cis rs79387448 0.745 rs1403549 chr2:103110745 G/C cg09003973 chr2:102972529 NA 0.81 7.04 0.36 1.04e-11 Gut microbiota (bacterial taxa); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15072735 chr9:72375102 PTAR1 0.47 6.79 0.34 5.02e-11 Pancreatic cancer; LIHC cis rs4555082 0.957 rs2975216 chr14:105713134 T/C cg13114125 chr14:105738426 BRF1 -0.7 -9.62 -0.46 1.53e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs17152411 0.895 rs7084646 chr10:126585738 T/C cg07906193 chr10:126599966 NA 0.44 6.9 0.35 2.5e-11 Height; LIHC trans rs7618501 0.633 rs2883057 chr3:49998282 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.57 9.34 0.45 1.31e-18 Intelligence (multi-trait analysis); LIHC cis rs208520 0.526 rs7776413 chr6:66783241 A/G cg07460842 chr6:66804631 NA -1.02 -19.4 -0.72 4.36e-57 Exhaled nitric oxide output; LIHC cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg03806693 chr22:41940476 POLR3H -1.12 -13.53 -0.59 1.04e-33 Vitiligo; LIHC cis rs12291225 0.546 rs11023199 chr11:14394258 A/G cg19336497 chr11:14380999 RRAS2 -0.64 -13.15 -0.58 2.95e-32 Sense of smell; LIHC cis rs11673344 0.704 rs1644710 chr19:37417062 A/G cg27390819 chr19:37464633 NA -0.5 -6.01 -0.31 4.69e-9 Obesity-related traits; LIHC cis rs7793919 0.628 rs4720402 chr7:4780961 T/G cg09789173 chr7:4769017 FOXK1 0.73 10.52 0.49 1.28e-22 Mosquito bite size; LIHC cis rs10751667 0.666 rs7123912 chr11:963936 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.82 -0.63 1.04e-38 Alzheimer's disease (late onset); LIHC cis rs7666738 0.830 rs17027090 chr4:98897923 G/T cg05340658 chr4:99064831 C4orf37 0.66 11.83 0.54 2.58e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg03264133 chr6:25882463 NA 0.86 11.85 0.54 2.32e-27 Blood metabolite levels; LIHC cis rs1552244 0.554 rs2272121 chr3:10047680 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC cis rs8044868 0.548 rs3909541 chr16:72201119 C/T cg16558253 chr16:72132732 DHX38 0.38 6.19 0.32 1.71e-9 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg12463550 chr7:65579703 CRCP -0.66 -6.85 -0.35 3.41e-11 Diabetic kidney disease; LIHC cis rs4819052 0.808 rs2838825 chr21:46655651 C/T cg22633049 chr21:46681294 NA -0.36 -6.11 -0.31 2.72e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04238871 chr10:126431886 FAM53B 0.39 6.4 0.33 4.99e-10 Cognitive function; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03861428 chr1:17380702 SDHB 0.44 6.42 0.33 4.58e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9646954 0.542 rs4149510 chr2:101023635 G/A cg14675211 chr2:100938903 LONRF2 0.55 8.41 0.41 1.16e-15 Intelligence (multi-trait analysis); LIHC cis rs7833986 0.534 rs2667972 chr8:56906661 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.82 8.33 0.41 1.92e-15 Height; LIHC cis rs1461503 0.512 rs4259833 chr11:122809205 G/A cg25161029 chr11:122845972 NA 0.34 6.07 0.31 3.4e-9 Menarche (age at onset); LIHC cis rs36051895 0.623 rs10118434 chr9:5238460 A/G cg02405213 chr9:5042618 JAK2 -0.65 -10.48 -0.49 1.83e-22 Pediatric autoimmune diseases; LIHC cis rs8141529 0.719 rs6005916 chr22:29233342 T/C cg15103426 chr22:29168792 CCDC117 0.67 11.31 0.52 2.06e-25 Lymphocyte counts; LIHC cis rs6667605 0.506 rs10797440 chr1:2541269 A/G cg18854424 chr1:2615690 NA 0.33 7.41 0.37 9.82e-13 Inflammatory bowel disease;Ulcerative colitis; LIHC trans rs78049276 0.736 rs17612742 chr4:148414651 C/T cg13149281 chr14:23389818 RBM23;PRMT5 0.54 6.57 0.33 1.92e-10 Pulse pressure; LIHC cis rs6450176 0.909 rs11742688 chr5:53291081 C/T ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.29 -0.64 1.35e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs4919087 0.715 rs2484880 chr10:98998355 T/C cg25902810 chr10:99078978 FRAT1 -0.51 -5.91 -0.3 8.29e-9 Monocyte count; LIHC cis rs4819052 0.851 rs2838826 chr21:46655785 A/G cg11663144 chr21:46675770 NA -0.35 -6.14 -0.32 2.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs12744310 1.000 rs35318047 chr1:41755166 C/T cg03962019 chr1:41807865 NA 0.38 6.19 0.32 1.73e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs15676 0.783 rs2280843 chr9:131585069 A/G cg00228799 chr9:131580591 ENDOG 0.48 6.99 0.35 1.44e-11 Blood metabolite levels; LIHC cis rs7833790 0.700 rs28390260 chr8:82769175 A/T cg27398817 chr8:82754497 SNX16 0.31 5.75 0.3 1.99e-8 Diastolic blood pressure; LIHC cis rs10426930 0.607 rs858423 chr19:5048374 T/C cg18473234 chr19:5097819 KDM4B -0.58 -6.88 -0.35 2.94e-11 Monocyte percentage of white cells; LIHC cis rs637571 0.522 rs538954 chr11:65756808 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.25 0.45 2.45e-18 Eosinophil percentage of white cells; LIHC cis rs9612 0.718 rs346535 chr19:44251425 C/T cg08581076 chr19:44259116 C19orf61 0.59 7.77 0.39 9.53e-14 Exhaled nitric oxide output; LIHC cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7511006 0.893 rs5771104 chr22:50651839 C/T cg07895657 chr22:50616420 PANX2 -0.38 -6.85 -0.35 3.35e-11 Obesity-related traits; LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.97 0.8 4.54e-79 Prudent dietary pattern; LIHC cis rs1003719 0.788 rs2835589 chr21:38463342 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs2180341 0.814 rs6905553 chr6:127727407 A/G cg27446573 chr6:127587934 RNF146 0.79 13.09 0.58 5.05e-32 Breast cancer; LIHC cis rs1555399 0.967 rs11627207 chr14:67985000 G/T cg16224230 chr14:67978224 TMEM229B -0.24 -5.72 -0.3 2.37e-8 Parkinson's disease; LIHC cis rs7845219 0.544 rs9643351 chr8:95917290 C/T cg16049864 chr8:95962084 TP53INP1 -0.43 -6.43 -0.33 4.27e-10 Type 2 diabetes; LIHC cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg26874164 chr19:58962979 ZNF324B 0.59 8.96 0.44 2.09e-17 Uric acid clearance; LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg02951883 chr7:2050386 MAD1L1 0.76 13.37 0.59 4.41e-33 Bipolar disorder and schizophrenia; LIHC cis rs116095464 0.558 rs56043030 chr5:220917 A/G cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs2070488 0.775 rs2051213 chr3:38560254 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.69 11.32 0.52 1.93e-25 Electrocardiographic conduction measures; LIHC cis rs9517320 0.515 rs9556972 chr13:99209815 C/T cg20487152 chr13:99095054 FARP1 -0.35 -5.76 -0.3 1.9e-8 Longevity; LIHC cis rs10789491 1.000 rs4553120 chr1:47165729 C/T cg15501359 chr1:47185051 KIAA0494 0.77 11.13 0.52 9.25e-25 Response to hepatitis C treatment; LIHC cis rs6582630 0.555 rs11182217 chr12:38480030 G/A cg13010199 chr12:38710504 ALG10B 0.56 6.62 0.34 1.4e-10 Drug-induced liver injury (flucloxacillin); LIHC trans rs57221529 0.766 rs72706608 chr5:559203 C/T cg25482853 chr8:67687455 SGK3 0.67 6.65 0.34 1.14e-10 Lung disease severity in cystic fibrosis; LIHC trans rs208520 0.526 rs7775830 chr6:66755249 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.86 15.52 0.64 1.67e-41 Exhaled nitric oxide output; LIHC cis rs6867032 0.527 rs13190594 chr5:2012474 T/C cg26168224 chr5:2018326 NA 0.28 6.62 0.34 1.38e-10 Gut microbiome composition (winter); LIHC cis rs7903847 0.642 rs12359257 chr10:99136359 A/T cg06359132 chr10:99160096 RRP12 -0.42 -6.66 -0.34 1.06e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11764590 0.694 rs10241537 chr7:2083358 A/G cg23422044 chr7:1970798 MAD1L1 -0.51 -7.99 -0.4 2.07e-14 Neuroticism; LIHC trans rs116095464 0.558 rs13354585 chr5:242263 G/C cg00938859 chr5:1591904 SDHAP3 0.58 7.14 0.36 5.67e-12 Breast cancer; LIHC cis rs5769765 0.862 rs9616384 chr22:50313082 C/T cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs7098414 0.511 rs7898787 chr10:82156042 G/A cg01528321 chr10:82214614 TSPAN14 0.44 6.67 0.34 1.05e-10 Post bronchodilator FEV1; LIHC cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg03354898 chr7:1950403 MAD1L1 -0.37 -5.77 -0.3 1.73e-8 Bipolar disorder and schizophrenia; LIHC cis rs2075371 1.000 rs2544210 chr7:133971535 C/T cg11752832 chr7:134001865 SLC35B4 0.5 7.52 0.38 5.02e-13 Mean platelet volume; LIHC cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.76 0.3 1.84e-8 Menopause (age at onset); LIHC cis rs1003719 0.788 rs9981226 chr21:38452127 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.2 0.55 1.12e-28 Eye color traits; LIHC cis rs7044106 0.762 rs3904197 chr9:123480378 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.49 0.49 1.69e-22 Hip circumference adjusted for BMI; LIHC cis rs9814567 1.000 rs6787371 chr3:134254991 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs7618501 1.000 rs11709680 chr3:49745188 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.13 -0.63 6.08e-40 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.967 rs336586 chr3:161081347 G/A cg04691961 chr3:161091175 C3orf57 -0.44 -7.02 -0.35 1.22e-11 Morning vs. evening chronotype; LIHC cis rs9486715 0.790 rs2971602 chr6:97022468 C/T cg18709589 chr6:96969512 KIAA0776 -0.34 -5.95 -0.31 6.56e-9 Headache; LIHC cis rs11122272 0.766 rs2808608 chr1:231543175 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.91 -0.51 5.6e-24 Hemoglobin concentration; LIHC cis rs600806 0.778 rs2152924 chr1:110011701 G/A cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.24 -0.32 1.33e-9 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg03517284 chr6:25882590 NA -0.48 -5.87 -0.3 1.04e-8 Intelligence (multi-trait analysis); LIHC cis rs11105298 0.891 rs10858896 chr12:89920184 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.28 -0.37 2.34e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs648044 0.520 rs500629 chr11:114045560 G/T cg01914181 chr11:114070210 ZBTB16 0.49 7.22 0.36 3.3e-12 Non-glioblastoma glioma; LIHC cis rs9640161 0.750 rs3800780 chr7:150027284 C/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.55 -9.26 -0.45 2.34e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs13392177 0.684 rs11682371 chr2:219079513 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.56 -7.9 -0.39 3.86e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18598152 chr14:24020957 NA 0.41 6.1 0.31 2.93e-9 Pancreatic cancer; LIHC cis rs600806 0.778 rs10494040 chr1:110015732 C/T cg08911820 chr1:110026001 ATXN7L2 -0.58 -7.38 -0.37 1.18e-12 Intelligence (multi-trait analysis); LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg19160353 chr10:3827878 KLF6 -0.43 -6.09 -0.31 3.06e-9 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs7647973 1.000 rs10865956 chr3:49581559 C/A cg07636037 chr3:49044803 WDR6 0.53 6.57 0.33 1.88e-10 Menarche (age at onset); LIHC cis rs57920188 0.584 rs12062024 chr1:4089259 A/T cg20703997 chr1:4087676 NA -0.48 -6.34 -0.32 7.09e-10 Interleukin-17 levels; LIHC trans rs10411161 0.938 rs17778649 chr19:52381616 C/T cg22319618 chr22:45562946 NUP50 -0.53 -7.23 -0.36 3.19e-12 Breast cancer; LIHC cis rs1003719 0.591 rs1053984 chr21:38574018 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.63 -0.5 5.35e-23 Eye color traits; LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC cis rs4862307 0.688 rs6552743 chr4:184990516 C/G cg22054328 chr4:184930219 STOX2 0.34 5.81 0.3 1.46e-8 Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC trans rs4906332 1.000 rs12885234 chr14:103889181 A/G cg17675199 chr6:35436792 RPL10A 0.31 6.22 0.32 1.49e-9 Coronary artery disease; LIHC cis rs4746818 1.000 rs6480385 chr10:70904785 A/T cg11621586 chr10:70884670 VPS26A 0.87 14.04 0.6 1.14e-35 Left atrial antero-posterior diameter; LIHC cis rs597539 0.652 rs660614 chr11:68659488 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.92 0.51 5.04e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6912958 1.000 rs6912958 chr6:88133315 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.29 -0.37 2.18e-12 Monocyte percentage of white cells; LIHC cis rs782590 0.935 rs782652 chr2:55862775 C/A cg18811423 chr2:55921094 PNPT1 0.97 15.36 0.64 7.3e-41 Metabolic syndrome; LIHC cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg11764359 chr7:65958608 NA -0.56 -5.87 -0.3 1.03e-8 Diabetic kidney disease; LIHC cis rs4555082 0.915 rs66527719 chr14:105750523 C/G cg06808227 chr14:105710500 BRF1 -0.57 -7.73 -0.39 1.21e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs4642101 0.535 rs55692304 chr3:12840057 C/T cg24848339 chr3:12840334 CAND2 0.32 6.45 0.33 3.76e-10 QRS complex (12-leadsum); LIHC cis rs4788570 0.537 rs12149254 chr16:71458851 G/A cg06353428 chr16:71660113 MARVELD3 -0.92 -8.43 -0.41 9.69e-16 Intelligence (multi-trait analysis); LIHC cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9318086 0.712 rs9510917 chr13:24442846 C/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.56 11.01 0.51 2.43e-24 Myopia (pathological); LIHC cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg06697600 chr4:7070879 GRPEL1 -0.65 -10.83 -0.51 1.04e-23 Monocyte percentage of white cells; LIHC cis rs12101261 0.536 rs2371463 chr14:81457788 G/A cg06600135 chr14:81408086 NA 0.41 7.2 0.36 3.88e-12 Graves' disease; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 23.27 0.78 1.78e-72 Prudent dietary pattern; LIHC cis rs1403694 0.515 rs710448 chr3:186452885 A/G cg12454167 chr3:186435060 KNG1 0.33 7.74 0.39 1.11e-13 Blood protein levels; LIHC cis rs1801251 1.000 rs56777991 chr2:233635388 A/C cg08000102 chr2:233561755 GIGYF2 0.76 11.52 0.53 3.62e-26 Coronary artery disease; LIHC cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg02931644 chr1:25747376 RHCE -0.37 -8.22 -0.41 4.26e-15 Erythrocyte sedimentation rate; LIHC cis rs10256972 0.869 rs1007766 chr7:1034903 G/A cg23978390 chr7:1156363 C7orf50 0.54 8.06 0.4 1.32e-14 Longevity;Endometriosis; LIHC cis rs709400 0.588 rs61996718 chr14:104048834 G/A cg26031613 chr14:104095156 KLC1 1.03 10.38 0.49 4.11e-22 Body mass index; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg14709524 chr16:89940631 TCF25 0.48 6.4 0.33 5.23e-10 Skin colour saturation; LIHC cis rs5769765 0.779 rs12170530 chr22:50318422 T/G cg26441486 chr22:50317300 CRELD2 0.39 6.59 0.34 1.65e-10 Schizophrenia; LIHC cis rs11148252 0.574 rs73186430 chr13:53232891 T/C cg12458913 chr13:53173898 NA 0.49 7.68 0.38 1.7e-13 Lewy body disease; LIHC cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg11766577 chr21:47581405 C21orf56 -0.37 -5.86 -0.3 1.1e-8 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs6499255 0.951 rs11639947 chr16:69646122 C/T cg15192750 chr16:69999425 NA 0.47 7.11 0.36 6.86e-12 IgE levels; LIHC cis rs8077889 0.703 rs231531 chr17:41946180 A/C cg26893861 chr17:41843967 DUSP3 0.67 7.18 0.36 4.27e-12 Triglycerides; LIHC cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg25072359 chr17:41440525 NA 0.39 6.05 0.31 3.75e-9 Menopause (age at onset); LIHC cis rs477692 0.905 rs489966 chr10:131422115 C/G cg19680672 chr10:131412579 MGMT 0.42 6.4 0.33 5.22e-10 Response to temozolomide; LIHC cis rs8060686 0.545 rs12444188 chr16:68282077 G/A cg09835421 chr16:68378352 PRMT7 -0.54 -6.26 -0.32 1.16e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs1499614 1.000 rs2707832 chr7:66136549 C/T cg12463550 chr7:65579703 CRCP 0.61 6.65 0.34 1.18e-10 Gout; LIHC cis rs3812831 0.635 rs6560937 chr13:114945991 C/G cg08824895 chr13:115047677 UPF3A 0.5 7.23 0.36 3.16e-12 Schizophrenia; LIHC cis rs807029 0.577 rs11190787 chr10:102758625 G/T cg17130504 chr10:102756923 LZTS2 0.55 7.59 0.38 3.15e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg07636037 chr3:49044803 WDR6 0.7 11.37 0.52 1.29e-25 Parkinson's disease; LIHC cis rs16828019 0.789 rs34216154 chr1:41670907 G/A cg20697417 chr1:41786797 NA 0.35 6.59 0.34 1.66e-10 Intelligence (multi-trait analysis); LIHC cis rs7659604 0.540 rs9998385 chr4:122676673 C/T cg19671926 chr4:122722719 EXOSC9 0.45 6.72 0.34 7.7e-11 Type 2 diabetes; LIHC cis rs1707322 1.000 rs4660905 chr1:46461587 C/T cg06784218 chr1:46089804 CCDC17 -0.36 -6.52 -0.33 2.52e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6089584 0.819 rs1467593 chr20:60601432 T/G cg06108461 chr20:60628389 TAF4 1.01 16.18 0.66 4.1e-44 Body mass index; LIHC cis rs1707322 0.650 rs4660879 chr1:46105401 C/A cg06784218 chr1:46089804 CCDC17 0.4 7.58 0.38 3.39e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs939574 1.000 rs6712442 chr2:220117333 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.94 -10.18 -0.48 1.94e-21 Platelet distribution width; LIHC cis rs6747952 0.899 rs4663856 chr2:239089624 C/A cg17459225 chr2:239074497 NA 0.36 5.81 0.3 1.47e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs734999 0.545 rs10752748 chr1:2544640 G/A cg18854424 chr1:2615690 NA 0.33 7.43 0.37 8.91e-13 Ulcerative colitis; LIHC cis rs17376456 0.877 rs28633397 chr5:93447048 A/G cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs35306767 0.623 rs72760941 chr10:1141244 A/G cg26597838 chr10:835615 NA 0.59 5.78 0.3 1.71e-8 Eosinophil percentage of granulocytes; LIHC cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg13699009 chr12:122356056 WDR66 0.59 9.46 0.46 4.95e-19 Mean corpuscular volume; LIHC cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.956 rs9988963 chr12:122991478 C/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.3 -0.37 2.02e-12 Body mass index; LIHC cis rs9858542 0.903 rs17080528 chr3:49389842 C/T cg03060546 chr3:49711283 APEH -0.47 -6.4 -0.33 5.1e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs12579753 1.000 rs17748942 chr12:82170478 G/A cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC cis rs4803468 0.934 rs2317131 chr19:41885151 C/T cg14132834 chr19:41945861 ATP5SL -0.39 -5.8 -0.3 1.51e-8 Height; LIHC cis rs7917772 0.536 rs4919667 chr10:104426011 A/G cg22532475 chr10:104410764 TRIM8 0.41 7.48 0.37 6.38e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.61 5.72 0.3 2.37e-8 Platelet count; LIHC cis rs3892630 0.588 rs12610342 chr19:33250690 C/T cg22980127 chr19:33182716 NUDT19 1.04 13.56 0.59 7.96e-34 Red blood cell traits; LIHC cis rs9378688 0.654 rs2505663 chr6:2325931 A/G cg12303981 chr6:2244766 GMDS -0.43 -6.08 -0.31 3.21e-9 Caudate nucleus volume; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12517452 chr5:52084045 ITGA1;PELO -0.4 -6.26 -0.32 1.15e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs9517313 0.897 rs4772087 chr13:99115041 A/G cg20487152 chr13:99095054 FARP1 0.41 6.91 0.35 2.33e-11 Neuroticism; LIHC cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg06634786 chr22:41940651 POLR3H -0.82 -8.85 -0.43 4.67e-17 Vitiligo; LIHC cis rs6912958 0.547 rs451089 chr6:88041859 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.36 7.06 0.36 9.18e-12 Monocyte percentage of white cells; LIHC cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg23172400 chr8:95962367 TP53INP1 -0.36 -7.88 -0.39 4.28e-14 Type 2 diabetes; LIHC cis rs2197308 0.667 rs61920838 chr12:37856814 T/C cg26384229 chr12:38710491 ALG10B -0.49 -6.91 -0.35 2.4e-11 Morning vs. evening chronotype; LIHC cis rs10089 1.000 rs62373701 chr5:127416294 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.69 0.34 9.01e-11 Ileal carcinoids; LIHC cis rs11792861 0.888 rs75543406 chr9:111816903 A/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.6 -0.34 1.55e-10 Menarche (age at onset); LIHC cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9296092 0.538 rs9461882 chr6:33520221 A/C cg13560919 chr6:33536144 NA -0.39 -6.31 -0.32 8.5e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs763121 0.853 rs2281021 chr22:39064667 T/C cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs7520050 1.000 rs785473 chr1:46516863 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.84 0.3 1.24e-8 Red blood cell count;Reticulocyte count; LIHC trans rs2727020 0.558 rs1164675 chr11:49325972 C/T cg15704280 chr7:45808275 SEPT13 0.83 14.84 0.63 8.54e-39 Coronary artery disease; LIHC cis rs6502050 0.637 rs74765203 chr17:80118223 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.98 -0.31 5.54e-9 Life satisfaction; LIHC cis rs4919087 0.748 rs11189131 chr10:99085835 G/A cg25902810 chr10:99078978 FRAT1 -0.6 -7.81 -0.39 6.9e-14 Monocyte count; LIHC cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg06238570 chr21:40685208 BRWD1 -0.59 -7.09 -0.36 7.51e-12 Cognitive function; LIHC cis rs6502050 0.835 rs62078304 chr17:80085224 G/A cg11859384 chr17:80120422 CCDC57 0.43 6.01 0.31 4.66e-9 Life satisfaction; LIHC cis rs6570726 1.000 rs951143 chr6:145932576 C/T cg23711669 chr6:146136114 FBXO30 0.5 8.54 0.42 4.58e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs10870270 0.956 rs4880405 chr10:133787021 G/A cg26149184 chr10:133730230 NA 0.5 7.83 0.39 6.05e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7666738 0.546 rs11727151 chr4:98837353 A/C cg05340658 chr4:99064831 C4orf37 0.48 6.36 0.33 6.58e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08161947 chr12:19592900 AEBP2 -0.55 -6.88 -0.35 2.86e-11 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs8192917 0.895 rs2236338 chr14:25100282 A/G cg08766149 chr14:25103301 GZMB 0.31 7.36 0.37 1.38e-12 Vitiligo; LIHC cis rs10791097 0.765 rs10894269 chr11:130722789 C/T cg12179176 chr11:130786555 SNX19 0.75 11.9 0.54 1.51e-27 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12477438 0.798 rs1349779 chr2:99645055 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.85 -11.31 -0.52 2.1e-25 Chronic sinus infection; LIHC cis rs6586163 0.872 rs1926197 chr10:90748626 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.55 -7.95 -0.39 2.72e-14 Chronic lymphocytic leukemia; LIHC cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg04025307 chr7:1156635 C7orf50 0.55 9.16 0.44 4.94e-18 Longevity;Endometriosis; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg13395646 chr4:1353034 KIAA1530 -0.44 -6.16 -0.32 2.09e-9 Longevity; LIHC cis rs2758596 1.000 rs2842875 chr1:156161794 T/C cg25208724 chr1:156163844 SLC25A44 0.75 7.57 0.38 3.5e-13 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs6988636 1.000 rs13260775 chr8:124190167 G/A cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg04546413 chr19:29218101 NA 0.56 10.25 0.48 1.1e-21 Methadone dose in opioid dependence; LIHC cis rs2404602 0.669 rs12595313 chr15:76978370 A/G cg23625390 chr15:77176239 SCAPER 0.35 5.72 0.3 2.39e-8 Blood metabolite levels; LIHC cis rs7106204 0.514 rs12291514 chr11:24360203 T/C ch.11.24196551F chr11:24239977 NA 0.71 8.61 0.42 2.75e-16 Response to Homoharringtonine (cytotoxicity); LIHC cis rs11098499 0.954 rs7681544 chr4:120411255 T/C cg09307838 chr4:120376055 NA 0.77 12.34 0.56 3.42e-29 Corneal astigmatism; LIHC cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg03517284 chr6:25882590 NA -0.6 -8.57 -0.42 3.56e-16 Blood metabolite levels; LIHC cis rs9309473 1.000 rs10496191 chr2:73673798 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.83 -0.35 3.84e-11 Metabolite levels; LIHC trans rs6489882 0.966 rs7311182 chr12:113379123 T/C cg10175203 chr3:128143634 NA 0.39 6.29 0.32 9.47e-10 Chronic lymphocytic leukemia; LIHC cis rs9359856 0.636 rs9344946 chr6:90298371 T/G cg13799429 chr6:90582589 CASP8AP2 0.59 6.53 0.33 2.43e-10 Bipolar disorder; LIHC cis rs11971779 0.680 rs4732369 chr7:139069173 C/A cg07862535 chr7:139043722 LUC7L2 0.58 9.91 0.47 1.66e-20 Diisocyanate-induced asthma; LIHC cis rs929354 0.685 rs1808217 chr7:157002741 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.1 0.55 2.67e-28 Body mass index; LIHC cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg23758822 chr17:41437982 NA 0.94 17.72 0.69 2.62e-50 Menopause (age at onset); LIHC cis rs10870270 1.000 rs4880250 chr10:133773919 G/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.83 -0.57 4.97e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10504229 0.906 rs113857287 chr8:58191683 T/C cg20607798 chr8:58055168 NA 0.49 5.91 0.3 8.09e-9 Developmental language disorder (linguistic errors); LIHC cis rs507080 0.922 rs592280 chr11:118553218 T/C cg04173919 chr11:118528438 PHLDB1 0.32 6.05 0.31 3.87e-9 Serum metabolite levels; LIHC cis rs6938 0.597 rs11856413 chr15:75199892 A/G cg14664628 chr15:75095509 CSK -0.47 -5.85 -0.3 1.14e-8 Breast cancer; LIHC cis rs2580764 0.566 rs2972072 chr2:55295370 G/T cg09592903 chr2:55203963 RTN4 0.63 11.59 0.53 2.04e-26 Mean platelet volume; LIHC cis rs1348850 0.793 rs13027299 chr2:178455501 T/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.77 11.42 0.53 8.05e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2380220 0.576 rs7751219 chr6:96018915 G/A cg04719120 chr6:96025338 MANEA 0.69 8.05 0.4 1.38e-14 Behavioural disinhibition (generation interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08651674 chr6:7108441 RREB1 0.45 6.21 0.32 1.54e-9 Pancreatic cancer; LIHC cis rs801193 0.569 rs35070132 chr7:66238083 C/T cg11764359 chr7:65958608 NA 0.74 12.42 0.56 1.7e-29 Aortic root size; LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg23990641 chr6:118823964 C6orf204;BRD7P3 0.49 5.94 0.31 7.12e-9 Diastolic blood pressure; LIHC cis rs4845570 0.920 rs10788809 chr1:151760792 A/G cg07092448 chr1:151763213 TDRKH 0.71 7.97 0.4 2.43e-14 Coronary artery disease; LIHC cis rs2257205 0.667 rs28380401 chr17:56755613 T/G cg12560992 chr17:57184187 TRIM37 0.73 7.79 0.39 8.34e-14 Pancreatic cancer; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg11070056 chr1:107600091 PRMT6 0.67 11.32 0.52 1.95e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9640161 0.750 rs4395803 chr7:150025367 A/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.54 -9.13 -0.44 6.31e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs2075371 0.863 rs12672691 chr7:133954431 C/T cg20476274 chr7:133979776 SLC35B4 0.72 9.82 0.47 3.32e-20 Mean platelet volume; LIHC cis rs34779708 0.931 rs4934720 chr10:35376800 T/C cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17384381 1.000 rs12123745 chr1:85884772 T/C cg16011679 chr1:85725395 C1orf52 0.8 8.45 0.42 8.66e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7598759 0.527 rs4973417 chr2:232349636 G/T cg19187155 chr2:232395269 NMUR1 0.57 8.29 0.41 2.58e-15 Noise-induced hearing loss; LIHC cis rs736408 0.608 rs35004449 chr3:52852897 G/T cg11645453 chr3:52864694 ITIH4 0.3 7.83 0.39 6.02e-14 Bipolar disorder; LIHC cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.26 -0.61 1.62e-36 Alzheimer's disease; LIHC trans rs6952808 0.691 rs2398709 chr7:2112548 C/T cg04565464 chr8:145669602 NFKBIL2 0.37 6.08 0.31 3.14e-9 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.508 rs10950045 chr7:66066373 T/C cg11764359 chr7:65958608 NA -0.62 -9.43 -0.45 6.37e-19 Aortic root size; LIHC cis rs2073300 1.000 rs12625999 chr20:23442085 A/G cg16736954 chr20:23401023 NAPB -0.54 -6.0 -0.31 5.13e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9611565 0.559 rs132768 chr22:42013523 C/A cg03806693 chr22:41940476 POLR3H 0.98 10.67 0.5 4.01e-23 Vitiligo; LIHC cis rs9303401 0.659 rs7216648 chr17:56790858 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs782590 0.643 rs5012561 chr2:55742032 G/C cg18811423 chr2:55921094 PNPT1 -0.54 -8.12 -0.4 8.78e-15 Metabolic syndrome; LIHC cis rs8017423 0.935 rs11628906 chr14:90738002 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -14.53 -0.62 1.42e-37 Mortality in heart failure; LIHC cis rs892961 0.932 rs7216909 chr17:75405234 A/G cg05865280 chr17:75406074 SEPT9 0.63 12.47 0.56 1.1e-29 Airflow obstruction; LIHC cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg16497277 chr3:49208875 KLHDC8B -0.52 -6.51 -0.33 2.7e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26059219 chr3:4508837 SUMF1 0.39 6.3 0.32 8.93e-10 Cognitive function; LIHC cis rs644799 0.526 rs530914 chr11:95632156 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.57 7.98 0.4 2.31e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1005277 0.579 rs1740742 chr10:38518860 C/T cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs11764590 0.694 rs3996323 chr7:2079428 G/T cg23043544 chr7:2124092 MAD1L1 -0.41 -6.6 -0.34 1.56e-10 Neuroticism; LIHC cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg16680214 chr1:154839983 KCNN3 0.33 5.88 0.3 9.53e-9 Prostate cancer; LIHC cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 9.3 0.45 1.69e-18 Platelet count; LIHC cis rs6964587 0.967 rs7801058 chr7:91784381 C/T cg17063962 chr7:91808500 NA 1.0 19.76 0.73 1.63e-58 Breast cancer; LIHC cis rs2016586 0.894 rs5755917 chr22:36099749 C/G cg26342177 chr22:36113512 APOL5 -0.4 -6.54 -0.33 2.26e-10 Body mass index; LIHC cis rs3892630 0.878 rs8112955 chr19:33191192 C/T cg22980127 chr19:33182716 NUDT19 1.02 12.43 0.56 1.56e-29 Red blood cell traits; LIHC cis rs9790314 0.875 rs462514 chr3:161092809 C/T cg03342759 chr3:160939853 NMD3 -0.67 -9.07 -0.44 9.33e-18 Morning vs. evening chronotype; LIHC cis rs6582630 0.555 rs7305352 chr12:38473800 T/C cg13010199 chr12:38710504 ALG10B 0.54 6.26 0.32 1.13e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7635838 0.654 rs164101 chr3:11281082 G/A cg00170343 chr3:11313890 ATG7 0.58 8.66 0.42 1.86e-16 HDL cholesterol; LIHC cis rs7914558 0.646 rs7897654 chr10:104662458 A/G cg15744005 chr10:104629667 AS3MT -0.33 -6.74 -0.34 6.8e-11 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs6430585 0.528 rs12474975 chr2:136702118 A/T cg07305463 chr2:136567211 LCT -0.38 -5.85 -0.3 1.18e-8 Corneal structure; LIHC cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg18225595 chr11:63971243 STIP1 0.65 8.24 0.41 3.81e-15 Mean platelet volume; LIHC cis rs10857712 0.950 rs10857711 chr10:135224059 G/A cg19623624 chr10:135278901 LOC619207 -0.44 -6.86 -0.35 3.18e-11 Systemic lupus erythematosus; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19816107 chr7:33101939 NT5C3 -0.51 -6.53 -0.33 2.37e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4319547 0.774 rs10773394 chr12:123124778 C/A cg05707623 chr12:122985044 ZCCHC8 -0.48 -6.73 -0.34 7.26e-11 Body mass index; LIHC cis rs9733 0.596 rs1336898 chr1:150665050 G/A cg13175981 chr1:150552382 MCL1 -0.44 -6.06 -0.31 3.55e-9 Tonsillectomy; LIHC cis rs79387448 0.701 rs3752659 chr2:103001598 A/G cg09003973 chr2:102972529 NA 1.1 9.73 0.47 6.4e-20 Gut microbiota (bacterial taxa); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18551892 chr11:86667149 FZD4 -0.42 -6.59 -0.34 1.64e-10 Pancreatic cancer; LIHC trans rs2744203 1.000 rs72610885 chr6:104644680 A/C cg27088726 chr16:83171155 CDH13 -0.46 -6.08 -0.31 3.14e-9 IgG glycosylation; LIHC cis rs12477438 0.765 rs17708262 chr2:99696313 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.45 -0.49 2.23e-22 Chronic sinus infection; LIHC cis rs910316 0.737 rs175077 chr14:75506875 G/A cg08847533 chr14:75593920 NEK9 -0.88 -18.17 -0.7 4.24e-52 Height; LIHC cis rs9916302 0.706 rs4287601 chr17:37513852 T/C cg07936489 chr17:37558343 FBXL20 0.85 12.19 0.55 1.26e-28 Glomerular filtration rate (creatinine); LIHC cis rs12702595 0.505 rs7811763 chr7:7266601 T/C cg04827551 chr7:7268805 C1GALT1 0.32 5.99 0.31 5.29e-9 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg18548523 chr11:67260961 PITPNM1 0.42 6.78 0.34 5.33e-11 Bipolar disorder; LIHC cis rs1443512 0.812 rs2044210 chr12:54335533 C/G cg17410650 chr12:54324560 NA -0.37 -6.56 -0.33 1.96e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg16405210 chr4:1374714 KIAA1530 -0.91 -15.34 -0.64 8.95e-41 Longevity; LIHC cis rs798554 0.959 rs798557 chr7:2758982 G/A cg19717773 chr7:2847554 GNA12 -0.4 -6.19 -0.32 1.75e-9 Height; LIHC cis rs7772486 0.790 rs2254288 chr6:146204470 G/A cg23711669 chr6:146136114 FBXO30 0.62 10.89 0.51 6.44e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs1451375 1.000 rs2329341 chr7:50620275 A/C cg14593290 chr7:50529359 DDC 0.42 6.91 0.35 2.34e-11 Malaria; LIHC cis rs919433 1.000 rs2195510 chr2:198161195 A/G cg03934865 chr2:198174659 NA -0.61 -9.93 -0.47 1.44e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs870825 0.616 rs7682677 chr4:185640717 C/G cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07355551 chr20:2489285 ZNF343 0.38 6.04 0.31 4e-9 Cognitive function; LIHC cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg08687515 chr19:58661962 ZNF329 0.98 7.56 0.38 3.82e-13 Cholesterol, total; LIHC cis rs11031096 0.655 rs12275560 chr11:4211564 T/C cg18678763 chr11:4115507 RRM1 -0.41 -5.97 -0.31 6e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7572733 0.534 rs10931794 chr2:198776140 C/T cg00792783 chr2:198669748 PLCL1 -0.46 -6.75 -0.34 6.3e-11 Dermatomyositis; LIHC cis rs722599 0.748 rs17102884 chr14:75374899 C/T cg11812906 chr14:75593930 NEK9 -0.44 -7.08 -0.36 8.15e-12 IgG glycosylation; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg02079963 chr6:160512064 IGF2R 0.41 6.13 0.31 2.41e-9 Bilirubin levels; LIHC cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg00106254 chr7:1943704 MAD1L1 0.42 6.92 0.35 2.19e-11 Bipolar disorder and schizophrenia; LIHC cis rs17685 0.816 rs11763076 chr7:75765963 C/T cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10838687 0.673 rs59567949 chr11:47300155 G/A cg26139080 chr11:47293733 MADD -0.42 -5.86 -0.3 1.08e-8 Proinsulin levels; LIHC cis rs2404602 0.647 rs116505114 chr15:77074794 T/C cg03037974 chr15:76606532 NA -0.61 -10.37 -0.49 4.39e-22 Blood metabolite levels; LIHC cis rs9549367 0.789 rs34568744 chr13:113894564 G/T cg18105134 chr13:113819100 PROZ -0.67 -11.57 -0.53 2.42e-26 Platelet distribution width; LIHC cis rs7106204 0.513 rs7131144 chr11:24249486 A/G ch.11.24196551F chr11:24239977 NA 0.73 9.02 0.44 1.37e-17 Response to Homoharringtonine (cytotoxicity); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04389422 chr12:24715564 SOX5 0.43 6.91 0.35 2.39e-11 Cognitive function; LIHC cis rs9549367 0.789 rs34448227 chr13:113884754 A/C cg00898013 chr13:113819073 PROZ -0.43 -7.46 -0.37 7.38e-13 Platelet distribution width; LIHC cis rs1008375 0.872 rs6831115 chr4:17640463 A/G cg16339924 chr4:17578868 LAP3 0.44 6.08 0.31 3.19e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg02018176 chr4:1364513 KIAA1530 0.43 5.84 0.3 1.21e-8 Longevity; LIHC cis rs992157 0.710 rs7569907 chr2:219070551 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.79 13.33 0.58 6.25e-33 Colorectal cancer; LIHC trans rs2243480 0.908 rs4718273 chr7:65216099 G/A cg10756647 chr7:56101905 PSPH -1.11 -13.6 -0.59 5.46e-34 Diabetic kidney disease; LIHC cis rs5769765 0.526 rs5770722 chr22:50253220 G/C cg02269571 chr22:50332266 NA 0.7 8.05 0.4 1.38e-14 Schizophrenia; LIHC cis rs11122272 0.735 rs2739507 chr1:231527329 T/C cg06096015 chr1:231504339 EGLN1 0.5 9.39 0.45 8.97e-19 Hemoglobin concentration; LIHC cis rs7107174 0.688 rs869202 chr11:78127914 A/G cg02023728 chr11:77925099 USP35 0.41 7.33 0.37 1.69e-12 Testicular germ cell tumor; LIHC cis rs826838 1.000 rs11183196 chr12:38685915 G/T cg26384229 chr12:38710491 ALG10B 1.07 14.89 0.63 5.24e-39 Heart rate; LIHC cis rs1215050 0.791 rs2865943 chr4:98778449 C/T cg05340658 chr4:99064831 C4orf37 0.4 5.98 0.31 5.65e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17376456 0.741 rs12374432 chr5:93481348 C/A cg25358565 chr5:93447407 FAM172A 1.1 10.07 0.48 4.48e-21 Diabetic retinopathy; LIHC cis rs9393777 0.623 rs34313099 chr6:26489607 C/T cg12826209 chr6:26865740 GUSBL1 0.66 6.91 0.35 2.44e-11 Intelligence (multi-trait analysis); LIHC trans rs7618501 1.000 rs34614773 chr3:49753003 T/G cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs12579753 1.000 rs12367791 chr12:82237278 C/T cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs11105298 0.891 rs11105313 chr12:89923376 A/T cg08166232 chr12:89918718 WDR51B;GALNT4 0.64 7.37 0.37 1.26e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs12477438 0.798 rs4851179 chr2:99568774 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.74 -11.1 -0.51 1.17e-24 Chronic sinus infection; LIHC cis rs7927771 0.832 rs11601173 chr11:47401058 A/G cg20307385 chr11:47447363 PSMC3 -0.44 -5.71 -0.3 2.45e-8 Subjective well-being; LIHC cis rs3096299 0.900 rs3114867 chr16:89428967 A/C cg00750074 chr16:89608354 SPG7 -0.37 -5.87 -0.3 1.02e-8 Multiple myeloma (IgH translocation); LIHC cis rs3806843 0.868 rs2262573 chr5:140123627 T/A cg19875535 chr5:140030758 IK -0.36 -6.01 -0.31 4.64e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs17666538 0.585 rs4448252 chr8:615597 A/G cg02524346 chr8:600233 NA 0.78 5.96 0.31 6.3e-9 IgG glycosylation; LIHC cis rs9660992 0.508 rs113817010 chr1:205104581 C/A cg21545522 chr1:205238299 TMCC2 0.31 5.86 0.3 1.11e-8 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2289583 0.597 rs12148708 chr15:75384397 G/A cg15902774 chr15:75289873 SCAMP5 0.33 6.0 0.31 4.93e-9 Systemic lupus erythematosus; LIHC cis rs6952808 0.531 rs3779003 chr7:2184902 C/T cg04267008 chr7:1944627 MAD1L1 -0.48 -7.39 -0.37 1.17e-12 Bipolar disorder and schizophrenia; LIHC cis rs8072100 0.840 rs2136751 chr17:45456093 A/G cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.85 -0.3 1.14e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs75804782 0.641 rs3769124 chr2:239349362 G/A cg01134436 chr17:81009848 B3GNTL1 0.8 6.95 0.35 1.89e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs7617480 0.549 rs9879978 chr3:48846600 T/G cg07636037 chr3:49044803 WDR6 0.76 9.31 0.45 1.64e-18 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg17372223 chr3:52568218 NT5DC2 0.35 5.76 0.3 1.93e-8 Electroencephalogram traits; LIHC cis rs12824058 0.831 rs12314111 chr12:130813663 G/T cg26677194 chr12:130822605 PIWIL1 0.51 7.15 0.36 5.29e-12 Menopause (age at onset); LIHC trans rs3780486 0.718 rs73645257 chr9:33132354 C/T cg04842962 chr6:43655489 MRPS18A 0.84 12.75 0.57 9.56e-31 IgG glycosylation; LIHC cis rs67478160 0.643 rs7147171 chr14:104264857 G/A cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs9399135 0.967 rs4896123 chr6:135295410 T/G cg22676075 chr6:135203613 NA 0.38 6.13 0.31 2.39e-9 Red blood cell count; LIHC cis rs9486719 1.000 rs12197411 chr6:97039621 G/A cg06623918 chr6:96969491 KIAA0776 -0.68 -6.85 -0.35 3.49e-11 Migraine;Coronary artery disease; LIHC cis rs7520050 0.833 rs1085242 chr1:46544224 T/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.78 0.3 1.69e-8 Red blood cell count;Reticulocyte count; LIHC cis rs10089 1.000 rs3805607 chr5:127477418 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.8 0.34 4.81e-11 Ileal carcinoids; LIHC cis rs9393692 0.905 rs989134 chr6:26336224 A/C cg13736514 chr6:26305472 NA -0.36 -6.01 -0.31 4.77e-9 Educational attainment; LIHC cis rs12971120 0.891 rs4891558 chr18:72170359 A/G cg26446133 chr18:72167187 CNDP2 -0.81 -14.7 -0.62 2.98e-38 Refractive error; LIHC cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6545883 0.868 rs7594191 chr2:61840018 A/G cg14146966 chr2:61757674 XPO1 -0.45 -7.9 -0.39 3.73e-14 Tuberculosis; LIHC trans rs1814175 0.817 rs7483795 chr11:49704930 G/A cg03929089 chr4:120376271 NA -0.91 -18.47 -0.71 2.61e-53 Height; LIHC cis rs7296418 0.922 rs1790134 chr12:123697898 T/C cg00376283 chr12:123451042 ABCB9 0.68 11.11 0.52 1.06e-24 Platelet count; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg20723414 chr7:157207071 DNAJB6 0.44 6.22 0.32 1.44e-9 Bilirubin levels; LIHC cis rs13394619 1.000 rs13394619 chr2:11727507 A/G cg07314298 chr2:11723111 GREB1 0.49 9.32 0.45 1.51e-18 Endometriosis; LIHC cis rs2304069 0.913 rs3812009 chr5:149380159 G/C cg22760475 chr5:149380129 HMGXB3;TIGD6 1.01 13.32 0.58 6.5e-33 HIV-1 control; LIHC cis rs17286411 0.787 rs1834036 chr16:71972060 G/A cg03805757 chr16:71968109 PKD1L3 0.45 6.47 0.33 3.39e-10 Blood protein levels; LIHC cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg03806693 chr22:41940476 POLR3H -1.06 -12.29 -0.55 5.36e-29 Vitiligo; LIHC cis rs5769707 0.872 rs5770604 chr22:50030672 G/A cg07959070 chr22:50026188 C22orf34 -0.32 -8.22 -0.41 4.36e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9733 0.596 rs72702523 chr1:150650425 G/T cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Tonsillectomy; LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg20302342 chr1:156215951 PAQR6 0.33 6.32 0.32 8.2e-10 Tonsillectomy; LIHC cis rs2658782 0.547 rs4753453 chr11:93041174 T/G cg15737290 chr11:93063684 CCDC67 0.47 6.17 0.32 1.88e-9 Pulmonary function decline; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.43 -0.37 8.66e-13 Lymphocyte counts; LIHC cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg06873352 chr17:61820015 STRADA 0.57 8.63 0.42 2.31e-16 Height; LIHC cis rs2404602 0.735 rs2048856 chr15:76800083 C/T cg03037974 chr15:76606532 NA -0.59 -10.05 -0.48 5.29e-21 Blood metabolite levels; LIHC cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg13271783 chr10:134563150 INPP5A -0.57 -7.29 -0.37 2.16e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs3858145 0.588 rs76854765 chr10:70037456 C/T cg04882175 chr6:131122610 NA -0.48 -6.05 -0.31 3.7e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs3096299 0.900 rs744327 chr16:89439270 C/T cg08822215 chr16:89438651 ANKRD11 -0.5 -7.94 -0.39 2.97e-14 Multiple myeloma (IgH translocation); LIHC cis rs7236492 0.683 rs59828426 chr18:77204397 T/C cg15644404 chr18:77186268 NFATC1 -0.39 -5.83 -0.3 1.29e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs13161895 1.000 rs34603792 chr5:179459287 A/G cg06664874 chr5:179499304 RNF130 0.58 7.08 0.36 8.06e-12 LDL cholesterol; LIHC cis rs8103278 0.507 rs7246377 chr19:46292259 G/A cg12641515 chr19:46296257 DMWD 0.45 6.85 0.35 3.37e-11 Coronary artery disease; LIHC cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.55 -7.84 -0.39 5.73e-14 Lymphocyte counts; LIHC cis rs881375 0.678 rs10760130 chr9:123701990 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.28 0.32 1e-9 Rheumatoid arthritis; LIHC cis rs11711311 0.712 rs3773684 chr3:113334488 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.37 6.37 0.33 6.17e-10 IgG glycosylation; LIHC cis rs939574 0.790 rs72955439 chr2:220090804 T/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.87 6.36 0.33 6.41e-10 Platelet distribution width; LIHC cis rs854765 0.647 rs2056842 chr17:18009028 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.33 6.24 0.32 1.26e-9 Total body bone mineral density; LIHC cis rs2439831 0.867 rs8039638 chr15:43634405 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.93 17.36 0.68 7.38e-49 Lung cancer in ever smokers; LIHC cis rs9790314 0.690 rs1599389 chr3:160836006 G/A cg03342759 chr3:160939853 NMD3 -0.73 -11.2 -0.52 5.37e-25 Morning vs. evening chronotype; LIHC cis rs9733 0.596 rs6686525 chr1:150635811 C/T cg17724175 chr1:150552817 MCL1 0.47 9.56 0.46 2.35e-19 Tonsillectomy; LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg10755058 chr3:40428713 ENTPD3 0.41 6.89 0.35 2.77e-11 Renal cell carcinoma; LIHC cis rs7674212 0.541 rs2720471 chr4:104023840 A/G cg16532752 chr4:104119610 CENPE -0.46 -7.26 -0.37 2.55e-12 Type 2 diabetes; LIHC cis rs8017423 0.904 rs4603489 chr14:90760607 A/G cg14092571 chr14:90743983 NA 0.44 6.98 0.35 1.53e-11 Mortality in heart failure; LIHC cis rs7937890 0.599 rs2597204 chr11:14481017 C/T cg22961513 chr11:14280813 SPON1 -0.4 -5.74 -0.3 2.14e-8 Mitochondrial DNA levels; LIHC cis rs2288073 0.930 rs7604097 chr2:24401805 G/C cg06627628 chr2:24431161 ITSN2 -0.58 -7.63 -0.38 2.32e-13 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs4423214 1.000 rs2282621 chr11:71183474 C/T cg05163923 chr11:71159392 DHCR7 0.8 12.07 0.55 3.62e-28 Vitamin D levels; LIHC cis rs79149102 0.579 rs3816261 chr15:75336173 T/A cg16226627 chr15:75307476 SCAMP5 0.54 8.93 0.43 2.59e-17 Lung cancer; LIHC cis rs1552244 0.507 rs6443274 chr3:9995288 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -8.19 -0.41 5.13e-15 Alzheimer's disease; LIHC cis rs2932538 0.922 rs6691917 chr1:113137043 G/C cg22162597 chr1:113214053 CAPZA1 0.68 10.69 0.5 3.45e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs4906332 1.000 rs8004780 chr14:103853360 A/C cg17675199 chr6:35436792 RPL10A 0.31 6.39 0.33 5.56e-10 Coronary artery disease; LIHC cis rs36051895 0.632 rs111573904 chr9:5169804 A/T cg02405213 chr9:5042618 JAK2 -0.62 -9.08 -0.44 9.14e-18 Pediatric autoimmune diseases; LIHC cis rs2120019 0.938 rs59094290 chr15:75308561 G/T cg16226627 chr15:75307476 SCAMP5 0.36 6.95 0.35 1.81e-11 Blood trace element (Zn levels); LIHC trans rs7091957 1.000 rs7091957 chr10:134439478 C/T cg13309027 chr11:47870224 NUP160 -0.45 -6.63 -0.34 1.35e-10 Gait speed in old age; LIHC cis rs17270561 1.000 rs17270561 chr6:25820439 A/C cg17691542 chr6:26056736 HIST1H1C -0.69 -7.88 -0.39 4.48e-14 Iron status biomarkers; LIHC cis rs963731 0.579 rs2060987 chr2:39282079 A/G cg04010122 chr2:39346883 SOS1 -0.66 -6.08 -0.31 3.3e-9 Corticobasal degeneration; LIHC cis rs9381040 0.537 rs9462669 chr6:41013659 C/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.41 -0.33 4.72e-10 Alzheimer's disease (late onset); LIHC cis rs2576037 0.501 rs8089938 chr18:44459497 C/T cg24750912 chr18:44543259 TCEB3CL;KATNAL2 0.34 6.23 0.32 1.34e-9 Personality dimensions; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03222257 chr8:38034392 LSM1;BAG4 -0.55 -6.42 -0.33 4.46e-10 Systolic blood pressure; LIHC cis rs7772486 0.790 rs2247666 chr6:146220409 C/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.15 -0.32 2.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10751667 0.666 rs7395823 chr11:942701 T/C ch.11.42038R chr11:967971 AP2A2 0.55 10.04 0.48 5.67e-21 Alzheimer's disease (late onset); LIHC trans rs9377619 0.541 rs9404533 chr6:104770074 C/T cg13683534 chr9:139221076 GPSM1;LOC26102 0.34 6.29 0.32 9.61e-10 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs2184586 chr6:8474182 A/G cg21535247 chr6:8435926 SLC35B3 0.62 8.19 0.41 5.17e-15 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02306730 chr19:39109456 MAP4K1;EIF3K -0.43 -6.17 -0.32 1.89e-9 Pancreatic cancer; LIHC cis rs12701220 0.553 rs7782024 chr7:1157502 G/T cg04025307 chr7:1156635 C7orf50 0.53 6.9 0.35 2.57e-11 Bronchopulmonary dysplasia; LIHC cis rs11792861 0.890 rs57387569 chr9:111920392 T/C cg05043794 chr9:111880884 C9orf5 -0.31 -6.94 -0.35 2.02e-11 Menarche (age at onset); LIHC cis rs11673344 0.832 rs8101407 chr19:37515346 A/T cg27390819 chr19:37464633 NA -0.52 -6.38 -0.33 5.73e-10 Obesity-related traits; LIHC cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg27572855 chr1:25598939 RHD 0.38 7.89 0.39 4.2e-14 Erythrocyte sedimentation rate; LIHC cis rs12908161 1.000 rs17601029 chr15:85347709 A/G cg12863693 chr15:85201151 NMB 0.44 6.27 0.32 1.11e-9 Schizophrenia; LIHC cis rs7027203 0.797 rs57882762 chr9:96580825 T/G cg13679303 chr9:96623674 NA -0.3 -6.62 -0.34 1.37e-10 DNA methylation (variation); LIHC cis rs6754311 0.731 rs12615624 chr2:136721603 A/G cg07305463 chr2:136567211 LCT -0.37 -7.14 -0.36 5.78e-12 Mosquito bite size; LIHC cis rs17001868 0.568 rs9611328 chr22:40791972 C/T cg07138101 chr22:40742427 ADSL 0.55 6.62 0.34 1.4e-10 Mammographic density (dense area); LIHC cis rs2050392 1.000 rs2183176 chr10:30698544 C/T cg25182066 chr10:30743637 MAP3K8 0.43 6.93 0.35 2.06e-11 Inflammatory bowel disease; LIHC cis rs8108269 0.911 rs10415769 chr19:46158643 G/T cg13320842 chr19:46175254 GIPR 0.41 7.7 0.38 1.5e-13 Type 2 diabetes; LIHC cis rs981946 0.928 rs13193394 chr6:3369046 C/T cg18842474 chr6:3356384 SLC22A23 0.36 5.72 0.3 2.34e-8 Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN); LIHC cis rs17826219 0.714 rs11650821 chr17:28968150 T/C cg13385521 chr17:29058706 SUZ12P 0.66 6.21 0.32 1.55e-9 Body mass index; LIHC cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg17554472 chr22:41940697 POLR3H 0.56 6.06 0.31 3.53e-9 Vitiligo; LIHC cis rs10078 0.515 rs1053299 chr5:470760 G/A cg08916839 chr5:415575 AHRR 0.6 12.71 0.57 1.45e-30 Fat distribution (HIV); LIHC cis rs8044995 0.563 rs56220628 chr16:68384837 G/A cg05110241 chr16:68378359 PRMT7 -0.84 -9.56 -0.46 2.45e-19 Schizophrenia; LIHC cis rs4699052 0.963 rs2085978 chr4:104193614 A/G cg16532752 chr4:104119610 CENPE -0.39 -6.07 -0.31 3.34e-9 Testicular germ cell tumor; LIHC cis rs9902453 0.934 rs11080120 chr17:28507021 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.18 0.44 4.1e-18 Coffee consumption (cups per day); LIHC cis rs35365539 1 rs35365539 chr3:49794347 A/AC cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Blood protein levels; LIHC cis rs7116495 1.000 rs4945434 chr11:71759087 A/G cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs35110281 0.805 rs2838330 chr21:45023876 T/A cg04455712 chr21:45112962 RRP1B 0.45 7.57 0.38 3.4e-13 Mean corpuscular volume; LIHC cis rs34172651 0.917 rs8049667 chr16:24773524 G/A cg04756594 chr16:24857601 SLC5A11 0.48 7.62 0.38 2.46e-13 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg19318889 chr4:1322082 MAEA 0.41 5.91 0.3 8.37e-9 Obesity-related traits; LIHC cis rs8062405 1.000 rs62036616 chr16:28826307 A/G cg07451762 chr16:28383216 NA 0.36 6.66 0.34 1.07e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg13271783 chr10:134563150 INPP5A -0.58 -7.24 -0.36 3.01e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2412488 0.850 rs11133266 chr4:54234371 G/T cg22241045 chr4:54363911 LNX1 -0.42 -6.4 -0.33 5.2e-10 DNA methylation (variation); LIHC cis rs7772486 0.790 rs9497431 chr6:146248177 T/C cg05347473 chr6:146136440 FBXO30 -0.37 -5.86 -0.3 1.07e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs8083850 0.698 rs12956187 chr18:50869695 A/G cg24270629 chr18:50823537 DCC 0.52 7.87 0.39 4.7e-14 Intelligence (multi-trait analysis); LIHC cis rs72843506 0.586 rs16960554 chr17:19869798 A/G cg12065943 chr17:19881925 AKAP10 -0.39 -6.58 -0.34 1.78e-10 Schizophrenia; LIHC cis rs3784262 0.669 rs4646594 chr15:58302386 C/A cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.73 -0.3 2.21e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21068152 chr12:120740453 SIRT4 0.46 7.19 0.36 4.04e-12 Cognitive function; LIHC cis rs11690935 0.550 rs6746701 chr2:172869255 G/A cg13550731 chr2:172543902 DYNC1I2 0.47 7.03 0.36 1.1e-11 Schizophrenia; LIHC cis rs919433 0.750 rs788010 chr2:198230949 T/C cg10820045 chr2:198174542 NA 0.56 8.88 0.43 3.78e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2439831 0.867 rs12324572 chr15:43636200 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.93 17.36 0.68 7.38e-49 Lung cancer in ever smokers; LIHC cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg27170947 chr2:26402098 FAM59B 0.66 8.24 0.41 3.72e-15 Gut microbiome composition (summer); LIHC cis rs769267 0.930 rs10402451 chr19:19608537 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.2 0.32 1.58e-9 Tonsillectomy; LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs6717918 0.672 rs2853359 chr2:233118874 C/G ch.2.233013039R chr2:233304795 NA 0.59 6.17 0.32 1.91e-9 Height; LIHC cis rs6545883 0.894 rs2593633 chr2:61571513 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.38 -0.37 1.21e-12 Tuberculosis; LIHC cis rs1506636 1.000 rs767637 chr7:123321978 C/A cg03229431 chr7:123269106 ASB15 -0.6 -12.14 -0.55 1.85e-28 Plateletcrit;Platelet count; LIHC cis rs908922 0.676 rs4845441 chr1:152485421 C/T cg20991723 chr1:152506922 NA 0.55 9.44 0.45 6.15e-19 Hair morphology; LIHC cis rs4819052 0.851 rs10470247 chr21:46659018 T/C cg11663144 chr21:46675770 NA -0.33 -6.16 -0.32 2.03e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7107174 1.000 rs2512538 chr11:77972461 T/G cg02023728 chr11:77925099 USP35 0.5 9.51 0.46 3.41e-19 Testicular germ cell tumor; LIHC cis rs72781680 0.611 rs72797818 chr2:24351107 G/A cg06627628 chr2:24431161 ITSN2 -0.62 -7.31 -0.37 1.88e-12 Lymphocyte counts; LIHC cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg20607798 chr8:58055168 NA 0.6 7.16 0.36 4.89e-12 Developmental language disorder (linguistic errors); LIHC cis rs116248771 0.739 rs73156415 chr3:158342695 C/A cg16708174 chr3:158430962 RARRES1 0.48 6.41 0.33 4.83e-10 diarrhoeal disease at age 2; LIHC trans rs2270221 0.723 rs11763013 chr7:31909596 C/T cg06873401 chr5:77792105 LHFPL2 0.49 6.05 0.31 3.72e-9 Endometriosis; LIHC cis rs10540 0.558 rs12806062 chr11:501429 G/A cg26566283 chr11:622021 MUPCDH -0.81 -6.14 -0.31 2.35e-9 Body mass index; LIHC cis rs9457247 0.555 rs2247325 chr6:167369992 A/G cg12798992 chr6:167411361 FGFR1OP -0.43 -6.28 -0.32 1.01e-9 Crohn's disease; LIHC trans rs1899546 1.000 rs11027852 chr11:24399181 G/T cg20999565 chr14:68265668 ZFYVE26 -0.34 -6.07 -0.31 3.45e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs4474465 0.920 rs9804428 chr11:78158948 G/A cg02023728 chr11:77925099 USP35 0.34 6.11 0.31 2.67e-9 Alzheimer's disease (survival time); LIHC cis rs9296092 0.538 rs62405943 chr6:33517359 A/G cg13560919 chr6:33536144 NA -0.38 -6.36 -0.33 6.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs736801 0.504 rs2070721 chr5:131825842 T/G cg21138405 chr5:131827807 IRF1 0.31 7.55 0.38 4e-13 Breast cancer;Mosquito bite size; LIHC cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg18252515 chr7:66147081 NA -1.27 -16.34 -0.66 9.2e-45 Diabetic kidney disease; LIHC cis rs6598955 0.670 rs10902734 chr1:26617923 G/T cg00852783 chr1:26633632 UBXN11 -0.51 -8.52 -0.42 5.07e-16 Obesity-related traits; LIHC cis rs1865760 0.566 rs2032449 chr6:26026599 G/C cg18357526 chr6:26021779 HIST1H4A 0.46 6.78 0.34 5.36e-11 Height; LIHC trans rs11098499 0.663 rs28369503 chr4:120238925 G/A cg25214090 chr10:38739885 LOC399744 0.53 8.57 0.42 3.6e-16 Corneal astigmatism; LIHC cis rs7617773 0.780 rs11714944 chr3:48366971 C/A cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg16132339 chr22:24313637 DDTL;DDT 0.73 13.95 0.6 2.44e-35 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs11098499 0.954 rs12507964 chr4:120413061 T/A cg25214090 chr10:38739885 LOC399744 0.57 9.44 0.45 6.19e-19 Corneal astigmatism; LIHC cis rs9381040 0.701 rs6933231 chr6:41163700 T/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.37 -6.35 -0.32 6.92e-10 Alzheimer's disease (late onset); LIHC cis rs6463523 0.864 rs73047957 chr7:759373 A/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.97 16.13 0.66 6.11e-44 Subjective well-being; LIHC trans rs11098499 0.820 rs28535956 chr4:120536858 C/T cg25214090 chr10:38739885 LOC399744 -0.55 -8.91 -0.43 3.04e-17 Corneal astigmatism; LIHC cis rs2153535 0.546 rs9378559 chr6:8539058 A/T cg21535247 chr6:8435926 SLC35B3 0.64 8.22 0.41 4.21e-15 Motion sickness; LIHC cis rs7639513 0.767 rs7648488 chr3:12708946 T/C cg23032965 chr3:12705835 RAF1 0.65 7.85 0.39 5.27e-14 Itch intensity from mosquito bite; LIHC cis rs13191362 0.938 rs28360532 chr6:162997477 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.92 0.3 7.85e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7107174 1.000 rs7127187 chr11:77995188 G/A cg02023728 chr11:77925099 USP35 0.5 9.62 0.46 1.56e-19 Testicular germ cell tumor; LIHC cis rs7520050 0.872 rs1707308 chr1:46604315 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.44 6.78 0.34 5.28e-11 Red blood cell count;Reticulocyte count; LIHC cis rs10489202 0.908 rs6692861 chr1:168079553 G/C cg17859187 chr1:168147929 TIPRL 0.51 6.53 0.33 2.33e-10 Schizophrenia; LIHC cis rs1728785 1.000 rs1615609 chr16:68596401 C/A cg02972257 chr16:68554789 NA -0.55 -6.21 -0.32 1.55e-9 Ulcerative colitis; LIHC cis rs1728785 1.000 rs4783657 chr16:68586322 G/T cg02972257 chr16:68554789 NA -0.57 -6.41 -0.33 4.83e-10 Ulcerative colitis; LIHC cis rs3540 0.574 rs2526000 chr15:90962626 C/T cg22089800 chr15:90895588 ZNF774 0.56 7.74 0.39 1.17e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs10751667 0.666 rs11246358 chr11:967349 G/A cg06064525 chr11:970664 AP2A2 -0.56 -14.91 -0.63 4.53e-39 Alzheimer's disease (late onset); LIHC cis rs10504229 0.679 rs12675340 chr8:58035501 T/A cg02290350 chr8:58132656 NA 0.31 7.18 0.36 4.24e-12 Developmental language disorder (linguistic errors); LIHC cis rs9290065 0.686 rs1839021 chr3:160623669 T/G cg03342759 chr3:160939853 NMD3 0.53 7.04 0.36 1.07e-11 Kawasaki disease; LIHC cis rs611744 0.647 rs11774904 chr8:109273435 G/A cg21045802 chr8:109455806 TTC35 0.58 10.23 0.48 1.32e-21 Dupuytren's disease; LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.9 -0.3 8.51e-9 Total body bone mineral density; LIHC trans rs1814175 0.645 rs28549248 chr11:50042740 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs9388451 0.531 rs9401850 chr6:126151000 T/G cg05901451 chr6:126070800 HEY2 -0.45 -7.68 -0.38 1.67e-13 Brugada syndrome; LIHC cis rs3859192 0.537 rs12309 chr17:38175462 C/T cg17467752 chr17:38218738 THRA -0.5 -8.57 -0.42 3.74e-16 White blood cell count; LIHC cis rs992157 0.798 rs7557709 chr2:219167529 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.77 12.28 0.55 5.89e-29 Colorectal cancer; LIHC cis rs9419702 0.568 rs10782366 chr10:133557866 G/A cg04492858 chr10:133558786 NA 0.47 7.16 0.36 4.98e-12 Survival in rectal cancer; LIHC cis rs12477438 0.501 rs1133977 chr2:99741984 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -9.94 -0.47 1.32e-20 Chronic sinus infection; LIHC cis rs2637266 0.935 rs7909808 chr10:78392318 A/G cg18941641 chr10:78392320 NA 0.29 6.26 0.32 1.14e-9 Pulmonary function; LIHC cis rs7707921 0.752 rs2406909 chr5:81276087 T/C cg15871215 chr5:81402204 ATG10 0.66 7.16 0.36 5.09e-12 Breast cancer; LIHC trans rs5756813 0.754 rs5750495 chr22:38179120 T/A cg19894588 chr14:64061835 NA 0.61 8.55 0.42 4.12e-16 Optic cup area;Vertical cup-disc ratio; LIHC cis rs4975616 0.869 rs467095 chr5:1336221 T/C cg06550200 chr5:1325588 CLPTM1L -0.69 -10.96 -0.51 3.76e-24 Lung cancer; LIHC cis rs5769765 0.542 rs1033666 chr22:50252783 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.58 5.81 0.3 1.44e-8 Schizophrenia; LIHC trans rs561341 1.000 rs113115092 chr17:30284164 G/A cg20587970 chr11:113659929 NA -1.38 -11.72 -0.54 6.87e-27 Hip circumference adjusted for BMI; LIHC cis rs546131 0.642 rs473848 chr11:34851977 A/C cg11058730 chr11:34937778 PDHX;APIP 0.64 9.38 0.45 9.45e-19 Lung disease severity in cystic fibrosis; LIHC cis rs477692 1.000 rs531572 chr10:131427569 A/G cg05714579 chr10:131428358 MGMT -0.47 -7.89 -0.39 4.1e-14 Response to temozolomide; LIHC cis rs7762018 1.000 rs6459657 chr6:170136454 A/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.52 6.34 0.32 7.4e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs67981189 0.634 rs221898 chr14:71605516 A/G cg15816911 chr14:71606274 NA 0.42 6.75 0.34 6.23e-11 Schizophrenia; LIHC cis rs903552 0.673 rs4965878 chr15:102009589 C/T cg19295451 chr15:102010161 PCSK6 -0.55 -7.63 -0.38 2.34e-13 Diabetic kidney disease; LIHC cis rs2836950 0.565 rs8134214 chr21:40542367 A/C cg17971929 chr21:40555470 PSMG1 -0.4 -6.15 -0.32 2.12e-9 Menarche (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg04882175 chr6:131122610 NA 0.54 6.81 0.35 4.33e-11 Hepatitis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05016131 chr16:29606629 NA -0.53 -6.32 -0.32 8.08e-10 Systolic blood pressure; LIHC trans rs654384 0.898 rs13242365 chr7:4175025 G/T cg26675336 chr15:86133334 AKAP13 0.3 6.16 0.32 2.08e-9 Positive affect; LIHC cis rs763121 0.853 rs2072798 chr22:39148483 G/A cg06544989 chr22:39130855 UNC84B 0.38 5.97 0.31 6.05e-9 Menopause (age at onset); LIHC trans rs79976124 0.842 rs1548154 chr6:66624910 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.63 6.81 0.35 4.29e-11 Type 2 diabetes; LIHC trans rs4843747 0.636 rs4075597 chr16:88107590 C/A cg26811252 chr16:29126840 RRN3P2 0.41 6.62 0.34 1.39e-10 Menopause (age at onset); LIHC cis rs1046896 1.000 rs9909940 chr17:80689036 C/T cg00809820 chr17:80708513 TBCD;FN3K 0.35 6.03 0.31 4.31e-9 Glycated hemoglobin levels; LIHC cis rs4474465 0.688 rs10501429 chr11:78279790 T/G cg27205649 chr11:78285834 NARS2 0.48 7.4 0.37 1.08e-12 Alzheimer's disease (survival time); LIHC cis rs6442522 0.643 rs7620149 chr3:15500896 A/G cg16303742 chr3:15540471 COLQ -0.42 -7.05 -0.36 9.81e-12 Uric acid levels; LIHC cis rs2991971 0.782 rs10789463 chr1:45927848 C/A cg05343316 chr1:45956843 TESK2 0.46 6.89 0.35 2.73e-11 High light scatter reticulocyte count; LIHC trans rs208520 0.690 rs12192851 chr6:66705862 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.74 8.52 0.42 5.1e-16 Exhaled nitric oxide output; LIHC cis rs7131987 0.650 rs10843382 chr12:29451721 G/A cg12903224 chr12:29470962 FAR2 -0.42 -6.81 -0.35 4.31e-11 QT interval; LIHC cis rs67478160 0.643 rs4906369 chr14:104242458 T/C cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.7 -0.38 1.45e-13 Schizophrenia; LIHC cis rs2976388 0.609 rs2572908 chr8:143802636 A/G cg13446199 chr8:143762866 PSCA -0.2 -5.85 -0.3 1.12e-8 Urinary tract infection frequency; LIHC cis rs10751667 0.600 rs6597948 chr11:1005308 C/T ch.11.42038R chr11:967971 AP2A2 0.6 11.22 0.52 4.3e-25 Alzheimer's disease (late onset); LIHC cis rs4561483 0.832 rs171656 chr16:11953167 C/T cg08843971 chr16:11963173 GSPT1 -0.43 -8.54 -0.42 4.39e-16 Testicular germ cell tumor; LIHC cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg08859206 chr1:53392774 SCP2 0.36 5.98 0.31 5.76e-9 Monocyte count; LIHC cis rs28829049 0.536 rs2073105 chr1:19549864 T/C cg13387374 chr1:19411106 UBR4 0.39 5.76 0.3 1.9e-8 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs13217239 0.646 rs10456351 chr6:26986792 C/T cg18867708 chr6:26865862 GUSBL1 0.52 8.1 0.4 9.8e-15 Schizophrenia; LIHC trans rs2243480 1.000 rs316332 chr7:65604299 A/G cg10756647 chr7:56101905 PSPH 1.09 13.36 0.59 4.74e-33 Diabetic kidney disease; LIHC cis rs12540874 0.698 rs3807566 chr7:50564204 G/T cg18232548 chr7:50535776 DDC -0.4 -6.01 -0.31 4.84e-9 Systemic sclerosis; LIHC cis rs425277 0.958 rs626479 chr1:2110260 A/G cg24578937 chr1:2090814 PRKCZ -0.5 -9.02 -0.44 1.33e-17 Height; LIHC cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg10360323 chr17:41437877 NA 0.4 5.98 0.31 5.76e-9 Menopause (age at onset); LIHC cis rs2239547 0.562 rs6794389 chr3:53096394 A/G cg11645453 chr3:52864694 ITIH4 0.28 7.06 0.36 9.32e-12 Schizophrenia; LIHC cis rs7617773 0.963 rs6800730 chr3:48174210 C/T cg11946769 chr3:48343235 NME6 0.53 7.24 0.36 3.07e-12 Coronary artery disease; LIHC cis rs8032158 1.000 rs8029247 chr15:56273446 C/T cg24530489 chr15:56299380 NA -0.42 -5.94 -0.31 7.21e-9 Keloid; LIHC cis rs921968 0.541 rs647990 chr2:219441428 T/C cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.63e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2073300 0.609 rs3827086 chr20:23357331 C/T cg16736954 chr20:23401023 NAPB 0.7 8.14 0.4 7.4e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9916302 0.847 rs7218670 chr17:37500424 G/A cg00129232 chr17:37814104 STARD3 0.38 6.15 0.32 2.21e-9 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.863 rs10019674 chr4:120443489 C/T cg09307838 chr4:120376055 NA -0.75 -11.49 -0.53 4.64e-26 Corneal astigmatism; LIHC cis rs9368481 0.645 rs10456350 chr6:26975581 A/C cg12292205 chr6:26970375 C6orf41 0.47 8.05 0.4 1.41e-14 Autism spectrum disorder or schizophrenia; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.67 0.38 1.8e-13 Prudent dietary pattern; LIHC cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.27 -0.37 2.41e-12 Bipolar disorder; LIHC trans rs66573146 0.634 rs56097119 chr4:7018692 C/G cg07817883 chr1:32538562 TMEM39B 0.93 7.29 0.37 2.21e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs4975616 0.869 rs421284 chr5:1325590 T/C cg07493874 chr5:1342172 CLPTM1L -0.66 -10.74 -0.5 2.3e-23 Lung cancer; LIHC trans rs980000 1.000 rs980000 chr15:60900963 C/T cg19429466 chr4:87515395 PTPN13 -0.79 -6.08 -0.31 3.18e-9 Menarche (age at onset); LIHC cis rs1707322 1.000 rs4660318 chr1:46334876 A/G cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2073499 1.000 rs6776145 chr3:50316119 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.82 -11.46 -0.53 5.93e-26 Schizophrenia; LIHC cis rs4975616 0.804 rs457130 chr5:1336178 A/T cg07493874 chr5:1342172 CLPTM1L -0.66 -10.75 -0.5 2.02e-23 Lung cancer; LIHC trans rs7618501 0.633 rs2252833 chr3:50004209 C/T cg21659725 chr3:3221576 CRBN 0.67 10.74 0.5 2.24e-23 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg12463550 chr7:65579703 CRCP 0.67 7.03 0.36 1.15e-11 Diabetic kidney disease; LIHC cis rs929354 0.742 rs2107863 chr7:156963731 T/C cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg09145019 chr1:17972199 ARHGEF10L 0.56 6.23 0.32 1.37e-9 Mean platelet volume; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.57 0.62 9.41e-38 Prudent dietary pattern; LIHC cis rs116095464 0.558 rs6875291 chr5:264192 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs7264396 0.563 rs2425132 chr20:34338390 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.59 -8.45 -0.42 8.7e-16 Total cholesterol levels; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg12419862 chr22:24373484 LOC391322 -0.68 -10.39 -0.49 3.8e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs62012628 0.527 rs12438008 chr15:79084680 C/T cg04896959 chr15:78267971 NA -0.52 -10.38 -0.49 4.01e-22 Diastolic blood pressure; LIHC trans rs57221529 0.766 rs12522303 chr5:555564 A/C cg25482853 chr8:67687455 SGK3 0.67 6.67 0.34 1.03e-10 Lung disease severity in cystic fibrosis; LIHC cis rs7116495 0.609 rs4387373 chr11:71774908 A/G cg26138937 chr11:71823887 C11orf51 -1.32 -10.43 -0.49 2.71e-22 Severe influenza A (H1N1) infection; LIHC cis rs3733606 0.503 rs11731274 chr4:6891455 T/G cg05012661 chr4:6891264 NA 0.39 6.26 0.32 1.12e-9 Platelet count; LIHC cis rs3020736 0.500 rs4147640 chr22:42485292 T/C cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs2637030 0.559 rs372135 chr5:52944948 T/C cg06476337 chr5:52856530 NDUFS4 0.43 6.82 0.35 4.25e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC trans rs877282 0.947 rs7904978 chr10:768078 C/T cg22713356 chr15:30763199 NA 1.38 12.35 0.56 3.16e-29 Uric acid levels; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg17158414 chr2:27665306 KRTCAP3 0.44 5.98 0.31 5.71e-9 Total body bone mineral density; LIHC cis rs17270561 0.887 rs9358870 chr6:25719210 T/C cg17691542 chr6:26056736 HIST1H1C 0.64 7.1 0.36 7.25e-12 Iron status biomarkers; LIHC cis rs7903847 0.642 rs11189177 chr10:99141663 C/T cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs77741769 0.571 rs3861797 chr12:121255334 T/C cg02419362 chr12:121203948 SPPL3 0.34 5.93 0.31 7.36e-9 Mean corpuscular volume; LIHC cis rs1198430 0.639 rs16860685 chr1:23766644 A/G cg13183780 chr1:23809682 ASAP3 -0.37 -6.47 -0.33 3.31e-10 Total cholesterol levels; LIHC cis rs2274273 0.870 rs11625001 chr14:55758160 T/C cg01864836 chr14:55583639 NA -0.37 -6.55 -0.33 2.15e-10 Protein biomarker; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15231902 chr12:56618064 OBFC2B 0.44 6.3 0.32 9.14e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs916888 0.773 rs199439 chr17:44793503 A/G cg07870213 chr5:140052090 DND1 1.04 10.68 0.5 3.61e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6952808 0.771 rs4719336 chr7:1916397 T/C cg02951883 chr7:2050386 MAD1L1 -0.53 -7.81 -0.39 7.19e-14 Bipolar disorder and schizophrenia; LIHC cis rs7192380 0.651 rs920191 chr16:69689120 G/A cg15192750 chr16:69999425 NA 0.36 5.72 0.3 2.28e-8 Sjögren's syndrome; LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg22963979 chr7:1858916 MAD1L1 -0.45 -7.53 -0.38 4.58e-13 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg07677032 chr17:61819896 STRADA 0.43 6.17 0.32 1.98e-9 Prudent dietary pattern; LIHC cis rs875971 0.545 rs73376394 chr7:65637681 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.38 7.68 0.38 1.64e-13 Aortic root size; LIHC cis rs11122272 0.701 rs2883799 chr1:231531166 C/G cg06096015 chr1:231504339 EGLN1 0.5 9.21 0.45 3.3e-18 Hemoglobin concentration; LIHC cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg06634786 chr22:41940651 POLR3H -0.8 -8.87 -0.43 4.24e-17 Vitiligo; LIHC cis rs910316 0.712 rs175037 chr14:75465038 T/C cg08847533 chr14:75593920 NEK9 -0.87 -17.87 -0.69 6.79e-51 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21321768 chr18:19176371 ESCO1 0.28 6.06 0.31 3.64e-9 Cognitive function; LIHC cis rs2153535 0.580 rs9406158 chr6:8464152 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC trans rs66573146 1.000 rs55672215 chr4:6970529 T/C cg07817883 chr1:32538562 TMEM39B 1.24 9.74 0.47 6.14e-20 Granulocyte percentage of myeloid white cells; LIHC cis rs4919694 1.000 rs12258551 chr10:104767892 C/G cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg06873352 chr17:61820015 STRADA 0.75 13.72 0.6 1.95e-34 Prudent dietary pattern; LIHC cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg17971929 chr21:40555470 PSMG1 0.84 10.02 0.48 6.79e-21 Cognitive function; LIHC cis rs66573146 0.831 rs56300156 chr4:6990813 G/C cg00086871 chr4:6988644 TBC1D14 0.88 5.96 0.31 6.31e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7267979 1.000 rs11100 chr20:25281184 G/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs1062177 0.950 rs892005 chr5:151180621 A/G cg00977110 chr5:151150581 G3BP1 0.54 6.9 0.35 2.52e-11 Preschool internalizing problems; LIHC cis rs6500602 0.893 rs6500598 chr16:4470964 G/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.08 0.31 3.15e-9 Schizophrenia; LIHC cis rs12291225 0.679 rs11605531 chr11:14291594 A/G cg19336497 chr11:14380999 RRAS2 -0.64 -12.76 -0.57 9.25e-31 Sense of smell; LIHC cis rs7000551 0.700 rs2469761 chr8:22367274 A/G cg12081754 chr8:22256438 SLC39A14 0.44 7.37 0.37 1.3e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2012796 1.000 rs8009171 chr14:81820060 G/A cg02996355 chr14:81879375 NA 0.45 6.79 0.34 5.04e-11 Night sleep phenotypes; LIHC cis rs2637266 1.000 rs34483246 chr10:78342790 G/A cg18941641 chr10:78392320 NA 0.3 6.41 0.33 4.93e-10 Pulmonary function; LIHC cis rs7715806 0.500 rs17649332 chr5:75003878 T/C cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs8002861 0.901 rs9525867 chr13:44463557 G/A cg17145862 chr1:211918768 LPGAT1 0.67 13.31 0.58 7.42e-33 Leprosy; LIHC cis rs7927592 0.913 rs12363722 chr11:68236291 A/C cg20283391 chr11:68216788 NA -0.52 -7.79 -0.39 7.98e-14 Total body bone mineral density; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg11494091 chr17:61959527 GH2 0.44 8.07 0.4 1.23e-14 Prudent dietary pattern; LIHC cis rs921968 0.643 rs833083 chr2:219336959 A/T cg02985541 chr2:219472218 PLCD4 -0.47 -8.79 -0.43 7.21e-17 Mean corpuscular hemoglobin concentration; LIHC cis rs3741151 1.000 rs7941454 chr11:73085336 C/T cg17517138 chr11:73019481 ARHGEF17 0.77 6.0 0.31 4.9e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg16434002 chr17:42200994 HDAC5 0.54 7.82 0.39 6.67e-14 Total body bone mineral density; LIHC cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg21724239 chr8:58056113 NA 0.44 5.93 0.31 7.47e-9 Developmental language disorder (linguistic errors); LIHC cis rs11190604 1.000 rs4919470 chr10:102298920 C/T cg07080220 chr10:102295463 HIF1AN 0.56 8.01 0.4 1.85e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7264396 0.676 rs6060729 chr20:34557004 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC trans rs7613875 0.600 rs2624848 chr3:50165101 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.45 -6.75 -0.34 6.41e-11 Body mass index; LIHC cis rs6976053 0.518 rs314358 chr7:100410657 A/G cg01903971 chr7:100434983 NA -0.39 -6.35 -0.32 6.79e-10 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC cis rs9303401 0.625 rs66508449 chr17:56691034 T/C cg25039879 chr17:56429692 SUPT4H1 0.77 8.77 0.43 8.65e-17 Cognitive test performance; LIHC cis rs10791097 0.967 rs10894268 chr11:130717153 C/T cg12179176 chr11:130786555 SNX19 0.61 9.4 0.45 8.23e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9611565 0.546 rs5758431 chr22:42109917 A/G cg06634786 chr22:41940651 POLR3H 0.59 6.39 0.33 5.54e-10 Vitiligo; LIHC cis rs2439831 0.867 rs2614811 chr15:43913487 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.66 9.22 0.45 3.12e-18 Lung cancer in ever smokers; LIHC cis rs10504229 0.610 rs7840469 chr8:58146992 C/T cg02290350 chr8:58132656 NA 0.42 9.08 0.44 8.67e-18 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs9326778 0.520 rs11956367 chr5:108818903 G/A cg17395555 chr5:108820864 NA -0.34 -5.86 -0.3 1.11e-8 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs10078 0.571 rs890977 chr5:476910 T/C cg24955955 chr5:415729 AHRR 0.6 11.31 0.52 2.02e-25 Fat distribution (HIV); LIHC cis rs7000551 0.606 rs7844699 chr8:22248920 G/T cg12081754 chr8:22256438 SLC39A14 -0.9 -16.3 -0.66 1.33e-44 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2439831 1.000 rs471229 chr15:43733994 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.77 0.6 1.2e-34 Lung cancer in ever smokers; LIHC cis rs2153535 0.580 rs4960413 chr6:8438466 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.67 0.53 1.03e-26 Motion sickness; LIHC cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg18357526 chr6:26021779 HIST1H4A 0.6 8.49 0.42 6.45e-16 Blood metabolite levels; LIHC cis rs16866061 1.000 rs1568750 chr2:225342597 A/T cg12698349 chr2:225449008 CUL3 0.73 12.54 0.56 6.38e-30 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07277818 chr5:137774639 REEP2 0.41 6.06 0.31 3.51e-9 Lung function (FEV1/FVC); LIHC cis rs9916302 0.851 rs6503518 chr17:37660469 A/G cg00129232 chr17:37814104 STARD3 -0.42 -6.81 -0.35 4.45e-11 Glomerular filtration rate (creatinine); LIHC cis rs1005277 0.579 rs1780121 chr10:38529437 C/A cg25427524 chr10:38739819 LOC399744 -0.72 -14.15 -0.61 4.37e-36 Extrinsic epigenetic age acceleration; LIHC trans rs9914544 0.545 rs3826380 chr17:18793225 A/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.46 -0.33 3.65e-10 Educational attainment (years of education); LIHC cis rs10791097 0.690 rs12286234 chr11:130730528 T/C cg14779329 chr11:130786720 SNX19 0.39 5.95 0.31 6.72e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.68 0.34 9.49e-11 Electroencephalogram traits; LIHC cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg06634786 chr22:41940651 POLR3H 0.83 9.16 0.44 4.85e-18 Vitiligo; LIHC cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.27e-12 Bipolar disorder; LIHC cis rs11864453 0.647 rs3764314 chr16:72127078 T/C cg01557791 chr16:72042693 DHODH -0.42 -6.97 -0.35 1.63e-11 Fibrinogen levels; LIHC cis rs9733 0.596 rs11204704 chr1:150671630 T/C cg18016565 chr1:150552671 MCL1 0.58 11.5 0.53 4.36e-26 Tonsillectomy; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg11494091 chr17:61959527 GH2 -0.45 -8.26 -0.41 3.19e-15 Prudent dietary pattern; LIHC cis rs16958440 0.867 rs12326465 chr18:44678645 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC trans rs2071426 0.959 rs11572139 chr10:96808886 A/G cg04948438 chr10:99301906 UBTD1 -0.36 -6.12 -0.31 2.52e-9 Blood metabolite levels; LIHC cis rs9911578 0.935 rs302873 chr17:56769481 C/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.64 -0.42 2.17e-16 Intelligence (multi-trait analysis); LIHC cis rs4561483 0.624 rs2288547 chr16:11935436 C/T cg08843971 chr16:11963173 GSPT1 0.41 7.06 0.36 9.31e-12 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg11764359 chr7:65958608 NA 0.58 6.02 0.31 4.5e-9 Diabetic kidney disease; LIHC cis rs722599 0.683 rs8022046 chr14:75278302 G/A cg11812906 chr14:75593930 NEK9 0.43 6.51 0.33 2.63e-10 IgG glycosylation; LIHC cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg24209194 chr3:40518798 ZNF619 -0.64 -9.73 -0.47 6.37e-20 Renal cell carcinoma; LIHC cis rs2991971 0.933 rs12568144 chr1:45965307 G/A cg05343316 chr1:45956843 TESK2 -0.43 -6.4 -0.33 5.08e-10 High light scatter reticulocyte count; LIHC trans rs3960554 0.569 rs11973658 chr7:75882026 A/C cg19862616 chr7:65841803 NCRNA00174 0.64 9.98 0.47 9.69e-21 Eotaxin levels; LIHC cis rs28830936 0.510 rs7174099 chr15:42099059 A/G cg17847044 chr15:42102381 MAPKBP1 -0.48 -11.73 -0.54 6.14e-27 Diastolic blood pressure; LIHC cis rs10426930 0.738 rs2613757 chr19:5062405 T/C cg18473234 chr19:5097819 KDM4B -0.43 -5.73 -0.3 2.26e-8 Monocyte percentage of white cells; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg10266188 chr1:32645867 TXLNA -0.41 -6.06 -0.31 3.59e-9 Bipolar disorder; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg12394426 chr11:64009745 FKBP2 -0.41 -6.34 -0.32 7.28e-10 Triglycerides; LIHC cis rs8180040 0.764 rs11718795 chr3:47218727 G/A cg16586182 chr3:47516702 SCAP -0.51 -9.17 -0.44 4.43e-18 Colorectal cancer; LIHC cis rs763121 0.853 rs1013338 chr22:38974154 C/A cg14440974 chr22:39074834 NA -0.35 -5.89 -0.3 9.1e-9 Menopause (age at onset); LIHC cis rs1451375 0.652 rs7803903 chr7:50625945 C/T cg14593290 chr7:50529359 DDC 0.49 7.86 0.39 5.03e-14 Malaria; LIHC cis rs3809566 1.000 rs4775612 chr15:63332157 T/C cg12160578 chr15:63334699 TPM1 -0.6 -8.6 -0.42 2.96e-16 Platelet count; LIHC cis rs7829975 0.593 rs2921077 chr8:8304502 C/T cg08975724 chr8:8085496 FLJ10661 0.43 6.87 0.35 3.06e-11 Mood instability; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg26338869 chr17:61819248 STRADA 0.58 8.88 0.43 3.75e-17 Prudent dietary pattern; LIHC cis rs1707322 1.000 rs10890353 chr1:46298383 G/T cg06784218 chr1:46089804 CCDC17 0.35 6.35 0.32 6.71e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16163324 chr1:46712932 RAD54L 0.44 6.37 0.33 6.09e-10 Lung function (FEV1/FVC); LIHC cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg20607798 chr8:58055168 NA 0.71 8.55 0.42 4.1e-16 Developmental language disorder (linguistic errors); LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg07021052 chr2:20871279 NA -0.41 -7.42 -0.37 9.48e-13 Abdominal aortic aneurysm; LIHC cis rs2153535 0.580 rs2143355 chr6:8517856 T/A cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.52e-16 Motion sickness; LIHC cis rs9399135 0.967 rs1023179 chr6:135343829 T/A cg24558204 chr6:135376177 HBS1L 0.42 6.86 0.35 3.16e-11 Red blood cell count; LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs5769707 0.632 rs5770601 chr22:50021903 A/G cg01652190 chr22:50026171 C22orf34 -0.35 -7.7 -0.38 1.48e-13 Monocyte count;Monocyte percentage of white cells; LIHC trans rs1814175 0.616 rs4881723 chr11:49788566 G/T cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.48e-59 Height; LIHC cis rs240764 0.578 rs12215909 chr6:101227598 T/C cg09795085 chr6:101329169 ASCC3 -0.48 -7.16 -0.36 5e-12 Neuroticism; LIHC cis rs992157 0.798 rs10193383 chr2:219157692 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.78 12.51 0.56 8.22e-30 Colorectal cancer; LIHC cis rs7412746 0.611 rs12410869 chr1:150856153 G/T cg18016565 chr1:150552671 MCL1 0.5 9.52 0.46 3.37e-19 Melanoma; LIHC cis rs2257205 0.667 rs7208872 chr17:56777649 A/G cg12560992 chr17:57184187 TRIM37 0.72 7.93 0.39 3.17e-14 Pancreatic cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01958230 chr17:40428024 STAT5B -0.53 -6.12 -0.31 2.61e-9 Systolic blood pressure; LIHC cis rs801193 1.000 rs2659915 chr7:66153101 A/G cg11764359 chr7:65958608 NA 0.69 10.4 0.49 3.53e-22 Aortic root size; LIHC trans rs11039798 0.557 rs683180 chr11:48463949 A/G cg15704280 chr7:45808275 SEPT13 -0.58 -6.38 -0.33 5.79e-10 Axial length; LIHC cis rs10916814 0.588 rs10799640 chr1:20896411 T/C cg24502330 chr1:20914028 CDA -0.31 -6.76 -0.34 6.01e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs8180040 0.764 rs12630534 chr3:47001043 T/C cg16586182 chr3:47516702 SCAP -0.46 -8.26 -0.41 3.13e-15 Colorectal cancer; LIHC cis rs6831352 0.801 rs2602897 chr4:100046293 A/T cg12011299 chr4:100065546 ADH4 0.63 10.64 0.5 4.89e-23 Alcohol dependence; LIHC cis rs11098499 0.644 rs10012252 chr4:120559139 T/C cg09307838 chr4:120376055 NA 0.67 10.25 0.48 1.15e-21 Corneal astigmatism; LIHC cis rs10193935 0.901 rs2118889 chr2:42451683 G/T cg27598129 chr2:42591480 NA -0.67 -10.15 -0.48 2.38e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs6691722 0.503 rs7546875 chr1:24703667 T/C cg18323236 chr1:24743029 NIPAL3 0.38 7.08 0.36 8.34e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs6840360 0.571 rs11736116 chr4:152531816 A/G cg22705602 chr4:152727874 NA -0.32 -6.37 -0.33 5.95e-10 Intelligence (multi-trait analysis); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg18120998 chr12:113376286 OAS3 -0.43 -6.12 -0.31 2.54e-9 Alopecia areata; LIHC cis rs7336332 0.511 rs7998978 chr13:27999457 T/C cg01674679 chr13:27998804 GTF3A -0.49 -7.61 -0.38 2.73e-13 Weight; LIHC cis rs4927850 0.918 rs4361313 chr3:195752260 A/G cg01181863 chr3:195395398 SDHAP2 -0.52 -6.69 -0.34 9.34e-11 Pancreatic cancer; LIHC cis rs929843 1 rs929843 chr16:70045748 A/C cg09409435 chr16:70099608 PDXDC2 0.89 8.16 0.4 6.36e-15 Menarche (age at onset); LIHC cis rs12621445 1 rs12621445 chr2:24154964 C/T cg08917208 chr2:24149416 ATAD2B 0.94 8.07 0.4 1.17e-14 Immature fraction of reticulocytes; LIHC cis rs921968 0.540 rs7582329 chr2:219620909 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1003719 0.788 rs3787782 chr21:38462909 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.44e-28 Eye color traits; LIHC cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg18306943 chr3:40428807 ENTPD3 0.42 7.38 0.37 1.24e-12 Renal cell carcinoma; LIHC trans rs4704846 0.660 rs246878 chr5:156556674 C/T cg02632742 chr2:60187357 NA -0.6 -6.05 -0.31 3.83e-9 Blood protein levels; LIHC cis rs9355610 0.727 rs2247315 chr6:167370211 A/C cg23791538 chr6:167370224 RNASET2 0.79 14.76 0.62 1.74e-38 Graves' disease; LIHC cis rs4803468 1.000 rs3213861 chr19:41919944 A/C cg09537434 chr19:41945824 ATP5SL -1.02 -21.69 -0.76 3.18e-66 Height; LIHC cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg23982607 chr1:1823379 GNB1 -0.69 -13.57 -0.59 7.32e-34 Body mass index; LIHC cis rs11671005 0.693 rs34230465 chr19:58943576 C/G cg25952890 chr19:58913133 NA 0.7 7.64 0.38 2.23e-13 Mean platelet volume; LIHC cis rs10206020 0.921 rs9678719 chr2:1549628 A/G cg01028140 chr2:1542097 TPO -0.45 -7.16 -0.36 4.98e-12 IgG glycosylation; LIHC cis rs2797160 0.515 rs4897149 chr6:125980018 G/T cg05901451 chr6:126070800 HEY2 0.47 8.34 0.41 1.82e-15 Endometrial cancer; LIHC cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.3 -6.12 -0.31 2.59e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs17102423 0.731 rs10143198 chr14:65555471 C/T cg16583315 chr14:65563665 MAX -0.4 -8.17 -0.4 6.07e-15 Obesity-related traits; LIHC cis rs4689388 0.926 rs5018648 chr4:6292818 C/G cg00701064 chr4:6280414 WFS1 -0.5 -8.17 -0.4 6.06e-15 Type 2 diabetes and other traits;Type 2 diabetes; LIHC cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg00149659 chr3:10157352 C3orf10 0.68 6.94 0.35 1.98e-11 Alzheimer's disease; LIHC cis rs66573146 0.572 rs73199995 chr4:6955801 G/C cg15105060 chr4:7024189 TBC1D14 -0.68 -6.1 -0.31 2.88e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.09 -0.31 3.09e-9 Total body bone mineral density; LIHC cis rs1448094 0.527 rs1900700 chr12:86232166 C/T cg02569458 chr12:86230093 RASSF9 0.49 6.53 0.33 2.37e-10 Major depressive disorder; LIHC cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg11987759 chr7:65425863 GUSB 0.38 6.0 0.31 5.09e-9 Aortic root size; LIHC cis rs919433 0.963 rs4850786 chr2:198178608 A/G cg10820045 chr2:198174542 NA 0.55 9.25 0.45 2.43e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11212260 0.655 rs11212237 chr11:107310213 T/A cg25435332 chr11:107328525 CWF19L2 0.84 8.08 0.4 1.15e-14 IgG glycosylation; LIHC cis rs924607 1.000 rs924607 chr5:610093 C/T cg04221910 chr5:616842 CEP72 -0.41 -7.42 -0.37 9.5e-13 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs7020830 0.931 rs1388978 chr9:37144062 G/T cg14294708 chr9:37120828 ZCCHC7 1.07 22.78 0.78 1.5e-70 Schizophrenia; LIHC cis rs2274273 0.837 rs8008119 chr14:55831228 T/C cg01864836 chr14:55583639 NA -0.37 -6.65 -0.34 1.13e-10 Protein biomarker; LIHC cis rs826838 0.967 rs73096706 chr12:38860563 G/A cg26384229 chr12:38710491 ALG10B 0.95 12.62 0.56 3.2e-30 Heart rate; LIHC cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.47 6.15 0.32 2.19e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs507080 0.769 rs645637 chr11:118505090 G/A cg04173919 chr11:118528438 PHLDB1 0.32 5.87 0.3 1.06e-8 Serum metabolite levels; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.03 0.8 2.65e-79 Prudent dietary pattern; LIHC cis rs7772486 0.686 rs9390357 chr6:146129347 A/G cg23711669 chr6:146136114 FBXO30 0.65 11.78 0.54 4.06e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7095607 0.579 rs6480308 chr10:69952953 T/C cg18986048 chr10:69913749 MYPN 0.38 5.73 0.3 2.25e-8 Lung function (FVC); LIHC cis rs13424612 1.000 rs13424612 chr2:240900121 C/T cg01812947 chr2:240904978 NDUFA10 0.37 5.73 0.3 2.21e-8 Odorant perception (isobutyraldehyde); LIHC cis rs3815700 1.000 rs8113165 chr19:33096316 C/T cg02997394 chr19:33096574 ANKRD27 0.72 9.53 0.46 2.91e-19 Eosinophilic esophagitis; LIHC cis rs921968 0.565 rs7595901 chr2:219606931 A/G cg02985541 chr2:219472218 PLCD4 -0.36 -6.34 -0.32 7.39e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7528419 1.000 rs646776 chr1:109818530 C/T cg06804625 chr1:109812012 CELSR2 -0.4 -5.78 -0.3 1.71e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs933688 1.000 rs6866191 chr5:90746852 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.89 16.26 0.66 1.87e-44 Smoking behavior; LIHC cis rs6815814 0.950 rs11722889 chr4:38810975 C/T cg06935464 chr4:38784597 TLR10 0.46 7.19 0.36 4.1e-12 Breast cancer; LIHC trans rs3749237 0.964 rs11717463 chr3:49808981 C/T cg21659725 chr3:3221576 CRBN 0.8 12.5 0.56 8.57e-30 Resting heart rate; LIHC trans rs2749592 1.000 rs2749592 chr10:38258842 A/C cg17830980 chr10:43048298 ZNF37B -0.41 -7.36 -0.37 1.41e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg08392591 chr16:89556376 ANKRD11 0.52 8.08 0.4 1.13e-14 Multiple myeloma (IgH translocation); LIHC cis rs10106298 0.846 rs2436940 chr8:103678521 A/C cg10187029 chr8:103597600 NA 0.47 6.42 0.33 4.55e-10 Schizophrenia; LIHC cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg05368731 chr17:41323189 NBR1 0.72 12.47 0.56 1.08e-29 Menopause (age at onset); LIHC cis rs1577917 0.655 rs9444354 chr6:86291935 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.44 8.24 0.41 3.79e-15 Response to antipsychotic treatment; LIHC cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg08280861 chr8:58055591 NA 0.54 6.28 0.32 1.05e-9 Developmental language disorder (linguistic errors); LIHC trans rs2840044 0.554 rs225267 chr17:33964228 T/C cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Response to radiotherapy in cancer (late toxicity); LIHC cis rs17685 0.753 rs4728586 chr7:75802869 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.36 -0.33 6.6e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1843834 0.539 rs2047135 chr2:225427302 G/C cg22455342 chr2:225449267 CUL3 0.61 8.81 0.43 6.51e-17 IgE levels in asthmatics (D.p. specific); LIHC cis rs3806843 0.900 rs2337984 chr5:140136811 G/A cg26395211 chr5:140044315 WDR55 0.4 5.87 0.3 1.05e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1551570 0.766 rs55752217 chr19:10218434 C/T cg16327482 chr19:10226339 EIF3G 0.48 8.37 0.41 1.53e-15 Narcolepsy; LIHC cis rs35110281 0.805 rs162402 chr21:44963418 G/C cg21573476 chr21:45109991 RRP1B -0.52 -9.69 -0.46 8.64e-20 Mean corpuscular volume; LIHC cis rs9916302 0.861 rs4795376 chr17:37669043 T/C cg00129232 chr17:37814104 STARD3 -0.41 -6.57 -0.33 1.93e-10 Glomerular filtration rate (creatinine); LIHC trans rs75804782 0.581 rs3191996 chr2:239344412 A/G cg01134436 chr17:81009848 B3GNTL1 -0.74 -6.76 -0.34 5.94e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg14257396 chr1:107603778 NA -0.37 -6.17 -0.32 1.98e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs597539 0.652 rs579136 chr11:68637476 C/G cg04772025 chr11:68637568 NA 0.46 6.22 0.32 1.44e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg00750074 chr16:89608354 SPG7 -0.41 -6.22 -0.32 1.48e-9 Multiple myeloma (IgH translocation); LIHC cis rs6500602 0.727 rs6500607 chr16:4503631 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.46 6.66 0.34 1.12e-10 Schizophrenia; LIHC cis rs7945705 0.869 rs4909952 chr11:8963946 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.39 6.6 0.34 1.61e-10 Hemoglobin concentration; LIHC trans rs208520 0.874 rs208470 chr6:66916402 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.7 -7.76 -0.39 9.73e-14 Exhaled nitric oxide output; LIHC cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg22442454 chr1:209979470 IRF6 0.39 5.92 0.3 7.76e-9 Cleft lip with or without cleft palate; LIHC cis rs7829975 0.593 rs2921061 chr8:8317615 A/T cg15556689 chr8:8085844 FLJ10661 0.53 7.86 0.39 5.04e-14 Mood instability; LIHC cis rs1775715 0.737 rs1419171 chr10:32214831 C/A cg14930904 chr10:32216787 ARHGAP12 0.37 6.54 0.33 2.26e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs4728302 0.583 rs1424583 chr7:133159583 T/G cg10665199 chr7:133106180 EXOC4 0.52 8.72 0.43 1.24e-16 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs5758511 0.680 rs1033459 chr22:42619067 A/G cg20195005 chr22:42527684 CYP2D6 0.31 5.96 0.31 6.14e-9 Birth weight; LIHC cis rs2180341 0.711 rs4371861 chr6:127568447 G/T cg24812749 chr6:127587940 RNF146 0.5 7.71 0.38 1.38e-13 Breast cancer; LIHC cis rs4742903 0.967 rs6479215 chr9:106885243 A/G cg14250997 chr9:106856677 SMC2 -0.42 -7.48 -0.38 6.23e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs9372253 0.934 rs9320327 chr6:110715194 T/A cg00083206 chr6:110721305 DDO -0.33 -6.68 -0.34 9.68e-11 Platelet distribution width; LIHC cis rs1866706 1.000 rs1866704 chr11:12866938 T/C cg25843174 chr11:12811716 TEAD1 -0.33 -6.95 -0.35 1.86e-11 Intelligence (multi-trait analysis); LIHC cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg11301795 chr4:187892539 NA 0.26 6.69 0.34 9.18e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1008375 0.966 rs7675735 chr4:17587137 T/A cg02297831 chr4:17616191 MED28 0.48 7.33 0.37 1.68e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7027203 0.828 rs3996239 chr9:96611290 T/A cg13679303 chr9:96623674 NA -0.29 -6.4 -0.33 5.17e-10 DNA methylation (variation); LIHC cis rs8192917 1.000 rs6573911 chr14:25100933 A/G cg08766149 chr14:25103301 GZMB -0.35 -8.13 -0.4 8.11e-15 Vitiligo; LIHC cis rs4908768 0.501 rs910581 chr1:8529524 T/C cg20416874 chr1:8611966 RERE -0.66 -13.71 -0.6 2.11e-34 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00774050 chr4:73935472 COX18 -0.46 -6.32 -0.32 8.26e-10 Pancreatic cancer; LIHC cis rs1707322 0.721 rs10430123 chr1:46221440 T/C cg03146154 chr1:46216737 IPP 0.6 10.28 0.49 9.16e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs910316 0.687 rs11627442 chr14:75669649 A/G cg11812906 chr14:75593930 NEK9 -0.65 -11.39 -0.52 1.09e-25 Height; LIHC cis rs826838 0.654 rs7977738 chr12:38722460 G/A cg26384229 chr12:38710491 ALG10B 0.59 8.17 0.4 6.16e-15 Heart rate; LIHC cis rs6024905 0.595 rs2022499 chr20:36966531 G/T cg07053727 chr20:36965646 BPI 0.59 10.94 0.51 4.28e-24 Bipolar disorder and schizophrenia; LIHC cis rs9640161 0.617 rs73170169 chr7:150008036 G/A cg10018233 chr7:150070692 REPIN1 0.43 6.52 0.33 2.56e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg13047869 chr3:10149882 C3orf24 0.52 5.92 0.3 7.9e-9 Alzheimer's disease; LIHC cis rs17685 0.697 rs28689051 chr7:75763624 G/A cg04610667 chr7:75704037 NA -0.34 -6.21 -0.32 1.55e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24371536 chr6:79943342 HMGN3 0.46 6.16 0.32 2.03e-9 Pancreatic cancer; LIHC cis rs9583531 0.600 rs6492303 chr13:111356800 G/A cg24331049 chr13:111365604 ING1 0.77 13.03 0.58 8.91e-32 Coronary artery disease; LIHC cis rs11792861 0.816 rs3818932 chr9:111664178 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.62 0.42 2.58e-16 Menarche (age at onset); LIHC cis rs12472274 0.646 rs35468889 chr2:239090959 G/A cg17459225 chr2:239074497 NA 0.72 11.31 0.52 2.07e-25 Phospholipid levels (plasma); LIHC trans rs3758911 0.796 rs59525924 chr11:107210012 C/T cg21068293 chr15:74496576 STRA6 0.26 6.27 0.32 1.08e-9 Coronary artery disease; LIHC cis rs6459804 0.967 rs10233396 chr7:157512290 C/T cg05731713 chr7:157510257 PTPRN2 0.23 6.48 0.33 3.16e-10 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg24846343 chr22:24311635 DDTL -0.63 -10.7 -0.5 3e-23 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs910316 0.789 rs4899552 chr14:75667921 C/A cg11812906 chr14:75593930 NEK9 -0.69 -12.82 -0.57 5.58e-31 Height; LIHC cis rs208520 0.779 rs208446 chr6:66903515 T/C cg07460842 chr6:66804631 NA -0.7 -7.58 -0.38 3.24e-13 Exhaled nitric oxide output; LIHC trans rs4714291 0.832 rs9471244 chr6:40092331 A/G cg02267698 chr19:7991119 CTXN1 0.4 6.85 0.35 3.53e-11 Strep throat; LIHC cis rs2836950 0.527 rs2836948 chr21:40599677 T/C cg06238570 chr21:40685208 BRWD1 -0.43 -6.81 -0.35 4.53e-11 Menarche (age at onset); LIHC cis rs7772486 0.701 rs697056 chr6:146003897 C/T cg13319975 chr6:146136371 FBXO30 0.39 6.39 0.33 5.42e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.862 rs11769079 chr7:65842128 G/A cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs11792861 0.962 rs3750454 chr9:111801325 C/G cg13535736 chr9:111863775 C9orf5 0.42 6.39 0.33 5.28e-10 Menarche (age at onset); LIHC cis rs2845885 1.000 rs2845885 chr11:63869062 A/G cg24431193 chr11:63883947 FLRT1;MACROD1 0.59 7.79 0.39 8.37e-14 Body mass index; LIHC cis rs7296418 0.961 rs1790122 chr12:123606739 G/A cg00376283 chr12:123451042 ABCB9 0.74 12.98 0.57 1.37e-31 Platelet count; LIHC trans rs2727020 0.930 rs1164686 chr11:49291822 C/T cg18944383 chr4:111397179 ENPEP -0.28 -6.49 -0.33 3.02e-10 Coronary artery disease; LIHC cis rs1023500 0.596 rs133350 chr22:42429049 A/G cg05082376 chr22:42548792 NA -0.4 -5.76 -0.3 1.84e-8 Schizophrenia; LIHC cis rs7264396 0.635 rs6060710 chr20:34536055 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.33 -0.49 6.13e-22 Total cholesterol levels; LIHC cis rs9858542 0.953 rs11922013 chr3:49458355 G/C cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6499255 1.000 rs8045682 chr16:69786092 C/A cg15192750 chr16:69999425 NA 0.46 7.04 0.36 1.09e-11 IgE levels; LIHC cis rs7927592 0.913 rs11228276 chr11:68307525 A/G cg01657329 chr11:68192670 LRP5 -0.47 -6.07 -0.31 3.46e-9 Total body bone mineral density; LIHC trans rs8113308 0.810 rs8108525 chr19:52444136 G/T cg14959425 chr7:20447707 ITGB8 -0.48 -6.15 -0.32 2.22e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs15676 0.947 rs2280842 chr9:131585808 C/G cg00228799 chr9:131580591 ENDOG 0.47 7.15 0.36 5.46e-12 Blood metabolite levels; LIHC cis rs67311347 1.000 rs9874006 chr3:40471596 G/A cg09455208 chr3:40491958 NA 0.36 7.4 0.37 1.09e-12 Renal cell carcinoma; LIHC cis rs11628318 0.660 rs8009475 chr14:103058608 A/G cg01864069 chr14:103024347 NA -0.48 -7.48 -0.37 6.48e-13 Platelet count; LIHC cis rs888194 0.738 rs7956536 chr12:109980516 A/G cg05360138 chr12:110035743 NA -0.4 -5.75 -0.3 2.03e-8 Neuroticism; LIHC cis rs9814567 1.000 rs7428326 chr3:134251184 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3015497 0.586 rs12587842 chr14:51092562 A/G cg09863266 chr14:51125203 SAV1 -0.39 -6.17 -0.32 1.88e-9 Mean platelet volume; LIHC cis rs11229555 0.645 rs34350060 chr11:58184902 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs8067354 0.507 rs72840511 chr17:57806011 G/T cg13753209 chr17:57696993 CLTC 0.77 12.29 0.55 5.3e-29 Hemoglobin concentration; LIHC cis rs66887589 0.775 rs6843229 chr4:120424087 T/C cg09307838 chr4:120376055 NA 0.45 6.85 0.35 3.49e-11 Diastolic blood pressure; LIHC cis rs7100689 0.646 rs6585967 chr10:82139791 A/G cg01528321 chr10:82214614 TSPAN14 -0.85 -12.4 -0.56 1.99e-29 Post bronchodilator FEV1; LIHC cis rs3814244 0.515 rs2906856 chr12:68390201 T/C cg15249341 chr12:68405565 NA 0.34 7.07 0.36 8.6e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs7613875 0.600 rs2247510 chr3:50126215 A/C cg21467203 chr3:49911342 NA -0.52 -9.56 -0.46 2.44e-19 Body mass index; LIHC cis rs7267979 0.528 rs6076366 chr20:25564626 G/T cg24626310 chr20:25276739 ABHD12;PYGB -0.44 -6.02 -0.31 4.47e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs1552244 0.554 rs3846169 chr3:9997054 A/G cg21531657 chr3:10005747 TMEM111 -0.39 -5.87 -0.3 1.03e-8 Alzheimer's disease; LIHC cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg12016809 chr21:47604291 C21orf56 0.42 6.21 0.32 1.5e-9 Testicular germ cell tumor; LIHC cis rs12477438 1.000 rs11897712 chr2:99735697 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.69 -7.7 -0.38 1.48e-13 Chronic sinus infection; LIHC cis rs2836974 0.666 rs4818015 chr21:40675493 A/C cg06238570 chr21:40685208 BRWD1 0.55 8.86 0.43 4.42e-17 Cognitive function; LIHC cis rs35110281 0.563 rs162371 chr21:44931489 G/T cg04455712 chr21:45112962 RRP1B 0.45 7.61 0.38 2.68e-13 Mean corpuscular volume; LIHC trans rs1814175 0.616 rs10769644 chr11:49987676 C/A cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs10751667 0.666 rs7395823 chr11:942701 T/C cg06064525 chr11:970664 AP2A2 -0.55 -14.97 -0.63 2.48e-39 Alzheimer's disease (late onset); LIHC cis rs7192750 0.538 rs11075911 chr16:71988505 T/C cg06353428 chr16:71660113 MARVELD3 0.78 9.05 0.44 1.1e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg24250549 chr1:154909240 PMVK 0.69 11.0 0.51 2.63e-24 Prostate cancer; LIHC cis rs3981351 0.797 rs34394259 chr10:115441082 A/G cg24846397 chr10:115438155 CASP7 -0.45 -6.98 -0.35 1.58e-11 Obesity-related traits; LIHC cis rs12464559 0.579 rs1523181 chr2:152679462 T/C cg01189475 chr2:152685088 ARL5A 0.64 7.54 0.38 4.29e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.47 0.46 4.59e-19 Electroencephalogram traits; LIHC cis rs921968 0.648 rs538483 chr2:219458656 T/C cg17980119 chr2:219472607 PLCD4 0.34 5.88 0.3 9.92e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs2777491 1.000 rs2777491 chr15:41735710 T/G cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.29 -0.45 1.85e-18 Ulcerative colitis; LIHC cis rs4129767 0.647 rs1976703 chr17:76401328 C/T cg02836325 chr17:76403955 PGS1 0.34 6.71 0.34 8.09e-11 HDL cholesterol; LIHC cis rs35110281 0.693 rs4819290 chr21:45122713 C/T cg04455712 chr21:45112962 RRP1B 0.48 8.48 0.42 6.83e-16 Mean corpuscular volume; LIHC cis rs2806561 0.929 rs2903545 chr1:23541108 C/T cg19743168 chr1:23544995 NA -0.39 -7.18 -0.36 4.37e-12 Height; LIHC cis rs12701220 0.522 rs1881116 chr7:1053958 C/T cg00990874 chr7:1149470 C7orf50 -0.53 -7.86 -0.39 4.96e-14 Bronchopulmonary dysplasia; LIHC cis rs2834188 1.000 rs2843994 chr21:34706870 G/A cg14352951 chr21:34696688 IFNAR1 0.51 6.72 0.34 7.54e-11 Narcolepsy; LIHC cis rs7833986 0.501 rs2953909 chr8:56968200 T/C cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.02e-16 Height; LIHC cis rs6089584 0.507 rs6061990 chr20:60628429 T/G cg13770153 chr20:60521292 NA -0.3 -5.74 -0.3 2.03e-8 Body mass index; LIHC cis rs12928939 0.815 rs7185575 chr16:71672569 A/G cg03805757 chr16:71968109 PKD1L3 -0.6 -6.78 -0.34 5.24e-11 Post bronchodilator FEV1; LIHC cis rs4917300 0.626 rs1388796 chr8:143096437 A/G cg25363559 chr8:143086065 NA -0.27 -8.25 -0.41 3.55e-15 Amyotrophic lateral sclerosis; LIHC cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg13047869 chr3:10149882 C3orf24 0.54 6.49 0.33 2.99e-10 Alzheimer's disease; LIHC cis rs919433 0.963 rs10166569 chr2:198183439 G/A cg03934865 chr2:198174659 NA -0.57 -9.09 -0.44 8e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7552404 0.731 rs11588578 chr1:76400539 T/G cg03433033 chr1:76189801 ACADM 0.6 7.27 0.37 2.54e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs5769765 1.000 rs5770755 chr22:50280136 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.05 0.44 1.12e-17 Schizophrenia; LIHC cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg23283495 chr1:209979779 IRF6 0.45 7.12 0.36 6.27e-12 Cleft lip with or without cleft palate; LIHC cis rs7659604 0.540 rs4240264 chr4:122683818 A/G cg19671926 chr4:122722719 EXOSC9 0.53 8.11 0.4 9.07e-15 Type 2 diabetes; LIHC cis rs929354 0.772 rs1182365 chr7:157017255 A/T cg05182265 chr7:156933206 UBE3C 0.33 6.3 0.32 8.96e-10 Body mass index; LIHC trans rs2243480 1.000 rs1723269 chr7:65472786 C/G cg10756647 chr7:56101905 PSPH 1.08 13.28 0.58 9.41e-33 Diabetic kidney disease; LIHC cis rs8027181 0.839 rs11072385 chr15:73020839 A/G cg25632853 chr15:73088954 NA 0.36 5.99 0.31 5.27e-9 Triglyceride levels; LIHC cis rs924607 0.966 rs1709554 chr5:637443 A/G cg04476341 chr5:669733 TPPP 0.38 8.69 0.43 1.55e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6502050 0.835 rs9900128 chr17:80087920 A/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.68 -11.34 -0.52 1.66e-25 Height; LIHC cis rs597539 0.652 rs611046 chr11:68631704 A/G cg06028808 chr11:68637592 NA 0.43 5.84 0.3 1.2e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg12310025 chr6:25882481 NA 0.57 7.8 0.39 7.43e-14 Blood metabolite levels; LIHC cis rs459482 0.576 rs461448 chr21:42800923 C/A cg14166395 chr21:42792516 MX1 0.44 6.13 0.31 2.45e-9 IgG glycosylation; LIHC cis rs11583043 1.000 rs7541397 chr1:101322866 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.66 -7.84 -0.39 5.8e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg06558623 chr16:89946397 TCF25 0.84 12.35 0.56 3.22e-29 Skin colour saturation; LIHC cis rs7911264 0.628 rs6583833 chr10:94409800 C/T cg00519463 chr10:94352821 KIF11 -0.46 -6.44 -0.33 3.99e-10 Inflammatory bowel disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25976004 chr4:56815073 CEP135 -0.5 -6.48 -0.33 3.29e-10 Systolic blood pressure; LIHC cis rs9300255 0.506 rs11057251 chr12:123791227 A/G cg05973401 chr12:123451056 ABCB9 -0.42 -6.42 -0.33 4.61e-10 Neutrophil percentage of white cells; LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg02951883 chr7:2050386 MAD1L1 -0.52 -7.86 -0.39 4.96e-14 Bipolar disorder and schizophrenia; LIHC cis rs1003719 0.680 rs767998 chr21:38525652 T/G cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.08 -0.51 1.43e-24 Eye color traits; LIHC cis rs2153535 0.580 rs7741456 chr6:8452424 G/A cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC cis rs34245846 0.704 rs11264280 chr1:154862952 C/T cg24250549 chr1:154909240 PMVK -0.68 -9.08 -0.44 8.6e-18 Atrial fibrillation; LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg14828511 chr1:107599125 PRMT6 0.4 5.72 0.3 2.35e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs727505 1.000 rs722560 chr7:124488035 T/C cg23710748 chr7:124431027 NA -0.33 -5.82 -0.3 1.37e-8 Lewy body disease; LIHC cis rs10464366 0.544 rs6952466 chr7:39155032 A/T cg15212455 chr7:39170539 POU6F2 0.48 8.74 0.43 1.05e-16 IgG glycosylation; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg21941105 chr19:10491405 TYK2 -0.47 -6.64 -0.34 1.24e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs2075165 1.000 rs2075165 chr1:156215899 G/A cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.85 0.3 1.14e-8 Tonsillectomy; LIHC cis rs17021463 0.872 rs10856909 chr4:95268748 C/G cg11021082 chr4:95130006 SMARCAD1 0.43 7.68 0.38 1.64e-13 Testicular germ cell tumor; LIHC cis rs611744 0.967 rs639059 chr8:109236119 G/A cg18478394 chr8:109455254 TTC35 0.38 6.67 0.34 1.04e-10 Dupuytren's disease; LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.9 7.74 0.39 1.11e-13 Platelet count; LIHC cis rs250677 0.687 rs250672 chr5:148446110 A/G cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs1707322 0.717 rs3014245 chr1:46086913 C/T cg03146154 chr1:46216737 IPP -0.56 -9.5 -0.46 3.68e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2303759 0.709 rs10411679 chr19:49826480 A/T cg22307029 chr19:49891270 CCDC155 0.56 8.62 0.42 2.52e-16 Multiple sclerosis; LIHC cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg08888203 chr3:10149979 C3orf24 0.56 6.48 0.33 3.23e-10 Alzheimer's disease; LIHC cis rs7945718 0.870 rs10831903 chr11:12758660 C/T cg25843174 chr11:12811716 TEAD1 0.35 7.93 0.39 3.24e-14 Educational attainment (years of education); LIHC cis rs11864453 0.612 rs12708925 chr16:72122706 A/T cg16558253 chr16:72132732 DHX38 -0.44 -7.2 -0.36 3.94e-12 Fibrinogen levels; LIHC trans rs12780046 0.656 rs1539396 chr10:100824035 C/G cg05980083 chr9:112191166 PTPN3 -0.5 -6.53 -0.33 2.38e-10 Non-glioblastoma glioma; LIHC cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg20607798 chr8:58055168 NA 0.6 7.26 0.37 2.58e-12 Developmental language disorder (linguistic errors); LIHC cis rs9399135 1.000 rs35123050 chr6:135302740 G/A cg22676075 chr6:135203613 NA 0.38 6.24 0.32 1.26e-9 Red blood cell count; LIHC cis rs4853012 0.838 rs58759652 chr2:74344902 A/T cg19729930 chr2:74357872 NA 0.81 17.55 0.69 1.22e-49 Gestational age at birth (maternal effect); LIHC cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.57 0.33 1.91e-10 Bipolar disorder; LIHC cis rs7107174 0.892 rs11601195 chr11:78073501 A/G cg02023728 chr11:77925099 USP35 0.46 8.81 0.43 6.43e-17 Testicular germ cell tumor; LIHC cis rs17253792 0.822 rs10142497 chr14:56047948 C/T cg01858014 chr14:56050164 KTN1 0.73 8.07 0.4 1.21e-14 Putamen volume; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg01171360 chr6:293285 DUSP22 -0.5 -7.58 -0.38 3.17e-13 Menopause (age at onset); LIHC cis rs10779751 0.690 rs28729193 chr1:11180151 T/C cg08854313 chr1:11322531 MTOR -0.78 -10.25 -0.48 1.13e-21 Body mass index; LIHC cis rs7726839 0.574 rs12522955 chr5:639231 C/A cg09021430 chr5:549028 NA -0.42 -8.39 -0.41 1.26e-15 Obesity-related traits; LIHC cis rs950169 0.650 rs12902052 chr15:85125838 A/T cg03959625 chr15:84868606 LOC388152 0.45 6.1 0.31 2.82e-9 Schizophrenia; LIHC cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.66 -0.46 1.13e-19 Bipolar disorder; LIHC cis rs11229555 0.874 rs11229505 chr11:58274155 T/C cg15696309 chr11:58395628 NA -0.72 -8.61 -0.42 2.64e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs10751667 0.643 rs10794352 chr11:946294 T/C cg10932868 chr11:921992 NA 0.4 7.54 0.38 4.38e-13 Alzheimer's disease (late onset); LIHC trans rs10506458 0.915 rs998506 chr12:63400017 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.73 -10.4 -0.49 3.54e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg06481639 chr22:41940642 POLR3H -0.69 -7.0 -0.35 1.39e-11 Vitiligo; LIHC cis rs2075371 0.764 rs1643034 chr7:134006176 A/G cg20476274 chr7:133979776 SLC35B4 0.71 12.1 0.55 2.66e-28 Mean platelet volume; LIHC cis rs739401 0.572 rs384490 chr11:3078885 A/C cg05729581 chr11:3078854 CARS -0.44 -6.13 -0.31 2.43e-9 Longevity; LIHC trans rs11165623 0.602 rs942904 chr1:97025708 C/T cg10631902 chr5:14652156 NA -0.25 -6.17 -0.32 1.89e-9 Hip circumference;Waist circumference; LIHC cis rs1577917 0.682 rs1173417 chr6:86403941 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.53 0.33 2.37e-10 Response to antipsychotic treatment; LIHC cis rs35306767 0.623 rs12354710 chr10:1114020 C/T cg26597838 chr10:835615 NA 0.67 6.03 0.31 4.23e-9 Eosinophil percentage of granulocytes; LIHC cis rs7131987 0.903 rs11050152 chr12:29404424 G/T cg21522988 chr12:29376872 FAR2 0.29 6.42 0.33 4.68e-10 QT interval; LIHC cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.08e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs1347297 0.526 rs890579 chr2:179263287 C/T cg14011486 chr1:26737247 LIN28 0.49 7.67 0.38 1.81e-13 Alzheimer disease and age of onset; LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg26338869 chr17:61819248 STRADA 0.52 6.91 0.35 2.31e-11 Height; LIHC cis rs9814567 1.000 rs7433663 chr3:134235790 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg08219700 chr8:58056026 NA 0.5 6.81 0.35 4.4e-11 Developmental language disorder (linguistic errors); LIHC trans rs9951602 0.512 rs7240758 chr18:76650677 T/C cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC cis rs7552167 0.925 rs7546025 chr1:24510252 T/C cg01960748 chr1:24522592 NA -0.76 -9.18 -0.44 4.28e-18 Psoriasis vulgaris; LIHC cis rs7131987 0.622 rs7294598 chr12:29531989 A/C cg12903224 chr12:29470962 FAR2 0.39 6.36 0.33 6.41e-10 QT interval; LIHC cis rs912057 0.632 rs1294432 chr6:6745027 C/T cg06612196 chr6:6737390 NA 0.51 9.54 0.46 2.81e-19 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs7312774 0.618 rs3803122 chr12:107354680 G/A cg16260113 chr12:107380972 MTERFD3 0.85 11.06 0.51 1.61e-24 Severe influenza A (H1N1) infection; LIHC cis rs12479064 0.671 rs4851207 chr2:100105775 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -7.0 -0.35 1.35e-11 Chronic sinus infection; LIHC cis rs8180040 0.764 rs4682852 chr3:47177772 C/T cg27129171 chr3:47204927 SETD2 0.69 12.39 0.56 2.18e-29 Colorectal cancer; LIHC cis rs611744 0.967 rs536860 chr8:109230722 A/C cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs6594499 0.564 rs12518884 chr5:110452223 A/G cg04022379 chr5:110408740 TSLP 0.55 9.14 0.44 5.47e-18 Allergic disease (asthma, hay fever or eczema); LIHC cis rs539514 0.664 rs634729 chr13:76307981 C/T cg04757411 chr13:76259545 LMO7 -0.43 -7.34 -0.37 1.57e-12 Type 1 diabetes; LIHC cis rs4727027 0.704 rs4727031 chr7:148908305 T/C cg23583168 chr7:148888333 NA -0.68 -10.66 -0.5 4.24e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg09048334 chr6:37012640 NA 0.49 6.07 0.31 3.34e-9 Lung function (FEV1); LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs3820068 0.705 rs11589076 chr1:15827027 C/T cg17385448 chr1:15911702 AGMAT 0.38 6.34 0.32 7.41e-10 Systolic blood pressure; LIHC cis rs7044106 0.791 rs4837792 chr9:123483559 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.2 0.52 5.37e-25 Hip circumference adjusted for BMI; LIHC cis rs9911578 1.000 rs12938772 chr17:56776320 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.77 -0.43 8.52e-17 Intelligence (multi-trait analysis); LIHC cis rs9911578 1.000 rs304299 chr17:56838472 C/G cg12560992 chr17:57184187 TRIM37 0.97 17.46 0.69 2.94e-49 Intelligence (multi-trait analysis); LIHC cis rs7216064 0.589 rs8072723 chr17:66056970 T/A cg12091567 chr17:66097778 LOC651250 0.86 14.37 0.61 6.07e-37 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg17971929 chr21:40555470 PSMG1 0.87 10.43 0.49 2.62e-22 Cognitive function; LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs7605378 0.528 rs281767 chr2:200823281 C/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 7.47 0.37 6.88e-13 Osteoporosis; LIHC cis rs2455601 0.935 rs12049908 chr11:8919309 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.47 -6.36 -0.33 6.52e-10 Schizophrenia; LIHC cis rs7208859 0.673 rs73277967 chr17:29184166 T/A cg13385521 chr17:29058706 SUZ12P 0.84 8.15 0.4 7.08e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs858239 0.632 rs1985769 chr7:23122506 T/G cg23682824 chr7:23144976 KLHL7 0.41 6.2 0.32 1.6e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs35883536 0.587 rs2809799 chr1:101036516 A/G cg14515779 chr1:101123966 NA -0.43 -6.11 -0.31 2.67e-9 Monocyte count; LIHC cis rs4423214 0.550 rs4944885 chr11:71114075 C/T cg05163923 chr11:71159392 DHCR7 0.74 11.39 0.52 1.02e-25 Vitamin D levels; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.63 0.38 2.37e-13 Prudent dietary pattern; LIHC cis rs10896135 0.526 rs624561 chr11:66414915 C/T cg24851651 chr11:66362959 CCS -0.37 -6.11 -0.31 2.75e-9 Bipolar disorder; LIHC trans rs2832191 0.740 rs2832177 chr21:30478353 G/A cg14791747 chr16:20752902 THUMPD1 0.45 6.4 0.33 5.07e-10 Dental caries; LIHC cis rs7587476 0.906 rs2734674 chr2:215658895 A/G cg04004882 chr2:215674386 BARD1 -0.52 -6.96 -0.35 1.74e-11 Neuroblastoma; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg11494091 chr17:61959527 GH2 0.44 8.04 0.4 1.47e-14 Prudent dietary pattern; LIHC cis rs2637030 0.559 rs2637027 chr5:52980471 G/A cg06476337 chr5:52856530 NDUFS4 0.42 6.66 0.34 1.1e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs6912958 0.630 rs9450726 chr6:88236728 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.4 -6.64 -0.34 1.23e-10 Monocyte percentage of white cells; LIHC cis rs826838 1.000 rs10875717 chr12:38911174 T/C cg13010199 chr12:38710504 ALG10B 0.6 7.29 0.37 2.21e-12 Heart rate; LIHC cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg12751644 chr20:60527061 NA -0.38 -6.41 -0.33 4.81e-10 Body mass index; LIHC cis rs875971 0.895 rs1833495 chr7:65921595 T/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs6918586 0.658 rs13161 chr6:26114702 C/T cg18357526 chr6:26021779 HIST1H4A -0.55 -8.19 -0.41 5.15e-15 Schizophrenia; LIHC cis rs1816752 0.719 rs11841989 chr13:24997698 C/A cg22771759 chr13:24902376 NA 0.33 6.75 0.34 6.39e-11 Obesity-related traits; LIHC cis rs2455799 0.634 rs62243671 chr3:15921098 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 1.01e-12 Mean platelet volume; LIHC cis rs600806 0.850 rs10745354 chr1:109931908 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs12200782 1.000 rs6456741 chr6:26617058 C/T cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs904251 0.523 rs2776874 chr6:37483197 C/T cg08126542 chr6:37504118 NA -0.35 -5.91 -0.3 8.4e-9 Cognitive performance; LIHC cis rs8072100 1.000 rs8072100 chr17:45674687 A/T cg19378624 chr17:45501242 LOC100272146;C17orf57 0.36 5.71 0.3 2.44e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs17818399 0.547 rs62134736 chr2:46766446 G/A cg02822958 chr2:46747628 ATP6V1E2 0.45 6.49 0.33 2.95e-10 Height; LIHC trans rs3783890 1.000 rs34625843 chr14:93793329 C/T cg02802420 chr16:69363236 PDF;COG8 0.32 6.32 0.32 8.12e-10 Body mass index; LIHC cis rs7296418 0.961 rs12425850 chr12:123501972 T/C cg06742321 chr12:123595122 PITPNM2 0.31 5.85 0.3 1.14e-8 Platelet count; LIHC cis rs78456975 1.000 rs11903168 chr2:1560497 C/G cg01028140 chr2:1542097 TPO -0.54 -6.44 -0.33 4.01e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs6754311 0.551 rs2304599 chr2:136528004 C/G cg25344623 chr2:136566232 LCT 0.33 6.31 0.32 8.42e-10 Mosquito bite size; LIHC cis rs7044106 0.708 rs2416760 chr9:123374639 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.7 0.38 1.46e-13 Hip circumference adjusted for BMI; LIHC cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg06634786 chr22:41940651 POLR3H 0.8 8.9 0.43 3.22e-17 Vitiligo; LIHC cis rs7086627 0.515 rs2125040 chr10:82208422 G/C cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs7520050 0.931 rs11211189 chr1:46261584 A/T cg03146154 chr1:46216737 IPP -0.4 -6.55 -0.33 2.11e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg10096929 chr1:156261403 TMEM79 0.41 6.77 0.34 5.47e-11 Tonsillectomy; LIHC cis rs908922 0.676 rs4845784 chr1:152494583 G/C cg20991723 chr1:152506922 NA 0.56 9.9 0.47 1.69e-20 Hair morphology; LIHC cis rs992157 0.560 rs12992937 chr2:219087072 A/T cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.22 -0.55 9.39e-29 Colorectal cancer; LIHC cis rs1801251 1.000 rs12987513 chr2:233622066 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.44 0.53 7.1e-26 Coronary artery disease; LIHC cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg14393609 chr7:65229607 NA -0.43 -6.36 -0.33 6.33e-10 Aortic root size; LIHC cis rs2075371 1.000 rs2598296 chr7:133992985 C/T cg20476274 chr7:133979776 SLC35B4 0.74 12.15 0.55 1.69e-28 Mean platelet volume; LIHC cis rs911119 0.913 rs13043266 chr20:23588127 C/T cg16589663 chr20:23618590 CST3 0.76 7.87 0.39 4.59e-14 Chronic kidney disease; LIHC cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg19774624 chr17:42201019 HDAC5 -0.67 -10.2 -0.48 1.6e-21 Total body bone mineral density; LIHC cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs1843834 0.858 rs6731785 chr2:225491143 A/G cg22509189 chr2:225307070 NA -0.64 -7.69 -0.38 1.5700000000000001e-13 IgE levels in asthmatics (D.p. specific); LIHC cis rs2842992 0.724 rs2273827 chr6:160211339 C/A cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs1215050 0.791 rs260893 chr4:98744785 A/C cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs75908454 1.000 rs75367524 chr6:169922592 G/A cg19338460 chr6:170058176 WDR27 -0.83 -7.45 -0.37 7.84e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg08161947 chr12:19592900 AEBP2 -0.53 -7.75 -0.39 1.04e-13 Bilirubin levels; LIHC cis rs763121 0.853 rs4821808 chr22:39065739 A/G cg14440974 chr22:39074834 NA -0.44 -7.16 -0.36 4.96e-12 Menopause (age at onset); LIHC cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.24 0.45 2.73e-18 Bipolar disorder; LIHC cis rs986417 1.000 rs1269984 chr14:60898138 C/G cg27398547 chr14:60952738 C14orf39 -0.76 -8.76 -0.43 9.24e-17 Gut microbiota (bacterial taxa); LIHC cis rs858239 0.539 rs4295546 chr7:23191021 C/T cg23682824 chr7:23144976 KLHL7 0.42 6.38 0.33 5.6e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs2439831 1.000 rs2444250 chr15:43785051 C/G cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.34e-9 Lung cancer in ever smokers; LIHC cis rs10193935 0.901 rs222479 chr2:42656857 T/G cg27598129 chr2:42591480 NA -0.71 -10.32 -0.49 6.67e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs66887589 0.748 rs28439855 chr4:120262256 G/A cg09307838 chr4:120376055 NA 0.47 7.2 0.36 3.81e-12 Diastolic blood pressure; LIHC cis rs2290405 0.527 rs4690332 chr4:910520 C/T cg04824913 chr4:887549 GAK -0.57 -9.04 -0.44 1.19e-17 Systemic sclerosis; LIHC cis rs9640161 0.702 rs11765692 chr7:150026567 C/T cg21361702 chr7:150065534 REPIN1 0.45 6.1 0.31 2.85e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs3106136 0.967 rs72665658 chr4:95144761 C/T cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.18 -0.4 5.45e-15 Capecitabine sensitivity; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11527367 chr1:144612646 C1orf152 0.39 6.12 0.31 2.56e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs963731 0.649 rs10779924 chr2:39208057 G/T cg04010122 chr2:39346883 SOS1 -0.66 -5.8 -0.3 1.52e-8 Corticobasal degeneration; LIHC cis rs2404602 0.647 rs3812909 chr15:77176200 A/T cg03037974 chr15:76606532 NA -0.61 -10.28 -0.49 8.86e-22 Blood metabolite levels; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg18538332 chr22:24372958 LOC391322 -0.55 -7.86 -0.39 5.1e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4891159 0.790 rs72975929 chr18:74144630 G/C cg24786174 chr18:74118243 ZNF516 -0.74 -13.36 -0.59 4.7e-33 Longevity; LIHC cis rs12594515 1.000 rs8029209 chr15:45993489 A/G cg19682013 chr15:45996608 NA 0.39 6.67 0.34 1.01e-10 Waist circumference;Weight; LIHC cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg11890956 chr21:40555474 PSMG1 1.03 14.59 0.62 7.75e-38 Cognitive function; LIHC cis rs2243480 0.901 rs778693 chr7:65872345 T/G cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs67478160 0.643 rs876002 chr14:104239697 G/A cg24130564 chr14:104152367 KLC1 -0.34 -5.74 -0.3 2.1e-8 Schizophrenia; LIHC cis rs2842992 1.000 rs2842992 chr6:160071159 G/A cg11366901 chr6:160182831 ACAT2 0.89 13.85 0.6 6.12e-35 Age-related macular degeneration (geographic atrophy); LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.38 -0.33 5.86e-10 Total body bone mineral density; LIHC trans rs1005277 0.579 rs1780116 chr10:38526621 C/T cg17830980 chr10:43048298 ZNF37B -0.52 -10.13 -0.48 2.91e-21 Extrinsic epigenetic age acceleration; LIHC cis rs7726839 0.507 rs56282020 chr5:596701 T/C cg09021430 chr5:549028 NA -0.42 -8.36 -0.41 1.65e-15 Obesity-related traits; LIHC cis rs13108904 0.905 rs34490749 chr4:1217981 A/G cg20887711 chr4:1340912 KIAA1530 0.47 6.51 0.33 2.63e-10 Obesity-related traits; LIHC cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.96 9.33 0.45 1.42e-18 Platelet count; LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg07677032 chr17:61819896 STRADA 0.43 6.31 0.32 8.57e-10 Prudent dietary pattern; LIHC cis rs916888 0.773 rs199445 chr17:44817408 C/T cg15921436 chr17:44337874 NA 0.64 6.52 0.33 2.59e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9911578 1.000 rs7216680 chr17:56988243 G/C cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs599083 0.530 rs2472415 chr11:68185616 T/C cg16797656 chr11:68205561 LRP5 -0.49 -7.64 -0.38 2.18e-13 Bone mineral density (spine); LIHC cis rs2832191 0.740 rs2832175 chr21:30475606 A/G cg08807101 chr21:30365312 RNF160 -0.78 -12.2 -0.55 1.13e-28 Dental caries; LIHC cis rs2228479 0.850 rs2302162 chr16:89845287 A/G cg00800038 chr16:89945340 TCF25 -0.63 -9.2 -0.45 3.57e-18 Skin colour saturation; LIHC cis rs6430585 0.583 rs12373779 chr2:136586840 A/C cg07169764 chr2:136633963 MCM6 1.34 20.98 0.75 2.15e-63 Corneal structure; LIHC cis rs10744422 0.920 rs897393 chr12:123312051 A/G cg25930673 chr12:123319894 HIP1R 0.83 10.81 0.5 1.27e-23 Schizophrenia; LIHC cis rs7582720 1.000 rs72926791 chr2:203822891 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs5167 0.506 rs11669173 chr19:45492559 G/A cg09555818 chr19:45449301 APOC2 -0.22 -6.36 -0.33 6.47e-10 Blood protein levels; LIHC cis rs908922 0.676 rs7529441 chr1:152531629 A/G cg20991723 chr1:152506922 NA -0.58 -10.08 -0.48 4.16e-21 Hair morphology; LIHC cis rs7216064 0.953 rs62086044 chr17:65970837 G/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.2 -0.45 3.51e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg22029157 chr1:209979665 IRF6 0.48 7.74 0.39 1.17e-13 Cleft lip with or without cleft palate; LIHC cis rs600806 0.821 rs3879451 chr1:109909269 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs9522267 0.535 rs914036 chr13:112235542 G/A cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs57244997 1.000 rs73026573 chr6:162405119 C/T cg17173639 chr6:162384350 PARK2 -0.6 -7.41 -0.37 1e-12 Mosquito bite size; LIHC cis rs9457247 1.000 rs2769347 chr6:167371737 T/A cg12798992 chr6:167411361 FGFR1OP -0.61 -9.78 -0.47 4.55e-20 Crohn's disease; LIHC cis rs1577917 0.771 rs7742201 chr6:86432930 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -12.95 -0.57 1.81e-31 Response to antipsychotic treatment; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg26338869 chr17:61819248 STRADA 0.59 8.47 0.42 7.56e-16 Prudent dietary pattern; LIHC cis rs965469 0.779 rs6051820 chr20:3365301 A/G cg25506879 chr20:3388711 C20orf194 -0.52 -6.32 -0.32 8.17e-10 IFN-related cytopenia; LIHC cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg20295408 chr7:1910781 MAD1L1 -0.42 -6.13 -0.31 2.39e-9 Bipolar disorder and schizophrenia; LIHC cis rs7255436 0.965 rs4044435 chr19:8448177 T/C cg10174797 chr19:8464628 RAB11B 0.44 6.07 0.31 3.31e-9 HDL cholesterol; LIHC cis rs6963495 0.818 rs73190189 chr7:105164452 G/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs4819052 0.851 rs13047104 chr21:46673562 T/G cg11663144 chr21:46675770 NA -0.32 -5.94 -0.31 7.17e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3008870 1.000 rs12132068 chr1:67451924 G/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.18e-8 Lymphocyte percentage of white cells; LIHC cis rs8072100 0.840 rs2136751 chr17:45456093 A/G cg08085267 chr17:45401833 C17orf57 -0.55 -8.33 -0.41 1.96e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7945718 0.875 rs7105783 chr11:12719794 A/G cg25843174 chr11:12811716 TEAD1 0.34 7.67 0.38 1.86e-13 Educational attainment (years of education); LIHC cis rs7116495 0.609 rs17161751 chr11:71688347 G/A cg26138937 chr11:71823887 C11orf51 1.31 10.34 0.49 5.49e-22 Severe influenza A (H1N1) infection; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg02562419 chr6:159049626 TMEM181 0.44 6.24 0.32 1.32e-9 Bilirubin levels; LIHC cis rs801193 0.591 rs4506088 chr7:66135457 G/A cg11764359 chr7:65958608 NA -0.75 -12.91 -0.57 2.44e-31 Aortic root size; LIHC cis rs16866061 0.515 rs11695326 chr2:225415134 A/G cg12698349 chr2:225449008 CUL3 0.91 21.23 0.75 2.15e-64 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs4319547 0.656 rs1553179 chr12:122831073 A/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.04 -0.36 1.06e-11 Body mass index; LIHC cis rs2153535 0.580 rs9379216 chr6:8481235 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs7582720 1.000 rs116382857 chr2:203751932 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs897984 0.683 rs13337900 chr16:30822409 G/A cg02466173 chr16:30829666 NA -0.44 -7.47 -0.37 6.73e-13 Dementia with Lewy bodies; LIHC cis rs2439831 0.850 rs544122 chr15:43775732 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.64 8.16 0.4 6.67e-15 Lung cancer in ever smokers; LIHC cis rs2637030 0.559 rs1559266 chr5:52851931 C/T cg06476337 chr5:52856530 NDUFS4 0.43 6.7 0.34 8.59e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04784014 chr7:5521290 FBXL18 0.46 6.73 0.34 7.35e-11 Pancreatic cancer; LIHC cis rs3770081 1.000 rs12620810 chr2:86391481 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.88 -9.79 -0.47 4.18e-20 Facial emotion recognition (sad faces); LIHC cis rs9902453 0.730 rs2020939 chr17:28550732 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.46 -6.82 -0.35 4.27e-11 Coffee consumption (cups per day); LIHC cis rs67311347 0.713 rs4974018 chr3:40307419 G/A cg18306943 chr3:40428807 ENTPD3 0.38 6.41 0.33 4.84e-10 Renal cell carcinoma; LIHC cis rs9814567 1.000 rs12490835 chr3:134223730 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.25 -0.55 7.24e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs5753618 0.561 rs2413049 chr22:31686144 A/G cg07713946 chr22:31675144 LIMK2 -0.44 -7.91 -0.39 3.52e-14 Colorectal cancer; LIHC cis rs17376456 0.877 rs17315943 chr5:93442830 T/C cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg13395646 chr4:1353034 KIAA1530 -0.4 -6.28 -0.32 1.06e-9 Obesity-related traits; LIHC cis rs17685 0.753 rs6465000 chr7:75787417 G/A cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10751667 0.666 rs7943140 chr11:973824 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.2 0.48 1.73e-21 Alzheimer's disease (late onset); LIHC cis rs2404602 0.583 rs12592501 chr15:76554790 C/A cg23625390 chr15:77176239 SCAPER 0.34 6.0 0.31 5.02e-9 Blood metabolite levels; LIHC cis rs2412488 0.893 rs6848887 chr4:54279292 A/G cg22241045 chr4:54363911 LNX1 -0.41 -6.71 -0.34 8.15e-11 DNA methylation (variation); LIHC cis rs3770081 1.000 rs78032828 chr2:86309032 G/A cg01119172 chr2:86362222 SNORD94;PTCD3 0.43 6.16 0.32 2.06e-9 Facial emotion recognition (sad faces); LIHC cis rs6087990 0.899 rs4911107 chr20:31374991 G/A cg13636640 chr20:31349939 DNMT3B 0.87 19.19 0.72 3.09e-56 Ulcerative colitis; LIHC cis rs1801251 1.000 rs4973053 chr2:233670099 G/A cg08000102 chr2:233561755 GIGYF2 -0.74 -11.15 -0.52 7.49e-25 Coronary artery disease; LIHC cis rs2153535 0.580 rs1577466 chr6:8444192 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.66 0.42 1.91e-16 Motion sickness; LIHC cis rs921968 0.643 rs2278529 chr2:219502132 C/T cg18887096 chr2:219472410 PLCD4 0.34 5.78 0.3 1.68e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs1866706 1.000 rs1866706 chr11:12867214 T/C cg25843174 chr11:12811716 TEAD1 -0.33 -6.95 -0.35 1.86e-11 Intelligence (multi-trait analysis); LIHC cis rs4934494 0.768 rs1926139 chr10:91513152 A/G cg19698084 chr10:91461284 KIF20B -0.44 -5.88 -0.3 9.5e-9 Red blood cell count; LIHC cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg07636037 chr3:49044803 WDR6 0.76 12.76 0.57 8.85e-31 Menarche (age at onset); LIHC cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.26e-9 Menopause (age at onset); LIHC trans rs11098499 0.754 rs11732087 chr4:120239831 A/G cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg05896524 chr21:47604654 C21orf56 0.46 6.97 0.35 1.61e-11 Testicular germ cell tumor; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16406212 chr2:24163862 UBXN2A 0.38 6.12 0.31 2.6e-9 Pancreatic cancer; LIHC cis rs4474465 0.790 rs7932315 chr11:78214878 G/A cg27205649 chr11:78285834 NARS2 0.38 5.87 0.3 1.06e-8 Alzheimer's disease (survival time); LIHC cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg03517284 chr6:25882590 NA 0.49 6.31 0.32 8.72e-10 Intelligence (multi-trait analysis); LIHC cis rs7224737 1.000 rs9903204 chr17:40288062 G/A cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs4631830 0.863 rs3123078 chr10:51524971 A/G cg20129853 chr10:51489980 NA 0.42 9.21 0.45 3.39e-18 Prostate-specific antigen levels; LIHC cis rs9394841 0.692 rs34073739 chr6:41829970 A/G cg17623882 chr6:41773611 USP49 -0.43 -5.78 -0.3 1.68e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs1003719 0.715 rs7277820 chr21:38580309 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.53 -0.49 1.22e-22 Eye color traits; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg21747090 chr2:27597821 SNX17 -0.46 -7.0 -0.35 1.37e-11 Total body bone mineral density; LIHC cis rs7224685 0.569 rs12453798 chr17:4017079 C/T cg09597638 chr17:3907349 NA 0.54 6.49 0.33 3.07e-10 Type 2 diabetes; LIHC cis rs12477438 0.798 rs4324365 chr2:99623845 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.92 -0.65 4.52e-43 Chronic sinus infection; LIHC trans rs11098499 0.909 rs71614422 chr4:120359340 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.9 0.47 1.78e-20 Corneal astigmatism; LIHC cis rs17152411 1.000 rs7083336 chr10:126590771 T/C cg07906193 chr10:126599966 NA 0.46 7.11 0.36 6.9e-12 Height; LIHC cis rs9296404 1 rs9296404 chr6:42925803 T/C cg10862848 chr6:42927986 GNMT -0.27 -6.48 -0.33 3.2e-10 Plasma homocysteine levels (post-methionine load test); LIHC trans rs78049276 0.688 rs1878406 chr4:148393664 C/T cg13149281 chr14:23389818 RBM23;PRMT5 -0.59 -7.72 -0.39 1.29e-13 Pulse pressure; LIHC cis rs2576037 0.562 rs9959877 chr18:44522293 T/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.74 -0.3 2.07e-8 Personality dimensions; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10463451 chr21:37432625 SETD4 0.58 7.51 0.38 5.12e-13 Lung function (FEV1/FVC); LIHC cis rs9303401 0.592 rs12936771 chr17:56725052 T/C cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg13012494 chr21:47604986 C21orf56 -0.38 -5.95 -0.31 6.79e-9 Testicular germ cell tumor; LIHC trans rs2243480 1.000 rs1546059 chr7:65654709 C/A cg10756647 chr7:56101905 PSPH -1.07 -13.13 -0.58 3.48e-32 Diabetic kidney disease; LIHC cis rs17102884 0.600 rs9671386 chr14:75151047 G/A cg08847533 chr14:75593920 NEK9 0.44 6.55 0.33 2.13e-10 Neuroticism; LIHC cis rs7187994 0.848 rs16974527 chr16:84782822 C/T cg07647771 chr16:84786436 USP10 -0.33 -6.47 -0.33 3.47e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs8060686 0.516 rs2290699 chr16:68289059 C/T cg05110241 chr16:68378359 PRMT7 -0.54 -6.51 -0.33 2.67e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs6840360 0.533 rs13121178 chr4:152729047 T/C cg22705602 chr4:152727874 NA 0.36 7.6 0.38 2.95e-13 Intelligence (multi-trait analysis); LIHC cis rs11718455 0.767 rs9861276 chr3:43989595 C/T cg08738300 chr3:44038990 NA 0.52 8.84 0.43 5.2e-17 Coronary artery disease; LIHC cis rs72781680 0.566 rs6714016 chr2:23899948 A/G cg08917208 chr2:24149416 ATAD2B 0.63 6.18 0.32 1.85e-9 Lymphocyte counts; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04130928 chr5:176449623 ZNF346 -0.52 -6.63 -0.34 1.29e-10 Systolic blood pressure; LIHC cis rs778371 0.723 rs6710294 chr2:233579634 T/C cg08000102 chr2:233561755 GIGYF2 0.88 14.7 0.62 2.92e-38 Schizophrenia; LIHC cis rs1005277 0.579 rs2474567 chr10:38382492 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg21280719 chr6:42927975 GNMT -0.31 -6.99 -0.35 1.49e-11 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs727809 0.927 rs4958336 chr5:152582060 A/T cg21580998 chr1:227751410 ZNF678 -0.48 -6.09 -0.31 3.02e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6762477 0.748 rs11717349 chr3:50223977 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.52 -7.96 -0.4 2.61e-14 Menarche (age at onset); LIHC cis rs3812831 0.629 rs7318527 chr13:114946956 C/T cg06611532 chr13:114900021 NA 0.41 7.4 0.37 1.04e-12 Schizophrenia; LIHC cis rs1639906 0.895 rs6972752 chr7:2196551 G/A cg02951883 chr7:2050386 MAD1L1 0.58 7.79 0.39 8.3e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs763014 0.932 rs2269559 chr16:682297 T/C cg00908189 chr16:619842 PIGQ 0.81 12.72 0.57 1.32e-30 Height; LIHC cis rs10870270 0.956 rs7894 chr10:133769482 G/C cg08754478 chr10:133766260 PPP2R2D -0.55 -8.05 -0.4 1.41e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9534288 0.797 rs2806922 chr13:46518059 A/G cg15192986 chr13:46630673 CPB2 -0.5 -7.75 -0.39 1.04e-13 Blood protein levels; LIHC cis rs7666738 0.571 rs7683769 chr4:99091742 T/C cg05340658 chr4:99064831 C4orf37 0.66 11.68 0.53 9.52e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs9457247 0.756 rs2345572 chr6:167403441 A/T cg23791538 chr6:167370224 RNASET2 -0.57 -8.93 -0.44 2.59e-17 Crohn's disease; LIHC cis rs12477438 0.520 rs2964969 chr2:99782811 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.35 0.77 7.7e-69 Chronic sinus infection; LIHC cis rs4423214 0.559 rs10898203 chr11:71203436 C/T cg05163923 chr11:71159392 DHCR7 -0.61 -7.41 -0.37 9.84e-13 Vitamin D levels; LIHC cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg04944784 chr2:26401820 FAM59B 0.7 9.26 0.45 2.3e-18 Gut microbiome composition (summer); LIHC trans rs7677751 0.848 rs4635872 chr4:55099041 C/A cg17183009 chr3:120277827 NA 0.52 6.13 0.31 2.45e-9 Corneal astigmatism; LIHC cis rs7937682 0.883 rs542831 chr11:111471392 T/A cg09085632 chr11:111637200 PPP2R1B -0.93 -11.29 -0.52 2.54e-25 Primary sclerosing cholangitis; LIHC cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg05665937 chr4:1216051 CTBP1 0.45 6.08 0.31 3.23e-9 Obesity-related traits; LIHC cis rs77633900 0.772 rs2469224 chr15:76651327 T/G cg21673338 chr15:77095150 SCAPER -0.53 -6.15 -0.32 2.15e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg19318889 chr4:1322082 MAEA 0.46 6.49 0.33 3.11e-10 Obesity-related traits; LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.65 0.38 2e-13 Prudent dietary pattern; LIHC cis rs1552244 0.554 rs2272120 chr3:10046703 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg11070056 chr1:107600091 PRMT6 -0.71 -12.16 -0.55 1.64e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs16912285 0.688 rs7128427 chr11:24338598 C/T ch.11.24196551F chr11:24239977 NA 0.72 8.27 0.41 3.09e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs8067354 0.645 rs1874548 chr17:57841357 A/G cg02344993 chr17:57696989 CLTC 0.71 11.85 0.54 2.25e-27 Hemoglobin concentration; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs244731 0.959 rs918459 chr5:176669030 C/T cg17509989 chr5:176798049 RGS14 -0.61 -5.93 -0.31 7.54e-9 Urate levels in lean individuals; LIHC cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg06481639 chr22:41940642 POLR3H -0.66 -6.47 -0.33 3.34e-10 Vitiligo; LIHC cis rs9858542 0.953 rs11922013 chr3:49458355 G/C cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs1059312 0.500 rs10734964 chr12:129286486 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.51 -7.8 -0.39 7.61e-14 Systemic lupus erythematosus; LIHC cis rs40363 0.729 rs6501176 chr16:3522197 A/G cg21433313 chr16:3507492 NAT15 -0.46 -6.39 -0.33 5.57e-10 Tuberculosis; LIHC trans rs2243480 1.000 rs2707844 chr7:66059509 G/A cg10756647 chr7:56101905 PSPH 1.01 11.98 0.54 7.24e-28 Diabetic kidney disease; LIHC cis rs875971 0.558 rs4433015 chr7:65639723 A/C cg11764359 chr7:65958608 NA -0.66 -8.86 -0.43 4.53e-17 Aortic root size; LIHC trans rs6952808 0.723 rs57216949 chr7:2030287 G/T cg04565464 chr8:145669602 NFKBIL2 0.4 6.65 0.34 1.16e-10 Bipolar disorder and schizophrenia; LIHC cis rs2439831 1.000 rs690436 chr15:43761205 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 13.91 0.6 3.46e-35 Lung cancer in ever smokers; LIHC trans rs8073060 0.586 rs225307 chr17:33918311 A/G cg19694781 chr19:47549865 TMEM160 1.23 12.68 0.57 1.86e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs6840360 1.000 rs6840678 chr4:152604331 C/G cg22705602 chr4:152727874 NA 0.31 6.33 0.32 7.53e-10 Intelligence (multi-trait analysis); LIHC cis rs2073300 1.000 rs6106669 chr20:23460328 C/T cg12062639 chr20:23401060 NAPB 0.8 9.83 0.47 3.06e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs801193 0.636 rs10233806 chr7:66118248 G/C cg18876405 chr7:65276391 NA -0.34 -6.15 -0.32 2.16e-9 Aortic root size; LIHC cis rs896854 0.738 rs509594 chr8:95967156 C/G cg09323728 chr8:95962352 TP53INP1 0.32 6.22 0.32 1.43e-9 Type 2 diabetes; LIHC cis rs2242116 0.793 rs9855938 chr3:46957298 G/A cg02527881 chr3:46936655 PTH1R -0.5 -10.55 -0.5 1.02e-22 Birth weight; LIHC cis rs1144333 0.655 rs1146602 chr1:76239309 A/G cg10523679 chr1:76189770 ACADM -0.45 -5.85 -0.3 1.16e-8 Attention function in attention deficit hyperactive disorder; LIHC cis rs12611088 0.634 rs2682566 chr19:44024942 G/T cg13740135 chr19:44006432 PHLDB3 -0.42 -6.09 -0.31 3.04e-9 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs11098499 0.780 rs7692994 chr4:120427489 C/A cg09307838 chr4:120376055 NA 0.66 10.4 0.49 3.51e-22 Corneal astigmatism; LIHC cis rs3096299 0.559 rs9931073 chr16:89568513 G/C cg08392591 chr16:89556376 ANKRD11 0.44 6.77 0.34 5.78e-11 Multiple myeloma (IgH translocation); LIHC cis rs7264396 0.790 rs6060518 chr20:34217309 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -9.59 -0.46 1.88e-19 Total cholesterol levels; LIHC cis rs9911578 1.000 rs11869828 chr17:56609525 G/A cg12560992 chr17:57184187 TRIM37 -0.98 -17.72 -0.69 2.58e-50 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg08280861 chr8:58055591 NA 0.54 6.29 0.32 9.97e-10 Developmental language disorder (linguistic errors); LIHC cis rs477895 1.000 rs7939107 chr11:64034773 C/T cg04317338 chr11:64019027 PLCB3 0.84 8.41 0.41 1.14e-15 Mean platelet volume; LIHC cis rs3820068 0.705 rs72643683 chr1:15824905 C/A cg17385448 chr1:15911702 AGMAT 0.38 6.34 0.32 7.41e-10 Systolic blood pressure; LIHC trans rs7246657 0.943 rs7253091 chr19:37967214 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg05368731 chr17:41323189 NBR1 0.73 12.38 0.56 2.46e-29 Menopause (age at onset); LIHC cis rs10540 1.000 rs61742833 chr11:490035 C/T cg03576123 chr11:487126 PTDSS2 -1.06 -7.04 -0.36 1.09e-11 Body mass index; LIHC cis rs3540 0.557 rs11634314 chr15:91042066 A/C cg22089800 chr15:90895588 ZNF774 -0.59 -8.08 -0.4 1.16e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12374732 chr8:103251909 RRM2B 0.46 6.42 0.33 4.65e-10 Lung function (FEV1/FVC); LIHC cis rs8062405 1.000 rs55991577 chr16:28843025 C/T cg07451762 chr16:28383216 NA 0.32 6.09 0.31 3.1e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1403694 0.515 rs1648697 chr3:186449194 A/G cg12454167 chr3:186435060 KNG1 0.3 7.05 0.36 1.01e-11 Blood protein levels; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg10150615 chr22:24372951 LOC391322 0.56 8.45 0.42 8.62e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6665290 0.904 rs1343744 chr1:227183022 C/T cg10327440 chr1:227177885 CDC42BPA -1.19 -26.16 -0.82 1.28e-83 Myeloid white cell count; LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.56 -7.77 -0.39 9.34e-14 Lymphocyte counts; LIHC cis rs7716219 0.672 rs10940473 chr5:54873285 C/T cg14753740 chr5:54468940 CDC20B;MIR449C 0.51 7.19 0.36 4.18e-12 Height; LIHC cis rs6430585 0.528 rs12474975 chr2:136702118 A/T cg25344623 chr2:136566232 LCT -0.37 -5.91 -0.3 8.3e-9 Corneal structure; LIHC trans rs11875537 0.867 rs622943 chr18:2299472 A/T cg06226973 chr2:179315633 PRKRA;MIR548N;DFNB59 0.43 6.27 0.32 1.1e-9 Brain volume in infants (cerebrospinal fluid); LIHC cis rs9325144 0.581 rs2730929 chr12:38942739 T/C cg26384229 chr12:38710491 ALG10B -0.44 -6.86 -0.35 3.27e-11 Morning vs. evening chronotype; LIHC cis rs644799 0.965 rs11021305 chr11:95498269 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.65 9.01 0.44 1.53e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.43 0.62 3.54e-37 Prudent dietary pattern; LIHC cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg23758822 chr17:41437982 NA 0.98 18.38 0.7 5.65e-53 Menopause (age at onset); LIHC cis rs1552244 0.882 rs67762674 chr3:10014485 C/T cg08888203 chr3:10149979 C3orf24 0.49 6.13 0.31 2.4e-9 Alzheimer's disease; LIHC cis rs700651 0.821 rs700663 chr2:198670478 T/A cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.42e-11 Intracranial aneurysm; LIHC cis rs7552404 0.924 rs67757078 chr1:76169456 G/A cg10523679 chr1:76189770 ACADM 0.67 10.01 0.48 7.42e-21 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6782228 0.606 rs1697 chr3:128356852 C/T cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7072216 0.763 rs7914401 chr10:100163928 A/G cg26618903 chr10:100175079 PYROXD2 -0.39 -6.32 -0.32 8.08e-10 Metabolite levels; LIHC cis rs875971 0.660 rs10263935 chr7:66096028 A/G cg11764359 chr7:65958608 NA 0.68 10.28 0.49 9.12e-22 Aortic root size; LIHC cis rs61041384 0.661 rs3759111 chr12:123687774 A/G cg00376283 chr12:123451042 ABCB9 0.58 6.43 0.33 4.2e-10 Schizophrenia; LIHC cis rs7937890 0.732 rs7946902 chr11:14273308 C/T cg22961513 chr11:14280813 SPON1 0.48 7.31 0.37 1.9e-12 Mitochondrial DNA levels; LIHC cis rs8180040 0.726 rs1463393 chr3:46994987 G/A cg02527881 chr3:46936655 PTH1R 0.32 6.4 0.33 5.18e-10 Colorectal cancer; LIHC cis rs9918079 0.560 rs10008975 chr4:15624571 C/T cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.85 -0.3 1.14e-8 Obesity-related traits; LIHC trans rs8117834 0.574 rs6086331 chr20:8083296 G/A cg00593689 chr4:53575888 NA 0.38 6.5 0.33 2.77e-10 Chronic kidney disease; LIHC cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg13271783 chr10:134563150 INPP5A 0.6 7.4 0.37 1.09e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9926296 0.715 rs2115401 chr16:89740609 A/G cg08949735 chr16:89699720 DPEP1 0.41 8.2 0.41 4.91e-15 Vitiligo; LIHC cis rs9341808 0.718 rs910266 chr6:80921170 A/T cg08355045 chr6:80787529 NA 0.36 7.52 0.38 4.8e-13 Sitting height ratio; LIHC cis rs7106204 0.514 rs7935857 chr11:24252420 C/T ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.24e-27 Response to Homoharringtonine (cytotoxicity); LIHC cis rs8180040 0.647 rs57756484 chr3:47239333 A/G cg27129171 chr3:47204927 SETD2 -0.57 -9.44 -0.45 5.85e-19 Colorectal cancer; LIHC cis rs769267 0.965 rs2965188 chr19:19522557 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.87 0.3 1.03e-8 Tonsillectomy; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15106226 chr19:11878036 ZNF441 -0.54 -6.09 -0.31 2.99e-9 Systolic blood pressure; LIHC cis rs1005277 0.563 rs2505216 chr10:38482830 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.27 -0.32 1.06e-9 Extrinsic epigenetic age acceleration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25463822 chr1:193028375 TROVE2;UCHL5 -0.55 -6.63 -0.34 1.29e-10 Systolic blood pressure; LIHC cis rs243505 0.762 rs734002 chr7:148505788 A/G cg09806900 chr7:148480153 CUL1 0.43 6.43 0.33 4.3e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1000083 0.599 rs7734922 chr5:96745629 G/T ch.5.96698337R chr5:96672581 NA 0.74 6.26 0.32 1.13e-9 Cisplatin-induced ototoxicity; LIHC cis rs7845219 0.539 rs713113 chr8:95877787 C/T cg16049864 chr8:95962084 TP53INP1 0.52 8.99 0.44 1.72e-17 Type 2 diabetes; LIHC cis rs13126513 0.708 rs2172138 chr4:100489785 G/C cg05468953 chr4:100565104 NA 0.32 6.06 0.31 3.64e-9 Metabolite levels (MHPG); LIHC cis rs7098414 0.511 rs7899545 chr10:82150635 G/C cg01528321 chr10:82214614 TSPAN14 0.42 6.35 0.32 6.89e-10 Post bronchodilator FEV1; LIHC cis rs4478037 0.822 rs9817393 chr3:33117069 A/G cg27203090 chr3:33138513 GLB1;TMPPE -0.58 -7.42 -0.37 9.39e-13 Major depressive disorder; LIHC cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.77 -0.34 5.51e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1577917 0.883 rs13212415 chr6:86608083 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.23 -0.36 3.14e-12 Response to antipsychotic treatment; LIHC cis rs7578199 0.744 rs7590080 chr2:242205466 C/T cg19372975 chr2:242212901 HDLBP -0.61 -5.84 -0.3 1.2e-8 Chronic lymphocytic leukemia; LIHC cis rs7542091 0.748 rs2357231 chr1:210028454 A/C cg22029157 chr1:209979665 IRF6 -0.37 -6.17 -0.32 1.96e-9 Monobrow; LIHC trans rs66573146 0.572 rs66819208 chr4:6946128 A/G cg07817883 chr1:32538562 TMEM39B 1.03 9.14 0.44 5.57e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs6942756 1.000 rs66970518 chr7:128871006 G/A cg02491457 chr7:128862824 NA -0.71 -11.27 -0.52 2.84e-25 White matter hyperintensity burden; LIHC cis rs35110281 0.807 rs9984002 chr21:45061501 T/C cg04455712 chr21:45112962 RRP1B 0.46 7.86 0.39 5.1e-14 Mean corpuscular volume; LIHC trans rs561341 0.882 rs2521594 chr17:30302087 C/T cg20587970 chr11:113659929 NA -1.38 -11.71 -0.53 7.6e-27 Hip circumference adjusted for BMI; LIHC cis rs950169 0.840 rs12905223 chr15:85114268 T/C cg12863693 chr15:85201151 NMB 0.44 6.16 0.32 2.01e-9 Schizophrenia; LIHC cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10744422 0.748 rs1671688 chr12:123255733 A/T cg18912006 chr12:123335444 HIP1R -0.52 -6.13 -0.31 2.41e-9 Schizophrenia; LIHC cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg02931644 chr1:25747376 RHCE 0.33 7.06 0.36 9.29e-12 Erythrocyte sedimentation rate; LIHC cis rs6665290 0.935 rs12409755 chr1:227196949 A/T cg10327440 chr1:227177885 CDC42BPA -1.19 -25.41 -0.81 8.99e-81 Myeloid white cell count; LIHC cis rs12477438 0.765 rs6749059 chr2:99591021 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -11.09 -0.51 1.29e-24 Chronic sinus infection; LIHC cis rs12479064 0.724 rs2305352 chr2:100015124 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.65 -8.15 -0.4 7.09e-15 Chronic sinus infection; LIHC cis rs9549367 0.789 rs57747440 chr13:113894750 C/A cg00898013 chr13:113819073 PROZ -0.42 -7.35 -0.37 1.46e-12 Platelet distribution width; LIHC cis rs6701037 1.000 rs6659824 chr1:175125378 C/A cg17845761 chr1:175162550 KIAA0040 -0.35 -5.74 -0.3 2.11e-8 Alcohol dependence; LIHC cis rs6964587 1.000 rs12533199 chr7:91757393 C/T cg17063962 chr7:91808500 NA 1.02 19.69 0.73 3.16e-58 Breast cancer; LIHC cis rs72653721 0.793 rs4713100 chr6:10968216 T/C cg13562911 chr6:11044106 ELOVL2 0.48 6.83 0.35 3.96e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs895636 0.848 rs4953156 chr2:45189763 G/A cg16198908 chr2:45192207 NA 0.39 5.94 0.31 6.97e-9 Metabolite levels;Fasting plasma glucose; LIHC cis rs9902453 0.845 rs72823935 chr17:28008595 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.71 11.51 0.53 4.03e-26 Coffee consumption (cups per day); LIHC cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg11952622 chr19:58962976 ZNF324B 0.47 7.13 0.36 5.94e-12 Uric acid clearance; LIHC cis rs4819052 0.851 rs2838857 chr21:46681000 A/G cg22633049 chr21:46681294 NA -0.36 -6.3 -0.32 9.33e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1005277 0.565 rs2474565 chr10:38380828 A/G cg27523141 chr10:43048294 ZNF37B 0.37 6.27 0.32 1.09e-9 Extrinsic epigenetic age acceleration; LIHC cis rs16958440 1.000 rs62096476 chr18:44658621 T/C cg17192377 chr18:44677553 HDHD2 0.6 6.71 0.34 8.24e-11 Sitting height ratio; LIHC cis rs1034435 1.000 rs9680744 chr22:48889547 C/G cg05992904 chr22:48892994 FAM19A5 -0.46 -9.09 -0.44 8.24e-18 Late-onset Alzheimer's disease; LIHC cis rs7116495 0.609 rs7924834 chr11:71644333 C/T cg26138937 chr11:71823887 C11orf51 1.09 9.77 0.47 4.79e-20 Severe influenza A (H1N1) infection; LIHC trans rs412658 0.776 rs12460025 chr19:22318230 A/G cg05197062 chr11:11642011 GALNTL4 -0.46 -6.4 -0.33 5e-10 Telomere length; LIHC cis rs1559088 0.948 rs2019603 chr19:33577367 C/T cg17764715 chr19:33622953 WDR88 -0.45 -6.65 -0.34 1.13e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs507080 0.961 rs4938523 chr11:118548838 G/T cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC cis rs116095464 0.558 rs9312957 chr5:202194 C/T cg22496380 chr5:211416 CCDC127 -1.19 -10.59 -0.5 7.59e-23 Breast cancer; LIHC cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg08888203 chr3:10149979 C3orf24 0.57 6.49 0.33 3.06e-10 Alzheimer's disease; LIHC cis rs68170813 0.562 rs11770061 chr7:107071310 A/G cg02696742 chr7:106810147 HBP1 -0.5 -5.74 -0.3 2.1e-8 Coronary artery disease; LIHC cis rs4927850 1.000 rs7614767 chr3:195753451 C/T cg01181863 chr3:195395398 SDHAP2 -0.47 -6.12 -0.31 2.61e-9 Pancreatic cancer; LIHC cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg06453172 chr10:134556979 INPP5A 0.65 8.47 0.42 7.58e-16 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2204008 0.506 rs11495470 chr12:38026904 C/T cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs11677370 0.561 rs12711973 chr2:3825339 C/G cg17052675 chr2:3827356 NA -0.51 -6.88 -0.35 2.81e-11 Type 2 diabetes; LIHC cis rs8027181 0.839 rs8033073 chr15:73051093 G/A cg25632853 chr15:73088954 NA 0.37 6.17 0.32 1.95e-9 Triglyceride levels; LIHC cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg00750074 chr16:89608354 SPG7 -0.45 -7.24 -0.36 3.07e-12 Multiple myeloma (IgH translocation); LIHC cis rs11098499 0.708 rs10005237 chr4:120237897 T/C cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg20607798 chr8:58055168 NA 0.48 5.98 0.31 5.72e-9 Developmental language disorder (linguistic errors); LIHC cis rs9486715 0.867 rs9373887 chr6:96957004 C/T cg06623918 chr6:96969491 KIAA0776 0.86 15.12 0.63 6.25e-40 Headache; LIHC cis rs1552244 0.832 rs17050674 chr3:10027258 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.57 -0.5 8.95e-23 Alzheimer's disease; LIHC cis rs365132 0.875 rs4490607 chr5:176349386 T/C cg16309518 chr5:176445507 NA -0.52 -9.6 -0.46 1.78e-19 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs9296092 0.560 rs17627049 chr6:33537802 G/T cg13560919 chr6:33536144 NA -0.39 -6.64 -0.34 1.25e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs9326778 0.520 rs11957948 chr5:108850012 G/T cg17395555 chr5:108820864 NA -0.36 -6.2 -0.32 1.67e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs6502050 0.835 rs7501527 chr17:80099355 A/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.93 -0.31 7.43e-9 Life satisfaction; LIHC cis rs7412746 0.611 rs12085336 chr1:150775780 A/T cg18016565 chr1:150552671 MCL1 0.5 9.91 0.47 1.67e-20 Melanoma; LIHC cis rs12530845 0.887 rs59400686 chr7:135360029 A/G cg23117316 chr7:135346802 PL-5283 -0.37 -5.75 -0.3 1.98e-8 Red blood cell traits; LIHC cis rs10504229 0.679 rs2317991 chr8:58035080 C/T cg02290350 chr8:58132656 NA -0.32 -7.41 -0.37 9.98e-13 Developmental language disorder (linguistic errors); LIHC cis rs344364 0.511 rs1657134 chr16:1953127 A/G cg26897989 chr16:1907736 C16orf73 -0.47 -5.89 -0.3 9.03e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs2531992 0.686 rs2041247 chr16:4032581 A/G cg05927578 chr16:4029543 ADCY9 0.51 7.18 0.36 4.45e-12 Waist circumference; LIHC trans rs2270927 0.510 rs246813 chr5:75599605 G/T cg13563193 chr19:33072644 PDCD5 1.0 9.95 0.47 1.14e-20 Mean corpuscular volume; LIHC cis rs3806843 0.735 rs2530242 chr5:140053351 G/C cg19875535 chr5:140030758 IK -0.41 -6.68 -0.34 9.76e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs6545883 0.894 rs6760075 chr2:61612881 C/A cg15711740 chr2:61764176 XPO1 0.42 5.85 0.3 1.13e-8 Tuberculosis; LIHC cis rs8077889 0.917 rs72836545 chr17:41892602 A/G cg26893861 chr17:41843967 DUSP3 1.0 11.04 0.51 1.94e-24 Triglycerides; LIHC cis rs6912958 0.967 rs6914299 chr6:88149176 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.29 -0.37 2.13e-12 Monocyte percentage of white cells; LIHC cis rs6061231 0.631 rs2427318 chr20:60975727 G/T cg24112000 chr20:60950667 NA -0.61 -9.86 -0.47 2.42e-20 Colorectal cancer; LIHC cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg08888203 chr3:10149979 C3orf24 0.62 6.93 0.35 2.15e-11 Alzheimer's disease; LIHC cis rs72615157 0.539 rs72615159 chr7:99674286 G/A cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.4 5.71 0.3 2.43e-8 Lung function (FEV1/FVC); LIHC cis rs17401966 0.931 rs10492972 chr1:10353112 A/G cg15208524 chr1:10270712 KIF1B 0.41 6.37 0.33 6.22e-10 Hepatocellular carcinoma; LIHC cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg23758822 chr17:41437982 NA 0.97 17.99 0.7 2.07e-51 Menopause (age at onset); LIHC cis rs1816752 0.905 rs7995492 chr13:25013023 A/T cg22771759 chr13:24902376 NA 0.32 6.79 0.34 4.99e-11 Obesity-related traits; LIHC cis rs2625529 0.938 rs4238447 chr15:72131880 C/T cg16672083 chr15:72433130 SENP8 -0.32 -5.99 -0.31 5.36e-9 Red blood cell count; LIHC cis rs7264396 0.635 rs6060660 chr20:34476649 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -10.5 -0.49 1.54e-22 Total cholesterol levels; LIHC cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 11.36 0.52 1.36e-25 Platelet count; LIHC cis rs1371867 0.846 rs924057 chr8:101266157 A/G cg06636551 chr8:101224915 SPAG1 0.49 9.27 0.45 2.12e-18 Atrioventricular conduction; LIHC cis rs9814567 1.000 rs7645295 chr3:134307734 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.14 -0.55 1.84e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs909002 0.849 rs4949449 chr1:32088534 T/G cg13919466 chr1:32135498 COL16A1 -0.33 -6.28 -0.32 1.05e-9 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs2204008 0.537 rs11170128 chr12:38006632 G/A cg26384229 chr12:38710491 ALG10B 0.84 10.35 0.49 4.9e-22 Bladder cancer; LIHC cis rs7312933 0.703 rs1059360 chr12:42554505 A/G cg01256987 chr12:42539512 GXYLT1 -0.44 -7.19 -0.36 4.15e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11605275 1.000 rs78687006 chr11:20032176 G/A cg14835545 chr11:20032148 NAV2 -0.8 -7.38 -0.37 1.18e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs600806 0.850 rs10858086 chr1:109915075 C/A cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.19 -0.36 4.1e-12 Intelligence (multi-trait analysis); LIHC cis rs1113500 0.933 rs745795 chr1:108629345 C/T cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.92e-12 Growth-regulated protein alpha levels; LIHC cis rs6450176 0.585 rs255761 chr5:53321956 G/T ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.48 -0.62 2.09e-37 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs4788570 0.615 rs7188675 chr16:71680002 C/T cg06353428 chr16:71660113 MARVELD3 1.45 15.6 0.64 8.48e-42 Intelligence (multi-trait analysis); LIHC trans rs668210 0.793 rs534201 chr11:65776728 A/T cg17712092 chr4:129076599 LARP1B 0.59 6.27 0.32 1.08e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9549367 0.789 rs9549718 chr13:113909822 A/G cg18105134 chr13:113819100 PROZ -0.68 -11.57 -0.53 2.28e-26 Platelet distribution width; LIHC cis rs8062405 0.755 rs7193402 chr16:28586127 A/G cg07451762 chr16:28383216 NA 0.39 7.01 0.35 1.3e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2204008 0.811 rs4882300 chr12:38415224 A/T cg26384229 chr12:38710491 ALG10B -0.58 -8.3 -0.41 2.47e-15 Bladder cancer; LIHC cis rs2120019 1.000 rs12324912 chr15:75361006 G/A cg09165964 chr15:75287851 SCAMP5 -0.65 -10.51 -0.49 1.47e-22 Blood trace element (Zn levels); LIHC cis rs7937890 0.504 rs2575822 chr11:14519851 C/A cg02886208 chr11:14281011 SPON1 -0.43 -6.12 -0.31 2.56e-9 Mitochondrial DNA levels; LIHC trans rs208520 0.690 rs12201219 chr6:66748862 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.93 0.43 2.63e-17 Exhaled nitric oxide output; LIHC cis rs6728642 0.519 rs59131346 chr2:97566768 C/T cg26665480 chr2:98280029 ACTR1B -0.6 -6.51 -0.33 2.75e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs9814567 1.000 rs6765505 chr3:134208132 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.07e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs68170813 0.559 rs17349904 chr7:106897237 A/C cg02696742 chr7:106810147 HBP1 -0.52 -5.96 -0.31 6.44e-9 Coronary artery disease; LIHC cis rs8060686 0.516 rs7184821 chr16:68270229 T/C cg05110241 chr16:68378359 PRMT7 -0.52 -6.11 -0.31 2.77e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs7208859 0.673 rs78799101 chr17:29215160 A/T cg13385521 chr17:29058706 SUZ12P 0.82 7.94 0.39 2.98e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs709400 1.000 rs3915733 chr14:104147353 G/A cg26031613 chr14:104095156 KLC1 1.06 14.08 0.61 7.59e-36 Body mass index; LIHC cis rs428668 0.681 rs192193 chr5:150692590 A/G cg11125805 chr5:150678162 SLC36A3 0.4 8.1 0.4 1.01e-14 Skin aging (microtopography measurement); LIHC cis rs8180040 0.966 rs12486969 chr3:47429003 G/C cg16586182 chr3:47516702 SCAP 0.6 11.82 0.54 2.88e-27 Colorectal cancer; LIHC cis rs6088813 1.000 rs6087702 chr20:33995945 T/A cg14752227 chr20:34000481 UQCC -0.4 -5.75 -0.3 1.99e-8 Height; LIHC cis rs6809651 0.524 rs6444105 chr3:185811301 C/T cg00760338 chr3:185826511 ETV5 -0.84 -12.56 -0.56 5.15e-30 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs151997 0.962 rs27476 chr5:50178160 A/T cg06027927 chr5:50259733 NA -0.56 -7.5 -0.38 5.52e-13 Callous-unemotional behaviour; LIHC cis rs7772486 0.686 rs857882 chr6:145969716 T/G cg23711669 chr6:146136114 FBXO30 -0.7 -12.65 -0.56 2.45e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs9381040 0.655 rs9381032 chr6:41044986 A/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.42 -6.62 -0.34 1.42e-10 Alzheimer's disease (late onset); LIHC cis rs3096299 0.679 rs3102338 chr16:89442250 C/G cg01788221 chr16:89496183 ANKRD11 -0.43 -6.66 -0.34 1.09e-10 Multiple myeloma (IgH translocation); LIHC cis rs7412746 0.586 rs2864882 chr1:150883037 C/T cg17724175 chr1:150552817 MCL1 0.39 7.67 0.38 1.75e-13 Melanoma; LIHC cis rs7208859 0.623 rs55724095 chr17:29153058 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.01 0.4 1.79e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs595982 0.559 rs73061632 chr19:49361663 G/A cg15549821 chr19:49342101 PLEKHA4 -0.7 -6.72 -0.34 7.41e-11 Red cell distribution width; LIHC cis rs7523273 0.606 rs2796271 chr1:207941927 A/G cg22525895 chr1:207977042 MIR29B2 0.63 10.22 0.48 1.38e-21 Schizophrenia; LIHC cis rs12142240 0.698 rs68012736 chr1:46839510 A/G cg00530320 chr1:46809349 NSUN4 0.54 5.77 0.3 1.76e-8 Menopause (age at onset); LIHC cis rs2075371 1.000 rs2241336 chr7:133979578 A/G cg20476274 chr7:133979776 SLC35B4 0.75 12.78 0.57 7.96e-31 Mean platelet volume; LIHC cis rs9814567 1.000 rs9826496 chr3:134224437 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.26 -0.55 6.69e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs769267 0.930 rs751856 chr19:19602945 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.34 0.32 7.45e-10 Tonsillectomy; LIHC trans rs9929218 0.953 rs3114411 chr16:68734591 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.61 8.5 0.42 5.93e-16 Colorectal cancer; LIHC cis rs1559088 0.847 rs6510348 chr19:33601946 G/A cg17764715 chr19:33622953 WDR88 0.45 6.5 0.33 2.78e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs240764 0.658 rs7451736 chr6:101189901 C/T cg09795085 chr6:101329169 ASCC3 -0.46 -6.69 -0.34 9.07e-11 Neuroticism; LIHC trans rs800082 0.734 rs1726538 chr3:144248888 A/G cg24215973 chr2:240111563 HDAC4 0.45 6.45 0.33 3.73e-10 Smoking behavior; LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg09455208 chr3:40491958 NA -0.37 -7.56 -0.38 3.86e-13 Renal cell carcinoma; LIHC cis rs1975974 0.872 rs66502681 chr17:21722119 T/A cg18423549 chr17:21743878 NA -0.47 -6.17 -0.32 1.97e-9 Psoriasis; LIHC cis rs2073300 1.000 rs112057098 chr20:23448901 C/T cg12062639 chr20:23401060 NAPB 0.81 9.62 0.46 1.56e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs62103177 0.636 rs9958792 chr18:77627876 T/C cg05926928 chr17:57297772 GDPD1 -0.47 -6.16 -0.32 2.07e-9 Opioid sensitivity; LIHC cis rs950169 0.922 rs6603022 chr15:84830170 T/C cg03959625 chr15:84868606 LOC388152 -0.45 -6.53 -0.33 2.4e-10 Schizophrenia; LIHC cis rs317689 0.918 rs581911 chr12:69738293 C/T cg19645103 chr12:69753606 YEATS4 -0.43 -5.82 -0.3 1.39e-8 Response to diuretic therapy; LIHC cis rs7116495 0.609 rs2276384 chr11:71701523 A/G cg10381502 chr11:71823885 C11orf51 0.91 8.04 0.4 1.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs79387448 0.745 rs1880000 chr2:103099953 T/C cg09003973 chr2:102972529 NA 0.83 7.19 0.36 3.98e-12 Gut microbiota (bacterial taxa); LIHC cis rs765787 0.530 rs2413785 chr15:45530381 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.05e-13 Uric acid levels; LIHC cis rs9393692 0.905 rs2393592 chr6:26285560 A/G cg05868516 chr6:26286170 HIST1H4H 0.42 6.29 0.32 9.74e-10 Educational attainment; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.76 0.8 2.86e-78 Prudent dietary pattern; LIHC cis rs7937682 0.889 rs2850247 chr11:111637202 C/A cg09085632 chr11:111637200 PPP2R1B 1.26 22.35 0.77 7.48e-69 Primary sclerosing cholangitis; LIHC cis rs7772486 0.790 rs2256998 chr6:146207657 A/C cg23711669 chr6:146136114 FBXO30 0.64 11.1 0.51 1.21e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs7552404 0.961 rs1061337 chr1:76227022 A/G cg10523679 chr1:76189770 ACADM 0.64 8.57 0.42 3.62e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg06420487 chr17:61919686 SMARCD2 0.45 6.21 0.32 1.56e-9 Height; LIHC cis rs4975616 0.869 rs467095 chr5:1336221 T/C cg07493874 chr5:1342172 CLPTM1L -0.68 -10.95 -0.51 4.02e-24 Lung cancer; LIHC cis rs546131 0.928 rs547504 chr11:34847225 G/T cg11058730 chr11:34937778 PDHX;APIP 0.61 9.14 0.44 5.69e-18 Lung disease severity in cystic fibrosis; LIHC cis rs1801251 0.963 rs13424351 chr2:233573629 A/G cg25237894 chr2:233734115 C2orf82 0.52 9.85 0.47 2.66e-20 Coronary artery disease; LIHC cis rs4919087 0.620 rs793515 chr10:98988469 A/C cg25902810 chr10:99078978 FRAT1 -0.56 -6.29 -0.32 9.75e-10 Monocyte count; LIHC cis rs8067354 0.574 rs9789060 chr17:58018570 A/G cg13753209 chr17:57696993 CLTC 0.71 10.58 0.5 7.79e-23 Hemoglobin concentration; LIHC cis rs763121 0.925 rs17032 chr22:39130843 C/G cg14440974 chr22:39074834 NA -0.35 -6.02 -0.31 4.46e-9 Menopause (age at onset); LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg00149659 chr3:10157352 C3orf10 0.49 5.82 0.3 1.39e-8 Alzheimer's disease; LIHC cis rs523522 0.962 rs7488320 chr12:120981630 G/T cg12219531 chr12:120966889 COQ5 0.68 13.4 0.59 3.38e-33 High light scatter reticulocyte count; LIHC cis rs4819052 0.724 rs1304487 chr21:46657283 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.46 -6.76 -0.34 5.84e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs35306767 0.951 rs12777021 chr10:967270 T/C cg26597838 chr10:835615 NA 1.16 12.47 0.56 1.09e-29 Eosinophil percentage of granulocytes; LIHC cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg23172400 chr8:95962367 TP53INP1 0.35 7.62 0.38 2.52e-13 Type 2 diabetes; LIHC cis rs8180040 0.676 rs66564457 chr3:47020072 G/A cg27129171 chr3:47204927 SETD2 0.62 10.68 0.5 3.62e-23 Colorectal cancer; LIHC cis rs858239 0.601 rs15775 chr7:23164701 C/T cg23682824 chr7:23144976 KLHL7 0.45 6.73 0.34 7.1e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs9682041 0.932 rs6782252 chr3:170133639 C/T cg11886554 chr3:170076028 SKIL 0.91 6.66 0.34 1.09e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs8017423 0.967 rs2149655 chr14:90707246 T/C cg14092571 chr14:90743983 NA -0.37 -5.88 -0.3 9.66e-9 Mortality in heart failure; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg23888375 chr2:203776317 ALS2CR8;WDR12 -0.35 -6.13 -0.31 2.39e-9 Bilirubin levels; LIHC cis rs7086627 0.515 rs1870147 chr10:82212541 A/T cg01528321 chr10:82214614 TSPAN14 0.52 7.39 0.37 1.13e-12 Post bronchodilator FEV1; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.48 0.38 6.21e-13 Prudent dietary pattern; LIHC cis rs7940866 0.874 rs10894306 chr11:130873882 A/C cg12179176 chr11:130786555 SNX19 0.56 7.87 0.39 4.72e-14 Schizophrenia; LIHC cis rs2153535 0.580 rs9505454 chr6:8478532 T/G cg21535247 chr6:8435926 SLC35B3 0.59 7.82 0.39 6.53e-14 Motion sickness; LIHC cis rs1152591 1.000 rs2738413 chr14:64679960 A/G cg23250157 chr14:64679961 SYNE2 0.45 6.69 0.34 9.09e-11 Atrial fibrillation; LIHC cis rs2243480 0.522 rs1638736 chr7:66092308 A/T cg18252515 chr7:66147081 NA -1.32 -15.69 -0.65 3.57e-42 Diabetic kidney disease; LIHC cis rs807669 0.903 rs807667 chr22:19161327 A/G cg02655711 chr22:19163373 SLC25A1 -0.74 -11.45 -0.53 6.21e-26 Metabolite levels; LIHC cis rs2274273 0.901 rs112870553 chr14:55790062 T/G cg01864836 chr14:55583639 NA -0.4 -7.45 -0.37 7.51e-13 Protein biomarker; LIHC cis rs6840360 1.000 rs2303866 chr4:152640387 C/T cg22705602 chr4:152727874 NA -0.36 -7.52 -0.38 4.76e-13 Intelligence (multi-trait analysis); LIHC cis rs4409675 0.576 rs10751725 chr1:28216191 A/C cg23691781 chr1:28212827 C1orf38 -0.31 -7.56 -0.38 3.82e-13 Corneal astigmatism; LIHC cis rs36051895 0.664 rs17425819 chr9:5114773 C/T cg02405213 chr9:5042618 JAK2 -0.65 -11.3 -0.52 2.29e-25 Pediatric autoimmune diseases; LIHC cis rs7551222 0.752 rs12125533 chr1:204529302 A/C cg20240347 chr1:204465584 NA -0.35 -7.51 -0.38 5.23e-13 Schizophrenia; LIHC trans rs11098499 0.754 rs10212775 chr4:120239244 G/C cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg00149659 chr3:10157352 C3orf10 0.63 6.87 0.35 2.99e-11 Alzheimer's disease; LIHC cis rs28595532 0.546 rs17516389 chr4:119239267 T/C cg21605333 chr4:119757512 SEC24D 0.79 6.71 0.34 8.15e-11 Cannabis dependence symptom count; LIHC cis rs9811920 0.638 rs796977 chr3:99549723 T/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.13 0.36 6.18e-12 Axial length; LIHC cis rs2075371 1.000 rs2544218 chr7:133992315 C/A cg20476274 chr7:133979776 SLC35B4 0.75 12.66 0.56 2.2e-30 Mean platelet volume; LIHC cis rs7959452 0.536 rs4761237 chr12:69776461 C/G cg14784868 chr12:69753453 YEATS4 0.94 20.42 0.74 3.62e-61 Blood protein levels; LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.73 10.63 0.5 5.22e-23 Lymphocyte counts; LIHC cis rs7927592 0.956 rs10896334 chr11:68281494 C/T cg20283391 chr11:68216788 NA -0.51 -7.6 -0.38 2.86e-13 Total body bone mineral density; LIHC cis rs826838 0.967 rs1719854 chr12:39127707 G/A cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs7903847 0.596 rs869967 chr10:99147975 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9430161 0.645 rs6675082 chr1:11033797 T/C cg02454025 chr1:11042201 C1orf127 0.96 18.1 0.7 7.59e-52 Ewing sarcoma; LIHC cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs910316 0.935 rs175076 chr14:75505486 A/G cg11812906 chr14:75593930 NEK9 -0.74 -14.5 -0.62 1.87e-37 Height; LIHC cis rs9952991 0.941 rs8096138 chr18:12808140 C/G cg23598886 chr18:12777645 NA -0.43 -5.77 -0.3 1.81e-8 Inflammatory skin disease; LIHC cis rs72615157 0.634 rs74742883 chr7:99785765 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.55 5.73 0.3 2.19e-8 Lung function (FEV1/FVC); LIHC cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9309473 0.898 rs6546861 chr2:73849861 C/T cg20560298 chr2:73613845 ALMS1 -0.53 -6.65 -0.34 1.13e-10 Metabolite levels; LIHC cis rs2204008 0.743 rs2127952 chr12:37995364 G/T cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC cis rs8192917 0.832 rs10873219 chr14:25101706 A/C cg08766149 chr14:25103301 GZMB -0.33 -7.11 -0.36 6.68e-12 Vitiligo; LIHC cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg13409248 chr3:40428643 ENTPD3 -0.41 -7.01 -0.35 1.3e-11 Renal cell carcinoma; LIHC cis rs709400 0.894 rs56017123 chr14:104075277 G/A cg26031613 chr14:104095156 KLC1 1.15 15.1 0.63 8.1e-40 Body mass index; LIHC cis rs4665809 0.680 rs3955310 chr2:26290828 T/G cg27170947 chr2:26402098 FAM59B -0.62 -7.76 -0.39 1.02e-13 Gut microbiome composition (summer); LIHC cis rs4423214 0.840 rs2017686 chr11:71187061 C/G cg05163923 chr11:71159392 DHCR7 -0.6 -7.9 -0.39 3.79e-14 Vitamin D levels; LIHC cis rs67478160 0.643 rs11628332 chr14:104241141 C/T cg24130564 chr14:104152367 KLC1 -0.36 -6.12 -0.31 2.61e-9 Schizophrenia; LIHC cis rs826838 0.967 rs1684411 chr12:39128494 C/T cg26384229 chr12:38710491 ALG10B -0.6 -8.66 -0.42 1.92e-16 Heart rate; LIHC cis rs7829975 0.742 rs1533059 chr8:8684953 A/G cg06636001 chr8:8085503 FLJ10661 -0.43 -6.98 -0.35 1.53e-11 Mood instability; LIHC cis rs6684514 0.961 rs11264469 chr1:156276746 A/G cg16558208 chr1:156270281 VHLL 0.54 10.14 0.48 2.7e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9993613 1.000 rs4694502 chr4:73496157 G/A cg15102770 chr4:73434591 ADAMTS3 -0.38 -5.83 -0.3 1.3e-8 Hip circumference adjusted for BMI;Height; LIHC cis rs9790314 1.000 rs336591 chr3:161078080 A/G cg03342759 chr3:160939853 NMD3 -0.67 -8.05 -0.4 1.35e-14 Morning vs. evening chronotype; LIHC cis rs2404602 0.552 rs11072613 chr15:76961526 A/C cg03037974 chr15:76606532 NA -0.47 -7.23 -0.36 3.17e-12 Blood metabolite levels; LIHC cis rs4764487 0.735 rs3181301 chr12:6345784 G/T cg08284733 chr12:6341482 CD9 0.35 6.01 0.31 4.69e-9 Mean platelet volume; LIHC cis rs10504229 0.679 rs6474100 chr8:58031161 G/A cg02290350 chr8:58132656 NA 0.31 7.17 0.36 4.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs7552404 1.000 rs2133134 chr1:76179587 G/A cg03433033 chr1:76189801 ACADM 0.67 9.32 0.45 1.51e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs858239 0.600 rs28646184 chr7:23139595 T/C cg23682824 chr7:23144976 KLHL7 0.45 6.72 0.34 7.72e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2243480 1.000 rs778729 chr7:65824419 T/C cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC trans rs11098499 0.697 rs10016448 chr4:120298845 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg23758822 chr17:41437982 NA 0.95 17.65 0.69 4.96e-50 Menopause (age at onset); LIHC cis rs4631830 0.720 rs7090326 chr10:51503375 A/T cg16070123 chr10:51489643 NA -0.37 -5.89 -0.3 9.03e-9 Prostate-specific antigen levels; LIHC cis rs754466 0.580 rs11002289 chr10:79532580 G/A cg17075019 chr10:79541650 NA -0.79 -12.07 -0.55 3.59e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7914558 1.000 rs4917994 chr10:104811699 C/T cg15744005 chr10:104629667 AS3MT -0.39 -8.86 -0.43 4.32e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8067545 0.750 rs9944451 chr17:20001316 T/C cg13482628 chr17:19912719 NA 0.49 7.98 0.4 2.24e-14 Schizophrenia; LIHC cis rs9916302 0.706 rs8067511 chr17:37611352 C/T cg07936489 chr17:37558343 FBXL20 -0.87 -12.27 -0.55 6.3e-29 Glomerular filtration rate (creatinine); LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg10150615 chr22:24372951 LOC391322 -0.52 -7.55 -0.38 4.04e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.93 0.31 7.39e-9 Tonsillectomy; LIHC cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg12756686 chr19:29218302 NA 0.44 7.19 0.36 4.16e-12 Methadone dose in opioid dependence; LIHC cis rs10949834 0.504 rs12539781 chr7:73568425 C/T cg07137043 chr7:73588983 EIF4H -0.67 -7.91 -0.39 3.62e-14 Verbal memory performance (residualized delayed recall change); LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.93 0.57 2.1e-31 Prudent dietary pattern; LIHC cis rs35306767 0.761 rs11253540 chr10:1011958 C/T cg20503657 chr10:835505 NA -0.87 -8.27 -0.41 3.09e-15 Eosinophil percentage of granulocytes; LIHC cis rs9309473 1.000 rs10207220 chr2:73785046 G/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs1801251 0.752 rs2592126 chr2:233751377 A/G cg08000102 chr2:233561755 GIGYF2 -0.73 -10.62 -0.5 5.68e-23 Coronary artery disease; LIHC trans rs3808502 0.527 rs2736374 chr8:11113828 A/G cg00705908 chr8:17942569 ASAH1 0.46 6.35 0.32 6.91e-10 Neuroticism; LIHC cis rs17384381 0.861 rs34561661 chr1:85777250 C/T cg16011679 chr1:85725395 C1orf52 0.88 9.25 0.45 2.45e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg08067268 chr2:26466485 HADHB;HADHA -0.43 -6.44 -0.33 4.03e-10 Gut microbiome composition (summer); LIHC cis rs72781680 0.948 rs113530757 chr2:24142500 G/A cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg21280719 chr6:42927975 GNMT -0.36 -7.88 -0.39 4.27e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg18538332 chr22:24372958 LOC391322 -0.72 -11.21 -0.52 4.9e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg22974920 chr21:40686053 BRWD1 -0.4 -5.78 -0.3 1.66e-8 Cognitive function; LIHC cis rs1008375 0.931 rs10008337 chr4:17593849 G/C cg16339924 chr4:17578868 LAP3 0.46 6.43 0.33 4.32e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9640161 0.659 rs11974980 chr7:150009838 C/T cg17279839 chr7:150038598 RARRES2 0.49 10.02 0.48 6.78e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs3796352 1.000 rs35720014 chr3:52982110 A/C cg07884673 chr3:53033167 SFMBT1 0.89 6.49 0.33 3.1e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2304069 0.913 rs9324637 chr5:149390947 T/C cg22760475 chr5:149380129 HMGXB3;TIGD6 0.97 12.61 0.56 3.25e-30 HIV-1 control; LIHC cis rs55665837 0.523 rs10832301 chr11:14788964 G/A cg25251204 chr11:14927456 NA 0.41 5.79 0.3 1.56e-8 Vitamin D levels; LIHC trans rs12478296 0.901 rs56318767 chr2:243046591 T/A cg01596870 chr19:55963115 NA -0.64 -8.49 -0.42 6.49e-16 Obesity-related traits; LIHC cis rs739401 0.611 rs2071104 chr11:3036933 G/T cg05729581 chr11:3078854 CARS -0.42 -5.81 -0.3 1.42e-8 Longevity; LIHC cis rs7937890 0.559 rs2575836 chr11:14497864 T/G cg02886208 chr11:14281011 SPON1 -0.44 -6.15 -0.32 2.17e-9 Mitochondrial DNA levels; LIHC cis rs709400 1.000 rs10135248 chr14:104122310 T/C cg26031613 chr14:104095156 KLC1 0.99 13.74 0.6 1.57e-34 Body mass index; LIHC cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.46 6.6 0.34 1.61e-10 Bipolar disorder; LIHC cis rs523522 1.000 rs1563333 chr12:120934407 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.98 0.54 7.42e-28 High light scatter reticulocyte count; LIHC cis rs6701037 0.714 rs2285219 chr1:175130983 A/T cg17845761 chr1:175162550 KIAA0040 -0.43 -7.18 -0.36 4.36e-12 Alcohol dependence; LIHC cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.72 -12.53 -0.56 6.93e-30 Colorectal cancer; LIHC cis rs9467773 1.000 rs6910899 chr6:26524339 A/G cg09904177 chr6:26538194 HMGN4 0.67 14.0 0.6 1.66e-35 Intelligence (multi-trait analysis); LIHC cis rs55665837 0.701 rs11023265 chr11:14616038 C/T cg16394018 chr11:14927549 NA 0.41 5.85 0.3 1.12e-8 Vitamin D levels; LIHC cis rs2455799 0.613 rs1345157 chr3:15895581 C/G cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.96e-13 Mean platelet volume; LIHC trans rs72766638 0.895 rs72766630 chr9:136926791 G/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.57 -6.38 -0.33 5.67e-10 Mosquito bite size; LIHC cis rs2479724 0.905 rs2251274 chr6:41839438 T/G cg17623882 chr6:41773611 USP49 -0.56 -8.79 -0.43 7.45e-17 Menarche (age at onset); LIHC cis rs11971779 0.616 rs7784192 chr7:139039649 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs1355223 0.583 rs2941041 chr11:34874734 A/C cg24088639 chr11:34937564 PDHX;APIP -0.38 -6.0 -0.31 5.03e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs35306767 0.903 rs11253462 chr10:889323 T/G cg26597838 chr10:835615 NA 1.11 13.81 0.6 9.05e-35 Eosinophil percentage of granulocytes; LIHC cis rs7223966 0.960 rs2854222 chr17:61939015 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 7.29 0.37 2.18e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1387259 0.790 rs2732445 chr12:48645533 C/T cg21466736 chr12:48725269 NA -0.71 -10.74 -0.5 2.25e-23 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg18252515 chr7:66147081 NA -1.23 -16.1 -0.66 8.28e-44 Diabetic kidney disease; LIHC trans rs1005277 0.522 rs289649 chr10:37975384 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.47 -0.33 3.39e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6430585 0.528 rs6430594 chr2:136719173 C/T cg07169764 chr2:136633963 MCM6 -1.28 -21.05 -0.75 1.06e-63 Corneal structure; LIHC cis rs4934494 0.768 rs2094214 chr10:91409381 G/A cg19698084 chr10:91461284 KIF20B -0.49 -6.5 -0.33 2.91e-10 Red blood cell count; LIHC cis rs12824058 0.831 rs11608407 chr12:130805869 G/A cg24229701 chr12:130821962 PIWIL1 0.43 6.29 0.32 9.44e-10 Menopause (age at onset); LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -6.97 -0.35 1.59e-11 Total body bone mineral density; LIHC cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg12756686 chr19:29218302 NA 0.44 6.81 0.35 4.5e-11 Methadone dose in opioid dependence; LIHC trans rs11088226 0.758 rs2833864 chr21:33888393 A/C cg09050820 chr6:167586206 TCP10L2 0.49 6.64 0.34 1.23e-10 Gastritis; LIHC cis rs1865721 0.771 rs8093397 chr18:73136217 C/G cg26385618 chr18:73139727 C18orf62 -0.31 -8.53 -0.42 4.8e-16 Intelligence; LIHC cis rs10791097 0.694 rs2236711 chr11:130739284 G/A cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs16828019 0.852 rs12044539 chr1:41661732 A/C cg03962019 chr1:41807865 NA 0.52 7.6 0.38 2.92e-13 Intelligence (multi-trait analysis); LIHC cis rs492146 0.740 rs1032418 chr6:52834957 A/T cg24393602 chr6:52860404 GSTA4 0.43 6.21 0.32 1.57e-9 Epilepsy (remission after treatment); LIHC cis rs1707322 1.000 rs6687301 chr1:46382852 T/C cg03146154 chr1:46216737 IPP 0.47 7.62 0.38 2.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7715806 0.517 rs253392 chr5:74928883 G/T cg19683494 chr5:74908142 NA -0.54 -6.98 -0.35 1.58e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9896052 0.608 rs61264861 chr17:73459278 T/C cg25649188 chr17:73499917 CASKIN2 0.43 6.65 0.34 1.17e-10 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg18306943 chr3:40428807 ENTPD3 0.35 5.92 0.31 7.71e-9 Renal cell carcinoma; LIHC cis rs7301016 0.802 rs11613011 chr12:63023078 T/C cg11441379 chr12:63026424 NA 0.6 6.18 0.32 1.87e-9 IgG glycosylation; LIHC cis rs911119 1.000 rs13041070 chr20:23614261 G/A cg16589663 chr20:23618590 CST3 0.75 7.66 0.38 1.98e-13 Chronic kidney disease; LIHC cis rs4689592 0.503 rs2292461 chr4:7058473 C/T cg02503808 chr4:7069936 GRPEL1 0.66 9.39 0.45 8.9e-19 Monocyte percentage of white cells; LIHC cis rs9807989 0.507 rs1420105 chr2:103035119 A/G cg03938978 chr2:103052716 IL18RAP 0.31 5.95 0.31 6.55e-9 Asthma; LIHC cis rs7903847 0.642 rs7903562 chr10:99154782 T/C cg20016023 chr10:99160130 RRP12 -0.41 -6.62 -0.34 1.4e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs904251 0.772 rs1224127 chr6:37417556 G/A cg01843034 chr6:37503916 NA -0.39 -6.37 -0.33 6.15e-10 Cognitive performance; LIHC cis rs6831352 0.879 rs56272995 chr4:100060882 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg16405210 chr4:1374714 KIAA1530 -0.9 -14.99 -0.63 2.07e-39 Longevity; LIHC cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.1 -16.52 -0.67 1.7e-45 Gut microbiome composition (summer); LIHC cis rs2282802 0.685 rs12717951 chr5:139589309 A/G cg26211634 chr5:139558579 C5orf32 0.38 5.92 0.3 7.74e-9 Intelligence (multi-trait analysis); LIHC cis rs7635838 0.892 rs9874535 chr3:11463730 A/G cg00170343 chr3:11313890 ATG7 0.45 7.01 0.35 1.3e-11 HDL cholesterol; LIHC cis rs8180040 0.966 rs11925823 chr3:47443065 C/G cg16586182 chr3:47516702 SCAP -0.58 -10.97 -0.51 3.34e-24 Colorectal cancer; LIHC cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg11644478 chr21:40555479 PSMG1 -0.38 -5.85 -0.3 1.12e-8 Cognitive function; LIHC cis rs11676348 0.846 rs4674259 chr2:218991005 C/T cg00012203 chr2:219082015 ARPC2 -0.55 -7.71 -0.38 1.41e-13 Ulcerative colitis; LIHC cis rs9916302 0.861 rs9903363 chr17:37499604 C/G cg00129232 chr17:37814104 STARD3 0.38 6.08 0.31 3.27e-9 Glomerular filtration rate (creatinine); LIHC cis rs1538970 0.962 rs2153607 chr1:45813820 G/A cg05343316 chr1:45956843 TESK2 0.54 8.08 0.4 1.11e-14 Platelet count; LIHC cis rs7618501 0.602 rs10049087 chr3:50123417 A/G cg24110177 chr3:50126178 RBM5 0.54 8.71 0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs8062405 1.000 rs62036657 chr16:28844365 G/A cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8078723 1.000 rs8078723 chr17:38166879 A/G cg17467752 chr17:38218738 THRA 0.77 14.24 0.61 1.85e-36 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs881375 0.967 rs10435843 chr9:123668033 A/G cg14580859 chr9:123691850 NA 0.39 6.83 0.35 3.96e-11 Rheumatoid arthritis; LIHC cis rs7903847 0.642 rs9887991 chr10:99159634 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.68 -0.34 9.45e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs6502050 0.835 rs8067875 chr17:80092778 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.59e-9 Life satisfaction; LIHC cis rs2153535 0.580 rs2327051 chr6:8441150 A/G cg23788917 chr6:8435910 SLC35B3 -0.57 -8.3 -0.41 2.51e-15 Motion sickness; LIHC cis rs5769765 0.954 rs5770707 chr22:50244533 G/A cg26441486 chr22:50317300 CRELD2 -0.36 -6.51 -0.33 2.6e-10 Schizophrenia; LIHC cis rs1799949 1.000 rs2298862 chr17:41176688 T/C cg25072359 chr17:41440525 NA 0.37 5.95 0.31 6.7e-9 Menopause (age at onset); LIHC cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg00475322 chr7:917719 C7orf20 0.42 7.12 0.36 6.33e-12 Perceived unattractiveness to mosquitoes; LIHC cis rs933688 1.000 rs332529 chr5:90789470 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.81 15.91 0.65 4.81e-43 Smoking behavior; LIHC cis rs36051895 0.593 rs12682970 chr9:5168137 C/T cg02405213 chr9:5042618 JAK2 -0.68 -10.36 -0.49 4.58e-22 Pediatric autoimmune diseases; LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg24209194 chr3:40518798 ZNF619 -0.63 -9.6 -0.46 1.82e-19 Renal cell carcinoma; LIHC cis rs1559088 0.576 rs4805852 chr19:33609441 C/T cg03563238 chr19:33554763 RHPN2 -0.31 -5.9 -0.3 8.85e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7914558 1.000 rs67908413 chr10:104764989 T/C cg15744005 chr10:104629667 AS3MT -0.36 -8.05 -0.4 1.39e-14 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs116095464 0.558 rs10036253 chr5:238519 A/C cg22496380 chr5:211416 CCDC127 -1.03 -10.71 -0.5 2.89e-23 Breast cancer; LIHC cis rs1113500 0.933 rs4593854 chr1:108638519 A/G cg06207961 chr1:108661230 NA 0.39 7.63 0.38 2.34e-13 Growth-regulated protein alpha levels; LIHC cis rs7474896 0.537 rs2472149 chr10:38262196 A/C cg25427524 chr10:38739819 LOC399744 0.46 6.02 0.31 4.43e-9 Obesity (extreme); LIHC cis rs8072100 0.934 rs9905583 chr17:45741016 C/T cg08085267 chr17:45401833 C17orf57 -0.57 -8.33 -0.41 2.02e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10861342 1.000 rs11112397 chr12:105568381 T/C cg23923672 chr12:105501055 KIAA1033 0.69 8.59 0.42 3.19e-16 IgG glycosylation; LIHC cis rs4759375 0.915 rs11503021 chr12:123844558 C/T cg00376283 chr12:123451042 ABCB9 0.49 6.31 0.32 8.57e-10 HDL cholesterol; LIHC cis rs4788570 0.513 rs2113223 chr16:71607915 A/G cg06353428 chr16:71660113 MARVELD3 -1.25 -11.09 -0.51 1.25e-24 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.647 rs11072631 chr15:77132909 T/C cg03037974 chr15:76606532 NA -0.59 -9.92 -0.47 1.49e-20 Blood metabolite levels; LIHC cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg25072359 chr17:41440525 NA 0.37 5.83 0.3 1.3e-8 Menopause (age at onset); LIHC cis rs9300255 0.537 rs1618679 chr12:123650714 A/G cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs1552244 0.554 rs34391585 chr3:9999208 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -7.77 -0.39 9.19e-14 Alzheimer's disease; LIHC cis rs7786877 0.500 rs2272572 chr7:100285888 C/T cg20848291 chr7:100343083 ZAN -0.46 -6.52 -0.33 2.54e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg10883421 chr6:151773342 RMND1;C6orf211 -0.71 -11.37 -0.52 1.24e-25 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00049502 chr12:112280971 C12orf47;MAPKAPK5 0.41 6.11 0.31 2.74e-9 Pancreatic cancer; LIHC cis rs1552244 0.572 rs68013239 chr3:10165711 G/T cg00149659 chr3:10157352 C3orf10 0.9 8.64 0.42 2.21e-16 Alzheimer's disease; LIHC cis rs12478296 0.901 rs7603560 chr2:243043256 C/T cg05760424 chr2:242988095 NA -0.51 -6.79 -0.34 4.97e-11 Obesity-related traits; LIHC cis rs12477438 0.501 rs12619780 chr2:99707307 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.61 11.19 0.52 5.72e-25 Chronic sinus infection; LIHC cis rs1005277 0.602 rs1740743 chr10:38519222 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs4716602 0.586 rs13224457 chr7:156161005 G/T cg16983916 chr7:156159713 NA -0.32 -5.72 -0.3 2.39e-8 Anti-saccade response; LIHC cis rs61990749 0.686 rs11159288 chr14:78216972 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.16 0.48 2.37e-21 Fibroblast growth factor basic levels; LIHC cis rs769267 0.965 rs1469712 chr19:19528821 C/A cg03709012 chr19:19516395 GATAD2A 1.02 18.24 0.7 2.09e-52 Tonsillectomy; LIHC cis rs66569888 0.789 rs66826026 chr2:106732879 C/T cg00318621 chr2:106887213 NA -0.58 -5.92 -0.3 7.75e-9 Facial morphology (factor 23); LIHC cis rs703842 1.000 rs11172342 chr12:58187758 G/T cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.3 0.61 1.07e-36 Multiple sclerosis; LIHC cis rs11583043 1.000 rs2391573 chr1:101489698 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.82 0.3 1.39e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9392556 0.600 rs611500 chr6:4126763 C/G cg10424681 chr6:4079350 C6orf201;C6orf146 0.24 5.76 0.3 1.84e-8 Blood metabolite levels; LIHC cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg19539972 chr4:7069911 GRPEL1 0.68 9.97 0.47 9.8e-21 Monocyte percentage of white cells; LIHC cis rs1577917 0.771 rs2475790 chr6:86368068 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.58 -0.56 4.43e-30 Response to antipsychotic treatment; LIHC cis rs2455799 0.634 rs1345160 chr3:15862026 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.88e-13 Mean platelet volume; LIHC cis rs35306767 0.903 rs10508208 chr10:910983 C/T cg26597838 chr10:835615 NA 1.1 13.54 0.59 9.53e-34 Eosinophil percentage of granulocytes; LIHC cis rs2239547 0.618 rs4687663 chr3:52870618 T/A cg11645453 chr3:52864694 ITIH4 0.35 9.12 0.44 6.64e-18 Schizophrenia; LIHC cis rs8053891 0.625 rs12921355 chr16:72014687 T/A cg01557791 chr16:72042693 DHODH -0.51 -7.41 -0.37 9.99e-13 Coronary artery disease; LIHC cis rs1003719 0.788 rs9975168 chr21:38450557 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.78 -12.22 -0.55 9.4e-29 Eye color traits; LIHC cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.38 5.72 0.3 2.29e-8 Schizophrenia; LIHC cis rs7715806 0.500 rs2291630 chr5:75013356 G/A cg00601450 chr5:74908170 NA 0.58 7.1 0.36 7.09e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9322817 1.000 rs9322817 chr6:105232233 A/C cg02098413 chr6:105308735 HACE1 -0.37 -6.06 -0.31 3.67e-9 Thyroid stimulating hormone; LIHC cis rs666930 0.519 rs483180 chr1:120267505 C/G cg19096424 chr1:120255104 PHGDH -0.93 -11.99 -0.54 6.86e-28 Breast cancer; LIHC cis rs9430161 0.645 rs12081186 chr1:11034195 T/C cg02454025 chr1:11042201 C1orf127 0.96 18.34 0.7 8.49e-53 Ewing sarcoma; LIHC cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg10755058 chr3:40428713 ENTPD3 0.39 6.6 0.34 1.61e-10 Renal cell carcinoma; LIHC cis rs8049040 0.967 rs7203200 chr16:71465613 T/G cg06353428 chr16:71660113 MARVELD3 -0.56 -5.88 -0.3 9.8e-9 Blood protein levels; LIHC cis rs1670533 1.000 rs1670534 chr4:1087265 T/C cg27284194 chr4:1044797 NA 0.61 8.99 0.44 1.72e-17 Recombination rate (females); LIHC trans rs2749592 0.550 rs9733309 chr10:37882405 G/A cg23533926 chr12:111358616 MYL2 0.31 6.05 0.31 3.88e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs722599 0.683 rs2302834 chr14:75279395 T/A cg08847533 chr14:75593920 NEK9 0.53 8.17 0.4 6.15e-15 IgG glycosylation; LIHC cis rs6596100 0.538 rs55976357 chr5:132194565 C/A cg02081065 chr5:132209139 LEAP2 0.29 6.3 0.32 9.39e-10 Breast cancer; LIHC cis rs11764590 0.694 rs10235664 chr7:2086814 T/C cg23422044 chr7:1970798 MAD1L1 -0.5 -7.79 -0.39 7.87e-14 Neuroticism; LIHC cis rs6952808 0.531 rs3778991 chr7:2172455 G/A cg21782813 chr7:2030301 MAD1L1 0.37 6.24 0.32 1.29e-9 Bipolar disorder and schizophrenia; LIHC cis rs2236918 0.932 rs1635517 chr1:242012033 A/G cg17736920 chr1:242011382 EXO1 -0.62 -8.97 -0.44 2.02e-17 Menopause (age at onset); LIHC cis rs6088580 0.634 rs6087580 chr20:32992592 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.33 -0.58 6.15e-33 Glomerular filtration rate (creatinine); LIHC cis rs10751667 0.600 rs7950955 chr11:1011490 G/A ch.11.42038R chr11:967971 AP2A2 0.59 10.83 0.51 1.03e-23 Alzheimer's disease (late onset); LIHC cis rs10870270 0.564 rs45519634 chr10:133782616 C/T cg08754478 chr10:133766260 PPP2R2D -0.61 -5.92 -0.31 7.67e-9 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7412746 0.611 rs1889740 chr1:150799755 C/T cg17724175 chr1:150552817 MCL1 0.43 8.68 0.42 1.61e-16 Melanoma; LIHC cis rs1552244 0.882 rs35056669 chr3:10014171 C/T cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs55823223 0.564 rs936391 chr17:73847799 A/G cg08125733 chr17:73851984 WBP2 -0.81 -12.55 -0.56 5.48e-30 Psoriasis; LIHC cis rs722599 0.748 rs11623342 chr14:75347937 A/C cg11812906 chr14:75593930 NEK9 -0.45 -7.0 -0.35 1.33e-11 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03480535 chr4:87856849 AFF1 0.47 7.56 0.38 3.62e-13 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26398791 chr1:38455867 SF3A3 0.42 6.14 0.32 2.28e-9 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12346351 chr4:152330392 FAM160A1 0.49 7.34 0.37 1.59e-12 Pancreatic cancer; LIHC cis rs6089584 0.566 rs11699442 chr20:60623268 A/G cg06108461 chr20:60628389 TAF4 -0.65 -9.14 -0.44 5.74e-18 Body mass index; LIHC cis rs1865760 0.566 rs9358904 chr6:26068566 C/T cg18357526 chr6:26021779 HIST1H4A 0.44 6.53 0.33 2.32e-10 Height; LIHC cis rs7659604 0.539 rs7699776 chr4:122753885 A/G cg19748678 chr4:122722346 EXOSC9 0.67 11.13 0.52 9.19e-25 Type 2 diabetes; LIHC cis rs10927875 0.632 rs4661666 chr1:16162471 C/A cg07117364 chr1:16154769 NA -0.39 -7.05 -0.36 1.02e-11 Dilated cardiomyopathy; LIHC cis rs2836950 0.545 rs4818001 chr21:40575088 T/C cg06238570 chr21:40685208 BRWD1 -0.44 -7.17 -0.36 4.57e-12 Menarche (age at onset); LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg23416307 chr4:858299 GAK 0.62 6.31 0.32 8.86e-10 Mean platelet volume; LIHC cis rs7582720 1.000 rs1541853 chr2:203835177 A/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4727027 0.933 rs12540094 chr7:148847178 A/G cg23583168 chr7:148888333 NA 0.73 10.56 0.5 9.66e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs3020736 0.500 rs11090076 chr22:42514190 T/C cg04733989 chr22:42467013 NAGA -0.64 -9.17 -0.44 4.48e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs9911578 0.765 rs66954617 chr17:56999427 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg06212747 chr3:49208901 KLHDC8B 0.59 7.67 0.38 1.78e-13 Parkinson's disease; LIHC cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.954 rs6838814 chr4:120392443 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.77 0.47 4.61e-20 Corneal astigmatism; LIHC cis rs2153535 0.580 rs1335641 chr6:8487860 G/T cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs1707322 0.865 rs785501 chr1:46579611 C/T cg03146154 chr1:46216737 IPP -0.45 -7.22 -0.36 3.36e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs644799 0.965 rs602512 chr11:95561682 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs17711722 0.727 rs781151 chr7:65479878 T/C cg26939375 chr7:64535504 NA 0.46 6.79 0.34 5.01e-11 Calcium levels; LIHC cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg20607798 chr8:58055168 NA 0.49 6.3 0.32 9.41e-10 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.658 rs4895683 chr6:146113654 T/A cg23711669 chr6:146136114 FBXO30 -0.72 -12.99 -0.57 1.23e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs1046896 0.561 rs8076476 chr17:80861017 A/C cg02711726 chr17:80685570 FN3KRP -0.44 -8.04 -0.4 1.43e-14 Glycated hemoglobin levels; LIHC cis rs2836974 0.644 rs11088472 chr21:40699376 A/C cg17971929 chr21:40555470 PSMG1 -0.43 -6.42 -0.33 4.48e-10 Cognitive function; LIHC cis rs6545883 0.825 rs7578139 chr2:61564121 G/A cg15711740 chr2:61764176 XPO1 0.42 5.79 0.3 1.56e-8 Tuberculosis; LIHC cis rs6964587 0.620 rs7808587 chr7:91620096 G/A cg17063962 chr7:91808500 NA 0.63 11.33 0.52 1.78e-25 Breast cancer; LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs367615 0.918 rs17161895 chr5:108855831 T/G cg17395555 chr5:108820864 NA 0.34 7.11 0.36 6.99e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg02951883 chr7:2050386 MAD1L1 -0.62 -9.63 -0.46 1.41e-19 Bipolar disorder and schizophrenia; LIHC trans rs7246657 0.943 rs12709813 chr19:37844983 G/A cg10208301 chr11:6592745 DNHD1 0.48 6.96 0.35 1.71e-11 Coronary artery calcification; LIHC cis rs12022452 0.591 rs6672398 chr1:41002177 A/T cg25568243 chr1:40974465 DEM1 0.43 5.87 0.3 1.02e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs35883536 0.647 rs17411209 chr1:101046734 A/G cg14515779 chr1:101123966 NA 0.49 6.84 0.35 3.64e-11 Monocyte count; LIHC cis rs1023500 0.505 rs134901 chr22:42683520 C/T cg00645731 chr22:42541494 CYP2D7P1 0.38 6.47 0.33 3.31e-10 Schizophrenia; LIHC cis rs12701220 0.655 rs7784403 chr7:1153077 G/A cg04498913 chr7:1135747 C7orf50 0.45 7.1 0.36 7.45e-12 Bronchopulmonary dysplasia; LIHC cis rs782590 0.935 rs62165197 chr2:55801812 C/T cg03859395 chr2:55845619 SMEK2 0.86 15.43 0.64 4.04e-41 Metabolic syndrome; LIHC cis rs11676348 0.818 rs4674256 chr2:218987893 A/T cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.15 -0.32 2.21e-9 Ulcerative colitis; LIHC cis rs1707322 0.686 rs2991977 chr1:46053683 G/A cg24296786 chr1:45957014 TESK2 0.4 5.76 0.3 1.87e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9393692 0.645 rs4145910 chr6:26313305 T/C cg13736514 chr6:26305472 NA -0.4 -6.23 -0.32 1.36e-9 Educational attainment; LIHC trans rs8113308 0.810 rs11879040 chr19:52450109 A/C cg14959425 chr7:20447707 ITGB8 -0.47 -6.11 -0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs35306767 0.855 rs12781100 chr10:838636 C/T cg20503657 chr10:835505 NA 1.26 13.03 0.58 8.73e-32 Eosinophil percentage of granulocytes; LIHC cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.06 0.31 3.62e-9 Menopause (age at onset); LIHC cis rs5753037 0.653 rs131286 chr22:30158351 C/T cg01021169 chr22:30184971 ASCC2 -0.31 -5.72 -0.3 2.31e-8 Type 1 diabetes; LIHC cis rs7296418 0.961 rs4275659 chr12:123447928 C/T cg06742321 chr12:123595122 PITPNM2 -0.32 -6.06 -0.31 3.69e-9 Platelet count; LIHC cis rs1707322 0.686 rs3014239 chr1:46089801 G/A cg03146154 chr1:46216737 IPP -0.56 -9.5 -0.46 3.64e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs11098499 0.779 rs10857066 chr4:120286596 C/T cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.11 0.55 2.44e-28 Height; LIHC trans rs116095464 0.681 rs9687745 chr5:229309 C/T cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.82e-11 Breast cancer; LIHC cis rs6964587 0.626 rs7807765 chr7:91531974 C/A cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.29e-24 Breast cancer; LIHC cis rs918629 0.567 rs1423268 chr5:95256974 T/C cg10483112 chr5:95245456 ELL2 -0.38 -7.13 -0.36 5.83e-12 IgG glycosylation; LIHC cis rs881375 0.715 rs10760119 chr9:123646060 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.4 6.04 0.31 4.04e-9 Rheumatoid arthritis; LIHC cis rs12497850 0.931 rs3774628 chr3:48801840 C/T cg07636037 chr3:49044803 WDR6 0.89 15.95 0.65 3.36e-43 Parkinson's disease; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.65 0.62 4.57e-38 Prudent dietary pattern; LIHC cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg03264133 chr6:25882463 NA -0.54 -6.94 -0.35 1.92e-11 Intelligence (multi-trait analysis); LIHC cis rs17106184 1.000 rs17106219 chr1:50935031 C/T cg07174182 chr1:51127561 FAF1 -0.56 -6.55 -0.33 2.08e-10 Type 2 diabetes; LIHC cis rs804280 0.662 rs11250164 chr8:11610686 C/T cg25598624 chr8:12235727 FAM66A 0.3 6.11 0.31 2.77e-9 Myopia (pathological); LIHC cis rs7715806 0.500 rs72633982 chr5:75001321 C/T cg00601450 chr5:74908170 NA 0.58 7.1 0.36 7.09e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6570726 0.967 rs365515 chr6:145802833 C/T cg23711669 chr6:146136114 FBXO30 -0.5 -8.73 -0.43 1.13e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.754 rs1849457 chr4:120254355 A/G cg09307838 chr4:120376055 NA 0.7 10.87 0.51 7.44e-24 Corneal astigmatism; LIHC cis rs2257205 0.667 rs9904996 chr17:56711707 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs6089829 0.962 rs6062777 chr20:61663748 G/A cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs8177179 0.904 rs1130459 chr3:133465283 A/G cg16262614 chr3:133464971 TF 0.45 10.02 0.48 6.77e-21 Iron status biomarkers (transferrin levels); LIHC cis rs2153535 0.580 rs6938071 chr6:8464845 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs921968 0.643 rs2178019 chr2:219316303 G/A cg18887096 chr2:219472410 PLCD4 0.4 7.12 0.36 6.42e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs17345786 0.906 rs12638137 chr3:101150964 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.56 6.8 0.35 4.61e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs10876993 0.890 rs4760165 chr12:58063801 C/T cg15848620 chr12:58087721 OS9 -0.55 -7.45 -0.37 7.5e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs6840360 0.593 rs11723227 chr4:152689717 G/A cg22705602 chr4:152727874 NA -0.4 -8.47 -0.42 7.54e-16 Intelligence (multi-trait analysis); LIHC cis rs1843834 0.539 rs10177898 chr2:225437552 C/T cg12698349 chr2:225449008 CUL3 0.68 10.37 0.49 4.2e-22 IgE levels in asthmatics (D.p. specific); LIHC cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg08888203 chr3:10149979 C3orf24 0.44 5.79 0.3 1.57e-8 Alzheimer's disease; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg11062466 chr8:58055876 NA 0.49 7.98 0.4 2.21e-14 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg00343986 chr7:65444356 GUSB -0.41 -5.71 -0.3 2.45e-8 Aortic root size; LIHC cis rs4237845 0.551 rs116263297 chr12:58273445 A/C cg04478727 chr12:58166393 METTL1;FAM119B 0.58 8.04 0.4 1.52e-14 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.931 rs6791542 chr3:48787219 A/G cg07636037 chr3:49044803 WDR6 0.91 16.38 0.66 6.2e-45 Parkinson's disease; LIHC cis rs2404602 0.735 rs437131 chr15:76781051 C/T cg03037974 chr15:76606532 NA 0.66 11.78 0.54 4.1e-27 Blood metabolite levels; LIHC cis rs7020830 0.825 rs10973248 chr9:37197768 C/T cg14294708 chr9:37120828 ZCCHC7 1.16 27.36 0.83 3.84e-88 Schizophrenia; LIHC cis rs8180040 0.587 rs62246398 chr3:47066203 A/C cg27129171 chr3:47204927 SETD2 -0.54 -9.08 -0.44 8.92e-18 Colorectal cancer; LIHC cis rs6089584 0.606 rs2273989 chr20:60579138 G/A cg06108461 chr20:60628389 TAF4 -0.51 -6.81 -0.35 4.4e-11 Body mass index; LIHC cis rs7945705 0.818 rs2742552 chr11:8876852 C/T cg12365402 chr11:9010492 NRIP3 -0.25 -6.35 -0.32 7.05e-10 Hemoglobin concentration; LIHC cis rs2010672 0.500 rs4261511 chr15:91151276 C/G cg26821196 chr15:91095069 CRTC3 0.36 6.49 0.33 3.02e-10 Sum eosinophil basophil counts;Eosinophil percentage of white cells;Eosinophil counts; LIHC cis rs778371 0.697 rs2344611 chr2:233581937 A/G cg08000102 chr2:233561755 GIGYF2 0.77 9.45 0.46 5.39e-19 Schizophrenia; LIHC cis rs7582180 0.591 rs1030902 chr2:101007178 T/G cg14675211 chr2:100938903 LONRF2 0.54 8.41 0.41 1.09e-15 Intelligence (multi-trait analysis); LIHC cis rs7584330 0.868 rs13386290 chr2:238393136 G/C cg14458575 chr2:238380390 NA 0.42 6.55 0.33 2.16e-10 Prostate cancer; LIHC cis rs7712401 0.791 rs3822367 chr5:122146272 A/G cg18764291 chr5:122110994 SNX2 -0.36 -6.2 -0.32 1.66e-9 Mean platelet volume; LIHC cis rs3809566 0.710 rs4075583 chr15:63340227 C/T cg12160578 chr15:63334699 TPM1 -0.44 -6.36 -0.33 6.45e-10 Platelet count; LIHC cis rs7918232 0.882 rs10829190 chr10:27409555 C/T cg14240646 chr10:27532245 ACBD5 -0.66 -6.29 -0.32 9.9e-10 Breast cancer; LIHC cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg03264133 chr6:25882463 NA -0.63 -8.94 -0.44 2.56e-17 Blood metabolite levels; LIHC cis rs9467773 0.587 rs10946812 chr6:26344975 G/C cg09904177 chr6:26538194 HMGN4 -0.37 -5.83 -0.3 1.31e-8 Intelligence (multi-trait analysis); LIHC cis rs10426930 0.816 rs8101347 chr19:5044620 C/T cg18473234 chr19:5097819 KDM4B 0.54 6.79 0.34 4.86e-11 Monocyte percentage of white cells; LIHC cis rs7100689 0.622 rs10749569 chr10:82129892 G/A cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs7552404 0.924 rs7535991 chr1:76162624 C/T cg03433033 chr1:76189801 ACADM 0.69 10.58 0.5 8e-23 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4919087 0.715 rs13439 chr10:99006083 C/T cg25902810 chr10:99078978 FRAT1 -0.5 -5.72 -0.3 2.35e-8 Monocyte count; LIHC cis rs2153535 0.580 rs7775909 chr6:8477778 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.64 0.42 2.24e-16 Motion sickness; LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.87 0.8 1.07e-78 Prudent dietary pattern; LIHC cis rs8180040 0.966 rs12486969 chr3:47429003 G/C cg27129171 chr3:47204927 SETD2 -0.58 -9.8 -0.47 3.94e-20 Colorectal cancer; LIHC cis rs12286929 0.639 rs4938181 chr11:115041163 A/G cg04055981 chr11:115044050 NA 0.41 6.71 0.34 7.87e-11 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25220896 chr1:11004296 NA 0.42 6.98 0.35 1.53e-11 Cognitive function; LIHC cis rs9287719 0.674 rs10929690 chr2:10805974 T/C cg02829992 chr2:10710499 NA 0.39 6.01 0.31 4.68e-9 Prostate cancer; LIHC cis rs9916302 0.629 rs9972882 chr17:37807698 A/C cg00129232 chr17:37814104 STARD3 -0.54 -9.84 -0.47 2.7e-20 Glomerular filtration rate (creatinine); LIHC cis rs10744422 1.000 rs4759387 chr12:123377569 C/T cg07706471 chr12:123319906 HIP1R -0.56 -7.0 -0.35 1.39e-11 Schizophrenia; LIHC cis rs1975974 1.000 rs4889732 chr17:21721443 T/C cg18423549 chr17:21743878 NA -0.45 -5.97 -0.31 6.06e-9 Psoriasis; LIHC cis rs4730250 0.708 rs3801965 chr7:106825628 G/T cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Osteoarthritis; LIHC cis rs1144333 0.655 rs76532097 chr1:76320759 G/C cg22875332 chr1:76189707 ACADM 0.44 6.83 0.35 3.94e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs2777491 0.915 rs7165675 chr15:41614704 T/C cg18705301 chr15:41695430 NDUFAF1 -0.55 -8.15 -0.4 7.18e-15 Ulcerative colitis; LIHC cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg17971929 chr21:40555470 PSMG1 -0.49 -7.48 -0.37 6.39e-13 Cognitive function; LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg07677032 chr17:61819896 STRADA 0.43 6.32 0.32 8.12e-10 Prudent dietary pattern; LIHC cis rs2439831 0.867 rs2260160 chr15:43895643 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.38 0.33 5.92e-10 Lung cancer in ever smokers; LIHC cis rs34779708 0.766 rs7913451 chr10:35551525 T/C cg03585969 chr10:35415529 CREM 0.76 10.71 0.5 2.89e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.679 rs12679941 chr8:58051812 G/T cg02290350 chr8:58132656 NA 0.32 7.17 0.36 4.56e-12 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs12701220 0.817 rs59471534 chr7:1085224 G/A cg00990874 chr7:1149470 C7orf50 -0.63 -9.15 -0.44 5.26e-18 Bronchopulmonary dysplasia; LIHC trans rs3780486 0.846 rs7873903 chr9:33142728 G/A cg04842962 chr6:43655489 MRPS18A 1.07 25.0 0.8 3.33e-79 IgG glycosylation; LIHC trans rs2243480 1.000 rs1796228 chr7:66033084 G/A cg10756647 chr7:56101905 PSPH 1.02 12.11 0.55 2.53e-28 Diabetic kidney disease; LIHC cis rs67981189 0.613 rs221892 chr14:71611606 C/A cg15816911 chr14:71606274 NA -0.42 -6.73 -0.34 7.34e-11 Schizophrenia; LIHC cis rs12220238 1.000 rs7897778 chr10:75916105 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.83 0.35 3.82e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs801193 0.569 rs2659907 chr7:66164032 G/A cg11764359 chr7:65958608 NA 0.75 12.72 0.57 1.25e-30 Aortic root size; LIHC cis rs1784581 0.546 rs1954917 chr6:162447490 C/T cg17173639 chr6:162384350 PARK2 0.65 12.25 0.55 7.42e-29 Itch intensity from mosquito bite; LIHC cis rs7089973 0.604 rs10490909 chr10:116593532 C/T cg03647239 chr10:116582469 FAM160B1 0.42 6.34 0.32 7.37e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs416603 0.967 rs11644184 chr16:11365104 G/A cg00044050 chr16:11439710 C16orf75 -0.45 -5.95 -0.31 6.58e-9 Type 1 diabetes; LIHC cis rs922107 0.713 rs12129433 chr1:90059575 G/T cg15422784 chr1:90023713 LRRC8B -0.48 -7.74 -0.39 1.11e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs801193 0.569 rs2707824 chr7:66189243 A/G cg11764359 chr7:65958608 NA 0.76 12.98 0.57 1.28e-31 Aortic root size; LIHC cis rs477692 1.000 rs480643 chr10:131400308 A/G cg05714579 chr10:131428358 MGMT 0.48 7.96 0.4 2.53e-14 Response to temozolomide; LIHC cis rs875971 0.862 rs6944374 chr7:65686929 C/G cg18876405 chr7:65276391 NA -0.32 -5.87 -0.3 1.05e-8 Aortic root size; LIHC cis rs7587476 0.643 rs6714373 chr2:215719014 A/G cg04004882 chr2:215674386 BARD1 0.56 7.65 0.38 2.13e-13 Neuroblastoma; LIHC trans rs35110281 0.811 rs2838339 chr21:45075750 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO -0.44 -6.17 -0.32 1.98e-9 Mean corpuscular volume; LIHC trans rs983392 0.805 rs2123314 chr11:59966295 C/T cg17275991 chr19:58003312 ZNF419 -0.47 -6.15 -0.32 2.14e-9 Alzheimer's disease (late onset); LIHC cis rs8062405 0.964 rs72793809 chr16:28832382 C/T cg16576597 chr16:28551801 NUPR1 0.37 6.1 0.31 2.86e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs757081 0.606 rs679201 chr11:17200891 T/C cg15432903 chr11:17409602 KCNJ11 -0.42 -5.86 -0.3 1.07e-8 Systolic blood pressure; LIHC cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg06238570 chr21:40685208 BRWD1 -0.47 -7.66 -0.38 1.96e-13 Cognitive function; LIHC cis rs1538970 0.816 rs61788356 chr1:46006675 C/T cg05343316 chr1:45956843 TESK2 0.61 8.46 0.42 7.99e-16 Platelet count; LIHC cis rs832187 0.629 rs59971314 chr3:63914618 G/C cg16258503 chr3:63850278 ATXN7;THOC7 -0.52 -7.16 -0.36 5.1e-12 Schizophrenia; LIHC cis rs600806 0.713 rs12140694 chr1:109998386 C/T cg16275483 chr1:110013120 SYPL2 -0.47 -5.83 -0.3 1.27e-8 Intelligence (multi-trait analysis); LIHC cis rs6089829 0.962 rs1116450 chr20:61658210 T/C cg03213289 chr20:61660250 NA 0.51 9.06 0.44 1.04e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs2731664 0.792 rs335420 chr5:176898619 C/T cg23176889 chr5:176863531 GRK6 0.64 11.39 0.52 1.09e-25 Intelligence (multi-trait analysis); LIHC cis rs2645694 0.626 rs904050 chr4:77826089 T/G cg03477792 chr4:77819574 ANKRD56 0.6 8.56 0.42 3.76e-16 Emphysema distribution in smoking; LIHC cis rs1941023 0.503 rs7944025 chr11:60142538 C/A cg08716584 chr11:60157161 MS4A7 -0.35 -8.08 -0.4 1.1e-14 Congenital heart disease (maternal effect); LIHC cis rs10508774 0.759 rs12414205 chr10:32740040 A/G cg01819863 chr10:32635814 EPC1 0.61 5.81 0.3 1.45e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11997175 0.740 rs4467902 chr8:33693415 G/T cg04338863 chr8:33670619 NA 0.31 5.8 0.3 1.53e-8 Body mass index; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg06873352 chr17:61820015 STRADA 0.72 12.83 0.57 4.79e-31 Prudent dietary pattern; LIHC cis rs8141529 0.778 rs763073 chr22:29215542 G/A cg15103426 chr22:29168792 CCDC117 0.67 11.21 0.52 4.86e-25 Lymphocyte counts; LIHC cis rs1712517 0.904 rs7905968 chr10:105135319 C/T cg05636881 chr10:105038444 INA 0.45 6.94 0.35 2.01e-11 Migraine; LIHC cis rs67460515 0.892 rs10513564 chr3:161059762 A/G cg03342759 chr3:160939853 NMD3 -0.56 -8.17 -0.4 5.89e-15 Parkinson's disease; LIHC cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.85 11.02 0.51 2.25e-24 Alzheimer's disease; LIHC cis rs988712 0.705 rs11030104 chr11:27684517 C/T cg18117895 chr11:27722066 BDNF -0.54 -7.5 -0.38 5.57e-13 Obesity; LIHC cis rs6500602 0.627 rs841231 chr16:4583147 C/T cg08645402 chr16:4508243 NA -0.37 -6.52 -0.33 2.5e-10 Schizophrenia; LIHC cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg22105103 chr4:187893119 NA 0.29 7.18 0.36 4.26e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs860295 1.000 rs6427286 chr1:155723297 T/C cg02153340 chr1:155202674 NA -0.32 -5.91 -0.3 8.29e-9 Body mass index; LIHC cis rs875971 0.830 rs12673450 chr7:66009220 G/A cg11764359 chr7:65958608 NA 0.79 13.45 0.59 2.14e-33 Aortic root size; LIHC cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg10560079 chr2:191398806 TMEM194B 0.51 7.93 0.39 3.2e-14 Pulse pressure; LIHC cis rs2276314 1.000 rs2276314 chr18:33557466 C/T cg05985134 chr18:33552581 C18orf21 -0.49 -5.91 -0.3 8.33e-9 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs7520050 1.000 rs7540699 chr1:46338585 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg12310025 chr6:25882481 NA 0.84 11.29 0.52 2.53e-25 Blood metabolite levels; LIHC cis rs1215050 0.791 rs165247 chr4:98692399 A/G cg05340658 chr4:99064831 C4orf37 0.39 5.82 0.3 1.37e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs858239 0.932 rs1624451 chr7:23262435 A/T cg18081818 chr7:23246105 NA 0.42 6.27 0.32 1.1e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg03806693 chr22:41940476 POLR3H 1.13 13.08 0.58 5.61e-32 Vitiligo; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg11494091 chr17:61959527 GH2 0.45 8.32 0.41 2.12e-15 Prudent dietary pattern; LIHC cis rs5769765 0.908 rs4824109 chr22:50271460 T/C cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg25894440 chr7:65020034 NA -0.55 -6.31 -0.32 8.7e-10 Diabetic kidney disease; LIHC cis rs634534 0.532 rs12794370 chr11:65770413 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.24 0.45 2.62e-18 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs9359856 0.564 rs34732313 chr6:90368380 G/A cg13799429 chr6:90582589 CASP8AP2 -0.66 -6.27 -0.32 1.11e-9 Bipolar disorder; LIHC cis rs2074585 0.713 rs2589941 chr15:90931457 C/T cg22089800 chr15:90895588 ZNF774 0.57 7.83 0.39 6.29e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs151349 1.000 rs108727 chr20:57584890 C/T cg23907860 chr20:57583709 CTSZ 0.42 7.01 0.35 1.25e-11 Platelet distribution width; LIHC cis rs7647973 0.626 rs9829155 chr3:49817450 T/C cg03060546 chr3:49711283 APEH -0.59 -6.86 -0.35 3.28e-11 Menarche (age at onset); LIHC cis rs11583043 1.000 rs7535068 chr1:101490329 T/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.86 0.43 4.4e-17 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs1814175 0.650 rs6486000 chr11:49659090 T/A cg18944383 chr4:111397179 ENPEP 0.25 6.12 0.31 2.5e-9 Height; LIHC cis rs477895 1.000 rs7938380 chr11:64034866 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 7.92 0.39 3.26e-14 Mean platelet volume; LIHC cis rs61712019 0.837 rs12329048 chr2:77706281 C/G cg11252801 chr2:77748917 LRRTM4 0.54 7.41 0.37 1.03e-12 Schizophrenia; LIHC cis rs1707322 1.000 rs4660906 chr1:46470860 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.4 0.33 5.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs13325613 0.915 rs35613615 chr3:46265243 T/C cg26337592 chr1:153642686 ILF2 0.68 6.2 0.32 1.66e-9 Monocyte count; LIHC cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg08888203 chr3:10149979 C3orf24 0.56 6.37 0.33 6.04e-10 Alzheimer's disease; LIHC cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.06 0.31 3.6e-9 Menopause (age at onset); LIHC cis rs244293 0.831 rs12453699 chr17:53171846 C/A cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.45 0.37 7.54e-13 Menarche (age at onset); LIHC trans rs60752752 0.852 rs73018470 chr1:153369532 G/A cg14901121 chr8:98817630 LAPTM4B -0.43 -7.17 -0.36 4.6e-12 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs13191362 0.935 rs34141091 chr6:162953893 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.7 6.05 0.31 3.91e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1552244 0.554 rs13081079 chr3:10056348 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.62e-13 Alzheimer's disease; LIHC cis rs10791097 0.694 rs4937583 chr11:130741606 A/G cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10791097 0.694 rs4937583 chr11:130741606 A/G cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2404602 0.716 rs7164813 chr15:76708066 T/C cg03037974 chr15:76606532 NA 0.8 16.47 0.67 2.75e-45 Blood metabolite levels; LIHC cis rs611744 0.967 rs677842 chr8:109212468 A/G cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs35306767 0.953 rs34405399 chr10:981015 G/A cg26597838 chr10:835615 NA 0.95 11.15 0.52 7.63e-25 Eosinophil percentage of granulocytes; LIHC cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg13397359 chr6:42928475 GNMT 0.86 12.89 0.57 2.82e-31 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs727505 0.908 rs56155943 chr7:124606346 T/G cg23710748 chr7:124431027 NA -0.33 -5.97 -0.31 5.93e-9 Lewy body disease; LIHC cis rs637571 0.546 rs11227309 chr11:65584512 A/C cg26695010 chr11:65641043 EFEMP2 0.44 6.17 0.32 1.91e-9 Eosinophil percentage of white cells; LIHC cis rs116095464 0.558 rs7708182 chr5:234788 C/G cg22496380 chr5:211416 CCDC127 -1.03 -10.71 -0.5 2.89e-23 Breast cancer; LIHC cis rs2204008 0.665 rs11179830 chr12:38220966 T/C cg13010199 chr12:38710504 ALG10B 0.48 5.79 0.3 1.58e-8 Bladder cancer; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg06873352 chr17:61820015 STRADA 0.72 12.75 0.57 1.04e-30 Prudent dietary pattern; LIHC trans rs12752401 0.717 rs34542611 chr1:103028047 C/T cg03332897 chr19:740442 PALM 0.46 6.04 0.31 3.94e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC cis rs1371867 0.846 rs1788180 chr8:101333368 A/G cg06636551 chr8:101224915 SPAG1 -0.47 -8.72 -0.43 1.26e-16 Atrioventricular conduction; LIHC cis rs6586163 0.934 rs7897395 chr10:90754607 T/C cg03111039 chr10:90751583 FAS;ACTA2 -0.57 -8.36 -0.41 1.64e-15 Chronic lymphocytic leukemia; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg21448741 chr8:58168803 NA 0.35 6.52 0.33 2.58e-10 Developmental language disorder (linguistic errors); LIHC cis rs1707322 1.000 rs785497 chr1:46591903 G/C cg03146154 chr1:46216737 IPP -0.46 -7.28 -0.37 2.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9790314 0.638 rs1374793 chr3:160638505 G/A cg03342759 chr3:160939853 NMD3 0.57 7.49 0.38 5.91e-13 Morning vs. evening chronotype; LIHC cis rs992157 0.687 rs35271699 chr2:219117482 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.42 0.59 2.73e-33 Colorectal cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg24264674 chr11:8285509 LMO1 0.4 6.25 0.32 1.25e-9 Calcium levels; LIHC cis rs2204008 0.528 rs11503820 chr12:38395379 G/A cg26384229 chr12:38710491 ALG10B -0.47 -5.97 -0.31 5.79e-9 Bladder cancer; LIHC cis rs7572733 0.515 rs1836234 chr2:198882873 T/G cg00792783 chr2:198669748 PLCL1 0.41 5.93 0.31 7.58e-9 Dermatomyositis; LIHC cis rs6694270 0.529 rs12565650 chr1:19108355 G/A cg26220594 chr1:19110978 NA -0.36 -6.15 -0.32 2.18e-9 Drug-induced liver injury (nitrofurantoin); LIHC cis rs1707322 0.963 rs11211229 chr1:46400517 A/C cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.77e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9649213 0.537 rs35997266 chr7:97965566 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.35e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs7582720 0.943 rs72928610 chr2:203838961 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg11502198 chr6:26597334 ABT1 0.64 10.02 0.48 6.75e-21 Intelligence (multi-trait analysis); LIHC cis rs4718428 0.705 rs11028 chr7:66276217 T/C cg18252515 chr7:66147081 NA -0.69 -9.49 -0.46 3.98e-19 Corneal structure; LIHC cis rs6432852 0.516 rs2304002 chr2:166714095 G/A cg15343463 chr2:166634454 GALNT3 0.38 6.09 0.31 2.98e-9 Diabetic kidney disease; LIHC cis rs7131987 0.650 rs10843384 chr12:29472409 C/T cg14222432 chr12:29376421 FAR2 0.36 6.96 0.35 1.7e-11 QT interval; LIHC cis rs8180040 0.701 rs34103310 chr3:47073266 C/T cg16586182 chr3:47516702 SCAP -0.5 -9.11 -0.44 7.02e-18 Colorectal cancer; LIHC trans rs72960926 0.744 rs3898077 chr6:74959122 G/A cg07247405 chr1:2484626 LOC115110 0.54 6.46 0.33 3.61e-10 Metabolite levels (MHPG); LIHC cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg12064134 chr16:90016061 DEF8 -0.43 -5.82 -0.3 1.34e-8 Skin colour saturation; LIHC cis rs1564271 0.704 rs1780191 chr10:26994412 T/C cg13837822 chr10:26931731 LOC731789 0.35 6.27 0.32 1.09e-9 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs2075371 0.865 rs2544172 chr7:133931338 T/C cg20476274 chr7:133979776 SLC35B4 0.72 11.99 0.54 6.73e-28 Mean platelet volume; LIHC cis rs425535 0.619 rs10033521 chr4:74829332 C/A cg02530824 chr4:74847766 PF4 -0.37 -5.95 -0.31 6.57e-9 Blood protein levels; LIHC cis rs9916302 0.851 rs11078906 chr17:37662767 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.34 -0.59 5.58e-33 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.691 rs10028773 chr4:120265259 C/G cg09307838 chr4:120376055 NA -0.65 -10.18 -0.48 1.88e-21 Corneal astigmatism; LIHC cis rs10916814 0.632 rs10916817 chr1:20897294 C/T cg24502330 chr1:20914028 CDA -0.31 -6.76 -0.34 6.01e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1707322 0.686 rs2991986 chr1:46081282 A/G cg03146154 chr1:46216737 IPP -0.57 -9.63 -0.46 1.37e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs116095464 0.558 rs1968374 chr5:249025 A/C cg22857025 chr5:266934 NA -1.41 -14.94 -0.63 3.26e-39 Breast cancer; LIHC cis rs826838 0.904 rs11612004 chr12:39204282 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.96 0.31 6.39e-9 Heart rate; LIHC cis rs9902453 0.765 rs34585141 chr17:28336432 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC cis rs5753037 0.585 rs249396 chr22:30213972 T/G cg01021169 chr22:30184971 ASCC2 -0.44 -8.7 -0.43 1.39e-16 Type 1 diabetes; LIHC cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg10295955 chr4:187884368 NA -0.96 -21.95 -0.76 2.89e-67 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.932 rs12490058 chr3:47529063 T/C cg16586182 chr3:47516702 SCAP -0.58 -11.26 -0.52 3.21e-25 Colorectal cancer; LIHC trans rs72829446 0.530 rs66616380 chr17:7380188 C/A cg08566640 chr11:64091735 NA -0.69 -6.54 -0.33 2.2e-10 Androgen levels; LIHC cis rs17428076 0.874 rs17581347 chr2:172682601 T/C cg13550731 chr2:172543902 DYNC1I2 0.38 6.21 0.32 1.55e-9 Myopia; LIHC cis rs1034435 1.000 rs6007867 chr22:48889170 T/G cg05992904 chr22:48892994 FAM19A5 -0.46 -9.09 -0.44 8.32e-18 Late-onset Alzheimer's disease; LIHC cis rs10779751 1.000 rs4845858 chr1:11304720 C/T cg08854313 chr1:11322531 MTOR 0.87 16.31 0.66 1.24e-44 Body mass index; LIHC cis rs11719291 0.584 rs13080725 chr3:49076092 G/A cg00383909 chr3:49044727 WDR6 0.85 7.04 0.36 1.09e-11 Cognitive function; LIHC cis rs2580764 0.566 rs2968795 chr2:55287989 G/A cg09592903 chr2:55203963 RTN4 0.62 11.38 0.52 1.14e-25 Mean platelet volume; LIHC cis rs2153535 0.580 rs7341381 chr6:8470537 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.42 0.41 1.06e-15 Motion sickness; LIHC cis rs2019960 0.759 rs2720697 chr8:129173118 C/G cg15331705 chr8:129180010 NA -0.36 -6.63 -0.34 1.34e-10 Hodgkin's lymphoma;Multiple sclerosis; LIHC cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg00149659 chr3:10157352 C3orf10 0.69 7.06 0.36 9.46e-12 Alzheimer's disease; LIHC cis rs9814567 0.964 rs12492930 chr3:134222722 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.95 -0.31 6.7e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg19302996 chr17:73780495 UNK -0.51 -6.11 -0.31 2.64e-9 Psoriasis; LIHC cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg02931644 chr1:25747376 RHCE 0.35 7.7 0.38 1.46e-13 Erythrocyte sedimentation rate; LIHC cis rs12744310 0.887 rs12724690 chr1:41800257 T/C cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs798554 0.836 rs798500 chr7:2790685 C/T cg13628971 chr7:2884303 GNA12 -0.53 -7.83 -0.39 6.13e-14 Height; LIHC cis rs798554 0.607 rs1182151 chr7:2909225 C/G cg04166393 chr7:2884313 GNA12 0.45 6.03 0.31 4.29e-9 Height; LIHC cis rs1707322 0.648 rs4439382 chr1:46150805 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.38 0.37 1.22e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12220238 0.908 rs10824077 chr10:75887038 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.65 -6.81 -0.35 4.28e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1046896 0.553 rs56775875 chr17:80831291 G/T cg02711726 chr17:80685570 FN3KRP -0.44 -8.16 -0.4 6.4e-15 Glycated hemoglobin levels; LIHC cis rs17401966 0.838 rs912963 chr1:10348042 C/T cg19773385 chr1:10388646 KIF1B -0.4 -7.35 -0.37 1.45e-12 Hepatocellular carcinoma; LIHC cis rs992157 1.000 rs10932766 chr2:219122090 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.81 0.57 5.84e-31 Colorectal cancer; LIHC cis rs61677309 0.638 rs4245180 chr11:118144512 G/A cg06090739 chr11:118230722 UBE4A 0.32 6.03 0.31 4.34e-9 Lung cancer in ever smokers; LIHC cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs4970966 1.000 rs4970966 chr1:150584103 A/C cg18016565 chr1:150552671 MCL1 0.39 6.11 0.31 2.78e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs9916302 0.851 rs7220650 chr17:37487168 A/G cg03013999 chr17:37608204 MED1 -0.35 -5.98 -0.31 5.66e-9 Glomerular filtration rate (creatinine); LIHC cis rs6570726 0.935 rs454370 chr6:145846729 T/G cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.866 rs10184 chr14:90744672 G/A cg14092571 chr14:90743983 NA 0.44 6.83 0.35 3.91e-11 Mortality in heart failure; LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg00656387 chr3:40428638 ENTPD3 0.49 8.34 0.41 1.84e-15 Renal cell carcinoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11814422 chr18:47018265 SNORD58A;RPL17;SNORD58B 0.4 6.39 0.33 5.4e-10 Cognitive function; LIHC cis rs11711311 1.000 rs9811200 chr3:113531180 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -6.79 -0.34 5.05e-11 IgG glycosylation; LIHC cis rs7615952 0.736 rs13063122 chr3:125643860 G/A cg05084668 chr3:125655381 ALG1L -0.55 -7.73 -0.39 1.19e-13 Blood pressure (smoking interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12594348 chr12:51477468 CSRNP2 0.47 6.34 0.32 7.42e-10 Lung function (FEV1/FVC); LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.78 0.62 1.38e-38 Prudent dietary pattern; LIHC cis rs17685 0.775 rs11761172 chr7:75761547 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg19626725 chr5:178986131 RUFY1 0.39 6.06 0.31 3.53e-9 Lung cancer; LIHC cis rs9581857 0.685 rs9319367 chr13:28042197 T/C cg22138327 chr13:27999177 GTF3A 0.76 6.24 0.32 1.26e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.03 9.99 0.48 8.36e-21 Platelet count; LIHC cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.58 0.34 1.78e-10 Bipolar disorder; LIHC cis rs3761218 1.000 rs3761219 chr20:3776368 T/C cg25011176 chr20:3776985 CDC25B -0.48 -6.67 -0.34 1.01e-10 Bipolar disorder; LIHC trans rs7613875 0.537 rs6446195 chr3:50070853 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.55 -0.33 2.1e-10 Body mass index; LIHC cis rs910316 0.737 rs175055 chr14:75488946 T/G cg08847533 chr14:75593920 NEK9 -0.87 -17.73 -0.69 2.38e-50 Height; LIHC cis rs2760061 0.624 rs10442629 chr1:228191070 T/A cg01200585 chr1:228362443 C1orf69 0.49 6.29 0.32 9.72e-10 Diastolic blood pressure; LIHC cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg19318889 chr4:1322082 MAEA 0.47 7.91 0.39 3.69e-14 Obesity-related traits; LIHC cis rs9649213 0.593 rs6968144 chr7:97915697 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.98 -0.31 5.65e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs252716 1 rs252716 chr5:110425063 G/C cg04022379 chr5:110408740 TSLP -0.48 -7.64 -0.38 2.19e-13 Eosinophilic esophagitis; LIHC cis rs1348850 0.874 rs952746 chr2:178306584 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.24 0.58 1.38e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs763121 0.853 rs1062687 chr22:39134715 T/C cg14440974 chr22:39074834 NA -0.39 -6.49 -0.33 2.96e-10 Menopause (age at onset); LIHC cis rs1113500 0.933 rs4517375 chr1:108638330 A/C cg06207961 chr1:108661230 NA -0.38 -7.46 -0.37 7.27e-13 Growth-regulated protein alpha levels; LIHC cis rs2251381 0.808 rs7364112 chr21:30548968 C/A cg24692254 chr21:30365293 RNF160 0.68 9.48 0.46 4.27e-19 Selective IgA deficiency; LIHC cis rs7089973 0.604 rs7895830 chr10:116625776 A/G cg03647239 chr10:116582469 FAM160B1 0.46 6.75 0.34 6.33e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9381040 0.610 rs6940356 chr6:41020360 C/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.2 -0.32 1.66e-9 Alzheimer's disease (late onset); LIHC cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg19318889 chr4:1322082 MAEA -0.47 -7.79 -0.39 8.06e-14 Obesity-related traits; LIHC cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9473924 0.580 rs60100577 chr6:50816134 C/T cg14470998 chr6:50812995 TFAP2B 0.93 10.62 0.5 6.08e-23 Body mass index; LIHC cis rs6426558 0.537 rs2492630 chr1:227286931 A/G cg10327440 chr1:227177885 CDC42BPA 0.44 6.72 0.34 7.73e-11 Neutrophil percentage of white cells; LIHC cis rs11122272 0.735 rs2790882 chr1:231532783 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.67 10.47 0.49 1.93e-22 Hemoglobin concentration; LIHC cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg04352962 chr1:209979756 IRF6 0.38 5.78 0.3 1.71e-8 Cleft lip with or without cleft palate; LIHC cis rs17685 0.753 rs11764129 chr7:75761890 T/C cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs243505 0.762 rs3779036 chr7:148488507 C/T cg09806900 chr7:148480153 CUL1 0.45 6.7 0.34 8.77e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2933343 1.000 rs1680784 chr3:128644458 A/G cg25356066 chr3:128598488 ACAD9 0.53 7.09 0.36 7.83e-12 IgG glycosylation; LIHC cis rs911119 0.955 rs1555355 chr20:23594580 T/C cg16589663 chr20:23618590 CST3 0.72 7.54 0.38 4.32e-13 Chronic kidney disease; LIHC cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg03264133 chr6:25882463 NA -0.64 -9.15 -0.44 5.31e-18 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07145255 chr5:59995354 DEPDC1B 0.47 6.95 0.35 1.82e-11 Pancreatic cancer; LIHC cis rs829880 0.789 rs1096146 chr12:98850966 A/G cg25150519 chr12:98850993 NA 0.63 9.58 0.46 2.14e-19 Colonoscopy-negative controls vs population controls; LIHC cis rs2842992 0.830 rs1475123 chr6:160178007 A/G cg11366901 chr6:160182831 ACAT2 0.85 12.84 0.57 4.67e-31 Age-related macular degeneration (geographic atrophy); LIHC cis rs7772486 0.875 rs2814869 chr6:146315509 G/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.2 -0.32 1.6e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1008375 0.966 rs4698621 chr4:17587565 C/T cg02297831 chr4:17616191 MED28 0.47 7.17 0.36 4.66e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg03354898 chr7:1950403 MAD1L1 -0.37 -5.74 -0.3 2.07e-8 Bipolar disorder and schizophrenia; LIHC cis rs10857712 0.754 rs7921041 chr10:135229239 G/C cg19623624 chr10:135278901 LOC619207 -0.45 -7.11 -0.36 6.77e-12 Systemic lupus erythematosus; LIHC trans rs867371 1.000 rs7166570 chr15:82466221 C/T cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.11 -0.36 6.84e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs9611565 0.592 rs1811113 chr22:42073134 C/T cg06634786 chr22:41940651 POLR3H 0.71 7.31 0.37 1.95e-12 Vitiligo; LIHC cis rs2425143 1.000 rs113203744 chr20:34253656 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.89 -0.3 9.45e-9 Blood protein levels; LIHC cis rs12135062 0.851 rs2651927 chr1:3101762 A/C cg21609526 chr1:3105151 PRDM16 -0.29 -6.62 -0.34 1.42e-10 Migraine; LIHC cis rs7959452 0.605 rs12819406 chr12:69696400 G/T cg20891283 chr12:69753455 YEATS4 0.81 15.47 0.64 2.8e-41 Blood protein levels; LIHC cis rs9467773 1.000 rs6925895 chr6:26572165 G/T cg09904177 chr6:26538194 HMGN4 0.66 13.67 0.59 3.1e-34 Intelligence (multi-trait analysis); LIHC trans rs526821 0.595 rs499446 chr11:55355722 A/G cg15704280 chr7:45808275 SEPT13 -0.52 -7.83 -0.39 6.39e-14 Pediatric bone mineral density (spine); LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg21850448 chr4:88023169 AFF1 0.28 6.04 0.31 3.94e-9 Oropharynx cancer; LIHC cis rs8067354 0.872 rs1295925 chr17:57910263 T/C cg13753209 chr17:57696993 CLTC -0.59 -8.85 -0.43 4.64e-17 Hemoglobin concentration; LIHC cis rs17125944 0.615 rs1998777 chr14:53295706 C/T cg00686598 chr14:53173677 PSMC6 -0.82 -9.66 -0.46 1.15e-19 Alzheimer's disease (late onset); LIHC trans rs3783890 1.000 rs1503960 chr14:93778741 T/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.26 0.32 1.14e-9 Body mass index; LIHC cis rs67478160 0.643 rs11626377 chr14:104234357 G/A cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.75 -0.39 1.09e-13 Schizophrenia; LIHC cis rs12477438 0.520 rs11685759 chr2:99766217 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs10078 0.848 rs890985 chr5:479746 C/G cg24955955 chr5:415729 AHRR 0.48 9.33 0.45 1.41e-18 Fat distribution (HIV); LIHC trans rs10411161 0.810 rs17778711 chr19:52385300 A/G cg22319618 chr22:45562946 NUP50 -0.61 -7.41 -0.37 9.93e-13 Breast cancer; LIHC cis rs5769707 0.935 rs5770594 chr22:50018497 G/A cg01652190 chr22:50026171 C22orf34 -0.31 -7.15 -0.36 5.15e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs12477438 0.520 rs13018891 chr2:99755099 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.37 0.77 6.21e-69 Chronic sinus infection; LIHC cis rs2115630 0.967 rs10438428 chr15:85330745 C/T cg11189052 chr15:85197271 WDR73 -0.38 -5.78 -0.3 1.71e-8 P wave terminal force; LIHC cis rs1976403 0.633 rs1697422 chr1:21821897 T/C cg20417195 chr1:21767127 NBPF3 0.39 6.03 0.31 4.22e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs3806843 0.864 rs2531343 chr5:140129346 A/G cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7700895 0.729 rs3777182 chr5:95263752 T/A cg10483112 chr5:95245456 ELL2 -0.38 -6.63 -0.34 1.33e-10 IgG glycosylation; LIHC cis rs921968 0.613 rs1427445 chr2:219555573 C/A cg02985541 chr2:219472218 PLCD4 -0.38 -6.43 -0.33 4.32e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.11 0.31 2.7e-9 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg10372485 chr13:111294754 CARS2 -0.41 -6.31 -0.32 8.8e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs939574 0.722 rs55951006 chr2:220132151 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.93 6.28 0.32 1e-9 Platelet distribution width; LIHC cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg16405210 chr4:1374714 KIAA1530 -0.42 -6.33 -0.32 7.5e-10 Obesity-related traits; LIHC cis rs780096 0.526 rs4803 chr2:27667297 A/G cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.15 -0.32 2.22e-9 Total body bone mineral density; LIHC cis rs9303280 0.806 rs9909593 chr17:37970149 C/T cg11212589 chr17:38028394 ZPBP2 -0.31 -6.13 -0.31 2.44e-9 Self-reported allergy; LIHC cis rs10911232 0.507 rs4442336 chr1:182982538 T/G ch.1.3577855R chr1:183094577 LAMC1 0.58 10.0 0.48 7.88e-21 Hypertriglyceridemia; LIHC cis rs7945705 0.902 rs2568059 chr11:8884161 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -9.35 -0.45 1.22e-18 Hemoglobin concentration; LIHC cis rs6088580 0.524 rs6088575 chr20:33273403 C/T cg07148914 chr20:33460835 GGT7 0.45 6.18 0.32 1.87e-9 Glomerular filtration rate (creatinine); LIHC cis rs17826219 0.561 rs4085382 chr17:29071202 T/C cg14067834 chr17:29058358 SUZ12P 0.69 7.14 0.36 5.51e-12 Body mass index; LIHC cis rs12477438 0.520 rs6708576 chr2:99801308 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.2 21.1 0.75 6.92e-64 Chronic sinus infection; LIHC trans rs1005277 0.579 rs2103938 chr10:38493998 T/G cg27523141 chr10:43048294 ZNF37B 0.39 6.55 0.33 2.11e-10 Extrinsic epigenetic age acceleration; LIHC trans rs877282 0.898 rs11253348 chr10:765852 C/T cg22713356 chr15:30763199 NA 1.41 12.37 0.56 2.77e-29 Uric acid levels; LIHC cis rs60871478 0.786 rs62432898 chr7:826102 G/A cg00934597 chr7:893267 UNC84A 0.48 5.79 0.3 1.57e-8 Cerebrospinal P-tau181p levels; LIHC cis rs9393692 0.645 rs4145910 chr6:26313305 T/C cg00631329 chr6:26305371 NA -0.5 -7.89 -0.39 4.18e-14 Educational attainment; LIHC cis rs1670533 1.000 rs62294756 chr4:1097676 G/A cg27284194 chr4:1044797 NA -0.61 -8.99 -0.44 1.73e-17 Recombination rate (females); LIHC cis rs4237845 0.537 rs10747787 chr12:58260657 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.57 8.12 0.4 8.68e-15 Intelligence (multi-trait analysis); LIHC trans rs7618501 0.699 rs6446187 chr3:49907111 C/A cg21659725 chr3:3221576 CRBN 0.73 11.46 0.53 5.94e-26 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg06656553 chr16:89960601 TCF25 -0.44 -5.94 -0.31 6.94e-9 Skin colour saturation; LIHC cis rs4788570 0.667 rs9929840 chr16:71800942 C/T cg06353428 chr16:71660113 MARVELD3 -1.28 -12.62 -0.56 2.95e-30 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg03517284 chr6:25882590 NA -0.94 -12.25 -0.55 7.33e-29 Intelligence (multi-trait analysis); LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg17178900 chr1:205818956 PM20D1 0.66 9.92 0.47 1.53e-20 Menarche (age at onset); LIHC cis rs2607426 0.681 rs10420685 chr19:41235120 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.52 -6.2 -0.32 1.67e-9 Blood protein levels; LIHC cis rs829880 0.570 rs844205 chr12:98846053 A/G cg25150519 chr12:98850993 NA 0.57 8.36 0.41 1.6e-15 Colonoscopy-negative controls vs population controls; LIHC cis rs2991971 0.967 rs2275276 chr1:45973928 C/T cg15605315 chr1:45957053 TESK2 0.49 7.04 0.36 1.07e-11 High light scatter reticulocyte count; LIHC cis rs1506636 1.000 rs7357252 chr7:123369856 C/T cg03229431 chr7:123269106 ASB15 -0.62 -12.58 -0.56 4.45e-30 Plateletcrit;Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02056921 chr1:901892 PLEKHN1 0.41 6.21 0.32 1.56e-9 Pancreatic cancer; LIHC cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg08888203 chr3:10149979 C3orf24 0.61 7.19 0.36 4.19e-12 Alzheimer's disease; LIHC cis rs2153535 0.580 rs9505446 chr6:8448691 T/C cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC cis rs10792665 0.724 rs7940718 chr11:82696885 C/G cg24227371 chr11:82718527 RAB30 -0.38 -9.44 -0.45 5.95e-19 Obesity-related traits; LIHC cis rs10861342 1.000 rs7136344 chr12:105528268 A/G cg23923672 chr12:105501055 KIAA1033 0.68 8.46 0.42 7.85e-16 IgG glycosylation; LIHC cis rs826838 1.000 rs826888 chr12:39104719 C/G cg26384229 chr12:38710491 ALG10B -0.58 -8.62 -0.42 2.57e-16 Heart rate; LIHC cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg17691542 chr6:26056736 HIST1H1C -0.38 -5.81 -0.3 1.43e-8 Height; LIHC cis rs10779751 1.000 rs7544489 chr1:11299511 A/G cg08854313 chr1:11322531 MTOR -0.85 -15.0 -0.63 1.94e-39 Body mass index; LIHC cis rs6840360 0.934 rs6817058 chr4:152603865 T/C cg22705602 chr4:152727874 NA -0.29 -6.05 -0.31 3.78e-9 Intelligence (multi-trait analysis); LIHC cis rs9733 0.621 rs6669122 chr1:150591732 A/G cg18016565 chr1:150552671 MCL1 -0.54 -11.02 -0.51 2.3e-24 Tonsillectomy; LIHC cis rs2153535 0.580 rs7755284 chr6:8457479 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs12477438 0.520 rs34252185 chr2:99737646 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg11965913 chr1:205819406 PM20D1 0.76 11.04 0.51 1.85e-24 Menarche (age at onset); LIHC cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg00684032 chr4:1343700 KIAA1530 0.5 7.3 0.37 2.01e-12 Obesity-related traits; LIHC cis rs7100689 0.646 rs1953971 chr10:82145647 G/C cg01528321 chr10:82214614 TSPAN14 0.85 12.01 0.54 5.59e-28 Post bronchodilator FEV1; LIHC cis rs7772486 0.875 rs2777484 chr6:146334162 A/G cg13319975 chr6:146136371 FBXO30 -0.34 -5.78 -0.3 1.72e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs1410766 chr6:8525360 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.57 0.53 2.35e-26 Motion sickness; LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg06497051 chr1:156261200 TMEM79 0.38 6.05 0.31 3.83e-9 Tonsillectomy; LIHC cis rs9916302 0.718 rs7219909 chr17:37706243 C/T cg00129232 chr17:37814104 STARD3 -0.41 -6.6 -0.34 1.58e-10 Glomerular filtration rate (creatinine); LIHC cis rs6665290 0.669 rs3768423 chr1:227177293 G/A cg10327440 chr1:227177885 CDC42BPA -1.12 -24.08 -0.79 1.29e-75 Myeloid white cell count; LIHC cis rs9457247 0.765 rs9457256 chr6:167436461 T/C cg12798992 chr6:167411361 FGFR1OP 0.48 7.32 0.37 1.77e-12 Crohn's disease; LIHC cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg08888203 chr3:10149979 C3orf24 -0.53 -6.45 -0.33 3.93e-10 Alzheimer's disease; LIHC cis rs6691722 0.503 rs6667695 chr1:24707669 G/A cg18323236 chr1:24743029 NIPAL3 0.41 7.41 0.37 9.79e-13 Response to interferon beta in multiple sclerosis; LIHC cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg13047869 chr3:10149882 C3orf24 0.41 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg02034447 chr16:89574710 SPG7 0.49 7.37 0.37 1.29e-12 Multiple myeloma (IgH translocation); LIHC cis rs3736485 0.966 rs12372948 chr15:51894311 A/G cg08986416 chr15:51914746 DMXL2 -0.41 -6.09 -0.31 2.95e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7927771 0.524 rs3816605 chr11:47857253 T/C cg20307385 chr11:47447363 PSMC3 0.71 10.55 0.5 1.01e-22 Subjective well-being; LIHC cis rs2075371 0.933 rs1421482 chr7:133964383 A/G cg20476274 chr7:133979776 SLC35B4 0.73 12.68 0.57 1.81e-30 Mean platelet volume; LIHC cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg27170947 chr2:26402098 FAM59B 0.66 8.23 0.41 3.92e-15 Gut microbiome composition (summer); LIHC cis rs7647973 1.000 rs10155014 chr3:49432321 C/T cg07636037 chr3:49044803 WDR6 0.5 6.23 0.32 1.38e-9 Menarche (age at onset); LIHC cis rs3106136 0.678 rs1529339 chr4:95297283 T/A cg11021082 chr4:95130006 SMARCAD1 0.36 6.14 0.32 2.27e-9 Capecitabine sensitivity; LIHC cis rs507080 0.771 rs523715 chr11:118574188 G/A cg04173919 chr11:118528438 PHLDB1 0.32 6.02 0.31 4.44e-9 Serum metabolite levels; LIHC cis rs72781680 0.706 rs72796108 chr2:23904990 C/A cg08917208 chr2:24149416 ATAD2B 0.98 8.06 0.4 1.29e-14 Lymphocyte counts; LIHC cis rs1008375 0.932 rs4698628 chr4:17608620 A/G cg02297831 chr4:17616191 MED28 0.45 6.96 0.35 1.76e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs950027 0.967 rs2643718 chr15:45794662 T/C cg26924012 chr15:45694286 SPATA5L1 0.45 6.78 0.34 5.22e-11 Response to fenofibrate (adiponectin levels); LIHC cis rs1816752 0.905 rs9511262 chr13:25012023 C/T cg22771759 chr13:24902376 NA 0.32 6.8 0.35 4.62e-11 Obesity-related traits; LIHC cis rs7582180 0.629 rs13031906 chr2:100939524 T/C cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg09455208 chr3:40491958 NA -0.36 -7.29 -0.37 2.18e-12 Renal cell carcinoma; LIHC cis rs7224737 0.956 rs8081900 chr17:40289875 G/A cg20291162 chr17:40259547 DHX58 -0.4 -6.36 -0.33 6.38e-10 Fibrinogen levels; LIHC cis rs739401 0.595 rs6578305 chr11:3001120 C/T cg20651018 chr11:3035856 CARS -0.35 -5.99 -0.31 5.34e-9 Longevity; LIHC trans rs9747201 1.000 rs58472289 chr17:80111895 G/T cg07393940 chr7:158741817 NA -0.58 -6.83 -0.35 3.81e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9790314 0.586 rs16832279 chr3:161120483 C/T cg17135325 chr3:160939158 NMD3 0.47 7.11 0.36 6.79e-12 Morning vs. evening chronotype; LIHC cis rs8180040 0.701 rs11130111 chr3:47009805 C/T cg27129171 chr3:47204927 SETD2 0.62 10.8 0.5 1.4e-23 Colorectal cancer; LIHC trans rs1814175 0.645 rs28441045 chr11:50048971 C/T cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs6762477 0.748 rs34877766 chr3:50234126 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.54 8.27 0.41 3.02e-15 Menarche (age at onset); LIHC trans rs11098499 0.604 rs2389886 chr4:120570422 C/T cg25214090 chr10:38739885 LOC399744 0.55 8.89 0.43 3.58e-17 Corneal astigmatism; LIHC cis rs4920343 0.710 rs638256 chr1:19091182 C/A cg19637330 chr1:19110922 NA 0.35 6.42 0.33 4.45e-10 Knee osteoarthritis; LIHC cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg22963979 chr7:1858916 MAD1L1 -0.42 -6.67 -0.34 1e-10 Bipolar disorder and schizophrenia; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09587826 chr20:62204140 PRIC285 0.47 6.73 0.34 7.14e-11 Hepatitis; LIHC cis rs7551222 0.614 rs4951385 chr1:204454165 C/T cg20240347 chr1:204465584 NA -0.32 -6.7 -0.34 8.57e-11 Schizophrenia; LIHC cis rs6426558 0.537 rs694740 chr1:227293451 A/G cg10327440 chr1:227177885 CDC42BPA 0.43 6.57 0.33 1.82e-10 Neutrophil percentage of white cells; LIHC cis rs1003719 0.715 rs2835640 chr21:38537380 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs11190604 1.000 rs1417823 chr10:102227886 C/T cg07080220 chr10:102295463 HIF1AN -0.48 -7.05 -0.36 1.02e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17776563 0.887 rs11638658 chr15:89124610 C/G cg05013243 chr15:89149849 MIR1179 -0.4 -6.6 -0.34 1.6e-10 Thyroid hormone levels; LIHC cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg10802521 chr3:52805072 NEK4 -0.36 -5.74 -0.3 2.13e-8 Bipolar disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15248989 chr19:14682900 NDUFB7 0.52 7.02 0.35 1.17e-11 Lung function (FEV1/FVC); LIHC cis rs9814567 0.896 rs4435682 chr3:134344182 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.6 9.86 0.47 2.3e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7666738 0.606 rs13108868 chr4:99083753 C/T cg05340658 chr4:99064831 C4orf37 0.65 11.68 0.53 9.06e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23359048 chr12:2921757 ITFG2 0.5 6.63 0.34 1.29e-10 Lung function (FEV1/FVC); LIHC cis rs6912958 0.559 rs451465 chr6:88043372 C/T cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -7.32 -0.37 1.84e-12 Monocyte percentage of white cells; LIHC cis rs36051895 0.554 rs7856773 chr9:5204705 T/C cg02405213 chr9:5042618 JAK2 -0.64 -10.69 -0.5 3.32e-23 Pediatric autoimmune diseases; LIHC trans rs1432089 0.773 rs1030614 chr4:171786339 C/T cg02328223 chr3:127541927 MGLL -0.42 -6.09 -0.31 3.07e-9 Endometriosis; LIHC cis rs1799949 0.930 rs1554063 chr17:41287145 T/C cg25072359 chr17:41440525 NA 0.38 6.01 0.31 4.72e-9 Menopause (age at onset); LIHC cis rs116979167 0.630 rs56230603 chr7:105165268 A/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs8060686 0.641 rs3743735 chr16:68119555 G/A cg05110241 chr16:68378359 PRMT7 -0.6 -7.01 -0.35 1.32e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs4925386 0.681 rs2427295 chr20:60927431 G/A cg06026331 chr20:60912101 LAMA5 0.63 9.38 0.45 9.53e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs17292804 0.527 rs12887734 chr14:104046834 G/T cg19000871 chr14:103996768 TRMT61A -0.44 -7.34 -0.37 1.57e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg03806693 chr22:41940476 POLR3H 0.99 10.62 0.5 5.84e-23 Vitiligo; LIHC cis rs6752107 1.000 rs10165561 chr2:234172915 G/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.56 0.42 3.89e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7223966 0.960 rs2854222 chr17:61939015 C/T cg05941027 chr17:61774174 LIMD2 0.32 6.74 0.34 6.7e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7474896 0.583 rs10827818 chr10:38000856 T/C cg25427524 chr10:38739819 LOC399744 -0.5 -7.33 -0.37 1.63e-12 Obesity (extreme); LIHC cis rs11690935 0.632 rs11690807 chr2:172628120 G/A cg13550731 chr2:172543902 DYNC1I2 0.63 11.69 0.53 8.66e-27 Schizophrenia; LIHC cis rs16837677 0.649 rs16837622 chr1:156695504 C/T cg19377421 chr1:156697041 ISG20L2;C1orf66 -0.63 -7.46 -0.37 7e-13 Sjögren's syndrome; LIHC cis rs2455799 0.613 rs11920540 chr3:15854608 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.5 -0.38 5.71e-13 Mean platelet volume; LIHC cis rs12980942 1.000 rs7245398 chr19:41810644 A/G cg25627403 chr19:41769009 HNRNPUL1 0.49 6.21 0.32 1.56e-9 Coronary artery disease; LIHC cis rs9790314 0.586 rs34727114 chr3:161138929 A/C cg03342759 chr3:160939853 NMD3 -0.55 -8.38 -0.41 1.39e-15 Morning vs. evening chronotype; LIHC cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs4665809 1.000 rs11126364 chr2:26314515 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.99 -0.44 1.69e-17 Gut microbiome composition (summer); LIHC cis rs3741404 0.609 rs635139 chr11:63872210 A/G cg18225595 chr11:63971243 STIP1 0.46 7.34 0.37 1.57e-12 Platelet count; LIHC cis rs8078723 1.000 rs56922390 chr17:38157021 C/G cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.22 -0.45 3.13e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs950776 0.518 rs2292117 chr15:78834689 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.64 0.34 1.24e-10 Sudden cardiac arrest; LIHC cis rs1552244 0.816 rs13076197 chr3:10019773 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs1577917 0.681 rs4348284 chr6:86350394 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.22 -0.32 1.47e-9 Response to antipsychotic treatment; LIHC cis rs2153535 0.580 rs1410766 chr6:8525360 T/C cg23788917 chr6:8435910 SLC35B3 0.63 8.88 0.43 3.76e-17 Motion sickness; LIHC cis rs11761441 1.000 rs11761441 chr7:82377 G/A cg12845006 chr7:82380 NA 0.32 6.07 0.31 3.34e-9 Alzheimer's disease in APOE e4- carriers; LIHC trans rs62103177 0.525 rs8086024 chr18:77746623 A/G cg05926928 chr17:57297772 GDPD1 -0.55 -6.57 -0.33 1.88e-10 Opioid sensitivity; LIHC trans rs2744203 1.000 rs72610890 chr6:104657337 A/T cg27088726 chr16:83171155 CDH13 -0.45 -6.07 -0.31 3.35e-9 IgG glycosylation; LIHC cis rs7617773 0.780 rs7653336 chr3:48369464 T/A cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC cis rs7100689 0.784 rs10736341 chr10:82061206 C/G cg00277334 chr10:82204260 NA -0.55 -6.91 -0.35 2.43e-11 Post bronchodilator FEV1; LIHC cis rs1023500 0.573 rs1807494 chr22:42474138 C/G cg04733989 chr22:42467013 NAGA -0.66 -9.61 -0.46 1.62e-19 Schizophrenia; LIHC cis rs4819052 0.851 rs4819040 chr21:46659762 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.48 6.97 0.35 1.68e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg00750074 chr16:89608354 SPG7 -0.52 -8.49 -0.42 6.33e-16 Multiple myeloma (IgH translocation); LIHC cis rs6952808 0.729 rs35797753 chr7:1954914 G/A cg14004847 chr7:1930337 MAD1L1 -0.45 -6.25 -0.32 1.19e-9 Bipolar disorder and schizophrenia; LIHC cis rs6728642 0.561 rs58984980 chr2:97570759 T/A cg26665480 chr2:98280029 ACTR1B -0.57 -5.79 -0.3 1.57e-8 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs9309473 1.000 rs9653557 chr2:73795962 A/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg02951883 chr7:2050386 MAD1L1 -0.67 -10.82 -0.5 1.18e-23 Bipolar disorder and schizophrenia; LIHC cis rs11711311 0.955 rs10934247 chr3:113534941 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.31 -0.37 1.88e-12 IgG glycosylation; LIHC cis rs832187 0.629 rs7624403 chr3:63970077 G/T cg16258503 chr3:63850278 ATXN7;THOC7 -0.45 -6.41 -0.33 4.74e-10 Schizophrenia; LIHC cis rs9393692 0.572 rs4145878 chr6:26198046 A/T cg05868516 chr6:26286170 HIST1H4H 0.39 5.93 0.31 7.24e-9 Educational attainment; LIHC cis rs3824867 0.920 rs7105907 chr11:47450318 A/T cg20307385 chr11:47447363 PSMC3 -0.58 -7.89 -0.39 4.24e-14 Mean corpuscular hemoglobin; LIHC cis rs9303401 0.614 rs34683543 chr17:56520036 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.84 11.07 0.51 1.51e-24 Cognitive test performance; LIHC cis rs9911578 1.000 rs9901181 chr17:56964271 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.66e-17 Intelligence (multi-trait analysis); LIHC cis rs7106204 0.748 rs2403891 chr11:24213130 C/T ch.11.24196551F chr11:24239977 NA 0.76 10.16 0.48 2.29e-21 Response to Homoharringtonine (cytotoxicity); LIHC cis rs8023580 1.000 rs4984511 chr15:96704443 C/T cg01739960 chr15:96715164 NA 0.37 5.93 0.31 7.43e-9 Sex hormone-binding globulin levels; LIHC cis rs990171 0.506 rs6543107 chr2:102750730 A/T cg22835712 chr2:102737379 NA 0.57 8.76 0.43 9.21e-17 Lymphocyte counts; LIHC cis rs1005277 0.557 rs1854563 chr10:38434961 G/A cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs2857078 0.745 rs4793085 chr17:42320732 A/C cg08499158 chr17:42289980 UBTF 0.48 7.71 0.38 1.34e-13 Red cell distribution width;Reticulocyte count; LIHC cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg14004847 chr7:1930337 MAD1L1 -0.48 -6.92 -0.35 2.28e-11 Bipolar disorder and schizophrenia; LIHC cis rs763121 0.853 rs2267395 chr22:39113903 C/T cg06022373 chr22:39101656 GTPBP1 0.73 14.36 0.61 6.24e-37 Menopause (age at onset); LIHC cis rs11105298 0.891 rs10858900 chr12:89925081 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.3 -0.37 2.02e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs55823223 0.564 rs4572466 chr17:73846314 A/C cg08125733 chr17:73851984 WBP2 0.85 12.53 0.56 6.46e-30 Psoriasis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01216607 chr7:100860773 ZNHIT1;PLOD3 0.43 6.32 0.32 8.14e-10 Lung function (FEV1/FVC); LIHC cis rs904251 0.772 rs2776906 chr6:37431757 A/G cg01843034 chr6:37503916 NA -0.4 -6.46 -0.33 3.57e-10 Cognitive performance; LIHC trans rs208520 0.690 rs207119 chr6:66786408 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs66573146 0.831 rs56081162 chr4:6989718 C/T cg15105060 chr4:7024189 TBC1D14 -0.78 -6.26 -0.32 1.15e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs10506458 0.688 rs60936040 chr12:63416461 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.7 -10.28 -0.49 9.02e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.14e-11 Alzheimer's disease; LIHC cis rs2073300 1.000 rs6137961 chr20:23443102 G/T cg16736954 chr20:23401023 NAPB 0.53 5.84 0.3 1.22e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7107174 1.000 rs72931639 chr11:78036703 C/T cg02023728 chr11:77925099 USP35 0.5 9.47 0.46 4.85e-19 Testicular germ cell tumor; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg23521253 chr10:126653589 ZRANB1 -0.28 -6.4 -0.33 5.19e-10 Calcium levels; LIHC cis rs7715806 0.500 rs72633984 chr5:75005899 A/G cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs11098499 0.909 rs28632018 chr4:120386730 T/C cg25214090 chr10:38739885 LOC399744 0.61 9.99 0.48 8.49e-21 Corneal astigmatism; LIHC cis rs11018874 0.808 rs71471032 chr11:89888921 A/T cg05041596 chr11:89867385 NAALAD2 0.42 6.73 0.34 7.15e-11 White blood cell types; LIHC cis rs9359856 0.564 rs72913975 chr6:90387116 C/T cg13799429 chr6:90582589 CASP8AP2 -0.67 -6.3 -0.32 9.17e-10 Bipolar disorder; LIHC cis rs472402 0.580 rs3733773 chr5:6652252 G/A cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.46 -5.78 -0.3 1.71e-8 Response to amphetamines; LIHC cis rs11792861 0.926 rs12686736 chr9:111888739 A/G cg05043794 chr9:111880884 C9orf5 -0.28 -6.48 -0.33 3.15e-10 Menarche (age at onset); LIHC cis rs7187994 0.848 rs60566983 chr16:84774799 A/G cg07647771 chr16:84786436 USP10 -0.33 -6.27 -0.32 1.06e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs2204008 0.811 rs11520277 chr12:38359611 G/A cg26384229 chr12:38710491 ALG10B 0.57 7.88 0.39 4.37e-14 Bladder cancer; LIHC cis rs876084 0.505 rs9297614 chr8:121105444 C/T cg06265175 chr8:121136014 COL14A1 0.49 7.93 0.39 3.09e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9394841 0.667 rs12661667 chr6:41792545 C/T cg08135965 chr6:41755394 TOMM6 0.43 5.75 0.3 2.01e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs4629710 0.568 rs67021539 chr6:131552900 A/G cg12606694 chr6:131520996 AKAP7 0.62 7.33 0.37 1.64e-12 Multiple myeloma (IgH translocation); LIHC cis rs17539620 0.624 rs4566892 chr6:154837346 C/T cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs854765 0.647 rs8066764 chr17:17974668 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.38 7.14 0.36 5.58e-12 Total body bone mineral density; LIHC cis rs6430585 1.000 rs6732236 chr2:136501509 T/G cg07169764 chr2:136633963 MCM6 1.02 13.78 0.6 1.1e-34 Corneal structure; LIHC cis rs57502260 0.704 rs17149179 chr11:68351722 C/T cg20283391 chr11:68216788 NA -0.51 -6.08 -0.31 3.28e-9 Total body bone mineral density (age 45-60); LIHC cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs13191362 1.000 rs13204439 chr6:163015358 A/C cg06582575 chr6:163149167 PACRG;PARK2 -0.61 -5.95 -0.31 6.78e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10489202 0.865 rs744168 chr1:168094079 G/T cg17859187 chr1:168147929 TIPRL 0.6 7.6 0.38 2.94e-13 Schizophrenia; LIHC cis rs6570726 0.935 rs365658 chr6:145844588 C/T cg23711669 chr6:146136114 FBXO30 0.55 9.93 0.47 1.41e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs10256972 0.605 rs10251094 chr7:1017083 G/T cg24642844 chr7:1081250 C7orf50 -0.74 -6.32 -0.32 8.23e-10 Longevity;Endometriosis; LIHC cis rs10504229 0.953 rs6985942 chr8:58173412 T/C cg21724239 chr8:58056113 NA 0.46 6.08 0.31 3.23e-9 Developmental language disorder (linguistic errors); LIHC trans rs4014195 0.521 rs12576996 chr11:65580638 G/T cg17712092 chr4:129076599 LARP1B 0.54 6.56 0.33 1.94e-10 Glomerular filtration rate (creatinine);Chronic kidney disease; LIHC cis rs7927592 0.913 rs67947146 chr11:68314980 C/T cg20283391 chr11:68216788 NA -0.52 -7.85 -0.39 5.44e-14 Total body bone mineral density; LIHC cis rs1801251 1.000 rs895430 chr2:233725483 C/A cg25237894 chr2:233734115 C2orf82 -0.58 -11.42 -0.53 8.16e-26 Coronary artery disease; LIHC cis rs2710642 0.583 rs7421841 chr2:62880765 G/A cg17519650 chr2:63277830 OTX1 0.5 7.26 0.37 2.63e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs6840360 1.000 rs3749563 chr4:152596508 T/C cg22705602 chr4:152727874 NA -0.29 -6.29 -0.32 9.49e-10 Intelligence (multi-trait analysis); LIHC cis rs4969178 0.600 rs4969184 chr17:76393413 G/A cg05887092 chr17:76393375 PGS1 0.35 6.8 0.35 4.73e-11 HDL cholesterol levels; LIHC cis rs7917772 0.582 rs7075269 chr10:104365724 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.81 0.39 6.99e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs929354 0.713 rs10085650 chr7:156993413 T/C cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs7264396 0.563 rs11906854 chr20:34383634 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.57 -8.03 -0.4 1.63e-14 Total cholesterol levels; LIHC cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4718428 0.705 rs13220977 chr7:66337648 A/T cg18252515 chr7:66147081 NA 0.66 8.91 0.43 2.98e-17 Corneal structure; LIHC cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg16606324 chr3:10149918 C3orf24 0.54 5.9 0.3 8.94e-9 Alzheimer's disease; LIHC cis rs4803468 0.967 rs11083619 chr19:41913267 A/C cg09537434 chr19:41945824 ATP5SL -1.01 -21.33 -0.76 8.44e-65 Height; LIHC cis rs1800682 0.528 rs3903454 chr10:90743434 A/T cg03111039 chr10:90751583 FAS;ACTA2 0.74 11.8 0.54 3.56e-27 Chronic lymphocytic leukemia; LIHC cis rs2066819 1.000 rs57870697 chr12:56752874 A/G cg26734620 chr12:56694298 CS 1.21 10.14 0.48 2.67e-21 Psoriasis vulgaris; LIHC trans rs9747201 0.963 rs11077982 chr17:80147377 G/C cg07393940 chr7:158741817 NA 0.56 6.73 0.34 7.12e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11764590 0.724 rs55669426 chr7:2090129 G/C cg23422044 chr7:1970798 MAD1L1 -0.56 -8.76 -0.43 8.91e-17 Neuroticism; LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg02951883 chr7:2050386 MAD1L1 -0.72 -12.07 -0.55 3.34e-28 Bipolar disorder and schizophrenia; LIHC cis rs1707322 1.000 rs6676982 chr1:46275401 A/T cg06784218 chr1:46089804 CCDC17 0.35 6.19 0.32 1.71e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.9 9.24 0.45 2.64e-18 Platelet count; LIHC cis rs2032447 0.531 rs428469 chr6:25898624 G/A cg15691649 chr6:25882328 NA -0.97 -12.43 -0.56 1.65e-29 Intelligence (multi-trait analysis); LIHC cis rs7961581 0.576 rs1798076 chr12:71589671 A/G cg05756094 chr12:71608604 NA -0.35 -5.85 -0.3 1.15e-8 Type 2 diabetes; LIHC cis rs2274273 0.870 rs59629906 chr14:55781189 T/C cg01864836 chr14:55583639 NA -0.37 -6.55 -0.33 2.17e-10 Protein biomarker; LIHC cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 9.22 0.45 3.2e-18 Platelet count; LIHC cis rs713477 0.967 rs4901570 chr14:55915249 T/C cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.45e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs12887734 0.546 rs4906376 chr14:104272165 A/C cg24130564 chr14:104152367 KLC1 -0.44 -7.04 -0.36 1.07e-11 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2032447 0.507 rs478349 chr6:25894057 T/C cg15691649 chr6:25882328 NA -0.97 -12.64 -0.56 2.6e-30 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs523522 0.571 rs11065120 chr12:120875456 C/T cg12219531 chr12:120966889 COQ5 0.49 8.16 0.4 6.53e-15 High light scatter reticulocyte count; LIHC cis rs801193 1.000 rs7782320 chr7:66177098 C/T cg14393609 chr7:65229607 NA 0.37 5.78 0.3 1.71e-8 Aortic root size; LIHC cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg09913183 chr17:42254507 C17orf65;ASB16 0.67 10.46 0.49 2.14e-22 Total body bone mineral density; LIHC cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg18252515 chr7:66147081 NA 1.29 17.4 0.69 4.95e-49 Diabetic kidney disease; LIHC trans rs1814175 0.645 rs10839382 chr11:49823172 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.95 0.35 1.83e-11 Height; LIHC cis rs9309473 0.555 rs2901437 chr2:73597024 T/G cg20560298 chr2:73613845 ALMS1 -0.45 -7.39 -0.37 1.14e-12 Metabolite levels; LIHC cis rs853679 0.517 rs34716816 chr6:28046169 C/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs10751667 1.000 rs10902233 chr11:925510 A/G ch.11.42038R chr11:967971 AP2A2 0.58 10.63 0.5 5.59e-23 Alzheimer's disease (late onset); LIHC cis rs10768122 0.642 rs3847619 chr11:35360747 C/T cg13971030 chr11:35366721 SLC1A2 -0.35 -5.76 -0.3 1.9e-8 Vitiligo; LIHC cis rs950776 0.616 rs3743077 chr15:78894896 C/T cg06917634 chr15:78832804 PSMA4 0.67 9.11 0.44 7.27e-18 Sudden cardiac arrest; LIHC cis rs208520 0.802 rs4710314 chr6:66883656 G/A cg07460842 chr6:66804631 NA -0.76 -8.34 -0.41 1.89e-15 Exhaled nitric oxide output; LIHC cis rs7224737 0.956 rs7208907 chr17:40284783 C/T cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs9814567 1.000 rs9851441 chr3:134315091 C/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg02782426 chr3:40428986 ENTPD3 0.33 6.1 0.31 2.87e-9 Renal cell carcinoma; LIHC cis rs1048238 0.506 rs12023422 chr1:16187625 G/A cg00529422 chr1:16285251 ZBTB17 -0.34 -6.43 -0.33 4.37e-10 Systolic blood pressure; LIHC cis rs1008375 0.863 rs4590022 chr4:17614434 T/C cg02297831 chr4:17616191 MED28 0.49 7.61 0.38 2.63e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -10.41 -0.49 3.04e-22 Platelet count; LIHC cis rs722599 0.683 rs11848876 chr14:75224626 C/G cg08847533 chr14:75593920 NEK9 0.5 7.65 0.38 2.05e-13 IgG glycosylation; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs10751667 0.643 rs7396407 chr11:929374 A/T cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC cis rs10751667 1.000 rs11246359 chr11:967943 T/C cg10932868 chr11:921992 NA 0.36 6.77 0.34 5.46e-11 Alzheimer's disease (late onset); LIHC cis rs798554 0.757 rs2533879 chr7:2859847 G/A cg19346786 chr7:2764209 NA -0.49 -7.34 -0.37 1.53e-12 Height; LIHC cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg22963979 chr7:1858916 MAD1L1 -0.42 -6.8 -0.35 4.59e-11 Schizophrenia; LIHC cis rs12497850 0.931 rs7627404 chr3:48819668 A/C cg06212747 chr3:49208901 KLHDC8B 0.56 7.23 0.36 3.26e-12 Parkinson's disease; LIHC cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg16325326 chr1:53192061 ZYG11B -0.4 -6.75 -0.34 6.24e-11 Monocyte count; LIHC cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.73 7.41 0.37 1.02e-12 Platelet count; LIHC cis rs6912958 0.559 rs242279 chr6:88048191 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.94 0.51 4.23e-24 Monocyte percentage of white cells; LIHC cis rs17106184 1.000 rs77701130 chr1:51232628 G/C cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs1707322 0.964 rs785499 chr1:46592420 G/A cg03146154 chr1:46216737 IPP -0.46 -7.28 -0.37 2.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg09367891 chr1:107599246 PRMT6 0.69 11.5 0.53 4.32e-26 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs911555 0.662 rs4906322 chr14:103879032 A/G cg17675199 chr6:35436792 RPL10A -0.43 -8.59 -0.42 3.03e-16 Intelligence (multi-trait analysis); LIHC cis rs7523273 0.526 rs3849274 chr1:208021557 T/A cg22525895 chr1:207977042 MIR29B2 -0.61 -9.3 -0.45 1.7e-18 Schizophrenia; LIHC trans rs11098499 0.754 rs11724409 chr4:120252361 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.25 0.41 3.48e-15 Corneal astigmatism; LIHC cis rs2153535 0.580 rs763376 chr6:8492776 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs2070488 0.965 rs2126534 chr3:38445165 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.55 0.64 1.28e-41 Electrocardiographic conduction measures; LIHC cis rs9649213 0.559 rs56997921 chr7:98009224 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.56 -9.92 -0.47 1.46e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs5769765 0.955 rs5770750 chr22:50276828 A/G cg26441486 chr22:50317300 CRELD2 -0.35 -6.32 -0.32 7.96e-10 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04297576 chr16:85588660 NA -0.48 -6.15 -0.32 2.15e-9 Systolic blood pressure; LIHC cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg19318889 chr4:1322082 MAEA 0.46 6.49 0.33 3.11e-10 Obesity-related traits; LIHC trans rs3112255 0.967 rs1606552 chr2:101304053 T/G cg06958034 chr1:23346203 KDM1A -0.46 -6.06 -0.31 3.55e-9 Intelligence (multi-trait analysis); LIHC cis rs6066825 0.532 rs6012506 chr20:47285637 A/G cg18078177 chr20:47281410 PREX1 0.45 7.5 0.38 5.57e-13 Colorectal cancer; LIHC cis rs1816752 0.905 rs9511249 chr13:24999595 G/A cg22771759 chr13:24902376 NA 0.31 6.36 0.33 6.62e-10 Obesity-related traits; LIHC cis rs9625935 0.536 rs9608819 chr22:30260809 A/C cg01021169 chr22:30184971 ASCC2 0.37 6.3 0.32 8.93e-10 Tonsillectomy; LIHC cis rs875971 1.000 rs937495 chr7:65779798 A/G cg11764359 chr7:65958608 NA -0.92 -17.1 -0.68 8.54e-48 Aortic root size; LIHC cis rs12478296 0.901 rs6731775 chr2:242999443 T/C cg18898632 chr2:242989856 NA -0.47 -6.48 -0.33 3.26e-10 Obesity-related traits; LIHC trans rs7677751 0.806 rs7673027 chr4:55096180 T/A cg17183009 chr3:120277827 NA 0.52 6.11 0.31 2.73e-9 Corneal astigmatism; LIHC cis rs2710642 0.678 rs11125946 chr2:63298150 C/T cg17519650 chr2:63277830 OTX1 -0.51 -7.44 -0.37 8.48e-13 LDL cholesterol levels;LDL cholesterol; LIHC cis rs965469 0.762 rs6515783 chr20:3245006 T/C cg25506879 chr20:3388711 C20orf194 -0.51 -6.24 -0.32 1.3e-9 IFN-related cytopenia; LIHC cis rs2072499 0.900 rs2248080 chr1:156195971 T/A cg25208724 chr1:156163844 SLC25A44 0.84 13.34 0.58 5.86e-33 Testicular germ cell tumor; LIHC trans rs2727020 0.521 rs1909220 chr11:49572109 T/C cg03929089 chr4:120376271 NA -0.69 -10.15 -0.48 2.49e-21 Coronary artery disease; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg06267636 chr1:156308293 CCT3;C1orf182 -0.43 -6.36 -0.33 6.62e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs11098499 0.863 rs3775854 chr4:120471971 C/T cg09307838 chr4:120376055 NA 0.75 11.33 0.52 1.79e-25 Corneal astigmatism; LIHC cis rs477895 1.000 rs66968227 chr11:64070930 T/C cg04317338 chr11:64019027 PLCB3 0.87 8.53 0.42 4.82e-16 Mean platelet volume; LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg25897951 chr4:1244024 CTBP1;C4orf42 -0.43 -6.14 -0.32 2.24e-9 Longevity; LIHC cis rs151997 0.925 rs27570 chr5:50191974 G/A cg06027927 chr5:50259733 NA 0.57 7.7 0.38 1.53e-13 Callous-unemotional behaviour; LIHC cis rs2282802 0.651 rs13353827 chr5:139654537 T/C cg26211634 chr5:139558579 C5orf32 0.39 6.03 0.31 4.29e-9 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.904 rs801426 chr17:37441109 C/T cg03013999 chr17:37608204 MED1 -0.35 -5.93 -0.31 7.26e-9 Glomerular filtration rate (creatinine); LIHC cis rs3796619 1.000 rs4974638 chr4:1099201 G/A cg27284194 chr4:1044797 NA 0.64 10.65 0.5 4.42e-23 Recombination rate (males); LIHC cis rs6750047 0.719 rs336035 chr2:38261467 A/G cg07380506 chr2:38303506 CYP1B1 -0.49 -5.94 -0.31 6.93e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs3008870 0.755 rs3736905 chr1:67392614 A/G cg02640540 chr1:67518911 SLC35D1 0.41 6.42 0.33 4.48e-10 Lymphocyte percentage of white cells; LIHC cis rs6088580 0.524 rs7269596 chr20:33229063 T/C cg07148914 chr20:33460835 GGT7 -0.5 -7.14 -0.36 5.64e-12 Glomerular filtration rate (creatinine); LIHC cis rs798766 0.909 rs744658 chr4:1755074 C/T cg21231739 chr4:1642635 FAM53A -0.37 -6.0 -0.31 5.04e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs4700695 1.000 rs153389 chr5:65422729 C/T cg21114390 chr5:65439923 SFRS12 -0.52 -7.08 -0.36 8.22e-12 Facial morphology (factor 19); LIHC cis rs477895 0.713 rs11607165 chr11:63963947 T/G cg05555928 chr11:63887634 MACROD1 0.51 6.6 0.34 1.59e-10 Mean platelet volume; LIHC cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09068447 chr15:34502498 C15orf29 0.45 6.68 0.34 9.45e-11 Pancreatic cancer; LIHC cis rs4700695 0.764 rs251278 chr5:65381826 G/A cg21114390 chr5:65439923 SFRS12 -0.5 -6.89 -0.35 2.67e-11 Facial morphology (factor 19); LIHC cis rs2839627 0.513 rs7282879 chr21:44286525 C/T cg18192155 chr21:44258298 NA 0.4 6.12 0.31 2.61e-9 Information processing speed; LIHC cis rs7395581 0.918 rs61896050 chr11:47309063 T/C cg25783544 chr11:47291846 MADD 0.43 6.27 0.32 1.1e-9 HDL cholesterol; LIHC trans rs2832191 0.716 rs1888439 chr21:30454457 A/G cg14791747 chr16:20752902 THUMPD1 -0.47 -6.48 -0.33 3.19e-10 Dental caries; LIHC cis rs40363 0.645 rs250629 chr16:3525431 C/A cg00484396 chr16:3507460 NAT15 0.44 7.76 0.39 9.9e-14 Tuberculosis; LIHC trans rs11098499 1.000 rs6837898 chr4:120179154 C/T cg25214090 chr10:38739885 LOC399744 0.51 7.74 0.39 1.1e-13 Corneal astigmatism; LIHC cis rs713477 0.935 rs12888181 chr14:55906082 A/C cg13175173 chr14:55914753 NA -0.35 -8.13 -0.4 7.98e-15 Pediatric bone mineral content (femoral neck); LIHC trans rs13113518 0.729 rs13120134 chr4:56281320 A/G cg15358633 chr12:38710606 ALG10B 0.43 6.05 0.31 3.76e-9 Height; LIHC cis rs7412746 0.611 rs752376 chr1:150941381 C/T cg18016565 chr1:150552671 MCL1 0.49 9.28 0.45 1.95e-18 Melanoma; LIHC cis rs4665809 1.000 rs10048648 chr2:26320315 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.84 -0.43 5.27e-17 Gut microbiome composition (summer); LIHC cis rs10493773 0.775 rs12564080 chr1:86196586 A/C cg17807903 chr1:86174739 ZNHIT6 -0.55 -10.16 -0.48 2.21e-21 Urate levels in overweight individuals; LIHC cis rs10540 1.000 rs61876339 chr11:495283 T/C cg03576123 chr11:487126 PTDSS2 -1.11 -8.28 -0.41 2.82e-15 Body mass index; LIHC cis rs4076764 0.914 rs6704467 chr1:163364512 A/G cg24596788 chr1:163392923 NA -0.2 -6.18 -0.32 1.82e-9 Motion sickness; LIHC cis rs7123876 0.830 rs59311588 chr11:72435996 A/G cg03713592 chr11:72463424 ARAP1 0.57 6.48 0.33 3.26e-10 Body mass index; LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs11792861 0.926 rs11787878 chr9:111866749 C/T cg13535736 chr9:111863775 C9orf5 -0.38 -5.78 -0.3 1.69e-8 Menarche (age at onset); LIHC cis rs9325144 0.534 rs1843866 chr12:38703160 G/T cg26384229 chr12:38710491 ALG10B 0.6 8.38 0.41 1.35e-15 Morning vs. evening chronotype; LIHC cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg21782813 chr7:2030301 MAD1L1 -0.5 -8.54 -0.42 4.44e-16 Bipolar disorder and schizophrenia; LIHC cis rs11098499 0.954 rs10006877 chr4:120242793 C/T cg09307838 chr4:120376055 NA 0.75 11.39 0.52 1.1e-25 Corneal astigmatism; LIHC cis rs4319547 0.661 rs10773172 chr12:122939655 G/A cg05707623 chr12:122985044 ZCCHC8 -0.58 -7.95 -0.39 2.74e-14 Body mass index; LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg13395646 chr4:1353034 KIAA1530 -0.49 -7.63 -0.38 2.29e-13 Obesity-related traits; LIHC cis rs8017423 0.967 rs28424204 chr14:90705669 G/C cg14092571 chr14:90743983 NA -0.37 -5.88 -0.3 9.66e-9 Mortality in heart failure; LIHC cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg05552183 chr6:42928497 GNMT 0.68 10.21 0.48 1.55e-21 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs17685 0.753 rs10264760 chr7:75749694 A/G cg19862616 chr7:65841803 NCRNA00174 0.91 18.75 0.71 1.96e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11758351 1.000 rs80095925 chr6:26184942 C/T cg16070018 chr6:26224392 HIST1H3E 0.65 7.79 0.39 7.91e-14 Gout;Renal underexcretion gout; LIHC cis rs2153535 0.580 rs1932283 chr6:8477661 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.5 0.42 5.86e-16 Motion sickness; LIHC trans rs10506458 0.834 rs73127067 chr12:63390333 G/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.43 -0.49 2.72e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs9389248 0.690 rs728030 chr6:135246294 G/T cg22676075 chr6:135203613 NA -0.39 -5.91 -0.3 8.3e-9 High light scatter reticulocyte percentage of red cells; LIHC cis rs10193935 0.901 rs55978605 chr2:42573402 C/A cg27598129 chr2:42591480 NA -0.75 -11.86 -0.54 2.13e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs988712 0.705 rs1829469 chr11:27730556 A/G cg18117895 chr11:27722066 BDNF 0.51 7.07 0.36 8.55e-12 Obesity; LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.38 -8.41 -0.41 1.13e-15 Calcium levels; LIHC cis rs9896052 0.580 rs6501809 chr17:73467274 C/T cg25649188 chr17:73499917 CASKIN2 0.5 7.43 0.37 8.98e-13 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg16405210 chr4:1374714 KIAA1530 0.86 13.68 0.59 2.69e-34 Longevity; LIHC cis rs7539409 0.651 rs970457 chr1:84296540 C/T cg10977910 chr1:84465055 TTLL7 0.69 7.0 0.35 1.4e-11 Alzheimer's disease; LIHC cis rs6062302 0.548 rs6089940 chr20:62252695 C/T cg06363034 chr20:62225388 GMEB2 -0.45 -7.77 -0.39 9.21e-14 Glioblastoma; LIHC cis rs9733 0.565 rs7524620 chr1:150616699 C/T cg18016565 chr1:150552671 MCL1 -0.56 -11.02 -0.51 2.32e-24 Tonsillectomy; LIHC cis rs1866706 0.896 rs2083440 chr11:12865839 C/T cg25843174 chr11:12811716 TEAD1 -0.3 -6.26 -0.32 1.12e-9 Intelligence (multi-trait analysis); LIHC cis rs270601 0.909 rs2569265 chr5:131704519 T/C cg24060327 chr5:131705240 SLC22A5 0.78 12.16 0.55 1.58e-28 Acylcarnitine levels; LIHC cis rs17253792 0.822 rs77315200 chr14:56072643 C/A cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs2842992 0.672 rs7738253 chr6:160193917 G/T cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.35 0.41 1.78e-15 Age-related macular degeneration (geographic atrophy); LIHC cis rs858239 0.601 rs11984129 chr7:23152677 A/G cg23682824 chr7:23144976 KLHL7 0.4 6.02 0.31 4.4e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs1949733 0.554 rs4259044 chr4:8536188 A/G cg11789530 chr4:8429930 ACOX3 -0.52 -7.45 -0.37 7.49e-13 Response to antineoplastic agents; LIHC cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg07092213 chr7:1199455 ZFAND2A -0.43 -6.36 -0.33 6.64e-10 Longevity;Endometriosis; LIHC cis rs12594515 0.904 rs8032875 chr15:45998010 A/C cg06207120 chr15:45996521 NA 0.31 5.83 0.3 1.27e-8 Waist circumference;Weight; LIHC cis rs753778 0.628 rs11579 chr8:142205132 G/A cg18755752 chr8:142205143 DENND3 -0.34 -6.28 -0.32 1.02e-9 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09970552 chr11:57520334 BTBD18 0.49 6.65 0.34 1.18e-10 Hepatitis; LIHC cis rs2108622 0.727 rs55954696 chr19:15981805 A/G cg13772218 chr19:15982569 NA 0.37 7.83 0.39 6.2e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs9457247 1.000 rs400176 chr6:167406238 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.04e-24 Crohn's disease; LIHC cis rs3008870 0.727 rs11208971 chr1:67383901 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.69 0.5 3.44e-23 Lymphocyte percentage of white cells; LIHC trans rs916888 0.821 rs199504 chr17:44861003 C/T cg07870213 chr5:140052090 DND1 -1.01 -10.33 -0.49 5.92e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg03806693 chr22:41940476 POLR3H 1.12 13.03 0.58 8.92e-32 Vitiligo; LIHC cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg23978390 chr7:1156363 C7orf50 0.66 10.34 0.49 5.55e-22 Longevity;Endometriosis; LIHC cis rs7412746 0.611 rs10888398 chr1:150886782 A/G cg15448220 chr1:150897856 SETDB1 -0.4 -6.25 -0.32 1.19e-9 Melanoma; LIHC cis rs1075232 0.826 rs60333545 chr15:31807319 G/C cg01030201 chr15:31746330 NA -0.85 -6.66 -0.34 1.08e-10 Survival in colorectal cancer (non-distant metastatic); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.14.1056569F chr14:73577815 RBM25 -0.32 -6.53 -0.33 2.35e-10 Cognitive function; LIHC trans rs7618501 0.501 rs35275715 chr3:49959148 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.76 0.34 5.98e-11 Intelligence (multi-trait analysis); LIHC cis rs74181299 0.855 rs2723066 chr2:65279321 T/G cg05010058 chr2:65284262 CEP68 0.41 6.86 0.35 3.18e-11 Pulse pressure; LIHC cis rs875971 0.862 rs6460293 chr7:65810192 C/A cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs7223966 1.000 rs2854219 chr17:61942682 C/T cg05941027 chr17:61774174 LIMD2 0.37 7.78 0.39 8.47e-14 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1707322 1.000 rs1707303 chr1:46598273 A/C cg06784218 chr1:46089804 CCDC17 -0.37 -6.53 -0.33 2.39e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1215050 0.791 rs6532702 chr4:98766641 C/T cg05340658 chr4:99064831 C4orf37 0.41 5.97 0.31 6e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2439831 0.850 rs12441127 chr15:44021175 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.35 0.41 1.67e-15 Lung cancer in ever smokers; LIHC cis rs911119 1.000 rs35488434 chr20:23620401 T/C cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs10504229 0.679 rs72649119 chr8:58040301 T/C cg20607798 chr8:58055168 NA 0.46 6.3 0.32 9.07e-10 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.619 rs7973869 chr12:122874284 G/C cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.15 -0.36 5.15e-12 Body mass index; LIHC cis rs7246657 0.943 rs10405407 chr19:37839164 C/T cg23950597 chr19:37808831 NA -0.44 -5.97 -0.31 5.93e-9 Coronary artery calcification; LIHC cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9457247 1.000 rs400837 chr6:167411008 T/C cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC cis rs344364 0.511 rs2906912 chr16:1953151 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.57 -7.51 -0.38 5.04e-13 Glomerular filtration rate in chronic kidney disease; LIHC cis rs1023500 0.551 rs133379 chr22:42468535 A/G cg15557168 chr22:42548783 NA -0.45 -6.98 -0.35 1.53e-11 Schizophrenia; LIHC cis rs2153535 0.580 rs1034273 chr6:8468145 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs16912059 0.590 rs7128158 chr11:24273521 A/T ch.11.24196551F chr11:24239977 NA -0.73 -6.05 -0.31 3.87e-9 Thrombin-antithrombin complex levels in ischemic stroke; LIHC cis rs4555082 0.874 rs2816613 chr14:105726367 C/T cg06808227 chr14:105710500 BRF1 -0.55 -7.21 -0.36 3.58e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg07308232 chr7:1071921 C7orf50 -0.46 -7.25 -0.36 2.82e-12 Longevity;Endometriosis; LIHC cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.49 7.61 0.38 2.65e-13 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.06 0.55 3.69e-28 Prudent dietary pattern; LIHC cis rs1190552 0.747 rs9324048 chr14:102881323 T/G cg10241871 chr14:102965420 TECPR2 0.4 6.05 0.31 3.72e-9 Blood protein levels; LIHC cis rs769267 0.859 rs2916076 chr19:19545990 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.03 0.31 4.17e-9 Tonsillectomy; LIHC cis rs116095464 0.558 rs10077076 chr5:231940 C/T cg22496380 chr5:211416 CCDC127 -1.02 -10.51 -0.49 1.47e-22 Breast cancer; LIHC cis rs2279817 0.863 rs6672069 chr1:18013835 G/C cg21791023 chr1:18019539 ARHGEF10L -0.69 -8.38 -0.41 1.42e-15 Neuroticism; LIHC cis rs769267 0.965 rs2074303 chr19:19381755 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.62 9.55 0.46 2.58e-19 Tonsillectomy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25954914 chr2:54785183 SPTBN1 -0.42 -6.15 -0.32 2.16e-9 Pancreatic cancer; LIHC cis rs3862260 0.509 rs10802124 chr1:120164252 G/A cg16322792 chr1:120165303 ZNF697 0.52 9.46 0.46 5.04e-19 Systemic lupus erythematosus; LIHC cis rs10876993 0.890 rs774891 chr12:58068571 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.29 -0.32 9.98e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg08645402 chr16:4508243 NA 0.4 7.53 0.38 4.49e-13 Schizophrenia; LIHC cis rs826838 0.806 rs826873 chr12:39121305 G/A cg13010199 chr12:38710504 ALG10B -0.42 -5.99 -0.31 5.26e-9 Heart rate; LIHC cis rs1801251 0.778 rs2592115 chr2:233736349 C/T cg25237894 chr2:233734115 C2orf82 -0.6 -12.21 -0.55 1.02e-28 Coronary artery disease; LIHC cis rs965469 0.779 rs2236109 chr20:3286439 C/A cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs35146811 0.844 rs13232115 chr7:99670932 T/C cg13334819 chr7:99746414 C7orf59 -0.55 -7.93 -0.39 3.23e-14 Coronary artery disease; LIHC cis rs644799 0.562 rs669973 chr11:95571839 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.67 10.99 0.51 3.01e-24 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11586313 0.507 rs6658967 chr1:152870372 C/G cg07796016 chr1:152779584 LCE1C -0.46 -7.13 -0.36 6.08e-12 Vitamin D levels; LIHC cis rs2637030 0.586 rs1030228 chr5:52842569 A/G cg06476337 chr5:52856530 NDUFS4 0.38 6.22 0.32 1.43e-9 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs35110281 0.807 rs2838328 chr21:45023234 G/C cg01579765 chr21:45077557 HSF2BP -0.33 -6.2 -0.32 1.61e-9 Mean corpuscular volume; LIHC cis rs763121 0.889 rs9610971 chr22:38910810 C/T cg06022373 chr22:39101656 GTPBP1 0.63 10.3 0.49 7.82e-22 Menopause (age at onset); LIHC cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg08645402 chr16:4508243 NA 0.4 7.56 0.38 3.67e-13 Schizophrenia; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.56 0.62 1.09e-37 Prudent dietary pattern; LIHC cis rs2795502 1.000 rs2795503 chr10:43347224 T/A cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs6598955 0.950 rs6700455 chr1:26545864 T/C cg04990556 chr1:26633338 UBXN11 0.75 11.95 0.54 1e-27 Obesity-related traits; LIHC cis rs2816062 0.813 rs2816040 chr1:18889536 C/T cg18795169 chr1:18902165 NA 0.74 16.13 0.66 6.35e-44 Urate levels in lean individuals; LIHC cis rs4555082 0.830 rs3803319 chr14:105752458 G/A cg10792982 chr14:105748885 BRF1 0.45 6.06 0.31 3.66e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs6912958 0.559 rs1201409 chr6:88055264 T/C cg08069147 chr6:88032118 GJB7;C6orf162 0.58 10.91 0.51 5.47e-24 Monocyte percentage of white cells; LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg14709524 chr16:89940631 TCF25 0.51 6.44 0.33 4.1e-10 Skin colour saturation; LIHC cis rs12368653 0.666 rs1050045 chr12:58115271 A/G cg12615879 chr12:58013172 SLC26A10 0.33 6.74 0.34 6.62e-11 Multiple sclerosis; LIHC cis rs754466 0.580 rs10430529 chr10:79582623 C/A cg17075019 chr10:79541650 NA -0.8 -12.28 -0.55 5.67e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs7618501 0.699 rs3733135 chr3:49939587 G/A cg21659725 chr3:3221576 CRBN 0.72 11.09 0.51 1.24e-24 Intelligence (multi-trait analysis); LIHC cis rs9394841 0.692 rs9381097 chr6:41847800 A/G cg08135965 chr6:41755394 TOMM6 -0.45 -6.01 -0.31 4.75e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs116095464 0.867 rs7726582 chr5:215349 C/G cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.09 0.55 2.92e-28 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg11764359 chr7:65958608 NA 0.56 5.96 0.31 6.14e-9 Diabetic kidney disease; LIHC cis rs780094 0.544 rs780110 chr2:27685388 G/A cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.75 -0.3 2.03e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs3809566 0.526 rs35829897 chr15:63334688 G/C cg05507819 chr15:63340323 TPM1 -0.65 -5.79 -0.3 1.59e-8 Platelet count; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg09367891 chr1:107599246 PRMT6 0.68 11.48 0.53 4.92e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6964587 1.000 rs55745934 chr7:91670998 T/C cg17063962 chr7:91808500 NA 1.01 19.44 0.72 3.05e-57 Breast cancer; LIHC cis rs35110281 0.591 rs86139 chr21:44932802 G/A cg04455712 chr21:45112962 RRP1B 0.44 7.48 0.37 6.45e-13 Mean corpuscular volume; LIHC cis rs7395581 0.918 rs7120957 chr11:47340649 A/G cg26139080 chr11:47293733 MADD -0.5 -8.45 -0.42 8.46e-16 HDL cholesterol; LIHC cis rs55665837 0.540 rs12416696 chr11:14790889 G/A cg00085434 chr11:14927489 NA 0.41 5.86 0.3 1.06e-8 Vitamin D levels; LIHC cis rs7772486 0.597 rs1970306 chr6:146154543 A/G cg13319975 chr6:146136371 FBXO30 -0.57 -9.09 -0.44 8.01e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs911119 1.000 rs6515375 chr20:23610841 G/A cg16589663 chr20:23618590 CST3 0.74 7.5 0.38 5.58e-13 Chronic kidney disease; LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg11965913 chr1:205819406 PM20D1 0.62 9.02 0.44 1.42e-17 Menarche (age at onset); LIHC cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg03517284 chr6:25882590 NA -0.67 -8.58 -0.42 3.37e-16 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05788437 chr3:197476880 FYTTD1;KIAA0226 -0.52 -7.82 -0.39 6.46e-14 Cognitive function; LIHC cis rs11098499 0.954 rs12507964 chr4:120413061 T/A cg09307838 chr4:120376055 NA 0.77 12.34 0.56 3.42e-29 Corneal astigmatism; LIHC cis rs72781680 0.904 rs72796340 chr2:24143622 T/A cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC trans rs1814175 0.867 rs7926002 chr11:49616018 A/G cg03929089 chr4:120376271 NA -0.88 -16.98 -0.68 2.43e-47 Height; LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg04267008 chr7:1944627 MAD1L1 -0.69 -11.49 -0.53 4.61e-26 Bipolar disorder and schizophrenia; LIHC cis rs6690583 0.697 rs10782537 chr1:85484473 C/T cg22153463 chr1:85462885 MCOLN2 -0.6 -9.18 -0.44 4.15e-18 Serum sulfate level; LIHC cis rs7937682 0.889 rs559482 chr11:111497902 G/A cg09085632 chr11:111637200 PPP2R1B -1.03 -12.24 -0.55 7.9e-29 Primary sclerosing cholangitis; LIHC cis rs8062405 0.755 rs4788074 chr16:28593597 A/G cg00204512 chr16:28754710 NA -0.38 -6.65 -0.34 1.13e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9527 0.662 rs743575 chr10:104594906 T/G cg15744005 chr10:104629667 AS3MT -0.35 -6.42 -0.33 4.59e-10 Arsenic metabolism; LIHC cis rs11971779 0.564 rs6467841 chr7:139066092 T/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs9359856 0.564 rs17228548 chr6:90439164 T/C cg13799429 chr6:90582589 CASP8AP2 -0.64 -5.95 -0.31 6.49e-9 Bipolar disorder; LIHC cis rs3820068 0.581 rs58425551 chr1:15922518 A/G cg17385448 chr1:15911702 AGMAT 0.35 6.15 0.32 2.21e-9 Systolic blood pressure; LIHC cis rs208520 1.000 rs12189683 chr6:66977716 A/C cg07460842 chr6:66804631 NA -0.67 -7.44 -0.37 7.95e-13 Exhaled nitric oxide output; LIHC cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.79 -0.34 4.92e-11 Gut microbiome composition (summer); LIHC cis rs2997447 0.761 rs61776596 chr1:26454968 T/C cg19633962 chr1:26362018 EXTL1 -0.65 -5.76 -0.3 1.87e-8 QRS complex (12-leadsum); LIHC cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs72781680 0.716 rs2712061 chr2:24026411 G/A cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.07e-9 Lymphocyte counts; LIHC cis rs9399135 1.000 rs9399135 chr6:135368314 G/A cg24558204 chr6:135376177 HBS1L 0.42 6.76 0.34 6.07e-11 Red blood cell count; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg06873352 chr17:61820015 STRADA 0.71 13.06 0.58 6.6e-32 Prudent dietary pattern; LIHC cis rs4555082 0.874 rs56263609 chr14:105756944 C/T cg10792982 chr14:105748885 BRF1 0.48 6.23 0.32 1.4e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs1712517 0.740 rs11191663 chr10:105118462 C/T cg05636881 chr10:105038444 INA 0.49 7.54 0.38 4.16e-13 Migraine; LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg05185784 chr16:90016020 DEF8 0.44 6.15 0.32 2.22e-9 Skin colour saturation; LIHC cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs7267979 1.000 rs2259928 chr20:25281834 G/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC trans rs3812049 0.737 rs790155 chr5:127498380 C/T cg16011800 chr17:1958478 HIC1 -0.46 -6.54 -0.33 2.29e-10 Lymphocyte counts;Red cell distribution width; LIHC cis rs2073499 0.872 rs41291724 chr3:50294066 C/G cg03645007 chr3:50255295 SLC38A3 0.56 6.56 0.33 1.99e-10 Schizophrenia; LIHC cis rs6840360 0.571 rs7692700 chr4:152552797 C/T cg22705602 chr4:152727874 NA -0.32 -6.21 -0.32 1.51e-9 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.676 rs1721999 chr11:49917372 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs34375054 0.526 rs883315 chr12:125676889 T/C cg25124228 chr12:125621409 AACS -0.45 -7.86 -0.39 5.1e-14 Post bronchodilator FEV1/FVC ratio; LIHC cis rs9948 1.000 rs13419073 chr2:97507554 G/C cg01990225 chr2:97406019 LMAN2L -0.59 -5.99 -0.31 5.19e-9 Erectile dysfunction and prostate cancer treatment; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01813165 chr2:202646406 ALS2 0.5 7.25 0.36 2.75e-12 Pancreatic cancer; LIHC cis rs7909074 0.966 rs879074 chr10:45400053 G/A cg05187965 chr10:45406764 TMEM72 -0.26 -6.45 -0.33 3.71e-10 Mean corpuscular volume; LIHC cis rs17270561 0.779 rs78589800 chr6:25883500 C/G cg16482183 chr6:26056742 HIST1H1C 0.63 7.65 0.38 2.09e-13 Iron status biomarkers; LIHC cis rs7618501 0.602 rs2526743 chr3:50115245 G/A cg24110177 chr3:50126178 RBM5 0.53 8.66 0.42 1.91e-16 Intelligence (multi-trait analysis); LIHC cis rs8014204 0.905 rs8014289 chr14:75377352 A/G cg08847533 chr14:75593920 NEK9 -0.39 -6.63 -0.34 1.29e-10 Caffeine consumption; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07283595 chr17:5372003 DHX33 0.51 7.11 0.36 6.76e-12 Lung function (FEV1/FVC); LIHC cis rs67311347 0.824 rs73073561 chr3:40357298 G/T cg00656387 chr3:40428638 ENTPD3 0.39 6.07 0.31 3.37e-9 Renal cell carcinoma; LIHC cis rs801193 0.527 rs2707837 chr7:66181073 G/C cg11764359 chr7:65958608 NA 0.76 12.99 0.57 1.2e-31 Aortic root size; LIHC cis rs4925386 0.921 rs11204472 chr20:60920887 G/A cg03945807 chr20:60948434 NA -0.36 -6.47 -0.33 3.37e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2292096 0.789 rs36041093 chr1:200696648 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.45 -6.03 -0.31 4.24e-9 Epilepsy; LIHC cis rs9486715 0.867 rs3849199 chr6:97049191 T/C cg06623918 chr6:96969491 KIAA0776 -0.86 -15.49 -0.64 2.2e-41 Headache; LIHC cis rs4889911 1.000 rs4889910 chr17:77839795 C/T cg21507958 chr17:78818871 RPTOR 0.4 5.8 0.3 1.53e-8 Electroencephalogram traits; LIHC cis rs1443512 0.812 rs4759058 chr12:54339052 C/A cg12374095 chr12:54320830 NA 0.39 5.76 0.3 1.83e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs1005277 0.579 rs2474568 chr10:38383147 A/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.4 -0.56 1.98e-29 Extrinsic epigenetic age acceleration; LIHC cis rs6088590 1.000 rs2295353 chr20:33356511 C/T cg06115741 chr20:33292138 TP53INP2 0.6 8.24 0.41 3.81e-15 Coronary artery disease; LIHC cis rs10752881 1.000 rs10797808 chr1:182979623 T/C ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs10504229 0.679 rs4738574 chr8:58033771 T/C cg20607798 chr8:58055168 NA 0.46 6.71 0.34 7.96e-11 Developmental language disorder (linguistic errors); LIHC cis rs3809566 0.637 rs8026047 chr15:63323347 C/G cg12160578 chr15:63334699 TPM1 0.63 8.97 0.44 1.97e-17 Platelet count; LIHC cis rs4975616 0.804 rs457130 chr5:1336178 A/T cg06550200 chr5:1325588 CLPTM1L -0.64 -10.05 -0.48 5.35e-21 Lung cancer; LIHC cis rs11608355 0.515 rs2270361 chr12:109935894 G/C cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs78456975 1.000 rs10205916 chr2:1558451 A/T cg01028140 chr2:1542097 TPO 0.56 6.69 0.34 8.98e-11 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg09455208 chr3:40491958 NA 0.39 7.8 0.39 7.39e-14 Renal cell carcinoma; LIHC cis rs7582720 1.000 rs72926794 chr2:203827432 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs7618501 0.633 rs3774733 chr3:50037123 C/G cg21659725 chr3:3221576 CRBN 0.69 11.3 0.52 2.25e-25 Intelligence (multi-trait analysis); LIHC trans rs412658 0.704 rs8105767 chr19:22215441 A/G cg17074339 chr11:11642133 GALNTL4 -0.42 -6.16 -0.32 2.08e-9 Telomere length; LIHC cis rs2153535 0.601 rs2143352 chr6:8530248 G/C cg23788917 chr6:8435910 SLC35B3 0.64 9.08 0.44 8.77e-18 Motion sickness; LIHC cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg15691649 chr6:25882328 NA 0.78 11.0 0.51 2.6e-24 Blood metabolite levels; LIHC cis rs882732 1.000 rs5510 chr14:95033356 A/G cg14866387 chr14:95027382 SERPINA4 0.46 6.96 0.35 1.72e-11 Blood protein levels; LIHC cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg19774624 chr17:42201019 HDAC5 0.57 8.53 0.42 4.94e-16 Total body bone mineral density; LIHC cis rs116248771 0.739 rs12633687 chr3:158338168 G/T cg16708174 chr3:158430962 RARRES1 0.47 6.18 0.32 1.8e-9 diarrhoeal disease at age 2; LIHC cis rs34779708 0.931 rs12773169 chr10:35366462 G/C cg04310649 chr10:35416472 CREM -0.42 -5.78 -0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9303401 0.659 rs2072316 chr17:56604813 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.89 11.64 0.53 1.27e-26 Cognitive test performance; LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs7520050 0.966 rs10890361 chr1:46346234 A/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.42 5.99 0.31 5.24e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6089584 0.927 rs3787427 chr20:60579789 T/C cg13770153 chr20:60521292 NA -0.33 -6.42 -0.33 4.47e-10 Body mass index; LIHC cis rs6938 0.534 rs1127796 chr15:75193004 C/T cg14664628 chr15:75095509 CSK 0.49 6.34 0.32 7.47e-10 Breast cancer; LIHC cis rs74233809 1.000 rs3740390 chr10:104638480 C/T cg03493300 chr10:104813866 CNNM2 0.46 6.08 0.31 3.27e-9 Birth weight; LIHC cis rs4319547 0.695 rs113841747 chr12:122886088 G/T cg05707623 chr12:122985044 ZCCHC8 0.56 7.38 0.37 1.21e-12 Body mass index; LIHC cis rs2645694 0.533 rs2703125 chr4:77819900 T/C cg06046430 chr4:77819534 ANKRD56 0.48 6.41 0.33 4.97e-10 Emphysema distribution in smoking; LIHC cis rs7072216 0.763 rs6584202 chr10:100170383 G/A cg26618903 chr10:100175079 PYROXD2 -0.39 -6.24 -0.32 1.26e-9 Metabolite levels; LIHC cis rs12586317 0.620 rs17091786 chr14:35565856 A/T cg05294307 chr14:35346193 BAZ1A -0.46 -6.75 -0.34 6.37e-11 Psoriasis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03952484 chr1:149899818 SF3B4 0.36 6.05 0.31 3.7e-9 Cognitive function; LIHC cis rs9303401 0.614 rs35308719 chr17:57163501 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.45 0.56 1.34e-29 Cognitive test performance; LIHC cis rs35110281 0.782 rs4818856 chr21:45043495 A/G cg01579765 chr21:45077557 HSF2BP -0.35 -6.58 -0.34 1.72e-10 Mean corpuscular volume; LIHC cis rs9811920 0.609 rs809415 chr3:99582242 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.89 0.35 2.75e-11 Axial length; LIHC cis rs11190604 0.731 rs10883480 chr10:102163821 G/T cg07080220 chr10:102295463 HIF1AN -0.44 -6.26 -0.32 1.18e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs600806 0.627 rs2359652 chr1:110008720 T/A cg10127483 chr1:110009974 SYPL2 0.48 6.06 0.31 3.53e-9 Intelligence (multi-trait analysis); LIHC cis rs7089973 0.604 rs7915943 chr10:116618077 G/A cg23260525 chr10:116636907 FAM160B1 0.39 7.63 0.38 2.41e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs7208859 0.623 rs35916850 chr17:29011173 G/A cg13385521 chr17:29058706 SUZ12P 0.67 6.4 0.33 5.05e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs8062405 0.690 rs62034351 chr16:28565489 G/A cg16576597 chr16:28551801 NUPR1 0.48 7.34 0.37 1.53e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1552244 0.882 rs67895180 chr3:10026079 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs12477438 0.834 rs1563107 chr2:99701276 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.58 8.29 0.41 2.56e-15 Chronic sinus infection; LIHC cis rs2816062 0.735 rs2816054 chr1:18896431 C/T cg18795169 chr1:18902165 NA -0.81 -18.3 -0.7 1.2e-52 Urate levels in lean individuals; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.14 0.55 1.86e-28 Prudent dietary pattern; LIHC cis rs8062405 0.690 rs6498089 chr16:28629300 C/T cg00204512 chr16:28754710 NA -0.38 -6.29 -0.32 9.96e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2075371 1.000 rs2598296 chr7:133992985 C/T cg11752832 chr7:134001865 SLC35B4 0.52 7.66 0.38 1.92e-13 Mean platelet volume; LIHC cis rs13191362 1.000 rs13204439 chr6:163015358 A/C cg21926612 chr6:163149169 PACRG;PARK2 -0.6 -5.85 -0.3 1.17e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8072100 0.840 rs11079774 chr17:45479706 C/G cg08085267 chr17:45401833 C17orf57 -0.55 -8.24 -0.41 3.6e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs208520 0.690 rs12197578 chr6:66725905 C/T cg07460842 chr6:66804631 NA 0.78 9.03 0.44 1.31e-17 Exhaled nitric oxide output; LIHC cis rs7116495 0.881 rs6592451 chr11:71674937 G/A cg26138937 chr11:71823887 C11orf51 -0.82 -8.17 -0.4 6.02e-15 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg02290350 chr8:58132656 NA 0.45 8.41 0.41 1.1e-15 Developmental language disorder (linguistic errors); LIHC cis rs295140 0.526 rs295113 chr2:201197816 C/G cg23649088 chr2:200775458 C2orf69 0.43 5.95 0.31 6.46e-9 QT interval; LIHC cis rs941873 0.868 rs2233718 chr10:81108956 A/G cg09469691 chr10:81107165 PPIF 0.69 10.54 0.5 1.14e-22 Height; LIHC cis rs9534288 0.659 rs9534314 chr13:46654844 A/G cg15192986 chr13:46630673 CPB2 -0.45 -6.45 -0.33 3.8e-10 Blood protein levels; LIHC cis rs5758659 0.737 rs10854749 chr22:42447341 G/T cg19513890 chr22:42538836 CYP2D7P1 -0.41 -7.85 -0.39 5.51e-14 Cognitive function; LIHC cis rs708547 0.647 rs1718839 chr4:57827206 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.47 7.02 0.35 1.21e-11 Response to bleomycin (chromatid breaks); LIHC trans rs916888 0.821 rs70600 chr17:44860021 C/T cg26692224 chr17:62915920 LRRC37A3 -0.71 -6.78 -0.34 5.14e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2797160 1.000 rs2747722 chr6:126009629 A/G cg05901451 chr6:126070800 HEY2 0.45 7.44 0.37 8.16e-13 Endometrial cancer; LIHC cis rs2050392 0.630 rs303427 chr10:30739780 G/A cg25182066 chr10:30743637 MAP3K8 -0.54 -8.27 -0.41 3.1e-15 Inflammatory bowel disease; LIHC cis rs9522267 0.737 rs9522285 chr13:112230701 C/T cg10483660 chr13:112241077 NA -0.23 -5.84 -0.3 1.2e-8 Hepatitis; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg02447779 chr16:31505062 C16orf58 -0.39 -6.19 -0.32 1.75e-9 Bipolar disorder; LIHC cis rs5753618 0.561 rs5753543 chr22:31685458 G/A cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.45e-10 Colorectal cancer; LIHC cis rs2836950 0.545 rs2836940 chr21:40588696 T/C cg11890956 chr21:40555474 PSMG1 -0.47 -7.77 -0.39 9.16e-14 Menarche (age at onset); LIHC cis rs2153535 0.580 rs5001130 chr6:8442298 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.51 0.53 3.97e-26 Motion sickness; LIHC cis rs68170813 0.599 rs11769901 chr7:106958505 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.12e-9 Coronary artery disease; LIHC trans rs12780046 0.656 rs7085445 chr10:100858581 C/T cg05980083 chr9:112191166 PTPN3 -0.46 -6.09 -0.31 2.95e-9 Non-glioblastoma glioma; LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg18306943 chr3:40428807 ENTPD3 0.42 7.37 0.37 1.3e-12 Renal cell carcinoma; LIHC cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg06481639 chr22:41940642 POLR3H -0.69 -7.07 -0.36 8.51e-12 Vitiligo; LIHC cis rs9325144 0.510 rs7952795 chr12:38720686 C/T cg26384229 chr12:38710491 ALG10B 0.56 7.79 0.39 8.17e-14 Morning vs. evening chronotype; LIHC cis rs4713118 0.513 rs149972 chr6:27983227 C/T cg16479474 chr6:28041457 NA 0.38 6.29 0.32 9.81e-10 Parkinson's disease; LIHC cis rs35110281 0.782 rs9981291 chr21:45031458 A/G cg01579765 chr21:45077557 HSF2BP -0.35 -6.58 -0.34 1.72e-10 Mean corpuscular volume; LIHC cis rs8060686 0.565 rs11555011 chr16:68088485 A/G cg09835421 chr16:68378352 PRMT7 -0.49 -5.77 -0.3 1.8e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs2832191 0.720 rs2832200 chr21:30499165 G/A cg24692254 chr21:30365293 RNF160 -0.59 -10.28 -0.49 8.89e-22 Dental caries; LIHC cis rs7208859 0.623 rs8068645 chr17:29104342 T/A cg14067834 chr17:29058358 SUZ12P 0.71 7.01 0.35 1.26e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs826838 0.510 rs17523988 chr12:39222785 A/C cg26384229 chr12:38710491 ALG10B 0.72 8.74 0.43 1.04e-16 Heart rate; LIHC cis rs853679 0.517 rs9393897 chr6:28127710 G/T cg16479474 chr6:28041457 NA 0.46 6.46 0.33 3.5e-10 Depression; LIHC cis rs10845606 1.000 rs10845607 chr12:12835228 C/T cg04607235 chr12:12878440 APOLD1 -0.74 -9.55 -0.46 2.67e-19 Systemic lupus erythematosus; LIHC cis rs9322817 0.691 rs4460239 chr6:105325562 C/T cg02098413 chr6:105308735 HACE1 0.41 7.59 0.38 3.02e-13 Thyroid stimulating hormone; LIHC cis rs9733 0.818 rs7520022 chr1:150659173 C/G cg13175981 chr1:150552382 MCL1 0.51 8.03 0.4 1.54e-14 Tonsillectomy; LIHC cis rs992157 1.000 rs736730 chr2:219120255 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.88 0.57 3.23e-31 Colorectal cancer; LIHC cis rs1577917 1.000 rs1911552 chr6:86638024 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.81 -0.39 7.29e-14 Response to antipsychotic treatment; LIHC cis rs4474465 1.000 rs10899518 chr11:78180508 A/C cg02023728 chr11:77925099 USP35 0.33 5.89 0.3 9.28e-9 Alzheimer's disease (survival time); LIHC cis rs12478296 0.901 rs7423119 chr2:243005488 T/A cg06360820 chr2:242988706 NA -0.81 -12.36 -0.56 3.02e-29 Obesity-related traits; LIHC cis rs910316 1.000 rs2098297 chr14:75619118 G/T cg11812906 chr14:75593930 NEK9 -0.73 -14.52 -0.62 1.47e-37 Height; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg17271960 chr1:1550779 MIB2 0.52 6.26 0.32 1.17e-9 Hepatitis; LIHC cis rs896854 0.812 rs4582532 chr8:95969257 G/A cg13393036 chr8:95962371 TP53INP1 -0.37 -8.54 -0.42 4.32e-16 Type 2 diabetes; LIHC cis rs10751667 0.600 rs14346 chr11:1011829 T/C cg10932868 chr11:921992 NA 0.31 5.8 0.3 1.52e-8 Alzheimer's disease (late onset); LIHC cis rs9309473 0.607 rs1522926 chr2:73591241 T/C cg20560298 chr2:73613845 ALMS1 -0.46 -7.37 -0.37 1.27e-12 Metabolite levels; LIHC cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg26818010 chr10:134567672 INPP5A -0.71 -8.81 -0.43 6.37e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1198430 0.925 rs2510072 chr1:23769674 A/G cg19827787 chr1:23763612 ASAP3 0.35 6.02 0.31 4.39e-9 Total cholesterol levels; LIHC cis rs4891159 0.584 rs690397 chr18:74117767 C/T cg24786174 chr18:74118243 ZNF516 0.85 17.39 0.68 5.72e-49 Longevity; LIHC cis rs72653721 0.730 rs12664138 chr6:11039799 T/C cg13562911 chr6:11044106 ELOVL2 0.53 7.59 0.38 3.16e-13 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs9902453 0.866 rs4795529 chr17:28443549 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 10.74 0.5 2.26e-23 Coffee consumption (cups per day); LIHC cis rs9549367 0.713 rs9549681 chr13:113829873 T/C cg18105134 chr13:113819100 PROZ -0.76 -13.02 -0.58 9.81e-32 Platelet distribution width; LIHC cis rs1577917 0.655 rs9342045 chr6:86425148 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.05 0.44 1.08e-17 Response to antipsychotic treatment; LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg10755058 chr3:40428713 ENTPD3 -0.42 -7.03 -0.36 1.12e-11 Renal cell carcinoma; LIHC cis rs2153535 0.541 rs5026687 chr6:8473957 A/T cg21535247 chr6:8435926 SLC35B3 0.61 8.03 0.4 1.59e-14 Motion sickness; LIHC cis rs2274273 0.967 rs2094102 chr14:55591098 T/C cg04306507 chr14:55594613 LGALS3 0.33 6.14 0.32 2.24e-9 Protein biomarker; LIHC cis rs2933343 0.679 rs789221 chr3:128591625 A/G cg24203234 chr3:128598194 ACAD9 0.45 6.22 0.32 1.47e-9 IgG glycosylation; LIHC trans rs2727020 0.619 rs1829979 chr11:49436875 T/G cg15704280 chr7:45808275 SEPT13 -0.76 -11.3 -0.52 2.34e-25 Coronary artery disease; LIHC cis rs6964587 0.967 rs6980247 chr7:91594228 T/A cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs2153535 0.580 rs7763190 chr6:8484197 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs35110281 0.811 rs7275705 chr21:45056453 G/C cg21573476 chr21:45109991 RRP1B -0.57 -10.83 -0.51 1.11e-23 Mean corpuscular volume; LIHC cis rs1843834 0.505 rs2140508 chr2:225355839 G/T cg12698349 chr2:225449008 CUL3 0.69 10.76 0.5 1.95e-23 IgE levels in asthmatics (D.p. specific); LIHC trans rs208520 0.837 rs208509 chr6:66941706 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -7.96 -0.4 2.5e-14 Exhaled nitric oxide output; LIHC cis rs10779751 1.000 rs10779751 chr1:11284336 A/G cg08854313 chr1:11322531 MTOR 0.81 11.39 0.52 1.08e-25 Body mass index; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs61712019 1.000 rs61712019 chr2:77704889 C/T cg11252801 chr2:77748917 LRRTM4 0.51 7.77 0.39 9.52e-14 Schizophrenia; LIHC cis rs11785693 0.862 rs11778367 chr8:4988398 T/C cg26367366 chr8:4980734 NA 0.59 6.34 0.32 7.22e-10 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.68 0.46 9.54e-20 Platelet count; LIHC cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg26939375 chr7:64535504 NA 0.48 7.22 0.36 3.46e-12 Aortic root size; LIHC cis rs600806 0.821 rs3879451 chr1:109909269 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs3770081 1.000 rs77621359 chr2:86330353 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.88 -9.26 -0.45 2.39e-18 Facial emotion recognition (sad faces); LIHC cis rs1801251 0.711 rs778339 chr2:233739678 T/C cg08000102 chr2:233561755 GIGYF2 -0.71 -10.68 -0.5 3.74e-23 Coronary artery disease; LIHC cis rs6762477 0.748 rs11717349 chr3:50223977 C/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.51 -7.8 -0.39 7.62e-14 Menarche (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg24141198 chr1:115259970 CSDE1;NRAS 0.47 6.79 0.34 5.08e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs17685 0.884 rs3823882 chr7:75631913 T/C cg19862616 chr7:65841803 NCRNA00174 -0.73 -12.81 -0.57 5.85e-31 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9399135 0.660 rs4472368 chr6:135274232 A/G cg24558204 chr6:135376177 HBS1L 0.4 6.48 0.33 3.25e-10 Red blood cell count; LIHC cis rs250677 0.958 rs36070 chr5:148417240 T/C cg18129178 chr5:148520854 ABLIM3 -0.48 -6.49 -0.33 3.1e-10 Breast cancer; LIHC cis rs875971 0.666 rs13242072 chr7:65765988 A/G cg11764359 chr7:65958608 NA -0.64 -8.82 -0.43 6.16e-17 Aortic root size; LIHC cis rs9503598 0.714 rs7758776 chr6:3452245 C/T cg00476032 chr6:3446245 SLC22A23 0.44 8.88 0.43 3.74e-17 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.56e-13 Prudent dietary pattern; LIHC cis rs2289583 0.642 rs8034281 chr15:75384227 A/G cg15902774 chr15:75289873 SCAMP5 -0.33 -6.0 -0.31 5e-9 Systemic lupus erythematosus; LIHC cis rs6089584 0.508 rs6061988 chr20:60626300 C/T cg06108461 chr20:60628389 TAF4 -0.65 -9.0 -0.44 1.58e-17 Body mass index; LIHC cis rs7408868 0.831 rs1548555 chr19:15278057 A/G cg14696996 chr19:15285081 NOTCH3 0.55 7.3 0.37 2.02e-12 Pulse pressure; LIHC trans rs3780486 0.846 rs4584234 chr9:33147479 G/A cg04842962 chr6:43655489 MRPS18A 0.97 19.98 0.73 2.12e-59 IgG glycosylation; LIHC cis rs10857712 0.703 rs12253520 chr10:135235321 C/A cg01444801 chr10:135216882 MTG1 -0.63 -9.32 -0.45 1.5e-18 Systemic lupus erythematosus; LIHC cis rs523522 0.962 rs670568 chr12:121021206 C/T cg27279351 chr12:120934652 DYNLL1 0.68 11.96 0.54 8.87e-28 High light scatter reticulocyte count; LIHC cis rs9503598 0.502 rs6937621 chr6:3430128 G/A cg00476032 chr6:3446245 SLC22A23 -0.32 -5.84 -0.3 1.2e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs8067354 0.645 rs2645486 chr17:57885901 T/A cg02344993 chr17:57696989 CLTC 0.72 12.37 0.56 2.76e-29 Hemoglobin concentration; LIHC cis rs9640161 0.659 rs7806429 chr7:150013393 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.44 -7.84 -0.39 5.82e-14 Blood protein levels;Circulating chemerin levels; LIHC trans rs7677751 0.806 rs73252942 chr4:55104604 T/C cg17183009 chr3:120277827 NA 0.52 6.23 0.32 1.38e-9 Corneal astigmatism; LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg02782426 chr3:40428986 ENTPD3 -0.32 -6.06 -0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs600806 0.850 rs3768494 chr1:109935427 A/G cg23091122 chr1:110024289 SYPL2 -0.45 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC trans rs11722228 0.549 rs2241488 chr4:10101131 T/C cg26043149 chr18:55253948 FECH 0.98 13.79 0.6 1.1e-34 Gout;Urate levels;Serum uric acid levels; LIHC cis rs9513627 1.000 rs73556172 chr13:100121684 A/G cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs5769765 0.908 rs9616217 chr22:50318946 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.74 -9.27 -0.45 2.1e-18 Schizophrenia; LIHC cis rs10911251 0.528 rs10911248 chr1:183080564 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.53 0.49 1.24e-22 Colorectal cancer; LIHC cis rs4561483 0.767 rs33633 chr16:11994857 A/C cg08843971 chr16:11963173 GSPT1 -0.43 -8.51 -0.42 5.4e-16 Testicular germ cell tumor; LIHC cis rs10870270 1.000 rs11146338 chr10:133770291 C/G cg08754478 chr10:133766260 PPP2R2D -0.54 -8.03 -0.4 1.58e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2070488 0.965 rs3749386 chr3:38496065 C/T cg24069376 chr3:38537580 EXOG 0.43 8.04 0.4 1.48e-14 Electrocardiographic conduction measures; LIHC cis rs9814567 1.000 rs2370578 chr3:134199612 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.73 -0.3 2.2e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs477895 0.652 rs72920332 chr11:63947071 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.56 0.46 2.37e-19 Mean platelet volume; LIHC cis rs17106184 0.892 rs72900926 chr1:51101616 C/G cg07174182 chr1:51127561 FAF1 -0.65 -7.04 -0.36 1.03e-11 Type 2 diabetes; LIHC cis rs4629710 0.592 rs3777476 chr6:131533821 A/C cg12606694 chr6:131520996 AKAP7 0.58 6.75 0.34 6.29e-11 Multiple myeloma (IgH translocation); LIHC trans rs877282 0.898 rs34490091 chr10:765800 A/C cg22713356 chr15:30763199 NA 1.39 11.65 0.53 1.2e-26 Uric acid levels; LIHC trans rs877282 0.898 rs12358513 chr10:757571 A/G cg22713356 chr15:30763199 NA 1.42 12.22 0.55 9.43e-29 Uric acid levels; LIHC cis rs7312933 1.000 rs10880230 chr12:42450253 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.48 6.79 0.34 4.88e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs76419734 0.510 rs4699198 chr4:106645771 G/A cg24545054 chr4:106630052 GSTCD;INTS12 0.77 9.0 0.44 1.64e-17 Post bronchodilator FEV1; LIHC cis rs6782228 0.606 rs4857919 chr3:128407495 C/T cg16766828 chr3:128327626 NA -0.38 -6.07 -0.31 3.46e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs6121246 0.657 rs74392247 chr20:30241737 C/T cg13852791 chr20:30311386 BCL2L1 0.76 6.25 0.32 1.21e-9 Mean corpuscular hemoglobin; LIHC cis rs7619427 0.643 rs6800613 chr3:44098325 T/C cg24966902 chr3:44043705 NA 0.51 6.75 0.34 6.47e-11 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04073608 chr11:65268100 MALAT1 -0.51 -6.38 -0.33 5.63e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12142240 0.698 rs72890727 chr1:46860237 G/A cg00530320 chr1:46809349 NSUN4 0.53 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC trans rs875971 0.522 rs1968127 chr7:66056803 C/T cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.77e-11 Aortic root size; LIHC cis rs9814567 1.000 rs6766818 chr3:134226159 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.25 -0.55 7.24e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08980237 chr3:156534860 NA -0.48 -6.17 -0.32 1.96e-9 Systolic blood pressure; LIHC cis rs4665809 0.525 rs10865402 chr2:26535383 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.64 -8.94 -0.44 2.56e-17 Gut microbiome composition (summer); LIHC trans rs1814175 0.740 rs10839439 chr11:49918240 C/T cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs12477438 0.834 rs1563106 chr2:99701381 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.58 -8.24 -0.41 3.78e-15 Chronic sinus infection; LIHC cis rs2576037 0.526 rs8095373 chr18:44527895 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.13 -0.36 5.99e-12 Personality dimensions; LIHC cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg06212747 chr3:49208901 KLHDC8B -0.65 -9.01 -0.44 1.47e-17 Menarche (age at onset); LIHC cis rs12497850 0.931 rs11924597 chr3:48937790 T/C cg07636037 chr3:49044803 WDR6 0.93 16.95 0.68 3.21e-47 Parkinson's disease; LIHC cis rs2380220 0.808 rs2613547 chr6:95910311 C/T cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg24503407 chr1:205819492 PM20D1 -0.68 -9.61 -0.46 1.7e-19 Menarche (age at onset); LIHC cis rs9814567 1.000 rs1880376 chr3:134270347 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs668210 0.793 rs506873 chr11:65767215 A/C cg17712092 chr4:129076599 LARP1B -0.58 -6.2 -0.32 1.67e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9517320 0.967 rs9517337 chr13:99181647 A/C cg07423050 chr13:99094983 FARP1 0.36 5.92 0.31 7.65e-9 Longevity; LIHC cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC cis rs8073060 0.586 rs225291 chr17:33927126 A/G cg20932281 chr17:33905541 PEX12 -0.53 -6.14 -0.32 2.29e-9 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2072499 1.000 rs2241108 chr1:156181007 C/G cg25208724 chr1:156163844 SLC25A44 0.92 15.86 0.65 7.73e-43 Testicular germ cell tumor; LIHC cis rs9633740 1.000 rs10748526 chr10:82273079 T/C cg01528321 chr10:82214614 TSPAN14 0.59 8.22 0.41 4.19e-15 Post bronchodilator FEV1; LIHC cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg21171335 chr12:122356390 WDR66 0.47 7.76 0.39 9.78e-14 Mean corpuscular volume; LIHC cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg03264133 chr6:25882463 NA 0.62 8.89 0.43 3.61e-17 Blood metabolite levels; LIHC cis rs9467773 0.525 rs1535274 chr6:26520747 A/C cg11502198 chr6:26597334 ABT1 0.6 7.98 0.4 2.23e-14 Intelligence (multi-trait analysis); LIHC cis rs7666738 0.830 rs11942114 chr4:99066261 C/G cg05340658 chr4:99064831 C4orf37 0.71 13.02 0.58 9.36e-32 Colonoscopy-negative controls vs population controls; LIHC trans rs6058796 0.892 rs6141780 chr20:31262423 C/G cg02600331 chr11:130417168 NA -0.36 -7.85 -0.39 5.51e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs61008539 0.586 rs6959154 chr7:856320 C/T cg04727924 chr7:799746 HEATR2 0.46 6.81 0.35 4.35e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs6089829 0.962 rs11086151 chr20:61664644 C/T cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs10197940 0.624 rs10497081 chr2:152353395 T/G cg06191203 chr2:152266755 RIF1 -0.44 -7.5 -0.38 5.51e-13 Lung cancer; LIHC cis rs59698941 0.943 rs56927472 chr5:132226038 T/A cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18030105 chr11:3396237 ZNF195 -0.46 -6.92 -0.35 2.21e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs3796352 1.000 rs11718834 chr3:52963668 A/C cg07884673 chr3:53033167 SFMBT1 0.87 6.48 0.33 3.28e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs12042938 0.507 rs1765776 chr1:231731607 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.59 -7.88 -0.39 4.3e-14 Neuranatomic and neurocognitive phenotypes; LIHC cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg10862848 chr6:42927986 GNMT -0.26 -6.22 -0.32 1.45e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg02290350 chr8:58132656 NA 0.51 10.88 0.51 7.37e-24 Developmental language disorder (linguistic errors); LIHC cis rs10174077 0.687 rs10172023 chr2:152476028 C/G cg06191203 chr2:152266755 RIF1 -0.42 -7.05 -0.36 9.65e-12 Squamous cell lung carcinoma; LIHC cis rs733592 0.507 rs7304428 chr12:48494275 T/G cg21466736 chr12:48725269 NA 0.33 5.92 0.3 7.87e-9 Plateletcrit; LIHC cis rs1799949 0.965 rs8071278 chr17:41193910 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.85 0.3 1.12e-8 Menopause (age at onset); LIHC cis rs1113500 0.814 rs12039712 chr1:108641199 A/G cg06207961 chr1:108661230 NA 0.32 6.07 0.31 3.38e-9 Growth-regulated protein alpha levels; LIHC cis rs172166 0.694 rs2791332 chr6:28108788 C/T cg16479474 chr6:28041457 NA 0.37 6.18 0.32 1.78e-9 Cardiac Troponin-T levels; LIHC cis rs17253792 0.822 rs76201070 chr14:56063604 A/C cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg00684032 chr4:1343700 KIAA1530 0.52 7.58 0.38 3.3e-13 Obesity-related traits; LIHC cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg17554472 chr22:41940697 POLR3H 0.54 5.9 0.3 8.82e-9 Vitiligo; LIHC cis rs921968 0.565 rs6723334 chr2:219629303 C/T cg02985541 chr2:219472218 PLCD4 0.37 6.51 0.33 2.75e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -14.28 -0.61 1.32e-36 Alzheimer's disease; LIHC cis rs6445975 0.715 rs6769100 chr3:58259999 C/T cg23715586 chr3:58305044 RPP14 0.34 5.82 0.3 1.39e-8 Systemic lupus erythematosus; LIHC cis rs1982963 1.000 rs3742536 chr14:52507429 C/T cg10843707 chr14:52510701 NID2 0.45 8.26 0.41 3.27e-15 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6547741 1.000 rs4666007 chr2:27856495 T/C cg27432699 chr2:27873401 GPN1 0.77 12.92 0.57 2.32e-31 Oral cavity cancer; LIHC cis rs9902453 0.904 rs7212292 chr17:28409264 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.61 -0.59 5.31e-34 Coffee consumption (cups per day); LIHC cis rs270601 0.710 rs4705852 chr5:131602807 A/G cg24060327 chr5:131705240 SLC22A5 -0.53 -6.94 -0.35 1.96e-11 Acylcarnitine levels; LIHC cis rs7520050 0.966 rs34102169 chr1:46424864 G/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 5.93 0.31 7.52e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6840360 1.000 rs751012 chr4:152602247 A/C cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.42e-10 Intelligence (multi-trait analysis); LIHC cis rs288342 0.832 rs288303 chr2:183655230 G/T cg02625481 chr2:183667124 NA -0.29 -5.96 -0.31 6.25e-9 Recurrent major depressive disorder; LIHC cis rs2153535 0.580 rs915352 chr6:8442766 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs6964587 0.967 rs7786031 chr7:91649001 T/G cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC cis rs11382616 1 rs11382616 chr14:103081465 G/GC cg12046867 chr14:103022105 NA -0.38 -5.79 -0.3 1.59e-8 Plateletcrit;Platelet count; LIHC cis rs798554 0.634 rs6970963 chr7:2821271 C/T cg19717773 chr7:2847554 GNA12 -0.41 -7.31 -0.37 1.88e-12 Height; LIHC cis rs6754311 0.731 rs6719488 chr2:136575199 G/T cg25344623 chr2:136566232 LCT 0.42 8.59 0.42 3.11e-16 Mosquito bite size; LIHC cis rs344364 0.511 rs12599337 chr16:1946751 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 0.52 7.15 0.36 5.24e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs6582630 0.593 rs7134006 chr12:38596245 A/C cg13010199 chr12:38710504 ALG10B 0.53 6.31 0.32 8.67e-10 Drug-induced liver injury (flucloxacillin); LIHC cis rs3106136 0.814 rs6532482 chr4:95277414 C/T cg11021082 chr4:95130006 SMARCAD1 -0.37 -6.41 -0.33 4.73e-10 Capecitabine sensitivity; LIHC cis rs858239 0.601 rs1981665 chr7:23167969 T/C cg23682824 chr7:23144976 KLHL7 0.45 6.68 0.34 9.63e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs9916302 0.861 rs3889368 chr17:37683231 C/T cg03013999 chr17:37608204 MED1 0.35 5.75 0.3 1.94e-8 Glomerular filtration rate (creatinine); LIHC cis rs1568889 1.000 rs10767693 chr11:28093926 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.65 13.28 0.58 9.25e-33 Bipolar disorder; LIHC cis rs933688 0.526 rs7727632 chr5:90609009 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 -0.42 -5.93 -0.31 7.25e-9 Smoking behavior; LIHC cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg05368731 chr17:41323189 NBR1 0.7 11.55 0.53 2.72e-26 Menopause (age at onset); LIHC cis rs4819052 0.851 rs2838833 chr21:46665160 C/T cg22633049 chr21:46681294 NA -0.36 -6.11 -0.31 2.65e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2932538 0.922 rs999923 chr1:113110548 T/C cg22162597 chr1:113214053 CAPZA1 0.73 11.03 0.51 2.09e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs66887589 0.616 rs6822808 chr4:120217365 C/A cg09307838 chr4:120376055 NA 0.54 7.88 0.39 4.5e-14 Diastolic blood pressure; LIHC cis rs10845606 1.000 rs10845606 chr12:12834894 G/T cg09462578 chr12:12878428 APOLD1 -0.74 -10.02 -0.48 6.64e-21 Systemic lupus erythematosus; LIHC cis rs77633900 0.772 rs494268 chr15:76815713 T/C cg21673338 chr15:77095150 SCAPER -0.53 -5.92 -0.3 7.98e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs7772486 0.875 rs13204280 chr6:146415368 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.97 0.31 5.94e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7772486 0.688 rs1884364 chr6:146337817 C/G cg23711669 chr6:146136114 FBXO30 0.58 8.84 0.43 5.22e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs11971779 0.680 rs6962186 chr7:139034806 T/C cg07862535 chr7:139043722 LUC7L2 0.58 10.12 0.48 3.07e-21 Diisocyanate-induced asthma; LIHC cis rs17106184 0.892 rs72900998 chr1:51205760 T/C cg07174182 chr1:51127561 FAF1 -0.63 -6.85 -0.35 3.47e-11 Type 2 diabetes; LIHC cis rs9560113 1.000 rs9555809 chr13:112181401 T/C cg14154082 chr13:112174009 NA 0.3 6.26 0.32 1.16e-9 Menarche (age at onset); LIHC cis rs644799 1.000 rs2508289 chr11:95624669 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 15.75 0.65 2e-42 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs651907 0.557 rs11917682 chr3:101355427 G/A cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.11 -0.31 2.64e-9 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25262866 chr7:16686311 BZW2;ANKMY2 0.41 6.35 0.32 6.69e-10 Cognitive function; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg22903471 chr2:27725779 GCKR -0.52 -9.03 -0.44 1.29e-17 Total body bone mineral density; LIHC cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg24549020 chr5:56110836 MAP3K1 0.51 6.63 0.34 1.3100000000000001e-10 Initial pursuit acceleration; LIHC cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -14.0 -0.6 1.66e-35 Alzheimer's disease; LIHC cis rs1799949 0.965 rs9911630 chr17:41188342 A/G cg05368731 chr17:41323189 NBR1 0.69 11.62 0.53 1.5e-26 Menopause (age at onset); LIHC cis rs826838 1.000 rs55828987 chr12:39056421 A/C cg13010199 chr12:38710504 ALG10B 0.53 6.5 0.33 2.79e-10 Heart rate; LIHC cis rs35306767 0.668 rs12356612 chr10:1055055 C/T cg26597838 chr10:835615 NA 0.84 8.3 0.41 2.5e-15 Eosinophil percentage of granulocytes; LIHC cis rs7843479 0.601 rs7220 chr8:21863290 G/A cg17168535 chr8:21777572 XPO7 0.56 10.01 0.48 7.54e-21 Mean corpuscular volume; LIHC cis rs798554 0.797 rs2107964 chr7:2863574 G/A cg04166393 chr7:2884313 GNA12 0.5 6.57 0.33 1.91e-10 Height; LIHC cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg02034447 chr16:89574710 SPG7 0.45 6.81 0.35 4.5e-11 Multiple myeloma (IgH translocation); LIHC trans rs61931739 0.500 rs11053207 chr12:34459827 A/G cg26384229 chr12:38710491 ALG10B 0.64 8.15 0.4 6.95e-15 Morning vs. evening chronotype; LIHC trans rs2727020 0.553 rs61904166 chr11:49581461 T/C cg15704280 chr7:45808275 SEPT13 -0.98 -20.5 -0.74 1.72e-61 Coronary artery disease; LIHC cis rs1865760 1.000 rs7739966 chr6:25906040 T/C cg17691542 chr6:26056736 HIST1H1C 0.41 6.09 0.31 3.04e-9 Height; LIHC cis rs344364 0.511 rs1742473 chr16:1953095 T/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.39 -0.37 1.14e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs3806933 0.500 rs10491423 chr5:110453977 C/A cg04022379 chr5:110408740 TSLP 0.57 9.16 0.44 4.83e-18 Eosinophilic esophagitis; LIHC trans rs41997 1.000 rs41997 chr7:117991895 A/G cg09887251 chr4:1024735 NA -0.34 -6.05 -0.31 3.72e-9 Response to platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs35110281 0.626 rs162367 chr21:44934857 A/G cg04455712 chr21:45112962 RRP1B 0.41 6.96 0.35 1.76e-11 Mean corpuscular volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21584983 chr19:11640070 ECSIT 0.46 6.76 0.34 6.09e-11 Pancreatic cancer; LIHC cis rs2404602 0.692 rs3110382 chr15:77148688 G/A cg03037974 chr15:76606532 NA -0.71 -13.88 -0.6 4.72e-35 Blood metabolite levels; LIHC trans rs2235573 0.527 rs139879 chr22:38364552 T/C cg19894588 chr14:64061835 NA 0.47 6.15 0.32 2.22e-9 Glioblastoma;Glioma; LIHC cis rs9457247 1.000 rs393558 chr6:167397750 A/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.25 -0.52 3.37e-25 Crohn's disease; LIHC cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -11.04 -0.51 1.96e-24 Platelet count; LIHC cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg09904177 chr6:26538194 HMGN4 0.57 11.21 0.52 4.92e-25 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg00280220 chr17:61926910 NA 0.42 6.79 0.34 4.88e-11 Prudent dietary pattern; LIHC cis rs10857712 0.754 rs7921041 chr10:135229239 G/C cg17796960 chr10:135278976 LOC619207 -0.34 -5.8 -0.3 1.53e-8 Systemic lupus erythematosus; LIHC cis rs7512552 0.839 rs1625468 chr1:150321486 G/A cg15654264 chr1:150340011 RPRD2 0.7 11.46 0.53 5.82e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs916888 0.773 rs199533 chr17:44828931 G/A cg12297030 chr17:43662878 NA -0.65 -6.27 -0.32 1.11e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2073300 0.609 rs6137913 chr20:23357725 C/T cg12062639 chr20:23401060 NAPB 1.01 13.63 0.59 4.25e-34 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs34779708 0.966 rs4934537 chr10:35441512 C/T cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7264396 0.690 rs2425170 chr20:34442672 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.58 -8.72 -0.43 1.24e-16 Total cholesterol levels; LIHC trans rs57221529 0.709 rs72706611 chr5:561146 C/A cg25482853 chr8:67687455 SGK3 0.67 6.66 0.34 1.09e-10 Lung disease severity in cystic fibrosis; LIHC cis rs738321 0.757 rs6001020 chr22:38538246 C/G cg25457927 chr22:38595422 NA -0.3 -6.88 -0.35 2.81e-11 Breast cancer; LIHC cis rs2832191 0.967 rs2251377 chr21:30530599 T/C cg24692254 chr21:30365293 RNF160 0.54 9.33 0.45 1.38e-18 Dental caries; LIHC cis rs9921222 0.500 rs8046256 chr16:393948 C/T cg26913058 chr16:419975 MRPL28 -0.47 -5.92 -0.3 7.88e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs9457247 0.967 rs385460 chr6:167403888 A/T cg23791538 chr6:167370224 RNASET2 -0.65 -11.02 -0.51 2.23e-24 Crohn's disease; LIHC cis rs867186 0.614 rs75076672 chr20:33451713 C/T cg08999081 chr20:33150536 PIGU 0.64 5.79 0.3 1.61e-8 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC cis rs28595532 0.800 rs111626798 chr4:119352517 C/T cg21605333 chr4:119757512 SEC24D 1.07 8.66 0.42 1.91e-16 Cannabis dependence symptom count; LIHC trans rs2270927 0.510 rs246814 chr5:75599208 C/T cg13563193 chr19:33072644 PDCD5 1.0 9.5 0.46 3.86e-19 Mean corpuscular volume; LIHC cis rs11971779 0.553 rs10269108 chr7:139106332 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs1005277 0.577 rs4934906 chr10:38015028 C/T cg25427524 chr10:38739819 LOC399744 -0.62 -11.95 -0.54 9.66e-28 Extrinsic epigenetic age acceleration; LIHC cis rs116095464 0.558 rs2288457 chr5:231270 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.61 -0.5 6.24e-23 Breast cancer; LIHC cis rs17106184 1.000 rs12088617 chr1:51347213 G/T cg07174182 chr1:51127561 FAF1 0.59 6.48 0.33 3.16e-10 Type 2 diabetes; LIHC cis rs4555082 0.874 rs2816621 chr14:105732762 A/T cg06808227 chr14:105710500 BRF1 -0.55 -7.11 -0.36 6.91e-12 Mean platelet volume;Platelet distribution width; LIHC trans rs66887589 0.616 rs6843509 chr4:120220196 G/A cg25214090 chr10:38739885 LOC399744 0.44 7.11 0.36 7.01e-12 Diastolic blood pressure; LIHC cis rs2050392 0.590 rs17547917 chr10:30718303 G/A cg02070205 chr10:30722105 MAP3K8 -0.43 -5.82 -0.3 1.35e-8 Inflammatory bowel disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03147627 chr4:83956202 COPS4 0.44 6.85 0.35 3.38e-11 Cognitive function; LIHC cis rs7584330 0.554 rs13411613 chr2:238437560 T/C cg08992911 chr2:238395768 MLPH 0.51 5.98 0.31 5.5e-9 Prostate cancer; LIHC cis rs2839186 0.632 rs17176110 chr21:47706535 C/A cg12379764 chr21:47803548 PCNT -0.59 -8.59 -0.42 3.1e-16 Testicular germ cell tumor; LIHC cis rs2839186 0.814 rs12482209 chr21:47664275 C/G cg13126279 chr21:47581558 C21orf56 0.45 7.18 0.36 4.28e-12 Testicular germ cell tumor; LIHC cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2354432 0.607 rs66486822 chr1:146802653 T/A cg25205988 chr1:146714368 CHD1L -0.9 -10.85 -0.51 8.86e-24 Mitochondrial DNA levels; LIHC cis rs904251 0.861 rs1757171 chr6:37487044 T/C cg08126542 chr6:37504118 NA -0.38 -6.08 -0.31 3.15e-9 Cognitive performance; LIHC cis rs7927592 0.871 rs113020558 chr11:68296832 G/A cg16797656 chr11:68205561 LRP5 0.52 8.25 0.41 3.44e-15 Total body bone mineral density; LIHC cis rs9296404 1 rs9296404 chr6:42925803 T/C cg05552183 chr6:42928497 GNMT 0.68 10.17 0.48 2.16e-21 Plasma homocysteine levels (post-methionine load test); LIHC cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg11764359 chr7:65958608 NA 0.59 6.01 0.31 4.75e-9 Diabetic kidney disease; LIHC cis rs79839061 0.610 rs11248051 chr4:858332 C/T cg07828340 chr4:882639 GAK 0.83 7.02 0.36 1.18e-11 Intelligence (multi-trait analysis); LIHC cis rs17685 0.725 rs6947068 chr7:75662056 T/C cg01364799 chr7:75623366 TMEM120A 0.5 7.65 0.38 2.04e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7647973 0.961 rs7626076 chr3:49298139 G/A cg07636037 chr3:49044803 WDR6 0.5 6.02 0.31 4.43e-9 Menarche (age at onset); LIHC cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg26119090 chr2:26468346 HADHA;HADHB -1.09 -16.98 -0.68 2.44e-47 Gut microbiome composition (summer); LIHC cis rs3762637 0.943 rs28403550 chr3:122251838 C/A cg24169773 chr3:122142474 KPNA1 -0.44 -8.84 -0.43 5.15e-17 LDL cholesterol levels; LIHC cis rs7212590 0.748 rs7213697 chr17:57903041 G/C cg10252138 chr17:58120427 NA -0.62 -6.11 -0.31 2.78e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg20887711 chr4:1340912 KIAA1530 0.78 12.23 0.55 9.18e-29 Longevity; LIHC cis rs9910055 0.529 rs190144 chr17:42164584 A/G cg19774624 chr17:42201019 HDAC5 0.49 5.85 0.3 1.13e-8 Total body bone mineral density; LIHC cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg12016809 chr21:47604291 C21orf56 0.44 6.59 0.34 1.62e-10 Testicular germ cell tumor; LIHC cis rs7917772 0.582 rs4285804 chr10:104386309 T/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.45 -6.62 -0.34 1.37e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs10456809 0.808 rs6918261 chr6:17815431 A/G cg24822696 chr6:125283245 STL -0.38 -6.22 -0.32 1.43e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs7131987 0.903 rs11050163 chr12:29420398 C/T cg16970926 chr12:29381810 FAR2 0.31 6.59 0.34 1.7e-10 QT interval; LIHC trans rs911555 0.755 rs6575988 chr14:103900827 G/T cg17675199 chr6:35436792 RPL10A -0.41 -8.5 -0.42 5.82e-16 Intelligence (multi-trait analysis); LIHC cis rs72781680 1.000 rs72796337 chr2:24142957 G/A cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg07424592 chr7:64974309 NA 0.82 9.56 0.46 2.36e-19 Diabetic kidney disease; LIHC cis rs10927875 0.632 rs10927864 chr1:16165661 C/G cg07117364 chr1:16154769 NA -0.38 -6.8 -0.35 4.61e-11 Dilated cardiomyopathy; LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg09367891 chr1:107599246 PRMT6 -0.72 -11.91 -0.54 1.32e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12701220 0.894 rs12701348 chr7:1039457 C/T cg00990874 chr7:1149470 C7orf50 -0.64 -9.05 -0.44 1.09e-17 Bronchopulmonary dysplasia; LIHC cis rs55665837 0.540 rs3206554 chr11:14797945 A/T cg00085434 chr11:14927489 NA 0.4 5.78 0.3 1.65e-8 Vitamin D levels; LIHC cis rs6912958 0.535 rs448580 chr6:88040399 A/C cg12350822 chr6:88032061 C6orf162;GJB7 0.35 6.77 0.34 5.75e-11 Monocyte percentage of white cells; LIHC cis rs7618915 0.547 rs11714419 chr3:52628816 A/G cg10802521 chr3:52805072 NEK4 -0.43 -7.11 -0.36 7.03e-12 Bipolar disorder; LIHC cis rs1401999 0.606 rs939335 chr3:183745663 A/G cg01324343 chr3:183735012 ABCC5 0.62 9.87 0.47 2.16e-20 Anterior chamber depth; LIHC cis rs7412746 0.611 rs16827671 chr1:150738759 T/C cg18016565 chr1:150552671 MCL1 0.54 10.13 0.48 2.88e-21 Melanoma; LIHC cis rs4665809 1.000 rs1371553 chr2:26262948 G/A cg04944784 chr2:26401820 FAM59B -0.71 -8.92 -0.43 2.85e-17 Gut microbiome composition (summer); LIHC cis rs3736485 0.966 rs2414111 chr15:51901357 A/G cg08986416 chr15:51914746 DMXL2 0.41 6.12 0.31 2.59e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9303280 0.806 rs10852935 chr17:38031674 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.77 0.3 1.76e-8 Self-reported allergy; LIHC cis rs12971120 1.000 rs12971120 chr18:72174023 A/G cg26446133 chr18:72167187 CNDP2 -0.79 -14.8 -0.62 1.23e-38 Refractive error; LIHC cis rs425277 0.606 rs451061 chr1:2075068 C/G cg03732007 chr1:2071316 PRKCZ 0.37 6.35 0.32 7.05e-10 Height; LIHC cis rs6951245 0.882 rs11764817 chr7:1064610 T/C cg08132940 chr7:1081526 C7orf50 -0.63 -6.05 -0.31 3.74e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg13393036 chr8:95962371 TP53INP1 -0.37 -8.55 -0.42 4.1e-16 Type 2 diabetes; LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg13752114 chr3:195489708 MUC4 0.68 11.35 0.52 1.53e-25 Lung disease severity in cystic fibrosis; LIHC cis rs1728785 1.000 rs1728801 chr16:68571457 A/C cg02972257 chr16:68554789 NA -0.56 -6.45 -0.33 3.89e-10 Ulcerative colitis; LIHC cis rs2576037 0.526 rs3892820 chr18:44479558 A/G cg19077165 chr18:44547161 KATNAL2 -0.45 -6.79 -0.34 4.89e-11 Personality dimensions; LIHC cis rs7208859 0.623 rs12006 chr17:29110652 G/A cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9393692 0.846 rs9366651 chr6:26336696 G/T cg13736514 chr6:26305472 NA -0.36 -5.98 -0.31 5.61e-9 Educational attainment; LIHC cis rs249954 0.512 rs249856 chr16:23658976 G/A cg05131483 chr16:23706242 ERN2 0.36 5.85 0.3 1.14e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7772486 0.875 rs2748502 chr6:146298239 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.82 -0.3 1.36e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 0.850 rs62054599 chr16:89808850 C/G cg00800038 chr16:89945340 TCF25 -0.61 -8.89 -0.43 3.56e-17 Skin colour saturation; LIHC cis rs3736594 0.879 rs4666011 chr2:27980912 G/C cg27432699 chr2:27873401 GPN1 0.4 6.17 0.32 1.93e-9 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg23978390 chr7:1156363 C7orf50 0.53 8.23 0.41 3.93e-15 Longevity;Endometriosis; LIHC cis rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17971929 chr21:40555470 PSMG1 -0.48 -7.12 -0.36 6.34e-12 Cognitive function; LIHC trans rs78049276 0.651 rs59415853 chr4:148378225 G/A cg13149281 chr14:23389818 RBM23;PRMT5 -0.66 -8.27 -0.41 2.92e-15 Pulse pressure; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg19819135 chr1:70710422 SFRS11 0.4 6.46 0.33 3.64e-10 Longevity; LIHC cis rs66887589 0.934 rs7672519 chr4:120544112 C/T cg09307838 chr4:120376055 NA -0.46 -6.86 -0.35 3.32e-11 Diastolic blood pressure; LIHC cis rs2228479 0.702 rs62053702 chr16:89860688 G/T cg00800038 chr16:89945340 TCF25 -0.61 -8.68 -0.42 1.69e-16 Skin colour saturation; LIHC cis rs10752881 0.933 rs2027086 chr1:183057933 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.59 0.5 7.57e-23 Colorectal cancer; LIHC cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg25072359 chr17:41440525 NA 0.4 6.36 0.33 6.46e-10 Menopause (age at onset); LIHC cis rs9378688 0.654 rs2505660 chr6:2326441 A/G cg12303981 chr6:2244766 GMDS -0.43 -6.08 -0.31 3.21e-9 Caudate nucleus volume; LIHC cis rs9926296 0.607 rs2079672 chr16:89884917 A/G cg27121462 chr16:89883253 FANCA -0.47 -7.86 -0.39 4.88e-14 Vitiligo; LIHC cis rs1800469 1.000 rs1549933 chr19:41871142 A/G cg08477640 chr19:41863820 B9D2 0.35 5.76 0.3 1.9e-8 Colorectal cancer; LIHC cis rs4638749 0.677 rs1563112 chr2:108850579 C/T cg25838818 chr2:108905173 SULT1C2 -0.38 -6.68 -0.34 9.56e-11 Blood pressure; LIHC cis rs4407350 0.837 rs4823326 chr22:44908678 C/T cg11695653 chr22:44894386 LDOC1L -0.36 -6.15 -0.32 2.16e-9 Intelligence (multi-trait analysis); LIHC cis rs2705520 0.744 rs1814052 chr3:112231907 C/T cg09473763 chr3:112282684 SLC35A5 -0.74 -8.93 -0.43 2.61e-17 Asthma (childhood onset); LIHC cis rs11098499 0.913 rs11098496 chr4:120167466 C/G cg09307838 chr4:120376055 NA 0.75 11.08 0.51 1.43e-24 Corneal astigmatism; LIHC cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs35110281 0.837 rs7279968 chr21:45077398 C/G cg01579765 chr21:45077557 HSF2BP -0.31 -6.05 -0.31 3.76e-9 Mean corpuscular volume; LIHC cis rs7208859 0.623 rs11652358 chr17:29205480 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs317689 0.608 rs650198 chr12:69674595 C/T cg22834771 chr12:69754056 YEATS4 -0.41 -6.08 -0.31 3.27e-9 Response to diuretic therapy; LIHC cis rs10256972 0.630 rs10282584 chr7:1081442 C/T cg07308232 chr7:1071921 C7orf50 -0.39 -5.98 -0.31 5.55e-9 Longevity;Endometriosis; LIHC cis rs763121 0.853 rs6519124 chr22:39045099 T/C cg21395723 chr22:39101663 GTPBP1 0.41 7.0 0.35 1.35e-11 Menopause (age at onset); LIHC cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs60843830 1.000 rs3791223 chr2:222336 T/C cg11347411 chr7:150020925 ACTR3C;LRRC61 0.61 8.79 0.43 7.58e-17 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs10792665 0.606 rs1939133 chr11:82602895 C/T cg24227371 chr11:82718527 RAB30 -0.27 -6.1 -0.31 2.94e-9 Obesity-related traits; LIHC cis rs738322 1.000 rs4379 chr22:38569171 T/C cg25457927 chr22:38595422 NA -0.26 -6.36 -0.33 6.6e-10 Cutaneous nevi; LIHC cis rs4820539 1.000 rs4820539 chr22:23477970 C/T cg21100191 chr22:23484243 RTDR1 -0.86 -15.61 -0.65 7.28e-42 Bone mineral density; LIHC trans rs8002861 0.935 rs7319725 chr13:44445421 T/C cg17145862 chr1:211918768 LPGAT1 0.58 10.93 0.51 4.58e-24 Leprosy; LIHC cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg06238570 chr21:40685208 BRWD1 0.62 7.58 0.38 3.3e-13 Cognitive function; LIHC cis rs709400 0.663 rs1028613 chr14:103888324 G/A cg26031613 chr14:104095156 KLC1 0.79 10.32 0.49 6.46e-22 Body mass index; LIHC cis rs10131894 0.575 rs1860935 chr14:75432464 G/A cg08847533 chr14:75593920 NEK9 0.8 14.99 0.63 2.2e-39 Coronary artery disease; LIHC cis rs2075165 0.901 rs1043165 chr1:156220056 T/C cg20302342 chr1:156215951 PAQR6 0.32 6.03 0.31 4.22e-9 Tonsillectomy; LIHC cis rs2279817 0.731 rs11203435 chr1:18010233 T/A cg21791023 chr1:18019539 ARHGEF10L -0.42 -5.86 -0.3 1.09e-8 Neuroticism; LIHC cis rs2645694 0.533 rs2645681 chr4:77820949 G/A cg06046430 chr4:77819534 ANKRD56 0.5 6.53 0.33 2.34e-10 Emphysema distribution in smoking; LIHC cis rs11122272 0.675 rs1416913 chr1:231533206 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.94e-23 Hemoglobin concentration; LIHC cis rs8141529 0.702 rs8137262 chr22:29292135 C/T cg02153584 chr22:29168773 CCDC117 0.51 8.0 0.4 1.89e-14 Lymphocyte counts; LIHC cis rs68170813 0.559 rs6947675 chr7:106817184 T/C cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs244293 0.801 rs11655949 chr17:53169883 A/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.59 0.38 3.01e-13 Menarche (age at onset); LIHC cis rs9513627 0.920 rs73556201 chr13:100128753 C/G cg25919922 chr13:100150906 NA -0.77 -6.89 -0.35 2.74e-11 Obesity-related traits; LIHC cis rs17685 0.712 rs10275521 chr7:75770972 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs611744 0.870 rs2212703 chr8:109198401 G/C cg18478394 chr8:109455254 TTC35 0.41 6.73 0.34 7.31e-11 Dupuytren's disease; LIHC cis rs546131 0.642 rs61881107 chr11:34848020 A/C cg11058730 chr11:34937778 PDHX;APIP -0.53 -6.53 -0.33 2.4e-10 Lung disease severity in cystic fibrosis; LIHC cis rs801193 0.569 rs13242290 chr7:66121885 G/A cg11764359 chr7:65958608 NA -0.75 -12.75 -0.57 1.03e-30 Aortic root size; LIHC cis rs892961 0.932 rs7207891 chr17:75413922 G/C cg05865280 chr17:75406074 SEPT9 0.64 13.12 0.58 4.06e-32 Airflow obstruction; LIHC cis rs1559088 0.948 rs7257858 chr19:33591231 T/C cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs11711311 0.955 rs3796254 chr3:113380332 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.35 -5.76 -0.3 1.89e-8 IgG glycosylation; LIHC cis rs2439831 0.867 rs16957627 chr15:43642657 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs9291683 0.517 rs11736479 chr4:10017387 G/C cg11266682 chr4:10021025 SLC2A9 0.33 7.15 0.36 5.29e-12 Bone mineral density; LIHC cis rs60871478 1.000 rs62432861 chr7:807649 G/A cg13844804 chr7:814759 HEATR2 0.44 5.88 0.3 9.97e-9 Cerebrospinal P-tau181p levels; LIHC cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg10802521 chr3:52805072 NEK4 -0.34 -5.72 -0.3 2.3e-8 Bipolar disorder; LIHC cis rs561341 0.769 rs8074383 chr17:30178793 C/T cg13647721 chr17:30228624 UTP6 -0.78 -6.61 -0.34 1.5e-10 Hip circumference adjusted for BMI; LIHC cis rs2302190 0.882 rs3803751 chr17:56650356 A/G cg12560992 chr17:57184187 TRIM37 0.68 8.8 0.43 7e-17 Vitamin D levels; LIHC cis rs526231 0.547 rs72783895 chr5:102287496 C/A cg23492399 chr5:102201601 PAM -0.45 -6.75 -0.34 6.18e-11 Primary biliary cholangitis; LIHC cis rs2997447 0.655 rs12059101 chr1:26384013 A/G cg19633962 chr1:26362018 EXTL1 -0.86 -9.37 -0.45 1.01e-18 QRS complex (12-leadsum); LIHC cis rs10832963 0.961 rs10832954 chr11:18643559 G/A cg20219074 chr11:18656078 SPTY2D1 0.84 14.02 0.6 1.29e-35 Breast cancer; LIHC cis rs6831352 0.842 rs1230156 chr4:99989626 C/T cg12011299 chr4:100065546 ADH4 0.59 9.83 0.47 3.09e-20 Alcohol dependence; LIHC cis rs988712 0.537 rs10742179 chr11:27650524 A/G cg18117895 chr11:27722066 BDNF -0.46 -6.57 -0.33 1.88e-10 Obesity; LIHC cis rs10791097 0.667 rs1893019 chr11:130756664 C/G cg14779329 chr11:130786720 SNX19 0.42 6.34 0.32 7.1e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12478296 1.000 rs56323081 chr2:243040807 A/G cg06360820 chr2:242988706 NA -0.94 -12.3 -0.55 4.98e-29 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06808467 chr18:5237767 LOC339290;C18orf18 0.59 7.79 0.39 8.17e-14 Lung function (FEV1/FVC); LIHC cis rs7772486 0.790 rs7753696 chr6:146279098 G/T cg05347473 chr6:146136440 FBXO30 -0.38 -5.92 -0.31 7.64e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.506 rs4822020 chr22:41700203 C/T cg03806693 chr22:41940476 POLR3H -0.71 -8.44 -0.42 8.82e-16 Vitiligo; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg12419862 chr22:24373484 LOC391322 -0.68 -10.09 -0.48 4e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2235573 0.551 rs84770 chr22:38390128 T/G cg03989125 chr22:38214979 NA -0.44 -6.14 -0.32 2.25e-9 Glioblastoma;Glioma; LIHC cis rs4970988 0.640 rs7524734 chr1:150655686 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.25 0.32 1.19e-9 Urate levels; LIHC cis rs8180040 0.681 rs9818382 chr3:47193034 C/T cg27129171 chr3:47204927 SETD2 0.58 9.54 0.46 2.83e-19 Colorectal cancer; LIHC cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg20607798 chr8:58055168 NA 0.68 7.75 0.39 1.04e-13 Developmental language disorder (linguistic errors); LIHC cis rs7095607 0.560 rs2101484 chr10:69927711 T/C cg18986048 chr10:69913749 MYPN 0.48 7.2 0.36 3.76e-12 Lung function (FVC); LIHC trans rs1814175 0.615 rs10839378 chr11:49806943 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.91 0.35 2.35e-11 Height; LIHC cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg16606324 chr3:10149918 C3orf24 -0.5 -5.82 -0.3 1.37e-8 Alzheimer's disease; LIHC cis rs597539 0.690 rs647661 chr11:68625875 T/C cg04772025 chr11:68637568 NA 0.45 5.89 0.3 9.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24504843 chr4:56896641 CEP135 -0.44 -6.61 -0.34 1.51e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.59 8.99 0.44 1.76e-17 Height; LIHC cis rs2274273 0.805 rs10131926 chr14:55713246 T/C cg01864836 chr14:55583639 NA -0.44 -8.27 -0.41 3.04e-15 Protein biomarker; LIHC cis rs67460515 0.563 rs7618924 chr3:160855599 A/G cg03342759 chr3:160939853 NMD3 -0.63 -9.41 -0.45 7.59e-19 Parkinson's disease; LIHC cis rs17270561 0.666 rs1937129 chr6:25789132 A/G cg17691542 chr6:26056736 HIST1H1C 0.41 5.74 0.3 2.09e-8 Iron status biomarkers; LIHC cis rs1862618 0.641 rs252893 chr5:56224714 T/C cg12311346 chr5:56204834 C5orf35 -0.46 -6.27 -0.32 1.09e-9 Initial pursuit acceleration; LIHC cis rs11630290 0.736 rs7174738 chr15:64144813 A/T cg12036633 chr15:63758958 NA -0.56 -5.75 -0.3 2e-8 Iris characteristics; LIHC cis rs2836974 0.666 rs11910705 chr21:40685604 C/T cg17971929 chr21:40555470 PSMG1 -0.45 -6.74 -0.34 6.88e-11 Cognitive function; LIHC cis rs8017423 0.900 rs7141887 chr14:90705364 G/T cg14092571 chr14:90743983 NA -0.37 -5.88 -0.3 9.66e-9 Mortality in heart failure; LIHC cis rs9916302 0.904 rs1077715 chr17:37683548 A/T cg15445000 chr17:37608096 MED1 0.38 5.75 0.3 1.96e-8 Glomerular filtration rate (creatinine); LIHC cis rs8114671 0.967 rs1415774 chr20:33765616 C/T cg07148914 chr20:33460835 GGT7 -0.42 -5.83 -0.3 1.3e-8 Height; LIHC cis rs3849570 1.000 rs6548773 chr3:81840222 C/T cg07356753 chr3:81810745 GBE1 0.63 10.44 0.49 2.46e-22 Waist circumference;Body mass index; LIHC cis rs1005277 0.579 rs2474575 chr10:38387901 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs10504073 0.584 rs7823690 chr8:49943831 G/A cg00325661 chr8:49890786 NA 0.34 7.78 0.39 8.88e-14 Blood metabolite ratios; LIHC cis rs514406 0.570 rs1332776 chr1:53189816 C/T cg24675658 chr1:53192096 ZYG11B -0.67 -10.79 -0.5 1.53e-23 Monocyte count; LIHC cis rs992157 1.000 rs2292553 chr2:219146803 G/A cg00012203 chr2:219082015 ARPC2 0.88 14.31 0.61 1.02e-36 Colorectal cancer; LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg19016816 chr7:1267987 NA -0.26 -5.74 -0.3 2.03e-8 Bipolar disorder and schizophrenia; LIHC cis rs3096299 0.606 rs8052103 chr16:89541243 A/T cg06640241 chr16:89574553 SPG7 -0.63 -9.42 -0.45 7.01e-19 Multiple myeloma (IgH translocation); LIHC cis rs11711311 0.747 rs11928494 chr3:113343219 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.34 -6.16 -0.32 2.09e-9 IgG glycosylation; LIHC cis rs7666738 0.546 rs17546687 chr4:98769266 T/A cg05340658 chr4:99064831 C4orf37 0.47 6.06 0.31 3.62e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg18306943 chr3:40428807 ENTPD3 -0.4 -7.21 -0.36 3.67e-12 Renal cell carcinoma; LIHC cis rs600806 0.850 rs10858095 chr1:109962642 G/C cg02415029 chr1:110025642 ATXN7L2 -0.46 -5.78 -0.3 1.65e-8 Intelligence (multi-trait analysis); LIHC cis rs611744 0.967 rs591792 chr8:109200446 T/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs4629710 0.592 rs35017713 chr6:131581212 G/A cg12606694 chr6:131520996 AKAP7 0.62 7.19 0.36 4.22e-12 Multiple myeloma (IgH translocation); LIHC cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC cis rs2404602 0.583 rs35707798 chr15:76565026 G/C cg03037974 chr15:76606532 NA 0.89 22.97 0.78 2.62e-71 Blood metabolite levels; LIHC trans rs9914544 0.545 rs9912568 chr17:18792719 G/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.46 -0.33 3.65e-10 Educational attainment (years of education); LIHC cis rs4727027 0.705 rs10952803 chr7:148890091 T/G cg23583168 chr7:148888333 NA -0.82 -11.87 -0.54 1.94e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg13152130 chr6:118910203 C6orf204 -0.65 -7.47 -0.37 6.87e-13 Diastolic blood pressure; LIHC cis rs1008375 1.000 rs6846238 chr4:17629939 A/G cg16339924 chr4:17578868 LAP3 0.45 6.31 0.32 8.47e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs921968 0.565 rs7586384 chr2:219582897 T/C cg02985541 chr2:219472218 PLCD4 -0.38 -6.59 -0.34 1.67e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6690583 0.623 rs893618 chr1:85513770 C/T cg22153463 chr1:85462885 MCOLN2 0.53 6.22 0.32 1.43e-9 Serum sulfate level; LIHC cis rs4808199 0.895 rs4808194 chr19:19435680 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.54 7.81 0.39 6.96e-14 Nonalcoholic fatty liver disease; LIHC cis rs7512552 0.839 rs1498308 chr1:150295131 G/T cg15654264 chr1:150340011 RPRD2 0.69 11.88 0.54 1.68e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs7208859 0.623 rs1061342 chr17:29114463 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.18 0.4 5.47e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6942756 0.774 rs2566876 chr7:128890055 A/G cg02491457 chr7:128862824 NA 0.66 10.59 0.5 7.23e-23 White matter hyperintensity burden; LIHC cis rs8072100 1.000 rs7210738 chr17:45757598 G/A cg08085267 chr17:45401833 C17orf57 0.58 8.44 0.42 9.01e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg12463550 chr7:65579703 CRCP -0.67 -6.99 -0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs7312933 0.558 rs61926593 chr12:42818912 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.87 0.39 4.64e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs7615952 0.800 rs12489350 chr3:125644116 T/C cg07211511 chr3:129823064 LOC729375 -0.84 -10.53 -0.49 1.2e-22 Blood pressure (smoking interaction); LIHC cis rs1005277 0.563 rs2505216 chr10:38482830 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.44 -6.28 -0.32 1.02e-9 Extrinsic epigenetic age acceleration; LIHC cis rs9640161 0.789 rs3735174 chr7:150020489 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.38 -0.41 1.37e-15 Blood protein levels;Circulating chemerin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27590859 chr20:54967608 AURKA;CSTF1 0.43 6.1 0.31 2.87e-9 Lung function (FEV1/FVC); LIHC cis rs17854409 0.536 rs3765464 chr20:61485236 T/C cg07645718 chr20:61493192 TCFL5 0.68 5.87 0.3 1.01e-8 Obesity-related traits; LIHC cis rs60871478 0.838 rs7789321 chr7:800977 A/G cg04727924 chr7:799746 HEATR2 -0.62 -8.41 -0.41 1.1e-15 Cerebrospinal P-tau181p levels; LIHC cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg18357526 chr6:26021779 HIST1H4A -0.38 -5.82 -0.3 1.32e-8 Height; LIHC cis rs950776 0.518 rs4887063 chr15:78839715 C/T cg06917634 chr15:78832804 PSMA4 -0.88 -12.9 -0.57 2.81e-31 Sudden cardiac arrest; LIHC cis rs11148252 0.553 rs9536219 chr13:53227301 C/T cg00495681 chr13:53174319 NA 0.69 12.0 0.54 6.31e-28 Lewy body disease; LIHC cis rs7927592 0.956 rs7944870 chr11:68309108 C/G cg16797656 chr11:68205561 LRP5 0.52 8.34 0.41 1.82e-15 Total body bone mineral density; LIHC cis rs477692 1.000 rs4750759 chr10:131436603 G/A cg19680672 chr10:131412579 MGMT 0.43 6.53 0.33 2.38e-10 Response to temozolomide; LIHC cis rs9649213 0.555 rs12667634 chr7:97965442 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.9 -0.3 8.87e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs7587476 0.505 rs777323 chr2:215738485 A/G cg04004882 chr2:215674386 BARD1 -0.51 -7.06 -0.36 9.41e-12 Neuroblastoma; LIHC cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -13.94 -0.6 2.78e-35 Alzheimer's disease; LIHC cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg05896524 chr21:47604654 C21orf56 0.51 8.05 0.4 1.42e-14 Testicular germ cell tumor; LIHC trans rs1728785 1.000 rs1728785 chr16:68591230 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.53 -6.64 -0.34 1.24e-10 Ulcerative colitis; LIHC cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg20887711 chr4:1340912 KIAA1530 -0.49 -7.57 -0.38 3.61e-13 Obesity-related traits; LIHC cis rs60871478 1.000 rs12531530 chr7:827366 T/C cg05535760 chr7:792225 HEATR2 0.89 11.69 0.53 8.84e-27 Cerebrospinal P-tau181p levels; LIHC cis rs600806 0.778 rs2152924 chr1:110011701 G/A cg23091122 chr1:110024289 SYPL2 -0.5 -6.78 -0.34 5.27e-11 Intelligence (multi-trait analysis); LIHC cis rs7762018 0.655 rs2184194 chr6:170148394 C/T cg19338460 chr6:170058176 WDR27 -0.38 -5.9 -0.3 8.61e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7208859 0.623 rs56378576 chr17:29010120 C/T cg13385521 chr17:29058706 SUZ12P 0.67 6.4 0.33 5.05e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7520050 0.966 rs7540325 chr1:46338217 A/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2204008 0.774 rs11514062 chr12:38332297 A/C cg26384229 chr12:38710491 ALG10B 0.59 8.09 0.4 1.05e-14 Bladder cancer; LIHC cis rs2304069 0.601 rs216143 chr5:149444147 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.8 10.13 0.48 2.81e-21 HIV-1 control; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg07677032 chr17:61819896 STRADA -0.43 -6.34 -0.32 7.28e-10 Prudent dietary pattern; LIHC cis rs28595532 0.545 rs13132957 chr4:119250841 G/C cg21605333 chr4:119757512 SEC24D 0.79 6.65 0.34 1.19e-10 Cannabis dependence symptom count; LIHC cis rs916888 0.773 rs199533 chr17:44828931 G/A cg15921436 chr17:44337874 NA 0.64 6.53 0.33 2.42e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1728785 1.000 rs1645979 chr16:68603660 G/T cg02972257 chr16:68554789 NA -0.56 -6.4 -0.33 5.27e-10 Ulcerative colitis; LIHC cis rs67311347 1.000 rs56992941 chr3:40472434 A/T cg24209194 chr3:40518798 ZNF619 0.46 6.84 0.35 3.57e-11 Renal cell carcinoma; LIHC cis rs9611565 0.559 rs7290990 chr22:41964357 C/A cg03806693 chr22:41940476 POLR3H -0.87 -9.75 -0.47 5.67e-20 Vitiligo; LIHC cis rs8192917 0.887 rs2236337 chr14:25100247 T/C cg08766149 chr14:25103301 GZMB 0.31 7.33 0.37 1.69e-12 Vitiligo; LIHC cis rs4665809 1.000 rs6546767 chr2:26328746 A/G cg27170947 chr2:26402098 FAM59B -0.65 -8.22 -0.41 4.22e-15 Gut microbiome composition (summer); LIHC cis rs7927771 0.524 rs754434 chr11:47814280 A/G cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC cis rs2228479 0.850 rs11641552 chr16:89838700 C/A cg00800038 chr16:89945340 TCF25 -0.64 -9.57 -0.46 2.29e-19 Skin colour saturation; LIHC cis rs72781680 1.000 rs7588286 chr2:24071427 A/G cg08917208 chr2:24149416 ATAD2B 0.85 8.12 0.4 8.32e-15 Lymphocyte counts; LIHC cis rs4660306 1.000 rs4660870 chr1:45995231 T/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.62 -0.34 1.37e-10 Homocysteine levels; LIHC cis rs903552 0.800 rs1587107 chr15:102006485 T/C cg19295451 chr15:102010161 PCSK6 -0.52 -7.08 -0.36 8.29e-12 Diabetic kidney disease; LIHC trans rs875971 1.000 rs709597 chr7:65825983 A/G cg10756647 chr7:56101905 PSPH -0.43 -6.27 -0.32 1.07e-9 Aortic root size; LIHC cis rs700651 0.789 rs10190226 chr2:198901564 A/G cg03934865 chr2:198174659 NA -0.45 -6.37 -0.33 6.09e-10 Intracranial aneurysm; LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs7089973 0.604 rs7923693 chr10:116619566 A/G cg23260525 chr10:116636907 FAM160B1 0.39 7.71 0.38 1.4e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs739401 0.619 rs10766480 chr11:2961325 G/A cg20651018 chr11:3035856 CARS -0.35 -5.87 -0.3 1.04e-8 Longevity; LIHC cis rs7223966 1.000 rs8076717 chr17:61850301 C/T cg05941027 chr17:61774174 LIMD2 -0.36 -7.38 -0.37 1.23e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs5769765 1.000 rs910800 chr22:50278642 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.2 0.45 3.71e-18 Schizophrenia; LIHC trans rs1814175 0.645 rs1851853 chr11:49953434 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs7534824 0.543 rs61780299 chr1:101403471 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.44 0.37 8.3e-13 Refractive astigmatism; LIHC cis rs1707322 1.000 rs12077546 chr1:46431806 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.35 0.32 7.05e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg03806693 chr22:41940476 POLR3H -1.09 -11.69 -0.53 8.49e-27 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg05564831 chr3:52568323 NT5DC2 0.35 5.94 0.31 6.87e-9 Electroencephalogram traits; LIHC cis rs11785400 1.000 rs4736365 chr8:143742197 A/G cg24634471 chr8:143751801 JRK 0.51 8.23 0.41 4.08e-15 Schizophrenia; LIHC cis rs965469 1.000 rs6051709 chr20:3263685 T/C cg25506879 chr20:3388711 C20orf194 -0.57 -6.88 -0.35 2.95e-11 IFN-related cytopenia; LIHC cis rs9457247 0.934 rs2345571 chr6:167403400 T/G cg12798992 chr6:167411361 FGFR1OP 0.6 10.0 0.48 8.15e-21 Crohn's disease; LIHC trans rs4146653 0.608 rs1901639 chr10:4763871 A/T cg25345178 chr8:72459908 NA 0.32 6.05 0.31 3.75e-9 Major depressive disorder; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T ch.2.2322915R chr2:111420003 BUB1 -0.4 -6.68 -0.34 9.5e-11 Hepatitis; LIHC cis rs7927771 0.965 rs4752845 chr11:47539697 T/C cg18512352 chr11:47633146 NA -0.26 -6.06 -0.31 3.5e-9 Subjective well-being; LIHC cis rs7845219 0.597 rs7002058 chr8:95873993 G/C cg13393036 chr8:95962371 TP53INP1 -0.36 -7.9 -0.39 3.75e-14 Type 2 diabetes; LIHC cis rs7408868 1.000 rs10415431 chr19:15277027 G/A cg09752223 chr19:15281200 NOTCH3 -0.37 -5.89 -0.3 9.39e-9 Pulse pressure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15965583 chr1:150601949 ENSA 0.41 6.61 0.34 1.47e-10 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01423368 chr11:76155379 C11orf30 0.44 6.14 0.32 2.32e-9 Pancreatic cancer; LIHC cis rs4919087 0.590 rs701821 chr10:99038562 G/A cg25902810 chr10:99078978 FRAT1 -0.6 -6.68 -0.34 9.41e-11 Monocyte count; LIHC cis rs12922317 0.927 rs12923439 chr16:12073958 C/T cg09319797 chr16:12061715 TNFRSF17 0.41 7.29 0.37 2.2e-12 Schizophrenia; LIHC cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.58 -0.34 1.79e-10 Gut microbiome composition (summer); LIHC cis rs7914558 0.901 rs1926034 chr10:104829102 G/A cg15744005 chr10:104629667 AS3MT -0.37 -8.08 -0.4 1.14e-14 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7542091 0.635 rs985431 chr1:210043948 A/T cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs6540556 0.682 rs11119332 chr1:209892960 C/T cg05527609 chr1:210001259 C1orf107 -0.55 -7.65 -0.38 2.09e-13 Red blood cell count; LIHC cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 9.46 0.46 5.22e-19 Mean platelet volume; LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs17711722 0.653 rs2460421 chr7:65491123 A/T cg14393609 chr7:65229607 NA -0.39 -6.21 -0.32 1.5e-9 Calcium levels; LIHC cis rs2404602 0.735 rs2468130 chr15:76796496 T/C cg03037974 chr15:76606532 NA -0.58 -9.89 -0.47 1.93e-20 Blood metabolite levels; LIHC cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg22508957 chr16:3507546 NAT15 0.45 8.62 0.42 2.55e-16 Tuberculosis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08522707 chr7:140714747 MRPS33 -0.57 -6.55 -0.33 2.12e-10 Systolic blood pressure; LIHC cis rs7903847 0.620 rs11189168 chr10:99125769 T/C cg08345082 chr10:99160200 RRP12 -0.35 -5.95 -0.31 6.69e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs8072100 0.875 rs62073966 chr17:45600013 T/A cg08085267 chr17:45401833 C17orf57 0.56 8.39 0.41 1.3e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs9914544 0.545 rs9914914 chr17:18787780 G/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.57 -0.33 1.82e-10 Educational attainment (years of education); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg16674323 chr3:42846108 HIGD1A 0.5 6.34 0.32 7.1e-10 Hepatitis; LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs4919694 1.000 rs12252500 chr10:104794984 G/C cg04362960 chr10:104952993 NT5C2 1.15 9.07 0.44 9.6e-18 Arsenic metabolism; LIHC cis rs28595532 0.623 rs34958556 chr4:119222074 C/T cg21605333 chr4:119757512 SEC24D 0.8 6.78 0.34 5.13e-11 Cannabis dependence symptom count; LIHC cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.11 0.31 2.7e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.62 -11.99 -0.54 7.02e-28 Prudent dietary pattern; LIHC cis rs6582630 0.502 rs11495393 chr12:38341194 T/C cg26384229 chr12:38710491 ALG10B 0.57 7.96 0.4 2.61e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs7072216 0.763 rs733346 chr10:100164325 A/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.46 -0.33 3.51e-10 Metabolite levels; LIHC cis rs6840360 0.967 rs1511170 chr4:152701110 A/G cg22705602 chr4:152727874 NA -0.35 -7.47 -0.37 6.9e-13 Intelligence (multi-trait analysis); LIHC cis rs6062302 0.522 rs4809312 chr20:62234240 C/T cg06363034 chr20:62225388 GMEB2 -0.44 -7.52 -0.38 4.94e-13 Glioblastoma; LIHC cis rs5769765 0.955 rs8139758 chr22:50261123 G/T cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs4237845 0.780 rs3751331 chr12:58290278 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.44 6.19 0.32 1.73e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg11062466 chr8:58055876 NA 0.51 7.49 0.38 5.87e-13 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg13395646 chr4:1353034 KIAA1530 -0.63 -9.0 -0.44 1.55e-17 Obesity-related traits; LIHC cis rs3857067 0.806 rs10008044 chr4:95092850 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.55 -0.38 4.03e-13 QT interval; LIHC cis rs3770081 1.000 rs75109362 chr2:86289889 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.84 -8.59 -0.42 3.03e-16 Facial emotion recognition (sad faces); LIHC cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.75e-9 Menopause (age at onset); LIHC cis rs9303401 0.614 rs35308719 chr17:57163501 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.9 0.54 1.54e-27 Cognitive test performance; LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg26338869 chr17:61819248 STRADA 0.53 7.03 0.36 1.15e-11 Height; LIHC cis rs9733 0.536 rs10888385 chr1:150574302 T/C cg17724175 chr1:150552817 MCL1 -0.37 -7.45 -0.37 7.54e-13 Tonsillectomy; LIHC trans rs7618501 0.602 rs34831713 chr3:50118748 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.14 -0.44 5.47e-18 Intelligence (multi-trait analysis); LIHC cis rs919433 0.679 rs7564924 chr2:198513877 C/T cg10820045 chr2:198174542 NA 0.45 7.12 0.36 6.57e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11764590 0.666 rs7787359 chr7:2090849 A/G cg23043544 chr7:2124092 MAD1L1 -0.4 -6.52 -0.33 2.49e-10 Neuroticism; LIHC cis rs9303401 0.538 rs10515155 chr17:56481944 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.79 10.18 0.48 1.95e-21 Cognitive test performance; LIHC cis rs9393777 0.588 rs6926677 chr6:26478825 G/C cg12826209 chr6:26865740 GUSBL1 0.66 7.9 0.39 3.78e-14 Intelligence (multi-trait analysis); LIHC cis rs9911578 0.967 rs7214892 chr17:57065401 G/A cg05425664 chr17:57184151 TRIM37 -0.56 -8.16 -0.4 6.61e-15 Intelligence (multi-trait analysis); LIHC cis rs4132509 0.744 rs10803156 chr1:243917776 G/C cg21452805 chr1:244014465 NA 0.45 5.81 0.3 1.47e-8 RR interval (heart rate); LIHC cis rs929354 0.742 rs7785227 chr7:156999297 C/T cg17757837 chr7:157058334 UBE3C 0.74 12.06 0.55 3.84e-28 Body mass index; LIHC cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg17747265 chr1:1875780 NA -0.56 -10.75 -0.5 2e-23 Body mass index; LIHC cis rs2404602 0.692 rs66866130 chr15:77128574 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.87 0.3 1.04e-8 Blood metabolite levels; LIHC cis rs6466055 0.666 rs4730081 chr7:105006850 C/T cg04380332 chr7:105027541 SRPK2 -0.37 -6.9 -0.35 2.52e-11 Schizophrenia; LIHC cis rs7487075 0.930 rs4076248 chr12:46833605 C/T cg22049899 chr12:47219821 SLC38A4 0.34 5.99 0.31 5.44e-9 Itch intensity from mosquito bite; LIHC cis rs9611565 0.592 rs57102627 chr22:41987627 T/C cg03806693 chr22:41940476 POLR3H -0.84 -9.3 -0.45 1.71e-18 Vitiligo; LIHC cis rs11628318 0.515 rs8009257 chr14:103155594 A/G cg12046867 chr14:103022105 NA 0.4 6.04 0.31 4.06e-9 Platelet count; LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.11 0.55 2.44e-28 Height; LIHC cis rs13191362 1.000 rs67046187 chr6:163068532 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.77 6.74 0.34 6.68e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs763121 0.853 rs5750627 chr22:38982321 A/G cg14440974 chr22:39074834 NA -0.36 -6.04 -0.31 4.07e-9 Menopause (age at onset); LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs8180040 0.726 rs1869869 chr3:47027833 G/A cg02527881 chr3:46936655 PTH1R -0.32 -6.11 -0.31 2.69e-9 Colorectal cancer; LIHC cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg14983838 chr19:29218262 NA 0.48 7.56 0.38 3.66e-13 Methadone dose in opioid dependence; LIHC trans rs7618501 0.933 rs1128535 chr3:49866392 C/T cg21659725 chr3:3221576 CRBN 0.97 19.09 0.72 8.38e-56 Intelligence (multi-trait analysis); LIHC cis rs317689 0.876 rs547332 chr12:69743639 C/G cg14784868 chr12:69753453 YEATS4 0.7 10.55 0.5 1e-22 Response to diuretic therapy; LIHC cis rs17102423 0.755 rs4902358 chr14:65542477 A/G cg11161011 chr14:65562177 MAX -0.53 -7.44 -0.37 8.12e-13 Obesity-related traits; LIHC cis rs17685 0.784 rs1613890 chr7:75735037 T/C cg04610667 chr7:75704037 NA -0.33 -5.94 -0.31 6.93e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs870825 0.860 rs72689295 chr4:185600930 T/C cg04058563 chr4:185651563 MLF1IP 0.84 7.01 0.35 1.31e-11 Blood protein levels; LIHC cis rs1707322 0.721 rs10890346 chr1:46223892 C/T cg03146154 chr1:46216737 IPP -0.57 -9.7 -0.46 8.38e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg09222892 chr1:25734099 RHCE 0.48 9.06 0.44 1.02e-17 Erythrocyte sedimentation rate; LIHC cis rs9649465 1.000 rs2299985 chr7:123369044 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.06 -0.4 1.25e-14 Migraine; LIHC cis rs6120849 0.518 rs11696652 chr20:33637060 T/G cg24642439 chr20:33292090 TP53INP2 0.65 7.05 0.36 9.65e-12 Protein C levels; LIHC cis rs2976388 0.590 rs3736011 chr8:143817789 G/A cg06565975 chr8:143823917 SLURP1 -0.41 -7.72 -0.39 1.27e-13 Urinary tract infection frequency; LIHC cis rs6942756 0.876 rs1559486 chr7:129015894 C/T cg02491457 chr7:128862824 NA -0.58 -8.82 -0.43 5.82e-17 White matter hyperintensity burden; LIHC cis rs3857067 1.000 rs3857067 chr4:95026434 A/T cg11021082 chr4:95130006 SMARCAD1 -0.41 -7.32 -0.37 1.79e-12 QT interval; LIHC cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg13126279 chr21:47581558 C21orf56 -0.44 -7.02 -0.35 1.22e-11 Testicular germ cell tumor; LIHC cis rs11030122 0.687 rs10835521 chr11:4056004 A/T cg18678763 chr11:4115507 RRM1 -0.56 -8.57 -0.42 3.68e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs7833790 0.660 rs67666182 chr8:82772037 A/G cg17211192 chr8:82754475 SNX16 0.57 10.37 0.49 4.33e-22 Diastolic blood pressure; LIHC cis rs7512552 0.839 rs11205357 chr1:150267798 T/C cg15654264 chr1:150340011 RPRD2 -0.69 -11.8 -0.54 3.34e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs304172 0.793 rs304170 chr3:62780639 A/G cg19950079 chr6:79788502 PHIP 0.87 6.25 0.32 1.25e-9 IgG glycosylation; LIHC cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg02290350 chr8:58132656 NA 0.41 8.72 0.43 1.25e-16 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.541 rs1740741 chr10:38515334 C/T cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs11822910 0.724 rs60961847 chr11:57184224 G/A cg00522883 chr11:57194120 SLC43A3 0.72 8.48 0.42 6.95e-16 Platelet distribution width; LIHC cis rs1355223 0.902 rs10501134 chr11:34749137 T/C cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.46 -0.33 3.61e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2836950 0.565 rs8134214 chr21:40542367 A/C cg11644478 chr21:40555479 PSMG1 -0.38 -6.06 -0.31 3.65e-9 Menarche (age at onset); LIHC cis rs9902453 0.845 rs12452201 chr17:28214173 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.03e-27 Coffee consumption (cups per day); LIHC cis rs7647973 0.925 rs4384984 chr3:49289878 T/G cg07636037 chr3:49044803 WDR6 0.51 6.5 0.33 2.78e-10 Menarche (age at onset); LIHC cis rs9807989 0.524 rs6759479 chr2:103040047 A/C cg03938978 chr2:103052716 IL18RAP 0.3 5.73 0.3 2.19e-8 Asthma; LIHC cis rs614226 1.000 rs7174 chr12:121017171 A/G cg01236616 chr12:121019343 POP5 1.23 18.11 0.7 7.3e-52 Type 1 diabetes nephropathy; LIHC cis rs1789 0.903 rs4616746 chr4:15673098 A/G cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.86 -0.3 1.07e-8 Blood protein levels; LIHC cis rs11098499 0.599 rs3864142 chr4:120266191 A/T cg09307838 chr4:120376055 NA 0.63 9.84 0.47 2.82e-20 Corneal astigmatism; LIHC cis rs929354 0.772 rs1182448 chr7:157021415 G/A cg05182265 chr7:156933206 UBE3C 0.33 6.29 0.32 9.9e-10 Body mass index; LIHC cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.93 8.24 0.41 3.62e-15 Platelet count; LIHC cis rs9309473 1.000 rs13421462 chr2:73719875 A/C cg20560298 chr2:73613845 ALMS1 -0.56 -6.5 -0.33 2.87e-10 Metabolite levels; LIHC cis rs400736 0.729 rs1546846 chr1:8004259 C/T cg25007680 chr1:8021821 PARK7 -0.46 -7.29 -0.37 2.13e-12 Response to antidepressants and depression; LIHC cis rs12620999 0.941 rs10803654 chr2:238036570 C/T cg23555395 chr2:238036564 NA -0.32 -6.11 -0.31 2.71e-9 Systemic lupus erythematosus; LIHC cis rs12220238 1.000 rs11000888 chr10:75901929 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.53 0.33 2.33e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -5.93 -0.31 7.58e-9 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs1414344 chr6:8471365 C/A cg21535247 chr6:8435926 SLC35B3 0.61 8.06 0.4 1.29e-14 Motion sickness; LIHC cis rs1008375 1.000 rs1121090 chr4:17676437 C/G cg02297831 chr4:17616191 MED28 0.42 6.65 0.34 1.19e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2073300 1.000 rs6114139 chr20:23458390 T/G cg12062639 chr20:23401060 NAPB 0.78 9.87 0.47 2.16e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg09222892 chr1:25734099 RHCE -0.47 -8.77 -0.43 8.77e-17 Erythrocyte sedimentation rate; LIHC cis rs67460515 0.563 rs13085336 chr3:160880599 G/A cg03342759 chr3:160939853 NMD3 -0.62 -9.43 -0.45 6.57e-19 Parkinson's disease; LIHC cis rs7100689 0.646 rs10788562 chr10:82072310 C/T cg00277334 chr10:82204260 NA 0.59 7.44 0.37 8.05e-13 Post bronchodilator FEV1; LIHC cis rs11098499 0.863 rs36040693 chr4:120477616 A/G cg09307838 chr4:120376055 NA 0.75 11.44 0.53 6.88e-26 Corneal astigmatism; LIHC trans rs9929218 0.551 rs2274240 chr16:68725486 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.93 22.42 0.77 3.87e-69 Colorectal cancer; LIHC cis rs908922 0.676 rs4845782 chr1:152492225 A/G cg20991723 chr1:152506922 NA 0.59 10.46 0.49 2.16e-22 Hair morphology; LIHC cis rs1775715 1.000 rs1775715 chr10:32309005 A/G cg14930904 chr10:32216787 ARHGAP12 -0.41 -7.39 -0.37 1.13e-12 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs2243480 1.000 rs160644 chr7:65558186 C/T cg10756647 chr7:56101905 PSPH 1.06 13.26 0.58 1.11e-32 Diabetic kidney disease; LIHC cis rs12477438 0.539 rs12999417 chr2:99865548 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.77 -13.49 -0.59 1.53e-33 Chronic sinus infection; LIHC cis rs6066825 0.644 rs6019393 chr20:47334435 G/C cg18078177 chr20:47281410 PREX1 0.41 6.67 0.34 1.05e-10 Colorectal cancer; LIHC cis rs539514 0.627 rs9530463 chr13:76293772 C/T cg04757411 chr13:76259545 LMO7 -0.44 -7.42 -0.37 9.61e-13 Type 1 diabetes; LIHC cis rs13064411 0.735 rs10511326 chr3:113216325 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg24705708 chr2:74329833 TET3 0.5 6.22 0.32 1.47e-9 Lung function (FEV1); LIHC cis rs9916302 0.904 rs4794807 chr17:37531718 T/A cg03013999 chr17:37608204 MED1 -0.36 -5.99 -0.31 5.35e-9 Glomerular filtration rate (creatinine); LIHC cis rs4409675 0.576 rs7535816 chr1:28234054 A/G cg23691781 chr1:28212827 C1orf38 0.31 7.33 0.37 1.64e-12 Corneal astigmatism; LIHC cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg19318889 chr4:1322082 MAEA 0.47 7.39 0.37 1.17e-12 Longevity; LIHC cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg18404041 chr3:52824283 ITIH1 -0.66 -11.04 -0.51 1.86e-24 Bipolar disorder; LIHC trans rs2830585 0.700 rs73187830 chr21:28369613 G/A cg00844328 chr13:33002010 N4BP2L1 0.5 6.05 0.31 3.88e-9 Blood protein levels; LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs7552404 1.000 rs6672180 chr1:76123973 C/G cg03433033 chr1:76189801 ACADM 0.69 9.94 0.47 1.24e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs67311347 1.000 rs977652 chr3:40479169 A/G cg24209194 chr3:40518798 ZNF619 0.46 6.86 0.35 3.32e-11 Renal cell carcinoma; LIHC cis rs875971 1.000 rs10244498 chr7:66116056 A/G cg18876405 chr7:65276391 NA 0.33 6.0 0.31 5.06e-9 Aortic root size; LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.11 0.55 2.54e-28 Height; LIHC cis rs17376456 0.877 rs7701011 chr5:93311456 G/A cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs1707322 0.721 rs12045096 chr1:46114428 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg11937346 chr2:201936362 NDUFB3;FAM126B 0.33 6.15 0.32 2.11e-9 Calcium levels; LIHC cis rs2073300 0.609 rs12625164 chr20:23354269 T/C cg16736954 chr20:23401023 NAPB 0.7 8.18 0.4 5.66e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg21003380 chr1:156261207 TMEM79 0.38 6.11 0.31 2.72e-9 Tonsillectomy; LIHC cis rs3749237 0.595 rs1464568 chr3:49458266 G/A cg06212747 chr3:49208901 KLHDC8B 0.43 5.72 0.3 2.38e-8 Resting heart rate; LIHC cis rs2075371 1.000 rs1421484 chr7:133979795 T/C cg20476274 chr7:133979776 SLC35B4 0.76 13.15 0.58 2.89e-32 Mean platelet volume; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg05970768 chr5:171682616 UBTD2 0.38 6.05 0.31 3.88e-9 Alopecia areata; LIHC trans rs9929218 0.551 rs7201437 chr16:68727130 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.89 19.89 0.73 4.77e-59 Colorectal cancer; LIHC cis rs1691799 0.867 rs1039056 chr12:66760391 C/T cg16791601 chr12:66731901 HELB -0.48 -10.3 -0.49 7.81e-22 White blood cell count (basophil); LIHC cis rs892961 0.932 rs6501954 chr17:75414398 G/C cg01320579 chr17:75405842 SEPT9 0.52 7.44 0.37 8.37e-13 Airflow obstruction; LIHC cis rs36051895 0.623 rs10283473 chr9:5244708 C/A cg02405213 chr9:5042618 JAK2 -0.63 -10.06 -0.48 5.15e-21 Pediatric autoimmune diseases; LIHC cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC trans rs1005277 0.505 rs200910 chr10:38108176 C/T cg17830980 chr10:43048298 ZNF37B -0.46 -8.85 -0.43 4.64e-17 Extrinsic epigenetic age acceleration; LIHC cis rs6430585 1.000 rs6430585 chr2:136506927 A/C cg15123519 chr2:136567270 LCT 0.34 5.83 0.3 1.29e-8 Corneal structure; LIHC cis rs477692 1.000 rs513736 chr10:131406489 C/T cg19680672 chr10:131412579 MGMT -0.45 -7.07 -0.36 8.6e-12 Response to temozolomide; LIHC cis rs853679 0.517 rs1904841 chr6:28108085 C/T cg23485639 chr6:28045615 ZNF165 0.43 5.75 0.3 1.93e-8 Depression; LIHC cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg04025307 chr7:1156635 C7orf50 0.63 10.88 0.51 6.85e-24 Longevity;Endometriosis; LIHC cis rs10426930 1.000 rs10426930 chr19:5038917 G/A cg18473234 chr19:5097819 KDM4B 0.52 6.44 0.33 4.12e-10 Monocyte percentage of white cells; LIHC cis rs9868809 0.881 rs9878063 chr3:48678971 T/G cg07636037 chr3:49044803 WDR6 -0.53 -6.39 -0.33 5.39e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs473651 1.000 rs473651 chr2:239335401 A/C cg18131467 chr2:239335373 ASB1 1.05 19.8 0.73 1.11e-58 Multiple system atrophy; LIHC cis rs4727027 0.704 rs12704070 chr7:148902789 G/A cg23583168 chr7:148888333 NA -0.77 -11.86 -0.54 2.01e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs7267979 1.000 rs2257988 chr20:25270003 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs7786877 0.680 rs28584500 chr7:100216341 G/A cg00334542 chr7:100209784 MOSPD3 -0.74 -7.8 -0.39 7.63e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs4596713 0.507 rs2275428 chr9:71792582 A/T cg16512924 chr15:28394682 HERC2 0.38 6.17 0.32 1.97e-9 Headache; LIHC cis rs34375054 0.624 rs7295689 chr12:125680922 T/G cg25124228 chr12:125621409 AACS -0.44 -7.38 -0.37 1.19e-12 Post bronchodilator FEV1/FVC ratio; LIHC cis rs9457247 1.000 rs394522 chr6:167398071 A/C cg12798992 chr6:167411361 FGFR1OP 0.6 9.97 0.47 1.01e-20 Crohn's disease; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg20102877 chr2:27665638 KRTCAP3 -0.43 -6.03 -0.31 4.32e-9 Total body bone mineral density; LIHC cis rs7107174 1.000 rs10793304 chr11:78064907 A/G cg02023728 chr11:77925099 USP35 0.42 8.16 0.4 6.39e-15 Testicular germ cell tumor; LIHC cis rs2153535 0.542 rs6905925 chr6:8440030 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs6500602 0.701 rs6500614 chr16:4573938 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.56 8.42 0.41 1.09e-15 Schizophrenia; LIHC cis rs10464366 0.517 rs13231075 chr7:39174806 G/T cg15212455 chr7:39170539 POU6F2 0.47 8.45 0.42 8.36e-16 IgG glycosylation; LIHC cis rs2292096 1.000 rs2275194 chr1:200821924 C/T cg11814564 chr1:200748674 CAMSAP1L1 -0.44 -5.97 -0.31 5.88e-9 Epilepsy; LIHC cis rs7618501 0.722 rs9853458 chr3:49783211 A/C cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs1448094 0.512 rs7957170 chr12:86243282 A/G cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs6701037 0.875 rs1057301 chr1:175126524 T/C cg00321850 chr1:175162397 KIAA0040 -0.38 -5.86 -0.3 1.08e-8 Alcohol dependence; LIHC cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.76 0.47 5.24e-20 Intelligence (multi-trait analysis); LIHC cis rs8044868 0.530 rs2288002 chr16:72057282 A/G cg01557791 chr16:72042693 DHODH -0.4 -6.71 -0.34 7.93e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs7789940 1.000 rs758944 chr7:75953297 G/T cg10167463 chr7:75959203 YWHAG -0.44 -7.03 -0.36 1.11e-11 Multiple sclerosis; LIHC cis rs7520050 0.966 rs6677007 chr1:46400590 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.0 0.31 5.05e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 8.8 0.43 7.08e-17 Platelet count; LIHC cis rs7666738 0.830 rs10001701 chr4:98918871 G/C cg05340658 chr4:99064831 C4orf37 0.64 11.67 0.53 1.06e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs736408 0.677 rs678 chr3:52820981 A/T cg18404041 chr3:52824283 ITIH1 -0.64 -10.46 -0.49 2.12e-22 Bipolar disorder; LIHC cis rs12477438 0.798 rs2309524 chr2:99659510 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.67 -0.53 1.06e-26 Chronic sinus infection; LIHC cis rs1823913 0.599 rs13001899 chr2:192150168 C/T cg12404831 chr2:192114017 MYO1B 0.28 5.72 0.3 2.39e-8 Obesity-related traits; LIHC cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg06481639 chr22:41940642 POLR3H -0.69 -7.0 -0.35 1.39e-11 Vitiligo; LIHC cis rs903552 0.736 rs11858491 chr15:102007456 C/T cg00659931 chr15:102010125 PCSK6 0.5 6.97 0.35 1.63e-11 Diabetic kidney disease; LIHC cis rs7618501 1.000 rs9859153 chr3:49807085 G/T cg21467203 chr3:49911342 NA -0.41 -7.07 -0.36 9e-12 Intelligence (multi-trait analysis); LIHC cis rs80282103 0.571 rs10047269 chr10:1103058 G/A cg08668510 chr10:1095578 IDI1 0.71 7.12 0.36 6.24e-12 Glomerular filtration rate (creatinine); LIHC trans rs2832191 0.647 rs11170 chr21:30378090 C/T cg14791747 chr16:20752902 THUMPD1 -0.46 -6.42 -0.33 4.49e-10 Dental caries; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21887597 chr15:83419354 NA 0.44 6.37 0.33 6.09e-10 Pancreatic cancer; LIHC cis rs8062405 0.720 rs9926245 chr16:28555706 T/A cg07451762 chr16:28383216 NA 0.33 6.74 0.34 6.7e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs929354 0.772 rs3802120 chr7:156977794 C/T cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs992157 0.710 rs12612347 chr2:219057338 C/T cg00012203 chr2:219082015 ARPC2 -0.92 -16.4 -0.66 5.47e-45 Colorectal cancer; LIHC cis rs11048434 0.666 rs12371786 chr12:9090086 G/A cg04155231 chr12:9217510 LOC144571 0.32 6.11 0.31 2.75e-9 Sjögren's syndrome; LIHC cis rs13191362 0.935 rs7769048 chr6:163010040 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg22974920 chr21:40686053 BRWD1 -0.41 -6.0 -0.31 5.02e-9 Cognitive function; LIHC cis rs10256972 0.900 rs7812072 chr7:1053862 A/G cg04025307 chr7:1156635 C7orf50 0.5 8.34 0.41 1.82e-15 Longevity;Endometriosis; LIHC cis rs6912958 0.781 rs6454631 chr6:88225863 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.99 -0.4 2.05e-14 Monocyte percentage of white cells; LIHC cis rs593982 1.000 rs470360 chr11:65500530 T/C cg08755490 chr11:65554678 OVOL1 0.55 8.56 0.42 3.82e-16 Atopic dermatitis; LIHC cis rs6912958 0.559 rs369674 chr6:88043402 C/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.39 -7.89 -0.39 4.18e-14 Monocyte percentage of white cells; LIHC trans rs2749592 0.531 rs1208559 chr10:38221370 T/C cg17830980 chr10:43048298 ZNF37B 0.46 9.18 0.44 4.31e-18 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6684514 1.000 rs6679145 chr1:156256000 T/C cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs6754311 0.513 rs1438304 chr2:136503157 A/G cg07169764 chr2:136633963 MCM6 -0.68 -9.91 -0.47 1.68e-20 Mosquito bite size; LIHC cis rs9611565 0.512 rs4822052 chr22:42193741 G/A cg06634786 chr22:41940651 POLR3H -0.61 -6.6 -0.34 1.58e-10 Vitiligo; LIHC cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg05590025 chr7:65112418 INTS4L2 -0.66 -7.2 -0.36 3.94e-12 Diabetic kidney disease; LIHC cis rs13336428 0.730 rs3946124 chr16:1525779 A/G cg08008072 chr16:1524255 CLCN7 0.62 11.86 0.54 2e-27 Bone mineral density; LIHC cis rs4407350 0.837 rs4823328 chr22:44908999 C/T cg26276947 chr22:44892394 LDOC1L 0.34 6.56 0.33 1.99e-10 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.3 -0.68 1.29e-48 Gut microbiome composition (summer); LIHC cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg08888203 chr3:10149979 C3orf24 0.64 7.22 0.36 3.36e-12 Alzheimer's disease; LIHC trans rs3780486 0.846 rs10813954 chr9:33137596 A/C cg04842962 chr6:43655489 MRPS18A 1.08 25.4 0.81 1.05e-80 IgG glycosylation; LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg20570016 chr1:156261298 TMEM79 0.37 6.01 0.31 4.75e-9 Tonsillectomy; LIHC cis rs2412488 0.888 rs6554104 chr4:54276662 A/T cg22241045 chr4:54363911 LNX1 -0.41 -6.71 -0.34 8.15e-11 DNA methylation (variation); LIHC cis rs875971 0.638 rs801216 chr7:66011667 T/C cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs5769765 0.955 rs9616204 chr22:50303530 T/C cg02269571 chr22:50332266 NA -0.74 -9.76 -0.47 5.22e-20 Schizophrenia; LIHC cis rs4665809 1.000 rs1030730 chr2:26284143 T/C cg04944784 chr2:26401820 FAM59B -0.68 -8.47 -0.42 7.14e-16 Gut microbiome composition (summer); LIHC cis rs12997796 0.556 rs12477737 chr2:86930966 G/T cg25203885 chr2:87302643 LOC285074 -0.63 -5.99 -0.31 5.24e-9 Schizophrenia; LIHC cis rs11719291 0.833 rs13074318 chr3:48816725 C/T cg07636037 chr3:49044803 WDR6 -0.87 -7.21 -0.36 3.61e-12 Cognitive function; LIHC cis rs9303401 0.659 rs2072316 chr17:56604813 G/T cg25039879 chr17:56429692 SUPT4H1 0.74 8.28 0.41 2.76e-15 Cognitive test performance; LIHC cis rs2066819 1.000 rs2066818 chr12:56753822 C/A cg26714650 chr12:56694279 CS -1.35 -12.74 -0.57 1.09e-30 Psoriasis vulgaris; LIHC cis rs9733 0.650 rs1971378 chr1:150597261 C/T cg18016565 chr1:150552671 MCL1 -0.54 -10.98 -0.51 3.13e-24 Tonsillectomy; LIHC cis rs858239 0.600 rs13438188 chr7:23144197 C/T cg23682824 chr7:23144976 KLHL7 -0.42 -6.29 -0.32 9.43e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg27094323 chr7:1216898 NA -0.4 -5.78 -0.3 1.7e-8 Longevity;Endometriosis; LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg02782426 chr3:40428986 ENTPD3 0.33 6.0 0.31 4.91e-9 Renal cell carcinoma; LIHC cis rs3015497 0.789 rs2934688 chr14:51112360 G/A cg09863266 chr14:51125203 SAV1 -0.44 -7.06 -0.36 9.54e-12 Mean platelet volume; LIHC cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.02 -0.35 1.22e-11 Diabetic kidney disease; LIHC cis rs561341 1.000 rs527256 chr17:30321293 C/G cg00745463 chr17:30367425 LRRC37B -0.77 -5.73 -0.3 2.16e-8 Hip circumference adjusted for BMI; LIHC cis rs780096 0.546 rs1104 chr2:27599875 T/G cg21747090 chr2:27597821 SNX17 -0.46 -6.99 -0.35 1.4e-11 Total body bone mineral density; LIHC cis rs1799949 1.000 rs4793229 chr17:41418334 C/T cg25072359 chr17:41440525 NA -0.38 -6.13 -0.31 2.49e-9 Menopause (age at onset); LIHC cis rs2066819 1.000 rs2066808 chr12:56737973 A/G cg26714650 chr12:56694279 CS -1.25 -15.27 -0.64 1.6e-40 Psoriasis vulgaris; LIHC cis rs1816752 0.905 rs7991450 chr13:25000036 T/G cg02811702 chr13:24901961 NA 0.24 5.99 0.31 5.26e-9 Obesity-related traits; LIHC cis rs6430585 0.583 rs3769013 chr2:136556182 C/T cg07169764 chr2:136633963 MCM6 1.25 19.61 0.73 6.4e-58 Corneal structure; LIHC cis rs8078723 1.000 rs4794823 chr17:38166265 A/T cg17467752 chr17:38218738 THRA 0.76 13.99 0.6 1.82e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2257205 0.667 rs8076021 chr17:56694646 T/G cg12560992 chr17:57184187 TRIM37 0.71 7.86 0.39 5.22e-14 Pancreatic cancer; LIHC cis rs1865760 0.713 rs6928951 chr6:25995554 C/T cg18357526 chr6:26021779 HIST1H4A 0.42 6.27 0.32 1.07e-9 Height; LIHC cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg18404041 chr3:52824283 ITIH1 -0.47 -7.79 -0.39 8.2e-14 Electroencephalogram traits; LIHC cis rs6547741 1.000 rs6749052 chr2:27772879 A/T cg27432699 chr2:27873401 GPN1 0.71 11.37 0.52 1.21e-25 Oral cavity cancer; LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs9902453 0.904 rs4567782 chr17:28268800 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.97 0.6 2.11e-35 Coffee consumption (cups per day); LIHC cis rs1997103 0.954 rs2177809 chr7:55378125 T/C cg17469321 chr7:55412551 NA 0.49 7.15 0.36 5.38e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg26874164 chr19:58962979 ZNF324B 0.58 8.87 0.43 4.06e-17 Uric acid clearance; LIHC cis rs8053891 0.664 rs34972708 chr16:72008225 A/G cg01557791 chr16:72042693 DHODH -0.51 -7.44 -0.37 8.46e-13 Coronary artery disease; LIHC cis rs13191362 0.935 rs67337490 chr6:162953961 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.76 0.3 1.92e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs72781680 1.000 rs56339200 chr2:24188194 C/A cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs9715521 0.775 rs11723682 chr4:59851969 C/T cg11281224 chr4:60001000 NA -0.31 -5.71 -0.3 2.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7917772 0.503 rs7087665 chr10:104282418 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.96 0.57 1.63e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1707322 1.000 rs4660331 chr1:46458783 A/C cg03146154 chr1:46216737 IPP 0.47 7.63 0.38 2.32e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg13395646 chr4:1353034 KIAA1530 -0.38 -5.73 -0.3 2.18e-8 Longevity; LIHC cis rs6089829 0.888 rs4809471 chr20:61684287 G/A cg08564027 chr20:61660810 NA 0.37 6.71 0.34 8.08e-11 Prostate cancer (SNP x SNP interaction); LIHC cis rs4780401 0.609 rs8055247 chr16:11827543 G/A cg01061890 chr16:11836724 TXNDC11 -0.66 -10.51 -0.49 1.41e-22 Rheumatoid arthritis; LIHC cis rs400736 0.729 rs2493216 chr1:8008366 C/A cg25007680 chr1:8021821 PARK7 -0.47 -7.34 -0.37 1.53e-12 Response to antidepressants and depression; LIHC cis rs703842 0.964 rs2014886 chr12:58177437 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.87 14.3 0.61 1.07e-36 Multiple sclerosis; LIHC cis rs116095464 0.558 rs59113266 chr5:279965 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs4409675 0.576 rs10794507 chr1:28216072 T/C cg23691781 chr1:28212827 C1orf38 0.32 7.68 0.38 1.65e-13 Corneal astigmatism; LIHC cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg05025164 chr4:1340916 KIAA1530 0.42 6.46 0.33 3.51e-10 Obesity-related traits; LIHC cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg06634786 chr22:41940651 POLR3H -0.73 -7.97 -0.4 2.4e-14 Vitiligo; LIHC cis rs1448094 0.512 rs7302741 chr12:86237127 C/T cg02569458 chr12:86230093 RASSF9 0.5 6.57 0.33 1.88e-10 Major depressive disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09809285 chr5:188949 PLEKHG4B 0.45 6.04 0.31 3.92e-9 Lung function (FEV1/FVC); LIHC cis rs734999 0.967 rs6671426 chr1:2504234 C/A cg18854424 chr1:2615690 NA 0.33 6.94 0.35 1.97e-11 Ulcerative colitis; LIHC cis rs12220238 1.000 rs12355771 chr10:75894404 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.74 7.04 0.36 1.04e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs875971 0.964 rs12668936 chr7:65914404 C/T cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg11062466 chr8:58055876 NA -0.46 -6.56 -0.33 1.94e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03228054 chr9:19049082 RRAGA 0.44 6.59 0.34 1.62e-10 Cognitive function; LIHC cis rs6977660 1.000 rs13231036 chr7:19806141 G/A cg07541023 chr7:19748670 TWISTNB 0.39 6.16 0.32 2.01e-9 Thyroid stimulating hormone; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg09872104 chr7:134855509 C7orf49 -0.41 -6.17 -0.32 1.89e-9 Immature fraction of reticulocytes; LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg11965913 chr1:205819406 PM20D1 0.63 9.18 0.44 4.2e-18 Menarche (age at onset); LIHC cis rs4141404 0.701 rs5753483 chr22:31549581 A/G cg07713946 chr22:31675144 LIMK2 -0.34 -5.79 -0.3 1.58e-8 Paclitaxel-induced neuropathy; LIHC cis rs1789 0.786 rs6414768 chr4:15695363 A/G cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.77 -0.3 1.75e-8 Blood protein levels; LIHC cis rs12477438 0.520 rs1453563 chr2:99720267 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.16e-21 Chronic sinus infection; LIHC cis rs7582720 1.000 rs7605484 chr2:203724495 T/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 5.95 0.31 6.55e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7633770 0.841 rs11709020 chr3:46680063 A/G cg11219411 chr3:46661640 NA -0.53 -9.44 -0.45 6.06e-19 Coronary artery disease; LIHC cis rs9649213 0.593 rs6465664 chr7:97921834 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.79 -0.3 1.61e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs1712517 0.873 rs1891292 chr10:105001510 A/G cg05636881 chr10:105038444 INA -0.4 -6.43 -0.33 4.41e-10 Migraine; LIHC cis rs6912958 0.678 rs9450733 chr6:88250081 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.07 -0.4 1.2e-14 Monocyte percentage of white cells; LIHC cis rs10256972 0.758 rs9801444 chr7:1080444 A/C cg07308232 chr7:1071921 C7orf50 0.55 8.59 0.42 3.08e-16 Longevity;Endometriosis; LIHC cis rs853679 0.517 rs9295759 chr6:28124469 C/T cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg03806693 chr22:41940476 POLR3H 0.97 10.43 0.49 2.59e-22 Vitiligo; LIHC cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs546131 0.642 rs10836315 chr11:34853346 C/T cg11058730 chr11:34937778 PDHX;APIP 0.53 6.45 0.33 3.83e-10 Lung disease severity in cystic fibrosis; LIHC cis rs4713118 0.869 rs9348775 chr6:27695329 C/T cg20933634 chr6:27740509 NA 0.46 6.16 0.32 2.07e-9 Parkinson's disease; LIHC cis rs7937890 1.000 rs2970334 chr11:14329355 C/T cg02886208 chr11:14281011 SPON1 0.58 8.52 0.42 5.24e-16 Mitochondrial DNA levels; LIHC cis rs798554 0.836 rs2260230 chr7:2822986 T/A cg19346786 chr7:2764209 NA -0.46 -6.95 -0.35 1.9e-11 Height; LIHC cis rs477692 0.967 rs519690 chr10:131424033 G/A cg19680672 chr10:131412579 MGMT -0.45 -6.86 -0.35 3.33e-11 Response to temozolomide; LIHC cis rs11673344 0.704 rs551717 chr19:37427879 A/G cg27390819 chr19:37464633 NA -0.5 -6.01 -0.31 4.88e-9 Obesity-related traits; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg00280220 chr17:61926910 NA 0.39 6.16 0.32 2.01e-9 Prudent dietary pattern; LIHC cis rs8017423 0.608 rs12588149 chr14:90822676 G/A cg04374321 chr14:90722782 PSMC1 -0.46 -6.66 -0.34 1.07e-10 Mortality in heart failure; LIHC cis rs6088580 0.609 rs2378205 chr20:33110803 C/G cg08999081 chr20:33150536 PIGU 0.67 13.46 0.59 1.89e-33 Glomerular filtration rate (creatinine); LIHC cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg15691649 chr6:25882328 NA -0.56 -7.12 -0.36 6.42e-12 Intelligence (multi-trait analysis); LIHC cis rs8084351 0.599 rs4940242 chr18:50687196 G/A cg24270629 chr18:50823537 DCC -0.44 -6.57 -0.33 1.82e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs4423214 0.840 rs3794057 chr11:71186744 G/A cg05163923 chr11:71159392 DHCR7 -0.6 -7.9 -0.39 3.79e-14 Vitamin D levels; LIHC cis rs1419980 0.730 rs57677315 chr12:7746232 C/T cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs2279817 0.863 rs12753636 chr1:18013602 G/A cg21791023 chr1:18019539 ARHGEF10L -0.69 -8.38 -0.41 1.42e-15 Neuroticism; LIHC cis rs2439831 0.850 rs12441861 chr15:44060883 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.55 0.42 4.29e-16 Lung cancer in ever smokers; LIHC trans rs1814175 0.676 rs11040647 chr11:49935947 A/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs769267 1.000 rs2301669 chr19:19453560 C/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -9.87 -0.47 2.26e-20 Tonsillectomy; LIHC cis rs72627123 0.737 rs61475846 chr14:74485781 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.68 0.46 9.74e-20 Morning vs. evening chronotype; LIHC cis rs3617 0.573 rs4687682 chr3:52916939 T/C cg11645453 chr3:52864694 ITIH4 -0.23 -6.22 -0.32 1.46e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs2073499 1.000 rs739431 chr3:50255305 A/G cg03645007 chr3:50255295 SLC38A3 0.45 6.75 0.34 6.35e-11 Schizophrenia; LIHC cis rs4865169 0.560 rs1277311 chr4:57902761 C/T cg25525207 chr4:57843836 C4orf14;POLR2B -0.38 -5.84 -0.3 1.23e-8 Breast cancer; LIHC cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg21724239 chr8:58056113 NA 0.59 7.14 0.36 5.69e-12 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26148815 chr2:113379707 NA 0.37 6.13 0.31 2.46e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs9470366 1.000 rs9470366 chr6:36625562 C/T cg08179530 chr6:36648295 CDKN1A 0.53 6.49 0.33 3.04e-10 QRS duration; LIHC cis rs4631830 0.683 rs10763193 chr10:51504938 G/A cg16070123 chr10:51489643 NA 0.38 6.03 0.31 4.15e-9 Prostate-specific antigen levels; LIHC cis rs910316 0.663 rs175034 chr14:75463687 T/G cg08847533 chr14:75593920 NEK9 -0.86 -17.21 -0.68 2.94e-48 Height; LIHC cis rs7296418 0.518 rs28825193 chr12:123878262 T/C cg00376283 chr12:123451042 ABCB9 0.62 10.24 0.48 1.25e-21 Platelet count; LIHC trans rs66887589 0.967 rs56173225 chr4:120509972 G/A cg25214090 chr10:38739885 LOC399744 -0.39 -6.37 -0.33 6.04e-10 Diastolic blood pressure; LIHC cis rs4820294 1.000 rs713835 chr22:38064650 C/T cg00142150 chr22:38071001 LGALS1 0.7 11.49 0.53 4.61e-26 Fat distribution (HIV); LIHC cis rs1215050 0.740 rs11097580 chr4:98767255 C/A cg05340658 chr4:99064831 C4orf37 0.4 5.88 0.3 9.88e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs8067545 0.611 rs2703814 chr17:20117151 T/C cg13482628 chr17:19912719 NA -0.42 -6.9 -0.35 2.58e-11 Schizophrenia; LIHC cis rs2991971 1.000 rs606542 chr1:46013933 T/C cg24296786 chr1:45957014 TESK2 0.5 7.18 0.36 4.44e-12 High light scatter reticulocyte count; LIHC cis rs929354 0.713 rs3802130 chr7:156965237 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs8114671 0.773 rs3746438 chr20:33584289 C/T cg07148914 chr20:33460835 GGT7 -0.58 -8.75 -0.43 9.77e-17 Height; LIHC cis rs6722750 0.846 rs34923691 chr2:64395183 C/T cg22352474 chr2:64371530 PELI1 0.46 6.67 0.34 1.04e-10 Neuroticism; LIHC cis rs10792665 0.545 rs7925212 chr11:82561984 G/A cg24227371 chr11:82718527 RAB30 -0.27 -6.45 -0.33 3.83e-10 Obesity-related traits; LIHC cis rs875971 0.830 rs6950137 chr7:65976610 G/A cg18252515 chr7:66147081 NA -0.44 -6.3 -0.32 9.3e-10 Aortic root size; LIHC cis rs644799 1.000 rs586238 chr11:95560371 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11969893 0.649 rs12527901 chr6:101280435 G/A cg12253828 chr6:101329408 ASCC3 0.93 11.93 0.54 1.1e-27 Economic and political preferences (immigration/crime); LIHC cis rs7224737 0.956 rs8081327 chr17:40274200 G/A cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs1577917 0.771 rs2842608 chr6:86295858 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.87 -0.54 1.91e-27 Response to antipsychotic treatment; LIHC cis rs7772486 0.727 rs6941429 chr6:145952283 G/A cg13319975 chr6:146136371 FBXO30 -0.4 -6.67 -0.34 1.04e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1914816 0.941 rs2460151 chr15:76487507 G/C cg03037974 chr15:76606532 NA -0.6 -6.17 -0.32 1.88e-9 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg06238570 chr21:40685208 BRWD1 0.56 6.79 0.34 4.99e-11 Cognitive function; LIHC cis rs1395 0.744 rs11126934 chr2:27476613 T/C cg23587288 chr2:27483067 SLC30A3 -0.35 -6.64 -0.34 1.21e-10 Blood metabolite levels; LIHC cis rs7107174 0.786 rs4945269 chr11:78047077 A/G cg02023728 chr11:77925099 USP35 0.43 8.38 0.41 1.38e-15 Testicular germ cell tumor; LIHC cis rs4407350 1.000 rs12169248 chr22:44920999 G/A cg11695653 chr22:44894386 LDOC1L -0.37 -6.11 -0.31 2.64e-9 Intelligence (multi-trait analysis); LIHC cis rs4423214 0.879 rs12803256 chr11:71132868 A/G cg05163923 chr11:71159392 DHCR7 0.95 15.28 0.64 1.47e-40 Vitamin D levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18145393 chr4:520203 PIGG 0.42 6.18 0.32 1.85e-9 Longevity; LIHC trans rs7395555 1.000 rs34116051 chr11:80061735 G/A cg06295071 chr21:33766731 URB1 -0.43 -6.29 -0.32 9.51e-10 Response to antipsychotic treatment; LIHC cis rs936229 0.749 rs6495127 chr15:75194490 C/T cg14664628 chr15:75095509 CSK -0.72 -9.56 -0.46 2.37e-19 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs2257205 0.667 rs16943186 chr17:56801848 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -6.67 -0.34 1e-10 Pancreatic cancer; LIHC cis rs9534288 0.699 rs9534320 chr13:46665572 A/G cg15192986 chr13:46630673 CPB2 -0.42 -6.02 -0.31 4.4e-9 Blood protein levels; LIHC cis rs7843479 0.965 rs11775479 chr8:21859991 C/T cg17168535 chr8:21777572 XPO7 0.38 6.19 0.32 1.73e-9 Mean corpuscular volume; LIHC cis rs9318086 0.673 rs7981928 chr13:24435180 T/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.57 11.24 0.52 3.74e-25 Myopia (pathological); LIHC cis rs249954 0.512 rs703767 chr16:23661639 G/C cg09867953 chr16:23706666 ERN2 0.37 6.38 0.33 5.74e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1144333 0.579 rs35591768 chr1:76308257 C/T cg22875332 chr1:76189707 ACADM 0.38 6.34 0.32 7.3e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs11792861 0.926 rs7855282 chr9:111802614 T/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.53 0.42 4.71e-16 Menarche (age at onset); LIHC cis rs6449957 0.639 rs40419 chr5:67515602 T/C cg23036683 chr5:67512108 NA 0.52 7.67 0.38 1.82e-13 Cleft lip with or without cleft palate; LIHC cis rs1801251 0.778 rs2592116 chr2:233735709 G/A cg25237894 chr2:233734115 C2orf82 -0.59 -11.92 -0.54 1.29e-27 Coronary artery disease; LIHC cis rs4906332 0.868 rs4900578 chr14:103926010 A/T cg04998671 chr14:104000505 TRMT61A -0.45 -6.18 -0.32 1.86e-9 Coronary artery disease; LIHC cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg20295408 chr7:1910781 MAD1L1 -0.51 -7.51 -0.38 5.22e-13 Bipolar disorder and schizophrenia; LIHC trans rs61931739 0.500 rs11524949 chr12:34435551 C/T cg26384229 chr12:38710491 ALG10B 0.77 9.51 0.46 3.53e-19 Morning vs. evening chronotype; LIHC cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg11890956 chr21:40555474 PSMG1 -0.57 -9.5 -0.46 3.65e-19 Cognitive function; LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg14671364 chr1:107599128 PRMT6 -0.51 -7.53 -0.38 4.59e-13 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs249954 0.512 rs26767 chr16:23698457 A/C cg05131483 chr16:23706242 ERN2 0.37 6.15 0.32 2.16e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8103278 1.000 rs7256192 chr19:46338492 G/A cg11657440 chr19:46296263 DMWD -0.52 -8.09 -0.4 1.04e-14 Coronary artery disease; LIHC cis rs1552244 0.882 rs66559400 chr3:10012551 G/A cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs6088813 1.000 rs6141549 chr20:33974051 T/C cg14752227 chr20:34000481 UQCC -0.41 -5.83 -0.3 1.25e-8 Height; LIHC cis rs4727027 0.933 rs34578816 chr7:148847606 G/A cg23583168 chr7:148888333 NA -0.74 -10.58 -0.5 8.06e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs425535 0.619 rs1435521 chr4:74807928 A/G cg02530824 chr4:74847766 PF4 -0.38 -5.88 -0.3 9.94e-9 Blood protein levels; LIHC cis rs10791097 0.739 rs4936120 chr11:130723452 G/A cg12179176 chr11:130786555 SNX19 0.75 11.9 0.54 1.51e-27 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 11.46 0.53 5.76e-26 Platelet count; LIHC cis rs10870270 1.000 rs4880246 chr10:133764064 C/T cg08754478 chr10:133766260 PPP2R2D -0.54 -7.99 -0.4 2.05e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.04 0.4 1.46e-14 Height; LIHC cis rs933688 1.000 rs11959525 chr5:90703840 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.67 0.67 4.38e-46 Smoking behavior; LIHC cis rs2075371 0.863 rs34231360 chr7:133944988 A/C cg20476274 chr7:133979776 SLC35B4 0.68 9.37 0.45 9.82e-19 Mean platelet volume; LIHC cis rs644799 0.544 rs498553 chr11:95534441 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.64 9.27 0.45 2.09e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1577917 0.958 rs1335442 chr6:86466692 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.53 -0.38 4.51e-13 Response to antipsychotic treatment; LIHC cis rs8072100 0.967 rs12452315 chr17:45479446 G/T cg08085267 chr17:45401833 C17orf57 0.58 8.94 0.44 2.52e-17 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2760061 0.626 rs596208 chr1:228117982 G/C cg01200585 chr1:228362443 C1orf69 -0.4 -5.85 -0.3 1.16e-8 Diastolic blood pressure; LIHC cis rs1707322 0.656 rs2991981 chr1:46057144 A/G cg24296786 chr1:45957014 TESK2 0.4 5.73 0.3 2.23e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs950776 0.684 rs692780 chr15:78876505 C/G cg06917634 chr15:78832804 PSMA4 -0.68 -9.17 -0.44 4.4e-18 Sudden cardiac arrest; LIHC cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.73 0.34 7.2e-11 Bipolar disorder; LIHC cis rs7296418 0.922 rs12425009 chr12:123502044 C/T cg05973401 chr12:123451056 ABCB9 0.52 8.25 0.41 3.51e-15 Platelet count; LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg10096929 chr1:156261403 TMEM79 0.41 6.83 0.35 3.92e-11 Tonsillectomy; LIHC cis rs332507 0.830 rs11715641 chr3:124423675 G/A cg05980111 chr3:124395277 KALRN 0.42 6.44 0.33 3.95e-10 Plateletcrit; LIHC cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.776 rs1073522 chr21:45009219 T/A cg01579765 chr21:45077557 HSF2BP -0.36 -6.77 -0.34 5.52e-11 Mean corpuscular volume; LIHC cis rs894734 0.535 rs2366144 chr12:54324069 G/T cg17708016 chr12:54321992 NA 0.4 7.1 0.36 7.47e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC trans rs2665103 0.715 rs16973457 chr15:82563991 C/T cg18393722 chr15:85113863 UBE2QP1 -0.46 -7.28 -0.37 2.33e-12 Intelligence (multi-trait analysis); LIHC cis rs12893668 0.703 rs2274267 chr14:104029449 G/A cg19000871 chr14:103996768 TRMT61A -0.42 -6.93 -0.35 2.1e-11 Reticulocyte count; LIHC cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.44 -7.93 -0.39 3.13e-14 Prudent dietary pattern; LIHC cis rs2066819 1.000 rs116849218 chr12:56683975 C/T cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg10295955 chr4:187884368 NA 0.97 22.67 0.77 4.25e-70 Lobe attachment (rater-scored or self-reported); LIHC cis rs8060686 0.641 rs79577483 chr16:68036939 A/G cg09835421 chr16:68378352 PRMT7 -0.48 -5.82 -0.3 1.36e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs7589728 0.748 rs3791357 chr2:88478664 C/T cg14558114 chr2:88469736 THNSL2 0.59 5.79 0.3 1.64e-8 Plasma clusterin levels; LIHC cis rs9300255 0.602 rs2695479 chr12:123689386 T/C cg00376283 chr12:123451042 ABCB9 0.58 5.74 0.3 2.04e-8 Neutrophil percentage of white cells; LIHC cis rs858239 0.601 rs6461702 chr7:23249273 C/G cg18081818 chr7:23246105 NA -0.41 -5.97 -0.31 5.96e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs3741404 0.791 rs11603192 chr11:63927695 A/G cg04317338 chr11:64019027 PLCB3 0.49 6.71 0.34 8.3e-11 Platelet count; LIHC cis rs17331151 0.573 rs79664140 chr3:52866936 A/G cg04865290 chr3:52927548 TMEM110 -0.44 -6.51 -0.33 2.61e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2073300 1.000 rs2207988 chr20:23446000 C/A cg12062639 chr20:23401060 NAPB 0.83 9.78 0.47 4.3e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg10360323 chr17:41437877 NA 0.39 5.79 0.3 1.55e-8 Menopause (age at onset); LIHC cis rs7223966 1.000 rs9903903 chr17:61762044 A/G cg05941027 chr17:61774174 LIMD2 0.3 5.97 0.31 5.91e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2153535 0.580 rs1034272 chr6:8469335 G/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs3008870 0.755 rs1925409 chr1:67365089 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.64 -10.67 -0.5 3.86e-23 Lymphocyte percentage of white cells; LIHC cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg11890956 chr21:40555474 PSMG1 -0.5 -8.17 -0.4 5.97e-15 Cognitive function; LIHC cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg02359409 chr6:42947317 PEX6 -0.48 -6.79 -0.34 4.85e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6088580 0.634 rs1205345 chr20:32914699 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.13 -0.58 3.68e-32 Glomerular filtration rate (creatinine); LIHC cis rs7618501 1.000 rs7649348 chr3:49772375 G/A cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs9473924 0.505 rs7746581 chr6:50853479 T/C cg14470998 chr6:50812995 TFAP2B 0.95 10.98 0.51 3.11e-24 Body mass index; LIHC cis rs861020 0.771 rs654470 chr1:210014093 A/T cg09163369 chr1:210001066 C1orf107 0.51 6.59 0.34 1.63e-10 Orofacial clefts; LIHC cis rs1577917 0.629 rs6927475 chr6:86206773 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.34 6.13 0.31 2.48e-9 Response to antipsychotic treatment; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08137080 chr1:16482430 EPHA2 -0.45 -6.04 -0.31 4.13e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC trans rs11722228 0.549 rs73212828 chr4:10078756 C/T cg26043149 chr18:55253948 FECH 0.94 13.54 0.59 1.01e-33 Gout;Urate levels;Serum uric acid levels; LIHC cis rs8072100 0.846 rs4264433 chr17:45737275 A/T cg15066416 chr17:45501628 LOC100272146;C17orf57 0.35 5.76 0.3 1.89e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs11662586 0.517 rs7228070 chr18:77698967 C/T cg20368463 chr18:77673604 PQLC1 0.61 11.63 0.53 1.39e-26 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs918629 0.761 rs57243277 chr5:95288165 G/A cg10483112 chr5:95245456 ELL2 -0.37 -6.22 -0.32 1.42e-9 IgG glycosylation; LIHC cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg23806715 chr17:73775811 H3F3B 0.53 7.26 0.37 2.62e-12 Psoriasis; LIHC cis rs2412459 0.831 rs6492924 chr15:40272391 G/A cg01081584 chr15:40268610 EIF2AK4 -0.61 -8.35 -0.41 1.68e-15 Response to haloperidol in psychosis; LIHC cis rs10540 0.908 rs1044707 chr11:491334 G/T cg03576123 chr11:487126 PTDSS2 1.06 8.42 0.41 1.06e-15 Body mass index; LIHC cis rs4819052 0.851 rs2838848 chr21:46671017 A/G cg11663144 chr21:46675770 NA -0.32 -5.95 -0.31 6.7e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg11766577 chr21:47581405 C21orf56 0.43 7.15 0.36 5.39e-12 Testicular germ cell tumor; LIHC cis rs1707322 0.721 rs11211149 chr1:46112218 T/C cg03146154 chr1:46216737 IPP 0.57 9.74 0.47 5.94e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2727020 0.636 rs11040368 chr11:49453602 C/A cg03929089 chr4:120376271 NA -0.84 -15.97 -0.65 2.85e-43 Coronary artery disease; LIHC cis rs10751667 0.666 rs7124480 chr11:971601 G/A cg10932868 chr11:921992 NA 0.4 7.69 0.38 1.55e-13 Alzheimer's disease (late onset); LIHC cis rs12711979 0.509 rs10205540 chr2:3827839 A/G cg17052675 chr2:3827356 NA -0.72 -16.2 -0.66 3.33e-44 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs7523273 0.568 rs61821293 chr1:208007277 T/G cg22525895 chr1:207977042 MIR29B2 -0.58 -6.48 -0.33 3.23e-10 Schizophrenia; LIHC cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg07636037 chr3:49044803 WDR6 0.87 14.96 0.63 2.78e-39 Parkinson's disease; LIHC cis rs7296418 0.961 rs10848428 chr12:123572495 C/T cg00376283 chr12:123451042 ABCB9 0.74 13.0 0.58 1.15e-31 Platelet count; LIHC cis rs4900538 0.927 rs1190544 chr14:102903398 G/A cg18135206 chr14:102964638 TECPR2 -0.93 -15.76 -0.65 1.87e-42 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs34779708 0.733 rs12243593 chr10:35549045 C/T cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg00149659 chr3:10157352 C3orf10 0.7 7.21 0.36 3.69e-12 Alzheimer's disease; LIHC cis rs798554 0.660 rs2644274 chr7:2854380 A/T cg13628971 chr7:2884303 GNA12 0.42 6.57 0.33 1.93e-10 Height; LIHC cis rs1775715 0.675 rs2808085 chr10:32148599 C/T cg14930904 chr10:32216787 ARHGAP12 0.33 5.82 0.3 1.39e-8 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs6840360 0.571 rs10026670 chr4:152539212 C/T cg22705602 chr4:152727874 NA -0.32 -6.35 -0.32 6.8e-10 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.57 0.46 2.2e-19 Electroencephalogram traits; LIHC cis rs473651 0.935 rs472357 chr2:239355454 A/G cg21699342 chr2:239360505 ASB1 -0.37 -7.23 -0.36 3.14e-12 Multiple system atrophy; LIHC cis rs600806 0.888 rs638542 chr1:109845252 G/A cg23091122 chr1:110024289 SYPL2 -0.46 -5.94 -0.31 7.02e-9 Intelligence (multi-trait analysis); LIHC cis rs11683229 0.704 rs35589581 chr2:63107944 T/C cg17519650 chr2:63277830 OTX1 -0.52 -5.73 -0.3 2.15e-8 Protein quantitative trait loci; LIHC cis rs2354432 0.607 rs10900350 chr1:146828017 T/G cg25205988 chr1:146714368 CHD1L 0.83 9.53 0.46 3.06e-19 Mitochondrial DNA levels; LIHC cis rs12022452 0.591 rs11208356 chr1:41006931 A/G cg25568243 chr1:40974465 DEM1 0.45 5.89 0.3 9.26e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3106136 0.527 rs2883 chr4:95158610 A/T cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.25 -0.45 2.45e-18 Capecitabine sensitivity; LIHC cis rs7940866 0.903 rs1820353 chr11:130870765 A/G cg12179176 chr11:130786555 SNX19 0.51 7.38 0.37 1.19e-12 Schizophrenia; LIHC cis rs6750047 0.932 rs11124631 chr2:38274908 A/G cg07380506 chr2:38303506 CYP1B1 -0.53 -6.56 -0.33 2e-10 Cutaneous malignant melanoma;Melanoma; LIHC cis rs780096 0.546 rs715325 chr2:27725572 C/A cg21747090 chr2:27597821 SNX17 -0.46 -6.93 -0.35 2.15e-11 Total body bone mineral density; LIHC cis rs929354 0.772 rs1182444 chr7:157024510 A/G cg17757837 chr7:157058334 UBE3C -0.72 -11.76 -0.54 4.98e-27 Body mass index; LIHC cis rs2067615 0.524 rs10778500 chr12:107074410 T/A cg15890332 chr12:107067104 RFX4 0.27 6.3 0.32 9.42e-10 Heart rate; LIHC cis rs644799 0.965 rs10831430 chr11:95509638 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.7 10.07 0.48 4.63e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 0.610 rs6987118 chr8:58147851 G/T cg21448741 chr8:58168803 NA 0.32 5.99 0.31 5.23e-9 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg21782813 chr7:2030301 MAD1L1 -0.55 -9.95 -0.47 1.17e-20 Bipolar disorder and schizophrenia; LIHC cis rs9549328 0.800 rs9549620 chr13:113633421 T/A cg08528486 chr13:113648767 MCF2L -0.39 -6.36 -0.33 6.59e-10 Systolic blood pressure; LIHC cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg23758822 chr17:41437982 NA 0.94 17.9 0.7 5.08e-51 Menopause (age at onset); LIHC cis rs9814567 0.712 rs9838467 chr3:134332222 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC cis rs2075371 1.000 rs2241336 chr7:133979578 A/G cg11752832 chr7:134001865 SLC35B4 0.5 7.56 0.38 3.62e-13 Mean platelet volume; LIHC cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs7072216 0.763 rs3750601 chr10:100174561 C/A cg26618903 chr10:100175079 PYROXD2 -0.4 -6.33 -0.32 7.67e-10 Metabolite levels; LIHC cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg06418219 chr1:154948305 SHC1;CKS1B -0.53 -7.68 -0.38 1.64e-13 Prostate cancer; LIHC cis rs2274273 0.682 rs1187876 chr14:55495199 A/T cg01864836 chr14:55583639 NA 0.36 6.07 0.31 3.46e-9 Protein biomarker; LIHC cis rs4144743 1.000 rs72823473 chr17:45321775 A/T cg18085866 chr17:45331354 ITGB3 -0.57 -8.21 -0.41 4.51e-15 Body mass index; LIHC trans rs4650994 0.967 rs4650992 chr1:178515135 A/T cg05059571 chr16:84539110 KIAA1609 -0.38 -6.35 -0.32 6.9e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9649465 1.000 rs3958047 chr7:123327936 G/C cg03229431 chr7:123269106 ASB15 -0.38 -8.13 -0.4 8.02e-15 Migraine; LIHC cis rs7677751 0.806 rs4864858 chr4:55089953 T/A cg17187183 chr4:55093834 PDGFRA 0.67 8.4 0.41 1.2e-15 Corneal astigmatism; LIHC cis rs801193 0.660 rs974239 chr7:66213491 G/A cg12463550 chr7:65579703 CRCP 0.4 5.79 0.3 1.64e-8 Aortic root size; LIHC cis rs6088590 0.687 rs6088580 chr20:33285053 G/C cg24642439 chr20:33292090 TP53INP2 0.51 7.18 0.36 4.41e-12 Coronary artery disease; LIHC cis rs10744422 0.800 rs2649902 chr12:123243687 G/A cg07706471 chr12:123319906 HIP1R -0.57 -7.36 -0.37 1.36e-12 Schizophrenia; LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg03354898 chr7:1950403 MAD1L1 -0.37 -5.74 -0.3 2.07e-8 Bipolar disorder and schizophrenia; LIHC cis rs7267979 0.565 rs13040726 chr20:25559881 T/G cg24626310 chr20:25276739 ABHD12;PYGB -0.44 -6.02 -0.31 4.47e-9 Liver enzyme levels (alkaline phosphatase); LIHC trans rs801193 0.967 rs2707841 chr7:66157020 A/G cg26939375 chr7:64535504 NA 0.42 6.77 0.34 5.53e-11 Aortic root size; LIHC cis rs4925166 1 rs4925166 chr17:18210810 T/G cg08201673 chr17:18167551 SMCR7 0.39 6.07 0.31 3.41e-9 Multiple sclerosis; LIHC cis rs950169 0.579 rs11633088 chr15:84672181 A/T cg17507749 chr15:85114479 UBE2QP1 -0.69 -6.56 -0.33 2.03e-10 Schizophrenia; LIHC cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg22442454 chr1:209979470 IRF6 0.38 5.8 0.3 1.49e-8 Cleft lip with or without cleft palate; LIHC trans rs61931739 0.500 rs34080094 chr12:34547952 G/A cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.54e-19 Morning vs. evening chronotype; LIHC cis rs60871478 1.000 rs62432860 chr7:807522 G/C cg04727924 chr7:799746 HEATR2 -0.58 -8.56 -0.42 3.97e-16 Cerebrospinal P-tau181p levels; LIHC cis rs8177179 0.505 rs1405023 chr3:133481128 T/C cg12373951 chr3:133503437 NA -0.51 -7.64 -0.38 2.24e-13 Iron status biomarkers (transferrin levels); LIHC cis rs6754311 0.597 rs6760329 chr2:136544752 A/G cg07169764 chr2:136633963 MCM6 -0.79 -12.08 -0.55 3.15e-28 Mosquito bite size; LIHC cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg25364880 chr3:44379878 C3orf23 0.58 7.97 0.4 2.36e-14 Depressive symptoms; LIHC cis rs7100689 0.577 rs9420349 chr10:82031160 T/C cg01528321 chr10:82214614 TSPAN14 0.81 10.83 0.51 1.07e-23 Post bronchodilator FEV1; LIHC cis rs9902453 0.689 rs56788338 chr17:28186557 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 13.8 0.6 9.39e-35 Coffee consumption (cups per day); LIHC cis rs7520050 0.966 rs4660317 chr1:46326226 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11212260 0.512 rs7121072 chr11:107174439 C/A cg25435332 chr11:107328525 CWF19L2 0.74 6.86 0.35 3.29e-11 IgG glycosylation; LIHC cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg07061783 chr6:25882402 NA -0.81 -11.29 -0.52 2.55e-25 Urate levels; LIHC cis rs8044995 0.563 rs1110572 chr16:68396119 A/G cg09835421 chr16:68378352 PRMT7 -0.81 -9.3 -0.45 1.68e-18 Schizophrenia; LIHC cis rs2153535 0.580 rs1414346 chr6:8471574 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs7089973 0.628 rs11196953 chr10:116607707 A/G cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs12477438 0.765 rs2309520 chr2:99570477 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.53 7.55 0.38 3.99e-13 Chronic sinus infection; LIHC cis rs2580764 0.541 rs2968786 chr2:55264859 C/G cg09592903 chr2:55203963 RTN4 0.69 12.84 0.57 4.61e-31 Mean platelet volume; LIHC cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5769707 0.837 rs5769709 chr22:50021757 C/T cg07959070 chr22:50026188 C22orf34 -0.33 -8.37 -0.41 1.53e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs3857067 0.806 rs34396894 chr4:95097600 T/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.78 -0.39 8.4e-14 QT interval; LIHC cis rs8031584 0.679 rs34017474 chr15:31230611 T/C cg19680485 chr15:31195859 MTMR15 -0.53 -7.98 -0.4 2.31e-14 Huntington's disease progression; LIHC cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg06634786 chr22:41940651 POLR3H 0.73 7.59 0.38 3.16e-13 Vitiligo; LIHC cis rs921968 0.643 rs492400 chr2:219349752 C/T cg17980119 chr2:219472607 PLCD4 0.35 6.02 0.31 4.62e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs2180341 0.782 rs4897214 chr6:127723625 G/T cg27446573 chr6:127587934 RNF146 0.79 13.15 0.58 3.06e-32 Breast cancer; LIHC cis rs2832191 0.671 rs2832212 chr21:30511417 G/A cg08807101 chr21:30365312 RNF160 -0.43 -6.11 -0.31 2.68e-9 Dental caries; LIHC cis rs9303280 0.776 rs11078926 chr17:38062976 G/A cg11212589 chr17:38028394 ZPBP2 0.35 7.08 0.36 8.3e-12 Self-reported allergy; LIHC cis rs35110281 0.782 rs2246602 chr21:45064296 C/A cg21573476 chr21:45109991 RRP1B -0.54 -10.29 -0.49 8.35e-22 Mean corpuscular volume; LIHC cis rs12824058 0.678 rs11614163 chr12:130814621 C/G cg24838063 chr12:130822603 PIWIL1 0.66 9.38 0.45 9.74e-19 Menopause (age at onset); LIHC cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs644799 0.710 rs3017756 chr11:95537358 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.64 0.56 2.6e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs35110281 0.667 rs4819285 chr21:45118970 C/T cg21573476 chr21:45109991 RRP1B 0.56 10.86 0.51 8.12e-24 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg12463550 chr7:65579703 CRCP -0.64 -6.7 -0.34 8.82e-11 Diabetic kidney disease; LIHC cis rs9486719 1.000 rs2472882 chr6:96863474 C/T cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC trans rs2840044 0.711 rs225301 chr17:33922411 T/A cg19694781 chr19:47549865 TMEM160 -0.94 -10.36 -0.49 4.72e-22 Response to radiotherapy in cancer (late toxicity); LIHC trans rs2749592 0.550 rs4934881 chr10:37914346 A/C cg27523141 chr10:43048294 ZNF37B -0.38 -6.5 -0.33 2.83e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs921968 0.548 rs13427522 chr2:219438359 C/T cg17980119 chr2:219472607 PLCD4 0.33 5.75 0.3 1.93e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg06420487 chr17:61919686 SMARCD2 0.46 6.3 0.32 9.34e-10 Height; LIHC cis rs35306767 0.953 rs34405399 chr10:981015 G/A cg20503657 chr10:835505 NA 0.87 10.02 0.48 6.8e-21 Eosinophil percentage of granulocytes; LIHC trans rs7618501 0.699 rs2681781 chr3:49898273 A/G cg21659725 chr3:3221576 CRBN 0.74 11.57 0.53 2.4e-26 Intelligence (multi-trait analysis); LIHC cis rs7959452 0.590 rs11177628 chr12:69765421 G/A cg20891283 chr12:69753455 YEATS4 0.9 19.5 0.73 1.79e-57 Blood protein levels; LIHC cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg16145915 chr7:1198662 ZFAND2A -0.4 -10.14 -0.48 2.62e-21 Longevity;Endometriosis; LIHC cis rs10876993 0.890 rs1678539 chr12:58060359 A/G cg15848620 chr12:58087721 OS9 -0.54 -7.29 -0.37 2.1e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs7432375 0.901 rs4038587 chr3:136381368 A/C cg21827317 chr3:136751795 NA -0.44 -5.82 -0.3 1.37e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs6754311 0.731 rs10207652 chr2:136588478 T/A cg07169764 chr2:136633963 MCM6 -0.68 -10.2 -0.48 1.66e-21 Mosquito bite size; LIHC cis rs8062405 1.000 rs4788099 chr16:28855727 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1669338 0.588 rs62228634 chr3:3184985 A/G cg16797762 chr3:3221439 CRBN -0.81 -7.35 -0.37 1.49e-12 White matter integrity; LIHC cis rs72781680 0.799 rs17508218 chr2:23976536 C/T cg08917208 chr2:24149416 ATAD2B 0.82 7.41 0.37 1.01e-12 Lymphocyte counts; LIHC cis rs6977660 0.619 rs4721823 chr7:19785888 G/C cg07541023 chr7:19748670 TWISTNB 0.44 6.47 0.33 3.4e-10 Thyroid stimulating hormone; LIHC cis rs17270561 0.666 rs12209856 chr6:25793673 G/A cg17691542 chr6:26056736 HIST1H1C 0.41 5.71 0.3 2.46e-8 Iron status biomarkers; LIHC trans rs11098499 0.954 rs2389803 chr4:120393511 A/G cg25214090 chr10:38739885 LOC399744 -0.56 -8.79 -0.43 7.24e-17 Corneal astigmatism; LIHC cis rs9300255 0.602 rs1790116 chr12:123618544 G/T cg00376283 chr12:123451042 ABCB9 0.65 7.35 0.37 1.45e-12 Neutrophil percentage of white cells; LIHC cis rs57502260 0.704 rs55975204 chr11:68249124 C/T cg16797656 chr11:68205561 LRP5 0.48 6.07 0.31 3.36e-9 Total body bone mineral density (age 45-60); LIHC cis rs8077889 1.000 rs17675122 chr17:41886190 A/G cg26893861 chr17:41843967 DUSP3 0.98 10.72 0.5 2.58e-23 Triglycerides; LIHC cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg10802521 chr3:52805072 NEK4 -0.42 -6.78 -0.34 5.22e-11 Bipolar disorder; LIHC cis rs9303401 0.614 rs34843288 chr17:57103140 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.46 0.56 1.21e-29 Cognitive test performance; LIHC cis rs2576037 0.545 rs9948405 chr18:44494527 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.71 11.11 0.51 1.12e-24 Personality dimensions; LIHC cis rs6938 0.534 rs11072512 chr15:75204026 C/T cg14664628 chr15:75095509 CSK -0.5 -6.56 -0.33 2.01e-10 Breast cancer; LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs7107174 1.000 rs2373115 chr11:78091150 G/T cg02023728 chr11:77925099 USP35 0.41 7.79 0.39 8.14e-14 Testicular germ cell tumor; LIHC cis rs2444240 0.935 rs4936509 chr11:120041444 C/T cg04390734 chr11:120039366 NA 0.32 6.17 0.32 1.95e-9 Corneal curvature; LIHC cis rs6964587 1.000 rs2282972 chr7:91666369 C/T cg17063962 chr7:91808500 NA 1.02 19.62 0.73 5.89e-58 Breast cancer; LIHC cis rs10838687 0.800 rs7928073 chr11:47361857 C/T cg26139080 chr11:47293733 MADD -0.42 -5.77 -0.3 1.78e-8 Proinsulin levels; LIHC cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.16 -0.36 5.11e-12 Diabetic kidney disease; LIHC cis rs6831352 0.918 rs13143133 chr4:100054970 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs875971 1.000 rs6945843 chr7:65734783 G/A cg18876405 chr7:65276391 NA -0.37 -6.72 -0.34 7.54e-11 Aortic root size; LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg00091569 chr3:40428383 ENTPD3 0.38 6.36 0.33 6.38e-10 Renal cell carcinoma; LIHC cis rs9902453 0.791 rs9904051 chr17:28244122 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 13.99 0.6 1.78e-35 Coffee consumption (cups per day); LIHC cis rs2806561 0.765 rs652706 chr1:23514246 G/A cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.49e-11 Height; LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg22963979 chr7:1858916 MAD1L1 -0.43 -7.01 -0.35 1.26e-11 Bipolar disorder and schizophrenia; LIHC trans rs4927850 1.000 rs4927850 chr3:195751630 C/T cg21051086 chr3:73046214 PPP4R2 0.37 6.09 0.31 3.08e-9 Pancreatic cancer; LIHC cis rs11122272 0.668 rs2808616 chr1:231554993 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.66 10.47 0.49 1.96e-22 Hemoglobin concentration; LIHC cis rs910316 0.763 rs175435 chr14:75612025 A/G cg08847533 chr14:75593920 NEK9 0.84 16.94 0.68 3.62e-47 Height; LIHC cis rs36051895 0.589 rs6476946 chr9:5195275 C/G cg02405213 chr9:5042618 JAK2 0.63 9.86 0.47 2.3e-20 Pediatric autoimmune diseases; LIHC cis rs7927592 0.513 rs7950129 chr11:68202903 A/G cg01657329 chr11:68192670 LRP5 -0.54 -8.05 -0.4 1.38e-14 Total body bone mineral density; LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg21951975 chr1:209979733 IRF6 0.46 8.12 0.4 8.76e-15 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC cis rs3806843 0.966 rs10053945 chr5:140160127 C/T cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs12701220 0.504 rs12702092 chr7:1145868 G/A cg09177884 chr7:1199841 ZFAND2A -0.52 -5.79 -0.3 1.6e-8 Bronchopulmonary dysplasia; LIHC cis rs826838 1.000 rs7315028 chr12:38710523 G/A cg26384229 chr12:38710491 ALG10B 1.06 14.86 0.63 6.89e-39 Heart rate; LIHC cis rs1018836 0.828 rs12548806 chr8:91564256 C/T cg16814680 chr8:91681699 NA -0.59 -9.26 -0.45 2.35e-18 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs7224737 1.000 rs9915255 chr17:40284191 C/T cg20291162 chr17:40259547 DHX58 -0.4 -6.26 -0.32 1.12e-9 Fibrinogen levels; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.75 -12.49 -0.56 9.68e-30 Prudent dietary pattern; LIHC cis rs6088590 1.000 rs910870 chr20:33292893 T/C cg06115741 chr20:33292138 TP53INP2 0.55 7.98 0.4 2.27e-14 Coronary artery disease; LIHC cis rs61990749 0.597 rs2032781 chr14:78214875 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.61 10.16 0.48 2.37e-21 Fibroblast growth factor basic levels; LIHC cis rs4150161 0.591 rs3785036 chr16:84219810 T/G cg10106505 chr16:84220380 TAF1C -0.96 -9.1 -0.44 7.36e-18 Systolic blood pressure response to hydrochlorothiazide in hypertension; LIHC cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg18867708 chr6:26865862 GUSBL1 -0.56 -8.55 -0.42 4.13e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs4819052 0.808 rs2838825 chr21:46655651 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.66 9.74 0.47 6.02e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs66569888 0.607 rs11687271 chr2:106727456 G/A cg16099169 chr2:106886729 NA -0.63 -6.82 -0.35 4.18e-11 Facial morphology (factor 23); LIHC cis rs3809863 0.602 rs7225700 chr17:45391804 T/C cg25173405 chr17:45401733 C17orf57 -0.58 -8.47 -0.42 7.36e-16 Glaucoma (primary open-angle); LIHC trans rs7618501 1.000 rs7431106 chr3:49808374 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.81 15.13 0.63 6.04e-40 Intelligence (multi-trait analysis); LIHC cis rs7903847 0.620 rs17112676 chr10:99122288 G/A cg06359132 chr10:99160096 RRP12 -0.4 -6.15 -0.32 2.19e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7310409 0.544 rs1169292 chr12:121426478 C/T cg02403541 chr12:121454288 C12orf43 0.46 7.65 0.38 2.08e-13 Liver enzyme levels (gamma-glutamyl transferase);C-reactive protein;Pancreatic cancer; LIHC cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg18252515 chr7:66147081 NA -1.24 -16.0 -0.65 2.11e-43 Diabetic kidney disease; LIHC trans rs950169 0.649 rs12911612 chr15:84691014 T/C cg24036039 chr1:3397125 ARHGEF16 0.37 6.19 0.32 1.71e-9 Schizophrenia; LIHC cis rs1552244 0.554 rs17050704 chr3:10045734 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC trans rs1814175 0.765 rs1722003 chr11:49895896 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.55e-73 Height; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg24707616 chr17:16342815 NCRNA00188;SNORD49B;SNORD49A -0.5 -6.35 -0.32 6.79e-10 Facial morphology (factor 20); LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg09033563 chr22:24373618 LOC391322 -0.43 -5.94 -0.31 6.87e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg07424592 chr7:64974309 NA 0.82 9.52 0.46 3.35e-19 Diabetic kidney disease; LIHC cis rs7772486 0.701 rs2244308 chr6:146213706 C/T cg23711669 chr6:146136114 FBXO30 0.61 10.76 0.5 1.96e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7927771 0.864 rs2868459 chr11:47454972 C/G cg20307385 chr11:47447363 PSMC3 -0.48 -6.22 -0.32 1.42e-9 Subjective well-being; LIHC cis rs35306767 0.761 rs12770910 chr10:1050318 A/G cg26597838 chr10:835615 NA 0.9 8.69 0.43 1.54e-16 Eosinophil percentage of granulocytes; LIHC cis rs34779708 0.966 rs2045918 chr10:35418517 T/G cg03585969 chr10:35415529 CREM 0.88 13.18 0.58 2.35e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg13770153 chr20:60521292 NA 0.56 12.13 0.55 2.15e-28 Obesity-related traits; LIHC cis rs651907 0.557 rs3864012 chr3:101397623 T/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.73 -0.34 7.32e-11 Colorectal cancer; LIHC cis rs875971 0.508 rs10258739 chr7:66062935 A/T cg11764359 chr7:65958608 NA -0.61 -9.27 -0.45 2.1e-18 Aortic root size; LIHC cis rs2302190 0.769 rs7218778 chr17:56664248 T/G cg05425664 chr17:57184151 TRIM37 -0.47 -5.89 -0.3 9.43e-9 Vitamin D levels; LIHC cis rs8114671 0.527 rs6088650 chr20:33514465 C/T cg07148914 chr20:33460835 GGT7 -0.62 -9.37 -0.45 1.02e-18 Height; LIHC cis rs7617773 0.780 rs13082158 chr3:48372470 T/C cg11946769 chr3:48343235 NME6 0.92 11.74 0.54 5.67e-27 Coronary artery disease; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg07677032 chr17:61819896 STRADA 0.42 6.15 0.32 2.12e-9 Prudent dietary pattern; LIHC trans rs61931739 0.500 rs11053208 chr12:34460029 A/G cg26384229 chr12:38710491 ALG10B 0.63 7.99 0.4 2.06e-14 Morning vs. evening chronotype; LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg18876405 chr7:65276391 NA 0.34 5.98 0.31 5.68e-9 Calcium levels; LIHC cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg25894440 chr7:65020034 NA -0.56 -6.48 -0.33 3.21e-10 Diabetic kidney disease; LIHC trans rs877282 0.945 rs35342920 chr10:790484 T/C cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs7520050 0.966 rs785489 chr1:46576390 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.8 0.3 1.5e-8 Red blood cell count;Reticulocyte count; LIHC cis rs4716602 0.596 rs12386634 chr7:156158373 G/A cg16983916 chr7:156159713 NA -0.32 -5.87 -0.3 1.03e-8 Anti-saccade response; LIHC cis rs9486715 0.830 rs1475748 chr6:97034143 T/C cg06623918 chr6:96969491 KIAA0776 -0.86 -15.43 -0.64 3.99e-41 Headache; LIHC cis rs10508774 0.810 rs12244832 chr10:32872120 C/T cg01819863 chr10:32635814 EPC1 0.61 5.83 0.3 1.31e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs919433 0.680 rs6710530 chr2:198277551 G/A cg03934865 chr2:198174659 NA 0.54 8.27 0.41 3.03e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6582630 0.537 rs11520294 chr12:38402705 C/A cg26384229 chr12:38710491 ALG10B 0.84 10.51 0.49 1.45e-22 Drug-induced liver injury (flucloxacillin); LIHC cis rs1534166 0.647 rs9876158 chr3:133508300 T/C cg12373951 chr3:133503437 NA -0.49 -6.87 -0.35 2.98e-11 Alcohol consumption (transferrin glycosylation); LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.05 0.4 1.35e-14 Platelet count; LIHC cis rs2242116 0.761 rs6780601 chr3:46965856 A/G cg02527881 chr3:46936655 PTH1R -0.46 -9.26 -0.45 2.3e-18 Birth weight; LIHC cis rs11675119 0.501 rs9309716 chr2:3493355 A/G cg10845886 chr2:3471009 TTC15 -0.36 -6.35 -0.32 6.82e-10 Neurofibrillary tangles; LIHC cis rs12602486 1.000 rs16940540 chr17:42229702 C/A cg08193365 chr17:42277699 NA 1.05 7.39 0.37 1.16e-12 Glycated hemoglobin levels; LIHC cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg20090690 chr10:134436459 INPP5A 0.44 5.8 0.3 1.5e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs651907 0.535 rs4342086 chr3:101503765 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.07 0.51 1.47e-24 Colorectal cancer; LIHC cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg13047869 chr3:10149882 C3orf24 0.5 5.98 0.31 5.48e-9 Alzheimer's disease; LIHC trans rs13405020 0.578 rs2198439 chr2:138218082 A/C cg10008445 chr10:105630969 NA -0.37 -6.09 -0.31 2.99e-9 Non-small cell lung cancer; LIHC cis rs5769765 0.862 rs138857 chr22:50199589 C/T cg26441486 chr22:50317300 CRELD2 0.37 6.08 0.31 3.19e-9 Schizophrenia; LIHC cis rs67478160 0.643 rs2223937 chr14:104286380 A/G cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.19 -0.36 4.24e-12 Schizophrenia; LIHC cis rs1862618 0.671 rs2591966 chr5:56233688 T/G cg12311346 chr5:56204834 C5orf35 0.46 6.39 0.33 5.32e-10 Initial pursuit acceleration; LIHC cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg20887711 chr4:1340912 KIAA1530 -0.47 -7.2 -0.36 3.85e-12 Obesity-related traits; LIHC cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg26818010 chr10:134567672 INPP5A -0.8 -9.8 -0.47 3.9e-20 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1065656 0.589 rs391543 chr16:1915583 T/G cg00564555 chr16:1970112 NA 0.26 5.92 0.3 8.04e-9 Insulin-like growth factors; LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs10499694 0.735 rs2044859 chr7:50612562 A/G cg14593290 chr7:50529359 DDC 0.41 7.06 0.36 9.52e-12 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20977600 chr12:106751964 POLR3B -0.44 -6.09 -0.31 3.05e-9 Pancreatic cancer; LIHC cis rs644799 0.511 rs10831420 chr11:95478209 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.79 12.29 0.55 5.46e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2073499 0.935 rs3755832 chr3:50305234 G/A cg08207895 chr3:50388901 TUSC4;CYB561D2 0.63 6.58 0.34 1.78e-10 Schizophrenia; LIHC cis rs3741151 1.000 rs74795285 chr11:73033387 A/G cg17517138 chr11:73019481 ARHGEF17 0.91 6.91 0.35 2.38e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs589448 0.902 rs315124 chr12:69771727 G/A cg14784868 chr12:69753453 YEATS4 0.97 22.6 0.77 7.56e-70 Cerebrospinal fluid biomarker levels; LIHC cis rs600806 0.888 rs11102971 chr1:109872370 C/T cg23091122 chr1:110024289 SYPL2 -0.46 -6.06 -0.31 3.63e-9 Intelligence (multi-trait analysis); LIHC cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg14262678 chr6:151773367 RMND1;C6orf211 0.54 8.03 0.4 1.63e-14 Menarche (age at onset); LIHC cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 12.68 0.57 1.81e-30 Alzheimer's disease; LIHC cis rs6089584 0.888 rs6061981 chr20:60618973 T/C cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs116095464 0.558 rs56081398 chr5:247318 C/T cg22857025 chr5:266934 NA -1.56 -16.35 -0.66 8.71e-45 Breast cancer; LIHC trans rs7246657 0.943 rs7408563 chr19:37808585 G/C cg10208301 chr11:6592745 DNHD1 0.49 6.57 0.33 1.89e-10 Coronary artery calcification; LIHC cis rs73001065 0.536 rs10408596 chr19:19512657 A/T cg03709012 chr19:19516395 GATAD2A 0.95 10.58 0.5 7.9399999999999994e-23 LDL cholesterol; LIHC cis rs4478858 0.775 rs6701667 chr1:31707971 A/C cg00250761 chr1:31883323 NA -0.27 -6.13 -0.31 2.46e-9 Alcohol dependence; LIHC cis rs2576037 0.526 rs1893427 chr18:44434987 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.56 0.5 9.43e-23 Personality dimensions; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17200204 chr3:43732323 ABHD5 0.48 6.56 0.33 1.96e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 1.000 rs2755240 chr1:67477339 T/G cg02640540 chr1:67518911 SLC35D1 0.43 5.95 0.31 6.69e-9 Lymphocyte percentage of white cells; LIHC cis rs919433 0.783 rs2565165 chr2:198233575 T/G cg10820045 chr2:198174542 NA 0.56 8.88 0.43 3.78e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs561341 1.000 rs7216102 chr17:30259450 A/G cg13647721 chr17:30228624 UTP6 0.68 6.85 0.35 3.52e-11 Hip circumference adjusted for BMI; LIHC cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.68 9.97 0.47 1.04e-20 Lymphocyte counts; LIHC cis rs919433 0.648 rs6434933 chr2:198426960 G/A cg03934865 chr2:198174659 NA 0.51 7.82 0.39 6.55e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1878931 0.582 rs27238 chr16:3441223 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -8.3 -0.41 2.36e-15 Body mass index (adult); LIHC cis rs6964587 0.900 rs4279 chr7:91764128 C/A cg17063962 chr7:91808500 NA 1.05 21.05 0.75 1.13e-63 Breast cancer; LIHC cis rs7264396 0.563 rs2425119 chr20:34324216 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.47e-16 Total cholesterol levels; LIHC cis rs6963495 0.818 rs55983796 chr7:105170941 C/T cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs7044106 0.762 rs1886337 chr9:123443776 G/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.55 0.38 4.11e-13 Hip circumference adjusted for BMI; LIHC cis rs4700695 0.841 rs153367 chr5:65419170 G/A cg21114390 chr5:65439923 SFRS12 -0.5 -6.71 -0.34 8.03e-11 Facial morphology (factor 19); LIHC cis rs11792861 0.781 rs72607159 chr9:111764270 C/T cg13535736 chr9:111863775 C9orf5 -0.4 -5.98 -0.31 5.52e-9 Menarche (age at onset); LIHC cis rs9368481 0.524 rs9393768 chr6:26885619 A/G cg18867708 chr6:26865862 GUSBL1 0.55 8.3 0.41 2.37e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs7927592 0.956 rs7124078 chr11:68298633 G/T cg20283391 chr11:68216788 NA -0.52 -7.71 -0.38 1.37e-13 Total body bone mineral density; LIHC cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.99 8.93 0.43 2.62e-17 Platelet count; LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg27305525 chr1:154955752 FLAD1 0.34 6.12 0.31 2.52e-9 Metabolic traits; LIHC cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg11644478 chr21:40555479 PSMG1 -0.8 -9.99 -0.48 8.79e-21 Cognitive function; LIHC cis rs7772486 0.875 rs864390 chr6:146315035 G/T cg13319975 chr6:146136371 FBXO30 -0.36 -6.06 -0.31 3.63e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11229555 0.874 rs11605683 chr11:58350794 T/A cg15696309 chr11:58395628 NA -0.71 -8.73 -0.43 1.11e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.78 -0.3 1.71e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2204008 0.684 rs11514164 chr12:38036494 C/T cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs9902453 0.791 rs28492945 chr17:28223982 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 14.0 0.6 1.67e-35 Coffee consumption (cups per day); LIHC trans rs11098499 0.754 rs12509621 chr4:120249660 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.31 0.41 2.32e-15 Corneal astigmatism; LIHC cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg06481639 chr22:41940642 POLR3H -0.69 -7.07 -0.36 8.6e-12 Vitiligo; LIHC cis rs986417 1.000 rs1254255 chr14:60831342 G/A cg27398547 chr14:60952738 C14orf39 -0.79 -9.02 -0.44 1.36e-17 Gut microbiota (bacterial taxa); LIHC cis rs3099143 1.000 rs3110379 chr15:77095175 A/G cg21673338 chr15:77095150 SCAPER -0.48 -7.49 -0.38 5.94e-13 Recalcitrant atopic dermatitis; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs1865760 0.713 rs9461229 chr6:25992279 G/T cg18357526 chr6:26021779 HIST1H4A 0.41 6.14 0.32 2.31e-9 Height; LIHC cis rs4930103 0.564 rs1618613 chr11:1969888 G/A cg23202291 chr11:1979235 NA -0.52 -6.63 -0.34 1.29e-10 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs2637266 0.967 rs2579748 chr10:78328313 T/C cg18941641 chr10:78392320 NA 0.29 6.23 0.32 1.38e-9 Pulmonary function; LIHC cis rs7258015 0.909 rs3176769 chr19:10447034 A/G cg13981319 chr19:10446556 ICAM3 0.46 7.21 0.36 3.68e-12 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs17376456 0.877 rs7728736 chr5:93404277 C/T cg25358565 chr5:93447407 FAM172A 1.12 10.25 0.48 1.1e-21 Diabetic retinopathy; LIHC cis rs11122272 0.735 rs2572251 chr1:231514243 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.56 -0.5 9.46e-23 Hemoglobin concentration; LIHC cis rs919433 0.889 rs787998 chr2:198216092 A/G cg03934865 chr2:198174659 NA 0.54 8.6 0.42 2.86e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7618915 1.000 rs34569561 chr3:52287293 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.41 6.53 0.33 2.35e-10 Bipolar disorder; LIHC trans rs7618501 0.633 rs2624843 chr3:49997963 G/A cg21659725 chr3:3221576 CRBN 0.67 10.88 0.51 7.04e-24 Intelligence (multi-trait analysis); LIHC cis rs9921222 1.000 rs9921222 chr16:375782 A/G cg26944245 chr16:421049 TMEM8A;MRPL28 -0.36 -6.25 -0.32 1.2e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs950776 0.518 rs12902493 chr15:78819275 C/G cg22563815 chr15:78856949 CHRNA5 0.35 6.21 0.32 1.5e-9 Sudden cardiac arrest; LIHC cis rs34779708 0.931 rs4934719 chr10:35376769 T/C cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs910316 1.000 rs910316 chr14:75626042 A/C cg08847533 chr14:75593920 NEK9 0.87 18.9 0.71 4.62e-55 Height; LIHC cis rs3784262 0.967 rs11630835 chr15:58269462 C/T cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.33 -0.32 7.73e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05582585 chr5:150138399 DCTN4 0.42 6.37 0.33 6.27e-10 Calcium levels; LIHC cis rs7917772 0.582 rs10786683 chr10:104320476 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.88 0.39 4.45e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4144743 0.641 rs67696888 chr17:45355116 A/G cg18085866 chr17:45331354 ITGB3 -0.47 -6.34 -0.32 7.39e-10 Body mass index; LIHC cis rs921968 0.643 rs4674321 chr2:219511368 G/A cg02985541 chr2:219472218 PLCD4 0.43 7.83 0.39 6.23e-14 Mean corpuscular hemoglobin concentration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22387939 chr2:71175719 ATP6V1B1 0.44 6.33 0.32 7.57e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7520050 0.966 rs785503 chr1:46595868 T/C cg03146154 chr1:46216737 IPP -0.37 -6.16 -0.32 1.99e-9 Red blood cell count;Reticulocyte count; LIHC trans rs8073060 0.586 rs225296 chr17:33924847 C/G cg19694781 chr19:47549865 TMEM160 -1.22 -13.29 -0.58 8.49e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg26794364 chr3:9691143 MTMR14 -0.48 -6.23 -0.32 1.36e-9 Hepatitis; LIHC cis rs9871864 0.645 rs9856107 chr3:20353124 C/T cg00235661 chr3:20228976 SGOL1 -0.33 -6.41 -0.33 4.91e-10 Behavioural disinhibition (generation interaction); LIHC cis rs12200782 0.799 rs72845515 chr6:26646871 A/G cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs514406 0.792 rs481440 chr1:53344976 C/T cg16325326 chr1:53192061 ZYG11B 0.39 5.72 0.3 2.28e-8 Monocyte count; LIHC cis rs875971 0.862 rs6971059 chr7:66067032 A/G cg18252515 chr7:66147081 NA 0.45 6.56 0.33 1.97e-10 Aortic root size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24930797 chr15:66083595 DENND4A 0.42 6.37 0.33 6.12e-10 Cognitive function; LIHC cis rs11098499 0.954 rs10017543 chr4:120321420 G/A cg09307838 chr4:120376055 NA 0.77 11.96 0.54 8.81e-28 Corneal astigmatism; LIHC cis rs10791323 0.601 rs7946883 chr11:133733864 T/C cg06766960 chr11:133703094 NA -0.62 -9.7 -0.46 8.01e-20 Childhood ear infection; LIHC trans rs9929218 0.861 rs3114409 chr16:68732049 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.65 -9.47 -0.46 4.8e-19 Colorectal cancer; LIHC cis rs3862030 0.720 rs11593971 chr10:104234090 C/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -7.29 -0.37 2.19e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs6752107 0.967 rs6431661 chr2:234167421 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.34 0.41 1.9e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs929354 0.739 rs1182439 chr7:157027367 G/A cg05182265 chr7:156933206 UBE3C 0.32 6.0 0.31 5.14e-9 Body mass index; LIHC cis rs1538970 0.962 rs4660849 chr1:45819872 A/G cg24296786 chr1:45957014 TESK2 0.5 7.45 0.37 7.81e-13 Platelet count; LIHC cis rs763121 0.889 rs9607557 chr22:39040279 G/A cg06022373 chr22:39101656 GTPBP1 0.72 14.58 0.62 9.14e-38 Menopause (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10190329 chr10:126605450 NA -0.45 -6.62 -0.34 1.43e-10 Cognitive function; LIHC cis rs67478160 0.608 rs4906368 chr14:104242397 A/C cg08213375 chr14:104286397 PPP1R13B 0.52 10.01 0.48 7.45e-21 Schizophrenia; LIHC cis rs743757 1.000 rs2236984 chr3:50495487 A/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.47 7.4 0.37 1.07e-12 Diastolic blood pressure; LIHC cis rs9611565 0.546 rs34077262 chr22:42061639 A/G cg06634786 chr22:41940651 POLR3H 0.59 6.51 0.33 2.63e-10 Vitiligo; LIHC cis rs6066825 0.666 rs6019374 chr20:47303812 A/G cg18078177 chr20:47281410 PREX1 0.44 7.16 0.36 5.04e-12 Colorectal cancer; LIHC cis rs9611565 0.569 rs6002328 chr22:41710034 T/C cg06634786 chr22:41940651 POLR3H -0.51 -5.91 -0.3 8.17e-9 Vitiligo; LIHC cis rs6748734 0.894 rs4675869 chr2:241827696 A/G cg08694578 chr2:241835147 C2orf54 -0.51 -7.16 -0.36 4.88e-12 Urinary metabolites; LIHC cis rs826838 0.559 rs1843891 chr12:38617018 T/C cg26384229 chr12:38710491 ALG10B 0.43 6.49 0.33 2.93e-10 Heart rate; LIHC cis rs897984 0.568 rs11862962 chr16:30909706 C/G cg02466173 chr16:30829666 NA -0.43 -6.25 -0.32 1.23e-9 Dementia with Lewy bodies; LIHC cis rs9457247 0.663 rs9459845 chr6:167440501 C/G cg12798992 chr6:167411361 FGFR1OP 0.46 7.19 0.36 4.2e-12 Crohn's disease; LIHC cis rs1941023 0.503 rs10792269 chr11:60117126 C/T cg08716584 chr11:60157161 MS4A7 -0.34 -7.74 -0.39 1.16e-13 Congenital heart disease (maternal effect); LIHC trans rs1814175 0.645 rs7115592 chr11:50013243 A/G cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs317689 0.690 rs607797 chr12:69646010 T/C cg19645103 chr12:69753606 YEATS4 -0.45 -6.05 -0.31 3.7e-9 Response to diuretic therapy; LIHC cis rs10193935 0.901 rs6727657 chr2:42632117 A/G cg27598129 chr2:42591480 NA -0.71 -11.23 -0.52 3.89e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg00656387 chr3:40428638 ENTPD3 -0.5 -8.67 -0.42 1.83e-16 Renal cell carcinoma; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00239003 chr19:45458398 CLPTM1 -0.49 -6.04 -0.31 4.1e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs929354 0.742 rs10274687 chr7:156933181 T/G cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs2153535 0.601 rs1928183 chr6:8530018 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.57 0.53 2.35e-26 Motion sickness; LIHC cis rs1057239 0.510 rs3766694 chr1:175143207 T/C cg00321850 chr1:175162397 KIAA0040 -0.36 -6.6 -0.34 1.59e-10 Diastolic blood pressure; LIHC cis rs6121246 0.528 rs6060252 chr20:30191084 A/G cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs2072499 0.932 rs2540183 chr1:156164885 C/G cg24450063 chr1:156163899 SLC25A44 1.05 17.32 0.68 1.08e-48 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs1335633 chr6:8448800 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.8 0.54 3.56e-27 Motion sickness; LIHC cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg02290350 chr8:58132656 NA 0.48 9.55 0.46 2.59e-19 Developmental language disorder (linguistic errors); LIHC cis rs8017423 0.791 rs7146250 chr14:90711703 A/G cg04374321 chr14:90722782 PSMC1 0.74 14.16 0.61 3.7e-36 Mortality in heart failure; LIHC cis rs79387448 0.701 rs76943877 chr2:102970677 T/C cg09003973 chr2:102972529 NA 1.17 9.75 0.47 5.68e-20 Gut microbiota (bacterial taxa); LIHC cis rs523522 0.962 rs10744752 chr12:120900554 T/G cg12219531 chr12:120966889 COQ5 0.64 12.26 0.55 6.84e-29 High light scatter reticulocyte count; LIHC cis rs600806 0.672 rs1144594 chr1:110029475 A/G cg11161837 chr1:110010384 SYPL2 0.42 5.71 0.3 2.41e-8 Intelligence (multi-trait analysis); LIHC cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg19045956 chr2:200819837 C2orf60;C2orf47 0.33 5.92 0.31 7.67e-9 Osteoporosis; LIHC cis rs7927592 0.626 rs11228279 chr11:68309680 C/T cg16797656 chr11:68205561 LRP5 -0.5 -8.88 -0.43 3.94e-17 Total body bone mineral density; LIHC cis rs950776 0.790 rs2067808 chr15:78911780 G/A cg06917634 chr15:78832804 PSMA4 0.63 8.28 0.41 2.83e-15 Sudden cardiac arrest; LIHC cis rs4919694 1.000 rs7083328 chr10:104769268 G/A cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs7572733 0.515 rs6724526 chr2:198858401 A/G cg03934865 chr2:198174659 NA 0.46 6.61 0.34 1.44e-10 Dermatomyositis; LIHC cis rs75908454 1.000 rs79670745 chr6:169954036 A/G cg19338460 chr6:170058176 WDR27 -0.82 -7.66 -0.38 1.91e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs3091242 0.933 rs7541095 chr1:25761291 T/C cg09222892 chr1:25734099 RHCE -0.47 -8.66 -0.42 1.85e-16 Erythrocyte sedimentation rate; LIHC cis rs10791097 0.703 rs11222360 chr11:130730871 C/T cg09137382 chr11:130731461 NA 0.42 6.52 0.33 2.47e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs28374715 0.617 rs16971733 chr15:41562030 C/A cg18705301 chr15:41695430 NDUFAF1 -0.39 -5.72 -0.3 2.3e-8 Ulcerative colitis; LIHC cis rs3617 0.625 rs2535633 chr3:52859630 C/G cg11645453 chr3:52864694 ITIH4 -0.22 -6.02 -0.31 4.49e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs713477 0.967 rs8020152 chr14:55907025 T/A cg13175173 chr14:55914753 NA -0.34 -7.86 -0.39 4.97e-14 Pediatric bone mineral content (femoral neck); LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg21279826 chr15:52358353 MAPK6 0.37 6.16 0.32 2.06e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs921968 0.541 rs3731867 chr2:219472734 G/A cg02985541 chr2:219472218 PLCD4 -0.4 -6.4 -0.33 5.17e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs12744310 0.887 rs12047875 chr1:41785176 C/T cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.92e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11190604 1.000 rs74650218 chr10:102293830 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.08 0.4 1.1e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2797160 0.684 rs1832937 chr6:125985934 A/G cg05901451 chr6:126070800 HEY2 0.44 7.32 0.37 1.77e-12 Endometrial cancer; LIHC cis rs7959452 0.535 rs1350166 chr12:69636314 G/T cg22834771 chr12:69754056 YEATS4 -0.44 -7.47 -0.37 6.94e-13 Blood protein levels; LIHC cis rs9393692 0.905 rs1124999 chr6:26287043 G/T cg05868516 chr6:26286170 HIST1H4H 0.45 6.85 0.35 3.47e-11 Educational attainment; LIHC cis rs3849570 0.961 rs3821548 chr3:81758728 C/G cg07356753 chr3:81810745 GBE1 -0.64 -10.55 -0.5 1.07e-22 Waist circumference;Body mass index; LIHC cis rs1707322 1.000 rs6695421 chr1:46380207 T/C cg03146154 chr1:46216737 IPP 0.47 7.62 0.38 2.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2806561 0.808 rs2235546 chr1:23409538 A/G cg19743168 chr1:23544995 NA 0.37 6.85 0.35 3.52e-11 Height; LIHC cis rs1775715 0.614 rs806808 chr10:32381186 T/C cg14930904 chr10:32216787 ARHGAP12 -0.38 -6.48 -0.33 3.25e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs3820068 0.705 rs7533125 chr1:15883744 T/C cg17385448 chr1:15911702 AGMAT 0.41 6.8 0.35 4.65e-11 Systolic blood pressure; LIHC cis rs12984174 0.877 rs408484 chr19:18139771 C/T cg21649277 chr19:18117794 ARRDC2 0.67 6.2 0.32 1.59e-9 Pulmonary function in asthmatics; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05951308 chr12:72080128 TMEM19 -0.49 -6.48 -0.33 3.2e-10 Systolic blood pressure; LIHC trans rs1814175 0.791 rs10839395 chr11:49846274 G/T cg15704280 chr7:45808275 SEPT13 -1.02 -23.78 -0.79 1.79e-74 Height; LIHC cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg06212747 chr3:49208901 KLHDC8B 0.6 8.07 0.4 1.22e-14 Menarche (age at onset); LIHC cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg05590025 chr7:65112418 INTS4L2 -0.66 -7.2 -0.36 3.94e-12 Diabetic kidney disease; LIHC cis rs7582180 0.629 rs11123826 chr2:100936276 G/T cg14675211 chr2:100938903 LONRF2 -0.55 -8.55 -0.42 4.23e-16 Intelligence (multi-trait analysis); LIHC cis rs4575098 0.681 rs10908824 chr1:161111931 A/G cg08545169 chr1:161169143 NDUFS2;ADAMTS4 0.43 7.78 0.39 8.77e-14 Monocyte percentage of white cells; LIHC cis rs7100689 0.577 rs9421464 chr10:82043426 C/T cg00277334 chr10:82204260 NA -0.5 -6.21 -0.32 1.49e-9 Post bronchodilator FEV1; LIHC cis rs7937890 0.874 rs6486191 chr11:14403739 G/A cg23387056 chr11:14280742 SPON1 -0.42 -5.8 -0.3 1.48e-8 Mitochondrial DNA levels; LIHC cis rs7845219 0.539 rs13271644 chr8:95853948 A/G cg09323728 chr8:95962352 TP53INP1 -0.28 -5.93 -0.31 7.44e-9 Type 2 diabetes; LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.58 8.84 0.43 5.01e-17 Height; LIHC cis rs10847980 0.590 rs77970074 chr12:123292186 T/G cg18912006 chr12:123335444 HIP1R 0.73 7.17 0.36 4.65e-12 Adiponectin levels; LIHC trans rs561341 1.000 rs484175 chr17:30309041 G/A cg20587970 chr11:113659929 NA -1.38 -11.71 -0.53 7.6e-27 Hip circumference adjusted for BMI; LIHC cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg10802521 chr3:52805072 NEK4 -0.45 -7.7 -0.38 1.49e-13 Electroencephalogram traits; LIHC cis rs9309473 0.519 rs7598901 chr2:73675844 C/T cg20560298 chr2:73613845 ALMS1 0.36 5.78 0.3 1.72e-8 Metabolite levels; LIHC cis rs4684776 0.867 rs2305686 chr3:11350553 C/T cg00170343 chr3:11313890 ATG7 -0.53 -7.28 -0.37 2.31e-12 Small vessel stroke; LIHC cis rs9916302 0.904 rs11078910 chr17:37671269 G/T cg03013999 chr17:37608204 MED1 0.35 5.78 0.3 1.71e-8 Glomerular filtration rate (creatinine); LIHC cis rs9549260 1.000 rs9549260 chr13:41254104 G/T cg21288729 chr13:41239152 FOXO1 0.52 7.79 0.39 7.89e-14 Red blood cell count; LIHC cis rs9911578 0.817 rs304264 chr17:56749628 A/G cg05425664 chr17:57184151 TRIM37 -0.56 -8.33 -0.41 2.03e-15 Intelligence (multi-trait analysis); LIHC cis rs422249 0.512 rs174566 chr11:61592362 A/G cg27386326 chr11:61587980 NA 0.72 15.86 0.65 7.59e-43 Trans fatty acid levels; LIHC cis rs2845885 1.000 rs11231698 chr11:63877163 C/T cg24431193 chr11:63883947 FLRT1;MACROD1 0.59 7.41 0.37 9.85e-13 Body mass index; LIHC cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.98 0.54 7.4e-28 Colorectal cancer; LIHC cis rs2777491 0.872 rs7163649 chr15:41586798 A/G cg18705301 chr15:41695430 NDUFAF1 -0.54 -8.06 -0.4 1.25e-14 Ulcerative colitis; LIHC cis rs2749592 0.611 rs2505199 chr10:38392457 G/A cg25427524 chr10:38739819 LOC399744 -0.64 -11.51 -0.53 3.92e-26 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs10762653 0.541 rs11001300 chr10:76884960 C/T cg27380788 chr16:4526765 HMOX2 0.48 6.24 0.32 1.26e-9 Pneumonia; LIHC cis rs7589728 0.563 rs78685993 chr2:88447026 T/C cg07952391 chr2:88470173 THNSL2 0.79 7.52 0.38 4.77e-13 Plasma clusterin levels; LIHC cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg23205692 chr1:25664452 TMEM50A 0.4 6.53 0.33 2.35e-10 Plateletcrit;Mean corpuscular volume; LIHC cis rs28595532 0.545 rs72677057 chr4:119264162 A/T cg21605333 chr4:119757512 SEC24D 0.79 6.67 0.34 1.02e-10 Cannabis dependence symptom count; LIHC cis rs10779751 1.000 rs11121702 chr1:11293147 C/T cg08854313 chr1:11322531 MTOR 0.81 11.44 0.53 6.82e-26 Body mass index; LIHC cis rs4903214 0.895 rs7157482 chr14:74712696 C/T cg11132536 chr14:74711944 VSX2 -0.24 -6.14 -0.32 2.29e-9 Inflammatory bowel disease; LIHC cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg05368731 chr17:41323189 NBR1 0.72 12.43 0.56 1.65e-29 Menopause (age at onset); LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg05064044 chr6:292385 DUSP22 0.49 6.57 0.33 1.89e-10 Menopause (age at onset); LIHC cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg08859206 chr1:53392774 SCP2 0.35 5.85 0.3 1.16e-8 Monocyte count; LIHC trans rs111706465 1 rs111706465 chr2:239452382 A/C cg01134436 chr17:81009848 B3GNTL1 0.74 6.36 0.33 6.55e-10 Morning vs. evening chronotype; LIHC cis rs7772486 0.754 rs9386133 chr6:146141213 A/G cg23711669 chr6:146136114 FBXO30 0.63 11.12 0.52 1.01e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 0.967 rs10804790 chr3:161039300 T/A cg03342759 chr3:160939853 NMD3 -0.71 -8.42 -0.41 1.08e-15 Morning vs. evening chronotype; LIHC cis rs5769765 0.908 rs7410601 chr22:50317187 C/T cg02269571 chr22:50332266 NA -0.64 -8.68 -0.42 1.68e-16 Schizophrenia; LIHC cis rs1552244 0.882 rs17050660 chr3:10001772 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.6 9.08 0.44 8.72e-18 Alzheimer's disease; LIHC cis rs600806 0.713 rs10857786 chr1:110010110 C/G cg11161837 chr1:110010384 SYPL2 0.46 6.3 0.32 9.14e-10 Intelligence (multi-trait analysis); LIHC cis rs523522 0.962 rs10849753 chr12:120910813 C/T cg12219531 chr12:120966889 COQ5 0.65 12.61 0.56 3.24e-30 High light scatter reticulocyte count; LIHC cis rs11626933 0.959 rs17799226 chr14:90754538 C/T cg04374321 chr14:90722782 PSMC1 0.47 6.53 0.33 2.34e-10 Gut microbiota (bacterial taxa); LIHC cis rs12478296 0.892 rs11893879 chr2:243010411 G/A cg18898632 chr2:242989856 NA -0.47 -6.48 -0.33 3.25e-10 Obesity-related traits; LIHC cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg05368731 chr17:41323189 NBR1 0.67 10.93 0.51 4.82e-24 Menopause (age at onset); LIHC cis rs10504073 0.631 rs341813 chr8:50039916 T/C cg00325661 chr8:49890786 NA 0.32 7.26 0.37 2.64e-12 Blood metabolite ratios; LIHC trans rs208520 1.000 rs12212063 chr6:66985148 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.98 0.35 1.52e-11 Exhaled nitric oxide output; LIHC cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg23758822 chr17:41437982 NA 0.93 17.41 0.69 4.79e-49 Menopause (age at onset); LIHC cis rs11098499 0.618 rs35265692 chr4:120325135 T/C cg09307838 chr4:120376055 NA 0.78 12.32 0.55 3.97e-29 Corneal astigmatism; LIHC cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg22029157 chr1:209979665 IRF6 0.47 7.74 0.39 1.11e-13 Cleft lip with or without cleft palate; LIHC cis rs875971 0.660 rs10215132 chr7:66054406 C/A cg18876405 chr7:65276391 NA -0.44 -7.85 -0.39 5.3e-14 Aortic root size; LIHC cis rs7098414 0.511 rs12262228 chr10:82160425 C/T cg00277334 chr10:82204260 NA -0.61 -9.99 -0.48 8.77e-21 Post bronchodilator FEV1; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.04e-14 Height; LIHC cis rs4908768 0.906 rs11121207 chr1:8681848 C/A cg20416874 chr1:8611966 RERE 0.54 7.66 0.38 1.91e-13 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3008870 0.785 rs10889651 chr1:67463513 A/T cg02640540 chr1:67518911 SLC35D1 -0.41 -6.39 -0.33 5.49e-10 Lymphocyte percentage of white cells; LIHC cis rs1385374 0.642 rs10847691 chr12:129287449 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -5.82 -0.3 1.33e-8 Systemic lupus erythematosus; LIHC cis rs10540 1.000 rs71487296 chr11:500282 G/A cg03576123 chr11:487126 PTDSS2 -1.12 -8.21 -0.41 4.43e-15 Body mass index; LIHC cis rs875971 0.965 rs9969301 chr7:65781655 G/A cg18252515 chr7:66147081 NA 0.42 6.03 0.31 4.37e-9 Aortic root size; LIHC cis rs12594515 0.967 rs11857628 chr15:45998206 C/T cg19682013 chr15:45996608 NA 0.39 6.57 0.33 1.92e-10 Waist circumference;Weight; LIHC trans rs3960554 0.569 rs1894761 chr7:75876754 C/T cg19862616 chr7:65841803 NCRNA00174 -0.6 -9.21 -0.45 3.38e-18 Eotaxin levels; LIHC cis rs3008870 0.755 rs10789219 chr1:67417742 A/C cg02640540 chr1:67518911 SLC35D1 0.41 6.44 0.33 4.02e-10 Lymphocyte percentage of white cells; LIHC cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg17747265 chr1:1875780 NA -0.59 -11.23 -0.52 4.11e-25 Body mass index; LIHC cis rs11758351 0.925 rs10452600 chr6:26192502 C/A cg16070018 chr6:26224392 HIST1H3E 0.57 6.83 0.35 3.8e-11 Gout;Renal underexcretion gout; LIHC cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs2841277 0.708 rs10083374 chr14:105402994 T/C cg21017887 chr14:105400489 NA 0.66 12.76 0.57 9.24e-31 Rheumatoid arthritis; LIHC cis rs1559088 0.600 rs58173463 chr19:33596749 C/T cg27124370 chr19:33622961 WDR88 0.6 8.96 0.44 2.14e-17 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9486715 0.838 rs9400034 chr6:96954566 C/T cg06623918 chr6:96969491 KIAA0776 0.86 15.21 0.64 2.77e-40 Headache; LIHC cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg18357526 chr6:26021779 HIST1H4A 0.83 11.26 0.52 3.21e-25 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26155979 chr10:105110866 PCGF6 -0.44 -6.44 -0.33 4.08e-10 Pancreatic cancer; LIHC cis rs9425766 0.640 rs16846439 chr1:173824038 T/G cg06124660 chr1:173389066 NA -0.33 -6.4 -0.33 5.25e-10 Life satisfaction; LIHC cis rs1046896 0.553 rs3744160 chr17:80828303 G/A cg02711726 chr17:80685570 FN3KRP -0.44 -7.95 -0.39 2.76e-14 Glycated hemoglobin levels; LIHC cis rs225245 0.782 rs225293 chr17:33925906 A/G cg05299278 chr17:33885742 SLFN14 0.22 5.97 0.31 6.05e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs722599 0.639 rs12882676 chr14:75272433 A/G cg11812906 chr14:75593930 NEK9 0.4 6.07 0.31 3.33e-9 IgG glycosylation; LIHC cis rs4803468 1.000 rs55986560 chr19:41939835 C/T cg09537434 chr19:41945824 ATP5SL 1.02 20.69 0.75 3.04e-62 Height; LIHC cis rs1059312 0.522 rs3825181 chr12:129279264 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.48 7.43 0.37 8.5e-13 Systemic lupus erythematosus; LIHC cis rs9297145 0.565 rs56132062 chr7:98778198 C/T cg05967295 chr7:98741636 SMURF1 -0.39 -6.49 -0.33 3.03e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.66 9.67 0.46 1.03e-19 Lymphocyte counts; LIHC cis rs6500602 0.893 rs6500596 chr16:4470027 G/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 5.85 0.3 1.18e-8 Schizophrenia; LIHC cis rs17818399 0.510 rs1451153 chr2:46799852 G/T cg02822958 chr2:46747628 ATP6V1E2 0.42 6.72 0.34 7.39e-11 Height; LIHC cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg08499158 chr17:42289980 UBTF -0.48 -7.69 -0.38 1.63e-13 Total body bone mineral density; LIHC cis rs7107174 1.000 rs1567890 chr11:78101700 T/C cg02023728 chr11:77925099 USP35 0.46 8.57 0.42 3.54e-16 Testicular germ cell tumor; LIHC cis rs2257205 0.667 rs6503879 chr17:56888183 T/A cg12560992 chr17:57184187 TRIM37 0.68 7.44 0.37 8.24e-13 Pancreatic cancer; LIHC cis rs875971 0.522 rs709604 chr7:65497434 A/G cg26939375 chr7:64535504 NA -0.47 -7.23 -0.36 3.24e-12 Aortic root size; LIHC cis rs1559088 1.000 rs1974783 chr19:33551507 C/G cg27124370 chr19:33622961 WDR88 0.46 7.05 0.36 9.79e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.597 rs7746618 chr6:146281367 T/C cg23711669 chr6:146136114 FBXO30 -0.63 -9.19 -0.45 3.79e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg20090690 chr10:134436459 INPP5A 0.45 5.87 0.3 1.02e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9818758 0.607 rs13077498 chr3:49313978 C/T cg07636037 chr3:49044803 WDR6 -0.82 -8.25 -0.41 3.54e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs4862750 0.914 rs1991255 chr4:187875340 G/A cg22105103 chr4:187893119 NA 0.33 8.09 0.4 1.07e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs1005277 0.579 rs1780138 chr10:38501654 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs10426930 0.607 rs858415 chr19:5055996 C/T cg18473234 chr19:5097819 KDM4B -0.57 -6.86 -0.35 3.15e-11 Monocyte percentage of white cells; LIHC cis rs757081 0.667 rs1987694 chr11:17107648 G/C cg15432903 chr11:17409602 KCNJ11 -0.42 -5.84 -0.3 1.24e-8 Systolic blood pressure; LIHC trans rs7615952 0.611 rs9681518 chr3:125615130 A/G cg07211511 chr3:129823064 LOC729375 -0.83 -8.7 -0.43 1.44e-16 Blood pressure (smoking interaction); LIHC cis rs6840360 0.615 rs72728173 chr4:152469373 C/T cg22705602 chr4:152727874 NA -0.32 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs174601 0.721 rs174530 chr11:61546592 A/G cg27386326 chr11:61587980 NA 0.69 14.41 0.61 3.89e-37 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC trans rs9929218 0.581 rs7203337 chr16:68774800 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.83 18.15 0.7 4.75e-52 Colorectal cancer; LIHC cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs56163509 1 rs56163509 chr16:28864471 A/G cg07451762 chr16:28383216 NA 0.33 6.13 0.31 2.44e-9 Tonsillectomy;Mean corpuscular volume; LIHC cis rs16828019 0.789 rs34216154 chr1:41670907 G/A cg03387723 chr1:41708464 SCMH1 -0.44 -7.13 -0.36 6.14e-12 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs8077486 chr17:41212805 C/T cg25072359 chr17:41440525 NA 0.4 6.42 0.33 4.43e-10 Menopause (age at onset); LIHC cis rs7666738 0.715 rs116787789 chr4:98718720 G/A cg05340658 chr4:99064831 C4orf37 0.64 11.61 0.53 1.65e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs7224314 1.000 rs62084077 chr17:65386837 G/A cg01507342 chr17:65387096 PITPNC1 -0.48 -5.92 -0.3 7.84e-9 Diisocyanate-induced asthma; LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.88 -0.3 9.77e-9 Menopause (age at onset); LIHC cis rs600806 0.888 rs3879450 chr1:109909149 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg08219700 chr8:58056026 NA 0.5 6.62 0.34 1.39e-10 Developmental language disorder (linguistic errors); LIHC cis rs2549003 1.000 rs2070723 chr5:131823187 A/G cg21138405 chr5:131827807 IRF1 0.38 9.8 0.47 3.79e-20 Asthma (sex interaction); LIHC cis rs2073300 1.000 rs6036423 chr20:23459810 A/C cg12062639 chr20:23401060 NAPB 0.78 9.87 0.47 2.16e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs11098499 0.754 rs9991959 chr4:120253773 C/T cg25214090 chr10:38739885 LOC399744 -0.51 -8.32 -0.41 2.07e-15 Corneal astigmatism; LIHC cis rs2204008 0.811 rs8189445 chr12:38276295 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.57e-21 Bladder cancer; LIHC cis rs916888 0.773 rs199457 chr17:44795469 C/T cg01570182 chr17:44337453 NA 1.02 10.23 0.48 1.29e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs13108904 0.901 rs13119532 chr4:1304505 G/C cg05665937 chr4:1216051 CTBP1 0.46 6.05 0.31 3.78e-9 Obesity-related traits; LIHC cis rs9303280 0.806 rs11870965 chr17:38030205 T/A cg11212589 chr17:38028394 ZPBP2 0.35 7.18 0.36 4.31e-12 Self-reported allergy; LIHC cis rs7961581 0.748 rs7314537 chr12:71620125 A/G cg05756094 chr12:71608604 NA 0.38 6.01 0.31 4.82e-9 Type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05051957 chr8:141522459 CHRAC1 0.44 6.32 0.32 8.05e-10 Pancreatic cancer; LIHC cis rs6964587 0.967 rs28399886 chr7:91638451 A/G cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs992157 0.710 rs10167446 chr2:219056866 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.73 11.99 0.54 6.75e-28 Colorectal cancer; LIHC cis rs2637266 0.655 rs7902535 chr10:78460889 C/T cg18941641 chr10:78392320 NA 0.28 6.04 0.31 4.09e-9 Pulmonary function; LIHC cis rs509477 1.000 rs11660848 chr18:32574010 T/C cg23791764 chr18:32556832 MAPRE2 -0.52 -7.33 -0.37 1.63e-12 Cerebrospinal fluid AB1-42 levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09578018 chr15:60883649 RORA 0.49 7.73 0.39 1.2e-13 Cognitive function; LIHC cis rs12744310 0.943 rs34862272 chr1:41768653 A/C cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs903552 1.000 rs4965386 chr15:102003207 G/A cg06707286 chr15:102010195 PCSK6 -0.45 -6.42 -0.33 4.43e-10 Diabetic kidney disease; LIHC cis rs7412746 0.634 rs72704658 chr1:150833010 T/C cg15448220 chr1:150897856 SETDB1 0.39 5.8 0.3 1.55e-8 Melanoma; LIHC cis rs568617 0.953 rs658938 chr11:65651830 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.44 -0.33 4.17e-10 Crohn's disease; LIHC cis rs1707322 0.721 rs28641748 chr1:46212836 A/G cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs711245 0.545 rs848617 chr2:36811298 G/C cg09467607 chr2:36825704 FEZ2 0.38 6.28 0.32 1e-9 Height; LIHC cis rs9612 1.000 rs1059 chr19:44268348 C/T cg08581076 chr19:44259116 C19orf61 0.61 7.49 0.38 6.11e-13 Exhaled nitric oxide output; LIHC cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg02359409 chr6:42947317 PEX6 -0.47 -6.63 -0.34 1.28e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs61990749 0.597 rs8016416 chr14:78213100 T/A cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.75 -0.39 1.02e-13 Fibroblast growth factor basic levels; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg05484376 chr2:27715224 FNDC4 0.37 6.33 0.32 7.68e-10 Total body bone mineral density; LIHC trans rs208520 0.634 rs3909071 chr6:66836947 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.29 -0.41 2.67e-15 Exhaled nitric oxide output; LIHC cis rs116095464 0.558 rs10076655 chr5:239464 G/C cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.78e-52 Breast cancer; LIHC trans rs10842750 1.000 rs10842750 chr12:26690565 G/T cg11072887 chr6:37322624 RNF8 -0.59 -6.76 -0.34 5.8e-11 Kashin-Beck disease; LIHC cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg12292205 chr6:26970375 C6orf41 -0.48 -8.15 -0.4 6.74e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs11677370 0.603 rs1454242 chr2:3848532 G/A cg17052675 chr2:3827356 NA -0.52 -6.6 -0.34 1.55e-10 Type 2 diabetes; LIHC cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg11890956 chr21:40555474 PSMG1 1.0 14.18 0.61 3.28e-36 Cognitive function; LIHC cis rs1538970 1.000 rs1538970 chr1:45847562 G/A cg24296786 chr1:45957014 TESK2 -0.49 -7.29 -0.37 2.15e-12 Platelet count; LIHC cis rs9902453 0.904 rs7218379 chr17:28402737 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.73 -0.6 1.82e-34 Coffee consumption (cups per day); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg26521561 chr2:198283608 SF3B1 -0.25 -6.07 -0.31 3.49e-9 Calcium levels; LIHC cis rs11098499 0.754 rs2964 chr4:120240131 T/C cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs11122272 0.735 rs2355872 chr1:231478489 A/T cg06096015 chr1:231504339 EGLN1 0.5 9.3 0.45 1.73e-18 Hemoglobin concentration; LIHC cis rs7772486 0.790 rs2485632 chr6:146193228 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.96 -0.31 6.11e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03634708 chr10:32345420 KIF5B -0.43 -6.13 -0.31 2.47e-9 Pancreatic cancer; LIHC cis rs1568889 1.000 rs7102106 chr11:28343953 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.9 0.35 2.48e-11 Bipolar disorder; LIHC cis rs262147 0.610 rs2657363 chr7:158684273 C/T cg23730037 chr7:158596552 ESYT2 -0.71 -5.79 -0.3 1.64e-8 Hippocampal volume; LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg14709524 chr16:89940631 TCF25 0.5 6.38 0.33 5.66e-10 Skin colour saturation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26770187 chr3:14693171 C3orf19 0.45 7.34 0.37 1.6e-12 Cognitive function; LIHC cis rs12477438 0.520 rs2969379 chr2:99776686 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.24 24.75 0.8 3.3e-78 Chronic sinus infection; LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs2204008 0.713 rs12366709 chr12:38210179 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg06481639 chr22:41940642 POLR3H -0.67 -6.74 -0.34 6.54e-11 Vitiligo; LIHC cis rs1799949 0.965 rs7223952 chr17:41194885 T/C cg05368731 chr17:41323189 NBR1 0.68 11.3 0.52 2.29e-25 Menopause (age at onset); LIHC cis rs7772486 0.790 rs9376970 chr6:146241472 A/C cg13319975 chr6:146136371 FBXO30 0.38 6.12 0.31 2.53e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4073582 0.595 rs801739 chr11:65922589 A/G cg16950941 chr11:66035639 RAB1B 0.47 7.45 0.37 7.62e-13 Gout; LIHC cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg03188948 chr7:1209495 NA 0.49 6.95 0.35 1.86e-11 Longevity;Endometriosis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25372841 chr8:145675454 CYHR1 -0.4 -6.25 -0.32 1.24e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.620 rs11189165 chr10:99123457 A/G cg08345082 chr10:99160200 RRP12 -0.36 -5.96 -0.31 6.14e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7607369 0.572 rs629177 chr2:219454801 T/G cg02985541 chr2:219472218 PLCD4 0.41 6.66 0.34 1.1e-10 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.44 5.92 0.31 7.68e-9 Electroencephalogram traits; LIHC cis rs875971 0.660 rs28698552 chr7:66005018 A/G cg14393609 chr7:65229607 NA 0.37 5.81 0.3 1.4e-8 Aortic root size; LIHC cis rs5769765 0.954 rs5770739 chr22:50268014 C/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg06634786 chr22:41940651 POLR3H -0.81 -8.83 -0.43 5.65e-17 Vitiligo; LIHC cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg03264133 chr6:25882463 NA -0.59 -8.36 -0.41 1.65e-15 Blood metabolite levels; LIHC cis rs1892700 0.821 rs62227705 chr21:34919593 A/C cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.95e-8 Educational attainment; LIHC cis rs919433 0.963 rs1366837 chr2:198160501 T/C cg03934865 chr2:198174659 NA -0.61 -9.92 -0.47 1.49e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17401966 0.627 rs35859381 chr1:10466040 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.41 -0.33 4.76e-10 Hepatocellular carcinoma; LIHC trans rs1814175 0.817 rs1615305 chr11:49895222 T/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs3857067 0.772 rs4438731 chr4:95091384 A/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.74 -0.39 1.11e-13 QT interval; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6914276 chr6:8450435 A/T cg07606381 chr6:8435919 SLC35B3 -0.8 -11.85 -0.54 2.23e-27 Motion sickness; LIHC cis rs7945718 0.810 rs7930282 chr11:12835941 C/T cg25843174 chr11:12811716 TEAD1 0.35 8.07 0.4 1.21e-14 Educational attainment (years of education); LIHC cis rs7131987 0.934 rs7316004 chr12:29411698 C/T cg05697976 chr12:29376483 FAR2 0.33 6.76 0.34 6.05e-11 QT interval; LIHC cis rs67311347 0.822 rs9826847 chr3:40345312 A/T cg09455208 chr3:40491958 NA 0.32 5.98 0.31 5.73e-9 Renal cell carcinoma; LIHC cis rs1873147 0.569 rs8029221 chr15:63308583 C/T cg21584241 chr15:63341463 TPM1 0.44 6.35 0.32 6.75e-10 Orofacial clefts; LIHC cis rs2153535 0.601 rs4140585 chr6:8503298 T/A cg07606381 chr6:8435919 SLC35B3 0.8 11.97 0.54 8.17e-28 Motion sickness; LIHC cis rs763121 0.853 rs5757187 chr22:39021522 A/G cg21395723 chr22:39101663 GTPBP1 -0.38 -6.14 -0.32 2.28e-9 Menopause (age at onset); LIHC cis rs6449957 0.741 rs6882730 chr5:67464205 C/T cg23036683 chr5:67512108 NA 0.44 6.25 0.32 1.22e-9 Cleft lip with or without cleft palate; LIHC cis rs311392 0.934 rs376589 chr8:55088289 G/A cg20636351 chr8:55087400 NA -0.4 -8.07 -0.4 1.22e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs7582720 1.000 rs72936842 chr2:203773686 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs8044868 0.530 rs2241411 chr16:72144493 T/C cg16558253 chr16:72132732 DHX38 -0.4 -6.89 -0.35 2.68e-11 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs7727544 0.735 rs273914 chr5:131660431 A/T cg24060327 chr5:131705240 SLC22A5 -0.6 -8.61 -0.42 2.71e-16 Blood metabolite levels; LIHC trans rs8002861 0.935 rs7320988 chr13:44413523 C/T cg17145862 chr1:211918768 LPGAT1 0.58 10.88 0.51 7.03e-24 Leprosy; LIHC cis rs11663156 0.804 rs34563569 chr18:50900013 C/T cg24270629 chr18:50823537 DCC 0.47 6.48 0.33 3.19e-10 Intelligence (multi-trait analysis); LIHC cis rs782590 0.783 rs7594279 chr2:55812073 T/G cg18811423 chr2:55921094 PNPT1 0.9 14.43 0.62 3.47e-37 Metabolic syndrome; LIHC cis rs9733 0.519 rs7529194 chr1:150622620 A/T cg17724175 chr1:150552817 MCL1 0.46 9.36 0.45 1.12e-18 Tonsillectomy; LIHC cis rs11148252 0.595 rs9526968 chr13:53240183 T/C cg12458913 chr13:53173898 NA 0.48 7.87 0.39 4.62e-14 Lewy body disease; LIHC cis rs7903847 0.642 rs11189206 chr10:99167802 T/C cg20016023 chr10:99160130 RRP12 -0.43 -7.0 -0.35 1.35e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.81 0.35 4.44e-11 Bipolar disorder; LIHC cis rs7662987 0.540 rs2851278 chr4:100021253 G/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg16574807 chr4:6945745 TBC1D14 0.54 6.2 0.32 1.65e-9 Mean platelet volume; LIHC cis rs7044106 0.762 rs7044226 chr9:123466328 G/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 8.28 0.41 2.72e-15 Hip circumference adjusted for BMI; LIHC cis rs4478037 0.822 rs9827863 chr3:33118951 C/T cg16652328 chr3:33138982 GLB1;TMPPE 0.53 6.74 0.34 6.87e-11 Major depressive disorder; LIHC trans rs1814175 0.817 rs4881658 chr11:49941123 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg11764359 chr7:65958608 NA -0.57 -5.93 -0.31 7.25e-9 Diabetic kidney disease; LIHC cis rs4595586 0.546 rs11169801 chr12:39241429 G/A cg26384229 chr12:38710491 ALG10B 0.52 6.94 0.35 1.95e-11 Morning vs. evening chronotype; LIHC cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg27286337 chr10:134555280 INPP5A 0.88 13.54 0.59 9.29e-34 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7520050 0.966 rs10749860 chr1:46328210 C/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.34e-8 Red blood cell count;Reticulocyte count; LIHC cis rs250677 0.652 rs250680 chr5:148436024 T/C cg12140854 chr5:148520817 ABLIM3 -0.45 -6.1 -0.31 2.85e-9 Breast cancer; LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg07677032 chr17:61819896 STRADA 0.43 6.18 0.32 1.79e-9 Prudent dietary pattern; LIHC cis rs9549328 0.837 rs9549618 chr13:113628648 G/A cg04958157 chr13:113748321 MCF2L -0.35 -5.72 -0.3 2.37e-8 Systolic blood pressure; LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg24846343 chr22:24311635 DDTL 0.7 13.69 0.6 2.45e-34 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg26338869 chr17:61819248 STRADA 0.59 8.72 0.43 1.24e-16 Prudent dietary pattern; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.71 11.55 0.53 2.84e-26 Prudent dietary pattern; LIHC cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg05535760 chr7:792225 HEATR2 -0.48 -6.63 -0.34 1.33e-10 Perceived unattractiveness to mosquitoes; LIHC cis rs477692 0.935 rs568918 chr10:131414455 A/G cg05714579 chr10:131428358 MGMT 0.48 8.07 0.4 1.18e-14 Response to temozolomide; LIHC cis rs4555082 0.957 rs8022526 chr14:105756485 A/G cg06808227 chr14:105710500 BRF1 -0.57 -8.03 -0.4 1.6e-14 Mean platelet volume;Platelet distribution width; LIHC cis rs801193 0.569 rs2659908 chr7:66160822 G/A cg11764359 chr7:65958608 NA 0.76 12.98 0.57 1.3e-31 Aortic root size; LIHC cis rs11792861 0.926 rs76689835 chr9:111833792 G/A cg05043794 chr9:111880884 C9orf5 -0.29 -6.79 -0.34 5e-11 Menarche (age at onset); LIHC cis rs798554 0.797 rs798487 chr7:2802943 G/A cg19346786 chr7:2764209 NA -0.47 -7.09 -0.36 7.77e-12 Height; LIHC cis rs7615952 0.599 rs1875683 chr3:125732481 C/G cg05084668 chr3:125655381 ALG1L -0.4 -6.45 -0.33 3.76e-10 Blood pressure (smoking interaction); LIHC cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.52 0.33 2.5e-10 Bipolar disorder; LIHC cis rs4759375 1.000 rs4759377 chr12:123796849 C/T cg00376283 chr12:123451042 ABCB9 -0.5 -6.4 -0.33 5.02e-10 HDL cholesterol; LIHC cis rs8078723 1.000 rs709592 chr17:38175553 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.12 -0.44 6.77e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7520050 0.966 rs785488 chr1:46576095 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.8 0.3 1.5e-8 Red blood cell count;Reticulocyte count; LIHC cis rs11098699 0.821 rs7665722 chr4:124201501 A/G cg09941581 chr4:124220074 SPATA5 0.32 6.46 0.33 3.58e-10 Mosquito bite size; LIHC cis rs17152411 0.744 rs10901835 chr10:126589712 G/T cg07906193 chr10:126599966 NA -0.3 -5.87 -0.3 1.04e-8 Height; LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.05 -0.31 3.71e-9 Diastolic blood pressure; LIHC cis rs634534 0.622 rs531612 chr11:65705432 C/T cg02427764 chr11:65769310 BANF1;EIF1AD -0.42 -6.38 -0.33 5.67e-10 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs12477438 0.520 rs7604557 chr2:99747829 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs798554 0.836 rs798490 chr7:2801542 C/T cg19524238 chr7:2802976 GNA12 -0.38 -5.9 -0.3 8.69e-9 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14514174 chr9:99181512 ZNF367 0.5 6.45 0.33 3.72e-10 Lung function (FEV1/FVC); LIHC cis rs2637266 1.000 rs12251434 chr10:78345468 C/A cg18941641 chr10:78392320 NA 0.29 6.22 0.32 1.43e-9 Pulmonary function; LIHC cis rs2153535 0.580 rs2184584 chr6:8468407 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC trans rs4332037 0.539 rs868754 chr7:2033780 G/C cg11693508 chr17:37793320 STARD3 0.64 6.43 0.33 4.22e-10 Bipolar disorder; LIHC cis rs1065852 0.906 rs9611734 chr22:42502070 A/G cg00645731 chr22:42541494 CYP2D7P1 0.48 7.65 0.38 2.12e-13 Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels); LIHC cis rs9534288 0.830 rs1409435 chr13:46631660 G/A cg15192986 chr13:46630673 CPB2 -0.61 -8.89 -0.43 3.66e-17 Blood protein levels; LIHC cis rs61990749 0.544 rs7151211 chr14:78151901 C/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.59 -9.85 -0.47 2.5e-20 Fibroblast growth factor basic levels; LIHC cis rs6942756 1.000 rs11979476 chr7:128993756 G/T cg02491457 chr7:128862824 NA 0.65 9.93 0.47 1.39e-20 White matter hyperintensity burden; LIHC cis rs7927771 0.524 rs11039431 chr11:47872012 G/T cg20307385 chr11:47447363 PSMC3 0.74 11.02 0.51 2.29e-24 Subjective well-being; LIHC cis rs6456156 0.586 rs12213683 chr6:167460718 G/A cg07741184 chr6:167504864 NA 0.29 6.75 0.34 6.23e-11 Primary biliary cholangitis; LIHC cis rs8180040 0.966 rs59586735 chr3:47518325 C/T cg27129171 chr3:47204927 SETD2 -0.57 -9.78 -0.47 4.48e-20 Colorectal cancer; LIHC cis rs35160687 0.644 rs4832274 chr2:86529084 C/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.37 5.92 0.3 7.97e-9 Night sleep phenotypes; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23674352 chr6:100016770 CCNC -0.4 -6.07 -0.31 3.48e-9 Cognitive function; LIHC cis rs899997 0.862 rs11072787 chr15:78972977 T/C cg04896959 chr15:78267971 NA -0.35 -6.66 -0.34 1.11e-10 Coronary artery disease or large artery stroke; LIHC trans rs1814175 0.587 rs7937757 chr11:49978342 G/A cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC trans rs61931739 0.517 rs2636074 chr12:34064056 C/T cg26384229 chr12:38710491 ALG10B 0.43 6.04 0.31 3.94e-9 Morning vs. evening chronotype; LIHC cis rs2953174 0.720 rs2975794 chr2:241515813 C/T cg07929629 chr2:241523174 NA 0.59 6.83 0.35 3.85e-11 Bipolar disorder; LIHC cis rs637571 0.557 rs1204649 chr11:65702776 A/C cg02202077 chr11:65769826 EIF1AD;BANF1 0.41 5.99 0.31 5.24e-9 Eosinophil percentage of white cells; LIHC cis rs10744422 0.800 rs2649902 chr12:123243687 G/A cg22842854 chr12:123319900 HIP1R -0.64 -8.07 -0.4 1.24e-14 Schizophrenia; LIHC cis rs7511006 0.893 rs2038049 chr22:50654888 G/C cg16473166 chr22:50639996 SELO 0.59 8.81 0.43 6.19e-17 Obesity-related traits; LIHC cis rs11122272 0.670 rs2474632 chr1:231484361 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.18 0.44 4.12e-18 Hemoglobin concentration; LIHC cis rs798554 1.000 rs798536 chr7:2766383 G/A cg19346786 chr7:2764209 NA -0.47 -7.12 -0.36 6.58e-12 Height; LIHC cis rs561341 0.654 rs6505265 chr17:30172580 C/T cg13647721 chr17:30228624 UTP6 -0.74 -6.9 -0.35 2.57e-11 Hip circumference adjusted for BMI; LIHC cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg00656387 chr3:40428638 ENTPD3 -0.39 -6.35 -0.32 7.02e-10 Renal cell carcinoma; LIHC cis rs4853036 0.597 rs1048165 chr2:70131964 A/C cg02498382 chr2:70120550 SNRNP27 -0.4 -6.28 -0.32 1.02e-9 Colorectal or endometrial cancer; LIHC cis rs72949976 1.000 rs62186568 chr2:214033955 G/A cg08319019 chr2:214017104 IKZF2 -0.63 -6.79 -0.34 4.99e-11 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC trans rs208520 0.507 rs3903670 chr6:66812183 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.05 -21.06 -0.75 1.04e-63 Exhaled nitric oxide output; LIHC cis rs8062405 0.679 rs72793818 chr16:28893137 G/A cg16576597 chr16:28551801 NUPR1 0.38 6.16 0.32 2.1e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs79387448 0.626 rs80256362 chr2:103025501 A/G cg09003973 chr2:102972529 NA 1.1 8.81 0.43 6.58e-17 Gut microbiota (bacterial taxa); LIHC cis rs6448317 1.000 rs7698504 chr4:24939386 A/T cg21108841 chr4:24914750 CCDC149 -0.47 -6.0 -0.31 5e-9 Heschl's gyrus morphology; LIHC cis rs7727544 0.735 rs274566 chr5:131715011 A/G cg24060327 chr5:131705240 SLC22A5 0.59 8.46 0.42 8.12e-16 Blood metabolite levels; LIHC cis rs7582720 1.000 rs72934745 chr2:203744454 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2153535 0.580 rs1832100 chr6:8446956 G/A cg07606381 chr6:8435919 SLC35B3 0.78 11.53 0.53 3.21e-26 Motion sickness; LIHC cis rs798554 0.757 rs1182179 chr7:2873648 A/G cg13628971 chr7:2884303 GNA12 0.52 7.3 0.37 2.09e-12 Height; LIHC cis rs2637266 0.935 rs2252652 chr10:78405022 C/T cg18941641 chr10:78392320 NA 0.29 6.42 0.33 4.55e-10 Pulmonary function; LIHC cis rs1355223 0.583 rs2116085 chr11:34884001 C/A cg24088639 chr11:34937564 PDHX;APIP -0.38 -5.95 -0.31 6.46e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs10540 0.686 rs12806099 chr11:531572 G/A cg03576123 chr11:487126 PTDSS2 -1.0 -7.02 -0.35 1.21e-11 Body mass index; LIHC cis rs6598955 0.724 rs884533 chr1:26585657 G/T cg04990556 chr1:26633338 UBXN11 -0.62 -10.15 -0.48 2.47e-21 Obesity-related traits; LIHC cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg14004847 chr7:1930337 MAD1L1 -0.43 -6.49 -0.33 2.94e-10 Schizophrenia; LIHC cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs757110 0.690 rs35271178 chr11:17411020 C/T cg15432903 chr11:17409602 KCNJ11 0.59 9.04 0.44 1.14e-17 Type 2 diabetes; LIHC cis rs9896933 0.830 rs607544 chr17:80768760 C/G cg15664640 chr17:80829946 TBCD -0.57 -6.04 -0.31 4.06e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC trans rs3960554 0.808 rs78587454 chr7:75688672 G/A cg19862616 chr7:65841803 NCRNA00174 0.6 8.3 0.41 2.4e-15 Eotaxin levels; LIHC cis rs526231 0.819 rs568999 chr5:102601358 G/C cg05225461 chr5:102596755 C5orf30 0.38 5.89 0.3 9.25e-9 Primary biliary cholangitis; LIHC cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.74 0.3 2.09e-8 Bipolar disorder; LIHC cis rs7552404 0.731 rs12090849 chr1:76400261 A/G cg03433033 chr1:76189801 ACADM 0.51 6.53 0.33 2.43e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs67311347 1.000 rs897117 chr3:40437294 C/T cg00656387 chr3:40428638 ENTPD3 -0.4 -6.53 -0.33 2.35e-10 Renal cell carcinoma; LIHC cis rs1046896 1.000 rs1046917 chr17:80685655 A/G cg02398342 chr17:80708632 TBCD;FN3K -0.45 -6.9 -0.35 2.54e-11 Glycated hemoglobin levels; LIHC cis rs847649 1.000 rs28856331 chr7:102543763 T/G cg18108683 chr7:102477205 FBXL13 -0.49 -7.43 -0.37 8.6e-13 Morning vs. evening chronotype; LIHC cis rs2228479 0.541 rs12918575 chr16:89811151 A/G cg06558623 chr16:89946397 TCF25 0.83 11.58 0.53 2.18e-26 Skin colour saturation; LIHC cis rs6456156 0.586 rs13210649 chr6:167473193 T/G cg12798992 chr6:167411361 FGFR1OP 0.51 8.3 0.41 2.5e-15 Primary biliary cholangitis; LIHC cis rs3806843 0.966 rs2337986 chr5:140160622 C/T cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.24e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg15383120 chr6:291909 DUSP22 -0.47 -6.15 -0.32 2.15e-9 Menopause (age at onset); LIHC cis rs78456975 0.943 rs10470006 chr2:1580971 A/C cg01028140 chr2:1542097 TPO -0.47 -5.84 -0.3 1.23e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2386661 0.591 rs11255051 chr10:5653450 A/G cg17085576 chr10:5658249 NA -0.36 -6.47 -0.33 3.32e-10 Breast cancer; LIHC cis rs9611565 0.559 rs12483860 chr22:41961916 C/T cg03806693 chr22:41940476 POLR3H -0.87 -9.75 -0.47 5.67e-20 Vitiligo; LIHC cis rs35883536 0.647 rs7535762 chr1:101047534 A/G cg14515779 chr1:101123966 NA 0.5 6.9 0.35 2.56e-11 Monocyte count; LIHC cis rs1892700 0.764 rs62227703 chr21:34906317 A/G cg14850771 chr21:34775459 IFNGR2 -0.45 -5.91 -0.3 8.47e-9 Educational attainment; LIHC cis rs57590327 0.583 rs13062245 chr3:81833718 G/T cg07356753 chr3:81810745 GBE1 -0.57 -8.93 -0.43 2.64e-17 Extraversion; LIHC cis rs727505 1.000 rs66513837 chr7:124492763 A/G cg23710748 chr7:124431027 NA -0.33 -5.82 -0.3 1.37e-8 Lewy body disease; LIHC cis rs2455799 0.573 rs924753 chr3:15706124 C/T cg12698662 chr3:15914712 MIR563 -0.35 -6.5 -0.33 2.83e-10 Mean platelet volume; LIHC cis rs1552244 0.554 rs6762594 chr3:9995516 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -7.96 -0.4 2.63e-14 Alzheimer's disease; LIHC trans rs2727020 0.530 rs7113153 chr11:49457957 G/A cg15704280 chr7:45808275 SEPT13 -0.75 -11.11 -0.51 1.13e-24 Coronary artery disease; LIHC cis rs66573146 1.000 rs55672215 chr4:6970529 T/C cg00086871 chr4:6988644 TBC1D14 0.92 6.1 0.31 2.93e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs9309473 0.632 rs6706179 chr2:73578577 C/T cg20560298 chr2:73613845 ALMS1 -0.44 -6.96 -0.35 1.77e-11 Metabolite levels; LIHC cis rs7666738 0.830 rs1876192 chr4:98727555 T/C cg05340658 chr4:99064831 C4orf37 0.64 11.59 0.53 2.03e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs7945718 0.967 rs10831904 chr11:12760937 A/G cg25843174 chr11:12811716 TEAD1 0.37 8.41 0.41 1.1e-15 Educational attainment (years of education); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg06998038 chr14:65209844 PLEKHG3 0.44 6.45 0.33 3.79e-10 Longevity; LIHC cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg17971929 chr21:40555470 PSMG1 0.85 10.53 0.49 1.2e-22 Cognitive function; LIHC cis rs7572733 0.534 rs1401095 chr2:198779867 C/T cg00792783 chr2:198669748 PLCL1 -0.46 -6.75 -0.34 6.3e-11 Dermatomyositis; LIHC cis rs2067615 0.524 rs10467029 chr12:107078448 C/T cg15890332 chr12:107067104 RFX4 0.27 6.5 0.33 2.84e-10 Heart rate; LIHC cis rs1878931 0.582 rs27225 chr16:3428060 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.65 -8.22 -0.41 4.33e-15 Body mass index (adult); LIHC cis rs7520050 0.778 rs12404197 chr1:46232420 G/A cg03146154 chr1:46216737 IPP -0.48 -8.01 -0.4 1.83e-14 Red blood cell count;Reticulocyte count; LIHC cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2242116 0.761 rs6780601 chr3:46965856 A/G cg16586182 chr3:47516702 SCAP -0.4 -6.81 -0.35 4.37e-11 Birth weight; LIHC cis rs3806843 0.868 rs2262574 chr5:140123635 G/T cg26395211 chr5:140044315 WDR55 0.38 5.73 0.3 2.2e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg24879335 chr3:133465180 TF 0.29 6.55 0.33 2.05e-10 Iron status biomarkers; LIHC cis rs240764 0.746 rs240156 chr6:101063149 C/G cg09795085 chr6:101329169 ASCC3 0.5 6.78 0.34 5.17e-11 Neuroticism; LIHC cis rs2404602 0.647 rs11072610 chr15:76930805 C/A cg03037974 chr15:76606532 NA -0.6 -9.88 -0.47 2.04e-20 Blood metabolite levels; LIHC cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg25072359 chr17:41440525 NA 0.4 6.29 0.32 9.63e-10 Menopause (age at onset); LIHC cis rs1969363 0.509 rs8189633 chr12:38065155 C/G cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Morning vs. evening chronotype; LIHC cis rs2836950 0.501 rs4818019 chr21:40694456 T/A cg11890956 chr21:40555474 PSMG1 -0.41 -6.66 -0.34 1.08e-10 Menarche (age at onset); LIHC cis rs2806561 0.606 rs10917335 chr1:23294136 A/G cg12483005 chr1:23474871 LUZP1 0.42 6.34 0.32 7.36e-10 Height; LIHC cis rs4906332 0.901 rs4900575 chr14:103899169 G/C cg19000871 chr14:103996768 TRMT61A -0.46 -7.9 -0.39 3.81e-14 Coronary artery disease; LIHC cis rs1577917 0.771 rs7762321 chr6:86412146 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.55 0.33 2.11e-10 Response to antipsychotic treatment; LIHC cis rs2404602 0.735 rs1607015 chr15:76702429 C/T cg03037974 chr15:76606532 NA -0.64 -11.17 -0.52 6.59e-25 Blood metabolite levels; LIHC cis rs7659604 0.539 rs3217773 chr4:122739121 A/G cg20573242 chr4:122745356 CCNA2 0.51 7.52 0.38 4.93e-13 Type 2 diabetes; LIHC cis rs12815613 0.539 rs7300883 chr12:121459440 C/G cg02403541 chr12:121454288 C12orf43 -0.43 -6.44 -0.33 4.15e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg21724239 chr8:58056113 NA 0.44 5.94 0.31 7.09e-9 Developmental language disorder (linguistic errors); LIHC cis rs6570726 0.846 rs426874 chr6:145880630 A/C cg23711669 chr6:146136114 FBXO30 0.64 11.48 0.53 4.88e-26 Lobe attachment (rater-scored or self-reported); LIHC trans rs5756813 0.668 rs6000881 chr22:38154544 G/A cg19894588 chr14:64061835 NA 0.44 6.39 0.33 5.31e-10 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7119038 0.865 rs4936443 chr11:118740864 C/T cg19308663 chr11:118741387 NA -0.48 -6.29 -0.32 9.76e-10 Sjögren's syndrome; LIHC cis rs10832963 1.000 rs10832956 chr11:18645668 A/G cg09201001 chr11:18656081 SPTY2D1 0.94 17.6 0.69 7.76e-50 Breast cancer; LIHC cis rs12908161 0.853 rs12912342 chr15:85248216 T/C cg03959625 chr15:84868606 LOC388152 0.39 5.82 0.3 1.38e-8 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04571369 chr19:19749068 GMIP 0.4 6.15 0.32 2.15e-9 Pancreatic cancer; LIHC cis rs1775715 0.870 rs1755080 chr10:32255195 G/A cg14930904 chr10:32216787 ARHGAP12 0.4 7.02 0.35 1.21e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs921968 0.613 rs556497 chr2:219446477 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.32 0.32 8.27e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs17854409 0.764 rs12625513 chr20:61475661 G/A cg07645718 chr20:61493192 TCFL5 0.82 6.1 0.31 2.8e-9 Obesity-related traits; LIHC trans rs801193 1.000 rs2707845 chr7:66198798 C/T cg26939375 chr7:64535504 NA 0.42 6.82 0.35 4.26e-11 Aortic root size; LIHC cis rs7818688 0.697 rs74861094 chr8:95981385 A/G cg16049864 chr8:95962084 TP53INP1 0.61 6.69 0.34 9.39e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07682378 chr3:150128910 TSC22D2 0.39 6.28 0.32 1.05e-9 Cognitive function; LIHC cis rs6952808 0.862 rs4721135 chr7:1912222 A/G cg04267008 chr7:1944627 MAD1L1 -0.57 -8.8 -0.43 6.79e-17 Bipolar disorder and schizophrenia; LIHC cis rs11168351 0.927 rs11168342 chr12:48383797 G/T cg21466736 chr12:48725269 NA -0.57 -7.85 -0.39 5.57e-14 Bipolar disorder and schizophrenia; LIHC cis rs7726839 0.540 rs72703083 chr5:595365 C/T cg09021430 chr5:549028 NA -0.42 -8.36 -0.41 1.65e-15 Obesity-related traits; LIHC cis rs1008375 0.932 rs4698630 chr4:17614692 C/G cg16339924 chr4:17578868 LAP3 0.42 5.83 0.3 1.27e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.855 rs35666723 chr10:867346 A/G cg20503657 chr10:835505 NA 1.34 13.9 0.6 3.84e-35 Eosinophil percentage of granulocytes; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12927203 chr7:56032122 GBAS -0.5 -7.17 -0.36 4.73e-12 Pancreatic cancer; LIHC trans rs6594499 0.778 rs3806932 chr5:110405675 C/T cg23849483 chr19:15224544 SYDE1 -0.5 -6.04 -0.31 3.94e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2153535 0.580 rs5001324 chr6:8451604 A/T cg21535247 chr6:8435926 SLC35B3 0.63 8.27 0.41 3e-15 Motion sickness; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23674352 chr6:100016770 CCNC -0.5 -6.99 -0.35 1.46e-11 Pancreatic cancer; LIHC cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg12463550 chr7:65579703 CRCP -0.66 -6.83 -0.35 3.91e-11 Diabetic kidney disease; LIHC cis rs10503871 0.761 rs6997010 chr8:30365489 T/A cg26383811 chr8:30366931 RBPMS 0.42 7.46 0.37 7.27e-13 Metabolite levels (X-11787); LIHC cis rs4242434 0.757 rs7005025 chr8:22519815 G/T cg03733263 chr8:22462867 KIAA1967 0.69 11.39 0.52 1.02e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs801193 0.569 rs13226966 chr7:66233623 A/G cg11764359 chr7:65958608 NA 0.75 12.66 0.56 2.14e-30 Aortic root size; LIHC cis rs17685 0.712 rs7794454 chr7:75776010 A/G cg01364799 chr7:75623366 TMEM120A 0.4 6.09 0.31 3.12e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 0.866 rs1454491 chr3:40352647 C/G cg00656387 chr3:40428638 ENTPD3 0.38 5.95 0.31 6.7e-9 Renal cell carcinoma; LIHC cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg05025164 chr4:1340916 KIAA1530 0.76 11.82 0.54 2.82e-27 Longevity; LIHC cis rs12497850 0.897 rs9681717 chr3:48872998 A/G cg06212747 chr3:49208901 KLHDC8B 0.55 7.07 0.36 8.98e-12 Parkinson's disease; LIHC cis rs9467773 0.506 rs9393709 chr6:26365147 C/T cg14345882 chr6:26364793 BTN3A2 0.34 5.74 0.3 2.04e-8 Intelligence (multi-trait analysis); LIHC cis rs11673344 0.868 rs1047333 chr19:37642165 G/A cg27390819 chr19:37464633 NA -0.53 -6.3 -0.32 8.94e-10 Obesity-related traits; LIHC cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs62064224 0.593 rs916663 chr17:30835833 A/C cg25809561 chr17:30822961 MYO1D -0.46 -7.24 -0.36 3.06e-12 Schizophrenia; LIHC cis rs477895 0.838 rs35090903 chr11:64000598 C/T cg05555928 chr11:63887634 MACROD1 0.46 6.02 0.31 4.41e-9 Mean platelet volume; LIHC cis rs11958404 0.858 rs72818142 chr5:157474934 C/T cg05962755 chr5:157440814 NA 1.0 11.73 0.54 6.22e-27 IgG glycosylation; LIHC trans rs11165623 0.740 rs11165638 chr1:96921357 C/A cg10631902 chr5:14652156 NA -0.34 -8.5 -0.42 5.84e-16 Hip circumference;Waist circumference; LIHC trans rs9929218 0.529 rs17715450 chr16:68729785 C/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.85 18.64 0.71 5.42e-54 Colorectal cancer; LIHC cis rs1843834 0.734 rs1908251 chr2:225487865 T/C cg22455342 chr2:225449267 CUL3 0.46 6.2 0.32 1.64e-9 IgE levels in asthmatics (D.p. specific); LIHC trans rs916888 0.773 rs199534 chr17:44824213 T/G cg16836995 chr17:43662488 NA -0.76 -7.82 -0.39 6.7e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00852675 chr7:150105086 LOC728743 0.41 6.31 0.32 8.4e-10 Bilirubin levels; LIHC cis rs7107174 1.000 rs2512550 chr11:77943848 C/T cg02023728 chr11:77925099 USP35 0.46 8.69 0.43 1.58e-16 Testicular germ cell tumor; LIHC cis rs2576037 0.583 rs9954336 chr18:44465945 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 11.02 0.51 2.26e-24 Personality dimensions; LIHC cis rs7927592 0.956 rs10896337 chr11:68284236 T/C cg01657329 chr11:68192670 LRP5 -0.47 -6.09 -0.31 3.12e-9 Total body bone mineral density; LIHC cis rs7927771 1.000 rs4752857 chr11:47655752 C/T cg18512352 chr11:47633146 NA -0.25 -5.89 -0.3 9.48e-9 Subjective well-being; LIHC cis rs926392 0.666 rs35166252 chr20:37695601 C/T cg16355469 chr20:37678765 NA 0.48 6.99 0.35 1.43e-11 Dialysis-related mortality; LIHC cis rs17750015 0.733 rs12454362 chr18:54396186 G/A cg18434998 chr18:54306185 TXNL1 -0.48 -6.64 -0.34 1.2e-10 Depression and alcohol dependence; LIHC cis rs12477438 0.520 rs6756650 chr2:99801800 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.66 0.65 4.89e-42 Chronic sinus infection; LIHC cis rs35306767 0.953 rs1539174 chr10:974870 C/G cg20503657 chr10:835505 NA 0.88 10.35 0.49 5.19e-22 Eosinophil percentage of granulocytes; LIHC cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg25072359 chr17:41440525 NA 0.38 6.02 0.31 4.56e-9 Menopause (age at onset); LIHC cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 7.43 0.37 9.02e-13 Platelet count; LIHC cis rs636291 0.517 rs2781233 chr1:10529194 T/C cg17425144 chr1:10567563 PEX14 0.52 10.11 0.48 3.46e-21 Prostate cancer; LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg12379764 chr21:47803548 PCNT 0.54 8.09 0.4 1.02e-14 Testicular germ cell tumor; LIHC cis rs13191362 1.000 rs34398656 chr6:162999612 G/T cg06582575 chr6:163149167 PACRG;PARK2 0.6 5.79 0.3 1.61e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs36051895 0.589 rs10122037 chr9:5192874 A/G cg02405213 chr9:5042618 JAK2 0.68 11.49 0.53 4.61e-26 Pediatric autoimmune diseases; LIHC cis rs67478160 0.584 rs12433009 chr14:104196405 C/G cg08213375 chr14:104286397 PPP1R13B 0.49 9.3 0.45 1.68e-18 Schizophrenia; LIHC cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg06466757 chr4:1255808 NA 0.34 5.75 0.3 1.96e-8 Obesity-related traits; LIHC trans rs7246657 0.943 rs10413602 chr19:37891492 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg05564831 chr3:52568323 NT5DC2 0.36 5.89 0.3 9.25e-9 Bipolar disorder; LIHC cis rs7249142 0.549 rs2239369 chr19:19292405 A/T cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B 0.42 7.15 0.36 5.3e-12 IgG glycosylation; LIHC cis rs826838 0.616 rs2200605 chr12:38624088 G/A cg26384229 chr12:38710491 ALG10B 0.43 6.49 0.33 2.93e-10 Heart rate; LIHC cis rs7107174 1.000 rs10899474 chr11:78043636 T/C cg02023728 chr11:77925099 USP35 0.48 9.02 0.44 1.4e-17 Testicular germ cell tumor; LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg03188948 chr7:1209495 NA 0.43 5.95 0.31 6.57e-9 Longevity;Endometriosis; LIHC cis rs6867032 0.527 rs4246752 chr5:1975575 T/A cg26168224 chr5:2018326 NA -0.26 -6.05 -0.31 3.79e-9 Gut microbiome composition (winter); LIHC cis rs2645424 0.530 rs1293303 chr8:11720227 C/G cg21281001 chr8:11725306 CTSB -0.48 -7.4 -0.37 1.04e-12 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); LIHC cis rs2257205 0.667 rs7211439 chr17:56847832 A/T cg12560992 chr17:57184187 TRIM37 0.68 7.44 0.37 8.24e-13 Pancreatic cancer; LIHC trans rs1005277 0.579 rs116912400 chr10:38479207 G/T cg27523141 chr10:43048294 ZNF37B 0.38 6.34 0.32 7.24e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6120849 0.754 rs6120797 chr20:33606002 G/A cg24642439 chr20:33292090 TP53INP2 0.65 7.15 0.36 5.14e-12 Protein C levels; LIHC cis rs939574 0.790 rs72955452 chr2:220101783 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.92 6.47 0.33 3.39e-10 Platelet distribution width; LIHC trans rs66573146 0.808 rs55942328 chr4:6990960 T/G cg07817883 chr1:32538562 TMEM39B 1.17 9.23 0.45 2.83e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs875971 0.929 rs778712 chr7:65849978 C/T cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs992157 0.764 rs2382827 chr2:219184387 G/A cg00012203 chr2:219082015 ARPC2 0.75 10.52 0.49 1.33e-22 Colorectal cancer; LIHC cis rs11931598 0.513 rs3857170 chr4:7003366 A/T cg26116260 chr4:7069785 GRPEL1 0.52 8.88 0.43 3.94e-17 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs2115630 0.645 rs3825878 chr15:85174755 C/T cg11189052 chr15:85197271 WDR73 -0.53 -8.23 -0.41 4e-15 P wave terminal force; LIHC cis rs6088580 0.634 rs1205344 chr20:32918298 G/A cg08999081 chr20:33150536 PIGU -0.66 -12.59 -0.56 4e-30 Glomerular filtration rate (creatinine); LIHC cis rs17685 0.712 rs28506984 chr7:75763484 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs992157 0.835 rs7585702 chr2:219146607 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.16 -0.55 1.65e-28 Colorectal cancer; LIHC trans rs4843747 0.573 rs7499959 chr16:88110422 C/G cg09572067 chr16:29127029 RRN3P2 0.47 7.55 0.38 4.01e-13 Menopause (age at onset); LIHC trans rs801193 1.000 rs2707856 chr7:66211010 A/T cg26939375 chr7:64535504 NA 0.43 6.9 0.35 2.56e-11 Aortic root size; LIHC cis rs5769765 0.908 rs9616390 chr22:50314289 G/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.36 -0.49 4.56e-22 Schizophrenia; LIHC cis rs2019216 0.872 rs6565384 chr17:21897456 T/C cg22648282 chr17:21454238 C17orf51 -0.34 -5.82 -0.3 1.33e-8 Pelvic organ prolapse; LIHC cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg13047869 chr3:10149882 C3orf24 0.55 6.93 0.35 2.08e-11 Alzheimer's disease; LIHC cis rs12986413 0.624 rs2108825 chr19:2136515 T/C cg09261902 chr19:2140048 AP3D1 0.4 6.83 0.35 3.92e-11 Height; LIHC cis rs3753275 0.690 rs2399144 chr1:8539269 C/A cg20416874 chr1:8611966 RERE -0.47 -5.73 -0.3 2.25e-8 Educational attainment; LIHC cis rs9640161 0.783 rs1132261 chr7:150059987 G/A cg10018233 chr7:150070692 REPIN1 0.67 12.36 0.56 2.97e-29 Blood protein levels;Circulating chemerin levels; LIHC cis rs778371 0.723 rs34707169 chr2:233699459 C/T cg08000102 chr2:233561755 GIGYF2 -0.77 -9.37 -0.45 1.01e-18 Schizophrenia; LIHC cis rs7412746 0.658 rs72704685 chr1:150897687 C/G cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs11608355 0.672 rs9943689 chr12:109890339 G/A cg04065206 chr12:109973212 UBE3B -0.58 -6.58 -0.34 1.73e-10 Neuroticism; LIHC cis rs72781680 0.898 rs12619592 chr2:23971415 C/A cg08917208 chr2:24149416 ATAD2B 0.83 7.63 0.38 2.42e-13 Lymphocyte counts; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg16512924 chr15:28394682 HERC2 0.37 6.26 0.32 1.13e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs743757 1.000 rs2298955 chr3:50431194 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 -0.46 -6.43 -0.33 4.26e-10 Diastolic blood pressure; LIHC cis rs2730245 0.550 rs2788478 chr7:158672619 A/G cg24397884 chr7:158709396 WDR60 0.43 6.3 0.32 9.15e-10 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10198271 chr20:55966838 RBM38 0.5 6.43 0.33 4.37e-10 Lung function (FEV1/FVC); LIHC cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg15691649 chr6:25882328 NA -0.53 -7.68 -0.38 1.67e-13 Blood metabolite levels; LIHC cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg11764359 chr7:65958608 NA -0.59 -6.17 -0.32 1.94e-9 Diabetic kidney disease; LIHC cis rs11676348 0.714 rs4674254 chr2:218986077 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.44 -6.15 -0.32 2.21e-9 Ulcerative colitis; LIHC cis rs3823572 0.526 rs2971966 chr7:133642559 A/G cg03336402 chr7:133662267 EXOC4 -0.46 -5.72 -0.3 2.3e-8 Intelligence (multi-trait analysis); LIHC cis rs1707322 1.000 rs7547189 chr1:46319514 C/A cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2408955 0.522 rs4760679 chr12:48461635 G/T cg21466736 chr12:48725269 NA 0.63 8.99 0.44 1.69e-17 Glycated hemoglobin levels; LIHC cis rs7149337 0.752 rs8021773 chr14:51691528 C/T cg23942311 chr14:51606299 NA 0.36 7.54 0.38 4.18e-13 Cancer; LIHC cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg13012494 chr21:47604986 C21orf56 0.39 6.01 0.31 4.81e-9 Testicular germ cell tumor; LIHC cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg08888203 chr3:10149979 C3orf24 0.53 6.43 0.33 4.35e-10 Alzheimer's disease; LIHC cis rs826838 1.000 rs11609286 chr12:38875511 A/G cg26384229 chr12:38710491 ALG10B -0.96 -13.14 -0.58 3.26e-32 Heart rate; LIHC cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg00343986 chr7:65444356 GUSB -0.45 -6.28 -0.32 1.05e-9 Calcium levels; LIHC trans rs208520 0.690 rs4386800 chr6:66755242 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.86 0.43 4.39e-17 Exhaled nitric oxide output; LIHC cis rs8180040 0.966 rs57346147 chr3:47410564 C/G cg16586182 chr3:47516702 SCAP 0.61 11.58 0.53 2.11e-26 Colorectal cancer; LIHC cis rs6121246 0.909 rs7354225 chr20:30296881 C/T cg13852791 chr20:30311386 BCL2L1 0.89 8.61 0.42 2.8e-16 Mean corpuscular hemoglobin; LIHC cis rs7843479 0.601 rs2306646 chr8:21846586 C/G cg17168535 chr8:21777572 XPO7 0.59 10.06 0.48 4.97e-21 Mean corpuscular volume; LIHC cis rs796364 0.806 rs203766 chr2:200902672 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.78 -8.65 -0.42 1.97e-16 Schizophrenia; LIHC cis rs8016982 0.855 rs10149681 chr14:81686319 G/A cg01989461 chr14:81687754 GTF2A1 0.56 11.19 0.52 5.64e-25 Schizophrenia; LIHC cis rs9640161 0.659 rs7788316 chr7:150013995 A/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.45 -7.89 -0.39 4.14e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs17152411 1.000 rs17152377 chr10:126592852 T/G cg07906193 chr10:126599966 NA 0.46 7.14 0.36 5.71e-12 Height; LIHC cis rs2228479 0.850 rs17233664 chr16:89810628 C/T cg04013166 chr16:89971882 TCF25 0.49 6.08 0.31 3.24e-9 Skin colour saturation; LIHC cis rs11711311 1.000 rs9288983 chr3:113488699 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.03 -0.36 1.1e-11 IgG glycosylation; LIHC cis rs1008375 0.866 rs2109518 chr4:17572162 G/A cg16339924 chr4:17578868 LAP3 0.43 5.73 0.3 2.17e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9916302 0.706 rs12947506 chr17:37707592 A/G cg07936489 chr17:37558343 FBXL20 -0.82 -11.43 -0.53 7.89e-26 Glomerular filtration rate (creatinine); LIHC cis rs7618501 0.933 rs6809431 chr3:49804119 A/G cg21467203 chr3:49911342 NA -0.41 -7.07 -0.36 9e-12 Intelligence (multi-trait analysis); LIHC trans rs4332037 0.802 rs73048106 chr7:1929019 G/T cg11693508 chr17:37793320 STARD3 0.7 7.13 0.36 5.91e-12 Bipolar disorder; LIHC cis rs1348850 0.526 rs10803912 chr2:178407176 A/C cg27490568 chr2:178487706 NA -0.87 -9.81 -0.47 3.64e-20 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10504229 0.609 rs66477547 chr8:58105763 A/C cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.83e-9 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.771 rs9450290 chr6:86233397 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 8.17 0.4 5.97e-15 Response to antipsychotic treatment; LIHC cis rs1707322 0.721 rs12049027 chr1:46118184 A/T cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs62244186 0.715 rs11130032 chr3:44704083 G/A cg25364880 chr3:44379878 C3orf23 0.55 7.54 0.38 4.19e-13 Depressive symptoms; LIHC cis rs2637266 0.783 rs2583070 chr10:78518555 C/T cg18941641 chr10:78392320 NA 0.27 5.84 0.3 1.22e-8 Pulmonary function; LIHC cis rs4808199 0.948 rs2023883 chr19:19405480 G/A cg03709012 chr19:19516395 GATAD2A 0.97 15.56 0.64 1.13e-41 Nonalcoholic fatty liver disease; LIHC cis rs858239 0.600 rs28499396 chr7:23124098 A/G cg23682824 chr7:23144976 KLHL7 0.41 6.23 0.32 1.39e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs45544231 0.569 rs9933556 chr16:52548302 C/T cg09051775 chr16:52580266 TOX3 -0.32 -5.77 -0.3 1.81e-8 Restless legs syndrome; LIHC cis rs2242116 0.796 rs7645278 chr3:46974100 A/C cg02527881 chr3:46936655 PTH1R -0.45 -9.11 -0.44 7.33e-18 Birth weight; LIHC cis rs2806561 0.765 rs9426692 chr1:23508426 C/T cg12483005 chr1:23474871 LUZP1 0.46 7.33 0.37 1.66e-12 Height; LIHC cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg00166722 chr3:10149974 C3orf24 0.53 5.99 0.31 5.29e-9 Alzheimer's disease; LIHC cis rs9911578 0.935 rs6503878 chr17:56884581 T/G cg12560992 chr17:57184187 TRIM37 0.97 17.46 0.69 2.94e-49 Intelligence (multi-trait analysis); LIHC cis rs17685 0.712 rs7794454 chr7:75776010 A/G cg16684958 chr7:75615977 POR -0.39 -6.58 -0.34 1.78e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4517514 0.509 rs11018875 chr11:89876356 T/C cg05041596 chr11:89867385 NAALAD2 0.41 6.51 0.33 2.63e-10 Trans fatty acid levels; LIHC cis rs9581857 0.556 rs1885990 chr13:28040502 C/T cg22138327 chr13:27999177 GTF3A 0.45 6.74 0.34 6.66e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs7959452 0.640 rs12370042 chr12:69692420 C/G cg22834771 chr12:69754056 YEATS4 -0.47 -8.04 -0.4 1.53e-14 Blood protein levels; LIHC cis rs1348850 0.757 rs4893954 chr2:178340520 T/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.86 13.18 0.58 2.34e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9378688 0.654 rs2505657 chr6:2331510 T/C cg12303981 chr6:2244766 GMDS -0.45 -6.06 -0.31 3.69e-9 Caudate nucleus volume; LIHC cis rs67981189 0.574 rs2810118 chr14:71388575 A/G cg15816911 chr14:71606274 NA -0.4 -6.34 -0.32 7.09e-10 Schizophrenia; LIHC cis rs67311347 1.000 rs9874006 chr3:40471596 G/A cg13409248 chr3:40428643 ENTPD3 0.41 6.9 0.35 2.58e-11 Renal cell carcinoma; LIHC cis rs2236918 1.000 rs851782 chr1:242033783 A/G cg17736920 chr1:242011382 EXO1 0.61 8.79 0.43 7.16e-17 Menopause (age at onset); LIHC cis rs8180040 0.764 rs12630534 chr3:47001043 T/C cg02527881 chr3:46936655 PTH1R -0.35 -7.02 -0.36 1.17e-11 Colorectal cancer; LIHC cis rs9467773 0.901 rs1407045 chr6:26476155 A/G cg09904177 chr6:26538194 HMGN4 0.55 10.24 0.48 1.19e-21 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.816 rs13059144 chr3:10010197 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs10744422 1.000 rs7972447 chr12:123354545 C/G cg22842854 chr12:123319900 HIP1R -0.61 -7.5 -0.38 5.44e-13 Schizophrenia; LIHC cis rs9457247 0.765 rs9459838 chr6:167426599 C/G cg07741184 chr6:167504864 NA 0.32 7.36 0.37 1.42e-12 Crohn's disease; LIHC cis rs11252926 0.650 rs11252902 chr10:562796 G/T cg09445902 chr10:555545 DIP2C -0.39 -6.21 -0.32 1.49e-9 Psychosis in Alzheimer's disease; LIHC cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg20011983 chr2:74347215 NA -0.41 -6.18 -0.32 1.77e-9 Gestational age at birth (maternal effect); LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg18306943 chr3:40428807 ENTPD3 0.42 7.45 0.37 7.47e-13 Renal cell carcinoma; LIHC cis rs116095464 0.558 rs10059907 chr5:205360 G/C cg22496380 chr5:211416 CCDC127 -1.19 -10.49 -0.49 1.66e-22 Breast cancer; LIHC cis rs7223966 1.000 rs7220892 chr17:61908316 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.54 6.52 0.33 2.48e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs2230307 0.536 rs473759 chr1:100557282 C/G cg24955406 chr1:100503596 HIAT1 0.6 5.99 0.31 5.44e-9 Carotid intima media thickness; LIHC cis rs637571 0.510 rs10896052 chr11:65579600 C/A cg04055107 chr11:65626734 MUS81;CFL1 -0.46 -6.64 -0.34 1.24e-10 Eosinophil percentage of white cells; LIHC cis rs67311347 0.911 rs9849224 chr3:40392562 T/C cg13409248 chr3:40428643 ENTPD3 0.4 6.64 0.34 1.2e-10 Renal cell carcinoma; LIHC cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg07414643 chr4:187882934 NA 0.23 5.97 0.31 6.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6582630 0.519 rs11514078 chr12:38408817 G/C cg26384229 chr12:38710491 ALG10B 0.59 8.08 0.4 1.11e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg26119090 chr2:26468346 HADHA;HADHB -1.14 -17.46 -0.69 2.95e-49 Gut microbiome composition (summer); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24063092 chr5:65018104 NLN;SGTB 0.46 6.51 0.33 2.74e-10 Lung function (FEV1/FVC); LIHC cis rs748404 0.578 rs4547312 chr15:43632138 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.56 10.15 0.48 2.43e-21 Lung cancer; LIHC cis rs116095464 0.867 rs7726582 chr5:215349 C/G cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs2637266 0.626 rs846617 chr10:78546881 A/G cg18941641 chr10:78392320 NA 0.29 6.25 0.32 1.24e-9 Pulmonary function; LIHC cis rs10883723 0.810 rs3740406 chr10:104272789 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs238295 0.766 rs6038204 chr20:5549071 T/A cg24001556 chr20:5591874 RP5-1022P6.2 -0.53 -7.19 -0.36 4.16e-12 Occipital cortical area (total cortical area interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27449836 chr1:179846920 TOR1AIP2 -0.48 -6.73 -0.34 7.3e-11 Pancreatic cancer; LIHC cis rs2404602 0.647 rs11072620 chr15:77048770 T/A cg03037974 chr15:76606532 NA -0.62 -10.45 -0.49 2.24e-22 Blood metabolite levels; LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg07092213 chr7:1199455 ZFAND2A -0.48 -7.32 -0.37 1.77e-12 Longevity;Endometriosis; LIHC cis rs9534288 0.716 rs2573304 chr13:46514642 C/T cg15192986 chr13:46630673 CPB2 0.55 7.73 0.39 1.21e-13 Blood protein levels; LIHC cis rs1355223 0.902 rs2185700 chr11:34724204 G/A cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.37 -0.33 5.97e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs67311347 1.000 rs11129876 chr3:40401636 C/T cg13409248 chr3:40428643 ENTPD3 -0.38 -6.36 -0.33 6.59e-10 Renal cell carcinoma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11442381 chr3:52312806 WDR82 0.51 6.49 0.33 2.99e-10 Lung function (FEV1/FVC); LIHC cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 8.86 0.43 4.51e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.86e-9 Total body bone mineral density; LIHC cis rs2075371 0.829 rs1993058 chr7:133930361 G/A cg20476274 chr7:133979776 SLC35B4 0.65 8.74 0.43 1.08e-16 Mean platelet volume; LIHC cis rs9790314 0.663 rs778657 chr3:160719577 C/A cg03342759 chr3:160939853 NMD3 -0.58 -8.0 -0.4 1.98e-14 Morning vs. evening chronotype; LIHC cis rs975210 0.652 rs4777230 chr15:70365762 A/G cg01666796 chr15:70364327 TLE3 -0.6 -7.57 -0.38 3.55e-13 Height;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs78545713 1.000 rs114970164 chr6:26241993 G/C cg16070018 chr6:26224392 HIST1H3E 0.68 7.25 0.37 2.75e-12 Iron status biomarkers (total iron binding capacity); LIHC cis rs992157 0.560 rs1514132 chr2:219084082 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.05 -0.55 4.04e-28 Colorectal cancer; LIHC cis rs929354 0.742 rs1182396 chr7:157031831 A/C cg05182265 chr7:156933206 UBE3C 0.32 6.03 0.31 4.26e-9 Body mass index; LIHC cis rs28655083 0.828 rs9938028 chr16:77127830 A/C cg09454613 chr16:77233327 SYCE1L;MON1B -0.37 -5.83 -0.3 1.31e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2228479 0.850 rs2190808 chr16:89840856 C/T cg06558623 chr16:89946397 TCF25 0.84 11.74 0.54 5.79e-27 Skin colour saturation; LIHC cis rs11122272 0.735 rs971534 chr1:231521971 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs763014 1.000 rs2269558 chr16:682250 C/T cg04709771 chr16:646395 RAB40C 0.46 8.19 0.41 5.1e-15 Height; LIHC cis rs9311474 1.000 rs1060330 chr3:52288945 T/C cg18404041 chr3:52824283 ITIH1 -0.35 -5.78 -0.3 1.69e-8 Electroencephalogram traits; LIHC cis rs7772486 0.846 rs866473 chr6:146353414 A/C cg05347473 chr6:146136440 FBXO30 0.36 5.88 0.3 9.7e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2976388 0.609 rs2572899 chr8:143785549 A/G cg06565975 chr8:143823917 SLURP1 0.34 6.57 0.33 1.84e-10 Urinary tract infection frequency; LIHC cis rs10463316 0.862 rs7720582 chr5:150776502 C/T cg03212797 chr5:150827313 SLC36A1 0.45 6.89 0.35 2.71e-11 Metabolite levels (Pyroglutamine); LIHC cis rs6963495 0.745 rs55906043 chr7:105165367 T/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2976388 0.573 rs1529865 chr8:143789171 C/T cg13446199 chr8:143762866 PSCA -0.2 -5.78 -0.3 1.71e-8 Urinary tract infection frequency; LIHC cis rs807669 0.868 rs2800973 chr22:19168616 A/G cg02655711 chr22:19163373 SLC25A1 0.71 10.98 0.51 3.07e-24 Metabolite levels; LIHC cis rs7659604 0.702 rs6826506 chr4:122710865 T/G cg20573242 chr4:122745356 CCNA2 0.52 7.55 0.38 4.04e-13 Type 2 diabetes; LIHC cis rs6835098 1.000 rs10031414 chr4:174084953 A/C cg27433088 chr4:174089019 GALNT7 0.39 7.18 0.36 4.26e-12 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs12701220 0.894 rs12701348 chr7:1039457 C/T cg04498913 chr7:1135747 C7orf50 0.38 6.06 0.31 3.52e-9 Bronchopulmonary dysplasia; LIHC cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.57 8.59 0.42 3.06e-16 Height; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.16 0.55 1.61e-28 Prudent dietary pattern; LIHC cis rs644799 0.763 rs2950521 chr11:95536870 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.39 0.68 5.86e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7131987 0.650 rs7973786 chr12:29462744 C/T cg05697976 chr12:29376483 FAR2 0.28 5.76 0.3 1.83e-8 QT interval; LIHC cis rs6840360 0.901 rs4696293 chr4:152707380 C/T cg22705602 chr4:152727874 NA 0.31 6.82 0.35 4.02e-11 Intelligence (multi-trait analysis); LIHC trans rs10506458 0.915 rs2013050 chr12:63394310 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.75 -10.69 -0.5 3.33e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs9916302 0.904 rs2338755 chr17:37419317 C/T cg07936489 chr17:37558343 FBXL20 0.84 13.92 0.6 3.4000000000000003e-35 Glomerular filtration rate (creatinine); LIHC cis rs4388979 0.595 rs9668456 chr12:109493428 C/T cg03220751 chr12:109490328 USP30 0.6 9.41 0.45 7.4e-19 Plateletcrit;Platelet count; LIHC cis rs8078723 0.714 rs2241244 chr17:38153554 G/C cg17467752 chr17:38218738 THRA -0.61 -10.36 -0.49 4.6e-22 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs4820294 0.669 rs1894532 chr22:38059750 T/C cg26138144 chr22:38071188 LGALS1 0.41 7.42 0.37 9.25e-13 Fat distribution (HIV); LIHC trans rs208515 0.525 rs9453538 chr6:66668508 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.79 8.91 0.43 3.18e-17 Exhaled nitric oxide levels; LIHC cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg18252515 chr7:66147081 NA -1.24 -15.85 -0.65 7.92e-43 Diabetic kidney disease; LIHC trans rs2727020 0.636 rs11040368 chr11:49453602 C/A cg18944383 chr4:111397179 ENPEP 0.25 6.25 0.32 1.22e-9 Coronary artery disease; LIHC cis rs9326248 0.954 rs10790177 chr11:117048417 A/G cg01368799 chr11:117014884 PAFAH1B2 0.42 6.0 0.31 4.97e-9 Blood protein levels; LIHC cis rs7917772 0.536 rs17783771 chr10:104410736 C/T cg22532475 chr10:104410764 TRIM8 -0.4 -6.74 -0.34 6.75e-11 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg11494091 chr17:61959527 GH2 0.36 6.03 0.31 4.26e-9 Height; LIHC cis rs2067615 0.542 rs4433659 chr12:107082496 G/T cg15890332 chr12:107067104 RFX4 0.26 6.23 0.32 1.39e-9 Heart rate; LIHC cis rs8016982 0.651 rs1885601 chr14:81641210 C/T cg01989461 chr14:81687754 GTF2A1 0.72 14.53 0.62 1.34e-37 Schizophrenia; LIHC cis rs2839186 0.559 rs2277826 chr21:47639492 C/G cg12516959 chr21:47718080 NA 0.4 6.42 0.33 4.59e-10 Testicular germ cell tumor; LIHC cis rs25645 0.792 rs8077456 chr17:38128765 C/G cg17344932 chr17:38183730 MED24;SNORD124 0.71 13.03 0.58 8.72e-32 Myeloid white cell count; LIHC trans rs7693389 0.925 rs4376200 chr4:58463119 T/G cg13593275 chr9:128777788 NA 0.56 6.11 0.31 2.75e-9 Diisocyanate-induced asthma; LIHC cis rs12744310 0.887 rs12045979 chr1:41809477 A/G cg03962019 chr1:41807865 NA 0.4 6.32 0.32 8e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6088580 0.543 rs13042351 chr20:33238573 G/A cg07148914 chr20:33460835 GGT7 -0.5 -7.1 -0.36 7.36e-12 Glomerular filtration rate (creatinine); LIHC cis rs13108904 0.557 rs1250097 chr4:1238338 C/T cg05025164 chr4:1340916 KIAA1530 -0.66 -9.93 -0.47 1.36e-20 Obesity-related traits; LIHC trans rs1005277 0.522 rs1208684 chr10:38093936 G/A cg27523141 chr10:43048294 ZNF37B 0.39 6.74 0.34 6.92e-11 Extrinsic epigenetic age acceleration; LIHC trans rs61931739 0.500 rs10772163 chr12:34532950 T/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs17685 0.736 rs4732594 chr7:75753273 T/C cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2979489 0.838 rs2979513 chr8:30397925 G/C cg26383811 chr8:30366931 RBPMS -0.72 -11.93 -0.54 1.14e-27 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs12079745 0.793 rs10919098 chr1:169189422 T/A cg09363564 chr1:169337483 NME7;BLZF1 -0.65 -6.13 -0.31 2.39e-9 QT interval; LIHC cis rs79419269 0.673 rs2792430 chr7:150926360 A/G cg01623806 chr7:150929509 CHPF2 -0.56 -5.87 -0.3 1.03e-8 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs727563 0.594 rs132807 chr22:42071584 T/C cg06634786 chr22:41940651 POLR3H 0.71 7.31 0.37 1.95e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs738322 0.511 rs2267371 chr22:38577119 T/G cg25457927 chr22:38595422 NA -0.38 -8.78 -0.43 8e-17 Cutaneous nevi; LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg09417038 chr21:47716443 C21orf57 -0.46 -7.05 -0.36 1.01e-11 Testicular germ cell tumor; LIHC cis rs9457247 0.967 rs2149084 chr6:167370988 G/C cg12798992 chr6:167411361 FGFR1OP -0.61 -9.81 -0.47 3.56e-20 Crohn's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17451422 chr2:61293253 KIAA1841 -0.52 -6.05 -0.31 3.75e-9 Systolic blood pressure; LIHC cis rs9534288 0.762 rs1571053 chr13:46554854 G/A cg15192986 chr13:46630673 CPB2 -0.54 -8.41 -0.41 1.15e-15 Blood protein levels; LIHC cis rs1008375 0.966 rs28441502 chr4:17598384 G/A cg16339924 chr4:17578868 LAP3 0.46 6.32 0.32 8.1e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4919087 0.923 rs11189038 chr10:98974765 A/T cg25902810 chr10:99078978 FRAT1 0.63 9.02 0.44 1.4e-17 Monocyte count; LIHC cis rs7044106 0.762 rs7044226 chr9:123466328 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.47 0.53 5.43e-26 Hip circumference adjusted for BMI; LIHC trans rs1005277 0.579 rs2505197 chr10:38393310 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4819052 0.885 rs9980676 chr21:46665430 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.62 0.53 1.61e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1538970 0.816 rs34673142 chr1:45985561 G/A cg05343316 chr1:45956843 TESK2 0.6 8.42 0.41 1.02e-15 Platelet count; LIHC cis rs10870270 1.000 rs10870292 chr10:133770782 G/C cg08754478 chr10:133766260 PPP2R2D -0.53 -7.72 -0.39 1.27e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs12134245 0.742 rs17501381 chr1:92003919 A/G cg07090678 chr1:91966139 CDC7 0.48 6.44 0.33 4.03e-10 Breast cancer; LIHC cis rs12478296 0.892 rs60042638 chr2:243038707 G/A cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.1e-27 Obesity-related traits; LIHC cis rs6882046 0.513 rs2431391 chr5:88046590 C/T cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs7953508 0.636 rs10859535 chr12:93979892 A/G cg18151635 chr12:93972918 NA -0.47 -7.24 -0.36 2.97e-12 Pubertal anthropometrics; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg26668828 chr6:292823 DUSP22 -0.62 -8.64 -0.42 2.18e-16 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18247177 chr17:7745472 KDM6B 0.44 6.3 0.32 9.13e-10 Pancreatic cancer; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg23800573 chr21:45114399 RRP1B 0.44 6.97 0.35 1.67e-11 Immature fraction of reticulocytes; LIHC cis rs7551222 0.752 rs4245736 chr1:204486205 G/C cg20240347 chr1:204465584 NA -0.36 -7.61 -0.38 2.75e-13 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19853194 chr18:9913725 VAPA 0.47 7.57 0.38 3.45e-13 Pancreatic cancer; LIHC cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg03060546 chr3:49711283 APEH -0.39 -5.95 -0.31 6.81e-9 Menarche (age at onset); LIHC cis rs6746896 0.959 rs2271893 chr2:97405440 G/A cg26665480 chr2:98280029 ACTR1B 0.44 5.73 0.3 2.16e-8 Bipolar disorder; LIHC cis rs6500602 0.727 rs12443748 chr16:4541831 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 5.86 0.3 1.08e-8 Schizophrenia; LIHC cis rs9503598 1.000 rs9503598 chr6:3446263 A/G cg00476032 chr6:3446245 SLC22A23 -0.46 -9.33 -0.45 1.4e-18 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg25072359 chr17:41440525 NA 0.36 5.76 0.3 1.89e-8 Menopause (age at onset); LIHC cis rs5769765 0.773 rs9616751 chr22:50222236 T/G cg09182678 chr22:50328711 NA -0.46 -5.93 -0.31 7.32e-9 Schizophrenia; LIHC cis rs10733682 0.659 rs13292976 chr9:129467340 C/T cg00232160 chr9:129468157 NA 0.38 6.59 0.34 1.68e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg19318889 chr4:1322082 MAEA 0.43 5.95 0.31 6.65e-9 Obesity-related traits; LIHC cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg24675658 chr1:53192096 ZYG11B -0.57 -8.77 -0.43 8.43e-17 Monocyte count; LIHC cis rs12472274 0.646 rs11688732 chr2:239096622 G/T cg17459225 chr2:239074497 NA 0.72 11.27 0.52 2.97e-25 Phospholipid levels (plasma); LIHC cis rs9814567 1.000 rs1498718 chr3:134205920 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.37 -0.56 2.66e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9814567 1.000 rs10935120 chr3:134233092 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.38 5.76 0.3 1.92e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6450176 1.000 rs10805455 chr5:53302302 T/G ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs17401966 0.964 rs2027331 chr1:10276718 C/T cg15208524 chr1:10270712 KIF1B 0.44 6.37 0.33 6e-10 Hepatocellular carcinoma; LIHC cis rs7107174 1.000 rs2510041 chr11:77945284 G/A cg02023728 chr11:77925099 USP35 0.44 8.49 0.42 6.59e-16 Testicular germ cell tumor; LIHC cis rs3749237 0.576 rs3877784 chr3:49539417 C/T cg06212747 chr3:49208901 KLHDC8B 0.48 6.2 0.32 1.66e-9 Resting heart rate; LIHC cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg00656387 chr3:40428638 ENTPD3 0.48 7.93 0.39 3.13e-14 Renal cell carcinoma; LIHC cis rs10792665 0.934 rs10898060 chr11:82660037 A/G cg24227371 chr11:82718527 RAB30 -0.31 -7.24 -0.36 2.97e-12 Obesity-related traits; LIHC cis rs67460515 0.892 rs4856703 chr3:161047720 G/T cg03342759 chr3:160939853 NMD3 -0.62 -9.26 -0.45 2.31e-18 Parkinson's disease; LIHC cis rs600806 0.751 rs1933182 chr1:109999838 A/C cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.61 -0.38 2.77e-13 Intelligence (multi-trait analysis); LIHC cis rs1046896 0.594 rs9914570 chr17:80783721 C/T cg22027946 chr17:80790580 TBCD;ZNF750 0.52 7.45 0.37 7.84e-13 Glycated hemoglobin levels; LIHC cis rs1385374 0.858 rs12298615 chr12:129286756 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -5.82 -0.3 1.33e-8 Systemic lupus erythematosus; LIHC cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs10857712 0.950 rs7906765 chr10:135225460 G/T cg01444801 chr10:135216882 MTG1 -0.64 -9.56 -0.46 2.41e-19 Systemic lupus erythematosus; LIHC cis rs12493885 0.769 rs61791508 chr3:153750816 A/G cg10247383 chr3:153839028 SGEF 0.61 5.77 0.3 1.8e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9325144 0.671 rs7486919 chr12:38767997 A/G cg26384229 chr12:38710491 ALG10B -0.56 -7.65 -0.38 2.03e-13 Morning vs. evening chronotype; LIHC cis rs7927592 0.717 rs7126451 chr11:68257386 A/G cg16797656 chr11:68205561 LRP5 -0.52 -9.19 -0.44 3.98e-18 Total body bone mineral density; LIHC cis rs7528419 0.895 rs602633 chr1:109821511 T/G cg06804625 chr1:109812012 CELSR2 -0.4 -5.73 -0.3 2.21e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs1669338 0.588 rs6788122 chr3:3171897 T/C cg16797762 chr3:3221439 CRBN -0.79 -7.15 -0.36 5.26e-12 White matter integrity; LIHC cis rs2455799 0.573 rs2455793 chr3:15743844 A/G cg12698662 chr3:15914712 MIR563 -0.35 -6.36 -0.33 6.42e-10 Mean platelet volume; LIHC trans rs17711722 0.510 rs73142128 chr7:65331109 A/C cg10756647 chr7:56101905 PSPH -0.47 -6.89 -0.35 2.66e-11 Calcium levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03315687 chr19:40932206 SERTAD1 0.38 6.15 0.32 2.13e-9 Cognitive function; LIHC cis rs62458065 1.000 rs1450868 chr7:32463666 G/A cg06627557 chr7:32535165 LSM5;AVL9 -0.65 -7.42 -0.37 9.08e-13 Metabolite levels (HVA/MHPG ratio); LIHC cis rs79976124 0.837 rs12194087 chr6:66644399 T/A cg07460842 chr6:66804631 NA 0.64 6.89 0.35 2.73e-11 Type 2 diabetes; LIHC cis rs8180040 0.800 rs11920354 chr3:47262246 C/A cg27129171 chr3:47204927 SETD2 -0.56 -9.21 -0.45 3.48e-18 Colorectal cancer; LIHC cis rs17106184 0.892 rs11205766 chr1:51191935 T/A cg07174182 chr1:51127561 FAF1 -0.64 -7.32 -0.37 1.77e-12 Type 2 diabetes; LIHC cis rs4853036 0.951 rs6710444 chr2:70120632 G/A cg02498382 chr2:70120550 SNRNP27 -0.41 -6.68 -0.34 9.84e-11 Colorectal or endometrial cancer; LIHC cis rs57920188 0.568 rs12137595 chr1:4094068 C/T cg20703997 chr1:4087676 NA 0.67 6.49 0.33 2.95e-10 Interleukin-17 levels; LIHC cis rs262150 0.731 rs2657388 chr7:158763428 A/G cg19418458 chr7:158789849 NA 0.39 6.36 0.33 6.45e-10 Facial morphology (factor 20); LIHC trans rs911555 0.755 rs8014800 chr14:103946302 T/C cg17675199 chr6:35436792 RPL10A -0.44 -9.12 -0.44 6.8e-18 Intelligence (multi-trait analysis); LIHC trans rs877282 0.898 rs11253341 chr10:765008 G/C cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs7520050 0.966 rs785488 chr1:46576095 G/A cg03146154 chr1:46216737 IPP -0.37 -6.16 -0.32 1.99e-9 Red blood cell count;Reticulocyte count; LIHC cis rs12477438 1.000 rs12466388 chr2:99916538 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -8.5 -0.42 6.15e-16 Chronic sinus infection; LIHC cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg15691649 chr6:25882328 NA -0.63 -8.0 -0.4 1.96e-14 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs2109522 chr4:17658645 T/A cg02297831 chr4:17616191 MED28 0.5 7.83 0.39 6.02e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10744422 1.000 rs3852536 chr12:123333824 C/T cg07706471 chr12:123319906 HIP1R -0.61 -8.02 -0.4 1.68e-14 Schizophrenia; LIHC cis rs6988636 1.000 rs16898088 chr8:124190501 G/A cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs9457247 0.668 rs2236313 chr6:167360389 C/T cg23791538 chr6:167370224 RNASET2 -0.46 -7.31 -0.37 1.93e-12 Crohn's disease; LIHC cis rs2072499 1.000 rs2241107 chr1:156182710 C/T cg25208724 chr1:156163844 SLC25A44 -0.91 -15.94 -0.65 3.5e-43 Testicular germ cell tumor; LIHC cis rs9419702 0.568 rs9419635 chr10:133546164 C/T cg20568497 chr10:133558893 NA 0.4 6.12 0.31 2.59e-9 Survival in rectal cancer; LIHC cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg19318889 chr4:1322082 MAEA 0.47 6.59 0.34 1.68e-10 Obesity-related traits; LIHC cis rs62380364 0.558 rs34319 chr5:88023349 A/T cg22951263 chr5:87985283 NA -0.39 -6.73 -0.34 7.35e-11 Intelligence (multi-trait analysis); LIHC cis rs933688 0.938 rs7705465 chr5:90680949 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.44 0.66 3.67e-45 Smoking behavior; LIHC cis rs8027181 1.000 rs8030477 chr15:73085815 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 7.76 0.39 9.98e-14 Triglyceride levels; LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg07308232 chr7:1071921 C7orf50 -0.42 -6.82 -0.35 4.05e-11 Longevity;Endometriosis; LIHC cis rs4803455 0.565 rs2241713 chr19:41869468 C/G cg08477640 chr19:41863820 B9D2 -0.32 -5.73 -0.3 2.21e-8 Migraine;Coronary artery disease; LIHC trans rs11039798 1.000 rs10769370 chr11:48515430 A/G cg15704280 chr7:45808275 SEPT13 0.62 6.45 0.33 3.86e-10 Axial length; LIHC trans rs61931739 0.534 rs10844840 chr12:34364517 C/T cg26384229 chr12:38710491 ALG10B 0.74 9.18 0.44 4.31e-18 Morning vs. evening chronotype; LIHC cis rs875971 0.825 rs28480509 chr7:66099224 A/G cg11764359 chr7:65958608 NA -0.75 -12.58 -0.56 4.3e-30 Aortic root size; LIHC cis rs4665809 1.000 rs4665819 chr2:26309073 A/G cg27170947 chr2:26402098 FAM59B -0.62 -7.72 -0.39 1.27e-13 Gut microbiome composition (summer); LIHC cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg11987759 chr7:65425863 GUSB 0.39 6.21 0.32 1.56e-9 Aortic root size; LIHC cis rs1005277 0.579 rs2749612 chr10:38488610 G/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.48 -0.46 4.29e-19 Extrinsic epigenetic age acceleration; LIHC cis rs477692 1.000 rs473771 chr10:131408155 A/C cg05714579 chr10:131428358 MGMT 0.46 7.49 0.38 5.86e-13 Response to temozolomide; LIHC cis rs6840360 0.571 rs62327277 chr4:152555905 C/T cg22705602 chr4:152727874 NA -0.32 -6.24 -0.32 1.3e-9 Intelligence (multi-trait analysis); LIHC cis rs7408868 0.908 rs757474 chr19:15273624 T/C cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC cis rs7914558 1.000 rs6584540 chr10:104927634 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.88 -0.43 3.84e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 25.6 0.81 1.67e-81 Prudent dietary pattern; LIHC cis rs1580019 1.000 rs1580019 chr7:32493169 A/T cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -11.29 -0.52 2.41e-25 Cognitive ability; LIHC cis rs8062405 1.000 rs8055982 chr16:28881202 A/C cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2228479 0.702 rs11649501 chr16:89850957 A/T cg19635926 chr16:89946313 TCF25 0.51 6.41 0.33 4.89e-10 Skin colour saturation; LIHC cis rs922107 0.738 rs2390762 chr1:90052626 A/G cg15422784 chr1:90023713 LRRC8B -0.5 -7.99 -0.4 2.06e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs1552244 0.882 rs61429272 chr3:10037320 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs7107174 0.688 rs11237489 chr11:78130325 G/A cg02023728 chr11:77925099 USP35 0.42 7.41 0.37 9.7e-13 Testicular germ cell tumor; LIHC cis rs2084898 0.891 rs501021 chr11:120000872 T/C cg13907859 chr11:120009124 TRIM29 -0.53 -6.57 -0.33 1.86e-10 Stroke (pediatric); LIHC cis rs9612 1.000 rs346524 chr19:44260572 T/C cg08581076 chr19:44259116 C19orf61 0.7 8.95 0.44 2.37e-17 Exhaled nitric oxide output; LIHC trans rs877282 0.891 rs12767043 chr10:797943 C/T cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs10861342 1.000 rs10861350 chr12:105484913 G/A cg23923672 chr12:105501055 KIAA1033 0.64 7.47 0.37 6.71e-13 IgG glycosylation; LIHC cis rs4268898 0.662 rs72795832 chr2:24441855 C/A cg06627628 chr2:24431161 ITSN2 -0.73 -9.82 -0.47 3.16e-20 Asthma; LIHC cis rs9457247 0.967 rs425039 chr6:167410527 C/T cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC cis rs365132 0.870 rs2454949 chr5:176466011 G/A cg16309518 chr5:176445507 NA -0.58 -11.2 -0.52 5.06e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs1577917 0.771 rs2758847 chr6:86349103 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.96 -0.4 2.51e-14 Response to antipsychotic treatment; LIHC cis rs2635047 1.000 rs2635045 chr18:44668417 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.5 6.82 0.35 4.15e-11 Educational attainment; LIHC cis rs34375054 0.573 rs12823172 chr12:125646283 C/G cg25124228 chr12:125621409 AACS -0.43 -6.72 -0.34 7.74e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs7772486 0.875 rs2224121 chr6:146343214 G/A cg13319975 chr6:146136371 FBXO30 -0.34 -5.78 -0.3 1.73e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg12016809 chr21:47604291 C21orf56 0.48 7.17 0.36 4.63e-12 Testicular germ cell tumor; LIHC cis rs7412746 0.611 rs11204748 chr1:150927369 G/T cg17724175 chr1:150552817 MCL1 0.39 7.63 0.38 2.29e-13 Melanoma; LIHC cis rs5753618 0.539 rs5997933 chr22:31672752 A/C cg22777020 chr22:31556080 RNF185 -0.55 -6.29 -0.32 9.49e-10 Colorectal cancer; LIHC cis rs831571 0.550 rs153734 chr3:64078009 A/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.5 -6.61 -0.34 1.44e-10 Type 2 diabetes; LIHC cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg07061783 chr6:25882402 NA -0.78 -9.68 -0.46 9.23e-20 Intelligence (multi-trait analysis); LIHC cis rs208520 0.661 rs1100950 chr6:66827285 A/C cg07460842 chr6:66804631 NA -0.76 -8.35 -0.41 1.75e-15 Exhaled nitric oxide output; LIHC cis rs3213545 0.700 rs2260399 chr12:121469653 C/T cg02403541 chr12:121454288 C12orf43 0.64 12.06 0.55 3.72e-28 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs600806 0.888 rs10858084 chr1:109882250 T/A cg23091122 chr1:110024289 SYPL2 -0.48 -6.46 -0.33 3.67e-10 Intelligence (multi-trait analysis); LIHC cis rs11958404 0.860 rs56090852 chr5:157431120 A/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs1814175 0.817 rs1794164 chr11:49899610 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -23.05 -0.78 1.27e-71 Height; LIHC cis rs898097 0.841 rs55810435 chr17:80836722 G/C cg15664640 chr17:80829946 TBCD -0.76 -12.65 -0.56 2.48e-30 Breast cancer; LIHC cis rs1577917 0.740 rs12212560 chr6:86342679 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.48 -9.28 -0.45 1.99e-18 Response to antipsychotic treatment; LIHC cis rs1865760 0.532 rs9295687 chr6:26082710 T/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08011328 chr6:41889049 MED20;BYSL 0.46 6.63 0.34 1.34e-10 Pancreatic cancer; LIHC cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.58 0.38 3.34e-13 Bipolar disorder; LIHC cis rs7208859 0.673 rs9898858 chr17:29156211 A/T cg14067834 chr17:29058358 SUZ12P 0.69 6.7 0.34 8.36e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7592578 0.771 rs4258824 chr2:191395027 C/T cg27211696 chr2:191398769 TMEM194B -0.58 -7.79 -0.39 8.24e-14 Diastolic blood pressure; LIHC cis rs2637266 1.000 rs11001829 chr10:78343387 A/T cg18941641 chr10:78392320 NA 0.3 6.41 0.33 4.93e-10 Pulmonary function; LIHC cis rs12971120 0.947 rs8084410 chr18:72168486 T/C cg25817165 chr18:72167213 CNDP2 -0.68 -12.6 -0.56 3.74e-30 Refractive error; LIHC cis rs780096 0.545 rs6716894 chr2:27583273 A/G cg21747090 chr2:27597821 SNX17 -0.47 -7.04 -0.36 1.05e-11 Total body bone mineral density; LIHC cis rs4638749 0.734 rs6542756 chr2:108865629 C/G cg06795125 chr2:108905320 SULT1C2 -0.3 -6.06 -0.31 3.57e-9 Blood pressure; LIHC cis rs9916302 0.904 rs1077715 chr17:37683548 A/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.3 -0.58 7.93e-33 Glomerular filtration rate (creatinine); LIHC trans rs1704198 1.000 rs861229 chr1:213898329 C/T cg02442787 chr4:139230014 NA 0.4 6.14 0.32 2.32e-9 Obesity; LIHC cis rs4727027 0.704 rs12535154 chr7:148895304 G/A cg23583168 chr7:148888333 NA -0.79 -11.72 -0.54 6.73e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs34779708 0.833 rs12777517 chr10:35473927 T/G cg04310649 chr10:35416472 CREM -0.42 -5.76 -0.3 1.91e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs8073060 0.586 rs117573546 chr17:33909588 G/A cg19694781 chr19:47549865 TMEM160 1.26 12.96 0.57 1.55e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs35110281 0.659 rs11909064 chr21:45092095 G/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.12 0.31 2.55e-9 Mean corpuscular volume; LIHC cis rs9517313 0.592 rs11069311 chr13:99202101 G/T cg07423050 chr13:99094983 FARP1 -0.5 -8.86 -0.43 4.55e-17 Neuroticism; LIHC cis rs11626933 0.959 rs17799226 chr14:90754538 C/T cg14092571 chr14:90743983 NA -0.9 -14.88 -0.63 5.71e-39 Gut microbiota (bacterial taxa); LIHC cis rs7208859 0.673 rs17826219 chr17:29161845 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1559088 0.803 rs10411529 chr19:33616256 A/C cg17764715 chr19:33622953 WDR88 0.47 7.07 0.36 8.95e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs847649 0.692 rs10257317 chr7:102447056 T/C cg18108683 chr7:102477205 FBXL13 -0.51 -7.83 -0.39 6.02e-14 Morning vs. evening chronotype; LIHC cis rs6762 0.748 rs7929032 chr11:839078 G/A cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.39 -0.45 8.43e-19 Mean platelet volume; LIHC cis rs4746818 0.793 rs2008541 chr10:70860599 A/G cg11621586 chr10:70884670 VPS26A 0.77 10.54 0.5 1.12e-22 Left atrial antero-posterior diameter; LIHC cis rs1568889 1.000 rs2354427 chr11:28049623 T/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.93 0.35 2.04e-11 Bipolar disorder; LIHC cis rs10508774 1.000 rs12413262 chr10:32910504 G/C cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs875971 0.767 rs12668005 chr7:65909021 T/C cg18876405 chr7:65276391 NA 0.35 6.46 0.33 3.65e-10 Aortic root size; LIHC cis rs7312933 0.533 rs11181499 chr12:42818761 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.95 0.39 2.83e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1983891 0.908 rs2148342 chr6:41519522 G/A cg20194872 chr6:41519635 FOXP4 0.4 6.48 0.33 3.16e-10 Prostate cancer; LIHC cis rs9291683 0.551 rs2276961 chr4:10022981 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.48 0.37 6.3e-13 Bone mineral density; LIHC cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC cis rs2153535 0.580 rs9378552 chr6:8463748 G/A cg07606381 chr6:8435919 SLC35B3 0.81 12.31 0.55 4.43e-29 Motion sickness; LIHC cis rs10870270 0.956 rs67378218 chr10:133752420 A/C cg17892150 chr10:133769511 PPP2R2D -0.7 -13.23 -0.58 1.44e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1816752 0.870 rs7320102 chr13:25011573 T/C cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.78e-10 Obesity-related traits; LIHC cis rs11628318 0.614 rs7155883 chr14:103123404 A/C cg12046867 chr14:103022105 NA 0.48 6.88 0.35 2.85e-11 Platelet count; LIHC cis rs10751667 0.666 rs7394992 chr11:980690 G/C cg06064525 chr11:970664 AP2A2 -0.56 -14.53 -0.62 1.34e-37 Alzheimer's disease (late onset); LIHC cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -11.04 -0.51 2e-24 Platelet count; LIHC cis rs10504229 0.679 rs12675340 chr8:58035501 T/A cg20607798 chr8:58055168 NA 0.47 6.75 0.34 6.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs1008375 0.966 rs4698638 chr4:17632988 G/C cg16339924 chr4:17578868 LAP3 0.45 6.3 0.32 9.35e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1707322 1.000 rs11211204 chr1:46317864 A/G cg06784218 chr1:46089804 CCDC17 0.35 6.31 0.32 8.75e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg13409248 chr3:40428643 ENTPD3 0.48 7.86 0.39 4.91e-14 Renal cell carcinoma; LIHC cis rs11971779 0.774 rs6467838 chr7:139043501 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs10751667 0.621 rs10794348 chr11:939941 G/A ch.11.42038R chr11:967971 AP2A2 0.53 9.57 0.46 2.17e-19 Alzheimer's disease (late onset); LIHC cis rs4716602 0.596 rs10949585 chr7:156165258 A/C cg16983916 chr7:156159713 NA -0.33 -5.8 -0.3 1.48e-8 Anti-saccade response; LIHC cis rs10876993 0.890 rs7976852 chr12:58100551 T/G cg18357645 chr12:58087776 OS9 0.51 8.38 0.41 1.38e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs9287719 0.967 rs1541574 chr2:10773508 A/T cg02829992 chr2:10710499 NA -0.38 -6.05 -0.31 3.75e-9 Prostate cancer; LIHC cis rs7086627 0.515 rs7907969 chr10:82153005 T/A cg00277334 chr10:82204260 NA -0.61 -10.07 -0.48 4.66e-21 Post bronchodilator FEV1; LIHC cis rs6912958 0.515 rs381782 chr6:88040649 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.21 0.36 3.64e-12 Monocyte percentage of white cells; LIHC cis rs67981189 0.593 rs8007425 chr14:71508200 A/G cg15816911 chr14:71606274 NA 0.43 6.96 0.35 1.76e-11 Schizophrenia; LIHC cis rs11148252 0.574 rs2038826 chr13:53280013 G/A cg00495681 chr13:53174319 NA 0.68 12.15 0.55 1.69e-28 Lewy body disease; LIHC cis rs16828019 0.852 rs16827876 chr1:41539536 T/G cg20697417 chr1:41786797 NA 0.31 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs9612 1.000 rs346544 chr19:44256205 A/G cg08581076 chr19:44259116 C19orf61 0.68 8.76 0.43 8.95e-17 Exhaled nitric oxide output; LIHC cis rs8177179 1.000 rs8177179 chr3:133463457 G/A cg18769074 chr3:133464867 TF 0.27 6.03 0.31 4.26e-9 Iron status biomarkers (transferrin levels); LIHC cis rs11864453 0.826 rs12448315 chr16:72147242 G/T cg16558253 chr16:72132732 DHX38 -0.5 -8.02 -0.4 1.72e-14 Fibrinogen levels; LIHC cis rs4523957 0.928 rs749240 chr17:2186100 A/G cg16513277 chr17:2031491 SMG6 0.5 7.03 0.36 1.1e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7520050 0.581 rs6671303 chr1:46629653 A/C cg06787764 chr1:46668870 C1orf190;POMGNT1 -0.49 -7.38 -0.37 1.2e-12 Red blood cell count;Reticulocyte count; LIHC cis rs67478160 0.619 rs28698555 chr14:104316486 C/A cg08213375 chr14:104286397 PPP1R13B -0.65 -12.49 -0.56 9.64e-30 Schizophrenia; LIHC cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg16606324 chr3:10149918 C3orf24 0.49 5.71 0.3 2.45e-8 Alzheimer's disease; LIHC cis rs10870270 0.957 rs7074604 chr10:133740373 G/C cg17892150 chr10:133769511 PPP2R2D -0.68 -12.82 -0.57 5.2e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs919433 0.648 rs787975 chr2:198248128 C/T cg10820045 chr2:198174542 NA 0.54 8.65 0.42 2.1e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6840360 1.000 rs1105536 chr4:152605027 C/T cg22705602 chr4:152727874 NA -0.29 -6.06 -0.31 3.6e-9 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.904 rs11867312 chr17:37597748 C/T cg03013999 chr17:37608204 MED1 0.35 5.8 0.3 1.49e-8 Glomerular filtration rate (creatinine); LIHC cis rs5769707 0.616 rs6009786 chr22:50015145 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.61 -0.42 2.68e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs651907 0.557 rs35117343 chr3:101445126 A/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.74 -0.3 2.04e-8 Colorectal cancer; LIHC cis rs2637266 1.000 rs7101318 chr10:78379780 T/C cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC cis rs17685 0.623 rs7782808 chr7:75768645 C/T cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs796364 0.789 rs176008 chr2:200814720 A/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.33 0.41 1.96e-15 Schizophrenia; LIHC cis rs2439831 0.681 rs7176849 chr15:43681427 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.86 15.39 0.64 5.38e-41 Lung cancer in ever smokers; LIHC cis rs2070488 1.000 rs13074160 chr3:38455650 G/T cg24069376 chr3:38537580 EXOG 0.43 7.9 0.39 3.93e-14 Electrocardiographic conduction measures; LIHC cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg24250549 chr1:154909240 PMVK 0.67 10.53 0.49 1.25e-22 Prostate cancer; LIHC cis rs9611565 0.512 rs715498 chr22:42148467 G/A cg03806693 chr22:41940476 POLR3H 0.96 10.03 0.48 6.58e-21 Vitiligo; LIHC cis rs611744 0.967 rs686265 chr8:109199763 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC trans rs17253792 0.822 rs79747476 chr14:56160485 C/A cg26951091 chr14:76844913 ESRRB 0.55 6.09 0.31 2.97e-9 Putamen volume; LIHC cis rs1941023 0.503 rs4939350 chr11:60136243 C/G cg08716584 chr11:60157161 MS4A7 -0.36 -8.18 -0.4 5.66e-15 Congenital heart disease (maternal effect); LIHC cis rs6582630 0.555 rs11181053 chr12:38271364 T/C cg26384229 chr12:38710491 ALG10B -0.38 -5.72 -0.3 2.36e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs2303759 0.626 rs12982246 chr19:49801169 A/G cg22307029 chr19:49891270 CCDC155 0.54 8.39 0.41 1.28e-15 Multiple sclerosis; LIHC cis rs8017423 1.000 rs10129210 chr14:90668379 G/T cg04374321 chr14:90722782 PSMC1 0.7 13.12 0.58 3.83e-32 Mortality in heart failure; LIHC cis rs10791097 0.694 rs1054869 chr11:130742630 G/A cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2412488 0.893 rs17082893 chr4:54353275 C/T cg22241045 chr4:54363911 LNX1 -0.41 -6.72 -0.34 7.68e-11 DNA methylation (variation); LIHC trans rs9914544 0.505 rs7503678 chr17:18776020 A/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.59 -0.34 1.68e-10 Educational attainment (years of education); LIHC trans rs867371 0.964 rs7169961 chr15:82478929 C/T cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.66 -0.34 1.1e-10 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18779695 chr6:36164024 BRPF3 0.41 6.37 0.33 6.24e-10 Cognitive function; LIHC cis rs11628318 0.802 rs2277471 chr14:103024387 A/C cg12046867 chr14:103022105 NA 0.56 8.44 0.42 8.99e-16 Platelet count; LIHC cis rs10791097 0.694 rs4436551 chr11:130755739 A/G cg12179176 chr11:130786555 SNX19 -0.85 -14.08 -0.61 7.52e-36 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6952808 0.729 rs35797753 chr7:1954914 G/A cg21782813 chr7:2030301 MAD1L1 0.48 7.91 0.39 3.58e-14 Bipolar disorder and schizophrenia; LIHC cis rs7613875 0.600 rs2624832 chr3:50030858 C/T cg21467203 chr3:49911342 NA -0.52 -9.67 -0.46 1.07e-19 Body mass index; LIHC trans rs7615952 0.512 rs4234285 chr3:125404477 G/A cg07211511 chr3:129823064 LOC729375 -0.45 -6.14 -0.32 2.31e-9 Blood pressure (smoking interaction); LIHC cis rs7520050 0.872 rs1707308 chr1:46604315 G/A cg23431851 chr1:46668822 C1orf190;POMGNT1 0.38 5.87 0.3 1.04e-8 Red blood cell count;Reticulocyte count; LIHC cis rs8078723 0.714 rs3785550 chr17:38149727 C/T cg17467752 chr17:38218738 THRA -0.59 -10.14 -0.48 2.72e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7833986 0.534 rs72653924 chr8:56906088 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.82 8.33 0.41 1.92e-15 Height; LIHC cis rs9309473 0.583 rs6718864 chr2:73574591 A/G cg20560298 chr2:73613845 ALMS1 -0.44 -7.04 -0.36 1.08e-11 Metabolite levels; LIHC cis rs10861342 1.000 rs10861353 chr12:105515290 T/C cg23923672 chr12:105501055 KIAA1033 0.66 7.75 0.39 1.08e-13 IgG glycosylation; LIHC cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg10295955 chr4:187884368 NA -0.96 -22.55 -0.77 1.2e-69 Lobe attachment (rater-scored or self-reported); LIHC cis rs4423214 1.000 rs1981412 chr11:71138710 T/C cg05163923 chr11:71159392 DHCR7 0.92 14.64 0.62 5.03e-38 Vitamin D levels; LIHC cis rs7131987 0.834 rs1989478 chr12:29442229 C/T cg00204748 chr12:29376779 FAR2 0.34 6.43 0.33 4.3e-10 QT interval; LIHC cis rs79976124 0.800 rs12194767 chr6:66639599 A/G cg07460842 chr6:66804631 NA 0.7 7.74 0.39 1.11e-13 Type 2 diabetes; LIHC cis rs2153535 0.580 rs6597337 chr6:8531652 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.57 0.53 2.35e-26 Motion sickness; LIHC cis rs11718455 0.960 rs13060222 chr3:44005046 A/T cg08738300 chr3:44038990 NA 0.51 8.94 0.44 2.43e-17 Coronary artery disease; LIHC cis rs2354432 0.607 rs7537279 chr1:146673642 A/G cg25205988 chr1:146714368 CHD1L 0.87 5.97 0.31 6.1e-9 Mitochondrial DNA levels; LIHC cis rs9921222 1.000 rs10794639 chr16:377367 A/G cg12437481 chr16:420112 MRPL28 -0.53 -7.47 -0.37 6.91e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs860626 0.536 rs4751627 chr10:119312103 C/T cg10846980 chr10:119306025 EMX2;EMX2OS -0.53 -8.12 -0.4 8.79e-15 Neuroticism; LIHC cis rs6502050 0.799 rs4132775 chr17:80155412 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.73 -0.3 2.16e-8 Life satisfaction; LIHC cis rs7772486 0.875 rs2748483 chr6:146335560 A/T cg13319975 chr6:146136371 FBXO30 0.35 5.86 0.3 1.06e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs748404 0.660 rs2439845 chr15:43722610 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.11e-13 Lung cancer; LIHC cis rs7799006 0.723 rs33922585 chr7:2285178 C/T cg02951883 chr7:2050386 MAD1L1 -0.38 -5.78 -0.3 1.64e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs11673344 0.704 rs571340 chr19:37424883 C/T cg27390819 chr19:37464633 NA -0.51 -6.14 -0.31 2.34e-9 Obesity-related traits; LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg02782426 chr3:40428986 ENTPD3 0.33 6.1 0.31 2.87e-9 Renal cell carcinoma; LIHC cis rs11098499 0.820 rs28535956 chr4:120536858 C/T cg09307838 chr4:120376055 NA -0.73 -11.28 -0.52 2.76e-25 Corneal astigmatism; LIHC cis rs3008870 0.920 rs2755253 chr1:67470843 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.71 11.7 0.53 8.02e-27 Lymphocyte percentage of white cells; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg21468385 chr11:120207433 ARHGEF12 0.43 6.36 0.33 6.43e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10454142 0.700 rs11690845 chr2:48584826 A/G cg15846641 chr2:48541264 FOXN2 -0.46 -5.75 -0.3 1.98e-8 Sex hormone-binding globulin levels; LIHC cis rs6089829 0.855 rs6090203 chr20:61663632 G/A cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs1707322 0.686 rs1250 chr1:46094027 A/G cg24296786 chr1:45957014 TESK2 -0.41 -6.06 -0.31 3.64e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7395662 0.591 rs11039776 chr11:48516706 G/A cg15704280 chr7:45808275 SEPT13 -0.45 -6.72 -0.34 7.45e-11 HDL cholesterol; LIHC cis rs9611519 0.754 rs4820435 chr22:41652846 G/T cg03806693 chr22:41940476 POLR3H -0.72 -8.4 -0.41 1.18e-15 Neuroticism; LIHC cis rs6964587 1.000 rs2188155 chr7:91599825 A/C cg17063962 chr7:91808500 NA 1.01 19.32 0.72 9.73e-57 Breast cancer; LIHC cis rs2251381 0.778 rs722013 chr21:30549245 G/T cg24692254 chr21:30365293 RNF160 0.7 9.84 0.47 2.77e-20 Selective IgA deficiency; LIHC cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.84 0.3 1.23e-8 Calcium levels; LIHC cis rs8180040 0.701 rs12491473 chr3:46989904 G/A cg27129171 chr3:47204927 SETD2 -0.62 -10.65 -0.5 4.76e-23 Colorectal cancer; LIHC trans rs11088226 0.645 rs11702343 chr21:33937888 C/A cg09050820 chr6:167586206 TCP10L2 0.88 13.71 0.6 2.1e-34 Gastritis; LIHC cis rs1707322 1.000 rs10890378 chr1:46410657 A/G cg03146154 chr1:46216737 IPP -0.47 -7.5 -0.38 5.42e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7528419 0.591 rs4970837 chr1:109822008 G/T cg00908766 chr1:109817496 CELSR2 0.43 8.47 0.42 7.24e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs34779708 0.931 rs17583009 chr10:35320915 T/C cg03585969 chr10:35415529 CREM 0.84 12.68 0.57 1.82e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12549902 0.897 rs12549294 chr8:41506380 A/G cg17182837 chr8:41585554 ANK1 -0.23 -5.85 -0.3 1.13e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs2854207 0.505 rs2466957 chr17:61961230 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.75 0.34 6.52e-11 Height; LIHC cis rs7589728 1.000 rs11893832 chr2:88507537 G/C cg04511125 chr2:88470314 THNSL2 0.88 8.49 0.42 6.42e-16 Plasma clusterin levels; LIHC cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg11764359 chr7:65958608 NA 0.58 5.98 0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs12249377 0.519 rs10881838 chr10:92590233 A/G cg14313238 chr10:92632228 RPP30 0.38 6.37 0.33 5.94e-10 White matter microstructure (global fractional anisotropy); LIHC cis rs10861342 1.000 rs10778370 chr12:105603139 T/C cg23923672 chr12:105501055 KIAA1033 0.66 7.7 0.38 1.46e-13 IgG glycosylation; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg26338869 chr17:61819248 STRADA 0.59 8.7 0.43 1.42e-16 Prudent dietary pattern; LIHC cis rs16837677 0.826 rs3795737 chr1:156697056 A/G cg19377421 chr1:156697041 ISG20L2;C1orf66 0.65 7.73 0.39 1.19e-13 Sjögren's syndrome; LIHC trans rs1488564 1.000 rs1488564 chr3:173453868 A/G cg21526220 chr14:64108088 WDR89 -0.43 -6.24 -0.32 1.28e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10870270 1.000 rs10159746 chr10:133742677 C/T cg17892150 chr10:133769511 PPP2R2D -0.69 -12.98 -0.57 1.37e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs28655083 0.956 rs8060627 chr16:77077065 A/G cg01753188 chr16:77233325 SYCE1L;MON1B -0.39 -5.77 -0.3 1.81e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.59 8.45 0.42 8.28e-16 Lymphocyte counts; LIHC cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs34172651 0.583 rs200541 chr16:24733141 A/G cg00339695 chr16:24857497 SLC5A11 -0.68 -9.71 -0.47 7.32e-20 Intelligence (multi-trait analysis); LIHC trans rs1945213 0.694 rs34828123 chr11:55837868 T/A cg03929089 chr4:120376271 NA 0.53 6.8 0.35 4.54e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs2153535 0.580 rs969422 chr6:8451780 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs910316 0.967 rs4899551 chr14:75660246 C/G cg11812906 chr14:75593930 NEK9 -0.7 -13.15 -0.58 2.95e-32 Height; LIHC cis rs17345786 0.861 rs74768235 chr3:101142821 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.55 6.78 0.34 5.38e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs7615952 0.641 rs12488180 chr3:125782236 C/T cg05084668 chr3:125655381 ALG1L -0.41 -6.47 -0.33 3.34e-10 Blood pressure (smoking interaction); LIHC trans rs1805008 0.561 rs8046635 chr16:90123493 C/T cg17139369 chr19:8478169 MARCH2 0.56 6.18 0.32 1.83e-9 Skin colour saturation; LIHC cis rs7100689 0.577 rs2342813 chr10:82046302 T/G cg01528321 chr10:82214614 TSPAN14 0.86 11.98 0.54 7.63e-28 Post bronchodilator FEV1; LIHC cis rs2976388 0.556 rs4736321 chr8:143822194 C/T cg06565975 chr8:143823917 SLURP1 -0.45 -8.35 -0.41 1.76e-15 Urinary tract infection frequency; LIHC cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg05665937 chr4:1216051 CTBP1 0.45 6.29 0.32 9.45e-10 Obesity-related traits; LIHC cis rs1336900 0.513 rs56253522 chr1:150614869 C/A cg15448220 chr1:150897856 SETDB1 0.43 6.59 0.34 1.69e-10 Blood protein levels; LIHC cis rs2280018 0.538 rs7404526 chr16:15129162 A/G cg07549590 chr16:15018862 NA -0.33 -6.19 -0.32 1.71e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10504229 0.593 rs80174614 chr8:58024631 G/A cg02290350 chr8:58132656 NA 0.3 6.85 0.35 3.41e-11 Developmental language disorder (linguistic errors); LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg07157834 chr1:205819609 PM20D1 0.79 12.25 0.55 7.55e-29 Menarche (age at onset); LIHC cis rs1003719 0.667 rs3753073 chr21:38466615 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.57 6.61 0.34 1.5e-10 Eye color traits; LIHC cis rs1144333 0.510 rs1250882 chr1:76287314 C/A cg22875332 chr1:76189707 ACADM -0.43 -6.51 -0.33 2.67e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs6461049 0.765 rs10224497 chr7:2149967 A/G cg20295408 chr7:1910781 MAD1L1 -0.4 -5.87 -0.3 1.02e-8 Schizophrenia; LIHC cis rs7264396 0.676 rs6060723 chr20:34549947 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.56 -0.5 9.76e-23 Total cholesterol levels; LIHC cis rs3791556 0.501 rs3791533 chr2:240100616 G/A cg03281426 chr2:240109471 HDAC4 0.38 6.18 0.32 1.84e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7072216 0.763 rs12763044 chr10:100167451 C/G cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC cis rs9916302 0.904 rs2338798 chr17:37547269 T/C cg07936489 chr17:37558343 FBXL20 0.84 13.73 0.6 1.78e-34 Glomerular filtration rate (creatinine); LIHC cis rs6430585 0.527 rs2289959 chr2:136423904 C/T cg07169764 chr2:136633963 MCM6 0.6 7.32 0.37 1.79e-12 Corneal structure; LIHC trans rs7613875 0.578 rs2526749 chr3:50076734 A/G cg21659725 chr3:3221576 CRBN -0.55 -8.16 -0.4 6.51e-15 Body mass index; LIHC cis rs7647973 0.807 rs4955416 chr3:49108428 T/C cg07636037 chr3:49044803 WDR6 0.76 9.65 0.46 1.18e-19 Menarche (age at onset); LIHC cis rs420259 0.727 rs249871 chr16:23664503 C/T cg05131483 chr16:23706242 ERN2 0.34 5.8 0.3 1.47e-8 Bipolar disorder; LIHC cis rs6785206 0.892 rs6793907 chr3:128391626 A/G cg16766828 chr3:128327626 NA 0.65 7.16 0.36 4.86e-12 Lymphocyte percentage of white cells; LIHC cis rs151997 0.508 rs9292165 chr5:50272619 T/C cg06027927 chr5:50259733 NA 0.54 6.6 0.34 1.61e-10 Callous-unemotional behaviour; LIHC cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.33 0.41 1.99e-15 Platelet count; LIHC cis rs13108904 0.775 rs2279282 chr4:1216033 G/C cg05665937 chr4:1216051 CTBP1 0.53 7.86 0.39 5e-14 Obesity-related traits; LIHC cis rs67311347 1.000 rs34762643 chr3:40475433 C/T cg18306943 chr3:40428807 ENTPD3 0.34 6.06 0.31 3.55e-9 Renal cell carcinoma; LIHC cis rs6456156 0.586 rs7762156 chr6:167485831 A/T cg12798992 chr6:167411361 FGFR1OP 0.44 6.65 0.34 1.13e-10 Primary biliary cholangitis; LIHC trans rs4906332 1.000 rs7155980 chr14:103922419 C/G cg17675199 chr6:35436792 RPL10A 0.34 6.68 0.34 9.71e-11 Coronary artery disease; LIHC trans rs7618501 0.602 rs6780731 chr3:50017478 A/G cg21659725 chr3:3221576 CRBN 0.69 11.19 0.52 5.62e-25 Intelligence (multi-trait analysis); LIHC trans rs2243480 1.000 rs316318 chr7:65612904 A/G cg10756647 chr7:56101905 PSPH 1.1 13.4 0.59 3.42e-33 Diabetic kidney disease; LIHC cis rs9430161 0.579 rs7542354 chr1:11040385 G/A cg02454025 chr1:11042201 C1orf127 0.74 13.42 0.59 2.89e-33 Ewing sarcoma; LIHC cis rs2204008 0.682 rs2320517 chr12:38259239 A/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs2637266 0.967 rs2395407 chr10:78380573 T/A cg18941641 chr10:78392320 NA 0.3 6.53 0.33 2.43e-10 Pulmonary function; LIHC cis rs67981189 0.634 rs221891 chr14:71611627 C/T cg15816911 chr14:71606274 NA -0.42 -6.73 -0.34 7.34e-11 Schizophrenia; LIHC cis rs11190604 0.767 rs11190533 chr10:102190792 T/C cg07080220 chr10:102295463 HIF1AN 0.47 6.93 0.35 2.08e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2153535 0.580 rs4960433 chr6:8523697 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.7 0.43 1.42e-16 Motion sickness; LIHC cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg23758822 chr17:41437982 NA 0.94 17.78 0.69 1.48e-50 Menopause (age at onset); LIHC cis rs4934494 0.768 rs1409357 chr10:91429476 G/A cg19698084 chr10:91461284 KIF20B -0.49 -6.45 -0.33 3.76e-10 Red blood cell count; LIHC cis rs11690935 0.959 rs12692973 chr2:172642057 A/G cg13550731 chr2:172543902 DYNC1I2 0.94 17.92 0.7 3.96e-51 Schizophrenia; LIHC cis rs9818758 0.505 rs11716159 chr3:49631585 G/A cg07636037 chr3:49044803 WDR6 -0.66 -6.17 -0.32 1.95e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg06453172 chr10:134556979 INPP5A -0.62 -7.77 -0.39 9.51e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7927771 0.832 rs11601173 chr11:47401058 A/G cg20135002 chr11:47629003 NA -0.51 -8.59 -0.42 3.11e-16 Subjective well-being; LIHC cis rs727505 1.000 rs10264060 chr7:124486413 C/A cg23710748 chr7:124431027 NA -0.33 -5.93 -0.31 7.54e-9 Lewy body disease; LIHC cis rs950776 0.518 rs2292117 chr15:78834689 C/T cg06917634 chr15:78832804 PSMA4 0.91 13.84 0.6 6.78e-35 Sudden cardiac arrest; LIHC cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg13395646 chr4:1353034 KIAA1530 0.41 6.44 0.33 4.1e-10 Obesity-related traits; LIHC cis rs483180 0.855 rs562038 chr1:120254545 G/C cg19096424 chr1:120255104 PHGDH 0.91 12.07 0.55 3.48e-28 Macular telangiectasia type 2; LIHC cis rs965469 1.000 rs77763497 chr20:3250007 A/G cg25506879 chr20:3388711 C20orf194 -0.58 -6.94 -0.35 1.99e-11 IFN-related cytopenia; LIHC cis rs9814567 0.806 rs9857995 chr3:134316706 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.57 9.25 0.45 2.56e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3768617 0.811 rs6424883 chr1:183037695 T/C ch.1.3577855R chr1:183094577 LAMC1 0.48 7.65 0.38 2.08e-13 Fuchs's corneal dystrophy; LIHC cis rs11971779 0.648 rs10085708 chr7:139110954 A/C cg07862535 chr7:139043722 LUC7L2 0.59 10.17 0.48 2.04e-21 Diisocyanate-induced asthma; LIHC cis rs1023500 0.573 rs13057094 chr22:42470317 T/C cg15557168 chr22:42548783 NA -0.45 -6.98 -0.35 1.52e-11 Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26823989 chr1:87380673 SEP15;HS2ST1 0.42 6.32 0.32 8.22e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg16606324 chr3:10149918 C3orf24 0.53 5.77 0.3 1.73e-8 Alzheimer's disease; LIHC cis rs9309473 0.898 rs6546852 chr2:73833431 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.92 -0.35 2.17e-11 Metabolite levels; LIHC trans rs6906287 0.625 rs9320649 chr6:118693665 A/G cg05944369 chr4:174255616 HMGB2 0.41 6.06 0.31 3.68e-9 Electrocardiographic conduction measures; LIHC cis rs6912958 0.514 rs1980792 chr6:87889917 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.34 -6.4 -0.33 5.01e-10 Monocyte percentage of white cells; LIHC cis rs7927771 0.524 rs7933184 chr11:47682402 C/T cg20307385 chr11:47447363 PSMC3 0.77 11.65 0.53 1.17e-26 Subjective well-being; LIHC cis rs9640161 0.830 rs35635199 chr7:150063342 C/T cg21361702 chr7:150065534 REPIN1 0.54 7.48 0.37 6.36e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs9814567 0.865 rs9834981 chr3:134282279 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -11.92 -0.54 1.22e-27 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9640161 0.789 rs2159234 chr7:150020422 A/T cg10018233 chr7:150070692 REPIN1 0.56 9.41 0.45 7.31e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs7959452 0.590 rs28778648 chr12:69771911 C/A cg14784868 chr12:69753453 YEATS4 0.94 20.34 0.74 7.61e-61 Blood protein levels; LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg02990361 chr1:107599529 PRMT6 -0.61 -9.78 -0.47 4.42e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2404602 0.655 rs4886507 chr15:77209694 T/C cg03037974 chr15:76606532 NA 0.71 13.73 0.6 1.72e-34 Blood metabolite levels; LIHC cis rs4819052 0.679 rs2236450 chr21:46702553 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.51 7.6 0.38 2.81e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11122272 0.735 rs2491416 chr1:231547335 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.67 10.49 0.49 1.65e-22 Hemoglobin concentration; LIHC cis rs7904368 0.806 rs45495501 chr10:16861476 G/A cg23933602 chr10:16859644 RSU1 0.6 5.85 0.3 1.15e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC trans rs7618501 1.000 rs7372725 chr3:49790544 C/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.6 -0.34 1.58e-10 Intelligence (multi-trait analysis); LIHC cis rs2932538 0.961 rs3013441 chr1:113192605 C/T cg22162597 chr1:113214053 CAPZA1 -0.7 -10.52 -0.49 1.3e-22 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs921968 0.643 rs545460 chr2:219392159 A/G cg18887096 chr2:219472410 PLCD4 0.37 6.45 0.33 3.92e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7216064 0.636 rs4638 chr17:66039350 A/G cg12091567 chr17:66097778 LOC651250 0.86 14.74 0.62 2.01e-38 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs1814175 0.669 rs12364577 chr11:49707361 A/C cg03929089 chr4:120376271 NA -0.57 -9.52 -0.46 3.36e-19 Height; LIHC cis rs739401 0.595 rs402806 chr11:3066432 A/G cg05729581 chr11:3078854 CARS -0.46 -6.28 -0.32 1.03e-9 Longevity; LIHC cis rs763121 0.853 rs5757181 chr22:39013522 G/A cg06022373 chr22:39101656 GTPBP1 0.68 11.86 0.54 2.1e-27 Menopause (age at onset); LIHC trans rs903027 0.752 rs11774171 chr8:62477247 C/T cg11014794 chr10:93999688 CPEB3 0.4 6.13 0.31 2.42e-9 Whole-brain volume; LIHC cis rs896854 0.902 rs896852 chr8:95960886 G/T cg09323728 chr8:95962352 TP53INP1 -0.35 -7.8 -0.39 7.55e-14 Type 2 diabetes; LIHC cis rs72627123 0.749 rs10149956 chr14:74649106 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 -0.88 -8.37 -0.41 1.53e-15 Morning vs. evening chronotype; LIHC cis rs11690935 0.959 rs77280952 chr2:172620151 G/C cg13550731 chr2:172543902 DYNC1I2 -0.94 -17.68 -0.69 3.78e-50 Schizophrenia; LIHC cis rs12286929 0.644 rs7942036 chr11:115078356 G/C cg04055981 chr11:115044050 NA 0.54 8.76 0.43 9.05e-17 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6089584 0.893 rs6089306 chr20:60574868 G/A cg06108461 chr20:60628389 TAF4 -0.88 -13.75 -0.6 1.53e-34 Body mass index; LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs7909074 1.000 rs4948925 chr10:45392455 C/T cg04218760 chr10:45406644 TMEM72 -0.23 -7.24 -0.36 2.92e-12 Mean corpuscular volume; LIHC cis rs3862260 0.905 rs3850870 chr1:120161037 C/T cg16322792 chr1:120165303 ZNF697 0.46 8.45 0.42 8.77e-16 Systemic lupus erythematosus; LIHC cis rs4631830 0.869 rs7896437 chr10:51529593 A/C cg20129853 chr10:51489980 NA -0.42 -9.18 -0.44 4.36e-18 Prostate-specific antigen levels; LIHC cis rs35110281 0.659 rs73367822 chr21:45024252 C/T cg21573476 chr21:45109991 RRP1B -0.5 -9.37 -0.45 9.81e-19 Mean corpuscular volume; LIHC cis rs17106184 1.000 rs60788683 chr1:51262653 A/C cg07174182 chr1:51127561 FAF1 -0.64 -7.04 -0.36 1.03e-11 Type 2 diabetes; LIHC cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.74 7.41 0.37 9.67e-13 Platelet count; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17504306 chr11:2951538 PHLDA2 0.43 6.45 0.33 3.75e-10 Calcium levels; LIHC cis rs3106136 0.967 rs12643901 chr4:95145132 C/T cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.18 -0.4 5.45e-15 Capecitabine sensitivity; LIHC cis rs12497850 0.866 rs6791234 chr3:48996137 A/G cg07636037 chr3:49044803 WDR6 0.93 16.31 0.66 1.25e-44 Parkinson's disease; LIHC cis rs858239 0.600 rs7789237 chr7:23124713 T/G cg23682824 chr7:23144976 KLHL7 0.41 6.2 0.32 1.63e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2404602 0.716 rs117129193 chr15:76656803 A/G cg23625390 chr15:77176239 SCAPER 0.37 6.04 0.31 3.98e-9 Blood metabolite levels; LIHC cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg06481639 chr22:41940642 POLR3H 0.6 5.76 0.3 1.89e-8 Vitiligo; LIHC cis rs941873 0.835 rs10762859 chr10:81103370 T/A cg09469691 chr10:81107165 PPIF 0.68 10.52 0.49 1.3e-22 Height; LIHC cis rs9649213 0.593 rs3823740 chr7:97957104 T/G cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.12e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs8067354 0.645 rs2271304 chr17:57814641 A/G cg13753209 chr17:57696993 CLTC 0.76 12.16 0.55 1.65e-28 Hemoglobin concentration; LIHC cis rs921968 0.643 rs1516086 chr2:219431535 C/T cg17980119 chr2:219472607 PLCD4 0.35 5.91 0.3 8.24e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs28374715 0.557 rs11855854 chr15:41434729 G/A cg18705301 chr15:41695430 NDUFAF1 -0.93 -9.44 -0.45 6.15e-19 Ulcerative colitis; LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg07133347 chr1:107600762 PRMT6 -0.4 -5.8 -0.3 1.54e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6088590 0.561 rs6087600 chr20:33157217 T/C cg08999081 chr20:33150536 PIGU 0.69 13.69 0.59 2.57e-34 Coronary artery disease; LIHC cis rs6952808 0.929 rs2280546 chr7:1976863 G/A cg02951883 chr7:2050386 MAD1L1 -0.65 -10.33 -0.49 6.14e-22 Bipolar disorder and schizophrenia; LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg05185784 chr16:90016020 DEF8 -0.45 -5.88 -0.3 9.64e-9 Skin colour saturation; LIHC cis rs6952808 0.595 rs3778982 chr7:2166233 T/C cg20295408 chr7:1910781 MAD1L1 -0.41 -5.98 -0.31 5.74e-9 Bipolar disorder and schizophrenia; LIHC cis rs9918079 0.560 rs7685083 chr4:15610771 G/A cg21123203 chr4:15471301 CC2D2A 0.45 7.24 0.36 3.06e-12 Obesity-related traits; LIHC cis rs6121246 0.567 rs6060261 chr20:30192948 C/G cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs1784581 0.894 rs1790000 chr6:162388707 A/G cg17173639 chr6:162384350 PARK2 0.73 15.59 0.64 8.61e-42 Itch intensity from mosquito bite; LIHC cis rs12986413 0.781 rs2864419 chr19:2183175 A/C cg09261902 chr19:2140048 AP3D1 -0.38 -6.54 -0.33 2.29e-10 Height; LIHC cis rs7027203 0.797 rs4744294 chr9:96612114 C/G cg14598338 chr9:96623480 NA -0.34 -6.68 -0.34 9.71e-11 DNA methylation (variation); LIHC cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg01518246 chr11:63870912 FLRT1;MACROD1 0.47 6.54 0.33 2.27e-10 Mean platelet volume; LIHC cis rs16828019 0.777 rs3738369 chr1:41486408 G/A cg03962019 chr1:41807865 NA 0.49 6.85 0.35 3.43e-11 Intelligence (multi-trait analysis); LIHC cis rs365132 0.875 rs2962844 chr5:176333748 G/T cg16309518 chr5:176445507 NA -0.52 -10.0 -0.48 7.92e-21 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs78456975 1.000 rs4073861 chr2:1563611 G/A cg01028140 chr2:1542097 TPO -0.47 -5.77 -0.3 1.76e-8 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs7666738 0.546 rs10025064 chr4:98914060 A/G cg05340658 chr4:99064831 C4orf37 0.49 6.51 0.33 2.66e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs3793683 0.928 rs2148666 chr10:134553785 A/G cg27297192 chr10:134578999 INPP5A 0.51 8.08 0.4 1.14e-14 Migraine; LIHC cis rs10949834 0.824 rs2285025 chr7:73529976 T/C cg07137043 chr7:73588983 EIF4H -0.6 -6.01 -0.31 4.74e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs2303759 0.507 rs35042238 chr19:49872941 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 6.01 0.31 4.68e-9 Multiple sclerosis; LIHC cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg15691649 chr6:25882328 NA -0.5 -7.44 -0.37 8.05e-13 Blood metabolite levels; LIHC cis rs10845606 0.505 rs2417221 chr12:12829914 C/T cg04607235 chr12:12878440 APOLD1 0.44 6.35 0.32 6.71e-10 Systemic lupus erythematosus; LIHC cis rs67311347 0.577 rs2887951 chr3:40282104 C/G cg00656387 chr3:40428638 ENTPD3 0.38 6.08 0.31 3.29e-9 Renal cell carcinoma; LIHC cis rs9303280 0.806 rs35569035 chr17:38035624 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.15 0.36 5.31e-12 Self-reported allergy; LIHC cis rs34779708 0.966 rs11599606 chr10:35406626 G/A cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2839627 0.598 rs56098337 chr21:44271365 G/T cg18192155 chr21:44258298 NA 0.45 7.11 0.36 6.69e-12 Information processing speed; LIHC cis rs919433 0.679 rs9967823 chr2:198531529 A/G cg10820045 chr2:198174542 NA 0.44 6.79 0.34 5.06e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4917833 1.000 rs4917833 chr10:100217808 A/G cg19043522 chr10:100227446 HPSE2 -0.4 -5.82 -0.3 1.39e-8 Pediatric bone mineral density (femoral neck); LIHC cis rs1707322 0.827 rs10890347 chr1:46242332 A/T cg03146154 chr1:46216737 IPP -0.53 -7.91 -0.39 3.53e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs921968 0.540 rs646295 chr2:219408558 A/C cg02985541 chr2:219472218 PLCD4 0.45 8.6 0.42 2.98e-16 Mean corpuscular hemoglobin concentration; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg17042098 chr1:61519631 NA 0.49 6.59 0.34 1.69e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs2762353 0.505 rs2096386 chr6:25787817 C/T cg03517284 chr6:25882590 NA 0.42 6.33 0.32 7.76e-10 Blood metabolite levels; LIHC cis rs644799 1.000 rs473148 chr11:95628606 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.44 5.92 0.31 7.67e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs57590327 0.504 rs4856349 chr3:81502928 C/T cg07356753 chr3:81810745 GBE1 0.45 6.57 0.33 1.83e-10 Extraversion; LIHC cis rs1712517 0.873 rs1163086 chr10:105039579 A/G cg05636881 chr10:105038444 INA 0.41 6.41 0.33 4.85e-10 Migraine; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg07928289 chr15:42783210 NA -0.44 -6.2 -0.32 1.63e-9 Alopecia areata; LIHC cis rs798554 0.759 rs1636255 chr7:2892804 A/C cg04166393 chr7:2884313 GNA12 -0.54 -8.67 -0.42 1.75e-16 Height; LIHC cis rs2880765 0.566 rs17553249 chr15:86006694 A/G cg10818794 chr15:86012489 AKAP13 -0.42 -6.26 -0.32 1.16e-9 Coronary artery disease; LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg12379764 chr21:47803548 PCNT 0.57 8.57 0.42 3.65e-16 Testicular germ cell tumor; LIHC trans rs11098499 0.913 rs56122576 chr4:120129336 A/G cg25214090 chr10:38739885 LOC399744 0.45 7.32 0.37 1.84e-12 Corneal astigmatism; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01246421 chr22:18632905 USP18 -0.48 -6.14 -0.32 2.24e-9 Systolic blood pressure; LIHC cis rs801193 0.967 rs34356500 chr7:66236607 G/T cg11764359 chr7:65958608 NA 0.71 10.42 0.49 2.8e-22 Aortic root size; LIHC trans rs4332037 0.851 rs10268609 chr7:1962163 A/C cg11693508 chr17:37793320 STARD3 0.71 7.64 0.38 2.21e-13 Bipolar disorder; LIHC cis rs903552 0.800 rs1587107 chr15:102006485 T/C cg06707286 chr15:102010195 PCSK6 -0.49 -6.86 -0.35 3.34e-11 Diabetic kidney disease; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg05185784 chr16:90016020 DEF8 0.44 6.13 0.31 2.44e-9 Skin colour saturation; LIHC cis rs34779708 0.658 rs4934715 chr10:35364992 G/T cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.75e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs769267 0.929 rs2905421 chr19:19457908 G/T cg03709012 chr19:19516395 GATAD2A 0.92 14.68 0.62 3.48e-38 Tonsillectomy; LIHC cis rs897984 0.537 rs8045637 chr16:30818662 C/T cg00531865 chr16:30841666 NA -0.41 -6.72 -0.34 7.74e-11 Dementia with Lewy bodies; LIHC cis rs4728302 0.869 rs10156088 chr7:133592544 G/A cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg14793835 chr3:28283034 CMC1 0.45 6.21 0.32 1.56e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs801193 0.773 rs801207 chr7:66020590 T/C cg26939375 chr7:64535504 NA -0.44 -7.46 -0.37 7.43e-13 Aortic root size; LIHC cis rs17685 0.712 rs10235086 chr7:75833138 G/T cg04610667 chr7:75704037 NA -0.36 -6.41 -0.33 4.96e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs72627123 0.867 rs78496651 chr14:74480070 C/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.2 0.45 3.67e-18 Morning vs. evening chronotype; LIHC cis rs68170813 0.559 rs2395881 chr7:107074323 A/C cg02696742 chr7:106810147 HBP1 -0.5 -5.74 -0.3 2.1e-8 Coronary artery disease; LIHC cis rs1801251 1.000 rs2305137 chr2:233712049 G/A cg08000102 chr2:233561755 GIGYF2 -0.76 -11.63 -0.53 1.47e-26 Coronary artery disease; LIHC cis rs2370759 1.000 rs11594459 chr10:32561858 A/C cg18270830 chr10:32634957 EPC1 0.54 6.59 0.34 1.68e-10 Sexual dysfunction (female); LIHC cis rs6088590 0.965 rs6087639 chr20:33443866 G/A cg24642439 chr20:33292090 TP53INP2 0.74 9.66 0.46 1.11e-19 Coronary artery disease; LIHC cis rs9611519 0.964 rs5995992 chr22:41487218 T/C cg03806693 chr22:41940476 POLR3H -0.71 -7.81 -0.39 6.85e-14 Neuroticism; LIHC cis rs473651 0.935 rs540636 chr2:239358341 T/C cg18131467 chr2:239335373 ASB1 1.08 20.6 0.74 6.86e-62 Multiple system atrophy; LIHC cis rs6840360 0.571 rs1822346 chr4:152525303 G/C cg22705602 chr4:152727874 NA -0.32 -6.24 -0.32 1.31e-9 Intelligence (multi-trait analysis); LIHC cis rs10463316 0.894 rs6891252 chr5:150762807 G/T cg03212797 chr5:150827313 SLC36A1 -0.47 -7.21 -0.36 3.61e-12 Metabolite levels (Pyroglutamine); LIHC trans rs1814175 0.727 rs2140597 chr11:49873946 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.16 0.36 5.01e-12 Height; LIHC cis rs2180341 0.961 rs9375501 chr6:127652539 C/T cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.71 0.34 7.97e-11 Bipolar disorder; LIHC cis rs1059312 1.000 rs3825180 chr12:129279242 A/G cg09035930 chr12:129282057 SLC15A4 -0.65 -12.29 -0.55 5.17e-29 Systemic lupus erythematosus; LIHC cis rs875971 0.540 rs736270 chr7:65428822 T/C cg11987759 chr7:65425863 GUSB -0.38 -6.02 -0.31 4.48e-9 Aortic root size; LIHC trans rs7120489 0.786 rs12281138 chr11:12453702 G/A cg08537300 chr5:179058959 NA 0.56 6.04 0.31 3.95e-9 Mortality in heart failure; LIHC cis rs4920343 0.698 rs851121 chr1:19087765 C/T cg26220594 chr1:19110978 NA 0.28 5.72 0.3 2.38e-8 Knee osteoarthritis; LIHC cis rs4927850 1.000 rs7614767 chr3:195753451 C/T cg12923728 chr3:195709715 SDHAP1 -0.71 -10.09 -0.48 3.85e-21 Pancreatic cancer; LIHC cis rs7937682 0.889 rs490199 chr11:111487890 A/G cg09085632 chr11:111637200 PPP2R1B -0.89 -10.57 -0.5 8.53e-23 Primary sclerosing cholangitis; LIHC cis rs561341 1.000 rs4795667 chr17:30244443 T/C cg12193833 chr17:30244370 NA -0.57 -6.03 -0.31 4.36e-9 Hip circumference adjusted for BMI; LIHC cis rs2153535 0.607 rs9502722 chr6:8541483 C/T cg23788917 chr6:8435910 SLC35B3 0.63 8.73 0.43 1.17e-16 Motion sickness; LIHC cis rs12477438 0.501 rs2632284 chr2:99775865 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.38 0.64 5.93e-41 Chronic sinus infection; LIHC cis rs5769765 0.955 rs8138687 chr22:50291869 A/G cg26441486 chr22:50317300 CRELD2 0.36 6.38 0.33 5.73e-10 Schizophrenia; LIHC cis rs6967414 0.685 rs6944332 chr7:6758018 G/A cg00387323 chr7:6746715 ZNF12 0.67 7.47 0.37 6.56e-13 Hematocrit;Hemoglobin concentration; LIHC cis rs7577696 0.597 rs2280968 chr2:32290040 G/T cg02381751 chr2:32503542 YIPF4 -0.44 -6.07 -0.31 3.4e-9 Inflammatory biomarkers; LIHC cis rs950169 0.580 rs11630887 chr15:85193015 A/T cg03959625 chr15:84868606 LOC388152 0.45 6.32 0.32 8.1e-10 Schizophrenia; LIHC cis rs9443189 0.762 rs2748943 chr6:76435543 C/T cg01950844 chr6:76311363 SENP6 -0.54 -6.92 -0.35 2.17e-11 Prostate cancer; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg13409248 chr3:40428643 ENTPD3 0.49 8.27 0.41 3.08e-15 Renal cell carcinoma; LIHC cis rs1003719 0.788 rs2251161 chr21:38467857 C/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.93 0.54 1.12e-27 Eye color traits; LIHC cis rs6466055 0.720 rs2040914 chr7:104972174 A/G cg04380332 chr7:105027541 SRPK2 0.35 6.74 0.34 6.76e-11 Schizophrenia; LIHC cis rs8058578 1.000 rs8051050 chr16:30687909 A/G cg02466173 chr16:30829666 NA -0.47 -7.37 -0.37 1.29e-12 Multiple myeloma; LIHC trans rs7618501 0.699 rs1317154 chr3:49910084 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.6 9.46 0.46 5.13e-19 Intelligence (multi-trait analysis); LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg02592271 chr2:27665507 KRTCAP3 -0.44 -6.06 -0.31 3.69e-9 Menopause (age at onset); LIHC cis rs6964587 0.585 rs10266481 chr7:91554338 T/C cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.23e-24 Breast cancer; LIHC cis rs7909074 0.966 rs4948645 chr10:45391481 A/G cg04218760 chr10:45406644 TMEM72 -0.24 -7.49 -0.38 6.04e-13 Mean corpuscular volume; LIHC cis rs8062405 0.721 rs151181 chr16:28490517 A/G cg00204512 chr16:28754710 NA 0.35 6.42 0.33 4.63e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2070488 0.965 rs2051216 chr3:38562288 C/T cg24069376 chr3:38537580 EXOG -0.38 -7.04 -0.36 1.06e-11 Electrocardiographic conduction measures; LIHC cis rs240764 0.658 rs6925823 chr6:101179273 C/A cg12253828 chr6:101329408 ASCC3 -0.41 -6.28 -0.32 1.04e-9 Neuroticism; LIHC cis rs2282802 0.711 rs3777095 chr5:139660916 G/A cg26211634 chr5:139558579 C5orf32 0.38 5.85 0.3 1.17e-8 Intelligence (multi-trait analysis); LIHC cis rs6750047 0.585 rs336033 chr2:38263808 A/G cg07380506 chr2:38303506 CYP1B1 -0.59 -7.47 -0.37 6.71e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs9814567 1.000 rs9827987 chr3:134272621 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7208859 0.673 rs73263776 chr17:29211331 G/C cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17376456 0.877 rs13185660 chr5:93336500 G/A cg25358565 chr5:93447407 FAM172A 1.11 10.21 0.48 1.53e-21 Diabetic retinopathy; LIHC cis rs7618501 0.603 rs72942333 chr3:49986118 T/C cg21467203 chr3:49911342 NA -0.44 -7.91 -0.39 3.57e-14 Intelligence (multi-trait analysis); LIHC cis rs2180341 1.000 rs9321073 chr6:127609691 C/T cg27446573 chr6:127587934 RNF146 1.03 15.83 0.65 1e-42 Breast cancer; LIHC cis rs72627509 0.680 rs79641006 chr4:57847443 T/G cg26694713 chr4:57773883 REST 0.65 8.69 0.43 1.53e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs6500602 0.964 rs2304633 chr16:4496973 T/A cg05791018 chr13:19965014 NA -0.28 -6.16 -0.32 2e-9 Schizophrenia; LIHC trans rs3783890 1.000 rs12892710 chr14:93746091 A/C cg02802420 chr16:69363236 PDF;COG8 0.32 6.22 0.32 1.44e-9 Body mass index; LIHC trans rs7618501 0.602 rs9311446 chr3:50092226 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.59 -9.64 -0.46 1.35e-19 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.71 -0.57 1.46e-30 Alzheimer's disease; LIHC cis rs67478160 0.643 rs2295141 chr14:104212949 T/C cg08213375 chr14:104286397 PPP1R13B 0.65 13.0 0.58 1.15e-31 Schizophrenia; LIHC cis rs2243480 1.000 rs4149468 chr7:65825690 T/C cg07424592 chr7:64974309 NA 0.77 8.99 0.44 1.74e-17 Diabetic kidney disease; LIHC cis rs6466055 0.669 rs2003506 chr7:104761741 A/G cg04380332 chr7:105027541 SRPK2 -0.3 -6.04 -0.31 4.02e-9 Schizophrenia; LIHC cis rs477895 0.713 rs11600867 chr11:63972052 T/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 9.75 0.47 5.46e-20 Mean platelet volume; LIHC cis rs875971 0.862 rs10278014 chr7:66051264 C/T cg18252515 chr7:66147081 NA 0.45 6.57 0.33 1.83e-10 Aortic root size; LIHC cis rs2228479 0.850 rs11645916 chr16:89835234 G/A cg04013166 chr16:89971882 TCF25 0.52 6.46 0.33 3.55e-10 Skin colour saturation; LIHC cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg23758822 chr17:41437982 NA 0.94 17.49 0.69 2.15e-49 Menopause (age at onset); LIHC cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs2645694 0.626 rs2703124 chr4:77820626 G/T cg06046430 chr4:77819534 ANKRD56 0.49 6.48 0.33 3.18e-10 Emphysema distribution in smoking; LIHC cis rs7903847 0.642 rs7896100 chr10:99156994 C/T cg06359132 chr10:99160096 RRP12 -0.42 -6.47 -0.33 3.42e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg24209194 chr3:40518798 ZNF619 0.45 6.46 0.33 3.69e-10 Renal cell carcinoma; LIHC cis rs4891159 0.505 rs680253 chr18:74167427 A/C cg24786174 chr18:74118243 ZNF516 -0.77 -15.04 -0.63 1.39e-39 Longevity; LIHC cis rs9325144 0.647 rs11168741 chr12:38989120 C/T cg26384229 chr12:38710491 ALG10B -0.41 -5.82 -0.3 1.36e-8 Morning vs. evening chronotype; LIHC cis rs10791097 0.694 rs2236711 chr11:130739284 G/A cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2235573 0.527 rs139884 chr22:38369976 A/G cg03989125 chr22:38214979 NA -0.44 -6.03 -0.31 4.34e-9 Glioblastoma;Glioma; LIHC cis rs7605378 0.528 rs281767 chr2:200823281 C/A cg17644776 chr2:200775616 C2orf69 0.45 6.62 0.34 1.4e-10 Osteoporosis; LIHC cis rs2274273 0.624 rs10146637 chr14:55744810 G/A cg01864836 chr14:55583639 NA -0.35 -5.8 -0.3 1.48e-8 Protein biomarker; LIHC cis rs736408 0.812 rs9324 chr3:52825585 T/C cg18404041 chr3:52824283 ITIH1 -0.63 -10.32 -0.49 6.61e-22 Bipolar disorder; LIHC cis rs9896933 0.732 rs590886 chr17:80767350 A/G cg20578329 chr17:80767326 TBCD 0.73 7.47 0.37 6.92e-13 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs6089584 0.507 rs6061990 chr20:60628429 T/G cg06108461 chr20:60628389 TAF4 -0.65 -8.84 -0.43 5.19e-17 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17582391 chr3:119814100 GSK3B 0.48 6.61 0.34 1.46e-10 Lung function (FEV1/FVC); LIHC cis rs3008870 1.000 rs12137403 chr1:67437043 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.63 -0.67 6.46e-46 Lymphocyte percentage of white cells; LIHC cis rs870825 0.616 rs2310108 chr4:185639475 C/T cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs8067545 0.750 rs9896411 chr17:19987610 A/T cg13482628 chr17:19912719 NA 0.49 8.22 0.41 4.28e-15 Schizophrenia; LIHC cis rs35306767 0.903 rs11253475 chr10:907262 C/A cg26597838 chr10:835615 NA 1.17 13.75 0.6 1.47e-34 Eosinophil percentage of granulocytes; LIHC cis rs2153535 0.580 rs9405390 chr6:8466209 T/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs10751667 0.643 rs10751671 chr11:944479 T/G cg06064525 chr11:970664 AP2A2 -0.55 -14.97 -0.63 2.48e-39 Alzheimer's disease (late onset); LIHC cis rs3862260 0.509 rs2281493 chr1:120162787 T/C cg11530693 chr1:120165357 ZNF697 0.48 7.54 0.38 4.28e-13 Systemic lupus erythematosus; LIHC cis rs9303401 0.659 rs34275691 chr17:56736640 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg03806693 chr22:41940476 POLR3H 0.99 10.63 0.5 5.22e-23 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2836950 0.545 rs2836959 chr21:40623668 T/G cg11890956 chr21:40555474 PSMG1 -0.43 -6.99 -0.35 1.46e-11 Menarche (age at onset); LIHC cis rs916888 0.773 rs538628 chr17:44787313 G/C cg15921436 chr17:44337874 NA 0.65 6.57 0.33 1.86e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1559088 0.847 rs3786933 chr19:33602881 C/T cg27124370 chr19:33622961 WDR88 0.52 8.19 0.41 5.16e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9303401 0.614 rs34900851 chr17:56566399 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.92 12.58 0.56 4.44e-30 Cognitive test performance; LIHC cis rs6952808 0.929 rs4721217 chr7:1973579 C/T cg21782813 chr7:2030301 MAD1L1 0.46 7.75 0.39 1.05e-13 Bipolar disorder and schizophrenia; LIHC trans rs7193541 0.684 rs8062783 chr16:74691264 C/T cg23598604 chr1:99732472 LPPR4 0.3 6.34 0.32 7.28e-10 Multiple myeloma; LIHC cis rs4718428 0.662 rs34577323 chr7:66310041 G/C cg12165864 chr7:66369176 NA -0.47 -6.82 -0.35 4.17e-11 Corneal structure; LIHC cis rs4517514 0.509 rs10830417 chr11:89871940 A/G cg05041596 chr11:89867385 NAALAD2 0.4 6.4 0.33 5.17e-10 Trans fatty acid levels; LIHC cis rs55665837 0.665 rs11023273 chr11:14630819 G/A cg16394018 chr11:14927549 NA 0.41 5.84 0.3 1.2e-8 Vitamin D levels; LIHC cis rs7659604 0.676 rs6855269 chr4:122697418 T/G cg20573242 chr4:122745356 CCNA2 0.5 7.35 0.37 1.52e-12 Type 2 diabetes; LIHC cis rs8072100 0.512 rs3809863 chr17:45385012 C/T cg08085267 chr17:45401833 C17orf57 -0.58 -8.46 -0.42 7.76e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs17685 0.712 rs11764119 chr7:75812358 T/G cg16684958 chr7:75615977 POR 0.49 8.29 0.41 2.54e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg08888203 chr3:10149979 C3orf24 0.62 6.74 0.34 6.91e-11 Alzheimer's disease; LIHC cis rs3736485 0.966 rs11070852 chr15:51782294 G/T cg08986416 chr15:51914746 DMXL2 -0.39 -5.75 -0.3 1.95e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs861318 0.702 rs3737522 chr1:159021445 A/G cg11003133 chr1:159046391 AIM2 -0.3 -5.77 -0.3 1.74e-8 Obesity-related traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg00760200 chr1:115053833 TRIM33 -0.47 -6.21 -0.32 1.54e-9 Systolic blood pressure; LIHC trans rs11098499 0.722 rs10006192 chr4:120263022 T/C cg25214090 chr10:38739885 LOC399744 0.45 7.32 0.37 1.78e-12 Corneal astigmatism; LIHC cis rs6762477 0.748 rs34877766 chr3:50234126 A/G cg21467203 chr3:49911342 NA -0.34 -5.79 -0.3 1.59e-8 Menarche (age at onset); LIHC cis rs1348850 0.958 rs1548067 chr2:178462914 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.73 11.11 0.52 1.04e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg12016809 chr21:47604291 C21orf56 0.48 7.47 0.37 6.92e-13 Testicular germ cell tumor; LIHC cis rs9682041 0.696 rs11927807 chr3:170096623 A/G cg11886554 chr3:170076028 SKIL 0.63 5.82 0.3 1.35e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs4713118 0.513 rs149941 chr6:28001033 T/C cg23485639 chr6:28045615 ZNF165 0.39 5.94 0.31 7.13e-9 Parkinson's disease; LIHC cis rs6598955 0.724 rs10902731 chr1:26600793 A/G cg04990556 chr1:26633338 UBXN11 -0.63 -10.31 -0.49 6.79e-22 Obesity-related traits; LIHC cis rs12549902 0.800 rs7825337 chr8:41507237 C/T cg17182837 chr8:41585554 ANK1 -0.22 -5.78 -0.3 1.64e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs2180341 0.920 rs4472373 chr6:127705983 G/A cg27446573 chr6:127587934 RNF146 1.03 16.08 0.66 9.97e-44 Breast cancer; LIHC cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 9.9 0.47 1.7e-20 Platelet count; LIHC cis rs6570726 0.764 rs9403733 chr6:145912311 A/C cg13319975 chr6:146136371 FBXO30 -0.43 -6.78 -0.34 5.39e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg18713687 chr3:195489789 MUC4 0.67 10.06 0.48 5.04e-21 Lung disease severity in cystic fibrosis; LIHC cis rs5769765 0.955 rs61136468 chr22:50312679 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.69 -8.98 -0.44 1.9e-17 Schizophrenia; LIHC cis rs12579753 0.879 rs1922552 chr12:82158093 G/T cg07988820 chr12:82153109 PPFIA2 -0.49 -5.94 -0.31 6.82e-9 Resting heart rate; LIHC cis rs797680 0.856 rs602204 chr1:93727579 A/G cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.77 0.3 1.78e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs4925386 1.000 rs4925389 chr20:60922512 G/A cg06026331 chr20:60912101 LAMA5 -0.52 -8.84 -0.43 5.26e-17 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC trans rs877282 1.000 rs71494928 chr10:769134 A/G cg22713356 chr15:30763199 NA 1.38 12.35 0.56 3.16e-29 Uric acid levels; LIHC cis rs9916302 0.904 rs10221223 chr17:37489100 T/G cg00129232 chr17:37814104 STARD3 0.38 6.13 0.31 2.43e-9 Glomerular filtration rate (creatinine); LIHC cis rs801193 1.000 rs2707845 chr7:66198798 C/T cg11764359 chr7:65958608 NA 0.71 10.55 0.5 1.04e-22 Aortic root size; LIHC cis rs1395 0.778 rs11126918 chr2:27438710 G/A cg23587288 chr2:27483067 SLC30A3 -0.31 -5.73 -0.3 2.22e-8 Blood metabolite levels; LIHC cis rs7592578 1.000 rs7592578 chr2:191439591 T/G cg27211696 chr2:191398769 TMEM194B 0.62 7.65 0.38 2e-13 Diastolic blood pressure; LIHC cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg11644478 chr21:40555479 PSMG1 -0.39 -6.09 -0.31 2.96e-9 Cognitive function; LIHC cis rs77637988 0.553 rs10169629 chr2:48625044 G/T cg00032884 chr2:48540671 FOXN2 0.37 5.79 0.3 1.59e-8 Joint mobility (Beighton score); LIHC trans rs1005277 0.505 rs7917943 chr10:38195811 T/A cg23533926 chr12:111358616 MYL2 0.33 6.42 0.33 4.66e-10 Extrinsic epigenetic age acceleration; LIHC trans rs6598955 0.671 rs17163746 chr1:26564230 C/A cg07461501 chr17:79650226 HGS;ARL16 -0.81 -9.1 -0.44 7.57e-18 Obesity-related traits; LIHC cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg17971929 chr21:40555470 PSMG1 -0.39 -5.95 -0.31 6.8e-9 Menarche (age at onset); LIHC cis rs1355223 0.583 rs2941041 chr11:34874734 A/C cg06937548 chr11:34938143 PDHX;APIP 0.42 5.95 0.31 6.68e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs4689388 0.926 rs10012946 chr4:6293350 C/T cg00701064 chr4:6280414 WFS1 -0.47 -7.69 -0.38 1.59e-13 Type 2 diabetes and other traits;Type 2 diabetes; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03359468 chr8:26240463 BNIP3L 0.44 6.15 0.32 2.22e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1371867 0.875 rs1660311 chr8:101330579 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC cis rs7927771 1.000 rs12363232 chr11:47623890 C/T cg18512352 chr11:47633146 NA -0.27 -6.3 -0.32 8.93e-10 Subjective well-being; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00095276 chr5:1068111 SLC12A7 0.52 7.81 0.39 7.14e-14 Cognitive function; LIHC cis rs9633740 1.000 rs7910643 chr10:82251769 G/A cg01528321 chr10:82214614 TSPAN14 0.93 12.07 0.55 3.51e-28 Post bronchodilator FEV1; LIHC cis rs10792665 0.934 rs10792668 chr11:82679581 A/C cg24227371 chr11:82718527 RAB30 -0.31 -7.18 -0.36 4.32e-12 Obesity-related traits; LIHC cis rs12579753 0.871 rs35801863 chr12:82238818 A/T cg07988820 chr12:82153109 PPFIA2 -0.48 -5.82 -0.3 1.39e-8 Resting heart rate; LIHC cis rs13343954 0.825 rs7254716 chr19:33532128 T/C cg27124370 chr19:33622961 WDR88 0.42 5.73 0.3 2.21e-8 Colorectal cancer; LIHC cis rs600806 0.850 rs12073497 chr1:109974450 A/C cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.47 -0.37 6.73e-13 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs9549367 0.713 rs9549352 chr13:113833221 A/G cg00898013 chr13:113819073 PROZ -0.49 -8.11 -0.4 8.91e-15 Platelet distribution width; LIHC cis rs2637266 1.000 rs12252604 chr10:78352591 T/C cg18941641 chr10:78392320 NA 0.29 6.05 0.31 3.81e-9 Pulmonary function; LIHC cis rs4930103 0.534 rs2063550 chr11:1979223 G/C cg23202291 chr11:1979235 NA 0.6 9.47 0.46 4.75e-19 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC trans rs911555 0.723 rs4906324 chr14:103923099 A/G cg17675199 chr6:35436792 RPL10A -0.44 -9.21 -0.45 3.25e-18 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02551910 chr10:12110991 DHTKD1 0.48 6.54 0.33 2.26e-10 Lung function (FEV1/FVC); LIHC cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7561273 0.586 rs11902756 chr2:24300932 A/G cg06627628 chr2:24431161 ITSN2 -0.43 -5.73 -0.3 2.21e-8 Quantitative traits; LIHC cis rs798554 0.757 rs1182171 chr7:2878510 A/G cg04166393 chr7:2884313 GNA12 0.43 5.76 0.3 1.85e-8 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20573562 chr11:18034664 SERGEF 0.49 6.09 0.31 2.98e-9 Lung function (FEV1/FVC); LIHC cis rs17021463 0.902 rs62320439 chr4:95248721 G/C cg11021082 chr4:95130006 SMARCAD1 0.47 8.5 0.42 6.07e-16 Testicular germ cell tumor; LIHC trans rs1814175 0.817 rs7932683 chr11:49983640 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg23131131 chr22:24373011 LOC391322 -0.65 -9.49 -0.46 4.03e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs910316 0.737 rs175055 chr14:75488946 T/G cg11812906 chr14:75593930 NEK9 -0.72 -13.3 -0.58 7.78e-33 Height; LIHC cis rs7927771 0.832 rs7924485 chr11:47419129 A/G cg20135002 chr11:47629003 NA 0.54 9.0 0.44 1.58e-17 Subjective well-being; LIHC cis rs11030122 0.702 rs1349583 chr11:3972236 G/A cg18678763 chr11:4115507 RRM1 -0.57 -8.42 -0.41 1.01e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs10861342 0.892 rs12322134 chr12:105646804 G/C cg23923672 chr12:105501055 KIAA1033 0.67 7.74 0.39 1.12e-13 IgG glycosylation; LIHC cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.88 7.96 0.4 2.59e-14 Platelet count; LIHC cis rs11190604 1.000 rs12358187 chr10:102284449 C/G cg07080220 chr10:102295463 HIF1AN 0.57 8.08 0.4 1.15e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6547741 1.000 rs10165098 chr2:27796526 C/T cg27432699 chr2:27873401 GPN1 0.72 11.61 0.53 1.73e-26 Oral cavity cancer; LIHC cis rs9549367 0.789 rs2287247 chr13:113889212 A/G cg00898013 chr13:113819073 PROZ -0.43 -7.49 -0.38 5.95e-13 Platelet distribution width; LIHC cis rs6750795 0.569 rs1667308 chr2:232406344 T/C cg19187155 chr2:232395269 NMUR1 0.57 9.0 0.44 1.63e-17 Height; LIHC cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg14159672 chr1:205819179 PM20D1 0.72 10.26 0.49 1.02e-21 Menarche (age at onset); LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg17971929 chr21:40555470 PSMG1 0.81 9.67 0.46 1.06e-19 Cognitive function; LIHC cis rs60871478 1.000 rs6460801 chr7:810506 T/C cg27478167 chr7:817139 HEATR2 -0.42 -5.97 -0.31 5.91e-9 Cerebrospinal P-tau181p levels; LIHC cis rs79149102 0.649 rs75985113 chr15:75379312 C/T cg15902774 chr15:75289873 SCAMP5 0.41 5.82 0.3 1.34e-8 Lung cancer; LIHC cis rs12142240 0.698 rs6703669 chr1:46862555 C/T cg00530320 chr1:46809349 NSUN4 0.53 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC cis rs3749237 0.964 rs2352967 chr3:49871641 C/T cg03060546 chr3:49711283 APEH 0.37 5.83 0.3 1.31e-8 Resting heart rate; LIHC cis rs2625529 0.668 rs34189331 chr15:72404573 A/T cg16672083 chr15:72433130 SENP8 -0.3 -5.79 -0.3 1.61e-8 Red blood cell count; LIHC cis rs6998277 1.000 rs34217554 chr8:103646352 T/C cg10187029 chr8:103597600 NA 0.76 8.99 0.44 1.68e-17 Migraine; LIHC trans rs9747201 1.000 rs56283054 chr17:80135326 C/T cg07393940 chr7:158741817 NA -0.57 -6.76 -0.34 5.84e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.61 8.65 0.42 1.97e-16 Lymphocyte counts; LIHC cis rs12594515 1.000 rs57299255 chr15:45996532 C/A cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC trans rs9929218 0.954 rs9925923 chr16:68819614 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.72 -0.43 1.23e-16 Colorectal cancer; LIHC cis rs1215050 0.740 rs1084777 chr4:99017542 C/T cg05340658 chr4:99064831 C4orf37 -0.41 -6.37 -0.33 6.27e-10 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6121246 0.954 rs6060989 chr20:30429763 C/T cg13852791 chr20:30311386 BCL2L1 0.85 9.06 0.44 1e-17 Mean corpuscular hemoglobin; LIHC cis rs55665837 0.961 rs60622588 chr11:14456998 T/C cg19336497 chr11:14380999 RRAS2 -0.44 -8.12 -0.4 8.51e-15 Vitamin D levels; LIHC cis rs4878497 0.646 rs10813816 chr9:32437249 C/T cg14296220 chr9:32431791 ACO1 -0.56 -9.83 -0.47 2.96e-20 Inflammatory skin disease; LIHC cis rs6547741 0.904 rs2384628 chr2:27774702 T/G cg27432699 chr2:27873401 GPN1 0.73 11.31 0.52 2.15e-25 Oral cavity cancer; LIHC cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg03452623 chr4:187889614 NA -0.31 -7.89 -0.39 4.18e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs7618501 0.521 rs868891 chr3:49949071 A/G cg05623727 chr3:50126028 RBM5 0.34 5.86 0.3 1.12e-8 Intelligence (multi-trait analysis); LIHC cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs74544699 1.000 rs353028 chr4:74777223 C/T cg02530824 chr4:74847766 PF4 0.52 6.0 0.31 5.17e-9 Growth-regulated protein alpha levels; LIHC cis rs965469 1.000 rs6051827 chr20:3372007 C/T cg25506879 chr20:3388711 C20orf194 -0.56 -6.7 -0.34 8.49e-11 IFN-related cytopenia; LIHC trans rs2832191 0.626 rs2254796 chr21:30341891 A/G cg14791747 chr16:20752902 THUMPD1 0.46 6.24 0.32 1.26e-9 Dental caries; LIHC cis rs936229 0.798 rs1869959 chr15:75147332 A/C cg14664628 chr15:75095509 CSK -0.85 -14.29 -0.61 1.21e-36 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs4805272 0.539 rs17591634 chr19:29331628 A/C cg04546413 chr19:29218101 NA -0.42 -6.84 -0.35 3.65e-11 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs3806843 1.000 rs6579987 chr5:140183659 T/C cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9640161 0.789 rs3735174 chr7:150020489 T/C cg21361702 chr7:150065534 REPIN1 0.46 6.4 0.33 5.01e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs11105298 0.891 rs6538189 chr12:89885923 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.55 -0.38 3.92e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10751667 0.666 rs4074231 chr11:978219 G/C cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs7927771 0.524 rs11039329 chr11:47684908 A/G cg20307385 chr11:47447363 PSMC3 0.77 11.65 0.53 1.17e-26 Subjective well-being; LIHC cis rs881375 0.678 rs10118357 chr9:123680068 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.45 6.56 0.33 2.01e-10 Rheumatoid arthritis; LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg24693881 chr1:107596107 NA -0.57 -10.04 -0.48 6.09e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7546668 0.652 rs12691551 chr1:15907908 C/G cg11706911 chr1:15910989 AGMAT 0.47 7.46 0.37 7.32e-13 Glomerular filtration rate (creatinine); LIHC cis rs17685 0.743 rs10277259 chr7:75802674 A/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.36 -0.33 6.6e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6722750 0.506 rs12612392 chr2:64373635 G/A cg22352474 chr2:64371530 PELI1 0.57 8.02 0.4 1.72e-14 Neuroticism; LIHC cis rs6596100 0.538 rs10491280 chr5:132196383 G/T cg02081065 chr5:132209139 LEAP2 -0.26 -5.88 -0.3 9.86e-9 Breast cancer; LIHC cis rs1577917 1.000 rs7771342 chr6:86631936 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs10463316 0.894 rs7709994 chr5:150753597 A/T cg03212797 chr5:150827313 SLC36A1 -0.46 -7.07 -0.36 8.73e-12 Metabolite levels (Pyroglutamine); LIHC cis rs13217239 0.646 rs4583981 chr6:26992023 G/T cg18867708 chr6:26865862 GUSBL1 0.53 8.11 0.4 8.86e-15 Schizophrenia; LIHC cis rs7216064 1.000 rs2365764 chr17:65857714 G/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs10493773 0.862 rs12075929 chr1:86248138 A/C cg17807903 chr1:86174739 ZNHIT6 0.47 7.93 0.39 3.13e-14 Urate levels in overweight individuals; LIHC cis rs2730245 0.505 rs1188956 chr7:158690576 G/A cg24397884 chr7:158709396 WDR60 0.41 6.0 0.31 5.06e-9 Height; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.29 -0.32 9.61e-10 Total body bone mineral density; LIHC trans rs1814175 0.754 rs28593359 chr11:50042357 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.71 -0.79 3.38e-74 Height; LIHC cis rs10744422 0.920 rs3896871 chr12:123333610 G/T cg18912006 chr12:123335444 HIP1R -0.63 -7.64 -0.38 2.14e-13 Schizophrenia; LIHC cis rs35110281 0.667 rs4819288 chr21:45120173 C/G cg04455712 chr21:45112962 RRP1B 0.45 7.66 0.38 1.99e-13 Mean corpuscular volume; LIHC cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg23172400 chr8:95962367 TP53INP1 -0.4 -9.22 -0.45 3.12e-18 Type 2 diabetes; LIHC trans rs11098499 0.588 rs2389874 chr4:120554991 A/G cg25214090 chr10:38739885 LOC399744 -0.44 -7.18 -0.36 4.26e-12 Corneal astigmatism; LIHC cis rs4407350 0.748 rs131170 chr22:44901601 C/A cg26276947 chr22:44892394 LDOC1L 0.34 6.61 0.34 1.49e-10 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs10489610 chr1:231517765 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg05290708 chr7:140372864 ADCK2 -0.47 -6.08 -0.31 3.23e-9 Thyroid stimulating hormone; LIHC cis rs9640161 0.750 rs59211922 chr7:150023790 T/G cg10018233 chr7:150070692 REPIN1 0.57 9.63 0.46 1.4e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs7665147 1 rs7665147 chr4:57767327 T/A cg26694713 chr4:57773883 REST 0.74 10.81 0.5 1.3e-23 Platelet count; LIHC cis rs8180040 0.620 rs9844122 chr3:47108330 C/T cg27129171 chr3:47204927 SETD2 0.56 9.35 0.45 1.21e-18 Colorectal cancer; LIHC cis rs9611565 0.546 rs132793 chr22:42063681 A/G cg03806693 chr22:41940476 POLR3H 0.95 9.91 0.47 1.67e-20 Vitiligo; LIHC cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg02290350 chr8:58132656 NA 0.4 8.26 0.41 3.23e-15 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.579 rs2472182 chr10:38388865 T/C cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7903847 0.642 rs7903562 chr10:99154782 T/C cg06359132 chr10:99160096 RRP12 -0.39 -6.22 -0.32 1.47e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2354432 0.825 rs10900347 chr1:146800107 G/C cg25205988 chr1:146714368 CHD1L 1.06 18.4 0.71 4.79e-53 Mitochondrial DNA levels; LIHC cis rs921968 0.541 rs3755042 chr2:219317248 T/C cg02176678 chr2:219576539 TTLL4 -0.57 -8.03 -0.4 1.59e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs4144743 0.528 rs16941802 chr17:45355353 C/G cg18085866 chr17:45331354 ITGB3 0.52 5.72 0.3 2.27e-8 Body mass index; LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg00106254 chr7:1943704 MAD1L1 0.47 7.95 0.39 2.73e-14 Bipolar disorder and schizophrenia; LIHC cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg25364880 chr3:44379878 C3orf23 0.44 6.11 0.31 2.79e-9 Depressive symptoms; LIHC cis rs595982 0.702 rs638050 chr19:49375676 A/G cg21252483 chr19:49399788 TULP2 -0.45 -7.4 -0.37 1.03e-12 Red cell distribution width; LIHC cis rs7635838 0.620 rs1666988 chr3:11284950 A/G cg00170343 chr3:11313890 ATG7 0.57 8.5 0.42 5.96e-16 HDL cholesterol; LIHC cis rs7520050 0.966 rs785494 chr1:46586626 C/A cg03146154 chr1:46216737 IPP -0.37 -6.16 -0.32 1.99e-9 Red blood cell count;Reticulocyte count; LIHC cis rs929354 0.772 rs10228145 chr7:157007337 A/G cg05182265 chr7:156933206 UBE3C -0.33 -6.44 -0.33 4.15e-10 Body mass index; LIHC cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.98 0.54 7.4e-28 Colorectal cancer; LIHC cis rs801193 0.591 rs721717 chr7:66130292 G/T cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs742614 0.533 rs6059499 chr20:32447920 C/T cg06304546 chr20:32448765 NA 0.42 5.93 0.31 7.29e-9 Stearic acid (18:0) levels; LIHC cis rs10911363 0.550 rs10911353 chr1:183489203 G/A cg09173681 chr1:183549694 NCF2 0.53 9.11 0.44 7.07e-18 Systemic lupus erythematosus; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg06391762 chr17:46908391 CALCOCO2 -0.4 -6.24 -0.32 1.33e-9 Alopecia areata; LIHC cis rs4665809 1.000 rs13030858 chr2:26315451 G/A cg27170947 chr2:26402098 FAM59B -0.62 -7.72 -0.39 1.27e-13 Gut microbiome composition (summer); LIHC cis rs11105298 0.891 rs10858881 chr12:89891474 T/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.58 -0.38 3.18e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2242116 0.932 rs1531137 chr3:46943028 T/C cg27129171 chr3:47204927 SETD2 0.48 7.67 0.38 1.79e-13 Birth weight; LIHC cis rs7447593 0.666 rs12659266 chr5:176807197 C/T cg05207973 chr5:176823642 SLC34A1 0.34 5.77 0.3 1.8e-8 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs243505 0.559 rs10215159 chr7:148479071 G/C cg09806900 chr7:148480153 CUL1 0.42 6.29 0.32 9.54e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.13 0.55 2.03e-28 Height; LIHC cis rs546131 0.642 rs61881097 chr11:34821598 C/T cg11058730 chr11:34937778 PDHX;APIP -0.52 -6.2 -0.32 1.6e-9 Lung disease severity in cystic fibrosis; LIHC cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg18305652 chr10:134549665 INPP5A 0.43 6.29 0.32 9.78e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7659604 0.560 rs769238 chr4:122744942 G/A cg19748678 chr4:122722346 EXOSC9 0.66 11.04 0.51 1.88e-24 Type 2 diabetes; LIHC cis rs9467773 1.000 rs1884949 chr6:26568067 G/A cg11502198 chr6:26597334 ABT1 0.46 6.71 0.34 8.01e-11 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg00166722 chr3:10149974 C3orf24 -0.49 -5.73 -0.3 2.19e-8 Alzheimer's disease; LIHC cis rs7917772 0.503 rs11191342 chr10:104344450 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.75 0.57 9.72e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg22800045 chr5:56110881 MAP3K1 0.68 8.61 0.42 2.73e-16 Initial pursuit acceleration; LIHC trans rs916888 0.821 rs415430 chr17:44859144 C/T cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs637571 0.615 rs10160792 chr11:65667149 C/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.41 6.15 0.32 2.11e-9 Eosinophil percentage of white cells; LIHC cis rs7089973 0.604 rs2420065 chr10:116583753 A/G cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs1580019 0.587 rs2392069 chr7:32547154 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.13 25.87 0.81 1.63e-82 Cognitive ability; LIHC cis rs35306767 0.761 rs11253538 chr10:1011166 C/T cg20503657 chr10:835505 NA 0.89 8.44 0.42 9.23e-16 Eosinophil percentage of granulocytes; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg26861219 chr6:157472057 ARID1B 0.36 6.09 0.31 3.05e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs6598955 0.671 rs11247880 chr1:26568926 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.8 -8.88 -0.43 3.88e-17 Obesity-related traits; LIHC cis rs72627123 0.867 rs11848920 chr14:74476866 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.95 0.31 6.57e-9 Morning vs. evening chronotype; LIHC cis rs16854884 0.690 rs35885310 chr3:143771333 A/G cg06585982 chr3:143692056 C3orf58 0.54 6.75 0.34 6.45e-11 Economic and political preferences (feminism/equality); LIHC cis rs4642101 0.640 rs9877049 chr3:12821231 A/G cg24848339 chr3:12840334 CAND2 0.31 6.49 0.33 2.95e-10 QRS complex (12-leadsum); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg16982658 chr22:20104937 RANBP1;TRMT2A 0.4 6.05 0.31 3.76e-9 Hepatitis; LIHC cis rs2073300 0.609 rs6137931 chr20:23376875 G/C cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9858542 0.953 rs11719996 chr3:49525958 T/C cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6840360 0.533 rs1397683 chr4:152715916 T/C cg22705602 chr4:152727874 NA 0.39 8.11 0.4 9.38e-15 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.541 rs838824 chr9:111670707 T/C cg05043794 chr9:111880884 C9orf5 0.28 7.01 0.35 1.3e-11 Menarche (age at onset); LIHC cis rs782590 0.774 rs782632 chr2:55898290 C/G cg03859395 chr2:55845619 SMEK2 0.79 13.39 0.59 3.71e-33 Metabolic syndrome; LIHC cis rs2032447 0.507 rs478349 chr6:25894057 T/C cg03264133 chr6:25882463 NA -1.09 -14.09 -0.61 7.1e-36 Intelligence (multi-trait analysis); LIHC cis rs79839061 0.518 rs3755960 chr4:895060 G/T cg07828340 chr4:882639 GAK 0.78 6.47 0.33 3.38e-10 Intelligence (multi-trait analysis); LIHC cis rs921943 0.554 rs163132 chr5:78285921 A/G cg26802063 chr5:78281964 ARSB 0.5 7.55 0.38 3.89e-13 Blood and toenail selenium levels;Blood trace element (Se levels); LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg05064044 chr6:292385 DUSP22 -0.53 -7.11 -0.36 7.01e-12 Menopause (age at onset); LIHC cis rs6024905 0.551 rs2425364 chr20:36969340 G/T cg07053727 chr20:36965646 BPI 0.57 10.64 0.5 4.92e-23 Bipolar disorder and schizophrenia; LIHC cis rs2412488 0.925 rs6852884 chr4:54236559 G/A cg22241045 chr4:54363911 LNX1 -0.44 -6.84 -0.35 3.71e-11 DNA methylation (variation); LIHC cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg21724239 chr8:58056113 NA 0.6 7.39 0.37 1.1e-12 Developmental language disorder (linguistic errors); LIHC cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg23172400 chr8:95962367 TP53INP1 -0.36 -8.12 -0.4 8.43e-15 Type 2 diabetes; LIHC cis rs7264396 0.563 rs6060580 chr20:34310512 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.76 -0.43 9.08e-17 Total cholesterol levels; LIHC cis rs8064299 0.967 rs7420 chr17:72765215 A/G cg25054828 chr17:72772726 NAT9;TMEM104 -0.66 -11.16 -0.52 7.45e-25 Monocyte count; LIHC cis rs2073499 0.810 rs78501918 chr3:50369914 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.79 8.16 0.4 6.68e-15 Schizophrenia; LIHC cis rs9921222 0.565 rs10903014 chr16:377623 A/G cg00101154 chr16:420108 MRPL28 -0.43 -6.82 -0.35 4.05e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs7769051 1.000 rs9493438 chr6:133098349 T/C cg22852734 chr6:133119734 C6orf192 0.94 9.16 0.44 4.77e-18 Type 2 diabetes nephropathy; LIHC cis rs7116495 1.000 rs2511116 chr11:71802160 G/A cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs9309711 0.961 rs35067331 chr2:3474085 C/T cg10845886 chr2:3471009 TTC15 -0.61 -11.32 -0.52 1.89e-25 Neurofibrillary tangles; LIHC cis rs6793245 0.960 rs7373779 chr3:38593943 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.46 -6.76 -0.34 5.88e-11 QT interval; LIHC cis rs6960043 0.818 rs10228066 chr7:15063569 C/T cg19272540 chr7:15055459 NA -0.24 -6.53 -0.33 2.38e-10 Type 2 diabetes; LIHC cis rs4555082 0.834 rs28846738 chr14:105745781 A/G cg13114125 chr14:105738426 BRF1 -0.73 -9.71 -0.46 7.44e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs56775891 1.000 rs56775891 chr18:77575613 C/T cg13263691 chr18:77568018 NA 0.24 6.33 0.32 7.82e-10 Schizophrenia; LIHC cis rs2806561 0.514 rs7519093 chr1:23541078 A/T cg19743168 chr1:23544995 NA -0.41 -6.25 -0.32 1.2e-9 Height; LIHC cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg03396347 chr1:1875803 NA -0.47 -8.72 -0.43 1.24e-16 Body mass index; LIHC cis rs4700695 0.719 rs27086 chr5:65453185 A/G cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.46e-15 Facial morphology (factor 19); LIHC cis rs7071206 0.947 rs4979902 chr10:79399946 C/T cg07817648 chr10:79422355 NA 0.36 7.44 0.37 8.17e-13 Bone mineral density; LIHC cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg11062466 chr8:58055876 NA 0.39 5.73 0.3 2.23e-8 Developmental language disorder (linguistic errors); LIHC cis rs847649 0.692 rs6949391 chr7:102446863 C/T cg18108683 chr7:102477205 FBXL13 -0.51 -7.83 -0.39 6.02e-14 Morning vs. evening chronotype; LIHC cis rs734999 0.566 rs10752747 chr1:2524915 G/T cg18854424 chr1:2615690 NA 0.33 7.27 0.37 2.48e-12 Ulcerative colitis; LIHC cis rs7666738 0.716 rs9994641 chr4:99101605 C/T cg05340658 chr4:99064831 C4orf37 0.68 12.11 0.55 2.47e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs1801251 1.000 rs2674839 chr2:233669040 G/C cg25237894 chr2:233734115 C2orf82 0.59 11.46 0.53 6.04e-26 Coronary artery disease; LIHC cis rs597539 0.652 rs559032 chr11:68710847 G/T cg06028808 chr11:68637592 NA 0.45 5.82 0.3 1.35e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs3096299 0.802 rs3102336 chr16:89442006 C/T cg06640241 chr16:89574553 SPG7 0.58 9.03 0.44 1.24e-17 Multiple myeloma (IgH translocation); LIHC cis rs116095464 0.558 rs9312979 chr5:222057 A/C cg22857025 chr5:266934 NA -1.63 -16.72 -0.67 2.82e-46 Breast cancer; LIHC cis rs75064307 0.834 rs4588370 chr3:108114050 G/A cg03329597 chr3:108125523 MYH15 0.51 6.88 0.35 2.94e-11 Intelligence (multi-trait analysis); LIHC cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg08048268 chr3:133502702 NA -0.41 -6.17 -0.32 1.91e-9 Iron status biomarkers; LIHC cis rs5769707 0.632 rs6009782 chr22:50010812 C/G cg01652190 chr22:50026171 C22orf34 -0.34 -7.61 -0.38 2.7e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7772486 0.790 rs4435956 chr6:146232403 G/C cg13319975 chr6:146136371 FBXO30 0.35 5.81 0.3 1.44e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7617773 0.851 rs6775179 chr3:48313418 T/C cg11946769 chr3:48343235 NME6 0.87 11.2 0.52 5.12e-25 Coronary artery disease; LIHC cis rs2274273 0.870 rs10134339 chr14:55814380 T/C cg01864836 chr14:55583639 NA -0.4 -7.52 -0.38 4.98e-13 Protein biomarker; LIHC trans rs61931739 0.517 rs7486246 chr12:34526419 T/G cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs7552404 1.000 rs9662166 chr1:76235906 C/A cg03433033 chr1:76189801 ACADM 0.68 9.31 0.45 1.57e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6066825 0.555 rs6019378 chr20:47309716 C/T cg18078177 chr20:47281410 PREX1 0.41 6.88 0.35 2.84e-11 Colorectal cancer; LIHC cis rs8180040 1.000 rs807931 chr3:47389317 C/T cg27129171 chr3:47204927 SETD2 0.66 11.38 0.52 1.19e-25 Colorectal cancer; LIHC cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg11890956 chr21:40555474 PSMG1 1.06 15.48 0.64 2.51e-41 Cognitive function; LIHC cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg23758822 chr17:41437982 NA 0.94 17.94 0.7 3.44e-51 Menopause (age at onset); LIHC cis rs7523273 0.565 rs2985104 chr1:207892012 C/T cg22525895 chr1:207977042 MIR29B2 -0.53 -7.94 -0.39 3e-14 Schizophrenia; LIHC cis rs5769707 0.967 rs763127 chr22:50006078 C/T cg01652190 chr22:50026171 C22orf34 -0.29 -6.85 -0.35 3.44e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs66573146 0.831 rs56081162 chr4:6989718 C/T cg00086871 chr4:6988644 TBC1D14 0.88 6.01 0.31 4.81e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2836950 0.501 rs2056844 chr21:40670460 G/C cg06238570 chr21:40685208 BRWD1 -0.47 -7.59 -0.38 2.99e-13 Menarche (age at onset); LIHC cis rs7582180 0.629 rs13025184 chr2:100944842 A/G cg14675211 chr2:100938903 LONRF2 0.52 8.21 0.41 4.57e-15 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg03517284 chr6:25882590 NA -1.08 -16.93 -0.68 3.93e-47 Urate levels; LIHC cis rs1577917 0.958 rs13207354 chr6:86700263 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.38 -0.33 5.85e-10 Response to antipsychotic treatment; LIHC cis rs12479064 0.724 rs737094 chr2:100089078 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.64 -6.75 -0.34 6.37e-11 Chronic sinus infection; LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg00656387 chr3:40428638 ENTPD3 0.49 8.28 0.41 2.86e-15 Renal cell carcinoma; LIHC cis rs7613875 0.580 rs6808044 chr3:50136165 A/G cg21467203 chr3:49911342 NA 0.51 9.19 0.44 3.98e-18 Body mass index; LIHC cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg22963979 chr7:1858916 MAD1L1 -0.38 -6.15 -0.32 2.19e-9 Bipolar disorder and schizophrenia; LIHC cis rs5769707 0.681 rs135879 chr22:50018651 C/T cg07959070 chr22:50026188 C22orf34 -0.34 -8.68 -0.42 1.61e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg07677032 chr17:61819896 STRADA 0.43 6.13 0.31 2.48e-9 Prudent dietary pattern; LIHC cis rs67311347 0.955 rs6764102 chr3:40378153 C/G cg24209194 chr3:40518798 ZNF619 0.46 6.56 0.33 1.95e-10 Renal cell carcinoma; LIHC cis rs9326248 0.954 rs10790177 chr11:117048417 A/G cg11861562 chr11:117069780 TAGLN 0.48 8.03 0.4 1.56e-14 Blood protein levels; LIHC cis rs8062405 0.964 rs11864107 chr16:28885931 T/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg19635926 chr16:89946313 TCF25 0.52 7.0 0.35 1.35e-11 Skin colour saturation; LIHC trans rs60843830 1.000 rs62114501 chr2:231741 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.5 0.46 3.84e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC trans rs61931739 0.500 rs1601628 chr12:34047375 A/C cg26384229 chr12:38710491 ALG10B 0.47 6.62 0.34 1.36e-10 Morning vs. evening chronotype; LIHC cis rs9910055 0.530 rs2269908 chr17:42294198 G/C cg13607699 chr17:42295918 UBTF 0.66 11.68 0.53 9.17e-27 Total body bone mineral density; LIHC cis rs875971 0.862 rs6962717 chr7:65883735 G/A cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs1144333 0.655 rs79322031 chr1:76391978 C/T cg03433033 chr1:76189801 ACADM 0.54 7.58 0.38 3.31e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs11229555 0.574 rs11229454 chr11:58203682 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs600806 0.778 rs891379 chr1:110003605 A/G cg16275483 chr1:110013120 SYPL2 -0.52 -6.3 -0.32 9.12e-10 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.903 rs2194518 chr12:29419460 C/T cg14222432 chr12:29376421 FAR2 0.35 6.53 0.33 2.4e-10 QT interval; LIHC cis rs2576037 0.583 rs8098948 chr18:44512332 C/A cg19077165 chr18:44547161 KATNAL2 -0.47 -7.13 -0.36 5.84e-12 Personality dimensions; LIHC cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.05e-17 Bipolar disorder; LIHC cis rs79976124 0.842 rs1548154 chr6:66624910 G/A cg07460842 chr6:66804631 NA 0.65 7.02 0.35 1.21e-11 Type 2 diabetes; LIHC cis rs11758351 1.000 rs111596617 chr6:26191678 A/T cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC trans rs1945213 0.694 rs7106894 chr11:55877315 T/C cg03929089 chr4:120376271 NA 0.55 7.16 0.36 4.85e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs875971 0.545 rs6460281 chr7:65681115 A/C cg11764359 chr7:65958608 NA 0.5 6.94 0.35 1.99e-11 Aortic root size; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg06123940 chr18:29597493 RNF125 0.43 6.13 0.31 2.44e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs112158604 1 rs112158604 chr1:150696792 TCTTCTGCAG/T cg18016565 chr1:150552671 MCL1 -0.5 -10.14 -0.48 2.62e-21 Lymphocyte counts; LIHC cis rs2839186 0.771 rs13049175 chr21:47641326 G/A cg11766577 chr21:47581405 C21orf56 0.45 7.45 0.37 7.66e-13 Testicular germ cell tumor; LIHC cis rs7107174 1.000 rs1017908 chr11:77948095 A/G cg02023728 chr11:77925099 USP35 0.52 9.85 0.47 2.68e-20 Testicular germ cell tumor; LIHC cis rs1559088 0.947 rs7256182 chr19:33558591 G/A cg17764715 chr19:33622953 WDR88 0.41 5.79 0.3 1.61e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.67e-12 Bipolar disorder; LIHC cis rs6089584 1.000 rs6089584 chr20:60564086 G/C cg06108461 chr20:60628389 TAF4 -0.9 -13.9 -0.6 3.85e-35 Body mass index; LIHC cis rs17818399 0.620 rs1598517 chr2:46857401 C/T cg02822958 chr2:46747628 ATP6V1E2 0.37 5.87 0.3 1.01e-8 Height; LIHC cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg10862848 chr6:42927986 GNMT -0.3 -6.8 -0.35 4.71e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs1348850 0.872 rs4893824 chr2:178298104 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.91 14.41 0.61 3.92e-37 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10637722 1 rs10637722 chr13:61742144 A/ACT cg09384787 chr13:61988802 PCDH20 -0.33 -5.89 -0.3 9.37e-9 beta-nerve growth factor levels; LIHC cis rs7772486 0.875 rs2777476 chr6:146345024 A/G cg13319975 chr6:146136371 FBXO30 -0.37 -6.12 -0.31 2.58e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7914558 1.000 rs7914558 chr10:104775908 G/A cg04362960 chr10:104952993 NT5C2 0.38 5.75 0.3 1.98e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs8002861 0.781 rs3816311 chr13:44453783 G/A cg17145862 chr1:211918768 LPGAT1 0.61 11.76 0.54 4.78e-27 Leprosy; LIHC cis rs3806843 0.741 rs2563293 chr5:140110536 T/C cg16179182 chr5:140090404 VTRNA1-1 0.36 5.84 0.3 1.22e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs752092 0.855 rs7171515 chr15:101769618 C/T cg25114630 chr15:101792522 CHSY1 0.58 7.21 0.36 3.63e-12 Corneal structure; LIHC cis rs7412746 0.658 rs7526489 chr1:150726238 C/T cg17724175 chr1:150552817 MCL1 0.48 9.55 0.46 2.57e-19 Melanoma; LIHC trans rs6952808 0.792 rs2056478 chr7:1953897 C/T cg04565464 chr8:145669602 NFKBIL2 0.4 6.19 0.32 1.71e-9 Bipolar disorder and schizophrenia; LIHC cis rs2370759 1.000 rs16933225 chr10:32599464 C/T cg05361325 chr10:32636312 EPC1 -0.49 -6.0 -0.31 4.96e-9 Sexual dysfunction (female); LIHC cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg05590025 chr7:65112418 INTS4L2 -0.45 -6.97 -0.35 1.67e-11 Calcium levels; LIHC cis rs7772486 0.875 rs6934467 chr6:146410529 G/T cg23711669 chr6:146136114 FBXO30 0.64 10.8 0.5 1.37e-23 Lobe attachment (rater-scored or self-reported); LIHC trans rs8002861 0.810 rs9533664 chr13:44440527 T/C cg17145862 chr1:211918768 LPGAT1 0.58 10.82 0.5 1.17e-23 Leprosy; LIHC cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.84 0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg07424592 chr7:64974309 NA 0.8 8.97 0.44 1.98e-17 Diabetic kidney disease; LIHC trans rs941408 0.963 rs2537855 chr19:2806574 A/G cg19676328 chr12:49525230 TUBA1B -0.38 -6.25 -0.32 1.25e-9 Total cholesterol levels; LIHC cis rs5769765 0.825 rs7511620 chr22:50307932 T/C cg02269571 chr22:50332266 NA -0.77 -10.19 -0.48 1.76e-21 Schizophrenia; LIHC cis rs933688 0.583 rs10036206 chr5:90609178 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.4 6.19 0.32 1.68e-9 Smoking behavior; LIHC trans rs7618501 0.633 rs9853222 chr3:50022926 T/C cg21659725 chr3:3221576 CRBN 0.71 11.58 0.53 2.16e-26 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.500 rs11053282 chr12:34561151 T/C cg26384229 chr12:38710491 ALG10B 0.81 9.89 0.47 1.82e-20 Morning vs. evening chronotype; LIHC cis rs12701220 0.689 rs12530960 chr7:1095471 G/A cg02733842 chr7:1102375 C7orf50 -0.69 -7.49 -0.38 5.79e-13 Bronchopulmonary dysplasia; LIHC cis rs1008375 0.902 rs12503164 chr4:17656107 C/T cg04450456 chr4:17643702 FAM184B 0.34 5.72 0.3 2.31e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs479844 1.000 rs479844 chr11:65551957 A/G cg17712092 chr4:129076599 LARP1B -0.48 -6.78 -0.34 5.36e-11 Allergic disease (asthma, hay fever or eczema);Atopic march;Atopic dermatitis; LIHC cis rs6461049 0.638 rs1859993 chr7:2183702 A/G cg21782813 chr7:2030301 MAD1L1 0.34 5.96 0.31 6.16e-9 Schizophrenia; LIHC cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4555082 0.874 rs4677 chr14:105717279 T/C cg10792982 chr14:105748885 BRF1 0.46 6.33 0.32 7.88e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs651907 0.557 rs11720745 chr3:101441690 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.45 -0.33 3.81e-10 Colorectal cancer; LIHC cis rs11764590 0.950 rs11514731 chr7:2051503 C/G cg23422044 chr7:1970798 MAD1L1 -0.53 -6.15 -0.32 2.22e-9 Neuroticism; LIHC cis rs2412488 0.927 rs4864760 chr4:54283313 A/G cg22241045 chr4:54363911 LNX1 0.4 6.6 0.34 1.57e-10 DNA methylation (variation); LIHC cis rs7666738 0.546 rs10010088 chr4:98655945 C/T cg05340658 chr4:99064831 C4orf37 0.49 6.26 0.32 1.16e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs11792861 0.926 rs10512391 chr9:111809530 A/G cg05043794 chr9:111880884 C9orf5 -0.25 -5.78 -0.3 1.67e-8 Menarche (age at onset); LIHC cis rs67311347 0.869 rs7646899 chr3:40366982 A/G cg18306943 chr3:40428807 ENTPD3 0.36 6.1 0.31 2.84e-9 Renal cell carcinoma; LIHC cis rs1707322 0.721 rs10890346 chr1:46223892 C/T cg06784218 chr1:46089804 CCDC17 -0.4 -7.41 -0.37 1.02e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1799949 1.000 rs4793229 chr17:41418334 C/T cg23758822 chr17:41437982 NA -0.93 -17.25 -0.68 2.02e-48 Menopause (age at onset); LIHC cis rs6912958 0.781 rs7757636 chr6:88256092 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.87 -0.39 4.86e-14 Monocyte percentage of white cells; LIHC trans rs72960926 0.744 rs55792900 chr6:74924010 C/A cg07247405 chr1:2484626 LOC115110 0.55 6.58 0.34 1.75e-10 Metabolite levels (MHPG); LIHC cis rs67981189 0.593 rs221906 chr14:71597393 C/G cg15816911 chr14:71606274 NA 0.39 6.28 0.32 1.02e-9 Schizophrenia; LIHC cis rs11792861 0.926 rs17729523 chr9:111773317 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.69 0.43 1.58e-16 Menarche (age at onset); LIHC cis rs67311347 1.000 rs6762997 chr3:40478151 C/T cg13409248 chr3:40428643 ENTPD3 0.42 7.14 0.36 5.71e-12 Renal cell carcinoma; LIHC cis rs10792665 0.611 rs2170010 chr11:82640826 C/T cg24227371 chr11:82718527 RAB30 0.27 6.05 0.31 3.86e-9 Obesity-related traits; LIHC cis rs921968 0.541 rs526897 chr2:219433597 C/T cg02985541 chr2:219472218 PLCD4 0.44 7.32 0.37 1.74e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs2455799 0.613 rs4685269 chr3:15942354 A/G cg12698662 chr3:15914712 MIR563 -0.34 -6.41 -0.33 4.94e-10 Mean platelet volume; LIHC trans rs1945213 0.694 rs12422168 chr11:55866840 A/G cg15704280 chr7:45808275 SEPT13 0.62 8.11 0.4 8.95e-15 Acute lymphoblastic leukemia (childhood); LIHC cis rs694739 0.734 rs663743 chr11:64107735 G/A cg23796481 chr11:64053134 BAD;GPR137 0.58 8.04 0.4 1.49e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs4243830 0.850 rs2274553 chr1:6586553 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 -0.79 -9.81 -0.47 3.4e-20 Body mass index; LIHC cis rs11588062 0.601 rs4660344 chr1:46805222 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.47 7.42 0.37 9.49e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2243480 1.000 rs34192067 chr7:65887657 C/A cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.79 -13.46 -0.59 1.92e-33 Age at first birth; LIHC trans rs1814175 0.645 rs1818895 chr11:50031523 G/T cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC trans rs11165623 0.564 rs7525803 chr1:97000791 T/C cg10631902 chr5:14652156 NA -0.29 -6.81 -0.35 4.31e-11 Hip circumference;Waist circumference; LIHC cis rs600806 0.778 rs2115787 chr1:110003840 T/G cg23091122 chr1:110024289 SYPL2 -0.48 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs72843506 1.000 rs10459969 chr17:19935901 T/C cg12065943 chr17:19881925 AKAP10 -0.35 -6.33 -0.32 7.88e-10 Schizophrenia; LIHC cis rs61990749 0.597 rs1006039 chr14:78263196 C/T cg21497246 chr14:78225524 SNW1;C14orf178 0.52 7.35 0.37 1.5e-12 Fibroblast growth factor basic levels; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg27432699 chr2:27873401 GPN1 -0.51 -7.35 -0.37 1.5e-12 Total body bone mineral density; LIHC cis rs11822910 1.000 rs2439448 chr11:57199211 T/C cg00522883 chr11:57194120 SLC43A3 0.68 9.0 0.44 1.63e-17 Platelet distribution width; LIHC cis rs9309473 0.948 rs11884776 chr2:73746923 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.47 -0.33 3.31e-10 Metabolite levels; LIHC cis rs10861342 0.892 rs11112418 chr12:105630463 A/G cg23923672 chr12:105501055 KIAA1033 0.61 6.87 0.35 2.97e-11 IgG glycosylation; LIHC cis rs4407350 0.870 rs131172 chr22:44902759 A/G cg11695653 chr22:44894386 LDOC1L -0.33 -5.72 -0.3 2.36e-8 Intelligence (multi-trait analysis); LIHC cis rs7116495 1.000 rs117372845 chr11:71568849 C/T cg26138937 chr11:71823887 C11orf51 0.69 6.6 0.34 1.58e-10 Severe influenza A (H1N1) infection; LIHC cis rs6840360 1.000 rs6535810 chr4:152592953 C/T cg22705602 chr4:152727874 NA -0.3 -6.46 -0.33 3.5e-10 Intelligence (multi-trait analysis); LIHC cis rs67478160 0.643 rs6576005 chr14:104292369 C/T cg08213375 chr14:104286397 PPP1R13B 0.51 9.66 0.46 1.12e-19 Schizophrenia; LIHC cis rs2274273 0.588 rs7145727 chr14:55847573 G/A cg01864836 chr14:55583639 NA -0.41 -7.46 -0.37 7.09e-13 Protein biomarker; LIHC cis rs17685 0.753 rs869806 chr7:75688623 C/T cg16684958 chr7:75615977 POR 0.52 8.77 0.43 8.8e-17 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7100689 0.646 rs7092237 chr10:82165640 A/G cg01528321 chr10:82214614 TSPAN14 0.65 10.32 0.49 6.33e-22 Post bronchodilator FEV1; LIHC cis rs870825 0.616 rs4610378 chr4:185624220 C/T cg04058563 chr4:185651563 MLF1IP -0.72 -7.4 -0.37 1.03e-12 Blood protein levels; LIHC cis rs7772486 0.790 rs9403756 chr6:146257761 C/G cg13319975 chr6:146136371 FBXO30 0.4 6.39 0.33 5.36e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11628318 0.614 rs8013886 chr14:103117389 A/G cg23461800 chr14:103021989 NA 0.38 5.73 0.3 2.2e-8 Platelet count; LIHC cis rs7914558 1.000 rs11191577 chr10:104902165 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg03116466 chr7:2116512 MAD1L1 -0.37 -6.44 -0.33 4.1e-10 Calcium levels; LIHC cis rs116095464 0.558 rs7714335 chr5:263513 T/C cg22496380 chr5:211416 CCDC127 -1.07 -10.67 -0.5 3.83e-23 Breast cancer; LIHC trans rs75804782 0.521 rs56227677 chr2:239449867 C/T cg01134436 chr17:81009848 B3GNTL1 0.74 6.28 0.32 1.03e-9 Morning vs. evening chronotype;Chronotype; LIHC cis rs9902453 1.000 rs9912741 chr17:28359511 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs4144743 1.000 rs4144746 chr17:45323355 C/G cg18085866 chr17:45331354 ITGB3 -0.59 -8.57 -0.42 3.74e-16 Body mass index; LIHC cis rs2070488 1.000 rs13074025 chr3:38455704 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.66 0.65 4.59e-42 Electrocardiographic conduction measures; LIHC trans rs116095464 0.558 rs59284383 chr5:284525 C/G cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs5753618 0.539 rs4820962 chr22:31689951 A/G cg22777020 chr22:31556080 RNF185 -0.54 -6.23 -0.32 1.37e-9 Colorectal cancer; LIHC cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg23982607 chr1:1823379 GNB1 -0.72 -14.28 -0.61 1.27e-36 Body mass index; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg20626144 chr17:157107 RPH3AL 0.4 6.09 0.31 3.1e-9 Electroencephalogram traits; LIHC cis rs4808199 0.793 rs12459676 chr19:19425141 A/T cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.06 0.36 9.32e-12 Nonalcoholic fatty liver disease; LIHC cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg12463550 chr7:65579703 CRCP 0.69 7.09 0.36 7.75e-12 Diabetic kidney disease; LIHC cis rs4834770 1.000 rs10034579 chr4:120244029 A/C cg09307838 chr4:120376055 NA 0.44 6.56 0.33 2.04e-10 Blood protein levels; LIHC trans rs7618501 0.602 rs2526754 chr3:50125996 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.14 -0.44 5.47e-18 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs9883753 chr3:134247231 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9467773 1.000 rs767471 chr6:26557854 C/T cg09904177 chr6:26538194 HMGN4 0.65 13.78 0.6 1.14e-34 Intelligence (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25008156 chr6:170893875 PDCD2 -0.48 -6.04 -0.31 4.02e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs748404 0.631 rs28702649 chr15:43648629 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.71 0.47 7.38e-20 Lung cancer; LIHC cis rs875971 0.508 rs10253883 chr7:66061138 T/C cg14393609 chr7:65229607 NA -0.35 -5.75 -0.3 2.01e-8 Aortic root size; LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg11494091 chr17:61959527 GH2 0.44 8.14 0.4 7.19e-15 Prudent dietary pattern; LIHC cis rs4975616 0.836 rs460073 chr5:1336459 T/C cg06550200 chr5:1325588 CLPTM1L -0.68 -10.8 -0.5 1.33e-23 Lung cancer; LIHC cis rs151997 0.720 rs152096 chr5:50213850 A/G cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC cis rs2075371 0.830 rs1421478 chr7:133922793 T/A cg20476274 chr7:133979776 SLC35B4 0.65 8.74 0.43 1.05e-16 Mean platelet volume; LIHC cis rs2439831 0.850 rs3736180 chr15:44106624 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.45 0.42 8.7e-16 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07050772 chr17:48423262 XYLT2 -0.42 -6.64 -0.34 1.23e-10 Pancreatic cancer; LIHC trans rs208520 0.955 rs17644076 chr6:67004973 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.66 -7.19 -0.36 4.2e-12 Exhaled nitric oxide output; LIHC trans rs1005277 0.579 rs1614236 chr10:38502996 C/T cg17830980 chr10:43048298 ZNF37B -0.52 -10.13 -0.48 2.99e-21 Extrinsic epigenetic age acceleration; LIHC cis rs801193 1.000 rs7789184 chr7:66210195 A/T cg14393609 chr7:65229607 NA 0.37 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs1707322 1.000 rs4539075 chr1:46358010 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.24 0.32 1.32e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1443512 0.812 rs1975470 chr12:54336841 G/A cg25024717 chr12:54324583 NA -0.31 -6.16 -0.32 2.06e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs9583531 0.689 rs9588247 chr13:111375571 G/T cg15841412 chr13:111365552 ING1 -0.49 -6.05 -0.31 3.78e-9 Coronary artery disease; LIHC cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg11764359 chr7:65958608 NA 0.57 5.95 0.31 6.62e-9 Diabetic kidney disease; LIHC cis rs11608355 0.515 rs7310945 chr12:109946012 G/A cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs243505 0.762 rs10225300 chr7:148502007 G/C cg09806900 chr7:148480153 CUL1 0.44 6.52 0.33 2.48e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs929354 0.707 rs1182445 chr7:157024428 C/G cg17757837 chr7:157058334 UBE3C -0.73 -11.97 -0.54 7.84e-28 Body mass index; LIHC cis rs13108904 0.846 rs4045131 chr4:1228797 A/G cg05665937 chr4:1216051 CTBP1 0.47 6.44 0.33 4.11e-10 Obesity-related traits; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg05861140 chr6:150128134 PCMT1 -0.4 -7.39 -0.37 1.16e-12 Lung cancer; LIHC cis rs6860806 0.507 rs272878 chr5:131671769 C/T cg24060327 chr5:131705240 SLC22A5 0.82 12.89 0.57 2.86e-31 Breast cancer; LIHC cis rs1816752 0.837 rs9318530 chr13:24998557 A/G cg22771759 chr13:24902376 NA -0.29 -5.87 -0.3 1.05e-8 Obesity-related traits; LIHC cis rs875971 0.502 rs2465121 chr7:65621004 A/G cg11764359 chr7:65958608 NA -0.51 -6.95 -0.35 1.91e-11 Aortic root size; LIHC cis rs6831352 0.819 rs1230158 chr4:99990186 T/C cg12011299 chr4:100065546 ADH4 0.52 9.03 0.44 1.26e-17 Alcohol dependence; LIHC cis rs2625529 0.878 rs4777478 chr15:72279085 T/C cg16672083 chr15:72433130 SENP8 -0.3 -5.78 -0.3 1.73e-8 Red blood cell count; LIHC trans rs10242455 0.702 rs112475236 chr7:99044679 A/G cg09045935 chr12:6379348 NA 0.83 6.85 0.35 3.36e-11 Blood metabolite levels; LIHC cis rs7552404 0.924 rs1498317 chr1:76171984 A/C cg10523679 chr1:76189770 ACADM 0.67 9.96 0.47 1.11e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8062405 0.721 rs151181 chr16:28490517 A/G cg07451762 chr16:28383216 NA 0.33 6.18 0.32 1.78e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1707322 0.662 rs11211160 chr1:46146229 T/A cg03146154 chr1:46216737 IPP 0.57 9.76 0.47 4.98e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14839808 chr12:28343774 NA 0.44 6.15 0.32 2.19e-9 Lung function (FEV1/FVC); LIHC cis rs28493229 0.737 rs2288450 chr19:41209177 C/T cg21869046 chr19:41225005 ITPKC 0.5 6.22 0.32 1.43e-9 Kawasaki disease; LIHC cis rs365132 0.905 rs10068703 chr5:176377069 T/A cg16309518 chr5:176445507 NA -0.58 -11.56 -0.53 2.68e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC trans rs1814175 0.585 rs4881661 chr11:50000117 A/G cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs8060686 0.641 rs76595854 chr16:68130233 T/C cg05110241 chr16:68378359 PRMT7 -0.6 -6.77 -0.34 5.6e-11 HDL cholesterol;Metabolic syndrome; LIHC trans rs2727020 0.729 rs4315497 chr11:49214499 G/A cg03929089 chr4:120376271 NA 0.79 13.92 0.6 3.27e-35 Coronary artery disease; LIHC cis rs2404602 0.716 rs67888330 chr15:76752483 A/G cg03037974 chr15:76606532 NA 0.8 16.51 0.67 1.94e-45 Blood metabolite levels; LIHC cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg06481639 chr22:41940642 POLR3H -0.69 -6.76 -0.34 6.08e-11 Vitiligo; LIHC cis rs11792861 0.541 rs838824 chr9:111670707 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.56 -8.26 -0.41 3.15e-15 Menarche (age at onset); LIHC cis rs910316 0.763 rs175490 chr14:75545685 A/G cg08847533 chr14:75593920 NEK9 0.9 18.69 0.71 3.15e-54 Height; LIHC cis rs7044106 0.762 rs1324473 chr9:123404610 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.51 -7.73 -0.39 1.19e-13 Hip circumference adjusted for BMI; LIHC cis rs7772486 0.846 rs1474871 chr6:146406294 G/A cg13319975 chr6:146136371 FBXO30 -0.34 -5.72 -0.3 2.34e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.52 0.33 2.57e-10 Bipolar disorder; LIHC cis rs12908161 0.959 rs34784022 chr15:85231906 T/C cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC cis rs11190604 1.000 rs12219789 chr10:102213778 A/G cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7659604 0.728 rs6852923 chr4:122688324 G/A cg19748678 chr4:122722346 EXOSC9 0.63 10.52 0.49 1.3e-22 Type 2 diabetes; LIHC trans rs6489882 0.902 rs3759376 chr12:113373563 A/G cg10175203 chr3:128143634 NA 0.38 6.19 0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC cis rs9549328 0.800 rs9549617 chr13:113628070 C/A cg00071026 chr13:113650936 MCF2L -0.39 -5.92 -0.31 7.67e-9 Systolic blood pressure; LIHC cis rs2455799 0.613 rs12491914 chr3:15808672 A/C cg12698662 chr3:15914712 MIR563 -0.39 -7.33 -0.37 1.71e-12 Mean platelet volume; LIHC cis rs12594515 1.000 rs56412446 chr15:45996424 A/G cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs7607369 0.759 rs10179708 chr2:219390967 T/A cg02176678 chr2:219576539 TTLL4 -0.55 -7.68 -0.38 1.73e-13 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs9814567 0.752 rs9836401 chr3:134336897 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.56 -8.94 -0.44 2.45e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs17345786 0.861 rs79181492 chr3:101216021 G/A cg12386194 chr3:101231763 SENP7 0.59 7.48 0.38 6.2800000000000005e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs6750795 0.542 rs1797388 chr2:232415981 T/G cg19187155 chr2:232395269 NMUR1 0.49 7.36 0.37 1.36e-12 Height; LIHC cis rs11671005 0.695 rs12972898 chr19:58956888 A/G cg25952890 chr19:58913133 NA 0.67 7.14 0.36 5.76e-12 Mean platelet volume; LIHC cis rs2576037 0.583 rs501062 chr18:44411135 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.94 0.51 4.21e-24 Personality dimensions; LIHC cis rs951366 0.538 rs56276813 chr1:205730573 G/T cg17723122 chr1:205641542 SLC45A3 0.38 5.75 0.3 1.99e-8 Menarche (age at onset); LIHC cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.52 -0.69 1.72e-49 Gut microbiome composition (summer); LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg10096929 chr1:156261403 TMEM79 0.41 6.77 0.34 5.47e-11 Tonsillectomy; LIHC cis rs4819052 0.679 rs2838859 chr21:46684517 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.73 0.39 1.23e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10484885 0.824 rs28372875 chr6:90529343 C/T cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.69 -0.34 9.39e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg05368731 chr17:41323189 NBR1 0.72 12.4 0.56 2.05e-29 Menopause (age at onset); LIHC cis rs10464366 0.544 rs2280667 chr7:39172228 A/C cg15212455 chr7:39170539 POU6F2 0.46 8.24 0.41 3.81e-15 IgG glycosylation; LIHC cis rs9733 0.566 rs72702554 chr1:150678234 A/G cg18016565 chr1:150552671 MCL1 0.58 11.5 0.53 4.36e-26 Tonsillectomy; LIHC cis rs6964587 0.967 rs28594877 chr7:91644070 C/T cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs9916302 0.904 rs11078897 chr17:37415870 C/T cg03013999 chr17:37608204 MED1 0.36 6.13 0.31 2.47e-9 Glomerular filtration rate (creatinine); LIHC cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg11644478 chr21:40555479 PSMG1 0.77 9.68 0.46 9.51e-20 Cognitive function; LIHC cis rs2075165 0.901 rs759329 chr1:156230936 A/G cg08469215 chr1:156261351 TMEM79 0.37 5.9 0.3 8.6e-9 Tonsillectomy; LIHC trans rs2262909 0.962 rs422344 chr19:22230956 C/G cg05197062 chr11:11642011 GALNTL4 0.42 6.05 0.31 3.77e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs34779708 0.966 rs10827493 chr10:35454976 C/T cg03585969 chr10:35415529 CREM 0.86 13.05 0.58 7.33e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs708547 0.836 rs1713997 chr4:57843863 G/C cg14719990 chr4:57843890 C4orf14;POLR2B 0.41 5.75 0.3 2.03e-8 Response to bleomycin (chromatid breaks); LIHC cis rs1865760 0.964 rs3799373 chr6:25929173 A/C cg17691542 chr6:26056736 HIST1H1C 0.41 6.19 0.32 1.74e-9 Height; LIHC cis rs589448 0.867 rs623853 chr12:69753830 G/A cg19645103 chr12:69753606 YEATS4 -0.4 -5.92 -0.3 7.74e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs763121 0.853 rs9607566 chr22:39075434 C/G cg14440974 chr22:39074834 NA -0.45 -7.3 -0.37 2.09e-12 Menopause (age at onset); LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.750 rs2563285 chr5:140126137 T/C cg26395211 chr5:140044315 WDR55 0.39 5.86 0.3 1.08e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs6089584 0.606 rs2144674 chr20:60576579 G/A cg06108461 chr20:60628389 TAF4 -0.54 -7.36 -0.37 1.41e-12 Body mass index; LIHC cis rs4654899 0.758 rs6698462 chr1:21341293 G/C cg08539965 chr1:21396338 EIF4G3 0.33 5.87 0.3 1.04e-8 Superior frontal gyrus grey matter volume; LIHC cis rs7772486 0.754 rs4566902 chr6:146244128 A/G cg13319975 chr6:146136371 FBXO30 0.35 5.78 0.3 1.66e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6714710 0.603 rs11684749 chr2:98420142 G/C cg26665480 chr2:98280029 ACTR1B 0.43 6.11 0.31 2.71e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs5769765 0.825 rs9616780 chr22:50292763 T/C cg02269571 chr22:50332266 NA -0.61 -8.72 -0.43 1.23e-16 Schizophrenia; LIHC trans rs1499614 1.000 rs2659911 chr7:66158420 G/A cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs12986413 0.846 rs12609327 chr19:2183000 A/C cg09261902 chr19:2140048 AP3D1 0.39 6.55 0.33 2.06e-10 Height; LIHC cis rs4975709 0.569 rs2353583 chr5:1858834 G/C cg14773178 chr5:1868261 NA 0.26 6.68 0.34 9.8e-11 Cardiovascular disease risk factors; LIHC cis rs763014 0.932 rs2269560 chr16:682442 A/C cg00802000 chr16:706648 WDR90 -0.38 -6.2 -0.32 1.62e-9 Height; LIHC cis rs2228479 0.850 rs62052711 chr16:89855100 C/A cg00800038 chr16:89945340 TCF25 -0.59 -8.21 -0.41 4.6e-15 Skin colour saturation; LIHC cis rs12464559 0.649 rs12693116 chr2:152623917 A/G cg01189475 chr2:152685088 ARL5A 0.64 7.55 0.38 3.92e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7937890 0.967 rs963212 chr11:14324732 A/G cg02251663 chr11:14281053 SPON1 0.44 6.12 0.31 2.57e-9 Mitochondrial DNA levels; LIHC cis rs12701220 0.894 rs2141274 chr7:1034717 G/A cg26769984 chr7:1090371 C7orf50 0.57 7.31 0.37 1.85e-12 Bronchopulmonary dysplasia; LIHC cis rs10504073 0.584 rs62507177 chr8:49937306 C/A cg00325661 chr8:49890786 NA 0.36 8.0 0.4 1.9e-14 Blood metabolite ratios; LIHC cis rs7618501 0.933 rs1128535 chr3:49866392 C/T cg24110177 chr3:50126178 RBM5 -0.45 -7.05 -0.36 1.01e-11 Intelligence (multi-trait analysis); LIHC cis rs2439831 1.000 rs2439850 chr15:43784854 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.69 0.43 1.5e-16 Lung cancer in ever smokers; LIHC cis rs10170846 0.731 rs10180632 chr2:223526384 G/A cg25565276 chr2:223520875 FARSB 0.63 9.32 0.45 1.52e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs332507 0.789 rs11928787 chr3:124408149 C/T cg05980111 chr3:124395277 KALRN 0.45 6.88 0.35 2.92e-11 Plateletcrit; LIHC cis rs67478160 0.643 rs6575999 chr14:104250609 C/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.62 0.56 3.14e-30 Schizophrenia; LIHC cis rs72781680 0.846 rs72780198 chr2:24014883 T/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg05590025 chr7:65112418 INTS4L2 -0.6 -6.55 -0.33 2.13e-10 Diabetic kidney disease; LIHC trans rs2726453 0.562 rs2713834 chr4:106310520 G/T cg08687137 chr11:62389499 B3GAT3 -0.44 -6.05 -0.31 3.87e-9 Intelligence (multi-trait analysis); LIHC cis rs7212590 0.529 rs60283440 chr17:57994248 T/C cg10252138 chr17:58120427 NA -0.62 -6.61 -0.34 1.45e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs11190604 0.767 rs77769532 chr10:102193646 T/C cg07080220 chr10:102295463 HIF1AN 0.47 6.93 0.35 2.08e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9399135 0.967 rs6919862 chr6:135352443 C/A cg22676075 chr6:135203613 NA 0.39 6.49 0.33 3.07e-10 Red blood cell count; LIHC cis rs9868809 0.881 rs7631574 chr3:48663046 A/G cg07636037 chr3:49044803 WDR6 0.53 6.38 0.33 5.75e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs3008870 0.755 rs4655662 chr1:67416432 T/C cg02640540 chr1:67518911 SLC35D1 0.41 6.36 0.33 6.46e-10 Lymphocyte percentage of white cells; LIHC cis rs7568458 0.684 rs7593969 chr2:85809670 A/G cg02493740 chr2:85810744 VAMP5 0.48 7.91 0.39 3.49e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg02353165 chr6:42928485 GNMT 0.77 11.92 0.54 1.29e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4900538 0.821 rs7012 chr14:102814945 C/T cg18135206 chr14:102964638 TECPR2 -0.69 -10.67 -0.5 4.02e-23 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1552244 0.554 rs59465469 chr3:9990800 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.52 -8.44 -0.42 9.2e-16 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00258694 chr4:56815070 CEP135 -0.45 -6.28 -0.32 1.02e-9 Pancreatic cancer; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.46 -6.61 -0.34 1.51e-10 Lymphocyte counts; LIHC cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg23131131 chr22:24373011 LOC391322 0.63 8.76 0.43 9.5e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.83 7.89 0.39 3.99e-14 Platelet count; LIHC cis rs875971 0.545 rs73378304 chr7:65640747 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.33 6.54 0.33 2.24e-10 Aortic root size; LIHC cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg00166722 chr3:10149974 C3orf24 0.48 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC cis rs2153535 0.505 rs1737583 chr6:8536812 G/A cg07606381 chr6:8435919 SLC35B3 0.78 11.18 0.52 5.97e-25 Motion sickness; LIHC cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs7568498 0.517 rs11678856 chr2:161925443 C/T cg22496339 chr2:162101262 NA -0.54 -7.33 -0.37 1.65e-12 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC cis rs6430585 0.528 rs12464050 chr2:136663110 G/T cg15123519 chr2:136567270 LCT -0.36 -5.81 -0.3 1.45e-8 Corneal structure; LIHC cis rs986417 0.818 rs10139251 chr14:60959958 A/C cg27398547 chr14:60952738 C14orf39 0.77 9.25 0.45 2.58e-18 Gut microbiota (bacterial taxa); LIHC cis rs311392 0.902 rs438437 chr8:55094187 G/C cg11783602 chr8:55087084 NA -0.31 -6.04 -0.31 4e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs9303401 0.527 rs12939313 chr17:56755616 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.94 11.34 0.52 1.68e-25 Cognitive test performance; LIHC cis rs611744 0.967 rs628843 chr8:109196115 C/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs1707322 0.752 rs7541962 chr1:46235117 G/A cg03146154 chr1:46216737 IPP 0.56 8.92 0.43 2.86e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg17246404 chr3:65365162 MAGI1 0.38 6.19 0.32 1.71e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs875971 0.545 rs12671152 chr7:65776127 G/T cg11764359 chr7:65958608 NA 0.58 7.7 0.38 1.46e-13 Aortic root size; LIHC cis rs11864453 0.514 rs2269918 chr16:72134831 C/A cg01557791 chr16:72042693 DHODH -0.43 -7.11 -0.36 6.79e-12 Fibrinogen levels; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC cis rs546131 0.928 rs516228 chr11:34838823 C/T cg06937548 chr11:34938143 PDHX;APIP 0.58 7.81 0.39 7.2e-14 Lung disease severity in cystic fibrosis; LIHC cis rs4555082 0.834 rs2816624 chr14:105733909 A/G cg13114125 chr14:105738426 BRF1 -0.74 -9.66 -0.46 1.07e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs7647973 1.000 rs6446262 chr3:49401153 T/C cg07636037 chr3:49044803 WDR6 0.52 6.22 0.32 1.43e-9 Menarche (age at onset); LIHC cis rs6840360 0.593 rs1877185 chr4:152690348 C/T cg22705602 chr4:152727874 NA -0.39 -8.32 -0.41 2.19e-15 Intelligence (multi-trait analysis); LIHC cis rs7503168 1.000 rs9894057 chr17:33889923 G/A cg20932281 chr17:33905541 PEX12 0.58 7.34 0.37 1.61e-12 Plateletcrit; LIHC cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs72781680 0.665 rs72788298 chr2:24104293 T/C cg08917208 chr2:24149416 ATAD2B 0.64 6.55 0.33 2.09e-10 Lymphocyte counts; LIHC cis rs9814567 1.000 rs9856693 chr3:134306913 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2952156 0.920 rs2517957 chr17:37838716 G/A cg00129232 chr17:37814104 STARD3 -0.56 -10.51 -0.49 1.47e-22 Asthma; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22997252 chr11:11643842 GALNTL4 0.49 6.39 0.33 5.47e-10 Lung function (FEV1/FVC); LIHC cis rs367615 0.704 rs11747622 chr5:108844720 G/A cg17395555 chr5:108820864 NA 0.4 8.8 0.43 7.12e-17 Colorectal cancer (SNP x SNP interaction); LIHC cis rs10876993 0.928 rs1628552 chr12:58082142 C/T cg15848620 chr12:58087721 OS9 -0.58 -8.01 -0.4 1.77e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs6750047 0.649 rs4670231 chr2:38267836 T/G cg07380506 chr2:38303506 CYP1B1 0.5 5.88 0.3 9.77e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs10751667 0.643 rs10902257 chr11:973577 T/C cg10932868 chr11:921992 NA 0.4 7.62 0.38 2.53e-13 Alzheimer's disease (late onset); LIHC cis rs1799949 1.000 rs8077486 chr17:41212805 C/T cg23758822 chr17:41437982 NA 0.89 16.21 0.66 3.09e-44 Menopause (age at onset); LIHC cis rs2404602 0.684 rs12591622 chr15:76930655 A/T cg23625390 chr15:77176239 SCAPER -0.53 -8.67 -0.42 1.73e-16 Blood metabolite levels; LIHC cis rs11958404 0.932 rs72816580 chr5:157432221 A/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs6860806 0.507 rs635620 chr5:131720263 A/G cg24060327 chr5:131705240 SLC22A5 0.79 12.39 0.56 2.31e-29 Breast cancer; LIHC cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg07308232 chr7:1071921 C7orf50 -0.47 -7.51 -0.38 5.32e-13 Longevity;Endometriosis; LIHC cis rs1185460 0.547 rs667584 chr11:118911544 C/T cg23280166 chr11:118938394 VPS11 -0.45 -6.13 -0.31 2.36e-9 Coronary artery disease; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg06873352 chr17:61820015 STRADA 0.72 12.5 0.56 9.04e-30 Prudent dietary pattern; LIHC cis rs295140 0.506 rs295136 chr2:201141002 G/C cg23649088 chr2:200775458 C2orf69 0.45 6.15 0.32 2.13e-9 QT interval; LIHC trans rs1814175 0.616 rs10769644 chr11:49987676 C/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs4665809 0.816 rs2384359 chr2:26371364 T/C cg04944784 chr2:26401820 FAM59B -0.74 -9.29 -0.45 1.79e-18 Gut microbiome composition (summer); LIHC cis rs6665290 0.935 rs6704144 chr1:227201030 C/G cg10327440 chr1:227177885 CDC42BPA -1.11 -27.37 -0.83 3.73e-88 Myeloid white cell count; LIHC cis rs6543140 0.601 rs6543135 chr2:103062406 C/T cg09003973 chr2:102972529 NA 0.82 8.47 0.42 7.44e-16 Blood protein levels; LIHC cis rs4808199 0.689 rs12979148 chr19:19406869 T/C cg21559469 chr19:19431446 KIAA0892;SF4 0.49 5.85 0.3 1.12e-8 Nonalcoholic fatty liver disease; LIHC cis rs4665809 0.878 rs4665826 chr2:26367503 A/T cg26119090 chr2:26468346 HADHA;HADHB 0.83 10.66 0.5 4.38e-23 Gut microbiome composition (summer); LIHC cis rs2204008 0.837 rs11169157 chr12:37980047 T/C cg26384229 chr12:38710491 ALG10B 0.79 10.16 0.48 2.24e-21 Bladder cancer; LIHC cis rs1448094 0.512 rs7308229 chr12:86239849 A/T cg02569458 chr12:86230093 RASSF9 -0.46 -6.16 -0.32 2.01e-9 Major depressive disorder; LIHC cis rs17152411 0.652 rs4962412 chr10:126654643 C/G cg07906193 chr10:126599966 NA -0.31 -6.16 -0.32 2.02e-9 Height; LIHC cis rs2075371 0.637 rs2544165 chr7:133920443 A/G cg20476274 chr7:133979776 SLC35B4 -0.68 -11.04 -0.51 1.92e-24 Mean platelet volume; LIHC cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg10360323 chr17:41437877 NA 0.41 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs7546668 1.000 rs4646100 chr1:15820041 C/T cg11706911 chr1:15910989 AGMAT 0.46 7.05 0.36 1.01e-11 Glomerular filtration rate (creatinine); LIHC cis rs881375 0.654 rs10760126 chr9:123662618 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.63 0.34 1.3e-10 Rheumatoid arthritis; LIHC cis rs9914988 0.943 rs4794838 chr17:27131095 T/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.86 -0.35 3.23e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7116495 1.000 rs2298456 chr11:71730715 A/T cg26138937 chr11:71823887 C11orf51 0.8 8.21 0.41 4.64e-15 Severe influenza A (H1N1) infection; LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg01420254 chr6:26195488 NA 0.51 5.77 0.3 1.77e-8 Gout;Renal underexcretion gout; LIHC cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg14676711 chr18:48405181 ME2 -0.43 -6.18 -0.32 1.79e-9 Calcium levels; LIHC cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg11890956 chr21:40555474 PSMG1 -0.49 -8.25 -0.41 3.39e-15 Menarche (age at onset); LIHC cis rs2115536 0.692 rs6495450 chr15:80162499 C/A cg00225070 chr15:80189496 MTHFS 0.46 7.46 0.37 7.09e-13 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs208520 0.526 rs2881644 chr6:66803535 A/C cg07460842 chr6:66804631 NA 1.02 19.65 0.73 4.3e-58 Exhaled nitric oxide output; LIHC cis rs8016982 0.633 rs8015423 chr14:81719357 C/T cg01989461 chr14:81687754 GTF2A1 0.69 14.0 0.6 1.64e-35 Schizophrenia; LIHC cis rs7072216 0.763 rs3814140 chr10:100170762 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs1048238 0.506 rs56352596 chr1:16297592 G/A cg00529422 chr1:16285251 ZBTB17 -0.35 -6.86 -0.35 3.22e-11 Systolic blood pressure; LIHC cis rs1707322 0.686 rs1547924 chr1:46085112 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.8 0.39 7.81e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7613875 0.620 rs7634441 chr3:50071677 G/A cg05623727 chr3:50126028 RBM5 -0.34 -5.83 -0.3 1.27e-8 Body mass index; LIHC trans rs61931739 0.500 rs7488438 chr12:34531359 G/T cg26384229 chr12:38710491 ALG10B 0.78 9.5 0.46 3.88e-19 Morning vs. evening chronotype; LIHC cis rs6570726 0.755 rs2103633 chr6:145894021 C/T cg23711669 chr6:146136114 FBXO30 0.71 12.68 0.57 1.87e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs6430585 0.528 rs309158 chr2:136680534 A/G cg07169764 chr2:136633963 MCM6 0.98 15.35 0.64 8.11e-41 Corneal structure; LIHC cis rs1997103 0.954 rs9649854 chr7:55410213 G/A cg17469321 chr7:55412551 NA 0.47 6.98 0.35 1.56e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6912958 0.967 rs9450688 chr6:88159276 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.15 -0.36 5.32e-12 Monocyte percentage of white cells; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg17158414 chr2:27665306 KRTCAP3 -0.46 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg02951883 chr7:2050386 MAD1L1 -0.69 -11.38 -0.52 1.12e-25 Bipolar disorder and schizophrenia; LIHC trans rs10506458 1.000 rs73128779 chr12:63441852 T/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.42 -0.49 2.92e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.29 -0.45 1.85e-18 Bipolar disorder; LIHC trans rs11088226 0.681 rs2833895 chr21:33929802 G/A cg09050820 chr6:167586206 TCP10L2 0.85 13.42 0.59 2.73e-33 Gastritis; LIHC cis rs6840360 0.571 rs6811676 chr4:152562726 T/C cg22705602 chr4:152727874 NA -0.32 -6.21 -0.32 1.55e-9 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg20102877 chr2:27665638 KRTCAP3 -0.44 -6.07 -0.31 3.39e-9 Total body bone mineral density; LIHC cis rs8180040 0.768 rs11915074 chr3:47309757 A/T cg16586182 chr3:47516702 SCAP 0.52 9.17 0.44 4.62e-18 Colorectal cancer; LIHC trans rs1814175 0.746 rs10839429 chr11:49906845 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs74233809 1.000 rs11191558 chr10:104864678 G/A cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.43e-9 Birth weight; LIHC cis rs7703051 0.520 rs13354746 chr5:74619132 C/T cg19683494 chr5:74908142 NA 0.7 9.66 0.46 1.08e-19 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs796364 1.000 rs1704186 chr2:200769539 A/C cg23649088 chr2:200775458 C2orf69 0.5 6.01 0.31 4.85e-9 Schizophrenia; LIHC trans rs875971 0.545 rs2420456 chr7:65745606 T/G cg26939375 chr7:64535504 NA 0.41 6.51 0.33 2.74e-10 Aortic root size; LIHC cis rs546131 0.642 rs1594426 chr11:34833459 T/C cg11058730 chr11:34937778 PDHX;APIP -0.55 -6.59 -0.34 1.66e-10 Lung disease severity in cystic fibrosis; LIHC cis rs10870270 0.956 rs67378218 chr10:133752420 A/C cg26149184 chr10:133730230 NA 0.46 7.32 0.37 1.8e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs2732480 0.557 rs2409004 chr12:48721451 T/C cg21466736 chr12:48725269 NA -0.73 -11.46 -0.53 6.2e-26 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs9733 0.544 rs2867302 chr1:150653650 T/C cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Tonsillectomy; LIHC cis rs17384381 1.000 rs12133722 chr1:85873237 C/T cg16011679 chr1:85725395 C1orf52 0.83 8.75 0.43 9.79e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 1.000 rs12060274 chr1:46291062 G/T cg03146154 chr1:46216737 IPP 0.48 7.8 0.39 7.74e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07258852 chr11:94227583 ANKRD49;MRE11A -0.39 -6.21 -0.32 1.55e-9 Cognitive function; LIHC cis rs12497850 0.931 rs4072859 chr3:49032205 G/C cg07636037 chr3:49044803 WDR6 0.94 16.47 0.67 2.75e-45 Parkinson's disease; LIHC cis rs9549367 0.789 rs2025247 chr13:113882564 C/G cg18105134 chr13:113819100 PROZ -0.67 -11.63 -0.53 1.39e-26 Platelet distribution width; LIHC trans rs4566357 0.595 rs10206912 chr2:227921095 A/T cg16088116 chr21:44841560 SIK1 -0.42 -6.51 -0.33 2.73e-10 Coronary artery disease; LIHC cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg23978390 chr7:1156363 C7orf50 0.5 7.28 0.37 2.3e-12 Longevity;Endometriosis; LIHC cis rs17685 0.712 rs28506984 chr7:75763484 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg24209194 chr3:40518798 ZNF619 0.64 9.75 0.47 5.46e-20 Renal cell carcinoma; LIHC cis rs796364 0.715 rs77089299 chr2:201116853 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.77 -7.22 -0.36 3.39e-12 Schizophrenia; LIHC cis rs67478160 0.643 rs12878868 chr14:104233725 G/A cg24130564 chr14:104152367 KLC1 -0.35 -5.83 -0.3 1.31e-8 Schizophrenia; LIHC cis rs679087 0.932 rs7312697 chr12:29933069 T/C cg14258853 chr12:29935411 TMTC1 0.48 7.82 0.39 6.42e-14 Schizophrenia; LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg09033563 chr22:24373618 LOC391322 -0.44 -6.01 -0.31 4.68e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9443189 0.526 rs9359124 chr6:76200514 G/A cg01950844 chr6:76311363 SENP6 0.89 10.14 0.48 2.69e-21 Prostate cancer; LIHC trans rs11098499 0.954 rs6849561 chr4:120409694 C/G cg25214090 chr10:38739885 LOC399744 -0.57 -9.15 -0.44 5.41e-18 Corneal astigmatism; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg14027857 chr1:208136797 NA 0.64 8.04 0.4 1.53e-14 Hepatitis; LIHC trans rs2727020 0.530 rs7113153 chr11:49457957 G/A cg03929089 chr4:120376271 NA -0.67 -9.73 -0.47 6.61e-20 Coronary artery disease; LIHC cis rs9733 0.566 rs112967224 chr1:150677263 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.1e-9 Tonsillectomy; LIHC cis rs892961 0.720 rs103458 chr17:75416031 A/G cg01320579 chr17:75405842 SEPT9 0.55 7.31 0.37 1.96e-12 Airflow obstruction; LIHC cis rs9858542 1.000 rs9823546 chr3:49705512 T/A cg03060546 chr3:49711283 APEH -0.62 -8.41 -0.41 1.1e-15 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.64e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14510374 chr3:50365322 TUSC2 0.5 6.41 0.33 4.94e-10 Lung function (FEV1/FVC); LIHC trans rs5756813 0.635 rs4820301 chr22:38126364 G/A cg19894588 chr14:64061835 NA -0.61 -7.84 -0.39 5.74e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7187994 0.895 rs12598223 chr16:84783873 A/G cg07647771 chr16:84786436 USP10 -0.33 -6.66 -0.34 1.12e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg19318889 chr4:1322082 MAEA 0.43 5.95 0.31 6.65e-9 Obesity-related traits; LIHC cis rs2839186 0.605 rs2839170 chr21:47671305 A/G cg09417038 chr21:47716443 C21orf57 -0.55 -8.31 -0.41 2.33e-15 Testicular germ cell tumor; LIHC cis rs7586673 1.000 rs16845584 chr2:161923830 C/T cg21518248 chr2:162101506 NA -0.39 -5.87 -0.3 1.05e-8 Intelligence (multi-trait analysis); LIHC cis rs2073499 0.935 rs2526400 chr3:50186948 A/G cg24110177 chr3:50126178 RBM5 0.52 6.04 0.31 3.98e-9 Schizophrenia; LIHC cis rs12701220 0.655 rs10241018 chr7:1144774 G/C cg09177884 chr7:1199841 ZFAND2A -0.54 -6.21 -0.32 1.56e-9 Bronchopulmonary dysplasia; LIHC cis rs9948 0.786 rs62156231 chr2:97425603 G/A cg01990225 chr2:97406019 LMAN2L -0.72 -6.26 -0.32 1.14e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs10924970 0.601 rs2803847 chr1:235503611 C/G cg26050004 chr1:235667680 B3GALNT2 0.39 5.78 0.3 1.72e-8 Asthma; LIHC cis rs11958404 0.932 rs72816550 chr5:157418457 A/T cg05962755 chr5:157440814 NA 0.91 10.22 0.48 1.37e-21 IgG glycosylation; LIHC cis rs9814567 1.000 rs13096604 chr3:134250099 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs12406019 0.510 rs2025614 chr1:78618151 G/A cg20826526 chr3:156266748 SSR3 -0.64 -10.8 -0.5 1.37e-23 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8062405 1.000 rs2008514 chr16:28825605 A/G cg07451762 chr16:28383216 NA -0.34 -6.54 -0.33 2.19e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9790314 1.000 rs4597724 chr3:160963110 A/G cg03342759 chr3:160939853 NMD3 -0.7 -8.6 -0.42 2.9e-16 Morning vs. evening chronotype; LIHC cis rs16858210 0.520 rs34190894 chr3:183550412 A/T cg25686905 chr3:183603175 PARL -0.45 -7.33 -0.37 1.69e-12 Menopause (age at onset); LIHC cis rs7542091 0.637 rs9429826 chr1:210052146 G/A cg23283495 chr1:209979779 IRF6 0.34 5.75 0.3 1.95e-8 Monobrow; LIHC cis rs6750047 0.771 rs2855658 chr2:38296890 T/C cg07380506 chr2:38303506 CYP1B1 0.6 7.72 0.39 1.27e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs9649213 0.593 rs3801255 chr7:98000929 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.0 -0.31 5.07e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.77 -0.3 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs7618501 0.933 rs3811695 chr3:49761613 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg24642844 chr7:1081250 C7orf50 -0.92 -9.11 -0.44 7.03e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10508774 1.000 rs72795556 chr10:32868840 C/G cg01819863 chr10:32635814 EPC1 0.65 6.01 0.31 4.73e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6570726 0.791 rs12208812 chr6:145900924 T/G cg13319975 chr6:146136371 FBXO30 -0.42 -6.66 -0.34 1.11e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs801193 1.000 rs62466794 chr7:66191579 G/A cg18876405 chr7:65276391 NA 0.43 7.48 0.37 6.44e-13 Aortic root size; LIHC cis rs2302190 0.882 rs7221464 chr17:56552353 A/T cg12560992 chr17:57184187 TRIM37 0.71 8.91 0.43 3.09e-17 Vitamin D levels; LIHC cis rs9837602 0.507 rs6803204 chr3:99680874 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.8 -0.3 1.48e-8 Breast cancer; LIHC cis rs9494145 0.680 rs4895441 chr6:135426573 C/T cg22676075 chr6:135203613 NA -0.42 -6.05 -0.31 3.83e-9 Mean platelet volume;Platelet count;Fetal hemoglobin levels in sickle cell anemia;Red blood cell traits; LIHC cis rs7980687 0.638 rs7299943 chr12:123593485 A/T cg00376283 chr12:123451042 ABCB9 0.59 7.8 0.39 7.7e-14 Height;Educational attainment;Head circumference (infant); LIHC cis rs11711311 1.000 rs11711311 chr3:113430599 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.07 -0.36 8.56e-12 IgG glycosylation; LIHC trans rs7618501 0.699 rs2681780 chr3:49897830 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.6 9.42 0.45 6.81e-19 Intelligence (multi-trait analysis); LIHC cis rs6547741 1.000 rs13026621 chr2:27807624 G/A cg27432699 chr2:27873401 GPN1 0.72 11.61 0.53 1.73e-26 Oral cavity cancer; LIHC cis rs1059312 1.000 rs1059312 chr12:129278864 A/G cg09035930 chr12:129282057 SLC15A4 -0.66 -12.31 -0.55 4.29e-29 Systemic lupus erythematosus; LIHC cis rs611744 0.647 rs13280487 chr8:109270263 G/C cg18478394 chr8:109455254 TTC35 0.41 7.2 0.36 3.95e-12 Dupuytren's disease; LIHC cis rs7044106 1.000 rs7044106 chr9:123494062 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.55 7.43 0.37 8.88e-13 Hip circumference adjusted for BMI; LIHC cis rs9325144 0.600 rs12227663 chr12:38734922 C/T cg26384229 chr12:38710491 ALG10B -0.56 -7.67 -0.38 1.81e-13 Morning vs. evening chronotype; LIHC cis rs244731 0.959 rs3105419 chr5:176551396 G/C cg16006841 chr5:176797999 RGS14 0.62 6.0 0.31 5.09e-9 Urate levels in lean individuals; LIHC cis rs644799 1.000 rs494829 chr11:95571750 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.61 0.46 1.6e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs240764 0.817 rs239247 chr6:101088350 T/C cg09795085 chr6:101329169 ASCC3 0.51 7.14 0.36 5.7e-12 Neuroticism; LIHC cis rs6430585 0.527 rs62168792 chr2:136415217 A/G cg07169764 chr2:136633963 MCM6 0.68 8.69 0.43 1.55e-16 Corneal structure; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg02592271 chr2:27665507 KRTCAP3 -0.46 -6.41 -0.33 4.78e-10 Total body bone mineral density; LIHC cis rs3772130 0.545 rs7340674 chr3:121574215 T/C cg20356878 chr3:121714668 ILDR1 0.35 5.89 0.3 9.06e-9 Cognitive performance; LIHC cis rs17401966 0.858 rs61778404 chr1:10432879 A/G cg15208524 chr1:10270712 KIF1B 0.41 6.03 0.31 4.19e-9 Hepatocellular carcinoma; LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg14393609 chr7:65229607 NA -0.39 -6.63 -0.34 1.28e-10 Calcium levels; LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg18306943 chr3:40428807 ENTPD3 0.42 7.33 0.37 1.71e-12 Renal cell carcinoma; LIHC cis rs7188697 0.848 rs40187 chr16:58556566 T/C cg02549819 chr16:58548995 SETD6 -0.46 -7.27 -0.37 2.47e-12 QT interval; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04180460 chr3:41240962 CTNNB1 0.37 6.12 0.31 2.5e-9 Cognitive function; LIHC cis rs782590 0.683 rs782633 chr2:55898203 A/G cg18811423 chr2:55921094 PNPT1 0.88 14.01 0.6 1.47e-35 Metabolic syndrome; LIHC cis rs10752881 1.000 rs10797813 chr1:182989366 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.41 0.49 3.07e-22 Colorectal cancer; LIHC cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg09033563 chr22:24373618 LOC391322 -0.47 -6.48 -0.33 3.27e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs796364 0.806 rs10931887 chr2:200968905 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.75 -8.36 -0.41 1.57e-15 Schizophrenia; LIHC cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg07308232 chr7:1071921 C7orf50 -0.54 -9.0 -0.44 1.62e-17 Longevity;Endometriosis; LIHC cis rs7592578 0.771 rs12052514 chr2:191378170 C/T cg27211696 chr2:191398769 TMEM194B -0.61 -8.17 -0.4 6.17e-15 Diastolic blood pressure; LIHC cis rs8072548 1 rs8072548 chr17:38164025 T/G cg17344932 chr17:38183730 MED24;SNORD124 -0.64 -11.61 -0.53 1.76e-26 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg11225849 chr1:211500348 TRAF5 -0.46 -6.61 -0.34 1.51e-10 Alopecia areata; LIHC cis rs6752107 0.901 rs10206299 chr2:234146271 G/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.52 7.81 0.39 7.01e-14 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7223966 0.584 rs76957877 chr17:61621330 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 5.83 0.3 1.25e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs151997 1.000 rs152803 chr5:50212120 C/T cg06027927 chr5:50259733 NA 0.58 7.86 0.39 5.18e-14 Callous-unemotional behaviour; LIHC cis rs5769765 0.837 rs7284417 chr22:50314346 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.67 -8.63 -0.42 2.31e-16 Schizophrenia; LIHC cis rs6952808 0.782 rs4236271 chr7:1881369 C/T cg20295408 chr7:1910781 MAD1L1 -0.48 -7.05 -0.36 9.71e-12 Bipolar disorder and schizophrenia; LIHC cis rs875971 1.000 rs778722 chr7:65844828 T/C cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs10752881 1.000 rs10797810 chr1:182980950 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs2204008 0.665 rs11495668 chr12:38221018 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.75 0.5 2.1e-23 Bladder cancer; LIHC cis rs787274 1.000 rs9409123 chr9:115507165 G/A cg13803584 chr9:115635662 SNX30 0.61 6.48 0.33 3.19e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs61931739 0.500 rs7963282 chr12:34535255 A/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg12143784 chr7:64541923 NA 0.37 6.42 0.33 4.55e-10 Calcium levels; LIHC cis rs2153535 0.541 rs9328477 chr6:8519109 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.79 0.54 3.68e-27 Motion sickness; LIHC cis rs12220238 0.915 rs11001014 chr10:76128832 A/G cg19889307 chr10:75911429 ADK;AP3M1 -0.63 -6.12 -0.31 2.55e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs244293 0.831 rs2111097 chr17:53090474 A/C cg19360675 chr17:53046073 COX11;STXBP4 0.51 7.64 0.38 2.27e-13 Menarche (age at onset); LIHC cis rs4631830 0.869 rs11006207 chr10:51538176 T/C cg20129853 chr10:51489980 NA -0.4 -8.66 -0.42 1.92e-16 Prostate-specific antigen levels; LIHC cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg14004847 chr7:1930337 MAD1L1 -0.49 -7.05 -0.36 9.78e-12 Bipolar disorder and schizophrenia; LIHC cis rs10751667 1.000 rs11246359 chr11:967943 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.47 0.53 5.46e-26 Alzheimer's disease (late onset); LIHC cis rs1707322 1.000 rs7517560 chr1:46425943 A/G cg03146154 chr1:46216737 IPP 0.48 7.86 0.39 4.97e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9733 0.596 rs1336898 chr1:150665050 G/A cg17724175 chr1:150552817 MCL1 0.48 9.72 0.47 7.13e-20 Tonsillectomy; LIHC cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg24549020 chr5:56110836 MAP3K1 0.5 6.41 0.33 4.95e-10 Initial pursuit acceleration; LIHC cis rs9457247 0.765 rs9459849 chr6:167444160 G/T cg12798992 chr6:167411361 FGFR1OP 0.48 7.18 0.36 4.3e-12 Crohn's disease; LIHC cis rs8067354 0.574 rs1292033 chr17:57990597 A/T cg13753209 chr17:57696993 CLTC 0.7 10.48 0.49 1.74e-22 Hemoglobin concentration; LIHC cis rs9640161 0.659 rs59572505 chr7:150014986 C/T cg10018233 chr7:150070692 REPIN1 0.5 8.5 0.42 6.03e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs7587476 0.906 rs17487792 chr2:215643500 A/G cg04004882 chr2:215674386 BARD1 -0.51 -6.28 -0.32 1.03e-9 Neuroblastoma; LIHC cis rs1728785 1.000 rs4783653 chr16:68562815 C/T cg02972257 chr16:68554789 NA -0.52 -6.08 -0.31 3.26e-9 Ulcerative colitis; LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg12419862 chr22:24373484 LOC391322 -0.45 -6.41 -0.33 4.85e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1799949 0.965 rs9646413 chr17:41426157 A/G cg23758822 chr17:41437982 NA 0.92 16.51 0.67 1.87e-45 Menopause (age at onset); LIHC cis rs10736390 0.640 rs10888858 chr1:55108978 A/G cg01517571 chr1:55089959 ACOT11;FAM151A -0.7 -13.68 -0.59 2.91e-34 Survival in pancreatic cancer; LIHC cis rs2991971 0.776 rs12139364 chr1:45890155 T/C cg24296786 chr1:45957014 TESK2 0.52 8.03 0.4 1.62e-14 High light scatter reticulocyte count; LIHC cis rs6456156 0.586 rs6456150 chr6:167468922 A/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.62 -0.42 2.5e-16 Primary biliary cholangitis; LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.94 19.79 0.73 1.18e-58 Height; LIHC trans rs9951602 0.512 rs4799247 chr18:76653449 G/A cg02800362 chr5:177631904 HNRNPAB 0.66 10.52 0.49 1.33e-22 Obesity-related traits; LIHC cis rs769267 0.930 rs6511038 chr19:19607564 A/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.87 0.3 1.05e-8 Tonsillectomy; LIHC cis rs12474201 0.963 rs3829835 chr2:46925789 C/T cg06386533 chr2:46925753 SOCS5 0.72 8.07 0.4 1.17e-14 Height; LIHC cis rs9549367 0.789 rs9549715 chr13:113908240 G/C cg18105134 chr13:113819100 PROZ -0.67 -11.47 -0.53 5.57e-26 Platelet distribution width; LIHC cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg07424592 chr7:64974309 NA 0.81 9.2 0.45 3.52e-18 Diabetic kidney disease; LIHC cis rs9503598 0.502 rs4518545 chr6:3433890 T/A cg00476032 chr6:3446245 SLC22A23 -0.32 -5.8 -0.3 1.52e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs11644362 1.000 rs35972357 chr16:12987664 C/T cg06890432 chr16:12997467 SHISA9 -0.4 -6.77 -0.34 5.6e-11 Positive affect;Subjective well-being; LIHC cis rs8084351 0.539 rs9947905 chr18:50623076 G/A cg24270629 chr18:50823537 DCC 0.43 6.48 0.33 3.2e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06438056 chr1:33502433 AK2 0.46 7.11 0.36 7.01e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.01 0.31 4.83e-9 Menopause (age at onset); LIHC cis rs2303759 0.515 rs2334867 chr19:49788205 C/T cg22307029 chr19:49891270 CCDC155 -0.56 -8.56 -0.42 3.99e-16 Multiple sclerosis; LIHC cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.89 -12.82 -0.57 5.53e-31 Alzheimer's disease; LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.712 rs9800948 chr7:75810473 A/G cg04592579 chr7:75616294 TMEM120A 0.38 6.58 0.34 1.73e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1552244 0.816 rs17050701 chr3:10041554 A/G cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs9612 1.000 rs3786954 chr19:44272346 A/G cg08581076 chr19:44259116 C19orf61 0.59 7.35 0.37 1.51e-12 Exhaled nitric oxide output; LIHC cis rs34779708 0.931 rs11010077 chr10:35328088 C/T cg03585969 chr10:35415529 CREM -0.76 -11.16 -0.52 7.14e-25 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2274273 0.905 rs8007620 chr14:55586587 T/C cg01864836 chr14:55583639 NA -0.39 -7.19 -0.36 4.22e-12 Protein biomarker; LIHC cis rs748404 0.660 rs694725 chr15:43756210 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.94 0.39 2.95e-14 Lung cancer; LIHC cis rs12744310 1.000 rs12034357 chr1:41768229 G/A cg03962019 chr1:41807865 NA 0.4 6.49 0.33 3.01e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11711311 1.000 rs9863050 chr3:113508888 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -6.96 -0.35 1.75e-11 IgG glycosylation; LIHC cis rs8017423 0.630 rs4904678 chr14:90821670 T/C cg04374321 chr14:90722782 PSMC1 -0.49 -7.27 -0.37 2.46e-12 Mortality in heart failure; LIHC cis rs600806 0.778 rs11101960 chr1:110008778 C/T cg16275483 chr1:110013120 SYPL2 -0.49 -6.18 -0.32 1.8e-9 Intelligence (multi-trait analysis); LIHC cis rs2806561 0.704 rs856510 chr1:23524407 A/C cg19743168 chr1:23544995 NA 0.38 6.27 0.32 1.07e-9 Height; LIHC cis rs2072499 0.966 rs2853641 chr1:156181770 A/G cg24450063 chr1:156163899 SLC25A44 0.88 15.98 0.65 2.42e-43 Testicular germ cell tumor; LIHC cis rs17685 0.753 rs10476 chr7:75696420 C/T cg16684958 chr7:75615977 POR -0.5 -8.47 -0.42 7.27e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs919433 0.680 rs6434930 chr2:198369370 A/G cg03934865 chr2:198174659 NA 0.53 8.29 0.41 2.61e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.538 rs3785493 chr17:56472119 G/T cg10487724 chr17:56770010 TEX14;RAD51C -0.93 -12.21 -0.55 1.04e-28 Cognitive test performance; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09747232 chr8:103827049 NA 0.4 6.17 0.32 1.96e-9 Cognitive function; LIHC trans rs11039798 0.764 rs7294013 chr11:48762416 G/A cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs2336384 1.000 rs7551874 chr1:12048130 A/G cg13216073 chr1:12042593 MFN2 0.38 5.73 0.3 2.2e-8 Platelet count; LIHC cis rs6495122 0.651 rs11636952 chr15:75114322 T/C cg14664628 chr15:75095509 CSK -0.72 -12.18 -0.55 1.33e-28 Caffeine consumption;Diastolic blood pressure;Coffee consumption; LIHC trans rs916888 0.821 rs70602 chr17:44859715 T/C cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs8180040 0.966 rs6787422 chr3:47418509 G/T cg27129171 chr3:47204927 SETD2 0.57 9.8 0.47 3.68e-20 Colorectal cancer; LIHC cis rs8072100 0.967 rs11871606 chr17:45732774 G/T cg08085267 chr17:45401833 C17orf57 0.4 5.98 0.31 5.67e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs892961 0.899 rs7222532 chr17:75413302 G/C cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC trans rs1814175 0.817 rs80244685 chr11:49763292 C/A cg15704280 chr7:45808275 SEPT13 -0.94 -19.47 -0.73 2.3e-57 Height; LIHC cis rs7959452 0.590 rs11177644 chr12:69785748 A/G cg14784868 chr12:69753453 YEATS4 0.94 20.33 0.74 8.36e-61 Blood protein levels; LIHC cis rs7945705 0.935 rs2653567 chr11:8889630 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -9.22 -0.45 3.18e-18 Hemoglobin concentration; LIHC cis rs1348850 0.958 rs10497501 chr2:178462299 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.25 0.52 3.44e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg15670579 chr15:102264312 TARSL2 -0.5 -7.36 -0.37 1.41e-12 Immature fraction of reticulocytes; LIHC cis rs11864453 0.611 rs1050361 chr16:72130203 C/G cg01557791 chr16:72042693 DHODH -0.43 -7.15 -0.36 5.22e-12 Fibrinogen levels; LIHC cis rs8027181 1.000 rs7166595 chr15:73094204 A/G cg25632853 chr15:73088954 NA 0.38 6.41 0.33 4.89e-10 Triglyceride levels; LIHC cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg07424592 chr7:64974309 NA -0.8 -9.08 -0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs2629540 0.924 rs2629541 chr10:126425866 G/A cg20435097 chr10:126320824 FAM53B -0.42 -6.16 -0.32 2.02e-9 Cocaine dependence; LIHC trans rs6934970 1.000 rs62413982 chr6:113102637 A/G cg09308777 chr6:169852575 NA 0.6 6.26 0.32 1.13e-9 Bipolar disorder (body mass index interaction); LIHC trans rs1814175 0.817 rs7929173 chr11:49944007 T/C cg15704280 chr7:45808275 SEPT13 -1.02 -23.4 -0.78 5.64e-73 Height; LIHC cis rs67311347 0.911 rs9849224 chr3:40392562 T/C cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.46e-9 Renal cell carcinoma; LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg00106254 chr7:1943704 MAD1L1 -0.47 -7.76 -0.39 9.66e-14 Bipolar disorder and schizophrenia; LIHC cis rs722599 0.715 rs2080086 chr14:75338408 G/A cg11812906 chr14:75593930 NEK9 -0.4 -6.28 -0.32 1.01e-9 IgG glycosylation; LIHC cis rs3768617 0.565 rs7542277 chr1:183063527 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.33 0.49 5.94e-22 Fuchs's corneal dystrophy; LIHC cis rs2645694 0.626 rs2703120 chr4:77822470 G/A cg03477792 chr4:77819574 ANKRD56 0.57 8.31 0.41 2.24e-15 Emphysema distribution in smoking; LIHC cis rs8141529 0.732 rs5997408 chr22:29207915 G/A cg02153584 chr22:29168773 CCDC117 0.58 9.42 0.45 7.06e-19 Lymphocyte counts; LIHC cis rs1494950 1.000 rs2604547 chr4:15089689 A/C cg12377275 chr4:15005593 CPEB2 -0.79 -7.1 -0.36 7.17e-12 Political ideology; LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg21747090 chr2:27597821 SNX17 -0.44 -6.55 -0.33 2.17e-10 Total body bone mineral density; LIHC cis rs716804 0.765 rs10743133 chr11:10307879 A/G cg01453529 chr11:10209919 SBF2 -0.29 -5.78 -0.3 1.64e-8 Neuroticism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03582286 chr4:71571171 RUFY3 0.41 6.17 0.32 1.92e-9 Lung function (FEV1/FVC); LIHC cis rs713477 0.967 rs6573028 chr14:55913397 C/T cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.45e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs13161895 1.000 rs13161895 chr5:179471201 C/T cg02702477 chr5:179499311 RNF130 0.8 11.17 0.52 6.67e-25 LDL cholesterol; LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg08219700 chr8:58056026 NA 0.53 7.04 0.36 1.06e-11 Developmental language disorder (linguistic errors); LIHC cis rs7829975 0.591 rs12677543 chr8:8644274 G/C cg06636001 chr8:8085503 FLJ10661 0.49 7.73 0.39 1.22e-13 Mood instability; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.48 11.15 0.52 7.52e-25 Calcium levels; LIHC cis rs4237845 0.537 rs1599931 chr12:58258850 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.6 8.26 0.41 3.21e-15 Intelligence (multi-trait analysis); LIHC cis rs921968 0.612 rs832810 chr2:219322430 T/C cg17980119 chr2:219472607 PLCD4 0.37 6.27 0.32 1.1e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg11062466 chr8:58055876 NA 0.5 7.32 0.37 1.82e-12 Developmental language disorder (linguistic errors); LIHC cis rs7937890 0.904 rs7484197 chr11:14283654 C/T cg02251663 chr11:14281053 SPON1 -0.47 -6.47 -0.33 3.42e-10 Mitochondrial DNA levels; LIHC cis rs288342 0.832 rs288311 chr2:183649700 C/T cg02625481 chr2:183667124 NA -0.29 -5.95 -0.31 6.48e-9 Recurrent major depressive disorder; LIHC cis rs12477438 0.765 rs13390672 chr2:99589829 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.45 -0.49 2.26e-22 Chronic sinus infection; LIHC cis rs4759375 0.915 rs11057273 chr12:123814466 T/C cg00376283 chr12:123451042 ABCB9 0.5 6.48 0.33 3.2e-10 HDL cholesterol; LIHC cis rs875971 0.861 rs801215 chr7:66011938 A/T cg11764359 chr7:65958608 NA -0.78 -13.61 -0.59 5.2e-34 Aortic root size; LIHC cis rs72634258 0.945 rs1883679 chr1:8100451 T/G cg00042356 chr1:8021962 PARK7 0.85 8.33 0.41 1.95e-15 Inflammatory bowel disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg06660842 chr3:93733689 ARL13B;STX19 0.31 6.11 0.31 2.65e-9 Hepatitis; LIHC cis rs7095944 0.614 rs10901816 chr10:126440395 G/A cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.87e-10 Asthma; LIHC cis rs875971 1.000 rs10215948 chr7:65747786 G/A cg11764359 chr7:65958608 NA -0.91 -16.72 -0.67 2.77e-46 Aortic root size; LIHC cis rs6933660 0.800 rs6930557 chr6:151755806 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.54 -8.16 -0.4 6.6e-15 Menarche (age at onset); LIHC trans rs7618501 0.815 rs3819325 chr3:49843723 T/C cg21659725 chr3:3221576 CRBN 0.94 17.44 0.69 3.65e-49 Intelligence (multi-trait analysis); LIHC cis rs117851058 0.590 rs2607412 chr19:41268243 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.47 -5.74 -0.3 2.04e-8 Post bronchodilator FEV1; LIHC cis rs262150 0.536 rs73167296 chr7:158783129 C/T cg13444538 chr7:158905317 VIPR2 -0.31 -5.8 -0.3 1.48e-8 Facial morphology (factor 20); LIHC cis rs747782 0.582 rs4752843 chr11:47531884 T/G cg20307385 chr11:47447363 PSMC3 -0.54 -6.16 -0.32 2.09e-9 Intraocular pressure; LIHC cis rs10791097 0.547 rs12365680 chr11:130749059 C/T cg22079354 chr11:130786696 SNX19 0.4 5.72 0.3 2.27e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1843834 0.838 rs6436506 chr2:225558242 T/C cg22455342 chr2:225449267 CUL3 0.44 6.33 0.32 7.55e-10 IgE levels in asthmatics (D.p. specific); LIHC cis rs9814567 1.000 rs6782563 chr3:134295959 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.26 0.32 1.13e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7216064 1.000 rs62084240 chr17:65859233 C/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.59e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs8038465 0.662 rs7497012 chr15:73968719 G/A cg15420318 chr15:73925796 NPTN 0.38 5.91 0.3 8.29e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs35306767 0.953 rs1539174 chr10:974870 C/G cg26597838 chr10:835615 NA 0.96 11.5 0.53 4.44e-26 Eosinophil percentage of granulocytes; LIHC cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.48 0.37 6.53e-13 Bipolar disorder; LIHC cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg05590025 chr7:65112418 INTS4L2 -0.58 -6.42 -0.33 4.57e-10 Diabetic kidney disease; LIHC cis rs17685 0.753 rs6465000 chr7:75787417 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.871 rs56048296 chr8:58163781 C/T cg02290350 chr8:58132656 NA 0.39 8.4 0.41 1.19e-15 Developmental language disorder (linguistic errors); LIHC cis rs7945705 0.714 rs2653570 chr11:8987823 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -7.08 -0.36 8.37e-12 Hemoglobin concentration; LIHC cis rs1577917 1.000 rs11759855 chr6:86610841 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.21 -0.36 3.63e-12 Response to antipsychotic treatment; LIHC cis rs6502050 0.805 rs62080003 chr17:80078957 C/T cg13198984 chr17:80129470 CCDC57 -0.33 -5.83 -0.3 1.26e-8 Life satisfaction; LIHC cis rs425277 0.606 rs424079 chr1:2071340 C/A cg24578937 chr1:2090814 PRKCZ -0.34 -6.09 -0.31 3.08e-9 Height; LIHC cis rs4713118 0.513 rs149955 chr6:28036225 G/C cg16479474 chr6:28041457 NA 0.39 6.36 0.33 6.35e-10 Parkinson's disease; LIHC cis rs11792861 0.962 rs3750454 chr9:111801325 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.61 -8.54 -0.42 4.58e-16 Menarche (age at onset); LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.28 0.55 5.92e-29 Prudent dietary pattern; LIHC cis rs2549003 1.000 rs2070728 chr5:131819977 C/T cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.25e-20 Asthma (sex interaction); LIHC cis rs881375 0.678 rs10760128 chr9:123696325 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 6.73 0.34 7.26e-11 Rheumatoid arthritis; LIHC cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg19318889 chr4:1322082 MAEA -0.46 -6.47 -0.33 3.33e-10 Obesity-related traits; LIHC cis rs12579753 0.879 rs35087297 chr12:82133398 C/T cg07988820 chr12:82153109 PPFIA2 -0.49 -6.16 -0.32 2.09e-9 Resting heart rate; LIHC cis rs7940866 0.903 rs10791112 chr11:130870215 A/C cg12179176 chr11:130786555 SNX19 -0.52 -7.48 -0.38 6.2800000000000005e-13 Schizophrenia; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg12371169 chr4:99182555 RAP1GDS1 -0.43 -6.21 -0.32 1.57e-9 Neuroblastoma; LIHC cis rs1997103 0.954 rs6593235 chr7:55410986 A/G cg17469321 chr7:55412551 NA 0.48 6.95 0.35 1.81e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10744422 0.858 rs4759389 chr12:123308615 A/G cg18912006 chr12:123335444 HIP1R -0.58 -7.03 -0.36 1.12e-11 Schizophrenia; LIHC cis rs7927771 0.524 rs10742814 chr11:47554337 G/A cg20307385 chr11:47447363 PSMC3 0.8 12.12 0.55 2.24e-28 Subjective well-being; LIHC cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg18357526 chr6:26021779 HIST1H4A -0.54 -7.13 -0.36 6.01e-12 Blood metabolite levels; LIHC cis rs16854884 0.683 rs920968 chr3:143770698 C/G cg06585982 chr3:143692056 C3orf58 0.45 6.37 0.33 6.17e-10 Economic and political preferences (feminism/equality); LIHC cis rs12586317 0.513 rs17102962 chr14:35478782 A/T cg05294307 chr14:35346193 BAZ1A -0.5 -7.42 -0.37 9.26e-13 Psoriasis; LIHC cis rs12701220 0.744 rs2030958 chr7:1076010 G/T cg26769984 chr7:1090371 C7orf50 0.64 8.11 0.4 9.3e-15 Bronchopulmonary dysplasia; LIHC cis rs4272321 1 rs4272321 chr7:157951835 A/G cg03377073 chr7:157980803 PTPRN2 0.34 6.95 0.35 1.81e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg00280220 chr17:61926910 NA 0.42 6.79 0.34 4.88e-11 Prudent dietary pattern; LIHC cis rs6489785 0.509 rs4767937 chr12:121223244 G/C cg02419362 chr12:121203948 SPPL3 0.33 5.76 0.3 1.91e-8 Longevity;Allergic disease (asthma, hay fever or eczema); LIHC cis rs6977660 1.000 rs10279525 chr7:19822305 C/T cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.34e-8 Thyroid stimulating hormone; LIHC cis rs7188697 0.922 rs6499962 chr16:58610750 A/C cg02549819 chr16:58548995 SETD6 0.49 7.64 0.38 2.25e-13 QT interval; LIHC cis rs6062509 0.630 rs6011058 chr20:62356627 C/T cg03999872 chr20:62272968 STMN3 0.41 6.08 0.31 3.29e-9 Prostate cancer; LIHC cis rs2303745 0.589 rs1864115 chr19:17393327 G/C cg04248312 chr19:17393744 ANKLE1 -0.74 -12.37 -0.56 2.77e-29 Systemic lupus erythematosus; LIHC cis rs16866061 0.515 rs13020268 chr2:225437923 C/T cg12698349 chr2:225449008 CUL3 0.9 20.85 0.75 6.94e-63 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs8078723 1.000 rs1042658 chr17:38173902 C/T cg17467752 chr17:38218738 THRA 0.75 13.68 0.59 2.85e-34 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2637266 1.000 rs2637264 chr10:78322794 A/C cg18941641 chr10:78392320 NA 0.29 6.12 0.31 2.55e-9 Pulmonary function; LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg02290350 chr8:58132656 NA 0.5 10.64 0.5 5.15e-23 Developmental language disorder (linguistic errors); LIHC cis rs1712517 0.740 rs11191643 chr10:105057561 C/G cg05636881 chr10:105038444 INA 0.5 7.86 0.39 5.01e-14 Migraine; LIHC cis rs8017423 0.967 rs12896540 chr14:90729392 T/C cg14092571 chr14:90743983 NA 0.44 6.9 0.35 2.46e-11 Mortality in heart failure; LIHC cis rs2070488 0.930 rs2370840 chr3:38529825 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 16.26 0.66 1.85e-44 Electrocardiographic conduction measures; LIHC trans rs208520 1.000 rs208537 chr6:66963544 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.69 -0.34 9.29e-11 Exhaled nitric oxide output; LIHC cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 8.27 0.41 2.94e-15 Platelet count; LIHC cis rs12887734 0.524 rs17791722 chr14:104286210 C/T cg24130564 chr14:104152367 KLC1 -0.44 -7.19 -0.36 4.01e-12 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs17685 0.753 rs2286830 chr7:75693963 C/T cg16489192 chr7:75678113 MDH2;STYXL1 0.39 6.43 0.33 4.22e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1843834 0.929 rs4674934 chr2:225516468 A/T cg22455342 chr2:225449267 CUL3 -0.41 -5.85 -0.3 1.13e-8 IgE levels in asthmatics (D.p. specific); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24504288 chr15:56996376 ZNF280D 0.28 6.21 0.32 1.52e-9 Cognitive function; LIHC trans rs6112176 0.679 rs6075446 chr20:18955126 A/G cg11266874 chr3:93699352 ARL13B -0.76 -6.12 -0.31 2.57e-9 Alcoholic chronic pancreatitis; LIHC cis rs919433 0.680 rs67580728 chr2:198431258 C/T cg10820045 chr2:198174542 NA 0.52 8.29 0.41 2.69e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2455799 0.573 rs2654648 chr3:15775425 T/C cg12698662 chr3:15914712 MIR563 -0.4 -7.49 -0.38 6e-13 Mean platelet volume; LIHC cis rs11758351 0.660 rs56398712 chr6:26213868 A/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.26 0.37 2.59e-12 Gout;Renal underexcretion gout; LIHC cis rs611744 0.967 rs2212704 chr8:109198415 C/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg09904177 chr6:26538194 HMGN4 0.55 10.78 0.5 1.65e-23 Intelligence (multi-trait analysis); LIHC cis rs6089829 0.962 rs2872543 chr20:61665017 G/A cg08564027 chr20:61660810 NA 0.39 7.55 0.38 4.07e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs1691799 0.899 rs903590 chr12:66745777 C/G cg16791601 chr12:66731901 HELB -0.54 -12.93 -0.57 2.05e-31 White blood cell count (basophil); LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg06420487 chr17:61919686 SMARCD2 0.45 6.13 0.31 2.45e-9 Height; LIHC cis rs6684514 1.000 rs12024813 chr1:156224529 C/A cg16558208 chr1:156270281 VHLL 0.51 9.26 0.45 2.31e-18 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs6500602 0.964 rs2896893 chr16:4478559 T/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.42 5.83 0.3 1.27e-8 Schizophrenia; LIHC cis rs11958404 0.932 rs72816541 chr5:157414686 G/A cg05962755 chr5:157440814 NA 0.91 10.22 0.48 1.37e-21 IgG glycosylation; LIHC cis rs1008375 0.835 rs9760627 chr4:17651508 C/T cg02297831 chr4:17616191 MED28 0.47 7.43 0.37 8.6e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2279817 0.863 rs3766311 chr1:17978186 G/C cg21791023 chr1:18019539 ARHGEF10L -0.66 -7.23 -0.36 3.23e-12 Neuroticism; LIHC cis rs2153535 0.542 rs9505465 chr6:8510846 C/T cg07606381 chr6:8435919 SLC35B3 0.8 11.76 0.54 4.85e-27 Motion sickness; LIHC cis rs2836950 0.545 rs8132424 chr21:40584412 A/T cg11890956 chr21:40555474 PSMG1 0.44 7.24 0.36 3.05e-12 Menarche (age at onset); LIHC cis rs12458462 0.851 rs2169249 chr18:77489649 G/A cg11879182 chr18:77439856 CTDP1 0.83 13.38 0.59 4.01e-33 Monocyte count; LIHC trans rs11098499 0.789 rs12498994 chr4:120250818 A/C cg25214090 chr10:38739885 LOC399744 0.51 8.29 0.41 2.61e-15 Corneal astigmatism; LIHC cis rs11148252 0.755 rs116860555 chr13:52936937 C/T cg00495681 chr13:53174319 NA -0.4 -6.45 -0.33 3.81e-10 Lewy body disease; LIHC cis rs11603020 0.950 rs11229063 chr11:57369730 G/A cg19752551 chr11:57585705 CTNND1 -0.46 -5.82 -0.3 1.35e-8 Blood protein levels; LIHC cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg25072359 chr17:41440525 NA 0.37 5.91 0.3 8.06e-9 Menopause (age at onset); LIHC cis rs17001868 0.568 rs12484697 chr22:40736472 A/G cg07138101 chr22:40742427 ADSL -0.57 -6.8 -0.35 4.57e-11 Mammographic density (dense area); LIHC cis rs9457247 1.000 rs364451 chr6:167384756 G/A cg23791538 chr6:167370224 RNASET2 -0.59 -9.41 -0.45 7.4e-19 Crohn's disease; LIHC cis rs55823223 0.564 rs4572466 chr17:73846314 A/C cg14829360 chr17:73884958 NA -0.51 -7.71 -0.38 1.37e-13 Psoriasis; LIHC cis rs2066819 1.000 rs2371494 chr12:56728000 G/A cg26714650 chr12:56694279 CS -1.25 -15.27 -0.64 1.6e-40 Psoriasis vulgaris; LIHC cis rs9649213 0.593 rs6955647 chr7:98004562 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.86 -0.3 1.06e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs7412746 0.658 rs12068264 chr1:150727329 C/T cg18016565 chr1:150552671 MCL1 0.56 10.71 0.5 2.81e-23 Melanoma; LIHC cis rs2380220 0.606 rs7747776 chr6:96005852 C/T cg04719120 chr6:96025338 MANEA 0.49 6.22 0.32 1.42e-9 Behavioural disinhibition (generation interaction); LIHC cis rs6732160 0.631 rs7557285 chr2:73442812 G/A cg24220031 chr2:73402428 NA -0.28 -6.01 -0.31 4.73e-9 Intelligence (multi-trait analysis); LIHC cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.74 7.41 0.37 9.71e-13 Platelet count; LIHC cis rs1559088 0.847 rs3760891 chr19:33599708 C/T cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9399137 0.507 rs61738647 chr6:135282735 T/C cg24558204 chr6:135376177 HBS1L 0.59 10.05 0.48 5.26e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs798554 0.679 rs1614791 chr7:2888057 G/T cg13628971 chr7:2884303 GNA12 0.62 10.27 0.49 9.5e-22 Height; LIHC cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7619427 0.822 rs62254362 chr3:44083403 C/A cg24966902 chr3:44043705 NA 0.45 5.92 0.3 7.82e-9 Schizophrenia; LIHC cis rs8180040 0.966 rs2062278 chr3:47416761 C/T cg27129171 chr3:47204927 SETD2 0.57 9.59 0.46 1.94e-19 Colorectal cancer; LIHC cis rs526231 0.853 rs2288786 chr5:102600754 C/T cg05225461 chr5:102596755 C5orf30 0.4 6.3 0.32 8.96e-10 Primary biliary cholangitis; LIHC cis rs3823572 0.542 rs62470446 chr7:133631002 C/T cg03336402 chr7:133662267 EXOC4 0.48 5.93 0.31 7.34e-9 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg12310025 chr6:25882481 NA -0.46 -5.84 -0.3 1.22e-8 Intelligence (multi-trait analysis); LIHC cis rs9921222 0.585 rs7195617 chr16:376781 A/G cg26944245 chr16:421049 TMEM8A;MRPL28 -0.51 -10.69 -0.5 3.44e-23 Bone mineral density (spine);Bone mineral density; LIHC cis rs3749237 0.595 rs4855877 chr3:49448527 T/C cg02487422 chr3:49467188 NICN1 0.37 5.83 0.3 1.29e-8 Resting heart rate; LIHC cis rs9399135 0.967 rs1041480 chr6:135373076 G/T cg22676075 chr6:135203613 NA 0.41 6.64 0.34 1.25e-10 Red blood cell count; LIHC cis rs61677309 1.000 rs12577820 chr11:118164233 C/T cg06090739 chr11:118230722 UBE4A 0.35 6.58 0.34 1.82e-10 Lung cancer in ever smokers; LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg18306943 chr3:40428807 ENTPD3 0.41 7.34 0.37 1.58e-12 Renal cell carcinoma; LIHC cis rs3762637 0.882 rs9818537 chr3:122086457 G/T cg24169773 chr3:122142474 KPNA1 -0.48 -9.3 -0.45 1.66e-18 LDL cholesterol levels; LIHC cis rs6570726 0.755 rs2092296 chr6:145893684 A/C cg05347473 chr6:146136440 FBXO30 0.39 6.14 0.31 2.35e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7980687 0.628 rs2851443 chr12:123694250 C/T cg00376283 chr12:123451042 ABCB9 0.68 10.27 0.49 9.37e-22 Height;Educational attainment;Head circumference (infant); LIHC cis rs57221529 0.766 rs72704799 chr5:551457 C/G cg09021430 chr5:549028 NA -0.45 -7.97 -0.4 2.36e-14 Lung disease severity in cystic fibrosis; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg09026481 chr5:74633022 HMGCR -0.5 -6.11 -0.31 2.74e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs7089973 0.604 rs11196941 chr10:116596258 A/G cg23260525 chr10:116636907 FAM160B1 0.35 7.04 0.36 1.03e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4927850 0.957 rs4927851 chr3:195751853 A/G cg12923728 chr3:195709715 SDHAP1 -0.72 -10.12 -0.48 3.25e-21 Pancreatic cancer; LIHC cis rs60871478 0.592 rs4275123 chr7:857352 A/G cg13798912 chr7:905769 UNC84A -0.54 -6.62 -0.34 1.37e-10 Cerebrospinal P-tau181p levels; LIHC cis rs1816752 0.870 rs73469543 chr13:24998970 T/C cg22771759 chr13:24902376 NA 0.31 6.29 0.32 9.98e-10 Obesity-related traits; LIHC cis rs875971 0.862 rs1875057 chr7:65731855 A/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC cis rs8062405 1.000 rs12325113 chr16:28848668 T/C cg07451762 chr16:28383216 NA 0.33 6.13 0.31 2.44e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3806843 0.735 rs2563333 chr5:140052271 A/G cg19875535 chr5:140030758 IK -0.37 -6.02 -0.31 4.43e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7927771 0.524 rs2290851 chr11:47753370 C/T cg20307385 chr11:47447363 PSMC3 -0.65 -9.85 -0.47 2.68e-20 Subjective well-being; LIHC cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg16606324 chr3:10149918 C3orf24 -0.49 -5.83 -0.3 1.29e-8 Alzheimer's disease; LIHC cis rs6502050 0.835 rs10163485 chr17:80110750 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs9467773 1.000 rs9467787 chr6:26556769 G/T cg09904177 chr6:26538194 HMGN4 0.65 13.83 0.6 7.52e-35 Intelligence (multi-trait analysis); LIHC cis rs644799 0.664 rs603625 chr11:95554283 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.76 13.01 0.58 1.07e-31 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3820068 0.705 rs4646083 chr1:15825564 G/A cg17385448 chr1:15911702 AGMAT 0.38 6.34 0.32 7.41e-10 Systolic blood pressure; LIHC cis rs9359856 0.564 rs72917989 chr6:90470385 A/T cg13799429 chr6:90582589 CASP8AP2 -0.66 -5.71 -0.3 2.45e-8 Bipolar disorder; LIHC trans rs2727020 0.521 rs937430 chr11:49542457 A/G cg03929089 chr4:120376271 NA 0.68 10.06 0.48 4.89e-21 Coronary artery disease; LIHC cis rs7107174 1.000 rs10793308 chr11:78086005 C/T cg02023728 chr11:77925099 USP35 0.4 7.37 0.37 1.33e-12 Testicular germ cell tumor; LIHC cis rs1801251 1.000 rs6738386 chr2:233602028 T/C cg25237894 chr2:233734115 C2orf82 0.57 11.03 0.51 2.04e-24 Coronary artery disease; LIHC cis rs8077889 0.956 rs61608877 chr17:41848713 A/C cg26893861 chr17:41843967 DUSP3 0.88 9.85 0.47 2.52e-20 Triglycerides; LIHC trans rs7193541 0.684 rs9923145 chr16:74686166 G/A cg23598604 chr1:99732472 LPPR4 -0.29 -6.21 -0.32 1.5e-9 Multiple myeloma; LIHC cis rs360798 0.532 rs360799 chr2:62953166 G/A cg17519650 chr2:63277830 OTX1 -0.54 -8.4 -0.41 1.19e-15 Coronary artery disease; LIHC cis rs2933343 0.672 rs1872545 chr3:128645039 G/C cg24203234 chr3:128598194 ACAD9 0.45 6.3 0.32 9.19e-10 IgG glycosylation; LIHC cis rs11098499 0.739 rs951570 chr4:120150467 T/C cg09307838 chr4:120376055 NA -0.5 -7.64 -0.38 2.17e-13 Corneal astigmatism; LIHC trans rs916888 0.821 rs199499 chr17:44865498 C/T cg07870213 chr5:140052090 DND1 0.94 7.93 0.39 3.08e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2236521 0.714 rs6062210 chr20:60890375 A/G cg09594475 chr20:60884601 LAMA5 0.56 9.44 0.45 6.07e-19 Pelvic organ prolapse; LIHC cis rs35110281 0.776 rs2838316 chr21:44990036 C/T cg04455712 chr21:45112962 RRP1B 0.47 7.96 0.4 2.53e-14 Mean corpuscular volume; LIHC cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg05896524 chr21:47604654 C21orf56 -0.49 -7.82 -0.39 6.58e-14 Testicular germ cell tumor; LIHC cis rs8060686 0.516 rs1975802 chr16:68285847 A/G cg09835421 chr16:68378352 PRMT7 -0.48 -5.9 -0.3 8.74e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs3020736 0.500 rs28791586 chr22:42500483 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC trans rs1814175 0.592 rs1794161 chr11:49898825 A/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg24101359 chr6:42928495 GNMT 0.51 6.67 0.34 1.02e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6840360 0.571 rs718801 chr4:152549247 C/T cg22705602 chr4:152727874 NA -0.33 -6.53 -0.33 2.42e-10 Intelligence (multi-trait analysis); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00593699 chr11:472782 PTDSS2 0.45 6.71 0.34 7.86e-11 Bilirubin levels; LIHC cis rs8067545 0.586 rs2703819 chr17:20121401 A/G cg13482628 chr17:19912719 NA -0.43 -7.06 -0.36 9.23e-12 Schizophrenia; LIHC cis rs7512552 0.803 rs11205385 chr1:150476516 G/A cg15654264 chr1:150340011 RPRD2 0.71 11.53 0.53 3.24e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs7618501 1.000 rs6775384 chr3:49853073 G/A cg21467203 chr3:49911342 NA -0.44 -7.59 -0.38 3.08e-13 Intelligence (multi-trait analysis); LIHC trans rs8073060 0.586 rs8077826 chr17:34001139 G/A cg19694781 chr19:47549865 TMEM160 -1.22 -12.48 -0.56 1.02e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs10423674 0.526 rs757317 chr19:18819984 C/T cg14292368 chr19:18793705 CRTC1 -0.42 -5.83 -0.3 1.27e-8 Menarche (age at onset); LIHC cis rs8017423 0.967 rs4904656 chr14:90721442 G/T cg04374321 chr14:90722782 PSMC1 0.77 15.19 0.63 3.32e-40 Mortality in heart failure; LIHC cis rs7927771 0.524 rs7107922 chr11:47669289 C/A cg20307385 chr11:47447363 PSMC3 0.77 11.76 0.54 4.89e-27 Subjective well-being; LIHC cis rs66569888 0.523 rs4522599 chr2:106926004 G/C cg16099169 chr2:106886729 NA 0.57 6.12 0.31 2.6e-9 Facial morphology (factor 23); LIHC cis rs10744422 0.858 rs2292136 chr12:123339344 A/G cg25930673 chr12:123319894 HIP1R -0.96 -12.76 -0.57 9.14e-31 Schizophrenia; LIHC cis rs17376456 0.542 rs2084916 chr5:93194961 A/T cg25358565 chr5:93447407 FAM172A -0.8 -7.7 -0.38 1.47e-13 Diabetic retinopathy; LIHC cis rs7927771 0.524 rs11039415 chr11:47845814 A/G cg20307385 chr11:47447363 PSMC3 0.75 11.26 0.52 3.03e-25 Subjective well-being; LIHC cis rs853679 0.517 rs9368551 chr6:28061792 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs7674212 0.539 rs7676041 chr4:104126421 T/A cg16532752 chr4:104119610 CENPE -0.46 -7.24 -0.36 3.03e-12 Type 2 diabetes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg09897639 chr1:178063342 RASAL2;LOC100302401 0.46 6.67 0.34 1.04e-10 Lung function (FEV1/FVC); LIHC trans rs10761482 0.600 rs1572843 chr10:62226980 C/T cg17314160 chr12:110399253 GIT2 -0.41 -6.11 -0.31 2.66e-9 Schizophrenia; LIHC cis rs28595532 0.702 rs56217716 chr4:119338490 T/G cg21605333 chr4:119757512 SEC24D 1.08 8.7 0.43 1.4e-16 Cannabis dependence symptom count; LIHC cis rs7508679 1.000 rs10401485 chr19:7222234 T/C cg09779027 chr19:7224513 INSR 0.29 6.55 0.33 2.12e-10 Hypothyroidism; LIHC cis rs2932538 0.702 rs7519368 chr1:113150644 T/A cg22162597 chr1:113214053 CAPZA1 0.66 8.86 0.43 4.52e-17 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07866137 chr8:67579786 VCPIP1 0.48 7.83 0.39 6e-14 Cognitive function; LIHC cis rs6815814 0.861 rs28690449 chr4:38789132 C/T cg06935464 chr4:38784597 TLR10 0.53 9.15 0.44 5.45e-18 Breast cancer; LIHC cis rs2933343 0.649 rs789214 chr3:128594995 A/G cg24203234 chr3:128598194 ACAD9 0.44 6.18 0.32 1.78e-9 IgG glycosylation; LIHC cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg03452623 chr4:187889614 NA -0.32 -8.21 -0.41 4.44e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.84 0.63 8.42e-39 Prudent dietary pattern; LIHC cis rs921968 0.521 rs56923478 chr2:219638539 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2280018 0.538 rs7404526 chr16:15129162 A/G cg27102117 chr16:15229624 NA 0.29 6.23 0.32 1.36e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs17376456 1.000 rs58734583 chr5:93532155 C/T cg25358565 chr5:93447407 FAM172A 1.06 9.65 0.46 1.25e-19 Diabetic retinopathy; LIHC cis rs2286503 0.839 rs2240726 chr7:22853135 C/T cg11367502 chr7:22862612 TOMM7 0.43 7.16 0.36 4.96e-12 Fibrinogen; LIHC cis rs7944735 0.508 rs111228939 chr11:47456067 T/C cg20307385 chr11:47447363 PSMC3 -0.54 -5.85 -0.3 1.16e-8 Intraocular pressure; LIHC cis rs6952808 0.929 rs2280546 chr7:1976863 G/A cg14004847 chr7:1930337 MAD1L1 -0.43 -6.19 -0.32 1.74e-9 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg11062466 chr8:58055876 NA 0.49 7.14 0.36 5.5e-12 Developmental language disorder (linguistic errors); LIHC cis rs6964587 1.000 rs2961020 chr7:91573308 G/A cg17063962 chr7:91808500 NA -1.03 -19.95 -0.73 2.89e-59 Breast cancer; LIHC cis rs3796352 1.000 rs13091844 chr3:53010271 C/T cg07884673 chr3:53033167 SFMBT1 0.91 6.6 0.34 1.58e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs919433 0.679 rs13000656 chr2:198522126 T/C cg00792783 chr2:198669748 PLCL1 -0.4 -5.89 -0.3 9.13e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs921968 0.541 rs3770213 chr2:219508372 A/T cg02176678 chr2:219576539 TTLL4 -0.58 -7.83 -0.39 6.1e-14 Mean corpuscular hemoglobin concentration; LIHC trans rs11098499 0.754 rs1511025 chr4:120240238 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs4803468 1.000 rs284658 chr19:41929988 G/A cg14132834 chr19:41945861 ATP5SL -0.46 -6.8 -0.35 4.7e-11 Height; LIHC cis rs6728642 0.519 rs4260285 chr2:97570081 A/G cg26665480 chr2:98280029 ACTR1B -0.6 -6.51 -0.33 2.75e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg04267008 chr7:1944627 MAD1L1 -0.64 -10.38 -0.49 3.99e-22 Bipolar disorder and schizophrenia; LIHC cis rs7707921 0.767 rs178931 chr5:81575601 T/A cg15871215 chr5:81402204 ATG10 0.68 8.17 0.4 6.13e-15 Breast cancer; LIHC cis rs11105298 0.891 rs10858869 chr12:89857611 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.54 -0.38 4.24e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg06969265 chr17:73775802 H3F3B 0.47 5.89 0.3 9.23e-9 Psoriasis; LIHC cis rs2576037 0.526 rs1539878 chr18:44523004 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 10.81 0.5 1.3e-23 Personality dimensions; LIHC cis rs1707322 0.752 rs4586014 chr1:46150443 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.27 0.37 2.45e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9388451 0.839 rs3799711 chr6:126075313 C/T cg05901451 chr6:126070800 HEY2 0.75 17.37 0.68 6.74e-49 Brugada syndrome; LIHC cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg04352962 chr1:209979756 IRF6 -0.37 -5.75 -0.3 2.01e-8 Cleft lip with or without cleft palate; LIHC cis rs11628318 0.660 rs8009475 chr14:103058608 A/G cg12046867 chr14:103022105 NA -0.5 -7.1 -0.36 7.46e-12 Platelet count; LIHC cis rs1801251 0.896 rs2197563 chr2:233687080 G/A cg25237894 chr2:233734115 C2orf82 -0.54 -10.31 -0.49 6.9e-22 Coronary artery disease; LIHC cis rs936229 0.768 rs11072509 chr15:75114374 C/G cg14664628 chr15:75095509 CSK -1.01 -21.18 -0.75 3.43e-64 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg24879335 chr3:133465180 TF 0.28 6.28 0.32 1e-9 Iron status biomarkers; LIHC cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg11764359 chr7:65958608 NA 0.59 6.2 0.32 1.65e-9 Diabetic kidney disease; LIHC cis rs6951245 0.554 rs2070118 chr7:1132505 G/A cg22907277 chr7:1156413 C7orf50 0.92 8.3 0.41 2.43e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12048904 0.619 rs10875346 chr1:101328083 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 11.4 0.52 9.42e-26 Multiple sclerosis; LIHC cis rs4319547 0.695 rs10846699 chr12:122853073 A/G cg05707623 chr12:122985044 ZCCHC8 0.55 7.24 0.36 2.96e-12 Body mass index; LIHC cis rs2070488 0.775 rs1073505 chr3:38566722 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.69 -11.34 -0.52 1.56e-25 Electrocardiographic conduction measures; LIHC cis rs7917772 0.582 rs10883738 chr10:104321721 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.5 7.88 0.39 4.45e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg16007711 chr8:22857750 RHOBTB2 -0.41 -6.16 -0.32 2.05e-9 Triglycerides; LIHC cis rs1355223 0.902 rs836467 chr11:34737432 G/A cg11058730 chr11:34937778 PDHX;APIP -0.47 -6.65 -0.34 1.13e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg04352962 chr1:209979756 IRF6 0.36 5.89 0.3 9.26e-9 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC cis rs546131 0.642 rs512013 chr11:34842225 C/T cg11058730 chr11:34937778 PDHX;APIP 0.65 9.31 0.45 1.64e-18 Lung disease severity in cystic fibrosis; LIHC cis rs370915 0.542 rs28440880 chr4:187793213 T/G cg12892747 chr4:187813459 NA -0.37 -5.74 -0.3 2.07e-8 Gout; LIHC cis rs7715806 0.509 rs34349 chr5:74944868 A/G cg02573091 chr5:74908125 NA -0.58 -6.83 -0.35 3.9e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg03806693 chr22:41940476 POLR3H 1.12 12.95 0.57 1.74e-31 Vitiligo; LIHC cis rs739401 0.572 rs739399 chr11:3016452 A/G cg20651018 chr11:3035856 CARS -0.34 -5.81 -0.3 1.45e-8 Longevity; LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg06420487 chr17:61919686 SMARCD2 0.43 5.89 0.3 9.12e-9 Height; LIHC cis rs943466 1.000 rs4711346 chr6:33730996 C/G cg25922239 chr6:33757077 LEMD2 -0.5 -6.3 -0.32 9.24e-10 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs12497850 0.931 rs9311434 chr3:48884147 T/C cg07636037 chr3:49044803 WDR6 0.91 16.39 0.66 5.92e-45 Parkinson's disease; LIHC cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg26939375 chr7:64535504 NA 0.47 7.19 0.36 4.13e-12 Calcium levels; LIHC cis rs950169 0.881 rs150965 chr15:85080527 T/G cg17507749 chr15:85114479 UBE2QP1 0.76 8.75 0.43 9.72e-17 Schizophrenia; LIHC cis rs72781680 0.898 rs72796171 chr2:23942667 G/C cg08917208 chr2:24149416 ATAD2B 0.85 7.76 0.39 1.01e-13 Lymphocyte counts; LIHC cis rs986417 1.000 rs1254332 chr14:60916587 T/C cg27398547 chr14:60952738 C14orf39 -0.81 -9.56 -0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs62005083 0.867 rs45569432 chr14:74666225 T/C cg05179529 chr14:74551516 LIN52;ALDH6A1 0.64 5.83 0.3 1.29e-8 Mean corpuscular volume; LIHC cis rs61677309 1.000 rs7480736 chr11:118172364 A/G cg06090739 chr11:118230722 UBE4A 0.34 6.41 0.33 4.92e-10 Lung cancer in ever smokers; LIHC trans rs1814175 0.519 rs10839291 chr11:49514321 G/A cg15704280 chr7:45808275 SEPT13 0.8 11.98 0.54 7.48e-28 Height; LIHC cis rs4638749 0.677 rs10454132 chr2:108828111 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.12 -0.31 2.51e-9 Blood pressure; LIHC cis rs2576037 0.583 rs9947131 chr18:44534769 G/T cg19077165 chr18:44547161 KATNAL2 -0.48 -7.23 -0.36 3.18e-12 Personality dimensions; LIHC cis rs1577917 1.000 rs34581302 chr6:86705948 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.66 -0.34 1.09e-10 Response to antipsychotic treatment; LIHC cis rs12477438 0.501 rs12995473 chr2:99764884 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.38 0.59 3.85e-33 Chronic sinus infection; LIHC cis rs6565180 0.632 rs8050812 chr16:30385837 C/T cg17640201 chr16:30407289 ZNF48 -0.75 -11.78 -0.54 4.12e-27 Tonsillectomy; LIHC cis rs968567 0.539 rs174555 chr11:61579760 T/C cg27386326 chr11:61587980 NA 0.69 14.45 0.62 2.72e-37 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.655 rs12702117 chr7:1148702 T/C cg26769984 chr7:1090371 C7orf50 0.48 5.88 0.3 9.58e-9 Bronchopulmonary dysplasia; LIHC trans rs2243480 1.000 rs34577383 chr7:65385726 C/T cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs2153535 0.601 rs9379224 chr6:8538413 A/G cg07606381 chr6:8435919 SLC35B3 0.77 10.88 0.51 7.41e-24 Motion sickness; LIHC cis rs8058578 0.945 rs8058961 chr16:30809063 G/A cg02466173 chr16:30829666 NA -0.41 -6.44 -0.33 4.15e-10 Multiple myeloma; LIHC cis rs908922 0.651 rs4240885 chr1:152529850 G/C cg20991723 chr1:152506922 NA 0.58 10.07 0.48 4.79e-21 Hair morphology; LIHC cis rs72627123 0.867 rs57731447 chr14:74487521 G/A cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.75 0.3 1.97e-8 Morning vs. evening chronotype; LIHC trans rs2096176 0.632 rs17813720 chr10:26318795 G/A cg01396774 chr2:218299024 DIRC3 -0.31 -6.05 -0.31 3.76e-9 Obesity-related traits; LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs12908161 0.920 rs35758837 chr15:85311382 C/T cg12863693 chr15:85201151 NMB 0.45 6.41 0.33 4.96e-10 Schizophrenia; LIHC cis rs6564851 0.545 rs4889285 chr16:81252258 C/T cg00908271 chr16:81254010 PKD1L2 -0.35 -7.42 -0.37 9.12e-13 Carotenoid and tocopherol levels; LIHC cis rs11958404 0.932 rs72816571 chr5:157429759 C/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.11e-27 IgG glycosylation; LIHC cis rs3091242 0.934 rs686631 chr1:25719599 A/T cg27572855 chr1:25598939 RHD 0.4 8.7 0.43 1.47e-16 Erythrocyte sedimentation rate; LIHC trans rs11098499 0.754 rs10006259 chr4:120242145 C/T cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg07677032 chr17:61819896 STRADA 0.43 6.13 0.31 2.43e-9 Prudent dietary pattern; LIHC cis rs763121 0.853 rs1569716 chr22:38998519 C/A cg21395723 chr22:39101663 GTPBP1 0.41 6.88 0.35 2.8e-11 Menopause (age at onset); LIHC cis rs9457247 0.967 rs1590257 chr6:167377782 G/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.85 -0.47 2.62e-20 Crohn's disease; LIHC cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg16434002 chr17:42200994 HDAC5 -0.51 -7.37 -0.37 1.29e-12 Total body bone mineral density; LIHC cis rs6762 0.719 rs28620453 chr11:836971 G/C cg15787769 chr11:842744 TSPAN4;POLR2L -0.61 -7.4 -0.37 1.04e-12 Mean platelet volume; LIHC cis rs12926788 0.640 rs12924246 chr16:24844629 A/G cg04756594 chr16:24857601 SLC5A11 0.58 8.78 0.43 8.21e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg22907277 chr7:1156413 C7orf50 0.81 6.96 0.35 1.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.98 20.42 0.74 3.78e-61 Height; LIHC cis rs6964587 1.000 rs13230588 chr7:91615427 C/A cg17063962 chr7:91808500 NA 1.01 19.32 0.72 9.73e-57 Breast cancer; LIHC cis rs9457247 0.967 rs433191 chr6:167409662 T/A cg12798992 chr6:167411361 FGFR1OP 0.62 10.3 0.49 7.73e-22 Crohn's disease; LIHC cis rs2050392 0.517 rs603072 chr10:30755778 C/T cg25182066 chr10:30743637 MAP3K8 0.67 10.9 0.51 6.13e-24 Inflammatory bowel disease; LIHC cis rs7095607 0.704 rs1900013 chr10:69953929 A/G cg18986048 chr10:69913749 MYPN 0.43 6.53 0.33 2.36e-10 Lung function (FVC); LIHC trans rs7448080 0.702 rs950392 chr5:123340716 A/G cg23779626 chr6:33864747 NA -0.59 -6.06 -0.31 3.62e-9 Alcohol dependence (age at onset); LIHC cis rs7769051 1.000 rs9493438 chr6:133098349 T/C cg07930552 chr6:133119739 C6orf192 0.72 6.92 0.35 2.27e-11 Type 2 diabetes nephropathy; LIHC cis rs11583043 1.000 rs35445887 chr1:101523639 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.59 7.93 0.39 3.14e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2439831 0.867 rs28415933 chr15:43635800 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.93 17.36 0.68 7.38e-49 Lung cancer in ever smokers; LIHC cis rs477692 1.000 rs485576 chr10:131425496 G/C cg19680672 chr10:131412579 MGMT -0.44 -6.73 -0.34 7.38e-11 Response to temozolomide; LIHC cis rs7615952 0.605 rs11708269 chr3:125332150 C/T cg05084668 chr3:125655381 ALG1L -0.59 -6.17 -0.32 1.98e-9 Blood pressure (smoking interaction); LIHC cis rs651907 0.557 rs11914318 chr3:101453858 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.45 -0.33 3.81e-10 Colorectal cancer; LIHC cis rs7945705 0.818 rs2742537 chr11:8908389 G/A cg12365402 chr11:9010492 NRIP3 -0.27 -7.06 -0.36 9.37e-12 Hemoglobin concentration; LIHC cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg08219700 chr8:58056026 NA -0.44 -5.83 -0.3 1.27e-8 Developmental language disorder (linguistic errors); LIHC cis rs2073300 1.000 rs34449811 chr20:23443771 T/C cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg20295408 chr7:1910781 MAD1L1 -0.49 -7.06 -0.36 9.55e-12 Bipolar disorder and schizophrenia; LIHC cis rs4665809 1.000 rs1470097 chr2:26312840 A/G cg27170947 chr2:26402098 FAM59B -0.61 -7.71 -0.38 1.39e-13 Gut microbiome composition (summer); LIHC cis rs7587476 0.601 rs13021937 chr2:215673937 C/T cg04004882 chr2:215674386 BARD1 -0.58 -8.33 -0.41 2.02e-15 Neuroblastoma; LIHC cis rs765787 0.530 rs2668751 chr15:45517293 T/C cg25801113 chr15:45476975 SHF 0.38 6.39 0.33 5.42e-10 Uric acid levels; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg00280220 chr17:61926910 NA 0.44 7.16 0.36 4.98e-12 Prudent dietary pattern; LIHC cis rs703842 1.000 rs8181644 chr12:58173466 A/G cg18357645 chr12:58087776 OS9 -0.44 -6.89 -0.35 2.65e-11 Multiple sclerosis; LIHC cis rs7474896 0.832 rs12570943 chr10:38022469 T/C cg25427524 chr10:38739819 LOC399744 -0.48 -5.97 -0.31 5.83e-9 Obesity (extreme); LIHC cis rs12142240 0.659 rs1984491 chr1:46858607 T/G cg00530320 chr1:46809349 NSUN4 0.53 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.1 11.21 0.52 4.58e-25 Platelet count; LIHC cis rs6582630 0.502 rs11610978 chr12:38356957 C/G cg26384229 chr12:38710491 ALG10B 0.56 7.92 0.39 3.44e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.57 0.46 2.16e-19 Height; LIHC cis rs970821 0.667 rs10956146 chr8:124749704 T/G cg00283535 chr8:124749564 ANXA13 -0.44 -7.93 -0.39 3.16e-14 Breast cancer; LIHC cis rs11792861 0.816 rs11790105 chr9:111731785 T/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.84 -0.35 3.69e-11 Menarche (age at onset); LIHC cis rs754466 0.580 rs1344966 chr10:79534527 T/C cg17075019 chr10:79541650 NA -0.8 -12.28 -0.55 5.73e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg27432699 chr2:27873401 GPN1 -0.5 -7.14 -0.36 5.59e-12 Total body bone mineral density; LIHC cis rs4819052 0.918 rs2330013 chr21:46658662 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 9.71 0.46 7.55e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9580312 0.706 rs9510016 chr13:22754512 G/A cg15352224 chr3:10157326 C3orf10 -0.45 -6.45 -0.33 3.85e-10 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs3784262 0.669 rs4646592 chr15:58302557 A/G cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.76 -0.3 1.9e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7020830 0.898 rs2047010 chr9:37077947 A/G cg14294708 chr9:37120828 ZCCHC7 1.11 23.84 0.79 1.03e-74 Schizophrenia; LIHC cis rs7772486 0.875 rs2207785 chr6:146332784 T/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.99 -0.31 5.36e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.48 0.56 1.06e-29 Prudent dietary pattern; LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 11.69 0.53 8.7e-27 Height; LIHC trans rs916888 0.821 rs199507 chr17:44858855 A/G cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4665809 1.000 rs6750681 chr2:26329677 C/T cg27170947 chr2:26402098 FAM59B -0.65 -8.28 -0.41 2.75e-15 Gut microbiome composition (summer); LIHC cis rs1866706 1.000 rs1866705 chr11:12867171 T/C cg25843174 chr11:12811716 TEAD1 -0.33 -6.92 -0.35 2.27e-11 Intelligence (multi-trait analysis); LIHC cis rs17102884 0.506 rs10873274 chr14:75407372 G/T cg08847533 chr14:75593920 NEK9 -0.63 -10.94 -0.51 4.46e-24 Neuroticism; LIHC cis rs7412746 0.571 rs12402939 chr1:150615094 A/C cg13175981 chr1:150552382 MCL1 -0.43 -5.9 -0.3 8.64e-9 Melanoma; LIHC cis rs7726839 0.555 rs4541696 chr5:581053 A/G cg09021430 chr5:549028 NA -0.34 -10.9 -0.51 5.97e-24 Obesity-related traits; LIHC cis rs9303280 0.517 rs12939566 chr17:38038390 A/T cg11212589 chr17:38028394 ZPBP2 0.35 7.09 0.36 7.92e-12 Self-reported allergy; LIHC cis rs2286885 1.000 rs1537989 chr9:129241824 C/T cg15282417 chr9:129245246 FAM125B 0.38 6.4 0.33 5.26e-10 Intraocular pressure; LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg02475777 chr4:1388615 CRIPAK 0.56 8.45 0.42 8.24e-16 Longevity; LIHC cis rs6988636 1.000 rs7002021 chr8:124185250 G/A cg15893493 chr8:124194847 FAM83A 0.89 8.3 0.41 2.48e-15 Urinary uromodulin levels; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg10150615 chr22:24372951 LOC391322 -0.46 -6.33 -0.32 7.75e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs722599 0.683 rs8008475 chr14:75291900 C/T cg08847533 chr14:75593920 NEK9 0.54 8.35 0.41 1.67e-15 IgG glycosylation; LIHC cis rs919433 0.617 rs700642 chr2:198600730 G/T cg00792783 chr2:198669748 PLCL1 -0.47 -7.01 -0.35 1.26e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6831352 0.819 rs13832 chr4:99993075 C/A cg12011299 chr4:100065546 ADH4 0.52 8.95 0.44 2.29e-17 Alcohol dependence; LIHC cis rs9911578 1.000 rs3744108 chr17:56585872 G/C cg12560992 chr17:57184187 TRIM37 -0.97 -17.33 -0.68 9.8e-49 Intelligence (multi-trait analysis); LIHC cis rs7000551 0.725 rs2248987 chr8:22399002 C/G cg12081754 chr8:22256438 SLC39A14 0.4 6.35 0.32 6.81e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs9911578 1.000 rs1472288 chr17:56910720 G/A cg12560992 chr17:57184187 TRIM37 0.96 17.37 0.68 6.51e-49 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.602 rs1831315 chr10:38473353 T/C cg25427524 chr10:38739819 LOC399744 -0.72 -14.09 -0.61 7.01e-36 Extrinsic epigenetic age acceleration; LIHC cis rs6753473 1.000 rs6753473 chr2:26526419 A/C cg26119090 chr2:26468346 HADHA;HADHB 0.86 6.1 0.31 2.87e-9 Non-small cell lung cancer; LIHC cis rs1494950 1.000 rs73797791 chr4:15051734 C/A cg12377275 chr4:15005593 CPEB2 -0.85 -7.78 -0.39 8.87e-14 Political ideology; LIHC cis rs11711311 1.000 rs62268168 chr3:113489447 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.94 -0.35 2e-11 IgG glycosylation; LIHC cis rs67311347 0.955 rs6773383 chr3:40377412 A/T cg00656387 chr3:40428638 ENTPD3 0.41 6.82 0.35 4.14e-11 Renal cell carcinoma; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg27484876 chr20:33872021 EIF6 -0.46 -6.65 -0.34 1.2e-10 Eotaxin levels; LIHC cis rs1008375 1.000 rs7659718 chr4:17638020 A/C cg16339924 chr4:17578868 LAP3 0.44 6.13 0.31 2.38e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6456156 0.586 rs1358882 chr6:167467101 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.71 -0.43 1.28e-16 Primary biliary cholangitis; LIHC cis rs6964587 1.000 rs13245393 chr7:91641928 A/G cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg23172400 chr8:95962367 TP53INP1 -0.43 -10.27 -0.49 9.53e-22 Type 2 diabetes; LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg11494091 chr17:61959527 GH2 0.36 5.81 0.3 1.4e-8 Height; LIHC cis rs35110281 0.627 rs1436291 chr21:44965485 T/C cg01579765 chr21:45077557 HSF2BP -0.33 -6.15 -0.32 2.2e-9 Mean corpuscular volume; LIHC cis rs10751667 0.666 rs10902249 chr11:958566 C/T cg06064525 chr11:970664 AP2A2 0.56 15.05 0.63 1.25e-39 Alzheimer's disease (late onset); LIHC cis rs875971 0.660 rs10263935 chr7:66096028 A/G cg18876405 chr7:65276391 NA 0.44 7.72 0.39 1.3e-13 Aortic root size; LIHC cis rs5769765 0.908 rs138866 chr22:50205903 A/G cg02269571 chr22:50332266 NA 0.66 8.9 0.43 3.44e-17 Schizophrenia; LIHC cis rs17539620 0.506 rs62432749 chr6:154839219 G/A cg20019720 chr6:154832845 CNKSR3 0.4 5.79 0.3 1.56e-8 Lipoprotein (a) levels; LIHC cis rs16828019 0.929 rs4131949 chr1:41738637 C/T cg03387723 chr1:41708464 SCMH1 -0.44 -7.13 -0.36 5.89e-12 Intelligence (multi-trait analysis); LIHC cis rs7572733 0.534 rs700672 chr2:198691455 G/A cg10820045 chr2:198174542 NA 0.46 6.9 0.35 2.59e-11 Dermatomyositis; LIHC cis rs4319547 0.737 rs10773176 chr12:122944713 A/G cg23029597 chr12:123009494 RSRC2 -0.44 -6.3 -0.32 8.94e-10 Body mass index; LIHC cis rs7592578 0.639 rs13417431 chr2:191293055 A/G cg27211696 chr2:191398769 TMEM194B -0.49 -6.45 -0.33 3.85e-10 Diastolic blood pressure; LIHC cis rs11711311 1.000 rs12736 chr3:113530211 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.87 -0.35 2.98e-11 IgG glycosylation; LIHC cis rs1801251 0.685 rs1515961 chr2:233623763 C/A cg08000102 chr2:233561755 GIGYF2 0.76 12.59 0.56 3.95e-30 Coronary artery disease; LIHC cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs7193541 0.684 rs4888265 chr16:74683737 T/C cg01733217 chr16:74700730 RFWD3 0.94 23.04 0.78 1.42e-71 Multiple myeloma; LIHC cis rs75908454 1.000 rs77129004 chr6:169822879 G/A cg19338460 chr6:170058176 WDR27 -0.86 -7.47 -0.37 6.6e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs807029 0.758 rs807025 chr10:102764821 C/T cg27255678 chr10:102756921 LZTS2 0.42 5.77 0.3 1.8e-8 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7534824 0.625 rs61780287 chr1:101382744 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 6.9 0.35 2.48e-11 Refractive astigmatism; LIHC trans rs8012283 0.656 rs10148502 chr14:51261957 A/G cg07338119 chr7:157211683 NA 0.66 6.09 0.31 3.02e-9 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg03806693 chr22:41940476 POLR3H 1.07 12.82 0.57 5.57e-31 Vitiligo; LIHC cis rs2153535 0.580 rs6421948 chr6:8531020 T/C cg07606381 chr6:8435919 SLC35B3 0.78 11.34 0.52 1.64e-25 Motion sickness; LIHC cis rs7131987 0.650 rs10843377 chr12:29437053 C/G cg12903224 chr12:29470962 FAR2 0.41 6.37 0.33 6.13e-10 QT interval; LIHC cis rs7940866 0.903 rs11222411 chr11:130838682 A/G cg12179176 chr11:130786555 SNX19 0.52 7.69 0.38 1.63e-13 Schizophrenia; LIHC cis rs7923837 0.651 rs11187107 chr10:94391697 G/A cg25506282 chr10:94462361 NA 0.34 5.76 0.3 1.85e-8 Body mass index;Multiple sclerosis; LIHC trans rs6598955 0.671 rs11247896 chr1:26600483 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs9902453 0.838 rs9646436 chr17:28209059 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 11.04 0.51 1.9e-24 Coffee consumption (cups per day); LIHC cis rs7618501 1.000 rs695238 chr3:49869158 A/C cg24110177 chr3:50126178 RBM5 -0.45 -7.05 -0.36 1.01e-11 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.566 rs9358902 chr6:26058570 C/G cg17691542 chr6:26056736 HIST1H1C 0.41 5.88 0.3 1e-8 Height; LIHC cis rs903552 0.932 rs11858490 chr15:102007443 G/T cg19295451 chr15:102010161 PCSK6 0.49 6.98 0.35 1.58e-11 Diabetic kidney disease; LIHC cis rs9768139 0.611 rs12698211 chr7:158119623 G/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.97 -0.31 6.01e-9 Calcium levels; LIHC cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg12463550 chr7:65579703 CRCP -0.64 -7.18 -0.36 4.31e-12 Diabetic kidney disease; LIHC trans rs9914544 0.689 rs8073236 chr17:18787182 C/G cg21372672 chr17:16614065 CCDC144A -0.33 -7.86 -0.39 4.93e-14 Educational attainment (years of education); LIHC cis rs7914558 0.966 rs56946876 chr10:104653545 T/C cg15744005 chr10:104629667 AS3MT -0.41 -9.29 -0.45 1.79e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9929218 0.861 rs3114409 chr16:68732049 A/C cg01231543 chr16:68741748 NA 0.4 6.09 0.31 3.08e-9 Colorectal cancer; LIHC cis rs5769707 0.681 rs739236 chr22:50041602 A/G cg01652190 chr22:50026171 C22orf34 -0.35 -7.74 -0.39 1.1e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1707322 0.721 rs7519900 chr1:46234947 C/T cg06784218 chr1:46089804 CCDC17 0.42 7.57 0.38 3.42e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9486719 0.948 rs11153059 chr6:97014537 T/A cg06623918 chr6:96969491 KIAA0776 -0.7 -7.21 -0.36 3.53e-12 Migraine;Coronary artery disease; LIHC cis rs7818382 0.967 rs7812465 chr8:96050557 C/T cg23172400 chr8:95962367 TP53INP1 0.3 6.81 0.35 4.41e-11 Alzheimer's disease (late onset); LIHC cis rs10857712 0.904 rs7083614 chr10:135226236 G/A cg01444801 chr10:135216882 MTG1 -0.64 -9.51 -0.46 3.63e-19 Systemic lupus erythematosus; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg06873352 chr17:61820015 STRADA 0.73 13.44 0.59 2.27e-33 Prudent dietary pattern; LIHC cis rs9660180 0.620 rs34298494 chr1:1663402 A/C cg27541892 chr1:1571801 CDK11B -0.6 -8.8 -0.43 6.86e-17 Body mass index; LIHC cis rs2239547 0.603 rs6805298 chr3:53096552 A/G cg11645453 chr3:52864694 ITIH4 -0.28 -7.21 -0.36 3.61e-12 Schizophrenia; LIHC cis rs4819052 0.851 rs2255766 chr21:46683777 C/T cg22633049 chr21:46681294 NA -0.37 -6.3 -0.32 9.26e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6088813 1.000 rs6088813 chr20:33975181 C/A cg14752227 chr20:34000481 UQCC -0.41 -5.83 -0.3 1.25e-8 Height; LIHC trans rs3812049 0.737 rs1993878 chr5:127476971 C/A cg16011800 chr17:1958478 HIC1 -0.53 -7.49 -0.38 6.1e-13 Lymphocyte counts;Red cell distribution width; LIHC cis rs9790314 0.838 rs4414866 chr3:160928709 C/T cg03342759 chr3:160939853 NMD3 -0.74 -9.18 -0.44 4.34e-18 Morning vs. evening chronotype; LIHC cis rs62064224 0.560 rs12162135 chr17:30805795 A/C cg25833597 chr17:30823145 MYO1D 0.36 6.03 0.31 4.18e-9 Schizophrenia; LIHC cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg06481639 chr22:41940642 POLR3H -0.74 -7.48 -0.37 6.46e-13 Vitiligo; LIHC cis rs651907 0.513 rs34963630 chr3:101504817 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.42 -5.84 -0.3 1.23e-8 Colorectal cancer; LIHC cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg24642844 chr7:1081250 C7orf50 -0.87 -8.69 -0.43 1.54e-16 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4900538 0.855 rs60215817 chr14:102873886 A/G cg18135206 chr14:102964638 TECPR2 -0.71 -10.95 -0.51 3.86e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs34779708 0.931 rs4934710 chr10:35350416 T/C cg03585969 chr10:35415529 CREM 0.86 12.99 0.57 1.26e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.48 -6.79 -0.34 5.01e-11 Lymphocyte counts; LIHC cis rs6840360 1.000 rs749982 chr4:152601353 A/G cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.42e-10 Intelligence (multi-trait analysis); LIHC cis rs77861329 0.920 rs9846049 chr3:52120214 A/G cg08692210 chr3:52188851 WDR51A 0.85 8.42 0.41 1.05e-15 Macrophage inflammatory protein 1b levels; LIHC cis rs6964587 0.869 rs7812219 chr7:91545727 C/T cg17063962 chr7:91808500 NA -0.98 -18.25 -0.7 2.02e-52 Breast cancer; LIHC cis rs2204008 0.837 rs2892296 chr12:37969785 C/T cg26384229 chr12:38710491 ALG10B -0.48 -6.73 -0.34 7.29e-11 Bladder cancer; LIHC cis rs2901460 0.509 rs12470090 chr2:62094367 T/C cg02183531 chr2:62113199 CCT4 -0.4 -5.88 -0.3 1e-8 Mean corpuscular volume; LIHC cis rs8060686 0.621 rs35432211 chr16:68095449 T/C cg05110241 chr16:68378359 PRMT7 -0.6 -6.94 -0.35 2.02e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs6570726 1.000 rs404229 chr6:145868200 G/A cg23711669 chr6:146136114 FBXO30 0.53 9.21 0.45 3.29e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg06108461 chr20:60628389 TAF4 -1.03 -18.03 -0.7 1.5e-51 Body mass index; LIHC cis rs7674212 0.541 rs4699051 chr4:104114394 T/C cg16532752 chr4:104119610 CENPE -0.45 -7.01 -0.35 1.25e-11 Type 2 diabetes; LIHC cis rs651907 0.535 rs34063583 chr3:101509948 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs8180040 0.874 rs11130123 chr3:47285912 A/G cg16586182 chr3:47516702 SCAP -0.53 -9.5 -0.46 3.72e-19 Colorectal cancer; LIHC cis rs801193 0.569 rs11761542 chr7:66218196 G/A cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.34e-11 Aortic root size; LIHC cis rs6952808 0.693 rs10950413 chr7:1912988 A/G cg20295408 chr7:1910781 MAD1L1 -0.5 -7.26 -0.37 2.71e-12 Bipolar disorder and schizophrenia; LIHC cis rs986417 0.818 rs10144990 chr14:60927816 T/C cg27398547 chr14:60952738 C14orf39 0.77 8.77 0.43 8.38e-17 Gut microbiota (bacterial taxa); LIHC cis rs7188697 0.921 rs12445577 chr16:58587164 T/C cg02549819 chr16:58548995 SETD6 0.48 7.59 0.38 3.16e-13 QT interval; LIHC cis rs2072499 0.966 rs2853646 chr1:156189626 C/T cg25208724 chr1:156163844 SLC25A44 0.89 14.29 0.61 1.15e-36 Testicular germ cell tumor; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC trans rs11165623 0.792 rs12132069 chr1:96918809 A/C cg10631902 chr5:14652156 NA -0.35 -8.9 -0.43 3.4e-17 Hip circumference;Waist circumference; LIHC cis rs7903847 0.642 rs11189179 chr10:99143320 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12922317 0.964 rs8061496 chr16:12076752 A/G cg09319797 chr16:12061715 TNFRSF17 0.41 7.16 0.36 5.07e-12 Schizophrenia; LIHC cis rs1144333 0.655 rs946164 chr1:76383286 A/T cg22875332 chr1:76189707 ACADM 0.41 6.16 0.32 2.05e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs1816752 0.905 rs7571 chr13:25000617 C/G cg02811702 chr13:24901961 NA 0.24 6.01 0.31 4.84e-9 Obesity-related traits; LIHC cis rs1801251 0.963 rs283481 chr2:233648091 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.11 0.52 1.07e-24 Coronary artery disease; LIHC cis rs1799949 0.929 rs799905 chr17:41277187 G/C cg23758822 chr17:41437982 NA 0.95 17.96 0.7 2.95e-51 Menopause (age at onset); LIHC cis rs713477 1.000 rs2185036 chr14:55907710 A/G cg13175173 chr14:55914753 NA -0.35 -8.13 -0.4 7.79e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs870825 0.929 rs870822 chr4:185588200 C/T cg04058563 chr4:185651563 MLF1IP 0.7 6.17 0.32 1.96e-9 Blood protein levels; LIHC cis rs4808199 0.947 rs754255 chr19:19578890 T/C cg03709012 chr19:19516395 GATAD2A 1.08 19.4 0.72 4.5e-57 Nonalcoholic fatty liver disease; LIHC cis rs240764 0.621 rs6570930 chr6:101181258 C/A cg09795085 chr6:101329169 ASCC3 -0.45 -6.59 -0.34 1.66e-10 Neuroticism; LIHC trans rs35110281 0.782 rs6518309 chr21:45047992 C/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.47 6.13 0.31 2.42e-9 Mean corpuscular volume; LIHC cis rs860295 1.000 rs6427287 chr1:155723420 T/C cg02153340 chr1:155202674 NA -0.32 -5.91 -0.3 8.24e-9 Body mass index; LIHC cis rs9457247 0.624 rs17524252 chr6:167466978 T/G cg23791538 chr6:167370224 RNASET2 -0.51 -7.81 -0.39 6.86e-14 Crohn's disease; LIHC cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg06634786 chr22:41940651 POLR3H -0.81 -8.96 -0.44 2.09e-17 Vitiligo; LIHC cis rs7192750 0.586 rs11075908 chr16:71928850 C/T cg06353428 chr16:71660113 MARVELD3 -0.8 -9.13 -0.44 5.89e-18 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs4689592 0.503 rs3857180 chr4:7073899 T/G cg19539972 chr4:7069911 GRPEL1 -0.74 -10.25 -0.48 1.13e-21 Monocyte percentage of white cells; LIHC cis rs9788721 0.592 rs28564957 chr15:78906107 C/A cg06917634 chr15:78832804 PSMA4 -0.54 -7.61 -0.38 2.66e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; LIHC cis rs9393692 0.846 rs7771202 chr6:26279907 A/G cg05868516 chr6:26286170 HIST1H4H 0.41 6.25 0.32 1.21e-9 Educational attainment; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg21653586 chr11:10530636 NA 0.43 6.1 0.31 2.88e-9 Immature fraction of reticulocytes; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg08726195 chr7:77427851 PHTF2;TMEM60 -0.55 -6.18 -0.32 1.85e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs1448094 0.512 rs6539926 chr12:86244460 G/A cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs2832191 0.740 rs2832168 chr21:30463695 G/A cg08807101 chr21:30365312 RNF160 0.79 12.2 0.55 1.19e-28 Dental caries; LIHC cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg16497277 chr3:49208875 KLHDC8B -0.49 -5.89 -0.3 9.23e-9 Parkinson's disease; LIHC cis rs2380220 0.810 rs877096 chr6:95937046 A/G cg15832292 chr6:96025679 MANEA -0.6 -6.73 -0.34 7.25e-11 Behavioural disinhibition (generation interaction); LIHC cis rs860295 0.650 rs28662267 chr1:155680449 T/C cg02153340 chr1:155202674 NA -0.35 -6.42 -0.33 4.57e-10 Body mass index; LIHC cis rs2251381 0.750 rs2776250 chr21:30528094 T/G cg24692254 chr21:30365293 RNF160 0.71 10.3 0.49 7.86e-22 Selective IgA deficiency; LIHC cis rs9311474 0.607 rs4475032 chr3:52560021 C/T cg10802521 chr3:52805072 NEK4 -0.39 -6.44 -0.33 4.05e-10 Electroencephalogram traits; LIHC cis rs11711311 0.955 rs12634241 chr3:113397685 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.33 5.75 0.3 1.99e-8 IgG glycosylation; LIHC cis rs9733 0.596 rs11582840 chr1:150688487 A/G cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg00149659 chr3:10157352 C3orf10 0.69 6.99 0.35 1.49e-11 Alzheimer's disease; LIHC cis rs5769765 0.740 rs2103932 chr22:50272515 A/G cg26441486 chr22:50317300 CRELD2 -0.33 -5.91 -0.3 8.34e-9 Schizophrenia; LIHC cis rs7312774 0.618 rs7975954 chr12:107345750 C/T cg16260113 chr12:107380972 MTERFD3 0.85 11.13 0.52 9.19e-25 Severe influenza A (H1N1) infection; LIHC cis rs5769707 0.846 rs5770610 chr22:50036897 A/C cg07959070 chr22:50026188 C22orf34 -0.33 -8.5 -0.42 5.96e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9318086 0.935 rs9553083 chr13:24441525 C/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.54 -10.88 -0.51 7.04e-24 Myopia (pathological); LIHC cis rs2153535 0.580 rs2184582 chr6:8447793 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC cis rs950169 0.580 rs11635597 chr15:85165699 C/T cg03959625 chr15:84868606 LOC388152 0.44 6.12 0.31 2.64e-9 Schizophrenia; LIHC cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg12463550 chr7:65579703 CRCP 0.68 7.14 0.36 5.69e-12 Diabetic kidney disease; LIHC cis rs116095464 0.558 rs1812843 chr5:267658 A/G cg22857025 chr5:266934 NA -1.52 -18.96 -0.72 2.61e-55 Breast cancer; LIHC cis rs11758351 1.000 rs80313145 chr6:26194965 T/A cg16070018 chr6:26224392 HIST1H3E 0.53 6.31 0.32 8.62e-10 Gout;Renal underexcretion gout; LIHC cis rs763121 0.819 rs5757161 chr22:38990662 G/A cg21395723 chr22:39101663 GTPBP1 0.37 6.28 0.32 1.06e-9 Menopause (age at onset); LIHC cis rs4700695 0.764 rs10066817 chr5:65319853 A/G cg21114390 chr5:65439923 SFRS12 0.45 5.87 0.3 1.05e-8 Facial morphology (factor 19); LIHC cis rs12594515 1.000 rs35182335 chr15:45995184 C/G cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs8141529 0.588 rs10222249 chr22:29257147 A/G cg15103426 chr22:29168792 CCDC117 0.51 7.84 0.39 5.71e-14 Lymphocyte counts; LIHC cis rs921968 0.541 rs488767 chr2:219466860 G/T cg02176678 chr2:219576539 TTLL4 0.53 7.3 0.37 2.02e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs72949976 0.898 rs6732233 chr2:214022834 C/T cg08319019 chr2:214017104 IKZF2 -0.59 -6.33 -0.32 7.7e-10 Lung cancer;Squamous cell lung carcinoma; LIHC cis rs7582180 0.629 rs12989897 chr2:100940998 A/G cg14675211 chr2:100938903 LONRF2 0.53 8.29 0.41 2.55e-15 Intelligence (multi-trait analysis); LIHC cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg12310025 chr6:25882481 NA -0.6 -8.51 -0.42 5.36e-16 Blood metabolite levels; LIHC trans rs561341 1.000 rs2344312 chr17:30243583 G/T cg20587970 chr11:113659929 NA -0.61 -7.37 -0.37 1.3e-12 Hip circumference adjusted for BMI; LIHC cis rs208520 0.690 rs1233103 chr6:66855943 T/G cg07460842 chr6:66804631 NA -0.79 -8.85 -0.43 4.67e-17 Exhaled nitric oxide output; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25983288 chr5:137681122 FAM53C 0.43 6.52 0.33 2.6e-10 Immature fraction of reticulocytes; LIHC cis rs780096 0.546 rs35073769 chr2:27731376 C/T cg22903471 chr2:27725779 GCKR -0.53 -9.1 -0.44 7.85e-18 Total body bone mineral density; LIHC cis rs644799 1.000 rs543530 chr11:95545170 A/G cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11676855 1.000 rs729866 chr2:235899359 G/A cg14917874 chr2:235941519 SH3BP4 0.53 7.1 0.36 7.34e-12 Dialysis-related mortality; LIHC cis rs9733 0.596 rs12086472 chr1:150697710 G/A cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC trans rs116095464 0.558 rs6879656 chr5:264428 T/C cg00938859 chr5:1591904 SDHAP3 0.58 6.65 0.34 1.13e-10 Breast cancer; LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs2073499 0.935 rs28365992 chr3:50340996 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.67 7.58 0.38 3.32e-13 Schizophrenia; LIHC cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.55 0.56 5.46e-30 Alzheimer's disease; LIHC cis rs3749237 0.595 rs4855859 chr3:49526300 C/T cg02487422 chr3:49467188 NICN1 0.41 6.32 0.32 8.18e-10 Resting heart rate; LIHC cis rs7843479 0.562 rs11774629 chr8:21859315 C/T cg17168535 chr8:21777572 XPO7 0.58 10.29 0.49 8.01e-22 Mean corpuscular volume; LIHC trans rs11098499 0.754 rs2036856 chr4:120249288 G/A cg25214090 chr10:38739885 LOC399744 0.51 8.27 0.41 3.06e-15 Corneal astigmatism; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26853048 chr5:132387620 HSPA4 -0.4 -6.06 -0.31 3.63e-9 Systolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05635121 chr17:7154132 C17orf81;DULLARD 0.49 7.45 0.37 7.86e-13 Cognitive function; LIHC cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.58 -0.34 1.76e-10 Gut microbiome composition (summer); LIHC cis rs1005277 0.579 rs2472182 chr10:38388865 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs769267 0.965 rs10419245 chr19:19383755 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.61 9.4 0.45 8.28e-19 Tonsillectomy; LIHC cis rs7044106 0.762 rs7357638 chr9:123389204 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 10.97 0.51 3.3e-24 Hip circumference adjusted for BMI; LIHC cis rs56176327 0.532 rs9849038 chr3:49771990 A/G cg03060546 chr3:49711283 APEH 0.58 6.72 0.34 7.66e-11 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs9393692 0.905 rs9379838 chr6:26277133 C/T cg00631329 chr6:26305371 NA -0.43 -7.25 -0.36 2.88e-12 Educational attainment; LIHC cis rs2180341 0.960 rs7766802 chr6:127709871 T/G cg27446573 chr6:127587934 RNF146 1.01 15.91 0.65 4.71e-43 Breast cancer; LIHC cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs2153535 0.563 rs1796687 chr6:8536118 C/G cg23788917 chr6:8435910 SLC35B3 0.59 8.53 0.42 4.92e-16 Motion sickness; LIHC cis rs4853036 0.903 rs13021969 chr2:70117602 T/C cg02498382 chr2:70120550 SNRNP27 -0.42 -6.82 -0.35 4.21e-11 Colorectal or endometrial cancer; LIHC trans rs911555 0.755 rs17841064 chr14:103900609 A/G cg17675199 chr6:35436792 RPL10A 0.46 9.69 0.46 8.54e-20 Intelligence (multi-trait analysis); LIHC cis rs9649213 0.586 rs11768599 chr7:97974555 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.58 -10.28 -0.49 8.9e-22 Prostate cancer (SNP x SNP interaction); LIHC trans rs9733 0.596 rs7412396 chr1:150666797 C/T cg06135574 chr16:1550622 TELO2 0.38 6.17 0.32 1.96e-9 Tonsillectomy; LIHC cis rs8103278 1.000 rs11671524 chr19:46327166 G/A cg14061069 chr19:46274453 DMPK -0.55 -8.44 -0.42 8.96e-16 Coronary artery disease; LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg14004847 chr7:1930337 MAD1L1 -0.47 -6.91 -0.35 2.4e-11 Bipolar disorder and schizophrenia; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.6 -0.34 1.55e-10 Total body bone mineral density; LIHC cis rs6912958 0.781 rs7750207 chr6:88303967 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.63 -0.38 2.35e-13 Monocyte percentage of white cells; LIHC cis rs778371 0.723 rs13001052 chr2:233683984 C/T cg08000102 chr2:233561755 GIGYF2 -0.76 -9.25 -0.45 2.45e-18 Schizophrenia; LIHC cis rs826838 0.900 rs1403523 chr12:39130570 T/A cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs7903847 0.642 rs12258560 chr10:99137048 T/C cg06359132 chr10:99160096 RRP12 -0.42 -6.54 -0.33 2.24e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12497850 0.797 rs61583136 chr3:49189195 C/T cg16497277 chr3:49208875 KLHDC8B -0.48 -5.86 -0.3 1.09e-8 Parkinson's disease; LIHC cis rs10849605 0.867 rs10849602 chr12:1062479 A/G cg22937753 chr12:1022477 RAD52 -0.37 -7.02 -0.36 1.18e-11 Lung cancer; LIHC cis rs2230307 0.536 rs7518943 chr1:100463422 G/T cg24955406 chr1:100503596 HIAT1 0.6 6.28 0.32 1.02e-9 Carotid intima media thickness; LIHC cis rs6089829 0.962 rs6122347 chr20:61661866 C/T cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs875971 0.522 rs1968127 chr7:66056803 C/T cg11764359 chr7:65958608 NA -0.72 -11.01 -0.51 2.56e-24 Aortic root size; LIHC cis rs1059312 0.545 rs7312683 chr12:129280105 T/C cg09035930 chr12:129282057 SLC15A4 0.51 7.9 0.39 3.78e-14 Systemic lupus erythematosus; LIHC cis rs7412746 0.611 rs72704679 chr1:150897477 C/T cg15448220 chr1:150897856 SETDB1 0.39 6.25 0.32 1.22e-9 Melanoma; LIHC cis rs1008375 0.932 rs4698626 chr4:17605821 G/C cg16339924 chr4:17578868 LAP3 0.41 5.73 0.3 2.25e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs916888 0.687 rs199456 chr17:44797919 C/T cg07870213 chr5:140052090 DND1 1.04 10.68 0.5 3.72e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs66887589 0.777 rs1814815 chr4:120258091 C/T cg25214090 chr10:38739885 LOC399744 0.4 6.73 0.34 6.99e-11 Diastolic blood pressure; LIHC cis rs317689 0.600 rs478863 chr12:69639207 G/A cg14784868 chr12:69753453 YEATS4 0.51 6.94 0.35 2e-11 Response to diuretic therapy; LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg06558623 chr16:89946397 TCF25 1.0 15.61 0.65 7.51e-42 Skin colour saturation; LIHC cis rs6545883 0.860 rs6749226 chr2:61509783 G/A cg15711740 chr2:61764176 XPO1 0.41 5.73 0.3 2.24e-8 Tuberculosis; LIHC cis rs12497850 1.000 rs4858831 chr3:48735558 C/T cg07636037 chr3:49044803 WDR6 0.79 13.72 0.6 2.01e-34 Parkinson's disease; LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.78e-9 Menopause (age at onset); LIHC cis rs17685 0.587 rs1623759 chr7:75724679 A/T cg04610667 chr7:75704037 NA -0.33 -5.94 -0.31 6.93e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs240764 0.817 rs12193960 chr6:101150326 C/T cg09795085 chr6:101329169 ASCC3 -0.52 -7.14 -0.36 5.5e-12 Neuroticism; LIHC cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg16262614 chr3:133464971 TF 0.28 6.12 0.31 2.6e-9 Iron status biomarkers; LIHC cis rs367615 0.918 rs4576198 chr5:108867350 T/G cg17395555 chr5:108820864 NA 0.35 7.14 0.36 5.67e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs11758351 1.000 rs2143346 chr6:26198449 C/G cg16070018 chr6:26224392 HIST1H3E -0.54 -6.58 -0.34 1.76e-10 Gout;Renal underexcretion gout; LIHC cis rs904251 0.522 rs882322 chr6:37484103 A/G cg01843034 chr6:37503916 NA -0.46 -7.97 -0.4 2.41e-14 Cognitive performance; LIHC cis rs7772486 0.754 rs864148 chr6:145976675 T/C cg13319975 chr6:146136371 FBXO30 0.39 6.47 0.33 3.33e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg13078911 chr2:44393479 NA 0.36 6.13 0.31 2.46e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs17685 0.753 rs9691174 chr7:75790405 T/C cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.57e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg09455208 chr3:40491958 NA 0.41 8.25 0.41 3.45e-15 Renal cell carcinoma; LIHC cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg18404041 chr3:52824283 ITIH1 -0.59 -9.34 -0.45 1.27e-18 Bipolar disorder; LIHC cis rs67311347 0.824 rs59922539 chr3:40337110 G/A cg00656387 chr3:40428638 ENTPD3 0.38 5.94 0.31 6.88e-9 Renal cell carcinoma; LIHC trans rs783540 0.846 rs783534 chr15:83250243 C/T cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.19 -0.32 1.71e-9 Schizophrenia; LIHC cis rs763512 0.504 rs1051838 chr17:35870833 G/A cg16670864 chr17:35848621 DUSP14 0.35 5.75 0.3 1.96e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs3782089 1.000 rs11600543 chr11:65298939 G/A cg00206168 chr11:65308501 LTBP3 1.09 7.68 0.38 1.71e-13 Height; LIHC cis rs1538970 1.000 rs11211101 chr1:45849311 C/G cg05343316 chr1:45956843 TESK2 0.61 9.17 0.44 4.39e-18 Platelet count; LIHC cis rs904251 0.861 rs2776877 chr6:37487135 G/A cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.39e-12 Cognitive performance; LIHC cis rs3814113 0.546 rs7868157 chr9:16851977 C/A cg13173848 chr9:16870893 BNC2 0.64 7.07 0.36 8.97e-12 Epithelial ovarian cancer;Ovarian cancer in BRCA1 mutation carriers;Ovarian cancer; LIHC cis rs56104184 0.775 rs17272707 chr19:49404535 T/G cg21252483 chr19:49399788 TULP2 -1.06 -12.19 -0.55 1.21e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.13 12.58 0.56 4.25e-30 Platelet count; LIHC cis rs2243480 0.615 rs34363376 chr7:65939536 T/C cg18252515 chr7:66147081 NA -1.3 -16.66 -0.67 4.63e-46 Diabetic kidney disease; LIHC cis rs4474465 0.688 rs4944210 chr11:78282878 C/T cg02023728 chr11:77925099 USP35 -0.34 -6.01 -0.31 4.72e-9 Alzheimer's disease (survival time); LIHC cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.84 0.3 1.22e-8 Aortic root size; LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg04267008 chr7:1944627 MAD1L1 -0.6 -9.21 -0.45 3.26e-18 Bipolar disorder and schizophrenia; LIHC cis rs7408868 0.908 rs10416777 chr19:15276923 C/T cg14696996 chr19:15285081 NOTCH3 0.53 7.1 0.36 7.41e-12 Pulse pressure; LIHC cis rs2274273 0.712 rs7144652 chr14:55537718 G/A cg01864836 chr14:55583639 NA -0.38 -6.48 -0.33 3.18e-10 Protein biomarker; LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg11060661 chr22:24314208 DDT;DDTL -0.56 -8.99 -0.44 1.69e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9309473 0.898 rs6546851 chr2:73833283 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.92 -0.35 2.17e-11 Metabolite levels; LIHC cis rs11252926 0.545 rs11252693 chr10:532139 A/G cg09445902 chr10:555545 DIP2C -0.38 -6.15 -0.32 2.11e-9 Psychosis in Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07830086 chr19:18107778 KCNN1 0.47 6.13 0.31 2.41e-9 Lung function (FEV1/FVC); LIHC cis rs4555082 0.957 rs2816628 chr14:105736134 T/G cg06808227 chr14:105710500 BRF1 -0.61 -8.72 -0.43 1.2e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs7395581 0.918 rs12575456 chr11:47326073 G/A cg26139080 chr11:47293733 MADD -0.5 -8.44 -0.42 8.85e-16 HDL cholesterol; LIHC cis rs4906332 1.000 rs3783400 chr14:103967045 G/A cg19000871 chr14:103996768 TRMT61A -0.46 -7.75 -0.39 1.04e-13 Coronary artery disease; LIHC cis rs6754311 0.731 rs748841 chr2:136558157 C/T cg17750252 chr2:136567154 LCT 0.34 6.24 0.32 1.27e-9 Mosquito bite size; LIHC cis rs2153535 0.580 rs7341201 chr6:8470270 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs8067545 0.586 rs3850779 chr17:20171872 C/T cg13482628 chr17:19912719 NA -0.42 -6.79 -0.34 5.01e-11 Schizophrenia; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg00280220 chr17:61926910 NA 0.41 6.5 0.33 2.79e-10 Prudent dietary pattern; LIHC cis rs11098499 0.866 rs13105020 chr4:120285688 G/T cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs7617773 0.817 rs34728236 chr3:48259108 A/G cg11946769 chr3:48343235 NME6 0.89 10.97 0.51 3.51e-24 Coronary artery disease; LIHC cis rs1577917 1.000 rs12208493 chr6:86662267 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.83 -0.35 3.94e-11 Response to antipsychotic treatment; LIHC trans rs7246657 0.943 rs34603719 chr19:37794528 T/G cg10208301 chr11:6592745 DNHD1 0.46 6.08 0.31 3.28e-9 Coronary artery calcification; LIHC cis rs4728302 0.838 rs6974143 chr7:133603550 G/A cg10665199 chr7:133106180 EXOC4 0.39 6.82 0.35 4.1e-11 Intelligence;Intelligence (multi-trait analysis); LIHC trans rs7246657 0.943 rs1015848 chr19:37945274 A/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs9549367 0.789 rs9577220 chr13:113908294 T/A cg00898013 chr13:113819073 PROZ -0.34 -6.21 -0.32 1.5e-9 Platelet distribution width; LIHC cis rs17376456 0.542 rs10476588 chr5:93208330 C/T cg25358565 chr5:93447407 FAM172A -0.79 -7.67 -0.38 1.77e-13 Diabetic retinopathy; LIHC cis rs3741798 1.000 rs118108016 chr12:12482820 C/A cg08615371 chr12:12503544 MANSC1 0.78 6.8 0.35 4.56e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs2806561 0.765 rs1612905 chr1:23510023 G/T cg19743168 chr1:23544995 NA 0.34 5.72 0.3 2.33e-8 Height; LIHC cis rs1371867 0.846 rs2919469 chr8:101233896 C/T cg06002616 chr8:101225028 SPAG1 -0.36 -6.01 -0.31 4.72e-9 Atrioventricular conduction; LIHC trans rs7246657 0.943 rs7252099 chr19:37933780 G/A cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg16132339 chr22:24313637 DDTL;DDT 0.72 13.91 0.6 3.57e-35 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618501 0.602 rs2071206 chr3:50160109 G/A cg21467203 chr3:49911342 NA 0.44 7.79 0.39 7.94e-14 Intelligence (multi-trait analysis); LIHC cis rs12048904 0.619 rs12239082 chr1:101330077 G/T cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.5 -7.36 -0.37 1.41e-12 Multiple sclerosis; LIHC cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg16423285 chr20:60520624 NA -0.53 -8.83 -0.43 5.49e-17 Obesity-related traits; LIHC cis rs35110281 0.592 rs6417729 chr21:44967202 A/C cg21573476 chr21:45109991 RRP1B -0.53 -9.81 -0.47 3.56e-20 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg12463550 chr7:65579703 CRCP 0.71 7.26 0.37 2.63e-12 Diabetic kidney disease; LIHC cis rs6782228 0.606 rs6807019 chr3:128405934 G/A cg16766828 chr3:128327626 NA -0.39 -6.2 -0.32 1.63e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg19800026 chr5:14492945 TRIO 0.41 6.42 0.33 4.58e-10 Longevity; LIHC cis rs17401966 0.931 rs2236678 chr1:10471789 A/T cg19773385 chr1:10388646 KIF1B -0.39 -6.35 -0.32 6.92e-10 Hepatocellular carcinoma; LIHC cis rs2204008 0.515 rs11495471 chr12:38027178 G/A cg26384229 chr12:38710491 ALG10B 0.85 10.57 0.5 9e-23 Bladder cancer; LIHC cis rs5769707 0.592 rs6009783 chr22:50011001 C/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.54 -0.42 4.44e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs597539 0.731 rs664229 chr11:68624483 C/G cg06028808 chr11:68637592 NA 0.44 5.8 0.3 1.48e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs8114671 0.562 rs6058120 chr20:33402829 A/G cg07148914 chr20:33460835 GGT7 0.58 8.61 0.42 2.7e-16 Height; LIHC cis rs1865760 0.927 rs6915834 chr6:25935427 A/C cg15691649 chr6:25882328 NA -0.39 -6.15 -0.32 2.11e-9 Height; LIHC cis rs6442522 0.809 rs2290537 chr3:15455717 A/G cg16303742 chr3:15540471 COLQ 0.37 5.91 0.3 8.44e-9 Uric acid levels; LIHC cis rs17401966 0.898 rs12757288 chr1:10323921 T/C cg15208524 chr1:10270712 KIF1B 0.39 5.99 0.31 5.17e-9 Hepatocellular carcinoma; LIHC cis rs2115630 0.936 rs11073663 chr15:85260268 A/G cg12501888 chr15:85177176 SCAND2 -0.5 -7.76 -0.39 9.75e-14 P wave terminal force; LIHC cis rs2997447 0.706 rs2783712 chr1:26429344 A/C cg19633962 chr1:26362018 EXTL1 -0.52 -5.91 -0.3 8.31e-9 QRS complex (12-leadsum); LIHC cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.92 0.3 7.89e-9 Schizophrenia; LIHC cis rs7772486 0.875 rs854148 chr6:146310979 G/C cg23711669 chr6:146136114 FBXO30 0.67 11.43 0.53 7.61e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.895 rs7782806 chr7:65657897 C/T cg11764359 chr7:65958608 NA -0.84 -14.15 -0.61 4.2500000000000003e-36 Aortic root size; LIHC cis rs4727027 0.933 rs12704062 chr7:148827865 G/A cg23583168 chr7:148888333 NA -0.74 -10.41 -0.49 3.17e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs875971 1.000 rs6961717 chr7:65587537 C/T cg18876405 chr7:65276391 NA -0.39 -6.91 -0.35 2.45e-11 Aortic root size; LIHC cis rs4727027 0.901 rs4727019 chr7:148822266 A/G cg23583168 chr7:148888333 NA -0.73 -10.37 -0.49 4.37e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs1538970 0.924 rs4660851 chr1:45843810 A/T cg24296786 chr1:45957014 TESK2 -0.5 -7.61 -0.38 2.69e-13 Platelet count; LIHC cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg12463550 chr7:65579703 CRCP 0.68 7.26 0.37 2.63e-12 Diabetic kidney disease; LIHC cis rs9916302 0.904 rs12452509 chr17:37574722 G/A cg00129232 chr17:37814104 STARD3 -0.4 -6.43 -0.33 4.4e-10 Glomerular filtration rate (creatinine); LIHC cis rs5758659 1.000 rs5758659 chr22:42622003 C/T cg19513890 chr22:42538836 CYP2D7P1 -0.41 -7.82 -0.39 6.53e-14 Cognitive function; LIHC cis rs3762637 0.941 rs9289192 chr3:122076115 C/G cg24169773 chr3:122142474 KPNA1 -0.49 -9.63 -0.46 1.42e-19 LDL cholesterol levels; LIHC trans rs1362756 0.958 rs8053277 chr16:51469726 T/C cg06577604 chr3:184279443 EPHB3 0.47 6.08 0.31 3.21e-9 Optic disc parameters;Optic disc area; LIHC cis rs3741404 0.620 rs11231722 chr11:63967770 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 12.46 0.56 1.21e-29 Platelet count; LIHC cis rs9326248 1.000 rs4938344 chr11:117003749 G/A cg15534755 chr11:117069859 TAGLN 0.36 6.07 0.31 3.45e-9 Blood protein levels; LIHC cis rs6964587 0.967 rs4626516 chr7:91807153 G/C cg17063962 chr7:91808500 NA 1.03 20.26 0.74 1.61e-60 Breast cancer; LIHC trans rs4714291 0.802 rs2983143 chr6:40044850 G/T cg02267698 chr19:7991119 CTXN1 -0.41 -6.87 -0.35 3.08e-11 Strep throat; LIHC cis rs6502050 0.835 rs8065556 chr17:80091176 G/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC cis rs4820539 0.966 rs5751590 chr22:23486830 A/C cg21100191 chr22:23484243 RTDR1 0.94 17.8 0.69 1.3e-50 Bone mineral density; LIHC cis rs2153535 0.580 rs9406165 chr6:8488837 C/T cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs1552244 0.572 rs57268864 chr3:10164233 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.85 8.49 0.42 6.5e-16 Alzheimer's disease; LIHC cis rs6061231 0.798 rs2427308 chr20:60969451 C/T cg06026331 chr20:60912101 LAMA5 0.49 6.5 0.33 2.83e-10 Colorectal cancer; LIHC cis rs7493 0.755 rs2375001 chr7:94964640 A/T cg17330251 chr7:94953956 PON1 -0.45 -5.98 -0.31 5.75e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs12497850 0.865 rs7649458 chr3:48920127 C/T cg07636037 chr3:49044803 WDR6 0.92 16.56 0.67 1.24e-45 Parkinson's disease; LIHC cis rs1005277 0.557 rs2983338 chr10:38550734 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.43 -6.34 -0.32 7.1e-10 Extrinsic epigenetic age acceleration; LIHC cis rs66887589 0.934 rs2389873 chr4:120554714 A/G cg09307838 chr4:120376055 NA -0.45 -6.69 -0.34 9.17e-11 Diastolic blood pressure; LIHC cis rs796364 0.577 rs7574287 chr2:200680999 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.16 0.32 2.03e-9 Schizophrenia; LIHC cis rs66569888 0.632 rs6728600 chr2:106898653 G/T cg16099169 chr2:106886729 NA -0.9 -9.3 -0.45 1.7e-18 Facial morphology (factor 23); LIHC cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg12310025 chr6:25882481 NA -0.87 -12.51 -0.56 7.67e-30 Blood metabolite levels; LIHC cis rs9457247 1.000 rs422094 chr6:167397033 C/G cg23791538 chr6:167370224 RNASET2 -0.67 -11.56 -0.53 2.49e-26 Crohn's disease; LIHC cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg17971929 chr21:40555470 PSMG1 0.8 9.13 0.44 6.23e-18 Cognitive function; LIHC cis rs2404602 0.583 rs2139190 chr15:76555539 G/C cg03037974 chr15:76606532 NA 0.88 22.78 0.78 1.53e-70 Blood metabolite levels; LIHC cis rs2455601 0.882 rs11042115 chr11:8926679 A/C cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -6.17 -0.32 1.91e-9 Schizophrenia; LIHC cis rs7945718 0.967 rs10831906 chr11:12783042 C/T cg25843174 chr11:12811716 TEAD1 0.35 7.91 0.39 3.53e-14 Educational attainment (years of education); LIHC cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg02290350 chr8:58132656 NA 0.45 9.06 0.44 9.93e-18 Developmental language disorder (linguistic errors); LIHC cis rs752010 0.714 rs6664708 chr1:42083070 G/A cg06885757 chr1:42089581 HIVEP3 0.3 6.36 0.33 6.6e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs722599 0.683 rs7160852 chr14:75239424 T/C cg08847533 chr14:75593920 NEK9 0.54 8.22 0.41 4.24e-15 IgG glycosylation; LIHC cis rs5769765 0.565 rs8137232 chr22:50256885 G/C cg22709217 chr22:50311962 ALG12;CRELD2 0.58 5.81 0.3 1.44e-8 Schizophrenia; LIHC cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.13e-9 Menopause (age at onset); LIHC cis rs56146971 0.670 rs12590074 chr14:91867390 T/G cg16433844 chr14:91963127 SMEK1 -0.51 -6.06 -0.31 3.58e-9 Alzheimer disease and age of onset; LIHC cis rs3823572 0.564 rs2971962 chr7:133639770 G/A cg03336402 chr7:133662267 EXOC4 0.48 5.74 0.3 2.07e-8 Intelligence (multi-trait analysis); LIHC cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.18 11.45 0.53 6.59e-26 Platelet count; LIHC cis rs9467773 0.935 rs9461270 chr6:26544110 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.9 0.6 4.02e-35 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg06873352 chr17:61820015 STRADA 0.6 9.32 0.45 1.51e-18 Height; LIHC cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs1003719 0.751 rs55740803 chr21:38542761 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs6840360 0.550 rs6816471 chr4:152494869 A/G cg22705602 chr4:152727874 NA -0.34 -6.52 -0.33 2.59e-10 Intelligence (multi-trait analysis); LIHC cis rs9733 0.569 rs11588404 chr1:150688529 C/A cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC trans rs73186030 1.000 rs73186044 chr3:122028476 G/T cg13973942 chr17:977984 ABR 0.47 6.06 0.31 3.6e-9 Serum parathyroid hormone levels; LIHC cis rs951366 0.617 rs823075 chr1:205774897 C/T cg14159672 chr1:205819179 PM20D1 0.86 12.22 0.55 9.54e-29 Menarche (age at onset); LIHC cis rs2243480 0.901 rs35823062 chr7:65965821 A/G cg07424592 chr7:64974309 NA 0.78 9.03 0.44 1.23e-17 Diabetic kidney disease; LIHC cis rs1005277 0.579 rs1548255 chr10:38417193 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.96 -0.31 6.38e-9 Extrinsic epigenetic age acceleration; LIHC trans rs2744203 1.000 rs72610883 chr6:104640613 A/G cg27088726 chr16:83171155 CDH13 -0.46 -6.08 -0.31 3.14e-9 IgG glycosylation; LIHC cis rs743757 1.000 rs734767 chr3:50431410 C/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.51 8.18 0.4 5.49e-15 Diastolic blood pressure; LIHC cis rs600806 0.850 rs3931560 chr1:109966718 A/C cg16275483 chr1:110013120 SYPL2 -0.49 -6.04 -0.31 4.11e-9 Intelligence (multi-trait analysis); LIHC cis rs7095944 0.584 rs4962692 chr10:126424823 G/A cg08799069 chr10:126477246 METTL10 -0.34 -5.98 -0.31 5.75e-9 Asthma; LIHC cis rs739401 0.611 rs402276 chr11:3051404 C/G cg25174290 chr11:3078921 CARS 0.61 9.23 0.45 2.86e-18 Longevity; LIHC cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg25072359 chr17:41440525 NA 0.38 6.03 0.31 4.34e-9 Menopause (age at onset); LIHC cis rs9948 0.500 rs62152903 chr2:97570377 T/C cg26665480 chr2:98280029 ACTR1B -0.57 -5.79 -0.3 1.57e-8 Erectile dysfunction and prostate cancer treatment; LIHC cis rs5769765 0.954 rs5769762 chr22:50264042 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs7772486 0.875 rs9390371 chr6:146363180 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.77 0.3 1.77e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7223966 1.000 rs8067431 chr17:61817048 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 7.01 0.35 1.26e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7107174 1.000 rs10899451 chr11:77991222 A/C cg02023728 chr11:77925099 USP35 0.51 9.74 0.47 6.19e-20 Testicular germ cell tumor; LIHC cis rs13108904 0.846 rs12643212 chr4:1224948 A/G cg00684032 chr4:1343700 KIAA1530 0.46 6.64 0.34 1.24e-10 Obesity-related traits; LIHC cis rs17539620 0.519 rs4077066 chr6:154838448 C/G cg20019720 chr6:154832845 CNKSR3 0.45 7.18 0.36 4.37e-12 Lipoprotein (a) levels; LIHC cis rs2370759 1.000 rs75984055 chr10:32591276 T/C cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs12701220 0.595 rs12532837 chr7:1122851 T/A cg02733842 chr7:1102375 C7orf50 -0.65 -7.12 -0.36 6.34e-12 Bronchopulmonary dysplasia; LIHC cis rs3736594 0.918 rs9967838 chr2:27968454 A/C cg27432699 chr2:27873401 GPN1 -0.43 -6.68 -0.34 9.56e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs4243830 0.850 rs2412309 chr1:6603151 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.95 -12.12 -0.55 2.25e-28 Body mass index; LIHC cis rs1003719 0.762 rs1015551 chr21:38449510 G/A cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 6.97e-29 Eye color traits; LIHC cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.22 0.32 1.43e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7927592 0.871 rs113020558 chr11:68296832 G/A cg20283391 chr11:68216788 NA -0.53 -7.86 -0.39 5.21e-14 Total body bone mineral density; LIHC cis rs12477438 0.765 rs62154638 chr2:99639584 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.56 -0.5 9.46e-23 Chronic sinus infection; LIHC cis rs151997 0.962 rs27271 chr5:50183369 A/G cg06027927 chr5:50259733 NA 0.56 7.66 0.38 1.9e-13 Callous-unemotional behaviour; LIHC cis rs9517320 1.000 rs7996093 chr13:99133092 T/C cg07423050 chr13:99094983 FARP1 0.37 6.19 0.32 1.71e-9 Longevity; LIHC cis rs1035144 0.505 rs6574617 chr14:81457615 G/A cg06600135 chr14:81408086 NA -0.42 -7.35 -0.37 1.51e-12 Male sexual orientation; LIHC cis rs73001065 0.636 rs8182472 chr19:19539891 A/G cg03709012 chr19:19516395 GATAD2A 0.86 9.43 0.45 6.48e-19 LDL cholesterol; LIHC cis rs2832191 0.716 rs8132085 chr21:30501389 G/T cg08807101 chr21:30365312 RNF160 -0.74 -10.38 -0.49 4.13e-22 Dental caries; LIHC cis rs7537052 0.669 rs475591 chr1:36642420 T/C cg24686825 chr1:36642396 MAP7D1 -0.7 -11.51 -0.53 3.92e-26 Schizophrenia; LIHC cis rs644799 0.710 rs522536 chr11:95528714 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.76 13.11 0.58 4.33e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.49 7.17 0.36 4.7e-12 Prostate cancer; LIHC cis rs16828019 0.852 rs34386859 chr1:41564024 C/T cg03962019 chr1:41807865 NA 0.49 7.13 0.36 6.13e-12 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.708 rs10984992 chr9:123473416 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.04 0.51 1.95e-24 Hip circumference adjusted for BMI; LIHC cis rs2075371 0.931 rs1646697 chr7:133999930 G/A cg11752832 chr7:134001865 SLC35B4 0.52 7.65 0.38 2.01e-13 Mean platelet volume; LIHC cis rs4654899 1.000 rs6697555 chr1:21287938 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.94 0.31 7.19e-9 Superior frontal gyrus grey matter volume; LIHC cis rs2637030 0.515 rs1532163 chr5:52856716 A/G cg06476337 chr5:52856530 NDUFS4 0.43 6.76 0.34 6.13e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC trans rs12478296 1.000 rs73007140 chr2:243010756 T/C cg01596870 chr19:55963115 NA -0.67 -9.63 -0.46 1.36e-19 Obesity-related traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08266417 chr2:201450575 AOX1 -0.53 -6.46 -0.33 3.69e-10 Systolic blood pressure; LIHC cis rs7582720 1.000 rs72926779 chr2:203805929 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10861342 1.000 rs1345095 chr12:105471577 C/T cg23923672 chr12:105501055 KIAA1033 0.69 8.02 0.4 1.68e-14 IgG glycosylation; LIHC cis rs11098499 0.909 rs17046118 chr4:120387496 T/G cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs1062177 1.000 rs2915882 chr5:151145436 T/C cg00977110 chr5:151150581 G3BP1 0.56 7.12 0.36 6.6e-12 Preschool internalizing problems; LIHC cis rs16854884 0.683 rs10935505 chr3:143777966 T/C cg06585982 chr3:143692056 C3orf58 0.48 6.76 0.34 6.15e-11 Economic and political preferences (feminism/equality); LIHC cis rs9443189 0.526 rs10943250 chr6:76208445 C/G cg01950844 chr6:76311363 SENP6 0.9 10.74 0.5 2.17e-23 Prostate cancer; LIHC trans rs950169 0.579 rs11633088 chr15:84672181 A/T cg24036039 chr1:3397125 ARHGEF16 -0.42 -7.15 -0.36 5.3e-12 Schizophrenia; LIHC cis rs2380220 0.541 rs9285413 chr6:96023439 G/A cg23517279 chr6:96025343 MANEA 0.57 5.78 0.3 1.7e-8 Behavioural disinhibition (generation interaction); LIHC cis rs875971 1.000 rs11974264 chr7:65647582 C/G cg18876405 chr7:65276391 NA -0.38 -6.73 -0.34 7.21e-11 Aortic root size; LIHC cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg04083430 chr16:4736063 MGRN1 -0.42 -5.79 -0.3 1.59e-8 Schizophrenia; LIHC cis rs6988636 1.000 rs60827294 chr8:124187842 T/C cg15893493 chr8:124194847 FAM83A 0.89 8.31 0.41 2.26e-15 Urinary uromodulin levels; LIHC cis rs2635047 0.967 rs2684820 chr18:44664304 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.47 6.21 0.32 1.57e-9 Educational attainment; LIHC cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg13393036 chr8:95962371 TP53INP1 -0.37 -8.63 -0.42 2.4e-16 Type 2 diabetes; LIHC cis rs6754311 0.731 rs2322660 chr2:136557319 A/G cg07169764 chr2:136633963 MCM6 0.67 10.04 0.48 5.65e-21 Mosquito bite size; LIHC cis rs765787 0.530 rs28756676 chr15:45540360 G/A cg24006582 chr15:45444508 DUOX1 -0.5 -7.25 -0.36 2.88e-12 Uric acid levels; LIHC cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.47 6.48 0.33 3.29e-10 Bipolar disorder; LIHC cis rs17384381 1.000 rs12140935 chr1:85855716 G/A cg16011679 chr1:85725395 C1orf52 0.83 8.62 0.42 2.57e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs2239547 0.618 rs3733047 chr3:52871929 A/G cg11645453 chr3:52864694 ITIH4 -0.33 -8.6 -0.42 2.84e-16 Schizophrenia; LIHC cis rs8062405 1.000 rs11861174 chr16:28871989 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.0 -23.99 -0.79 2.76e-75 Prudent dietary pattern; LIHC cis rs79387448 0.745 rs72995652 chr2:103171651 C/A cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs11098499 0.820 rs11737395 chr4:120520704 C/G cg09307838 chr4:120376055 NA 0.75 11.68 0.53 9.81e-27 Corneal astigmatism; LIHC cis rs9911578 1.000 rs9897326 chr17:56902297 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.83 -0.43 5.44e-17 Intelligence (multi-trait analysis); LIHC cis rs7729447 0.813 rs4867470 chr5:32692536 C/A cg16267343 chr5:32710456 NPR3 0.47 5.78 0.3 1.69e-8 Blood pressure; LIHC cis rs1552244 0.882 rs13074282 chr3:10024699 T/G cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs3096299 0.582 rs12935119 chr16:89542874 A/T cg06640241 chr16:89574553 SPG7 0.63 10.46 0.49 2.12e-22 Multiple myeloma (IgH translocation); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21905229 chr20:32031732 SNTA1 -0.54 -6.31 -0.32 8.59e-10 Systolic blood pressure; LIHC cis rs9326248 0.954 rs8521 chr11:117067699 C/T cg10130564 chr11:117069849 TAGLN 0.37 6.17 0.32 1.96e-9 Blood protein levels; LIHC cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg20607798 chr8:58055168 NA 0.59 6.94 0.35 1.92e-11 Developmental language disorder (linguistic errors); LIHC cis rs9399135 1.000 rs4895435 chr6:135293463 C/A cg22676075 chr6:135203613 NA 0.38 6.14 0.31 2.33e-9 Red blood cell count; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg07264154 chr3:142546513 PCOLCE2 0.52 6.22 0.32 1.46e-9 Mean platelet volume; LIHC cis rs11690935 0.959 rs7604918 chr2:172588094 G/A cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.71 -0.69 2.99e-50 Schizophrenia; LIHC cis rs11148252 0.967 rs4286007 chr13:53022518 A/G cg00495681 chr13:53174319 NA 0.41 6.77 0.34 5.55e-11 Lewy body disease; LIHC cis rs9911578 0.933 rs74370218 chr17:57095212 C/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.95 -0.7 3.2e-51 Intelligence (multi-trait analysis); LIHC cis rs950169 0.922 rs2033284 chr15:84946273 C/T cg03959625 chr15:84868606 LOC388152 0.46 6.51 0.33 2.67e-10 Schizophrenia; LIHC cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs870825 0.616 rs57086463 chr4:185639525 G/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs9549367 0.713 rs3024761 chr13:113824090 C/G cg18105134 chr13:113819100 PROZ 0.74 12.38 0.56 2.36e-29 Platelet distribution width; LIHC cis rs12048904 0.964 rs3188491 chr1:101338482 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.49 8.31 0.41 2.25e-15 Multiple sclerosis; LIHC cis rs12935418 0.672 rs1453327 chr16:81048564 A/C cg08265926 chr16:81039227 CENPN;C16orf61 -0.33 -5.78 -0.3 1.66e-8 Mean corpuscular volume; LIHC cis rs2637266 0.905 rs4357630 chr10:78382883 T/G cg18941641 chr10:78392320 NA 0.29 6.16 0.32 2.01e-9 Pulmonary function; LIHC cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg02290350 chr8:58132656 NA 0.47 9.27 0.45 2.1e-18 Developmental language disorder (linguistic errors); LIHC trans rs7714584 1.000 rs7734928 chr5:150256613 G/A cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs12824058 0.831 rs1390849 chr12:130811547 A/G cg24838063 chr12:130822603 PIWIL1 0.67 9.96 0.47 1.1e-20 Menopause (age at onset); LIHC cis rs5758659 1.000 rs134873 chr22:42657566 T/G cg19513890 chr22:42538836 CYP2D7P1 -0.38 -7.39 -0.37 1.11e-12 Cognitive function; LIHC cis rs6138458 0.887 rs227622 chr20:24910597 T/C cg26195577 chr20:24973756 C20orf3 1.13 14.83 0.63 9.14e-39 Blood protein levels; LIHC cis rs1005277 0.579 rs2472176 chr10:38382921 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs4684776 0.867 rs13058769 chr3:11342305 A/G cg00170343 chr3:11313890 ATG7 -0.53 -7.28 -0.37 2.31e-12 Small vessel stroke; LIHC cis rs2412488 1.000 rs931182 chr4:54243230 T/C cg22241045 chr4:54363911 LNX1 -0.46 -7.29 -0.37 2.19e-12 DNA methylation (variation); LIHC cis rs9549367 0.789 rs9549365 chr13:113907391 C/T cg00898013 chr13:113819073 PROZ 0.33 5.84 0.3 1.23e-8 Platelet distribution width; LIHC cis rs1198872 0.558 rs10929699 chr2:10918209 C/T cg10157359 chr2:10953004 PDIA6 -0.52 -7.07 -0.36 8.74e-12 Cardiac Troponin-T levels; LIHC cis rs9486715 0.809 rs9486467 chr6:96971803 C/T cg06623918 chr6:96969491 KIAA0776 0.86 15.42 0.64 4.39e-41 Headache; LIHC cis rs1355223 0.583 rs2116085 chr11:34884001 C/A cg11058730 chr11:34937778 PDHX;APIP 0.77 14.12 0.61 5.45e-36 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs703842 0.616 rs10783851 chr12:58231155 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.69 -9.55 -0.46 2.65e-19 Multiple sclerosis; LIHC cis rs11105306 1 rs11105306 chr12:89897388 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.59 -0.38 3.13e-13 NT-proBNP levels in acute coronary syndrome; LIHC cis rs17213078 0.602 rs4851113 chr2:106747009 G/C cg16099169 chr2:106886729 NA 0.43 6.53 0.33 2.36e-10 Facial morphology (factor 23); LIHC cis rs636291 0.517 rs672606 chr1:10526144 G/A cg17425144 chr1:10567563 PEX14 0.52 10.11 0.48 3.5e-21 Prostate cancer; LIHC cis rs1801251 1.000 rs6724117 chr2:233593660 T/G cg25237894 chr2:233734115 C2orf82 0.57 11.12 0.52 1.03e-24 Coronary artery disease; LIHC cis rs4919087 0.748 rs1687369 chr10:98976923 G/A cg25902810 chr10:99078978 FRAT1 -0.56 -6.36 -0.33 6.41e-10 Monocyte count; LIHC cis rs7116495 0.609 rs7126394 chr11:71685429 A/G cg10381502 chr11:71823885 C11orf51 -1.02 -8.51 -0.42 5.38e-16 Severe influenza A (H1N1) infection; LIHC cis rs78545713 0.649 rs74928264 chr6:26224343 C/G cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs9911578 0.935 rs6503878 chr17:56884581 T/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.69 -0.43 1.55e-16 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 3.15e-30 Menopause (age at onset); LIHC trans rs7395662 0.591 rs4882093 chr11:48530820 G/A cg15704280 chr7:45808275 SEPT13 -0.45 -6.81 -0.35 4.36e-11 HDL cholesterol; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.88 0.39 4.49e-14 Prudent dietary pattern; LIHC cis rs1448094 0.512 rs12305828 chr12:86249153 C/G cg02569458 chr12:86230093 RASSF9 0.46 6.19 0.32 1.76e-9 Major depressive disorder; LIHC cis rs2070488 0.965 rs6805386 chr3:38557921 T/C cg24069376 chr3:38537580 EXOG -0.39 -7.11 -0.36 6.72e-12 Electrocardiographic conduction measures; LIHC cis rs7309 0.935 rs1921309 chr2:162048975 T/A cg16506815 chr2:162101123 NA 0.57 9.86 0.47 2.47e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs1005277 0.522 rs289648 chr10:37971837 T/C cg25427524 chr10:38739819 LOC399744 -0.61 -11.4 -0.52 9.82e-26 Extrinsic epigenetic age acceleration; LIHC cis rs17106184 1.000 rs72902778 chr1:51276715 A/G cg07174182 chr1:51127561 FAF1 -0.65 -6.99 -0.35 1.46e-11 Type 2 diabetes; LIHC cis rs66573146 0.572 rs66819208 chr4:6946128 A/G cg15105060 chr4:7024189 TBC1D14 -0.7 -6.31 -0.32 8.73e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg11987759 chr7:65425863 GUSB -0.39 -6.09 -0.31 3.1e-9 Aortic root size; LIHC cis rs7412746 0.658 rs4970987 chr1:150949682 T/C cg18016565 chr1:150552671 MCL1 0.52 9.57 0.46 2.2e-19 Melanoma; LIHC cis rs9948 0.655 rs17119564 chr2:97384728 G/A cg01990225 chr2:97406019 LMAN2L -0.8 -6.21 -0.32 1.53e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg07061783 chr6:25882402 NA -0.88 -12.24 -0.55 8.15e-29 Urate levels; LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg02869306 chr7:64672164 INTS4L1 -0.3 -6.42 -0.33 4.47e-10 Calcium levels; LIHC cis rs11608355 0.545 rs34737994 chr12:109901621 C/T cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs1865760 0.892 rs6456705 chr6:25936056 G/A cg12310025 chr6:25882481 NA -0.42 -6.32 -0.32 8.09e-10 Height; LIHC cis rs6964587 0.869 rs4729010 chr7:91486751 G/A cg17063962 chr7:91808500 NA -0.95 -18.2 -0.7 3.08e-52 Breast cancer; LIHC cis rs7703051 0.513 rs59014134 chr5:74589385 C/T cg19683494 chr5:74908142 NA 0.68 8.91 0.43 3.09e-17 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg08219700 chr8:58056026 NA 0.45 5.73 0.3 2.25e-8 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.643 rs520095 chr2:219329485 C/T cg02985541 chr2:219472218 PLCD4 0.47 8.94 0.44 2.53e-17 Mean corpuscular hemoglobin concentration; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg26888861 chr11:62521812 ZBTB3 -0.48 -7.99 -0.4 2.07e-14 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11098499 0.866 rs12499602 chr4:120284387 T/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.29 0.55 5.3e-29 Prudent dietary pattern; LIHC cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg13607699 chr17:42295918 UBTF 0.44 7.09 0.36 7.67e-12 Total body bone mineral density; LIHC cis rs3768617 0.811 rs12563494 chr1:183039698 G/A ch.1.3577855R chr1:183094577 LAMC1 0.48 7.65 0.38 2.08e-13 Fuchs's corneal dystrophy; LIHC cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg07414643 chr4:187882934 NA 0.24 6.02 0.31 4.61e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9527 0.615 rs7917295 chr10:104701187 A/G cg15744005 chr10:104629667 AS3MT -0.29 -5.73 -0.3 2.16e-8 Arsenic metabolism; LIHC cis rs826838 1.000 rs11169031 chr12:39056738 T/C cg13010199 chr12:38710504 ALG10B 0.53 6.5 0.33 2.79e-10 Heart rate; LIHC cis rs9611565 0.649 rs126092 chr22:42178441 A/G cg03806693 chr22:41940476 POLR3H 0.82 9.65 0.46 1.19e-19 Vitiligo; LIHC cis rs79149102 0.579 rs58294763 chr15:75299768 G/A cg17294928 chr15:75287854 SCAMP5 -0.52 -6.67 -0.34 1.06e-10 Lung cancer; LIHC trans rs6598955 0.671 rs41285347 chr1:26644399 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.71 -7.22 -0.36 3.46e-12 Obesity-related traits; LIHC trans rs12310956 0.532 rs11608842 chr12:33951121 C/T cg26384229 chr12:38710491 ALG10B 0.43 6.07 0.31 3.41e-9 Morning vs. evening chronotype; LIHC cis rs2455601 0.882 rs11042106 chr11:8896083 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.46 6.29 0.32 9.53e-10 Schizophrenia; LIHC cis rs2204008 0.837 rs11495548 chr12:38076756 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs8067354 0.830 rs57510610 chr17:57889406 T/A cg13753209 chr17:57696993 CLTC 0.59 9.03 0.44 1.28e-17 Hemoglobin concentration; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg07677032 chr17:61819896 STRADA 0.41 5.76 0.3 1.84e-8 Prudent dietary pattern; LIHC cis rs1448094 0.506 rs61930640 chr12:86173333 T/C cg02569458 chr12:86230093 RASSF9 0.45 5.85 0.3 1.14e-8 Major depressive disorder; LIHC cis rs17286411 0.750 rs35619990 chr16:71949266 C/T cg06353428 chr16:71660113 MARVELD3 0.55 6.87 0.35 3.06e-11 Blood protein levels; LIHC cis rs362296 0.661 rs3095078 chr4:3265479 C/T cg06533319 chr4:3265114 C4orf44 0.33 6.5 0.33 2.91e-10 Parental longevity (mother's age at death); LIHC cis rs9349203 1 rs9349203 chr6:41893323 G/A cg17623882 chr6:41773611 USP49 -0.51 -7.74 -0.39 1.12e-13 Menarche (age at onset); LIHC cis rs10088262 0.591 rs13270541 chr8:124794849 G/A cg02993010 chr8:124780839 FAM91A1 -0.48 -6.16 -0.32 2.08e-9 Pancreatic cancer; LIHC cis rs17685 0.725 rs6467993 chr7:75719350 G/A cg01364799 chr7:75623366 TMEM120A -0.48 -7.2 -0.36 3.79e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7326068 0.524 rs7998500 chr13:21159000 A/G cg27499820 chr13:21296301 IL17D 0.37 5.9 0.3 8.93e-9 Schizophrenia, bipolar disorder and depression (combined); LIHC cis rs7116495 1.000 rs515358 chr11:71562302 G/C cg26138937 chr11:71823887 C11orf51 0.65 6.27 0.32 1.11e-9 Severe influenza A (H1N1) infection; LIHC cis rs4862750 0.914 rs9995391 chr4:187873749 A/T cg22105103 chr4:187893119 NA -0.32 -7.62 -0.38 2.45e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs10751667 0.666 rs4074234 chr11:977715 C/G cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs929354 0.935 rs1182392 chr7:157036200 C/T cg17757837 chr7:157058334 UBE3C -0.77 -13.13 -0.58 3.65e-32 Body mass index; LIHC cis rs4638749 0.627 rs6542753 chr2:108815852 T/A cg25838818 chr2:108905173 SULT1C2 -0.39 -6.71 -0.34 8.07e-11 Blood pressure; LIHC cis rs2439831 1.000 rs2584725 chr15:43793135 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.68 0.59 2.85e-34 Lung cancer in ever smokers; LIHC cis rs7903847 0.596 rs11189203 chr10:99159096 C/A cg08345082 chr10:99160200 RRP12 -0.4 -6.76 -0.34 5.81e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs6762477 0.748 rs11717349 chr3:50223977 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.58 -9.09 -0.44 8.35e-18 Menarche (age at onset); LIHC cis rs4925386 0.840 rs6143024 chr20:60914229 A/G cg06026331 chr20:60912101 LAMA5 0.65 9.62 0.46 1.5700000000000001e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs76419734 0.510 rs2216516 chr4:106749857 G/C cg24545054 chr4:106630052 GSTCD;INTS12 -0.71 -7.32 -0.37 1.81e-12 Post bronchodilator FEV1; LIHC cis rs936229 0.668 rs67411922 chr15:75187612 A/G cg14664628 chr15:75095509 CSK -0.72 -9.63 -0.46 1.44e-19 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs2066819 1.000 rs75598973 chr12:56746558 C/T cg26734620 chr12:56694298 CS 1.21 10.14 0.48 2.67e-21 Psoriasis vulgaris; LIHC cis rs782590 1.000 rs782594 chr2:55844445 T/C cg03859395 chr2:55845619 SMEK2 0.93 16.59 0.67 9.1e-46 Metabolic syndrome; LIHC cis rs12478296 1.000 rs11899408 chr2:243014630 A/G cg06360820 chr2:242988706 NA -0.91 -12.47 -0.56 1.08e-29 Obesity-related traits; LIHC cis rs9381040 0.748 rs9357348 chr6:41154232 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.57 -0.33 1.92e-10 Alzheimer's disease (late onset); LIHC cis rs10791323 0.582 rs2723613 chr11:133706696 G/A cg06766960 chr11:133703094 NA -0.66 -10.75 -0.5 2e-23 Childhood ear infection; LIHC cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg02951883 chr7:2050386 MAD1L1 -0.85 -15.28 -0.64 1.5e-40 Bipolar disorder and schizophrenia; LIHC cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg03517284 chr6:25882590 NA -0.6 -8.51 -0.42 5.64e-16 Blood metabolite levels; LIHC cis rs1892700 0.764 rs8971 chr21:34883618 T/C cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.97e-8 Educational attainment; LIHC cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg27297192 chr10:134578999 INPP5A 0.56 7.73 0.39 1.19e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2463822 0.858 rs2513077 chr11:62105925 A/G cg06239285 chr11:62104954 ASRGL1 -0.93 -7.04 -0.36 1.06e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg14166365 chr9:126165469 DENND1A;MIR601 -0.36 -6.2 -0.32 1.66e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg22618164 chr12:122356400 WDR66 0.57 8.28 0.41 2.81e-15 Mean corpuscular volume; LIHC cis rs1878931 0.696 rs35175748 chr16:3445427 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.99 22.61 0.77 7.14e-70 Body mass index (adult); LIHC cis rs1949733 0.598 rs4696838 chr4:8540349 A/G cg11789530 chr4:8429930 ACOX3 -0.58 -8.2 -0.41 4.96e-15 Response to antineoplastic agents; LIHC cis rs244731 0.959 rs4976677 chr5:176629546 G/A cg16006841 chr5:176797999 RGS14 -0.62 -5.99 -0.31 5.26e-9 Urate levels in lean individuals; LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg14159672 chr1:205819179 PM20D1 0.73 10.33 0.49 6.15e-22 Menarche (age at onset); LIHC trans rs11098499 0.955 rs35197422 chr4:120169314 T/G cg25214090 chr10:38739885 LOC399744 0.52 7.93 0.39 3.24e-14 Corneal astigmatism; LIHC cis rs7635838 0.617 rs346085 chr3:11282724 T/C cg00170343 chr3:11313890 ATG7 0.59 9.42 0.45 6.98e-19 HDL cholesterol; LIHC cis rs10256972 0.869 rs4720158 chr7:1040325 A/G cg07092213 chr7:1199455 ZFAND2A -0.38 -5.74 -0.3 2.06e-8 Longevity;Endometriosis; LIHC trans rs61931739 0.500 rs34997501 chr12:34549828 C/G cg26384229 chr12:38710491 ALG10B 0.79 9.68 0.46 9.64e-20 Morning vs. evening chronotype; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01181084 chr8:43059863 NA 0.47 6.74 0.34 6.78e-11 Longevity; LIHC cis rs11671005 0.652 rs11670864 chr19:59030580 G/T cg25952890 chr19:58913133 NA 0.62 6.19 0.32 1.69e-9 Mean platelet volume; LIHC cis rs17102423 0.755 rs8009396 chr14:65573438 C/G cg11161011 chr14:65562177 MAX -0.58 -8.21 -0.41 4.71e-15 Obesity-related traits; LIHC cis rs7503807 0.651 rs901065 chr17:78599655 G/T cg09596252 chr17:78655493 RPTOR 0.36 6.1 0.31 2.82e-9 Obesity; LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg21747090 chr2:27597821 SNX17 -0.41 -6.1 -0.31 2.94e-9 Total body bone mineral density; LIHC cis rs12602486 1.000 rs78673779 chr17:42217936 G/A cg13607699 chr17:42295918 UBTF -0.72 -6.27 -0.32 1.12e-9 Glycated hemoglobin levels; LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg24209194 chr3:40518798 ZNF619 0.56 8.11 0.4 9.34e-15 Renal cell carcinoma; LIHC cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg19539972 chr4:7069911 GRPEL1 0.68 10.03 0.48 6.31e-21 Monocyte percentage of white cells; LIHC trans rs916888 0.773 rs538628 chr17:44787313 G/C cg07870213 chr5:140052090 DND1 1.03 10.46 0.49 2.09e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11227306 0.934 rs10896056 chr11:65587905 A/G cg00576331 chr11:65640516 EFEMP2 -0.41 -5.92 -0.3 8.04e-9 DNA methylation (variation); LIHC cis rs10876993 0.890 rs2619441 chr12:58083015 C/A cg15848620 chr12:58087721 OS9 -0.58 -7.97 -0.4 2.37e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs72772090 0.634 rs17401901 chr5:96091925 C/T cg17330273 chr5:96107758 CAST;ERAP1 -0.63 -7.08 -0.36 8.02e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12477438 0.520 rs4340581 chr2:99725025 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs4820294 0.646 rs9622675 chr22:38053665 G/T cg10587741 chr22:38071170 LGALS1 0.44 7.95 0.39 2.72e-14 Fat distribution (HIV); LIHC cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg03452623 chr4:187889614 NA -0.33 -8.48 -0.42 7.1e-16 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15356674 chr10:79471309 NA 0.41 6.05 0.31 3.77e-9 Pancreatic cancer; LIHC cis rs6500602 0.927 rs7200817 chr16:4480598 G/C cg08645402 chr16:4508243 NA 0.38 7.2 0.36 3.94e-12 Schizophrenia; LIHC cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg25894440 chr7:65020034 NA -0.52 -5.79 -0.3 1.6e-8 Diabetic kidney disease; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg11060661 chr22:24314208 DDT;DDTL 0.58 9.71 0.47 7.38e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs60843830 1.000 rs4497901 chr2:239969 C/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.54 0.46 2.78e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs13108904 0.539 rs11247997 chr4:1361057 T/C cg13395646 chr4:1353034 KIAA1530 -0.91 -13.68 -0.59 2.89e-34 Obesity-related traits; LIHC trans rs459571 0.959 rs456205 chr9:136911146 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.57 -8.72 -0.43 1.24e-16 Platelet distribution width; LIHC trans rs4820294 0.669 rs7287358 chr22:38054403 A/G cg19894588 chr14:64061835 NA -0.47 -7.44 -0.37 8.1e-13 Fat distribution (HIV); LIHC cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg02187348 chr16:89574699 SPG7 0.65 10.55 0.5 1.03e-22 Multiple myeloma (IgH translocation); LIHC cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg12463550 chr7:65579703 CRCP -0.67 -6.86 -0.35 3.29e-11 Diabetic kidney disease; LIHC cis rs897984 0.542 rs7294 chr16:31102321 A/G cg02466173 chr16:30829666 NA 0.42 7.45 0.37 7.54e-13 Dementia with Lewy bodies; LIHC cis rs782590 0.967 rs782588 chr2:55841640 T/C cg03859395 chr2:55845619 SMEK2 0.93 16.56 0.67 1.2e-45 Metabolic syndrome; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03811519 chr9:134001305 NUP214 0.42 6.14 0.32 2.32e-9 Pancreatic cancer; LIHC cis rs11711311 1.000 rs12695295 chr3:113474866 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.4 -7.56 -0.38 3.67e-13 IgG glycosylation; LIHC cis rs6752107 0.967 rs36001488 chr2:234185267 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.24 0.41 3.62e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7843479 0.601 rs6557712 chr8:21826421 C/T cg17168535 chr8:21777572 XPO7 0.58 10.13 0.48 2.96e-21 Mean corpuscular volume; LIHC cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg06634786 chr22:41940651 POLR3H -0.83 -8.95 -0.44 2.36e-17 Vitiligo; LIHC cis rs4631830 0.720 rs11004422 chr10:51498336 A/G cg20129853 chr10:51489980 NA 0.4 8.57 0.42 3.7e-16 Prostate-specific antigen levels; LIHC cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg03806693 chr22:41940476 POLR3H -1.05 -11.66 -0.53 1.15e-26 Vitiligo; LIHC cis rs7116495 1.000 rs609181 chr11:71569672 T/C cg26138937 chr11:71823887 C11orf51 0.68 6.64 0.34 1.24e-10 Severe influenza A (H1N1) infection; LIHC cis rs6430585 0.528 rs115469964 chr2:136696608 A/C cg07305463 chr2:136567211 LCT -0.38 -5.88 -0.3 9.67e-9 Corneal structure; LIHC cis rs734999 0.588 rs3001837 chr1:2532506 G/A cg18854424 chr1:2615690 NA -0.32 -7.11 -0.36 6.83e-12 Ulcerative colitis; LIHC cis rs6499255 1.000 rs73579497 chr16:69824150 C/G cg15192750 chr16:69999425 NA 0.44 6.65 0.34 1.14e-10 IgE levels; LIHC cis rs7020830 0.931 rs13288178 chr9:37107799 A/G cg14294708 chr9:37120828 ZCCHC7 1.12 24.79 0.8 2.18e-78 Schizophrenia; LIHC cis rs2153535 0.580 rs7745043 chr6:8513507 T/C cg21535247 chr6:8435926 SLC35B3 0.61 7.97 0.4 2.37e-14 Motion sickness; LIHC cis rs921968 0.541 rs642520 chr2:219423605 A/G cg02176678 chr2:219576539 TTLL4 -0.53 -7.38 -0.37 1.25e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs2467099 0.735 rs55793071 chr17:73909948 C/T cg08125733 chr17:73851984 WBP2 0.45 5.72 0.3 2.31e-8 Systolic blood pressure; LIHC cis rs9814567 1.000 rs13071551 chr3:134310867 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.17 0.55 1.54e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg10295955 chr4:187884368 NA -0.97 -22.11 -0.77 6.56e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs2502731 1.000 rs2502731 chr9:130976557 A/G cg13642260 chr9:130955380 CIZ1 -0.52 -7.91 -0.39 3.67e-14 Attention deficit hyperactivity disorder; LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg16405210 chr4:1374714 KIAA1530 -0.91 -15.1 -0.63 8.06e-40 Longevity; LIHC trans rs7615952 0.611 rs7632305 chr3:125634767 C/T cg07211511 chr3:129823064 LOC729375 -0.81 -8.38 -0.41 1.35e-15 Blood pressure (smoking interaction); LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg14393609 chr7:65229607 NA 0.42 7.11 0.36 6.92e-12 Calcium levels; LIHC cis rs4746818 1.000 rs7909631 chr10:70918676 C/T cg11621586 chr10:70884670 VPS26A 0.87 14.21 0.61 2.47e-36 Left atrial antero-posterior diameter; LIHC cis rs11030122 0.632 rs4910596 chr11:4084604 A/G cg18678763 chr11:4115507 RRM1 -0.58 -8.55 -0.42 4.21e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs7336332 0.800 rs9805452 chr13:28047908 C/T cg22138327 chr13:27999177 GTF3A 0.43 6.48 0.33 3.2e-10 Weight; LIHC cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg08219700 chr8:58056026 NA 0.51 6.44 0.33 4.08e-10 Developmental language disorder (linguistic errors); LIHC cis rs9372498 0.536 rs9489407 chr6:118792337 A/T cg10217327 chr6:118973057 C6orf204 -0.62 -7.01 -0.35 1.29e-11 Diastolic blood pressure; LIHC cis rs3770081 1.000 rs2012798 chr2:86182756 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.74 -7.41 -0.37 1.01e-12 Facial emotion recognition (sad faces); LIHC cis rs950169 0.580 rs62021208 chr15:85196244 G/A cg03959625 chr15:84868606 LOC388152 0.44 6.3 0.32 8.99e-10 Schizophrenia; LIHC cis rs3770081 1.000 rs12624126 chr2:86342366 A/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.45 5.76 0.3 1.88e-8 Facial emotion recognition (sad faces); LIHC cis rs919433 1.000 rs112572902 chr2:198175179 G/C cg03934865 chr2:198174659 NA -0.6 -9.65 -0.46 1.16e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs2727020 0.576 rs1917321 chr11:49377760 A/C cg15704280 chr7:45808275 SEPT13 -0.6 -9.3 -0.45 1.73e-18 Coronary artery disease; LIHC cis rs2574704 0.781 rs2574722 chr3:11659877 T/C cg15876825 chr3:11651881 VGLL4 0.49 7.9 0.39 3.94e-14 Body mass index; LIHC cis rs6445797 0.632 rs2004199 chr3:56645866 A/G cg13792233 chr3:56591045 CCDC66 -0.39 -5.77 -0.3 1.81e-8 Gastritis; LIHC cis rs7639513 0.591 rs9849171 chr3:12622623 G/C cg23032965 chr3:12705835 RAF1 0.62 7.71 0.38 1.35e-13 Itch intensity from mosquito bite; LIHC cis rs9948 1.000 rs12172 chr2:97500852 C/G cg01990225 chr2:97406019 LMAN2L -0.65 -6.05 -0.31 3.75e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1144333 1.000 rs12410724 chr1:76459134 A/G cg10523679 chr1:76189770 ACADM 0.42 5.97 0.31 6.05e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs8072100 1.000 rs8065669 chr17:45724996 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.38 -6.06 -0.31 3.57e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4700695 0.925 rs12657113 chr5:65396959 A/C cg21114390 chr5:65439923 SFRS12 -0.5 -6.92 -0.35 2.24e-11 Facial morphology (factor 19); LIHC cis rs2933343 0.951 rs789220 chr3:128592135 A/G cg25356066 chr3:128598488 ACAD9 -0.53 -7.01 -0.35 1.25e-11 IgG glycosylation; LIHC cis rs651907 0.514 rs12636046 chr3:101434448 T/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.39 -0.33 5.47e-10 Colorectal cancer; LIHC cis rs8016982 0.633 rs9944085 chr14:81717620 A/T cg01989461 chr14:81687754 GTF2A1 -0.7 -14.33 -0.61 8.4e-37 Schizophrenia; LIHC cis rs11690935 0.550 rs11676438 chr2:172826668 G/A cg13550731 chr2:172543902 DYNC1I2 0.4 5.93 0.31 7.41e-9 Schizophrenia; LIHC cis rs28530618 0.603 rs11167173 chr20:31241612 A/T cg13636640 chr20:31349939 DNMT3B -0.43 -6.13 -0.31 2.38e-9 Birth weight; LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg21724239 chr8:58056113 NA 0.57 7.41 0.37 9.92e-13 Developmental language disorder (linguistic errors); LIHC cis rs826838 0.934 rs10875647 chr12:38856995 G/A cg13010199 chr12:38710504 ALG10B 0.61 7.5 0.38 5.64e-13 Heart rate; LIHC cis rs7937682 0.575 rs12808601 chr11:111776066 G/A cg09085632 chr11:111637200 PPP2R1B 0.92 13.82 0.6 8.34e-35 Primary sclerosing cholangitis; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg07161888 chr16:53537348 AKTIP -0.4 -6.08 -0.31 3.19e-9 Triglycerides; LIHC cis rs7131987 0.903 rs11050161 chr12:29420049 A/G cg00204748 chr12:29376779 FAR2 0.41 7.6 0.38 2.81e-13 QT interval; LIHC trans rs4815879 0.509 rs4815883 chr20:6040283 C/T cg23629183 chr3:97691400 MINA -0.63 -6.65 -0.34 1.18e-10 Preeclampsia; LIHC trans rs1814175 0.607 rs11493324 chr11:50011304 T/C cg15704280 chr7:45808275 SEPT13 -0.73 -13.02 -0.58 9.18e-32 Height; LIHC cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg16145915 chr7:1198662 ZFAND2A -0.37 -9.71 -0.47 7.35e-20 Longevity;Endometriosis; LIHC cis rs8044995 0.636 rs12596500 chr16:68299771 G/A cg09835421 chr16:68378352 PRMT7 -0.57 -5.92 -0.3 7.89e-9 Schizophrenia; LIHC cis rs7131987 0.650 rs4331146 chr12:29440083 G/T cg14222432 chr12:29376421 FAR2 0.36 6.97 0.35 1.64e-11 QT interval; LIHC cis rs13223928 0.666 rs9986825 chr7:3151177 C/T cg19214707 chr7:3157722 NA 0.36 6.59 0.34 1.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC trans rs208520 0.661 rs1100950 chr6:66827285 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -8.08 -0.4 1.12e-14 Exhaled nitric oxide output; LIHC cis rs9871864 0.868 rs62243505 chr3:20345616 T/C cg00235661 chr3:20228976 SGOL1 -0.3 -5.75 -0.3 1.96e-8 Behavioural disinhibition (generation interaction); LIHC cis rs2228479 0.850 rs11649162 chr16:89807131 C/A cg00800038 chr16:89945340 TCF25 -0.61 -8.94 -0.44 2.52e-17 Skin colour saturation; LIHC cis rs7249142 0.549 rs12609573 chr19:19297567 C/T cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B 0.41 6.76 0.34 6.09e-11 IgG glycosylation; LIHC cis rs208515 0.525 rs1351866 chr6:66696969 A/G cg07460842 chr6:66804631 NA 0.78 8.88 0.43 3.91e-17 Exhaled nitric oxide levels; LIHC cis rs6539288 0.500 rs11113116 chr12:107195929 C/A cg15890332 chr12:107067104 RFX4 0.26 6.09 0.31 3.08e-9 Total body bone mineral density; LIHC cis rs894734 0.567 rs7138907 chr12:54324576 C/T cg25024717 chr12:54324583 NA -0.38 -8.12 -0.4 8.31e-15 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9911578 0.900 rs4793593 chr17:56892699 C/G cg12560992 chr17:57184187 TRIM37 -0.96 -17.18 -0.68 4.1e-48 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25852545 chr3:113775465 KIAA1407;QTRTD1 -0.44 -6.15 -0.32 2.2e-9 Pancreatic cancer; LIHC cis rs9291683 0.595 rs3733585 chr4:10036339 A/G cg11266682 chr4:10021025 SLC2A9 0.35 7.45 0.37 7.45e-13 Bone mineral density; LIHC cis rs600806 0.850 rs10858091 chr1:109935578 T/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC trans rs5756813 0.727 rs4820303 chr22:38134166 G/A cg19894588 chr14:64061835 NA -0.59 -8.01 -0.4 1.82e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7089973 0.668 rs7898347 chr10:116644324 G/A cg03647239 chr10:116582469 FAM160B1 0.46 6.58 0.34 1.77e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4407350 0.721 rs131156 chr22:44891370 T/C cg26276947 chr22:44892394 LDOC1L 0.31 6.01 0.31 4.71e-9 Intelligence (multi-trait analysis); LIHC cis rs1577917 1.000 rs13196930 chr6:86652245 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.45 -7.13 -0.36 6.16e-12 Response to antipsychotic treatment; LIHC cis rs1165668 1.000 rs1866071 chr12:104310638 T/C cg21863207 chr12:104234989 NT5DC3 0.4 6.39 0.33 5.27e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs7116495 0.609 rs501308 chr11:71581325 C/G cg10381502 chr11:71823885 C11orf51 0.96 8.13 0.4 7.71e-15 Severe influenza A (H1N1) infection; LIHC cis rs11255291 0.668 rs4749169 chr10:7737661 G/C cg00997801 chr10:7671259 ITIH5 0.37 6.01 0.31 4.87e-9 Ovarian reserve; LIHC cis rs68092024 0.704 rs793487 chr3:99495422 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.44 6.21 0.32 1.54e-9 Cleft lip with or without cleft palate; LIHC cis rs7551222 0.646 rs6594015 chr1:204461622 C/T cg20240347 chr1:204465584 NA -0.33 -6.86 -0.35 3.25e-11 Schizophrenia; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg15920131 chr12:57601886 LRP1 0.4 6.71 0.34 8.15e-11 Alopecia areata; LIHC cis rs77633900 0.772 rs157761 chr15:76796078 C/A cg21673338 chr15:77095150 SCAPER -0.51 -5.84 -0.3 1.21e-8 Non-glioblastoma glioma;Glioma; LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.83 0.39 6.04e-14 Height; LIHC cis rs262150 0.837 rs2657404 chr7:158783155 C/T cg19418458 chr7:158789849 NA -0.39 -6.66 -0.34 1.07e-10 Facial morphology (factor 20); LIHC cis rs12594515 1.000 rs6493176 chr15:45990026 A/G cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC cis rs9467773 0.869 rs1796520 chr6:26410800 C/T cg09904177 chr6:26538194 HMGN4 -0.49 -9.04 -0.44 1.22e-17 Intelligence (multi-trait analysis); LIHC cis rs1784581 0.928 rs1789995 chr6:162396518 C/T cg17173639 chr6:162384350 PARK2 -0.71 -15.18 -0.63 3.67e-40 Itch intensity from mosquito bite; LIHC cis rs875971 0.862 rs3893216 chr7:65790707 G/C cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC trans rs4650994 0.525 rs4993304 chr1:178535144 A/G cg05059571 chr16:84539110 KIAA1609 -0.44 -7.35 -0.37 1.46e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs4819052 0.808 rs11909411 chr21:46676556 A/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.91 0.39 3.69e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9486715 1.000 rs9486715 chr6:97059769 A/C cg06623918 chr6:96969491 KIAA0776 -0.86 -14.39 -0.61 4.81e-37 Headache; LIHC trans rs1945213 0.694 rs67394518 chr11:55855303 G/A cg15704280 chr7:45808275 SEPT13 0.6 7.45 0.37 7.6e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 11.09 0.51 1.23e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1443512 0.796 rs1822437 chr12:54340077 A/G cg17410650 chr12:54324560 NA 0.38 6.91 0.35 2.43e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs4975709 0.569 rs1684965 chr5:1865248 A/G cg14773178 chr5:1868261 NA 0.26 7.1 0.36 7.33e-12 Cardiovascular disease risk factors; LIHC cis rs7772486 0.754 rs702323 chr6:146008274 A/G cg13319975 chr6:146136371 FBXO30 0.36 5.76 0.3 1.9e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs807029 0.533 rs2863095 chr10:102746503 C/T cg27255678 chr10:102756921 LZTS2 0.52 7.41 0.37 9.92e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7918232 0.941 rs1753413 chr10:27397112 T/C cg14442939 chr10:27389572 ANKRD26 0.74 7.08 0.36 8.34e-12 Breast cancer; LIHC cis rs4919087 0.892 rs10882881 chr10:99010067 T/A cg25902810 chr10:99078978 FRAT1 0.62 8.97 0.44 1.99e-17 Monocyte count; LIHC cis rs10078 1.000 rs10078 chr5:438102 G/T cg26072250 chr5:443457 EXOC3;C5orf55 0.54 7.15 0.36 5.29e-12 Fat distribution (HIV); LIHC cis rs72638986 1.000 rs6474359 chr8:41549194 A/G cg22352078 chr8:41424982 NA -0.36 -5.83 -0.3 1.27e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg05185784 chr16:90016020 DEF8 -0.45 -5.91 -0.3 8.49e-9 Skin colour saturation; LIHC cis rs7772486 0.846 rs2748496 chr6:146321829 T/A cg23711669 chr6:146136114 FBXO30 0.6 10.46 0.49 2.11e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs9311474 0.607 rs34005367 chr3:52558904 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.44 5.85 0.3 1.18e-8 Electroencephalogram traits; LIHC trans rs11088226 0.681 rs2833897 chr21:33931792 T/C cg09050820 chr6:167586206 TCP10L2 0.85 13.53 0.59 1.05e-33 Gastritis; LIHC trans rs6489882 0.902 rs4767040 chr12:113374017 C/G cg10175203 chr3:128143634 NA 0.38 6.17 0.32 1.96e-9 Chronic lymphocytic leukemia; LIHC trans rs35110281 0.811 rs7275705 chr21:45056453 G/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.17 0.32 1.92e-9 Mean corpuscular volume; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06010356 chr16:74847234 NA 0.42 6.09 0.31 3.11e-9 Lung function (FEV1/FVC); LIHC cis rs244293 0.929 rs181728 chr17:53185803 T/C cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs10751667 0.666 rs7944815 chr11:959776 C/T ch.11.42038R chr11:967971 AP2A2 0.56 10.08 0.48 4.14e-21 Alzheimer's disease (late onset); LIHC cis rs7587476 0.784 rs13032278 chr2:215698034 G/A cg04004882 chr2:215674386 BARD1 0.57 7.81 0.39 6.92e-14 Neuroblastoma; LIHC cis rs7617480 0.558 rs12715430 chr3:48942855 A/C cg07636037 chr3:49044803 WDR6 0.76 9.3 0.45 1.66e-18 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg00280220 chr17:61926910 NA 0.44 7.07 0.36 8.7e-12 Prudent dietary pattern; LIHC cis rs2191566 0.960 rs8105571 chr19:44510341 C/T cg18700516 chr19:44507157 ZNF230 -0.35 -5.79 -0.3 1.62e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs763121 0.889 rs6001209 chr22:39121252 C/T cg06022373 chr22:39101656 GTPBP1 -0.58 -9.67 -0.46 9.95e-20 Menopause (age at onset); LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg07167872 chr1:205819463 PM20D1 0.71 10.31 0.49 7.13e-22 Menarche (age at onset); LIHC trans rs2359714 0.935 rs1344010 chr1:118802310 A/G cg19861078 chr7:7936962 NA -0.31 -6.18 -0.32 1.8e-9 Breast size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25951580 chr19:58962937 ZNF324B -0.48 -6.32 -0.32 8.29e-10 Pancreatic cancer; LIHC cis rs875971 0.545 rs316328 chr7:65608838 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -7.01 -0.35 1.32e-11 Aortic root size; LIHC cis rs3806933 0.522 rs13179305 chr5:110444474 G/A cg04022379 chr5:110408740 TSLP 0.56 9.12 0.44 6.71e-18 Eosinophilic esophagitis; LIHC cis rs904251 0.797 rs1757181 chr6:37485728 A/G cg25019722 chr6:37503610 NA 0.37 6.35 0.32 6.94e-10 Cognitive performance; LIHC cis rs7940866 0.845 rs1433976 chr11:130875123 C/T cg12179176 chr11:130786555 SNX19 -0.49 -7.03 -0.36 1.1e-11 Schizophrenia; LIHC trans rs11098499 0.691 rs2136911 chr4:120265859 G/A cg25214090 chr10:38739885 LOC399744 0.44 7.16 0.36 5.01e-12 Corneal astigmatism; LIHC cis rs12479064 0.724 rs11885942 chr2:100004165 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.52 -7.17 -0.36 4.76e-12 Chronic sinus infection; LIHC cis rs7106204 0.514 rs12282611 chr11:24271352 A/C ch.11.24196551F chr11:24239977 NA 0.73 8.86 0.43 4.29e-17 Response to Homoharringtonine (cytotoxicity); LIHC cis rs9911578 0.967 rs9907940 chr17:56663842 A/G cg12560992 chr17:57184187 TRIM37 0.97 17.74 0.69 2.19e-50 Intelligence (multi-trait analysis); LIHC cis rs12824058 0.831 rs11608406 chr12:130805866 G/C cg24229701 chr12:130821962 PIWIL1 0.43 6.24 0.32 1.27e-9 Menopause (age at onset); LIHC cis rs9303280 0.742 rs11557466 chr17:38024626 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.84 0.3 1.19e-8 Self-reported allergy; LIHC cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg00166722 chr3:10149974 C3orf24 0.53 6.15 0.32 2.11e-9 Alzheimer's disease; LIHC cis rs9300255 0.602 rs2851438 chr12:123643689 T/C cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg04234412 chr22:24373322 LOC391322 -0.71 -10.58 -0.5 8.19e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7772486 0.754 rs9390356 chr6:146118983 A/T cg13319975 chr6:146136371 FBXO30 0.39 6.36 0.33 6.6e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2286503 0.839 rs2240728 chr7:22852499 C/T cg11367502 chr7:22862612 TOMM7 0.43 7.16 0.36 4.96e-12 Fibrinogen; LIHC trans rs7618501 0.633 rs2526751 chr3:50064867 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.58 -9.57 -0.46 2.24e-19 Intelligence (multi-trait analysis); LIHC cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.85 0.35 3.35e-11 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg21724239 chr8:58056113 NA 0.57 7.5 0.38 5.53e-13 Developmental language disorder (linguistic errors); LIHC cis rs28374715 0.532 rs316606 chr15:41772202 A/C cg18705301 chr15:41695430 NDUFAF1 -1.25 -17.87 -0.69 6.28e-51 Ulcerative colitis; LIHC cis rs1775715 0.870 rs1755072 chr10:32266642 A/G cg14930904 chr10:32216787 ARHGAP12 -0.39 -7.03 -0.36 1.12e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs11758351 0.925 rs78932312 chr6:26194869 A/G cg16070018 chr6:26224392 HIST1H3E 0.57 6.81 0.35 4.47e-11 Gout;Renal underexcretion gout; LIHC cis rs4407350 0.756 rs3827401 chr22:44890618 A/G cg11695653 chr22:44894386 LDOC1L -0.38 -6.45 -0.33 3.84e-10 Intelligence (multi-trait analysis); LIHC cis rs4843747 0.671 rs28465438 chr16:88103714 G/A cg06050784 chr16:88016603 BANP 0.38 6.97 0.35 1.67e-11 Menopause (age at onset); LIHC cis rs7618915 0.547 rs11719685 chr3:52676065 C/T cg10802521 chr3:52805072 NEK4 -0.42 -6.67 -0.34 1.05e-10 Bipolar disorder; LIHC cis rs17685 0.753 rs11972240 chr7:75694079 A/C cg04610667 chr7:75704037 NA -0.34 -6.08 -0.31 3.13e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17528700 chr6:99968879 NA -0.47 -6.59 -0.34 1.7e-10 Pancreatic cancer; LIHC cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg10862848 chr6:42927986 GNMT -0.25 -5.79 -0.3 1.55e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs240764 0.817 rs12214151 chr6:101159516 G/T cg09795085 chr6:101329169 ASCC3 -0.52 -7.15 -0.36 5.42e-12 Neuroticism; LIHC cis rs7903847 0.642 rs6584127 chr10:99142948 A/C cg08345082 chr10:99160200 RRP12 -0.38 -6.35 -0.32 6.66e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9814567 0.964 rs9815983 chr3:134222507 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.29 -0.55 5.21e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6500602 0.647 rs4786501 chr16:4536165 G/T cg08345575 chr16:4524283 NMRAL1;HMOX2 -0.41 -5.75 -0.3 1.94e-8 Schizophrenia; LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg17178900 chr1:205818956 PM20D1 0.65 9.82 0.47 3.35e-20 Menarche (age at onset); LIHC trans rs9914544 0.545 rs12600851 chr17:18767518 T/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.56 -0.33 2.02e-10 Educational attainment (years of education); LIHC cis rs6062302 0.549 rs4809586 chr20:62249402 C/T cg09650180 chr20:62225654 GMEB2 -0.38 -6.05 -0.31 3.87e-9 Glioblastoma; LIHC cis rs2242116 1.000 rs1138518 chr3:46944274 T/C cg23352942 chr3:46931381 PTH1R -0.25 -6.12 -0.31 2.57e-9 Birth weight; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.15 -0.32 2.18e-9 Total body bone mineral density; LIHC cis rs4819052 0.851 rs2838845 chr21:46670812 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.32 0.37 1.81e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.71 11.5 0.53 4.26e-26 Prudent dietary pattern; LIHC cis rs11098499 0.863 rs12498539 chr4:120468370 C/T cg09307838 chr4:120376055 NA 0.75 11.59 0.53 1.95e-26 Corneal astigmatism; LIHC trans rs2727020 0.729 rs2204366 chr11:49349367 A/C cg03929089 chr4:120376271 NA 0.82 14.46 0.62 2.56e-37 Coronary artery disease; LIHC cis rs4843747 0.671 rs9933794 chr16:88116981 T/C cg06050784 chr16:88016603 BANP 0.38 6.66 0.34 1.09e-10 Menopause (age at onset); LIHC cis rs6977660 1.000 rs7779902 chr7:19803491 G/A cg07541023 chr7:19748670 TWISTNB 0.39 6.18 0.32 1.82e-9 Thyroid stimulating hormone; LIHC cis rs2851682 1.000 rs2845574 chr11:61601872 C/T cg27386326 chr11:61587980 NA 0.59 8.8 0.43 7e-17 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs4555082 1.000 rs4277291 chr14:105759009 A/G cg13114125 chr14:105738426 BRF1 -0.7 -9.36 -0.45 1.08e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs7552404 0.961 rs448710 chr1:76116554 T/C cg10523679 chr1:76189770 ACADM -0.66 -9.21 -0.45 3.36e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs17685 0.712 rs11764119 chr7:75812358 T/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.37 -6.05 -0.31 3.91e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7100689 0.646 rs4357632 chr10:82131783 C/T cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs3768617 0.510 rs1413387 chr1:183096774 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.63 0.5 5.27e-23 Fuchs's corneal dystrophy; LIHC cis rs870825 0.616 rs6552810 chr4:185644143 G/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.83 0.39 6e-14 Prudent dietary pattern; LIHC cis rs6684514 1.000 rs10908496 chr1:156264000 G/A cg16558208 chr1:156270281 VHLL 0.54 10.19 0.48 1.79e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs11868206 1 rs11868206 chr17:33959247 G/A cg20932281 chr17:33905541 PEX12 0.57 7.4 0.37 1.08e-12 Mean platelet volume; LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.826 rs12511640 chr4:120251248 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.29 0.41 2.61e-15 Corneal astigmatism; LIHC trans rs926340 0.777 rs5753284 chr22:31116394 A/G cg09032630 chr6:27831956 HIST1H2AL 0.35 6.48 0.33 3.13e-10 Colorectal cancer; LIHC cis rs1568889 0.887 rs2062269 chr11:28116537 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.0 0.6 1.59e-35 Bipolar disorder; LIHC cis rs818427 0.896 rs818429 chr5:112220534 T/C cg07820702 chr5:112228657 REEP5 -0.39 -6.14 -0.32 2.23e-9 Total body bone mineral density; LIHC cis rs1023500 0.573 rs4822088 chr22:42470589 G/C cg15557168 chr22:42548783 NA -0.43 -6.86 -0.35 3.22e-11 Schizophrenia; LIHC cis rs921968 0.541 rs3755042 chr2:219317248 T/C cg02985541 chr2:219472218 PLCD4 -0.44 -7.18 -0.36 4.25e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs4319547 0.695 rs7969429 chr12:122875606 A/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.19 -0.36 3.98e-12 Body mass index; LIHC cis rs4450131 1.000 rs10901799 chr10:126348274 A/G cg20435097 chr10:126320824 FAM53B -0.5 -9.16 -0.44 4.73e-18 White blood cell count (basophil); LIHC cis rs6860806 0.507 rs272868 chr5:131680751 C/G cg24060327 chr5:131705240 SLC22A5 -0.78 -12.2 -0.55 1.16e-28 Breast cancer; LIHC cis rs8072100 0.701 rs10163469 chr17:45687767 G/A cg08085267 chr17:45401833 C17orf57 0.41 6.18 0.32 1.82e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7772486 0.764 rs7762562 chr6:146158994 T/C cg23711669 chr6:146136114 FBXO30 0.65 11.72 0.54 6.98e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs2108622 0.727 rs76984410 chr19:15982700 C/T cg13772218 chr19:15982569 NA 0.37 7.78 0.39 8.7e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs4654899 0.965 rs10753513 chr1:21492168 T/C cg08539965 chr1:21396338 EIF4G3 -0.32 -5.73 -0.3 2.26e-8 Superior frontal gyrus grey matter volume; LIHC cis rs7927592 0.913 rs11228262 chr11:68274907 G/T cg20283391 chr11:68216788 NA -0.52 -7.75 -0.39 1.05e-13 Total body bone mineral density; LIHC cis rs637571 0.510 rs3892696 chr11:65582341 G/C cg04055107 chr11:65626734 MUS81;CFL1 -0.43 -6.23 -0.32 1.4e-9 Eosinophil percentage of white cells; LIHC cis rs11122272 0.735 rs2491405 chr1:231513431 C/A cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg27478167 chr7:817139 HEATR2 -0.51 -6.81 -0.35 4.4e-11 Cerebrospinal P-tau181p levels; LIHC cis rs7267979 1.000 rs2258617 chr20:25274318 C/T cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC trans rs11722228 0.522 rs62286604 chr4:10131161 A/G cg26043149 chr18:55253948 FECH 0.95 14.57 0.62 9.88e-38 Gout;Urate levels;Serum uric acid levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27658640 chr17:4843839 RNF167;SLC25A11 0.43 6.82 0.35 4.24e-11 Cognitive function; LIHC cis rs7072216 0.690 rs113195335 chr10:100175532 A/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.09e-10 Metabolite levels; LIHC cis rs12824058 0.549 rs4759453 chr12:130824565 C/G cg24229701 chr12:130821962 PIWIL1 0.43 6.63 0.34 1.35e-10 Menopause (age at onset); LIHC cis rs7223966 1.000 rs8075273 chr17:61728881 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 6.33 0.32 7.6e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs875971 0.660 rs62465434 chr7:66005152 A/C cg11764359 chr7:65958608 NA 0.72 11.04 0.51 1.9e-24 Aortic root size; LIHC cis rs55823223 0.564 rs936391 chr17:73847799 A/G cg10935138 chr17:73851978 WBP2 -0.65 -9.16 -0.44 4.84e-18 Psoriasis; LIHC cis rs7224685 0.569 rs965515 chr17:4038149 G/A cg09695851 chr17:3907499 NA 0.62 7.16 0.36 5.04e-12 Type 2 diabetes; LIHC cis rs7107174 0.892 rs2512529 chr11:77977351 C/T cg02023728 chr11:77925099 USP35 0.5 9.52 0.46 3.35e-19 Testicular germ cell tumor; LIHC cis rs67981189 0.593 rs2240531 chr14:71553606 A/G cg15816911 chr14:71606274 NA 0.44 6.99 0.35 1.45e-11 Schizophrenia; LIHC cis rs9911578 1.000 rs2643119 chr17:56827760 G/T cg12560992 chr17:57184187 TRIM37 0.96 17.17 0.68 4.27e-48 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.528 rs7573555 chr2:136694905 C/T cg25344623 chr2:136566232 LCT 0.35 5.73 0.3 2.19e-8 Corneal structure; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg04219446 chr17:73629082 RECQL5;LOC643008 -0.43 -6.13 -0.31 2.47e-9 Triglycerides; LIHC cis rs9993613 1.000 rs9993613 chr4:73476014 T/G cg15102770 chr4:73434591 ADAMTS3 -0.37 -5.75 -0.3 2.01e-8 Hip circumference adjusted for BMI;Height; LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg19635926 chr16:89946313 TCF25 0.54 6.9 0.35 2.49e-11 Skin colour saturation; LIHC trans rs11724903 0.935 rs7698341 chr4:183211749 G/A cg16239906 chr20:35724590 RBL1 -0.66 -6.22 -0.32 1.46e-9 Smoking initiation; LIHC cis rs7572733 0.534 rs7604700 chr2:198718630 A/G cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs10861342 1.000 rs10861358 chr12:105559563 G/A cg23923672 chr12:105501055 KIAA1033 0.57 7.43 0.37 8.65e-13 IgG glycosylation; LIHC cis rs68170813 0.523 rs79619227 chr7:107025335 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.74 -0.3 2.1e-8 Coronary artery disease; LIHC trans rs1814175 0.645 rs10444311 chr11:49986906 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs7903847 0.642 rs10786344 chr10:99165975 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.79 -0.34 5.08e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.44 6.09 0.31 3.04e-9 Mean platelet volume; LIHC cis rs1707322 1.000 rs10890355 chr1:46317348 G/A cg03146154 chr1:46216737 IPP 0.47 7.64 0.38 2.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6831352 0.703 rs3133152 chr4:100031721 C/G cg12011299 chr4:100065546 ADH4 0.56 9.87 0.47 2.2e-20 Alcohol dependence; LIHC cis rs1707322 0.752 rs6658700 chr1:46160260 C/T cg03146154 chr1:46216737 IPP 0.58 9.58 0.46 2.05e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1198872 0.503 rs1627163 chr2:10954844 A/G cg15705551 chr2:10952987 PDIA6 0.47 6.49 0.33 3.1e-10 Cardiac Troponin-T levels; LIHC cis rs875971 0.862 rs2088655 chr7:65795711 T/C cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg12903224 chr12:29470962 FAR2 -0.38 -6.01 -0.31 4.86e-9 QT interval; LIHC cis rs644148 0.872 rs2686780 chr19:44974126 G/C cg15540054 chr19:45004280 ZNF180 -0.77 -10.71 -0.5 2.88e-23 Personality dimensions; LIHC cis rs12971120 0.947 rs3764509 chr18:72167124 C/G cg26446133 chr18:72167187 CNDP2 -0.79 -15.85 -0.65 8.51e-43 Refractive error; LIHC cis rs7520050 0.966 rs4545281 chr1:46360054 C/T cg03146154 chr1:46216737 IPP -0.38 -6.3 -0.32 9.25e-10 Red blood cell count;Reticulocyte count; LIHC cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg13395646 chr4:1353034 KIAA1530 0.42 6.71 0.34 7.99e-11 Obesity-related traits; LIHC cis rs9596863 0.898 rs9568911 chr13:54338082 A/G ch.13.53330881F chr13:54432880 NA 0.44 6.1 0.31 2.92e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9640161 0.750 rs59211922 chr7:150023790 T/G cg17279839 chr7:150038598 RARRES2 0.5 10.59 0.5 7.42e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs875971 0.522 rs781144 chr7:65440344 C/G cg14393609 chr7:65229607 NA 0.43 6.26 0.32 1.14e-9 Aortic root size; LIHC cis rs17286411 0.669 rs4788814 chr16:71634604 A/T cg06353428 chr16:71660113 MARVELD3 -0.41 -6.01 -0.31 4.8e-9 Blood protein levels; LIHC cis rs17401966 1.000 rs2229687 chr1:10473196 C/T cg19773385 chr1:10388646 KIF1B -0.39 -6.35 -0.32 6.92e-10 Hepatocellular carcinoma; LIHC cis rs6088580 0.524 rs6087612 chr20:33230822 T/G cg07148914 chr20:33460835 GGT7 -0.49 -7.02 -0.36 1.18e-11 Glomerular filtration rate (creatinine); LIHC cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg00166722 chr3:10149974 C3orf24 0.48 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC trans rs1005277 0.579 rs2472181 chr10:38386764 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg05614176 chr13:113242512 TUBGCP3 -0.46 -6.14 -0.32 2.33e-9 Alcohol dependence; LIHC cis rs7208859 0.673 rs73277964 chr17:29179201 A/T cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1005277 0.579 rs1780146 chr10:38517874 C/A cg03665457 chr10:38645376 HSD17B7P2 -0.45 -6.49 -0.33 3.09e-10 Extrinsic epigenetic age acceleration; LIHC cis rs4819052 0.851 rs28622522 chr21:46676599 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.91 0.39 3.71e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9911578 0.967 rs3826353 chr17:57075299 C/T cg05425664 chr17:57184151 TRIM37 -0.58 -8.79 -0.43 7.38e-17 Intelligence (multi-trait analysis); LIHC cis rs4911259 0.593 rs6058924 chr20:31464467 G/A cg13636640 chr20:31349939 DNMT3B -0.61 -10.78 -0.5 1.56e-23 Inflammatory bowel disease; LIHC cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg07424592 chr7:64974309 NA 0.78 9.0 0.44 1.64e-17 Diabetic kidney disease; LIHC cis rs876084 0.505 rs7827219 chr8:121130164 G/A cg06265175 chr8:121136014 COL14A1 0.42 6.68 0.34 9.71e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs600806 0.714 rs12137189 chr1:110013215 A/G cg11161837 chr1:110010384 SYPL2 0.45 6.28 0.32 1.04e-9 Intelligence (multi-trait analysis); LIHC cis rs8177253 1.000 rs8177252 chr3:133480174 C/A cg12373951 chr3:133503437 NA 0.69 12.44 0.56 1.41e-29 Iron status biomarkers; LIHC cis rs4638749 0.677 rs10174695 chr2:108842164 G/A cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs7937682 0.663 rs3867466 chr11:111668256 A/C cg09085632 chr11:111637200 PPP2R1B 0.96 14.3 0.61 1.08e-36 Primary sclerosing cholangitis; LIHC cis rs35110281 0.807 rs9984002 chr21:45061501 T/C cg21573476 chr21:45109991 RRP1B -0.57 -10.89 -0.51 6.8e-24 Mean corpuscular volume; LIHC cis rs6912958 0.703 rs9359748 chr6:88095500 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.59 11.1 0.51 1.14e-24 Monocyte percentage of white cells; LIHC cis rs910316 0.967 rs2268619 chr14:75640354 C/G cg08847533 chr14:75593920 NEK9 -0.89 -17.95 -0.7 3.03e-51 Height; LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC cis rs17685 0.712 rs28456330 chr7:75810542 A/G cg16684958 chr7:75615977 POR 0.49 8.35 0.41 1.76e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9916302 0.904 rs8077104 chr17:37530510 A/G cg07936489 chr17:37558343 FBXL20 0.85 13.77 0.6 1.22e-34 Glomerular filtration rate (creatinine); LIHC trans rs2727020 0.656 rs7925524 chr11:49437542 G/A cg15704280 chr7:45808275 SEPT13 -0.79 -12.65 -0.56 2.47e-30 Coronary artery disease; LIHC cis rs8141529 0.509 rs5762864 chr22:29253364 T/C cg15103426 chr22:29168792 CCDC117 0.66 10.36 0.49 4.77e-22 Lymphocyte counts; LIHC trans rs12752401 0.867 rs34777937 chr1:103036317 C/A cg24921808 chr19:740313 PALM 0.49 6.42 0.33 4.6e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs9814567 1.000 rs4368544 chr3:134300014 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.88 0.3 9.95e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6088813 1.000 rs6060401 chr20:34005214 C/T cg14752227 chr20:34000481 UQCC -0.4 -5.8 -0.3 1.54e-8 Height; LIHC cis rs6714710 0.603 rs6746768 chr2:98466647 C/T cg26665480 chr2:98280029 ACTR1B 0.44 6.19 0.32 1.76e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs7249142 0.561 rs4808185 chr19:19296217 A/G cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.38 -6.38 -0.33 5.63e-10 IgG glycosylation; LIHC cis rs1568889 1.000 rs66857704 chr11:28212346 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.02 0.35 1.22e-11 Bipolar disorder; LIHC cis rs17401966 0.838 rs1556916 chr1:10403482 G/A cg19773385 chr1:10388646 KIF1B -0.4 -6.97 -0.35 1.67e-11 Hepatocellular carcinoma; LIHC cis rs875971 0.660 rs801190 chr7:66033033 C/T cg18876405 chr7:65276391 NA -0.44 -7.7 -0.38 1.44e-13 Aortic root size; LIHC cis rs3768617 0.510 rs3768622 chr1:183090011 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 5.05e-23 Fuchs's corneal dystrophy; LIHC cis rs35883536 0.647 rs12046413 chr1:101047430 T/C cg14515779 chr1:101123966 NA 0.5 6.9 0.35 2.49e-11 Monocyte count; LIHC cis rs2760061 0.626 rs2527614 chr1:228126470 A/G cg02753203 chr1:228287806 NA -0.47 -7.44 -0.37 7.96e-13 Diastolic blood pressure; LIHC cis rs7216064 1.000 rs12451511 chr17:65874861 T/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs35110281 0.744 rs162373 chr21:44927107 C/A cg01579765 chr21:45077557 HSF2BP 0.32 6.05 0.31 3.81e-9 Mean corpuscular volume; LIHC cis rs7412746 0.658 rs12068264 chr1:150727329 C/T cg15448220 chr1:150897856 SETDB1 0.44 6.74 0.34 6.63e-11 Melanoma; LIHC cis rs9916302 0.904 rs11078915 chr17:37715426 T/C cg00129232 chr17:37814104 STARD3 -0.41 -6.52 -0.33 2.47e-10 Glomerular filtration rate (creatinine); LIHC trans rs1814175 0.645 rs11040699 chr11:50023798 C/G cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs10426930 0.816 rs858414 chr19:5055196 T/C cg18473234 chr19:5097819 KDM4B -0.54 -6.87 -0.35 3.14e-11 Monocyte percentage of white cells; LIHC cis rs3823572 0.542 rs28654576 chr7:133624445 A/G cg03336402 chr7:133662267 EXOC4 0.51 6.4 0.33 5.2400000000000005e-10 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg23758822 chr17:41437982 NA 0.93 17.45 0.69 3.28e-49 Menopause (age at onset); LIHC cis rs1008375 1.000 rs7697889 chr4:17617961 G/T cg16339924 chr4:17578868 LAP3 0.44 6.13 0.31 2.42e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9980664 1.000 rs2834204 chr21:34737098 T/C cg04842828 chr21:34696676 IFNAR1 0.46 6.15 0.32 2.12e-9 Cognitive decline (age-related); LIHC cis rs7187994 0.848 rs12933308 chr16:84770973 A/G cg07647771 chr16:84786436 USP10 -0.34 -6.3 -0.32 9.21e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs1461503 0.934 rs7107560 chr11:122845380 T/C cg14473756 chr11:122847823 NA -0.35 -6.22 -0.32 1.42e-9 Menarche (age at onset); LIHC cis rs10508774 0.925 rs11008947 chr10:32765415 G/A cg01819863 chr10:32635814 EPC1 0.65 6.08 0.31 3.28e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1401454 1.000 rs2351958 chr11:16248020 C/A cg02656851 chr11:16430247 SOX6 -0.33 -6.27 -0.32 1.08e-9 Blood pressure; LIHC cis rs9303401 0.659 rs34468504 chr17:56648277 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs9914988 0.943 rs2242345 chr17:27185827 C/T cg20469991 chr17:27169893 C17orf63 0.48 5.78 0.3 1.71e-8 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs6952808 1.000 rs12699404 chr7:1894022 A/T cg02951883 chr7:2050386 MAD1L1 -0.59 -8.67 -0.42 1.73e-16 Bipolar disorder and schizophrenia; LIHC cis rs473651 0.935 rs520765 chr2:239354712 C/T cg18131467 chr2:239335373 ASB1 1.09 20.65 0.74 4.29e-62 Multiple system atrophy; LIHC cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg18230493 chr5:56204884 C5orf35 0.42 5.82 0.3 1.36e-8 Initial pursuit acceleration; LIHC cis rs1395 0.744 rs57881048 chr2:27474165 T/C cg22903471 chr2:27725779 GCKR -0.41 -6.16 -0.32 2e-9 Blood metabolite levels; LIHC cis rs992157 0.965 rs13419763 chr2:219134950 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.8 12.87 0.57 3.46e-31 Colorectal cancer; LIHC cis rs10861342 0.786 rs11112386 chr12:105538758 A/G cg23923672 chr12:105501055 KIAA1033 0.64 7.66 0.38 1.98e-13 IgG glycosylation; LIHC cis rs6882046 0.513 rs34316 chr5:88015545 A/C cg22951263 chr5:87985283 NA -0.36 -6.28 -0.32 1.05e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs13064411 0.696 rs7631082 chr3:113208913 C/G cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs6748734 1.000 rs6751693 chr2:241837332 T/C cg08694578 chr2:241835147 C2orf54 -0.51 -6.91 -0.35 2.31e-11 Urinary metabolites; LIHC cis rs7918232 0.941 rs6482598 chr10:27426375 T/C cg14240646 chr10:27532245 ACBD5 -0.66 -6.29 -0.32 9.9e-10 Breast cancer; LIHC cis rs372883 0.648 rs368322 chr21:30717151 C/T cg24692254 chr21:30365293 RNF160 -0.5 -6.29 -0.32 9.94e-10 Pancreatic cancer; LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.67 -0.34 1.05e-10 Total body bone mineral density; LIHC cis rs1046896 0.553 rs9893885 chr17:80837107 C/T cg02398342 chr17:80708632 TBCD;FN3K 0.41 6.24 0.32 1.28e-9 Glycated hemoglobin levels; LIHC cis rs1008375 1.000 rs56308330 chr4:17643050 G/A cg16339924 chr4:17578868 LAP3 0.44 6.13 0.31 2.38e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6570726 0.791 rs9373463 chr6:145894762 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.37 -0.33 6.08e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7129727 1 rs7129727 chr11:57484660 G/A cg19752551 chr11:57585705 CTNND1 -0.51 -7.25 -0.37 2.72e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs7116495 0.609 rs4477459 chr11:71720616 T/C cg26138937 chr11:71823887 C11orf51 -1.32 -10.9 -0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs2625529 0.761 rs4776582 chr15:72207520 A/T cg16672083 chr15:72433130 SENP8 -0.31 -5.8 -0.3 1.48e-8 Red blood cell count; LIHC cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg21782813 chr7:2030301 MAD1L1 0.41 6.8 0.34 4.82e-11 Bipolar disorder and schizophrenia; LIHC cis rs295140 0.507 rs4673814 chr2:201108133 G/A cg23649088 chr2:200775458 C2orf69 -0.51 -7.02 -0.35 1.21e-11 QT interval; LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg00280220 chr17:61926910 NA 0.42 6.79 0.34 4.88e-11 Prudent dietary pattern; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13462232 chr20:17551166 DSTN 0.49 6.16 0.32 2.09e-9 Hepatitis; LIHC cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg11764359 chr7:65958608 NA 0.58 5.98 0.31 5.58e-9 Diabetic kidney disease; LIHC cis rs2274273 0.623 rs1187877 chr14:55495161 T/C cg01864836 chr14:55583639 NA 0.36 6.07 0.31 3.31e-9 Protein biomarker; LIHC cis rs780094 0.585 rs3739095 chr2:27556721 C/T cg27432699 chr2:27873401 GPN1 -0.41 -5.89 -0.3 9.07e-9 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs11958404 0.932 rs72816547 chr5:157417820 G/T cg05962755 chr5:157440814 NA 1.05 11.06 0.51 1.64e-24 IgG glycosylation; LIHC cis rs8060686 0.545 rs10500543 chr16:68281311 T/C cg09835421 chr16:68378352 PRMT7 -0.54 -6.3 -0.32 9.14e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs8017423 0.904 rs7147212 chr14:90697809 A/C cg04374321 chr14:90722782 PSMC1 0.74 14.16 0.61 3.76e-36 Mortality in heart failure; LIHC cis rs11958404 0.932 rs61478293 chr5:157426299 G/A cg05962755 chr5:157440814 NA 0.92 10.56 0.5 9.87e-23 IgG glycosylation; LIHC cis rs801193 0.569 rs6951302 chr7:66132512 T/C cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs4713118 0.955 rs34752872 chr6:27683244 A/T cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC cis rs7208859 0.623 rs56095789 chr17:29060170 A/G cg13385521 chr17:29058706 SUZ12P 0.84 8.37 0.41 1.49e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3736485 0.934 rs4775956 chr15:51882638 G/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01941274 chr14:50234650 KLHDC2 0.44 6.52 0.33 2.53e-10 Lung function (FEV1/FVC); LIHC cis rs8180040 0.690 rs7640397 chr3:46989828 C/T cg27129171 chr3:47204927 SETD2 0.61 10.48 0.49 1.84e-22 Colorectal cancer; LIHC cis rs787274 0.543 rs62576453 chr9:115629921 C/T cg13803584 chr9:115635662 SNX30 -0.63 -8.97 -0.44 1.92e-17 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs4718428 0.705 rs4718422 chr7:66359269 A/G cg10756647 chr7:56101905 PSPH 0.63 8.62 0.42 2.51e-16 Corneal structure; LIHC cis rs1577917 0.771 rs9362230 chr6:86305013 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.98 -0.54 7.53e-28 Response to antipsychotic treatment; LIHC cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg15691649 chr6:25882328 NA -0.97 -15.09 -0.63 8.46e-40 Urate levels; LIHC cis rs1395 0.634 rs72817542 chr2:27526681 C/G cg17158414 chr2:27665306 KRTCAP3 -0.51 -6.12 -0.31 2.59e-9 Blood metabolite levels; LIHC trans rs2744203 1.000 rs57058824 chr6:104649911 C/T cg27088726 chr16:83171155 CDH13 -0.46 -6.08 -0.31 3.14e-9 IgG glycosylation; LIHC cis rs4409675 0.576 rs7520860 chr1:28232952 C/A cg23691781 chr1:28212827 C1orf38 0.3 7.27 0.37 2.43e-12 Corneal astigmatism; LIHC cis rs8064299 0.597 rs2166703 chr17:72781812 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.82 15.1 0.63 8.08e-40 Monocyte count; LIHC cis rs16828019 0.777 rs3738369 chr1:41486408 G/A cg03387723 chr1:41708464 SCMH1 -0.39 -6.16 -0.32 2.05e-9 Intelligence (multi-trait analysis); LIHC cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg07636037 chr3:49044803 WDR6 0.78 13.21 0.58 1.77e-32 Menarche (age at onset); LIHC cis rs798554 0.655 rs798492 chr7:2799184 C/T cg13628971 chr7:2884303 GNA12 -0.38 -6.01 -0.31 4.72e-9 Height; LIHC cis rs2292096 0.636 rs6427859 chr1:200780153 C/A cg11814564 chr1:200748674 CAMSAP1L1 -0.54 -10.37 -0.49 4.26e-22 Epilepsy; LIHC cis rs240110 0.548 rs12190574 chr6:101173842 T/G cg09795085 chr6:101329169 ASCC3 -0.49 -6.65 -0.34 1.13e-10 Neuroticism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22583711 chr7:154795321 PAXIP1;LOC202781 -0.39 -6.68 -0.34 9.85e-11 Pancreatic cancer; LIHC cis rs6430585 0.528 rs7606267 chr2:136668123 T/C cg07305463 chr2:136567211 LCT -0.38 -6.02 -0.31 4.47e-9 Corneal structure; LIHC cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg25072359 chr17:41440525 NA 0.38 5.96 0.31 6.14e-9 Menopause (age at onset); LIHC cis rs11792861 0.781 rs28361106 chr9:111762385 T/C cg13535736 chr9:111863775 C9orf5 -0.41 -6.11 -0.31 2.68e-9 Menarche (age at onset); LIHC cis rs67311347 0.635 rs73071706 chr3:40288190 C/A cg13409248 chr3:40428643 ENTPD3 0.45 7.28 0.37 2.25e-12 Renal cell carcinoma; LIHC cis rs904251 0.523 rs9369005 chr6:37483109 A/G cg25019722 chr6:37503610 NA -0.32 -5.74 -0.3 2.09e-8 Cognitive performance; LIHC cis rs79149102 0.579 rs12592477 chr15:75292699 C/T cg15902774 chr15:75289873 SCAMP5 0.41 6.04 0.31 4.13e-9 Lung cancer; LIHC cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg12311636 chr6:118886798 C6orf204 -0.55 -6.29 -0.32 9.78e-10 Diastolic blood pressure; LIHC cis rs9630089 0.521 rs4917761 chr10:98967236 C/T cg25902810 chr10:99078978 FRAT1 0.42 5.86 0.3 1.09e-8 Neutrophil percentage of white cells; LIHC cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.04 -0.31 4.11e-9 Colorectal cancer; LIHC cis rs7095944 0.582 rs10901823 chr10:126488660 C/T cg20435097 chr10:126320824 FAM53B 0.34 5.93 0.31 7.58e-9 Asthma; LIHC cis rs4474465 0.850 rs10793326 chr11:78255422 A/C cg02023728 chr11:77925099 USP35 -0.36 -6.21 -0.32 1.53e-9 Alzheimer's disease (survival time); LIHC cis rs7586673 0.930 rs2884364 chr2:161977647 G/A cg21518248 chr2:162101506 NA 0.42 6.28 0.32 1.01e-9 Intelligence (multi-trait analysis); LIHC cis rs9326778 0.520 rs4957818 chr5:108828856 C/G cg17395555 chr5:108820864 NA -0.36 -6.13 -0.31 2.48e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC cis rs1865760 0.963 rs9356991 chr6:25901758 C/A cg17691542 chr6:26056736 HIST1H1C 0.38 5.75 0.3 2.02e-8 Height; LIHC cis rs12478296 1.000 rs55767645 chr2:242999350 G/A cg18898632 chr2:242989856 NA -0.72 -8.77 -0.43 8.53e-17 Obesity-related traits; LIHC trans rs13113518 0.812 rs6849474 chr4:56318462 G/A cg15358633 chr12:38710606 ALG10B 0.44 6.23 0.32 1.33e-9 Height; LIHC cis rs7618501 0.722 rs9853458 chr3:49783211 A/C cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC cis rs2239547 0.522 rs2581797 chr3:52972468 C/T cg11645453 chr3:52864694 ITIH4 -0.23 -5.94 -0.31 7.17e-9 Schizophrenia; LIHC cis rs713477 0.967 rs4901568 chr14:55912789 T/A cg13175173 chr14:55914753 NA -0.35 -8.14 -0.4 7.56e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs9733 0.596 rs72702573 chr1:150689050 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs11764590 0.694 rs10276536 chr7:2086960 C/T cg23043544 chr7:2124092 MAD1L1 -0.39 -6.33 -0.32 7.91e-10 Neuroticism; LIHC cis rs714027 0.534 rs140124 chr22:30143693 G/C cg01021169 chr22:30184971 ASCC2 -0.31 -5.79 -0.3 1.59e-8 Lymphocyte counts; LIHC cis rs7246865 0.906 rs11666569 chr19:17214073 A/G cg16202187 chr19:17186497 HAUS8;MYO9B -0.4 -6.02 -0.31 4.41e-9 Reticulocyte fraction of red cells; LIHC cis rs7847628 0.587 rs1060817 chr9:123583192 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.98 19.58 0.73 8.45e-58 Birth weight; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27304813 chr3:120068385 LRRC58 0.47 6.99 0.35 1.41e-11 Pancreatic cancer; LIHC trans rs72829446 0.530 rs8075007 chr17:7374507 A/T cg08566640 chr11:64091735 NA -0.74 -6.67 -0.34 1.02e-10 Androgen levels; LIHC cis rs798554 0.797 rs798488 chr7:2802522 T/C cg19346786 chr7:2764209 NA -0.46 -6.98 -0.35 1.58e-11 Height; LIHC trans rs2727020 0.635 rs7124266 chr11:49280857 T/G cg03929089 chr4:120376271 NA 0.67 9.95 0.47 1.15e-20 Coronary artery disease; LIHC cis rs4819852 0.958 rs1034564 chr22:19984013 A/G cg07821417 chr22:19972146 ARVCF -0.45 -6.72 -0.34 7.45e-11 Pulse pressure; LIHC cis rs5769765 0.773 rs6520065 chr22:50294470 A/T cg26441486 chr22:50317300 CRELD2 0.35 6.29 0.32 9.46e-10 Schizophrenia; LIHC cis rs870825 0.929 rs72689278 chr4:185593718 C/T cg04058563 chr4:185651563 MLF1IP 0.86 7.3 0.37 1.99e-12 Blood protein levels; LIHC trans rs561341 1.000 rs4795668 chr17:30244554 G/A cg20587970 chr11:113659929 NA -0.74 -8.29 -0.41 2.64e-15 Hip circumference adjusted for BMI; LIHC cis rs6582630 0.519 rs8186992 chr12:38325848 C/T cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.47e-14 Drug-induced liver injury (flucloxacillin); LIHC trans rs2388896 0.836 rs1243418 chr10:8966800 A/C cg02781394 chr13:30880900 KATNAL1 -0.49 -6.7 -0.34 8.64e-11 Tetralogy of Fallot; LIHC cis rs10744422 1.000 rs4759382 chr12:123347609 C/T cg07706471 chr12:123319906 HIP1R 0.55 7.36 0.37 1.42e-12 Schizophrenia; LIHC cis rs9733 0.818 rs12403609 chr1:150676485 T/C cg13175981 chr1:150552382 MCL1 0.52 8.08 0.4 1.16e-14 Tonsillectomy; LIHC cis rs10504229 0.953 rs59034808 chr8:58185337 T/C cg20607798 chr8:58055168 NA 0.46 5.81 0.3 1.44e-8 Developmental language disorder (linguistic errors); LIHC cis rs3008870 0.727 rs4582760 chr1:67464394 G/A cg08660285 chr1:67390436 MIER1;WDR78 -0.64 -10.77 -0.5 1.75e-23 Lymphocyte percentage of white cells; LIHC cis rs644148 0.676 rs2571114 chr19:44997579 A/G cg15540054 chr19:45004280 ZNF180 -0.4 -6.0 -0.31 5.08e-9 Personality dimensions; LIHC cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg03452623 chr4:187889614 NA -0.32 -8.31 -0.41 2.33e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7639513 0.767 rs9861271 chr3:12707620 A/C cg23032965 chr3:12705835 RAF1 0.65 7.85 0.39 5.27e-14 Itch intensity from mosquito bite; LIHC cis rs72781680 1.000 rs72798417 chr2:24188656 C/T cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs4907240 0.961 rs66727130 chr2:97324991 G/C cg26665480 chr2:98280029 ACTR1B -0.4 -5.95 -0.31 6.82e-9 Event-related brain oscillations; LIHC cis rs7131987 0.903 rs11050153 chr12:29405148 T/C cg00204748 chr12:29376779 FAR2 0.44 8.48 0.42 7.11e-16 QT interval; LIHC cis rs7903847 0.620 rs10882907 chr10:99125788 C/G cg08345082 chr10:99160200 RRP12 0.35 5.83 0.3 1.27e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs7618501 0.633 rs9866695 chr3:50069452 G/T cg21467203 chr3:49911342 NA 0.42 7.6 0.38 2.84e-13 Intelligence (multi-trait analysis); LIHC cis rs6545883 0.929 rs13413337 chr2:61747123 A/G cg14146966 chr2:61757674 XPO1 0.48 8.47 0.42 7.3e-16 Tuberculosis; LIHC cis rs7772486 0.875 rs9373485 chr6:146401429 A/T cg05347473 chr6:146136440 FBXO30 0.38 5.95 0.31 6.52e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg06238570 chr21:40685208 BRWD1 -0.48 -7.63 -0.38 2.31e-13 Cognitive function; LIHC cis rs7107174 0.681 rs10751288 chr11:78072658 A/T cg02023728 chr11:77925099 USP35 0.46 8.81 0.43 6.43e-17 Testicular germ cell tumor; LIHC cis rs79149102 0.737 rs74450883 chr15:75193432 A/G cg16226627 chr15:75307476 SCAMP5 0.44 6.23 0.32 1.35e-9 Lung cancer; LIHC cis rs826838 1.000 rs9795768 chr12:39012479 T/C cg26384229 chr12:38710491 ALG10B 0.89 11.91 0.54 1.38e-27 Heart rate; LIHC cis rs9926296 0.744 rs164749 chr16:89708224 A/C cg03605463 chr16:89740564 NA 0.39 5.78 0.3 1.73e-8 Vitiligo; LIHC cis rs1789 0.868 rs4631041 chr4:15673395 A/T cg16509355 chr4:15471240 CC2D2A -0.46 -7.02 -0.35 1.23e-11 Blood protein levels; LIHC cis rs4820539 1.000 rs4822358 chr22:23474795 A/G cg21100191 chr22:23484243 RTDR1 0.92 17.14 0.68 5.72e-48 Bone mineral density; LIHC cis rs4423214 1.000 rs2002063 chr11:71163476 T/C cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs4908760 0.792 rs4908505 chr1:8728864 G/A cg20416874 chr1:8611966 RERE -0.66 -13.75 -0.6 1.52e-34 Vitiligo; LIHC cis rs754466 0.580 rs10824576 chr10:79566040 G/C cg17075019 chr10:79541650 NA -0.79 -14.12 -0.61 5.27e-36 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2380220 0.576 rs4368819 chr6:96031109 T/G cg04719120 chr6:96025338 MANEA 0.7 8.25 0.41 3.4e-15 Behavioural disinhibition (generation interaction); LIHC cis rs116095464 0.558 rs10057492 chr5:239503 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.71 -0.5 2.89e-23 Breast cancer; LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs7918232 0.825 rs4749233 chr10:27467967 G/A cg14240646 chr10:27532245 ACBD5 -0.66 -6.29 -0.32 9.9e-10 Breast cancer; LIHC cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg26818010 chr10:134567672 INPP5A -0.7 -8.68 -0.43 1.59e-16 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs116095464 0.558 rs62344300 chr5:246336 A/G cg22857025 chr5:266934 NA -1.48 -18.17 -0.7 4.09e-52 Breast cancer; LIHC cis rs7829975 0.593 rs2921077 chr8:8304502 C/T cg06636001 chr8:8085503 FLJ10661 0.59 9.41 0.45 7.22e-19 Mood instability; LIHC cis rs9296092 0.500 rs9469503 chr6:33527234 G/T cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs6831352 0.918 rs17817958 chr4:100061245 A/C cg12011299 chr4:100065546 ADH4 0.44 7.03 0.36 1.15e-11 Alcohol dependence; LIHC cis rs10744422 1.000 rs897385 chr12:123341297 A/G cg18912006 chr12:123335444 HIP1R -0.64 -7.67 -0.38 1.78e-13 Schizophrenia; LIHC cis rs7131987 0.903 rs7302129 chr12:29415280 A/T cg12903224 chr12:29470962 FAR2 -0.41 -6.45 -0.33 3.89e-10 QT interval; LIHC cis rs9640161 0.617 rs73170169 chr7:150008036 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.5 -8.24 -0.41 3.62e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs74544699 1.000 rs76595330 chr4:74801272 T/G cg02530824 chr4:74847766 PF4 0.65 6.72 0.34 7.77e-11 Growth-regulated protein alpha levels; LIHC cis rs854765 0.619 rs1101727 chr17:18016148 T/C cg04398451 chr17:18023971 MYO15A -0.7 -12.17 -0.55 1.5e-28 Total body bone mineral density; LIHC cis rs2108622 0.727 rs7253684 chr19:15981126 C/T cg13772218 chr19:15982569 NA 0.37 7.83 0.39 6.2e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs1401999 1.000 rs939337 chr3:183701147 G/C cg05044414 chr3:183734942 ABCC5 0.33 5.88 0.3 9.51e-9 Anterior chamber depth; LIHC cis rs7100689 0.725 rs2487074 chr10:82064104 A/G cg00277334 chr10:82204260 NA -0.55 -6.86 -0.35 3.31e-11 Post bronchodilator FEV1; LIHC cis rs4665809 0.938 rs35844686 chr2:26304949 A/G cg04944784 chr2:26401820 FAM59B 0.58 6.4 0.33 5.01e-10 Gut microbiome composition (summer); LIHC cis rs2522056 1.000 rs2706381 chr5:131810619 C/T cg24060327 chr5:131705240 SLC22A5 0.54 7.38 0.37 1.24e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs6088580 0.634 rs6059878 chr20:33087166 A/T cg08999081 chr20:33150536 PIGU 0.67 13.46 0.59 1.89e-33 Glomerular filtration rate (creatinine); LIHC cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.63 -10.18 -0.48 1.88e-21 Tonsillectomy; LIHC cis rs2749592 0.918 rs4934590 chr10:37877569 T/C cg25427524 chr10:38739819 LOC399744 0.55 9.19 0.44 3.94e-18 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg12016809 chr21:47604291 C21orf56 -0.47 -7.32 -0.37 1.75e-12 Testicular germ cell tumor; LIHC cis rs3768617 0.811 rs6674729 chr1:183059143 C/T ch.1.3577855R chr1:183094577 LAMC1 0.49 7.78 0.39 8.8e-14 Fuchs's corneal dystrophy; LIHC cis rs2257205 0.667 rs6503874 chr17:56780459 C/G cg12560992 chr17:57184187 TRIM37 0.72 7.97 0.4 2.33e-14 Pancreatic cancer; LIHC cis rs1215050 0.765 rs1530905 chr4:98805705 A/G cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.86e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7264396 0.635 rs2064724 chr20:34522520 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.62 -0.5 6.08e-23 Total cholesterol levels; LIHC cis rs12594515 1.000 rs11855562 chr15:45995659 C/T cg01629716 chr15:45996671 NA 0.51 9.08 0.44 8.99e-18 Waist circumference;Weight; LIHC cis rs769267 0.930 rs7256149 chr19:19566255 T/C cg03709012 chr19:19516395 GATAD2A 1.02 18.35 0.7 7.4e-53 Tonsillectomy; LIHC cis rs12497850 0.931 rs10780033 chr3:48891275 T/C cg06212747 chr3:49208901 KLHDC8B 0.55 7.12 0.36 6.57e-12 Parkinson's disease; LIHC cis rs4927850 0.957 rs4927851 chr3:195751853 A/G cg01181863 chr3:195395398 SDHAP2 -0.52 -6.69 -0.34 9.34e-11 Pancreatic cancer; LIHC cis rs10876993 0.928 rs1689586 chr12:58079586 A/T cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.25 -0.32 1.23e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs921968 0.643 rs2303561 chr2:219527005 C/T cg02985541 chr2:219472218 PLCD4 -0.43 -8.09 -0.4 1.05e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs9486719 0.948 rs2472904 chr6:96874962 T/G cg06623918 chr6:96969491 KIAA0776 0.74 7.15 0.36 5.14e-12 Migraine;Coronary artery disease; LIHC cis rs9394841 0.667 rs9471667 chr6:41776681 T/C cg08135965 chr6:41755394 TOMM6 0.43 5.72 0.3 2.38e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC trans rs11148252 0.574 rs2038826 chr13:53280013 G/A cg18335740 chr13:41363409 SLC25A15 0.56 10.31 0.49 7e-22 Lewy body disease; LIHC cis rs9457247 1.000 rs385863 chr6:167386615 C/G cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs7107174 1.000 rs7116698 chr11:77995191 T/C cg02023728 chr11:77925099 USP35 0.51 9.79 0.47 4.25e-20 Testicular germ cell tumor; LIHC cis rs4450131 0.522 rs34209544 chr10:126350452 G/C cg20435097 chr10:126320824 FAM53B 0.66 11.98 0.54 7.24e-28 White blood cell count (basophil); LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg21548813 chr6:291882 DUSP22 -0.57 -7.69 -0.38 1.59e-13 Menopause (age at onset); LIHC cis rs12711979 0.509 rs12711972 chr2:3823786 T/C cg17052675 chr2:3827356 NA -0.7 -15.3 -0.64 1.32e-40 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs11971779 0.680 rs6962637 chr7:139051350 G/A cg07862535 chr7:139043722 LUC7L2 0.6 10.31 0.49 6.97e-22 Diisocyanate-induced asthma; LIHC cis rs9394841 0.692 rs2395795 chr6:41802354 G/A cg17623882 chr6:41773611 USP49 -0.43 -5.85 -0.3 1.13e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg06873352 chr17:61820015 STRADA 0.6 9.31 0.45 1.59e-18 Height; LIHC cis rs10489202 0.632 rs275137 chr1:168051266 A/C cg24449463 chr1:168025552 DCAF6 0.66 10.21 0.48 1.51e-21 Schizophrenia; LIHC cis rs959260 1.000 rs7216423 chr17:73365671 T/C cg20590849 chr17:73267439 MIF4GD -0.54 -5.83 -0.3 1.25e-8 Systemic lupus erythematosus; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg27432699 chr2:27873401 GPN1 -0.49 -7.07 -0.36 8.55e-12 Total body bone mineral density; LIHC cis rs1707322 0.752 rs4660313 chr1:46110841 A/G cg06784218 chr1:46089804 CCDC17 -0.42 -7.68 -0.38 1.74e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2380220 0.872 rs115871915 chr6:95934180 T/C cg15832292 chr6:96025679 MANEA -0.6 -6.73 -0.34 7.25e-11 Behavioural disinhibition (generation interaction); LIHC cis rs28595532 0.702 rs116320061 chr4:119384600 C/T cg21605333 chr4:119757512 SEC24D 1.03 7.76 0.39 9.66e-14 Cannabis dependence symptom count; LIHC cis rs17739167 0.569 rs11638621 chr15:42228226 C/T cg20935245 chr15:42234343 EHD4 0.39 7.16 0.36 4.85e-12 Monocyte count; LIHC cis rs7772486 0.686 rs9390347 chr6:146044747 G/T cg23711669 chr6:146136114 FBXO30 -0.64 -11.7 -0.53 8.18e-27 Lobe attachment (rater-scored or self-reported); LIHC trans rs116095464 0.558 rs13356367 chr5:242395 C/T cg00938859 chr5:1591904 SDHAP3 0.57 7.07 0.36 8.57e-12 Breast cancer; LIHC cis rs6088580 0.634 rs4258875 chr20:32924895 C/A cg08999081 chr20:33150536 PIGU -0.65 -12.41 -0.56 1.87e-29 Glomerular filtration rate (creatinine); LIHC cis rs9814567 0.806 rs12637301 chr3:134317966 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs644799 0.965 rs11021305 chr11:95498269 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 15.61 0.65 7.19e-42 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4969178 0.895 rs2292640 chr17:76396610 G/A cg20026190 chr17:76395443 PGS1 0.46 7.3 0.37 2.06e-12 HDL cholesterol levels; LIHC cis rs6545883 0.965 rs2305155 chr2:61729258 A/G cg15711740 chr2:61764176 XPO1 -0.43 -6.08 -0.31 3.17e-9 Tuberculosis; LIHC cis rs17539620 0.628 rs11541340 chr6:154831572 C/G cg20019720 chr6:154832845 CNKSR3 0.44 6.48 0.33 3.14e-10 Lipoprotein (a) levels; LIHC cis rs950169 0.580 rs36126054 chr15:85177723 T/G cg03959625 chr15:84868606 LOC388152 0.44 6.11 0.31 2.64e-9 Schizophrenia; LIHC cis rs875971 0.862 rs13232191 chr7:65986648 A/G cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.38e-11 Aortic root size; LIHC cis rs12744310 1.000 rs12756822 chr1:41777327 A/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs600806 0.850 rs10858095 chr1:109962642 G/C cg23091122 chr1:110024289 SYPL2 -0.48 -6.42 -0.33 4.54e-10 Intelligence (multi-trait analysis); LIHC cis rs17685 0.625 rs1639630 chr7:75730499 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.41 -0.37 9.97e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2607426 0.681 rs2607418 chr19:41257396 A/G cg20631044 chr19:41255890 C19orf54;SNRPA 0.56 6.68 0.34 9.47e-11 Blood protein levels; LIHC cis rs7116495 1.000 rs59339387 chr11:71558232 A/G cg26138937 chr11:71823887 C11orf51 0.65 6.02 0.31 4.41e-9 Severe influenza A (H1N1) infection; LIHC cis rs55665837 0.701 rs11023265 chr11:14616038 C/T cg00085434 chr11:14927489 NA 0.43 6.05 0.31 3.74e-9 Vitamin D levels; LIHC cis rs11785400 1.000 rs3802232 chr8:143746701 A/G cg24634471 chr8:143751801 JRK 0.51 8.2 0.41 4.77e-15 Schizophrenia; LIHC cis rs7116495 1.000 rs542752 chr11:71810644 T/A cg26138937 chr11:71823887 C11orf51 0.82 8.2 0.41 4.99e-15 Severe influenza A (H1N1) infection; LIHC cis rs7772486 0.875 rs9403768 chr6:146406458 A/C cg05347473 chr6:146136440 FBXO30 0.38 6.08 0.31 3.15e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg18110333 chr6:292329 DUSP22 -0.55 -7.27 -0.37 2.47e-12 Menopause (age at onset); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg06679777 chr13:30881210 KATNAL1 -0.45 -6.16 -0.32 2e-9 Bilirubin levels; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg13981034 chr14:21860709 SNORD9;CHD8 0.44 6.33 0.32 7.57e-10 Migraine with aura; LIHC cis rs700651 0.789 rs10190226 chr2:198901564 A/G cg10820045 chr2:198174542 NA -0.42 -6.17 -0.32 1.95e-9 Intracranial aneurysm; LIHC cis rs7918232 0.882 rs6415983 chr10:27357211 A/G cg14442939 chr10:27389572 ANKRD26 0.64 6.18 0.32 1.86e-9 Breast cancer; LIHC cis rs11098499 0.954 rs17006190 chr4:120418838 C/G cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC cis rs7937890 0.559 rs2597206 chr11:14477538 A/C cg02886208 chr11:14281011 SPON1 -0.46 -6.58 -0.34 1.75e-10 Mitochondrial DNA levels; LIHC trans rs2797369 0.766 rs2629978 chr6:101684574 A/G cg18702971 chr22:29920546 THOC5 0.58 6.15 0.32 2.2e-9 Renal function-related traits (eGRFcrea); LIHC trans rs17184557 0.914 rs77202769 chr18:67108558 T/C cg22968167 chr11:4945873 OR51G1 -0.24 -6.06 -0.31 3.69e-9 Osteoporosis-related phenotypes; LIHC cis rs6500637 0.631 rs12921187 chr16:4943019 T/G cg08329684 chr16:4932620 PPL -0.42 -7.32 -0.37 1.83e-12 Cancer; LIHC cis rs9549367 0.789 rs7338235 chr13:113888687 T/C cg00898013 chr13:113819073 PROZ -0.43 -7.46 -0.37 7.18e-13 Platelet distribution width; LIHC cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg03264133 chr6:25882463 NA -0.63 -8.9 -0.43 3.25e-17 Blood metabolite levels; LIHC cis rs9814567 0.806 rs11927539 chr3:134319448 C/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11758351 0.866 rs55815656 chr6:26207303 G/A cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 8.89e-15 Prudent dietary pattern; LIHC cis rs4742903 0.935 rs1507507 chr9:106949429 A/G cg14250997 chr9:106856677 SMC2 0.35 5.92 0.3 7.9e-9 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07551314 chr1:26190155 PAQR7 0.41 6.04 0.31 4.08e-9 Longevity; LIHC cis rs1000083 1.000 rs1000083 chr5:96533469 A/G ch.5.96698337R chr5:96672581 NA 0.87 7.04 0.36 1.07e-11 Cisplatin-induced ototoxicity; LIHC cis rs3796352 1.000 rs13058817 chr3:53024139 C/T cg07884673 chr3:53033167 SFMBT1 0.94 6.69 0.34 9.22e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7534824 0.625 rs10493939 chr1:101378026 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.64 6.55 0.33 2.15e-10 Refractive astigmatism; LIHC cis rs2404602 0.655 rs34748201 chr15:77221530 G/T cg23625390 chr15:77176239 SCAPER 0.35 5.75 0.3 1.98e-8 Blood metabolite levels; LIHC cis rs311392 0.554 rs376765 chr8:55097188 A/G cg20636351 chr8:55087400 NA -0.36 -7.33 -0.37 1.66e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs2832191 0.791 rs57721945 chr21:30498744 T/C cg08807101 chr21:30365312 RNF160 -0.57 -8.9 -0.43 3.44e-17 Dental caries; LIHC cis rs7903847 0.642 rs11814021 chr10:99158386 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.43 -0.33 4.2e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7191700 0.644 rs12149160 chr16:11439303 G/T cg00044050 chr16:11439710 C16orf75 -0.49 -7.3 -0.37 2.05e-12 Multiple sclerosis; LIHC cis rs2749592 0.550 rs7917262 chr10:37874602 A/C cg00409905 chr10:38381863 ZNF37A 0.51 8.54 0.42 4.38e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs11969893 0.649 rs1321204 chr6:101468591 A/G cg12253828 chr6:101329408 ASCC3 0.57 6.79 0.34 4.97e-11 Economic and political preferences (immigration/crime); LIHC cis rs7582720 1.000 rs72936862 chr2:203786812 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg16103275 chr6:290800 DUSP22 0.51 6.95 0.35 1.84e-11 Menopause (age at onset); LIHC cis rs7072216 0.763 rs7091709 chr10:100167605 G/A cg26618903 chr10:100175079 PYROXD2 -0.38 -6.11 -0.31 2.79e-9 Metabolite levels; LIHC cis rs11608355 0.515 rs35691047 chr12:109932585 C/T cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs2180341 0.680 rs9388554 chr6:127576234 C/G cg27446573 chr6:127587934 RNF146 0.66 10.01 0.48 7.56e-21 Breast cancer; LIHC trans rs561341 0.505 rs28708703 chr17:30386845 C/G cg20587970 chr11:113659929 NA -1.07 -10.03 -0.48 6.2e-21 Hip circumference adjusted for BMI; LIHC cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9534288 0.797 rs6561278 chr13:46572937 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg14580349 chr1:25664531 TMEM50A 0.39 6.05 0.31 3.86e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6570726 0.935 rs434298 chr6:145846873 G/A cg23711669 chr6:146136114 FBXO30 0.53 9.28 0.45 2.02e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg21782813 chr7:2030301 MAD1L1 0.55 10.18 0.48 1.98e-21 Bipolar disorder and schizophrenia; LIHC cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC trans rs2832191 0.716 rs2692625 chr21:30446360 C/G cg14791747 chr16:20752902 THUMPD1 -0.47 -6.53 -0.33 2.42e-10 Dental caries; LIHC cis rs1144333 0.655 rs3765682 chr1:76333172 T/C cg10523679 chr1:76189770 ACADM 0.45 6.01 0.31 4.88e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs12477438 0.765 rs56167745 chr2:99600478 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.33 -0.49 5.77e-22 Chronic sinus infection; LIHC cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg00149659 chr3:10157352 C3orf10 0.49 5.82 0.3 1.39e-8 Alzheimer's disease; LIHC cis rs9486715 1.000 rs3798297 chr6:97062835 C/T cg18709589 chr6:96969512 KIAA0776 -0.36 -6.14 -0.32 2.23e-9 Headache; LIHC cis rs11711311 0.747 rs7638378 chr3:113343630 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.5 -0.33 2.92e-10 IgG glycosylation; LIHC cis rs739401 0.572 rs389128 chr11:3083873 G/T cg20651018 chr11:3035856 CARS -0.38 -6.26 -0.32 1.14e-9 Longevity; LIHC cis rs4759375 0.920 rs28786830 chr12:123860472 C/G cg00376283 chr12:123451042 ABCB9 0.49 6.31 0.32 8.57e-10 HDL cholesterol; LIHC cis rs2404602 0.647 rs907594 chr15:77197745 C/A cg23625390 chr15:77176239 SCAPER -0.54 -9.21 -0.45 3.35e-18 Blood metabolite levels; LIHC cis rs74233809 1.000 rs35125602 chr10:104656039 G/A cg03493300 chr10:104813866 CNNM2 0.45 5.92 0.3 7.89e-9 Birth weight; LIHC cis rs16828019 0.852 rs3766324 chr1:41588653 A/G cg03387723 chr1:41708464 SCMH1 -0.42 -6.82 -0.35 4.06e-11 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg05896524 chr21:47604654 C21orf56 -0.5 -8.12 -0.4 8.79e-15 Testicular germ cell tumor; LIHC cis rs1008375 0.897 rs1006723 chr4:17618524 G/A cg16339924 chr4:17578868 LAP3 0.42 5.92 0.3 8.04e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3806843 1.000 rs10066278 chr5:140156318 A/C cg19875535 chr5:140030758 IK 0.37 6.09 0.31 3.05e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg02869306 chr7:64672164 INTS4L1 -0.29 -6.38 -0.33 5.87e-10 Calcium levels; LIHC cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.18 -0.55 1.37e-28 Alzheimer's disease; LIHC cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs7523273 0.606 rs2761433 chr1:207917361 G/A cg22525895 chr1:207977042 MIR29B2 0.66 10.79 0.5 1.49e-23 Schizophrenia; LIHC cis rs7107174 1.000 rs7128666 chr11:78102363 A/T cg02023728 chr11:77925099 USP35 0.46 8.51 0.42 5.64e-16 Testicular germ cell tumor; LIHC cis rs10861342 1.000 rs11112374 chr12:105510285 G/T cg23923672 chr12:105501055 KIAA1033 0.69 8.49 0.42 6.56e-16 IgG glycosylation; LIHC cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.85 -11.62 -0.53 1.59e-26 Alzheimer's disease; LIHC trans rs2727020 0.688 rs4929894 chr11:49196333 G/C cg18944383 chr4:111397179 ENPEP 0.25 6.08 0.31 3.14e-9 Coronary artery disease; LIHC cis rs10089 1.000 rs17164310 chr5:127493679 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.52 6.37 0.33 6.22e-10 Ileal carcinoids; LIHC cis rs7552404 1.000 rs2133134 chr1:76179587 G/A cg10523679 chr1:76189770 ACADM 0.64 8.64 0.42 2.23e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10504229 0.871 rs7002070 chr8:58153817 A/G cg02290350 chr8:58132656 NA 0.38 8.28 0.41 2.75e-15 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 12.28 0.55 5.66e-29 Prudent dietary pattern; LIHC cis rs17818399 0.815 rs62136873 chr2:46861237 G/A cg02822958 chr2:46747628 ATP6V1E2 0.39 5.82 0.3 1.37e-8 Height; LIHC cis rs2569991 0.588 rs62240725 chr3:12929360 A/G cg22481960 chr3:13008800 IQSEC1 0.43 7.46 0.37 7.14e-13 Periodontitis (DPAL); LIHC cis rs1198430 0.599 rs946269 chr1:23769359 T/C cg13183780 chr1:23809682 ASAP3 -0.38 -6.56 -0.33 1.98e-10 Total cholesterol levels; LIHC cis rs62458065 0.713 rs62463967 chr7:32498329 G/A cg06627557 chr7:32535165 LSM5;AVL9 -0.63 -6.09 -0.31 3.02e-9 Metabolite levels (HVA/MHPG ratio); LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg14283194 chr7:91763737 CYP51A1 -0.42 -6.22 -0.32 1.43e-9 Body mass index; LIHC cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg12310025 chr6:25882481 NA -0.63 -8.89 -0.43 3.66e-17 Blood metabolite levels; LIHC cis rs6546550 0.901 rs897120 chr2:70160982 C/T cg02498382 chr2:70120550 SNRNP27 0.43 7.33 0.37 1.64e-12 Prevalent atrial fibrillation; LIHC cis rs7116495 0.609 rs10736783 chr11:71654143 G/A cg07596299 chr11:71824057 C11orf51 -0.75 -5.72 -0.3 2.3e-8 Severe influenza A (H1N1) infection; LIHC cis rs9359856 0.636 rs1179896 chr6:90318610 T/C cg13799429 chr6:90582589 CASP8AP2 -0.64 -6.67 -0.34 1.02e-10 Bipolar disorder; LIHC cis rs763121 0.853 rs5757226 chr22:39070550 T/C cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs2760061 0.583 rs708118 chr1:228201801 A/G cg02753203 chr1:228287806 NA -0.61 -10.86 -0.51 8.37e-24 Diastolic blood pressure; LIHC trans rs2262909 0.962 rs73019844 chr19:22249925 T/C cg05197062 chr11:11642011 GALNTL4 0.42 6.08 0.31 3.17e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs11190604 1.000 rs2489048 chr10:102348497 G/T cg07080220 chr10:102295463 HIF1AN 0.56 7.92 0.39 3.27e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7582180 0.629 rs12991172 chr2:100941671 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC trans rs4714291 0.802 rs7759622 chr6:40114735 C/T cg02267698 chr19:7991119 CTXN1 -0.39 -6.56 -0.33 2.04e-10 Strep throat; LIHC cis rs3749237 0.595 rs7621003 chr3:49411404 T/C cg07636037 chr3:49044803 WDR6 0.5 7.53 0.38 4.44e-13 Resting heart rate; LIHC cis rs2073300 1.000 rs6137957 chr20:23437384 G/A cg12062639 chr20:23401060 NAPB 0.87 10.38 0.49 3.89e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs595982 0.559 rs17206714 chr19:49362001 T/A cg21252483 chr19:49399788 TULP2 -0.87 -9.86 -0.47 2.36e-20 Red cell distribution width; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg13409248 chr3:40428643 ENTPD3 0.48 7.86 0.39 4.91e-14 Renal cell carcinoma; LIHC cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg08888203 chr3:10149979 C3orf24 0.6 6.82 0.35 4.14e-11 Alzheimer's disease; LIHC cis rs2933343 0.679 rs1091938 chr3:128637025 T/C cg25356066 chr3:128598488 ACAD9 0.54 7.47 0.37 6.64e-13 IgG glycosylation; LIHC cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.04 -0.36 1.05e-11 Bipolar disorder; LIHC cis rs769267 0.930 rs2315022 chr19:19413381 A/G cg03709012 chr19:19516395 GATAD2A 0.93 15.59 0.64 9.01e-42 Tonsillectomy; LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg16822855 chr3:40428330 ENTPD3 0.32 5.72 0.3 2.27e-8 Renal cell carcinoma; LIHC cis rs1538970 0.851 rs2055145 chr1:45926495 C/G cg24296786 chr1:45957014 TESK2 -0.51 -7.63 -0.38 2.29e-13 Platelet count; LIHC cis rs26868 0.690 rs26835 chr16:2237549 C/T cg02248941 chr16:2239361 CASKIN1 0.43 8.87 0.43 4.24e-17 Height; LIHC cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg06697600 chr4:7070879 GRPEL1 -0.67 -10.79 -0.5 1.46e-23 Monocyte percentage of white cells; LIHC cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg03264133 chr6:25882463 NA -0.44 -6.77 -0.34 5.62e-11 Height; LIHC cis rs12249377 0.519 rs12259401 chr10:92594121 T/G cg14313238 chr10:92632228 RPP30 0.38 6.41 0.33 4.76e-10 White matter microstructure (global fractional anisotropy); LIHC cis rs796364 1.000 rs35220450 chr2:200780737 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.69 -6.43 -0.33 4.29e-10 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23797200 chr17:40174494 NKIRAS2 0.42 6.46 0.33 3.69e-10 Cognitive function; LIHC cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg18305652 chr10:134549665 INPP5A 0.43 6.4 0.33 5.14e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9916302 0.904 rs7221875 chr17:37543328 G/A cg00129232 chr17:37814104 STARD3 0.39 6.31 0.32 8.47e-10 Glomerular filtration rate (creatinine); LIHC cis rs7927771 1.000 rs7947730 chr11:47786184 C/T cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.39e-18 Subjective well-being; LIHC cis rs2658782 0.547 rs3020052 chr11:93055184 C/G cg15737290 chr11:93063684 CCDC67 0.45 5.96 0.31 6.23e-9 Pulmonary function decline; LIHC cis rs9911578 0.967 rs7502208 chr17:57165097 G/A cg12560992 chr17:57184187 TRIM37 0.97 17.97 0.7 2.53e-51 Intelligence (multi-trait analysis); LIHC cis rs4727027 0.835 rs11767810 chr7:148774433 T/A cg23583168 chr7:148888333 NA -0.66 -9.33 -0.45 1.36e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2153535 0.553 rs2984099 chr6:8637274 C/T cg23788917 chr6:8435910 SLC35B3 -0.53 -7.15 -0.36 5.37e-12 Motion sickness; LIHC cis rs6570726 0.791 rs6913727 chr6:145899826 A/G cg13319975 chr6:146136371 FBXO30 -0.4 -6.38 -0.33 5.85e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs798554 0.679 rs7784066 chr7:2819727 T/A cg19717773 chr7:2847554 GNA12 -0.41 -6.7 -0.34 8.35e-11 Height; LIHC cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg12310025 chr6:25882481 NA -0.42 -6.47 -0.33 3.3e-10 Height; LIHC cis rs2952156 0.959 rs2934952 chr17:37832366 G/A cg00129232 chr17:37814104 STARD3 -0.51 -9.38 -0.45 9.7e-19 Asthma; LIHC cis rs3096299 0.685 rs4785571 chr16:89565169 A/G cg00750074 chr16:89608354 SPG7 -0.41 -6.95 -0.35 1.86e-11 Multiple myeloma (IgH translocation); LIHC cis rs7223966 1.000 rs6504182 chr17:61823672 T/C cg05941027 chr17:61774174 LIMD2 0.32 6.61 0.34 1.44e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs916888 0.821 rs199525 chr17:44847834 T/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.72 6.71 0.34 8.05e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9899728 0.764 rs9660 chr17:73038746 A/G cg27626185 chr17:73056755 KCTD2 -0.61 -10.95 -0.51 4.14e-24 Alzheimer's disease or small vessel stroke; LIHC cis rs9309711 0.621 rs12993215 chr2:3473727 T/C cg04359351 chr2:3481828 TTC15 0.3 5.97 0.31 5.98e-9 Neurofibrillary tangles; LIHC cis rs910316 0.967 rs4899550 chr14:75647666 C/T cg11812906 chr14:75593930 NEK9 -0.73 -13.8 -0.6 9.43e-35 Height; LIHC cis rs2242116 1.000 rs2242116 chr3:46941116 A/G cg27129171 chr3:47204927 SETD2 0.49 7.66 0.38 1.98e-13 Birth weight; LIHC cis rs36051895 0.659 rs4495487 chr9:5072798 T/C cg02405213 chr9:5042618 JAK2 -0.68 -11.61 -0.53 1.72e-26 Pediatric autoimmune diseases; LIHC cis rs9296092 0.560 rs3846854 chr6:33528466 T/C cg13560919 chr6:33536144 NA -0.38 -6.48 -0.33 3.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs2292864 0.764 rs2292867 chr17:45357489 C/T cg18085866 chr17:45331354 ITGB3 -0.44 -5.73 -0.3 2.2e-8 Left atrial antero-posterior diameter; LIHC cis rs1577917 0.518 rs2475787 chr6:86415236 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.28 0.45 2e-18 Response to antipsychotic treatment; LIHC cis rs4654899 0.965 rs7512116 chr1:21501095 C/A cg08539965 chr1:21396338 EIF4G3 0.33 5.79 0.3 1.63e-8 Superior frontal gyrus grey matter volume; LIHC cis rs9457247 0.765 rs9457251 chr6:167426707 T/C cg12798992 chr6:167411361 FGFR1OP 0.49 7.47 0.37 6.63e-13 Crohn's disease; LIHC cis rs11971779 0.553 rs7799742 chr7:139051878 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs473651 0.506 rs561264 chr2:239329979 G/T cg18131467 chr2:239335373 ASB1 0.85 13.24 0.58 1.39e-32 Multiple system atrophy; LIHC cis rs9911578 0.967 rs12944948 chr17:56951474 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs17401966 0.931 rs17410217 chr1:10371854 A/G cg19773385 chr1:10388646 KIF1B -0.41 -7.33 -0.37 1.67e-12 Hepatocellular carcinoma; LIHC cis rs79149102 0.649 rs75985113 chr15:75379312 C/T cg16226627 chr15:75307476 SCAMP5 0.51 8.55 0.42 4.14e-16 Lung cancer; LIHC cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs9300255 0.543 rs520088 chr12:123522150 C/G cg00376283 chr12:123451042 ABCB9 0.62 8.45 0.42 8.23e-16 Neutrophil percentage of white cells; LIHC cis rs12594515 1.000 rs35182335 chr15:45995184 C/G cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs8072100 0.935 rs12150231 chr17:45717091 G/A cg08085267 chr17:45401833 C17orf57 0.57 8.44 0.42 9.23e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2997447 0.655 rs55820521 chr1:26374286 C/T cg19633962 chr1:26362018 EXTL1 -0.84 -9.08 -0.44 8.66e-18 QRS complex (12-leadsum); LIHC cis rs208520 1.000 rs208520 chr6:66952828 G/T cg07460842 chr6:66804631 NA -0.65 -6.99 -0.35 1.44e-11 Exhaled nitric oxide output; LIHC cis rs7085104 0.660 rs3781286 chr10:104595719 C/T cg15744005 chr10:104629667 AS3MT -0.39 -8.81 -0.43 6.53e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC trans rs10242455 0.557 rs73401516 chr7:99068351 C/A cg09045935 chr12:6379348 NA 0.83 6.86 0.35 3.19e-11 Blood metabolite levels; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.6 9.32 0.45 1.43e-18 Height; LIHC cis rs6912958 0.559 rs242270 chr6:88062190 C/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.59 -10.84 -0.51 9.68e-24 Monocyte percentage of white cells; LIHC cis rs240764 0.583 rs11155638 chr6:101203801 T/A cg09795085 chr6:101329169 ASCC3 -0.56 -8.06 -0.4 1.34e-14 Neuroticism; LIHC cis rs17106184 1.000 rs59029934 chr1:50992756 C/T cg07174182 chr1:51127561 FAF1 -0.7 -7.11 -0.36 6.97e-12 Type 2 diabetes; LIHC cis rs7613875 0.663 rs6762477 chr3:50093209 G/A cg21467203 chr3:49911342 NA 0.5 9.13 0.44 6.05e-18 Body mass index; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg00091569 chr3:40428383 ENTPD3 -0.39 -6.59 -0.34 1.62e-10 Renal cell carcinoma; LIHC trans rs7474896 0.616 rs2474561 chr10:38373544 C/T cg17830980 chr10:43048298 ZNF37B -0.44 -7.05 -0.36 9.78e-12 Obesity (extreme); LIHC cis rs9640161 0.702 rs1962004 chr7:150020381 G/A cg10018233 chr7:150070692 REPIN1 0.52 8.12 0.4 8.27e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs4407350 1.000 rs4386428 chr22:44922359 T/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.08 -0.31 3.15e-9 Intelligence (multi-trait analysis); LIHC cis rs6754311 0.593 rs10195620 chr2:136495619 A/T cg07169764 chr2:136633963 MCM6 -0.69 -10.0 -0.48 8.1e-21 Mosquito bite size; LIHC cis rs12586317 0.547 rs28589276 chr14:35478865 A/G cg05294307 chr14:35346193 BAZ1A -0.5 -7.42 -0.37 9.26e-13 Psoriasis; LIHC cis rs2032447 0.531 rs428469 chr6:25898624 G/A cg18357526 chr6:26021779 HIST1H4A 0.97 11.63 0.53 1.38e-26 Intelligence (multi-trait analysis); LIHC cis rs11190604 1.000 rs10883504 chr10:102280687 G/A cg07080220 chr10:102295463 HIF1AN 0.57 8.08 0.4 1.15e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg12751644 chr20:60527061 NA -0.35 -5.88 -0.3 9.88e-9 Body mass index; LIHC cis rs763121 0.889 rs1043402 chr22:38879688 G/A cg06022373 chr22:39101656 GTPBP1 0.62 10.48 0.49 1.79e-22 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25022925 chr5:126112600 LMNB1 0.47 6.51 0.33 2.66e-10 Lung function (FEV1/FVC); LIHC cis rs6456156 0.819 rs9457273 chr6:167520749 A/T cg07741184 chr6:167504864 NA -0.26 -6.28 -0.32 1e-9 Primary biliary cholangitis; LIHC cis rs57221529 0.766 rs72703026 chr5:572383 G/A cg09021430 chr5:549028 NA -0.45 -8.75 -0.43 9.7e-17 Lung disease severity in cystic fibrosis; LIHC cis rs11583043 0.831 rs6667818 chr1:101412313 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 9.45 0.46 5.4e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs78456975 0.506 rs13384333 chr2:1555531 A/C cg01028140 chr2:1542097 TPO -0.42 -6.63 -0.34 1.28e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs7647973 1.000 rs8897 chr3:49460407 A/G cg07636037 chr3:49044803 WDR6 0.52 6.61 0.34 1.52e-10 Menarche (age at onset); LIHC cis rs67460515 0.892 rs2054710 chr3:161090616 C/T cg17135325 chr3:160939158 NMD3 0.52 7.49 0.38 6.11e-13 Parkinson's disease; LIHC cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg00166722 chr3:10149974 C3orf24 0.54 6.28 0.32 1.02e-9 Alzheimer's disease; LIHC trans rs1814175 0.645 rs1851869 chr11:49960552 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs35306767 0.761 rs12773961 chr10:1013215 C/G cg20503657 chr10:835505 NA 0.86 7.95 0.39 2.75e-14 Eosinophil percentage of granulocytes; LIHC cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.43 5.83 0.3 1.27e-8 Electroencephalogram traits; LIHC cis rs5769765 0.837 rs4824110 chr22:50271631 T/A cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs921968 0.643 rs612874 chr2:219492924 T/C cg18887096 chr2:219472410 PLCD4 0.36 6.15 0.32 2.12e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs9457247 0.534 rs9355610 chr6:167383075 G/A cg12798992 chr6:167411361 FGFR1OP -0.45 -7.28 -0.37 2.28e-12 Crohn's disease; LIHC cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.81 0.3 1.43e-8 Bipolar disorder; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg03133777 chr2:170361364 BBS5 0.43 6.41 0.33 4.89e-10 Hepatitis; LIHC cis rs1801251 0.896 rs7573208 chr2:233696701 C/A cg08000102 chr2:233561755 GIGYF2 -0.75 -11.14 -0.52 8.36e-25 Coronary artery disease; LIHC cis rs6570726 0.905 rs396492 chr6:145816180 C/G cg23711669 chr6:146136114 FBXO30 0.5 8.71 0.43 1.35e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7100689 0.599 rs6585968 chr10:82139807 T/C cg01528321 chr10:82214614 TSPAN14 0.85 12.35 0.56 3.15e-29 Post bronchodilator FEV1; LIHC cis rs644799 0.965 rs10831426 chr11:95505888 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.8 0.47 3.77e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7727544 0.684 rs611084 chr5:131709739 A/C cg07395648 chr5:131743802 NA 0.31 6.52 0.33 2.46e-10 Blood metabolite levels; LIHC cis rs11864453 0.713 rs9925763 chr16:72142595 C/A cg01557791 chr16:72042693 DHODH -0.5 -8.16 -0.4 6.58e-15 Fibrinogen levels; LIHC cis rs7106204 0.800 rs6484026 chr11:24214633 G/A ch.11.24196551F chr11:24239977 NA 0.77 10.47 0.49 1.94e-22 Response to Homoharringtonine (cytotoxicity); LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC cis rs9733 0.744 rs11204725 chr1:150742700 T/C cg17724175 chr1:150552817 MCL1 -0.37 -7.3 -0.37 2e-12 Tonsillectomy; LIHC cis rs17125944 0.686 rs7144029 chr14:53333616 G/T cg00686598 chr14:53173677 PSMC6 -0.78 -8.72 -0.43 1.19e-16 Alzheimer's disease (late onset); LIHC cis rs910316 0.967 rs175505 chr14:75529619 C/T cg08847533 chr14:75593920 NEK9 -0.9 -19.42 -0.72 3.67e-57 Height; LIHC cis rs1144333 0.655 rs77244403 chr1:76304872 A/G cg03433033 chr1:76189801 ACADM 0.53 7.41 0.37 9.69e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs3857067 1.000 rs3846292 chr4:95027717 G/T cg11021082 chr4:95130006 SMARCAD1 -0.41 -7.35 -0.37 1.43e-12 QT interval; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23470272 chr19:14640395 TECR;MIR639 -0.46 -6.44 -0.33 3.98e-10 Pancreatic cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14592024 chr15:48624386 DUT 0.48 6.06 0.31 3.51e-9 Lung function (FEV1/FVC); LIHC cis rs939574 1.000 rs9989854 chr2:220086280 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.93 -10.58 -0.5 8.34e-23 Platelet distribution width; LIHC cis rs8114671 0.836 rs62213676 chr20:33612676 T/A cg07148914 chr20:33460835 GGT7 -0.55 -8.33 -0.41 2e-15 Height; LIHC trans rs11039798 0.920 rs11500574 chr11:48713986 A/T cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs9322817 0.902 rs963949 chr6:105174273 A/G cg02098413 chr6:105308735 HACE1 -0.38 -6.09 -0.31 3.03e-9 Thyroid stimulating hormone; LIHC cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg06238570 chr21:40685208 BRWD1 -0.57 -9.38 -0.45 9.26e-19 Cognitive function; LIHC cis rs1757171 0.542 rs1757186 chr6:37484111 A/G cg08126542 chr6:37504118 NA -0.36 -6.18 -0.32 1.86e-9 Cognitive performance; LIHC cis rs2180341 0.960 rs9401952 chr6:127677027 A/C cg27446573 chr6:127587934 RNF146 1.07 16.73 0.67 2.44e-46 Breast cancer; LIHC cis rs7927592 0.763 rs10896351 chr11:68386896 G/A cg16797656 chr11:68205561 LRP5 0.51 8.88 0.43 3.88e-17 Total body bone mineral density; LIHC cis rs4665809 0.549 rs72809635 chr2:26411674 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.11 13.28 0.58 1e-32 Gut microbiome composition (summer); LIHC cis rs67311347 1.000 rs6795475 chr3:40489281 A/G cg09455208 chr3:40491958 NA 0.36 7.39 0.37 1.14e-12 Renal cell carcinoma; LIHC cis rs918629 0.798 rs3777170 chr5:95284340 T/C cg10483112 chr5:95245456 ELL2 -0.36 -6.25 -0.32 1.24e-9 IgG glycosylation; LIHC cis rs2153535 0.580 rs9392224 chr6:8472614 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs9303401 0.573 rs35104446 chr17:57180234 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.57 0.56 4.75e-30 Cognitive test performance; LIHC cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg11301795 chr4:187892539 NA -0.29 -7.65 -0.38 2.13e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.929 rs2280548 chr7:1976667 G/T cg04267008 chr7:1944627 MAD1L1 -0.65 -10.38 -0.49 4e-22 Bipolar disorder and schizophrenia; LIHC cis rs1790761 0.658 rs684928 chr11:67329742 G/A cg21734168 chr11:67353974 GSTP1 -0.27 -6.76 -0.34 6.08e-11 Mean corpuscular volume; LIHC cis rs7551222 0.646 rs1398148 chr1:204458328 C/G cg20240347 chr1:204465584 NA -0.32 -6.69 -0.34 9e-11 Schizophrenia; LIHC cis rs17253792 0.822 rs77741349 chr14:56097462 C/T cg01858014 chr14:56050164 KTN1 -0.72 -6.88 -0.35 2.92e-11 Putamen volume; LIHC cis rs10193935 0.901 rs10200353 chr2:42509554 A/G cg27598129 chr2:42591480 NA -0.7 -10.73 -0.5 2.38e-23 Colonoscopy-negative controls vs population controls; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07920148 chr11:33397821 NA -0.4 -6.06 -0.31 3.54e-9 Pancreatic cancer; LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.99 20.47 0.74 2.35e-61 Height; LIHC cis rs7208859 0.623 rs11650982 chr17:29129955 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.906 rs28447218 chr8:58170813 T/G cg02290350 chr8:58132656 NA 0.41 8.54 0.42 4.46e-16 Developmental language disorder (linguistic errors); LIHC cis rs17401966 0.838 rs7553935 chr1:10375179 G/A cg19773385 chr1:10388646 KIF1B -0.4 -7.29 -0.37 2.23e-12 Hepatocellular carcinoma; LIHC cis rs7584330 0.554 rs7571100 chr2:238435305 G/T cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.41e-9 Prostate cancer; LIHC cis rs7572733 0.555 rs2341778 chr2:198776546 G/A cg03934865 chr2:198174659 NA -0.46 -6.7 -0.34 8.85e-11 Dermatomyositis; LIHC cis rs7772486 0.686 rs2142983 chr6:146069701 G/C cg23711669 chr6:146136114 FBXO30 -0.64 -11.6 -0.53 1.84e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs72627123 0.531 rs79328555 chr14:74588572 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.87 8.43 0.41 1.01e-15 Morning vs. evening chronotype; LIHC cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg09323728 chr8:95962352 TP53INP1 -0.27 -6.03 -0.31 4.25e-9 Type 2 diabetes; LIHC cis rs2576037 0.901 rs2060416 chr18:44576240 G/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.48 -7.16 -0.36 4.93e-12 Personality dimensions; LIHC cis rs9814567 0.806 rs4074523 chr3:134325657 T/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.41 -5.85 -0.3 1.13e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1215050 0.740 rs804051 chr4:98935935 A/T cg05340658 chr4:99064831 C4orf37 -0.4 -6.19 -0.32 1.7e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9581857 0.685 rs9319369 chr13:28042323 A/T cg22138327 chr13:27999177 GTF3A 0.76 6.26 0.32 1.17e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs11105298 0.891 rs10858909 chr12:89935387 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.29 -0.37 2.22e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs903552 0.935 rs4965387 chr15:102003209 G/A cg25677261 chr15:102009856 PCSK6 -0.45 -6.23 -0.32 1.35e-9 Diabetic kidney disease; LIHC cis rs9649465 1.000 rs13225220 chr7:123371026 C/A cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.25e-15 Migraine; LIHC cis rs7618501 0.521 rs3733134 chr3:49939503 C/T cg24110177 chr3:50126178 RBM5 -0.55 -8.62 -0.42 2.56e-16 Intelligence (multi-trait analysis); LIHC cis rs35955747 0.934 rs131200 chr22:31703272 T/C cg22777020 chr22:31556080 RNF185 0.51 5.87 0.3 1.01e-8 Neutrophil count;Sum basophil neutrophil counts; LIHC trans rs7613875 0.600 rs2624826 chr3:50155468 T/G cg21659725 chr3:3221576 CRBN -0.53 -7.89 -0.39 4.26e-14 Body mass index; LIHC cis rs422249 0.727 rs174606 chr11:61626973 G/T cg27386326 chr11:61587980 NA 0.37 6.83 0.35 3.87e-11 Trans fatty acid levels; LIHC cis rs9393692 0.905 rs9357004 chr6:26303319 A/G cg05868516 chr6:26286170 HIST1H4H 0.45 6.98 0.35 1.57e-11 Educational attainment; LIHC cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.0 0.58 1.11e-31 Prudent dietary pattern; LIHC cis rs1475718 0.526 rs10785875 chr9:137122570 C/T cg21243944 chr9:137118148 NA -0.42 -5.92 -0.3 7.86e-9 Immature fraction of reticulocytes;Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs9818758 0.607 rs9837625 chr3:49215966 C/T cg00383909 chr3:49044727 WDR6 0.89 7.23 0.36 3.19e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7412746 0.658 rs7528773 chr1:150915875 G/A cg18016565 chr1:150552671 MCL1 0.52 9.86 0.47 2.31e-20 Melanoma; LIHC cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg00106254 chr7:1943704 MAD1L1 -0.48 -7.88 -0.39 4.52e-14 Bipolar disorder and schizophrenia; LIHC cis rs55665837 1.000 rs34980103 chr11:14512885 C/T cg19336497 chr11:14380999 RRAS2 -0.45 -8.22 -0.41 4.37e-15 Vitamin D levels; LIHC cis rs4561483 0.582 rs3850997 chr16:12043512 G/T cg08843971 chr16:11963173 GSPT1 -0.31 -6.35 -0.32 6.95e-10 Testicular germ cell tumor; LIHC cis rs7707921 0.667 rs111549985 chr5:81268070 C/G cg15871215 chr5:81402204 ATG10 -0.61 -5.84 -0.3 1.2e-8 Breast cancer; LIHC cis rs734999 0.566 rs4648563 chr1:2536002 C/G cg18854424 chr1:2615690 NA 0.31 6.83 0.35 3.91e-11 Ulcerative colitis; LIHC cis rs10193935 0.901 rs1044562 chr2:42516884 C/G cg27598129 chr2:42591480 NA -0.71 -11.02 -0.51 2.18e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs6570726 0.846 rs453834 chr6:145886261 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.62 0.53 1.55e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9549328 0.800 rs9549617 chr13:113628070 C/A cg18289306 chr13:113640169 MCF2L 0.41 6.37 0.33 6.11e-10 Systolic blood pressure; LIHC cis rs8114671 0.562 rs4911161 chr20:33402231 C/T cg07148914 chr20:33460835 GGT7 0.59 8.83 0.43 5.49e-17 Height; LIHC cis rs4803468 1.000 rs3810175 chr19:41904396 C/T cg14132834 chr19:41945861 ATP5SL 0.42 6.34 0.32 7.3e-10 Height; LIHC cis rs2576037 0.583 rs4890343 chr18:44540969 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.87 -0.3 1.02e-8 Personality dimensions; LIHC cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg16060761 chr17:80687452 NA 0.48 7.26 0.37 2.58e-12 Glycated hemoglobin levels; LIHC cis rs903552 1.000 rs12908406 chr15:102004046 C/T cg25677261 chr15:102009856 PCSK6 -0.48 -6.53 -0.33 2.44e-10 Diabetic kidney disease; LIHC cis rs1419980 0.673 rs2377086 chr12:7753798 C/T cg14906510 chr12:7781169 NA 0.48 7.45 0.37 7.73e-13 HDL cholesterol levels; LIHC cis rs172166 0.694 rs1150666 chr6:28123928 T/C cg23485639 chr6:28045615 ZNF165 0.38 5.96 0.31 6.31e-9 Cardiac Troponin-T levels; LIHC cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs12477438 0.520 rs4851188 chr2:99745898 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 9.9 0.47 1.76e-20 Chronic sinus infection; LIHC cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg03806693 chr22:41940476 POLR3H -1.07 -12.47 -0.56 1.15e-29 Vitiligo; LIHC cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg02187348 chr16:89574699 SPG7 -0.53 -8.22 -0.41 4.34e-15 Multiple myeloma (IgH translocation); LIHC cis rs7618501 0.602 rs9311446 chr3:50092226 G/A cg24110177 chr3:50126178 RBM5 0.5 7.99 0.4 2.03e-14 Intelligence (multi-trait analysis); LIHC cis rs62458065 0.713 rs3801329 chr7:32496956 A/C cg06627557 chr7:32535165 LSM5;AVL9 -0.61 -5.92 -0.3 7.95e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs8180040 0.726 rs9843075 chr3:47195630 A/G cg27129171 chr3:47204927 SETD2 0.57 8.94 0.44 2.45e-17 Colorectal cancer; LIHC cis rs12971120 0.891 rs2278159 chr18:72178161 T/C cg25817165 chr18:72167213 CNDP2 -0.71 -12.24 -0.55 8.01e-29 Refractive error; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.48 0.37 6.51e-13 Prudent dietary pattern; LIHC cis rs4423214 1.000 rs4944959 chr11:71168234 C/T cg05163923 chr11:71159392 DHCR7 -0.87 -13.44 -0.59 2.43e-33 Vitamin D levels; LIHC cis rs7927771 0.832 rs11039212 chr11:47393303 A/T cg20135002 chr11:47629003 NA 0.5 8.43 0.41 9.57e-16 Subjective well-being; LIHC cis rs546131 0.928 rs546521 chr11:34824773 G/C cg11058730 chr11:34937778 PDHX;APIP 0.59 8.87 0.43 4.15e-17 Lung disease severity in cystic fibrosis; LIHC cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg08219700 chr8:58056026 NA 0.46 5.8 0.3 1.48e-8 Developmental language disorder (linguistic errors); LIHC cis rs17539620 0.624 rs74551216 chr6:154840524 T/C cg20019720 chr6:154832845 CNKSR3 0.4 6.1 0.31 2.89e-9 Lipoprotein (a) levels; LIHC cis rs6964587 1.000 rs13224513 chr7:91601465 G/A cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1e-57 Breast cancer; LIHC cis rs6748734 1.000 rs6751693 chr2:241837332 T/C cg04034577 chr2:241836375 C2orf54 -0.41 -8.13 -0.4 7.71e-15 Urinary metabolites; LIHC cis rs748404 0.578 rs507178 chr15:43610135 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.59 10.51 0.49 1.42e-22 Lung cancer; LIHC cis rs796364 0.906 rs281784 chr2:200749749 T/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.73 8.52 0.42 5.06e-16 Schizophrenia; LIHC cis rs8077889 0.703 rs231532 chr17:41945769 C/T cg26893861 chr17:41843967 DUSP3 -0.73 -7.35 -0.37 1.45e-12 Triglycerides; LIHC cis rs473651 0.837 rs563458 chr2:239345613 T/A cg21699342 chr2:239360505 ASB1 0.37 7.03 0.36 1.13e-11 Multiple system atrophy; LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg24209194 chr3:40518798 ZNF619 -0.59 -8.73 -0.43 1.12e-16 Renal cell carcinoma; LIHC cis rs7223966 1.000 rs11079509 chr17:61762148 G/T cg05941027 chr17:61774174 LIMD2 0.33 6.19 0.32 1.68e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9457247 1.000 rs386548 chr6:167385533 A/T cg12798992 chr6:167411361 FGFR1OP -0.59 -9.83 -0.47 3.11e-20 Crohn's disease; LIHC cis rs7927592 0.913 rs3824850 chr11:68341873 A/G cg01657329 chr11:68192670 LRP5 -0.48 -6.22 -0.32 1.46e-9 Total body bone mineral density; LIHC trans rs60843830 1.000 rs55936726 chr2:258210 T/C cg11347411 chr7:150020925 ACTR3C;LRRC61 0.68 9.71 0.46 7.5599999999999994e-20 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs3814244 0.528 rs7962511 chr12:68396634 C/G cg15249341 chr12:68405565 NA -0.33 -6.35 -0.32 6.73e-10 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs2439831 0.850 rs3816792 chr15:44116986 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.59 -8.61 -0.42 2.79e-16 Lung cancer in ever smokers; LIHC cis rs924607 0.931 rs1709556 chr5:637058 A/G cg24163568 chr5:669837 TPPP 0.39 8.2 0.41 5.01e-15 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2412488 0.893 rs6840343 chr4:54359680 C/T cg22241045 chr4:54363911 LNX1 0.4 6.54 0.33 2.24e-10 DNA methylation (variation); LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg11070056 chr1:107600091 PRMT6 -0.63 -10.46 -0.49 2.05e-22 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg00101154 chr16:420108 MRPL28 -0.7 -11.64 -0.53 1.3e-26 Bone mineral density (spine);Bone mineral density; LIHC cis rs7412746 0.566 rs11204743 chr1:150890406 A/T cg18016565 chr1:150552671 MCL1 0.52 9.74 0.47 6.21e-20 Melanoma; LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg14828511 chr1:107599125 PRMT6 0.42 6.07 0.31 3.32e-9 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs72766638 1.000 rs72766638 chr9:136931778 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.59 -6.57 -0.33 1.87e-10 Mosquito bite size; LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg16132339 chr22:24313637 DDTL;DDT 0.71 13.12 0.58 3.78e-32 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg03806693 chr22:41940476 POLR3H -1.08 -12.34 -0.55 3.55e-29 Vitiligo; LIHC cis rs8067545 0.750 rs1421174 chr17:19950190 G/T cg13482628 chr17:19912719 NA 0.5 8.23 0.41 3.93e-15 Schizophrenia; LIHC cis rs7617773 0.817 rs13072018 chr3:48320332 G/A cg11946769 chr3:48343235 NME6 0.91 11.36 0.52 1.36e-25 Coronary artery disease; LIHC cis rs7224685 0.569 rs34357603 chr17:4008760 G/A cg09695851 chr17:3907499 NA 0.6 6.91 0.35 2.33e-11 Type 2 diabetes; LIHC cis rs1003719 0.715 rs2835653 chr21:38558636 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.72 -0.5 2.65e-23 Eye color traits; LIHC cis rs11758351 1.000 rs77957229 chr6:26185226 A/G cg06951627 chr6:26196580 NA 0.53 5.94 0.31 7.2e-9 Gout;Renal underexcretion gout; LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.4 0.37 1.05e-12 Prudent dietary pattern; LIHC cis rs34779708 0.931 rs7923172 chr10:35309367 G/A cg03585969 chr10:35415529 CREM 0.84 12.66 0.56 2.25e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg11890956 chr21:40555474 PSMG1 -0.52 -8.6 -0.42 2.94e-16 Cognitive function; LIHC trans rs13067260 1.000 rs16835220 chr3:123960246 C/T cg16386950 chr1:201616077 NAV1 0.52 6.33 0.32 7.5e-10 PR interval in Tripanosoma cruzi seropositivity; LIHC trans rs11098499 0.954 rs2306455 chr4:120421969 G/A cg25214090 chr10:38739885 LOC399744 0.57 9.36 0.45 1.13e-18 Corneal astigmatism; LIHC cis rs12220238 0.915 rs11001027 chr10:76152655 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.76 0.3 1.85e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs539514 0.690 rs34545980 chr13:76309637 C/A cg04757411 chr13:76259545 LMO7 -0.44 -7.89 -0.39 4.13e-14 Type 1 diabetes; LIHC cis rs2404602 0.735 rs56246286 chr15:76690731 C/T cg23625390 chr15:77176239 SCAPER -0.48 -8.04 -0.4 1.5e-14 Blood metabolite levels; LIHC cis rs7312774 0.748 rs7966019 chr12:107297502 G/T cg16260113 chr12:107380972 MTERFD3 0.8 10.49 0.49 1.67e-22 Severe influenza A (H1N1) infection; LIHC cis rs11030122 0.661 rs963998 chr11:4062803 A/G cg18678763 chr11:4115507 RRM1 -0.57 -8.46 -0.42 8.06e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs1670533 1.000 rs6599279 chr4:1058833 G/A cg27284194 chr4:1044797 NA 0.59 8.79 0.43 7.18e-17 Recombination rate (females); LIHC cis rs2180341 0.842 rs9375492 chr6:127545492 C/T cg24812749 chr6:127587940 RNF146 -1.03 -14.31 -0.61 9.75e-37 Breast cancer; LIHC cis rs7737355 0.898 rs4706030 chr5:130957486 A/G cg06307176 chr5:131281290 NA 0.4 5.78 0.3 1.73e-8 Life satisfaction; LIHC cis rs7617773 0.779 rs1045482 chr3:48312229 A/G cg11946769 chr3:48343235 NME6 0.64 8.82 0.43 5.9e-17 Coronary artery disease; LIHC cis rs2439831 0.850 rs28684672 chr15:44107662 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.42 0.33 4.42e-10 Lung cancer in ever smokers; LIHC cis rs8062405 1.000 rs2008514 chr16:28825605 A/G cg16576597 chr16:28551801 NUPR1 -0.36 -6.02 -0.31 4.39e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4819052 0.819 rs7279136 chr21:46692287 C/T cg22633049 chr21:46681294 NA -0.38 -6.5 -0.33 2.79e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1008375 1.000 rs17507481 chr4:17620066 A/G cg02297831 chr4:17616191 MED28 0.52 8.0 0.4 1.91e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9486715 0.867 rs11152924 chr6:96877383 A/G cg06623918 chr6:96969491 KIAA0776 0.86 14.92 0.63 4.06e-39 Headache; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs651907 0.557 rs36002990 chr3:101437862 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.45 -0.33 3.81e-10 Colorectal cancer; LIHC trans rs12478296 0.901 rs9653611 chr2:243006956 C/G cg01596870 chr19:55963115 NA -0.67 -9.66 -0.46 1.09e-19 Obesity-related traits; LIHC cis rs4663866 1.000 rs13033501 chr2:239181860 G/A cg16914508 chr2:239161102 PER2 0.8 5.9 0.3 8.86e-9 Irritable bowel syndrome; LIHC cis rs9952991 0.883 rs2847260 chr18:12775591 C/T cg23598886 chr18:12777645 NA 0.47 6.44 0.33 4.01e-10 Inflammatory skin disease; LIHC cis rs6456156 0.586 rs12529876 chr6:167461501 G/A cg07741184 chr6:167504864 NA 0.29 6.93 0.35 2.04e-11 Primary biliary cholangitis; LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs8180040 0.726 rs1869871 chr3:47023948 C/T cg16586182 chr3:47516702 SCAP -0.44 -7.73 -0.39 1.17e-13 Colorectal cancer; LIHC cis rs4819052 0.679 rs2255761 chr21:46683622 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.59 0.38 3.02e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs694739 0.628 rs538147 chr11:64129722 G/A cg23796481 chr11:64053134 BAD;GPR137 0.46 6.2 0.32 1.63e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs10193935 0.901 rs10174872 chr2:42459807 T/G cg27598129 chr2:42591480 NA -0.73 -10.87 -0.51 7.92e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.89 0.3 9.48e-9 Aortic root size; LIHC cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg08888203 chr3:10149979 C3orf24 0.57 6.76 0.34 5.85e-11 Alzheimer's disease; LIHC cis rs12549902 0.800 rs7825494 chr8:41507350 C/T cg21772509 chr8:41503840 NKX6-3 0.39 6.42 0.33 4.58e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs3820500 0.543 rs34368125 chr1:118026538 C/A cg20383390 chr1:117909022 MAN1A2 -0.47 -6.03 -0.31 4.32e-9 Pneumonia; LIHC cis rs1018836 0.828 rs2105968 chr8:91591825 A/G cg16814680 chr8:91681699 NA -0.54 -8.64 -0.42 2.16e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs72781680 0.752 rs72796119 chr2:23917179 C/T cg08917208 chr2:24149416 ATAD2B 0.97 8.04 0.4 1.44e-14 Lymphocyte counts; LIHC cis rs9733 0.596 rs2275236 chr1:150669952 A/G cg17724175 chr1:150552817 MCL1 -0.49 -9.73 -0.47 6.48e-20 Tonsillectomy; LIHC cis rs941408 0.515 rs1640265 chr19:2784405 C/T cg06609049 chr19:2785107 THOP1 0.78 12.43 0.56 1.61e-29 Total cholesterol levels; LIHC cis rs941873 0.868 rs2145998 chr10:81121696 T/A cg11057378 chr10:81107060 PPIF 0.37 6.01 0.31 4.75e-9 Height; LIHC cis rs34779708 0.677 rs112355105 chr10:35550294 A/T cg03585969 chr10:35415529 CREM 0.74 10.66 0.5 4.27e-23 Inflammatory bowel disease;Crohn's disease; LIHC trans rs561341 1.000 rs8073186 chr17:30244956 T/C cg20587970 chr11:113659929 NA -0.63 -7.29 -0.37 2.19e-12 Hip circumference adjusted for BMI; LIHC cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -10.85 -0.51 8.78e-24 Platelet count; LIHC cis rs10484885 0.878 rs72921934 chr6:90579464 T/A cg13799429 chr6:90582589 CASP8AP2 -0.69 -6.54 -0.33 2.29e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9326248 0.953 rs488962 chr11:117072525 C/T cg26566898 chr11:117069891 TAGLN -0.48 -7.49 -0.38 5.84e-13 Blood protein levels; LIHC cis rs3809566 1.000 rs4775610 chr15:63332057 C/T cg12160578 chr15:63334699 TPM1 0.6 8.63 0.42 2.4e-16 Platelet count; LIHC cis rs7107174 1.000 rs7941617 chr11:78021146 C/T cg02023728 chr11:77925099 USP35 0.48 9.15 0.44 5.44e-18 Testicular germ cell tumor; LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.59 -8.59 -0.42 3.1e-16 Lymphocyte counts; LIHC cis rs9902453 0.845 rs58606097 chr17:28020379 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.81 0.54 3.07e-27 Coffee consumption (cups per day); LIHC cis rs10493773 0.609 rs12058974 chr1:86192235 T/A cg17807903 chr1:86174739 ZNHIT6 -0.6 -11.76 -0.54 4.99e-27 Urate levels in overweight individuals; LIHC cis rs2404602 0.735 rs11637490 chr15:76759565 A/G cg23625390 chr15:77176239 SCAPER -0.51 -8.54 -0.42 4.46e-16 Blood metabolite levels; LIHC cis rs769267 0.965 rs1010207 chr19:19416045 T/C cg03709012 chr19:19516395 GATAD2A 0.93 15.51 0.64 1.79e-41 Tonsillectomy; LIHC cis rs13223928 0.658 rs67519056 chr7:3157176 G/C cg19214707 chr7:3157722 NA -0.45 -8.46 -0.42 7.99e-16 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs17401966 0.809 rs12406943 chr1:10308545 T/C cg19773385 chr1:10388646 KIF1B -0.4 -7.33 -0.37 1.65e-12 Hepatocellular carcinoma; LIHC trans rs56011263 0.687 rs4690186 chr4:703607 G/A cg12575136 chr18:32820987 ZNF397 0.48 7.04 0.36 1.06e-11 White blood cell count; LIHC cis rs6089584 0.606 rs7270666 chr20:60577598 C/T cg06108461 chr20:60628389 TAF4 -0.53 -7.28 -0.37 2.32e-12 Body mass index; LIHC cis rs250677 0.687 rs10040624 chr5:148437579 A/G cg18129178 chr5:148520854 ABLIM3 -0.48 -7.48 -0.38 6.18e-13 Breast cancer; LIHC cis rs80282103 0.618 rs74120451 chr10:1126866 T/C cg18964960 chr10:1102726 WDR37 0.66 5.9 0.3 8.54e-9 Glomerular filtration rate (creatinine); LIHC cis rs7086627 0.515 rs11202959 chr10:82209672 A/G cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs9814567 1.000 rs7630874 chr3:134293291 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.86 0.3 1.08e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1559088 0.947 rs7256182 chr19:33558591 G/A cg27124370 chr19:33622961 WDR88 0.47 7.09 0.36 7.77e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs72772090 0.710 rs17479052 chr5:96065636 A/G cg17330273 chr5:96107758 CAST;ERAP1 -0.65 -7.26 -0.37 2.69e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs644799 0.930 rs587123 chr11:95560539 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7520050 0.966 rs11211208 chr1:46334256 A/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 5.97 0.31 5.82e-9 Red blood cell count;Reticulocyte count; LIHC cis rs9393692 0.905 rs7761298 chr6:26278436 C/T cg00631329 chr6:26305371 NA -0.43 -7.25 -0.36 2.88e-12 Educational attainment; LIHC cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs61677309 1.000 rs12576100 chr11:118158281 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC trans rs2727020 0.619 rs1164665 chr11:49295630 T/C cg15704280 chr7:45808275 SEPT13 0.76 10.9 0.51 6.19e-24 Coronary artery disease; LIHC cis rs3096299 0.967 rs28575874 chr16:89469890 C/T cg08822215 chr16:89438651 ANKRD11 -0.43 -6.69 -0.34 9.36e-11 Multiple myeloma (IgH translocation); LIHC cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg27286337 chr10:134555280 INPP5A 0.81 12.06 0.55 3.88e-28 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12887734 0.566 rs8548 chr14:104199580 A/C cg08213375 chr14:104286397 PPP1R13B 0.5 8.43 0.41 9.97e-16 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs4803468 1.000 rs284656 chr19:41929251 T/C cg09537434 chr19:41945824 ATP5SL -1.03 -21.53 -0.76 1.36e-65 Height; LIHC cis rs11583043 1.000 rs6675353 chr1:101459625 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.62 8.44 0.42 9.17e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9911578 0.967 rs57869245 chr17:57106630 A/G cg05425664 chr17:57184151 TRIM37 0.58 8.71 0.43 1.36e-16 Intelligence (multi-trait analysis); LIHC cis rs6951245 1.000 rs2363286 chr7:1091625 A/G cg24642844 chr7:1081250 C7orf50 -0.87 -8.64 -0.42 2.2e-16 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs801193 1.000 rs2707836 chr7:66160435 A/C cg14393609 chr7:65229607 NA 0.38 5.91 0.3 8.22e-9 Aortic root size; LIHC cis rs875971 0.862 rs2420611 chr7:65999320 A/G cg18252515 chr7:66147081 NA -0.46 -6.82 -0.35 4.19e-11 Aortic root size; LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs644799 1.000 rs481630 chr11:95582447 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.88 16.24 0.66 2.26e-44 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11098499 0.874 rs17839089 chr4:120111069 A/G cg09307838 chr4:120376055 NA 0.52 7.68 0.38 1.71e-13 Corneal astigmatism; LIHC cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg07424592 chr7:64974309 NA -0.8 -9.32 -0.45 1.44e-18 Diabetic kidney disease; LIHC cis rs11030122 0.592 rs4910880 chr11:4084630 C/G cg18678763 chr11:4115507 RRM1 -0.58 -8.7 -0.43 1.38e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs739401 0.611 rs7109088 chr11:3027485 G/T cg20651018 chr11:3035856 CARS -0.36 -6.25 -0.32 1.22e-9 Longevity; LIHC cis rs7264396 0.635 rs6058344 chr20:34475038 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.7 -0.5 3.09e-23 Total cholesterol levels; LIHC cis rs9393692 0.905 rs6940237 chr6:26282322 T/C cg05868516 chr6:26286170 HIST1H4H 0.41 6.25 0.32 1.21e-9 Educational attainment; LIHC cis rs12451471 0.667 rs12942002 chr17:78101629 C/G cg24585782 chr17:78113791 EIF4A3 -0.44 -5.85 -0.3 1.12e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04578738 chr17:34136331 TAF15 0.42 6.11 0.31 2.64e-9 Pancreatic cancer; LIHC cis rs950169 0.920 rs2135551 chr15:84707851 A/G cg17507749 chr15:85114479 UBE2QP1 0.74 7.48 0.38 6.24e-13 Schizophrenia; LIHC cis rs10508774 1.000 rs10160127 chr10:32953719 T/C cg01819863 chr10:32635814 EPC1 0.61 5.72 0.3 2.33e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9733 0.596 rs6692960 chr1:150695965 G/A cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs16854884 0.657 rs35796781 chr3:143731662 T/C cg06585982 chr3:143692056 C3orf58 0.48 6.01 0.31 4.66e-9 Economic and political preferences (feminism/equality); LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg11446345 chr19:17445677 ANO8 0.38 6.07 0.31 3.32e-9 Metabolic traits; LIHC cis rs10508774 0.810 rs56102114 chr10:32748855 C/T cg01819863 chr10:32635814 EPC1 0.61 5.81 0.3 1.45e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2717559 0.522 rs35816096 chr8:143884938 C/T cg07661805 chr8:143867942 LY6D -0.32 -6.86 -0.35 3.16e-11 Urinary tract infection frequency; LIHC cis rs9916302 0.904 rs4357971 chr17:37717280 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.46 -0.59 1.92e-33 Glomerular filtration rate (creatinine); LIHC cis rs9649213 0.593 rs7803372 chr7:97992257 A/G cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.91 -0.3 8.06e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs12950390 0.853 rs28589850 chr17:45855713 A/G cg03474202 chr17:45855739 NA -0.34 -5.9 -0.3 8.75e-9 IgG glycosylation; LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs769267 0.896 rs10405625 chr19:19579046 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.0 0.4 1.99e-14 Tonsillectomy; LIHC cis rs7172677 0.768 rs72730585 chr15:75353906 A/G cg17294928 chr15:75287854 SCAMP5 0.47 6.64 0.34 1.25e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs4650994 0.593 rs12033086 chr1:178540925 C/T cg05350800 chr1:178550844 NA -0.35 -7.7 -0.38 1.49e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs6754311 0.731 rs2236783 chr2:136594158 G/A cg25344623 chr2:136566232 LCT 0.4 8.07 0.4 1.2e-14 Mosquito bite size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02973843 chr8:42268727 NA -0.44 -6.41 -0.33 4.87e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6504950 0.800 rs12952253 chr17:53005716 A/G cg10237252 chr17:52977213 TOM1L1 -0.35 -6.15 -0.32 2.15e-9 Breast cancer; LIHC cis rs4478858 0.775 rs6701861 chr1:31708125 A/C cg00250761 chr1:31883323 NA -0.26 -6.04 -0.31 4.05e-9 Alcohol dependence; LIHC cis rs2522056 1.000 rs2522056 chr5:131801726 C/T cg24060327 chr5:131705240 SLC22A5 0.55 7.32 0.37 1.77e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs9818758 0.607 rs73074866 chr3:49626666 C/T cg00383909 chr3:49044727 WDR6 0.82 6.42 0.33 4.69e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg03346523 chr11:32951061 QSER1 -0.3 -6.8 -0.35 4.62e-11 Calcium levels; LIHC cis rs12477438 0.520 rs11123762 chr2:99727789 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.53 0.64 1.5e-41 Chronic sinus infection; LIHC cis rs2204008 0.720 rs11181343 chr12:38323616 G/T cg26384229 chr12:38710491 ALG10B 0.6 8.19 0.4 5.21e-15 Bladder cancer; LIHC cis rs9486719 1.000 rs4078038 chr6:96904366 A/G cg06623918 chr6:96969491 KIAA0776 -0.7 -7.16 -0.36 4.89e-12 Migraine;Coronary artery disease; LIHC cis rs8038465 0.592 rs1542579 chr15:73935897 A/G cg15420318 chr15:73925796 NPTN 0.49 7.55 0.38 4.06e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg14343924 chr8:8086146 FLJ10661 -0.42 -5.94 -0.31 6.95e-9 Mood instability; LIHC cis rs7552404 0.727 rs1146653 chr1:76280438 A/G cg03433033 chr1:76189801 ACADM 0.55 6.89 0.35 2.76e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs35306767 0.903 rs4522091 chr10:874116 G/T cg26597838 chr10:835615 NA 1.19 13.58 0.59 7.02e-34 Eosinophil percentage of granulocytes; LIHC cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg03351412 chr1:154909251 PMVK 0.7 10.46 0.49 2.17e-22 Prostate cancer; LIHC cis rs708547 0.647 rs12621 chr4:57897570 G/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.48 7.06 0.36 9.42e-12 Response to bleomycin (chromatid breaks); LIHC cis rs644799 0.540 rs10831419 chr11:95478037 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.79 12.29 0.55 5.46e-29 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2278034 0.578 rs881753 chr3:195606770 C/T cg12923728 chr3:195709715 SDHAP1 0.43 5.95 0.31 6.57e-9 Bronchopulmonary dysplasia; LIHC cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 11.49 0.53 4.74e-26 Platelet count; LIHC cis rs2549003 1.000 rs7701588 chr5:131819970 T/C cg02551604 chr5:131831745 NA -0.44 -6.54 -0.33 2.24e-10 Asthma (sex interaction); LIHC cis rs1443512 0.755 rs1373160 chr12:54340383 A/G cg12374095 chr12:54320830 NA 0.4 5.74 0.3 2.1e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs3768617 0.811 rs4366285 chr1:183013672 T/G ch.1.3577855R chr1:183094577 LAMC1 0.47 7.48 0.37 6.42e-13 Fuchs's corneal dystrophy; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg06558623 chr16:89946397 TCF25 0.95 14.44 0.62 3.05e-37 Skin colour saturation; LIHC cis rs9926296 0.585 rs8058009 chr16:89856439 G/C cg08547343 chr16:90038815 CENPBD1;AFG3L1 -0.72 -7.59 -0.38 3.13e-13 Vitiligo; LIHC cis rs4746818 1.000 rs10823301 chr10:70885875 G/A cg11621586 chr10:70884670 VPS26A 0.88 14.61 0.62 6.47e-38 Left atrial antero-posterior diameter; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09273779 chr9:35605990 TESK1 0.48 7.41 0.37 1.02e-12 Pancreatic cancer; LIHC cis rs9733 0.566 rs11204675 chr1:150570985 A/C cg13175981 chr1:150552382 MCL1 0.63 9.63 0.46 1.46e-19 Tonsillectomy; LIHC cis rs8177253 0.965 rs4854760 chr3:133498741 C/T cg12373951 chr3:133503437 NA -0.65 -11.54 -0.53 2.94e-26 Iron status biomarkers; LIHC cis rs7666738 0.830 rs28615340 chr4:98896922 T/C cg05340658 chr4:99064831 C4orf37 0.65 11.71 0.54 7.16e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs1707322 0.717 rs3014249 chr1:46079493 A/G cg06784218 chr1:46089804 CCDC17 -0.41 -7.19 -0.36 4.16e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.4 0.37 1.08e-12 Electroencephalogram traits; LIHC trans rs208520 0.874 rs208515 chr6:66945749 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.69 -7.6 -0.38 2.95e-13 Exhaled nitric oxide output; LIHC cis rs4423214 1.000 rs732934 chr11:71186476 G/A cg05163923 chr11:71159392 DHCR7 0.89 13.34 0.59 5.63e-33 Vitamin D levels; LIHC cis rs4808199 0.901 rs12973258 chr19:19488718 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.44 6.26 0.32 1.14e-9 Nonalcoholic fatty liver disease; LIHC cis rs1003719 0.788 rs2835574 chr21:38455324 C/A cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.06 0.55 3.76e-28 Eye color traits; LIHC cis rs12986413 1.000 rs12982593 chr19:2175891 C/A cg09261902 chr19:2140048 AP3D1 0.37 6.38 0.33 5.85e-10 Height; LIHC cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.68 -11.21 -0.52 4.89e-25 Colorectal cancer; LIHC cis rs9911578 1.000 rs2643119 chr17:56827760 G/T cg05425664 chr17:57184151 TRIM37 -0.57 -8.5 -0.42 5.75e-16 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.720 rs162393 chr21:44942692 G/A cg01579765 chr21:45077557 HSF2BP -0.34 -6.22 -0.32 1.48e-9 Mean corpuscular volume; LIHC cis rs727563 0.580 rs202626 chr22:41847190 C/A cg06634786 chr22:41940651 POLR3H 0.8 9.2 0.45 3.64e-18 Crohn's disease;Inflammatory bowel disease; LIHC cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg26338869 chr17:61819248 STRADA 0.5 6.66 0.34 1.1e-10 Height; LIHC cis rs7918232 0.607 rs1755401 chr10:27405763 A/C cg14442939 chr10:27389572 ANKRD26 0.74 6.08 0.31 3.21e-9 Breast cancer; LIHC cis rs2153535 0.580 rs915352 chr6:8442766 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11708118 chr12:6862968 MLF2 0.51 6.54 0.33 2.2e-10 Lung function (FEV1/FVC); LIHC cis rs1799949 0.965 rs9911630 chr17:41188342 A/G cg23758822 chr17:41437982 NA 0.9 16.48 0.67 2.42e-45 Menopause (age at onset); LIHC cis rs7116495 1.000 rs4944242 chr11:71667141 G/T cg26138937 chr11:71823887 C11orf51 -0.81 -7.96 -0.4 2.64e-14 Severe influenza A (H1N1) infection; LIHC cis rs6964587 0.626 rs2106745 chr7:91506635 C/T cg17063962 chr7:91808500 NA -0.61 -11.04 -0.51 1.96e-24 Breast cancer; LIHC cis rs61677309 0.929 rs58983315 chr11:118167759 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.44 0.33 4.14e-10 Lung cancer in ever smokers; LIHC cis rs782590 0.818 rs2627782 chr2:55825352 A/G cg18811423 chr2:55921094 PNPT1 0.79 11.65 0.53 1.22e-26 Metabolic syndrome; LIHC cis rs1046896 0.739 rs2379358 chr17:80741612 G/A cg08200770 chr17:80723486 TBCD -0.35 -5.81 -0.3 1.42e-8 Glycated hemoglobin levels; LIHC cis rs6942756 1.000 rs6467235 chr7:128939150 A/G cg02491457 chr7:128862824 NA 0.57 6.44 0.33 3.99e-10 White matter hyperintensity burden; LIHC cis rs2050392 0.767 rs2183175 chr10:30699336 A/G cg25182066 chr10:30743637 MAP3K8 0.56 8.8 0.43 6.96e-17 Inflammatory bowel disease; LIHC cis rs8072100 0.840 rs1912482 chr17:45454883 G/A cg08085267 chr17:45401833 C17orf57 -0.55 -8.28 -0.41 2.73e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2991971 0.967 rs937291 chr1:45957039 G/T cg05343316 chr1:45956843 TESK2 -0.42 -6.19 -0.32 1.71e-9 High light scatter reticulocyte count; LIHC cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg11062466 chr8:58055876 NA 0.51 6.85 0.35 3.53e-11 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.753 rs4732595 chr7:75755139 A/G cg16684958 chr7:75615977 POR 0.51 8.53 0.42 4.98e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4268898 0.662 rs9784114 chr2:24437517 C/T cg06627628 chr2:24431161 ITSN2 -0.73 -9.65 -0.46 1.17e-19 Asthma; LIHC cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg10802521 chr3:52805072 NEK4 -0.44 -7.26 -0.37 2.61e-12 Bipolar disorder; LIHC cis rs208520 0.706 rs851601 chr6:66893853 G/A cg07460842 chr6:66804631 NA -0.76 -8.55 -0.42 4.17e-16 Exhaled nitric oxide output; LIHC cis rs4820539 1.000 rs885963 chr22:23460939 G/T cg21100191 chr22:23484243 RTDR1 0.89 16.04 0.66 1.5e-43 Bone mineral density; LIHC cis rs6450176 0.633 rs617777 chr5:53330440 T/C ch.5.1024479R chr5:53302184 ARL15 -0.76 -13.72 -0.6 1.87e-34 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs644799 0.710 rs12273579 chr11:95524421 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.7 0.57 1.59e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12986413 0.624 rs2159213 chr19:2136102 T/C cg09261902 chr19:2140048 AP3D1 0.4 6.89 0.35 2.75e-11 Height; LIHC cis rs78545713 1.000 rs16891484 chr6:26242930 G/A cg16070018 chr6:26224392 HIST1H3E 0.62 6.9 0.35 2.5e-11 Iron status biomarkers (total iron binding capacity); LIHC cis rs6952407 1 rs6952407 chr7:66045512 A/G cg11764359 chr7:65958608 NA -0.7 -9.69 -0.46 8.55e-20 Cotinine glucuronidation; LIHC cis rs1799949 0.965 rs8071278 chr17:41193910 A/T cg23758822 chr17:41437982 NA 0.96 18.01 0.7 1.72e-51 Menopause (age at onset); LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs870825 0.929 rs72689272 chr4:185592515 T/C cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs6582630 0.519 rs10880576 chr12:38497693 T/C cg26384229 chr12:38710491 ALG10B 0.65 9.07 0.44 9.79e-18 Drug-induced liver injury (flucloxacillin); LIHC cis rs6089584 1.000 rs6089591 chr20:60570548 A/C cg13770153 chr20:60521292 NA -0.35 -6.96 -0.35 1.8e-11 Body mass index; LIHC cis rs3849570 0.961 rs13340130 chr3:81790970 A/T cg07356753 chr3:81810745 GBE1 -0.64 -10.66 -0.5 4.28e-23 Waist circumference;Body mass index; LIHC cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg12751644 chr20:60527061 NA 0.5 8.36 0.41 1.56e-15 Obesity-related traits; LIHC cis rs8044995 0.636 rs9888986 chr16:68297228 G/A cg09835421 chr16:68378352 PRMT7 -0.56 -5.89 -0.3 9.22e-9 Schizophrenia; LIHC cis rs6708331 0.517 rs9989836 chr2:70342727 G/A cg01613454 chr2:70366299 NA 0.38 6.15 0.32 2.18e-9 Obesity-related traits; LIHC cis rs9916302 0.610 rs11078902 chr17:37631883 C/G cg07936489 chr17:37558343 FBXL20 -0.84 -13.43 -0.59 2.61e-33 Glomerular filtration rate (creatinine); LIHC cis rs700651 0.856 rs9288280 chr2:198744324 A/G cg00792783 chr2:198669748 PLCL1 0.49 7.25 0.36 2.83e-12 Intracranial aneurysm; LIHC cis rs7264396 0.635 rs6060656 chr20:34466382 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.6 -0.5 6.95e-23 Total cholesterol levels; LIHC cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg23758822 chr17:41437982 NA -0.94 -17.93 -0.7 3.9e-51 Menopause (age at onset); LIHC cis rs3096299 0.933 rs28608022 chr16:89454292 C/T cg08822215 chr16:89438651 ANKRD11 -0.45 -7.15 -0.36 5.41e-12 Multiple myeloma (IgH translocation); LIHC cis rs67981189 0.593 rs9323557 chr14:71470840 C/T cg15816911 chr14:71606274 NA -0.45 -6.28 -0.32 1.02e-9 Schizophrenia; LIHC cis rs9399135 0.967 rs12526055 chr6:135325918 C/T cg24558204 chr6:135376177 HBS1L 0.4 6.51 0.33 2.6200000000000003e-10 Red blood cell count; LIHC cis rs477895 0.639 rs35858916 chr11:63950529 T/G cg05555928 chr11:63887634 MACROD1 0.51 6.58 0.34 1.81e-10 Mean platelet volume; LIHC cis rs11628318 0.853 rs4906226 chr14:103027359 C/T cg01864069 chr14:103024347 NA -0.58 -9.55 -0.46 2.53e-19 Platelet count; LIHC cis rs473651 0.901 rs563282 chr2:239329736 T/C cg18131467 chr2:239335373 ASB1 0.91 15.17 0.63 4.07e-40 Multiple system atrophy; LIHC trans rs1973993 0.967 rs10875017 chr1:96949526 C/T cg10631902 chr5:14652156 NA 0.29 6.43 0.33 4.41e-10 Weight; LIHC cis rs3806843 0.933 rs2879087 chr5:140188575 G/C cg19875535 chr5:140030758 IK 0.36 5.82 0.3 1.37e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7520050 0.966 rs10890361 chr1:46346234 A/T cg03146154 chr1:46216737 IPP -0.38 -6.13 -0.31 2.47e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11608355 0.515 rs11611012 chr12:109945203 G/A cg05360138 chr12:110035743 NA 0.95 8.99 0.44 1.67e-17 Neuroticism; LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.95 0.57 1.78e-31 Prudent dietary pattern; LIHC cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.8 12.56 0.56 4.96e-30 Total body bone mineral density; LIHC cis rs10792665 0.649 rs10792671 chr11:82728209 A/C cg24227371 chr11:82718527 RAB30 -0.37 -9.31 -0.45 1.61e-18 Obesity-related traits; LIHC cis rs13064411 0.696 rs1552432 chr3:113225660 G/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs8027181 1.000 rs7164727 chr15:73093991 C/T cg25632853 chr15:73088954 NA 0.37 6.25 0.32 1.19e-9 Triglyceride levels; LIHC cis rs11098499 0.863 rs3822195 chr4:120471660 C/T cg09307838 chr4:120376055 NA 0.75 11.43 0.53 7.53e-26 Corneal astigmatism; LIHC cis rs225245 0.782 rs161183 chr17:33919475 G/C cg05299278 chr17:33885742 SLFN14 0.22 6.0 0.31 5.1e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg27166718 chr6:118880109 PLN;C6orf204 -0.54 -6.33 -0.32 7.71e-10 Diastolic blood pressure; LIHC cis rs870825 0.616 rs28459754 chr4:185636280 C/A cg04058563 chr4:185651563 MLF1IP 0.63 6.67 0.34 1.03e-10 Blood protein levels; LIHC cis rs1000083 0.915 rs2643573 chr5:96609704 C/T ch.5.96698337R chr5:96672581 NA 0.93 7.47 0.37 6.63e-13 Cisplatin-induced ototoxicity; LIHC cis rs8017423 0.967 rs7160032 chr14:90708472 A/G cg14092571 chr14:90743983 NA -0.37 -5.88 -0.3 9.9e-9 Mortality in heart failure; LIHC cis rs7116495 1.000 rs12293885 chr11:71816092 T/A cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs739401 0.611 rs391188 chr11:3047634 G/A cg05729581 chr11:3078854 CARS -0.42 -5.86 -0.3 1.08e-8 Longevity; LIHC cis rs317689 0.680 rs315140 chr12:69790780 A/T cg22834771 chr12:69754056 YEATS4 -0.39 -6.0 -0.31 4.9e-9 Response to diuretic therapy; LIHC cis rs7927771 0.864 rs4752838 chr11:47466006 G/A cg20135002 chr11:47629003 NA -0.57 -9.6 -0.46 1.8e-19 Subjective well-being; LIHC cis rs1707322 1.000 rs4660896 chr1:46372416 A/G cg06784218 chr1:46089804 CCDC17 0.34 6.09 0.31 3.11e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9309473 1.000 rs1403284 chr2:73726662 A/G cg20560298 chr2:73613845 ALMS1 0.52 5.94 0.31 7.02e-9 Metabolite levels; LIHC cis rs11233413 1.000 rs4944425 chr11:82776861 C/A cg24227371 chr11:82718527 RAB30 -0.36 -7.83 -0.39 6.19e-14 Economic and political preferences (feminism/equality); LIHC cis rs2607426 1.000 rs2607426 chr19:41274713 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.48 -6.12 -0.31 2.56e-9 Blood protein levels; LIHC cis rs11711311 0.712 rs3773683 chr3:113341007 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.66 -0.34 1.11e-10 IgG glycosylation; LIHC cis rs4820294 1.000 rs732856 chr22:38060691 C/G cg00292662 chr22:38071168 LGALS1 -0.64 -10.27 -0.49 9.46e-22 Fat distribution (HIV); LIHC trans rs11165623 0.740 rs12126692 chr1:96889258 C/G cg10631902 chr5:14652156 NA 0.32 8.12 0.4 8.61e-15 Hip circumference;Waist circumference; LIHC cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs2072499 0.750 rs10159384 chr1:156160822 C/T cg24450063 chr1:156163899 SLC25A44 0.76 8.22 0.41 4.36e-15 Testicular germ cell tumor; LIHC trans rs7615952 0.515 rs7637246 chr3:125678706 A/G cg07211511 chr3:129823064 LOC729375 -0.5 -6.35 -0.32 6.8e-10 Blood pressure (smoking interaction); LIHC cis rs644799 1.000 rs568668 chr11:95528209 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.14 0.68 5.42e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2404602 0.692 rs4641709 chr15:77047736 C/T cg03037974 chr15:76606532 NA -0.74 -14.6 -0.62 7.12e-38 Blood metabolite levels; LIHC cis rs4906332 1.000 rs17617307 chr14:103904965 C/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.16 -0.32 2e-9 Coronary artery disease; LIHC cis rs1801251 1.000 rs4517962 chr2:233578337 T/C cg25237894 chr2:233734115 C2orf82 0.56 10.94 0.51 4.4e-24 Coronary artery disease; LIHC cis rs4742903 0.967 rs10820601 chr9:106861281 G/A cg14250997 chr9:106856677 SMC2 0.42 7.42 0.37 9.36e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.54 8.49 0.42 6.32e-16 Schizophrenia; LIHC cis rs17428076 0.881 rs17581439 chr2:172737267 T/C cg13550731 chr2:172543902 DYNC1I2 0.38 6.14 0.32 2.24e-9 Myopia; LIHC trans rs73001065 0.792 rs16996148 chr19:19658472 G/T cg08270573 chr4:147443996 SLC10A7 -0.68 -6.09 -0.31 3.03e-9 LDL cholesterol; LIHC cis rs2933343 0.649 rs2638845 chr3:128587369 A/G cg24203234 chr3:128598194 ACAD9 0.44 6.13 0.31 2.42e-9 IgG glycosylation; LIHC cis rs3784262 1.000 rs12903551 chr15:58268372 C/T cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.33 -0.32 7.73e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs965469 0.779 rs1884563 chr20:3335540 T/C cg25506879 chr20:3388711 C20orf194 -0.52 -6.41 -0.33 4.8e-10 IFN-related cytopenia; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.01 0.58 9.97e-32 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13897145 chr3:113557582 GRAMD1C 0.41 6.2 0.32 1.61e-9 Cognitive function; LIHC cis rs12478296 1.000 rs56102931 chr2:243039936 A/G cg06360820 chr2:242988706 NA -0.84 -11.75 -0.54 5.1e-27 Obesity-related traits; LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs6545883 0.718 rs3771260 chr2:61762384 G/T cg15711740 chr2:61764176 XPO1 -0.44 -6.2 -0.32 1.62e-9 Tuberculosis; LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg10755058 chr3:40428713 ENTPD3 0.4 6.69 0.34 8.89e-11 Renal cell carcinoma; LIHC cis rs1865760 0.929 rs12195653 chr6:25958621 A/G cg03517284 chr6:25882590 NA -0.4 -6.05 -0.31 3.73e-9 Height; LIHC cis rs1775715 0.870 rs1755084 chr10:32253709 C/T cg14930904 chr10:32216787 ARHGAP12 0.38 6.8 0.35 4.57e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs4819052 0.851 rs4819044 chr21:46660118 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.52 0.53 3.51e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08772111 chr2:240002329 HDAC4 -0.38 -6.42 -0.33 4.55e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs2236918 0.710 rs2797602 chr1:242029206 G/T cg17736920 chr1:242011382 EXO1 0.41 6.04 0.31 3.99e-9 Menopause (age at onset); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg07962309 chr12:42628089 YAF2 -0.25 -6.21 -0.32 1.5e-9 Calcium levels; LIHC cis rs8005677 0.962 rs34917191 chr14:23387628 T/C cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs16858210 0.648 rs57604063 chr3:183578689 A/T cg25686905 chr3:183603175 PARL -0.48 -8.56 -0.42 3.82e-16 Menopause (age at onset); LIHC cis rs6570726 0.738 rs4495284 chr6:145916617 T/A cg13319975 chr6:146136371 FBXO30 -0.38 -6.02 -0.31 4.59e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs936229 0.749 rs6495127 chr15:75194490 C/T cg10253484 chr15:75165896 SCAMP2 -0.6 -7.02 -0.35 1.23e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs7959452 0.640 rs4274230 chr12:69700772 T/G cg22834771 chr12:69754056 YEATS4 -0.48 -8.26 -0.41 3.33e-15 Blood protein levels; LIHC cis rs317689 0.581 rs160829 chr12:69769538 G/C cg19645103 chr12:69753606 YEATS4 -0.52 -7.81 -0.39 6.88e-14 Response to diuretic therapy; LIHC cis rs250677 1.000 rs36069 chr5:148417253 G/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.95 -0.35 1.86e-11 Breast cancer; LIHC cis rs7572733 0.515 rs13408411 chr2:198825462 G/A cg00792783 chr2:198669748 PLCL1 0.46 6.81 0.35 4.41e-11 Dermatomyositis; LIHC cis rs7107174 1.000 rs10899460 chr11:78010080 A/G cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs7408868 0.908 rs1044006 chr19:15285052 T/C cg14696996 chr19:15285081 NOTCH3 0.56 7.34 0.37 1.61e-12 Pulse pressure; LIHC cis rs2034088 0.965 rs4968070 chr17:446162 A/G cg06217071 chr17:408420 NA 0.27 5.85 0.3 1.16e-8 Hip circumference adjusted for BMI; LIHC cis rs11148252 0.538 rs2296348 chr13:52710136 T/G cg00495681 chr13:53174319 NA 0.39 6.71 0.34 8.13e-11 Lewy body disease; LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC trans rs9914544 0.545 rs4393623 chr17:18775900 A/G cg21372672 chr17:16614065 CCDC144A -0.25 -6.06 -0.31 3.6e-9 Educational attainment (years of education); LIHC cis rs7772486 0.875 rs7766463 chr6:146364453 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.81 0.3 1.45e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg15664640 chr17:80829946 TBCD 0.39 6.14 0.32 2.3e-9 Glycated hemoglobin levels; LIHC cis rs853679 0.517 rs9393901 chr6:28136797 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs9814567 1.000 rs6801596 chr3:134252114 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 3.97e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7106204 0.668 rs7951530 chr11:24246904 T/C ch.11.24196551F chr11:24239977 NA 0.82 11.64 0.53 1.36e-26 Response to Homoharringtonine (cytotoxicity); LIHC trans rs2727020 0.595 rs10769583 chr11:49483193 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -22.08 -0.77 8.55e-68 Coronary artery disease; LIHC cis rs2204008 0.627 rs10878486 chr12:38148601 T/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.16e-23 Bladder cancer; LIHC cis rs2637266 1.000 rs2395394 chr10:78360679 G/C cg18941641 chr10:78392320 NA 0.28 5.85 0.3 1.17e-8 Pulmonary function; LIHC cis rs6061231 1.000 rs6061231 chr20:60956917 C/A cg03945807 chr20:60948434 NA 0.4 6.44 0.33 3.95e-10 Colorectal cancer; LIHC cis rs2952156 0.920 rs1476278 chr17:37836243 C/T cg00129232 chr17:37814104 STARD3 -0.56 -10.79 -0.5 1.5e-23 Asthma; LIHC cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC cis rs6502050 0.835 rs6502068 chr17:80112223 C/T cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs477692 1.000 rs580745 chr10:131414401 G/A cg05714579 chr10:131428358 MGMT 0.45 7.33 0.37 1.69e-12 Response to temozolomide; LIHC cis rs1712517 0.873 rs1163083 chr10:105038455 T/A cg05636881 chr10:105038444 INA 0.44 7.11 0.36 6.76e-12 Migraine; LIHC cis rs1008375 0.863 rs4698632 chr4:17614894 T/C cg16339924 chr4:17578868 LAP3 0.42 5.88 0.3 9.55e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs748404 0.631 rs12905772 chr15:43648444 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.56 9.99 0.48 9e-21 Lung cancer; LIHC cis rs533581 0.866 rs561795 chr16:88970818 A/G cg03970086 chr16:88974840 CBFA2T3 0.35 7.01 0.35 1.32e-11 Social autistic-like traits; LIHC cis rs10751667 0.643 rs10794343 chr11:925493 C/T cg06064525 chr11:970664 AP2A2 -0.54 -14.45 -0.62 2.82e-37 Alzheimer's disease (late onset); LIHC cis rs6835098 0.962 rs3733477 chr4:174090004 G/A cg08422745 chr4:174089978 GALNT7 -0.33 -5.88 -0.3 1e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs7756236 0.521 rs6907437 chr6:36625021 A/G cg08179530 chr6:36648295 CDKN1A 0.42 6.34 0.32 7.29e-10 QRS duration; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -6.97 -0.35 1.59e-11 Total body bone mineral density; LIHC cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.09e-10 Bipolar disorder; LIHC cis rs9951602 0.607 rs3017651 chr18:76668622 T/C cg00806245 chr18:76673096 NA -0.22 -5.81 -0.3 1.43e-8 Obesity-related traits; LIHC cis rs2404602 0.583 rs2139190 chr15:76555539 G/C cg22467129 chr15:76604101 ETFA -0.38 -6.32 -0.32 8.11e-10 Blood metabolite levels; LIHC cis rs3812831 0.661 rs2987458 chr13:114919835 A/G cg06611532 chr13:114900021 NA 0.42 7.69 0.38 1.5700000000000001e-13 Schizophrenia; LIHC cis rs12477438 0.520 rs4340581 chr2:99725025 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.33 0.64 9.22e-41 Chronic sinus infection; LIHC cis rs7618501 0.633 rs3774733 chr3:50037123 C/G cg21467203 chr3:49911342 NA -0.43 -7.78 -0.39 8.93e-14 Intelligence (multi-trait analysis); LIHC cis rs9303280 0.806 rs36095411 chr17:38031865 T/G cg17344932 chr17:38183730 MED24;SNORD124 0.38 5.85 0.3 1.13e-8 Self-reported allergy; LIHC cis rs2455799 0.594 rs11928773 chr3:15925135 A/G cg12698662 chr3:15914712 MIR563 -0.39 -7.36 -0.37 1.4e-12 Mean platelet volume; LIHC cis rs7909074 0.832 rs10793564 chr10:45386352 C/A cg05187965 chr10:45406764 TMEM72 -0.28 -7.15 -0.36 5.35e-12 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.4e-11 Diabetic kidney disease; LIHC cis rs7914558 1.000 rs2275271 chr10:104814162 T/C cg15744005 chr10:104629667 AS3MT -0.39 -8.86 -0.43 4.32e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs311392 0.526 rs311385 chr8:55101380 T/A cg20636351 chr8:55087400 NA -0.34 -7.09 -0.36 7.97e-12 Pelvic organ prolapse (moderate/severe); LIHC trans rs4927850 1.000 rs10881563 chr3:195750225 A/G cg16724585 chr3:197361211 NA -0.47 -6.6 -0.34 1.57e-10 Pancreatic cancer; LIHC cis rs6665290 0.836 rs12593 chr1:227172290 A/G cg10327440 chr1:227177885 CDC42BPA 1.12 21.68 0.76 3.39e-66 Myeloid white cell count; LIHC cis rs477692 0.685 rs534430 chr10:131398734 A/C cg19680672 chr10:131412579 MGMT -0.41 -6.37 -0.33 6e-10 Response to temozolomide; LIHC cis rs1577917 1.000 rs12663651 chr6:86701655 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.63 -0.46 1.43e-19 Response to antipsychotic treatment; LIHC cis rs6582630 0.519 rs12578283 chr12:38325349 A/T cg26384229 chr12:38710491 ALG10B 0.6 8.29 0.41 2.67e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg27572855 chr1:25598939 RHD 0.43 9.67 0.46 1.07e-19 Erythrocyte sedimentation rate; LIHC cis rs1707322 1.000 rs7527079 chr1:46413450 C/G cg06784218 chr1:46089804 CCDC17 0.36 6.44 0.33 3.94e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7572733 0.555 rs7420608 chr2:198915930 A/T cg03934865 chr2:198174659 NA 0.45 6.53 0.33 2.35e-10 Dermatomyositis; LIHC cis rs710865 0.541 rs12567768 chr1:19568603 T/A cg13387374 chr1:19411106 UBR4 0.42 6.53 0.33 2.31e-10 Brain structure; LIHC cis rs7618501 1.000 rs3749240 chr3:49750188 T/A cg24110177 chr3:50126178 RBM5 0.43 6.64 0.34 1.26e-10 Intelligence (multi-trait analysis); LIHC cis rs151997 0.962 rs28676922 chr5:50247221 C/T cg06027927 chr5:50259733 NA 0.6 7.87 0.39 4.86e-14 Callous-unemotional behaviour; LIHC cis rs4878497 0.542 rs10813815 chr9:32436683 G/C cg14296220 chr9:32431791 ACO1 0.6 10.11 0.48 3.38e-21 Inflammatory skin disease; LIHC cis rs6963495 0.818 rs73192143 chr7:105202415 A/G cg19920283 chr7:105172520 RINT1 0.66 5.98 0.31 5.58e-9 Bipolar disorder (body mass index interaction); LIHC cis rs1580019 0.587 rs6972365 chr7:32548931 T/A cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.12 0.31 2.56e-9 Cognitive ability; LIHC cis rs1570884 0.516 rs2146144 chr13:50170245 C/T cg03651054 chr13:50194643 NA 0.38 6.65 0.34 1.17e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs477895 0.713 rs882146 chr11:63976699 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 9.92 0.47 1.54e-20 Mean platelet volume; LIHC trans rs7395662 0.591 rs7482521 chr11:48609735 G/A cg15704280 chr7:45808275 SEPT13 -0.47 -7.01 -0.35 1.29e-11 HDL cholesterol; LIHC cis rs7582180 0.629 rs4851298 chr2:100949827 G/A cg14675211 chr2:100938903 LONRF2 0.53 8.42 0.41 1.05e-15 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.890 rs3750465 chr9:111900677 T/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.83 -0.35 3.95e-11 Menarche (age at onset); LIHC cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg12463550 chr7:65579703 CRCP 0.66 6.98 0.35 1.54e-11 Diabetic kidney disease; LIHC cis rs1552244 0.554 rs6768339 chr3:10006079 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 0.39 6.2 0.32 1.59e-9 Alzheimer's disease; LIHC cis rs798554 0.610 rs1182173 chr7:2878016 C/G cg19717773 chr7:2847554 GNA12 -0.41 -7.16 -0.36 4.87e-12 Height; LIHC cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg13393036 chr8:95962371 TP53INP1 -0.38 -8.61 -0.42 2.8e-16 Type 2 diabetes; LIHC cis rs57221529 0.766 rs4245972 chr5:578572 A/G cg09021430 chr5:549028 NA -0.45 -8.73 -0.43 1.14e-16 Lung disease severity in cystic fibrosis; LIHC cis rs34779708 0.966 rs4934537 chr10:35441512 C/T cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.46e-8 Menopause (age at onset); LIHC trans rs1728785 0.818 rs1645984 chr16:68628850 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.13 0.31 2.37e-9 Ulcerative colitis; LIHC cis rs365132 0.967 rs353471 chr5:176363429 T/C cg16309518 chr5:176445507 NA -0.58 -11.31 -0.52 2.13e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs2279817 0.908 rs12137775 chr1:18018927 G/T cg21791023 chr1:18019539 ARHGEF10L 0.63 7.96 0.4 2.57e-14 Neuroticism; LIHC trans rs6489882 0.703 rs10850096 chr12:113360786 T/C cg10175203 chr3:128143634 NA 0.4 6.43 0.33 4.19e-10 Chronic lymphocytic leukemia; LIHC cis rs3770081 1.000 rs73943920 chr2:86186195 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.75 -7.67 -0.38 1.8e-13 Facial emotion recognition (sad faces); LIHC cis rs9640161 0.830 rs11768108 chr7:150064150 C/T cg17279839 chr7:150038598 RARRES2 0.37 7.26 0.37 2.63e-12 Blood protein levels;Circulating chemerin levels; LIHC trans rs12478296 0.786 rs28802397 chr2:243049730 G/A cg01596870 chr19:55963115 NA -0.64 -8.52 -0.42 5.27e-16 Obesity-related traits; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11354472 chr22:17589511 IL17RA 0.42 6.43 0.33 4.39e-10 Immature fraction of reticulocytes; LIHC trans rs2243480 1.000 rs1404147 chr7:65264524 C/T cg10756647 chr7:56101905 PSPH 1.06 13.19 0.58 2.2e-32 Diabetic kidney disease; LIHC cis rs7772486 0.625 rs2050027 chr6:146116113 C/G cg23711669 chr6:146136114 FBXO30 -0.71 -12.91 -0.57 2.43e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs798554 0.610 rs1182209 chr7:2808595 C/T cg19717773 chr7:2847554 GNA12 -0.41 -7.32 -0.37 1.74e-12 Height; LIHC cis rs9814567 0.679 rs1880379 chr3:134330612 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7224685 0.539 rs2054039 chr17:4014538 C/A cg11204139 chr17:3907470 NA 0.67 11.3 0.52 2.3e-25 Type 2 diabetes; LIHC cis rs1494950 1.000 rs7442191 chr4:15023295 G/A cg12377275 chr4:15005593 CPEB2 0.84 7.35 0.37 1.46e-12 Political ideology; LIHC cis rs1005277 0.579 rs176880 chr10:38401417 C/G cg00409905 chr10:38381863 ZNF37A 0.6 10.6 0.5 6.66e-23 Extrinsic epigenetic age acceleration; LIHC cis rs9902453 1.000 rs11080114 chr17:28407287 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.59 -0.53 1.95e-26 Coffee consumption (cups per day); LIHC cis rs780096 0.967 rs1260333 chr2:27748624 A/G cg22903471 chr2:27725779 GCKR -0.31 -5.88 -0.3 9.91e-9 Total body bone mineral density; LIHC cis rs28595532 0.545 rs17516526 chr4:119259199 C/G cg21605333 chr4:119757512 SEC24D 0.79 6.65 0.34 1.19e-10 Cannabis dependence symptom count; LIHC cis rs1949733 0.701 rs4696828 chr4:8455604 G/A cg11789530 chr4:8429930 ACOX3 -0.76 -10.95 -0.51 3.99e-24 Response to antineoplastic agents; LIHC cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg13047869 chr3:10149882 C3orf24 0.54 6.49 0.33 2.99e-10 Alzheimer's disease; LIHC cis rs1451375 0.959 rs17133878 chr7:50620927 T/C cg14593290 chr7:50529359 DDC 0.35 5.76 0.3 1.88e-8 Malaria; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11339840 chr1:203596058 ATP2B4 0.43 6.4 0.33 5.12e-10 Pancreatic cancer; LIHC cis rs2425143 1.000 rs1118233 chr20:34228349 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.51 -5.86 -0.3 1.07e-8 Blood protein levels; LIHC cis rs933688 0.938 rs1477348 chr5:90707823 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.37 0.66 6.68e-45 Smoking behavior; LIHC cis rs6582630 0.502 rs11520278 chr12:38359642 T/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 2.97e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs2463822 1.000 rs2513052 chr11:62108248 C/G cg06239285 chr11:62104954 ASRGL1 0.93 7.04 0.36 1.06e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs13118159 0.801 rs7664474 chr4:1329116 T/A cg20887711 chr4:1340912 KIAA1530 0.46 6.64 0.34 1.22e-10 Longevity; LIHC cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs875971 1.000 rs937495 chr7:65779798 A/G cg18252515 chr7:66147081 NA 0.42 5.88 0.3 9.6e-9 Aortic root size; LIHC cis rs4900538 0.821 rs2009575 chr14:102820787 C/T cg18135206 chr14:102964638 TECPR2 -0.7 -10.75 -0.5 2.08e-23 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.41 0.33 4.8e-10 Total body bone mineral density; LIHC cis rs992157 0.835 rs11677953 chr2:219121663 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.76 -11.88 -0.54 1.68e-27 Colorectal cancer; LIHC cis rs7044106 0.791 rs747819 chr9:123488441 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.58 8.87 0.43 4.24e-17 Hip circumference adjusted for BMI; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg02782426 chr3:40428986 ENTPD3 0.33 6.12 0.31 2.64e-9 Renal cell carcinoma; LIHC cis rs10147008 1 rs10147008 chr14:59990474 G/A cg13540075 chr14:59894425 NA 0.42 6.97 0.35 1.6e-11 Tonsillectomy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24594383 chr20:62564955 DNAJC5 -0.45 -6.91 -0.35 2.43e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs17376456 0.877 rs9885329 chr5:93380278 G/A cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs56011263 0.687 rs4690187 chr4:703813 C/T cg14024328 chr4:719362 PCGF3 -0.47 -6.96 -0.35 1.78e-11 White blood cell count; LIHC cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs7613875 0.620 rs3774734 chr3:50108792 C/A cg05623727 chr3:50126028 RBM5 -0.34 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs2404602 0.735 rs11638767 chr15:76655938 T/C cg03037974 chr15:76606532 NA -0.65 -11.48 -0.53 4.96e-26 Blood metabolite levels; LIHC cis rs4819052 0.851 rs7276828 chr21:46695039 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.22 0.41 4.39e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10791323 0.569 rs5019134 chr11:133713082 G/C cg06766960 chr11:133703094 NA -0.65 -10.92 -0.51 5.15e-24 Childhood ear infection; LIHC cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg03517284 chr6:25882590 NA -0.5 -6.14 -0.32 2.24e-9 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg18357526 chr6:26021779 HIST1H4A 1.04 15.14 0.63 5.49e-40 Intelligence (multi-trait analysis); LIHC cis rs57590327 0.503 rs12638997 chr3:81844912 A/G cg07356753 chr3:81810745 GBE1 -0.54 -8.4 -0.41 1.24e-15 Extraversion; LIHC cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs11031096 0.782 rs4910888 chr11:4152915 G/A cg18678763 chr11:4115507 RRM1 -0.53 -8.16 -0.4 6.29e-15 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.77 0.62 1.56e-38 Prudent dietary pattern; LIHC trans rs3960554 0.932 rs60717745 chr7:75846083 C/G cg19862616 chr7:65841803 NCRNA00174 0.53 6.92 0.35 2.2e-11 Eotaxin levels; LIHC cis rs10489202 0.583 rs203782 chr1:167882386 A/G cg24449463 chr1:168025552 DCAF6 0.65 10.03 0.48 6.22e-21 Schizophrenia; LIHC cis rs7129220 0.588 rs61878634 chr11:10140114 A/T cg01453529 chr11:10209919 SBF2 -0.37 -6.69 -0.34 9.33e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs9534288 0.699 rs2897028 chr13:46656915 C/T cg15192986 chr13:46630673 CPB2 -0.44 -6.35 -0.32 6.91e-10 Blood protein levels; LIHC cis rs7086627 0.515 rs12245180 chr10:82211897 C/G cg00277334 chr10:82204260 NA -0.85 -14.22 -0.61 2.25e-36 Post bronchodilator FEV1; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02684603 chr4:89445054 PIGY 0.44 6.39 0.33 5.33e-10 Lung function (FEV1/FVC); LIHC trans rs7618501 0.699 rs2681781 chr3:49898273 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.6 9.42 0.45 6.81e-19 Intelligence (multi-trait analysis); LIHC cis rs62380364 0.566 rs1705565 chr5:88048457 C/T cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.903 rs11253504 chr10:956046 A/G cg26597838 chr10:835615 NA 1.18 12.71 0.57 1.35e-30 Eosinophil percentage of granulocytes; LIHC cis rs8044995 0.568 rs55675218 chr16:68323647 G/C cg09835421 chr16:68378352 PRMT7 -0.86 -9.0 -0.44 1.6e-17 Schizophrenia; LIHC cis rs4919694 0.901 rs12251035 chr10:104671459 A/C cg04362960 chr10:104952993 NT5C2 1.13 8.8 0.43 6.86e-17 Arsenic metabolism; LIHC cis rs2921073 0.605 rs2976933 chr8:8254875 A/G cg14343924 chr8:8086146 FLJ10661 0.49 5.99 0.31 5.31e-9 Parkinson's disease; LIHC cis rs864643 1.000 rs1513214 chr3:39560265 T/A cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs1878931 0.545 rs28603 chr16:3449479 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -7.73 -0.39 1.23e-13 Body mass index (adult); LIHC cis rs9457247 1.000 rs439553 chr6:167391212 A/G cg23791538 chr6:167370224 RNASET2 -0.66 -11.39 -0.52 1.08e-25 Crohn's disease; LIHC cis rs875971 0.862 rs2024192 chr7:66041447 G/T cg18252515 chr7:66147081 NA 0.45 6.57 0.33 1.83e-10 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23018242 chr22:31608245 LIMK2 0.54 7.01 0.35 1.25e-11 Lung function (FEV1/FVC); LIHC cis rs1670533 0.872 rs11727136 chr4:1051804 G/A cg27284194 chr4:1044797 NA 0.6 8.96 0.44 2.09e-17 Recombination rate (females); LIHC cis rs11608355 0.515 rs11609630 chr12:109918934 C/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs6750047 0.719 rs4670232 chr2:38272033 C/G cg07380506 chr2:38303506 CYP1B1 0.5 5.94 0.31 7.01e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs4730250 0.708 rs74983157 chr7:106823951 A/G cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Osteoarthritis; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg20607798 chr8:58055168 NA 0.64 8.21 0.41 4.61e-15 Developmental language disorder (linguistic errors); LIHC cis rs12744310 1.000 rs55892603 chr1:41773994 T/C cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7091068 0.616 rs10748611 chr10:95482761 A/C cg20715218 chr10:95462985 C10orf4 0.54 5.82 0.3 1.32e-8 Urinary tract infection frequency; LIHC cis rs10493773 1.000 rs2274738 chr1:86119898 A/G cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.23 -0.36 3.12e-12 Urate levels in overweight individuals; LIHC cis rs7208859 0.623 rs11650271 chr17:29213943 C/T cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg26818010 chr10:134567672 INPP5A -0.78 -9.66 -0.46 1.15e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8017423 0.967 rs55894943 chr14:90714799 A/G cg14092571 chr14:90743983 NA -0.38 -6.04 -0.31 4.01e-9 Mortality in heart failure; LIHC cis rs62179067 0.786 rs11891599 chr2:179940326 G/A cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs62458065 0.513 rs10268803 chr7:32547835 A/G cg06627557 chr7:32535165 LSM5;AVL9 -0.72 -7.02 -0.35 1.22e-11 Metabolite levels (HVA/MHPG ratio); LIHC cis rs2204008 0.837 rs11180821 chr12:38242843 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.9 0.3 8.58e-9 Bladder cancer; LIHC cis rs6964587 1.000 rs9969198 chr7:91567492 G/T cg17063962 chr7:91808500 NA -1.01 -19.28 -0.72 1.37e-56 Breast cancer; LIHC cis rs796364 0.806 rs79156935 chr2:200913822 T/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs10791323 0.601 rs7946883 chr11:133733864 T/C cg15485101 chr11:133734466 NA 0.27 6.35 0.32 6.84e-10 Childhood ear infection; LIHC cis rs9457247 0.508 rs9459874 chr6:167504127 A/G cg07741184 chr6:167504864 NA -0.28 -7.19 -0.36 3.98e-12 Crohn's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12232852 chr3:69129018 UBA3 0.49 6.85 0.35 3.36e-11 Pancreatic cancer; LIHC cis rs4888262 0.545 rs58136167 chr16:74700628 G/A cg01733217 chr16:74700730 RFWD3 0.86 18.02 0.7 1.7e-51 Testicular germ cell tumor; LIHC cis rs7395581 0.877 rs10838690 chr11:47335075 A/G cg25783544 chr11:47291846 MADD 0.41 5.95 0.31 6.8e-9 HDL cholesterol; LIHC cis rs5753618 0.561 rs737887 chr22:31696615 A/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.8 -0.39 7.68e-14 Colorectal cancer; LIHC cis rs17253792 0.822 rs80174205 chr14:56058694 T/C cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.15e-10 Putamen volume; LIHC cis rs4474465 0.850 rs7938257 chr11:78224908 A/G cg02023728 chr11:77925099 USP35 -0.38 -6.58 -0.34 1.74e-10 Alzheimer's disease (survival time); LIHC cis rs10540 1.000 rs35874808 chr11:506442 G/T cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.71e-15 Body mass index; LIHC trans rs801193 0.901 rs4273746 chr7:66301111 C/T cg18876405 chr7:65276391 NA -0.47 -7.53 -0.38 4.47e-13 Aortic root size; LIHC cis rs67311347 1.000 rs9834052 chr3:40399060 G/A cg09455208 chr3:40491958 NA 0.33 6.55 0.33 2.06e-10 Renal cell carcinoma; LIHC trans rs7618501 0.735 rs9876508 chr3:49780844 G/A cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC cis rs4638749 0.677 rs7568919 chr2:108832376 C/A cg25838818 chr2:108905173 SULT1C2 -0.4 -6.97 -0.35 1.68e-11 Blood pressure; LIHC cis rs6450176 0.909 rs67721004 chr5:53290571 T/C ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.29 -0.64 1.35e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs4942242 0.574 rs9533557 chr13:44197487 C/G cg19169023 chr15:41853346 TYRO3 0.51 6.94 0.35 1.96e-11 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs3741404 0.594 rs11231704 chr11:63898182 C/T cg05555928 chr11:63887634 MACROD1 0.46 6.63 0.34 1.32e-10 Platelet count; LIHC cis rs11098499 0.754 rs7672594 chr4:120248543 A/C cg09307838 chr4:120376055 NA 0.71 11.26 0.52 3.14e-25 Corneal astigmatism; LIHC cis rs722599 0.748 rs1059326 chr14:75369385 C/T cg11812906 chr14:75593930 NEK9 -0.43 -6.99 -0.35 1.47e-11 IgG glycosylation; LIHC cis rs2180341 0.883 rs6904630 chr6:127696869 A/G cg27446573 chr6:127587934 RNF146 1.03 16.24 0.66 2.33e-44 Breast cancer; LIHC cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg05527609 chr1:210001259 C1orf107 0.45 6.54 0.33 2.21e-10 Cleft lip with or without cleft palate; LIHC cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.67 0.42 1.73e-16 Platelet count; LIHC cis rs10193935 0.786 rs10178087 chr2:42409631 C/A cg27598129 chr2:42591480 NA -0.76 -11.28 -0.52 2.63e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs9303401 0.646 rs9303403 chr17:57219300 C/T cg12560992 chr17:57184187 TRIM37 -0.52 -7.37 -0.37 1.33e-12 Cognitive test performance; LIHC cis rs7149337 0.805 rs71422017 chr14:51612417 A/T cg23942311 chr14:51606299 NA 0.35 7.33 0.37 1.7e-12 Cancer; LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg14709524 chr16:89940631 TCF25 0.59 7.54 0.38 4.25e-13 Skin colour saturation; LIHC cis rs11122272 0.735 rs2739507 chr1:231527329 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.43 -0.49 2.61e-22 Hemoglobin concentration; LIHC cis rs10504229 1.000 rs68114352 chr8:58196081 C/T cg20607798 chr8:58055168 NA 0.59 6.85 0.35 3.44e-11 Developmental language disorder (linguistic errors); LIHC trans rs2000813 0.789 rs12970066 chr18:47107152 C/G cg01564661 chr14:105942636 CRIP2 0.34 6.08 0.31 3.29e-9 Coronary artery disease; LIHC cis rs4450131 0.522 rs11245325 chr10:126348061 C/T cg20435097 chr10:126320824 FAM53B 0.67 12.2 0.55 1.12e-28 White blood cell count (basophil); LIHC trans rs877282 0.583 rs11253441 chr10:828288 C/T cg22713356 chr15:30763199 NA -0.85 -7.28 -0.37 2.24e-12 Uric acid levels; LIHC cis rs2153535 0.580 rs969421 chr6:8451949 A/C cg07606381 chr6:8435919 SLC35B3 0.8 11.98 0.54 7.16e-28 Motion sickness; LIHC cis rs7089973 0.604 rs17663670 chr10:116596269 A/C cg23260525 chr10:116636907 FAM160B1 -0.35 -6.87 -0.35 3.11e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs10744422 0.800 rs1696320 chr12:123269814 A/G cg22842854 chr12:123319900 HIP1R -0.64 -8.09 -0.4 1.07e-14 Schizophrenia; LIHC cis rs67311347 0.713 rs73073505 chr3:40310693 C/T cg13409248 chr3:40428643 ENTPD3 0.41 6.5 0.33 2.91e-10 Renal cell carcinoma; LIHC cis rs9814567 1.000 rs2177601 chr3:134245434 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4631830 0.683 rs11004409 chr10:51498019 G/C cg16070123 chr10:51489643 NA 0.37 5.9 0.3 8.68e-9 Prostate-specific antigen levels; LIHC cis rs3862030 0.839 rs7078679 chr10:104284017 C/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.5 -7.57 -0.38 3.52e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 11.86 0.54 2.09e-27 Platelet count; LIHC cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg02290350 chr8:58132656 NA 0.4 8.44 0.42 9.38e-16 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC trans rs35110281 0.666 rs2236665 chr21:45108987 C/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.47 6.3 0.32 9.04e-10 Mean corpuscular volume; LIHC cis rs9303401 0.614 rs35245220 chr17:56510305 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.95 12.65 0.56 2.31e-30 Cognitive test performance; LIHC cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg11301795 chr4:187892539 NA -0.27 -7.13 -0.36 5.85e-12 Lobe attachment (rater-scored or self-reported); LIHC trans rs66573146 0.831 rs66645969 chr4:6985614 G/A cg07817883 chr1:32538562 TMEM39B 1.07 9.34 0.45 1.3e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs6964587 1.000 rs7797369 chr7:91570615 C/A cg17063962 chr7:91808500 NA -1.01 -19.21 -0.72 2.67e-56 Breast cancer; LIHC cis rs892961 0.899 rs312911 chr17:75414585 A/C cg01320579 chr17:75405842 SEPT9 0.52 8.91 0.43 3.04e-17 Airflow obstruction; LIHC cis rs7633770 0.735 rs4683271 chr3:46684823 A/G cg11219411 chr3:46661640 NA -0.42 -7.12 -0.36 6.49e-12 Coronary artery disease; LIHC cis rs11122272 0.735 rs2749723 chr1:231493302 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -11.3 -0.52 2.27e-25 Hemoglobin concentration; LIHC cis rs1707322 0.717 rs11211161 chr1:46148138 A/C cg03146154 chr1:46216737 IPP 0.58 9.75 0.47 5.74e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.84 0.54 2.41e-27 Prudent dietary pattern; LIHC cis rs6060987 1 rs6060987 chr20:30427077 T/A cg13852791 chr20:30311386 BCL2L1 0.84 8.87 0.43 4e-17 Mean corpuscular volume; LIHC cis rs10916814 0.610 rs10799641 chr1:20897250 G/A cg24502330 chr1:20914028 CDA -0.31 -6.76 -0.34 6.01e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7027203 0.828 rs10821229 chr9:96595136 A/C cg13679303 chr9:96623674 NA -0.3 -6.72 -0.34 7.82e-11 DNA methylation (variation); LIHC cis rs4901869 0.897 rs12878587 chr14:59339378 C/G cg02291164 chr14:59296302 NA 0.47 6.07 0.31 3.48e-9 Panic disorder; LIHC cis rs7613875 0.537 rs6446195 chr3:50070853 A/G cg24110177 chr3:50126178 RBM5 0.54 8.79 0.43 7.3e-17 Body mass index; LIHC cis rs10256972 0.933 rs35696159 chr7:1047194 A/G cg04025307 chr7:1156635 C7orf50 0.49 8.05 0.4 1.38e-14 Longevity;Endometriosis; LIHC cis rs12142240 0.698 rs6703374 chr1:46862332 C/G cg14993813 chr1:46806288 NSUN4 -0.66 -5.97 -0.31 5.89e-9 Menopause (age at onset); LIHC cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg18404041 chr3:52824283 ITIH1 -0.6 -9.61 -0.46 1.65e-19 Bipolar disorder; LIHC cis rs11227306 0.934 rs7102454 chr11:65594820 C/T cg00576331 chr11:65640516 EFEMP2 0.42 6.09 0.31 3.05e-9 DNA methylation (variation); LIHC cis rs12893668 0.703 rs35498576 chr14:104025893 T/C cg19000871 chr14:103996768 TRMT61A -0.42 -6.97 -0.35 1.65e-11 Reticulocyte count; LIHC cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs1814175 0.791 rs11040472 chr11:49703116 C/T cg18944383 chr4:111397179 ENPEP 0.25 6.32 0.32 7.95e-10 Height; LIHC cis rs826838 0.935 rs3886109 chr12:39189243 C/T cg26384229 chr12:38710491 ALG10B 0.85 11.0 0.51 2.59e-24 Heart rate; LIHC cis rs6429082 0.509 rs12027995 chr1:235517607 C/G cg26050004 chr1:235667680 B3GALNT2 0.4 5.79 0.3 1.58e-8 Adiposity; LIHC cis rs67311347 0.866 rs56331709 chr3:40356558 A/C cg00656387 chr3:40428638 ENTPD3 0.38 5.9 0.3 8.91e-9 Renal cell carcinoma; LIHC cis rs13108904 0.936 rs4974540 chr4:1213463 C/T cg02980000 chr4:1222292 CTBP1 -0.54 -7.51 -0.38 5.16e-13 Obesity-related traits; LIHC cis rs5758511 0.680 rs5758651 chr22:42609148 T/C cg00645731 chr22:42541494 CYP2D7P1 0.53 8.56 0.42 3.8e-16 Birth weight; LIHC trans rs1814175 0.616 rs28417656 chr11:50040152 C/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs919433 0.617 rs10931791 chr2:198573612 A/C cg00792783 chr2:198669748 PLCL1 -0.41 -5.83 -0.3 1.31e-8 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs2727020 0.553 rs4980447 chr11:49591662 T/C cg18944383 chr4:111397179 ENPEP 0.35 8.19 0.4 5.35e-15 Coronary artery disease; LIHC cis rs6429082 0.905 rs12405889 chr1:235597252 A/C cg26050004 chr1:235667680 B3GALNT2 -0.4 -6.28 -0.32 1.03e-9 Adiposity; LIHC cis rs11673344 0.704 rs1726719 chr19:37418032 T/C cg27390819 chr19:37464633 NA -0.48 -5.82 -0.3 1.35e-8 Obesity-related traits; LIHC cis rs2380220 0.574 rs9374322 chr6:95998994 G/A cg23517279 chr6:96025343 MANEA 0.54 5.98 0.31 5.71e-9 Behavioural disinhibition (generation interaction); LIHC cis rs875971 0.929 rs6970860 chr7:65976634 A/G cg11764359 chr7:65958608 NA 0.91 16.91 0.67 4.67e-47 Aortic root size; LIHC cis rs924607 1.000 rs11746907 chr5:598224 G/A cg04221910 chr5:616842 CEP72 -0.4 -7.04 -0.36 1.08e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs4790333 1.000 rs4790333 chr17:2262703 A/G cg02569219 chr17:2266849 SGSM2 -0.63 -10.25 -0.48 1.16e-21 Proinsulin levels; LIHC cis rs7587476 0.601 rs13021937 chr2:215673937 C/T cg04530015 chr2:215796436 ABCA12 0.45 7.55 0.38 4.06e-13 Neuroblastoma; LIHC cis rs9517320 0.515 rs4771307 chr13:99221879 A/G cg20487152 chr13:99095054 FARP1 -0.38 -6.09 -0.31 2.98e-9 Longevity; LIHC cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.08 0.31 3.29e-9 Menopause (age at onset); LIHC cis rs6500602 0.702 rs3761680 chr16:4524060 C/A cg08645402 chr16:4508243 NA 0.46 9.05 0.44 1.14e-17 Schizophrenia; LIHC cis rs10256972 0.640 rs10271082 chr7:1081562 G/C cg07308232 chr7:1071921 C7orf50 -0.41 -6.49 -0.33 2.97e-10 Longevity;Endometriosis; LIHC cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg02931644 chr1:25747376 RHCE -0.34 -7.16 -0.36 4.97e-12 Plateletcrit;Mean corpuscular volume; LIHC cis rs8062405 0.656 rs7189927 chr16:28913787 T/C cg07451762 chr16:28383216 NA -0.33 -6.03 -0.31 4.22e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs7618501 0.633 rs11925192 chr3:50038664 G/A cg21659725 chr3:3221576 CRBN 0.67 10.96 0.51 3.8e-24 Intelligence (multi-trait analysis); LIHC cis rs5769765 0.955 rs2319465 chr22:50265784 A/C cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs7666738 0.546 rs7679681 chr4:98882221 A/G cg05340658 chr4:99064831 C4orf37 0.52 6.85 0.35 3.43e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs2839186 0.814 rs12482209 chr21:47664275 C/G cg12016809 chr21:47604291 C21orf56 -0.45 -6.77 -0.34 5.71e-11 Testicular germ cell tumor; LIHC cis rs2777491 0.789 rs316617 chr15:41795900 C/T cg18705301 chr15:41695430 NDUFAF1 0.47 6.78 0.34 5.13e-11 Ulcerative colitis; LIHC cis rs7095944 0.584 rs4962693 chr10:126424835 C/T cg08799069 chr10:126477246 METTL10 -0.34 -5.98 -0.31 5.75e-9 Asthma; LIHC cis rs9733 0.596 rs11204704 chr1:150671630 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.06e-9 Tonsillectomy; LIHC cis rs6831352 0.879 rs29001215 chr4:100051722 T/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg11494091 chr17:61959527 GH2 0.46 8.17 0.4 6.12e-15 Prudent dietary pattern; LIHC cis rs9611565 0.572 rs139569 chr22:42211141 A/G cg06634786 chr22:41940651 POLR3H -0.59 -6.61 -0.34 1.48e-10 Vitiligo; LIHC cis rs6089584 0.566 rs6061972 chr20:60610245 C/T cg06108461 chr20:60628389 TAF4 -0.65 -9.19 -0.44 4.01e-18 Body mass index; LIHC cis rs6088590 1.000 rs6119512 chr20:33306904 T/C cg06115741 chr20:33292138 TP53INP2 0.61 8.78 0.43 8.17e-17 Coronary artery disease; LIHC trans rs11039798 1.000 rs7131020 chr11:48642132 A/G cg15704280 chr7:45808275 SEPT13 0.59 6.05 0.31 3.74e-9 Axial length; LIHC cis rs6442522 0.898 rs2219251 chr3:15429168 G/A cg16303742 chr3:15540471 COLQ 0.41 6.94 0.35 1.92e-11 Uric acid levels; LIHC cis rs8016982 0.662 rs8014406 chr14:81657760 A/C cg01989461 chr14:81687754 GTF2A1 0.54 9.58 0.46 2.14e-19 Schizophrenia; LIHC cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg04944784 chr2:26401820 FAM59B -0.71 -9.07 -0.44 9.29e-18 Gut microbiome composition (summer); LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg26939375 chr7:64535504 NA 0.47 8.29 0.41 2.59e-15 Calcium levels; LIHC cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs595982 0.661 rs657008 chr19:49373632 A/G cg21252483 chr19:49399788 TULP2 -0.46 -7.57 -0.38 3.59e-13 Red cell distribution width; LIHC cis rs12477438 0.520 rs7605843 chr2:99811894 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.19 21.06 0.75 1.02e-63 Chronic sinus infection; LIHC cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs9834052 chr3:40399060 G/A cg24209194 chr3:40518798 ZNF619 0.42 5.97 0.31 6.06e-9 Renal cell carcinoma; LIHC cis rs17401966 1.000 rs2275424 chr1:10356562 C/A cg15208524 chr1:10270712 KIF1B 0.46 6.65 0.34 1.15e-10 Hepatocellular carcinoma; LIHC cis rs7224737 1.000 rs35184688 chr17:40272406 G/C cg20291162 chr17:40259547 DHX58 -0.39 -5.94 -0.31 6.99e-9 Fibrinogen levels; LIHC cis rs7707921 0.881 rs73136777 chr5:81434479 T/A cg15871215 chr5:81402204 ATG10 -0.61 -5.9 -0.3 8.67e-9 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15421363 chr5:131826865 IRF1 0.41 6.49 0.33 2.94e-10 Lung function (FEV1/FVC); LIHC cis rs7903847 0.642 rs6584128 chr10:99171926 G/T cg06359132 chr10:99160096 RRP12 0.38 5.96 0.31 6.36e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs7824557 0.614 rs2736277 chr8:11218893 C/T cg21775007 chr8:11205619 TDH -0.45 -7.12 -0.36 6.53e-12 Retinal vascular caliber; LIHC cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg05368731 chr17:41323189 NBR1 0.73 12.56 0.56 5.19e-30 Menopause (age at onset); LIHC cis rs7772486 0.659 rs9376957 chr6:146011064 C/T cg23711669 chr6:146136114 FBXO30 -0.63 -11.47 -0.53 5.66e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs992157 1.000 rs3731859 chr2:219124222 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.88 0.57 3.23e-31 Colorectal cancer; LIHC cis rs2932538 0.922 rs6698030 chr1:113138318 G/A cg22162597 chr1:113214053 CAPZA1 0.71 9.59 0.46 1.87e-19 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs4820539 0.902 rs737846 chr22:23460669 A/G cg21100191 chr22:23484243 RTDR1 0.9 16.17 0.66 4.42e-44 Bone mineral density; LIHC cis rs4819052 0.679 rs8132135 chr21:46694782 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.66 0.38 1.9e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11122272 0.766 rs1435166 chr1:231502310 T/C cg06096015 chr1:231504339 EGLN1 0.52 9.58 0.46 2.1e-19 Hemoglobin concentration; LIHC cis rs1577917 0.771 rs9450290 chr6:86233397 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 11.99 0.54 6.85e-28 Response to antipsychotic treatment; LIHC cis rs7707921 1.000 rs2407064 chr5:81457358 C/A cg15871215 chr5:81402204 ATG10 0.6 5.89 0.3 9.03e-9 Breast cancer; LIHC cis rs80282103 0.867 rs12241632 chr10:1069070 A/T cg08668510 chr10:1095578 IDI1 0.69 7.52 0.38 4.91e-13 Glomerular filtration rate (creatinine); LIHC cis rs943466 0.614 rs4711345 chr6:33730954 G/A cg25922239 chr6:33757077 LEMD2 -0.45 -7.24 -0.36 3.07e-12 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.12.1981639F chr12:100732545 SCYL2 -0.28 -6.05 -0.31 3.87e-9 Cognitive function; LIHC cis rs9640161 0.742 rs2108852 chr7:150019628 T/C cg10018233 chr7:150070692 REPIN1 0.56 9.53 0.46 2.96e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs9611565 0.729 rs203320 chr22:41913477 T/C cg03806693 chr22:41940476 POLR3H -0.52 -6.86 -0.35 3.29e-11 Vitiligo; LIHC cis rs589448 0.902 rs315124 chr12:69771727 G/A cg20891283 chr12:69753455 YEATS4 0.94 22.36 0.77 6.84e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs67460515 0.892 rs13073147 chr3:161045237 T/C cg03342759 chr3:160939853 NMD3 -0.62 -9.26 -0.45 2.31e-18 Parkinson's disease; LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg00280220 chr17:61926910 NA -0.42 -6.71 -0.34 8.13e-11 Prudent dietary pattern; LIHC cis rs8083850 0.731 rs56291455 chr18:50830973 C/A cg24270629 chr18:50823537 DCC -0.55 -8.62 -0.42 2.6e-16 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26804004 chr15:77155428 SCAPER 0.27 6.22 0.32 1.48e-9 Cognitive function; LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs477692 0.905 rs509041 chr10:131424948 A/G cg05714579 chr10:131428358 MGMT 0.5 8.55 0.42 4.06e-16 Response to temozolomide; LIHC cis rs651907 0.535 rs58658478 chr3:101511667 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.66 10.67 0.5 3.84e-23 Colorectal cancer; LIHC cis rs10242455 0.557 rs57830676 chr7:99281363 C/T cg18809830 chr7:99032528 PTCD1 -0.83 -6.62 -0.34 1.42e-10 Blood metabolite levels; LIHC cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg17554472 chr22:41940697 POLR3H 0.56 5.99 0.31 5.18e-9 Vitiligo; LIHC cis rs12887734 0.546 rs66676135 chr14:104271504 G/A cg24130564 chr14:104152367 KLC1 -0.44 -7.13 -0.36 6.01e-12 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.71 0.38 1.35e-13 Prudent dietary pattern; LIHC trans rs56011263 0.687 rs4690188 chr4:703930 G/C cg12575136 chr18:32820987 ZNF397 0.47 7.01 0.35 1.28e-11 White blood cell count; LIHC cis rs12413816 0.818 rs35567671 chr10:13769722 C/A cg16485048 chr10:13749193 FRMD4A 0.49 6.72 0.34 7.67e-11 Red cell distribution width; LIHC cis rs12711979 0.765 rs881852 chr2:3821508 A/G cg17052675 chr2:3827356 NA -0.41 -6.92 -0.35 2.23e-11 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs600806 0.778 rs2787015 chr1:110009434 A/C cg02415029 chr1:110025642 ATXN7L2 -0.48 -5.98 -0.31 5.73e-9 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.512 rs45500192 chr22:42177899 A/G cg06634786 chr22:41940651 POLR3H -0.73 -7.54 -0.38 4.21e-13 Vitiligo; LIHC cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg03806693 chr22:41940476 POLR3H -1.07 -11.37 -0.52 1.22e-25 Crohn's disease;Inflammatory bowel disease; LIHC cis rs17376456 0.569 rs2924374 chr5:93151141 T/C cg25358565 chr5:93447407 FAM172A -0.79 -7.68 -0.38 1.74e-13 Diabetic retinopathy; LIHC cis rs9291683 0.588 rs13133766 chr4:10019732 C/T cg11266682 chr4:10021025 SLC2A9 0.33 7.15 0.36 5.29e-12 Bone mineral density; LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.71 -0.3 2.45e-8 Total body bone mineral density; LIHC cis rs72627123 0.656 rs17096949 chr14:74602360 A/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.84 7.81 0.39 7.1e-14 Morning vs. evening chronotype; LIHC trans rs561341 1.000 rs4795670 chr17:30244839 T/C cg20587970 chr11:113659929 NA -0.69 -7.87 -0.39 4.66e-14 Hip circumference adjusted for BMI; LIHC cis rs4689592 0.503 rs11937667 chr4:7057037 C/G cg06697600 chr4:7070879 GRPEL1 0.63 9.58 0.46 2.04e-19 Monocyte percentage of white cells; LIHC cis rs919433 0.963 rs2043016 chr2:198146381 C/T cg03934865 chr2:198174659 NA -0.62 -10.02 -0.48 7.06e-21 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1843834 0.898 rs12623277 chr2:225548072 T/G cg22509189 chr2:225307070 NA -0.52 -6.97 -0.35 1.64e-11 IgE levels in asthmatics (D.p. specific); LIHC cis rs9733 0.650 rs12125672 chr1:150554470 A/T cg13175981 chr1:150552382 MCL1 0.62 9.73 0.47 6.5e-20 Tonsillectomy; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg13239297 chr3:50192725 SEMA3F -0.41 -6.68 -0.34 9.92e-11 Calcium levels; LIHC cis rs9291683 0.632 rs12508991 chr4:10041104 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.63e-13 Bone mineral density; LIHC cis rs796364 0.806 rs10931889 chr2:201101900 G/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.64 -7.02 -0.36 1.17e-11 Schizophrenia; LIHC cis rs9916302 0.610 rs11078902 chr17:37631883 C/G cg03013999 chr17:37608204 MED1 0.36 5.91 0.3 8.43e-9 Glomerular filtration rate (creatinine); LIHC cis rs2576037 0.526 rs2010834 chr18:44560875 C/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.47 6.76 0.34 5.88e-11 Personality dimensions; LIHC cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.09e-8 Bipolar disorder; LIHC cis rs10744422 1.000 rs7309225 chr12:123288439 A/G cg22842854 chr12:123319900 HIP1R -0.63 -7.66 -0.38 1.87e-13 Schizophrenia; LIHC cis rs12701220 0.522 rs12334290 chr7:1054517 A/G cg09177884 chr7:1199841 ZFAND2A -0.45 -5.73 -0.3 2.26e-8 Bronchopulmonary dysplasia; LIHC cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg21226059 chr5:178986404 RUFY1 0.38 5.78 0.3 1.71e-8 Lung cancer; LIHC cis rs1448094 0.520 rs12304244 chr12:86272823 C/T cg02569458 chr12:86230093 RASSF9 0.44 5.99 0.31 5.45e-9 Major depressive disorder; LIHC cis rs10883723 0.773 rs11191303 chr10:104255158 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1348850 0.747 rs1047884 chr2:178488281 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.63 8.48 0.42 6.99e-16 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs79387448 0.745 rs72995626 chr2:103162580 T/C cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg06634786 chr22:41940651 POLR3H 0.82 9.06 0.44 1.02e-17 Vitiligo; LIHC cis rs921968 0.643 rs524902 chr2:219433357 A/C cg02985541 chr2:219472218 PLCD4 0.44 8.35 0.41 1.7e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs6120849 0.663 rs13041792 chr20:33545055 G/A cg07148914 chr20:33460835 GGT7 0.53 5.93 0.31 7.54e-9 Protein C levels; LIHC cis rs798554 1.000 rs798559 chr7:2758341 T/C cg19346786 chr7:2764209 NA -0.41 -6.01 -0.31 4.82e-9 Height; LIHC cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg18867708 chr6:26865862 GUSBL1 -0.56 -8.6 -0.42 2.82e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs9309711 0.621 rs7586472 chr2:3473670 G/A cg04359351 chr2:3481828 TTC15 0.29 5.97 0.31 5.94e-9 Neurofibrillary tangles; LIHC cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg13047869 chr3:10149882 C3orf24 0.51 5.89 0.3 9e-9 Alzheimer's disease; LIHC cis rs1552244 0.572 rs17032426 chr3:10167112 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.59 -0.56 4.11e-30 Alzheimer's disease; LIHC cis rs12594515 1.000 rs8025258 chr15:45987554 C/A cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.69e-19 Waist circumference;Weight; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26376749 chr17:30677620 ZNF207 0.41 6.16 0.32 2.08e-9 Cognitive function; LIHC cis rs7249142 0.549 rs3787040 chr19:19297292 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.38 -6.43 -0.33 4.37e-10 IgG glycosylation; LIHC cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg03452623 chr4:187889614 NA -0.32 -8.36 -0.41 1.55e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs9916302 0.904 rs8066704 chr17:37477218 C/T cg00129232 chr17:37814104 STARD3 0.38 6.09 0.31 2.98e-9 Glomerular filtration rate (creatinine); LIHC cis rs1997103 1.000 rs10278894 chr7:55404748 A/G cg17469321 chr7:55412551 NA 0.48 7.01 0.35 1.32e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs17376456 0.825 rs17314762 chr5:93231200 C/T cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs10788264 0.504 rs4751885 chr10:124020305 G/T cg04162153 chr10:124029871 BTBD16 0.42 5.82 0.3 1.33e-8 Total body bone mineral density; LIHC cis rs7208859 0.673 rs999796 chr17:29159404 G/C cg14067834 chr17:29058358 SUZ12P 0.64 6.57 0.33 1.83e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9811920 0.609 rs793460 chr3:99615733 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg07424592 chr7:64974309 NA 0.82 9.23 0.45 2.79e-18 Diabetic kidney disease; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC cis rs735396 1.000 rs735396 chr12:121438844 T/C cg25281562 chr12:121454272 C12orf43 0.33 5.78 0.3 1.67e-8 N-glycan levels; LIHC cis rs1552244 0.882 rs68080705 chr3:10025743 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.93 0.47 1.33e-20 Alzheimer's disease; LIHC cis rs2625529 0.775 rs4777489 chr15:72430434 C/T cg16672083 chr15:72433130 SENP8 0.32 6.09 0.31 3.07e-9 Red blood cell count; LIHC cis rs1443512 0.812 rs2078098 chr12:54337527 C/A cg12374095 chr12:54320830 NA 0.4 5.81 0.3 1.42e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs2274273 0.967 rs1009978 chr14:55603061 C/G cg01864836 chr14:55583639 NA -0.41 -7.96 -0.4 2.5e-14 Protein biomarker; LIHC cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg04267008 chr7:1944627 MAD1L1 -0.58 -9.03 -0.44 1.27e-17 Bipolar disorder and schizophrenia; LIHC trans rs1814175 0.616 rs10839341 chr11:49742615 G/A cg15704280 chr7:45808275 SEPT13 -0.97 -20.37 -0.74 5.91e-61 Height; LIHC cis rs2334880 0.836 rs9934715 chr16:71757387 C/G cg06353428 chr16:71660113 MARVELD3 1.41 15.53 0.64 1.56e-41 Malaria; LIHC cis rs9814567 0.806 rs4519744 chr3:134321523 T/C cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11190604 1.000 rs11190596 chr10:102293238 C/G cg07080220 chr10:102295463 HIF1AN 0.56 8.01 0.4 1.85e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg22528358 chr1:107598549 PRMT6 -0.66 -10.63 -0.5 5.44e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9309473 1.000 rs6724782 chr2:73679990 T/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.83 -0.35 3.84e-11 Metabolite levels; LIHC cis rs2073499 1.000 rs2073498 chr3:50369546 C/A cg08207895 chr3:50388901 TUSC4;CYB561D2 0.66 6.65 0.34 1.15e-10 Schizophrenia; LIHC cis rs1153858 0.945 rs16943246 chr15:45720597 G/A cg21132104 chr15:45694354 SPATA5L1 0.4 6.36 0.33 6.4e-10 Homoarginine levels; LIHC trans rs2739330 0.734 rs2000467 chr22:24241533 C/T cg06437703 chr8:37914619 EIF4EBP1 0.47 6.8 0.35 4.73e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs875971 0.862 rs13232191 chr7:65986648 A/G cg11764359 chr7:65958608 NA 0.78 13.62 0.59 4.71e-34 Aortic root size; LIHC cis rs2115630 0.645 rs2292463 chr15:85175750 A/G cg12501888 chr15:85177176 SCAND2 -0.46 -6.96 -0.35 1.73e-11 P wave terminal force; LIHC cis rs9517320 0.534 rs4772090 chr13:99150674 T/C cg07423050 chr13:99094983 FARP1 -0.48 -8.44 -0.42 9.22e-16 Longevity; LIHC cis rs55893317 0.505 rs56850765 chr11:10050776 C/G cg01453529 chr11:10209919 SBF2 -0.35 -6.35 -0.32 6.72e-10 Red blood cell count; LIHC cis rs797680 0.856 rs6688230 chr1:93641124 C/T cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.88 -0.3 9.71e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg01249735 chr7:156742241 NOM1 -0.43 -6.43 -0.33 4.29e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs11711311 1.000 rs11719303 chr3:113494524 A/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.13 0.44 5.9e-18 IgG glycosylation; LIHC cis rs3806843 0.932 rs2563257 chr5:140140529 A/G cg26395211 chr5:140044315 WDR55 0.4 5.97 0.31 5.79e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1005277 0.602 rs1740743 chr10:38519222 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.25 -0.32 1.22e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2075371 1.000 rs2504 chr7:133979545 A/T cg11752832 chr7:134001865 SLC35B4 0.5 7.53 0.38 4.66e-13 Mean platelet volume; LIHC cis rs10791097 0.694 rs7926167 chr11:130745045 T/C cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2997447 0.846 rs2997445 chr1:26390154 C/T cg19633962 chr1:26362018 EXTL1 -0.54 -6.07 -0.31 3.31e-9 QRS complex (12-leadsum); LIHC cis rs2760061 0.819 rs708112 chr1:228192452 G/A cg01200585 chr1:228362443 C1orf69 0.42 6.44 0.33 4.08e-10 Diastolic blood pressure; LIHC cis rs12477438 0.765 rs6740054 chr2:99576631 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.5 -0.49 1.5e-22 Chronic sinus infection; LIHC cis rs3849570 1.000 rs9817181 chr3:81827765 A/C cg07356753 chr3:81810745 GBE1 -0.63 -10.41 -0.49 3.13e-22 Waist circumference;Body mass index; LIHC cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg07092213 chr7:1199455 ZFAND2A -0.48 -7.01 -0.35 1.25e-11 Longevity;Endometriosis; LIHC cis rs7100689 0.646 rs7919380 chr10:82133380 C/T cg01528321 chr10:82214614 TSPAN14 0.78 10.38 0.49 4e-22 Post bronchodilator FEV1; LIHC cis rs4906332 1.000 rs4906327 chr14:103929039 C/T cg19000871 chr14:103996768 TRMT61A -0.47 -7.94 -0.39 2.98e-14 Coronary artery disease; LIHC cis rs78456975 1.000 rs13416881 chr2:1554808 G/A cg01028140 chr2:1542097 TPO -0.56 -6.64 -0.34 1.27e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1577917 1.000 rs12213149 chr6:86668644 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.14 -0.48 2.69e-21 Response to antipsychotic treatment; LIHC cis rs6424115 0.800 rs4649123 chr1:24197696 A/G cg15997130 chr1:24165203 NA 0.38 7.78 0.39 8.76e-14 Immature fraction of reticulocytes; LIHC trans rs6489882 0.703 rs6489864 chr12:113360025 A/G cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs3770081 1.000 rs73947314 chr2:86273116 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.45 6.19 0.32 1.71e-9 Facial emotion recognition (sad faces); LIHC cis rs807669 0.903 rs1780637 chr22:19178250 A/G cg02655711 chr22:19163373 SLC25A1 0.73 11.2 0.52 5.32e-25 Metabolite levels; LIHC cis rs6450176 0.633 rs25858 chr5:53339518 T/C ch.5.1024479R chr5:53302184 ARL15 -0.74 -13.38 -0.59 3.86e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs9517320 0.534 rs3858776 chr13:99161457 C/T cg07423050 chr13:99094983 FARP1 -0.47 -8.4 -0.41 1.2e-15 Longevity; LIHC cis rs9309473 0.528 rs7573275 chr2:73552542 G/A cg20560298 chr2:73613845 ALMS1 -0.43 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs7639513 0.545 rs9874557 chr3:12720967 A/G cg23032965 chr3:12705835 RAF1 0.58 6.35 0.32 6.93e-10 Itch intensity from mosquito bite; LIHC cis rs10911232 0.507 rs10911198 chr1:182997318 G/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -6.04 -0.31 4.06e-9 Total body bone mineral density; LIHC cis rs2073499 1.000 rs10510755 chr3:50281168 C/T cg03645007 chr3:50255295 SLC38A3 0.51 6.3 0.32 9.06e-10 Schizophrenia; LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg09367891 chr1:107599246 PRMT6 -0.69 -11.14 -0.52 8.14e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9918079 0.560 rs4557256 chr4:15626647 A/C cg24225360 chr4:15471699 CC2D2A -0.39 -6.14 -0.31 2.34e-9 Obesity-related traits; LIHC cis rs4474465 0.850 rs4245460 chr11:78258147 G/C cg27205649 chr11:78285834 NARS2 0.41 6.18 0.32 1.79e-9 Alzheimer's disease (survival time); LIHC cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg18404041 chr3:52824283 ITIH1 -0.58 -9.72 -0.47 7.08e-20 Electroencephalogram traits; LIHC cis rs1395 0.744 rs7600932 chr2:27474869 G/A cg23587288 chr2:27483067 SLC30A3 -0.35 -6.59 -0.34 1.67e-10 Blood metabolite levels; LIHC cis rs9896052 0.572 rs4078474 chr17:73489567 C/G cg25649188 chr17:73499917 CASKIN2 0.43 6.63 0.34 1.33e-10 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg00343986 chr7:65444356 GUSB 0.43 6.06 0.31 3.57e-9 Aortic root size; LIHC cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg05665937 chr4:1216051 CTBP1 0.46 6.4 0.33 5.08e-10 Obesity-related traits; LIHC cis rs34172651 0.517 rs35560136 chr16:24788915 T/A cg04756594 chr16:24857601 SLC5A11 0.57 8.38 0.41 1.39e-15 Intelligence (multi-trait analysis); LIHC cis rs6558530 0.666 rs6558523 chr8:1702504 T/C cg24391279 chr8:1708526 NA -0.35 -5.89 -0.3 9.11e-9 Systolic blood pressure; LIHC cis rs72653721 0.793 rs4713102 chr6:10968671 A/G cg13562911 chr6:11044106 ELOVL2 0.47 6.65 0.34 1.16e-10 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs13161895 1.000 rs3797763 chr5:179439516 C/T cg02702477 chr5:179499311 RNF130 -0.74 -10.27 -0.49 9.85e-22 LDL cholesterol; LIHC cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.16 0.79 6.11e-76 Prudent dietary pattern; LIHC cis rs3806843 0.966 rs10060640 chr5:140211226 G/A cg26395211 chr5:140044315 WDR55 -0.44 -6.5 -0.33 2.85e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs4555082 0.830 rs2255575 chr14:105727251 T/C cg06808227 chr14:105710500 BRF1 -0.62 -8.47 -0.42 7.3e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs9911578 1.000 rs6503870 chr17:56659018 C/T cg05425664 chr17:57184151 TRIM37 -0.58 -8.63 -0.42 2.41e-16 Intelligence (multi-trait analysis); LIHC cis rs2242116 0.727 rs10865943 chr3:46969970 T/C cg27129171 chr3:47204927 SETD2 0.53 8.59 0.42 3.06e-16 Birth weight; LIHC cis rs1568889 1.000 rs7933332 chr11:28036392 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 7.08 0.36 8.34e-12 Bipolar disorder; LIHC cis rs7772486 0.875 rs1330939 chr6:146308518 T/A cg23711669 chr6:146136114 FBXO30 0.59 10.21 0.48 1.49e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs597539 0.690 rs608810 chr11:68624118 G/C cg06028808 chr11:68637592 NA 0.44 5.73 0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs16858210 0.520 rs10460892 chr3:183546124 C/T cg25686905 chr3:183603175 PARL -0.47 -7.59 -0.38 3.06e-13 Menopause (age at onset); LIHC cis rs2625529 0.590 rs2607090 chr15:72496011 C/A cg16672083 chr15:72433130 SENP8 -0.31 -5.76 -0.3 1.88e-8 Red blood cell count; LIHC cis rs3764563 1.000 rs2283603 chr19:15731128 T/C cg20725493 chr19:15740067 CYP4F8 -0.66 -5.72 -0.3 2.35e-8 Inflammatory biomarkers; LIHC cis rs11924390 0.789 rs822366 chr3:186452490 A/G cg12454167 chr3:186435060 KNG1 0.32 7.68 0.38 1.73e-13 Adiponectin levels; LIHC cis rs12701220 0.696 rs12112029 chr7:1137889 G/A cg04025307 chr7:1156635 C7orf50 0.56 7.49 0.38 5.76e-13 Bronchopulmonary dysplasia; LIHC cis rs9291683 0.588 rs6844329 chr4:10018544 T/C cg11266682 chr4:10021025 SLC2A9 0.33 7.15 0.36 5.29e-12 Bone mineral density; LIHC cis rs1552244 0.882 rs6443276 chr3:10008905 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.73 9.98 0.47 9.6e-21 Alzheimer's disease; LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg12064134 chr16:90016061 DEF8 -0.46 -6.16 -0.32 2.08e-9 Skin colour saturation; LIHC cis rs2635047 0.967 rs1355593 chr18:44746460 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.43 5.76 0.3 1.88e-8 Educational attainment; LIHC cis rs12135062 0.851 rs2651926 chr1:3101820 C/T cg21609526 chr1:3105151 PRDM16 -0.28 -6.4 -0.33 5.1e-10 Migraine; LIHC trans rs950169 0.579 rs12912716 chr15:84664263 A/T cg00571809 chr1:3397113 ARHGEF16 0.37 6.16 0.32 2.06e-9 Schizophrenia; LIHC cis rs12142240 0.698 rs6684274 chr1:46810842 A/G cg14993813 chr1:46806288 NSUN4 0.63 5.77 0.3 1.75e-8 Menopause (age at onset); LIHC cis rs6089584 0.546 rs6061978 chr20:60615604 C/T cg06108461 chr20:60628389 TAF4 -0.62 -8.62 -0.42 2.57e-16 Body mass index; LIHC cis rs4453791 0.932 rs4315640 chr3:38923700 G/A cg02254461 chr3:39195904 CSRNP1 0.66 5.89 0.3 9.44e-9 Social communication problems; LIHC cis rs7903847 0.612 rs9887994 chr10:99159815 T/G cg06359132 chr10:99160096 RRP12 -0.4 -5.88 -0.3 9.93e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs600806 0.850 rs10745355 chr1:109951711 T/C cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.13 -0.36 6.2e-12 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06434972 chr7:44122219 POLM 0.43 6.22 0.32 1.43e-9 Pancreatic cancer; LIHC cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg07061783 chr6:25882402 NA -0.54 -6.8 -0.35 4.6e-11 Intelligence (multi-trait analysis); LIHC cis rs7833986 0.501 rs2719233 chr8:56886156 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.73 6.87 0.35 2.98e-11 Height; LIHC cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg06466757 chr4:1255808 NA 0.34 5.77 0.3 1.76e-8 Obesity-related traits; LIHC trans rs11039798 0.588 rs10160381 chr11:48599491 A/G cg15704280 chr7:45808275 SEPT13 0.57 6.35 0.32 6.75e-10 Axial length; LIHC cis rs1008375 0.932 rs6449321 chr4:17644472 A/G cg02297831 chr4:17616191 MED28 0.48 7.58 0.38 3.18e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs743757 1.000 rs9835537 chr3:50464335 T/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.45 6.37 0.33 6.19e-10 Diastolic blood pressure; LIHC cis rs10411936 0.712 rs8103486 chr19:16603107 A/G cg10248733 chr19:16607483 C19orf44;CALR3 0.54 7.17 0.36 4.65e-12 White blood cell count;Multiple sclerosis; LIHC cis rs2859741 1.000 rs1773575 chr1:37505129 T/C cg09363841 chr1:37513479 NA -0.2 -6.38 -0.33 5.6e-10 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs5758659 1.000 rs5758677 chr22:42643039 A/C cg19513890 chr22:42538836 CYP2D7P1 -0.39 -7.57 -0.38 3.56e-13 Cognitive function; LIHC cis rs17125944 0.615 rs7151643 chr14:53313661 G/C cg00686598 chr14:53173677 PSMC6 -0.84 -9.92 -0.47 1.47e-20 Alzheimer's disease (late onset); LIHC cis rs477692 1.000 rs530466 chr10:131427717 A/G cg05714579 chr10:131428358 MGMT 0.47 7.92 0.39 3.32e-14 Response to temozolomide; LIHC cis rs2576037 0.545 rs9948405 chr18:44494527 C/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.13 -0.36 5.87e-12 Personality dimensions; LIHC cis rs6951245 1.000 rs79443843 chr7:1075245 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.39 -0.45 8.66e-19 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2236918 0.710 rs2526698 chr1:242029101 T/C cg17736920 chr1:242011382 EXO1 0.41 6.07 0.31 3.43e-9 Menopause (age at onset); LIHC cis rs17685 0.697 rs28689051 chr7:75763624 G/A cg04592579 chr7:75616294 TMEM120A 0.39 6.8 0.35 4.72e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17345786 0.628 rs11718446 chr3:101552553 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.6 9.14 0.44 5.87e-18 Colonoscopy-negative controls vs population controls; LIHC cis rs589448 0.872 rs315111 chr12:69784695 G/A cg20891283 chr12:69753455 YEATS4 0.94 22.01 0.77 1.64e-67 Cerebrospinal fluid biomarker levels; LIHC cis rs9581857 0.615 rs3759435 chr13:27996813 T/G cg01674679 chr13:27998804 GTF3A -0.44 -6.41 -0.33 4.76e-10 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2795502 1.000 rs1852959 chr10:43359636 T/C cg27426351 chr10:43362370 NA 0.46 5.75 0.3 2.01e-8 Blood protein levels; LIHC cis rs12995491 0.731 rs55705009 chr2:88500718 T/G cg04511125 chr2:88470314 THNSL2 -0.47 -6.94 -0.35 2e-11 Response to metformin (IC50); LIHC cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.0 0.4 1.91e-14 Height; LIHC cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg18357526 chr6:26021779 HIST1H4A 0.4 5.95 0.31 6.78e-9 Height; LIHC cis rs13217239 0.646 rs12523820 chr6:27001502 A/G cg12292205 chr6:26970375 C6orf41 0.44 7.6 0.38 2.95e-13 Schizophrenia; LIHC cis rs9733 0.818 rs4970926 chr1:150673684 T/C cg13175981 chr1:150552382 MCL1 0.52 8.08 0.4 1.16e-14 Tonsillectomy; LIHC cis rs6952808 0.771 rs10269191 chr7:1915731 A/G cg20295408 chr7:1910781 MAD1L1 -0.53 -7.64 -0.38 2.18e-13 Bipolar disorder and schizophrenia; LIHC cis rs1538970 0.924 rs7528573 chr1:45913860 T/C cg15605315 chr1:45957053 TESK2 -0.44 -5.76 -0.3 1.91e-8 Platelet count; LIHC cis rs1707322 1.000 rs7531911 chr1:46330423 A/G cg06784218 chr1:46089804 CCDC17 0.37 6.53 0.33 2.37e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs4728302 0.574 rs7804463 chr7:133447651 T/C cg10665199 chr7:133106180 EXOC4 0.35 5.99 0.31 5.18e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs2404602 0.716 rs7164813 chr15:76708066 T/C cg23625390 chr15:77176239 SCAPER 0.37 6.02 0.31 4.47e-9 Blood metabolite levels; LIHC cis rs9611565 0.625 rs12483991 chr22:41935285 A/G cg03806693 chr22:41940476 POLR3H -0.53 -7.1 -0.36 7.4e-12 Vitiligo; LIHC cis rs35828350 1 rs35828350 chr15:85355841 G/A cg12863693 chr15:85201151 NMB 0.45 6.13 0.31 2.45e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs9916302 0.904 rs4795384 chr17:37716771 C/G cg00129232 chr17:37814104 STARD3 -0.41 -6.57 -0.33 1.92e-10 Glomerular filtration rate (creatinine); LIHC cis rs4654899 1.000 rs6689819 chr1:21472395 A/T cg08539965 chr1:21396338 EIF4G3 0.32 5.71 0.3 2.44e-8 Superior frontal gyrus grey matter volume; LIHC cis rs6089829 0.926 rs7273917 chr20:61665975 G/A cg03213289 chr20:61660250 NA 0.51 9.03 0.44 1.3e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs2522056 0.932 rs1012793 chr5:131781345 G/C cg24060327 chr5:131705240 SLC22A5 0.6 8.29 0.41 2.57e-15 Lymphocyte counts;Fibrinogen; LIHC cis rs17401966 0.867 rs61775872 chr1:10279308 T/C cg19773385 chr1:10388646 KIF1B -0.39 -7.02 -0.35 1.23e-11 Hepatocellular carcinoma; LIHC cis rs896854 0.714 rs572547 chr8:95966286 A/G cg13393036 chr8:95962371 TP53INP1 0.39 8.03 0.4 1.54e-14 Type 2 diabetes; LIHC cis rs17604090 0.529 rs10239226 chr7:29716312 C/G cg19413766 chr7:29689036 LOC646762 -0.61 -6.28 -0.32 1e-9 Facial emotion recognition;Facial emotion recognition (sad faces); LIHC cis rs6960043 0.738 rs4721400 chr7:15059906 G/A cg19272540 chr7:15055459 NA 0.26 6.75 0.34 6.51e-11 Type 2 diabetes; LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs2842992 0.830 rs2842966 chr6:160141592 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.67 11.73 0.54 6.26e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs4253772 0.720 rs4253778 chr22:46630634 C/G cg09491104 chr22:46646882 C22orf40 -0.61 -6.96 -0.35 1.76e-11 LDL cholesterol;Cholesterol, total; LIHC cis rs8067354 0.574 rs2526353 chr17:57988607 G/T cg02344993 chr17:57696989 CLTC 0.67 10.55 0.5 1.06e-22 Hemoglobin concentration; LIHC cis rs7772486 0.875 rs2777484 chr6:146334162 A/G cg05347473 chr6:146136440 FBXO30 0.35 5.72 0.3 2.27e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2932538 0.922 rs7551933 chr1:113086706 C/T cg22162597 chr1:113214053 CAPZA1 -0.63 -9.77 -0.47 4.95e-20 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs77106637 0.858 rs7109575 chr11:72463435 G/A cg03878208 chr11:72483293 STARD10 0.62 5.84 0.3 1.21e-8 Type 2 diabetes; LIHC cis rs5167 0.506 rs11669173 chr19:45492559 G/A cg13119609 chr19:45449297 APOC2 -0.23 -6.66 -0.34 1.09e-10 Blood protein levels; LIHC cis rs7727544 0.735 rs273914 chr5:131660431 A/T cg07395648 chr5:131743802 NA -0.31 -6.39 -0.33 5.53e-10 Blood metabolite levels; LIHC cis rs965469 1.000 rs6051723 chr20:3278512 C/A cg25506879 chr20:3388711 C20orf194 -0.6 -6.91 -0.35 2.43e-11 IFN-related cytopenia; LIHC cis rs7772486 0.754 rs9399561 chr6:145955687 C/G cg13319975 chr6:146136371 FBXO30 -0.39 -6.38 -0.33 5.86e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1046896 0.628 rs12452314 chr17:80723362 A/G cg08200770 chr17:80723486 TBCD -0.35 -5.83 -0.3 1.28e-8 Glycated hemoglobin levels; LIHC cis rs950169 0.580 rs2271431 chr15:85189464 A/C cg03959625 chr15:84868606 LOC388152 0.47 6.66 0.34 1.07e-10 Schizophrenia; LIHC cis rs57244997 0.725 rs11964513 chr6:162414779 C/T cg17173639 chr6:162384350 PARK2 -0.53 -6.96 -0.35 1.71e-11 Mosquito bite size; LIHC cis rs11628318 0.515 rs2093259 chr14:103145646 T/A cg12046867 chr14:103022105 NA 0.4 5.98 0.31 5.76e-9 Platelet count; LIHC cis rs7618915 0.851 rs34228726 chr3:52322797 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.41 6.49 0.33 3e-10 Bipolar disorder; LIHC trans rs62103177 0.564 rs3930042 chr18:77723843 G/A cg05926928 chr17:57297772 GDPD1 0.64 6.74 0.34 6.76e-11 Opioid sensitivity; LIHC cis rs8005677 1.000 rs2295683 chr14:23388382 A/C cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs539514 0.587 rs7320216 chr13:76332689 A/G cg04757411 chr13:76259545 LMO7 -0.4 -6.71 -0.34 8.23e-11 Type 1 diabetes; LIHC cis rs7715806 0.500 rs72633984 chr5:75005899 A/G cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs916888 0.821 rs415430 chr17:44859144 C/T cg22968622 chr17:43663579 NA -1.17 -13.21 -0.58 1.84e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7647973 1.000 rs7619789 chr3:49476263 T/C cg07636037 chr3:49044803 WDR6 0.51 6.5 0.33 2.9e-10 Menarche (age at onset); LIHC cis rs8180040 0.966 rs11711824 chr3:47468261 C/T cg16586182 chr3:47516702 SCAP -0.58 -11.28 -0.52 2.6e-25 Colorectal cancer; LIHC cis rs7772486 0.774 rs2247571 chr6:146219533 T/A cg23711669 chr6:146136114 FBXO30 0.48 8.41 0.41 1.13e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs11971779 0.680 rs6467846 chr7:139079385 G/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs7647973 0.925 rs6769821 chr3:49244657 G/A cg07636037 chr3:49044803 WDR6 0.49 5.93 0.31 7.58e-9 Menarche (age at onset); LIHC cis rs600231 0.706 rs3782091 chr11:65336483 G/T cg13974409 chr11:65292307 SCYL1 -0.38 -6.06 -0.31 3.69e-9 Bone mineral density; LIHC cis rs3796352 1.000 rs34979715 chr3:53048960 G/A cg07884673 chr3:53033167 SFMBT1 0.94 6.91 0.35 2.38e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs875971 1.000 rs2420820 chr7:66091907 T/C cg18252515 chr7:66147081 NA 0.46 6.54 0.33 2.18e-10 Aortic root size; LIHC trans rs1432089 0.773 rs72700805 chr4:171784005 T/C cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs4819052 0.807 rs7283915 chr21:46671288 T/C cg11663144 chr21:46675770 NA -0.31 -5.75 -0.3 1.98e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2153535 0.580 rs2225766 chr6:8481833 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs8017423 0.967 rs60548738 chr14:90724399 G/A cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.15e-41 Mortality in heart failure; LIHC cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.69 0.34 9.33e-11 Bipolar disorder; LIHC cis rs2204008 0.713 rs12366709 chr12:38210179 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs1577917 0.629 rs7761762 chr6:86205968 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.43 7.76 0.39 9.94e-14 Response to antipsychotic treatment; LIHC cis rs7613875 0.620 rs2526747 chr3:50082914 C/G cg05623727 chr3:50126028 RBM5 0.35 6.04 0.31 4.08e-9 Body mass index; LIHC cis rs67478160 0.619 rs12885018 chr14:104273812 A/G cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.48 -0.37 6.33e-13 Schizophrenia; LIHC cis rs12744310 1.000 rs68132196 chr1:41770620 C/A cg03962019 chr1:41807865 NA 0.41 6.53 0.33 2.44e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6933660 0.800 rs6930557 chr6:151755806 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.62 10.12 0.48 3.06e-21 Menarche (age at onset); LIHC cis rs4727027 0.933 rs757738 chr7:148872351 T/G cg23583168 chr7:148888333 NA -0.74 -10.48 -0.49 1.83e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2153535 0.560 rs9379214 chr6:8480870 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs4808199 0.947 rs2163804 chr19:19575965 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.43 6.18 0.32 1.86e-9 Nonalcoholic fatty liver disease; LIHC cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg13047869 chr3:10149882 C3orf24 -0.52 -6.78 -0.34 5.23e-11 Alzheimer's disease; LIHC trans rs10506458 0.834 rs17738403 chr12:63389200 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.74 -10.43 -0.49 2.72e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs116095464 0.558 rs10057492 chr5:239503 T/C cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.78e-52 Breast cancer; LIHC cis rs8103278 0.740 rs2341097 chr19:46268902 C/T cg11657440 chr19:46296263 DMWD -0.54 -8.47 -0.42 7.27e-16 Coronary artery disease; LIHC cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg20887711 chr4:1340912 KIAA1530 0.45 6.02 0.31 4.48e-9 Obesity-related traits; LIHC cis rs7582180 0.764 rs11689439 chr2:100925399 T/C cg14675211 chr2:100938903 LONRF2 0.51 8.05 0.4 1.42e-14 Intelligence (multi-trait analysis); LIHC cis rs9479482 1.000 rs5006620 chr6:150336665 C/T cg25797454 chr6:150327115 RAET1K 0.32 5.75 0.3 1.96e-8 Alopecia areata; LIHC cis rs11628318 0.614 rs72635192 chr14:103128646 C/T cg12046867 chr14:103022105 NA 0.5 7.24 0.36 3.01e-12 Platelet count; LIHC cis rs9457247 0.905 rs377232 chr6:167409638 C/A cg12798992 chr6:167411361 FGFR1OP 0.62 10.42 0.49 2.99e-22 Crohn's disease; LIHC cis rs1707322 1.000 rs785493 chr1:46584859 A/G cg03146154 chr1:46216737 IPP -0.46 -7.28 -0.37 2.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1670533 1.000 rs7669622 chr4:1058659 A/G cg27284194 chr4:1044797 NA 0.6 8.98 0.44 1.83e-17 Recombination rate (females); LIHC cis rs1707322 0.721 rs12043945 chr1:46106922 T/A cg03146154 chr1:46216737 IPP 0.57 9.9 0.47 1.78e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2422052 1.000 rs2422052 chr2:118651764 G/C cg22545206 chr2:118617499 NA 0.36 6.11 0.31 2.76e-9 Mosquito bite size; LIHC cis rs2074193 0.826 rs215349 chr12:47734467 A/T cg02516419 chr12:47771422 NA 0.42 6.61 0.34 1.49e-10 Migraine with aura; LIHC cis rs8067354 0.789 rs4622571 chr17:57884397 T/A cg02344993 chr17:57696989 CLTC 0.56 9.19 0.44 4.04e-18 Hemoglobin concentration; LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg26354017 chr1:205819088 PM20D1 0.66 9.65 0.46 1.17e-19 Menarche (age at onset); LIHC cis rs9733 0.519 rs1336899 chr1:150678910 T/C cg15448220 chr1:150897856 SETDB1 0.43 6.77 0.34 5.77e-11 Tonsillectomy; LIHC trans rs11037575 0.966 rs2863002 chr11:43714768 C/T cg11141497 chr11:6633666 TAF10 -0.41 -6.07 -0.31 3.37e-9 Neuroblastoma; LIHC cis rs2404602 0.583 rs2469542 chr15:76557476 A/G cg03037974 chr15:76606532 NA -0.84 -20.52 -0.74 1.44e-61 Blood metabolite levels; LIHC cis rs35110281 0.777 rs7276215 chr21:44990697 A/G cg21573476 chr21:45109991 RRP1B -0.59 -11.07 -0.51 1.51e-24 Mean corpuscular volume; LIHC cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.64 -0.46 1.28e-19 Initial pursuit acceleration; LIHC cis rs11031096 0.683 rs10835729 chr11:4210847 T/C cg18678763 chr11:4115507 RRM1 -0.41 -5.97 -0.31 6e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs79839061 0.610 rs11733713 chr4:869169 A/G cg07828340 chr4:882639 GAK 0.81 6.82 0.35 4.16e-11 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.752 rs11211168 chr1:46163647 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.19 0.36 4.14e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs72627123 0.656 rs75646425 chr14:74529433 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 5.78 0.3 1.69e-8 Morning vs. evening chronotype; LIHC cis rs10078 0.571 rs890973 chr5:471494 T/C cg24955955 chr5:415729 AHRR 0.6 11.32 0.52 1.94e-25 Fat distribution (HIV); LIHC cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs796364 0.806 rs12619136 chr2:200910347 C/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs1559088 0.948 rs12610266 chr19:33581237 C/G cg17764715 chr19:33622953 WDR88 -0.45 -6.48 -0.33 3.11e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2074038 1.000 rs2074038 chr11:44087989 G/T cg00452199 chr11:44088257 ACCS -0.53 -6.77 -0.34 5.64e-11 IgA nephropathy; LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg22903471 chr2:27725779 GCKR -0.5 -8.7 -0.43 1.47e-16 Total body bone mineral density; LIHC cis rs2806561 0.704 rs856510 chr1:23524407 A/C cg11953164 chr1:23521307 HTR1D 0.29 5.78 0.3 1.68e-8 Height; LIHC cis rs6138458 0.626 rs6138473 chr20:25012155 A/G cg26195577 chr20:24973756 C20orf3 -0.75 -9.46 -0.46 5.05e-19 Blood protein levels; LIHC cis rs3736485 0.903 rs4545756 chr15:51877790 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11098499 0.542 rs10440343 chr4:120309787 G/C cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs611744 0.647 rs1448151 chr8:109276283 C/A cg21045802 chr8:109455806 TTC35 0.59 10.34 0.49 5.45e-22 Dupuytren's disease; LIHC cis rs1552244 0.608 rs2075310 chr3:10067651 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.17 -0.48 2.14e-21 Alzheimer's disease; LIHC cis rs7429990 0.901 rs7374482 chr3:48168390 A/G cg11946769 chr3:48343235 NME6 -0.47 -6.24 -0.32 1.28e-9 Educational attainment (years of education); LIHC cis rs2832077 0.505 rs9305386 chr21:30386751 A/G cg20220242 chr21:30392188 RWDD2B 0.48 6.59 0.34 1.68e-10 Cognitive test performance; LIHC cis rs9811920 0.599 rs61148087 chr3:99539891 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 7.1 0.36 7.26e-12 Axial length; LIHC trans rs1814175 0.715 rs1722007 chr11:49897319 T/C cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs597539 0.652 rs602364 chr11:68662167 C/T cg04772025 chr11:68637568 NA 0.46 6.13 0.31 2.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs769267 0.930 rs2315022 chr19:19413381 A/G cg21559469 chr19:19431446 KIAA0892;SF4 0.42 5.9 0.3 8.68e-9 Tonsillectomy; LIHC cis rs1401999 0.724 rs1016752 chr3:183665062 C/G cg05044414 chr3:183734942 ABCC5 -0.36 -6.01 -0.31 4.65e-9 Anterior chamber depth; LIHC cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg05564831 chr3:52568323 NT5DC2 0.37 5.91 0.3 8.46e-9 Bipolar disorder; LIHC cis rs4319547 0.656 rs10744209 chr12:122931568 G/A cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.41 -0.37 1.03e-12 Body mass index; LIHC cis rs7223966 1.000 rs8066719 chr17:61825764 C/T cg05941027 chr17:61774174 LIMD2 0.35 7.43 0.37 8.8e-13 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18931685 chr19:45505298 RELB 0.43 6.12 0.31 2.62e-9 Pancreatic cancer; LIHC cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg23205692 chr1:25664452 TMEM50A -0.37 -5.97 -0.31 6.1e-9 Erythrocyte sedimentation rate; LIHC cis rs1559088 1.000 rs8106453 chr19:33557412 C/T cg17764715 chr19:33622953 WDR88 0.41 5.79 0.3 1.61e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs8072100 0.967 rs8078880 chr17:45676526 G/C cg08085267 chr17:45401833 C17orf57 0.39 5.86 0.3 1.06e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7818688 0.697 rs11781397 chr8:95974506 G/T cg16049864 chr8:95962084 TP53INP1 0.62 6.78 0.34 5.18e-11 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs67478160 0.619 rs11160759 chr14:104231542 C/T cg08213375 chr14:104286397 PPP1R13B 0.66 12.95 0.57 1.74e-31 Schizophrenia; LIHC cis rs7613875 0.620 rs7430334 chr3:50078221 T/C cg05623727 chr3:50126028 RBM5 -0.34 -5.82 -0.3 1.38e-8 Body mass index; LIHC cis rs7927771 0.524 rs7116346 chr11:47883880 G/A cg20307385 chr11:47447363 PSMC3 -0.65 -9.77 -0.47 4.92e-20 Subjective well-being; LIHC cis rs72781680 0.948 rs72796385 chr2:24170360 T/A cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs2637266 0.935 rs2583058 chr10:78396018 T/A cg18941641 chr10:78392320 NA 0.29 6.36 0.33 6.43e-10 Pulmonary function; LIHC trans rs11039798 0.920 rs116109043 chr11:48976940 C/T cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC cis rs4474465 0.915 rs11237505 chr11:78171261 A/G cg27205649 chr11:78285834 NARS2 -0.38 -5.88 -0.3 9.86e-9 Alzheimer's disease (survival time); LIHC cis rs7312933 0.607 rs7965392 chr12:42540280 G/A cg17420585 chr12:42539391 GXYLT1 -0.37 -5.83 -0.3 1.29e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6061231 0.654 rs2427322 chr20:60979370 T/C cg24112000 chr20:60950667 NA -0.55 -8.53 -0.42 4.75e-16 Colorectal cancer; LIHC cis rs9649213 0.614 rs9640655 chr7:98017099 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.56 -9.8 -0.47 3.81e-20 Prostate cancer (SNP x SNP interaction); LIHC cis rs477692 1.000 rs531572 chr10:131427569 A/G cg19680672 chr10:131412579 MGMT 0.43 6.6 0.34 1.56e-10 Response to temozolomide; LIHC cis rs4474465 1.000 rs10899502 chr11:78141021 C/T cg02023728 chr11:77925099 USP35 0.34 6.02 0.31 4.41e-9 Alzheimer's disease (survival time); LIHC cis rs7772486 0.686 rs1292334 chr6:145968288 A/G cg23711669 chr6:146136114 FBXO30 0.71 13.04 0.58 7.81e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs35146811 0.806 rs1534310 chr7:99699169 A/T cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.43 6.17 0.32 1.96e-9 Coronary artery disease; LIHC cis rs7666738 0.830 rs62318472 chr4:98926030 G/A cg05340658 chr4:99064831 C4orf37 0.71 12.97 0.57 1.46e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs372883 0.600 rs1236460 chr21:30615513 G/A cg24692254 chr21:30365293 RNF160 -0.51 -6.39 -0.33 5.41e-10 Pancreatic cancer; LIHC cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.3 -6.01 -0.31 4.86e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7619427 0.544 rs9866639 chr3:43990450 G/A cg24966902 chr3:44043705 NA 0.44 6.67 0.34 1.03e-10 Schizophrenia; LIHC cis rs3749237 0.557 rs7631908 chr3:49425707 T/G cg07636037 chr3:49044803 WDR6 0.5 7.53 0.38 4.44e-13 Resting heart rate; LIHC cis rs10905065 0.965 rs10795541 chr10:5811954 A/G cg11519256 chr10:5708881 ASB13 -0.43 -5.8 -0.3 1.53e-8 Menopause (age at onset); LIHC cis rs2625529 0.824 rs12592044 chr15:72419115 A/G cg16672083 chr15:72433130 SENP8 -0.3 -5.72 -0.3 2.38e-8 Red blood cell count; LIHC cis rs7715806 0.500 rs3797581 chr5:75002895 G/T cg19683494 chr5:74908142 NA 0.56 6.67 0.34 1.05e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2120019 1.000 rs7173833 chr15:75369618 C/T cg06012730 chr15:75315579 PPCDC -0.32 -6.14 -0.32 2.25e-9 Blood trace element (Zn levels); LIHC cis rs8056893 0.714 rs1530643 chr16:68396092 T/C cg02226672 chr16:68398533 SMPD3 0.42 5.98 0.31 5.77e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs12701220 0.520 rs7803208 chr7:1162084 C/T cg01324507 chr7:1177794 C7orf50 0.51 6.66 0.34 1.07e-10 Bronchopulmonary dysplasia; LIHC cis rs6545883 0.929 rs2421203 chr2:61669248 C/A cg14146966 chr2:61757674 XPO1 0.46 8.07 0.4 1.18e-14 Tuberculosis; LIHC cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg12292205 chr6:26970375 C6orf41 0.45 7.79 0.39 8.08e-14 Schizophrenia; LIHC cis rs4700695 0.925 rs10069614 chr5:65396530 A/C cg21114390 chr5:65439923 SFRS12 -0.44 -5.89 -0.3 9.12e-9 Facial morphology (factor 19); LIHC cis rs7940866 0.874 rs11222406 chr11:130814093 A/G cg12179176 chr11:130786555 SNX19 0.55 7.93 0.39 3.19e-14 Schizophrenia; LIHC cis rs9916302 0.851 rs12936996 chr17:37665554 A/G cg03013999 chr17:37608204 MED1 -0.35 -5.77 -0.3 1.77e-8 Glomerular filtration rate (creatinine); LIHC cis rs7769051 1.000 rs73554431 chr6:133129922 T/G cg22852734 chr6:133119734 C6orf192 0.9 9.24 0.45 2.74e-18 Type 2 diabetes nephropathy; LIHC trans rs561341 1.000 rs535151 chr17:30317405 C/T cg20587970 chr11:113659929 NA -0.64 -7.41 -0.37 9.95e-13 Hip circumference adjusted for BMI; LIHC cis rs2836974 0.583 rs9981884 chr21:40585633 G/A cg11890956 chr21:40555474 PSMG1 0.62 9.16 0.44 5e-18 Cognitive function; LIHC trans rs7395662 0.500 rs10838984 chr11:48640485 C/T cg15704280 chr7:45808275 SEPT13 -0.49 -7.36 -0.37 1.39e-12 HDL cholesterol; LIHC cis rs2439831 0.867 rs2412779 chr15:43655927 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.31 0.52 2.11e-25 Lung cancer in ever smokers; LIHC cis rs9309473 0.554 rs4330127 chr2:73581320 A/T cg20560298 chr2:73613845 ALMS1 -0.42 -6.51 -0.33 2.61e-10 Metabolite levels; LIHC cis rs2380220 0.808 rs2380224 chr6:95895553 C/T cg15832292 chr6:96025679 MANEA -0.63 -7.24 -0.36 2.96e-12 Behavioural disinhibition (generation interaction); LIHC cis rs11690935 0.550 rs6718013 chr2:172869185 A/G cg13550731 chr2:172543902 DYNC1I2 0.44 6.81 0.35 4.29e-11 Schizophrenia; LIHC cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg12310025 chr6:25882481 NA -1.07 -16.57 -0.67 1.09e-45 Uric acid levels; LIHC cis rs1728785 1.000 rs4783656 chr16:68580722 C/T cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs7000551 0.700 rs2461491 chr8:22361252 C/T cg12081754 chr8:22256438 SLC39A14 -0.43 -7.27 -0.37 2.4e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs6582630 0.502 rs11520279 chr12:38360871 A/G cg26384229 chr12:38710491 ALG10B 0.57 7.88 0.39 4.37e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs8062405 1.000 rs3088215 chr16:28853996 A/C cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6429082 0.509 rs35446932 chr1:235523480 C/T cg26050004 chr1:235667680 B3GALNT2 0.43 6.43 0.33 4.32e-10 Adiposity; LIHC cis rs10847980 0.590 rs12299742 chr12:123323357 T/G cg25930673 chr12:123319894 HIP1R 1.04 11.55 0.53 2.78e-26 Adiponectin levels; LIHC cis rs8180040 1.000 rs807931 chr3:47389317 C/T cg16586182 chr3:47516702 SCAP -0.55 -10.24 -0.48 1.19e-21 Colorectal cancer; LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.8 -0.3 1.55e-8 Total body bone mineral density; LIHC cis rs35883536 0.647 rs10875328 chr1:101169328 C/T cg14515779 chr1:101123966 NA 0.55 7.81 0.39 7.03e-14 Monocyte count; LIHC cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.85e-26 Platelet count; LIHC cis rs9378688 1.000 rs12661136 chr6:2227239 C/A cg12303981 chr6:2244766 GMDS -0.49 -6.22 -0.32 1.48e-9 Caudate nucleus volume; LIHC cis rs7223966 1.000 rs16947014 chr17:61719032 C/T cg05941027 chr17:61774174 LIMD2 0.34 6.92 0.35 2.2e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2112347 0.502 rs34339 chr5:74931333 G/T cg02573091 chr5:74908125 NA -0.6 -7.1 -0.36 7.22e-12 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg17428748 chr7:158741438 NA -0.37 -6.68 -0.34 9.73e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12971120 0.891 rs4891557 chr18:72170299 C/T cg25817165 chr18:72167213 CNDP2 -0.71 -12.45 -0.56 1.31e-29 Refractive error; LIHC cis rs17253792 0.915 rs75862063 chr14:56177769 G/T cg01858014 chr14:56050164 KTN1 -0.75 -7.41 -0.37 9.7e-13 Putamen volume; LIHC cis rs7961581 0.748 rs1072672 chr12:71597470 A/C cg05756094 chr12:71608604 NA 0.41 6.62 0.34 1.36e-10 Type 2 diabetes; LIHC cis rs34172651 0.517 rs12927710 chr16:24790282 A/C cg04756594 chr16:24857601 SLC5A11 0.58 8.36 0.41 1.56e-15 Intelligence (multi-trait analysis); LIHC cis rs9921222 0.500 rs11645742 chr16:367516 C/T cg26944245 chr16:421049 TMEM8A;MRPL28 0.45 7.42 0.37 9.57e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg06481639 chr22:41940642 POLR3H -0.7 -6.94 -0.35 1.97e-11 Vitiligo; LIHC cis rs1434579 0.966 rs12151338 chr19:44933947 G/A cg15540054 chr19:45004280 ZNF180 0.58 7.82 0.39 6.58e-14 Tuberculosis; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg10755058 chr3:40428713 ENTPD3 0.41 6.99 0.35 1.49e-11 Renal cell carcinoma; LIHC cis rs10089 1.000 rs4836361 chr5:127459991 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.05e-11 Ileal carcinoids; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16739247 chr1:76252438 SNORD45C;SNORD45A;RABGGTB 0.45 6.91 0.35 2.38e-11 Pancreatic cancer; LIHC cis rs7267979 0.966 rs910996 chr20:25264196 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.75 0.34 6.2e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2742417 0.603 rs2742398 chr3:45759036 A/G cg04837898 chr3:45731254 SACM1L -0.53 -8.99 -0.44 1.73e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs9611565 0.559 rs6002408 chr22:41967870 C/T cg06634786 chr22:41940651 POLR3H -0.61 -6.53 -0.33 2.33e-10 Vitiligo; LIHC cis rs8005677 1.000 rs1956881 chr14:23394069 A/C cg25600027 chr14:23388339 RBM23 -0.42 -6.08 -0.31 3.15e-9 Cognitive ability (multi-trait analysis); LIHC cis rs1577917 0.839 rs9450333 chr6:86519755 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -7.95 -0.4 2.66e-14 Response to antipsychotic treatment; LIHC trans rs4332037 0.552 rs11773627 chr7:2002733 A/G cg11693508 chr17:37793320 STARD3 0.66 6.81 0.35 4.27e-11 Bipolar disorder; LIHC cis rs244293 0.965 rs2529505 chr17:53206808 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs6120849 0.754 rs6088686 chr20:33623437 C/T cg24642439 chr20:33292090 TP53INP2 0.65 7.05 0.36 9.65e-12 Protein C levels; LIHC cis rs7572733 0.515 rs13408411 chr2:198825462 G/A cg10820045 chr2:198174542 NA 0.48 7.4 0.37 1.09e-12 Dermatomyositis; LIHC cis rs10876993 0.928 rs2640637 chr12:58077586 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.25 -0.32 1.23e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.04 13.11 0.58 4.22e-32 Alzheimer's disease; LIHC cis rs4917300 0.605 rs10108708 chr8:143102886 A/G cg25363559 chr8:143086065 NA -0.28 -8.43 -0.41 9.45e-16 Amyotrophic lateral sclerosis; LIHC cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.73 0.39 1.2e-13 Electroencephalogram traits; LIHC cis rs7071206 0.947 rs1877998 chr10:79411740 C/T cg07817648 chr10:79422355 NA -0.33 -6.94 -0.35 2.02e-11 Bone mineral density; LIHC cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg03264133 chr6:25882463 NA -0.59 -8.43 -0.41 9.93e-16 Blood metabolite levels; LIHC cis rs2153535 0.580 rs1577468 chr6:8444266 C/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs950169 0.922 rs4842940 chr15:84831225 C/T cg03959625 chr15:84868606 LOC388152 -0.44 -6.47 -0.33 3.31e-10 Schizophrenia; LIHC cis rs7296418 0.663 rs4553407 chr12:123750748 G/C cg00376283 chr12:123451042 ABCB9 0.63 10.29 0.49 8.51e-22 Platelet count; LIHC cis rs12478296 1.000 rs56102931 chr2:243039936 A/G cg18898632 chr2:242989856 NA -0.58 -7.84 -0.39 5.85e-14 Obesity-related traits; LIHC cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg07424592 chr7:64974309 NA 0.82 9.53 0.46 2.98e-19 Diabetic kidney disease; LIHC cis rs72627123 0.656 rs11159064 chr14:74614743 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 -0.84 -7.95 -0.39 2.79e-14 Morning vs. evening chronotype; LIHC cis rs9457247 0.663 rs9295384 chr6:167448113 T/A cg12798992 chr6:167411361 FGFR1OP 0.45 6.99 0.35 1.46e-11 Crohn's disease; LIHC cis rs4803468 1.000 rs4803469 chr19:41922775 A/C cg14132834 chr19:41945861 ATP5SL -0.44 -6.52 -0.33 2.5e-10 Height; LIHC cis rs798554 1.000 rs798536 chr7:2766383 G/A cg13628971 chr7:2884303 GNA12 0.54 7.8 0.39 7.56e-14 Height; LIHC cis rs7777754 0.512 rs3757472 chr7:50537983 A/C cg14593290 chr7:50529359 DDC -0.53 -8.94 -0.44 2.55e-17 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC cis rs4474465 0.688 rs7945812 chr11:78280509 T/C cg02023728 chr11:77925099 USP35 -0.33 -5.94 -0.31 6.92e-9 Alzheimer's disease (survival time); LIHC cis rs1670533 0.872 rs6854793 chr4:1055768 T/C cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.38e-17 Recombination rate (females); LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg11494091 chr17:61959527 GH2 0.44 8.13 0.4 7.79e-15 Prudent dietary pattern; LIHC cis rs2228479 0.850 rs2190808 chr16:89840856 C/T cg04013166 chr16:89971882 TCF25 0.53 6.67 0.34 1.04e-10 Skin colour saturation; LIHC cis rs2072499 1.000 rs2253809 chr1:156172125 T/C cg24450063 chr1:156163899 SLC25A44 1.06 18.21 0.7 2.78e-52 Testicular germ cell tumor; LIHC cis rs6570726 0.791 rs1280275 chr6:145892402 C/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.45 -0.33 3.8e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1144333 1.000 rs112401426 chr1:76466103 T/A cg03433033 chr1:76189801 ACADM 0.51 7.5 0.38 5.47e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs9640161 0.830 rs6722 chr7:150068933 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.33 -0.41 2.02e-15 Blood protein levels;Circulating chemerin levels; LIHC trans rs12752401 1.000 rs67551785 chr1:102978472 T/C cg17681729 chr19:740608 PALM 0.46 6.49 0.33 2.99e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs3099143 0.803 rs28618274 chr15:77220243 C/T cg21673338 chr15:77095150 SCAPER -0.49 -7.06 -0.36 9.46e-12 Recalcitrant atopic dermatitis; LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg13409248 chr3:40428643 ENTPD3 0.48 7.83 0.39 6.01e-14 Renal cell carcinoma; LIHC cis rs7635838 0.819 rs6776159 chr3:11519324 A/G cg00170343 chr3:11313890 ATG7 0.41 6.41 0.33 4.91e-10 HDL cholesterol; LIHC cis rs9902453 0.765 rs2467334 chr17:28135508 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC trans rs875971 1.000 rs1167612 chr7:65567976 C/A cg10756647 chr7:56101905 PSPH -0.45 -6.34 -0.32 7.36e-10 Aortic root size; LIHC trans rs6600671 1.000 rs11249351 chr1:121171942 G/A cg09829573 chr1:144692074 NBPF9 -0.45 -8.23 -0.41 4.12e-15 Hip geometry; LIHC cis rs11098499 0.644 rs6855918 chr4:120546299 C/T cg09307838 chr4:120376055 NA 0.67 10.34 0.49 5.7e-22 Corneal astigmatism; LIHC cis rs644799 1.000 rs563653 chr11:95561488 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7618501 0.699 rs9821675 chr3:49902544 A/G cg24110177 chr3:50126178 RBM5 -0.52 -8.0 -0.4 1.95e-14 Intelligence (multi-trait analysis); LIHC cis rs921968 0.643 rs659185 chr2:219335935 C/T cg02985541 chr2:219472218 PLCD4 0.47 8.81 0.43 6.64e-17 Mean corpuscular hemoglobin concentration; LIHC cis rs797680 0.856 rs2031225 chr1:93786714 A/G cg15093775 chr1:93646470 TMED5;CCDC18 0.35 6.24 0.32 1.32e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs11098499 1.000 rs11726229 chr4:120211580 C/T cg09307838 chr4:120376055 NA 0.72 10.66 0.5 4.1000000000000003e-23 Corneal astigmatism; LIHC cis rs600806 0.778 rs11101961 chr1:110008813 T/C cg10127483 chr1:110009974 SYPL2 0.48 6.06 0.31 3.53e-9 Intelligence (multi-trait analysis); LIHC cis rs6840360 1.000 rs6841783 chr4:152598876 C/G cg22705602 chr4:152727874 NA -0.31 -6.53 -0.33 2.39e-10 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg24693881 chr1:107596107 NA -0.54 -9.63 -0.46 1.38e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4660306 0.744 rs11211115 chr1:45926438 A/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.62 6.73 0.34 7.06e-11 Homocysteine levels; LIHC cis rs932287 0.505 rs2742536 chr11:8909816 G/C cg21881798 chr11:8931708 C11orf17;ST5 -0.5 -9.02 -0.44 1.39e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs9790314 1.000 rs189270 chr3:161063504 T/C cg04691961 chr3:161091175 C3orf57 -0.41 -6.5 -0.33 2.92e-10 Morning vs. evening chronotype; LIHC cis rs9596863 0.898 rs35863857 chr13:54372546 A/G ch.13.53330881F chr13:54432880 NA 0.43 5.74 0.3 2.1e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 6.7 0.34 8.71e-11 Bipolar disorder; LIHC cis rs11690935 0.851 rs6433319 chr2:172830953 C/T cg13550731 chr2:172543902 DYNC1I2 -0.45 -7.41 -0.37 9.79e-13 Schizophrenia; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg04234412 chr22:24373322 LOC391322 -0.68 -10.24 -0.48 1.24e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2737618 0.630 rs2821328 chr1:200082051 G/A cg21825944 chr1:200113062 NR5A2 -0.45 -7.74 -0.39 1.11e-13 Uric acid levels; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg14671364 chr1:107599128 PRMT6 0.46 6.62 0.34 1.38e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1801251 0.964 rs6748027 chr2:233629552 T/C cg25237894 chr2:233734115 C2orf82 0.57 11.15 0.52 7.58e-25 Coronary artery disease; LIHC cis rs7212590 0.655 rs8072050 chr17:58010972 G/A cg10252138 chr17:58120427 NA -0.58 -5.87 -0.3 1.01e-8 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs637571 0.546 rs11227311 chr11:65585257 C/A cg26695010 chr11:65641043 EFEMP2 0.46 6.48 0.33 3.29e-10 Eosinophil percentage of white cells; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg08280861 chr8:58055591 NA 0.51 6.39 0.33 5.56e-10 Developmental language disorder (linguistic errors); LIHC cis rs4631830 0.863 rs2611507 chr10:51518673 T/C cg20129853 chr10:51489980 NA -0.43 -9.35 -0.45 1.15e-18 Prostate-specific antigen levels; LIHC cis rs6429082 0.597 rs6683978 chr1:235541425 A/G cg26050004 chr1:235667680 B3GALNT2 -0.47 -7.04 -0.36 1.06e-11 Adiposity; LIHC cis rs9549328 0.921 rs9549623 chr13:113640293 G/A cg00071026 chr13:113650936 MCF2L -0.37 -5.87 -0.3 1.02e-8 Systolic blood pressure; LIHC cis rs7432375 0.901 rs4521165 chr3:136369710 T/C cg21827317 chr3:136751795 NA -0.44 -5.85 -0.3 1.14e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs9733 0.536 rs10888385 chr1:150574302 T/C cg18016565 chr1:150552671 MCL1 -0.55 -11.04 -0.51 1.96e-24 Tonsillectomy; LIHC cis rs3020736 0.500 rs764481 chr22:42518426 G/A cg15557168 chr22:42548783 NA 0.43 6.78 0.34 5.3e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs1371867 0.846 rs1660317 chr8:101333252 G/T cg06636551 chr8:101224915 SPAG1 -0.49 -9.1 -0.44 7.79e-18 Atrioventricular conduction; LIHC trans rs916888 0.779 rs199528 chr17:44843136 C/T cg26692224 chr17:62915920 LRRC37A3 -0.68 -6.29 -0.32 9.66e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2073300 0.609 rs6137948 chr20:23416845 G/A cg12062639 chr20:23401060 NAPB 1.04 13.43 0.59 2.67e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs801193 0.660 rs4610622 chr7:66224497 T/C cg18876405 chr7:65276391 NA 0.33 6.05 0.31 3.83e-9 Aortic root size; LIHC cis rs9303280 0.806 rs12232497 chr17:38040119 T/C cg11212589 chr17:38028394 ZPBP2 0.35 7.16 0.36 4.89e-12 Self-reported allergy; LIHC cis rs3806843 0.966 rs4141841 chr5:140203432 C/T cg26395211 chr5:140044315 WDR55 -0.44 -6.56 -0.33 2.03e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs3093024 0.839 rs968334 chr6:167526096 T/C cg07741184 chr6:167504864 NA -0.3 -7.08 -0.36 8.21e-12 Rheumatoid arthritis; LIHC cis rs12477438 0.501 rs13033012 chr2:99795149 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs2576037 0.526 rs2510444 chr18:44376849 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.63 9.92 0.47 1.48e-20 Personality dimensions; LIHC cis rs10769945 0.538 rs739906 chr11:1980568 T/C cg23202291 chr11:1979235 NA -0.47 -7.04 -0.36 1.07e-11 DNA methylation (variation); LIHC cis rs12586317 0.547 rs112138868 chr14:35444385 C/T cg16230307 chr14:35515116 FAM177A1 0.77 12.8 0.57 6.22e-31 Psoriasis; LIHC cis rs2197308 0.765 rs11182964 chr12:37935052 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs9911578 0.835 rs9904993 chr17:56468569 G/T cg05425664 chr17:57184151 TRIM37 0.57 8.24 0.41 3.74e-15 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07498874 chr1:110577829 FAM40A -0.42 -6.14 -0.32 2.32e-9 Pancreatic cancer; LIHC cis rs7582720 0.945 rs72934583 chr2:204009057 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4474465 1.000 rs10899522 chr11:78190763 C/G cg27205649 chr11:78285834 NARS2 0.4 6.05 0.31 3.89e-9 Alzheimer's disease (survival time); LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 11.74 0.54 5.67e-27 Prudent dietary pattern; LIHC cis rs798554 0.600 rs2679259 chr7:2885322 C/G cg13628971 chr7:2884303 GNA12 0.48 8.42 0.41 1.06e-15 Height; LIHC cis rs919433 0.963 rs12618612 chr2:198171058 G/T cg03934865 chr2:198174659 NA -0.57 -9.1 -0.44 7.61e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs67981189 0.634 rs2526875 chr14:71378360 G/C cg15816911 chr14:71606274 NA -0.39 -6.11 -0.31 2.67e-9 Schizophrenia; LIHC cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg02290350 chr8:58132656 NA 0.47 9.31 0.45 1.6e-18 Developmental language disorder (linguistic errors); LIHC cis rs870825 0.616 rs10022818 chr4:185619282 A/G cg04058563 chr4:185651563 MLF1IP 0.65 6.94 0.35 2.01e-11 Blood protein levels; LIHC cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg03517284 chr6:25882590 NA -0.48 -7.35 -0.37 1.48e-12 Height; LIHC cis rs4660306 1.000 rs11211132 chr1:45990516 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC -0.55 -6.67 -0.34 1.02e-10 Homocysteine levels; LIHC cis rs4819052 0.851 rs2838849 chr21:46671027 A/G cg22633049 chr21:46681294 NA -0.37 -6.34 -0.32 7.23e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2727020 0.513 rs10839307 chr11:49609843 A/C cg18944383 chr4:111397179 ENPEP 0.25 6.25 0.32 1.23e-9 Coronary artery disease; LIHC cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg24531977 chr5:56204891 C5orf35 -0.64 -9.22 -0.45 3.1e-18 Initial pursuit acceleration; LIHC cis rs7666738 0.546 rs1456207 chr4:98676911 G/A cg05340658 chr4:99064831 C4orf37 0.49 6.26 0.32 1.16e-9 Colonoscopy-negative controls vs population controls; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19455953 chr2:207630073 FASTKD2;MDH1B 0.4 6.47 0.33 3.43e-10 Pancreatic cancer; LIHC trans rs1005277 0.522 rs9418276 chr10:37940116 G/T cg27523141 chr10:43048294 ZNF37B 0.37 6.51 0.33 2.74e-10 Extrinsic epigenetic age acceleration; LIHC cis rs72781680 0.768 rs56339558 chr2:24125234 G/A cg08917208 chr2:24149416 ATAD2B 0.62 6.15 0.32 2.15e-9 Lymphocyte counts; LIHC cis rs11758351 1.000 rs41266807 chr6:26199822 A/G cg03854865 chr6:26224070 HIST1H3E 0.64 7.12 0.36 6.24e-12 Gout;Renal underexcretion gout; LIHC cis rs1843834 0.898 rs4674936 chr2:225553731 C/T cg22509189 chr2:225307070 NA -0.55 -6.81 -0.35 4.28e-11 IgE levels in asthmatics (D.p. specific); LIHC cis rs1152591 0.811 rs1255984 chr14:64654431 C/T cg23250157 chr14:64679961 SYNE2 -0.41 -5.72 -0.3 2.33e-8 Atrial fibrillation; LIHC cis rs11673344 0.730 rs1644641 chr19:37462139 A/G cg27390819 chr19:37464633 NA -0.53 -6.35 -0.32 6.69e-10 Obesity-related traits; LIHC cis rs2404602 0.692 rs2120108 chr15:76869929 G/T cg03037974 chr15:76606532 NA -0.73 -14.36 -0.61 6.49e-37 Blood metabolite levels; LIHC cis rs2404602 0.622 rs4886506 chr15:77207277 G/T cg23625390 chr15:77176239 SCAPER 0.53 9.09 0.44 7.99e-18 Blood metabolite levels; LIHC trans rs9513675 0.816 rs7994234 chr13:100493620 A/C cg27600510 chr10:36137546 NA 0.22 6.08 0.31 3.24e-9 Obesity-related traits; LIHC cis rs2304069 0.545 rs9686746 chr5:149399968 G/A cg12661370 chr5:149340060 SLC26A2 0.51 7.48 0.37 6.32e-13 HIV-1 control; LIHC cis rs79839061 0.666 rs62297063 chr4:869708 G/A cg07828340 chr4:882639 GAK 0.83 7.04 0.36 1.05e-11 Intelligence (multi-trait analysis); LIHC cis rs986417 0.901 rs6573315 chr14:60996831 A/C cg27398547 chr14:60952738 C14orf39 0.75 8.1 0.4 9.98e-15 Gut microbiota (bacterial taxa); LIHC cis rs16828019 0.850 rs12027691 chr1:41462032 C/T cg03962019 chr1:41807865 NA 0.53 7.01 0.35 1.26e-11 Intelligence (multi-trait analysis); LIHC cis rs12220238 1.000 rs12256105 chr10:75909634 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.77 0.34 5.63e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs3815700 1.000 rs7248845 chr19:33096718 T/C cg02997394 chr19:33096574 ANKRD27 0.74 9.77 0.47 4.69e-20 Eosinophilic esophagitis; LIHC cis rs796364 1.000 rs4263095 chr2:200830137 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -7.86 -0.39 4.94e-14 Schizophrenia; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg07167872 chr1:205819463 PM20D1 0.59 8.61 0.42 2.79e-16 Menarche (age at onset); LIHC cis rs7208859 0.623 rs7503335 chr17:29073962 G/A cg14067834 chr17:29058358 SUZ12P 0.7 7.12 0.36 6.32e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11758351 1.000 rs17598927 chr6:26184640 C/G cg03785755 chr6:26196794 NA -0.52 -5.72 -0.3 2.38e-8 Gout;Renal underexcretion gout; LIHC cis rs3617 0.573 rs9810807 chr3:52924227 C/T cg11645453 chr3:52864694 ITIH4 -0.22 -5.79 -0.3 1.59e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC trans rs3780486 0.718 rs10971418 chr9:33122024 A/C cg04842962 chr6:43655489 MRPS18A -0.84 -12.53 -0.56 6.84e-30 IgG glycosylation; LIHC cis rs10791097 0.694 rs4457753 chr11:130755575 A/G cg12179176 chr11:130786555 SNX19 0.84 13.46 0.59 1.96e-33 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7772486 0.790 rs1062068 chr6:146207465 A/G cg23711669 chr6:146136114 FBXO30 0.71 12.41 0.56 1.96e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769707 0.967 rs763126 chr22:49988574 G/T cg07959070 chr22:50026188 C22orf34 0.3 7.77 0.39 9.07e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9303280 0.870 rs1011082 chr17:38068514 T/C cg11212589 chr17:38028394 ZPBP2 -0.36 -7.39 -0.37 1.11e-12 Self-reported allergy; LIHC cis rs7520050 0.966 rs11211199 chr1:46287869 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.01 0.31 4.62e-9 Red blood cell count;Reticulocyte count; LIHC cis rs362296 0.661 rs3095079 chr4:3265414 A/G cg06533319 chr4:3265114 C4orf44 -0.34 -6.53 -0.33 2.33e-10 Parental longevity (mother's age at death); LIHC trans rs8117834 0.511 rs1079778 chr20:8084107 A/T cg00593689 chr4:53575888 NA 0.38 6.5 0.33 2.77e-10 Chronic kidney disease; LIHC cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg19774624 chr17:42201019 HDAC5 -0.79 -12.15 -0.55 1.83e-28 Total body bone mineral density; LIHC trans rs7674212 0.570 rs2251634 chr4:104082349 C/T cg16471864 chr4:38666270 KLF3;FLJ13197 -0.45 -6.44 -0.33 4.11e-10 Type 2 diabetes; LIHC cis rs12079745 0.590 rs76722603 chr1:169321442 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.79 -7.08 -0.36 8.09e-12 QT interval; LIHC cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg09904177 chr6:26538194 HMGN4 -0.56 -11.22 -0.52 4.28e-25 Intelligence (multi-trait analysis); LIHC cis rs4642101 0.686 rs13085726 chr3:12832672 A/C cg24848339 chr3:12840334 CAND2 0.32 6.59 0.34 1.67e-10 QRS complex (12-leadsum); LIHC cis rs611744 0.810 rs672161 chr8:109164182 G/A cg21045802 chr8:109455806 TTC35 0.57 9.86 0.47 2.31e-20 Dupuytren's disease; LIHC cis rs2153535 0.580 rs4587214 chr6:8454119 T/C cg07606381 chr6:8435919 SLC35B3 0.8 12.07 0.55 3.38e-28 Motion sickness; LIHC cis rs2845885 0.793 rs57779243 chr11:63882363 G/T cg19006947 chr11:64034861 PLCB3 -0.46 -7.21 -0.36 3.51e-12 Body mass index; LIHC cis rs2455799 0.502 rs2470532 chr3:15696909 A/C cg12698662 chr3:15914712 MIR563 0.36 6.81 0.35 4.5e-11 Mean platelet volume; LIHC cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg11644478 chr21:40555479 PSMG1 0.72 9.21 0.45 3.25e-18 Cognitive function; LIHC trans rs208520 0.507 rs9453585 chr6:66796668 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.02 -20.18 -0.74 3.41e-60 Exhaled nitric oxide output; LIHC cis rs611744 0.870 rs633794 chr8:109174702 A/G cg18478394 chr8:109455254 TTC35 0.4 6.8 0.35 4.75e-11 Dupuytren's disease; LIHC cis rs4665809 1.000 rs6739061 chr2:26256147 C/T cg04944784 chr2:26401820 FAM59B -0.67 -8.47 -0.42 7.15e-16 Gut microbiome composition (summer); LIHC cis rs7208859 0.623 rs7503542 chr17:29073830 A/C cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 0.660 rs6460308 chr7:66084740 T/C cg00343986 chr7:65444356 GUSB -0.39 -5.81 -0.3 1.45e-8 Aortic root size; LIHC cis rs9326778 0.520 rs4635977 chr5:108840166 A/T cg17395555 chr5:108820864 NA 0.35 5.91 0.3 8.2e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC trans rs875971 1.000 rs778694 chr7:65871558 A/G cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg07424592 chr7:64974309 NA 0.79 9.07 0.44 9.53e-18 Diabetic kidney disease; LIHC cis rs10056811 0.538 rs4632781 chr5:74376658 G/C cg19683494 chr5:74908142 NA 0.7 7.73 0.39 1.21e-13 Coronary artery disease; LIHC cis rs2762353 0.505 rs2096386 chr6:25787817 C/T cg12310025 chr6:25882481 NA 0.41 6.13 0.31 2.44e-9 Blood metabolite levels; LIHC cis rs8064024 0.650 rs3813749 chr16:4919127 T/C cg08329684 chr16:4932620 PPL 0.35 5.97 0.31 6.02e-9 Cancer; LIHC cis rs922107 0.738 rs12739453 chr1:90040287 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.6 -0.38 2.8e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12145289 chr11:65385911 PCNXL3 -0.39 -6.27 -0.32 1.07e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4713118 0.515 rs9368549 chr6:28050047 T/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Parkinson's disease; LIHC cis rs7726839 0.555 rs4541696 chr5:581053 A/G cg23206463 chr5:561769 NA -0.5 -8.16 -0.4 6.51e-15 Obesity-related traits; LIHC cis rs7208859 0.623 rs9891166 chr17:29111902 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg08219700 chr8:58056026 NA 0.44 5.74 0.3 2.09e-8 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.52 0.38 4.82e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3806843 0.735 rs3776129 chr5:140072292 G/A cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs858239 0.601 rs28673077 chr7:23250854 C/T cg18081818 chr7:23246105 NA -0.42 -6.01 -0.31 4.74e-9 Cerebrospinal fluid biomarker levels; LIHC trans rs11039798 0.841 rs7950737 chr11:48590678 T/G cg15704280 chr7:45808275 SEPT13 0.6 6.12 0.31 2.53e-9 Axial length; LIHC cis rs7772486 0.790 rs2249147 chr6:146184999 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.58 0.53 2.13e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7131987 0.834 rs11050167 chr12:29426387 C/T cg12903224 chr12:29470962 FAR2 -0.39 -5.99 -0.31 5.39e-9 QT interval; LIHC cis rs2236918 1.000 rs2526699 chr1:242022130 T/C cg17736920 chr1:242011382 EXO1 0.59 8.65 0.42 2.05e-16 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05136179 chr3:52740483 GLT8D1;SPCS1 0.47 6.21 0.32 1.58e-9 Lung function (FEV1/FVC); LIHC cis rs3806843 1.000 rs1548701 chr5:140164557 T/C cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs4819052 0.851 rs3673 chr21:46681775 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.83 0.39 6.13e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7927771 0.864 rs10838724 chr11:47527052 G/T cg20135002 chr11:47629003 NA -0.56 -9.77 -0.47 4.76e-20 Subjective well-being; LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg18306943 chr3:40428807 ENTPD3 0.42 7.48 0.37 6.3e-13 Renal cell carcinoma; LIHC cis rs7264396 0.635 rs6058346 chr20:34481043 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.56 -8.18 -0.4 5.53e-15 Total cholesterol levels; LIHC cis rs1691799 0.899 rs1168315 chr12:66746694 A/G cg16791601 chr12:66731901 HELB -0.56 -13.94 -0.6 2.85e-35 White blood cell count (basophil); LIHC cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs12908161 0.959 rs34028043 chr15:85231585 G/A cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC cis rs7412746 0.611 rs7556661 chr1:150892009 C/T cg15448220 chr1:150897856 SETDB1 0.44 7.08 0.36 8.3e-12 Melanoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10354764 chr16:3285464 ZNF200 0.4 6.47 0.33 3.31e-10 Cognitive function; LIHC cis rs734999 0.588 rs10910098 chr1:2533250 C/A cg18854424 chr1:2615690 NA 0.32 7.07 0.36 8.7e-12 Ulcerative colitis; LIHC cis rs2522056 0.808 rs17771891 chr5:131744202 A/G cg24060327 chr5:131705240 SLC22A5 -0.59 -7.72 -0.39 1.28e-13 Lymphocyte counts;Fibrinogen; LIHC cis rs8067545 0.750 rs9897653 chr17:19987924 G/A cg13482628 chr17:19912719 NA 0.49 8.22 0.41 4.28e-15 Schizophrenia; LIHC cis rs875971 0.964 rs1643388 chr7:65844562 T/C cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs965469 1.000 rs6037533 chr20:3268817 T/C cg25506879 chr20:3388711 C20orf194 -0.58 -7.06 -0.36 9.15e-12 IFN-related cytopenia; LIHC cis rs35306767 0.903 rs12249828 chr10:894838 C/T cg26597838 chr10:835615 NA 1.16 14.03 0.6 1.18e-35 Eosinophil percentage of granulocytes; LIHC cis rs6951245 0.872 rs75280240 chr7:1058511 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.75 -6.22 -0.32 1.42e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1190552 0.846 rs3783382 chr14:102965437 A/T cg10241871 chr14:102965420 TECPR2 -0.48 -7.53 -0.38 4.65e-13 Blood protein levels; LIHC cis rs644799 0.526 rs506180 chr11:95623109 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.61 9.57 0.46 2.18e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg05560165 chr5:133450315 TCF7 0.36 6.5 0.33 2.78e-10 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC cis rs911555 0.723 rs56227024 chr14:103861706 A/G cg24130564 chr14:104152367 KLC1 0.36 5.72 0.3 2.35e-8 Intelligence (multi-trait analysis); LIHC cis rs174551 1 rs174551 chr11:61573684 T/C cg07689907 chr11:61582574 FADS1 0.39 5.77 0.3 1.77e-8 LDL cholesterol; LIHC cis rs4930103 0.619 rs10769945 chr11:1985127 C/T cg23202291 chr11:1979235 NA 0.5 7.5 0.38 5.48e-13 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs798554 0.660 rs1182175 chr7:2875026 C/T cg19717773 chr7:2847554 GNA12 0.39 6.9 0.35 2.54e-11 Height; LIHC cis rs1144333 0.655 rs17097681 chr1:76376926 C/T cg10523679 chr1:76189770 ACADM 0.44 5.88 0.3 9.62e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs2073300 1.000 rs114718317 chr20:23442620 T/C cg12062639 chr20:23401060 NAPB 0.84 9.86 0.47 2.44e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs798502 0.541 rs2644307 chr7:2832973 G/A cg18446336 chr7:2847575 GNA12 -0.35 -6.79 -0.34 4.91e-11 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Inflammatory bowel disease;Waist circumference adjusted for BMI in non-smokers;Ulcerative colitis;Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg12379764 chr21:47803548 PCNT 0.54 8.0 0.4 1.96e-14 Testicular germ cell tumor; LIHC cis rs3204270 0.759 rs8066217 chr17:79672615 C/G cg18367735 chr17:79674897 NA 0.73 8.53 0.42 4.78e-16 Dental caries; LIHC cis rs13108904 0.901 rs1316393 chr4:1315619 A/G cg00684032 chr4:1343700 KIAA1530 -0.53 -7.7 -0.38 1.51e-13 Obesity-related traits; LIHC cis rs9910055 0.593 rs58392387 chr17:42297889 A/G cg13607699 chr17:42295918 UBTF 0.77 15.73 0.65 2.48e-42 Total body bone mineral density; LIHC cis rs9921222 0.542 rs9926968 chr16:381561 A/C cg08923669 chr16:420230 MRPL28 -0.43 -5.73 -0.3 2.17e-8 Bone mineral density (spine);Bone mineral density; LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs2576037 0.526 rs998819 chr18:44564181 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.48 7.0 0.35 1.34e-11 Personality dimensions; LIHC cis rs6964587 1.000 rs2282970 chr7:91584281 A/G cg17063962 chr7:91808500 NA 1.03 20.57 0.74 8.9e-62 Breast cancer; LIHC cis rs2243480 1.000 rs73142122 chr7:65311298 C/A cg18252515 chr7:66147081 NA -1.3 -16.6 -0.67 8.39e-46 Diabetic kidney disease; LIHC cis rs4919694 0.611 rs7091462 chr10:104948615 C/T cg04362960 chr10:104952993 NT5C2 0.82 7.11 0.36 6.78e-12 Arsenic metabolism; LIHC cis rs1552244 0.554 rs6443275 chr3:10008819 G/A cg21531657 chr3:10005747 TMEM111 0.39 5.76 0.3 1.86e-8 Alzheimer's disease; LIHC cis rs17685 0.735 rs11763339 chr7:75761541 T/C cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1552244 0.816 rs17050701 chr3:10041554 A/G cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs8180040 0.966 rs4858868 chr3:47455086 G/A cg27129171 chr3:47204927 SETD2 0.57 9.72 0.47 7.13e-20 Colorectal cancer; LIHC cis rs8020095 0.528 rs28521373 chr14:67738075 T/C cg03487553 chr14:67822707 ATP6V1D -0.33 -5.71 -0.3 2.42e-8 Depression (quantitative trait); LIHC cis rs7927592 0.645 rs7936582 chr11:68292930 T/C cg16797656 chr11:68205561 LRP5 0.47 7.93 0.39 3.17e-14 Total body bone mineral density; LIHC cis rs6430585 0.528 rs3112496 chr2:136711064 C/T cg07169764 chr2:136633963 MCM6 0.97 14.97 0.63 2.64e-39 Corneal structure; LIHC cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg21644426 chr2:191273491 MFSD6 0.54 7.59 0.38 3.09e-13 Pulse pressure; LIHC cis rs4319547 0.656 rs10773075 chr12:122814236 G/A cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.16 -0.36 4.99e-12 Body mass index; LIHC cis rs9646954 0.542 rs4149513 chr2:101022726 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.46 0.42 8.18e-16 Intelligence (multi-trait analysis); LIHC cis rs509477 1.000 rs531558 chr18:32575286 A/T cg23791764 chr18:32556832 MAPRE2 -0.51 -7.38 -0.37 1.21e-12 Cerebrospinal fluid AB1-42 levels; LIHC trans rs4843747 0.671 rs9933794 chr16:88116981 T/C cg09572067 chr16:29127029 RRN3P2 0.53 8.07 0.4 1.23e-14 Menopause (age at onset); LIHC cis rs4843747 0.605 rs4072779 chr16:88107290 C/T cg00677901 chr16:88017247 BANP 0.51 7.77 0.39 9.22e-14 Menopause (age at onset); LIHC cis rs6918586 0.636 rs198817 chr6:26126524 A/G cg18357526 chr6:26021779 HIST1H4A -0.57 -8.65 -0.42 2.02e-16 Schizophrenia; LIHC cis rs5770917 1.000 rs1557503 chr22:51013072 G/A cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.51 -6.78 -0.34 5.16e-11 Narcolepsy; LIHC cis rs875971 0.660 rs12698534 chr7:65986845 C/T cg18876405 chr7:65276391 NA 0.44 7.78 0.39 8.74e-14 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18342900 chr16:46865048 C16orf87 0.46 6.59 0.34 1.66e-10 Pancreatic cancer; LIHC cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.55 0.56 5.46e-30 Alzheimer's disease; LIHC cis rs6942756 0.713 rs691158 chr7:129129982 G/T cg02491457 chr7:128862824 NA -0.55 -8.5 -0.42 5.84e-16 White matter hyperintensity burden; LIHC cis rs77861329 1.000 rs9815010 chr3:52196548 C/T cg08692210 chr3:52188851 WDR51A 0.81 7.64 0.38 2.2e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs1443512 0.812 rs1975470 chr12:54336841 G/A cg17410650 chr12:54324560 NA -0.37 -6.7 -0.34 8.75e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13557139 chr1:156630023 NA 0.44 6.13 0.31 2.39e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs986417 0.901 rs10151423 chr14:60996667 A/G cg27398547 chr14:60952738 C14orf39 0.81 9.34 0.45 1.25e-18 Gut microbiota (bacterial taxa); LIHC cis rs11112613 0.713 rs2374502 chr12:105938939 T/C cg03607813 chr12:105948248 NA 0.65 12.74 0.57 1.0500000000000001e-30 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs1153858 1.000 rs4775911 chr15:45649787 G/T cg21132104 chr15:45694354 SPATA5L1 -0.45 -7.32 -0.37 1.8e-12 Homoarginine levels; LIHC cis rs7927771 0.832 rs896816 chr11:47394338 T/C cg20135002 chr11:47629003 NA 0.5 8.4 0.41 1.17e-15 Subjective well-being; LIHC cis rs1144333 1.000 rs5745343 chr1:76273805 A/G cg10523679 chr1:76189770 ACADM -0.44 -6.56 -0.33 2.02e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs727505 1.000 rs34986416 chr7:124441017 A/G cg23710748 chr7:124431027 NA -0.35 -6.19 -0.32 1.68e-9 Lewy body disease; LIHC cis rs7520050 0.933 rs6656022 chr1:46394315 A/G cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7615952 0.599 rs6779141 chr3:125709995 A/T cg05084668 chr3:125655381 ALG1L -0.43 -6.98 -0.35 1.58e-11 Blood pressure (smoking interaction); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg22671938 chr6:21596462 SOX4 -0.44 -6.15 -0.32 2.21e-9 Migraine with aura; LIHC cis rs2836950 0.565 rs2836943 chr21:40592611 C/T cg11890956 chr21:40555474 PSMG1 -0.47 -7.59 -0.38 3.15e-13 Menarche (age at onset); LIHC cis rs11583043 0.793 rs3903905 chr1:101420957 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.2 0.41 4.77e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs597539 0.690 rs647661 chr11:68625875 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.72 10.01 0.48 7.45e-21 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs11690935 0.589 rs62182403 chr2:172747182 G/A cg13550731 chr2:172543902 DYNC1I2 0.41 6.07 0.31 3.42e-9 Schizophrenia; LIHC cis rs12220238 0.915 rs7922519 chr10:75976573 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.46 0.33 3.6e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg13409248 chr3:40428643 ENTPD3 0.5 8.35 0.41 1.66e-15 Renal cell carcinoma; LIHC cis rs13191362 0.935 rs73008456 chr6:163013697 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.63 5.92 0.3 7.72e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1018836 0.828 rs1858673 chr8:91551526 C/A cg16814680 chr8:91681699 NA -0.57 -9.11 -0.44 7.26e-18 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08957018 chr22:42487540 NDUFA6 0.39 6.17 0.32 1.93e-9 Cognitive function; LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg07677032 chr17:61819896 STRADA 0.44 6.35 0.32 6.82e-10 Prudent dietary pattern; LIHC cis rs910316 0.712 rs175015 chr14:75457075 A/C cg08847533 chr14:75593920 NEK9 -0.86 -17.2 -0.68 3.23e-48 Height; LIHC cis rs5769765 0.908 rs7410601 chr22:50317187 C/T cg26441486 chr22:50317300 CRELD2 0.4 6.76 0.34 5.91e-11 Schizophrenia; LIHC cis rs919433 1.000 rs6761919 chr2:198163328 A/G cg10820045 chr2:198174542 NA -0.61 -10.36 -0.49 4.73e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs963731 0.649 rs77498284 chr2:39349726 C/A cg04010122 chr2:39346883 SOS1 0.69 6.08 0.31 3.14e-9 Corticobasal degeneration; LIHC cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9790314 0.521 rs1450523 chr3:161077270 G/A cg17135325 chr3:160939158 NMD3 0.42 5.95 0.31 6.55e-9 Morning vs. evening chronotype; LIHC cis rs2991971 0.810 rs6657237 chr1:45920108 A/T cg15605315 chr1:45957053 TESK2 -0.49 -6.98 -0.35 1.55e-11 High light scatter reticulocyte count; LIHC cis rs4474465 0.688 rs4275650 chr11:78284822 T/A cg27205649 chr11:78285834 NARS2 0.5 7.83 0.39 6.34e-14 Alzheimer's disease (survival time); LIHC cis rs7520050 0.751 rs2230657 chr1:46073489 G/A cg24296786 chr1:45957014 TESK2 0.44 6.26 0.32 1.15e-9 Red blood cell count;Reticulocyte count; LIHC cis rs60871478 1.000 rs12531530 chr7:827366 T/C cg27478167 chr7:817139 HEATR2 -0.53 -7.09 -0.36 7.51e-12 Cerebrospinal P-tau181p levels; LIHC trans rs2270927 0.510 rs7730153 chr5:75579762 A/G cg13563193 chr19:33072644 PDCD5 -0.98 -10.28 -0.49 8.63e-22 Mean corpuscular volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22152050 chr18:60987904 BCL2 0.45 6.18 0.32 1.83e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg18538332 chr22:24372958 LOC391322 -0.65 -9.86 -0.47 2.38e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11122272 0.735 rs2572252 chr1:231513653 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs6504950 0.566 rs7208403 chr17:53046667 C/A cg19360675 chr17:53046073 COX11;STXBP4 0.6 8.87 0.43 4.17e-17 Breast cancer; LIHC cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg12042659 chr19:58951599 ZNF132 0.37 6.04 0.31 4.06e-9 Uric acid clearance; LIHC cis rs1568889 1.000 rs7937117 chr11:28370038 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.75 0.34 6.52e-11 Bipolar disorder; LIHC cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg13047869 chr3:10149882 C3orf24 0.49 6.43 0.33 4.26e-10 Alzheimer's disease; LIHC cis rs7582180 0.629 rs4851297 chr2:100949571 G/A cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.97e-16 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9814567 1.000 rs9832785 chr3:134213070 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.09 -0.55 2.9e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs28830936 0.966 rs3743024 chr15:42118971 A/G cg17847044 chr15:42102381 MAPKBP1 -0.31 -5.97 -0.31 5.9e-9 Diastolic blood pressure; LIHC cis rs7312933 1.000 rs3229 chr12:42475888 G/A cg17420585 chr12:42539391 GXYLT1 -0.37 -5.89 -0.3 9.43e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.9 -0.35 2.6e-11 Gut microbiome composition (summer); LIHC cis rs7903847 0.642 rs7092350 chr10:99140218 A/T cg08345082 chr10:99160200 RRP12 -0.4 -6.8 -0.35 4.57e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs2997447 0.846 rs3008414 chr1:26404747 G/A cg19633962 chr1:26362018 EXTL1 -0.62 -5.72 -0.3 2.29e-8 QRS complex (12-leadsum); LIHC cis rs7508679 1.000 rs4804411 chr19:7222377 G/C cg09779027 chr19:7224513 INSR 0.29 6.64 0.34 1.23e-10 Hypothyroidism; LIHC cis rs798554 0.836 rs13243214 chr7:2817455 G/T cg13628971 chr7:2884303 GNA12 0.53 7.7 0.38 1.51e-13 Height; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg23144123 chr6:147828073 NA 0.37 6.16 0.32 2.04e-9 Migraine with aura; LIHC cis rs34779708 0.966 rs1478463 chr10:35473035 G/A cg03585969 chr10:35415529 CREM 0.86 13.05 0.58 7.33e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17401966 0.838 rs34636442 chr1:10427459 T/G cg19773385 chr1:10388646 KIF1B -0.39 -6.97 -0.35 1.63e-11 Hepatocellular carcinoma; LIHC cis rs67311347 1.000 rs4246666 chr3:40407670 C/T cg00656387 chr3:40428638 ENTPD3 0.41 6.87 0.35 2.97e-11 Renal cell carcinoma; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg05025164 chr4:1340916 KIAA1530 0.81 12.92 0.57 2.26e-31 Longevity; LIHC cis rs17270561 0.583 rs7765833 chr6:25712433 C/A cg17691542 chr6:26056736 HIST1H1C 0.46 6.14 0.31 2.33e-9 Iron status biomarkers; LIHC cis rs34779708 0.931 rs11597483 chr10:35285117 A/G cg03585969 chr10:35415529 CREM 0.87 13.04 0.58 7.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11718455 0.960 rs11920021 chr3:44000856 T/C cg08738300 chr3:44038990 NA 0.51 8.82 0.43 6.01e-17 Coronary artery disease; LIHC cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg23758822 chr17:41437982 NA 0.94 17.56 0.69 1.21e-49 Menopause (age at onset); LIHC cis rs1434579 0.652 rs2356889 chr19:44936245 A/G cg15540054 chr19:45004280 ZNF180 0.65 9.83 0.47 3.04e-20 Tuberculosis; LIHC cis rs7098414 0.511 rs7899513 chr10:82150559 G/A cg01528321 chr10:82214614 TSPAN14 0.42 6.35 0.32 6.89e-10 Post bronchodilator FEV1; LIHC cis rs7246657 0.943 rs10420722 chr19:37973774 C/G cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.62e-10 Coronary artery calcification; LIHC cis rs6570726 0.875 rs416243 chr6:145868081 A/T cg23711669 chr6:146136114 FBXO30 0.56 10.02 0.48 7.09e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 0.755 rs12447461 chr16:28582941 C/A cg07382826 chr16:28625726 SULT1A1 0.49 7.65 0.38 2.01e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7572733 0.534 rs700674 chr2:198693703 C/T cg10820045 chr2:198174542 NA 0.46 6.9 0.35 2.59e-11 Dermatomyositis; LIHC cis rs11233413 1.000 rs4944422 chr11:82715482 T/C cg24227371 chr11:82718527 RAB30 -0.33 -7.17 -0.36 4.74e-12 Economic and political preferences (feminism/equality); LIHC cis rs74417235 0.684 rs13185173 chr5:154055081 A/G cg08754654 chr5:154026448 NA 0.32 7.05 0.36 1.01e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs9921222 1.000 rs10794639 chr16:377367 A/G cg26913058 chr16:419975 MRPL28 -0.42 -5.83 -0.3 1.27e-8 Bone mineral density (spine);Bone mineral density; LIHC cis rs769267 0.965 rs1010207 chr19:19416045 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.07 0.31 3.47e-9 Tonsillectomy; LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg24209194 chr3:40518798 ZNF619 0.56 8.15 0.4 6.98e-15 Renal cell carcinoma; LIHC cis rs2439831 1.000 rs2251538 chr15:43767209 G/C cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.32e-9 Lung cancer in ever smokers; LIHC cis rs896854 0.517 rs1011795 chr8:95951073 G/A cg09323728 chr8:95962352 TP53INP1 -0.28 -5.75 -0.3 2e-8 Type 2 diabetes; LIHC cis rs589448 0.538 rs683790 chr12:69751434 T/G cg19645103 chr12:69753606 YEATS4 -0.51 -7.58 -0.38 3.27e-13 Cerebrospinal fluid biomarker levels; LIHC cis rs743757 1.000 rs2236955 chr3:50429876 G/A cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.14 0.32 2.25e-9 Diastolic blood pressure; LIHC cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.09 -0.36 7.87e-12 Bipolar disorder; LIHC cis rs116095464 0.681 rs10060016 chr5:241100 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.71 -0.5 2.89e-23 Breast cancer; LIHC cis rs13336428 0.730 rs28653458 chr16:1525850 T/C cg08008072 chr16:1524255 CLCN7 -0.62 -11.84 -0.54 2.46e-27 Bone mineral density; LIHC cis rs74233809 1.000 rs11191543 chr10:104824387 G/A cg03493300 chr10:104813866 CNNM2 0.48 6.36 0.33 6.41e-10 Birth weight; LIHC cis rs3106136 0.872 rs2059606 chr4:95255278 C/T cg11021082 chr4:95130006 SMARCAD1 0.38 6.77 0.34 5.52e-11 Capecitabine sensitivity; LIHC cis rs4728302 0.838 rs6954700 chr7:133588739 G/A cg10665199 chr7:133106180 EXOC4 0.36 6.31 0.32 8.4e-10 Intelligence;Intelligence (multi-trait analysis); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg09021898 chr2:174075476 ZAK 0.31 6.44 0.33 3.96e-10 Calcium levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16451430 chr20:42940032 FITM2 0.44 6.14 0.32 2.35e-9 Lung function (FEV1/FVC); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21452443 chr17:43138359 NMT1;DCAKD -0.5 -6.23 -0.32 1.4e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg02290350 chr8:58132656 NA 0.49 10.48 0.49 1.81e-22 Developmental language disorder (linguistic errors); LIHC cis rs9640161 0.789 rs1464752 chr7:150021284 C/T cg17279839 chr7:150038598 RARRES2 0.51 10.71 0.5 2.84e-23 Blood protein levels;Circulating chemerin levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23182539 chr10:121355708 TIAL1 0.39 6.33 0.32 7.91e-10 Cognitive function; LIHC cis rs17854409 0.764 rs16983293 chr20:61479056 A/G cg06598544 chr20:61472147 COL9A3 -0.88 -7.83 -0.39 6.11e-14 Obesity-related traits; LIHC cis rs4819052 0.807 rs7283915 chr21:46671288 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.88 0.39 4.27e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs367615 0.552 rs2963010 chr5:108737043 T/C cg17395555 chr5:108820864 NA -0.28 -6.06 -0.31 3.57e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs17685 0.753 rs2302438 chr7:75677065 C/A cg16684958 chr7:75615977 POR 0.5 8.39 0.41 1.27e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9513627 0.573 rs12431100 chr13:100184918 C/G cg15490075 chr13:100150979 NA -0.79 -11.16 -0.52 7.03e-25 Obesity-related traits; LIHC cis rs1062177 0.756 rs2964588 chr5:151118386 C/T cg00977110 chr5:151150581 G3BP1 -0.57 -7.12 -0.36 6.25e-12 Preschool internalizing problems; LIHC cis rs11532322 1 rs11532322 chr12:123731423 A/G cg05973401 chr12:123451056 ABCB9 0.43 5.94 0.31 7.13e-9 Schizophrenia; LIHC cis rs11792861 0.781 rs11793272 chr9:111762102 G/A cg05043794 chr9:111880884 C9orf5 -0.32 -7.21 -0.36 3.56e-12 Menarche (age at onset); LIHC cis rs637571 0.676 rs1151523 chr11:65665200 C/T cg26695010 chr11:65641043 EFEMP2 0.43 5.98 0.31 5.66e-9 Eosinophil percentage of white cells; LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg24503407 chr1:205819492 PM20D1 0.73 10.24 0.48 1.21e-21 Menarche (age at onset); LIHC trans rs11098499 0.954 rs35063680 chr4:120387102 T/C cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg07424592 chr7:64974309 NA -0.44 -6.63 -0.34 1.28e-10 Calcium levels; LIHC cis rs919433 1.000 rs1429414 chr2:198162430 C/T cg10820045 chr2:198174542 NA -0.58 -9.85 -0.47 2.55e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9649465 0.561 rs631445 chr7:123413707 C/T cg03229431 chr7:123269106 ASB15 -0.4 -8.55 -0.42 4.13e-16 Migraine; LIHC cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg10802521 chr3:52805072 NEK4 -0.43 -7.16 -0.36 5.06e-12 Bipolar disorder; LIHC cis rs344364 0.511 rs337284 chr16:1954799 A/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.51 -6.5 -0.33 2.77e-10 Glomerular filtration rate in chronic kidney disease; LIHC cis rs61041384 0.661 rs4148858 chr12:123540022 G/A cg25930673 chr12:123319894 HIP1R 0.64 5.83 0.3 1.31e-8 Schizophrenia; LIHC cis rs2033711 0.870 rs7409473 chr19:58939165 A/G cg03735888 chr19:58951602 ZNF132 0.36 5.95 0.31 6.5e-9 Uric acid clearance; LIHC cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg17644776 chr2:200775616 C2orf69 0.42 6.0 0.31 5.15e-9 Osteoporosis; LIHC cis rs2637266 0.935 rs4520537 chr10:78392978 C/T cg18941641 chr10:78392320 NA 0.29 6.44 0.33 4.17e-10 Pulmonary function; LIHC cis rs1577917 0.876 rs1582127 chr6:86697204 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.52 -0.46 3.19e-19 Response to antipsychotic treatment; LIHC cis rs2361718 1.000 rs2361718 chr17:78103466 C/T cg09238746 chr17:78121135 EIF4A3 -0.48 -7.21 -0.36 3.56e-12 Yeast infection; LIHC cis rs8141529 0.748 rs9620841 chr22:29290981 C/T cg15103426 chr22:29168792 CCDC117 0.58 9.41 0.45 7.54e-19 Lymphocyte counts; LIHC cis rs8053891 0.906 rs12149877 chr16:71996067 T/C cg01557791 chr16:72042693 DHODH -0.42 -6.17 -0.32 1.91e-9 Coronary artery disease; LIHC cis rs1912483 0.505 rs11079772 chr17:45393739 A/C cg25173405 chr17:45401733 C17orf57 0.53 7.13 0.36 5.83e-12 Coronary artery disease; LIHC cis rs1712517 0.904 rs6584547 chr10:105065409 C/T cg05636881 chr10:105038444 INA 0.45 6.96 0.35 1.72e-11 Migraine; LIHC cis rs9596863 0.898 rs8000371 chr13:54344502 A/G ch.13.53330881F chr13:54432880 NA 0.44 5.88 0.3 9.89e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs7937682 0.961 rs11601674 chr11:111634354 C/T cg09085632 chr11:111637200 PPP2R1B -1.21 -19.58 -0.73 8.44e-58 Primary sclerosing cholangitis; LIHC cis rs2073300 0.609 rs6137917 chr20:23360369 G/A cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4684776 0.867 rs13081232 chr3:11342271 T/G cg00170343 chr3:11313890 ATG7 -0.53 -7.28 -0.37 2.31e-12 Small vessel stroke; LIHC cis rs34172651 0.874 rs200534 chr16:24752641 G/A cg04756594 chr16:24857601 SLC5A11 -0.47 -7.36 -0.37 1.37e-12 Intelligence (multi-trait analysis); LIHC cis rs7582720 1.000 rs115810193 chr2:203943168 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg03806693 chr22:41940476 POLR3H -1.04 -11.94 -0.54 1.04e-27 Vitiligo; LIHC cis rs1008375 0.931 rs7672369 chr4:17604825 A/G cg16339924 chr4:17578868 LAP3 0.41 5.78 0.3 1.65e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7772486 0.790 rs1062068 chr6:146207465 A/G cg05347473 chr6:146136440 FBXO30 0.39 6.15 0.32 2.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11583043 0.918 rs6675403 chr1:101418569 T/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.81 0.3 1.43e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4144743 0.759 rs16941731 chr17:45317022 C/T cg18085866 chr17:45331354 ITGB3 0.63 7.33 0.37 1.62e-12 Body mass index; LIHC cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg18357526 chr6:26021779 HIST1H4A 1.05 15.6 0.64 8.26e-42 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.837 rs2838336 chr21:45071741 A/G cg21573476 chr21:45109991 RRP1B 0.5 9.65 0.46 1.19e-19 Mean corpuscular volume; LIHC cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.52 -8.99 -0.44 1.71e-17 Bipolar disorder; LIHC cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs208520 1.000 rs12190773 chr6:66968194 T/C cg07460842 chr6:66804631 NA 0.65 7.0 0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs67614146 1 rs67614146 chr6:87821827 AC/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.61 -11.46 -0.53 5.77e-26 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2976388 1.000 rs2920292 chr8:143765699 A/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.21e-9 Urinary tract infection frequency; LIHC cis rs11864453 1.000 rs7201491 chr16:72034312 G/A cg16558253 chr16:72132732 DHX38 -0.42 -5.74 -0.3 2.06e-8 Fibrinogen levels; LIHC cis rs9814567 0.752 rs6779294 chr3:134329821 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg22903471 chr2:27725779 GCKR -0.46 -7.85 -0.39 5.35e-14 Menopause (age at onset); LIHC cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg06238570 chr21:40685208 BRWD1 0.57 6.91 0.35 2.37e-11 Cognitive function; LIHC cis rs79387448 0.745 rs79107058 chr2:103164257 C/A cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs10504229 0.593 rs1442127 chr8:57992136 T/C cg20607798 chr8:58055168 NA 0.45 5.98 0.31 5.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.656 rs4997380 chr12:122838956 A/G cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.36 -0.37 1.37e-12 Body mass index; LIHC cis rs10242455 0.557 rs73401516 chr7:99068351 C/A cg18809830 chr7:99032528 PTCD1 -0.82 -6.38 -0.33 5.89e-10 Blood metabolite levels; LIHC cis rs748404 0.697 rs531910 chr15:43560607 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 6.85 0.35 3.49e-11 Lung cancer; LIHC cis rs918629 0.761 rs3777173 chr5:95281353 C/T cg10483112 chr5:95245456 ELL2 -0.38 -6.37 -0.33 6.26e-10 IgG glycosylation; LIHC trans rs2727020 0.521 rs937430 chr11:49542457 A/G cg18944383 chr4:111397179 ENPEP -0.34 -7.97 -0.4 2.41e-14 Coronary artery disease; LIHC trans rs6539288 0.803 rs10778517 chr12:107341664 G/T cg00860370 chr1:104068121 RNPC3 0.42 6.41 0.33 4.92e-10 Total body bone mineral density; LIHC cis rs72627509 0.904 rs56281640 chr4:57765816 G/A cg16868167 chr4:57843880 C4orf14;POLR2B -0.51 -7.24 -0.36 2.93e-12 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs2274273 1.000 rs10140857 chr14:55619611 G/C cg01864836 chr14:55583639 NA -0.35 -5.82 -0.3 1.36e-8 Protein biomarker; LIHC cis rs11105298 0.891 rs4842664 chr12:89938030 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.36 -0.37 1.39e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs60871478 0.578 rs62432900 chr7:826794 G/C cg00934597 chr7:893267 UNC84A 0.48 5.79 0.3 1.57e-8 Cerebrospinal P-tau181p levels; LIHC cis rs9952991 0.941 rs34920518 chr18:12783086 A/G cg23598886 chr18:12777645 NA -0.45 -6.04 -0.31 4.02e-9 Inflammatory skin disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06656027 chr12:50016493 PRPF40B 0.44 6.26 0.32 1.16e-9 Pancreatic cancer; LIHC cis rs7131987 0.903 rs11050152 chr12:29404424 G/T cg14222432 chr12:29376421 FAR2 0.37 7.04 0.36 1.05e-11 QT interval; LIHC cis rs611744 0.934 rs672591 chr8:109192453 T/A cg21045802 chr8:109455806 TTC35 0.51 8.68 0.42 1.63e-16 Dupuytren's disease; LIHC cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg21294424 chr19:58662284 ZNF329 0.91 6.98 0.35 1.52e-11 Cholesterol, total; LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.656 rs7397299 chr12:122821649 G/T cg23029597 chr12:123009494 RSRC2 -0.5 -7.27 -0.37 2.45e-12 Body mass index; LIHC cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg24675658 chr1:53192096 ZYG11B 0.67 10.69 0.5 3.22e-23 Monocyte count; LIHC cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg08499158 chr17:42289980 UBTF -0.49 -7.99 -0.4 2.15e-14 Total body bone mineral density; LIHC cis rs9790314 1.000 rs2218803 chr3:161047973 T/G cg03342759 chr3:160939853 NMD3 -0.7 -8.45 -0.42 8.24e-16 Morning vs. evening chronotype; LIHC cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.15e-51 Menopause (age at onset); LIHC cis rs523522 0.962 rs7136951 chr12:120941927 C/T cg12219531 chr12:120966889 COQ5 0.66 13.04 0.58 7.61e-32 High light scatter reticulocyte count; LIHC cis rs12744310 1.000 rs12032215 chr1:41769334 A/G cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs853679 0.517 rs4713145 chr6:28106827 T/C cg16479474 chr6:28041457 NA 0.46 6.52 0.33 2.53e-10 Depression; LIHC cis rs4803468 1.000 rs284651 chr19:41928336 T/C cg14132834 chr19:41945861 ATP5SL -0.46 -6.78 -0.34 5.21e-11 Height; LIHC cis rs597539 0.690 rs552517 chr11:68625286 T/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.71 9.91 0.47 1.58e-20 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6456156 0.792 rs4710178 chr6:167513532 G/A cg07741184 chr6:167504864 NA 0.28 6.89 0.35 2.69e-11 Primary biliary cholangitis; LIHC cis rs1878931 0.597 rs37814 chr16:3455247 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.68 -8.45 -0.42 8.33e-16 Body mass index (adult); LIHC cis rs7100689 0.622 rs7090351 chr10:82142047 T/G cg01528321 chr10:82214614 TSPAN14 0.85 12.2 0.55 1.11e-28 Post bronchodilator FEV1; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg23374814 chr5:72292757 FCHO2 0.61 6.33 0.32 7.77e-10 Mean platelet volume; LIHC cis rs6121246 0.567 rs6087701 chr20:30217708 A/C cg13852791 chr20:30311386 BCL2L1 0.78 6.77 0.34 5.69e-11 Mean corpuscular hemoglobin; LIHC cis rs9916302 0.768 rs11078900 chr17:37614641 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.34 -0.59 5.58e-33 Glomerular filtration rate (creatinine); LIHC cis rs2120019 0.567 rs72625793 chr15:75207083 A/G cg09165964 chr15:75287851 SCAMP5 -0.49 -6.51 -0.33 2.72e-10 Blood trace element (Zn levels); LIHC cis rs3815700 1.000 rs8109885 chr19:33095557 A/G cg02997394 chr19:33096574 ANKRD27 0.73 9.38 0.45 9.36e-19 Eosinophilic esophagitis; LIHC cis rs9611565 0.592 rs5758406 chr22:42076641 A/G cg03806693 chr22:41940476 POLR3H 0.82 9.36 0.45 1.1e-18 Vitiligo; LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.62 -9.88 -0.47 2e-20 Prudent dietary pattern; LIHC cis rs3008870 0.727 rs11208971 chr1:67383901 G/A cg02640540 chr1:67518911 SLC35D1 0.41 6.42 0.33 4.48e-10 Lymphocyte percentage of white cells; LIHC cis rs6502050 0.814 rs62079997 chr17:80076888 C/T cg11859384 chr17:80120422 CCDC57 0.43 5.9 0.3 8.52e-9 Life satisfaction; LIHC cis rs561341 0.843 rs4795666 chr17:30241409 A/G cg13647721 chr17:30228624 UTP6 0.71 7.37 0.37 1.29e-12 Hip circumference adjusted for BMI; LIHC cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.74e-10 Diabetic kidney disease; LIHC cis rs7961581 0.748 rs6581994 chr12:71620269 T/A cg05756094 chr12:71608604 NA 0.38 6.01 0.31 4.78e-9 Type 2 diabetes; LIHC cis rs921968 0.643 rs10187066 chr2:219514759 A/G cg02985541 chr2:219472218 PLCD4 0.44 8.09 0.4 1.08e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04612198 chr11:61880024 NA 0.44 6.07 0.31 3.32e-9 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs9768139 0.935 rs62480865 chr7:158122307 A/C cg25566285 chr7:158114605 PTPRN2 -0.26 -7.69 -0.38 1.58e-13 Calcium levels; LIHC trans rs11098499 1.000 rs28419773 chr4:120211061 T/C cg25214090 chr10:38739885 LOC399744 0.51 7.76 0.39 9.62e-14 Corneal astigmatism; LIHC cis rs11148252 0.875 rs4884452 chr13:52949784 C/T cg00495681 chr13:53174319 NA -0.43 -6.97 -0.35 1.68e-11 Lewy body disease; LIHC cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg00684032 chr4:1343700 KIAA1530 0.51 7.35 0.37 1.43e-12 Obesity-related traits; LIHC cis rs904251 0.965 rs1317563 chr6:37451854 G/T cg01843034 chr6:37503916 NA -0.39 -6.44 -0.33 4.15e-10 Cognitive performance; LIHC trans rs7246657 0.943 rs7255952 chr19:37988797 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.23 0.32 1.34e-9 Coronary artery calcification; LIHC cis rs7666738 0.830 rs6854703 chr4:98977586 A/T cg05340658 chr4:99064831 C4orf37 0.72 13.24 0.58 1.37e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs7131987 0.834 rs11050167 chr12:29426387 C/T cg14222432 chr12:29376421 FAR2 0.37 6.71 0.34 7.99e-11 QT interval; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.02 -23.9 -0.79 6.29e-75 Prudent dietary pattern; LIHC trans rs1945213 0.659 rs17149979 chr11:55840862 A/G cg03929089 chr4:120376271 NA 0.53 6.8 0.35 4.54e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs8180040 0.967 rs4858856 chr3:47565424 G/A cg16586182 chr3:47516702 SCAP -0.43 -7.51 -0.38 5.35e-13 Colorectal cancer; LIHC cis rs60871478 0.679 rs6962050 chr7:817201 A/G cg27478167 chr7:817139 HEATR2 -0.53 -6.94 -0.35 1.93e-11 Cerebrospinal P-tau181p levels; LIHC cis rs8060686 0.641 rs75909028 chr16:68089578 A/C cg05110241 chr16:68378359 PRMT7 -0.6 -6.94 -0.35 2.02e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg27572855 chr1:25598939 RHD 0.4 8.47 0.42 7.21e-16 Plateletcrit;Mean corpuscular volume; LIHC cis rs360798 0.512 rs2430388 chr2:63106784 T/C cg17519650 chr2:63277830 OTX1 0.56 8.46 0.42 8.16e-16 Coronary artery disease; LIHC cis rs2180341 0.722 rs9388555 chr6:127576363 G/A cg27446573 chr6:127587934 RNF146 0.72 10.9 0.51 6.07e-24 Breast cancer; LIHC cis rs6754311 0.773 rs309125 chr2:136643555 C/T cg07305463 chr2:136567211 LCT -0.4 -7.61 -0.38 2.74e-13 Mosquito bite size; LIHC cis rs798554 0.524 rs2283784 chr7:2855337 T/C cg13628971 chr7:2884303 GNA12 0.43 6.78 0.34 5.45e-11 Height; LIHC cis rs908922 0.676 rs7518654 chr1:152517845 C/G cg20991723 chr1:152506922 NA 0.48 8.36 0.41 1.65e-15 Hair morphology; LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg13126279 chr21:47581558 C21orf56 -0.39 -6.05 -0.31 3.75e-9 Testicular germ cell tumor; LIHC cis rs933688 0.509 rs7731341 chr5:90524105 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.37 -5.83 -0.3 1.27e-8 Smoking behavior; LIHC cis rs7208859 0.524 rs11653605 chr17:29088385 T/G cg13385521 chr17:29058706 SUZ12P 0.83 8.21 0.41 4.55e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg02290350 chr8:58132656 NA 0.47 8.61 0.42 2.81e-16 Developmental language disorder (linguistic errors); LIHC cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg20891558 chr2:74357851 NA 0.82 17.09 0.68 9.37e-48 Gestational age at birth (maternal effect); LIHC cis rs116095464 0.510 rs7714944 chr5:231765 C/T cg22857025 chr5:266934 NA -1.51 -18.48 -0.71 2.28e-53 Breast cancer; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs10876993 0.890 rs810204 chr12:58075733 T/C cg15848620 chr12:58087721 OS9 -0.58 -7.96 -0.4 2.5e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.42 -6.0 -0.31 4.95e-9 Longevity; LIHC cis rs9649465 0.807 rs11770249 chr7:123286412 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.18e-15 Migraine; LIHC cis rs6598955 0.670 rs3795685 chr1:26601385 A/G cg04990556 chr1:26633338 UBXN11 0.6 9.93 0.47 1.4e-20 Obesity-related traits; LIHC cis rs17685 0.753 rs1104879 chr7:75685568 C/T cg04610667 chr7:75704037 NA -0.34 -6.22 -0.32 1.45e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2302190 0.882 rs8068135 chr17:56654210 A/C cg05425664 chr17:57184151 TRIM37 -0.46 -5.81 -0.3 1.4e-8 Vitamin D levels; LIHC cis rs929354 0.772 rs3802117 chr7:156987000 C/T cg17757837 chr7:157058334 UBE3C 0.74 12.11 0.55 2.47e-28 Body mass index; LIHC cis rs9814567 1.000 rs9985356 chr3:134232920 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.39 5.95 0.31 6.66e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs78456975 1.000 rs6708604 chr2:1556887 C/T cg01028140 chr2:1542097 TPO -0.56 -6.64 -0.34 1.27e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs4713118 0.513 rs149942 chr6:28001610 T/C cg16479474 chr6:28041457 NA 0.38 6.24 0.32 1.29e-9 Parkinson's disease; LIHC cis rs1775715 0.707 rs2799024 chr10:32166922 A/G cg14930904 chr10:32216787 ARHGAP12 0.34 6.03 0.31 4.17e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9467160 0.520 rs793671 chr6:24438662 C/T cg20631270 chr6:24437470 GPLD1 -0.41 -6.09 -0.31 2.96e-9 Liver enzyme levels; LIHC cis rs8005677 1.000 rs4982706 chr14:23381697 C/T cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs7918232 0.882 rs788237 chr10:27457932 C/T cg14240646 chr10:27532245 ACBD5 0.69 6.4 0.33 5.12e-10 Breast cancer; LIHC cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg07424592 chr7:64974309 NA -0.8 -9.32 -0.45 1.44e-18 Diabetic kidney disease; LIHC cis rs9457247 0.602 rs12209395 chr6:167463914 C/T cg23791538 chr6:167370224 RNASET2 -0.47 -7.04 -0.36 1.05e-11 Crohn's disease; LIHC cis rs7191439 0.657 rs3826076 chr16:88780518 C/T cg27087555 chr16:88793112 FAM38A 1.22 11.53 0.53 3.24e-26 Plateletcrit; LIHC cis rs3106136 0.618 rs6853674 chr4:95309190 T/C cg11021082 chr4:95130006 SMARCAD1 0.35 5.85 0.3 1.13e-8 Capecitabine sensitivity; LIHC cis rs10876993 0.806 rs1689598 chr12:58050500 G/C cg15848620 chr12:58087721 OS9 -0.55 -7.43 -0.37 8.96e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.71 0.76 2.66e-66 Height; LIHC cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg05590025 chr7:65112418 INTS4L2 0.58 6.43 0.33 4.21e-10 Diabetic kidney disease; LIHC cis rs4843747 0.671 rs9933794 chr16:88116981 T/C cg00677901 chr16:88017247 BANP 0.53 7.82 0.39 6.76e-14 Menopause (age at onset); LIHC cis rs67460515 0.892 rs4856757 chr3:160999418 A/T cg03342759 chr3:160939853 NMD3 -0.67 -10.12 -0.48 3.1e-21 Parkinson's disease; LIHC cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg12516959 chr21:47718080 NA -0.42 -6.41 -0.33 4.81e-10 Testicular germ cell tumor; LIHC cis rs1144333 1.000 rs5745354 chr1:76275178 G/A cg03433033 chr1:76189801 ACADM -0.52 -8.1 -0.4 9.77e-15 Attention function in attention deficit hyperactive disorder; LIHC cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.54 8.19 0.41 5.15e-15 Schizophrenia; LIHC cis rs8017423 1.000 rs59052550 chr14:90665098 C/T cg04374321 chr14:90722782 PSMC1 0.74 14.02 0.6 1.37e-35 Mortality in heart failure; LIHC cis rs801193 0.844 rs7779971 chr7:66161790 T/C cg18876405 chr7:65276391 NA 0.43 7.38 0.37 1.24e-12 Aortic root size; LIHC cis rs6138458 0.828 rs6138466 chr20:24997137 A/G cg26195577 chr20:24973756 C20orf3 0.91 11.62 0.53 1.51e-26 Blood protein levels; LIHC cis rs12451471 0.637 rs12452616 chr17:78090081 A/G cg06718696 chr17:78121285 EIF4A3 -0.99 -11.96 -0.54 8.71e-28 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs708547 0.836 rs1718882 chr4:57859533 C/G cg14719990 chr4:57843890 C4orf14;POLR2B 0.42 5.81 0.3 1.4e-8 Response to bleomycin (chromatid breaks); LIHC cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2576037 0.526 rs4890699 chr18:44541029 T/C cg19077165 chr18:44547161 KATNAL2 -0.44 -6.71 -0.34 7.98e-11 Personality dimensions; LIHC cis rs10193935 0.792 rs2053349 chr2:42516205 G/A cg27598129 chr2:42591480 NA -0.67 -10.44 -0.49 2.49e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs4865169 0.560 rs1277311 chr4:57902761 C/T cg16868167 chr4:57843880 C4orf14;POLR2B 0.57 9.65 0.46 1.24e-19 Breast cancer; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs12744310 1.000 rs35529558 chr1:41767022 A/G cg03962019 chr1:41807865 NA 0.38 6.22 0.32 1.46e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs875971 0.862 rs10224872 chr7:65759773 T/A cg18252515 chr7:66147081 NA 0.44 6.33 0.32 7.52e-10 Aortic root size; LIHC trans rs11098499 0.874 rs12509054 chr4:120115075 A/C cg25214090 chr10:38739885 LOC399744 0.45 7.27 0.37 2.49e-12 Corneal astigmatism; LIHC trans rs7395662 0.517 rs10838960 chr11:48584741 A/G cg03929089 chr4:120376271 NA -0.41 -6.09 -0.31 3e-9 HDL cholesterol; LIHC cis rs6545883 0.929 rs2421203 chr2:61669248 C/A cg15711740 chr2:61764176 XPO1 -0.43 -6.0 -0.31 5.07e-9 Tuberculosis; LIHC cis rs317689 0.690 rs10878947 chr12:69642683 A/T cg14784868 chr12:69753453 YEATS4 0.51 7.14 0.36 5.79e-12 Response to diuretic therapy; LIHC cis rs7072216 0.727 rs3750603 chr10:100175536 A/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.09e-10 Metabolite levels; LIHC cis rs1555322 0.530 rs2425042 chr20:33865895 G/A cg17927777 chr20:33865990 NA 0.54 6.35 0.32 6.72e-10 Attention deficit hyperactivity disorder; LIHC cis rs921968 0.643 rs2303561 chr2:219527005 C/T cg18887096 chr2:219472410 PLCD4 -0.39 -6.88 -0.35 2.84e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg06481639 chr22:41940642 POLR3H -0.74 -7.49 -0.38 6.03e-13 Vitiligo; LIHC cis rs4243830 0.850 rs12410405 chr1:6581283 C/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.79 9.81 0.47 3.6e-20 Body mass index; LIHC trans rs2749592 0.531 rs10764134 chr10:37856660 T/C cg17830980 chr10:43048298 ZNF37B 0.42 7.97 0.4 2.42e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs8062405 0.540 rs151226 chr16:28549823 A/C cg00204512 chr16:28754710 NA 0.29 5.85 0.3 1.17e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7089973 0.668 rs61868024 chr10:116637939 A/G cg23260525 chr10:116636907 FAM160B1 0.37 7.28 0.37 2.31e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs2075165 0.836 rs7512751 chr1:156234439 T/G cg07234388 chr1:156261841 TMEM79 0.5 8.91 0.43 3e-17 Tonsillectomy; LIHC cis rs9733 0.596 rs17658705 chr1:150678071 A/C cg15448220 chr1:150897856 SETDB1 -0.39 -6.05 -0.31 3.85e-9 Tonsillectomy; LIHC cis rs7845219 0.525 rs6471501 chr8:95922491 A/G cg16049864 chr8:95962084 TP53INP1 -0.44 -6.56 -0.33 1.95e-10 Type 2 diabetes; LIHC cis rs12744310 0.887 rs35592291 chr1:41791271 G/A cg03962019 chr1:41807865 NA 0.38 6.09 0.31 2.99e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs832540 0.669 rs832538 chr5:56200016 C/T cg22800045 chr5:56110881 MAP3K1 0.44 5.71 0.3 2.41e-8 Coronary artery disease; LIHC cis rs1144333 0.655 rs7418941 chr1:76436020 A/G cg03433033 chr1:76189801 ACADM 0.55 7.82 0.39 6.64e-14 Attention function in attention deficit hyperactive disorder; LIHC trans rs1814175 0.654 rs7482446 chr11:49779020 A/G cg03929089 chr4:120376271 NA -0.9 -18.13 -0.7 5.87e-52 Height; LIHC cis rs35306767 0.903 rs7067865 chr10:908387 C/T cg20503657 chr10:835505 NA 1.09 12.3 0.55 5.01e-29 Eosinophil percentage of granulocytes; LIHC cis rs2439831 0.850 rs12440573 chr15:44108997 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.45 0.42 8.7e-16 Lung cancer in ever smokers; LIHC cis rs4073582 0.595 rs801741 chr11:65917084 A/G cg14036092 chr11:66035641 RAB1B 0.42 6.28 0.32 1.05e-9 Gout; LIHC cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg08888203 chr3:10149979 C3orf24 0.55 6.35 0.32 6.76e-10 Alzheimer's disease; LIHC cis rs11758351 0.587 rs2050950 chr6:26234883 A/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs2455826 0.520 rs2455835 chr3:15754247 A/G cg12698662 chr3:15914712 MIR563 -0.4 -5.83 -0.3 1.29e-8 Inflammatory skin disease; LIHC cis rs8017423 0.967 rs7160032 chr14:90708472 A/G cg04374321 chr14:90722782 PSMC1 0.74 14.17 0.61 3.49e-36 Mortality in heart failure; LIHC trans rs1814175 0.669 rs10839315 chr11:49654406 G/A cg03929089 chr4:120376271 NA -0.54 -9.08 -0.44 8.94e-18 Height; LIHC cis rs28735056 0.620 rs12456484 chr18:77677315 C/G cg20368463 chr18:77673604 PQLC1 0.46 8.12 0.4 8.41e-15 Schizophrenia; LIHC cis rs7666738 0.830 rs7691864 chr4:98971376 G/C cg05340658 chr4:99064831 C4orf37 0.71 13.13 0.58 3.47e-32 Colonoscopy-negative controls vs population controls; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00628130 chr8:95908808 CCNE2 0.54 6.78 0.34 5.44e-11 Lung function (FEV1/FVC); LIHC cis rs7312933 0.576 rs11181364 chr12:42567800 C/T cg17420585 chr12:42539391 GXYLT1 -0.37 -6.0 -0.31 5.07e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17952549 chr19:58983050 ZNF324 0.44 6.27 0.32 1.11e-9 Immature fraction of reticulocytes; LIHC cis rs703842 1.000 rs10877013 chr12:58165085 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.8 12.81 0.57 6.15e-31 Multiple sclerosis; LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs7552404 0.727 rs1144336 chr1:76277421 C/A cg10523679 chr1:76189770 ACADM 0.56 6.98 0.35 1.5e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4808199 1.000 rs12977524 chr19:19568244 A/G cg03709012 chr19:19516395 GATAD2A 1.08 19.38 0.72 5.7e-57 Nonalcoholic fatty liver disease; LIHC cis rs2834256 0.961 rs2251854 chr21:35056247 A/G cg14850771 chr21:34775459 IFNGR2 0.39 6.1 0.31 2.85e-9 Red cell distribution width; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05889321 chr10:97416837 ALDH18A1 0.47 6.89 0.35 2.68e-11 Pancreatic cancer; LIHC cis rs763121 0.815 rs4821799 chr22:39021326 T/G cg06022373 chr22:39101656 GTPBP1 0.65 12.82 0.57 5.39e-31 Menopause (age at onset); LIHC cis rs5769765 1.000 rs2295409 chr22:50261060 G/C cg02269571 chr22:50332266 NA 0.61 8.63 0.42 2.37e-16 Schizophrenia; LIHC cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.26e-51 Menopause (age at onset); LIHC cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.34 -0.45 1.29e-18 Bipolar disorder; LIHC cis rs801193 0.569 rs7800620 chr7:66223688 T/C cg11764359 chr7:65958608 NA 0.74 12.55 0.56 5.46e-30 Aortic root size; LIHC cis rs67981189 0.593 rs7144986 chr14:71473431 C/T cg15816911 chr14:71606274 NA 0.39 6.21 0.32 1.54e-9 Schizophrenia; LIHC cis rs11190604 1.000 rs2495734 chr10:102338686 G/A cg07080220 chr10:102295463 HIF1AN 0.54 7.59 0.38 3e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6840360 0.967 rs4383600 chr4:152694383 T/C cg22705602 chr4:152727874 NA -0.35 -7.43 -0.37 8.48e-13 Intelligence (multi-trait analysis); LIHC cis rs875971 0.895 rs4145009 chr7:65726615 T/C cg18252515 chr7:66147081 NA 0.45 6.4 0.33 5.18e-10 Aortic root size; LIHC cis rs3540 0.618 rs2301832 chr15:91040725 A/T cg22089800 chr15:90895588 ZNF774 -0.58 -8.09 -0.4 1.03e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2749592 0.550 rs10764135 chr10:37866845 C/T cg00409905 chr10:38381863 ZNF37A 0.51 8.63 0.42 2.33e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7927771 1.000 rs2290850 chr11:47807774 T/C cg20307385 chr11:47447363 PSMC3 -0.45 -5.84 -0.3 1.21e-8 Subjective well-being; LIHC trans rs2363709 1.000 rs2363714 chr3:67421846 C/G cg13681781 chr9:139102396 QSOX2 -0.81 -6.33 -0.32 7.66e-10 IgE levels; LIHC cis rs8005677 1.000 rs4981449 chr14:23388871 C/G cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs8027181 0.839 rs11072385 chr15:73020839 A/G cg25996835 chr15:72978165 BBS4;HIGD2B 0.51 7.9 0.39 3.92e-14 Triglyceride levels; LIHC cis rs11864453 0.647 rs9941346 chr16:72135707 C/G cg16558253 chr16:72132732 DHX38 -0.41 -6.6 -0.34 1.61e-10 Fibrinogen levels; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg09033563 chr22:24373618 LOC391322 -0.53 -7.38 -0.37 1.24e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs950169 0.840 rs62019457 chr15:85102142 T/C cg17507749 chr15:85114479 UBE2QP1 0.75 8.88 0.43 3.72e-17 Schizophrenia; LIHC cis rs6500602 0.702 rs3761680 chr16:4524060 C/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.84 0.39 5.61e-14 Schizophrenia; LIHC cis rs9457247 0.740 rs13195812 chr6:167443902 C/T cg12798992 chr6:167411361 FGFR1OP 0.49 7.21 0.36 3.58e-12 Crohn's disease; LIHC cis rs826838 1.000 rs10875717 chr12:38911174 T/C cg26384229 chr12:38710491 ALG10B 0.97 13.1 0.58 4.65e-32 Heart rate; LIHC cis rs477895 0.838 rs35090903 chr11:64000598 C/T cg18225595 chr11:63971243 STIP1 0.66 8.19 0.4 5.24e-15 Mean platelet volume; LIHC cis rs9309711 0.961 rs11678655 chr2:3476234 T/G cg10845886 chr2:3471009 TTC15 -0.63 -12.17 -0.55 1.54e-28 Neurofibrillary tangles; LIHC cis rs12586317 0.511 rs11540758 chr14:35498485 C/T cg05294307 chr14:35346193 BAZ1A -0.5 -7.52 -0.38 4.91e-13 Psoriasis; LIHC cis rs9534288 0.830 rs2296641 chr13:46632226 A/C cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg13395646 chr4:1353034 KIAA1530 0.42 6.57 0.33 1.83e-10 Obesity-related traits; LIHC trans rs875971 0.545 rs4718325 chr7:65680310 G/A cg26939375 chr7:64535504 NA 0.4 6.27 0.32 1.06e-9 Aortic root size; LIHC cis rs7772486 0.754 rs9373476 chr6:146139741 C/G cg13319975 chr6:146136371 FBXO30 -0.36 -6.08 -0.31 3.12e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3736485 0.966 rs11070855 chr15:51850283 C/T cg08986416 chr15:51914746 DMXL2 -0.41 -6.07 -0.31 3.49e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs798554 0.679 rs1614791 chr7:2888057 G/T cg04166393 chr7:2884313 GNA12 0.55 8.65 0.42 2e-16 Height; LIHC cis rs12477438 0.520 rs2309581 chr2:99784292 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.89 -15.04 -0.63 1.38e-39 Chronic sinus infection; LIHC trans rs1973993 0.934 rs588660 chr1:96886604 G/A cg10631902 chr5:14652156 NA 0.32 7.75 0.39 1.05e-13 Weight; LIHC trans rs9641123 0.639 rs2528536 chr7:93245923 G/A cg09745688 chr16:2908918 PRSS22 -0.36 -6.34 -0.32 7.07e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs1023500 0.596 rs133350 chr22:42429049 A/G cg00645731 chr22:42541494 CYP2D7P1 0.41 6.36 0.33 6.52e-10 Schizophrenia; LIHC cis rs2439831 0.867 rs2278860 chr15:43659046 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.74 -10.74 -0.5 2.25e-23 Lung cancer in ever smokers; LIHC trans rs7668874 0.731 rs9784551 chr4:116743086 C/T cg08917878 chr5:172668965 NA -0.31 -6.15 -0.32 2.12e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs344364 0.511 rs2982455 chr16:1950498 T/G cg26897989 chr16:1907736 C16orf73 -0.49 -6.14 -0.32 2.25e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs12477438 1.000 rs12477438 chr2:99841085 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.79 -8.97 -0.44 1.99e-17 Chronic sinus infection; LIHC cis rs5758343 1 rs5758343 chr22:41816652 A/T cg17554472 chr22:41940697 POLR3H 0.54 5.8 0.3 1.48e-8 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2050392 0.517 rs602966 chr10:30755853 C/T cg25182066 chr10:30743637 MAP3K8 -0.67 -11.05 -0.51 1.77e-24 Inflammatory bowel disease; LIHC cis rs758324 0.947 rs2133707 chr5:131181280 C/T cg06307176 chr5:131281290 NA 0.4 5.77 0.3 1.75e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7944584 0.511 rs10838731 chr11:47607135 C/T cg20307385 chr11:47447363 PSMC3 1.01 16.7 0.67 3.3e-46 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs7635838 0.557 rs347615 chr3:11277284 T/A cg00170343 chr3:11313890 ATG7 0.57 9.05 0.44 1.08e-17 HDL cholesterol; LIHC cis rs986417 0.901 rs1024224 chr14:60926942 C/G cg27398547 chr14:60952738 C14orf39 0.81 9.56 0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs1707322 0.752 rs6658700 chr1:46160260 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.26 0.37 2.63e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2727020 0.658 rs4980431 chr11:49350071 G/T cg18944383 chr4:111397179 ENPEP 0.26 6.29 0.32 9.97e-10 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13495574 chr1:173793781 CENPL;DARS2 0.41 6.15 0.32 2.14e-9 Lung function (FEV1/FVC); LIHC cis rs9381040 0.655 rs2268193 chr6:41024625 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.13 -0.31 2.41e-9 Alzheimer's disease (late onset); LIHC trans rs4650994 0.525 rs4650996 chr1:178517365 A/G cg05059571 chr16:84539110 KIAA1609 -0.45 -7.45 -0.37 7.93e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1707322 1.000 rs12060274 chr1:46291062 G/T cg06784218 chr1:46089804 CCDC17 0.35 6.38 0.33 5.9e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs950776 0.518 rs8053 chr15:78841220 T/C cg06917634 chr15:78832804 PSMA4 -0.88 -13.22 -0.58 1.69e-32 Sudden cardiac arrest; LIHC cis rs5769765 0.955 rs8135816 chr22:50291976 G/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.16 -0.44 4.85e-18 Schizophrenia; LIHC cis rs2439831 0.681 rs524527 chr15:43599116 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.89 -16.42 -0.66 4.39e-45 Lung cancer in ever smokers; LIHC cis rs7927771 1.000 rs10838748 chr11:47716381 T/G cg18512352 chr11:47633146 NA -0.25 -5.76 -0.3 1.92e-8 Subjective well-being; LIHC cis rs875971 0.862 rs9791713 chr7:66105198 C/A cg11764359 chr7:65958608 NA -0.76 -12.73 -0.57 1.14e-30 Aortic root size; LIHC cis rs12477438 1.000 rs6732980 chr2:99921613 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.91 -11.09 -0.51 1.23e-24 Chronic sinus infection; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00570391 chr7:815417 HEATR2 0.43 6.39 0.33 5.47e-10 Bilirubin levels; LIHC cis rs7224737 1.000 rs7214921 chr17:40294025 T/C cg00647820 chr17:40259828 DHX58 -0.28 -5.91 -0.3 8.35e-9 Fibrinogen levels; LIHC cis rs4803468 0.967 rs13344547 chr19:41945848 G/T cg14132834 chr19:41945861 ATP5SL 0.45 6.61 0.34 1.5e-10 Height; LIHC cis rs2839186 0.587 rs35679325 chr21:47640980 A/G cg12516959 chr21:47718080 NA 0.4 6.53 0.33 2.39e-10 Testicular germ cell tumor; LIHC cis rs2075371 0.863 rs1646638 chr7:134008706 T/C cg11752832 chr7:134001865 SLC35B4 0.43 6.47 0.33 3.33e-10 Mean platelet volume; LIHC cis rs4910157 1 rs4910157 chr11:8941215 A/G cg12365402 chr11:9010492 NRIP3 0.32 8.35 0.41 1.71e-15 Tonsillectomy; LIHC cis rs17253792 0.822 rs10083493 chr14:56045411 C/T cg01858014 chr14:56050164 KTN1 -0.74 -8.03 -0.4 1.61e-14 Putamen volume; LIHC cis rs2050392 1.000 rs2250714 chr10:30697396 G/C cg25182066 chr10:30743637 MAP3K8 -0.44 -7.01 -0.35 1.28e-11 Inflammatory bowel disease; LIHC cis rs17253792 0.822 rs74824071 chr14:56095142 T/G cg01858014 chr14:56050164 KTN1 -0.78 -8.19 -0.4 5.25e-15 Putamen volume; LIHC cis rs12701220 0.655 rs6955290 chr7:1151066 A/G cg09177884 chr7:1199841 ZFAND2A 0.5 5.9 0.3 8.74e-9 Bronchopulmonary dysplasia; LIHC cis rs17428076 0.836 rs12053046 chr2:172673399 A/G cg13550731 chr2:172543902 DYNC1I2 0.39 6.36 0.33 6.51e-10 Myopia; LIHC cis rs910316 0.737 rs91144 chr14:75449517 G/A cg11812906 chr14:75593930 NEK9 -0.76 -14.45 -0.62 2.76e-37 Height; LIHC cis rs1580019 0.961 rs4320456 chr7:32496003 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs72781680 0.651 rs13019016 chr2:23894773 C/G cg08917208 chr2:24149416 ATAD2B 0.84 7.36 0.37 1.42e-12 Lymphocyte counts; LIHC cis rs2304069 0.837 rs10041451 chr5:149385197 A/C cg12661370 chr5:149340060 SLC26A2 0.5 6.06 0.31 3.58e-9 HIV-1 control; LIHC cis rs2760061 0.598 rs673726 chr1:228120173 T/C cg01200585 chr1:228362443 C1orf69 -0.39 -5.85 -0.3 1.17e-8 Diastolic blood pressure; LIHC trans rs28735056 0.584 rs11664834 chr18:77644876 G/T cg05926928 chr17:57297772 GDPD1 0.69 8.66 0.42 1.83e-16 Schizophrenia; LIHC cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg00091569 chr3:40428383 ENTPD3 0.36 6.0 0.31 4.92e-9 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs2305522 chr3:40429358 A/G cg00656387 chr3:40428638 ENTPD3 0.41 6.85 0.35 3.4e-11 Renal cell carcinoma; LIHC cis rs950169 0.922 rs12915832 chr15:85111457 C/T cg12863693 chr15:85201151 NMB 0.41 5.77 0.3 1.77e-8 Schizophrenia; LIHC cis rs1348850 0.668 rs13034886 chr2:178493301 G/T cg27490568 chr2:178487706 NA 0.7 9.37 0.45 1.04e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs7246657 0.943 rs2112923 chr19:37940327 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC trans rs62103177 0.525 rs10438902 chr18:77745640 A/G cg05926928 chr17:57297772 GDPD1 -0.57 -6.5 -0.33 2.77e-10 Opioid sensitivity; LIHC cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.89 -0.51 6.7e-24 Platelet count; LIHC cis rs11958404 0.860 rs6868830 chr5:157442187 T/C cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs11122272 0.735 rs2491403 chr1:231511185 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs12477438 0.765 rs4374423 chr2:99662348 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs12497850 1.000 rs1352420 chr3:48757291 A/G cg20833759 chr3:49053208 WDR6;DALRD3 0.41 5.93 0.31 7.53e-9 Parkinson's disease; LIHC cis rs73001065 0.591 rs2285626 chr19:19467545 C/T cg03709012 chr19:19516395 GATAD2A 0.77 8.73 0.43 1.16e-16 LDL cholesterol; LIHC cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs919433 0.679 rs13000656 chr2:198522126 T/C cg10820045 chr2:198174542 NA -0.48 -7.4 -0.37 1.04e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs34375054 0.558 rs67041765 chr12:125672913 T/G cg25124228 chr12:125621409 AACS -0.47 -8.02 -0.4 1.69e-14 Post bronchodilator FEV1/FVC ratio; LIHC cis rs7116495 1.000 rs635701 chr11:71554921 A/G cg26138937 chr11:71823887 C11orf51 0.64 5.88 0.3 9.52e-9 Severe influenza A (H1N1) infection; LIHC cis rs2239547 0.657 rs2072391 chr3:52862200 C/T cg11645453 chr3:52864694 ITIH4 0.34 8.83 0.43 5.49e-17 Schizophrenia; LIHC cis rs12908161 1.000 rs12910012 chr15:85298662 T/C cg12863693 chr15:85201151 NMB 0.44 6.31 0.32 8.81e-10 Schizophrenia; LIHC cis rs2153535 0.580 rs1932276 chr6:8442593 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs7903847 0.596 rs10882934 chr10:99170995 T/G cg20016023 chr10:99160130 RRP12 -0.43 -7.06 -0.36 9.6e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs910316 0.763 rs735452 chr14:75497984 A/G cg11812906 chr14:75593930 NEK9 -0.79 -15.1 -0.63 7.88e-40 Height; LIHC cis rs17685 0.753 rs55812043 chr7:75747241 T/C cg04610667 chr7:75704037 NA -0.34 -6.09 -0.31 3.04e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3018712 0.532 rs7116363 chr11:68412798 G/A cg16797656 chr11:68205561 LRP5 -0.46 -6.04 -0.31 4.09e-9 Total body bone mineral density; LIHC cis rs2439831 1.000 rs2253708 chr15:43797273 G/C cg15269541 chr15:43626905 ADAL -0.3 -5.88 -0.3 9.76e-9 Lung cancer in ever smokers; LIHC cis rs12908161 1.000 rs12908161 chr15:85207825 A/G cg03959625 chr15:84868606 LOC388152 0.43 5.9 0.3 8.86e-9 Schizophrenia; LIHC cis rs9911578 1.000 rs7207693 chr17:57016525 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs4908760 0.759 rs6577514 chr1:8712743 T/G cg20416874 chr1:8611966 RERE -0.63 -12.8 -0.57 6.2e-31 Vitiligo; LIHC cis rs7552404 1.000 rs4949872 chr1:76131392 C/G cg03433033 chr1:76189801 ACADM 0.67 9.4 0.45 7.91e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs897984 0.646 rs9938088 chr16:30830004 G/A cg00531865 chr16:30841666 NA -0.4 -6.29 -0.32 9.82e-10 Dementia with Lewy bodies; LIHC cis rs7772486 0.846 rs9376976 chr6:146355605 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.06e-11 Alzheimer's disease; LIHC cis rs9399135 0.967 rs6910530 chr6:135332770 C/T cg22676075 chr6:135203613 NA 0.39 6.37 0.33 6.26e-10 Red blood cell count; LIHC cis rs3806843 1.000 rs2240695 chr5:140168151 G/T cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs4788570 0.585 rs7499576 chr16:71789553 T/G cg06353428 chr16:71660113 MARVELD3 1.38 14.61 0.62 6.57e-38 Intelligence (multi-trait analysis); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg24093715 chr4:47983620 CNGA1 0.33 6.12 0.31 2.49e-9 Hepatitis; LIHC cis rs918629 0.530 rs9314162 chr5:95252594 C/A cg10483112 chr5:95245456 ELL2 -0.38 -7.0 -0.35 1.37e-11 IgG glycosylation; LIHC cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg06238570 chr21:40685208 BRWD1 -0.62 -7.58 -0.38 3.22e-13 Cognitive function; LIHC cis rs7726839 0.507 rs60068988 chr5:597668 T/C cg09021430 chr5:549028 NA -0.42 -8.36 -0.41 1.65e-15 Obesity-related traits; LIHC cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs6964587 0.839 rs6952459 chr7:91435820 T/A cg17063962 chr7:91808500 NA 0.96 17.24 0.68 2.29e-48 Breast cancer; LIHC cis rs7909074 0.865 rs10900123 chr10:45376574 C/T cg05187965 chr10:45406764 TMEM72 -0.26 -6.47 -0.33 3.42e-10 Mean corpuscular volume; LIHC cis rs61677309 0.558 rs4245179 chr11:118144445 A/G cg06090739 chr11:118230722 UBE4A 0.32 6.03 0.31 4.34e-9 Lung cancer in ever smokers; LIHC cis rs12477438 0.834 rs11903311 chr2:99701807 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -10.57 -0.5 8.92e-23 Chronic sinus infection; LIHC cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.1 -0.48 3.53e-21 Platelet count; LIHC cis rs7122539 0.603 rs508443 chr11:66509369 C/T cg24851651 chr11:66362959 CCS -0.36 -6.28 -0.32 1.05e-9 HIV-1 susceptibility; LIHC cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg17554472 chr22:41940697 POLR3H -0.54 -5.87 -0.3 1.05e-8 Vitiligo; LIHC cis rs9457247 0.967 rs1187532 chr6:167382020 G/A cg12798992 chr6:167411361 FGFR1OP 0.59 9.73 0.47 6.7e-20 Crohn's disease; LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg07167872 chr1:205819463 PM20D1 -0.59 -8.59 -0.42 3.24e-16 Menarche (age at onset); LIHC cis rs2066819 1.000 rs77120931 chr12:56646213 A/C cg26714650 chr12:56694279 CS -1.29 -12.34 -0.55 3.55e-29 Psoriasis vulgaris; LIHC cis rs6502050 0.634 rs11077973 chr17:80095191 C/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.59e-9 Life satisfaction; LIHC cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg03264133 chr6:25882463 NA -1.02 -13.53 -0.59 1.1e-33 Intelligence (multi-trait analysis); LIHC cis rs9393692 0.875 rs9358917 chr6:26284417 T/C cg13736514 chr6:26305472 NA -0.37 -6.23 -0.32 1.34e-9 Educational attainment; LIHC cis rs9517320 0.534 rs61971163 chr13:99188883 G/A cg20487152 chr13:99095054 FARP1 -0.38 -6.21 -0.32 1.5e-9 Longevity; LIHC trans rs62103177 0.810 rs62103195 chr18:77629693 T/C cg05926928 chr17:57297772 GDPD1 1.14 11.65 0.53 1.23e-26 Opioid sensitivity; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg07002622 chr6:118822466 C6orf204;BRD7P3 -0.57 -6.22 -0.32 1.49e-9 Diastolic blood pressure; LIHC cis rs5758511 0.680 rs1033460 chr22:42619308 A/G cg20195005 chr22:42527684 CYP2D6 0.31 5.96 0.31 6.14e-9 Birth weight; LIHC cis rs240764 0.817 rs240147 chr6:101078300 G/A cg09795085 chr6:101329169 ASCC3 0.53 7.45 0.37 7.93e-13 Neuroticism; LIHC trans rs950169 0.649 rs12901010 chr15:84699034 G/A cg24036039 chr1:3397125 ARHGEF16 0.39 6.21 0.32 1.57e-9 Schizophrenia; LIHC cis rs6912958 0.781 rs3934838 chr6:88284699 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC cis rs2439831 0.681 rs2278859 chr15:43632960 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.75 11.25 0.52 3.29e-25 Lung cancer in ever smokers; LIHC cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg11905131 chr22:24372483 LOC391322 -0.65 -9.27 -0.45 2.15e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8060686 0.545 rs76495028 chr16:68177036 G/C cg05110241 chr16:68378359 PRMT7 -0.63 -6.85 -0.35 3.34e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs7772486 0.875 rs9373483 chr6:146364194 A/G cg13319975 chr6:146136371 FBXO30 -0.34 -5.74 -0.3 2.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs17001868 0.568 rs3788579 chr22:40742989 T/C cg07138101 chr22:40742427 ADSL 0.55 6.46 0.33 3.62e-10 Mammographic density (dense area); LIHC cis rs10857712 0.521 rs10857714 chr10:135235370 C/A cg01444801 chr10:135216882 MTG1 -0.52 -8.46 -0.42 7.93e-16 Systemic lupus erythematosus; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22772771 chr6:159420466 RSPH3 0.48 6.96 0.35 1.77e-11 Cognitive function; LIHC cis rs72627123 0.867 rs74635757 chr14:74489225 C/T cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 6.03 0.31 4.28e-9 Morning vs. evening chronotype; LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg07341007 chr3:195489909 MUC4 0.45 8.0 0.4 1.96e-14 Lung disease severity in cystic fibrosis; LIHC cis rs240764 0.658 rs9390679 chr6:101216102 C/T cg09795085 chr6:101329169 ASCC3 -0.41 -5.73 -0.3 2.19e-8 Neuroticism; LIHC cis rs3751667 0.506 rs4984718 chr16:974411 T/A cg06835404 chr16:988973 LMF1 0.43 7.95 0.39 2.74e-14 Non-glioblastoma glioma;Glioblastoma;Glioma; LIHC cis rs9948 0.786 rs62152775 chr2:97448474 G/T cg01990225 chr2:97406019 LMAN2L -0.73 -6.31 -0.32 8.85e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7246657 0.943 rs10426666 chr19:37828514 C/G cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC cis rs8017423 0.647 rs4900037 chr14:90821478 A/G cg04374321 chr14:90722782 PSMC1 0.49 7.38 0.37 1.18e-12 Mortality in heart failure; LIHC cis rs12220238 0.818 rs115350439 chr10:75899365 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.71 7.01 0.35 1.27e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs208520 1.000 rs28773210 chr6:66993566 C/T cg07460842 chr6:66804631 NA 0.68 7.32 0.37 1.8e-12 Exhaled nitric oxide output; LIHC cis rs1559088 0.947 rs7259879 chr19:33549462 T/C cg27124370 chr19:33622961 WDR88 0.47 7.14 0.36 5.54e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs9951602 0.512 rs9946123 chr18:76654557 A/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs12478296 1.000 rs12469535 chr2:243044147 G/A cg18898632 chr2:242989856 NA -0.57 -7.68 -0.38 1.66e-13 Obesity-related traits; LIHC cis rs6598955 0.670 rs12733645 chr1:26540356 G/T cg04990556 chr1:26633338 UBXN11 -0.56 -9.09 -0.44 8.38e-18 Obesity-related traits; LIHC cis rs892961 0.806 rs35489990 chr17:75412312 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs55665837 1.000 rs12364959 chr11:14507435 T/C cg19336497 chr11:14380999 RRAS2 -0.45 -8.21 -0.41 4.71e-15 Vitamin D levels; LIHC cis rs7617773 0.963 rs12494304 chr3:48178029 C/T cg11946769 chr3:48343235 NME6 -0.53 -7.12 -0.36 6.52e-12 Coronary artery disease; LIHC cis rs2072499 0.966 rs2853641 chr1:156181770 A/G cg25208724 chr1:156163844 SLC25A44 0.74 13.05 0.58 7.03e-32 Testicular germ cell tumor; LIHC cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg08499158 chr17:42289980 UBTF 0.54 9.6 0.46 1.78e-19 Total body bone mineral density; LIHC cis rs11583043 1.000 rs11584222 chr1:101480110 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.58 7.83 0.39 6.12e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs831571 1.000 rs17069791 chr3:64052279 G/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.58 -6.34 -0.32 7.18e-10 Type 2 diabetes; LIHC cis rs7534824 0.625 rs61780288 chr1:101389945 T/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 6.9 0.35 2.61e-11 Refractive astigmatism; LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg14709524 chr16:89940631 TCF25 0.54 7.17 0.36 4.57e-12 Skin colour saturation; LIHC cis rs10464366 0.746 rs17171537 chr7:39145647 C/T cg15212455 chr7:39170539 POU6F2 0.47 8.18 0.4 5.69e-15 IgG glycosylation; LIHC trans rs8073060 0.544 rs225287 chr17:33929487 G/T cg19694781 chr19:47549865 TMEM160 -1.22 -12.51 -0.56 7.75e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs2727020 0.563 rs10769582 chr11:49474040 T/C cg15704280 chr7:45808275 SEPT13 -0.97 -20.64 -0.74 4.98e-62 Coronary artery disease; LIHC cis rs2439831 0.702 rs16977724 chr15:44151299 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.43 0.41 1.01e-15 Lung cancer in ever smokers; LIHC cis rs2842992 0.789 rs7765490 chr6:160204326 C/T cg11366901 chr6:160182831 ACAT2 0.87 14.35 0.61 6.76e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg06238570 chr21:40685208 BRWD1 -0.55 -6.73 -0.34 7.16e-11 Cognitive function; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg11060661 chr22:24314208 DDT;DDTL -0.57 -10.02 -0.48 6.65e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7131987 0.934 rs2216854 chr12:29423460 G/A cg21486233 chr12:29375141 FAR2 0.3 5.96 0.31 6.42e-9 QT interval; LIHC trans rs7618501 1.000 rs7618519 chr3:49772708 A/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.71 -0.34 7.95e-11 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.693 rs10950413 chr7:1912988 A/G cg02951883 chr7:2050386 MAD1L1 -0.5 -7.39 -0.37 1.12e-12 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg26338869 chr17:61819248 STRADA -0.61 -8.95 -0.44 2.25e-17 Prudent dietary pattern; LIHC cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg10802521 chr3:52805072 NEK4 -0.44 -7.54 -0.38 4.16e-13 Bipolar disorder; LIHC cis rs10464366 0.746 rs6945402 chr7:39145385 A/T cg15212455 chr7:39170539 POU6F2 0.46 8.19 0.4 5.38e-15 IgG glycosylation; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg06873352 chr17:61820015 STRADA 0.72 12.42 0.56 1.71e-29 Prudent dietary pattern; LIHC cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg25072359 chr17:41440525 NA 0.38 6.12 0.31 2.63e-9 Menopause (age at onset); LIHC cis rs9457247 0.508 rs9459874 chr6:167504127 A/G cg23791538 chr6:167370224 RNASET2 0.45 7.52 0.38 5.03e-13 Crohn's disease; LIHC cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 11.88 0.54 1.75e-27 Alzheimer's disease; LIHC cis rs10751667 0.643 rs7396951 chr11:927355 G/A cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC cis rs6121246 0.697 rs6087716 chr20:30229040 C/T cg13852791 chr20:30311386 BCL2L1 0.82 8.28 0.41 2.77e-15 Mean corpuscular hemoglobin; LIHC cis rs6061231 0.793 rs6061512 chr20:60976929 G/A cg22601191 chr20:60968625 CABLES2 0.45 5.81 0.3 1.4e-8 Colorectal cancer; LIHC cis rs10131894 0.611 rs175001 chr14:75436452 A/C cg11812906 chr14:75593930 NEK9 0.67 11.39 0.52 1.08e-25 Coronary artery disease; LIHC cis rs9768139 0.566 rs729099 chr7:158114152 C/T cg25566285 chr7:158114605 PTPRN2 0.22 5.72 0.3 2.36e-8 Calcium levels; LIHC trans rs9350100 0.806 rs9477970 chr6:19082663 T/A cg18972584 chr15:25476056 SNORD115-15;SNORD115-21;SNORD115-33;SNORD115-34 0.32 6.09 0.31 3.05e-9 Age at voice drop; LIHC cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg11644478 chr21:40555479 PSMG1 0.85 10.81 0.5 1.31e-23 Cognitive function; LIHC cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg08888203 chr3:10149979 C3orf24 0.53 6.45 0.33 3.91e-10 Alzheimer's disease; LIHC cis rs2806561 1.000 rs654585 chr1:23514714 T/C cg19743168 chr1:23544995 NA 0.38 7.1 0.36 7.17e-12 Height; LIHC cis rs1005277 0.522 rs7072977 chr10:37940440 C/A cg25427524 chr10:38739819 LOC399744 -0.61 -11.58 -0.53 2.16e-26 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg07677032 chr17:61819896 STRADA 0.43 6.22 0.32 1.47e-9 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10974104 chr11:119076790 CBL -0.42 -6.28 -0.32 1.01e-9 Pancreatic cancer; LIHC cis rs9911578 1.000 rs11870671 chr17:56605360 A/G cg12560992 chr17:57184187 TRIM37 -0.98 -17.73 -0.69 2.34e-50 Intelligence (multi-trait analysis); LIHC cis rs7085104 0.591 rs4919683 chr10:104585125 G/T cg15744005 chr10:104629667 AS3MT -0.4 -9.11 -0.44 6.87e-18 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC cis rs11764590 0.694 rs6977161 chr7:2099361 T/C cg23422044 chr7:1970798 MAD1L1 -0.55 -8.76 -0.43 9.2e-17 Neuroticism; LIHC cis rs710216 0.843 rs2297972 chr1:43418026 C/T cg03128534 chr1:43423976 SLC2A1 -0.51 -7.25 -0.36 2.88e-12 Red cell distribution width; LIHC cis rs72781680 1.000 rs111229211 chr2:24167417 T/G cg08917208 chr2:24149416 ATAD2B 0.86 7.79 0.39 7.84e-14 Lymphocyte counts; LIHC cis rs7208859 0.673 rs11080138 chr17:29224542 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7523273 0.606 rs2796266 chr1:207922945 C/T cg22525895 chr1:207977042 MIR29B2 -0.67 -10.84 -0.51 9.69e-24 Schizophrenia; LIHC cis rs67311347 0.549 rs60249586 chr3:40246659 G/A cg18306943 chr3:40428807 ENTPD3 0.39 6.44 0.33 4.02e-10 Renal cell carcinoma; LIHC cis rs765787 0.530 rs2554455 chr15:45521304 T/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.73 -0.3 2.15e-8 Uric acid levels; LIHC cis rs2303745 0.622 rs1864113 chr19:17393504 G/C cg02221750 chr19:17393354 ANKLE1 -0.41 -5.91 -0.3 8.49e-9 Systemic lupus erythematosus; LIHC cis rs2334880 0.678 rs12919092 chr16:71446490 T/C cg06353428 chr16:71660113 MARVELD3 -0.88 -8.03 -0.4 1.62e-14 Malaria; LIHC cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.85 0.35 3.49e-11 Mean corpuscular hemoglobin; LIHC cis rs10883723 0.810 rs7093028 chr10:104259417 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4423214 0.569 rs4944044 chr11:71120213 G/A cg05163923 chr11:71159392 DHCR7 0.74 11.17 0.52 6.34e-25 Vitamin D levels; LIHC cis rs9393692 0.905 rs9393694 chr6:26279296 T/C cg05868516 chr6:26286170 HIST1H4H 0.41 6.31 0.32 8.62e-10 Educational attainment; LIHC cis rs7772486 0.790 rs2265918 chr6:146219164 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.85 0.3 1.16e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC cis rs9858542 1.000 rs13085791 chr3:49721798 C/A cg03060546 chr3:49711283 APEH -0.64 -8.72 -0.43 1.22e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg11494091 chr17:61959527 GH2 0.44 8.08 0.4 1.11e-14 Prudent dietary pattern; LIHC cis rs17818399 0.749 rs4142759 chr2:46783890 A/G cg02822958 chr2:46747628 ATP6V1E2 0.48 7.18 0.36 4.32e-12 Height; LIHC cis rs4665809 1.000 rs1550382 chr2:26266877 T/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.68 -0.42 1.68e-16 Gut microbiome composition (summer); LIHC cis rs6831352 0.879 rs17218003 chr4:100054723 G/C cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.814 rs1619652 chr11:111469757 G/A cg09085632 chr11:111637200 PPP2R1B -0.94 -11.37 -0.52 1.23e-25 Primary sclerosing cholangitis; LIHC cis rs7635838 0.892 rs12163566 chr3:11483096 T/A cg00170343 chr3:11313890 ATG7 0.42 6.61 0.34 1.45e-10 HDL cholesterol; LIHC cis rs1580019 0.563 rs13225132 chr7:32800975 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.58 8.23 0.41 3.95e-15 Cognitive ability; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25506325 chr7:2093962 MAD1L1 -0.41 -6.24 -0.32 1.32e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.13 0.55 2e-28 Prudent dietary pattern; LIHC cis rs7647973 1.000 rs892974 chr3:49398514 C/A cg07636037 chr3:49044803 WDR6 0.51 6.1 0.31 2.89e-9 Menarche (age at onset); LIHC cis rs2832191 0.671 rs73346699 chr21:30515529 C/T cg08807101 chr21:30365312 RNF160 -0.44 -6.33 -0.32 7.61e-10 Dental caries; LIHC cis rs7224737 1.000 rs1869365 chr17:40293865 T/C cg00647820 chr17:40259828 DHX58 -0.29 -6.16 -0.32 2.08e-9 Fibrinogen levels; LIHC cis rs3806843 0.808 rs6893708 chr5:140125922 T/C cg26395211 chr5:140044315 WDR55 0.38 5.74 0.3 2.08e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.15 -0.32 2.22e-9 Aortic root size; LIHC cis rs34779708 0.966 rs4934732 chr10:35431684 T/C cg04310649 chr10:35416472 CREM -0.42 -5.78 -0.3 1.65e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg06466757 chr4:1255808 NA 0.34 5.75 0.3 2e-8 Obesity-related traits; LIHC cis rs9628987 0.500 rs12079653 chr1:8430594 C/A cg20416874 chr1:8611966 RERE 0.5 5.82 0.3 1.33e-8 Breast cancer; LIHC cis rs614226 1.000 rs563920 chr12:121017439 A/G cg27489772 chr12:121021490 NA 0.53 5.84 0.3 1.23e-8 Type 1 diabetes nephropathy; LIHC cis rs1580019 0.563 rs34201720 chr7:32568935 G/A cg14728415 chr7:32535168 LSM5;AVL9 0.41 5.84 0.3 1.19e-8 Cognitive ability; LIHC cis rs1577917 0.739 rs2758846 chr6:86349570 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -8.01 -0.4 1.84e-14 Response to antipsychotic treatment; LIHC cis rs1728785 1.000 rs7195979 chr16:68586801 G/A cg02972257 chr16:68554789 NA -0.55 -6.15 -0.32 2.11e-9 Ulcerative colitis; LIHC trans rs7714584 1.000 rs2344180 chr5:150267357 T/A cg20675040 chr8:143813288 C8orf55 0.33 6.07 0.31 3.46e-9 Crohn's disease; LIHC cis rs11098499 0.789 rs12498994 chr4:120250818 A/C cg09307838 chr4:120376055 NA 0.71 11.25 0.52 3.29e-25 Corneal astigmatism; LIHC cis rs10791097 0.694 rs7940027 chr11:130745591 A/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7208859 0.623 rs216433 chr17:28921860 T/C cg14067834 chr17:29058358 SUZ12P 0.65 6.78 0.34 5.15e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg08677398 chr8:58056175 NA -0.41 -6.31 -0.32 8.8e-10 Developmental language disorder (linguistic errors); LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.61 8.65 0.42 1.97e-16 Lymphocyte counts; LIHC cis rs10911363 0.571 rs6424897 chr1:183419203 T/C cg09173681 chr1:183549694 NCF2 -0.54 -9.53 -0.46 3.04e-19 Systemic lupus erythematosus; LIHC cis rs4888262 0.514 rs8048239 chr16:74578317 A/T cg01733217 chr16:74700730 RFWD3 0.79 15.33 0.64 9.8e-41 Testicular germ cell tumor; LIHC cis rs798554 1.000 rs798548 chr7:2760935 A/G cg19717773 chr7:2847554 GNA12 -0.41 -6.61 -0.34 1.45e-10 Height; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.66 9.41 0.45 7.5e-19 Lymphocyte counts; LIHC cis rs7520050 0.931 rs7526678 chr1:46374159 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.73 0.3 2.16e-8 Red blood cell count;Reticulocyte count; LIHC cis rs6815814 0.861 rs73142654 chr4:38785697 T/A cg06935464 chr4:38784597 TLR10 0.53 9.36 0.45 1.07e-18 Breast cancer; LIHC cis rs13394619 0.565 rs12478958 chr2:11748037 A/G cg07314298 chr2:11723111 GREB1 -0.36 -6.27 -0.32 1.11e-9 Endometriosis; LIHC cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs1555322 0.530 rs6060347 chr20:33874151 A/G cg03689076 chr20:33865952 NA 0.54 6.37 0.33 6.12e-10 Attention deficit hyperactivity disorder; LIHC cis rs3806843 1.000 rs2879089 chr5:140191893 A/T cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9814567 0.896 rs6790338 chr3:134208167 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.81 -0.3 1.46e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs61677309 0.964 rs55798741 chr11:118154114 G/T cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs7020830 0.505 rs12553878 chr9:37095705 C/T cg14294708 chr9:37120828 ZCCHC7 0.68 12.4 0.56 2.1e-29 Schizophrenia; LIHC cis rs17685 0.753 rs2302438 chr7:75677065 C/A cg04610667 chr7:75704037 NA -0.34 -6.17 -0.32 1.91e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs916888 0.773 rs199451 chr17:44801784 G/A cg15921436 chr17:44337874 NA 0.65 6.58 0.34 1.75e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2576037 0.526 rs1539878 chr18:44523004 T/C cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.98e-10 Personality dimensions; LIHC cis rs7659604 0.605 rs2071486 chr4:122740162 C/T cg20573242 chr4:122745356 CCNA2 0.51 7.96 0.4 2.56e-14 Type 2 diabetes; LIHC cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg18252515 chr7:66147081 NA -1.28 -17.02 -0.68 1.74e-47 Diabetic kidney disease; LIHC cis rs6499255 0.904 rs7194753 chr16:69564364 A/G cg15192750 chr16:69999425 NA -0.45 -6.73 -0.34 7.09e-11 IgE levels; LIHC cis rs116095464 0.558 rs56342538 chr5:225796 T/C cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg00091569 chr3:40428383 ENTPD3 -0.39 -6.53 -0.33 2.32e-10 Renal cell carcinoma; LIHC cis rs4589502 1.000 rs8023363 chr15:67154654 G/A cg09911534 chr15:67153556 NA -0.45 -6.0 -0.31 5.02e-9 Lung cancer (smoking interaction); LIHC cis rs1153858 0.848 rs9806699 chr15:45740392 G/A cg21132104 chr15:45694354 SPATA5L1 0.36 5.97 0.31 5.83e-9 Homoarginine levels; LIHC cis rs9527 0.614 rs4919691 chr10:104624475 A/C cg15744005 chr10:104629667 AS3MT -0.42 -9.49 -0.46 4.1e-19 Arsenic metabolism; LIHC cis rs2072499 0.833 rs2758605 chr1:156200445 G/C cg25208724 chr1:156163844 SLC25A44 0.6 10.34 0.49 5.38e-22 Testicular germ cell tumor; LIHC cis rs1552244 0.554 rs58020561 chr3:10054682 A/G cg21531657 chr3:10005747 TMEM111 0.39 5.76 0.3 1.92e-8 Alzheimer's disease; LIHC cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg27572855 chr1:25598939 RHD 0.43 9.66 0.46 1.11e-19 Erythrocyte sedimentation rate; LIHC cis rs1000083 0.666 rs2697598 chr5:96633928 C/T ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs7923837 0.713 rs10882099 chr10:94460650 T/C cg25506282 chr10:94462361 NA 0.38 6.76 0.34 6.14e-11 Body mass index;Multiple sclerosis; LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs1789 0.903 rs6850422 chr4:15682437 C/T cg16509355 chr4:15471240 CC2D2A -0.46 -6.94 -0.35 1.99e-11 Blood protein levels; LIHC cis rs7572733 0.555 rs6434953 chr2:198929693 A/G cg10820045 chr2:198174542 NA 0.41 6.03 0.31 4.23e-9 Dermatomyositis; LIHC cis rs9325144 0.555 rs4550281 chr12:38689937 A/G cg26384229 chr12:38710491 ALG10B 0.57 7.94 0.39 2.89e-14 Morning vs. evening chronotype; LIHC cis rs7914558 1.000 rs943036 chr10:104836047 T/C cg15744005 chr10:104629667 AS3MT -0.37 -8.39 -0.41 1.29e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7044106 0.762 rs1547268 chr9:123408688 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.83 0.39 6.05e-14 Hip circumference adjusted for BMI; LIHC trans rs4714291 0.963 rs847759 chr6:40024483 G/A cg02267698 chr19:7991119 CTXN1 0.39 6.21 0.32 1.56e-9 Strep throat; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg08280861 chr8:58055591 NA 0.51 6.39 0.33 5.56e-10 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.712 rs60232511 chr7:75800082 A/G cg16684958 chr7:75615977 POR 0.52 8.57 0.42 3.5e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg10755058 chr3:40428713 ENTPD3 0.41 6.92 0.35 2.29e-11 Renal cell carcinoma; LIHC cis rs332507 0.830 rs3772787 chr3:124395368 G/C cg05980111 chr3:124395277 KALRN 0.45 6.72 0.34 7.51e-11 Plateletcrit; LIHC cis rs7223966 0.921 rs67018565 chr17:61928055 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.66 0.34 1.08e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1577917 0.655 rs7742691 chr6:86278691 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.33 0.32 7.89e-10 Response to antipsychotic treatment; LIHC cis rs853679 0.517 rs56364346 chr6:28050762 T/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs7582180 0.701 rs11693044 chr2:100922313 T/C cg14675211 chr2:100938903 LONRF2 0.51 8.05 0.4 1.36e-14 Intelligence (multi-trait analysis); LIHC cis rs10792665 0.512 rs7928466 chr11:82596733 T/G cg24227371 chr11:82718527 RAB30 -0.28 -6.59 -0.34 1.68e-10 Obesity-related traits; LIHC trans rs6500602 0.963 rs7201012 chr16:4480682 C/G cg05791018 chr13:19965014 NA -0.3 -6.57 -0.33 1.86e-10 Schizophrenia; LIHC cis rs1577917 0.958 rs10944147 chr6:86550786 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.46 -0.37 7.34e-13 Response to antipsychotic treatment; LIHC cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.6 0.46 1.76e-19 Bipolar disorder; LIHC cis rs11031096 0.811 rs4910599 chr11:4156040 T/A cg18678763 chr11:4115507 RRM1 -0.53 -8.08 -0.4 1.14e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9420 0.925 rs78587207 chr11:57654991 T/G cg19752551 chr11:57585705 CTNND1 -0.46 -6.37 -0.33 6.21e-10 Schizophrenia; LIHC trans rs1814175 0.645 rs866427 chr11:49923853 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC trans rs561341 1.000 rs564714 chr17:30318404 C/T cg20587970 chr11:113659929 NA -1.47 -12.07 -0.55 3.44e-28 Hip circumference adjusted for BMI; LIHC cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg13047869 chr3:10149882 C3orf24 0.5 6.12 0.31 2.62e-9 Alzheimer's disease; LIHC cis rs7772486 0.875 rs7766595 chr6:146364507 A/T cg23711669 chr6:146136114 FBXO30 0.6 10.67 0.5 3.87e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg07677032 chr17:61819896 STRADA 0.42 6.09 0.31 2.96e-9 Prudent dietary pattern; LIHC cis rs826838 0.967 rs11169142 chr12:39085773 A/T cg26384229 chr12:38710491 ALG10B -0.59 -8.96 -0.44 2.07e-17 Heart rate; LIHC cis rs875971 1.000 rs7783613 chr7:65805261 C/T cg11764359 chr7:65958608 NA -0.91 -16.95 -0.68 3.19e-47 Aortic root size; LIHC cis rs4891159 0.790 rs4891018 chr18:74127082 A/T cg24786174 chr18:74118243 ZNF516 -0.77 -14.18 -0.61 3.16e-36 Longevity; LIHC cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg03517284 chr6:25882590 NA -0.44 -6.71 -0.34 8.23e-11 Height; LIHC cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg10360139 chr7:1886902 MAD1L1 -0.4 -6.23 -0.32 1.38e-9 Bipolar disorder and schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04721582 chr2:178257292 LOC100130691;AGPS 0.45 6.25 0.32 1.19e-9 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05320259 chr20:25370897 ABHD12 0.44 6.54 0.33 2.25e-10 Pancreatic cancer; LIHC cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg20887711 chr4:1340912 KIAA1530 0.78 12.0 0.54 6.26e-28 Longevity; LIHC trans rs801193 0.761 rs2659888 chr7:66230171 T/G cg26939375 chr7:64535504 NA 0.43 6.83 0.35 3.81e-11 Aortic root size; LIHC cis rs881375 0.933 rs2239657 chr9:123671520 A/G cg14580859 chr9:123691850 NA -0.37 -6.55 -0.33 2.14e-10 Rheumatoid arthritis; LIHC cis rs68092024 0.704 rs704576 chr3:99487154 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.91 0.3 8.09e-9 Cleft lip with or without cleft palate; LIHC cis rs943466 1.000 rs943462 chr6:33769578 G/A cg25922239 chr6:33757077 LEMD2 -0.5 -6.41 -0.33 4.91e-10 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs1580019 0.713 rs2122632 chr7:32524686 A/G cg14728415 chr7:32535168 LSM5;AVL9 -0.42 -6.13 -0.31 2.42e-9 Cognitive ability; LIHC cis rs2274273 1.000 rs7160110 chr14:55594635 A/G cg01864836 chr14:55583639 NA -0.37 -6.68 -0.34 9.57e-11 Protein biomarker; LIHC cis rs6762 0.748 rs7936838 chr11:839093 G/C cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.39 -0.45 8.43e-19 Mean platelet volume; LIHC cis rs597539 0.518 rs35093305 chr11:68730729 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 9.85 0.47 2.57e-20 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs3812111 0.774 rs564980 chr6:116424653 C/T cg08036074 chr6:116424633 NT5DC1 0.66 12.08 0.55 3.11e-28 Age-related macular degeneration; LIHC cis rs2280630 0.505 rs2249736 chr3:39195462 G/T cg02254461 chr3:39195904 CSRNP1 -0.32 -5.89 -0.3 9.24e-9 Verbal declarative memory; LIHC cis rs116095464 0.558 rs10057674 chr5:266813 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.4 0.45 8.18e-19 Platelet count; LIHC cis rs1348850 0.519 rs13034781 chr2:178523550 C/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.09 0.4 1.05e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9308433 0.529 rs9430133 chr1:214496313 C/T cg06198575 chr1:214491504 SMYD2 0.56 5.92 0.3 7.86e-9 IgG glycosylation; LIHC cis rs787274 1.000 rs787274 chr9:115550363 A/C cg13803584 chr9:115635662 SNX30 -0.59 -6.39 -0.33 5.54e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1775715 0.513 rs2808089 chr10:32145112 A/T cg14930904 chr10:32216787 ARHGAP12 0.35 5.99 0.31 5.46e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs950776 0.507 rs12912673 chr15:78810216 T/C cg06917634 chr15:78832804 PSMA4 0.9 13.21 0.58 1.73e-32 Sudden cardiac arrest; LIHC cis rs17428076 0.831 rs55957712 chr2:172587956 C/T cg13550731 chr2:172543902 DYNC1I2 0.38 6.21 0.32 1.54e-9 Myopia; LIHC cis rs56235845 0.694 rs11738681 chr5:176761535 A/G cg17509989 chr5:176798049 RGS14 0.58 7.45 0.37 7.88e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs10065203 0.527 rs152177 chr5:14354270 G/A cg26595256 chr5:14380529 TRIO -0.43 -6.46 -0.33 3.55e-10 Paclitaxel-induced neuropathy; LIHC cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.97 12.39 0.56 2.21e-29 Alzheimer's disease; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg13580526 chr8:37553077 ZNF703 -0.45 -6.24 -0.32 1.32e-9 Bilirubin levels; LIHC cis rs34779708 0.931 rs13377158 chr10:35370465 A/C cg03585969 chr10:35415529 CREM -0.85 -12.9 -0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17685 0.725 rs2302436 chr7:75676988 A/T cg16489192 chr7:75678113 MDH2;STYXL1 0.38 6.09 0.31 2.99e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg04013166 chr16:89971882 TCF25 -0.64 -9.3 -0.45 1.7e-18 Skin colour saturation; LIHC cis rs2073300 0.609 rs77908916 chr20:23405626 C/G cg16736954 chr20:23401023 NAPB 0.72 8.46 0.42 7.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs12744310 0.887 rs2363810 chr1:41783873 C/T cg03962019 chr1:41807865 NA 0.38 6.12 0.31 2.59e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1707322 1.000 rs4539075 chr1:46358010 C/T cg03146154 chr1:46216737 IPP 0.47 7.72 0.39 1.3e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10744422 0.925 rs2061098 chr12:123349410 T/C cg25930673 chr12:123319894 HIP1R -0.81 -9.36 -0.45 1.08e-18 Schizophrenia; LIHC cis rs1707322 1.000 rs1707322 chr1:46505147 C/T cg03146154 chr1:46216737 IPP 0.45 7.36 0.37 1.36e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs801193 0.569 rs7782587 chr7:66166472 C/T cg18876405 chr7:65276391 NA 0.33 5.97 0.31 6.1e-9 Aortic root size; LIHC cis rs7520050 0.933 rs4504835 chr1:46455571 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.42 6.12 0.31 2.58e-9 Red blood cell count;Reticulocyte count; LIHC trans rs6906287 0.625 rs9320649 chr6:118693665 A/G cg05523500 chr3:73046033 PPP4R2 0.35 6.11 0.31 2.74e-9 Electrocardiographic conduction measures; LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs911119 0.908 rs6048950 chr20:23603252 A/G cg16589663 chr20:23618590 CST3 0.75 7.89 0.39 4.1e-14 Chronic kidney disease; LIHC cis rs11958404 0.517 rs17680818 chr5:157248548 T/A cg05962755 chr5:157440814 NA 0.67 6.76 0.34 5.96e-11 IgG glycosylation; LIHC cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg06558623 chr16:89946397 TCF25 0.94 14.48 0.62 2.22e-37 Skin colour saturation; LIHC cis rs10751667 0.666 rs6597962 chr11:976351 C/T cg06064525 chr11:970664 AP2A2 -0.56 -14.9 -0.63 4.72e-39 Alzheimer's disease (late onset); LIHC cis rs9811920 0.609 rs6809988 chr3:99656615 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.19 0.36 4.19e-12 Axial length; LIHC cis rs35110281 0.748 rs162403 chr21:44963365 C/G cg01579765 chr21:45077557 HSF2BP -0.33 -6.05 -0.31 3.85e-9 Mean corpuscular volume; LIHC cis rs9381040 0.655 rs2268194 chr6:41024447 T/C cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.13 -0.31 2.41e-9 Alzheimer's disease (late onset); LIHC cis rs7319311 1.000 rs7320755 chr13:111031092 C/G cg05272587 chr13:111038400 COL4A2 -0.36 -7.5 -0.38 5.7e-13 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.61 0.38 2.72e-13 Prudent dietary pattern; LIHC cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg12310025 chr6:25882481 NA 0.5 6.2 0.32 1.63e-9 Intelligence (multi-trait analysis); LIHC cis rs8013055 0.846 rs10139300 chr14:105974501 A/G cg19700328 chr14:106028568 NA -0.35 -7.61 -0.38 2.64e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC trans rs1814175 0.935 rs10839317 chr11:49657228 A/C cg03929089 chr4:120376271 NA -0.89 -17.53 -0.69 1.56e-49 Height; LIHC trans rs1814175 0.559 rs1818892 chr11:49863084 C/A cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.43e-11 Height; LIHC cis rs2354432 0.607 rs894469 chr1:146672906 C/T cg25205988 chr1:146714368 CHD1L 0.87 5.97 0.31 6.1e-9 Mitochondrial DNA levels; LIHC cis rs8062405 1.000 rs62037369 chr16:28883841 C/T cg16576597 chr16:28551801 NUPR1 0.37 5.83 0.3 1.26e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs7618501 0.633 rs6446189 chr3:50008566 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.44 0.45 5.75e-19 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.888 rs11794648 chr9:111829792 C/T cg05043794 chr9:111880884 C9orf5 -0.26 -5.95 -0.31 6.67e-9 Menarche (age at onset); LIHC cis rs9291683 0.551 rs2240720 chr4:10020480 C/T cg11266682 chr4:10021025 SLC2A9 0.32 6.87 0.35 3.13e-11 Bone mineral density; LIHC cis rs9399135 0.660 rs4267967 chr6:135272477 T/G cg22676075 chr6:135203613 NA 0.41 6.5 0.33 2.9e-10 Red blood cell count; LIHC cis rs2370759 1.000 rs16933243 chr10:32615135 T/C cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs1552244 0.882 rs13089863 chr3:10032259 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 0.62 9.15 0.44 5.21e-18 Alzheimer's disease; LIHC cis rs9309711 0.643 rs4535074 chr2:3481637 A/G cg10845886 chr2:3471009 TTC15 -0.43 -8.22 -0.41 4.4e-15 Neurofibrillary tangles; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg20831041 chr11:464554 PTDSS2 0.44 6.67 0.34 1.06e-10 Bilirubin levels; LIHC cis rs2932538 0.845 rs6682678 chr1:113206920 A/G cg22162597 chr1:113214053 CAPZA1 -0.73 -10.96 -0.51 3.67e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg03452623 chr4:187889614 NA -0.32 -8.25 -0.41 3.55e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs11122272 0.614 rs78172021 chr1:231525160 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs243505 0.732 rs10255478 chr7:148501985 C/G cg09806900 chr7:148480153 CUL1 0.44 6.52 0.33 2.48e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2762353 0.505 rs2096386 chr6:25787817 C/T cg03264133 chr6:25882463 NA 0.41 6.02 0.31 4.51e-9 Blood metabolite levels; LIHC cis rs1564271 0.506 rs1148163 chr10:26929671 G/C cg13837822 chr10:26931731 LOC731789 0.43 8.11 0.4 8.99e-15 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs10170846 0.861 rs6740452 chr2:223518452 C/T cg25565276 chr2:223520875 FARSB 0.63 9.32 0.45 1.52e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg09367891 chr1:107599246 PRMT6 0.66 10.9 0.51 6.27e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs748404 0.697 rs1814323 chr15:43563237 T/C cg27015174 chr15:43622946 ADAL;LCMT2 -0.46 -7.9 -0.39 3.82e-14 Lung cancer; LIHC cis rs12477438 0.798 rs1993230 chr2:99686079 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.87 -0.51 7.74e-24 Chronic sinus infection; LIHC cis rs7937890 0.904 rs11023169 chr11:14290985 C/A cg06199346 chr11:14280333 SPON1 0.34 5.76 0.3 1.85e-8 Mitochondrial DNA levels; LIHC cis rs7772486 0.790 rs2247429 chr6:146217769 T/C cg05347473 chr6:146136440 FBXO30 0.38 6.04 0.31 4.02e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg07061783 chr6:25882402 NA -0.5 -6.41 -0.33 4.71e-10 Intelligence (multi-trait analysis); LIHC cis rs7027203 0.828 rs4743934 chr9:96581893 A/G cg13679303 chr9:96623674 NA -0.3 -6.73 -0.34 7.39e-11 DNA methylation (variation); LIHC cis rs7635838 0.892 rs9310384 chr3:11491980 A/G cg00170343 chr3:11313890 ATG7 0.42 6.7 0.34 8.68e-11 HDL cholesterol; LIHC cis rs8180040 0.701 rs7625067 chr3:47095305 T/C cg02527881 chr3:46936655 PTH1R -0.31 -6.14 -0.32 2.24e-9 Colorectal cancer; LIHC cis rs7216064 1.000 rs62084214 chr17:65843325 C/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.38 -0.45 9.54e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2204008 0.869 rs34438288 chr12:38211582 G/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC trans rs116095464 0.558 rs7715108 chr5:264661 A/G cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs68170813 0.559 rs11773514 chr7:106958469 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.88 -0.3 9.71e-9 Coronary artery disease; LIHC cis rs7659604 0.539 rs1507995 chr4:122748308 G/A cg19748678 chr4:122722346 EXOSC9 0.67 11.2 0.52 4.97e-25 Type 2 diabetes; LIHC cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.52 0.49 1.28e-22 Total body bone mineral density; LIHC cis rs1400745 0.718 rs799681 chr14:35350579 A/G cg05294307 chr14:35346193 BAZ1A -0.45 -7.45 -0.37 7.57e-13 Monocyte count; LIHC cis rs950169 0.922 rs62028133 chr15:84919375 A/C cg03959625 chr15:84868606 LOC388152 0.46 6.65 0.34 1.14e-10 Schizophrenia; LIHC cis rs7659604 0.628 rs3828485 chr4:122722368 G/A cg20573242 chr4:122745356 CCNA2 0.54 7.85 0.39 5.47e-14 Type 2 diabetes; LIHC trans rs911555 0.755 rs55742283 chr14:103942965 A/G cg17675199 chr6:35436792 RPL10A -0.44 -9.19 -0.45 3.88e-18 Intelligence (multi-trait analysis); LIHC trans rs2243480 0.708 rs781141 chr7:65438553 A/G cg10756647 chr7:56101905 PSPH 1.1 13.62 0.59 4.65e-34 Diabetic kidney disease; LIHC cis rs7666738 0.830 rs7667796 chr4:99071415 G/T cg05340658 chr4:99064831 C4orf37 -0.7 -13.03 -0.58 8.42e-32 Colonoscopy-negative controls vs population controls; LIHC cis rs6701037 0.512 rs4650716 chr1:175128711 C/A cg00958927 chr1:175162553 KIAA0040 0.39 6.75 0.34 6.39e-11 Alcohol dependence; LIHC cis rs11122272 0.735 rs2808604 chr1:231538916 T/C cg06096015 chr1:231504339 EGLN1 0.49 9.07 0.44 9.82e-18 Hemoglobin concentration; LIHC cis rs3780378 1.000 rs3780378 chr9:5112288 C/T cg02405213 chr9:5042618 JAK2 -0.43 -7.54 -0.38 4.15e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs11971779 0.680 rs10242419 chr7:139089380 A/G cg07862535 chr7:139043722 LUC7L2 -0.58 -10.06 -0.48 5.01e-21 Diisocyanate-induced asthma; LIHC cis rs801193 1.000 rs10252765 chr7:66228732 C/G cg18876405 chr7:65276391 NA 0.41 7.06 0.36 9.05e-12 Aortic root size; LIHC cis rs8062405 0.755 rs4787456 chr16:28559573 C/T cg16576597 chr16:28551801 NUPR1 0.49 7.76 0.39 9.79e-14 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2228479 0.850 rs11076623 chr16:89844120 G/T cg04013166 chr16:89971882 TCF25 0.5 6.13 0.31 2.39e-9 Skin colour saturation; LIHC cis rs941873 0.868 rs2145998 chr10:81121696 T/A cg09469691 chr10:81107165 PPIF 0.67 10.26 0.49 1e-21 Height; LIHC cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg10150615 chr22:24372951 LOC391322 -0.63 -9.39 -0.45 8.72e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7917772 0.503 rs6584510 chr10:104299868 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg11279151 chr3:101281821 RG9MTD1 -0.4 -6.08 -0.31 3.28e-9 Colorectal cancer; LIHC cis rs2204008 0.597 rs4002591 chr12:38133841 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.8 0.3 1.53e-8 Bladder cancer; LIHC cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.15 0.44 5.14e-18 Bipolar disorder; LIHC cis rs6570726 1.000 rs450076 chr6:145847655 G/T cg23711669 chr6:146136114 FBXO30 0.54 9.77 0.47 4.95e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7116495 1.000 rs73543633 chr11:71828844 T/C cg26138937 chr11:71823887 C11orf51 0.82 8.33 0.41 2.03e-15 Severe influenza A (H1N1) infection; LIHC cis rs7944735 0.568 rs59631865 chr11:47501619 T/G cg20307385 chr11:47447363 PSMC3 -0.56 -6.36 -0.33 6.34e-10 Intraocular pressure; LIHC cis rs3540 0.512 rs8033595 chr15:91083353 G/A cg22089800 chr15:90895588 ZNF774 -0.5 -7.26 -0.37 2.6e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs10751667 1.000 rs10902246 chr11:953674 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.33 0.52 1.77e-25 Alzheimer's disease (late onset); LIHC cis rs11098499 0.954 rs34858317 chr4:120387110 A/C cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs9649213 0.593 rs736754 chr7:97931559 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.82e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg11301795 chr4:187892539 NA -0.27 -7.13 -0.36 6.08e-12 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.754 rs2036860 chr4:120248934 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.27 0.41 3.06e-15 Corneal astigmatism; LIHC cis rs7605378 0.528 rs7592587 chr2:200786516 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.51 6.69 0.34 9.09e-11 Osteoporosis; LIHC cis rs11229555 0.645 rs36019763 chr11:58232283 G/T cg15696309 chr11:58395628 NA -0.64 -7.36 -0.37 1.38e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs8177253 1.000 rs8177271 chr3:133482230 G/A cg12373951 chr3:133503437 NA 0.69 12.26 0.55 6.81e-29 Iron status biomarkers; LIHC cis rs2439831 1.000 rs2251538 chr15:43767209 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.59 0.59 6.27e-34 Lung cancer in ever smokers; LIHC cis rs7772486 0.790 rs7753092 chr6:146248863 C/T cg05347473 chr6:146136440 FBXO30 -0.37 -5.86 -0.3 1.07e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs801193 1.000 rs1553610 chr7:66197233 T/C cg18876405 chr7:65276391 NA 0.42 7.29 0.37 2.17e-12 Aortic root size; LIHC cis rs7582180 0.629 rs11123827 chr2:100951248 C/G cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.91e-16 Intelligence (multi-trait analysis); LIHC cis rs7587476 0.784 rs13026390 chr2:215687075 C/T cg04530015 chr2:215796436 ABCA12 0.39 6.34 0.32 7.23e-10 Neuroblastoma; LIHC cis rs12477438 0.501 rs13008171 chr2:99743419 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs2346177 0.844 rs34712412 chr2:46652428 G/A cg02822958 chr2:46747628 ATP6V1E2 0.39 6.06 0.31 3.57e-9 HDL cholesterol; LIHC cis rs7216064 1.000 rs62084213 chr17:65842016 A/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.38 -0.45 9.54e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs875971 1.000 rs778699 chr7:65868290 G/A cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs801193 1.000 rs2707850 chr7:66203870 G/T cg11764359 chr7:65958608 NA 0.71 10.58 0.5 8.11e-23 Aortic root size; LIHC cis rs35306767 0.668 rs12784928 chr10:1083617 A/C cg26597838 chr10:835615 NA 0.57 6.4 0.33 5.1e-10 Eosinophil percentage of granulocytes; LIHC cis rs8060686 0.516 rs7206792 chr16:68168200 C/G cg05110241 chr16:68378359 PRMT7 -0.53 -6.21 -0.32 1.5e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs57502260 0.915 rs7106320 chr11:68210118 C/T cg16797656 chr11:68205561 LRP5 0.62 8.35 0.41 1.75e-15 Total body bone mineral density (age 45-60); LIHC cis rs6120849 0.754 rs6120788 chr20:33583716 C/T cg24642439 chr20:33292090 TP53INP2 0.65 7.15 0.36 5.41e-12 Protein C levels; LIHC cis rs9921222 0.692 rs11860497 chr16:405416 A/G cg00101154 chr16:420108 MRPL28 -0.47 -7.24 -0.36 2.93e-12 Bone mineral density (spine);Bone mineral density; LIHC cis rs3857067 0.806 rs72665629 chr4:95112160 T/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs921968 0.541 rs41461846 chr2:219313354 A/G cg02176678 chr2:219576539 TTLL4 -0.58 -8.1 -0.4 9.53e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs55665837 1.000 rs10832257 chr11:14443316 A/G cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs782590 0.967 rs35504023 chr2:55806503 C/T cg18811423 chr2:55921094 PNPT1 -0.89 -14.18 -0.61 3.26e-36 Metabolic syndrome; LIHC cis rs7395581 0.877 rs10838690 chr11:47335075 A/G cg26139080 chr11:47293733 MADD -0.5 -8.45 -0.42 8.46e-16 HDL cholesterol; LIHC cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg11764359 chr7:65958608 NA 0.68 9.31 0.45 1.58e-18 Calcium levels; LIHC cis rs798554 0.797 rs798497 chr7:2795957 A/G cg19346786 chr7:2764209 NA -0.46 -7.08 -0.36 8.21e-12 Height; LIHC cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg21724239 chr8:58056113 NA 0.55 6.84 0.35 3.77e-11 Developmental language disorder (linguistic errors); LIHC cis rs561341 1.000 rs55736640 chr17:30333848 G/A cg00745463 chr17:30367425 LRRC37B -0.8 -5.79 -0.3 1.57e-8 Hip circumference adjusted for BMI; LIHC cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg06108461 chr20:60628389 TAF4 -1.0 -17.47 -0.69 2.63e-49 Body mass index; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC cis rs11676348 0.935 rs4674248 chr2:218960131 T/C cg00012203 chr2:219082015 ARPC2 -0.54 -7.18 -0.36 4.33e-12 Ulcerative colitis; LIHC cis rs7044106 0.762 rs1470307 chr9:123433039 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.79 0.39 8.18e-14 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg08280861 chr8:58055591 NA 0.49 6.11 0.31 2.69e-9 Developmental language disorder (linguistic errors); LIHC cis rs600806 0.778 rs2140923 chr1:110004990 C/T cg11161837 chr1:110010384 SYPL2 0.46 6.18 0.32 1.81e-9 Intelligence (multi-trait analysis); LIHC cis rs1451375 0.959 rs1451373 chr7:50622606 A/G cg14593290 chr7:50529359 DDC 0.4 6.65 0.34 1.15e-10 Malaria; LIHC cis rs922107 0.713 rs2031119 chr1:90042745 C/T cg15422784 chr1:90023713 LRRC8B -0.46 -7.54 -0.38 4.16e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs2228479 0.850 rs1800339 chr16:89839637 C/A cg19635926 chr16:89946313 TCF25 0.49 6.38 0.33 5.81e-10 Skin colour saturation; LIHC cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg19318889 chr4:1322082 MAEA 0.57 9.02 0.44 1.4e-17 Longevity; LIHC cis rs12980942 0.935 rs16958996 chr19:41825138 C/T cg25627403 chr19:41769009 HNRNPUL1 0.48 5.99 0.31 5.29e-9 Coronary artery disease; LIHC cis rs8141529 0.748 rs7287918 chr22:29281710 G/A cg15103426 chr22:29168792 CCDC117 0.57 9.3 0.45 1.74e-18 Lymphocyte counts; LIHC cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg07424592 chr7:64974309 NA -0.8 -9.27 -0.45 2.17e-18 Diabetic kidney disease; LIHC cis rs4788570 0.686 rs9937511 chr16:71815913 C/T cg06353428 chr16:71660113 MARVELD3 1.3 13.62 0.59 4.58e-34 Intelligence (multi-trait analysis); LIHC cis rs600806 0.751 rs1933182 chr1:109999838 A/C cg11161837 chr1:110010384 SYPL2 0.44 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis); LIHC cis rs1144333 0.655 rs3765682 chr1:76333172 T/C cg22875332 chr1:76189707 ACADM 0.44 6.44 0.33 4.14e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs12022452 0.591 rs11208315 chr1:40985402 G/C cg25568243 chr1:40974465 DEM1 0.46 6.17 0.32 1.91e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg07167872 chr1:205819463 PM20D1 0.6 8.79 0.43 7.43e-17 Menarche (age at onset); LIHC cis rs6570726 0.935 rs428659 chr6:145827039 T/C cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs10197940 0.686 rs12616688 chr2:152242099 C/G cg19508488 chr2:152266495 RIF1 0.52 7.32 0.37 1.84e-12 Lung cancer; LIHC cis rs7000551 0.689 rs12545909 chr8:22310052 A/G cg12081754 chr8:22256438 SLC39A14 -0.52 -8.5 -0.42 5.81e-16 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs77633900 0.772 rs283802 chr15:76791270 C/T cg21673338 chr15:77095150 SCAPER -0.51 -5.84 -0.3 1.21e-8 Non-glioblastoma glioma;Glioma; LIHC cis rs477692 0.699 rs557311 chr10:131389484 A/G cg05714579 chr10:131428358 MGMT 0.43 7.1 0.36 7.32e-12 Response to temozolomide; LIHC cis rs10464366 0.746 rs6945547 chr7:39145389 C/G cg21665744 chr7:39171113 POU6F2 0.31 5.78 0.3 1.7e-8 IgG glycosylation; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg07308232 chr7:1071921 C7orf50 -0.36 -5.81 -0.3 1.43e-8 Longevity;Endometriosis; LIHC cis rs3736485 0.966 rs4775959 chr15:51891636 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.66e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg11011602 chr9:136215029 SNORD24;MED22;RPL7A -0.44 -6.86 -0.35 3.22e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11971779 0.648 rs6947309 chr7:139035830 C/T cg07862535 chr7:139043722 LUC7L2 0.61 10.49 0.49 1.66e-22 Diisocyanate-induced asthma; LIHC cis rs1577917 0.958 rs12192546 chr6:86476484 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.48 7.71 0.38 1.42e-13 Response to antipsychotic treatment; LIHC cis rs2204008 0.720 rs10880697 chr12:38594529 G/C cg26384229 chr12:38710491 ALG10B 0.87 10.03 0.48 6.16e-21 Bladder cancer; LIHC cis rs10089 1.000 rs10478798 chr5:127442394 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.03e-11 Ileal carcinoids; LIHC cis rs763121 0.853 rs6001182 chr22:39047443 A/G cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs9905704 0.671 rs28709536 chr17:57008912 C/A cg12560992 chr17:57184187 TRIM37 0.68 10.02 0.48 7e-21 Testicular germ cell tumor; LIHC cis rs8072100 0.967 rs4289035 chr17:45707211 C/T cg08085267 chr17:45401833 C17orf57 -0.4 -6.04 -0.31 4.06e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs36051895 0.632 rs62541916 chr9:5151904 C/A cg02405213 chr9:5042618 JAK2 -0.68 -12.43 -0.56 1.61e-29 Pediatric autoimmune diseases; LIHC cis rs6942756 0.806 rs1880854 chr7:128949748 G/T cg02491457 chr7:128862824 NA 0.6 9.45 0.46 5.52e-19 White matter hyperintensity burden; LIHC cis rs2268241 0.877 rs17885509 chr21:34779630 C/T cg14850771 chr21:34775459 IFNGR2 0.91 13.85 0.6 6.07e-35 Obesity-related traits; LIHC cis rs1434579 0.966 rs1062093 chr19:44931995 C/G cg15540054 chr19:45004280 ZNF180 0.58 7.98 0.4 2.25e-14 Tuberculosis; LIHC cis rs11252926 0.931 rs12358336 chr10:566981 A/T cg16346588 chr10:242978 ZMYND11 -0.47 -5.82 -0.3 1.35e-8 Psychosis in Alzheimer's disease; LIHC cis rs5769765 0.657 rs8136116 chr22:50256886 T/A cg02269571 chr22:50332266 NA 0.7 8.05 0.4 1.38e-14 Schizophrenia; LIHC cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg03264133 chr6:25882463 NA -0.62 -7.66 -0.38 2e-13 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00462763 chr11:64949223 CAPN1 0.45 6.22 0.32 1.45e-9 Lung function (FEV1/FVC); LIHC cis rs921968 0.565 rs3821035 chr2:219620223 T/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs12620999 0.941 rs10929215 chr2:238037456 G/A cg15676719 chr1:167598521 RCSD1 -0.37 -6.65 -0.34 1.18e-10 Systemic lupus erythematosus; LIHC cis rs6430585 0.528 rs75753154 chr2:136665711 T/C cg07169764 chr2:136633963 MCM6 1.28 22.06 0.77 1.09e-67 Corneal structure; LIHC cis rs1577917 0.559 rs1173418 chr6:86402916 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.36 0.33 6.34e-10 Response to antipsychotic treatment; LIHC cis rs7552404 0.731 rs10732723 chr1:76392437 C/T cg10523679 chr1:76189770 ACADM -0.57 -6.86 -0.35 3.23e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.71 -12.61 -0.56 3.32e-30 Prudent dietary pattern; LIHC cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg10360323 chr17:41437877 NA 0.41 6.1 0.31 2.81e-9 Menopause (age at onset); LIHC cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg12379764 chr21:47803548 PCNT -0.65 -9.89 -0.47 1.94e-20 Testicular germ cell tumor; LIHC cis rs763121 0.819 rs5757160 chr22:38989646 T/C cg14440974 chr22:39074834 NA -0.36 -5.97 -0.31 5.9e-9 Menopause (age at onset); LIHC cis rs11958404 0.929 rs79656592 chr5:157430291 G/A cg05962755 chr5:157440814 NA 1.04 11.66 0.53 1.09e-26 IgG glycosylation; LIHC cis rs8062405 1.000 rs62037367 chr16:28874547 C/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs796364 0.906 rs281789 chr2:200780698 T/G cg23649088 chr2:200775458 C2orf69 0.49 5.96 0.31 6.29e-9 Schizophrenia; LIHC cis rs9911578 0.813 rs12452313 chr17:57129882 C/A cg12560992 chr17:57184187 TRIM37 -0.86 -13.85 -0.6 6.32e-35 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.866 rs56331709 chr3:40356558 A/C cg09455208 chr3:40491958 NA 0.33 6.21 0.32 1.5e-9 Renal cell carcinoma; LIHC trans rs2270927 0.510 rs2972840 chr5:75572956 G/A cg13563193 chr19:33072644 PDCD5 0.84 8.0 0.4 1.89e-14 Mean corpuscular volume; LIHC cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg18404041 chr3:52824283 ITIH1 -0.58 -9.37 -0.45 1.02e-18 Bipolar disorder; LIHC cis rs9902453 0.838 rs9646438 chr17:28209091 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 11.04 0.51 1.98e-24 Coffee consumption (cups per day); LIHC cis rs1949733 0.523 rs4619877 chr4:8543235 G/A cg11789530 chr4:8429930 ACOX3 -0.59 -8.17 -0.4 6.22e-15 Response to antineoplastic agents; LIHC cis rs35883536 0.846 rs964905 chr1:101087131 T/C cg14515779 chr1:101123966 NA 0.63 11.26 0.52 3.12e-25 Monocyte count; LIHC cis rs7914558 0.646 rs7100709 chr10:104649729 A/C cg15744005 chr10:104629667 AS3MT -0.36 -7.58 -0.38 3.35e-13 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs225245 0.755 rs6505491 chr17:34026335 A/G cg05299278 chr17:33885742 SLFN14 0.23 6.2 0.32 1.65e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs11758351 1.000 rs112751982 chr6:26191958 C/T cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC cis rs3749237 0.595 rs11130196 chr3:49490149 A/C cg03060546 chr3:49711283 APEH 0.6 9.97 0.47 9.89e-21 Resting heart rate; LIHC cis rs796364 0.760 rs55906940 chr2:201049386 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.73 -0.34 7.3e-11 Schizophrenia; LIHC cis rs7845219 0.544 rs2123647 chr8:95931782 A/G cg13393036 chr8:95962371 TP53INP1 0.31 5.97 0.31 5.81e-9 Type 2 diabetes; LIHC cis rs9399135 0.967 rs9376085 chr6:135371224 T/C cg22676075 chr6:135203613 NA 0.4 6.36 0.33 6.58e-10 Red blood cell count; LIHC cis rs12824058 0.737 rs2398508 chr12:130816460 G/A cg24838063 chr12:130822603 PIWIL1 0.66 9.47 0.46 4.81e-19 Menopause (age at onset); LIHC cis rs8049040 0.609 rs4258624 chr16:71467951 C/T cg06353428 chr16:71660113 MARVELD3 0.61 6.69 0.34 9.08e-11 Blood protein levels; LIHC cis rs7551222 0.749 rs4951409 chr1:204560990 A/T cg20240347 chr1:204465584 NA -0.3 -6.06 -0.31 3.55e-9 Schizophrenia; LIHC cis rs992157 0.687 rs10206984 chr2:219066980 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.79 13.25 0.58 1.22e-32 Colorectal cancer; LIHC cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 10.44 0.49 2.42e-22 Platelet count; LIHC cis rs1144333 1.000 rs1021464 chr1:76375415 G/A cg22875332 chr1:76189707 ACADM 0.4 6.27 0.32 1.07e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs8044995 0.563 rs73615919 chr16:68398862 C/T cg09835421 chr16:68378352 PRMT7 -0.8 -9.67 -0.46 1.03e-19 Schizophrenia; LIHC cis rs2439831 0.681 rs524527 chr15:43599116 C/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.76 -11.22 -0.52 4.49e-25 Lung cancer in ever smokers; LIHC cis rs2412488 1.000 rs2271554 chr4:54252222 C/G cg22241045 chr4:54363911 LNX1 -0.46 -7.29 -0.37 2.2e-12 DNA methylation (variation); LIHC cis rs1008375 0.966 rs1476836 chr4:17585014 G/C cg16339924 chr4:17578868 LAP3 0.46 6.27 0.32 1.09e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg21448741 chr8:58168803 NA 0.37 6.69 0.34 9.34e-11 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19371097 chr1:17735001 RCC2 0.42 6.18 0.32 1.79e-9 Pancreatic cancer; LIHC cis rs1348850 0.831 rs1345139 chr2:178449791 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.14 0.52 8.53e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6840360 1.000 rs10023298 chr4:152666768 A/C cg22705602 chr4:152727874 NA -0.34 -7.17 -0.36 4.61e-12 Intelligence (multi-trait analysis); LIHC cis rs6933660 0.800 rs13201167 chr6:151773504 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.58 -8.85 -0.43 4.95e-17 Menarche (age at onset); LIHC cis rs10768122 0.642 rs11033079 chr11:35362050 G/T cg13971030 chr11:35366721 SLC1A2 -0.36 -5.91 -0.3 8.45e-9 Vitiligo; LIHC cis rs6502050 0.698 rs6502076 chr17:80121978 A/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs344364 0.511 rs337286 chr16:1965719 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.62 -7.59 -0.38 3.13e-13 Glomerular filtration rate in chronic kidney disease; LIHC trans rs9914544 0.545 rs12937933 chr17:18770283 C/G cg21372672 chr17:16614065 CCDC144A -0.28 -6.73 -0.34 7.38e-11 Educational attainment (years of education); LIHC cis rs7666738 0.546 rs6827131 chr4:98744810 C/G cg05340658 chr4:99064831 C4orf37 0.49 6.3 0.32 9.41e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs2130392 0.503 rs2871418 chr4:185654723 A/G cg21366198 chr4:185655624 MLF1IP 0.62 10.16 0.48 2.23e-21 Kawasaki disease; LIHC trans rs2727020 0.894 rs10839265 chr11:49369733 C/T cg18944383 chr4:111397179 ENPEP 0.28 6.52 0.33 2.56e-10 Coronary artery disease; LIHC cis rs7412746 0.611 rs111842513 chr1:150712926 G/A cg18016565 chr1:150552671 MCL1 0.58 11.27 0.52 2.87e-25 Melanoma; LIHC trans rs11157436 0.918 rs12433895 chr14:22622510 A/G cg13567813 chr19:50879636 NR1H2 0.42 6.05 0.31 3.84e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs7917772 0.582 rs4408249 chr10:104374653 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.85 0.39 5.44e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1775715 0.707 rs2778669 chr10:32161541 C/T cg14930904 chr10:32216787 ARHGAP12 0.35 6.1 0.31 2.93e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs919433 0.648 rs787975 chr2:198248128 C/T cg03934865 chr2:198174659 NA 0.54 8.22 0.41 4.19e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs1577917 1.000 rs4706254 chr6:86602813 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.41 -7.67 -0.38 1.82e-13 Response to antipsychotic treatment; LIHC cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg06481639 chr22:41940642 POLR3H 0.61 5.85 0.3 1.16e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg11766577 chr21:47581405 C21orf56 -0.37 -5.86 -0.3 1.1e-8 Testicular germ cell tumor; LIHC cis rs12586317 0.620 rs17103042 chr14:35575428 T/C cg16230307 chr14:35515116 FAM177A1 0.79 13.26 0.58 1.1e-32 Psoriasis; LIHC cis rs8084351 0.501 rs28629395 chr18:50604504 G/A cg24270629 chr18:50823537 DCC 0.46 7.05 0.36 9.72e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs1707322 1.000 rs11211232 chr1:46411146 C/T cg06784218 chr1:46089804 CCDC17 0.38 6.89 0.35 2.69e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 0.688 rs113940455 chr3:10014165 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.75 10.06 0.48 5e-21 Alzheimer's disease; LIHC cis rs6089584 1.000 rs6089581 chr20:60562394 G/A cg23262073 chr20:60523788 NA -0.28 -5.86 -0.3 1.09e-8 Body mass index; LIHC cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 4.98e-16 Developmental language disorder (linguistic errors); LIHC cis rs2637266 1.000 rs2395389 chr10:78357701 C/T cg18941641 chr10:78392320 NA 0.28 5.88 0.3 9.74e-9 Pulmonary function; LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg23131131 chr22:24373011 LOC391322 -0.64 -9.15 -0.44 5.16e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3818285 0.544 rs7899805 chr10:111671177 G/A cg00817464 chr10:111662876 XPNPEP1 -0.53 -8.36 -0.41 1.61e-15 Superior crus of antihelix expression; LIHC cis rs3814244 0.528 rs2860609 chr12:68390995 A/G cg15249341 chr12:68405565 NA 0.34 6.87 0.35 2.97e-11 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg21280719 chr6:42927975 GNMT -0.32 -7.23 -0.36 3.28e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs17685 0.736 rs4732594 chr7:75753273 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs736408 0.716 rs2300149 chr3:52822921 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.14 0.36 5.48e-12 Bipolar disorder; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC cis rs10489202 0.632 rs413168 chr1:168005789 C/G cg24449463 chr1:168025552 DCAF6 -0.64 -9.94 -0.47 1.26e-20 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03952484 chr1:149899818 SF3B4 0.51 8.05 0.4 1.34e-14 Pancreatic cancer; LIHC cis rs611744 0.967 rs859788 chr8:109227570 A/G cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04413644 chr1:9242184 NA 0.44 6.3 0.32 9.03e-10 Lung function (FEV1/FVC); LIHC cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg18404041 chr3:52824283 ITIH1 -0.58 -9.69 -0.46 8.58e-20 Bipolar disorder; LIHC cis rs3806843 0.966 rs10053945 chr5:140160127 C/T cg19875535 chr5:140030758 IK 0.36 5.95 0.31 6.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg05564831 chr3:52568323 NT5DC2 0.36 5.86 0.3 1.11e-8 Bipolar disorder; LIHC cis rs2455799 0.634 rs13085226 chr3:15923750 C/T cg12698662 chr3:15914712 MIR563 -0.39 -7.36 -0.37 1.42e-12 Mean platelet volume; LIHC cis rs921968 0.643 rs579610 chr2:219327582 C/A cg02985541 chr2:219472218 PLCD4 0.46 8.93 0.43 2.66e-17 Mean corpuscular hemoglobin concentration; LIHC cis rs7107174 1.000 rs2512549 chr11:77940163 A/G cg02023728 chr11:77925099 USP35 -0.44 -8.57 -0.42 3.49e-16 Testicular germ cell tumor; LIHC cis rs4808199 0.895 rs4808194 chr19:19435680 T/G cg03709012 chr19:19516395 GATAD2A 0.97 15.52 0.64 1.64e-41 Nonalcoholic fatty liver disease; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg10755058 chr3:40428713 ENTPD3 0.41 6.99 0.35 1.47e-11 Renal cell carcinoma; LIHC cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11588001 chr19:29704240 UQCRFS1 0.41 6.53 0.33 2.4e-10 Lung function (FEV1/FVC); LIHC cis rs7552404 1.000 rs7516226 chr1:76234257 G/A cg03433033 chr1:76189801 ACADM 0.68 9.31 0.45 1.54e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2033732 0.706 rs7839360 chr8:85069719 G/T cg05716166 chr8:85095498 RALYL 0.38 6.03 0.31 4.24e-9 Body mass index; LIHC cis rs12477438 0.520 rs10865029 chr2:99718298 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.05 0.6 1.02e-35 Chronic sinus infection; LIHC cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg05185784 chr16:90016020 DEF8 -0.46 -5.95 -0.31 6.75e-9 Skin colour saturation; LIHC cis rs427394 0.593 rs880993 chr5:6732120 C/G cg10857441 chr5:6722123 POLS -0.38 -6.45 -0.33 3.89e-10 Menopause (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20279895 chr14:31091012 SCFD1 -0.32 -6.46 -0.33 3.7e-10 Cognitive function; LIHC cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg05564831 chr3:52568323 NT5DC2 0.37 5.83 0.3 1.27e-8 Bipolar disorder; LIHC cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.88 0.39 4.53e-14 Prudent dietary pattern; LIHC trans rs11098499 0.580 rs12509234 chr4:120319434 T/C cg25214090 chr10:38739885 LOC399744 0.6 9.75 0.47 5.57e-20 Corneal astigmatism; LIHC cis rs6598955 0.724 rs12068388 chr1:26621596 G/A cg00852783 chr1:26633632 UBXN11 0.5 8.27 0.41 3.03e-15 Obesity-related traits; LIHC cis rs9534463 0.667 rs7999058 chr13:47216812 C/G cg04092803 chr13:47240378 LRCH1 -0.27 -5.98 -0.31 5.56e-9 Platelet distribution width; LIHC cis rs7666738 0.830 rs6825211 chr4:98807698 A/T cg05340658 chr4:99064831 C4orf37 0.63 11.49 0.53 4.5e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg22907277 chr7:1156413 C7orf50 0.45 6.43 0.33 4.42e-10 Longevity;Endometriosis; LIHC cis rs4631830 0.720 rs2611471 chr10:51503559 G/C cg16070123 chr10:51489643 NA -0.38 -5.97 -0.31 6.05e-9 Prostate-specific antigen levels; LIHC cis rs1055129 0.537 rs10852766 chr17:73951864 T/C cg10935138 chr17:73851978 WBP2 -0.48 -6.97 -0.35 1.65e-11 White matter hyperintensity burden; LIHC cis rs858239 0.539 rs6949363 chr7:23192394 A/G cg23682824 chr7:23144976 KLHL7 0.42 6.25 0.32 1.25e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs4908768 0.871 rs4908775 chr1:8794410 G/A cg20416874 chr1:8611966 RERE 0.49 7.0 0.35 1.35e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs782590 0.683 rs782633 chr2:55898203 A/G cg03859395 chr2:55845619 SMEK2 0.78 13.22 0.58 1.57e-32 Metabolic syndrome; LIHC cis rs2279817 1.000 rs4920620 chr1:18023154 A/G cg21791023 chr1:18019539 ARHGEF10L 0.62 8.73 0.43 1.15e-16 Neuroticism; LIHC cis rs6088590 1.000 rs6120750 chr20:33465289 A/C cg24642439 chr20:33292090 TP53INP2 0.76 10.22 0.48 1.4e-21 Coronary artery disease; LIHC cis rs317689 0.608 rs650198 chr12:69674595 C/T cg20891283 chr12:69753455 YEATS4 0.53 7.67 0.38 1.76e-13 Response to diuretic therapy; LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg21782813 chr7:2030301 MAD1L1 0.42 7.06 0.36 9.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs2795502 0.873 rs2795527 chr10:43270240 T/C cg20628663 chr10:43360327 NA -0.47 -7.21 -0.36 3.65e-12 Blood protein levels; LIHC cis rs16854884 0.657 rs920159 chr3:143753194 A/T cg06585982 chr3:143692056 C3orf58 0.55 7.21 0.36 3.58e-12 Economic and political preferences (feminism/equality); LIHC cis rs6988636 1.000 rs28542077 chr8:124190896 T/C cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs700651 0.754 rs1518367 chr2:198807015 T/A cg03934865 chr2:198174659 NA 0.47 6.9 0.35 2.47e-11 Intracranial aneurysm; LIHC cis rs2404602 0.692 rs8024476 chr15:76983954 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.96 0.31 6.36e-9 Blood metabolite levels; LIHC cis rs2404602 0.622 rs11632365 chr15:77139080 G/A cg23625390 chr15:77176239 SCAPER -0.47 -7.33 -0.37 1.63e-12 Blood metabolite levels; LIHC trans rs4906332 0.966 rs2065016 chr14:103879656 T/A cg17675199 chr6:35436792 RPL10A 0.31 6.1 0.31 2.85e-9 Coronary artery disease; LIHC cis rs10426930 0.844 rs58250802 chr19:5034575 C/T cg18473234 chr19:5097819 KDM4B 0.54 6.61 0.34 1.5e-10 Monocyte percentage of white cells; LIHC trans rs4332037 0.950 rs11767515 chr7:1941051 C/T cg11693508 chr17:37793320 STARD3 0.73 7.55 0.38 4.04e-13 Bipolar disorder; LIHC cis rs1873147 0.569 rs11636033 chr15:63311091 G/T cg21584241 chr15:63341463 TPM1 -0.42 -6.31 -0.32 8.84e-10 Orofacial clefts; LIHC cis rs2075371 0.829 rs11770521 chr7:133936251 A/C cg11752832 chr7:134001865 SLC35B4 0.45 5.8 0.3 1.5e-8 Mean platelet volume; LIHC cis rs1003719 0.591 rs2040125 chr21:38549236 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.55 6.97 0.35 1.69e-11 Eye color traits; LIHC cis rs17152411 0.843 rs7904691 chr10:126582927 G/T cg07906193 chr10:126599966 NA 0.43 6.84 0.35 3.73e-11 Height; LIHC cis rs66569888 0.789 rs17213078 chr2:106734065 G/A cg00318621 chr2:106887213 NA -0.58 -5.96 -0.31 6.17e-9 Facial morphology (factor 23); LIHC cis rs1475911 1.000 rs12482477 chr21:43517233 T/A cg19766460 chr21:43528205 UMODL1;C21orf128 0.83 12.3 0.55 5.05e-29 IgG glycosylation; LIHC cis rs1003719 1.000 rs1003719 chr21:38491095 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.75 11.4 0.52 9.85e-26 Eye color traits; LIHC cis rs372883 0.648 rs1003772 chr21:30736145 A/T cg24692254 chr21:30365293 RNF160 0.52 6.55 0.33 2.09e-10 Pancreatic cancer; LIHC cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.46 -0.33 3.53e-10 Gut microbiome composition (summer); LIHC cis rs7208859 0.573 rs73267872 chr17:29067207 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 1.000 rs2036264 chr7:65799904 G/A cg18876405 chr7:65276391 NA -0.36 -6.58 -0.34 1.74e-10 Aortic root size; LIHC trans rs6598955 0.671 rs11247904 chr1:26621804 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.73 -7.75 -0.39 1.03e-13 Obesity-related traits; LIHC trans rs783540 0.967 rs783527 chr15:83285847 C/T cg18393722 chr15:85113863 UBE2QP1 -0.38 -6.7 -0.34 8.41e-11 Schizophrenia; LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg05484376 chr2:27715224 FNDC4 0.37 6.41 0.33 4.8e-10 Total body bone mineral density; LIHC cis rs916888 0.779 rs430685 chr17:44859148 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg06238570 chr21:40685208 BRWD1 0.48 7.73 0.39 1.22e-13 Cognitive function; LIHC cis rs1018836 0.786 rs10086401 chr8:91572818 C/T cg16814680 chr8:91681699 NA -0.54 -8.46 -0.42 7.9e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs765787 0.530 rs4238376 chr15:45541887 T/C cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg07172676 chr8:144997714 PLEC1 0.44 6.46 0.33 3.57e-10 Alopecia areata; LIHC cis rs3806843 0.771 rs2563334 chr5:140107065 C/G cg19875535 chr5:140030758 IK -0.41 -6.7 -0.34 8.83e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg16822855 chr3:40428330 ENTPD3 0.32 5.76 0.3 1.85e-8 Renal cell carcinoma; LIHC cis rs11888559 0.655 rs10932007 chr2:204005409 T/A cg24605529 chr2:203879461 NBEAL1 0.77 5.85 0.3 1.16e-8 Height; LIHC cis rs7903847 0.642 rs61863819 chr10:99142400 T/C cg08345082 chr10:99160200 RRP12 -0.37 -6.26 -0.32 1.13e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg19635926 chr16:89946313 TCF25 0.57 7.54 0.38 4.19e-13 Skin colour saturation; LIHC cis rs12579753 0.869 rs17692407 chr12:82171369 G/C cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC trans rs875971 0.660 rs10215132 chr7:66054406 C/A cg26939375 chr7:64535504 NA -0.43 -7.01 -0.35 1.28e-11 Aortic root size; LIHC cis rs9649465 1.000 rs3779260 chr7:123348315 A/G cg03229431 chr7:123269106 ASB15 0.37 8.01 0.4 1.88e-14 Migraine; LIHC cis rs1419980 0.730 rs11054877 chr12:7771545 A/G cg10578777 chr12:7781093 NA -0.39 -5.84 -0.3 1.23e-8 HDL cholesterol levels; LIHC cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg20295408 chr7:1910781 MAD1L1 -0.48 -7.01 -0.35 1.29e-11 Bipolar disorder and schizophrenia; LIHC cis rs858239 0.699 rs1881200 chr7:23201637 T/C cg18081818 chr7:23246105 NA 0.46 6.93 0.35 2.16e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs116095464 0.510 rs60844864 chr5:267000 A/G cg00938859 chr5:1591904 SDHAP3 0.56 6.77 0.34 5.68e-11 Breast cancer; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs910316 0.712 rs175074 chr14:75504454 G/A cg08847533 chr14:75593920 NEK9 -0.88 -18.19 -0.7 3.42e-52 Height; LIHC cis rs28735056 1.000 rs3826576 chr18:77633976 G/A cg20368463 chr18:77673604 PQLC1 -0.36 -6.2 -0.32 1.67e-9 Schizophrenia; LIHC cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg13409248 chr3:40428643 ENTPD3 0.41 6.77 0.34 5.65e-11 Renal cell carcinoma; LIHC cis rs12980942 0.630 rs7257825 chr19:41788344 T/C cg25627403 chr19:41769009 HNRNPUL1 0.5 6.29 0.32 9.54e-10 Coronary artery disease; LIHC cis rs7020830 0.898 rs308492 chr9:37298020 C/T cg14294708 chr9:37120828 ZCCHC7 1.04 21.5 0.76 1.83e-65 Schizophrenia; LIHC cis rs11105298 0.891 rs4842653 chr12:89834113 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.37 -0.37 1.25e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs694739 0.628 rs508168 chr11:64135435 G/A cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.02e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs7131987 0.868 rs10771508 chr12:29414211 G/A cg00204748 chr12:29376779 FAR2 0.44 8.32 0.41 2.08e-15 QT interval; LIHC cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg18230493 chr5:56204884 C5orf35 -0.5 -6.7 -0.34 8.68e-11 Initial pursuit acceleration; LIHC cis rs1823913 0.927 rs35530564 chr2:192112050 T/G cg12404831 chr2:192114017 MYO1B 0.32 6.45 0.33 3.82e-10 Obesity-related traits; LIHC trans rs11098499 0.866 rs7665125 chr4:120402079 G/T cg25214090 chr10:38739885 LOC399744 0.49 8.13 0.4 8.18e-15 Corneal astigmatism; LIHC cis rs7617480 0.648 rs4974088 chr3:48898749 T/C cg07636037 chr3:49044803 WDR6 0.76 9.04 0.44 1.15e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg18357526 chr6:26021779 HIST1H4A 0.41 6.2 0.32 1.62e-9 Height; LIHC cis rs2191566 1.000 rs384544 chr19:44505255 A/T cg20607764 chr19:44506953 ZNF230 0.43 6.79 0.34 4.84e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs62458065 0.640 rs10241303 chr7:32534203 T/G cg06627557 chr7:32535165 LSM5;AVL9 -0.74 -7.13 -0.36 6.12e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs10193935 1.000 rs10210866 chr2:42387879 A/G cg27598129 chr2:42591480 NA -0.74 -11.6 -0.53 1.92e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs600806 0.778 rs10857787 chr1:110010289 C/T cg11161837 chr1:110010384 SYPL2 0.46 6.43 0.33 4.41e-10 Intelligence (multi-trait analysis); LIHC cis rs10193935 0.901 rs13384885 chr2:42536646 G/C cg27598129 chr2:42591480 NA -0.72 -10.75 -0.5 2e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg13047869 chr3:10149882 C3orf24 0.52 6.69 0.34 9.06e-11 Alzheimer's disease; LIHC cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg11062466 chr8:58055876 NA 0.39 5.73 0.3 2.23e-8 Developmental language disorder (linguistic errors); LIHC cis rs4925386 0.681 rs2427294 chr20:60927257 G/A cg24112000 chr20:60950667 NA -0.43 -5.72 -0.3 2.37e-8 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs4474465 1.000 rs11237522 chr11:78209879 A/G cg27205649 chr11:78285834 NARS2 -0.4 -6.31 -0.32 8.54e-10 Alzheimer's disease (survival time); LIHC cis rs7197653 0.748 rs8063446 chr16:68344363 A/C cg05110241 chr16:68378359 PRMT7 -0.9 -8.2 -0.41 4.89e-15 Magnesium levels; LIHC cis rs6754311 0.509 rs10188066 chr2:136539513 G/A cg07305463 chr2:136567211 LCT 0.36 6.53 0.33 2.31e-10 Mosquito bite size; LIHC cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg08499158 chr17:42289980 UBTF -0.5 -8.13 -0.4 7.94e-15 Total body bone mineral density; LIHC trans rs1493916 0.777 rs1941685 chr18:31304318 G/T cg27147174 chr7:100797783 AP1S1 -0.46 -6.56 -0.33 1.97e-10 Life satisfaction; LIHC cis rs3768617 0.510 rs4652776 chr1:183091920 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC trans rs875971 0.545 rs3936065 chr7:65790564 C/T cg26939375 chr7:64535504 NA 0.4 6.34 0.32 7.06e-10 Aortic root size; LIHC cis rs16828019 0.852 rs12022978 chr1:41554088 A/G cg03962019 chr1:41807865 NA 0.51 7.43 0.37 8.87e-13 Intelligence (multi-trait analysis); LIHC cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg13393036 chr8:95962371 TP53INP1 -0.4 -8.93 -0.44 2.57e-17 Type 2 diabetes; LIHC cis rs35110281 0.837 rs2838342 chr21:45077865 G/A cg21573476 chr21:45109991 RRP1B -0.5 -9.42 -0.45 7.14e-19 Mean corpuscular volume; LIHC cis rs1789 0.786 rs6449161 chr4:15692954 A/G cg21329975 chr4:15471214 CC2D2A -0.41 -5.97 -0.31 5.94e-9 Blood protein levels; LIHC cis rs611744 0.967 rs628340 chr8:109189425 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs9914544 0.583 rs11078422 chr17:18804413 C/T cg21372672 chr17:16614065 CCDC144A -0.25 -6.2 -0.32 1.62e-9 Educational attainment (years of education); LIHC cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.26 -0.55 6.75e-29 Alzheimer's disease; LIHC cis rs12142240 0.698 rs6684274 chr1:46810842 A/G cg00530320 chr1:46809349 NSUN4 -0.56 -6.27 -0.32 1.11e-9 Menopause (age at onset); LIHC trans rs2073499 1.000 rs79499880 chr3:50259551 A/G cg21659725 chr3:3221576 CRBN 0.66 6.47 0.33 3.34e-10 Schizophrenia; LIHC cis rs2404602 1.000 rs12441433 chr15:76816015 G/A cg23625390 chr15:77176239 SCAPER 0.39 6.63 0.34 1.3e-10 Blood metabolite levels; LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg02782426 chr3:40428986 ENTPD3 0.34 6.18 0.32 1.77e-9 Renal cell carcinoma; LIHC trans rs66887589 0.807 rs9799664 chr4:120326678 C/T cg25214090 chr10:38739885 LOC399744 0.42 6.93 0.35 2.15e-11 Diastolic blood pressure; LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.85e-9 Total body bone mineral density; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg24209194 chr3:40518798 ZNF619 -0.63 -9.6 -0.46 1.82e-19 Renal cell carcinoma; LIHC trans rs4843747 0.671 rs74729706 chr16:88104159 C/T cg26811252 chr16:29126840 RRN3P2 0.42 6.91 0.35 2.42e-11 Menopause (age at onset); LIHC cis rs5753618 0.509 rs4820951 chr22:31586248 G/A cg07713946 chr22:31675144 LIMK2 -0.42 -7.41 -0.37 9.8e-13 Colorectal cancer; LIHC cis rs1008375 0.931 rs3796814 chr4:17602033 G/C cg16339924 chr4:17578868 LAP3 0.41 5.73 0.3 2.25e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg13409248 chr3:40428643 ENTPD3 0.5 8.38 0.41 1.36e-15 Renal cell carcinoma; LIHC cis rs6516091 0.706 rs62199230 chr20:6050124 G/C cg25325723 chr20:6104886 FERMT1 -0.71 -5.88 -0.3 9.8e-9 Abdominal aortic aneurysm; LIHC cis rs17818399 0.620 rs1080871 chr2:46854708 A/G cg02822958 chr2:46747628 ATP6V1E2 0.37 5.87 0.3 1.01e-8 Height; LIHC cis rs3748682 0.861 rs72661832 chr1:38260733 C/T cg12658694 chr1:38397304 INPP5B 0.43 5.9 0.3 8.66e-9 Hypothyroidism; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg07332563 chr6:291687 DUSP22 -0.51 -7.27 -0.37 2.51e-12 Menopause (age at onset); LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg11070056 chr1:107600091 PRMT6 -0.72 -12.36 -0.56 3e-29 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs611744 0.967 rs2597654 chr8:109221090 A/G cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.32e-16 Dupuytren's disease; LIHC cis rs10792665 0.649 rs11233432 chr11:82739753 C/T cg24227371 chr11:82718527 RAB30 -0.38 -9.11 -0.44 6.96e-18 Obesity-related traits; LIHC cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9399135 0.967 rs9389254 chr6:135330709 C/T cg22676075 chr6:135203613 NA 0.39 6.33 0.32 7.87e-10 Red blood cell count; LIHC cis rs116248771 0.690 rs73156490 chr3:158416484 G/A cg16708174 chr3:158430962 RARRES1 0.48 6.34 0.32 7.39e-10 diarrhoeal disease at age 2; LIHC cis rs4808199 1.000 rs60003758 chr19:19557353 A/G cg03709012 chr19:19516395 GATAD2A 1.08 19.4 0.72 4.5e-57 Nonalcoholic fatty liver disease; LIHC cis rs9309473 0.607 rs1851546 chr2:73591127 C/A cg20560298 chr2:73613845 ALMS1 -0.44 -6.89 -0.35 2.71e-11 Metabolite levels; LIHC cis rs9911578 0.805 rs12601867 chr17:56455260 C/G cg12560992 chr17:57184187 TRIM37 -0.84 -13.67 -0.59 3.01e-34 Intelligence (multi-trait analysis); LIHC cis rs240764 0.531 rs1070990 chr6:101264412 T/A cg09795085 chr6:101329169 ASCC3 0.56 7.76 0.39 9.78e-14 Neuroticism; LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs3741404 0.665 rs594461 chr11:63872543 A/G cg18225595 chr11:63971243 STIP1 0.46 7.34 0.37 1.57e-12 Platelet count; LIHC cis rs8044868 0.530 rs2550868 chr16:72066072 G/A cg01557791 chr16:72042693 DHODH -0.39 -6.48 -0.33 3.26e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs699 0.556 rs2478517 chr1:230867887 A/G cg07502417 chr1:230849801 AGT 0.29 6.29 0.32 9.62e-10 Coronary artery disease; LIHC cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg08888203 chr3:10149979 C3orf24 0.56 6.39 0.33 5.49e-10 Alzheimer's disease; LIHC cis rs6754311 0.517 rs60453613 chr2:136527120 G/C cg07169764 chr2:136633963 MCM6 1.04 14.34 0.61 7.85e-37 Mosquito bite size; LIHC cis rs9303401 0.538 rs3785493 chr17:56472119 G/T cg25039879 chr17:56429692 SUPT4H1 -0.86 -9.72 -0.47 7.3e-20 Cognitive test performance; LIHC cis rs2976388 0.587 rs2717606 chr8:143799496 G/A cg06565975 chr8:143823917 SLURP1 0.34 6.66 0.34 1.1e-10 Urinary tract infection frequency; LIHC trans rs8002861 0.967 rs9533690 chr13:44480598 T/C cg17145862 chr1:211918768 LPGAT1 0.67 13.33 0.58 6.19e-33 Leprosy; LIHC cis rs10174077 0.874 rs6750342 chr2:152485754 A/G cg19508488 chr2:152266495 RIF1 0.49 6.88 0.35 2.79e-11 Squamous cell lung carcinoma; LIHC cis rs1997103 0.863 rs2140916 chr7:55403154 A/C cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg27211696 chr2:191398769 TMEM194B 0.66 10.88 0.51 6.96e-24 Pulse pressure; LIHC cis rs12477438 0.666 rs10179910 chr2:99658503 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.47 -7.64 -0.38 2.24e-13 Chronic sinus infection; LIHC cis rs9549367 0.773 rs9549717 chr13:113908826 A/G cg00898013 chr13:113819073 PROZ -0.34 -6.12 -0.31 2.52e-9 Platelet distribution width; LIHC cis rs950776 0.518 rs12916483 chr15:78832397 G/A cg06917634 chr15:78832804 PSMA4 0.95 14.5 0.62 1.75e-37 Sudden cardiac arrest; LIHC cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.64e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs35883536 0.967 rs2050471 chr1:101175651 C/T cg14515779 chr1:101123966 NA -0.65 -12.38 -0.56 2.44e-29 Monocyte count; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13268919 chr11:842945 TSPAN4;POLR2L 0.6 8.81 0.43 6.29e-17 Hepatitis; LIHC cis rs6912958 0.512 rs910563 chr6:88058885 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.59 11.11 0.52 1.06e-24 Monocyte percentage of white cells; LIHC cis rs8083850 0.635 rs12966663 chr18:50849951 G/A cg24270629 chr18:50823537 DCC 0.53 7.97 0.4 2.39e-14 Intelligence (multi-trait analysis); LIHC cis rs35306767 0.669 rs2101051 chr10:1158791 G/T cg26597838 chr10:835615 NA 0.62 5.97 0.31 5.82e-9 Eosinophil percentage of granulocytes; LIHC cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg06453172 chr10:134556979 INPP5A -0.63 -7.97 -0.4 2.43e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs600806 0.745 rs4970763 chr1:110006349 G/A cg16275483 chr1:110013120 SYPL2 -0.51 -6.33 -0.32 7.5e-10 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg05564831 chr3:52568323 NT5DC2 0.35 5.87 0.3 1e-8 Bipolar disorder; LIHC cis rs2760061 0.626 rs594916 chr1:228133544 C/A cg02753203 chr1:228287806 NA -0.46 -7.34 -0.37 1.52e-12 Diastolic blood pressure; LIHC cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg16606324 chr3:10149918 C3orf24 0.54 5.81 0.3 1.4e-8 Alzheimer's disease; LIHC cis rs600806 0.888 rs3853501 chr1:109864374 G/A cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.92 -0.3 7.78e-9 Intelligence (multi-trait analysis); LIHC cis rs1046896 0.553 rs3744160 chr17:80828303 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.33 0.32 7.74e-10 Glycated hemoglobin levels; LIHC trans rs61931739 0.534 rs11053073 chr12:34202412 C/T cg26384229 chr12:38710491 ALG10B 0.55 7.06 0.36 9.12e-12 Morning vs. evening chronotype; LIHC cis rs2637030 0.586 rs1465445 chr5:52848382 A/T cg06476337 chr5:52856530 NDUFS4 0.38 6.3 0.32 9.23e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC trans rs634534 0.561 rs613924 chr11:65769295 C/T cg17712092 chr4:129076599 LARP1B 0.74 13.06 0.58 6.66e-32 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs1577917 0.958 rs12213343 chr6:86443019 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.21 -0.32 1.52e-9 Response to antipsychotic treatment; LIHC cis rs2153535 0.563 rs1737585 chr6:8536594 A/G cg07606381 chr6:8435919 SLC35B3 -0.77 -11.11 -0.51 1.1e-24 Motion sickness; LIHC cis rs921968 0.678 rs689116 chr2:219433888 C/A cg17980119 chr2:219472607 PLCD4 0.34 5.74 0.3 2.08e-8 Mean corpuscular hemoglobin concentration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11739225 chr14:35591523 PPP2R3C;KIAA0391 -0.51 -6.13 -0.31 2.41e-9 Systolic blood pressure; LIHC cis rs311392 0.902 rs1511147 chr8:55091227 C/T cg20636351 chr8:55087400 NA -0.36 -7.58 -0.38 3.31e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs9911578 0.967 rs7503190 chr17:57184162 A/C cg05425664 chr17:57184151 TRIM37 -0.6 -9.0 -0.44 1.61e-17 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.569 rs283793 chr15:76774752 G/A cg03037974 chr15:76606532 NA 0.62 10.58 0.5 7.89e-23 Blood metabolite levels; LIHC cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg17554472 chr22:41940697 POLR3H 0.53 5.75 0.3 1.93e-8 Vitiligo; LIHC trans rs11098499 0.562 rs58583086 chr4:120556362 A/G cg25214090 chr10:38739885 LOC399744 -0.43 -6.99 -0.35 1.44e-11 Corneal astigmatism; LIHC cis rs6840360 1.000 rs6833368 chr4:152603177 C/T cg22705602 chr4:152727874 NA 0.3 6.4 0.33 5.1e-10 Intelligence (multi-trait analysis); LIHC trans rs2235573 0.527 rs139884 chr22:38369976 A/G cg19894588 chr14:64061835 NA 0.46 6.08 0.31 3.24e-9 Glioblastoma;Glioma; LIHC cis rs1538970 0.962 rs7544178 chr1:45819069 C/T cg24296786 chr1:45957014 TESK2 -0.49 -7.17 -0.36 4.64e-12 Platelet count; LIHC cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.26e-51 Menopause (age at onset); LIHC cis rs907683 0.546 rs1058261 chr2:220285309 C/T cg15015639 chr2:220282977 DES -0.37 -9.03 -0.44 1.29e-17 Resting heart rate; LIHC cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg19318889 chr4:1322082 MAEA 0.46 6.48 0.33 3.24e-10 Obesity-related traits; LIHC cis rs7309 0.935 rs6432674 chr2:162025322 G/T cg22496339 chr2:162101262 NA 0.8 13.55 0.59 8.5e-34 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs4319547 1.000 rs4319547 chr12:123079035 A/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.95 -0.39 2.77e-14 Body mass index; LIHC cis rs4631830 0.600 rs11004324 chr10:51496623 G/T cg16070123 chr10:51489643 NA -0.42 -6.13 -0.31 2.43e-9 Prostate-specific antigen levels; LIHC cis rs899997 1.000 rs11634628 chr15:79005579 G/A cg04896959 chr15:78267971 NA 0.4 7.82 0.39 6.8e-14 Coronary artery disease or large artery stroke; LIHC trans rs911555 0.755 rs10144051 chr14:103885931 A/C cg17675199 chr6:35436792 RPL10A 0.38 7.83 0.39 6.17e-14 Intelligence (multi-trait analysis); LIHC cis rs2455799 0.552 rs1472697 chr3:15750268 G/A cg12698662 chr3:15914712 MIR563 -0.41 -7.48 -0.37 6.35e-13 Mean platelet volume; LIHC cis rs6754311 0.593 rs10195620 chr2:136495619 A/T cg25344623 chr2:136566232 LCT 0.44 8.89 0.43 3.53e-17 Mosquito bite size; LIHC cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.91 8.23 0.41 3.98e-15 Platelet count; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26155673 chr8:12052102 FAM86B1 0.47 6.4 0.33 5.11e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg00091569 chr3:40428383 ENTPD3 0.4 6.64 0.34 1.22e-10 Renal cell carcinoma; LIHC cis rs4819052 0.851 rs10470246 chr21:46659017 C/G cg11663144 chr21:46675770 NA -0.33 -6.16 -0.32 2.03e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs55665837 0.519 rs1451677 chr11:14746012 A/C cg16394018 chr11:14927549 NA 0.41 5.85 0.3 1.12e-8 Vitamin D levels; LIHC cis rs875971 0.522 rs709604 chr7:65497434 A/G cg14393609 chr7:65229607 NA -0.44 -6.49 -0.33 3.04e-10 Aortic root size; LIHC cis rs2422052 0.639 rs2113589 chr2:118647316 A/G cg22545206 chr2:118617499 NA 0.36 6.08 0.31 3.25e-9 Mosquito bite size; LIHC cis rs7909074 0.899 rs2026428 chr10:45389452 T/C cg05187965 chr10:45406764 TMEM72 -0.28 -7.2 -0.36 3.87e-12 Mean corpuscular volume; LIHC cis rs10791097 0.506 rs10750446 chr11:130706918 T/C cg12179176 chr11:130786555 SNX19 -0.61 -9.06 -0.44 1.03e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6430585 0.527 rs59413285 chr2:136444185 G/T cg07169764 chr2:136633963 MCM6 0.68 8.6 0.42 2.89e-16 Corneal structure; LIHC cis rs16912285 0.591 rs12796137 chr11:24364459 T/G ch.11.24196551F chr11:24239977 NA 0.68 8.24 0.41 3.83e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs6570726 0.791 rs448939 chr6:145808320 T/C cg23711669 chr6:146136114 FBXO30 0.56 10.18 0.48 2.03e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs2243480 1.000 rs410128 chr7:65603173 C/T cg10756647 chr7:56101905 PSPH 1.09 12.43 0.56 1.64e-29 Diabetic kidney disease; LIHC cis rs12200782 0.530 rs9379892 chr6:26582414 G/A cg09904177 chr6:26538194 HMGN4 0.45 6.5 0.33 2.93e-10 Small cell lung carcinoma; LIHC cis rs3736485 0.966 rs7176044 chr15:51895343 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.29 -0.32 9.52e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2153535 0.580 rs9505448 chr6:8459804 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs55665837 1.000 rs12283797 chr11:14442262 C/G cg19336497 chr11:14380999 RRAS2 -0.46 -8.45 -0.42 8.57e-16 Vitamin D levels; LIHC cis rs597539 0.689 rs596874 chr11:68630874 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.77 -11.79 -0.54 3.65e-27 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs8081395 0.707 rs1024637 chr17:58038893 C/T cg13753209 chr17:57696993 CLTC -0.38 -5.75 -0.3 2e-8 White blood cell count; LIHC cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg11644478 chr21:40555479 PSMG1 0.82 10.38 0.49 3.99e-22 Cognitive function; LIHC cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg25072359 chr17:41440525 NA 0.39 6.16 0.32 2.01e-9 Menopause (age at onset); LIHC cis rs10089 0.953 rs758180 chr5:127354423 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.35 0.32 6.91e-10 Ileal carcinoids; LIHC cis rs2029362 0.611 rs10219241 chr11:27737123 G/A cg18117895 chr11:27722066 BDNF 0.4 5.95 0.31 6.62e-9 Total body bone mineral density; LIHC cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs950776 0.518 rs2869544 chr15:78839400 G/A cg22563815 chr15:78856949 CHRNA5 -0.37 -6.78 -0.34 5.25e-11 Sudden cardiac arrest; LIHC cis rs1707322 1.000 rs4660332 chr1:46461418 T/A cg06784218 chr1:46089804 CCDC17 0.39 6.9 0.35 2.58e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10870270 1.000 rs7078692 chr10:133775370 T/A cg08754478 chr10:133766260 PPP2R2D -0.55 -8.1 -0.4 9.8e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs637571 0.512 rs660118 chr11:65735174 G/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.82 0.43 5.98e-17 Eosinophil percentage of white cells; LIHC cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.59 -8.53 -0.42 4.85e-16 Lymphocyte counts; LIHC cis rs713477 0.967 rs61976571 chr14:55908774 T/C cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.32e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs8017423 0.967 rs4904656 chr14:90721442 G/T cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 2.97e-9 Mortality in heart failure; LIHC cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg12311346 chr5:56204834 C5orf35 -0.57 -7.46 -0.37 7.05e-13 Initial pursuit acceleration; LIHC cis rs116095464 0.558 rs61492827 chr5:225774 A/G cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -10.25 -0.48 1.12e-21 Platelet count; LIHC cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg06640241 chr16:89574553 SPG7 0.86 16.28 0.66 1.57e-44 Multiple myeloma (IgH translocation); LIHC trans rs12620999 0.938 rs4575672 chr2:238070572 T/C cg15676719 chr1:167598521 RCSD1 -0.38 -6.79 -0.34 4.83e-11 Systemic lupus erythematosus; LIHC cis rs2302190 0.769 rs7211294 chr17:56462783 G/A cg12560992 chr17:57184187 TRIM37 0.68 8.35 0.41 1.78e-15 Vitamin D levels; LIHC cis rs6973256 0.637 rs12707116 chr7:133424909 C/T cg10665199 chr7:133106180 EXOC4 -0.33 -5.82 -0.3 1.38e-8 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.846 rs13083229 chr3:161008125 G/A cg03342759 chr3:160939853 NMD3 -0.8 -13.17 -0.58 2.51e-32 Morning vs. evening chronotype; LIHC cis rs748404 0.660 rs694725 chr15:43756210 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.3 0.37 1.99e-12 Lung cancer; LIHC cis rs782590 0.902 rs3762513 chr2:55762957 C/T cg03859395 chr2:55845619 SMEK2 0.9 15.34 0.64 9.08e-41 Metabolic syndrome; LIHC cis rs6450176 0.909 rs67199213 chr5:53290648 A/G ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.29 -0.64 1.35e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs3960554 0.660 rs55671363 chr7:75793405 T/C cg04610667 chr7:75704037 NA -0.36 -6.14 -0.31 2.33e-9 Eotaxin levels; LIHC cis rs10256972 0.630 rs10282584 chr7:1081442 C/T cg16145915 chr7:1198662 ZFAND2A -0.31 -7.29 -0.37 2.15e-12 Longevity;Endometriosis; LIHC trans rs10162376 1 rs10162376 chr14:81030493 C/T cg20999565 chr14:68265668 ZFYVE26 0.72 6.47 0.33 3.45e-10 Mild influenza (H1N1) infection; LIHC cis rs72781680 1.000 rs72796328 chr2:24141343 A/G cg08917208 chr2:24149416 ATAD2B 0.93 8.0 0.4 1.96e-14 Lymphocyte counts; LIHC cis rs61990749 0.597 rs7142390 chr14:78232880 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.62 10.15 0.48 2.51e-21 Fibroblast growth factor basic levels; LIHC cis rs2625529 0.526 rs8031386 chr15:72508799 C/A cg16672083 chr15:72433130 SENP8 -0.31 -5.91 -0.3 8.11e-9 Red blood cell count; LIHC cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6942756 0.774 rs66479871 chr7:129009687 T/C cg02491457 chr7:128862824 NA -0.54 -8.21 -0.41 4.52e-15 White matter hyperintensity burden; LIHC cis rs11190604 1.000 rs7073586 chr10:102307671 A/G cg07080220 chr10:102295463 HIF1AN 0.51 7.36 0.37 1.37e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs916888 0.821 rs199506 chr17:44859031 A/G cg13957321 chr17:43675089 NA -0.49 -7.82 -0.39 6.47e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4819052 0.679 rs2236450 chr21:46702553 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 10.25 0.48 1.12e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10489202 0.657 rs201540 chr1:167992883 G/A cg24449463 chr1:168025552 DCAF6 -0.64 -9.74 -0.47 6.18e-20 Schizophrenia; LIHC cis rs477692 0.569 rs1771448 chr10:131296201 A/G cg05714579 chr10:131428358 MGMT -0.43 -6.83 -0.35 3.84e-11 Response to temozolomide; LIHC trans rs877282 0.838 rs11253408 chr10:796374 T/C cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs6424115 0.965 rs2502979 chr1:24149315 C/A cg10978503 chr1:24200527 CNR2 0.38 8.99 0.44 1.77e-17 Immature fraction of reticulocytes; LIHC cis rs2242116 0.796 rs7645278 chr3:46974100 A/C cg16586182 chr3:47516702 SCAP -0.4 -6.83 -0.35 3.81e-11 Birth weight; LIHC cis rs853679 0.517 rs4713143 chr6:28106759 A/C cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs3806843 1.000 rs1548699 chr5:140164918 T/C cg19875535 chr5:140030758 IK 0.36 5.95 0.31 6.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2522056 0.935 rs757104 chr5:131795229 T/C cg24060327 chr5:131705240 SLC22A5 0.52 6.94 0.35 1.95e-11 Lymphocyte counts;Fibrinogen; LIHC cis rs6684514 0.506 rs3762281 chr1:156304782 A/G cg10096929 chr1:156261403 TMEM79 0.36 6.24 0.32 1.32e-9 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs10419226 0.555 rs3829671 chr19:18777667 T/C cg16673477 chr19:18812017 CRTC1 -0.34 -5.73 -0.3 2.17e-8 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7927592 0.871 rs55953412 chr11:68328283 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.23 -0.32 1.33e-9 Total body bone mineral density; LIHC cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg07424592 chr7:64974309 NA 0.82 9.58 0.46 2.09e-19 Diabetic kidney disease; LIHC cis rs9911578 0.839 rs1871751 chr17:57190368 A/G cg12560992 chr17:57184187 TRIM37 0.93 15.91 0.65 4.57e-43 Intelligence (multi-trait analysis); LIHC cis rs7106204 0.514 rs1443044 chr11:24255575 C/G ch.11.24196551F chr11:24239977 NA -0.83 -12.0 -0.54 6.06e-28 Response to Homoharringtonine (cytotoxicity); LIHC cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg13395646 chr4:1353034 KIAA1530 -0.44 -6.44 -0.33 4.05e-10 Longevity; LIHC cis rs8180040 0.620 rs7373821 chr3:47080127 A/C cg27129171 chr3:47204927 SETD2 0.54 9.08 0.44 8.92e-18 Colorectal cancer; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg07332563 chr6:291687 DUSP22 -0.52 -7.55 -0.38 3.89e-13 Menopause (age at onset); LIHC cis rs950169 0.545 rs4842841 chr15:84641125 G/A cg17507749 chr15:85114479 UBE2QP1 0.64 5.81 0.3 1.43e-8 Schizophrenia; LIHC cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.18e-17 Bipolar disorder; LIHC cis rs722599 0.748 rs59112602 chr14:75358817 C/G cg08847533 chr14:75593920 NEK9 -0.56 -9.0 -0.44 1.56e-17 IgG glycosylation; LIHC cis rs4727027 0.933 rs6955564 chr7:148866173 A/G cg23583168 chr7:148888333 NA -0.59 -8.61 -0.42 2.77e-16 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs782590 0.935 rs2627779 chr2:55892356 A/G cg18811423 chr2:55921094 PNPT1 0.9 14.1 0.61 6.38e-36 Metabolic syndrome; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg10815395 chr12:49237807 DDX23 0.61 6.49 0.33 2.93e-10 Mean platelet volume; LIHC cis rs7635838 0.684 rs2594968 chr3:11352442 T/C cg00170343 chr3:11313890 ATG7 0.6 10.28 0.49 8.76e-22 HDL cholesterol; LIHC cis rs1799949 1.000 rs35070007 chr17:41316747 C/G cg23758822 chr17:41437982 NA -0.92 -17.21 -0.68 3e-48 Menopause (age at onset); LIHC cis rs2304069 0.565 rs13183261 chr5:149421847 T/G cg12661370 chr5:149340060 SLC26A2 0.52 7.64 0.38 2.17e-13 HIV-1 control; LIHC cis rs1395 0.710 rs11682913 chr2:27473649 G/A cg23587288 chr2:27483067 SLC30A3 -0.34 -6.28 -0.32 1.04e-9 Blood metabolite levels; LIHC cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg07424592 chr7:64974309 NA 0.8 9.16 0.44 4.94e-18 Diabetic kidney disease; LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg26338869 chr17:61819248 STRADA -0.46 -6.14 -0.32 2.3e-9 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21139845 chr12:7053993 C12orf57 0.48 7.07 0.36 8.75e-12 Cognitive function; LIHC cis rs9399135 0.967 rs9376085 chr6:135371224 T/C cg24558204 chr6:135376177 HBS1L 0.42 6.81 0.35 4.49e-11 Red blood cell count; LIHC cis rs8017423 0.967 rs4904662 chr14:90729427 G/A cg14092571 chr14:90743983 NA -0.42 -6.57 -0.33 1.87e-10 Mortality in heart failure; LIHC cis rs13064411 0.696 rs1386336 chr3:113144153 C/T cg18753928 chr3:113234510 CCDC52 -0.43 -5.9 -0.3 8.89e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs8180040 0.966 rs1872164 chr3:47415100 G/A cg16586182 chr3:47516702 SCAP 0.61 11.87 0.54 1.84e-27 Colorectal cancer; LIHC cis rs4700695 0.719 rs36922 chr5:65464856 C/T cg21114390 chr5:65439923 SFRS12 -0.59 -8.31 -0.41 2.27e-15 Facial morphology (factor 19); LIHC cis rs2576037 0.566 rs2437854 chr18:44557613 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.73 -11.25 -0.52 3.43e-25 Personality dimensions; LIHC cis rs2576037 0.507 rs2571019 chr18:44585287 A/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.41 5.83 0.3 1.26e-8 Personality dimensions; LIHC cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg12463550 chr7:65579703 CRCP 0.69 7.15 0.36 5.29e-12 Diabetic kidney disease; LIHC cis rs12586317 0.620 rs17091786 chr14:35565856 A/T cg16230307 chr14:35515116 FAM177A1 0.8 13.39 0.59 3.54e-33 Psoriasis; LIHC cis rs11229555 0.645 rs36002376 chr11:58204809 C/G cg15696309 chr11:58395628 NA -0.65 -7.67 -0.38 1.76e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1816752 0.935 rs4770676 chr13:25003883 A/G cg02811702 chr13:24901961 NA 0.25 6.06 0.31 3.59e-9 Obesity-related traits; LIHC cis rs2455601 0.786 rs56680262 chr11:8971555 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -6.01 -0.31 4.84e-9 Schizophrenia; LIHC cis rs1707322 0.716 rs6694889 chr1:46101806 A/C cg06784218 chr1:46089804 CCDC17 0.42 7.69 0.38 1.59e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs35160687 0.644 rs4832272 chr2:86516211 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 0.38 6.02 0.31 4.58e-9 Night sleep phenotypes; LIHC cis rs9911578 1.000 rs9902994 chr17:56948722 T/A cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs10791097 0.694 rs1054869 chr11:130742630 G/A cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs67478160 0.654 rs11628240 chr14:104218135 A/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.68 0.57 1.8e-30 Schizophrenia; LIHC cis rs7107174 1.000 rs7107174 chr11:77997936 C/T cg02023728 chr11:77925099 USP35 0.51 9.63 0.46 1.45e-19 Testicular germ cell tumor; LIHC cis rs2235642 0.750 rs2755185 chr16:1645827 A/G cg03034668 chr16:1723424 CRAMP1L -0.38 -6.75 -0.34 6.37e-11 Coronary artery disease; LIHC cis rs2380220 0.606 rs9488080 chr6:96006973 A/G cg04719120 chr6:96025338 MANEA 0.52 6.58 0.34 1.78e-10 Behavioural disinhibition (generation interaction); LIHC cis rs4803468 0.967 rs7259900 chr19:41889429 A/T cg14132834 chr19:41945861 ATP5SL -0.4 -5.91 -0.3 8.35e-9 Height; LIHC cis rs2304069 0.954 rs1962603 chr5:149393006 G/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.97 12.64 0.56 2.66e-30 HIV-1 control; LIHC cis rs9733 0.650 rs11204684 chr1:150608894 A/G cg13175981 chr1:150552382 MCL1 0.65 10.21 0.48 1.52e-21 Tonsillectomy; LIHC trans rs561341 1.000 rs546519 chr17:30297682 T/G cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 8.04e-24 Hip circumference adjusted for BMI; LIHC cis rs600806 0.778 rs10857787 chr1:110010289 C/T cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.94 -0.39 2.98e-14 Intelligence (multi-trait analysis); LIHC cis rs4665809 1.000 rs750450 chr2:26324631 A/G cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.05e-15 Gut microbiome composition (summer); LIHC cis rs523522 0.962 rs4767903 chr12:120930046 G/A cg12219531 chr12:120966889 COQ5 0.66 13.13 0.58 3.66e-32 High light scatter reticulocyte count; LIHC cis rs4478037 0.749 rs9311003 chr3:33131070 A/G cg16652328 chr3:33138982 GLB1;TMPPE 0.59 8.13 0.4 7.79e-15 Major depressive disorder; LIHC cis rs9318086 0.578 rs2077709 chr13:24476073 A/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.52 -10.29 -0.49 8.23e-22 Myopia (pathological); LIHC cis rs208520 0.874 rs208473 chr6:66917265 G/C cg07460842 chr6:66804631 NA -0.7 -7.81 -0.39 7.21e-14 Exhaled nitric oxide output; LIHC cis rs2760061 0.717 rs708117 chr1:228199902 G/A cg02753203 chr1:228287806 NA 0.49 8.08 0.4 1.1e-14 Diastolic blood pressure; LIHC cis rs8180040 0.603 rs9854790 chr3:47101306 T/G cg27129171 chr3:47204927 SETD2 0.57 9.39 0.45 8.92e-19 Colorectal cancer; LIHC cis rs7618501 1.000 rs11130221 chr3:49819102 C/G cg24110177 chr3:50126178 RBM5 -0.44 -6.75 -0.34 6.3e-11 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.520 rs2171359 chr2:99795360 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.16 0.77 4.33e-68 Chronic sinus infection; LIHC cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg13866156 chr1:1669148 SLC35E2 -0.68 -12.95 -0.57 1.76e-31 Body mass index; LIHC cis rs769267 0.965 rs1010207 chr19:19416045 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.61 9.57 0.46 2.16e-19 Tonsillectomy; LIHC cis rs10896135 0.526 rs12795774 chr11:66381517 T/C cg24851651 chr11:66362959 CCS -0.37 -6.05 -0.31 3.83e-9 Bipolar disorder; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg00280220 chr17:61926910 NA 0.44 7.16 0.36 5.04e-12 Prudent dietary pattern; LIHC cis rs17826219 0.706 rs8075107 chr17:29106649 C/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Body mass index; LIHC cis rs739401 0.619 rs10766482 chr11:2961600 C/T cg25174290 chr11:3078921 CARS 0.57 8.7 0.43 1.46e-16 Longevity; LIHC cis rs9309711 0.666 rs4321399 chr2:3481659 G/A cg04359351 chr2:3481828 TTC15 0.28 5.95 0.31 6.77e-9 Neurofibrillary tangles; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg03336678 chr3:40547435 ZNF620 0.47 6.28 0.32 1.05e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg04267008 chr7:1944627 MAD1L1 -0.67 -11.2 -0.52 5.05e-25 Bipolar disorder and schizophrenia; LIHC cis rs9790314 0.846 rs4470535 chr3:160974468 G/A cg03342759 chr3:160939853 NMD3 -0.76 -11.16 -0.52 7.29e-25 Morning vs. evening chronotype; LIHC cis rs796364 0.806 rs34582889 chr2:201010527 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.66 -7.66 -0.38 1.96e-13 Schizophrenia; LIHC cis rs1559088 1.000 rs1559088 chr19:33551061 C/T cg27124370 chr19:33622961 WDR88 0.46 7.04 0.36 1.04e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9902453 0.935 rs7220151 chr17:28334710 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs35306767 0.761 rs12770910 chr10:1050318 A/G cg20503657 chr10:835505 NA 0.83 7.99 0.4 2.07e-14 Eosinophil percentage of granulocytes; LIHC cis rs5769765 0.908 rs9627800 chr22:50319351 T/C cg26441486 chr22:50317300 CRELD2 0.39 6.59 0.34 1.65e-10 Schizophrenia; LIHC cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg07424592 chr7:64974309 NA 0.8 9.43 0.45 6.25e-19 Diabetic kidney disease; LIHC cis rs644799 0.932 rs523934 chr11:95641775 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.62 8.49 0.42 6.3e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4819052 0.679 rs2838860 chr21:46684904 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 10.0 0.48 7.89e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs12692119 0.655 rs7420828 chr2:127652836 C/G cg13995918 chr5:1280305 TERT -0.45 -6.31 -0.32 8.83e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs1005277 0.579 rs176886 chr10:38403974 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12744310 0.945 rs1343776 chr1:41757718 G/A cg03962019 chr1:41807865 NA 0.38 6.14 0.32 2.31e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7296418 0.961 rs4148862 chr12:123568619 A/C cg06742321 chr12:123595122 PITPNM2 0.31 5.96 0.31 6.42e-9 Platelet count; LIHC cis rs2777491 0.574 rs316611 chr15:41751678 A/G cg18705301 chr15:41695430 NDUFAF1 1.13 15.69 0.65 3.75e-42 Ulcerative colitis; LIHC cis rs796364 1.000 rs769950 chr2:200730028 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.09 0.44 8.32e-18 Schizophrenia; LIHC cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg21782813 chr7:2030301 MAD1L1 0.37 6.32 0.32 8.28e-10 Bipolar disorder and schizophrenia; LIHC cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg11644478 chr21:40555479 PSMG1 -0.39 -6.12 -0.31 2.55e-9 Menarche (age at onset); LIHC cis rs12086130 0.892 rs10888713 chr1:51463424 A/T cg07174182 chr1:51127561 FAF1 -0.92 -9.89 -0.47 1.9e-20 Hip circumference adjusted for BMI;Hip circumference; LIHC trans rs6058796 1.000 rs57861317 chr20:31260708 C/T cg02600331 chr11:130417168 NA 0.36 7.75 0.39 1.03e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg16405210 chr4:1374714 KIAA1530 -0.45 -6.77 -0.34 5.5e-11 Obesity-related traits; LIHC cis rs10838687 0.736 rs3781620 chr11:47259264 G/C cg25783544 chr11:47291846 MADD 0.46 5.88 0.3 9.79e-9 Proinsulin levels; LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.15e-11 Prudent dietary pattern; LIHC cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg06634786 chr22:41940651 POLR3H -0.67 -7.52 -0.38 4.94e-13 Vitiligo; LIHC cis rs7582180 0.614 rs6737217 chr2:101006267 T/G cg14675211 chr2:100938903 LONRF2 0.54 8.41 0.41 1.09e-15 Intelligence (multi-trait analysis); LIHC cis rs1577917 1.000 rs1577919 chr6:86757296 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.31 -0.37 1.84e-12 Response to antipsychotic treatment; LIHC cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg06212747 chr3:49208901 KLHDC8B 0.63 8.8 0.43 6.79e-17 Menarche (age at onset); LIHC cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg12310025 chr6:25882481 NA 0.53 6.62 0.34 1.4e-10 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs7602534 chr2:27592423 C/T cg05484376 chr2:27715224 FNDC4 0.39 6.53 0.33 2.34e-10 Total body bone mineral density; LIHC cis rs4843747 0.671 rs28679286 chr16:88106307 C/T cg06050784 chr16:88016603 BANP 0.35 6.44 0.33 4.11e-10 Menopause (age at onset); LIHC cis rs4803468 0.967 rs1077856 chr19:41885221 T/C cg14132834 chr19:41945861 ATP5SL -0.39 -5.79 -0.3 1.56e-8 Height; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg21747652 chr5:138238397 CTNNA1 0.37 6.12 0.31 2.53e-9 Myopia (pathological); LIHC trans rs911555 0.755 rs35233301 chr14:103885291 A/G cg17675199 chr6:35436792 RPL10A -0.41 -8.43 -0.41 9.66e-16 Intelligence (multi-trait analysis); LIHC cis rs1865760 1.000 rs2071301 chr6:25914263 G/T cg17691542 chr6:26056736 HIST1H1C 0.39 5.93 0.31 7.51e-9 Height; LIHC trans rs877282 0.898 rs10904546 chr10:757222 A/G cg22713356 chr15:30763199 NA 1.43 12.25 0.55 7.45e-29 Uric acid levels; LIHC cis rs2439831 0.850 rs11856795 chr15:44160582 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.71 9.82 0.47 3.17e-20 Lung cancer in ever smokers; LIHC cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6065325 0.514 rs4810320 chr20:40095031 G/T cg06610464 chr20:40243608 CHD6 0.38 6.16 0.32 2.07e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2576037 0.526 rs4890699 chr18:44541029 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.09 -0.36 7.73e-12 Personality dimensions; LIHC cis rs7264396 0.790 rs2425083 chr20:34300456 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.69 -11.81 -0.54 3.29e-27 Total cholesterol levels; LIHC cis rs920590 0.758 rs7012358 chr8:19662498 C/T cg01411142 chr8:19674711 INTS10 0.51 7.68 0.38 1.74e-13 Acute lymphoblastic leukemia (childhood); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg17440044 chr7:100167198 NA -0.36 -6.07 -0.31 3.49e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs875971 0.522 rs1968127 chr7:66056803 C/T cg18876405 chr7:65276391 NA -0.44 -7.84 -0.39 5.85e-14 Aortic root size; LIHC cis rs7312933 0.670 rs2406568 chr12:42552297 G/C cg17420585 chr12:42539391 GXYLT1 -0.37 -6.0 -0.31 4.93e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1153858 0.945 rs16943246 chr15:45720597 G/A cg26924012 chr15:45694286 SPATA5L1 0.84 15.55 0.64 1.34e-41 Homoarginine levels; LIHC cis rs6691722 0.503 rs3765432 chr1:24706461 A/G cg18323236 chr1:24743029 NIPAL3 0.41 7.47 0.37 6.57e-13 Response to interferon beta in multiple sclerosis; LIHC cis rs9534288 0.762 rs9534285 chr13:46601902 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs10870270 0.957 rs7074604 chr10:133740373 G/C cg08754478 chr10:133766260 PPP2R2D -0.54 -8.03 -0.4 1.54e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs7615952 0.736 rs13063122 chr3:125643860 G/A cg07211511 chr3:129823064 LOC729375 -0.84 -10.47 -0.49 1.93e-22 Blood pressure (smoking interaction); LIHC cis rs12220238 1.000 rs12358614 chr10:75906173 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.71 6.78 0.34 5.19e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7100689 0.646 rs9420370 chr10:82073248 C/T cg00277334 chr10:82204260 NA -0.59 -7.5 -0.38 5.7e-13 Post bronchodilator FEV1; LIHC cis rs240764 0.578 rs6927598 chr6:101232729 T/C cg09795085 chr6:101329169 ASCC3 0.42 5.71 0.3 2.42e-8 Neuroticism; LIHC cis rs10504229 0.954 rs903717 chr8:58167856 A/G cg21724239 chr8:58056113 NA 0.43 6.14 0.32 2.27e-9 Developmental language disorder (linguistic errors); LIHC cis rs3818285 0.610 rs642938 chr10:111633025 A/C cg00817464 chr10:111662876 XPNPEP1 0.67 11.55 0.53 2.69e-26 Superior crus of antihelix expression; LIHC cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg11890956 chr21:40555474 PSMG1 -0.51 -8.52 -0.42 5.04e-16 Menarche (age at onset); LIHC cis rs5769765 0.773 rs9616395 chr22:50317803 A/G cg02269571 chr22:50332266 NA -0.67 -9.08 -0.44 8.72e-18 Schizophrenia; LIHC cis rs7772486 0.624 rs9485018 chr6:146025731 T/C cg23711669 chr6:146136114 FBXO30 -0.63 -11.62 -0.53 1.55e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs72781680 1.000 rs72781632 chr2:24198342 A/C cg08917208 chr2:24149416 ATAD2B 0.95 8.21 0.41 4.55e-15 Lymphocyte counts; LIHC cis rs7208859 0.623 rs9896603 chr17:29078512 C/G cg14067834 chr17:29058358 SUZ12P 0.68 6.69 0.34 9.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg08219700 chr8:58056026 NA 0.5 6.81 0.35 4.4e-11 Developmental language disorder (linguistic errors); LIHC cis rs7520050 0.966 rs6695809 chr1:46285461 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.74 0.3 2.12e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7264396 0.563 rs17093093 chr20:34380925 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.57 -8.03 -0.4 1.63e-14 Total cholesterol levels; LIHC cis rs8180040 0.701 rs11917474 chr3:47010491 G/A cg27129171 chr3:47204927 SETD2 0.62 10.8 0.5 1.4e-23 Colorectal cancer; LIHC cis rs17125944 0.506 rs1998776 chr14:53355590 T/A cg00686598 chr14:53173677 PSMC6 -0.78 -8.8 -0.43 6.93e-17 Alzheimer's disease (late onset); LIHC cis rs17685 0.753 rs10245584 chr7:75745866 C/T cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7903847 0.642 rs11812223 chr10:99158455 T/C cg08345082 chr10:99160200 RRP12 -0.4 -6.63 -0.34 1.3100000000000001e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs2749592 0.550 rs7917262 chr10:37874602 A/C cg25427524 chr10:38739819 LOC399744 0.57 10.29 0.49 7.98e-22 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs12477438 0.520 rs11692699 chr2:99730657 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 13.94 0.6 2.84e-35 Chronic sinus infection; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg19425114 chr11:58907379 NA 0.39 6.2 0.32 1.62e-9 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC trans rs7618501 0.633 rs4688689 chr3:50035542 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.54 8.65 0.42 2.02e-16 Intelligence (multi-trait analysis); LIHC trans rs3780486 0.541 rs10738909 chr9:33148834 T/C cg20290983 chr6:43655470 MRPS18A 0.84 15.53 0.64 1.61e-41 IgG glycosylation; LIHC cis rs240764 0.579 rs240151 chr6:101067720 A/T cg09795085 chr6:101329169 ASCC3 0.44 6.38 0.33 5.77e-10 Neuroticism; LIHC cis rs4742903 1.000 rs7350148 chr9:106883085 T/G cg14250997 chr9:106856677 SMC2 0.41 7.46 0.37 7.11e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs3812831 0.654 rs367312 chr13:114930195 G/A cg08824895 chr13:115047677 UPF3A 0.41 5.77 0.3 1.78e-8 Schizophrenia; LIHC cis rs6543140 0.601 rs7558013 chr2:102992806 G/T cg09003973 chr2:102972529 NA 0.84 8.56 0.42 4.02e-16 Blood protein levels; LIHC cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.68 0.34 9.86e-11 Bipolar disorder; LIHC cis rs1577917 0.655 rs12203963 chr6:86223316 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.35 6.25 0.32 1.2e-9 Response to antipsychotic treatment; LIHC cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.11 0.31 2.79e-9 Menopause (age at onset); LIHC trans rs4843747 0.671 rs4072871 chr16:88106614 C/T cg26811252 chr16:29126840 RRN3P2 0.42 6.86 0.35 3.3e-11 Menopause (age at onset); LIHC cis rs3020736 0.500 rs8143153 chr22:42515637 G/C cg04733989 chr22:42467013 NAGA -0.65 -9.37 -0.45 1e-18 Autism spectrum disorder or schizophrenia; LIHC cis rs2576037 0.623 rs2576040 chr18:44582027 A/G cg19077165 chr18:44547161 KATNAL2 0.48 7.22 0.36 3.35e-12 Personality dimensions; LIHC cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.8e-30 Menopause (age at onset); LIHC cis rs7523273 0.925 rs12749612 chr1:208006749 A/G cg22525895 chr1:207977042 MIR29B2 -0.69 -10.27 -0.49 9.92e-22 Schizophrenia; LIHC cis rs6912958 0.559 rs395358 chr6:88057924 T/C cg08069147 chr6:88032118 GJB7;C6orf162 0.59 11.11 0.51 1.12e-24 Monocyte percentage of white cells; LIHC cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg02290350 chr8:58132656 NA 0.42 8.77 0.43 8.31e-17 Developmental language disorder (linguistic errors); LIHC cis rs12701220 0.895 rs12534778 chr7:1065861 C/T cg26769984 chr7:1090371 C7orf50 -0.61 -7.77 -0.39 9.03e-14 Bronchopulmonary dysplasia; LIHC cis rs4555082 0.872 rs7153832 chr14:105730563 G/T cg06808227 chr14:105710500 BRF1 -0.56 -7.49 -0.38 5.82e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs7224685 0.501 rs781848 chr17:3958105 A/C cg09597638 chr17:3907349 NA 0.6 10.71 0.5 2.78e-23 Type 2 diabetes; LIHC trans rs1814175 0.615 rs10839378 chr11:49806943 C/T cg15704280 chr7:45808275 SEPT13 -0.96 -19.81 -0.73 1.06e-58 Height; LIHC cis rs7223966 1.000 rs8075257 chr17:61728750 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.78 0.34 5.36e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs253664 0.897 rs1199336 chr3:138088221 T/A cg25188949 chr3:137893707 DBR1 -0.57 -5.88 -0.3 9.83e-9 Body mass index; LIHC cis rs1577917 0.629 rs7761762 chr6:86205968 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.55 10.61 0.5 6.38e-23 Response to antipsychotic treatment; LIHC cis rs2288073 0.965 rs13387930 chr2:24414400 A/G cg06627628 chr2:24431161 ITSN2 -0.6 -8.11 -0.4 9.46e-15 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg10755058 chr3:40428713 ENTPD3 0.4 6.88 0.35 2.79e-11 Renal cell carcinoma; LIHC cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg09417038 chr21:47716443 C21orf57 -0.51 -7.74 -0.39 1.1e-13 Testicular germ cell tumor; LIHC cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9811920 0.569 rs793445 chr3:99576644 T/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.89 0.35 2.75e-11 Axial length; LIHC cis rs7095607 0.606 rs4746738 chr10:69959837 C/T cg18986048 chr10:69913749 MYPN 0.39 5.86 0.3 1.09e-8 Lung function (FVC); LIHC trans rs7618501 1.000 rs9855505 chr3:49792158 T/G cg21659725 chr3:3221576 CRBN -0.99 -19.67 -0.73 3.83e-58 Intelligence (multi-trait analysis); LIHC cis rs10911363 0.592 rs2702178 chr1:183452545 G/A cg09173681 chr1:183549694 NCF2 0.54 9.51 0.46 3.46e-19 Systemic lupus erythematosus; LIHC cis rs7223966 1.000 rs3817181 chr17:61776538 G/C cg05941027 chr17:61774174 LIMD2 0.34 6.93 0.35 2.09e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2439831 0.867 rs3213990 chr15:43670226 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.9 16.82 0.67 1.11e-46 Lung cancer in ever smokers; LIHC cis rs2274273 0.870 rs10139083 chr14:55782735 C/A cg01864836 chr14:55583639 NA -0.37 -6.63 -0.34 1.34e-10 Protein biomarker; LIHC cis rs9814567 0.964 rs1534028 chr3:134284639 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs896854 0.818 rs896855 chr8:95959808 A/G cg16049864 chr8:95962084 TP53INP1 -0.61 -11.89 -0.54 1.65e-27 Type 2 diabetes; LIHC trans rs6951245 0.678 rs28600085 chr7:1169636 C/T cg13565492 chr6:43139072 SRF -0.78 -6.63 -0.34 1.28e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg21724239 chr8:58056113 NA 0.57 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.697 rs28655325 chr4:120372999 A/G cg09307838 chr4:120376055 NA 0.77 11.94 0.54 1.02e-27 Corneal astigmatism; LIHC cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg00684032 chr4:1343700 KIAA1530 0.4 6.77 0.34 5.54e-11 Obesity-related traits; LIHC cis rs6964587 1.000 rs2285333 chr7:91667692 T/G cg17063962 chr7:91808500 NA 1.02 19.65 0.73 4.62e-58 Breast cancer; LIHC cis rs8044995 0.563 rs3785127 chr16:68399590 C/G cg05110241 chr16:68378359 PRMT7 -0.85 -9.58 -0.46 2.07e-19 Schizophrenia; LIHC cis rs1005277 0.579 rs9299760 chr10:38377920 C/T cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs4820294 1.000 rs732856 chr22:38060691 C/G cg00142150 chr22:38071001 LGALS1 -0.71 -11.61 -0.53 1.69e-26 Fat distribution (HIV); LIHC cis rs11190604 1.000 rs11190604 chr10:102302457 A/G cg07080220 chr10:102295463 HIF1AN 0.54 7.58 0.38 3.32e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2228479 0.850 rs17232910 chr16:89839766 G/C cg06558623 chr16:89946397 TCF25 0.85 11.77 0.54 4.35e-27 Skin colour saturation; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg06873352 chr17:61820015 STRADA 0.75 13.24 0.58 1.32e-32 Prudent dietary pattern; LIHC cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg17971929 chr21:40555470 PSMG1 0.81 9.67 0.46 1.06e-19 Cognitive function; LIHC cis rs9911578 1.000 rs4793952 chr17:56608465 C/T cg12560992 chr17:57184187 TRIM37 -0.98 -17.86 -0.69 7.05e-51 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.684 rs2363279 chr7:1096143 A/G cg16145915 chr7:1198662 ZFAND2A -0.35 -8.52 -0.42 5.09e-16 Longevity;Endometriosis; LIHC cis rs7582720 1.000 rs4510208 chr2:203734866 C/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.46e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1008375 0.931 rs10939734 chr4:17570709 C/T cg02297831 chr4:17616191 MED28 0.47 6.89 0.35 2.66e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs921968 0.565 rs7580147 chr2:219643036 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.45 -0.33 3.85e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs9549367 0.789 rs8001506 chr13:113867153 A/C cg00898013 chr13:113819073 PROZ -0.34 -6.13 -0.31 2.44e-9 Platelet distribution width; LIHC cis rs903552 1.000 rs4965386 chr15:102003207 G/A cg25677261 chr15:102009856 PCSK6 -0.45 -6.23 -0.32 1.35e-9 Diabetic kidney disease; LIHC cis rs7618501 1.000 rs34614773 chr3:49753003 T/G cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs831571 0.636 rs56228642 chr3:64075759 T/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.54 -6.24 -0.32 1.26e-9 Type 2 diabetes; LIHC cis rs4803468 1.000 rs55986560 chr19:41939835 C/T cg14132834 chr19:41945861 ATP5SL 0.45 6.5 0.33 2.89e-10 Height; LIHC cis rs7474896 0.616 rs1985260 chr10:38434090 C/T cg25427524 chr10:38739819 LOC399744 -0.49 -6.31 -0.32 8.85e-10 Obesity (extreme); LIHC cis rs2274273 0.870 rs10147434 chr14:55674847 C/T cg04306507 chr14:55594613 LGALS3 0.34 6.41 0.33 4.77e-10 Protein biomarker; LIHC cis rs2404602 0.647 rs55778276 chr15:77136590 T/A cg23625390 chr15:77176239 SCAPER -0.54 -8.93 -0.43 2.66e-17 Blood metabolite levels; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg09033563 chr22:24373618 LOC391322 -0.49 -7.0 -0.35 1.33e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs801193 0.548 rs2109297 chr7:66122384 G/A cg18252515 chr7:66147081 NA 0.47 6.94 0.35 1.94e-11 Aortic root size; LIHC cis rs10927875 0.526 rs35340817 chr1:16178917 T/C cg21385522 chr1:16154831 NA -1.06 -11.77 -0.54 4.58e-27 Dilated cardiomyopathy; LIHC trans rs4604234 0.803 rs73463518 chr6:80976017 G/A cg08069338 chr6:160207898 SNORA29;TCP1 0.63 6.09 0.31 3.04e-9 Cancer; LIHC cis rs7224314 1.000 rs7226214 chr17:65383323 C/T cg01507342 chr17:65387096 PITPNC1 -0.47 -5.95 -0.31 6.74e-9 Diisocyanate-induced asthma; LIHC cis rs2304069 0.545 rs7728248 chr5:149394965 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.58 8.26 0.41 3.31e-15 HIV-1 control; LIHC cis rs3762637 1.000 rs9968189 chr3:122175136 G/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg20295408 chr7:1910781 MAD1L1 -0.52 -7.71 -0.38 1.35e-13 Bipolar disorder and schizophrenia; LIHC cis rs4718428 1.000 rs12534637 chr7:66327654 G/C cg18252515 chr7:66147081 NA -0.47 -6.04 -0.31 4.06e-9 Corneal structure; LIHC cis rs12479064 0.671 rs4851207 chr2:100105775 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.62 -7.67 -0.38 1.81e-13 Chronic sinus infection; LIHC trans rs1005277 0.579 rs1740749 chr10:38521646 A/G cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs941408 0.928 rs2741991 chr19:2802092 T/C cg02580895 chr19:2754563 NA -0.41 -6.1 -0.31 2.91e-9 Total cholesterol levels; LIHC cis rs72627509 0.857 rs2227901 chr4:57798189 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.57 8.33 0.41 1.98e-15 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs6933660 0.760 rs6904364 chr6:151754273 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.47 -7.12 -0.36 6.36e-12 Menarche (age at onset); LIHC cis rs17401966 0.838 rs9332414 chr1:10326963 C/T cg15208524 chr1:10270712 KIF1B 0.41 6.17 0.32 1.89e-9 Hepatocellular carcinoma; LIHC cis rs4891159 0.790 rs59762437 chr18:74153146 G/A cg24786174 chr18:74118243 ZNF516 -0.73 -13.0 -0.58 1.12e-31 Longevity; LIHC cis rs6840360 0.550 rs7689266 chr4:152561048 T/C cg22705602 chr4:152727874 NA -0.32 -6.26 -0.32 1.14e-9 Intelligence (multi-trait analysis); LIHC cis rs597539 0.652 rs668576 chr11:68668208 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.03 0.51 2.13e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9596863 1.000 rs9568946 chr13:54430220 T/C ch.13.53330881F chr13:54432880 NA 0.45 6.0 0.31 5.16e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs4728302 0.838 rs10225454 chr7:133591535 G/C cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs1552244 0.515 rs7613004 chr3:9999913 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -7.82 -0.39 6.59e-14 Alzheimer's disease; LIHC cis rs7909074 0.509 rs2183994 chr10:45389940 T/C cg05187965 chr10:45406764 TMEM72 -0.26 -6.34 -0.32 7.38e-10 Mean corpuscular volume; LIHC cis rs10193935 0.901 rs62142561 chr2:42477808 G/C cg27598129 chr2:42591480 NA -0.72 -10.54 -0.5 1.14e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs16828019 0.852 rs3904243 chr1:41574852 T/G cg03387723 chr1:41708464 SCMH1 -0.42 -6.93 -0.35 2.07e-11 Intelligence (multi-trait analysis); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg09301471 chr16:89349945 ANKRD11 0.42 6.28 0.32 1.04e-9 Alopecia areata; LIHC cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg08645402 chr16:4508243 NA 0.41 7.81 0.39 7.14e-14 Schizophrenia; LIHC cis rs9457247 0.534 rs9366078 chr6:167399512 A/G cg12798992 chr6:167411361 FGFR1OP -0.5 -8.13 -0.4 7.71e-15 Crohn's disease; LIHC cis rs2274273 0.624 rs11158034 chr14:55753560 C/T cg01864836 chr14:55583639 NA -0.36 -5.95 -0.31 6.6e-9 Protein biomarker; LIHC cis rs6066825 0.605 rs761273 chr20:47315488 A/G cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.76e-12 Colorectal cancer; LIHC cis rs3096299 0.685 rs4785571 chr16:89565169 A/G cg06640241 chr16:89574553 SPG7 0.7 13.17 0.58 2.51e-32 Multiple myeloma (IgH translocation); LIHC cis rs35306767 0.714 rs12777800 chr10:1070361 G/A cg26597838 chr10:835615 NA 0.78 7.54 0.38 4.23e-13 Eosinophil percentage of granulocytes; LIHC cis rs9790314 0.967 rs463928 chr3:161087734 A/T cg03342759 chr3:160939853 NMD3 -0.65 -7.71 -0.38 1.38e-13 Morning vs. evening chronotype; LIHC cis rs12477438 0.798 rs4850894 chr2:99629396 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.84 -0.65 9.44e-43 Chronic sinus infection; LIHC cis rs9914988 0.943 rs7215000 chr17:27088436 C/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.96 -0.35 1.79e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs17384381 1.000 rs79695640 chr1:85836073 T/C cg16011679 chr1:85725395 C1orf52 0.81 8.22 0.41 4.39e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs7615952 0.515 rs4441610 chr3:125681307 C/G cg05084668 chr3:125655381 ALG1L -0.56 -8.74 -0.43 1.09e-16 Blood pressure (smoking interaction); LIHC cis rs9513627 1.000 rs2390278 chr13:100159712 G/A cg25919922 chr13:100150906 NA 0.74 6.93 0.35 2.07e-11 Obesity-related traits; LIHC cis rs270601 0.955 rs273911 chr5:131661526 C/G cg24060327 chr5:131705240 SLC22A5 -0.82 -12.88 -0.57 3.09e-31 Acylcarnitine levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16868751 chr10:96162146 TBC1D12 0.42 6.38 0.33 5.76e-10 Pancreatic cancer; LIHC cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg00149659 chr3:10157352 C3orf10 -0.7 -7.26 -0.37 2.69e-12 Alzheimer's disease; LIHC cis rs7894051 0.717 rs4838741 chr10:135206873 C/T cg05676341 chr10:135206831 MTG1 0.88 8.65 0.42 2.09e-16 Lifespan; LIHC cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg18230493 chr5:56204884 C5orf35 -0.46 -6.17 -0.32 1.92e-9 Initial pursuit acceleration; LIHC cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg13047869 chr3:10149882 C3orf24 0.5 6.43 0.33 4.4e-10 Alzheimer's disease; LIHC trans rs561341 1.000 rs510264 chr17:30323414 A/G cg20587970 chr11:113659929 NA -1.47 -12.07 -0.55 3.44e-28 Hip circumference adjusted for BMI; LIHC cis rs62380364 0.602 rs650702 chr5:88055313 G/A cg22951263 chr5:87985283 NA -0.4 -6.85 -0.35 3.42e-11 Intelligence (multi-trait analysis); LIHC cis rs116095464 0.558 rs9688045 chr5:254035 T/C cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs9381040 0.655 rs2268188 chr6:41042590 T/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.3 -0.32 9.3e-10 Alzheimer's disease (late onset); LIHC cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.85e-26 Platelet count; LIHC cis rs10216189 0.785 rs4623325 chr7:5526807 C/T cg05318486 chr7:5553423 FBXL18 0.41 5.79 0.3 1.58e-8 Relative hand skill in reading disability; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg07677032 chr17:61819896 STRADA 0.42 6.15 0.32 2.18e-9 Prudent dietary pattern; LIHC cis rs2439831 0.681 rs3742969 chr15:43621947 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.91 17.62 0.69 6.95e-50 Lung cancer in ever smokers; LIHC cis rs7829975 0.688 rs7827182 chr8:8380471 C/G cg14343924 chr8:8086146 FLJ10661 0.42 5.91 0.3 8.38e-9 Mood instability; LIHC cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg21951975 chr1:209979733 IRF6 0.41 6.72 0.34 7.79e-11 Cleft lip with or without cleft palate; LIHC cis rs9399135 0.660 rs9389248 chr6:135282656 T/C cg24558204 chr6:135376177 HBS1L 0.4 6.63 0.34 1.32e-10 Red blood cell count; LIHC cis rs611744 0.967 rs610452 chr8:109188263 T/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs1538970 0.924 rs12046816 chr1:45891543 G/T cg05343316 chr1:45956843 TESK2 0.57 8.29 0.41 2.7e-15 Platelet count; LIHC trans rs3749237 1.000 rs3749237 chr3:49770032 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.64 10.03 0.48 6.42e-21 Resting heart rate; LIHC cis rs763121 0.925 rs4821815 chr22:39105707 G/A cg14440974 chr22:39074834 NA -0.37 -6.2 -0.32 1.59e-9 Menopause (age at onset); LIHC cis rs9612 1.000 rs16976747 chr19:44238152 G/A cg08581076 chr19:44259116 C19orf61 0.61 7.15 0.36 5.16e-12 Exhaled nitric oxide output; LIHC cis rs7772486 0.875 rs9390372 chr6:146363638 G/C cg13319975 chr6:146136371 FBXO30 -0.34 -5.74 -0.3 2.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs208520 0.690 rs12209753 chr6:66703951 A/G cg07460842 chr6:66804631 NA 0.74 8.61 0.42 2.8e-16 Exhaled nitric oxide output; LIHC cis rs8067545 0.586 rs2526478 chr17:20130452 A/G cg13482628 chr17:19912719 NA 0.43 7.05 0.36 1e-11 Schizophrenia; LIHC cis rs9325144 0.541 rs7303395 chr12:38664124 C/T cg26384229 chr12:38710491 ALG10B -0.59 -8.07 -0.4 1.19e-14 Morning vs. evening chronotype; LIHC cis rs1801251 0.964 rs13007783 chr2:233566679 G/A cg25237894 chr2:233734115 C2orf82 0.56 10.93 0.51 4.67e-24 Coronary artery disease; LIHC cis rs1577917 0.916 rs7759727 chr6:86518878 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.37 -0.41 1.47e-15 Response to antipsychotic treatment; LIHC cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs11098499 0.863 rs58452170 chr4:120459674 A/T cg09307838 chr4:120376055 NA 0.76 11.53 0.53 3.24e-26 Corneal astigmatism; LIHC cis rs9467773 1.000 rs9986382 chr6:26550619 T/C cg09904177 chr6:26538194 HMGN4 0.65 13.76 0.6 1.3600000000000001e-34 Intelligence (multi-trait analysis); LIHC cis rs7095607 0.560 rs2255381 chr10:69923535 C/T cg18986048 chr10:69913749 MYPN 0.47 7.12 0.36 6.47e-12 Lung function (FVC); LIHC cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg24549020 chr5:56110836 MAP3K1 0.5 6.49 0.33 3.09e-10 Initial pursuit acceleration; LIHC cis rs17253792 0.822 rs8013831 chr14:56172898 G/A cg01858014 chr14:56050164 KTN1 -0.63 -6.99 -0.35 1.42e-11 Putamen volume; LIHC cis rs7818688 0.697 rs58282276 chr8:95985391 G/A cg16049864 chr8:95962084 TP53INP1 0.6 6.51 0.33 2.69e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6952808 0.929 rs12699483 chr7:1975624 C/G cg21782813 chr7:2030301 MAD1L1 0.47 8.15 0.4 6.92e-15 Bipolar disorder and schizophrenia; LIHC cis rs763121 0.853 rs5750671 chr22:39094619 A/C cg21395723 chr22:39101663 GTPBP1 0.4 6.67 0.34 1.04e-10 Menopause (age at onset); LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg13126279 chr21:47581558 C21orf56 -0.46 -7.64 -0.38 2.19e-13 Testicular germ cell tumor; LIHC cis rs61612642 0.523 rs59004693 chr6:42157392 G/A cg01092361 chr6:42185687 MRPS10 0.88 9.05 0.44 1.12e-17 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs12477438 0.798 rs6740267 chr2:99561867 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.08 -14.97 -0.63 2.54e-39 Chronic sinus infection; LIHC cis rs6964587 1.000 rs28927678 chr7:91715662 C/T cg17063962 chr7:91808500 NA 1.01 19.11 0.72 6.41e-56 Breast cancer; LIHC cis rs4453791 1.000 rs11927309 chr3:38935115 C/T cg02254461 chr3:39195904 CSRNP1 0.65 5.84 0.3 1.23e-8 Social communication problems; LIHC cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg18876405 chr7:65276391 NA 0.56 9.39 0.45 9.02e-19 Aortic root size; LIHC cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg18357526 chr6:26021779 HIST1H4A 0.42 6.39 0.33 5.56e-10 Height; LIHC cis rs1062177 0.774 rs2964574 chr5:151155711 G/A cg00977110 chr5:151150581 G3BP1 0.54 6.96 0.35 1.79e-11 Preschool internalizing problems; LIHC trans rs2727020 0.533 rs10839195 chr11:48973460 C/T cg03929089 chr4:120376271 NA -0.44 -6.61 -0.34 1.49e-10 Coronary artery disease; LIHC cis rs5753037 0.585 rs36572 chr22:30200936 T/C cg01021169 chr22:30184971 ASCC2 -0.43 -8.54 -0.42 4.54e-16 Type 1 diabetes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25858983 chr17:42295711 UBTF 0.48 6.92 0.35 2.23e-11 Lung function (FEV1/FVC); LIHC cis rs7847628 0.765 rs10985024 chr9:123516812 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.59 8.76 0.43 9.43e-17 Birth weight; LIHC cis rs2274273 0.870 rs8021583 chr14:55749607 G/A cg01864836 chr14:55583639 NA -0.39 -6.95 -0.35 1.8e-11 Protein biomarker; LIHC cis rs2842992 0.789 rs10945635 chr6:160214487 C/A cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.93 0.43 2.7e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs116095464 0.558 rs56298907 chr5:283280 C/A cg22857025 chr5:266934 NA -1.52 -15.89 -0.65 5.89e-43 Breast cancer; LIHC cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg07308232 chr7:1071921 C7orf50 -0.56 -8.98 -0.44 1.83e-17 Longevity;Endometriosis; LIHC cis rs10504073 0.584 rs60449482 chr8:49974865 G/A cg00325661 chr8:49890786 NA 0.33 7.51 0.38 5.04e-13 Blood metabolite ratios; LIHC cis rs2749592 0.531 rs10764134 chr10:37856660 T/C cg25427524 chr10:38739819 LOC399744 0.55 10.02 0.48 6.7e-21 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs514406 0.679 rs960570 chr1:53237763 A/G cg08859206 chr1:53392774 SCP2 0.46 7.34 0.37 1.55e-12 Monocyte count; LIHC cis rs1670533 1.000 rs12645644 chr4:1054159 C/T cg27284194 chr4:1044797 NA 0.6 8.99 0.44 1.7e-17 Recombination rate (females); LIHC cis rs5769765 0.908 rs4074304 chr22:50309446 G/A cg02269571 chr22:50332266 NA -0.75 -9.95 -0.47 1.14e-20 Schizophrenia; LIHC cis rs2153535 0.580 rs7742794 chr6:8459723 C/A cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs7224737 1.000 rs9903204 chr17:40288062 G/A cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs8062405 0.655 rs7184597 chr16:28921809 T/C cg07451762 chr16:28383216 NA -0.35 -6.34 -0.32 7.31e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1577917 1.000 rs1857965 chr6:86630776 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs651907 0.535 rs34063583 chr3:101509948 C/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.83 -0.3 1.26e-8 Colorectal cancer; LIHC trans rs13113518 0.783 rs2171618 chr4:56430408 A/G cg15358633 chr12:38710606 ALG10B 0.43 6.25 0.32 1.21e-9 Height; LIHC cis rs2235642 0.533 rs2076436 chr16:1608082 A/G cg03034668 chr16:1723424 CRAMP1L -0.41 -6.35 -0.32 6.67e-10 Coronary artery disease; LIHC cis rs6570726 0.846 rs6570698 chr6:145918635 C/G cg23711669 chr6:146136114 FBXO30 0.61 10.5 0.49 1.53e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg19318889 chr4:1322082 MAEA 0.48 7.97 0.4 2.35e-14 Obesity-related traits; LIHC cis rs2032447 0.867 rs9295683 chr6:26069495 C/T cg18357526 chr6:26021779 HIST1H4A 0.84 11.91 0.54 1.31e-27 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.735 rs801188 chr5:140066916 G/T cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.56e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7716219 0.672 rs1396610 chr5:54878619 C/T cg14753740 chr5:54468940 CDC20B;MIR449C 0.43 5.9 0.3 8.93e-9 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26289012 chr17:3540036 CTNS;SHPK 0.45 6.11 0.31 2.74e-9 Lung function (FEV1/FVC); LIHC cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg00166722 chr3:10149974 C3orf24 0.48 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC trans rs7618501 0.633 rs4688689 chr3:50035542 C/T cg21659725 chr3:3221576 CRBN 0.66 10.66 0.5 4.37e-23 Intelligence (multi-trait analysis); LIHC cis rs1494950 1.000 rs7673375 chr4:14984117 G/T cg12377275 chr4:15005593 CPEB2 -0.79 -6.26 -0.32 1.15e-9 Political ideology; LIHC cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg11301795 chr4:187892539 NA -0.25 -6.61 -0.34 1.49e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 21.61 0.76 6.3e-66 Prudent dietary pattern; LIHC cis rs12048904 0.505 rs4517368 chr1:101255052 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.48 -7.6 -0.38 2.79e-13 Multiple sclerosis; LIHC cis rs7727544 0.684 rs2516788 chr5:131715565 G/C cg24060327 chr5:131705240 SLC22A5 0.6 8.63 0.42 2.38e-16 Blood metabolite levels; LIHC cis rs7131987 0.650 rs7301188 chr12:29455391 C/T cg14222432 chr12:29376421 FAR2 0.35 6.74 0.34 6.68e-11 QT interval; LIHC cis rs7917772 0.503 rs7896841 chr10:104294665 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9916302 0.904 rs12952384 chr17:37669536 T/C cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC cis rs6062302 0.545 rs2297430 chr20:62229244 T/C cg09650180 chr20:62225654 GMEB2 -0.38 -5.99 -0.31 5.21e-9 Glioblastoma; LIHC cis rs1949733 0.523 rs16842560 chr4:8544238 G/A cg11789530 chr4:8429930 ACOX3 -0.57 -7.92 -0.39 3.43e-14 Response to antineoplastic agents; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20591408 chr2:241516333 RNPEPL1 0.41 6.29 0.32 9.56e-10 Pancreatic cancer; LIHC cis rs7107174 1.000 rs2511168 chr11:77965081 T/G cg02023728 chr11:77925099 USP35 0.48 9.03 0.44 1.28e-17 Testicular germ cell tumor; LIHC cis rs4908768 0.539 rs1934138 chr1:8645816 G/A cg20416874 chr1:8611966 RERE -0.66 -12.78 -0.57 7.87e-31 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs17384381 1.000 rs12128907 chr1:85891385 A/G cg16011679 chr1:85725395 C1orf52 0.8 8.42 0.41 1.06e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs11696739 0.501 rs2243603 chr20:1546911 C/G cg15722679 chr20:1638393 SIRPG 0.48 8.76 0.43 9.14e-17 Mean platelet volume; LIHC cis rs2274273 0.805 rs28660594 chr14:55846174 T/C cg01864836 chr14:55583639 NA -0.38 -6.69 -0.34 9.03e-11 Protein biomarker; LIHC cis rs2832191 0.636 rs8131295 chr21:30516819 A/T cg24692254 chr21:30365293 RNF160 -0.43 -6.71 -0.34 7.91e-11 Dental caries; LIHC cis rs34779708 0.966 rs10827487 chr10:35406878 T/A cg04310649 chr10:35416472 CREM -0.45 -6.08 -0.31 3.17e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1799949 0.965 rs9897425 chr17:41430179 C/G cg05368731 chr17:41323189 NBR1 0.66 10.93 0.51 4.59e-24 Menopause (age at onset); LIHC cis rs72772090 0.710 rs17400741 chr5:96066576 C/G cg17330273 chr5:96107758 CAST;ERAP1 -0.65 -7.3 -0.37 2.05e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs35306767 0.761 rs11253558 chr10:1043983 T/C cg26597838 chr10:835615 NA 0.88 8.39 0.41 1.29e-15 Eosinophil percentage of granulocytes; LIHC cis rs55665837 0.961 rs12576926 chr11:14480292 C/T cg19336497 chr11:14380999 RRAS2 -0.45 -8.29 -0.41 2.53e-15 Vitamin D levels; LIHC cis rs709400 0.663 rs10141388 chr14:103939679 A/G cg26031613 chr14:104095156 KLC1 0.73 9.75 0.47 5.62e-20 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg27540799 chr1:2335599 RER1 -0.54 -7.71 -0.38 1.38e-13 Lung function (FEV1/FVC); LIHC cis rs1348850 0.914 rs4893944 chr2:178289357 G/T cg27490568 chr2:178487706 NA 0.36 5.72 0.3 2.33e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs732505 0.618 rs1337057 chr19:5676950 G/A cg26242866 chr19:5711310 LONP1 0.75 7.34 0.37 1.55e-12 vWF and FVIII levels; LIHC cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg18876405 chr7:65276391 NA 0.55 9.42 0.45 7.17e-19 Calcium levels; LIHC cis rs317689 0.690 rs618470 chr12:69672060 A/G cg14784868 chr12:69753453 YEATS4 0.55 7.91 0.39 3.67e-14 Response to diuretic therapy; LIHC cis rs12477438 0.666 rs10179910 chr2:99658503 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.67 -9.81 -0.47 3.56e-20 Chronic sinus infection; LIHC cis rs2404602 0.735 rs11857015 chr15:76649390 T/C cg23625390 chr15:77176239 SCAPER -0.48 -7.95 -0.39 2.75e-14 Blood metabolite levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12749787 chr12:12878379 APOLD1 -0.49 -6.31 -0.32 8.74e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1256061 0.646 rs1152588 chr14:64688175 G/C cg23250157 chr14:64679961 SYNE2 0.42 6.09 0.31 3.11e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.626 rs12423420 chr12:122938466 G/A cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.31 -0.37 1.86e-12 Body mass index; LIHC trans rs931812 0.825 rs6993937 chr8:101898707 A/G cg20993868 chr7:22813445 NA 0.37 9.42 0.45 6.86e-19 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs941873 0.772 rs7920127 chr10:81122914 T/C cg11057378 chr10:81107060 PPIF 0.37 5.99 0.31 5.18e-9 Height; LIHC cis rs8141529 0.778 rs5762795 chr22:29182500 C/A cg15103426 chr22:29168792 CCDC117 0.67 11.68 0.53 9.39e-27 Lymphocyte counts; LIHC trans rs17685 0.753 rs869806 chr7:75688623 C/T cg19862616 chr7:65841803 NCRNA00174 0.92 19.08 0.72 9.19e-56 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg08724919 chr11:61100443 DDB1;DAK -0.41 -6.05 -0.31 3.87e-9 Bipolar disorder; LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs7301016 0.846 rs12367878 chr12:63027483 C/T cg11441379 chr12:63026424 NA 0.6 6.21 0.32 1.53e-9 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27006547 chr11:62606509 WDR74 0.39 6.05 0.31 3.87e-9 Cognitive function; LIHC cis rs1355223 0.552 rs2421743 chr11:34882840 C/T cg11058730 chr11:34937778 PDHX;APIP 0.77 14.14 0.61 4.78e-36 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs459571 0.920 rs2520094 chr9:136919985 A/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.54 -8.23 -0.41 3.95e-15 Platelet distribution width; LIHC cis rs2153535 0.541 rs1414352 chr6:8485547 A/C cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs6500602 0.702 rs11076835 chr16:4549618 G/A cg08645402 chr16:4508243 NA 0.45 8.8 0.43 6.84e-17 Schizophrenia; LIHC cis rs6722750 0.846 rs13394665 chr2:64391431 A/C cg22352474 chr2:64371530 PELI1 -0.44 -6.51 -0.33 2.73e-10 Neuroticism; LIHC cis rs155076 0.666 rs9509640 chr13:21872880 T/C cg11317459 chr13:21872234 NA 1.32 14.5 0.62 1.74e-37 White matter hyperintensity burden; LIHC cis rs60871478 1.000 rs60871478 chr7:827325 A/G cg04727924 chr7:799746 HEATR2 -0.59 -8.78 -0.43 8.08e-17 Cerebrospinal P-tau181p levels; LIHC cis rs11122272 0.705 rs1416914 chr1:231533196 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.49 0.46 3.94e-19 Hemoglobin concentration; LIHC cis rs8180040 0.932 rs1531875 chr3:47452786 G/A cg16586182 chr3:47516702 SCAP -0.58 -11.18 -0.52 6.11e-25 Colorectal cancer; LIHC cis rs7572733 0.534 rs1435570 chr2:198731371 T/C cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC trans rs11088226 0.681 rs2833891 chr21:33928821 A/G cg09050820 chr6:167586206 TCP10L2 0.81 12.91 0.57 2.45e-31 Gastritis; LIHC cis rs508618 0.731 rs12033229 chr1:231545703 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.64 9.24 0.45 2.68e-18 Red blood cell count; LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg00091569 chr3:40428383 ENTPD3 0.39 6.57 0.33 1.91e-10 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg13409248 chr3:40428643 ENTPD3 0.41 6.77 0.34 5.65e-11 Renal cell carcinoma; LIHC cis rs600806 0.888 rs443345 chr1:109849254 A/G cg16275483 chr1:110013120 SYPL2 -0.5 -6.0 -0.31 4.93e-9 Intelligence (multi-trait analysis); LIHC trans rs3960554 0.808 rs78811105 chr7:75702795 G/A cg19862616 chr7:65841803 NCRNA00174 0.61 8.47 0.42 7.18e-16 Eotaxin levels; LIHC trans rs9388766 0.824 rs9375702 chr6:130384187 C/T cg03039519 chr14:93699218 NA -0.35 -6.31 -0.32 8.42e-10 Hip circumference adjusted for BMI; LIHC cis rs2455799 0.613 rs7614204 chr3:15792748 A/G cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs875971 0.929 rs778692 chr7:65872449 A/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs35110281 0.627 rs1436291 chr21:44965485 T/C cg21573476 chr21:45109991 RRP1B -0.52 -9.68 -0.46 9.26e-20 Mean corpuscular volume; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg15624725 chr16:30381887 TBC1D10B -0.41 -6.1 -0.31 2.9e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg21016266 chr12:122356598 WDR66 0.51 7.26 0.37 2.61e-12 Mean corpuscular volume; LIHC cis rs6500602 0.702 rs11645519 chr16:4538989 G/A cg08645402 chr16:4508243 NA 0.45 8.7 0.43 1.4e-16 Schizophrenia; LIHC cis rs1163251 0.837 rs2764886 chr1:120241771 C/T cg19096424 chr1:120255104 PHGDH 0.63 8.1 0.4 9.82e-15 Blood metabolite levels; LIHC cis rs2228479 0.850 rs17226519 chr16:89839854 T/C cg04013166 chr16:89971882 TCF25 0.52 6.62 0.34 1.35e-10 Skin colour saturation; LIHC cis rs12980942 1.000 rs12972266 chr19:41810771 G/A cg25627403 chr19:41769009 HNRNPUL1 0.57 6.86 0.35 3.22e-11 Coronary artery disease; LIHC cis rs796364 0.806 rs4673634 chr2:200863349 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 7.46 0.37 7e-13 Schizophrenia; LIHC cis rs35306767 0.903 rs1341741 chr10:888073 A/G cg20503657 chr10:835505 NA 1.02 12.21 0.55 1.02e-28 Eosinophil percentage of granulocytes; LIHC cis rs1568889 1.000 rs11826837 chr11:28322566 C/G cg06544937 chr11:28130018 METT5D1;KIF18A -0.51 -7.24 -0.36 2.95e-12 Bipolar disorder; LIHC cis rs11233413 1.000 rs7928570 chr11:82721526 A/C cg24227371 chr11:82718527 RAB30 -0.32 -7.07 -0.36 8.87e-12 Economic and political preferences (feminism/equality); LIHC cis rs7826238 0.623 rs2976893 chr8:8338219 G/T cg06636001 chr8:8085503 FLJ10661 -0.55 -8.2 -0.41 4.9e-15 Systolic blood pressure; LIHC cis rs5769765 0.913 rs28670284 chr22:50221973 C/T cg09182678 chr22:50328711 NA -0.49 -6.3 -0.32 9.02e-10 Schizophrenia; LIHC cis rs1023500 0.573 rs133378 chr22:42467695 G/C cg00645731 chr22:42541494 CYP2D7P1 0.39 6.23 0.32 1.37e-9 Schizophrenia; LIHC trans rs3780486 0.846 rs10971420 chr9:33125000 T/C cg04842962 chr6:43655489 MRPS18A 1.05 24.99 0.8 3.62e-79 IgG glycosylation; LIHC cis rs11758351 1.000 rs76329209 chr6:26196430 A/G cg03854865 chr6:26224070 HIST1H3E 0.63 7.07 0.36 8.82e-12 Gout;Renal underexcretion gout; LIHC cis rs7659604 0.502 rs13108419 chr4:122687238 A/G cg19671926 chr4:122722719 EXOSC9 0.55 8.34 0.41 1.91e-15 Type 2 diabetes; LIHC cis rs12079745 0.793 rs10919079 chr1:169133805 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.69 -6.74 -0.34 6.64e-11 QT interval; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg05148623 chr2:191513405 NAB1 -0.49 -6.8 -0.35 4.6e-11 Bilirubin levels; LIHC cis rs116095464 0.558 rs9312978 chr5:221930 C/G cg22496380 chr5:211416 CCDC127 -1.15 -10.21 -0.48 1.54e-21 Breast cancer; LIHC cis rs735396 0.595 rs2258287 chr12:121454313 G/T cg25281562 chr12:121454272 C12orf43 0.45 7.6 0.38 2.95e-13 N-glycan levels; LIHC cis rs11971779 0.648 rs9656512 chr7:139054046 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.13 0.48 2.85e-21 Diisocyanate-induced asthma; LIHC cis rs2463822 0.925 rs1528730 chr11:62081181 A/C cg06239285 chr11:62104954 ASRGL1 0.93 6.84 0.35 3.7e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs3736485 0.966 rs8028017 chr15:51912708 G/A cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.56e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11969893 0.850 rs9791284 chr6:101353886 G/A cg12253828 chr6:101329408 ASCC3 1.05 13.04 0.58 7.71e-32 Economic and political preferences (immigration/crime); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10678486 chr18:48494218 ELAC1 0.4 6.04 0.31 4.09e-9 Pancreatic cancer; LIHC cis rs13382862 0.895 rs2289082 chr2:20881958 A/T cg12334488 chr2:20871173 GDF7 0.42 8.58 0.42 3.4e-16 Abdominal aortic aneurysm; LIHC cis rs35110281 0.667 rs4819291 chr21:45123139 G/A cg04455712 chr21:45112962 RRP1B 0.49 8.54 0.42 4.39e-16 Mean corpuscular volume; LIHC cis rs9768139 0.733 rs13309363 chr7:158122179 C/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.82 -0.3 1.35e-8 Calcium levels; LIHC cis rs2625529 0.775 rs12913042 chr15:72202309 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.77 -0.3 1.73e-8 Red blood cell count; LIHC cis rs7312933 0.670 rs2406568 chr12:42552297 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.56 8.16 0.4 6.42e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs1005277 0.540 rs1814077 chr10:37992018 G/C cg27523141 chr10:43048294 ZNF37B 0.38 6.73 0.34 6.99e-11 Extrinsic epigenetic age acceleration; LIHC cis rs6430585 0.583 rs730005 chr2:136582694 T/C cg07305463 chr2:136567211 LCT -0.39 -5.74 -0.3 2.11e-8 Corneal structure; LIHC cis rs2228479 0.702 rs17233176 chr16:89832751 G/C cg19635926 chr16:89946313 TCF25 0.48 6.17 0.32 1.97e-9 Skin colour saturation; LIHC cis rs12220238 1.000 rs8255 chr10:75879750 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.99 0.35 1.43e-11 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg10220992 chr8:11324327 FAM167A -0.46 -6.16 -0.32 1.99e-9 Bilirubin levels; LIHC cis rs67311347 0.824 rs73073561 chr3:40357298 G/T cg13409248 chr3:40428643 ENTPD3 0.39 6.04 0.31 4.08e-9 Renal cell carcinoma; LIHC cis rs1144333 1.000 rs2202019 chr1:76299181 G/A cg03433033 chr1:76189801 ACADM 0.57 8.68 0.42 1.64e-16 Attention function in attention deficit hyperactive disorder; LIHC cis rs769267 0.930 rs3794993 chr19:19611550 G/T cg03709012 chr19:19516395 GATAD2A 1.0 17.82 0.69 1.03e-50 Tonsillectomy; LIHC cis rs12474201 0.862 rs7562173 chr2:46976217 C/G cg06386533 chr2:46925753 SOCS5 -0.61 -7.18 -0.36 4.39e-12 Height; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06341748 chr17:28951330 LRRC37B2 0.42 6.05 0.31 3.85e-9 Systolic blood pressure; LIHC cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg18357526 chr6:26021779 HIST1H4A 0.6 8.47 0.42 7.14e-16 Blood metabolite levels; LIHC cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg00149659 chr3:10157352 C3orf10 0.6 6.58 0.33 1.82e-10 Alzheimer's disease; LIHC cis rs66573146 0.831 rs67665838 chr4:7064870 G/A cg02503808 chr4:7069936 GRPEL1 -0.8 -8.65 -0.42 2.03e-16 Granulocyte percentage of myeloid white cells; LIHC cis rs2153535 0.580 rs5001130 chr6:8442298 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.66 0.42 1.91e-16 Motion sickness; LIHC cis rs1005277 0.579 rs2474594 chr10:38426661 G/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs7089973 0.604 rs765174 chr10:116601888 C/T cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9322817 0.583 rs10782363 chr6:105149713 C/G cg02098413 chr6:105308735 HACE1 0.42 8.13 0.4 7.83e-15 Thyroid stimulating hormone; LIHC cis rs36051895 0.632 rs10974983 chr9:5149657 G/T cg02405213 chr9:5042618 JAK2 -0.64 -11.08 -0.51 1.33e-24 Pediatric autoimmune diseases; LIHC cis rs11098499 0.909 rs11723839 chr4:120299673 G/A cg09307838 chr4:120376055 NA 0.75 11.44 0.53 7.26e-26 Corneal astigmatism; LIHC trans rs7618501 0.633 rs6772095 chr3:49978069 C/T cg21659725 chr3:3221576 CRBN 0.71 11.58 0.53 2.13e-26 Intelligence (multi-trait analysis); LIHC cis rs9420 0.961 rs10896647 chr11:57571883 C/T cg19752551 chr11:57585705 CTNND1 -0.51 -7.15 -0.36 5.18e-12 Schizophrenia; LIHC trans rs61931739 0.517 rs10844830 chr12:34308133 C/T cg26384229 chr12:38710491 ALG10B 0.48 6.66 0.34 1.08e-10 Morning vs. evening chronotype; LIHC cis rs35791980 0.534 rs1181904 chr7:76983314 A/G cg12876866 chr7:77025528 PION 0.46 6.72 0.34 7.51e-11 Pursuit maintenance gain; LIHC cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg00149659 chr3:10157352 C3orf10 0.68 7.2 0.36 3.97e-12 Alzheimer's disease; LIHC cis rs1198430 0.683 rs7551124 chr1:23785760 C/T cg13183780 chr1:23809682 ASAP3 -0.4 -6.77 -0.34 5.64e-11 Total cholesterol levels; LIHC trans rs116095464 0.764 rs10069197 chr5:230822 G/C cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs7122539 0.646 rs608248 chr11:66562248 C/T cg24851651 chr11:66362959 CCS -0.36 -6.31 -0.32 8.54e-10 HIV-1 susceptibility; LIHC cis rs6089584 0.924 rs6142906 chr20:60552554 G/C cg06108461 chr20:60628389 TAF4 -0.9 -14.01 -0.6 1.44e-35 Body mass index; LIHC trans rs3960554 0.741 rs28446604 chr7:75662518 C/T cg19862616 chr7:65841803 NCRNA00174 0.59 8.21 0.41 4.58e-15 Eotaxin levels; LIHC cis rs870825 0.860 rs28696121 chr4:185598743 G/A cg04058563 chr4:185651563 MLF1IP 0.78 6.95 0.35 1.83e-11 Blood protein levels; LIHC cis rs12477438 0.520 rs11123764 chr2:99750677 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.55 0.64 1.25e-41 Chronic sinus infection; LIHC cis rs9733 0.628 rs72700895 chr1:150626029 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg10360323 chr17:41437877 NA 0.4 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs4927850 0.918 rs4361313 chr3:195752260 A/G cg12923728 chr3:195709715 SDHAP1 -0.72 -10.12 -0.48 3.25e-21 Pancreatic cancer; LIHC cis rs5753618 0.539 rs8135344 chr22:31671932 G/T cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs9457247 0.902 rs34560498 chr6:167395862 A/G cg12798992 chr6:167411361 FGFR1OP 0.59 9.66 0.46 1.15e-19 Crohn's disease; LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs748404 0.697 rs572959 chr15:43550502 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.47 8.21 0.41 4.51e-15 Lung cancer; LIHC cis rs919433 0.963 rs4850428 chr2:198169772 G/A cg03934865 chr2:198174659 NA -0.56 -9.06 -0.44 1.01e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs13191362 0.688 rs73035006 chr6:162997083 G/T cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.92 0.3 7.85e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2239547 0.603 rs71301807 chr3:53085475 C/G cg11645453 chr3:52864694 ITIH4 0.27 6.53 0.33 2.36e-10 Schizophrenia; LIHC cis rs3749237 0.537 rs4459909 chr3:49469217 T/C cg02487422 chr3:49467188 NICN1 0.41 6.46 0.33 3.56e-10 Resting heart rate; LIHC cis rs7224737 1.000 rs8074708 chr17:40286354 A/G cg02450064 chr17:40260053 DHX58 0.29 6.01 0.31 4.65e-9 Fibrinogen levels; LIHC cis rs9649465 1.000 rs56396297 chr7:123350535 T/C cg03229431 chr7:123269106 ASB15 -0.37 -7.8 -0.39 7.37e-14 Migraine; LIHC cis rs16858210 0.618 rs12638094 chr3:183565559 G/A cg25686905 chr3:183603175 PARL -0.41 -5.95 -0.31 6.46e-9 Menopause (age at onset); LIHC cis rs9733 0.519 rs6700022 chr1:150670484 G/T cg17724175 chr1:150552817 MCL1 -0.48 -9.88 -0.47 2.09e-20 Tonsillectomy; LIHC cis rs2072499 0.833 rs2842870 chr1:156200671 T/C cg25208724 chr1:156163844 SLC25A44 0.6 10.42 0.49 2.91e-22 Testicular germ cell tumor; LIHC cis rs6570726 0.905 rs419575 chr6:145840174 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg07677032 chr17:61819896 STRADA 0.43 6.19 0.32 1.77e-9 Prudent dietary pattern; LIHC cis rs1461503 0.934 rs930983 chr11:122834414 A/G cg25161029 chr11:122845972 NA 0.38 6.3 0.32 9.37e-10 Menarche (age at onset); LIHC cis rs2625529 0.824 rs35112434 chr15:72448326 G/T cg16672083 chr15:72433130 SENP8 -0.3 -5.73 -0.3 2.18e-8 Red blood cell count; LIHC cis rs8141529 0.504 rs6005915 chr22:29233262 A/G cg02153584 chr22:29168773 CCDC117 0.51 7.62 0.38 2.58e-13 Lymphocyte counts; LIHC cis rs6754311 0.731 rs3769005 chr2:136603366 C/G cg17750252 chr2:136567154 LCT 0.33 6.09 0.31 3.12e-9 Mosquito bite size; LIHC cis rs3770081 1.000 rs17027011 chr2:86406556 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.89 -9.44 -0.45 5.87e-19 Facial emotion recognition (sad faces); LIHC cis rs6545883 0.895 rs796597 chr2:61681060 A/G cg15711740 chr2:61764176 XPO1 -0.42 -5.85 -0.3 1.13e-8 Tuberculosis; LIHC cis rs10751667 0.643 rs11246362 chr11:969818 C/T cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs7772486 0.776 rs4316025 chr6:146238032 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -6.06 -0.31 3.68e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2749592 0.513 rs1208708 chr10:38085576 A/G cg25427524 chr10:38739819 LOC399744 -0.64 -12.42 -0.56 1.6800000000000001e-29 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6782228 0.606 rs2712381 chr3:128338600 A/C cg16766828 chr3:128327626 NA -0.41 -6.46 -0.33 3.69e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs3617 0.573 rs62253583 chr3:52928334 G/A cg11645453 chr3:52864694 ITIH4 -0.22 -5.77 -0.3 1.78e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs9733 0.596 rs2275236 chr1:150669952 A/G cg15448220 chr1:150897856 SETDB1 -0.39 -6.08 -0.31 3.19e-9 Tonsillectomy; LIHC cis rs41271473 0.526 rs12094319 chr1:228717836 G/C cg10167378 chr1:228756711 NA 0.67 6.77 0.34 5.47e-11 Chronic lymphocytic leukemia; LIHC cis rs2842992 0.830 rs1535475 chr6:160148935 T/C cg16489826 chr6:160211363 TCP1;MRPL18 0.54 9.39 0.45 8.91e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs7216064 1.000 rs8079754 chr17:65887896 A/G cg12091567 chr17:66097778 LOC651250 -0.63 -8.73 -0.43 1.17e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.8 0.3 1.55e-8 Menopause (age at onset); LIHC cis rs9733 0.569 rs11204691 chr1:150644339 A/T cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs151997 0.962 rs152687 chr5:50208563 A/G cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs1577917 0.839 rs12664634 chr6:86579414 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.22 -0.36 3.34e-12 Response to antipsychotic treatment; LIHC cis rs6952808 0.929 rs2280546 chr7:1976863 G/A cg04267008 chr7:1944627 MAD1L1 -0.65 -10.38 -0.49 4e-22 Bipolar disorder and schizophrenia; LIHC cis rs6120849 0.707 rs6120798 chr20:33610822 T/G cg24642439 chr20:33292090 TP53INP2 0.65 7.0 0.35 1.36e-11 Protein C levels; LIHC cis rs60871478 0.947 rs62432866 chr7:809281 T/G cg13844804 chr7:814759 HEATR2 0.43 5.76 0.3 1.85e-8 Cerebrospinal P-tau181p levels; LIHC cis rs17376456 0.877 rs12109629 chr5:93359702 A/G cg25358565 chr5:93447407 FAM172A 1.1 10.04 0.48 5.77e-21 Diabetic retinopathy; LIHC cis rs3768617 0.510 rs2224933 chr1:183095765 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs2204008 0.715 rs11514282 chr12:38169056 G/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs6450176 0.597 rs1541682 chr5:53304401 C/T ch.5.1024479R chr5:53302184 ARL15 -0.98 -17.56 -0.69 1.15e-49 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs7249142 0.562 rs11085253 chr19:19277517 A/G cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.36 -5.86 -0.3 1.09e-8 IgG glycosylation; LIHC cis rs55665837 0.701 rs10160597 chr11:14603992 G/A cg19336497 chr11:14380999 RRAS2 -0.37 -6.18 -0.32 1.83e-9 Vitamin D levels; LIHC cis rs2282802 0.685 rs7737543 chr5:139646026 A/G cg26211634 chr5:139558579 C5orf32 0.39 6.02 0.31 4.57e-9 Intelligence (multi-trait analysis); LIHC cis rs1570884 0.536 rs1359541 chr13:50158939 A/G cg03651054 chr13:50194643 NA 0.38 6.83 0.35 4e-11 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs600231 0.665 rs12790095 chr11:65326086 T/G cg10628098 chr11:65292300 SCYL1 0.38 5.78 0.3 1.67e-8 Bone mineral density; LIHC cis rs28595532 0.748 rs67928655 chr4:119336525 C/A cg21605333 chr4:119757512 SEC24D 0.99 8.23 0.41 3.95e-15 Cannabis dependence symptom count; LIHC cis rs2075671 0.855 rs11974395 chr7:100282538 G/A cg20848291 chr7:100343083 ZAN -0.46 -6.53 -0.33 2.37e-10 Other erythrocyte phenotypes; LIHC cis rs9902453 0.934 rs7211246 chr17:28485762 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.04 0.44 1.23e-17 Coffee consumption (cups per day); LIHC cis rs9467773 0.844 rs2393669 chr6:26503873 C/T cg09904177 chr6:26538194 HMGN4 0.66 13.85 0.6 6.03e-35 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.791 rs2416797 chr9:123480600 C/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 7.95 0.39 2.83e-14 Hip circumference adjusted for BMI; LIHC cis rs7833986 0.501 rs2719258 chr8:56941389 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.73 7.65 0.38 2.03e-13 Height; LIHC trans rs2777491 0.915 rs16971767 chr15:41623308 T/C cg15257565 chr10:42644887 NA 0.31 6.07 0.31 3.35e-9 Ulcerative colitis; LIHC cis rs4629710 0.592 rs9492877 chr6:131562577 C/G cg12606694 chr6:131520996 AKAP7 0.62 7.26 0.37 2.62e-12 Multiple myeloma (IgH translocation); LIHC cis rs7903847 0.642 rs10882908 chr10:99134970 T/C cg08345082 chr10:99160200 RRP12 -0.37 -6.13 -0.31 2.37e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs600806 0.778 rs4970765 chr1:110009171 C/T cg02415029 chr1:110025642 ATXN7L2 -0.49 -6.31 -0.32 8.63e-10 Intelligence (multi-trait analysis); LIHC cis rs4979906 1.000 rs11813624 chr10:79453162 T/C cg07817648 chr10:79422355 NA -0.3 -6.34 -0.32 7.46e-10 Mortality in heart failure; LIHC cis rs2280018 0.963 rs11075255 chr16:15166232 A/G cg27102117 chr16:15229624 NA 0.28 6.0 0.31 5.01e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg06969265 chr17:73775802 H3F3B 0.48 6.05 0.31 3.82e-9 Psoriasis; LIHC cis rs72781680 0.898 rs72796154 chr2:23933839 G/A cg08917208 chr2:24149416 ATAD2B 0.97 8.25 0.41 3.56e-15 Lymphocyte counts; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg11494091 chr17:61959527 GH2 0.45 8.37 0.41 1.52e-15 Prudent dietary pattern; LIHC cis rs703842 0.616 rs4760171 chr12:58225904 A/G cg18357645 chr12:58087776 OS9 -0.42 -6.15 -0.32 2.13e-9 Multiple sclerosis; LIHC cis rs6466055 0.720 rs4730082 chr7:105027509 A/G cg04380332 chr7:105027541 SRPK2 -0.36 -6.73 -0.34 7.38e-11 Schizophrenia; LIHC cis rs2549003 1.000 rs2549005 chr5:131827191 C/T cg21138405 chr5:131827807 IRF1 0.31 7.18 0.36 4.3e-12 Asthma (sex interaction); LIHC cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg06238570 chr21:40685208 BRWD1 -0.51 -8.29 -0.41 2.53e-15 Cognitive function; LIHC cis rs853679 0.542 rs9393892 chr6:28081394 A/G cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC cis rs447735 0.587 rs258336 chr16:89720831 A/C cg04240660 chr16:89714849 CHMP1A -0.53 -9.08 -0.44 9.16e-18 Hemoglobin concentration; LIHC cis rs6942756 1.000 rs6971917 chr7:128976919 G/A cg02491457 chr7:128862824 NA -0.61 -8.9 -0.43 3.41e-17 White matter hyperintensity burden; LIHC cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg02475777 chr4:1388615 CRIPAK 0.4 6.11 0.31 2.78e-9 Longevity; LIHC cis rs4474465 0.688 rs4275650 chr11:78284822 T/A cg02023728 chr11:77925099 USP35 -0.34 -5.96 -0.31 6.13e-9 Alzheimer's disease (survival time); LIHC cis rs7959452 0.557 rs7980883 chr12:69778914 C/T cg20891283 chr12:69753455 YEATS4 0.9 19.55 0.73 1.18e-57 Blood protein levels; LIHC cis rs875971 0.830 rs427575 chr7:65519219 A/G cg11764359 chr7:65958608 NA 0.83 13.78 0.6 1.11e-34 Aortic root size; LIHC cis rs9733 0.596 rs6678013 chr1:150623285 T/G cg15448220 chr1:150897856 SETDB1 0.4 6.26 0.32 1.16e-9 Tonsillectomy; LIHC cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.53 8.48 0.42 7.02e-16 Schizophrenia; LIHC cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg26338869 chr17:61819248 STRADA 0.61 8.7 0.43 1.45e-16 Prudent dietary pattern; LIHC cis rs4654899 0.785 rs9426736 chr1:21505931 T/G cg08539965 chr1:21396338 EIF4G3 0.32 5.74 0.3 2.11e-8 Superior frontal gyrus grey matter volume; LIHC cis rs9611565 0.592 rs5758406 chr22:42076641 A/G cg06634786 chr22:41940651 POLR3H 0.6 6.6 0.34 1.59e-10 Vitiligo; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11688874 chr10:28822482 WAC 0.52 7.57 0.38 3.44e-13 Pancreatic cancer; LIHC cis rs61776719 0.875 rs10890238 chr1:38445654 A/T cg26398791 chr1:38455867 SF3A3 -0.45 -6.2 -0.32 1.67e-9 Coronary artery disease; LIHC cis rs9918079 0.560 rs4698402 chr4:15629803 G/A cg04067612 chr4:15429572 C1QTNF7 -0.27 -5.78 -0.3 1.7e-8 Obesity-related traits; LIHC cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg03264133 chr6:25882463 NA -0.54 -6.62 -0.34 1.43e-10 Intelligence (multi-trait analysis); LIHC trans rs877282 0.945 rs11253388 chr10:787852 A/G cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.75e-9 Menopause (age at onset); LIHC cis rs11112613 0.818 rs2374507 chr12:106009570 A/C cg03607813 chr12:105948248 NA 0.47 7.29 0.37 2.24e-12 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs13108904 0.604 rs11946375 chr4:1313488 T/C cg00684032 chr4:1343700 KIAA1530 0.42 6.87 0.35 2.99e-11 Obesity-related traits; LIHC cis rs13108904 0.539 rs13141992 chr4:1340765 C/T cg00684032 chr4:1343700 KIAA1530 0.59 8.51 0.42 5.51e-16 Obesity-related traits; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19257478 chr10:21806076 C10orf140 -0.44 -6.36 -0.33 6.32e-10 Pancreatic cancer; LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg11062466 chr8:58055876 NA 0.5 7.46 0.37 7.09e-13 Developmental language disorder (linguistic errors); LIHC cis rs9640161 0.750 rs11765644 chr7:150026339 C/G cg17279839 chr7:150038598 RARRES2 0.58 11.7 0.53 8.06e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs151997 1.000 rs27247 chr5:50232299 T/C cg06027927 chr5:50259733 NA -0.57 -7.71 -0.38 1.38e-13 Callous-unemotional behaviour; LIHC trans rs9914544 1.000 rs9916245 chr17:18766825 C/G cg04702396 chr17:15466718 FAM18B2 0.44 6.69 0.34 8.88e-11 Educational attainment (years of education); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14001871 chr13:113488290 ATP11A 0.44 6.58 0.34 1.81e-10 Longevity; LIHC cis rs7408868 1.000 rs7247906 chr19:15271135 T/G cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC cis rs2204008 0.774 rs8189620 chr12:38241621 A/G cg26384229 chr12:38710491 ALG10B 0.87 10.83 0.51 1.06e-23 Bladder cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08037420 chr3:172428855 NCEH1 0.44 6.42 0.33 4.5e-10 Pancreatic cancer; LIHC cis rs8072100 0.840 rs9895746 chr17:45479099 C/A cg25173405 chr17:45401733 C17orf57 -0.41 -5.71 -0.3 2.45e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs4144743 0.938 rs35439279 chr17:45321694 C/T cg18085866 chr17:45331354 ITGB3 -0.59 -8.6 -0.42 2.93e-16 Body mass index; LIHC cis rs2108225 0.967 rs7785790 chr7:107449896 C/T cg18560240 chr7:107437656 SLC26A3 0.38 5.83 0.3 1.3e-8 Ulcerative colitis; LIHC cis rs7772486 0.875 rs10457794 chr6:146415608 A/G cg23711669 chr6:146136114 FBXO30 0.65 10.91 0.51 5.7e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2832191 0.740 rs2832175 chr21:30475606 A/G cg24692254 chr21:30365293 RNF160 -0.88 -16.82 -0.67 1.12e-46 Dental caries; LIHC cis rs2439831 0.850 rs16963953 chr15:44081719 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.43 0.41 1.01e-15 Lung cancer in ever smokers; LIHC cis rs9457247 1.000 rs385863 chr6:167386615 C/G cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs826838 0.967 rs1352123 chr12:39130992 T/C cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs9527 0.615 rs17725614 chr10:104685493 G/C cg15744005 chr10:104629667 AS3MT -0.29 -5.82 -0.3 1.34e-8 Arsenic metabolism; LIHC cis rs9303401 0.614 rs68100606 chr17:56500898 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.91 12.25 0.55 7.33e-29 Cognitive test performance; LIHC cis rs11112613 0.550 rs73186004 chr12:106043512 A/C cg03607813 chr12:105948248 NA 0.42 6.6 0.34 1.54e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7264396 0.580 rs2064511 chr20:34448810 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.55 7.68 0.38 1.69e-13 Total cholesterol levels; LIHC cis rs9457247 1.000 rs2769347 chr6:167371737 T/A cg23791538 chr6:167370224 RNASET2 0.69 11.58 0.53 2.13e-26 Crohn's disease; LIHC cis rs13190036 1.000 rs4976682 chr5:176726002 A/G cg06532880 chr5:176731545 PRELID1;RAB24 -0.42 -5.81 -0.3 1.45e-8 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13009927 chr2:242254519 SEPT2;HDLBP 0.4 6.14 0.32 2.27e-9 Lung function (FEV1/FVC); LIHC cis rs734999 0.572 rs2985857 chr1:2532624 C/T cg18854424 chr1:2615690 NA -0.32 -7.08 -0.36 8.14e-12 Ulcerative colitis; LIHC cis rs655641 0.684 rs542167 chr11:85707228 A/G cg09030501 chr11:85779252 PICALM -0.53 -6.44 -0.33 4.11e-10 Platelet count; LIHC cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg05368731 chr17:41323189 NBR1 -0.63 -10.87 -0.51 7.89e-24 Menopause (age at onset); LIHC cis rs875971 0.660 rs3764903 chr7:66098482 G/A cg11764359 chr7:65958608 NA -0.7 -10.37 -0.49 4.31e-22 Aortic root size; LIHC cis rs8078723 0.966 rs57065891 chr17:38168227 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.56 -8.94 -0.44 2.44e-17 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs8078723 1.000 rs4795412 chr17:38150604 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.58 -9.29 -0.45 1.88e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs709400 0.628 rs2273699 chr14:103923475 A/G cg26031613 chr14:104095156 KLC1 0.72 9.62 0.46 1.55e-19 Body mass index; LIHC cis rs35306767 0.903 rs11253495 chr10:937064 C/T cg26597838 chr10:835615 NA 1.08 12.99 0.57 1.21e-31 Eosinophil percentage of granulocytes; LIHC cis rs2228479 0.850 rs17226666 chr16:89835401 G/A cg00800038 chr16:89945340 TCF25 -0.6 -8.93 -0.43 2.69e-17 Skin colour saturation; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.04 0.55 4.54e-28 Height; LIHC trans rs4942242 0.640 rs9533571 chr13:44230136 C/T cg19169023 chr15:41853346 TYRO3 -0.52 -7.36 -0.37 1.37e-12 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs769267 0.965 rs2269873 chr19:19392401 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.61 9.55 0.46 2.63e-19 Tonsillectomy; LIHC cis rs3781454 1 rs3781454 chr10:126348565 G/A cg20435097 chr10:126320824 FAM53B -0.67 -12.8 -0.57 6.4e-31 White blood cell count; LIHC cis rs875971 0.929 rs778712 chr7:65849978 C/T cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs7772486 0.790 rs3924499 chr6:146232978 A/T cg05347473 chr6:146136440 FBXO30 -0.38 -6.04 -0.31 4.04e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2727020 0.658 rs4980440 chr11:49386017 C/T cg03929089 chr4:120376271 NA -0.86 -16.27 -0.66 1.78e-44 Coronary artery disease; LIHC cis rs7666738 0.830 rs34070283 chr4:98893027 A/T cg05340658 chr4:99064831 C4orf37 0.66 11.9 0.54 1.49e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs1005277 0.541 rs2505193 chr10:38394638 G/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs599083 0.530 rs583545 chr11:68178635 T/C cg16797656 chr11:68205561 LRP5 -0.49 -7.7 -0.38 1.43e-13 Bone mineral density (spine); LIHC trans rs6058796 1.000 rs6141779 chr20:31259366 C/T cg02600331 chr11:130417168 NA 0.36 7.75 0.39 1.03e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs904251 0.861 rs1757169 chr6:37487076 G/T cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.39e-12 Cognitive performance; LIHC cis rs7129556 0.520 rs6592730 chr11:77274203 T/C cg03570279 chr11:77446074 RSF1 -0.36 -6.68 -0.34 9.43e-11 Weight loss (gastric bypass surgery); LIHC cis rs1568889 0.838 rs11030265 chr11:28296168 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.23 0.61 2.02e-36 Bipolar disorder; LIHC cis rs9309711 0.643 rs4264589 chr2:3481098 G/T cg10845886 chr2:3471009 TTC15 -0.44 -8.17 -0.4 5.96e-15 Neurofibrillary tangles; LIHC cis rs3806843 0.619 rs2569160 chr5:140028774 T/C cg16179182 chr5:140090404 VTRNA1-1 0.37 6.16 0.32 2.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2857078 0.745 rs4793085 chr17:42320732 A/C cg10896456 chr17:42255109 ASB16;C17orf65 -0.42 -7.29 -0.37 2.21e-12 Red cell distribution width;Reticulocyte count; LIHC cis rs1003719 0.715 rs8129942 chr21:38552070 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -11.03 -0.51 2.07e-24 Eye color traits; LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg25894440 chr7:65020034 NA 0.4 6.23 0.32 1.38e-9 Calcium levels; LIHC cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg00166722 chr3:10149974 C3orf24 0.52 6.28 0.32 1.03e-9 Alzheimer's disease; LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.48 11.15 0.52 7.52e-25 Calcium levels; LIHC cis rs10883723 0.810 rs2281879 chr10:104268877 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.16 0.58 2.72e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4845570 1.000 rs3790514 chr1:151744168 T/C cg07092448 chr1:151763213 TDRKH -0.73 -7.93 -0.39 3.06e-14 Coronary artery disease; LIHC cis rs1008375 0.966 rs3796813 chr4:17591648 A/G cg02297831 chr4:17616191 MED28 0.46 7.1 0.36 7.04e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg11062466 chr8:58055876 NA 0.5 7.42 0.37 9.56e-13 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.964 rs55748098 chr7:65763618 T/C cg11764359 chr7:65958608 NA -0.91 -16.9 -0.67 5.28e-47 Aortic root size; LIHC cis rs67981189 0.593 rs221915 chr14:71592142 G/A cg15816911 chr14:71606274 NA -0.44 -7.03 -0.36 1.12e-11 Schizophrenia; LIHC cis rs10503871 0.526 rs35370135 chr8:30489769 A/G cg26383811 chr8:30366931 RBPMS 0.42 6.47 0.33 3.37e-10 Metabolite levels (X-11787); LIHC cis rs922107 0.641 rs11580069 chr1:89981376 T/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.52 -0.38 4.77e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs751728 0.965 rs4713681 chr6:33754817 T/C cg25922239 chr6:33757077 LEMD2 0.43 7.14 0.36 5.73e-12 Crohn's disease; LIHC cis rs6424115 1.000 rs2179395 chr1:24148365 T/C cg15997130 chr1:24165203 NA 0.45 9.22 0.45 3.03e-18 Immature fraction of reticulocytes; LIHC cis rs2842992 0.789 rs2277072 chr6:160182845 A/G cg11366901 chr6:160182831 ACAT2 0.94 16.17 0.66 4.53e-44 Age-related macular degeneration (geographic atrophy); LIHC trans rs1005277 0.540 rs2224248 chr10:38451886 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs254781 0.505 rs190438 chr5:88026902 C/T cg22951263 chr5:87985283 NA -0.38 -6.21 -0.32 1.54e-9 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs4974017 chr3:40473519 C/T cg13409248 chr3:40428643 ENTPD3 0.42 7.14 0.36 5.71e-12 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg00656387 chr3:40428638 ENTPD3 0.48 8.38 0.41 1.44e-15 Renal cell carcinoma; LIHC cis rs36051895 0.589 rs62543573 chr9:5201675 A/G cg02405213 chr9:5042618 JAK2 -0.64 -10.58 -0.5 8.14e-23 Pediatric autoimmune diseases; LIHC trans rs7618501 0.933 rs3811695 chr3:49761613 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs1355223 1.000 rs1355222 chr11:34758716 C/G cg11058730 chr11:34937778 PDHX;APIP -0.47 -6.43 -0.33 4.19e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6665290 0.901 rs11580229 chr1:227210820 G/A cg10327440 chr1:227177885 CDC42BPA -1.12 -22.19 -0.77 3.15e-68 Myeloid white cell count; LIHC cis rs2832191 0.716 rs1888439 chr21:30454457 A/G cg24692254 chr21:30365293 RNF160 0.86 15.45 0.64 3.35e-41 Dental caries; LIHC cis rs2012796 0.957 rs7151434 chr14:81819468 A/G cg02996355 chr14:81879375 NA 0.43 6.43 0.33 4.2e-10 Night sleep phenotypes; LIHC cis rs7216064 1.000 rs11079707 chr17:65835617 A/G cg12091567 chr17:66097778 LOC651250 0.58 8.18 0.4 5.6e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs11190604 0.767 rs10883489 chr10:102194532 T/C cg07080220 chr10:102295463 HIF1AN 0.48 7.03 0.36 1.11e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9513627 0.915 rs73556173 chr13:100121766 C/T cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs116095464 0.510 rs10057501 chr5:239545 T/C cg22496380 chr5:211416 CCDC127 -1.05 -10.87 -0.51 7.75e-24 Breast cancer; LIHC cis rs72627123 0.582 rs62005101 chr14:74500585 A/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.47 6.22 0.32 1.43e-9 Morning vs. evening chronotype; LIHC cis rs72627123 0.867 rs80298117 chr14:74447383 G/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.46 0.42 8.11e-16 Morning vs. evening chronotype; LIHC cis rs853679 0.517 rs1947863 chr6:28099344 G/A cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC trans rs208520 0.690 rs866452 chr6:66849936 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.31 -0.41 2.27e-15 Exhaled nitric oxide output; LIHC cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg02475777 chr4:1388615 CRIPAK 0.54 7.81 0.39 7.05e-14 Longevity; LIHC cis rs7131987 0.903 rs11050153 chr12:29405148 T/C cg16970926 chr12:29381810 FAR2 0.32 6.83 0.35 3.78e-11 QT interval; LIHC cis rs57221529 0.563 rs4957057 chr5:569230 C/G cg09021430 chr5:549028 NA -0.43 -8.88 -0.43 3.89e-17 Lung disease severity in cystic fibrosis; LIHC cis rs875971 1.000 rs1540651 chr7:65650121 C/T cg18876405 chr7:65276391 NA -0.38 -6.73 -0.34 7.21e-11 Aortic root size; LIHC cis rs11671005 0.735 rs11666716 chr19:58920952 A/G cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs12701220 0.553 rs9639882 chr7:1133731 G/A cg04498913 chr7:1135747 C7orf50 0.45 7.18 0.36 4.49e-12 Bronchopulmonary dysplasia; LIHC cis rs4795419 1 rs4795419 chr17:38166003 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.14 -0.44 5.58e-18 Monocyte percentage of white cells; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13671128 chr19:1612344 TCF3 0.42 6.21 0.32 1.56e-9 Longevity; LIHC cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.46 0.37 7.33e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs736408 0.677 rs2286798 chr3:52821177 G/T cg11645453 chr3:52864694 ITIH4 -0.22 -5.73 -0.3 2.22e-8 Bipolar disorder; LIHC cis rs3106136 0.681 rs7658390 chr4:95304083 C/T cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg11062466 chr8:58055876 NA 0.52 7.28 0.37 2.35e-12 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.855 rs490897 chr11:111487914 A/G cg22437258 chr11:111473054 SIK2 0.51 5.79 0.3 1.63e-8 Primary sclerosing cholangitis; LIHC cis rs4474465 0.920 rs10899535 chr11:78216237 G/A cg27205649 chr11:78285834 NARS2 0.38 5.88 0.3 9.7e-9 Alzheimer's disease (survival time); LIHC cis rs9902453 0.791 rs62068629 chr17:28187596 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.32 0.55 4.26e-29 Coffee consumption (cups per day); LIHC cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.49 -6.58 -0.34 1.8e-10 Bipolar disorder; LIHC cis rs12477438 0.715 rs6724476 chr2:99627316 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.65 -0.38 2.08e-13 Chronic sinus infection; LIHC cis rs1552244 0.882 rs13100734 chr3:10022878 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.71 9.7 0.46 8.25e-20 Alzheimer's disease; LIHC cis rs5769765 0.817 rs11912619 chr22:50317401 G/A cg26441486 chr22:50317300 CRELD2 0.38 6.5 0.33 2.85e-10 Schizophrenia; LIHC cis rs208520 0.837 rs208489 chr6:66927584 G/A cg07460842 chr6:66804631 NA -0.78 -8.51 -0.42 5.6e-16 Exhaled nitric oxide output; LIHC cis rs10791097 0.694 rs4937583 chr11:130741606 A/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1267303 0.675 rs1267308 chr1:46987718 A/G cg25110126 chr1:46999211 NA -0.49 -6.33 -0.32 7.51e-10 Monobrow; LIHC cis rs2842992 0.715 rs2277073 chr6:160182749 G/A cg11366901 chr6:160182831 ACAT2 0.93 15.83 0.65 9.84e-43 Age-related macular degeneration (geographic atrophy); LIHC cis rs9914988 0.943 rs1035989 chr17:27143810 T/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs4423214 0.879 rs1792281 chr11:71135496 G/A cg05163923 chr11:71159392 DHCR7 -0.63 -8.64 -0.42 2.17e-16 Vitamin D levels; LIHC cis rs2574704 1.000 rs7433453 chr3:11647416 C/T cg15876825 chr3:11651881 VGLL4 0.49 8.29 0.41 2.58e-15 Body mass index; LIHC cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg07061783 chr6:25882402 NA -0.52 -6.64 -0.34 1.2e-10 Intelligence (multi-trait analysis); LIHC cis rs422249 0.512 rs174546 chr11:61569830 C/T cg27386326 chr11:61587980 NA 0.7 14.82 0.63 9.56e-39 Trans fatty acid levels; LIHC cis rs9814567 1.000 rs7648990 chr3:134244390 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6952808 0.575 rs6950330 chr7:1953606 T/C cg03354898 chr7:1950403 MAD1L1 -0.38 -6.07 -0.31 3.49e-9 Bipolar disorder and schizophrenia; LIHC cis rs9341808 0.683 rs7771449 chr6:80919977 C/T cg08355045 chr6:80787529 NA 0.36 7.52 0.38 4.82e-13 Sitting height ratio; LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg03264133 chr6:25882463 NA -0.55 -7.05 -0.36 9.65e-12 Intelligence (multi-trait analysis); LIHC cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg16423285 chr20:60520624 NA 0.48 8.09 0.4 1.03e-14 Obesity-related traits; LIHC cis rs870825 0.616 rs28608669 chr4:185632890 T/C cg04058563 chr4:185651563 MLF1IP 0.77 7.68 0.38 1.67e-13 Blood protein levels; LIHC cis rs12824058 0.767 rs4759654 chr12:130815559 A/G cg24229701 chr12:130821962 PIWIL1 0.44 6.73 0.34 7.1e-11 Menopause (age at onset); LIHC cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg00934597 chr7:893267 UNC84A -0.64 -9.73 -0.47 6.32e-20 Perceived unattractiveness to mosquitoes; LIHC cis rs240764 0.817 rs239204 chr6:101135580 T/C cg09795085 chr6:101329169 ASCC3 0.52 7.13 0.36 6.1e-12 Neuroticism; LIHC cis rs6089584 0.888 rs6061973 chr20:60610870 C/T cg13770153 chr20:60521292 NA -0.34 -6.79 -0.34 4.83e-11 Body mass index; LIHC trans rs2727020 0.576 rs61885308 chr11:49343363 G/A cg15704280 chr7:45808275 SEPT13 -0.57 -8.89 -0.43 3.46e-17 Coronary artery disease; LIHC cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs116248771 0.739 rs12185969 chr3:158360880 C/T cg16708174 chr3:158430962 RARRES1 0.49 6.53 0.33 2.39e-10 diarrhoeal disease at age 2; LIHC cis rs12586317 0.547 rs115019197 chr14:35503764 G/A cg05294307 chr14:35346193 BAZ1A -0.5 -7.53 -0.38 4.65e-13 Psoriasis; LIHC cis rs2404602 0.692 rs34181263 chr15:77065388 C/T cg23625390 chr15:77176239 SCAPER 0.35 5.72 0.3 2.36e-8 Blood metabolite levels; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg11905131 chr22:24372483 LOC391322 -0.71 -10.58 -0.5 8.35e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2455799 0.613 rs7633542 chr3:15816326 C/T cg12698662 chr3:15914712 MIR563 -0.39 -7.33 -0.37 1.71e-12 Mean platelet volume; LIHC cis rs17253792 0.822 rs75991559 chr14:56092419 A/T cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs4638749 0.677 rs2100407 chr2:108830188 G/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.01 -0.31 4.69e-9 Blood pressure; LIHC cis rs7412746 0.658 rs8444 chr1:150938571 G/A cg15448220 chr1:150897856 SETDB1 0.44 6.86 0.35 3.24e-11 Melanoma; LIHC cis rs9733 0.596 rs72702570 chr1:150688196 C/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs11628318 0.614 rs10132160 chr14:103058023 A/G cg01864069 chr14:103024347 NA -0.48 -7.43 -0.37 8.65e-13 Platelet count; LIHC cis rs9948 0.881 rs3731941 chr2:97476219 A/G cg01990225 chr2:97406019 LMAN2L -0.67 -6.05 -0.31 3.77e-9 Erectile dysfunction and prostate cancer treatment; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg19497325 chr3:43121668 C3orf39 0.46 7.58 0.38 3.38e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg25072359 chr17:41440525 NA 0.37 5.9 0.3 8.75e-9 Menopause (age at onset); LIHC cis rs2153535 0.526 rs7748404 chr6:8472500 A/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs6964587 0.758 rs7798233 chr7:91500083 G/A cg17063962 chr7:91808500 NA -0.81 -8.29 -0.41 2.67e-15 Breast cancer; LIHC cis rs9768139 0.733 rs13221388 chr7:158119270 G/A cg06219351 chr7:158114137 PTPRN2 -0.21 -6.02 -0.31 4.53e-9 Calcium levels; LIHC cis rs908922 0.651 rs548252 chr1:152489742 A/G cg20991723 chr1:152506922 NA -0.57 -10.64 -0.5 5.14e-23 Hair morphology; LIHC cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg10360323 chr17:41437877 NA -0.41 -6.11 -0.31 2.72e-9 Menopause (age at onset); LIHC cis rs3096299 0.933 rs3114848 chr16:89452771 G/A cg06640241 chr16:89574553 SPG7 0.65 10.47 0.49 1.98e-22 Multiple myeloma (IgH translocation); LIHC trans rs11039798 0.925 rs7929225 chr11:48931739 G/C cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC trans rs2727020 0.615 rs35423199 chr11:49514914 T/C cg03929089 chr4:120376271 NA -0.89 -17.97 -0.7 2.71e-51 Coronary artery disease; LIHC cis rs12701220 0.739 rs2293523 chr7:1098518 G/A cg02733842 chr7:1102375 C7orf50 -0.68 -7.66 -0.38 1.92e-13 Bronchopulmonary dysplasia; LIHC cis rs6088590 1.000 rs6119530 chr20:33403930 A/G cg24642439 chr20:33292090 TP53INP2 0.77 10.54 0.5 1.1e-22 Coronary artery disease; LIHC cis rs9911578 0.900 rs717828 chr17:56535932 A/G cg12560992 chr17:57184187 TRIM37 0.95 16.99 0.68 2.32e-47 Intelligence (multi-trait analysis); LIHC cis rs1865760 1.000 rs3799372 chr6:25922311 A/G cg17691542 chr6:26056736 HIST1H1C 0.4 6.09 0.31 3.09e-9 Height; LIHC cis rs7086627 0.515 rs10887896 chr10:82210144 A/C cg01528321 chr10:82214614 TSPAN14 0.53 7.38 0.37 1.24e-12 Post bronchodilator FEV1; LIHC cis rs3008870 0.755 rs2815374 chr1:67507387 G/A cg02640540 chr1:67518911 SLC35D1 0.45 6.86 0.35 3.33e-11 Lymphocyte percentage of white cells; LIHC cis rs10744422 0.800 rs2649902 chr12:123243687 G/A cg25930673 chr12:123319894 HIP1R -0.81 -10.13 -0.48 2.8e-21 Schizophrenia; LIHC cis rs6088590 1.000 rs6088607 chr20:33378733 C/T cg24642439 chr20:33292090 TP53INP2 0.78 10.63 0.5 5.31e-23 Coronary artery disease; LIHC cis rs3820500 0.543 rs1289947 chr1:117954586 T/G cg20383390 chr1:117909022 MAN1A2 0.45 5.84 0.3 1.22e-8 Pneumonia; LIHC cis rs15676 0.947 rs10988124 chr9:131569345 G/A cg00228799 chr9:131580591 ENDOG 0.46 6.99 0.35 1.48e-11 Blood metabolite levels; LIHC cis rs7927771 0.832 rs10838704 chr11:47424717 T/C cg18512352 chr11:47633146 NA -0.26 -6.0 -0.31 4.9e-9 Subjective well-being; LIHC cis rs7264396 0.790 rs6058293 chr20:34248891 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.45 -0.53 6.66e-26 Total cholesterol levels; LIHC cis rs367615 0.879 rs56689485 chr5:108879828 A/T cg17395555 chr5:108820864 NA 0.35 7.13 0.36 6.1e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs7903847 0.642 rs9888117 chr10:99159963 C/G cg20016023 chr10:99160130 RRP12 -0.43 -6.79 -0.34 5.03e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg05590025 chr7:65112418 INTS4L2 -0.58 -6.43 -0.33 4.22e-10 Diabetic kidney disease; LIHC cis rs875971 0.862 rs10224872 chr7:65759773 T/A cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg24209194 chr3:40518798 ZNF619 0.56 8.1 0.4 9.7e-15 Renal cell carcinoma; LIHC cis rs765787 0.530 rs4774550 chr15:45542312 C/T cg24006582 chr15:45444508 DUOX1 -0.5 -7.17 -0.36 4.76e-12 Uric acid levels; LIHC cis rs2180341 0.961 rs3798857 chr6:127659473 A/T cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs4970988 0.556 rs6695123 chr1:150563483 T/C cg18016565 chr1:150552671 MCL1 -0.67 -13.25 -0.58 1.31e-32 Urate levels; LIHC cis rs9596863 1.000 rs7318666 chr13:54418960 C/G ch.13.53330881F chr13:54432880 NA -0.43 -6.0 -0.31 5.1e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs72634258 0.945 rs12730860 chr1:8132462 T/C cg00042356 chr1:8021962 PARK7 0.87 8.62 0.42 2.57e-16 Inflammatory bowel disease; LIHC cis rs7903847 0.596 rs9787426 chr10:99155327 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.41e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs921968 0.541 rs523305 chr2:219402691 T/C cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs6570726 0.846 rs426874 chr6:145880630 A/C cg05347473 chr6:146136440 FBXO30 0.36 6.0 0.31 5.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg19318889 chr4:1322082 MAEA 0.65 10.32 0.49 6.22e-22 Longevity; LIHC cis rs11690935 0.959 rs12692974 chr2:172663256 T/C cg13550731 chr2:172543902 DYNC1I2 -0.94 -17.83 -0.69 9.21e-51 Schizophrenia; LIHC trans rs7385804 0.761 rs507392 chr7:100319936 G/A cg02228481 chr6:31165922 HCG27 -0.46 -6.06 -0.31 3.64e-9 Iron status biomarkers;Mean corpuscular hemoglobin;Hematocrit;Iron status biomarkers (transferrin saturation);Red blood cell count;Iron status biomarkers (iron levels);Mean corpuscular volume;Hematological parameters; LIHC cis rs74233809 1.000 rs11191519 chr10:104784918 C/T cg03493300 chr10:104813866 CNNM2 0.46 6.24 0.32 1.31e-9 Birth weight; LIHC cis rs6684514 0.506 rs3762281 chr1:156304782 A/G cg20302342 chr1:156215951 PAQR6 0.3 6.05 0.31 3.79e-9 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs34779708 0.931 rs11010132 chr10:35517265 C/G cg04310649 chr10:35416472 CREM -0.42 -5.76 -0.3 1.85e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12893668 0.572 rs4900591 chr14:104154878 G/A cg24130564 chr14:104152367 KLC1 -0.55 -9.47 -0.46 4.67e-19 Reticulocyte count; LIHC cis rs240764 0.618 rs846778 chr6:101273147 T/C cg09795085 chr6:101329169 ASCC3 0.41 5.83 0.3 1.3e-8 Neuroticism; LIHC cis rs986417 0.901 rs1955687 chr14:60988606 A/G cg27398547 chr14:60952738 C14orf39 0.83 9.55 0.46 2.51e-19 Gut microbiota (bacterial taxa); LIHC cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg22907277 chr7:1156413 C7orf50 0.57 8.74 0.43 1.09e-16 Longevity;Endometriosis; LIHC cis rs12808519 0.688 rs3168175 chr11:69586070 A/C cg19831575 chr11:69590090 FGF4 0.5 6.9 0.35 2.55e-11 Urate levels in overweight individuals; LIHC cis rs8180040 0.966 rs60369822 chr3:47479735 A/C cg16586182 chr3:47516702 SCAP 0.61 11.81 0.54 3.13e-27 Colorectal cancer; LIHC cis rs12478296 0.681 rs56357900 chr2:243033966 A/C cg18898632 chr2:242989856 NA -0.57 -7.59 -0.38 3.11e-13 Obesity-related traits; LIHC cis rs2274273 0.840 rs28568813 chr14:55794114 C/G cg04306507 chr14:55594613 LGALS3 0.32 5.98 0.31 5.48e-9 Protein biomarker; LIHC cis rs918629 0.567 rs2546191 chr5:95232541 G/A cg10483112 chr5:95245456 ELL2 -0.36 -6.67 -0.34 1.04e-10 IgG glycosylation; LIHC cis rs4665809 0.759 rs62128394 chr2:26364026 T/G cg26119090 chr2:26468346 HADHA;HADHB 0.85 9.29 0.45 1.86e-18 Gut microbiome composition (summer); LIHC trans rs1005277 0.579 rs1740735 chr10:38497777 A/C cg27523141 chr10:43048294 ZNF37B 0.39 6.53 0.33 2.34e-10 Extrinsic epigenetic age acceleration; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25925670 chr17:2206573 SMG6;SRR -0.42 -6.08 -0.31 3.15e-9 Immature fraction of reticulocytes; LIHC cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.69 9.52 0.46 3.23e-19 Alzheimer's disease; LIHC trans rs11098499 0.954 rs4309825 chr4:120314881 C/T cg25214090 chr10:38739885 LOC399744 -0.53 -8.33 -0.41 1.93e-15 Corneal astigmatism; LIHC cis rs6430585 0.583 rs12475516 chr2:136560761 C/G cg07305463 chr2:136567211 LCT -0.37 -5.97 -0.31 6.07e-9 Corneal structure; LIHC cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg03517284 chr6:25882590 NA 0.48 6.07 0.31 3.35e-9 Intelligence (multi-trait analysis); LIHC cis rs875971 0.545 rs10950029 chr7:65634321 A/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.34 0.37 1.59e-12 Aortic root size; LIHC cis rs722599 0.651 rs7159354 chr14:75253847 A/G cg11812906 chr14:75593930 NEK9 0.41 6.13 0.31 2.47e-9 IgG glycosylation; LIHC cis rs6088580 0.634 rs6087588 chr20:33066369 T/C cg08999081 chr20:33150536 PIGU 0.67 13.39 0.59 3.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs2836974 0.526 rs1888488 chr21:40686521 C/T cg06238570 chr21:40685208 BRWD1 -0.54 -9.12 -0.44 6.72e-18 Cognitive function; LIHC cis rs7107174 1.000 rs4945267 chr11:78037933 G/A cg02023728 chr11:77925099 USP35 0.5 9.49 0.46 4.03e-19 Testicular germ cell tumor; LIHC cis rs10751667 0.666 rs7394427 chr11:970405 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs950776 0.648 rs57945453 chr15:78862845 C/T cg06917634 chr15:78832804 PSMA4 0.7 9.42 0.45 6.75e-19 Sudden cardiac arrest; LIHC cis rs780096 0.967 rs1260334 chr2:27748597 C/A cg22903471 chr2:27725779 GCKR -0.31 -5.81 -0.3 1.42e-8 Total body bone mineral density; LIHC cis rs10504229 1.000 rs59708460 chr8:58196526 G/A cg20607798 chr8:58055168 NA 0.57 6.65 0.34 1.13e-10 Developmental language disorder (linguistic errors); LIHC cis rs12220238 1.000 rs4745740 chr10:75942469 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.68 6.84 0.35 3.63e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs3741404 0.574 rs638227 chr11:63871549 T/C cg18225595 chr11:63971243 STIP1 0.46 7.35 0.37 1.44e-12 Platelet count; LIHC cis rs59698941 0.943 rs57880964 chr5:132210674 G/C cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs896854 0.902 rs726816 chr8:95968413 T/G cg23172400 chr8:95962367 TP53INP1 -0.37 -8.34 -0.41 1.84e-15 Type 2 diabetes; LIHC cis rs807669 0.565 rs5746682 chr22:19185526 C/T cg02655711 chr22:19163373 SLC25A1 0.47 7.81 0.39 7.12e-14 Metabolite levels; LIHC cis rs7095944 0.614 rs3824765 chr10:126433570 C/G cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.87e-10 Asthma; LIHC cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg02503808 chr4:7069936 GRPEL1 0.8 11.89 0.54 1.58e-27 Monocyte percentage of white cells; LIHC cis rs2404602 1.000 rs12594212 chr15:76802014 T/A cg23625390 chr15:77176239 SCAPER 0.41 6.84 0.35 3.73e-11 Blood metabolite levels; LIHC cis rs7208859 0.623 rs3794796 chr17:29130880 G/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg08392591 chr16:89556376 ANKRD11 0.55 8.81 0.43 6.45e-17 Multiple myeloma (IgH translocation); LIHC cis rs35883536 0.967 rs3904673 chr1:101137162 A/C cg14515779 chr1:101123966 NA -0.7 -14.03 -0.6 1.21e-35 Monocyte count; LIHC cis rs4243830 0.649 rs11579888 chr1:6609896 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.85 -10.84 -0.51 1.02e-23 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16377939 chr16:53088918 CHD9 -0.43 -6.27 -0.32 1.09e-9 Cognitive function; LIHC cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg16434002 chr17:42200994 HDAC5 0.51 7.36 0.37 1.41e-12 Total body bone mineral density; LIHC cis rs10089 0.953 rs6879970 chr5:127387178 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.73 0.34 7.16e-11 Ileal carcinoids; LIHC cis rs909002 0.772 rs12740754 chr1:32083273 G/C cg13919466 chr1:32135498 COL16A1 -0.32 -6.05 -0.31 3.85e-9 Intelligence (multi-trait analysis); LIHC cis rs4699052 1.000 rs7694190 chr4:104168017 A/G cg16532752 chr4:104119610 CENPE -0.39 -6.07 -0.31 3.44e-9 Testicular germ cell tumor; LIHC cis rs4969178 0.965 rs11077364 chr17:76400337 C/A cg20026190 chr17:76395443 PGS1 0.45 7.12 0.36 6.51e-12 HDL cholesterol levels; LIHC cis rs727505 1.000 rs113394869 chr7:124518172 G/C cg23710748 chr7:124431027 NA -0.33 -5.89 -0.3 9.1e-9 Lewy body disease; LIHC cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.83 -10.77 -0.5 1.78e-23 Alzheimer's disease; LIHC cis rs6499255 0.951 rs3743673 chr16:69711311 A/T cg15192750 chr16:69999425 NA 0.45 6.84 0.35 3.7e-11 IgE levels; LIHC cis rs1003719 0.788 rs2835602 chr21:38469069 G/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 11.95 0.54 9.44e-28 Eye color traits; LIHC cis rs763121 0.853 rs6001173 chr22:39015302 A/G cg14440974 chr22:39074834 NA -0.36 -5.98 -0.31 5.68e-9 Menopause (age at onset); LIHC cis rs116095464 0.558 rs2288458 chr5:231260 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.61 -0.5 6.24e-23 Breast cancer; LIHC cis rs11122272 0.766 rs2486732 chr1:231531476 A/C cg06096015 chr1:231504339 EGLN1 0.5 9.23 0.45 2.87e-18 Hemoglobin concentration; LIHC cis rs12586317 0.534 rs1568200 chr14:35419592 C/T cg05294307 chr14:35346193 BAZ1A -0.52 -8.14 -0.4 7.35e-15 Psoriasis; LIHC cis rs1707322 1.000 rs34694458 chr1:46332696 G/A cg03146154 chr1:46216737 IPP 0.47 7.47 0.37 6.55e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs35110281 0.659 rs11702544 chr21:45091861 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.15 0.32 2.22e-9 Mean corpuscular volume; LIHC cis rs12464559 0.649 rs4450595 chr2:152622603 T/C cg01189475 chr2:152685088 ARL5A 0.64 7.56 0.38 3.86e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg07424592 chr7:64974309 NA -0.8 -9.31 -0.45 1.58e-18 Diabetic kidney disease; LIHC cis rs7312933 0.558 rs1669936 chr12:42813509 C/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.23 -0.41 4.02e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7945705 0.870 rs4929922 chr11:8975776 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.41 -6.81 -0.35 4.27e-11 Hemoglobin concentration; LIHC cis rs963731 0.649 rs6756184 chr2:39256877 G/A cg04010122 chr2:39346883 SOS1 -0.65 -5.91 -0.3 8.21e-9 Corticobasal degeneration; LIHC cis rs16854884 0.657 rs62269895 chr3:143749085 C/G cg06585982 chr3:143692056 C3orf58 0.56 7.27 0.37 2.41e-12 Economic and political preferences (feminism/equality); LIHC cis rs1348850 0.632 rs13009207 chr2:178501632 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 8.19 0.41 5.16e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1707322 0.717 rs2991988 chr1:46082431 C/A cg06784218 chr1:46089804 CCDC17 -0.41 -7.45 -0.37 7.94e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1023500 0.753 rs12158335 chr22:42324622 T/G cg04733989 chr22:42467013 NAGA -0.5 -5.98 -0.31 5.51e-9 Schizophrenia; LIHC cis rs7552404 1.000 rs9662166 chr1:76235906 C/A cg22875332 chr1:76189707 ACADM 0.45 6.39 0.33 5.32e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs896854 0.812 rs4582532 chr8:95969257 G/A cg16049864 chr8:95962084 TP53INP1 -0.6 -11.48 -0.53 5.07e-26 Type 2 diabetes; LIHC cis rs9457247 0.756 rs2345572 chr6:167403441 A/T cg07741184 chr6:167504864 NA 0.32 7.39 0.37 1.14e-12 Crohn's disease; LIHC cis rs58688157 0.921 rs12805435 chr11:612355 T/C cg01842473 chr11:617407 IRF7;MUPCDH -0.57 -6.31 -0.32 8.65e-10 Systemic lupus erythematosus; LIHC cis rs2742417 0.603 rs2253979 chr3:45773320 A/G cg04837898 chr3:45731254 SACM1L -0.52 -8.69 -0.43 1.53e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs7914558 0.966 rs12766205 chr10:104893568 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg10360323 chr17:41437877 NA 0.4 5.9 0.3 8.65e-9 Menopause (age at onset); LIHC cis rs10463316 0.894 rs13361316 chr5:150765593 T/C cg03212797 chr5:150827313 SLC36A1 -0.44 -6.6 -0.34 1.54e-10 Metabolite levels (Pyroglutamine); LIHC cis rs13108904 0.517 rs13128825 chr4:1334007 G/A cg13395646 chr4:1353034 KIAA1530 -0.81 -12.43 -0.56 1.52e-29 Obesity-related traits; LIHC trans rs1005277 0.579 rs1740745 chr10:38520056 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs4845459 0.967 rs6700158 chr1:152592828 T/G cg18116418 chr1:152553244 LCE3D -0.31 -5.77 -0.3 1.74e-8 Psoriasis; LIHC cis rs72781680 1.000 rs17763442 chr2:24255991 C/T cg08917208 chr2:24149416 ATAD2B 0.81 6.13 0.31 2.38e-9 Lymphocyte counts; LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg10755058 chr3:40428713 ENTPD3 0.42 7.14 0.36 5.82e-12 Renal cell carcinoma; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg17158414 chr2:27665306 KRTCAP3 -0.42 -5.77 -0.3 1.81e-8 Total body bone mineral density; LIHC cis rs7107174 1.000 rs10899486 chr11:78072398 A/G cg02023728 chr11:77925099 USP35 0.46 8.79 0.43 7.22e-17 Testicular germ cell tumor; LIHC cis rs13343954 0.518 rs8106293 chr19:33536376 C/T cg03563238 chr19:33554763 RHPN2 -0.31 -5.9 -0.3 8.55e-9 Colorectal cancer; LIHC cis rs1580019 0.961 rs3801328 chr7:32496930 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs2070488 0.695 rs6599201 chr3:38476614 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.39 0.56 2.22e-29 Electrocardiographic conduction measures; LIHC cis rs7607369 0.714 rs4674334 chr2:219622811 T/C cg02176678 chr2:219576539 TTLL4 -0.44 -5.74 -0.3 2.06e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs7582180 0.764 rs12622318 chr2:100927375 T/C cg14675211 chr2:100938903 LONRF2 0.53 8.28 0.41 2.83e-15 Intelligence (multi-trait analysis); LIHC cis rs11958404 0.932 rs56065211 chr5:157439386 C/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs921968 0.643 rs586374 chr2:219383003 A/C cg18887096 chr2:219472410 PLCD4 0.36 6.46 0.33 3.52e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7923837 0.651 rs10882085 chr10:94364882 C/T cg25506282 chr10:94462361 NA 0.34 5.84 0.3 1.21e-8 Body mass index;Multiple sclerosis; LIHC cis rs796364 0.806 rs79897806 chr2:201073968 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.68 -7.19 -0.36 4.02e-12 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15854668 chr3:124449432 UMPS 0.42 6.12 0.31 2.6e-9 Cognitive function; LIHC cis rs4803455 0.565 rs11083616 chr19:41865643 A/G cg09537434 chr19:41945824 ATP5SL 0.7 10.63 0.5 5.61e-23 Migraine;Coronary artery disease; LIHC cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg22907277 chr7:1156413 C7orf50 0.73 5.99 0.31 5.32e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2070488 0.931 rs6599212 chr3:38558906 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.6 -0.62 7.5e-38 Electrocardiographic conduction measures; LIHC cis rs6788895 1.000 rs73008905 chr3:150465435 T/C cg07663535 chr3:150480033 SIAH2 0.56 7.0 0.35 1.37e-11 Breast cancer; LIHC cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg08888203 chr3:10149979 C3orf24 0.59 6.93 0.35 2.13e-11 Alzheimer's disease; LIHC cis rs8114671 0.869 rs66535333 chr20:33656666 G/A cg07148914 chr20:33460835 GGT7 -0.55 -8.3 -0.41 2.48e-15 Height; LIHC cis rs875971 0.825 rs10281499 chr7:66048966 A/G cg18252515 chr7:66147081 NA 0.45 6.57 0.33 1.83e-10 Aortic root size; LIHC cis rs2243480 0.901 rs778730 chr7:65823325 T/A cg05590025 chr7:65112418 INTS4L2 -0.56 -6.14 -0.32 2.23e-9 Diabetic kidney disease; LIHC cis rs17401966 0.894 rs12722830 chr1:10395134 A/G cg19773385 chr1:10388646 KIF1B -0.39 -6.88 -0.35 2.85e-11 Hepatocellular carcinoma; LIHC cis rs7408868 0.908 rs45591935 chr19:15277006 T/C cg14696996 chr19:15285081 NOTCH3 0.54 7.17 0.36 4.71e-12 Pulse pressure; LIHC cis rs7534824 0.625 rs12561853 chr1:101457863 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.73 -7.99 -0.4 2.12e-14 Refractive astigmatism; LIHC cis rs250677 0.652 rs36042 chr5:148439782 G/T cg12140854 chr5:148520817 ABLIM3 -0.53 -5.9 -0.3 8.73e-9 Breast cancer; LIHC cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg18230493 chr5:56204884 C5orf35 -0.46 -6.46 -0.33 3.51e-10 Initial pursuit acceleration; LIHC cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg18230493 chr5:56204884 C5orf35 -0.43 -6.03 -0.31 4.26e-9 Initial pursuit acceleration; LIHC cis rs4629710 0.545 rs11154621 chr6:131547341 A/G cg12606694 chr6:131520996 AKAP7 0.66 7.96 0.4 2.59e-14 Multiple myeloma (IgH translocation); LIHC cis rs9303401 1.000 rs9904677 chr17:56873025 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.43 6.43 0.33 4.19e-10 Cognitive test performance; LIHC cis rs1577917 0.771 rs2842607 chr6:86345039 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -12.25 -0.55 7.35e-29 Response to antipsychotic treatment; LIHC cis rs753955 0.593 rs7982516 chr13:24410278 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.38 6.87 0.35 3.14e-11 Lung cancer; LIHC cis rs459571 0.959 rs456205 chr9:136911146 G/A cg13789015 chr9:136890014 NCRNA00094 0.46 8.47 0.42 7.26e-16 Platelet distribution width; LIHC cis rs6570726 0.846 rs439035 chr6:145887990 G/C cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.2e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4927850 1.000 rs4927704 chr3:195738228 C/T cg01181863 chr3:195395398 SDHAP2 -0.63 -8.0 -0.4 1.98e-14 Pancreatic cancer; LIHC cis rs929354 0.772 rs2366214 chr7:156992461 A/G cg16102536 chr7:156981717 UBE3C 0.36 5.96 0.31 6.19e-9 Body mass index; LIHC cis rs6570726 1.000 rs373778 chr6:145873252 C/T cg23711669 chr6:146136114 FBXO30 0.53 9.26 0.45 2.4e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs4727027 0.754 rs917124 chr7:148851213 C/T cg23583168 chr7:148888333 NA -0.71 -9.23 -0.45 3e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs13217239 0.646 rs10456352 chr6:26990358 A/T cg18867708 chr6:26865862 GUSBL1 0.53 8.11 0.4 8.86e-15 Schizophrenia; LIHC cis rs7412746 0.611 rs10888391 chr1:150729983 G/A cg17724175 chr1:150552817 MCL1 0.47 9.44 0.45 6.14e-19 Melanoma; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09924173 chr13:32526671 EEF1DP3 0.49 6.38 0.33 5.78e-10 Hepatitis; LIHC cis rs35883536 0.647 rs10875313 chr1:101043057 T/C cg14515779 chr1:101123966 NA 0.46 6.5 0.33 2.8e-10 Monocyte count; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg10755058 chr3:40428713 ENTPD3 0.4 6.78 0.34 5.27e-11 Renal cell carcinoma; LIHC cis rs28453840 1 rs28453840 chr2:136522941 G/A cg15123519 chr2:136567270 LCT 0.44 8.81 0.43 6.22e-17 Cholesterol, total; LIHC trans rs2797160 0.714 rs1777220 chr6:126022602 G/T cg05039488 chr6:79577232 IRAK1BP1 0.54 7.34 0.37 1.55e-12 Endometrial cancer; LIHC cis rs7107174 1.000 rs12277648 chr11:78054336 C/T cg02023728 chr11:77925099 USP35 0.43 8.32 0.41 2.1e-15 Testicular germ cell tumor; LIHC cis rs4474465 1.000 rs10899513 chr11:78172353 T/C cg02023728 chr11:77925099 USP35 0.32 5.82 0.3 1.34e-8 Alzheimer's disease (survival time); LIHC cis rs36051895 0.664 rs7852755 chr9:5100862 C/T cg02405213 chr9:5042618 JAK2 -0.69 -11.77 -0.54 4.38e-27 Pediatric autoimmune diseases; LIHC cis rs11673344 0.704 rs485034 chr19:37422357 T/G cg27390819 chr19:37464633 NA -0.51 -6.07 -0.31 3.38e-9 Obesity-related traits; LIHC cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg13047869 chr3:10149882 C3orf24 0.53 6.86 0.35 3.24e-11 Alzheimer's disease; LIHC cis rs9402673 0.517 rs978036 chr6:135342903 C/T cg24558204 chr6:135376177 HBS1L 0.42 6.86 0.35 3.16e-11 Reticulocyte count;High light scatter reticulocyte count; LIHC cis rs9534288 0.762 rs4941539 chr13:46597067 A/T cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs4727027 0.901 rs12671341 chr7:148805282 T/C cg23583168 chr7:148888333 NA -0.68 -9.58 -0.46 2.05e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs5760092 0.755 rs4585126 chr22:24270005 T/C cg06437703 chr8:37914619 EIF4EBP1 0.63 8.91 0.43 3.17e-17 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs11098499 0.644 rs7676296 chr4:120555687 A/G cg09307838 chr4:120376055 NA 0.67 10.26 0.49 9.99e-22 Corneal astigmatism; LIHC cis rs7617773 0.851 rs7647817 chr3:48236507 G/A cg11946769 chr3:48343235 NME6 0.9 11.19 0.52 5.8e-25 Coronary artery disease; LIHC trans rs8001976 0.510 rs9645941 chr13:48331361 G/C cg22135685 chr5:107205065 FBXL17 -0.33 -6.05 -0.31 3.76e-9 Aging (time to event); LIHC cis rs17106184 1.000 rs3827731 chr1:50987827 A/G cg07174182 chr1:51127561 FAF1 -0.7 -7.11 -0.36 6.97e-12 Type 2 diabetes; LIHC cis rs6754311 0.551 rs9287442 chr2:136522710 A/G cg07169764 chr2:136633963 MCM6 -0.74 -10.64 -0.5 5.17e-23 Mosquito bite size; LIHC cis rs11628318 0.802 rs2277471 chr14:103024387 A/C cg23461800 chr14:103021989 NA 0.52 7.53 0.38 4.62e-13 Platelet count; LIHC cis rs4474465 0.915 rs12274873 chr11:78183015 C/G cg27205649 chr11:78285834 NARS2 -0.38 -5.95 -0.31 6.79e-9 Alzheimer's disease (survival time); LIHC cis rs7903847 0.642 rs11189177 chr10:99141663 C/T cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs1005277 0.602 rs2504142 chr10:38383793 C/T cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs8177253 1.000 rs8177262 chr3:133480652 A/G cg12373951 chr3:133503437 NA -0.69 -12.4 -0.56 2.07e-29 Iron status biomarkers; LIHC cis rs763121 0.925 rs17032 chr22:39130843 C/G cg06544989 chr22:39130855 UNC84B 0.35 5.85 0.3 1.17e-8 Menopause (age at onset); LIHC cis rs344364 0.511 rs1657133 chr16:1950300 A/G cg26897989 chr16:1907736 C16orf73 -0.5 -6.18 -0.32 1.84e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs9399135 0.684 rs1135205 chr6:135281795 C/T cg24558204 chr6:135376177 HBS1L 0.39 6.45 0.33 3.92e-10 Red blood cell count; LIHC trans rs875971 0.545 rs2173571 chr7:65770379 G/A cg26939375 chr7:64535504 NA 0.4 6.34 0.32 7.06e-10 Aortic root size; LIHC cis rs600806 0.778 rs10776698 chr1:110013630 C/T cg02415029 chr1:110025642 ATXN7L2 -0.49 -6.32 -0.32 8.24e-10 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03550219 chr3:25705846 TOP2B -0.46 -6.44 -0.33 4e-10 Pancreatic cancer; LIHC cis rs7959452 0.535 rs4761228 chr12:69682327 G/A cg20891283 chr12:69753455 YEATS4 0.81 15.05 0.63 1.23e-39 Blood protein levels; LIHC cis rs12908161 0.959 rs12908699 chr15:85240403 G/T cg03959625 chr15:84868606 LOC388152 0.42 5.95 0.31 6.79e-9 Schizophrenia; LIHC cis rs7106204 0.668 rs7119198 chr11:24218267 A/G ch.11.24196551F chr11:24239977 NA 0.78 10.57 0.5 8.81e-23 Response to Homoharringtonine (cytotoxicity); LIHC cis rs875971 0.638 rs6460305 chr7:66060408 G/A cg14393609 chr7:65229607 NA -0.38 -5.98 -0.31 5.66e-9 Aortic root size; LIHC cis rs16958440 1.000 rs62096466 chr18:44636171 T/G cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC cis rs875971 1.000 rs709597 chr7:65825983 A/G cg18876405 chr7:65276391 NA -0.35 -6.48 -0.33 3.27e-10 Aortic root size; LIHC trans rs12310956 0.532 rs1589902 chr12:33989289 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.7 0.34 8.68e-11 Morning vs. evening chronotype; LIHC cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg02187348 chr16:89574699 SPG7 0.66 10.47 0.49 1.96e-22 Multiple myeloma (IgH translocation); LIHC cis rs742115 0.563 rs2281063 chr6:11298263 T/C cg25250968 chr6:11318770 NEDD9 -0.4 -6.21 -0.32 1.49e-9 Coronary artery disease; LIHC trans rs12692119 0.655 rs12469732 chr2:127653376 T/C cg13995918 chr5:1280305 TERT -0.46 -6.42 -0.33 4.63e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs6456156 0.565 rs12525345 chr6:167478875 T/C cg23791538 chr6:167370224 RNASET2 -0.53 -8.58 -0.42 3.34e-16 Primary biliary cholangitis; LIHC cis rs365132 1.000 rs353464 chr5:176403023 A/G cg16309518 chr5:176445507 NA -0.58 -11.4 -0.52 1.01e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs763121 0.853 rs9622833 chr22:39000397 G/A cg14440974 chr22:39074834 NA -0.44 -6.98 -0.35 1.58e-11 Menopause (age at onset); LIHC cis rs2073300 0.609 rs6137930 chr20:23376732 G/A cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs826838 0.935 rs11169508 chr12:39173385 C/T cg26384229 chr12:38710491 ALG10B 0.85 11.03 0.51 2.17e-24 Heart rate; LIHC cis rs9467773 0.933 rs35355150 chr6:26526039 G/A cg09904177 chr6:26538194 HMGN4 0.62 12.45 0.56 1.37e-29 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs7829975 0.681 rs2271342 chr8:8643938 C/T cg06636001 chr8:8085503 FLJ10661 0.49 7.72 0.39 1.31e-13 Mood instability; LIHC trans rs13113518 0.812 rs4507426 chr4:56395554 T/C cg15358633 chr12:38710606 ALG10B 0.43 6.16 0.32 2.09e-9 Height; LIHC cis rs7937682 0.883 rs568506 chr11:111466429 C/T cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg13770153 chr20:60521292 NA -0.36 -7.22 -0.36 3.43e-12 Body mass index; LIHC cis rs6732160 0.691 rs13402225 chr2:73416906 T/G cg24220031 chr2:73402428 NA -0.28 -6.06 -0.31 3.59e-9 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.931 rs34304999 chr10:35365705 C/T cg03585969 chr10:35415529 CREM 0.85 12.93 0.57 2.16e-31 Inflammatory bowel disease;Crohn's disease; LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg26119740 chr11:73881915 C2CD3;PPME1 -0.45 -6.12 -0.31 2.59e-9 Thyroid stimulating hormone; LIHC cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg05564831 chr3:52568323 NT5DC2 0.37 6.03 0.31 4.19e-9 Bipolar disorder; LIHC cis rs7560272 0.723 rs1083923 chr2:73703374 A/G cg20560298 chr2:73613845 ALMS1 0.36 5.83 0.3 1.26e-8 Schizophrenia; LIHC cis rs9952991 0.941 rs2847278 chr18:12778715 C/T cg23598886 chr18:12777645 NA 0.48 6.51 0.33 2.69e-10 Inflammatory skin disease; LIHC cis rs11888559 0.655 rs6435173 chr2:204013112 A/G cg24605529 chr2:203879461 NBEAL1 0.78 5.92 0.31 7.62e-9 Height; LIHC cis rs9457247 0.765 rs9459849 chr6:167444160 G/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.11 -0.4 8.87e-15 Crohn's disease; LIHC cis rs4721295 0.546 rs1637766 chr7:2204400 G/A cg22963979 chr7:1858916 MAD1L1 0.38 5.88 0.3 9.79e-9 Schizophrenia, schizoaffective disorder or bipolar disorder; LIHC cis rs74233809 1.000 rs112390216 chr10:104741031 C/T cg03493300 chr10:104813866 CNNM2 0.44 5.76 0.3 1.87e-8 Birth weight; LIHC cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg27572855 chr1:25598939 RHD -0.39 -8.4 -0.41 1.17e-15 Erythrocyte sedimentation rate; LIHC cis rs11031096 0.678 rs4606468 chr11:4183643 G/T cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.42e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs428668 0.523 rs10060607 chr5:150679304 A/C cg11125805 chr5:150678162 SLC36A3 0.53 11.9 0.54 1.46e-27 Skin aging (microtopography measurement); LIHC cis rs35110281 0.744 rs230646 chr21:44918788 A/G cg21573476 chr21:45109991 RRP1B -0.53 -9.42 -0.45 7.01e-19 Mean corpuscular volume; LIHC cis rs67460515 0.892 rs6780536 chr3:161058726 T/C cg17135325 chr3:160939158 NMD3 0.55 8.03 0.4 1.58e-14 Parkinson's disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg04686763 chr11:64655583 NA 0.41 6.68 0.34 9.92e-11 Calcium levels; LIHC cis rs7552404 0.691 rs5745449 chr1:76344711 A/T cg03433033 chr1:76189801 ACADM -0.55 -6.51 -0.33 2.67e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg03806693 chr22:41940476 POLR3H -0.97 -11.35 -0.52 1.51e-25 Vitiligo; LIHC cis rs2836950 0.565 rs2150414 chr21:40614988 A/G cg11890956 chr21:40555474 PSMG1 -0.46 -7.54 -0.38 4.34e-13 Menarche (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13398864 chr3:122920640 SEC22A 0.49 6.55 0.33 2.11e-10 Lung function (FEV1/FVC); LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg13409248 chr3:40428643 ENTPD3 0.5 8.41 0.41 1.11e-15 Renal cell carcinoma; LIHC trans rs116095464 0.558 rs62344345 chr5:257420 C/T cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs769267 0.930 rs10422819 chr19:19643028 C/A cg03709012 chr19:19516395 GATAD2A 1.01 16.54 0.67 1.49e-45 Tonsillectomy; LIHC cis rs2236918 0.901 rs1776135 chr1:242025530 A/G cg17736920 chr1:242011382 EXO1 0.6 8.96 0.44 2.15e-17 Menopause (age at onset); LIHC cis rs4423214 0.879 rs1790324 chr11:71150520 A/C cg05163923 chr11:71159392 DHCR7 -0.62 -8.58 -0.42 3.3e-16 Vitamin D levels; LIHC trans rs11098499 0.909 rs11723757 chr4:120299669 C/T cg25214090 chr10:38739885 LOC399744 0.55 8.66 0.42 1.95e-16 Corneal astigmatism; LIHC cis rs7615952 0.576 rs4646759 chr3:125822946 G/C cg05084668 chr3:125655381 ALG1L -0.4 -6.04 -0.31 4.12e-9 Blood pressure (smoking interaction); LIHC cis rs988712 0.705 rs4074134 chr11:27647285 C/T cg18117895 chr11:27722066 BDNF 0.45 6.11 0.31 2.68e-9 Obesity; LIHC cis rs10493773 0.566 rs11161659 chr1:86183967 T/C cg17807903 chr1:86174739 ZNHIT6 -0.6 -11.59 -0.53 2e-26 Urate levels in overweight individuals; LIHC cis rs9303401 0.614 rs34058624 chr17:57118121 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.89 12.34 0.55 3.59e-29 Cognitive test performance; LIHC cis rs9611519 0.828 rs28814423 chr22:41452301 G/A cg03806693 chr22:41940476 POLR3H -0.71 -7.72 -0.39 1.29e-13 Neuroticism; LIHC cis rs8062405 0.698 rs10499 chr16:28915527 G/A cg07451762 chr16:28383216 NA -0.36 -6.38 -0.33 5.76e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6754311 0.773 rs309176 chr2:136622216 T/C cg07305463 chr2:136567211 LCT 0.38 7.49 0.38 5.86e-13 Mosquito bite size; LIHC cis rs763121 0.853 rs138713 chr22:39142615 T/C cg06022373 chr22:39101656 GTPBP1 0.69 12.71 0.57 1.4e-30 Menopause (age at onset); LIHC cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg23649088 chr2:200775458 C2orf69 0.58 8.3 0.41 2.4e-15 Osteoporosis; LIHC trans rs1005277 0.579 rs2505196 chr10:38393563 G/A cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs4742903 0.904 rs971969 chr9:106929798 A/C cg14250997 chr9:106856677 SMC2 0.36 6.03 0.31 4.36e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs929354 0.772 rs6957939 chr7:156978485 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs208520 0.742 rs208454 chr6:66907783 T/C cg07460842 chr6:66804631 NA -0.7 -7.58 -0.38 3.24e-13 Exhaled nitric oxide output; LIHC cis rs1789 0.839 rs9997068 chr4:15650990 T/C cg24225360 chr4:15471699 CC2D2A -0.39 -6.17 -0.32 1.9e-9 Blood protein levels; LIHC cis rs6062302 0.522 rs6089929 chr20:62219679 C/T cg06363034 chr20:62225388 GMEB2 -0.43 -7.36 -0.37 1.37e-12 Glioblastoma; LIHC trans rs1728785 0.901 rs12929568 chr16:68596689 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.48 0.33 3.16e-10 Ulcerative colitis; LIHC trans rs950169 0.579 rs62027818 chr15:84661145 T/C cg00571809 chr1:3397113 ARHGEF16 0.39 6.39 0.33 5.55e-10 Schizophrenia; LIHC cis rs4808199 0.901 rs12973258 chr19:19488718 T/C cg03709012 chr19:19516395 GATAD2A 1.08 19.14 0.72 5.04e-56 Nonalcoholic fatty liver disease; LIHC trans rs9600079 0.680 rs9530152 chr13:73715441 C/T cg18908524 chr11:64002295 VEGFB -0.55 -6.26 -0.32 1.15e-9 Prostate cancer; LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg12379764 chr21:47803548 PCNT -0.55 -7.93 -0.39 3.19e-14 Testicular germ cell tumor; LIHC cis rs2576037 0.583 rs2576050 chr18:44558912 T/C cg19077165 chr18:44547161 KATNAL2 0.47 7.1 0.36 7.12e-12 Personality dimensions; LIHC cis rs703842 0.616 rs7489290 chr12:58228588 C/G cg04478727 chr12:58166393 METTL1;FAM119B 0.65 9.17 0.44 4.5e-18 Multiple sclerosis; LIHC cis rs597539 0.652 rs660614 chr11:68659488 G/A cg04772025 chr11:68637568 NA 0.47 6.26 0.32 1.12e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1707322 1.000 rs1707317 chr1:46510642 C/T cg03146154 chr1:46216737 IPP -0.45 -7.25 -0.36 2.82e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12477438 0.798 rs2045057 chr2:99684929 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.85 -0.65 8.31e-43 Chronic sinus infection; LIHC cis rs9611565 0.559 rs132761 chr22:42004371 C/T cg06634786 chr22:41940651 POLR3H 0.71 7.38 0.37 1.23e-12 Vitiligo; LIHC cis rs9921222 0.692 rs11860497 chr16:405416 A/G cg12437481 chr16:420112 MRPL28 -0.54 -8.33 -0.41 2.03e-15 Bone mineral density (spine);Bone mineral density; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg23640757 chr6:7889014 TXNDC5 0.51 6.89 0.35 2.72e-11 Hip circumference; LIHC cis rs7615952 0.641 rs66520539 chr3:125780374 G/A cg05084668 chr3:125655381 ALG1L -0.41 -6.38 -0.33 5.63e-10 Blood pressure (smoking interaction); LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg11494091 chr17:61959527 GH2 0.35 5.86 0.3 1.11e-8 Height; LIHC cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg15857475 chr8:145742913 RECQL4;LRRC14 -0.54 -8.0 -0.4 1.91e-14 Age at first birth; LIHC cis rs3008870 1.000 rs12039172 chr1:67447450 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC trans rs3942852 0.774 rs10838813 chr11:48186969 C/A cg03929089 chr4:120376271 NA -0.56 -7.6 -0.38 2.9e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs6754311 0.773 rs309180 chr2:136614255 A/G cg15123519 chr2:136567270 LCT -0.42 -8.77 -0.43 8.74e-17 Mosquito bite size; LIHC cis rs7707921 0.881 rs73136782 chr5:81443520 T/G cg15871215 chr5:81402204 ATG10 -0.63 -6.25 -0.32 1.26e-9 Breast cancer; LIHC cis rs12478296 0.786 rs28802397 chr2:243049730 G/A cg18898632 chr2:242989856 NA -0.57 -7.74 -0.39 1.11e-13 Obesity-related traits; LIHC cis rs1434579 0.966 rs7246892 chr19:44928668 A/G cg15540054 chr19:45004280 ZNF180 0.55 7.52 0.38 4.89e-13 Tuberculosis; LIHC cis rs1816752 0.905 rs3818938 chr13:25029083 C/T cg22771759 chr13:24902376 NA 0.32 6.93 0.35 2.05e-11 Obesity-related traits; LIHC trans rs208520 1.000 rs208520 chr6:66952828 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.63 -6.68 -0.34 9.52e-11 Exhaled nitric oxide output; LIHC cis rs6076065 0.748 rs2281431 chr20:23399304 C/G cg11657817 chr20:23433608 CST11 0.31 6.57 0.33 1.91e-10 Facial morphology (factor 15, philtrum width); LIHC cis rs11864453 0.612 rs12924413 chr16:72129745 T/C cg01557791 chr16:72042693 DHODH -0.45 -7.52 -0.38 4.95e-13 Fibrinogen levels; LIHC cis rs67478160 0.643 rs8005594 chr14:104279889 T/C cg08213375 chr14:104286397 PPP1R13B 0.65 12.64 0.56 2.5e-30 Schizophrenia; LIHC cis rs2242420 0.920 rs10917028 chr1:21963854 C/T cg18150885 chr1:21978612 RAP1GAP -0.49 -5.86 -0.3 1.11e-8 Hematological and biochemical traits; LIHC cis rs1055129 0.560 rs9891076 chr17:73911715 C/T cg10935138 chr17:73851978 WBP2 0.49 7.27 0.37 2.52e-12 White matter hyperintensity burden; LIHC cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg10130564 chr11:117069849 TAGLN 0.35 5.93 0.31 7.49e-9 Blood protein levels; LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg04267008 chr7:1944627 MAD1L1 0.65 10.88 0.51 7.29e-24 Bipolar disorder and schizophrenia; LIHC cis rs11864453 0.647 rs3764311 chr16:72125617 C/G cg16558253 chr16:72132732 DHX38 -0.45 -7.26 -0.37 2.55e-12 Fibrinogen levels; LIHC cis rs6430585 0.591 rs12466487 chr2:136407078 C/T cg07169764 chr2:136633963 MCM6 -0.63 -7.73 -0.39 1.23e-13 Corneal structure; LIHC cis rs9916302 0.784 rs4795382 chr17:37700860 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.13 -0.58 3.45e-32 Glomerular filtration rate (creatinine); LIHC trans rs1814175 0.817 rs10839318 chr11:49657511 G/C cg18944383 chr4:111397179 ENPEP 0.24 6.14 0.32 2.31e-9 Height; LIHC cis rs992157 0.710 rs12612347 chr2:219057338 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.79 -13.15 -0.58 2.9e-32 Colorectal cancer; LIHC cis rs7799006 0.755 rs2256545 chr7:2291943 G/A cg02951883 chr7:2050386 MAD1L1 -0.4 -6.15 -0.32 2.16e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7707921 0.881 rs73134747 chr5:81378294 C/T cg15871215 chr5:81402204 ATG10 -0.59 -5.71 -0.3 2.44e-8 Breast cancer; LIHC cis rs875971 0.862 rs7782704 chr7:65805366 G/A cg18252515 chr7:66147081 NA 0.44 6.34 0.32 7.48e-10 Aortic root size; LIHC trans rs7246657 0.943 rs10417844 chr19:37837587 C/T cg24637308 chr11:6592297 DNHD1 0.43 6.09 0.31 2.99e-9 Coronary artery calcification; LIHC cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg11494091 chr17:61959527 GH2 0.36 5.81 0.3 1.4e-8 Height; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 11.82 0.54 2.92e-27 Prudent dietary pattern; LIHC cis rs4474465 0.679 rs10899537 chr11:78222424 C/G cg02023728 chr11:77925099 USP35 -0.33 -5.84 -0.3 1.2e-8 Alzheimer's disease (survival time); LIHC cis rs10197940 0.662 rs6735771 chr2:152273503 G/A cg06191203 chr2:152266755 RIF1 0.46 7.83 0.39 6.01e-14 Lung cancer; LIHC cis rs2522056 0.808 rs7704457 chr5:131744790 C/T cg24060327 chr5:131705240 SLC22A5 -0.63 -8.64 -0.42 2.18e-16 Lymphocyte counts;Fibrinogen; LIHC trans rs1945213 0.694 rs11227113 chr11:55828024 C/T cg15704280 chr7:45808275 SEPT13 0.6 7.61 0.38 2.75e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs7772486 0.790 rs9403755 chr6:146231470 C/A cg13319975 chr6:146136371 FBXO30 0.35 5.81 0.3 1.39e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7249142 0.573 rs2238668 chr19:19282597 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.93 -0.35 2.11e-11 IgG glycosylation; LIHC cis rs2637266 0.599 rs846574 chr10:78503082 G/A cg18941641 chr10:78392320 NA 0.28 6.07 0.31 3.34e-9 Pulmonary function; LIHC cis rs12711979 0.509 rs13005405 chr2:3826324 C/T cg17052675 chr2:3827356 NA -0.71 -15.75 -0.65 2.12e-42 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs807029 0.533 rs722435 chr10:102745062 G/T cg25179470 chr10:102756915 LZTS2 0.45 6.38 0.33 5.65e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9814567 1.000 rs9864346 chr3:134312352 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.0 -0.31 5.1e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9902453 0.904 rs12948898 chr17:28410324 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -13.25 -0.58 1.21e-32 Coffee consumption (cups per day); LIHC cis rs6088580 0.634 rs6088488 chr20:32992631 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs7552404 1.000 rs72686191 chr1:76218319 G/T cg03433033 chr1:76189801 ACADM 0.67 9.3 0.45 1.74e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg00280220 chr17:61926910 NA 0.41 6.46 0.33 3.6e-10 Prudent dietary pattern; LIHC cis rs2455799 0.613 rs4685264 chr3:15858347 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.5 -0.38 5.71e-13 Mean platelet volume; LIHC cis rs4332037 0.539 rs57148375 chr7:2025001 G/C cg23422044 chr7:1970798 MAD1L1 -0.62 -6.92 -0.35 2.23e-11 Bipolar disorder; LIHC cis rs1707322 0.964 rs12067716 chr1:46434428 T/A cg06784218 chr1:46089804 CCDC17 0.37 6.67 0.34 1.06e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6088590 0.610 rs6120663 chr20:33081906 A/C cg06115741 chr20:33292138 TP53INP2 -0.5 -6.93 -0.35 2.09e-11 Coronary artery disease; LIHC cis rs651907 0.557 rs35850993 chr3:101437433 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.67 0.53 1e-26 Colorectal cancer; LIHC cis rs769267 0.831 rs2872878 chr19:19480521 G/C cg03709012 chr19:19516395 GATAD2A -1.01 -17.44 -0.69 3.39e-49 Tonsillectomy; LIHC cis rs904251 0.504 rs1757188 chr6:37483808 A/G cg01843034 chr6:37503916 NA -0.47 -8.13 -0.4 7.92e-15 Cognitive performance; LIHC cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.47 6.48 0.33 3.27e-10 Bipolar disorder; LIHC cis rs34779708 0.658 rs4934715 chr10:35364992 G/T cg03585969 chr10:35415529 CREM 0.87 13.18 0.58 2.32e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs8114671 0.562 rs6088642 chr20:33483186 G/T cg07148914 chr20:33460835 GGT7 0.65 9.86 0.47 2.39e-20 Height; LIHC cis rs6586163 0.872 rs1800682 chr10:90749963 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.56 -8.27 -0.41 3.09e-15 Chronic lymphocytic leukemia; LIHC cis rs6545883 0.862 rs778141 chr2:61682178 A/G cg14146966 chr2:61757674 XPO1 0.48 8.31 0.41 2.23e-15 Tuberculosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21315798 chr22:50354594 PIM3 -0.42 -6.7 -0.34 8.62e-11 Cognitive function; LIHC cis rs9549328 0.878 rs9577407 chr13:113639671 G/A cg08890338 chr13:113700818 MCF2L -0.35 -5.9 -0.3 8.9e-9 Systolic blood pressure; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg05484376 chr2:27715224 FNDC4 0.36 6.09 0.31 3.04e-9 Total body bone mineral density; LIHC cis rs1008375 1.000 rs4642241 chr4:17617111 T/C cg16339924 chr4:17578868 LAP3 0.45 6.22 0.32 1.45e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs17125944 0.686 rs2296495 chr14:53379878 G/A cg00686598 chr14:53173677 PSMC6 0.88 9.48 0.46 4.34e-19 Alzheimer's disease (late onset); LIHC trans rs10506458 0.834 rs12426893 chr12:63388120 G/T cg22491629 chr6:157744540 C6orf35 -0.6 -10.81 -0.5 1.26e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs2576037 0.583 rs1970668 chr18:44523220 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.78 -0.3 1.65e-8 Personality dimensions; LIHC cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg11062466 chr8:58055876 NA 0.48 6.5 0.33 2.78e-10 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs28616694 chr21:46674786 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.43 0.53 7.82e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11229555 1.000 rs11229543 chr11:58370698 G/A cg15696309 chr11:58395628 NA -0.73 -8.95 -0.44 2.24e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05414835 chr15:59225898 SLTM 0.47 7.0 0.35 1.38e-11 Hepatitis; LIHC cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg25364880 chr3:44379878 C3orf23 0.61 8.39 0.41 1.29e-15 Depressive symptoms; LIHC cis rs919433 0.963 rs4850428 chr2:198169772 G/A cg10820045 chr2:198174542 NA -0.57 -9.53 -0.46 3.02e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11690935 0.959 rs11897196 chr2:172585595 G/A cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.71 -0.69 2.99e-50 Schizophrenia; LIHC cis rs2717559 0.542 rs11777634 chr8:143887957 C/T cg07661805 chr8:143867942 LY6D -0.31 -6.64 -0.34 1.21e-10 Urinary tract infection frequency; LIHC cis rs4843747 0.671 rs28465438 chr16:88103714 G/A cg07560587 chr16:88016574 BANP 0.35 5.81 0.3 1.4e-8 Menopause (age at onset); LIHC cis rs600806 0.778 rs11101961 chr1:110008813 T/C cg11161837 chr1:110010384 SYPL2 0.46 6.3 0.32 9.14e-10 Intelligence (multi-trait analysis); LIHC cis rs4713118 0.516 rs4713142 chr6:28106347 T/G cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Parkinson's disease; LIHC cis rs986417 1.000 rs1254298 chr14:60883842 C/T cg27398547 chr14:60952738 C14orf39 -0.74 -8.61 -0.42 2.67e-16 Gut microbiota (bacterial taxa); LIHC cis rs644148 0.836 rs2686775 chr19:45000059 C/T cg15540054 chr19:45004280 ZNF180 -0.77 -11.57 -0.53 2.29e-26 Personality dimensions; LIHC cis rs7666738 0.606 rs4699606 chr4:99095074 A/C cg05340658 chr4:99064831 C4orf37 -0.57 -9.55 -0.46 2.58e-19 Colonoscopy-negative controls vs population controls; LIHC cis rs9399135 0.935 rs6908681 chr6:135337733 A/G cg24558204 chr6:135376177 HBS1L 0.41 6.8 0.35 4.73e-11 Red blood cell count; LIHC cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg00166722 chr3:10149974 C3orf24 0.52 6.02 0.31 4.54e-9 Alzheimer's disease; LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg20607798 chr8:58055168 NA -0.63 -7.91 -0.39 3.52e-14 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs10221223 chr17:37489100 T/G cg07936489 chr17:37558343 FBXL20 0.81 13.01 0.58 9.99e-32 Glomerular filtration rate (creatinine); LIHC trans rs637571 0.565 rs570387 chr11:65637076 T/C cg17712092 chr4:129076599 LARP1B -0.69 -10.05 -0.48 5.22e-21 Eosinophil percentage of white cells; LIHC cis rs25645 0.760 rs11870683 chr17:38129841 T/A cg17344932 chr17:38183730 MED24;SNORD124 0.71 12.87 0.57 3.55e-31 Myeloid white cell count; LIHC cis rs9905704 0.647 rs8077332 chr17:57105223 A/G cg05425664 chr17:57184151 TRIM37 -0.42 -5.92 -0.31 7.63e-9 Testicular germ cell tumor; LIHC cis rs12887734 0.524 rs12588797 chr14:104300020 C/T cg01849466 chr14:104193079 ZFYVE21 0.38 5.77 0.3 1.76e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs6061231 0.958 rs2427305 chr20:60953749 G/C cg03945807 chr20:60948434 NA 0.44 6.81 0.35 4.32e-11 Colorectal cancer; LIHC cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg13395646 chr4:1353034 KIAA1530 -0.5 -8.33 -0.41 1.94e-15 Obesity-related traits; LIHC cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg13409248 chr3:40428643 ENTPD3 -0.43 -7.29 -0.37 2.2e-12 Renal cell carcinoma; LIHC cis rs17685 0.753 rs2302435 chr7:75676987 G/A cg01364799 chr7:75623366 TMEM120A 0.51 7.54 0.38 4.14e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg14709524 chr16:89940631 TCF25 0.58 7.41 0.37 1.02e-12 Skin colour saturation; LIHC cis rs6840360 0.571 rs875668 chr4:152525661 C/T cg22705602 chr4:152727874 NA -0.33 -6.26 -0.32 1.13e-9 Intelligence (multi-trait analysis); LIHC cis rs12928939 0.517 rs8050058 chr16:71981374 T/G cg03805757 chr16:71968109 PKD1L3 -0.92 -13.28 -0.58 9.33e-33 Post bronchodilator FEV1; LIHC cis rs7528419 1.000 rs629301 chr1:109818306 G/T cg00908766 chr1:109817496 CELSR2 0.48 8.91 0.43 3.06e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs12477438 0.666 rs10179910 chr2:99658503 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.49 -6.96 -0.35 1.7e-11 Chronic sinus infection; LIHC cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg00166722 chr3:10149974 C3orf24 0.48 5.75 0.3 2.01e-8 Alzheimer's disease; LIHC cis rs921968 0.541 rs6717433 chr2:219375711 G/C cg02985541 chr2:219472218 PLCD4 -0.42 -6.8 -0.35 4.61e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg03721293 chr16:90014378 DEF8 0.43 7.2 0.36 3.97e-12 Skin colour saturation; LIHC trans rs12386622 1.000 rs12386622 chr7:131853601 A/G cg17524136 chr11:84028382 DLG2 -0.5 -6.07 -0.31 3.39e-9 Homeostasis model assessment of beta-cell function (dietary factor interaction); LIHC cis rs4919087 0.851 rs3781373 chr10:99080585 C/T cg25902810 chr10:99078978 FRAT1 0.69 10.57 0.5 9.02e-23 Monocyte count; LIHC cis rs151997 0.962 rs27844 chr5:50190680 T/G cg06027927 chr5:50259733 NA 0.56 7.53 0.38 4.67e-13 Callous-unemotional behaviour; LIHC cis rs6543140 0.964 rs4851010 chr2:103056127 A/T cg09003973 chr2:102972529 NA -0.52 -5.85 -0.3 1.17e-8 Blood protein levels; LIHC cis rs9914988 0.943 rs28847895 chr17:27172520 T/C cg20469991 chr17:27169893 C17orf63 -0.54 -6.45 -0.33 3.76e-10 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg24209194 chr3:40518798 ZNF619 0.55 8.06 0.4 1.34e-14 Renal cell carcinoma; LIHC cis rs2645694 0.626 rs2703120 chr4:77822470 G/A cg06046430 chr4:77819534 ANKRD56 0.49 6.53 0.33 2.43e-10 Emphysema distribution in smoking; LIHC cis rs1211375 0.607 rs1203978 chr16:257211 A/C cg08400316 chr16:204221 HBZ -0.39 -6.14 -0.31 2.32e-9 Hematology traits;Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7116495 1.000 rs12272213 chr11:71816219 G/A cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg26116260 chr4:7069785 GRPEL1 1.01 18.91 0.71 4.28e-55 Monocyte percentage of white cells; LIHC cis rs1348850 0.526 rs935426 chr2:178369433 T/C cg27490568 chr2:178487706 NA 1.0 11.23 0.52 3.93e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2576037 0.544 rs629097 chr18:44378097 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.65 9.74 0.47 5.81e-20 Personality dimensions; LIHC cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg02290350 chr8:58132656 NA -0.5 -10.55 -0.5 1.01e-22 Developmental language disorder (linguistic errors); LIHC cis rs2067615 0.579 rs1922435 chr12:107082455 A/G cg15890332 chr12:107067104 RFX4 0.26 6.27 0.32 1.07e-9 Heart rate; LIHC cis rs7520050 0.966 rs7556615 chr1:46461369 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 6.02 0.31 4.5e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg03264133 chr6:25882463 NA -0.62 -7.5 -0.38 5.62e-13 Intelligence (multi-trait analysis); LIHC cis rs559928 0.597 rs947939 chr11:63885287 C/T cg02228329 chr11:64053129 BAD;GPR137 0.62 5.73 0.3 2.19e-8 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs28830936 1.000 rs12440747 chr15:42036690 G/A cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.75 -0.3 1.95e-8 Diastolic blood pressure; LIHC cis rs765787 0.530 rs2433228 chr15:45515371 A/C cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg22963979 chr7:1858916 MAD1L1 -0.44 -7.18 -0.36 4.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs1707322 0.685 rs28617418 chr1:46189526 T/A cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7674212 0.570 rs6810571 chr4:104086787 G/T cg16532752 chr4:104119610 CENPE -0.46 -7.22 -0.36 3.29e-12 Type 2 diabetes; LIHC cis rs4789452 0.509 rs2627208 chr17:75353102 A/G cg05865280 chr17:75406074 SEPT9 -0.33 -6.75 -0.34 6.25e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs35306767 0.903 rs12763396 chr10:927357 C/A cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs7078219 0.543 rs7095491 chr10:101274058 A/G cg06854084 chr10:101292507 NKX2-3 -0.34 -6.25 -0.32 1.23e-9 Dental caries; LIHC cis rs11148252 0.574 rs2038826 chr13:53280013 G/A cg12458913 chr13:53173898 NA 0.48 7.87 0.39 4.62e-14 Lewy body disease; LIHC cis rs155076 1.000 rs261432 chr13:21865915 G/C cg14456004 chr13:21872349 NA -1.14 -12.48 -0.56 1.02e-29 White matter hyperintensity burden; LIHC cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg26531700 chr6:26746687 NA 0.4 6.57 0.33 1.93e-10 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs11919350 chr3:134235970 G/C cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12477438 0.834 rs1563107 chr2:99701276 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.52 8.38 0.41 1.39e-15 Chronic sinus infection; LIHC cis rs11871801 1.000 rs12948909 chr17:40570602 A/C cg14558262 chr17:40713999 COASY 0.46 5.73 0.3 2.16e-8 Crohn's disease; LIHC cis rs58950470 0.887 rs1787034 chr11:65382564 A/G cg17120908 chr11:65337727 SSSCA1 -0.49 -5.9 -0.3 8.7e-9 Schizophrenia; LIHC cis rs1555399 0.836 rs7154258 chr14:67982254 G/T cg16224230 chr14:67978224 TMEM229B -0.24 -5.84 -0.3 1.25e-8 Parkinson's disease; LIHC cis rs72781680 0.752 rs56152044 chr2:23927680 A/G cg08917208 chr2:24149416 ATAD2B 0.99 8.28 0.41 2.8e-15 Lymphocyte counts; LIHC cis rs4474465 1.000 rs11237514 chr11:78180179 A/G cg27205649 chr11:78285834 NARS2 -0.39 -5.75 -0.3 1.94e-8 Alzheimer's disease (survival time); LIHC cis rs1707322 0.717 rs28752166 chr1:46213309 G/A cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6815814 0.861 rs1135430 chr4:38789361 T/C cg06935464 chr4:38784597 TLR10 0.53 8.98 0.44 1.84e-17 Breast cancer; LIHC cis rs798554 0.759 rs798495 chr7:2797267 T/C cg19346786 chr7:2764209 NA -0.47 -7.13 -0.36 6.09e-12 Height; LIHC cis rs7552404 1.000 rs72686191 chr1:76218319 G/T cg22875332 chr1:76189707 ACADM 0.46 6.53 0.33 2.38e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6089829 0.962 rs6011548 chr20:61666063 C/T cg08564027 chr20:61660810 NA 0.4 7.6 0.38 2.91e-13 Prostate cancer (SNP x SNP interaction); LIHC trans rs4927850 0.752 rs7618864 chr3:195749561 G/A cg16724585 chr3:197361211 NA -0.42 -6.15 -0.32 2.21e-9 Pancreatic cancer; LIHC cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg20090690 chr10:134436459 INPP5A -0.47 -6.08 -0.31 3.18e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2839186 0.843 rs17182671 chr21:47696238 T/C cg12379764 chr21:47803548 PCNT -0.61 -8.8 -0.43 7e-17 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs8048589 0.515 rs4780412 chr16:12232409 A/G cg02910054 chr16:12241554 SNX29 0.24 5.85 0.3 1.14e-8 Homeostasis model assessment of insulin resistance (dietary factor interaction);Fasting insulin (dietary factor interaction); LIHC cis rs875971 0.862 rs13226170 chr7:65999298 G/A cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.34e-9 Aortic root size; LIHC cis rs9300255 0.544 rs1716174 chr12:123660717 T/C cg00376283 chr12:123451042 ABCB9 0.58 5.72 0.3 2.3e-8 Neutrophil percentage of white cells; LIHC cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg13047869 chr3:10149882 C3orf24 0.52 6.63 0.34 1.33e-10 Alzheimer's disease; LIHC cis rs11583043 0.958 rs12746722 chr1:101464789 G/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.92 0.31 7.65e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4409675 0.576 rs6700473 chr1:28236682 C/T cg23691781 chr1:28212827 C1orf38 0.28 6.21 0.32 1.52e-9 Corneal astigmatism; LIHC cis rs3106136 0.546 rs4693003 chr4:95145469 A/G cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.32 -0.45 1.52e-18 Capecitabine sensitivity; LIHC cis rs244293 0.931 rs244297 chr17:53241700 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.17 -0.36 4.8e-12 Menarche (age at onset); LIHC cis rs6024905 0.565 rs6024991 chr20:36970167 C/G cg07053727 chr20:36965646 BPI -0.58 -10.88 -0.51 7.38e-24 Bipolar disorder and schizophrenia; LIHC trans rs75804782 0.641 rs11904390 chr2:239344663 T/A cg01134436 chr17:81009848 B3GNTL1 0.8 6.97 0.35 1.59e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs2404602 0.692 rs58889902 chr15:77173070 A/C cg03037974 chr15:76606532 NA 0.73 14.33 0.61 8.54e-37 Blood metabolite levels; LIHC cis rs116095464 0.558 rs59284383 chr5:284525 C/G cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs3796352 1.000 rs10510761 chr3:52965255 A/G cg07884673 chr3:53033167 SFMBT1 -0.84 -6.25 -0.32 1.23e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs992157 0.835 rs10932769 chr2:219147245 T/G cg00012203 chr2:219082015 ARPC2 -0.82 -13.05 -0.58 7.15e-32 Colorectal cancer; LIHC cis rs1953600 1.000 rs1953600 chr10:81911725 A/G cg04850286 chr10:81895943 PLAC9 0.34 5.99 0.31 5.3e-9 Sarcoidosis; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg18000306 chr6:288505 NA 0.35 6.35 0.32 6.7e-10 Menopause (age at onset); LIHC cis rs9513627 0.573 rs4771336 chr13:100210610 T/G cg15490075 chr13:100150979 NA 0.79 11.89 0.54 1.67e-27 Obesity-related traits; LIHC cis rs950776 0.518 rs12910289 chr15:78822065 T/G cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs589448 0.538 rs683790 chr12:69751434 T/G cg14784868 chr12:69753453 YEATS4 0.87 16.2 0.66 3.3e-44 Cerebrospinal fluid biomarker levels; LIHC cis rs1185460 0.967 rs1177562 chr11:118949331 C/T cg23280166 chr11:118938394 VPS11 0.57 7.57 0.38 3.47e-13 Coronary artery disease; LIHC trans rs208520 0.690 rs207740 chr6:66764132 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.8 9.11 0.44 7.24e-18 Exhaled nitric oxide output; LIHC cis rs7523273 0.526 rs2745975 chr1:208013620 C/T cg22525895 chr1:207977042 MIR29B2 -0.62 -10.11 -0.48 3.26e-21 Schizophrenia; LIHC cis rs2304069 0.954 rs4705409 chr5:149414899 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.94 12.03 0.55 5.05e-28 HIV-1 control; LIHC cis rs875971 1.000 rs7783613 chr7:65805261 C/T cg18252515 chr7:66147081 NA 0.41 5.78 0.3 1.71e-8 Aortic root size; LIHC cis rs2576037 0.523 rs590923 chr18:44404259 G/C cg19077165 chr18:44547161 KATNAL2 -0.47 -7.07 -0.36 8.66e-12 Personality dimensions; LIHC trans rs11098499 0.863 rs1383533 chr4:120434576 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.69 0.46 9.01e-20 Corneal astigmatism; LIHC cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg06481639 chr22:41940642 POLR3H -0.67 -6.9 -0.35 2.59e-11 Vitiligo; LIHC cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg26818010 chr10:134567672 INPP5A -0.7 -9.11 -0.44 7.05e-18 Migraine; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02283353 chr19:622406 POLRMT 0.43 6.51 0.33 2.66e-10 Immature fraction of reticulocytes; LIHC cis rs7582720 1.000 rs74421437 chr2:203831252 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7666738 0.830 rs13133355 chr4:98919415 A/G cg05340658 chr4:99064831 C4orf37 0.64 11.74 0.54 5.79e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs6546550 0.933 rs6546554 chr2:70135706 G/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC cis rs796364 1.000 rs10178177 chr2:200829993 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 8.12 0.4 8.79e-15 Schizophrenia; LIHC cis rs875971 0.929 rs12535036 chr7:65964063 G/T cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.54e-9 Aortic root size; LIHC cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg18867708 chr6:26865862 GUSBL1 -0.49 -7.5 -0.38 5.47e-13 Schizophrenia; LIHC cis rs3736594 0.513 rs56725354 chr2:27824168 G/C cg27432699 chr2:27873401 GPN1 0.46 6.92 0.35 2.29e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs1538970 0.924 rs11211117 chr1:45930246 C/T cg05343316 chr1:45956843 TESK2 0.58 8.5 0.42 5.77e-16 Platelet count; LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg24503407 chr1:205819492 PM20D1 0.73 10.66 0.5 4.23e-23 Menarche (age at onset); LIHC cis rs17095355 1.000 rs9630101 chr10:111738451 T/C cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.85 -0.3 1.18e-8 Biliary atresia; LIHC cis rs1577917 0.883 rs2660575 chr6:86684995 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.4 -7.15 -0.36 5.2e-12 Response to antipsychotic treatment; LIHC cis rs7246657 0.765 rs7247259 chr19:37851090 T/C cg23950597 chr19:37808831 NA -0.44 -5.97 -0.31 5.93e-9 Coronary artery calcification; LIHC cis rs763121 0.853 rs35565791 chr22:39063011 C/A cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs4718428 0.705 rs3800817 chr7:66263550 T/A cg18252515 chr7:66147081 NA -0.69 -9.5 -0.46 3.87e-19 Corneal structure; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs1538970 0.962 rs2153609 chr1:45814058 A/G cg24296786 chr1:45957014 TESK2 -0.48 -7.02 -0.36 1.17e-11 Platelet count; LIHC cis rs12602486 1.000 rs79296687 chr17:42262067 C/T cg08193365 chr17:42277699 NA 1.0 6.87 0.35 3.09e-11 Glycated hemoglobin levels; LIHC cis rs74233809 1.000 rs17094683 chr10:104851301 G/T cg03493300 chr10:104813866 CNNM2 0.46 6.29 0.32 9.93e-10 Birth weight; LIHC cis rs12701220 0.655 rs6463317 chr7:1159243 G/A cg18765753 chr7:1198926 ZFAND2A -0.41 -5.97 -0.31 5.95e-9 Bronchopulmonary dysplasia; LIHC cis rs2404602 0.647 rs11072628 chr15:77107761 C/A cg03037974 chr15:76606532 NA -0.6 -9.94 -0.47 1.27e-20 Blood metabolite levels; LIHC cis rs11792861 0.505 rs12377869 chr9:111907803 C/A cg05043794 chr9:111880884 C9orf5 -0.26 -6.73 -0.34 7.36e-11 Menarche (age at onset); LIHC cis rs8180040 0.701 rs62248439 chr3:46996448 A/G cg02527881 chr3:46936655 PTH1R 0.33 6.52 0.33 2.59e-10 Colorectal cancer; LIHC cis rs600806 0.778 rs2140923 chr1:110004990 C/T cg16275483 chr1:110013120 SYPL2 -0.52 -6.5 -0.33 2.81e-10 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg11060661 chr22:24314208 DDT;DDTL 0.62 10.8 0.5 1.37e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs763014 1.000 rs2269558 chr16:682250 C/T cg09263875 chr16:632152 PIGQ 0.59 10.36 0.49 4.87e-22 Height; LIHC cis rs6733011 0.578 rs11893888 chr2:99495239 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.44 -6.28 -0.32 1.01e-9 Bipolar disorder; LIHC cis rs965469 1.000 rs6139088 chr20:3329063 G/A cg25506879 chr20:3388711 C20orf194 -0.58 -6.98 -0.35 1.59e-11 IFN-related cytopenia; LIHC cis rs986417 0.818 rs1010051 chr14:61002988 G/C cg27398547 chr14:60952738 C14orf39 0.74 8.19 0.4 5.33e-15 Gut microbiota (bacterial taxa); LIHC cis rs4906332 1.000 rs12896919 chr14:103956713 T/C cg19000871 chr14:103996768 TRMT61A -0.46 -7.86 -0.39 5.04e-14 Coronary artery disease; LIHC cis rs6076065 0.630 rs2424558 chr20:23429344 A/G cg11657817 chr20:23433608 CST11 0.3 7.27 0.37 2.47e-12 Facial morphology (factor 15, philtrum width); LIHC cis rs35110281 0.627 rs6518268 chr21:44967448 A/G cg21573476 chr21:45109991 RRP1B -0.52 -9.7 -0.46 8.24e-20 Mean corpuscular volume; LIHC cis rs9457247 1.000 rs430097 chr6:167405073 A/G cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg11965913 chr1:205819406 PM20D1 0.63 9.24 0.45 2.71e-18 Menarche (age at onset); LIHC cis rs11958404 0.932 rs111802867 chr5:157424971 G/A cg05962755 chr5:157440814 NA 1.07 11.89 0.54 1.59e-27 IgG glycosylation; LIHC cis rs7617480 0.544 rs6442129 chr3:48735256 T/C cg07636037 chr3:49044803 WDR6 0.71 8.14 0.4 7.58e-15 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC trans rs9641123 0.639 rs2528528 chr7:93205096 T/C cg09745688 chr16:2908918 PRSS22 -0.37 -6.35 -0.32 6.73e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg05590025 chr7:65112418 INTS4L2 0.62 6.79 0.34 4.9e-11 Diabetic kidney disease; LIHC cis rs367615 0.679 rs4259216 chr5:108841817 A/G cg17395555 chr5:108820864 NA 0.4 8.56 0.42 3.9e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs6546550 0.901 rs13028508 chr2:70118427 A/T cg02498382 chr2:70120550 SNRNP27 0.44 7.38 0.37 1.18e-12 Prevalent atrial fibrillation; LIHC cis rs2072499 0.865 rs2758608 chr1:156202860 A/T cg24450063 chr1:156163899 SLC25A44 0.71 11.81 0.54 3.09e-27 Testicular germ cell tumor; LIHC cis rs72843506 0.586 rs74429763 chr17:19863519 G/C cg12065943 chr17:19881925 AKAP10 -0.39 -6.58 -0.34 1.78e-10 Schizophrenia; LIHC cis rs2574704 0.886 rs7638595 chr3:11635511 A/G cg15876825 chr3:11651881 VGLL4 -0.47 -7.59 -0.38 3.12e-13 Body mass index; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg24209194 chr3:40518798 ZNF619 -0.59 -9.12 -0.44 6.49e-18 Renal cell carcinoma; LIHC trans rs637571 0.544 rs500161 chr11:65695438 C/T cg17712092 chr4:129076599 LARP1B 0.81 14.22 0.61 2.16e-36 Eosinophil percentage of white cells; LIHC trans rs494453 0.538 rs2789544 chr1:112181963 G/A cg13908074 chr2:149259371 MBD5 -0.38 -6.05 -0.31 3.7e-9 Osteoporosis-related phenotypes; LIHC cis rs722599 0.683 rs8008475 chr14:75291900 C/T cg11812906 chr14:75593930 NEK9 0.43 6.58 0.34 1.81e-10 IgG glycosylation; LIHC cis rs7085104 0.513 rs619824 chr10:104581288 G/T cg15744005 chr10:104629667 AS3MT -0.41 -9.06 -0.44 1.02e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC trans rs801193 1.000 rs2286684 chr7:66129830 G/T cg26939375 chr7:64535504 NA -0.43 -6.8 -0.35 4.57e-11 Aortic root size; LIHC cis rs35883536 0.587 rs2809812 chr1:101032087 G/T cg14515779 chr1:101123966 NA -0.42 -5.95 -0.31 6.54e-9 Monocyte count; LIHC cis rs9916302 0.851 rs4390625 chr17:37620347 A/G cg00129232 chr17:37814104 STARD3 -0.41 -6.61 -0.34 1.45e-10 Glomerular filtration rate (creatinine); LIHC cis rs739401 0.611 rs494427 chr11:3048140 A/G cg08508325 chr11:3079039 CARS -0.33 -7.09 -0.36 7.52e-12 Longevity; LIHC cis rs9341808 0.718 rs2143887 chr6:80917287 T/C cg08355045 chr6:80787529 NA 0.36 7.52 0.38 4.81e-13 Sitting height ratio; LIHC cis rs7208859 0.623 rs7217984 chr17:29092766 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.12 0.4 8.8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11758351 1.000 rs77961951 chr6:26186075 A/G cg03854865 chr6:26224070 HIST1H3E 0.71 7.81 0.39 7.07e-14 Gout;Renal underexcretion gout; LIHC cis rs5769707 0.967 rs9616713 chr22:50049109 G/A cg07959070 chr22:50026188 C22orf34 -0.34 -8.71 -0.43 1.28e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs4319547 0.915 rs3803005 chr12:123110654 T/C cg23029597 chr12:123009494 RSRC2 -0.5 -7.08 -0.36 8.32e-12 Body mass index; LIHC cis rs344364 0.511 rs62040569 chr16:1948137 C/T cg26897989 chr16:1907736 C16orf73 -0.49 -6.23 -0.32 1.34e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs9640161 0.673 rs11773351 chr7:150030963 T/C cg17279839 chr7:150038598 RARRES2 0.59 11.96 0.54 8.98e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs972578 1.000 rs1569507 chr22:43356699 A/G cg01576275 chr22:43409880 NA 0.33 5.81 0.3 1.43e-8 Mean platelet volume; LIHC cis rs9649213 0.593 rs1468341 chr7:97987696 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.38 -6.07 -0.31 3.38e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs11105298 0.891 rs10858902 chr12:89927789 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.48 -0.37 6.4e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs11122272 0.603 rs2998427 chr1:231528112 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.28 0.45 2.04e-18 Hemoglobin concentration; LIHC cis rs597539 0.652 rs592697 chr11:68650064 G/A cg04772025 chr11:68637568 NA 0.44 5.9 0.3 8.89e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs11098499 0.691 rs10028773 chr4:120265259 C/G cg25214090 chr10:38739885 LOC399744 -0.45 -7.4 -0.37 1.1e-12 Corneal astigmatism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06812693 chr4:26323246 RBPJ 0.48 6.55 0.33 2.11e-10 Lung function (FEV1/FVC); LIHC cis rs769267 0.965 rs2017964 chr19:19387149 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs1018836 0.631 rs9987133 chr8:91470730 T/C cg16814680 chr8:91681699 NA -0.36 -5.88 -0.3 9.69e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs11098499 0.863 rs34868248 chr4:120442430 A/G cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs11608355 0.515 rs11613718 chr12:109912332 C/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs10089 0.953 rs1036171 chr5:127402798 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.92 0.35 2.21e-11 Ileal carcinoids; LIHC cis rs9486715 0.838 rs7452350 chr6:96883326 C/A cg06623918 chr6:96969491 KIAA0776 0.86 14.92 0.63 4.06e-39 Headache; LIHC cis rs11719291 0.831 rs11715177 chr3:48763894 G/A cg07636037 chr3:49044803 WDR6 -0.81 -7.88 -0.39 4.45e-14 Cognitive function; LIHC cis rs9467773 1.000 rs6932156 chr6:26571506 T/G cg11502198 chr6:26597334 ABT1 0.47 6.84 0.35 3.7e-11 Intelligence (multi-trait analysis); LIHC cis rs651907 0.535 rs11714444 chr3:101513682 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg12463550 chr7:65579703 CRCP -0.67 -6.97 -0.35 1.59e-11 Diabetic kidney disease; LIHC trans rs6489882 0.867 rs7134391 chr12:113366691 A/G cg10175203 chr3:128143634 NA -0.37 -6.12 -0.31 2.57e-9 Chronic lymphocytic leukemia; LIHC cis rs9811920 0.609 rs9817005 chr3:99682692 T/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.8 -0.3 1.48e-8 Axial length; LIHC cis rs7131987 0.621 rs57803026 chr12:29497506 G/A cg00204748 chr12:29376779 FAR2 0.38 6.82 0.35 4.1e-11 QT interval; LIHC cis rs875971 0.929 rs10950041 chr7:65973875 T/C cg18252515 chr7:66147081 NA -0.43 -6.02 -0.31 4.37e-9 Aortic root size; LIHC cis rs11122272 0.735 rs2808602 chr1:231537303 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.75e-22 Hemoglobin concentration; LIHC cis rs9486715 0.758 rs9386528 chr6:96928514 G/A cg06623918 chr6:96969491 KIAA0776 -0.81 -12.7 -0.57 1.6e-30 Headache; LIHC cis rs2153535 0.601 rs2327091 chr6:8540369 G/A cg23788917 chr6:8435910 SLC35B3 0.63 8.82 0.43 5.8e-17 Motion sickness; LIHC cis rs6138458 1.000 rs4273288 chr20:24900873 G/A cg26195577 chr20:24973756 C20orf3 -1.09 -13.71 -0.6 2.13e-34 Blood protein levels; LIHC trans rs208520 0.633 rs7738469 chr6:66807446 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.18 -0.44 4.33e-18 Exhaled nitric oxide output; LIHC cis rs7296418 0.961 rs1790094 chr12:123586688 T/C cg00376283 chr12:123451042 ABCB9 0.73 12.82 0.57 5.55e-31 Platelet count; LIHC cis rs1816752 0.905 rs6490929 chr13:25014252 G/A cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC cis rs858239 0.600 rs6956595 chr7:23134256 A/G cg23682824 chr7:23144976 KLHL7 0.4 6.08 0.31 3.27e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs507080 0.845 rs667982 chr11:118562767 T/C cg04173919 chr11:118528438 PHLDB1 0.34 6.34 0.32 7.14e-10 Serum metabolite levels; LIHC cis rs17817600 0.866 rs12283410 chr11:85641955 G/T cg03102841 chr11:85646010 NA 0.43 5.71 0.3 2.41e-8 Alzheimer's disease; LIHC trans rs36715 1.000 rs36705 chr5:127554486 A/G cg16011800 chr17:1958478 HIC1 -0.41 -6.08 -0.31 3.18e-9 Breast cancer; LIHC cis rs10751667 0.580 rs10751664 chr11:927077 T/G cg10932868 chr11:921992 NA 0.39 7.37 0.37 1.31e-12 Alzheimer's disease (late onset); LIHC cis rs9640161 0.659 rs59572505 chr7:150014986 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.44 -7.74 -0.39 1.16e-13 Blood protein levels;Circulating chemerin levels; LIHC trans rs950169 0.579 rs881983 chr15:84647308 C/T cg24036039 chr1:3397125 ARHGEF16 0.4 6.59 0.34 1.66e-10 Schizophrenia; LIHC cis rs7224685 0.608 rs17763551 chr17:3882309 C/T cg09695851 chr17:3907499 NA 0.48 5.74 0.3 2.1e-8 Type 2 diabetes; LIHC cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg23978390 chr7:1156363 C7orf50 0.6 9.33 0.45 1.36e-18 Longevity;Endometriosis; LIHC cis rs7503807 0.967 rs12947696 chr17:78596793 C/T cg09596252 chr17:78655493 RPTOR 0.4 7.08 0.36 8.33e-12 Obesity; LIHC cis rs4319547 0.728 rs61954974 chr12:123074169 T/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.13 -0.36 5.98e-12 Body mass index; LIHC cis rs9486715 1.000 rs2273621 chr6:97058553 A/G cg18709589 chr6:96969512 KIAA0776 -0.4 -6.81 -0.35 4.4e-11 Headache; LIHC cis rs11190604 1.000 rs3763695 chr10:102269206 A/G cg07080220 chr10:102295463 HIF1AN 0.57 8.29 0.41 2.58e-15 Palmitoleic acid (16:1n-7) levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02386183 chr20:13619553 TASP1 0.5 6.93 0.35 2.04e-11 Lung function (FEV1/FVC); LIHC cis rs1728785 1.000 rs1645927 chr16:68589300 T/G cg02972257 chr16:68554789 NA -0.53 -6.15 -0.32 2.19e-9 Ulcerative colitis; LIHC cis rs11676348 0.811 rs13027120 chr2:219020914 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.52 7.18 0.36 4.44e-12 Ulcerative colitis; LIHC cis rs208520 0.690 rs12189780 chr6:66759619 G/A cg07460842 chr6:66804631 NA 0.8 9.17 0.44 4.45e-18 Exhaled nitric oxide output; LIHC cis rs28830936 0.966 rs1531140 chr15:42125234 C/T cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.96 -0.31 6.37e-9 Diastolic blood pressure; LIHC cis rs7131987 0.650 rs10843377 chr12:29437053 C/G cg14222432 chr12:29376421 FAR2 -0.35 -6.52 -0.33 2.46e-10 QT interval; LIHC cis rs7572733 0.534 rs7557203 chr2:198795650 A/G cg00792783 chr2:198669748 PLCL1 0.45 6.62 0.34 1.4e-10 Dermatomyositis; LIHC cis rs1555399 0.967 rs1555397 chr14:67984540 G/A cg16224230 chr14:67978224 TMEM229B -0.24 -5.89 -0.3 9.23e-9 Parkinson's disease; LIHC cis rs72843506 0.722 rs16964352 chr17:20148408 A/G cg12065943 chr17:19881925 AKAP10 -0.31 -5.78 -0.3 1.66e-8 Schizophrenia; LIHC cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg06640241 chr16:89574553 SPG7 0.82 15.06 0.63 1.18e-39 Multiple myeloma (IgH translocation); LIHC cis rs9611565 0.649 rs6002480 chr22:42176917 A/T cg06634786 chr22:41940651 POLR3H -0.55 -5.8 -0.3 1.52e-8 Vitiligo; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03552398 chr14:89021307 PTPN21 -0.43 -6.09 -0.31 3.07e-9 Cognitive function; LIHC cis rs61677309 0.929 rs12576119 chr11:118158441 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs7937682 0.924 rs489783 chr11:111520522 A/G cg09085632 chr11:111637200 PPP2R1B -1.03 -12.38 -0.56 2.44e-29 Primary sclerosing cholangitis; LIHC cis rs7224737 1.000 rs7225608 chr17:40298326 G/A cg02228675 chr17:40259724 DHX58 -0.25 -5.77 -0.3 1.78e-8 Fibrinogen levels; LIHC cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.91 -0.3 8.45e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2708977 0.933 rs6576972 chr2:97152446 C/T cg01950434 chr2:97203154 ARID5A -0.43 -6.28 -0.32 1.04e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs7945718 0.622 rs4643058 chr11:12689454 C/T cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs7223966 1.000 rs8078462 chr17:61857937 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.76 0.34 5.99e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7103648 0.897 rs3758675 chr11:47400602 G/A cg20307385 chr11:47447363 PSMC3 0.85 12.32 0.55 4.17e-29 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs7617773 0.780 rs3731550 chr3:48206583 A/C cg11946769 chr3:48343235 NME6 0.88 10.87 0.51 7.55e-24 Coronary artery disease; LIHC cis rs8177179 0.967 rs6439436 chr3:133453779 C/T cg24879335 chr3:133465180 TF -0.46 -10.79 -0.5 1.49e-23 Iron status biomarkers (transferrin levels); LIHC cis rs2637266 1.000 rs7897061 chr10:78366776 C/T cg18941641 chr10:78392320 NA 0.28 5.89 0.3 9.12e-9 Pulmonary function; LIHC cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 11.52 0.53 3.59e-26 Alzheimer's disease; LIHC cis rs6690583 0.623 rs6700723 chr1:85514234 C/T cg22153463 chr1:85462885 MCOLN2 0.53 6.28 0.32 1.03e-9 Serum sulfate level; LIHC cis rs6747952 0.899 rs12731 chr2:239087912 G/A cg17459225 chr2:239074497 NA 0.36 5.81 0.3 1.46e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs9911578 0.757 rs8081906 chr17:56631907 A/T cg12560992 chr17:57184187 TRIM37 -0.76 -11.4 -0.52 9.78e-26 Intelligence (multi-trait analysis); LIHC cis rs6684514 1.000 rs59468948 chr1:156288058 A/T cg16558208 chr1:156270281 VHLL 0.55 10.39 0.49 3.56e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs7020830 0.858 rs67036212 chr9:37133538 A/G cg14294708 chr9:37120828 ZCCHC7 1.2 26.53 0.82 5.23e-85 Schizophrenia; LIHC cis rs1355223 0.902 rs12800220 chr11:34701617 A/G cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.12 -0.31 2.51e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9911578 1.000 rs4398153 chr17:56968181 T/C cg12560992 chr17:57184187 TRIM37 -0.98 -17.56 -0.69 1.2e-49 Intelligence (multi-trait analysis); LIHC cis rs8081395 0.899 rs2777898 chr17:57815608 G/C cg02344993 chr17:57696989 CLTC -0.45 -7.32 -0.37 1.73e-12 White blood cell count; LIHC cis rs727505 1.000 rs68007199 chr7:124491307 T/C cg23710748 chr7:124431027 NA -0.33 -5.82 -0.3 1.37e-8 Lewy body disease; LIHC cis rs1580019 0.844 rs4723159 chr7:32512804 T/C cg07520158 chr7:32535189 LSM5;AVL9 0.49 6.59 0.34 1.67e-10 Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12933314 chr7:4815160 KIAA0415 0.47 7.35 0.37 1.52e-12 Pancreatic cancer; LIHC cis rs5769765 0.862 rs9616392 chr22:50314705 G/A cg02269571 chr22:50332266 NA -0.75 -9.94 -0.47 1.29e-20 Schizophrenia; LIHC cis rs7726839 0.540 rs55929359 chr5:595956 C/G cg09021430 chr5:549028 NA -0.42 -8.36 -0.41 1.65e-15 Obesity-related traits; LIHC cis rs7095607 0.560 rs2673794 chr10:69926097 T/C cg18986048 chr10:69913749 MYPN 0.48 7.11 0.36 6.77e-12 Lung function (FVC); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17665931 chr19:38894173 FAM98C 0.5 6.61 0.34 1.46e-10 Lung function (FEV1/FVC); LIHC cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC cis rs3960554 0.529 rs1859795 chr7:75877354 A/G cg01364799 chr7:75623366 TMEM120A -0.46 -6.65 -0.34 1.16e-10 Eotaxin levels; LIHC cis rs7617773 0.780 rs4541431 chr3:48365218 G/C cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC cis rs11622475 0.677 rs59119562 chr14:104345703 C/T cg12183467 chr14:104352244 NA -0.45 -6.5 -0.33 2.9e-10 Bipolar disorder; LIHC cis rs903552 0.736 rs2132196 chr15:102007089 A/G cg04789225 chr15:102009795 PCSK6 -0.45 -5.99 -0.31 5.26e-9 Diabetic kidney disease; LIHC cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.87 0.51 7.94e-24 Platelet count; LIHC cis rs6430585 0.528 rs7573555 chr2:136694905 C/T cg07169764 chr2:136633963 MCM6 -1.24 -20.56 -0.74 1.01e-61 Corneal structure; LIHC cis rs4654899 0.733 rs6698440 chr1:21258712 C/T cg08539965 chr1:21396338 EIF4G3 0.34 5.99 0.31 5.32e-9 Superior frontal gyrus grey matter volume; LIHC cis rs6570726 0.620 rs12201226 chr6:145913419 A/T cg05347473 chr6:146136440 FBXO30 0.41 5.8 0.3 1.5e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs807669 0.527 rs11089259 chr22:19190143 C/T cg02655711 chr22:19163373 SLC25A1 0.36 6.07 0.31 3.46e-9 Metabolite levels; LIHC cis rs11641365 1.000 rs11641365 chr16:88773893 A/G cg00034003 chr16:88779146 CTU2 0.52 7.08 0.36 8.47e-12 Autism spectrum disorder-related traits; LIHC cis rs1008375 0.966 rs3796812 chr4:17582051 G/A cg02297831 chr4:17616191 MED28 0.48 7.24 0.36 3.08e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs992157 0.804 rs7559525 chr2:219150307 A/G cg00012203 chr2:219082015 ARPC2 -0.83 -13.21 -0.58 1.76e-32 Colorectal cancer; LIHC cis rs6964587 0.626 rs6972945 chr7:91549576 C/G cg17063962 chr7:91808500 NA -0.61 -11.03 -0.51 2.17e-24 Breast cancer; LIHC trans rs1728785 1.000 rs1170428 chr16:68603988 C/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.3 0.32 8.94e-10 Ulcerative colitis; LIHC cis rs2842992 0.830 rs2495279 chr6:160138796 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.54 9.56 0.46 2.49e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs317689 0.613 rs315112 chr12:69785926 T/A cg22834771 chr12:69754056 YEATS4 -0.46 -7.96 -0.4 2.48e-14 Response to diuretic therapy; LIHC cis rs6499255 1.000 rs4985518 chr16:69787158 T/C cg15192750 chr16:69999425 NA 0.46 7.04 0.36 1.09e-11 IgE levels; LIHC cis rs12497850 0.931 rs4974087 chr3:48919232 A/G cg07636037 chr3:49044803 WDR6 0.93 16.74 0.67 2.27e-46 Parkinson's disease; LIHC trans rs66887589 0.870 rs59590064 chr4:120539753 T/C cg25214090 chr10:38739885 LOC399744 -0.39 -6.24 -0.32 1.27e-9 Diastolic blood pressure; LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg00091569 chr3:40428383 ENTPD3 0.39 6.64 0.34 1.25e-10 Renal cell carcinoma; LIHC cis rs10751667 0.643 rs10902238 chr11:944810 G/A ch.11.42038R chr11:967971 AP2A2 0.53 9.72 0.47 7.06e-20 Alzheimer's disease (late onset); LIHC cis rs17106184 0.681 rs72902706 chr1:51212796 A/C cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC trans rs1005277 0.579 rs2008449 chr10:38414204 A/T cg23533926 chr12:111358616 MYL2 0.33 6.37 0.33 6.02e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.5 6.72 0.34 7.43e-11 Bipolar disorder; LIHC cis rs894734 0.535 rs2366143 chr12:54323256 G/A cg12374095 chr12:54320830 NA 0.45 6.77 0.34 5.55e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs4474465 1.000 rs7106080 chr11:78150592 G/A cg02023728 chr11:77925099 USP35 0.33 5.96 0.31 6.22e-9 Alzheimer's disease (survival time); LIHC trans rs11148252 0.875 rs4885953 chr13:52976491 G/A cg18335740 chr13:41363409 SLC25A15 0.35 6.16 0.32 2.1e-9 Lewy body disease; LIHC cis rs11122272 0.735 rs2486734 chr1:231531392 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg13607699 chr17:42295918 UBTF 0.45 7.05 0.36 1.02e-11 Total body bone mineral density; LIHC trans rs1499614 0.901 rs2178742 chr7:66197799 G/A cg07424592 chr7:64974309 NA 0.78 8.82 0.43 5.95e-17 Gout; LIHC cis rs66573146 0.831 rs73088564 chr4:6984553 G/C cg15105060 chr4:7024189 TBC1D14 -0.71 -6.0 -0.31 5.11e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs10193935 0.792 rs10204778 chr2:42498121 G/T cg27598129 chr2:42591480 NA -0.7 -10.51 -0.49 1.46e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs739401 0.611 rs7394974 chr11:3038868 C/T cg05729581 chr11:3078854 CARS -0.42 -5.81 -0.3 1.42e-8 Longevity; LIHC cis rs12220238 0.822 rs10824160 chr10:76132267 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC trans rs2243480 1.000 rs56985706 chr7:65394562 C/T cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs1801251 1.000 rs1446311 chr2:233705071 G/A cg08000102 chr2:233561755 GIGYF2 -0.76 -11.51 -0.53 3.76e-26 Coronary artery disease; LIHC trans rs2270927 0.510 rs67771044 chr5:75577819 A/G cg13563193 chr19:33072644 PDCD5 1.01 9.67 0.46 1.05e-19 Mean corpuscular volume; LIHC cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.06 0.55 3.69e-28 Prudent dietary pattern; LIHC cis rs8062405 0.755 rs62034350 chr16:28562256 A/G cg07382826 chr16:28625726 SULT1A1 0.49 7.68 0.38 1.74e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12291225 0.679 rs34238445 chr11:14315915 C/T cg19336497 chr11:14380999 RRAS2 -0.65 -12.8 -0.57 6.19e-31 Sense of smell; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg23049307 chr1:55353163 DHCR24 -0.45 -6.18 -0.32 1.83e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6088580 0.524 rs1321306 chr20:33266379 T/A cg07148914 chr20:33460835 GGT7 -0.51 -7.19 -0.36 4.11e-12 Glomerular filtration rate (creatinine); LIHC cis rs116095464 0.558 rs28636067 chr5:199415 G/A cg22857025 chr5:266934 NA -1.63 -16.04 -0.66 1.41e-43 Breast cancer; LIHC cis rs12908161 0.960 rs17599989 chr15:85285536 A/G cg17507749 chr15:85114479 UBE2QP1 0.63 7.3 0.37 2e-12 Schizophrenia; LIHC cis rs2522056 1.000 rs2706383 chr5:131792402 G/A cg24060327 chr5:131705240 SLC22A5 0.55 7.41 0.37 1.02e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs8081395 0.834 rs2665397 chr17:57826731 C/A cg13753209 chr17:57696993 CLTC -0.48 -7.3 -0.37 2.08e-12 White blood cell count; LIHC cis rs8014671 0.567 rs6573971 chr14:71011469 C/T cg25576086 chr14:70833871 SYNJ2BP 0.46 7.34 0.37 1.61e-12 Prostate cancer; LIHC cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg12042659 chr19:58951599 ZNF132 0.37 6.24 0.32 1.33e-9 Uric acid clearance; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg03188948 chr7:1209495 NA 0.49 6.99 0.35 1.41e-11 Longevity;Endometriosis; LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.63 0.46 1.38e-19 Height; LIHC cis rs8084351 0.577 rs4474758 chr18:50641829 G/A cg24270629 chr18:50823537 DCC 0.43 6.36 0.33 6.37e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg18252515 chr7:66147081 NA -1.3 -17.22 -0.68 2.59e-48 Diabetic kidney disease; LIHC cis rs35306767 0.855 rs55708963 chr10:925712 C/A cg20503657 chr10:835505 NA 1.32 14.2 0.61 2.75e-36 Eosinophil percentage of granulocytes; LIHC cis rs4845459 0.933 rs6700181 chr1:152593087 A/G cg20634798 chr1:152595351 LCE3A -0.31 -5.93 -0.31 7.34e-9 Psoriasis; LIHC cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg03264133 chr6:25882463 NA -0.44 -6.77 -0.34 5.59e-11 Height; LIHC cis rs9790314 1.000 rs6441373 chr3:161026717 T/G cg04691961 chr3:161091175 C3orf57 -0.4 -6.35 -0.32 6.7e-10 Morning vs. evening chronotype; LIHC cis rs798554 0.723 rs798518 chr7:2777825 A/G cg19717773 chr7:2847554 GNA12 -0.4 -6.54 -0.33 2.27e-10 Height; LIHC cis rs748404 0.587 rs690276 chr15:43704558 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.58 0.38 3.35e-13 Lung cancer; LIHC cis rs903552 1.000 rs12907048 chr15:102003873 G/T cg06707286 chr15:102010195 PCSK6 -0.43 -6.09 -0.31 3e-9 Diabetic kidney disease; LIHC cis rs67981189 0.593 rs221904 chr14:71599488 A/C cg15816911 chr14:71606274 NA -0.43 -6.95 -0.35 1.8e-11 Schizophrenia; LIHC cis rs10870270 1.000 rs10870232 chr10:133738537 T/G cg17892150 chr10:133769511 PPP2R2D -0.68 -12.89 -0.57 3.01e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7429990 0.870 rs13089844 chr3:48140231 G/A cg11946769 chr3:48343235 NME6 -0.47 -6.24 -0.32 1.28e-9 Educational attainment (years of education); LIHC cis rs9457247 0.765 rs4710171 chr6:167430186 A/G cg07741184 chr6:167504864 NA 0.32 7.34 0.37 1.55e-12 Crohn's disease; LIHC cis rs11608355 0.705 rs4766601 chr12:109890080 C/G cg04065206 chr12:109973212 UBE3B -0.46 -5.88 -0.3 9.61e-9 Neuroticism; LIHC cis rs4689592 0.503 rs56099074 chr4:7071259 A/G cg02503808 chr4:7069936 GRPEL1 -0.8 -10.86 -0.51 8.64e-24 Monocyte percentage of white cells; LIHC cis rs12497850 0.931 rs9835307 chr3:48857805 T/C cg07636037 chr3:49044803 WDR6 0.93 16.69 0.67 3.76e-46 Parkinson's disease; LIHC cis rs10242455 0.571 rs7805661 chr7:99171522 A/C cg18809830 chr7:99032528 PTCD1 -0.83 -6.67 -0.34 1e-10 Blood metabolite levels; LIHC cis rs2228479 0.850 rs2302162 chr16:89845287 A/G cg06558623 chr16:89946397 TCF25 0.86 11.54 0.53 3.03e-26 Skin colour saturation; LIHC cis rs57221529 0.766 rs72703064 chr5:587825 T/C cg09021430 chr5:549028 NA -0.44 -8.65 -0.42 1.97e-16 Lung disease severity in cystic fibrosis; LIHC cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg05368731 chr17:41323189 NBR1 0.74 12.37 0.56 2.74e-29 Menopause (age at onset); LIHC cis rs3820068 0.581 rs111699992 chr1:15927158 G/A cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg12064134 chr16:90016061 DEF8 0.42 5.83 0.3 1.27e-8 Skin colour saturation; LIHC cis rs7208859 0.673 rs28588622 chr17:29245699 G/A cg14067834 chr17:29058358 SUZ12P 0.63 6.29 0.32 9.82e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs3783890 0.887 rs12889783 chr14:93812850 C/T cg02802420 chr16:69363236 PDF;COG8 0.33 6.29 0.32 9.89e-10 Body mass index; LIHC cis rs12048904 0.595 rs2295280 chr1:101342497 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.82 13.77 0.6 1.23e-34 Multiple sclerosis; LIHC cis rs13108904 0.901 rs12641735 chr4:1304434 G/C cg13395646 chr4:1353034 KIAA1530 -0.45 -7.08 -0.36 8.26e-12 Obesity-related traits; LIHC cis rs2717559 0.522 rs35816096 chr8:143884938 C/T cg06565975 chr8:143823917 SLURP1 -0.39 -6.43 -0.33 4.31e-10 Urinary tract infection frequency; LIHC cis rs11955398 0.625 rs10939857 chr5:59956801 C/T cg02684056 chr5:59996105 DEPDC1B 0.42 5.94 0.31 7.18e-9 Intelligence (multi-trait analysis); LIHC cis rs8072100 0.807 rs2175290 chr17:45479917 C/A cg25173405 chr17:45401733 C17orf57 -0.41 -5.71 -0.3 2.45e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs9291683 0.588 rs2240722 chr4:10020757 A/G cg11266682 chr4:10021025 SLC2A9 0.34 7.29 0.37 2.23e-12 Bone mineral density; LIHC cis rs6582630 0.519 rs10880629 chr12:38533611 T/G cg26384229 chr12:38710491 ALG10B 0.71 9.96 0.47 1.11e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs3812831 0.695 rs7998546 chr13:114939914 C/G cg08824895 chr13:115047677 UPF3A 0.51 7.49 0.38 6.11e-13 Schizophrenia; LIHC cis rs7312933 0.524 rs11181465 chr12:42765098 T/G cg01256987 chr12:42539512 GXYLT1 -0.36 -5.97 -0.31 6.1e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs35110281 0.715 rs2838320 chr21:44995037 A/G cg04455712 chr21:45112962 RRP1B 0.5 8.44 0.41 9.43e-16 Mean corpuscular volume; LIHC cis rs10927875 0.632 rs2862162 chr1:16142960 A/C cg07117364 chr1:16154769 NA 0.4 7.01 0.35 1.31e-11 Dilated cardiomyopathy; LIHC cis rs9322817 0.691 rs7753202 chr6:105215289 T/C cg02098413 chr6:105308735 HACE1 -0.42 -7.54 -0.38 4.13e-13 Thyroid stimulating hormone; LIHC cis rs713477 0.967 rs10150617 chr14:55916225 A/C cg13175173 chr14:55914753 NA 0.34 7.94 0.39 2.91e-14 Pediatric bone mineral content (femoral neck); LIHC cis rs780096 0.526 rs7602534 chr2:27592423 C/T cg02592271 chr2:27665507 KRTCAP3 -0.42 -5.77 -0.3 1.82e-8 Total body bone mineral density; LIHC cis rs1577917 0.874 rs11756621 chr6:86740063 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -9.99 -0.48 8.58e-21 Response to antipsychotic treatment; LIHC cis rs6912958 0.559 rs2985039 chr6:88041757 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.11 0.36 6.65e-12 Monocyte percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25231972 chr10:31608136 ZEB1;LOC220930 0.45 6.17 0.32 1.93e-9 Lung function (FEV1/FVC); LIHC trans rs10838798 0.504 rs10838852 chr11:48286256 C/T cg15704280 chr7:45808275 SEPT13 -0.43 -6.42 -0.33 4.54e-10 Height; LIHC cis rs904251 0.828 rs1757174 chr6:37486695 G/A cg08126542 chr6:37504118 NA -0.39 -6.22 -0.32 1.47e-9 Cognitive performance; LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg25894440 chr7:65020034 NA -0.54 -6.13 -0.31 2.37e-9 Diabetic kidney disease; LIHC trans rs75804782 0.521 rs72993074 chr2:239413582 T/G cg01134436 chr17:81009848 B3GNTL1 0.78 6.71 0.34 8.12e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs1552244 0.882 rs13074282 chr3:10024699 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs6500602 0.727 rs3761681 chr16:4566857 C/T cg08645402 chr16:4508243 NA 0.44 8.1 0.4 9.53e-15 Schizophrenia; LIHC cis rs986417 1.000 rs1254287 chr14:60861774 C/T cg27398547 chr14:60952738 C14orf39 -0.78 -9.39 -0.45 8.39e-19 Gut microbiota (bacterial taxa); LIHC cis rs2274273 0.688 rs6573001 chr14:55556502 A/G cg01864836 chr14:55583639 NA -0.35 -6.65 -0.34 1.16e-10 Protein biomarker; LIHC cis rs4423214 0.570 rs7118246 chr11:71231124 G/C cg05163923 chr11:71159392 DHCR7 0.77 11.32 0.52 1.84e-25 Vitamin D levels; LIHC cis rs2836950 0.565 rs7276046 chr21:40581293 T/C cg06238570 chr21:40685208 BRWD1 -0.44 -7.11 -0.36 6.83e-12 Menarche (age at onset); LIHC cis rs9814567 1.000 rs1357762 chr3:134264859 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.65 -11.84 -0.54 2.4e-27 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13072611 chr3:133524485 SRPRB -0.5 -6.47 -0.33 3.4e-10 Systolic blood pressure; LIHC cis rs66569888 0.583 rs66529457 chr2:106727010 G/A cg16099169 chr2:106886729 NA -0.62 -6.76 -0.34 5.91e-11 Facial morphology (factor 23); LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg14671364 chr1:107599128 PRMT6 -0.53 -7.76 -0.39 9.78e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11628318 0.614 rs8010455 chr14:103164681 A/G cg23461800 chr14:103021989 NA 0.47 6.48 0.33 3.12e-10 Platelet count; LIHC cis rs45430 0.635 rs398800 chr21:42742212 A/C cg06102954 chr21:42741788 MX2 -0.39 -6.14 -0.32 2.31e-9 Melanoma; LIHC cis rs1559088 0.744 rs12972060 chr19:33537096 C/T cg27124370 chr19:33622961 WDR88 -0.42 -5.95 -0.31 6.81e-9 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7772486 0.655 rs2142981 chr6:146071695 G/C cg13319975 chr6:146136371 FBXO30 0.4 6.61 0.34 1.46e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4268898 0.662 rs72793208 chr2:24510284 C/T cg06627628 chr2:24431161 ITSN2 -0.72 -9.73 -0.47 6.57e-20 Asthma; LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC trans rs11039798 0.588 rs7108164 chr11:48626363 A/C cg15704280 chr7:45808275 SEPT13 0.57 6.41 0.33 4.77e-10 Axial length; LIHC cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.39 0.37 1.15e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs116095464 0.614 rs10059220 chr5:242813 C/T cg22496380 chr5:211416 CCDC127 -1.15 -10.76 -0.5 1.93e-23 Breast cancer; LIHC cis rs9902453 0.836 rs62070337 chr17:28466257 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.41 0.45 7.5e-19 Coffee consumption (cups per day); LIHC cis rs4803468 1.000 rs9304593 chr19:41942875 A/C cg09537434 chr19:41945824 ATP5SL 1.01 20.35 0.74 6.81e-61 Height; LIHC cis rs7493 0.755 rs2375001 chr7:94964640 A/T cg19678392 chr7:94953810 PON1 -0.45 -5.89 -0.3 8.99e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs5753037 0.653 rs131273 chr22:30153721 T/C cg01021169 chr22:30184971 ASCC2 -0.31 -5.75 -0.3 1.95e-8 Type 1 diabetes; LIHC cis rs9522267 0.535 rs12583489 chr13:112233455 G/A cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.757 rs1182171 chr7:2878510 A/G cg19717773 chr7:2847554 GNA12 -0.44 -6.82 -0.35 4.03e-11 Height; LIHC cis rs75908454 1.000 rs77432181 chr6:169990120 A/G cg19338460 chr6:170058176 WDR27 -0.89 -8.33 -0.41 1.94e-15 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs17331151 0.573 rs76029595 chr3:52868523 C/T cg04865290 chr3:52927548 TMEM110 -0.44 -6.51 -0.33 2.61e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs644799 0.931 rs496305 chr11:95567035 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.59 0.46 1.89e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2050392 0.517 rs656600 chr10:30765654 G/A cg25182066 chr10:30743637 MAP3K8 -0.64 -10.36 -0.49 4.56e-22 Inflammatory bowel disease; LIHC cis rs1878931 0.501 rs9635547 chr16:3416664 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.72 10.83 0.51 1.08e-23 Body mass index (adult); LIHC cis rs1843834 0.931 rs10170573 chr2:225552916 A/G cg22455342 chr2:225449267 CUL3 0.45 6.17 0.32 1.95e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs12928939 0.517 rs10852507 chr16:71971900 G/A cg03805757 chr16:71968109 PKD1L3 -0.94 -12.78 -0.57 7.61e-31 Post bronchodilator FEV1; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02792086 chr2:62684218 NA -0.43 -6.21 -0.32 1.54e-9 Pancreatic cancer; LIHC cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg09323728 chr8:95962352 TP53INP1 -0.3 -6.42 -0.33 4.5e-10 Type 2 diabetes; LIHC cis rs9916302 0.904 rs11078898 chr17:37536480 A/G cg03013999 chr17:37608204 MED1 -0.36 -5.97 -0.31 5.89e-9 Glomerular filtration rate (creatinine); LIHC trans rs2363709 0.892 rs2087553 chr3:67428164 G/A cg13681781 chr9:139102396 QSOX2 0.83 6.34 0.32 7.3e-10 IgE levels; LIHC cis rs6701037 0.782 rs12760073 chr1:175139295 G/T cg00958927 chr1:175162553 KIAA0040 -0.39 -6.25 -0.32 1.24e-9 Alcohol dependence; LIHC cis rs611744 0.967 rs695028 chr8:109239324 T/C cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs9467773 1.000 rs4713006 chr6:26519872 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.86 0.6 5.82e-35 Intelligence (multi-trait analysis); LIHC cis rs754466 0.874 rs61855849 chr10:79659934 G/A cg17075019 chr10:79541650 NA -0.62 -8.38 -0.41 1.39e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7607369 0.782 rs514799 chr2:219411203 A/G cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg03806693 chr22:41940476 POLR3H 1.08 12.81 0.57 6.14e-31 Vitiligo; LIHC cis rs523522 0.962 rs12814055 chr12:120987391 G/A cg27279351 chr12:120934652 DYNLL1 0.67 11.93 0.54 1.11e-27 High light scatter reticulocyte count; LIHC cis rs10508774 0.810 rs11008941 chr10:32733307 A/C cg01819863 chr10:32635814 EPC1 0.61 5.88 0.3 9.61e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6750047 0.567 rs336039 chr2:38258827 C/T cg07380506 chr2:38303506 CYP1B1 -0.52 -6.82 -0.35 4.25e-11 Cutaneous malignant melanoma;Melanoma; LIHC cis rs4728302 0.869 rs7779370 chr7:133595702 T/C cg10665199 chr7:133106180 EXOC4 0.37 6.54 0.33 2.24e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg03806693 chr22:41940476 POLR3H -1.03 -10.21 -0.48 1.56e-21 Vitiligo; LIHC cis rs3015497 0.554 rs8011039 chr14:51091267 C/T cg09863266 chr14:51125203 SAV1 -0.39 -6.26 -0.32 1.14e-9 Mean platelet volume; LIHC cis rs8017423 0.967 rs7158180 chr14:90729117 C/T cg04374321 chr14:90722782 PSMC1 0.78 15.26 0.64 1.75e-40 Mortality in heart failure; LIHC cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg24209194 chr3:40518798 ZNF619 0.45 6.6 0.34 1.55e-10 Renal cell carcinoma; LIHC cis rs17177078 0.558 rs8057788 chr16:24866174 C/T cg06028605 chr16:24865363 SLC5A11 0.45 6.48 0.33 3.29e-10 Type 2 diabetes (dietary heme iron intake interaction); LIHC cis rs807669 0.869 rs1061325 chr22:19184095 T/C cg02655711 chr22:19163373 SLC25A1 0.35 6.26 0.32 1.15e-9 Metabolite levels; LIHC cis rs12188164 0.561 rs2721010 chr5:456915 A/G cg26076054 chr5:421317 AHRR 0.27 5.89 0.3 9.05e-9 Cystic fibrosis severity; LIHC cis rs2404602 0.735 rs2454450 chr15:76831236 G/A cg23625390 chr15:77176239 SCAPER -0.5 -8.27 -0.41 3.08e-15 Blood metabolite levels; LIHC cis rs12497850 0.897 rs9884022 chr3:48956862 G/C cg06212747 chr3:49208901 KLHDC8B 0.56 7.22 0.36 3.44e-12 Parkinson's disease; LIHC cis rs12477438 1.000 rs6542873 chr2:99824965 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.98 -12.03 -0.55 4.74e-28 Chronic sinus infection; LIHC cis rs7072216 0.763 rs942803 chr10:100168631 G/T cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC trans rs3960554 0.569 rs10954750 chr7:75664921 C/G cg19862616 chr7:65841803 NCRNA00174 -0.88 -15.84 -0.65 9.2e-43 Eotaxin levels; LIHC cis rs7520050 0.966 rs6429582 chr1:46321843 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 -0.39 -5.88 -0.3 9.63e-9 Red blood cell count;Reticulocyte count; LIHC cis rs57244997 0.725 rs73030431 chr6:162439575 G/A cg17173639 chr6:162384350 PARK2 -0.52 -6.76 -0.34 5.88e-11 Mosquito bite size; LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg20295408 chr7:1910781 MAD1L1 -0.46 -6.84 -0.35 3.64e-11 Bipolar disorder and schizophrenia; LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg22907277 chr7:1156413 C7orf50 0.54 8.55 0.42 4.29e-16 Longevity;Endometriosis; LIHC cis rs77669868 0.866 rs3782023 chr11:114035516 G/C cg01914181 chr11:114070210 ZBTB16 0.6 7.36 0.37 1.42e-12 Monocyte percentage of white cells; LIHC cis rs743757 1.000 rs2236957 chr3:50440426 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.5 7.92 0.39 3.42e-14 Diastolic blood pressure; LIHC trans rs61931739 0.500 rs12832312 chr12:34031199 G/A cg26384229 chr12:38710491 ALG10B 0.53 7.3 0.37 2.04e-12 Morning vs. evening chronotype; LIHC trans rs1499614 0.831 rs3800822 chr7:66147149 A/G cg07424592 chr7:64974309 NA -0.77 -8.94 -0.44 2.49e-17 Gout; LIHC cis rs9929218 0.954 rs72785165 chr16:68755635 T/A cg01231543 chr16:68741748 NA 0.38 6.17 0.32 1.97e-9 Colorectal cancer; LIHC cis rs3820068 0.705 rs41270255 chr1:15892980 G/A cg17385448 chr1:15911702 AGMAT 0.41 6.8 0.35 4.65e-11 Systolic blood pressure; LIHC cis rs7772486 0.719 rs702307 chr6:145993454 C/G cg23711669 chr6:146136114 FBXO30 -0.73 -13.22 -0.58 1.59e-32 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.955 rs11931312 chr4:120159023 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.02 0.4 1.68e-14 Corneal astigmatism; LIHC cis rs9807989 0.507 rs4479442 chr2:103054074 A/T cg03938978 chr2:103052716 IL18RAP 0.3 5.87 0.3 1.06e-8 Asthma; LIHC cis rs7584330 0.868 rs67071074 chr2:238395429 T/C cg14458575 chr2:238380390 NA 0.44 6.77 0.34 5.65e-11 Prostate cancer; LIHC cis rs2836974 0.666 rs4624474 chr21:40686327 T/C cg11890956 chr21:40555474 PSMG1 -0.47 -7.59 -0.38 3.07e-13 Cognitive function; LIHC cis rs8078723 0.677 rs11658328 chr17:38149236 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.35 0.52 1.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg26818010 chr10:134567672 INPP5A -0.71 -9.07 -0.44 9.62e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12497850 0.865 rs13072911 chr3:48962128 T/G cg07636037 chr3:49044803 WDR6 0.92 16.41 0.66 4.62e-45 Parkinson's disease; LIHC cis rs10865541 0.902 rs13399186 chr2:3423201 G/T cg11642891 chr2:3452563 TTC15 -0.45 -7.2 -0.36 3.85e-12 Obesity-related traits; LIHC cis rs1669338 0.588 rs3846135 chr3:3195574 C/T cg16797762 chr3:3221439 CRBN -0.96 -8.77 -0.43 8.81e-17 White matter integrity; LIHC cis rs8084351 0.517 rs8088299 chr18:50556725 T/G cg24270629 chr18:50823537 DCC 0.41 6.21 0.32 1.52e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs6964587 1.000 rs2282974 chr7:91761617 G/A cg17063962 chr7:91808500 NA 1.02 19.69 0.73 3.16e-58 Breast cancer; LIHC cis rs28829049 0.597 rs2296107 chr1:19476649 C/G cg18202521 chr1:19600702 AKR7L -0.36 -6.33 -0.32 7.67e-10 QRS duration in Tripanosoma cruzi seropositivity; LIHC trans rs1005277 0.579 rs932538 chr10:38381314 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.37 -0.33 6.02e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg12751644 chr20:60527061 NA 0.36 5.9 0.3 8.9e-9 Body mass index; LIHC cis rs4638749 0.677 rs10189396 chr2:108829637 A/G cg25838818 chr2:108905173 SULT1C2 -0.4 -6.97 -0.35 1.68e-11 Blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25704407 chr19:1619401 TCF3 0.39 6.1 0.31 2.84e-9 Pancreatic cancer; LIHC cis rs11673344 0.864 rs55921822 chr19:37496812 C/T cg27390819 chr19:37464633 NA -0.54 -6.51 -0.33 2.6200000000000003e-10 Obesity-related traits; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg03321231 chr17:157219 RPH3AL 0.42 6.38 0.33 5.6e-10 Immature fraction of reticulocytes; LIHC cis rs2073499 1.000 rs78020607 chr3:50254624 A/G cg03645007 chr3:50255295 SLC38A3 0.47 6.33 0.32 7.66e-10 Schizophrenia; LIHC cis rs6570726 0.791 rs6902410 chr6:145905261 G/A cg13319975 chr6:146136371 FBXO30 -0.39 -6.25 -0.32 1.22e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10197940 0.624 rs3771901 chr2:152432481 G/A cg19508488 chr2:152266495 RIF1 0.53 7.61 0.38 2.76e-13 Lung cancer; LIHC cis rs3812111 0.774 rs493467 chr6:116429964 A/G cg08036074 chr6:116424633 NT5DC1 0.67 12.09 0.55 2.93e-28 Age-related macular degeneration; LIHC cis rs1419980 0.643 rs12229762 chr12:7776621 T/C cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.36e-8 HDL cholesterol levels; LIHC cis rs12477438 0.765 rs12470471 chr2:99689141 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.5 8.35 0.41 1.71e-15 Chronic sinus infection; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17520314 chr17:79604207 NPLOC4 -0.48 -7.04 -0.36 1.06e-11 Cognitive function; LIHC cis rs8180040 0.726 rs1463393 chr3:46994987 G/A cg16586182 chr3:47516702 SCAP 0.48 8.64 0.42 2.12e-16 Colorectal cancer; LIHC cis rs2303759 0.881 rs10412811 chr19:49884495 G/A cg22590775 chr19:49891494 CCDC155 0.47 7.72 0.39 1.34e-13 Multiple sclerosis; LIHC cis rs870825 0.616 rs7683537 chr4:185631998 T/C cg04058563 chr4:185651563 MLF1IP 0.7 7.36 0.37 1.36e-12 Blood protein levels; LIHC cis rs9309473 0.607 rs7604588 chr2:73571417 C/T cg20560298 chr2:73613845 ALMS1 -0.41 -6.42 -0.33 4.52e-10 Metabolite levels; LIHC cis rs11971779 0.680 rs11980313 chr7:139034643 C/G cg07862535 chr7:139043722 LUC7L2 0.58 10.12 0.48 3.07e-21 Diisocyanate-induced asthma; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg21635953 chr15:56538411 NA -0.45 -6.08 -0.31 3.24e-9 Longevity; LIHC trans rs3780486 0.874 rs10813955 chr9:33141791 C/T cg20290983 chr6:43655470 MRPS18A 1.18 30.71 0.86 2.55e-100 IgG glycosylation; LIHC cis rs9611565 0.559 rs13056262 chr22:42081921 A/G cg06634786 chr22:41940651 POLR3H 0.71 7.33 0.37 1.65e-12 Vitiligo; LIHC cis rs2153535 0.580 rs1414350 chr6:8472331 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs7613875 0.543 rs34034116 chr3:49959156 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.45 6.79 0.34 5.1e-11 Body mass index; LIHC trans rs561341 0.739 rs1978116 chr17:30220978 A/C cg20587970 chr11:113659929 NA -0.54 -6.98 -0.35 1.53e-11 Hip circumference adjusted for BMI; LIHC cis rs1387259 0.839 rs7487682 chr12:48579665 A/C cg21466736 chr12:48725269 NA 0.61 9.11 0.44 7.19e-18 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs7412746 0.611 rs66847267 chr1:150875173 C/A cg17724175 chr1:150552817 MCL1 0.37 7.35 0.37 1.52e-12 Melanoma; LIHC cis rs9303401 0.538 rs2240259 chr17:56458129 A/C cg25039879 chr17:56429692 SUPT4H1 0.79 8.89 0.43 3.57e-17 Cognitive test performance; LIHC cis rs507080 0.922 rs561845 chr11:118558827 A/G cg04173919 chr11:118528438 PHLDB1 0.35 6.56 0.33 2.01e-10 Serum metabolite levels; LIHC cis rs68170813 0.523 rs7781947 chr7:106902219 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs4650994 1.000 rs10798616 chr1:178515642 G/C cg05059571 chr16:84539110 KIAA1609 -0.38 -6.35 -0.32 6.9e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC cis rs6754311 0.550 rs12994270 chr2:136518103 T/A cg15123519 chr2:136567270 LCT 0.44 8.64 0.42 2.14e-16 Mosquito bite size; LIHC cis rs7662987 0.517 rs2602880 chr4:100040653 C/T cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs2404602 1.000 rs2404741 chr15:76851735 C/T cg03037974 chr15:76606532 NA 0.77 15.22 0.64 2.7e-40 Blood metabolite levels; LIHC cis rs2404602 0.574 rs4886795 chr15:76642218 G/C cg03037974 chr15:76606532 NA -0.55 -9.08 -0.44 8.77e-18 Blood metabolite levels; LIHC cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg03452623 chr4:187889614 NA 0.33 8.66 0.42 1.91e-16 Lobe attachment (rater-scored or self-reported); LIHC trans rs10506458 1.000 rs11174759 chr12:63444363 A/T cg22491629 chr6:157744540 C6orf35 -0.58 -10.11 -0.48 3.34e-21 Hemostatic factors and hematological phenotypes; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg20282741 chr1:53704012 MAGOH -0.41 -6.03 -0.31 4.14e-9 Eotaxin levels; LIHC cis rs6920364 1 rs6920364 chr6:167376466 G/C cg12798992 chr6:167411361 FGFR1OP -0.54 -8.28 -0.41 2.76e-15 Lung cancer; LIHC cis rs55702914 0.746 rs7588530 chr2:198146698 A/C cg10820045 chr2:198174542 NA -0.41 -6.22 -0.32 1.41e-9 Major depression and alcohol dependence; LIHC cis rs76419734 0.510 rs2544402 chr4:106687733 A/G cg24545054 chr4:106630052 GSTCD;INTS12 -0.67 -7.18 -0.36 4.29e-12 Post bronchodilator FEV1; LIHC cis rs5769707 0.706 rs2071903 chr22:50034517 G/A cg01652190 chr22:50026171 C22orf34 -0.35 -7.69 -0.38 1.58e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs4906332 1.000 rs12896919 chr14:103956713 T/C cg04998671 chr14:104000505 TRMT61A -0.46 -6.26 -0.32 1.17e-9 Coronary artery disease; LIHC cis rs6598955 0.670 rs11247892 chr1:26592727 A/G cg00852783 chr1:26633632 UBXN11 0.51 8.55 0.42 4.21e-16 Obesity-related traits; LIHC trans rs9940464 0.933 rs12597597 chr16:83367241 A/G cg13016115 chr14:23388406 RBM23 0.38 6.18 0.32 1.81e-9 Malaria; LIHC cis rs751728 1.000 rs9380378 chr6:33765479 T/C cg25922239 chr6:33757077 LEMD2 0.41 6.9 0.35 2.58e-11 Crohn's disease; LIHC cis rs4237845 0.680 rs10877033 chr12:58283731 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.47 6.64 0.34 1.22e-10 Intelligence (multi-trait analysis); LIHC cis rs1707322 1.000 rs785497 chr1:46591903 G/C cg06784218 chr1:46089804 CCDC17 -0.4 -7.22 -0.36 3.38e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6582630 0.555 rs56228141 chr12:38518652 T/G cg13010199 chr12:38710504 ALG10B 0.45 6.1 0.31 2.85e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7707921 0.881 rs12108833 chr5:81371755 A/G cg15871215 chr5:81402204 ATG10 -0.63 -6.26 -0.32 1.12e-9 Breast cancer; LIHC cis rs1008375 0.932 rs6449315 chr4:17590219 A/G cg16339924 chr4:17578868 LAP3 0.58 7.71 0.38 1.39e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg20887711 chr4:1340912 KIAA1530 0.49 7.14 0.36 5.65e-12 Longevity; LIHC cis rs6815814 0.731 rs10776482 chr4:38774785 A/G cg06935464 chr4:38784597 TLR10 0.38 5.94 0.31 7.12e-9 Breast cancer; LIHC cis rs2629540 0.889 rs17624662 chr10:126408146 A/C cg20435097 chr10:126320824 FAM53B -0.41 -5.98 -0.31 5.5e-9 Cocaine dependence; LIHC cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.54 -6.48 -0.33 3.25e-10 Diastolic blood pressure; LIHC cis rs1577917 0.572 rs911927 chr6:86327860 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.47 -9.17 -0.44 4.43e-18 Response to antipsychotic treatment; LIHC cis rs950169 0.922 rs11630760 chr15:85113337 G/T cg03959625 chr15:84868606 LOC388152 0.44 6.02 0.31 4.52e-9 Schizophrenia; LIHC cis rs757110 0.648 rs12146443 chr11:17384498 T/C cg15432903 chr11:17409602 KCNJ11 0.65 10.1 0.48 3.54e-21 Type 2 diabetes; LIHC cis rs11098499 0.908 rs12504149 chr4:120318577 G/A cg09307838 chr4:120376055 NA 0.76 11.65 0.53 1.25e-26 Corneal astigmatism; LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg02398342 chr17:80708632 TBCD;FN3K 0.63 10.34 0.49 5.67e-22 Glycated hemoglobin levels; LIHC cis rs986417 0.748 rs10142401 chr14:61039403 A/G cg27398547 chr14:60952738 C14orf39 0.56 6.85 0.35 3.34e-11 Gut microbiota (bacterial taxa); LIHC cis rs4523957 0.690 rs11078855 chr17:2091308 A/G cg16513277 chr17:2031491 SMG6 0.62 9.77 0.47 4.64e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg04267008 chr7:1944627 MAD1L1 -0.61 -9.56 -0.46 2.41e-19 Bipolar disorder and schizophrenia; LIHC cis rs34779708 0.931 rs17591135 chr10:35465190 T/A cg04310649 chr10:35416472 CREM -0.42 -5.75 -0.3 1.96e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17376456 1.000 rs9968749 chr5:93509559 A/G cg25358565 chr5:93447407 FAM172A 1.08 9.83 0.47 3.04e-20 Diabetic retinopathy; LIHC cis rs892961 0.932 rs6501954 chr17:75414398 G/C cg05865280 chr17:75406074 SEPT9 0.65 13.41 0.59 3.07e-33 Airflow obstruction; LIHC cis rs7666738 0.581 rs34205844 chr4:98887494 C/A cg05340658 chr4:99064831 C4orf37 0.65 11.73 0.54 6.4e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs7264396 0.563 rs2425111 chr20:34319765 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.47e-16 Total cholesterol levels; LIHC cis rs10751667 0.666 rs10902248 chr11:957742 A/G ch.11.42038R chr11:967971 AP2A2 0.56 10.09 0.48 4.1e-21 Alzheimer's disease (late onset); LIHC trans rs916888 0.687 rs199456 chr17:44797919 C/T cg16836995 chr17:43662488 NA -0.76 -7.8 -0.39 7.78e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg13393036 chr8:95962371 TP53INP1 -0.39 -8.85 -0.43 4.93e-17 Type 2 diabetes; LIHC cis rs5753037 0.653 rs140123 chr22:30143206 A/G cg01021169 chr22:30184971 ASCC2 0.32 5.92 0.3 7.73e-9 Type 1 diabetes; LIHC cis rs2050392 0.517 rs160017 chr10:30772894 A/G cg25182066 chr10:30743637 MAP3K8 -0.65 -10.51 -0.49 1.37e-22 Inflammatory bowel disease; LIHC cis rs9916302 0.861 rs33933929 chr17:37426441 A/C cg03013999 chr17:37608204 MED1 0.36 6.07 0.31 3.41e-9 Glomerular filtration rate (creatinine); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg18762849 chr10:81741832 NA -0.48 -6.07 -0.31 3.32e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs1577917 1.000 rs12201880 chr6:86627007 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs1005277 0.579 rs1740737 chr10:38499365 G/T cg03665457 chr10:38645376 HSD17B7P2 -0.45 -6.49 -0.33 3.09e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9393692 0.645 rs766407 chr6:26319534 T/C cg00631329 chr6:26305371 NA -0.5 -7.83 -0.39 6.21e-14 Educational attainment; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14935078 chr19:17414399 ABHD8 0.54 7.0 0.35 1.36e-11 Lung function (FEV1/FVC); LIHC cis rs748404 0.697 rs1095389 chr15:43566671 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.05 0.4 1.36e-14 Lung cancer; LIHC cis rs936229 0.749 rs7497201 chr15:75190690 A/G cg10253484 chr15:75165896 SCAMP2 -0.59 -6.93 -0.35 2.17e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg01646665 chr1:156251436 TMEM79;SMG5 0.31 5.91 0.3 8.15e-9 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs743757 0.938 rs2282753 chr3:50436716 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 0.54 8.54 0.42 4.53e-16 Diastolic blood pressure; LIHC cis rs12908161 1.000 rs11637142 chr15:85295927 A/G cg12863693 chr15:85201151 NMB 0.44 6.3 0.32 9.15e-10 Schizophrenia; LIHC cis rs3018712 0.532 rs948861 chr11:68420622 C/T cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.17e-8 Total body bone mineral density; LIHC cis rs912057 0.526 rs737449 chr6:6733729 A/G cg06612196 chr6:6737390 NA -0.49 -9.14 -0.44 5.66e-18 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC trans rs617791 0.508 rs10896074 chr11:65776304 C/T cg17712092 chr4:129076599 LARP1B -0.55 -6.68 -0.34 9.64e-11 Breast cancer; LIHC cis rs9814567 0.928 rs6768323 chr3:134268737 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs238295 0.631 rs6038205 chr20:5549073 T/A cg24001556 chr20:5591874 RP5-1022P6.2 -0.53 -7.19 -0.36 4.16e-12 Occipital cortical area (total cortical area interaction); LIHC cis rs55883249 1.000 rs55883249 chr2:9741535 C/A cg23886495 chr2:9695866 ADAM17 0.76 6.83 0.35 3.85e-11 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; LIHC cis rs4713118 0.869 rs6901520 chr6:27714575 G/T cg20933634 chr6:27740509 NA 0.48 6.27 0.32 1.09e-9 Parkinson's disease; LIHC cis rs9916302 0.904 rs10491128 chr17:37551988 G/A cg00129232 chr17:37814104 STARD3 0.41 6.49 0.33 2.95e-10 Glomerular filtration rate (creatinine); LIHC cis rs41997 1.000 rs1014268 chr7:118035388 A/C cg20597117 chr7:117824011 NAA38 -0.37 -5.96 -0.31 6.28e-9 Response to platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs7258465 0.931 rs7249020 chr19:18608147 A/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC cis rs8044995 0.563 rs61602448 chr16:68377520 C/T cg03983715 chr16:68378420 PRMT7 -0.5 -5.88 -0.3 9.57e-9 Schizophrenia; LIHC cis rs11997175 0.766 rs7387133 chr8:33727045 C/G ch.8.33884649F chr8:33765107 NA -0.32 -6.08 -0.31 3.14e-9 Body mass index; LIHC cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg10802521 chr3:52805072 NEK4 -0.44 -7.3 -0.37 2.05e-12 Bipolar disorder; LIHC cis rs1864585 0.806 rs17778223 chr8:10729692 A/T cg21756720 chr8:11724777 CTSB -0.5 -5.99 -0.31 5.21e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg11494091 chr17:61959527 GH2 0.45 8.09 0.4 1.05e-14 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg07677032 chr17:61819896 STRADA 0.43 6.18 0.32 1.79e-9 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.23 0.55 8.88e-29 Alzheimer's disease; LIHC cis rs8103278 1.000 rs7252126 chr19:46302374 T/A cg02376097 chr19:46275166 DMPK -0.45 -6.94 -0.35 1.96e-11 Coronary artery disease; LIHC cis rs933688 1.000 rs60513756 chr5:90727692 A/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.21 0.72 2.72e-56 Smoking behavior; LIHC cis rs7572733 0.514 rs770659 chr2:198669754 G/C cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.42e-11 Dermatomyositis; LIHC trans rs6600671 0.934 rs12060031 chr1:121243450 A/G cg09829573 chr1:144692074 NBPF9 0.43 7.19 0.36 4.08e-12 Hip geometry; LIHC cis rs9611519 0.964 rs4820428 chr22:41537589 C/T cg03806693 chr22:41940476 POLR3H 0.69 7.48 0.37 6.43e-13 Neuroticism; LIHC cis rs1461503 0.966 rs11218910 chr11:122842861 G/A cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs4319547 0.698 rs4039670 chr12:122822655 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.37 -0.37 1.32e-12 Body mass index; LIHC cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg09060608 chr5:178986726 RUFY1 -0.39 -5.94 -0.31 6.91e-9 Lung cancer; LIHC cis rs801193 1.000 rs1553610 chr7:66197233 T/C cg00343986 chr7:65444356 GUSB 0.41 6.1 0.31 2.86e-9 Aortic root size; LIHC trans rs7618501 0.602 rs2240327 chr3:50113034 C/T cg21659725 chr3:3221576 CRBN 0.68 11.08 0.51 1.36e-24 Intelligence (multi-trait analysis); LIHC cis rs853679 0.769 rs7752608 chr6:28301195 A/T cg01086810 chr6:28234912 ZNF187 0.95 6.35 0.32 6.88e-10 Depression; LIHC cis rs7116495 1.000 rs4945340 chr11:71619100 C/T cg26138937 chr11:71823887 C11orf51 -0.67 -6.87 -0.35 3e-11 Severe influenza A (H1N1) infection; LIHC cis rs600806 0.850 rs10858085 chr1:109914983 A/G cg23091122 chr1:110024289 SYPL2 -0.45 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC cis rs2274273 0.805 rs7159808 chr14:55624327 G/T cg01864836 chr14:55583639 NA -0.42 -8.26 -0.41 3.21e-15 Protein biomarker; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg14709524 chr16:89940631 TCF25 0.47 6.05 0.31 3.73e-9 Skin colour saturation; LIHC cis rs2760061 0.583 rs697763 chr1:228192622 G/C cg01200585 chr1:228362443 C1orf69 0.49 6.2 0.32 1.66e-9 Diastolic blood pressure; LIHC cis rs72781680 0.611 rs72797810 chr2:24336469 G/A cg06627628 chr2:24431161 ITSN2 -0.66 -7.74 -0.39 1.16e-13 Lymphocyte counts; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg16222790 chr8:144521374 ZC3H3 0.36 6.26 0.32 1.18e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1865721 0.682 rs7242637 chr18:73147492 A/C cg26385618 chr18:73139727 C18orf62 -0.28 -7.48 -0.38 6.16e-13 Intelligence; LIHC cis rs240764 0.725 rs7740826 chr6:101153665 A/G cg09795085 chr6:101329169 ASCC3 -0.47 -6.49 -0.33 2.98e-10 Neuroticism; LIHC cis rs6754311 0.593 rs1438305 chr2:136502792 C/G cg07305463 chr2:136567211 LCT 0.39 7.21 0.36 3.51e-12 Mosquito bite size; LIHC cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg11941060 chr3:133502564 NA -0.4 -5.98 -0.31 5.47e-9 Iron status biomarkers; LIHC cis rs798554 0.836 rs13243214 chr7:2817455 G/T cg19717773 chr7:2847554 GNA12 -0.4 -6.39 -0.33 5.5e-10 Height; LIHC cis rs8044995 0.568 rs112086775 chr16:68310917 A/C cg09835421 chr16:68378352 PRMT7 -0.62 -7.0 -0.35 1.35e-11 Schizophrenia; LIHC cis rs7100689 0.725 rs2487074 chr10:82064104 A/G cg01528321 chr10:82214614 TSPAN14 0.87 11.99 0.54 6.99e-28 Post bronchodilator FEV1; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15861578 chr12:56511939 ZC3H10 0.38 6.09 0.31 3.11e-9 Cognitive function; LIHC cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg27170947 chr2:26402098 FAM59B 0.66 8.34 0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs7264396 0.635 rs6058366 chr20:34512172 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -10.15 -0.48 2.54e-21 Total cholesterol levels; LIHC cis rs1775715 0.737 rs2799017 chr10:32203460 A/G cg14930904 chr10:32216787 ARHGAP12 0.33 5.76 0.3 1.88e-8 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg11062466 chr8:58055876 NA 0.51 6.46 0.33 3.53e-10 Developmental language disorder (linguistic errors); LIHC cis rs7727544 0.684 rs611084 chr5:131709739 A/C cg24060327 chr5:131705240 SLC22A5 0.59 8.58 0.42 3.33e-16 Blood metabolite levels; LIHC cis rs875971 0.838 rs2173570 chr7:65762963 T/A cg11764359 chr7:65958608 NA -0.92 -17.09 -0.68 9.37e-48 Aortic root size; LIHC cis rs12908161 1.000 rs35960805 chr15:85343980 T/G cg17507749 chr15:85114479 UBE2QP1 0.63 7.18 0.36 4.38e-12 Schizophrenia; LIHC cis rs10540 1.000 rs10540 chr11:494662 G/A cg03576123 chr11:487126 PTDSS2 -1.16 -8.65 -0.42 2.07e-16 Body mass index; LIHC cis rs1552244 0.882 rs112621205 chr3:10017916 G/A cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg20607798 chr8:58055168 NA 0.63 7.96 0.4 2.64e-14 Developmental language disorder (linguistic errors); LIHC cis rs10744422 1.000 rs2343108 chr12:123331301 C/T cg18912006 chr12:123335444 HIP1R -0.63 -7.59 -0.38 3.02e-13 Schizophrenia; LIHC cis rs2637266 0.935 rs1866890 chr10:78397073 C/T cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.24e-10 Pulmonary function; LIHC cis rs62229266 0.605 rs2835275 chr21:37460001 C/T cg12218747 chr21:37451666 NA -0.43 -7.02 -0.35 1.24e-11 Mitral valve prolapse; LIHC cis rs892961 0.777 rs747483 chr17:75412091 C/T cg05865280 chr17:75406074 SEPT9 0.65 13.52 0.59 1.16e-33 Airflow obstruction; LIHC cis rs7666738 0.753 rs6826709 chr4:98714553 C/G cg05340658 chr4:99064831 C4orf37 0.65 11.9 0.54 1.45e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs6089829 0.855 rs6090203 chr20:61663632 G/A cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC trans rs6489882 0.966 rs4238033 chr12:113378081 T/A cg10175203 chr3:128143634 NA 0.38 6.18 0.32 1.8e-9 Chronic lymphocytic leukemia; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg11494091 chr17:61959527 GH2 0.45 8.37 0.41 1.52e-15 Prudent dietary pattern; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs9583531 0.891 rs61969076 chr13:111391568 C/T cg24331049 chr13:111365604 ING1 -0.69 -9.16 -0.44 4.98e-18 Coronary artery disease; LIHC cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.66 0.34 1.09e-10 Bipolar disorder; LIHC cis rs8067354 0.681 rs9907923 chr17:57824927 C/T cg13753209 chr17:57696993 CLTC 0.73 11.52 0.53 3.71e-26 Hemoglobin concentration; LIHC cis rs10832963 1.000 rs7943121 chr11:18656062 G/C cg09201001 chr11:18656081 SPTY2D1 0.93 17.09 0.68 9.35e-48 Breast cancer; LIHC cis rs6977660 0.714 rs9969381 chr7:19827454 C/T cg07541023 chr7:19748670 TWISTNB 0.4 5.87 0.3 1.02e-8 Thyroid stimulating hormone; LIHC cis rs34779708 0.931 rs4934533 chr10:35359619 A/G cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.47e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2073300 1.000 rs34449811 chr20:23443771 T/C cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9596863 0.950 rs9568935 chr13:54397928 C/T ch.13.53330881F chr13:54432880 NA 0.43 5.74 0.3 2.08e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2120019 0.938 rs3850093 chr15:75318482 A/G cg17294928 chr15:75287854 SCAMP5 0.55 8.31 0.41 2.25e-15 Blood trace element (Zn levels); LIHC cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.55 8.93 0.43 2.6e-17 Schizophrenia; LIHC cis rs8016982 0.662 rs7148100 chr14:81678096 A/G cg01989461 chr14:81687754 GTF2A1 0.52 9.11 0.44 6.83e-18 Schizophrenia; LIHC cis rs7587476 1.000 rs3768707 chr2:215645135 C/T cg04004882 chr2:215674386 BARD1 0.49 6.65 0.34 1.19e-10 Neuroblastoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21271961 chr1:95285780 SLC44A3 0.4 6.12 0.31 2.62e-9 Cognitive function; LIHC cis rs11098499 0.954 rs12505469 chr4:120249585 C/T cg09307838 chr4:120376055 NA 0.75 11.48 0.53 4.88e-26 Corneal astigmatism; LIHC cis rs35110281 0.565 rs7278003 chr21:44966069 T/C cg21573476 chr21:45109991 RRP1B -0.55 -10.14 -0.48 2.68e-21 Mean corpuscular volume; LIHC trans rs10506458 1.000 rs1009539 chr12:63414655 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B 0.69 10.09 0.48 4.12e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs1198430 0.636 rs1009590 chr1:23823798 C/G cg19827787 chr1:23763612 ASAP3 -0.37 -6.07 -0.31 3.33e-9 Total cholesterol levels; LIHC cis rs116095464 0.558 rs112343653 chr5:257174 G/A cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20060523 chr4:142557759 IL15 0.45 6.26 0.32 1.17e-9 Lung function (FEV1/FVC); LIHC cis rs2455799 0.613 rs2246960 chr3:15717693 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.32 -0.37 1.84e-12 Mean platelet volume; LIHC cis rs483180 0.859 rs478093 chr1:120255126 C/T cg19096424 chr1:120255104 PHGDH -0.97 -13.12 -0.58 4.01e-32 Macular telangiectasia type 2; LIHC cis rs6938 0.534 rs8025447 chr15:75192222 T/G cg14664628 chr15:75095509 CSK -0.46 -6.5 -0.33 2.77e-10 Breast cancer; LIHC cis rs12220238 1.000 rs7096553 chr10:75957835 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.39 0.33 5.32e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs933688 1.000 rs6866191 chr5:90746852 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.37 0.66 6.82e-45 Smoking behavior; LIHC cis rs7131987 0.868 rs7958210 chr12:29395181 G/C cg21486233 chr12:29375141 FAR2 0.32 6.35 0.32 6.81e-10 QT interval; LIHC cis rs7845219 0.525 rs6471501 chr8:95922491 A/G cg13393036 chr8:95962371 TP53INP1 -0.31 -5.83 -0.3 1.28e-8 Type 2 diabetes; LIHC cis rs13191362 0.507 rs2849525 chr6:163126652 A/C cg06582575 chr6:163149167 PACRG;PARK2 -0.52 -6.0 -0.31 5.11e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 6.15 0.32 2.13e-9 Bipolar disorder; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs7767780 chr6:8453462 A/G cg21535247 chr6:8435926 SLC35B3 0.63 8.43 0.41 9.78e-16 Motion sickness; LIHC trans rs916888 0.773 rs199447 chr17:44812188 C/T cg22968622 chr17:43663579 NA 1.18 13.01 0.58 1.02e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9457247 0.967 rs2149092 chr6:167372978 C/T cg23791538 chr6:167370224 RNASET2 0.68 11.67 0.53 9.94e-27 Crohn's disease; LIHC cis rs754466 0.561 rs11002343 chr10:79705871 G/A cg17075019 chr10:79541650 NA -0.53 -5.93 -0.31 7.28e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3008870 0.755 rs2815381 chr1:67514591 G/A cg02640540 chr1:67518911 SLC35D1 0.67 12.59 0.56 3.91e-30 Lymphocyte percentage of white cells; LIHC cis rs7927771 0.864 rs7107726 chr11:47429245 T/A cg20307385 chr11:47447363 PSMC3 -0.48 -6.28 -0.32 1.03e-9 Subjective well-being; LIHC cis rs6500602 0.701 rs4785968 chr16:4535307 T/A cg08645402 chr16:4508243 NA 0.39 7.31 0.37 1.88e-12 Schizophrenia; LIHC cis rs7772486 0.790 rs1062067 chr6:146207563 A/G cg23711669 chr6:146136114 FBXO30 0.64 11.1 0.51 1.21e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs4129767 0.647 rs1976703 chr17:76401328 C/T cg20026190 chr17:76395443 PGS1 0.4 5.93 0.31 7.44e-9 HDL cholesterol; LIHC cis rs4819052 1.000 rs9984901 chr21:46663952 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 9.67 0.46 1.02e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7264396 0.790 rs2295355 chr20:34252654 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.32 -0.52 1.88e-25 Total cholesterol levels; LIHC cis rs12579753 0.956 rs34747993 chr12:82217777 C/T cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.48e-9 Resting heart rate; LIHC trans rs2727020 0.634 rs11040331 chr11:49345726 T/C cg15704280 chr7:45808275 SEPT13 -0.73 -10.43 -0.49 2.72e-22 Coronary artery disease; LIHC cis rs600806 0.713 rs11102984 chr1:109997373 T/C cg23091122 chr1:110024289 SYPL2 -0.52 -6.93 -0.35 2.04e-11 Intelligence (multi-trait analysis); LIHC cis rs288342 0.832 rs288241 chr2:183643905 A/T cg02625481 chr2:183667124 NA -0.29 -6.06 -0.31 3.52e-9 Recurrent major depressive disorder; LIHC cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg06238570 chr21:40685208 BRWD1 0.58 6.86 0.35 3.33e-11 Cognitive function; LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.11 0.55 2.38e-28 Height; LIHC cis rs8060686 0.641 rs75297764 chr16:68212820 C/T cg05110241 chr16:68378359 PRMT7 -0.57 -6.52 -0.33 2.47e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs4638749 0.677 rs6713634 chr2:108827907 T/G cg06795125 chr2:108905320 SULT1C2 -0.31 -6.04 -0.31 3.92e-9 Blood pressure; LIHC cis rs9612 0.950 rs11351 chr19:44271066 A/C cg08581076 chr19:44259116 C19orf61 0.6 7.44 0.37 8.04e-13 Exhaled nitric oxide output; LIHC cis rs9783347 0.925 rs3802968 chr11:18343878 A/G cg15585147 chr11:18324498 HPS5 0.43 6.65 0.34 1.18e-10 Pancreatic cancer; LIHC cis rs72781680 1.000 rs72796351 chr2:24158425 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.77 0.39 9.29e-14 Lymphocyte counts; LIHC cis rs2795502 1.000 rs2795496 chr10:43337842 G/A cg20628663 chr10:43360327 NA -0.46 -7.09 -0.36 7.64e-12 Blood protein levels; LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg18306943 chr3:40428807 ENTPD3 -0.43 -7.57 -0.38 3.56e-13 Renal cell carcinoma; LIHC cis rs2760061 0.626 rs594916 chr1:228133544 C/A cg01200585 chr1:228362443 C1orf69 -0.39 -5.79 -0.3 1.59e-8 Diastolic blood pressure; LIHC trans rs8073060 0.586 rs17638867 chr17:34052513 C/T cg19694781 chr19:47549865 TMEM160 1.2 12.67 0.57 1.95e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs4654899 1.000 rs2271115 chr1:21295864 C/T cg08539965 chr1:21396338 EIF4G3 0.34 5.96 0.31 6.37e-9 Superior frontal gyrus grey matter volume; LIHC cis rs3096299 0.606 rs4785573 chr16:89565403 A/G cg02187348 chr16:89574699 SPG7 0.46 6.33 0.32 7.56e-10 Multiple myeloma (IgH translocation); LIHC cis rs644799 0.965 rs10831430 chr11:95509638 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.13 0.68 5.98e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2303759 0.918 rs1054770 chr19:49878115 G/A cg22590775 chr19:49891494 CCDC155 0.47 7.72 0.39 1.33e-13 Multiple sclerosis; LIHC cis rs2952156 0.920 rs2517959 chr17:37846512 A/T cg00129232 chr17:37814104 STARD3 -0.53 -9.58 -0.46 2.11e-19 Asthma; LIHC cis rs7715806 0.509 rs34349 chr5:74944868 A/G cg08253296 chr5:74907592 NA -0.53 -6.49 -0.33 2.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7959452 0.535 rs10878953 chr12:69674187 A/G cg20891283 chr12:69753455 YEATS4 0.77 14.32 0.61 9.17e-37 Blood protein levels; LIHC cis rs11190604 0.943 rs11190588 chr10:102273565 C/T cg07080220 chr10:102295463 HIF1AN 0.56 8.06 0.4 1.3e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2816062 0.786 rs2745316 chr1:18896830 G/A cg18795169 chr1:18902165 NA -0.79 -17.68 -0.69 3.98e-50 Urate levels in lean individuals; LIHC cis rs2050392 1.000 rs2265186 chr10:30691743 C/T cg25182066 chr10:30743637 MAP3K8 0.43 7.01 0.35 1.3e-11 Inflammatory bowel disease; LIHC cis rs10785877 0.570 rs7043538 chr9:137109051 A/G cg21243944 chr9:137118148 NA 0.46 6.52 0.33 2.51e-10 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs9596863 0.750 rs1971924 chr13:54432432 T/G ch.13.53330881F chr13:54432880 NA -0.44 -6.17 -0.32 1.89e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs4453791 0.932 rs13073816 chr3:38915346 A/T cg02254461 chr3:39195904 CSRNP1 0.66 5.89 0.3 9.44e-9 Social communication problems; LIHC cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg17971929 chr21:40555470 PSMG1 -0.43 -6.47 -0.33 3.35e-10 Cognitive function; LIHC cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg21448741 chr8:58168803 NA 0.34 6.13 0.31 2.42e-9 Developmental language disorder (linguistic errors); LIHC cis rs3020736 0.500 rs6002614 chr22:42501802 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs12368653 0.666 rs799265 chr12:58112189 A/G cg12615879 chr12:58013172 SLC26A10 0.34 6.83 0.35 3.83e-11 Multiple sclerosis; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg15248135 chr19:56154954 ZNF581 -0.45 -6.2 -0.32 1.66e-9 Alopecia areata; LIHC cis rs2629540 0.847 rs12762597 chr10:126387043 G/A cg20435097 chr10:126320824 FAM53B -0.42 -6.25 -0.32 1.21e-9 Cocaine dependence; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06385459 chr4:82393184 RASGEF1B 0.47 6.6 0.34 1.53e-10 Lung function (FEV1/FVC); LIHC cis rs9309473 0.583 rs6546822 chr2:73575098 G/A cg20560298 chr2:73613845 ALMS1 -0.43 -6.99 -0.35 1.46e-11 Metabolite levels; LIHC cis rs332507 0.830 rs3821532 chr3:124402618 G/T cg05980111 chr3:124395277 KALRN 0.43 6.71 0.34 7.85e-11 Plateletcrit; LIHC cis rs2370759 1.000 rs77165999 chr10:32577131 T/C cg18270830 chr10:32634957 EPC1 0.53 6.44 0.33 4.04e-10 Sexual dysfunction (female); LIHC trans rs6952808 0.689 rs12668156 chr7:2019875 G/A cg04565464 chr8:145669602 NFKBIL2 0.42 7.08 0.36 8.4e-12 Bipolar disorder and schizophrenia; LIHC cis rs11663156 0.880 rs1502219 chr18:51054889 C/T cg24270629 chr18:50823537 DCC -0.5 -7.01 -0.35 1.32e-11 Intelligence (multi-trait analysis); LIHC cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.87 8.23 0.41 4.09e-15 Platelet count; LIHC cis rs9902453 1.000 rs60967688 chr17:28437052 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.7 0.46 7.95e-20 Coffee consumption (cups per day); LIHC cis rs2070488 1.000 rs13079757 chr3:38491444 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC trans rs911555 0.755 rs8010247 chr14:103933556 A/G cg17675199 chr6:35436792 RPL10A -0.44 -9.2 -0.45 3.51e-18 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg00684032 chr4:1343700 KIAA1530 0.51 7.35 0.37 1.5e-12 Obesity-related traits; LIHC cis rs6565681 0.943 rs6565683 chr17:78362300 A/T cg15383979 chr17:78362278 RNF213;LOC100294362 -0.53 -7.55 -0.38 3.92e-13 Moyamoya disease; LIHC cis rs6502050 0.731 rs9891378 chr17:80116035 T/C cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.68e-9 Life satisfaction; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg07047601 chr22:21337040 LZTR1 -0.46 -7.06 -0.36 9.08e-12 Triglycerides; LIHC cis rs801193 0.844 rs732465 chr7:65998450 T/C cg11764359 chr7:65958608 NA 0.63 9.53 0.46 3.08e-19 Aortic root size; LIHC cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg25072359 chr17:41440525 NA 0.37 5.99 0.31 5.46e-9 Menopause (age at onset); LIHC cis rs6714710 0.603 rs12104810 chr2:98443658 C/T cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs11628318 0.614 rs10782496 chr14:103079725 C/G cg01864069 chr14:103024347 NA -0.34 -5.85 -0.3 1.14e-8 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13662262 chr21:30364895 RNF160 0.49 7.2 0.36 3.8e-12 Cognitive function; LIHC cis rs2976388 0.647 rs2164307 chr8:143788831 A/T cg06565975 chr8:143823917 SLURP1 0.34 6.29 0.32 9.53e-10 Urinary tract infection frequency; LIHC cis rs763121 0.962 rs909564 chr22:39126508 A/G cg14440974 chr22:39074834 NA -0.34 -5.75 -0.3 1.95e-8 Menopause (age at onset); LIHC cis rs2976388 1.000 rs1045605 chr8:143764101 C/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.21e-9 Urinary tract infection frequency; LIHC cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg04083430 chr16:4736063 MGRN1 -0.42 -5.78 -0.3 1.64e-8 Schizophrenia; LIHC cis rs1144333 1.000 rs17097836 chr1:76462006 T/A cg22875332 chr1:76189707 ACADM 0.4 6.24 0.32 1.26e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs831571 0.668 rs17069879 chr3:64083417 A/G cg16258503 chr3:63850278 ATXN7;THOC7 0.54 6.44 0.33 3.96e-10 Type 2 diabetes; LIHC trans rs916888 0.773 rs199457 chr17:44795469 C/T cg22968622 chr17:43663579 NA 1.19 13.18 0.58 2.28e-32 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs11025559 0.716 rs1596376 chr11:20454229 T/C cg19653624 chr11:20408972 PRMT3 -0.48 -6.2 -0.32 1.67e-9 Pursuit maintenance gain; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13072611 chr3:133524485 SRPRB -0.44 -6.14 -0.32 2.3e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2839186 0.504 rs11702278 chr21:47936295 T/G cg12379764 chr21:47803548 PCNT 0.72 12.0 0.54 6.21e-28 Testicular germ cell tumor; LIHC cis rs11229555 0.645 rs11530830 chr11:58252992 C/G cg15696309 chr11:58395628 NA 0.63 7.36 0.37 1.4e-12 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1506636 0.924 rs4370458 chr7:123260968 G/A cg03229431 chr7:123269106 ASB15 -0.59 -12.16 -0.55 1.62e-28 Plateletcrit;Platelet count; LIHC cis rs56235845 0.694 rs12055081 chr5:176757191 C/T cg17509989 chr5:176798049 RGS14 0.6 7.73 0.39 1.21e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs6952808 0.609 rs12699453 chr7:1953056 C/T cg14004847 chr7:1930337 MAD1L1 -0.55 -8.17 -0.4 6.07e-15 Bipolar disorder and schizophrenia; LIHC cis rs8177253 0.507 rs4241357 chr3:133475563 A/C cg24879335 chr3:133465180 TF -0.35 -7.7 -0.38 1.5e-13 Iron status biomarkers; LIHC cis rs703842 0.642 rs10876994 chr12:58064737 A/C cg04478727 chr12:58166393 METTL1;FAM119B 0.55 7.52 0.38 4.88e-13 Multiple sclerosis; LIHC cis rs881375 0.715 rs10760119 chr9:123646060 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.41 6.13 0.31 2.48e-9 Rheumatoid arthritis; LIHC cis rs992157 0.835 rs7559416 chr2:219150211 A/G cg00012203 chr2:219082015 ARPC2 -0.85 -13.43 -0.59 2.66e-33 Colorectal cancer; LIHC cis rs67460515 0.892 rs34016896 chr3:160992864 C/T cg03342759 chr3:160939853 NMD3 -0.66 -9.89 -0.47 1.91e-20 Parkinson's disease; LIHC trans rs6489882 0.966 rs7980275 chr12:113380529 T/A cg10175203 chr3:128143634 NA 0.38 6.2 0.32 1.67e-9 Chronic lymphocytic leukemia; LIHC cis rs9733 0.596 rs7549795 chr1:150656873 G/A cg17724175 chr1:150552817 MCL1 0.48 9.54 0.46 2.86e-19 Tonsillectomy; LIHC cis rs9790314 0.905 rs7633186 chr3:161003124 A/G cg03342759 chr3:160939853 NMD3 -0.72 -9.34 -0.45 1.29e-18 Morning vs. evening chronotype; LIHC cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg23758822 chr17:41437982 NA 0.91 16.84 0.67 8.86e-47 Menopause (age at onset); LIHC cis rs7107174 1.000 rs2450131 chr11:77944568 A/C cg02023728 chr11:77925099 USP35 0.46 8.52 0.42 5.25e-16 Testicular germ cell tumor; LIHC cis rs17376456 0.825 rs35426871 chr5:93291613 C/T cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.76 0.3 1.83e-8 Menopause (age at onset); LIHC cis rs7095944 0.614 rs1055256 chr10:126446592 A/G cg08799069 chr10:126477246 METTL10 -0.38 -6.72 -0.34 7.81e-11 Asthma; LIHC cis rs9916302 0.904 rs679995 chr17:37441679 A/T cg00129232 chr17:37814104 STARD3 0.38 6.08 0.31 3.25e-9 Glomerular filtration rate (creatinine); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23623486 chr14:32030546 NUBPL 0.45 6.24 0.32 1.31e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg25897951 chr4:1244024 CTBP1;C4orf42 -0.42 -6.1 -0.31 2.8e-9 Longevity; LIHC cis rs11673344 0.864 rs11667146 chr19:37495395 G/A cg27390819 chr19:37464633 NA -0.54 -6.52 -0.33 2.56e-10 Obesity-related traits; LIHC cis rs9611519 0.929 rs9611474 chr22:41434858 G/A cg03806693 chr22:41940476 POLR3H -0.69 -7.78 -0.39 8.93e-14 Neuroticism; LIHC cis rs8177179 0.967 rs9820225 chr3:133449189 A/G cg18769074 chr3:133464867 TF 0.27 6.09 0.31 3.02e-9 Iron status biomarkers (transferrin levels); LIHC cis rs3736594 0.546 rs6719960 chr2:27830067 C/T cg27432699 chr2:27873401 GPN1 -0.45 -6.75 -0.34 6.32e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs10779751 0.770 rs6701524 chr1:11198502 A/G cg08854313 chr1:11322531 MTOR -0.79 -10.6 -0.5 6.64e-23 Body mass index; LIHC cis rs8072100 0.688 rs12602134 chr17:45582136 C/G cg08085267 chr17:45401833 C17orf57 0.56 8.26 0.41 3.2e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7481584 0.564 rs432585 chr11:3084903 G/A cg25174290 chr11:3078921 CARS -0.41 -6.03 -0.31 4.36e-9 Calcium levels; LIHC cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg00656387 chr3:40428638 ENTPD3 0.48 7.93 0.39 3.13e-14 Renal cell carcinoma; LIHC cis rs7659604 0.539 rs2063165 chr4:122750005 A/G cg19748678 chr4:122722346 EXOSC9 0.67 11.31 0.52 2.09e-25 Type 2 diabetes; LIHC cis rs2839186 0.843 rs17182671 chr21:47696238 T/C cg12016809 chr21:47604291 C21orf56 0.42 6.07 0.31 3.37e-9 Testicular germ cell tumor; LIHC cis rs1355223 0.934 rs11602669 chr11:34695114 G/A cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.08 -0.31 3.26e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs10197940 0.662 rs4467261 chr2:152281391 G/C cg19508488 chr2:152266495 RIF1 0.58 8.22 0.41 4.26e-15 Lung cancer; LIHC cis rs4906332 1.000 rs4900574 chr14:103879024 G/A cg19000871 chr14:103996768 TRMT61A 0.44 7.75 0.39 1.04e-13 Coronary artery disease; LIHC cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg13607699 chr17:42295918 UBTF 0.62 11.4 0.52 9.78e-26 Total body bone mineral density; LIHC cis rs807029 0.533 rs67813203 chr10:102738551 A/G cg17130504 chr10:102756923 LZTS2 0.56 7.8 0.39 7.35e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg21724239 chr8:58056113 NA 0.58 7.43 0.37 8.85e-13 Developmental language disorder (linguistic errors); LIHC cis rs2836950 0.501 rs62223052 chr21:40708702 A/C cg06238570 chr21:40685208 BRWD1 -0.44 -7.04 -0.36 1.06e-11 Menarche (age at onset); LIHC cis rs10769945 0.679 rs217213 chr11:1979118 C/G cg23202291 chr11:1979235 NA -0.5 -7.41 -0.37 9.87e-13 DNA methylation (variation); LIHC cis rs11676348 0.818 rs6436033 chr2:218983763 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.43 -5.91 -0.3 8.24e-9 Ulcerative colitis; LIHC cis rs74181299 0.750 rs1420185 chr2:65315903 A/G cg05010058 chr2:65284262 CEP68 0.39 6.69 0.34 9.12e-11 Pulse pressure; LIHC cis rs6701037 0.625 rs72719370 chr1:175128536 G/C cg00321850 chr1:175162397 KIAA0040 -0.43 -6.89 -0.35 2.77e-11 Alcohol dependence; LIHC cis rs17253792 0.822 rs17832365 chr14:56153531 C/G cg01858014 chr14:56050164 KTN1 -0.71 -7.29 -0.37 2.16e-12 Putamen volume; LIHC cis rs17376456 0.877 rs34595581 chr5:93369422 G/A cg25358565 chr5:93447407 FAM172A 1.09 10.22 0.48 1.43e-21 Diabetic retinopathy; LIHC cis rs2033711 0.870 rs1465789 chr19:58946056 C/T cg00825309 chr19:58991885 ZNF446 -0.63 -9.64 -0.46 1.32e-19 Uric acid clearance; LIHC cis rs3806843 0.735 rs702394 chr5:140086786 A/G cg16577123 chr5:140027231 NDUFA2;IK -0.4 -5.72 -0.3 2.32e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs13113518 0.812 rs13107810 chr4:56408410 C/A cg15358633 chr12:38710606 ALG10B 0.43 6.19 0.32 1.74e-9 Height; LIHC cis rs7100689 0.577 rs10749550 chr10:82031197 A/G cg01528321 chr10:82214614 TSPAN14 0.86 11.47 0.53 5.7e-26 Post bronchodilator FEV1; LIHC cis rs2070488 0.965 rs2154778 chr3:38553639 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.56 -0.62 1.06e-37 Electrocardiographic conduction measures; LIHC cis rs7572733 0.555 rs6434954 chr2:198929716 T/C cg10820045 chr2:198174542 NA 0.42 6.15 0.32 2.18e-9 Dermatomyositis; LIHC cis rs11098499 0.739 rs6534130 chr4:120131339 A/T cg09307838 chr4:120376055 NA -0.49 -7.45 -0.37 7.74e-13 Corneal astigmatism; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg20102877 chr2:27665638 KRTCAP3 0.41 5.72 0.3 2.34e-8 Total body bone mineral density; LIHC cis rs12479064 0.724 rs62153852 chr2:99934713 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -8.86 -0.43 4.61e-17 Chronic sinus infection; LIHC cis rs4253772 0.720 rs4253778 chr22:46630634 C/G cg24881330 chr22:46731750 TRMU 0.56 6.03 0.31 4.34e-9 LDL cholesterol;Cholesterol, total; LIHC cis rs11792861 0.926 rs72607172 chr9:111876523 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.55 0.42 4.25e-16 Menarche (age at onset); LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg00091569 chr3:40428383 ENTPD3 0.4 6.77 0.34 5.55e-11 Renal cell carcinoma; LIHC cis rs11166927 0.901 rs7827091 chr8:140812044 G/C cg16909799 chr8:140841666 TRAPPC9 0.46 7.37 0.37 1.26e-12 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs10861342 1.000 rs10861357 chr12:105544254 C/T cg23923672 chr12:105501055 KIAA1033 0.65 7.56 0.38 3.84e-13 IgG glycosylation; LIHC cis rs992157 0.835 rs2045434 chr2:219144498 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.12 -0.55 2.19e-28 Colorectal cancer; LIHC cis rs12594515 1.000 rs12595137 chr15:45986105 G/T cg19682013 chr15:45996608 NA 0.41 7.16 0.36 4.83e-12 Waist circumference;Weight; LIHC cis rs7587476 0.784 rs62202001 chr2:215690359 C/G cg04004882 chr2:215674386 BARD1 0.57 7.8 0.39 7.33e-14 Neuroblastoma; LIHC trans rs11098499 0.754 rs9999724 chr4:120239944 C/T cg25214090 chr10:38739885 LOC399744 0.52 8.45 0.42 8.71e-16 Corneal astigmatism; LIHC cis rs508618 1.000 rs508618 chr1:231532312 C/T cg06096015 chr1:231504339 EGLN1 0.45 5.98 0.31 5.51e-9 Red blood cell count; LIHC cis rs896854 0.738 rs481887 chr8:95967838 A/G cg23172400 chr8:95962367 TP53INP1 0.36 7.08 0.36 8.37e-12 Type 2 diabetes; LIHC cis rs7552404 0.655 rs5745336 chr1:76273519 G/A cg10523679 chr1:76189770 ACADM 0.58 7.16 0.36 4.89e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1005277 0.540 rs116205409 chr10:38478970 G/A cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7e-9 Extrinsic epigenetic age acceleration; LIHC cis rs311392 0.903 rs6993362 chr8:55089220 A/G cg11783602 chr8:55087084 NA -0.32 -6.42 -0.33 4.46e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs7575217 0.767 rs6543018 chr2:101730288 A/G cg23907051 chr2:101730305 TBC1D8 0.29 6.6 0.34 1.53e-10 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; LIHC cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg02034447 chr16:89574710 SPG7 0.5 7.56 0.38 3.64e-13 Multiple myeloma (IgH translocation); LIHC cis rs1697139 0.583 rs13186050 chr5:66528139 C/T cg16691251 chr5:66510806 NA 0.45 5.8 0.3 1.53e-8 Breast cancer; LIHC cis rs7552404 0.731 rs1770887 chr1:76401812 A/G cg03433033 chr1:76189801 ACADM -0.52 -6.05 -0.31 3.82e-9 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs748404 0.578 rs2278856 chr15:43631356 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.57 9.22 0.45 3.09e-18 Lung cancer; LIHC cis rs1577917 0.958 rs1591437 chr6:86525305 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.47 -7.47 -0.37 6.81e-13 Response to antipsychotic treatment; LIHC cis rs801193 1.000 rs17566701 chr7:66193183 T/C cg18876405 chr7:65276391 NA 0.4 6.87 0.35 2.97e-11 Aortic root size; LIHC cis rs12477438 0.520 rs4347885 chr2:99804007 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.82 0.51 1.15e-23 Chronic sinus infection; LIHC cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.42 7.25 0.37 2.73e-12 Bipolar disorder; LIHC cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.8 6.29 0.32 9.85e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8180040 0.900 rs10865946 chr3:47425060 T/G cg16586182 chr3:47516702 SCAP -0.57 -10.91 -0.51 5.63e-24 Colorectal cancer; LIHC trans rs1814175 0.817 rs10769641 chr11:49960141 A/G cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC trans rs9914544 0.689 rs11078421 chr17:18804385 A/G cg21372672 chr17:16614065 CCDC144A -0.28 -6.85 -0.35 3.36e-11 Educational attainment (years of education); LIHC cis rs332507 0.750 rs3755680 chr3:124356460 A/G cg05980111 chr3:124395277 KALRN 0.39 6.0 0.31 4.93e-9 Plateletcrit; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26921846 chr21:30671131 BACH1 -0.5 -6.53 -0.33 2.32e-10 Pancreatic cancer; LIHC trans rs11098499 0.691 rs10010355 chr4:120261043 A/G cg25214090 chr10:38739885 LOC399744 0.44 7.32 0.37 1.76e-12 Corneal astigmatism; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg13525026 chr17:18061071 MYO15A 0.43 6.57 0.33 1.89e-10 Bilirubin levels; LIHC cis rs611744 0.967 rs603889 chr8:109224232 C/T cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs6963495 0.606 rs6969426 chr7:105147150 G/A cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg00280220 chr17:61926910 NA -0.43 -6.95 -0.35 1.91e-11 Prudent dietary pattern; LIHC cis rs950169 0.922 rs62028133 chr15:84919375 A/C cg17507749 chr15:85114479 UBE2QP1 0.75 8.92 0.43 2.89e-17 Schizophrenia; LIHC cis rs9467773 1.000 rs6922824 chr6:26553815 C/G cg11502198 chr6:26597334 ABT1 -0.44 -6.46 -0.33 3.51e-10 Intelligence (multi-trait analysis); LIHC cis rs1198430 0.925 rs487859 chr1:23801101 T/C cg13183780 chr1:23809682 ASAP3 -0.56 -8.08 -0.4 1.14e-14 Total cholesterol levels; LIHC cis rs55702914 0.712 rs10931778 chr2:198148922 C/T cg10820045 chr2:198174542 NA -0.39 -5.89 -0.3 9.49e-9 Major depression and alcohol dependence; LIHC cis rs1348850 0.918 rs12622298 chr2:178450651 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.77 11.61 0.53 1.75e-26 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4975709 0.610 rs4975705 chr5:1860359 T/C cg15595755 chr5:1867978 NA 0.41 8.2 0.41 4.95e-15 Cardiovascular disease risk factors; LIHC cis rs6500602 0.727 rs4786515 chr16:4578133 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.49 7.45 0.37 7.88e-13 Schizophrenia; LIHC cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg08280861 chr8:58055591 NA 0.53 6.04 0.31 3.98e-9 Developmental language disorder (linguistic errors); LIHC cis rs1499614 1.000 rs1267817 chr7:66110040 G/T cg18252515 chr7:66147081 NA -1.34 -18.04 -0.7 1.31e-51 Gout; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg07677032 chr17:61819896 STRADA 0.44 6.43 0.33 4.23e-10 Prudent dietary pattern; LIHC cis rs9457247 0.602 rs12208359 chr6:167458455 G/A cg12798992 chr6:167411361 FGFR1OP 0.48 7.03 0.36 1.14e-11 Crohn's disease; LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg06656553 chr16:89960601 TCF25 -0.44 -5.87 -0.3 1.01e-8 Interleukin-17 levels; LIHC cis rs921968 0.565 rs2272188 chr2:219612282 C/T cg02985541 chr2:219472218 PLCD4 0.37 6.31 0.32 8.52e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs11711311 0.824 rs9833810 chr3:113363762 C/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.36 5.99 0.31 5.44e-9 IgG glycosylation; LIHC cis rs9303401 0.659 rs36109237 chr17:56653834 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg07308232 chr7:1071921 C7orf50 -0.42 -6.74 -0.34 6.74e-11 Longevity;Endometriosis; LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.08 -0.31 3.3e-9 Total body bone mineral density; LIHC cis rs4555082 0.874 rs28822720 chr14:105746282 T/C cg13114125 chr14:105738426 BRF1 -0.72 -9.61 -0.46 1.67e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs2153535 0.580 rs6597326 chr6:8482019 A/C cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs35110281 0.743 rs230640 chr21:44914815 A/T cg04455712 chr21:45112962 RRP1B -0.46 -7.61 -0.38 2.68e-13 Mean corpuscular volume; LIHC cis rs875971 0.522 rs781144 chr7:65440344 C/G cg18876405 chr7:65276391 NA 0.54 9.02 0.44 1.38e-17 Aortic root size; LIHC cis rs929354 0.772 rs933344 chr7:157011265 A/T cg16102536 chr7:156981717 UBE3C 0.37 6.19 0.32 1.7e-9 Body mass index; LIHC cis rs2576037 0.526 rs8095373 chr18:44527895 C/T cg19077165 chr18:44547161 KATNAL2 -0.43 -6.62 -0.34 1.38e-10 Personality dimensions; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.77 0.62 1.56e-38 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13622287 chr13:41885293 NAA16 -0.49 -7.15 -0.36 5.14e-12 Pancreatic cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14021555 chr22:43485536 TTLL1 0.45 7.01 0.35 1.26e-11 Cognitive function; LIHC cis rs2841277 0.708 rs28454709 chr14:105405942 G/A cg21017887 chr14:105400489 NA 0.66 12.76 0.57 9.24e-31 Rheumatoid arthritis; LIHC cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg06634786 chr22:41940651 POLR3H -0.81 -8.83 -0.43 5.65e-17 Vitiligo; LIHC cis rs12497850 1.000 rs12497850 chr3:48748989 G/T cg06212747 chr3:49208901 KLHDC8B 0.5 6.48 0.33 3.17e-10 Parkinson's disease; LIHC cis rs9911578 1.000 rs12938772 chr17:56776320 T/C cg12560992 chr17:57184187 TRIM37 0.97 17.39 0.69 5.41e-49 Intelligence (multi-trait analysis); LIHC cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg03517284 chr6:25882590 NA -1.05 -16.17 -0.66 4.53e-44 Uric acid levels; LIHC cis rs7677751 0.767 rs11133315 chr4:55082158 G/A cg17187183 chr4:55093834 PDGFRA 0.62 7.8 0.39 7.46e-14 Corneal astigmatism; LIHC cis rs9560113 0.597 rs1163644 chr13:112241223 C/T cg10483660 chr13:112241077 NA -0.25 -6.51 -0.33 2.68e-10 Menarche (age at onset); LIHC cis rs11583043 1.000 rs17100939 chr1:101443701 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 9.15 0.44 5.43e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs965469 0.948 rs6139079 chr20:3314374 C/T cg25506879 chr20:3388711 C20orf194 0.55 6.3 0.32 8.97e-10 IFN-related cytopenia; LIHC cis rs9929218 0.731 rs72785179 chr16:68767912 C/T cg01231543 chr16:68741748 NA 0.4 6.3 0.32 9.35e-10 Colorectal cancer; LIHC cis rs6598955 0.543 rs79778574 chr1:26538482 A/G cg04990556 chr1:26633338 UBXN11 0.77 11.14 0.52 8.36e-25 Obesity-related traits; LIHC cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.99 9.3 0.45 1.65e-18 Platelet count; LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.99 21.24 0.75 1.92e-64 Prudent dietary pattern; LIHC cis rs2599510 0.811 rs2583713 chr2:32822729 A/G cg02381751 chr2:32503542 YIPF4 0.45 5.88 0.3 9.95e-9 Interleukin-18 levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16203607 chr17:62500946 DDX5 0.45 6.49 0.33 3e-10 Cognitive function; LIHC cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg05368731 chr17:41323189 NBR1 0.72 12.47 0.56 1.08e-29 Menopause (age at onset); LIHC cis rs9814567 0.964 rs12492930 chr3:134222722 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.29 -0.55 5.27e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10857712 1.000 rs10857712 chr10:135225666 T/C cg01444801 chr10:135216882 MTG1 -0.63 -9.38 -0.45 9.41e-19 Systemic lupus erythematosus; LIHC cis rs7572733 0.534 rs1464211 chr2:198798630 G/A cg10820045 chr2:198174542 NA 0.48 7.47 0.37 6.93e-13 Dermatomyositis; LIHC trans rs61931739 0.500 rs9795938 chr12:34587739 C/T cg26384229 chr12:38710491 ALG10B -0.62 -7.72 -0.39 1.25e-13 Morning vs. evening chronotype; LIHC cis rs826838 1.000 rs851934 chr12:39104453 G/T cg26384229 chr12:38710491 ALG10B -0.59 -8.88 -0.43 3.94e-17 Heart rate; LIHC cis rs3091242 0.933 rs7541095 chr1:25761291 T/C cg27572855 chr1:25598939 RHD 0.38 8.09 0.4 1.04e-14 Erythrocyte sedimentation rate; LIHC cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg18252515 chr7:66147081 NA -1.3 -16.95 -0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs1865721 1.000 rs7244787 chr18:73195162 T/C cg26385618 chr18:73139727 C18orf62 -0.3 -7.6 -0.38 2.88e-13 Intelligence; LIHC trans rs1814175 0.817 rs1621090 chr11:49895868 C/A cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs12908161 1.000 rs62021219 chr15:85256159 C/T cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC cis rs8177179 0.967 rs6439436 chr3:133453779 C/T cg18769074 chr3:133464867 TF -0.27 -6.02 -0.31 4.45e-9 Iron status biomarkers (transferrin levels); LIHC cis rs12586317 0.534 rs2273157 chr14:35438836 A/G cg16230307 chr14:35515116 FAM177A1 0.65 11.13 0.52 8.9e-25 Psoriasis; LIHC cis rs921968 0.565 rs7594046 chr2:219624170 A/G cg02985541 chr2:219472218 PLCD4 0.36 6.28 0.32 1.01e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs1506636 0.646 rs805789 chr7:123221920 G/T cg03229431 chr7:123269106 ASB15 -0.44 -8.76 -0.43 9.42e-17 Plateletcrit;Platelet count; LIHC cis rs7756236 0.521 rs11969445 chr6:36625382 C/T cg08179530 chr6:36648295 CDKN1A -0.4 -6.08 -0.31 3.19e-9 QRS duration; LIHC cis rs3540 0.597 rs12708583 chr15:91050271 C/T cg22089800 chr15:90895588 ZNF774 0.49 7.32 0.37 1.81e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs4423214 1.000 rs2002063 chr11:71163476 T/C cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC cis rs7528419 0.927 rs660240 chr1:109817838 T/C cg20569855 chr1:109824440 PSRC1 0.5 6.55 0.33 2.09e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs1878931 0.858 rs3760083 chr16:3450052 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.86 -16.47 -0.67 2.75e-45 Body mass index (adult); LIHC cis rs7551222 0.721 rs1460036 chr1:204527379 A/G cg20240347 chr1:204465584 NA -0.35 -7.51 -0.38 5.04e-13 Schizophrenia; LIHC cis rs1816752 0.805 rs61614647 chr13:25015967 C/T cg02811702 chr13:24901961 NA 0.26 6.63 0.34 1.3100000000000001e-10 Obesity-related traits; LIHC trans rs561341 0.941 rs2470236 chr17:30304940 G/C cg20587970 chr11:113659929 NA -1.22 -10.55 -0.5 1.07e-22 Hip circumference adjusted for BMI; LIHC cis rs2797160 1.000 rs2747719 chr6:126009214 C/T cg05901451 chr6:126070800 HEY2 0.45 7.44 0.37 8.16e-13 Endometrial cancer; LIHC cis rs1348850 0.958 rs10930801 chr2:178459861 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.73 10.62 0.5 5.67e-23 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7666738 0.830 rs6832209 chr4:98994120 A/G cg05340658 chr4:99064831 C4orf37 0.71 12.91 0.57 2.57e-31 Colonoscopy-negative controls vs population controls; LIHC cis rs2274273 1.000 rs1009977 chr14:55603002 T/G cg01864836 chr14:55583639 NA -0.36 -6.65 -0.34 1.18e-10 Protein biomarker; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg22792862 chr14:67827087 EIF2S1;ATP6V1D 0.46 7.17 0.36 4.66e-12 Calcium levels; LIHC cis rs4319547 0.695 rs1973463 chr12:122938003 A/G cg05707623 chr12:122985044 ZCCHC8 -0.58 -7.68 -0.38 1.75e-13 Body mass index; LIHC trans rs3213545 0.700 rs2260399 chr12:121469653 C/T cg01148741 chr2:96811453 DUSP2 -0.39 -6.31 -0.32 8.56e-10 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs2439831 0.681 rs511673 chr15:43618863 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.9 17.06 0.68 1.18e-47 Lung cancer in ever smokers; LIHC cis rs61990749 0.544 rs176979 chr14:78198072 A/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.78 -0.39 8.5e-14 Fibroblast growth factor basic levels; LIHC cis rs751728 1.000 rs4713682 chr6:33757047 G/C cg25922239 chr6:33757077 LEMD2 0.45 7.45 0.37 7.64e-13 Crohn's disease; LIHC cis rs2760061 0.583 rs3094911 chr1:228210179 A/G cg01200585 chr1:228362443 C1orf69 0.48 7.24 0.36 3.02e-12 Diastolic blood pressure; LIHC cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.27 -0.45 2.11e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg00656387 chr3:40428638 ENTPD3 0.43 7.18 0.36 4.35e-12 Renal cell carcinoma; LIHC trans rs11724903 0.935 rs7698943 chr4:183212067 G/A cg16239906 chr20:35724590 RBL1 -0.65 -6.16 -0.32 2.01e-9 Smoking initiation; LIHC cis rs74233809 1.000 rs732998 chr10:104897901 C/T cg03493300 chr10:104813866 CNNM2 -0.45 -6.19 -0.32 1.71e-9 Birth weight; LIHC cis rs6840360 0.615 rs6858483 chr4:152465509 C/T cg22705602 chr4:152727874 NA -0.32 -6.34 -0.32 7.15e-10 Intelligence (multi-trait analysis); LIHC cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.68 -9.87 -0.47 2.27e-20 Lymphocyte counts; LIHC cis rs1153858 0.562 rs8025019 chr15:45735865 C/T cg26924012 chr15:45694286 SPATA5L1 0.79 6.94 0.35 1.94e-11 Homoarginine levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04786791 chr1:218458496 RRP15 0.44 6.44 0.33 3.98e-10 Pancreatic cancer; LIHC cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg06481639 chr22:41940642 POLR3H -0.69 -6.99 -0.35 1.47e-11 Vitiligo; LIHC cis rs1580019 0.587 rs7805311 chr7:32558302 A/G cg07520158 chr7:32535189 LSM5;AVL9 -0.6 -8.93 -0.44 2.57e-17 Cognitive ability; LIHC cis rs7264396 0.561 rs6142474 chr20:34574914 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.47 7.88 0.39 4.29e-14 Total cholesterol levels; LIHC cis rs2576037 0.583 rs541634 chr18:44420271 C/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.93 -0.31 7.49e-9 Personality dimensions; LIHC cis rs7131987 0.903 rs10843373 chr12:29420608 A/T cg21486233 chr12:29375141 FAR2 0.31 6.06 0.31 3.67e-9 QT interval; LIHC cis rs2073300 1.000 rs6106655 chr20:23441982 C/G cg12062639 chr20:23401060 NAPB 0.83 9.96 0.47 1.06e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23543396 chr10:28591431 NA 0.45 6.32 0.32 8.31e-10 Lung function (FEV1/FVC); LIHC trans rs2243480 1.000 rs73142121 chr7:65311206 C/T cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.82e-33 Diabetic kidney disease; LIHC cis rs7953508 0.619 rs11107114 chr12:93972927 G/A cg18151635 chr12:93972918 NA -0.52 -8.91 -0.43 2.99e-17 Pubertal anthropometrics; LIHC cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg17372223 chr3:52568218 NT5DC2 0.36 5.76 0.3 1.83e-8 Bipolar disorder; LIHC cis rs4332037 0.506 rs62442924 chr7:1989976 C/T cg23422044 chr7:1970798 MAD1L1 -0.6 -6.54 -0.33 2.3e-10 Bipolar disorder; LIHC trans rs6058796 1.000 rs6087410 chr20:31258359 C/T cg02600331 chr11:130417168 NA 0.36 7.75 0.39 1.06e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21433820 chr4:4544025 STX18 -0.56 -6.87 -0.35 2.96e-11 Systolic blood pressure; LIHC cis rs3762637 0.943 rs9289196 chr3:122268506 T/C cg24169773 chr3:122142474 KPNA1 -0.39 -8.08 -0.4 1.13e-14 LDL cholesterol levels; LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.79 0.62 1.27e-38 Prudent dietary pattern; LIHC cis rs7617773 1.000 rs11711766 chr3:48193170 G/C cg11946769 chr3:48343235 NME6 -0.66 -8.55 -0.42 4.1e-16 Coronary artery disease; LIHC cis rs7520050 0.966 rs10890352 chr1:46283628 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.98 0.31 5.65e-9 Red blood cell count;Reticulocyte count; LIHC cis rs17608059 0.545 rs736261 chr17:13936404 A/G cg11395062 chr17:14139857 CDRT15 0.59 11.04 0.51 1.9e-24 Temperament; LIHC cis rs1005277 0.540 rs2145487 chr10:38010077 A/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.61 -0.46 1.65e-19 Extrinsic epigenetic age acceleration; LIHC cis rs10751667 0.666 rs6597967 chr11:950583 G/T ch.11.42038R chr11:967971 AP2A2 0.54 9.74 0.47 5.96e-20 Alzheimer's disease (late onset); LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg11965913 chr1:205819406 PM20D1 -0.62 -9.05 -0.44 1.08e-17 Menarche (age at onset); LIHC cis rs5769765 0.874 rs4624 chr22:50281917 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.2 0.45 3.71e-18 Schizophrenia; LIHC cis rs35110281 0.712 rs8133523 chr21:45062403 A/G cg04455712 chr21:45112962 RRP1B 0.46 7.86 0.39 5.1e-14 Mean corpuscular volume; LIHC cis rs7296418 0.961 rs949143 chr12:123595163 G/A cg05973401 chr12:123451056 ABCB9 0.49 7.57 0.38 3.49e-13 Platelet count; LIHC cis rs739401 1.000 rs739401 chr11:3036324 C/T cg25174290 chr11:3078921 CARS -0.39 -5.98 -0.31 5.78e-9 Longevity; LIHC cis rs6674176 0.660 rs3791112 chr1:44379248 T/G cg12908607 chr1:44402522 ARTN -0.5 -8.27 -0.41 2.95e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6882046 0.513 rs679232 chr5:88054763 A/C cg22951263 chr5:87985283 NA 0.39 6.75 0.34 6.46e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC trans rs867371 1.000 rs7173339 chr15:82467594 A/G cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.1 -0.36 7.13e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.31 0.45 1.56e-18 Electroencephalogram traits; LIHC cis rs9814567 0.896 rs58491661 chr3:134355189 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.58 9.48 0.46 4.38e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.95 -0.31 6.51e-9 Total body bone mineral density; LIHC cis rs4718428 0.705 rs68168107 chr7:66255238 G/A cg12165864 chr7:66369176 NA -0.47 -6.76 -0.34 5.8200000000000003e-11 Corneal structure; LIHC cis rs753955 0.592 rs1324972 chr13:24348159 C/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.32 5.74 0.3 2.13e-8 Lung cancer; LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.539 rs12999417 chr2:99865548 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -20.1 -0.74 6.85e-60 Chronic sinus infection; LIHC cis rs597539 0.654 rs619727 chr11:68627535 A/G cg04772025 chr11:68637568 NA 0.49 6.64 0.34 1.23e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9457247 1.000 rs9457247 chr6:167392174 C/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg15586393 chr4:1244086 CTBP1;C4orf42 -0.43 -6.16 -0.32 2.03e-9 Longevity; LIHC cis rs2404602 0.503 rs284909 chr15:76736628 C/T cg03037974 chr15:76606532 NA 0.66 12.16 0.55 1.55e-28 Blood metabolite levels; LIHC trans rs2727020 0.658 rs4980442 chr11:49445016 G/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.49 -0.73 1.89e-57 Coronary artery disease; LIHC cis rs11583043 1.000 rs35445887 chr1:101523639 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 8.54 0.42 4.47e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4665809 1.000 rs1550381 chr2:26266946 A/G cg04944784 chr2:26401820 FAM59B -0.71 -8.92 -0.43 2.85e-17 Gut microbiome composition (summer); LIHC cis rs9457247 0.756 rs1811123 chr6:167403443 T/C cg12798992 chr6:167411361 FGFR1OP 0.6 10.0 0.48 7.75e-21 Crohn's disease; LIHC cis rs738321 0.756 rs4821740 chr22:38514423 C/G cg25457927 chr22:38595422 NA -0.28 -6.38 -0.33 5.61e-10 Breast cancer; LIHC cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg06212747 chr3:49208901 KLHDC8B 0.64 8.74 0.43 1.04e-16 Menarche (age at onset); LIHC cis rs4689592 0.503 rs2292461 chr4:7058473 C/T cg19539972 chr4:7069911 GRPEL1 0.61 8.83 0.43 5.48e-17 Monocyte percentage of white cells; LIHC cis rs950169 0.922 rs12906983 chr15:84931022 G/A cg03959625 chr15:84868606 LOC388152 0.49 6.98 0.35 1.56e-11 Schizophrenia; LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.69 -0.34 9.38e-11 Total body bone mineral density; LIHC cis rs2279817 1.000 rs2279816 chr1:18021867 T/C cg21791023 chr1:18019539 ARHGEF10L 0.64 8.88 0.43 3.97e-17 Neuroticism; LIHC cis rs992157 0.560 rs12987130 chr2:219104990 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.75 -12.3 -0.55 5.02e-29 Colorectal cancer; LIHC cis rs5769707 0.904 rs7288869 chr22:50015327 C/T cg01652190 chr22:50026171 C22orf34 -0.31 -7.12 -0.36 6.27e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2997447 0.595 rs3008425 chr1:26385660 T/C cg19633962 chr1:26362018 EXTL1 -0.61 -7.58 -0.38 3.36e-13 QRS complex (12-leadsum); LIHC cis rs7520050 0.581 rs3855959 chr1:46633874 C/T cg06787764 chr1:46668870 C1orf190;POMGNT1 0.49 7.26 0.37 2.67e-12 Red blood cell count;Reticulocyte count; LIHC cis rs2257205 0.667 rs1018051 chr17:56909926 A/G cg05425664 chr17:57184151 TRIM37 -0.54 -6.02 -0.31 4.41e-9 Pancreatic cancer; LIHC cis rs769267 0.965 rs2269873 chr19:19392401 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.01 0.31 4.89e-9 Tonsillectomy; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs240764 0.853 rs12660725 chr6:100978570 C/T cg09795085 chr6:101329169 ASCC3 -0.43 -5.78 -0.3 1.65e-8 Neuroticism; LIHC cis rs6547741 0.935 rs4665384 chr2:27848397 A/G cg27432699 chr2:27873401 GPN1 0.78 12.75 0.57 1.01e-30 Oral cavity cancer; LIHC cis rs798554 0.523 rs1182197 chr7:2863289 A/C cg19717773 chr7:2847554 GNA12 -0.41 -6.99 -0.35 1.48e-11 Height; LIHC cis rs6542838 0.609 rs13028500 chr2:99528296 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.43 -7.15 -0.36 5.26e-12 Fear of minor pain; LIHC cis rs72627123 0.867 rs17094448 chr14:74440119 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.48 0.42 6.78e-16 Morning vs. evening chronotype; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg22903471 chr2:27725779 GCKR -0.5 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs1707322 1.000 rs7539800 chr1:46262129 C/G cg06784218 chr1:46089804 CCDC17 -0.37 -6.44 -0.33 4.15e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11190604 1.000 rs7099913 chr10:102314777 T/C cg07080220 chr10:102295463 HIF1AN 0.53 7.26 0.37 2.67e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7044106 0.791 rs10985000 chr9:123484115 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.78 0.39 8.7e-14 Hip circumference adjusted for BMI; LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg13126279 chr21:47581558 C21orf56 0.44 7.22 0.36 3.46e-12 Testicular germ cell tumor; LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg11494091 chr17:61959527 GH2 0.44 7.9 0.39 3.86e-14 Prudent dietary pattern; LIHC trans rs66887589 0.934 rs41464847 chr4:120532401 A/G cg25214090 chr10:38739885 LOC399744 -0.41 -6.76 -0.34 6.04e-11 Diastolic blood pressure; LIHC trans rs10411161 0.702 rs16983196 chr19:52384779 C/A cg22319618 chr22:45562946 NUP50 -0.59 -8.12 -0.4 8.66e-15 Breast cancer; LIHC cis rs1577917 0.771 rs2842602 chr6:86331887 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -12.21 -0.55 1.02e-28 Response to antipsychotic treatment; LIHC cis rs10751667 0.961 rs6597953 chr11:991099 G/A cg10932868 chr11:921992 NA 0.34 6.32 0.32 8.33e-10 Alzheimer's disease (late onset); LIHC cis rs2281845 0.965 rs3738263 chr1:201083506 A/G cg24849736 chr1:201084428 NA -0.41 -8.23 -0.41 4.01e-15 Permanent tooth development; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg27266822 chr1:16073415 TMEM82 0.48 6.21 0.32 1.55e-9 Hepatitis; LIHC cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg09904177 chr6:26538194 HMGN4 0.57 11.21 0.52 4.9e-25 Intelligence (multi-trait analysis); LIHC cis rs8077889 0.917 rs4793037 chr17:41914826 C/T cg26893861 chr17:41843967 DUSP3 1.01 11.25 0.52 3.38e-25 Triglycerides; LIHC cis rs847649 0.924 rs6960428 chr7:102589706 C/G cg18108683 chr7:102477205 FBXL13 0.49 7.5 0.38 5.38e-13 Morning vs. evening chronotype; LIHC cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg17554472 chr22:41940697 POLR3H 0.55 6.13 0.31 2.49e-9 Vitiligo; LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg06951627 chr6:26196580 NA 0.55 6.43 0.33 4.39e-10 Gout;Renal underexcretion gout; LIHC cis rs1348850 0.789 rs13027959 chr2:178275887 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.41 0.59 2.92e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg03264133 chr6:25882463 NA -0.43 -6.39 -0.33 5.59e-10 Height; LIHC cis rs34779708 0.931 rs67976880 chr10:35372261 G/C cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2710642 0.611 rs6706506 chr2:62861824 T/C cg17519650 chr2:63277830 OTX1 0.47 6.88 0.35 2.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs8103278 1.000 rs7256192 chr19:46338492 G/A cg02376097 chr19:46275166 DMPK -0.45 -6.84 -0.35 3.64e-11 Coronary artery disease; LIHC cis rs4148883 0.629 rs10009145 chr4:100047929 G/A cg12011299 chr4:100065546 ADH4 0.36 7.2 0.36 3.81e-12 Alcohol dependence; LIHC cis rs7208859 0.623 rs56325146 chr17:29151024 T/C cg14067834 chr17:29058358 SUZ12P 0.69 6.76 0.34 6.04e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs60752752 0.852 rs12044231 chr1:153370876 G/A cg14901121 chr8:98817630 LAPTM4B -0.44 -7.35 -0.37 1.44e-12 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs7131987 0.650 rs4331146 chr12:29440083 G/T cg05697976 chr12:29376483 FAR2 0.31 6.29 0.32 9.63e-10 QT interval; LIHC cis rs61041384 0.661 rs4148857 chr12:123539955 T/C cg25930673 chr12:123319894 HIP1R 0.64 5.83 0.3 1.31e-8 Schizophrenia; LIHC cis rs7945705 0.840 rs10840136 chr11:8885024 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -9.26 -0.45 2.36e-18 Hemoglobin concentration; LIHC cis rs6499255 1.000 rs6499253 chr16:69802672 C/T cg15192750 chr16:69999425 NA 0.45 6.75 0.34 6.39e-11 IgE levels; LIHC cis rs1005277 0.579 rs2474599 chr10:38438939 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs9300255 0.596 rs1568427 chr12:123738678 A/G cg00376283 chr12:123451042 ABCB9 0.67 10.06 0.48 4.95e-21 Neutrophil percentage of white cells; LIHC cis rs9325144 0.505 rs7138977 chr12:38642109 G/A cg26384229 chr12:38710491 ALG10B 0.46 7.3 0.37 1.97e-12 Morning vs. evening chronotype; LIHC trans rs7618501 0.571 rs2240329 chr3:50107512 G/A cg21659725 chr3:3221576 CRBN -0.67 -10.89 -0.51 6.46e-24 Intelligence (multi-trait analysis); LIHC cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg24675658 chr1:53192096 ZYG11B 0.83 13.88 0.6 4.75e-35 Monocyte count; LIHC cis rs7772486 0.686 rs9403739 chr6:146015357 A/G cg23711669 chr6:146136114 FBXO30 -0.66 -10.87 -0.51 8.03e-24 Lobe attachment (rater-scored or self-reported); LIHC trans rs2727020 0.688 rs4929894 chr11:49196333 G/C cg15704280 chr7:45808275 SEPT13 -0.88 -15.89 -0.65 5.52e-43 Coronary artery disease; LIHC cis rs4843747 0.636 rs11864872 chr16:88105966 A/G cg06050784 chr16:88016603 BANP 0.35 6.44 0.33 4.11e-10 Menopause (age at onset); LIHC cis rs6963495 0.745 rs56239334 chr7:105165351 G/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs4819052 0.724 rs1304487 chr21:46657283 C/G cg11663144 chr21:46675770 NA 0.31 5.89 0.3 9.44e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs875971 0.660 rs10281080 chr7:66042441 T/C cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.96 9.41 0.45 7.68e-19 Platelet count; LIHC cis rs11148252 0.846 rs4886077 chr13:52998697 G/T cg00495681 chr13:53174319 NA 0.38 6.25 0.32 1.19e-9 Lewy body disease; LIHC trans rs17770015 0.759 rs10749129 chr10:115187221 T/G cg12758090 chr15:80543408 NA -0.43 -6.17 -0.32 1.9e-9 Migraine without aura; LIHC cis rs5769707 0.681 rs135879 chr22:50018651 C/T cg01652190 chr22:50026171 C22orf34 -0.34 -7.64 -0.38 2.2e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7249142 0.526 rs7256811 chr19:19283551 A/G cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.35 -5.91 -0.3 8.13e-9 IgG glycosylation; LIHC cis rs1707322 1.000 rs11211236 chr1:46443767 C/A cg03146154 chr1:46216737 IPP 0.48 7.86 0.39 5.02e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7772486 0.754 rs697053 chr6:145989807 T/C cg13319975 chr6:146136371 FBXO30 0.41 6.75 0.34 6.29e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs709400 0.930 rs28513222 chr14:104028069 A/T cg26031613 chr14:104095156 KLC1 1.14 14.34 0.61 7.54e-37 Body mass index; LIHC cis rs9549328 0.837 rs9549618 chr13:113628648 G/A cg18289306 chr13:113640169 MCF2L 0.41 6.38 0.33 5.75e-10 Systolic blood pressure; LIHC cis rs12477438 0.501 rs17759607 chr2:99737005 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 9.9 0.47 1.76e-20 Chronic sinus infection; LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.87 0.57 3.48e-31 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg08280861 chr8:58055591 NA 0.49 6.68 0.34 9.83e-11 Developmental language disorder (linguistic errors); LIHC trans rs2749592 0.505 rs7915670 chr10:37870212 T/C cg17830980 chr10:43048298 ZNF37B 0.42 7.91 0.39 3.5e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg11070056 chr1:107600091 PRMT6 0.7 12.08 0.55 3.17e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs8177253 0.896 rs34252038 chr3:133490621 G/T cg12373951 chr3:133503437 NA 0.7 12.47 0.56 1.15e-29 Iron status biomarkers; LIHC cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg11890956 chr21:40555474 PSMG1 -0.5 -8.37 -0.41 1.48e-15 Menarche (age at onset); LIHC cis rs10426930 0.607 rs2613755 chr19:5059941 A/G cg18473234 chr19:5097819 KDM4B -0.55 -6.64 -0.34 1.21e-10 Monocyte percentage of white cells; LIHC cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg02475777 chr4:1388615 CRIPAK -0.53 -8.2 -0.41 4.84e-15 Longevity; LIHC cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg18230493 chr5:56204884 C5orf35 -0.44 -6.12 -0.31 2.54e-9 Initial pursuit acceleration; LIHC cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg10802521 chr3:52805072 NEK4 -0.43 -7.0 -0.35 1.4e-11 Bipolar disorder; LIHC cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg09904177 chr6:26538194 HMGN4 0.57 11.56 0.53 2.66e-26 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs6503727 chr17:41312859 C/T cg25072359 chr17:41440525 NA 0.4 6.32 0.32 8.36e-10 Menopause (age at onset); LIHC cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg23221052 chr5:179740743 GFPT2 0.44 6.18 0.32 1.87e-9 Height; LIHC cis rs6964587 1.000 rs60147309 chr7:91736098 C/G cg17063962 chr7:91808500 NA 1.01 19.34 0.72 8.03e-57 Breast cancer; LIHC cis rs3806843 0.735 rs2530241 chr5:140054485 C/T cg19875535 chr5:140030758 IK -0.41 -6.7 -0.34 8.52e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs7539409 0.833 rs2057083 chr1:84269942 T/G cg10977910 chr1:84465055 TTLL7 0.75 6.23 0.32 1.34e-9 Alzheimer's disease; LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs916888 0.821 rs199499 chr17:44865498 C/T cg01570182 chr17:44337453 NA 0.95 7.81 0.39 6.91e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9325144 0.560 rs2387924 chr12:38662883 A/G cg26384229 chr12:38710491 ALG10B -0.49 -7.42 -0.37 9.38e-13 Morning vs. evening chronotype; LIHC cis rs7589728 0.563 rs4972044 chr2:88466196 T/C cg04511125 chr2:88470314 THNSL2 0.97 9.91 0.47 1.56e-20 Plasma clusterin levels; LIHC cis rs9583531 0.629 rs7991766 chr13:111380684 A/G cg24331049 chr13:111365604 ING1 0.77 12.39 0.56 2.16e-29 Coronary artery disease; LIHC trans rs9914544 0.545 rs57035178 chr17:18797767 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.53 -0.33 2.44e-10 Educational attainment (years of education); LIHC cis rs6542838 0.704 rs13011428 chr2:99528305 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.53 -0.33 2.42e-10 Fear of minor pain; LIHC cis rs4919694 1.000 rs76255497 chr10:104651955 T/C cg04362960 chr10:104952993 NT5C2 0.78 7.89 0.39 4.2e-14 Arsenic metabolism; LIHC cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.36 0.45 1.12e-18 Platelet count; LIHC cis rs2075371 0.611 rs13235296 chr7:134019192 A/G cg20476274 chr7:133979776 SLC35B4 -0.48 -6.53 -0.33 2.36e-10 Mean platelet volume; LIHC cis rs1395 0.744 rs1122227 chr2:27544285 C/T cg22903471 chr2:27725779 GCKR -0.43 -6.29 -0.32 9.94e-10 Blood metabolite levels; LIHC cis rs56104184 0.830 rs17206679 chr19:49342237 C/G cg15549821 chr19:49342101 PLEKHA4 -1.22 -10.23 -0.48 1.34e-21 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs1949733 1.000 rs2688233 chr4:8491885 T/C cg11789530 chr4:8429930 ACOX3 0.82 12.05 0.55 4.24e-28 Response to antineoplastic agents; LIHC cis rs7552404 0.824 rs1251079 chr1:76189445 C/T cg03433033 chr1:76189801 ACADM 0.79 18.55 0.71 1.19e-53 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11055008 0.620 rs10845608 chr12:12836088 C/T cg04607235 chr12:12878440 APOLD1 0.49 7.47 0.37 6.9e-13 Pulse pressure; LIHC cis rs72781680 0.716 rs7564732 chr2:24034178 C/T cg08917208 chr2:24149416 ATAD2B 0.61 6.17 0.32 1.97e-9 Lymphocyte counts; LIHC cis rs722599 0.715 rs8008785 chr14:75307600 G/A cg11812906 chr14:75593930 NEK9 -0.41 -6.23 -0.32 1.35e-9 IgG glycosylation; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg09367891 chr1:107599246 PRMT6 0.72 11.98 0.54 7.3e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3767633 0.925 rs4579731 chr1:161766859 G/A cg09175582 chr1:161736000 ATF6 0.57 5.88 0.3 9.8e-9 IgG glycosylation; LIHC cis rs7520050 0.931 rs35743647 chr1:46407252 T/C cg03146154 chr1:46216737 IPP -0.38 -6.36 -0.33 6.47e-10 Red blood cell count;Reticulocyte count; LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.51 7.24 0.36 2.99e-12 Height; LIHC cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg11764359 chr7:65958608 NA 0.59 6.05 0.31 3.74e-9 Diabetic kidney disease; LIHC cis rs1865760 0.532 rs1061482 chr6:26086699 G/T cg18357526 chr6:26021779 HIST1H4A 0.45 6.53 0.33 2.33e-10 Height; LIHC cis rs11031096 0.711 rs17283923 chr11:4173841 C/T cg18678763 chr11:4115507 RRM1 -0.41 -5.96 -0.31 6.12e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs9814567 1.000 rs6763088 chr3:134254989 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10078 0.571 rs2721014 chr5:463539 G/A cg26072250 chr5:443457 EXOC3;C5orf55 0.76 10.21 0.48 1.55e-21 Fat distribution (HIV); LIHC cis rs2303759 0.709 rs10422677 chr19:49824290 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.53 7.89 0.39 4.02e-14 Multiple sclerosis; LIHC cis rs2991971 0.967 rs2275276 chr1:45973928 C/T cg24296786 chr1:45957014 TESK2 0.59 9.4 0.45 7.86e-19 High light scatter reticulocyte count; LIHC trans rs1814175 0.645 rs2140602 chr11:50022800 G/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs1552244 0.554 rs3732964 chr3:10048839 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC trans rs3758911 0.796 rs10890719 chr11:107204083 A/T cg21068293 chr15:74496576 STRA6 0.26 6.25 0.32 1.21e-9 Coronary artery disease; LIHC cis rs7224737 1.000 rs2014521 chr17:40283413 C/G cg00647820 chr17:40259828 DHX58 -0.27 -5.75 -0.3 1.96e-8 Fibrinogen levels; LIHC cis rs17739167 0.550 rs6493013 chr15:42224824 T/C cg20935245 chr15:42234343 EHD4 0.4 7.28 0.37 2.29e-12 Monocyte count; LIHC cis rs6665290 0.904 rs6684821 chr1:227190233 G/A cg10327440 chr1:227177885 CDC42BPA -1.18 -25.74 -0.81 4.9e-82 Myeloid white cell count; LIHC cis rs11588062 1.000 rs11588062 chr1:46779764 C/T cg15696662 chr1:46669221 C1orf190;POMGNT1 0.5 7.77 0.39 9.41e-14 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs798554 0.757 rs2533882 chr7:2846894 G/T cg04166393 chr7:2884313 GNA12 0.48 6.49 0.33 2.96e-10 Height; LIHC cis rs11229555 0.609 rs12273635 chr11:58186327 T/C cg15696309 chr11:58395628 NA -0.65 -7.7 -0.38 1.48e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9814567 1.000 rs2370641 chr3:134222161 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.29 -0.55 5.27e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1814175 0.715 rs7479622 chr11:49673340 T/G cg03929089 chr4:120376271 NA -0.89 -17.59 -0.69 8.81e-50 Height; LIHC cis rs918629 0.798 rs57595413 chr5:95277776 C/T cg10483112 chr5:95245456 ELL2 -0.35 -6.02 -0.31 4.47e-9 IgG glycosylation; LIHC cis rs8083850 0.635 rs12954274 chr18:50865874 C/T cg24270629 chr18:50823537 DCC 0.53 8.01 0.4 1.83e-14 Intelligence (multi-trait analysis); LIHC cis rs10779751 0.734 rs1034528 chr1:11249132 G/C cg08854313 chr1:11322531 MTOR -0.79 -12.07 -0.55 3.48e-28 Body mass index; LIHC cis rs74544699 1.000 rs353034 chr4:74773643 G/A cg02530824 chr4:74847766 PF4 0.62 6.47 0.33 3.42e-10 Growth-regulated protein alpha levels; LIHC cis rs801193 1.000 rs7788576 chr7:66148302 G/A cg11764359 chr7:65958608 NA -0.71 -10.56 -0.5 9.29e-23 Aortic root size; LIHC cis rs6430585 0.583 rs58116536 chr2:136585323 C/T cg07169764 chr2:136633963 MCM6 1.34 21.19 0.75 2.97e-64 Corneal structure; LIHC cis rs3762637 0.941 rs60222267 chr3:122179632 G/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs11583043 1.000 rs6675353 chr1:101459625 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 9.33 0.45 1.38e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs780096 0.587 rs1049817 chr2:27550967 A/G cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.86 -0.3 1.06e-8 Total body bone mineral density; LIHC cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg05368731 chr17:41323189 NBR1 0.71 11.84 0.54 2.52e-27 Menopause (age at onset); LIHC cis rs10744422 1.000 rs2343108 chr12:123331301 C/T cg07706471 chr12:123319906 HIP1R -0.62 -8.14 -0.4 7.43e-15 Schizophrenia; LIHC cis rs55665837 1.000 rs10766182 chr11:14499536 A/G cg19336497 chr11:14380999 RRAS2 -0.45 -8.08 -0.4 1.16e-14 Vitamin D levels; LIHC cis rs422249 0.512 rs174577 chr11:61604814 A/C cg27386326 chr11:61587980 NA -0.69 -14.99 -0.63 2.18e-39 Trans fatty acid levels; LIHC cis rs12451471 0.620 rs11150846 chr17:78098520 C/T cg06718696 chr17:78121285 EIF4A3 0.95 11.29 0.52 2.43e-25 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs6456156 0.792 rs10946212 chr6:167515947 C/G cg07741184 chr6:167504864 NA 0.26 6.51 0.33 2.73e-10 Primary biliary cholangitis; LIHC cis rs1005277 0.579 rs1780146 chr10:38517874 C/A cg25427524 chr10:38739819 LOC399744 -0.72 -13.99 -0.6 1.75e-35 Extrinsic epigenetic age acceleration; LIHC cis rs7131987 0.683 rs7954278 chr12:29459290 G/A cg14222432 chr12:29376421 FAR2 0.35 6.75 0.34 6.28e-11 QT interval; LIHC cis rs7116495 0.588 rs547208 chr11:71779668 A/G cg26138937 chr11:71823887 C11orf51 -0.8 -7.93 -0.39 3.22e-14 Severe influenza A (H1N1) infection; LIHC cis rs523522 0.962 rs10849757 chr12:120964014 G/A cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg08219700 chr8:58056026 NA 0.5 6.22 0.32 1.49e-9 Developmental language disorder (linguistic errors); LIHC cis rs8014204 1.000 rs8014204 chr14:75322794 A/G cg08847533 chr14:75593920 NEK9 0.35 5.89 0.3 9.33e-9 Caffeine consumption; LIHC cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg15691649 chr6:25882328 NA -0.7 -10.54 -0.5 1.08e-22 Blood metabolite levels; LIHC cis rs11098499 0.580 rs12509234 chr4:120319434 T/C cg09307838 chr4:120376055 NA 0.76 11.85 0.54 2.28e-27 Corneal astigmatism; LIHC cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg11764359 chr7:65958608 NA 0.55 5.87 0.3 1.04e-8 Diabetic kidney disease; LIHC cis rs3806843 1.000 rs3756342 chr5:140165624 G/A cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.53e-10 Depressive symptoms (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25019777 chr4:53525403 USP46 -0.56 -6.08 -0.31 3.28e-9 Systolic blood pressure; LIHC trans rs9926296 0.618 rs8058179 chr16:89846987 C/T cg25047469 chr15:90198526 KIF7 -0.49 -6.14 -0.32 2.24e-9 Vitiligo; LIHC cis rs4742903 1.000 rs3780535 chr9:106894211 A/C cg14250997 chr9:106856677 SMC2 0.42 7.44 0.37 8.21e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs34779708 0.931 rs12240347 chr10:35359475 A/G cg03585969 chr10:35415529 CREM 0.79 11.84 0.54 2.47e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4240897 0.935 rs1474868 chr1:12044164 A/G cg13216073 chr1:12042593 MFN2 -0.49 -8.0 -0.4 1.88e-14 Tuberculosis; LIHC cis rs875971 0.522 rs1880556 chr7:65432544 T/C cg26939375 chr7:64535504 NA 0.46 6.93 0.35 2.09e-11 Aortic root size; LIHC cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg02290350 chr8:58132656 NA 0.42 8.88 0.43 3.83e-17 Developmental language disorder (linguistic errors); LIHC cis rs6840360 1.000 rs9998462 chr4:152646548 T/A cg22705602 chr4:152727874 NA -0.35 -7.37 -0.37 1.33e-12 Intelligence (multi-trait analysis); LIHC cis rs9322817 0.691 rs1933804 chr6:105341969 G/C cg02098413 chr6:105308735 HACE1 0.39 7.49 0.38 6.03e-13 Thyroid stimulating hormone; LIHC cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg08219700 chr8:58056026 NA 0.5 6.49 0.33 2.98e-10 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.616 rs10839341 chr11:49742615 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.81 0.35 4.37e-11 Height; LIHC cis rs4819052 0.851 rs2838842 chr21:46669217 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.79 0.39 8.22e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg01765077 chr12:122356316 WDR66 -0.44 -6.69 -0.34 9.37e-11 Mean corpuscular volume; LIHC cis rs7264396 0.561 rs6058387 chr20:34568092 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -8.03 -0.4 1.59e-14 Total cholesterol levels; LIHC cis rs4319547 0.585 rs10846792 chr12:122882374 T/C cg23029597 chr12:123009494 RSRC2 -0.51 -7.18 -0.36 4.37e-12 Body mass index; LIHC cis rs4725617 0.686 rs4283960 chr7:143103380 C/T cg10228500 chr7:143105595 EPHA1 -0.48 -5.94 -0.31 7.03e-9 Blood protein levels; LIHC cis rs1023500 0.573 rs13057094 chr22:42470317 T/C cg05082376 chr22:42548792 NA -0.4 -5.9 -0.3 8.74e-9 Schizophrenia; LIHC cis rs2439831 1.000 rs2467736 chr15:43784917 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.64 9.01 0.44 1.47e-17 Lung cancer in ever smokers; LIHC cis rs1165668 1.000 rs1165669 chr12:104318172 C/T cg21863207 chr12:104234989 NT5DC3 -0.38 -6.01 -0.31 4.88e-9 Coronary heart disease (SNP X SNP interaction); LIHC cis rs7959452 0.535 rs11615712 chr12:69619736 A/T cg14784868 chr12:69753453 YEATS4 -0.73 -13.28 -0.58 9.35e-33 Blood protein levels; LIHC cis rs16958440 1.000 rs61316646 chr18:44610670 G/C cg17192377 chr18:44677553 HDHD2 0.6 6.65 0.34 1.14e-10 Sitting height ratio; LIHC cis rs8017423 0.935 rs3742667 chr14:90767856 T/C cg04374321 chr14:90722782 PSMC1 -0.77 -14.72 -0.62 2.58e-38 Mortality in heart failure; LIHC cis rs2933343 0.649 rs1683786 chr3:128626952 T/C cg25356066 chr3:128598488 ACAD9 0.53 7.39 0.37 1.14e-12 IgG glycosylation; LIHC cis rs77633900 0.772 rs157769 chr15:76834397 G/A cg21673338 chr15:77095150 SCAPER -0.53 -5.92 -0.3 7.98e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs5753618 0.509 rs5997902 chr22:31583007 A/G cg22777020 chr22:31556080 RNF185 -0.55 -6.21 -0.32 1.56e-9 Colorectal cancer; LIHC cis rs763121 0.853 rs1043441 chr22:39130964 C/T cg06022373 chr22:39101656 GTPBP1 0.72 13.97 0.6 2.13e-35 Menopause (age at onset); LIHC cis rs12477438 0.798 rs1993230 chr2:99686079 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -16.01 -0.65 1.99e-43 Chronic sinus infection; LIHC cis rs7937682 0.632 rs7112886 chr11:111743232 T/C cg09085632 chr11:111637200 PPP2R1B 0.93 13.32 0.58 6.82e-33 Primary sclerosing cholangitis; LIHC cis rs2637266 1.000 rs7073355 chr10:78354419 G/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs6879260 1.000 rs7706951 chr5:179733407 C/T cg23221052 chr5:179740743 GFPT2 -0.43 -6.02 -0.31 4.44e-9 Height; LIHC cis rs801193 1.000 rs4717310 chr7:66161007 C/T cg00343986 chr7:65444356 GUSB 0.4 5.92 0.3 8.02e-9 Aortic root size; LIHC cis rs8072100 0.967 rs3760370 chr17:45695832 C/T cg08085267 chr17:45401833 C17orf57 0.41 6.18 0.32 1.83e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7772486 0.846 rs9373482 chr6:146363123 A/C cg05347473 chr6:146136440 FBXO30 0.38 6.13 0.31 2.4e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1670533 1.000 rs6827357 chr4:1059202 A/C cg27284194 chr4:1044797 NA 0.61 8.81 0.43 6.4e-17 Recombination rate (females); LIHC cis rs17685 0.753 rs10264760 chr7:75749694 A/G cg04610667 chr7:75704037 NA -0.34 -6.09 -0.31 3.04e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs916888 0.821 rs415430 chr17:44859144 C/T cg13957321 chr17:43675089 NA -0.48 -7.72 -0.39 1.29e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs35110281 0.693 rs2838345 chr21:45092715 C/T cg04455712 chr21:45112962 RRP1B 0.54 9.54 0.46 2.74e-19 Mean corpuscular volume; LIHC cis rs908922 0.584 rs71626721 chr1:152532745 A/G cg20991723 chr1:152506922 NA 0.55 9.13 0.44 6.09e-18 Hair morphology; LIHC trans rs9951602 0.512 rs12455591 chr18:76656028 A/G cg02800362 chr5:177631904 HNRNPAB 0.65 10.17 0.48 2.07e-21 Obesity-related traits; LIHC cis rs2016586 0.894 rs2413367 chr22:36101861 A/T cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 8.08e-10 Body mass index; LIHC cis rs13392177 0.647 rs6718220 chr2:219066518 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.55 -7.82 -0.39 6.52e-14 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs7617773 0.780 rs4479622 chr3:48338173 C/T cg11946769 chr3:48343235 NME6 0.92 11.62 0.53 1.58e-26 Coronary artery disease; LIHC cis rs2066819 1.000 rs2291361 chr12:56717805 G/A cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs2070488 0.775 rs6780349 chr3:38555178 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.67 -11.12 -0.52 9.65e-25 Electrocardiographic conduction measures; LIHC cis rs9325144 0.560 rs7314632 chr12:38636979 C/T cg26384229 chr12:38710491 ALG10B -0.48 -7.51 -0.38 5.26e-13 Morning vs. evening chronotype; LIHC cis rs9858542 0.537 rs4410472 chr3:49329090 A/T cg07636037 chr3:49044803 WDR6 -0.53 -5.92 -0.3 7.92e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs11098699 1.000 rs11941747 chr4:124208968 A/G cg09941581 chr4:124220074 SPATA5 0.32 6.04 0.31 4e-9 Mosquito bite size; LIHC cis rs8005677 1.000 rs8016061 chr14:23375809 A/G cg07971674 chr14:23388846 RBM23 -0.41 -5.89 -0.3 9.2e-9 Cognitive ability (multi-trait analysis); LIHC cis rs1707322 0.721 rs10890344 chr1:46166090 C/T cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2191566 0.664 rs62115477 chr19:44543027 T/G cg20607764 chr19:44506953 ZNF230 -0.37 -6.22 -0.32 1.43e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg26354017 chr1:205819088 PM20D1 0.77 11.25 0.52 3.28e-25 Menarche (age at onset); LIHC cis rs4423214 0.798 rs1894100 chr11:71130343 G/T cg05163923 chr11:71159392 DHCR7 -0.67 -8.88 -0.43 3.89e-17 Vitamin D levels; LIHC cis rs11690935 0.550 rs62183801 chr2:172867475 G/A cg13550731 chr2:172543902 DYNC1I2 0.44 6.83 0.35 4.01e-11 Schizophrenia; LIHC cis rs752010 0.714 rs7552928 chr1:42086664 C/T cg06885757 chr1:42089581 HIVEP3 0.31 6.5 0.33 2.9e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs6952808 0.929 rs2280550 chr7:1976556 G/A cg14004847 chr7:1930337 MAD1L1 -0.43 -6.19 -0.32 1.74e-9 Bipolar disorder and schizophrenia; LIHC cis rs10779751 0.575 rs2791655 chr1:11128654 A/G cg08854313 chr1:11322531 MTOR -0.62 -9.58 -0.46 2.09e-19 Body mass index; LIHC trans rs2224539 0.605 rs12624333 chr20:38467979 C/T cg21682942 chr2:85824657 RNF181 0.36 6.05 0.31 3.76e-9 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs568617 0.859 rs1204650 chr11:65645580 A/C cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.44 -0.33 4.17e-10 Crohn's disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23202053 chr19:1815917 REXO1 -0.38 -6.32 -0.32 8.05e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2180341 1.000 rs4897207 chr6:127605898 C/T cg27446573 chr6:127587934 RNF146 1.02 15.66 0.65 4.93e-42 Breast cancer; LIHC cis rs8017423 0.967 rs61996919 chr14:90701803 A/C cg14092571 chr14:90743983 NA -0.38 -5.96 -0.31 6.43e-9 Mortality in heart failure; LIHC cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg21644426 chr2:191273491 MFSD6 -0.5 -6.84 -0.35 3.77e-11 Pulse pressure; LIHC cis rs77861329 1.000 rs17051957 chr3:52099441 A/G cg08692210 chr3:52188851 WDR51A 0.82 8.06 0.4 1.32e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs600806 0.778 rs4970767 chr1:110015183 G/A cg08911820 chr1:110026001 ATXN7L2 -0.58 -7.38 -0.37 1.18e-12 Intelligence (multi-trait analysis); LIHC trans rs575908 0.640 rs12121676 chr1:177904751 A/G ch.2.121457425R chr2:121740955 GLI2 -0.4 -6.5 -0.33 2.89e-10 Breast cancer; LIHC cis rs7552404 0.921 rs10873685 chr1:76218818 A/C cg03433033 chr1:76189801 ACADM 0.67 9.26 0.45 2.31e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7131987 0.650 rs7301398 chr12:29455390 G/T cg14222432 chr12:29376421 FAR2 0.35 6.74 0.34 6.68e-11 QT interval; LIHC cis rs367615 0.659 rs13435970 chr5:108884660 C/T cg17395555 chr5:108820864 NA 0.32 6.46 0.33 3.62e-10 Colorectal cancer (SNP x SNP interaction); LIHC cis rs7927771 0.864 rs4752838 chr11:47466006 G/A cg18512352 chr11:47633146 NA -0.26 -5.95 -0.31 6.58e-9 Subjective well-being; LIHC cis rs611744 0.647 rs2594357 chr8:109255989 A/G cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC trans rs1728785 1.000 rs1170436 chr16:68607486 T/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.37 0.33 6.01e-10 Ulcerative colitis; LIHC cis rs7572733 0.555 rs700671 chr2:198690001 T/C cg03934865 chr2:198174659 NA 0.45 6.47 0.33 3.42e-10 Dermatomyositis; LIHC trans rs11098499 0.866 rs13105020 chr4:120285688 G/T cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs6762477 0.748 rs11711407 chr3:50225029 A/G cg21467203 chr3:49911342 NA 0.35 6.29 0.32 9.76e-10 Menarche (age at onset); LIHC cis rs13108904 0.517 rs7671242 chr4:1339875 G/A cg22903657 chr4:1355424 KIAA1530 -0.41 -5.98 -0.31 5.71e-9 Obesity-related traits; LIHC cis rs4407350 1.000 rs5765723 chr22:44921554 C/T cg26276947 chr22:44892394 LDOC1L 0.33 6.22 0.32 1.41e-9 Intelligence (multi-trait analysis); LIHC cis rs9911578 1.000 rs2531734 chr17:56550804 T/C cg12560992 chr17:57184187 TRIM37 -0.96 -17.27 -0.68 1.68e-48 Intelligence (multi-trait analysis); LIHC cis rs3741404 0.825 rs60452247 chr11:63981507 G/A cg24431193 chr11:63883947 FLRT1;MACROD1 -0.38 -5.89 -0.3 9.44e-9 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24335600 chr1:241682994 FH -0.49 -6.89 -0.35 2.69e-11 Pancreatic cancer; LIHC trans rs7714584 0.793 rs11958146 chr5:150254158 A/G cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs875971 0.660 rs13224319 chr7:66007363 A/G cg11764359 chr7:65958608 NA 0.72 11.04 0.51 1.9e-24 Aortic root size; LIHC cis rs644148 0.836 rs2571112 chr19:45000319 T/A cg15540054 chr19:45004280 ZNF180 -0.77 -11.57 -0.53 2.29e-26 Personality dimensions; LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg19635926 chr16:89946313 TCF25 0.52 7.02 0.36 1.17e-11 Skin colour saturation; LIHC cis rs1868673 0.503 rs13326592 chr3:150240342 T/G cg10752315 chr3:150238463 NA 0.3 5.92 0.3 7.73e-9 Waist circumference; LIHC cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg05665937 chr4:1216051 CTBP1 0.39 6.02 0.31 4.46e-9 Obesity-related traits; LIHC cis rs12579753 1.000 rs7956826 chr12:82173365 A/G cg07988820 chr12:82153109 PPFIA2 -0.49 -6.17 -0.32 1.94e-9 Resting heart rate; LIHC cis rs4803468 0.967 rs16975238 chr19:41944985 T/A cg09537434 chr19:41945824 ATP5SL 1.02 20.83 0.75 8.37e-63 Height; LIHC cis rs5769707 0.521 rs6009805 chr22:50058715 T/C cg01652190 chr22:50026171 C22orf34 -0.29 -6.34 -0.32 7.24e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1494950 1.000 rs28611277 chr4:14981659 G/A cg12377275 chr4:15005593 CPEB2 -0.79 -6.71 -0.34 8.25e-11 Political ideology; LIHC cis rs477692 1.000 rs506274 chr10:131409392 T/A cg05714579 chr10:131428358 MGMT 0.46 7.53 0.38 4.47e-13 Response to temozolomide; LIHC cis rs1355223 0.902 rs1597962 chr11:34727172 T/C cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.32 -0.32 8.21e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7027203 0.797 rs57882762 chr9:96580825 T/G cg14598338 chr9:96623480 NA -0.32 -6.31 -0.32 8.44e-10 DNA methylation (variation); LIHC cis rs2576037 0.526 rs1893427 chr18:44434987 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.73e-12 Personality dimensions; LIHC trans rs877282 1.000 rs11253370 chr10:773712 G/A cg22713356 chr15:30763199 NA 1.28 11.42 0.53 8.49e-26 Uric acid levels; LIHC cis rs4908768 0.501 rs6669503 chr1:8564301 C/G cg20416874 chr1:8611966 RERE -0.65 -13.6 -0.59 5.48e-34 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs2243480 1.000 rs437889 chr7:65509234 G/A cg10756647 chr7:56101905 PSPH 1.08 13.46 0.59 2e-33 Diabetic kidney disease; LIHC cis rs2425143 1.000 rs45595739 chr20:34320759 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.85 -0.3 1.13e-8 Blood protein levels; LIHC cis rs1882538 0.503 rs13240997 chr7:133135373 C/A cg10665199 chr7:133106180 EXOC4 0.53 8.19 0.4 5.39e-15 Intelligence (multi-trait analysis); LIHC cis rs11971779 0.680 rs1133067 chr7:139053069 G/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2832191 0.740 rs13048618 chr21:30458684 A/G cg08807101 chr21:30365312 RNF160 0.79 11.9 0.54 1.44e-27 Dental caries; LIHC cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg03517284 chr6:25882590 NA -0.64 -7.91 -0.39 3.48e-14 Intelligence (multi-trait analysis); LIHC cis rs12819124 0.502 rs10875718 chr12:48411102 G/T cg21466736 chr12:48725269 NA -0.57 -8.05 -0.4 1.36e-14 Glycated hemoglobin levels; LIHC cis rs9811920 0.609 rs793462 chr3:99616461 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -10.09 -0.48 3.92e-21 Platelet count; LIHC trans rs11722228 0.522 rs881641 chr4:10133747 G/A cg26043149 chr18:55253948 FECH 1.02 15.09 0.63 8.22e-40 Gout;Urate levels;Serum uric acid levels; LIHC trans rs12310956 0.532 rs11052935 chr12:33970946 C/T cg26384229 chr12:38710491 ALG10B 0.49 6.71 0.34 8.25e-11 Morning vs. evening chronotype; LIHC cis rs12079745 0.590 rs12097682 chr1:169333438 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.81 -7.12 -0.36 6.37e-12 QT interval; LIHC cis rs62158211 1.000 rs4618068 chr2:114109355 C/T cg17784749 chr2:114082611 LOC440839 0.61 7.26 0.37 2.68e-12 Sleep duration (oversleepers vs undersleepers);Sleep traits (multi-trait analysis);Sleep duration; LIHC cis rs10905065 0.965 rs10795520 chr10:5764160 G/A cg11519256 chr10:5708881 ASB13 0.45 5.92 0.31 7.67e-9 Menopause (age at onset); LIHC cis rs7312933 0.670 rs10880269 chr12:42606135 C/T cg01256987 chr12:42539512 GXYLT1 -0.4 -6.74 -0.34 6.78e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4819052 0.959 rs8130866 chr21:46672112 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.7 9.63 0.46 1.39e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs11055008 0.620 rs12816452 chr12:12833006 A/T cg09462578 chr12:12878428 APOLD1 -0.48 -7.65 -0.38 2.11e-13 Pulse pressure; LIHC cis rs67478160 0.643 rs2223937 chr14:104286380 A/G cg08213375 chr14:104286397 PPP1R13B 0.65 12.56 0.56 4.96e-30 Schizophrenia; LIHC cis rs1062177 1.000 rs2964612 chr5:151198750 G/A cg00977110 chr5:151150581 G3BP1 0.54 6.74 0.34 6.65e-11 Preschool internalizing problems; LIHC cis rs8103278 1.000 rs17571725 chr19:46290822 C/T cg02376097 chr19:46275166 DMPK -0.44 -6.81 -0.35 4.43e-11 Coronary artery disease; LIHC cis rs903552 1.000 rs8043379 chr15:102005837 A/G cg00659931 chr15:102010125 PCSK6 -0.46 -6.2 -0.32 1.63e-9 Diabetic kidney disease; LIHC cis rs17401966 1.000 rs12407992 chr1:10311983 A/C cg19773385 chr1:10388646 KIF1B -0.48 -8.29 -0.41 2.64e-15 Hepatocellular carcinoma; LIHC cis rs2302777 0.507 rs9889716 chr17:38108298 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.47 -7.0 -0.35 1.32e-11 Multiple myeloma (hyperdiploidy); LIHC cis rs7829975 0.686 rs907180 chr8:8702827 A/G cg06636001 chr8:8085503 FLJ10661 0.38 6.15 0.32 2.19e-9 Mood instability; LIHC cis rs4820539 0.966 rs2301554 chr22:23484254 A/C cg14186256 chr22:23484241 RTDR1 0.97 20.95 0.75 2.8e-63 Bone mineral density; LIHC cis rs7927771 0.929 rs66749409 chr11:47568074 C/T cg20135002 chr11:47629003 NA -0.57 -10.07 -0.48 4.6e-21 Subjective well-being; LIHC cis rs9612 1.000 rs58896392 chr19:44269142 G/A cg08581076 chr19:44259116 C19orf61 0.62 7.48 0.37 6.35e-13 Exhaled nitric oxide output; LIHC cis rs7633770 0.786 rs4683256 chr3:46683617 T/G cg11219411 chr3:46661640 NA 0.45 8.02 0.4 1.73e-14 Coronary artery disease; LIHC cis rs6089584 0.861 rs2180302 chr20:60576369 A/G cg06108461 chr20:60628389 TAF4 -0.89 -14.02 -0.6 1.4e-35 Body mass index; LIHC cis rs11758351 0.660 rs11753655 chr6:26220109 C/T cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.63 -0.56 2.82e-30 Alzheimer's disease; LIHC cis rs3770081 1.000 rs11899576 chr2:86256193 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -9.29 -0.45 1.79e-18 Facial emotion recognition (sad faces); LIHC cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg11062466 chr8:58055876 NA 0.5 6.31 0.32 8.66e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg11062466 chr8:58055876 NA 0.5 7.42 0.37 9.65e-13 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 25.06 0.8 2.12e-79 Prudent dietary pattern; LIHC cis rs6835098 0.961 rs2078475 chr4:174098226 A/C cg27433088 chr4:174089019 GALNT7 -0.4 -5.94 -0.31 6.84e-9 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs2637266 1.000 rs7900616 chr10:78367075 C/T cg18941641 chr10:78392320 NA 0.27 5.72 0.3 2.35e-8 Pulmonary function; LIHC cis rs240764 0.580 rs4839789 chr6:101233235 T/A cg09795085 chr6:101329169 ASCC3 -0.42 -5.86 -0.3 1.09e-8 Neuroticism; LIHC cis rs10503871 0.545 rs10955031 chr8:30475926 A/G cg26383811 chr8:30366931 RBPMS 0.43 6.93 0.35 2.1e-11 Metabolite levels (X-11787); LIHC cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg13409248 chr3:40428643 ENTPD3 0.49 8.33 0.41 1.95e-15 Renal cell carcinoma; LIHC cis rs6815814 0.731 rs11096956 chr4:38776180 G/T cg06935464 chr4:38784597 TLR10 0.38 6.05 0.31 3.75e-9 Breast cancer; LIHC trans rs877282 0.755 rs2790388 chr10:786084 T/C cg22713356 chr15:30763199 NA 1.21 11.49 0.53 4.56e-26 Uric acid levels; LIHC trans rs10511404 1.000 rs11714961 chr3:120510144 G/C cg09889680 chr22:21922804 UBE2L3 -0.48 -6.15 -0.32 2.22e-9 Tumor necrosis factor alpha levels; LIHC cis rs8177253 0.530 rs8177177 chr3:133463195 A/G cg16262614 chr3:133464971 TF 0.32 7.18 0.36 4.5e-12 Iron status biomarkers; LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.6 -8.64 -0.42 2.21e-16 Lymphocyte counts; LIHC cis rs12048904 0.964 rs17123467 chr1:101331760 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.53 8.45 0.42 8.38e-16 Multiple sclerosis; LIHC cis rs919433 0.647 rs1979239 chr2:198498316 T/G cg00792783 chr2:198669748 PLCL1 0.39 5.83 0.3 1.31e-8 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs240764 0.658 rs11155618 chr6:101181811 C/T cg12253828 chr6:101329408 ASCC3 -0.39 -5.97 -0.31 6.04e-9 Neuroticism; LIHC cis rs6088580 0.634 rs1205336 chr20:32926336 G/A cg08999081 chr20:33150536 PIGU -0.67 -13.3 -0.58 8.38e-33 Glomerular filtration rate (creatinine); LIHC cis rs7772486 0.790 rs9376968 chr6:146180364 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.74 0.3 2.12e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7715806 0.500 rs2291630 chr5:75013356 G/A cg19683494 chr5:74908142 NA 0.68 7.91 0.39 3.55e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1814175 0.645 rs10128563 chr11:50023681 T/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC trans rs11098499 0.604 rs12642411 chr4:120580525 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.59 0.42 3.17e-16 Corneal astigmatism; LIHC cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg27572855 chr1:25598939 RHD 0.4 8.61 0.42 2.62e-16 Plateletcrit;Mean corpuscular volume; LIHC cis rs4803468 1.000 rs4803463 chr19:41911040 C/G cg09537434 chr19:41945824 ATP5SL -1.01 -21.3 -0.76 1.14e-64 Height; LIHC cis rs924607 0.931 rs1709556 chr5:637058 A/G cg04476341 chr5:669733 TPPP 0.38 8.66 0.42 1.96e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2404602 0.692 rs3816266 chr15:76993835 T/G cg03037974 chr15:76606532 NA 0.74 14.5 0.62 1.74e-37 Blood metabolite levels; LIHC cis rs9303401 0.614 rs34550282 chr17:57092788 G/A cg25039879 chr17:56429692 SUPT4H1 0.76 8.75 0.43 1.02e-16 Cognitive test performance; LIHC cis rs2005 0.582 rs3800404 chr6:35137870 G/T cg13137465 chr6:34857473 ANKS1A -0.54 -6.11 -0.31 2.77e-9 Obesity-related traits; LIHC cis rs365132 1.000 rs601923 chr5:176417386 C/G cg16309518 chr5:176445507 NA -0.57 -11.41 -0.52 9.33e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs2749592 0.531 rs1208559 chr10:38221370 T/C cg18963800 chr10:38644991 HSD17B7P2 0.37 5.77 0.3 1.78e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs748404 0.660 rs2467742 chr15:43750237 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.88 0.39 4.54e-14 Lung cancer; LIHC cis rs7772486 0.875 rs10457796 chr6:146416087 T/G cg23711669 chr6:146136114 FBXO30 0.57 9.78 0.47 4.35e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs11190604 1.000 rs10883492 chr10:102206089 G/A cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2115630 0.967 rs10438428 chr15:85330745 C/T cg12501888 chr15:85177176 SCAND2 -0.48 -7.5 -0.38 5.53e-13 P wave terminal force; LIHC cis rs1823913 1.000 rs11691372 chr2:192114678 A/C cg12404831 chr2:192114017 MYO1B -0.34 -6.76 -0.34 5.93e-11 Obesity-related traits; LIHC cis rs71446622 0.506 rs36090150 chr13:113432388 T/C cg08557188 chr13:113420371 ATP11A -0.79 -5.93 -0.31 7.5e-9 Mean corpuscular volume; LIHC cis rs6089584 0.888 rs6061405 chr20:60617033 A/G cg13770153 chr20:60521292 NA -0.33 -6.72 -0.34 7.51e-11 Body mass index; LIHC cis rs763121 0.853 rs5750668 chr22:39079964 T/C cg06022373 chr22:39101656 GTPBP1 0.65 11.24 0.52 3.79e-25 Menopause (age at onset); LIHC cis rs644799 0.710 rs10831427 chr11:95508383 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.78 13.29 0.58 8.97e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1395 0.634 rs72817542 chr2:27526681 C/G cg22903471 chr2:27725779 GCKR -0.44 -6.31 -0.32 8.43e-10 Blood metabolite levels; LIHC cis rs9443189 0.615 rs602873 chr6:76323818 T/A cg01950844 chr6:76311363 SENP6 0.88 11.02 0.51 2.2e-24 Prostate cancer; LIHC cis rs4925386 0.625 rs3810550 chr20:60912117 C/T cg06026331 chr20:60912101 LAMA5 0.65 9.39 0.45 8.73e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs4268898 0.896 rs2702042 chr2:24546542 C/T cg06627628 chr2:24431161 ITSN2 -0.58 -8.27 -0.41 3.02e-15 Asthma; LIHC cis rs11971779 0.527 rs1076349 chr7:139126494 A/G cg07862535 chr7:139043722 LUC7L2 0.59 9.92 0.47 1.46e-20 Diisocyanate-induced asthma; LIHC cis rs4423214 1.000 rs2276362 chr11:71174452 A/G cg24826892 chr11:71159390 DHCR7 0.49 6.3 0.32 9.04e-10 Vitamin D levels; LIHC cis rs4716602 0.596 rs10265482 chr7:156160655 C/G cg16983916 chr7:156159713 NA -0.32 -5.75 -0.3 2.01e-8 Anti-saccade response; LIHC cis rs9486715 0.838 rs4839840 chr6:96941149 T/C cg06623918 chr6:96969491 KIAA0776 0.84 14.88 0.63 5.67e-39 Headache; LIHC cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC cis rs35306767 0.715 rs12777801 chr10:1036285 T/A cg20503657 chr10:835505 NA 0.81 7.5 0.38 5.4e-13 Eosinophil percentage of granulocytes; LIHC cis rs7582720 0.943 rs72926799 chr2:203828192 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7772486 0.817 rs9322047 chr6:146400394 G/A cg23711669 chr6:146136114 FBXO30 0.58 10.0 0.48 8.27e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs2274273 0.840 rs11626751 chr14:55835227 T/C cg01864836 chr14:55583639 NA -0.38 -6.73 -0.34 7.02e-11 Protein biomarker; LIHC cis rs7408868 1.000 rs4809030 chr19:15273381 A/G cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg18252515 chr7:66147081 NA -1.24 -15.92 -0.65 4.31e-43 Diabetic kidney disease; LIHC cis rs644799 0.648 rs1255181 chr11:95472148 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.62 10.19 0.48 1.85e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14626525 chr9:140731445 MIR602 0.43 6.4 0.33 5.14e-10 Longevity; LIHC cis rs11098499 0.820 rs6534140 chr4:120455311 C/T cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs9790314 1.000 rs9850455 chr3:161017192 G/A cg03342759 chr3:160939853 NMD3 -0.76 -10.83 -0.51 1.03e-23 Morning vs. evening chronotype; LIHC cis rs6461049 0.638 rs3778994 chr7:2175855 G/T cg21782813 chr7:2030301 MAD1L1 0.35 6.16 0.32 2.08e-9 Schizophrenia; LIHC cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg05590025 chr7:65112418 INTS4L2 0.61 6.65 0.34 1.16e-10 Diabetic kidney disease; LIHC cis rs9733 0.596 rs2867301 chr1:150653795 C/T cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Tonsillectomy; LIHC cis rs9303401 0.614 rs68100606 chr17:56500898 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.86 11.2 0.52 5.32e-25 Cognitive test performance; LIHC cis rs950169 0.724 rs11632668 chr15:84948687 T/C cg03959625 chr15:84868606 LOC388152 0.47 6.76 0.34 6.14e-11 Schizophrenia; LIHC cis rs7945718 0.621 rs61879826 chr11:12684486 T/C cg25843174 chr11:12811716 TEAD1 0.34 7.8 0.39 7.4e-14 Educational attainment (years of education); LIHC cis rs11212260 0.655 rs7949914 chr11:107269467 C/G cg25435332 chr11:107328525 CWF19L2 0.81 8.76 0.43 8.88e-17 IgG glycosylation; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01114405 chr6:504249 EXOC2 0.4 6.03 0.31 4.18e-9 Longevity; LIHC cis rs4925386 1.000 rs4925389 chr20:60922512 G/A cg03945807 chr20:60948434 NA -0.37 -6.64 -0.34 1.25e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs6089829 0.889 rs6062773 chr20:61663262 G/C cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs9326248 0.539 rs7120565 chr11:117042949 T/C cg26566898 chr11:117069891 TAGLN 0.39 6.05 0.31 3.79e-9 Blood protein levels; LIHC cis rs7937890 0.559 rs4369365 chr11:14444515 C/G cg02886208 chr11:14281011 SPON1 -0.51 -7.09 -0.36 7.96e-12 Mitochondrial DNA levels; LIHC cis rs11229555 0.645 rs11229431 chr11:58181253 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs11690935 0.531 rs4280428 chr2:172813219 G/A cg13550731 chr2:172543902 DYNC1I2 0.42 5.91 0.3 8.15e-9 Schizophrenia; LIHC cis rs9790314 0.723 rs1026572 chr3:160887654 A/G cg03342759 chr3:160939853 NMD3 -0.74 -10.5 -0.49 1.57e-22 Morning vs. evening chronotype; LIHC cis rs2257205 0.667 rs16943134 chr17:56681389 A/G cg12560992 chr17:57184187 TRIM37 0.71 7.86 0.39 5.22e-14 Pancreatic cancer; LIHC cis rs11122272 0.705 rs2486742 chr1:231507254 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -10.57 -0.5 8.95e-23 Hemoglobin concentration; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07017693 chr10:71912317 SAR1A 0.52 6.39 0.33 5.47e-10 Systolic blood pressure; LIHC cis rs35146811 0.806 rs1534310 chr7:99699169 A/T cg13334819 chr7:99746414 C7orf59 -0.6 -8.48 -0.42 6.68e-16 Coronary artery disease; LIHC cis rs17818399 0.645 rs35870739 chr2:46784231 A/C cg02822958 chr2:46747628 ATP6V1E2 0.48 7.06 0.36 9.45e-12 Height; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg02850329 chr1:24829455 RCAN3 -0.48 -6.27 -0.32 1.1e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs3736485 0.966 rs12101730 chr15:51800733 C/T cg08986416 chr15:51914746 DMXL2 -0.4 -5.99 -0.31 5.18e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2050392 0.624 rs303450 chr10:30725337 C/A cg18806716 chr10:30721971 MAP3K8 -0.41 -5.89 -0.3 9.43e-9 Inflammatory bowel disease; LIHC cis rs7412746 0.658 rs12405726 chr1:150956128 G/A cg18016565 chr1:150552671 MCL1 0.53 9.56 0.46 2.35e-19 Melanoma; LIHC cis rs2933343 1.000 rs1683782 chr3:128640277 A/G cg25356066 chr3:128598488 ACAD9 0.53 7.08 0.36 8.1e-12 IgG glycosylation; LIHC cis rs6733011 0.508 rs12712041 chr2:99522059 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.43 -6.2 -0.32 1.58e-9 Bipolar disorder; LIHC cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg24531977 chr5:56204891 C5orf35 0.74 10.43 0.49 2.73e-22 Initial pursuit acceleration; LIHC cis rs7647973 1.000 rs62259947 chr3:49439924 T/C cg07636037 chr3:49044803 WDR6 -0.52 -6.22 -0.32 1.43e-9 Menarche (age at onset); LIHC cis rs11702148 0.552 rs3787708 chr21:34906039 C/T cg14850771 chr21:34775459 IFNGR2 0.48 7.99 0.4 2.09e-14 Mean corpuscular hemoglobin; LIHC cis rs1023500 0.573 rs133378 chr22:42467695 G/C cg04733989 chr22:42467013 NAGA 0.66 9.69 0.46 9.09e-20 Schizophrenia; LIHC cis rs903552 0.932 rs2172851 chr15:102012626 C/T cg00659931 chr15:102010125 PCSK6 -0.48 -6.47 -0.33 3.45e-10 Diabetic kidney disease; LIHC cis rs965469 1.000 rs6051831 chr20:3373712 G/T cg25506879 chr20:3388711 C20orf194 0.54 6.56 0.33 2.04e-10 IFN-related cytopenia; LIHC cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg18404041 chr3:52824283 ITIH1 -0.55 -9.21 -0.45 3.35e-18 Electroencephalogram traits; LIHC cis rs10256972 0.804 rs10275585 chr7:1017339 T/C cg04025307 chr7:1156635 C7orf50 0.41 6.24 0.32 1.32e-9 Longevity;Endometriosis; LIHC cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -13.92 -0.6 3.18e-35 Alzheimer's disease; LIHC cis rs3096299 0.933 rs889576 chr16:89429653 A/G cg08822215 chr16:89438651 ANKRD11 0.45 7.2 0.36 3.79e-12 Multiple myeloma (IgH translocation); LIHC cis rs11229555 1.000 rs2275993 chr11:58379987 A/G cg15696309 chr11:58395628 NA -0.73 -8.95 -0.44 2.24e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9325144 0.560 rs11182930 chr12:38633693 A/T cg26384229 chr12:38710491 ALG10B -0.61 -8.48 -0.42 6.86e-16 Morning vs. evening chronotype; LIHC cis rs7772486 0.875 rs854146 chr6:146341033 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.81 0.3 1.4e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs11098499 0.588 rs6534149 chr4:120559292 T/G cg25214090 chr10:38739885 LOC399744 -0.43 -7.0 -0.35 1.39e-11 Corneal astigmatism; LIHC cis rs4819052 0.851 rs2838832 chr21:46664904 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.72 -11.05 -0.51 1.79e-24 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9517302 0.847 rs9517300 chr13:99095057 T/C cg22223119 chr13:99095684 FARP1 -0.79 -12.98 -0.57 1.36e-31 Obesity-related traits; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg16466278 chr15:43429893 TMEM62 0.46 7.03 0.36 1.15e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.8 -14.87 -0.63 6.11e-39 Prudent dietary pattern; LIHC cis rs72781680 0.699 rs72796125 chr2:23919169 C/T cg08917208 chr2:24149416 ATAD2B 0.97 8.16 0.4 6.38e-15 Lymphocyte counts; LIHC cis rs7546668 1.000 rs4646090 chr1:15822073 A/G cg11706911 chr1:15910989 AGMAT 0.44 6.8 0.35 4.68e-11 Glomerular filtration rate (creatinine); LIHC cis rs6912958 0.702 rs6906769 chr6:88235949 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.45 -7.9 -0.39 3.93e-14 Monocyte percentage of white cells; LIHC cis rs8060686 0.591 rs255054 chr16:68017356 A/G cg05110241 chr16:68378359 PRMT7 -0.52 -5.76 -0.3 1.87e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs6500602 0.929 rs6500603 chr16:4497537 G/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.42 5.84 0.3 1.19e-8 Schizophrenia; LIHC cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -10.15 -0.48 2.43e-21 Platelet count; LIHC cis rs11098499 0.863 rs6534139 chr4:120449456 A/G cg09307838 chr4:120376055 NA -0.73 -10.87 -0.51 7.65e-24 Corneal astigmatism; LIHC cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg03874509 chr1:107600012 PRMT6 0.71 11.35 0.52 1.48e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4853036 1.000 rs11903034 chr2:70060278 T/G cg02498382 chr2:70120550 SNRNP27 -0.36 -5.75 -0.3 1.97e-8 Colorectal or endometrial cancer; LIHC cis rs8060686 0.516 rs7193701 chr16:68185160 A/G cg05110241 chr16:68378359 PRMT7 0.47 6.1 0.31 2.93e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs10870270 0.956 rs11146325 chr10:133767529 A/G cg08754478 chr10:133766260 PPP2R2D -0.54 -8.03 -0.4 1.58e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs12477438 0.765 rs6735801 chr2:99657995 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.67 -0.5 4.06e-23 Chronic sinus infection; LIHC cis rs7131987 0.903 rs10843373 chr12:29420608 A/T cg21522988 chr12:29376872 FAR2 0.29 6.73 0.34 7.34e-11 QT interval; LIHC cis rs2842992 0.672 rs7738253 chr6:160193917 G/T cg11366901 chr6:160182831 ACAT2 0.88 14.19 0.61 3.04e-36 Age-related macular degeneration (geographic atrophy); LIHC cis rs10791097 0.720 rs6590515 chr11:130733365 A/G cg12179176 chr11:130786555 SNX19 -0.8 -12.93 -0.57 2.1e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg00343986 chr7:65444356 GUSB 0.44 6.26 0.32 1.18e-9 Calcium levels; LIHC cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg05564831 chr3:52568323 NT5DC2 0.35 5.77 0.3 1.82e-8 Bipolar disorder; LIHC cis rs769267 0.896 rs7250893 chr19:19625547 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.4 6.08 0.31 3.17e-9 Tonsillectomy; LIHC cis rs240764 0.595 rs1039033 chr6:101191397 C/T cg09795085 chr6:101329169 ASCC3 -0.52 -7.31 -0.37 1.91e-12 Neuroticism; LIHC cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg12310025 chr6:25882481 NA -0.62 -7.68 -0.38 1.71e-13 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.534 rs1844526 chr12:34102780 G/A cg26384229 chr12:38710491 ALG10B 0.53 7.29 0.37 2.14e-12 Morning vs. evening chronotype; LIHC cis rs951366 0.903 rs823114 chr1:205719532 G/A cg14159672 chr1:205819179 PM20D1 0.32 5.84 0.3 1.25e-8 Menarche (age at onset); LIHC cis rs9858542 1.000 rs11709525 chr3:49690496 C/T cg03060546 chr3:49711283 APEH -0.63 -8.47 -0.42 7.5e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs796364 1.000 rs4410273 chr2:200818258 T/C cg23649088 chr2:200775458 C2orf69 0.5 6.04 0.31 3.98e-9 Schizophrenia; LIHC cis rs17826219 0.706 rs8071236 chr17:29100002 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.18 0.4 5.73e-15 Body mass index; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.45e-13 Prudent dietary pattern; LIHC cis rs7542091 0.635 rs7550733 chr1:210044968 G/A cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg21171335 chr12:122356390 WDR66 0.57 9.65 0.46 1.16e-19 Mean corpuscular volume; LIHC cis rs13108904 0.775 rs2279282 chr4:1216033 G/C cg19318889 chr4:1322082 MAEA 0.42 6.27 0.32 1.1e-9 Obesity-related traits; LIHC cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg08219700 chr8:58056026 NA 0.5 6.34 0.32 7.14e-10 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg18538332 chr22:24372958 LOC391322 -0.65 -9.56 -0.46 2.33e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7772486 0.790 rs9497435 chr6:146265340 C/A cg23711669 chr6:146136114 FBXO30 -0.62 -10.87 -0.51 7.68e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs9914988 0.943 rs2043031 chr17:27085564 A/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.96 -0.35 1.79e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg08490173 chr5:114880508 FEM1C -0.54 -6.17 -0.32 1.95e-9 Systolic blood pressure; LIHC cis rs7772486 0.846 rs9373482 chr6:146363123 A/C cg13319975 chr6:146136371 FBXO30 -0.36 -6.02 -0.31 4.44e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1059312 0.966 rs7135968 chr12:129280066 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.73 -14.43 -0.62 3.3e-37 Systemic lupus erythematosus; LIHC cis rs425277 1.000 rs262670 chr1:2082458 C/T cg24578937 chr1:2090814 PRKCZ 0.5 9.06 0.44 1.06e-17 Height; LIHC cis rs12995491 0.933 rs13023008 chr2:88530933 G/A cg14558114 chr2:88469736 THNSL2 -0.38 -5.85 -0.3 1.18e-8 Response to metformin (IC50); LIHC cis rs10870270 0.957 rs9971084 chr10:133788747 G/C cg08754478 chr10:133766260 PPP2R2D -0.53 -7.77 -0.39 9.14e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs3857067 0.806 rs17302467 chr4:95112056 T/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs9457247 1.000 rs364451 chr6:167384756 G/A cg12798992 chr6:167411361 FGFR1OP 0.52 8.11 0.4 9.34e-15 Crohn's disease; LIHC cis rs807029 0.533 rs3740487 chr10:102750783 C/A cg27255678 chr10:102756921 LZTS2 0.51 7.31 0.37 1.89e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4843747 0.671 rs4072871 chr16:88106614 C/T cg00677901 chr16:88017247 BANP 0.53 8.1 0.4 9.53e-15 Menopause (age at onset); LIHC cis rs11711311 1.000 rs9863050 chr3:113508888 C/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.47 9.0 0.44 1.57e-17 IgG glycosylation; LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg21724239 chr8:58056113 NA 0.58 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs11018874 0.597 rs4268468 chr11:89886284 C/T cg23743573 chr11:89867420 NAALAD2 0.38 5.75 0.3 1.98e-8 White blood cell types; LIHC cis rs2439831 1.000 rs2253708 chr15:43797273 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.64 9.07 0.44 9.26e-18 Lung cancer in ever smokers; LIHC cis rs11212260 0.512 rs17587175 chr11:107187510 G/A cg25435332 chr11:107328525 CWF19L2 0.76 7.13 0.36 6.18e-12 IgG glycosylation; LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg20607798 chr8:58055168 NA 0.63 8.13 0.4 8.2e-15 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.790 rs11760 chr6:146205973 G/T cg23711669 chr6:146136114 FBXO30 0.64 11.09 0.51 1.23e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs798554 0.591 rs1182156 chr7:2901084 G/T cg13628971 chr7:2884303 GNA12 0.44 7.69 0.38 1.54e-13 Height; LIHC cis rs208520 1.000 rs12191403 chr6:66978137 C/T cg07460842 chr6:66804631 NA 0.67 7.3 0.37 2.1e-12 Exhaled nitric oxide output; LIHC cis rs11122272 0.735 rs2790883 chr1:231532726 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.18e-18 Hemoglobin concentration; LIHC cis rs600806 0.850 rs4970752 chr1:109930852 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC cis rs10744422 0.858 rs10773627 chr12:123311853 A/G cg25930673 chr12:123319894 HIP1R -0.83 -10.76 -0.5 1.92e-23 Schizophrenia; LIHC cis rs4788570 0.578 rs7204992 chr16:71658444 G/A cg06353428 chr16:71660113 MARVELD3 1.45 15.62 0.65 6.99e-42 Intelligence (multi-trait analysis); LIHC trans rs3812049 0.784 rs2568928 chr5:127487603 C/T cg16011800 chr17:1958478 HIC1 0.51 7.34 0.37 1.53e-12 Lymphocyte counts;Red cell distribution width; LIHC cis rs11608355 0.515 rs1045582 chr12:109915727 G/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs6445975 0.715 rs13320332 chr3:58268344 A/T cg23715586 chr3:58305044 RPP14 -0.36 -6.11 -0.31 2.72e-9 Systemic lupus erythematosus; LIHC cis rs7918232 0.882 rs10829190 chr10:27409555 C/T cg14442939 chr10:27389572 ANKRD26 0.72 7.07 0.36 8.65e-12 Breast cancer; LIHC cis rs9399137 0.507 rs13197750 chr6:135312380 G/A cg24558204 chr6:135376177 HBS1L 0.61 10.4 0.49 3.53e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs7258465 1.000 rs271621 chr19:18631332 C/A cg10790698 chr19:18539756 SSBP4 -0.34 -7.09 -0.36 7.58e-12 Breast cancer; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs10492096 0.947 rs11064231 chr12:6604415 T/G cg13857086 chr12:6580257 VAMP1 0.58 6.14 0.31 2.32e-9 Hip geometry; LIHC cis rs9916302 0.800 rs8081220 chr17:37473157 A/C cg03013999 chr17:37608204 MED1 -0.35 -5.8 -0.3 1.5e-8 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg20607798 chr8:58055168 NA 0.69 7.73 0.39 1.25e-13 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.816 rs17050701 chr3:10041554 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs950169 0.845 rs4502182 chr15:84923520 A/G cg03959625 chr15:84868606 LOC388152 0.46 6.7 0.34 8.53e-11 Schizophrenia; LIHC cis rs875971 0.545 rs10950036 chr7:65818228 G/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.27 0.37 2.4e-12 Aortic root size; LIHC cis rs4474465 0.850 rs10899538 chr11:78237749 C/T cg27205649 chr11:78285834 NARS2 0.4 6.18 0.32 1.78e-9 Alzheimer's disease (survival time); LIHC cis rs9611519 1.000 rs9611519 chr22:41613188 C/T cg03806693 chr22:41940476 POLR3H -0.7 -7.82 -0.39 6.64e-14 Neuroticism; LIHC cis rs6450176 0.909 rs6884936 chr5:53293198 T/C ch.5.1024479R chr5:53302184 ARL15 -0.83 -15.23 -0.64 2.38e-40 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs3762637 1.000 rs10049131 chr3:122202102 A/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.83 -0.47 2.97e-20 LDL cholesterol levels; LIHC trans rs1814175 0.616 rs1722001 chr11:49894427 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.88 0.35 2.84e-11 Height; LIHC cis rs904251 0.523 rs2797798 chr6:37481437 C/T cg25019722 chr6:37503610 NA -0.32 -5.73 -0.3 2.19e-8 Cognitive performance; LIHC cis rs16828019 0.852 rs12048187 chr1:41616183 A/G cg20697417 chr1:41786797 NA 0.35 6.64 0.34 1.24e-10 Intelligence (multi-trait analysis); LIHC cis rs1790761 0.632 rs625978 chr11:67344664 C/T cg00290607 chr11:67383545 NA 0.38 5.77 0.3 1.76e-8 Mean corpuscular volume; LIHC cis rs1707322 0.717 rs3014246 chr1:46086077 C/T cg06784218 chr1:46089804 CCDC17 -0.42 -7.54 -0.38 4.39e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.16 0.79 6.11e-76 Prudent dietary pattern; LIHC cis rs34779708 0.966 rs35777088 chr10:35409048 T/C cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2976388 0.556 rs10956985 chr8:143818750 C/A cg06565975 chr8:143823917 SLURP1 -0.45 -8.31 -0.41 2.24e-15 Urinary tract infection frequency; LIHC cis rs7487075 0.780 rs12307969 chr12:46759057 G/C cg15584813 chr12:47219626 SLC38A4 0.32 5.77 0.3 1.74e-8 Itch intensity from mosquito bite; LIHC trans rs2727020 0.930 rs1164688 chr11:49290604 C/G cg03929089 chr4:120376271 NA 0.68 10.14 0.48 2.6e-21 Coronary artery disease; LIHC trans rs2262909 0.962 rs55728714 chr19:22262899 A/G cg05197062 chr11:11642011 GALNTL4 0.43 6.11 0.31 2.69e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs2070488 1.000 rs2268757 chr3:38505853 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.13 0.66 6.33e-44 Electrocardiographic conduction measures; LIHC cis rs12602486 1.000 rs78867692 chr17:42263873 G/C cg08193365 chr17:42277699 NA 1.0 7.03 0.36 1.14e-11 Glycated hemoglobin levels; LIHC cis rs2336384 1.000 rs6668386 chr1:12047233 T/C cg13216073 chr1:12042593 MFN2 0.42 6.36 0.33 6.29e-10 Platelet count; LIHC cis rs7937682 0.889 rs1784786 chr11:111486043 A/G cg09085632 chr11:111637200 PPP2R1B 0.89 10.56 0.5 9.3e-23 Primary sclerosing cholangitis; LIHC cis rs7238033 0.624 rs16978469 chr18:43305785 C/T cg20610511 chr18:43302872 SLC14A1 0.38 6.47 0.33 3.31e-10 Bladder cancer; LIHC cis rs4555082 0.957 rs3825762 chr14:105752404 T/C cg10792982 chr14:105748885 BRF1 0.42 5.73 0.3 2.17e-8 Mean platelet volume;Platelet distribution width; LIHC cis rs13126513 0.708 rs1491233 chr4:100476060 C/T cg05468953 chr4:100565104 NA 0.31 5.91 0.3 8.26e-9 Metabolite levels (MHPG); LIHC cis rs17539620 0.519 rs12665532 chr6:154835182 C/G cg20019720 chr6:154832845 CNKSR3 0.44 7.06 0.36 9.21e-12 Lipoprotein (a) levels; LIHC cis rs11785400 1.000 rs7002932 chr8:143738816 C/A cg10596483 chr8:143751796 JRK 0.52 8.46 0.42 7.64e-16 Schizophrenia; LIHC cis rs12744310 0.887 rs2363811 chr1:41791865 A/G cg03962019 chr1:41807865 NA 0.38 6.09 0.31 2.99e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1707322 0.682 rs12037459 chr1:46094959 T/G cg06784218 chr1:46089804 CCDC17 0.42 7.75 0.39 1.05e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs11098499 0.955 rs6815725 chr4:120158410 C/A cg25214090 chr10:38739885 LOC399744 0.53 8.02 0.4 1.68e-14 Corneal astigmatism; LIHC cis rs6088580 0.634 rs4911421 chr20:32998948 T/C cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs9640161 0.742 rs2108852 chr7:150019628 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.31 -0.41 2.26e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs16877106 0.744 rs73252577 chr4:25315616 G/A cg04796973 chr4:25314218 ZCCHC4 0.62 5.79 0.3 1.59e-8 Weight; LIHC cis rs372883 0.648 rs4817279 chr21:30638285 T/C cg24692254 chr21:30365293 RNF160 -0.52 -6.52 -0.33 2.51e-10 Pancreatic cancer; LIHC trans rs61931739 0.500 rs7310576 chr12:34474735 T/C cg26384229 chr12:38710491 ALG10B 0.61 7.52 0.38 5.01e-13 Morning vs. evening chronotype; LIHC cis rs1401999 1.000 rs4148571 chr3:183720576 A/C cg01324343 chr3:183735012 ABCC5 0.77 13.08 0.58 5.41e-32 Anterior chamber depth; LIHC cis rs67478160 0.634 rs2144079 chr14:104258884 C/T cg01849466 chr14:104193079 ZFYVE21 -0.51 -8.72 -0.43 1.26e-16 Schizophrenia; LIHC cis rs7927592 0.913 rs7925275 chr11:68290433 T/C cg16797656 chr11:68205561 LRP5 0.53 8.3 0.41 2.42e-15 Total body bone mineral density; LIHC cis rs1046896 0.562 rs2380172 chr17:80887719 C/A cg02711726 chr17:80685570 FN3KRP -0.39 -7.03 -0.36 1.15e-11 Glycated hemoglobin levels; LIHC cis rs7116495 0.867 rs2945921 chr11:71576480 T/G cg26138937 chr11:71823887 C11orf51 0.72 6.94 0.35 2.02e-11 Severe influenza A (H1N1) infection; LIHC cis rs1843834 1.000 rs1843834 chr2:225558042 A/G cg22509189 chr2:225307070 NA -0.54 -6.73 -0.34 7.25e-11 IgE levels in asthmatics (D.p. specific); LIHC cis rs6163 0.588 rs67506723 chr10:104509064 G/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.46 -6.85 -0.35 3.4e-11 Waist circumference;Hip circumference; LIHC cis rs6545883 0.860 rs6545847 chr2:61445333 C/T cg15711740 chr2:61764176 XPO1 0.42 5.87 0.3 1.03e-8 Tuberculosis; LIHC trans rs1034394 0.740 rs5999348 chr22:34818466 C/T cg02641517 chr3:54169983 CACNA2D3 -0.24 -6.1 -0.31 2.93e-9 Major depressive disorder; LIHC cis rs8180040 0.726 rs6774733 chr3:46991241 G/A cg02527881 chr3:46936655 PTH1R -0.34 -6.81 -0.35 4.34e-11 Colorectal cancer; LIHC cis rs7100689 0.646 rs1538815 chr10:82137670 A/G cg01528321 chr10:82214614 TSPAN14 0.85 11.49 0.53 4.76e-26 Post bronchodilator FEV1; LIHC cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg00750074 chr16:89608354 SPG7 0.51 8.47 0.42 7.57e-16 Multiple myeloma (IgH translocation); LIHC cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.37 0.45 9.93e-19 Bipolar disorder; LIHC cis rs9467773 1.000 rs9467779 chr6:26536687 A/T cg09904177 chr6:26538194 HMGN4 -0.65 -13.63 -0.59 4.48e-34 Intelligence (multi-trait analysis); LIHC cis rs78456975 0.689 rs13391992 chr2:1542153 G/A cg01028140 chr2:1542097 TPO -0.59 -7.45 -0.37 7.76e-13 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs6701037 1.000 rs6702010 chr1:175123858 C/A cg17845761 chr1:175162550 KIAA0040 -0.35 -5.8 -0.3 1.53e-8 Alcohol dependence; LIHC cis rs7216064 0.953 rs1599859 chr17:65837193 C/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.81e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs4253772 0.591 rs6007748 chr22:46657798 A/G cg09491104 chr22:46646882 C22orf40 -0.69 -8.16 -0.4 6.51e-15 LDL cholesterol;Cholesterol, total; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02196227 chr4:89080292 ABCG2 0.38 6.05 0.31 3.76e-9 Cognitive function; LIHC cis rs798554 0.660 rs798480 chr7:2805597 G/T cg13628971 chr7:2884303 GNA12 0.4 6.28 0.32 1.03e-9 Height; LIHC cis rs12477438 0.520 rs4588238 chr2:99749350 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.23 0.61 1.96e-36 Chronic sinus infection; LIHC cis rs6435862 0.500 rs6756902 chr2:215672827 C/T cg04004882 chr2:215674386 BARD1 -0.58 -8.74 -0.43 1.06e-16 Neuroblastoma (high-risk); LIHC cis rs3736485 0.966 rs4775961 chr15:51892959 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.25 -0.32 1.21e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs611744 0.967 rs666821 chr8:109204313 T/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs11098499 0.575 rs9996586 chr4:120326942 A/G cg09307838 chr4:120376055 NA 0.48 7.23 0.36 3.25e-12 Corneal astigmatism; LIHC cis rs6502050 0.842 rs7211808 chr17:80071244 T/C cg11859384 chr17:80120422 CCDC57 0.44 6.1 0.31 2.94e-9 Life satisfaction; LIHC cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg08280861 chr8:58055591 NA 0.54 6.28 0.32 1.05e-9 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg16606324 chr3:10149918 C3orf24 0.52 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs769267 1.000 rs2074090 chr19:19449686 G/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.27 -0.32 1.11e-9 Tonsillectomy; LIHC cis rs7408868 0.764 rs45504393 chr19:15277010 A/G cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.68e-8 Pulse pressure; LIHC cis rs35306767 0.714 rs17293608 chr10:1056252 C/T cg26597838 chr10:835615 NA 0.85 8.4 0.41 1.24e-15 Eosinophil percentage of granulocytes; LIHC cis rs12586317 0.620 rs2295104 chr14:35579927 A/G cg05294307 chr14:35346193 BAZ1A 0.5 7.39 0.37 1.15e-12 Psoriasis; LIHC cis rs11864453 0.713 rs8051882 chr16:72142072 A/G cg16558253 chr16:72132732 DHX38 0.46 7.11 0.36 6.68e-12 Fibrinogen levels; LIHC cis rs10463316 0.817 rs3846713 chr5:150799739 C/T cg03212797 chr5:150827313 SLC36A1 -0.46 -7.04 -0.36 1.05e-11 Metabolite levels (Pyroglutamine); LIHC cis rs3770081 1.000 rs6759489 chr2:86176032 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -8.7 -0.43 1.41e-16 Facial emotion recognition (sad faces); LIHC cis rs10744422 0.925 rs2880678 chr12:123317099 C/T cg25930673 chr12:123319894 HIP1R -0.84 -10.82 -0.51 1.13e-23 Schizophrenia; LIHC cis rs9611565 0.921 rs5758297 chr22:41720697 A/G cg03806693 chr22:41940476 POLR3H -0.44 -5.79 -0.3 1.63e-8 Vitiligo; LIHC cis rs17428076 0.556 rs12692976 chr2:172684403 G/T cg13550731 chr2:172543902 DYNC1I2 -0.48 -7.96 -0.4 2.53e-14 Myopia; LIHC cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg18404041 chr3:52824283 ITIH1 -0.56 -8.93 -0.44 2.58e-17 Bipolar disorder; LIHC cis rs9303401 0.612 rs2526370 chr17:56487636 G/C cg05425664 chr17:57184151 TRIM37 -0.48 -7.03 -0.36 1.12e-11 Cognitive test performance; LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg08677398 chr8:58056175 NA 0.41 6.32 0.32 8.32e-10 Developmental language disorder (linguistic errors); LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg26348180 chr3:193852754 HES1 -0.45 -6.3 -0.32 9.1e-10 Triglycerides; LIHC cis rs6964587 0.597 rs975707 chr7:91874527 C/G cg17063962 chr7:91808500 NA 0.63 10.05 0.48 5.56e-21 Breast cancer; LIHC cis rs7223966 0.921 rs11655493 chr17:61733052 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.55 6.42 0.33 4.58e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs769267 0.859 rs2916076 chr19:19545990 T/C cg03709012 chr19:19516395 GATAD2A 1.03 18.46 0.71 2.67e-53 Tonsillectomy; LIHC cis rs10256972 0.684 rs2363279 chr7:1096143 A/G cg23978390 chr7:1156363 C7orf50 0.53 7.72 0.39 1.32e-13 Longevity;Endometriosis; LIHC trans rs17515225 0.581 rs4423546 chr2:141543563 A/G cg22008625 chr8:10588386 SOX7 0.39 6.04 0.31 3.91e-9 Motion sickness; LIHC cis rs3793683 0.858 rs1571145 chr10:134583672 C/G cg27297192 chr10:134578999 INPP5A -0.48 -7.41 -0.37 1.02e-12 Migraine; LIHC trans rs1005277 0.540 rs4934907 chr10:38015230 A/C cg17830980 chr10:43048298 ZNF37B -0.42 -8.12 -0.4 8.5e-15 Extrinsic epigenetic age acceleration; LIHC cis rs9916302 0.718 rs10445306 chr17:37591422 A/G cg07936489 chr17:37558343 FBXL20 -0.84 -13.48 -0.59 1.65e-33 Glomerular filtration rate (creatinine); LIHC cis rs2404602 0.583 rs4381566 chr15:76589262 A/G cg23625390 chr15:77176239 SCAPER 0.35 6.04 0.31 4.01e-9 Blood metabolite levels; LIHC cis rs17685 0.753 rs1806885 chr7:75785612 T/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg12311346 chr5:56204834 C5orf35 -0.5 -6.56 -0.33 1.96e-10 Initial pursuit acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21517261 chr7:38217791 STARD3NL 0.41 6.4 0.33 5.02e-10 Cognitive function; LIHC cis rs882732 0.576 rs2070777 chr14:95034342 T/A cg14866387 chr14:95027382 SERPINA4 -0.39 -6.46 -0.33 3.67e-10 Blood protein levels; LIHC cis rs2834188 1.000 rs2096464 chr21:34686049 G/T cg04842828 chr21:34696676 IFNAR1 -0.45 -6.0 -0.31 5.11e-9 Narcolepsy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00379080 chr12:15942595 EPS8 0.41 6.1 0.31 2.95e-9 Lung function (FEV1/FVC); LIHC cis rs7727544 0.735 rs274558 chr5:131721174 A/G cg07395648 chr5:131743802 NA 0.33 6.9 0.35 2.57e-11 Blood metabolite levels; LIHC cis rs4919694 0.901 rs12264456 chr10:104830634 C/T cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs798554 1.000 rs798560 chr7:2758309 A/G cg04166393 chr7:2884313 GNA12 0.42 5.73 0.3 2.18e-8 Height; LIHC cis rs1801251 0.685 rs1515961 chr2:233623763 C/A cg25237894 chr2:233734115 C2orf82 0.4 7.65 0.38 2.03e-13 Coronary artery disease; LIHC cis rs4908760 0.613 rs2401189 chr1:8818600 G/A cg20416874 chr1:8611966 RERE -0.58 -10.45 -0.49 2.26e-22 Vitiligo; LIHC trans rs66573146 0.831 rs6851488 chr4:6987412 C/T cg07817883 chr1:32538562 TMEM39B 1.04 9.01 0.44 1.5e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs2075371 0.611 rs12531769 chr7:134016899 C/G cg20476274 chr7:133979776 SLC35B4 0.48 6.54 0.33 2.31e-10 Mean platelet volume; LIHC cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg23262073 chr20:60523788 NA -0.3 -6.31 -0.32 8.75e-10 Body mass index; LIHC cis rs7408868 0.908 rs10416777 chr19:15276923 C/T cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.68e-8 Pulse pressure; LIHC cis rs8017423 0.935 rs11159960 chr14:90740012 C/T cg04374321 chr14:90722782 PSMC1 -0.78 -14.73 -0.62 2.22e-38 Mortality in heart failure; LIHC cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg20607798 chr8:58055168 NA 0.65 7.93 0.39 3.16e-14 Developmental language disorder (linguistic errors); LIHC cis rs6456156 0.586 rs7746628 chr6:167483235 A/G cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.07e-9 Primary biliary cholangitis; LIHC trans rs11148252 0.740 rs9536052 chr13:52960709 C/G cg18335740 chr13:41363409 SLC25A15 -0.35 -6.13 -0.31 2.45e-9 Lewy body disease; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs8067354 0.872 rs1292060 chr17:57913849 A/G cg02344993 chr17:57696989 CLTC 0.57 9.1 0.44 7.53e-18 Hemoglobin concentration; LIHC cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg00149659 chr3:10157352 C3orf10 0.61 6.66 0.34 1.11e-10 Alzheimer's disease; LIHC trans rs1814175 0.616 rs1722020 chr11:49904189 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs6546550 0.835 rs3755389 chr2:70119469 T/C cg02498382 chr2:70120550 SNRNP27 -0.45 -7.69 -0.38 1.5700000000000001e-13 Prevalent atrial fibrillation; LIHC cis rs919433 0.854 rs787994 chr2:198223121 T/C cg03934865 chr2:198174659 NA 0.53 8.26 0.41 3.23e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11792861 0.781 rs838835 chr9:111758590 A/G cg05043794 chr9:111880884 C9orf5 0.29 6.69 0.34 9.27e-11 Menarche (age at onset); LIHC cis rs1577917 0.958 rs9647601 chr6:86449827 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.46 -8.62 -0.42 2.6e-16 Response to antipsychotic treatment; LIHC cis rs6964587 0.934 rs6465344 chr7:91640273 G/A cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs244293 0.965 rs12453615 chr17:53177509 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.54 0.38 4.36e-13 Menarche (age at onset); LIHC cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg06238570 chr21:40685208 BRWD1 -0.37 -6.05 -0.31 3.84e-9 Menarche (age at onset); LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg26144567 chr1:29446085 EPB41;TMEM200B 0.55 6.28 0.32 1.05e-9 Mean platelet volume; LIHC cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg06238570 chr21:40685208 BRWD1 0.61 7.28 0.37 2.36e-12 Cognitive function; LIHC cis rs2832191 0.646 rs2832210 chr21:30508723 T/G cg24692254 chr21:30365293 RNF160 -0.41 -6.45 -0.33 3.79e-10 Dental caries; LIHC cis rs17253792 0.822 rs77033617 chr14:56129746 T/A cg01858014 chr14:56050164 KTN1 -0.71 -7.22 -0.36 3.38e-12 Putamen volume; LIHC cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg11062466 chr8:58055876 NA 0.4 5.84 0.3 1.22e-8 Developmental language disorder (linguistic errors); LIHC cis rs6121246 0.697 rs6088864 chr20:30228157 G/A cg13852791 chr20:30311386 BCL2L1 0.78 7.93 0.39 3.18e-14 Mean corpuscular hemoglobin; LIHC cis rs7944735 0.508 rs1474056 chr11:47632707 G/A cg20307385 chr11:47447363 PSMC3 -0.54 -6.07 -0.31 3.4e-9 Intraocular pressure; LIHC cis rs11711311 0.955 rs12636240 chr3:113391282 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.35 -5.86 -0.3 1.06e-8 IgG glycosylation; LIHC trans rs7613875 0.641 rs6793528 chr3:50100188 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.58 -0.34 1.82e-10 Body mass index; LIHC cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.59 -6.19 -0.32 1.74e-9 Lung function (FEV1/FVC); LIHC cis rs4423214 0.559 rs10898201 chr11:71201527 C/A cg05163923 chr11:71159392 DHCR7 -0.57 -7.09 -0.36 7.78e-12 Vitamin D levels; LIHC trans rs11165623 0.585 rs55896436 chr1:96994162 G/A cg10631902 chr5:14652156 NA -0.3 -6.87 -0.35 3.02e-11 Hip circumference;Waist circumference; LIHC cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs9916302 0.904 rs7223438 chr17:37521355 T/C cg07936489 chr17:37558343 FBXL20 0.82 12.99 0.57 1.28e-31 Glomerular filtration rate (creatinine); LIHC trans rs7246657 0.882 rs6508719 chr19:37877419 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.6 0.34 1.61e-10 Coronary artery calcification; LIHC cis rs11671005 0.611 rs36090113 chr19:58912384 G/C cg25952890 chr19:58913133 NA 0.68 6.89 0.35 2.77e-11 Mean platelet volume; LIHC cis rs5753037 0.564 rs131298 chr22:30180001 C/T cg01021169 chr22:30184971 ASCC2 0.44 8.81 0.43 6.3e-17 Type 1 diabetes; LIHC trans rs6952808 0.862 rs4721167 chr7:1933224 C/T cg04565464 chr8:145669602 NFKBIL2 0.39 6.17 0.32 1.95e-9 Bipolar disorder and schizophrenia; LIHC cis rs11758351 0.929 rs6906367 chr6:26187125 C/T cg11342453 chr6:26196699 NA 0.47 5.74 0.3 2.04e-8 Gout;Renal underexcretion gout; LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg10360139 chr7:1886902 MAD1L1 -0.41 -6.3 -0.32 9.03e-10 Bipolar disorder and schizophrenia; LIHC cis rs7412746 0.586 rs2864882 chr1:150883037 C/T cg18016565 chr1:150552671 MCL1 0.5 9.64 0.46 1.3e-19 Melanoma; LIHC cis rs7584330 0.554 rs10183995 chr2:238433307 G/A cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.39e-9 Prostate cancer; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg26338869 chr17:61819248 STRADA -0.6 -8.78 -0.43 7.93e-17 Prudent dietary pattern; LIHC cis rs4561483 0.801 rs40311 chr16:11963190 C/G cg08843971 chr16:11963173 GSPT1 0.44 8.72 0.43 1.26e-16 Testicular germ cell tumor; LIHC trans rs2243480 0.901 rs2456483 chr7:65461575 T/C cg10756647 chr7:56101905 PSPH 1.11 13.6 0.59 5.63e-34 Diabetic kidney disease; LIHC cis rs6728642 0.572 rs13387563 chr2:97600916 C/A cg26665480 chr2:98280029 ACTR1B -0.53 -6.64 -0.34 1.26e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs7224685 0.569 rs965515 chr17:4038149 G/A cg11204139 chr17:3907470 NA 0.6 6.9 0.35 2.54e-11 Type 2 diabetes; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05590616 chr11:59522917 STX3 0.43 6.37 0.33 6.07e-10 Lung function (FEV1/FVC); LIHC cis rs1559088 0.847 rs8100392 chr19:33605933 T/C cg17764715 chr19:33622953 WDR88 0.45 6.5 0.33 2.78e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs4906332 1.000 rs17617935 chr14:103952886 A/T cg17675199 chr6:35436792 RPL10A 0.35 6.89 0.35 2.66e-11 Coronary artery disease; LIHC cis rs6963495 0.818 rs73192115 chr7:105169605 T/A cg19920283 chr7:105172520 RINT1 0.69 6.39 0.33 5.38e-10 Bipolar disorder (body mass index interaction); LIHC cis rs6840360 0.530 rs12645029 chr4:152650032 T/C cg22705602 chr4:152727874 NA -0.4 -7.42 -0.37 9.39e-13 Intelligence (multi-trait analysis); LIHC cis rs10791323 0.604 rs2853115 chr11:133707908 C/T cg06766960 chr11:133703094 NA 0.66 11.19 0.52 5.6e-25 Childhood ear infection; LIHC cis rs7959452 0.535 rs10784771 chr12:69621264 A/G cg22834771 chr12:69754056 YEATS4 -0.44 -7.55 -0.38 4.06e-13 Blood protein levels; LIHC cis rs2197308 0.606 rs12314897 chr12:38392293 C/T cg26384229 chr12:38710491 ALG10B -0.46 -5.99 -0.31 5.31e-9 Morning vs. evening chronotype; LIHC cis rs9818758 0.607 rs61729488 chr3:49067904 T/C cg07636037 chr3:49044803 WDR6 -0.84 -7.08 -0.36 8.28e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs1005277 0.579 rs1780146 chr10:38517874 C/A cg17830980 chr10:43048298 ZNF37B -0.52 -10.07 -0.48 4.6e-21 Extrinsic epigenetic age acceleration; LIHC cis rs7520050 0.751 rs592214 chr1:46024505 G/A cg24296786 chr1:45957014 TESK2 0.41 5.79 0.3 1.61e-8 Red blood cell count;Reticulocyte count; LIHC cis rs6121246 0.529 rs6088814 chr20:30218172 C/T cg13852791 chr20:30311386 BCL2L1 0.78 6.77 0.34 5.69e-11 Mean corpuscular hemoglobin; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07853919 chr18:77711868 PQLC1 -0.38 -6.32 -0.32 8.28e-10 Pancreatic cancer; LIHC trans rs3749237 1.000 rs11717256 chr3:49868520 C/T cg21659725 chr3:3221576 CRBN 0.78 12.12 0.55 2.34e-28 Resting heart rate; LIHC cis rs7937890 0.900 rs7118682 chr11:14274550 T/G cg02886208 chr11:14281011 SPON1 0.61 9.07 0.44 9.36e-18 Mitochondrial DNA levels; LIHC cis rs116095464 0.764 rs10069197 chr5:230822 G/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs9929218 0.906 rs9932679 chr16:68751904 A/G cg01231543 chr16:68741748 NA 0.38 5.77 0.3 1.8e-8 Colorectal cancer; LIHC cis rs9733 0.565 rs7524620 chr1:150616699 C/T cg13175981 chr1:150552382 MCL1 0.41 5.79 0.3 1.56e-8 Tonsillectomy; LIHC trans rs9951602 0.512 rs8085719 chr18:76649111 A/G cg02800362 chr5:177631904 HNRNPAB 0.67 10.64 0.5 4.9e-23 Obesity-related traits; LIHC cis rs6920965 0.507 rs9385388 chr6:126215296 C/T cg05901451 chr6:126070800 HEY2 -0.36 -6.23 -0.32 1.37e-9 High light scatter reticulocyte count; LIHC trans rs5756813 0.754 rs13057133 chr22:38179473 C/T cg19894588 chr14:64061835 NA -0.62 -8.58 -0.42 3.38e-16 Optic cup area;Vertical cup-disc ratio; LIHC cis rs6570726 0.599 rs455001 chr6:145854450 A/T cg13319975 chr6:146136371 FBXO30 -0.55 -8.74 -0.43 1.05e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg24693881 chr1:107596107 NA 0.55 9.61 0.46 1.59e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6570726 0.791 rs13202312 chr6:145913093 T/G cg23711669 chr6:146136114 FBXO30 0.73 12.2 0.55 1.17e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg20887711 chr4:1340912 KIAA1530 0.49 7.67 0.38 1.86e-13 Obesity-related traits; LIHC cis rs875971 0.545 rs316323 chr7:65610989 C/T cg11764359 chr7:65958608 NA -0.52 -7.1 -0.36 7.24e-12 Aortic root size; LIHC cis rs7914558 1.000 rs4917380 chr10:104775335 C/G cg04362960 chr10:104952993 NT5C2 0.38 5.75 0.3 1.98e-8 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs8062405 1.000 rs8055138 chr16:28891465 C/T cg07451762 chr16:28383216 NA 0.32 5.96 0.31 6.31e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs17685 0.712 rs59659102 chr7:75710114 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.21 -0.32 1.52e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8062405 0.755 rs7186573 chr16:28587389 T/C cg07382826 chr16:28625726 SULT1A1 0.49 7.7 0.38 1.52e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8078723 1.000 rs4794824 chr17:38179290 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.58 -9.39 -0.45 8.73e-19 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg09367891 chr1:107599246 PRMT6 0.71 11.88 0.54 1.68e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9916302 0.808 rs6503515 chr17:37606433 G/T cg07936489 chr17:37558343 FBXL20 -0.85 -13.69 -0.6 2.49e-34 Glomerular filtration rate (creatinine); LIHC cis rs9916302 0.706 rs594794 chr17:37453485 T/C cg07936489 chr17:37558343 FBXL20 0.84 12.3 0.55 4.68e-29 Glomerular filtration rate (creatinine); LIHC cis rs17854409 1.000 rs66956644 chr20:61484499 T/C cg05147244 chr20:61493195 TCFL5 1.22 11.03 0.51 2.02e-24 Obesity-related traits; LIHC cis rs9715521 0.775 rs67846233 chr4:59848576 G/A cg11281224 chr4:60001000 NA -0.31 -5.73 -0.3 2.24e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs10170846 0.800 rs10194743 chr2:223518151 A/G cg25565276 chr2:223520875 FARSB 0.65 9.73 0.47 6.74e-20 Schizophrenia (inflammation and infection response interaction); LIHC trans rs56011263 0.687 rs4690292 chr4:703712 A/G cg12575136 chr18:32820987 ZNF397 0.47 6.91 0.35 2.44e-11 White blood cell count; LIHC cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.26e-9 Menopause (age at onset); LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs6912958 0.559 rs499373 chr6:88042062 A/T cg08069147 chr6:88032118 GJB7;C6orf162 0.61 11.36 0.52 1.34e-25 Monocyte percentage of white cells; LIHC cis rs4975709 1.000 rs4975709 chr5:1877280 A/C cg15595755 chr5:1867978 NA 0.32 6.12 0.31 2.5e-9 Cardiovascular disease risk factors; LIHC cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg00106254 chr7:1943704 MAD1L1 -0.4 -6.52 -0.33 2.56e-10 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg00280220 chr17:61926910 NA 0.42 6.61 0.34 1.51e-10 Prudent dietary pattern; LIHC cis rs2271400 1.000 rs2271400 chr8:56791244 C/T cg08894788 chr8:56792171 LYN -0.39 -5.75 -0.3 2e-8 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Myeloid white cell count;Neutrophil count;Granulocyte count; LIHC cis rs4888262 0.526 rs13330282 chr16:74572373 C/T cg01733217 chr16:74700730 RFWD3 0.8 15.73 0.65 2.42e-42 Testicular germ cell tumor; LIHC cis rs9814567 0.727 rs7641798 chr3:134345719 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.55 -8.87 -0.43 4.23e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs250677 0.524 rs417413 chr5:148452726 T/C cg18129178 chr5:148520854 ABLIM3 -0.37 -6.15 -0.32 2.13e-9 Breast cancer; LIHC cis rs10870270 1.000 rs11146338 chr10:133770291 C/G cg17892150 chr10:133769511 PPP2R2D -0.68 -12.84 -0.57 4.5e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs2727020 0.658 rs1851992 chr11:49438110 C/T cg03929089 chr4:120376271 NA -0.85 -16.46 -0.66 3.08e-45 Coronary artery disease; LIHC cis rs2274273 0.673 rs2209808 chr14:55807695 A/T cg01864836 chr14:55583639 NA -0.38 -6.67 -0.34 1.02e-10 Protein biomarker; LIHC cis rs11098499 0.874 rs10022508 chr4:120115228 A/G cg09307838 chr4:120376055 NA 0.52 7.74 0.39 1.16e-13 Corneal astigmatism; LIHC cis rs597539 0.652 rs611046 chr11:68631704 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.73 10.61 0.5 6.46e-23 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs3784262 0.935 rs4646563 chr15:58353335 T/C cg12031962 chr15:58353849 ALDH1A2 -0.35 -6.86 -0.35 3.28e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6570726 0.935 rs369458 chr6:145812809 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.87 0.47 2.17e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs17106184 1.000 rs72902776 chr1:51269954 G/A cg07174182 chr1:51127561 FAF1 -0.65 -7.06 -0.36 9.43e-12 Type 2 diabetes; LIHC cis rs9467773 1.000 rs6932156 chr6:26571506 T/G cg09904177 chr6:26538194 HMGN4 0.66 13.67 0.59 3.1e-34 Intelligence (multi-trait analysis); LIHC cis rs13256369 0.802 rs11249885 chr8:8562008 C/T cg00074818 chr8:8560427 CLDN23 0.38 6.28 0.32 1.03e-9 Obesity-related traits; LIHC cis rs2197308 0.765 rs68029712 chr12:37906585 T/G cg13010199 chr12:38710504 ALG10B 0.5 5.78 0.3 1.68e-8 Morning vs. evening chronotype; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg02083259 chr16:57220135 RSPRY1;FAM192A -0.44 -6.44 -0.33 4.01e-10 Body mass index; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg22387756 chr11:1495050 HCCA2 0.44 6.24 0.32 1.31e-9 Longevity; LIHC cis rs55882075 0.722 rs10903245 chr5:179133608 T/C cg14593053 chr5:179126677 CANX 0.43 7.8 0.39 7.38e-14 Monocyte percentage of white cells; LIHC cis rs2645694 0.533 rs2645681 chr4:77820949 G/A cg03477792 chr4:77819574 ANKRD56 0.61 8.86 0.43 4.39e-17 Emphysema distribution in smoking; LIHC cis rs7662987 0.517 rs4235436 chr4:100039620 G/A cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs9616064 0.889 rs7284276 chr22:46996137 G/C cg05621596 chr22:47072043 GRAMD4 -0.51 -7.2 -0.36 3.81e-12 Urate levels in obese individuals; LIHC cis rs7107174 0.681 rs4340079 chr11:78007920 C/T cg02023728 chr11:77925099 USP35 0.45 8.78 0.43 8.03e-17 Testicular germ cell tumor; LIHC cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg11644478 chr21:40555479 PSMG1 0.8 10.21 0.48 1.49e-21 Cognitive function; LIHC cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.08e-11 Alzheimer's disease; LIHC cis rs9291683 0.588 rs6857693 chr4:10018435 G/A cg11266682 chr4:10021025 SLC2A9 0.33 7.15 0.36 5.29e-12 Bone mineral density; LIHC cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg12311346 chr5:56204834 C5orf35 -0.5 -6.57 -0.33 1.91e-10 Initial pursuit acceleration; LIHC cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg26338869 chr17:61819248 STRADA -0.59 -8.46 -0.42 7.9e-16 Prudent dietary pattern; LIHC cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg26566898 chr11:117069891 TAGLN 0.46 7.23 0.36 3.23e-12 Blood protein levels; LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg17178900 chr1:205818956 PM20D1 0.66 9.9 0.47 1.77e-20 Menarche (age at onset); LIHC cis rs9916302 0.904 rs4794814 chr17:37696852 G/A cg00129232 chr17:37814104 STARD3 -0.42 -6.72 -0.34 7.42e-11 Glomerular filtration rate (creatinine); LIHC cis rs12586317 0.883 rs4982254 chr14:35755737 C/T cg16230307 chr14:35515116 FAM177A1 0.49 7.43 0.37 8.49e-13 Psoriasis; LIHC cis rs7659604 0.676 rs7691955 chr4:122700462 A/T cg20573242 chr4:122745356 CCNA2 0.52 7.54 0.38 4.2e-13 Type 2 diabetes; LIHC cis rs2075371 0.734 rs13225086 chr7:134011411 C/T cg20476274 chr7:133979776 SLC35B4 0.59 7.96 0.4 2.57e-14 Mean platelet volume; LIHC trans rs11039798 0.541 rs12283728 chr11:48796407 G/A cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs2760061 0.819 rs1745416 chr1:228204497 G/A cg02753203 chr1:228287806 NA 0.49 8.07 0.4 1.21e-14 Diastolic blood pressure; LIHC cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg21644426 chr2:191273491 MFSD6 0.56 7.64 0.38 2.19e-13 Pulse pressure; LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg03721293 chr16:90014378 DEF8 0.36 6.31 0.32 8.77e-10 Skin colour saturation; LIHC cis rs12893668 0.572 rs2273175 chr14:104160141 T/C cg24130564 chr14:104152367 KLC1 -0.57 -10.03 -0.48 6.17e-21 Reticulocyte count; LIHC cis rs240764 0.658 rs10872634 chr6:101199579 C/T cg09795085 chr6:101329169 ASCC3 -0.54 -7.6 -0.38 2.95e-13 Neuroticism; LIHC trans rs3780486 0.505 rs959749 chr9:33147858 T/C cg04842962 chr6:43655489 MRPS18A 0.8 15.39 0.64 5.49e-41 IgG glycosylation; LIHC cis rs4671400 0.571 rs62152275 chr2:61502238 C/A cg14146966 chr2:61757674 XPO1 -0.37 -5.86 -0.3 1.1e-8 3-hydroxypropylmercapturic acid levels in smokers; LIHC cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg17747265 chr1:1875780 NA 0.56 10.93 0.51 4.8e-24 Body mass index; LIHC cis rs60871478 1.000 rs4719314 chr7:822523 A/G cg05535760 chr7:792225 HEATR2 0.79 10.83 0.51 1.04e-23 Cerebrospinal P-tau181p levels; LIHC cis rs6545883 0.931 rs7557230 chr2:61736652 A/T cg14146966 chr2:61757674 XPO1 0.48 8.37 0.41 1.48e-15 Tuberculosis; LIHC cis rs2228479 0.717 rs34027607 chr16:89808939 T/C cg06558623 chr16:89946397 TCF25 0.82 11.52 0.53 3.71e-26 Skin colour saturation; LIHC cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -12.11 -0.55 2.44e-28 Alzheimer's disease; LIHC cis rs17685 0.753 rs4732595 chr7:75755139 A/G cg04610667 chr7:75704037 NA -0.33 -5.98 -0.31 5.5e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8062405 1.000 rs7498555 chr16:28893571 T/C cg07451762 chr16:28383216 NA 0.33 6.14 0.32 2.27e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7223966 1.000 rs11870797 chr17:61804622 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.96 0.35 1.72e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7674212 0.541 rs17217473 chr4:104114742 A/C cg16532752 chr4:104119610 CENPE -0.42 -6.48 -0.33 3.29e-10 Type 2 diabetes; LIHC cis rs7712401 0.755 rs6595407 chr5:122100398 C/T cg18764291 chr5:122110994 SNX2 0.35 6.02 0.31 4.38e-9 Mean platelet volume; LIHC cis rs8030605 0.516 rs12440142 chr15:56537518 G/A cg00626843 chr15:56536071 RFX7 0.46 6.02 0.31 4.49e-9 Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg15691649 chr6:25882328 NA -0.6 -8.02 -0.4 1.68e-14 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.555 rs56228141 chr12:38518652 T/G cg26384229 chr12:38710491 ALG10B 0.7 9.86 0.47 2.39e-20 Drug-induced liver injury (flucloxacillin); LIHC trans rs1814175 0.817 rs1851860 chr11:49861310 A/C cg03929089 chr4:120376271 NA -0.89 -18.3 -0.7 1.2e-52 Height; LIHC cis rs2834188 0.889 rs8134026 chr21:34671098 T/A cg14352951 chr21:34696688 IFNAR1 0.52 7.06 0.36 9.18e-12 Narcolepsy; LIHC trans rs8002861 0.935 rs7318147 chr13:44445153 C/G cg23520726 chr13:45563622 NUFIP1;KIAA1704 0.49 6.56 0.33 2.02e-10 Leprosy; LIHC cis rs12682352 0.602 rs11783966 chr8:8665147 A/G cg06636001 chr8:8085503 FLJ10661 -0.42 -6.69 -0.34 9.1e-11 Neuroticism; LIHC cis rs7903847 0.642 rs11189172 chr10:99135215 T/C cg20016023 chr10:99160130 RRP12 -0.4 -6.41 -0.33 4.86e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1577917 0.655 rs9444352 chr6:86257535 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.56 0.42 3.91e-16 Response to antipsychotic treatment; LIHC trans rs10411161 0.580 rs12151287 chr19:52381495 C/T cg22319618 chr22:45562946 NUP50 -0.5 -7.41 -0.37 1.03e-12 Breast cancer; LIHC cis rs1577917 1.000 rs12204365 chr6:86700532 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.38 -0.33 5.85e-10 Response to antipsychotic treatment; LIHC cis rs3008870 0.785 rs10889651 chr1:67463513 A/T cg08660285 chr1:67390436 MIER1;WDR78 -0.64 -10.88 -0.51 7.3e-24 Lymphocyte percentage of white cells; LIHC cis rs1816752 0.870 rs7981480 chr13:25015104 A/G cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC cis rs763121 0.925 rs9835 chr22:39130971 A/G cg06544989 chr22:39130855 UNC84B 0.37 6.14 0.32 2.27e-9 Menopause (age at onset); LIHC cis rs11030122 0.673 rs10835508 chr11:4045360 A/T cg18678763 chr11:4115507 RRM1 -0.53 -8.02 -0.4 1.74e-14 Mean platelet volume;Platelet distribution width; LIHC cis rs12477438 0.765 rs1115756 chr2:99659845 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs4713118 0.869 rs9283882 chr6:27715258 A/C cg20933634 chr6:27740509 NA 0.47 6.19 0.32 1.69e-9 Parkinson's disease; LIHC cis rs4660261 0.526 rs3094954 chr1:44320919 C/T cg12908607 chr1:44402522 ARTN -0.46 -7.68 -0.38 1.68e-13 Intelligence (multi-trait analysis); LIHC cis rs921968 0.643 rs3932856 chr2:219320207 C/A cg02176678 chr2:219576539 TTLL4 0.37 5.72 0.3 2.36e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs2075371 1.000 rs2075371 chr7:133984127 A/G cg11752832 chr7:134001865 SLC35B4 0.52 7.83 0.39 6.14e-14 Mean platelet volume; LIHC cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg25204440 chr1:209979598 IRF6 0.47 7.12 0.36 6.35e-12 Cleft lip with or without cleft palate; LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg12034118 chr1:209979487 IRF6 0.37 5.71 0.3 2.44e-8 Cleft lip with or without cleft palate; LIHC cis rs600806 0.850 rs7518013 chr1:109944078 C/T cg16275483 chr1:110013120 SYPL2 0.48 6.02 0.31 4.56e-9 Intelligence (multi-trait analysis); LIHC cis rs3736757 0.603 rs12137438 chr1:184650034 A/C cg07817967 chr1:184721222 EDEM3 0.36 5.8 0.3 1.54e-8 Obesity-related traits; LIHC cis rs2228479 0.850 rs11644213 chr16:89837367 C/T cg19635926 chr16:89946313 TCF25 -0.48 -5.98 -0.31 5.72e-9 Skin colour saturation; LIHC cis rs12477438 0.559 rs6733285 chr2:99725575 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs10979 1.000 rs9403504 chr6:143885430 G/A cg25407410 chr6:143891975 LOC285740 -0.37 -5.95 -0.31 6.57e-9 Hypospadias; LIHC cis rs7635838 0.596 rs347599 chr3:11258191 C/T cg00170343 chr3:11313890 ATG7 -0.53 -8.54 -0.42 4.38e-16 HDL cholesterol; LIHC trans rs7618501 0.574 rs6765484 chr3:50041313 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.56 -9.13 -0.44 6.08e-18 Intelligence (multi-trait analysis); LIHC trans rs10411161 0.702 rs11878583 chr19:52388546 C/T cg22319618 chr22:45562946 NUP50 0.58 8.17 0.4 6.02e-15 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15604682 chr7:102105781 ALKBH4;LRWD1 0.51 6.81 0.35 4.29e-11 Lung function (FEV1/FVC); LIHC cis rs3814231 0.589 rs12357967 chr10:115469710 G/A cg24846397 chr10:115438155 CASP7 -0.42 -6.98 -0.35 1.53e-11 Vitiligo; LIHC cis rs9918079 0.542 rs6414765 chr4:15626493 G/A cg16509355 chr4:15471240 CC2D2A -0.44 -6.71 -0.34 7.97e-11 Obesity-related traits; LIHC cis rs10911232 0.507 rs4651137 chr1:182994300 T/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs6442522 1.000 rs6762167 chr3:15445037 A/T cg16303742 chr3:15540471 COLQ -0.41 -6.89 -0.35 2.69e-11 Uric acid levels; LIHC cis rs10131894 0.611 rs174995 chr14:75434183 T/C cg08847533 chr14:75593920 NEK9 -0.84 -16.17 -0.66 4.41e-44 Coronary artery disease; LIHC cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg04546413 chr19:29218101 NA 0.56 10.17 0.48 2.16e-21 Methadone dose in opioid dependence; LIHC cis rs11971779 0.590 rs59602547 chr7:139117023 G/A cg07862535 chr7:139043722 LUC7L2 0.6 10.39 0.49 3.67e-22 Diisocyanate-induced asthma; LIHC cis rs10744422 1.000 rs937766 chr12:123331094 G/T cg18912006 chr12:123335444 HIP1R -0.63 -7.64 -0.38 2.14e-13 Schizophrenia; LIHC cis rs12220238 1.000 rs10824076 chr10:75886956 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.99 0.35 1.43e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs12928939 0.815 rs12446005 chr16:71655035 G/A cg03805757 chr16:71968109 PKD1L3 -0.55 -6.34 -0.32 7.13e-10 Post bronchodilator FEV1; LIHC trans rs783540 0.934 rs783530 chr15:83266549 G/C cg18393722 chr15:85113863 UBE2QP1 -0.39 -6.66 -0.34 1.07e-10 Schizophrenia; LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.59 -8.49 -0.42 6.43e-16 Lymphocyte counts; LIHC cis rs3824867 0.676 rs7104366 chr11:47462115 G/A cg20307385 chr11:47447363 PSMC3 0.57 7.73 0.39 1.19e-13 Mean corpuscular hemoglobin; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11872478 chr2:96196596 NA 0.39 6.67 0.34 1.01e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs8077889 0.672 rs2106764 chr17:41852717 T/A cg26893861 chr17:41843967 DUSP3 1.05 18.46 0.71 2.87e-53 Triglycerides; LIHC cis rs1552244 0.882 rs13099507 chr3:10031603 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 10.29 0.49 8.41e-22 Alzheimer's disease; LIHC cis rs10716631 1 rs10716631 chr2:219138170 T/G cg00012203 chr2:219082015 ARPC2 0.87 14.15 0.61 4.36e-36 High light scatter reticulocyte percentage of red cells;Plateletcrit; LIHC cis rs1552244 0.572 rs3894322 chr3:10168965 G/A cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs9372498 0.505 rs3734345 chr6:118637042 T/C cg01339444 chr6:118972232 C6orf204 0.74 6.07 0.31 3.38e-9 Diastolic blood pressure; LIHC cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg16680214 chr1:154839983 KCNN3 -0.35 -5.95 -0.31 6.64e-9 Prostate cancer; LIHC cis rs611744 0.870 rs640068 chr8:109158002 A/G cg21045802 chr8:109455806 TTC35 0.5 8.8 0.43 6.75e-17 Dupuytren's disease; LIHC cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg07677032 chr17:61819896 STRADA 0.43 6.21 0.32 1.56e-9 Prudent dietary pattern; LIHC cis rs11233413 1.000 rs11233418 chr11:82728462 G/A cg24227371 chr11:82718527 RAB30 -0.32 -7.06 -0.36 9.36e-12 Economic and political preferences (feminism/equality); LIHC cis rs1865721 0.761 rs62089540 chr18:73218332 G/A cg26385618 chr18:73139727 C18orf62 -0.27 -7.14 -0.36 5.66e-12 Intelligence; LIHC cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg00656387 chr3:40428638 ENTPD3 0.43 7.21 0.36 3.63e-12 Renal cell carcinoma; LIHC cis rs2710642 0.564 rs7558681 chr2:62840987 G/A cg17519650 chr2:63277830 OTX1 0.43 6.72 0.34 7.67e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs3857067 0.806 rs2171384 chr4:95103545 G/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.58 -0.38 3.25e-13 QT interval; LIHC cis rs8017423 0.647 rs4904673 chr14:90817338 G/A cg04374321 chr14:90722782 PSMC1 -0.5 -7.22 -0.36 3.42e-12 Mortality in heart failure; LIHC cis rs4700695 0.841 rs417152 chr5:65316205 G/A cg21114390 chr5:65439923 SFRS12 0.45 5.87 0.3 1.05e-8 Facial morphology (factor 19); LIHC cis rs1538970 0.781 rs11211139 chr1:46015751 G/T cg05343316 chr1:45956843 TESK2 0.61 8.1 0.4 1.01e-14 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06713297 chr1:242011104 EXO1 0.52 7.38 0.37 1.19e-12 Pancreatic cancer; LIHC cis rs11690935 0.959 rs10174525 chr2:172635697 T/C cg13550731 chr2:172543902 DYNC1I2 -0.95 -18.99 -0.72 2.02e-55 Schizophrenia; LIHC cis rs9457247 1.000 rs386548 chr6:167385533 A/T cg07741184 chr6:167504864 NA -0.24 -5.71 -0.3 2.4e-8 Crohn's disease; LIHC cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.3 0.45 1.74e-18 Bipolar disorder; LIHC cis rs7412746 0.611 rs11204748 chr1:150927369 G/T cg18016565 chr1:150552671 MCL1 0.49 9.33 0.45 1.38e-18 Melanoma; LIHC cis rs7953508 0.711 rs11107117 chr12:93979419 T/C cg18151635 chr12:93972918 NA -0.49 -7.54 -0.38 4.29e-13 Pubertal anthropometrics; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03150409 chr4:1892317 WHSC1 0.4 6.15 0.32 2.13e-9 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10512748 chr1:28844557 SNHG3-RCC1;RCC1 0.46 6.17 0.32 1.96e-9 Pancreatic cancer; LIHC cis rs2933343 0.533 rs13086121 chr3:128704290 A/T cg25356066 chr3:128598488 ACAD9 0.45 6.09 0.31 3.09e-9 IgG glycosylation; LIHC cis rs868036 0.681 rs4776978 chr15:68108305 A/G cg24579218 chr15:68104479 NA -0.34 -5.8 -0.3 1.53e-8 Restless legs syndrome; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg16968413 chr4:39183824 WDR19 0.39 6.72 0.34 7.48e-11 Calcium levels; LIHC cis rs12586317 0.586 rs74243590 chr14:35513246 G/A cg16230307 chr14:35515116 FAM177A1 0.82 13.8 0.6 9.62e-35 Psoriasis; LIHC cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg21782813 chr7:2030301 MAD1L1 0.49 8.63 0.42 2.35e-16 Bipolar disorder and schizophrenia; LIHC trans rs877282 0.853 rs7079450 chr10:755932 T/A cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs986417 0.748 rs10150234 chr14:61031284 C/G cg27398547 chr14:60952738 C14orf39 -0.78 -8.87 -0.43 4.1e-17 Gut microbiota (bacterial taxa); LIHC cis rs888194 0.690 rs3782894 chr12:110026024 G/T cg05360138 chr12:110035743 NA 0.41 5.88 0.3 9.94e-9 Neuroticism; LIHC cis rs6840360 1.000 rs6535811 chr4:152598992 C/T cg22705602 chr4:152727874 NA -0.32 -6.74 -0.34 6.95e-11 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg23978390 chr7:1156363 C7orf50 0.52 7.91 0.39 3.61e-14 Longevity;Endometriosis; LIHC cis rs9393692 0.905 rs6908328 chr6:26292855 C/A cg00631329 chr6:26305371 NA -0.44 -7.38 -0.37 1.21e-12 Educational attainment; LIHC cis rs916888 0.821 rs199512 chr17:44857352 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.71 -6.85 -0.35 3.47e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC cis rs2531992 0.620 rs2041248 chr16:4032489 T/G cg05927578 chr16:4029543 ADCY9 0.52 7.04 0.36 1.07e-11 Waist circumference; LIHC cis rs62064224 0.702 rs735555 chr17:30817450 A/G cg25809561 chr17:30822961 MYO1D -0.56 -7.34 -0.37 1.56e-12 Schizophrenia; LIHC cis rs116248771 0.739 rs12639329 chr3:158347145 T/C cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.75e-10 diarrhoeal disease at age 2; LIHC cis rs365132 1.000 rs7718874 chr5:176358065 A/G cg16309518 chr5:176445507 NA -0.57 -11.25 -0.52 3.35e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs6762 0.748 rs1130663 chr11:837582 G/A cg07691484 chr11:842764 TSPAN4;POLR2L -0.75 -9.7 -0.46 7.99e-20 Mean platelet volume; LIHC trans rs11098499 0.909 rs79704848 chr4:120309351 T/A cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs5769765 0.865 rs9616369 chr22:50304591 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.23 -0.45 2.93e-18 Schizophrenia; LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg24101359 chr6:42928495 GNMT 0.43 5.85 0.3 1.16e-8 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs3783890 1.000 rs11621084 chr14:93764989 C/T cg02802420 chr16:69363236 PDF;COG8 0.32 6.28 0.32 1.01e-9 Body mass index; LIHC trans rs1814175 0.645 rs4411280 chr11:49962750 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC trans rs11039798 0.623 rs635632 chr11:48399532 T/C cg15704280 chr7:45808275 SEPT13 -0.57 -6.32 -0.32 8.05e-10 Axial length; LIHC cis rs8017423 0.935 rs11159959 chr14:90733656 C/T cg04374321 chr14:90722782 PSMC1 -0.77 -14.08 -0.61 7.54e-36 Mortality in heart failure; LIHC cis rs1055129 0.516 rs7218498 chr17:73931847 C/G cg14829360 chr17:73884958 NA -0.38 -6.41 -0.33 4.84e-10 White matter hyperintensity burden; LIHC cis rs600806 0.815 rs4970754 chr1:109969721 A/G cg16275483 chr1:110013120 SYPL2 -0.49 -6.04 -0.31 4.11e-9 Intelligence (multi-trait analysis); LIHC cis rs7959452 0.640 rs1598543 chr12:69688757 G/T cg22834771 chr12:69754056 YEATS4 -0.48 -8.08 -0.4 1.11e-14 Blood protein levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15083964 chr4:56212371 SRD5A3 -0.44 -6.41 -0.33 4.83e-10 Pancreatic cancer; LIHC cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg27572855 chr1:25598939 RHD -0.42 -9.35 -0.45 1.14e-18 Erythrocyte sedimentation rate; LIHC trans rs16973084 1 rs16973084 chr15:82016618 C/T cg05832051 chr19:54369469 MYADM 0.46 6.17 0.32 1.88e-9 Depressive symptoms; LIHC cis rs12908161 1.000 rs62019464 chr15:85294469 T/A cg12863693 chr15:85201151 NMB 0.44 6.31 0.32 8.81e-10 Schizophrenia; LIHC cis rs56235845 0.694 rs6860069 chr5:176755841 C/T cg06060754 chr5:176797920 RGS14 0.49 6.76 0.34 5.9e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs9368481 0.700 rs6911401 chr6:26913214 C/G cg12292205 chr6:26970375 C6orf41 0.45 7.68 0.38 1.66e-13 Autism spectrum disorder or schizophrenia; LIHC cis rs7264396 0.779 rs2425162 chr20:34429974 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -9.97 -0.47 1.01e-20 Total cholesterol levels; LIHC cis rs8014204 0.869 rs2070599 chr14:75361177 C/G cg11812906 chr14:75593930 NEK9 -0.34 -5.73 -0.3 2.17e-8 Caffeine consumption; LIHC cis rs17376456 0.825 rs28705226 chr5:93233135 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs7246657 0.943 rs4802136 chr19:37849811 T/A cg23950597 chr19:37808831 NA -0.44 -6.0 -0.31 5.01e-9 Coronary artery calcification; LIHC trans rs877282 1.000 rs12773872 chr10:771939 T/C cg22713356 chr15:30763199 NA 1.41 12.81 0.57 6.13e-31 Uric acid levels; LIHC cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg02990361 chr1:107599529 PRMT6 0.57 8.84 0.43 5.16e-17 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1577917 1.000 rs1857964 chr6:86635994 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.76 -0.5 1.82e-23 Response to antipsychotic treatment; LIHC cis rs9611565 0.571 rs2050032 chr22:42152429 C/T cg06634786 chr22:41940651 POLR3H 0.66 7.02 0.35 1.23e-11 Vitiligo; LIHC cis rs2074585 0.806 rs2657949 chr15:90950790 G/A cg22089800 chr15:90895588 ZNF774 0.56 7.53 0.38 4.59e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs9640161 0.750 rs59211922 chr7:150023790 T/G cg21361702 chr7:150065534 REPIN1 0.46 6.24 0.32 1.31e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs992157 0.560 rs12987130 chr2:219104990 T/C cg00012203 chr2:219082015 ARPC2 -0.88 -15.55 -0.64 1.32e-41 Colorectal cancer; LIHC trans rs9747201 1.000 rs3922470 chr17:80110159 C/T cg07393940 chr7:158741817 NA -0.57 -6.95 -0.35 1.85e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.86 7.66 0.38 1.98e-13 Platelet count; LIHC cis rs116095464 0.558 rs10067021 chr5:221490 C/T cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs8180040 0.966 rs3816779 chr3:47543389 C/T cg16586182 chr3:47516702 SCAP -0.6 -11.79 -0.54 3.71e-27 Colorectal cancer; LIHC cis rs17253792 0.732 rs75796044 chr14:56034128 C/T cg01858014 chr14:56050164 KTN1 -0.71 -7.56 -0.38 3.63e-13 Putamen volume; LIHC cis rs250677 0.687 rs41181 chr5:148444257 C/G cg18129178 chr5:148520854 ABLIM3 0.49 7.66 0.38 1.93e-13 Breast cancer; LIHC cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg05552183 chr6:42928497 GNMT 0.69 10.34 0.49 5.65e-22 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2439831 0.867 rs935901 chr15:43651256 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.74 8.9 0.43 3.22e-17 Lung cancer in ever smokers; LIHC cis rs1577917 0.958 rs7453105 chr6:86500761 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.7 -0.38 1.48e-13 Response to antipsychotic treatment; LIHC cis rs6964587 0.692 rs6970629 chr7:91846599 T/C cg17063962 chr7:91808500 NA 0.68 12.19 0.55 1.24e-28 Breast cancer; LIHC cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.32 -0.32 8.22e-10 Bipolar disorder and schizophrenia; LIHC trans rs116095464 0.558 rs7703803 chr5:292311 A/G cg00938859 chr5:1591904 SDHAP3 0.52 6.31 0.32 8.8e-10 Breast cancer; LIHC cis rs7258015 1.000 rs7254041 chr19:10448636 T/G cg13981319 chr19:10446556 ICAM3 0.46 7.21 0.36 3.68e-12 Systemic lupus erythematosus or rheumatoid arthritis; LIHC cis rs1198430 0.599 rs10917382 chr1:23780639 G/A cg13183780 chr1:23809682 ASAP3 -0.34 -6.03 -0.31 4.2e-9 Total cholesterol levels; LIHC cis rs17685 0.712 rs10271413 chr7:75754858 G/A cg04610667 chr7:75704037 NA -0.33 -5.98 -0.31 5.63e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6952808 0.594 rs3778965 chr7:2138296 G/A cg20295408 chr7:1910781 MAD1L1 -0.41 -5.98 -0.31 5.51e-9 Bipolar disorder and schizophrenia; LIHC cis rs797680 0.856 rs4847235 chr1:93627727 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.35 -6.13 -0.31 2.46e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs9814567 0.502 rs12634127 chr3:134256159 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.43 -8.17 -0.4 6.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6570726 0.934 rs9484995 chr6:145781114 T/A cg23711669 chr6:146136114 FBXO30 -0.45 -7.49 -0.38 5.87e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.522 rs1880556 chr7:65432544 T/C cg18876405 chr7:65276391 NA 0.54 9.04 0.44 1.22e-17 Aortic root size; LIHC cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1475718 0.526 rs10881586 chr9:137122724 C/T cg21243944 chr9:137118148 NA -0.43 -5.92 -0.3 7.76e-9 Immature fraction of reticulocytes;Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs12477438 0.501 rs12992218 chr2:99753834 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.24 0.61 1.91e-36 Chronic sinus infection; LIHC cis rs12477438 1.000 rs57846982 chr2:99921574 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -8.68 -0.42 1.67e-16 Chronic sinus infection; LIHC cis rs7116495 0.609 rs10450664 chr11:71636655 A/G cg10381502 chr11:71823885 C11orf51 -0.99 -8.28 -0.41 2.79e-15 Severe influenza A (H1N1) infection; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18211447 chr14:102771717 RAGE 0.4 6.1 0.31 2.88e-9 Cognitive function; LIHC cis rs11871801 0.918 rs36005199 chr17:40597555 A/G cg14558262 chr17:40713999 COASY 0.48 6.62 0.34 1.35e-10 Crohn's disease; LIHC cis rs66569888 0.789 rs17213510 chr2:106742778 T/C cg15412446 chr2:106886593 NA -0.7 -6.69 -0.34 9.31e-11 Facial morphology (factor 23); LIHC trans rs11157436 0.792 rs12433875 chr14:22622423 A/G cg13567813 chr19:50879636 NR1H2 0.41 6.11 0.31 2.77e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs2842992 0.872 rs2758330 chr6:160104844 G/T cg11366901 chr6:160182831 ACAT2 0.92 15.04 0.63 1.34e-39 Age-related macular degeneration (geographic atrophy); LIHC cis rs11711311 1.000 rs2566968 chr3:113474154 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.42 7.98 0.4 2.18e-14 IgG glycosylation; LIHC cis rs796364 0.906 rs1658810 chr2:200816382 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.73 8.35 0.41 1.66e-15 Schizophrenia; LIHC trans rs3780486 0.846 rs10116966 chr9:33122370 T/A cg20290983 chr6:43655470 MRPS18A 1.16 28.77 0.84 2.38e-93 IgG glycosylation; LIHC trans rs9641123 0.639 rs2051931 chr7:93243060 C/T cg09745688 chr16:2908918 PRSS22 -0.37 -6.4 -0.33 5.08e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs739401 0.611 rs2239899 chr11:3024624 A/G cg25174290 chr11:3078921 CARS -0.6 -9.14 -0.44 5.66e-18 Longevity; LIHC cis rs870825 0.616 rs7682505 chr4:185640648 C/T cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs1030877 0.557 rs2576752 chr2:105978761 A/G cg02079111 chr2:105885981 TGFBRAP1 0.52 8.36 0.41 1.56e-15 Obesity-related traits; LIHC cis rs9549367 0.789 rs9549718 chr13:113909822 A/G cg00898013 chr13:113819073 PROZ -0.43 -7.3 -0.37 2.08e-12 Platelet distribution width; LIHC cis rs7843479 1.000 rs7843479 chr8:21820813 G/T cg17168535 chr8:21777572 XPO7 0.43 6.66 0.34 1.11e-10 Mean corpuscular volume; LIHC cis rs11105298 0.891 rs10858898 chr12:89922111 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.3 -0.37 2.09e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs7116495 1.000 rs7106748 chr11:71645803 A/C cg26138937 chr11:71823887 C11orf51 -0.83 -8.35 -0.41 1.69e-15 Severe influenza A (H1N1) infection; LIHC cis rs67460515 0.563 rs13085336 chr3:160880599 G/A cg17135325 chr3:160939158 NMD3 0.6 8.77 0.43 8.32e-17 Parkinson's disease; LIHC cis rs12188164 0.543 rs2672722 chr5:453567 G/A cg26076054 chr5:421317 AHRR 0.27 5.94 0.31 6.85e-9 Cystic fibrosis severity; LIHC cis rs9790314 1.000 rs62279921 chr3:161065441 T/C cg03342759 chr3:160939853 NMD3 -0.66 -7.98 -0.4 2.21e-14 Morning vs. evening chronotype; LIHC cis rs4665809 0.941 rs11126336 chr2:26245931 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.71 -8.69 -0.43 1.49e-16 Gut microbiome composition (summer); LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.57 -8.06 -0.4 1.27e-14 Lymphocyte counts; LIHC cis rs9658691 0.607 rs34891735 chr10:90779212 A/T cg03111039 chr10:90751583 FAS;ACTA2 -0.86 -6.51 -0.33 2.76e-10 Mosquito bite size; LIHC cis rs4862307 0.514 rs7696176 chr4:185014390 A/G cg06737308 chr4:185021514 ENPP6 0.88 17.19 0.68 3.48e-48 Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs798554 0.718 rs1636247 chr7:2881917 A/G cg04166393 chr7:2884313 GNA12 0.55 8.52 0.42 5.03e-16 Height; LIHC trans rs116095464 0.558 rs13357299 chr5:242211 T/C cg00938859 chr5:1591904 SDHAP3 0.57 7.07 0.36 8.57e-12 Breast cancer; LIHC cis rs7602441 0.521 rs77940955 chr2:14767411 T/C cg06545361 chr2:14773388 FAM84A 0.52 5.96 0.31 6.34e-9 Visceral adipose tissue adjusted for BMI; LIHC cis rs9435341 0.762 rs72697623 chr1:107554269 G/A cg11070056 chr1:107600091 PRMT6 0.64 10.16 0.48 2.25e-21 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs11098499 0.954 rs10008459 chr4:120394231 T/C cg25214090 chr10:38739885 LOC399744 0.58 9.64 0.46 1.33e-19 Corneal astigmatism; LIHC cis rs9733 0.596 rs2175615 chr1:150624101 A/G cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs780096 0.565 rs11681351 chr2:27743423 G/A cg22903471 chr2:27725779 GCKR -0.53 -9.09 -0.44 8.01e-18 Total body bone mineral density; LIHC cis rs769267 0.965 rs2965191 chr19:19453521 T/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -9.87 -0.47 2.26e-20 Tonsillectomy; LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg11062466 chr8:58055876 NA 0.5 7.42 0.37 9.65e-13 Developmental language disorder (linguistic errors); LIHC cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 8.74 0.43 1.09e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs7165170 0.507 rs4932352 chr15:91145800 C/T cg26821196 chr15:91095069 CRTC3 0.32 5.9 0.3 8.95e-9 Crohn's disease;Inflammatory bowel disease; LIHC cis rs2580764 0.516 rs2860453 chr2:55270485 T/G cg09592903 chr2:55203963 RTN4 0.71 13.4 0.59 3.48e-33 Mean platelet volume; LIHC cis rs2070488 0.775 rs2051214 chr3:38560303 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.58 -9.21 -0.45 3.32e-18 Electrocardiographic conduction measures; LIHC cis rs60871478 0.945 rs4719279 chr7:813618 T/C cg05535760 chr7:792225 HEATR2 0.78 10.89 0.51 6.35e-24 Cerebrospinal P-tau181p levels; LIHC cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg18230493 chr5:56204884 C5orf35 -0.48 -6.52 -0.33 2.5e-10 Initial pursuit acceleration; LIHC cis rs6570726 0.935 rs451349 chr6:145820894 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17483139 chr1:1822401 GNB1 -0.45 -6.77 -0.34 5.55e-11 Pancreatic cancer; LIHC cis rs1552244 0.882 rs13075842 chr3:10055813 A/C cg08888203 chr3:10149979 C3orf24 0.46 5.96 0.31 6.31e-9 Alzheimer's disease; LIHC cis rs7208859 0.623 rs11658945 chr17:29122509 T/C cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7188697 0.922 rs9923491 chr16:58603176 T/G cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs523522 0.962 rs11065149 chr12:120956963 G/A cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC cis rs12701220 0.894 rs10257744 chr7:1045612 C/T cg04498913 chr7:1135747 C7orf50 0.37 5.72 0.3 2.29e-8 Bronchopulmonary dysplasia; LIHC cis rs10870270 0.913 rs4880326 chr10:133745547 C/A cg08754478 chr10:133766260 PPP2R2D -0.54 -7.91 -0.39 3.5e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs4820539 0.611 rs28451783 chr22:23488569 G/T cg14186256 chr22:23484241 RTDR1 0.82 9.77 0.47 4.8e-20 Bone mineral density; LIHC cis rs3762637 1.000 rs78381804 chr3:122222262 A/T cg24169773 chr3:122142474 KPNA1 -0.47 -9.25 -0.45 2.41e-18 LDL cholesterol levels; LIHC trans rs11098499 0.789 rs9991166 chr4:120237851 G/A cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg22903471 chr2:27725779 GCKR -0.5 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg10774155 chr7:65338427 VKORC1L1 0.45 6.71 0.34 7.86e-11 Calcium levels; LIHC cis rs9322817 0.691 rs2034821 chr6:105219537 C/T cg02098413 chr6:105308735 HACE1 -0.42 -7.55 -0.38 4.01e-13 Thyroid stimulating hormone; LIHC cis rs763121 0.853 rs7289855 chr22:39042221 G/T cg14440974 chr22:39074834 NA -0.42 -6.7 -0.34 8.5e-11 Menopause (age at onset); LIHC cis rs2204008 0.774 rs12810027 chr12:38212165 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs881375 0.678 rs4836834 chr9:123665901 T/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.4 0.33 5.18e-10 Rheumatoid arthritis; LIHC cis rs10791097 0.694 rs10894273 chr11:130742155 G/T cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12220238 1.000 rs12359456 chr10:75937994 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.71 6.78 0.34 5.19e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9916302 0.904 rs2168785 chr17:37407135 C/T cg07936489 chr17:37558343 FBXL20 -0.82 -13.19 -0.58 2.21e-32 Glomerular filtration rate (creatinine); LIHC cis rs72781680 0.716 rs72788206 chr2:24084989 T/C cg08917208 chr2:24149416 ATAD2B 0.64 6.58 0.34 1.81e-10 Lymphocyte counts; LIHC cis rs7944584 0.588 rs2697923 chr11:47363215 G/T cg20307385 chr11:47447363 PSMC3 -0.55 -5.9 -0.3 8.8e-9 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6565180 0.888 rs12447833 chr16:30390314 T/C cg17640201 chr16:30407289 ZNF48 0.76 12.27 0.55 6.16e-29 Tonsillectomy; LIHC cis rs10751667 0.714 rs7396700 chr11:963863 A/C cg06064525 chr11:970664 AP2A2 -0.56 -14.82 -0.63 1.04e-38 Alzheimer's disease (late onset); LIHC cis rs853679 0.517 rs9380062 chr6:28137569 G/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs7635838 0.819 rs4684072 chr3:11514860 A/G cg00170343 chr3:11313890 ATG7 0.41 6.41 0.33 4.91e-10 HDL cholesterol; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23945273 chr4:120987944 MAD2L1 0.45 6.13 0.31 2.46e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs35146811 0.961 rs1880949 chr7:99722266 A/C cg13334819 chr7:99746414 C7orf59 0.59 8.51 0.42 5.43e-16 Coronary artery disease; LIHC cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg13607699 chr17:42295918 UBTF -0.57 -9.8 -0.47 3.84e-20 Total body bone mineral density; LIHC cis rs477895 0.838 rs35090903 chr11:64000598 C/T cg04317338 chr11:64019027 PLCB3 0.86 10.59 0.5 7.21e-23 Mean platelet volume; LIHC cis rs1801251 0.778 rs2250654 chr2:233752376 A/T cg08000102 chr2:233561755 GIGYF2 -0.71 -10.39 -0.49 3.81e-22 Coronary artery disease; LIHC cis rs9682041 0.932 rs7631221 chr3:170069893 A/G cg11886554 chr3:170076028 SKIL 0.76 6.68 0.34 9.7e-11 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs2607426 0.681 rs2257613 chr19:41284004 C/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.55 -6.29 -0.32 9.85e-10 Blood protein levels; LIHC cis rs4920343 0.698 rs669138 chr1:19088899 C/T cg19637330 chr1:19110922 NA 0.33 5.99 0.31 5.25e-9 Knee osteoarthritis; LIHC cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.43 5.89 0.3 9.33e-9 Electroencephalogram traits; LIHC trans rs61931739 0.500 rs34107854 chr12:34482333 C/A cg26384229 chr12:38710491 ALG10B 0.8 9.89 0.47 1.85e-20 Morning vs. evening chronotype; LIHC cis rs2980439 0.870 rs2945230 chr8:8109936 A/G cg08975724 chr8:8085496 FLJ10661 0.46 6.86 0.35 3.16e-11 Neuroticism; LIHC cis rs6141600 0.760 rs2590986 chr20:34686496 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.38 -5.87 -0.3 1.05e-8 Height;Hip circumference; LIHC cis rs798766 0.723 rs3134865 chr4:1723279 T/C cg21231739 chr4:1642635 FAM53A -0.36 -5.76 -0.3 1.86e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs4906332 1.000 rs3783398 chr14:103949378 C/T cg19000871 chr14:103996768 TRMT61A 0.43 7.24 0.36 3.04e-12 Coronary artery disease; LIHC cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg11890956 chr21:40555474 PSMG1 -0.49 -7.93 -0.39 3.13e-14 Cognitive function; LIHC cis rs2412459 0.803 rs28369403 chr15:40277603 G/A cg02712587 chr15:40268421 EIF2AK4 -0.54 -5.76 -0.3 1.84e-8 Response to haloperidol in psychosis; LIHC cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.74 -12.81 -0.57 5.99e-31 Prudent dietary pattern; LIHC cis rs12497850 0.931 rs7430198 chr3:48988760 T/C cg07636037 chr3:49044803 WDR6 0.93 16.31 0.66 1.25e-44 Parkinson's disease; LIHC cis rs7613875 0.578 rs4688753 chr3:50074773 A/G cg24110177 chr3:50126178 RBM5 0.56 9.16 0.44 4.94e-18 Body mass index; LIHC cis rs986417 1.000 rs996285 chr14:60869837 T/G cg27398547 chr14:60952738 C14orf39 -0.71 -8.02 -0.4 1.74e-14 Gut microbiota (bacterial taxa); LIHC cis rs9549367 0.789 rs9549701 chr13:113881752 G/C cg00898013 chr13:113819073 PROZ -0.43 -7.46 -0.37 7.44e-13 Platelet distribution width; LIHC trans rs9929218 0.953 rs2902323 chr16:68736292 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.65 -9.19 -0.45 3.83e-18 Colorectal cancer; LIHC cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg09913183 chr17:42254507 C17orf65;ASB16 0.8 12.56 0.56 4.96e-30 Total body bone mineral density; LIHC cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.5 7.04 0.36 1.04e-11 Height; LIHC cis rs2066819 1.000 rs2695782 chr12:56722830 C/T cg26734620 chr12:56694298 CS -1.04 -10.23 -0.48 1.3e-21 Psoriasis vulgaris; LIHC trans rs1005277 0.579 rs1740737 chr10:38499365 G/T cg27523141 chr10:43048294 ZNF37B 0.38 6.42 0.33 4.69e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6748734 0.843 rs6749674 chr2:241834501 G/C cg04034577 chr2:241836375 C2orf54 -0.4 -8.1 -0.4 9.96e-15 Urinary metabolites; LIHC cis rs9640161 0.789 rs34311995 chr7:150059255 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.44 -0.42 8.98e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs9837602 0.529 rs793458 chr3:99520169 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.97 0.35 1.59e-11 Breast cancer; LIHC cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg18404041 chr3:52824283 ITIH1 -0.58 -9.65 -0.46 1.16e-19 Electroencephalogram traits; LIHC cis rs16912285 0.688 rs7929701 chr11:24357964 A/C ch.11.24196551F chr11:24239977 NA 0.72 8.36 0.41 1.66e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs6598955 0.724 rs10902731 chr1:26600793 A/G cg00852783 chr1:26633632 UBXN11 0.51 8.63 0.42 2.31e-16 Obesity-related traits; LIHC cis rs9611565 0.525 rs9611549 chr22:41705909 C/G cg03806693 chr22:41940476 POLR3H -0.71 -8.44 -0.42 8.82e-16 Vitiligo; LIHC cis rs875971 0.830 rs28714531 chr7:65968237 G/A cg18252515 chr7:66147081 NA -0.46 -6.79 -0.34 4.96e-11 Aortic root size; LIHC cis rs2732480 0.500 rs2450991 chr12:48651621 A/G cg21466736 chr12:48725269 NA -0.71 -10.87 -0.51 7.92e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs11088226 0.645 rs2833904 chr21:33941089 T/C cg09050820 chr6:167586206 TCP10L2 0.87 13.29 0.58 8.98e-33 Gastritis; LIHC trans rs2243480 1.000 rs464895 chr7:65527106 A/G cg10756647 chr7:56101905 PSPH 1.08 13.35 0.59 5.31e-33 Diabetic kidney disease; LIHC cis rs918629 0.567 rs56219066 chr5:95242931 T/C cg10483112 chr5:95245456 ELL2 -0.37 -6.88 -0.35 2.79e-11 IgG glycosylation; LIHC trans rs7674212 0.570 rs2711898 chr4:104063071 C/T cg16471864 chr4:38666270 KLF3;FLJ13197 -0.44 -6.25 -0.32 1.2e-9 Type 2 diabetes; LIHC cis rs11758351 1.000 rs80259160 chr6:26190199 C/T cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00429477 chr12:6798907 ZNF384 -0.47 -6.4 -0.33 5.22e-10 Bilirubin levels; LIHC cis rs7255 0.538 rs2289081 chr2:20881840 G/C cg14780466 chr2:20870812 GDF7 -0.28 -6.0 -0.31 5.11e-9 Barrett's esophagus or Esophageal adenocarcinoma;Esophageal adenocarcinoma; LIHC cis rs12048904 0.647 rs7528268 chr1:101329295 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 10.32 0.49 6.33e-22 Multiple sclerosis; LIHC cis rs7072216 0.763 rs6584201 chr10:100170209 T/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.45 -0.33 3.83e-10 Metabolite levels; LIHC cis rs17685 0.587 rs1623759 chr7:75724679 A/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.17 -0.32 1.97e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6089584 0.888 rs6587283 chr20:60613727 A/C cg13770153 chr20:60521292 NA -0.34 -6.74 -0.34 6.71e-11 Body mass index; LIHC cis rs8056893 0.714 rs9931501 chr16:68402686 A/G cg02226672 chr16:68398533 SMPD3 0.43 5.97 0.31 5.81e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg03452623 chr4:187889614 NA -0.35 -9.0 -0.44 1.57e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs1008375 0.897 rs2315554 chr4:17660407 T/C cg02297831 chr4:17616191 MED28 0.43 5.84 0.3 1.22e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10744422 1.000 rs4759387 chr12:123377569 C/T cg18912006 chr12:123335444 HIP1R -0.59 -6.86 -0.35 3.2e-11 Schizophrenia; LIHC trans rs1441147 0.764 rs2696344 chr2:182533211 C/G cg00626466 chr12:65153982 GNS 0.44 6.32 0.32 8.19e-10 Lung function (FVC);Lung function (FEV1); LIHC cis rs7552404 1.000 rs211718 chr1:76106675 C/T cg03433033 chr1:76189801 ACADM 0.65 9.43 0.45 6.43e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7238033 0.624 rs9949609 chr18:43313128 C/G cg20610511 chr18:43302872 SLC14A1 0.37 6.24 0.32 1.31e-9 Bladder cancer; LIHC cis rs637571 0.584 rs594689 chr11:65635559 G/A cg26695010 chr11:65641043 EFEMP2 0.59 8.39 0.41 1.3e-15 Eosinophil percentage of white cells; LIHC cis rs12477438 0.871 rs62156364 chr2:99695097 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -8.3 -0.41 2.4e-15 Chronic sinus infection; LIHC cis rs595982 0.559 rs73061643 chr19:49368151 A/G cg15549821 chr19:49342101 PLEKHA4 -0.63 -5.84 -0.3 1.24e-8 Red cell distribution width; LIHC cis rs6088590 1.000 rs6119535 chr20:33442138 A/C cg06115741 chr20:33292138 TP53INP2 0.59 7.98 0.4 2.16e-14 Coronary artery disease; LIHC cis rs765787 0.530 rs2668737 chr15:45522799 C/T cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.74 -0.3 2.12e-8 Uric acid levels; LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg27094323 chr7:1216898 NA -0.4 -5.78 -0.3 1.68e-8 Longevity;Endometriosis; LIHC cis rs2282802 0.651 rs6863474 chr5:139630862 C/T cg26211634 chr5:139558579 C5orf32 0.39 6.08 0.31 3.14e-9 Intelligence (multi-trait analysis); LIHC cis rs703842 1.000 rs8181644 chr12:58173466 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.86 14.21 0.61 2.35e-36 Multiple sclerosis; LIHC cis rs8060686 0.641 rs8059305 chr16:68036666 A/C cg05110241 chr16:68378359 PRMT7 -0.48 -5.98 -0.31 5.56e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs11653357 1.000 rs11653357 chr17:33923607 G/A cg20932281 chr17:33905541 PEX12 0.56 7.23 0.36 3.28e-12 Platelet distribution width;Platelet count; LIHC cis rs12101261 1.000 rs1023586 chr14:81462283 T/C cg06600135 chr14:81408086 NA 0.37 6.33 0.32 7.5e-10 Graves' disease; LIHC cis rs2370759 0.945 rs74625866 chr10:32597618 A/T cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs67981189 0.593 rs7160958 chr14:71442526 C/A cg15816911 chr14:71606274 NA 0.41 6.55 0.33 2.17e-10 Schizophrenia; LIHC cis rs9910055 0.530 rs8072954 chr17:42294722 G/A cg10896456 chr17:42255109 ASB16;C17orf65 0.42 7.32 0.37 1.8e-12 Total body bone mineral density; LIHC cis rs4319547 1.000 rs7307735 chr12:123087442 A/G cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.02 -0.4 1.7e-14 Body mass index; LIHC cis rs922107 0.713 rs10922663 chr1:90032893 C/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.7 -0.38 1.48e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs9291683 0.552 rs17187075 chr4:9990328 G/C cg11266682 chr4:10021025 SLC2A9 0.31 6.47 0.33 3.33e-10 Bone mineral density; LIHC cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg03806693 chr22:41940476 POLR3H 1.09 12.91 0.57 2.49e-31 Vitiligo; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg24693881 chr1:107596107 NA -0.53 -9.26 -0.45 2.24e-18 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10769945 0.606 rs217236 chr11:1981259 T/C cg23202291 chr11:1979235 NA -0.48 -7.32 -0.37 1.81e-12 DNA methylation (variation); LIHC cis rs8114671 0.562 rs2223881 chr20:33506463 A/C cg07148914 chr20:33460835 GGT7 0.66 10.12 0.48 3.16e-21 Height; LIHC cis rs7447593 0.518 rs4074995 chr5:176797343 C/T cg16006841 chr5:176797999 RGS14 0.82 13.16 0.58 2.8099999999999997e-32 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs7829975 0.564 rs2921057 chr8:8318667 C/T cg08975724 chr8:8085496 FLJ10661 0.57 8.84 0.43 5.25e-17 Mood instability; LIHC cis rs7511006 0.859 rs7292228 chr22:50649560 C/G cg16473166 chr22:50639996 SELO 0.57 8.51 0.42 5.61e-16 Obesity-related traits; LIHC cis rs1005277 0.579 rs1780122 chr10:38529509 C/A cg25427524 chr10:38739819 LOC399744 -0.72 -14.15 -0.61 4.37e-36 Extrinsic epigenetic age acceleration; LIHC cis rs17854409 0.803 rs1063246 chr20:61472116 G/A cg07645718 chr20:61493192 TCFL5 0.79 6.45 0.33 3.85e-10 Obesity-related traits; LIHC trans rs6598955 0.671 rs17162105 chr1:26591255 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.59 -0.42 3.07e-16 Obesity-related traits; LIHC cis rs7208859 0.524 rs73988172 chr17:29086332 A/C cg13385521 chr17:29058706 SUZ12P 0.8 8.0 0.4 2e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3812831 0.695 rs7998546 chr13:114939914 C/G cg03343631 chr13:114764489 RASA3 -0.28 -5.74 -0.3 2.04e-8 Schizophrenia; LIHC cis rs3749237 0.615 rs6792911 chr3:49429856 C/T cg03060546 chr3:49711283 APEH 0.61 9.77 0.47 4.96e-20 Resting heart rate; LIHC cis rs35883536 1.000 rs4907918 chr1:101094609 A/G cg14515779 chr1:101123966 NA 0.67 13.35 0.59 5.12e-33 Monocyte count; LIHC cis rs870825 0.929 rs56106324 chr4:185589901 C/A cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs11583043 0.918 rs56402739 chr1:101397133 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.52 0.46 3.1400000000000002e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7647973 0.769 rs6772452 chr3:49040462 A/G cg07636037 chr3:49044803 WDR6 0.79 10.64 0.5 4.86e-23 Menarche (age at onset); LIHC cis rs6701037 0.748 rs2685 chr1:175127771 A/G cg17845761 chr1:175162550 KIAA0040 0.42 7.21 0.36 3.57e-12 Alcohol dependence; LIHC cis rs7107174 1.000 rs10899495 chr11:78123293 C/T cg02023728 chr11:77925099 USP35 0.41 7.41 0.37 1.02e-12 Testicular germ cell tumor; LIHC cis rs10504229 0.680 rs11777459 chr8:58044241 A/T cg02290350 chr8:58132656 NA 0.31 6.59 0.34 1.68e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs400736 0.930 rs226251 chr1:8024690 T/C cg25007680 chr1:8021821 PARK7 0.61 9.65 0.46 1.21e-19 Response to antidepressants and depression; LIHC cis rs4589502 0.841 rs55855162 chr15:67140523 C/A cg09911534 chr15:67153556 NA -0.46 -6.11 -0.31 2.7e-9 Lung cancer (smoking interaction); LIHC cis rs7777484 0.534 rs2533886 chr7:2834869 C/T cg19717773 chr7:2847554 GNA12 -0.45 -8.86 -0.43 4.29e-17 Height; LIHC cis rs11792861 0.926 rs72607174 chr9:111899132 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.6 8.32 0.41 2.14e-15 Menarche (age at onset); LIHC cis rs34779708 0.966 rs12761675 chr10:35438337 C/T cg03585969 chr10:35415529 CREM -0.85 -12.86 -0.57 3.98e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7909074 1.000 rs4948927 chr10:45397071 G/A cg04218760 chr10:45406644 TMEM72 -0.23 -7.26 -0.37 2.67e-12 Mean corpuscular volume; LIHC cis rs17021463 0.872 rs11097417 chr4:95268071 C/T cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.1 -0.4 9.83e-15 Testicular germ cell tumor; LIHC cis rs7192750 0.586 rs2335710 chr16:71923181 C/G cg06353428 chr16:71660113 MARVELD3 -0.82 -9.16 -0.44 4.84e-18 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg26874164 chr19:58962979 ZNF324B -0.6 -9.42 -0.45 7.03e-19 Uric acid clearance; LIHC cis rs3768617 0.811 rs12738377 chr1:183031256 C/T ch.1.3577855R chr1:183094577 LAMC1 0.48 7.59 0.38 3.12e-13 Fuchs's corneal dystrophy; LIHC cis rs4555082 0.957 rs2816627 chr14:105736109 A/G cg06808227 chr14:105710500 BRF1 -0.62 -8.78 -0.43 7.87e-17 Mean platelet volume;Platelet distribution width; LIHC trans rs6866721 0.791 rs7724674 chr5:116217033 T/C cg07571379 chr11:134631427 NA -0.28 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs1707322 0.686 rs11211179 chr1:46228082 A/C cg06784218 chr1:46089804 CCDC17 0.39 7.17 0.36 4.68e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3770081 1.000 rs12614260 chr2:86303079 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.88 -8.69 -0.43 1.49e-16 Facial emotion recognition (sad faces); LIHC cis rs2412459 1.000 rs8023482 chr15:40307095 A/C cg01081584 chr15:40268610 EIF2AK4 -0.61 -8.04 -0.4 1.52e-14 Response to haloperidol in psychosis; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg13126279 chr21:47581558 C21orf56 0.44 7.22 0.36 3.46e-12 Testicular germ cell tumor; LIHC cis rs3741404 0.609 rs641378 chr11:63869493 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.67 10.83 0.51 1.04e-23 Platelet count; LIHC cis rs1144333 1.000 rs17097863 chr1:76468787 T/G cg03433033 chr1:76189801 ACADM 0.51 7.44 0.37 8.08e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs7937682 1.000 rs7121011 chr11:111568681 C/T cg09085632 chr11:111637200 PPP2R1B 1.09 13.26 0.58 1.12e-32 Primary sclerosing cholangitis; LIHC cis rs597539 0.690 rs497149 chr11:68626639 A/T cg06028808 chr11:68637592 NA 0.43 5.89 0.3 9.25e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs3806843 1.000 rs3733710 chr5:140167463 C/T cg19875535 chr5:140030758 IK 0.36 5.89 0.3 9.15e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7617773 0.817 rs9853804 chr3:48327729 T/C cg11946769 chr3:48343235 NME6 0.87 11.32 0.52 1.96e-25 Coronary artery disease; LIHC cis rs911119 0.913 rs13037490 chr20:23583725 T/C cg16589663 chr20:23618590 CST3 0.74 7.46 0.37 7.4e-13 Chronic kidney disease; LIHC cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg12310025 chr6:25882481 NA -0.63 -7.88 -0.39 4.3e-14 Intelligence (multi-trait analysis); LIHC cis rs1348850 0.874 rs2166558 chr2:178373652 G/T cg27490568 chr2:178487706 NA 0.36 5.72 0.3 2.37e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs11931598 0.511 rs4689576 chr4:7025523 T/C cg26116260 chr4:7069785 GRPEL1 0.53 8.95 0.44 2.24e-17 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs6714710 0.603 rs10432626 chr2:98561153 C/A cg26665480 chr2:98280029 ACTR1B 0.43 5.99 0.31 5.27e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs7264396 0.515 rs2425134 chr20:34339439 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.59 -8.45 -0.42 8.37e-16 Total cholesterol levels; LIHC cis rs7572733 0.515 rs35730302 chr2:198818626 A/T cg10820045 chr2:198174542 NA -0.49 -7.38 -0.37 1.21e-12 Dermatomyositis; LIHC cis rs778371 0.723 rs1973675 chr2:233636450 C/T cg08000102 chr2:233561755 GIGYF2 -0.88 -14.85 -0.63 7.3e-39 Schizophrenia; LIHC cis rs2404602 0.716 rs8030411 chr15:76699855 A/G cg23625390 chr15:77176239 SCAPER 0.36 6.03 0.31 4.17e-9 Blood metabolite levels; LIHC cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg08280861 chr8:58055591 NA 0.53 6.43 0.33 4.34e-10 Developmental language disorder (linguistic errors); LIHC cis rs61990749 0.544 rs2544566 chr14:78181738 C/G cg23188588 chr14:78226832 SNW1;C14orf178 0.62 10.32 0.49 6.7e-22 Fibroblast growth factor basic levels; LIHC cis rs9733 0.818 rs12130363 chr1:150688596 T/C cg17724175 chr1:150552817 MCL1 -0.38 -7.85 -0.39 5.49e-14 Tonsillectomy; LIHC cis rs370915 0.542 rs7687552 chr4:187837862 G/C cg19519643 chr4:187840862 NA -0.5 -8.72 -0.43 1.19e-16 Gout; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg16632132 chr16:1122873 LOC146336 0.44 6.11 0.31 2.72e-9 Lung function (FEV1/FVC); LIHC cis rs11212260 0.678 rs11212204 chr11:107267630 G/T cg25435332 chr11:107328525 CWF19L2 0.72 8.26 0.41 3.14e-15 IgG glycosylation; LIHC cis rs1185460 0.967 rs1786141 chr11:118938315 C/T cg23280166 chr11:118938394 VPS11 0.6 8.31 0.41 2.2e-15 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20598768 chr1:154193039 C1orf43;UBAP2L 0.5 6.82 0.35 4.07e-11 Lung function (FEV1/FVC); LIHC cis rs9916302 0.904 rs7223331 chr17:37482930 A/G cg03013999 chr17:37608204 MED1 -0.36 -5.99 -0.31 5.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs6570726 0.875 rs1883407 chr6:145823432 T/C cg23711669 chr6:146136114 FBXO30 0.54 9.75 0.47 5.8e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs6835098 1.000 rs9990666 chr4:174083150 G/T cg08422745 chr4:174089978 GALNT7 -0.32 -5.71 -0.3 2.43e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs9628987 0.539 rs9628991 chr1:8424039 C/G cg20416874 chr1:8611966 RERE 0.49 5.94 0.31 7.18e-9 Breast cancer; LIHC cis rs7089973 0.604 rs7904188 chr10:116610271 G/C cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs875971 0.545 rs11770063 chr7:65783016 G/A cg26939375 chr7:64535504 NA 0.4 6.34 0.32 7.06e-10 Aortic root size; LIHC cis rs34540877 1.000 rs34131970 chr19:33144107 A/G cg22980127 chr19:33182716 NUDT19 0.89 6.22 0.32 1.46e-9 Red cell distribution width; LIHC cis rs11252926 0.931 rs4881399 chr10:567325 A/G cg16346588 chr10:242978 ZMYND11 0.46 5.93 0.31 7.22e-9 Psychosis in Alzheimer's disease; LIHC cis rs11690935 0.959 rs12185567 chr2:172560729 A/C cg13550731 chr2:172543902 DYNC1I2 0.92 17.86 0.69 7.39e-51 Schizophrenia; LIHC cis rs9911578 0.935 rs9911753 chr17:56983174 G/A cg12560992 chr17:57184187 TRIM37 0.9 15.97 0.65 2.78e-43 Intelligence (multi-trait analysis); LIHC trans rs875971 0.545 rs73142245 chr7:65691649 A/G cg26939375 chr7:64535504 NA 0.4 6.31 0.32 8.87e-10 Aortic root size; LIHC cis rs1801251 0.752 rs2675966 chr2:233735543 T/C cg25237894 chr2:233734115 C2orf82 -0.59 -11.92 -0.54 1.29e-27 Coronary artery disease; LIHC cis rs8114671 0.562 rs3818273 chr20:33509275 G/A cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.04e-19 Height; LIHC cis rs8077889 0.917 rs6503479 chr17:41917003 A/G cg26893861 chr17:41843967 DUSP3 0.94 10.83 0.51 1.06e-23 Triglycerides; LIHC trans rs9921222 0.585 rs7195617 chr16:376781 A/G cg03370490 chr11:1380305 NA 0.25 6.04 0.31 3.99e-9 Bone mineral density (spine);Bone mineral density; LIHC cis rs6594499 0.872 rs10038058 chr5:110443281 A/G cg04022379 chr5:110408740 TSLP 0.49 8.25 0.41 3.52e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs860295 0.729 rs4971072 chr1:155273869 G/A cg02153340 chr1:155202674 NA 0.33 5.88 0.3 9.64e-9 Body mass index; LIHC cis rs6540556 0.859 rs11119340 chr1:209940560 A/T cg05527609 chr1:210001259 C1orf107 0.68 9.71 0.46 7.58e-20 Red blood cell count; LIHC cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg21448741 chr8:58168803 NA 0.35 5.83 0.3 1.29e-8 Developmental language disorder (linguistic errors); LIHC cis rs2380220 0.541 rs72928283 chr6:96082490 A/C cg15832292 chr6:96025679 MANEA -0.71 -8.52 -0.42 5e-16 Behavioural disinhibition (generation interaction); LIHC cis rs10791097 0.694 rs876641 chr11:130752040 A/C cg12179176 chr11:130786555 SNX19 0.8 12.72 0.57 1.25e-30 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1799949 1.000 rs8070085 chr17:41341984 C/T cg05368731 chr17:41323189 NBR1 -0.66 -11.14 -0.52 8.38e-25 Menopause (age at onset); LIHC cis rs4908768 0.906 rs12402539 chr1:8538303 C/A cg25722041 chr1:8623473 RERE 0.41 6.02 0.31 4.5e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg05484376 chr2:27715224 FNDC4 0.38 6.42 0.33 4.69e-10 Total body bone mineral density; LIHC cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg01448562 chr3:133502909 NA -0.42 -6.66 -0.34 1.12e-10 Iron status biomarkers; LIHC cis rs2075371 0.966 rs2544223 chr7:133995787 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.56 0.38 3.73e-13 Mean platelet volume; LIHC cis rs2302190 0.882 rs7221205 chr17:56485799 G/A cg05425664 chr17:57184151 TRIM37 -0.48 -6.05 -0.31 3.85e-9 Vitamin D levels; LIHC cis rs2635047 0.565 rs2571004 chr18:44710302 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.93 0.31 7.28e-9 Educational attainment; LIHC cis rs2180341 0.961 rs910720 chr6:127619070 T/C cg27446573 chr6:127587934 RNF146 1.03 15.95 0.65 3.18e-43 Breast cancer; LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg24449463 chr1:168025552 DCAF6 0.46 6.11 0.31 2.69e-9 Hepatitis; LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg07424592 chr7:64974309 NA 0.46 7.01 0.35 1.25e-11 Calcium levels; LIHC cis rs600806 0.815 rs10858097 chr1:109967324 C/A cg16275483 chr1:110013120 SYPL2 -0.47 -5.86 -0.3 1.09e-8 Intelligence (multi-trait analysis); LIHC trans rs9929218 1.000 rs28549017 chr16:68758828 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -9.19 -0.45 4.01e-18 Colorectal cancer; LIHC cis rs17376456 0.569 rs35878747 chr5:93094070 C/A cg25358565 chr5:93447407 FAM172A 0.8 7.68 0.38 1.63e-13 Diabetic retinopathy; LIHC cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg00656387 chr3:40428638 ENTPD3 -0.43 -7.18 -0.36 4.38e-12 Renal cell carcinoma; LIHC cis rs611744 0.608 rs1448152 chr8:109278249 C/T cg18478394 chr8:109455254 TTC35 0.44 7.57 0.38 3.6e-13 Dupuytren's disease; LIHC cis rs1775715 0.707 rs1541261 chr10:32179523 G/A cg14930904 chr10:32216787 ARHGAP12 0.35 6.07 0.31 3.35e-9 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs1499614 1.000 rs1882655 chr7:66147057 T/C cg05590025 chr7:65112418 INTS4L2 0.56 6.09 0.31 3.04e-9 Gout; LIHC trans rs9397585 0.599 rs685826 chr6:153411255 C/T cg13798721 chr14:105190477 ADSSL1 -0.45 -6.25 -0.32 1.22e-9 Body mass index; LIHC cis rs10751667 0.621 rs10794351 chr11:946228 C/T cg06064525 chr11:970664 AP2A2 -0.56 -15.07 -0.63 1.01e-39 Alzheimer's disease (late onset); LIHC cis rs2115630 0.902 rs8023276 chr15:85219638 C/T cg12501888 chr15:85177176 SCAND2 -0.52 -8.0 -0.4 1.94e-14 P wave terminal force; LIHC cis rs4713118 0.513 rs149975 chr6:27986340 G/A cg16479474 chr6:28041457 NA 0.38 6.29 0.32 9.81e-10 Parkinson's disease; LIHC cis rs2115630 0.936 rs6496318 chr15:85215229 C/T cg12501888 chr15:85177176 SCAND2 -0.52 -8.0 -0.4 1.94e-14 P wave terminal force; LIHC cis rs3096299 0.933 rs889576 chr16:89429653 A/G cg06640241 chr16:89574553 SPG7 -0.58 -9.2 -0.45 3.73e-18 Multiple myeloma (IgH translocation); LIHC cis rs7659604 0.539 rs11098646 chr4:122729301 T/C cg20573242 chr4:122745356 CCNA2 0.53 7.69 0.38 1.58e-13 Type 2 diabetes; LIHC cis rs3106136 0.967 rs12646184 chr4:95183216 A/G cg11021082 chr4:95130006 SMARCAD1 0.44 7.82 0.39 6.7e-14 Capecitabine sensitivity; LIHC cis rs250677 0.687 rs36046 chr5:148441257 A/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.48 -0.38 6.18e-13 Breast cancer; LIHC cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs265548 0.608 rs36690 chr19:17910483 C/T cg21960279 chr19:17905606 B3GNT3 0.52 8.2 0.41 4.82e-15 Tumor biomarkers; LIHC cis rs7582720 1.000 rs72934554 chr2:203987806 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs709400 0.597 rs1013650 chr14:103909203 G/A cg26031613 chr14:104095156 KLC1 0.72 9.71 0.46 7.42e-20 Body mass index; LIHC cis rs7927771 0.524 rs4752865 chr11:47759841 G/A cg20307385 chr11:47447363 PSMC3 -0.65 -9.85 -0.47 2.68e-20 Subjective well-being; LIHC cis rs9916302 0.904 rs6503519 chr17:37706578 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.25 -0.58 1.21e-32 Glomerular filtration rate (creatinine); LIHC cis rs3806843 0.648 rs702399 chr5:140024432 C/T cg16577123 chr5:140027231 NDUFA2;IK -0.42 -5.97 -0.31 6.07e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs11039798 1.000 rs8188963 chr11:48685693 C/A cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs6463523 0.933 rs6974151 chr7:758269 T/C cg06242242 chr7:766104 PRKAR1B;HEATR2 0.95 15.88 0.65 6.22e-43 Subjective well-being; LIHC cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg19318889 chr4:1322082 MAEA -0.46 -7.59 -0.38 3.09e-13 Obesity-related traits; LIHC cis rs7100689 0.753 rs4934125 chr10:82147466 T/C cg00277334 chr10:82204260 NA -0.54 -6.84 -0.35 3.68e-11 Post bronchodilator FEV1; LIHC trans rs3960554 1.000 rs3960554 chr7:75845597 G/T cg19862616 chr7:65841803 NCRNA00174 0.62 9.34 0.45 1.3e-18 Eotaxin levels; LIHC cis rs7772486 0.641 rs2253757 chr6:146199686 C/T cg05347473 chr6:146136440 FBXO30 0.47 7.03 0.36 1.1e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs12142240 0.698 rs13374893 chr1:46843800 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.81 0.3 1.45e-8 Menopause (age at onset); LIHC cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC trans rs875971 0.964 rs55748098 chr7:65763618 T/C cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.16e-10 Aortic root size; LIHC cis rs2073300 0.793 rs6114094 chr20:23434267 A/G cg12062639 chr20:23401060 NAPB 0.74 8.92 0.43 2.87e-17 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC cis rs61774743 0.681 rs10749805 chr1:41850182 C/T cg08462924 chr1:41848221 NA 0.34 5.86 0.3 1.1e-8 Intelligence (multi-trait analysis); LIHC cis rs2439831 0.867 rs689616 chr15:43761901 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.59 0.59 6.27e-34 Lung cancer in ever smokers; LIHC cis rs6545883 1.000 rs778762 chr2:61782921 G/T cg14146966 chr2:61757674 XPO1 0.49 8.33 0.41 1.96e-15 Tuberculosis; LIHC cis rs9303401 0.646 rs7342863 chr17:57227010 G/A cg12560992 chr17:57184187 TRIM37 0.53 7.29 0.37 2.1e-12 Cognitive test performance; LIHC trans rs3960554 0.932 rs4728614 chr7:75841589 A/G cg19862616 chr7:65841803 NCRNA00174 -0.52 -7.1 -0.36 7.33e-12 Eotaxin levels; LIHC cis rs61677309 1.000 rs1074459 chr11:118155997 T/C cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs9303401 1.000 rs1390006 chr17:56890663 C/T cg25039879 chr17:56429692 SUPT4H1 -0.5 -7.05 -0.36 1.01e-11 Cognitive test performance; LIHC cis rs1046896 0.553 rs3744160 chr17:80828303 G/A cg22027946 chr17:80790580 TBCD;ZNF750 0.52 7.57 0.38 3.4e-13 Glycated hemoglobin levels; LIHC cis rs77861329 1.000 rs352153 chr3:52211184 A/T cg08692210 chr3:52188851 WDR51A 0.83 7.45 0.37 7.69e-13 Macrophage inflammatory protein 1b levels; LIHC cis rs7520050 0.966 rs4660317 chr1:46326226 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs34779708 0.966 rs17499247 chr10:35426755 A/G cg03585969 chr10:35415529 CREM 0.85 12.94 0.57 1.93e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10097731 0.808 rs80141261 chr8:82034453 T/C cg25230327 chr8:82042993 NA -0.52 -6.89 -0.35 2.73e-11 Serum total protein level; LIHC trans rs1814175 0.708 rs10839464 chr11:49981386 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs10256972 0.900 rs7812072 chr7:1053862 A/G cg16145915 chr7:1198662 ZFAND2A -0.3 -7.21 -0.36 3.69e-12 Longevity;Endometriosis; LIHC trans rs1814175 0.618 rs1851843 chr11:50021846 T/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs6450176 0.625 rs3822499 chr5:53289459 C/G ch.5.1024479R chr5:53302184 ARL15 -0.89 -16.49 -0.67 2.23e-45 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs4820294 0.646 rs9622675 chr22:38053665 G/T cg00142150 chr22:38071001 LGALS1 0.44 7.5 0.38 5.41e-13 Fat distribution (HIV); LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg06873352 chr17:61820015 STRADA 0.69 11.33 0.52 1.72e-25 Prudent dietary pattern; LIHC cis rs7539624 0.588 rs10916602 chr1:223897425 G/A cg07395969 chr1:223900822 CAPN2 0.49 5.82 0.3 1.38e-8 Schizophrenia; LIHC cis rs6570726 0.818 rs399516 chr6:145810849 C/A cg23711669 chr6:146136114 FBXO30 0.57 10.16 0.48 2.35e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs7726839 0.574 rs72707007 chr5:661856 T/C cg09021430 chr5:549028 NA -0.42 -8.48 -0.42 6.8e-16 Obesity-related traits; LIHC cis rs7829975 0.711 rs12682352 chr8:8646246 A/G cg06636001 chr8:8085503 FLJ10661 0.44 6.99 0.35 1.44e-11 Mood instability; LIHC cis rs9911578 1.000 rs304292 chr17:56824123 G/A cg05425664 chr17:57184151 TRIM37 -0.57 -8.5 -0.42 5.75e-16 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.967 rs2965827 chr16:89457350 A/C cg08822215 chr16:89438651 ANKRD11 0.39 6.21 0.32 1.56e-9 Multiple myeloma (IgH translocation); LIHC cis rs7927771 0.524 rs7123952 chr11:47852057 T/C cg20307385 chr11:47447363 PSMC3 0.72 10.82 0.5 1.19e-23 Subjective well-being; LIHC cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg02290350 chr8:58132656 NA 0.48 8.98 0.44 1.92e-17 Developmental language disorder (linguistic errors); LIHC trans rs7226229 0.950 rs2291037 chr17:20924523 C/T cg04305134 chr10:75173374 ANXA7 -0.43 -6.35 -0.32 6.67e-10 Blood trace element (Se levels); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17105206 chr16:67211972 KIAA0895L -0.36 -6.13 -0.31 2.39e-9 Immature fraction of reticulocytes; LIHC trans rs11098499 0.863 rs6853998 chr4:120475860 C/A cg25214090 chr10:38739885 LOC399744 0.59 9.36 0.45 1.08e-18 Corneal astigmatism; LIHC cis rs9393692 0.967 rs6456712 chr6:26302573 A/C cg00631329 chr6:26305371 NA -0.51 -8.05 -0.4 1.38e-14 Educational attainment; LIHC cis rs898097 0.783 rs11650335 chr17:80835111 A/G cg15369054 chr17:80825471 TBCD 0.43 6.09 0.31 3.05e-9 Breast cancer; LIHC trans rs3960554 0.800 rs112463197 chr7:75622912 C/T cg19862616 chr7:65841803 NCRNA00174 0.57 7.58 0.38 3.26e-13 Eotaxin levels; LIHC cis rs7238033 0.624 rs11877062 chr18:43307246 C/T cg20610511 chr18:43302872 SLC14A1 0.4 6.78 0.34 5.21e-11 Bladder cancer; LIHC cis rs72781680 0.898 rs116113042 chr2:23960194 G/T cg08917208 chr2:24149416 ATAD2B 0.83 7.63 0.38 2.42e-13 Lymphocyte counts; LIHC cis rs1707322 1.000 rs4489497 chr1:46438698 C/T cg03146154 chr1:46216737 IPP 0.48 7.86 0.39 5.02e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs826838 1.000 rs11168505 chr12:38939057 A/T cg26384229 chr12:38710491 ALG10B -0.93 -12.98 -0.57 1.35e-31 Heart rate; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22293416 chr8:109493386 TTC35 -0.41 -6.25 -0.32 1.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836950 0.501 rs2836980 chr21:40687618 G/T cg11890956 chr21:40555474 PSMG1 -0.44 -7.02 -0.36 1.18e-11 Menarche (age at onset); LIHC cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg25894440 chr7:65020034 NA -0.53 -6.04 -0.31 4.05e-9 Diabetic kidney disease; LIHC trans rs17685 0.712 rs6954569 chr7:75738885 T/A cg19862616 chr7:65841803 NCRNA00174 0.91 18.79 0.71 1.31e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1904096 0.506 rs13434570 chr4:95168019 T/C cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.24 -0.45 2.76e-18 Type 2 diabetes; LIHC cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg11062466 chr8:58055876 NA 0.39 5.8 0.3 1.54e-8 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.522 rs1208684 chr10:38093936 G/A cg17830980 chr10:43048298 ZNF37B -0.43 -8.38 -0.41 1.43e-15 Extrinsic epigenetic age acceleration; LIHC cis rs1816752 0.746 rs9511270 chr13:25018680 C/T cg22771759 chr13:24902376 NA 0.31 6.46 0.33 3.52e-10 Obesity-related traits; LIHC cis rs1005277 0.579 rs2474568 chr10:38383147 A/T cg00409905 chr10:38381863 ZNF37A -0.62 -10.81 -0.5 1.23e-23 Extrinsic epigenetic age acceleration; LIHC cis rs35146811 0.555 rs2527898 chr7:99534030 C/G cg19636519 chr7:99541626 NA 0.31 6.01 0.31 4.67e-9 Coronary artery disease; LIHC cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.89 -10.67 -0.5 3.79e-23 Platelet count; LIHC cis rs7772486 0.846 rs9403767 chr6:146402386 G/T cg23711669 chr6:146136114 FBXO30 0.64 10.79 0.5 1.51e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs748404 0.631 rs4296223 chr15:43645246 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.86 0.43 4.31e-17 Lung cancer; LIHC cis rs2228479 0.702 rs11076620 chr16:89831520 A/T cg04013166 chr16:89971882 TCF25 0.52 6.46 0.33 3.55e-10 Skin colour saturation; LIHC cis rs10197940 0.578 rs2444264 chr2:152310928 G/T cg06191203 chr2:152266755 RIF1 0.39 6.65 0.34 1.18e-10 Lung cancer; LIHC trans rs1814175 0.817 rs10769613 chr11:49769692 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.17 -0.78 4.61e-72 Height; LIHC trans rs801193 0.935 rs3800820 chr7:66147178 C/T cg26939375 chr7:64535504 NA -0.42 -6.77 -0.34 5.73e-11 Aortic root size; LIHC cis rs12477438 0.765 rs28648058 chr2:99696417 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.55 -0.38 4.12e-13 Chronic sinus infection; LIHC cis rs6930083 0.713 rs1321308 chr6:36638691 A/C cg08179530 chr6:36648295 CDKN1A -0.77 -12.68 -0.57 1.79e-30 Coronary artery disease; LIHC trans rs12478296 1.000 rs6743297 chr2:243013814 A/G cg01596870 chr19:55963115 NA -0.66 -9.36 -0.45 1.1e-18 Obesity-related traits; LIHC cis rs7089973 0.604 rs10885620 chr10:116630048 A/T cg03647239 chr10:116582469 FAM160B1 0.46 6.58 0.34 1.77e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs933688 1.000 rs11948075 chr5:90680579 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.69 0.73 3.11e-58 Smoking behavior; LIHC cis rs950169 0.922 rs6603022 chr15:84830170 T/C cg17507749 chr15:85114479 UBE2QP1 -0.73 -8.8 -0.43 6.71e-17 Schizophrenia; LIHC cis rs16944613 0.510 rs4932353 chr15:91145838 T/C cg26821196 chr15:91095069 CRTC3 0.33 6.09 0.31 2.98e-9 Colorectal cancer; LIHC cis rs2629540 0.806 rs10901812 chr10:126419384 A/G cg08799069 chr10:126477246 METTL10 -0.44 -7.02 -0.36 1.16e-11 Cocaine dependence; LIHC trans rs9926296 0.572 rs2079671 chr16:89884981 T/C cg13698153 chr12:118541722 VSIG10 0.65 7.23 0.36 3.2e-12 Vitiligo; LIHC trans rs208520 0.690 rs207112 chr6:66792092 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs4319547 0.586 rs7956480 chr12:122817507 A/G cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.27 -0.37 2.46e-12 Body mass index; LIHC cis rs3849570 0.922 rs3772895 chr3:81769493 A/G cg07356753 chr3:81810745 GBE1 -0.63 -10.34 -0.49 5.49e-22 Waist circumference;Body mass index; LIHC cis rs3008870 0.755 rs10749766 chr1:67376921 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.64 10.81 0.5 1.28e-23 Lymphocyte percentage of white cells; LIHC cis rs769267 1.000 rs2074090 chr19:19449686 G/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -9.87 -0.47 2.26e-20 Tonsillectomy; LIHC cis rs9427116 0.532 rs9426828 chr1:154591489 G/A cg17218026 chr1:154582156 ADAR 0.36 7.11 0.36 6.83e-12 Blood protein levels; LIHC trans rs783540 0.900 rs55924160 chr15:83282196 C/T cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.11 -0.31 2.78e-9 Schizophrenia; LIHC cis rs7208859 0.623 rs6505207 chr17:29076571 T/C cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1814175 0.817 rs4405313 chr11:50013636 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs9322817 0.902 rs4336470 chr6:105180785 C/T cg02098413 chr6:105308735 HACE1 -0.39 -6.52 -0.33 2.48e-10 Thyroid stimulating hormone; LIHC cis rs8141529 1.000 rs8141529 chr22:29269692 A/G cg15103426 chr22:29168792 CCDC117 0.43 6.78 0.34 5.32e-11 Lymphocyte counts; LIHC cis rs67311347 1.000 rs4974017 chr3:40473519 C/T cg24209194 chr3:40518798 ZNF619 0.46 6.84 0.35 3.57e-11 Renal cell carcinoma; LIHC cis rs3768617 0.510 rs10911243 chr1:183075415 G/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.93 0.51 4.56e-24 Fuchs's corneal dystrophy; LIHC cis rs17253792 0.822 rs75999534 chr14:56036413 A/T cg01858014 chr14:56050164 KTN1 -0.72 -7.0 -0.35 1.36e-11 Putamen volume; LIHC cis rs2153535 0.580 rs1932279 chr6:8473653 T/C cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg26939375 chr7:64535504 NA -0.47 -7.04 -0.36 1.08e-11 Calcium levels; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.69 0.62 3.3e-38 Prudent dietary pattern; LIHC cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs12744310 1.000 rs12744310 chr1:41773502 C/T cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2412488 1.000 rs6827269 chr4:54320617 C/T cg22241045 chr4:54363911 LNX1 -0.45 -7.04 -0.36 1.09e-11 DNA methylation (variation); LIHC cis rs16828019 0.852 rs2268678 chr1:41511053 G/A cg03387723 chr1:41708464 SCMH1 -0.41 -6.47 -0.33 3.37e-10 Intelligence (multi-trait analysis); LIHC cis rs929354 0.739 rs12533082 chr7:157014172 T/A cg16102536 chr7:156981717 UBE3C 0.37 6.14 0.31 2.32e-9 Body mass index; LIHC cis rs9325144 0.560 rs7304568 chr12:38632408 G/A cg26384229 chr12:38710491 ALG10B -0.49 -7.44 -0.37 7.98e-13 Morning vs. evening chronotype; LIHC cis rs3820068 0.603 rs6429768 chr1:15963531 G/A cg17385448 chr1:15911702 AGMAT 0.33 5.8 0.3 1.53e-8 Systolic blood pressure; LIHC cis rs4665809 1.000 rs4665823 chr2:26312723 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.99 -0.44 1.69e-17 Gut microbiome composition (summer); LIHC cis rs12477438 0.765 rs6737257 chr2:99683330 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs8050755 0.536 rs78160478 chr16:2107322 G/T cg04515572 chr16:2107413 TSC2 -0.85 -6.17 -0.32 1.91e-9 Major depressive disorder; LIHC cis rs6964587 1.000 rs7791138 chr7:91686789 A/G cg17063962 chr7:91808500 NA 1.03 20.76 0.75 1.64e-62 Breast cancer; LIHC cis rs6960043 0.875 rs2215382 chr7:15055010 C/G cg19272540 chr7:15055459 NA 0.25 7.05 0.36 9.73e-12 Type 2 diabetes; LIHC cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg11644478 chr21:40555479 PSMG1 0.77 9.68 0.46 9.34e-20 Cognitive function; LIHC cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg15691649 chr6:25882328 NA 0.83 11.35 0.52 1.43e-25 Blood metabolite levels; LIHC cis rs941408 1.000 rs1736181 chr19:2797703 C/T cg02580895 chr19:2754563 NA -0.41 -6.09 -0.31 3e-9 Total cholesterol levels; LIHC cis rs780094 0.544 rs780108 chr2:27684957 T/C cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.82 -0.3 1.35e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17059624 chr11:85358760 TMEM126A 0.47 7.34 0.37 1.61e-12 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18502334 chr7:4681577 NA -0.44 -6.63 -0.34 1.28e-10 Cognitive function; LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs9443189 0.723 rs2748947 chr6:76437921 C/T cg01950844 chr6:76311363 SENP6 -0.51 -6.54 -0.33 2.28e-10 Prostate cancer; LIHC cis rs9381040 0.655 rs6939989 chr6:41020205 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.87 -0.35 3.06e-11 Alzheimer's disease (late onset); LIHC cis rs12135062 1.000 rs12135062 chr1:3103312 A/C cg21609526 chr1:3105151 PRDM16 0.27 6.12 0.31 2.54e-9 Migraine; LIHC trans rs61931739 0.500 rs7955247 chr12:34126580 G/A cg26384229 chr12:38710491 ALG10B 0.52 7.11 0.36 6.81e-12 Morning vs. evening chronotype; LIHC cis rs365132 0.902 rs353489 chr5:176461974 T/C cg16309518 chr5:176445507 NA -0.58 -11.32 -0.52 1.93e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs7131987 0.650 rs67146951 chr12:29450553 C/A cg00204748 chr12:29376779 FAR2 0.39 7.24 0.36 3.03e-12 QT interval; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg27432699 chr2:27873401 GPN1 -0.5 -7.27 -0.37 2.44e-12 Total body bone mineral density; LIHC cis rs12530845 0.943 rs58577912 chr7:135329269 T/G cg23117316 chr7:135346802 PL-5283 -0.35 -5.82 -0.3 1.38e-8 Red blood cell traits; LIHC cis rs644799 0.511 rs1016030 chr11:95472693 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.77 11.86 0.54 1.98e-27 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg24675658 chr1:53192096 ZYG11B 0.64 10.32 0.49 6.29e-22 Monocyte count; LIHC cis rs151997 0.925 rs27287 chr5:50195567 C/A cg06027927 chr5:50259733 NA 0.57 7.65 0.38 2.05e-13 Callous-unemotional behaviour; LIHC cis rs6138458 1.000 rs6106984 chr20:24977006 T/C cg26195577 chr20:24973756 C20orf3 1.2 16.23 0.66 2.61e-44 Blood protein levels; LIHC cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg16822855 chr3:40428330 ENTPD3 0.35 6.35 0.32 6.9e-10 Renal cell carcinoma; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg13374389 chr22:30821762 MTP18 -0.51 -6.44 -0.33 3.98e-10 Hip circumference; LIHC cis rs2228479 0.850 rs11645240 chr16:89837326 T/C cg00800038 chr16:89945340 TCF25 -0.61 -9.15 -0.44 5.27e-18 Skin colour saturation; LIHC trans rs304172 0.793 rs304170 chr3:62780639 A/G cg07662676 chr19:39322573 ECH1 0.84 6.06 0.31 3.64e-9 IgG glycosylation; LIHC cis rs477692 0.673 rs511361 chr10:131365052 C/T cg05714579 chr10:131428358 MGMT 0.43 6.85 0.35 3.41e-11 Response to temozolomide; LIHC cis rs17685 0.753 rs2286830 chr7:75693963 C/T cg01364799 chr7:75623366 TMEM120A 0.52 7.88 0.39 4.29e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7187994 0.848 rs12934432 chr16:84770913 T/A cg07647771 chr16:84786436 USP10 -0.34 -6.3 -0.32 9.21e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs9596863 0.898 rs9568924 chr13:54360952 T/G ch.13.53330881F chr13:54432880 NA 0.45 6.03 0.31 4.21e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs10089 1.000 rs3792866 chr5:127479900 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.53 6.68 0.34 9.73e-11 Ileal carcinoids; LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg06873352 chr17:61820015 STRADA 0.56 8.51 0.42 5.66e-16 Height; LIHC cis rs4891159 0.655 rs890393 chr18:74102435 G/T cg24786174 chr18:74118243 ZNF516 -0.72 -13.19 -0.58 2.21e-32 Longevity; LIHC cis rs12478296 1.000 rs73007129 chr2:243000555 T/C cg06360820 chr2:242988706 NA -0.96 -12.35 -0.56 3.11e-29 Obesity-related traits; LIHC cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 13.16 0.58 2.73e-32 Alzheimer's disease; LIHC cis rs6596100 0.538 rs67519234 chr5:132199359 C/A cg02081065 chr5:132209139 LEAP2 0.29 6.3 0.32 9.39e-10 Breast cancer; LIHC cis rs11718455 0.883 rs4682926 chr3:44006170 C/T cg08738300 chr3:44038990 NA 0.51 8.86 0.43 4.47e-17 Coronary artery disease; LIHC cis rs12530845 0.623 rs73721681 chr7:135361917 A/G cg23117316 chr7:135346802 PL-5283 -0.43 -6.18 -0.32 1.84e-9 Red blood cell traits; LIHC cis rs4803468 1.000 rs3810175 chr19:41904396 C/T cg09537434 chr19:41945824 ATP5SL 1.0 21.08 0.75 8.69e-64 Height; LIHC cis rs7666738 0.570 rs11097612 chr4:99079772 T/C cg05340658 chr4:99064831 C4orf37 0.65 11.74 0.54 5.61e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg24642844 chr7:1081250 C7orf50 -0.91 -8.98 -0.44 1.81e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2304069 0.779 rs245080 chr5:149354805 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.72 -9.8 -0.47 3.95e-20 HIV-1 control; LIHC cis rs4423214 1.000 rs909217 chr11:71146577 G/A cg24826892 chr11:71159390 DHCR7 0.49 6.31 0.32 8.5e-10 Vitamin D levels; LIHC cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg11890956 chr21:40555474 PSMG1 1.06 15.32 0.64 1.03e-40 Cognitive function; LIHC cis rs9733 0.596 rs12063547 chr1:150674053 G/T cg15448220 chr1:150897856 SETDB1 -0.4 -6.31 -0.32 8.73e-10 Tonsillectomy; LIHC trans rs9929218 0.953 rs9927329 chr16:68750331 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.19 -0.45 3.78e-18 Colorectal cancer; LIHC cis rs4589502 0.614 rs17273637 chr15:67193084 C/T cg09911534 chr15:67153556 NA -0.47 -5.82 -0.3 1.32e-8 Lung cancer (smoking interaction); LIHC cis rs4631830 0.863 rs10826125 chr10:51530505 G/A cg20129853 chr10:51489980 NA -0.41 -8.96 -0.44 2.13e-17 Prostate-specific antigen levels; LIHC cis rs7843479 0.965 rs11784535 chr8:21857787 G/A cg17168535 chr8:21777572 XPO7 0.39 6.26 0.32 1.18e-9 Mean corpuscular volume; LIHC cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg22528358 chr1:107598549 PRMT6 -0.64 -10.76 -0.5 1.82e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg06873352 chr17:61820015 STRADA 0.73 12.79 0.57 6.79e-31 Prudent dietary pattern; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg21561701 chr13:114193150 TMCO3 -0.36 -6.05 -0.31 3.74e-9 Pain; LIHC cis rs3750965 0.919 rs12280942 chr11:68859683 A/G cg01403660 chr11:68851641 TPCN2 -0.44 -7.15 -0.36 5.17e-12 Hair color; LIHC cis rs6977660 1.000 rs2107403 chr7:19819025 G/C cg07541023 chr7:19748670 TWISTNB 0.37 5.82 0.3 1.36e-8 Thyroid stimulating hormone; LIHC cis rs6762 0.642 rs28692469 chr11:839675 T/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.78 -0.47 4.28e-20 Mean platelet volume; LIHC cis rs3736485 0.966 rs2124877 chr15:51906275 A/G cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.57e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7572733 0.555 rs1435569 chr2:198718667 G/C cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs9534288 0.659 rs7996394 chr13:46653503 A/C cg15192986 chr13:46630673 CPB2 -0.45 -6.45 -0.33 3.8e-10 Blood protein levels; LIHC cis rs6782228 0.606 rs7650156 chr3:128361555 T/A cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs3857067 0.806 rs28408270 chr4:95114572 G/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.6 -0.38 2.95e-13 QT interval; LIHC trans rs8002861 0.935 rs1811464 chr13:44469290 T/G cg17145862 chr1:211918768 LPGAT1 0.67 13.3 0.58 8.01e-33 Leprosy; LIHC cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs9868809 0.505 rs9882549 chr3:48749358 C/T cg07636037 chr3:49044803 WDR6 -0.7 -7.35 -0.37 1.49e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs7296418 0.738 rs1568428 chr12:123738876 A/G cg00376283 chr12:123451042 ABCB9 -0.63 -10.32 -0.49 6.44e-22 Platelet count; LIHC cis rs11122272 0.735 rs2486740 chr1:231517552 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs28829049 0.570 rs12060125 chr1:19391108 A/G cg13935437 chr1:19600673 AKR7L 0.31 5.73 0.3 2.15e-8 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs9326248 0.773 rs1060211 chr11:117039797 G/A cg11861562 chr11:117069780 TAGLN 0.36 5.73 0.3 2.15e-8 Blood protein levels; LIHC cis rs240764 0.578 rs6925065 chr6:101178856 C/T cg09795085 chr6:101329169 ASCC3 0.41 6.13 0.31 2.36e-9 Neuroticism; LIHC cis rs875971 1.000 rs709595 chr7:65817333 G/C cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs2976388 0.578 rs13263987 chr8:143827387 A/C cg06565975 chr8:143823917 SLURP1 -0.45 -8.31 -0.41 2.26e-15 Urinary tract infection frequency; LIHC cis rs2625529 0.824 rs16953769 chr15:72463325 G/A cg16672083 chr15:72433130 SENP8 -0.3 -5.72 -0.3 2.34e-8 Red blood cell count; LIHC cis rs79387448 0.745 rs74560841 chr2:103149210 G/A cg09003973 chr2:102972529 NA 0.96 7.82 0.39 6.63e-14 Gut microbiota (bacterial taxa); LIHC cis rs13064411 0.735 rs13098166 chr3:113210038 A/G cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs9394841 0.692 rs35085306 chr6:41856002 A/G cg17623882 chr6:41773611 USP49 -0.44 -5.86 -0.3 1.09e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg13206674 chr6:150067644 NUP43 0.46 9.13 0.44 5.92e-18 Lung cancer; LIHC cis rs17685 0.753 rs1574107 chr7:75685047 A/C cg01364799 chr7:75623366 TMEM120A -0.52 -7.83 -0.39 6.2e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2274273 1.000 rs61508494 chr14:55587297 T/C cg04306507 chr14:55594613 LGALS3 0.33 6.16 0.32 2e-9 Protein biomarker; LIHC cis rs2153535 0.601 rs2143353 chr6:8530111 T/G cg07606381 chr6:8435919 SLC35B3 0.79 11.5 0.53 4.42e-26 Motion sickness; LIHC cis rs7937682 0.889 rs487985 chr11:111517908 G/A cg09085632 chr11:111637200 PPP2R1B -1.03 -12.38 -0.56 2.44e-29 Primary sclerosing cholangitis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02744793 chr10:35378717 CUL2 0.46 6.11 0.31 2.66e-9 Lung function (FEV1/FVC); LIHC cis rs11958404 0.932 rs72816564 chr5:157427484 T/C cg05962755 chr5:157440814 NA 1.06 11.94 0.54 1.02e-27 IgG glycosylation; LIHC cis rs780096 0.527 rs11127044 chr2:27740404 C/G cg05484376 chr2:27715224 FNDC4 0.4 6.68 0.34 9.57e-11 Total body bone mineral density; LIHC trans rs875971 0.545 rs1638724 chr7:66040481 A/G cg26939375 chr7:64535504 NA -0.39 -6.2 -0.32 1.66e-9 Aortic root size; LIHC cis rs2204008 0.807 rs12816136 chr12:38456037 A/G cg13010199 chr12:38710504 ALG10B -0.43 -5.99 -0.31 5.22e-9 Bladder cancer; LIHC cis rs34172651 0.517 rs11647120 chr16:24819806 A/G cg00152838 chr16:24741724 TNRC6A -0.53 -6.38 -0.33 5.77e-10 Intelligence (multi-trait analysis); LIHC cis rs17253792 0.915 rs77161327 chr14:56178565 A/G cg01858014 chr14:56050164 KTN1 -0.75 -7.41 -0.37 9.7e-13 Putamen volume; LIHC cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg27170947 chr2:26402098 FAM59B -0.67 -8.39 -0.41 1.26e-15 Gut microbiome composition (summer); LIHC cis rs1997103 0.863 rs4480062 chr7:55401299 T/C cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7044106 0.762 rs10760112 chr9:123467570 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 8.03 0.4 1.63e-14 Hip circumference adjusted for BMI; LIHC trans rs1005277 0.579 rs2472174 chr10:38375382 A/G cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9486715 0.867 rs1127175 chr6:96999725 C/T cg06623918 chr6:96969491 KIAA0776 -0.82 -13.88 -0.6 4.75e-35 Headache; LIHC cis rs1046896 1.000 rs1046917 chr17:80685655 A/G cg00809820 chr17:80708513 TBCD;FN3K -0.33 -5.74 -0.3 2.08e-8 Glycated hemoglobin levels; LIHC cis rs4665809 1.000 rs1550381 chr2:26266946 A/G cg27170947 chr2:26402098 FAM59B -0.68 -8.33 -0.41 1.97e-15 Gut microbiome composition (summer); LIHC cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg11644478 chr21:40555479 PSMG1 0.85 10.76 0.5 1.87e-23 Cognitive function; LIHC cis rs10504229 0.679 rs16921683 chr8:58053270 T/C cg20607798 chr8:58055168 NA 0.45 6.11 0.31 2.7e-9 Developmental language disorder (linguistic errors); LIHC cis rs9911578 0.933 rs2531725 chr17:56517962 G/A cg12560992 chr17:57184187 TRIM37 0.94 16.62 0.67 6.65e-46 Intelligence (multi-trait analysis); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg03621406 chr19:9930365 FBXL12 -0.48 -6.09 -0.31 2.98e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.51 -9.44 -0.45 5.89e-19 Prudent dietary pattern; LIHC cis rs5753618 0.561 rs2283879 chr22:31638448 G/A cg22777020 chr22:31556080 RNF185 -0.55 -6.31 -0.32 8.59e-10 Colorectal cancer; LIHC cis rs9733 0.519 rs11587444 chr1:150722844 A/G cg18016565 chr1:150552671 MCL1 0.58 11.19 0.52 5.39e-25 Tonsillectomy; LIHC cis rs7178375 1.000 rs12907055 chr15:31204294 C/G cg19680485 chr15:31195859 MTMR15 -0.53 -5.92 -0.3 7.78e-9 Hypertriglyceridemia; LIHC cis rs35892873 0.920 rs3890851 chr3:126093700 G/T cg15490784 chr3:126061950 KLF15 0.44 6.51 0.33 2.69e-10 Male-pattern baldness; LIHC cis rs8062405 1.000 rs62036621 chr16:28833299 C/A cg07451762 chr16:28383216 NA 0.32 6.14 0.31 2.33e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4763879 0.739 rs2114871 chr12:9829438 A/T cg26689682 chr12:9723402 NA -0.36 -5.92 -0.3 8e-9 Type 1 diabetes; LIHC cis rs875971 0.756 rs2901210 chr7:66017505 G/A cg18252515 chr7:66147081 NA 0.46 6.8 0.35 4.67e-11 Aortic root size; LIHC cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg03517284 chr6:25882590 NA -0.65 -9.31 -0.45 1.57e-18 Blood metabolite levels; LIHC cis rs9916302 0.571 rs28799952 chr17:37533056 C/T cg07936489 chr17:37558343 FBXL20 0.86 12.17 0.55 1.45e-28 Glomerular filtration rate (creatinine); LIHC cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg19318889 chr4:1322082 MAEA 0.55 8.78 0.43 7.72e-17 Longevity; LIHC cis rs72781680 0.799 rs2712084 chr2:24003051 A/G cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.07e-9 Lymphocyte counts; LIHC cis rs12135062 0.901 rs2651928 chr1:3101722 C/T cg25382214 chr1:3105252 PRDM16 -0.28 -6.2 -0.32 1.62e-9 Migraine; LIHC cis rs2274273 0.870 rs7153645 chr14:55771518 C/G cg01864836 chr14:55583639 NA -0.37 -6.63 -0.34 1.34e-10 Protein biomarker; LIHC cis rs9309711 0.922 rs13385119 chr2:3484521 G/A cg10845886 chr2:3471009 TTC15 -0.61 -11.67 -0.53 1.02e-26 Neurofibrillary tangles; LIHC cis rs2637266 1.000 rs2579749 chr10:78332105 T/C cg18941641 chr10:78392320 NA 0.28 5.91 0.3 8.17e-9 Pulmonary function; LIHC cis rs7129220 0.588 rs7105321 chr11:10111339 T/C cg01453529 chr11:10209919 SBF2 -0.39 -6.93 -0.35 2.13e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs2019216 0.564 rs907707 chr17:21910083 G/C cg22648282 chr17:21454238 C17orf51 -0.44 -7.43 -0.37 8.68e-13 Pelvic organ prolapse; LIHC cis rs6121246 0.909 rs6060960 chr20:30394517 G/T cg13852791 chr20:30311386 BCL2L1 -0.8 -8.31 -0.41 2.33e-15 Mean corpuscular hemoglobin; LIHC cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.98e-12 Developmental language disorder (linguistic errors); LIHC cis rs7666738 0.606 rs6839946 chr4:99076132 A/C cg05340658 chr4:99064831 C4orf37 0.65 11.65 0.53 1.18e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs7264396 0.563 rs78084033 chr20:34219990 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.55 -6.57 -0.33 1.84e-10 Total cholesterol levels; LIHC cis rs951366 0.873 rs823118 chr1:205723572 C/T cg14159672 chr1:205819179 PM20D1 0.32 5.81 0.3 1.42e-8 Menarche (age at onset); LIHC cis rs2842992 0.715 rs2277073 chr6:160182749 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.05 0.55 4.18e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs2839186 0.732 rs8131458 chr21:47694712 G/A cg12379764 chr21:47803548 PCNT -0.6 -8.53 -0.42 4.77e-16 Testicular germ cell tumor; LIHC cis rs7520050 0.966 rs785464 chr1:46523089 T/C cg03146154 chr1:46216737 IPP -0.36 -5.94 -0.31 7.06e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2637266 1.000 rs12251862 chr10:78367929 A/G cg18941641 chr10:78392320 NA 0.31 6.76 0.34 6.15e-11 Pulmonary function; LIHC cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg13047869 chr3:10149882 C3orf24 0.53 6.3 0.32 9.19e-10 Alzheimer's disease; LIHC cis rs1568889 1.000 rs61889046 chr11:28297024 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 7.06 0.36 9.06e-12 Bipolar disorder; LIHC cis rs735396 1.000 rs1169311 chr12:121440731 C/T cg25281562 chr12:121454272 C12orf43 0.33 5.74 0.3 2.08e-8 N-glycan levels; LIHC cis rs1538970 0.962 rs2298018 chr1:45813441 T/C cg24296786 chr1:45957014 TESK2 -0.5 -7.48 -0.38 6.21e-13 Platelet count; LIHC cis rs7100689 0.646 rs1340374 chr10:82129114 C/T cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs644799 0.526 rs693792 chr11:95622200 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.62 9.67 0.46 1.02e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12478296 0.792 rs6740738 chr2:243007368 A/C cg06360820 chr2:242988706 NA -0.8 -12.17 -0.55 1.5e-28 Obesity-related traits; LIHC cis rs1292048 1 rs1292048 chr17:57955071 A/G cg13753209 chr17:57696993 CLTC 0.38 5.83 0.3 1.3e-8 Red cell distribution width; LIHC cis rs7772486 0.875 rs7739371 chr6:146424353 C/G cg23711669 chr6:146136114 FBXO30 0.64 10.98 0.51 3.21e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs1801251 1.000 rs6717841 chr2:233590255 C/T cg08000102 chr2:233561755 GIGYF2 0.77 11.51 0.53 3.96e-26 Coronary artery disease; LIHC cis rs713477 1.000 rs10134905 chr14:55911792 G/A cg13175173 chr14:55914753 NA -0.36 -8.26 -0.41 3.34e-15 Pediatric bone mineral content (femoral neck); LIHC trans rs9858542 1.000 rs13085791 chr3:49721798 C/A cg21659725 chr3:3221576 CRBN -0.55 -6.17 -0.32 1.94e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6456156 0.586 rs12527827 chr6:167469271 C/T cg12798992 chr6:167411361 FGFR1OP 0.44 6.85 0.35 3.44e-11 Primary biliary cholangitis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17937102 chr1:165667565 ALDH9A1 0.57 7.45 0.37 7.85e-13 Lung function (FEV1/FVC); LIHC cis rs7613875 0.580 rs12634780 chr3:50043341 A/T cg21467203 chr3:49911342 NA 0.52 9.46 0.46 5.29e-19 Body mass index; LIHC cis rs17376456 0.569 rs10076965 chr5:93094972 G/A cg25358565 chr5:93447407 FAM172A 0.81 7.78 0.39 8.84e-14 Diabetic retinopathy; LIHC cis rs9640161 0.830 rs3757423 chr7:150067714 A/G cg10018233 chr7:150070692 REPIN1 -0.69 -13.08 -0.58 5.77e-32 Blood protein levels;Circulating chemerin levels; LIHC cis rs79149102 0.579 rs58645417 chr15:75325858 T/G cg15902774 chr15:75289873 SCAMP5 0.44 6.52 0.33 2.47e-10 Lung cancer; LIHC cis rs7551222 0.614 rs4951386 chr1:204454547 A/G cg20240347 chr1:204465584 NA -0.32 -6.71 -0.34 7.98e-11 Schizophrenia; LIHC cis rs12295403 0.964 rs61886869 chr11:18688508 C/T cg09887367 chr11:18690185 NA -0.41 -6.82 -0.35 4.1e-11 Ovarian reserve; LIHC cis rs7264396 0.790 rs761826 chr20:34194243 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.58 -9.65 -0.46 1.23e-19 Total cholesterol levels; LIHC cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 8.93 0.43 2.68e-17 Platelet count; LIHC cis rs1707322 0.691 rs11211175 chr1:46220884 C/G cg03146154 chr1:46216737 IPP 0.59 10.17 0.48 2.07e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12586317 0.547 rs3759548 chr14:35450333 C/T cg05294307 chr14:35346193 BAZ1A -0.51 -7.31 -0.37 1.89e-12 Psoriasis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07355551 chr20:2489285 ZNF343 0.46 6.66 0.34 1.11e-10 Pancreatic cancer; LIHC cis rs2115536 0.967 rs4778734 chr15:80210851 A/G cg11839771 chr15:80205821 ST20 -0.31 -6.46 -0.33 3.55e-10 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg00661245 chr8:11660924 FDFT1 0.47 6.24 0.32 1.27e-9 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs7937682 1.000 rs10502147 chr11:111569931 G/A cg09085632 chr11:111637200 PPP2R1B 1.09 13.26 0.58 1.12e-32 Primary sclerosing cholangitis; LIHC cis rs9527 0.615 rs3897401 chr10:104696379 T/C cg15744005 chr10:104629667 AS3MT -0.29 -5.73 -0.3 2.16e-8 Arsenic metabolism; LIHC cis rs1003719 0.715 rs9980353 chr21:38558812 T/G cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.76 -0.5 1.81e-23 Eye color traits; LIHC cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17401966 1.000 rs17411502 chr1:10431158 T/C cg15208524 chr1:10270712 KIF1B 0.43 6.16 0.32 2.04e-9 Hepatocellular carcinoma; LIHC cis rs751728 0.931 rs2013365 chr6:33763688 A/C cg25922239 chr6:33757077 LEMD2 0.43 6.96 0.35 1.71e-11 Crohn's disease; LIHC cis rs875971 0.862 rs4368860 chr7:65608482 C/G cg11764359 chr7:65958608 NA -0.82 -13.79 -0.6 1.02e-34 Aortic root size; LIHC cis rs11969893 0.850 rs9404058 chr6:101323078 T/C cg12253828 chr6:101329408 ASCC3 1.07 13.85 0.6 6.24e-35 Economic and political preferences (immigration/crime); LIHC cis rs9341808 0.587 rs3805859 chr6:81048946 C/A cg08355045 chr6:80787529 NA 0.32 6.62 0.34 1.43e-10 Sitting height ratio; LIHC cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg19318889 chr4:1322082 MAEA 0.47 6.51 0.33 2.69e-10 Obesity-related traits; LIHC trans rs116095464 0.558 rs113796397 chr5:246503 A/G cg00938859 chr5:1591904 SDHAP3 0.56 6.84 0.35 3.75e-11 Breast cancer; LIHC cis rs9818758 0.607 rs9837237 chr3:49215583 G/T cg07636037 chr3:49044803 WDR6 -0.77 -7.6 -0.38 2.88e-13 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs61990749 0.597 rs10142722 chr14:78275549 A/T cg23188588 chr14:78226832 SNW1;C14orf178 0.56 9.16 0.44 4.84e-18 Fibroblast growth factor basic levels; LIHC cis rs2760061 0.603 rs697762 chr1:228192410 G/A cg02753203 chr1:228287806 NA 0.61 10.36 0.49 4.65e-22 Diastolic blood pressure; LIHC cis rs17253792 0.822 rs7150841 chr14:56088986 T/C cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs6951245 0.580 rs77101766 chr7:1122438 A/G cg22907277 chr7:1156413 C7orf50 0.91 8.63 0.42 2.32e-16 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9911578 0.692 rs411988 chr17:56709034 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.53 7.36 0.37 1.35e-12 Intelligence (multi-trait analysis); LIHC trans rs208520 0.690 rs6929762 chr6:66709277 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.74 8.64 0.42 2.15e-16 Exhaled nitric oxide output; LIHC cis rs2455799 0.553 rs12495958 chr3:15941439 G/T cg12698662 chr3:15914712 MIR563 -0.34 -6.41 -0.33 4.94e-10 Mean platelet volume; LIHC cis rs7927592 0.913 rs12285993 chr11:68302538 A/G cg01657329 chr11:68192670 LRP5 -0.47 -6.08 -0.31 3.22e-9 Total body bone mineral density; LIHC cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg09904177 chr6:26538194 HMGN4 0.57 11.2 0.52 5.05e-25 Intelligence (multi-trait analysis); LIHC cis rs9303401 0.659 rs7224276 chr17:56897827 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.19 0.55 1.22e-28 Cognitive test performance; LIHC cis rs55882075 0.514 rs11249655 chr5:179111290 C/T cg14593053 chr5:179126677 CANX 0.39 6.77 0.34 5.73e-11 Monocyte percentage of white cells; LIHC cis rs875971 0.660 rs801217 chr7:66010577 C/T cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs1008375 0.898 rs2079892 chr4:17577163 G/A cg02297831 chr4:17616191 MED28 0.48 7.28 0.37 2.31e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7927771 0.894 rs12798346 chr11:47583121 C/T cg18512352 chr11:47633146 NA -0.25 -6.01 -0.31 4.84e-9 Subjective well-being; LIHC cis rs225245 0.791 rs6505492 chr17:34026597 C/T cg05299278 chr17:33885742 SLFN14 0.23 6.2 0.32 1.66e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg06634786 chr22:41940651 POLR3H -0.81 -9.01 -0.44 1.51e-17 Vitiligo; LIHC cis rs4819052 0.765 rs2838868 chr21:46714641 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.69 -9.32 -0.45 1.48e-18 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg11301795 chr4:187892539 NA -0.26 -6.99 -0.35 1.44e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 1.000 rs6750681 chr2:26329677 C/T cg04944784 chr2:26401820 FAM59B -0.65 -8.37 -0.41 1.53e-15 Gut microbiome composition (summer); LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg22963979 chr7:1858916 MAD1L1 -0.4 -6.54 -0.33 2.23e-10 Bipolar disorder and schizophrenia; LIHC cis rs7833790 0.660 rs1451995 chr8:82746123 G/C cg02079420 chr8:82753780 SNX16 -0.37 -6.79 -0.34 5.06e-11 Diastolic blood pressure; LIHC cis rs1728785 1.000 rs698717 chr16:68560199 A/G cg02972257 chr16:68554789 NA -0.56 -6.42 -0.33 4.6e-10 Ulcerative colitis; LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg18538332 chr22:24372958 LOC391322 0.58 8.15 0.4 6.95e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs853679 0.517 rs9393891 chr6:28079160 C/T cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Depression; LIHC trans rs2749592 0.531 rs1208559 chr10:38221370 T/C cg27523141 chr10:43048294 ZNF37B -0.36 -6.34 -0.32 7.43e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg10295955 chr4:187884368 NA -0.97 -23.17 -0.78 4.65e-72 Lobe attachment (rater-scored or self-reported); LIHC cis rs1997103 1.000 rs10249105 chr7:55412405 A/G cg17469321 chr7:55412551 NA -0.44 -6.66 -0.34 1.1e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9309473 1.000 rs7583255 chr2:73797996 T/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs4820294 0.516 rs12627943 chr22:38096334 C/G cg00292662 chr22:38071168 LGALS1 0.64 8.39 0.41 1.33e-15 Fat distribution (HIV); LIHC cis rs1211375 0.607 rs1203978 chr16:257211 A/C cg00126636 chr16:237282 NA 0.41 6.92 0.35 2.18e-11 Hematology traits;Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs8067545 0.641 rs397969 chr17:19804247 T/C cg13482628 chr17:19912719 NA 0.38 6.1 0.31 2.86e-9 Schizophrenia; LIHC trans rs334353 0.785 rs334363 chr9:101928702 A/C cg06788856 chr17:1821969 NA -0.33 -6.13 -0.31 2.45e-9 Age-related macular degeneration; LIHC trans rs1814175 0.708 rs10839464 chr11:49981386 T/C cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC trans rs6952808 0.723 rs11765550 chr7:2027324 G/A cg04565464 chr8:145669602 NFKBIL2 0.4 6.64 0.34 1.23e-10 Bipolar disorder and schizophrenia; LIHC cis rs7618501 1.000 rs3811696 chr3:49761605 C/T cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs992157 0.932 rs56109829 chr2:219149740 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.81 13.05 0.58 7.16e-32 Colorectal cancer; LIHC cis rs2455799 0.573 rs2455829 chr3:15746937 G/A cg12698662 chr3:15914712 MIR563 -0.38 -7.09 -0.36 7.65e-12 Mean platelet volume; LIHC trans rs2262909 0.962 rs73021832 chr19:22316144 G/C cg17074339 chr11:11642133 GALNTL4 0.47 7.32 0.37 1.8e-12 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs1046896 0.562 rs9912684 chr17:80873067 C/T cg22027946 chr17:80790580 TBCD;ZNF750 0.43 6.09 0.31 3.02e-9 Glycated hemoglobin levels; LIHC cis rs2243480 0.901 rs778687 chr7:65835819 G/A cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC cis rs3806843 1.000 rs4151682 chr5:140201264 C/T cg19875535 chr5:140030758 IK 0.36 5.82 0.3 1.36e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2760061 0.819 rs708111 chr1:228191365 G/A cg02753203 chr1:228287806 NA 0.48 7.85 0.39 5.36e-14 Diastolic blood pressure; LIHC cis rs17608059 0.524 rs9897978 chr17:13900256 G/T cg27005118 chr17:13972210 COX10 0.44 7.34 0.37 1.58e-12 Temperament; LIHC cis rs67311347 1.000 rs6795475 chr3:40489281 A/G cg18306943 chr3:40428807 ENTPD3 0.34 6.07 0.31 3.31e-9 Renal cell carcinoma; LIHC cis rs116095464 0.614 rs28736753 chr5:274081 G/A cg22857025 chr5:266934 NA -1.47 -18.07 -0.7 9.95e-52 Breast cancer; LIHC cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg10802521 chr3:52805072 NEK4 -0.45 -7.38 -0.37 1.24e-12 Bipolar disorder; LIHC cis rs61990749 0.597 rs2112136 chr14:78248952 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.61 9.99 0.48 8.92e-21 Fibroblast growth factor basic levels; LIHC cis rs6694270 0.529 rs4076925 chr1:19113026 C/T cg26220594 chr1:19110978 NA 0.32 5.8 0.3 1.5e-8 Drug-induced liver injury (nitrofurantoin); LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg06873352 chr17:61820015 STRADA 0.74 13.21 0.58 1.74e-32 Prudent dietary pattern; LIHC cis rs2075671 0.903 rs62483570 chr7:100300649 C/T cg20848291 chr7:100343083 ZAN -0.48 -6.97 -0.35 1.68e-11 Other erythrocyte phenotypes; LIHC trans rs4714291 1.000 rs847751 chr6:40035607 A/G cg02267698 chr19:7991119 CTXN1 0.4 6.32 0.32 8.15e-10 Strep throat; LIHC cis rs8141529 0.719 rs5762880 chr22:29287816 T/G cg15103426 chr22:29168792 CCDC117 0.58 9.52 0.46 3.32e-19 Lymphocyte counts; LIHC cis rs853679 0.517 rs9368558 chr6:28133306 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs754466 0.580 rs17516020 chr10:79538734 C/T cg17075019 chr10:79541650 NA -0.68 -7.39 -0.37 1.1e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg19774624 chr17:42201019 HDAC5 -0.82 -12.74 -0.57 1.07e-30 Total body bone mineral density; LIHC cis rs12477438 0.520 rs2516829 chr2:99773201 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 13.38 0.59 3.85e-33 Chronic sinus infection; LIHC cis rs918629 0.798 rs3777163 chr5:95293316 C/G cg10483112 chr5:95245456 ELL2 -0.35 -6.05 -0.31 3.91e-9 IgG glycosylation; LIHC cis rs17685 0.712 rs10952842 chr7:75780413 G/A cg01364799 chr7:75623366 TMEM120A -0.41 -6.12 -0.31 2.5e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7408868 1.000 rs7245814 chr19:15274503 A/G cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC cis rs11758351 1.000 rs77957229 chr6:26185226 A/G cg03785755 chr6:26196794 NA 0.52 5.73 0.3 2.16e-8 Gout;Renal underexcretion gout; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13489987 chr14:67292488 GPHN 0.26 6.24 0.32 1.32e-9 Cognitive function; LIHC cis rs904251 0.523 rs1757191 chr6:37482871 C/T cg08126542 chr6:37504118 NA -0.36 -6.2 -0.32 1.58e-9 Cognitive performance; LIHC cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg07061783 chr6:25882402 NA -0.44 -6.3 -0.32 9.05e-10 Blood metabolite levels; LIHC cis rs8072100 0.748 rs9908016 chr17:45551361 G/A cg08085267 chr17:45401833 C17orf57 -0.44 -6.5 -0.33 2.82e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs6058796 0.786 rs28789846 chr20:31275545 G/A cg02600331 chr11:130417168 NA 0.37 8.02 0.4 1.64e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg02359409 chr6:42947317 PEX6 -0.47 -6.66 -0.34 1.07e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3749237 0.595 rs7643845 chr3:49530711 A/G cg06212747 chr3:49208901 KLHDC8B 0.46 6.01 0.31 4.66e-9 Resting heart rate; LIHC cis rs7312933 0.669 rs7974476 chr12:42542484 C/A cg17420585 chr12:42539391 GXYLT1 -0.36 -5.75 -0.3 1.94e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs875971 0.545 rs17138156 chr7:65714695 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.38 7.63 0.38 2.3e-13 Aortic root size; LIHC cis rs11792861 0.781 rs874864 chr9:111728718 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 9.19 0.44 3.97e-18 Menarche (age at onset); LIHC cis rs10751667 0.643 rs10902257 chr11:973577 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.83 -0.63 8.92e-39 Alzheimer's disease (late onset); LIHC cis rs2153535 0.601 rs7775274 chr6:8530303 A/G cg21535247 chr6:8435926 SLC35B3 0.65 8.63 0.42 2.43e-16 Motion sickness; LIHC cis rs7129556 0.520 rs4945178 chr11:77248911 T/C cg03570279 chr11:77446074 RSF1 -0.34 -6.31 -0.32 8.85e-10 Weight loss (gastric bypass surgery); LIHC cis rs1448094 0.511 rs11117042 chr12:86207547 G/T cg02569458 chr12:86230093 RASSF9 0.46 6.1 0.31 2.8e-9 Major depressive disorder; LIHC cis rs9522267 0.535 rs9522290 chr13:112233130 A/G cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs3768617 0.510 rs12091137 chr1:183075732 A/G ch.1.3577855R chr1:183094577 LAMC1 0.63 11.34 0.52 1.65e-25 Fuchs's corneal dystrophy; LIHC cis rs7572733 0.534 rs700688 chr2:198723833 A/G cg00792783 chr2:198669748 PLCL1 -0.48 -7.24 -0.36 3.02e-12 Dermatomyositis; LIHC cis rs6120849 0.754 rs1885116 chr20:33600560 A/G cg24642439 chr20:33292090 TP53INP2 0.65 7.2 0.36 3.91e-12 Protein C levels; LIHC cis rs17152411 0.652 rs1046373 chr10:126674689 A/C cg07906193 chr10:126599966 NA -0.3 -5.91 -0.3 8.39e-9 Height; LIHC cis rs6674176 0.628 rs4660758 chr1:44424879 A/C cg12908607 chr1:44402522 ARTN -0.48 -8.2 -0.41 4.77e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs929354 0.772 rs6969244 chr7:157004012 A/G cg16102536 chr7:156981717 UBE3C 0.35 5.84 0.3 1.21e-8 Body mass index; LIHC cis rs2050392 0.624 rs303450 chr10:30725337 C/A cg25182066 chr10:30743637 MAP3K8 -0.61 -9.73 -0.47 6.42e-20 Inflammatory bowel disease; LIHC cis rs10484885 0.877 rs17735389 chr6:90323139 G/T cg13799429 chr6:90582589 CASP8AP2 -0.6 -5.92 -0.3 7.92e-9 QRS interval (sulfonylurea treatment interaction); LIHC cis rs875971 0.862 rs6460290 chr7:65809106 G/A cg18876405 chr7:65276391 NA -0.35 -6.35 -0.32 6.9e-10 Aortic root size; LIHC cis rs2569991 0.636 rs361223 chr3:12922526 T/C cg22481960 chr3:13008800 IQSEC1 -0.4 -6.91 -0.35 2.44e-11 Periodontitis (DPAL); LIHC cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg22520471 chr17:61851767 DDX42;CCDC47 -0.72 -12.19 -0.55 1.24e-28 Prudent dietary pattern; LIHC cis rs13191362 1.000 rs73008453 chr6:163013384 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.89 0.3 9.07e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8013055 0.846 rs10151805 chr14:105974781 T/C cg19700328 chr14:106028568 NA -0.35 -7.61 -0.38 2.64e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.6 8.82 0.43 5.9e-17 Lymphocyte counts; LIHC cis rs76419734 0.510 rs6820671 chr4:106613821 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.77 9.09 0.44 8.43e-18 Post bronchodilator FEV1; LIHC cis rs9911578 0.741 rs2611776 chr17:56819636 G/T cg05425664 chr17:57184151 TRIM37 -0.57 -8.5 -0.42 5.75e-16 Intelligence (multi-trait analysis); LIHC trans rs3794271 0.706 rs9971816 chr12:20826911 C/T cg05664664 chr10:75173569 ANXA7 -0.41 -6.03 -0.31 4.15e-9 Response to TNF-alpha inhibitors in rheumatoid arthritis; LIHC cis rs10779751 1.000 rs7549109 chr1:11278813 C/G cg08854313 chr1:11322531 MTOR -0.87 -15.74 -0.65 2.35e-42 Body mass index; LIHC cis rs992157 0.560 rs6738394 chr2:219110625 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.75 -12.34 -0.56 3.42e-29 Colorectal cancer; LIHC cis rs7487075 0.619 rs4076247 chr12:46833450 A/C cg23829395 chr12:46796953 NA 0.34 6.05 0.31 3.81e-9 Itch intensity from mosquito bite; LIHC cis rs10420951 0.579 rs78036311 chr19:18606369 G/T cg10790698 chr19:18539756 SSBP4 -0.41 -5.72 -0.3 2.35e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs539096 0.500 rs2367804 chr1:44314266 C/T cg12908607 chr1:44402522 ARTN -0.47 -7.94 -0.39 2.96e-14 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1023500 0.529 rs133375 chr22:42466509 C/G cg04733989 chr22:42467013 NAGA 0.66 9.65 0.46 1.22e-19 Schizophrenia; LIHC cis rs7833986 0.501 rs17815934 chr8:57038395 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.65 0.42 2.09e-16 Height; LIHC cis rs950169 0.544 rs62021193 chr15:85170583 C/G cg03959625 chr15:84868606 LOC388152 0.43 6.07 0.31 3.43e-9 Schizophrenia; LIHC cis rs875971 1.000 rs6970030 chr7:65968679 T/C cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.54e-9 Aortic root size; LIHC cis rs4780401 0.609 rs35649585 chr16:11813899 G/A cg01061890 chr16:11836724 TXNDC11 -0.65 -10.33 -0.49 5.81e-22 Rheumatoid arthritis; LIHC cis rs2635047 0.904 rs2635046 chr18:44728429 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.44 5.97 0.31 6e-9 Educational attainment; LIHC cis rs6500602 0.702 rs2058812 chr16:4524443 C/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.85 0.3 1.13e-8 Schizophrenia; LIHC cis rs7520050 0.807 rs12025621 chr1:46228391 G/A cg03146154 chr1:46216737 IPP -0.48 -8.01 -0.4 1.83e-14 Red blood cell count;Reticulocyte count; LIHC cis rs10463316 0.894 rs12652733 chr5:150753999 G/A cg03212797 chr5:150827313 SLC36A1 -0.42 -6.26 -0.32 1.18e-9 Metabolite levels (Pyroglutamine); LIHC cis rs651907 0.557 rs11710533 chr3:101351472 G/A cg11279151 chr3:101281821 RG9MTD1 -0.41 -6.16 -0.32 2.01e-9 Colorectal cancer; LIHC cis rs679087 0.612 rs7970465 chr12:29905251 C/T cg14258853 chr12:29935411 TMTC1 -0.45 -6.61 -0.34 1.45e-10 Schizophrenia; LIHC cis rs2073300 1.000 rs12625804 chr20:23441981 G/A cg16736954 chr20:23401023 NAPB 0.53 5.91 0.3 8.15e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs16866061 1.000 rs72974222 chr2:225424143 C/T cg12698349 chr2:225449008 CUL3 0.8 13.96 0.6 2.22e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs539514 0.587 rs9530466 chr13:76323774 T/C cg04757411 chr13:76259545 LMO7 -0.42 -7.14 -0.36 5.68e-12 Type 1 diabetes; LIHC cis rs9325144 0.560 rs6582561 chr12:38666821 G/A cg26384229 chr12:38710491 ALG10B -0.59 -8.02 -0.4 1.65e-14 Morning vs. evening chronotype; LIHC cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg06453172 chr10:134556979 INPP5A -0.64 -8.83 -0.43 5.65e-17 Migraine; LIHC cis rs11745587 0.539 rs6897597 chr5:131743465 C/T cg24060327 chr5:131705240 SLC22A5 -0.46 -5.77 -0.3 1.79e-8 Asthma; LIHC cis rs79149102 0.579 rs12591175 chr15:75356073 C/T cg17294928 chr15:75287854 SCAMP5 -0.5 -6.29 -0.32 9.46e-10 Lung cancer; LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg27432699 chr2:27873401 GPN1 -0.54 -7.79 -0.39 8.1e-14 Menopause (age at onset); LIHC cis rs9918079 0.560 rs7438356 chr4:15624770 C/T cg18470593 chr4:15471377 CC2D2A -0.39 -6.0 -0.31 4.95e-9 Obesity-related traits; LIHC cis rs8078723 0.763 rs4433838 chr17:38143532 C/T cg17467752 chr17:38218738 THRA -0.59 -10.13 -0.48 2.93e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9300255 0.506 rs61388686 chr12:123810873 G/A cg05973401 chr12:123451056 ABCB9 0.41 6.3 0.32 8.98e-10 Neutrophil percentage of white cells; LIHC cis rs208520 0.802 rs1342959 chr6:66883329 A/G cg07460842 chr6:66804631 NA -0.76 -8.34 -0.41 1.89e-15 Exhaled nitric oxide output; LIHC cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg00149659 chr3:10157352 C3orf10 0.69 7.22 0.36 3.42e-12 Alzheimer's disease; LIHC cis rs2455799 0.613 rs2470548 chr3:15737689 G/A cg12698662 chr3:15914712 MIR563 -0.35 -6.52 -0.33 2.6e-10 Mean platelet volume; LIHC cis rs801193 1.000 rs4717310 chr7:66161007 C/T cg14393609 chr7:65229607 NA 0.38 5.92 0.31 7.71e-9 Aortic root size; LIHC cis rs11098699 1.000 rs1031134 chr4:124194477 G/A cg09941581 chr4:124220074 SPATA5 0.3 5.72 0.3 2.29e-8 Mosquito bite size; LIHC cis rs7617773 0.743 rs6804986 chr3:48363595 A/G cg11946769 chr3:48343235 NME6 0.91 11.93 0.54 1.11e-27 Coronary artery disease; LIHC cis rs12368653 0.557 rs903067 chr12:58011857 G/A cg12615879 chr12:58013172 SLC26A10 -0.32 -6.21 -0.32 1.52e-9 Multiple sclerosis; LIHC cis rs3204270 0.684 rs62080212 chr17:79642500 G/A cg18367735 chr17:79674897 NA 0.72 8.05 0.4 1.37e-14 Dental caries; LIHC cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg00750074 chr16:89608354 SPG7 -0.52 -8.5 -0.42 5.76e-16 Multiple myeloma (IgH translocation); LIHC cis rs1552244 0.554 rs6762702 chr3:10055789 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.75 0.39 1.05e-13 Alzheimer's disease; LIHC cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.74 0.39 1.14e-13 Bipolar disorder; LIHC cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg06453172 chr10:134556979 INPP5A -0.65 -8.12 -0.4 8.75e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg12373951 chr3:133503437 NA 0.46 7.73 0.39 1.22e-13 Iron status biomarkers; LIHC cis rs858239 0.601 rs6461693 chr7:23160133 A/G cg23682824 chr7:23144976 KLHL7 -0.42 -6.35 -0.32 6.89e-10 Cerebrospinal fluid biomarker levels; LIHC trans rs916888 0.773 rs199451 chr17:44801784 G/A cg12297030 chr17:43662878 NA -0.64 -6.12 -0.31 2.57e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs1814175 0.645 rs847632 chr11:49926097 C/T cg03929089 chr4:120376271 NA -0.84 -15.86 -0.65 7.39e-43 Height; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg10081115 chr2:190686883 PMS1 0.41 6.04 0.31 3.98e-9 Bilirubin levels; LIHC cis rs2777491 0.540 rs7164684 chr15:41705008 G/T cg18705301 chr15:41695430 NDUFAF1 -1.23 -18.77 -0.71 1.58e-54 Ulcerative colitis; LIHC cis rs198813 0.611 rs198823 chr6:26122933 G/T cg18357526 chr6:26021779 HIST1H4A -0.48 -6.82 -0.35 4.24e-11 Intelligence (multi-trait analysis); LIHC cis rs798554 1.000 rs798536 chr7:2766383 G/A cg19717773 chr7:2847554 GNA12 -0.41 -6.45 -0.33 3.77e-10 Height; LIHC cis rs1395 0.626 rs72817537 chr2:27497549 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -5.8 -0.3 1.55e-8 Blood metabolite levels; LIHC cis rs882732 0.576 rs12895360 chr14:95038922 T/C cg14866387 chr14:95027382 SERPINA4 -0.37 -5.82 -0.3 1.37e-8 Blood protein levels; LIHC cis rs2067615 0.560 rs4964485 chr12:107121952 A/G cg15890332 chr12:107067104 RFX4 0.27 6.42 0.33 4.49e-10 Heart rate; LIHC cis rs12477438 0.798 rs12477754 chr2:99628073 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.55 -0.53 2.75e-26 Chronic sinus infection; LIHC cis rs6951245 0.872 rs57068908 chr7:1060084 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -6.1 -0.31 2.86e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1008375 0.966 rs11733730 chr4:17625209 G/C cg02297831 chr4:17616191 MED28 0.5 7.83 0.39 6.24e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6964587 1.000 rs34548928 chr7:91668365 G/A cg17063962 chr7:91808500 NA 1.02 19.65 0.73 4.62e-58 Breast cancer; LIHC cis rs763121 0.853 rs8140617 chr22:38970439 A/G cg21395723 chr22:39101663 GTPBP1 -0.42 -6.5 -0.33 2.9e-10 Menopause (age at onset); LIHC cis rs4555082 0.834 rs2816607 chr14:105718385 A/T cg06808227 chr14:105710500 BRF1 -0.49 -6.05 -0.31 3.79e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs6952808 0.931 rs7810038 chr7:1894116 T/C cg02951883 chr7:2050386 MAD1L1 -0.53 -7.82 -0.39 6.83e-14 Bipolar disorder and schizophrenia; LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg02475777 chr4:1388615 CRIPAK 0.53 7.96 0.4 2.6e-14 Longevity; LIHC cis rs6121246 0.954 rs6089093 chr20:30421459 C/T cg13852791 chr20:30311386 BCL2L1 0.86 8.88 0.43 3.94e-17 Mean corpuscular hemoglobin; LIHC cis rs6782228 0.527 rs2811491 chr3:128353950 C/A cg16766828 chr3:128327626 NA -0.39 -6.14 -0.32 2.27e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7027203 0.828 rs3996239 chr9:96611290 T/A cg14396892 chr9:96623032 NA -0.32 -6.22 -0.32 1.43e-9 DNA methylation (variation); LIHC cis rs4776059 0.550 rs8036979 chr15:52947995 A/T cg22715398 chr15:52968154 KIAA1370 0.4 5.74 0.3 2.08e-8 Schizophrenia; LIHC cis rs2073499 1.000 rs57319506 chr3:50285677 T/C cg03645007 chr3:50255295 SLC38A3 0.52 6.35 0.32 6.97e-10 Schizophrenia; LIHC cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg12292205 chr6:26970375 C6orf41 -0.48 -8.19 -0.4 5.31e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg18252515 chr7:66147081 NA -1.24 -16.13 -0.66 6.34e-44 Diabetic kidney disease; LIHC cis rs7605378 0.528 rs281787 chr2:200784238 C/T cg17644776 chr2:200775616 C2orf69 -0.41 -5.9 -0.3 8.77e-9 Osteoporosis; LIHC cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg05368731 chr17:41323189 NBR1 0.72 12.37 0.56 2.77e-29 Menopause (age at onset); LIHC cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg19626725 chr5:178986131 RUFY1 0.38 5.8 0.3 1.5e-8 Lung cancer; LIHC cis rs116095464 0.558 rs62344345 chr5:257420 C/T cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC trans rs4322600 0.963 rs1450711 chr14:88288660 T/C cg16008221 chr8:17823628 PCM1 -0.43 -6.32 -0.32 8.16e-10 Breast cancer; LIHC cis rs365132 0.875 rs2962842 chr5:176338955 A/G cg16309518 chr5:176445507 NA -0.52 -9.64 -0.46 1.33e-19 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs8141529 0.584 rs58004020 chr22:29257050 A/T cg02153584 chr22:29168773 CCDC117 0.55 8.65 0.42 2.04e-16 Lymphocyte counts; LIHC cis rs1403694 0.734 rs266723 chr3:186447047 A/C cg12454167 chr3:186435060 KNG1 0.26 6.42 0.33 4.53e-10 Blood protein levels; LIHC cis rs7123876 0.504 rs1157343 chr11:72429141 A/G cg03713592 chr11:72463424 ARAP1 -0.51 -6.16 -0.32 2.07e-9 Body mass index; LIHC cis rs7264396 0.690 rs2425178 chr20:34446395 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.83 -0.51 1.07e-23 Total cholesterol levels; LIHC cis rs35883536 0.647 rs10875317 chr1:101045438 G/T cg14515779 chr1:101123966 NA 0.5 7.13 0.36 6.03e-12 Monocyte count; LIHC cis rs12477438 0.572 rs10170063 chr2:99655639 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs11190604 0.725 rs9420796 chr10:102323092 G/C cg07080220 chr10:102295463 HIF1AN 0.52 7.18 0.36 4.39e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 10.1 0.48 3.53e-21 Platelet count; LIHC cis rs1005277 0.579 rs1740737 chr10:38499365 G/T cg25427524 chr10:38739819 LOC399744 -0.72 -13.99 -0.6 1.75e-35 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.67 0.57 2.05e-30 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13837895 chr19:50145301 SCAF1 0.41 6.22 0.32 1.41e-9 Pancreatic cancer; LIHC cis rs12701220 0.655 rs6955290 chr7:1151066 A/G cg18765753 chr7:1198926 ZFAND2A 0.45 6.44 0.33 4.06e-10 Bronchopulmonary dysplasia; LIHC cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg18404041 chr3:52824283 ITIH1 -0.58 -9.66 -0.46 1.08e-19 Bipolar disorder; LIHC cis rs1865760 0.622 rs10946807 chr6:26079638 T/C cg17691542 chr6:26056736 HIST1H1C 0.61 8.08 0.4 1.12e-14 Height; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg17269277 chr4:1796142 FGFR3 0.55 6.67 0.34 1.03e-10 Hepatitis; LIHC cis rs12497850 0.931 rs4974085 chr3:48924900 C/T cg07636037 chr3:49044803 WDR6 0.93 17.52 0.69 1.72e-49 Parkinson's disease; LIHC cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg09323728 chr8:95962352 TP53INP1 -0.3 -6.36 -0.33 6.49e-10 Type 2 diabetes; LIHC cis rs3784262 0.967 rs4646612 chr15:58265077 C/T cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.29 -0.32 9.54e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs5769765 0.862 rs9616380 chr22:50312225 T/C cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs9918079 0.542 rs12499412 chr4:15602252 G/C cg21329975 chr4:15471214 CC2D2A 0.41 6.23 0.32 1.38e-9 Obesity-related traits; LIHC cis rs10792665 0.649 rs9971403 chr11:82761790 G/T cg24227371 chr11:82718527 RAB30 -0.37 -8.76 -0.43 9.11e-17 Obesity-related traits; LIHC cis rs2404602 0.692 rs35999717 chr15:77193367 G/C cg03037974 chr15:76606532 NA 0.73 14.3 0.61 1.08e-36 Blood metabolite levels; LIHC cis rs16944613 0.510 rs7165476 chr15:91151948 C/T cg26821196 chr15:91095069 CRTC3 0.33 6.06 0.31 3.66e-9 Colorectal cancer; LIHC trans rs2727020 0.786 rs10839263 chr11:49354462 A/G cg03929089 chr4:120376271 NA -0.65 -9.66 -0.46 1.09e-19 Coronary artery disease; LIHC cis rs8180040 0.726 rs4078466 chr3:47126543 C/T cg16586182 chr3:47516702 SCAP -0.52 -9.49 -0.46 3.98e-19 Colorectal cancer; LIHC trans rs6934970 0.932 rs6914487 chr6:113124193 T/A cg02462569 chr6:150064036 NUP43 -0.46 -6.09 -0.31 3.1e-9 Bipolar disorder (body mass index interaction); LIHC cis rs422249 0.512 rs174561 chr11:61582708 T/C cg27386326 chr11:61587980 NA 0.71 14.77 0.62 1.62e-38 Trans fatty acid levels; LIHC cis rs9918079 0.560 rs12651550 chr4:15641018 G/C cg24225360 chr4:15471699 CC2D2A -0.39 -6.23 -0.32 1.4e-9 Obesity-related traits; LIHC cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg21433313 chr16:3507492 NAT15 -0.46 -7.66 -0.38 1.96e-13 Tuberculosis; LIHC cis rs8141529 0.748 rs2064261 chr22:29287730 C/T cg15103426 chr22:29168792 CCDC117 0.58 9.54 0.46 2.69e-19 Lymphocyte counts; LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs10883723 0.810 rs3818470 chr10:104263675 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.11 0.58 4.13e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs769267 0.930 rs4808959 chr19:19572108 T/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.97 0.31 6.01e-9 Tonsillectomy; LIHC cis rs6596100 0.538 rs113848378 chr5:132192372 T/C cg02081065 chr5:132209139 LEAP2 0.29 6.3 0.32 9.39e-10 Breast cancer; LIHC cis rs897984 0.568 rs8063565 chr16:30883965 G/C cg02466173 chr16:30829666 NA 0.44 6.64 0.34 1.2e-10 Dementia with Lewy bodies; LIHC cis rs7075426 0.669 rs3858279 chr10:88257602 A/G cg07322936 chr10:88137208 NA 0.48 6.25 0.32 1.23e-9 Migraine without aura; LIHC cis rs6461049 0.765 rs10224497 chr7:2149967 A/G cg04267008 chr7:1944627 MAD1L1 -0.54 -8.37 -0.41 1.47e-15 Schizophrenia; LIHC cis rs5770917 1.000 rs3213446 chr22:51015674 C/T cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.5 -6.5 -0.33 2.82e-10 Narcolepsy; LIHC cis rs9457247 0.663 rs2237277 chr6:167442107 G/A cg23791538 chr6:167370224 RNASET2 -0.61 -10.55 -0.5 1.06e-22 Crohn's disease; LIHC trans rs10761482 0.500 rs1938535 chr10:62273900 A/G cg14898824 chr12:64851143 TBK1 -0.33 -6.22 -0.32 1.44e-9 Schizophrenia; LIHC cis rs2625529 0.824 rs10518979 chr15:72268986 A/G cg16672083 chr15:72433130 SENP8 -0.3 -5.77 -0.3 1.82e-8 Red blood cell count; LIHC cis rs9910055 0.571 rs10208 chr17:42300278 C/T cg19774624 chr17:42201019 HDAC5 -0.45 -6.32 -0.32 8.22e-10 Total body bone mineral density; LIHC cis rs611744 0.647 rs615233 chr8:109254262 C/T cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs801193 0.967 rs2707853 chr7:66214010 G/A cg00343986 chr7:65444356 GUSB 0.41 6.16 0.32 2.05e-9 Aortic root size; LIHC cis rs2153535 0.580 rs7753192 chr6:8482637 G/A cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs559928 0.606 rs11231710 chr11:63925743 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.75 7.3 0.37 1.97e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg25586305 chr2:234281690 DGKD 0.45 6.07 0.31 3.39e-9 Hepatitis; LIHC cis rs4803468 1.000 rs284657 chr19:41929915 G/C cg09537434 chr19:41945824 ATP5SL -1.02 -20.82 -0.75 9.24e-63 Height; LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg20607798 chr8:58055168 NA 0.62 7.92 0.39 3.38e-14 Developmental language disorder (linguistic errors); LIHC cis rs1707322 1.000 rs4073847 chr1:46463012 A/C cg03146154 chr1:46216737 IPP -0.48 -7.72 -0.39 1.26e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1395 0.744 rs4665962 chr2:27515105 A/G cg22903471 chr2:27725779 GCKR -0.43 -6.32 -0.32 7.98e-10 Blood metabolite levels; LIHC cis rs6545883 0.929 rs1209434 chr2:61672958 G/A cg15711740 chr2:61764176 XPO1 -0.43 -6.01 -0.31 4.72e-9 Tuberculosis; LIHC cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg10935138 chr17:73851978 WBP2 0.77 10.35 0.49 5.09e-22 Psoriasis; LIHC cis rs798554 0.523 rs1182197 chr7:2863289 A/C cg13628971 chr7:2884303 GNA12 0.41 6.31 0.32 8.64e-10 Height; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg11494091 chr17:61959527 GH2 0.45 8.32 0.41 2.12e-15 Prudent dietary pattern; LIHC cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg18252515 chr7:66147081 NA -0.94 -12.31 -0.55 4.48e-29 Diabetic kidney disease; LIHC cis rs6089584 0.566 rs6061401 chr20:60607482 G/A cg23262073 chr20:60523788 NA -0.29 -6.04 -0.31 4.08e-9 Body mass index; LIHC cis rs1055129 0.516 rs7218498 chr17:73931847 C/G cg10935138 chr17:73851978 WBP2 0.49 7.31 0.37 1.85e-12 White matter hyperintensity burden; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg10862723 chr17:47022239 SNF8 0.48 6.54 0.33 2.18e-10 Glycated hemoglobin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02186127 chr17:33914245 AP2B1 0.47 6.41 0.33 4.82e-10 Pancreatic cancer; LIHC cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg23835219 chr4:1244017 CTBP1;C4orf42 -0.4 -5.81 -0.3 1.44e-8 Longevity; LIHC cis rs1008375 1.000 rs6848360 chr4:17634442 G/T cg16339924 chr4:17578868 LAP3 0.44 6.13 0.31 2.38e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2404602 0.684 rs8037847 chr15:76856551 C/T cg03037974 chr15:76606532 NA -0.61 -10.3 -0.49 7.81e-22 Blood metabolite levels; LIHC cis rs4555082 0.756 rs76863138 chr14:105736379 C/T cg13114125 chr14:105738426 BRF1 -0.74 -9.67 -0.46 1.06e-19 Mean platelet volume;Platelet distribution width; LIHC cis rs2842992 0.672 rs4708845 chr6:160219601 T/G cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.95 0.44 2.28e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs1005277 0.579 rs1780139 chr10:38503018 C/T cg00409905 chr10:38381863 ZNF37A -0.54 -8.99 -0.44 1.67e-17 Extrinsic epigenetic age acceleration; LIHC cis rs11583043 0.874 rs6577222 chr1:101420502 C/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.18 0.44 4.07e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4891159 0.790 rs683306 chr18:74112473 C/G cg24786174 chr18:74118243 ZNF516 -0.79 -14.58 -0.62 8.85e-38 Longevity; LIHC cis rs28453840 1 rs28453840 chr2:136522941 G/A cg17750252 chr2:136567154 LCT 0.35 6.15 0.32 2.22e-9 Cholesterol, total; LIHC cis rs920590 0.721 rs920587 chr8:19663339 C/A cg03894339 chr8:19674705 INTS10 0.61 9.91 0.47 1.66e-20 Acute lymphoblastic leukemia (childhood); LIHC cis rs2710642 0.576 rs1386399 chr2:62871303 G/A cg17519650 chr2:63277830 OTX1 0.47 6.88 0.35 2.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs7188697 0.922 rs7186997 chr16:58603348 A/G cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC trans rs7227401 1.000 rs7227401 chr18:21938658 G/T cg25268537 chr17:72860402 FDXR 0.69 6.31 0.32 8.62e-10 Osteoporosis-related phenotypes; LIHC cis rs735860 0.687 rs2294852 chr6:53157214 C/G cg10236188 chr6:53219634 NA -0.43 -7.62 -0.38 2.6e-13 Glaucoma; LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.85 0.63 7.56e-39 Prudent dietary pattern; LIHC cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg19774624 chr17:42201019 HDAC5 0.8 12.07 0.55 3.43e-28 Total body bone mineral density; LIHC cis rs34172651 0.606 rs7194189 chr16:24703484 G/T cg00339695 chr16:24857497 SLC5A11 -0.48 -7.69 -0.38 1.62e-13 Intelligence (multi-trait analysis); LIHC cis rs2191566 0.960 rs8105571 chr19:44510341 C/T cg20607764 chr19:44506953 ZNF230 -0.41 -6.66 -0.34 1.1e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs12586317 0.513 rs11156871 chr14:35481196 G/A cg05294307 chr14:35346193 BAZ1A -0.49 -7.42 -0.37 9.63e-13 Psoriasis; LIHC cis rs3617 0.573 rs12638968 chr3:52919447 T/A cg11645453 chr3:52864694 ITIH4 -0.23 -6.05 -0.31 3.81e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs10751667 0.643 rs10902234 chr11:935578 A/G cg06064525 chr11:970664 AP2A2 -0.55 -14.97 -0.63 2.48e-39 Alzheimer's disease (late onset); LIHC cis rs10504229 0.610 rs7840469 chr8:58146992 C/T cg21724239 chr8:58056113 NA 0.49 6.7 0.34 8.63e-11 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06756557 chr10:90639746 STAMBPL1 0.45 6.87 0.35 3.11e-11 Cognitive function; LIHC cis rs12478296 0.515 rs13412492 chr2:243000583 T/G cg06360820 chr2:242988706 NA -0.74 -10.92 -0.51 5.18e-24 Obesity-related traits; LIHC cis rs2239815 0.515 rs5762848 chr22:29236308 A/G cg15103426 chr22:29168792 CCDC117 0.43 5.74 0.3 2.11e-8 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC cis rs10540 1.000 rs35231079 chr11:515224 G/A cg03352830 chr11:487213 PTDSS2 0.79 6.39 0.33 5.48e-10 Body mass index; LIHC cis rs7129220 0.660 rs6483969 chr11:10100734 G/A cg01453529 chr11:10209919 SBF2 -0.39 -6.97 -0.35 1.62e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs12791968 1.000 rs12791968 chr11:45001490 C/T cg11846598 chr11:44996168 LOC221122 0.44 7.81 0.39 7.25e-14 Inhibitory control; LIHC cis rs3845702 0.673 rs12468986 chr2:180862320 T/G cg01881094 chr2:180872142 CWC22 1.12 9.94 0.47 1.24e-20 Schizophrenia; LIHC trans rs10506458 1.000 rs1009539 chr12:63414655 A/G cg22491629 chr6:157744540 C6orf35 0.58 10.66 0.5 4.29e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs1355223 0.867 rs1869360 chr11:34698590 C/T cg11058730 chr11:34937778 PDHX;APIP -0.42 -5.84 -0.3 1.19e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7552404 1.000 rs7533888 chr1:76160449 A/C cg10523679 chr1:76189770 ACADM 0.66 9.11 0.44 7.16e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs796364 0.806 rs74724807 chr2:201005109 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.74 -8.22 -0.41 4.2e-15 Schizophrenia; LIHC cis rs80282103 0.867 rs3793781 chr10:1081293 G/T cg08668510 chr10:1095578 IDI1 0.74 7.55 0.38 4.07e-13 Glomerular filtration rate (creatinine); LIHC cis rs67478160 0.634 rs7141928 chr14:104219949 C/T cg01849466 chr14:104193079 ZFYVE21 -0.53 -9.17 -0.44 4.36e-18 Schizophrenia; LIHC cis rs910316 0.763 rs2080201 chr14:75629972 C/T cg11812906 chr14:75593930 NEK9 -0.73 -13.48 -0.59 1.66e-33 Height; LIHC trans rs11722228 0.522 rs73212808 chr4:10055439 G/C cg26043149 chr18:55253948 FECH 0.86 10.93 0.51 4.88e-24 Gout;Urate levels;Serum uric acid levels; LIHC cis rs7224737 1.000 rs11869069 chr17:40287101 C/G cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs12908161 0.959 rs3748376 chr15:85328352 C/T cg12863693 chr15:85201151 NMB 0.44 6.27 0.32 1.11e-9 Schizophrenia; LIHC cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg20607798 chr8:58055168 NA 0.49 6.23 0.32 1.34e-9 Developmental language disorder (linguistic errors); LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg17178900 chr1:205818956 PM20D1 0.74 10.89 0.51 6.79e-24 Menarche (age at onset); LIHC cis rs644148 0.730 rs2686766 chr19:44991595 T/G cg15540054 chr19:45004280 ZNF180 -0.74 -10.02 -0.48 7.03e-21 Personality dimensions; LIHC cis rs35110281 0.807 rs4818850 chr21:45028071 T/G cg04455712 chr21:45112962 RRP1B 0.46 7.92 0.39 3.28e-14 Mean corpuscular volume; LIHC cis rs12477438 0.520 rs6542870 chr2:99796638 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.66 0.65 4.89e-42 Chronic sinus infection; LIHC cis rs1348850 0.914 rs1975544 chr2:178465423 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.78 11.34 0.52 1.57e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4676482 0.541 rs17735402 chr3:39205176 C/T cg02254461 chr3:39195904 CSRNP1 0.73 6.91 0.35 2.34e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg05665937 chr4:1216051 CTBP1 0.45 6.32 0.32 8.06e-10 Obesity-related traits; LIHC cis rs9814567 0.806 rs4955526 chr3:134317337 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.78 -0.3 1.67e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4474465 1.000 rs12277701 chr11:78140726 A/T cg27205649 chr11:78285834 NARS2 -0.39 -5.82 -0.3 1.37e-8 Alzheimer's disease (survival time); LIHC cis rs7408868 1.000 rs7254735 chr19:15263385 A/G cg09752223 chr19:15281200 NOTCH3 -0.36 -5.83 -0.3 1.3e-8 Pulse pressure; LIHC cis rs61990749 0.597 rs1477262 chr14:78226653 G/A cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.77 -0.39 9.28e-14 Fibroblast growth factor basic levels; LIHC cis rs9303401 0.614 rs2240719 chr17:56582477 G/C cg25039879 chr17:56429692 SUPT4H1 0.74 8.29 0.41 2.71e-15 Cognitive test performance; LIHC cis rs9916302 0.904 rs634365 chr17:37436966 C/T cg00129232 chr17:37814104 STARD3 -0.39 -6.43 -0.33 4.36e-10 Glomerular filtration rate (creatinine); LIHC cis rs523522 0.962 rs12309824 chr12:120990582 A/C cg12219531 chr12:120966889 COQ5 0.67 13.31 0.58 7.46e-33 High light scatter reticulocyte count; LIHC cis rs12908161 1.000 rs35726233 chr15:85337800 C/T cg17507749 chr15:85114479 UBE2QP1 0.63 7.18 0.36 4.38e-12 Schizophrenia; LIHC cis rs4665809 0.590 rs13019536 chr2:26526978 C/A cg04944784 chr2:26401820 FAM59B -0.43 -5.74 -0.3 2.11e-8 Gut microbiome composition (summer); LIHC cis rs875971 1.000 rs2420591 chr7:65912381 T/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs7572733 0.515 rs11891555 chr2:198853540 G/T cg10820045 chr2:198174542 NA 0.47 7.21 0.36 3.53e-12 Dermatomyositis; LIHC cis rs422249 0.547 rs174537 chr11:61552680 G/T cg27386326 chr11:61587980 NA 0.7 14.72 0.62 2.45e-38 Trans fatty acid levels; LIHC cis rs116095464 0.558 rs56127718 chr5:270273 G/T cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC trans rs1005277 0.540 rs2145487 chr10:38010077 A/G cg17830980 chr10:43048298 ZNF37B -0.42 -8.12 -0.4 8.5e-15 Extrinsic epigenetic age acceleration; LIHC cis rs7578199 0.779 rs17387035 chr2:242394003 A/G cg19372975 chr2:242212901 HDLBP -0.55 -5.76 -0.3 1.86e-8 Chronic lymphocytic leukemia; LIHC cis rs2075671 0.903 rs11520986 chr7:100276994 A/G cg20848291 chr7:100343083 ZAN -0.46 -6.56 -0.33 1.98e-10 Other erythrocyte phenotypes; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg04456666 chr15:40615783 NA -0.47 -6.56 -0.33 1.97e-10 Alopecia areata; LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.98 -0.4 2.19e-14 Lymphocyte counts; LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg24846343 chr22:24311635 DDTL 0.6 10.65 0.5 4.52e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs80282103 0.571 rs56183119 chr10:1068370 C/T cg20335179 chr10:1068567 C10orf110;IDI2 -0.61 -6.85 -0.35 3.35e-11 Glomerular filtration rate (creatinine); LIHC cis rs611744 0.967 rs641721 chr8:109230140 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs9914988 0.832 rs12946132 chr17:27157362 T/C cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs1552244 0.882 rs56332224 chr3:10037321 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.06 -0.44 1.04e-17 Alzheimer's disease; LIHC cis rs9814567 1.000 rs11919350 chr3:134235970 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3008870 1.000 rs2755256 chr1:67471692 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.93 15.92 0.65 4.54e-43 Lymphocyte percentage of white cells; LIHC cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg13607699 chr17:42295918 UBTF -0.43 -6.9 -0.35 2.6e-11 Total body bone mineral density; LIHC cis rs79057730 0.528 rs6965219 chr7:821807 C/G cg06242242 chr7:766104 PRKAR1B;HEATR2 0.75 8.27 0.41 2.99e-15 Initial pursuit acceleration; LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.29 0.55 5.09e-29 Prudent dietary pattern; LIHC cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg12310025 chr6:25882481 NA -0.65 -9.31 -0.45 1.53e-18 Blood metabolite levels; LIHC cis rs6500602 0.653 rs3747579 chr16:4445327 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.42 -5.73 -0.3 2.16e-8 Schizophrenia; LIHC cis rs3768617 1.000 rs3768617 chr1:183092500 C/T ch.1.3577855R chr1:183094577 LAMC1 0.38 6.42 0.33 4.45e-10 Fuchs's corneal dystrophy; LIHC cis rs6448317 0.954 rs35276311 chr4:24923493 C/T cg21108841 chr4:24914750 CCDC149 -0.5 -6.24 -0.32 1.33e-9 Heschl's gyrus morphology; LIHC cis rs7829975 0.871 rs777709 chr8:8583872 T/C cg15556689 chr8:8085844 FLJ10661 -0.36 -5.77 -0.3 1.74e-8 Mood instability; LIHC cis rs17685 0.671 rs10274404 chr7:75706634 G/A cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.41e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6088580 0.524 rs6088570 chr20:33268295 T/C cg08999081 chr20:33150536 PIGU -0.43 -7.37 -0.37 1.33e-12 Glomerular filtration rate (creatinine); LIHC cis rs2455799 0.613 rs4684261 chr3:15796505 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs9534288 0.742 rs1022952 chr13:46649348 C/T cg15192986 chr13:46630673 CPB2 0.41 5.86 0.3 1.08e-8 Blood protein levels; LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.610 rs11752795 chr6:86287129 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.44 8.3 0.41 2.5e-15 Response to antipsychotic treatment; LIHC cis rs2274273 0.870 rs1109170 chr14:55785788 A/C cg01864836 chr14:55583639 NA -0.4 -7.45 -0.37 7.51e-13 Protein biomarker; LIHC cis rs10508774 0.810 rs11008987 chr10:32881651 C/T cg01819863 chr10:32635814 EPC1 0.61 5.9 0.3 8.79e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg06634786 chr22:41940651 POLR3H 0.81 8.62 0.42 2.59e-16 Vitiligo; LIHC cis rs9399135 0.967 rs4896125 chr6:135342569 C/T cg22676075 chr6:135203613 NA 0.39 6.32 0.32 8.12e-10 Red blood cell count; LIHC cis rs9399135 0.967 rs2297338 chr6:135375762 G/A cg22676075 chr6:135203613 NA 0.42 6.67 0.34 1.04e-10 Red blood cell count; LIHC cis rs12200782 1.000 rs6456742 chr6:26617075 T/C cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs7772486 0.641 rs9390374 chr6:146368175 A/T cg23711669 chr6:146136114 FBXO30 0.56 8.33 0.41 1.98e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs6058796 1.000 rs6141772 chr20:31246662 A/C cg02600331 chr11:130417168 NA 0.33 7.48 0.37 6.17e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs6430585 0.528 rs309162 chr2:136690783 T/A cg07305463 chr2:136567211 LCT -0.38 -5.93 -0.31 7.24e-9 Corneal structure; LIHC cis rs7208859 0.673 rs78799101 chr17:29215160 A/T cg14067834 chr17:29058358 SUZ12P 0.67 6.55 0.33 2.13e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg12419862 chr22:24373484 LOC391322 -0.66 -9.39 -0.45 8.42e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1538970 1.000 rs4660853 chr1:45849090 C/T cg24296786 chr1:45957014 TESK2 -0.5 -7.47 -0.37 6.61e-13 Platelet count; LIHC cis rs7552404 0.824 rs1251077 chr1:76189745 C/G cg10523679 chr1:76189770 ACADM -0.69 -14.36 -0.61 6.34e-37 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.41 -0.41 1.1e-15 Lymphocyte counts; LIHC cis rs1941023 0.503 rs12798266 chr11:60118851 G/A cg08716584 chr11:60157161 MS4A7 -0.34 -7.84 -0.39 5.6e-14 Congenital heart disease (maternal effect); LIHC cis rs4268898 0.552 rs7560342 chr2:24371691 T/C cg06627628 chr2:24431161 ITSN2 0.47 6.9 0.35 2.46e-11 Asthma; LIHC cis rs4930103 0.935 rs2839698 chr11:2018853 G/A cg06197492 chr11:2016605 H19 0.38 6.07 0.31 3.34e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs614226 0.938 rs12857 chr12:120933946 T/G cg01236616 chr12:121019343 POP5 1.24 19.35 0.72 7.05e-57 Type 1 diabetes nephropathy; LIHC cis rs3096299 0.933 rs28608022 chr16:89454292 C/T cg08392591 chr16:89556376 ANKRD11 0.41 6.12 0.31 2.62e-9 Multiple myeloma (IgH translocation); LIHC cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg18404041 chr3:52824283 ITIH1 -0.56 -9.13 -0.44 6.13e-18 Bipolar disorder; LIHC cis rs7107174 0.892 rs1017907 chr11:77959124 A/T cg02023728 chr11:77925099 USP35 0.46 8.72 0.43 1.22e-16 Testicular germ cell tumor; LIHC cis rs1707322 0.721 rs6697821 chr1:46216722 A/G cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05694744 chr17:8191820 RANGRF;SLC25A35 0.4 6.33 0.32 7.83e-10 Pancreatic cancer; LIHC cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.07 0.31 3.47e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1816752 0.819 rs4770664 chr13:24988833 C/T cg22771759 chr13:24902376 NA 0.3 6.04 0.31 4e-9 Obesity-related traits; LIHC cis rs8016982 0.632 rs8010219 chr14:81696982 A/G cg01989461 chr14:81687754 GTF2A1 0.53 9.2 0.45 3.66e-18 Schizophrenia; LIHC cis rs8062405 0.755 rs17707300 chr16:28593347 A/G cg00204512 chr16:28754710 NA 0.41 7.05 0.36 1.01e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2404602 0.583 rs12898415 chr15:76574232 C/T cg03037974 chr15:76606532 NA 0.89 23.12 0.78 6.85e-72 Blood metabolite levels; LIHC cis rs9503598 0.502 rs2326231 chr6:3433925 T/G cg00476032 chr6:3446245 SLC22A23 -0.32 -5.8 -0.3 1.52e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg06453172 chr10:134556979 INPP5A 0.66 8.32 0.41 2.05e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs7193541 0.662 rs8058133 chr16:74657485 A/T cg23598604 chr1:99732472 LPPR4 -0.31 -6.3 -0.32 9.17e-10 Multiple myeloma; LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.59 -8.41 -0.41 1.13e-15 Lymphocyte counts; LIHC cis rs1023500 0.573 rs4822088 chr22:42470589 G/C cg05082376 chr22:42548792 NA -0.39 -5.77 -0.3 1.75e-8 Schizophrenia; LIHC cis rs7224737 1.000 rs7214921 chr17:40294025 T/C cg20291162 chr17:40259547 DHX58 -0.4 -6.38 -0.33 5.82e-10 Fibrinogen levels; LIHC cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg11764359 chr7:65958608 NA 0.57 5.95 0.31 6.62e-9 Diabetic kidney disease; LIHC cis rs1403694 0.695 rs11919484 chr3:186432839 G/T cg12454167 chr3:186435060 KNG1 0.39 9.09 0.44 7.92e-18 Blood protein levels; LIHC cis rs2576037 0.526 rs998819 chr18:44564181 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.69 -11.05 -0.51 1.84e-24 Personality dimensions; LIHC cis rs9916302 0.904 rs6503507 chr17:37525274 C/T cg00129232 chr17:37814104 STARD3 0.4 6.41 0.33 4.95e-10 Glomerular filtration rate (creatinine); LIHC cis rs60871478 0.704 rs62432895 chr7:822050 C/G cg27478167 chr7:817139 HEATR2 -0.4 -5.76 -0.3 1.84e-8 Cerebrospinal P-tau181p levels; LIHC cis rs6754311 0.551 rs10928545 chr2:136501840 A/G cg07305463 chr2:136567211 LCT 0.35 6.2 0.32 1.59e-9 Mosquito bite size; LIHC trans rs6489882 0.703 rs10850097 chr12:113361117 C/T cg10175203 chr3:128143634 NA 0.39 6.39 0.33 5.32e-10 Chronic lymphocytic leukemia; LIHC trans rs17685 0.753 rs4573217 chr7:75733946 G/A cg19862616 chr7:65841803 NCRNA00174 0.92 18.56 0.71 1.05e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12500138 0.850 rs115146063 chr4:166193694 C/T cg25064052 chr4:166216151 KLHL2 -0.64 -5.89 -0.3 9.49e-9 Cognitive function; LIHC cis rs919433 0.783 rs788011 chr2:198230771 A/G cg10820045 chr2:198174542 NA 0.56 9.01 0.44 1.46e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.09 12.2 0.55 1.19e-28 Platelet count; LIHC cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg21448741 chr8:58168803 NA 0.35 6.55 0.33 2.12e-10 Developmental language disorder (linguistic errors); LIHC cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg24101359 chr6:42928495 GNMT 0.46 6.3 0.32 8.92e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg00343986 chr7:65444356 GUSB 0.44 6.24 0.32 1.29e-9 Aortic root size; LIHC cis rs2637266 0.967 rs7900230 chr10:78366879 A/G cg18941641 chr10:78392320 NA 0.27 5.72 0.3 2.35e-8 Pulmonary function; LIHC cis rs6539247 0.509 rs4275717 chr12:106445852 G/A cg20883310 chr12:106464547 NUAK1 0.45 7.28 0.37 2.29e-12 Attention function in attention deficit hyperactive disorder; LIHC trans rs11098499 0.644 rs17517414 chr4:120262101 G/C cg25214090 chr10:38739885 LOC399744 0.45 7.4 0.37 1.08e-12 Corneal astigmatism; LIHC cis rs2072499 0.966 rs2842865 chr1:156159532 G/A cg25208724 chr1:156163844 SLC25A44 0.94 15.95 0.65 3.43e-43 Testicular germ cell tumor; LIHC cis rs875971 0.862 rs778697 chr7:65870426 G/A cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs367615 0.506 rs2914684 chr5:108775110 C/T cg17395555 chr5:108820864 NA -0.31 -6.7 -0.34 8.8e-11 Colorectal cancer (SNP x SNP interaction); LIHC cis rs929354 0.772 rs3802118 chr7:156986814 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.11 0.55 2.47e-28 Body mass index; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg10990685 chr12:120720139 NME2P1 0.44 6.37 0.33 6.17e-10 Myopia (pathological); LIHC cis rs796364 1.000 rs11895190 chr2:200838613 A/G cg23649088 chr2:200775458 C2orf69 -0.5 -6.15 -0.32 2.14e-9 Schizophrenia; LIHC cis rs1046896 0.594 rs4075209 chr17:80800027 G/T cg02398342 chr17:80708632 TBCD;FN3K 0.41 6.27 0.32 1.1e-9 Glycated hemoglobin levels; LIHC cis rs1670533 1.000 rs2014318 chr4:1068778 C/T cg27284194 chr4:1044797 NA -0.58 -8.67 -0.42 1.81e-16 Recombination rate (females); LIHC cis rs7945718 0.621 rs10765984 chr11:12672669 T/C cg25843174 chr11:12811716 TEAD1 0.33 7.66 0.38 1.88e-13 Educational attainment (years of education); LIHC cis rs9486719 1.000 rs13208422 chr6:96892119 C/T cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs875971 0.767 rs1695815 chr7:65831344 A/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs12579753 1.000 rs10862372 chr12:82249804 C/T cg07988820 chr12:82153109 PPFIA2 -0.47 -5.76 -0.3 1.9e-8 Resting heart rate; LIHC cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.33e-30 Menopause (age at onset); LIHC cis rs9814567 0.806 rs4074522 chr3:134325626 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.6 9.53 0.46 3.07e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs34375054 0.624 rs73233307 chr12:125675873 G/C cg25124228 chr12:125621409 AACS -0.42 -6.85 -0.35 3.34e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs826838 0.900 rs1403523 chr12:39130570 T/A cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs2834188 0.924 rs2007849 chr21:34681116 G/A cg14352951 chr21:34696688 IFNAR1 0.46 6.39 0.33 5.51e-10 Narcolepsy; LIHC cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg10774155 chr7:65338427 VKORC1L1 0.45 6.71 0.34 7.86e-11 Calcium levels; LIHC cis rs868036 0.718 rs2241420 chr15:68082816 G/A cg24579218 chr15:68104479 NA -0.34 -5.94 -0.31 7.12e-9 Restless legs syndrome; LIHC cis rs2075371 0.932 rs2544215 chr7:133987896 T/C cg11752832 chr7:134001865 SLC35B4 0.51 7.74 0.39 1.13e-13 Mean platelet volume; LIHC trans rs1814175 0.817 rs10128730 chr11:50023369 G/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.17 0.61 3.36e-36 Prudent dietary pattern; LIHC cis rs11719291 0.504 rs71324924 chr3:48865444 G/A cg00383909 chr3:49044727 WDR6 0.96 7.95 0.4 2.65e-14 Cognitive function; LIHC cis rs797680 0.856 rs7537403 chr1:93777724 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.67e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs7605378 0.528 rs281791 chr2:200850402 A/G cg17644776 chr2:200775616 C2orf69 -0.45 -6.64 -0.34 1.21e-10 Osteoporosis; LIHC cis rs4665809 0.549 rs17527979 chr2:26428132 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.48 -6.26 -0.32 1.16e-9 Gut microbiome composition (summer); LIHC cis rs644799 1.000 rs12786522 chr11:95522858 G/C cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.78 0.3 1.71e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9303401 0.659 rs9303399 chr17:56672309 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.18 0.55 1.35e-28 Cognitive test performance; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg24846343 chr22:24311635 DDTL 0.66 12.92 0.57 2.28e-31 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs769267 0.896 rs7253807 chr19:19631444 A/T cg15052019 chr19:19431593 KIAA0892;SF4 0.46 6.22 0.32 1.44e-9 Tonsillectomy; LIHC trans rs7395662 0.517 rs2021248 chr11:49013054 C/T cg15704280 chr7:45808275 SEPT13 -0.51 -7.53 -0.38 4.49e-13 HDL cholesterol; LIHC cis rs7131987 0.903 rs7302129 chr12:29415280 A/T cg21522988 chr12:29376872 FAR2 0.28 6.22 0.32 1.45e-9 QT interval; LIHC cis rs7959452 0.535 rs7308481 chr12:69659299 A/G cg20891283 chr12:69753455 YEATS4 0.8 14.85 0.63 7.89e-39 Blood protein levels; LIHC cis rs10883723 0.810 rs10883728 chr10:104269301 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.84 -12.91 -0.57 2.4e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4965272 0.761 rs11631536 chr15:100560058 C/A cg09918751 chr15:100517450 ADAMTS17 -0.45 -6.29 -0.32 9.92e-10 Gastroesophageal reflux disease; LIHC cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg10802521 chr3:52805072 NEK4 -0.44 -7.27 -0.37 2.53e-12 Bipolar disorder; LIHC cis rs1046896 0.739 rs2379358 chr17:80741612 G/A cg19500275 chr17:80737654 TBCD 0.52 7.64 0.38 2.21e-13 Glycated hemoglobin levels; LIHC cis rs11761441 0.602 rs7801619 chr7:94006 C/T cg25149888 chr7:81075 NA 0.26 5.71 0.3 2.45e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs4853036 0.951 rs6738783 chr2:70120608 A/G cg02498382 chr2:70120550 SNRNP27 -0.38 -5.97 -0.31 6.1e-9 Colorectal or endometrial cancer; LIHC cis rs1551570 0.819 rs11666402 chr19:10219076 A/G cg16327482 chr19:10226339 EIF3G 0.45 7.99 0.4 2.05e-14 Narcolepsy; LIHC cis rs9486715 0.867 rs3849199 chr6:97049191 T/C cg18709589 chr6:96969512 KIAA0776 -0.35 -6.3 -0.32 9.13e-10 Headache; LIHC cis rs12497850 0.931 rs4974085 chr3:48924900 C/T cg06212747 chr3:49208901 KLHDC8B 0.58 7.69 0.38 1.58e-13 Parkinson's disease; LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.1 -0.31 2.87e-9 Total body bone mineral density; LIHC cis rs12477438 0.520 rs4347885 chr2:99804007 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.01 0.48 7.5e-21 Chronic sinus infection; LIHC cis rs12477438 0.798 rs4324365 chr2:99623845 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.55 -0.53 2.75e-26 Chronic sinus infection; LIHC trans rs61041384 0.661 rs4474478 chr12:123734368 C/T cg07919128 chr17:18022025 MYO15A 0.68 6.7 0.34 8.34e-11 Schizophrenia; LIHC trans rs1814175 0.511 rs61905634 chr11:49819736 G/A cg15704280 chr7:45808275 SEPT13 -1.03 -24.17 -0.79 5.7e-76 Height; LIHC cis rs4771122 0.740 rs1006353 chr13:28047269 A/G cg22138327 chr13:27999177 GTF3A -0.47 -7.35 -0.37 1.46e-12 Body mass index; LIHC cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg11062466 chr8:58055876 NA 0.4 5.78 0.3 1.66e-8 Developmental language disorder (linguistic errors); LIHC cis rs7618501 0.699 rs2777888 chr3:49898000 A/G cg21467203 chr3:49911342 NA -0.52 -9.03 -0.44 1.29e-17 Intelligence (multi-trait analysis); LIHC cis rs2380220 0.751 rs117986000 chr6:95923454 A/C cg04719120 chr6:96025338 MANEA -0.62 -6.47 -0.33 3.35e-10 Behavioural disinhibition (generation interaction); LIHC cis rs35110281 0.712 rs8133523 chr21:45062403 A/G cg21573476 chr21:45109991 RRP1B -0.57 -10.89 -0.51 6.8e-24 Mean corpuscular volume; LIHC cis rs769267 0.930 rs7254927 chr19:19404786 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.6 9.48 0.46 4.3e-19 Tonsillectomy; LIHC cis rs79149102 0.579 rs12591175 chr15:75356073 C/T cg09165964 chr15:75287851 SCAMP5 -0.6 -7.78 -0.39 8.66e-14 Lung cancer; LIHC cis rs6461049 0.608 rs3800923 chr7:2184673 A/G cg14004847 chr7:1930337 MAD1L1 -0.4 -6.01 -0.31 4.88e-9 Schizophrenia; LIHC cis rs908922 0.651 rs4845444 chr1:152530125 G/A cg20991723 chr1:152506922 NA 0.58 10.04 0.48 5.86e-21 Hair morphology; LIHC cis rs2243480 1.000 rs778679 chr7:65840911 A/G cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs559928 0.606 rs60394481 chr11:63909035 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 7.43 0.37 8.8e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs11112613 0.713 rs11112588 chr12:105943801 A/C cg03607813 chr12:105948248 NA 0.66 12.75 0.57 9.71e-31 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs4919694 1.000 rs4917986 chr10:104630181 T/C cg04362960 chr10:104952993 NT5C2 0.71 7.23 0.36 3.15e-12 Arsenic metabolism; LIHC cis rs2115630 0.691 rs61322921 chr15:85163638 T/C cg12501888 chr15:85177176 SCAND2 -0.48 -7.3 -0.37 2e-12 P wave terminal force; LIHC cis rs2576037 0.583 rs541634 chr18:44420271 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.94 0.51 4.21e-24 Personality dimensions; LIHC cis rs17685 0.671 rs10274404 chr7:75706634 G/A cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.64e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs732505 1.000 rs8109716 chr19:5585245 G/A cg26242866 chr19:5711310 LONP1 0.88 6.48 0.33 3.28e-10 vWF and FVIII levels; LIHC cis rs921968 0.509 rs556468 chr2:219355794 G/A cg02176678 chr2:219576539 TTLL4 0.52 7.09 0.36 7.61e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs1843834 0.858 rs12105685 chr2:225513164 A/G cg22509189 chr2:225307070 NA -0.61 -7.37 -0.37 1.31e-12 IgE levels in asthmatics (D.p. specific); LIHC trans rs1814175 0.588 rs1794144 chr11:49918233 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs4727027 0.704 rs2269972 chr7:148914047 C/T cg23583168 chr7:148888333 NA 0.69 11.09 0.51 1.23e-24 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs600806 0.850 rs4970729 chr1:109979202 G/A cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.52 -0.38 4.87e-13 Intelligence (multi-trait analysis); LIHC cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg11502198 chr6:26597334 ABT1 0.63 9.89 0.47 1.85e-20 Intelligence (multi-trait analysis); LIHC cis rs34172651 0.917 rs7204281 chr16:24784475 C/T cg00339695 chr16:24857497 SLC5A11 0.52 7.92 0.39 3.35e-14 Intelligence (multi-trait analysis); LIHC cis rs1403694 0.695 rs10937266 chr3:186433075 G/A cg12454167 chr3:186435060 KNG1 0.39 9.09 0.44 7.92e-18 Blood protein levels; LIHC cis rs12477438 0.520 rs13035311 chr2:99717322 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.2 21.41 0.76 4.22e-65 Chronic sinus infection; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12038521 chr19:2111714 AP3D1 0.42 6.1 0.31 2.86e-9 Longevity; LIHC cis rs2439831 0.618 rs8023508 chr15:44176103 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.6 -8.59 -0.42 3.07e-16 Lung cancer in ever smokers; LIHC trans rs66573146 1.000 rs55833486 chr4:6978729 C/A cg07817883 chr1:32538562 TMEM39B 1.1 9.18 0.44 4.1e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs8180040 0.966 rs11710322 chr3:47331136 C/T cg16586182 chr3:47516702 SCAP 0.58 10.71 0.5 2.91e-23 Colorectal cancer; LIHC cis rs6752107 0.935 rs10929325 chr2:234151031 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.48 7.14 0.36 5.8e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9814567 1.000 rs7645295 chr3:134307734 T/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.43 -6.18 -0.32 1.79e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs881375 1.000 rs10760121 chr9:123647915 G/T cg14580859 chr9:123691850 NA 0.4 6.85 0.35 3.55e-11 Rheumatoid arthritis; LIHC cis rs7927771 0.524 rs10838758 chr11:47771476 T/C cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs12980942 1.000 rs4456618 chr19:41813957 G/C cg25627403 chr19:41769009 HNRNPUL1 0.49 6.12 0.31 2.58e-9 Coronary artery disease; LIHC cis rs4788570 0.584 rs6499530 chr16:71723089 C/G cg06353428 chr16:71660113 MARVELD3 1.31 14.48 0.62 2.23e-37 Intelligence (multi-trait analysis); LIHC cis rs801193 0.613 rs2016325 chr7:66323500 T/C cg11764359 chr7:65958608 NA -0.61 -7.69 -0.38 1.6e-13 Aortic root size; LIHC cis rs2645694 0.533 rs2703125 chr4:77819900 T/C cg03477792 chr4:77819574 ANKRD56 0.59 8.68 0.42 1.64e-16 Emphysema distribution in smoking; LIHC trans rs877282 0.898 rs11253339 chr10:759640 C/T cg22713356 chr15:30763199 NA 1.36 11.89 0.54 1.56e-27 Uric acid levels; LIHC cis rs7208859 0.673 rs1347360 chr17:28914532 T/C cg13385521 chr17:29058706 SUZ12P 0.67 6.57 0.33 1.86e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs5770917 1.000 rs3180872 chr22:51017394 G/C cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.43 -6.23 -0.32 1.38e-9 Narcolepsy; LIHC cis rs921968 0.541 rs647990 chr2:219441428 T/C cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.37e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs9322817 0.691 rs2486143 chr6:105308593 A/G cg02098413 chr6:105308735 HACE1 0.44 8.3 0.41 2.4e-15 Thyroid stimulating hormone; LIHC cis rs7904368 0.754 rs17139234 chr10:16849732 G/T cg14835575 chr10:16859367 RSU1 0.65 8.81 0.43 6.6e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg25894440 chr7:65020034 NA -0.53 -6.15 -0.32 2.2e-9 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.05e-11 Diabetic kidney disease; LIHC cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg05025164 chr4:1340916 KIAA1530 0.76 11.84 0.54 2.38e-27 Longevity; LIHC cis rs9522267 0.535 rs7339347 chr13:112237920 C/T cg10483660 chr13:112241077 NA -0.22 -5.95 -0.31 6.51e-9 Hepatitis; LIHC cis rs6466055 0.669 rs10808141 chr7:104715490 T/G cg04380332 chr7:105027541 SRPK2 -0.33 -6.21 -0.32 1.5e-9 Schizophrenia; LIHC cis rs992157 0.804 rs7559525 chr2:219150307 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.78 -12.48 -0.56 9.93e-30 Colorectal cancer; LIHC cis rs4700695 0.623 rs152943 chr5:65238285 A/G cg21114390 chr5:65439923 SFRS12 0.44 6.15 0.32 2.2e-9 Facial morphology (factor 19); LIHC cis rs4555082 0.794 rs2735827 chr14:105710600 T/A cg10792982 chr14:105748885 BRF1 0.44 5.93 0.31 7.44e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs12744310 0.887 rs72667608 chr1:41794773 A/G cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.95e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs12824058 0.831 rs4759658 chr12:130815872 C/T cg24838063 chr12:130822603 PIWIL1 0.66 9.79 0.47 4.16e-20 Menopause (age at onset); LIHC cis rs796364 0.951 rs281776 chr2:200834282 T/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.18 0.4 5.7e-15 Schizophrenia; LIHC cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -10.1 -0.48 3.53e-21 Platelet count; LIHC cis rs8062405 1.000 rs9972693 chr16:28859802 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.33e-30 Menopause (age at onset); LIHC cis rs3892630 0.588 rs2287881 chr19:33333155 A/G cg22980127 chr19:33182716 NUDT19 -0.99 -13.13 -0.58 3.72e-32 Red blood cell traits; LIHC cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg07092213 chr7:1199455 ZFAND2A -0.44 -6.32 -0.32 8.29e-10 Longevity;Endometriosis; LIHC trans rs1994135 0.647 rs1351681 chr12:33698724 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.55 0.33 2.16e-10 Resting heart rate; LIHC cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.95 8.45 0.42 8.22e-16 Platelet count; LIHC cis rs7412746 0.611 rs10888394 chr1:150749913 C/T cg17724175 chr1:150552817 MCL1 0.46 9.16 0.44 4.94e-18 Melanoma; LIHC cis rs3749237 0.595 rs1050088 chr3:49570882 C/T cg02487422 chr3:49467188 NICN1 -0.37 -5.73 -0.3 2.19e-8 Resting heart rate; LIHC cis rs1055129 0.537 rs2467100 chr17:73949038 C/G cg14829360 chr17:73884958 NA -0.37 -6.32 -0.32 7.99e-10 White matter hyperintensity burden; LIHC cis rs9611565 0.546 rs5758431 chr22:42109917 A/G cg03806693 chr22:41940476 POLR3H 0.83 9.36 0.45 1.07e-18 Vitiligo; LIHC cis rs921968 0.643 rs600057 chr2:219456737 A/G cg02985541 chr2:219472218 PLCD4 0.44 8.5 0.42 5.86e-16 Mean corpuscular hemoglobin concentration; LIHC trans rs12478296 0.681 rs73007114 chr2:242984903 T/C cg01596870 chr19:55963115 NA -0.58 -6.73 -0.34 7.19e-11 Obesity-related traits; LIHC cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg11279151 chr3:101281821 RG9MTD1 0.39 5.95 0.31 6.57e-9 Colorectal cancer; LIHC cis rs7568458 0.660 rs2289972 chr2:85766545 C/T cg02493740 chr2:85810744 VAMP5 -0.47 -7.84 -0.39 5.6e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs875971 1.000 rs12532998 chr7:65967459 A/C cg11764359 chr7:65958608 NA 0.91 16.89 0.67 5.59e-47 Aortic root size; LIHC cis rs7772486 0.875 rs10457793 chr6:146415403 A/G cg23711669 chr6:146136114 FBXO30 0.65 10.91 0.51 5.7e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg11764359 chr7:65958608 NA 0.57 6.0 0.31 4.9e-9 Diabetic kidney disease; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg19409381 chr4:83351505 HNRPDL;ENOPH1 -0.58 -6.25 -0.32 1.21e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs4631830 0.863 rs57263518 chr10:51519154 A/G cg20129853 chr10:51489980 NA -0.43 -9.35 -0.45 1.22e-18 Prostate-specific antigen levels; LIHC cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg18305652 chr10:134549665 INPP5A 0.44 6.37 0.33 5.95e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs867371 0.929 rs1501371 chr15:82460440 A/C cg18393722 chr15:85113863 UBE2QP1 -0.43 -7.34 -0.37 1.62e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7552404 0.924 rs7544117 chr1:76158246 A/G cg10523679 chr1:76189770 ACADM 0.67 9.95 0.47 1.22e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs13161895 1.000 rs3797763 chr5:179439516 C/T cg06664874 chr5:179499304 RNF130 -0.58 -7.12 -0.36 6.37e-12 LDL cholesterol; LIHC cis rs4953911 0.793 rs13014122 chr2:135050622 G/A cg18482303 chr2:135041380 MGAT5 0.37 5.8 0.3 1.5e-8 Multiple sclerosis (severity); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11954230 chr10:105677556 OBFC1 0.5 6.81 0.35 4.46e-11 Pancreatic cancer; LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg18279126 chr7:2041391 MAD1L1 0.39 6.51 0.33 2.74e-10 Bipolar disorder and schizophrenia; LIHC cis rs1865721 0.656 rs727894 chr18:73137117 C/T cg26385618 chr18:73139727 C18orf62 -0.29 -8.32 -0.41 2.08e-15 Intelligence; LIHC cis rs9457247 0.967 rs443570 chr6:167389925 G/A cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs1395 0.961 rs4665965 chr2:27536380 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 0.42 5.81 0.3 1.45e-8 Blood metabolite levels; LIHC cis rs5769707 0.554 rs10854876 chr22:50010570 T/C cg01652190 chr22:50026171 C22orf34 -0.34 -7.51 -0.38 5.34e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6754311 0.731 rs1470457 chr2:136581848 A/G cg07305463 chr2:136567211 LCT -0.35 -6.62 -0.34 1.42e-10 Mosquito bite size; LIHC cis rs10411936 0.962 rs10404046 chr19:16477255 G/C cg10248733 chr19:16607483 C19orf44;CALR3 0.43 5.76 0.3 1.86e-8 White blood cell count;Multiple sclerosis; LIHC cis rs4423214 1.000 rs3794060 chr11:71187679 C/T cg24826892 chr11:71159390 DHCR7 0.5 6.38 0.33 5.79e-10 Vitamin D levels; LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs853679 0.517 rs1947862 chr6:28105196 C/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09993119 chr22:41601085 L3MBTL2 0.47 6.38 0.33 5.77e-10 Pancreatic cancer; LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.45 7.4 0.37 1.08e-12 Height; LIHC cis rs5769765 0.908 rs4074304 chr22:50309446 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.85 -10.37 -0.49 4.36e-22 Schizophrenia; LIHC cis rs17685 0.672 rs56343450 chr7:75796235 C/T cg04592579 chr7:75616294 TMEM120A 0.41 7.0 0.35 1.33e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs826838 1.000 rs10880826 chr12:38672787 G/C cg26384229 chr12:38710491 ALG10B 1.08 14.69 0.62 3.15e-38 Heart rate; LIHC cis rs3789045 0.560 rs4553256 chr1:204411144 C/T cg17419461 chr1:204415978 PIK3C2B -0.54 -8.41 -0.41 1.12e-15 Educational attainment (college completion); LIHC cis rs11760633 0.615 rs11767667 chr7:1840557 C/T cg23422044 chr7:1970798 MAD1L1 -0.39 -6.02 -0.31 4.61e-9 Coronary artery disease; LIHC cis rs8180040 0.800 rs6768221 chr3:47296899 C/G cg16586182 chr3:47516702 SCAP 0.51 9.01 0.44 1.45e-17 Colorectal cancer; LIHC cis rs892961 0.932 rs3987887 chr17:75414862 T/C cg05865280 chr17:75406074 SEPT9 0.64 13.05 0.58 7.58e-32 Airflow obstruction; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13357821 chr7:101707668 CUX1 -0.36 -6.38 -0.33 5.83e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs919433 1.000 rs6741380 chr2:198165121 A/G cg03934865 chr2:198174659 NA 0.6 9.87 0.47 2.26e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11971779 0.648 rs6974099 chr7:139098566 A/T cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs7208859 0.673 rs73265624 chr17:29232066 G/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg02931644 chr1:25747376 RHCE -0.34 -7.49 -0.38 5.84e-13 Erythrocyte sedimentation rate; LIHC cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs7668874 0.779 rs1821009 chr4:116807350 C/T cg08917878 chr5:172668965 NA -0.31 -6.14 -0.32 2.26e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs9814567 1.000 rs7429866 chr3:134236306 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg25072359 chr17:41440525 NA 0.39 6.22 0.32 1.47e-9 Menopause (age at onset); LIHC cis rs208520 0.690 rs207740 chr6:66764132 T/G cg07460842 chr6:66804631 NA 0.81 9.21 0.45 3.34e-18 Exhaled nitric oxide output; LIHC cis rs780096 0.526 rs704795 chr2:27716494 G/A cg21747090 chr2:27597821 SNX17 -0.42 -6.33 -0.32 7.8e-10 Total body bone mineral density; LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg21448741 chr8:58168803 NA 0.34 6.31 0.32 8.5e-10 Developmental language disorder (linguistic errors); LIHC cis rs7103648 0.712 rs10838703 chr11:47422861 C/G cg20307385 chr11:47447363 PSMC3 0.88 12.42 0.56 1.7e-29 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs4699052 0.963 rs6533066 chr4:104163607 C/G cg16532752 chr4:104119610 CENPE -0.4 -6.3 -0.32 9.05e-10 Testicular germ cell tumor; LIHC cis rs17102423 0.755 rs7161394 chr14:65563309 G/T cg11161011 chr14:65562177 MAX -0.52 -7.52 -0.38 4.87e-13 Obesity-related traits; LIHC cis rs10870270 0.956 rs7915388 chr10:133734972 G/A cg26149184 chr10:133730230 NA 0.46 7.34 0.37 1.56e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs7178375 1.000 rs1474382 chr15:31214649 A/G cg04373760 chr16:53404718 NA 0.59 7.44 0.37 8.47e-13 Hypertriglyceridemia; LIHC cis rs5769765 0.955 rs9616394 chr22:50314927 G/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.87 -10.78 -0.5 1.56e-23 Schizophrenia; LIHC cis rs3099143 0.901 rs76101229 chr15:77134975 C/T cg21673338 chr15:77095150 SCAPER -0.5 -6.71 -0.34 8.27e-11 Recalcitrant atopic dermatitis; LIHC trans rs6952808 0.689 rs1107591 chr7:2041638 G/A cg04565464 chr8:145669602 NFKBIL2 0.39 6.55 0.33 2.09e-10 Bipolar disorder and schizophrenia; LIHC cis rs3960554 1.000 rs3960554 chr7:75845597 G/T cg01364799 chr7:75623366 TMEM120A -0.47 -6.53 -0.33 2.33e-10 Eotaxin levels; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs8141529 0.748 rs1318025 chr22:29283757 C/T cg15103426 chr22:29168792 CCDC117 0.57 9.3 0.45 1.74e-18 Lymphocyte counts; LIHC cis rs11758351 0.866 rs2069018 chr6:26205718 T/C cg01420254 chr6:26195488 NA 0.51 5.77 0.3 1.77e-8 Gout;Renal underexcretion gout; LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg21747090 chr2:27597821 SNX17 -0.46 -6.93 -0.35 2.08e-11 Total body bone mineral density; LIHC cis rs965469 1.000 rs6051724 chr20:3279338 T/C cg25506879 chr20:3388711 C20orf194 -0.55 -6.74 -0.34 6.9e-11 IFN-related cytopenia; LIHC cis rs9916302 0.706 rs8075737 chr17:37727316 C/T cg07936489 chr17:37558343 FBXL20 0.86 13.01 0.58 1.06e-31 Glomerular filtration rate (creatinine); LIHC cis rs7546668 0.948 rs12736181 chr1:15869284 G/A cg11706911 chr1:15910989 AGMAT 0.43 6.61 0.34 1.52e-10 Glomerular filtration rate (creatinine); LIHC cis rs477692 1.000 rs4750759 chr10:131436603 G/A cg05714579 chr10:131428358 MGMT -0.41 -6.65 -0.34 1.16e-10 Response to temozolomide; LIHC cis rs10779751 0.770 rs2486922 chr1:11124885 T/C cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg22541791 chr17:33905888 PEX12 0.37 6.42 0.33 4.57e-10 Calcium levels; LIHC cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg14983838 chr19:29218262 NA 0.5 7.53 0.38 4.44e-13 Methadone dose in opioid dependence; LIHC cis rs870825 0.616 rs2141257 chr4:185609463 C/T cg04058563 chr4:185651563 MLF1IP -0.74 -7.44 -0.37 8.24e-13 Blood protein levels; LIHC cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg02931644 chr1:25747376 RHCE -0.33 -7.06 -0.36 9.29e-12 Erythrocyte sedimentation rate; LIHC cis rs1185460 0.934 rs1006195 chr11:118958869 A/C cg23280166 chr11:118938394 VPS11 -0.54 -7.04 -0.36 1.06e-11 Coronary artery disease; LIHC cis rs295140 0.743 rs952530 chr2:201081745 A/G cg23649088 chr2:200775458 C2orf69 -0.45 -6.07 -0.31 3.31e-9 QT interval; LIHC cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg06873352 chr17:61820015 STRADA -0.57 -9.06 -0.44 1.06e-17 Prudent dietary pattern; LIHC cis rs57590327 0.503 rs13073613 chr3:81888512 C/A cg07356753 chr3:81810745 GBE1 -0.51 -7.88 -0.39 4.47e-14 Extraversion; LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg04234412 chr22:24373322 LOC391322 -0.73 -10.98 -0.51 3.19e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs238295 0.881 rs6116869 chr20:5594432 G/T cg24001556 chr20:5591874 RP5-1022P6.2 0.56 7.62 0.38 2.45e-13 Occipital cortical area (total cortical area interaction); LIHC trans rs2243480 1.000 rs402418 chr7:65509469 G/A cg10756647 chr7:56101905 PSPH 1.08 13.46 0.59 2e-33 Diabetic kidney disease; LIHC cis rs782590 1.000 rs782590 chr2:55843413 C/T cg18811423 chr2:55921094 PNPT1 0.98 15.03 0.63 1.42e-39 Metabolic syndrome; LIHC cis rs2370759 1.000 rs79578760 chr10:32611264 C/A cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs7762018 1.000 rs73242927 chr6:170129573 T/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.53 6.2 0.32 1.61e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 8.87 0.43 4.26e-17 Platelet count; LIHC cis rs919433 0.713 rs1455653 chr2:198478320 G/A cg03934865 chr2:198174659 NA 0.52 7.73 0.39 1.21e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10847980 0.590 rs77970074 chr12:123292186 T/G cg22842854 chr12:123319900 HIP1R 0.91 9.9 0.47 1.79e-20 Adiponectin levels; LIHC cis rs11105298 0.891 rs11105312 chr12:89920733 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.28 -0.37 2.34e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg09455208 chr3:40491958 NA -0.4 -8.03 -0.4 1.54e-14 Renal cell carcinoma; LIHC cis rs11112613 0.775 rs12305225 chr12:105963266 G/C cg03607813 chr12:105948248 NA 0.58 11.03 0.51 2.13e-24 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs13098911 0.540 rs13066516 chr3:45975443 C/T cg21656520 chr2:210867290 RPE 0.86 6.09 0.31 3.09e-9 Celiac disease; LIHC cis rs8141529 1.000 rs132534 chr22:29299806 T/C cg15103426 chr22:29168792 CCDC117 -0.46 -7.17 -0.36 4.59e-12 Lymphocyte counts; LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg06558623 chr16:89946397 TCF25 0.99 15.31 0.64 1.13e-40 Skin colour saturation; LIHC cis rs4808199 0.895 rs2163805 chr19:19575945 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.43 6.18 0.32 1.86e-9 Nonalcoholic fatty liver disease; LIHC cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.23 0.55 8.88e-29 Alzheimer's disease; LIHC cis rs9814567 1.000 rs11927068 chr3:134266321 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2257205 0.667 rs7214805 chr17:56931895 C/G cg12560992 chr17:57184187 TRIM37 0.67 7.22 0.36 3.29e-12 Pancreatic cancer; LIHC cis rs9388451 0.626 rs2875881 chr6:126072853 C/G cg05901451 chr6:126070800 HEY2 -0.69 -14.61 -0.62 6.62e-38 Brugada syndrome; LIHC cis rs5769765 0.728 rs6520064 chr22:50294469 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.15 -0.44 5.12e-18 Schizophrenia; LIHC cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg11502198 chr6:26597334 ABT1 0.63 9.82 0.47 3.15e-20 Intelligence (multi-trait analysis); LIHC cis rs9309473 0.718 rs6546829 chr2:73613789 C/G cg20560298 chr2:73613845 ALMS1 -0.51 -8.14 -0.4 7.45e-15 Metabolite levels; LIHC cis rs8044995 0.563 rs1110572 chr16:68396119 A/G cg03983715 chr16:68378420 PRMT7 -0.51 -5.97 -0.31 5.89e-9 Schizophrenia; LIHC cis rs9611565 0.921 rs2281332 chr22:41746212 T/C cg03806693 chr22:41940476 POLR3H -0.46 -6.03 -0.31 4.17e-9 Vitiligo; LIHC cis rs9309711 0.961 rs11692184 chr2:3480710 C/T cg10845886 chr2:3471009 TTC15 -0.57 -10.71 -0.5 2.73e-23 Neurofibrillary tangles; LIHC cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg06481639 chr22:41940642 POLR3H 0.61 5.87 0.3 1.02e-8 Vitiligo; LIHC cis rs7208859 0.562 rs8078897 chr17:29106257 T/G cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11212260 0.655 rs76853908 chr11:107274530 T/C cg25435332 chr11:107328525 CWF19L2 0.81 8.76 0.43 8.88e-17 IgG glycosylation; LIHC cis rs7726839 0.540 rs72703087 chr5:598029 C/T cg09021430 chr5:549028 NA -0.42 -8.43 -0.41 9.84e-16 Obesity-related traits; LIHC trans rs7618501 1.000 rs60205400 chr3:49800272 C/T cg21659725 chr3:3221576 CRBN 0.99 19.71 0.73 2.65e-58 Intelligence (multi-trait analysis); LIHC trans rs3745567 0.688 rs2241394 chr19:6685230 C/G cg24053061 chr12:107168846 RIC8B 0.66 6.08 0.31 3.28e-9 Complement C3 and C4 levels; LIHC cis rs66573146 0.656 rs56094305 chr4:6956086 C/T cg00086871 chr4:6988644 TBC1D14 0.8 6.06 0.31 3.61e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs5753618 0.561 rs2413049 chr22:31686144 A/G cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.45e-10 Colorectal cancer; LIHC cis rs11098499 0.604 rs17051352 chr4:120581427 G/A cg09307838 chr4:120376055 NA 0.67 9.62 0.46 1.56e-19 Corneal astigmatism; LIHC cis rs4654899 0.571 rs6692677 chr1:21251717 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.83 0.3 1.27e-8 Superior frontal gyrus grey matter volume; LIHC cis rs9916302 0.904 rs679995 chr17:37441679 A/T cg07936489 chr17:37558343 FBXL20 0.81 12.92 0.57 2.17e-31 Glomerular filtration rate (creatinine); LIHC cis rs4076764 1.000 rs12740984 chr1:163422151 A/G cg24596788 chr1:163392923 NA 0.23 7.11 0.36 6.87e-12 Motion sickness; LIHC cis rs7577696 0.597 rs11691939 chr2:32339561 A/G cg02381751 chr2:32503542 YIPF4 0.46 6.49 0.33 3.08e-10 Inflammatory biomarkers; LIHC cis rs7904368 0.806 rs7899853 chr10:16857603 A/T cg14835575 chr10:16859367 RSU1 0.67 9.36 0.45 1.09e-18 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 5.86e-12 Diabetic kidney disease; LIHC cis rs6570726 0.935 rs110289 chr6:145865176 C/G cg23711669 chr6:146136114 FBXO30 0.56 9.93 0.47 1.43e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs17826219 0.714 rs11650821 chr17:28968150 T/C cg14067834 chr17:29058358 SUZ12P 0.65 6.28 0.32 1.05e-9 Body mass index; LIHC cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg20887711 chr4:1340912 KIAA1530 0.63 9.34 0.45 1.23e-18 Longevity; LIHC cis rs2153535 0.580 rs6597325 chr6:8461053 A/C cg07606381 chr6:8435919 SLC35B3 0.8 11.8 0.54 3.57e-27 Motion sickness; LIHC cis rs34172651 0.545 rs9302428 chr16:24717600 C/G cg00339695 chr16:24857497 SLC5A11 -0.37 -6.16 -0.32 2.01e-9 Intelligence (multi-trait analysis); LIHC cis rs7613875 0.620 rs34312088 chr3:50032133 C/T cg24110177 chr3:50126178 RBM5 -0.53 -8.62 -0.42 2.59e-16 Body mass index; LIHC cis rs2979489 0.699 rs17554116 chr8:30419334 C/T cg26383811 chr8:30366931 RBPMS -0.67 -10.18 -0.48 1.94e-21 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs9467773 1.000 rs6926629 chr6:26499903 T/C cg09904177 chr6:26538194 HMGN4 0.66 13.79 0.6 1.01e-34 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.52 -0.38 4.9e-13 Initial pursuit acceleration; LIHC cis rs9457247 0.602 rs4710175 chr6:167467800 A/G cg12798992 chr6:167411361 FGFR1OP 0.43 6.21 0.32 1.55e-9 Crohn's disease; LIHC cis rs743757 1.000 rs2236984 chr3:50495487 A/C cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.16 0.32 2.04e-9 Diastolic blood pressure; LIHC cis rs12368653 0.545 rs2277324 chr12:58013175 G/A cg12615879 chr12:58013172 SLC26A10 0.35 6.77 0.34 5.52e-11 Multiple sclerosis; LIHC cis rs9733 0.596 rs12403255 chr1:150660412 C/T cg18016565 chr1:150552671 MCL1 0.58 11.38 0.52 1.16e-25 Tonsillectomy; LIHC cis rs2075371 0.830 rs2077671 chr7:133951204 C/T cg20476274 chr7:133979776 SLC35B4 0.75 12.92 0.57 2.25e-31 Mean platelet volume; LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg26338869 chr17:61819248 STRADA 0.6 8.77 0.43 8.48e-17 Prudent dietary pattern; LIHC cis rs10193935 0.901 rs12615383 chr2:42610551 A/G cg27598129 chr2:42591480 NA 0.78 11.99 0.54 6.66e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs898097 0.691 rs7222745 chr17:80907253 C/T cg15664640 chr17:80829946 TBCD -0.44 -7.45 -0.37 7.92e-13 Breast cancer; LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg09417038 chr21:47716443 C21orf57 -0.47 -7.21 -0.36 3.51e-12 Testicular germ cell tumor; LIHC cis rs12220238 1.000 rs6480723 chr10:75966366 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.51 0.33 2.74e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7319311 0.965 rs9583488 chr13:111031352 G/A cg05272587 chr13:111038400 COL4A2 0.36 7.64 0.38 2.21e-13 Bipolar disorder and schizophrenia; LIHC cis rs9291683 0.588 rs2240724 chr4:10021290 G/C cg11266682 chr4:10021025 SLC2A9 0.34 7.31 0.37 1.89e-12 Bone mineral density; LIHC cis rs611744 0.905 rs421695 chr8:109117403 T/C cg18478394 chr8:109455254 TTC35 0.34 5.76 0.3 1.89e-8 Dupuytren's disease; LIHC cis rs3806843 1.000 rs991918 chr5:140194858 C/T cg26395211 chr5:140044315 WDR55 -0.42 -6.25 -0.32 1.25e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs507080 0.922 rs7114216 chr11:118566234 A/G cg04173919 chr11:118528438 PHLDB1 0.36 6.68 0.34 9.83e-11 Serum metabolite levels; LIHC cis rs1775715 0.677 rs2799034 chr10:32175896 A/G cg14930904 chr10:32216787 ARHGAP12 0.36 6.25 0.32 1.22e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9549328 0.837 rs4907572 chr13:113647321 G/A cg18289306 chr13:113640169 MCF2L 0.44 6.97 0.35 1.69e-11 Systolic blood pressure; LIHC cis rs7927771 0.864 rs755555 chr11:47431966 C/T cg20307385 chr11:47447363 PSMC3 -0.47 -6.01 -0.31 4.75e-9 Subjective well-being; LIHC cis rs854765 0.647 rs6502637 chr17:17986098 A/G cg04398451 chr17:18023971 MYO15A -0.66 -10.92 -0.51 5.13e-24 Total body bone mineral density; LIHC cis rs2153535 0.580 rs6597332 chr6:8504748 C/G cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.72e-14 Motion sickness; LIHC cis rs17401966 1.000 rs17410793 chr1:10391886 A/G cg19773385 chr1:10388646 KIF1B -0.46 -8.03 -0.4 1.55e-14 Hepatocellular carcinoma; LIHC cis rs1401999 1.000 rs6767013 chr3:183680102 G/A cg01324343 chr3:183735012 ABCC5 0.76 12.9 0.57 2.71e-31 Anterior chamber depth; LIHC cis rs6582630 0.512 rs11181007 chr12:38266700 C/T cg26384229 chr12:38710491 ALG10B -0.44 -5.8 -0.3 1.49e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs2841277 0.708 rs11851053 chr14:105407208 T/C cg15352829 chr14:105391018 PLD4 -0.43 -9.23 -0.45 2.83e-18 Rheumatoid arthritis; LIHC cis rs10792665 0.512 rs11233361 chr11:82597245 C/T cg24227371 chr11:82718527 RAB30 -0.28 -6.59 -0.34 1.68e-10 Obesity-related traits; LIHC cis rs801193 1.000 rs2659915 chr7:66153101 A/G cg18876405 chr7:65276391 NA 0.44 7.73 0.39 1.18e-13 Aortic root size; LIHC cis rs9486715 1.000 rs2273621 chr6:97058553 A/G cg06623918 chr6:96969491 KIAA0776 -0.86 -14.13 -0.61 4.82e-36 Headache; LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg01420254 chr6:26195488 NA 0.51 5.77 0.3 1.77e-8 Gout;Renal underexcretion gout; LIHC cis rs7523273 0.606 rs2796268 chr1:207925192 G/A cg22525895 chr1:207977042 MIR29B2 0.62 10.19 0.48 1.85e-21 Schizophrenia; LIHC cis rs9381040 0.610 rs2268191 chr6:41027653 G/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.39 -6.02 -0.31 4.41e-9 Alzheimer's disease (late onset); LIHC cis rs812925 0.519 rs1186696 chr2:61660483 A/C cg14146966 chr2:61757674 XPO1 0.39 6.31 0.32 8.52e-10 Immature fraction of reticulocytes; LIHC cis rs727563 0.635 rs5751141 chr22:42107745 A/G cg03806693 chr22:41940476 POLR3H 0.92 9.72 0.47 6.91e-20 Crohn's disease;Inflammatory bowel disease; LIHC cis rs35883536 1.000 rs1855798 chr1:101114191 T/C cg14515779 chr1:101123966 NA -0.65 -12.71 -0.57 1.36e-30 Monocyte count; LIHC cis rs244293 0.965 rs8068337 chr17:53177899 T/C cg19360675 chr17:53046073 COX11;STXBP4 0.51 7.58 0.38 3.26e-13 Menarche (age at onset); LIHC cis rs903552 1.000 rs4965873 chr15:102004023 A/G cg16179521 chr15:102009894 PCSK6 0.43 5.88 0.3 9.57e-9 Diabetic kidney disease; LIHC cis rs5769707 0.935 rs5770594 chr22:50018497 G/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.68 -0.42 1.61e-16 Monocyte count;Monocyte percentage of white cells; LIHC trans rs208520 0.690 rs851459 chr6:66813989 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.85 -9.22 -0.45 3.03e-18 Exhaled nitric oxide output; LIHC cis rs11030122 0.661 rs12290747 chr11:3939650 T/C cg18678763 chr11:4115507 RRM1 -0.57 -8.55 -0.42 4.32e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs11711311 1.000 rs9855613 chr3:113448455 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.41 7.87 0.39 4.76e-14 IgG glycosylation; LIHC cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg18230493 chr5:56204884 C5orf35 -0.47 -6.55 -0.33 2.08e-10 Initial pursuit acceleration; LIHC cis rs9527 0.571 rs7096249 chr10:104618524 G/A cg15744005 chr10:104629667 AS3MT -0.46 -10.53 -0.49 1.2e-22 Arsenic metabolism; LIHC cis rs9768139 0.935 rs116290351 chr7:158119712 T/A cg25566285 chr7:158114605 PTPRN2 -0.26 -7.67 -0.38 1.84e-13 Calcium levels; LIHC cis rs4919087 0.961 rs11189120 chr10:99069493 G/T cg25902810 chr10:99078978 FRAT1 0.7 10.9 0.51 6.1e-24 Monocyte count; LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.61 9.63 0.46 1.44e-19 Height; LIHC cis rs9549367 0.662 rs3818334 chr13:113825174 C/G cg18105134 chr13:113819100 PROZ -0.75 -12.42 -0.56 1.73e-29 Platelet distribution width; LIHC cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg04317338 chr11:64019027 PLCB3 0.84 10.29 0.49 8.11e-22 Mean platelet volume; LIHC cis rs4268898 0.760 rs11125535 chr2:24528114 T/C cg06627628 chr2:24431161 ITSN2 0.47 6.87 0.35 3.11e-11 Asthma; LIHC cis rs75908454 1.000 rs117534547 chr6:169891608 G/A cg19338460 chr6:170058176 WDR27 -0.75 -6.8 -0.35 4.69e-11 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.15e-9 Menopause (age at onset); LIHC cis rs5769707 0.632 rs135877 chr22:50014002 A/G cg07959070 chr22:50026188 C22orf34 -0.34 -8.39 -0.41 1.32e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs908922 0.676 rs11205018 chr1:152496249 T/G cg20991723 chr1:152506922 NA 0.6 10.58 0.5 8.32e-23 Hair morphology; LIHC cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.94 0.31 7.14e-9 Schizophrenia; LIHC cis rs2274273 0.870 rs13379169 chr14:55741287 C/T cg01864836 chr14:55583639 NA -0.42 -7.8 -0.39 7.5e-14 Protein biomarker; LIHC cis rs600806 0.850 rs4970752 chr1:109930852 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs2075371 1.000 rs2244700 chr7:133987374 A/G cg11752832 chr7:134001865 SLC35B4 0.52 7.75 0.39 1.04e-13 Mean platelet volume; LIHC cis rs34172651 0.837 rs1978451 chr16:24818286 C/G cg00339695 chr16:24857497 SLC5A11 0.51 7.76 0.39 9.76e-14 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg12311346 chr5:56204834 C5orf35 -0.58 -7.52 -0.38 4.84e-13 Initial pursuit acceleration; LIHC cis rs1801251 0.752 rs709938 chr2:233746457 C/T cg25237894 chr2:233734115 C2orf82 -0.57 -11.11 -0.51 1.12e-24 Coronary artery disease; LIHC cis rs2637266 0.935 rs2637265 chr10:78326104 A/G cg18941641 chr10:78392320 NA 0.29 5.96 0.31 6.34e-9 Pulmonary function; LIHC cis rs17685 0.753 rs2108274 chr7:75781636 C/A cg04610667 chr7:75704037 NA -0.34 -6.13 -0.31 2.47e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12701220 0.895 rs12534778 chr7:1065861 C/T cg00990874 chr7:1149470 C7orf50 0.64 8.98 0.44 1.91e-17 Bronchopulmonary dysplasia; LIHC cis rs7523273 1.000 rs12410786 chr1:207976205 T/A cg22525895 chr1:207977042 MIR29B2 -0.68 -10.97 -0.51 3.38e-24 Schizophrenia; LIHC cis rs4819052 0.851 rs13047104 chr21:46673562 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.4 0.52 1.01e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7193541 0.684 rs7191665 chr16:74688948 T/G cg01733217 chr16:74700730 RFWD3 0.92 22.75 0.78 2.09e-70 Multiple myeloma; LIHC cis rs62179067 0.618 rs11886627 chr2:179942451 G/A cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs3768617 1.000 rs1360704 chr1:183099380 C/T ch.1.3577855R chr1:183094577 LAMC1 -0.48 -7.67 -0.38 1.8e-13 Fuchs's corneal dystrophy; LIHC trans rs9929218 0.954 rs4420522 chr16:68822971 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.18 -0.4 5.53e-15 Colorectal cancer; LIHC trans rs12752401 0.867 rs34777937 chr1:103036317 C/A cg17681729 chr19:740608 PALM 0.44 6.23 0.32 1.39e-9 Resistance to antihypertensive treatment in hypertension; LIHC trans rs1624005 0.967 rs1624272 chr14:43389468 C/T cg11960719 chr5:1510684 LPCAT1 -0.37 -6.44 -0.33 4.02e-10 Methotrexate-induced interstitial lung disease in rheumatoid arthritis; LIHC cis rs2108622 0.711 rs113343664 chr19:15978993 G/C cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs62458065 0.513 rs9655340 chr7:32535920 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.74 7.39 0.37 1.17e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs2559856 0.967 rs3809260 chr12:102091017 G/T cg12924262 chr12:102091054 CHPT1 0.49 7.71 0.38 1.39e-13 Blood protein levels; LIHC cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg16145915 chr7:1198662 ZFAND2A 0.36 9.2 0.45 3.52e-18 Longevity;Endometriosis; LIHC cis rs2274273 0.870 rs7153612 chr14:55788762 T/C cg01864836 chr14:55583639 NA -0.37 -6.56 -0.33 1.97e-10 Protein biomarker; LIHC cis rs3806843 0.676 rs778593 chr5:140027216 T/C cg19875535 chr5:140030758 IK -0.43 -7.05 -0.36 9.96e-12 Depressive symptoms (multi-trait analysis); LIHC cis rs904251 0.523 rs1776454 chr6:37482099 C/T cg08126542 chr6:37504118 NA -0.36 -6.04 -0.31 4.03e-9 Cognitive performance; LIHC cis rs6912958 0.559 rs6921504 chr6:88058972 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.59 11.11 0.52 1.06e-24 Monocyte percentage of white cells; LIHC cis rs763014 0.966 rs35642938 chr16:642249 T/C cg00908189 chr16:619842 PIGQ 0.8 13.28 0.58 9.42e-33 Height; LIHC cis rs561341 0.769 rs7217004 chr17:30178092 A/G cg13647721 chr17:30228624 UTP6 -0.78 -6.61 -0.34 1.5e-10 Hip circumference adjusted for BMI; LIHC cis rs155076 1.000 rs155076 chr13:21870114 A/G cg14456004 chr13:21872349 NA -1.23 -12.92 -0.57 2.23e-31 White matter hyperintensity burden; LIHC trans rs6951245 0.554 rs10270249 chr7:1151886 G/T cg13565492 chr6:43139072 SRF -0.78 -7.24 -0.36 2.9e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs142472947 1 rs142472947 chr1:8520487 AAAG/A cg25722041 chr1:8623473 RERE 0.42 6.12 0.31 2.53e-9 White blood cell count; LIHC cis rs3862260 0.509 rs3862262 chr1:120161841 G/T cg16322792 chr1:120165303 ZNF697 0.53 9.74 0.47 5.95e-20 Systemic lupus erythematosus; LIHC cis rs7772486 0.875 rs2814872 chr6:146310234 T/C cg13319975 chr6:146136371 FBXO30 -0.39 -6.3 -0.32 9.41e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3768617 0.510 rs1886499 chr1:183095024 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs7582720 1.000 rs72934751 chr2:203747522 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs17685 0.753 rs10264760 chr7:75749694 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.2 -0.32 1.6e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs921968 0.608 rs11678428 chr2:219352598 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.58 0.42 3.48e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs7617773 0.780 rs35297395 chr3:48342882 C/T cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs6430585 0.583 rs2322813 chr2:136582809 A/G cg07305463 chr2:136567211 LCT -0.39 -5.72 -0.3 2.32e-8 Corneal structure; LIHC cis rs858239 0.601 rs1034963 chr7:23148473 T/C cg23682824 chr7:23144976 KLHL7 0.47 7.13 0.36 6.05e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs782590 0.935 rs782649 chr2:55860308 T/C cg18811423 chr2:55921094 PNPT1 0.99 15.96 0.65 2.94e-43 Metabolic syndrome; LIHC cis rs2625529 0.713 rs16956634 chr15:72552243 C/G cg16672083 chr15:72433130 SENP8 0.31 5.76 0.3 1.85e-8 Red blood cell count; LIHC cis rs9635231 1 rs9635231 chr14:55887703 C/T cg13175173 chr14:55914753 NA -0.31 -7.0 -0.35 1.39e-11 Pediatric bone mineral density (femoral neck); LIHC cis rs72781680 0.846 rs72782114 chr2:24025740 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.66 0.38 1.95e-13 Lymphocyte counts; LIHC cis rs1816752 1.000 rs1816752 chr13:24980949 A/G cg22771759 chr13:24902376 NA 0.36 6.86 0.35 3.16e-11 Obesity-related traits; LIHC cis rs12908161 1.000 rs62019469 chr15:85321220 T/C cg12863693 chr15:85201151 NMB 0.44 6.33 0.32 7.52e-10 Schizophrenia; LIHC cis rs5769765 1.000 rs4597652 chr22:50270570 A/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs1799949 0.628 rs4474733 chr17:41433660 G/T cg23758822 chr17:41437982 NA 0.86 14.39 0.61 4.89e-37 Menopause (age at onset); LIHC cis rs7937682 0.889 rs1789359 chr11:111475995 T/A cg09085632 chr11:111637200 PPP2R1B -0.9 -10.96 -0.51 3.76e-24 Primary sclerosing cholangitis; LIHC cis rs9916302 0.861 rs7503514 chr17:37669884 G/C cg03013999 chr17:37608204 MED1 0.35 5.74 0.3 2.08e-8 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.954 rs7656252 chr4:120404268 T/C cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.65e-29 Corneal astigmatism; LIHC cis rs11122272 0.735 rs2749709 chr1:231530476 G/T cg06096015 chr1:231504339 EGLN1 0.5 9.29 0.45 1.91e-18 Hemoglobin concentration; LIHC cis rs8180040 0.726 rs11130112 chr3:47024495 G/T cg16586182 chr3:47516702 SCAP -0.44 -7.88 -0.39 4.46e-14 Colorectal cancer; LIHC trans rs2727020 0.729 rs10839283 chr11:49490943 T/C cg18944383 chr4:111397179 ENPEP -0.32 -7.69 -0.38 1.58e-13 Coronary artery disease; LIHC cis rs2839186 0.934 rs2839194 chr21:47699437 T/G cg09417038 chr21:47716443 C21orf57 -0.5 -7.36 -0.37 1.35e-12 Testicular germ cell tumor; LIHC cis rs10916814 0.632 rs10916818 chr1:20897425 C/T cg24502330 chr1:20914028 CDA -0.31 -6.82 -0.35 4.1e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg08677398 chr8:58056175 NA 0.41 6.25 0.32 1.25e-9 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.38 0.45 9.22e-19 Bipolar disorder; LIHC cis rs1023500 0.573 rs6002592 chr22:42476754 A/C cg04733989 chr22:42467013 NAGA -0.66 -9.69 -0.46 8.66e-20 Schizophrenia; LIHC cis rs1707322 1.000 rs3922887 chr1:46473802 A/G cg06784218 chr1:46089804 CCDC17 0.37 6.65 0.34 1.14e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs9486715 1.000 rs9486725 chr6:97061159 C/T cg18709589 chr6:96969512 KIAA0776 -0.37 -6.45 -0.33 3.8e-10 Headache; LIHC cis rs35110281 0.837 rs2838343 chr21:45078035 C/T cg04455712 chr21:45112962 RRP1B 0.44 7.62 0.38 2.57e-13 Mean corpuscular volume; LIHC cis rs3784262 0.669 rs6493981 chr15:58352923 T/C cg12031962 chr15:58353849 ALDH1A2 -0.26 -5.73 -0.3 2.25e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg00960700 chr17:80709150 TBCD 0.36 5.83 0.3 1.26e-8 Glycated hemoglobin levels; LIHC cis rs769267 0.896 rs2315610 chr19:19597240 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.04 0.31 3.91e-9 Tonsillectomy; LIHC cis rs15676 0.947 rs7854319 chr9:131567995 G/A cg13708974 chr9:131466143 PKN3 -0.39 -5.86 -0.3 1.08e-8 Blood metabolite levels; LIHC cis rs2404602 0.655 rs3829489 chr15:77223256 A/C cg23625390 chr15:77176239 SCAPER 0.36 5.84 0.3 1.25e-8 Blood metabolite levels; LIHC cis rs9733 0.596 rs72702504 chr1:150635374 G/C cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs875971 0.862 rs7783779 chr7:65796626 A/G cg11764359 chr7:65958608 NA -0.77 -13.25 -0.58 1.25e-32 Aortic root size; LIHC cis rs2012796 0.743 rs61986598 chr14:81856865 G/A cg23690444 chr14:81902736 NA -0.44 -6.2 -0.32 1.6e-9 Night sleep phenotypes; LIHC cis rs2832191 0.791 rs2832182 chr21:30481612 G/A cg24692254 chr21:30365293 RNF160 -0.7 -12.91 -0.57 2.54e-31 Dental caries; LIHC cis rs7659604 0.967 rs34949254 chr4:122664344 G/A cg19748678 chr4:122722346 EXOSC9 0.37 6.3 0.32 9.24e-10 Type 2 diabetes; LIHC cis rs208520 0.661 rs7747492 chr6:66857788 A/T cg07460842 chr6:66804631 NA -0.79 -8.85 -0.43 4.67e-17 Exhaled nitric oxide output; LIHC cis rs875971 1.000 rs6460292 chr7:65810075 G/A cg11764359 chr7:65958608 NA -0.91 -16.91 -0.67 4.78e-47 Aortic root size; LIHC cis rs16958440 0.867 rs76558586 chr18:44737613 C/T cg17192377 chr18:44677553 HDHD2 0.92 8.61 0.42 2.67e-16 Sitting height ratio; LIHC cis rs60871478 0.947 rs62432255 chr7:804219 G/A cg27478167 chr7:817139 HEATR2 -0.41 -5.83 -0.3 1.32e-8 Cerebrospinal P-tau181p levels; LIHC cis rs10256972 0.967 rs1881122 chr7:1040946 A/T cg23978390 chr7:1156363 C7orf50 0.53 8.14 0.4 7.65e-15 Longevity;Endometriosis; LIHC cis rs12142240 0.698 rs66516678 chr1:46810112 G/T cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs4689592 0.503 rs66885632 chr4:7053738 T/C cg06697600 chr4:7070879 GRPEL1 0.63 9.5 0.46 3.8e-19 Monocyte percentage of white cells; LIHC cis rs12908161 1.000 rs12899981 chr15:85302373 G/A cg12863693 chr15:85201151 NMB 0.45 6.36 0.33 6.39e-10 Schizophrenia; LIHC cis rs6570726 0.791 rs6918814 chr6:145906028 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.3 0.45 1.69e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.966 rs17476234 chr3:47326298 G/A cg27129171 chr3:47204927 SETD2 -0.64 -10.72 -0.5 2.61e-23 Colorectal cancer; LIHC cis rs9733 0.565 rs11804276 chr1:150685761 T/A cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs4975616 0.869 rs401681 chr5:1322087 C/T cg06550200 chr5:1325588 CLPTM1L -0.53 -8.87 -0.43 4.21e-17 Lung cancer; LIHC cis rs10927875 0.632 rs10927863 chr1:16165247 C/A cg07117364 chr1:16154769 NA -0.39 -7.02 -0.35 1.19e-11 Dilated cardiomyopathy; LIHC cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg22963979 chr7:1858916 MAD1L1 -0.38 -5.91 -0.3 8.24e-9 Bipolar disorder and schizophrenia; LIHC trans rs10242455 0.571 rs7805661 chr7:99171522 A/C cg09045935 chr12:6379348 NA 0.93 8.0 0.4 2e-14 Blood metabolite levels; LIHC cis rs56235845 0.964 rs11741640 chr5:176792743 G/A cg16006841 chr5:176797999 RGS14 0.84 12.79 0.57 6.97e-31 Hemoglobin concentration;Hematocrit; LIHC cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg00149659 chr3:10157352 C3orf10 0.69 7.07 0.36 8.52e-12 Alzheimer's disease; LIHC cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg15534755 chr11:117069859 TAGLN 0.36 6.13 0.31 2.41e-9 Blood protein levels; LIHC cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg14983838 chr19:29218262 NA 0.49 7.62 0.38 2.5e-13 Methadone dose in opioid dependence; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg09396068 chr15:22940794 CYFIP1 0.48 6.59 0.34 1.62e-10 Hip circumference; LIHC cis rs2637266 0.739 rs2395404 chr10:78380513 G/T cg18941641 chr10:78392320 NA 0.3 6.39 0.33 5.46e-10 Pulmonary function; LIHC cis rs1577917 1.000 rs34281561 chr6:86701872 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.59 -0.34 1.66e-10 Response to antipsychotic treatment; LIHC trans rs1814175 0.817 rs7929173 chr11:49944007 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg14280964 chr1:37940281 ZC3H12A -0.41 -6.44 -0.33 4.14e-10 Eotaxin levels; LIHC cis rs2072499 0.900 rs2248080 chr1:156195971 T/A cg24450063 chr1:156163899 SLC25A44 1.02 16.93 0.68 3.86e-47 Testicular germ cell tumor; LIHC cis rs12594515 1.000 rs58368732 chr15:45990531 G/C cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.86e-12 Waist circumference;Weight; LIHC cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg18252515 chr7:66147081 NA -1.24 -16.13 -0.66 6.34e-44 Diabetic kidney disease; LIHC cis rs611744 0.967 rs596245 chr8:109240822 G/A cg21045802 chr8:109455806 TTC35 0.5 8.68 0.43 1.6e-16 Dupuytren's disease; LIHC cis rs1538970 0.924 rs4660851 chr1:45843810 A/T cg05343316 chr1:45956843 TESK2 0.53 8.0 0.4 2e-14 Platelet count; LIHC cis rs67311347 1.000 rs4973878 chr3:40407565 C/T cg09455208 chr3:40491958 NA 0.33 6.55 0.33 2.07e-10 Renal cell carcinoma; LIHC cis rs7223966 1.000 rs8075521 chr17:61804954 C/T cg05941027 chr17:61774174 LIMD2 0.36 7.54 0.38 4.22e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg26119090 chr2:26468346 HADHA;HADHB -1.11 -15.49 -0.64 2.29e-41 Gut microbiome composition (summer); LIHC cis rs1577917 1.000 rs35797755 chr6:86706554 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -9.77 -0.47 4.66e-20 Response to antipsychotic treatment; LIHC cis rs798554 0.797 rs798497 chr7:2795957 A/G cg19717773 chr7:2847554 GNA12 -0.4 -6.47 -0.33 3.41e-10 Height; LIHC cis rs7903847 0.596 rs9787426 chr10:99155327 A/G cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.53e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs8016982 0.633 rs72695758 chr14:81720146 T/C cg01989461 chr14:81687754 GTF2A1 0.69 13.61 0.59 5.32e-34 Schizophrenia; LIHC cis rs3857067 0.836 rs12501138 chr4:95098444 T/A cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.58 -0.38 3.33e-13 QT interval; LIHC cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg03452623 chr4:187889614 NA -0.31 -7.79 -0.39 7.95e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs1865760 0.566 rs9379825 chr6:26083871 C/A cg18357526 chr6:26021779 HIST1H4A 0.45 6.54 0.33 2.22e-10 Height; LIHC trans rs561341 1.000 rs2470267 chr17:30274132 G/A cg20587970 chr11:113659929 NA -1.23 -10.44 -0.49 2.51e-22 Hip circumference adjusted for BMI; LIHC cis rs11148252 0.595 rs9526974 chr13:53251040 C/G cg12458913 chr13:53173898 NA 0.45 7.22 0.36 3.36e-12 Lewy body disease; LIHC cis rs2832191 0.903 rs11700687 chr21:30486767 A/G cg08807101 chr21:30365312 RNF160 -0.59 -9.19 -0.45 3.81e-18 Dental caries; LIHC trans rs637571 0.584 rs7107912 chr11:65603252 G/A cg17712092 chr4:129076599 LARP1B -0.68 -10.07 -0.48 4.66e-21 Eosinophil percentage of white cells; LIHC cis rs1568889 0.938 rs11601602 chr11:28233768 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.51 6.88 0.35 2.79e-11 Bipolar disorder; LIHC cis rs7944735 0.508 rs11819955 chr11:47539208 A/G cg20307385 chr11:47447363 PSMC3 -0.54 -6.16 -0.32 2.09e-9 Intraocular pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18350866 chr20:39766189 PLCG1 -0.46 -6.03 -0.31 4.14e-9 Pancreatic cancer; LIHC cis rs7940866 0.834 rs1594821 chr11:130835883 C/T cg12179176 chr11:130786555 SNX19 0.61 8.98 0.44 1.91e-17 Schizophrenia; LIHC cis rs13108904 0.934 rs13134106 chr4:1302902 A/G cg13395646 chr4:1353034 KIAA1530 -0.67 -9.52 -0.46 3.21e-19 Obesity-related traits; LIHC cis rs1046896 0.553 rs2292965 chr17:80900645 G/A cg02711726 chr17:80685570 FN3KRP -0.41 -7.46 -0.37 7.13e-13 Glycated hemoglobin levels; LIHC cis rs1997103 0.954 rs1997099 chr7:55405540 T/C cg17469321 chr7:55412551 NA 0.48 7.09 0.36 7.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2948294 0.588 rs4840913 chr8:8116906 A/C cg08975724 chr8:8085496 FLJ10661 0.36 6.04 0.31 4.01e-9 Red cell distribution width; LIHC cis rs9611519 0.894 rs4821998 chr22:41468273 C/G cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.14e-14 Neuroticism; LIHC cis rs4908768 0.906 rs11584261 chr1:8560366 C/A cg20416874 chr1:8611966 RERE 0.57 8.86 0.43 4.3e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7044106 0.762 rs10491783 chr9:123450155 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.78 0.39 8.89e-14 Hip circumference adjusted for BMI; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23209537 chr7:5463409 TNRC18 0.48 6.71 0.34 8.03e-11 Lung function (FEV1/FVC); LIHC cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs10838687 0.610 rs4647737 chr11:47253244 T/G cg25783544 chr11:47291846 MADD 0.46 5.77 0.3 1.73e-8 Proinsulin levels; LIHC cis rs1577917 0.771 rs10944133 chr6:86358984 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -12.56 -0.56 5.38e-30 Response to antipsychotic treatment; LIHC cis rs2635047 0.967 rs2576056 chr18:44675462 G/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.46 6.17 0.32 1.94e-9 Educational attainment; LIHC cis rs7582720 1.000 rs72936882 chr2:203794439 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs539514 0.627 rs9544035 chr13:76293789 C/T cg04757411 chr13:76259545 LMO7 -0.47 -8.19 -0.4 5.28e-15 Type 1 diabetes; LIHC cis rs7255374 0.566 rs11666982 chr19:41531368 T/G cg27089200 chr19:41531976 NA 0.35 5.73 0.3 2.17e-8 DDT metabolite (p,p'-DDE levels); LIHC cis rs2408955 0.542 rs7975632 chr12:48443048 C/T cg21466736 chr12:48725269 NA -0.64 -9.37 -0.45 1.03e-18 Glycated hemoglobin levels; LIHC cis rs12286929 0.668 rs17304149 chr11:115049180 C/T cg04055981 chr11:115044050 NA 0.53 8.11 0.4 9.16e-15 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1451375 0.572 rs4948205 chr7:50557774 G/A cg14593290 chr7:50529359 DDC -0.61 -10.04 -0.48 5.71e-21 Malaria; LIHC cis rs10464366 0.571 rs4723825 chr7:39157627 G/C cg20302533 chr7:39170763 POU6F2 0.38 6.95 0.35 1.8e-11 IgG glycosylation; LIHC cis rs801193 1.000 rs3778909 chr7:66255646 G/C cg11764359 chr7:65958608 NA 0.71 10.6 0.5 6.78e-23 Aortic root size; LIHC cis rs9325144 0.560 rs13377717 chr12:38639474 T/A cg26384229 chr12:38710491 ALG10B -0.47 -7.26 -0.37 2.57e-12 Morning vs. evening chronotype; LIHC cis rs1801251 1.000 rs13004406 chr2:233584557 A/T cg25237894 chr2:233734115 C2orf82 -0.55 -10.65 -0.5 4.68e-23 Coronary artery disease; LIHC trans rs1945213 0.659 rs11227133 chr11:55836620 T/C cg03929089 chr4:120376271 NA 0.53 6.8 0.35 4.54e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs332507 0.830 rs2173852 chr3:124420102 C/G cg05980111 chr3:124395277 KALRN -0.42 -6.56 -0.33 1.96e-10 Plateletcrit; LIHC cis rs1005277 0.579 rs1740749 chr10:38521646 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8077889 0.917 rs72836553 chr17:41909851 A/G cg26893861 chr17:41843967 DUSP3 0.99 10.76 0.5 1.9e-23 Triglycerides; LIHC cis rs5753037 0.838 rs140149 chr22:30185613 C/T cg01021169 chr22:30184971 ASCC2 -0.35 -6.61 -0.34 1.49e-10 Type 1 diabetes; LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs2404602 0.647 rs12898810 chr15:76904738 T/C cg23625390 chr15:77176239 SCAPER -0.52 -8.51 -0.42 5.44e-16 Blood metabolite levels; LIHC cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg00166722 chr3:10149974 C3orf24 0.46 5.77 0.3 1.76e-8 Alzheimer's disease; LIHC cis rs9322817 0.691 rs2486136 chr6:105285759 C/T cg02098413 chr6:105308735 HACE1 0.45 8.41 0.41 1.16e-15 Thyroid stimulating hormone; LIHC cis rs4407350 1.000 rs4373014 chr22:44922424 C/T cg26276947 chr22:44892394 LDOC1L 0.34 6.36 0.33 6.45e-10 Intelligence (multi-trait analysis); LIHC cis rs7845219 0.544 rs9643351 chr8:95917290 C/T cg13393036 chr8:95962371 TP53INP1 -0.31 -5.89 -0.3 9.33e-9 Type 2 diabetes; LIHC cis rs9902453 0.845 rs7221516 chr17:28232506 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 14.0 0.6 1.67e-35 Coffee consumption (cups per day); LIHC cis rs12594515 1.000 rs11070467 chr15:45985001 C/T cg01629716 chr15:45996671 NA -0.51 -9.53 -0.46 3.07e-19 Waist circumference;Weight; LIHC cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg19454999 chr17:41278357 BRCA1;NBR2 -0.42 -6.08 -0.31 3.17e-9 Menopause (age at onset); LIHC cis rs12474201 0.928 rs17822019 chr2:46934505 T/C cg06386533 chr2:46925753 SOCS5 0.73 8.16 0.4 6.28e-15 Height; LIHC cis rs763121 0.853 rs35522482 chr22:39063015 C/A cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs8180040 0.966 rs9683033 chr3:47489820 C/T cg27129171 chr3:47204927 SETD2 0.56 9.57 0.46 2.3e-19 Colorectal cancer; LIHC cis rs6960043 0.818 rs10238161 chr7:15053827 A/T cg19272540 chr7:15055459 NA 0.26 7.16 0.36 4.98e-12 Type 2 diabetes; LIHC cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg25894440 chr7:65020034 NA 0.4 6.34 0.32 7.12e-10 Calcium levels; LIHC cis rs11583043 0.918 rs17525451 chr1:101422409 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.48 5.8 0.3 1.48e-8 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs3741404 0.825 rs11603384 chr11:63949095 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.98 16.53 0.67 1.58e-45 Platelet count; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg21842944 chr7:98985712 ARPC1B 0.48 6.17 0.32 1.97e-9 Hip circumference; LIHC cis rs6964587 0.967 rs12531966 chr7:91765840 A/G cg17063962 chr7:91808500 NA 1.03 20.37 0.74 5.87e-61 Breast cancer; LIHC cis rs56235845 0.694 rs11738681 chr5:176761535 A/G cg16006841 chr5:176797999 RGS14 0.56 7.41 0.37 9.92e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs6942756 0.531 rs9649530 chr7:128927406 G/A cg02491457 chr7:128862824 NA 0.49 7.56 0.38 3.63e-13 White matter hyperintensity burden; LIHC cis rs3862030 0.720 rs7341995 chr10:104223831 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.37 -0.37 1.26e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs7599312 0.534 rs7607373 chr2:213409719 G/A cg16329650 chr2:213403929 ERBB4 0.59 7.05 0.36 1.02e-11 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs911119 0.955 rs4815224 chr20:23594112 C/G cg16589663 chr20:23618590 CST3 0.76 7.76 0.39 9.94e-14 Chronic kidney disease; LIHC cis rs1008375 1.000 rs28545485 chr4:17645376 C/T cg16339924 chr4:17578868 LAP3 0.44 6.28 0.32 1.04e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg18279126 chr7:2041391 MAD1L1 0.36 6.0 0.31 5.13e-9 Bipolar disorder and schizophrenia; LIHC cis rs344364 0.511 rs1657144 chr16:1963989 C/A cg26897989 chr16:1907736 C16orf73 -0.51 -5.96 -0.31 6.37e-9 Glomerular filtration rate in chronic kidney disease; LIHC cis rs10791097 0.690 rs12284487 chr11:130729705 T/C cg14779329 chr11:130786720 SNX19 0.38 5.87 0.3 1.05e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.93 0.57 2.1e-31 Prudent dietary pattern; LIHC cis rs4663866 1.000 rs4663300 chr2:239181491 T/C cg16914508 chr2:239161102 PER2 0.8 5.9 0.3 8.86e-9 Irritable bowel syndrome; LIHC cis rs4819052 0.851 rs35560973 chr21:46662573 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.48 6.91 0.35 2.39e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs55665837 0.502 rs4757269 chr11:14836192 A/C cg00085434 chr11:14927489 NA 0.41 5.93 0.31 7.3e-9 Vitamin D levels; LIHC cis rs4129767 0.869 rs4969142 chr17:76398304 G/A cg02836325 chr17:76403955 PGS1 0.34 6.72 0.34 7.49e-11 HDL cholesterol; LIHC cis rs6840360 0.615 rs66852535 chr4:152472227 C/A cg22705602 chr4:152727874 NA -0.33 -6.5 -0.33 2.86e-10 Intelligence (multi-trait analysis); LIHC cis rs4423214 0.959 rs11606033 chr11:71154204 A/G cg05163923 chr11:71159392 DHCR7 0.9 14.34 0.61 7.71e-37 Vitamin D levels; LIHC trans rs11083475 1.000 rs1808382 chr19:39151034 G/T cg17791936 chr11:118902213 SLC37A4 -0.38 -6.04 -0.31 3.95e-9 Heart rate; LIHC cis rs10751667 0.666 rs10902249 chr11:958566 C/T cg10932868 chr11:921992 NA -0.38 -7.13 -0.36 6e-12 Alzheimer's disease (late onset); LIHC cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg23782820 chr8:58130467 NA 0.37 5.94 0.31 6.89e-9 Developmental language disorder (linguistic errors); LIHC cis rs6089584 0.587 rs3787423 chr20:60555485 G/A cg06108461 chr20:60628389 TAF4 -0.52 -6.83 -0.35 3.84e-11 Body mass index; LIHC cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg10360323 chr17:41437877 NA 0.41 6.17 0.32 1.97e-9 Menopause (age at onset); LIHC cis rs11030122 0.702 rs10835399 chr11:3989182 G/A cg18678763 chr11:4115507 RRM1 -0.57 -8.45 -0.42 8.23e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs3924048 0.559 rs4580 chr1:12628188 T/C cg00291366 chr1:12616550 NA 0.36 7.31 0.37 1.86e-12 Optic cup area; LIHC cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg00166722 chr3:10149974 C3orf24 0.52 6.02 0.31 4.54e-9 Alzheimer's disease; LIHC cis rs7647973 0.961 rs4955443 chr3:49286618 T/G cg07636037 chr3:49044803 WDR6 0.51 6.5 0.33 2.78e-10 Menarche (age at onset); LIHC cis rs7945705 0.818 rs4929916 chr11:8824996 C/T cg12365402 chr11:9010492 NRIP3 0.23 5.93 0.31 7.3e-9 Hemoglobin concentration; LIHC cis rs7945705 0.902 rs7479407 chr11:9023421 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.41 6.71 0.34 7.97e-11 Hemoglobin concentration; LIHC cis rs9660992 0.573 rs12126439 chr1:205200720 C/T cg21545522 chr1:205238299 TMCC2 0.37 7.1 0.36 7.18e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs208520 0.545 rs10944874 chr6:66752080 C/T cg07460842 chr6:66804631 NA -0.84 -14.93 -0.63 3.84e-39 Exhaled nitric oxide output; LIHC cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs12611088 0.600 rs2261316 chr19:44030998 A/G cg13740135 chr19:44006432 PHLDB3 0.42 6.3 0.32 9.38e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11809123 chr19:1584870 MBD3 0.43 6.43 0.33 4.34e-10 Immature fraction of reticulocytes; LIHC trans rs7246657 0.943 rs4802136 chr19:37849811 T/A cg10208301 chr11:6592745 DNHD1 0.47 6.89 0.35 2.75e-11 Coronary artery calcification; LIHC cis rs1387259 0.931 rs1107654 chr12:48681097 T/G cg21466736 chr12:48725269 NA -0.71 -10.96 -0.51 3.57e-24 Obstructive sleep apnea trait (apnea hypopnea index); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg11850622 chr4:159593397 ETFDH;C4orf46 -0.44 -6.29 -0.32 9.73e-10 Alopecia areata; LIHC cis rs854765 0.647 rs2056842 chr17:18009028 C/T cg04398451 chr17:18023971 MYO15A -0.69 -11.75 -0.54 5.45e-27 Total body bone mineral density; LIHC cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg13770153 chr20:60521292 NA 0.62 13.63 0.59 4.45e-34 Obesity-related traits; LIHC trans rs10213084 1.000 rs10212996 chr4:147501301 A/G cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs9912789 0.744 rs9893755 chr17:79187432 C/T cg09314803 chr17:79180344 AZI1 0.36 6.44 0.33 4.14e-10 Frontotemporal dementia; LIHC cis rs10857712 0.754 rs1052582 chr10:135233840 C/G cg01444801 chr10:135216882 MTG1 -0.64 -9.43 -0.45 6.22e-19 Systemic lupus erythematosus; LIHC cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg26818010 chr10:134567672 INPP5A -0.78 -9.56 -0.46 2.43e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4285214 0.715 rs12515071 chr5:124031011 C/T cg15082166 chr5:124005151 ZNF608 0.41 5.86 0.3 1.08e-8 Survival in pancreatic cancer; LIHC cis rs7552404 0.731 rs10873788 chr1:76367857 A/C cg03433033 chr1:76189801 ACADM 0.46 6.28 0.32 1.02e-9 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs7818688 0.697 rs11779698 chr8:95979764 C/G cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6964587 0.869 rs406 chr7:91546526 C/A cg17063962 chr7:91808500 NA -0.98 -18.41 -0.71 4.45e-53 Breast cancer; LIHC trans rs4650994 1.000 rs17361251 chr1:178520577 C/A cg05059571 chr16:84539110 KIAA1609 -0.38 -6.36 -0.33 6.41e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9517302 0.847 rs9517300 chr13:99095057 T/C cg07423050 chr13:99094983 FARP1 -0.37 -5.82 -0.3 1.33e-8 Obesity-related traits; LIHC cis rs523522 0.924 rs11065150 chr12:120958875 T/G cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs13256369 1.000 rs4841017 chr8:8577093 A/G cg17143192 chr8:8559678 CLDN23 0.69 11.25 0.52 3.33e-25 Obesity-related traits; LIHC cis rs1816752 0.935 rs3816219 chr13:25017133 C/T cg02811702 chr13:24901961 NA 0.25 6.22 0.32 1.46e-9 Obesity-related traits; LIHC cis rs7089973 0.604 rs11196929 chr10:116582080 G/C cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg24209194 chr3:40518798 ZNF619 0.48 7.12 0.36 6.53e-12 Renal cell carcinoma; LIHC cis rs6964587 0.692 rs2374550 chr7:91820987 A/G cg17063962 chr7:91808500 NA 0.67 12.14 0.55 1.96e-28 Breast cancer; LIHC cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg12463550 chr7:65579703 CRCP -0.66 -6.89 -0.35 2.75e-11 Diabetic kidney disease; LIHC cis rs7246657 0.882 rs13345148 chr19:37819631 A/G cg23950597 chr19:37808831 NA -0.44 -5.87 -0.3 1.02e-8 Coronary artery calcification; LIHC trans rs1945213 0.694 rs9888298 chr11:55865704 T/C cg15704280 chr7:45808275 SEPT13 0.6 7.71 0.38 1.39e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs9814567 1.000 rs12637751 chr3:134266124 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg04944784 chr2:26401820 FAM59B -0.7 -9.23 -0.45 2.81e-18 Gut microbiome composition (summer); LIHC cis rs559928 0.548 rs11231713 chr11:63931849 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 6.63 0.34 1.32e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs1707322 1.000 rs7538978 chr1:46505054 C/T cg06784218 chr1:46089804 CCDC17 -0.35 -6.32 -0.32 8.05e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7511006 1.000 rs17836662 chr22:50672154 A/G cg16473166 chr22:50639996 SELO -0.54 -7.84 -0.39 5.77e-14 Obesity-related traits; LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg11062466 chr8:58055876 NA 0.51 7.61 0.38 2.72e-13 Developmental language disorder (linguistic errors); LIHC cis rs2832191 0.716 rs9983051 chr21:30371890 C/T cg24692254 chr21:30365293 RNF160 0.85 15.2 0.63 3.27e-40 Dental caries; LIHC cis rs2832191 0.967 rs3787660 chr21:30520907 C/T cg24692254 chr21:30365293 RNF160 0.48 8.41 0.41 1.13e-15 Dental caries; LIHC cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg12310025 chr6:25882481 NA -0.47 -7.17 -0.36 4.57e-12 Height; LIHC cis rs4555082 0.718 rs2816619 chr14:105732551 G/C cg10792982 chr14:105748885 BRF1 0.5 6.56 0.33 2.05e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs2645694 0.626 rs12502590 chr4:77823642 G/A cg06046430 chr4:77819534 ANKRD56 0.49 6.52 0.33 2.58e-10 Emphysema distribution in smoking; LIHC cis rs826838 0.967 rs4768330 chr12:39129399 T/C cg13010199 chr12:38710504 ALG10B -0.41 -5.78 -0.3 1.66e-8 Heart rate; LIHC cis rs1448094 0.512 rs11117057 chr12:86248546 C/T cg02569458 chr12:86230093 RASSF9 0.47 6.27 0.32 1.12e-9 Major depressive disorder; LIHC cis rs427394 0.772 rs274689 chr5:6736215 G/C cg10857441 chr5:6722123 POLS -0.37 -6.4 -0.33 5.26e-10 Menopause (age at onset); LIHC trans rs800082 0.690 rs2575191 chr3:144279228 G/A cg24215973 chr2:240111563 HDAC4 0.48 7.29 0.37 2.23e-12 Smoking behavior; LIHC trans rs1005277 0.541 rs1740741 chr10:38515334 C/T cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.96e-11 Extrinsic epigenetic age acceleration; LIHC cis rs11098699 1.000 rs7670452 chr4:124184613 C/T cg09941581 chr4:124220074 SPATA5 0.3 5.72 0.3 2.37e-8 Mosquito bite size; LIHC cis rs801193 1.000 rs4717319 chr7:66242593 A/G cg00343986 chr7:65444356 GUSB 0.41 6.1 0.31 2.9e-9 Aortic root size; LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg13271783 chr10:134563150 INPP5A -0.56 -6.54 -0.33 2.23e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs6951245 0.554 rs35126802 chr7:1134842 C/T cg13565492 chr6:43139072 SRF -0.79 -7.32 -0.37 1.81e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3806843 0.735 rs2563335 chr5:140044292 A/C cg26395211 chr5:140044315 WDR55 -0.4 -5.77 -0.3 1.73e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs9425766 0.640 rs2208850 chr1:173831707 A/C cg06124660 chr1:173389066 NA -0.32 -5.87 -0.3 1.04e-8 Life satisfaction; LIHC cis rs6570726 0.935 rs380883 chr6:145822992 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.59 0.46 1.97e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs11583043 0.793 rs3903905 chr1:101420957 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.18 0.44 4.07e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2404602 0.583 rs12907668 chr15:76589767 A/T cg03037974 chr15:76606532 NA 0.9 23.3 0.78 1.43e-72 Blood metabolite levels; LIHC cis rs588177 0.613 rs3782101 chr11:64131280 A/G cg24431193 chr11:63883947 FLRT1;MACROD1 0.39 5.78 0.3 1.65e-8 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs74233809 0.901 rs17878846 chr10:104630412 A/T cg03493300 chr10:104813866 CNNM2 0.44 5.83 0.3 1.26e-8 Birth weight; LIHC cis rs10911251 0.546 rs10911267 chr1:183115323 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.43 0.49 2.6e-22 Colorectal cancer; LIHC cis rs780096 0.527 rs11127044 chr2:27740404 C/G cg27432699 chr2:27873401 GPN1 -0.6 -8.6 -0.42 2.93e-16 Total body bone mineral density; LIHC cis rs9768139 0.733 rs13309408 chr7:158122261 C/T cg06219351 chr7:158114137 PTPRN2 -0.21 -5.79 -0.3 1.6e-8 Calcium levels; LIHC cis rs6430585 0.583 rs9636213 chr2:136589278 G/A cg07169764 chr2:136633963 MCM6 -1.03 -16.18 -0.66 4.01e-44 Corneal structure; LIHC trans rs8073060 0.544 rs225244 chr17:33946581 A/G cg19694781 chr19:47549865 TMEM160 1.16 12.75 0.57 1e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs894734 0.535 rs7301643 chr12:54325796 G/T cg12374095 chr12:54320830 NA 0.45 7.07 0.36 8.92e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs12216125 0.801 rs56107510 chr6:25987436 C/A cg17691542 chr6:26056736 HIST1H1C 0.5 6.3 0.32 9.39e-10 Iron status biomarkers; LIHC trans rs2243480 1.000 rs316312 chr7:65596491 T/G cg10756647 chr7:56101905 PSPH 1.1 13.41 0.59 3.1e-33 Diabetic kidney disease; LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg06873352 chr17:61820015 STRADA 0.74 13.22 0.58 1.7e-32 Prudent dietary pattern; LIHC cis rs2455799 0.613 rs3856830 chr3:15806520 A/C cg12698662 chr3:15914712 MIR563 -0.4 -7.53 -0.38 4.69e-13 Mean platelet volume; LIHC cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg16325326 chr1:53192061 ZYG11B -0.5 -8.78 -0.43 8.15e-17 Monocyte count; LIHC cis rs7937890 0.904 rs7484197 chr11:14283654 C/T cg06199346 chr11:14280333 SPON1 -0.35 -5.75 -0.3 2e-8 Mitochondrial DNA levels; LIHC cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg17971929 chr21:40555470 PSMG1 -0.44 -6.72 -0.34 7.55e-11 Cognitive function; LIHC cis rs240764 0.717 rs1039032 chr6:101161931 T/C cg09795085 chr6:101329169 ASCC3 -0.47 -6.74 -0.34 6.59e-11 Neuroticism; LIHC cis rs10089 0.953 rs72794400 chr5:127516028 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.5 6.2 0.32 1.66e-9 Ileal carcinoids; LIHC cis rs8062405 0.964 rs9972768 chr16:28861734 A/C cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.632 rs4441050 chr11:111772506 C/T cg09085632 chr11:111637200 PPP2R1B 0.93 13.78 0.6 1.2e-34 Primary sclerosing cholangitis; LIHC cis rs2070488 1.000 rs1841777 chr3:38484819 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC cis rs13161895 1.000 rs3719 chr5:179435118 T/C cg02702477 chr5:179499311 RNF130 -0.75 -10.29 -0.49 7.91e-22 LDL cholesterol; LIHC trans rs2243480 1.000 rs6460261 chr7:65215580 T/C cg10756647 chr7:56101905 PSPH -1.11 -13.62 -0.59 4.91e-34 Diabetic kidney disease; LIHC cis rs1538970 0.851 rs61788285 chr1:45919234 A/C cg24296786 chr1:45957014 TESK2 -0.51 -7.34 -0.37 1.53e-12 Platelet count; LIHC cis rs9814567 0.762 rs13079012 chr3:134247706 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.58 7.31 0.37 1.96e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4700695 0.764 rs251277 chr5:65390177 A/G cg21114390 chr5:65439923 SFRS12 -0.46 -6.06 -0.31 3.66e-9 Facial morphology (factor 19); LIHC cis rs4919087 0.923 rs12357266 chr10:98978045 G/A cg25902810 chr10:99078978 FRAT1 0.64 9.26 0.45 2.37e-18 Monocyte count; LIHC cis rs3812111 0.809 rs1999659 chr6:116430382 G/A cg08036074 chr6:116424633 NT5DC1 -0.66 -11.79 -0.54 3.7e-27 Age-related macular degeneration; LIHC cis rs881375 0.967 rs1860824 chr9:123659339 G/T cg14580859 chr9:123691850 NA 0.38 6.47 0.33 3.3e-10 Rheumatoid arthritis; LIHC cis rs6847149 0.929 rs4698752 chr4:110780964 A/G cg07850274 chr4:110748770 RRH 0.41 6.05 0.31 3.72e-9 Exercise treadmill test traits; LIHC cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg18404041 chr3:52824283 ITIH1 -0.57 -9.66 -0.46 1.13e-19 Bipolar disorder; LIHC cis rs861020 0.630 rs685248 chr1:210008367 C/G cg05527609 chr1:210001259 C1orf107 0.45 6.27 0.32 1.08e-9 Orofacial clefts; LIHC cis rs4730250 0.802 rs77936580 chr7:106946343 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.88 -0.3 9.71e-9 Osteoarthritis; LIHC cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg18357526 chr6:26021779 HIST1H4A 0.58 8.01 0.4 1.85e-14 Blood metabolite levels; LIHC cis rs12477438 0.798 rs6740267 chr2:99561867 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.8 -10.19 -0.48 1.85e-21 Chronic sinus infection; LIHC cis rs1577917 0.771 rs6454486 chr6:86433587 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.38 6.74 0.34 6.68e-11 Response to antipsychotic treatment; LIHC cis rs4474465 1.000 rs7131199 chr11:78192148 T/G cg02023728 chr11:77925099 USP35 0.36 6.23 0.32 1.37e-9 Alzheimer's disease (survival time); LIHC cis rs1371867 0.846 rs1788196 chr8:101290088 C/T cg06002616 chr8:101225028 SPAG1 -0.35 -5.76 -0.3 1.85e-8 Atrioventricular conduction; LIHC cis rs1538970 0.884 rs781232 chr1:45890399 C/T cg24296786 chr1:45957014 TESK2 0.51 7.61 0.38 2.78e-13 Platelet count; LIHC cis rs7107174 0.892 rs2512548 chr11:77962116 A/G cg02023728 chr11:77925099 USP35 0.48 9.06 0.44 1.03e-17 Testicular germ cell tumor; LIHC cis rs765787 0.530 rs11636018 chr15:45539137 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.44 -0.37 8.09e-13 Uric acid levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01246405 chr11:3876562 STIM1 0.39 6.31 0.32 8.84e-10 Cognitive function; LIHC cis rs6582630 0.555 rs34145279 chr12:38405588 T/C cg26384229 chr12:38710491 ALG10B 0.84 10.51 0.49 1.45e-22 Drug-induced liver injury (flucloxacillin); LIHC cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg12292205 chr6:26970375 C6orf41 -0.43 -7.25 -0.36 2.82e-12 Schizophrenia; LIHC cis rs2839186 0.565 rs2839183 chr21:47687144 G/A cg12379764 chr21:47803548 PCNT 0.6 7.92 0.39 3.4e-14 Testicular germ cell tumor; LIHC cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg25072359 chr17:41440525 NA 0.41 6.48 0.33 3.19e-10 Menopause (age at onset); LIHC cis rs7772486 0.790 rs2265919 chr6:146221753 A/G cg23711669 chr6:146136114 FBXO30 0.63 11.0 0.51 2.65e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs11663156 1.000 rs1502214 chr18:50932056 T/A cg24270629 chr18:50823537 DCC -0.48 -6.64 -0.34 1.27e-10 Intelligence (multi-trait analysis); LIHC cis rs4407350 0.870 rs1894461 chr22:44911287 C/T cg04154583 chr22:44889756 LDOC1L 0.3 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs10503871 0.545 rs7828054 chr8:30509487 G/C cg26383811 chr8:30366931 RBPMS 0.38 5.88 0.3 9.5e-9 Metabolite levels (X-11787); LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg11060661 chr22:24314208 DDT;DDTL 0.57 8.98 0.44 1.88e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs17253792 0.822 rs28409547 chr14:56047826 C/T cg24579896 chr14:56047964 C14orf33;KTN1 0.7 5.82 0.3 1.38e-8 Putamen volume; LIHC cis rs10197940 0.967 rs4664423 chr2:152266311 T/C cg19508488 chr2:152266495 RIF1 0.74 12.59 0.56 4.03e-30 Lung cancer; LIHC cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg11062466 chr8:58055876 NA 0.4 5.97 0.31 6.07e-9 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.660 rs6460308 chr7:66084740 T/C cg14393609 chr7:65229607 NA -0.38 -6.03 -0.31 4.25e-9 Aortic root size; LIHC cis rs12188164 0.610 rs72711368 chr5:418839 C/T cg15640734 chr5:494837 SLC9A3 -0.37 -5.76 -0.3 1.9e-8 Cystic fibrosis severity; LIHC cis rs2070488 1.000 rs13089394 chr3:38446309 C/A cg24069376 chr3:38537580 EXOG 0.42 7.68 0.38 1.65e-13 Electrocardiographic conduction measures; LIHC cis rs6598955 0.756 rs10902723 chr1:26568542 T/C cg00852783 chr1:26633632 UBXN11 0.49 8.27 0.41 3.05e-15 Obesity-related traits; LIHC cis rs7618501 0.633 rs2353579 chr3:50027774 C/T cg21467203 chr3:49911342 NA -0.44 -7.99 -0.4 2.11e-14 Intelligence (multi-trait analysis); LIHC cis rs796364 0.806 rs74938253 chr2:201008386 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.66 -7.66 -0.38 1.96e-13 Schizophrenia; LIHC cis rs12971120 0.891 rs71359051 chr18:72169723 G/A cg26446133 chr18:72167187 CNDP2 -0.8 -14.87 -0.63 6.27e-39 Refractive error; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09623986 chr2:74753896 AUP1;DQX1 -0.41 -6.27 -0.32 1.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9513627 1.000 rs9582302 chr13:100125985 A/T cg25919922 chr13:100150906 NA -0.77 -6.7 -0.34 8.5e-11 Obesity-related traits; LIHC cis rs6076065 0.775 rs761723 chr20:23330720 A/G cg11657817 chr20:23433608 CST11 0.31 6.66 0.34 1.1e-10 Facial morphology (factor 15, philtrum width); LIHC cis rs12586317 0.620 rs10145433 chr14:35583333 G/A cg05294307 chr14:35346193 BAZ1A -0.46 -6.81 -0.35 4.32e-11 Psoriasis; LIHC cis rs1823913 1.000 rs6749232 chr2:192115052 C/G cg12404831 chr2:192114017 MYO1B -0.33 -6.57 -0.33 1.9e-10 Obesity-related traits; LIHC cis rs4474465 0.790 rs10793331 chr11:78270000 C/T cg27205649 chr11:78285834 NARS2 0.4 6.3 0.32 9.03e-10 Alzheimer's disease (survival time); LIHC cis rs17539620 0.624 rs62432743 chr6:154836214 T/G cg17771515 chr6:154831774 CNKSR3 0.58 6.43 0.33 4.28e-10 Lipoprotein (a) levels; LIHC cis rs1005277 0.563 rs2800550 chr10:38482929 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.27 -0.32 1.06e-9 Extrinsic epigenetic age acceleration; LIHC cis rs710216 0.571 rs11210772 chr1:43448499 A/G cg03128534 chr1:43423976 SLC2A1 -0.46 -6.07 -0.31 3.39e-9 Red cell distribution width; LIHC cis rs919433 0.519 rs700658 chr2:198655007 A/T cg10820045 chr2:198174542 NA 0.46 6.94 0.35 2.01e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2204008 0.744 rs12099650 chr12:38317140 C/G cg26384229 chr12:38710491 ALG10B 0.57 7.83 0.39 6.05e-14 Bladder cancer; LIHC cis rs2404602 0.647 rs2404600 chr15:77173557 C/T cg03037974 chr15:76606532 NA -0.59 -9.84 -0.47 2.75e-20 Blood metabolite levels; LIHC cis rs11718455 0.960 rs3843373 chr3:44011053 C/T cg08738300 chr3:44038990 NA -0.49 -8.08 -0.4 1.14e-14 Coronary artery disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06521774 chr1:38397588 INPP5B -0.5 -6.08 -0.31 3.15e-9 Systolic blood pressure; LIHC cis rs79976124 0.837 rs10944858 chr6:66646039 G/A cg07460842 chr6:66804631 NA 0.65 6.88 0.35 2.89e-11 Type 2 diabetes; LIHC cis rs2404602 0.684 rs12591622 chr15:76930655 A/T cg03037974 chr15:76606532 NA -0.6 -9.88 -0.47 2.04e-20 Blood metabolite levels; LIHC cis rs2832191 0.692 rs2245734 chr21:30359965 C/T cg08807101 chr21:30365312 RNF160 0.79 11.94 0.54 1.09e-27 Dental caries; LIHC cis rs7617773 0.746 rs6796343 chr3:48282021 C/A cg11946769 chr3:48343235 NME6 0.89 10.97 0.51 3.42e-24 Coronary artery disease; LIHC cis rs116248771 0.690 rs16847125 chr3:158417699 C/T cg16708174 chr3:158430962 RARRES1 0.47 6.28 0.32 1.03e-9 diarrhoeal disease at age 2; LIHC trans rs6446298 1.000 rs6446298 chr3:49860854 T/C cg21582582 chr3:182698605 DCUN1D1 0.49 6.46 0.33 3.55e-10 Intelligence (multi-trait analysis); LIHC cis rs11023332 0.617 rs1879888 chr11:14679247 A/G cg19336497 chr11:14380999 RRAS2 -0.35 -6.14 -0.32 2.28e-9 Adiponectin levels;Vitamin D levels; LIHC cis rs2336384 1.000 rs2878677 chr1:12053264 C/T cg13216073 chr1:12042593 MFN2 -0.41 -6.58 -0.34 1.81e-10 Platelet count; LIHC cis rs1577917 0.739 rs6922 chr6:86205323 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 11.84 0.54 2.49e-27 Response to antipsychotic treatment; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs758324 0.947 rs56081930 chr5:131235274 T/G cg06307176 chr5:131281290 NA -0.42 -6.15 -0.32 2.12e-9 Alzheimer's disease in APOE e4- carriers; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05908079 chr5:64065005 SDCCAG10;SFRS12IP1 -0.46 -6.63 -0.34 1.35e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs921968 0.643 rs508157 chr2:219435288 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.29 0.32 9.97e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1577917 0.958 rs12205492 chr6:86475976 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.75 -0.5 2.11e-23 Response to antipsychotic treatment; LIHC cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg06634786 chr22:41940651 POLR3H 0.83 8.94 0.44 2.53e-17 Vitiligo; LIHC cis rs9457247 0.602 rs2239827 chr6:167490945 G/A cg23791538 chr6:167370224 RNASET2 -0.47 -6.75 -0.34 6.49e-11 Crohn's disease; LIHC cis rs427394 0.582 rs274661 chr5:6704848 C/T cg10857441 chr5:6722123 POLS -0.36 -6.23 -0.32 1.38e-9 Menopause (age at onset); LIHC cis rs926392 0.896 rs7268772 chr20:37684501 A/G cg16355469 chr20:37678765 NA 0.37 6.02 0.31 4.38e-9 Dialysis-related mortality; LIHC cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg13607699 chr17:42295918 UBTF -0.46 -7.32 -0.37 1.81e-12 Total body bone mineral density; LIHC cis rs918629 0.567 rs6877329 chr5:95261538 C/G cg10483112 chr5:95245456 ELL2 -0.38 -7.17 -0.36 4.76e-12 IgG glycosylation; LIHC cis rs35306767 0.855 rs35825568 chr10:950760 C/T cg20503657 chr10:835505 NA 0.99 11.08 0.51 1.38e-24 Eosinophil percentage of granulocytes; LIHC cis rs2075371 1.000 rs2241335 chr7:133979368 C/T cg20476274 chr7:133979776 SLC35B4 0.74 12.55 0.56 5.72e-30 Mean platelet volume; LIHC cis rs7100689 0.622 rs1340379 chr10:82121455 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg24503407 chr1:205819492 PM20D1 0.62 8.64 0.42 2.22e-16 Menarche (age at onset); LIHC cis rs12497850 0.931 rs6791542 chr3:48787219 A/G cg06212747 chr3:49208901 KLHDC8B 0.58 7.7 0.38 1.52e-13 Parkinson's disease; LIHC cis rs9467773 0.967 rs6941022 chr6:26553531 T/C cg11502198 chr6:26597334 ABT1 0.45 6.56 0.33 1.97e-10 Intelligence (multi-trait analysis); LIHC cis rs992157 0.644 rs6741757 chr2:219182748 T/C cg00012203 chr2:219082015 ARPC2 0.76 10.76 0.5 1.88e-23 Colorectal cancer; LIHC cis rs17102423 0.652 rs4902361 chr14:65548470 G/T cg16583315 chr14:65563665 MAX -0.4 -8.1 -0.4 9.62e-15 Obesity-related traits; LIHC cis rs1707322 1.000 rs785510 chr1:46528618 T/C cg06784218 chr1:46089804 CCDC17 -0.4 -6.96 -0.35 1.7e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs80282103 0.867 rs17155821 chr10:1071701 A/G cg08668510 chr10:1095578 IDI1 0.65 6.67 0.34 1.06e-10 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.75 0.62 1.8e-38 Prudent dietary pattern; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19250764 chr7:66461952 TYW1;SBDS 0.42 6.34 0.32 7.13e-10 Lung function (FEV1/FVC); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23807559 chr17:71189217 COG1 -0.41 -6.18 -0.32 1.83e-9 Pancreatic cancer; LIHC cis rs9303401 0.614 rs12947982 chr17:57140301 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.4 0.56 2.05e-29 Cognitive test performance; LIHC cis rs57221529 0.713 rs12521091 chr5:590710 G/T cg16447950 chr5:562315 NA -0.49 -5.73 -0.3 2.19e-8 Lung disease severity in cystic fibrosis; LIHC cis rs10056811 0.538 rs4703645 chr5:74361140 A/G cg00601450 chr5:74908170 NA 0.52 6.05 0.31 3.73e-9 Coronary artery disease; LIHC cis rs523522 0.962 rs1050187 chr12:120902111 A/G cg27279351 chr12:120934652 DYNLL1 -0.65 -11.48 -0.53 5.07e-26 High light scatter reticulocyte count; LIHC cis rs7772486 0.558 rs62435775 chr6:146136415 G/C cg13319975 chr6:146136371 FBXO30 -0.56 -8.83 -0.43 5.67e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs9503598 0.714 rs11242859 chr6:3454032 G/A cg00476032 chr6:3446245 SLC22A23 0.45 8.68 0.43 1.6e-16 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs9921222 1.000 rs9921222 chr16:375782 A/G cg00101154 chr16:420108 MRPL28 0.49 6.99 0.35 1.47e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg26338869 chr17:61819248 STRADA 0.52 6.84 0.35 3.69e-11 Height; LIHC cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg16414030 chr3:133502952 NA -0.42 -6.55 -0.33 2.16e-10 Iron status biomarkers; LIHC cis rs644799 0.544 rs525087 chr11:95632266 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.58 8.03 0.4 1.62e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4891159 0.790 rs72975925 chr18:74143902 G/A cg24786174 chr18:74118243 ZNF516 -0.73 -13.07 -0.58 6.18e-32 Longevity; LIHC cis rs6912958 0.500 rs9342104 chr6:87798512 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.38 -6.02 -0.31 4.59e-9 Monocyte percentage of white cells; LIHC trans rs2727020 0.658 rs4980442 chr11:49445016 G/T cg18944383 chr4:111397179 ENPEP 0.25 6.22 0.32 1.45e-9 Coronary artery disease; LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg20295408 chr7:1910781 MAD1L1 -0.49 -7.13 -0.36 6.02e-12 Bipolar disorder and schizophrenia; LIHC cis rs9814567 0.896 rs2177602 chr3:134245866 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11958404 0.932 rs72816587 chr5:157434144 T/A cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC trans rs334353 0.785 rs334364 chr9:101929144 C/T cg06788856 chr17:1821969 NA -0.33 -6.18 -0.32 1.86e-9 Age-related macular degeneration; LIHC trans rs7668874 0.779 rs1430933 chr4:116809178 G/A cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs11122272 0.705 rs2808599 chr1:231533482 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.73e-19 Hemoglobin concentration; LIHC cis rs7208859 0.623 rs55638872 chr17:29149552 G/C cg14067834 chr17:29058358 SUZ12P 0.68 6.62 0.34 1.38e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9911578 1.000 rs1494977 chr17:56863064 C/T cg12560992 chr17:57184187 TRIM37 0.97 17.4 0.69 5.3e-49 Intelligence (multi-trait analysis); LIHC cis rs6088590 0.965 rs6058108 chr20:33288655 A/G cg06115741 chr20:33292138 TP53INP2 0.57 8.18 0.4 5.73e-15 Coronary artery disease; LIHC cis rs3857067 0.772 rs4692999 chr4:95107644 T/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.58 -0.38 3.29e-13 QT interval; LIHC cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs7659604 0.540 rs34445121 chr4:122710889 G/A cg19671926 chr4:122722719 EXOSC9 0.56 8.61 0.42 2.75e-16 Type 2 diabetes; LIHC cis rs881375 0.715 rs11794516 chr9:123640230 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.43 0.33 4.26e-10 Rheumatoid arthritis; LIHC cis rs1707322 0.721 rs4660883 chr1:46236098 C/T cg03146154 chr1:46216737 IPP 0.59 10.15 0.48 2.57e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11650776 1 rs11650776 chr17:37641402 G/A cg03013999 chr17:37608204 MED1 0.36 5.98 0.31 5.5e-9 Lung function (FEV1); LIHC trans rs5756813 0.688 rs8140207 chr22:38130459 G/T cg19894588 chr14:64061835 NA -0.61 -7.78 -0.39 8.85e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg13944838 chr5:179740914 GFPT2 -0.5 -7.17 -0.36 4.76e-12 Height; LIHC cis rs7208859 0.673 rs216411 chr17:28903493 T/C cg14067834 chr17:29058358 SUZ12P -0.6 -6.15 -0.32 2.15e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs1814175 0.645 rs28634872 chr11:50042175 T/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs2204008 0.837 rs73112346 chr12:38357606 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 2.97e-23 Bladder cancer; LIHC trans rs877282 0.853 rs11595507 chr10:756703 C/T cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs950776 0.518 rs2869055 chr15:78822388 G/C cg06917634 chr15:78832804 PSMA4 -0.63 -9.97 -0.47 1.05e-20 Sudden cardiac arrest; LIHC cis rs1775715 0.966 rs1639132 chr10:32301260 G/A cg14930904 chr10:32216787 ARHGAP12 -0.41 -7.23 -0.36 3.1e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs10540 1.000 rs71487292 chr11:486076 G/A cg03576123 chr11:487126 PTDSS2 -1.24 -8.92 -0.43 2.88e-17 Body mass index; LIHC cis rs9309473 0.528 rs6546820 chr2:73553397 G/A cg20560298 chr2:73613845 ALMS1 -0.46 -7.44 -0.37 8.39e-13 Metabolite levels; LIHC cis rs1506636 1.000 rs2215553 chr7:123318478 G/T cg03229431 chr7:123269106 ASB15 -0.61 -12.27 -0.55 6.39e-29 Plateletcrit;Platelet count; LIHC cis rs1789 0.653 rs13142069 chr4:15593692 C/T cg21123203 chr4:15471301 CC2D2A 0.39 6.54 0.33 2.22e-10 Blood protein levels; LIHC cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg25894440 chr7:65020034 NA 0.51 5.9 0.3 8.83e-9 Diabetic kidney disease; LIHC cis rs12701220 0.817 rs1058729 chr7:1087283 C/T cg04025307 chr7:1156635 C7orf50 0.46 6.18 0.32 1.81e-9 Bronchopulmonary dysplasia; LIHC cis rs17685 0.753 rs3757593 chr7:75678735 G/A cg16684958 chr7:75615977 POR -0.51 -8.48 -0.42 6.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17666538 0.535 rs896522 chr8:616991 A/G cg02524346 chr8:600233 NA 0.78 5.94 0.31 6.97e-9 IgG glycosylation; LIHC cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.74 -0.34 6.6e-11 Gut microbiome composition (summer); LIHC cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg12310025 chr6:25882481 NA -0.43 -6.47 -0.33 3.38e-10 Height; LIHC cis rs7666738 0.830 rs9992391 chr4:98916052 G/A cg05340658 chr4:99064831 C4orf37 0.64 11.65 0.53 1.25e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.18 0.55 1.39e-28 Height; LIHC cis rs919433 0.680 rs3792160 chr2:198403519 G/A cg10820045 chr2:198174542 NA 0.5 8.04 0.4 1.46e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs12594515 1.000 rs12906442 chr15:45985254 C/A cg06207120 chr15:45996521 NA 0.33 6.43 0.33 4.24e-10 Waist circumference;Weight; LIHC cis rs2303745 0.589 rs6512179 chr19:17399105 T/C cg02221750 chr19:17393354 ANKLE1 -0.41 -5.8 -0.3 1.53e-8 Systemic lupus erythematosus; LIHC cis rs2841277 0.712 rs2841280 chr14:105393556 G/C cg21017887 chr14:105400489 NA -0.67 -11.96 -0.54 9.07e-28 Rheumatoid arthritis; LIHC cis rs8141529 0.748 rs5752826 chr22:29269808 A/G cg02153584 chr22:29168773 CCDC117 0.53 8.31 0.41 2.33e-15 Lymphocyte counts; LIHC cis rs9457247 0.602 rs6456152 chr6:167472062 A/G cg07741184 chr6:167504864 NA 0.35 8.11 0.4 9.26e-15 Crohn's disease; LIHC cis rs2075371 0.829 rs1993058 chr7:133930361 G/A cg11752832 chr7:134001865 SLC35B4 0.49 6.25 0.32 1.24e-9 Mean platelet volume; LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg11965913 chr1:205819406 PM20D1 -0.58 -8.32 -0.41 2.08e-15 Menarche (age at onset); LIHC cis rs12477438 0.798 rs2084987 chr2:99587885 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.8 -11.81 -0.54 3.1e-27 Chronic sinus infection; LIHC cis rs2637266 0.729 rs1099883 chr10:78516158 G/T cg18941641 chr10:78392320 NA 0.27 5.84 0.3 1.22e-8 Pulmonary function; LIHC cis rs13108904 0.846 rs4974574 chr4:1224811 A/G cg13395646 chr4:1353034 KIAA1530 -0.55 -7.82 -0.39 6.48e-14 Obesity-related traits; LIHC cis rs12142240 0.731 rs6681857 chr1:46850124 T/C cg14993813 chr1:46806288 NSUN4 -0.65 -5.79 -0.3 1.62e-8 Menopause (age at onset); LIHC cis rs1005277 0.579 rs1780139 chr10:38503018 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.24 -0.32 1.3e-9 Extrinsic epigenetic age acceleration; LIHC trans rs2727020 0.615 rs4980435 chr11:49591576 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -22.4 -0.77 4.91e-69 Coronary artery disease; LIHC cis rs801193 0.935 rs2659916 chr7:66151352 C/G cg00343986 chr7:65444356 GUSB 0.39 5.85 0.3 1.14e-8 Aortic root size; LIHC cis rs9916302 0.800 rs11869259 chr17:37518141 C/A cg07936489 chr17:37558343 FBXL20 0.83 13.53 0.59 1.02e-33 Glomerular filtration rate (creatinine); LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg20360273 chr2:70056711 GMCL1 0.48 6.04 0.31 4.11e-9 Facial morphology (factor 20); LIHC cis rs2576037 0.526 rs9304340 chr18:44526582 G/A cg19077165 chr18:44547161 KATNAL2 -0.44 -6.65 -0.34 1.14e-10 Personality dimensions; LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg04025307 chr7:1156635 C7orf50 0.6 10.62 0.5 6.08e-23 Longevity;Endometriosis; LIHC cis rs12701220 0.522 rs12701455 chr7:1055409 A/G cg26769984 chr7:1090371 C7orf50 0.44 5.95 0.31 6.66e-9 Bronchopulmonary dysplasia; LIHC cis rs317689 0.819 rs317677 chr12:69691806 G/A cg20891283 chr12:69753455 YEATS4 0.57 8.62 0.42 2.56e-16 Response to diuretic therapy; LIHC cis rs898097 0.625 rs898095 chr17:80890638 T/C cg15664640 chr17:80829946 TBCD 0.43 7.26 0.37 2.61e-12 Breast cancer; LIHC cis rs12893668 0.542 rs12884809 chr14:104095320 G/A cg24130564 chr14:104152367 KLC1 -0.58 -9.94 -0.47 1.26e-20 Reticulocyte count; LIHC cis rs4728302 0.934 rs10258052 chr7:133635874 T/C cg10665199 chr7:133106180 EXOC4 -0.35 -5.86 -0.3 1.1e-8 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7727544 0.735 rs272867 chr5:131681057 G/A cg24060327 chr5:131705240 SLC22A5 -0.56 -8.08 -0.4 1.14e-14 Blood metabolite levels; LIHC cis rs9486715 1.000 rs11153085 chr6:97066355 A/T cg06623918 chr6:96969491 KIAA0776 -0.84 -13.77 -0.6 1.21e-34 Headache; LIHC cis rs8005677 1.000 rs7155857 chr14:23400059 C/A cg25600027 chr14:23388339 RBM23 -0.41 -5.91 -0.3 8.06e-9 Cognitive ability (multi-trait analysis); LIHC cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.55e-21 Intelligence (multi-trait analysis); LIHC cis rs60871478 0.947 rs62432255 chr7:804219 G/A cg04727924 chr7:799746 HEATR2 -0.58 -8.61 -0.42 2.7e-16 Cerebrospinal P-tau181p levels; LIHC cis rs2599510 0.811 rs176413 chr2:32646847 G/A cg02381751 chr2:32503542 YIPF4 -0.45 -6.22 -0.32 1.46e-9 Interleukin-18 levels; LIHC cis rs933688 0.526 rs7727632 chr5:90609009 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.49 -7.07 -0.36 8.83e-12 Smoking behavior; LIHC cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg24846343 chr22:24311635 DDTL 0.67 13.37 0.59 4.23e-33 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7095607 0.606 rs6480312 chr10:69957845 C/T cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.65e-9 Lung function (FVC); LIHC cis rs7582180 0.764 rs11686293 chr2:100922830 C/T cg14675211 chr2:100938903 LONRF2 0.51 8.05 0.4 1.36e-14 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs1647267 chr2:27651054 A/T cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs35110281 0.667 rs2838354 chr21:45119857 T/C cg04455712 chr21:45112962 RRP1B 0.46 8.0 0.4 1.94e-14 Mean corpuscular volume; LIHC cis rs7116495 1.000 rs116781589 chr11:71825006 G/T cg26138937 chr11:71823887 C11orf51 0.8 7.93 0.39 3.24e-14 Severe influenza A (H1N1) infection; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg14159672 chr1:205819179 PM20D1 0.69 9.72 0.47 7.18e-20 Menarche (age at onset); LIHC cis rs56146971 0.763 rs77450079 chr14:91863924 A/C cg16433844 chr14:91963127 SMEK1 -0.54 -6.34 -0.32 7.11e-10 Alzheimer disease and age of onset; LIHC cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.62 0.46 1.52e-19 Platelet count; LIHC trans rs216345 0.966 rs1971430 chr9:33782375 G/A cg14607208 chr9:38546089 NA 0.42 6.39 0.33 5.4e-10 Bipolar disorder; LIHC cis rs6835098 1.000 rs6835098 chr4:174089238 T/C cg08422745 chr4:174089978 GALNT7 -0.33 -5.86 -0.3 1.07e-8 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs3812831 0.643 rs7322339 chr13:114929726 C/A cg08824895 chr13:115047677 UPF3A 0.49 7.03 0.36 1.11e-11 Schizophrenia; LIHC cis rs6089829 0.888 rs4809468 chr20:61673566 T/C cg08564027 chr20:61660810 NA 0.37 6.74 0.34 6.94e-11 Prostate cancer (SNP x SNP interaction); LIHC cis rs9596863 1.000 rs9316669 chr13:54401836 C/G ch.13.53330881F chr13:54432880 NA 0.43 5.76 0.3 1.84e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs12497850 0.931 rs13315711 chr3:48986399 A/T cg06212747 chr3:49208901 KLHDC8B 0.56 7.19 0.36 4.06e-12 Parkinson's disease; LIHC cis rs1008375 1.000 rs1008374 chr4:17683219 G/A cg16339924 chr4:17578868 LAP3 0.4 5.88 0.3 9.51e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13445258 chr3:128369860 RPN1 0.48 7.15 0.36 5.26e-12 Pancreatic cancer; LIHC cis rs9372253 0.818 rs2207360 chr6:110706337 G/C cg00083206 chr6:110721305 DDO -0.33 -6.61 -0.34 1.44e-10 Platelet distribution width; LIHC cis rs17253792 0.822 rs74968702 chr14:56076818 A/T cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.37e-16 Putamen volume; LIHC cis rs10791097 0.694 rs4937581 chr11:130740335 T/C cg12179176 chr11:130786555 SNX19 0.81 13.05 0.58 7.15e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs875971 0.825 rs1860472 chr7:66082723 T/C cg11764359 chr7:65958608 NA -0.78 -13.64 -0.59 4.13e-34 Aortic root size; LIHC cis rs3806843 0.676 rs2245640 chr5:140029958 A/G cg16179182 chr5:140090404 VTRNA1-1 0.37 6.12 0.31 2.5e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1008375 0.932 rs4698627 chr4:17605959 T/C cg02297831 chr4:17616191 MED28 0.44 6.81 0.35 4.47e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs35110281 0.774 rs9978811 chr21:44998683 C/T cg04455712 chr21:45112962 RRP1B 0.46 7.96 0.4 2.63e-14 Mean corpuscular volume; LIHC cis rs17106184 1.000 rs72896994 chr1:50891117 C/A cg07174182 chr1:51127561 FAF1 -0.57 -6.26 -0.32 1.16e-9 Type 2 diabetes; LIHC cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg11905131 chr22:24372483 LOC391322 0.7 10.99 0.51 2.92e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs700651 0.789 rs5007118 chr2:198909738 G/C cg03934865 chr2:198174659 NA 0.46 6.48 0.33 3.28e-10 Intracranial aneurysm; LIHC cis rs9486715 0.830 rs4425602 chr6:96893906 G/A cg06623918 chr6:96969491 KIAA0776 0.83 14.59 0.62 8.16e-38 Headache; LIHC cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg07092213 chr7:1199455 ZFAND2A -0.43 -6.3 -0.32 8.9e-10 Longevity;Endometriosis; LIHC cis rs7659604 0.539 rs11098648 chr4:122759872 C/T cg19748678 chr4:122722346 EXOSC9 0.68 11.31 0.52 2.15e-25 Type 2 diabetes; LIHC cis rs6545883 0.894 rs2694632 chr2:61558682 T/C cg14146966 chr2:61757674 XPO1 -0.44 -7.44 -0.37 7.95e-13 Tuberculosis; LIHC cis rs7116495 1.000 rs73539532 chr11:71815684 C/A cg26138937 chr11:71823887 C11orf51 0.82 8.15 0.4 7.04e-15 Severe influenza A (H1N1) infection; LIHC cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg15782153 chr7:917662 C7orf20 0.41 6.77 0.34 5.75e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs7618501 0.573 rs7634917 chr3:50049299 T/G cg24110177 chr3:50126178 RBM5 0.49 7.84 0.39 5.75e-14 Intelligence (multi-trait analysis); LIHC cis rs7927771 0.832 rs1317164 chr11:47419757 G/T cg20307385 chr11:47447363 PSMC3 -0.46 -6.1 -0.31 2.85e-9 Subjective well-being; LIHC cis rs67311347 1.000 rs28434528 chr3:40484893 A/G cg24209194 chr3:40518798 ZNF619 0.49 7.37 0.37 1.32e-12 Renal cell carcinoma; LIHC cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12478296 0.685 rs35577962 chr2:242993575 A/G cg18898632 chr2:242989856 NA -0.51 -7.07 -0.36 8.53e-12 Obesity-related traits; LIHC cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.68 6.52 0.33 2.56e-10 Lung function (FEV1/FVC); LIHC trans rs35110281 0.622 rs9977258 chr21:44976485 G/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.49 6.66 0.34 1.1e-10 Mean corpuscular volume; LIHC cis rs1008375 0.863 rs4590022 chr4:17614434 T/C cg16339924 chr4:17578868 LAP3 0.42 5.83 0.3 1.27e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg03395511 chr6:291903 DUSP22 -0.52 -7.24 -0.36 2.9e-12 Menopause (age at onset); LIHC cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg03721293 chr16:90014378 DEF8 0.39 6.62 0.34 1.38e-10 Skin colour saturation; LIHC cis rs6089584 0.819 rs1467593 chr20:60601432 T/G cg13770153 chr20:60521292 NA 0.38 7.24 0.36 2.92e-12 Body mass index; LIHC cis rs10464366 0.614 rs62442213 chr7:39146933 C/T cg15212455 chr7:39170539 POU6F2 0.47 8.33 0.41 1.93e-15 IgG glycosylation; LIHC cis rs1461503 0.932 rs11218909 chr11:122842613 C/T cg14473756 chr11:122847823 NA -0.37 -6.71 -0.34 8.29e-11 Menarche (age at onset); LIHC cis rs244293 0.965 rs244340 chr17:53199345 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.5 -0.38 5.39e-13 Menarche (age at onset); LIHC cis rs507080 0.961 rs642530 chr11:118550756 A/G cg04173919 chr11:118528438 PHLDB1 0.32 6.07 0.31 3.43e-9 Serum metabolite levels; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg03395511 chr6:291903 DUSP22 -0.5 -6.82 -0.35 4.08e-11 Menopause (age at onset); LIHC cis rs9388451 0.839 rs4897155 chr6:126095144 C/A cg05901451 chr6:126070800 HEY2 -0.76 -17.64 -0.69 5.3e-50 Brugada syndrome; LIHC cis rs11098499 0.909 rs10002083 chr4:120311152 C/T cg09307838 chr4:120376055 NA 0.76 11.69 0.53 8.92e-27 Corneal astigmatism; LIHC cis rs13272623 0.502 rs268628 chr8:71560505 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.45 -5.9 -0.3 8.95e-9 IgG glycosylation; LIHC cis rs244293 0.965 rs2529506 chr17:53211177 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.49 -7.3 -0.37 2.04e-12 Menarche (age at onset); LIHC cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg24549020 chr5:56110836 MAP3K1 0.5 6.49 0.33 3.01e-10 Initial pursuit acceleration; LIHC cis rs3888647 0.622 rs4758618 chr11:2995186 A/T cg25174290 chr11:3078921 CARS 0.57 8.71 0.43 1.28e-16 Type 2 diabetes; LIHC cis rs6754311 0.509 rs10188066 chr2:136539513 G/A cg07169764 chr2:136633963 MCM6 -0.78 -11.71 -0.53 7.57e-27 Mosquito bite size; LIHC cis rs4975616 0.804 rs381949 chr5:1322468 G/A cg07493874 chr5:1342172 CLPTM1L -0.67 -10.77 -0.5 1.81e-23 Lung cancer; LIHC cis rs4906332 0.966 rs17679729 chr14:103924312 A/G cg19000871 chr14:103996768 TRMT61A -0.46 -7.72 -0.39 1.26e-13 Coronary artery disease; LIHC trans rs62103177 0.810 rs3902996 chr18:77630571 A/G cg05926928 chr17:57297772 GDPD1 1.1 11.26 0.52 3.23e-25 Opioid sensitivity; LIHC cis rs11758351 0.587 rs16891466 chr6:26235737 G/A cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.05e-12 Gout;Renal underexcretion gout; LIHC cis rs12478296 0.901 rs58906257 chr2:243028248 T/C cg06360820 chr2:242988706 NA -0.79 -11.46 -0.53 5.92e-26 Obesity-related traits; LIHC cis rs17376456 0.825 rs6865441 chr5:93284746 G/A cg25358565 chr5:93447407 FAM172A 1.09 9.82 0.47 3.33e-20 Diabetic retinopathy; LIHC cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg06453172 chr10:134556979 INPP5A 0.64 8.42 0.41 1.02e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs79149102 0.579 rs58645417 chr15:75325858 T/G cg09165964 chr15:75287851 SCAMP5 -0.61 -8.21 -0.41 4.49e-15 Lung cancer; LIHC cis rs6076065 0.707 rs2424555 chr20:23417705 A/G cg11657817 chr20:23433608 CST11 0.31 6.71 0.34 8.07e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs1506636 1.000 rs2429619 chr7:123425599 C/G cg03229431 chr7:123269106 ASB15 0.6 11.91 0.54 1.36e-27 Plateletcrit;Platelet count; LIHC cis rs3784262 1.000 rs7178497 chr15:58240333 C/T cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.08 -0.31 3.18e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg26367235 chr2:239997305 HDAC4 0.45 6.09 0.31 3.01e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg22633049 chr21:46681294 NA -0.37 -6.31 -0.32 8.75e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5769765 0.955 rs8135963 chr22:50301476 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -9.24 -0.45 2.71e-18 Schizophrenia; LIHC cis rs11098499 0.697 rs11941899 chr4:120382758 C/A cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs7208859 0.623 rs9911784 chr17:29124580 A/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08556938 chr17:58512855 NA -0.45 -7.19 -0.36 4.21e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs1198430 0.639 rs1767147 chr1:23770516 A/G cg13183780 chr1:23809682 ASAP3 -0.38 -6.54 -0.33 2.21e-10 Total cholesterol levels; LIHC cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg10802521 chr3:52805072 NEK4 -0.43 -7.08 -0.36 8.14e-12 Bipolar disorder; LIHC cis rs2758596 0.850 rs2241110 chr1:156172487 A/G cg25208724 chr1:156163844 SLC25A44 0.75 9.16 0.44 5.03e-18 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.89 -0.3 9.27e-9 Total body bone mineral density; LIHC cis rs8078723 0.714 rs2241245 chr17:38151014 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.65 11.35 0.52 1.44e-25 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7914558 1.000 rs11191539 chr10:104819770 A/G cg15744005 chr10:104629667 AS3MT -0.39 -8.86 -0.43 4.32e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs1461503 0.934 rs7115651 chr11:122831882 C/T cg25161029 chr11:122845972 NA 0.41 6.7 0.34 8.41e-11 Menarche (age at onset); LIHC cis rs3096299 0.900 rs744327 chr16:89439270 C/T cg06640241 chr16:89574553 SPG7 0.63 9.96 0.47 1.12e-20 Multiple myeloma (IgH translocation); LIHC cis rs35110281 0.744 rs8131027 chr21:45104908 G/C cg04455712 chr21:45112962 RRP1B 0.49 8.65 0.42 2.07e-16 Mean corpuscular volume; LIHC cis rs6450176 1.000 rs3776703 chr5:53305259 T/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.66 -0.62 4.37e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2933343 0.700 rs789240 chr3:128630635 T/C cg24203234 chr3:128598194 ACAD9 0.45 6.29 0.32 9.77e-10 IgG glycosylation; LIHC cis rs3096299 0.685 rs2911244 chr16:89521860 A/G cg02034447 chr16:89574710 SPG7 0.48 7.43 0.37 8.71e-13 Multiple myeloma (IgH translocation); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg22174410 chr3:42641766 NKTR 0.45 6.82 0.35 4.07e-11 Cognitive function; LIHC cis rs919433 0.927 rs3843857 chr2:198195965 T/C cg03934865 chr2:198174659 NA -0.55 -8.65 -0.42 2.1e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs60871478 1.000 rs62432861 chr7:807649 G/A cg05535760 chr7:792225 HEATR2 0.8 11.29 0.52 2.46e-25 Cerebrospinal P-tau181p levels; LIHC cis rs11758351 0.715 rs75390741 chr6:26209784 A/T cg03854865 chr6:26224070 HIST1H3E 0.59 6.43 0.33 4.36e-10 Gout;Renal underexcretion gout; LIHC cis rs2153535 0.580 rs6921036 chr6:8455400 G/A cg07606381 chr6:8435919 SLC35B3 0.8 11.9 0.54 1.44e-27 Motion sickness; LIHC cis rs2455799 0.613 rs3924773 chr3:15796853 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg12516959 chr21:47718080 NA 0.36 5.85 0.3 1.17e-8 Testicular germ cell tumor; LIHC trans rs7615952 0.688 rs9754526 chr3:125542866 C/A cg07211511 chr3:129823064 LOC729375 -0.49 -7.65 -0.38 2.11e-13 Blood pressure (smoking interaction); LIHC cis rs1801251 0.711 rs2592117 chr2:233735693 C/T cg25237894 chr2:233734115 C2orf82 -0.59 -11.92 -0.54 1.29e-27 Coronary artery disease; LIHC cis rs8084351 0.577 rs55808525 chr18:50612317 G/A cg24270629 chr18:50823537 DCC 0.43 6.36 0.33 6.63e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC trans rs208515 0.525 rs10944870 chr6:66687757 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 8.86 0.43 4.37e-17 Exhaled nitric oxide levels; LIHC cis rs611744 0.658 rs2443775 chr8:109062481 A/G cg21045802 chr8:109455806 TTC35 -0.42 -7.14 -0.36 5.75e-12 Dupuytren's disease; LIHC cis rs17376456 0.877 rs34673483 chr5:93315079 C/A cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg00091569 chr3:40428383 ENTPD3 0.39 6.75 0.34 6.28e-11 Renal cell carcinoma; LIHC cis rs2421770 0.530 rs2421764 chr11:35364578 A/T cg13971030 chr11:35366721 SLC1A2 -0.45 -7.59 -0.38 3.02e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs9457247 1.000 rs386548 chr6:167385533 A/T cg23791538 chr6:167370224 RNASET2 0.66 11.41 0.53 8.67e-26 Crohn's disease; LIHC cis rs937213 0.573 rs3816900 chr15:40302243 C/T cg16127683 chr15:40268777 EIF2AK4 -0.36 -5.89 -0.3 9.23e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs5758511 0.514 rs5751240 chr22:42595258 G/C cg00645731 chr22:42541494 CYP2D7P1 0.53 8.43 0.41 1e-15 Birth weight; LIHC cis rs826838 1.000 rs11169031 chr12:39056738 T/C cg26384229 chr12:38710491 ALG10B 0.87 11.49 0.53 4.51e-26 Heart rate; LIHC cis rs796364 1.000 rs281774 chr2:200814572 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 8.28 0.41 2.85e-15 Schizophrenia; LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg01411255 chr17:61851458 DDX42;CCDC47 -0.93 -19.31 -0.72 1.05e-56 Height; LIHC cis rs7192750 0.562 rs152838 chr16:72105702 C/T cg14768367 chr16:72042858 DHODH 0.65 6.16 0.32 2.04e-9 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs17253792 0.822 rs45501402 chr14:56140115 C/T cg01858014 chr14:56050164 KTN1 -0.7 -7.28 -0.37 2.32e-12 Putamen volume; LIHC cis rs61677309 1.000 rs1318166 chr11:118171058 A/G cg06090739 chr11:118230722 UBE4A 0.36 6.68 0.34 9.52e-11 Lung cancer in ever smokers; LIHC cis rs2806561 0.704 rs588387 chr1:23523689 A/G cg11953164 chr1:23521307 HTR1D 0.29 5.74 0.3 2.05e-8 Height; LIHC cis rs11122272 0.735 rs971534 chr1:231521971 C/A cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs7927592 0.763 rs3740628 chr11:68381415 A/G cg01657329 chr11:68192670 LRP5 -0.5 -7.38 -0.37 1.21e-12 Total body bone mineral density; LIHC cis rs6089584 1.000 rs6142910 chr20:60562181 C/A cg06108461 chr20:60628389 TAF4 -0.88 -13.71 -0.6 2.16e-34 Body mass index; LIHC cis rs7107174 1.000 rs11237460 chr11:78056274 G/A cg02023728 chr11:77925099 USP35 0.41 7.77 0.39 9.21e-14 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs7341206 chr6:8470489 T/G cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs6500602 0.702 rs2304634 chr16:4500544 C/T cg08645402 chr16:4508243 NA 0.46 9.13 0.44 5.9e-18 Schizophrenia; LIHC cis rs17384381 0.953 rs12130145 chr1:85828970 G/C cg16011679 chr1:85725395 C1orf52 0.85 8.79 0.43 7.29e-17 Lobe attachment (rater-scored or self-reported); LIHC trans rs11088226 0.692 rs28709516 chr21:33890366 G/A cg09050820 chr6:167586206 TCP10L2 0.44 6.49 0.33 3.03e-10 Gastritis; LIHC cis rs1008375 0.932 rs13134570 chr4:17692863 C/T cg16339924 chr4:17578868 LAP3 -0.45 -5.86 -0.3 1.09e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2842992 0.747 rs733319 chr6:160221475 A/G cg11366901 chr6:160182831 ACAT2 0.96 15.98 0.65 2.63e-43 Age-related macular degeneration (geographic atrophy); LIHC trans rs6489882 0.671 rs4767027 chr12:113359157 T/C cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs1555399 0.901 rs7140327 chr14:67983540 T/G cg16224230 chr14:67978224 TMEM229B -0.24 -5.91 -0.3 8.43e-9 Parkinson's disease; LIHC cis rs921968 0.678 rs2230115 chr2:219509618 C/A cg18887096 chr2:219472410 PLCD4 0.39 6.69 0.34 9.34e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs13098911 0.540 rs34381952 chr3:45995748 T/C cg21656520 chr2:210867290 RPE 0.85 6.08 0.31 3.19e-9 Celiac disease; LIHC cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.54 -0.38 4.25e-13 Bipolar disorder; LIHC cis rs9902453 0.872 rs34698290 chr17:28500465 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.4 0.45 7.96e-19 Coffee consumption (cups per day); LIHC cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg07061783 chr6:25882402 NA -0.48 -6.65 -0.34 1.13e-10 Blood metabolite levels; LIHC cis rs763014 0.932 rs35067229 chr16:649638 T/C cg07343612 chr16:622815 PIGQ -0.85 -15.78 -0.65 1.62e-42 Height; LIHC cis rs11212260 0.655 rs77889759 chr11:107285328 A/G cg25435332 chr11:107328525 CWF19L2 0.8 8.45 0.42 8.24e-16 IgG glycosylation; LIHC cis rs727505 0.909 rs1031957 chr7:124627301 T/C cg23710748 chr7:124431027 NA -0.33 -5.92 -0.3 7.96e-9 Lewy body disease; LIHC cis rs7412746 0.658 rs4970988 chr1:150950062 A/G cg15448220 chr1:150897856 SETDB1 -0.43 -6.88 -0.35 2.88e-11 Melanoma; LIHC cis rs870825 0.860 rs72703519 chr4:185602707 G/A cg04058563 chr4:185651563 MLF1IP 0.76 6.49 0.33 3.05e-10 Blood protein levels; LIHC cis rs1355223 0.902 rs1453380 chr11:34703682 C/G cg11058730 chr11:34937778 PDHX;APIP -0.42 -5.8 -0.3 1.51e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11112613 0.713 rs11112592 chr12:105951702 C/T cg03607813 chr12:105948248 NA -0.63 -12.28 -0.55 5.54e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11449408 chr17:80856057 TBCD 0.51 6.3 0.32 8.97e-10 Systolic blood pressure; LIHC cis rs1789 0.872 rs4333182 chr4:15684712 G/A cg21123203 chr4:15471301 CC2D2A -0.43 -6.53 -0.33 2.32e-10 Blood protein levels; LIHC cis rs9733 0.566 rs72702554 chr1:150678234 A/G cg17724175 chr1:150552817 MCL1 0.48 9.74 0.47 6.17e-20 Tonsillectomy; LIHC cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg24642844 chr7:1081250 C7orf50 -0.91 -8.95 -0.44 2.36e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7520050 0.966 rs11211230 chr1:46406767 G/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.13 0.31 2.39e-9 Red blood cell count;Reticulocyte count; LIHC cis rs12908161 0.959 rs2175567 chr15:85200946 C/G cg12863693 chr15:85201151 NMB 0.48 6.75 0.34 6.2e-11 Schizophrenia; LIHC cis rs11212260 0.655 rs11212239 chr11:107312175 G/A cg25435332 chr11:107328525 CWF19L2 0.82 8.3 0.41 2.4e-15 IgG glycosylation; LIHC cis rs16828019 0.929 rs8179465 chr1:41701747 C/T cg20697417 chr1:41786797 NA 0.33 6.38 0.33 5.74e-10 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.718 rs1960421 chr9:123394894 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.0 0.51 2.62e-24 Hip circumference adjusted for BMI; LIHC cis rs5769707 0.732 rs135865 chr22:50004829 G/A cg01652190 chr22:50026171 C22orf34 -0.32 -7.47 -0.37 6.59e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs10489202 1.000 rs17557135 chr1:167985888 A/G cg24449463 chr1:168025552 DCAF6 -0.51 -6.4 -0.33 5.12e-10 Schizophrenia; LIHC cis rs1215050 0.791 rs260899 chr4:98707046 G/A cg05340658 chr4:99064831 C4orf37 0.39 5.78 0.3 1.71e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs1932284 chr6:8477694 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.64 0.42 2.24e-16 Motion sickness; LIHC cis rs17152411 0.652 rs1036676 chr10:126654184 A/G cg07906193 chr10:126599966 NA -0.3 -6.05 -0.31 3.89e-9 Height; LIHC cis rs11958404 0.932 rs12514557 chr5:157418954 T/C cg05962755 chr5:157440814 NA 0.96 10.52 0.49 1.28e-22 IgG glycosylation; LIHC cis rs7552404 1.000 rs1498312 chr1:76177849 C/T cg03433033 chr1:76189801 ACADM 0.67 9.44 0.45 5.9e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs12142240 0.698 rs10158130 chr1:46822600 T/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs1568889 1.000 rs58502944 chr11:28060943 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.45 5.93 0.31 7.26e-9 Bipolar disorder; LIHC cis rs1552244 0.572 rs17032426 chr3:10167112 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs13118159 0.651 rs4974599 chr4:1314430 A/C cg13395646 chr4:1353034 KIAA1530 -0.43 -6.34 -0.32 7.16e-10 Longevity; LIHC cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg00166722 chr3:10149974 C3orf24 0.48 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC cis rs3806843 0.676 rs778594 chr5:140027304 T/C cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.63e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs7618501 0.633 rs4688755 chr3:50064424 G/A cg21659725 chr3:3221576 CRBN -0.69 -11.26 -0.52 3.22e-25 Intelligence (multi-trait analysis); LIHC cis rs6424115 0.830 rs2502999 chr1:24198321 A/G cg10978503 chr1:24200527 CNR2 0.34 8.25 0.41 3.46e-15 Immature fraction of reticulocytes; LIHC cis rs7927592 0.956 rs7106259 chr11:68298512 T/G cg16797656 chr11:68205561 LRP5 0.52 8.2 0.41 5.07e-15 Total body bone mineral density; LIHC cis rs3770081 0.793 rs75675321 chr2:86238994 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.82 -8.42 -0.41 1.03e-15 Facial emotion recognition (sad faces); LIHC cis rs6964587 0.934 rs12531561 chr7:91707780 A/G cg17063962 chr7:91808500 NA 1.0 19.0 0.72 1.78e-55 Breast cancer; LIHC cis rs2832191 0.550 rs66484040 chr21:30511691 G/A cg08807101 chr21:30365312 RNF160 -0.42 -6.1 -0.31 2.94e-9 Dental caries; LIHC cis rs477895 1.000 rs7938380 chr11:64034866 G/A cg04317338 chr11:64019027 PLCB3 0.84 8.41 0.41 1.14e-15 Mean platelet volume; LIHC cis rs2404602 0.692 rs1867197 chr15:76910031 A/G cg03037974 chr15:76606532 NA -0.65 -12.33 -0.55 3.7e-29 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20610891 chr12:52463737 C12orf44 0.43 6.1 0.31 2.88e-9 Lung function (FEV1/FVC); LIHC cis rs2658782 0.547 rs10765602 chr11:93048165 G/T cg15737290 chr11:93063684 CCDC67 0.45 6.02 0.31 4.58e-9 Pulmonary function decline; LIHC cis rs1215050 0.755 rs7696354 chr4:98820330 T/C cg05340658 chr4:99064831 C4orf37 0.39 5.82 0.3 1.32e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11702148 0.552 rs9977929 chr21:34873716 C/G cg14850771 chr21:34775459 IFNGR2 0.47 7.65 0.38 2.06e-13 Mean corpuscular hemoglobin; LIHC cis rs6963495 0.818 rs55740553 chr7:105159551 A/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC trans rs11098499 0.863 rs3775845 chr4:120432447 T/C cg25214090 chr10:38739885 LOC399744 0.59 9.55 0.46 2.59e-19 Corneal astigmatism; LIHC trans rs7613875 0.620 rs3774734 chr3:50108792 C/A cg21659725 chr3:3221576 CRBN -0.54 -8.06 -0.4 1.25e-14 Body mass index; LIHC cis rs66569888 0.581 rs17271098 chr2:106692818 A/G cg15412446 chr2:106886593 NA 0.56 5.74 0.3 2.05e-8 Facial morphology (factor 23); LIHC cis rs3770081 1.000 rs58515922 chr2:86173037 A/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.73 -7.91 -0.39 3.72e-14 Facial emotion recognition (sad faces); LIHC cis rs875971 0.825 rs1000464 chr7:65777909 G/C cg18876405 chr7:65276391 NA -0.35 -6.31 -0.32 8.41e-10 Aortic root size; LIHC cis rs7107174 0.892 rs10899482 chr11:78060081 A/C cg02023728 chr11:77925099 USP35 0.43 8.37 0.41 1.53e-15 Testicular germ cell tumor; LIHC cis rs7584330 0.554 rs10173100 chr2:238433040 A/G cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.39e-9 Prostate cancer; LIHC cis rs7903847 0.642 rs11189172 chr10:99135215 T/C cg08345082 chr10:99160200 RRP12 -0.36 -6.01 -0.31 4.74e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs4908768 0.906 rs55858268 chr1:8554696 C/T cg20416874 chr1:8611966 RERE 0.57 8.8 0.43 6.93e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs11588062 0.703 rs11589812 chr1:46858748 C/T cg06787764 chr1:46668870 C1orf190;POMGNT1 0.49 7.42 0.37 9.37e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3008870 0.755 rs2815355 chr1:67485034 A/G cg02640540 chr1:67518911 SLC35D1 0.44 6.85 0.35 3.47e-11 Lymphocyte percentage of white cells; LIHC cis rs2637266 1.000 rs10824431 chr10:78356622 C/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg00684032 chr4:1343700 KIAA1530 0.52 7.54 0.38 4.36e-13 Obesity-related traits; LIHC cis rs10870270 1.000 rs10430617 chr10:133748889 T/C cg08754478 chr10:133766260 PPP2R2D -0.53 -7.75 -0.39 1.07e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs11148252 0.875 rs4885953 chr13:52976491 G/A cg00495681 chr13:53174319 NA 0.38 6.18 0.32 1.82e-9 Lewy body disease; LIHC cis rs4865169 0.934 rs3796531 chr4:57850846 A/G cg25525207 chr4:57843836 C4orf14;POLR2B 0.37 5.8 0.3 1.5e-8 Breast cancer; LIHC cis rs2257205 0.667 rs16943186 chr17:56801848 C/T cg12560992 chr17:57184187 TRIM37 0.72 7.9 0.39 3.98e-14 Pancreatic cancer; LIHC cis rs2074585 0.647 rs2601188 chr15:90929563 A/G cg22089800 chr15:90895588 ZNF774 -0.61 -8.6 -0.42 2.96e-16 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs3617 0.625 rs7617468 chr3:52849549 T/C cg11645453 chr3:52864694 ITIH4 0.22 6.12 0.31 2.56e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg18252515 chr7:66147081 NA 1.27 16.64 0.67 5.64e-46 Diabetic kidney disease; LIHC cis rs12744310 0.887 rs16828067 chr1:41783552 A/G cg03962019 chr1:41807865 NA 0.4 6.37 0.33 6.06e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs61990749 0.597 rs4903643 chr14:78254791 C/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.64 -0.38 2.22e-13 Fibroblast growth factor basic levels; LIHC cis rs2370759 1.000 rs76998371 chr10:32631785 A/G cg05361325 chr10:32636312 EPC1 -0.52 -6.36 -0.33 6.3e-10 Sexual dysfunction (female); LIHC cis rs4654899 0.965 rs2873424 chr1:21500701 C/A cg08539965 chr1:21396338 EIF4G3 0.32 5.73 0.3 2.26e-8 Superior frontal gyrus grey matter volume; LIHC cis rs9549328 0.800 rs9549617 chr13:113628070 C/A cg08528486 chr13:113648767 MCF2L -0.42 -6.64 -0.34 1.27e-10 Systolic blood pressure; LIHC cis rs2274273 0.870 rs10147434 chr14:55674847 C/T cg01864836 chr14:55583639 NA -0.41 -7.84 -0.39 5.63e-14 Protein biomarker; LIHC cis rs3762637 1.000 rs12638866 chr3:122194382 T/C cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs4788570 0.584 rs6499529 chr16:71715378 C/T cg06353428 chr16:71660113 MARVELD3 1.39 14.48 0.62 2.14e-37 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg21747090 chr2:27597821 SNX17 -0.42 -6.32 -0.32 8.03e-10 Total body bone mineral density; LIHC cis rs782590 0.967 rs1084522 chr2:55843294 A/G cg03859395 chr2:55845619 SMEK2 0.93 16.66 0.67 4.63e-46 Metabolic syndrome; LIHC trans rs7618501 0.602 rs2624816 chr3:50117312 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.55 -8.85 -0.43 4.86e-17 Intelligence (multi-trait analysis); LIHC cis rs16974263 1.000 rs16974263 chr19:40913539 A/G cg14150973 chr19:40950431 SERTAD3 -0.68 -7.28 -0.37 2.25e-12 Otitis media;Otitis media (chronic);Otitis media (recurrent); LIHC cis rs2153535 0.542 rs4440510 chr6:8471818 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7474896 0.515 rs2749582 chr10:38275284 A/G cg25427524 chr10:38739819 LOC399744 0.44 5.86 0.3 1.07e-8 Obesity (extreme); LIHC cis rs317689 0.690 rs317656 chr12:69681101 T/A cg19645103 chr12:69753606 YEATS4 -0.46 -6.1 -0.31 2.8e-9 Response to diuretic therapy; LIHC trans rs7395555 1.000 rs11232095 chr11:80062406 A/C cg06295071 chr21:33766731 URB1 0.45 6.3 0.32 9.23e-10 Response to antipsychotic treatment; LIHC cis rs875971 0.862 rs778686 chr7:65835910 C/T cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs17384381 0.700 rs11161617 chr1:85913538 A/G cg16011679 chr1:85725395 C1orf52 0.56 6.74 0.34 6.71e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.862 rs4718330 chr7:65715243 G/A cg18252515 chr7:66147081 NA 0.42 5.89 0.3 9.4e-9 Aortic root size; LIHC cis rs1728785 1.000 rs1645935 chr16:68563791 A/C cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs72781680 0.898 rs72796158 chr2:23935727 T/C cg08917208 chr2:24149416 ATAD2B 0.96 8.22 0.41 4.3e-15 Lymphocyte counts; LIHC cis rs9399135 0.967 rs9376082 chr6:135346389 T/A cg22676075 chr6:135203613 NA 0.39 6.29 0.32 9.77e-10 Red blood cell count; LIHC cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg05665937 chr4:1216051 CTBP1 0.45 5.98 0.31 5.51e-9 Obesity-related traits; LIHC cis rs6952808 0.531 rs3778991 chr7:2172455 G/A cg04267008 chr7:1944627 MAD1L1 -0.5 -7.77 -0.39 9.47e-14 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg20607798 chr8:58055168 NA 0.73 8.6 0.42 2.99e-16 Developmental language disorder (linguistic errors); LIHC cis rs7106204 0.748 rs7101572 chr11:24213982 A/G ch.11.24196551F chr11:24239977 NA 0.76 10.16 0.48 2.29e-21 Response to Homoharringtonine (cytotoxicity); LIHC trans rs3780486 0.846 rs7873903 chr9:33142728 G/A cg20290983 chr6:43655470 MRPS18A 1.18 30.61 0.86 5.36e-100 IgG glycosylation; LIHC cis rs10779751 0.734 rs1130683 chr1:11132217 G/A cg08854313 chr1:11322531 MTOR 0.66 10.07 0.48 4.8e-21 Body mass index; LIHC cis rs12711979 0.509 rs10191674 chr2:3827891 C/T cg17052675 chr2:3827356 NA -0.7 -15.87 -0.65 6.77e-43 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs904251 1.000 rs10947673 chr6:37445079 C/T cg01843034 chr6:37503916 NA -0.35 -5.8 -0.3 1.48e-8 Cognitive performance; LIHC cis rs17711722 0.583 rs10085415 chr7:65093568 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.32 -0.32 8.35e-10 Calcium levels; LIHC cis rs7520050 0.966 rs61102033 chr1:46382441 G/T cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs8108269 1.000 rs10403962 chr19:46160638 C/A cg13320842 chr19:46175254 GIPR 0.43 8.04 0.4 1.48e-14 Type 2 diabetes; LIHC cis rs2857078 0.654 rs9896789 chr17:42314567 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.37 6.62 0.34 1.38e-10 Red cell distribution width;Reticulocyte count; LIHC cis rs9818758 0.556 rs9835439 chr3:49220330 G/C cg00383909 chr3:49044727 WDR6 0.79 6.56 0.33 2.02e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs8078723 0.668 rs3859192 chr17:38128648 C/T cg17344932 chr17:38183730 MED24;SNORD124 -0.53 -8.68 -0.42 1.66e-16 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs1816752 0.819 rs6490917 chr13:24997257 G/T cg22771759 chr13:24902376 NA 0.29 5.89 0.3 9.29e-9 Obesity-related traits; LIHC cis rs739401 0.572 rs410820 chr11:3080102 G/A cg05729581 chr11:3078854 CARS -0.45 -6.11 -0.31 2.67e-9 Longevity; LIHC cis rs911555 0.511 rs2296483 chr14:104029792 G/A cg11828104 chr14:104152337 KLC1 0.38 5.75 0.3 1.97e-8 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg18404041 chr3:52824283 ITIH1 -0.58 -9.62 -0.46 1.47e-19 Bipolar disorder; LIHC cis rs8067545 0.750 rs4925069 chr17:19953531 C/G cg13482628 chr17:19912719 NA 0.48 8.0 0.4 1.97e-14 Schizophrenia; LIHC cis rs5769765 0.773 rs9616208 chr22:50313359 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.33 -0.49 5.74e-22 Schizophrenia; LIHC cis rs10197940 0.578 rs1061305 chr2:152346979 T/C cg06191203 chr2:152266755 RIF1 -0.41 -7.16 -0.36 5.06e-12 Lung cancer; LIHC cis rs4629710 0.592 rs749375 chr6:131553692 C/G cg12606694 chr6:131520996 AKAP7 0.64 7.39 0.37 1.13e-12 Multiple myeloma (IgH translocation); LIHC trans rs61931739 0.500 rs56056630 chr12:34543465 T/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg00280220 chr17:61926910 NA 0.42 6.74 0.34 6.67e-11 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19853194 chr18:9913725 VAPA 0.43 7.62 0.38 2.55e-13 Cognitive function; LIHC cis rs929354 0.772 rs6971896 chr7:156978412 C/T cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs7647973 0.626 rs2131108 chr3:49665390 C/T cg03060546 chr3:49711283 APEH 0.59 6.77 0.34 5.61e-11 Menarche (age at onset); LIHC cis rs13108904 0.557 rs1250097 chr4:1238338 C/T cg16405210 chr4:1374714 KIAA1530 0.7 10.44 0.49 2.57e-22 Obesity-related traits; LIHC trans rs8002861 0.935 rs7318147 chr13:44445153 C/G cg11294084 chr13:33002136 N4BP2L1 0.45 6.05 0.31 3.84e-9 Leprosy; LIHC cis rs17253792 0.822 rs8007065 chr14:56081272 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs10905065 0.862 rs9423948 chr10:5742491 G/A cg11519256 chr10:5708881 ASB13 0.46 6.11 0.31 2.79e-9 Menopause (age at onset); LIHC trans rs17685 0.671 rs60303271 chr7:75760008 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4407350 0.837 rs4823326 chr22:44908678 C/T cg26276947 chr22:44892394 LDOC1L 0.35 6.76 0.34 5.92e-11 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.702 rs62052710 chr16:89854893 C/T cg00800038 chr16:89945340 TCF25 -0.59 -8.21 -0.41 4.6e-15 Skin colour saturation; LIHC cis rs67478160 0.619 rs55824307 chr14:104271207 C/T cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs72781680 0.848 rs2339926 chr2:24045734 C/G cg08917208 chr2:24149416 ATAD2B 0.87 8.23 0.41 3.95e-15 Lymphocyte counts; LIHC cis rs2404602 0.698 rs12909656 chr15:76664378 A/T cg23625390 chr15:77176239 SCAPER -0.48 -8.0 -0.4 1.99e-14 Blood metabolite levels; LIHC cis rs5997397 0.967 rs5752791 chr22:29153547 A/G cg15103426 chr22:29168792 CCDC117 -0.55 -8.83 -0.43 5.65e-17 Red cell distribution width; LIHC cis rs1348850 0.526 rs10930797 chr2:178437553 C/G cg27490568 chr2:178487706 NA 1.06 12.04 0.55 4.5e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs3903072 0.652 rs501630 chr11:65637273 A/G cg26695010 chr11:65641043 EFEMP2 0.5 6.81 0.35 4.49e-11 Breast cancer; LIHC cis rs5769765 0.779 rs12170530 chr22:50318422 T/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.75 -9.41 -0.45 7.59e-19 Schizophrenia; LIHC cis rs611744 0.967 rs2600615 chr8:109201170 G/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs7726839 0.540 rs11739847 chr5:609661 G/A cg09021430 chr5:549028 NA -0.43 -8.58 -0.42 3.34e-16 Obesity-related traits; LIHC cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg14004847 chr7:1930337 MAD1L1 -0.44 -6.4 -0.33 5.22e-10 Bipolar disorder and schizophrenia; LIHC cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.44e-8 Alzheimer's disease; LIHC cis rs7312933 0.558 rs11181502 chr12:42823833 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.87 0.39 4.64e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs1437396 0.609 rs11125567 chr2:55627913 C/T cg17631914 chr4:49514820 NA -0.31 -6.04 -0.31 3.95e-9 Alcohol dependence; LIHC cis rs8180040 0.800 rs2088135 chr3:47280018 T/C cg27129171 chr3:47204927 SETD2 -0.56 -9.11 -0.44 6.87e-18 Colorectal cancer; LIHC cis rs2070433 0.539 rs2839312 chr21:47958225 T/C cg12379764 chr21:47803548 PCNT 0.64 9.9 0.47 1.8e-20 Lymphocyte counts; LIHC cis rs7818688 0.745 rs11779282 chr8:95945487 A/G cg16049864 chr8:95962084 TP53INP1 0.57 6.26 0.32 1.17e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs796364 0.715 rs11688872 chr2:201052418 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -8.26 -0.41 3.28e-15 Schizophrenia; LIHC cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg04944784 chr2:26401820 FAM59B 0.72 9.25 0.45 2.53e-18 Gut microbiome composition (summer); LIHC cis rs727505 0.865 rs17325193 chr7:124648385 A/G cg23710748 chr7:124431027 NA -0.33 -5.88 -0.3 9.64e-9 Lewy body disease; LIHC cis rs739401 0.611 rs417957 chr11:3046231 A/G cg25174290 chr11:3078921 CARS 0.59 9.04 0.44 1.19e-17 Longevity; LIHC cis rs1816752 0.905 rs6490929 chr13:25014252 G/A cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs12908161 0.959 rs34342559 chr15:85331271 A/G cg12863693 chr15:85201151 NMB 0.45 6.33 0.32 7.53e-10 Schizophrenia; LIHC cis rs6089584 1.000 rs3787425 chr20:60559256 C/T cg06108461 chr20:60628389 TAF4 -0.88 -13.71 -0.6 2.16e-34 Body mass index; LIHC cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg08687515 chr19:58661962 ZNF329 0.97 7.4 0.37 1.08e-12 Cholesterol, total; LIHC cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg20607798 chr8:58055168 NA 0.66 8.06 0.4 1.32e-14 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.5 -0.38 5.41e-13 Initial pursuit acceleration; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg16103275 chr6:290800 DUSP22 0.51 6.76 0.34 5.86e-11 Menopause (age at onset); LIHC trans rs9951602 0.541 rs56882694 chr18:76647010 C/T cg02800362 chr5:177631904 HNRNPAB 0.66 10.39 0.49 3.58e-22 Obesity-related traits; LIHC cis rs17433710 0.516 rs6689396 chr1:162676698 C/T cg01063088 chr1:162760584 HSD17B7 -0.48 -6.97 -0.35 1.62e-11 Dupuytren's disease; LIHC cis rs7208859 0.673 rs73263755 chr17:29198972 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs903552 0.800 rs28470883 chr15:102000824 G/A cg25677261 chr15:102009856 PCSK6 -0.45 -5.91 -0.3 8.49e-9 Diabetic kidney disease; LIHC cis rs769267 0.965 rs1010207 chr19:19416045 T/C cg21559469 chr19:19431446 KIAA0892;SF4 0.42 5.9 0.3 8.62e-9 Tonsillectomy; LIHC cis rs3099143 0.901 rs28405838 chr15:77226053 C/G cg21673338 chr15:77095150 SCAPER -0.49 -7.07 -0.36 8.97e-12 Recalcitrant atopic dermatitis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26163374 chr17:71188695 COG1 -0.44 -6.63 -0.34 1.33e-10 Pancreatic cancer; LIHC cis rs757081 0.667 rs60173525 chr11:17259967 A/G cg15432903 chr11:17409602 KCNJ11 -0.42 -5.81 -0.3 1.41e-8 Systolic blood pressure; LIHC cis rs6598163 0.712 rs10751695 chr12:132291061 A/C cg10319629 chr12:132285459 NA 0.42 7.75 0.39 1.07e-13 Migraine; LIHC cis rs911119 1.000 rs3827142 chr20:23617007 G/A cg16589663 chr20:23618590 CST3 0.76 7.89 0.39 4.24e-14 Chronic kidney disease; LIHC cis rs9457247 0.602 rs9457262 chr6:167473685 A/G cg23791538 chr6:167370224 RNASET2 -0.52 -7.84 -0.39 5.81e-14 Crohn's disease; LIHC cis rs9309711 0.623 rs7569694 chr2:3483390 T/G cg10845886 chr2:3471009 TTC15 -0.44 -8.34 -0.41 1.87e-15 Neurofibrillary tangles; LIHC cis rs10911232 0.507 rs3934697 chr1:183027512 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.55 0.5 1e-22 Hypertriglyceridemia; LIHC cis rs1538970 0.924 rs11211111 chr1:45908782 C/T cg15605315 chr1:45957053 TESK2 -0.44 -5.76 -0.3 1.84e-8 Platelet count; LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg20295408 chr7:1910781 MAD1L1 -0.43 -6.26 -0.32 1.15e-9 Bipolar disorder and schizophrenia; LIHC cis rs7100689 1.000 rs7100689 chr10:82222178 C/A cg00277334 chr10:82204260 NA -0.64 -7.14 -0.36 5.46e-12 Post bronchodilator FEV1; LIHC cis rs904251 0.523 rs9349039 chr6:37480392 A/G cg01843034 chr6:37503916 NA -0.47 -7.99 -0.4 2.12e-14 Cognitive performance; LIHC cis rs9457247 0.663 rs1894603 chr6:167434686 C/T cg23791538 chr6:167370224 RNASET2 0.53 8.83 0.43 5.46e-17 Crohn's disease; LIHC cis rs7520050 0.581 rs3855959 chr1:46633874 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.51 7.79 0.39 8.28e-14 Red blood cell count;Reticulocyte count; LIHC cis rs244293 0.931 rs2058026 chr17:53204759 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs8081395 0.769 rs12449331 chr17:57883646 T/C cg02344993 chr17:57696989 CLTC -0.45 -7.42 -0.37 9.11e-13 White blood cell count; LIHC cis rs539514 0.539 rs1408060 chr13:76289980 G/C cg04757411 chr13:76259545 LMO7 -0.49 -8.56 -0.42 4.01e-16 Type 1 diabetes; LIHC cis rs35883536 0.935 rs12409832 chr1:101107725 A/G cg14515779 chr1:101123966 NA -0.67 -13.22 -0.58 1.65e-32 Monocyte count; LIHC trans rs10411161 0.752 rs10404812 chr19:52400691 T/C cg22319618 chr22:45562946 NUP50 -0.64 -8.67 -0.42 1.74e-16 Breast cancer; LIHC cis rs9916302 0.706 rs2338799 chr17:37513941 G/A cg07936489 chr17:37558343 FBXL20 0.85 12.19 0.55 1.26e-28 Glomerular filtration rate (creatinine); LIHC cis rs9309473 0.948 rs6719753 chr2:73749054 T/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.9 -0.35 2.48e-11 Metabolite levels; LIHC cis rs703842 1.000 rs3782130 chr12:58161898 G/C cg18357645 chr12:58087776 OS9 -0.45 -6.91 -0.35 2.45e-11 Multiple sclerosis; LIHC cis rs3809566 0.637 rs8026047 chr15:63323347 C/G cg05771511 chr15:63340396 TPM1 -0.43 -6.3 -0.32 9.34e-10 Platelet count; LIHC cis rs6963495 0.818 rs73192145 chr7:105203628 A/C cg19920283 chr7:105172520 RINT1 0.64 5.83 0.3 1.27e-8 Bipolar disorder (body mass index interaction); LIHC cis rs2153535 0.541 rs9328477 chr6:8519109 T/C cg21535247 chr6:8435926 SLC35B3 0.62 8.22 0.41 4.22e-15 Motion sickness; LIHC cis rs17685 0.535 rs41299460 chr7:75600951 G/A cg16684958 chr7:75615977 POR 0.38 5.98 0.31 5.68e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2286885 0.965 rs10819167 chr9:129241716 T/A cg15282417 chr9:129245246 FAM125B 0.4 6.75 0.34 6.27e-11 Intraocular pressure; LIHC cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg24531977 chr5:56204891 C5orf35 -0.59 -8.42 -0.41 1.08e-15 Initial pursuit acceleration; LIHC cis rs11112613 0.713 rs73184082 chr12:105951748 T/C cg03607813 chr12:105948248 NA 0.62 12.26 0.55 6.76e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs763014 0.966 rs15564 chr16:677854 G/T cg09263875 chr16:632152 PIGQ 0.58 10.38 0.49 3.95e-22 Height; LIHC cis rs2404602 0.735 rs2454450 chr15:76831236 G/A cg03037974 chr15:76606532 NA -0.64 -11.18 -0.52 6.01e-25 Blood metabolite levels; LIHC cis rs34233420 1 rs34233420 chr17:38004929 GATTT/G cg11212589 chr17:38028394 ZPBP2 0.34 6.88 0.35 2.95e-11 Lymphocyte counts; LIHC cis rs6788895 0.661 rs77431731 chr3:150489911 T/G cg07663535 chr3:150480033 SIAH2 0.58 7.24 0.36 2.9e-12 Breast cancer; LIHC cis rs7044106 0.762 rs10760115 chr9:123476952 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.07 0.51 1.56e-24 Hip circumference adjusted for BMI; LIHC cis rs1046896 0.520 rs8074086 chr17:80818460 A/C cg19500275 chr17:80737654 TBCD 0.4 5.74 0.3 2.12e-8 Glycated hemoglobin levels; LIHC cis rs798554 0.757 rs1182176 chr7:2874601 A/G cg19717773 chr7:2847554 GNA12 -0.42 -6.42 -0.33 4.6e-10 Height; LIHC cis rs28489187 0.706 rs4949890 chr1:85830632 T/C cg16011679 chr1:85725395 C1orf52 0.46 5.82 0.3 1.38e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs6502050 0.731 rs11867299 chr17:80088675 C/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC cis rs10504073 0.584 rs11784268 chr8:49956339 T/G cg00325661 chr8:49890786 NA 0.34 7.65 0.38 2.03e-13 Blood metabolite ratios; LIHC cis rs9303401 0.614 rs17175663 chr17:57108437 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.26 0.55 7.01e-29 Cognitive test performance; LIHC trans rs1814175 0.817 rs28525029 chr11:50045815 A/G cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs875971 0.545 rs17138149 chr7:65693180 A/G cg11764359 chr7:65958608 NA 0.52 7.33 0.37 1.69e-12 Aortic root size; LIHC trans rs7618501 1.000 rs11716575 chr3:49744890 A/G cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg14893161 chr1:205819251 PM20D1 0.68 9.9 0.47 1.73e-20 Menarche (age at onset); LIHC cis rs12188164 0.543 rs2434694 chr5:462734 C/T cg26076054 chr5:421317 AHRR 0.27 5.97 0.31 5.91e-9 Cystic fibrosis severity; LIHC cis rs6665290 0.904 rs1045252 chr1:227181555 A/G cg10327440 chr1:227177885 CDC42BPA -1.19 -31.38 -0.86 1.02e-102 Myeloid white cell count; LIHC trans rs7618501 1.000 rs3749241 chr3:49744392 A/G cg21582582 chr3:182698605 DCUN1D1 -0.52 -6.67 -0.34 1.03e-10 Intelligence (multi-trait analysis); LIHC cis rs55702914 0.935 rs56116936 chr2:198219217 C/A cg10820045 chr2:198174542 NA 0.38 5.74 0.3 2.06e-8 Major depression and alcohol dependence; LIHC cis rs1580019 0.885 rs1610141 chr7:32498435 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.98 16.63 0.67 6.3e-46 Cognitive ability; LIHC cis rs10791097 0.642 rs7107568 chr11:130779668 T/C cg14779329 chr11:130786720 SNX19 0.45 7.14 0.36 5.75e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg27170947 chr2:26402098 FAM59B 0.67 8.36 0.41 1.62e-15 Gut microbiome composition (summer); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20591167 chr15:99602178 NA 0.52 7.51 0.38 5.09e-13 Pancreatic cancer; LIHC cis rs67311347 1.000 rs2305522 chr3:40429358 A/G cg18306943 chr3:40428807 ENTPD3 0.33 5.72 0.3 2.35e-8 Renal cell carcinoma; LIHC cis rs8072100 0.811 rs9889709 chr17:45445229 C/T cg25173405 chr17:45401733 C17orf57 -0.44 -6.02 -0.31 4.41e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg12310025 chr6:25882481 NA -0.64 -9.14 -0.44 5.59e-18 Blood metabolite levels; LIHC cis rs910316 0.737 rs175045 chr14:75475275 A/C cg11812906 chr14:75593930 NEK9 -0.74 -13.84 -0.6 6.48e-35 Height; LIHC cis rs55637647 0.515 rs7206699 chr16:88523815 A/G cg06126698 chr16:88535609 ZFPM1 -0.36 -6.07 -0.31 3.41e-9 Testicular germ cell tumor; LIHC cis rs9303401 0.555 rs8073699 chr17:57236317 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.43 6.41 0.33 4.79e-10 Cognitive test performance; LIHC cis rs6750047 0.932 rs2116232 chr2:38268718 C/A cg07380506 chr2:38303506 CYP1B1 0.49 6.03 0.31 4.32e-9 Cutaneous malignant melanoma;Melanoma; LIHC trans rs459571 0.839 rs2519831 chr9:136886257 T/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.6 -9.37 -0.45 9.91e-19 Platelet distribution width; LIHC cis rs6964587 1.000 rs11971885 chr7:91674807 T/C cg17063962 chr7:91808500 NA 1.0 19.19 0.72 3.22e-56 Breast cancer; LIHC cis rs6785206 1.000 rs6785206 chr3:128412024 A/G cg16766828 chr3:128327626 NA -0.64 -7.0 -0.35 1.38e-11 Lymphocyte percentage of white cells; LIHC cis rs9640161 0.830 rs76741564 chr7:150059529 A/T cg17279839 chr7:150038598 RARRES2 0.39 7.93 0.39 3.22e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs9326248 0.817 rs1242127 chr11:117076564 A/G cg11861562 chr11:117069780 TAGLN -0.45 -7.46 -0.37 7.15e-13 Blood protein levels; LIHC cis rs2282802 0.685 rs13359519 chr5:139654664 G/A cg26211634 chr5:139558579 C5orf32 0.39 6.03 0.31 4.29e-9 Intelligence (multi-trait analysis); LIHC trans rs11039798 0.610 rs11530356 chr11:48836290 C/A cg15704280 chr7:45808275 SEPT13 0.64 6.65 0.34 1.14e-10 Axial length; LIHC cis rs2153535 0.580 rs9505467 chr6:8520219 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.82 0.43 5.8e-17 Motion sickness; LIHC cis rs7520050 0.966 rs1707340 chr1:46514942 T/C cg03146154 chr1:46216737 IPP -0.36 -5.94 -0.31 7.06e-9 Red blood cell count;Reticulocyte count; LIHC trans rs7644516 0.646 rs2052761 chr3:25924669 A/G cg10355455 chr12:6961187 USP5;CDCA3 -0.48 -6.31 -0.32 8.55e-10 DNA methylation (variation); LIHC cis rs7707921 0.881 rs73134709 chr5:81268499 G/A cg15871215 chr5:81402204 ATG10 -0.65 -6.45 -0.33 3.86e-10 Breast cancer; LIHC trans rs783540 0.632 rs17356528 chr15:83305550 A/G cg18393722 chr15:85113863 UBE2QP1 -0.43 -6.74 -0.34 6.85e-11 Schizophrenia; LIHC cis rs2832191 0.791 rs2065270 chr21:30485420 T/C cg08807101 chr21:30365312 RNF160 -0.63 -9.97 -0.47 1.03e-20 Dental caries; LIHC cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg02993280 chr1:107599747 PRMT6 0.68 11.0 0.51 2.75e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.25 -0.32 1.22e-9 Total body bone mineral density; LIHC cis rs10751667 0.961 rs10902263 chr11:992691 A/C cg10932868 chr11:921992 NA -0.33 -6.1 -0.31 2.84e-9 Alzheimer's disease (late onset); LIHC cis rs741677 0.702 rs9893847 chr17:489043 C/G cg15660573 chr17:549704 VPS53 -0.52 -8.49 -0.42 6.62e-16 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs3540 0.597 rs7498113 chr15:91051192 C/G cg22089800 chr15:90895588 ZNF774 -0.55 -7.96 -0.4 2.53e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC trans rs877282 1.000 rs7100358 chr10:773681 G/A cg22713356 chr15:30763199 NA 1.28 11.42 0.53 8.49e-26 Uric acid levels; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.46 -7.07 -0.36 8.63e-12 Total body bone mineral density; LIHC trans rs561341 0.941 rs72825746 chr17:30364610 G/A cg20587970 chr11:113659929 NA -1.44 -12.1 -0.55 2.8e-28 Hip circumference adjusted for BMI; LIHC cis rs12291225 0.585 rs10832246 chr11:14380828 G/A cg19336497 chr11:14380999 RRAS2 -0.67 -14.13 -0.61 4.85e-36 Sense of smell; LIHC cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg00684032 chr4:1343700 KIAA1530 0.5 7.3 0.37 2.01e-12 Obesity-related traits; LIHC cis rs2404602 0.735 rs11635463 chr15:76762986 C/T cg03037974 chr15:76606532 NA -0.63 -10.88 -0.51 7.1e-24 Blood metabolite levels; LIHC cis rs6424115 0.708 rs13551 chr1:24180962 T/C cg15997130 chr1:24165203 NA -0.36 -6.54 -0.33 2.31e-10 Immature fraction of reticulocytes; LIHC cis rs11031096 0.503 rs67065286 chr11:4105273 A/C cg18678763 chr11:4115507 RRM1 -0.59 -8.7 -0.43 1.41e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs12497850 0.931 rs28642807 chr3:48926816 A/G cg07636037 chr3:49044803 WDR6 0.93 16.74 0.67 2.27e-46 Parkinson's disease; LIHC cis rs1451375 0.794 rs11238133 chr7:50542914 A/C cg14593290 chr7:50529359 DDC -0.48 -7.93 -0.39 3.18e-14 Malaria; LIHC cis rs28374715 0.662 rs16971558 chr15:41458619 G/A cg18705301 chr15:41695430 NDUFAF1 -0.79 -8.7 -0.43 1.43e-16 Ulcerative colitis; LIHC cis rs9393692 0.905 rs9358919 chr6:26287862 C/T cg00631329 chr6:26305371 NA -0.45 -7.61 -0.38 2.69e-13 Educational attainment; LIHC cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.85e-26 Platelet count; LIHC cis rs12477438 0.520 rs6741773 chr2:99738962 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.38 0.77 5.56e-69 Chronic sinus infection; LIHC cis rs7927771 1.000 rs10838738 chr11:47663049 A/G cg20135002 chr11:47629003 NA -0.58 -10.11 -0.48 3.37e-21 Subjective well-being; LIHC trans rs10411161 0.690 rs7252336 chr19:52389514 C/T cg22319618 chr22:45562946 NUP50 -0.62 -8.49 -0.42 6.32e-16 Breast cancer; LIHC cis rs903552 0.935 rs8041582 chr15:102005851 G/A cg06707286 chr15:102010195 PCSK6 -0.44 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC cis rs10744422 1.000 rs7959441 chr12:123363825 C/T cg18912006 chr12:123335444 HIP1R -0.59 -6.82 -0.35 4.18e-11 Schizophrenia; LIHC cis rs7529073 0.815 rs1431984 chr1:214148628 A/G cg24083324 chr1:214162604 PROX1 -0.56 -8.55 -0.42 4.16e-16 Schizophrenia; LIHC cis rs7914558 0.966 rs10450373 chr10:104728616 T/C cg15744005 chr10:104629667 AS3MT -0.4 -9.1 -0.44 7.83e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07546262 chr12:54753490 NA 0.47 6.87 0.35 2.97e-11 Pancreatic cancer; LIHC cis rs1355223 0.583 rs2915178 chr11:34878051 C/T cg06937548 chr11:34938143 PDHX;APIP 0.42 5.94 0.31 7.11e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.51 0.38 5.35e-13 Prudent dietary pattern; LIHC cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg15691649 chr6:25882328 NA 0.45 5.76 0.3 1.92e-8 Intelligence (multi-trait analysis); LIHC cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3770081 1.000 rs3731819 chr2:86368641 C/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.86 -9.06 -0.44 9.92e-18 Facial emotion recognition (sad faces); LIHC cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg08677398 chr8:58056175 NA 0.41 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19386303 chr19:47104863 CALM3 0.6 7.85 0.39 5.26e-14 Lung function (FEV1/FVC); LIHC cis rs8180040 0.764 rs12630534 chr3:47001043 T/C cg27129171 chr3:47204927 SETD2 0.62 10.79 0.5 1.46e-23 Colorectal cancer; LIHC cis rs5769765 0.908 rs9616388 chr22:50313438 T/C cg09182678 chr22:50328711 NA -0.44 -6.24 -0.32 1.32e-9 Schizophrenia; LIHC cis rs7772486 0.790 rs4435956 chr6:146232403 G/C cg23711669 chr6:146136114 FBXO30 -0.64 -11.16 -0.52 7.22e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs9768139 0.683 rs72505558 chr7:158113215 A/G cg06219351 chr7:158114137 PTPRN2 -0.2 -5.72 -0.3 2.36e-8 Calcium levels; LIHC cis rs74181299 0.533 rs3732096 chr2:65358083 C/T cg05010058 chr2:65284262 CEP68 -0.37 -6.02 -0.31 4.38e-9 Pulse pressure; LIHC cis rs7173389 0.530 rs11636535 chr15:73681648 T/C cg01796676 chr15:73680284 NA 0.53 8.58 0.42 3.38e-16 Resting heart rate; LIHC cis rs11098499 0.954 rs6848389 chr4:120402622 A/G cg09307838 chr4:120376055 NA 0.76 12.08 0.55 3.16e-28 Corneal astigmatism; LIHC cis rs7927592 0.913 rs3740629 chr11:68343593 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.22 -0.32 1.46e-9 Total body bone mineral density; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg13409248 chr3:40428643 ENTPD3 0.47 7.75 0.39 1.02e-13 Renal cell carcinoma; LIHC trans rs800082 0.839 rs11714177 chr3:144312862 T/C cg24215973 chr2:240111563 HDAC4 -0.49 -6.81 -0.35 4.51e-11 Smoking behavior; LIHC cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.53 0.49 1.25e-22 Colorectal cancer; LIHC cis rs11123170 0.640 rs931472 chr2:113969948 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.48 -6.09 -0.31 3.03e-9 Renal function-related traits (BUN); LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg23131131 chr22:24373011 LOC391322 -0.61 -8.59 -0.42 3.1e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9916302 0.904 rs9898170 chr17:37510092 T/C cg07936489 chr17:37558343 FBXL20 0.81 12.96 0.57 1.6e-31 Glomerular filtration rate (creatinine); LIHC cis rs7617773 0.962 rs6797587 chr3:48197614 A/G cg11946769 chr3:48343235 NME6 -0.62 -8.03 -0.4 1.63e-14 Coronary artery disease; LIHC cis rs6502050 0.765 rs6502075 chr17:80121813 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs11122272 0.735 rs722302 chr1:231480152 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -10.95 -0.51 4e-24 Hemoglobin concentration; LIHC cis rs9649465 0.967 rs12539091 chr7:123291314 C/T cg03229431 chr7:123269106 ASB15 -0.39 -8.22 -0.41 4.29e-15 Migraine; LIHC cis rs2404602 0.684 rs8029283 chr15:76837140 A/G cg03037974 chr15:76606532 NA -0.61 -10.21 -0.48 1.6e-21 Blood metabolite levels; LIHC cis rs1691799 0.899 rs1168301 chr12:66736771 C/T cg16791601 chr12:66731901 HELB -0.54 -12.96 -0.57 1.61e-31 White blood cell count (basophil); LIHC cis rs769267 0.965 rs2965191 chr19:19453521 T/G cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.27 -0.32 1.11e-9 Tonsillectomy; LIHC cis rs7508 0.509 rs441606 chr8:17903046 C/T cg01800426 chr8:17659068 MTUS1 0.36 5.72 0.3 2.27e-8 Atrial fibrillation; LIHC cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.9 9.24 0.45 2.64e-18 Platelet count; LIHC cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg00149659 chr3:10157352 C3orf10 0.61 6.67 0.34 1.06e-10 Alzheimer's disease; LIHC cis rs10870270 1.000 rs7898755 chr10:133777122 G/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.77 -0.57 8.31e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9790314 0.967 rs7623206 chr3:160971518 G/A cg04691961 chr3:161091175 C3orf57 -0.4 -6.4 -0.33 5.07e-10 Morning vs. evening chronotype; LIHC cis rs986417 0.748 rs9989223 chr14:60942525 C/A cg27398547 chr14:60952738 C14orf39 0.73 8.7 0.43 1.37e-16 Gut microbiota (bacterial taxa); LIHC cis rs853679 0.517 rs9393898 chr6:28130376 G/T cg16479474 chr6:28041457 NA 0.45 6.51 0.33 2.6200000000000003e-10 Depression; LIHC cis rs10504229 1.000 rs72652906 chr8:58188360 C/A cg02290350 chr8:58132656 NA 0.38 7.9 0.39 3.9e-14 Developmental language disorder (linguistic errors); LIHC cis rs2439831 0.850 rs28707214 chr15:44131623 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.73 0.34 7.11e-11 Lung cancer in ever smokers; LIHC cis rs6450176 1.000 rs3776705 chr5:53304955 T/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.66 -0.62 4.37e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1577917 0.958 rs36053156 chr6:86575509 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.38 -0.37 1.21e-12 Response to antipsychotic treatment; LIHC cis rs9467773 0.587 rs10946813 chr6:26345141 A/G cg09904177 chr6:26538194 HMGN4 0.36 5.82 0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.729 rs505533 chr22:41864216 A/C cg03806693 chr22:41940476 POLR3H 0.56 7.45 0.37 7.53e-13 Vitiligo; LIHC cis rs60871478 0.635 rs4311567 chr7:792295 T/C cg04727924 chr7:799746 HEATR2 -0.59 -7.89 -0.39 4.22e-14 Cerebrospinal P-tau181p levels; LIHC cis rs11122272 0.735 rs910822 chr1:231498721 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.83 -0.51 1.06e-23 Hemoglobin concentration; LIHC cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg21724239 chr8:58056113 NA 0.55 6.82 0.35 4.09e-11 Developmental language disorder (linguistic errors); LIHC trans rs7193541 0.646 rs4888267 chr16:74687906 A/G cg23598604 chr1:99732472 LPPR4 -0.3 -6.27 -0.32 1.09e-9 Multiple myeloma; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07067085 chr12:120638762 RPLP0 0.36 6.21 0.32 1.51e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs61931739 0.500 rs11052994 chr12:34065843 C/T cg26384229 chr12:38710491 ALG10B 0.49 6.82 0.35 4.04e-11 Morning vs. evening chronotype; LIHC cis rs7772486 0.790 rs2254288 chr6:146204470 G/A cg05347473 chr6:146136440 FBXO30 0.36 5.87 0.3 1.03e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1568889 0.774 rs11030235 chr11:28212375 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.19 0.61 3.05e-36 Bipolar disorder; LIHC trans rs4650994 0.525 rs2224811 chr1:178544323 C/T cg05059571 chr16:84539110 KIAA1609 0.45 7.41 0.37 9.97e-13 HDL cholesterol levels;HDL cholesterol; LIHC trans rs13067593 1.000 rs13087629 chr3:188568042 C/T cg08898155 chr7:95026097 PON3 0.73 6.05 0.31 3.85e-9 Immune reponse to smallpox (secreted IFN-alpha); LIHC cis rs9916302 0.904 rs600010 chr17:37433517 T/C cg00129232 chr17:37814104 STARD3 -0.39 -6.26 -0.32 1.17e-9 Glomerular filtration rate (creatinine); LIHC cis rs7192750 0.538 rs8054403 chr16:71990573 G/A cg06353428 chr16:71660113 MARVELD3 0.8 9.06 0.44 1.02e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs6840360 0.571 rs7695866 chr4:152488110 G/A cg22705602 chr4:152727874 NA -0.33 -6.55 -0.33 2.13e-10 Intelligence (multi-trait analysis); LIHC cis rs1555322 0.530 rs2275275 chr20:33872311 G/C cg08210727 chr20:33865349 NA 0.51 5.89 0.3 9.43e-9 Attention deficit hyperactivity disorder; LIHC cis rs896854 0.654 rs896847 chr8:95972551 G/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.83 -0.39 6.02e-14 Type 2 diabetes; LIHC cis rs6912958 0.514 rs7767449 chr6:87887985 A/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.34 -6.4 -0.33 5.01e-10 Monocyte percentage of white cells; LIHC cis rs7249142 0.549 rs62135499 chr19:19294237 T/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.35 -5.77 -0.3 1.74e-8 IgG glycosylation; LIHC cis rs1448094 0.549 rs57614821 chr12:86235361 A/C cg02569458 chr12:86230093 RASSF9 0.48 6.44 0.33 3.97e-10 Major depressive disorder; LIHC cis rs7542091 0.704 rs7550330 chr1:210044587 G/A cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.52e-9 Monobrow; LIHC cis rs2191566 1.000 rs367499 chr19:44504981 G/A cg20607764 chr19:44506953 ZNF230 0.42 6.68 0.34 9.74e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs9902453 0.868 rs9890075 chr17:28470464 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 10.01 0.48 7.14e-21 Coffee consumption (cups per day); LIHC cis rs2439831 0.850 rs28718261 chr15:44043793 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.52 0.33 2.46e-10 Lung cancer in ever smokers; LIHC cis rs600806 0.813 rs6664236 chr1:109986672 C/A cg16275483 chr1:110013120 SYPL2 -0.48 -5.91 -0.3 8.48e-9 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.623 rs56812022 chr17:29068733 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs611744 0.967 rs595266 chr8:109193784 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs25645 0.502 rs7207600 chr17:38091660 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.44 -6.47 -0.33 3.35e-10 Myeloid white cell count; LIHC trans rs61931739 0.500 rs7955933 chr12:34473608 A/G cg26384229 chr12:38710491 ALG10B 0.61 7.49 0.38 5.86e-13 Morning vs. evening chronotype; LIHC cis rs2574704 0.816 rs2442777 chr3:11652331 G/A cg15876825 chr3:11651881 VGLL4 -0.5 -8.05 -0.4 1.42e-14 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01676552 chr8:146156633 ZNF16 0.44 6.68 0.34 9.61e-11 Pancreatic cancer; LIHC cis rs9291683 0.588 rs3756237 chr4:10013378 G/A cg11266682 chr4:10021025 SLC2A9 0.33 7.14 0.36 5.5e-12 Bone mineral density; LIHC cis rs16828019 0.777 rs35496942 chr1:41488904 G/A cg03387723 chr1:41708464 SCMH1 -0.4 -6.27 -0.32 1.07e-9 Intelligence (multi-trait analysis); LIHC cis rs208520 0.731 rs12206488 chr6:66999917 G/T cg07460842 chr6:66804631 NA 0.69 6.9 0.35 2.49e-11 Exhaled nitric oxide output; LIHC cis rs748404 0.660 rs690012 chr15:43719755 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.35 0.37 1.45e-12 Lung cancer; LIHC cis rs12744310 1.000 rs12037657 chr1:41764175 C/T cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7085104 0.572 rs284857 chr10:104574063 C/T cg15744005 chr10:104629667 AS3MT 0.36 7.82 0.39 6.59e-14 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs765787 0.530 rs10467979 chr15:45521270 G/A cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.73 -0.3 2.15e-8 Uric acid levels; LIHC cis rs34375054 0.525 rs1080910 chr12:125608492 T/C cg25124228 chr12:125621409 AACS -0.5 -9.41 -0.45 7.45e-19 Post bronchodilator FEV1/FVC ratio; LIHC cis rs9303401 0.659 rs12150536 chr17:56640834 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.89 11.48 0.53 4.89e-26 Cognitive test performance; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.06 0.61 9.8e-36 Prudent dietary pattern; LIHC cis rs2153535 0.580 rs6912193 chr6:8456306 T/G cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs2549003 1.000 rs2070727 chr5:131820275 C/A cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.25e-20 Asthma (sex interaction); LIHC trans rs1814175 0.740 rs10839439 chr11:49918240 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs3008870 0.920 rs1925413 chr1:67417101 T/C cg02640540 chr1:67518911 SLC35D1 0.43 5.9 0.3 8.77e-9 Lymphocyte percentage of white cells; LIHC cis rs4243830 0.850 rs1114661 chr1:6596871 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.95 -12.12 -0.55 2.25e-28 Body mass index; LIHC cis rs10504073 0.647 rs62507245 chr8:50006939 A/T cg00325661 chr8:49890786 NA 0.32 7.18 0.36 4.41e-12 Blood metabolite ratios; LIHC cis rs9858542 0.953 rs11719996 chr3:49525958 T/C cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6754311 0.731 rs745500 chr2:136583192 G/A cg15123519 chr2:136567270 LCT 0.45 9.36 0.45 1.07e-18 Mosquito bite size; LIHC cis rs7193541 0.682 rs28681530 chr16:74682496 C/T cg01733217 chr16:74700730 RFWD3 0.92 22.66 0.77 4.62e-70 Multiple myeloma; LIHC cis rs9814567 1.000 rs1534026 chr3:134284767 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10792665 0.517 rs7925208 chr11:82561979 G/A cg24227371 chr11:82718527 RAB30 -0.26 -6.1 -0.31 2.9e-9 Obesity-related traits; LIHC cis rs12477438 0.501 rs6727749 chr2:99793590 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg26338869 chr17:61819248 STRADA -0.59 -8.77 -0.43 8.59e-17 Prudent dietary pattern; LIHC cis rs12142240 0.698 rs17361936 chr1:46862893 C/T cg14993813 chr1:46806288 NSUN4 -0.66 -5.95 -0.31 6.53e-9 Menopause (age at onset); LIHC cis rs7827545 0.644 rs3739427 chr8:135524938 T/C cg09855544 chr8:135498122 ZFAT -0.51 -8.63 -0.42 2.38e-16 Hypertension (SNP x SNP interaction); LIHC cis rs13256369 1.000 rs9329166 chr8:8576655 C/T cg18904891 chr8:8559673 CLDN23 0.67 11.32 0.52 1.95e-25 Obesity-related traits; LIHC cis rs12586317 0.620 rs17103042 chr14:35575428 T/C cg05294307 chr14:35346193 BAZ1A -0.46 -6.8 -0.35 4.74e-11 Psoriasis; LIHC trans rs2727020 0.729 rs588458 chr11:49214048 C/A cg15704280 chr7:45808275 SEPT13 0.88 16.13 0.66 6.19e-44 Coronary artery disease; LIHC cis rs9341808 0.727 rs9352809 chr6:80999316 C/T cg08355045 chr6:80787529 NA 0.33 6.72 0.34 7.76e-11 Sitting height ratio; LIHC cis rs1707322 0.721 rs4559551 chr1:46167533 T/C cg06784218 chr1:46089804 CCDC17 0.42 7.8 0.39 7.82e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3749237 0.595 rs12489092 chr3:49550914 G/C cg06212747 chr3:49208901 KLHDC8B 0.45 5.92 0.3 7.8e-9 Resting heart rate; LIHC cis rs860295 0.812 rs4278368 chr1:155722557 G/A cg02153340 chr1:155202674 NA -0.35 -6.37 -0.33 6.2e-10 Body mass index; LIHC cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs208520 1.000 rs12194996 chr6:66973366 G/C cg07460842 chr6:66804631 NA 0.66 6.97 0.35 1.65e-11 Exhaled nitric oxide output; LIHC cis rs12477438 0.501 rs11683107 chr2:99759235 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.6 11.19 0.52 5.77e-25 Chronic sinus infection; LIHC cis rs253664 0.796 rs799328 chr3:138082705 T/G cg25188949 chr3:137893707 DBR1 -0.57 -5.77 -0.3 1.8e-8 Body mass index; LIHC cis rs6088590 0.931 rs12625149 chr20:33425812 A/C cg06115741 chr20:33292138 TP53INP2 -0.59 -8.37 -0.41 1.49e-15 Coronary artery disease; LIHC cis rs1577917 0.958 rs13213899 chr6:86473140 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.97 -0.51 3.35e-24 Response to antipsychotic treatment; LIHC cis rs10751667 1.000 rs7394449 chr11:962190 T/C cg06064525 chr11:970664 AP2A2 -0.49 -12.33 -0.55 3.67e-29 Alzheimer's disease (late onset); LIHC cis rs787274 1.000 rs72768411 chr9:115502670 C/A cg13803584 chr9:115635662 SNX30 0.6 6.34 0.32 7.17e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02133430 chr8:54573841 NA 0.45 6.54 0.33 2.22e-10 Immature fraction of reticulocytes; LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg24846343 chr22:24311635 DDTL 0.61 11.28 0.52 2.56e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11718455 0.960 rs17076254 chr3:44000361 C/T cg08738300 chr3:44038990 NA 0.51 8.99 0.44 1.68e-17 Coronary artery disease; LIHC cis rs55665837 0.701 rs10160597 chr11:14603992 G/A cg16394018 chr11:14927549 NA 0.41 5.84 0.3 1.24e-8 Vitamin D levels; LIHC cis rs1552244 0.882 rs67762674 chr3:10014485 C/T cg00149659 chr3:10157352 C3orf10 0.53 6.1 0.31 2.93e-9 Alzheimer's disease; LIHC cis rs8062405 0.755 rs2077031 chr16:28603168 T/A cg16576597 chr16:28551801 NUPR1 0.48 7.3 0.37 1.99e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4148883 0.651 rs2851301 chr4:100010127 C/T cg12011299 chr4:100065546 ADH4 0.35 7.14 0.36 5.5e-12 Alcohol dependence; LIHC cis rs11864453 0.963 rs7185215 chr16:72034864 T/C cg01557791 chr16:72042693 DHODH -0.72 -11.35 -0.52 1.45e-25 Fibrinogen levels; LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg12016809 chr21:47604291 C21orf56 0.49 7.6 0.38 2.86e-13 Testicular germ cell tumor; LIHC cis rs11764590 0.651 rs12673687 chr7:2081873 C/T cg23422044 chr7:1970798 MAD1L1 -0.47 -7.24 -0.36 2.91e-12 Neuroticism; LIHC cis rs76419734 0.558 rs7696836 chr4:106583826 C/T cg24545054 chr4:106630052 GSTCD;INTS12 0.7 8.69 0.43 1.55e-16 Post bronchodilator FEV1; LIHC cis rs1534166 0.602 rs3817524 chr3:133526403 C/T cg27366882 chr3:133540807 NA -0.42 -7.01 -0.35 1.25e-11 Alcohol consumption (transferrin glycosylation); LIHC cis rs597539 0.616 rs513476 chr11:68698996 C/T cg06028808 chr11:68637592 NA 0.45 5.8 0.3 1.47e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs9790314 0.934 rs461638 chr3:161103166 A/G cg04691961 chr3:161091175 C3orf57 -0.41 -6.51 -0.33 2.64e-10 Morning vs. evening chronotype; LIHC cis rs2574704 0.851 rs2437689 chr3:11660766 C/T cg15876825 chr3:11651881 VGLL4 -0.49 -7.92 -0.39 3.36e-14 Body mass index; LIHC cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg20295408 chr7:1910781 MAD1L1 -0.44 -6.49 -0.33 3.09e-10 Bipolar disorder and schizophrenia; LIHC cis rs72781680 0.851 rs72796397 chr2:24178211 T/A cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs10752881 0.967 rs8179284 chr1:182974707 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Colorectal cancer; LIHC cis rs9640161 0.659 rs7781827 chr7:150008858 T/C cg10018233 chr7:150070692 REPIN1 0.49 7.97 0.4 2.35e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs9790314 0.686 rs2306061 chr3:160787502 C/T cg03342759 chr3:160939853 NMD3 -0.65 -8.7 -0.43 1.38e-16 Morning vs. evening chronotype; LIHC cis rs6545883 1.000 rs778763 chr2:61785639 C/G cg15711740 chr2:61764176 XPO1 -0.43 -6.01 -0.31 4.68e-9 Tuberculosis; LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg07424592 chr7:64974309 NA -0.46 -6.9 -0.35 2.46e-11 Calcium levels; LIHC cis rs1997103 0.911 rs11238361 chr7:55395981 A/G cg17469321 chr7:55412551 NA 0.48 7.06 0.36 9.58e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs362296 0.661 rs3095077 chr4:3265710 A/G cg06533319 chr4:3265114 C4orf44 -0.34 -6.63 -0.34 1.3e-10 Parental longevity (mother's age at death); LIHC cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg19723775 chr5:179050963 HNRNPH1 -0.39 -6.22 -0.32 1.45e-9 Lung cancer; LIHC cis rs1789 0.903 rs4470622 chr4:15674175 T/G cg16509355 chr4:15471240 CC2D2A -0.45 -6.9 -0.35 2.55e-11 Blood protein levels; LIHC cis rs1577917 1.000 rs10455456 chr6:86670322 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.08 -0.48 4.13e-21 Response to antipsychotic treatment; LIHC cis rs9303401 0.659 rs34351230 chr17:56782555 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs11711311 0.712 rs6795099 chr3:113338782 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.32 -5.91 -0.3 8.32e-9 IgG glycosylation; LIHC cis rs61677309 1.000 rs56357739 chr11:118158507 A/G cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs1580019 0.922 rs34545272 chr7:32460630 C/T cg07520158 chr7:32535189 LSM5;AVL9 0.48 6.45 0.33 3.71e-10 Cognitive ability; LIHC cis rs58688157 0.705 rs936469 chr11:606749 G/A cg16486109 chr11:613632 IRF7 0.58 6.2 0.32 1.66e-9 Systemic lupus erythematosus; LIHC cis rs9911578 1.000 rs2333332 chr17:56631054 A/G cg12560992 chr17:57184187 TRIM37 -0.97 -17.73 -0.69 2.51e-50 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg26774971 chr6:158994407 TMEM181 0.42 6.17 0.32 1.98e-9 Longevity; LIHC cis rs9560113 0.960 rs61967677 chr13:112174044 A/G cg14154082 chr13:112174009 NA 0.29 6.1 0.31 2.81e-9 Menarche (age at onset); LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg02951883 chr7:2050386 MAD1L1 -0.78 -13.94 -0.6 2.86e-35 Bipolar disorder and schizophrenia; LIHC cis rs911119 1.000 rs3827143 chr20:23619617 A/G cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC trans rs11098499 0.954 rs13107475 chr4:120393011 A/T cg25214090 chr10:38739885 LOC399744 0.58 9.55 0.46 2.57e-19 Corneal astigmatism; LIHC cis rs11971779 0.680 rs10274480 chr7:139052428 T/C cg07862535 chr7:139043722 LUC7L2 0.57 9.62 0.46 1.46e-19 Diisocyanate-induced asthma; LIHC cis rs12711979 0.765 rs13030772 chr2:3821280 T/C cg17052675 chr2:3827356 NA -0.42 -7.2 -0.36 3.85e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03076073 chr11:64009400 FKBP2 0.44 6.12 0.31 2.63e-9 Lung function (FEV1/FVC); LIHC cis rs765787 0.530 rs11639403 chr15:45538350 A/G cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs1448094 0.512 rs6539928 chr12:86244920 G/A cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs7824557 0.628 rs3779891 chr8:11183505 G/A cg21775007 chr8:11205619 TDH 0.6 9.93 0.47 1.39e-20 Retinal vascular caliber; LIHC cis rs78456975 1.000 rs55761535 chr2:1561450 A/G cg01028140 chr2:1542097 TPO -0.52 -6.23 -0.32 1.4e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs6752107 1.000 rs2289474 chr2:234181848 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.55 8.54 0.42 4.46e-16 Crohn's disease;Inflammatory bowel disease; LIHC cis rs765787 0.530 rs2458224 chr15:45522130 T/C cg25801113 chr15:45476975 SHF 0.38 6.51 0.33 2.69e-10 Uric acid levels; LIHC cis rs9640161 0.663 rs1916932 chr7:150021644 T/C cg17279839 chr7:150038598 RARRES2 0.5 10.59 0.5 7.42e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs3736485 0.903 rs7165887 chr15:51750846 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.35 -0.32 6.98e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs67460515 0.506 rs935497 chr3:160600563 A/G cg03342759 chr3:160939853 NMD3 -0.48 -6.82 -0.35 4.21e-11 Parkinson's disease; LIHC cis rs10744422 0.925 rs897391 chr12:123326374 G/A cg07706471 chr12:123319906 HIP1R -0.57 -7.62 -0.38 2.57e-13 Schizophrenia; LIHC cis rs12497850 0.931 rs7430198 chr3:48988760 T/C cg06212747 chr3:49208901 KLHDC8B 0.56 7.15 0.36 5.31e-12 Parkinson's disease; LIHC cis rs6754311 0.551 rs2304599 chr2:136528004 C/G cg07305463 chr2:136567211 LCT 0.36 6.55 0.33 2.13e-10 Mosquito bite size; LIHC cis rs2304069 0.954 rs4705408 chr5:149412545 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.98 -12.87 -0.57 3.4e-31 HIV-1 control; LIHC cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg21664854 chr7:1097933 C7orf50;GPR146 0.77 6.04 0.31 4e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4268898 1.000 rs10165445 chr2:24441698 C/T cg06627628 chr2:24431161 ITSN2 0.5 7.24 0.36 2.96e-12 Asthma; LIHC cis rs116095464 0.558 rs11959126 chr5:283880 T/G cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs965469 1.000 rs2281500 chr20:3262824 C/T cg25506879 chr20:3388711 C20orf194 -0.55 -6.66 -0.34 1.1e-10 IFN-related cytopenia; LIHC cis rs116095464 0.558 rs34629844 chr5:200829 A/G cg22496380 chr5:211416 CCDC127 -1.19 -10.59 -0.5 7.59e-23 Breast cancer; LIHC cis rs3981351 0.528 rs12768908 chr10:115443894 C/T cg24846397 chr10:115438155 CASP7 -0.47 -8.0 -0.4 1.97e-14 Obesity-related traits; LIHC cis rs6988636 1.000 rs13259806 chr8:124190103 A/T cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs6089829 0.962 rs1060490 chr20:61665871 A/G cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs1062177 1.000 rs892006 chr5:151180890 G/T cg00977110 chr5:151150581 G3BP1 0.53 6.87 0.35 3.04e-11 Preschool internalizing problems; LIHC cis rs67311347 1.000 rs897117 chr3:40437294 C/T cg16822855 chr3:40428330 ENTPD3 -0.32 -5.86 -0.3 1.11e-8 Renal cell carcinoma; LIHC cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg21724239 chr8:58056113 NA 0.5 6.68 0.34 9.98e-11 Developmental language disorder (linguistic errors); LIHC cis rs425277 1.000 rs385039 chr1:2077409 C/T cg24578937 chr1:2090814 PRKCZ -0.5 -9.24 -0.45 2.66e-18 Height; LIHC cis rs3617 0.573 rs2336667 chr3:52916363 C/T cg11645453 chr3:52864694 ITIH4 -0.23 -6.11 -0.31 2.74e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.520 rs55967509 chr8:57992448 A/G cg20607798 chr8:58055168 NA 0.45 5.98 0.31 5.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs798554 0.797 rs1182183 chr7:2873136 C/T cg19717773 chr7:2847554 GNA12 -0.43 -6.58 -0.34 1.76e-10 Height; LIHC cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg11279151 chr3:101281821 RG9MTD1 0.53 7.92 0.39 3.35e-14 Colonoscopy-negative controls vs population controls; LIHC cis rs968567 0.906 rs61897793 chr11:61599347 G/A cg06781209 chr11:61594997 FADS2 -0.7 -6.52 -0.33 2.48e-10 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs1577917 0.883 rs1415749 chr6:86779084 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.39 7.09 0.36 7.64e-12 Response to antipsychotic treatment; LIHC cis rs7617773 0.643 rs78159520 chr3:48349023 T/C cg11946769 chr3:48343235 NME6 0.91 11.48 0.53 5.1e-26 Coronary artery disease; LIHC cis rs2257205 0.667 rs4340382 chr17:56738919 G/A cg12560992 chr17:57184187 TRIM37 0.71 7.79 0.39 8.05e-14 Pancreatic cancer; LIHC cis rs35306767 0.903 rs11253458 chr10:882843 T/C cg20503657 chr10:835505 NA 1.11 12.64 0.56 2.57e-30 Eosinophil percentage of granulocytes; LIHC cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.87 0.3 1.05e-8 Menopause (age at onset); LIHC cis rs9378688 1.000 rs9378686 chr6:2217173 G/A cg12303981 chr6:2244766 GMDS -0.5 -6.34 -0.32 7.23e-10 Caudate nucleus volume; LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs992157 0.585 rs62182795 chr2:219100202 C/T cg00012203 chr2:219082015 ARPC2 -0.88 -15.33 -0.64 9.23e-41 Colorectal cancer; LIHC cis rs2834188 0.924 rs2040107 chr21:34675962 C/G cg14352951 chr21:34696688 IFNAR1 -0.43 -6.2 -0.32 1.58e-9 Narcolepsy; LIHC cis rs3859192 0.599 rs2302777 chr17:38179492 A/G cg17467752 chr17:38218738 THRA -0.5 -8.67 -0.42 1.81e-16 White blood cell count; LIHC cis rs4908768 0.817 rs11577530 chr1:8743444 C/T cg20416874 chr1:8611966 RERE 0.5 6.95 0.35 1.9e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6570726 0.846 rs7762536 chr6:145923145 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.56 0.53 2.5e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs7659604 0.605 rs1507994 chr4:122749541 C/T cg19748678 chr4:122722346 EXOSC9 0.56 9.44 0.45 5.78e-19 Type 2 diabetes; LIHC cis rs1878931 1.000 rs1878931 chr16:3450907 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.78 12.04 0.55 4.47e-28 Body mass index (adult); LIHC cis rs7249142 0.562 rs10854009 chr19:19284705 A/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.12 -0.31 2.6e-9 IgG glycosylation; LIHC cis rs7312933 0.966 rs7977365 chr12:42513127 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.49 7.08 0.36 8.47e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2153535 0.580 rs1932283 chr6:8477661 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.18 0.55 1.35e-28 Motion sickness; LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg10360139 chr7:1886902 MAD1L1 -0.41 -6.29 -0.32 9.65e-10 Bipolar disorder and schizophrenia; LIHC cis rs13161895 1.000 rs4235504 chr5:179453680 T/C cg02702477 chr5:179499311 RNF130 0.75 10.45 0.49 2.26e-22 LDL cholesterol; LIHC cis rs67478160 0.619 rs11628481 chr14:104241499 C/T cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.79 -0.39 8.12e-14 Schizophrenia; LIHC cis rs35110281 0.667 rs2070533 chr21:45122753 G/A cg04455712 chr21:45112962 RRP1B 0.49 8.58 0.42 3.43e-16 Mean corpuscular volume; LIHC cis rs10508774 1.000 rs117557786 chr10:32930076 A/G cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs13177918 0.626 rs2748240 chr5:149828868 A/G cg14059543 chr5:149831962 NA -0.47 -7.34 -0.37 1.54e-12 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs208520 0.690 rs3843513 chr6:66836797 A/G cg07460842 chr6:66804631 NA -0.79 -8.65 -0.42 1.96e-16 Exhaled nitric oxide output; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.23 0.55 8.65e-29 Prudent dietary pattern; LIHC cis rs5769765 0.955 rs4075330 chr22:50303249 G/A cg02269571 chr22:50332266 NA -0.65 -8.99 -0.44 1.69e-17 Schizophrenia; LIHC cis rs1113500 0.933 rs3893034 chr1:108632178 G/A cg06207961 chr1:108661230 NA 0.38 7.48 0.37 6.47e-13 Growth-regulated protein alpha levels; LIHC cis rs72781680 1.000 rs72781679 chr2:24237712 G/A cg08917208 chr2:24149416 ATAD2B 0.94 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC cis rs56104184 0.775 rs117016425 chr19:49400216 C/T cg21252483 chr19:49399788 TULP2 -1.06 -12.1 -0.55 2.64e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs614226 1.000 rs12310837 chr12:120880572 C/T cg01236616 chr12:121019343 POP5 1.04 11.22 0.52 4.54e-25 Type 1 diabetes nephropathy; LIHC cis rs2629540 0.847 rs34032724 chr10:126408869 T/G cg20435097 chr10:126320824 FAM53B -0.41 -6.0 -0.31 4.96e-9 Cocaine dependence; LIHC cis rs7116495 0.609 rs4945392 chr11:71694645 C/T cg10381502 chr11:71823885 C11orf51 -1.0 -8.24 -0.41 3.84e-15 Severe influenza A (H1N1) infection; LIHC trans rs1814175 0.587 rs7948538 chr11:50021353 A/C cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs67311347 1.000 rs951560 chr3:40463471 A/G cg09455208 chr3:40491958 NA 0.33 6.6 0.34 1.54e-10 Renal cell carcinoma; LIHC cis rs6582630 0.555 rs2387598 chr12:38510472 G/A cg26384229 chr12:38710491 ALG10B -0.66 -9.8 -0.47 3.79e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs9324022 0.790 rs7156824 chr14:101171480 C/A cg18089426 chr14:101175970 NA 0.48 5.83 0.3 1.26e-8 Plateletcrit; LIHC cis rs17253792 0.545 rs12893676 chr14:56016159 G/A cg01858014 chr14:56050164 KTN1 -0.62 -5.89 -0.3 9.46e-9 Putamen volume; LIHC cis rs11864453 0.826 rs2072142 chr16:72132713 C/T cg16558253 chr16:72132732 DHX38 -0.52 -8.15 -0.4 7.01e-15 Fibrinogen levels; LIHC cis rs11098499 0.908 rs28559989 chr4:120386627 C/T cg09307838 chr4:120376055 NA 0.77 11.98 0.54 7.27e-28 Corneal astigmatism; LIHC cis rs9596863 1.000 rs9591538 chr13:54407573 A/C ch.13.53330881F chr13:54432880 NA 0.44 6.0 0.31 4.99e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs67460515 0.563 rs6794882 chr3:160851849 G/A cg03342759 chr3:160939853 NMD3 -0.62 -9.1 -0.44 7.53e-18 Parkinson's disease; LIHC cis rs2075371 1.000 rs1862047 chr7:133978078 G/C cg11752832 chr7:134001865 SLC35B4 0.48 7.36 0.37 1.34e-12 Mean platelet volume; LIHC cis rs2386661 0.695 rs7093321 chr10:5662135 C/A cg17085576 chr10:5658249 NA -0.36 -6.44 -0.33 4.05e-10 Breast cancer; LIHC cis rs7945718 0.905 rs10831908 chr11:12812419 G/A cg25843174 chr11:12811716 TEAD1 0.38 8.77 0.43 8.53e-17 Educational attainment (years of education); LIHC cis rs765787 0.530 rs4775837 chr15:45537684 G/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs3770081 1.000 rs73947314 chr2:86273116 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.85 -9.04 -0.44 1.23e-17 Facial emotion recognition (sad faces); LIHC cis rs1577917 0.561 rs3087978 chr6:86388223 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.45 8.56 0.42 3.98e-16 Response to antipsychotic treatment; LIHC cis rs17094222 0.812 rs11190657 chr10:102442189 T/C cg26540559 chr10:102447443 NA 0.33 6.19 0.32 1.76e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs2073499 1.000 rs57319506 chr3:50285677 T/C cg21659725 chr3:3221576 CRBN 0.64 6.45 0.33 3.73e-10 Schizophrenia; LIHC cis rs9916302 0.904 rs35285898 chr17:37555872 A/C cg00129232 chr17:37814104 STARD3 0.4 6.33 0.32 7.78e-10 Glomerular filtration rate (creatinine); LIHC cis rs1577917 1.000 rs955196 chr6:86729951 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 5.9 0.3 8.79e-9 Response to antipsychotic treatment; LIHC cis rs10207060 0.771 rs4852124 chr2:240680022 C/T cg07506560 chr2:240697449 NA 0.51 8.83 0.43 5.73e-17 Obesity-related traits; LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.53 -0.33 2.42e-10 Total body bone mineral density; LIHC cis rs2637266 1.000 rs7098929 chr10:78361194 T/G cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.97e-9 Pulmonary function; LIHC cis rs921968 0.548 rs13427522 chr2:219438359 C/T cg02985541 chr2:219472218 PLCD4 0.44 8.39 0.41 1.28e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -6.05 -0.31 3.85e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2795502 1.000 rs2142991 chr10:43341105 C/T cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs6952808 0.594 rs3778969 chr7:2139990 A/G cg20295408 chr7:1910781 MAD1L1 0.4 5.79 0.3 1.59e-8 Bipolar disorder and schizophrenia; LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg07755735 chr2:20870362 GDF7 -0.45 -9.6 -0.46 1.77e-19 Abdominal aortic aneurysm; LIHC cis rs1018836 0.859 rs10808614 chr8:91569677 C/G cg16814680 chr8:91681699 NA -0.54 -8.46 -0.42 7.9e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1577917 0.771 rs2475790 chr6:86368068 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -8.04 -0.4 1.46e-14 Response to antipsychotic treatment; LIHC trans rs35110281 0.807 rs9976441 chr21:45046591 G/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.67 0.34 1.03e-10 Mean corpuscular volume; LIHC cis rs10832963 0.924 rs10832950 chr11:18635815 A/G cg20219074 chr11:18656078 SPTY2D1 0.84 13.95 0.6 2.57e-35 Breast cancer; LIHC cis rs2797685 1.000 rs2640908 chr1:7889941 C/T cg04725166 chr1:7887271 PER3 -0.41 -7.3 -0.37 2e-12 Crohn's disease; LIHC cis rs10911363 0.592 rs10797886 chr1:183479090 T/C cg09173681 chr1:183549694 NCF2 0.54 9.5 0.46 3.9e-19 Systemic lupus erythematosus; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg24335600 chr1:241682994 FH -0.41 -6.54 -0.33 2.3e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs3812831 0.669 rs382913 chr13:114928255 G/T cg08824895 chr13:115047677 UPF3A 0.48 6.96 0.35 1.74e-11 Schizophrenia; LIHC cis rs2153535 0.580 rs2143356 chr6:8517675 C/T cg21535247 chr6:8435926 SLC35B3 0.63 8.22 0.41 4.32e-15 Motion sickness; LIHC cis rs13064411 0.660 rs1872747 chr3:113175785 T/A cg18753928 chr3:113234510 CCDC52 -0.45 -6.32 -0.32 8.36e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -5.91 -0.3 8.23e-9 Diastolic blood pressure; LIHC trans rs11039798 0.614 rs2174703 chr11:48788242 G/A cg15704280 chr7:45808275 SEPT13 0.63 6.53 0.33 2.38e-10 Axial length; LIHC cis rs1355223 0.872 rs913204 chr11:34706224 C/G cg11058730 chr11:34937778 PDHX;APIP 0.41 5.98 0.31 5.7e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs11628318 0.853 rs28444760 chr14:103041148 A/G cg12046867 chr14:103022105 NA -0.57 -8.43 -0.41 9.98e-16 Platelet count; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg24209194 chr3:40518798 ZNF619 -0.63 -9.6 -0.46 1.81e-19 Renal cell carcinoma; LIHC cis rs7633770 0.710 rs34820891 chr3:46698059 A/G cg11219411 chr3:46661640 NA -0.41 -7.16 -0.36 5.06e-12 Coronary artery disease; LIHC cis rs3733585 0.783 rs13148371 chr4:10032561 C/T cg11266682 chr4:10021025 SLC2A9 0.35 7.45 0.37 7.56e-13 Cleft plate (environmental tobacco smoke interaction); LIHC cis rs10791097 0.694 rs2155751 chr11:130755240 G/A cg14779329 chr11:130786720 SNX19 0.4 6.03 0.31 4.35e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs61931739 0.500 rs7971957 chr12:34477558 C/T cg26384229 chr12:38710491 ALG10B 0.65 8.25 0.41 3.37e-15 Morning vs. evening chronotype; LIHC cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg18252515 chr7:66147081 NA -1.27 -16.34 -0.66 9.2e-45 Diabetic kidney disease; LIHC cis rs903552 1.000 rs12908079 chr15:102003820 C/A cg00659931 chr15:102010125 PCSK6 -0.45 -6.31 -0.32 8.74e-10 Diabetic kidney disease; LIHC cis rs25645 0.502 rs1563103 chr17:38111740 G/A cg17467752 chr17:38218738 THRA 0.4 5.81 0.3 1.42e-8 Myeloid white cell count; LIHC cis rs922107 0.846 rs424350 chr1:90006544 G/A cg15422784 chr1:90023713 LRRC8B -0.47 -7.37 -0.37 1.28e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs35110281 0.693 rs3819161 chr21:45092653 A/G cg21573476 chr21:45109991 RRP1B -0.63 -11.39 -0.52 1.06e-25 Mean corpuscular volume; LIHC cis rs3859192 0.577 rs25645 chr17:38173143 G/A cg10374813 chr17:38183790 MED24;SNORD124 -0.31 -5.71 -0.3 2.41e-8 White blood cell count; LIHC cis rs7552404 0.961 rs17587071 chr1:76225083 A/C cg22875332 chr1:76189707 ACADM 0.48 6.89 0.35 2.7e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg14893161 chr1:205819251 PM20D1 0.71 10.33 0.49 5.95e-22 Menarche (age at onset); LIHC cis rs9816226 0.591 rs57912727 chr3:185804583 A/C cg00760338 chr3:185826511 ETV5 -0.71 -6.0 -0.31 5.07e-9 Obesity;Body mass index; LIHC cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg18252515 chr7:66147081 NA -1.26 -17.06 -0.68 1.18e-47 Diabetic kidney disease; LIHC cis rs2274273 0.967 rs11622740 chr14:55617844 G/A cg01864836 chr14:55583639 NA -0.36 -6.12 -0.31 2.62e-9 Protein biomarker; LIHC cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg25894440 chr7:65020034 NA 0.56 6.39 0.33 5.55e-10 Diabetic kidney disease; LIHC cis rs4332037 0.539 rs34571717 chr7:2106855 T/C cg23422044 chr7:1970798 MAD1L1 -0.55 -8.53 -0.42 4.81e-16 Bipolar disorder; LIHC cis rs10911232 0.507 rs10911222 chr1:183047363 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.6 0.5 6.65e-23 Hypertriglyceridemia; LIHC cis rs3741404 0.609 rs641378 chr11:63869493 T/C cg05016508 chr11:63871570 FLRT1;MACROD1 0.41 6.58 0.34 1.78e-10 Platelet count; LIHC cis rs11031096 0.678 rs970329 chr11:4189803 G/T cg18678763 chr11:4115507 RRM1 -0.41 -5.95 -0.31 6.62e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1799949 0.683 rs55737636 chr17:41264739 C/T cg05368731 chr17:41323189 NBR1 0.69 11.4 0.52 9.71e-26 Menopause (age at onset); LIHC cis rs2204008 0.653 rs11182569 chr12:38572452 G/A cg26384229 chr12:38710491 ALG10B 0.97 12.66 0.56 2.12e-30 Bladder cancer; LIHC cis rs1403694 0.695 rs1836860 chr3:186436604 C/T cg12454167 chr3:186435060 KNG1 -0.37 -8.6 -0.42 2.88e-16 Blood protein levels; LIHC cis rs2016586 0.719 rs5999971 chr22:36115349 C/T cg26342177 chr22:36113512 APOL5 -0.39 -6.55 -0.33 2.13e-10 Body mass index; LIHC cis rs10089 1.000 rs4835943 chr5:127457569 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.05e-11 Ileal carcinoids; LIHC cis rs4319547 0.695 rs10773103 chr12:122856532 A/G cg05707623 chr12:122985044 ZCCHC8 0.54 7.18 0.36 4.46e-12 Body mass index; LIHC trans rs7142002 1.000 rs59070929 chr14:102361737 G/A cg18984499 chr17:8286166 RPL26 0.65 6.19 0.32 1.77e-9 Autism; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00014996 chr18:158348 USP14 0.41 6.25 0.32 1.23e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7408868 1.000 rs757475 chr19:15273749 C/T cg09752223 chr19:15281200 NOTCH3 -0.37 -5.78 -0.3 1.65e-8 Pulse pressure; LIHC cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg18230493 chr5:56204884 C5orf35 -0.47 -6.61 -0.34 1.5e-10 Initial pursuit acceleration; LIHC cis rs600231 0.706 rs10896016 chr11:65335705 C/T cg13974409 chr11:65292307 SCYL1 -0.37 -6.01 -0.31 4.77e-9 Bone mineral density; LIHC cis rs12220238 0.908 rs11000893 chr10:75905996 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.58 0.34 1.78e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1707322 0.721 rs10890337 chr1:46124527 C/T cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6088590 0.550 rs12624640 chr20:32952125 G/A cg06115741 chr20:33292138 TP53INP2 0.53 7.29 0.37 2.16e-12 Coronary artery disease; LIHC cis rs5769765 0.913 rs8135071 chr22:50299587 T/C cg02269571 chr22:50332266 NA -0.61 -8.69 -0.43 1.54e-16 Schizophrenia; LIHC cis rs7027203 1.000 rs34624092 chr9:96523092 G/A cg14598338 chr9:96623480 NA 0.31 5.97 0.31 5.98e-9 DNA methylation (variation); LIHC cis rs600806 0.742 rs9429519 chr1:110017105 A/G cg23091122 chr1:110024289 SYPL2 0.42 5.77 0.3 1.8e-8 Intelligence (multi-trait analysis); LIHC cis rs8067354 0.574 rs9789060 chr17:58018570 A/G cg02344993 chr17:57696989 CLTC 0.65 10.29 0.49 8.48e-22 Hemoglobin concentration; LIHC cis rs7216064 1.000 rs56393562 chr17:65933918 C/T cg12091567 chr17:66097778 LOC651250 -0.61 -8.62 -0.42 2.61e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs11098499 0.954 rs17009122 chr4:120362403 G/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs4820539 0.966 rs2267001 chr22:23456696 T/C cg14186256 chr22:23484241 RTDR1 0.91 18.37 0.7 6.1e-53 Bone mineral density; LIHC cis rs17685 0.725 rs2302436 chr7:75676988 A/T cg16684958 chr7:75615977 POR -0.5 -8.27 -0.41 2.91e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs561341 1.000 rs56362439 chr17:30253140 T/A cg13647721 chr17:30228624 UTP6 0.71 6.76 0.34 6.02e-11 Hip circumference adjusted for BMI; LIHC cis rs2153535 0.580 rs9378554 chr6:8488468 C/T cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC trans rs12310956 0.532 rs1525897 chr12:33941033 C/T cg26384229 chr12:38710491 ALG10B 0.5 6.86 0.35 3.19e-11 Morning vs. evening chronotype; LIHC cis rs2637266 0.783 rs860165 chr10:78492807 A/G cg18941641 chr10:78392320 NA 0.27 5.81 0.3 1.44e-8 Pulmonary function; LIHC cis rs1005277 0.579 rs1780121 chr10:38529437 C/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.54 -0.46 2.77e-19 Extrinsic epigenetic age acceleration; LIHC cis rs72627123 0.867 rs11848920 chr14:74476866 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.75 0.47 5.75e-20 Morning vs. evening chronotype; LIHC cis rs3091242 0.933 rs28530483 chr1:25740847 A/C cg09222892 chr1:25734099 RHCE -0.45 -8.38 -0.41 1.43e-15 Erythrocyte sedimentation rate; LIHC cis rs60871478 0.898 rs4720929 chr7:808009 T/C cg05535760 chr7:792225 HEATR2 0.8 11.29 0.52 2.46e-25 Cerebrospinal P-tau181p levels; LIHC cis rs17106184 0.551 rs35166191 chr1:50843153 C/T cg07174182 chr1:51127561 FAF1 -0.44 -5.89 -0.3 9.22e-9 Type 2 diabetes; LIHC cis rs10927875 0.562 rs10803401 chr1:16147377 G/A cg21385522 chr1:16154831 NA -1.06 -17.37 -0.68 7.03e-49 Dilated cardiomyopathy; LIHC cis rs11190604 1.000 rs11190570 chr10:102227702 G/C cg07080220 chr10:102295463 HIF1AN 0.5 7.03 0.36 1.12e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9381040 0.599 rs2057001 chr6:41022947 A/G cg03644281 chr6:41068752 NFYA;LOC221442 -0.4 -5.77 -0.3 1.82e-8 Alzheimer's disease (late onset); LIHC cis rs6701037 0.681 rs1057239 chr1:175130204 G/A cg00321850 chr1:175162397 KIAA0040 -0.43 -6.81 -0.35 4.42e-11 Alcohol dependence; LIHC trans rs1499614 1.000 rs2707838 chr7:66159201 C/T cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs4631830 0.896 rs7088225 chr10:51522120 T/C cg20129853 chr10:51489980 NA 0.42 9.15 0.44 5.11e-18 Prostate-specific antigen levels; LIHC trans rs637571 0.546 rs11227311 chr11:65585257 C/A cg17712092 chr4:129076599 LARP1B -0.69 -10.51 -0.49 1.46e-22 Eosinophil percentage of white cells; LIHC trans rs1864585 0.520 rs17720365 chr8:10679499 C/G cg26278703 chr11:58910052 FAM111A -0.68 -6.71 -0.34 8.04e-11 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs8062405 0.690 rs7187604 chr16:28565953 A/G cg07451762 chr16:28383216 NA 0.4 7.24 0.36 3e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7572733 0.534 rs6434943 chr2:198762192 T/G cg10820045 chr2:198174542 NA 0.48 7.27 0.37 2.45e-12 Dermatomyositis; LIHC cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg03721293 chr16:90014378 DEF8 0.42 7.0 0.35 1.33e-11 Skin colour saturation; LIHC cis rs6840360 0.615 rs6535822 chr4:152679722 A/G cg22705602 chr4:152727874 NA -0.4 -8.34 -0.41 1.88e-15 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12954385 chr21:46686990 POFUT2 0.37 6.29 0.32 9.6e-10 Longevity; LIHC cis rs1801251 1.000 rs6761324 chr2:233582793 T/G cg08000102 chr2:233561755 GIGYF2 0.75 11.29 0.52 2.54e-25 Coronary artery disease; LIHC cis rs9612 0.718 rs346532 chr19:44248878 A/G cg08581076 chr19:44259116 C19orf61 0.59 7.73 0.39 1.23e-13 Exhaled nitric oxide output; LIHC cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg09025071 chr16:1593152 IFT140;TMEM204 0.33 6.62 0.34 1.36e-10 Coronary artery disease; LIHC cis rs9309711 0.666 rs6723126 chr2:3484500 T/C cg10845886 chr2:3471009 TTC15 -0.44 -8.34 -0.41 1.87e-15 Neurofibrillary tangles; LIHC cis rs597539 0.616 rs631001 chr11:68642974 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.41 0.49 3.2e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs4332037 0.523 rs11770148 chr7:1899447 A/G cg23422044 chr7:1970798 MAD1L1 -0.64 -6.85 -0.35 3.5e-11 Bipolar disorder; LIHC cis rs4808199 0.947 rs751858 chr19:19602821 G/C cg20644253 chr19:19431407 KIAA0892;SF4 0.41 5.9 0.3 8.86e-9 Nonalcoholic fatty liver disease; LIHC cis rs1801251 1.000 rs283484 chr2:233646505 A/G cg08000102 chr2:233561755 GIGYF2 0.77 11.58 0.53 2.22e-26 Coronary artery disease; LIHC cis rs11098699 0.821 rs6830258 chr4:124230345 A/G cg09941581 chr4:124220074 SPATA5 -0.33 -6.54 -0.33 2.2e-10 Mosquito bite size; LIHC cis rs17253792 0.732 rs79014965 chr14:56117551 T/G cg01858014 chr14:56050164 KTN1 -0.71 -7.22 -0.36 3.38e-12 Putamen volume; LIHC cis rs12497850 1.000 rs12497850 chr3:48748989 G/T cg07636037 chr3:49044803 WDR6 0.81 13.85 0.6 6.16e-35 Parkinson's disease; LIHC cis rs1419980 0.630 rs2377089 chr12:7737325 T/C cg14906510 chr12:7781169 NA 0.44 6.81 0.35 4.42e-11 HDL cholesterol levels; LIHC cis rs6952808 0.931 rs7810038 chr7:1894116 T/C cg14004847 chr7:1930337 MAD1L1 -0.44 -6.19 -0.32 1.76e-9 Bipolar disorder and schizophrenia; LIHC cis rs2404602 0.684 rs57682236 chr15:76868478 G/A cg03037974 chr15:76606532 NA -0.6 -9.94 -0.47 1.25e-20 Blood metabolite levels; LIHC cis rs7395581 0.918 rs3847502 chr11:47333685 C/A cg25783544 chr11:47291846 MADD 0.41 5.95 0.31 6.8e-9 HDL cholesterol; LIHC cis rs9902453 0.967 rs6505155 chr17:28372783 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.86 -0.54 2.14e-27 Coffee consumption (cups per day); LIHC cis rs10791097 0.568 rs4411284 chr11:130738568 A/C cg09137382 chr11:130731461 NA 0.4 6.04 0.31 3.92e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs597539 0.652 rs557625 chr11:68634722 G/A cg06028808 chr11:68637592 NA 0.43 5.85 0.3 1.16e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs4407350 0.756 rs131168 chr22:44896225 T/C cg04154583 chr22:44889756 LDOC1L 0.29 5.88 0.3 9.97e-9 Intelligence (multi-trait analysis); LIHC cis rs2070488 1.000 rs7433707 chr3:38443180 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.68 0.65 4.03e-42 Electrocardiographic conduction measures; LIHC cis rs12744310 0.887 rs12046670 chr1:41809312 T/G cg03387723 chr1:41708464 SCMH1 -0.32 -5.86 -0.3 1.12e-8 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg04632378 chr13:21900426 NA 0.4 6.79 0.34 4.93e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs903552 0.935 rs8041582 chr15:102005851 G/A cg00659931 chr15:102010125 PCSK6 -0.46 -6.2 -0.32 1.63e-9 Diabetic kidney disease; LIHC cis rs11122272 0.735 rs2250734 chr1:231485958 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.2 -0.52 5.02e-25 Hemoglobin concentration; LIHC cis rs870825 0.929 rs72689269 chr4:185592085 T/C cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs2732480 0.577 rs2634678 chr12:48735538 C/G cg21466736 chr12:48725269 NA -0.73 -11.1 -0.51 1.15e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs11711311 1.000 rs9851731 chr3:113502651 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.36 6.64 0.34 1.23e-10 IgG glycosylation; LIHC cis rs57502260 1.000 rs56312530 chr11:68219415 G/A cg16797656 chr11:68205561 LRP5 0.59 8.03 0.4 1.57e-14 Total body bone mineral density (age 45-60); LIHC cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.93 9.58 0.46 2.1e-19 Platelet count; LIHC trans rs877282 0.898 rs11253352 chr10:766598 C/A cg22713356 chr15:30763199 NA 1.4 12.21 0.55 1.06e-28 Uric acid levels; LIHC cis rs9596863 0.898 rs9568920 chr13:54352810 A/T ch.13.53330881F chr13:54432880 NA 0.45 6.04 0.31 3.93e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs11190604 1.000 rs17113137 chr10:102241998 G/C cg07080220 chr10:102295463 HIF1AN 0.51 7.13 0.36 6.07e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs4908768 0.657 rs3938719 chr1:8804997 A/G cg20416874 chr1:8611966 RERE 0.42 6.15 0.32 2.19e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs35110281 0.693 rs2838344 chr21:45089877 C/T cg21573476 chr21:45109991 RRP1B -0.57 -10.93 -0.51 4.66e-24 Mean corpuscular volume; LIHC cis rs12188164 0.525 rs1114665 chr5:452247 C/T cg24955955 chr5:415729 AHRR 0.32 6.32 0.32 8.14e-10 Cystic fibrosis severity; LIHC cis rs4888262 0.526 rs7193508 chr16:74628630 G/T cg01733217 chr16:74700730 RFWD3 0.83 16.18 0.66 3.82e-44 Testicular germ cell tumor; LIHC cis rs10464366 0.746 rs6945547 chr7:39145389 C/G cg15212455 chr7:39170539 POU6F2 0.43 7.81 0.39 7.2e-14 IgG glycosylation; LIHC cis rs9888615 1.000 rs12887631 chr14:53373399 A/T cg00686598 chr14:53173677 PSMC6 -0.5 -6.14 -0.32 2.23e-9 Systolic blood pressure; LIHC cis rs1997103 1.000 rs10263552 chr7:55404747 C/T cg17469321 chr7:55412551 NA 0.48 7.01 0.35 1.32e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs4727027 0.704 rs13221837 chr7:148903597 C/T cg23583168 chr7:148888333 NA -0.76 -11.76 -0.54 4.89e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs868036 0.718 rs8025790 chr15:68076399 G/T cg24579218 chr15:68104479 NA -0.34 -5.83 -0.3 1.27e-8 Restless legs syndrome; LIHC cis rs3749237 0.595 rs11720264 chr3:49580347 C/T cg02487422 chr3:49467188 NICN1 0.39 5.94 0.31 6.88e-9 Resting heart rate; LIHC cis rs8141529 0.748 rs5762881 chr22:29289346 C/A cg02153584 chr22:29168773 CCDC117 0.51 7.97 0.4 2.36e-14 Lymphocyte counts; LIHC cis rs10870270 1.000 rs10781564 chr10:133757922 A/G cg26149184 chr10:133730230 NA 0.46 7.24 0.36 2.97e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg00061764 chr3:67564432 SUCLG2 0.38 6.25 0.32 1.24e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs4845459 0.967 rs477392 chr1:152555176 C/G cg20634798 chr1:152595351 LCE3A -0.29 -5.95 -0.31 6.64e-9 Psoriasis; LIHC cis rs1775715 0.737 rs2799031 chr10:32173168 C/T cg14930904 chr10:32216787 ARHGAP12 0.35 6.16 0.32 2.02e-9 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs1005277 0.505 rs7069702 chr10:38247359 G/T cg27523141 chr10:43048294 ZNF37B -0.39 -6.79 -0.34 4.84e-11 Extrinsic epigenetic age acceleration; LIHC cis rs10097731 0.901 rs10464890 chr8:82042727 A/G cg25230327 chr8:82042993 NA -0.59 -8.01 -0.4 1.81e-14 Serum total protein level; LIHC cis rs68170813 0.559 rs2107318 chr7:106845969 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg18252515 chr7:66147081 NA 1.27 16.79 0.67 1.38e-46 Diabetic kidney disease; LIHC cis rs240764 0.853 rs11155496 chr6:100988939 T/C cg09795085 chr6:101329169 ASCC3 -0.43 -5.87 -0.3 1.04e-8 Neuroticism; LIHC cis rs12586317 0.547 rs77262907 chr14:35495734 C/G cg05294307 chr14:35346193 BAZ1A -0.5 -7.52 -0.38 4.91e-13 Psoriasis; LIHC cis rs611744 0.901 rs2348801 chr8:109167337 C/T cg21045802 chr8:109455806 TTC35 0.5 8.61 0.42 2.65e-16 Dupuytren's disease; LIHC cis rs332507 0.789 rs10755078 chr3:124378412 A/G cg05980111 chr3:124395277 KALRN 0.46 7.06 0.36 9.47e-12 Plateletcrit; LIHC cis rs12744310 1.000 rs12723893 chr1:41757040 C/T cg03962019 chr1:41807865 NA 0.38 6.1 0.31 2.82e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7264396 0.733 rs6058305 chr20:34310757 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.69 -11.98 -0.54 7.21e-28 Total cholesterol levels; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg13152130 chr6:118910203 C6orf204 -0.65 -7.47 -0.37 6.87e-13 Diastolic blood pressure; LIHC cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.31 0.45 1.56e-18 Electroencephalogram traits; LIHC cis rs35110281 1.000 rs35110281 chr21:45068947 T/A cg01579765 chr21:45077557 HSF2BP -0.35 -6.49 -0.33 3e-10 Mean corpuscular volume; LIHC cis rs9297145 0.585 rs4729521 chr7:98780520 G/T cg05967295 chr7:98741636 SMURF1 -0.39 -6.53 -0.33 2.35e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs853679 0.517 rs9368555 chr6:28108967 T/C cg16479474 chr6:28041457 NA 0.45 6.34 0.32 7.43e-10 Depression; LIHC cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.82 -9.81 -0.47 3.56e-20 Mean platelet volume; LIHC cis rs3018712 0.532 rs4930588 chr11:68415235 A/C cg16797656 chr11:68205561 LRP5 0.45 5.88 0.3 9.65e-9 Total body bone mineral density; LIHC cis rs7116495 1.000 rs2298457 chr11:71734211 T/C cg26138937 chr11:71823887 C11orf51 -0.83 -8.45 -0.42 8.57e-16 Severe influenza A (H1N1) infection; LIHC cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg18306943 chr3:40428807 ENTPD3 0.41 7.11 0.36 6.86e-12 Renal cell carcinoma; LIHC cis rs11122272 0.735 rs2790892 chr1:231512771 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.69 -0.5 3.38e-23 Hemoglobin concentration; LIHC cis rs10508774 1.000 rs35574674 chr10:32816382 C/T cg01819863 chr10:32635814 EPC1 0.65 5.95 0.31 6.75e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg05296608 chr10:134537282 INPP5A 0.42 6.04 0.31 4.04e-9 Bilirubin levels; LIHC trans rs7395662 0.611 rs4882089 chr11:48515612 A/T cg15704280 chr7:45808275 SEPT13 -0.45 -6.81 -0.35 4.52e-11 HDL cholesterol; LIHC cis rs34779708 0.966 rs35814343 chr10:35427714 G/T cg04310649 chr10:35416472 CREM -0.43 -5.84 -0.3 1.19e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2050392 0.965 rs2265370 chr10:30690581 C/T cg25182066 chr10:30743637 MAP3K8 -0.45 -7.23 -0.36 3.22e-12 Inflammatory bowel disease; LIHC cis rs7666738 0.546 rs62320963 chr4:98839297 A/G cg05340658 chr4:99064831 C4orf37 0.5 6.58 0.34 1.82e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs9325144 0.647 rs61931899 chr12:38892422 A/G cg26384229 chr12:38710491 ALG10B -0.56 -7.59 -0.38 3.11e-13 Morning vs. evening chronotype; LIHC cis rs7520050 0.933 rs9787208 chr1:46314616 C/A cg03146154 chr1:46216737 IPP -0.37 -5.92 -0.3 8e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2153535 0.601 rs4140585 chr6:8503298 T/A cg23788917 chr6:8435910 SLC35B3 0.59 8.37 0.41 1.51e-15 Motion sickness; LIHC cis rs10504229 0.679 rs12675340 chr8:58035501 T/A cg08219700 chr8:58056026 NA 0.38 5.78 0.3 1.64e-8 Developmental language disorder (linguistic errors); LIHC cis rs25645 0.502 rs7209742 chr17:38108708 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.47 -7.06 -0.36 9.28e-12 Myeloid white cell count; LIHC cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.04 10.51 0.49 1.43e-22 Platelet count; LIHC trans rs6951245 0.744 rs10265736 chr7:1172465 C/T cg13565492 chr6:43139072 SRF -0.75 -6.14 -0.32 2.3e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 12.34 0.55 3.52e-29 Alzheimer's disease; LIHC cis rs2228479 0.850 rs2238527 chr16:89840708 C/A cg19635926 chr16:89946313 TCF25 0.5 6.48 0.33 3.24e-10 Skin colour saturation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05975845 chr20:47538463 ARFGEF2 0.46 6.04 0.31 4.08e-9 Lung function (FEV1/FVC); LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.81 -0.35 4.43e-11 Total body bone mineral density; LIHC cis rs2239547 0.522 rs9844736 chr3:52931971 T/G cg11645453 chr3:52864694 ITIH4 -0.31 -7.67 -0.38 1.79e-13 Schizophrenia; LIHC cis rs910316 0.763 rs175042 chr14:75470833 A/T cg08847533 chr14:75593920 NEK9 -0.86 -17.21 -0.68 2.94e-48 Height; LIHC cis rs1008375 0.898 rs4698623 chr4:17594702 T/C cg02297831 chr4:17616191 MED28 0.46 7.08 0.36 7.99e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs918629 0.798 rs6556894 chr5:95289542 G/A cg10483112 chr5:95245456 ELL2 -0.37 -6.44 -0.33 4.02e-10 IgG glycosylation; LIHC cis rs208520 1.000 rs12192261 chr6:66985268 A/G cg07460842 chr6:66804631 NA 0.67 7.29 0.37 2.24e-12 Exhaled nitric oxide output; LIHC cis rs1707322 0.686 rs1547924 chr1:46085112 C/T cg24296786 chr1:45957014 TESK2 -0.44 -6.35 -0.32 6.73e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs986417 0.748 rs4901986 chr14:60969333 T/C cg27398547 chr14:60952738 C14orf39 0.75 9.04 0.44 1.2e-17 Gut microbiota (bacterial taxa); LIHC trans rs72829446 0.530 rs7222404 chr17:7384198 G/A cg08566640 chr11:64091735 NA -0.67 -6.13 -0.31 2.36e-9 Androgen levels; LIHC cis rs2274273 0.840 rs28568813 chr14:55794114 C/G cg01864836 chr14:55583639 NA -0.4 -7.46 -0.37 7.2e-13 Protein biomarker; LIHC cis rs644799 0.965 rs3789960 chr11:95509037 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.7 0.46 7.98e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7534824 0.625 rs58234233 chr1:101510440 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.68 7.59 0.38 2.98e-13 Refractive astigmatism; LIHC cis rs826838 0.678 rs11182781 chr12:38610178 C/T cg26384229 chr12:38710491 ALG10B 0.97 12.66 0.56 2.12e-30 Heart rate; LIHC cis rs2845885 0.744 rs3802932 chr11:63988045 G/A cg18375707 chr11:64034959 PLCB3 -0.68 -9.75 -0.47 5.78e-20 Body mass index; LIHC cis rs6714710 0.603 rs6757357 chr2:98491750 T/C cg26665480 chr2:98280029 ACTR1B 0.44 6.2 0.32 1.67e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs35883536 0.566 rs10783141 chr1:101043897 G/A cg14515779 chr1:101123966 NA 0.47 6.73 0.34 7.27e-11 Monocyte count; LIHC cis rs7647973 1.000 rs62261249 chr3:49594060 T/C cg07636037 chr3:49044803 WDR6 -0.53 -6.41 -0.33 4.78e-10 Menarche (age at onset); LIHC trans rs2739330 0.685 rs4822453 chr22:24254862 G/T cg06437703 chr8:37914619 EIF4EBP1 -0.53 -7.91 -0.39 3.51e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11626933 1.000 rs3742669 chr14:90767746 C/A cg14092571 chr14:90743983 NA 0.9 14.94 0.63 3.5e-39 Gut microbiota (bacterial taxa); LIHC cis rs11212737 0.818 rs2624136 chr11:108513720 A/G cg22776369 chr11:108536276 DDX10 0.37 6.19 0.32 1.69e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs4803468 1.000 rs4803465 chr19:41918158 A/G cg09537434 chr19:41945824 ATP5SL 1.02 21.31 0.76 1.01e-64 Height; LIHC cis rs2439831 0.867 rs3809481 chr15:43662829 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.76 9.31 0.45 1.65e-18 Lung cancer in ever smokers; LIHC cis rs769267 0.895 rs2965182 chr19:19548246 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.02 0.31 4.53e-9 Tonsillectomy; LIHC cis rs34234989 1 rs34234989 chr20:33774533 CA/C cg08999081 chr20:33150536 PIGU 0.39 5.71 0.3 2.42e-8 Thrombosis; LIHC cis rs6448317 0.954 rs12186333 chr4:24919774 T/C cg21108841 chr4:24914750 CCDC149 -0.5 -6.32 -0.32 8.24e-10 Heschl's gyrus morphology; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg18000306 chr6:288505 NA 0.34 6.19 0.32 1.73e-9 Menopause (age at onset); LIHC cis rs4975709 0.589 rs931508 chr5:1861224 C/G cg14773178 chr5:1868261 NA 0.25 6.81 0.35 4.29e-11 Cardiovascular disease risk factors; LIHC cis rs6545883 0.868 rs6752938 chr2:61841588 C/T cg14146966 chr2:61757674 XPO1 0.45 7.9 0.39 3.94e-14 Tuberculosis; LIHC cis rs2576037 0.583 rs541634 chr18:44420271 C/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.08 -0.36 8.41e-12 Personality dimensions; LIHC cis rs6665290 0.935 rs6670924 chr1:227196048 A/C cg10327440 chr1:227177885 CDC42BPA -1.18 -25.93 -0.81 1e-82 Myeloid white cell count; LIHC cis rs921968 0.612 rs496908 chr2:219357742 A/T cg17980119 chr2:219472607 PLCD4 0.35 5.98 0.31 5.7e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs459571 1.000 rs459571 chr9:136912626 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.57 -8.57 -0.42 3.53e-16 Platelet distribution width; LIHC cis rs748404 0.646 rs2253268 chr15:43800968 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.54 0.38 4.39e-13 Lung cancer; LIHC cis rs477692 0.699 rs576175 chr10:131386408 A/T cg05714579 chr10:131428358 MGMT 0.43 7.06 0.36 9.38e-12 Response to temozolomide; LIHC cis rs9399135 0.816 rs4134030 chr6:135354094 G/T cg24558204 chr6:135376177 HBS1L 0.41 6.83 0.35 4.01e-11 Red blood cell count; LIHC cis rs10493773 0.609 rs12097932 chr1:86182216 A/G cg17807903 chr1:86174739 ZNHIT6 -0.61 -11.91 -0.54 1.33e-27 Urate levels in overweight individuals; LIHC cis rs7917772 0.507 rs2778036 chr10:104485725 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.58 6.67 0.34 1.04e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11048434 0.736 rs11048345 chr12:9123056 T/G cg04155231 chr12:9217510 LOC144571 0.31 5.86 0.3 1.1e-8 Sjögren's syndrome; LIHC trans rs1814175 0.588 rs10839463 chr11:49971643 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC cis rs9388451 0.626 rs1343115 chr6:126069817 C/G cg05901451 chr6:126070800 HEY2 -0.69 -14.61 -0.62 6.62e-38 Brugada syndrome; LIHC cis rs1707322 1.000 rs785478 chr1:46491635 C/T cg06784218 chr1:46089804 CCDC17 -0.36 -6.57 -0.33 1.9e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg13877915 chr19:58951672 ZNF132 0.63 10.57 0.5 8.54e-23 Uric acid clearance; LIHC cis rs769267 0.930 rs2301784 chr19:19390749 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs7520050 0.966 rs12139630 chr1:46350935 A/G cg03146154 chr1:46216737 IPP -0.39 -6.45 -0.33 3.78e-10 Red blood cell count;Reticulocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01519350 chr3:137906342 ARMC8 0.48 6.94 0.35 1.95e-11 Pancreatic cancer; LIHC cis rs12701220 0.655 rs6463317 chr7:1159243 G/A cg00990874 chr7:1149470 C7orf50 -0.67 -9.8 -0.47 3.94e-20 Bronchopulmonary dysplasia; LIHC cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs4716602 0.596 rs13221649 chr7:156160793 G/A cg16983916 chr7:156159713 NA -0.32 -5.71 -0.3 2.43e-8 Anti-saccade response; LIHC cis rs11671005 0.610 rs3794966 chr19:59068996 C/T cg25952890 chr19:58913133 NA 0.68 6.92 0.35 2.18e-11 Mean platelet volume; LIHC cis rs7940866 0.809 rs11222410 chr11:130833994 A/G cg12179176 chr11:130786555 SNX19 0.53 7.7 0.38 1.47e-13 Schizophrenia; LIHC cis rs798554 0.679 rs2533870 chr7:2885274 C/G cg13628971 chr7:2884303 GNA12 -0.57 -9.86 -0.47 2.41e-20 Height; LIHC cis rs1865721 1.000 rs7236756 chr18:73175689 T/C cg26385618 chr18:73139727 C18orf62 -0.3 -7.48 -0.38 6.12e-13 Intelligence; LIHC cis rs8103278 0.507 rs16939 chr19:46276056 C/A cg14061069 chr19:46274453 DMPK 0.71 13.42 0.59 2.76e-33 Coronary artery disease; LIHC cis rs11931598 0.511 rs4689576 chr4:7025523 T/C cg19539972 chr4:7069911 GRPEL1 0.4 6.26 0.32 1.15e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC trans rs72960926 0.744 rs72950563 chr6:74912043 G/C cg07247405 chr1:2484626 LOC115110 0.53 6.13 0.31 2.4e-9 Metabolite levels (MHPG); LIHC cis rs992157 0.560 rs7578940 chr2:219083318 G/T cg00012203 chr2:219082015 ARPC2 -0.88 -15.34 -0.64 8.84e-41 Colorectal cancer; LIHC cis rs9393777 0.588 rs6933213 chr6:26493909 T/C cg12826209 chr6:26865740 GUSBL1 0.63 7.64 0.38 2.19e-13 Intelligence (multi-trait analysis); LIHC cis rs7959452 0.527 rs4761157 chr12:69780907 A/G cg14784868 chr12:69753453 YEATS4 0.94 20.44 0.74 3.16e-61 Blood protein levels; LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs2346177 0.542 rs1900591 chr2:46697968 C/T cg02822958 chr2:46747628 ATP6V1E2 0.51 7.68 0.38 1.64e-13 HDL cholesterol; LIHC cis rs7945718 0.967 rs11022490 chr11:12773526 C/G cg25843174 chr11:12811716 TEAD1 -0.35 -8.07 -0.4 1.22e-14 Educational attainment (years of education); LIHC cis rs7208859 0.623 rs216434 chr17:28922335 G/C cg14067834 chr17:29058358 SUZ12P 0.68 6.66 0.34 1.12e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2204008 0.744 rs8189486 chr12:38244968 C/T cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.56e-8 Bladder cancer; LIHC cis rs7818382 1.000 rs7818382 chr8:96054000 C/T cg23172400 chr8:95962367 TP53INP1 -0.29 -6.36 -0.33 6.35e-10 Alzheimer's disease (late onset); LIHC cis rs2404602 1.000 rs12594541 chr15:76834368 G/A cg23625390 chr15:77176239 SCAPER 0.4 6.74 0.34 6.57e-11 Blood metabolite levels; LIHC cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.83 0.3 1.26e-8 Schizophrenia; LIHC cis rs7089973 0.646 rs35453961 chr10:116638166 T/C cg03647239 chr10:116582469 FAM160B1 0.47 6.86 0.35 3.3e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03442064 chr6:41515050 FOXP4 0.41 6.87 0.35 3.03e-11 Cognitive function; LIHC trans rs911555 0.755 rs8016676 chr14:103904842 C/A cg17675199 chr6:35436792 RPL10A -0.44 -9.14 -0.44 5.82e-18 Intelligence (multi-trait analysis); LIHC cis rs2760061 0.583 rs708123 chr1:228220495 A/G cg02753203 chr1:228287806 NA 0.83 14.96 0.63 2.69e-39 Diastolic blood pressure; LIHC cis rs11608355 0.515 rs7976796 chr12:109928013 C/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs2204008 0.536 rs12368354 chr12:38042798 G/A cg13010199 chr12:38710504 ALG10B 0.49 5.75 0.3 1.99e-8 Bladder cancer; LIHC cis rs7312933 0.703 rs2406567 chr12:42551479 G/C cg01256987 chr12:42539512 GXYLT1 -0.42 -7.1 -0.36 7.16e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4474465 0.688 rs10793336 chr11:78281867 A/G cg02023728 chr11:77925099 USP35 -0.34 -5.86 -0.3 1.09e-8 Alzheimer's disease (survival time); LIHC cis rs6456156 0.586 rs9459853 chr6:167465774 C/A cg23791538 chr6:167370224 RNASET2 -0.61 -10.49 -0.49 1.61e-22 Primary biliary cholangitis; LIHC cis rs703842 1.000 rs10431505 chr12:58178589 A/G cg18357645 chr12:58087776 OS9 -0.44 -7.03 -0.36 1.12e-11 Multiple sclerosis; LIHC cis rs17094222 0.853 rs10883521 chr10:102439754 A/T cg26540559 chr10:102447443 NA 0.32 6.0 0.31 5.05e-9 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.25 0.32 1.25e-9 Bipolar disorder; LIHC cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg25072359 chr17:41440525 NA 0.38 6.03 0.31 4.34e-9 Menopause (age at onset); LIHC cis rs12744310 1.000 rs12038894 chr1:41760207 C/T cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.72e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg13409248 chr3:40428643 ENTPD3 0.5 8.43 0.41 9.5e-16 Renal cell carcinoma; LIHC cis rs1005277 0.579 rs1614236 chr10:38502996 C/T cg25427524 chr10:38739819 LOC399744 -0.72 -14.01 -0.6 1.45e-35 Extrinsic epigenetic age acceleration; LIHC cis rs28735056 1.000 rs28735056 chr18:77622879 A/G cg20368463 chr18:77673604 PQLC1 -0.35 -6.36 -0.33 6.36e-10 Schizophrenia; LIHC cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -9.87 -0.47 2.23e-20 Platelet count; LIHC cis rs2839186 0.605 rs2839170 chr21:47671305 A/G cg12379764 chr21:47803548 PCNT -0.55 -7.9 -0.39 3.9e-14 Testicular germ cell tumor; LIHC cis rs7959452 0.590 rs11177619 chr12:69758871 G/A cg20891283 chr12:69753455 YEATS4 0.9 19.48 0.73 2.13e-57 Blood protein levels; LIHC cis rs8044995 0.501 rs55793998 chr16:68378985 G/T cg03983715 chr16:68378420 PRMT7 -0.52 -6.28 -0.32 9.99e-10 Schizophrenia; LIHC cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10089 0.857 rs7718286 chr5:127459414 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.82 0.35 4.05e-11 Ileal carcinoids; LIHC cis rs17711722 0.653 rs2460421 chr7:65491123 A/T cg11764359 chr7:65958608 NA -0.49 -6.85 -0.35 3.46e-11 Calcium levels; LIHC cis rs1801251 0.711 rs2592117 chr2:233735693 C/T cg08000102 chr2:233561755 GIGYF2 -0.71 -10.63 -0.5 5.24e-23 Coronary artery disease; LIHC cis rs600806 0.850 rs10858085 chr1:109914983 A/G cg16275483 chr1:110013120 SYPL2 -0.47 -5.92 -0.3 7.87e-9 Intelligence (multi-trait analysis); LIHC cis rs10078 0.515 rs890984 chr5:479540 A/G cg24955955 chr5:415729 AHRR 0.59 11.29 0.52 2.5e-25 Fat distribution (HIV); LIHC cis rs12926788 0.542 rs6497759 chr16:24801737 G/A cg00339695 chr16:24857497 SLC5A11 0.73 10.7 0.5 2.98e-23 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs644799 1.000 rs525404 chr11:95566520 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.49 0.46 4.04e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs801193 0.569 rs7782587 chr7:66166472 C/T cg11764359 chr7:65958608 NA 0.76 12.98 0.57 1.3e-31 Aortic root size; LIHC cis rs77633900 0.614 rs2629025 chr15:76943363 G/C cg21673338 chr15:77095150 SCAPER -0.5 -7.39 -0.37 1.11e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg25897951 chr4:1244024 CTBP1;C4orf42 -0.4 -5.71 -0.3 2.44e-8 Longevity; LIHC cis rs9858542 1.000 rs13316695 chr3:49684917 C/G cg03060546 chr3:49711283 APEH -0.63 -8.48 -0.42 6.94e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1816752 0.905 rs4769352 chr13:25000375 G/A cg22771759 chr13:24902376 NA 0.32 6.68 0.34 9.65e-11 Obesity-related traits; LIHC cis rs12477438 0.784 rs13407840 chr2:99569928 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.59 -0.38 3.1e-13 Chronic sinus infection; LIHC cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg18230493 chr5:56204884 C5orf35 -0.45 -6.21 -0.32 1.5e-9 Initial pursuit acceleration; LIHC cis rs2153535 0.541 rs1414352 chr6:8485547 A/C cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs17854409 0.764 rs73613593 chr20:61471582 T/C cg05147244 chr20:61493195 TCFL5 1.26 10.15 0.48 2.51e-21 Obesity-related traits; LIHC cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.88 -0.3 9.82e-9 Colorectal cancer; LIHC cis rs10876993 0.890 rs812304 chr12:58074853 A/C cg15848620 chr12:58087721 OS9 -0.58 -7.96 -0.4 2.5e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs6964587 0.967 rs34574955 chr7:91847550 A/C cg17063962 chr7:91808500 NA 1.04 20.48 0.74 2.12e-61 Breast cancer; LIHC cis rs7927592 0.763 rs10896327 chr11:68235275 G/C cg16797656 chr11:68205561 LRP5 0.52 9.16 0.44 5.03e-18 Total body bone mineral density; LIHC cis rs765787 0.530 rs3759893 chr15:45542950 G/T cg26924012 chr15:45694286 SPATA5L1 -0.38 -5.89 -0.3 9.39e-9 Uric acid levels; LIHC cis rs765787 0.530 rs1706834 chr15:45517854 G/A cg25801113 chr15:45476975 SHF 0.39 6.74 0.34 6.62e-11 Uric acid levels; LIHC trans rs1814175 0.645 rs28454367 chr11:50045708 G/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs4919087 0.923 rs11189037 chr10:98974707 C/G cg25902810 chr10:99078978 FRAT1 0.63 9.01 0.44 1.53e-17 Monocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15877295 chr7:138915876 UBN2 0.47 6.86 0.35 3.3e-11 Pancreatic cancer; LIHC cis rs6594499 0.542 rs7722241 chr5:110460747 T/A cg04022379 chr5:110408740 TSLP 0.56 9.24 0.45 2.75e-18 Allergic disease (asthma, hay fever or eczema); LIHC cis rs5758659 0.714 rs7245 chr22:42481849 G/A cg19513890 chr22:42538836 CYP2D7P1 0.42 8.16 0.4 6.35e-15 Cognitive function; LIHC cis rs12497850 0.543 rs6446218 chr3:49075513 A/T cg07636037 chr3:49044803 WDR6 0.95 17.04 0.68 1.37e-47 Parkinson's disease; LIHC cis rs832187 0.665 rs7627690 chr3:63900477 C/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.47 -6.65 -0.34 1.18e-10 Schizophrenia; LIHC cis rs61990749 0.597 rs6574402 chr14:78267950 C/A cg21497246 chr14:78225524 SNW1;C14orf178 -0.5 -7.53 -0.38 4.45e-13 Fibroblast growth factor basic levels; LIHC cis rs798554 0.757 rs1182198 chr7:2862906 C/T cg19524238 chr7:2802976 GNA12 -0.4 -5.8 -0.3 1.52e-8 Height; LIHC cis rs10492096 0.947 rs10774435 chr12:6616120 G/T cg13857086 chr12:6580257 VAMP1 0.59 6.44 0.33 4.14e-10 Hip geometry; LIHC cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg10360323 chr17:41437877 NA 0.4 5.97 0.31 6.07e-9 Menopause (age at onset); LIHC cis rs9303401 1.000 rs9303401 chr17:56847945 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 7.28 0.37 2.29e-12 Cognitive test performance; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03773226 chr17:37353657 CACNB1 0.46 6.97 0.35 1.69e-11 Pancreatic cancer; LIHC cis rs6840360 0.904 rs6813516 chr4:152594407 C/G cg22705602 chr4:152727874 NA -0.31 -6.42 -0.33 4.58e-10 Intelligence (multi-trait analysis); LIHC cis rs6141769 0.542 rs28542091 chr20:31301402 T/C cg13636640 chr20:31349939 DNMT3B -0.32 -5.74 -0.3 2.09e-8 Subjective well-being; LIHC cis rs769267 1.000 rs2074089 chr19:19449603 G/A cg03709012 chr19:19516395 GATAD2A -0.92 -15.98 -0.65 2.59e-43 Tonsillectomy; LIHC cis rs13108904 0.557 rs1250095 chr4:1239312 C/T cg20887711 chr4:1340912 KIAA1530 -0.71 -10.72 -0.5 2.64e-23 Obesity-related traits; LIHC cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg23982607 chr1:1823379 GNB1 -0.73 -15.06 -0.63 1.09e-39 Body mass index; LIHC cis rs1799949 0.894 rs71367985 chr17:41374463 G/A cg05368731 chr17:41323189 NBR1 0.66 10.88 0.51 7.11e-24 Menopause (age at onset); LIHC cis rs875971 0.862 rs778684 chr7:65836403 A/T cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg12292205 chr6:26970375 C6orf41 0.37 6.38 0.33 5.73e-10 Intelligence (multi-trait analysis); LIHC cis rs4727027 0.704 rs7787753 chr7:148901779 A/T cg23583168 chr7:148888333 NA -0.77 -11.63 -0.53 1.49e-26 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2153535 0.541 rs9392222 chr6:8467649 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs7249142 0.562 rs11085253 chr19:19277517 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.42 -6.89 -0.35 2.75e-11 IgG glycosylation; LIHC cis rs4970988 0.501 rs11204713 chr1:150694623 T/A cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Urate levels; LIHC cis rs950169 0.881 rs4081123 chr15:84956235 A/G cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.12e-11 Schizophrenia; LIHC cis rs988712 0.622 rs7103411 chr11:27700125 C/T cg18117895 chr11:27722066 BDNF -0.51 -7.16 -0.36 5.03e-12 Obesity; LIHC cis rs8072100 0.837 rs62074055 chr17:45771933 G/C cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.4 -6.3 -0.32 9.03e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg23835219 chr4:1244017 CTBP1;C4orf42 -0.4 -5.79 -0.3 1.57e-8 Longevity; LIHC cis rs7116495 0.609 rs7115513 chr11:71664495 T/A cg07596299 chr11:71824057 C11orf51 -0.75 -5.72 -0.3 2.3e-8 Severe influenza A (H1N1) infection; LIHC cis rs6500602 0.727 rs11076836 chr16:4569331 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.69 0.38 1.61e-13 Schizophrenia; LIHC cis rs67311347 0.955 rs4973999 chr3:40460383 G/A cg13409248 chr3:40428643 ENTPD3 0.42 7.16 0.36 5.01e-12 Renal cell carcinoma; LIHC cis rs10751667 0.857 rs6597961 chr11:976677 T/C ch.11.42038R chr11:967971 AP2A2 0.61 11.47 0.53 5.46e-26 Alzheimer's disease (late onset); LIHC cis rs11112613 0.713 rs73184081 chr12:105951745 C/T cg03607813 chr12:105948248 NA 0.62 12.24 0.55 8.48e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs1997103 1.000 rs6948112 chr7:55411302 G/A cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs1355223 0.583 rs2956074 chr11:34864880 T/C cg24088639 chr11:34937564 PDHX;APIP -0.38 -5.98 -0.31 5.69e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg07061783 chr6:25882402 NA 0.43 5.76 0.3 1.85e-8 Blood metabolite levels; LIHC cis rs2933343 0.700 rs2624910 chr3:128650275 G/C cg25356066 chr3:128598488 ACAD9 0.53 7.34 0.37 1.61e-12 IgG glycosylation; LIHC cis rs10791097 0.694 rs876641 chr11:130752040 A/C cg09137382 chr11:130731461 NA 0.42 6.25 0.32 1.19e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs909341 0.909 rs2750480 chr20:62342654 G/A cg03999872 chr20:62272968 STMN3 -0.45 -6.78 -0.34 5.24e-11 Atopic dermatitis; LIHC cis rs7432375 0.804 rs6764567 chr3:136425514 A/C cg21827317 chr3:136751795 NA -0.44 -5.79 -0.3 1.58e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs7264396 0.563 rs2425103 chr20:34312329 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.76 -0.43 9.08e-17 Total cholesterol levels; LIHC cis rs7091068 0.522 rs10882323 chr10:95483280 T/C cg20715218 chr10:95462985 C10orf4 0.52 5.97 0.31 6.1e-9 Urinary tract infection frequency; LIHC cis rs875971 0.545 rs73142233 chr7:65686280 T/A cg11764359 chr7:65958608 NA 0.49 6.78 0.34 5.36e-11 Aortic root size; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25722142 chr6:139695762 CITED2 0.41 6.16 0.32 2e-9 Pancreatic cancer; LIHC cis rs8180040 0.966 rs11711824 chr3:47468261 C/T cg27129171 chr3:47204927 SETD2 0.58 9.93 0.47 1.34e-20 Colorectal cancer; LIHC cis rs10751667 0.666 rs4074233 chr11:977685 G/A cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs826838 1.000 rs10880785 chr12:38655405 T/G cg13010199 chr12:38710504 ALG10B 0.64 7.58 0.38 3.2e-13 Heart rate; LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs6089584 0.888 rs6061981 chr20:60618973 T/C cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs6456156 0.586 rs9459862 chr6:167487011 A/G cg12798992 chr6:167411361 FGFR1OP -0.4 -6.02 -0.31 4.41e-9 Primary biliary cholangitis; LIHC cis rs9287719 0.674 rs1387566 chr2:10828650 C/T cg02829992 chr2:10710499 NA 0.39 6.01 0.31 4.74e-9 Prostate cancer; LIHC cis rs600806 0.714 rs12137189 chr1:110013215 A/G cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.45 -0.37 7.66e-13 Intelligence (multi-trait analysis); LIHC cis rs910316 0.737 rs175045 chr14:75475275 A/C cg08847533 chr14:75593920 NEK9 -0.8 -15.08 -0.63 9.28e-40 Height; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01375172 chr16:23464338 COG7 0.42 6.14 0.32 2.27e-9 Pancreatic cancer; LIHC cis rs1707322 1.000 rs4454479 chr1:46423555 G/A cg06784218 chr1:46089804 CCDC17 0.36 6.44 0.33 3.94e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs79387448 0.592 rs6728945 chr2:102986471 T/C cg09003973 chr2:102972529 NA 1.13 10.59 0.5 7.67e-23 Gut microbiota (bacterial taxa); LIHC cis rs2832191 0.791 rs2832198 chr21:30498240 C/T cg08807101 chr21:30365312 RNF160 0.54 8.4 0.41 1.24e-15 Dental caries; LIHC trans rs1493916 0.748 rs7230463 chr18:31309133 G/C cg27147174 chr7:100797783 AP1S1 -0.43 -6.61 -0.34 1.5e-10 Life satisfaction; LIHC cis rs7020830 0.894 rs12337316 chr9:37148105 G/A cg14294708 chr9:37120828 ZCCHC7 1.06 22.49 0.77 2.21e-69 Schizophrenia; LIHC cis rs7659604 0.539 rs7686200 chr4:122764553 C/T cg20573242 chr4:122745356 CCNA2 0.51 7.76 0.39 9.71e-14 Type 2 diabetes; LIHC cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg06873352 chr17:61820015 STRADA 0.74 13.02 0.58 9.8e-32 Prudent dietary pattern; LIHC cis rs763014 1.000 rs763014 chr16:675680 T/C cg04709771 chr16:646395 RAB40C 0.47 8.33 0.41 1.99e-15 Height; LIHC cis rs7208859 0.524 rs57670615 chr17:29069498 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9486719 1.000 rs35487471 chr6:96879715 C/T cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs694739 0.628 rs645078 chr11:64135298 A/C cg23796481 chr11:64053134 BAD;GPR137 0.45 6.06 0.31 3.63e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs709400 0.520 rs28583452 chr14:103938664 C/A cg26031613 chr14:104095156 KLC1 0.71 9.43 0.45 6.34e-19 Body mass index; LIHC cis rs6684514 1.000 rs12041164 chr1:156279811 G/A cg16558208 chr1:156270281 VHLL 0.54 10.17 0.48 2.13e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs477895 0.838 rs1058735 chr11:64000410 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 9.46 0.46 5.08e-19 Mean platelet volume; LIHC cis rs35306767 0.903 rs11253492 chr10:936873 T/C cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs4555082 0.750 rs2816650 chr14:105708343 C/T cg06808227 chr14:105710500 BRF1 -0.49 -6.14 -0.32 2.23e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs2282802 0.685 rs35214989 chr5:139636127 T/C cg26211634 chr5:139558579 C5orf32 0.39 5.95 0.31 6.71e-9 Intelligence (multi-trait analysis); LIHC cis rs17685 0.753 rs1637045 chr7:75703895 T/C cg04610667 chr7:75704037 NA -0.33 -5.96 -0.31 6.43e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6545883 0.894 rs9677047 chr2:61585295 C/G cg14146966 chr2:61757674 XPO1 -0.44 -7.33 -0.37 1.65e-12 Tuberculosis; LIHC cis rs35883536 1.000 rs1832121 chr1:101159476 A/G cg14515779 chr1:101123966 NA -0.66 -12.57 -0.56 4.64e-30 Monocyte count; LIHC cis rs919433 0.679 rs10166328 chr2:198511917 A/G cg10820045 chr2:198174542 NA 0.48 7.49 0.38 5.73e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs67460515 0.892 rs1478566 chr3:161030335 A/T cg03342759 chr3:160939853 NMD3 -0.62 -9.34 -0.45 1.24e-18 Parkinson's disease; LIHC cis rs796364 0.662 rs11687313 chr2:201146399 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.64 -6.11 -0.31 2.72e-9 Schizophrenia; LIHC cis rs2250402 0.510 rs2291619 chr15:40329033 C/T cg10636054 chr15:40330586 SRP14 -0.68 -8.0 -0.4 1.93e-14 Corneal curvature; LIHC cis rs7762018 0.607 rs7759404 chr6:170135728 A/G cg19338460 chr6:170058176 WDR27 -0.38 -5.74 -0.3 2.13e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs9916302 0.851 rs612209 chr17:37442713 G/C cg03013999 chr17:37608204 MED1 -0.36 -6.06 -0.31 3.53e-9 Glomerular filtration rate (creatinine); LIHC cis rs7582720 1.000 rs114155121 chr2:203718682 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 6.03 0.31 4.17e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg02290350 chr8:58132656 NA 0.49 10.56 0.5 9.22e-23 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.518 rs2569188 chr5:140008419 G/A cg19875535 chr5:140030758 IK -0.34 -5.77 -0.3 1.79e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7945705 0.967 rs7123861 chr11:8892323 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.07 0.36 8.65e-12 Hemoglobin concentration; LIHC cis rs722599 0.748 rs17093914 chr14:75363641 A/G cg08847533 chr14:75593920 NEK9 0.53 8.75 0.43 9.9e-17 IgG glycosylation; LIHC cis rs8062405 1.000 rs12444171 chr16:28845251 G/A cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6450176 1.000 rs12654393 chr5:53302620 A/C ch.5.1024479R chr5:53302184 ARL15 0.82 14.82 0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2841277 0.676 rs10438246 chr14:105410183 T/C cg21017887 chr14:105400489 NA 0.67 12.86 0.57 3.75e-31 Rheumatoid arthritis; LIHC cis rs2479724 0.846 rs2254805 chr6:41846110 T/G cg17623882 chr6:41773611 USP49 -0.56 -8.92 -0.43 2.97e-17 Menarche (age at onset); LIHC cis rs8180040 1.000 rs811115 chr3:47322133 C/T cg16586182 chr3:47516702 SCAP -0.55 -9.99 -0.48 8.46e-21 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03670153 chr3:184079754 CLCN2;POLR2H 0.39 6.15 0.32 2.17e-9 Cognitive function; LIHC cis rs3770081 1.000 rs6724025 chr2:86200835 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.51 8.12 0.4 8.3e-15 Facial emotion recognition (sad faces); LIHC trans rs875971 0.638 rs801205 chr7:66022144 C/A cg26939375 chr7:64535504 NA -0.43 -6.96 -0.35 1.72e-11 Aortic root size; LIHC cis rs561341 0.883 rs7406056 chr17:30220224 C/T cg13647721 chr17:30228624 UTP6 0.8 7.74 0.39 1.17e-13 Hip circumference adjusted for BMI; LIHC trans rs61931739 0.500 rs11615231 chr12:34413330 T/C cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs16958440 0.581 rs12386097 chr18:44673268 G/A cg17192377 chr18:44677553 HDHD2 0.51 6.25 0.32 1.24e-9 Sitting height ratio; LIHC cis rs875971 0.502 rs6460311 chr7:66111873 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.37 -7.21 -0.36 3.56e-12 Aortic root size; LIHC cis rs9309711 0.736 rs9309717 chr2:3495078 C/T cg10845886 chr2:3471009 TTC15 0.48 8.44 0.42 9.23e-16 Neurofibrillary tangles; LIHC cis rs2576037 0.526 rs2032215 chr18:44439011 A/C cg19077165 chr18:44547161 KATNAL2 -0.44 -6.73 -0.34 7.12e-11 Personality dimensions; LIHC cis rs12594515 1.000 rs12185095 chr15:45994635 G/T cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.23e-8 Waist circumference;Weight; LIHC cis rs6502050 0.871 rs6502051 chr17:80059332 A/C cg11859384 chr17:80120422 CCDC57 0.45 6.03 0.31 4.26e-9 Life satisfaction; LIHC cis rs6461049 0.800 rs3800913 chr7:2163237 A/G cg20295408 chr7:1910781 MAD1L1 -0.43 -6.4 -0.33 5.12e-10 Schizophrenia; LIHC cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg16434002 chr17:42200994 HDAC5 -0.53 -7.79 -0.39 8.33e-14 Total body bone mineral density; LIHC cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg18404041 chr3:52824283 ITIH1 0.55 9.25 0.45 2.56e-18 Bipolar disorder; LIHC cis rs8062405 1.000 rs62037364 chr16:28868695 G/A cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs3749237 1.000 rs2291542 chr3:49751585 C/T cg21659725 chr3:3221576 CRBN 0.78 12.43 0.56 1.53e-29 Resting heart rate; LIHC cis rs17002069 0.891 rs12158399 chr22:41048941 G/A cg14879645 chr22:41048474 NA 0.4 5.91 0.3 8.13e-9 Schizophrenia; LIHC cis rs6964587 0.869 rs10276682 chr7:91486070 G/A cg17063962 chr7:91808500 NA -0.95 -18.25 -0.7 1.86e-52 Breast cancer; LIHC cis rs9457247 1.000 rs2149090 chr6:167372764 T/C cg12798992 chr6:167411361 FGFR1OP -0.6 -9.94 -0.47 1.26e-20 Crohn's disease; LIHC cis rs8114671 0.628 rs6060130 chr20:33549319 C/T cg07148914 chr20:33460835 GGT7 0.62 9.57 0.46 2.3e-19 Height; LIHC cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg06873352 chr17:61820015 STRADA 0.74 13.11 0.58 4.43e-32 Prudent dietary pattern; LIHC cis rs1419980 0.673 rs4883421 chr12:7774028 A/G cg10578777 chr12:7781093 NA 0.46 8.33 0.41 1.95e-15 HDL cholesterol levels; LIHC cis rs507080 0.769 rs745663 chr11:118529595 A/G cg04173919 chr11:118528438 PHLDB1 0.32 5.81 0.3 1.42e-8 Serum metabolite levels; LIHC cis rs9640161 0.830 rs17173682 chr7:150059602 A/G cg17279839 chr7:150038598 RARRES2 0.4 8.06 0.4 1.33e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs11931598 0.509 rs13140943 chr4:6977109 A/G cg02503808 chr4:7069936 GRPEL1 0.49 7.43 0.37 8.87e-13 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs2991971 0.967 rs2356551 chr1:46009318 C/T cg24296786 chr1:45957014 TESK2 0.52 7.73 0.39 1.2e-13 High light scatter reticulocyte count; LIHC cis rs10276381 0.579 rs11520706 chr7:28202748 C/T cg23620719 chr7:28220237 JAZF1 -0.6 -6.67 -0.34 1.01e-10 Crohn's disease; LIHC cis rs752092 1.000 rs11247277 chr15:101784664 A/G cg19997662 chr15:101784653 CHSY1 -0.47 -6.0 -0.31 5.01e-9 Corneal structure; LIHC cis rs10751667 0.643 rs7396951 chr11:927355 G/A cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC cis rs798554 0.757 rs1182179 chr7:2873648 A/G cg19346786 chr7:2764209 NA -0.44 -6.35 -0.32 6.89e-10 Height; LIHC trans rs1814175 0.616 rs1794139 chr11:49910855 C/T cg03929089 chr4:120376271 NA -0.86 -16.11 -0.66 7.56e-44 Height; LIHC cis rs17125944 0.505 rs80211268 chr14:53265483 C/G cg13660082 chr14:53194042 PSMC6 -0.46 -7.57 -0.38 3.47e-13 Alzheimer's disease (late onset); LIHC cis rs17826219 0.561 rs11655876 chr17:29017150 G/A cg14067834 chr17:29058358 SUZ12P 0.57 6.04 0.31 3.99e-9 Body mass index; LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.99 21.04 0.75 1.25e-63 Height; LIHC cis rs9303401 0.573 rs34717648 chr17:56886624 T/A cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.17 0.55 1.5e-28 Cognitive test performance; LIHC trans rs11098499 0.754 rs12711071 chr4:120240934 A/G cg25214090 chr10:38739885 LOC399744 0.52 8.34 0.41 1.89e-15 Corneal astigmatism; LIHC cis rs611744 0.934 rs1668178 chr8:109191700 A/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg20887711 chr4:1340912 KIAA1530 0.53 7.61 0.38 2.61e-13 Longevity; LIHC cis rs3768617 0.510 rs3768619 chr1:183092404 C/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs1371867 0.846 rs1692006 chr8:101252462 C/T cg06002616 chr8:101225028 SPAG1 0.34 5.82 0.3 1.37e-8 Atrioventricular conduction; LIHC cis rs4665809 1.000 rs4665820 chr2:26309150 T/C cg27170947 chr2:26402098 FAM59B -0.62 -7.72 -0.39 1.27e-13 Gut microbiome composition (summer); LIHC cis rs950776 0.518 rs952216 chr15:78819202 C/T cg06917634 chr15:78832804 PSMA4 0.93 14.22 0.61 2.14e-36 Sudden cardiac arrest; LIHC cis rs4906332 0.966 rs12185021 chr14:103927805 A/G cg19000871 chr14:103996768 TRMT61A -0.47 -7.94 -0.39 2.98e-14 Coronary artery disease; LIHC trans rs10242455 0.702 rs7794068 chr7:99146873 A/T cg09045935 chr12:6379348 NA 0.91 7.86 0.39 4.94e-14 Blood metabolite levels; LIHC cis rs9640161 0.871 rs56156367 chr7:150047201 A/T cg10018233 chr7:150070692 REPIN1 0.53 8.41 0.41 1.15e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg02034447 chr16:89574710 SPG7 -0.47 -7.24 -0.36 2.96e-12 Multiple myeloma (IgH translocation); LIHC cis rs1506636 1.000 rs619575 chr7:123393460 C/T cg03229431 chr7:123269106 ASB15 -0.54 -9.93 -0.47 1.42e-20 Plateletcrit;Platelet count; LIHC cis rs3106136 0.967 rs35670996 chr4:95199479 C/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.77 -0.39 9.38e-14 Capecitabine sensitivity; LIHC cis rs765787 0.530 rs7165889 chr15:45531640 T/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs2370759 1.000 rs11594963 chr10:32625736 G/A cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs2153535 0.580 rs9393033 chr6:8521446 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.82 0.43 5.8e-17 Motion sickness; LIHC trans rs561341 1.000 rs527256 chr17:30321293 C/G cg20587970 chr11:113659929 NA -1.39 -11.8 -0.54 3.55e-27 Hip circumference adjusted for BMI; LIHC cis rs2842992 0.915 rs2758321 chr6:160071611 C/G cg19482086 chr6:160211437 TCP1;MRPL18 0.65 10.88 0.51 7.18e-24 Age-related macular degeneration (geographic atrophy); LIHC trans rs728616 0.510 rs7074356 chr10:82191334 C/T cg20463533 chr10:134705855 NA 0.29 6.22 0.32 1.48e-9 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs9814567 1.000 rs9871305 chr3:134213538 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.22 -0.55 1e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs240764 0.658 rs12664626 chr6:101195720 A/G cg09795085 chr6:101329169 ASCC3 -0.45 -6.68 -0.34 9.69e-11 Neuroticism; LIHC cis rs1799949 0.965 rs8067269 chr17:41235799 C/T cg23758822 chr17:41437982 NA 0.86 15.92 0.65 4.19e-43 Menopause (age at onset); LIHC cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg02359409 chr6:42947317 PEX6 -0.48 -6.67 -0.34 1.02e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs853679 0.517 rs4713135 chr6:28039586 G/A cg16479474 chr6:28041457 NA 0.46 6.66 0.34 1.1e-10 Depression; LIHC cis rs4780401 0.587 rs9931332 chr16:11807517 G/C cg01061890 chr16:11836724 TXNDC11 -0.65 -10.46 -0.49 2.1e-22 Rheumatoid arthritis; LIHC cis rs7959452 0.590 rs56054057 chr12:69775972 C/T cg22834771 chr12:69754056 YEATS4 -0.51 -9.1 -0.44 7.52e-18 Blood protein levels; LIHC cis rs2243480 1.000 rs34192067 chr7:65887657 C/A cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC trans rs10761482 0.500 rs2211220 chr10:62271491 A/G cg12083535 chr12:100814114 SLC17A8 -0.32 -6.45 -0.33 3.72e-10 Schizophrenia; LIHC cis rs1797081 0.967 rs811912 chr10:16859618 G/C cg23933602 chr10:16859644 RSU1 1.07 23.56 0.79 1.39e-73 Platelet distribution width; LIHC cis rs9818758 0.607 rs35060561 chr3:49255503 T/C cg07636037 chr3:49044803 WDR6 -0.81 -8.39 -0.41 1.31e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7927592 0.956 rs11228251 chr11:68244558 G/T cg16797656 chr11:68205561 LRP5 0.58 9.57 0.46 2.24e-19 Total body bone mineral density; LIHC cis rs10489202 0.632 rs3767476 chr1:168066940 C/T cg24449463 chr1:168025552 DCAF6 -0.61 -9.18 -0.44 4.22e-18 Schizophrenia; LIHC cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.83 8.27 0.41 2.93e-15 Platelet count; LIHC cis rs3849570 1.000 rs11711331 chr3:81819040 A/G cg07356753 chr3:81810745 GBE1 0.63 10.49 0.49 1.68e-22 Waist circumference;Body mass index; LIHC cis rs11122272 0.735 rs2486728 chr1:231535883 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.84e-22 Hemoglobin concentration; LIHC cis rs2108622 0.727 rs12610189 chr19:15978641 T/G cg13772218 chr19:15982569 NA 0.37 7.84 0.39 5.87e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs4665809 1.000 rs4665816 chr2:26305094 G/C cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.84 -0.43 5.27e-17 Gut microbiome composition (summer); LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs4919694 1.000 rs58700372 chr10:104800205 T/C cg04362960 chr10:104952993 NT5C2 1.14 8.87 0.43 4.02e-17 Arsenic metabolism; LIHC cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg24675658 chr1:53192096 ZYG11B 0.57 9.01 0.44 1.52e-17 Monocyte count; LIHC cis rs9457247 0.765 rs3752520 chr6:167436159 T/C cg07741184 chr6:167504864 NA 0.31 7.2 0.36 3.95e-12 Crohn's disease; LIHC cis rs2019137 0.589 rs7560701 chr2:114026882 C/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.44 5.97 0.31 6.07e-9 Lymphocyte counts; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18678067 chr19:52674854 ZNF836 0.47 6.28 0.32 9.99e-10 Pancreatic cancer; LIHC cis rs782590 0.967 rs1975484 chr2:55803167 T/A cg18811423 chr2:55921094 PNPT1 0.93 15.16 0.63 4.39e-40 Metabolic syndrome; LIHC cis rs2153535 0.580 rs1120392 chr6:8487053 C/A cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs7927592 0.956 rs7116899 chr11:68385535 G/T cg01657329 chr11:68192670 LRP5 -0.48 -6.29 -0.32 9.92e-10 Total body bone mineral density; LIHC cis rs921968 0.643 rs545460 chr2:219392159 A/G cg17980119 chr2:219472607 PLCD4 0.35 5.94 0.31 7.14e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs35306767 0.855 rs12771179 chr10:872347 A/G cg26597838 chr10:835615 NA 1.5 16.55 0.67 1.29e-45 Eosinophil percentage of granulocytes; LIHC cis rs6748734 1.000 rs7604393 chr2:241825034 T/G cg20140201 chr2:241835670 C2orf54 -0.46 -6.25 -0.32 1.22e-9 Urinary metabolites; LIHC cis rs9921222 0.597 rs7193109 chr16:413523 T/G cg26913058 chr16:419975 MRPL28 -0.58 -8.47 -0.42 7.23e-16 Bone mineral density (spine);Bone mineral density; LIHC cis rs7771547 0.573 rs522179 chr6:36391605 G/A cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Platelet distribution width; LIHC cis rs6748734 1.000 rs4675874 chr2:241819796 A/G cg20140201 chr2:241835670 C2orf54 0.46 6.2 0.32 1.63e-9 Urinary metabolites; LIHC cis rs853679 0.517 rs9295761 chr6:28147987 A/G cg16479474 chr6:28041457 NA 0.46 6.44 0.33 4.11e-10 Depression; LIHC cis rs11758351 1.000 rs16891405 chr6:26204506 A/G cg11342453 chr6:26196699 NA 0.53 5.79 0.3 1.63e-8 Gout;Renal underexcretion gout; LIHC cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg06466757 chr4:1255808 NA 0.34 5.79 0.3 1.61e-8 Obesity-related traits; LIHC cis rs7635838 0.654 rs346083 chr3:11280017 T/C cg00170343 chr3:11313890 ATG7 0.58 8.65 0.42 1.99e-16 HDL cholesterol; LIHC cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg13047869 chr3:10149882 C3orf24 0.51 5.88 0.3 9.55e-9 Alzheimer's disease; LIHC cis rs7945718 0.967 rs7927470 chr11:12748899 A/T cg25843174 chr11:12811716 TEAD1 0.36 8.24 0.41 3.64e-15 Educational attainment (years of education); LIHC cis rs12971120 0.891 rs3764510 chr18:72166846 A/G cg26446133 chr18:72167187 CNDP2 -0.8 -14.77 -0.62 1.64e-38 Refractive error; LIHC cis rs7412746 0.563 rs3768013 chr1:150815411 G/A cg18016565 chr1:150552671 MCL1 0.51 9.63 0.46 1.46e-19 Melanoma; LIHC cis rs2303745 0.589 rs1465576 chr19:17398487 G/A cg02221750 chr19:17393354 ANKLE1 -0.41 -5.85 -0.3 1.16e-8 Systemic lupus erythematosus; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg14004847 chr7:1930337 MAD1L1 -0.42 -5.92 -0.3 7.75e-9 Bipolar disorder and schizophrenia; LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg03874509 chr1:107600012 PRMT6 -0.77 -12.17 -0.55 1.47e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg03785755 chr6:26196794 NA 0.51 5.97 0.31 5.8e-9 Gout;Renal underexcretion gout; LIHC cis rs798554 0.836 rs798500 chr7:2790685 C/T cg04166393 chr7:2884313 GNA12 -0.46 -6.4 -0.33 5.18e-10 Height; LIHC cis rs13217239 0.646 rs12527111 chr6:27006475 C/T cg18867708 chr6:26865862 GUSBL1 0.51 7.78 0.39 8.55e-14 Schizophrenia; LIHC cis rs1059312 0.771 rs7974764 chr12:129296588 G/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.77 -16.8 -0.67 1.3e-46 Systemic lupus erythematosus; LIHC cis rs801193 0.935 rs11772264 chr7:66176387 T/C cg14393609 chr7:65229607 NA 0.37 5.77 0.3 1.82e-8 Aortic root size; LIHC cis rs3862260 0.509 rs1045827 chr1:120162442 C/T cg16322792 chr1:120165303 ZNF697 -0.53 -9.69 -0.46 8.56e-20 Systemic lupus erythematosus; LIHC cis rs1707322 0.691 rs61784803 chr1:46179271 C/A cg06784218 chr1:46089804 CCDC17 -0.42 -7.78 -0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7772486 0.719 rs2206141 chr6:146086192 A/G cg23711669 chr6:146136114 FBXO30 -0.75 -13.37 -0.59 4.42e-33 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15312298 chr8:127570908 FAM84B 0.44 7.78 0.39 8.75e-14 Cognitive function; LIHC cis rs10751667 0.600 rs7394783 chr11:1005108 C/T cg10932868 chr11:921992 NA -0.33 -6.23 -0.32 1.4e-9 Alzheimer's disease (late onset); LIHC cis rs8180040 0.966 rs11130128 chr3:47486632 T/C cg16586182 chr3:47516702 SCAP 0.61 11.81 0.54 3.13e-27 Colorectal cancer; LIHC cis rs8180040 0.764 rs6794193 chr3:47114904 T/C cg27129171 chr3:47204927 SETD2 0.68 11.98 0.54 7.54e-28 Colorectal cancer; LIHC cis rs826838 0.933 rs980573 chr12:39127811 T/C cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg25894440 chr7:65020034 NA -0.51 -5.85 -0.3 1.13e-8 Diabetic kidney disease; LIHC cis rs1144333 0.655 rs931506 chr1:76401349 T/C cg03433033 chr1:76189801 ACADM 0.53 7.59 0.38 2.97e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs1577917 1.000 rs36096931 chr6:86693134 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.69 -0.46 8.94e-20 Response to antipsychotic treatment; LIHC cis rs9611565 0.879 rs2235845 chr22:41729294 T/G cg03806693 chr22:41940476 POLR3H -0.45 -5.92 -0.3 7.75e-9 Vitiligo; LIHC trans rs617791 0.530 rs10896073 chr11:65762814 T/C cg17712092 chr4:129076599 LARP1B -0.56 -6.8 -0.35 4.55e-11 Breast cancer; LIHC cis rs7727544 0.735 rs274557 chr5:131721204 T/C cg24060327 chr5:131705240 SLC22A5 0.58 8.24 0.41 3.7e-15 Blood metabolite levels; LIHC cis rs7914558 1.000 rs10786740 chr10:104935593 G/C cg15744005 chr10:104629667 AS3MT -0.39 -8.88 -0.43 3.78e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs317689 0.690 rs604168 chr12:69671158 C/T cg20891283 chr12:69753455 YEATS4 0.52 7.61 0.38 2.64e-13 Response to diuretic therapy; LIHC cis rs929354 0.772 rs1182442 chr7:157026633 G/A cg17757837 chr7:157058334 UBE3C -0.72 -11.73 -0.54 6.15e-27 Body mass index; LIHC trans rs2749592 0.918 rs11011388 chr10:38155210 C/T cg17830980 chr10:43048298 ZNF37B 0.4 7.22 0.36 3.42e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs600806 0.850 rs3768494 chr1:109935427 A/G cg16275483 chr1:110013120 SYPL2 -0.47 -5.92 -0.3 7.87e-9 Intelligence (multi-trait analysis); LIHC cis rs1401999 1.000 rs1402003 chr3:183642879 C/T cg01324343 chr3:183735012 ABCC5 0.72 11.81 0.54 3.07e-27 Anterior chamber depth; LIHC cis rs7542091 0.704 rs7537294 chr1:210043777 A/G cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC trans rs4819388 0.915 rs4818892 chr21:45650085 A/G cg17383793 chr5:52405638 MOCS2 0.4 6.3 0.32 9.2e-10 Celiac disease; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg14257396 chr1:107603778 NA -0.37 -6.15 -0.32 2.17e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7662987 0.517 rs2851268 chr4:100027878 A/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs6450176 1.000 rs3776717 chr5:53298762 G/A ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 1.04e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6570726 0.846 rs372904 chr6:145887425 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.9 0.3 8.52e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs801193 0.569 rs10950050 chr7:66239588 A/C cg18876405 chr7:65276391 NA 0.31 5.74 0.3 2.14e-8 Aortic root size; LIHC cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg13409248 chr3:40428643 ENTPD3 -0.51 -8.62 -0.42 2.46e-16 Renal cell carcinoma; LIHC cis rs11605275 1.000 rs16937347 chr11:20026717 A/G cg14835545 chr11:20032148 NAV2 -0.64 -6.23 -0.32 1.4e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.85 8.64 0.42 2.25e-16 Platelet count; LIHC cis rs2795502 0.882 rs2744087 chr10:43340270 A/C cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs7487075 0.619 rs10748450 chr12:46857102 C/T cg23829395 chr12:46796953 NA 0.33 5.9 0.3 8.55e-9 Itch intensity from mosquito bite; LIHC cis rs6582630 0.519 rs4002440 chr12:38485012 A/G cg13010199 chr12:38710504 ALG10B 0.46 6.14 0.31 2.35e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs9322817 0.691 rs2499664 chr6:105301484 C/G cg02098413 chr6:105308735 HACE1 0.43 8.14 0.4 7.69e-15 Thyroid stimulating hormone; LIHC cis rs8084351 0.577 rs8088666 chr18:50648093 A/G cg24270629 chr18:50823537 DCC 0.44 6.49 0.33 3.03e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs6714710 0.603 rs35424768 chr2:98395653 A/C cg26665480 chr2:98280029 ACTR1B 0.44 6.22 0.32 1.44e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs7520050 1.000 rs785473 chr1:46516863 T/C cg03146154 chr1:46216737 IPP -0.36 -5.94 -0.31 7.06e-9 Red blood cell count;Reticulocyte count; LIHC cis rs155076 1.000 rs564685 chr13:21846879 A/G cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.3e-30 White matter hyperintensity burden; LIHC cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg19302996 chr17:73780495 UNK -0.52 -6.15 -0.32 2.22e-9 Psoriasis; LIHC cis rs4808199 0.948 rs968525 chr19:19459215 C/T cg03709012 chr19:19516395 GATAD2A 0.99 15.97 0.65 2.6900000000000002e-43 Nonalcoholic fatty liver disease; LIHC trans rs2270927 0.510 rs4566771 chr5:75576522 C/T cg13563193 chr19:33072644 PDCD5 0.99 9.43 0.45 6.56e-19 Mean corpuscular volume; LIHC cis rs736408 0.677 rs1042779 chr3:52821011 A/G cg10802521 chr3:52805072 NEK4 -0.4 -6.37 -0.33 6e-10 Bipolar disorder; LIHC cis rs12644436 0.628 rs4693889 chr4:88783723 C/T cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs9733 0.650 rs61820165 chr1:150555987 C/T cg17724175 chr1:150552817 MCL1 -0.37 -7.36 -0.37 1.35e-12 Tonsillectomy; LIHC cis rs12893668 0.572 rs34000399 chr14:104101417 T/C cg24130564 chr14:104152367 KLC1 -0.55 -9.35 -0.45 1.16e-18 Reticulocyte count; LIHC trans rs11098499 0.913 rs12186259 chr4:120152039 C/T cg25214090 chr10:38739885 LOC399744 0.53 8.01 0.4 1.76e-14 Corneal astigmatism; LIHC cis rs68170813 0.521 rs61673847 chr7:106892431 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs9467773 1.000 rs9393728 chr6:26509330 C/G cg09904177 chr6:26538194 HMGN4 0.66 13.85 0.6 6.03e-35 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.566 rs1811673 chr11:49602134 A/G cg18944383 chr4:111397179 ENPEP 0.36 8.31 0.41 2.33e-15 Height; LIHC cis rs2842992 0.789 rs4709370 chr6:160210061 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.25 0.55 7.41e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs35110281 0.774 rs9978811 chr21:44998683 C/T cg21573476 chr21:45109991 RRP1B -0.53 -9.94 -0.47 1.27e-20 Mean corpuscular volume; LIHC cis rs6500602 0.727 rs2160567 chr16:4535557 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 6.01 0.31 4.66e-9 Schizophrenia; LIHC cis rs5769707 0.749 rs7286706 chr22:50058346 G/C cg07959070 chr22:50026188 C22orf34 -0.29 -7.03 -0.36 1.15e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg02993280 chr1:107599747 PRMT6 0.66 10.55 0.5 1.03e-22 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7833986 0.501 rs2953901 chr8:56981824 C/A cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.76 0.43 9.13e-17 Height; LIHC cis rs8067354 0.872 rs2645466 chr17:57853214 A/C cg02344993 chr17:57696989 CLTC 0.53 8.5 0.42 5.82e-16 Hemoglobin concentration; LIHC cis rs3096299 0.933 rs3096297 chr16:89453155 T/G cg06640241 chr16:89574553 SPG7 0.65 10.35 0.49 5.15e-22 Multiple myeloma (IgH translocation); LIHC trans rs75804782 0.520 rs34058921 chr2:239318665 C/T cg01134436 chr17:81009848 B3GNTL1 0.77 6.29 0.32 9.7e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs763121 0.853 rs1043441 chr22:39130964 C/T cg21395723 chr22:39101663 GTPBP1 0.37 6.02 0.31 4.4e-9 Menopause (age at onset); LIHC cis rs7523273 0.526 rs12132968 chr1:207884292 T/C cg22525895 chr1:207977042 MIR29B2 0.49 7.14 0.36 5.67e-12 Schizophrenia; LIHC cis rs67460515 0.531 rs13315565 chr3:160754626 G/C cg17135325 chr3:160939158 NMD3 0.52 7.21 0.36 3.67e-12 Parkinson's disease; LIHC cis rs9807989 0.507 rs10439410 chr2:102990788 A/C cg03938978 chr2:103052716 IL18RAP -0.31 -5.89 -0.3 9.45e-9 Asthma; LIHC cis rs6570726 0.791 rs9403734 chr6:145931459 C/G cg23711669 chr6:146136114 FBXO30 0.73 12.14 0.55 1.95e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs8114671 0.527 rs3736802 chr20:33604042 T/C cg07148914 chr20:33460835 GGT7 -0.47 -6.89 -0.35 2.61e-11 Height; LIHC cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.82e-13 Bipolar disorder; LIHC cis rs12220238 0.915 rs61045754 chr10:76153125 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.76 0.3 1.85e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs2839186 0.681 rs13047198 chr21:47701835 T/C cg00815214 chr21:47717953 NA -0.36 -5.86 -0.3 1.06e-8 Testicular germ cell tumor; LIHC cis rs11792861 0.926 rs10512391 chr9:111809530 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.39 0.41 1.27e-15 Menarche (age at onset); LIHC cis rs1559088 0.545 rs7257431 chr19:33566924 A/G cg17764715 chr19:33622953 WDR88 0.55 7.4 0.37 1.04e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9473924 0.580 rs67092917 chr6:50815333 G/T cg14470998 chr6:50812995 TFAP2B 0.93 10.62 0.5 6.08e-23 Body mass index; LIHC cis rs7927592 0.913 rs6591346 chr11:68384618 T/A cg01657329 chr11:68192670 LRP5 -0.48 -6.39 -0.33 5.51e-10 Total body bone mineral density; LIHC cis rs3020736 0.500 rs6002616 chr22:42504679 A/G cg15557168 chr22:42548783 NA 0.44 7.0 0.35 1.32e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs72781680 0.716 rs2551334 chr2:24000396 G/A cg08917208 chr2:24149416 ATAD2B 0.59 5.91 0.3 8.07e-9 Lymphocyte counts; LIHC trans rs2727020 0.704 rs2988340 chr11:49176057 C/T cg18944383 chr4:111397179 ENPEP 0.26 6.38 0.33 5.7e-10 Coronary artery disease; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg18705916 chr5:1800069 MRPL36;NDUFS6 -0.4 -6.07 -0.31 3.45e-9 Alopecia areata; LIHC cis rs7769051 0.808 rs1467404 chr6:133090141 A/G cg07930552 chr6:133119739 C6orf192 -0.73 -7.0 -0.35 1.33e-11 Type 2 diabetes nephropathy; LIHC cis rs55702914 0.905 rs787988 chr2:198200802 C/T cg03934865 chr2:198174659 NA -0.4 -5.87 -0.3 1.06e-8 Major depression and alcohol dependence; LIHC cis rs7927592 0.913 rs6591340 chr11:68297636 A/G cg01657329 chr11:68192670 LRP5 -0.46 -6.02 -0.31 4.44e-9 Total body bone mineral density; LIHC cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg24101359 chr6:42928495 GNMT 0.46 5.95 0.31 6.73e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg22105103 chr4:187893119 NA 0.33 8.15 0.4 6.75e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs1371867 0.846 rs1692006 chr8:101252462 C/T cg06636551 chr8:101224915 SPAG1 0.5 9.41 0.45 7.56e-19 Atrioventricular conduction; LIHC trans rs17711722 0.503 rs453835 chr7:65511159 T/A cg10756647 chr7:56101905 PSPH 0.44 6.46 0.33 3.71e-10 Calcium levels; LIHC cis rs713477 0.967 rs12431542 chr14:55913078 T/C cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.46e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs12142240 0.698 rs56130131 chr1:46861306 A/C cg14993813 chr1:46806288 NSUN4 -0.64 -5.77 -0.3 1.73e-8 Menopause (age at onset); LIHC cis rs7937682 0.632 rs10789850 chr11:111750829 C/T cg09085632 chr11:111637200 PPP2R1B 0.93 13.4 0.59 3.23e-33 Primary sclerosing cholangitis; LIHC cis rs68170813 0.559 rs78267892 chr7:106823734 C/T cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg11764359 chr7:65958608 NA 0.69 9.37 0.45 1.04e-18 Calcium levels; LIHC cis rs10276381 0.786 rs10255700 chr7:28220228 C/T cg23620719 chr7:28220237 JAZF1 0.65 8.1 0.4 9.57e-15 Crohn's disease; LIHC cis rs3749237 0.595 rs3870338 chr3:49557051 A/G cg06212747 chr3:49208901 KLHDC8B 0.44 5.83 0.3 1.31e-8 Resting heart rate; LIHC cis rs941873 0.868 rs7898 chr10:81114959 C/T cg09469691 chr10:81107165 PPIF 0.67 10.26 0.49 1e-21 Height; LIHC cis rs6977660 0.652 rs10274428 chr7:19850592 C/T cg07541023 chr7:19748670 TWISTNB 0.39 5.94 0.31 6.98e-9 Thyroid stimulating hormone; LIHC cis rs2243480 0.522 rs778717 chr7:65848151 G/C cg18252515 chr7:66147081 NA -1.26 -14.23 -0.61 2.02e-36 Diabetic kidney disease; LIHC cis rs8114671 0.551 rs4911162 chr20:33411425 G/C cg07148914 chr20:33460835 GGT7 0.59 8.57 0.42 3.53e-16 Height; LIHC cis rs9324022 0.929 rs1004574 chr14:101178067 C/G cg18089426 chr14:101175970 NA 0.47 5.97 0.31 5.8e-9 Plateletcrit; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg22800045 chr5:56110881 MAP3K1 0.65 8.32 0.41 2.05e-15 Initial pursuit acceleration; LIHC cis rs61990749 0.597 rs4632066 chr14:78247282 C/T cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.79 0.39 7.83e-14 Fibroblast growth factor basic levels; LIHC cis rs12477438 0.520 rs11695379 chr2:99742161 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.47 0.77 2.52e-69 Chronic sinus infection; LIHC cis rs9649213 0.593 rs6465673 chr7:97968887 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.97 -0.31 5.97e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs1912483 0.505 rs3760372 chr17:45380002 T/C cg25173405 chr17:45401733 C17orf57 -0.55 -6.82 -0.35 4.06e-11 Coronary artery disease; LIHC cis rs9534288 0.830 rs2404963 chr13:46632836 C/T cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs57590327 0.716 rs4352391 chr3:81802318 T/C cg07356753 chr3:81810745 GBE1 -0.54 -7.84 -0.39 5.72e-14 Extraversion; LIHC trans rs1555543 0.538 rs7416802 chr1:96909292 G/C cg10631902 chr5:14652156 NA -0.32 -6.59 -0.34 1.64e-10 Body mass index; LIHC cis rs116095464 0.558 rs3213838 chr5:223890 G/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs526821 0.532 rs578067 chr11:55313690 T/G cg04317927 chr11:55418816 OR4S2 0.47 9.04 0.44 1.17e-17 Pediatric bone mineral density (spine); LIHC cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg26939375 chr7:64535504 NA 0.47 7.17 0.36 4.64e-12 Aortic root size; LIHC trans rs2262909 0.962 rs12609368 chr19:22263996 T/C cg05197062 chr11:11642011 GALNTL4 0.43 6.12 0.31 2.57e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs9549367 0.713 rs3024757 chr13:113823186 G/T cg00898013 chr13:113819073 PROZ -0.44 -7.2 -0.36 3.95e-12 Platelet distribution width; LIHC cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs10464366 0.746 rs34792397 chr7:39146331 G/A cg18850127 chr7:39170497 POU6F2 0.44 7.93 0.39 3.23e-14 IgG glycosylation; LIHC cis rs7523273 0.554 rs2761434 chr1:207917499 C/T cg22525895 chr1:207977042 MIR29B2 -0.65 -7.99 -0.4 2.14e-14 Schizophrenia; LIHC cis rs79387448 0.638 rs13405222 chr2:102981891 T/C cg09003973 chr2:102972529 NA 1.14 9.45 0.45 5.65e-19 Gut microbiota (bacterial taxa); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08151832 chr16:66835414 CCDC79 -0.41 -6.27 -0.32 1.09e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10463316 0.744 rs6579869 chr5:150763621 G/A cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.05e-10 Metabolite levels (Pyroglutamine); LIHC trans rs4332037 0.950 rs7807014 chr7:1939021 T/C cg11693508 chr17:37793320 STARD3 0.73 7.55 0.38 4.04e-13 Bipolar disorder; LIHC cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg02951883 chr7:2050386 MAD1L1 0.79 13.28 0.58 9.66e-33 Bipolar disorder and schizophrenia; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg11060661 chr22:24314208 DDT;DDTL 0.6 10.25 0.48 1.08e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2845885 0.793 rs56241103 chr11:63882364 C/T cg19006947 chr11:64034861 PLCB3 -0.46 -7.21 -0.36 3.51e-12 Body mass index; LIHC cis rs10097731 0.901 rs10464932 chr8:82042901 T/G cg25230327 chr8:82042993 NA -0.59 -8.01 -0.4 1.81e-14 Serum total protein level; LIHC trans rs7395662 0.500 rs7951327 chr11:48925359 C/T cg15704280 chr7:45808275 SEPT13 -0.52 -7.75 -0.39 1.05e-13 HDL cholesterol; LIHC cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg04025307 chr7:1156635 C7orf50 0.55 9.29 0.45 1.82e-18 Longevity;Endometriosis; LIHC cis rs2074193 0.826 rs215347 chr12:47734161 A/G cg02516419 chr12:47771422 NA 0.42 6.6 0.34 1.59e-10 Migraine with aura; LIHC cis rs10540 0.908 rs71487293 chr11:486414 G/A cg03576123 chr11:487126 PTDSS2 -1.0 -7.64 -0.38 2.18e-13 Body mass index; LIHC cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg12419862 chr22:24373484 LOC391322 -0.68 -10.4 -0.49 3.33e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7903847 0.642 rs11189178 chr10:99143272 T/G cg20016023 chr10:99160130 RRP12 -0.41 -6.5 -0.33 2.81e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7940866 0.834 rs10894298 chr11:130840571 C/A cg12179176 chr11:130786555 SNX19 0.64 9.23 0.45 2.97e-18 Schizophrenia; LIHC cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg03354898 chr7:1950403 MAD1L1 -0.38 -5.72 -0.3 2.3e-8 Bipolar disorder and schizophrenia; LIHC cis rs3862260 0.509 rs10923879 chr1:120163831 A/G cg11530693 chr1:120165357 ZNF697 0.48 7.59 0.38 3.02e-13 Systemic lupus erythematosus; LIHC cis rs6089584 1.000 rs6089581 chr20:60562394 G/A cg13770153 chr20:60521292 NA -0.35 -6.9 -0.35 2.53e-11 Body mass index; LIHC cis rs1419980 0.586 rs10845548 chr12:7777657 T/A cg10578777 chr12:7781093 NA -0.48 -8.55 -0.42 4.06e-16 HDL cholesterol levels; LIHC cis rs6430585 0.583 rs9636213 chr2:136589278 G/A cg25344623 chr2:136566232 LCT 0.33 5.78 0.3 1.65e-8 Corneal structure; LIHC cis rs11122272 0.735 rs2790885 chr1:231529925 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC trans rs3743102 0.591 rs10520565 chr15:83255074 C/T cg01542190 chr22:50604728 NA -0.52 -6.51 -0.33 2.64e-10 Colorectal adenoma (advanced); LIHC cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.825 rs9616780 chr22:50292763 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -9.16 -0.44 4.85e-18 Schizophrenia; LIHC cis rs10792665 0.670 rs3763813 chr11:82613021 A/T cg24227371 chr11:82718527 RAB30 -0.27 -6.35 -0.32 6.83e-10 Obesity-related traits; LIHC cis rs10751667 0.666 rs10902241 chr11:949129 G/A cg06064525 chr11:970664 AP2A2 -0.56 -15.09 -0.63 8.65e-40 Alzheimer's disease (late onset); LIHC cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg12311346 chr5:56204834 C5orf35 0.61 7.77 0.39 8.98e-14 Initial pursuit acceleration; LIHC cis rs548181 0.545 rs76179820 chr11:125616379 A/G cg03464685 chr11:125439445 EI24 -0.79 -8.42 -0.41 1.03e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1144333 0.850 rs1251274 chr1:76288587 T/C cg22875332 chr1:76189707 ACADM -0.42 -6.72 -0.34 7.62e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg27432699 chr2:27873401 GPN1 -0.54 -7.8 -0.39 7.54e-14 Menopause (age at onset); LIHC cis rs2257205 0.667 rs8071942 chr17:56778271 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -6.56 -0.33 2e-10 Pancreatic cancer; LIHC cis rs9715521 0.677 rs17493148 chr4:59861895 T/C cg11281224 chr4:60001000 NA -0.34 -6.32 -0.32 8.03e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs2980439 0.525 rs2980508 chr8:8171732 C/T cg06710121 chr8:12235606 FAM66A -0.36 -6.34 -0.32 7.25e-10 Neuroticism; LIHC trans rs7246657 0.943 rs9676967 chr19:37928089 G/C cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs1055129 0.560 rs2666003 chr17:73942976 G/A cg14829360 chr17:73884958 NA -0.37 -6.32 -0.32 8.22e-10 White matter hyperintensity burden; LIHC cis rs7954584 0.520 rs1169095 chr12:122465738 G/A cg22168489 chr12:122356033 WDR66 -0.36 -5.94 -0.31 7.04e-9 Mean corpuscular volume; LIHC cis rs7772486 0.641 rs67882056 chr6:146416301 T/C cg13319975 chr6:146136371 FBXO30 -0.56 -8.81 -0.43 6.58e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs11626933 1.000 rs61989986 chr14:90739180 G/A cg14092571 chr14:90743983 NA -0.91 -15.04 -0.63 1.37e-39 Gut microbiota (bacterial taxa); LIHC cis rs10789491 1.000 rs10749863 chr1:47174328 C/T cg15501359 chr1:47185051 KIAA0494 0.8 11.35 0.52 1.51e-25 Response to hepatitis C treatment; LIHC trans rs61931739 0.534 rs7965503 chr12:34199349 A/G cg26384229 chr12:38710491 ALG10B 0.55 7.05 0.36 1.01e-11 Morning vs. evening chronotype; LIHC trans rs12692119 0.764 rs61730218 chr2:127656857 G/A cg13995918 chr5:1280305 TERT 0.43 6.05 0.31 3.89e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs7945705 0.902 rs10769979 chr11:9010659 C/T cg12365402 chr11:9010492 NRIP3 0.34 8.66 0.42 1.93e-16 Hemoglobin concentration; LIHC cis rs7078219 0.505 rs4129132 chr10:101284637 T/G cg06854084 chr10:101292507 NKX2-3 -0.33 -6.06 -0.31 3.63e-9 Dental caries; LIHC cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.12 17.71 0.69 2.8e-50 Gut microbiome composition (summer); LIHC trans rs2797160 1.000 rs2797158 chr6:126009398 G/A cg05039488 chr6:79577232 IRAK1BP1 0.46 6.5 0.33 2.88e-10 Endometrial cancer; LIHC cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg07414643 chr4:187882934 NA 0.24 6.15 0.32 2.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10876993 0.728 rs1082503 chr12:58036717 G/A cg18357645 chr12:58087776 OS9 0.49 8.09 0.4 1.06e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs2404602 0.684 rs62026898 chr15:76944371 C/A cg23625390 chr15:77176239 SCAPER -0.55 -9.13 -0.44 6.31e-18 Blood metabolite levels; LIHC cis rs7572733 0.576 rs1865586 chr2:198758868 C/T cg10820045 chr2:198174542 NA -0.47 -7.04 -0.36 1.03e-11 Dermatomyositis; LIHC cis rs734999 1.000 rs2016366 chr1:2513678 A/T cg18854424 chr1:2615690 NA 0.33 7.01 0.35 1.27e-11 Ulcerative colitis; LIHC cis rs2839186 0.967 rs2839191 chr21:47695395 C/G cg12379764 chr21:47803548 PCNT -0.58 -8.39 -0.41 1.27e-15 Testicular germ cell tumor; LIHC cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs7224737 1.000 rs8070446 chr17:40285879 G/A cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs11588062 1.000 rs11588062 chr1:46779764 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.59 9.34 0.45 1.28e-18 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1538970 0.924 rs6657284 chr1:45879088 T/C cg05343316 chr1:45956843 TESK2 0.58 8.52 0.42 5.21e-16 Platelet count; LIHC cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg05368731 chr17:41323189 NBR1 0.71 12.31 0.55 4.27e-29 Menopause (age at onset); LIHC cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs651907 0.557 rs11917682 chr3:101355427 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.08 -0.31 3.29e-9 Colorectal cancer; LIHC cis rs1144333 0.655 rs75578876 chr1:76395586 A/C cg03433033 chr1:76189801 ACADM 0.53 7.55 0.38 4.02e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg24101359 chr6:42928495 GNMT 0.44 5.99 0.31 5.46e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1348850 0.554 rs11679519 chr2:178432110 C/T cg27490568 chr2:178487706 NA 0.83 9.93 0.47 1.39e-20 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs344364 0.511 rs2917515 chr16:1945271 G/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.58 -7.37 -0.37 1.31e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg13271783 chr10:134563150 INPP5A -0.5 -6.51 -0.33 2.7e-10 Migraine; LIHC cis rs1443512 0.755 rs1373160 chr12:54340383 A/G cg25024717 chr12:54324583 NA -0.32 -6.18 -0.32 1.8e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs807669 0.586 rs5746671 chr22:19160899 A/G cg02655711 chr22:19163373 SLC25A1 0.37 6.91 0.35 2.32e-11 Metabolite levels; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg09271671 chr16:70432453 ST3GAL2 0.4 6.04 0.31 4.01e-9 Immature fraction of reticulocytes; LIHC cis rs10504229 0.610 rs6987118 chr8:58147851 G/T cg08219700 chr8:58056026 NA 0.43 5.88 0.3 1e-8 Developmental language disorder (linguistic errors); LIHC trans rs6500650 0.557 rs3743845 chr16:5040717 C/T cg26446499 chr5:77253555 NA -0.33 -6.05 -0.31 3.76e-9 Cancer; LIHC cis rs9427116 0.502 rs9426829 chr1:154592201 T/C cg17218026 chr1:154582156 ADAR 0.36 6.98 0.35 1.52e-11 Blood protein levels; LIHC cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg13271783 chr10:134563150 INPP5A -0.53 -6.77 -0.34 5.47e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.6 0.56 3.7e-30 Prudent dietary pattern; LIHC cis rs2625529 0.530 rs2959930 chr15:72598614 A/G cg16672083 chr15:72433130 SENP8 -0.33 -6.07 -0.31 3.47e-9 Red blood cell count; LIHC cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg07414643 chr4:187882934 NA -0.23 -5.71 -0.3 2.39e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs8030605 0.704 rs72742607 chr15:56670259 G/T cg01710580 chr16:598674 SOLH -0.67 -6.07 -0.31 3.31e-9 Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11212260 0.655 rs11212172 chr11:107212729 C/A cg25435332 chr11:107328525 CWF19L2 0.81 7.77 0.39 9.47e-14 IgG glycosylation; LIHC trans rs950169 0.610 rs34529571 chr15:84691807 A/G cg24036039 chr1:3397125 ARHGEF16 0.37 6.19 0.32 1.71e-9 Schizophrenia; LIHC cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -10.26 -0.48 1.08e-21 Platelet count; LIHC trans rs11722228 0.522 rs1109472 chr4:10134448 C/G cg26043149 chr18:55253948 FECH 0.95 14.57 0.62 9.62e-38 Gout;Urate levels;Serum uric acid levels; LIHC trans rs8108034 0.920 rs30480 chr19:39807213 A/G cg24033503 chr14:101005128 BEGAIN -0.52 -6.4 -0.33 5.09e-10 Lung adenocarcinoma; LIHC cis rs7551222 0.752 rs16853958 chr1:204528344 A/C cg20240347 chr1:204465584 NA -0.37 -7.85 -0.39 5.36e-14 Schizophrenia; LIHC cis rs2463822 0.688 rs7121684 chr11:62162389 T/C cg06239285 chr11:62104954 ASRGL1 -0.92 -6.26 -0.32 1.14e-9 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs3096299 0.781 rs3102381 chr16:89409720 G/C cg08822215 chr16:89438651 ANKRD11 -0.44 -6.93 -0.35 2.11e-11 Multiple myeloma (IgH translocation); LIHC cis rs6089584 0.888 rs6061981 chr20:60618973 T/C cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs9921222 0.500 rs8046256 chr16:393948 C/T cg26944245 chr16:421049 TMEM8A;MRPL28 0.42 6.6 0.34 1.54e-10 Bone mineral density (spine);Bone mineral density; LIHC cis rs12594515 1.000 rs11070464 chr15:45984776 C/A cg06207120 chr15:45996521 NA 0.33 6.46 0.33 3.55e-10 Waist circumference;Weight; LIHC cis rs10791097 0.694 rs2155751 chr11:130755240 G/A cg09137382 chr11:130731461 NA 0.41 6.05 0.31 3.79e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg14393609 chr7:65229607 NA 0.41 6.9 0.35 2.5e-11 Calcium levels; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg20703375 chr7:98957328 ARPC1A 0.41 6.15 0.32 2.15e-9 Longevity; LIHC cis rs6701037 0.566 rs10489326 chr1:175134677 A/G cg00958927 chr1:175162553 KIAA0040 0.39 6.55 0.33 2.11e-10 Alcohol dependence; LIHC trans rs877282 1.000 rs877282 chr10:771532 G/A cg22713356 chr15:30763199 NA 1.41 12.89 0.57 3.01e-31 Uric acid levels; LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs4925386 0.840 rs8124907 chr20:60913127 A/G cg24112000 chr20:60950667 NA -0.49 -6.73 -0.34 7.3e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7086627 0.515 rs10887905 chr10:82210855 A/T cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs6594499 0.872 rs10050834 chr5:110427328 C/T cg04022379 chr5:110408740 TSLP 0.52 8.74 0.43 1.07e-16 Allergic disease (asthma, hay fever or eczema); LIHC cis rs933688 1.000 rs10073935 chr5:90742188 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 21.11 0.75 6.65e-64 Smoking behavior; LIHC cis rs763121 0.853 rs5757253 chr22:39104320 C/T cg21395723 chr22:39101663 GTPBP1 0.4 6.65 0.34 1.15e-10 Menopause (age at onset); LIHC cis rs7487075 0.780 rs12307969 chr12:46759057 G/C cg21428710 chr12:47219797 SLC38A4 0.28 5.76 0.3 1.83e-8 Itch intensity from mosquito bite; LIHC cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs7520050 0.966 rs6680380 chr1:46300189 T/G cg03146154 chr1:46216737 IPP -0.4 -6.54 -0.33 2.27e-10 Red blood cell count;Reticulocyte count; LIHC cis rs34779708 0.833 rs12777517 chr10:35473927 T/G cg03585969 chr10:35415529 CREM 0.87 13.09 0.58 4.92e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs72829446 0.530 rs3853820 chr17:7396781 A/T cg02795151 chr17:7402630 POLR2A 0.51 5.8 0.3 1.49e-8 Androgen levels; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg07677032 chr17:61819896 STRADA 0.43 6.2 0.32 1.62e-9 Prudent dietary pattern; LIHC cis rs950169 0.840 rs4842854 chr15:84942339 T/G cg17507749 chr15:85114479 UBE2QP1 0.74 8.65 0.42 2.04e-16 Schizophrenia; LIHC cis rs7937890 0.531 rs2575859 chr11:14510736 C/T cg02886208 chr11:14281011 SPON1 -0.44 -6.17 -0.32 1.92e-9 Mitochondrial DNA levels; LIHC cis rs6952808 0.630 rs1860832 chr7:2161849 G/A cg02951883 chr7:2050386 MAD1L1 -0.65 -10.58 -0.5 7.83e-23 Bipolar disorder and schizophrenia; LIHC cis rs11098699 0.821 rs2083935 chr4:124214338 A/C cg09941581 chr4:124220074 SPATA5 0.33 6.66 0.34 1.1e-10 Mosquito bite size; LIHC cis rs11628318 0.802 rs6575926 chr14:103050183 G/A cg23461800 chr14:103021989 NA -0.54 -7.53 -0.38 4.42e-13 Platelet count; LIHC cis rs7312774 0.881 rs7297923 chr12:107305573 T/C cg16260113 chr12:107380972 MTERFD3 0.78 10.19 0.48 1.8e-21 Severe influenza A (H1N1) infection; LIHC cis rs4555082 0.874 rs11622166 chr14:105759763 C/A cg06808227 chr14:105710500 BRF1 -0.49 -6.03 -0.31 4.33e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs561341 0.843 rs2028067 chr17:30239698 T/C cg12193833 chr17:30244370 NA -0.51 -5.93 -0.31 7.47e-9 Hip circumference adjusted for BMI; LIHC cis rs59698941 0.765 rs66822519 chr5:132167742 C/T cg02081065 chr5:132209139 LEAP2 0.3 6.37 0.33 6.09e-10 Apolipoprotein A-IV levels; LIHC cis rs12142240 0.698 rs41293273 chr1:46806393 T/C cg00530320 chr1:46809349 NSUN4 0.54 5.8 0.3 1.55e-8 Menopause (age at onset); LIHC cis rs1008375 1.000 rs55939327 chr4:17642937 T/A cg02297831 chr4:17616191 MED28 0.49 7.79 0.39 7.98e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs10411161 1.000 rs10402727 chr19:52370379 C/T cg22319618 chr22:45562946 NUP50 -0.51 -6.83 -0.35 3.78e-11 Breast cancer; LIHC cis rs11098499 0.866 rs7665125 chr4:120402079 G/T cg09307838 chr4:120376055 NA 0.69 11.23 0.52 4.16e-25 Corneal astigmatism; LIHC trans rs7721647 0.853 rs6452960 chr5:90881388 A/G cg11567849 chr6:111751012 REV3L -0.51 -6.14 -0.32 2.34e-9 Breast cancer; LIHC cis rs933688 1.000 rs12655973 chr5:90736537 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.91 17.5 0.69 1.94e-49 Smoking behavior; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg12880250 chr17:43210016 ACBD4;PLCD3 -0.49 -6.64 -0.34 1.22e-10 Systolic blood pressure; LIHC cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg18279126 chr7:2041391 MAD1L1 0.38 6.47 0.33 3.44e-10 Bipolar disorder and schizophrenia; LIHC trans rs875971 0.964 rs60193905 chr7:65971260 A/G cg10756647 chr7:56101905 PSPH 0.44 6.43 0.33 4.18e-10 Aortic root size; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg06873352 chr17:61820015 STRADA 0.74 13.56 0.59 8.39e-34 Prudent dietary pattern; LIHC cis rs1865760 1.000 rs12209482 chr6:25909229 T/G cg17691542 chr6:26056736 HIST1H1C 0.41 6.09 0.31 3.04e-9 Height; LIHC cis rs79149102 0.579 rs73438569 chr15:75354486 T/A cg16226627 chr15:75307476 SCAMP5 0.5 8.72 0.43 1.24e-16 Lung cancer; LIHC cis rs1499280 1.000 rs2548498 chr5:52072645 T/A cg21153758 chr5:52083992 ITGA1;PELO 0.71 6.33 0.32 7.88e-10 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs17666538 0.535 rs4338080 chr8:615598 A/G cg23958373 chr8:599963 NA 0.75 5.77 0.3 1.79e-8 IgG glycosylation; LIHC cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg00166722 chr3:10149974 C3orf24 0.54 6.25 0.32 1.21e-9 Alzheimer's disease; LIHC cis rs6582630 0.519 rs7305570 chr12:38349285 G/A cg26384229 chr12:38710491 ALG10B 0.6 8.28 0.41 2.76e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs17496827 0.780 rs6757951 chr2:223355051 A/G cg25565276 chr2:223520875 FARSB 0.43 6.26 0.32 1.13e-9 Anorexia nervosa; LIHC cis rs5769765 0.542 rs5770725 chr22:50256309 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.58 5.81 0.3 1.44e-8 Schizophrenia; LIHC trans rs1875517 0.510 rs11721241 chr3:117329656 A/C cg17064520 chr10:98591758 LCOR -0.46 -7.1 -0.36 7.28e-12 Waist circumference; LIHC cis rs7131987 0.874 rs10843366 chr12:29407903 T/C cg00204748 chr12:29376779 FAR2 0.42 7.89 0.39 4.23e-14 QT interval; LIHC cis rs2637266 0.967 rs12244619 chr10:78352502 C/T cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs8053891 0.756 rs9930930 chr16:72001971 A/G cg01557791 chr16:72042693 DHODH -0.47 -6.92 -0.35 2.18e-11 Coronary artery disease; LIHC cis rs9640161 0.617 rs56019796 chr7:150009226 T/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.39 -0.41 1.33e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs6545883 0.826 rs777593 chr2:61419103 C/A cg14146966 chr2:61757674 XPO1 0.42 6.91 0.35 2.39e-11 Tuberculosis; LIHC cis rs7107174 1.000 rs2511169 chr11:77965321 T/C cg02023728 chr11:77925099 USP35 0.45 8.57 0.42 3.73e-16 Testicular germ cell tumor; LIHC cis rs67460515 0.563 rs1585481 chr3:160901481 C/T cg17135325 chr3:160939158 NMD3 0.6 8.94 0.44 2.51e-17 Parkinson's disease; LIHC cis rs2637266 1.000 rs7476937 chr10:78357692 A/T cg18941641 chr10:78392320 NA 0.29 6.14 0.32 2.31e-9 Pulmonary function; LIHC cis rs875971 0.862 rs11769079 chr7:65842128 G/A cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs7520050 0.807 rs4274104 chr1:46217941 T/C cg24296786 chr1:45957014 TESK2 -0.4 -5.88 -0.3 9.62e-9 Red blood cell count;Reticulocyte count; LIHC trans rs1945213 0.694 rs1384099 chr11:55866040 A/C cg15704280 chr7:45808275 SEPT13 0.62 8.11 0.4 8.95e-15 Acute lymphoblastic leukemia (childhood); LIHC cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg03806693 chr22:41940476 POLR3H 0.98 10.47 0.49 1.98e-22 Vitiligo; LIHC cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg00091569 chr3:40428383 ENTPD3 -0.39 -6.59 -0.34 1.62e-10 Renal cell carcinoma; LIHC trans rs11724903 0.935 rs938526 chr4:183213736 T/C cg16239906 chr20:35724590 RBL1 -0.64 -6.21 -0.32 1.53e-9 Smoking initiation; LIHC cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg19729930 chr2:74357872 NA -0.78 -16.44 -0.66 3.69e-45 Gestational age at birth (maternal effect); LIHC cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg03806693 chr22:41940476 POLR3H 0.99 10.62 0.5 5.86e-23 Crohn's disease;Inflammatory bowel disease; LIHC cis rs7197653 0.748 rs61460037 chr16:68336125 A/C cg05110241 chr16:68378359 PRMT7 -0.96 -10.28 -0.49 9.02e-22 Magnesium levels; LIHC cis rs765787 0.530 rs4270107 chr15:45535350 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs4638749 0.677 rs12329189 chr2:108812855 T/C cg25838818 chr2:108905173 SULT1C2 -0.4 -6.98 -0.35 1.53e-11 Blood pressure; LIHC cis rs9640161 0.830 rs76741564 chr7:150059529 A/T cg21361702 chr7:150065534 REPIN1 0.53 7.58 0.38 3.23e-13 Blood protein levels;Circulating chemerin levels; LIHC trans rs12478296 1.000 rs6739247 chr2:243039189 C/A cg01596870 chr19:55963115 NA -0.63 -8.27 -0.41 2.94e-15 Obesity-related traits; LIHC cis rs801193 0.660 rs2659914 chr7:66156914 C/T cg12463550 chr7:65579703 CRCP 0.4 5.78 0.3 1.72e-8 Aortic root size; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg04709771 chr16:646395 RAB40C 0.45 8.53 0.42 4.96e-16 Height; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg13395646 chr4:1353034 KIAA1530 -0.44 -6.32 -0.32 8.22e-10 Longevity; LIHC cis rs2304069 0.545 rs7728248 chr5:149394965 A/G cg12661370 chr5:149340060 SLC26A2 0.54 8.06 0.4 1.28e-14 HIV-1 control; LIHC cis rs9486719 0.843 rs2472875 chr6:96844691 G/A cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs1577917 0.958 rs36035797 chr6:86562880 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.22 -0.41 4.25e-15 Response to antipsychotic treatment; LIHC cis rs8114671 0.869 rs2038503 chr20:33675900 G/A cg07148914 chr20:33460835 GGT7 -0.54 -8.18 -0.4 5.79e-15 Height; LIHC cis rs2257205 0.667 rs11651859 chr17:56731926 G/T cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs10504073 0.647 rs4873096 chr8:49995201 A/G cg00325661 chr8:49890786 NA 0.33 7.65 0.38 2.1e-13 Blood metabolite ratios; LIHC cis rs1816752 1.000 rs7999554 chr13:25009769 C/A cg22771759 chr13:24902376 NA 0.33 6.69 0.34 9.16e-11 Obesity-related traits; LIHC cis rs10791097 0.667 rs2155358 chr11:130740357 T/C cg09137382 chr11:130731461 NA 0.41 6.09 0.31 2.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs9929218 1.000 rs12599517 chr16:68814590 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs644799 1.000 rs518919 chr11:95623313 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.13 0.66 6.23e-44 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs765787 0.530 rs11636395 chr15:45535684 G/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.46 -0.37 7.2e-13 Uric acid levels; LIHC cis rs595982 0.559 rs17272680 chr19:49364511 A/G cg15549821 chr19:49342101 PLEKHA4 0.61 6.06 0.31 3.6e-9 Red cell distribution width; LIHC cis rs910316 0.726 rs175040 chr14:75469555 A/G cg11812906 chr14:75593930 NEK9 -0.73 -13.76 -0.6 1.43e-34 Height; LIHC cis rs1639906 0.893 rs13233298 chr7:2227707 C/T cg02951883 chr7:2050386 MAD1L1 -0.54 -7.7 -0.38 1.46e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs55665837 0.540 rs10219313 chr11:14749849 C/T cg25251204 chr11:14927456 NA 0.4 5.74 0.3 2.11e-8 Vitamin D levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg03571073 chr13:113464332 ATP11A 0.38 6.06 0.31 3.51e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs11148252 0.840 rs4369550 chr13:52744910 A/G cg00495681 chr13:53174319 NA 0.41 6.57 0.33 1.82e-10 Lewy body disease; LIHC cis rs763121 0.853 rs138705 chr22:39133803 C/T cg06544989 chr22:39130855 UNC84B 0.39 6.25 0.32 1.25e-9 Menopause (age at onset); LIHC cis rs3008870 1.000 rs12041926 chr1:67434602 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.9 15.38 0.64 6.04e-41 Lymphocyte percentage of white cells; LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg04234412 chr22:24373322 LOC391322 -0.68 -10.15 -0.48 2.5e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs4927850 1.000 rs7627706 chr3:195753353 A/C cg16724585 chr3:197361211 NA -0.46 -6.44 -0.33 4.17e-10 Pancreatic cancer; LIHC cis rs2629540 0.806 rs10901812 chr10:126419384 A/G cg20435097 chr10:126320824 FAM53B 0.43 6.57 0.33 1.9e-10 Cocaine dependence; LIHC cis rs11690935 0.694 rs312921 chr2:172567225 T/C cg13550731 chr2:172543902 DYNC1I2 -0.92 -18.0 -0.7 2e-51 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg24847996 chr12:123340818 HIP1R 0.42 6.45 0.33 3.72e-10 Longevity; LIHC cis rs910316 0.967 rs4899549 chr14:75647494 G/A cg08847533 chr14:75593920 NEK9 -0.85 -17.47 -0.69 2.6e-49 Height; LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.4 0.81 1.03e-80 Prudent dietary pattern; LIHC cis rs7249142 0.549 rs741706 chr19:19281672 C/T cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.21 -0.32 1.56e-9 IgG glycosylation; LIHC cis rs9341808 0.754 rs3793000 chr6:80995137 G/A cg08355045 chr6:80787529 NA 0.32 6.6 0.34 1.61e-10 Sitting height ratio; LIHC cis rs6570726 0.791 rs418701 chr6:145889992 C/T cg23711669 chr6:146136114 FBXO30 0.72 12.85 0.57 4.31e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs826838 0.754 rs2387920 chr12:38626351 A/G cg26384229 chr12:38710491 ALG10B 0.98 12.83 0.57 4.89e-31 Heart rate; LIHC cis rs1401999 0.674 rs562 chr3:183637845 T/C cg20387954 chr3:183756860 HTR3D 0.25 5.75 0.3 1.95e-8 Anterior chamber depth; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 25.23 0.81 4.45e-80 Prudent dietary pattern; LIHC cis rs826838 0.935 rs1843639 chr12:39178919 C/A cg13010199 chr12:38710504 ALG10B 0.5 6.04 0.31 4.04e-9 Heart rate; LIHC cis rs921968 0.643 rs552882 chr2:219401726 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.44 0.33 4.12e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs8044995 0.563 rs55968019 chr16:68398111 G/A cg05110241 chr16:68378359 PRMT7 -0.82 -9.4 -0.45 8.03e-19 Schizophrenia; LIHC cis rs769267 0.930 rs4808957 chr19:19567248 A/G cg03709012 chr19:19516395 GATAD2A 1.02 18.35 0.7 7.4e-53 Tonsillectomy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg25907053 chr2:70369816 NA 0.44 6.16 0.32 2.07e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1385374 0.920 rs34785537 chr12:129273094 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.61 7.42 0.37 9.59e-13 Systemic lupus erythematosus; LIHC cis rs35883536 0.868 rs2484535 chr1:101107748 C/T cg14515779 chr1:101123966 NA 0.64 12.18 0.55 1.36e-28 Monocyte count; LIHC cis rs3791556 1.000 rs3791558 chr2:240113255 G/A cg03281426 chr2:240109471 HDAC4 0.41 6.18 0.32 1.85e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs16866061 1.000 rs72974263 chr2:225447371 C/T cg12698349 chr2:225449008 CUL3 0.8 14.23 0.61 1.96e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs1707322 1.000 rs11211237 chr1:46447329 G/C cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs921968 0.541 rs523937 chr2:219437596 G/C cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.63e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2710642 0.925 rs72807578 chr2:63008044 G/A cg17519650 chr2:63277830 OTX1 -0.57 -8.78 -0.43 8.15e-17 LDL cholesterol levels;LDL cholesterol; LIHC cis rs780096 0.546 rs1060525 chr2:27635582 A/G cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.84 -0.3 1.2e-8 Total body bone mineral density; LIHC cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.3 -0.32 9.1e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6691722 0.506 rs1016209 chr1:24745615 A/G cg18323236 chr1:24743029 NIPAL3 -0.39 -7.39 -0.37 1.15e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs853679 0.517 rs9393891 chr6:28079160 C/T cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs6089584 1.000 rs6089587 chr20:60564829 C/T cg13770153 chr20:60521292 NA -0.35 -6.9 -0.35 2.53e-11 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10950050 chr1:62902319 USP1 0.47 6.85 0.35 3.5e-11 Lung function (FEV1/FVC); LIHC cis rs2836950 0.545 rs11701805 chr21:40618683 T/C cg11890956 chr21:40555474 PSMG1 -0.48 -7.72 -0.39 1.31e-13 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04904834 chr1:179851103 TOR1AIP1 0.44 6.08 0.31 3.14e-9 Pancreatic cancer; LIHC cis rs1003719 0.667 rs13050226 chr21:38457708 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.55 6.44 0.33 4.07e-10 Eye color traits; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg15734942 chr2:242617028 DTYMK 0.38 6.11 0.31 2.76e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2380220 0.872 rs7750757 chr6:95997118 A/G cg04719120 chr6:96025338 MANEA 0.61 6.79 0.34 5.04e-11 Behavioural disinhibition (generation interaction); LIHC cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg06873352 chr17:61820015 STRADA 0.52 7.69 0.38 1.56e-13 Height; LIHC cis rs763014 0.966 rs12935215 chr16:670605 T/C cg00802000 chr16:706648 WDR90 -0.38 -6.22 -0.32 1.49e-9 Height; LIHC cis rs7598759 0.527 rs12987949 chr2:232367511 A/G cg19187155 chr2:232395269 NMUR1 0.59 8.93 0.43 2.66e-17 Noise-induced hearing loss; LIHC cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg24101359 chr6:42928495 GNMT 0.43 5.86 0.3 1.09e-8 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7188697 0.922 rs2090727 chr16:58604161 A/G cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs7937890 1.000 rs6486190 chr11:14401216 A/C cg23387056 chr11:14280742 SPON1 -0.43 -5.99 -0.31 5.38e-9 Mitochondrial DNA levels; LIHC cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs7666738 0.830 rs13134216 chr4:98919765 C/T cg05340658 chr4:99064831 C4orf37 0.65 12.08 0.55 3.19e-28 Colonoscopy-negative controls vs population controls; LIHC trans rs2537594 0.936 rs1404418 chr7:17814085 A/T cg02048674 chr19:49991517 RPL13AP5;RPL13A 0.41 6.06 0.31 3.63e-9 Mean corpuscular hemoglobin; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.59 9.15 0.44 5.38e-18 Height; LIHC cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs611744 0.752 rs609197 chr8:109234035 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs3736485 0.868 rs60060794 chr15:51937181 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -5.94 -0.31 7.08e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4742903 1.000 rs10820603 chr9:106877939 G/A cg14250997 chr9:106856677 SMC2 0.39 6.8 0.35 4.54e-11 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2243480 0.522 rs778717 chr7:65848151 G/C cg07424592 chr7:64974309 NA 0.8 8.33 0.41 2.02e-15 Diabetic kidney disease; LIHC cis rs3749237 0.615 rs6792911 chr3:49429856 C/T cg07636037 chr3:49044803 WDR6 0.52 7.74 0.39 1.16e-13 Resting heart rate; LIHC cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.29 -5.93 -0.31 7.49e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs17818399 0.612 rs4952834 chr2:46777462 C/G cg02822958 chr2:46747628 ATP6V1E2 0.52 8.11 0.4 9.01e-15 Height; LIHC cis rs9790314 1.000 rs1478565 chr3:161027464 C/T cg04691961 chr3:161091175 C3orf57 -0.4 -6.35 -0.32 6.7e-10 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs7945705 0.902 rs10769979 chr11:9010659 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.4 6.57 0.33 1.83e-10 Hemoglobin concentration; LIHC cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.54 -0.59 9.53e-34 Vitiligo; LIHC cis rs2153535 0.601 rs2015281 chr6:8539673 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.33 0.41 2.02e-15 Motion sickness; LIHC cis rs8180040 0.726 rs6785790 chr3:47146932 C/T cg16586182 chr3:47516702 SCAP -0.51 -9.23 -0.45 2.81e-18 Colorectal cancer; LIHC cis rs11105298 0.891 rs10777163 chr12:89830720 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.58 -6.56 -0.33 1.95e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg24531977 chr5:56204891 C5orf35 -0.68 -9.88 -0.47 2e-20 Initial pursuit acceleration; LIHC cis rs7116495 0.867 rs674688 chr11:71578499 A/T cg26138937 chr11:71823887 C11orf51 -0.7 -7.06 -0.36 9.27e-12 Severe influenza A (H1N1) infection; LIHC cis rs763014 0.932 rs35067229 chr16:649638 T/C cg27189623 chr16:705930 WDR90 0.35 5.89 0.3 9.35e-9 Height; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg16517021 chr16:11945358 RSL1D1 -0.41 -6.21 -0.32 1.53e-9 Alopecia areata; LIHC cis rs796364 0.806 rs11694236 chr2:200916230 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs67311347 0.506 rs55962832 chr3:40244451 T/C cg18306943 chr3:40428807 ENTPD3 0.38 6.4 0.33 5.22e-10 Renal cell carcinoma; LIHC cis rs11098499 0.955 rs7685268 chr4:120162188 G/A cg09307838 chr4:120376055 NA 0.75 11.01 0.51 2.56e-24 Corneal astigmatism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19050596 chr2:191879164 STAT1 0.41 6.35 0.32 6.87e-10 Cognitive function; LIHC cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg18252515 chr7:66147081 NA -1.26 -16.63 -0.67 6.04e-46 Diabetic kidney disease; LIHC cis rs9309473 1.000 rs13431267 chr2:73782200 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.56 -0.33 1.97e-10 Metabolite levels; LIHC cis rs3741798 1.000 rs78028836 chr12:12485448 G/A cg08615371 chr12:12503544 MANSC1 0.99 7.88 0.39 4.4e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs1552244 0.554 rs17050705 chr3:10046398 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC cis rs208515 0.525 rs10755508 chr6:66675790 T/C cg07460842 chr6:66804631 NA 0.76 8.85 0.43 4.72e-17 Exhaled nitric oxide levels; LIHC cis rs7503807 0.967 rs9915162 chr17:78614326 T/C cg09596252 chr17:78655493 RPTOR 0.4 7.07 0.36 9.04e-12 Obesity; LIHC cis rs17539620 0.628 rs62432730 chr6:154830717 G/A cg20019720 chr6:154832845 CNKSR3 0.44 6.54 0.33 2.31e-10 Lipoprotein (a) levels; LIHC cis rs3770081 1.000 rs76081054 chr2:86285037 T/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.57 8.8 0.43 7.13e-17 Facial emotion recognition (sad faces); LIHC cis rs1866706 1.000 rs1866707 chr11:12868119 A/G cg25843174 chr11:12811716 TEAD1 -0.3 -6.41 -0.33 4.74e-10 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.716 rs1946650 chr15:76848463 T/C cg03037974 chr15:76606532 NA 0.79 16.05 0.66 1.36e-43 Blood metabolite levels; LIHC cis rs9309473 0.583 rs35885918 chr2:73612234 T/C cg20560298 chr2:73613845 ALMS1 -0.48 -7.67 -0.38 1.85e-13 Metabolite levels; LIHC cis rs709400 0.859 rs7693 chr14:104023704 C/T cg26031613 chr14:104095156 KLC1 1.1 14.05 0.61 1.01e-35 Body mass index; LIHC cis rs9303401 0.659 rs35539277 chr17:56853833 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.95 12.83 0.57 4.91e-31 Cognitive test performance; LIHC cis rs2841277 0.738 rs1036713 chr14:105396693 C/G cg21017887 chr14:105400489 NA -0.61 -10.07 -0.48 4.81e-21 Rheumatoid arthritis; LIHC cis rs748404 0.578 rs2584701 chr15:43684939 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.54 9.5 0.46 3.85e-19 Lung cancer; LIHC cis rs1348850 0.668 rs6734426 chr2:178493770 C/T cg27490568 chr2:178487706 NA 0.68 9.02 0.44 1.38e-17 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs11864453 0.578 rs2072141 chr16:72133211 G/A cg16558253 chr16:72132732 DHX38 -0.41 -6.6 -0.34 1.61e-10 Fibrinogen levels; LIHC cis rs2836950 0.585 rs1029004 chr21:40615343 A/G cg11890956 chr21:40555474 PSMG1 -0.45 -7.31 -0.37 1.89e-12 Menarche (age at onset); LIHC cis rs2282526 0.587 rs91424 chr21:44921161 A/G cg04455712 chr21:45112962 RRP1B -0.45 -7.13 -0.36 5.92e-12 Mean corpuscular hemoglobin; LIHC cis rs4586057 0.514 rs11186351 chr10:92649784 T/C cg14313238 chr10:92632228 RPP30 0.37 6.22 0.32 1.45e-9 Economic and political preferences (time); LIHC cis rs2760061 0.583 rs708124 chr1:228220771 A/T cg01200585 chr1:228362443 C1orf69 0.55 8.47 0.42 7.28e-16 Diastolic blood pressure; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg09976989 chr12:29534158 ERGIC2 -0.48 -6.14 -0.32 2.3e-9 Systolic blood pressure; LIHC cis rs12477438 0.765 rs10181422 chr2:99558970 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.48 -0.38 6.16e-13 Chronic sinus infection; LIHC cis rs4843747 0.671 rs72818540 chr16:88078988 C/T cg06050784 chr16:88016603 BANP 0.4 7.02 0.35 1.22e-11 Menopause (age at onset); LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg12334488 chr2:20871173 GDF7 -0.44 -8.36 -0.41 1.61e-15 Abdominal aortic aneurysm; LIHC cis rs58688157 0.924 rs35865896 chr11:584591 A/G cg01842473 chr11:617407 IRF7;MUPCDH -0.53 -5.72 -0.3 2.38e-8 Systemic lupus erythematosus; LIHC trans rs1005277 0.505 rs7099777 chr10:38183569 A/C cg23533926 chr12:111358616 MYL2 0.33 6.49 0.33 3.07e-10 Extrinsic epigenetic age acceleration; LIHC trans rs9388451 0.626 rs3734637 chr6:126081319 G/T cg05039488 chr6:79577232 IRAK1BP1 -0.65 -10.75 -0.5 2.0500000000000001e-23 Brugada syndrome; LIHC trans rs1005277 0.522 rs289647 chr10:37968278 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.41 0.33 4.89e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6748734 0.894 rs4675869 chr2:241827696 A/G cg20140201 chr2:241835670 C2orf54 -0.47 -6.45 -0.33 3.9e-10 Urinary metabolites; LIHC cis rs1707322 0.721 rs10789468 chr1:46124558 A/G cg06784218 chr1:46089804 CCDC17 0.4 7.46 0.37 7.02e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6088590 0.687 rs13044899 chr20:33287078 G/A cg24642439 chr20:33292090 TP53INP2 0.55 7.73 0.39 1.18e-13 Coronary artery disease; LIHC cis rs7945705 0.902 rs10743093 chr11:8869129 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.44 7.19 0.36 4.14e-12 Hemoglobin concentration; LIHC cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg23758822 chr17:41437982 NA 0.93 17.45 0.69 3.28e-49 Menopause (age at onset); LIHC cis rs644799 1.000 rs693364 chr11:95621926 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.63 8.6 0.42 2.83e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2066819 0.892 rs2066807 chr12:56740682 C/G cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs10508774 1.000 rs58339739 chr10:32909634 G/C cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9393692 0.905 rs2393592 chr6:26285560 A/G cg13736514 chr6:26305472 NA -0.4 -6.63 -0.34 1.28e-10 Educational attainment; LIHC cis rs4638749 0.677 rs2219082 chr2:108854182 C/A cg06795125 chr2:108905320 SULT1C2 -0.31 -6.29 -0.32 9.8e-10 Blood pressure; LIHC cis rs2070488 0.965 rs2284819 chr3:38557161 C/T cg24069376 chr3:38537580 EXOG 0.36 6.37 0.33 6.26e-10 Electrocardiographic conduction measures; LIHC cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg25894440 chr7:65020034 NA -0.53 -6.19 -0.32 1.68e-9 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg07424592 chr7:64974309 NA 0.82 9.64 0.46 1.27e-19 Diabetic kidney disease; LIHC cis rs11583043 1.000 rs6660290 chr1:101483512 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.67 -8.51 -0.42 5.63e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs6977660 0.660 rs10253753 chr7:19823032 A/G cg07541023 chr7:19748670 TWISTNB 0.41 6.16 0.32 2.1e-9 Thyroid stimulating hormone; LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg09455208 chr3:40491958 NA -0.41 -8.44 -0.42 9e-16 Renal cell carcinoma; LIHC cis rs6088813 1.000 rs6142370 chr20:33973378 G/A cg14752227 chr20:34000481 UQCC -0.41 -5.83 -0.3 1.25e-8 Height; LIHC cis rs10791097 0.694 rs7106973 chr11:130758113 G/A cg14779329 chr11:130786720 SNX19 0.43 6.5 0.33 2.83e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs798554 0.836 rs798490 chr7:2801542 C/T cg04166393 chr7:2884313 GNA12 0.43 6.1 0.31 2.91e-9 Height; LIHC cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg22633049 chr21:46681294 NA -0.37 -6.36 -0.33 6.37e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7666738 0.645 rs10013290 chr4:99082799 G/A cg05340658 chr4:99064831 C4orf37 0.7 12.44 0.56 1.42e-29 Colonoscopy-negative controls vs population controls; LIHC trans rs875971 0.929 rs778682 chr7:65837934 A/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs11673344 0.796 rs9676450 chr19:37489407 A/G cg27390819 chr19:37464633 NA -0.52 -6.27 -0.32 1.1e-9 Obesity-related traits; LIHC cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg06640241 chr16:89574553 SPG7 0.66 10.65 0.5 4.59e-23 Multiple myeloma (IgH translocation); LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg13409248 chr3:40428643 ENTPD3 -0.5 -8.49 -0.42 6.42e-16 Renal cell carcinoma; LIHC cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg13047869 chr3:10149882 C3orf24 0.51 6.18 0.32 1.82e-9 Alzheimer's disease; LIHC cis rs11252926 0.563 rs10795103 chr10:451849 C/A cg16346588 chr10:242978 ZMYND11 0.38 5.8 0.3 1.53e-8 Psychosis in Alzheimer's disease; LIHC cis rs367615 0.660 rs4632850 chr5:108832883 C/G cg17395555 chr5:108820864 NA 0.4 8.57 0.42 3.51e-16 Colorectal cancer (SNP x SNP interaction); LIHC cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg03264133 chr6:25882463 NA -0.44 -6.77 -0.34 5.62e-11 Height; LIHC cis rs12478296 1.000 rs6732595 chr2:243035338 T/C cg06360820 chr2:242988706 NA -0.83 -11.88 -0.54 1.8e-27 Obesity-related traits; LIHC cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg07061783 chr6:25882402 NA -0.62 -8.85 -0.43 4.84e-17 Blood metabolite levels; LIHC cis rs7572733 0.515 rs11891555 chr2:198853540 G/T cg03934865 chr2:198174659 NA 0.48 6.95 0.35 1.9e-11 Dermatomyositis; LIHC cis rs4908768 0.501 rs1463051 chr1:8596893 A/T cg20416874 chr1:8611966 RERE 0.69 15.4 0.64 5.12e-41 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs7534824 0.543 rs10493940 chr1:101377845 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 7.62 0.38 2.45e-13 Refractive astigmatism; LIHC cis rs6860806 0.507 rs2631369 chr5:131705266 G/C cg24060327 chr5:131705240 SLC22A5 0.8 12.63 0.56 2.75e-30 Breast cancer; LIHC cis rs35110281 0.720 rs162374 chr21:44927089 T/C cg21573476 chr21:45109991 RRP1B 0.56 10.48 0.49 1.85e-22 Mean corpuscular volume; LIHC cis rs2839186 0.500 rs13052701 chr21:47660045 A/T cg12516959 chr21:47718080 NA -0.44 -6.73 -0.34 7.06e-11 Testicular germ cell tumor; LIHC cis rs798554 1.000 rs798545 chr7:2762386 C/T cg19717773 chr7:2847554 GNA12 -0.42 -6.74 -0.34 6.65e-11 Height; LIHC cis rs7618501 0.521 rs2352984 chr3:49948728 T/C cg24110177 chr3:50126178 RBM5 -0.56 -8.84 -0.43 5.09e-17 Intelligence (multi-trait analysis); LIHC cis rs763121 0.962 rs909564 chr22:39126508 A/G cg06544989 chr22:39130855 UNC84B 0.35 5.73 0.3 2.18e-8 Menopause (age at onset); LIHC cis rs1401999 0.510 rs2293001 chr3:183700211 C/T cg01324343 chr3:183735012 ABCC5 0.39 6.3 0.32 9.09e-10 Anterior chamber depth; LIHC cis rs748404 0.556 rs10851414 chr15:43433932 G/C cg27015174 chr15:43622946 ADAL;LCMT2 -0.36 -5.84 -0.3 1.21e-8 Lung cancer; LIHC cis rs11711311 1.000 rs9826465 chr3:113432254 G/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.41 7.86 0.39 4.94e-14 IgG glycosylation; LIHC cis rs929354 0.772 rs6954050 chr7:156978554 A/G cg16102536 chr7:156981717 UBE3C 0.36 5.97 0.31 5.98e-9 Body mass index; LIHC cis rs936229 0.861 rs11634474 chr15:75116184 C/G cg14664628 chr15:75095509 CSK -1.01 -20.58 -0.74 8.08e-62 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs11098499 0.863 rs13149407 chr4:120437825 A/G cg09307838 chr4:120376055 NA 0.77 11.69 0.53 8.39e-27 Corneal astigmatism; LIHC cis rs9549367 0.789 rs912012 chr13:113886152 G/A cg00898013 chr13:113819073 PROZ -0.42 -7.31 -0.37 1.86e-12 Platelet distribution width; LIHC cis rs9911578 1.000 rs12453459 chr17:56624291 C/T cg05425664 chr17:57184151 TRIM37 0.58 8.65 0.42 1.97e-16 Intelligence (multi-trait analysis); LIHC cis rs240764 0.658 rs11155635 chr6:101199367 C/T cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.34e-9 Neuroticism; LIHC cis rs950169 0.580 rs1061737 chr15:85183790 G/C cg03959625 chr15:84868606 LOC388152 0.45 6.11 0.31 2.69e-9 Schizophrenia; LIHC cis rs7918232 0.556 rs788209 chr10:27434716 G/T cg14442939 chr10:27389572 ANKRD26 0.74 6.08 0.31 3.21e-9 Breast cancer; LIHC cis rs4474465 0.850 rs11237537 chr11:78248397 C/T cg02023728 chr11:77925099 USP35 0.33 5.98 0.31 5.49e-9 Alzheimer's disease (survival time); LIHC cis rs9326248 0.501 rs4938351 chr11:117022352 A/C cg11861562 chr11:117069780 TAGLN 0.37 5.98 0.31 5.49e-9 Blood protein levels; LIHC cis rs12477438 0.765 rs13406288 chr2:99589585 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.5 -8.24 -0.41 3.77e-15 Chronic sinus infection; LIHC cis rs7666738 0.515 rs11733968 chr4:98906448 A/C cg05340658 chr4:99064831 C4orf37 -0.51 -6.95 -0.35 1.82e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs655641 1.000 rs9804630 chr11:85766582 A/G cg09030501 chr11:85779252 PICALM -0.51 -6.16 -0.32 2.03e-9 Platelet count; LIHC trans rs10411161 0.810 rs8102738 chr19:52388229 T/C cg22319618 chr22:45562946 NUP50 -0.64 -7.58 -0.38 3.31e-13 Breast cancer; LIHC cis rs548181 0.577 rs569766 chr11:125532369 G/A cg03464685 chr11:125439445 EI24 0.88 9.76 0.47 5.06e-20 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6450176 1.000 rs67473746 chr5:53296730 G/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs57590327 0.527 rs7610703 chr3:81613942 G/A cg07356753 chr3:81810745 GBE1 -0.56 -8.52 -0.42 5.33e-16 Extraversion; LIHC cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg11062466 chr8:58055876 NA 0.4 5.91 0.3 8.29e-9 Developmental language disorder (linguistic errors); LIHC cis rs918629 0.530 rs2829 chr5:95258447 T/C cg10483112 chr5:95245456 ELL2 -0.38 -6.99 -0.35 1.47e-11 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12095507 chr14:89290958 TTC8 -0.45 -6.15 -0.32 2.19e-9 Pancreatic cancer; LIHC cis rs6867032 0.695 rs3902820 chr5:2000330 T/A cg26168224 chr5:2018326 NA -0.26 -6.29 -0.32 9.83e-10 Gut microbiome composition (winter); LIHC cis rs896854 0.902 rs896852 chr8:95960886 G/T cg13393036 chr8:95962371 TP53INP1 -0.45 -11.03 -0.51 2.02e-24 Type 2 diabetes; LIHC cis rs77106637 0.932 rs7109082 chr11:72707441 A/C cg03713592 chr11:72463424 ARAP1 0.79 6.96 0.35 1.77e-11 Type 2 diabetes; LIHC cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg11987759 chr7:65425863 GUSB -0.39 -6.15 -0.32 2.13e-9 Calcium levels; LIHC trans rs11098499 0.863 rs6858592 chr4:120458692 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.35 0.45 1.17e-18 Corneal astigmatism; LIHC cis rs7615952 0.604 rs9837847 chr3:125623919 G/A cg05084668 chr3:125655381 ALG1L -0.8 -10.61 -0.5 6.59e-23 Blood pressure (smoking interaction); LIHC cis rs11673344 0.864 rs826322 chr19:37504596 A/G cg27390819 chr19:37464633 NA -0.52 -6.38 -0.33 5.73e-10 Obesity-related traits; LIHC cis rs1043515 1.000 rs1043515 chr17:36922196 C/T cg20826740 chr17:37024042 NA -0.38 -6.33 -0.32 7.68e-10 Height; LIHC cis rs7772486 0.719 rs7753770 chr6:146066161 G/A cg13319975 chr6:146136371 FBXO30 0.4 6.61 0.34 1.46e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4268898 0.636 rs72787371 chr2:24570073 T/A cg06627628 chr2:24431161 ITSN2 -0.74 -9.84 -0.47 2.79e-20 Asthma; LIHC cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg17372223 chr3:52568218 NT5DC2 0.37 6.07 0.31 3.43e-9 Electroencephalogram traits; LIHC cis rs9467773 0.595 rs12525810 chr6:26623511 T/TA cg12826209 chr6:26865740 GUSBL1 0.6 6.11 0.31 2.74e-9 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.857 rs6597961 chr11:976677 T/C cg06064525 chr11:970664 AP2A2 -0.5 -12.47 -0.56 1.14e-29 Alzheimer's disease (late onset); LIHC cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 9.9 0.47 1.7e-20 Platelet count; LIHC trans rs4714291 0.963 rs1923489 chr6:40023088 T/C cg02267698 chr19:7991119 CTXN1 0.39 6.21 0.32 1.51e-9 Strep throat; LIHC cis rs5769765 0.778 rs8137331 chr22:50313358 G/C cg26441486 chr22:50317300 CRELD2 0.37 6.33 0.32 7.71e-10 Schizophrenia; LIHC trans rs61931739 0.517 rs4104182 chr12:34081343 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.8 0.35 4.63e-11 Morning vs. evening chronotype; LIHC trans rs6600671 0.967 rs11249349 chr1:121179169 G/C cg09829573 chr1:144692074 NBPF9 -0.43 -7.95 -0.39 2.76e-14 Hip geometry; LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs9534288 0.797 rs2182482 chr13:46582654 T/A cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs651907 0.535 rs34743741 chr3:101532448 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.68 11.32 0.52 1.84e-25 Colorectal cancer; LIHC trans rs7618501 0.633 rs12485600 chr3:50025530 A/G cg21659725 chr3:3221576 CRBN 0.71 11.58 0.53 2.16e-26 Intelligence (multi-trait analysis); LIHC cis rs644799 1.000 rs472231 chr11:95532166 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.14 0.68 5.59e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs12893668 0.703 rs4906336 chr14:104033265 C/G cg19000871 chr14:103996768 TRMT61A -0.42 -6.8 -0.35 4.73e-11 Reticulocyte count; LIHC cis rs10508774 0.810 rs12416226 chr10:32729405 T/C cg01819863 chr10:32635814 EPC1 0.61 5.87 0.3 1.03e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs783540 0.681 rs1259178 chr15:83271876 T/C cg18393722 chr15:85113863 UBE2QP1 -0.42 -6.6 -0.34 1.58e-10 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21937244 chr14:103406412 CDC42BPB -0.63 -9.01 -0.44 1.51e-17 Lung function (FEV1/FVC); LIHC cis rs8180040 0.701 rs62248439 chr3:46996448 A/G cg27129171 chr3:47204927 SETD2 -0.62 -10.56 -0.5 9.16e-23 Colorectal cancer; LIHC cis rs9399135 0.967 rs3756799 chr6:135341011 A/G cg24558204 chr6:135376177 HBS1L 0.42 6.86 0.35 3.16e-11 Red blood cell count; LIHC cis rs2070433 0.539 rs56157650 chr21:47957959 T/C cg12379764 chr21:47803548 PCNT 0.64 9.97 0.47 9.95e-21 Lymphocyte counts; LIHC cis rs9583531 0.600 rs9521909 chr13:111362170 A/G cg15841412 chr13:111365552 ING1 0.47 5.87 0.3 1.04e-8 Coronary artery disease; LIHC cis rs12702595 0.517 rs10268210 chr7:7262324 A/C cg04827551 chr7:7268805 C1GALT1 0.32 5.82 0.3 1.35e-8 Serum dimethylarginine levels (asymmetric/symetric ratio);Symmetrical dimethylarginine levels; LIHC cis rs7572733 0.534 rs700662 chr2:198668751 T/C cg10820045 chr2:198174542 NA 0.47 7.09 0.36 7.92e-12 Dermatomyositis; LIHC cis rs422249 0.634 rs174617 chr11:61629166 A/G cg27386326 chr11:61587980 NA 0.4 7.16 0.36 4.85e-12 Trans fatty acid levels; LIHC cis rs17401966 0.838 rs12120191 chr1:10345772 A/G cg15208524 chr1:10270712 KIF1B 0.38 6.01 0.31 4.82e-9 Hepatocellular carcinoma; LIHC cis rs6429082 0.967 rs834143 chr1:235626406 C/T cg26050004 chr1:235667680 B3GALNT2 0.39 6.19 0.32 1.7e-9 Adiposity; LIHC cis rs3796352 0.764 rs34872575 chr3:52986277 G/A cg04865290 chr3:52927548 TMEM110 -0.51 -5.89 -0.3 9.01e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2380220 0.808 rs2613554 chr6:95916782 C/A cg04719120 chr6:96025338 MANEA -0.58 -6.24 -0.32 1.33e-9 Behavioural disinhibition (generation interaction); LIHC cis rs7659604 0.517 rs56311153 chr4:122729685 T/C cg19748678 chr4:122722346 EXOSC9 0.67 11.07 0.51 1.47e-24 Type 2 diabetes; LIHC cis rs7582720 0.887 rs72934591 chr2:204019762 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05206910 chr17:80230660 CSNK1D 0.48 6.39 0.33 5.54e-10 Lung function (FEV1/FVC); LIHC cis rs3106136 0.649 rs6532487 chr4:95300493 G/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.91 0.3 8.32e-9 Capecitabine sensitivity; LIHC trans rs1814175 0.529 rs10839396 chr11:49852406 G/T cg03929089 chr4:120376271 NA 0.73 11.01 0.51 2.52e-24 Height; LIHC cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg07636037 chr3:49044803 WDR6 -0.68 -10.18 -0.48 1.94e-21 Menarche (age at onset); LIHC cis rs9303401 0.659 rs35082010 chr17:56936867 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.34 0.56 3.31e-29 Cognitive test performance; LIHC cis rs34779708 0.931 rs35126129 chr10:35452141 G/A cg03585969 chr10:35415529 CREM 0.86 12.87 0.57 3.46e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11608355 0.515 rs2287191 chr12:109931741 C/T cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs1552244 0.626 rs2886396 chr3:10037670 C/T cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg25204440 chr1:209979598 IRF6 0.5 7.8 0.39 7.47e-14 Cleft lip with or without cleft palate; LIHC cis rs9549367 0.789 rs9549705 chr13:113888425 T/C cg18105134 chr13:113819100 PROZ -0.67 -11.68 -0.53 9.4e-27 Platelet distribution width; LIHC cis rs9649465 1.000 rs1073670 chr7:123345029 A/C cg03229431 chr7:123269106 ASB15 -0.38 -8.04 -0.4 1.44e-14 Migraine; LIHC cis rs6542838 0.780 rs981601 chr2:99463882 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.42 -5.83 -0.3 1.27e-8 Fear of minor pain; LIHC cis rs936229 0.668 rs67411922 chr15:75187612 A/G cg10253484 chr15:75165896 SCAMP2 -0.59 -6.93 -0.35 2.17e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs11997175 0.580 rs34398087 chr8:33813800 A/G ch.8.33884649F chr8:33765107 NA -0.4 -6.54 -0.33 2.28e-10 Body mass index; LIHC cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg25072359 chr17:41440525 NA 0.37 5.91 0.3 8.06e-9 Menopause (age at onset); LIHC cis rs10463316 0.894 rs954341 chr5:150751855 G/A cg03212797 chr5:150827313 SLC36A1 -0.46 -7.07 -0.36 8.73e-12 Metabolite levels (Pyroglutamine); LIHC cis rs6840360 0.615 rs56319216 chr4:152463716 C/T cg22705602 chr4:152727874 NA -0.32 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs7223966 1.000 rs7209435 chr17:61712964 T/C cg05941027 chr17:61774174 LIMD2 0.31 6.19 0.32 1.69e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6570726 0.870 rs370653 chr6:145823642 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.86 9.12 0.44 6.63e-18 Platelet count; LIHC cis rs896854 0.517 rs9643353 chr8:95957063 A/G cg23172400 chr8:95962367 TP53INP1 0.34 6.95 0.35 1.89e-11 Type 2 diabetes; LIHC cis rs9783347 1.000 rs10734259 chr11:18314865 A/G cg15585147 chr11:18324498 HPS5 0.45 6.88 0.35 2.92e-11 Pancreatic cancer; LIHC cis rs6977660 1.000 rs6943114 chr7:19818354 G/T cg07541023 chr7:19748670 TWISTNB 0.37 5.83 0.3 1.31e-8 Thyroid stimulating hormone; LIHC cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg05896524 chr21:47604654 C21orf56 0.49 7.86 0.39 5.21e-14 Testicular germ cell tumor; LIHC cis rs950169 0.580 rs11635597 chr15:85165699 C/T cg17507749 chr15:85114479 UBE2QP1 0.69 7.91 0.39 3.59e-14 Schizophrenia; LIHC cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg12311346 chr5:56204834 C5orf35 0.66 8.53 0.42 4.65e-16 Initial pursuit acceleration; LIHC cis rs17106184 1.000 rs12089568 chr1:51406874 G/T cg07174182 chr1:51127561 FAF1 -0.74 -7.94 -0.39 2.99e-14 Type 2 diabetes; LIHC trans rs11098499 0.954 rs10008392 chr4:120318839 G/A cg25214090 chr10:38739885 LOC399744 0.6 9.72 0.47 7.17e-20 Corneal astigmatism; LIHC cis rs1547553 1 rs1547553 chr18:77926197 C/A cg14906638 chr18:78001859 PARD6G -0.76 -9.76 -0.47 5.1e-20 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs9640161 0.659 rs11974980 chr7:150009838 C/T cg10018233 chr7:150070692 REPIN1 0.5 8.19 0.4 5.27e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs36051895 0.626 rs10283563 chr9:5075603 C/T cg02405213 chr9:5042618 JAK2 -0.71 -12.6 -0.56 3.63e-30 Pediatric autoimmune diseases; LIHC cis rs9814567 1.000 rs9828815 chr3:134265749 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC cis rs9297145 0.585 rs62473049 chr7:98777685 T/C cg05967295 chr7:98741636 SMURF1 -0.4 -6.65 -0.34 1.13e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs2732480 0.537 rs1061986 chr12:48736439 T/C cg21466736 chr12:48725269 NA -0.72 -11.03 -0.51 2.11e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.44e-8 Alzheimer's disease; LIHC cis rs765787 0.530 rs1648289 chr15:45516494 A/G cg25801113 chr15:45476975 SHF 0.4 6.82 0.35 4.22e-11 Uric acid levels; LIHC cis rs9309473 1.000 rs7584575 chr2:73666402 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.86 -0.35 3.18e-11 Metabolite levels; LIHC cis rs6952808 0.691 rs2398709 chr7:2112548 C/T cg20295408 chr7:1910781 MAD1L1 -0.4 -5.81 -0.3 1.4e-8 Bipolar disorder and schizophrenia; LIHC cis rs2108622 0.785 rs3093199 chr19:15989871 T/A cg13772218 chr19:15982569 NA 0.35 7.21 0.36 3.62e-12 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs60871478 1.000 rs4719314 chr7:822523 A/G cg04727924 chr7:799746 HEATR2 -0.56 -8.07 -0.4 1.23e-14 Cerebrospinal P-tau181p levels; LIHC cis rs903552 1.000 rs8027380 chr15:102005810 T/C cg00659931 chr15:102010125 PCSK6 -0.46 -6.2 -0.32 1.63e-9 Diabetic kidney disease; LIHC cis rs9916302 0.861 rs4795376 chr17:37669043 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.3 -0.58 8.14e-33 Glomerular filtration rate (creatinine); LIHC cis rs546131 0.600 rs502857 chr11:34854662 A/G cg06937548 chr11:34938143 PDHX;APIP 0.61 8.14 0.4 7.63e-15 Lung disease severity in cystic fibrosis; LIHC cis rs7520050 0.966 rs1707336 chr1:46493460 T/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.86 0.3 1.07e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7208859 0.524 rs8069400 chr17:29075967 G/T cg14067834 chr17:29058358 SUZ12P 0.69 6.87 0.35 3.12e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg19318889 chr4:1322082 MAEA 0.46 7.21 0.36 3.73e-12 Longevity; LIHC cis rs12497850 0.931 rs1134591 chr3:48972892 C/T cg07636037 chr3:49044803 WDR6 0.91 16.66 0.67 4.76e-46 Parkinson's disease; LIHC cis rs3093024 0.595 rs4458654 chr6:167476068 A/C cg23791538 chr6:167370224 RNASET2 -0.52 -7.84 -0.39 5.82e-14 Rheumatoid arthritis; LIHC cis rs13161895 1.000 rs248320 chr5:179432096 G/A cg02702477 chr5:179499311 RNF130 0.75 10.29 0.49 7.91e-22 LDL cholesterol; LIHC cis rs992157 0.835 rs6729058 chr2:219148369 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.16 -0.55 1.57e-28 Colorectal cancer; LIHC cis rs1559088 0.501 rs35492529 chr19:33597495 C/G cg27124370 chr19:33622961 WDR88 0.49 6.91 0.35 2.41e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4555082 1.000 rs7146012 chr14:105757566 G/A cg13114125 chr14:105738426 BRF1 -0.69 -9.27 -0.45 2.21e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs3917254 0.596 rs13001315 chr2:102763210 G/A cg22835712 chr2:102737379 NA -0.5 -5.75 -0.3 1.94e-8 Blood protein levels; LIHC cis rs10861342 0.892 rs3794232 chr12:105615849 C/T cg23923672 chr12:105501055 KIAA1033 0.62 6.95 0.35 1.85e-11 IgG glycosylation; LIHC cis rs6570726 0.846 rs411468 chr6:145832792 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.75 0.3 1.93e-8 Menopause (age at onset); LIHC cis rs1559088 0.512 rs34266236 chr19:33564874 C/A cg27124370 chr19:33622961 WDR88 0.44 5.85 0.3 1.17e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2153535 0.580 rs1335637 chr6:8465101 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC trans rs12310956 0.532 rs10844712 chr12:33961022 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.74 0.34 6.65e-11 Morning vs. evening chronotype; LIHC cis rs2404602 0.967 rs12148805 chr15:76800659 G/A cg03037974 chr15:76606532 NA 0.72 13.83 0.6 7.59e-35 Blood metabolite levels; LIHC cis rs7647973 0.667 rs11721148 chr3:49646669 G/A cg03060546 chr3:49711283 APEH 0.61 6.88 0.35 2.89e-11 Menarche (age at onset); LIHC cis rs5769765 0.955 rs9616368 chr22:50303533 C/G cg26441486 chr22:50317300 CRELD2 0.36 5.84 0.3 1.22e-8 Schizophrenia; LIHC cis rs7027203 0.717 rs7869328 chr9:96588782 A/G cg14598338 chr9:96623480 NA -0.3 -5.95 -0.31 6.63e-9 DNA methylation (variation); LIHC cis rs6456156 0.586 rs12213683 chr6:167460718 G/A cg23791538 chr6:167370224 RNASET2 -0.53 -8.42 -0.41 1.04e-15 Primary biliary cholangitis; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24511375 chr15:75940328 SNX33 -0.49 -6.31 -0.32 8.89e-10 Systolic blood pressure; LIHC cis rs7927592 0.763 rs10896326 chr11:68234571 T/C cg20283391 chr11:68216788 NA -0.38 -6.12 -0.31 2.56e-9 Total body bone mineral density; LIHC cis rs1008375 0.931 rs10019482 chr4:17578079 G/A cg02297831 chr4:17616191 MED28 0.48 7.24 0.36 2.9e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2832191 0.716 rs2249028 chr21:30365322 G/A cg08807101 chr21:30365312 RNF160 0.8 12.33 0.55 3.67e-29 Dental caries; LIHC cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg21280719 chr6:42927975 GNMT -0.32 -7.27 -0.37 2.41e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1499614 1.000 rs2659903 chr7:66180931 G/A cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC trans rs4650994 0.524 rs2811299 chr1:178586377 A/G cg05059571 chr16:84539110 KIAA1609 0.43 7.14 0.36 5.57e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9303401 0.614 rs3087762 chr17:56568680 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.86 11.3 0.52 2.18e-25 Cognitive test performance; LIHC cis rs1355223 0.902 rs1773910 chr11:34741253 G/A cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.35 -0.32 6.72e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg06453172 chr10:134556979 INPP5A -0.65 -9.01 -0.44 1.47e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7395581 0.918 rs3781622 chr11:47348702 T/C cg26139080 chr11:47293733 MADD -0.5 -8.42 -0.41 1.07e-15 HDL cholesterol; LIHC cis rs8180040 0.764 rs12629262 chr3:47196580 C/T cg27129171 chr3:47204927 SETD2 0.69 12.11 0.55 2.57e-28 Colorectal cancer; LIHC cis rs2243480 1.000 rs3885839 chr7:65290403 G/T cg07424592 chr7:64974309 NA 0.81 9.05 0.44 1.13e-17 Diabetic kidney disease; LIHC cis rs9790314 0.663 rs1599379 chr3:160860665 A/G cg03342759 chr3:160939853 NMD3 -0.75 -11.64 -0.53 1.36e-26 Morning vs. evening chronotype; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg23644127 chr8:96037660 C8orf38 -0.4 -6.15 -0.32 2.13e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs9790314 1.000 rs7638668 chr3:161047283 G/A cg04691961 chr3:161091175 C3orf57 -0.42 -6.64 -0.34 1.25e-10 Morning vs. evening chronotype; LIHC cis rs2842992 0.724 rs2273823 chr6:160211485 T/C cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.14 0.44 5.61e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs12477438 0.798 rs2084987 chr2:99587885 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.13 -15.79 -0.65 1.5e-42 Chronic sinus infection; LIHC cis rs11785400 1.000 rs4736342 chr8:143735190 A/G cg24634471 chr8:143751801 JRK 0.53 8.56 0.42 3.93e-16 Schizophrenia; LIHC cis rs2455601 1.000 rs11042114 chr11:8919889 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.47 -6.36 -0.33 6.52e-10 Schizophrenia; LIHC cis rs11792861 0.566 rs67780641 chr9:111850710 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.46 6.61 0.34 1.51e-10 Menarche (age at onset); LIHC cis rs4713118 0.621 rs9368548 chr6:28034737 A/G cg16479474 chr6:28041457 NA 0.48 7.0 0.35 1.34e-11 Parkinson's disease; LIHC cis rs1371867 0.810 rs1692004 chr8:101247320 T/C cg06636551 chr8:101224915 SPAG1 0.5 9.37 0.45 1.03e-18 Atrioventricular conduction; LIHC cis rs2637266 1.000 rs12784382 chr10:78378348 G/T cg18941641 chr10:78392320 NA 0.27 5.72 0.3 2.35e-8 Pulmonary function; LIHC cis rs921968 0.643 rs4674319 chr2:219510320 C/T cg18887096 chr2:219472410 PLCD4 0.36 5.95 0.31 6.61e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.96 22.24 0.77 2.15e-68 Prudent dietary pattern; LIHC cis rs4888262 0.526 rs4888253 chr16:74583146 C/T cg01733217 chr16:74700730 RFWD3 0.79 15.25 0.64 2.04e-40 Testicular germ cell tumor; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg12753518 chr1:28414763 EYA3 -0.56 -6.16 -0.32 2.06e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs970821 1.000 rs13279803 chr8:124750521 C/T cg00283535 chr8:124749564 ANXA13 0.35 6.07 0.31 3.44e-9 Breast cancer; LIHC trans rs7927370 0.510 rs11559578 chr11:54994975 C/A cg03929089 chr4:120376271 NA 0.51 6.26 0.32 1.13e-9 Systemic lupus erythematosus; LIHC cis rs9916302 0.555 rs12940193 chr17:37652178 T/G cg00129232 chr17:37814104 STARD3 -0.42 -6.68 -0.34 9.74e-11 Glomerular filtration rate (creatinine); LIHC cis rs8044995 0.563 rs8059585 chr16:68376811 G/A cg03983715 chr16:68378420 PRMT7 -0.5 -6.12 -0.31 2.49e-9 Schizophrenia; LIHC cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg00684032 chr4:1343700 KIAA1530 0.52 7.59 0.38 3.1e-13 Obesity-related traits; LIHC cis rs11122272 0.701 rs11122273 chr1:231476789 A/G cg06096015 chr1:231504339 EGLN1 0.47 8.85 0.43 4.65e-17 Hemoglobin concentration; LIHC cis rs992157 0.764 rs4552182 chr2:219184872 G/T cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.21 0.48 1.49e-21 Colorectal cancer; LIHC cis rs1401999 0.932 rs4148557 chr3:183733784 A/G cg20387954 chr3:183756860 HTR3D 0.29 6.32 0.32 8.2e-10 Anterior chamber depth; LIHC cis rs2066819 1.000 rs57137641 chr12:56741228 G/A cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs2204008 0.604 rs11172718 chr12:38069819 T/C cg13010199 chr12:38710504 ALG10B 0.47 5.73 0.3 2.18e-8 Bladder cancer; LIHC cis rs2279817 1.000 rs1339801 chr1:18020298 A/G cg21791023 chr1:18019539 ARHGEF10L 0.62 8.68 0.42 1.64e-16 Neuroticism; LIHC cis rs9611565 0.592 rs6519270 chr22:42078666 A/G cg03806693 chr22:41940476 POLR3H 0.81 9.17 0.44 4.47e-18 Vitiligo; LIHC cis rs10540 1.000 rs79440439 chr11:478147 A/C cg03576123 chr11:487126 PTDSS2 -1.24 -8.94 -0.44 2.53e-17 Body mass index; LIHC cis rs5758511 0.514 rs3985938 chr22:42511727 G/T cg20195005 chr22:42527684 CYP2D6 0.32 6.15 0.32 2.19e-9 Birth weight; LIHC cis rs477692 0.612 rs58103386 chr10:131319958 C/A cg19680672 chr10:131412579 MGMT -0.38 -5.8 -0.3 1.49e-8 Response to temozolomide; LIHC cis rs55665837 0.524 rs61884009 chr11:14426462 C/T cg19336497 chr11:14380999 RRAS2 -0.58 -10.68 -0.5 3.66e-23 Vitamin D levels; LIHC cis rs589448 0.902 rs315131 chr12:69761839 T/G cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 9.91e-21 Cerebrospinal fluid biomarker levels; LIHC cis rs74233809 1.000 rs10458729 chr10:104841479 C/T cg03493300 chr10:104813866 CNNM2 0.47 6.27 0.32 1.07e-9 Birth weight; LIHC cis rs924607 1.000 rs924607 chr5:610093 C/T cg04476341 chr5:669733 TPPP -0.4 -9.0 -0.44 1.59e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs950027 0.787 rs2433616 chr15:45728599 A/G cg26924012 chr15:45694286 SPATA5L1 0.61 9.7 0.46 8.02e-20 Response to fenofibrate (adiponectin levels); LIHC cis rs898097 0.841 rs11656358 chr17:80853956 G/A cg15369054 chr17:80825471 TBCD 0.45 6.49 0.33 3e-10 Breast cancer; LIHC cis rs7100689 0.622 rs10887798 chr10:82131613 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.18 0.48 2.03e-21 Post bronchodilator FEV1; LIHC trans rs11098499 0.908 rs7695996 chr4:120322033 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.76 0.47 5.25e-20 Corneal astigmatism; LIHC trans rs9747201 0.962 rs62079995 chr17:80076624 C/T cg07393940 chr7:158741817 NA -0.57 -6.71 -0.34 8.19e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9916302 0.821 rs412430 chr17:37737094 C/G cg07936489 chr17:37558343 FBXL20 -0.84 -13.57 -0.59 7.34e-34 Glomerular filtration rate (creatinine); LIHC cis rs12908161 0.920 rs12904605 chr15:85201419 T/C cg12863693 chr15:85201151 NMB 0.49 6.94 0.35 1.96e-11 Schizophrenia; LIHC cis rs66573146 0.808 rs55942328 chr4:6990960 T/G cg15105060 chr4:7024189 TBC1D14 -0.81 -6.47 -0.33 3.48e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg13699009 chr12:122356056 WDR66 0.61 9.17 0.44 4.62e-18 Mean corpuscular volume; LIHC cis rs2012796 0.785 rs61986597 chr14:81853107 T/C cg23690444 chr14:81902736 NA -0.5 -6.83 -0.35 3.87e-11 Night sleep phenotypes; LIHC cis rs7312933 0.703 rs1059360 chr12:42554505 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 7.9 0.39 3.92e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14694896 chr8:104427370 SLC25A32;DCAF13 -0.54 -6.69 -0.34 9.18e-11 Systolic blood pressure; LIHC cis rs4638749 0.677 rs13398290 chr2:108833853 G/T cg25838818 chr2:108905173 SULT1C2 -0.39 -6.68 -0.34 9.72e-11 Blood pressure; LIHC cis rs1003719 0.715 rs2835658 chr21:38565201 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.31 -0.49 6.91e-22 Eye color traits; LIHC cis rs6912958 0.728 rs6923230 chr6:88213949 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.06 -0.4 1.33e-14 Monocyte percentage of white cells; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg26531923 chr6:24646364 KIAA0319 0.44 6.05 0.31 3.88e-9 Triglycerides; LIHC cis rs8017423 0.647 rs12590712 chr14:90822481 T/C cg04374321 chr14:90722782 PSMC1 -0.49 -7.26 -0.37 2.56e-12 Mortality in heart failure; LIHC cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg13126279 chr21:47581558 C21orf56 -0.42 -6.58 -0.34 1.8e-10 Testicular germ cell tumor; LIHC cis rs870825 0.587 rs35845099 chr4:185639762 A/G cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg25894440 chr7:65020034 NA -0.52 -6.07 -0.31 3.44e-9 Diabetic kidney disease; LIHC cis rs1008375 1.000 rs55939327 chr4:17642937 T/A cg15017067 chr4:17643749 FAM184B 0.34 5.85 0.3 1.14e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs1707322 0.721 rs10157795 chr1:46228192 G/A cg03146154 chr1:46216737 IPP 0.55 9.47 0.46 4.84e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2439831 0.850 rs28476182 chr15:44139643 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.33 0.41 2.02e-15 Lung cancer in ever smokers; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14577476 chr17:49337432 MBTD1;UTP18 -0.46 -6.26 -0.32 1.16e-9 Pancreatic cancer; LIHC cis rs7772486 0.686 rs9497380 chr6:145955305 T/C cg23711669 chr6:146136114 FBXO30 0.63 11.48 0.53 4.91e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs757081 0.667 rs17473243 chr11:17266259 G/A cg15432903 chr11:17409602 KCNJ11 -0.42 -5.81 -0.3 1.41e-8 Systolic blood pressure; LIHC cis rs1552244 0.882 rs13075842 chr3:10055813 A/C cg13047869 chr3:10149882 C3orf24 0.42 5.87 0.3 1.03e-8 Alzheimer's disease; LIHC cis rs77637988 0.578 rs7576964 chr2:48601448 G/T cg00032884 chr2:48540671 FOXN2 0.4 6.34 0.32 7.08e-10 Joint mobility (Beighton score); LIHC cis rs909341 0.909 rs6122158 chr20:62363096 G/A cg03999872 chr20:62272968 STMN3 -0.46 -6.81 -0.35 4.41e-11 Atopic dermatitis; LIHC cis rs4388979 0.929 rs12426673 chr12:109490296 G/T cg03220751 chr12:109490328 USP30 0.86 12.95 0.57 1.81e-31 Plateletcrit;Platelet count; LIHC cis rs7223966 1.000 rs6504170 chr17:61709168 C/T cg05941027 chr17:61774174 LIMD2 0.3 6.03 0.31 4.15e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1419980 0.630 rs2377089 chr12:7737325 T/C cg10578777 chr12:7781093 NA 0.48 8.47 0.42 7.25e-16 HDL cholesterol levels; LIHC cis rs2522056 1.000 rs2706339 chr5:131800105 G/T cg24060327 chr5:131705240 SLC22A5 0.56 7.4 0.37 1.1e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs1185460 1.000 rs1784305 chr11:118942048 G/A cg23280166 chr11:118938394 VPS11 0.61 8.2 0.41 5.02e-15 Coronary artery disease; LIHC cis rs9910055 0.530 rs11652651 chr17:42302907 A/G cg13607699 chr17:42295918 UBTF -0.65 -11.5 -0.53 4.19e-26 Total body bone mineral density; LIHC trans rs668210 0.643 rs549334 chr11:65774659 C/G cg17712092 chr4:129076599 LARP1B 0.59 6.38 0.33 5.83e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs782590 0.582 rs2627767 chr2:55926815 A/T cg18811423 chr2:55921094 PNPT1 0.77 11.66 0.53 1.11e-26 Metabolic syndrome; LIHC cis rs10540 1.000 rs12801148 chr11:511707 T/G cg03352830 chr11:487213 PTDSS2 0.79 6.39 0.33 5.48e-10 Body mass index; LIHC trans rs11039798 0.764 rs11039771 chr11:48513273 C/T cg15704280 chr7:45808275 SEPT13 0.6 6.12 0.31 2.56e-9 Axial length; LIHC cis rs12477438 0.501 rs17759607 chr2:99737005 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.6 11.19 0.52 5.77e-25 Chronic sinus infection; LIHC cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg09417038 chr21:47716443 C21orf57 -0.47 -7.02 -0.35 1.24e-11 Testicular germ cell tumor; LIHC cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11777782 chr19:18284937 IFI30 0.47 6.72 0.34 7.48e-11 Lung function (FEV1/FVC); LIHC cis rs2932538 0.922 rs12739994 chr1:113131159 T/C cg22162597 chr1:113214053 CAPZA1 0.71 9.42 0.45 6.95e-19 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs722599 0.501 rs10139347 chr14:75390135 T/C cg08847533 chr14:75593920 NEK9 0.6 10.35 0.49 4.91e-22 IgG glycosylation; LIHC cis rs7945705 0.782 rs2742545 chr11:8884308 C/G cg12365402 chr11:9010492 NRIP3 -0.26 -6.65 -0.34 1.17e-10 Hemoglobin concentration; LIHC cis rs970821 0.667 rs6470182 chr8:124751705 T/C cg00283535 chr8:124749564 ANXA13 -0.42 -7.49 -0.38 5.77e-13 Breast cancer; LIHC cis rs4713118 0.513 rs149955 chr6:28036225 G/C cg23485639 chr6:28045615 ZNF165 0.38 5.77 0.3 1.77e-8 Parkinson's disease; LIHC cis rs769267 0.930 rs1865034 chr19:19605763 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.88 0.39 4.52e-14 Tonsillectomy; LIHC cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.66 5.74 0.3 2.1e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6918586 0.658 rs198819 chr6:26124430 C/T cg18357526 chr6:26021779 HIST1H4A -0.57 -8.59 -0.42 3.13e-16 Schizophrenia; LIHC cis rs6840360 0.571 rs28454076 chr4:152520083 G/T cg22705602 chr4:152727874 NA -0.31 -6.2 -0.32 1.63e-9 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs1706831 chr15:45516230 T/C cg24006582 chr15:45444508 DUOX1 -0.53 -7.66 -0.38 1.92e-13 Uric acid levels; LIHC cis rs9942416 0.660 rs111937612 chr5:74979631 C/T cg19683494 chr5:74908142 NA 0.58 7.57 0.38 3.52e-13 Age-related disease endophenotypes; LIHC cis rs3768617 0.510 rs729819 chr1:183109034 G/A ch.1.3577855R chr1:183094577 LAMC1 0.45 6.1 0.31 2.83e-9 Fuchs's corneal dystrophy; LIHC cis rs611744 0.647 rs7016198 chr8:109262752 G/A cg21045802 chr8:109455806 TTC35 0.59 10.51 0.49 1.41e-22 Dupuytren's disease; LIHC cis rs7165170 0.550 rs76750851 chr15:91196201 C/T cg26821196 chr15:91095069 CRTC3 -0.36 -6.71 -0.34 8.33e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs11711311 0.822 rs9850256 chr3:113408382 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.36 -6.67 -0.34 1e-10 IgG glycosylation; LIHC cis rs6879260 1.000 rs7730585 chr5:179733440 T/C cg13944838 chr5:179740914 GFPT2 -0.51 -7.13 -0.36 5.86e-12 Height; LIHC cis rs1059312 0.808 rs10847694 chr12:129292457 C/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.77 -16.85 -0.67 8.58e-47 Systemic lupus erythematosus; LIHC cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg10802521 chr3:52805072 NEK4 -0.45 -7.64 -0.38 2.21e-13 Electroencephalogram traits; LIHC cis rs2404602 0.735 rs11072598 chr15:76764788 T/C cg03037974 chr15:76606532 NA -0.63 -10.9 -0.51 5.92e-24 Blood metabolite levels; LIHC cis rs2991971 0.776 rs12139364 chr1:45890155 T/C cg05343316 chr1:45956843 TESK2 -0.43 -6.35 -0.32 6.84e-10 High light scatter reticulocyte count; LIHC cis rs10504073 0.647 rs9643395 chr8:50014500 A/C cg00325661 chr8:49890786 NA 0.31 7.13 0.36 6.13e-12 Blood metabolite ratios; LIHC trans rs116095464 0.558 rs7730700 chr5:264713 G/A cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs7584330 0.697 rs60278044 chr2:238357118 A/G cg14458575 chr2:238380390 NA 0.47 6.99 0.35 1.42e-11 Prostate cancer; LIHC cis rs79387448 0.745 rs7572284 chr2:103119423 C/A cg09003973 chr2:102972529 NA 0.79 6.89 0.35 2.72e-11 Gut microbiota (bacterial taxa); LIHC cis rs1801251 0.963 rs7591176 chr2:233581803 C/A cg08000102 chr2:233561755 GIGYF2 0.76 11.48 0.53 5.08e-26 Coronary artery disease; LIHC cis rs921968 0.565 rs3755045 chr2:219609162 T/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.97e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs17826219 0.568 rs2626985 chr17:29077437 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.04 0.4 1.48e-14 Body mass index; LIHC cis rs1395 1.000 rs3769143 chr2:27450724 A/G cg23587288 chr2:27483067 SLC30A3 0.31 6.08 0.31 3.29e-9 Blood metabolite levels; LIHC cis rs79387448 0.745 rs57942521 chr2:103139849 A/G cg09003973 chr2:102972529 NA 0.84 6.63 0.34 1.27e-10 Gut microbiota (bacterial taxa); LIHC cis rs9814567 1.000 rs6793487 chr3:134299426 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.41 0.56 1.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7909074 0.766 rs5000415 chr10:45383674 C/T cg04218760 chr10:45406644 TMEM72 -0.24 -7.38 -0.37 1.23e-12 Mean corpuscular volume; LIHC trans rs7618501 0.633 rs11130228 chr3:50003246 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.56 9.23 0.45 2.83e-18 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.643 rs7394524 chr11:933865 T/C cg10932868 chr11:921992 NA 0.38 7.32 0.37 1.83e-12 Alzheimer's disease (late onset); LIHC cis rs1823913 1.000 rs10445782 chr2:192101365 T/C cg12404831 chr2:192114017 MYO1B -0.34 -6.83 -0.35 3.85e-11 Obesity-related traits; LIHC cis rs1023500 0.573 rs133374 chr22:42465941 G/A cg04733989 chr22:42467013 NAGA 0.66 9.69 0.46 9.09e-20 Schizophrenia; LIHC cis rs2412488 1.000 rs10011259 chr4:54285952 A/G cg22241045 chr4:54363911 LNX1 -0.47 -7.51 -0.38 5.16e-13 DNA methylation (variation); LIHC cis rs7223966 1.000 rs16947005 chr17:61702989 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.57 -6.77 -0.34 5.71e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg24675658 chr1:53192096 ZYG11B 0.57 8.99 0.44 1.7e-17 Monocyte count; LIHC trans rs3780486 0.522 rs1328898 chr9:33163271 A/G cg04842962 chr6:43655489 MRPS18A 0.8 15.12 0.63 6.63e-40 IgG glycosylation; LIHC cis rs7607369 0.719 rs690882 chr2:219640620 T/C cg02985541 chr2:219472218 PLCD4 -0.38 -6.58 -0.34 1.8e-10 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs2839186 0.872 rs13046834 chr21:47701485 T/C cg00612595 chr21:47717864 NA -0.36 -5.86 -0.3 1.1e-8 Testicular germ cell tumor; LIHC cis rs1005277 0.589 rs2749624 chr10:38529865 A/G cg25427524 chr10:38739819 LOC399744 -0.74 -14.76 -0.62 1.68e-38 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg06873352 chr17:61820015 STRADA 0.73 13.15 0.58 2.92e-32 Prudent dietary pattern; LIHC cis rs7216064 1.000 rs7216064 chr17:65898809 G/A cg12091567 chr17:66097778 LOC651250 -0.61 -8.62 -0.42 2.61e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9443189 0.570 rs775075 chr6:76380035 A/C cg01950844 chr6:76311363 SENP6 -0.86 -10.58 -0.5 7.87e-23 Prostate cancer; LIHC cis rs2116941 1.000 rs2033493 chr19:10340854 A/C cg01850179 chr19:10340795 S1PR2 -0.58 -9.35 -0.45 1.22e-18 Pulse pressure; LIHC cis rs2836950 0.565 rs2150414 chr21:40614988 A/G cg06238570 chr21:40685208 BRWD1 -0.42 -6.7 -0.34 8.37e-11 Menarche (age at onset); LIHC cis rs6964587 1.000 rs11982213 chr7:91722966 A/G cg17063962 chr7:91808500 NA 1.0 18.85 0.71 7.18e-55 Breast cancer; LIHC cis rs11864453 0.680 rs8047377 chr16:72148339 T/C cg16558253 chr16:72132732 DHX38 -0.5 -8.28 -0.41 2.85e-15 Fibrinogen levels; LIHC cis rs11148252 0.553 rs2147692 chr13:53287023 C/G cg00495681 chr13:53174319 NA 0.72 13.06 0.58 6.5e-32 Lewy body disease; LIHC trans rs6073597 1.000 rs6031980 chr20:43714384 C/T cg00459129 chr12:27167463 TM7SF3 0.46 6.56 0.33 2.05e-10 Positive affect; LIHC cis rs4759375 1.000 rs10846506 chr12:123777815 G/T cg00376283 chr12:123451042 ABCB9 -0.49 -6.31 -0.32 8.53e-10 HDL cholesterol; LIHC cis rs736408 0.677 rs2286798 chr3:52821177 G/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.47 -7.62 -0.38 2.48e-13 Bipolar disorder; LIHC cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg05025164 chr4:1340916 KIAA1530 0.79 12.86 0.57 3.74e-31 Longevity; LIHC cis rs999943 0.774 rs12205634 chr6:33611667 C/G cg14003231 chr6:33640908 ITPR3 0.4 7.02 0.35 1.19e-11 Obesity (extreme); LIHC cis rs3106136 0.843 rs6826671 chr4:95271881 T/C cg11021082 chr4:95130006 SMARCAD1 0.43 7.5 0.38 5.5e-13 Capecitabine sensitivity; LIHC cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs68170813 0.559 rs74387778 chr7:106963213 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.85 -0.3 1.17e-8 Coronary artery disease; LIHC cis rs908922 0.742 rs499913 chr1:152476743 T/A cg20991723 chr1:152506922 NA 0.39 5.92 0.3 8.04e-9 Hair morphology; LIHC cis rs11997175 0.624 rs12677772 chr8:33772521 T/C ch.8.33884649F chr8:33765107 NA 0.33 5.93 0.31 7.53e-9 Body mass index; LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.15 0.55 1.79e-28 Prudent dietary pattern; LIHC cis rs12701220 0.894 rs12701406 chr7:1050283 G/A cg00990874 chr7:1149470 C7orf50 -0.7 -9.74 -0.47 6.04e-20 Bronchopulmonary dysplasia; LIHC cis rs11608355 0.545 rs4766474 chr12:109908084 G/C cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs11792861 0.962 rs3750454 chr9:111801325 C/G cg05043794 chr9:111880884 C9orf5 0.3 7.01 0.35 1.27e-11 Menarche (age at onset); LIHC cis rs7552404 1.000 rs6672180 chr1:76123973 C/G cg22875332 chr1:76189707 ACADM 0.49 7.26 0.37 2.69e-12 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09299307 chr5:86709023 CCNH 0.48 7.52 0.38 5e-13 Cognitive function; LIHC cis rs8044868 0.530 rs12918956 chr16:72224335 A/G cg16558253 chr16:72132732 DHX38 0.36 5.91 0.3 8.22e-9 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs1003719 0.715 rs8126941 chr21:38551542 T/A cg10648535 chr21:38446584 PIGP;TTC3 -0.64 -9.52 -0.46 3.37e-19 Eye color traits; LIHC cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg27297192 chr10:134578999 INPP5A 0.5 7.03 0.36 1.11e-11 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs600806 0.778 rs4970761 chr1:109995398 C/T cg11161837 chr1:110010384 SYPL2 0.44 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis); LIHC cis rs2991971 0.934 rs11211129 chr1:45983080 C/T cg15605315 chr1:45957053 TESK2 0.48 6.42 0.33 4.45e-10 High light scatter reticulocyte count; LIHC cis rs10791097 0.694 rs4936123 chr11:130740967 G/A cg22079354 chr11:130786696 SNX19 0.39 5.74 0.3 2.14e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.28e-9 Menopause (age at onset); LIHC cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg25204440 chr1:209979598 IRF6 0.51 7.82 0.39 6.45e-14 Cleft lip with or without cleft palate; LIHC cis rs7512552 0.839 rs7523428 chr1:150430472 G/A cg15654264 chr1:150340011 RPRD2 0.68 11.19 0.52 5.8e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9309711 0.643 rs4535074 chr2:3481637 A/G cg15506890 chr2:3487001 NA -0.46 -7.46 -0.37 7.32e-13 Neurofibrillary tangles; LIHC cis rs35306767 0.904 rs35667562 chr10:950630 G/A cg20503657 chr10:835505 NA 1.35 14.48 0.62 2.1e-37 Eosinophil percentage of granulocytes; LIHC cis rs7674212 0.570 rs2711899 chr4:104062414 T/C cg16532752 chr4:104119610 CENPE -0.43 -6.58 -0.34 1.79e-10 Type 2 diabetes; LIHC cis rs1728785 1.000 rs1170428 chr16:68603988 C/A cg02972257 chr16:68554789 NA -0.57 -6.51 -0.33 2.7e-10 Ulcerative colitis; LIHC cis rs911119 0.866 rs4815223 chr20:23577112 C/A cg16589663 chr20:23618590 CST3 0.67 7.01 0.35 1.29e-11 Chronic kidney disease; LIHC cis rs2839186 0.632 rs17176110 chr21:47706535 C/A cg00612595 chr21:47717864 NA -0.38 -6.22 -0.32 1.48e-9 Testicular germ cell tumor; LIHC cis rs858239 0.539 rs4294098 chr7:23185995 G/A cg23682824 chr7:23144976 KLHL7 0.43 6.45 0.33 3.76e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs1003719 0.613 rs9978998 chr21:38535848 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs244731 0.959 rs10037110 chr5:176658066 A/T cg17509989 chr5:176798049 RGS14 -0.68 -6.38 -0.33 5.82e-10 Urate levels in lean individuals; LIHC cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg27170947 chr2:26402098 FAM59B -0.7 -8.57 -0.42 3.57e-16 Gut microbiome composition (summer); LIHC cis rs13108904 0.846 rs12643212 chr4:1224948 A/G cg13395646 chr4:1353034 KIAA1530 -0.55 -7.75 -0.39 1.03e-13 Obesity-related traits; LIHC cis rs7647973 0.769 rs6446204 chr3:49034879 T/C cg07636037 chr3:49044803 WDR6 0.75 8.93 0.43 2.65e-17 Menarche (age at onset); LIHC cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg08645402 chr16:4508243 NA 0.4 7.09 0.36 7.89e-12 Schizophrenia; LIHC cis rs3008870 0.920 rs12132532 chr1:67457015 G/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg00149659 chr3:10157352 C3orf10 0.6 6.57 0.33 1.82e-10 Alzheimer's disease; LIHC cis rs1336900 0.637 rs35967040 chr1:150555588 A/C cg13175981 chr1:150552382 MCL1 0.54 7.32 0.37 1.74e-12 Blood protein levels; LIHC cis rs763121 0.819 rs5757161 chr22:38990662 G/A cg14440974 chr22:39074834 NA -0.36 -6.06 -0.31 3.56e-9 Menopause (age at onset); LIHC cis rs2842992 0.830 rs2025189 chr6:160137518 C/T cg11366901 chr6:160182831 ACAT2 0.95 16.21 0.66 2.97e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs240764 0.614 rs12210312 chr6:101170849 A/G cg09795085 chr6:101329169 ASCC3 -0.43 -6.03 -0.31 4.17e-9 Neuroticism; LIHC cis rs929354 0.772 rs1182432 chr7:157029176 A/G cg17757837 chr7:157058334 UBE3C 0.72 11.92 0.54 1.2e-27 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11147586 chr5:170845829 FGF18 0.42 6.04 0.31 4.04e-9 Lung function (FEV1/FVC); LIHC cis rs7909074 1.000 rs10900128 chr10:45393201 G/T cg05187965 chr10:45406764 TMEM72 -0.28 -6.95 -0.35 1.9e-11 Mean corpuscular volume; LIHC cis rs68170813 0.559 rs76299183 chr7:106904859 A/G cg02696742 chr7:106810147 HBP1 -0.53 -6.22 -0.32 1.44e-9 Coronary artery disease; LIHC cis rs6547741 1.000 rs6737921 chr2:27839107 T/C cg27432699 chr2:27873401 GPN1 0.71 11.6 0.53 1.87e-26 Oral cavity cancer; LIHC cis rs6952808 0.782 rs4236271 chr7:1881369 C/T cg04267008 chr7:1944627 MAD1L1 -0.58 -9.21 -0.45 3.4e-18 Bipolar disorder and schizophrenia; LIHC cis rs6754311 0.593 rs55825471 chr2:136526981 T/A cg17750252 chr2:136567154 LCT 0.35 6.15 0.32 2.12e-9 Mosquito bite size; LIHC cis rs950169 0.922 rs11633534 chr15:85124642 C/T cg17507749 chr15:85114479 UBE2QP1 0.75 8.51 0.42 5.72e-16 Schizophrenia; LIHC cis rs992157 1.000 rs4791 chr2:219138940 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.84 0.57 4.36e-31 Colorectal cancer; LIHC cis rs8114671 0.552 rs2024635 chr20:33422614 G/A cg07148914 chr20:33460835 GGT7 0.61 9.01 0.44 1.49e-17 Height; LIHC cis rs1355223 0.872 rs12785367 chr11:34715269 G/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.42 -0.33 4.62e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs910316 1.000 rs3742778 chr14:75538217 A/C cg08847533 chr14:75593920 NEK9 -0.92 -20.81 -0.75 1.05e-62 Height; LIHC cis rs3741404 0.609 rs666497 chr11:63869821 G/C cg18225595 chr11:63971243 STIP1 0.45 7.27 0.37 2.4e-12 Platelet count; LIHC cis rs7258465 0.897 rs1043327 chr19:18554972 A/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.35 -0.37 1.44e-12 Breast cancer; LIHC cis rs6060960 0.537 rs75351461 chr20:30458612 C/T cg13852791 chr20:30311386 BCL2L1 0.75 6.77 0.34 5.55e-11 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; LIHC cis rs2404602 0.647 rs116090606 chr15:77075209 A/G cg03037974 chr15:76606532 NA -0.61 -10.37 -0.49 4.39e-22 Blood metabolite levels; LIHC cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg21782813 chr7:2030301 MAD1L1 0.51 9.1 0.44 7.81e-18 Bipolar disorder and schizophrenia; LIHC cis rs1552244 0.882 rs13077641 chr3:10022935 G/A cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs60871478 0.730 rs62432226 chr7:792973 T/C cg04727924 chr7:799746 HEATR2 -0.59 -7.89 -0.39 4.22e-14 Cerebrospinal P-tau181p levels; LIHC cis rs6430585 0.528 rs309123 chr2:136761175 C/G cg07169764 chr2:136633963 MCM6 0.99 15.06 0.63 1.08e-39 Corneal structure; LIHC cis rs2841277 0.646 rs2819419 chr14:105406238 A/C cg15352829 chr14:105391018 PLD4 -0.44 -9.3 -0.45 1.76e-18 Rheumatoid arthritis; LIHC cis rs1707322 0.682 rs28508523 chr1:46189625 G/A cg06784218 chr1:46089804 CCDC17 0.4 7.49 0.38 6.04e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7666738 0.546 rs13148080 chr4:98680947 A/G cg05340658 chr4:99064831 C4orf37 0.49 6.26 0.32 1.16e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7903847 0.620 rs10882903 chr10:99115584 A/T cg06359132 chr10:99160096 RRP12 -0.39 -6.03 -0.31 4.3e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs9733 0.596 rs12072339 chr1:150686099 A/G cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC cis rs9318086 0.648 rs35449605 chr13:24472582 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.55 10.7 0.5 3.1e-23 Myopia (pathological); LIHC cis rs1419980 0.730 rs11054896 chr12:7774131 A/G cg10578777 chr12:7781093 NA -0.39 -5.79 -0.3 1.55e-8 HDL cholesterol levels; LIHC cis rs4820294 1.000 rs739139 chr22:38067011 C/G cg00142150 chr22:38071001 LGALS1 0.7 11.47 0.53 5.34e-26 Fat distribution (HIV); LIHC cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.46 6.36 0.33 6.34e-10 Schizophrenia; LIHC cis rs1401999 0.836 rs34571027 chr3:183726644 T/C cg01324343 chr3:183735012 ABCC5 0.73 11.86 0.54 2.13e-27 Anterior chamber depth; LIHC cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs11252926 0.565 rs4881308 chr10:484983 G/T cg09445902 chr10:555545 DIP2C -0.38 -6.21 -0.32 1.52e-9 Psychosis in Alzheimer's disease; LIHC cis rs6582630 0.519 rs9738104 chr12:38338459 A/C cg26384229 chr12:38710491 ALG10B 0.86 10.72 0.5 2.7e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs7618501 1.000 rs7374183 chr3:49785133 G/A cg21467203 chr3:49911342 NA 0.39 6.64 0.34 1.2e-10 Intelligence (multi-trait analysis); LIHC cis rs1707322 1.000 rs4660903 chr1:46457601 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.54 0.33 2.2e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1577917 0.958 rs10944144 chr6:86537755 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.48 -7.63 -0.38 2.39e-13 Response to antipsychotic treatment; LIHC cis rs67311347 0.866 rs3214006 chr3:40352134 C/T cg13409248 chr3:40428643 ENTPD3 0.38 5.9 0.3 8.59e-9 Renal cell carcinoma; LIHC cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg24004478 chr7:855632 UNC84A 0.37 5.95 0.31 6.74e-9 Perceived unattractiveness to mosquitoes; LIHC trans rs72960926 0.744 rs7755776 chr6:74967405 C/G cg07247405 chr1:2484626 LOC115110 -0.55 -6.57 -0.33 1.86e-10 Metabolite levels (MHPG); LIHC cis rs7937682 0.883 rs568038 chr11:111432161 A/C cg09085632 chr11:111637200 PPP2R1B 0.9 11.03 0.51 2.07e-24 Primary sclerosing cholangitis; LIHC cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.02 0.55 5.22e-28 Prudent dietary pattern; LIHC cis rs7927592 0.956 rs7944870 chr11:68309108 C/G cg01657329 chr11:68192670 LRP5 -0.45 -5.91 -0.3 8.25e-9 Total body bone mineral density; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg16132339 chr22:24313637 DDTL;DDT 0.7 13.3 0.58 7.96e-33 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7224685 0.506 rs12452569 chr17:4023667 T/A cg11204139 chr17:3907470 NA 0.59 6.93 0.35 2.13e-11 Type 2 diabetes; LIHC cis rs6088590 0.965 rs6087619 chr20:33288511 C/G cg24642439 chr20:33292090 TP53INP2 0.83 11.95 0.54 9.98e-28 Coronary artery disease; LIHC cis rs7246657 0.943 rs7252099 chr19:37933780 G/A cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs644799 1.000 rs472231 chr11:95532166 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.86 0.47 2.45e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg10217327 chr6:118973057 C6orf204 0.69 7.04 0.36 1.03e-11 Diastolic blood pressure; LIHC cis rs2274273 0.870 rs3783650 chr14:55848972 A/C cg01864836 chr14:55583639 NA -0.41 -7.61 -0.38 2.63e-13 Protein biomarker; LIHC cis rs8023580 1.000 rs8023580 chr15:96708291 T/C cg01739960 chr15:96715164 NA 0.36 5.79 0.3 1.62e-8 Sex hormone-binding globulin levels; LIHC cis rs4820294 1.000 rs78974622 chr22:38059925 A/C cg00292662 chr22:38071168 LGALS1 0.63 10.04 0.48 6.04e-21 Fat distribution (HIV); LIHC cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.48 0.56 1.07e-29 Alzheimer's disease; LIHC cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg10560079 chr2:191398806 TMEM194B -0.49 -7.55 -0.38 4.01e-13 Pulse pressure; LIHC cis rs68170813 0.559 rs77185844 chr7:106812916 A/C cg02696742 chr7:106810147 HBP1 -0.5 -5.8 -0.3 1.52e-8 Coronary artery disease; LIHC cis rs362296 0.698 rs3095082 chr4:3263617 C/A cg06533319 chr4:3265114 C4orf44 0.35 6.66 0.34 1.09e-10 Parental longevity (mother's age at death); LIHC cis rs12711979 0.740 rs6711964 chr2:3820916 A/T cg17052675 chr2:3827356 NA -0.42 -7.19 -0.36 4.16e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs12765878 1.000 rs61277100 chr10:105643352 A/G cg11005552 chr10:105648138 OBFC1 0.39 6.16 0.32 2.08e-9 Coronary artery disease; LIHC cis rs7772486 0.790 rs9376971 chr6:146259505 C/T cg05347473 chr6:146136440 FBXO30 -0.36 -5.86 -0.3 1.07e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.58e-21 Intelligence (multi-trait analysis); LIHC cis rs7666738 0.519 rs28539191 chr4:98821552 C/T cg05340658 chr4:99064831 C4orf37 0.49 6.46 0.33 3.65e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg16434002 chr17:42200994 HDAC5 0.48 7.03 0.36 1.14e-11 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25154432 chr5:79703725 ZFYVE16 0.44 6.06 0.31 3.57e-9 Pancreatic cancer; LIHC cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg12311346 chr5:56204834 C5orf35 -0.57 -7.58 -0.38 3.37e-13 Initial pursuit acceleration; LIHC cis rs2845885 0.793 rs57779243 chr11:63882363 G/T cg05555928 chr11:63887634 MACROD1 -0.51 -7.07 -0.36 8.6e-12 Body mass index; LIHC cis rs1865760 0.786 rs1436308 chr6:25939567 T/G cg17691542 chr6:26056736 HIST1H1C 0.4 5.95 0.31 6.6e-9 Height; LIHC cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg18252515 chr7:66147081 NA -1.3 -16.62 -0.67 6.84e-46 Diabetic kidney disease; LIHC cis rs539514 0.664 rs560069 chr13:76309344 A/G cg04757411 chr13:76259545 LMO7 0.42 7.24 0.36 3.06e-12 Type 1 diabetes; LIHC trans rs1912702 0.592 rs17138382 chr11:79174380 G/T cg18020480 chr1:174186816 RABGAP1L -0.45 -6.24 -0.32 1.27e-9 Hair greying; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg24947615 chr21:44515479 U2AF1 0.41 6.08 0.31 3.28e-9 Immature fraction of reticulocytes; LIHC cis rs2016586 0.895 rs5995156 chr22:36105236 A/C cg26342177 chr22:36113512 APOL5 -0.37 -6.31 -0.32 8.52e-10 Body mass index; LIHC cis rs7246657 0.943 rs7246993 chr19:37890154 C/T cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs2073499 1.000 rs2073498 chr3:50369546 C/A cg09545109 chr3:50388910 TUSC4;CYB561D2 0.79 8.17 0.4 6.22e-15 Schizophrenia; LIHC cis rs5769765 1.000 rs2319458 chr22:50236306 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.69 -8.75 -0.43 9.75e-17 Schizophrenia; LIHC cis rs11864453 1.000 rs11864453 chr16:72050480 C/T cg01557791 chr16:72042693 DHODH -0.71 -11.16 -0.52 6.98e-25 Fibrinogen levels; LIHC cis rs9420 0.961 rs11605731 chr11:57524089 C/G cg19752551 chr11:57585705 CTNND1 -0.51 -7.17 -0.36 4.8e-12 Schizophrenia; LIHC cis rs10193935 1.000 rs58962161 chr2:42400278 T/A cg27598129 chr2:42591480 NA -0.75 -11.57 -0.53 2.3e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2932538 0.961 rs6690292 chr1:113188419 C/T cg22162597 chr1:113214053 CAPZA1 -0.69 -10.84 -0.51 9.52e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs35110281 1.000 rs35110281 chr21:45068947 T/A cg21573476 chr21:45109991 RRP1B -0.57 -10.79 -0.5 1.54e-23 Mean corpuscular volume; LIHC cis rs16912285 0.585 rs7950920 chr11:24356464 G/A ch.11.24196551F chr11:24239977 NA 0.67 7.65 0.38 2.13e-13 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs3020736 0.500 rs6002603 chr22:42492362 C/G cg00645731 chr22:42541494 CYP2D7P1 -0.4 -6.23 -0.32 1.39e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs904251 0.523 rs9369005 chr6:37483109 A/G cg08126542 chr6:37504118 NA -0.36 -6.25 -0.32 1.19e-9 Cognitive performance; LIHC cis rs11098499 0.863 rs6858777 chr4:120475966 A/G cg09307838 chr4:120376055 NA 0.75 11.33 0.52 1.79e-25 Corneal astigmatism; LIHC cis rs9911578 0.967 rs8182277 chr17:57144367 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -8.99 -0.44 1.67e-17 Intelligence (multi-trait analysis); LIHC cis rs7192750 0.562 rs9888748 chr16:71987851 G/A cg06353428 chr16:71660113 MARVELD3 0.77 8.89 0.43 3.46e-17 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs6918586 0.658 rs198854 chr6:26104057 T/C cg18357526 chr6:26021779 HIST1H4A -0.56 -8.3 -0.41 2.45e-15 Schizophrenia; LIHC cis rs903552 1.000 rs12903048 chr15:102006325 G/T cg25677261 chr15:102009856 PCSK6 -0.44 -5.95 -0.31 6.77e-9 Diabetic kidney disease; LIHC cis rs11864453 0.560 rs6499561 chr16:72148404 A/G cg16558253 chr16:72132732 DHX38 -0.5 -8.03 -0.4 1.58e-14 Fibrinogen levels; LIHC cis rs6061231 0.571 rs482010 chr20:60927551 A/G cg06026331 chr20:60912101 LAMA5 -0.51 -8.61 -0.42 2.67e-16 Colorectal cancer; LIHC cis rs801193 1.000 rs2659909 chr7:66160279 G/A cg18876405 chr7:65276391 NA 0.41 6.98 0.35 1.55e-11 Aortic root size; LIHC cis rs950169 0.922 rs4842940 chr15:84831225 C/T cg17507749 chr15:85114479 UBE2QP1 -0.73 -8.81 -0.43 6.38e-17 Schizophrenia; LIHC cis rs9733 0.818 rs10888388 chr1:150687296 C/T cg17724175 chr1:150552817 MCL1 -0.38 -7.85 -0.39 5.49e-14 Tonsillectomy; LIHC cis rs2479106 0.553 rs3739827 chr9:126690157 A/G cg16191174 chr9:126692580 DENND1A -0.52 -5.87 -0.3 1.04e-8 Polycystic ovary syndrome; LIHC cis rs1707322 0.721 rs4564187 chr1:46166861 G/C cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs921968 0.612 rs496908 chr2:219357742 A/T cg02985541 chr2:219472218 PLCD4 0.45 8.41 0.41 1.09e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs903552 1.000 rs8043379 chr15:102005837 A/G cg19295451 chr15:102010161 PCSK6 -0.46 -6.33 -0.32 7.51e-10 Diabetic kidney disease; LIHC cis rs12368653 0.616 rs1027315 chr12:58034192 T/C cg12615879 chr12:58013172 SLC26A10 0.35 6.84 0.35 3.73e-11 Multiple sclerosis; LIHC cis rs6840360 0.593 rs1429559 chr4:152681952 A/G cg22705602 chr4:152727874 NA -0.4 -8.39 -0.41 1.29e-15 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs67895180 chr3:10026079 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs67311347 1.000 rs28434528 chr3:40484893 A/G cg13409248 chr3:40428643 ENTPD3 0.41 6.9 0.35 2.58e-11 Renal cell carcinoma; LIHC trans rs7504990 0.802 rs11533771 chr18:50393300 G/A cg08535148 chr4:26321143 RBPJ 0.52 6.14 0.32 2.33e-9 Gallbladder cancer; LIHC cis rs11718455 0.538 rs1524887 chr3:44016371 C/T cg08738300 chr3:44038990 NA 0.34 6.09 0.31 3.09e-9 Coronary artery disease; LIHC cis rs1555399 0.792 rs2273596 chr14:67981870 T/C cg16224230 chr14:67978224 TMEM229B -0.24 -5.84 -0.3 1.25e-8 Parkinson's disease; LIHC cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.79 15.05 0.63 1.22e-39 Menarche (age at onset); LIHC cis rs4917833 0.738 rs35898407 chr10:100221150 A/G cg19043522 chr10:100227446 HPSE2 0.41 5.78 0.3 1.68e-8 Pediatric bone mineral density (femoral neck); LIHC cis rs6748734 0.779 rs6437371 chr2:241797424 G/C cg08694578 chr2:241835147 C2orf54 -0.51 -8.01 -0.4 1.8e-14 Urinary metabolites; LIHC cis rs4423214 1.000 rs3794060 chr11:71187679 C/T cg05163923 chr11:71159392 DHCR7 0.88 13.26 0.58 1.1e-32 Vitamin D levels; LIHC cis rs9534288 0.797 rs2404727 chr13:46581697 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg17547399 chr2:54197573 PSME4 -0.44 -6.4 -0.33 5.04e-10 Calcium levels; LIHC cis rs1712517 0.771 rs11191645 chr10:105059308 G/T cg05636881 chr10:105038444 INA 0.5 7.86 0.39 5.11e-14 Migraine; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03532005 chr7:56119028 CCT6A;PSPH -0.48 -6.19 -0.32 1.73e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg00057700 chr10:124768526 ACADSB;IKZF5 -0.53 -6.04 -0.31 4.07e-9 Systolic blood pressure; LIHC cis rs986417 1.000 rs8015462 chr14:61046687 G/A cg27398547 chr14:60952738 C14orf39 0.82 9.31 0.45 1.55e-18 Gut microbiota (bacterial taxa); LIHC cis rs2282802 0.685 rs11745502 chr5:139558808 G/A cg26211634 chr5:139558579 C5orf32 -0.39 -6.05 -0.31 3.82e-9 Intelligence (multi-trait analysis); LIHC cis rs4423214 0.840 rs1790328 chr11:71148038 G/A cg05163923 chr11:71159392 DHCR7 -0.62 -8.52 -0.42 5e-16 Vitamin D levels; LIHC trans rs1814175 0.817 rs10839351 chr11:49758153 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.32e-11 Height; LIHC cis rs6429082 0.871 rs6675944 chr1:235572669 C/T cg26050004 chr1:235667680 B3GALNT2 0.41 6.65 0.34 1.15e-10 Adiposity; LIHC cis rs9858542 0.953 rs35261698 chr3:49537839 C/G cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs780096 0.506 rs1728922 chr2:27644464 A/C cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.85 -0.3 1.16e-8 Total body bone mineral density; LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg21448741 chr8:58168803 NA 0.35 6.55 0.33 2.1e-10 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.908 rs56351880 chr22:50316597 A/G cg02269571 chr22:50332266 NA -0.65 -8.8 -0.43 6.68e-17 Schizophrenia; LIHC cis rs1577917 0.958 rs12191340 chr6:86521400 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.11 -0.4 9.1e-15 Response to antipsychotic treatment; LIHC cis rs7542091 0.669 rs7540534 chr1:210044824 A/T cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg05584439 chr11:47213196 NA 0.42 6.05 0.31 3.73e-9 Longevity; LIHC cis rs8078723 0.966 rs7021 chr17:38153875 T/A cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.22 -0.45 3.13e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg21724239 chr8:58056113 NA 0.58 6.68 0.34 9.98e-11 Developmental language disorder (linguistic errors); LIHC trans rs80033912 0.640 rs6785832 chr3:49224316 C/T cg21659725 chr3:3221576 CRBN 0.47 6.28 0.32 1.03e-9 Intelligence (multi-trait analysis); LIHC cis rs7395581 0.959 rs2013867 chr11:47260272 A/G cg26139080 chr11:47293733 MADD -0.49 -8.29 -0.41 2.6e-15 HDL cholesterol; LIHC cis rs10751667 0.666 rs10902241 chr11:949129 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.16 0.48 2.3e-21 Alzheimer's disease (late onset); LIHC cis rs2842992 0.789 rs9364536 chr6:160225559 G/C cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.89 0.43 3.49e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs1707322 1.000 rs11211222 chr1:46367757 T/C cg03146154 chr1:46216737 IPP 0.48 7.75 0.39 1.03e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.93 9.41 0.45 7.75e-19 Platelet count; LIHC cis rs244293 0.899 rs244309 chr17:53212093 C/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs9942416 0.585 rs253409 chr5:74928069 C/G cg19683494 chr5:74908142 NA -0.5 -6.6 -0.34 1.56e-10 Age-related disease endophenotypes; LIHC cis rs754466 0.651 rs11815015 chr10:79625482 C/T cg17075019 chr10:79541650 NA -0.75 -11.49 -0.53 4.54e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs644799 1.000 rs12291986 chr11:95523030 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.69 9.86 0.47 2.31e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9818758 0.607 rs113186424 chr3:49272726 T/C cg00383909 chr3:49044727 WDR6 0.8 6.81 0.35 4.29e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs208520 0.789 rs9351549 chr6:66871851 A/G cg07460842 chr6:66804631 NA -0.79 -8.82 -0.43 5.87e-17 Exhaled nitric oxide output; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg09047471 chr8:56792345 LYN 0.46 6.54 0.33 2.24e-10 Migraine with aura; LIHC cis rs7020830 0.898 rs7857936 chr9:37078491 T/C cg14294708 chr9:37120828 ZCCHC7 1.0 20.55 0.74 1.11e-61 Schizophrenia; LIHC cis rs2070488 0.965 rs3762791 chr3:38568828 T/C cg24069376 chr3:38537580 EXOG -0.38 -6.86 -0.35 3.26e-11 Electrocardiographic conduction measures; LIHC cis rs9828933 0.766 rs864975 chr3:63885615 T/C cg16258503 chr3:63850278 ATXN7;THOC7 0.81 10.11 0.48 3.37e-21 Type 2 diabetes; LIHC cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg19774624 chr17:42201019 HDAC5 -0.79 -12.28 -0.55 5.92e-29 Total body bone mineral density; LIHC trans rs208520 1.000 rs72882100 chr6:66981495 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.09 0.36 7.85e-12 Exhaled nitric oxide output; LIHC cis rs7107174 0.748 rs2063730 chr11:78048524 A/C cg02023728 chr11:77925099 USP35 0.44 8.41 0.41 1.09e-15 Testicular germ cell tumor; LIHC cis rs1448094 0.512 rs10863086 chr12:86244225 G/A cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs12915845 0.545 rs12911061 chr15:89066635 T/A cg05013243 chr15:89149849 MIR1179 -0.38 -6.88 -0.35 2.87e-11 Menarche (age at onset); LIHC cis rs1882538 0.538 rs9649587 chr7:133104569 A/C cg10665199 chr7:133106180 EXOC4 0.52 8.75 0.43 1.02e-16 Intelligence (multi-trait analysis); LIHC cis rs8062405 1.000 rs62036626 chr16:28844284 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.28 0.32 1.06e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs12500482 0.935 rs12644638 chr4:2413461 C/T cg08330972 chr4:2403930 ZFYVE28 -0.35 -5.87 -0.3 1.03e-8 Cognitive function; LIHC cis rs11690935 0.959 rs10803863 chr2:172535337 T/C cg13550731 chr2:172543902 DYNC1I2 0.92 17.64 0.69 5.57e-50 Schizophrenia; LIHC cis rs929354 0.713 rs1034785 chr7:157002383 T/C cg05182265 chr7:156933206 UBE3C -0.32 -5.99 -0.31 5.22e-9 Body mass index; LIHC cis rs59901009 0.954 rs56319831 chr11:10179849 A/G cg01453529 chr11:10209919 SBF2 -0.31 -6.05 -0.31 3.87e-9 Hematocrit;Hemoglobin concentration; LIHC cis rs12464559 0.649 rs4664499 chr2:152584153 A/C cg01189475 chr2:152685088 ARL5A 0.61 7.42 0.37 9.07e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs9614461 0.702 rs16993867 chr22:45733199 A/G cg18180155 chr22:45809454 SMC1B;RIBC2 0.48 5.83 0.3 1.27e-8 Tonsillectomy; LIHC cis rs2404602 0.583 rs12913096 chr15:76551852 C/T cg23625390 chr15:77176239 SCAPER 0.35 6.17 0.32 1.96e-9 Blood metabolite levels; LIHC cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg05564831 chr3:52568323 NT5DC2 0.36 5.88 0.3 9.67e-9 Bipolar disorder; LIHC cis rs8062405 0.755 rs7193402 chr16:28586127 A/G cg07382826 chr16:28625726 SULT1A1 0.48 7.58 0.38 3.25e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg13409248 chr3:40428643 ENTPD3 -0.5 -8.37 -0.41 1.54e-15 Renal cell carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08722104 chr11:47448306 PSMC3 0.47 6.72 0.34 7.67e-11 Pancreatic cancer; LIHC cis rs11229555 0.609 rs12286421 chr11:58174898 A/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7572733 0.515 rs6726506 chr2:198846486 G/T cg10820045 chr2:198174542 NA 0.46 6.99 0.35 1.42e-11 Dermatomyositis; LIHC cis rs903552 1.000 rs12906575 chr15:102003617 G/A cg06707286 chr15:102010195 PCSK6 -0.43 -6.09 -0.31 3.08e-9 Diabetic kidney disease; LIHC cis rs12220238 1.000 rs1908331 chr10:75885817 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.65 6.53 0.33 2.33e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs79387448 0.592 rs76362690 chr2:102951477 A/G cg09003973 chr2:102972529 NA 1.13 8.67 0.42 1.71e-16 Gut microbiota (bacterial taxa); LIHC cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg15320075 chr8:145703422 NA -0.55 -9.46 -0.46 5.3e-19 Age at first birth; LIHC cis rs6952808 0.929 rs12699483 chr7:1975624 C/G cg20295408 chr7:1910781 MAD1L1 -0.45 -6.51 -0.33 2.6200000000000003e-10 Bipolar disorder and schizophrenia; LIHC cis rs757110 0.770 rs4439492 chr11:17386733 C/T cg15432903 chr11:17409602 KCNJ11 0.65 10.12 0.48 3.11e-21 Type 2 diabetes; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg23126947 chr3:93780364 NSUN3;DHFRL1 0.34 6.1 0.31 2.83e-9 Hepatitis; LIHC cis rs986417 1.000 rs1951114 chr14:60922005 C/G cg27398547 chr14:60952738 C14orf39 -0.81 -9.56 -0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs798766 1.000 rs3099555 chr4:1725651 T/C cg21231739 chr4:1642635 FAM53A -0.36 -5.87 -0.3 1.04e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs7208859 0.725 rs9891656 chr17:29243355 A/T cg13385521 chr17:29058706 SUZ12P 0.71 7.39 0.37 1.17e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg19927065 chr19:1122678 SBNO2 0.45 6.17 0.32 1.97e-9 Hip circumference; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07161146 chr7:151526959 PRKAG2 0.41 6.38 0.33 5.7e-10 Longevity; LIHC cis rs6502050 0.835 rs10163483 chr17:80110396 C/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs28489187 0.683 rs1498373 chr1:85790633 G/A cg16011679 chr1:85725395 C1orf52 0.48 6.15 0.32 2.13e-9 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs11971779 0.680 rs66491565 chr7:139088977 C/G cg07862535 chr7:139043722 LUC7L2 0.64 11.08 0.51 1.44e-24 Diisocyanate-induced asthma; LIHC cis rs4466137 0.868 rs4703962 chr5:82999808 A/G cg16102102 chr5:83017553 HAPLN1 -0.58 -8.43 -0.41 9.97e-16 Prostate cancer; LIHC cis rs7587476 0.862 rs13001462 chr2:215678346 G/A cg04004882 chr2:215674386 BARD1 0.57 7.86 0.39 5.11e-14 Neuroblastoma; LIHC cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg26818010 chr10:134567672 INPP5A 0.76 9.24 0.45 2.75e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs12701220 0.744 rs10499317 chr7:1012103 C/G cg00990874 chr7:1149470 C7orf50 -0.4 -6.11 -0.31 2.73e-9 Bronchopulmonary dysplasia; LIHC cis rs6754311 0.731 rs1470457 chr2:136581848 A/G cg15123519 chr2:136567270 LCT -0.39 -7.81 -0.39 6.95e-14 Mosquito bite size; LIHC cis rs6964587 0.626 rs404 chr7:91544316 G/T cg17063962 chr7:91808500 NA -0.61 -11.03 -0.51 2.06e-24 Breast cancer; LIHC cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg18252515 chr7:66147081 NA 1.26 17.23 0.68 2.57e-48 Diabetic kidney disease; LIHC cis rs7927771 0.832 rs10838704 chr11:47424717 T/C cg20307385 chr11:47447363 PSMC3 -0.48 -6.18 -0.32 1.8e-9 Subjective well-being; LIHC cis rs79387448 0.655 rs75579337 chr2:102917302 C/A cg09003973 chr2:102972529 NA 1.2 9.65 0.46 1.2e-19 Gut microbiota (bacterial taxa); LIHC cis rs4742903 1.000 rs10761010 chr9:106858788 G/A cg14250997 chr9:106856677 SMC2 0.43 7.67 0.38 1.76e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs7772486 0.875 rs9399572 chr6:146362945 T/G cg13319975 chr6:146136371 FBXO30 -0.34 -5.74 -0.3 2.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs798554 0.796 rs2533884 chr7:2836848 T/G cg13628971 chr7:2884303 GNA12 0.52 7.36 0.37 1.4e-12 Height; LIHC cis rs1873147 0.569 rs58819603 chr15:63310866 T/A cg12160578 chr15:63334699 TPM1 0.67 8.87 0.43 4.13e-17 Orofacial clefts; LIHC cis rs4819052 0.679 rs2255761 chr21:46683622 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 10.11 0.48 3.35e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7617773 0.779 rs77957078 chr3:48331286 G/C cg11946769 chr3:48343235 NME6 0.9 11.48 0.53 5.19e-26 Coronary artery disease; LIHC cis rs1042058 0.565 rs650110 chr10:30753132 A/G cg25182066 chr10:30743637 MAP3K8 -0.69 -10.97 -0.51 3.51e-24 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.79 0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs4906332 1.000 rs12885234 chr14:103889181 A/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.26 -0.32 1.12e-9 Coronary artery disease; LIHC cis rs17401966 0.931 rs1555849 chr1:10400602 G/T cg15208524 chr1:10270712 KIF1B -0.4 -5.93 -0.31 7.23e-9 Hepatocellular carcinoma; LIHC cis rs11148252 0.875 rs9568728 chr13:52946593 C/T cg00495681 chr13:53174319 NA 0.39 6.38 0.33 5.65e-10 Lewy body disease; LIHC cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg03354898 chr7:1950403 MAD1L1 -0.36 -5.83 -0.3 1.26e-8 Bipolar disorder and schizophrenia; LIHC cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.862 rs3926380 chr7:66080645 G/T cg18876405 chr7:65276391 NA -0.34 -6.24 -0.32 1.3e-9 Aortic root size; LIHC cis rs875971 0.545 rs2173571 chr7:65770379 G/A cg11764359 chr7:65958608 NA 0.58 8.16 0.4 6.57e-15 Aortic root size; LIHC cis rs2976388 0.609 rs1594999 chr8:143790574 G/A cg06565975 chr8:143823917 SLURP1 0.33 6.41 0.33 4.92e-10 Urinary tract infection frequency; LIHC cis rs9486715 0.867 rs9373829 chr6:96897201 A/C cg06623918 chr6:96969491 KIAA0776 -0.84 -14.06 -0.61 9.75e-36 Headache; LIHC cis rs7772486 0.846 rs2144478 chr6:146381445 A/G cg13319975 chr6:146136371 FBXO30 -0.34 -5.76 -0.3 1.89e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs6570726 0.577 rs9497315 chr6:145791967 C/T cg23711669 chr6:146136114 FBXO30 -0.58 -7.98 -0.4 2.21e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg10295955 chr4:187884368 NA -0.96 -22.55 -0.77 1.2e-69 Lobe attachment (rater-scored or self-reported); LIHC cis rs769267 0.965 rs2965188 chr19:19522557 G/A cg03709012 chr19:19516395 GATAD2A 1.02 18.24 0.7 2.09e-52 Tonsillectomy; LIHC cis rs9303401 0.659 rs35103007 chr17:56900738 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.95 13.32 0.58 7.02e-33 Cognitive test performance; LIHC cis rs2304069 0.954 rs6861548 chr5:149384680 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.99 13.02 0.58 9.43e-32 HIV-1 control; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18240814 chr5:107718300 FBXL17 -0.5 -6.65 -0.34 1.18e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs61550741 1.000 rs73191630 chr21:32499726 C/T cg23515853 chr17:79372528 BAHCC1 -0.65 -6.19 -0.32 1.71e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs875971 1.000 rs778694 chr7:65871558 A/G cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs13191362 0.872 rs13213421 chr6:163203805 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.8 6.71 0.34 8.29e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg18230493 chr5:56204884 C5orf35 -0.47 -6.6 -0.34 1.58e-10 Initial pursuit acceleration; LIHC cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg18654377 chr3:49208889 KLHDC8B -0.5 -5.9 -0.3 8.98e-9 Menarche (age at onset); LIHC cis rs67311347 1.000 rs6795475 chr3:40489281 A/G cg13409248 chr3:40428643 ENTPD3 0.41 6.91 0.35 2.42e-11 Renal cell carcinoma; LIHC cis rs600806 0.683 rs10857788 chr1:110012289 G/A cg11161837 chr1:110010384 SYPL2 0.48 6.53 0.33 2.35e-10 Intelligence (multi-trait analysis); LIHC trans rs10213084 1.000 rs7670221 chr4:147497597 G/C cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs780096 0.546 rs2293572 chr2:27728777 C/G cg27432699 chr2:27873401 GPN1 0.59 8.6 0.42 2.84e-16 Total body bone mineral density; LIHC cis rs12906542 0.507 rs4395040 chr15:78282533 G/A cg22832135 chr15:78370102 TBC1D2B 0.65 8.34 0.41 1.91e-15 Breast cancer; LIHC cis rs7927771 0.524 rs4539273 chr11:47694699 C/T cg20307385 chr11:47447363 PSMC3 -0.71 -10.72 -0.5 2.52e-23 Subjective well-being; LIHC cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg08499158 chr17:42289980 UBTF -0.49 -7.9 -0.39 3.82e-14 Total body bone mineral density; LIHC cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg26939375 chr7:64535504 NA 0.47 7.19 0.36 4.13e-12 Aortic root size; LIHC cis rs11112613 0.609 rs17037380 chr12:106036708 C/T cg03607813 chr12:105948248 NA 0.44 6.9 0.35 2.51e-11 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.26 0.55 6.62e-29 Prudent dietary pattern; LIHC cis rs6089584 0.526 rs6089316 chr20:60627552 C/T cg23262073 chr20:60523788 NA -0.28 -5.78 -0.3 1.65e-8 Body mass index; LIHC cis rs317689 0.876 rs547332 chr12:69743639 C/G cg20891283 chr12:69753455 YEATS4 0.7 11.06 0.51 1.63e-24 Response to diuretic therapy; LIHC cis rs3204270 0.673 rs62077190 chr17:79676109 C/A cg18367735 chr17:79674897 NA 0.73 8.24 0.41 3.72e-15 Dental caries; LIHC cis rs4975616 0.714 rs27069 chr5:1347128 C/T cg06550200 chr5:1325588 CLPTM1L -0.6 -9.25 -0.45 2.44e-18 Lung cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08715805 chr2:45870883 NA 0.53 7.0 0.35 1.33e-11 Lung function (FEV1/FVC); LIHC cis rs4803468 0.967 rs11670583 chr19:41920440 A/T cg14132834 chr19:41945861 ATP5SL -0.43 -6.4 -0.33 5.17e-10 Height; LIHC cis rs763121 0.853 rs138706 chr22:39137834 C/G cg06544989 chr22:39130855 UNC84B 0.4 6.59 0.34 1.62e-10 Menopause (age at onset); LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08431062 chr19:16607243 C19orf44;CALR3 0.39 6.33 0.32 7.55e-10 Cognitive function; LIHC cis rs9549367 0.826 rs1885688 chr13:113894236 G/T cg00898013 chr13:113819073 PROZ -0.36 -6.45 -0.33 3.85e-10 Platelet distribution width; LIHC trans rs75804782 0.641 rs72987327 chr2:239359833 T/G cg01134436 chr17:81009848 B3GNTL1 0.8 6.79 0.34 4.97e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs7607369 0.572 rs629177 chr2:219454801 T/G cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.43e-13 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.14 11.55 0.53 2.76e-26 Platelet count; LIHC cis rs2303745 0.589 rs1864116 chr19:17393015 C/T cg04248312 chr19:17393744 ANKLE1 -0.74 -12.37 -0.56 2.77e-29 Systemic lupus erythematosus; LIHC cis rs651907 0.535 rs12631513 chr3:101517476 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs77106637 0.585 rs12292949 chr11:72457531 C/T cg03713592 chr11:72463424 ARAP1 0.62 6.8 0.35 4.55e-11 Type 2 diabetes; LIHC cis rs10078 0.515 rs6872510 chr5:481610 T/C cg08916839 chr5:415575 AHRR 0.59 11.96 0.54 8.81e-28 Fat distribution (HIV); LIHC cis rs5769765 0.908 rs138889 chr22:50226673 T/C cg02269571 chr22:50332266 NA -0.62 -8.43 -0.41 9.8e-16 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04697482 chr19:16989084 SIN3B 0.42 6.23 0.32 1.38e-9 Longevity; LIHC cis rs11122272 0.735 rs2486727 chr1:231539245 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.28 0.45 2.05e-18 Hemoglobin concentration; LIHC cis rs11122272 0.764 rs4486439 chr1:231477470 C/T cg06096015 chr1:231504339 EGLN1 0.5 9.39 0.45 9e-19 Hemoglobin concentration; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.55 8.53 0.42 4.92e-16 Height; LIHC cis rs9309473 1.000 rs1534471 chr2:73647508 G/A cg20560298 chr2:73613845 ALMS1 -0.53 -6.75 -0.34 6.53e-11 Metabolite levels; LIHC cis rs8180040 0.966 rs11705957 chr3:47443262 T/G cg27129171 chr3:47204927 SETD2 -0.56 -9.42 -0.45 6.69e-19 Colorectal cancer; LIHC cis rs7249142 0.562 rs2239370 chr19:19292674 T/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.37 -6.11 -0.31 2.65e-9 IgG glycosylation; LIHC cis rs6546550 0.935 rs7563062 chr2:70050725 G/A cg02498382 chr2:70120550 SNRNP27 -0.4 -6.58 -0.34 1.72e-10 Prevalent atrial fibrillation; LIHC cis rs875971 1.000 rs12698523 chr7:65968113 C/G cg18876405 chr7:65276391 NA 0.37 6.75 0.34 6.44e-11 Aortic root size; LIHC cis rs801193 0.569 rs7800620 chr7:66223688 T/C cg18252515 chr7:66147081 NA -0.47 -6.86 -0.35 3.2e-11 Aortic root size; LIHC cis rs2404602 0.552 rs11636612 chr15:76959530 C/T cg03037974 chr15:76606532 NA -0.5 -7.77 -0.39 9.47e-14 Blood metabolite levels; LIHC trans rs61931739 0.534 rs10844728 chr12:34020109 G/C cg26384229 chr12:38710491 ALG10B 0.52 7.2 0.36 3.74e-12 Morning vs. evening chronotype; LIHC cis rs11229555 0.874 rs10896787 chr11:58285494 G/T cg15696309 chr11:58395628 NA -0.7 -8.34 -0.41 1.8e-15 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs918629 0.530 rs1423269 chr5:95255724 A/G cg10483112 chr5:95245456 ELL2 -0.38 -6.99 -0.35 1.47e-11 IgG glycosylation; LIHC cis rs2070488 0.662 rs7375040 chr3:38469116 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.58 8.12 0.4 8.44e-15 Electrocardiographic conduction measures; LIHC cis rs13191362 0.935 rs73023493 chr6:162952769 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.73 6.12 0.31 2.52e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs11105298 0.891 rs11105287 chr12:89829470 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.56 -6.43 -0.33 4.27e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.78 -0.54 3.97e-27 Alzheimer's disease; LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg11070056 chr1:107600091 PRMT6 -0.66 -10.87 -0.51 7.54e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2404602 0.583 rs2176623 chr15:76568579 C/T cg22467129 chr15:76604101 ETFA -0.38 -6.32 -0.32 8.08e-10 Blood metabolite levels; LIHC cis rs4975709 0.801 rs3797063 chr5:1881549 A/T cg15595755 chr5:1867978 NA 0.34 6.38 0.33 5.83e-10 Cardiovascular disease risk factors; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04351903 chr1:202162209 LGR6 0.46 6.27 0.32 1.1e-9 Lung function (FEV1/FVC); LIHC cis rs7095944 0.614 rs7898003 chr10:126451385 G/A cg08799069 chr10:126477246 METTL10 -0.38 -6.75 -0.34 6.32e-11 Asthma; LIHC cis rs6815814 0.851 rs11466617 chr4:38780471 T/C cg06935464 chr4:38784597 TLR10 0.48 7.39 0.37 1.11e-12 Breast cancer; LIHC cis rs7131987 0.903 rs2194520 chr12:29423712 C/T cg12903224 chr12:29470962 FAR2 -0.38 -5.99 -0.31 5.36e-9 QT interval; LIHC cis rs9911578 1.000 rs9907499 chr17:56949044 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs7044106 0.791 rs2416799 chr9:123480866 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.11 0.52 1.07e-24 Hip circumference adjusted for BMI; LIHC trans rs1464321 0.851 rs10778229 chr12:103692799 G/T cg15403093 chr12:133312361 ANKLE2 0.41 6.41 0.33 4.7e-10 Body mass index; LIHC cis rs921968 0.541 rs588770 chr2:219494638 T/C cg02176678 chr2:219576539 TTLL4 0.54 7.53 0.38 4.49e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs703842 0.892 rs1021469 chr12:58208164 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.78 12.53 0.56 6.7e-30 Multiple sclerosis; LIHC cis rs10751667 0.666 rs7394958 chr11:965944 C/G cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs9611519 1.000 rs9611510 chr22:41569124 T/C cg03806693 chr22:41940476 POLR3H -0.73 -8.2 -0.41 4.98e-15 Neuroticism; LIHC cis rs1538970 0.924 rs11211118 chr1:45930270 A/C cg24296786 chr1:45957014 TESK2 -0.51 -7.45 -0.37 7.79e-13 Platelet count; LIHC cis rs365132 1.000 rs365132 chr5:176378574 G/T cg16309518 chr5:176445507 NA -0.58 -11.44 -0.53 7.23e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs3096299 0.869 rs748941 chr16:89440754 T/A cg08822215 chr16:89438651 ANKRD11 -0.49 -7.9 -0.39 3.92e-14 Multiple myeloma (IgH translocation); LIHC cis rs1865760 0.516 rs9379818 chr6:26023206 G/T cg17691542 chr6:26056736 HIST1H1C 0.43 6.2 0.32 1.6e-9 Height; LIHC cis rs2066819 1.000 rs744051 chr12:56667298 C/T cg26714650 chr12:56694279 CS 1.4 13.79 0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs2806561 0.808 rs12128178 chr1:23354814 C/T cg19743168 chr1:23544995 NA -0.36 -6.64 -0.34 1.26e-10 Height; LIHC cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg15556689 chr8:8085844 FLJ10661 -0.4 -6.56 -0.33 1.98e-10 Mood instability; LIHC cis rs1059312 0.808 rs4760537 chr12:129301299 C/A cg09035930 chr12:129282057 SLC15A4 0.6 11.17 0.52 6.7e-25 Systemic lupus erythematosus; LIHC cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg18252515 chr7:66147081 NA -1.27 -16.32 -0.66 1.13e-44 Diabetic kidney disease; LIHC cis rs9911578 1.000 rs304296 chr17:56834229 G/T cg12560992 chr17:57184187 TRIM37 0.97 17.46 0.69 2.94e-49 Intelligence (multi-trait analysis); LIHC trans rs9914544 0.524 rs7209853 chr17:18798600 G/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.53 -0.33 2.44e-10 Educational attainment (years of education); LIHC cis rs1371867 0.846 rs2439460 chr8:101312665 C/T cg06636551 chr8:101224915 SPAG1 -0.47 -8.76 -0.43 9.03e-17 Atrioventricular conduction; LIHC trans rs7734985 0.728 rs6556904 chr5:95495637 G/C cg07951579 chr16:10863179 NUBP1;FAM18A 0.34 6.05 0.31 3.89e-9 IgG glycosylation; LIHC cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.69 0.34 9.33e-11 Bipolar disorder; LIHC cis rs317689 0.613 rs315112 chr12:69785926 T/A cg14784868 chr12:69753453 YEATS4 0.83 15.52 0.64 1.74e-41 Response to diuretic therapy; LIHC cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg23172400 chr8:95962367 TP53INP1 -0.37 -8.01 -0.4 1.79e-14 Type 2 diabetes; LIHC trans rs61931739 0.517 rs11052964 chr12:34010996 G/C cg26384229 chr12:38710491 ALG10B 0.52 7.23 0.36 3.11e-12 Morning vs. evening chronotype; LIHC cis rs8072100 0.967 rs8072644 chr17:45653364 A/T cg08085267 chr17:45401833 C17orf57 0.39 5.84 0.3 1.24e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2576037 0.526 rs658756 chr18:44431832 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.14 -0.36 5.73e-12 Personality dimensions; LIHC cis rs2153535 0.580 rs9393019 chr6:8462091 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.21e-26 Motion sickness; LIHC cis rs919433 0.929 rs1366836 chr2:198172148 T/G cg03934865 chr2:198174659 NA -0.6 -9.65 -0.46 1.16e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2832191 0.755 rs2832193 chr21:30493589 T/C cg08807101 chr21:30365312 RNF160 -0.56 -8.82 -0.43 5.84e-17 Dental caries; LIHC cis rs3106136 0.967 rs2306802 chr4:95186055 A/G cg11021082 chr4:95130006 SMARCAD1 -0.34 -6.36 -0.33 6.32e-10 Capecitabine sensitivity; LIHC cis rs11229555 0.609 rs12289198 chr11:58175057 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs66573146 0.572 rs55740475 chr4:6954092 C/G cg07817883 chr1:32538562 TMEM39B 1.02 9.01 0.44 1.54e-17 Granulocyte percentage of myeloid white cells; LIHC cis rs6879260 0.714 rs888926 chr5:179738101 A/G cg23248424 chr5:179741104 GFPT2 -0.46 -6.93 -0.35 2.11e-11 Height; LIHC cis rs941873 0.868 rs12780295 chr10:81115438 G/A cg11057378 chr10:81107060 PPIF 0.37 6.01 0.31 4.75e-9 Height; LIHC cis rs17376456 0.825 rs13165400 chr5:93091427 G/A cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC cis rs826838 1.000 rs11168218 chr12:38884466 A/G cg26384229 chr12:38710491 ALG10B 0.98 13.3 0.58 7.84e-33 Heart rate; LIHC cis rs67311347 0.577 rs11712626 chr3:40259927 G/A cg18306943 chr3:40428807 ENTPD3 0.38 6.33 0.32 7.63e-10 Renal cell carcinoma; LIHC cis rs7089973 0.604 rs12218498 chr10:116578489 T/C cg03647239 chr10:116582469 FAM160B1 0.42 5.94 0.31 6.94e-9 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4843747 0.636 rs11117358 chr16:88105053 T/A cg06050784 chr16:88016603 BANP 0.35 6.46 0.33 3.5e-10 Menopause (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18125479 chr14:51411049 PYGL 0.39 6.11 0.31 2.67e-9 Cognitive function; LIHC cis rs7772486 0.875 rs2748482 chr6:146336532 T/C cg13319975 chr6:146136371 FBXO30 -0.37 -6.05 -0.31 3.71e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1005277 0.579 rs1740732 chr10:38491385 C/T cg27523141 chr10:43048294 ZNF37B 0.38 6.49 0.33 2.94e-10 Extrinsic epigenetic age acceleration; LIHC cis rs881375 0.678 rs10818488 chr9:123705087 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.42 6.16 0.32 2.04e-9 Rheumatoid arthritis; LIHC cis rs7107174 0.901 rs10899497 chr11:78124534 T/C cg02023728 chr11:77925099 USP35 0.41 7.34 0.37 1.6e-12 Testicular germ cell tumor; LIHC cis rs9818758 0.607 rs13077498 chr3:49313978 C/T cg06212747 chr3:49208901 KLHDC8B -0.68 -5.82 -0.3 1.36e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs4728302 0.869 rs10255193 chr7:133608911 C/G cg10665199 chr7:133106180 EXOC4 0.39 6.81 0.35 4.48e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7940866 0.804 rs3910267 chr11:130810282 C/T cg12179176 chr11:130786555 SNX19 0.64 9.3 0.45 1.72e-18 Schizophrenia; LIHC cis rs427394 0.802 rs274698 chr5:6730957 T/G cg10857441 chr5:6722123 POLS -0.36 -6.3 -0.32 8.93e-10 Menopause (age at onset); LIHC cis rs875971 0.964 rs55748098 chr7:65763618 T/C cg18876405 chr7:65276391 NA -0.37 -6.73 -0.34 7.14e-11 Aortic root size; LIHC cis rs7264396 0.623 rs761827 chr20:34207897 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -8.82 -0.43 5.91e-17 Total cholesterol levels; LIHC trans rs2073499 0.935 rs2624840 chr3:50199015 T/C cg21659725 chr3:3221576 CRBN -0.63 -6.69 -0.34 8.98e-11 Schizophrenia; LIHC cis rs17270561 0.609 rs7746502 chr6:25718762 T/A cg17691542 chr6:26056736 HIST1H1C -0.48 -6.3 -0.32 8.97e-10 Iron status biomarkers; LIHC cis rs6430585 0.528 rs6750549 chr2:136707480 A/G cg07169764 chr2:136633963 MCM6 1.28 21.87 0.76 6.17e-67 Corneal structure; LIHC cis rs208520 0.526 rs9354366 chr6:66788559 C/T cg07460842 chr6:66804631 NA -1.03 -20.04 -0.73 1.2e-59 Exhaled nitric oxide output; LIHC cis rs2257205 0.667 rs9912325 chr17:56873934 A/G cg12560992 chr17:57184187 TRIM37 0.68 7.44 0.37 8.24e-13 Pancreatic cancer; LIHC cis rs6502050 0.835 rs4789670 chr17:80151805 T/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.91 -0.3 8.14e-9 Life satisfaction; LIHC cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg02187348 chr16:89574699 SPG7 0.63 9.97 0.47 1.01e-20 Multiple myeloma (IgH translocation); LIHC trans rs1814175 0.791 rs10769625 chr11:49869887 G/A cg03929089 chr4:120376271 NA -0.89 -18.29 -0.7 1.34e-52 Height; LIHC cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg06238570 chr21:40685208 BRWD1 -0.52 -8.57 -0.42 3.55e-16 Cognitive function; LIHC cis rs11190604 1.000 rs11190595 chr10:102291761 T/C cg07080220 chr10:102295463 HIF1AN 0.57 8.09 0.4 1.05e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs34172651 0.517 rs874484 chr16:24803242 T/C cg04756594 chr16:24857601 SLC5A11 0.61 8.79 0.43 7.54e-17 Intelligence (multi-trait analysis); LIHC cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg03452623 chr4:187889614 NA -0.32 -8.44 -0.42 9.36e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs1691799 0.899 rs1168293 chr12:66733904 G/A cg16791601 chr12:66731901 HELB -0.54 -12.97 -0.57 1.47e-31 White blood cell count (basophil); LIHC cis rs7945705 0.875 rs2568065 chr11:8889648 C/T cg12365402 chr11:9010492 NRIP3 -0.26 -6.61 -0.34 1.43e-10 Hemoglobin concentration; LIHC cis rs763014 0.966 rs4984904 chr16:680809 C/G cg00802000 chr16:706648 WDR90 -0.39 -6.31 -0.32 8.43e-10 Height; LIHC cis rs5769765 0.740 rs2103932 chr22:50272515 A/G cg02269571 chr22:50332266 NA 0.6 8.52 0.42 5.24e-16 Schizophrenia; LIHC cis rs9457247 0.646 rs4710160 chr6:167409241 T/A cg23791538 chr6:167370224 RNASET2 -0.64 -10.82 -0.51 1.13e-23 Crohn's disease; LIHC cis rs11971779 0.648 rs7799165 chr7:139084957 G/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs12950390 0.853 rs12450733 chr17:45855404 A/G cg03474202 chr17:45855739 NA -0.34 -5.9 -0.3 8.75e-9 IgG glycosylation; LIHC cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg18225595 chr11:63971243 STIP1 0.64 8.1 0.4 1e-14 Mean platelet volume; LIHC cis rs7119038 0.818 rs6589684 chr11:118610957 A/G cg19308663 chr11:118741387 NA -0.43 -5.92 -0.3 7.78e-9 Sjögren's syndrome; LIHC cis rs8017423 0.904 rs11848894 chr14:90723660 C/A cg14092571 chr14:90743983 NA -0.38 -6.03 -0.31 4.15e-9 Mortality in heart failure; LIHC cis rs11764590 0.694 rs4721321 chr7:2068470 A/G cg23422044 chr7:1970798 MAD1L1 -0.52 -7.97 -0.4 2.47e-14 Neuroticism; LIHC trans rs2832077 0.883 rs35672956 chr21:30189042 T/C cg14791747 chr16:20752902 THUMPD1 0.47 6.29 0.32 9.64e-10 Cognitive test performance; LIHC cis rs2274273 0.870 rs1952087 chr14:55683211 A/C cg04306507 chr14:55594613 LGALS3 0.33 6.19 0.32 1.7e-9 Protein biomarker; LIHC cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg22800045 chr5:56110881 MAP3K1 0.67 8.51 0.42 5.54e-16 Initial pursuit acceleration; LIHC cis rs6547741 1.000 rs10205364 chr2:27794233 C/T cg27432699 chr2:27873401 GPN1 0.72 11.74 0.54 5.55e-27 Oral cavity cancer; LIHC cis rs1801251 0.896 rs921054 chr2:233694673 G/A cg08000102 chr2:233561755 GIGYF2 -0.75 -10.96 -0.51 3.82e-24 Coronary artery disease; LIHC trans rs10213084 1.000 rs10212917 chr4:147499315 T/C cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg02290350 chr8:58132656 NA 0.49 10.56 0.5 9.22e-23 Developmental language disorder (linguistic errors); LIHC cis rs9818758 0.607 rs13087930 chr3:48961726 A/G cg00383909 chr3:49044727 WDR6 0.96 7.95 0.4 2.65e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1000083 0.915 rs10463199 chr5:96545475 C/T ch.5.96698337R chr5:96672581 NA -0.8 -6.75 -0.34 6.31e-11 Cisplatin-induced ototoxicity; LIHC cis rs2439831 0.867 rs16957627 chr15:43642657 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC cis rs4665809 1.000 rs750450 chr2:26324631 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.73 -9.11 -0.44 6.99e-18 Gut microbiome composition (summer); LIHC cis rs67478160 0.643 rs3742369 chr14:104251276 T/C cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.11 -0.36 6.77e-12 Schizophrenia; LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg09074113 chr2:20870087 GDF7 -0.51 -10.31 -0.49 6.76e-22 Abdominal aortic aneurysm; LIHC cis rs12368653 0.641 rs11172300 chr12:58076515 C/T cg12615879 chr12:58013172 SLC26A10 0.37 6.89 0.35 2.69e-11 Multiple sclerosis; LIHC cis rs7131987 0.903 rs6487796 chr12:29422764 A/G cg14222432 chr12:29376421 FAR2 0.37 7.13 0.36 5.83e-12 QT interval; LIHC cis rs9611519 0.894 rs9623320 chr22:41478482 G/A cg06634786 chr22:41940651 POLR3H -0.52 -5.75 -0.3 2.01e-8 Neuroticism; LIHC cis rs765787 0.530 rs28414644 chr15:45536721 G/C cg25801113 chr15:45476975 SHF 0.37 6.31 0.32 8.86e-10 Uric acid levels; LIHC cis rs11628318 0.515 rs4906239 chr14:103078073 A/G cg12046867 chr14:103022105 NA -0.38 -5.73 -0.3 2.16e-8 Platelet count; LIHC cis rs1577917 0.958 rs13201730 chr6:86556647 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.18 -0.52 6.29e-25 Response to antipsychotic treatment; LIHC cis rs17685 0.523 rs10246583 chr7:75746667 C/A cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.89e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17539620 0.628 rs62432729 chr6:154830044 T/C cg17771515 chr6:154831774 CNKSR3 0.59 6.27 0.32 1.1e-9 Lipoprotein (a) levels; LIHC cis rs7312774 0.618 rs4964503 chr12:107335937 C/G cg16260113 chr12:107380972 MTERFD3 -0.87 -11.02 -0.51 2.3e-24 Severe influenza A (H1N1) infection; LIHC cis rs8180040 0.966 rs7628631 chr3:47560863 C/T cg27129171 chr3:47204927 SETD2 -0.5 -8.04 -0.4 1.53e-14 Colorectal cancer; LIHC cis rs6120849 0.708 rs6087659 chr20:33606383 C/A cg24642439 chr20:33292090 TP53INP2 0.66 7.22 0.36 3.41e-12 Protein C levels; LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg18306943 chr3:40428807 ENTPD3 -0.42 -7.46 -0.37 7.18e-13 Renal cell carcinoma; LIHC cis rs2832191 0.647 rs11170 chr21:30378090 C/T cg24692254 chr21:30365293 RNF160 0.82 14.35 0.61 6.81e-37 Dental caries; LIHC cis rs6840360 0.615 rs12647462 chr4:152607278 C/T cg22705602 chr4:152727874 NA -0.32 -6.75 -0.34 6.3e-11 Intelligence (multi-trait analysis); LIHC cis rs7618501 1.000 rs7372730 chr3:49790682 C/G cg24110177 chr3:50126178 RBM5 0.42 6.47 0.33 3.43e-10 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs11636367 chr15:45535862 A/G cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs4332037 0.522 rs4721098 chr7:1881527 G/C cg23422044 chr7:1970798 MAD1L1 0.54 6.61 0.34 1.43e-10 Bipolar disorder; LIHC trans rs17685 0.884 rs8565 chr7:75630274 T/C cg19862616 chr7:65841803 NCRNA00174 -0.73 -12.92 -0.57 2.25e-31 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs950776 0.518 rs12906951 chr15:78825562 C/T cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs7937682 0.883 rs1789358 chr11:111474116 G/A cg09085632 chr11:111637200 PPP2R1B -0.93 -11.29 -0.52 2.55e-25 Primary sclerosing cholangitis; LIHC cis rs35306767 1.000 rs35306767 chr10:989437 A/T cg20503657 chr10:835505 NA 1.0 9.76 0.47 5.08e-20 Eosinophil percentage of granulocytes; LIHC cis rs7246657 0.943 rs9304566 chr19:37845504 T/C cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC trans rs11039798 0.512 rs1588069 chr11:48694871 A/G cg03929089 chr4:120376271 NA 0.53 6.13 0.31 2.36e-9 Axial length; LIHC cis rs10857712 0.703 rs12253520 chr10:135235321 C/A cg19623624 chr10:135278901 LOC619207 -0.45 -6.97 -0.35 1.65e-11 Systemic lupus erythematosus; LIHC cis rs6088590 1.000 rs6088595 chr20:33358499 T/A cg24642439 chr20:33292090 TP53INP2 0.83 11.23 0.52 4.18e-25 Coronary artery disease; LIHC cis rs7677751 0.767 rs6831380 chr4:55076345 G/A cg17187183 chr4:55093834 PDGFRA 0.58 7.49 0.38 5.82e-13 Corneal astigmatism; LIHC cis rs4906332 1.000 rs35344594 chr14:103955792 A/G cg04998671 chr14:104000505 TRMT61A -0.46 -6.26 -0.32 1.17e-9 Coronary artery disease; LIHC cis rs826838 0.900 rs11169301 chr12:39128497 C/A cg13010199 chr12:38710504 ALG10B 0.51 6.19 0.32 1.69e-9 Heart rate; LIHC cis rs860295 0.812 rs12407800 chr1:155760742 A/C cg02153340 chr1:155202674 NA -0.33 -6.11 -0.31 2.73e-9 Body mass index; LIHC cis rs4144743 1.000 rs34182248 chr17:45321359 T/C cg18085866 chr17:45331354 ITGB3 -0.55 -7.81 -0.39 6.9e-14 Body mass index; LIHC cis rs4728302 0.869 rs11770927 chr7:133593126 G/A cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.34 0.81 1.72e-80 Prudent dietary pattern; LIHC cis rs155076 1.000 rs598754 chr13:21845010 C/A cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.3e-30 White matter hyperintensity burden; LIHC trans rs7714584 1.000 rs7714415 chr5:150270292 A/G cg20675040 chr8:143813288 C8orf55 0.34 6.12 0.31 2.54e-9 Crohn's disease; LIHC cis rs1003719 0.762 rs2835590 chr21:38463406 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs2073300 1.000 rs6137957 chr20:23437384 G/A cg16736954 chr20:23401023 NAPB 0.54 6.02 0.31 4.6e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10751667 0.961 rs7943115 chr11:973885 T/C cg06064525 chr11:970664 AP2A2 -0.49 -12.33 -0.55 3.84e-29 Alzheimer's disease (late onset); LIHC cis rs1843834 1.000 rs4624372 chr2:225553128 A/G cg22455342 chr2:225449267 CUL3 0.45 6.17 0.32 1.95e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs7208859 0.623 rs9893422 chr17:29111715 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg07677032 chr17:61819896 STRADA 0.41 6.05 0.31 3.91e-9 Prudent dietary pattern; LIHC cis rs6714710 0.580 rs57804205 chr2:98454472 G/A cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.56 8.2 0.41 4.92e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6087990 0.568 rs853854 chr20:31420757 T/A cg13636640 chr20:31349939 DNMT3B 0.72 12.93 0.57 2.01e-31 Ulcerative colitis; LIHC trans rs7618501 0.573 rs2624824 chr3:50088266 T/C cg21659725 chr3:3221576 CRBN -0.67 -10.75 -0.5 2.02e-23 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.522 rs289643 chr10:37941494 T/G cg27523141 chr10:43048294 ZNF37B 0.35 6.09 0.31 3.06e-9 Extrinsic epigenetic age acceleration; LIHC cis rs62229266 0.647 rs59397717 chr21:37451725 C/T cg12218747 chr21:37451666 NA -0.43 -7.03 -0.36 1.15e-11 Mitral valve prolapse; LIHC cis rs2016586 0.895 rs4821438 chr22:36114047 C/T cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 7.96e-10 Body mass index; LIHC cis rs7917772 0.502 rs2296583 chr10:104244322 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.49 0.56 9.88e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg00280220 chr17:61926910 NA 0.42 6.87 0.35 3.08e-11 Prudent dietary pattern; LIHC trans rs6952808 0.825 rs11761818 chr7:1935273 C/T cg04565464 chr8:145669602 NFKBIL2 0.39 6.09 0.31 3.01e-9 Bipolar disorder and schizophrenia; LIHC cis rs17685 0.753 rs10085567 chr7:75734206 A/C cg04592579 chr7:75616294 TMEM120A 0.37 6.41 0.33 4.8e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs875971 0.825 rs4587224 chr7:65736182 G/A cg18876405 chr7:65276391 NA -0.35 -6.37 -0.33 6.12e-10 Aortic root size; LIHC cis rs2228479 0.702 rs11646374 chr16:89857935 G/A cg04013166 chr16:89971882 TCF25 0.49 5.91 0.3 8.48e-9 Skin colour saturation; LIHC cis rs8180040 0.654 rs4682831 chr3:47027138 A/G cg02527881 chr3:46936655 PTH1R 0.33 6.33 0.32 7.78e-10 Colorectal cancer; LIHC cis rs2760061 0.626 rs592736 chr1:228116831 A/G cg02753203 chr1:228287806 NA -0.45 -7.18 -0.36 4.27e-12 Diastolic blood pressure; LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg04013166 chr16:89971882 TCF25 0.63 8.86 0.43 4.53e-17 Skin colour saturation; LIHC cis rs55665837 0.559 rs11023210 chr11:14422762 A/G cg19336497 chr11:14380999 RRAS2 0.58 10.77 0.5 1.8e-23 Vitamin D levels; LIHC cis rs9783347 1.000 rs4150661 chr11:18379629 C/A cg15585147 chr11:18324498 HPS5 0.37 6.08 0.31 3.21e-9 Pancreatic cancer; LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.13 0.4 7.83e-15 Height; LIHC cis rs8192917 1.000 rs6573910 chr14:25100882 A/G cg03875678 chr14:25103546 GZMB -0.42 -7.6 -0.38 2.95e-13 Vitiligo; LIHC cis rs1577917 1.000 rs34106666 chr6:86676258 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -10.06 -0.48 5.08e-21 Response to antipsychotic treatment; LIHC cis rs9303401 0.614 rs7215900 chr17:56654850 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.93 12.18 0.55 1.34e-28 Cognitive test performance; LIHC cis rs6545883 0.894 rs1186703 chr2:61672965 A/C cg15711740 chr2:61764176 XPO1 -0.44 -6.09 -0.31 3.02e-9 Tuberculosis; LIHC cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg15691649 chr6:25882328 NA -0.45 -5.89 -0.3 9.05e-9 Intelligence (multi-trait analysis); LIHC cis rs58688157 0.705 rs12419694 chr11:598033 C/T cg16486109 chr11:613632 IRF7 0.58 6.32 0.32 8.09e-10 Systemic lupus erythematosus; LIHC cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.1 11.21 0.52 4.58e-25 Platelet count; LIHC cis rs2273156 1.000 rs7141292 chr14:35462906 T/A cg16230307 chr14:35515116 FAM177A1 -0.41 -6.01 -0.31 4.78e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs7116495 0.609 rs1894004 chr11:71759817 G/A cg10381502 chr11:71823885 C11orf51 -1.08 -9.2 -0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs9888615 1.000 rs9888615 chr14:53377540 T/C cg00686598 chr14:53173677 PSMC6 -0.5 -6.2 -0.32 1.59e-9 Systolic blood pressure; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05790002 chr16:82033681 SDR42E1 0.49 6.75 0.34 6.2e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7224685 0.569 rs7213885 chr17:4018489 T/A cg09597638 chr17:3907349 NA 0.54 6.49 0.33 2.98e-10 Type 2 diabetes; LIHC cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg20684491 chr1:25596433 NA 0.29 5.83 0.3 1.25e-8 Erythrocyte sedimentation rate; LIHC cis rs2412488 0.927 rs931181 chr4:54243074 T/C cg22241045 chr4:54363911 LNX1 -0.4 -6.48 -0.33 3.15e-10 DNA methylation (variation); LIHC cis rs7208859 0.623 rs7217984 chr17:29092766 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.93 0.35 2.06e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9322817 0.603 rs9386426 chr6:105165367 A/G cg02098413 chr6:105308735 HACE1 -0.36 -5.77 -0.3 1.73e-8 Thyroid stimulating hormone; LIHC cis rs7772486 0.902 rs1331643 chr6:146398873 T/A cg23711669 chr6:146136114 FBXO30 0.53 9.48 0.46 4.55e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs9296092 0.517 rs9461876 chr6:33516657 C/T cg13560919 chr6:33536144 NA -0.39 -6.33 -0.32 7.6e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.6 0.34 1.6e-10 Bipolar disorder; LIHC cis rs9300255 0.602 rs1106241 chr12:123627016 T/C cg00376283 chr12:123451042 ABCB9 0.57 6.52 0.33 2.6e-10 Neutrophil percentage of white cells; LIHC cis rs9640161 0.659 rs11975886 chr7:150010362 G/A cg21361702 chr7:150065534 REPIN1 0.48 6.63 0.34 1.29e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs2836950 0.545 rs11701805 chr21:40618683 T/C cg17971929 chr21:40555470 PSMG1 -0.41 -6.02 -0.31 4.38e-9 Menarche (age at onset); LIHC cis rs4332037 0.539 rs55790766 chr7:2021248 C/T cg23422044 chr7:1970798 MAD1L1 -0.62 -6.93 -0.35 2.11e-11 Bipolar disorder; LIHC cis rs4319547 0.794 rs61954972 chr12:123074167 T/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.95 -0.39 2.84e-14 Body mass index; LIHC cis rs12477438 0.822 rs6727170 chr2:99588042 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.03 -12.46 -0.56 1.21e-29 Chronic sinus infection; LIHC cis rs2842992 0.724 rs1128670 chr6:160211636 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg13393036 chr8:95962371 TP53INP1 -0.45 -10.89 -0.51 6.78e-24 Type 2 diabetes; LIHC cis rs2067615 0.579 rs4964492 chr12:107222774 C/T cg15890332 chr12:107067104 RFX4 0.26 5.94 0.31 7.09e-9 Heart rate; LIHC cis rs9858542 0.953 rs34363169 chr3:49537712 G/A cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9486715 1.000 rs6902835 chr6:97063005 C/G cg06623918 chr6:96969491 KIAA0776 -0.84 -14.17 -0.61 3.66e-36 Headache; LIHC cis rs3780378 0.935 rs7875908 chr9:5081334 C/T cg02405213 chr9:5042618 JAK2 -0.51 -8.74 -0.43 1.1e-16 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC trans rs6952808 0.692 rs11773316 chr7:2027354 C/T cg04565464 chr8:145669602 NFKBIL2 0.4 6.64 0.34 1.23e-10 Bipolar disorder and schizophrenia; LIHC cis rs4766897 0.543 rs10850001 chr12:112553032 T/A cg01169073 chr12:112280321 C12orf47;MAPKAPK5 0.39 5.92 0.31 7.63e-9 Fibrinogen levels; LIHC cis rs11971779 0.648 rs6967836 chr7:139079944 C/G cg07862535 chr7:139043722 LUC7L2 0.6 10.44 0.49 2.56e-22 Diisocyanate-induced asthma; LIHC cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg24693881 chr1:107596107 NA 0.56 9.78 0.47 4.41e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.519 rs10788792 chr1:150638572 T/G cg18016565 chr1:150552671 MCL1 0.6 11.78 0.54 4.02e-27 Tonsillectomy; LIHC cis rs523522 0.962 rs670568 chr12:121021206 C/T cg12219531 chr12:120966889 COQ5 0.68 13.23 0.58 1.46e-32 High light scatter reticulocyte count; LIHC cis rs77637988 0.578 rs7577237 chr2:48601816 A/G cg00032884 chr2:48540671 FOXN2 -0.41 -6.48 -0.33 3.14e-10 Joint mobility (Beighton score); LIHC cis rs6952808 0.929 rs11761270 chr7:1923695 C/T cg02951883 chr7:2050386 MAD1L1 -0.61 -9.39 -0.45 9.01e-19 Bipolar disorder and schizophrenia; LIHC cis rs7818688 0.697 rs112411609 chr8:95980854 C/A cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs7618501 0.633 rs9814664 chr3:50078541 C/T cg21659725 chr3:3221576 CRBN -0.67 -10.89 -0.51 6.46e-24 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg10755058 chr3:40428713 ENTPD3 0.41 7.17 0.36 4.59e-12 Renal cell carcinoma; LIHC cis rs9309473 0.519 rs1083922 chr2:73704003 A/G cg20560298 chr2:73613845 ALMS1 0.36 5.91 0.3 8.31e-9 Metabolite levels; LIHC cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1538970 0.924 rs7528573 chr1:45913860 T/C cg05343316 chr1:45956843 TESK2 0.58 8.49 0.42 6.45e-16 Platelet count; LIHC cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg06481639 chr22:41940642 POLR3H 0.71 7.37 0.37 1.29e-12 Vitiligo; LIHC cis rs652260 1.000 rs590394 chr19:7902505 C/T cg26014689 chr19:7917955 EVI5L -0.66 -11.66 -0.53 1.16e-26 Menarche (age at onset); LIHC cis rs7954584 0.520 rs1169094 chr12:122465535 A/G cg22618164 chr12:122356400 WDR66 -0.46 -7.59 -0.38 3.03e-13 Mean corpuscular volume; LIHC cis rs963731 0.649 rs297130 chr2:39299314 C/T cg04010122 chr2:39346883 SOS1 0.69 6.28 0.32 1.05e-9 Corticobasal degeneration; LIHC cis rs651907 0.535 rs11712309 chr3:101519097 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs4654899 1.000 rs6426659 chr1:21361302 G/A cg08539965 chr1:21396338 EIF4G3 0.33 5.74 0.3 2.07e-8 Superior frontal gyrus grey matter volume; LIHC cis rs597539 0.652 rs604524 chr11:68629929 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.78 11.64 0.53 1.34e-26 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs9641123 0.580 rs2051748 chr7:93199574 A/G cg09745688 chr16:2908918 PRSS22 -0.37 -6.34 -0.32 7.31e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs7582720 0.778 rs6719001 chr2:203777903 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9443189 0.526 rs775060 chr6:76373567 G/A cg01950844 chr6:76311363 SENP6 -0.87 -10.84 -0.51 9.96e-24 Prostate cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26175033 chr2:43037432 NA -0.42 -6.36 -0.33 6.38e-10 Pancreatic cancer; LIHC cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg18279126 chr7:2041391 MAD1L1 0.37 6.1 0.31 2.88e-9 Bipolar disorder and schizophrenia; LIHC cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg12373951 chr3:133503437 NA 0.45 7.54 0.38 4.18e-13 Iron status biomarkers; LIHC cis rs72781680 0.898 rs6712175 chr2:24023431 T/G cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs13223928 0.651 rs4722426 chr7:3150697 C/T cg19214707 chr7:3157722 NA 0.42 7.96 0.4 2.57e-14 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg02034447 chr16:89574710 SPG7 0.5 7.69 0.38 1.61e-13 Multiple myeloma (IgH translocation); LIHC cis rs507080 0.922 rs502601 chr11:118565679 G/A cg04173919 chr11:118528438 PHLDB1 0.36 6.62 0.34 1.43e-10 Serum metabolite levels; LIHC cis rs9549367 0.789 rs2287244 chr13:113887173 C/G cg18105134 chr13:113819100 PROZ 0.56 9.99 0.48 8.49e-21 Platelet distribution width; LIHC cis rs6430585 0.528 rs6743537 chr2:136702601 C/T cg07169764 chr2:136633963 MCM6 1.19 18.29 0.7 1.36e-52 Corneal structure; LIHC cis rs4819052 0.851 rs2838826 chr21:46655785 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.66 9.49 0.46 4.13e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs853679 0.517 rs1904841 chr6:28108085 C/T cg16479474 chr6:28041457 NA 0.45 6.4 0.33 5.05e-10 Depression; LIHC cis rs208515 0.525 rs10944869 chr6:66687576 G/T cg07460842 chr6:66804631 NA 0.77 8.91 0.43 2.99e-17 Exhaled nitric oxide levels; LIHC cis rs919433 0.679 rs6757669 chr2:198530355 C/T cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs11098499 0.863 rs1480936 chr4:120462861 C/T cg25214090 chr10:38739885 LOC399744 0.61 9.85 0.47 2.6e-20 Corneal astigmatism; LIHC cis rs4595586 0.563 rs11169769 chr12:39233134 C/G cg26384229 chr12:38710491 ALG10B 0.53 6.97 0.35 1.6e-11 Morning vs. evening chronotype; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01110552 chr10:103578627 MGEA5 0.46 7.04 0.36 1.06e-11 Pancreatic cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg25193742 chr10:104614220 C10orf32 0.4 6.1 0.31 2.92e-9 Calcium levels; LIHC cis rs1865760 0.622 rs9968910 chr6:26072095 A/C cg17691542 chr6:26056736 HIST1H1C 0.62 8.18 0.4 5.58e-15 Height; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18710692 chr13:20437712 ZMYM5 -0.53 -6.17 -0.32 1.97e-9 Systolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19640263 chr11:62414186 GANAB -0.44 -6.17 -0.32 1.91e-9 Pancreatic cancer; LIHC cis rs12474201 0.889 rs2346878 chr2:46922870 C/T cg06386533 chr2:46925753 SOCS5 0.6 6.9 0.35 2.49e-11 Height; LIHC cis rs2479724 0.901 rs33954419 chr6:41786136 A/G cg17623882 chr6:41773611 USP49 -0.56 -9.02 -0.44 1.34e-17 Menarche (age at onset); LIHC cis rs34779708 0.966 rs35079558 chr10:35479886 A/G cg03585969 chr10:35415529 CREM 0.87 13.07 0.58 6.35e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs807029 0.577 rs11190787 chr10:102758625 G/T cg25179470 chr10:102756915 LZTS2 0.45 6.26 0.32 1.15e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4975709 0.589 rs4975745 chr5:1861058 G/C cg15595755 chr5:1867978 NA 0.4 8.12 0.4 8.38e-15 Cardiovascular disease risk factors; LIHC cis rs9399135 0.933 rs9389262 chr6:135376409 G/T cg24558204 chr6:135376177 HBS1L 0.44 7.21 0.36 3.62e-12 Red blood cell count; LIHC cis rs12478296 1.000 rs59036157 chr2:243040228 C/A cg05760424 chr2:242988095 NA -0.5 -6.69 -0.34 9.22e-11 Obesity-related traits; LIHC cis rs4407350 0.870 rs1894461 chr22:44911287 C/T cg11695653 chr22:44894386 LDOC1L -0.36 -6.06 -0.31 3.69e-9 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.45 6.22 0.32 1.48e-9 Schizophrenia; LIHC cis rs4742903 0.935 rs17236663 chr9:106928402 G/A cg14250997 chr9:106856677 SMC2 0.36 6.02 0.31 4.43e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs11077998 0.967 rs901373 chr17:80506559 A/G cg10255544 chr17:80519551 FOXK2 0.5 8.92 0.43 2.88e-17 Reticulocyte fraction of red cells; LIHC cis rs10916814 1.000 rs4654863 chr1:20902244 G/A cg24502330 chr1:20914028 CDA -0.28 -5.88 -0.3 9.72e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs8062405 0.723 rs4788079 chr16:28559363 C/A cg00204512 chr16:28754710 NA 0.41 7.22 0.36 3.41e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11792861 0.591 rs10979632 chr9:111732140 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.7 11.67 0.53 1.03e-26 Menarche (age at onset); LIHC cis rs2404602 0.684 rs2047504 chr15:76883516 A/T cg03037974 chr15:76606532 NA -0.61 -10.2 -0.48 1.73e-21 Blood metabolite levels; LIHC cis rs7927592 0.913 rs10896338 chr11:68299360 G/A cg16797656 chr11:68205561 LRP5 0.51 8.1 0.4 9.54e-15 Total body bone mineral density; LIHC cis rs523522 0.962 rs4767905 chr12:120930835 C/T cg12219531 chr12:120966889 COQ5 0.67 13.3 0.58 7.99e-33 High light scatter reticulocyte count; LIHC cis rs16958440 0.867 rs117060920 chr18:44709035 G/A cg17192377 chr18:44677553 HDHD2 0.86 8.02 0.4 1.71e-14 Sitting height ratio; LIHC cis rs826838 0.935 rs11169511 chr12:39175802 T/C cg26384229 chr12:38710491 ALG10B 0.86 11.16 0.52 7.1e-25 Heart rate; LIHC cis rs9322193 0.923 rs4869750 chr6:150177132 C/T cg05036130 chr6:150231994 NA 0.36 5.97 0.31 5.83e-9 Lung cancer; LIHC cis rs10744422 0.858 rs2292136 chr12:123339344 A/G cg07706471 chr12:123319906 HIP1R -0.63 -8.28 -0.41 2.88e-15 Schizophrenia; LIHC cis rs1499614 0.803 rs1922723 chr7:66175063 C/T cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC trans rs11165623 0.792 rs6701031 chr1:96975515 C/T cg10631902 chr5:14652156 NA -0.32 -7.5 -0.38 5.53e-13 Hip circumference;Waist circumference; LIHC cis rs7474896 0.616 rs2505239 chr10:38440765 A/G cg25427524 chr10:38739819 LOC399744 -0.5 -6.65 -0.34 1.18e-10 Obesity (extreme); LIHC cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg00035636 chr13:21900591 NA 0.37 6.05 0.31 3.71e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs240764 0.578 rs1414734 chr6:101201823 T/C cg12253828 chr6:101329408 ASCC3 0.42 6.7 0.34 8.81e-11 Neuroticism; LIHC cis rs2976388 0.524 rs7012804 chr8:143844650 A/G cg06565975 chr8:143823917 SLURP1 0.38 7.35 0.37 1.46e-12 Urinary tract infection frequency; LIHC cis rs2637030 0.502 rs1844698 chr5:52970339 G/A cg06476337 chr5:52856530 NDUFS4 0.43 6.8 0.35 4.68e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs7589728 0.563 rs79892776 chr2:88470593 G/A cg14558114 chr2:88469736 THNSL2 0.59 5.78 0.3 1.64e-8 Plasma clusterin levels; LIHC cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg16262614 chr3:133464971 TF 0.27 6.03 0.31 4.21e-9 Iron status biomarkers; LIHC cis rs1801251 1.000 rs10933412 chr2:233707226 G/C cg25237894 chr2:233734115 C2orf82 -0.59 -11.48 -0.53 5.08e-26 Coronary artery disease; LIHC cis rs7487075 0.780 rs10785624 chr12:46766787 C/T cg22049899 chr12:47219821 SLC38A4 0.36 6.15 0.32 2.16e-9 Itch intensity from mosquito bite; LIHC cis rs7296418 0.961 rs11608811 chr12:123529056 A/G cg05973401 chr12:123451056 ABCB9 0.53 8.4 0.41 1.2e-15 Platelet count; LIHC cis rs17826219 0.500 rs61685770 chr17:29085713 G/A cg14067834 chr17:29058358 SUZ12P 0.69 6.86 0.35 3.31e-11 Body mass index; LIHC cis rs3008870 1.000 rs2985795 chr1:67426223 A/G cg02640540 chr1:67518911 SLC35D1 0.43 5.93 0.31 7.24e-9 Lymphocyte percentage of white cells; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03993171 chr6:86388501 SNORD50B;SNORD50A;SNHG5 0.43 6.73 0.34 6.98e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs6120849 0.617 rs12480442 chr20:33648388 C/G cg24642439 chr20:33292090 TP53INP2 0.66 7.19 0.36 4.1e-12 Protein C levels; LIHC cis rs11098499 0.569 rs10023641 chr4:120258410 C/G cg09307838 chr4:120376055 NA 0.62 9.87 0.47 2.26e-20 Corneal astigmatism; LIHC cis rs7712401 0.755 rs10071705 chr5:122132725 T/C cg18764291 chr5:122110994 SNX2 0.37 6.28 0.32 1.01e-9 Mean platelet volume; LIHC cis rs2642442 0.962 rs2642439 chr1:220970499 C/T cg04704887 chr1:220970030 MOSC1 0.44 5.94 0.31 6.99e-9 Cholesterol, total;LDL cholesterol; LIHC cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg27170947 chr2:26402098 FAM59B 0.66 8.33 0.41 2.01e-15 Gut microbiome composition (summer); LIHC cis rs807029 0.533 rs3740486 chr10:102750623 T/C cg17130504 chr10:102756923 LZTS2 0.56 7.78 0.39 8.74e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2153535 0.580 rs7747306 chr6:8453663 C/G cg07606381 chr6:8435919 SLC35B3 -0.78 -11.6 -0.53 1.92e-26 Motion sickness; LIHC cis rs7647973 0.626 rs1996663 chr3:49878264 C/G cg03060546 chr3:49711283 APEH -0.59 -6.94 -0.35 2e-11 Menarche (age at onset); LIHC cis rs754466 0.580 rs1058198 chr10:79566632 G/A cg17075019 chr10:79541650 NA -0.75 -11.43 -0.53 7.65e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs9929218 0.551 rs8051095 chr16:68722049 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.93 22.84 0.78 9.22e-71 Colorectal cancer; LIHC cis rs4727027 0.870 rs11524138 chr7:148799125 G/A cg23583168 chr7:148888333 NA -0.7 -9.89 -0.47 1.83e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11878675 chr2:74211845 NA 0.63 8.39 0.41 1.33e-15 Lung function (FEV1/FVC); LIHC cis rs477895 0.838 rs1058735 chr11:64000410 C/G cg05555928 chr11:63887634 MACROD1 0.46 6.02 0.31 4.41e-9 Mean platelet volume; LIHC cis rs7246657 0.943 rs10415024 chr19:37814724 A/G cg23950597 chr19:37808831 NA -0.56 -7.32 -0.37 1.77e-12 Coronary artery calcification; LIHC cis rs17106184 1.000 rs72898953 chr1:50963858 T/C cg07174182 chr1:51127561 FAF1 -0.59 -6.61 -0.34 1.47e-10 Type 2 diabetes; LIHC cis rs10791323 0.628 rs4937838 chr11:133733406 T/C cg15485101 chr11:133734466 NA 0.26 6.28 0.32 1.06e-9 Childhood ear infection; LIHC trans rs3748022 1.000 rs12124627 chr1:206687263 C/G cg10512875 chr12:29936174 TMTC1 -0.46 -6.14 -0.32 2.32e-9 Lymphocyte counts; LIHC cis rs8049040 0.500 rs7188475 chr16:71446358 C/T cg06353428 chr16:71660113 MARVELD3 -0.56 -6.32 -0.32 7.95e-10 Blood protein levels; LIHC cis rs5758659 0.692 rs5751251 chr22:42640606 G/C cg19513890 chr22:42538836 CYP2D7P1 -0.31 -5.93 -0.31 7.29e-9 Cognitive function; LIHC cis rs11628318 0.853 rs8003309 chr14:103050143 C/G cg12046867 chr14:103022105 NA -0.58 -8.27 -0.41 2.99e-15 Platelet count; LIHC cis rs738321 0.725 rs9622738 chr22:38542346 G/A cg25457927 chr22:38595422 NA -0.35 -7.92 -0.39 3.42e-14 Breast cancer; LIHC cis rs9616064 0.506 rs6008944 chr22:47060976 C/T cg25730555 chr22:47059586 GRAMD4 0.36 6.14 0.32 2.27e-9 Urate levels in obese individuals; LIHC cis rs6504950 0.720 rs2877634 chr17:52987545 A/G cg10237252 chr17:52977213 TOM1L1 -0.37 -6.42 -0.33 4.58e-10 Breast cancer; LIHC cis rs3814244 0.528 rs56393928 chr12:68423707 A/G cg15249341 chr12:68405565 NA -0.3 -5.81 -0.3 1.46e-8 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs6840360 0.533 rs13119490 chr4:152713412 A/G cg22705602 chr4:152727874 NA 0.39 8.11 0.4 9.38e-15 Intelligence (multi-trait analysis); LIHC cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg03396347 chr1:1875803 NA -0.47 -8.77 -0.43 8.4e-17 Body mass index; LIHC cis rs6570726 0.791 rs1509213 chr6:145783360 G/A cg23711669 chr6:146136114 FBXO30 -0.68 -11.01 -0.51 2.54e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.778 rs4970766 chr1:110013955 A/G cg23091122 chr1:110024289 SYPL2 0.45 6.22 0.32 1.48e-9 Intelligence (multi-trait analysis); LIHC cis rs2576037 0.526 rs9304340 chr18:44526582 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.46 0.49 2.07e-22 Personality dimensions; LIHC cis rs4689592 0.587 rs6825954 chr4:7074226 T/C cg02503808 chr4:7069936 GRPEL1 0.79 11.6 0.53 1.77e-26 Monocyte percentage of white cells; LIHC cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg15691649 chr6:25882328 NA -0.46 -5.79 -0.3 1.56e-8 Intelligence (multi-trait analysis); LIHC cis rs7107174 1.000 rs10793302 chr11:78040961 C/T cg02023728 chr11:77925099 USP35 0.48 9.23 0.45 2.94e-18 Testicular germ cell tumor; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14727059 chr3:53195316 PRKCD -0.54 -6.26 -0.32 1.17e-9 Systolic blood pressure; LIHC cis rs10744422 0.528 rs6489245 chr12:123360151 G/A cg18912006 chr12:123335444 HIP1R -0.59 -6.54 -0.33 2.23e-10 Schizophrenia; LIHC cis rs10744422 1.000 rs4993320 chr12:123338092 T/C cg25930673 chr12:123319894 HIP1R -0.96 -12.76 -0.57 9.14e-31 Schizophrenia; LIHC cis rs7552404 0.924 rs1858536 chr1:76161595 G/T cg03433033 chr1:76189801 ACADM 0.69 10.58 0.5 8e-23 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg26874164 chr19:58962979 ZNF324B 0.6 9.31 0.45 1.54e-18 Uric acid clearance; LIHC cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg07424592 chr7:64974309 NA 0.82 9.64 0.46 1.27e-19 Diabetic kidney disease; LIHC cis rs2304069 0.955 rs4288106 chr5:149394872 A/G cg12661370 chr5:149340060 SLC26A2 0.49 5.99 0.31 5.3e-9 HIV-1 control; LIHC cis rs736408 0.608 rs35004449 chr3:52852897 G/T cg18404041 chr3:52824283 ITIH1 -0.43 -6.21 -0.32 1.51e-9 Bipolar disorder; LIHC cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg05590025 chr7:65112418 INTS4L2 -0.65 -7.03 -0.36 1.1e-11 Diabetic kidney disease; LIHC trans rs1499614 1.000 rs2659903 chr7:66180931 G/A cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs2455799 0.613 rs13096622 chr3:15837656 A/G cg12698662 chr3:15914712 MIR563 -0.4 -7.48 -0.37 6.36e-13 Mean platelet volume; LIHC cis rs10416265 0.502 rs7245411 chr19:33543029 A/T cg17764715 chr19:33622953 WDR88 0.56 7.53 0.38 4.51e-13 Bone properties (heel); LIHC trans rs1814175 0.791 rs11040513 chr11:49778153 G/C cg03929089 chr4:120376271 NA -0.9 -18.39 -0.71 5.32e-53 Height; LIHC cis rs2386661 0.523 rs7896088 chr10:5652286 C/T cg17085576 chr10:5658249 NA -0.3 -5.85 -0.3 1.15e-8 Breast cancer; LIHC cis rs748404 0.588 rs2255410 chr15:43831097 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.37 6.08 0.31 3.15e-9 Lung cancer; LIHC cis rs4728302 0.869 rs10155909 chr7:133593036 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.52 0.33 2.46e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs6547741 0.816 rs7560847 chr2:27882700 A/G cg27432699 chr2:27873401 GPN1 -0.93 -16.37 -0.66 7.08e-45 Oral cavity cancer; LIHC cis rs9304742 1.000 rs9304742 chr19:53451291 A/G cg01285391 chr19:53465759 ZNF816A -0.32 -5.75 -0.3 2e-8 Psoriasis; LIHC cis rs3096299 0.933 rs3114848 chr16:89452771 G/A cg00750074 chr16:89608354 SPG7 -0.4 -6.21 -0.32 1.58e-9 Multiple myeloma (IgH translocation); LIHC cis rs61990749 0.686 rs11159288 chr14:78216972 G/A cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.75 -0.39 1.02e-13 Fibroblast growth factor basic levels; LIHC trans rs1005277 0.522 rs1208681 chr10:38092975 C/T cg17830980 chr10:43048298 ZNF37B -0.43 -8.36 -0.41 1.62e-15 Extrinsic epigenetic age acceleration; LIHC cis rs116095464 0.558 rs62347683 chr5:230331 C/T cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg21003380 chr1:156261207 TMEM79 0.36 5.78 0.3 1.72e-8 Tonsillectomy; LIHC cis rs12497850 0.931 rs13064784 chr3:49135961 C/G cg06212747 chr3:49208901 KLHDC8B 0.6 7.86 0.39 5.1e-14 Parkinson's disease; LIHC cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.84 0.3 1.21e-8 Menopause (age at onset); LIHC cis rs6952808 0.929 rs1801368 chr7:1976457 C/T cg21782813 chr7:2030301 MAD1L1 0.47 8.05 0.4 1.42e-14 Bipolar disorder and schizophrenia; LIHC cis rs1059312 0.545 rs12303387 chr12:129276733 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.5 7.62 0.38 2.59e-13 Systemic lupus erythematosus; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09352908 chr3:37017749 NA 0.42 6.23 0.32 1.4e-9 Pancreatic cancer; LIHC cis rs66573146 1.000 rs56074877 chr4:6990374 C/T cg00086871 chr4:6988644 TBC1D14 0.88 6.0 0.31 5.03e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs12602486 1.000 rs16940539 chr17:42224581 C/G cg08193365 chr17:42277699 NA 1.09 7.72 0.39 1.27e-13 Glycated hemoglobin levels; LIHC cis rs600806 0.778 rs4970765 chr1:110009171 C/T cg10127483 chr1:110009974 SYPL2 0.48 6.06 0.31 3.53e-9 Intelligence (multi-trait analysis); LIHC cis rs7613875 0.580 rs6808044 chr3:50136165 A/G cg05623727 chr3:50126028 RBM5 -0.35 -6.08 -0.31 3.25e-9 Body mass index; LIHC cis rs17376456 0.825 rs10054790 chr5:93272520 A/G cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs72627123 0.867 rs74635757 chr14:74489225 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.92 9.76 0.47 5.28e-20 Morning vs. evening chronotype; LIHC cis rs7937890 0.900 rs7118682 chr11:14274550 T/G cg06199346 chr11:14280333 SPON1 0.35 5.86 0.3 1.07e-8 Mitochondrial DNA levels; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg20295408 chr7:1910781 MAD1L1 -0.42 -6.08 -0.31 3.17e-9 Bipolar disorder and schizophrenia; LIHC cis rs6840360 0.615 rs9884167 chr4:152470799 A/G cg22705602 chr4:152727874 NA -0.33 -6.45 -0.33 3.85e-10 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.538 rs6454483 chr6:86418283 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.47 9.31 0.45 1.61e-18 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs763121 0.853 rs6519120 chr22:38991393 A/C cg06022373 chr22:39101656 GTPBP1 -0.67 -11.5 -0.53 4.42e-26 Menopause (age at onset); LIHC cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -14.0 -0.6 1.66e-35 Alzheimer's disease; LIHC cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg09455208 chr3:40491958 NA 0.34 6.78 0.34 5.26e-11 Renal cell carcinoma; LIHC cis rs4700695 0.719 rs1643415 chr5:65447087 T/C cg21114390 chr5:65439923 SFRS12 -0.58 -8.37 -0.41 1.46e-15 Facial morphology (factor 19); LIHC trans rs2710642 0.564 rs7558681 chr2:62840987 G/A cg23713900 chr18:615496 CLUL1 -0.23 -6.05 -0.31 3.86e-9 LDL cholesterol levels;LDL cholesterol; LIHC cis rs12477438 0.520 rs6542864 chr2:99725223 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 13.98 0.6 1.94e-35 Chronic sinus infection; LIHC cis rs6952808 0.825 rs4236277 chr7:1942270 C/T cg02951883 chr7:2050386 MAD1L1 -0.62 -9.24 -0.45 2.68e-18 Bipolar disorder and schizophrenia; LIHC cis rs13108904 0.870 rs2291199 chr4:1244267 A/G cg00684032 chr4:1343700 KIAA1530 0.49 6.94 0.35 2.02e-11 Obesity-related traits; LIHC cis rs561341 0.824 rs1978115 chr17:30220776 A/C cg13647721 chr17:30228624 UTP6 0.8 7.74 0.39 1.17e-13 Hip circumference adjusted for BMI; LIHC cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg10360139 chr7:1886902 MAD1L1 -0.4 -6.18 -0.32 1.77e-9 Bipolar disorder and schizophrenia; LIHC cis rs6831352 0.879 rs2851255 chr4:100042103 C/G cg12011299 chr4:100065546 ADH4 0.57 9.61 0.46 1.59e-19 Alcohol dependence; LIHC cis rs7520050 0.966 rs4660319 chr1:46341623 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs17401966 0.522 rs17396973 chr1:10334924 C/T cg19773385 chr1:10388646 KIF1B -0.33 -6.05 -0.31 3.91e-9 Hepatocellular carcinoma; LIHC cis rs6500602 0.727 rs1477123 chr16:4560627 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.56 8.63 0.42 2.27e-16 Schizophrenia; LIHC cis rs11098499 0.863 rs10004484 chr4:120442428 C/T cg09307838 chr4:120376055 NA 0.76 11.6 0.53 1.88e-26 Corneal astigmatism; LIHC cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.57 9.63 0.46 1.43e-19 Bipolar disorder; LIHC cis rs1538970 0.924 rs3790582 chr1:45887288 T/C cg05343316 chr1:45956843 TESK2 0.57 8.38 0.41 1.37e-15 Platelet count; LIHC cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs8177253 1.000 rs6762719 chr3:133480817 A/G cg12373951 chr3:133503437 NA 0.69 12.44 0.56 1.41e-29 Iron status biomarkers; LIHC cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg06634786 chr22:41940651 POLR3H -0.8 -8.56 -0.42 3.83e-16 Vitiligo; LIHC cis rs9309473 0.607 rs4641966 chr2:73590806 G/A cg20560298 chr2:73613845 ALMS1 -0.44 -7.0 -0.35 1.39e-11 Metabolite levels; LIHC cis rs6831352 0.959 rs6532796 chr4:100042242 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.78 -0.5 1.65e-23 Alcohol dependence; LIHC cis rs11673344 0.764 rs10424584 chr19:37466888 G/A cg27390819 chr19:37464633 NA -0.49 -5.87 -0.3 1.05e-8 Obesity-related traits; LIHC trans rs11098499 0.604 rs10022185 chr4:120571765 C/G cg25214090 chr10:38739885 LOC399744 0.54 8.44 0.42 9.12e-16 Corneal astigmatism; LIHC cis rs765787 0.530 rs2413785 chr15:45530381 T/C cg25801113 chr15:45476975 SHF 0.37 6.36 0.33 6.62e-10 Uric acid levels; LIHC cis rs60871478 1.000 rs62432860 chr7:807522 G/C cg05535760 chr7:792225 HEATR2 0.79 11.2 0.52 5.04e-25 Cerebrospinal P-tau181p levels; LIHC cis rs1552244 0.554 rs3732964 chr3:10048839 C/G cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs2839186 0.967 rs2839191 chr21:47695395 C/G cg09417038 chr21:47716443 C21orf57 -0.5 -7.35 -0.37 1.5e-12 Testicular germ cell tumor; LIHC cis rs1215050 0.527 rs1214998 chr4:99042878 T/G cg05340658 chr4:99064831 C4orf37 0.42 6.58 0.34 1.73e-10 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10869376 chr13:41345315 MRPS31 0.44 6.26 0.32 1.14e-9 Pancreatic cancer; LIHC cis rs3809863 0.602 rs2317677 chr17:45393407 G/A cg25173405 chr17:45401733 C17orf57 -0.58 -8.6 -0.42 2.86e-16 Glaucoma (primary open-angle); LIHC cis rs754466 0.651 rs10824584 chr10:79625947 G/A cg17075019 chr10:79541650 NA -0.75 -11.49 -0.53 4.54e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2067615 0.579 rs1922438 chr12:107085171 C/G cg15890332 chr12:107067104 RFX4 0.26 6.18 0.32 1.81e-9 Heart rate; LIHC cis rs7552404 0.690 rs2029681 chr1:76333846 G/A cg03433033 chr1:76189801 ACADM -0.53 -6.57 -0.33 1.83e-10 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs12477438 0.765 rs62154861 chr2:99590235 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.09 -15.97 -0.65 2.73e-43 Chronic sinus infection; LIHC cis rs9916302 0.904 rs602688 chr17:37439496 C/T cg03013999 chr17:37608204 MED1 0.34 5.75 0.3 1.97e-8 Glomerular filtration rate (creatinine); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04980793 chr14:35451984 SRP54 0.43 6.34 0.32 7.28e-10 Lung function (FEV1/FVC); LIHC cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg16145915 chr7:1198662 ZFAND2A -0.34 -8.31 -0.41 2.31e-15 Longevity;Endometriosis; LIHC cis rs787274 1.000 rs4979150 chr9:115553502 T/A cg13803584 chr9:115635662 SNX30 -0.6 -6.68 -0.34 9.69e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2279817 0.908 rs3766310 chr1:17977642 A/C cg21791023 chr1:18019539 ARHGEF10L -0.62 -7.04 -0.36 1.03e-11 Neuroticism; LIHC cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg04546413 chr19:29218101 NA 0.56 10.36 0.49 4.79e-22 Methadone dose in opioid dependence; LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.9 -0.3 8.51e-9 Total body bone mineral density; LIHC cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg03517284 chr6:25882590 NA 0.88 11.71 0.53 7.59e-27 Blood metabolite levels; LIHC cis rs11583043 0.918 rs11581062 chr1:101407519 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.62 -8.78 -0.43 7.98e-17 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs5769765 0.773 rs11090920 chr22:50320105 A/G cg02269571 chr22:50332266 NA -0.67 -9.06 -0.44 1.03e-17 Schizophrenia; LIHC cis rs116095464 0.558 rs6879656 chr5:264428 T/C cg22857025 chr5:266934 NA -1.52 -17.08 -0.68 1e-47 Breast cancer; LIHC cis rs875971 0.660 rs801211 chr7:66015689 T/G cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC cis rs17253792 0.822 rs8009608 chr14:56062590 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg03517284 chr6:25882590 NA 0.52 6.82 0.35 4.23e-11 Intelligence (multi-trait analysis); LIHC cis rs7945718 0.621 rs6485978 chr11:12678415 T/C cg25843174 chr11:12811716 TEAD1 0.33 7.79 0.39 8.06e-14 Educational attainment (years of education); LIHC cis rs7224737 0.957 rs6503687 chr17:40295397 G/A cg02450064 chr17:40260053 DHX58 -0.3 -6.14 -0.32 2.24e-9 Fibrinogen levels; LIHC cis rs2153535 0.580 rs9393019 chr6:8462091 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.21e-16 Motion sickness; LIHC cis rs7103648 0.545 rs6485795 chr11:47929846 G/A cg20307385 chr11:47447363 PSMC3 0.96 14.2 0.61 2.67e-36 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs9596863 0.821 rs4884722 chr13:54429821 C/A ch.13.53330881F chr13:54432880 NA -0.43 -5.97 -0.31 6.08e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs13191362 1.000 rs35103567 chr6:163183400 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.84 6.65 0.34 1.14e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10911232 0.507 rs61081633 chr1:182995608 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs4423214 0.625 rs78685409 chr11:71137383 T/C cg24826892 chr11:71159390 DHCR7 -0.46 -5.86 -0.3 1.06e-8 Vitamin D levels; LIHC cis rs9549367 0.577 rs3024713 chr13:113813321 G/A cg00898013 chr13:113819073 PROZ -0.44 -6.72 -0.34 7.61e-11 Platelet distribution width; LIHC cis rs941873 0.805 rs8837 chr10:81114813 C/G cg09469691 chr10:81107165 PPIF 0.68 10.24 0.48 1.19e-21 Height; LIHC cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs7520050 0.966 rs6672898 chr1:46290588 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.08 0.31 3.26e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7208859 0.623 rs79607958 chr17:28934548 T/G cg13385521 chr17:29058706 SUZ12P 0.7 6.72 0.34 7.7e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1707322 0.752 rs28568986 chr1:46207743 C/T cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg22903471 chr2:27725779 GCKR -0.48 -8.22 -0.41 4.17e-15 Menopause (age at onset); LIHC cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg24250549 chr1:154909240 PMVK 0.67 10.56 0.5 9.86e-23 Prostate cancer; LIHC cis rs801193 1.000 rs2707836 chr7:66160435 A/C cg00343986 chr7:65444356 GUSB 0.39 5.77 0.3 1.76e-8 Aortic root size; LIHC cis rs34779708 0.931 rs1926556 chr10:35344907 T/C cg03585969 chr10:35415529 CREM 0.86 12.99 0.57 1.26e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7772486 0.875 rs2328712 chr6:146344563 T/C cg13319975 chr6:146136371 FBXO30 -0.34 -5.79 -0.3 1.62e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9948 0.786 rs6756482 chr2:97458561 A/G cg01990225 chr2:97406019 LMAN2L -0.73 -6.79 -0.34 5.04e-11 Erectile dysfunction and prostate cancer treatment; LIHC cis rs6456156 0.586 rs6456150 chr6:167468922 A/G cg12798992 chr6:167411361 FGFR1OP 0.44 6.77 0.34 5.73e-11 Primary biliary cholangitis; LIHC cis rs2084898 0.891 rs504976 chr11:120000233 C/A cg13907859 chr11:120009124 TRIM29 -0.53 -6.53 -0.33 2.39e-10 Stroke (pediatric); LIHC cis rs2404602 0.622 rs1567671 chr15:77209200 C/G cg23625390 chr15:77176239 SCAPER -0.48 -8.03 -0.4 1.6e-14 Blood metabolite levels; LIHC cis rs6061231 0.624 rs8668 chr20:60964064 C/T cg03945807 chr20:60948434 NA -0.41 -6.81 -0.35 4.4e-11 Colorectal cancer; LIHC cis rs1552244 0.515 rs67626468 chr3:10161518 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs72627123 0.867 rs73301477 chr14:74463560 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.6 0.42 2.96e-16 Morning vs. evening chronotype; LIHC cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg24879335 chr3:133465180 TF 0.27 5.83 0.3 1.25e-8 Iron status biomarkers; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08536481 chr12:123459152 ABCB9;OGFOD2 -0.38 -6.29 -0.32 9.94e-10 Longevity; LIHC trans rs1005277 0.579 rs2800485 chr10:38542588 G/A cg23533926 chr12:111358616 MYL2 -0.36 -6.86 -0.35 3.18e-11 Extrinsic epigenetic age acceleration; LIHC cis rs17539620 0.624 rs62432738 chr6:154835674 T/C cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC cis rs7224737 1.000 rs11079034 chr17:40288890 G/A cg20291162 chr17:40259547 DHX58 -0.4 -6.35 -0.32 7.05e-10 Fibrinogen levels; LIHC trans rs4942242 0.763 rs7327129 chr13:44233014 T/C cg19169023 chr15:41853346 TYRO3 -0.45 -6.59 -0.34 1.71e-10 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs7903847 0.642 rs1537645 chr10:99149914 T/C cg06359132 chr10:99160096 RRP12 -0.41 -6.4 -0.33 5.18e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2404602 1.000 rs12898430 chr15:76874923 G/A cg03037974 chr15:76606532 NA 0.71 13.75 0.6 1.53e-34 Blood metabolite levels; LIHC cis rs34779708 0.966 rs6481941 chr10:35440141 G/A cg03585969 chr10:35415529 CREM 0.79 11.81 0.54 3.14e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2115630 0.905 rs1975277 chr15:85329558 C/T cg11189052 chr15:85197271 WDR73 -0.38 -5.75 -0.3 1.94e-8 P wave terminal force; LIHC cis rs875971 1.000 rs1981798 chr7:65954903 G/T cg18876405 chr7:65276391 NA 0.38 6.86 0.35 3.16e-11 Aortic root size; LIHC cis rs34172651 0.517 rs11862923 chr16:24767303 G/T cg00152838 chr16:24741724 TNRC6A -0.51 -6.3 -0.32 9.08e-10 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg16145915 chr7:1198662 ZFAND2A -0.4 -10.15 -0.48 2.53e-21 Longevity;Endometriosis; LIHC cis rs875971 0.964 rs778735 chr7:65814809 C/A cg11764359 chr7:65958608 NA 0.92 17.11 0.68 7.76e-48 Aortic root size; LIHC cis rs780096 0.546 rs12473776 chr2:27636474 A/G cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.21 -0.32 1.5e-9 Total body bone mineral density; LIHC cis rs10848704 1.000 rs10848704 chr12:2882544 A/G cg19995117 chr12:2880862 NA -0.35 -5.94 -0.31 6.91e-9 Quantitative traits; LIHC cis rs858239 0.669 rs1006709 chr7:23140099 C/T cg23682824 chr7:23144976 KLHL7 0.41 6.31 0.32 8.43e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.95 8.47 0.42 7.2e-16 Platelet count; LIHC cis rs4423214 0.840 rs1792226 chr11:71176574 C/T cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg05481257 chr2:20870211 GDF7 -0.43 -8.1 -0.4 9.66e-15 Abdominal aortic aneurysm; LIHC cis rs9326248 1.000 rs585849 chr11:117069061 A/G cg01368799 chr11:117014884 PAFAH1B2 0.41 5.75 0.3 1.99e-8 Blood protein levels; LIHC cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg18306943 chr3:40428807 ENTPD3 -0.4 -7.17 -0.36 4.67e-12 Renal cell carcinoma; LIHC trans rs13325613 0.915 rs34289272 chr3:46263244 C/T cg26337592 chr1:153642686 ILF2 0.68 6.2 0.32 1.66e-9 Monocyte count; LIHC cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg04025307 chr7:1156635 C7orf50 0.55 8.9 0.43 3.4e-17 Longevity;Endometriosis; LIHC cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg07414643 chr4:187882934 NA 0.23 5.86 0.3 1.1e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg00166722 chr3:10149974 C3orf24 0.48 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC cis rs4294134 1.000 rs4294134 chr7:135293128 A/G cg20392616 chr7:135392013 SLC13A4 -0.4 -6.57 -0.33 1.88e-10 Paget's disease; LIHC cis rs2304069 0.954 rs216125 chr5:149428395 C/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.93 11.47 0.53 5.44e-26 HIV-1 control; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11079354 chr6:27740361 NA 0.42 6.93 0.35 2.07e-11 Cognitive function; LIHC cis rs2153535 0.541 rs1414347 chr6:8471831 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.47 -7.47 -0.37 6.86e-13 Prudent dietary pattern; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg22081355 chr19:17186472 HAUS8;MYO9B -0.56 -6.26 -0.32 1.17e-9 Systolic blood pressure; LIHC cis rs9783347 0.961 rs4150526 chr11:18343209 G/A cg15585147 chr11:18324498 HPS5 0.43 6.65 0.34 1.18e-10 Pancreatic cancer; LIHC cis rs2302190 1.000 rs2302190 chr17:56584508 A/G cg12560992 chr17:57184187 TRIM37 0.69 9.09 0.44 8.27e-18 Vitamin D levels; LIHC cis rs1005277 0.579 rs2474569 chr10:38383491 C/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs6963495 0.745 rs73192153 chr7:105212418 A/T cg19920283 chr7:105172520 RINT1 0.66 5.94 0.31 6.91e-9 Bipolar disorder (body mass index interaction); LIHC cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.76 7.45 0.37 7.54e-13 Platelet count; LIHC cis rs7769051 1.000 rs12204027 chr6:133122831 A/G cg22852734 chr6:133119734 C6orf192 0.96 9.45 0.45 5.74e-19 Type 2 diabetes nephropathy; LIHC cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs16958440 0.867 rs79275306 chr18:44711620 G/C cg17192377 chr18:44677553 HDHD2 0.91 8.68 0.42 1.64e-16 Sitting height ratio; LIHC cis rs7618501 0.601 rs2624825 chr3:50154989 G/A cg21467203 chr3:49911342 NA 0.44 7.82 0.39 6.74e-14 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.501 rs162381 chr21:44920915 A/G cg04455712 chr21:45112962 RRP1B -0.45 -7.13 -0.36 5.92e-12 Mean corpuscular volume; LIHC cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg19318889 chr4:1322082 MAEA 0.49 8.4 0.41 1.22e-15 Obesity-related traits; LIHC cis rs7847628 0.550 rs12343516 chr9:123603469 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.94 18.13 0.7 5.96e-52 Birth weight; LIHC cis rs7614311 0.639 rs111234932 chr3:63842449 C/T cg22134162 chr3:63841271 THOC7 -0.56 -6.38 -0.33 5.62e-10 Lung function (FVC);Lung function (FEV1); LIHC trans rs561341 0.800 rs7209766 chr17:30234848 T/A cg20587970 chr11:113659929 NA -0.56 -7.15 -0.36 5.39e-12 Hip circumference adjusted for BMI; LIHC cis rs10744422 1.000 rs4759355 chr12:123316566 A/G cg25930673 chr12:123319894 HIP1R -0.89 -11.68 -0.53 9.76e-27 Schizophrenia; LIHC cis rs951366 0.617 rs823074 chr1:205774839 T/C cg14159672 chr1:205819179 PM20D1 0.86 12.22 0.55 9.54e-29 Menarche (age at onset); LIHC cis rs172166 0.694 rs1225716 chr6:28113746 A/C cg16479474 chr6:28041457 NA 0.38 6.44 0.33 4.05e-10 Cardiac Troponin-T levels; LIHC cis rs317689 0.918 rs610192 chr12:69739941 T/C cg14784868 chr12:69753453 YEATS4 0.68 10.24 0.48 1.22e-21 Response to diuretic therapy; LIHC cis rs10751667 0.600 rs10902264 chr11:1003523 G/A ch.11.42038R chr11:967971 AP2A2 0.6 11.19 0.52 5.7e-25 Alzheimer's disease (late onset); LIHC cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg05665937 chr4:1216051 CTBP1 0.46 6.07 0.31 3.48e-9 Obesity-related traits; LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs68092024 0.731 rs792841 chr3:99471308 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.44 6.11 0.31 2.64e-9 Cleft lip with or without cleft palate; LIHC cis rs910316 0.810 rs77939209 chr14:75670070 A/G cg08847533 chr14:75593920 NEK9 -0.8 -15.59 -0.64 8.9e-42 Height; LIHC cis rs7238033 0.624 rs11877086 chr18:43307338 C/A cg20610511 chr18:43302872 SLC14A1 0.4 6.66 0.34 1.1e-10 Bladder cancer; LIHC cis rs10744422 1.000 rs7294991 chr12:123286780 C/T cg22842854 chr12:123319900 HIP1R -0.63 -7.64 -0.38 2.28e-13 Schizophrenia; LIHC cis rs473651 0.503 rs515342 chr2:239367296 A/G cg18131467 chr2:239335373 ASB1 -0.72 -10.01 -0.48 7.49e-21 Multiple system atrophy; LIHC cis rs3617 0.591 rs11918800 chr3:52868145 G/A cg11645453 chr3:52864694 ITIH4 -0.22 -5.95 -0.31 6.65e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs7927592 0.871 rs11228284 chr11:68322767 A/T cg20283391 chr11:68216788 NA -0.52 -7.85 -0.39 5.44e-14 Total body bone mineral density; LIHC cis rs1008375 1.000 rs7697889 chr4:17617961 G/T cg02297831 chr4:17616191 MED28 0.48 7.38 0.37 1.24e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6424115 0.965 rs2502986 chr1:24135292 G/T cg15997130 chr1:24165203 NA 0.47 9.76 0.47 5.2e-20 Immature fraction of reticulocytes; LIHC cis rs9640161 0.789 rs2098053 chr7:150043205 G/A cg10018233 chr7:150070692 REPIN1 0.55 8.45 0.42 8.32e-16 Blood protein levels;Circulating chemerin levels; LIHC cis rs11628318 0.853 rs10151896 chr14:103039936 G/C cg23461800 chr14:103021989 NA -0.5 -7.12 -0.36 6.6e-12 Platelet count; LIHC cis rs10256972 0.685 rs10263665 chr7:1110628 A/G cg07308232 chr7:1071921 C7orf50 -0.48 -7.63 -0.38 2.28e-13 Longevity;Endometriosis; LIHC cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg13607699 chr17:42295918 UBTF 0.45 7.17 0.36 4.6e-12 Total body bone mineral density; LIHC cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg22528358 chr1:107598549 PRMT6 0.68 10.94 0.51 4.47e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2710642 0.721 rs1872790 chr2:62890222 T/C cg17519650 chr2:63277830 OTX1 0.5 7.15 0.36 5.22e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs2108225 0.934 rs2301989 chr7:107443871 G/A cg18560240 chr7:107437656 SLC26A3 -0.49 -7.61 -0.38 2.76e-13 Ulcerative colitis; LIHC trans rs61931739 0.500 rs11053261 chr12:34530810 C/T cg26384229 chr12:38710491 ALG10B 0.78 9.55 0.46 2.64e-19 Morning vs. evening chronotype; LIHC cis rs2832191 0.720 rs4643617 chr21:30485278 T/C cg24692254 chr21:30365293 RNF160 -0.68 -12.4 -0.56 1.97e-29 Dental caries; LIHC cis rs875971 0.723 rs28391294 chr7:65654315 T/C cg11764359 chr7:65958608 NA -0.84 -14.15 -0.61 4.2500000000000003e-36 Aortic root size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T ch.8.2087691R chr8:103313232 UBR5 -0.34 -6.08 -0.31 3.22e-9 Cognitive function; LIHC cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg02931644 chr1:25747376 RHCE 0.37 8.4 0.41 1.19e-15 Erythrocyte sedimentation rate; LIHC cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg10360323 chr17:41437877 NA 0.4 5.95 0.31 6.78e-9 Menopause (age at onset); LIHC cis rs67460515 0.892 rs13059340 chr3:161062631 T/C cg17135325 chr3:160939158 NMD3 0.53 7.56 0.38 3.64e-13 Parkinson's disease; LIHC cis rs12477438 0.798 rs4851179 chr2:99568774 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.1 -16.3 -0.66 1.31e-44 Chronic sinus infection; LIHC cis rs10751667 0.600 rs11246377 chr11:999796 G/T cg10932868 chr11:921992 NA 0.35 6.52 0.33 2.46e-10 Alzheimer's disease (late onset); LIHC cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg27297192 chr10:134578999 INPP5A 0.54 7.99 0.4 2.12e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2576037 0.583 rs2187091 chr18:44520048 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.72 11.45 0.53 6.74e-26 Personality dimensions; LIHC cis rs1707322 0.721 rs11211158 chr1:46132850 C/G cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC trans rs3780486 0.801 rs6476398 chr9:33119241 C/T cg20290983 chr6:43655470 MRPS18A 1.18 28.67 0.84 5.47e-93 IgG glycosylation; LIHC cis rs34779708 0.931 rs59418206 chr10:35331624 G/A cg03585969 chr10:35415529 CREM 0.86 12.85 0.57 4.19e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7546 0.501 rs12102426 chr16:4922450 T/G cg08329684 chr16:4932620 PPL 0.38 6.67 0.34 1.01e-10 Cancer; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg13568946 chr8:12516530 NA 0.5 6.1 0.31 2.94e-9 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs1707322 0.752 rs12047629 chr1:46162802 G/A cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs2727020 0.634 rs11040331 chr11:49345726 T/C cg03929089 chr4:120376271 NA -0.65 -9.07 -0.44 9.39e-18 Coronary artery disease; LIHC cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg12311346 chr5:56204834 C5orf35 -0.58 -7.56 -0.38 3.81e-13 Initial pursuit acceleration; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg26338869 chr17:61819248 STRADA 0.54 7.19 0.36 4.19e-12 Height; LIHC cis rs2933343 0.951 rs7648327 chr3:128570708 A/G cg25356066 chr3:128598488 ACAD9 0.54 7.17 0.36 4.64e-12 IgG glycosylation; LIHC cis rs943466 1.000 rs747692 chr6:33737436 C/T cg25922239 chr6:33757077 LEMD2 -0.5 -6.12 -0.31 2.58e-9 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.54 -6.48 -0.33 3.25e-10 Renal cell carcinoma; LIHC cis rs74417235 0.517 rs13179034 chr5:154059487 C/A cg25588787 chr5:154027256 NA 0.38 5.73 0.3 2.17e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs7044106 0.791 rs10818473 chr9:123484155 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.72 11.62 0.53 1.57e-26 Hip circumference adjusted for BMI; LIHC cis rs240764 0.853 rs1875400 chr6:101020968 T/C cg09795085 chr6:101329169 ASCC3 -0.49 -6.61 -0.34 1.49e-10 Neuroticism; LIHC cis rs244293 0.730 rs9303362 chr17:53062553 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.47 -7.04 -0.36 1.04e-11 Menarche (age at onset); LIHC cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg18252515 chr7:66147081 NA -1.3 -16.9 -0.67 5.23e-47 Diabetic kidney disease; LIHC cis rs751728 1.000 rs6920075 chr6:33731797 C/T cg25922239 chr6:33757077 LEMD2 0.46 7.43 0.37 8.83e-13 Crohn's disease; LIHC cis rs7412746 0.658 rs4970987 chr1:150949682 T/C cg15448220 chr1:150897856 SETDB1 0.44 6.79 0.34 4.95e-11 Melanoma; LIHC trans rs9929218 0.906 rs4783565 chr16:68750190 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.22 -0.45 3.03e-18 Colorectal cancer; LIHC cis rs7248779 1.000 rs7248779 chr19:2403564 G/T cg22729335 chr19:2427816 TIMM13 -0.61 -9.34 -0.45 1.31e-18 Cortisol levels (saliva); LIHC cis rs6942756 1.000 rs1473236 chr7:128880831 G/T cg02491457 chr7:128862824 NA -0.72 -11.39 -0.52 1.09e-25 White matter hyperintensity burden; LIHC cis rs7264396 0.747 rs2425112 chr20:34319775 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.63 -0.53 1.46e-26 Total cholesterol levels; LIHC cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg25894440 chr7:65020034 NA -0.56 -6.49 -0.33 3.01e-10 Diabetic kidney disease; LIHC cis rs1005277 0.579 rs1740745 chr10:38520056 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs7829975 0.871 rs777709 chr8:8583872 T/C cg06636001 chr8:8085503 FLJ10661 -0.46 -7.34 -0.37 1.57e-12 Mood instability; LIHC cis rs2228479 0.850 rs11640188 chr16:89807732 C/T cg00800038 chr16:89945340 TCF25 -0.61 -8.94 -0.44 2.52e-17 Skin colour saturation; LIHC cis rs10832963 1.000 rs10832962 chr11:18656271 C/T cg20219074 chr11:18656078 SPTY2D1 0.83 13.74 0.6 1.7e-34 Breast cancer; LIHC cis rs79149102 0.579 rs7342591 chr15:75306863 C/T cg15902774 chr15:75289873 SCAMP5 -0.4 -6.07 -0.31 3.43e-9 Lung cancer; LIHC cis rs1215050 0.791 rs2123099 chr4:98803456 A/G cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.86e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9534288 0.830 rs940 chr13:46627480 C/G cg15192986 chr13:46630673 CPB2 -0.56 -8.57 -0.42 3.67e-16 Blood protein levels; LIHC cis rs35110281 0.667 rs7282405 chr21:45123611 C/G cg04455712 chr21:45112962 RRP1B 0.51 8.93 0.44 2.58e-17 Mean corpuscular volume; LIHC cis rs9993613 0.967 rs10213071 chr4:73436348 C/G cg15102770 chr4:73434591 ADAMTS3 -0.39 -6.07 -0.31 3.38e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs2073300 0.793 rs75758241 chr20:23434696 A/G cg12062639 chr20:23401060 NAPB 0.78 9.47 0.46 4.77e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs67257959 0.708 rs10405158 chr19:17195997 A/G cg16202187 chr19:17186497 HAUS8;MYO9B 0.36 5.8 0.3 1.5e-8 Selective IgA deficiency; LIHC cis rs7100689 0.646 rs1340380 chr10:82115619 T/C cg01528321 chr10:82214614 TSPAN14 0.77 10.08 0.48 4.45e-21 Post bronchodilator FEV1; LIHC cis rs916888 0.821 rs199507 chr17:44858855 A/G cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2286885 0.965 rs10987301 chr9:129250688 T/C cg15282417 chr9:129245246 FAM125B -0.39 -6.28 -0.32 1.03e-9 Intraocular pressure; LIHC cis rs35110281 0.776 rs1073522 chr21:45009219 T/A cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.32e-23 Mean corpuscular volume; LIHC cis rs7945705 0.967 rs1569408 chr11:8909732 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.41 6.96 0.35 1.7e-11 Hemoglobin concentration; LIHC trans rs2797160 1.000 rs2747719 chr6:126009214 C/T cg05039488 chr6:79577232 IRAK1BP1 0.46 6.5 0.33 2.88e-10 Endometrial cancer; LIHC cis rs7249142 0.597 rs7250650 chr19:19285989 A/T cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.93 -0.35 2.11e-11 IgG glycosylation; LIHC cis rs3736594 0.649 rs867282 chr2:27951658 A/G cg27432699 chr2:27873401 GPN1 -0.43 -6.73 -0.34 7.14e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs4700695 0.841 rs152995 chr5:65323172 G/A cg21114390 chr5:65439923 SFRS12 0.45 5.73 0.3 2.26e-8 Facial morphology (factor 19); LIHC cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg10295955 chr4:187884368 NA -0.96 -22.55 -0.77 1.2e-69 Lobe attachment (rater-scored or self-reported); LIHC trans rs13113518 0.812 rs2412648 chr4:56321067 T/G cg15358633 chr12:38710606 ALG10B 0.44 6.29 0.32 9.77e-10 Height; LIHC cis rs7572733 0.515 rs1401096 chr2:198823828 A/G cg03934865 chr2:198174659 NA 0.47 6.75 0.34 6.45e-11 Dermatomyositis; LIHC cis rs10791097 0.694 rs2155749 chr11:130751094 G/T cg22079354 chr11:130786696 SNX19 0.43 6.19 0.32 1.73e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2243480 1.000 rs34192067 chr7:65887657 C/A cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs4474465 0.646 rs10793334 chr11:78278792 C/T cg27205649 chr11:78285834 NARS2 -0.51 -8.21 -0.41 4.63e-15 Alzheimer's disease (survival time); LIHC cis rs7208859 0.623 rs9914499 chr17:29107588 G/A cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs34172651 0.517 rs36113933 chr16:24838862 A/G cg00339695 chr16:24857497 SLC5A11 0.74 10.86 0.51 8.57e-24 Intelligence (multi-trait analysis); LIHC cis rs4474465 0.646 rs4945301 chr11:78283362 A/G cg27205649 chr11:78285834 NARS2 0.5 7.82 0.39 6.79e-14 Alzheimer's disease (survival time); LIHC cis rs8103278 0.740 rs72626215 chr19:46294136 G/A cg02376097 chr19:46275166 DMPK -0.42 -6.13 -0.31 2.48e-9 Coronary artery disease; LIHC cis rs9381040 1.000 rs9381040 chr6:41154650 C/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -6.03 -0.31 4.31e-9 Alzheimer's disease (late onset); LIHC cis rs875971 0.660 rs3857686 chr7:66036191 C/T cg11764359 chr7:65958608 NA -0.72 -10.98 -0.51 3.13e-24 Aortic root size; LIHC cis rs7106204 1.000 rs7931691 chr11:24221123 C/A ch.11.24196551F chr11:24239977 NA 0.69 6.96 0.35 1.75e-11 Response to Homoharringtonine (cytotoxicity); LIHC cis rs6952808 0.595 rs2398705 chr7:2164995 G/A cg02951883 chr7:2050386 MAD1L1 -0.65 -10.64 -0.5 4.99e-23 Bipolar disorder and schizophrenia; LIHC cis rs4665809 1.000 rs4665309 chr2:26335502 T/C cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs1577917 0.916 rs7759727 chr6:86518878 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.72 -0.3 2.34e-8 Response to antipsychotic treatment; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09250607 chr7:1529409 INTS1 0.38 6.23 0.32 1.38e-9 Longevity; LIHC cis rs2933343 0.700 rs2630257 chr3:128644015 T/C cg24203234 chr3:128598194 ACAD9 0.46 6.47 0.33 3.43e-10 IgG glycosylation; LIHC cis rs2067615 0.579 rs10861655 chr12:107129419 A/G cg15890332 chr12:107067104 RFX4 -0.27 -6.46 -0.33 3.63e-10 Heart rate; LIHC cis rs7188697 0.885 rs246194 chr16:58573901 G/A cg02549819 chr16:58548995 SETD6 -0.45 -7.18 -0.36 4.43e-12 QT interval; LIHC cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg13047869 chr3:10149882 C3orf24 0.53 6.7 0.34 8.73e-11 Alzheimer's disease; LIHC cis rs12701220 0.725 rs13242971 chr7:1055515 C/T cg26769984 chr7:1090371 C7orf50 0.59 7.43 0.37 8.86e-13 Bronchopulmonary dysplasia; LIHC trans rs3780486 1.000 rs3780486 chr9:33139453 C/T cg20290983 chr6:43655470 MRPS18A 1.08 20.36 0.74 6.32e-61 IgG glycosylation; LIHC trans rs10506458 0.915 rs998505 chr12:63400018 C/T cg22491629 chr6:157744540 C6orf35 -0.61 -10.93 -0.51 4.6e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs1215050 0.740 rs700739 chr4:99022546 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -6.31 -0.32 8.74e-10 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs916888 0.773 rs199534 chr17:44824213 T/G cg13957321 chr17:43675089 NA 0.5 7.91 0.39 3.59e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6089584 0.830 rs4925331 chr20:60580174 T/C cg23262073 chr20:60523788 NA -0.28 -5.73 -0.3 2.16e-8 Body mass index; LIHC cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.08 0.31 3.13e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2180341 0.814 rs6914131 chr6:127737489 T/C cg27446573 chr6:127587934 RNF146 0.8 13.32 0.58 6.62e-33 Breast cancer; LIHC cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg21782813 chr7:2030301 MAD1L1 0.52 9.25 0.45 2.54e-18 Bipolar disorder and schizophrenia; LIHC cis rs477692 0.905 rs693402 chr10:131422882 G/A cg05714579 chr10:131428358 MGMT 0.49 8.38 0.41 1.37e-15 Response to temozolomide; LIHC cis rs4474465 0.607 rs7930161 chr11:78268878 C/A cg27205649 chr11:78285834 NARS2 0.41 6.11 0.31 2.77e-9 Alzheimer's disease (survival time); LIHC cis rs10197940 0.578 rs2432956 chr2:152287831 C/T cg19508488 chr2:152266495 RIF1 -0.53 -6.46 -0.33 3.65e-10 Lung cancer; LIHC cis rs1799949 0.827 rs74252763 chr17:41402020 C/T cg05368731 chr17:41323189 NBR1 0.72 11.81 0.54 3.14e-27 Menopause (age at onset); LIHC cis rs2204008 0.683 rs7305703 chr12:38138381 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.59 0.5 7.72e-23 Bladder cancer; LIHC cis rs722599 0.715 rs12147629 chr14:75307588 A/G cg11812906 chr14:75593930 NEK9 -0.43 -6.54 -0.33 2.18e-10 IgG glycosylation; LIHC cis rs7223966 1.000 rs9899788 chr17:61756384 G/A cg05941027 chr17:61774174 LIMD2 0.3 5.97 0.31 5.91e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7131987 0.622 rs7294598 chr12:29531989 A/C cg00204748 chr12:29376779 FAR2 -0.4 -7.43 -0.37 8.74e-13 QT interval; LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg07157834 chr1:205819609 PM20D1 0.67 10.19 0.48 1.86e-21 Menarche (age at onset); LIHC cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg04944784 chr2:26401820 FAM59B -0.71 -9.17 -0.44 4.43e-18 Gut microbiome composition (summer); LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg18306943 chr3:40428807 ENTPD3 -0.4 -6.81 -0.35 4.35e-11 Renal cell carcinoma; LIHC cis rs2832191 0.791 rs2832181 chr21:30481371 G/T cg24692254 chr21:30365293 RNF160 -0.7 -12.72 -0.57 1.25e-30 Dental caries; LIHC cis rs9818758 0.607 rs34580506 chr3:49113713 C/A cg06212747 chr3:49208901 KLHDC8B -0.69 -5.91 -0.3 8.11e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg02951883 chr7:2050386 MAD1L1 -0.55 -8.16 -0.4 6.61e-15 Bipolar disorder and schizophrenia; LIHC cis rs9457247 0.663 rs2282861 chr6:167440128 C/T cg23791538 chr6:167370224 RNASET2 -0.61 -10.55 -0.5 1.05e-22 Crohn's disease; LIHC cis rs651907 0.557 rs34457525 chr3:101435225 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.5 -0.33 2.85e-10 Colorectal cancer; LIHC cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg22800045 chr5:56110881 MAP3K1 0.67 8.62 0.42 2.57e-16 Initial pursuit acceleration; LIHC cis rs4665809 1.000 rs4665809 chr2:26251361 C/T cg04944784 chr2:26401820 FAM59B 0.69 8.63 0.42 2.3e-16 Gut microbiome composition (summer); LIHC cis rs12701220 0.901 rs12701710 chr7:1090396 A/G cg26769984 chr7:1090371 C7orf50 -0.58 -7.56 -0.38 3.63e-13 Bronchopulmonary dysplasia; LIHC cis rs7607369 0.782 rs514799 chr2:219411203 A/G cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs11644362 1.000 rs11644362 chr16:12994097 T/C cg06890432 chr16:12997467 SHISA9 -0.39 -6.62 -0.34 1.4e-10 Positive affect;Subjective well-being; LIHC trans rs2096176 0.606 rs7899567 chr10:26343197 A/G cg01396774 chr2:218299024 DIRC3 0.31 6.05 0.31 3.89e-9 Obesity-related traits; LIHC cis rs4453791 0.872 rs35479964 chr3:38912926 C/T cg02254461 chr3:39195904 CSRNP1 0.66 5.89 0.3 9.44e-9 Social communication problems; LIHC cis rs41271473 0.526 rs2182202 chr1:228733959 G/C cg10167378 chr1:228756711 NA 0.65 6.53 0.33 2.35e-10 Chronic lymphocytic leukemia; LIHC cis rs17685 0.712 rs28456330 chr7:75810542 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.36 -5.93 -0.31 7.26e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10242455 0.557 rs2404487 chr7:99038057 G/A cg18809830 chr7:99032528 PTCD1 -0.82 -6.37 -0.33 5.95e-10 Blood metabolite levels; LIHC cis rs8060686 0.641 rs79375669 chr16:68099262 A/T cg05110241 chr16:68378359 PRMT7 -0.6 -6.95 -0.35 1.89e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg23131131 chr22:24373011 LOC391322 -0.5 -6.76 -0.34 5.92e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs992157 0.710 rs10169718 chr2:219103580 C/T cg20019365 chr2:219134978 PNKD;AAMP -0.8 -13.48 -0.59 1.61e-33 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20609493 chr15:60420227 NA 0.43 6.23 0.32 1.36e-9 Pancreatic cancer; LIHC cis rs12594515 1.000 rs6493172 chr15:45987213 T/G cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.7e-12 Waist circumference;Weight; LIHC cis rs6502050 0.871 rs6502055 chr17:80070868 G/T cg11859384 chr17:80120422 CCDC57 0.44 5.98 0.31 5.72e-9 Life satisfaction; LIHC cis rs9457247 0.935 rs2757046 chr6:167374353 C/T cg23791538 chr6:167370224 RNASET2 0.69 11.77 0.54 4.42e-27 Crohn's disease; LIHC cis rs7772486 0.875 rs10457793 chr6:146415403 A/G cg05347473 chr6:146136440 FBXO30 0.38 5.95 0.31 6.67e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs35110281 0.715 rs8129601 chr21:45119104 A/G cg21573476 chr21:45109991 RRP1B -0.51 -9.87 -0.47 2.2e-20 Mean corpuscular volume; LIHC cis rs9420 0.925 rs488769 chr11:57450720 A/C cg19752551 chr11:57585705 CTNND1 -0.52 -7.37 -0.37 1.33e-12 Schizophrenia; LIHC cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -14.04 -0.6 1.15e-35 Alzheimer's disease; LIHC cis rs2153535 0.541 rs9405386 chr6:8458067 C/G cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs10197940 0.753 rs2290368 chr2:152266473 T/C cg06191203 chr2:152266755 RIF1 -0.52 -10.0 -0.48 7.85e-21 Lung cancer; LIHC cis rs35883536 0.565 rs2809813 chr1:101032003 A/C cg14515779 chr1:101123966 NA -0.41 -5.81 -0.3 1.43e-8 Monocyte count; LIHC cis rs11763147 1 rs11763147 chr7:65326821 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.32 -5.8 -0.3 1.49e-8 Corneal structure; LIHC cis rs6942756 1.000 rs6467233 chr7:128868656 C/T cg02491457 chr7:128862824 NA -0.71 -11.27 -0.52 2.84e-25 White matter hyperintensity burden; LIHC cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg12311346 chr5:56204834 C5orf35 -0.51 -6.61 -0.34 1.49e-10 Initial pursuit acceleration; LIHC trans rs1814175 0.618 rs7483546 chr11:49714784 C/A cg15704280 chr7:45808275 SEPT13 -0.97 -20.38 -0.74 5.06e-61 Height; LIHC cis rs7264396 0.690 rs2425183 chr20:34450621 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -11.01 -0.51 2.46e-24 Total cholesterol levels; LIHC trans rs1814175 0.645 rs28839231 chr11:50044292 G/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs1728785 1.000 rs1170426 chr16:68603798 C/T cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs5769707 0.681 rs8137111 chr22:50043750 G/A cg01652190 chr22:50026171 C22orf34 -0.35 -7.83 -0.39 6.27e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs10256972 0.758 rs9801444 chr7:1080444 A/C cg22907277 chr7:1156413 C7orf50 -0.42 -5.75 -0.3 1.99e-8 Longevity;Endometriosis; LIHC cis rs11098499 1.000 rs12506395 chr4:120185094 C/T cg09307838 chr4:120376055 NA 0.74 10.87 0.51 7.96e-24 Corneal astigmatism; LIHC cis rs311392 0.526 rs311385 chr8:55101380 T/A cg11783602 chr8:55087084 NA -0.31 -6.23 -0.32 1.37e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs12474201 0.928 rs12999586 chr2:46938736 C/T cg06386533 chr2:46925753 SOCS5 0.74 8.25 0.41 3.5e-15 Height; LIHC cis rs55665837 0.540 rs12788030 chr11:14764684 C/T cg19336497 chr11:14380999 RRAS2 -0.34 -5.74 -0.3 2.13e-8 Vitamin D levels; LIHC cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg00684032 chr4:1343700 KIAA1530 0.52 7.54 0.38 4.36e-13 Obesity-related traits; LIHC cis rs7312774 0.748 rs4964191 chr12:107306497 G/A cg16260113 chr12:107380972 MTERFD3 0.77 10.08 0.48 4.37e-21 Severe influenza A (H1N1) infection; LIHC cis rs3806843 0.868 rs2563281 chr5:140131219 T/A cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs12893668 0.572 rs34000399 chr14:104101417 T/C cg08213375 chr14:104286397 PPP1R13B 0.36 5.87 0.3 1.01e-8 Reticulocyte count; LIHC cis rs77861329 1.000 rs352151 chr3:52210272 C/G cg08692210 chr3:52188851 WDR51A 0.83 7.99 0.4 2.03e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs875971 1.000 rs6957199 chr7:65978519 T/C cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.47e-9 Aortic root size; LIHC cis rs17685 0.712 rs1639620 chr7:75704090 A/G cg04610667 chr7:75704037 NA -0.34 -6.02 -0.31 4.4e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs208520 1.000 rs12193164 chr6:66978962 C/T cg07460842 chr6:66804631 NA 0.67 7.3 0.37 2.1e-12 Exhaled nitric oxide output; LIHC cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg15691649 chr6:25882328 NA -0.65 -8.48 -0.42 7e-16 Intelligence (multi-trait analysis); LIHC cis rs950776 0.518 rs55690619 chr15:78833612 A/G cg06917634 chr15:78832804 PSMA4 -0.93 -14.24 -0.61 1.91e-36 Sudden cardiac arrest; LIHC cis rs2836950 0.545 rs4818001 chr21:40575088 T/C cg17971929 chr21:40555470 PSMG1 -0.4 -6.02 -0.31 4.52e-9 Menarche (age at onset); LIHC cis rs1018836 0.892 rs11776824 chr8:91553256 T/C cg16814680 chr8:91681699 NA -0.58 -9.41 -0.45 7.68e-19 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2481665 0.772 rs6668600 chr1:62536683 C/G cg18591186 chr1:62594603 INADL 0.35 5.94 0.31 7.09e-9 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9733 0.650 rs12125672 chr1:150554470 A/T cg17724175 chr1:150552817 MCL1 -0.37 -7.57 -0.38 3.53e-13 Tonsillectomy; LIHC cis rs12744310 0.887 rs34539673 chr1:41796817 G/A cg03962019 chr1:41807865 NA 0.4 6.35 0.32 6.77e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs8062405 0.755 rs4788078 chr16:28559981 G/A cg07451762 chr16:28383216 NA 0.39 7.05 0.36 9.95e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs798554 0.757 rs1182177 chr7:2874540 C/T cg19346786 chr7:2764209 NA -0.46 -6.59 -0.34 1.69e-10 Height; LIHC cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg11301795 chr4:187892539 NA -0.26 -6.88 -0.35 2.9100000000000002e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7267979 1.000 rs4815404 chr20:25301845 T/G cg24626310 chr20:25276739 ABHD12;PYGB -0.46 -6.77 -0.34 5.65e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs459571 0.959 rs392134 chr9:136909008 G/A cg13789015 chr9:136890014 NCRNA00094 0.45 8.14 0.4 7.33e-15 Platelet distribution width; LIHC cis rs13064411 0.696 rs9836396 chr3:113184282 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.28 -0.32 1.03e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs4665809 1.000 rs2384322 chr2:26291146 C/G cg04944784 chr2:26401820 FAM59B -0.71 -8.94 -0.44 2.43e-17 Gut microbiome composition (summer); LIHC trans rs11098499 0.820 rs2389885 chr4:120533931 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.52 0.46 3.25e-19 Corneal astigmatism; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg11494091 chr17:61959527 GH2 0.45 8.17 0.4 6.04e-15 Prudent dietary pattern; LIHC cis rs1003719 0.715 rs7280251 chr21:38567911 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.24 -0.48 1.21e-21 Eye color traits; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04699474 chr19:9945708 PIN1 -0.53 -6.76 -0.34 5.9e-11 Systolic blood pressure; LIHC cis rs7131987 0.845 rs7299861 chr12:29409667 G/A cg12903224 chr12:29470962 FAR2 -0.37 -5.91 -0.3 8.31e-9 QT interval; LIHC cis rs3824867 0.920 rs3740684 chr11:47468820 C/T cg20307385 chr11:47447363 PSMC3 0.57 7.71 0.38 1.4e-13 Mean corpuscular hemoglobin; LIHC cis rs9300255 0.596 rs11057207 chr12:123730891 T/G cg05973401 chr12:123451056 ABCB9 0.43 5.94 0.31 7.13e-9 Neutrophil percentage of white cells; LIHC cis rs6690583 0.623 rs12041012 chr1:85515644 G/A cg22153463 chr1:85462885 MCOLN2 0.53 6.28 0.32 1.03e-9 Serum sulfate level; LIHC cis rs8108269 1.000 rs10409882 chr19:46160935 C/T cg13320842 chr19:46175254 GIPR 0.43 8.04 0.4 1.48e-14 Type 2 diabetes; LIHC cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs7617773 0.780 rs11130164 chr3:48369034 G/A cg11946769 chr3:48343235 NME6 0.92 11.83 0.54 2.63e-27 Coronary artery disease; LIHC cis rs55823223 0.564 rs12103594 chr17:73855279 C/T cg19302996 chr17:73780495 UNK -0.52 -6.11 -0.31 2.66e-9 Psoriasis; LIHC cis rs826838 0.684 rs12367400 chr12:38618673 G/T cg13010199 chr12:38710504 ALG10B 0.59 6.99 0.35 1.44e-11 Heart rate; LIHC cis rs679087 1.000 rs302315 chr12:29919054 G/C cg14258853 chr12:29935411 TMTC1 -0.5 -7.88 -0.39 4.34e-14 Schizophrenia; LIHC cis rs2070488 0.861 rs2067082 chr3:38438182 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.87 14.97 0.63 2.56e-39 Electrocardiographic conduction measures; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.98 21.57 0.76 9.11e-66 Prudent dietary pattern; LIHC cis rs9811920 0.570 rs1021102 chr3:99603780 T/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -6.89 -0.35 2.64e-11 Axial length; LIHC cis rs62458065 0.640 rs28587905 chr7:32533054 C/T cg20159608 chr7:32802032 NA -0.5 -5.85 -0.3 1.15e-8 Metabolite levels (HVA/MHPG ratio); LIHC cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.76 0.47 5.3e-20 Platelet count; LIHC cis rs986417 1.000 rs1072328 chr14:60876439 C/G cg27398547 chr14:60952738 C14orf39 -0.74 -8.61 -0.42 2.67e-16 Gut microbiota (bacterial taxa); LIHC cis rs739401 0.572 rs404629 chr11:3077025 A/G cg25174290 chr11:3078921 CARS 0.66 10.15 0.48 2.39e-21 Longevity; LIHC cis rs12711979 0.509 rs10195488 chr2:3824135 T/C cg17052675 chr2:3827356 NA -0.7 -15.47 -0.64 2.8e-41 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs11122272 0.668 rs1122131 chr1:231476501 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.34 -0.49 5.63e-22 Hemoglobin concentration; LIHC cis rs1957429 0.808 rs763346 chr14:65330386 A/G cg23373153 chr14:65346875 NA -0.78 -11.18 -0.52 6.07e-25 Pediatric areal bone mineral density (radius); LIHC cis rs7618501 0.521 rs3796386 chr3:49899795 G/A cg05623727 chr3:50126028 RBM5 0.36 5.97 0.31 5.83e-9 Intelligence (multi-trait analysis); LIHC cis rs4653767 0.573 rs708770 chr1:226912135 C/T cg05262829 chr1:226921576 ITPKB 0.38 7.57 0.38 3.48e-13 Parkinson's disease; LIHC cis rs7408868 1.000 rs7249525 chr19:15277309 G/A cg14696996 chr19:15285081 NOTCH3 0.54 7.09 0.36 7.55e-12 Pulse pressure; LIHC cis rs4141404 0.851 rs8135417 chr22:31559255 G/A cg07713946 chr22:31675144 LIMK2 -0.29 -6.26 -0.32 1.13e-9 Paclitaxel-induced neuropathy; LIHC cis rs782590 0.837 rs2627769 chr2:55927288 G/C cg03859395 chr2:55845619 SMEK2 0.88 14.72 0.62 2.42e-38 Metabolic syndrome; LIHC cis rs7909074 0.832 rs10793564 chr10:45386352 C/A cg04218760 chr10:45406644 TMEM72 -0.24 -7.47 -0.37 6.54e-13 Mean corpuscular volume; LIHC trans rs2243480 0.522 rs73150635 chr7:65972490 C/T cg10756647 chr7:56101905 PSPH 1.07 11.54 0.53 3.16e-26 Diabetic kidney disease; LIHC cis rs644799 0.648 rs1255178 chr11:95471908 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.61 10.35 0.49 4.94e-22 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs61550741 0.655 rs68194389 chr21:32500745 T/G cg23515853 chr17:79372528 BAHCC1 -0.57 -6.09 -0.31 3.08e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs2115630 1.000 rs2879828 chr15:85361977 G/T cg12501888 chr15:85177176 SCAND2 -0.49 -7.45 -0.37 7.75e-13 P wave terminal force; LIHC cis rs7903847 0.642 rs11189180 chr10:99143529 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1670533 0.872 rs935969 chr4:1062588 A/G cg27284194 chr4:1044797 NA 0.59 8.84 0.43 5.15e-17 Recombination rate (females); LIHC cis rs2479724 0.901 rs10947987 chr6:41754370 C/T cg17623882 chr6:41773611 USP49 0.56 8.43 0.41 9.49e-16 Menarche (age at onset); LIHC cis rs11112613 0.775 rs7299470 chr12:105961773 G/A cg03607813 chr12:105948248 NA 0.61 11.74 0.54 5.73e-27 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs6545883 0.965 rs6718887 chr2:61727215 G/A cg14146966 chr2:61757674 XPO1 0.49 8.62 0.42 2.6e-16 Tuberculosis; LIHC cis rs6840360 0.615 rs55932132 chr4:152463897 G/T cg22705602 chr4:152727874 NA -0.32 -6.34 -0.32 7.15e-10 Intelligence (multi-trait analysis); LIHC cis rs2933343 0.729 rs1680785 chr3:128644816 C/T cg25356066 chr3:128598488 ACAD9 0.52 7.21 0.36 3.68e-12 IgG glycosylation; LIHC cis rs919433 1.000 rs6741380 chr2:198165121 A/G cg10820045 chr2:198174542 NA 0.6 10.35 0.49 5.02e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg12463550 chr7:65579703 CRCP 0.69 7.13 0.36 6.01e-12 Diabetic kidney disease; LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.21 -0.32 1.5e-9 Menopause (age at onset); LIHC cis rs4319547 0.695 rs6488939 chr12:122858250 T/C cg23029597 chr12:123009494 RSRC2 -0.5 -7.22 -0.36 3.35e-12 Body mass index; LIHC cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg22963979 chr7:1858916 MAD1L1 -0.39 -6.2 -0.32 1.6e-9 Bipolar disorder and schizophrenia; LIHC cis rs1865760 0.566 rs1971509 chr6:26085777 T/C cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs9916302 0.904 rs1619021 chr17:37739274 G/A cg00129232 chr17:37814104 STARD3 -0.44 -6.88 -0.35 2.87e-11 Glomerular filtration rate (creatinine); LIHC cis rs17060993 0.618 rs17056484 chr8:26848328 C/T cg24127101 chr8:26149548 PPP2R2A 0.77 6.76 0.34 5.94e-11 Musician's dystonia; LIHC cis rs6545883 0.965 rs1562308 chr2:61768421 A/C cg15711740 chr2:61764176 XPO1 -0.43 -6.05 -0.31 3.9e-9 Tuberculosis; LIHC cis rs12497850 0.931 rs6414613 chr3:49035885 C/T cg07636037 chr3:49044803 WDR6 0.93 16.41 0.66 4.98e-45 Parkinson's disease; LIHC cis rs240764 0.658 rs7746961 chr6:101215244 A/G cg09795085 chr6:101329169 ASCC3 -0.41 -5.73 -0.3 2.19e-8 Neuroticism; LIHC cis rs7937890 1.000 rs7937890 chr11:14396485 C/T cg19336497 chr11:14380999 RRAS2 -0.36 -6.35 -0.32 6.96e-10 Mitochondrial DNA levels; LIHC cis rs1707322 0.686 rs2275085 chr1:46085852 C/T cg03146154 chr1:46216737 IPP -0.57 -9.85 -0.47 2.68e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9640161 0.711 rs3800781 chr7:150027324 T/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.55 -9.26 -0.45 2.34e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs7959452 0.535 rs7135092 chr12:69658330 T/C cg22834771 chr12:69754056 YEATS4 -0.47 -7.94 -0.39 2.97e-14 Blood protein levels; LIHC cis rs4665809 1.000 rs2384322 chr2:26291146 C/G cg27170947 chr2:26402098 FAM59B -0.69 -8.55 -0.42 4.31e-16 Gut microbiome composition (summer); LIHC cis rs986417 1.000 rs1268621 chr14:60921571 G/A cg27398547 chr14:60952738 C14orf39 -0.81 -9.56 -0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs6674176 0.628 rs3791116 chr1:44414156 T/A cg12908607 chr1:44402522 ARTN -0.47 -8.06 -0.4 1.33e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6424115 0.737 rs10917430 chr1:24170458 C/T cg15997130 chr1:24165203 NA -0.39 -7.01 -0.35 1.28e-11 Immature fraction of reticulocytes; LIHC cis rs6088580 0.524 rs2378251 chr20:33276750 C/T cg08999081 chr20:33150536 PIGU -0.41 -7.06 -0.36 9.19e-12 Glomerular filtration rate (creatinine); LIHC cis rs4819052 0.655 rs2330102 chr21:46690968 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 10.24 0.48 1.25e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs16854884 0.657 rs1025984 chr3:143756187 C/G cg06585982 chr3:143692056 C3orf58 -0.55 -7.26 -0.37 2.64e-12 Economic and political preferences (feminism/equality); LIHC cis rs6500602 0.727 rs8051389 chr16:4570570 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.76 0.3 1.92e-8 Schizophrenia; LIHC cis rs7520050 0.966 rs4076006 chr1:46438076 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 6.03 0.31 4.24e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7772486 0.790 rs2265469 chr6:146219049 T/C cg23711669 chr6:146136114 FBXO30 0.63 11.05 0.51 1.77e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs6424115 0.931 rs2982390 chr1:24147830 G/C cg10978503 chr1:24200527 CNR2 0.38 9.01 0.44 1.46e-17 Immature fraction of reticulocytes; LIHC cis rs992157 0.710 rs6719789 chr2:219057810 G/T cg00012203 chr2:219082015 ARPC2 -0.88 -15.27 -0.64 1.6e-40 Colorectal cancer; LIHC cis rs225245 0.817 rs1049379 chr17:33998802 G/C cg05299278 chr17:33885742 SLFN14 0.24 6.44 0.33 4.09e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs763121 0.853 rs5757213 chr22:39053888 C/T cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg18306943 chr3:40428807 ENTPD3 0.43 7.53 0.38 4.63e-13 Renal cell carcinoma; LIHC cis rs6502050 0.835 rs35070385 chr17:80128447 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs950776 0.518 rs12915428 chr15:78823368 G/A cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg26451873 chr13:26829095 CDK8 -0.42 -6.19 -0.32 1.68e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg11905131 chr22:24372483 LOC391322 -0.75 -11.11 -0.51 1.08e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2404618 0.587 rs6994849 chr8:1492839 G/T cg13402656 chr8:1511478 DLGAP2 0.57 12.21 0.55 1.09e-28 Lung cancer; LIHC cis rs67311347 0.911 rs6776044 chr3:40377503 T/G cg24209194 chr3:40518798 ZNF619 0.46 6.56 0.33 1.95e-10 Renal cell carcinoma; LIHC cis rs918629 0.530 rs3777201 chr5:95234630 G/T cg10483112 chr5:95245456 ELL2 -0.36 -6.55 -0.33 2.07e-10 IgG glycosylation; LIHC cis rs67478160 0.619 rs10083367 chr14:104314183 C/G cg08213375 chr14:104286397 PPP1R13B -0.65 -12.49 -0.56 9.64e-30 Schizophrenia; LIHC cis rs7552404 1.000 rs4949879 chr1:76237143 G/A cg03433033 chr1:76189801 ACADM 0.68 9.31 0.45 1.57e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs77633900 0.614 rs280012 chr15:76974854 G/T cg21673338 chr15:77095150 SCAPER -0.49 -7.52 -0.38 4.89e-13 Non-glioblastoma glioma;Glioma; LIHC cis rs9303280 0.806 rs10852936 chr17:38031714 C/T cg11212589 chr17:38028394 ZPBP2 0.34 6.85 0.35 3.35e-11 Self-reported allergy; LIHC cis rs9733 0.596 rs12063547 chr1:150674053 G/T cg13175981 chr1:150552382 MCL1 0.44 6.2 0.32 1.63e-9 Tonsillectomy; LIHC cis rs7613875 0.543 rs34034116 chr3:49959156 C/A cg21467203 chr3:49911342 NA -0.57 -10.42 -0.49 2.82e-22 Body mass index; LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs6089584 0.830 rs4925331 chr20:60580174 T/C cg13770153 chr20:60521292 NA -0.33 -6.42 -0.33 4.47e-10 Body mass index; LIHC cis rs758324 0.891 rs652839 chr5:131281106 G/C cg06307176 chr5:131281290 NA -0.42 -6.1 -0.31 2.81e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs6424115 1.000 rs4649115 chr1:24155731 A/G cg10978503 chr1:24200527 CNR2 -0.38 -9.05 -0.44 1.14e-17 Immature fraction of reticulocytes; LIHC cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.45 7.33 0.37 1.72e-12 Bipolar disorder; LIHC cis rs7178375 1.000 rs10163148 chr15:31212684 C/G cg19680485 chr15:31195859 MTMR15 -0.56 -6.12 -0.31 2.62e-9 Hypertriglyceridemia; LIHC cis rs7089973 0.628 rs11196953 chr10:116607707 A/G cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14913181 chr1:6845123 CAMTA1 0.47 6.18 0.32 1.87e-9 Lung function (FEV1/FVC); LIHC cis rs1707322 0.752 rs11211173 chr1:46219376 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7927592 0.913 rs7109294 chr11:68332093 A/G cg20283391 chr11:68216788 NA -0.52 -7.72 -0.39 1.28e-13 Total body bone mineral density; LIHC cis rs6545883 0.929 rs3732170 chr2:61749716 C/T cg14146966 chr2:61757674 XPO1 0.47 8.24 0.41 3.77e-15 Tuberculosis; LIHC cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg04944784 chr2:26401820 FAM59B 0.66 7.09 0.36 7.87e-12 Gut microbiome composition (summer); LIHC cis rs1005277 0.505 rs200937 chr10:38135772 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.5 -0.46 3.75e-19 Extrinsic epigenetic age acceleration; LIHC cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg24004478 chr7:855632 UNC84A -0.48 -7.94 -0.39 2.96e-14 Perceived unattractiveness to mosquitoes; LIHC cis rs9549367 0.664 rs9549689 chr13:113848387 G/A cg00898013 chr13:113819073 PROZ -0.47 -7.78 -0.39 8.51e-14 Platelet distribution width; LIHC cis rs7666738 0.515 rs13118898 chr4:98792893 T/A cg05340658 chr4:99064831 C4orf37 0.51 6.7 0.34 8.84e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs9393777 0.623 rs9358944 chr6:26469875 A/C cg12826209 chr6:26865740 GUSBL1 0.65 6.86 0.35 3.17e-11 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.522 rs289643 chr10:37941494 T/G cg23533926 chr12:111358616 MYL2 -0.33 -6.61 -0.34 1.5e-10 Extrinsic epigenetic age acceleration; LIHC cis rs875971 1.000 rs4718307 chr7:65610988 A/G cg18876405 chr7:65276391 NA -0.39 -6.89 -0.35 2.67e-11 Aortic root size; LIHC cis rs929354 0.772 rs1002389 chr7:156968323 C/G cg05182265 chr7:156933206 UBE3C -0.31 -5.86 -0.3 1.07e-8 Body mass index; LIHC cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg06634786 chr22:41940651 POLR3H 0.73 7.59 0.38 3.16e-13 Vitiligo; LIHC cis rs796364 0.906 rs281789 chr2:200780698 T/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.7 8.33 0.41 1.99e-15 Schizophrenia; LIHC cis rs4925386 0.959 rs6121989 chr20:60916713 A/T cg06026331 chr20:60912101 LAMA5 -0.51 -8.54 -0.42 4.58e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs7614311 0.731 rs3774719 chr3:63950338 C/A cg22134162 chr3:63841271 THOC7 -0.55 -6.08 -0.31 3.28e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs7086627 0.515 rs12245180 chr10:82211897 C/G cg01528321 chr10:82214614 TSPAN14 0.54 7.65 0.38 2.07e-13 Post bronchodilator FEV1; LIHC cis rs10193935 0.901 rs2374405 chr2:42479874 A/C cg27598129 chr2:42591480 NA -0.7 -10.27 -0.49 9.67e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg01420254 chr6:26195488 NA 0.51 5.77 0.3 1.77e-8 Gout;Renal underexcretion gout; LIHC cis rs10857712 0.904 rs36118799 chr10:135222369 T/G cg01444801 chr10:135216882 MTG1 -0.66 -9.88 -0.47 2.12e-20 Systemic lupus erythematosus; LIHC cis rs1707322 1.000 rs9429186 chr1:46539687 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.68 -0.34 9.69e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11122272 0.735 rs2355873 chr1:231477442 A/G cg06096015 chr1:231504339 EGLN1 0.5 9.18 0.44 4.18e-18 Hemoglobin concentration; LIHC cis rs7258465 1.000 rs8107367 chr19:18564705 A/G cg10790698 chr19:18539756 SSBP4 -0.37 -7.75 -0.39 1.04e-13 Breast cancer; LIHC cis rs1691799 0.899 rs1168314 chr12:66746937 A/G cg16791601 chr12:66731901 HELB -0.56 -13.94 -0.6 2.85e-35 White blood cell count (basophil); LIHC cis rs10493773 0.748 rs12758511 chr1:86165987 C/T cg17807903 chr1:86174739 ZNHIT6 -0.56 -10.23 -0.48 1.37e-21 Urate levels in overweight individuals; LIHC cis rs7412746 0.634 rs7521592 chr1:150821691 A/C cg15448220 chr1:150897856 SETDB1 0.39 5.85 0.3 1.13e-8 Melanoma; LIHC cis rs2153535 0.580 rs7741403 chr6:8530578 C/T cg07606381 chr6:8435919 SLC35B3 -0.78 -11.56 -0.53 2.5e-26 Motion sickness; LIHC cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg07424592 chr7:64974309 NA -0.79 -9.28 -0.45 1.95e-18 Diabetic kidney disease; LIHC cis rs1712517 0.836 rs7093039 chr10:105149547 A/G cg05636881 chr10:105038444 INA 0.45 6.97 0.35 1.63e-11 Migraine; LIHC cis rs10744422 1.000 rs2292135 chr12:123334075 G/A cg07706471 chr12:123319906 HIP1R -0.62 -8.23 -0.41 3.94e-15 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07090025 chr1:1510437 SSU72 -0.5 -6.26 -0.32 1.17e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06154860 chr7:14029085 ETV1 0.48 6.74 0.34 6.8e-11 Pancreatic cancer; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg02290350 chr8:58132656 NA 0.49 11.68 0.53 9.48e-27 Developmental language disorder (linguistic errors); LIHC cis rs7618501 1.000 rs6785549 chr3:49736565 G/A cg24110177 chr3:50126178 RBM5 0.42 6.62 0.34 1.39e-10 Intelligence (multi-trait analysis); LIHC cis rs9324022 0.584 rs72698722 chr14:101181881 C/T cg18089426 chr14:101175970 NA 0.49 6.75 0.34 6.5e-11 Plateletcrit; LIHC cis rs1552244 0.744 rs6763366 chr3:10033544 T/C cg08888203 chr3:10149979 C3orf24 0.45 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs8113308 0.752 rs73068868 chr19:52491001 A/G cg25782003 chr19:52490127 ZNF350 0.63 5.73 0.3 2.16e-8 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg04944784 chr2:26401820 FAM59B 0.71 9.07 0.44 9.7e-18 Gut microbiome composition (summer); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25577648 chr10:73137008 NA 0.46 6.46 0.33 3.55e-10 Lung function (FEV1/FVC); LIHC cis rs611744 0.608 rs667742 chr8:109254003 T/C cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs7927592 0.913 rs4316515 chr11:68308840 A/T cg16797656 chr11:68205561 LRP5 -0.52 -8.22 -0.41 4.17e-15 Total body bone mineral density; LIHC cis rs3020736 0.500 rs5996110 chr22:42493767 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs735396 0.595 rs2258287 chr12:121454313 G/T cg15155738 chr12:121454335 C12orf43 0.57 8.16 0.4 6.44e-15 N-glycan levels; LIHC cis rs2290416 0.892 rs61652493 chr8:144669164 G/A cg26536354 chr8:144654954 C8orf73 0.55 6.2 0.32 1.67e-9 Attention deficit hyperactivity disorder; LIHC cis rs10423674 0.526 rs2023878 chr19:18834124 A/G cg16673477 chr19:18812017 CRTC1 0.45 7.26 0.37 2.68e-12 Menarche (age at onset); LIHC cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.660 rs10229345 chr7:65982168 G/C cg11764359 chr7:65958608 NA 0.66 9.12 0.44 6.44e-18 Aortic root size; LIHC trans rs6598955 0.617 rs11247895 chr1:26599542 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs1866706 0.896 rs7119811 chr11:12882376 T/G cg25843174 chr11:12811716 TEAD1 0.28 5.94 0.31 6.92e-9 Intelligence (multi-trait analysis); LIHC cis rs875971 1.000 rs6460295 chr7:65882728 T/C cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs9611565 0.921 rs2235846 chr22:41741042 G/C cg03806693 chr22:41940476 POLR3H -0.46 -6.04 -0.31 3.91e-9 Vitiligo; LIHC cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg27170947 chr2:26402098 FAM59B 0.67 8.41 0.41 1.12e-15 Gut microbiome composition (summer); LIHC cis rs3820068 0.581 rs72645893 chr1:15930943 C/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs7091068 0.662 rs829106 chr10:95441742 G/T cg20715218 chr10:95462985 C10orf4 0.61 6.57 0.33 1.86e-10 Urinary tract infection frequency; LIHC cis rs12477438 0.765 rs62154861 chr2:99590235 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.73 -10.89 -0.51 6.82e-24 Chronic sinus infection; LIHC cis rs6089584 0.962 rs6142913 chr20:60566950 A/G cg12751644 chr20:60527061 NA -0.35 -5.85 -0.3 1.16e-8 Body mass index; LIHC cis rs6762477 0.748 rs11717349 chr3:50223977 C/T cg24110177 chr3:50126178 RBM5 0.38 5.83 0.3 1.28e-8 Menarche (age at onset); LIHC cis rs3008870 0.920 rs975452 chr1:67480190 A/T cg02640540 chr1:67518911 SLC35D1 0.44 6.01 0.31 4.67e-9 Lymphocyte percentage of white cells; LIHC cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg20090690 chr10:134436459 INPP5A 0.43 6.08 0.31 3.21e-9 Migraine; LIHC cis rs2303759 0.918 rs9749416 chr19:49885005 G/A cg24324837 chr19:49891574 CCDC155 0.38 5.94 0.31 6.97e-9 Multiple sclerosis; LIHC cis rs2439831 1.000 rs689781 chr15:43792097 T/C cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.34e-9 Lung cancer in ever smokers; LIHC cis rs35883536 0.588 rs955338 chr1:101108794 G/C cg14515779 chr1:101123966 NA -0.59 -11.17 -0.52 6.6e-25 Monocyte count; LIHC cis rs2637030 0.559 rs1490768 chr5:53018495 C/G cg06476337 chr5:52856530 NDUFS4 0.41 6.72 0.34 7.67e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs2197308 0.703 rs10880251 chr12:37903297 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.12e-23 Morning vs. evening chronotype; LIHC cis rs2933343 0.553 rs35979399 chr3:128697313 G/A cg25356066 chr3:128598488 ACAD9 0.46 6.21 0.32 1.53e-9 IgG glycosylation; LIHC cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg08645402 chr16:4508243 NA 0.38 7.3 0.37 2.08e-12 Schizophrenia; LIHC cis rs11190604 1.000 rs10786598 chr10:102291579 G/A cg07080220 chr10:102295463 HIF1AN 0.57 8.09 0.4 1.05e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2404602 0.647 rs2404604 chr15:76991105 A/G cg03037974 chr15:76606532 NA -0.58 -9.66 -0.46 1.1e-19 Blood metabolite levels; LIHC cis rs13191362 1.000 rs55822577 chr6:163069710 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.77 6.74 0.34 6.68e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1697139 0.935 rs1625369 chr5:66513022 C/T cg16691251 chr5:66510806 NA 0.51 7.37 0.37 1.3e-12 Breast cancer; LIHC cis rs7408868 0.908 rs10418660 chr19:15278635 A/G cg14696996 chr19:15285081 NOTCH3 0.54 7.08 0.36 8.26e-12 Pulse pressure; LIHC cis rs73001065 0.591 rs11668386 chr19:19531910 A/G cg03709012 chr19:19516395 GATAD2A 0.9 9.66 0.46 1.13e-19 LDL cholesterol; LIHC cis rs5417 0.775 rs222852 chr17:7140606 A/G cg25256661 chr17:7137939 DVL2 0.46 7.23 0.36 3.09e-12 Diastolic blood pressure; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg26338869 chr17:61819248 STRADA 0.59 8.7 0.43 1.42e-16 Prudent dietary pattern; LIHC cis rs66887589 0.616 rs11098497 chr4:120187068 C/T cg09307838 chr4:120376055 NA 0.54 8.01 0.4 1.86e-14 Diastolic blood pressure; LIHC cis rs1664789 1.000 rs1694056 chr5:53276913 A/T ch.5.1024479R chr5:53302184 ARL15 0.48 7.68 0.38 1.65e-13 Waist circumference adjusted for body mass index; LIHC cis rs7212590 0.881 rs7214032 chr17:57885828 T/C cg10252138 chr17:58120427 NA -0.6 -6.03 -0.31 4.16e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs907683 0.533 rs12469789 chr2:220293242 C/T cg15015639 chr2:220282977 DES 0.35 8.44 0.42 9.17e-16 Resting heart rate; LIHC cis rs9858213 1 rs9858213 chr3:49731861 G/T cg02487422 chr3:49467188 NICN1 -0.44 -5.74 -0.3 2.09e-8 Educational attainment; LIHC cis rs34779708 0.733 rs12249814 chr10:35542757 T/C cg03585969 chr10:35415529 CREM 0.76 10.96 0.51 3.65e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs5769765 0.773 rs4075331 chr22:50302850 A/G cg02269571 chr22:50332266 NA -0.62 -8.76 -0.43 9.12e-17 Schizophrenia; LIHC cis rs1348850 0.668 rs12618542 chr2:178494520 A/G cg27490568 chr2:178487706 NA 0.71 9.14 0.44 5.66e-18 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9733 0.596 rs56058687 chr1:150635066 C/T cg15448220 chr1:150897856 SETDB1 0.39 6.15 0.32 2.2e-9 Tonsillectomy; LIHC cis rs2153535 0.580 rs2152347 chr6:8474281 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02545393 chr11:70244902 CTTN 0.47 6.44 0.33 3.98e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.954 rs7654587 chr4:120388406 C/T cg09307838 chr4:120376055 NA 0.77 12.05 0.55 4.03e-28 Corneal astigmatism; LIHC cis rs2370759 1.000 rs11597888 chr10:32635834 G/A cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs9543976 1.000 rs7989568 chr13:76155564 T/C cg01531495 chr13:76123901 UCHL3 0.49 5.89 0.3 9.46e-9 Diabetic retinopathy; LIHC cis rs6964587 1.000 rs28584017 chr7:91719168 G/A cg17063962 chr7:91808500 NA 1.01 19.29 0.72 1.22e-56 Breast cancer; LIHC cis rs4638749 0.677 rs2219081 chr2:108844350 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -5.96 -0.31 6.23e-9 Blood pressure; LIHC cis rs2455799 0.613 rs6795100 chr3:15793798 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs3768617 0.811 rs10911233 chr1:183052585 G/A ch.1.3577855R chr1:183094577 LAMC1 0.48 7.69 0.38 1.62e-13 Fuchs's corneal dystrophy; LIHC cis rs7572733 0.534 rs1518365 chr2:198809410 T/C cg10820045 chr2:198174542 NA 0.48 7.36 0.37 1.39e-12 Dermatomyositis; LIHC cis rs11585357 0.895 rs72633806 chr1:17617943 A/G cg08277548 chr1:17600880 PADI3 -0.64 -6.79 -0.34 4.83e-11 Hair shape; LIHC cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg21951975 chr1:209979733 IRF6 0.44 7.16 0.36 5e-12 Cleft lip with or without cleft palate; LIHC cis rs896854 0.738 rs509594 chr8:95967156 C/G cg16049864 chr8:95962084 TP53INP1 0.59 9.77 0.47 4.76e-20 Type 2 diabetes; LIHC cis rs4853012 0.838 rs4563249 chr2:74354016 G/T cg19729930 chr2:74357872 NA 0.84 19.57 0.73 9.8e-58 Gestational age at birth (maternal effect); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg23667555 chr12:25403962 KRAS -0.44 -6.57 -0.33 1.83e-10 Bilirubin levels; LIHC cis rs1707322 1.000 rs785478 chr1:46491635 C/T cg03146154 chr1:46216737 IPP -0.48 -7.81 -0.39 7.3e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg02034447 chr16:89574710 SPG7 0.49 7.51 0.38 5.23e-13 Multiple myeloma (IgH translocation); LIHC cis rs10751667 0.961 rs6597954 chr11:987677 G/A cg06064525 chr11:970664 AP2A2 -0.49 -12.17 -0.55 1.42e-28 Alzheimer's disease (late onset); LIHC cis rs4148883 0.737 rs13148577 chr4:100060836 G/A cg12011299 chr4:100065546 ADH4 0.36 7.19 0.36 4.09e-12 Alcohol dependence; LIHC cis rs9326248 0.954 rs4938349 chr11:117021923 C/T cg10130564 chr11:117069849 TAGLN 0.34 5.84 0.3 1.24e-8 Blood protein levels; LIHC cis rs6429082 0.764 rs291369 chr1:235691913 T/C cg26050004 chr1:235667680 B3GALNT2 0.46 7.17 0.36 4.63e-12 Adiposity; LIHC trans rs9951602 0.512 rs7241419 chr18:76640778 C/G cg02800362 chr5:177631904 HNRNPAB 0.65 10.32 0.49 6.58e-22 Obesity-related traits; LIHC cis rs6840360 1.000 rs6535818 chr4:152650882 T/G cg22705602 chr4:152727874 NA -0.35 -7.37 -0.37 1.31e-12 Intelligence (multi-trait analysis); LIHC cis rs12594515 1.000 rs6493170 chr15:45987019 G/A cg01629716 chr15:45996671 NA 0.52 9.64 0.46 1.26e-19 Waist circumference;Weight; LIHC cis rs7312933 0.670 rs10880269 chr12:42606135 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.7 0.38 1.47e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs67311347 0.506 rs55962832 chr3:40244451 T/C cg00656387 chr3:40428638 ENTPD3 0.43 6.7 0.34 8.4e-11 Renal cell carcinoma; LIHC cis rs950169 0.649 rs12901010 chr15:84699034 G/A cg17507749 chr15:85114479 UBE2QP1 0.74 6.78 0.34 5.26e-11 Schizophrenia; LIHC cis rs6750047 1.000 rs6750047 chr2:38276549 A/G cg07380506 chr2:38303506 CYP1B1 0.53 6.56 0.33 2.04e-10 Cutaneous malignant melanoma;Melanoma; LIHC cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs11690935 0.851 rs6731562 chr2:172798262 T/C cg13550731 chr2:172543902 DYNC1I2 -0.44 -7.41 -0.37 1.01e-12 Schizophrenia; LIHC cis rs6840360 0.638 rs2406974 chr4:152601841 G/A cg22705602 chr4:152727874 NA -0.35 -7.36 -0.37 1.37e-12 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.872 rs13046834 chr21:47701485 T/C cg12016809 chr21:47604291 C21orf56 0.41 5.97 0.31 6.06e-9 Testicular germ cell tumor; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg22734451 chr15:78219748 LOC645752 -0.46 -6.84 -0.35 3.56e-11 Calcium levels; LIHC cis rs2153535 0.580 rs6421948 chr6:8531020 T/C cg23788917 chr6:8435910 SLC35B3 0.63 8.93 0.44 2.58e-17 Motion sickness; LIHC cis rs798554 1.000 rs798550 chr7:2760609 A/G cg19346786 chr7:2764209 NA -0.46 -6.86 -0.35 3.23e-11 Height; LIHC cis rs2153535 0.601 rs1855768 chr6:8472969 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC trans rs1973993 0.967 rs11165643 chr1:96924097 C/T cg10631902 chr5:14652156 NA 0.35 8.41 0.41 1.15e-15 Weight; LIHC cis rs7474896 1.000 rs11011344 chr10:38004846 C/T cg25427524 chr10:38739819 LOC399744 -0.48 -6.08 -0.31 3.28e-9 Obesity (extreme); LIHC cis rs921968 0.643 rs1055816 chr2:219501328 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.17 0.32 1.97e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7089973 0.604 rs11196952 chr10:116607592 G/A cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg04944784 chr2:26401820 FAM59B 0.72 9.32 0.45 1.45e-18 Gut microbiome composition (summer); LIHC cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg04727924 chr7:799746 HEATR2 -0.4 -6.0 -0.31 5.09e-9 Perceived unattractiveness to mosquitoes; LIHC cis rs4819052 0.851 rs1006779 chr21:46670752 A/G cg22633049 chr21:46681294 NA -0.34 -5.99 -0.31 5.19e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04389950 chr6:106720478 ATG5 -0.32 -6.07 -0.31 3.48e-9 Pancreatic cancer; LIHC cis rs11702148 0.552 rs2300374 chr21:34885590 A/T cg14850771 chr21:34775459 IFNGR2 0.47 7.66 0.38 1.97e-13 Mean corpuscular hemoglobin; LIHC cis rs6684514 1.000 rs10908495 chr1:156263940 T/C cg16558208 chr1:156270281 VHLL 0.53 10.05 0.48 5.28e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC trans rs4650994 0.525 rs4650997 chr1:178530744 T/A cg05059571 chr16:84539110 KIAA1609 -0.46 -7.56 -0.38 3.79e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg08219700 chr8:58056026 NA 0.45 5.73 0.3 2.25e-8 Developmental language disorder (linguistic errors); LIHC cis rs9457247 1.000 rs10946198 chr6:167404432 C/T cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC cis rs198426 0.506 rs198462 chr11:61524119 G/A cg27386326 chr11:61587980 NA -0.33 -5.94 -0.31 6.83e-9 Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid); LIHC cis rs3749237 0.595 rs4855877 chr3:49448527 T/C cg03060546 chr3:49711283 APEH 0.58 9.56 0.46 2.34e-19 Resting heart rate; LIHC cis rs6089584 0.893 rs2281735 chr20:60582540 T/A cg06108461 chr20:60628389 TAF4 -0.93 -14.9 -0.63 4.83e-39 Body mass index; LIHC cis rs637571 0.522 rs542332 chr11:65744421 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.4 6.04 0.31 3.94e-9 Eosinophil percentage of white cells; LIHC cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs2576037 0.583 rs616900 chr18:44410849 T/A cg19077165 chr18:44547161 KATNAL2 -0.45 -6.84 -0.35 3.56e-11 Personality dimensions; LIHC cis rs12079745 0.590 rs10919151 chr1:169334096 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.81 -7.12 -0.36 6.37e-12 QT interval; LIHC cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.2e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs826838 1.000 rs4768328 chr12:39129315 C/T cg26384229 chr12:38710491 ALG10B -0.61 -8.99 -0.44 1.7e-17 Heart rate; LIHC cis rs72843506 0.656 rs2385960 chr17:19938217 C/A cg12065943 chr17:19881925 AKAP10 -0.41 -6.93 -0.35 2.14e-11 Schizophrenia; LIHC cis rs782590 0.574 rs12991445 chr2:55675939 C/T cg03859395 chr2:55845619 SMEK2 0.46 7.03 0.36 1.1e-11 Metabolic syndrome; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.15 0.55 1.79e-28 Prudent dietary pattern; LIHC cis rs7618501 0.633 rs6771546 chr3:49968572 T/C cg21467203 chr3:49911342 NA -0.45 -8.11 -0.4 9.32e-15 Intelligence (multi-trait analysis); LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg16145915 chr7:1198662 ZFAND2A -0.42 -11.52 -0.53 3.72e-26 Longevity;Endometriosis; LIHC cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg04267008 chr7:1944627 MAD1L1 0.62 9.56 0.46 2.42e-19 Bipolar disorder and schizophrenia; LIHC trans rs1005277 0.579 rs1740732 chr10:38491385 C/T cg17830980 chr10:43048298 ZNF37B -0.5 -9.65 -0.46 1.17e-19 Extrinsic epigenetic age acceleration; LIHC cis rs4650994 0.593 rs7540745 chr1:178529757 C/T cg05350800 chr1:178550844 NA -0.32 -7.11 -0.36 6.93e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs782590 0.935 rs2627776 chr2:55873301 T/A cg18811423 chr2:55921094 PNPT1 0.98 15.52 0.64 1.75e-41 Metabolic syndrome; LIHC cis rs1506636 0.720 rs633590 chr7:123442156 G/A cg03229431 chr7:123269106 ASB15 0.31 6.01 0.31 4.64e-9 Plateletcrit;Platelet count; LIHC cis rs7520050 0.966 rs785494 chr1:46586626 C/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.8 0.3 1.5e-8 Red blood cell count;Reticulocyte count; LIHC cis rs362296 0.698 rs3129319 chr4:3265381 A/G cg06533319 chr4:3265114 C4orf44 0.34 6.55 0.33 2.13e-10 Parental longevity (mother's age at death); LIHC cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.18 11.83 0.54 2.74e-27 Platelet count; LIHC cis rs9311474 0.607 rs34005367 chr3:52558904 A/T cg18404041 chr3:52824283 ITIH1 -0.47 -7.43 -0.37 8.88e-13 Electroencephalogram traits; LIHC cis rs1023500 0.573 rs133377 chr22:42466950 C/T cg04733989 chr22:42467013 NAGA 0.66 9.59 0.46 1.93e-19 Schizophrenia; LIHC trans rs2243480 1.000 rs2462569 chr7:65474846 C/T cg10756647 chr7:56101905 PSPH -1.07 -13.39 -0.59 3.74e-33 Diabetic kidney disease; LIHC trans rs11098499 0.909 rs17046118 chr4:120387496 T/G cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs9918079 0.560 rs7438356 chr4:15624770 C/T cg04067612 chr4:15429572 C1QTNF7 -0.27 -5.93 -0.31 7.36e-9 Obesity-related traits; LIHC cis rs3758785 0.679 rs11819857 chr11:94228236 T/G cg21580213 chr11:94231278 ANKRD49 -0.36 -5.96 -0.31 6.43e-9 Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy); LIHC cis rs2019960 0.759 rs2648844 chr8:129178530 T/C cg15331705 chr8:129180010 NA -0.37 -6.71 -0.34 7.89e-11 Hodgkin's lymphoma;Multiple sclerosis; LIHC cis rs12477438 0.520 rs13012481 chr2:99754290 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.62 0.62 5.83e-38 Chronic sinus infection; LIHC cis rs7116495 0.609 rs949324 chr11:71714526 G/C cg10381502 chr11:71823885 C11orf51 -1.03 -9.31 -0.45 1.59e-18 Severe influenza A (H1N1) infection; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01087208 chr20:60494922 CDH4 -0.23 -6.74 -0.34 6.87e-11 Calcium levels; LIHC cis rs367615 0.918 rs72797472 chr5:108881343 C/T cg17395555 chr5:108820864 NA 0.35 7.22 0.36 3.3e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg01448562 chr3:133502909 NA -0.42 -6.59 -0.34 1.63e-10 Iron status biomarkers; LIHC cis rs7131987 0.621 rs3782506 chr12:29445422 A/C cg14222432 chr12:29376421 FAR2 -0.36 -6.97 -0.35 1.68e-11 QT interval; LIHC cis rs8058578 1.000 rs7204278 chr16:30730274 A/G cg00531865 chr16:30841666 NA -0.38 -5.9 -0.3 8.51e-9 Multiple myeloma; LIHC cis rs8005677 1.000 rs8005677 chr14:23376678 T/C cg07971674 chr14:23388846 RBM23 -0.41 -5.89 -0.3 9.2e-9 Cognitive ability (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18504358 chr14:23340787 LRP10 0.4 6.44 0.33 3.96e-10 Cognitive function; LIHC cis rs7582720 1.000 rs77230711 chr2:203805552 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7223966 0.655 rs9906882 chr17:61634382 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.16 0.32 2.05e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg16434002 chr17:42200994 HDAC5 -0.54 -7.77 -0.39 9.27e-14 Total body bone mineral density; LIHC cis rs2075371 0.966 rs2544225 chr7:133995838 A/C cg11752832 chr7:134001865 SLC35B4 0.51 7.59 0.38 3.04e-13 Mean platelet volume; LIHC cis rs10276381 0.786 rs73089302 chr7:28187134 G/A cg23620719 chr7:28220237 JAZF1 0.63 7.82 0.39 6.43e-14 Crohn's disease; LIHC cis rs7572733 0.534 rs2574832 chr2:198704818 T/G cg03934865 chr2:198174659 NA 0.46 6.59 0.34 1.69e-10 Dermatomyositis; LIHC trans rs6058796 0.892 rs66897337 chr20:31256593 T/C cg02600331 chr11:130417168 NA 0.36 7.75 0.39 1.03e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs9399135 0.967 rs9399129 chr6:135285148 C/A cg22676075 chr6:135203613 NA 0.39 6.29 0.32 9.78e-10 Red blood cell count; LIHC cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg03264133 chr6:25882463 NA -0.61 -8.68 -0.42 1.68e-16 Blood metabolite levels; LIHC cis rs10791097 0.694 rs1050071 chr11:130747231 C/G cg14779329 chr11:130786720 SNX19 0.4 5.76 0.3 1.84e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs6951245 0.882 rs10256720 chr7:1210825 C/G cg18402987 chr7:1209562 NA 0.86 5.77 0.3 1.74e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2204008 0.660 rs2320745 chr12:38239101 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.96 0.31 6.27e-9 Bladder cancer; LIHC cis rs2242116 0.932 rs4683301 chr3:46931478 A/T cg02527881 chr3:46936655 PTH1R 0.53 11.77 0.54 4.4e-27 Birth weight; LIHC cis rs4908760 0.792 rs10864361 chr1:8726721 C/T cg20416874 chr1:8611966 RERE 0.65 13.34 0.59 5.49e-33 Vitiligo; LIHC cis rs4555082 0.874 rs28822720 chr14:105746282 T/C cg06808227 chr14:105710500 BRF1 -0.64 -8.71 -0.43 1.33e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs9457247 0.935 rs2757050 chr6:167377165 G/T cg23791538 chr6:167370224 RNASET2 0.69 11.76 0.54 4.7e-27 Crohn's disease; LIHC cis rs9814567 0.929 rs1863912 chr3:134205227 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.09 -0.55 2.81e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg18306943 chr3:40428807 ENTPD3 0.34 6.09 0.31 2.96e-9 Renal cell carcinoma; LIHC cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.928 rs6970357 chr7:65968878 T/C cg11764359 chr7:65958608 NA 0.91 16.89 0.67 5.59e-47 Aortic root size; LIHC cis rs2073300 0.609 rs6132606 chr20:23367453 G/A cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs244293 0.965 rs244343 chr17:53197612 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.5 -0.38 5.39e-13 Menarche (age at onset); LIHC cis rs11161851 0.550 rs11162359 chr1:75461044 G/A cg11196437 chr1:75593865 LHX8 0.3 5.72 0.3 2.37e-8 Visceral fat; LIHC cis rs910316 1.000 rs175492 chr14:75545220 A/C cg08847533 chr14:75593920 NEK9 0.88 18.97 0.72 2.53e-55 Height; LIHC cis rs60871478 0.838 rs7789321 chr7:800977 A/G cg05535760 chr7:792225 HEATR2 0.94 12.9 0.57 2.74e-31 Cerebrospinal P-tau181p levels; LIHC cis rs28829049 0.597 rs12745238 chr1:19393710 C/T cg13387374 chr1:19411106 UBR4 0.46 7.36 0.37 1.34e-12 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs8062405 0.755 rs62031607 chr16:28631530 A/T cg07382826 chr16:28625726 SULT1A1 0.46 6.81 0.35 4.42e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21293397 chr19:35454992 ZNF792 0.42 6.09 0.31 3e-9 Pancreatic cancer; LIHC trans rs7668874 0.731 rs9993719 chr4:116748942 T/C cg08917878 chr5:172668965 NA -0.3 -6.05 -0.31 3.89e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs8180040 0.967 rs4858890 chr3:47405456 A/G cg27129171 chr3:47204927 SETD2 -0.65 -10.67 -0.5 4.01e-23 Colorectal cancer; LIHC cis rs903552 1.000 rs4965873 chr15:102004023 A/G cg06707286 chr15:102010195 PCSK6 0.46 6.52 0.33 2.53e-10 Diabetic kidney disease; LIHC cis rs2250402 0.510 rs8031319 chr15:40323692 A/G cg01081584 chr15:40268610 EIF2AK4 -0.56 -6.61 -0.34 1.48e-10 Corneal curvature; LIHC cis rs892961 0.965 rs2411111 chr17:75402540 A/T cg05865280 chr17:75406074 SEPT9 0.56 13.43 0.59 2.53e-33 Airflow obstruction; LIHC trans rs2727020 0.754 rs1851990 chr11:49413336 C/T cg15704280 chr7:45808275 SEPT13 -0.79 -12.55 -0.56 5.8e-30 Coronary artery disease; LIHC cis rs6831352 0.918 rs7670241 chr4:100059619 G/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs9640161 0.659 rs77354576 chr7:150013300 A/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.44 -7.83 -0.39 6.35e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg20607798 chr8:58055168 NA 0.63 8.13 0.4 7.81e-15 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg02782426 chr3:40428986 ENTPD3 0.34 6.36 0.33 6.32e-10 Renal cell carcinoma; LIHC cis rs61774743 0.521 rs60144015 chr1:41845246 C/A cg08462924 chr1:41848221 NA 0.33 5.93 0.31 7.31e-9 Intelligence (multi-trait analysis); LIHC cis rs4478037 0.822 rs9863331 chr3:33123235 G/T cg27203090 chr3:33138513 GLB1;TMPPE -0.52 -6.51 -0.33 2.6e-10 Major depressive disorder; LIHC cis rs332507 0.632 rs3755682 chr3:124356662 A/C cg05980111 chr3:124395277 KALRN 0.3 5.76 0.3 1.88e-8 Plateletcrit; LIHC cis rs760762 0.660 rs6072328 chr20:39913996 T/C cg06424997 chr20:39929561 ZHX3 0.36 5.91 0.3 8.39e-9 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; LIHC cis rs1348850 0.793 rs6734528 chr2:178493731 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.18 0.4 5.58e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs769267 0.895 rs1000237 chr19:19518316 T/A cg15052019 chr19:19431593 KIAA0892;SF4 0.42 5.96 0.31 6.21e-9 Tonsillectomy; LIHC cis rs7246657 0.891 rs7257495 chr19:37823876 C/G cg23950597 chr19:37808831 NA -0.44 -5.94 -0.31 6.86e-9 Coronary artery calcification; LIHC cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg24549020 chr5:56110836 MAP3K1 -0.47 -6.06 -0.31 3.62e-9 Initial pursuit acceleration; LIHC cis rs11583043 0.918 rs58029001 chr1:101393409 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.42 0.41 1.05e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4604732 0.536 rs10925056 chr1:247650472 T/C cg02104434 chr1:247694406 LOC148824;OR2C3 0.26 6.16 0.32 2.01e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs9902453 0.868 rs9896012 chr17:28470091 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 10.01 0.48 7.14e-21 Coffee consumption (cups per day); LIHC cis rs11673344 0.730 rs826314 chr19:37450435 C/T cg27390819 chr19:37464633 NA -0.53 -6.4 -0.33 5.27e-10 Obesity-related traits; LIHC cis rs1355223 0.872 rs7112608 chr11:34699269 G/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.11 -0.31 2.7e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs9790314 0.934 rs455386 chr3:161102495 A/T cg03342759 chr3:160939853 NMD3 -0.73 -8.63 -0.42 2.3e-16 Morning vs. evening chronotype; LIHC cis rs11122272 0.735 rs2250734 chr1:231485958 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.51 0.46 3.42e-19 Hemoglobin concentration; LIHC cis rs4638749 0.651 rs13385677 chr2:108826152 T/C cg06795125 chr2:108905320 SULT1C2 -0.31 -6.05 -0.31 3.82e-9 Blood pressure; LIHC cis rs7005606 0.532 rs6981660 chr8:32298476 A/G cg16623836 chr8:32453385 NRG1 0.4 5.89 0.3 9.13e-9 Hirschsprung disease; LIHC trans rs867371 1.000 rs8037224 chr15:82464530 G/A cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.11 -0.36 6.94e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs96067 0.805 rs7522400 chr1:36613380 A/G cg24686825 chr1:36642396 MAP7D1 -0.52 -7.29 -0.37 2.14e-12 Corneal structure; LIHC cis rs2243480 1.000 rs13235972 chr7:65883605 C/T cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg00166234 chr2:63272303 LOC100132215;EHBP1 0.49 6.41 0.33 4.89e-10 Lung function (FEV1); LIHC cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg11764359 chr7:65958608 NA -0.58 -6.08 -0.31 3.14e-9 Diabetic kidney disease; LIHC cis rs1552244 0.608 rs3732962 chr3:10048951 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs9303401 0.614 rs2333409 chr17:57139134 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.42 0.56 1.79e-29 Cognitive test performance; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs7534824 0.625 rs61780281 chr1:101324152 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 6.31 0.32 8.73e-10 Refractive astigmatism; LIHC cis rs589448 0.867 rs623853 chr12:69753830 G/A cg20891283 chr12:69753455 YEATS4 0.95 22.44 0.77 3.39e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs898097 0.841 rs9896263 chr17:80902741 A/G cg15664640 chr17:80829946 TBCD 0.67 10.81 0.5 1.26e-23 Breast cancer; LIHC cis rs6952808 0.771 rs4719336 chr7:1916397 T/C cg14004847 chr7:1930337 MAD1L1 -0.53 -7.53 -0.38 4.44e-13 Bipolar disorder and schizophrenia; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg06873352 chr17:61820015 STRADA 0.6 9.32 0.45 1.47e-18 Height; LIHC cis rs7927771 0.965 rs12787112 chr11:47687147 A/G cg18512352 chr11:47633146 NA -0.25 -5.77 -0.3 1.82e-8 Subjective well-being; LIHC cis rs9916302 0.904 rs8079303 chr17:37530755 G/C cg07936489 chr17:37558343 FBXL20 0.85 13.77 0.6 1.22e-34 Glomerular filtration rate (creatinine); LIHC cis rs10876993 0.928 rs774890 chr12:58068388 C/T cg15848620 chr12:58087721 OS9 -0.58 -7.97 -0.4 2.44e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs7772486 0.790 rs6570723 chr6:146151230 A/T cg05347473 chr6:146136440 FBXO30 0.35 5.83 0.3 1.3e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9325144 0.600 rs11183505 chr12:38759110 G/T cg26384229 chr12:38710491 ALG10B -0.55 -7.51 -0.38 5.16e-13 Morning vs. evening chronotype; LIHC trans rs116095464 0.558 rs6882584 chr5:223411 A/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs9309711 0.770 rs13409323 chr2:3488184 C/T cg10845886 chr2:3471009 TTC15 -0.56 -10.15 -0.48 2.41e-21 Neurofibrillary tangles; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg27432699 chr2:27873401 GPN1 -0.51 -7.32 -0.37 1.74e-12 Total body bone mineral density; LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg16132339 chr22:24313637 DDTL;DDT -0.64 -11.02 -0.51 2.36e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1144333 0.850 rs1251274 chr1:76288587 T/C cg10523679 chr1:76189770 ACADM -0.46 -6.64 -0.34 1.21e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg07424592 chr7:64974309 NA 0.82 9.33 0.45 1.38e-18 Diabetic kidney disease; LIHC cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10193935 0.901 rs222469 chr2:42640235 T/C cg27598129 chr2:42591480 NA -0.7 -10.8 -0.5 1.41e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs4665809 0.887 rs4665814 chr2:26273687 G/T cg27170947 chr2:26402098 FAM59B -0.63 -7.85 -0.39 5.35e-14 Gut microbiome composition (summer); LIHC cis rs57244997 0.725 rs7754703 chr6:162440488 T/C cg17173639 chr6:162384350 PARK2 -0.52 -6.64 -0.34 1.23e-10 Mosquito bite size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03004097 chr2:239197782 PER2 -0.46 -6.63 -0.34 1.3100000000000001e-10 Cognitive function; LIHC cis rs2075371 0.863 rs12707139 chr7:133954153 A/G cg20476274 chr7:133979776 SLC35B4 0.69 9.33 0.45 1.35e-18 Mean platelet volume; LIHC cis rs9858542 0.953 rs11926781 chr3:49603289 C/T cg02487422 chr3:49467188 NICN1 -0.43 -5.74 -0.3 2.05e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6545883 0.929 rs2252662 chr2:61670731 T/C cg15711740 chr2:61764176 XPO1 -0.43 -6.01 -0.31 4.66e-9 Tuberculosis; LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg06873352 chr17:61820015 STRADA 0.74 13.53 0.59 1.1e-33 Prudent dietary pattern; LIHC cis rs7582180 0.652 rs11678158 chr2:100932297 T/C cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 3.96e-16 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19349861 chr11:133402246 OPCML 0.51 6.81 0.35 4.34e-11 Lung function (FEV1/FVC); LIHC trans rs208520 1.000 rs12190187 chr6:66973207 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 6.93 0.35 2.06e-11 Exhaled nitric oxide output; LIHC cis rs7953249 0.656 rs2243616 chr12:121406370 G/T cg02403541 chr12:121454288 C12orf43 -0.43 -7.45 -0.37 7.48e-13 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs1707322 0.721 rs9793568 chr1:46130373 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg01518246 chr11:63870912 FLRT1;MACROD1 0.47 6.67 0.34 1.01e-10 Mean platelet volume; LIHC cis rs4819052 0.819 rs34818688 chr21:46672416 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.47 0.37 6.73e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10979 0.894 rs6924940 chr6:143906183 C/T cg25407410 chr6:143891975 LOC285740 -0.36 -5.78 -0.3 1.7e-8 Hypospadias; LIHC cis rs79057730 0.599 rs4720893 chr7:804434 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.81 9.21 0.45 3.34e-18 Initial pursuit acceleration; LIHC cis rs6582630 0.502 rs11181475 chr12:38348922 G/A cg26384229 chr12:38710491 ALG10B 0.57 7.91 0.39 3.6e-14 Drug-induced liver injury (flucloxacillin); LIHC cis rs28735056 0.967 rs56328473 chr18:77636101 C/T cg20368463 chr18:77673604 PQLC1 -0.34 -5.93 -0.31 7.36e-9 Schizophrenia; LIHC cis rs7131987 1.000 rs7131987 chr12:29406488 G/T cg14222432 chr12:29376421 FAR2 0.36 6.89 0.35 2.73e-11 QT interval; LIHC cis rs9916302 0.904 rs2061342 chr17:37405657 T/G cg07936489 chr17:37558343 FBXL20 -0.81 -12.95 -0.57 1.7e-31 Glomerular filtration rate (creatinine); LIHC cis rs1580019 0.922 rs34545272 chr7:32460630 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.93 15.17 0.63 4.1e-40 Cognitive ability; LIHC cis rs4144743 1.000 rs4541130 chr17:45321037 G/A cg18085866 chr17:45331354 ITGB3 -0.54 -7.56 -0.38 3.75e-13 Body mass index; LIHC cis rs7124681 0.584 rs10769285 chr11:47709212 C/T cg20307385 chr11:47447363 PSMC3 0.77 11.58 0.53 2.15e-26 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs7072216 0.763 rs10883091 chr10:100167239 C/T cg26618903 chr10:100175079 PYROXD2 -0.38 -6.09 -0.31 2.98e-9 Metabolite levels; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg26338869 chr17:61819248 STRADA 0.53 7.21 0.36 3.73e-12 Height; LIHC cis rs7799006 0.527 rs3779009 chr7:2203692 G/C cg04267008 chr7:1944627 MAD1L1 -0.45 -6.95 -0.35 1.81e-11 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.44 -7.93 -0.39 3.13e-14 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg20607798 chr8:58055168 NA 0.69 8.23 0.41 3.93e-15 Developmental language disorder (linguistic errors); LIHC cis rs666930 0.967 rs637868 chr1:120257110 A/G cg19096424 chr1:120255104 PHGDH 0.59 8.0 0.4 1.9e-14 Breast cancer; LIHC cis rs35110281 0.627 rs1836855 chr21:44965414 C/G cg21573476 chr21:45109991 RRP1B -0.5 -9.25 -0.45 2.44e-18 Mean corpuscular volume; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg26668828 chr6:292823 DUSP22 -0.66 -9.42 -0.45 6.81e-19 Menopause (age at onset); LIHC cis rs12594515 0.967 rs12595138 chr15:45986108 G/C cg06207120 chr15:45996521 NA 0.34 6.64 0.34 1.27e-10 Waist circumference;Weight; LIHC cis rs6964587 0.967 rs34344935 chr7:91835436 G/A cg17063962 chr7:91808500 NA 1.03 19.81 0.73 1.01e-58 Breast cancer; LIHC cis rs600806 0.713 rs10857786 chr1:110010110 C/G cg23091122 chr1:110024289 SYPL2 -0.47 -6.36 -0.33 6.47e-10 Intelligence (multi-trait analysis); LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.66 9.27 0.45 2.21e-18 Lymphocyte counts; LIHC cis rs8103278 1.000 rs1548029 chr19:46309203 A/C cg11657440 chr19:46296263 DMWD -0.53 -8.37 -0.41 1.54e-15 Coronary artery disease; LIHC cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.46 7.44 0.37 8.4e-13 Bipolar disorder; LIHC cis rs3806843 0.735 rs2563306 chr5:140070017 C/T cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.08e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs12908161 0.959 rs11637728 chr15:85203392 A/T cg12863693 chr15:85201151 NMB 0.46 6.52 0.33 2.5e-10 Schizophrenia; LIHC trans rs61931739 0.517 rs11611190 chr12:34015697 G/A cg26384229 chr12:38710491 ALG10B 0.52 7.2 0.36 3.74e-12 Morning vs. evening chronotype; LIHC cis rs2153535 0.580 rs7450817 chr6:8481421 G/A cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs17711722 0.727 rs781151 chr7:65479878 T/C cg18876405 chr7:65276391 NA 0.54 8.85 0.43 4.88e-17 Calcium levels; LIHC cis rs11098499 0.780 rs12504773 chr4:120562149 G/C cg09307838 chr4:120376055 NA 0.72 10.83 0.51 1.05e-23 Corneal astigmatism; LIHC cis rs722599 0.628 rs12896360 chr14:75278181 A/C cg08847533 chr14:75593920 NEK9 0.47 7.26 0.37 2.54e-12 IgG glycosylation; LIHC cis rs727505 0.954 rs2239532 chr7:124405676 A/C cg23710748 chr7:124431027 NA -0.34 -5.91 -0.3 8.37e-9 Lewy body disease; LIHC cis rs6061231 0.571 rs482010 chr20:60927551 A/G cg24112000 chr20:60950667 NA 0.46 7.34 0.37 1.61e-12 Colorectal cancer; LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg13126279 chr21:47581558 C21orf56 0.45 7.3 0.37 1.97e-12 Testicular germ cell tumor; LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.22 0.41 4.4e-15 Height; LIHC cis rs10540 1.000 rs12794284 chr11:477623 C/T cg03576123 chr11:487126 PTDSS2 -1.0 -7.66 -0.38 1.95e-13 Body mass index; LIHC cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg23262073 chr20:60523788 NA -0.29 -6.09 -0.31 3e-9 Body mass index; LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.526 rs6587542 chr1:150907701 G/T cg15448220 chr1:150897856 SETDB1 0.39 6.25 0.32 1.22e-9 Tonsillectomy; LIHC cis rs919433 1.000 rs2889363 chr2:198163699 A/G cg10820045 chr2:198174542 NA -0.61 -10.61 -0.5 6.34e-23 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg27130769 chr7:5417105 TNRC18 0.44 6.71 0.34 7.9e-11 Immature fraction of reticulocytes; LIHC cis rs651907 0.535 rs11716558 chr3:101528481 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs898097 0.585 rs9892342 chr17:80893029 C/T cg15664640 chr17:80829946 TBCD 0.43 7.11 0.36 6.89e-12 Breast cancer; LIHC cis rs9611565 0.512 rs5751153 chr22:42156561 T/C cg03806693 chr22:41940476 POLR3H 0.98 10.29 0.49 7.98e-22 Vitiligo; LIHC cis rs12474201 0.851 rs13012099 chr2:47010742 G/A cg06386533 chr2:46925753 SOCS5 0.6 6.19 0.32 1.77e-9 Height; LIHC cis rs7208859 0.524 rs59923796 chr17:29064919 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9399135 0.967 rs2327578 chr6:135329969 C/T cg24558204 chr6:135376177 HBS1L 0.42 6.92 0.35 2.24e-11 Red blood cell count; LIHC cis rs6952808 0.782 rs4236271 chr7:1881369 C/T cg21782813 chr7:2030301 MAD1L1 0.41 6.95 0.35 1.91e-11 Bipolar disorder and schizophrenia; LIHC cis rs7909074 1.000 rs10736831 chr10:45402311 G/A cg04218760 chr10:45406644 TMEM72 -0.23 -7.27 -0.37 2.49e-12 Mean corpuscular volume; LIHC cis rs6088590 1.000 rs55753039 chr20:33394940 C/T cg06115741 chr20:33292138 TP53INP2 0.59 8.1 0.4 1.01e-14 Coronary artery disease; LIHC cis rs11971779 0.680 rs11765421 chr7:139025094 G/A cg07862535 chr7:139043722 LUC7L2 0.58 9.92 0.47 1.53e-20 Diisocyanate-induced asthma; LIHC cis rs7904368 0.754 rs12269366 chr10:16850344 G/A cg23933602 chr10:16859644 RSU1 0.61 5.95 0.31 6.75e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg12310025 chr6:25882481 NA -0.64 -9.01 -0.44 1.54e-17 Blood metabolite levels; LIHC cis rs933688 1.000 rs332529 chr5:90789470 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.93 17.76 0.69 1.83e-50 Smoking behavior; LIHC cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.54 -7.8 -0.39 7.33e-14 Lymphocyte counts; LIHC cis rs2629540 0.731 rs11245341 chr10:126408777 G/C cg08799069 chr10:126477246 METTL10 0.48 7.54 0.38 4.31e-13 Cocaine dependence; LIHC cis rs7772486 0.688 rs1884364 chr6:146337817 C/G cg13319975 chr6:146136371 FBXO30 -0.53 -8.36 -0.41 1.61e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs4888262 0.526 rs7205992 chr16:74590578 T/A cg01733217 chr16:74700730 RFWD3 0.79 15.09 0.63 8.58e-40 Testicular germ cell tumor; LIHC cis rs881375 0.933 rs7021206 chr9:123684157 A/G cg14580859 chr9:123691850 NA -0.4 -6.96 -0.35 1.77e-11 Rheumatoid arthritis; LIHC cis rs9473924 0.542 rs9473923 chr6:50833565 A/T cg14470998 chr6:50812995 TFAP2B 0.92 10.56 0.5 9.3e-23 Body mass index; LIHC cis rs1707322 0.721 rs28641748 chr1:46212836 A/G cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs311392 0.554 rs311388 chr8:55101869 T/A cg20636351 chr8:55087400 NA -0.34 -7.09 -0.36 7.97e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs921968 0.573 rs684776 chr2:219324016 T/C cg02985541 chr2:219472218 PLCD4 0.44 7.26 0.37 2.69e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg16434002 chr17:42200994 HDAC5 0.48 7.15 0.36 5.16e-12 Total body bone mineral density; LIHC cis rs6701037 1.000 rs7512413 chr1:175124789 C/T cg17845761 chr1:175162550 KIAA0040 -0.35 -5.74 -0.3 2.11e-8 Alcohol dependence; LIHC cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg26119090 chr2:26468346 HADHA;HADHB 1.16 18.08 0.7 9.53e-52 Gut microbiome composition (summer); LIHC cis rs9291683 0.588 rs35099040 chr4:10018839 T/C cg11266682 chr4:10021025 SLC2A9 0.33 7.14 0.36 5.57e-12 Bone mineral density; LIHC cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg20887711 chr4:1340912 KIAA1530 0.45 6.74 0.34 6.86e-11 Obesity-related traits; LIHC cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.56 8.73 0.43 1.13e-16 Height; LIHC cis rs7700895 0.554 rs154460 chr5:95217430 A/T cg10483112 chr5:95245456 ELL2 0.32 5.74 0.3 2.11e-8 IgG glycosylation; LIHC cis rs7582720 0.943 rs72934546 chr2:203980033 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4713118 0.513 rs202908 chr6:28011551 C/G cg16479474 chr6:28041457 NA 0.39 6.43 0.33 4.42e-10 Parkinson's disease; LIHC trans rs7618501 0.633 rs13060128 chr3:50025028 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.56 9.18 0.44 4.06e-18 Intelligence (multi-trait analysis); LIHC cis rs67311347 0.866 rs3214006 chr3:40352134 C/T cg09455208 chr3:40491958 NA 0.33 6.24 0.32 1.32e-9 Renal cell carcinoma; LIHC trans rs1814175 0.616 rs1851848 chr11:49992254 G/C cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs1577917 0.883 rs9450348 chr6:86598036 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.39 -7.2 -0.36 3.95e-12 Response to antipsychotic treatment; LIHC cis rs9837602 0.529 rs793459 chr3:99520591 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.83 -0.3 1.26e-8 Breast cancer; LIHC cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.38 0.45 9.63e-19 Platelet count; LIHC cis rs9291683 0.588 rs34501273 chr4:9996996 C/T cg11266682 chr4:10021025 SLC2A9 0.29 5.88 0.3 9.69e-9 Bone mineral density; LIHC cis rs595982 0.527 rs17206707 chr19:49361441 A/C cg15549821 chr19:49342101 PLEKHA4 -0.65 -6.47 -0.33 3.39e-10 Red cell distribution width; LIHC cis rs754466 0.580 rs11002293 chr10:79537965 C/T cg17075019 chr10:79541650 NA -0.79 -12.22 -0.55 9.41e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs477895 0.938 rs28395875 chr11:64024048 G/C cg18225595 chr11:63971243 STIP1 0.63 6.38 0.33 5.92e-10 Mean platelet volume; LIHC cis rs6973256 0.569 rs13246174 chr7:133395004 C/T cg03336402 chr7:133662267 EXOC4 -0.37 -5.73 -0.3 2.24e-8 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.566 rs982306 chr6:127777039 T/C cg27446573 chr6:127587934 RNF146 0.75 10.88 0.51 7.33e-24 Breast cancer; LIHC cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg25072359 chr17:41440525 NA 0.37 5.81 0.3 1.45e-8 Menopause (age at onset); LIHC cis rs11190604 1.000 rs10883503 chr10:102275504 C/A cg07080220 chr10:102295463 HIF1AN 0.57 8.07 0.4 1.18e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg05368731 chr17:41323189 NBR1 0.72 12.13 0.55 2.09e-28 Menopause (age at onset); LIHC cis rs12926788 0.689 rs1862450 chr16:24856775 A/G cg00339695 chr16:24857497 SLC5A11 -0.58 -7.99 -0.4 2.06e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs11690935 0.921 rs10200608 chr2:172597929 G/A cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.97 -0.7 2.65e-51 Schizophrenia; LIHC cis rs526821 0.595 rs4938937 chr11:55305507 T/A cg04317927 chr11:55418816 OR4S2 0.48 9.21 0.45 3.29e-18 Pediatric bone mineral density (spine); LIHC cis rs7572733 0.534 rs13026569 chr2:198783330 C/G cg00792783 chr2:198669748 PLCL1 -0.46 -6.79 -0.34 5.11e-11 Dermatomyositis; LIHC cis rs7618501 0.521 rs6774354 chr3:49961780 G/A cg21467203 chr3:49911342 NA -0.58 -10.66 -0.5 4.16e-23 Intelligence (multi-trait analysis); LIHC cis rs651907 0.557 rs35117343 chr3:101445126 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.4 0.49 3.31e-22 Colorectal cancer; LIHC cis rs2204008 0.715 rs11495369 chr12:38238673 T/C cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC cis rs6754311 0.593 rs10202489 chr2:136494186 G/A cg17750252 chr2:136567154 LCT 0.35 6.21 0.32 1.56e-9 Mosquito bite size; LIHC cis rs7089973 0.604 rs1924034 chr10:116578539 C/T cg23260525 chr10:116636907 FAM160B1 0.38 7.44 0.37 8.39e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs561341 1.000 rs117029332 chr17:30266085 C/G cg20587970 chr11:113659929 NA -1.46 -11.99 -0.54 6.92e-28 Hip circumference adjusted for BMI; LIHC cis rs4788570 0.615 rs7190487 chr16:71648617 A/G cg06353428 chr16:71660113 MARVELD3 1.43 14.44 0.62 2.98e-37 Intelligence (multi-trait analysis); LIHC cis rs9682041 0.932 rs9841852 chr3:170067049 C/G cg11886554 chr3:170076028 SKIL 0.78 6.63 0.34 1.32e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs9296092 0.538 rs62407565 chr6:33535739 A/G cg13560919 chr6:33536144 NA -0.41 -6.82 -0.35 4.06e-11 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05463257 chr3:182782445 MCCC1 0.47 6.3 0.32 9.08e-10 Hepatitis; LIHC cis rs2176862 1.000 rs2293023 chr3:46620899 T/A cg08058988 chr3:46621936 LRRC2;TDGF1 -0.61 -6.3 -0.32 9.3e-10 Plasma amyloid beta peptide concentrations (ABx-42); LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg14004847 chr7:1930337 MAD1L1 -0.42 -5.97 -0.31 6.01e-9 Bipolar disorder and schizophrenia; LIHC cis rs769267 0.792 rs4808961 chr19:19577215 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.81 0.39 6.89e-14 Tonsillectomy; LIHC trans rs9951602 0.541 rs7243702 chr18:76645637 G/A cg02800362 chr5:177631904 HNRNPAB 0.66 10.47 0.49 1.89e-22 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04077199 chr22:24989175 GGT1;C22orf36 0.47 6.33 0.32 7.61e-10 Lung function (FEV1/FVC); LIHC cis rs1577917 1.000 rs12154056 chr6:86634094 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs9303401 0.659 rs12946852 chr17:57013337 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.34 0.55 3.55e-29 Cognitive test performance; LIHC cis rs600806 0.850 rs1465607 chr1:109958035 T/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.92 -0.3 7.87e-9 Intelligence (multi-trait analysis); LIHC cis rs7412746 0.658 rs2864869 chr1:150734655 G/A cg17724175 chr1:150552817 MCL1 0.48 9.3 0.45 1.65e-18 Melanoma; LIHC cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.89 12.93 0.57 2.06e-31 Alzheimer's disease; LIHC cis rs7188697 0.922 rs28307 chr16:58577138 A/C cg02549819 chr16:58548995 SETD6 -0.46 -7.27 -0.37 2.47e-12 QT interval; LIHC cis rs6582630 0.519 rs11495700 chr12:38288240 A/G cg26384229 chr12:38710491 ALG10B 0.86 10.73 0.5 2.4e-23 Drug-induced liver injury (flucloxacillin); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10620767 chr10:300254 ZMYND11 -0.25 -6.04 -0.31 3.94e-9 Calcium levels; LIHC cis rs1005277 0.579 rs1780138 chr10:38501654 A/G cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs3736485 0.873 rs12442725 chr15:51874412 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9486715 0.867 rs9384602 chr6:96919561 G/A cg06623918 chr6:96969491 KIAA0776 0.83 14.54 0.62 1.28e-37 Headache; LIHC cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg25204440 chr1:209979598 IRF6 0.53 8.08 0.4 1.15e-14 Cleft lip with or without cleft palate; LIHC cis rs2404602 0.735 rs11629888 chr15:76719880 A/T cg23625390 chr15:77176239 SCAPER -0.47 -7.72 -0.39 1.33e-13 Blood metabolite levels; LIHC cis rs7617480 0.549 rs9879978 chr3:48846600 T/G cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.45 0.33 3.75e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg06873352 chr17:61820015 STRADA 0.72 12.52 0.56 7.08e-30 Prudent dietary pattern; LIHC cis rs9918079 0.560 rs6414767 chr4:15655721 A/G cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.85 -0.3 1.16e-8 Obesity-related traits; LIHC trans rs637571 0.676 rs1151523 chr11:65665200 C/T cg17712092 chr4:129076599 LARP1B -0.76 -11.83 -0.54 2.63e-27 Eosinophil percentage of white cells; LIHC cis rs7551222 0.752 rs4252694 chr1:204499056 A/G cg20240347 chr1:204465584 NA -0.36 -7.5 -0.38 5.47e-13 Schizophrenia; LIHC cis rs60871478 1.000 rs34260834 chr7:822958 A/G cg05535760 chr7:792225 HEATR2 0.75 10.64 0.5 4.85e-23 Cerebrospinal P-tau181p levels; LIHC cis rs7937682 0.924 rs10891283 chr11:111527672 A/G cg09085632 chr11:111637200 PPP2R1B -1.04 -13.22 -0.58 1.56e-32 Primary sclerosing cholangitis; LIHC cis rs8177179 1.000 rs8177179 chr3:133463457 G/A cg16262614 chr3:133464971 TF 0.45 10.18 0.48 1.97e-21 Iron status biomarkers (transferrin levels); LIHC cis rs11098499 0.909 rs79026312 chr4:120440677 C/A cg09307838 chr4:120376055 NA 0.77 11.85 0.54 2.25e-27 Corneal astigmatism; LIHC cis rs2073300 1.000 rs79255223 chr20:23443559 G/T cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs763121 0.853 rs9607566 chr22:39075434 C/G cg06022373 chr22:39101656 GTPBP1 0.65 11.25 0.52 3.49e-25 Menopause (age at onset); LIHC cis rs595982 0.527 rs73061656 chr19:49372355 G/A cg21252483 chr19:49399788 TULP2 -0.92 -10.12 -0.48 3.02e-21 Red cell distribution width; LIHC cis rs6691722 0.503 rs3765431 chr1:24706410 T/C cg18323236 chr1:24743029 NIPAL3 0.39 7.25 0.37 2.73e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs7927592 0.913 rs7102898 chr11:68328870 G/A cg20283391 chr11:68216788 NA -0.51 -7.65 -0.38 2.04e-13 Total body bone mineral density; LIHC cis rs10504229 0.679 rs72649114 chr8:58037491 G/T cg02290350 chr8:58132656 NA 0.31 7.15 0.36 5.41e-12 Developmental language disorder (linguistic errors); LIHC cis rs7845219 0.544 rs6987400 chr8:95921295 T/C cg16049864 chr8:95962084 TP53INP1 -0.44 -6.43 -0.33 4.24e-10 Type 2 diabetes; LIHC cis rs780096 0.546 rs1528533 chr2:27595756 G/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.27 -0.32 1.09e-9 Total body bone mineral density; LIHC cis rs854572 1.000 rs854572 chr7:94954696 C/G cg19678392 chr7:94953810 PON1 -0.64 -11.92 -0.54 1.26e-27 Paraoxonase activity; LIHC cis rs9457247 0.602 rs12208359 chr6:167458455 G/A cg07741184 chr6:167504864 NA 0.35 7.94 0.39 2.85e-14 Crohn's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15754109 chr8:67974431 COPS5 0.43 6.97 0.35 1.59e-11 Cognitive function; LIHC cis rs10751667 0.643 rs7395613 chr11:933873 C/T cg10932868 chr11:921992 NA 0.38 7.32 0.37 1.83e-12 Alzheimer's disease (late onset); LIHC cis rs1559088 1.000 rs2161225 chr19:33551899 C/T cg27124370 chr19:33622961 WDR88 0.46 7.05 0.36 9.79e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs67478160 0.643 rs8004408 chr14:104203938 G/A cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.57 -0.38 3.57e-13 Schizophrenia; LIHC cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg08067268 chr2:26466485 HADHB;HADHA -0.4 -6.38 -0.33 5.92e-10 Gut microbiome composition (summer); LIHC cis rs11212260 0.512 rs17663749 chr11:107185075 G/A cg25435332 chr11:107328525 CWF19L2 0.75 6.96 0.35 1.77e-11 IgG glycosylation; LIHC cis rs12440869 0.649 rs4776929 chr15:67707134 G/C cg21788615 chr15:67813140 C15orf61 -0.42 -6.25 -0.32 1.22e-9 Peak velocity of the mitral A-wave; LIHC cis rs796364 0.806 rs79333757 chr2:200915716 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs7953508 0.750 rs7977788 chr12:93982332 G/A cg18151635 chr12:93972918 NA -0.43 -6.69 -0.34 9.11e-11 Pubertal anthropometrics; LIHC cis rs1355223 0.872 rs7116409 chr11:34751007 T/G cg11058730 chr11:34937778 PDHX;APIP -0.44 -6.5 -0.33 2.86e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg11502198 chr6:26597334 ABT1 0.6 9.17 0.44 4.39e-18 Intelligence (multi-trait analysis); LIHC cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg17747265 chr1:1875780 NA -0.58 -11.21 -0.52 4.65e-25 Body mass index; LIHC trans rs71658797 0.505 rs35038885 chr1:77960789 A/G cg04606550 chr5:14226569 TRIO 0.39 6.14 0.32 2.25e-9 Lung cancer in ever smokers;Lung cancer;Lung adenocarcinoma; LIHC cis rs7267979 1.000 rs2259926 chr20:25281733 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2842992 0.830 rs2025190 chr6:160138241 C/T cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.37 0.56 2.62e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs72829446 0.530 rs7217492 chr17:7396049 C/G cg02795151 chr17:7402630 POLR2A 0.51 5.8 0.3 1.49e-8 Androgen levels; LIHC cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg11987759 chr7:65425863 GUSB -0.39 -6.17 -0.32 1.88e-9 Calcium levels; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg26338869 chr17:61819248 STRADA 0.61 8.84 0.43 5.28e-17 Prudent dietary pattern; LIHC cis rs2228479 0.618 rs34689166 chr16:89860697 C/T cg04013166 chr16:89971882 TCF25 0.49 5.91 0.3 8.48e-9 Skin colour saturation; LIHC cis rs11098499 0.615 rs28850368 chr4:120554313 G/A cg09307838 chr4:120376055 NA 0.67 10.26 0.49 1.05e-21 Corneal astigmatism; LIHC trans rs12780046 0.656 rs11189963 chr10:100845659 C/T cg05980083 chr9:112191166 PTPN3 -0.47 -6.17 -0.32 1.91e-9 Non-glioblastoma glioma; LIHC cis rs2273669 0.667 rs11153148 chr6:109304084 C/T cg05315195 chr6:109294784 ARMC2 -0.53 -5.83 -0.3 1.29e-8 Prostate cancer; LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg06873352 chr17:61820015 STRADA 0.74 13.44 0.59 2.35e-33 Prudent dietary pattern; LIHC cis rs9814567 0.896 rs7642266 chr3:134346025 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.59 -9.88 -0.47 2.04e-20 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2455799 0.533 rs924754 chr3:15756215 A/T cg12698662 chr3:15914712 MIR563 -0.38 -6.99 -0.35 1.46e-11 Mean platelet volume; LIHC cis rs7584330 0.554 rs77956735 chr2:238399130 C/T cg08992911 chr2:238395768 MLPH 0.58 6.05 0.31 3.89e-9 Prostate cancer; LIHC cis rs2230307 0.536 rs834277 chr1:100510855 T/G cg24955406 chr1:100503596 HIAT1 0.62 6.14 0.32 2.27e-9 Carotid intima media thickness; LIHC cis rs17401966 0.931 rs4846205 chr1:10310214 A/T cg15208524 chr1:10270712 KIF1B 0.4 6.14 0.32 2.26e-9 Hepatocellular carcinoma; LIHC cis rs876084 0.505 rs11988495 chr8:121128487 A/G cg06265175 chr8:121136014 COL14A1 0.42 6.68 0.34 9.71e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8017423 0.565 rs4904681 chr14:90835566 A/T cg14092571 chr14:90743983 NA 0.41 5.76 0.3 1.92e-8 Mortality in heart failure; LIHC cis rs8027181 0.804 rs34661924 chr15:72994564 A/G cg25632853 chr15:73088954 NA 0.35 5.89 0.3 9.09e-9 Triglyceride levels; LIHC cis rs655641 1.000 rs489486 chr11:85765737 T/C cg09030501 chr11:85779252 PICALM -0.52 -6.1 -0.31 2.83e-9 Platelet count; LIHC cis rs3020736 0.500 rs6002605 chr22:42494335 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.08 -0.31 3.15e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.49 0.38 5.79e-13 Bipolar disorder; LIHC cis rs5769707 0.554 rs10854876 chr22:50010570 T/C cg07959070 chr22:50026188 C22orf34 -0.34 -8.39 -0.41 1.29e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs8083850 0.635 rs2043146 chr18:50850992 T/G cg24270629 chr18:50823537 DCC 0.53 7.91 0.39 3.71e-14 Intelligence (multi-trait analysis); LIHC cis rs6748734 1.000 rs11893118 chr2:241828308 C/G cg08694578 chr2:241835147 C2orf54 -0.63 -10.27 -0.49 9.61e-22 Urinary metabolites; LIHC trans rs66887589 0.616 rs13113885 chr4:120221176 G/C cg25214090 chr10:38739885 LOC399744 0.41 6.42 0.33 4.46e-10 Diastolic blood pressure; LIHC cis rs11711311 0.911 rs3773681 chr3:113523901 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.84 -0.35 3.76e-11 IgG glycosylation; LIHC cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg22800045 chr5:56110881 MAP3K1 0.68 8.84 0.43 5.27e-17 Initial pursuit acceleration; LIHC cis rs2204008 0.749 rs4579984 chr12:38166266 A/G cg13010199 chr12:38710504 ALG10B 0.48 5.78 0.3 1.71e-8 Bladder cancer; LIHC cis rs68170813 0.559 rs997311 chr7:106953033 G/A cg02696742 chr7:106810147 HBP1 -0.51 -5.88 -0.3 9.71e-9 Coronary artery disease; LIHC cis rs898097 0.625 rs7406464 chr17:80891460 A/G cg02711726 chr17:80685570 FN3KRP 0.31 5.78 0.3 1.68e-8 Breast cancer; LIHC cis rs7762018 0.607 rs75999653 chr6:170066927 A/G cg19338460 chr6:170058176 WDR27 -0.88 -9.6 -0.46 1.83e-19 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs62458065 0.640 rs79619897 chr7:32514819 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.7 -7.0 -0.35 1.36e-11 Metabolite levels (HVA/MHPG ratio); LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg20295408 chr7:1910781 MAD1L1 -0.49 -7.01 -0.35 1.26e-11 Bipolar disorder and schizophrenia; LIHC cis rs7408868 1.000 rs4809030 chr19:15273381 A/G cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC cis rs7618501 1.000 rs7618519 chr3:49772708 A/T cg21467203 chr3:49911342 NA 0.4 7.0 0.35 1.33e-11 Intelligence (multi-trait analysis); LIHC cis rs8141529 0.778 rs9625566 chr22:29162506 G/A cg15103426 chr22:29168792 CCDC117 0.67 11.25 0.52 3.32e-25 Lymphocyte counts; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg21581283 chr12:124826534 NCOR2 0.42 6.24 0.32 1.27e-9 Alopecia areata; LIHC cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs250677 0.524 rs40521 chr5:148439639 C/T cg18129178 chr5:148520854 ABLIM3 0.36 6.04 0.31 3.97e-9 Breast cancer; LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.07 0.55 3.4e-28 Prudent dietary pattern; LIHC cis rs1062177 0.756 rs2964587 chr5:151119972 C/T cg00977110 chr5:151150581 G3BP1 -0.56 -7.07 -0.36 8.73e-12 Preschool internalizing problems; LIHC cis rs7937890 0.599 rs2597204 chr11:14481017 C/T cg02886208 chr11:14281011 SPON1 -0.51 -6.84 -0.35 3.58e-11 Mitochondrial DNA levels; LIHC cis rs9549367 0.789 rs2287253 chr13:113891075 G/A cg18105134 chr13:113819100 PROZ 0.64 11.15 0.52 7.96e-25 Platelet distribution width; LIHC cis rs10791097 0.739 rs735094 chr11:130725109 G/C cg09137382 chr11:130731461 NA 0.42 6.31 0.32 8.58e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs17253792 1.000 rs28616134 chr14:56178802 G/A cg01858014 chr14:56050164 KTN1 -0.76 -8.08 -0.4 1.1e-14 Putamen volume; LIHC cis rs7635838 0.751 rs6442260 chr3:11590751 C/T cg00170343 chr3:11313890 ATG7 -0.4 -5.87 -0.3 1.03e-8 HDL cholesterol; LIHC cis rs11122272 0.735 rs2790886 chr1:231529491 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs921968 0.643 rs520095 chr2:219329485 C/T cg17980119 chr2:219472607 PLCD4 0.37 6.27 0.32 1.1e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04856096 chr8:68255097 ARFGEF1 0.47 6.19 0.32 1.75e-9 Pancreatic cancer; LIHC cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg09904177 chr6:26538194 HMGN4 0.55 10.84 0.51 9.71e-24 Intelligence (multi-trait analysis); LIHC cis rs507080 0.922 rs555356 chr11:118558078 G/T cg04173919 chr11:118528438 PHLDB1 0.35 6.6 0.34 1.53e-10 Serum metabolite levels; LIHC cis rs875971 1.000 rs6460295 chr7:65882728 T/C cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs12479064 0.724 rs4851203 chr2:99986932 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.45 -6.29 -0.32 9.45e-10 Chronic sinus infection; LIHC cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.58 0.34 1.79e-10 Bipolar disorder; LIHC cis rs5769707 0.605 rs6009791 chr22:50025265 T/C cg01652190 chr22:50026171 C22orf34 -0.34 -7.6 -0.38 2.87e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7647973 0.593 rs7652179 chr3:49808618 T/A cg03060546 chr3:49711283 APEH -0.54 -5.87 -0.3 1.03e-8 Menarche (age at onset); LIHC cis rs9303401 0.659 rs35539277 chr17:56853833 G/A cg25039879 chr17:56429692 SUPT4H1 0.84 9.6 0.46 1.72e-19 Cognitive test performance; LIHC cis rs1707322 0.963 rs10789484 chr1:46406978 G/C cg06784218 chr1:46089804 CCDC17 0.35 6.36 0.33 6.39e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12594515 1.000 rs7172161 chr15:45990780 A/G cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC cis rs4665809 0.941 rs3177055 chr2:26359315 G/A cg04944784 chr2:26401820 FAM59B -0.68 -8.58 -0.42 3.25e-16 Gut microbiome composition (summer); LIHC cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg18306943 chr3:40428807 ENTPD3 0.42 7.46 0.37 7.04e-13 Renal cell carcinoma; LIHC cis rs6977660 0.714 rs12666488 chr7:19788403 G/A cg07541023 chr7:19748670 TWISTNB 0.49 7.24 0.36 2.93e-12 Thyroid stimulating hormone; LIHC cis rs6952808 0.729 rs35797753 chr7:1954914 G/A cg02951883 chr7:2050386 MAD1L1 -0.59 -8.71 -0.43 1.3e-16 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23002097 chr19:58898625 RPS5 -0.48 -6.61 -0.34 1.46e-10 Pancreatic cancer; LIHC cis rs6815814 0.851 rs11466645 chr4:38778203 A/T cg06935464 chr4:38784597 TLR10 0.5 7.76 0.39 1e-13 Breast cancer; LIHC cis rs5758511 0.680 rs1107554 chr22:42667594 C/G cg00645731 chr22:42541494 CYP2D7P1 0.51 8.14 0.4 7.35e-15 Birth weight; LIHC cis rs2645694 0.603 rs2703123 chr4:77821154 C/T cg06046430 chr4:77819534 ANKRD56 0.5 6.53 0.33 2.34e-10 Emphysema distribution in smoking; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08037059 chr1:90460796 LOC492303;ZNF326 0.5 6.59 0.34 1.71e-10 Lung function (FEV1/FVC); LIHC cis rs2404602 0.583 rs12438741 chr15:76542114 C/A cg23625390 chr15:77176239 SCAPER 0.35 6.02 0.31 4.55e-9 Blood metabolite levels; LIHC cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg22168489 chr12:122356033 WDR66 0.45 6.2 0.32 1.61e-9 Mean corpuscular volume; LIHC cis rs9660992 0.762 rs1172130 chr1:205244953 G/A cg21545522 chr1:205238299 TMCC2 0.29 5.93 0.31 7.36e-9 Mean corpuscular volume;Mean platelet volume; LIHC cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.38e-12 Bipolar disorder; LIHC cis rs138880 0.542 rs9616210 chr22:50317346 C/T cg02269571 chr22:50332266 NA -0.96 -9.93 -0.47 1.42e-20 Schizophrenia; LIHC cis rs6061231 0.724 rs1570027 chr20:60968596 A/G cg24112000 chr20:60950667 NA -0.62 -8.2 -0.41 4.91e-15 Colorectal cancer; LIHC cis rs12893668 0.703 rs35498576 chr14:104025893 T/C cg24130564 chr14:104152367 KLC1 -0.54 -8.89 -0.43 3.49e-17 Reticulocyte count; LIHC cis rs7512552 0.809 rs2794685 chr1:150312268 C/T cg15654264 chr1:150340011 RPRD2 0.7 11.46 0.53 5.82e-26 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2153535 0.580 rs7775909 chr6:8477778 A/G cg07606381 chr6:8435919 SLC35B3 0.82 12.33 0.55 3.65e-29 Motion sickness; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05787120 chr3:50365854 TUSC2 -0.49 -6.32 -0.32 8.1e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.49 -0.33 2.94e-10 Total body bone mineral density; LIHC cis rs240764 0.584 rs11155653 chr6:101217123 G/A cg09795085 chr6:101329169 ASCC3 -0.55 -7.66 -0.38 1.99e-13 Neuroticism; LIHC cis rs6570726 0.935 rs388394 chr6:145852689 C/T cg23711669 chr6:146136114 FBXO30 0.53 9.31 0.45 1.55e-18 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14497545 chr4:140754475 MAML3 0.43 6.89 0.35 2.77e-11 Cognitive function; LIHC cis rs919433 0.929 rs4850788 chr2:198182940 G/A cg10820045 chr2:198174542 NA -0.6 -10.14 -0.48 2.7e-21 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs10751667 0.666 rs4074233 chr11:977685 G/A cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs637571 0.522 rs12797319 chr11:65735672 G/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.39 5.82 0.3 1.38e-8 Eosinophil percentage of white cells; LIHC cis rs8070463 0.515 rs11655943 chr17:45385640 A/G cg08085267 chr17:45401833 C17orf57 -0.56 -8.2 -0.41 5e-15 Multiple sclerosis;Ankylosing spondylitis; LIHC cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs8044995 0.501 rs73613952 chr16:68352808 G/C cg09835421 chr16:68378352 PRMT7 -0.84 -9.61 -0.46 1.68e-19 Schizophrenia; LIHC cis rs7520050 0.833 rs1085242 chr1:46544224 T/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.92 0.3 8.01e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7927771 0.832 rs4752993 chr11:47410951 T/C cg20135002 chr11:47629003 NA 0.54 9.06 0.44 1.03e-17 Subjective well-being; LIHC cis rs4919694 0.808 rs4918001 chr10:105013147 G/T cg04362960 chr10:104952993 NT5C2 -0.83 -6.73 -0.34 7.33e-11 Arsenic metabolism; LIHC cis rs713477 1.000 rs12887846 chr14:55911139 T/C cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.64e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs6754311 0.551 rs9287442 chr2:136522710 A/G cg07305463 chr2:136567211 LCT 0.37 6.56 0.33 2.01e-10 Mosquito bite size; LIHC cis rs5769765 1.000 rs34774661 chr22:50267508 C/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg25894440 chr7:65020034 NA -0.57 -6.4 -0.33 5e-10 Diabetic kidney disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00218103 chr22:46465977 NA 0.36 6.38 0.33 5.81e-10 Cognitive function; LIHC cis rs6762477 0.748 rs9831967 chr3:50217234 C/T cg21467203 chr3:49911342 NA 0.4 7.2 0.36 3.97e-12 Menarche (age at onset); LIHC cis rs9818758 0.556 rs13086240 chr3:49001409 G/A cg00383909 chr3:49044727 WDR6 0.96 7.95 0.4 2.65e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs60871478 0.730 rs62432226 chr7:792973 T/C cg11064039 chr7:766100 PRKAR1B;HEATR2 0.51 5.73 0.3 2.25e-8 Cerebrospinal P-tau181p levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01949614 chr16:1359397 UBE2I 0.39 6.15 0.32 2.11e-9 Lung function (FEV1/FVC); LIHC cis rs2243480 0.901 rs35823062 chr7:65965821 A/G cg12463550 chr7:65579703 CRCP 0.65 6.76 0.34 5.98e-11 Diabetic kidney disease; LIHC cis rs3008870 0.755 rs2815365 chr1:67499628 C/T cg02640540 chr1:67518911 SLC35D1 0.45 6.98 0.35 1.56e-11 Lymphocyte percentage of white cells; LIHC cis rs8062405 0.755 rs4787456 chr16:28559573 C/T cg07451762 chr16:28383216 NA 0.39 7.05 0.36 9.95e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs922107 0.738 rs12760395 chr1:90040361 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.6 -0.38 2.8e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs611744 0.967 rs645070 chr8:109216345 A/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.77e-11 Dupuytren's disease; LIHC cis rs875971 0.522 rs709604 chr7:65497434 A/G cg00343986 chr7:65444356 GUSB -0.44 -6.18 -0.32 1.84e-9 Aortic root size; LIHC cis rs2115630 0.645 rs3825877 chr15:85174631 G/A cg12501888 chr15:85177176 SCAND2 -0.46 -6.99 -0.35 1.49e-11 P wave terminal force; LIHC cis rs6502050 0.835 rs8067138 chr17:80111026 T/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs7953508 0.506 rs1316740 chr12:93968288 C/A cg18151635 chr12:93972918 NA -0.51 -8.58 -0.42 3.4e-16 Pubertal anthropometrics; LIHC cis rs2072499 0.750 rs7534339 chr1:156156219 A/G cg25208724 chr1:156163844 SLC25A44 0.71 7.9 0.39 3.97e-14 Testicular germ cell tumor; LIHC trans rs6598955 0.671 rs10902727 chr1:26597781 C/T cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs9611565 0.580 rs5758449 chr22:42140160 C/T cg06634786 chr22:41940651 POLR3H 0.58 6.43 0.33 4.23e-10 Vitiligo; LIHC trans rs9388451 0.626 rs3799712 chr6:126075103 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.66 -10.92 -0.51 5.2e-24 Brugada syndrome; LIHC cis rs7914558 0.966 rs746293 chr10:104897254 G/T cg15744005 chr10:104629667 AS3MT -0.39 -8.69 -0.43 1.5e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7677751 0.806 rs1800813 chr4:55094467 G/A cg17187183 chr4:55093834 PDGFRA 0.67 8.37 0.41 1.52e-15 Corneal astigmatism; LIHC cis rs12762955 0.507 rs7095853 chr10:1040798 T/C cg26597838 chr10:835615 NA -0.46 -5.71 -0.3 2.44e-8 Response to angiotensin II receptor blocker therapy; LIHC cis rs9549328 0.800 rs9549326 chr13:113630453 C/T cg00071026 chr13:113650936 MCF2L -0.39 -6.0 -0.31 5.1e-9 Systolic blood pressure; LIHC cis rs2645694 0.626 rs2703124 chr4:77820626 G/T cg03477792 chr4:77819574 ANKRD56 0.6 8.77 0.43 8.32e-17 Emphysema distribution in smoking; LIHC cis rs3106136 0.843 rs7438414 chr4:95265822 T/C cg11021082 chr4:95130006 SMARCAD1 0.4 7.18 0.36 4.31e-12 Capecitabine sensitivity; LIHC trans rs7613875 0.578 rs4688753 chr3:50074773 A/G cg21659725 chr3:3221576 CRBN -0.55 -8.16 -0.4 6.51e-15 Body mass index; LIHC cis rs3791556 0.741 rs3791542 chr2:240103955 A/G cg03281426 chr2:240109471 HDAC4 -0.38 -5.85 -0.3 1.16e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2180341 0.814 rs6919082 chr6:127737888 T/G cg27446573 chr6:127587934 RNF146 0.78 12.56 0.56 5.05e-30 Breast cancer; LIHC cis rs425277 0.917 rs78609670 chr1:2045886 G/T cg24578937 chr1:2090814 PRKCZ 0.45 7.39 0.37 1.13e-12 Height; LIHC trans rs2243480 0.901 rs12530490 chr7:65691647 G/A cg10756647 chr7:56101905 PSPH -1.04 -12.56 -0.56 5.34e-30 Diabetic kidney disease; LIHC cis rs6430585 0.528 rs115553816 chr2:136692893 G/A cg25344623 chr2:136566232 LCT -0.37 -5.98 -0.31 5.65e-9 Corneal structure; LIHC cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC cis rs1059312 0.808 rs4760533 chr12:129297651 A/G cg21616243 chr12:129299702 MGC16384;SLC15A4 0.73 16.36 0.66 7.76e-45 Systemic lupus erythematosus; LIHC cis rs9378688 0.654 rs2479008 chr6:2347808 C/T cg12303981 chr6:2244766 GMDS -0.43 -5.88 -0.3 9.96e-9 Caudate nucleus volume; LIHC cis rs7674212 0.570 rs2711898 chr4:104063071 C/T cg16532752 chr4:104119610 CENPE -0.45 -7.11 -0.36 6.96e-12 Type 2 diabetes; LIHC cis rs7520050 0.966 rs12021587 chr1:46472759 G/T cg03146154 chr1:46216737 IPP -0.38 -6.21 -0.32 1.5e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6912958 0.703 rs9362427 chr6:88097634 G/T cg12350822 chr6:88032061 C6orf162;GJB7 0.4 7.99 0.4 2.13e-14 Monocyte percentage of white cells; LIHC cis rs2228479 0.850 rs11640209 chr16:89807828 C/A cg19635926 chr16:89946313 TCF25 0.49 6.21 0.32 1.5e-9 Skin colour saturation; LIHC cis rs635808 0.500 rs1964808 chr6:167172602 C/T cg05573767 chr6:167171394 RPS6KA2 0.34 7.16 0.36 4.91e-12 Dental caries; LIHC cis rs6754311 0.731 rs7579771 chr2:136580260 T/A cg07305463 chr2:136567211 LCT -0.39 -7.59 -0.38 3.11e-13 Mosquito bite size; LIHC cis rs6690583 0.623 rs61768853 chr1:85455707 T/C cg22153463 chr1:85462885 MCOLN2 0.49 5.91 0.3 8.45e-9 Serum sulfate level; LIHC cis rs10089 1.000 rs4835941 chr5:127430905 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.86 0.35 3.28e-11 Ileal carcinoids; LIHC cis rs2549003 1.000 rs10214312 chr5:131821866 T/G cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07849438 chr12:19593035 AEBP2 -0.48 -6.53 -0.33 2.45e-10 Hepatitis; LIHC cis rs77633900 0.614 rs2469244 chr15:76884127 G/A cg21673338 chr15:77095150 SCAPER -0.5 -7.24 -0.36 2.93e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs6542838 0.609 rs12712043 chr2:99541494 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.42 -5.98 -0.31 5.75e-9 Fear of minor pain; LIHC cis rs4925386 0.802 rs6142735 chr20:60918087 G/C cg24112000 chr20:60950667 NA -0.46 -6.11 -0.31 2.69e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs911119 1.000 rs6036478 chr20:23611359 C/A cg16589663 chr20:23618590 CST3 0.74 7.51 0.38 5.16e-13 Chronic kidney disease; LIHC cis rs2153535 0.563 rs1737584 chr6:8536742 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.41 0.41 1.11e-15 Motion sickness; LIHC cis rs600806 0.778 rs10776698 chr1:110013630 C/T cg23091122 chr1:110024289 SYPL2 -0.5 -6.83 -0.35 3.93e-11 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg10755058 chr3:40428713 ENTPD3 0.41 7.06 0.36 9.06e-12 Renal cell carcinoma; LIHC cis rs7575217 0.767 rs796056 chr2:101735276 A/C cg23907051 chr2:101730305 TBC1D8 -0.26 -5.83 -0.3 1.29e-8 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; LIHC cis rs7100689 0.646 rs7077854 chr10:82124070 C/T cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg16497277 chr3:49208875 KLHDC8B -0.49 -6.13 -0.31 2.46e-9 Menarche (age at onset); LIHC cis rs1008375 0.966 rs6839660 chr4:17667987 C/T cg02297831 chr4:17616191 MED28 0.39 6.13 0.31 2.37e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8180040 0.620 rs2305635 chr3:47043622 G/A cg16586182 chr3:47516702 SCAP 0.47 8.57 0.42 3.56e-16 Colorectal cancer; LIHC cis rs1577917 0.958 rs10944168 chr6:86680156 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.82 -0.35 4.04e-11 Response to antipsychotic treatment; LIHC cis rs12477438 0.748 rs6712773 chr2:99585781 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.71 -0.65 3.04e-42 Chronic sinus infection; LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg27432699 chr2:27873401 GPN1 -0.5 -7.27 -0.37 2.39e-12 Menopause (age at onset); LIHC cis rs2303759 0.918 rs9749416 chr19:49885005 G/A cg22307029 chr19:49891270 CCDC155 0.56 9.03 0.44 1.33e-17 Multiple sclerosis; LIHC trans rs75804782 0.521 rs55988884 chr2:239396930 G/A cg01134436 chr17:81009848 B3GNTL1 0.82 6.89 0.35 2.67e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs2197308 0.728 rs7304305 chr12:37932990 T/C cg26384229 chr12:38710491 ALG10B -0.47 -6.64 -0.34 1.23e-10 Morning vs. evening chronotype; LIHC cis rs2857078 0.720 rs9906669 chr17:42305706 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.41 7.29 0.37 2.14e-12 Red cell distribution width;Reticulocyte count; LIHC trans rs7613875 0.620 rs2526747 chr3:50082914 C/G cg21659725 chr3:3221576 CRBN 0.53 7.86 0.39 5.05e-14 Body mass index; LIHC cis rs10744422 1.000 rs4759387 chr12:123377569 C/T cg22842854 chr12:123319900 HIP1R -0.61 -7.54 -0.38 4.32e-13 Schizophrenia; LIHC cis rs9303401 0.659 rs62083368 chr17:56878062 G/A cg25039879 chr17:56429692 SUPT4H1 0.77 8.91 0.43 3e-17 Cognitive test performance; LIHC cis rs6088590 1.000 rs6088595 chr20:33358499 T/A cg06115741 chr20:33292138 TP53INP2 0.63 8.68 0.42 1.69e-16 Coronary artery disease; LIHC cis rs7412746 0.658 rs11581757 chr1:150892244 A/G cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs7927592 0.913 rs7127948 chr11:68363062 G/A cg20283391 chr11:68216788 NA -0.52 -7.72 -0.39 1.27e-13 Total body bone mineral density; LIHC cis rs79057730 0.599 rs4721086 chr7:821123 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.82 9.5 0.46 3.78e-19 Initial pursuit acceleration; LIHC cis rs6570726 0.935 rs409725 chr6:145840340 G/A cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs2838855 chr21:46680566 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.73 -11.5 -0.53 4.37e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs916888 0.773 rs199451 chr17:44801784 G/A cg26692224 chr17:62915920 LRRC37A3 -0.73 -6.98 -0.35 1.5e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs826838 1.000 rs11183941 chr12:38851692 G/C cg26384229 chr12:38710491 ALG10B 0.98 13.29 0.58 8.46e-33 Heart rate; LIHC cis rs9649213 0.574 rs7791321 chr7:97944125 G/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.92 -0.3 7.89e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs2153535 0.580 rs1119688 chr6:8460850 T/C cg21535247 chr6:8435926 SLC35B3 0.63 8.24 0.41 3.75e-15 Motion sickness; LIHC cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC trans rs79243044 0.786 rs16932549 chr11:5560909 C/T cg05947499 chr12:113704091 TPCN1 0.45 6.17 0.32 1.91e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs9733 0.596 rs12086630 chr1:150650955 T/C cg17724175 chr1:150552817 MCL1 0.47 9.51 0.46 3.45e-19 Tonsillectomy; LIHC cis rs10056811 0.527 rs55798253 chr5:74380957 A/G cg00601450 chr5:74908170 NA 0.55 6.36 0.33 6.46e-10 Coronary artery disease; LIHC cis rs7131987 0.650 rs7311912 chr12:29475703 G/C cg12903224 chr12:29470962 FAR2 -0.41 -6.65 -0.34 1.14e-10 QT interval; LIHC cis rs116095464 0.558 rs112343653 chr5:257174 G/A cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs763121 0.849 rs12004 chr22:38877461 T/G cg14440974 chr22:39074834 NA -0.37 -5.86 -0.3 1.08e-8 Menopause (age at onset); LIHC cis rs7613875 0.578 rs2526749 chr3:50076734 A/G cg21467203 chr3:49911342 NA 0.52 9.35 0.45 1.18e-18 Body mass index; LIHC cis rs12048904 0.964 rs8888 chr1:101338324 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.54 8.7 0.43 1.43e-16 Multiple sclerosis; LIHC cis rs7395581 1.000 rs7395581 chr11:47246397 G/A cg26139080 chr11:47293733 MADD 0.49 8.08 0.4 1.15e-14 HDL cholesterol; LIHC cis rs9733 0.596 rs12086472 chr1:150697710 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 -0.87 -9.06 -0.44 1.04e-17 Platelet count; LIHC cis rs9640161 0.636 rs56190213 chr7:150025720 T/C cg27494647 chr7:150038898 RARRES2 0.33 5.98 0.31 5.68e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs600806 0.821 rs3879451 chr1:109909269 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC trans rs8002861 0.935 rs1819595 chr13:44429716 T/A cg17145862 chr1:211918768 LPGAT1 0.58 10.97 0.51 3.39e-24 Leprosy; LIHC trans rs916888 0.697 rs199516 chr17:44856485 C/T cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs8017423 0.630 rs12589687 chr14:90819570 C/G cg04374321 chr14:90722782 PSMC1 -0.51 -7.44 -0.37 8.31e-13 Mortality in heart failure; LIHC cis rs787274 0.681 rs787284 chr9:115538040 A/G cg13803584 chr9:115635662 SNX30 -0.56 -6.25 -0.32 1.21e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7772486 0.875 rs9322045 chr6:146384950 C/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.92 -0.3 7.75e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 0.635 rs73071706 chr3:40288190 C/A cg00656387 chr3:40428638 ENTPD3 0.45 7.27 0.37 2.44e-12 Renal cell carcinoma; LIHC cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg02951883 chr7:2050386 MAD1L1 -0.7 -11.6 -0.53 1.92e-26 Schizophrenia; LIHC cis rs4450131 0.898 rs10794173 chr10:126330565 C/T cg20435097 chr10:126320824 FAM53B -0.53 -9.58 -0.46 2.01e-19 White blood cell count (basophil); LIHC cis rs9902453 0.967 rs12150261 chr17:28320473 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.48 -0.53 5.04e-26 Coffee consumption (cups per day); LIHC cis rs7772486 0.790 rs6570724 chr6:146151283 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.49 0.53 4.8e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9911578 1.000 rs4482353 chr17:56896834 A/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.69 -0.43 1.55e-16 Intelligence (multi-trait analysis); LIHC trans rs9914544 0.545 rs12452289 chr17:18781809 T/G cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.75e-10 Educational attainment (years of education); LIHC cis rs963731 0.649 rs2278912 chr2:39199702 C/T cg04010122 chr2:39346883 SOS1 -0.72 -5.97 -0.31 5.85e-9 Corticobasal degeneration; LIHC cis rs3845702 0.736 rs6722147 chr2:180829704 G/A cg01881094 chr2:180872142 CWC22 -1.13 -9.96 -0.47 1.12e-20 Schizophrenia; LIHC cis rs4586057 0.514 rs10785974 chr10:92627931 T/C cg14313238 chr10:92632228 RPP30 0.37 6.15 0.32 2.2e-9 Economic and political preferences (time); LIHC trans rs208520 0.690 rs10455194 chr6:66743356 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.93 0.43 2.63e-17 Exhaled nitric oxide output; LIHC cis rs1707322 1.000 rs34446427 chr1:46417655 A/C cg06784218 chr1:46089804 CCDC17 0.36 6.44 0.33 3.94e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg05368731 chr17:41323189 NBR1 0.73 12.56 0.56 5.19e-30 Menopause (age at onset); LIHC cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg11861562 chr11:117069780 TAGLN 0.49 8.11 0.4 9.18e-15 Blood protein levels; LIHC cis rs11608355 0.618 rs2075435 chr12:109796832 C/T cg19025524 chr12:109796872 NA -0.32 -6.09 -0.31 3.11e-9 Neuroticism; LIHC trans rs2727020 0.894 rs2866361 chr11:49372481 A/G cg03929089 chr4:120376271 NA -0.66 -9.86 -0.47 2.31e-20 Coronary artery disease; LIHC trans rs1814175 0.588 rs1794144 chr11:49918233 A/G cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs4919087 1.000 rs10786330 chr10:99074959 C/A cg25902810 chr10:99078978 FRAT1 0.71 10.7 0.5 3.12e-23 Monocyte count; LIHC trans rs4650994 0.525 rs2493858 chr1:178541210 A/G cg05059571 chr16:84539110 KIAA1609 -0.45 -7.41 -0.37 9.97e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs1577917 0.958 rs12215265 chr6:86443969 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.44 -0.42 9.26e-16 Response to antipsychotic treatment; LIHC cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg02475777 chr4:1388615 CRIPAK -0.51 -7.49 -0.38 6.1e-13 Longevity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04590956 chr2:70057467 GMCL1 0.42 6.15 0.32 2.22e-9 Pancreatic cancer; LIHC cis rs2354432 0.599 rs4950423 chr1:146854539 T/C cg25205988 chr1:146714368 CHD1L 0.84 9.54 0.46 2.78e-19 Mitochondrial DNA levels; LIHC cis rs9583531 0.689 rs9521913 chr13:111382058 C/T cg24331049 chr13:111365604 ING1 -0.73 -11.93 -0.54 1.14e-27 Coronary artery disease; LIHC cis rs6831352 0.589 rs1133483 chr4:100023923 G/C cg12011299 chr4:100065546 ADH4 0.54 12.75 0.57 9.76e-31 Alcohol dependence; LIHC cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg11764359 chr7:65958608 NA 0.58 6.08 0.31 3.18e-9 Diabetic kidney disease; LIHC cis rs2629540 0.847 rs12247543 chr10:126419743 G/C cg20435097 chr10:126320824 FAM53B -0.43 -6.41 -0.33 4.91e-10 Cocaine dependence; LIHC trans rs3942852 0.726 rs1503171 chr11:48175152 T/C cg15704280 chr7:45808275 SEPT13 -0.59 -8.01 -0.4 1.77e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs6750047 0.691 rs336032 chr2:38264788 T/C cg07380506 chr2:38303506 CYP1B1 -0.5 -5.82 -0.3 1.38e-8 Cutaneous malignant melanoma;Melanoma; LIHC cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg26939375 chr7:64535504 NA -0.46 -7.06 -0.36 9.29e-12 Aortic root size; LIHC cis rs2072499 0.750 rs72708291 chr1:156177285 A/T cg24450063 chr1:156163899 SLC25A44 0.75 8.0 0.4 1.96e-14 Testicular germ cell tumor; LIHC cis rs17125944 0.505 rs74642116 chr14:53213507 A/G cg00686598 chr14:53173677 PSMC6 1.21 15.28 0.64 1.46e-40 Alzheimer's disease (late onset); LIHC cis rs3096299 0.591 rs748940 chr16:89440757 T/A cg02187348 chr16:89574699 SPG7 0.42 6.11 0.31 2.68e-9 Multiple myeloma (IgH translocation); LIHC cis rs2153535 0.580 rs4639392 chr6:8446547 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC cis rs6570726 0.935 rs401888 chr6:145831535 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs1892700 0.821 rs61739710 chr21:34925689 G/A cg14850771 chr21:34775459 IFNGR2 -0.44 -5.84 -0.3 1.21e-8 Educational attainment; LIHC cis rs3796352 1.000 rs61172708 chr3:52996052 T/G cg04865290 chr3:52927548 TMEM110 -0.51 -5.9 -0.3 8.82e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs67311347 1.000 rs9848083 chr3:40466979 A/G cg18306943 chr3:40428807 ENTPD3 -0.34 -6.02 -0.31 4.59e-9 Renal cell carcinoma; LIHC trans rs7615952 0.932 rs13321217 chr3:125631771 G/A cg07211511 chr3:129823064 LOC729375 -0.83 -10.68 -0.5 3.56e-23 Blood pressure (smoking interaction); LIHC cis rs2072438 0.503 rs2146838 chr9:123876305 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.44 -6.1 -0.31 2.84e-9 Rheumatoid arthritis; LIHC cis rs12602486 1.000 rs16940540 chr17:42229702 C/A cg13607699 chr17:42295918 UBTF -0.75 -6.42 -0.33 4.46e-10 Glycated hemoglobin levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg12666227 chr12:76742354 BBS10 -0.46 -7.13 -0.36 6.11e-12 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs12824058 0.707 rs2398509 chr12:130816464 T/C cg24229701 chr12:130821962 PIWIL1 0.45 6.74 0.34 6.91e-11 Menopause (age at onset); LIHC cis rs56235845 0.694 rs6860069 chr5:176755841 C/T cg16006841 chr5:176797999 RGS14 0.59 7.85 0.39 5.3e-14 Hemoglobin concentration;Hematocrit; LIHC cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg02244288 chr16:89573955 SPG7 -0.3 -5.8 -0.3 1.49e-8 Multiple myeloma (IgH translocation); LIHC cis rs4665809 1.000 rs6749855 chr2:26255263 A/G cg04944784 chr2:26401820 FAM59B -0.67 -8.28 -0.41 2.81e-15 Gut microbiome composition (summer); LIHC cis rs9911578 1.000 rs2567911 chr17:56734977 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs1534166 0.647 rs9876158 chr3:133508300 T/C cg27366882 chr3:133540807 NA -0.43 -7.24 -0.36 2.95e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs35883536 0.506 rs2809814 chr1:101031829 C/T cg14515779 chr1:101123966 NA -0.42 -6.0 -0.31 5.13e-9 Monocyte count; LIHC cis rs35883536 1.000 rs9803842 chr1:101134877 G/T cg14515779 chr1:101123966 NA -0.7 -14.1 -0.61 6.72e-36 Monocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20112827 chr22:30783793 RNF215 0.42 6.1 0.31 2.87e-9 Lung function (FEV1/FVC); LIHC cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg02931644 chr1:25747376 RHCE 0.35 7.85 0.39 5.29e-14 Erythrocyte sedimentation rate; LIHC cis rs9381040 0.655 rs9381031 chr6:41044957 A/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.79 -0.3 1.58e-8 Alzheimer's disease (late onset); LIHC trans rs3808502 0.527 rs2736374 chr8:11113828 A/G cg24829772 chr8:18577488 PSD3 -0.41 -6.13 -0.31 2.35e-9 Neuroticism; LIHC cis rs8180040 0.615 rs13062681 chr3:47021124 A/G cg27129171 chr3:47204927 SETD2 0.62 10.68 0.5 3.62e-23 Colorectal cancer; LIHC cis rs9560113 1.000 rs61967684 chr13:112178026 G/C cg14154082 chr13:112174009 NA 0.29 6.14 0.32 2.28e-9 Menarche (age at onset); LIHC cis rs9303401 0.659 rs17222621 chr17:56695923 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC trans rs11098499 0.754 rs1814813 chr4:120258207 G/T cg25214090 chr10:38739885 LOC399744 -0.48 -7.8 -0.39 7.42e-14 Corneal astigmatism; LIHC trans rs71327718 1 rs71327718 chr3:125592857 C/G cg07211511 chr3:129823064 LOC729375 -0.79 -8.23 -0.41 4e-15 Metabolite levels (HVA/5-HIAA ratio); LIHC cis rs1865760 0.566 rs2794720 chr6:26087202 G/C cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs7582180 0.614 rs4850931 chr2:101005145 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.07 0.4 1.17e-14 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg10802521 chr3:52805072 NEK4 -0.44 -7.22 -0.36 3.41e-12 Bipolar disorder; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.6 8.64 0.42 2.24e-16 Lymphocyte counts; LIHC cis rs9916302 0.904 rs7503069 chr17:37697128 C/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.13 -0.58 3.45e-32 Glomerular filtration rate (creatinine); LIHC cis rs112721625 1 rs112721625 chr17:57927426 AT/A cg02344993 chr17:57696989 CLTC 0.53 9.19 0.44 4e-18 Monocyte count; LIHC cis rs2066819 1.000 rs17118403 chr12:56630067 C/T cg26734620 chr12:56694298 CS 1.2 9.66 0.46 1.13e-19 Psoriasis vulgaris; LIHC cis rs1799949 0.536 rs4793227 chr17:41412250 A/C cg25072359 chr17:41440525 NA 0.37 5.82 0.3 1.35e-8 Menopause (age at onset); LIHC cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.83 -0.35 3.99e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4819052 1.000 rs2297286 chr21:46707897 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 10.73 0.5 2.43e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9640161 0.789 rs3735172 chr7:150028958 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 0.52 9.23 0.45 2.93e-18 Blood protein levels;Circulating chemerin levels; LIHC cis rs10779751 0.734 rs2039840 chr1:11125866 G/A cg08854313 chr1:11322531 MTOR 0.67 10.22 0.48 1.39e-21 Body mass index; LIHC cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg17971929 chr21:40555470 PSMG1 -0.47 -7.14 -0.36 5.78e-12 Cognitive function; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07278624 chr12:106696673 TCP11L2 0.45 6.09 0.31 3.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg23782820 chr8:58130467 NA 0.33 5.9 0.3 8.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg05590025 chr7:65112418 INTS4L2 0.62 6.79 0.34 4.9e-11 Diabetic kidney disease; LIHC cis rs941408 0.515 rs12610096 chr19:2778129 C/T cg06609049 chr19:2785107 THOP1 0.8 13.69 0.59 2.56e-34 Total cholesterol levels; LIHC cis rs4665809 1.000 rs6546766 chr2:26328680 T/C cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg15691649 chr6:25882328 NA -0.6 -7.75 -0.39 1.05e-13 Intelligence (multi-trait analysis); LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg02993280 chr1:107599747 PRMT6 0.65 10.58 0.5 8.35e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2153535 0.541 rs1414353 chr6:8485642 C/G cg21535247 chr6:8435926 SLC35B3 0.6 7.89 0.39 4.12e-14 Motion sickness; LIHC cis rs753778 0.570 rs10875465 chr8:142210500 A/G cg18755752 chr8:142205143 DENND3 -0.31 -5.77 -0.3 1.76e-8 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs4523957 0.748 rs12603592 chr17:2119818 A/T cg16513277 chr17:2031491 SMG6 -0.49 -7.34 -0.37 1.52e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs3808502 0.527 rs2736374 chr8:11113828 A/G cg03761569 chr8:649540 ERICH1 -0.48 -6.29 -0.32 9.74e-10 Neuroticism; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13707777 chr5:308627 AHRR;PDCD6 0.39 6.26 0.32 1.13e-9 Longevity; LIHC cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg05368731 chr17:41323189 NBR1 0.73 12.45 0.56 1.39e-29 Menopause (age at onset); LIHC cis rs6429082 0.623 rs7547849 chr1:235564254 G/A cg26050004 chr1:235667680 B3GALNT2 -0.69 -9.71 -0.46 7.59e-20 Adiposity; LIHC cis rs2153535 0.580 rs9406169 chr6:8509470 A/T cg23788917 chr6:8435910 SLC35B3 0.58 8.45 0.42 8.62e-16 Motion sickness; LIHC cis rs1499614 1.000 rs2707840 chr7:66158015 C/T cg12463550 chr7:65579703 CRCP 0.67 7.11 0.36 6.74e-12 Gout; LIHC cis rs921968 0.643 rs678218 chr2:219379709 C/A cg02985541 chr2:219472218 PLCD4 0.46 8.73 0.43 1.18e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs11583043 0.874 rs6577222 chr1:101420502 C/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.2 0.41 4.77e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs875971 0.830 rs6967708 chr7:65657313 A/T cg11764359 chr7:65958608 NA -0.84 -14.15 -0.61 4.2500000000000003e-36 Aortic root size; LIHC cis rs10924970 0.874 rs6681842 chr1:235332555 G/T cg26050004 chr1:235667680 B3GALNT2 0.4 5.79 0.3 1.55e-8 Asthma; LIHC cis rs4700695 0.686 rs251710 chr5:65347357 G/C cg21114390 chr5:65439923 SFRS12 0.45 5.89 0.3 9.42e-9 Facial morphology (factor 19); LIHC cis rs10751667 0.666 rs7395267 chr11:962326 C/A ch.11.42038R chr11:967971 AP2A2 0.56 10.16 0.48 2.2e-21 Alzheimer's disease (late onset); LIHC cis rs17253792 0.822 rs78826571 chr14:56048906 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs9911578 1.000 rs12947785 chr17:57045160 A/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.79 -0.43 7.66e-17 Intelligence (multi-trait analysis); LIHC cis rs9399135 0.967 rs9389251 chr6:135325717 A/G cg22676075 chr6:135203613 NA 0.38 6.17 0.32 1.88e-9 Red blood cell count; LIHC cis rs8060686 0.641 rs79375669 chr16:68099262 A/T cg09835421 chr16:68378352 PRMT7 -0.5 -5.9 -0.3 8.83e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs4474465 1.000 rs10899520 chr11:78183370 C/T cg02023728 chr11:77925099 USP35 0.34 6.03 0.31 4.14e-9 Alzheimer's disease (survival time); LIHC cis rs4888262 0.545 rs4588013 chr16:74703388 C/T cg01733217 chr16:74700730 RFWD3 0.81 16.06 0.66 1.24e-43 Testicular germ cell tumor; LIHC cis rs6430585 0.528 rs895285 chr2:136710554 A/G cg25344623 chr2:136566232 LCT -0.37 -5.91 -0.3 8.3e-9 Corneal structure; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15069758 chr1:110198731 GSTM4 0.44 6.1 0.31 2.82e-9 Lung function (FEV1/FVC); LIHC cis rs17685 0.753 rs4732595 chr7:75755139 A/G cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.9e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10193935 0.901 rs6733464 chr2:42563597 A/G cg27598129 chr2:42591480 NA -0.72 -11.59 -0.53 2.05e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs6951245 0.554 rs79367977 chr7:1152657 G/A cg22907277 chr7:1156413 C7orf50 0.81 7.69 0.38 1.63e-13 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1707322 1.000 rs11211244 chr1:46456673 G/A cg03146154 chr1:46216737 IPP 0.48 7.93 0.39 3.23e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs5769765 0.954 rs5770709 chr22:50245196 G/T cg26441486 chr22:50317300 CRELD2 -0.36 -6.5 -0.33 2.79e-10 Schizophrenia; LIHC cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg25897951 chr4:1244024 CTBP1;C4orf42 -0.42 -6.01 -0.31 4.68e-9 Longevity; LIHC cis rs3812111 0.609 rs549332 chr6:116454588 C/T cg08036074 chr6:116424633 NT5DC1 -0.46 -7.6 -0.38 2.92e-13 Age-related macular degeneration; LIHC cis rs7618501 0.519 rs3774749 chr3:50207227 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.49 -7.24 -0.36 3.04e-12 Intelligence (multi-trait analysis); LIHC cis rs7727544 0.735 rs272860 chr5:131684175 C/G cg07395648 chr5:131743802 NA -0.31 -6.41 -0.33 4.77e-10 Blood metabolite levels; LIHC cis rs9916302 0.800 rs8069451 chr17:37504933 C/T cg07936489 chr17:37558343 FBXL20 -0.81 -13.14 -0.58 3.24e-32 Glomerular filtration rate (creatinine); LIHC cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg24531977 chr5:56204891 C5orf35 -0.68 -9.73 -0.47 6.52e-20 Initial pursuit acceleration; LIHC cis rs734999 0.545 rs7368072 chr1:2556125 C/T cg18854424 chr1:2615690 NA 0.33 7.29 0.37 2.12e-12 Ulcerative colitis; LIHC cis rs861318 0.702 rs2793845 chr1:159032255 G/T cg11003133 chr1:159046391 AIM2 0.32 6.55 0.33 2.11e-10 Obesity-related traits; LIHC trans rs1005277 0.691 rs2474558 chr10:38486141 A/C cg17830980 chr10:43048298 ZNF37B 0.48 8.78 0.43 8.22e-17 Extrinsic epigenetic age acceleration; LIHC cis rs4908768 0.501 rs11121194 chr1:8569906 C/T cg20416874 chr1:8611966 RERE -0.68 -14.62 -0.62 6.36e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg06618935 chr21:46677482 NA -0.3 -5.76 -0.3 1.86e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg03806693 chr22:41940476 POLR3H 0.99 10.62 0.5 5.84e-23 Vitiligo; LIHC cis rs13108904 0.901 rs6851528 chr4:1296009 G/A cg00684032 chr4:1343700 KIAA1530 0.37 6.01 0.31 4.67e-9 Obesity-related traits; LIHC cis rs7903847 0.642 rs10882922 chr10:99158537 C/T cg08345082 chr10:99160200 RRP12 -0.4 -6.66 -0.34 1.12e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6456156 0.586 rs1358882 chr6:167467101 G/A cg07741184 chr6:167504864 NA 0.3 7.09 0.36 7.82e-12 Primary biliary cholangitis; LIHC cis rs8180040 0.726 rs61729713 chr3:47027192 A/G cg02527881 chr3:46936655 PTH1R 0.33 6.38 0.33 5.82e-10 Colorectal cancer; LIHC cis rs4665809 1.000 rs10182857 chr2:26344411 C/T cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs4663866 0.901 rs35390666 chr2:239193578 C/T cg16914508 chr2:239161102 PER2 0.83 5.97 0.31 5.94e-9 Irritable bowel syndrome; LIHC cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg18252515 chr7:66147081 NA -1.25 -16.45 -0.66 3.21e-45 Diabetic kidney disease; LIHC cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg10295955 chr4:187884368 NA -0.98 -22.22 -0.77 2.58e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs7412746 0.658 rs59024312 chr1:150909005 T/G cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs2066819 1.000 rs41392645 chr12:56696742 A/G cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs9399135 0.967 rs6923765 chr6:135335176 C/G cg24558204 chr6:135376177 HBS1L -0.38 -5.86 -0.3 1.08e-8 Red blood cell count; LIHC trans rs7980799 0.682 rs10844612 chr12:33603676 T/C cg26384229 chr12:38710491 ALG10B -0.45 -6.06 -0.31 3.52e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs875971 0.862 rs1167390 chr7:65575893 G/A cg18252515 chr7:66147081 NA 0.43 5.98 0.31 5.63e-9 Aortic root size; LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg12419862 chr22:24373484 LOC391322 -0.67 -9.9 -0.47 1.7e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs214034 0.505 rs12465611 chr2:17932833 G/T cg08383160 chr2:17981519 NA -0.31 -5.75 -0.3 1.95e-8 Response to amphetamines; LIHC cis rs12980942 0.630 rs11881940 chr19:41808432 A/T cg25627403 chr19:41769009 HNRNPUL1 0.57 6.95 0.35 1.88e-11 Coronary artery disease; LIHC cis rs7224685 0.608 rs17763551 chr17:3882309 C/T cg11204139 chr17:3907470 NA 0.48 5.73 0.3 2.25e-8 Type 2 diabetes; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.88e-16 Prudent dietary pattern; LIHC cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg11301795 chr4:187892539 NA -0.27 -7.03 -0.36 1.1e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.874 rs4900029 chr14:90686257 T/A cg04374321 chr14:90722782 PSMC1 0.71 13.51 0.59 1.23e-33 Mortality in heart failure; LIHC cis rs801193 1.000 rs2659915 chr7:66153101 A/G cg00343986 chr7:65444356 GUSB 0.4 6.11 0.31 2.75e-9 Aortic root size; LIHC cis rs739401 0.582 rs7932369 chr11:2958468 A/G cg20651018 chr11:3035856 CARS 0.34 5.75 0.3 1.95e-8 Longevity; LIHC cis rs116095464 0.614 rs62344339 chr5:252995 T/G cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs910316 0.934 rs7141705 chr14:75655352 G/C cg08847533 chr14:75593920 NEK9 -0.82 -17.1 -0.68 8.07e-48 Height; LIHC cis rs826838 0.967 rs73096706 chr12:38860563 G/A cg13010199 chr12:38710504 ALG10B 0.6 7.3 0.37 2.03e-12 Heart rate; LIHC cis rs1008375 0.931 rs2109519 chr4:17695453 A/G cg16339924 chr4:17578868 LAP3 0.44 5.72 0.3 2.38e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2153535 0.580 rs9505458 chr6:8479215 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs9549328 0.879 rs12428058 chr13:113636504 G/A cg08528486 chr13:113648767 MCF2L -0.39 -6.38 -0.33 5.89e-10 Systolic blood pressure; LIHC cis rs11758351 1.000 rs79868973 chr6:26189312 C/G cg16070018 chr6:26224392 HIST1H3E 0.58 6.82 0.35 4.1e-11 Gout;Renal underexcretion gout; LIHC cis rs17376456 0.877 rs66696214 chr5:93424533 G/A cg25358565 chr5:93447407 FAM172A 1.14 10.48 0.49 1.87e-22 Diabetic retinopathy; LIHC cis rs13217239 0.646 rs35691005 chr6:26972070 A/G cg18867708 chr6:26865862 GUSBL1 0.52 8.1 0.4 9.8e-15 Schizophrenia; LIHC cis rs4478037 0.731 rs9835090 chr3:33107671 G/T cg16652328 chr3:33138982 GLB1;TMPPE -0.56 -6.75 -0.34 6.37e-11 Major depressive disorder; LIHC cis rs3796352 1.000 rs11713859 chr3:53042080 C/A cg07884673 chr3:53033167 SFMBT1 0.92 6.74 0.34 6.85e-11 Immune reponse to smallpox (secreted IL-2); LIHC cis rs875971 0.862 rs7783779 chr7:65796626 A/G cg18252515 chr7:66147081 NA 0.47 6.89 0.35 2.67e-11 Aortic root size; LIHC cis rs10751667 0.643 rs6597970 chr11:928669 C/A ch.11.42038R chr11:967971 AP2A2 0.53 9.44 0.45 5.92e-19 Alzheimer's disease (late onset); LIHC trans rs6934970 1.000 rs7763826 chr6:113070133 A/G cg20627988 chr10:133946881 JAKMIP3 0.45 6.23 0.32 1.35e-9 Bipolar disorder (body mass index interaction); LIHC cis rs34779708 0.832 rs6481946 chr10:35529114 A/G cg03585969 chr10:35415529 CREM 0.78 11.33 0.52 1.82e-25 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2180341 0.855 rs4308584 chr6:127714874 A/G cg27446573 chr6:127587934 RNF146 0.82 13.32 0.58 6.69e-33 Breast cancer; LIHC cis rs6960043 0.905 rs10264723 chr7:15054370 T/C cg19272540 chr7:15055459 NA 0.26 7.03 0.36 1.12e-11 Type 2 diabetes; LIHC cis rs1475718 0.526 rs7854734 chr9:137122410 C/G cg21243944 chr9:137118148 NA 0.42 6.11 0.31 2.75e-9 Immature fraction of reticulocytes;Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg20887711 chr4:1340912 KIAA1530 -0.71 -10.79 -0.5 1.51e-23 Obesity-related traits; LIHC cis rs11122272 0.735 rs2790889 chr1:231520240 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.64 -0.5 5.08e-23 Hemoglobin concentration; LIHC cis rs9457247 1.000 rs364283 chr6:167383750 C/T cg23791538 chr6:167370224 RNASET2 -0.67 -11.63 -0.53 1.44e-26 Crohn's disease; LIHC cis rs7927592 0.913 rs6591344 chr11:68360873 G/A cg16797656 chr11:68205561 LRP5 0.5 7.8 0.39 7.44e-14 Total body bone mineral density; LIHC cis rs8180040 0.654 rs4682831 chr3:47027138 A/G cg16586182 chr3:47516702 SCAP 0.44 7.71 0.38 1.41e-13 Colorectal cancer; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg10755058 chr3:40428713 ENTPD3 0.39 6.64 0.34 1.22e-10 Renal cell carcinoma; LIHC cis rs35306767 0.807 rs34982663 chr10:852521 C/G cg20503657 chr10:835505 NA 1.32 13.18 0.58 2.41e-32 Eosinophil percentage of granulocytes; LIHC cis rs986417 1.000 rs1254318 chr14:60902549 T/C cg27398547 chr14:60952738 C14orf39 -0.76 -8.61 -0.42 2.66e-16 Gut microbiota (bacterial taxa); LIHC cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg02564969 chr6:151773285 C6orf211;RMND1 0.4 5.81 0.3 1.44e-8 Menarche (age at onset); LIHC cis rs3762637 1.000 rs9867429 chr3:122232668 T/C cg24169773 chr3:122142474 KPNA1 -0.47 -9.13 -0.44 6.09e-18 LDL cholesterol levels; LIHC cis rs875971 0.830 rs778715 chr7:65849209 C/T cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg23262073 chr20:60523788 NA -0.3 -6.22 -0.32 1.43e-9 Body mass index; LIHC cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg00484396 chr16:3507460 NAT15 0.43 7.3 0.37 2e-12 Tuberculosis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg05082095 chr1:155099843 EFNA1 -0.51 -6.47 -0.33 3.31e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs573688 0.630 rs653699 chr1:71434501 G/A cg07200748 chr10:111767864 ADD3 -1.03 -6.26 -0.32 1.16e-9 Intelligence (multi-trait analysis); LIHC cis rs2204008 0.807 rs4123933 chr12:37973539 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.67 0.46 1.04e-19 Height; LIHC cis rs11758351 1.000 rs16891405 chr6:26204506 A/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.33 0.37 1.72e-12 Gout;Renal underexcretion gout; LIHC cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg05025164 chr4:1340916 KIAA1530 -0.4 -6.02 -0.31 4.56e-9 Obesity-related traits; LIHC cis rs17376456 0.504 rs6898507 chr5:93082343 C/T cg25358565 chr5:93447407 FAM172A 0.8 7.68 0.38 1.63e-13 Diabetic retinopathy; LIHC cis rs72781680 1.000 rs115861480 chr2:24129464 T/A cg08917208 chr2:24149416 ATAD2B 0.93 8.0 0.4 1.96e-14 Lymphocyte counts; LIHC cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg02931644 chr1:25747376 RHCE 0.38 8.44 0.42 9.21e-16 Erythrocyte sedimentation rate; LIHC cis rs7953249 1.000 rs7953249 chr12:121403724 A/G cg02403541 chr12:121454288 C12orf43 0.35 6.1 0.31 2.9e-9 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs10779751 0.960 rs12739368 chr1:11288247 T/C cg08854313 chr1:11322531 MTOR 0.81 11.45 0.53 6.22e-26 Body mass index; LIHC cis rs3736594 0.643 rs2384655 chr2:27952235 A/T cg27432699 chr2:27873401 GPN1 -0.45 -7.06 -0.36 9.09e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs743757 1.000 rs1107265 chr3:50431995 A/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.64 0.38 2.23e-13 Diastolic blood pressure; LIHC cis rs12701220 0.894 rs34712249 chr7:1036634 C/T cg26769984 chr7:1090371 C7orf50 0.61 7.75 0.39 1.03e-13 Bronchopulmonary dysplasia; LIHC cis rs7116495 0.609 rs577435 chr11:71794681 C/T cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.07e-17 Severe influenza A (H1N1) infection; LIHC cis rs826838 0.967 rs11183022 chr12:38652519 G/A cg13010199 chr12:38710504 ALG10B 0.64 7.58 0.38 3.2e-13 Heart rate; LIHC cis rs709400 1.000 rs8018979 chr14:104109087 G/A cg26031613 chr14:104095156 KLC1 1.05 14.18 0.61 3.09e-36 Body mass index; LIHC cis rs4953318 0.619 rs12105417 chr2:46361255 A/C cg12428440 chr2:46370979 PRKCE 0.46 6.33 0.32 7.73e-10 Red blood cell count;Hematocrit;Red blood cell traits; LIHC cis rs9309473 0.607 rs2421489 chr2:73593448 A/G cg20560298 chr2:73613845 ALMS1 -0.42 -6.68 -0.34 9.92e-11 Metabolite levels; LIHC trans rs7714584 1.000 rs11749391 chr5:150229066 T/C cg20675040 chr8:143813288 C8orf55 0.34 6.13 0.31 2.41e-9 Crohn's disease; LIHC cis rs11864453 0.713 rs12708926 chr16:72126063 T/C cg16558253 chr16:72132732 DHX38 -0.51 -8.1 -0.4 9.86e-15 Fibrinogen levels; LIHC cis rs7831492 0.564 rs11787479 chr8:41613496 A/G cg17182837 chr8:41585554 ANK1 -0.25 -6.1 -0.31 2.95e-9 Colorectal cancer; LIHC cis rs4755351 0.553 rs11032157 chr11:33158566 A/G cg05567920 chr11:33183001 CSTF3 0.43 6.24 0.32 1.28e-9 Lung cancer in ever smokers; LIHC cis rs6570726 0.791 rs952406 chr6:145925616 C/A cg23711669 chr6:146136114 FBXO30 0.67 11.56 0.53 2.5e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs919433 0.783 rs3097383 chr2:198236887 A/G cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.8e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6061231 0.798 rs2427308 chr20:60969451 C/T cg03945807 chr20:60948434 NA 0.4 5.79 0.3 1.56e-8 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02737830 chr12:64616354 C12orf66 0.5 7.71 0.38 1.36e-13 Pancreatic cancer; LIHC cis rs600806 0.778 rs1525916 chr1:110010949 A/G cg08911820 chr1:110026001 ATXN7L2 -0.55 -6.81 -0.35 4.43e-11 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg11766577 chr21:47581405 C21orf56 -0.43 -7.07 -0.36 8.72e-12 Testicular germ cell tumor; LIHC cis rs11105298 0.891 rs10777185 chr12:89921275 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.3 -0.37 2.09e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs7582180 0.715 rs920270 chr2:100917961 T/C cg14675211 chr2:100938903 LONRF2 0.54 8.08 0.4 1.11e-14 Intelligence (multi-trait analysis); LIHC cis rs10089 0.953 rs2016015 chr5:127527253 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.24 0.32 1.31e-9 Ileal carcinoids; LIHC cis rs7833790 0.700 rs28390260 chr8:82769175 A/T cg17211192 chr8:82754475 SNX16 0.57 10.37 0.49 4.33e-22 Diastolic blood pressure; LIHC cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg06481639 chr22:41940642 POLR3H 0.61 5.89 0.3 9.45e-9 Vitiligo; LIHC cis rs7493 0.755 rs13223537 chr7:94966167 C/T cg21856205 chr7:94953877 PON1 0.49 6.05 0.31 3.77e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs716804 0.504 rs11042725 chr11:10325325 C/A cg01453529 chr11:10209919 SBF2 -0.3 -5.75 -0.3 1.96e-8 Neuroticism; LIHC cis rs1866706 0.896 rs7940022 chr11:12873906 G/T cg25843174 chr11:12811716 TEAD1 -0.31 -6.61 -0.34 1.48e-10 Intelligence (multi-trait analysis); LIHC cis rs9427116 0.502 rs7531982 chr1:154596122 A/T cg17218026 chr1:154582156 ADAR 0.35 6.81 0.35 4.43e-11 Blood protein levels; LIHC cis rs1198430 0.562 rs504145 chr1:23788310 C/T cg13183780 chr1:23809682 ASAP3 -0.37 -6.69 -0.34 9.05e-11 Total cholesterol levels; LIHC cis rs7520050 0.751 rs2991975 chr1:46024526 A/G cg24296786 chr1:45957014 TESK2 0.42 5.88 0.3 9.78e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6977660 0.714 rs10270468 chr7:19810559 T/C cg07541023 chr7:19748670 TWISTNB 0.39 5.76 0.3 1.83e-8 Thyroid stimulating hormone; LIHC cis rs11098499 0.865 rs28753180 chr4:120405367 A/T cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.65e-29 Corneal astigmatism; LIHC cis rs2412488 0.778 rs10032903 chr4:54355023 G/T cg22241045 chr4:54363911 LNX1 0.41 6.7 0.34 8.67e-11 DNA methylation (variation); LIHC trans rs2235573 0.527 rs139885 chr22:38371039 C/T cg19894588 chr14:64061835 NA 0.48 6.35 0.32 6.78e-10 Glioblastoma;Glioma; LIHC cis rs7208859 0.623 rs28556733 chr17:29083945 T/G cg13385521 chr17:29058706 SUZ12P 0.83 8.21 0.41 4.55e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs986417 0.818 rs10133871 chr14:61063771 A/C cg27398547 chr14:60952738 C14orf39 0.49 5.88 0.3 9.67e-9 Gut microbiota (bacterial taxa); LIHC cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg18357526 chr6:26021779 HIST1H4A 0.89 12.44 0.56 1.49e-29 Intelligence (multi-trait analysis); LIHC cis rs477692 1.000 rs513736 chr10:131406489 C/T cg05714579 chr10:131428358 MGMT 0.45 7.49 0.38 5.98e-13 Response to temozolomide; LIHC trans rs7613875 0.600 rs7061 chr3:50114515 C/T cg21659725 chr3:3221576 CRBN -0.54 -8.1 -0.4 9.57e-15 Body mass index; LIHC cis rs921968 0.541 rs3755041 chr2:219442499 A/T cg02176678 chr2:219576539 TTLL4 -0.55 -7.58 -0.38 3.38e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7617480 0.648 rs4974088 chr3:48898749 T/C cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.28 0.32 1.03e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9640161 0.702 rs3735175 chr7:150020457 C/T cg10018233 chr7:150070692 REPIN1 0.56 9.41 0.45 7.31e-19 Blood protein levels;Circulating chemerin levels; LIHC cis rs116095464 0.558 rs55838121 chr5:266890 G/A cg22857025 chr5:266934 NA -1.5 -18.04 -0.7 1.31e-51 Breast cancer; LIHC cis rs1062177 0.756 rs2915815 chr5:151115883 G/C cg00977110 chr5:151150581 G3BP1 -0.57 -7.18 -0.36 4.48e-12 Preschool internalizing problems; LIHC cis rs7520050 0.966 rs785471 chr1:46518677 T/C cg03146154 chr1:46216737 IPP -0.36 -6.02 -0.31 4.53e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4423214 0.959 rs12793224 chr11:71168710 G/A cg05163923 chr11:71159392 DHCR7 0.89 13.63 0.59 4.49e-34 Vitamin D levels; LIHC cis rs6466055 0.932 rs2057884 chr7:104930250 T/C cg04380332 chr7:105027541 SRPK2 0.31 6.14 0.32 2.27e-9 Schizophrenia; LIHC cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg03452623 chr4:187889614 NA -0.33 -8.31 -0.41 2.3e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs561341 0.689 rs578635 chr17:30289897 A/C cg20587970 chr11:113659929 NA -0.43 -6.15 -0.32 2.1e-9 Hip circumference adjusted for BMI; LIHC cis rs1789 0.786 rs6414768 chr4:15695363 A/G cg24225360 chr4:15471699 CC2D2A -0.39 -6.05 -0.31 3.87e-9 Blood protein levels; LIHC cis rs34172651 0.517 rs2303084 chr16:24834581 G/C cg04756594 chr16:24857601 SLC5A11 0.62 8.77 0.43 8.81e-17 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg06634786 chr22:41940651 POLR3H 0.74 7.67 0.38 1.78e-13 Vitiligo; LIHC cis rs1865721 0.771 rs7231277 chr18:73136724 A/G cg26385618 chr18:73139727 C18orf62 -0.32 -8.71 -0.43 1.35e-16 Intelligence; LIHC cis rs1190552 0.802 rs10148411 chr14:102883531 A/G cg10241871 chr14:102965420 TECPR2 -0.39 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs6543140 0.964 rs6748390 chr2:103062175 A/G cg09003973 chr2:102972529 NA 0.52 5.78 0.3 1.73e-8 Blood protein levels; LIHC cis rs9816226 0.591 rs77805826 chr3:185798025 C/T cg00760338 chr3:185826511 ETV5 -0.71 -5.81 -0.3 1.41e-8 Obesity;Body mass index; LIHC cis rs12497850 0.931 rs9876848 chr3:48844059 G/A cg07636037 chr3:49044803 WDR6 0.92 16.44 0.66 3.63e-45 Parkinson's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24594830 chr12:77459352 E2F7 0.46 6.29 0.32 9.93e-10 Lung function (FEV1/FVC); LIHC cis rs798554 0.757 rs1182187 chr7:2870454 T/G cg13628971 chr7:2884303 GNA12 0.51 7.02 0.36 1.17e-11 Height; LIHC trans rs1945213 0.694 rs7122627 chr11:55862565 A/G cg03929089 chr4:120376271 NA 0.53 6.87 0.35 3.01e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs921968 0.643 rs3932856 chr2:219320207 C/A cg17980119 chr2:219472607 PLCD4 0.35 6.1 0.31 2.82e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs11971779 1.000 rs75919582 chr7:139054919 G/A cg07862535 chr7:139043722 LUC7L2 0.74 10.77 0.5 1.7e-23 Diisocyanate-induced asthma; LIHC cis rs6582630 0.519 rs11514372 chr12:38308613 T/G cg26384229 chr12:38710491 ALG10B 0.6 8.16 0.4 6.58e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs9640161 0.783 rs35435439 chr7:150063534 C/T cg17279839 chr7:150038598 RARRES2 0.4 7.87 0.39 4.62e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs11690935 0.921 rs3770445 chr2:172708919 T/C cg13550731 chr2:172543902 DYNC1I2 -0.92 -17.25 -0.68 2.01e-48 Schizophrenia; LIHC cis rs9381040 0.655 rs9381031 chr6:41044957 A/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.22 -0.32 1.44e-9 Alzheimer's disease (late onset); LIHC cis rs11583043 0.918 rs6577216 chr1:101409972 C/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.61 8.46 0.42 7.79e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs5770917 1.000 rs1557503 chr22:51013072 G/A cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.48 -5.97 -0.31 5.88e-9 Narcolepsy; LIHC cis rs1401999 1.000 rs6767013 chr3:183680102 G/A cg05044414 chr3:183734942 ABCC5 0.34 5.98 0.31 5.62e-9 Anterior chamber depth; LIHC cis rs35110281 0.715 rs2838353 chr21:45119228 C/T cg04455712 chr21:45112962 RRP1B 0.46 8.18 0.4 5.71e-15 Mean corpuscular volume; LIHC cis rs9399135 0.967 rs4895439 chr6:135318854 A/T cg22676075 chr6:135203613 NA 0.39 6.38 0.33 5.82e-10 Red blood cell count; LIHC cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg07092213 chr7:1199455 ZFAND2A -0.41 -6.07 -0.31 3.38e-9 Longevity;Endometriosis; LIHC cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.85 8.09 0.4 1.02e-14 Platelet count; LIHC cis rs11031096 0.727 rs7932702 chr11:4124372 C/T cg18678763 chr11:4115507 RRM1 -0.54 -8.06 -0.4 1.28e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1580019 0.539 rs11769109 chr7:32571352 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.61 8.98 0.44 1.9e-17 Cognitive ability; LIHC cis rs35306767 0.812 rs1013504 chr10:952816 T/C cg20503657 chr10:835505 NA 1.38 12.83 0.57 5.02e-31 Eosinophil percentage of granulocytes; LIHC cis rs708547 0.836 rs1277287 chr4:57853147 C/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.63 8.18 0.4 5.62e-15 Response to bleomycin (chromatid breaks); LIHC cis rs7757419 0.887 rs9296115 chr6:34434715 A/C cg17518776 chr6:34434842 PACSIN1 -0.3 -6.12 -0.31 2.62e-9 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals; LIHC cis rs34172651 0.571 rs9922156 chr16:24704329 C/A cg04756594 chr16:24857601 SLC5A11 -0.39 -6.48 -0.33 3.2e-10 Intelligence (multi-trait analysis); LIHC cis rs4423214 0.610 rs12793607 chr11:71129316 C/T cg05163923 chr11:71159392 DHCR7 -0.75 -11.67 -0.53 1.01e-26 Vitamin D levels; LIHC cis rs2404602 0.735 rs2454454 chr15:76823647 A/G cg03037974 chr15:76606532 NA -0.59 -10.25 -0.48 1.17e-21 Blood metabolite levels; LIHC cis rs11233413 0.794 rs66653310 chr11:82717000 A/T cg24227371 chr11:82718527 RAB30 -0.34 -7.45 -0.37 7.94e-13 Economic and political preferences (feminism/equality); LIHC trans rs7615952 0.688 rs4422259 chr3:125545831 C/T cg07211511 chr3:129823064 LOC729375 -0.52 -8.08 -0.4 1.13e-14 Blood pressure (smoking interaction); LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg06873352 chr17:61820015 STRADA 0.74 13.45 0.59 2.07e-33 Prudent dietary pattern; LIHC cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg00343986 chr7:65444356 GUSB -0.43 -6.11 -0.31 2.75e-9 Aortic root size; LIHC cis rs4927850 0.794 rs4927849 chr3:195738482 A/G cg00031303 chr3:195681400 NA 0.59 7.0 0.35 1.33e-11 Pancreatic cancer; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg24807761 chr7:134632531 CALD1 0.47 6.26 0.32 1.18e-9 Hip circumference; LIHC cis rs9326248 0.581 rs7120515 chr11:116991926 A/G cg01368799 chr11:117014884 PAFAH1B2 0.64 9.81 0.47 3.65e-20 Blood protein levels; LIHC cis rs1552244 0.882 rs55962400 chr3:10044457 C/T cg08888203 chr3:10149979 C3orf24 0.49 6.12 0.31 2.62e-9 Alzheimer's disease; LIHC cis rs11048434 0.736 rs11048337 chr12:9121330 C/A cg04155231 chr12:9217510 LOC144571 0.31 5.95 0.31 6.68e-9 Sjögren's syndrome; LIHC cis rs4906332 0.840 rs34161327 chr14:103857325 G/A cg19000871 chr14:103996768 TRMT61A -0.44 -7.53 -0.38 4.54e-13 Coronary artery disease; LIHC cis rs61990749 0.511 rs724263 chr14:78321874 G/T cg23188588 chr14:78226832 SNW1;C14orf178 0.49 7.76 0.39 1e-13 Fibroblast growth factor basic levels; LIHC cis rs2559856 1.000 rs2695299 chr12:102082664 G/A cg12924262 chr12:102091054 CHPT1 0.5 7.99 0.4 2.04e-14 Blood protein levels; LIHC cis rs8077889 0.917 rs4793038 chr17:41916761 A/T cg26893861 chr17:41843967 DUSP3 0.92 10.76 0.5 1.96e-23 Triglycerides; LIHC cis rs68170813 0.559 rs79543528 chr7:106891090 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.97 -0.31 5.87e-9 Coronary artery disease; LIHC cis rs2444217 0.872 rs2531977 chr16:4043701 C/G cg09300795 chr16:4042428 ADCY9 0.57 10.17 0.48 2.1e-21 Body mass index; LIHC cis rs62458065 1.000 rs6462364 chr7:32464776 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.64 -7.32 -0.37 1.77e-12 Metabolite levels (HVA/MHPG ratio); LIHC cis rs910316 0.503 rs12894709 chr14:75441734 G/A cg08847533 chr14:75593920 NEK9 0.86 17.23 0.68 2.51e-48 Height; LIHC trans rs10411161 0.630 rs7252101 chr19:52359372 A/C cg22319618 chr22:45562946 NUP50 -0.52 -6.48 -0.33 3.11e-10 Breast cancer; LIHC cis rs8060686 0.516 rs1971546 chr16:68280893 T/C cg09835421 chr16:68378352 PRMT7 -0.47 -5.76 -0.3 1.86e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs9309473 1.000 rs10190219 chr2:73658331 C/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.68 -0.34 9.86e-11 Metabolite levels; LIHC cis rs875971 1.000 rs7789554 chr7:65946038 A/G cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg15691649 chr6:25882328 NA 0.78 10.7 0.5 3.16e-23 Blood metabolite levels; LIHC cis rs17125944 0.686 rs11157933 chr14:53349798 G/A cg00686598 chr14:53173677 PSMC6 -0.76 -8.58 -0.42 3.28e-16 Alzheimer's disease (late onset); LIHC cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg18402987 chr7:1209562 NA 0.81 5.98 0.31 5.62e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs34779708 0.966 rs12769575 chr10:35435927 A/T cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4853036 0.951 rs10185266 chr2:70152407 C/G cg02498382 chr2:70120550 SNRNP27 -0.42 -6.75 -0.34 6.19e-11 Colorectal or endometrial cancer; LIHC cis rs2455799 0.613 rs4685260 chr3:15832417 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.48 -0.37 6.36e-13 Mean platelet volume; LIHC cis rs7615952 0.599 rs7631268 chr3:125755664 T/A cg05084668 chr3:125655381 ALG1L -0.41 -6.35 -0.32 6.66e-10 Blood pressure (smoking interaction); LIHC cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg06481639 chr22:41940642 POLR3H 0.72 7.09 0.36 7.94e-12 Vitiligo; LIHC cis rs6840360 0.593 rs6855883 chr4:152688997 A/G cg22705602 chr4:152727874 NA -0.4 -8.47 -0.42 7.54e-16 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13369624 chr13:21714458 SAP18 0.41 6.41 0.33 4.95e-10 Cognitive function; LIHC cis rs782590 0.643 rs13009906 chr2:55739434 A/G cg18811423 chr2:55921094 PNPT1 -0.53 -7.94 -0.39 2.95e-14 Metabolic syndrome; LIHC cis rs9399135 0.967 rs4895434 chr6:135293365 G/A cg24558204 chr6:135376177 HBS1L 0.39 6.46 0.33 3.51e-10 Red blood cell count; LIHC cis rs240764 0.658 rs10457849 chr6:101245591 A/G cg09795085 chr6:101329169 ASCC3 0.56 7.79 0.39 8.05e-14 Neuroticism; LIHC cis rs9473924 0.542 rs9463665 chr6:50928520 G/T cg14470998 chr6:50812995 TFAP2B 0.82 7.47 0.37 6.75e-13 Body mass index; LIHC cis rs2933343 1.000 rs1683778 chr3:128644595 A/G cg25356066 chr3:128598488 ACAD9 0.53 6.97 0.35 1.64e-11 IgG glycosylation; LIHC cis rs751728 1.000 rs2296748 chr6:33745071 C/T cg25922239 chr6:33757077 LEMD2 0.45 7.57 0.38 3.56e-13 Crohn's disease; LIHC cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg18357526 chr6:26021779 HIST1H4A -0.56 -7.55 -0.38 3.91e-13 Blood metabolite levels; LIHC cis rs6714710 0.603 rs1875699 chr2:98580724 G/T cg26665480 chr2:98280029 ACTR1B 0.43 5.98 0.31 5.55e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs1005277 0.579 rs1621040 chr10:38497232 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.1 -0.44 7.43e-18 Extrinsic epigenetic age acceleration; LIHC cis rs262150 0.851 rs2527224 chr7:158769198 G/A cg27247782 chr7:158767135 NA -0.3 -6.07 -0.31 3.43e-9 Facial morphology (factor 20); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14298269 chr14:102689372 WDR20 0.43 6.46 0.33 3.65e-10 Longevity; LIHC cis rs7408868 1.000 rs7247906 chr19:15271135 T/G cg02272795 chr19:15279244 NOTCH3 -0.32 -5.82 -0.3 1.35e-8 Pulse pressure; LIHC trans rs9818758 0.607 rs11713297 chr3:49213030 A/G cg21046355 chr19:52772717 ZNF766 -0.5 -6.41 -0.33 4.79e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2204008 0.521 rs7311188 chr12:38542813 C/G cg26384229 chr12:38710491 ALG10B -0.48 -6.76 -0.34 6.1e-11 Bladder cancer; LIHC cis rs7666738 0.609 rs28833816 chr4:98868866 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.89 0.35 2.77e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs801193 0.660 rs1962050 chr7:66240008 C/T cg18252515 chr7:66147081 NA 0.42 6.1 0.31 2.92e-9 Aortic root size; LIHC cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg02290350 chr8:58132656 NA 0.5 10.64 0.5 5.15e-23 Developmental language disorder (linguistic errors); LIHC cis rs2933343 0.672 rs1872545 chr3:128645039 G/C cg25356066 chr3:128598488 ACAD9 0.52 7.25 0.37 2.74e-12 IgG glycosylation; LIHC cis rs4713118 0.513 rs149897 chr6:28006650 A/G cg23485639 chr6:28045615 ZNF165 0.38 5.87 0.3 1.02e-8 Parkinson's disease; LIHC cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 9.19 0.45 3.83e-18 Platelet count; LIHC cis rs2204008 0.687 rs1733404 chr12:38123395 G/T cg26384229 chr12:38710491 ALG10B -0.82 -10.55 -0.5 1.02e-22 Bladder cancer; LIHC trans rs6489882 0.671 rs4767025 chr12:113358794 C/T cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs637571 0.522 rs550435 chr11:65732651 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.11 0.44 7.19e-18 Eosinophil percentage of white cells; LIHC cis rs921968 0.510 rs620887 chr2:219465594 C/A cg02985541 chr2:219472218 PLCD4 0.41 6.71 0.34 8.11e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs651907 0.557 rs12629658 chr3:101356535 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.08 -0.31 3.29e-9 Colorectal cancer; LIHC cis rs2257205 0.667 rs6503884 chr17:56940026 G/A cg12560992 chr17:57184187 TRIM37 0.67 7.28 0.37 2.36e-12 Pancreatic cancer; LIHC trans rs17685 0.753 rs1574107 chr7:75685047 A/C cg19862616 chr7:65841803 NCRNA00174 0.92 19.13 0.72 5.44e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1577917 0.958 rs6921315 chr6:86471668 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.32 -5.72 -0.3 2.34e-8 Response to antipsychotic treatment; LIHC cis rs6060717 0.610 rs6058393 chr20:34608664 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -8.03 -0.4 1.56e-14 Hip circumference adjusted for BMI; LIHC cis rs4975616 0.869 rs452932 chr5:1330253 T/C cg26373071 chr5:1325741 CLPTM1L 0.35 5.73 0.3 2.25e-8 Lung cancer; LIHC trans rs6952808 0.692 rs10950473 chr7:1999453 G/A cg04565464 chr8:145669602 NFKBIL2 0.43 7.08 0.36 8.02e-12 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg00343986 chr7:65444356 GUSB -0.44 -6.21 -0.32 1.54e-9 Aortic root size; LIHC cis rs7208859 0.673 rs216435 chr17:28922737 G/T cg13385521 chr17:29058706 SUZ12P 0.58 5.82 0.3 1.38e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2075371 0.933 rs1901214 chr7:133945108 C/T cg11752832 chr7:134001865 SLC35B4 -0.51 -7.73 -0.39 1.24e-13 Mean platelet volume; LIHC cis rs6545883 0.894 rs4672436 chr2:61603357 A/C cg15711740 chr2:61764176 XPO1 0.42 5.74 0.3 2.14e-8 Tuberculosis; LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg00280220 chr17:61926910 NA 0.4 6.3 0.32 9.18e-10 Prudent dietary pattern; LIHC cis rs10751667 0.643 rs10751669 chr11:942344 C/G cg10932868 chr11:921992 NA -0.38 -7.21 -0.36 3.51e-12 Alzheimer's disease (late onset); LIHC cis rs7582720 1.000 rs114702158 chr2:203821793 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4800452 0.826 rs9949705 chr18:20745345 A/G cg26136497 chr18:20735537 CABLES1 -0.46 -5.83 -0.3 1.29e-8 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg02290350 chr8:58132656 NA 0.45 8.97 0.44 2.05e-17 Developmental language disorder (linguistic errors); LIHC cis rs10751667 0.666 rs10902247 chr11:953686 G/A cg06064525 chr11:970664 AP2A2 -0.56 -15.03 -0.63 1.52e-39 Alzheimer's disease (late onset); LIHC cis rs801193 0.967 rs2707849 chr7:66152712 T/C cg14393609 chr7:65229607 NA 0.38 5.87 0.3 1.02e-8 Aortic root size; LIHC cis rs7917772 0.503 rs11191347 chr10:104351617 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.75 0.57 9.63e-31 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9534288 0.659 rs2146882 chr13:46668111 A/G cg15192986 chr13:46630673 CPB2 -0.43 -6.09 -0.31 3.06e-9 Blood protein levels; LIHC cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg18654377 chr3:49208889 KLHDC8B -0.49 -5.9 -0.3 8.63e-9 Menarche (age at onset); LIHC cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg18404041 chr3:52824283 ITIH1 -0.47 -7.79 -0.39 8.08e-14 Electroencephalogram traits; LIHC cis rs11785400 0.793 rs11543967 chr8:143739435 A/G cg10596483 chr8:143751796 JRK -0.49 -7.59 -0.38 2.97e-13 Schizophrenia; LIHC cis rs6545883 0.929 rs10193666 chr2:61629408 C/T cg14146966 chr2:61757674 XPO1 -0.44 -7.53 -0.38 4.6e-13 Tuberculosis; LIHC cis rs568617 0.716 rs17854357 chr11:65601560 G/C cg04055107 chr11:65626734 MUS81;CFL1 0.58 5.87 0.3 1.06e-8 Crohn's disease; LIHC cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg18230493 chr5:56204884 C5orf35 0.46 6.19 0.32 1.72e-9 Initial pursuit acceleration; LIHC trans rs916888 0.687 rs199456 chr17:44797919 C/T cg12297030 chr17:43662878 NA -0.63 -6.09 -0.31 3.08e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7914558 0.646 rs1046778 chr10:104661484 T/C cg15744005 chr10:104629667 AS3MT -0.34 -7.16 -0.36 5.12e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg09323728 chr8:95962352 TP53INP1 -0.35 -7.75 -0.39 1.06e-13 Type 2 diabetes; LIHC cis rs611744 0.517 rs62537573 chr8:109269281 C/T cg21045802 chr8:109455806 TTC35 0.63 11.29 0.52 2.52e-25 Dupuytren's disease; LIHC cis rs7249142 0.549 rs2239369 chr19:19292405 A/T cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B 0.4 6.74 0.34 6.85e-11 IgG glycosylation; LIHC cis rs2303759 0.918 rs8107548 chr19:49870643 T/C cg24324837 chr19:49891574 CCDC155 0.38 6.09 0.31 2.99e-9 Multiple sclerosis; LIHC cis rs6976053 0.541 rs314359 chr7:100411278 T/C cg03098644 chr7:100410630 EPHB4 -0.42 -6.78 -0.34 5.28e-11 Plasminogen activator inhibitor type 1 levels (PAI-1); LIHC cis rs9303280 0.685 rs9916765 chr17:38005595 T/C cg11212589 chr17:38028394 ZPBP2 0.35 7.28 0.37 2.33e-12 Self-reported allergy; LIHC cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg18876405 chr7:65276391 NA 0.56 9.4 0.45 7.78e-19 Calcium levels; LIHC cis rs738322 0.533 rs5756934 chr22:38547279 G/A cg25457927 chr22:38595422 NA -0.4 -9.83 -0.47 3.12e-20 Cutaneous nevi; LIHC cis rs11098699 1.000 rs931707 chr4:124202535 G/A cg09941581 chr4:124220074 SPATA5 0.3 5.74 0.3 2.1e-8 Mosquito bite size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16682046 chr11:82612617 PRCP;C11orf82 0.43 6.46 0.33 3.5e-10 Cognitive function; LIHC cis rs12220238 0.818 rs16931294 chr10:75999169 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.75 8.51 0.42 5.41e-16 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9858542 0.953 rs11715915 chr3:49455330 A/G cg03060546 chr3:49711283 APEH 0.48 6.94 0.35 2.01e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs9818758 0.607 rs35108630 chr3:49088356 T/A cg06212747 chr3:49208901 KLHDC8B -0.69 -5.91 -0.3 8.11e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs10411161 0.702 rs16983200 chr19:52386723 G/A cg22319618 chr22:45562946 NUP50 -0.61 -8.42 -0.41 1.06e-15 Breast cancer; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs875971 0.862 rs11760844 chr7:65739883 C/G cg18252515 chr7:66147081 NA 0.45 6.37 0.33 6.18e-10 Aortic root size; LIHC cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg06640241 chr16:89574553 SPG7 0.82 14.92 0.63 3.85e-39 Multiple myeloma (IgH translocation); LIHC cis rs4759375 0.748 rs596940 chr12:123560731 T/C cg00376283 chr12:123451042 ABCB9 -0.55 -5.84 -0.3 1.23e-8 HDL cholesterol; LIHC cis rs12893668 0.572 rs4906350 chr14:104111794 C/T cg08213375 chr14:104286397 PPP1R13B 0.36 5.81 0.3 1.4e-8 Reticulocyte count; LIHC cis rs7212590 0.748 rs58681483 chr17:57934654 A/G cg10252138 chr17:58120427 NA -0.62 -6.34 -0.32 7.42e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs10752881 0.935 rs4652771 chr1:183023503 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.68 0.5 3.74e-23 Colorectal cancer; LIHC trans rs561341 0.883 rs2074102 chr17:30228884 G/A cg20587970 chr11:113659929 NA -0.74 -8.45 -0.42 8.62e-16 Hip circumference adjusted for BMI; LIHC trans rs7178375 0.941 rs4779796 chr15:31208050 C/T cg04373760 chr16:53404718 NA 0.62 8.11 0.4 9.22e-15 Hypertriglyceridemia; LIHC cis rs41271473 0.526 rs72765760 chr1:228743222 G/A cg10167378 chr1:228756711 NA 0.61 6.49 0.33 3.04e-10 Chronic lymphocytic leukemia; LIHC cis rs1801251 0.727 rs6437071 chr2:233568793 G/A cg08000102 chr2:233561755 GIGYF2 0.75 12.18 0.55 1.4e-28 Coronary artery disease; LIHC cis rs10927875 0.501 rs9660676 chr1:16279041 C/T cg21385522 chr1:16154831 NA -1.08 -11.31 -0.52 2.09e-25 Dilated cardiomyopathy; LIHC cis rs17376456 0.569 rs12653528 chr5:93212833 T/C cg25358565 chr5:93447407 FAM172A -0.79 -7.78 -0.39 8.89e-14 Diabetic retinopathy; LIHC cis rs4820294 0.669 rs7287358 chr22:38054403 A/G cg10587741 chr22:38071170 LGALS1 0.44 7.93 0.39 3.22e-14 Fat distribution (HIV); LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs4713118 0.824 rs13211701 chr6:27750079 T/C cg20933634 chr6:27740509 NA 0.45 5.96 0.31 6.17e-9 Parkinson's disease; LIHC cis rs8141529 0.509 rs5762864 chr22:29253364 T/C cg02153584 chr22:29168773 CCDC117 0.55 8.12 0.4 8.48e-15 Lymphocyte counts; LIHC cis rs9394841 0.667 rs9471653 chr6:41755410 C/G cg17623882 chr6:41773611 USP49 -0.44 -5.85 -0.3 1.15e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs9790314 0.521 rs13084746 chr3:161086038 G/A cg17135325 chr3:160939158 NMD3 0.42 6.09 0.31 3.07e-9 Morning vs. evening chronotype; LIHC cis rs2412488 1.000 rs2412488 chr4:54330867 A/G cg22241045 chr4:54363911 LNX1 -0.45 -7.07 -0.36 8.51e-12 DNA methylation (variation); LIHC cis rs1419980 0.730 rs11054889 chr12:7773058 C/A cg10578777 chr12:7781093 NA -0.39 -5.78 -0.3 1.67e-8 HDL cholesterol levels; LIHC cis rs933688 1.000 rs1964292 chr5:90743608 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.39 0.66 5.8e-45 Smoking behavior; LIHC cis rs9828933 0.752 rs17069507 chr3:63924956 A/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.78 -8.57 -0.42 3.55e-16 Type 2 diabetes; LIHC cis rs11785400 1.000 rs6988393 chr8:143740596 A/G cg24634471 chr8:143751801 JRK 0.51 8.23 0.41 4.08e-15 Schizophrenia; LIHC trans rs208520 0.690 rs12202913 chr6:66734198 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.78 9.02 0.44 1.34e-17 Exhaled nitric oxide output; LIHC cis rs7534824 0.543 rs72734256 chr1:101390090 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.59 0.38 3.06e-13 Refractive astigmatism; LIHC cis rs600806 0.745 rs4970763 chr1:110006349 G/A cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.57 -0.38 3.46e-13 Intelligence (multi-trait analysis); LIHC cis rs9581857 0.547 rs9319374 chr13:28047587 A/C cg22138327 chr13:27999177 GTF3A 0.76 5.88 0.3 9.84e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs4906332 0.966 rs17679729 chr14:103924312 A/G cg04998671 chr14:104000505 TRMT61A -0.45 -6.09 -0.31 3.11e-9 Coronary artery disease; LIHC cis rs6426558 0.559 rs485234 chr1:227317747 A/G cg10327440 chr1:227177885 CDC42BPA 0.45 6.95 0.35 1.81e-11 Neutrophil percentage of white cells; LIHC cis rs3749237 1.000 rs11717256 chr3:49868520 C/T cg03060546 chr3:49711283 APEH 0.37 5.9 0.3 8.53e-9 Resting heart rate; LIHC cis rs9858542 1.000 rs6770670 chr3:49686682 T/C cg03060546 chr3:49711283 APEH -0.63 -8.45 -0.42 8.71e-16 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4805272 0.626 rs6509072 chr19:29331703 C/G cg04546413 chr19:29218101 NA 0.36 6.28 0.32 1.05e-9 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); LIHC cis rs7772486 0.875 rs7766595 chr6:146364507 A/T cg13319975 chr6:146136371 FBXO30 -0.34 -5.74 -0.3 2.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7843479 0.965 rs878872 chr8:21834567 A/G cg17168535 chr8:21777572 XPO7 0.41 6.52 0.33 2.5e-10 Mean corpuscular volume; LIHC trans rs1034394 0.706 rs5994928 chr22:34818613 G/C cg02641517 chr3:54169983 CACNA2D3 -0.24 -6.1 -0.31 2.93e-9 Major depressive disorder; LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg07234388 chr1:156261841 TMEM79 0.52 9.39 0.45 8.5e-19 Tonsillectomy; LIHC cis rs4908768 0.859 rs4908770 chr1:8711372 G/A cg20416874 chr1:8611966 RERE 0.5 6.98 0.35 1.51e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs8180040 0.629 rs7426969 chr3:47091355 T/C cg16586182 chr3:47516702 SCAP -0.48 -8.69 -0.43 1.57e-16 Colorectal cancer; LIHC cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.92 9.39 0.45 8.53e-19 Platelet count; LIHC cis rs11758351 0.734 rs56220351 chr6:26206884 A/G cg02902477 chr6:26197071 HIST1H3D 0.54 5.86 0.3 1.06e-8 Gout;Renal underexcretion gout; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14033686 chr9:95056052 IARS;SNORA84 -0.47 -6.42 -0.33 4.6e-10 Pancreatic cancer; LIHC cis rs17539620 0.534 rs11541339 chr6:154831643 G/C cg17771515 chr6:154831774 CNKSR3 0.54 5.81 0.3 1.4e-8 Lipoprotein (a) levels; LIHC cis rs78456975 0.527 rs4073862 chr2:1563433 A/G cg01028140 chr2:1542097 TPO -0.39 -6.1 -0.31 2.8e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs951366 0.764 rs823141 chr1:205741426 T/C cg07157834 chr1:205819609 PM20D1 0.65 9.81 0.47 3.41e-20 Menarche (age at onset); LIHC cis rs12472274 0.529 rs11683094 chr2:239118057 G/A cg17459225 chr2:239074497 NA 0.62 9.46 0.46 5.03e-19 Phospholipid levels (plasma); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11651961 chr2:54197711 PSME4 0.5 7.09 0.36 7.92e-12 Lung function (FEV1/FVC); LIHC cis rs3008870 0.755 rs4655660 chr1:67402953 G/A cg02640540 chr1:67518911 SLC35D1 0.41 6.38 0.33 5.76e-10 Lymphocyte percentage of white cells; LIHC cis rs9611565 0.592 rs6519270 chr22:42078666 A/G cg06634786 chr22:41940651 POLR3H 0.56 6.13 0.31 2.47e-9 Vitiligo; LIHC cis rs262150 0.567 rs2040897 chr7:158803848 C/T cg19418458 chr7:158789849 NA -0.32 -5.9 -0.3 8.9e-9 Facial morphology (factor 20); LIHC cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg05590025 chr7:65112418 INTS4L2 -0.62 -6.82 -0.35 4.26e-11 Diabetic kidney disease; LIHC cis rs7903847 0.642 rs7896100 chr10:99156994 C/T cg08345082 chr10:99160200 RRP12 -0.39 -6.58 -0.34 1.81e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11449408 chr17:80856057 TBCD 0.46 6.77 0.34 5.52e-11 Longevity; LIHC cis rs2842992 0.789 rs9364536 chr6:160225559 G/C cg11366901 chr6:160182831 ACAT2 0.93 15.19 0.63 3.32e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs17106184 1.000 rs59524047 chr1:51399215 G/A cg07174182 chr1:51127561 FAF1 -0.75 -7.9 -0.39 3.96e-14 Type 2 diabetes; LIHC trans rs11098499 0.874 rs12502503 chr4:120116255 C/T cg25214090 chr10:38739885 LOC399744 0.45 7.27 0.37 2.49e-12 Corneal astigmatism; LIHC cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg19635926 chr16:89946313 TCF25 0.54 7.3 0.37 2.02e-12 Skin colour saturation; LIHC cis rs11627756 0.918 rs2403070 chr14:103093432 T/C cg12046867 chr14:103022105 NA -0.37 -5.72 -0.3 2.28e-8 Mean platelet volume; LIHC cis rs2016586 0.860 rs5755920 chr22:36103270 G/C cg26342177 chr22:36113512 APOL5 -0.38 -6.33 -0.32 7.74e-10 Body mass index; LIHC cis rs6960043 0.584 rs2189725 chr7:15041873 G/A cg19272540 chr7:15055459 NA 0.25 6.68 0.34 9.83e-11 Type 2 diabetes; LIHC cis rs1670533 1.000 rs604597 chr4:1094151 G/A cg27284194 chr4:1044797 NA -0.61 -8.82 -0.43 5.83e-17 Recombination rate (females); LIHC cis rs6754311 0.731 rs3754686 chr2:136603276 T/C cg17750252 chr2:136567154 LCT 0.34 6.24 0.32 1.32e-9 Mosquito bite size; LIHC cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.56 8.06 0.4 1.27e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1000083 0.748 rs2697555 chr5:96620037 A/G ch.5.96698337R chr5:96672581 NA 0.96 7.3 0.37 2.09e-12 Cisplatin-induced ototoxicity; LIHC cis rs1728785 0.901 rs1183956 chr16:68606726 G/A cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg16049864 chr8:95962084 TP53INP1 -0.63 -11.47 -0.53 5.44e-26 Type 2 diabetes; LIHC cis rs116095464 0.614 rs10059220 chr5:242813 C/T cg22857025 chr5:266934 NA -1.56 -16.35 -0.66 8.71e-45 Breast cancer; LIHC cis rs7772486 0.790 rs9791313 chr6:146266172 T/C cg05347473 chr6:146136440 FBXO30 -0.35 -5.74 -0.3 2.12e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9993613 0.935 rs10019152 chr4:73518770 A/C cg15102770 chr4:73434591 ADAMTS3 -0.39 -5.88 -0.3 9.77e-9 Hip circumference adjusted for BMI;Height; LIHC cis rs10883723 0.810 rs3781289 chr10:104244991 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.49 0.56 9.88e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg08132940 chr7:1081526 C7orf50 -0.81 -6.74 -0.34 6.64e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs988712 0.705 rs879048 chr11:27638934 A/C cg18117895 chr11:27722066 BDNF 0.43 5.85 0.3 1.17e-8 Obesity; LIHC cis rs7193541 0.564 rs4888274 chr16:74706298 A/T cg01733217 chr16:74700730 RFWD3 0.92 22.12 0.77 6.13e-68 Multiple myeloma; LIHC cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg25894440 chr7:65020034 NA -0.55 -6.33 -0.32 7.79e-10 Diabetic kidney disease; LIHC cis rs908922 0.676 rs11584191 chr1:152500428 A/T cg20991723 chr1:152506922 NA -0.52 -9.19 -0.44 3.92e-18 Hair morphology; LIHC cis rs9612 0.848 rs7181 chr19:44270925 G/A cg08581076 chr19:44259116 C19orf61 0.61 7.13 0.36 5.9e-12 Exhaled nitric oxide output; LIHC cis rs7927771 1.000 rs12361031 chr11:47783076 G/A cg20135002 chr11:47629003 NA -0.54 -9.33 -0.45 1.39e-18 Subjective well-being; LIHC cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg21724239 chr8:58056113 NA 0.59 7.62 0.38 2.53e-13 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.966 rs2563265 chr5:140137005 C/T cg26395211 chr5:140044315 WDR55 0.43 6.47 0.33 3.42e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs11190604 1.000 rs2495760 chr10:102318771 T/C cg07080220 chr10:102295463 HIF1AN 0.53 7.12 0.36 6.28e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs870825 0.616 rs1401362 chr4:185643775 G/A cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs72781680 0.848 rs72780199 chr2:24016269 A/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs7833790 0.654 rs6415652 chr8:82702257 G/A cg02079420 chr8:82753780 SNX16 0.34 6.06 0.31 3.63e-9 Diastolic blood pressure; LIHC cis rs4843747 0.671 rs8053377 chr16:88106465 A/G cg00677901 chr16:88017247 BANP 0.51 7.87 0.39 4.67e-14 Menopause (age at onset); LIHC cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.38 0.49 4.12e-22 Total body bone mineral density; LIHC cis rs12479064 0.724 rs112900993 chr2:99948805 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -7.78 -0.39 8.81e-14 Chronic sinus infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26245302 chr6:163148501 PACRG;PARK2 -0.49 -6.84 -0.35 3.61e-11 Pancreatic cancer; LIHC cis rs12887734 0.524 rs722637 chr14:104261723 G/T cg01849466 chr14:104193079 ZFYVE21 0.39 6.02 0.31 4.59e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg09025071 chr16:1593152 IFT140;TMEM204 0.34 6.76 0.34 5.9e-11 Coronary artery disease; LIHC cis rs796364 0.625 rs13035260 chr2:201132377 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.53 -6.23 -0.32 1.35e-9 Schizophrenia; LIHC cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg17971929 chr21:40555470 PSMG1 0.83 10.07 0.48 4.79e-21 Cognitive function; LIHC cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg20887711 chr4:1340912 KIAA1530 -0.47 -7.2 -0.36 3.85e-12 Obesity-related traits; LIHC cis rs6860806 0.507 rs2631362 chr5:131707293 A/G cg24060327 chr5:131705240 SLC22A5 0.83 13.25 0.58 1.21e-32 Breast cancer; LIHC cis rs2153535 0.542 rs1120393 chr6:8486890 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs477692 0.569 rs1711670 chr10:131281115 A/G cg05714579 chr10:131428358 MGMT 0.38 6.03 0.31 4.29e-9 Response to temozolomide; LIHC cis rs2290405 1.000 rs2290405 chr4:946974 A/G cg08222618 chr4:941054 TMEM175 -0.41 -6.87 -0.35 2.96e-11 Systemic sclerosis; LIHC cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.3 0.45 1.66e-18 Bipolar disorder; LIHC trans rs11098499 0.863 rs11098532 chr4:120490726 C/A cg25214090 chr10:38739885 LOC399744 0.58 9.49 0.46 3.93e-19 Corneal astigmatism; LIHC cis rs7659604 0.539 rs11098646 chr4:122729301 T/C cg19748678 chr4:122722346 EXOSC9 0.67 11.07 0.51 1.47e-24 Type 2 diabetes; LIHC cis rs6539267 0.741 rs2279759 chr12:106694988 T/C cg00173435 chr12:106696525 TCP11L2 0.58 7.91 0.39 3.71e-14 Tourette syndrome; LIHC cis rs6701037 0.566 rs1883102 chr1:175136793 T/A cg00958927 chr1:175162553 KIAA0040 0.38 6.27 0.32 1.12e-9 Alcohol dependence; LIHC cis rs769267 0.895 rs2916074 chr19:19530270 C/T cg03709012 chr19:19516395 GATAD2A 1.02 18.2 0.7 3.21e-52 Tonsillectomy; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.8 -14.97 -0.63 2.65e-39 Prudent dietary pattern; LIHC cis rs2758596 1.000 rs2758617 chr1:156160693 A/G cg25208724 chr1:156163844 SLC25A44 0.78 8.57 0.42 3.68e-16 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs9368481 0.569 rs6907403 chr6:26877297 A/C cg12292205 chr6:26970375 C6orf41 0.42 7.07 0.36 8.58e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs6547741 1.000 rs6756238 chr2:27841305 G/A cg27432699 chr2:27873401 GPN1 0.72 11.77 0.54 4.58e-27 Oral cavity cancer; LIHC cis rs7223966 1.000 rs7217982 chr17:61832150 C/T cg05941027 chr17:61774174 LIMD2 0.35 7.29 0.37 2.13e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg05368731 chr17:41323189 NBR1 0.71 12.31 0.55 4.27e-29 Menopause (age at onset); LIHC trans rs2727020 0.894 rs1917328 chr11:49359606 G/A cg15704280 chr7:45808275 SEPT13 -0.74 -11.1 -0.51 1.19e-24 Coronary artery disease; LIHC cis rs11958404 0.789 rs72818150 chr5:157484121 A/G cg05962755 chr5:157440814 NA 1.02 11.85 0.54 2.28e-27 IgG glycosylation; LIHC cis rs13161895 0.887 rs1103811 chr5:179413168 G/A cg06664874 chr5:179499304 RNF130 0.49 6.37 0.33 5.96e-10 LDL cholesterol; LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg00800038 chr16:89945340 TCF25 -0.69 -10.94 -0.51 4.21e-24 Skin colour saturation; LIHC cis rs17401966 0.838 rs946503 chr1:10308631 C/G cg19773385 chr1:10388646 KIF1B 0.39 7.17 0.36 4.71e-12 Hepatocellular carcinoma; LIHC cis rs1030877 1.000 rs2576737 chr2:105891510 C/T cg02079111 chr2:105885981 TGFBRAP1 0.68 12.0 0.54 6.13e-28 Obesity-related traits; LIHC cis rs7264396 0.790 rs6060526 chr20:34225302 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.65 9.97 0.47 9.97e-21 Total cholesterol levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01855760 chr4:68567075 LOC550112;UBA6 0.48 7.13 0.36 6.13e-12 Cognitive function; LIHC cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg02290350 chr8:58132656 NA 0.44 8.57 0.42 3.49e-16 Developmental language disorder (linguistic errors); LIHC cis rs703842 1.000 rs1599932 chr12:58177943 G/A cg18357645 chr12:58087776 OS9 -0.45 -6.98 -0.35 1.49e-11 Multiple sclerosis; LIHC cis rs7474896 0.583 rs10764144 chr10:37975732 G/C cg25427524 chr10:38739819 LOC399744 -0.48 -6.99 -0.35 1.45e-11 Obesity (extreme); LIHC cis rs6691722 0.583 rs7535482 chr1:24695114 A/C cg18323236 chr1:24743029 NIPAL3 0.32 5.8 0.3 1.5e-8 Response to interferon beta in multiple sclerosis; LIHC cis rs4975709 0.531 rs6884044 chr5:1871599 C/T cg14773178 chr5:1868261 NA 0.26 6.81 0.35 4.28e-11 Cardiovascular disease risk factors; LIHC cis rs311392 1.000 rs443599 chr8:55088048 T/C cg11783602 chr8:55087084 NA -0.34 -6.68 -0.34 9.79e-11 Pelvic organ prolapse (moderate/severe); LIHC cis rs4808199 0.895 rs10403731 chr19:19469296 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.55 7.98 0.4 2.2e-14 Nonalcoholic fatty liver disease; LIHC trans rs7668874 0.774 rs1816328 chr4:116806243 T/A cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs11628318 0.614 rs7155804 chr14:103114945 A/G cg23461800 chr14:103021989 NA 0.42 5.96 0.31 6.38e-9 Platelet count; LIHC cis rs10463316 0.962 rs61647401 chr5:150743076 T/C cg03212797 chr5:150827313 SLC36A1 -0.41 -6.21 -0.32 1.53e-9 Metabolite levels (Pyroglutamine); LIHC cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg08888203 chr3:10149979 C3orf24 0.62 6.86 0.35 3.27e-11 Alzheimer's disease; LIHC cis rs7312933 0.703 rs11181378 chr12:42600658 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 7.59 0.38 3.1e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs8017423 0.967 rs11627429 chr14:90689232 G/A cg14092571 chr14:90743983 NA 0.4 6.29 0.32 9.48e-10 Mortality in heart failure; LIHC cis rs1552244 0.608 rs7615408 chr3:10000186 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.61 8.5 0.42 5.98e-16 Alzheimer's disease; LIHC cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg03517284 chr6:25882590 NA -0.52 -6.66 -0.34 1.09e-10 Intelligence (multi-trait analysis); LIHC cis rs8060686 0.545 rs17688076 chr16:68286427 C/A cg05110241 chr16:68378359 PRMT7 -0.61 -6.92 -0.35 2.23e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs7727544 0.735 rs2569266 chr5:131706791 T/C cg07395648 chr5:131743802 NA 0.32 6.64 0.34 1.27e-10 Blood metabolite levels; LIHC cis rs9300255 0.602 rs1727296 chr12:123647725 G/C cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs208515 0.525 rs12193560 chr6:66690457 A/T cg07460842 chr6:66804631 NA 0.79 8.97 0.44 1.94e-17 Exhaled nitric oxide levels; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg14709524 chr16:89940631 TCF25 0.51 6.56 0.33 1.97e-10 Skin colour saturation; LIHC cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg00091569 chr3:40428383 ENTPD3 -0.4 -6.79 -0.34 4.83e-11 Renal cell carcinoma; LIHC cis rs8103278 1.000 rs9676288 chr19:46292060 G/T cg14061069 chr19:46274453 DMPK -0.55 -8.57 -0.42 3.73e-16 Coronary artery disease; LIHC cis rs876084 0.505 rs66488706 chr8:121132894 C/T cg06265175 chr8:121136014 COL14A1 0.48 7.57 0.38 3.49e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10733682 0.524 rs10987422 chr9:129462687 C/A cg00232160 chr9:129468157 NA 0.38 6.73 0.34 7.16e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7903847 0.642 rs10882909 chr10:99137998 G/C cg20016023 chr10:99160130 RRP12 -0.42 -6.64 -0.34 1.24e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9916302 0.821 rs12938268 chr17:37572139 G/A cg07936489 chr17:37558343 FBXL20 -0.82 -13.01 -0.58 1e-31 Glomerular filtration rate (creatinine); LIHC cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.54 0.33 2.22e-10 Bipolar disorder; LIHC cis rs2658782 0.526 rs3020062 chr11:93061159 T/C cg15737290 chr11:93063684 CCDC67 0.46 5.96 0.31 6.13e-9 Pulmonary function decline; LIHC cis rs72781680 1.000 rs75046532 chr2:24167267 A/G cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs17125944 0.505 rs2295827 chr14:53174981 C/T cg00686598 chr14:53173677 PSMC6 1.29 15.76 0.65 1.88e-42 Alzheimer's disease (late onset); LIHC cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7843479 0.601 rs11780532 chr8:21838670 T/A cg17168535 chr8:21777572 XPO7 0.56 9.97 0.47 9.78e-21 Mean corpuscular volume; LIHC cis rs12477438 0.501 rs7608938 chr2:99782226 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs735860 0.572 rs186003 chr6:53185124 A/C cg10236188 chr6:53219634 NA 0.41 7.49 0.38 5.97e-13 Glaucoma; LIHC cis rs11055008 0.935 rs10845601 chr12:12820134 A/G cg04607235 chr12:12878440 APOLD1 0.53 7.37 0.37 1.27e-12 Pulse pressure; LIHC cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg15691649 chr6:25882328 NA 0.45 5.76 0.3 1.92e-8 Intelligence (multi-trait analysis); LIHC cis rs9818758 0.607 rs9847839 chr3:49289003 T/C cg06212747 chr3:49208901 KLHDC8B -0.65 -5.77 -0.3 1.75e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9868809 0.772 rs28452701 chr3:48708575 C/T cg07636037 chr3:49044803 WDR6 -0.64 -7.12 -0.36 6.5e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs950169 0.922 rs8037078 chr15:84818871 A/G cg17507749 chr15:85114479 UBE2QP1 -0.75 -8.88 -0.43 3.93e-17 Schizophrenia; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg09952564 chr10:5979174 FBXO18 0.52 6.39 0.33 5.46e-10 Lung function (FEV1); LIHC cis rs801193 1.000 rs11773829 chr7:66141074 G/A cg14393609 chr7:65229607 NA -0.37 -5.81 -0.3 1.46e-8 Aortic root size; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg19355462 chr6:15248936 JARID2 -0.47 -6.04 -0.31 4.09e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2292096 1.000 rs35442900 chr1:200779144 T/C cg11814564 chr1:200748674 CAMSAP1L1 -0.45 -5.92 -0.3 7.95e-9 Epilepsy; LIHC cis rs13108904 0.901 rs12509700 chr4:1296321 A/G cg13395646 chr4:1353034 KIAA1530 -0.4 -6.2 -0.32 1.59e-9 Obesity-related traits; LIHC cis rs3617 0.573 rs2336668 chr3:52919096 G/T cg11645453 chr3:52864694 ITIH4 -0.23 -6.11 -0.31 2.74e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs2463822 0.858 rs2463836 chr11:62126494 A/G cg06239285 chr11:62104954 ASRGL1 0.91 6.85 0.35 3.55e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs2979489 0.945 rs11992441 chr8:30313649 A/G cg26383811 chr8:30366931 RBPMS 0.71 12.0 0.54 6.35e-28 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs1461503 0.966 rs11218905 chr11:122840303 A/G cg14473756 chr11:122847823 NA 0.36 6.79 0.34 5.08e-11 Menarche (age at onset); LIHC cis rs1008375 0.800 rs35463363 chr4:17613423 G/T cg02297831 chr4:17616191 MED28 0.43 6.04 0.31 3.93e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2180341 0.960 rs7766942 chr6:127691323 G/T cg24812749 chr6:127587940 RNF146 1.03 15.33 0.64 9.68e-41 Breast cancer; LIHC trans rs1814175 0.817 rs7947526 chr11:49983654 T/C cg03929089 chr4:120376271 NA -0.89 -18.36 -0.7 7.18e-53 Height; LIHC cis rs1023500 0.573 rs1807494 chr22:42474138 C/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.15 -0.32 2.18e-9 Schizophrenia; LIHC cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg17971929 chr21:40555470 PSMG1 0.85 10.53 0.49 1.2e-22 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11753193 chr8:94753277 RBM12B -0.41 -6.09 -0.31 3.07e-9 Cognitive function; LIHC cis rs11764590 0.694 rs10235664 chr7:2086814 T/C cg23043544 chr7:2124092 MAD1L1 -0.42 -6.97 -0.35 1.65e-11 Neuroticism; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.23 -0.32 1.37e-9 Total body bone mineral density; LIHC cis rs12995491 0.933 rs34029976 chr2:88537797 T/C cg24977027 chr2:88469347 THNSL2 -0.35 -6.0 -0.31 5.17e-9 Response to metformin (IC50); LIHC trans rs11088226 0.692 rs2833861 chr21:33882345 C/T cg09050820 chr6:167586206 TCP10L2 0.44 6.47 0.33 3.35e-10 Gastritis; LIHC cis rs1577917 0.958 rs1414199 chr6:86522370 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.33 -5.85 -0.3 1.14e-8 Response to antipsychotic treatment; LIHC cis rs6840360 0.550 rs4696288 chr4:152621150 A/C cg22705602 chr4:152727874 NA -0.4 -7.13 -0.36 5.92e-12 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12427896 chr2:111880694 BCL2L11 0.5 7.76 0.39 1.01e-13 Pancreatic cancer; LIHC cis rs6088590 1.000 rs6119524 chr20:33373813 C/T cg24642439 chr20:33292090 TP53INP2 0.78 10.63 0.5 5.31e-23 Coronary artery disease; LIHC cis rs57244997 0.725 rs7738080 chr6:162413377 A/G cg17173639 chr6:162384350 PARK2 -0.53 -6.96 -0.35 1.71e-11 Mosquito bite size; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg10774155 chr7:65338427 VKORC1L1 0.45 6.55 0.33 2.06e-10 Calcium levels; LIHC cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg00684032 chr4:1343700 KIAA1530 0.35 5.79 0.3 1.58e-8 Obesity-related traits; LIHC cis rs1185460 1.000 rs15818 chr11:118952173 A/G cg23280166 chr11:118938394 VPS11 0.49 6.24 0.32 1.27e-9 Coronary artery disease; LIHC cis rs112721625 1 rs112721625 chr17:57927426 AT/A cg13753209 chr17:57696993 CLTC 0.53 8.64 0.42 2.19e-16 Monocyte count; LIHC cis rs4407350 0.870 rs4823329 chr22:44910117 T/C cg04154583 chr22:44889756 LDOC1L 0.3 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.89 0.57 2.94e-31 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg23758822 chr17:41437982 NA 0.95 17.95 0.7 3.02e-51 Menopause (age at onset); LIHC cis rs7149337 0.836 rs34953083 chr14:51672432 A/G cg23942311 chr14:51606299 NA 0.32 6.21 0.32 1.51e-9 Cancer; LIHC cis rs8017423 0.630 rs4900038 chr14:90821677 A/G cg04374321 chr14:90722782 PSMC1 -0.49 -7.27 -0.37 2.46e-12 Mortality in heart failure; LIHC cis rs9611519 0.929 rs9611465 chr22:41426139 G/A cg03806693 chr22:41940476 POLR3H -0.69 -7.66 -0.38 1.92e-13 Neuroticism; LIHC cis rs6665290 0.669 rs34267809 chr1:227176162 C/G cg10327440 chr1:227177885 CDC42BPA -1.14 -27.63 -0.83 3.84e-89 Myeloid white cell count; LIHC cis rs7223966 1.000 rs7216798 chr17:61740963 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.92e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9814567 1.000 rs6804770 chr3:134230234 A/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.95 -0.31 6.7e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11031096 0.655 rs34295904 chr11:4206701 C/A cg18678763 chr11:4115507 RRM1 -0.4 -5.82 -0.3 1.35e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6782228 0.606 rs2712419 chr3:128340896 T/C cg16766828 chr3:128327626 NA -0.41 -6.46 -0.33 3.69e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg19318889 chr4:1322082 MAEA 0.46 7.62 0.38 2.57e-13 Obesity-related traits; LIHC cis rs10892173 0.566 rs111578166 chr11:117666714 G/T cg21640587 chr11:117668038 DSCAML1 0.55 6.92 0.35 2.19e-11 Myopia; LIHC cis rs1434579 0.652 rs7249704 chr19:44939360 A/G cg15540054 chr19:45004280 ZNF180 0.65 9.91 0.47 1.58e-20 Tuberculosis; LIHC cis rs7918232 0.800 rs7907981 chr10:27444329 T/C cg14442939 chr10:27389572 ANKRD26 0.67 7.04 0.36 1.07e-11 Breast cancer; LIHC cis rs748404 0.697 rs567357 chr15:43571390 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.7 0.34 8.66e-11 Lung cancer; LIHC cis rs8027181 0.839 rs62017600 chr15:73072236 T/A cg25996835 chr15:72978165 BBS4;HIGD2B 0.49 7.5 0.38 5.49e-13 Triglyceride levels; LIHC cis rs7116495 1.000 rs659513 chr11:71812411 C/T cg26138937 chr11:71823887 C11orf51 0.83 8.05 0.4 1.39e-14 Severe influenza A (H1N1) infection; LIHC cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg08888203 chr3:10149979 C3orf24 0.56 6.37 0.33 6.28e-10 Alzheimer's disease; LIHC cis rs611744 0.967 rs628843 chr8:109196115 C/G cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs4919087 1.000 rs11189132 chr10:99086195 G/C cg25902810 chr10:99078978 FRAT1 -0.67 -10.01 -0.48 7.58e-21 Monocyte count; LIHC cis rs965469 0.779 rs6139092 chr20:3334651 T/C cg25506879 chr20:3388711 C20orf194 -0.54 -6.3 -0.32 9.4e-10 IFN-related cytopenia; LIHC trans rs1728785 1.000 rs889561 chr16:68605741 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.3 0.32 8.94e-10 Ulcerative colitis; LIHC cis rs769267 0.930 rs10282 chr19:19619317 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.4 6.08 0.31 3.17e-9 Tonsillectomy; LIHC cis rs8072100 1.000 rs4375701 chr17:45712218 C/T cg15066416 chr17:45501628 LOC100272146;C17orf57 -0.36 -5.93 -0.31 7.22e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs13118159 0.836 rs2276903 chr4:1343405 A/G cg05025164 chr4:1340916 KIAA1530 0.47 6.93 0.35 2.17e-11 Longevity; LIHC cis rs1018836 0.564 rs7821994 chr8:91700916 C/T cg16814680 chr8:91681699 NA -0.96 -18.11 -0.7 7.31e-52 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7264396 0.563 rs2425081 chr20:34299733 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC cis rs172166 0.694 rs1225716 chr6:28113746 A/C cg23485639 chr6:28045615 ZNF165 0.38 5.96 0.31 6.31e-9 Cardiac Troponin-T levels; LIHC cis rs10197940 0.662 rs4592848 chr2:152337822 G/A cg06191203 chr2:152266755 RIF1 -0.47 -7.82 -0.39 6.41e-14 Lung cancer; LIHC cis rs7296418 0.699 rs11608297 chr12:123826642 T/C cg00376283 chr12:123451042 ABCB9 0.62 10.35 0.49 5.15e-22 Platelet count; LIHC cis rs10744422 1.000 rs7138398 chr12:123341833 G/C cg22842854 chr12:123319900 HIP1R -0.74 -9.73 -0.47 6.52e-20 Schizophrenia; LIHC cis rs9733 0.687 rs12410050 chr1:150857141 A/G cg13175981 chr1:150552382 MCL1 0.53 7.42 0.37 9.39e-13 Tonsillectomy; LIHC cis rs8103278 0.860 rs11669073 chr19:46324880 C/T cg14061069 chr19:46274453 DMPK -0.55 -8.41 -0.41 1.15e-15 Coronary artery disease; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg01893041 chr5:67583972 PIK3R1 -0.43 -6.32 -0.32 8.29e-10 Urinary tract infection frequency; LIHC cis rs6951245 1.000 rs75488469 chr7:1102122 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.03 0.31 4.34e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2180341 0.960 rs7751865 chr6:127683040 G/A cg27446573 chr6:127587934 RNF146 1.05 16.49 0.67 2.21e-45 Breast cancer; LIHC cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg17971929 chr21:40555470 PSMG1 -0.48 -7.19 -0.36 4.24e-12 Cognitive function; LIHC cis rs8027181 0.797 rs8033580 chr15:72994968 C/A cg25632853 chr15:73088954 NA 0.35 5.89 0.3 9.02e-9 Triglyceride levels; LIHC cis rs7309 0.935 rs11884495 chr2:162059969 A/T cg08807892 chr2:162101083 NA 0.45 7.64 0.38 2.14e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs6977660 0.714 rs10249635 chr7:19787090 A/G cg07541023 chr7:19748670 TWISTNB 0.49 7.24 0.36 3e-12 Thyroid stimulating hormone; LIHC cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.688 rs10744287 chr12:123077485 T/A cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.74 -0.39 1.12e-13 Body mass index; LIHC cis rs8067545 0.750 rs4924803 chr17:19991806 C/T cg13482628 chr17:19912719 NA 0.49 8.26 0.41 3.31e-15 Schizophrenia; LIHC cis rs9858542 0.953 rs71324979 chr3:49619651 T/C cg03060546 chr3:49711283 APEH -0.52 -7.01 -0.35 1.25e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs847649 0.731 rs12666317 chr7:102704135 C/T cg18108683 chr7:102477205 FBXL13 0.41 6.09 0.31 3.07e-9 Morning vs. evening chronotype; LIHC cis rs921968 0.565 rs3731876 chr2:219602819 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.42 -0.33 4.66e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg12311346 chr5:56204834 C5orf35 0.65 8.39 0.41 1.28e-15 Initial pursuit acceleration; LIHC cis rs12220238 0.818 rs10824082 chr10:75904080 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.83 0.35 3.92e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9646303 0.778 rs9940620 chr16:87511877 A/T cg08565003 chr16:87447920 ZCCHC14 -0.31 -5.79 -0.3 1.58e-8 Major depressive disorder; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg00280220 chr17:61926910 NA 0.43 6.87 0.35 3.04e-11 Prudent dietary pattern; LIHC cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg10210624 chr19:58662595 ZNF329 0.73 7.33 0.37 1.65e-12 Cholesterol, total; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08080923 chr19:47763943 CCDC9 0.44 6.81 0.35 4.52e-11 Longevity; LIHC cis rs2580764 0.598 rs6755468 chr2:55240026 A/C cg09592903 chr2:55203963 RTN4 -0.71 -12.91 -0.57 2.49e-31 Mean platelet volume; LIHC cis rs782590 0.582 rs2627767 chr2:55926815 A/T cg03859395 chr2:55845619 SMEK2 0.62 9.93 0.47 1.33e-20 Metabolic syndrome; LIHC trans rs7618501 0.633 rs35065728 chr3:50009176 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.55 9.09 0.44 8.16e-18 Intelligence (multi-trait analysis); LIHC cis rs7904368 0.951 rs7074647 chr10:16855455 T/C cg14835575 chr10:16859367 RSU1 0.59 8.2 0.41 5e-15 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs921968 0.565 rs1529382 chr2:219626489 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6963495 0.745 rs73190169 chr7:105160500 A/G cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2153535 0.580 rs1577470 chr6:8462426 G/A cg23788917 chr6:8435910 SLC35B3 0.62 8.71 0.43 1.34e-16 Motion sickness; LIHC cis rs6430585 0.640 rs6716070 chr2:136544651 G/T cg07169764 chr2:136633963 MCM6 -1.1 -16.31 -0.66 1.26e-44 Corneal structure; LIHC trans rs1814175 0.669 rs12416837 chr11:49669761 G/T cg15704280 chr7:45808275 SEPT13 -0.64 -11.12 -0.52 1.03e-24 Height; LIHC cis rs3768617 0.510 rs10797846 chr1:183087485 A/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs6951245 0.554 rs2070118 chr7:1132505 G/A cg24642844 chr7:1081250 C7orf50 -0.53 -5.81 -0.3 1.41e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4561483 0.801 rs33643 chr16:11986149 A/G cg08843971 chr16:11963173 GSPT1 -0.43 -8.48 -0.42 6.96e-16 Testicular germ cell tumor; LIHC cis rs644799 1.000 rs627568 chr11:95569253 A/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.8 0.47 3.89e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2204008 0.688 rs12824232 chr12:38175901 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC trans rs75804782 0.521 rs56340711 chr2:239440080 A/T cg01134436 chr17:81009848 B3GNTL1 0.71 6.15 0.32 2.15e-9 Morning vs. evening chronotype;Chronotype; LIHC cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg02290350 chr8:58132656 NA 0.41 8.51 0.42 5.56e-16 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs1577472 chr6:8486215 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs2075371 1.000 rs2544218 chr7:133992315 C/A cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC cis rs4684776 1.000 rs6762035 chr3:11423759 T/G cg00170343 chr3:11313890 ATG7 -0.43 -5.93 -0.31 7.49e-9 Small vessel stroke; LIHC cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs77106637 0.530 rs1785212 chr11:72462375 T/C cg03713592 chr11:72463424 ARAP1 0.55 6.17 0.32 1.91e-9 Type 2 diabetes; LIHC cis rs7208859 0.673 rs11080135 chr17:29176481 A/G cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs11711311 1.000 rs2242109 chr3:113434100 G/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.26 0.45 2.39e-18 IgG glycosylation; LIHC cis rs801193 1.000 rs2055682 chr7:66260289 A/G cg18876405 chr7:65276391 NA 0.41 7.09 0.36 7.88e-12 Aortic root size; LIHC cis rs2576037 0.583 rs8086286 chr18:44467515 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.69 -11.22 -0.52 4.29e-25 Personality dimensions; LIHC cis rs7572733 0.534 rs1518363 chr2:198810131 C/T cg03934865 chr2:198174659 NA 0.48 7.02 0.35 1.23e-11 Dermatomyositis; LIHC trans rs6539288 0.803 rs10778517 chr12:107341664 G/T cg15577575 chr1:145470249 ANKRD34A;POLR3GL 0.43 6.43 0.33 4.2e-10 Total body bone mineral density; LIHC cis rs6674176 0.593 rs3791120 chr1:44431715 T/C cg12908607 chr1:44402522 ARTN -0.5 -8.45 -0.42 8.77e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2929278 0.617 rs663214 chr15:44113782 T/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.36 -5.94 -0.31 7.14e-9 Schizophrenia; LIHC cis rs922107 0.713 rs10801744 chr1:89953544 C/T cg15422784 chr1:90023713 LRRC8B 0.46 7.4 0.37 1.06e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs3096299 0.935 rs3114890 chr16:89449546 C/G cg02187348 chr16:89574699 SPG7 0.51 7.42 0.37 9.39e-13 Multiple myeloma (IgH translocation); LIHC cis rs9311474 0.607 rs4234633 chr3:52557038 C/T cg10802521 chr3:52805072 NEK4 -0.39 -6.45 -0.33 3.86e-10 Electroencephalogram traits; LIHC cis rs597539 0.652 rs569777 chr11:68706848 G/A cg04772025 chr11:68637568 NA 0.49 6.31 0.32 8.85e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.85 0.3 1.17e-8 Menopause (age at onset); LIHC cis rs7312933 0.531 rs2406674 chr12:42720150 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.02 -0.4 1.66e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4819052 0.808 rs2246697 chr21:46689999 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 11.81 0.54 3.03e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7582180 0.652 rs11694700 chr2:100936637 C/T cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.645 rs1963215 chr11:49931486 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs9291683 0.588 rs2240721 chr4:10020564 G/A cg11266682 chr4:10021025 SLC2A9 0.33 7.11 0.36 6.63e-12 Bone mineral density; LIHC cis rs2236918 1.000 rs1627006 chr1:242038004 C/T cg17736920 chr1:242011382 EXO1 0.57 8.32 0.41 2.1e-15 Menopause (age at onset); LIHC cis rs56235845 0.694 rs11749830 chr5:176766547 G/A cg17509989 chr5:176798049 RGS14 0.63 8.43 0.41 9.770000000000001e-16 Hemoglobin concentration;Hematocrit; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09706180 chr15:50647709 GABPB1;FLJ10038;LOC100129387 0.43 6.08 0.31 3.19e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7666738 0.830 rs17486413 chr4:99060544 G/T cg05340658 chr4:99064831 C4orf37 0.67 11.55 0.53 2.71e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs703842 0.616 rs10877023 chr12:58224199 C/A cg18357645 chr12:58087776 OS9 -0.43 -6.42 -0.33 4.66e-10 Multiple sclerosis; LIHC cis rs7959452 0.535 rs7133487 chr12:69774377 G/A cg14784868 chr12:69753453 YEATS4 0.94 20.34 0.74 7.61e-61 Blood protein levels; LIHC cis rs6570726 0.846 rs973856 chr6:145781916 C/T cg23711669 chr6:146136114 FBXO30 -0.52 -9.13 -0.44 5.93e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 1.000 rs4665819 chr2:26309073 A/G cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.02e-15 Gut microbiome composition (summer); LIHC cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg11645453 chr3:52864694 ITIH4 0.22 6.04 0.31 3.96e-9 Bipolar disorder; LIHC cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg03517284 chr6:25882590 NA -0.64 -9.12 -0.44 6.73e-18 Blood metabolite levels; LIHC cis rs11098499 0.909 rs7681978 chr4:120383775 T/C cg09307838 chr4:120376055 NA 0.77 12.02 0.54 5.37e-28 Corneal astigmatism; LIHC cis rs6733011 0.508 rs4850889 chr2:99521385 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.4 -6.57 -0.33 1.83e-10 Bipolar disorder; LIHC cis rs11583043 1.000 rs7535068 chr1:101490329 T/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.09 0.4 1.02e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7116495 0.609 rs4944243 chr11:71674354 T/C cg10381502 chr11:71823885 C11orf51 -1.02 -8.51 -0.42 5.38e-16 Severe influenza A (H1N1) infection; LIHC cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg11764359 chr7:65958608 NA -0.57 -5.95 -0.31 6.6e-9 Diabetic kidney disease; LIHC cis rs317689 0.690 rs607797 chr12:69646010 T/C cg20891283 chr12:69753455 YEATS4 0.48 6.98 0.35 1.55e-11 Response to diuretic therapy; LIHC cis rs6951245 0.938 rs112425403 chr7:1071531 A/G cg24642844 chr7:1081250 C7orf50 -0.94 -9.38 -0.45 9.6e-19 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1914816 0.941 rs2456027 chr15:76568209 G/A cg03037974 chr15:76606532 NA -0.61 -6.62 -0.34 1.4e-10 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs875971 0.798 rs6460304 chr7:65964728 G/A cg18252515 chr7:66147081 NA -0.44 -6.3 -0.32 9.28e-10 Aortic root size; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg02869306 chr7:64672164 INTS4L1 -0.29 -6.41 -0.33 4.84e-10 Calcium levels; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25389065 chr2:75938167 C2orf3 -0.5 -6.08 -0.31 3.27e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12477438 0.765 rs2309521 chr2:99592069 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.55 -0.38 3.87e-13 Chronic sinus infection; LIHC cis rs10242455 0.571 rs41258334 chr7:99271808 T/C cg18809830 chr7:99032528 PTCD1 -0.86 -6.7 -0.34 8.38e-11 Blood metabolite levels; LIHC cis rs2439831 0.850 rs11856795 chr15:44160582 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.6 7.25 0.37 2.74e-12 Lung cancer in ever smokers; LIHC cis rs7635838 0.892 rs9823197 chr3:11503133 A/T cg00170343 chr3:11313890 ATG7 0.41 6.39 0.33 5.38e-10 HDL cholesterol; LIHC cis rs11166927 0.967 rs56343024 chr8:140803580 G/A cg16909799 chr8:140841666 TRAPPC9 0.5 7.86 0.39 5e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC trans rs208520 0.690 rs207118 chr6:66788948 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.84 -9.07 -0.44 9.28e-18 Exhaled nitric oxide output; LIHC cis rs9790314 0.582 rs11922752 chr3:160600599 G/C cg03342759 chr3:160939853 NMD3 0.57 7.44 0.37 8.19e-13 Morning vs. evening chronotype; LIHC cis rs9309473 1.000 rs6705489 chr2:73648811 G/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.5 -0.33 2.9e-10 Metabolite levels; LIHC cis rs4474465 1.000 rs11237495 chr11:78155090 A/G cg02023728 chr11:77925099 USP35 0.36 6.37 0.33 5.99e-10 Alzheimer's disease (survival time); LIHC cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs3106136 0.967 rs12645192 chr4:95181525 C/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.89 -0.39 4.17e-14 Capecitabine sensitivity; LIHC cis rs7246657 0.882 rs10412043 chr19:37826626 A/C cg23950597 chr19:37808831 NA -0.44 -5.92 -0.3 7.76e-9 Coronary artery calcification; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01330391 chr1:26324448 PAFAH2 0.5 6.48 0.33 3.13e-10 Pancreatic cancer; LIHC cis rs13191362 1.000 rs13193282 chr6:163015442 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.62 5.82 0.3 1.36e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs55665837 1.000 rs12276938 chr11:14463488 C/G cg19336497 chr11:14380999 RRAS2 -0.44 -7.97 -0.4 2.46e-14 Vitamin D levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg09242721 chr3:3168535 TRNT1 0.47 6.53 0.33 2.31e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1801251 0.928 rs737028 chr2:233640750 T/C cg25237894 chr2:233734115 C2orf82 0.57 11.16 0.52 7.26e-25 Coronary artery disease; LIHC cis rs941408 1.000 rs1736179 chr19:2795516 T/A cg06609049 chr19:2785107 THOP1 0.61 9.73 0.47 6.76e-20 Total cholesterol levels; LIHC cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg09323728 chr8:95962352 TP53INP1 -0.3 -6.43 -0.33 4.17e-10 Type 2 diabetes; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg06873352 chr17:61820015 STRADA 0.72 12.49 0.56 9.37e-30 Prudent dietary pattern; LIHC cis rs6964587 0.869 rs2374519 chr7:91541481 T/C cg17063962 chr7:91808500 NA -0.98 -18.72 -0.71 2.45e-54 Breast cancer; LIHC cis rs7572733 0.514 rs770659 chr2:198669754 G/C cg10820045 chr2:198174542 NA 0.47 7.03 0.36 1.12e-11 Dermatomyositis; LIHC cis rs2439831 0.681 rs1549525 chr15:43627855 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.91 17.43 0.69 3.8e-49 Lung cancer in ever smokers; LIHC cis rs68170813 0.559 rs7779062 chr7:106880195 T/A cg02696742 chr7:106810147 HBP1 -0.53 -6.28 -0.32 1.05e-9 Coronary artery disease; LIHC cis rs826838 0.935 rs1684407 chr12:39127270 C/T cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.4e-8 Heart rate; LIHC trans rs1005277 0.505 rs10827835 chr10:38150709 G/A cg23533926 chr12:111358616 MYL2 0.32 6.19 0.32 1.69e-9 Extrinsic epigenetic age acceleration; LIHC cis rs12497850 0.931 rs6446205 chr3:49035211 C/T cg07636037 chr3:49044803 WDR6 0.94 16.71 0.67 3.05e-46 Parkinson's disease; LIHC cis rs875971 0.737 rs7803424 chr7:65880605 T/C cg11764359 chr7:65958608 NA 0.91 16.97 0.68 2.84e-47 Aortic root size; LIHC cis rs2952156 0.920 rs2517951 chr17:37853097 C/T cg00129232 chr17:37814104 STARD3 -0.51 -9.47 -0.46 4.82e-19 Asthma; LIHC cis rs9790314 0.690 rs9860738 chr3:160843290 G/A cg03342759 chr3:160939853 NMD3 -0.72 -11.07 -0.51 1.46e-24 Morning vs. evening chronotype; LIHC cis rs3008870 1.000 rs3008853 chr1:67385488 C/T cg02640540 chr1:67518911 SLC35D1 0.42 5.78 0.3 1.64e-8 Lymphocyte percentage of white cells; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.8 -0.35 4.7e-11 Total body bone mineral density; LIHC cis rs11718455 0.881 rs17076257 chr3:44006787 C/T cg08738300 chr3:44038990 NA 0.52 8.99 0.44 1.74e-17 Coronary artery disease; LIHC cis rs1577917 0.816 rs12664099 chr6:86648572 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.38 -6.96 -0.35 1.71e-11 Response to antipsychotic treatment; LIHC cis rs597539 0.617 rs669659 chr11:68635623 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.77 11.31 0.52 2.02e-25 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1580019 0.922 rs1466147 chr7:32486262 C/T cg07520158 chr7:32535189 LSM5;AVL9 0.5 6.8 0.34 4.79e-11 Cognitive ability; LIHC trans rs1814175 0.935 rs1827017 chr11:49632592 C/G cg15704280 chr7:45808275 SEPT13 -0.99 -21.3 -0.76 1.08e-64 Height; LIHC cis rs5769765 0.817 rs9616212 chr22:50317687 G/A cg02269571 chr22:50332266 NA -0.66 -9.04 -0.44 1.15e-17 Schizophrenia; LIHC cis rs6445975 0.715 rs6790764 chr3:58265950 C/T cg23715586 chr3:58305044 RPP14 -0.35 -6.07 -0.31 3.42e-9 Systemic lupus erythematosus; LIHC cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg00166722 chr3:10149974 C3orf24 0.47 5.79 0.3 1.58e-8 Alzheimer's disease; LIHC cis rs9303401 0.659 rs35797125 chr17:56736547 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs7000551 0.715 rs2469745 chr8:22343464 C/T cg12081754 chr8:22256438 SLC39A14 0.48 7.84 0.39 5.71e-14 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2243480 1.000 rs778691 chr7:65873092 G/C cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs7208487 0.684 rs12449852 chr17:37632088 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -11.99 -0.54 6.61e-28 Primary biliary cholangitis;Glomerular filtration rate in non diabetics (creatinine); LIHC cis rs2066819 1.000 rs2371494 chr12:56728000 G/A cg26734620 chr12:56694298 CS 1.0 10.11 0.48 3.46e-21 Psoriasis vulgaris; LIHC cis rs1577917 0.740 rs9344542 chr6:86393905 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.48 9.51 0.46 3.4e-19 Response to antipsychotic treatment; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19575804 chr20:22559456 C20orf56 0.26 6.73 0.34 7.09e-11 Cognitive function; LIHC cis rs11792861 0.816 rs7027263 chr9:111699569 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.87 0.43 4.22e-17 Menarche (age at onset); LIHC cis rs10508774 1.000 rs11815157 chr10:32833598 A/G cg01819863 chr10:32635814 EPC1 0.65 6.06 0.31 3.66e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02951695 chr10:134400351 INPP5A -0.44 -6.6 -0.34 1.61e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9470361 0.524 rs7740181 chr6:36624111 C/T cg08179530 chr6:36648295 CDKN1A 0.43 6.37 0.33 5.97e-10 QRS complex (Cornell);QRS duration;Left ventricular fractional shortening; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.84 0.63 8.42e-39 Prudent dietary pattern; LIHC cis rs748404 0.631 rs7166812 chr15:43644760 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.56 8.89 0.43 3.56e-17 Lung cancer; LIHC cis rs9457247 1.000 rs404222 chr6:167402150 G/A cg12798992 chr6:167411361 FGFR1OP 0.53 8.2 0.41 4.87e-15 Crohn's disease; LIHC cis rs2842992 0.915 rs1967802 chr6:160097791 G/A cg11366901 chr6:160182831 ACAT2 0.95 15.3 0.64 1.28e-40 Age-related macular degeneration (geographic atrophy); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20956633 chr20:19997839 NAA20 0.45 6.06 0.31 3.53e-9 Lung function (FEV1/FVC); LIHC cis rs9399137 0.507 rs28384513 chr6:135376209 T/G cg24558204 chr6:135376177 HBS1L 0.64 10.81 0.5 1.25e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs734999 0.967 rs10797434 chr1:2511280 C/T cg18854424 chr1:2615690 NA 0.33 7.08 0.36 8.34e-12 Ulcerative colitis; LIHC trans rs3780486 0.834 rs75443249 chr9:33149207 A/G cg04842962 chr6:43655489 MRPS18A 0.93 16.83 0.67 1.02e-46 IgG glycosylation; LIHC cis rs7584330 0.666 rs72620816 chr2:238353604 C/T cg14458575 chr2:238380390 NA 0.53 7.46 0.37 7.18e-13 Prostate cancer; LIHC cis rs2066819 1.000 rs17118409 chr12:56630764 G/A cg26734620 chr12:56694298 CS 1.2 9.66 0.46 1.13e-19 Psoriasis vulgaris; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16266895 chr12:101674004 UTP20 0.4 6.32 0.32 8.11e-10 Cognitive function; LIHC cis rs10464366 0.746 rs62442210 chr7:39146328 G/T cg10621924 chr7:39171070 POU6F2 0.42 6.42 0.33 4.48e-10 IgG glycosylation; LIHC cis rs9916302 0.851 rs2338795 chr17:37399364 T/G cg07936489 chr17:37558343 FBXL20 -0.8 -12.83 -0.57 4.94e-31 Glomerular filtration rate (creatinine); LIHC cis rs11122272 0.735 rs2247132 chr1:231493359 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -11.0 -0.51 2.73e-24 Hemoglobin concentration; LIHC cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg20295408 chr7:1910781 MAD1L1 -0.49 -7.09 -0.36 7.81e-12 Bipolar disorder and schizophrenia; LIHC cis rs2404602 0.647 rs11072636 chr15:77185786 A/G cg03037974 chr15:76606532 NA -0.61 -10.39 -0.49 3.61e-22 Blood metabolite levels; LIHC cis rs1865760 0.532 rs2006736 chr6:26086017 C/T cg18357526 chr6:26021779 HIST1H4A 0.45 6.55 0.33 2.08e-10 Height; LIHC cis rs9309711 0.666 rs11127429 chr2:3485224 T/G cg04359351 chr2:3481828 TTC15 0.29 6.04 0.31 3.97e-9 Neurofibrillary tangles; LIHC cis rs1577917 1.000 rs1018184 chr6:86648475 G/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.38 6.23 0.32 1.4e-9 Response to antipsychotic treatment; LIHC cis rs35146811 0.807 rs10228764 chr7:99608029 A/G cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.4 5.79 0.3 1.63e-8 Coronary artery disease; LIHC cis rs2115536 0.967 rs3826008 chr15:80189805 G/T cg00225070 chr15:80189496 MTHFS 0.66 11.21 0.52 4.84e-25 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs7903847 0.642 rs10882922 chr10:99158537 C/T cg20016023 chr10:99160130 RRP12 -0.42 -6.56 -0.33 1.95e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs826838 1.000 rs11168676 chr12:38977304 A/G cg26384229 chr12:38710491 ALG10B 0.9 11.9 0.54 1.43e-27 Heart rate; LIHC cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs9911578 1.000 rs11079365 chr17:56945430 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.84 10.18 0.48 1.94e-21 Mean platelet volume; LIHC cis rs10792665 0.575 rs10792655 chr11:82561661 T/C cg24227371 chr11:82718527 RAB30 -0.26 -6.29 -0.32 9.45e-10 Obesity-related traits; LIHC cis rs933688 1.000 rs11948075 chr5:90680579 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.6 0.67 8.33e-46 Smoking behavior; LIHC cis rs4919087 1.000 rs7078288 chr10:99086361 C/T cg25902810 chr10:99078978 FRAT1 -0.67 -10.02 -0.48 6.79e-21 Monocyte count; LIHC cis rs12142240 0.698 rs17357621 chr1:46807697 C/T cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs11676348 0.774 rs11683524 chr2:218984604 G/A cg00012203 chr2:219082015 ARPC2 -0.46 -5.95 -0.31 6.69e-9 Ulcerative colitis; LIHC cis rs798554 0.757 rs1182185 chr7:2872233 A/G cg13628971 chr7:2884303 GNA12 0.52 7.19 0.36 4.03e-12 Height; LIHC cis rs7412746 0.658 rs12097963 chr1:150870450 T/C cg18016565 chr1:150552671 MCL1 0.51 9.75 0.47 5.67e-20 Melanoma; LIHC cis rs12079745 0.793 rs79758658 chr1:169387286 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.78 -6.98 -0.35 1.51e-11 QT interval; LIHC cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.03 10.28 0.49 8.8e-22 Alzheimer's disease; LIHC cis rs35362007 0.530 rs10484053 chr14:96011645 C/T cg02940042 chr14:96000874 GLRX5;SNHG10;SCARNA13 0.74 6.33 0.32 7.53e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs7246657 0.882 rs6508716 chr19:37819010 T/C cg24637308 chr11:6592297 DNHD1 0.44 6.17 0.32 1.98e-9 Coronary artery calcification; LIHC cis rs941408 1.000 rs1640271 chr19:2799979 C/T cg06609049 chr19:2785107 THOP1 0.52 9.24 0.45 2.73e-18 Total cholesterol levels; LIHC cis rs72627123 0.656 rs4646864 chr14:74526703 G/A cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 5.78 0.3 1.69e-8 Morning vs. evening chronotype; LIHC cis rs9916302 0.851 rs12947620 chr17:37605364 T/C cg07936489 chr17:37558343 FBXL20 -0.85 -13.69 -0.6 2.49e-34 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27507545 chr10:103880405 LDB1 0.47 6.79 0.34 4.84e-11 Pancreatic cancer; LIHC cis rs2070488 1.000 rs17733640 chr3:38446742 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.63 0.65 6.05e-42 Electrocardiographic conduction measures; LIHC cis rs7512552 0.839 rs1097070 chr1:150332955 A/T cg15654264 chr1:150340011 RPRD2 0.69 11.33 0.52 1.78e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2439831 1.000 rs2444250 chr15:43785051 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.64 9.01 0.44 1.47e-17 Lung cancer in ever smokers; LIHC cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.68 0.46 9.54e-20 Platelet count; LIHC cis rs10870270 0.957 rs10870307 chr10:133780610 T/C cg17892150 chr10:133769511 PPP2R2D -0.68 -12.74 -0.57 1.09e-30 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs12220238 0.908 rs11000937 chr10:75998785 A/C cg19889307 chr10:75911429 ADK;AP3M1 0.66 6.87 0.35 3.08e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1003719 0.715 rs7282195 chr21:38508619 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.46e-25 Eye color traits; LIHC trans rs208515 0.525 rs10944869 chr6:66687576 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.8 0.43 6.96e-17 Exhaled nitric oxide levels; LIHC cis rs4423214 1.000 rs11546509 chr11:71162785 A/G cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC cis rs67311347 1.000 rs4973898 chr3:40459532 A/G cg24209194 chr3:40518798 ZNF619 -0.45 -6.63 -0.34 1.32e-10 Renal cell carcinoma; LIHC cis rs208520 1.000 rs72884025 chr6:66994185 T/C cg07460842 chr6:66804631 NA 0.68 7.32 0.37 1.8e-12 Exhaled nitric oxide output; LIHC cis rs4728302 0.869 rs6978170 chr7:133603838 C/T cg10665199 chr7:133106180 EXOC4 0.39 6.8 0.34 4.81e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs7937682 0.575 rs7114617 chr11:111768173 A/T cg09085632 chr11:111637200 PPP2R1B 0.94 13.48 0.59 1.64e-33 Primary sclerosing cholangitis; LIHC trans rs7668874 0.779 rs10005313 chr4:116807543 G/A cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC trans rs877282 0.700 rs816311 chr10:796490 C/A cg22713356 chr15:30763199 NA 1.21 11.49 0.53 4.56e-26 Uric acid levels; LIHC cis rs11675119 0.513 rs9752321 chr2:3494374 A/G cg15541040 chr2:3486749 NA -0.39 -5.72 -0.3 2.37e-8 Neurofibrillary tangles; LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.91 0.39 3.48e-14 Height; LIHC cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.88 7.96 0.4 2.52e-14 Platelet count; LIHC cis rs853679 0.517 rs6941992 chr6:28106141 T/C cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC trans rs1347297 0.614 rs7589679 chr2:179282437 T/C cg14011486 chr1:26737247 LIN28 0.65 10.32 0.49 6.42e-22 Alzheimer disease and age of onset; LIHC cis rs9911578 1.000 rs1631237 chr17:56734695 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs2730245 0.550 rs2709860 chr7:158651156 A/T cg23730037 chr7:158596552 ESYT2 -0.41 -6.44 -0.33 4.08e-10 Height; LIHC cis rs1005277 0.579 rs1780145 chr10:38537070 A/G cg25427524 chr10:38739819 LOC399744 -0.72 -14.15 -0.61 4.37e-36 Extrinsic epigenetic age acceleration; LIHC cis rs1799949 0.965 rs799910 chr17:41279561 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.77 0.3 1.77e-8 Menopause (age at onset); LIHC cis rs8108269 1.000 rs8104845 chr19:46161326 A/G cg13320842 chr19:46175254 GIPR 0.43 8.04 0.4 1.48e-14 Type 2 diabetes; LIHC cis rs1348850 0.914 rs7565022 chr2:178320222 A/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.84 13.13 0.58 3.68e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2274273 0.967 rs10147667 chr14:55570849 C/T cg01864836 chr14:55583639 NA 0.36 6.37 0.33 6.21e-10 Protein biomarker; LIHC cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg25072359 chr17:41440525 NA 0.37 5.99 0.31 5.46e-9 Menopause (age at onset); LIHC cis rs2070488 0.804 rs7646429 chr3:38467713 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.32 0.55 3.98e-29 Electrocardiographic conduction measures; LIHC cis rs7589728 0.563 rs75606549 chr2:88466069 T/C cg07952391 chr2:88470173 THNSL2 0.8 7.6 0.38 2.86e-13 Plasma clusterin levels; LIHC cis rs6089584 0.586 rs6089606 chr20:60586045 G/A cg06108461 chr20:60628389 TAF4 -0.52 -6.78 -0.34 5.15e-11 Body mass index; LIHC cis rs748404 0.660 rs690446 chr15:43761264 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 7.3 0.37 2.01e-12 Lung cancer; LIHC cis rs4718428 0.705 rs11028 chr7:66276217 T/C cg12165864 chr7:66369176 NA -0.46 -6.64 -0.34 1.23e-10 Corneal structure; LIHC trans rs2727020 0.729 rs1917325 chr11:49370004 G/A cg15704280 chr7:45808275 SEPT13 -0.93 -17.74 -0.69 2.13e-50 Coronary artery disease; LIHC cis rs35146811 1.000 rs35146811 chr7:99720994 A/C cg22906224 chr7:99728672 NA 0.42 5.98 0.31 5.61e-9 Coronary artery disease; LIHC cis rs7552404 0.727 rs12122939 chr1:76276353 T/C cg10523679 chr1:76189770 ACADM 0.58 7.19 0.36 4.13e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1941023 0.606 rs3825020 chr11:60184191 G/A cg08716584 chr11:60157161 MS4A7 -0.32 -7.07 -0.36 8.52e-12 Congenital heart disease (maternal effect); LIHC cis rs2281845 0.965 rs3738262 chr1:201083343 A/G cg24849736 chr1:201084428 NA -0.4 -8.2 -0.41 4.9e-15 Permanent tooth development; LIHC cis rs17685 0.753 rs1639609 chr7:75683581 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.55 -0.38 3.98e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12980942 0.872 rs12976536 chr19:41799886 T/A cg25627403 chr19:41769009 HNRNPUL1 0.57 6.88 0.35 2.82e-11 Coronary artery disease; LIHC cis rs9916302 0.851 rs4794810 chr17:37603774 T/C cg00129232 chr17:37814104 STARD3 -0.42 -6.68 -0.34 9.46e-11 Glomerular filtration rate (creatinine); LIHC cis rs875971 0.545 rs11767262 chr7:65767224 T/A cg11764359 chr7:65958608 NA 0.58 8.21 0.41 4.56e-15 Aortic root size; LIHC cis rs72627123 0.656 rs117145347 chr14:74564164 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.86 8.36 0.41 1.65e-15 Morning vs. evening chronotype; LIHC cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg09060608 chr5:178986726 RUFY1 0.39 5.93 0.31 7.22e-9 Lung cancer; LIHC cis rs2976388 0.647 rs2244163 chr8:143784500 T/G cg06565975 chr8:143823917 SLURP1 0.34 6.39 0.33 5.57e-10 Urinary tract infection frequency; LIHC cis rs3096299 0.802 rs3102336 chr16:89442006 C/T cg01788221 chr16:89496183 ANKRD11 -0.43 -6.76 -0.34 5.79e-11 Multiple myeloma (IgH translocation); LIHC trans rs62458065 0.513 rs787216 chr7:32578891 G/A cg00845942 chr12:64062724 DPY19L2 -0.56 -6.03 -0.31 4.17e-9 Metabolite levels (HVA/MHPG ratio); LIHC trans rs2727020 0.595 rs11040416 chr11:49566429 C/T cg03929089 chr4:120376271 NA -0.9 -18.07 -0.7 1.01e-51 Coronary artery disease; LIHC cis rs8114671 0.562 rs4911449 chr20:33512236 T/G cg07148914 chr20:33460835 GGT7 0.65 9.86 0.47 2.42e-20 Height; LIHC cis rs2153535 0.580 rs9393023 chr6:8469994 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs477692 0.699 rs471390 chr10:131382825 A/G cg05714579 chr10:131428358 MGMT -0.42 -6.81 -0.35 4.28e-11 Response to temozolomide; LIHC cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg08888203 chr3:10149979 C3orf24 0.57 6.49 0.33 3.06e-10 Alzheimer's disease; LIHC cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg06238570 chr21:40685208 BRWD1 -0.39 -6.15 -0.32 2.14e-9 Menarche (age at onset); LIHC trans rs2243480 1.000 rs12698509 chr7:65418876 C/T cg10756647 chr7:56101905 PSPH 1.09 13.45 0.59 2.13e-33 Diabetic kidney disease; LIHC cis rs7677751 0.767 rs6832597 chr4:55076237 C/A cg17187183 chr4:55093834 PDGFRA 0.58 7.49 0.38 5.82e-13 Corneal astigmatism; LIHC trans rs2262909 0.962 rs73021832 chr19:22316144 G/C cg05197062 chr11:11642011 GALNTL4 0.46 6.72 0.34 7.65e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg16262614 chr3:133464971 TF 0.28 6.23 0.32 1.34e-9 Iron status biomarkers; LIHC cis rs1451375 0.572 rs3807558 chr7:50571022 A/G cg14593290 chr7:50529359 DDC -0.61 -9.94 -0.47 1.31e-20 Malaria; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg27615432 chr3:150264278 SERP1;EIF2A -0.43 -6.13 -0.31 2.39e-9 Alopecia areata; LIHC cis rs79976124 0.800 rs6918860 chr6:66637741 G/C cg07460842 chr6:66804631 NA 0.67 7.23 0.36 3.18e-12 Type 2 diabetes; LIHC cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg05665937 chr4:1216051 CTBP1 0.44 5.81 0.3 1.44e-8 Obesity-related traits; LIHC cis rs12478296 0.792 rs3924263 chr2:243005167 A/C cg06360820 chr2:242988706 NA -0.82 -12.26 -0.55 6.88e-29 Obesity-related traits; LIHC cis rs748404 0.697 rs475227 chr15:43546446 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.42 6.47 0.33 3.36e-10 Lung cancer; LIHC cis rs12101261 0.580 rs8003515 chr14:81446242 G/C cg06600135 chr14:81408086 NA 0.44 7.78 0.39 8.49e-14 Graves' disease; LIHC cis rs12477438 0.501 rs11683188 chr2:99724512 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 13.91 0.6 3.47e-35 Chronic sinus infection; LIHC cis rs7520050 0.966 rs6701614 chr1:46309420 G/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs16828019 0.852 rs11209576 chr1:41586029 T/C cg03387723 chr1:41708464 SCMH1 -0.42 -6.93 -0.35 2.07e-11 Intelligence (multi-trait analysis); LIHC cis rs798766 0.830 rs8389 chr4:1746844 A/T cg21231739 chr4:1642635 FAM53A -0.37 -6.03 -0.31 4.21e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs57590327 0.503 rs7618973 chr3:81619588 C/T cg07356753 chr3:81810745 GBE1 0.54 8.36 0.41 1.62e-15 Extraversion; LIHC cis rs1005277 0.579 rs2504143 chr10:38383706 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08289482 chr15:59969074 BNIP2 0.42 6.54 0.33 2.23e-10 Hepatitis; LIHC cis rs7000551 0.751 rs2449338 chr8:22369232 A/G cg12081754 chr8:22256438 SLC39A14 0.42 6.64 0.34 1.24e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg04267008 chr7:1944627 MAD1L1 -0.7 -11.59 -0.53 2e-26 Bipolar disorder and schizophrenia; LIHC cis rs875971 1.000 rs1167612 chr7:65567976 C/A cg11764359 chr7:65958608 NA -0.87 -14.92 -0.63 4.04e-39 Aortic root size; LIHC trans rs4718428 0.705 rs13231140 chr7:66361618 C/G cg10756647 chr7:56101905 PSPH 0.63 8.62 0.42 2.51e-16 Corneal structure; LIHC cis rs3018712 0.532 rs2513289 chr11:68419655 A/C cg16797656 chr11:68205561 LRP5 -0.44 -5.79 -0.3 1.56e-8 Total body bone mineral density; LIHC cis rs2067615 0.524 rs7959062 chr12:107107334 G/T cg15890332 chr12:107067104 RFX4 0.27 6.38 0.33 5.68e-10 Heart rate; LIHC trans rs2727020 0.729 rs2299650 chr11:49174007 A/C cg15704280 chr7:45808275 SEPT13 -0.88 -16.44 -0.66 3.62e-45 Coronary artery disease; LIHC cis rs2153535 0.541 rs9505456 chr6:8479001 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs9486719 1.000 rs2263192 chr6:96873037 C/G cg06623918 chr6:96969491 KIAA0776 0.73 7.18 0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs9783347 0.754 rs4757637 chr11:18307575 G/T cg15585147 chr11:18324498 HPS5 0.39 6.5 0.33 2.77e-10 Pancreatic cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21625563 chr22:39152448 UNC84B 0.44 6.43 0.33 4.31e-10 Lung function (FEV1/FVC); LIHC cis rs10078 0.559 rs2671891 chr5:456386 A/G cg24955955 chr5:415729 AHRR 0.6 11.17 0.52 6.72e-25 Fat distribution (HIV); LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg02993280 chr1:107599747 PRMT6 -0.64 -10.16 -0.48 2.28e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6835098 0.924 rs1991727 chr4:174163169 A/G cg27433088 chr4:174089019 GALNT7 0.35 5.99 0.31 5.2e-9 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs10911232 0.507 rs4642853 chr1:182996242 C/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.14 0.48 2.62e-21 Hypertriglyceridemia; LIHC cis rs7614311 0.731 rs73117087 chr3:63948696 A/G cg22134162 chr3:63841271 THOC7 -0.54 -6.08 -0.31 3.13e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs6461049 0.765 rs1476887 chr7:2151633 T/C cg04267008 chr7:1944627 MAD1L1 -0.47 -7.18 -0.36 4.31e-12 Schizophrenia; LIHC cis rs2404602 0.647 rs10152247 chr15:76942252 T/G cg03037974 chr15:76606532 NA -0.61 -10.24 -0.48 1.21e-21 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03480210 chr2:39103037 DHX57;MORN2 -0.49 -6.41 -0.33 4.96e-10 Lung function (FEV1/FVC); LIHC cis rs317689 0.690 rs604168 chr12:69671158 C/T cg22834771 chr12:69754056 YEATS4 -0.4 -6.06 -0.31 3.63e-9 Response to diuretic therapy; LIHC cis rs7172677 1.000 rs4479194 chr15:75422131 C/T cg09165964 chr15:75287851 SCAMP5 -0.43 -5.94 -0.31 6.95e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs735396 0.965 rs2257962 chr12:121445808 T/C cg02403541 chr12:121454288 C12orf43 0.47 8.27 0.41 3.11e-15 N-glycan levels; LIHC trans rs1814175 0.626 rs1722008 chr11:49897676 A/T cg18944383 chr4:111397179 ENPEP 0.28 7.22 0.36 3.38e-12 Height; LIHC cis rs2797160 0.967 rs4897151 chr6:125993202 T/G cg05901451 chr6:126070800 HEY2 -0.4 -6.77 -0.34 5.66e-11 Endometrial cancer; LIHC cis rs7771547 0.542 rs597153 chr6:36395997 C/T cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Platelet distribution width; LIHC cis rs11077998 0.967 rs4789796 chr17:80521135 T/C cg10255544 chr17:80519551 FOXK2 0.5 8.92 0.43 2.87e-17 Reticulocyte fraction of red cells; LIHC cis rs7820838 0.611 rs6996957 chr8:32306984 A/G cg16623836 chr8:32453385 NRG1 0.37 6.25 0.32 1.22e-9 Post bronchodilator FEV1/FVC ratio in COPD;Lung cancer; LIHC cis rs8017423 0.647 rs4904680 chr14:90822075 C/T cg04374321 chr14:90722782 PSMC1 -0.49 -7.29 -0.37 2.13e-12 Mortality in heart failure; LIHC cis rs2295359 1.000 rs11465754 chr1:67631431 A/G cg12940439 chr1:67600707 NA 0.38 6.84 0.35 3.65e-11 Psoriasis; LIHC cis rs7959452 0.640 rs12370042 chr12:69692420 C/G cg14784868 chr12:69753453 YEATS4 0.88 16.99 0.68 2.24e-47 Blood protein levels; LIHC cis rs6788895 1.000 rs2014279 chr3:150487945 G/T cg09723797 chr3:150481914 SIAH2 0.9 13.5 0.59 1.33e-33 Breast cancer; LIHC cis rs929354 0.772 rs7778193 chr7:156980087 C/T cg17757837 chr7:157058334 UBE3C 0.73 11.86 0.54 2.12e-27 Body mass index; LIHC cis rs7927592 0.673 rs2510392 chr11:68394457 C/G cg20283391 chr11:68216788 NA -0.39 -6.15 -0.32 2.2e-9 Total body bone mineral density; LIHC cis rs9633740 1.000 rs1902660 chr10:82263683 G/C cg01528321 chr10:82214614 TSPAN14 0.93 11.65 0.53 1.17e-26 Post bronchodilator FEV1; LIHC cis rs798554 0.567 rs2527695 chr7:2858267 T/G cg19717773 chr7:2847554 GNA12 -0.42 -7.45 -0.37 7.62e-13 Height; LIHC cis rs600806 0.778 rs4970761 chr1:109995398 C/T cg02415029 chr1:110025642 ATXN7L2 -0.5 -6.32 -0.32 8.08e-10 Intelligence (multi-trait analysis); LIHC trans rs4718428 0.705 rs10267335 chr7:66403220 G/T cg10756647 chr7:56101905 PSPH 0.62 8.64 0.42 2.11e-16 Corneal structure; LIHC cis rs1577917 1.000 rs6940458 chr6:86644992 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.6 -0.5 6.93e-23 Response to antipsychotic treatment; LIHC cis rs10131894 0.635 rs174997 chr14:75434806 G/A cg08847533 chr14:75593920 NEK9 -0.83 -16.32 -0.66 1.14e-44 Coronary artery disease; LIHC cis rs2839186 0.967 rs2839191 chr21:47695395 C/G cg05896524 chr21:47604654 C21orf56 0.44 6.55 0.33 2.08e-10 Testicular germ cell tumor; LIHC cis rs7258465 0.965 rs7253990 chr19:18604085 C/G cg10790698 chr19:18539756 SSBP4 -0.36 -7.54 -0.38 4.22e-13 Breast cancer; LIHC cis rs9399137 0.507 rs4594969 chr6:135285586 A/T cg24558204 chr6:135376177 HBS1L 0.58 9.81 0.47 3.42e-20 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs7264396 0.790 rs8125090 chr20:34360015 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -10.66 -0.5 4.38e-23 Total cholesterol levels; LIHC cis rs68170813 0.559 rs75932578 chr7:106844694 C/T cg02696742 chr7:106810147 HBP1 -0.55 -6.34 -0.32 7.19e-10 Coronary artery disease; LIHC cis rs1387259 0.723 rs2732488 chr12:48771444 G/A cg21466736 chr12:48725269 NA -0.62 -9.16 -0.44 4.73e-18 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.81 0.62 1.13e-38 Prudent dietary pattern; LIHC cis rs11924390 0.749 rs822363 chr3:186452991 C/G cg12454167 chr3:186435060 KNG1 0.32 7.68 0.38 1.74e-13 Adiponectin levels; LIHC cis rs9916302 0.904 rs10432031 chr17:37397852 G/A cg00129232 chr17:37814104 STARD3 -0.4 -6.38 -0.33 5.87e-10 Glomerular filtration rate (creatinine); LIHC cis rs9430161 0.644 rs34365965 chr1:11034442 G/A cg27631724 chr1:11040367 C1orf127 0.36 6.68 0.34 9.79e-11 Ewing sarcoma; LIHC cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.16 18.04 0.7 1.36e-51 Gut microbiome composition (summer); LIHC cis rs2067615 0.560 rs2044304 chr12:107184363 T/G cg15890332 chr12:107067104 RFX4 0.26 6.09 0.31 3.01e-9 Heart rate; LIHC cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg24675658 chr1:53192096 ZYG11B 0.57 9.01 0.44 1.53e-17 Monocyte count; LIHC cis rs763121 0.853 rs5750633 chr22:38993467 A/G cg21395723 chr22:39101663 GTPBP1 0.41 6.97 0.35 1.68e-11 Menopause (age at onset); LIHC cis rs10751667 0.961 rs7396670 chr11:929269 A/G cg10932868 chr11:921992 NA 0.35 6.56 0.33 1.96e-10 Alzheimer's disease (late onset); LIHC cis rs939574 1.000 rs56927225 chr2:220100922 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.02 10.72 0.5 2.59e-23 Platelet distribution width; LIHC cis rs2997447 0.723 rs868551 chr1:26475521 C/T cg19633962 chr1:26362018 EXTL1 0.58 7.02 0.35 1.2e-11 QRS complex (12-leadsum); LIHC cis rs7582180 0.602 rs7585582 chr2:100998030 G/C cg14675211 chr2:100938903 LONRF2 0.56 8.23 0.41 4.08e-15 Intelligence (multi-trait analysis); LIHC cis rs8017423 0.647 rs1958346 chr14:90824011 G/T cg04374321 chr14:90722782 PSMC1 -0.49 -7.26 -0.37 2.56e-12 Mortality in heart failure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07447193 chr4:151935870 LRBA 0.51 7.65 0.38 2.07e-13 Cognitive function; LIHC cis rs1552244 0.572 rs6783705 chr3:10164783 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.62 -0.5 5.78e-23 Alzheimer's disease; LIHC cis rs7412746 0.611 rs2864873 chr1:150814174 A/G cg17724175 chr1:150552817 MCL1 0.46 8.96 0.44 2.06e-17 Melanoma; LIHC cis rs262150 0.819 rs6956589 chr7:158769301 C/T cg27247782 chr7:158767135 NA -0.29 -5.93 -0.31 7.42e-9 Facial morphology (factor 20); LIHC cis rs12291225 0.535 rs11023203 chr11:14409815 G/A cg19336497 chr11:14380999 RRAS2 -0.55 -10.37 -0.49 4.28e-22 Sense of smell; LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.5 -6.2 -0.32 1.66e-9 Diastolic blood pressure; LIHC cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.63 0.5 5.28e-23 Vitiligo; LIHC cis rs3018712 0.590 rs4930584 chr11:68411296 T/C cg16797656 chr11:68205561 LRP5 -0.44 -5.83 -0.3 1.28e-8 Total body bone mineral density; LIHC cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.41 -0.37 9.75e-13 Initial pursuit acceleration; LIHC cis rs11098499 0.554 rs2175381 chr4:120265967 T/C cg09307838 chr4:120376055 NA 0.63 9.84 0.47 2.86e-20 Corneal astigmatism; LIHC cis rs7772486 0.686 rs9376961 chr6:146048737 C/T cg05347473 chr6:146136440 FBXO30 0.36 5.8 0.3 1.48e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2032447 0.613 rs6456708 chr6:26032847 G/C cg17691542 chr6:26056736 HIST1H1C 0.44 6.09 0.31 3.06e-9 Intelligence (multi-trait analysis); LIHC cis rs739401 0.527 rs423236 chr11:3065916 C/T cg25174290 chr11:3078921 CARS 0.67 10.12 0.48 3.25e-21 Longevity; LIHC cis rs72781680 0.715 rs72796332 chr2:24142060 G/A cg08917208 chr2:24149416 ATAD2B 0.64 6.44 0.33 4.1e-10 Lymphocyte counts; LIHC cis rs1348850 0.567 rs12994392 chr2:178536640 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.27 0.41 3.05e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4919087 1.000 rs10786327 chr10:99071408 C/T cg25902810 chr10:99078978 FRAT1 0.7 10.9 0.51 6.1e-24 Monocyte count; LIHC cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg07424592 chr7:64974309 NA -0.79 -9.28 -0.45 1.95e-18 Diabetic kidney disease; LIHC trans rs9356009 0.649 rs9356100 chr6:158299952 C/T cg16165903 chr3:32023351 ZNF860;OSBPL10 0.65 6.35 0.32 6.86e-10 Lipoprotein (a) - cholesterol levels; LIHC cis rs10752881 0.743 rs10737244 chr1:183098417 G/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Colorectal cancer; LIHC cis rs909002 0.886 rs11807225 chr1:32083193 G/C cg13919466 chr1:32135498 COL16A1 -0.31 -6.02 -0.31 4.54e-9 Intelligence (multi-trait analysis); LIHC cis rs7493 0.755 rs34774523 chr7:94962142 G/A cg21856205 chr7:94953877 PON1 -0.48 -6.18 -0.32 1.85e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.25 -0.45 2.55e-18 Bipolar disorder; LIHC cis rs6502050 0.835 rs35192339 chr17:80119106 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs72781680 0.898 rs7563564 chr2:23993404 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.62 0.38 2.45e-13 Lymphocyte counts; LIHC cis rs4808199 0.901 rs11669516 chr19:19532682 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.42 5.96 0.31 6.23e-9 Nonalcoholic fatty liver disease; LIHC cis rs2033908 0.502 rs12361858 chr11:12857064 C/T cg25843174 chr11:12811716 TEAD1 -0.33 -7.37 -0.37 1.3e-12 Sitting height ratio; LIHC cis rs1005277 0.502 rs2800484 chr10:38542415 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.43 -6.35 -0.32 6.86e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg03517284 chr6:25882590 NA -0.65 -8.08 -0.4 1.12e-14 Intelligence (multi-trait analysis); LIHC cis rs3820068 0.603 rs6660234 chr1:15962590 T/C cg17385448 chr1:15911702 AGMAT 0.34 5.84 0.3 1.21e-8 Systolic blood pressure; LIHC cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg18404041 chr3:52824283 ITIH1 -0.58 -9.8 -0.47 3.81e-20 Bipolar disorder; LIHC cis rs2074585 0.839 rs11638780 chr15:91041896 G/T cg22089800 chr15:90895588 ZNF774 -0.59 -8.09 -0.4 1.08e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs1757171 0.504 rs11969056 chr6:37484285 C/T cg01843034 chr6:37503916 NA -0.48 -8.17 -0.4 6.16e-15 Cognitive performance; LIHC cis rs7107174 0.688 rs10899501 chr11:78131408 C/T cg02023728 chr11:77925099 USP35 0.42 7.42 0.37 9.39e-13 Testicular germ cell tumor; LIHC cis rs7927771 0.931 rs12361256 chr11:47910823 A/C cg20135002 chr11:47629003 NA -0.5 -8.47 -0.42 7.36e-16 Subjective well-being; LIHC cis rs2404602 0.647 rs2404604 chr15:76991105 A/G cg23625390 chr15:77176239 SCAPER -0.53 -8.9 -0.43 3.22e-17 Blood metabolite levels; LIHC cis rs7312933 0.558 rs1796394 chr12:42826359 G/A cg17420585 chr12:42539391 GXYLT1 0.35 5.71 0.3 2.39e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs67460515 0.892 rs6780536 chr3:161058726 T/C cg03342759 chr3:160939853 NMD3 -0.57 -8.55 -0.42 4.27e-16 Parkinson's disease; LIHC cis rs1005277 0.579 rs2800485 chr10:38542588 G/A cg18963800 chr10:38644991 HSD17B7P2 -0.43 -6.35 -0.32 6.86e-10 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.72 11.47 0.53 5.52e-26 Prudent dietary pattern; LIHC cis rs1348850 0.872 rs13004955 chr2:178398923 A/T cg02961200 chr2:178257176 LOC100130691;AGPS -0.86 -13.25 -0.58 1.28e-32 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg00280220 chr17:61926910 NA 0.44 7.07 0.36 8.7e-12 Prudent dietary pattern; LIHC cis rs2795502 1.000 rs2795497 chr10:43339475 C/A cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs1062177 0.547 rs2915818 chr5:151115290 T/A cg00977110 chr5:151150581 G3BP1 -0.53 -6.88 -0.35 2.78e-11 Preschool internalizing problems; LIHC cis rs796364 0.865 rs769948 chr2:200728475 C/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.73 8.52 0.42 5.06e-16 Schizophrenia; LIHC cis rs16854884 0.657 rs13086088 chr3:143723942 G/A cg06585982 chr3:143692056 C3orf58 0.54 7.06 0.36 9.48e-12 Economic and political preferences (feminism/equality); LIHC cis rs17685 0.753 rs1637044 chr7:75703744 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10607599 chr11:120382422 NA -0.42 -6.2 -0.32 1.65e-9 Cognitive function; LIHC cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04441191 chr3:48130393 MAP4 0.42 6.46 0.33 3.58e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg10896456 chr17:42255109 ASB16;C17orf65 0.52 9.46 0.46 5.22e-19 Total body bone mineral density; LIHC cis rs7044106 0.537 rs10739573 chr9:123489818 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 9.5 0.46 3.71e-19 Hip circumference adjusted for BMI; LIHC cis rs116095464 0.558 rs28418643 chr5:240859 A/G cg22857025 chr5:266934 NA -1.48 -18.13 -0.7 5.78e-52 Breast cancer; LIHC cis rs796364 0.951 rs769952 chr2:200734368 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.73 8.52 0.42 5.06e-16 Schizophrenia; LIHC cis rs35306767 0.904 rs10904584 chr10:983747 A/T cg26597838 chr10:835615 NA 0.95 11.15 0.52 7.63e-25 Eosinophil percentage of granulocytes; LIHC cis rs3815700 1.000 rs10407204 chr19:33097353 C/T cg02997394 chr19:33096574 ANKRD27 0.73 9.57 0.46 2.15e-19 Eosinophilic esophagitis; LIHC cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg18306943 chr3:40428807 ENTPD3 0.36 6.16 0.32 2.09e-9 Renal cell carcinoma; LIHC cis rs2731664 0.792 rs2731662 chr5:176872494 C/T cg23176889 chr5:176863531 GRK6 0.72 12.81 0.57 5.98e-31 Intelligence (multi-trait analysis); LIHC trans rs2832191 0.703 rs2853827 chr21:30443596 T/C cg14791747 chr16:20752902 THUMPD1 -0.47 -6.48 -0.33 3.17e-10 Dental caries; LIHC cis rs9590974 0.600 rs60929536 chr13:47226506 T/C cg04092803 chr13:47240378 LRCH1 0.29 6.13 0.31 2.38e-9 PR segment; LIHC cis rs6942756 0.955 rs9641849 chr7:128899238 C/T cg02491457 chr7:128862824 NA -0.73 -11.88 -0.54 1.73e-27 White matter hyperintensity burden; LIHC cis rs3892630 0.620 rs10413279 chr19:33182746 A/G cg22980127 chr19:33182716 NUDT19 1.15 19.06 0.72 1.07e-55 Red blood cell traits; LIHC cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg07677032 chr17:61819896 STRADA 0.43 6.33 0.32 7.7e-10 Prudent dietary pattern; LIHC cis rs16854884 0.657 rs7637912 chr3:143749777 G/A cg06585982 chr3:143692056 C3orf58 0.55 7.21 0.36 3.58e-12 Economic and political preferences (feminism/equality); LIHC cis rs801193 1.000 rs6975195 chr7:66124774 T/A cg18876405 chr7:65276391 NA -0.43 -7.4 -0.37 1.07e-12 Aortic root size; LIHC cis rs2404602 0.692 rs56193230 chr15:76934472 C/T cg03037974 chr15:76606532 NA 0.74 14.45 0.62 2.79e-37 Blood metabolite levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13537801 chr17:79663039 HGS -0.39 -6.45 -0.33 3.79e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6582630 0.519 rs12366667 chr12:38332632 C/T cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.57e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs1707322 0.827 rs6694302 chr1:46245645 A/T cg03146154 chr1:46216737 IPP 0.53 8.72 0.43 1.2e-16 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs72627123 0.737 rs77361581 chr14:74465290 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.89 8.6 0.42 2.96e-16 Morning vs. evening chronotype; LIHC cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg13271783 chr10:134563150 INPP5A -0.6 -7.21 -0.36 3.69e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17102423 0.689 rs7158239 chr14:65520616 G/A cg16583315 chr14:65563665 MAX -0.37 -7.12 -0.36 6.58e-12 Obesity-related traits; LIHC cis rs17685 0.753 rs4728586 chr7:75802869 T/C cg04610667 chr7:75704037 NA -0.35 -6.18 -0.32 1.86e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs903552 0.932 rs1587108 chr15:102006825 G/A cg00659931 chr15:102010125 PCSK6 -0.46 -6.18 -0.32 1.84e-9 Diabetic kidney disease; LIHC cis rs11229555 1.000 rs2276153 chr11:58407740 C/G cg15696309 chr11:58395628 NA -0.73 -8.97 -0.44 2.02e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg03390569 chr2:54013802 LOC100302652;ASB3;ERLEC1 -0.56 -6.22 -0.32 1.45e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs12950390 0.893 rs4794110 chr17:45847230 A/G cg03474202 chr17:45855739 NA -0.32 -6.11 -0.31 2.78e-9 IgG glycosylation; LIHC cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg07061783 chr6:25882402 NA -0.44 -6.08 -0.31 3.26e-9 Blood metabolite levels; LIHC cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg24675658 chr1:53192096 ZYG11B 0.64 10.32 0.49 6.29e-22 Monocyte count; LIHC cis rs28735056 0.935 rs11662267 chr18:77641902 C/G cg20368463 chr18:77673604 PQLC1 -0.35 -5.94 -0.31 7.13e-9 Schizophrenia; LIHC trans rs2727020 0.595 rs10839286 chr11:49497063 C/A cg03929089 chr4:120376271 NA -0.89 -17.96 -0.7 2.75e-51 Coronary artery disease; LIHC cis rs7267979 0.866 rs437635 chr20:25456888 A/G cg24626310 chr20:25276739 ABHD12;PYGB 0.45 6.77 0.34 5.56e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs77669868 0.866 rs2735195 chr11:114051192 A/G cg01914181 chr11:114070210 ZBTB16 -0.58 -7.65 -0.38 2.08e-13 Monocyte percentage of white cells; LIHC cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg03264133 chr6:25882463 NA 0.47 6.79 0.34 5.13e-11 Blood metabolite levels; LIHC cis rs9858542 0.953 rs6446264 chr3:49417243 C/A cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs10892173 0.566 rs10892174 chr11:117672565 A/C cg21640587 chr11:117668038 DSCAML1 0.53 6.6 0.34 1.55e-10 Myopia; LIHC cis rs7246657 0.943 rs7255952 chr19:37988797 A/G cg23950597 chr19:37808831 NA -0.48 -6.22 -0.32 1.42e-9 Coronary artery calcification; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21211866 chr9:35111727 KIAA1539 0.47 7.08 0.36 8.05e-12 Pancreatic cancer; LIHC cis rs17818399 0.890 rs34544165 chr2:46836906 A/G cg02822958 chr2:46747628 ATP6V1E2 0.48 7.51 0.38 5.32e-13 Height; LIHC cis rs16854884 0.582 rs35211123 chr3:143640171 A/T cg06585982 chr3:143692056 C3orf58 0.63 8.73 0.43 1.15e-16 Economic and political preferences (feminism/equality); LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg05484376 chr2:27715224 FNDC4 0.37 6.22 0.32 1.44e-9 Total body bone mineral density; LIHC cis rs7927592 0.956 rs10896343 chr11:68317860 G/C cg20283391 chr11:68216788 NA -0.52 -7.88 -0.39 4.54e-14 Total body bone mineral density; LIHC cis rs2153535 0.546 rs1335640 chr6:8485325 A/C cg07606381 chr6:8435919 SLC35B3 0.8 12.02 0.54 5.36e-28 Motion sickness; LIHC cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg10802521 chr3:52805072 NEK4 -0.44 -7.48 -0.38 6.18e-13 Bipolar disorder; LIHC cis rs7618501 1.000 rs6775384 chr3:49853073 G/A cg24110177 chr3:50126178 RBM5 -0.48 -7.41 -0.37 1.02e-12 Intelligence (multi-trait analysis); LIHC cis rs9733 0.519 rs11807450 chr1:150677719 C/T cg17724175 chr1:150552817 MCL1 0.5 10.01 0.48 7.57e-21 Tonsillectomy; LIHC trans rs2727020 0.553 rs10839295 chr11:49527345 A/C cg03929089 chr4:120376271 NA -0.87 -16.84 -0.67 9.04e-47 Coronary artery disease; LIHC cis rs933688 0.941 rs2887007 chr5:90740531 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.85 18.08 0.7 9.07e-52 Smoking behavior; LIHC cis rs9296092 0.538 rs75082458 chr6:33524792 C/T cg13560919 chr6:33536144 NA -0.39 -6.32 -0.32 8.31e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs780094 0.544 rs780110 chr2:27685388 G/A cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.71 -0.3 2.45e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg02951883 chr7:2050386 MAD1L1 -0.54 -8.12 -0.4 8.7e-15 Bipolar disorder and schizophrenia; LIHC cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2204008 0.818 rs1589389 chr12:38416041 G/A cg26384229 chr12:38710491 ALG10B -0.58 -8.43 -0.41 9.67e-16 Bladder cancer; LIHC cis rs1639906 0.895 rs6972752 chr7:2196551 G/A cg22963979 chr7:1858916 MAD1L1 0.41 5.72 0.3 2.38e-8 Colonoscopy-negative controls vs population controls; LIHC trans rs116095464 0.510 rs7723883 chr5:270798 T/C cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs11758351 1.000 rs77961951 chr6:26186075 A/G cg01420254 chr6:26195488 NA 0.54 5.77 0.3 1.75e-8 Gout;Renal underexcretion gout; LIHC cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg21724239 chr8:58056113 NA 0.48 6.21 0.32 1.58e-9 Developmental language disorder (linguistic errors); LIHC cis rs1577917 0.518 rs6454482 chr6:86418188 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.46 9.27 0.45 2.09e-18 Response to antipsychotic treatment; LIHC cis rs9790314 1.000 rs336548 chr3:161058412 T/C cg04691961 chr3:161091175 C3orf57 -0.42 -6.64 -0.34 1.25e-10 Morning vs. evening chronotype; LIHC cis rs2334880 0.678 rs7186112 chr16:71840073 A/T cg06353428 chr16:71660113 MARVELD3 1.31 13.47 0.59 1.84e-33 Malaria; LIHC cis rs2191566 1.000 rs7253205 chr19:44503607 T/C cg20607764 chr19:44506953 ZNF230 -0.4 -6.22 -0.32 1.44e-9 Acute lymphoblastic leukemia (childhood); LIHC cis rs2576037 0.583 rs4890698 chr18:44489725 A/G cg19077165 chr18:44547161 KATNAL2 -0.47 -7.15 -0.36 5.41e-12 Personality dimensions; LIHC cis rs2279817 0.731 rs76970608 chr1:18010198 G/A cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.76 -0.39 9.68e-14 Neuroticism; LIHC cis rs7904368 1.000 rs7904368 chr10:16858587 C/T cg23933602 chr10:16859644 RSU1 0.6 6.18 0.32 1.85e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs67460515 0.563 rs35914913 chr3:160826561 A/G cg17135325 chr3:160939158 NMD3 0.55 7.78 0.39 8.89e-14 Parkinson's disease; LIHC trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg07332563 chr6:291687 DUSP22 -0.55 -7.71 -0.38 1.39e-13 Menopause (age at onset); LIHC cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg08048268 chr3:133502702 NA 0.42 6.31 0.32 8.72e-10 Iron status biomarkers; LIHC cis rs7503807 0.701 rs1485329 chr17:78643561 A/G cg09596252 chr17:78655493 RPTOR 0.38 6.39 0.33 5.49e-10 Obesity; LIHC cis rs4713118 0.513 rs183244 chr6:28031838 C/A cg16479474 chr6:28041457 NA 0.38 6.32 0.32 8.32e-10 Parkinson's disease; LIHC cis rs36051895 0.589 rs12682672 chr9:5187941 T/C cg02405213 chr9:5042618 JAK2 -0.67 -11.17 -0.52 6.68e-25 Pediatric autoimmune diseases; LIHC cis rs7635838 0.892 rs2880897 chr3:11494544 A/G cg00170343 chr3:11313890 ATG7 0.4 6.22 0.32 1.42e-9 HDL cholesterol; LIHC cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg09033563 chr22:24373618 LOC391322 -0.44 -5.89 -0.3 9.16e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618501 1.000 rs1491986 chr3:49739086 C/T cg24110177 chr3:50126178 RBM5 0.43 6.66 0.34 1.08e-10 Intelligence (multi-trait analysis); LIHC cis rs11958404 0.860 rs72818114 chr5:157440207 A/C cg05962755 chr5:157440814 NA 0.99 11.5 0.53 4.32e-26 IgG glycosylation; LIHC cis rs3008870 0.629 rs12742428 chr1:67426487 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.66 0.5 4.25e-23 Lymphocyte percentage of white cells; LIHC cis rs919433 0.927 rs7592748 chr2:198170688 G/A cg03934865 chr2:198174659 NA -0.57 -9.06 -0.44 1.04e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6964587 1.000 rs36120033 chr7:91679298 G/A cg17063962 chr7:91808500 NA 1.01 19.37 0.72 5.94e-57 Breast cancer; LIHC cis rs7520050 0.966 rs7550746 chr1:46351719 T/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.85 0.3 1.14e-8 Red blood cell count;Reticulocyte count; LIHC cis rs16854884 0.657 rs10513235 chr3:143698664 T/C cg06585982 chr3:143692056 C3orf58 0.57 7.53 0.38 4.44e-13 Economic and political preferences (feminism/equality); LIHC trans rs61931739 0.534 rs11053005 chr12:34091626 A/C cg26384229 chr12:38710491 ALG10B 0.49 6.83 0.35 3.89e-11 Morning vs. evening chronotype; LIHC cis rs7927592 0.913 rs7106010 chr11:68365212 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.24 -0.32 1.27e-9 Total body bone mineral density; LIHC cis rs36051895 0.623 rs10975033 chr9:5262567 C/T cg02405213 chr9:5042618 JAK2 -0.56 -9.41 -0.45 7.68e-19 Pediatric autoimmune diseases; LIHC cis rs9457247 0.967 rs387733 chr6:167409771 C/T cg23791538 chr6:167370224 RNASET2 0.66 10.98 0.51 3.27e-24 Crohn's disease; LIHC cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.52 -0.69 1.72e-49 Gut microbiome composition (summer); LIHC cis rs7552404 1.000 rs4559448 chr1:76203456 A/G cg22875332 chr1:76189707 ACADM 0.47 6.87 0.35 2.97e-11 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs9747201 1.000 rs4347682 chr17:80175591 A/G cg07393940 chr7:158741817 NA 0.54 6.25 0.32 1.21e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs17685 0.712 rs1637049 chr7:75729975 C/G cg01364799 chr7:75623366 TMEM120A -0.49 -7.4 -0.37 1.03e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9911578 1.000 rs2055779 chr17:57030561 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -8.85 -0.43 4.89e-17 Intelligence (multi-trait analysis); LIHC cis rs2710642 0.962 rs7557501 chr2:63086639 C/T cg17519650 chr2:63277830 OTX1 0.43 6.85 0.35 3.53e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs9467773 0.526 rs12199613 chr6:26367218 C/T cg09904177 chr6:26538194 HMGN4 -0.37 -5.79 -0.3 1.57e-8 Intelligence (multi-trait analysis); LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg03874509 chr1:107600012 PRMT6 -0.77 -12.17 -0.55 1.47e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs116095464 0.558 rs7715108 chr5:264661 A/G cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs28489187 0.643 rs997251 chr1:85845367 T/C cg16011679 chr1:85725395 C1orf52 0.46 5.86 0.3 1.08e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs2075371 1.000 rs1421486 chr7:133985196 T/C cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.82e-14 Mean platelet volume; LIHC cis rs12474201 0.928 rs13429704 chr2:46960329 G/T cg06386533 chr2:46925753 SOCS5 0.76 8.84 0.43 5.15e-17 Height; LIHC cis rs4638749 0.603 rs34153365 chr2:108846583 C/T cg25838818 chr2:108905173 SULT1C2 -0.39 -7.02 -0.35 1.2e-11 Blood pressure; LIHC cis rs4969178 0.965 rs8072632 chr17:76397830 T/C cg20026190 chr17:76395443 PGS1 0.46 7.29 0.37 2.11e-12 HDL cholesterol levels; LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg23131131 chr22:24373011 LOC391322 -0.73 -11.02 -0.51 2.19e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9814567 0.928 rs6768323 chr3:134268737 A/C cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2204008 0.805 rs11180825 chr12:38242916 G/T cg26384229 chr12:38710491 ALG10B 0.87 10.83 0.51 1.06e-23 Bladder cancer; LIHC cis rs6952808 0.636 rs6964522 chr7:1953523 C/T cg20295408 chr7:1910781 MAD1L1 -0.52 -7.57 -0.38 3.43e-13 Bipolar disorder and schizophrenia; LIHC cis rs2070488 0.965 rs9877282 chr3:38541452 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.92 -16.04 -0.66 1.47e-43 Electrocardiographic conduction measures; LIHC cis rs6933660 0.800 rs2046371 chr6:151754744 G/A cg14262678 chr6:151773367 RMND1;C6orf211 0.49 7.28 0.37 2.26e-12 Menarche (age at onset); LIHC cis rs5769707 0.967 rs17182154 chr22:49990470 A/G cg01652190 chr22:50026171 C22orf34 -0.29 -6.57 -0.33 1.9e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7131987 0.683 rs7954278 chr12:29459290 G/A cg12903224 chr12:29470962 FAR2 -0.39 -6.34 -0.32 7.41e-10 QT interval; LIHC cis rs17376456 0.877 rs10060462 chr5:93455073 C/T cg25358565 chr5:93447407 FAM172A 1.12 10.35 0.49 5.17e-22 Diabetic retinopathy; LIHC cis rs4845459 0.967 rs75567512 chr1:152587933 C/A cg20634798 chr1:152595351 LCE3A -0.3 -5.86 -0.3 1.1e-8 Psoriasis; LIHC cis rs509477 0.718 rs273357 chr18:32597237 G/T cg23791764 chr18:32556832 MAPRE2 0.44 5.88 0.3 9.81e-9 Cerebrospinal fluid AB1-42 levels; LIHC trans rs35110281 0.715 rs969060 chr21:45080852 T/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.5 6.66 0.34 1.08e-10 Mean corpuscular volume; LIHC cis rs9611565 0.525 rs9611548 chr22:41704143 G/T cg03806693 chr22:41940476 POLR3H -0.78 -8.74 -0.43 1.06e-16 Vitiligo; LIHC cis rs1707322 0.686 rs3014236 chr1:46091305 T/C cg24296786 chr1:45957014 TESK2 0.42 6.16 0.32 2.07e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg08888203 chr3:10149979 C3orf24 0.55 6.35 0.32 6.76e-10 Alzheimer's disease; LIHC cis rs4819052 0.679 rs4819053 chr21:46711357 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 -0.59 -9.3 -0.45 1.73e-18 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs360798 0.532 rs360797 chr2:62942840 C/T cg17519650 chr2:63277830 OTX1 -0.47 -6.98 -0.35 1.57e-11 Coronary artery disease; LIHC cis rs3784262 1.000 rs7170896 chr15:58252393 T/A cg12031962 chr15:58353849 ALDH1A2 -0.33 -6.47 -0.33 3.43e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6089829 0.925 rs11086152 chr20:61664656 T/C cg03213289 chr20:61660250 NA 0.5 8.85 0.43 4.93e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs12086130 0.656 rs12075888 chr1:51416823 C/T cg07174182 chr1:51127561 FAF1 -0.74 -7.94 -0.39 2.99e-14 Hip circumference adjusted for BMI;Hip circumference; LIHC cis rs10089 0.953 rs1432614 chr5:127416919 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.79 0.34 4.89e-11 Ileal carcinoids; LIHC cis rs6951245 0.935 rs11763765 chr7:1060510 C/T cg08132940 chr7:1081526 C7orf50 -0.76 -6.49 -0.33 3.02e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7264396 0.563 rs2425120 chr20:34324456 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.47e-16 Total cholesterol levels; LIHC cis rs3741798 1.000 rs61922025 chr12:12486263 G/A cg08615371 chr12:12503544 MANSC1 0.98 7.84 0.39 5.9e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs6570726 0.905 rs442435 chr6:145815559 C/T cg23711669 chr6:146136114 FBXO30 0.5 8.71 0.43 1.35e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs6570726 0.764 rs9386125 chr6:145911677 C/T cg23711669 chr6:146136114 FBXO30 0.7 11.65 0.53 1.22e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.525 rs9611549 chr22:41705909 C/G cg06634786 chr22:41940651 POLR3H -0.53 -6.26 -0.32 1.17e-9 Vitiligo; LIHC trans rs7618501 0.633 rs11925192 chr3:50038664 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.56 9.31 0.45 1.6e-18 Intelligence (multi-trait analysis); LIHC cis rs769267 0.895 rs2965183 chr19:19545696 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.03 0.31 4.17e-9 Tonsillectomy; LIHC cis rs600806 0.778 rs4970767 chr1:110015183 G/A cg23091122 chr1:110024289 SYPL2 -0.44 -6.09 -0.31 3.07e-9 Intelligence (multi-trait analysis); LIHC cis rs8141529 0.732 rs5762788 chr22:29174770 G/T cg02153584 chr22:29168773 CCDC117 0.53 8.51 0.42 5.61e-16 Lymphocyte counts; LIHC cis rs597539 0.617 rs669659 chr11:68635623 G/C cg04772025 chr11:68637568 NA 0.46 6.24 0.32 1.33e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg07061783 chr6:25882402 NA -0.47 -6.53 -0.33 2.38e-10 Blood metabolite levels; LIHC cis rs9790314 0.967 rs460165 chr3:161087710 G/A cg03342759 chr3:160939853 NMD3 -0.65 -7.61 -0.38 2.66e-13 Morning vs. evening chronotype; LIHC cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg13866156 chr1:1669148 SLC35E2 -0.69 -13.38 -0.59 3.85e-33 Body mass index; LIHC cis rs922107 0.738 rs12116782 chr1:90032047 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.7 -0.38 1.48e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC trans rs7120489 0.643 rs11022353 chr11:12446727 G/C cg08537300 chr5:179058959 NA 0.57 6.18 0.32 1.84e-9 Mortality in heart failure; LIHC cis rs644799 0.763 rs2950521 chr11:95536870 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1865721 0.682 rs3745081 chr18:73142923 A/G cg26385618 chr18:73139727 C18orf62 -0.28 -7.69 -0.38 1.5700000000000001e-13 Intelligence; LIHC cis rs763121 0.853 rs2267393 chr22:39101619 G/C cg14440974 chr22:39074834 NA -0.37 -6.25 -0.32 1.21e-9 Menopause (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07549551 chr6:158487608 SYNJ2 0.42 6.11 0.31 2.74e-9 Longevity; LIHC trans rs4906332 1.000 rs17617832 chr14:103943140 T/C cg17675199 chr6:35436792 RPL10A 0.35 6.86 0.35 3.26e-11 Coronary artery disease; LIHC cis rs921968 0.541 rs667251 chr2:219384384 C/G cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs74181299 0.684 rs11126029 chr2:65338264 C/T cg05010058 chr2:65284262 CEP68 -0.41 -6.82 -0.35 4.07e-11 Pulse pressure; LIHC cis rs10883723 0.810 rs7912901 chr10:104277440 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs295140 0.605 rs34693942 chr2:201184348 T/C cg23649088 chr2:200775458 C2orf69 -0.45 -6.16 -0.32 2.01e-9 QT interval; LIHC cis rs6963495 0.818 rs117887993 chr7:105193837 T/G cg19920283 chr7:105172520 RINT1 0.66 5.96 0.31 6.23e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6076065 0.722 rs6048760 chr20:23345844 G/T cg11657817 chr20:23433608 CST11 -0.3 -6.27 -0.32 1.08e-9 Facial morphology (factor 15, philtrum width); LIHC cis rs9549367 0.789 rs71446682 chr13:113894908 A/G cg00898013 chr13:113819073 PROZ -0.42 -7.35 -0.37 1.46e-12 Platelet distribution width; LIHC cis rs2576037 0.526 rs2571027 chr18:44561516 C/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 0.47 6.76 0.34 5.88e-11 Personality dimensions; LIHC cis rs9309473 1.000 rs2056486 chr2:73717567 G/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.84 -0.35 3.68e-11 Metabolite levels; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg02290350 chr8:58132656 NA 0.5 10.94 0.51 4.54e-24 Developmental language disorder (linguistic errors); LIHC cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg12386194 chr3:101231763 SENP7 0.5 7.09 0.36 7.78e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs2071426 0.959 rs11188144 chr10:96789707 C/G cg09036531 chr10:96991505 NA -0.5 -5.91 -0.3 8.38e-9 Blood metabolite levels; LIHC cis rs1348850 0.526 rs2141157 chr2:178374112 C/T cg27490568 chr2:178487706 NA 1.0 11.25 0.52 3.51e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6831352 0.703 rs4235435 chr4:100039578 C/T cg12011299 chr4:100065546 ADH4 0.56 9.84 0.47 2.69e-20 Alcohol dependence; LIHC cis rs8177253 0.930 rs12595 chr3:133496553 T/C cg12373951 chr3:133503437 NA 0.69 12.49 0.56 9.55e-30 Iron status biomarkers; LIHC cis rs12893668 0.514 rs3212090 chr14:104168863 C/T cg24130564 chr14:104152367 KLC1 -0.54 -9.19 -0.45 3.77e-18 Reticulocyte count; LIHC cis rs1018836 0.786 rs7016220 chr8:91606848 A/G cg16814680 chr8:91681699 NA -0.56 -8.93 -0.43 2.62e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2594714 0.538 rs895819 chr19:13947292 A/G cg17299615 chr19:13944571 NA 0.55 7.95 0.4 2.68e-14 Breast cancer; LIHC cis rs3749237 0.615 rs55957735 chr3:49438158 G/A cg03060546 chr3:49711283 APEH 0.58 9.54 0.46 2.7e-19 Resting heart rate; LIHC cis rs9467711 0.517 rs16901784 chr6:26555433 C/A cg12826209 chr6:26865740 GUSBL1 0.6 5.91 0.3 8.39e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs7149337 0.837 rs4296182 chr14:51662167 A/C cg23942311 chr14:51606299 NA 0.35 6.95 0.35 1.84e-11 Cancer; LIHC cis rs7208859 0.573 rs73267829 chr17:29003939 G/A cg14067834 chr17:29058358 SUZ12P 0.6 5.88 0.3 9.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4820539 0.966 rs5759594 chr22:23470660 G/A cg21100191 chr22:23484243 RTDR1 0.93 17.1 0.68 8.16e-48 Bone mineral density; LIHC cis rs921968 0.541 rs2241527 chr2:219537224 A/G cg02176678 chr2:219576539 TTLL4 0.52 6.92 0.35 2.18e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs904251 0.797 rs1776460 chr6:37485484 A/G cg08126542 chr6:37504118 NA -0.41 -6.52 -0.33 2.47e-10 Cognitive performance; LIHC cis rs6840360 1.000 rs4696283 chr4:152580516 A/G cg22705602 chr4:152727874 NA -0.31 -6.46 -0.33 3.7e-10 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs7739232 0.920 rs77374381 chr6:53530662 A/G cg19801120 chr6:53530570 KLHL31 -0.86 -5.84 -0.3 1.21e-8 Hip circumference adjusted for BMI; LIHC cis rs4819052 0.819 rs13046807 chr21:46672286 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.76 0.39 9.62e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7551222 0.752 rs4252685 chr1:204496856 C/A cg20240347 chr1:204465584 NA -0.36 -7.5 -0.38 5.47e-13 Schizophrenia; LIHC cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg24209194 chr3:40518798 ZNF619 0.55 7.92 0.39 3.4e-14 Renal cell carcinoma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05977900 chr3:182512126 ATP11B 0.46 7.17 0.36 4.78e-12 Cognitive function; LIHC cis rs35883536 1.000 rs11583008 chr1:101085094 A/G cg14515779 chr1:101123966 NA -0.66 -12.4 -0.56 2.04e-29 Monocyte count; LIHC cis rs6466055 0.777 rs41562 chr7:104845094 C/T cg04380332 chr7:105027541 SRPK2 0.35 6.59 0.34 1.7e-10 Schizophrenia; LIHC cis rs919433 1.000 rs2195510 chr2:198161195 A/G cg10820045 chr2:198174542 NA -0.6 -10.3 -0.49 7.69e-22 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9457247 0.730 rs9459841 chr6:167431949 G/A cg12798992 chr6:167411361 FGFR1OP 0.5 7.68 0.38 1.7e-13 Crohn's disease; LIHC cis rs9341808 0.529 rs4706840 chr6:81057769 T/A cg08355045 chr6:80787529 NA 0.35 6.95 0.35 1.89e-11 Sitting height ratio; LIHC cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.71 0.8 4.72e-78 Prudent dietary pattern; LIHC cis rs7523273 0.606 rs2488253 chr1:207938709 C/A cg22525895 chr1:207977042 MIR29B2 0.63 10.2 0.48 1.65e-21 Schizophrenia; LIHC cis rs5770917 1.000 rs3213446 chr22:51015674 C/T cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.42 -5.91 -0.3 8.19e-9 Narcolepsy; LIHC cis rs288342 0.832 rs288308 chr2:183651818 T/G cg02625481 chr2:183667124 NA -0.29 -5.97 -0.31 5.87e-9 Recurrent major depressive disorder; LIHC cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs526821 0.595 rs565859 chr11:55297367 T/C cg04317927 chr11:55418816 OR4S2 0.47 9.04 0.44 1.21e-17 Pediatric bone mineral density (spine); LIHC cis rs9916302 0.707 rs11078903 chr17:37631924 G/A cg00129232 chr17:37814104 STARD3 -0.44 -6.96 -0.35 1.79e-11 Glomerular filtration rate (creatinine); LIHC cis rs1461503 0.966 rs10892938 chr11:122841921 A/C cg14473756 chr11:122847823 NA -0.37 -6.74 -0.34 6.82e-11 Menarche (age at onset); LIHC trans rs944289 0.746 rs7145211 chr14:36558266 A/T cg15660807 chr2:220381734 ACCN4 -0.26 -6.35 -0.32 6.83e-10 Thyroid cancer; LIHC cis rs35306767 0.715 rs17221463 chr10:1038040 T/C cg20503657 chr10:835505 NA 0.83 7.8 0.39 7.53e-14 Eosinophil percentage of granulocytes; LIHC cis rs4474465 0.850 rs7938257 chr11:78224908 A/G cg27205649 chr11:78285834 NARS2 0.42 6.21 0.32 1.53e-9 Alzheimer's disease (survival time); LIHC cis rs743757 1.000 rs2236954 chr3:50425177 C/A cg12708802 chr3:50388878 TUSC4;CYB561D2 0.52 8.1 0.4 9.68e-15 Diastolic blood pressure; LIHC cis rs2257205 0.667 rs9889494 chr17:56629764 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC trans rs4596713 0.508 rs4745650 chr9:71777892 G/A cg16512924 chr15:28394682 HERC2 0.39 6.25 0.32 1.21e-9 Headache; LIHC cis rs3770081 1.000 rs75713195 chr2:86290659 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -8.49 -0.42 6.21e-16 Facial emotion recognition (sad faces); LIHC cis rs8062405 0.723 rs12445744 chr16:28588395 A/C cg16576597 chr16:28551801 NUPR1 0.49 7.54 0.38 4.29e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs3741151 1.000 rs75912489 chr11:73073846 G/A cg17517138 chr11:73019481 ARHGEF17 0.9 6.51 0.33 2.74e-10 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs265548 0.538 rs36688 chr19:17911212 A/C cg16744531 chr19:17905626 B3GNT3 0.59 8.91 0.43 3e-17 Tumor biomarkers; LIHC cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg21724239 chr8:58056113 NA 0.61 7.69 0.38 1.63e-13 Developmental language disorder (linguistic errors); LIHC cis rs74233809 1.000 rs12220375 chr10:104901491 T/C cg03493300 chr10:104813866 CNNM2 0.47 6.05 0.31 3.83e-9 Birth weight; LIHC cis rs6952809 0.532 rs10227362 chr7:2456799 A/G cg23289794 chr7:2394357 EIF3B -0.64 -6.46 -0.33 3.64e-10 Multiple sclerosis; LIHC cis rs4970988 0.787 rs1532770 chr1:150725335 G/T cg17724175 chr1:150552817 MCL1 0.47 9.27 0.45 2.13e-18 Urate levels; LIHC cis rs4332037 0.539 rs11764780 chr7:2020904 G/C cg23422044 chr7:1970798 MAD1L1 -0.61 -6.88 -0.35 2.86e-11 Bipolar disorder; LIHC cis rs7577696 0.525 rs11124272 chr2:32142520 A/C cg02381751 chr2:32503542 YIPF4 0.43 6.0 0.31 5.1e-9 Inflammatory biomarkers; LIHC cis rs875971 1.000 rs778706 chr7:65860424 A/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs67460515 0.892 rs1382429 chr3:161015153 T/C cg17135325 chr3:160939158 NMD3 0.54 7.62 0.38 2.59e-13 Parkinson's disease; LIHC cis rs2991971 0.903 rs2991973 chr1:46020632 G/A cg03146154 chr1:46216737 IPP -0.38 -5.88 -0.3 9.8e-9 High light scatter reticulocyte count; LIHC cis rs2952156 0.920 rs732083 chr17:37834367 G/A cg00129232 chr17:37814104 STARD3 -0.54 -10.39 -0.49 3.59e-22 Asthma; LIHC cis rs644799 0.965 rs10831426 chr11:95505888 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.41 5.73 0.3 2.25e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs12310956 0.532 rs7306007 chr12:33975209 C/G cg26384229 chr12:38710491 ALG10B 0.49 6.71 0.34 8.25e-11 Morning vs. evening chronotype; LIHC cis rs9318086 0.901 rs7336730 chr13:24452104 T/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.53 -10.64 -0.5 5.08e-23 Myopia (pathological); LIHC cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg10295955 chr4:187884368 NA -0.96 -22.55 -0.77 1.2e-69 Lobe attachment (rater-scored or self-reported); LIHC cis rs2279817 0.818 rs867984 chr1:17982559 G/A cg21791023 chr1:18019539 ARHGEF10L -0.52 -6.27 -0.32 1.06e-9 Neuroticism; LIHC cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg01788221 chr16:89496183 ANKRD11 -0.37 -5.79 -0.3 1.56e-8 Multiple myeloma (IgH translocation); LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.86e-9 Total body bone mineral density; LIHC cis rs35110281 0.807 rs6518301 chr21:45016818 T/C cg21573476 chr21:45109991 RRP1B -0.52 -9.8 -0.47 3.7799999999999997e-20 Mean corpuscular volume; LIHC cis rs11792861 0.781 rs72607158 chr9:111763010 T/C cg13535736 chr9:111863775 C9orf5 -0.41 -6.11 -0.31 2.68e-9 Menarche (age at onset); LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.72 10.73 0.5 2.5e-23 Lymphocyte counts; LIHC cis rs7715806 0.509 rs34349 chr5:74944868 A/G cg06933384 chr5:74808293 COL4A3BP;POLK -0.43 -6.06 -0.31 3.66e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9595066 0.715 rs9567366 chr13:44682973 A/C cg04068111 chr13:44716778 NA 0.36 6.63 0.34 1.3e-10 Schizophrenia; LIHC cis rs12497850 0.931 rs9755490 chr3:48871664 A/C cg07636037 chr3:49044803 WDR6 0.93 16.69 0.67 3.76e-46 Parkinson's disease; LIHC cis rs9378688 0.654 rs13196306 chr6:2252322 A/G cg12303981 chr6:2244766 GMDS -0.45 -6.02 -0.31 4.57e-9 Caudate nucleus volume; LIHC cis rs4699052 0.507 rs7662107 chr4:104258396 C/T cg16532752 chr4:104119610 CENPE -0.49 -6.67 -0.34 1e-10 Testicular germ cell tumor; LIHC cis rs6570726 0.764 rs9403726 chr6:145901686 G/T cg13319975 chr6:146136371 FBXO30 -0.36 -5.73 -0.3 2.21e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18093693 chr15:72668265 HEXA;C15orf34 0.47 7.08 0.36 8.21e-12 Pancreatic cancer; LIHC cis rs6728642 0.572 rs13403225 chr2:97600827 A/G cg26665480 chr2:98280029 ACTR1B -0.51 -6.45 -0.33 3.73e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs2980439 0.525 rs2980508 chr8:8171732 C/T cg06636001 chr8:8085503 FLJ10661 0.56 8.99 0.44 1.78e-17 Neuroticism; LIHC cis rs6570726 0.905 rs406799 chr6:145821837 G/C cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs4820539 1.000 rs4822360 chr22:23482460 A/G cg14186256 chr22:23484241 RTDR1 0.9 18.19 0.7 3.33e-52 Bone mineral density; LIHC cis rs9914988 0.887 rs4795464 chr17:27146497 G/C cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs12477438 0.520 rs11890338 chr2:99767868 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.82 0.65 1.12e-42 Chronic sinus infection; LIHC cis rs6061231 0.624 rs8668 chr20:60964064 C/T cg24112000 chr20:60950667 NA 0.58 8.64 0.42 2.18e-16 Colorectal cancer; LIHC cis rs6120849 0.754 rs3746436 chr20:33586193 C/T cg06115741 chr20:33292138 TP53INP2 0.5 5.74 0.3 2.14e-8 Protein C levels; LIHC cis rs1046896 1.000 rs1046896 chr17:80685533 A/G cg02711726 chr17:80685570 FN3KRP 0.59 11.87 0.54 1.93e-27 Glycated hemoglobin levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg06567722 chr13:113834331 PCID2 0.37 6.44 0.33 3.99e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs11023332 0.832 rs10832289 chr11:14669496 A/T cg00085434 chr11:14927489 NA -0.4 -5.75 -0.3 1.94e-8 Adiponectin levels;Vitamin D levels; LIHC cis rs600806 0.850 rs3768494 chr1:109935427 A/G cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.17 -0.36 4.54e-12 Intelligence (multi-trait analysis); LIHC cis rs4742903 0.967 rs2417485 chr9:106867106 A/C cg14250997 chr9:106856677 SMC2 0.43 7.48 0.37 6.3e-13 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12785082 chr7:101662332 CUX1 0.42 6.26 0.32 1.14e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs13126513 0.708 rs7665289 chr4:100448167 G/T cg05468953 chr4:100565104 NA 0.33 6.5 0.33 2.82e-10 Metabolite levels (MHPG); LIHC cis rs7903847 0.596 rs10786340 chr10:99156563 G/C cg06359132 chr10:99160096 RRP12 -0.42 -6.47 -0.33 3.42e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs7618501 1.000 rs57648519 chr3:49813169 C/A cg21659725 chr3:3221576 CRBN 0.99 19.66 0.73 4.28e-58 Intelligence (multi-trait analysis); LIHC cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg06453172 chr10:134556979 INPP5A -0.63 -8.41 -0.41 1.11e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9733 0.596 rs72702504 chr1:150635374 G/C cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs10752881 1.000 rs12035773 chr1:182985716 A/G ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs858239 0.600 rs10235786 chr7:23139940 T/C cg18081818 chr7:23246105 NA -0.38 -5.76 -0.3 1.91e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs6456156 0.586 rs7762156 chr6:167485831 A/T cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.07e-9 Primary biliary cholangitis; LIHC trans rs6912958 0.684 rs4707382 chr6:88320641 T/C cg23605328 chr1:201951606 RNPEP 0.4 6.37 0.33 6.26e-10 Monocyte percentage of white cells; LIHC cis rs919433 0.713 rs10172961 chr2:198446859 T/C cg10820045 chr2:198174542 NA 0.49 7.73 0.39 1.24e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg27432699 chr2:27873401 GPN1 -0.54 -7.83 -0.39 6.28e-14 Total body bone mineral density; LIHC cis rs910316 0.737 rs175424 chr14:75626257 T/C cg08847533 chr14:75593920 NEK9 -0.86 -17.12 -0.68 6.61e-48 Height; LIHC cis rs72780191 0.574 rs55836224 chr2:23895597 T/C cg08917208 chr2:24149416 ATAD2B 0.66 6.21 0.32 1.55e-9 White blood cell count; LIHC cis rs7927592 0.913 rs3758643 chr11:68367193 C/T cg16797656 chr11:68205561 LRP5 0.49 7.67 0.38 1.83e-13 Total body bone mineral density; LIHC trans rs877282 0.853 rs7079299 chr10:756455 A/G cg22713356 chr15:30763199 NA 1.33 11.69 0.53 8.42e-27 Uric acid levels; LIHC cis rs1003719 0.715 rs58008706 chr21:38540506 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.64 -0.5 5.15e-23 Eye color traits; LIHC trans rs875971 0.508 rs10258739 chr7:66062935 A/T cg26939375 chr7:64535504 NA -0.42 -7.21 -0.36 3.69e-12 Aortic root size; LIHC cis rs875971 0.862 rs778684 chr7:65836403 A/T cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs10876993 0.928 rs1689587 chr12:58075398 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.25 -0.32 1.23e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs10845606 1.000 rs10845610 chr12:12839107 G/A cg09462578 chr12:12878428 APOLD1 -0.75 -9.91 -0.47 1.57e-20 Systemic lupus erythematosus; LIHC cis rs7829975 0.902 rs777707 chr8:8584344 A/G cg15556689 chr8:8085844 FLJ10661 0.36 5.76 0.3 1.91e-8 Mood instability; LIHC cis rs6500602 0.893 rs4785962 chr16:4484328 A/G cg08645402 chr16:4508243 NA 0.39 7.21 0.36 3.59e-12 Schizophrenia; LIHC cis rs6951245 0.580 rs78894484 chr7:1138721 T/G cg22907277 chr7:1156413 C7orf50 0.86 8.15 0.4 6.97e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2816062 0.747 rs2816049 chr1:18893768 A/G cg18795169 chr1:18902165 NA -0.8 -17.92 -0.7 4.12e-51 Urate levels in lean individuals; LIHC cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg03806693 chr22:41940476 POLR3H -1.08 -12.14 -0.55 1.9e-28 Vitiligo; LIHC cis rs963731 0.649 rs2123879 chr2:39292598 A/G cg04010122 chr2:39346883 SOS1 -0.75 -6.25 -0.32 1.2e-9 Corticobasal degeneration; LIHC cis rs1707322 0.752 rs28568986 chr1:46207743 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11583043 1.000 rs11584222 chr1:101480110 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 8.64 0.42 2.21e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg23425280 chr12:56401806 NA -0.49 -6.12 -0.31 2.58e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs769267 0.930 rs2099334 chr19:19578450 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.16e-9 Tonsillectomy; LIHC cis rs3820068 0.581 rs6429762 chr1:15945595 A/C cg17385448 chr1:15911702 AGMAT 0.35 6.22 0.32 1.49e-9 Systolic blood pressure; LIHC cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg27297192 chr10:134578999 INPP5A 0.53 7.81 0.39 6.89e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg08499158 chr17:42289980 UBTF -0.52 -8.52 -0.42 5.11e-16 Total body bone mineral density; LIHC cis rs2839186 0.656 rs8128380 chr21:47665693 C/T cg12379764 chr21:47803548 PCNT -0.55 -7.69 -0.38 1.6e-13 Testicular germ cell tumor; LIHC cis rs11098499 0.722 rs1814814 chr4:120258124 C/G cg09307838 chr4:120376055 NA 0.64 9.9 0.47 1.73e-20 Corneal astigmatism; LIHC cis rs244293 0.765 rs17817442 chr17:53099514 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.48 7.2 0.36 3.97e-12 Menarche (age at onset); LIHC cis rs1801251 1.000 rs4973055 chr2:233720283 G/T cg08000102 chr2:233561755 GIGYF2 -0.76 -11.44 -0.53 7.14e-26 Coronary artery disease; LIHC cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.06 -0.61 9.31e-36 Alzheimer's disease; LIHC cis rs6860806 0.507 rs273912 chr5:131661349 A/C cg24060327 chr5:131705240 SLC22A5 0.81 12.74 0.57 1.09e-30 Breast cancer; LIHC cis rs1878931 0.597 rs2680221 chr16:3462595 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.42 -0.41 1.04e-15 Body mass index (adult); LIHC cis rs2274273 0.837 rs10141552 chr14:55746091 C/T cg01864836 chr14:55583639 NA 0.38 6.81 0.35 4.4e-11 Protein biomarker; LIHC cis rs4722404 0.835 rs6965630 chr7:3138656 A/G cg19214707 chr7:3157722 NA -0.34 -6.35 -0.32 7.01e-10 Atopic dermatitis; LIHC cis rs12220238 0.908 rs10824086 chr10:75912668 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs11971779 0.680 rs7788777 chr7:139055193 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg04352962 chr1:209979756 IRF6 0.39 5.99 0.31 5.36e-9 Cleft lip with or without cleft palate; LIHC cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg25894440 chr7:65020034 NA -0.53 -6.23 -0.32 1.35e-9 Diabetic kidney disease; LIHC cis rs4975616 0.869 rs452384 chr5:1330840 T/C cg06550200 chr5:1325588 CLPTM1L -0.69 -11.0 -0.51 2.64e-24 Lung cancer; LIHC cis rs155076 0.938 rs536209 chr13:21847714 C/T cg14456004 chr13:21872349 NA -1.17 -12.67 -0.57 2.05e-30 White matter hyperintensity burden; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg18802567 chr5:171433913 FBXW11 0.44 6.16 0.32 2.06e-9 Migraine with aura; LIHC cis rs4727027 0.769 rs10952797 chr7:148816722 A/T cg23583168 chr7:148888333 NA -0.69 -9.85 -0.47 2.6e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6952808 0.862 rs4721135 chr7:1912222 A/G cg14004847 chr7:1930337 MAD1L1 -0.44 -6.33 -0.32 7.61e-10 Bipolar disorder and schizophrenia; LIHC cis rs2302190 0.882 rs11658998 chr17:56655786 T/G cg05425664 chr17:57184151 TRIM37 -0.47 -5.89 -0.3 9.43e-9 Vitamin D levels; LIHC cis rs9381040 0.610 rs717883 chr6:41045270 T/C cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.79 -0.3 1.58e-8 Alzheimer's disease (late onset); LIHC trans rs4927850 1.000 rs7627868 chr3:195753473 A/T cg21051086 chr3:73046214 PPP4R2 -0.38 -6.08 -0.31 3.19e-9 Pancreatic cancer; LIHC cis rs2576037 0.558 rs7244778 chr18:44541915 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 11.24 0.52 3.7e-25 Personality dimensions; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg22522985 chr1:52485971 TXNDC12 0.48 6.41 0.33 4.88e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg04013166 chr16:89971882 TCF25 0.55 7.23 0.36 3.16e-12 Skin colour saturation; LIHC cis rs2832191 0.791 rs2832197 chr21:30497790 T/C cg24692254 chr21:30365293 RNF160 -0.59 -10.28 -0.49 8.89e-22 Dental caries; LIHC cis rs7546668 1.000 rs10803389 chr1:15861287 C/T cg11706911 chr1:15910989 AGMAT 0.44 6.77 0.34 5.54e-11 Glomerular filtration rate (creatinine); LIHC trans rs2727020 0.554 rs2866490 chr11:49425463 A/G cg18944383 chr4:111397179 ENPEP 0.35 8.04 0.4 1.48e-14 Coronary artery disease; LIHC cis rs3008870 0.883 rs2755249 chr1:67493662 A/G cg02640540 chr1:67518911 SLC35D1 0.45 6.19 0.32 1.69e-9 Lymphocyte percentage of white cells; LIHC cis rs4919087 0.748 rs793516 chr10:98987985 G/T cg25902810 chr10:99078978 FRAT1 -0.55 -6.31 -0.32 8.61e-10 Monocyte count; LIHC cis rs992157 0.835 rs6707559 chr2:219142773 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.78 12.41 0.56 1.83e-29 Colorectal cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg10771851 chr11:68204486 LRP5 -0.41 -6.24 -0.32 1.32e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs929354 0.772 rs2301914 chr7:157000176 T/C cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.87e-9 Body mass index; LIHC cis rs208515 0.518 rs12209790 chr6:66662965 T/C cg07460842 chr6:66804631 NA 0.78 8.89 0.43 3.7e-17 Exhaled nitric oxide levels; LIHC cis rs2859741 0.967 rs494157 chr1:37512995 C/T cg09363841 chr1:37513479 NA 0.19 6.0 0.31 4.95e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs10426930 0.816 rs2620809 chr19:5062488 A/G cg18473234 chr19:5097819 KDM4B -0.54 -6.9 -0.35 2.57e-11 Monocyte percentage of white cells; LIHC cis rs16854884 0.586 rs4613453 chr3:143735600 C/G cg06585982 chr3:143692056 C3orf58 0.57 7.45 0.37 7.82e-13 Economic and political preferences (feminism/equality); LIHC cis rs3096299 0.838 rs3102384 chr16:89411661 T/G cg06640241 chr16:89574553 SPG7 0.53 8.08 0.4 1.1e-14 Multiple myeloma (IgH translocation); LIHC cis rs655641 1.000 rs585820 chr11:85696670 G/A cg09030501 chr11:85779252 PICALM -0.5 -6.03 -0.31 4.17e-9 Platelet count; LIHC cis rs600806 0.888 rs3853500 chr1:109864269 T/C cg16275483 chr1:110013120 SYPL2 -0.5 -6.22 -0.32 1.44e-9 Intelligence (multi-trait analysis); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06752365 chr13:33920491 NA 0.32 6.04 0.31 3.95e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3731827 0.511 rs2289976 chr2:85818797 G/A cg16865965 chr2:85811662 VAMP5 0.41 5.82 0.3 1.36e-8 Prostate cancer; LIHC cis rs1862618 0.671 rs72644088 chr5:56241019 G/A cg12311346 chr5:56204834 C5orf35 0.45 6.13 0.31 2.48e-9 Initial pursuit acceleration; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg22903471 chr2:27725779 GCKR -0.48 -8.26 -0.41 3.13e-15 Total body bone mineral density; LIHC cis rs12188164 0.543 rs2434695 chr5:464177 C/G cg26072250 chr5:443457 EXOC3;C5orf55 0.46 6.85 0.35 3.47e-11 Cystic fibrosis severity; LIHC cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg02475777 chr4:1388615 CRIPAK 0.54 8.0 0.4 2e-14 Longevity; LIHC cis rs7845219 0.544 rs7001535 chr8:95921090 C/G cg13393036 chr8:95962371 TP53INP1 -0.31 -5.84 -0.3 1.21e-8 Type 2 diabetes; LIHC cis rs6088580 0.634 rs6059867 chr20:33078103 C/T cg08999081 chr20:33150536 PIGU 0.67 13.23 0.58 1.52e-32 Glomerular filtration rate (creatinine); LIHC cis rs2073499 1.000 rs76846888 chr3:50406058 C/T cg08207895 chr3:50388901 TUSC4;CYB561D2 0.68 6.81 0.35 4.49e-11 Schizophrenia; LIHC cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg05025164 chr4:1340916 KIAA1530 0.63 9.72 0.47 6.85e-20 Longevity; LIHC cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg22800045 chr5:56110881 MAP3K1 0.67 8.63 0.42 2.32e-16 Initial pursuit acceleration; LIHC cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg20607798 chr8:58055168 NA 0.6 7.25 0.37 2.79e-12 Developmental language disorder (linguistic errors); LIHC cis rs7903847 0.642 rs1537645 chr10:99149914 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.55 -0.33 2.11e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg11644478 chr21:40555479 PSMG1 -0.38 -5.87 -0.3 1.06e-8 Cognitive function; LIHC cis rs7107174 1.000 rs10793297 chr11:78009660 T/C cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs6088580 0.524 rs1853056 chr20:33262058 C/T cg08999081 chr20:33150536 PIGU -0.43 -7.18 -0.36 4.44e-12 Glomerular filtration rate (creatinine); LIHC cis rs365132 0.934 rs251844 chr5:176476605 T/A cg16309518 chr5:176445507 NA -0.56 -10.83 -0.51 1.11e-23 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs6063312 0.518 rs6122718 chr20:47346225 A/G cg18078177 chr20:47281410 PREX1 -0.52 -8.11 -0.4 9.04e-15 Tonometry; LIHC cis rs3784262 0.512 rs4646571 chr15:58343137 T/C cg12031962 chr15:58353849 ALDH1A2 -0.31 -6.17 -0.32 1.97e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC trans rs13139451 1.000 rs6533922 chr4:116421669 A/G cg22998206 chr12:49239429 DDX23 0.38 6.2 0.32 1.63e-9 Serum uric acid levels in response to allopurinol in gout; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20382932 chr2:71357258 MCEE;MPHOSPH10 0.48 6.16 0.32 2.06e-9 Lung function (FEV1/FVC); LIHC cis rs796364 0.951 rs281793 chr2:200847990 G/A cg23649088 chr2:200775458 C2orf69 0.51 6.13 0.31 2.48e-9 Schizophrenia; LIHC cis rs6598955 0.666 rs12759434 chr1:26607123 C/T cg00852783 chr1:26633632 UBXN11 0.51 8.58 0.42 3.41e-16 Obesity-related traits; LIHC cis rs7264396 0.676 rs6060727 chr20:34556000 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.53 -0.49 1.16e-22 Total cholesterol levels; LIHC cis rs921968 0.608 rs658378 chr2:219483881 T/A cg02985541 chr2:219472218 PLCD4 0.44 8.16 0.4 6.27e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs10911232 0.507 rs12037585 chr1:183000041 G/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs1005277 0.541 rs2472177 chr10:38384015 T/G cg25427524 chr10:38739819 LOC399744 -0.68 -13.35 -0.59 5.14e-33 Extrinsic epigenetic age acceleration; LIHC cis rs9611565 0.559 rs7290991 chr22:41964361 C/G cg06634786 chr22:41940651 POLR3H -0.61 -6.53 -0.33 2.39e-10 Vitiligo; LIHC cis rs6933660 0.665 rs6921042 chr6:151732385 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.54 8.02 0.4 1.69e-14 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03270376 chr2:219536588 RNF25;STK36 0.5 7.69 0.38 1.58e-13 Pancreatic cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01045986 chr18:29671767 RNF138 0.46 6.49 0.33 3.03e-10 Lung function (FEV1/FVC); LIHC cis rs2425143 1.000 rs6060524 chr20:34221155 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.53 -5.77 -0.3 1.75e-8 Blood protein levels; LIHC cis rs2204008 0.715 rs11514282 chr12:38169056 G/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs17401966 0.800 rs12122029 chr1:10339822 G/A cg19773385 chr1:10388646 KIF1B -0.4 -7.22 -0.36 3.44e-12 Hepatocellular carcinoma; LIHC cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg04546413 chr19:29218101 NA 0.55 10.23 0.48 1.31e-21 Methadone dose in opioid dependence; LIHC cis rs6543140 0.964 rs62154972 chr2:103048738 G/A cg09003973 chr2:102972529 NA 0.52 5.87 0.3 1.03e-8 Blood protein levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25634484 chr8:8559074 CLDN23 0.5 6.44 0.33 4.12e-10 Lung function (FEV1/FVC); LIHC cis rs11628318 0.660 rs4906242 chr14:103085063 G/A cg23461800 chr14:103021989 NA -0.42 -5.87 -0.3 1.03e-8 Platelet count; LIHC cis rs7223966 1.000 rs8074771 chr17:61735865 C/T cg05941027 chr17:61774174 LIMD2 0.33 6.71 0.34 8.24e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs644799 0.965 rs602512 chr11:95561682 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10845606 1.000 rs10845605 chr12:12833468 T/C cg04607235 chr12:12878440 APOLD1 -0.72 -9.18 -0.44 4.11e-18 Systemic lupus erythematosus; LIHC cis rs7647973 1.000 rs9860055 chr3:49506900 C/T cg07636037 chr3:49044803 WDR6 -0.54 -6.66 -0.34 1.09e-10 Menarche (age at onset); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14283194 chr7:91763737 CYP51A1 -0.4 -6.11 -0.31 2.75e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg11301795 chr4:187892539 NA -0.29 -7.91 -0.39 3.51e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs1461503 0.868 rs11602682 chr11:122842315 A/T cg14473756 chr11:122847823 NA -0.36 -6.63 -0.34 1.29e-10 Menarche (age at onset); LIHC cis rs11955398 0.625 rs34395679 chr5:59954716 A/G cg02684056 chr5:59996105 DEPDC1B 0.43 6.08 0.31 3.16e-9 Intelligence (multi-trait analysis); LIHC cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg13944838 chr5:179740914 GFPT2 -0.49 -6.97 -0.35 1.64e-11 Height; LIHC cis rs7582180 0.629 rs10202326 chr2:100950237 A/G cg14675211 chr2:100938903 LONRF2 0.53 8.58 0.42 3.45e-16 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.791 rs1722023 chr11:49908136 G/C cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC cis rs4819052 0.851 rs4819049 chr21:46673086 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.73 0.54 6.22e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs6058796 1.000 rs34311932 chr20:31260997 T/C cg02600331 chr11:130417168 NA 0.36 7.78 0.39 8.61e-14 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs711245 0.748 rs2276671 chr2:36771701 C/A cg01206211 chr2:36825736 FEZ2 0.48 7.74 0.39 1.16e-13 Height; LIHC cis rs2576037 0.526 rs2051292 chr18:44484372 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.53 7.78 0.39 8.67e-14 Personality dimensions; LIHC cis rs67311347 1.000 rs4246666 chr3:40407670 C/T cg13409248 chr3:40428643 ENTPD3 0.4 6.64 0.34 1.2e-10 Renal cell carcinoma; LIHC cis rs11190604 0.767 rs11190520 chr10:102175309 T/C cg07080220 chr10:102295463 HIF1AN 0.44 6.02 0.31 4.49e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg13409248 chr3:40428643 ENTPD3 -0.45 -7.42 -0.37 9.23e-13 Renal cell carcinoma; LIHC cis rs7071206 0.947 rs10824560 chr10:79416901 C/T cg07817648 chr10:79422355 NA -0.35 -7.16 -0.36 4.9e-12 Bone mineral density; LIHC cis rs1862618 0.853 rs252910 chr5:56192983 G/A cg12311346 chr5:56204834 C5orf35 -0.63 -8.07 -0.4 1.23e-14 Initial pursuit acceleration; LIHC cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg20887711 chr4:1340912 KIAA1530 0.45 6.02 0.31 4.48e-9 Obesity-related traits; LIHC cis rs35306767 0.903 rs7074642 chr10:878359 A/G cg26597838 chr10:835615 NA 1.16 14.4 0.61 4.41e-37 Eosinophil percentage of granulocytes; LIHC cis rs2439831 1.000 rs2251538 chr15:43767209 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.83 0.43 5.6e-17 Lung cancer in ever smokers; LIHC cis rs2295359 0.824 rs4655679 chr1:67599657 A/G cg08029281 chr1:67600428 NA -0.35 -5.98 -0.31 5.75e-9 Psoriasis; LIHC cis rs6121246 0.567 rs6060247 chr20:30190720 C/G cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs4969178 0.965 rs4969179 chr17:76391454 A/C cg20026190 chr17:76395443 PGS1 0.44 7.1 0.36 7.28e-12 HDL cholesterol levels; LIHC cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg04317338 chr11:64019027 PLCB3 0.8 10.14 0.48 2.64e-21 Mean platelet volume; LIHC cis rs2455799 0.573 rs2455834 chr3:15753641 A/G cg12698662 chr3:15914712 MIR563 -0.4 -7.48 -0.38 6.13e-13 Mean platelet volume; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03383661 chr6:42714115 TBCC 0.44 6.24 0.32 1.33e-9 Pancreatic cancer; LIHC cis rs9640161 0.742 rs11983355 chr7:150016697 A/C cg12556325 chr7:150026731 C7orf29;LRRC61 -0.46 -8.16 -0.4 6.43e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs1023500 0.596 rs133369 chr22:42463814 C/T cg15557168 chr22:42548783 NA -0.42 -6.6 -0.34 1.61e-10 Schizophrenia; LIHC cis rs11758351 0.866 rs75091077 chr6:26207546 A/C cg23601095 chr6:26197514 HIST1H3D 0.54 5.79 0.3 1.58e-8 Gout;Renal underexcretion gout; LIHC cis rs10845606 0.581 rs11055015 chr12:12836679 T/G cg09462578 chr12:12878428 APOLD1 -0.52 -7.58 -0.38 3.17e-13 Systemic lupus erythematosus; LIHC cis rs4718428 0.705 rs4717331 chr7:66378886 C/T cg18252515 chr7:66147081 NA -0.68 -9.31 -0.45 1.65e-18 Corneal structure; LIHC cis rs4917300 0.657 rs6996685 chr8:143071894 C/A cg06573787 chr8:143070187 NA 0.27 5.74 0.3 2.07e-8 Amyotrophic lateral sclerosis; LIHC cis rs4819052 0.851 rs2236443 chr21:46678174 T/C cg22633049 chr21:46681294 NA -0.34 -6.11 -0.31 2.73e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs11640939 0.710 rs2972265 chr16:5041778 T/C cg26446499 chr5:77253555 NA 0.35 6.3 0.32 8.91e-10 Cancer; LIHC cis rs6120849 0.663 rs6119548 chr20:33552612 A/G cg24642439 chr20:33292090 TP53INP2 0.66 7.75 0.39 1.06e-13 Protein C levels; LIHC cis rs600806 0.778 rs2140923 chr1:110004990 C/T cg08911820 chr1:110026001 ATXN7L2 -0.65 -8.05 -0.4 1.36e-14 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg11890956 chr21:40555474 PSMG1 1.03 14.59 0.62 7.75e-38 Cognitive function; LIHC cis rs12478296 0.901 rs7603560 chr2:243043256 C/T cg18898632 chr2:242989856 NA -0.69 -8.67 -0.42 1.77e-16 Obesity-related traits; LIHC cis rs892961 0.806 rs312910 chr17:75413961 A/C cg01320579 chr17:75405842 SEPT9 0.51 8.83 0.43 5.64e-17 Airflow obstruction; LIHC cis rs748404 0.697 rs546170 chr15:43564849 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.42 6.42 0.33 4.43e-10 Lung cancer; LIHC cis rs875971 0.660 rs1860468 chr7:66107252 T/C cg18876405 chr7:65276391 NA -0.42 -7.27 -0.37 2.54e-12 Aortic root size; LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.72 -0.34 7.62e-11 Lymphocyte counts; LIHC cis rs16866061 1.000 rs11694987 chr2:225397409 C/G cg12698349 chr2:225449008 CUL3 0.75 12.81 0.57 5.73e-31 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09888721 chr21:40178652 ETS2 0.41 5.78 0.3 1.66e-8 Cognitive function; LIHC cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg10755058 chr3:40428713 ENTPD3 0.35 5.78 0.3 1.72e-8 Renal cell carcinoma; LIHC cis rs36051895 0.632 rs12344116 chr9:5142216 G/A cg02405213 chr9:5042618 JAK2 -0.67 -11.49 -0.53 4.75e-26 Pediatric autoimmune diseases; LIHC cis rs9328573 0.935 rs12719732 chr15:100508847 C/G cg09918751 chr15:100517450 ADAMTS17 -0.44 -6.51 -0.33 2.74e-10 Urate levels in lean individuals; LIHC cis rs4700695 0.719 rs27082 chr5:65436152 A/C cg21114390 chr5:65439923 SFRS12 -0.54 -7.77 -0.39 9.51e-14 Facial morphology (factor 19); LIHC trans rs7395662 0.525 rs1945189 chr11:48418889 A/G cg15704280 chr7:45808275 SEPT13 -0.43 -6.54 -0.33 2.28e-10 HDL cholesterol; LIHC trans rs12478296 1.000 rs66612947 chr2:243035962 A/T cg01596870 chr19:55963115 NA -0.62 -8.23 -0.41 4.08e-15 Obesity-related traits; LIHC cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg09417038 chr21:47716443 C21orf57 -0.52 -7.83 -0.39 6.22e-14 Testicular germ cell tumor; LIHC cis rs1008375 1.000 rs6818639 chr4:17633049 A/G cg02297831 chr4:17616191 MED28 0.5 7.9 0.39 3.86e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg21448741 chr8:58168803 NA 0.38 7.06 0.36 9.34e-12 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.554 rs58020561 chr3:10054682 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.62e-13 Alzheimer's disease; LIHC cis rs929354 0.772 rs6967764 chr7:156994964 C/T cg17757837 chr7:157058334 UBE3C 0.74 12.11 0.55 2.47e-28 Body mass index; LIHC cis rs2430386 1.000 rs2430386 chr2:63178111 C/T cg17519650 chr2:63277830 OTX1 0.58 9.62 0.46 1.54e-19 Prostate cancer; LIHC cis rs9399137 0.507 rs13196486 chr6:135283874 C/G cg24558204 chr6:135376177 HBS1L 0.6 10.23 0.48 1.34e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs9911578 0.813 rs8066773 chr17:56601552 A/G cg05425664 chr17:57184151 TRIM37 -0.51 -7.26 -0.37 2.66e-12 Intelligence (multi-trait analysis); LIHC cis rs936229 0.813 rs4886629 chr15:75072558 G/C cg14664628 chr15:75095509 CSK -1.0 -19.91 -0.73 4.16e-59 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs11822910 0.737 rs2584858 chr11:57207077 C/T cg00522883 chr11:57194120 SLC43A3 0.56 7.68 0.38 1.69e-13 Platelet distribution width; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26251429 chr2:28113398 BRE;RBKS;LOC100302650 0.41 6.33 0.32 7.69e-10 Lung function (FEV1/FVC); LIHC cis rs6486730 0.508 rs7133440 chr12:129269244 A/C cg09035930 chr12:129282057 SLC15A4 -0.37 -6.25 -0.32 1.23e-9 Systemic lupus erythematosus; LIHC cis rs11148252 0.624 rs6561682 chr13:53266297 A/G cg00495681 chr13:53174319 NA -0.36 -5.75 -0.3 1.98e-8 Lewy body disease; LIHC cis rs61041384 0.661 rs79033960 chr12:123680935 T/C cg00376283 chr12:123451042 ABCB9 -0.55 -6.14 -0.32 2.29e-9 Schizophrenia; LIHC trans rs1814175 0.781 rs2866734 chr11:49886338 A/G cg03929089 chr4:120376271 NA -0.89 -18.29 -0.7 1.34e-52 Height; LIHC cis rs6500602 0.653 rs3747579 chr16:4445327 A/G cg08645402 chr16:4508243 NA -0.37 -6.32 -0.32 8.29e-10 Schizophrenia; LIHC cis rs244293 0.965 rs244335 chr17:53201930 C/G cg19360675 chr17:53046073 COX11;STXBP4 0.48 7.26 0.37 2.69e-12 Menarche (age at onset); LIHC cis rs2404618 0.624 rs7012381 chr8:1475357 C/T cg13402656 chr8:1511478 DLGAP2 -0.39 -7.43 -0.37 8.94e-13 Lung cancer; LIHC cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.86 -11.84 -0.54 2.51e-27 Alzheimer's disease; LIHC cis rs7119038 0.818 rs2077579 chr11:118619047 T/G cg19308663 chr11:118741387 NA 0.44 5.92 0.3 7.81e-9 Sjögren's syndrome; LIHC cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg16049864 chr8:95962084 TP53INP1 -0.6 -11.49 -0.53 4.52e-26 Type 2 diabetes; LIHC cis rs3008870 0.755 rs1535365 chr1:67497613 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.66 11.12 0.52 9.84e-25 Lymphocyte percentage of white cells; LIHC cis rs6570726 1.000 rs405622 chr6:145871897 G/T cg23711669 chr6:146136114 FBXO30 0.54 9.27 0.45 2.14e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs8072100 0.811 rs1912483 chr17:45443494 A/G cg08085267 chr17:45401833 C17orf57 -0.58 -8.64 -0.42 2.22e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7537052 0.669 rs6686192 chr1:36642991 C/T cg24686825 chr1:36642396 MAP7D1 -0.46 -8.52 -0.42 5.01e-16 Schizophrenia; LIHC cis rs933688 1.000 rs6865495 chr5:90746424 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.92 17.78 0.69 1.45e-50 Smoking behavior; LIHC trans rs4718428 0.705 rs13227468 chr7:66433563 T/C cg10756647 chr7:56101905 PSPH 0.65 8.91 0.43 3.18e-17 Corneal structure; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00380172 chr6:148663585 SASH1 0.46 7.09 0.36 7.59e-12 Calcium levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06766273 chr11:62521983 ZBTB3 0.39 6.18 0.32 1.85e-9 Cognitive function; LIHC cis rs4908760 0.613 rs4908511 chr1:8812390 C/G cg20416874 chr1:8611966 RERE 0.56 10.52 0.49 1.33e-22 Vitiligo; LIHC trans rs61931739 0.500 rs28624237 chr12:34457171 G/T cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs15676 0.947 rs2293966 chr9:131591832 G/A cg13708974 chr9:131466143 PKN3 0.38 5.79 0.3 1.64e-8 Blood metabolite levels; LIHC cis rs2439831 0.867 rs28729853 chr15:43673680 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.76 11.13 0.52 9.12e-25 Lung cancer in ever smokers; LIHC cis rs2288073 0.965 rs72789923 chr2:24394504 A/C cg06627628 chr2:24431161 ITSN2 -0.56 -7.21 -0.36 3.61e-12 Venous thromboembolism (SNP x SNP interaction); LIHC trans rs2018683 0.621 rs10261556 chr7:28976636 G/T cg19402173 chr7:128379420 CALU -0.4 -6.37 -0.33 5.95e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs10504073 0.669 rs818560 chr8:50035417 C/T cg00325661 chr8:49890786 NA 0.32 7.26 0.37 2.64e-12 Blood metabolite ratios; LIHC cis rs2637266 0.967 rs4581393 chr10:78376123 A/C cg18941641 chr10:78392320 NA 0.29 6.36 0.32 6.66e-10 Pulmonary function; LIHC trans rs79976124 0.837 rs75346757 chr6:66648386 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.77 0.34 5.63e-11 Type 2 diabetes; LIHC cis rs11577318 0.853 rs4471263 chr1:26622700 C/T cg18121669 chr1:26560928 CCDC21 0.49 7.88 0.39 4.31e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs1577917 1.000 rs11758849 chr6:86708262 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.57 -0.46 2.31e-19 Response to antipsychotic treatment; LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.69 11.13 0.52 9.27e-25 Height; LIHC cis rs4727027 0.645 rs12704072 chr7:148904888 G/A cg23583168 chr7:148888333 NA -0.77 -11.85 -0.54 2.17e-27 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs72627509 0.857 rs55762216 chr4:57765731 G/C cg16868167 chr4:57843880 C4orf14;POLR2B -0.52 -7.3 -0.37 2.05e-12 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4474465 0.850 rs7938816 chr11:78266227 T/C cg02023728 chr11:77925099 USP35 -0.36 -6.24 -0.32 1.32e-9 Alzheimer's disease (survival time); LIHC cis rs11098499 0.954 rs3733523 chr4:120423719 C/T cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC cis rs918629 0.754 rs2112566 chr5:95288618 G/A cg10483112 chr5:95245456 ELL2 -0.37 -6.22 -0.32 1.42e-9 IgG glycosylation; LIHC cis rs757081 0.671 rs214091 chr11:17296463 A/C cg15432903 chr11:17409602 KCNJ11 -0.46 -5.99 -0.31 5.25e-9 Systolic blood pressure; LIHC cis rs12200782 0.932 rs12212145 chr6:26646418 T/A cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs7193541 0.826 rs56143602 chr16:74694692 T/C cg01733217 chr16:74700730 RFWD3 0.53 10.41 0.49 3.15e-22 Multiple myeloma; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg20630277 chr11:1968830 MRPL23 0.53 7.31 0.37 1.97e-12 Hepatitis; LIHC cis rs7903847 0.642 rs61863816 chr10:99128503 G/A cg06359132 chr10:99160096 RRP12 -0.4 -5.86 -0.3 1.09e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs9790314 0.875 rs459515 chr3:161092351 T/C cg03342759 chr3:160939853 NMD3 -0.67 -9.14 -0.44 5.61e-18 Morning vs. evening chronotype; LIHC cis rs796364 0.806 rs6743396 chr2:200860138 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.68 7.39 0.37 1.14e-12 Schizophrenia; LIHC cis rs514406 0.679 rs960570 chr1:53237763 A/G cg27535305 chr1:53392650 SCP2 0.32 6.31 0.32 8.74e-10 Monocyte count; LIHC cis rs11711311 1.000 rs62268168 chr3:113489447 A/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.23 0.45 2.97e-18 IgG glycosylation; LIHC cis rs909002 0.849 rs10914453 chr1:32075036 A/G cg13919466 chr1:32135498 COL16A1 -0.31 -6.21 -0.32 1.57e-9 Intelligence (multi-trait analysis); LIHC trans rs2073499 0.935 rs2526392 chr3:50191191 T/C cg21659725 chr3:3221576 CRBN -0.62 -6.57 -0.33 1.82e-10 Schizophrenia; LIHC cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg18225595 chr11:63971243 STIP1 0.65 8.17 0.4 5.95e-15 Mean platelet volume; LIHC cis rs6088813 1.000 rs6142374 chr20:33985568 C/T cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC cis rs250677 0.687 rs250671 chr5:148446523 T/C cg18129178 chr5:148520854 ABLIM3 -0.48 -7.44 -0.37 8.34e-13 Breast cancer; LIHC cis rs262150 0.579 rs4481540 chr7:158785846 A/G cg13444538 chr7:158905317 VIPR2 -0.31 -5.97 -0.31 6.02e-9 Facial morphology (factor 20); LIHC cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg02951883 chr7:2050386 MAD1L1 -0.62 -9.53 -0.46 2.97e-19 Bipolar disorder and schizophrenia; LIHC cis rs1843834 0.858 rs12105685 chr2:225513164 A/G cg22455342 chr2:225449267 CUL3 0.46 5.96 0.31 6.34e-9 IgE levels in asthmatics (D.p. specific); LIHC trans rs7246657 0.943 rs10422967 chr19:37850137 T/C cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs6570726 0.791 rs11155435 chr6:145938545 T/C cg13319975 chr6:146136371 FBXO30 -0.43 -6.74 -0.34 6.68e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg18306943 chr3:40428807 ENTPD3 0.42 7.44 0.37 8.23e-13 Renal cell carcinoma; LIHC cis rs9640161 0.711 rs55881542 chr7:150025734 G/A cg27494647 chr7:150038898 RARRES2 0.32 5.84 0.3 1.19e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs2637266 0.783 rs2395434 chr10:78476161 T/C cg18941641 chr10:78392320 NA 0.27 5.82 0.3 1.33e-8 Pulmonary function; LIHC cis rs34375054 0.573 rs12581367 chr12:125654641 T/C cg25124228 chr12:125621409 AACS -0.43 -6.73 -0.34 7.11e-11 Post bronchodilator FEV1/FVC ratio; LIHC cis rs17666538 0.535 rs1669658 chr8:607380 A/G cg07234876 chr8:600039 NA 0.99 7.74 0.39 1.14e-13 IgG glycosylation; LIHC cis rs1865760 0.516 rs10807007 chr6:26048931 A/C cg17691542 chr6:26056736 HIST1H1C 0.44 6.28 0.32 1.04e-9 Height; LIHC cis rs860295 0.812 rs6657670 chr1:155787867 C/T cg02153340 chr1:155202674 NA -0.34 -6.17 -0.32 1.9e-9 Body mass index; LIHC cis rs2842992 0.724 rs9365097 chr6:160211259 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.51 9.26 0.45 2.32e-18 Age-related macular degeneration (geographic atrophy); LIHC cis rs4243830 1.000 rs34757678 chr1:6583270 C/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.8 7.84 0.39 5.87e-14 Body mass index; LIHC cis rs6782228 0.527 rs6767383 chr3:128413587 C/A cg16766828 chr3:128327626 NA -0.38 -6.06 -0.31 3.66e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC trans rs17685 0.753 rs6465000 chr7:75787417 G/A cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2562456 0.876 rs62110202 chr19:21754601 C/T cg23367146 chr19:21773418 NA 0.4 6.3 0.32 9.19e-10 Pain; LIHC cis rs875971 0.545 rs35459055 chr7:65944386 G/A cg11764359 chr7:65958608 NA 0.58 8.22 0.41 4.2e-15 Aortic root size; LIHC cis rs7493 0.755 rs13228784 chr7:94960825 A/G cg19678392 chr7:94953810 PON1 -0.45 -5.89 -0.3 8.99e-9 Yu-Zhi constitution type in type 2 diabetes; LIHC cis rs7249142 0.561 rs4808185 chr19:19296217 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.44 -7.28 -0.37 2.37e-12 IgG glycosylation; LIHC cis rs600806 0.714 rs12137189 chr1:110013215 A/G cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.27 -0.32 1.11e-9 Intelligence (multi-trait analysis); LIHC cis rs78545713 0.649 rs11757549 chr6:26231608 G/A cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs9486715 0.867 rs1127175 chr6:96999725 C/T cg18709589 chr6:96969512 KIAA0776 -0.35 -6.06 -0.31 3.51e-9 Headache; LIHC cis rs1982963 0.627 rs17124901 chr14:52488009 C/T cg10843707 chr14:52510701 NID2 0.37 5.97 0.31 5.83e-9 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs2363709 1.000 rs4241438 chr3:67425727 A/G cg13681781 chr9:139102396 QSOX2 0.83 6.35 0.32 6.79e-10 IgE levels; LIHC cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg20607798 chr8:58055168 NA 0.66 8.16 0.4 6.42e-15 Developmental language disorder (linguistic errors); LIHC trans rs6058796 1.000 rs6087963 chr20:31249144 G/C cg02600331 chr11:130417168 NA 0.35 7.53 0.38 4.6e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC trans rs61931739 0.500 rs34287388 chr12:34444626 C/A cg26384229 chr12:38710491 ALG10B 0.77 9.6 0.46 1.75e-19 Morning vs. evening chronotype; LIHC cis rs6963495 0.818 rs73190151 chr7:105152887 C/T cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs2777491 0.957 rs6493002 chr15:41709195 C/G cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.26 -0.45 2.37e-18 Ulcerative colitis; LIHC cis rs3741404 0.868 rs595880 chr11:64006466 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.95 -15.37 -0.64 6.45e-41 Platelet count; LIHC cis rs311392 0.902 rs2666874 chr8:55091561 A/T cg20636351 chr8:55087400 NA 0.37 7.67 0.38 1.81e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.25 0.8 2.71e-76 Prudent dietary pattern; LIHC cis rs1707322 0.721 rs11211158 chr1:46132850 C/G cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 0.572 rs3894323 chr3:10168967 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC cis rs7927771 0.965 rs4752881 chr11:47898535 A/G cg20307385 chr11:47447363 PSMC3 -0.44 -5.8 -0.3 1.53e-8 Subjective well-being; LIHC cis rs2153535 0.580 rs4960421 chr6:8459292 C/T cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg12292205 chr6:26970375 C6orf41 0.34 5.78 0.3 1.71e-8 Intelligence (multi-trait analysis); LIHC cis rs11577318 0.853 rs4471263 chr1:26622700 C/T cg00852783 chr1:26633632 UBXN11 0.41 6.66 0.34 1.12e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11122272 0.705 rs2572260 chr1:231486189 T/C cg06096015 chr1:231504339 EGLN1 0.5 9.35 0.45 1.21e-18 Hemoglobin concentration; LIHC cis rs2276314 1.000 rs2298715 chr18:33552425 T/C cg05985134 chr18:33552581 C18orf21 0.5 5.92 0.3 7.8e-9 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg06634786 chr22:41940651 POLR3H -0.81 -8.84 -0.43 5.15e-17 Vitiligo; LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg11494091 chr17:61959527 GH2 0.44 8.12 0.4 8.34e-15 Prudent dietary pattern; LIHC cis rs7586673 0.893 rs889925 chr2:161971597 T/C cg22496339 chr2:162101262 NA 0.7 10.63 0.5 5.39e-23 Intelligence (multi-trait analysis); LIHC trans rs1814175 0.754 rs7103235 chr11:49699191 A/G cg15704280 chr7:45808275 SEPT13 -0.89 -14.95 -0.63 3.15e-39 Height; LIHC cis rs1816752 0.875 rs1050110 chr13:25009485 C/G cg02811702 chr13:24901961 NA 0.25 6.14 0.32 2.29e-9 Obesity-related traits; LIHC cis rs5770917 1.000 rs3213445 chr22:51015838 T/C cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.48 -5.91 -0.3 8.18e-9 Narcolepsy; LIHC cis rs611744 0.870 rs371878 chr8:109130620 T/G cg21045802 chr8:109455806 TTC35 0.5 8.48 0.42 6.86e-16 Dupuytren's disease; LIHC cis rs644799 0.862 rs1150361 chr11:95633805 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.88 15.36 0.64 7.59e-41 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9309473 0.898 rs10209517 chr2:73845392 C/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.75 -0.34 6.38e-11 Metabolite levels; LIHC cis rs2637266 0.745 rs2579732 chr10:78442778 T/C cg18941641 chr10:78392320 NA 0.26 5.73 0.3 2.23e-8 Pulmonary function; LIHC cis rs2204008 0.774 rs4534658 chr12:38246783 G/A cg26384229 chr12:38710491 ALG10B 0.82 10.22 0.48 1.43e-21 Bladder cancer; LIHC cis rs2303745 0.544 rs12710308 chr19:17395879 T/A cg10664184 chr19:17420304 DDA1 0.45 5.73 0.3 2.22e-8 Systemic lupus erythematosus; LIHC cis rs12479064 0.724 rs112900993 chr2:99948805 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -8.63 -0.42 2.37e-16 Chronic sinus infection; LIHC trans rs637571 0.522 rs12797319 chr11:65735672 G/A cg17712092 chr4:129076599 LARP1B 0.75 13.27 0.58 1.08e-32 Eosinophil percentage of white cells; LIHC cis rs35306767 0.714 rs67696450 chr10:1090684 C/T cg20503657 chr10:835505 NA 0.71 6.8 0.35 4.68e-11 Eosinophil percentage of granulocytes; LIHC cis rs9611565 0.568 rs5758441 chr22:42132888 C/A cg03806693 chr22:41940476 POLR3H 0.78 8.87 0.43 4.01e-17 Vitiligo; LIHC cis rs1712517 0.873 rs7913461 chr10:105001325 A/G cg05636881 chr10:105038444 INA 0.41 6.5 0.33 2.8e-10 Migraine; LIHC cis rs12477438 0.520 rs11890338 chr2:99767868 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.94 14.24 0.61 1.91e-36 Chronic sinus infection; LIHC cis rs801193 0.548 rs2659904 chr7:66178602 C/A cg18252515 chr7:66147081 NA -0.46 -6.64 -0.34 1.22e-10 Aortic root size; LIHC cis rs506338 0.517 rs1207179 chr11:64450795 C/T cg27209729 chr11:64428925 NRXN2 0.34 6.41 0.33 4.7e-10 Body mass index;Urate levels; LIHC cis rs16837677 0.826 rs76114442 chr1:156699977 G/A cg19377421 chr1:156697041 ISG20L2;C1orf66 0.68 7.69 0.38 1.58e-13 Sjögren's syndrome; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg25738037 chr1:168025549 DCAF6 0.4 6.49 0.33 3.1e-10 Bilirubin levels; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 23.97 0.79 3.39e-75 Prudent dietary pattern; LIHC cis rs7267979 0.565 rs6107059 chr20:25592431 C/A cg24626310 chr20:25276739 ABHD12;PYGB -0.42 -5.84 -0.3 1.22e-8 Liver enzyme levels (alkaline phosphatase); LIHC trans rs6600671 1.000 rs10903159 chr1:121181997 G/T cg09829573 chr1:144692074 NBPF9 -0.44 -8.07 -0.4 1.22e-14 Hip geometry; LIHC cis rs60012524 1 rs60012524 chr2:99559117 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -7.45 -0.37 7.58e-13 Chronic sinus infection; LIHC cis rs7572733 0.534 rs2574832 chr2:198704818 T/G cg00792783 chr2:198669748 PLCL1 0.47 6.91 0.35 2.38e-11 Dermatomyositis; LIHC cis rs611744 0.967 rs608115 chr8:109231948 T/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs8005677 1.000 rs8006396 chr14:23380850 A/G cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs1707322 0.650 rs4553239 chr1:46150486 C/A cg06784218 chr1:46089804 CCDC17 0.42 7.76 0.39 9.87e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs801193 0.935 rs2659899 chr7:66186721 A/G cg14393609 chr7:65229607 NA 0.36 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs10779751 0.960 rs11121712 chr1:11320329 G/C cg08854313 chr1:11322531 MTOR 0.87 15.77 0.65 1.66e-42 Body mass index; LIHC cis rs17685 0.753 rs11982200 chr7:75714883 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.25 -0.32 1.22e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9790314 0.586 rs1839491 chr3:161126429 C/A cg03342759 chr3:160939853 NMD3 -0.54 -8.53 -0.42 4.75e-16 Morning vs. evening chronotype; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg24179483 chr5:170814656 NPM1 -0.55 -6.39 -0.33 5.58e-10 Systolic blood pressure; LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg13409248 chr3:40428643 ENTPD3 0.41 6.77 0.34 5.65e-11 Renal cell carcinoma; LIHC cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg21724239 chr8:58056113 NA 0.47 6.17 0.32 1.96e-9 Developmental language disorder (linguistic errors); LIHC cis rs1023500 0.551 rs133379 chr22:42468535 A/G cg04733989 chr22:42467013 NAGA 0.66 9.34 0.45 1.23e-18 Schizophrenia; LIHC cis rs6088580 0.524 rs6088568 chr20:33265971 A/C cg07148914 chr20:33460835 GGT7 -0.51 -7.19 -0.36 4.11e-12 Glomerular filtration rate (creatinine); LIHC cis rs11764590 0.694 rs6972969 chr7:2099331 A/G cg23043544 chr7:2124092 MAD1L1 -0.41 -6.61 -0.34 1.49e-10 Neuroticism; LIHC cis rs11971779 0.680 rs7805767 chr7:139111415 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.29 0.49 8.39e-22 Diisocyanate-induced asthma; LIHC cis rs17401966 0.838 rs4475756 chr1:10387788 A/G cg15208524 chr1:10270712 KIF1B 0.41 6.27 0.32 1.11e-9 Hepatocellular carcinoma; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg06873352 chr17:61820015 STRADA 0.7 11.65 0.53 1.17e-26 Prudent dietary pattern; LIHC cis rs6547741 0.935 rs4666005 chr2:27855239 A/G cg27432699 chr2:27873401 GPN1 0.78 13.06 0.58 6.57e-32 Oral cavity cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18147735 chr4:39460314 LIAS;RPL9 0.49 6.33 0.32 7.6e-10 Lung function (FEV1/FVC); LIHC cis rs2274273 0.870 rs7160523 chr14:55594560 G/T cg04306507 chr14:55594613 LGALS3 0.35 6.82 0.35 4.04e-11 Protein biomarker; LIHC cis rs6570726 0.791 rs1935612 chr6:145906090 T/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.74 -0.3 2.13e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs1790761 0.692 rs674783 chr11:67339076 C/T cg01069141 chr11:67398826 TBX10;NUDT8 0.38 6.69 0.34 8.86e-11 Mean corpuscular volume; LIHC cis rs240764 0.746 rs240153 chr6:101067135 A/C cg09795085 chr6:101329169 ASCC3 0.5 7.05 0.36 1.02e-11 Neuroticism; LIHC cis rs10864907 0.614 rs12711745 chr2:113700355 T/C cg12858261 chr2:113808755 IL1F8 0.34 5.94 0.31 7.18e-9 Pulmonary function; LIHC cis rs2963155 0.518 rs9324918 chr5:142767160 T/C cg17617527 chr5:142782415 NR3C1 0.9 10.25 0.48 1.15e-21 Breast cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11747516 chr1:2518503 C1orf93 -0.46 -6.03 -0.31 4.17e-9 Systolic blood pressure; LIHC cis rs28595532 0.668 rs58467651 chr4:119349011 T/G cg21605333 chr4:119757512 SEC24D 1.02 8.39 0.41 1.33e-15 Cannabis dependence symptom count; LIHC cis rs11098499 0.863 rs11933966 chr4:120476715 G/A cg09307838 chr4:120376055 NA 0.75 11.44 0.53 6.88e-26 Corneal astigmatism; LIHC cis rs6570726 0.764 rs9403731 chr6:145907937 G/A cg23711669 chr6:146136114 FBXO30 0.63 10.52 0.49 1.27e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg06238570 chr21:40685208 BRWD1 0.61 7.28 0.37 2.36e-12 Cognitive function; LIHC cis rs4638749 0.677 rs7581595 chr2:108847885 A/G cg06795125 chr2:108905320 SULT1C2 -0.31 -6.31 -0.32 8.83e-10 Blood pressure; LIHC cis rs12477438 0.765 rs7571390 chr2:99626593 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.61 -0.38 2.62e-13 Chronic sinus infection; LIHC cis rs9616064 0.506 rs6008944 chr22:47060976 C/T cg05621596 chr22:47072043 GRAMD4 -0.59 -9.48 -0.46 4.54e-19 Urate levels in obese individuals; LIHC cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg07061783 chr6:25882402 NA -0.43 -6.03 -0.31 4.14e-9 Blood metabolite levels; LIHC trans rs7323507 0.636 rs2095531 chr13:110603337 A/G cg04135558 chr15:50979175 TRPM7 0.36 6.04 0.31 4.1e-9 Lung function (FVC); LIHC cis rs1552244 0.808 rs7615088 chr3:10035896 A/T cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs1580019 0.961 rs2392056 chr7:32498953 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.79 12.06 0.55 3.87e-28 Cognitive ability; LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.56 -7.98 -0.4 2.17e-14 Lymphocyte counts; LIHC cis rs4689592 0.622 rs2276968 chr4:7070118 T/G cg06697600 chr4:7070879 GRPEL1 -0.68 -10.86 -0.51 8.19e-24 Monocyte percentage of white cells; LIHC cis rs644799 0.525 rs3016206 chr11:95536724 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.24 0.58 1.34e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs10213084 1.000 rs28477577 chr4:147495971 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs6546550 0.901 rs11126251 chr2:70163434 A/C cg02498382 chr2:70120550 SNRNP27 -0.41 -6.92 -0.35 2.18e-11 Prevalent atrial fibrillation; LIHC cis rs9309711 0.698 rs9750503 chr2:3491772 A/G cg10845886 chr2:3471009 TTC15 0.62 11.29 0.52 2.48e-25 Neurofibrillary tangles; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.54 0.38 4.31e-13 Prudent dietary pattern; LIHC cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg21782813 chr7:2030301 MAD1L1 0.55 9.98 0.47 9.58e-21 Bipolar disorder and schizophrenia; LIHC trans rs1728785 1.000 rs11648314 chr16:68596775 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.72 0.34 7.8e-11 Ulcerative colitis; LIHC cis rs9549367 0.789 rs34448227 chr13:113884754 A/C cg18105134 chr13:113819100 PROZ -0.67 -11.64 -0.53 1.27e-26 Platelet distribution width; LIHC cis rs1448094 0.512 rs11117061 chr12:86250916 G/A cg02569458 chr12:86230093 RASSF9 0.49 6.51 0.33 2.67e-10 Major depressive disorder; LIHC trans rs1974653 0.781 rs175166 chr22:20116182 G/T cg20152630 chr19:46405944 MYPOP -0.48 -6.25 -0.32 1.19e-9 Schizophrenia; LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg11060661 chr22:24314208 DDT;DDTL 0.65 11.11 0.52 1.07e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.44 0.37 8.24e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs922107 0.846 rs9428043 chr1:90005132 T/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.51 -0.38 5.27e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs13191362 0.935 rs13212137 chr6:163010261 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7512552 0.809 rs828783 chr1:150376977 C/T cg15654264 chr1:150340011 RPRD2 0.7 11.39 0.52 1.08e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs8114671 0.562 rs2378294 chr20:33500378 G/A cg07148914 chr20:33460835 GGT7 0.64 9.79 0.47 4.11e-20 Height; LIHC cis rs9309711 0.666 rs6767 chr2:3483205 C/T cg10845886 chr2:3471009 TTC15 -0.44 -8.34 -0.41 1.87e-15 Neurofibrillary tangles; LIHC trans rs1814175 0.869 rs10769600 chr11:49681832 C/T cg03929089 chr4:120376271 NA -0.89 -17.59 -0.69 8.81e-50 Height; LIHC trans rs11098499 0.779 rs80242894 chr4:120375752 G/A cg25214090 chr10:38739885 LOC399744 0.61 9.85 0.47 2.53e-20 Corneal astigmatism; LIHC cis rs9814567 1.000 rs6804770 chr3:134230234 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.29 -0.55 5.27e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs77861329 1.000 rs6781635 chr3:52125343 A/G cg08692210 chr3:52188851 WDR51A 0.81 7.89 0.39 4.22e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs8072100 0.840 rs9900360 chr17:45491979 C/T cg25173405 chr17:45401733 C17orf57 -0.41 -5.72 -0.3 2.37e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.86 0.57 3.82e-31 Prudent dietary pattern; LIHC cis rs853679 0.550 rs1237875 chr6:28173010 A/G cg23485639 chr6:28045615 ZNF165 -0.44 -5.88 -0.3 9.84e-9 Depression; LIHC cis rs1799949 0.859 rs11657004 chr17:41442751 A/G cg05368731 chr17:41323189 NBR1 0.68 11.26 0.52 3.26e-25 Menopause (age at onset); LIHC cis rs9926296 0.618 rs8058179 chr16:89846987 C/T cg04287289 chr16:89883240 FANCA -0.37 -5.99 -0.31 5.26e-9 Vitiligo; LIHC cis rs7552404 0.691 rs1770890 chr1:76401117 A/G cg03433033 chr1:76189801 ACADM -0.56 -6.82 -0.35 4.26e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs644799 0.932 rs572015 chr11:95637416 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 15.72 0.65 2.8e-42 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg05484376 chr2:27715224 FNDC4 0.38 6.41 0.33 4.96e-10 Total body bone mineral density; LIHC cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg25072359 chr17:41440525 NA 0.38 6.18 0.32 1.82e-9 Menopause (age at onset); LIHC cis rs79057730 0.599 rs35928068 chr7:805363 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.8 9.17 0.44 4.54e-18 Initial pursuit acceleration; LIHC cis rs7208859 0.524 rs59923796 chr17:29064919 G/A cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4727027 0.631 rs62507511 chr7:148796080 C/A cg23583168 chr7:148888333 NA -0.68 -9.48 -0.46 4.57e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs240764 0.658 rs10457077 chr6:101196767 C/T cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.34e-9 Neuroticism; LIHC cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs11190604 0.767 rs7090150 chr10:102173446 G/T cg07080220 chr10:102295463 HIF1AN 0.45 6.13 0.31 2.39e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs546131 0.642 rs61881104 chr11:34838383 C/A cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.49 -0.33 3.05e-10 Lung disease severity in cystic fibrosis; LIHC cis rs12701220 0.817 rs1058727 chr7:1087095 A/G cg26769984 chr7:1090371 C7orf50 0.55 7.32 0.37 1.76e-12 Bronchopulmonary dysplasia; LIHC cis rs60871478 0.853 rs62432864 chr7:808405 T/G cg05535760 chr7:792225 HEATR2 0.81 11.26 0.52 3.03e-25 Cerebrospinal P-tau181p levels; LIHC cis rs600806 0.888 rs3853498 chr1:109860144 T/C cg23091122 chr1:110024289 SYPL2 -0.46 -6.06 -0.31 3.63e-9 Intelligence (multi-trait analysis); LIHC cis rs16866061 0.515 rs1027340 chr2:225370554 C/A cg22509189 chr2:225307070 NA -0.49 -7.28 -0.37 2.37e-12 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.18 -0.61 3.33e-36 Alzheimer's disease; LIHC cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.5 0.33 2.86e-10 Bipolar disorder; LIHC cis rs6754311 0.773 rs632632 chr2:136638216 A/G cg15123519 chr2:136567270 LCT -0.44 -9.07 -0.44 9.38e-18 Mosquito bite size; LIHC cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg22800045 chr5:56110881 MAP3K1 -0.57 -6.77 -0.34 5.63e-11 Initial pursuit acceleration; LIHC cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg12463550 chr7:65579703 CRCP 0.69 7.33 0.37 1.68e-12 Diabetic kidney disease; LIHC cis rs4141404 0.851 rs5997893 chr22:31556103 A/G cg13145458 chr22:31556086 RNF185 0.46 6.43 0.33 4.28e-10 Paclitaxel-induced neuropathy; LIHC trans rs7618501 1.000 rs3811696 chr3:49761605 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.68 -0.34 9.57e-11 Intelligence (multi-trait analysis); LIHC cis rs240764 0.697 rs239195 chr6:101132368 T/C cg09795085 chr6:101329169 ASCC3 0.45 6.08 0.31 3.18e-9 Neuroticism; LIHC cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg25894440 chr7:65020034 NA -0.52 -6.07 -0.31 3.44e-9 Diabetic kidney disease; LIHC cis rs4819052 0.851 rs8127834 chr21:46696109 G/A cg22633049 chr21:46681294 NA -0.37 -6.26 -0.32 1.12e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.44 0.56 1.41e-29 Prudent dietary pattern; LIHC cis rs9902453 0.791 rs3115090 chr17:28035014 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.78 0.6 1.17e-34 Coffee consumption (cups per day); LIHC trans rs2797160 0.547 rs1418645 chr6:125946476 T/A cg05039488 chr6:79577232 IRAK1BP1 -0.42 -6.18 -0.32 1.87e-9 Endometrial cancer; LIHC cis rs12079745 0.793 rs12074013 chr1:169133621 C/T cg09363564 chr1:169337483 NME7;BLZF1 -0.68 -6.43 -0.33 4.3e-10 QT interval; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg27130769 chr7:5417105 TNRC18 -0.41 -6.23 -0.32 1.35e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10751667 0.600 rs7395387 chr11:1008664 G/C cg06064525 chr11:970664 AP2A2 -0.45 -10.92 -0.51 5.28e-24 Alzheimer's disease (late onset); LIHC cis rs887797 0.557 rs8079198 chr17:64588496 T/C cg27019712 chr17:64599478 PRKCA -0.4 -6.85 -0.35 3.47e-11 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC trans rs17685 0.753 rs9691174 chr7:75790405 T/C cg19862616 chr7:65841803 NCRNA00174 0.94 19.29 0.72 1.3e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1005277 0.502 rs2800484 chr10:38542415 C/T cg25427524 chr10:38739819 LOC399744 -0.76 -15.25 -0.64 2.01e-40 Extrinsic epigenetic age acceleration; LIHC cis rs4555082 0.915 rs28594491 chr14:105758018 G/A cg10792982 chr14:105748885 BRF1 0.43 5.72 0.3 2.35e-8 Mean platelet volume;Platelet distribution width; LIHC cis rs9611519 0.780 rs1535048 chr22:41684093 C/T cg03806693 chr22:41940476 POLR3H -0.69 -8.27 -0.41 2.97e-15 Neuroticism; LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg22903471 chr2:27725779 GCKR -0.49 -8.49 -0.42 6.44e-16 Total body bone mineral density; LIHC cis rs11603020 0.950 rs78624400 chr11:57375463 G/C cg19752551 chr11:57585705 CTNND1 -0.47 -6.07 -0.31 3.4e-9 Blood protein levels; LIHC cis rs13118159 0.836 rs12647145 chr4:1338618 C/A cg16405210 chr4:1374714 KIAA1530 -0.54 -6.84 -0.35 3.56e-11 Longevity; LIHC cis rs67478160 0.643 rs11160762 chr14:104255083 A/G cg01849466 chr14:104193079 ZFYVE21 0.46 7.41 0.37 9.69e-13 Schizophrenia; LIHC cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.68 0.46 9.54e-20 Platelet count; LIHC cis rs6782228 0.606 rs2712417 chr3:128345179 A/G cg16766828 chr3:128327626 NA -0.41 -6.54 -0.33 2.25e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs67478160 0.643 rs6575997 chr14:104228546 C/T cg24130564 chr14:104152367 KLC1 0.37 6.22 0.32 1.47e-9 Schizophrenia; LIHC cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg06238570 chr21:40685208 BRWD1 0.59 7.07 0.36 8.98e-12 Cognitive function; LIHC cis rs12220238 0.915 rs11000988 chr10:76073723 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs965469 1.000 rs6037553 chr20:3313884 A/G cg25506879 chr20:3388711 C20orf194 -0.6 -6.88 -0.35 2.84e-11 IFN-related cytopenia; LIHC cis rs7618501 1.000 rs7648987 chr3:49868455 A/G cg24110177 chr3:50126178 RBM5 -0.46 -7.23 -0.36 3.19e-12 Intelligence (multi-trait analysis); LIHC cis rs9309473 1.000 rs6546836 chr2:73677833 A/G cg20560298 chr2:73613845 ALMS1 -0.52 -6.51 -0.33 2.65e-10 Metabolite levels; LIHC trans rs11098499 0.866 rs12513310 chr4:120288039 T/A cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs752092 1.000 rs752092 chr15:101781934 C/T cg25114630 chr15:101792522 CHSY1 -0.55 -6.89 -0.35 2.62e-11 Corneal structure; LIHC cis rs28374715 0.733 rs7167706 chr15:41569644 C/A cg18705301 chr15:41695430 NDUFAF1 -1.13 -14.05 -0.6 1.02e-35 Ulcerative colitis; LIHC cis rs3806843 0.966 rs10036519 chr5:140151701 C/T cg19875535 chr5:140030758 IK -0.36 -5.91 -0.3 8.4e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9457247 1.000 rs239935 chr6:167411788 G/A cg12798992 chr6:167411361 FGFR1OP 0.55 8.6 0.42 2.91e-16 Crohn's disease; LIHC cis rs9325144 0.555 rs7977200 chr12:38713745 C/T cg26384229 chr12:38710491 ALG10B 0.57 7.92 0.39 3.42e-14 Morning vs. evening chronotype; LIHC cis rs11924390 0.800 rs1648698 chr3:186449582 G/C cg12454167 chr3:186435060 KNG1 0.3 7.05 0.36 1.01e-11 Adiponectin levels; LIHC cis rs6066825 0.606 rs4810830 chr20:47219740 T/C cg18078177 chr20:47281410 PREX1 0.49 8.13 0.4 7.76e-15 Colorectal cancer; LIHC cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg27572855 chr1:25598939 RHD 0.42 9.06 0.44 1.05e-17 Erythrocyte sedimentation rate; LIHC cis rs17376456 1.000 rs12187701 chr5:93522290 A/G cg25358565 chr5:93447407 FAM172A 1.09 9.85 0.47 2.66e-20 Diabetic retinopathy; LIHC cis rs8062405 1.000 rs3888190 chr16:28889486 C/A cg07451762 chr16:28383216 NA 0.32 5.98 0.31 5.51e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs892961 0.899 rs7222532 chr17:75413302 G/C cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs7552404 0.727 rs12122939 chr1:76276353 T/C cg03433033 chr1:76189801 ACADM 0.58 7.29 0.37 2.14e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg04317338 chr11:64019027 PLCB3 0.87 10.96 0.51 3.84e-24 Mean platelet volume; LIHC cis rs801193 1.000 rs2707854 chr7:66212597 G/A cg11764359 chr7:65958608 NA 0.71 10.58 0.5 8.11e-23 Aortic root size; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg07677032 chr17:61819896 STRADA 0.44 6.5 0.33 2.88e-10 Prudent dietary pattern; LIHC cis rs7818688 0.697 rs17665737 chr8:95986306 A/G cg16049864 chr8:95962084 TP53INP1 0.6 6.35 0.32 6.81e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2404602 0.647 rs12440511 chr15:76993135 A/G cg03037974 chr15:76606532 NA -0.59 -9.9 -0.47 1.81e-20 Blood metabolite levels; LIHC cis rs1000083 0.605 rs1423499 chr5:96534195 A/G ch.5.96698337R chr5:96672581 NA 0.56 6.23 0.32 1.36e-9 Cisplatin-induced ototoxicity; LIHC cis rs4638749 0.677 rs7599646 chr2:108852343 C/T cg06795125 chr2:108905320 SULT1C2 0.31 6.13 0.31 2.4e-9 Blood pressure; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.65 9.43 0.45 6.24e-19 Lymphocyte counts; LIHC cis rs6840360 1.000 rs4696285 chr4:152605449 A/G cg22705602 chr4:152727874 NA -0.32 -6.81 -0.35 4.3e-11 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg24209194 chr3:40518798 ZNF619 0.52 7.73 0.39 1.17e-13 Renal cell carcinoma; LIHC cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg04267008 chr7:1944627 MAD1L1 -0.6 -9.21 -0.45 3.45e-18 Bipolar disorder and schizophrenia; LIHC cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg19774624 chr17:42201019 HDAC5 -0.81 -12.69 -0.57 1.65e-30 Total body bone mineral density; LIHC cis rs6952808 0.531 rs3800922 chr7:2184505 A/G cg04267008 chr7:1944627 MAD1L1 -0.51 -7.85 -0.39 5.42e-14 Bipolar disorder and schizophrenia; LIHC cis rs6088580 0.634 rs1890002 chr20:32919219 A/G cg08999081 chr20:33150536 PIGU -0.65 -12.63 -0.56 2.93e-30 Glomerular filtration rate (creatinine); LIHC cis rs858239 0.600 rs28483572 chr7:23131785 A/G cg23682824 chr7:23144976 KLHL7 0.42 6.29 0.32 9.59e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg08888203 chr3:10149979 C3orf24 0.56 6.39 0.33 5.32e-10 Alzheimer's disease; LIHC trans rs916888 0.773 rs199447 chr17:44812188 C/T cg26692224 chr17:62915920 LRRC37A3 -0.72 -6.84 -0.35 3.73e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg00798850 chr10:35625974 CCNY 0.55 6.85 0.35 3.38e-11 Hepatitis; LIHC cis rs10197940 0.789 rs2444256 chr2:152280365 C/T cg06191203 chr2:152266755 RIF1 -0.52 -9.41 -0.45 7.7e-19 Lung cancer; LIHC cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg03806693 chr22:41940476 POLR3H -1.08 -12.5 -0.56 8.97e-30 Vitiligo; LIHC cis rs763121 0.853 rs1013338 chr22:38974154 C/A cg06022373 chr22:39101656 GTPBP1 0.76 15.54 0.64 1.38e-41 Menopause (age at onset); LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg00656387 chr3:40428638 ENTPD3 -0.5 -8.53 -0.42 4.94e-16 Renal cell carcinoma; LIHC cis rs763121 0.853 rs5757253 chr22:39104320 C/T cg06022373 chr22:39101656 GTPBP1 0.74 14.82 0.63 9.64e-39 Menopause (age at onset); LIHC trans rs7246657 0.943 rs10404920 chr19:37881556 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs11758351 0.660 rs16891446 chr6:26226996 A/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs9300255 0.602 rs884548 chr12:123634122 A/G cg00376283 chr12:123451042 ABCB9 0.59 6.71 0.34 8.15e-11 Neutrophil percentage of white cells; LIHC cis rs2834256 0.847 rs3827181 chr21:35107734 C/T cg14850771 chr21:34775459 IFNGR2 0.4 6.04 0.31 4.1e-9 Red cell distribution width; LIHC cis rs17125944 0.615 rs7150808 chr14:53304871 C/T cg00686598 chr14:53173677 PSMC6 -0.85 -9.76 -0.47 5.14e-20 Alzheimer's disease (late onset); LIHC cis rs8180040 0.690 rs7640397 chr3:46989828 C/T cg16586182 chr3:47516702 SCAP -0.43 -7.62 -0.38 2.5e-13 Colorectal cancer; LIHC cis rs2637266 0.626 rs2583069 chr10:78546775 T/C cg18941641 chr10:78392320 NA 0.29 6.16 0.32 2.03e-9 Pulmonary function; LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg22903471 chr2:27725779 GCKR -0.52 -8.97 -0.44 2.02e-17 Menopause (age at onset); LIHC cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg08048268 chr3:133502702 NA 0.43 6.6 0.34 1.59e-10 Iron status biomarkers; LIHC cis rs752010 0.806 rs943375 chr1:42092152 A/G cg06885757 chr1:42089581 HIVEP3 0.28 5.77 0.3 1.81e-8 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs77633900 0.614 rs279997 chr15:76949262 T/C cg21673338 chr15:77095150 SCAPER -0.48 -7.33 -0.37 1.68e-12 Non-glioblastoma glioma;Glioma; LIHC trans rs11039798 0.614 rs8188910 chr11:48825740 C/T cg15704280 chr7:45808275 SEPT13 0.63 6.57 0.33 1.86e-10 Axial length; LIHC cis rs7208859 0.673 rs9912122 chr17:29140716 C/A cg14067834 chr17:29058358 SUZ12P 0.65 6.69 0.34 9.29e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs4650994 1.000 rs12138541 chr1:178518707 G/A cg05059571 chr16:84539110 KIAA1609 -0.39 -6.49 -0.33 2.94e-10 HDL cholesterol levels;HDL cholesterol; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17250947 chr3:42642016 NKTR 0.41 6.05 0.31 3.78e-9 Lung function (FEV1/FVC); LIHC cis rs2404618 0.593 rs7815979 chr8:1484887 A/G cg13402656 chr8:1511478 DLGAP2 -0.42 -8.07 -0.4 1.18e-14 Lung cancer; LIHC cis rs36051895 0.659 rs1575285 chr9:5267440 A/G cg02405213 chr9:5042618 JAK2 -0.57 -8.72 -0.43 1.24e-16 Pediatric autoimmune diseases; LIHC cis rs3015497 0.616 rs11157759 chr14:51087263 A/G cg09863266 chr14:51125203 SAV1 -0.38 -6.11 -0.31 2.73e-9 Mean platelet volume; LIHC cis rs3096299 0.503 rs9925045 chr16:89556476 T/C cg00750074 chr16:89608354 SPG7 -0.49 -7.96 -0.4 2.5e-14 Multiple myeloma (IgH translocation); LIHC cis rs67311347 0.577 rs2371129 chr3:40248393 C/T cg10755058 chr3:40428713 ENTPD3 -0.36 -5.82 -0.3 1.39e-8 Renal cell carcinoma; LIHC cis rs4853012 0.838 rs59570457 chr2:74344282 T/C cg01017244 chr2:74357527 NA 0.63 11.29 0.52 2.45e-25 Gestational age at birth (maternal effect); LIHC cis rs909341 0.909 rs914559 chr20:62369300 C/G cg03999872 chr20:62272968 STMN3 0.46 6.84 0.35 3.6e-11 Atopic dermatitis; LIHC cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg06466757 chr4:1255808 NA 0.34 5.73 0.3 2.25e-8 Obesity-related traits; LIHC cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg18713687 chr3:195489789 MUC4 0.65 9.67 0.46 1.06e-19 Lung disease severity in cystic fibrosis; LIHC cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg03034668 chr16:1723424 CRAMP1L -0.34 -5.82 -0.3 1.33e-8 Coronary artery disease; LIHC cis rs7833790 0.654 rs7835342 chr8:82698092 A/G cg17211192 chr8:82754475 SNX16 -0.53 -9.34 -0.45 1.27e-18 Diastolic blood pressure; LIHC cis rs17095355 1.000 rs12267714 chr10:111722052 C/T cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.83 -0.3 1.27e-8 Biliary atresia; LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg16405210 chr4:1374714 KIAA1530 -0.53 -7.95 -0.39 2.76e-14 Obesity-related traits; LIHC cis rs34172651 0.876 rs7186893 chr16:24806420 G/T cg04756594 chr16:24857601 SLC5A11 0.48 7.46 0.37 7.15e-13 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.846 rs6768818 chr3:160951648 A/G cg03342759 chr3:160939853 NMD3 -0.82 -13.51 -0.59 1.31e-33 Morning vs. evening chronotype; LIHC cis rs55702914 0.625 rs787989 chr2:198200123 G/A cg10820045 chr2:198174542 NA -0.4 -5.99 -0.31 5.39e-9 Major depression and alcohol dependence; LIHC cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs12220238 1.000 rs11000897 chr10:75911276 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.71 6.93 0.35 2.12e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs12464559 0.579 rs59444636 chr2:152526675 C/A cg01189475 chr2:152685088 ARL5A -0.69 -8.39 -0.41 1.32e-15 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs9394841 0.667 rs9394831 chr6:41753084 C/T cg17623882 chr6:41773611 USP49 -0.44 -5.85 -0.3 1.15e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs2439831 0.850 rs2277531 chr15:44069069 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.4 0.33 5.2e-10 Lung cancer in ever smokers; LIHC cis rs4474465 0.790 rs10899554 chr11:78265667 T/G cg27205649 chr11:78285834 NARS2 0.46 7.03 0.36 1.12e-11 Alzheimer's disease (survival time); LIHC trans rs3749237 1.000 rs11717256 chr3:49868520 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.63 9.65 0.46 1.24e-19 Resting heart rate; LIHC cis rs11792861 0.564 rs3816237 chr9:111718348 T/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.69 11.4 0.52 1.01e-25 Menarche (age at onset); LIHC cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.68 0.34 9.67e-11 Bipolar disorder; LIHC cis rs1395 0.710 rs11674947 chr2:27471996 A/G cg22903471 chr2:27725779 GCKR -0.4 -6.01 -0.31 4.75e-9 Blood metabolite levels; LIHC cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg09033563 chr22:24373618 LOC391322 0.52 6.75 0.34 6.38e-11 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs769267 0.930 rs10422819 chr19:19643028 C/A cg15052019 chr19:19431593 KIAA0892;SF4 0.46 6.26 0.32 1.17e-9 Tonsillectomy; LIHC cis rs870825 0.587 rs28454955 chr4:185632701 C/T cg04058563 chr4:185651563 MLF1IP 0.7 7.36 0.37 1.36e-12 Blood protein levels; LIHC cis rs2806561 1.000 rs1208932 chr1:23429122 T/G cg19743168 chr1:23544995 NA -0.39 -7.49 -0.38 5.79e-13 Height; LIHC cis rs10508774 1.000 rs11812263 chr10:32958312 A/G cg01819863 chr10:32635814 EPC1 0.64 5.86 0.3 1.11e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.26 0.45 2.24e-18 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10354764 chr16:3285464 ZNF200 0.44 6.62 0.34 1.38e-10 Pancreatic cancer; LIHC cis rs6674176 0.660 rs6680421 chr1:44408969 A/C cg12908607 chr1:44402522 ARTN 0.51 8.65 0.42 2.1e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs881375 0.867 rs6478487 chr9:123672777 C/T cg14580859 chr9:123691850 NA 0.38 6.63 0.34 1.3100000000000001e-10 Rheumatoid arthritis; LIHC trans rs875971 1.000 rs4718357 chr7:65960878 A/G cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.09e-10 Aortic root size; LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg06873352 chr17:61820015 STRADA 0.74 13.22 0.58 1.66e-32 Prudent dietary pattern; LIHC trans rs4356975 0.563 rs6600893 chr4:69978901 A/G cg18043070 chr17:72199725 RPL38 -0.39 -6.04 -0.31 4.12e-9 Obesity-related traits; LIHC cis rs2204008 0.692 rs11613378 chr12:38213138 T/A cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs970821 0.667 rs2385506 chr8:124744604 C/T cg00283535 chr8:124749564 ANXA13 0.42 7.7 0.38 1.46e-13 Breast cancer; LIHC cis rs11098699 0.821 rs7684799 chr4:124207659 C/T cg09941581 chr4:124220074 SPATA5 0.33 6.52 0.33 2.57e-10 Mosquito bite size; LIHC cis rs2576037 0.526 rs1789152 chr18:44433092 G/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.56 0.5 9.43e-23 Personality dimensions; LIHC cis rs9399137 0.507 rs35571217 chr6:135290355 T/C cg24558204 chr6:135376177 HBS1L 0.6 10.23 0.48 1.34e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs10504229 1.000 rs76270388 chr8:58195605 T/A cg20607798 chr8:58055168 NA 0.59 6.8 0.35 4.58e-11 Developmental language disorder (linguistic errors); LIHC trans rs9929218 0.551 rs3785133 chr16:68728611 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.89 20.09 0.74 8.03e-60 Colorectal cancer; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg17428694 chr1:163291564 NUF2 0.54 6.47 0.33 3.4e-10 Glycated hemoglobin levels; LIHC cis rs763121 0.925 rs4821815 chr22:39105707 G/A cg06022373 chr22:39101656 GTPBP1 0.69 13.52 0.59 1.14e-33 Menopause (age at onset); LIHC cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg05368731 chr17:41323189 NBR1 -0.72 -12.39 -0.56 2.31e-29 Menopause (age at onset); LIHC cis rs2386661 0.523 rs2386663 chr10:5652739 C/T cg17085576 chr10:5658249 NA -0.3 -5.85 -0.3 1.15e-8 Breast cancer; LIHC cis rs7312933 0.703 rs7957471 chr12:42545591 G/T cg17420585 chr12:42539391 GXYLT1 -0.37 -5.95 -0.31 6.69e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2242116 0.734 rs4683294 chr3:46979013 C/G cg02527881 chr3:46936655 PTH1R 0.3 5.79 0.3 1.64e-8 Birth weight; LIHC cis rs8062405 0.690 rs62034351 chr16:28565489 G/A cg00204512 chr16:28754710 NA 0.41 6.98 0.35 1.52e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2576037 0.526 rs642897 chr18:44396917 T/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.53e-12 Personality dimensions; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07763516 chr16:71496321 ZNF23 0.44 6.24 0.32 1.26e-9 Lung function (FEV1/FVC); LIHC cis rs10464366 0.517 rs13231075 chr7:39174806 G/T cg20302533 chr7:39170763 POU6F2 0.38 7.02 0.35 1.22e-11 IgG glycosylation; LIHC cis rs7772486 0.875 rs9399573 chr6:146403255 A/T cg13319975 chr6:146136371 FBXO30 -0.35 -5.88 -0.3 9.71e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.862 rs28470208 chr7:65584700 A/G cg11764359 chr7:65958608 NA -0.82 -13.74 -0.6 1.65e-34 Aortic root size; LIHC cis rs7772486 0.790 rs4075694 chr6:146251108 G/C cg05347473 chr6:146136440 FBXO30 -0.39 -6.13 -0.31 2.38e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9322817 0.691 rs9404586 chr6:105332814 A/G cg02098413 chr6:105308735 HACE1 0.4 7.57 0.38 3.47e-13 Thyroid stimulating hormone; LIHC cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg03721293 chr16:90014378 DEF8 0.37 6.45 0.33 3.91e-10 Skin colour saturation; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC trans rs7395662 0.571 rs12421145 chr11:48624725 C/A cg15704280 chr7:45808275 SEPT13 -0.47 -7.0 -0.35 1.35e-11 HDL cholesterol; LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg04267008 chr7:1944627 MAD1L1 -0.69 -11.45 -0.53 6.37e-26 Bipolar disorder and schizophrenia; LIHC cis rs2242116 0.592 rs6442039 chr3:46960797 C/G cg27129171 chr3:47204927 SETD2 0.45 6.57 0.33 1.87e-10 Birth weight; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg07424592 chr7:64974309 NA -0.46 -6.91 -0.35 2.31e-11 Calcium levels; LIHC cis rs763121 0.853 rs1056610 chr22:39080078 C/T cg06544989 chr22:39130855 UNC84B -0.37 -6.11 -0.31 2.78e-9 Menopause (age at onset); LIHC cis rs600806 0.751 rs7551176 chr1:109961965 C/T cg16275483 chr1:110013120 SYPL2 -0.47 -5.86 -0.3 1.09e-8 Intelligence (multi-trait analysis); LIHC cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg20607798 chr8:58055168 NA 0.5 6.26 0.32 1.15e-9 Developmental language disorder (linguistic errors); LIHC cis rs4888262 0.545 rs7184754 chr16:74667864 C/T cg01733217 chr16:74700730 RFWD3 0.86 17.51 0.69 1.88e-49 Testicular germ cell tumor; LIHC cis rs8072100 1.000 rs4794016 chr17:45725931 T/A cg19378624 chr17:45501242 LOC100272146;C17orf57 0.37 5.87 0.3 1.05e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs599083 0.530 rs576118 chr11:68177708 C/T cg16797656 chr11:68205561 LRP5 -0.49 -7.74 -0.39 1.12e-13 Bone mineral density (spine); LIHC cis rs2304069 0.550 rs216144 chr5:149445480 T/C cg22760475 chr5:149380129 HMGXB3;TIGD6 0.73 8.61 0.42 2.68e-16 HIV-1 control; LIHC cis rs6570726 0.791 rs11155432 chr6:145898761 T/C cg23711669 chr6:146136114 FBXO30 0.71 12.2 0.55 1.19e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs8017423 0.967 rs2401875 chr14:90688451 A/G cg04374321 chr14:90722782 PSMC1 0.71 13.52 0.59 1.13e-33 Mortality in heart failure; LIHC cis rs6963495 0.818 rs73190187 chr7:105164401 A/T cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs7103648 0.742 rs34937994 chr11:47389638 C/T cg20307385 chr11:47447363 PSMC3 0.87 12.93 0.57 2.01e-31 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg18357526 chr6:26021779 HIST1H4A 0.78 10.47 0.49 1.91e-22 Intelligence (multi-trait analysis); LIHC cis rs9309473 0.607 rs10198301 chr2:73581600 T/A cg20560298 chr2:73613845 ALMS1 -0.44 -6.86 -0.35 3.21e-11 Metabolite levels; LIHC cis rs11030122 0.702 rs10835311 chr11:3949027 G/T cg18678763 chr11:4115507 RRM1 -0.58 -8.44 -0.42 9.39e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs11671005 0.656 rs73066228 chr19:59013196 A/G cg25952890 chr19:58913133 NA 0.69 6.41 0.33 4.72e-10 Mean platelet volume; LIHC cis rs9660180 0.620 rs3817856 chr1:1663831 C/T cg13866156 chr1:1669148 SLC35E2 0.75 11.61 0.53 1.76e-26 Body mass index; LIHC cis rs4555082 0.874 rs113291192 chr14:105738181 C/T cg06808227 chr14:105710500 BRF1 -0.55 -7.17 -0.36 4.65e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs2050392 1.000 rs2480280 chr10:30696092 A/G cg25182066 chr10:30743637 MAP3K8 -0.44 -7.15 -0.36 5.42e-12 Inflammatory bowel disease; LIHC trans rs7618501 0.602 rs2240326 chr3:50128386 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.59 -9.46 -0.46 5.02e-19 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.579 rs2103938 chr10:38493998 T/G cg17219203 chr10:38645113 HSD17B7P2 -0.4 -5.8 -0.3 1.53e-8 Extrinsic epigenetic age acceleration; LIHC cis rs6840360 0.593 rs4696107 chr4:152606823 G/A cg22705602 chr4:152727874 NA -0.34 -7.05 -0.36 9.96e-12 Intelligence (multi-trait analysis); LIHC cis rs12824058 0.831 rs4759452 chr12:130812799 G/A cg26677194 chr12:130822605 PIWIL1 0.51 7.25 0.36 2.88e-12 Menopause (age at onset); LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.882 rs7633769 chr3:10020622 C/T cg08888203 chr3:10149979 C3orf24 0.45 5.88 0.3 9.54e-9 Alzheimer's disease; LIHC trans rs561341 1.000 rs498391 chr17:30328704 G/A cg20587970 chr11:113659929 NA -1.38 -11.98 -0.54 7.33e-28 Hip circumference adjusted for BMI; LIHC cis rs875971 0.965 rs10267430 chr7:65743023 G/T cg18876405 chr7:65276391 NA -0.37 -6.73 -0.34 7.14e-11 Aortic root size; LIHC cis rs908922 0.676 rs6587686 chr1:152528948 C/T cg20991723 chr1:152506922 NA 0.53 8.88 0.43 3.78e-17 Hair morphology; LIHC cis rs939574 0.799 rs1109867 chr2:220083453 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.96 -10.46 -0.49 2.05e-22 Platelet distribution width; LIHC trans rs11098499 0.863 rs13140409 chr4:120503460 A/G cg25214090 chr10:38739885 LOC399744 0.58 9.51 0.46 3.44e-19 Corneal astigmatism; LIHC cis rs4820539 0.966 rs2283803 chr22:23454881 G/A cg14186256 chr22:23484241 RTDR1 0.92 18.98 0.72 2.16e-55 Bone mineral density; LIHC cis rs67460515 0.892 rs7647374 chr3:160975576 T/A cg03342759 chr3:160939853 NMD3 -0.67 -10.11 -0.48 3.36e-21 Parkinson's disease; LIHC cis rs4819052 0.851 rs1056100 chr21:46678711 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 11.28 0.52 2.73e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12922317 0.964 rs12930612 chr16:12072203 G/A cg09319797 chr16:12061715 TNFRSF17 0.41 7.11 0.36 6.7e-12 Schizophrenia; LIHC cis rs7312933 0.558 rs4768399 chr12:42742696 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -8.17 -0.4 6.14e-15 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs765787 0.530 rs2413785 chr15:45530381 T/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.78 -0.3 1.71e-8 Uric acid levels; LIHC cis rs1008375 1.000 rs6848360 chr4:17634442 G/T cg02297831 chr4:17616191 MED28 0.51 7.95 0.39 2.76e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs57221529 0.766 rs4081847 chr5:574072 C/T cg09021430 chr5:549028 NA -0.45 -9.06 -0.44 1.05e-17 Lung disease severity in cystic fibrosis; LIHC cis rs2404602 0.647 rs12904149 chr15:77043652 A/C cg03037974 chr15:76606532 NA -0.6 -9.99 -0.48 8.46e-21 Blood metabolite levels; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC cis rs10089 1.000 rs72794392 chr5:127490061 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.6 0.34 1.59e-10 Ileal carcinoids; LIHC cis rs9814567 0.806 rs13076825 chr3:134317239 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.6 9.54 0.46 2.88e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3091242 0.934 rs686631 chr1:25719599 A/T cg02931644 chr1:25747376 RHCE 0.34 7.53 0.38 4.47e-13 Erythrocyte sedimentation rate; LIHC cis rs11677370 0.603 rs11696104 chr2:3849512 C/G cg17052675 chr2:3827356 NA -0.49 -6.34 -0.32 7.44e-10 Type 2 diabetes; LIHC cis rs9457247 0.765 rs10484531 chr6:167454434 G/A cg07741184 chr6:167504864 NA 0.31 7.21 0.36 3.65e-12 Crohn's disease; LIHC cis rs780096 0.506 rs8395 chr2:27715207 T/A cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.88 -0.3 9.73e-9 Total body bone mineral density; LIHC cis rs7546668 0.947 rs4645989 chr1:15850343 A/G cg11706911 chr1:15910989 AGMAT 0.44 6.82 0.35 4.03e-11 Glomerular filtration rate (creatinine); LIHC cis rs208520 0.661 rs4710566 chr6:66848538 G/A cg07460842 chr6:66804631 NA -0.74 -8.15 -0.4 7.08e-15 Exhaled nitric oxide output; LIHC cis rs6088590 0.965 rs6120730 chr20:33385102 G/C cg24642439 chr20:33292090 TP53INP2 0.78 10.57 0.5 8.71e-23 Coronary artery disease; LIHC cis rs7116495 1.000 rs552966 chr11:71788217 A/C cg26138937 chr11:71823887 C11orf51 -0.67 -6.76 -0.34 5.8200000000000003e-11 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg20607798 chr8:58055168 NA 0.71 8.55 0.42 4.28e-16 Developmental language disorder (linguistic errors); LIHC cis rs2637266 1.000 rs1907314 chr10:78337948 G/A cg18941641 chr10:78392320 NA 0.29 6.13 0.31 2.37e-9 Pulmonary function; LIHC cis rs6570726 0.967 rs373527 chr6:145801861 C/T cg23711669 chr6:146136114 FBXO30 0.49 8.64 0.42 2.14e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs17376456 0.877 rs10044066 chr5:93437580 T/C cg25358565 chr5:93447407 FAM172A 1.14 10.46 0.49 2.04e-22 Diabetic retinopathy; LIHC cis rs9296092 0.538 rs35381461 chr6:33519751 T/C cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs17685 0.672 rs56343450 chr7:75796235 C/T cg01364799 chr7:75623366 TMEM120A -0.52 -7.74 -0.39 1.13e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12971120 0.838 rs2241510 chr18:72180739 G/A cg25817165 chr18:72167213 CNDP2 -0.71 -12.2 -0.55 1.15e-28 Refractive error; LIHC cis rs68170813 0.559 rs78079372 chr7:106934548 T/G cg02696742 chr7:106810147 HBP1 -0.51 -5.91 -0.3 8.3e-9 Coronary artery disease; LIHC cis rs6788895 1.000 rs73005813 chr3:150525136 G/A cg09723797 chr3:150481914 SIAH2 0.57 6.76 0.34 6.06e-11 Breast cancer; LIHC cis rs2933343 0.700 rs876754 chr3:128627753 T/C cg24203234 chr3:128598194 ACAD9 0.44 6.2 0.32 1.61e-9 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14932796 chr17:55038330 COIL 0.47 7.05 0.36 9.85e-12 Pancreatic cancer; LIHC cis rs2976388 0.609 rs2376491 chr8:143790934 G/A cg06565975 chr8:143823917 SLURP1 0.33 6.28 0.32 1.01e-9 Urinary tract infection frequency; LIHC cis rs4919087 0.590 rs1253400 chr10:99049566 G/A cg25902810 chr10:99078978 FRAT1 -0.64 -7.02 -0.35 1.2e-11 Monocyte count; LIHC cis rs11191205 0.865 rs11191161 chr10:103726528 C/T cg15320455 chr10:103880129 LDB1 -0.88 -7.9 -0.39 3.86e-14 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.87 0.3 1.05e-8 Menopause (age at onset); LIHC cis rs929354 0.806 rs28446734 chr7:156996775 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.04 0.55 4.41e-28 Body mass index; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg19259030 chr15:76553926 ETFA;TYRO3P 0.43 6.08 0.31 3.13e-9 Hepatitis; LIHC cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg08067268 chr2:26466485 HADHB;HADHA -0.47 -6.73 -0.34 7.04e-11 Gut microbiome composition (summer); LIHC trans rs35110281 0.774 rs141521 chr21:44963686 G/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.14 0.32 2.26e-9 Mean corpuscular volume; LIHC cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 9.88 0.47 2e-20 Platelet count; LIHC cis rs7044106 0.708 rs2416760 chr9:123374639 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.96 0.51 3.72e-24 Hip circumference adjusted for BMI; LIHC cis rs6442522 0.606 rs12633820 chr3:15494002 C/T cg16303742 chr3:15540471 COLQ 0.38 6.3 0.32 9.04e-10 Uric acid levels; LIHC trans rs116095464 0.558 rs2288459 chr5:231143 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs9393692 0.875 rs6939589 chr6:26289203 C/T cg13736514 chr6:26305472 NA 0.38 6.44 0.33 4.13e-10 Educational attainment; LIHC cis rs4450131 0.618 rs10736889 chr10:126338657 C/T cg20435097 chr10:126320824 FAM53B 0.62 12.04 0.55 4.62e-28 White blood cell count (basophil); LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.72 -0.34 7.62e-11 Lymphocyte counts; LIHC cis rs875971 0.862 rs10276077 chr7:65728411 A/G cg11764359 chr7:65958608 NA -0.84 -14.87 -0.63 6.54e-39 Aortic root size; LIHC cis rs858239 0.539 rs6461694 chr7:23187779 G/A cg18081818 chr7:23246105 NA -0.39 -5.75 -0.3 1.95e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs6545883 0.965 rs9989775 chr2:61761774 A/G cg15711740 chr2:61764176 XPO1 -0.44 -6.14 -0.32 2.27e-9 Tuberculosis; LIHC cis rs55665837 0.665 rs11023273 chr11:14630819 G/A cg00085434 chr11:14927489 NA 0.43 6.05 0.31 3.73e-9 Vitamin D levels; LIHC cis rs7772486 0.686 rs6570701 chr6:145954090 A/G cg23711669 chr6:146136114 FBXO30 0.69 12.59 0.56 4.11e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs2637266 1.000 rs6480827 chr10:78356333 T/G cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC trans rs7615952 0.932 rs6438948 chr3:125650045 A/T cg07211511 chr3:129823064 LOC729375 0.71 9.2 0.45 3.6e-18 Blood pressure (smoking interaction); LIHC cis rs6450176 0.625 rs56193151 chr5:53287790 C/T ch.5.1024479R chr5:53302184 ARL15 -0.87 -15.67 -0.65 4.15e-42 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs523522 0.962 rs4767904 chr12:120930798 T/G cg12219531 chr12:120966889 COQ5 0.66 13.11 0.58 4.19e-32 High light scatter reticulocyte count; LIHC cis rs875971 0.545 rs7787063 chr7:65628999 G/A cg11764359 chr7:65958608 NA 0.51 7.04 0.36 1.08e-11 Aortic root size; LIHC cis rs600806 0.815 rs4970758 chr1:109979617 A/G cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.16 -0.36 4.83e-12 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.904 rs7503705 chr17:37669704 A/G cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC cis rs611744 0.905 rs610891 chr8:109161003 C/T cg21045802 chr8:109455806 TTC35 -0.48 -8.08 -0.4 1.12e-14 Dupuytren's disease; LIHC cis rs4474465 0.790 rs6592784 chr11:78234790 C/T cg27205649 chr11:78285834 NARS2 0.41 6.17 0.32 1.91e-9 Alzheimer's disease (survival time); LIHC trans rs916888 0.821 rs199505 chr17:44859410 A/G cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg24549020 chr5:56110836 MAP3K1 0.49 6.21 0.32 1.55e-9 Type 2 diabetes; LIHC cis rs1707322 0.827 rs12125508 chr1:46246010 A/G cg03146154 chr1:46216737 IPP 0.53 8.71 0.43 1.33e-16 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs140364877 1 rs140364877 chr7:1885178 C/T cg14004847 chr7:1930337 MAD1L1 -0.43 -6.19 -0.32 1.73e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs288342 0.796 rs288347 chr2:183667642 C/G cg02625481 chr2:183667124 NA -0.31 -6.18 -0.32 1.8e-9 Recurrent major depressive disorder; LIHC cis rs9660992 0.762 rs1668871 chr1:205237137 T/C cg21545522 chr1:205238299 TMCC2 0.31 6.45 0.33 3.91e-10 Mean corpuscular volume;Mean platelet volume; LIHC trans rs10805346 0.505 rs35995899 chr4:10112862 T/C cg06175025 chr14:78082992 SPTLC2 -0.47 -6.88 -0.35 2.79e-11 Urate levels in overweight individuals;Urate levels in obese individuals; LIHC cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg15691649 chr6:25882328 NA -0.42 -6.55 -0.33 2.08e-10 Height; LIHC cis rs79839061 0.563 rs55728587 chr4:843674 G/A cg07828340 chr4:882639 GAK 0.79 6.02 0.31 4.38e-9 Intelligence (multi-trait analysis); LIHC cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg03060546 chr3:49711283 APEH 0.39 5.85 0.3 1.15e-8 Menarche (age at onset); LIHC cis rs62380364 0.602 rs665324 chr5:88055517 T/C cg22951263 chr5:87985283 NA -0.4 -6.85 -0.35 3.42e-11 Intelligence (multi-trait analysis); LIHC cis rs752010 0.684 rs10789402 chr1:42084649 A/G cg06885757 chr1:42089581 HIVEP3 0.31 6.41 0.33 4.87e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs9457247 0.935 rs401260 chr6:167405888 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs9914988 0.832 rs34901720 chr17:27179518 A/G cg20469991 chr17:27169893 C17orf63 -0.55 -6.44 -0.33 4.01e-10 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs311392 0.554 rs311390 chr8:55102401 G/A cg11783602 chr8:55087084 NA -0.3 -6.18 -0.32 1.82e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs1190552 0.761 rs1212691 chr14:102893272 T/C cg10241871 chr14:102965420 TECPR2 0.41 6.04 0.31 3.94e-9 Blood protein levels; LIHC cis rs2070488 0.804 rs1817364 chr3:38474513 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.74 12.31 0.55 4.45e-29 Electrocardiographic conduction measures; LIHC cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs1499614 0.831 rs3800822 chr7:66147149 A/G cg05590025 chr7:65112418 INTS4L2 0.56 6.09 0.31 3.04e-9 Gout; LIHC cis rs9790314 0.967 rs336541 chr3:161056698 A/C cg04691961 chr3:161091175 C3orf57 -0.42 -6.64 -0.34 1.25e-10 Morning vs. evening chronotype; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05792827 chr1:213224765 RPS6KC1 -0.49 -6.21 -0.32 1.57e-9 Systolic blood pressure; LIHC cis rs10861342 0.892 rs7488014 chr12:105657527 C/T cg23923672 chr12:105501055 KIAA1033 0.59 6.91 0.35 2.4e-11 IgG glycosylation; LIHC cis rs924607 1.000 rs1697978 chr5:642829 A/G cg24163568 chr5:669837 TPPP 0.39 8.1 0.4 1.01e-14 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs9303401 0.659 rs7210700 chr17:56668186 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.34 0.58 5.79e-33 Cognitive test performance; LIHC cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg12311346 chr5:56204834 C5orf35 -0.58 -7.52 -0.38 4.84e-13 Initial pursuit acceleration; LIHC cis rs11098499 0.863 rs3822192 chr4:120445720 A/C cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.68e-27 Corneal astigmatism; LIHC cis rs4901869 0.966 rs1820557 chr14:59334863 C/G cg02291164 chr14:59296302 NA 0.48 6.12 0.31 2.6e-9 Panic disorder; LIHC cis rs1962636 1 rs1962636 chr16:22064395 A/C cg04454073 chr16:22207163 NA 0.34 5.87 0.3 1.04e-8 Schizophrenia; LIHC cis rs11212260 0.655 rs11212241 chr11:107313894 C/T cg25435332 chr11:107328525 CWF19L2 0.82 8.32 0.41 2.13e-15 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16725865 chr1:92546135 BTBD8 0.45 6.82 0.35 4.1e-11 Pancreatic cancer; LIHC cis rs1395 1.000 rs1275538 chr2:27441397 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -5.76 -0.3 1.88e-8 Blood metabolite levels; LIHC cis rs6598955 0.724 rs12754536 chr1:26639605 T/C cg00852783 chr1:26633632 UBXN11 0.52 8.6 0.42 2.94e-16 Obesity-related traits; LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg13012494 chr21:47604986 C21orf56 0.37 5.76 0.3 1.87e-8 Testicular germ cell tumor; LIHC cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg11764359 chr7:65958608 NA 0.69 9.4 0.45 8.19e-19 Aortic root size; LIHC cis rs875971 0.545 rs7783889 chr7:65748353 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.49 0.38 5.75e-13 Aortic root size; LIHC cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg05564831 chr3:52568323 NT5DC2 0.35 5.75 0.3 1.99e-8 Electroencephalogram traits; LIHC cis rs599083 0.530 rs546803 chr11:68186392 C/T cg16797656 chr11:68205561 LRP5 -0.52 -7.98 -0.4 2.2e-14 Bone mineral density (spine); LIHC cis rs921968 0.643 rs4674319 chr2:219510320 C/T cg02985541 chr2:219472218 PLCD4 0.41 7.21 0.36 3.65e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs11098499 0.954 rs6849561 chr4:120409694 C/G cg09307838 chr4:120376055 NA -0.77 -12.11 -0.55 2.55e-28 Corneal astigmatism; LIHC cis rs9914988 0.606 rs968726 chr17:27194634 A/G cg20469991 chr17:27169893 C17orf63 -0.49 -6.21 -0.32 1.53e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7940866 0.801 rs10894300 chr11:130845943 A/G cg12179176 chr11:130786555 SNX19 0.64 9.25 0.45 2.44e-18 Schizophrenia; LIHC cis rs9905704 0.647 rs11079367 chr17:57009024 A/G cg05425664 chr17:57184151 TRIM37 -0.44 -6.16 -0.32 2e-9 Testicular germ cell tumor; LIHC cis rs317689 0.690 rs595348 chr12:69638610 T/C cg19645103 chr12:69753606 YEATS4 -0.44 -5.81 -0.3 1.44e-8 Response to diuretic therapy; LIHC cis rs922107 0.738 rs12729983 chr1:90046593 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.77 -0.39 9.31e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7614311 0.681 rs2241822 chr3:63965304 A/G cg22134162 chr3:63841271 THOC7 -0.55 -6.05 -0.31 3.74e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs4853012 0.793 rs6723185 chr2:74344884 T/A cg01017244 chr2:74357527 NA 0.63 11.3 0.52 2.33e-25 Gestational age at birth (maternal effect); LIHC cis rs2404602 0.692 rs12910734 chr15:77149931 A/G cg23625390 chr15:77176239 SCAPER 0.36 5.84 0.3 1.2e-8 Blood metabolite levels; LIHC cis rs11677370 0.574 rs10190477 chr2:3862738 A/G cg17052675 chr2:3827356 NA 0.49 6.28 0.32 1.01e-9 Type 2 diabetes; LIHC cis rs4713118 0.513 rs149944 chr6:28002818 C/T cg16479474 chr6:28041457 NA 0.38 6.24 0.32 1.29e-9 Parkinson's disease; LIHC cis rs10791323 0.569 rs10791328 chr11:133713730 A/G cg06766960 chr11:133703094 NA -0.66 -11.06 -0.51 1.69e-24 Childhood ear infection; LIHC cis rs34330 0.562 rs10492235 chr12:12851339 T/G cg04607235 chr12:12878440 APOLD1 -0.74 -8.95 -0.44 2.37e-17 Systemic lupus erythematosus; LIHC cis rs875971 0.638 rs6460305 chr7:66060408 G/A cg11764359 chr7:65958608 NA -0.73 -10.96 -0.51 3.81e-24 Aortic root size; LIHC cis rs875971 0.862 rs4718319 chr7:65652784 C/A cg18252515 chr7:66147081 NA 0.42 5.77 0.3 1.79e-8 Aortic root size; LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg07133347 chr1:107600762 PRMT6 0.42 6.24 0.32 1.31e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs611744 0.647 rs689275 chr8:109241822 T/C cg18478394 chr8:109455254 TTC35 0.4 6.89 0.35 2.66e-11 Dupuytren's disease; LIHC trans rs1814175 0.618 rs1851843 chr11:50021846 T/C cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC trans rs2727020 0.823 rs7102374 chr11:49261795 G/A cg15704280 chr7:45808275 SEPT13 0.77 11.66 0.53 1.15e-26 Coronary artery disease; LIHC cis rs4820539 1.000 rs756631 chr22:23463183 A/G cg21100191 chr22:23484243 RTDR1 0.9 16.17 0.66 4.58e-44 Bone mineral density; LIHC cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg15691649 chr6:25882328 NA 0.76 10.63 0.5 5.45e-23 Blood metabolite levels; LIHC cis rs9394841 0.667 rs3827633 chr6:41759846 A/C cg17623882 chr6:41773611 USP49 -0.44 -5.85 -0.3 1.15e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs1215050 0.740 rs783945 chr4:99014394 G/A cg05340658 chr4:99064831 C4orf37 -0.4 -6.27 -0.32 1.08e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs79149102 0.579 rs7168638 chr15:75280826 T/C cg09165964 chr15:75287851 SCAMP5 -0.59 -7.8 -0.39 7.37e-14 Lung cancer; LIHC cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg20295408 chr7:1910781 MAD1L1 -0.5 -7.36 -0.37 1.36e-12 Bipolar disorder and schizophrenia; LIHC cis rs9926296 0.572 rs2376878 chr16:89885161 G/A cg27121462 chr16:89883253 FANCA 0.48 7.99 0.4 2.05e-14 Vitiligo; LIHC cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg21448741 chr8:58168803 NA 0.33 6.64 0.34 1.26e-10 Developmental language disorder (linguistic errors); LIHC cis rs6564851 0.545 rs12149068 chr16:81252903 T/G cg00908271 chr16:81254010 PKD1L2 -0.36 -7.57 -0.38 3.44e-13 Carotenoid and tocopherol levels; LIHC cis rs910316 0.737 rs28687415 chr14:75495482 T/C cg11812906 chr14:75593930 NEK9 0.74 13.64 0.59 3.84e-34 Height; LIHC cis rs1801251 0.928 rs737028 chr2:233640750 T/C cg08000102 chr2:233561755 GIGYF2 0.76 11.41 0.52 9.33e-26 Coronary artery disease; LIHC cis rs55702914 0.839 rs2059922 chr2:198188903 C/G cg10820045 chr2:198174542 NA -0.41 -5.99 -0.31 5.17e-9 Major depression and alcohol dependence; LIHC cis rs62117911 1 rs62117911 chr19:16241886 G/A cg07665718 chr19:16244068 HSH2D;RAB8A 0.53 6.77 0.34 5.59e-11 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs7618501 1.000 rs1491986 chr3:49739086 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.48 -0.73 2.21e-57 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg21747090 chr2:27597821 SNX17 -0.44 -6.64 -0.34 1.21e-10 Total body bone mineral density; LIHC cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg08067268 chr2:26466485 HADHB;HADHA 0.46 6.82 0.35 4.1e-11 Gut microbiome composition (summer); LIHC cis rs1400745 0.729 rs28472856 chr14:35332157 C/T cg16230307 chr14:35515116 FAM177A1 0.38 6.19 0.32 1.71e-9 Monocyte count; LIHC cis rs2153535 0.580 rs7341382 chr6:8470549 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs5758659 0.714 rs2413668 chr22:42505841 G/A cg19513890 chr22:42538836 CYP2D7P1 0.41 8.28 0.41 2.85e-15 Cognitive function; LIHC cis rs875971 0.545 rs75577046 chr7:65958716 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 7.02 0.35 1.21e-11 Aortic root size; LIHC cis rs2236918 0.710 rs1776138 chr1:242027075 G/A cg17736920 chr1:242011382 EXO1 0.42 6.28 0.32 1.03e-9 Menopause (age at onset); LIHC trans rs6952808 0.964 rs6945719 chr7:1932688 G/A cg04565464 chr8:145669602 NFKBIL2 0.39 6.14 0.32 2.26e-9 Bipolar disorder and schizophrenia; LIHC cis rs2842992 0.692 rs9347342 chr6:160193129 T/C cg19482086 chr6:160211437 TCP1;MRPL18 0.66 12.27 0.55 6.48e-29 Age-related macular degeneration (geographic atrophy); LIHC trans rs1432089 0.773 rs28376254 chr4:171785696 G/A cg02328223 chr3:127541927 MGLL -0.41 -6.04 -0.31 3.98e-9 Endometriosis; LIHC cis rs9921222 0.521 rs78867928 chr16:368986 C/T cg00101154 chr16:420108 MRPL28 -0.59 -8.08 -0.4 1.14e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs9457247 0.646 rs239934 chr6:167412048 G/A cg07741184 chr6:167504864 NA 0.29 6.76 0.34 5.98e-11 Crohn's disease; LIHC cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.33e-12 Bipolar disorder; LIHC cis rs17685 0.672 rs6465011 chr7:75811297 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.88 0.35 2.9e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4474465 1.000 rs11602360 chr11:78179336 A/G cg02023728 chr11:77925099 USP35 -0.32 -5.92 -0.3 8.02e-9 Alzheimer's disease (survival time); LIHC cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg09033563 chr22:24373618 LOC391322 -0.45 -6.1 -0.31 2.82e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs4698048 0.510 rs12509714 chr4:10107091 C/G cg06175025 chr14:78082992 SPTLC2 -0.41 -6.08 -0.31 3.17e-9 Skin aging (microtopography measurement); LIHC cis rs9910055 0.530 rs11652651 chr17:42302907 A/G cg08499158 chr17:42289980 UBTF 0.47 7.64 0.38 2.18e-13 Total body bone mineral density; LIHC cis rs8067545 0.717 rs7207625 chr17:20001612 G/A cg13482628 chr17:19912719 NA 0.49 7.98 0.4 2.24e-14 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00593699 chr11:472782 PTDSS2 0.41 6.1 0.31 2.83e-9 Longevity; LIHC cis rs17376456 0.877 rs17083455 chr5:93446380 A/C cg25358565 chr5:93447407 FAM172A 1.15 10.7 0.5 3.08e-23 Diabetic retinopathy; LIHC cis rs875971 0.619 rs10278371 chr7:66051540 C/A cg14393609 chr7:65229607 NA -0.41 -6.32 -0.32 8.1e-10 Aortic root size; LIHC cis rs916888 0.773 rs199447 chr17:44812188 C/T cg01570182 chr17:44337453 NA 1.01 10.03 0.48 6.25e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7523273 0.565 rs2761420 chr1:207889368 G/T cg22525895 chr1:207977042 MIR29B2 -0.53 -7.94 -0.39 3e-14 Schizophrenia; LIHC cis rs11864453 0.713 rs9926156 chr16:72142895 G/C cg01557791 chr16:72042693 DHODH -0.46 -7.6 -0.38 2.8e-13 Fibrinogen levels; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg24930797 chr15:66083595 DENND4A -0.54 -6.06 -0.31 3.58e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs9916302 0.904 rs1077715 chr17:37683548 A/T cg00129232 chr17:37814104 STARD3 -0.42 -6.79 -0.34 4.83e-11 Glomerular filtration rate (creatinine); LIHC cis rs12765878 1.000 rs11191846 chr10:105649813 A/G cg11005552 chr10:105648138 OBFC1 0.38 6.12 0.31 2.63e-9 Coronary artery disease; LIHC cis rs7116495 0.867 rs513292 chr11:71573771 C/G cg26138937 chr11:71823887 C11orf51 0.71 6.88 0.35 2.81e-11 Severe influenza A (H1N1) infection; LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs7927771 1.000 rs12418852 chr11:47868853 C/G cg20307385 chr11:47447363 PSMC3 -0.45 -5.89 -0.3 9.14e-9 Subjective well-being; LIHC cis rs6977660 0.714 rs17141884 chr7:19790280 A/G cg07541023 chr7:19748670 TWISTNB -0.48 -7.24 -0.36 2.96e-12 Thyroid stimulating hormone; LIHC cis rs7208859 0.673 rs11655623 chr17:29162173 T/C cg14067834 chr17:29058358 SUZ12P 0.66 6.55 0.33 2.18e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9640161 0.830 rs35840727 chr7:150063204 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.09 -0.4 1.08e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs3849570 1.000 rs3772882 chr3:81808602 C/A cg07356753 chr3:81810745 GBE1 -0.6 -8.21 -0.41 4.66e-15 Waist circumference;Body mass index; LIHC cis rs8077889 1.000 rs17742905 chr17:41891143 C/A cg26893861 chr17:41843967 DUSP3 1.0 11.01 0.51 2.48e-24 Triglycerides; LIHC cis rs6500602 0.964 rs13335685 chr16:4469284 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 5.98 0.31 5.71e-9 Schizophrenia; LIHC cis rs12368653 0.693 rs2640610 chr12:58037435 T/A cg12615879 chr12:58013172 SLC26A10 0.34 6.84 0.35 3.74e-11 Multiple sclerosis; LIHC cis rs7106204 0.748 rs36092013 chr11:24211987 C/T ch.11.24196551F chr11:24239977 NA 0.76 10.13 0.48 2.98e-21 Response to Homoharringtonine (cytotoxicity); LIHC cis rs11233413 0.874 rs3793987 chr11:82704968 A/T cg24227371 chr11:82718527 RAB30 -0.32 -6.79 -0.34 4.88e-11 Economic and political preferences (feminism/equality); LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg11494091 chr17:61959527 GH2 0.36 6.06 0.31 3.56e-9 Height; LIHC cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg06238570 chr21:40685208 BRWD1 -0.4 -6.38 -0.33 5.74e-10 Menarche (age at onset); LIHC cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs763121 0.819 rs5757169 chr22:39003495 G/A cg14440974 chr22:39074834 NA -0.36 -5.97 -0.31 5.9e-9 Menopause (age at onset); LIHC cis rs7520050 0.931 rs6686134 chr1:46378268 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.73 0.3 2.16e-8 Red blood cell count;Reticulocyte count; LIHC cis rs9916302 0.861 rs8081033 chr17:37506650 A/G cg00129232 chr17:37814104 STARD3 0.38 6.08 0.31 3.27e-9 Glomerular filtration rate (creatinine); LIHC trans rs2363709 1.000 rs4241438 chr3:67425727 A/G cg25028035 chr6:42016671 CCND3 -0.84 -6.07 -0.31 3.44e-9 IgE levels; LIHC trans rs10448080 0.959 rs4732873 chr8:28601554 A/C cg07469555 chr8:22423055 SORBS3 0.45 6.14 0.32 2.35e-9 Height; LIHC cis rs4631830 0.832 rs2337711 chr10:51504604 C/T cg20129853 chr10:51489980 NA 0.42 9.0 0.44 1.63e-17 Prostate-specific antigen levels; LIHC cis rs12477438 0.765 rs6722164 chr2:99561527 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.48 -0.38 6.16e-13 Chronic sinus infection; LIHC cis rs9918079 0.560 rs10008975 chr4:15624571 C/T cg16509355 chr4:15471240 CC2D2A -0.45 -7.07 -0.36 8.72e-12 Obesity-related traits; LIHC cis rs9381040 0.701 rs4711658 chr6:41162891 C/T cg04346459 chr6:41068666 NFYA;LOC221442 0.37 6.35 0.32 6.78e-10 Alzheimer's disease (late onset); LIHC cis rs16912285 0.585 rs11027807 chr11:24346556 G/T ch.11.24196551F chr11:24239977 NA 0.68 7.75 0.39 1.09e-13 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs992157 0.560 rs10932763 chr2:219085863 G/C cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.23 -0.55 8.76e-29 Colorectal cancer; LIHC cis rs801193 1.000 rs2055682 chr7:66260289 A/G cg11764359 chr7:65958608 NA 0.69 10.21 0.48 1.52e-21 Aortic root size; LIHC cis rs5753618 0.561 rs2040533 chr22:31679110 G/C cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs11758351 1.000 rs2143347 chr6:26198494 C/T cg03854865 chr6:26224070 HIST1H3E 0.62 6.99 0.35 1.46e-11 Gout;Renal underexcretion gout; LIHC cis rs17666538 0.710 rs7834337 chr8:655828 A/G cg23958373 chr8:599963 NA 0.73 6.53 0.33 2.41e-10 IgG glycosylation; LIHC cis rs12144094 0.882 rs12127451 chr1:120227630 C/A cg20995928 chr1:120229863 NA 0.37 6.26 0.32 1.16e-9 Height; LIHC cis rs473651 0.935 rs540636 chr2:239358341 T/C cg21699342 chr2:239360505 ASB1 0.36 6.96 0.35 1.73e-11 Multiple system atrophy; LIHC cis rs1355223 1.000 rs1355221 chr11:34758609 G/A cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.61 -0.34 1.5e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9914988 0.943 rs4794836 chr17:27082710 C/G cg20469991 chr17:27169893 C17orf63 0.5 6.07 0.31 3.44e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs35306767 0.812 rs1013504 chr10:952816 T/C cg26597838 chr10:835615 NA 1.51 14.64 0.62 5.14e-38 Eosinophil percentage of granulocytes; LIHC cis rs4474465 0.833 rs6592792 chr11:78271614 A/C cg02023728 chr11:77925099 USP35 -0.37 -6.21 -0.32 1.55e-9 Alzheimer's disease (survival time); LIHC cis rs17685 0.623 rs7782808 chr7:75768645 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07791762 chr19:17323290 MYO9B 0.37 6.12 0.31 2.63e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2576037 0.545 rs9948405 chr18:44494527 C/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.8 -0.3 1.5e-8 Personality dimensions; LIHC cis rs1348850 0.632 rs12616288 chr2:178503813 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.81 0.39 7.16e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2180341 1.000 rs2144742 chr6:127595786 C/A cg24812749 chr6:127587940 RNF146 1.05 15.71 0.65 2.87e-42 Breast cancer; LIHC cis rs10744422 1.000 rs7138398 chr12:123341833 G/C cg07706471 chr12:123319906 HIP1R -0.62 -8.2 -0.41 4.94e-15 Schizophrenia; LIHC cis rs2455799 0.613 rs9848007 chr3:15852593 T/A cg12698662 chr3:15914712 MIR563 -0.39 -7.15 -0.36 5.35e-12 Mean platelet volume; LIHC cis rs3540 0.533 rs2256110 chr15:90971036 T/C cg22089800 chr15:90895588 ZNF774 0.58 8.04 0.4 1.49e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs7520050 0.966 rs10789487 chr1:46420221 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.41 5.92 0.3 7.76e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11628318 0.614 rs7143783 chr14:103128751 A/G cg23461800 chr14:103021989 NA 0.45 6.31 0.32 8.6e-10 Platelet count; LIHC cis rs2749592 0.531 rs1208559 chr10:38221370 T/C cg25427524 chr10:38739819 LOC399744 0.65 12.97 0.57 1.46e-31 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14990712 chr19:4055085 ZBTB7A 0.45 6.77 0.34 5.53e-11 Bilirubin levels; LIHC cis rs11098699 0.821 rs2047584 chr4:124232182 A/T cg09941581 chr4:124220074 SPATA5 0.33 6.55 0.33 2.07e-10 Mosquito bite size; LIHC cis rs2108622 0.727 rs62106155 chr19:15980360 G/C cg13772218 chr19:15982569 NA 0.37 7.82 0.39 6.59e-14 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06446895 chr17:79829189 ARHGDIA -0.46 -6.6 -0.34 1.61e-10 Cognitive function; LIHC trans rs634534 0.561 rs655744 chr11:65776585 G/T cg17712092 chr4:129076599 LARP1B -0.72 -12.79 -0.57 6.97e-31 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs12752401 0.717 rs34542611 chr1:103028047 C/T cg17681729 chr19:740608 PALM 0.45 6.29 0.32 9.58e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs4268898 0.795 rs12470303 chr2:24619883 C/T cg06627628 chr2:24431161 ITSN2 -0.48 -6.87 -0.35 2.96e-11 Asthma; LIHC cis rs986417 0.901 rs11627533 chr14:61037801 C/T cg27398547 chr14:60952738 C14orf39 0.7 7.84 0.39 5.97e-14 Gut microbiota (bacterial taxa); LIHC cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg06634786 chr22:41940651 POLR3H -0.73 -8.25 -0.41 3.57e-15 Vitiligo; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg01423147 chr1:89458345 RBMXL1;CCBL2 -0.42 -6.04 -0.31 4.11e-9 Eotaxin levels; LIHC cis rs9814567 0.964 rs9833753 chr3:134213665 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.96 -0.31 6.34e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12477438 0.798 rs4622780 chr2:99631760 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.53 -0.53 3.3e-26 Chronic sinus infection; LIHC cis rs7534824 0.625 rs61782081 chr1:101507074 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.67 7.46 0.37 7.21e-13 Refractive astigmatism; LIHC cis rs1144333 0.850 rs1144342 chr1:76284364 A/G cg22875332 chr1:76189707 ACADM -0.42 -6.74 -0.34 6.7e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg05590025 chr7:65112418 INTS4L2 -0.63 -6.96 -0.35 1.7e-11 Diabetic kidney disease; LIHC cis rs1059312 0.932 rs4760592 chr12:129287149 G/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -14.36 -0.61 6.62e-37 Systemic lupus erythematosus; LIHC cis rs2242116 0.796 rs4683296 chr3:46973820 G/C cg16586182 chr3:47516702 SCAP 0.4 6.71 0.34 8.29e-11 Birth weight; LIHC cis rs4728302 0.807 rs10226267 chr7:133601862 G/A cg10665199 chr7:133106180 EXOC4 0.39 6.83 0.35 3.86e-11 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs4589502 0.925 rs4259997 chr15:67153310 A/G cg12317470 chr15:67143691 NA -0.69 -8.75 -0.43 9.82e-17 Lung cancer (smoking interaction); LIHC cis rs9640161 0.711 rs3735170 chr7:150034184 T/C cg27494647 chr7:150038898 RARRES2 0.34 6.09 0.31 2.96e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs7188697 0.922 rs37034 chr16:58551360 C/G cg02549819 chr16:58548995 SETD6 -0.51 -7.88 -0.39 4.53e-14 QT interval; LIHC cis rs986417 0.892 rs8017336 chr14:60798682 G/A cg27398547 chr14:60952738 C14orf39 -0.72 -7.62 -0.38 2.47e-13 Gut microbiota (bacterial taxa); LIHC cis rs7772486 0.875 rs1412081 chr6:146409733 A/G cg23711669 chr6:146136114 FBXO30 0.57 9.77 0.47 4.67e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs7568458 0.684 rs60012532 chr2:85752474 A/C cg02493740 chr2:85810744 VAMP5 -0.46 -7.79 -0.39 7.95e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs8141529 0.644 rs5752795 chr22:29178820 T/C cg02153584 chr22:29168773 CCDC117 0.56 9.15 0.44 5.27e-18 Lymphocyte counts; LIHC cis rs12048904 0.619 rs10783153 chr1:101328230 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.47 6.88 0.35 2.95e-11 Multiple sclerosis; LIHC cis rs7106204 0.748 rs4598670 chr11:24236524 G/A ch.11.24196551F chr11:24239977 NA 0.81 11.95 0.54 9.87e-28 Response to Homoharringtonine (cytotoxicity); LIHC cis rs11792861 0.926 rs7855282 chr9:111802614 T/A cg05043794 chr9:111880884 C9orf5 -0.29 -6.75 -0.34 6.35e-11 Menarche (age at onset); LIHC trans rs10117734 0.632 rs10974525 chr9:4417406 A/G cg04219946 chr7:87104724 ABCB4 -0.38 -6.35 -0.32 6.96e-10 Parental extreme longevity (95 years and older); LIHC cis rs5769765 0.908 rs4824109 chr22:50271460 T/C cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs7554547 0.667 rs2336377 chr1:11949970 A/G cg07603449 chr1:11986842 KIAA2013 0.36 6.22 0.32 1.49e-9 Nonsyndromic cleft lip with cleft palate; LIHC cis rs9948 1.000 rs58147284 chr2:97508082 G/C cg01990225 chr2:97406019 LMAN2L -0.59 -5.99 -0.31 5.19e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs67460515 0.563 rs9876142 chr3:160780968 A/G cg17135325 chr3:160939158 NMD3 -0.49 -6.53 -0.33 2.38e-10 Parkinson's disease; LIHC cis rs5769765 0.837 rs8142737 chr22:50291889 T/C cg02269571 chr22:50332266 NA -0.6 -8.57 -0.42 3.49e-16 Schizophrenia; LIHC cis rs2425143 1.000 rs6060578 chr20:34305445 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -5.74 -0.3 2.09e-8 Blood protein levels; LIHC cis rs2033908 0.619 rs10765994 chr11:12850819 A/G cg25843174 chr11:12811716 TEAD1 0.33 7.48 0.38 6.18e-13 Sitting height ratio; LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg00091569 chr3:40428383 ENTPD3 0.41 6.98 0.35 1.5e-11 Renal cell carcinoma; LIHC cis rs9858542 0.953 rs34588335 chr3:49407660 G/C cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs34779708 0.931 rs35136660 chr10:35385973 C/A cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9911578 1.000 rs12952832 chr17:56906254 T/C cg12560992 chr17:57184187 TRIM37 0.96 17.4 0.69 5.04e-49 Intelligence (multi-trait analysis); LIHC cis rs8081692 1 rs8081692 chr17:38154595 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.17 -0.44 4.45e-18 Neutrophil count; LIHC cis rs1443512 0.773 rs2366146 chr12:54331002 G/A cg17410650 chr12:54324560 NA -0.4 -7.22 -0.36 3.4e-12 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs4819052 1.000 rs2838847 chr21:46670958 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 9.8 0.47 3.71e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1568889 0.838 rs12273631 chr11:28042135 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.66 13.64 0.59 4.1e-34 Bipolar disorder; LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 11.07 0.51 1.46e-24 Prudent dietary pattern; LIHC cis rs9948 0.655 rs17119591 chr2:97435557 G/A cg01990225 chr2:97406019 LMAN2L -0.82 -6.36 -0.33 6.61e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg25894440 chr7:65020034 NA 0.53 6.15 0.32 2.16e-9 Diabetic kidney disease; LIHC trans rs10242455 0.571 rs73713595 chr7:99326659 G/A cg09045935 chr12:6379348 NA 0.73 6.07 0.31 3.48e-9 Blood metabolite levels; LIHC cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg07424592 chr7:64974309 NA 0.83 9.5 0.46 3.78e-19 Diabetic kidney disease; LIHC cis rs507080 0.733 rs541631 chr11:118571023 A/G cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17017152 chr1:61547389 NFIA 0.47 6.15 0.32 2.12e-9 Lung function (FEV1/FVC); LIHC cis rs2576037 0.583 rs9916891 chr18:44493521 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.81 -0.3 1.46e-8 Personality dimensions; LIHC trans rs214034 0.825 rs7566260 chr2:17875837 T/C cg09061216 chr1:1558936 MIB2 0.51 6.04 0.31 4.01e-9 Response to amphetamines; LIHC cis rs12368653 0.651 rs2277326 chr12:58202419 A/C cg04478727 chr12:58166393 METTL1;FAM119B 0.49 6.7 0.34 8.71e-11 Multiple sclerosis; LIHC cis rs7542375 0.507 rs2784270 chr1:221094967 C/T cg16008148 chr1:221062819 NA -0.3 -6.47 -0.33 3.42e-10 Obesity-related traits; LIHC cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg21782813 chr7:2030301 MAD1L1 0.45 7.8 0.39 7.44e-14 Bipolar disorder and schizophrenia; LIHC cis rs1799949 0.860 rs8176279 chr17:41210396 A/C cg05368731 chr17:41323189 NBR1 0.69 11.41 0.52 9.23e-26 Menopause (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02873242 chr5:154134737 LARP1 0.49 6.24 0.32 1.3e-9 Hepatitis; LIHC cis rs7107174 0.892 rs4291702 chr11:78001248 C/T cg02023728 chr11:77925099 USP35 0.45 8.79 0.43 7.27e-17 Testicular germ cell tumor; LIHC cis rs6876835 0.511 rs56874700 chr5:6597898 A/G cg04204831 chr5:6583394 LOC255167 0.42 6.51 0.33 2.65e-10 Visceral fat; LIHC cis rs1790761 0.692 rs611663 chr11:67312221 C/T cg01069141 chr11:67398826 TBX10;NUDT8 0.37 6.6 0.34 1.56e-10 Mean corpuscular volume; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg07755735 chr2:20870362 GDF7 -0.44 -9.08 -0.44 8.71e-18 Abdominal aortic aneurysm; LIHC cis rs11711311 0.869 rs1026364 chr3:113370010 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.36 -6.45 -0.33 3.73e-10 IgG glycosylation; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01430372 chr17:38976870 TMEM99;KRT10 0.24 6.34 0.32 7.18e-10 Longevity; LIHC trans rs2727020 0.595 rs11040416 chr11:49566429 C/T cg18944383 chr4:111397179 ENPEP 0.26 6.42 0.33 4.44e-10 Coronary artery disease; LIHC cis rs655641 0.954 rs3016327 chr11:85780448 T/C cg09030501 chr11:85779252 PICALM -0.51 -6.01 -0.31 4.83e-9 Platelet count; LIHC cis rs1577917 0.958 rs12199832 chr6:86652748 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.93 -0.35 2.09e-11 Response to antipsychotic treatment; LIHC cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs12477438 1.000 rs57846982 chr2:99921574 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.77 -8.9 -0.43 3.4e-17 Chronic sinus infection; LIHC cis rs13064411 0.627 rs9825827 chr3:113182231 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.28 -0.32 1.03e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs769267 0.965 rs1469712 chr19:19528821 C/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.87 0.3 1.03e-8 Tonsillectomy; LIHC cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg04267008 chr7:1944627 MAD1L1 -0.68 -10.85 -0.51 8.78e-24 Bipolar disorder and schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07120806 chr4:1873451 WHSC1 -0.5 -6.4 -0.33 5.12e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2070488 0.761 rs6807940 chr3:38460062 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.37 0.56 2.73e-29 Electrocardiographic conduction measures; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12112058 chr1:224622605 WDR26 0.49 7.2 0.36 3.93e-12 Pancreatic cancer; LIHC cis rs9952991 0.883 rs2542147 chr18:12775851 G/T cg23598886 chr18:12777645 NA 0.47 6.44 0.33 4.01e-10 Inflammatory skin disease; LIHC cis rs17095355 1.000 rs12570820 chr10:111732507 G/A cg00817464 chr10:111662876 XPNPEP1 -0.39 -5.82 -0.3 1.34e-8 Biliary atresia; LIHC cis rs2839186 0.632 rs17176110 chr21:47706535 C/A cg09417038 chr21:47716443 C21orf57 -0.58 -8.82 -0.43 5.79e-17 Testicular germ cell tumor; LIHC cis rs9583531 0.657 rs7318291 chr13:111352460 C/T cg15841412 chr13:111365552 ING1 -0.52 -6.36 -0.33 6.45e-10 Coronary artery disease; LIHC cis rs1008375 0.897 rs6820164 chr4:17630115 G/A cg02297831 chr4:17616191 MED28 0.43 6.16 0.32 2.03e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg25894440 chr7:65020034 NA 0.54 6.22 0.32 1.43e-9 Diabetic kidney disease; LIHC trans rs1814175 0.817 rs7946556 chr11:49944874 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC trans rs4714291 0.925 rs847755 chr6:40030378 T/C cg02267698 chr19:7991119 CTXN1 0.39 6.21 0.32 1.51e-9 Strep throat; LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.53 -7.52 -0.38 4.74e-13 Lymphocyte counts; LIHC cis rs2191566 0.747 rs4803667 chr19:44533604 T/C cg20607764 chr19:44506953 ZNF230 -0.42 -6.81 -0.35 4.48e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs8060686 0.641 rs113258243 chr16:68086656 C/T cg05110241 chr16:68378359 PRMT7 -0.6 -6.87 -0.35 2.96e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs9303401 0.614 rs35057477 chr17:57097064 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.26 0.55 7.01e-29 Cognitive test performance; LIHC trans rs7246657 0.943 rs7252325 chr19:37930645 A/G cg10208301 chr11:6592745 DNHD1 0.45 6.58 0.34 1.74e-10 Coronary artery calcification; LIHC cis rs4713118 0.869 rs9283881 chr6:27715255 A/T cg20933634 chr6:27740509 NA 0.47 6.19 0.32 1.69e-9 Parkinson's disease; LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg10360139 chr7:1886902 MAD1L1 -0.39 -6.01 -0.31 4.8e-9 Bipolar disorder and schizophrenia; LIHC cis rs5770917 1.000 rs762677 chr22:51017713 G/A cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.52 -7.0 -0.35 1.35e-11 Narcolepsy; LIHC cis rs8180040 0.966 rs56351005 chr3:47430186 G/T cg16586182 chr3:47516702 SCAP 0.6 11.82 0.54 2.88e-27 Colorectal cancer; LIHC trans rs4718428 0.705 rs12698547 chr7:66278258 T/C cg10756647 chr7:56101905 PSPH 0.63 8.64 0.42 2.14e-16 Corneal structure; LIHC cis rs7552404 0.727 rs4949677 chr1:76266662 T/A cg10523679 chr1:76189770 ACADM 0.57 7.03 0.36 1.11e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1670533 1.000 rs10031302 chr4:1059664 G/A cg27284194 chr4:1044797 NA 0.59 8.8 0.43 6.78e-17 Recombination rate (females); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg07474076 chr16:2972993 FLYWCH1 0.59 7.39 0.37 1.17e-12 Hepatitis; LIHC cis rs8078723 1.000 rs6503530 chr17:38161823 T/C cg17467752 chr17:38218738 THRA 0.76 13.99 0.6 1.82e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg09904177 chr6:26538194 HMGN4 0.56 10.95 0.51 3.94e-24 Intelligence (multi-trait analysis); LIHC cis rs752010 0.714 rs2182606 chr1:42082375 T/C cg06885757 chr1:42089581 HIVEP3 0.31 6.39 0.33 5.4e-10 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs9914988 0.832 rs9903248 chr17:27127439 G/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs4843747 0.671 rs4072871 chr16:88106614 C/T cg06050784 chr16:88016603 BANP 0.37 6.65 0.34 1.17e-10 Menopause (age at onset); LIHC cis rs6446731 0.517 rs2071671 chr4:3269787 C/G cg06533319 chr4:3265114 C4orf44 0.31 5.8 0.3 1.49e-8 Mean platelet volume; LIHC cis rs7927592 0.956 rs7106259 chr11:68298512 T/G cg01657329 chr11:68192670 LRP5 -0.46 -6.06 -0.31 3.61e-9 Total body bone mineral density; LIHC cis rs2204008 0.743 rs2127952 chr12:37995364 G/T cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs12701220 0.901 rs12701713 chr7:1090505 G/A cg16145915 chr7:1198662 ZFAND2A -0.31 -6.25 -0.32 1.23e-9 Bronchopulmonary dysplasia; LIHC cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg13047869 chr3:10149882 C3orf24 0.55 6.93 0.35 2.08e-11 Alzheimer's disease; LIHC cis rs4453791 1.000 rs4453791 chr3:38882519 T/C cg02254461 chr3:39195904 CSRNP1 0.66 5.88 0.3 9.58e-9 Social communication problems; LIHC cis rs6840360 1.000 rs7663045 chr4:152676350 T/C cg22705602 chr4:152727874 NA -0.34 -7.12 -0.36 6.24e-12 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02179239 chr10:23002514 PIP4K2A 0.38 6.13 0.31 2.42e-9 Cognitive function; LIHC cis rs8180040 0.615 rs13062681 chr3:47021124 A/G cg02527881 chr3:46936655 PTH1R -0.36 -7.16 -0.36 4.98e-12 Colorectal cancer; LIHC cis rs1348850 0.914 rs7591807 chr2:178252986 A/G cg27490568 chr2:178487706 NA 0.38 6.05 0.31 3.87e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9783347 1.000 rs4150575 chr11:18356466 C/T cg15585147 chr11:18324498 HPS5 0.42 6.7 0.34 8.6e-11 Pancreatic cancer; LIHC cis rs11583043 0.918 rs17525451 chr1:101422409 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.2 0.41 4.77e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7772486 0.875 rs9322046 chr6:146393625 A/G cg23711669 chr6:146136114 FBXO30 0.58 10.15 0.48 2.51e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs9814567 0.762 rs13075332 chr3:134329836 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.56 6.94 0.35 1.93e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1707322 1.000 rs785468 chr1:46521517 G/A cg03146154 chr1:46216737 IPP -0.44 -7.16 -0.36 4.84e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC cis rs11792861 0.926 rs72607163 chr9:111803128 G/T cg05043794 chr9:111880884 C9orf5 -0.3 -6.95 -0.35 1.87e-11 Menarche (age at onset); LIHC cis rs2842992 0.872 rs2758330 chr6:160104844 G/T cg16489826 chr6:160211363 TCP1;MRPL18 0.51 8.68 0.42 1.68e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg13395646 chr4:1353034 KIAA1530 -0.42 -5.97 -0.31 5.96e-9 Longevity; LIHC cis rs1046896 0.731 rs9906115 chr17:80791469 G/A cg02711726 chr17:80685570 FN3KRP -0.46 -8.32 -0.41 2.07e-15 Glycated hemoglobin levels; LIHC trans rs7246657 0.941 rs67293224 chr19:37803248 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.08 0.31 3.28e-9 Coronary artery calcification; LIHC cis rs4819052 0.684 rs914216 chr21:46698298 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 11.77 0.54 4.45e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9649465 1.000 rs13224762 chr7:123370710 A/G cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.25e-15 Migraine; LIHC cis rs3806843 1.000 rs1030165 chr5:140185448 G/A cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs1997066 0.920 rs7090127 chr10:106730305 C/G cg21239439 chr6:170038665 WDR27 0.67 6.08 0.31 3.23e-9 Diabetic kidney disease; LIHC cis rs919433 0.619 rs699318 chr2:198281743 T/C cg10820045 chr2:198174542 NA 0.54 8.75 0.43 1.01e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6831352 0.918 rs17218162 chr4:100056060 G/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg27170947 chr2:26402098 FAM59B 0.67 8.44 0.42 9.3e-16 Gut microbiome composition (summer); LIHC cis rs1712517 0.836 rs11191649 chr10:105067037 T/C cg05636881 chr10:105038444 INA 0.44 6.9 0.35 2.61e-11 Migraine; LIHC cis rs2153535 0.580 rs1319169 chr6:8464456 G/A cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs1552244 0.554 rs3732965 chr3:10048760 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.69 0.38 1.55e-13 Alzheimer's disease; LIHC cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg03264133 chr6:25882463 NA -0.62 -7.95 -0.4 2.66e-14 Intelligence (multi-trait analysis); LIHC cis rs10847980 0.590 rs77970074 chr12:123292186 T/G cg25930673 chr12:123319894 HIP1R 1.09 11.71 0.53 7.46e-27 Adiponectin levels; LIHC cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg04727924 chr7:799746 HEATR2 0.41 6.17 0.32 1.94e-9 Perceived unattractiveness to mosquitoes; LIHC cis rs2540917 0.728 rs11125839 chr2:60627401 G/C cg00543073 chr2:60773386 BCL11A -0.33 -6.57 -0.33 1.87e-10 Mean corpuscular volume; LIHC cis rs986417 1.000 rs12147690 chr14:60924009 A/G cg27398547 chr14:60952738 C14orf39 0.81 9.56 0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC cis rs904251 0.797 rs1757177 chr6:37486370 C/T cg01843034 chr6:37503916 NA -0.49 -7.94 -0.39 2.97e-14 Cognitive performance; LIHC trans rs17685 0.725 rs7807647 chr7:75628669 G/A cg19862616 chr7:65841803 NCRNA00174 -0.89 -17.85 -0.69 7.8e-51 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08862778 chr1:11322643 MTOR 0.44 7.25 0.36 2.79e-12 Cognitive function; LIHC cis rs7582720 1.000 rs72934707 chr2:203707878 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.03 0.31 4.27e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6952808 0.929 rs4721217 chr7:1973579 C/T cg02951883 chr7:2050386 MAD1L1 -0.65 -10.07 -0.48 4.77e-21 Bipolar disorder and schizophrenia; LIHC cis rs11190604 1.000 rs10883501 chr10:102238326 A/G cg07080220 chr10:102295463 HIF1AN 0.5 7.06 0.36 9.17e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9649213 0.593 rs6963210 chr7:97944986 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.83 -0.3 1.28e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs9916302 0.680 rs2271308 chr17:37817482 T/C cg07936489 chr17:37558343 FBXL20 -0.52 -7.86 -0.39 4.92e-14 Glomerular filtration rate (creatinine); LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg14004847 chr7:1930337 MAD1L1 -0.48 -7.17 -0.36 4.74e-12 Bipolar disorder and schizophrenia; LIHC cis rs526631 0.564 rs10896051 chr11:65578759 C/T cg04055107 chr11:65626734 MUS81;CFL1 -0.46 -6.61 -0.34 1.5e-10 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs8081395 0.741 rs1292055 chr17:57959068 A/G cg13753209 chr17:57696993 CLTC 0.38 5.74 0.3 2.08e-8 White blood cell count; LIHC cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.83 0.78 9.72e-71 Height; LIHC cis rs4853012 0.793 rs6723185 chr2:74344884 T/A cg20891558 chr2:74357851 NA 0.81 16.63 0.67 6.27e-46 Gestational age at birth (maternal effect); LIHC cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg06466757 chr4:1255808 NA 0.35 5.84 0.3 1.25e-8 Obesity-related traits; LIHC cis rs35110281 0.807 rs9976441 chr21:45046591 G/A cg01579765 chr21:45077557 HSF2BP -0.32 -6.13 -0.31 2.46e-9 Mean corpuscular volume; LIHC cis rs2991971 0.967 rs10789465 chr1:45971759 T/C cg05343316 chr1:45956843 TESK2 -0.42 -6.2 -0.32 1.62e-9 High light scatter reticulocyte count; LIHC cis rs713477 0.935 rs4901564 chr14:55912409 G/T cg13175173 chr14:55914753 NA -0.36 -8.26 -0.41 3.34e-15 Pediatric bone mineral content (femoral neck); LIHC trans rs2211698 1.000 rs59785817 chr21:35835645 C/T cg18044562 chr7:50468399 IKZF1 0.51 7.42 0.37 9.41e-13 Cancer; LIHC cis rs6918586 0.658 rs198822 chr6:26123539 G/C cg18357526 chr6:26021779 HIST1H4A -0.58 -8.85 -0.43 4.63e-17 Schizophrenia; LIHC cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg06656553 chr16:89960601 TCF25 -0.49 -6.22 -0.32 1.46e-9 Skin colour saturation; LIHC cis rs5769765 0.908 rs9627800 chr22:50319351 T/C cg09182678 chr22:50328711 NA -0.39 -5.82 -0.3 1.36e-8 Schizophrenia; LIHC cis rs7917772 0.629 rs1475646 chr10:104522564 G/T cg22532475 chr10:104410764 TRIM8 0.36 6.37 0.33 6.16e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs10761482 0.531 rs10740029 chr10:62238902 G/A cg17314160 chr12:110399253 GIT2 -0.41 -6.13 -0.31 2.37e-9 Schizophrenia; LIHC cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg12373951 chr3:133503437 NA 0.46 7.65 0.38 2.07e-13 Iron status biomarkers; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17707966 chr8:144718525 ZNF623 0.39 6.25 0.32 1.19e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2073499 0.935 rs2526395 chr3:50188886 T/C cg21659725 chr3:3221576 CRBN -0.65 -7.13 -0.36 5.94e-12 Schizophrenia; LIHC cis rs8072100 0.875 rs7208530 chr17:45544107 C/T cg08085267 chr17:45401833 C17orf57 -0.42 -6.17 -0.32 1.91e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg11890956 chr21:40555474 PSMG1 0.56 9.3 0.45 1.78e-18 Cognitive function; LIHC cis rs2204008 0.807 rs11182461 chr12:38539288 T/C cg13010199 chr12:38710504 ALG10B 0.55 6.54 0.33 2.27e-10 Bladder cancer; LIHC cis rs903552 0.736 rs9806495 chr15:102008059 G/A cg25677261 chr15:102009856 PCSK6 -0.53 -7.15 -0.36 5.45e-12 Diabetic kidney disease; LIHC cis rs9910055 0.530 rs2269907 chr17:42294215 G/A cg13607699 chr17:42295918 UBTF 0.66 11.68 0.53 9.17e-27 Total body bone mineral density; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg12923728 chr3:195709715 SDHAP1 0.6 6.92 0.35 2.22e-11 Lung disease severity in cystic fibrosis; LIHC cis rs526821 0.574 rs11230156 chr11:55334809 A/G cg04317927 chr11:55418816 OR4S2 0.47 8.99 0.44 1.66e-17 Pediatric bone mineral density (spine); LIHC cis rs5760092 0.572 rs738806 chr22:24234172 A/G cg11905131 chr22:24372483 LOC391322 -0.49 -5.85 -0.3 1.14e-8 Urinary 1,3-butadiene metabolite levels in smokers; LIHC cis rs6502050 0.835 rs12938965 chr17:80128646 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs9596863 0.898 rs17088922 chr13:54375033 T/C ch.13.53330881F chr13:54432880 NA 0.43 5.74 0.3 2.1e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs7659604 1.000 rs28433617 chr4:122664138 C/A cg19748678 chr4:122722346 EXOSC9 0.37 6.31 0.32 8.83e-10 Type 2 diabetes; LIHC cis rs7945718 0.875 rs9888258 chr11:12782716 A/G cg25843174 chr11:12811716 TEAD1 0.35 7.88 0.39 4.52e-14 Educational attainment (years of education); LIHC cis rs11608355 0.515 rs12579916 chr12:109924528 T/G cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs8056893 0.842 rs4783553 chr16:68365955 A/G cg02226672 chr16:68398533 SMPD3 -0.44 -6.01 -0.31 4.75e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25998860 chr5:126853954 PRRC1 0.51 7.3 0.37 2.09e-12 Pancreatic cancer; LIHC cis rs7945705 0.967 rs10769968 chr11:8907583 G/C cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.05 0.36 1e-11 Hemoglobin concentration; LIHC trans rs2727020 0.521 rs7107178 chr11:49526668 G/A cg15704280 chr7:45808275 SEPT13 0.8 11.97 0.54 8.05e-28 Coronary artery disease; LIHC cis rs644799 0.710 rs523153 chr11:95570961 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.73 12.19 0.55 1.23e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs916888 0.610 rs199529 chr17:44837217 A/C cg01570182 chr17:44337453 NA 0.91 9.23 0.45 2.82e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs875971 0.862 rs7782704 chr7:65805366 G/A cg18876405 chr7:65276391 NA -0.35 -6.36 -0.33 6.34e-10 Aortic root size; LIHC cis rs9916302 0.904 rs650106 chr17:37451559 A/G cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC cis rs17125944 0.505 rs74620173 chr14:53194068 G/T cg00686598 chr14:53173677 PSMC6 1.22 15.5 0.64 2.13e-41 Alzheimer's disease (late onset); LIHC cis rs763121 0.853 rs5757196 chr22:39039855 G/C cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs4638749 0.677 rs6711297 chr2:108818357 A/C cg06795125 chr2:108905320 SULT1C2 -0.29 -5.75 -0.3 1.94e-8 Blood pressure; LIHC cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.92 -10.43 -0.49 2.67e-22 Platelet count; LIHC cis rs881375 0.678 rs10760125 chr9:123662590 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.63 0.34 1.3e-10 Rheumatoid arthritis; LIHC cis rs7027203 0.828 rs10761288 chr9:96609363 C/T cg14396892 chr9:96623032 NA -0.32 -6.13 -0.31 2.37e-9 DNA methylation (variation); LIHC cis rs1577917 0.917 rs12202170 chr6:86590386 A/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.44 -7.17 -0.36 4.69e-12 Response to antipsychotic treatment; LIHC cis rs10254118 0.730 rs6961517 chr7:133130940 G/T cg10665199 chr7:133106180 EXOC4 0.48 7.77 0.39 9.41e-14 Intelligence (multi-trait analysis); LIHC cis rs2274273 0.901 rs112870553 chr14:55790062 T/G cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.37e-9 Protein biomarker; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.84 0.78 8.76e-71 Height; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg11905131 chr22:24372483 LOC391322 -0.61 -8.61 -0.42 2.71e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg11301795 chr4:187892539 NA -0.28 -7.44 -0.37 8.06e-13 Lobe attachment (rater-scored or self-reported); LIHC cis rs79149102 0.579 rs76900720 chr15:75348895 A/T cg09165964 chr15:75287851 SCAMP5 -0.61 -7.76 -0.39 1.02e-13 Lung cancer; LIHC cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.27 0.45 2.15e-18 Bipolar disorder; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07959124 chr10:75006630 DNAJC9 -0.44 -6.36 -0.33 6.58e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23029715 chr19:42363959 RPS19 0.37 6.46 0.33 3.71e-10 Pancreatic cancer; LIHC cis rs1371867 0.846 rs1616833 chr8:101271821 C/T cg06002616 chr8:101225028 SPAG1 0.36 6.25 0.32 1.24e-9 Atrioventricular conduction; LIHC cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg13126279 chr21:47581558 C21orf56 -0.39 -6.0 -0.31 5.06e-9 Testicular germ cell tumor; LIHC cis rs7224314 1.000 rs62084080 chr17:65387014 C/T cg01507342 chr17:65387096 PITPNC1 -0.49 -6.14 -0.32 2.23e-9 Diisocyanate-induced asthma; LIHC cis rs6701037 0.714 rs2285219 chr1:175130983 A/T cg00958927 chr1:175162553 KIAA0040 -0.39 -6.47 -0.33 3.46e-10 Alcohol dependence; LIHC cis rs7726839 0.561 rs72703046 chr5:580129 T/C cg09021430 chr5:549028 NA -0.41 -8.6 -0.42 2.95e-16 Obesity-related traits; LIHC cis rs8062405 0.824 rs4788083 chr16:28545449 A/G cg00204512 chr16:28754710 NA 0.33 6.74 0.34 6.69e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs244293 0.831 rs7207057 chr17:53172968 G/C cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.54 0.38 4.39e-13 Menarche (age at onset); LIHC cis rs992157 0.835 rs2292550 chr2:219140288 G/C cg00012203 chr2:219082015 ARPC2 -0.83 -13.05 -0.58 7.16e-32 Colorectal cancer; LIHC cis rs208520 0.690 rs1776365 chr6:66834474 G/T cg07460842 chr6:66804631 NA -0.76 -8.35 -0.41 1.75e-15 Exhaled nitric oxide output; LIHC cis rs875971 0.660 rs10950044 chr7:66042976 A/G cg18876405 chr7:65276391 NA -0.45 -7.86 -0.39 4.99e-14 Aortic root size; LIHC cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg13395646 chr4:1353034 KIAA1530 -0.63 -8.99 -0.44 1.66e-17 Obesity-related traits; LIHC cis rs11583043 0.918 rs11581062 chr1:101407519 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.73 -9.79 -0.47 4.12e-20 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2637266 0.935 rs2579728 chr10:78395598 A/G cg18941641 chr10:78392320 NA 0.29 6.4 0.33 5.23e-10 Pulmonary function; LIHC cis rs7617480 0.648 rs6801211 chr3:48774420 C/G cg07636037 chr3:49044803 WDR6 0.74 9.63 0.46 1.45e-19 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9916302 0.731 rs11868030 chr17:37650332 A/G cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC cis rs9322817 0.691 rs7743022 chr6:105170381 G/T cg02098413 chr6:105308735 HACE1 -0.42 -7.65 -0.38 2.02e-13 Thyroid stimulating hormone; LIHC cis rs9910055 0.530 rs2269906 chr17:42294337 G/T cg08499158 chr17:42289980 UBTF 0.46 7.42 0.37 9.19e-13 Total body bone mineral density; LIHC cis rs9814567 0.752 rs1534029 chr3:134330213 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6545883 0.831 rs1186704 chr2:61672991 A/G cg14146966 chr2:61757674 XPO1 0.45 7.76 0.39 9.9e-14 Tuberculosis; LIHC trans rs877282 1.000 rs12779159 chr10:772143 T/C cg22713356 chr15:30763199 NA 1.42 12.94 0.57 1.91e-31 Uric acid levels; LIHC trans rs11098499 0.780 rs10013652 chr4:120292256 A/G cg25214090 chr10:38739885 LOC399744 0.48 7.72 0.39 1.28e-13 Corneal astigmatism; LIHC cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg18357526 chr6:26021779 HIST1H4A 0.6 8.44 0.42 8.94e-16 Blood metabolite levels; LIHC cis rs9467773 1.000 rs9467796 chr6:26568411 A/G cg09904177 chr6:26538194 HMGN4 0.66 13.75 0.6 1.5e-34 Intelligence (multi-trait analysis); LIHC cis rs916888 0.773 rs199533 chr17:44828931 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.71 6.73 0.34 7.1e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs12142240 0.698 rs67941619 chr1:46838219 A/G cg00530320 chr1:46809349 NSUN4 0.54 5.77 0.3 1.76e-8 Menopause (age at onset); LIHC trans rs1005277 0.579 rs1621040 chr10:38497232 T/C cg23533926 chr12:111358616 MYL2 -0.35 -6.79 -0.34 4.94e-11 Extrinsic epigenetic age acceleration; LIHC cis rs12477438 0.748 rs7558239 chr2:99640581 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.84 -0.65 9.44e-43 Chronic sinus infection; LIHC cis rs6430585 0.583 rs58116536 chr2:136585323 C/T cg15123519 chr2:136567270 LCT -0.38 -5.82 -0.3 1.37e-8 Corneal structure; LIHC trans rs7618501 0.699 rs11130224 chr3:49936910 T/A cg21665057 chr3:196295764 WDR53;FBXO45 0.59 9.29 0.45 1.84e-18 Intelligence (multi-trait analysis); LIHC cis rs2836950 0.545 rs1888489 chr21:40533164 T/C cg11890956 chr21:40555474 PSMG1 -0.47 -7.78 -0.39 8.41e-14 Menarche (age at onset); LIHC cis rs2273669 0.667 rs12210444 chr6:109305743 T/C cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs2832191 0.791 rs2832196 chr21:30497412 G/A cg24692254 chr21:30365293 RNF160 -0.59 -10.28 -0.49 8.89e-22 Dental caries; LIHC cis rs17776563 0.887 rs72763808 chr15:89132114 G/A cg05013243 chr15:89149849 MIR1179 0.41 6.79 0.34 4.9e-11 Thyroid hormone levels; LIHC cis rs34172651 0.517 rs2303084 chr16:24834581 G/C cg00152838 chr16:24741724 TNRC6A -0.5 -5.76 -0.3 1.85e-8 Intelligence (multi-trait analysis); LIHC cis rs3812111 0.641 rs1547030 chr6:116418158 G/A cg08036074 chr6:116424633 NT5DC1 0.65 11.3 0.52 2.17e-25 Age-related macular degeneration; LIHC trans rs9388451 0.839 rs9401845 chr6:126104118 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.51 -8.14 -0.4 7.19e-15 Brugada syndrome; LIHC cis rs7584330 0.554 rs13395743 chr2:238437554 C/T cg08992911 chr2:238395768 MLPH 0.51 5.98 0.31 5.5e-9 Prostate cancer; LIHC cis rs9790314 1.000 rs460508 chr3:161091089 C/G cg03342759 chr3:160939853 NMD3 0.67 8.15 0.4 6.83e-15 Morning vs. evening chronotype; LIHC cis rs523522 0.962 rs9040 chr12:120900274 C/T cg27279351 chr12:120934652 DYNLL1 0.65 11.44 0.53 7.08e-26 High light scatter reticulocyte count; LIHC cis rs34779708 0.931 rs72789687 chr10:35372489 G/A cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.46 6.46 0.33 3.69e-10 Mean platelet volume; LIHC cis rs4742903 0.935 rs10119876 chr9:106961080 T/G cg14250997 chr9:106856677 SMC2 0.35 5.87 0.3 1.02e-8 High-grade serous ovarian cancer;Breast cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17494855 chr1:43855675 C1orf84;MED8 -0.5 -6.12 -0.31 2.5e-9 Systolic blood pressure; LIHC trans rs2727020 0.664 rs4929893 chr11:49196332 C/T cg15704280 chr7:45808275 SEPT13 -0.88 -16.14 -0.66 5.93e-44 Coronary artery disease; LIHC cis rs2806561 0.929 rs2867315 chr1:23541286 C/T cg19743168 chr1:23544995 NA -0.39 -7.19 -0.36 4.19e-12 Height; LIHC cis rs1866706 0.896 rs1440277 chr11:12875089 C/T cg25843174 chr11:12811716 TEAD1 -0.28 -6.05 -0.31 3.74e-9 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.520 rs13012481 chr2:99754290 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.26 0.64 1.81e-40 Chronic sinus infection; LIHC cis rs1670533 1.000 rs6852558 chr4:1059944 C/T cg27284194 chr4:1044797 NA 0.59 8.79 0.43 7.18e-17 Recombination rate (females); LIHC cis rs9790314 0.521 rs60625846 chr3:161084525 G/T cg17135325 chr3:160939158 NMD3 0.42 6.09 0.31 3.07e-9 Morning vs. evening chronotype; LIHC cis rs6942756 0.876 rs6953598 chr7:129033741 A/G cg02491457 chr7:128862824 NA 0.59 9.2 0.45 3.69e-18 White matter hyperintensity burden; LIHC cis rs700651 0.789 rs10497812 chr2:198911245 A/G cg10820045 chr2:198174542 NA -0.44 -6.42 -0.33 4.6e-10 Intracranial aneurysm; LIHC cis rs67460515 0.563 rs11720263 chr3:160848293 T/C cg17135325 chr3:160939158 NMD3 0.55 7.84 0.39 5.79e-14 Parkinson's disease; LIHC cis rs9682041 1.000 rs57508070 chr3:170074374 C/A cg11886554 chr3:170076028 SKIL 0.74 6.16 0.32 2.03e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs9549367 0.713 rs11620600 chr13:113829090 G/A cg00898013 chr13:113819073 PROZ -0.44 -7.39 -0.37 1.17e-12 Platelet distribution width; LIHC cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.78 14.93 0.63 3.82e-39 Menarche (age at onset); LIHC cis rs367615 0.552 rs2416210 chr5:108741137 C/T cg17395555 chr5:108820864 NA -0.28 -6.02 -0.31 4.41e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs7312774 0.618 rs12316476 chr12:107343326 C/G cg16260113 chr12:107380972 MTERFD3 0.85 11.16 0.52 7.43e-25 Severe influenza A (H1N1) infection; LIHC cis rs929354 0.707 rs1182445 chr7:157024428 C/G cg05182265 chr7:156933206 UBE3C 0.33 6.25 0.32 1.21e-9 Body mass index; LIHC cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg13877915 chr19:58951672 ZNF132 0.64 10.93 0.51 4.58e-24 Uric acid clearance; LIHC cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.3 0.37 2.02e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6089584 0.821 rs2273990 chr20:60579149 G/T cg12751644 chr20:60527061 NA -0.37 -6.1 -0.31 2.93e-9 Body mass index; LIHC cis rs7772486 0.790 rs9403755 chr6:146231470 C/A cg05347473 chr6:146136440 FBXO30 -0.36 -5.93 -0.31 7.24e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7551222 0.752 rs10793766 chr1:204549496 C/T cg20240347 chr1:204465584 NA -0.35 -6.97 -0.35 1.66e-11 Schizophrenia; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg11494091 chr17:61959527 GH2 0.43 7.76 0.39 1.01e-13 Prudent dietary pattern; LIHC trans rs9929218 0.954 rs35444713 chr16:68824492 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.37 -0.41 1.53e-15 Colorectal cancer; LIHC cis rs1865760 0.892 rs9379806 chr6:25940958 G/A cg15691649 chr6:25882328 NA -0.39 -6.15 -0.32 2.17e-9 Height; LIHC cis rs7662987 0.517 rs2602872 chr4:100038996 A/G cg12011299 chr4:100065546 ADH4 0.66 10.86 0.51 8.12e-24 Smoking initiation; LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg11965913 chr1:205819406 PM20D1 0.7 9.82 0.47 3.29e-20 Menarche (age at onset); LIHC cis rs611744 0.647 rs1457211 chr8:109261318 C/T cg18478394 chr8:109455254 TTC35 -0.43 -7.31 -0.37 1.86e-12 Dupuytren's disease; LIHC cis rs4820539 1.000 rs916583 chr22:23469267 C/T cg21100191 chr22:23484243 RTDR1 0.91 16.61 0.67 7.94e-46 Bone mineral density; LIHC trans rs1814175 0.645 rs11040671 chr11:49958776 G/A cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs12893668 0.572 rs1606 chr14:104161281 G/A cg24130564 chr14:104152367 KLC1 -0.55 -9.57 -0.46 2.3e-19 Reticulocyte count; LIHC cis rs4555082 0.834 rs2816624 chr14:105733909 A/G cg10792982 chr14:105748885 BRF1 0.46 6.08 0.31 3.14e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.14 0.36 5.5e-12 Renal cell carcinoma; LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 25.4 0.81 1.03e-80 Prudent dietary pattern; LIHC cis rs12188164 0.561 rs2721010 chr5:456915 A/G cg24955955 chr5:415729 AHRR 0.32 6.5 0.33 2.79e-10 Cystic fibrosis severity; LIHC cis rs9381040 0.672 rs6458197 chr6:41144658 C/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.43 -6.8 -0.35 4.62e-11 Alzheimer's disease (late onset); LIHC cis rs796364 0.806 rs11688194 chr2:200916239 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC cis rs9534288 0.619 rs2146881 chr13:46679598 T/C cg15192986 chr13:46630673 CPB2 -0.43 -5.92 -0.3 8.02e-9 Blood protein levels; LIHC cis rs7772486 0.558 rs702322 chr6:146007166 G/A cg05347473 chr6:146136440 FBXO30 -0.44 -6.65 -0.34 1.17e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs801193 1.000 rs13239306 chr7:66136017 T/G cg26939375 chr7:64535504 NA -0.43 -7.0 -0.35 1.39e-11 Aortic root size; LIHC trans rs2359714 0.905 rs56366235 chr1:118830161 A/G cg19861078 chr7:7936962 NA 0.32 6.09 0.31 2.97e-9 Breast size; LIHC cis rs9612 0.950 rs346546 chr19:44256910 T/C cg08581076 chr19:44259116 C19orf61 0.69 8.98 0.44 1.8e-17 Exhaled nitric oxide output; LIHC cis rs10464366 0.571 rs13233049 chr7:39187536 C/T cg20302533 chr7:39170763 POU6F2 0.38 7.02 0.35 1.22e-11 IgG glycosylation; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.59 9.0 0.44 1.57e-17 Height; LIHC cis rs7503807 0.967 rs12949279 chr17:78558411 T/C cg09596252 chr17:78655493 RPTOR 0.37 6.55 0.33 2.17e-10 Obesity; LIHC cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs5758511 0.633 rs5751258 chr22:42663871 C/G cg00645731 chr22:42541494 CYP2D7P1 0.52 8.29 0.41 2.59e-15 Birth weight; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg06989074 chr11:68133177 LRP5 0.4 6.53 0.33 2.4e-10 Bilirubin levels; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg21548813 chr6:291882 DUSP22 -0.6 -8.55 -0.42 4.1e-16 Menopause (age at onset); LIHC cis rs916888 0.773 rs199535 chr17:44822662 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.73 6.85 0.35 3.46e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs55665837 0.523 rs10832301 chr11:14788964 G/A cg00085434 chr11:14927489 NA 0.4 5.77 0.3 1.78e-8 Vitamin D levels; LIHC cis rs7772486 0.754 rs2328709 chr6:146106819 A/G cg13319975 chr6:146136371 FBXO30 0.41 6.75 0.34 6.54e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16048161 chr11:31391307 DNAJC24;DCDC1 -0.47 -6.57 -0.33 1.85e-10 Pancreatic cancer; LIHC trans rs116095464 0.619 rs2303741 chr5:218356 T/C cg00938859 chr5:1591904 SDHAP3 0.56 6.61 0.34 1.5e-10 Breast cancer; LIHC cis rs6840360 1.000 rs9995704 chr4:152619069 C/A cg22705602 chr4:152727874 NA -0.32 -6.82 -0.35 4.27e-11 Intelligence (multi-trait analysis); LIHC trans rs7395662 0.591 rs11039858 chr11:48611651 C/T cg15704280 chr7:45808275 SEPT13 -0.46 -6.79 -0.34 5.04e-11 HDL cholesterol; LIHC cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs3806843 0.518 rs2569191 chr5:140013903 C/T cg19875535 chr5:140030758 IK -0.35 -5.86 -0.3 1.07e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs3008870 0.959 rs56707923 chr1:67388016 T/C cg02640540 chr1:67518911 SLC35D1 0.42 5.78 0.3 1.64e-8 Lymphocyte percentage of white cells; LIHC trans rs60843830 1.000 rs56321614 chr2:268191 G/T cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.47 0.46 4.87e-19 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs67460515 0.563 rs11922957 chr3:160828865 A/C cg17135325 chr3:160939158 NMD3 0.55 7.82 0.39 6.82e-14 Parkinson's disease; LIHC trans rs7613875 0.600 rs2856237 chr3:50158774 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.41 -6.28 -0.32 1.01e-9 Body mass index; LIHC cis rs477692 0.673 rs579325 chr10:131363688 C/T cg05714579 chr10:131428358 MGMT 0.44 6.98 0.35 1.54e-11 Response to temozolomide; LIHC cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs2274273 0.870 rs10149420 chr14:55854257 T/C cg04306507 chr14:55594613 LGALS3 0.33 6.05 0.31 3.77e-9 Protein biomarker; LIHC cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg07424592 chr7:64974309 NA -0.46 -6.9 -0.35 2.59e-11 Calcium levels; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.93 0.57 2.1e-31 Prudent dietary pattern; LIHC cis rs11864453 0.560 rs6499561 chr16:72148404 A/G cg01557791 chr16:72042693 DHODH -0.48 -7.91 -0.39 3.59e-14 Fibrinogen levels; LIHC cis rs1395 0.778 rs6749393 chr2:27451000 C/T cg23587288 chr2:27483067 SLC30A3 -0.33 -6.07 -0.31 3.45e-9 Blood metabolite levels; LIHC cis rs11711311 0.911 rs3773681 chr3:113523901 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.01 0.44 1.5e-17 IgG glycosylation; LIHC cis rs7520050 0.966 rs7556615 chr1:46461369 G/A cg03146154 chr1:46216737 IPP -0.38 -6.27 -0.32 1.11e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2932538 0.922 rs6537745 chr1:113154080 T/C cg22162597 chr1:113214053 CAPZA1 0.68 10.71 0.5 2.84e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg14709524 chr16:89940631 TCF25 0.51 6.44 0.33 4.1e-10 Skin colour saturation; LIHC cis rs7777484 0.534 rs2258709 chr7:2832365 C/T cg18446336 chr7:2847575 GNA12 0.31 6.16 0.32 2.04e-9 Height; LIHC cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg26338869 chr17:61819248 STRADA 0.59 8.35 0.41 1.73e-15 Prudent dietary pattern; LIHC cis rs12477438 0.748 rs6712773 chr2:99585781 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.6 -0.5 6.66e-23 Chronic sinus infection; LIHC cis rs903552 0.736 rs9806369 chr15:102008430 A/C cg25677261 chr15:102009856 PCSK6 -0.53 -7.22 -0.36 3.47e-12 Diabetic kidney disease; LIHC cis rs2230307 0.536 rs629340 chr1:100538621 A/T cg24955406 chr1:100503596 HIAT1 0.6 5.99 0.31 5.44e-9 Carotid intima media thickness; LIHC cis rs2806561 1.000 rs1757048 chr1:23510601 A/C cg19743168 chr1:23544995 NA 0.42 8.04 0.4 1.52e-14 Height; LIHC cis rs9399135 0.967 rs9402676 chr6:135355507 C/T cg24558204 chr6:135376177 HBS1L 0.43 7.05 0.36 9.7e-12 Red blood cell count; LIHC cis rs7589728 0.563 rs4972044 chr2:88466196 T/C cg07952391 chr2:88470173 THNSL2 0.8 7.6 0.38 2.86e-13 Plasma clusterin levels; LIHC cis rs6977660 0.619 rs10263780 chr7:19778086 A/G cg07541023 chr7:19748670 TWISTNB -0.5 -7.41 -0.37 9.98e-13 Thyroid stimulating hormone; LIHC cis rs11122272 0.735 rs2808600 chr1:231534723 T/C cg06096015 chr1:231504339 EGLN1 0.51 9.42 0.45 6.73e-19 Hemoglobin concentration; LIHC cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg02290350 chr8:58132656 NA 0.41 8.51 0.42 5.58e-16 Developmental language disorder (linguistic errors); LIHC cis rs6963495 0.538 rs55967123 chr7:105163678 C/A cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg11301795 chr4:187892539 NA -0.26 -6.89 -0.35 2.62e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1580019 0.547 rs56981934 chr7:32535202 C/G cg06627557 chr7:32535165 LSM5;AVL9 1.15 26.7 0.82 1.2e-85 Cognitive ability; LIHC cis rs875971 0.825 rs6951503 chr7:65718936 T/G cg11764359 chr7:65958608 NA -0.79 -13.81 -0.6 8.55e-35 Aortic root size; LIHC cis rs2050392 0.894 rs303430 chr10:30706235 C/A cg25182066 chr10:30743637 MAP3K8 -0.47 -7.62 -0.38 2.52e-13 Inflammatory bowel disease; LIHC cis rs2404602 1.000 rs1117367 chr15:76872330 A/C cg23625390 chr15:77176239 SCAPER 0.38 6.36 0.33 6.31e-10 Blood metabolite levels; LIHC cis rs1949733 0.701 rs940136 chr4:8448992 G/A cg11789530 chr4:8429930 ACOX3 0.76 11.06 0.51 1.59e-24 Response to antineoplastic agents; LIHC cis rs2243480 0.706 rs34466769 chr7:65453292 A/C cg05590025 chr7:65112418 INTS4L2 -0.49 -5.92 -0.3 7.8e-9 Diabetic kidney disease; LIHC cis rs10540 0.915 rs12419209 chr11:494510 T/C cg03352830 chr11:487213 PTDSS2 0.82 6.88 0.35 2.9e-11 Body mass index; LIHC cis rs9858542 0.953 rs9824092 chr3:49674147 C/G cg03060546 chr3:49711283 APEH -0.6 -7.97 -0.4 2.35e-14 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs12477438 0.748 rs4851185 chr2:99666497 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs6545883 0.929 rs1186700 chr2:61663372 A/C cg15711740 chr2:61764176 XPO1 -0.43 -6.05 -0.31 3.81e-9 Tuberculosis; LIHC trans rs916888 0.779 rs430685 chr17:44859148 T/C cg07870213 chr5:140052090 DND1 -1.0 -10.32 -0.49 6.22e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs951366 0.789 rs823121 chr1:205724302 A/G cg14159672 chr1:205819179 PM20D1 -0.71 -9.98 -0.47 9.37e-21 Menarche (age at onset); LIHC cis rs7927771 0.864 rs3781626 chr11:47442893 A/T cg20307385 chr11:47447363 PSMC3 -0.48 -6.33 -0.32 7.73e-10 Subjective well-being; LIHC cis rs875971 0.862 rs11765791 chr7:65936574 A/G cg18252515 chr7:66147081 NA -0.44 -6.3 -0.32 9.07e-10 Aortic root size; LIHC cis rs903552 0.673 rs4965878 chr15:102009589 C/T cg25677261 chr15:102009856 PCSK6 -0.52 -6.93 -0.35 2.11e-11 Diabetic kidney disease; LIHC trans rs911555 0.755 rs2756132 chr14:103967820 C/G cg17675199 chr6:35436792 RPL10A -0.45 -9.35 -0.45 1.21e-18 Intelligence (multi-trait analysis); LIHC cis rs72627123 0.867 rs117818304 chr14:74474396 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.88 9.06 0.44 1.01e-17 Morning vs. evening chronotype; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg01516881 chr6:292596 DUSP22 -0.51 -6.65 -0.34 1.15e-10 Menopause (age at onset); LIHC cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg04083430 chr16:4736063 MGRN1 -0.42 -5.84 -0.3 1.24e-8 Schizophrenia; LIHC cis rs7582180 0.568 rs10186134 chr2:100939501 T/A cg14675211 chr2:100938903 LONRF2 0.54 8.06 0.4 1.28e-14 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.57 -8.21 -0.41 4.51e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg11644478 chr21:40555479 PSMG1 -0.38 -6.04 -0.31 3.95e-9 Menarche (age at onset); LIHC cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg17971929 chr21:40555470 PSMG1 0.81 9.65 0.46 1.24e-19 Cognitive function; LIHC cis rs929354 0.772 rs6459737 chr7:156975136 G/A cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs9457247 0.534 rs9355610 chr6:167383075 G/A cg23791538 chr6:167370224 RNASET2 0.75 14.28 0.61 1.27e-36 Crohn's disease; LIHC cis rs986417 0.901 rs10150982 chr14:60987006 T/G cg27398547 chr14:60952738 C14orf39 0.75 8.1 0.4 9.98e-15 Gut microbiota (bacterial taxa); LIHC cis rs6831352 0.703 rs2602854 chr4:100028651 C/T cg12011299 chr4:100065546 ADH4 0.56 9.87 0.47 2.2e-20 Alcohol dependence; LIHC trans rs4843747 0.605 rs4072779 chr16:88107290 C/T cg26811252 chr16:29126840 RRN3P2 0.41 6.61 0.34 1.46e-10 Menopause (age at onset); LIHC cis rs600806 0.778 rs2152924 chr1:110011701 G/A cg10127483 chr1:110009974 SYPL2 0.5 6.37 0.33 6.23e-10 Intelligence (multi-trait analysis); LIHC cis rs2120019 0.567 rs68036747 chr15:75203200 A/C cg09165964 chr15:75287851 SCAMP5 -0.49 -6.52 -0.33 2.54e-10 Blood trace element (Zn levels); LIHC cis rs3008870 0.755 rs4655662 chr1:67416432 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.78 0.5 1.59e-23 Lymphocyte percentage of white cells; LIHC cis rs10847980 0.590 rs1979236 chr12:123325993 G/A cg22842854 chr12:123319900 HIP1R 0.83 9.26 0.45 2.24e-18 Adiponectin levels; LIHC cis rs1707322 0.752 rs11211147 chr1:46110094 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.52 0.38 4.74e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg11764359 chr7:65958608 NA 0.59 6.21 0.32 1.5e-9 Diabetic kidney disease; LIHC cis rs972578 0.967 rs4822235 chr22:43338090 T/C cg01576275 chr22:43409880 NA -0.33 -5.91 -0.3 8.33e-9 Mean platelet volume; LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs7927771 0.826 rs2293578 chr11:47437403 C/T cg20307385 chr11:47447363 PSMC3 -0.46 -5.97 -0.31 5.98e-9 Subjective well-being; LIHC cis rs875971 1.000 rs3735148 chr7:65971009 T/G cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.61e-9 Aortic root size; LIHC cis rs6466055 0.669 rs7797912 chr7:104769415 C/T cg04380332 chr7:105027541 SRPK2 0.35 6.72 0.34 7.72e-11 Schizophrenia; LIHC cis rs8180040 0.654 rs13078131 chr3:47204939 G/T cg27129171 chr3:47204927 SETD2 0.7 12.56 0.56 5.11e-30 Colorectal cancer; LIHC cis rs2032447 0.839 rs6901039 chr6:26000885 A/C cg12310025 chr6:25882481 NA -0.56 -7.13 -0.36 6.1e-12 Intelligence (multi-trait analysis); LIHC cis rs1034435 0.755 rs5768679 chr22:48892847 T/G cg05992904 chr22:48892994 FAM19A5 -0.53 -10.87 -0.51 7.81e-24 Late-onset Alzheimer's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08575122 chr10:33269417 NA 0.56 7.29 0.37 2.17e-12 Lung function (FEV1/FVC); LIHC cis rs9303280 0.901 rs9901146 chr17:38043343 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.81 0.3 1.45e-8 Self-reported allergy; LIHC cis rs2228479 0.702 rs62053702 chr16:89860688 G/T cg04013166 chr16:89971882 TCF25 0.49 5.91 0.3 8.48e-9 Skin colour saturation; LIHC cis rs7100689 0.646 rs1934696 chr10:82124966 T/C cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs8016982 0.630 rs61980900 chr14:81686436 T/C cg01989461 chr14:81687754 GTF2A1 0.7 14.59 0.62 8.35e-38 Schizophrenia; LIHC cis rs11673344 0.598 rs826326 chr19:37494765 T/C cg27390819 chr19:37464633 NA -0.48 -6.27 -0.32 1.06e-9 Obesity-related traits; LIHC cis rs10744422 0.748 rs2292138 chr12:123339712 A/G cg25930673 chr12:123319894 HIP1R -0.96 -12.76 -0.57 9.14e-31 Schizophrenia; LIHC cis rs7098414 0.511 rs7916349 chr10:82152638 G/A cg00277334 chr10:82204260 NA -0.61 -10.07 -0.48 4.66e-21 Post bronchodilator FEV1; LIHC cis rs5769707 0.632 rs1476037 chr22:49991377 G/A cg07959070 chr22:50026188 C22orf34 -0.32 -8.07 -0.4 1.24e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg13152130 chr6:118910203 C6orf204 -0.65 -7.34 -0.37 1.61e-12 Diastolic blood pressure; LIHC cis rs875971 0.545 rs801212 chr7:66015630 C/G cg11764359 chr7:65958608 NA -0.61 -8.83 -0.43 5.48e-17 Aortic root size; LIHC cis rs1568889 0.838 rs11030185 chr11:28041904 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 13.94 0.6 2.66e-35 Bipolar disorder; LIHC cis rs9309473 0.632 rs6546825 chr2:73592253 G/C cg20560298 chr2:73613845 ALMS1 -0.44 -6.92 -0.35 2.2e-11 Metabolite levels; LIHC cis rs644799 0.544 rs1254935 chr11:95631470 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.57 8.09 0.4 1.08e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg12463550 chr7:65579703 CRCP -0.66 -6.84 -0.35 3.6e-11 Diabetic kidney disease; LIHC cis rs2576037 0.526 rs642897 chr18:44396917 T/G cg19077165 chr18:44547161 KATNAL2 -0.43 -6.55 -0.33 2.16e-10 Personality dimensions; LIHC cis rs2404602 0.692 rs12594556 chr15:77165363 G/A cg23625390 chr15:77176239 SCAPER 0.35 5.74 0.3 2.04e-8 Blood metabolite levels; LIHC cis rs1055129 0.560 rs2305913 chr17:73922941 T/C cg08125733 chr17:73851984 WBP2 0.57 8.73 0.43 1.16e-16 White matter hyperintensity burden; LIHC cis rs769267 0.930 rs4808208 chr19:19650096 A/G cg03709012 chr19:19516395 GATAD2A 1.01 17.07 0.68 1.1e-47 Tonsillectomy; LIHC cis rs4727027 0.866 rs7778766 chr7:148806729 A/G cg23583168 chr7:148888333 NA -0.68 -9.58 -0.46 2.05e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs9457247 0.555 rs2247325 chr6:167369992 A/G cg23791538 chr6:167370224 RNASET2 0.69 11.04 0.51 1.91e-24 Crohn's disease; LIHC cis rs546131 0.614 rs473885 chr11:34851961 G/A cg11058730 chr11:34937778 PDHX;APIP 0.64 9.38 0.45 9.45e-19 Lung disease severity in cystic fibrosis; LIHC trans rs1814175 0.645 rs28441045 chr11:50048971 C/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs3806843 1.000 rs1548700 chr5:140164889 A/T cg26395211 chr5:140044315 WDR55 -0.41 -6.12 -0.31 2.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs12477438 0.501 rs13008171 chr2:99743419 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs1062177 1.000 rs2347596 chr5:151179199 T/C cg00977110 chr5:151150581 G3BP1 0.55 6.98 0.35 1.56e-11 Preschool internalizing problems; LIHC cis rs7618501 0.602 rs2240326 chr3:50128386 G/A cg24110177 chr3:50126178 RBM5 0.54 8.71 0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs116248771 0.793 rs12494750 chr3:158298411 T/G cg16708174 chr3:158430962 RARRES1 0.47 6.21 0.32 1.54e-9 diarrhoeal disease at age 2; LIHC cis rs3806843 0.966 rs6891559 chr5:140145206 G/A cg19875535 chr5:140030758 IK 0.38 6.23 0.32 1.39e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs1814175 0.817 rs10769618 chr11:49822336 A/G cg15704280 chr7:45808275 SEPT13 -1.02 -23.26 -0.78 1.91e-72 Height; LIHC cis rs2635047 0.935 rs2461247 chr18:44698537 T/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.45 6.0 0.31 5.09e-9 Educational attainment; LIHC trans rs61931739 0.500 rs7307583 chr12:34521711 T/C cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs10870270 0.956 rs7904594 chr10:133734671 C/T cg26149184 chr10:133730230 NA 0.46 7.34 0.37 1.56e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs3768617 0.510 rs3768624 chr1:183079252 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.66 0.5 4.09e-23 Fuchs's corneal dystrophy; LIHC cis rs9359856 0.529 rs56352205 chr6:90439272 C/T cg13799429 chr6:90582589 CASP8AP2 -0.64 -5.95 -0.31 6.49e-9 Bipolar disorder; LIHC cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg11766577 chr21:47581405 C21orf56 -0.38 -5.87 -0.3 1.01e-8 Testicular germ cell tumor; LIHC cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs7116495 1.000 rs1573502 chr11:71747428 C/T cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs769267 0.965 rs2315281 chr19:19480099 G/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.01 -0.31 4.78e-9 Tonsillectomy; LIHC cis rs9611519 0.929 rs73174660 chr22:41437304 T/C cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.13e-14 Neuroticism; LIHC cis rs7131987 0.622 rs7294598 chr12:29531989 A/C cg21486233 chr12:29375141 FAR2 -0.29 -5.72 -0.3 2.36e-8 QT interval; LIHC trans rs10213084 1.000 rs10212994 chr4:147501225 A/G cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs2073300 0.609 rs6137914 chr20:23358364 C/T cg12062639 chr20:23401060 NAPB 1.08 14.27 0.61 1.47e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04180668 chr6:163148903 PARK2;PACRG 0.48 6.44 0.33 3.96e-10 Pancreatic cancer; LIHC cis rs7666738 0.830 rs28618180 chr4:98912184 A/C cg05340658 chr4:99064831 C4orf37 0.64 11.65 0.53 1.25e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs74233809 1.000 rs11191453 chr10:104659852 T/C cg03493300 chr10:104813866 CNNM2 0.44 5.89 0.3 9.48e-9 Birth weight; LIHC cis rs3099143 1.000 rs35645941 chr15:77140302 C/T cg21673338 chr15:77095150 SCAPER -0.48 -7.41 -0.37 9.74e-13 Recalcitrant atopic dermatitis; LIHC cis rs6840360 0.571 rs11931934 chr4:152552082 A/G cg22705602 chr4:152727874 NA -0.32 -6.23 -0.32 1.4e-9 Intelligence (multi-trait analysis); LIHC cis rs2439831 1.000 rs2444029 chr15:43737484 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.67 0.59 3.13e-34 Lung cancer in ever smokers; LIHC cis rs7666738 0.830 rs6839203 chr4:98839814 C/G cg05340658 chr4:99064831 C4orf37 0.63 11.57 0.53 2.45e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs3015497 0.587 rs1353204 chr14:51081515 C/T cg09863266 chr14:51125203 SAV1 -0.36 -5.78 -0.3 1.71e-8 Mean platelet volume; LIHC cis rs12644436 0.628 rs4693187 chr4:88783355 A/T cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs7772486 0.754 rs697053 chr6:145989807 T/C cg23711669 chr6:146136114 FBXO30 -0.74 -13.45 -0.59 2.24e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs10089 0.953 rs114881127 chr5:127369661 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.74 0.34 6.7e-11 Ileal carcinoids; LIHC cis rs515186 1 rs515186 chr6:36397492 T/G cg07856975 chr6:36356162 ETV7 0.36 5.87 0.3 1.02e-8 Mean platelet volume; LIHC cis rs7605378 0.567 rs717915 chr2:200714766 C/T cg23649088 chr2:200775458 C2orf69 0.62 8.79 0.43 7.51e-17 Osteoporosis; LIHC cis rs7772486 0.790 rs4075694 chr6:146251108 G/C cg13319975 chr6:146136371 FBXO30 0.38 6.04 0.31 3.92e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7703051 0.585 rs918623 chr5:74596682 A/C cg07671805 chr5:74907694 NA 0.46 6.29 0.32 9.84e-10 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs919433 0.589 rs7601800 chr2:198395099 T/C cg03934865 chr2:198174659 NA 0.51 7.74 0.39 1.13e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs7980799 0.618 rs1482983 chr12:33690326 A/C cg26384229 chr12:38710491 ALG10B 0.45 6.06 0.31 3.56e-9 Heart rate;Heart rate variability traits (RMSSD); LIHC cis rs6504950 0.745 rs9914088 chr17:52979985 T/C cg10237252 chr17:52977213 TOM1L1 -0.38 -6.58 -0.34 1.77e-10 Breast cancer; LIHC cis rs311392 0.554 rs311386 chr8:55101507 A/G cg20636351 chr8:55087400 NA -0.34 -7.09 -0.36 7.97e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs11105298 0.838 rs4842488 chr12:89881564 C/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.55 -0.38 3.92e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10870270 1.000 rs4880250 chr10:133773919 G/A cg08754478 chr10:133766260 PPP2R2D -0.55 -8.05 -0.4 1.39e-14 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs1865760 0.892 rs6456705 chr6:25936056 G/A cg15691649 chr6:25882328 NA -0.39 -6.15 -0.32 2.11e-9 Height; LIHC cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg09177884 chr7:1199841 ZFAND2A -0.49 -7.28 -0.37 2.37e-12 Longevity;Endometriosis; LIHC cis rs7534824 0.556 rs61780323 chr1:101433407 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.69 6.96 0.35 1.75e-11 Refractive astigmatism; LIHC trans rs1814175 0.591 rs11040589 chr11:49862449 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.43e-11 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02046995 chr22:41487740 EP300;MIR1281 0.44 6.43 0.33 4.27e-10 Lung function (FEV1/FVC); LIHC cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg11663144 chr21:46675770 NA 0.34 6.32 0.32 8.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs36051895 0.623 rs11790680 chr9:5248768 C/T cg02405213 chr9:5042618 JAK2 -0.63 -9.95 -0.47 1.17e-20 Pediatric autoimmune diseases; LIHC cis rs9467773 0.967 rs6932865 chr6:26540166 C/A cg09904177 chr6:26538194 HMGN4 0.66 13.73 0.6 1.84e-34 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.559 rs242281 chr6:88048916 A/C cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.32 0.37 1.74e-12 Monocyte percentage of white cells; LIHC cis rs2274273 0.686 rs28631821 chr14:55845987 T/C cg04306507 chr14:55594613 LGALS3 0.32 5.99 0.31 5.4e-9 Protein biomarker; LIHC cis rs523522 0.962 rs603574 chr12:120998443 A/G cg12219531 chr12:120966889 COQ5 0.68 13.54 0.59 9.99e-34 High light scatter reticulocyte count; LIHC cis rs6952808 0.609 rs4721190 chr7:1954732 A/G cg14004847 chr7:1930337 MAD1L1 0.54 7.88 0.39 4.36e-14 Bipolar disorder and schizophrenia; LIHC cis rs6815814 0.950 rs5743563 chr4:38806019 A/G cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC cis rs8072100 0.967 rs7221548 chr17:45582952 T/C cg08085267 chr17:45401833 C17orf57 0.38 5.78 0.3 1.69e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs17102423 0.594 rs1957948 chr14:65542629 A/G cg16583315 chr14:65563665 MAX 0.38 7.75 0.39 1.07e-13 Obesity-related traits; LIHC cis rs898097 0.812 rs72859941 chr17:80837459 G/A cg15664640 chr17:80829946 TBCD -0.78 -12.87 -0.57 3.49e-31 Breast cancer; LIHC cis rs2404602 0.716 rs12592171 chr15:76755133 G/C cg03037974 chr15:76606532 NA 0.8 16.45 0.66 3.41e-45 Blood metabolite levels; LIHC cis rs1005277 0.505 rs7069702 chr10:38247359 G/T cg25427524 chr10:38739819 LOC399744 0.65 12.71 0.57 1.41e-30 Extrinsic epigenetic age acceleration; LIHC cis rs5769765 0.908 rs7410318 chr22:50317049 T/C cg02269571 chr22:50332266 NA -0.66 -8.93 -0.43 2.74e-17 Schizophrenia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26126750 chr3:195809198 TFRC -0.44 -6.1 -0.31 2.87e-9 Systolic blood pressure; LIHC cis rs2251381 0.778 rs2471947 chr21:30534219 G/T cg24692254 chr21:30365293 RNF160 0.71 10.23 0.48 1.32e-21 Selective IgA deficiency; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg24685795 chr17:34851276 ZNHIT3 -0.39 -6.64 -0.34 1.26e-10 Calcium levels; LIHC cis rs875971 1.000 rs4717300 chr7:65947380 T/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC trans rs1814175 0.588 rs10466497 chr11:49864381 A/T cg18944383 chr4:111397179 ENPEP 0.27 6.99 0.35 1.41e-11 Height; LIHC cis rs4474465 0.607 rs7930161 chr11:78268878 C/A cg02023728 chr11:77925099 USP35 -0.35 -6.21 -0.32 1.56e-9 Alzheimer's disease (survival time); LIHC cis rs12744310 0.887 rs4453028 chr1:41792523 G/A cg03962019 chr1:41807865 NA 0.38 6.13 0.31 2.47e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs6500602 0.787 rs7204624 chr16:4459834 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.46 6.55 0.33 2.16e-10 Schizophrenia; LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg20570016 chr1:156261298 TMEM79 0.36 5.79 0.3 1.58e-8 Tonsillectomy; LIHC cis rs4953076 0.573 rs7602070 chr2:44388614 G/A cg04920474 chr2:44395004 PPM1B 0.51 5.98 0.31 5.64e-9 Height; LIHC cis rs10751667 0.600 rs4076915 chr11:1012464 C/G cg06064525 chr11:970664 AP2A2 -0.44 -10.73 -0.5 2.49e-23 Alzheimer's disease (late onset); LIHC cis rs9768139 0.708 rs921616 chr7:158117960 A/G cg25566285 chr7:158114605 PTPRN2 0.22 5.97 0.31 6.03e-9 Calcium levels; LIHC cis rs644799 0.504 rs523049 chr11:95594831 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.65 10.47 0.49 1.95e-22 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3781458 0.803 rs11245321 chr10:126323279 C/T cg20435097 chr10:126320824 FAM53B 0.7 13.09 0.58 5.04e-32 Male-pattern baldness; LIHC cis rs9534288 0.702 rs7331472 chr13:46644173 C/T cg15192986 chr13:46630673 CPB2 -0.44 -6.68 -0.34 9.87e-11 Blood protein levels; LIHC cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg26939375 chr7:64535504 NA 0.47 8.25 0.41 3.36e-15 Calcium levels; LIHC cis rs4919087 0.962 rs3740522 chr10:99019144 C/T cg25902810 chr10:99078978 FRAT1 0.65 9.59 0.46 1.84e-19 Monocyte count; LIHC cis rs11663156 0.774 rs117467762 chr18:50933942 C/A cg24270629 chr18:50823537 DCC -0.49 -6.7 -0.34 8.66e-11 Intelligence (multi-trait analysis); LIHC cis rs4665809 1.000 rs1030730 chr2:26284143 T/C cg27170947 chr2:26402098 FAM59B -0.68 -8.34 -0.41 1.88e-15 Gut microbiome composition (summer); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25631650 chr19:633157 POLRMT 0.45 6.21 0.32 1.52e-9 Pancreatic cancer; LIHC cis rs9522267 0.737 rs12429582 chr13:112226657 A/G cg10483660 chr13:112241077 NA -0.23 -5.9 -0.3 8.65e-9 Hepatitis; LIHC cis rs2153535 0.580 rs1034273 chr6:8468145 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg22528358 chr1:107598549 PRMT6 0.72 11.83 0.54 2.66e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4589502 0.800 rs4147433 chr15:67201152 G/A cg12317470 chr15:67143691 NA -0.53 -6.74 -0.34 6.9e-11 Lung cancer (smoking interaction); LIHC cis rs79976124 0.797 rs74995761 chr6:66640216 G/A cg07460842 chr6:66804631 NA 0.66 7.02 0.35 1.22e-11 Type 2 diabetes; LIHC cis rs332507 0.830 rs2289428 chr3:124412524 T/G cg05980111 chr3:124395277 KALRN 0.44 6.78 0.34 5.21e-11 Plateletcrit; LIHC cis rs35110281 0.837 rs2838336 chr21:45071741 A/G cg01579765 chr21:45077557 HSF2BP 0.31 6.11 0.31 2.67e-9 Mean corpuscular volume; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg07810114 chr1:12018622 PLOD1 0.46 6.83 0.35 3.86e-11 Bilirubin levels; LIHC cis rs6708331 0.517 rs12999042 chr2:70366811 C/T cg01613454 chr2:70366299 NA 0.38 6.23 0.32 1.39e-9 Obesity-related traits; LIHC cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC trans rs877282 0.853 rs10904545 chr10:757100 G/A cg22713356 chr15:30763199 NA 1.36 11.96 0.54 8.66e-28 Uric acid levels; LIHC cis rs12368653 0.666 rs799267 chr12:58113158 C/T cg12615879 chr12:58013172 SLC26A10 0.34 6.77 0.34 5.45e-11 Multiple sclerosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg08393024 chr5:115177154 ATG12;AP3S1 0.45 6.22 0.32 1.46e-9 Lung function (FEV1/FVC); LIHC cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.92e-16 Prudent dietary pattern; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg13525026 chr17:18061071 MYO15A 0.41 6.43 0.33 4.23e-10 Immature fraction of reticulocytes; LIHC cis rs79149102 0.579 rs74023935 chr15:75359184 T/C cg15902774 chr15:75289873 SCAMP5 0.44 6.49 0.33 3.08e-10 Lung cancer; LIHC cis rs17253792 0.822 rs80328469 chr14:56067701 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.66 -0.34 1.1e-10 Putamen volume; LIHC cis rs11674184 0.714 rs16857668 chr2:11723110 G/A cg07314298 chr2:11723111 GREB1 -0.66 -12.87 -0.57 3.46e-31 Endometriosis; LIHC cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg06481639 chr22:41940642 POLR3H -0.64 -6.63 -0.34 1.29e-10 Vitiligo; LIHC cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg02475777 chr4:1388615 CRIPAK 0.53 7.9 0.39 3.77e-14 Longevity; LIHC trans rs9388451 1.000 rs9388451 chr6:126090377 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.57 -8.98 -0.44 1.82e-17 Brugada syndrome; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11635401 chr19:17322527 MYO9B 0.48 6.05 0.31 3.82e-9 Systolic blood pressure; LIHC cis rs10464366 0.571 rs13233049 chr7:39187536 C/T cg18850127 chr7:39170497 POU6F2 0.45 8.07 0.4 1.2e-14 IgG glycosylation; LIHC cis rs780096 0.526 rs11682621 chr2:27749669 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.14 -0.32 2.29e-9 Total body bone mineral density; LIHC cis rs7552404 0.690 rs11161620 chr1:76255228 A/G cg10523679 chr1:76189770 ACADM -0.59 -7.58 -0.38 3.35e-13 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs600806 0.821 rs417270 chr1:109849144 T/C cg02415029 chr1:110025642 ATXN7L2 -0.49 -6.03 -0.31 4.24e-9 Intelligence (multi-trait analysis); LIHC cis rs921968 0.565 rs6436084 chr2:219639782 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2832191 1.000 rs6516891 chr21:30483070 C/T cg08807101 chr21:30365312 RNF160 -0.6 -9.38 -0.45 9.5e-19 Dental caries; LIHC cis rs7172677 0.768 rs72730586 chr15:75354165 G/A cg09165964 chr15:75287851 SCAMP5 0.5 7.22 0.36 3.33e-12 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9814567 0.806 rs1880375 chr3:134322163 C/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6840360 0.533 rs11099829 chr4:152727299 A/G cg22705602 chr4:152727874 NA 0.37 7.79 0.39 8e-14 Intelligence (multi-trait analysis); LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg02594498 chr15:22893147 CYFIP1 -0.4 -6.13 -0.31 2.48e-9 Body mass index; LIHC cis rs2834188 0.883 rs16997869 chr21:34696867 C/T cg14352951 chr21:34696688 IFNAR1 -0.48 -6.6 -0.34 1.59e-10 Narcolepsy; LIHC cis rs1555322 0.530 rs2425043 chr20:33868702 T/C cg08210727 chr20:33865349 NA 0.5 5.88 0.3 9.93e-9 Attention deficit hyperactivity disorder; LIHC trans rs7618501 0.570 rs7613875 chr3:49971514 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.55 8.71 0.43 1.36e-16 Intelligence (multi-trait analysis); LIHC cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg14004847 chr7:1930337 MAD1L1 -0.42 -6.08 -0.31 3.13e-9 Bipolar disorder and schizophrenia; LIHC cis rs12928939 0.723 rs71403864 chr16:71695030 C/T cg03805757 chr16:71968109 PKD1L3 -0.64 -7.18 -0.36 4.46e-12 Post bronchodilator FEV1; LIHC cis rs6951245 0.935 rs11766669 chr7:1063593 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.74 -6.02 -0.31 4.58e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05628496 chr17:17991167 DRG2 0.44 6.09 0.31 2.96e-9 Pancreatic cancer; LIHC cis rs1538970 0.962 rs7532762 chr1:45864695 C/A cg15605315 chr1:45957053 TESK2 -0.42 -5.74 -0.3 2.12e-8 Platelet count; LIHC cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg16049864 chr8:95962084 TP53INP1 -0.62 -12.06 -0.55 3.69e-28 Type 2 diabetes; LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg09177884 chr7:1199841 ZFAND2A -0.43 -5.9 -0.3 8.51e-9 Longevity;Endometriosis; LIHC cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg05368731 chr17:41323189 NBR1 0.73 12.56 0.56 5.23e-30 Menopause (age at onset); LIHC trans rs7618501 0.933 rs1128535 chr3:49866392 C/T cg19936157 chr1:113287238 NA -0.33 -6.03 -0.31 4.15e-9 Intelligence (multi-trait analysis); LIHC cis rs6912958 0.559 rs446851 chr6:88043640 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.38 0.37 1.2e-12 Monocyte percentage of white cells; LIHC cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.81 7.93 0.39 3.19e-14 Platelet count; LIHC cis rs7131987 0.650 rs10843382 chr12:29451721 G/A cg21522988 chr12:29376872 FAR2 0.26 5.83 0.3 1.29e-8 QT interval; LIHC cis rs3820500 0.543 rs1289951 chr1:117913019 A/G cg20383390 chr1:117909022 MAN1A2 -0.45 -5.74 -0.3 2.11e-8 Pneumonia; LIHC trans rs2832191 0.716 rs1543652 chr21:30448000 G/C cg14791747 chr16:20752902 THUMPD1 -0.47 -6.53 -0.33 2.42e-10 Dental caries; LIHC trans rs867371 0.762 rs1846910 chr15:82571780 G/A cg18393722 chr15:85113863 UBE2QP1 -0.44 -7.43 -0.37 8.55e-13 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.08 11.64 0.53 1.34e-26 Platelet count; LIHC cis rs754466 0.651 rs11818687 chr10:79637709 C/T cg17075019 chr10:79541650 NA -0.75 -11.39 -0.52 1.11e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3768617 0.624 rs34105373 chr1:183098387 T/C ch.1.3577855R chr1:183094577 LAMC1 0.48 7.68 0.38 1.65e-13 Fuchs's corneal dystrophy; LIHC cis rs2576037 0.796 rs2571032 chr18:44578250 T/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.21 -0.36 3.52e-12 Personality dimensions; LIHC cis rs7165170 0.529 rs4932357 chr15:91160884 C/A cg26821196 chr15:91095069 CRTC3 0.32 5.91 0.3 8.47e-9 Crohn's disease;Inflammatory bowel disease; LIHC cis rs748404 0.697 rs1814323 chr15:43563237 T/C cg02155558 chr15:43621948 ADAL;LCMT2 -0.44 -6.78 -0.34 5.41e-11 Lung cancer; LIHC cis rs4843747 0.605 rs28399183 chr16:88107277 G/A cg06050784 chr16:88016603 BANP 0.36 6.57 0.33 1.93e-10 Menopause (age at onset); LIHC cis rs2404602 0.647 rs7178250 chr15:77099107 T/C cg03037974 chr15:76606532 NA -0.61 -10.35 -0.49 5.08e-22 Blood metabolite levels; LIHC cis rs4409675 0.576 rs10751724 chr1:28215631 C/T cg23691781 chr1:28212827 C1orf38 0.32 7.66 0.38 1.96e-13 Corneal astigmatism; LIHC cis rs7833986 0.534 rs17814089 chr8:56965563 A/G cg23139584 chr8:56987506 RPS20;SNORD54 -0.87 -9.18 -0.44 4.33e-18 Height; LIHC cis rs9660992 0.710 rs1668873 chr1:205235990 G/A cg21545522 chr1:205238299 TMCC2 0.4 7.87 0.39 4.88e-14 Mean corpuscular volume;Mean platelet volume; LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg07677032 chr17:61819896 STRADA 0.44 6.42 0.33 4.45e-10 Prudent dietary pattern; LIHC cis rs10089 1.000 rs4836370 chr5:127499224 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.43 0.33 4.37e-10 Ileal carcinoids; LIHC cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg25897951 chr4:1244024 CTBP1;C4orf42 -0.42 -6.05 -0.31 3.91e-9 Longevity; LIHC trans rs12753920 0.703 rs1601020 chr1:92621428 G/T cg15668468 chr10:118892869 VAX1 0.42 6.12 0.31 2.58e-9 Systemic lupus erythematosus; LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg02290350 chr8:58132656 NA 0.49 8.85 0.43 4.69e-17 Developmental language disorder (linguistic errors); LIHC cis rs655641 1.000 rs616555 chr11:85710180 G/A cg09030501 chr11:85779252 PICALM -0.53 -6.19 -0.32 1.69e-9 Platelet count; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg14651457 chr8:12611650 LONRF1 0.69 6.12 0.31 2.6e-9 Musician's dystonia; LIHC cis rs4642101 0.640 rs12629398 chr3:12826799 A/G cg24848339 chr3:12840334 CAND2 0.33 6.82 0.35 4.12e-11 QRS complex (12-leadsum); LIHC trans rs11098499 0.863 rs11933966 chr4:120476715 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.47 0.46 4.64e-19 Corneal astigmatism; LIHC cis rs7635838 0.892 rs9310381 chr3:11458466 A/G cg00170343 chr3:11313890 ATG7 0.43 6.7 0.34 8.45e-11 HDL cholesterol; LIHC cis rs17125944 0.505 rs10483617 chr14:53202605 A/G cg00686598 chr14:53173677 PSMC6 -1.31 -15.55 -0.64 1.33e-41 Alzheimer's disease (late onset); LIHC cis rs12142240 0.731 rs6658556 chr1:46844180 A/C cg14993813 chr1:46806288 NSUN4 -0.66 -5.8 -0.3 1.55e-8 Menopause (age at onset); LIHC cis rs10752881 0.901 rs10911201 chr1:183001622 G/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.27 0.49 9.23e-22 Colorectal cancer; LIHC cis rs7589728 1.000 rs12473740 chr2:88527647 A/G cg04511125 chr2:88470314 THNSL2 0.74 6.86 0.35 3.26e-11 Plasma clusterin levels; LIHC cis rs9916302 0.851 rs11078906 chr17:37662767 C/T cg00129232 chr17:37814104 STARD3 -0.42 -6.81 -0.35 4.45e-11 Glomerular filtration rate (creatinine); LIHC cis rs6951245 0.542 rs28460147 chr7:1217192 G/A cg18402987 chr7:1209562 NA 0.86 6.08 0.31 3.3e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6088590 1.000 rs2295353 chr20:33356511 C/T cg24642439 chr20:33292090 TP53INP2 0.78 10.69 0.5 3.41e-23 Coronary artery disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg26207102 chr11:12748969 TEAD1 -0.25 -6.04 -0.31 3.99e-9 Calcium levels; LIHC cis rs9549367 0.789 rs6577031 chr13:113878182 T/C cg18105134 chr13:113819100 PROZ 0.56 10.03 0.48 6.2e-21 Platelet distribution width; LIHC cis rs7208859 0.573 rs8078656 chr17:29080971 A/T cg14067834 chr17:29058358 SUZ12P 0.69 6.82 0.35 4.22e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6545883 0.868 rs2441381 chr2:61798829 C/T cg14146966 chr2:61757674 XPO1 0.48 8.37 0.41 1.5e-15 Tuberculosis; LIHC cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg09904177 chr6:26538194 HMGN4 0.57 11.56 0.53 2.66e-26 Intelligence (multi-trait analysis); LIHC cis rs1046896 0.514 rs67735447 chr17:80823042 G/T cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.35 0.32 6.87e-10 Glycated hemoglobin levels; LIHC cis rs1348850 0.958 rs12471741 chr2:178448196 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.75 11.22 0.52 4.41e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs875971 0.660 rs7807930 chr7:66087165 C/T cg14393609 chr7:65229607 NA -0.38 -6.03 -0.31 4.36e-9 Aortic root size; LIHC cis rs801193 1.000 rs6975195 chr7:66124774 T/A cg11764359 chr7:65958608 NA -0.71 -10.58 -0.5 8.16e-23 Aortic root size; LIHC trans rs7939886 0.920 rs1552151 chr11:55780951 A/G cg15704280 chr7:45808275 SEPT13 -0.61 -6.07 -0.31 3.47e-9 Myopia (pathological); LIHC cis rs6964587 0.967 rs12535601 chr7:91718346 A/G cg17063962 chr7:91808500 NA 1.01 19.29 0.72 1.22e-56 Breast cancer; LIHC cis rs2066819 1.000 rs116535779 chr12:56739261 A/G cg26734620 chr12:56694298 CS 0.99 10.18 0.48 2.03e-21 Psoriasis vulgaris; LIHC cis rs10870270 0.917 rs11146417 chr10:133791034 C/G cg08754478 chr10:133766260 PPP2R2D -0.54 -7.65 -0.38 2.04e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs11190604 1.000 rs4917901 chr10:102201773 A/C cg07080220 chr10:102295463 HIF1AN 0.48 6.82 0.35 4.11e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6952809 0.532 rs7803015 chr7:2432143 G/A cg23289794 chr7:2394357 EIF3B -0.61 -6.28 -0.32 1e-9 Multiple sclerosis; LIHC cis rs4853012 0.838 rs59570457 chr2:74344282 T/C cg05890377 chr2:74357713 NA 0.63 12.81 0.57 5.75e-31 Gestational age at birth (maternal effect); LIHC cis rs12477438 0.748 rs7558239 chr2:99640581 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -10.77 -0.5 1.69e-23 Chronic sinus infection; LIHC cis rs425277 0.606 rs262653 chr1:2090095 T/G cg24578937 chr1:2090814 PRKCZ 0.33 6.11 0.31 2.75e-9 Height; LIHC cis rs6088590 0.710 rs6059992 chr20:33282275 T/C cg24642439 chr20:33292090 TP53INP2 0.47 6.51 0.33 2.72e-10 Coronary artery disease; LIHC cis rs9486719 0.656 rs6924957 chr6:96853579 G/T cg06623918 chr6:96969491 KIAA0776 0.49 6.38 0.33 5.65e-10 Migraine;Coronary artery disease; LIHC trans rs6489882 0.703 rs2660 chr12:113357442 A/G cg10175203 chr3:128143634 NA -0.39 -6.21 -0.32 1.55e-9 Chronic lymphocytic leukemia; LIHC cis rs12477438 0.798 rs6705583 chr2:99602625 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.15 -17.08 -0.68 9.71e-48 Chronic sinus infection; LIHC cis rs17384381 0.953 rs11161597 chr1:85784936 G/A cg16011679 chr1:85725395 C1orf52 0.84 9.1 0.44 7.8e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs2842992 0.747 rs9365095 chr6:160192928 T/G cg16489826 chr6:160211363 TCP1;MRPL18 0.5 8.78 0.43 8.08e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs2163237 0.965 rs6748103 chr2:55986042 C/T cg03859395 chr2:55845619 SMEK2 0.45 6.86 0.35 3.3e-11 IgG glycosylation; LIHC cis rs2153535 0.580 rs9505454 chr6:8478532 T/G cg23788917 chr6:8435910 SLC35B3 0.58 8.3 0.41 2.41e-15 Motion sickness; LIHC cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg02869306 chr7:64672164 INTS4L1 -0.31 -6.61 -0.34 1.5e-10 Calcium levels; LIHC cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg09222892 chr1:25734099 RHCE -0.44 -8.09 -0.4 1.03e-14 Erythrocyte sedimentation rate; LIHC cis rs10872587 0.657 rs11155459 chr6:146578751 A/G cg23711669 chr6:146136114 FBXO30 -0.42 -6.24 -0.32 1.31e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg09455208 chr3:40491958 NA 0.42 8.46 0.42 7.64e-16 Renal cell carcinoma; LIHC cis rs10128251 0.746 rs9424194 chr10:5724073 A/G cg24097872 chr10:5724021 NA 0.76 12.27 0.55 6.54e-29 Childhood ear infection; LIHC cis rs4803468 1.000 rs4803463 chr19:41911040 C/G cg14132834 chr19:41945861 ATP5SL -0.44 -6.48 -0.33 3.26e-10 Height; LIHC cis rs497273 0.530 rs2701185 chr12:121352974 A/G cg02403541 chr12:121454288 C12orf43 0.37 5.79 0.3 1.55e-8 Systemic lupus erythematosus; LIHC cis rs7223966 1.000 rs11079509 chr17:61762148 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 7.05 0.36 9.84e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2304069 0.913 rs7734382 chr5:149383241 A/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.98 12.81 0.57 6.07e-31 HIV-1 control; LIHC cis rs898097 0.812 rs8065641 chr17:80820259 A/G cg15369054 chr17:80825471 TBCD 0.46 6.53 0.33 2.45e-10 Breast cancer; LIHC cis rs4819052 0.851 rs2236445 chr21:46678453 T/C cg22633049 chr21:46681294 NA -0.37 -6.42 -0.33 4.48e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8062405 0.755 rs55792032 chr16:28599411 A/G cg16576597 chr16:28551801 NUPR1 0.47 7.33 0.37 1.69e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1865760 0.892 rs6456705 chr6:25936056 G/A cg17691542 chr6:26056736 HIST1H1C 0.4 6.0 0.31 4.97e-9 Height; LIHC cis rs11971779 0.941 rs7802779 chr7:139122579 G/T cg07862535 chr7:139043722 LUC7L2 0.61 9.25 0.45 2.57e-18 Diisocyanate-induced asthma; LIHC cis rs12824058 0.799 rs4759656 chr12:130815804 G/A cg26677194 chr12:130822605 PIWIL1 0.51 7.17 0.36 4.52e-12 Menopause (age at onset); LIHC cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg15691649 chr6:25882328 NA 0.48 6.5 0.33 2.79e-10 Intelligence (multi-trait analysis); LIHC cis rs988712 0.705 rs4923463 chr11:27672500 A/G cg18117895 chr11:27722066 BDNF 0.49 6.88 0.35 2.89e-11 Obesity; LIHC cis rs8017423 0.935 rs2236403 chr14:90736325 C/T cg14092571 chr14:90743983 NA 0.46 7.24 0.36 2.94e-12 Mortality in heart failure; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg13500206 chr10:81146051 ZCCHC24 0.45 6.43 0.33 4.18e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs7552404 1.000 rs4949876 chr1:76173377 C/T cg22875332 chr1:76189707 ACADM 0.49 7.19 0.36 4.19e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9902453 1.000 rs12600993 chr17:28291222 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 11.62 0.53 1.54e-26 Coffee consumption (cups per day); LIHC cis rs1865760 0.566 rs9379821 chr6:26054268 A/C cg18357526 chr6:26021779 HIST1H4A 0.46 6.76 0.34 5.79e-11 Height; LIHC cis rs5769707 0.967 rs9616713 chr22:50049109 G/A cg01652190 chr22:50026171 C22orf34 -0.31 -6.95 -0.35 1.83e-11 Monocyte count;Monocyte percentage of white cells; LIHC trans rs9641123 0.639 rs7786765 chr7:93199928 T/A cg09745688 chr16:2908918 PRSS22 -0.37 -6.34 -0.32 7.31e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09820084 chr6:18387507 RNF144B 0.44 7.34 0.37 1.61e-12 Cognitive function; LIHC cis rs60871478 0.786 rs55899111 chr7:827843 C/G cg27478167 chr7:817139 HEATR2 0.52 6.96 0.35 1.77e-11 Cerebrospinal P-tau181p levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15319206 chr6:159065938 DYNLT1 -0.43 -6.9 -0.35 2.61e-11 Calcium levels; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.733 rs4391768 chr10:35547595 A/G cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13668652 chr20:33680648 TRPC4AP -0.54 -6.2 -0.32 1.59e-9 Systolic blood pressure; LIHC cis rs3818285 0.959 rs35420248 chr10:111643074 C/T cg00817464 chr10:111662876 XPNPEP1 -0.41 -6.05 -0.31 3.77e-9 Superior crus of antihelix expression; LIHC cis rs11675119 0.501 rs9309716 chr2:3493355 A/G cg15506890 chr2:3487001 NA -0.41 -6.15 -0.32 2.16e-9 Neurofibrillary tangles; LIHC cis rs965469 0.842 rs6051776 chr20:3332062 T/C cg25506879 chr20:3388711 C20orf194 -0.58 -6.97 -0.35 1.63e-11 IFN-related cytopenia; LIHC cis rs2842992 0.709 rs1853257 chr6:160212710 C/G cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.88 0.57 3.26e-31 Age-related macular degeneration (geographic atrophy); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03513682 chr16:85542749 NA -0.44 -6.49 -0.33 3.04e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs1355223 0.844 rs12809046 chr11:34748261 T/A cg11058730 chr11:34937778 PDHX;APIP -0.48 -6.52 -0.33 2.5e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7980687 0.628 rs1727332 chr12:123718301 C/T cg05973401 chr12:123451056 ABCB9 0.44 6.14 0.32 2.3e-9 Height;Educational attainment;Head circumference (infant); LIHC cis rs763121 0.925 rs9611008 chr22:39098787 T/C cg21395723 chr22:39101663 GTPBP1 0.36 6.03 0.31 4.32e-9 Menopause (age at onset); LIHC cis rs999943 0.846 rs2274200 chr6:33625696 T/C cg14003231 chr6:33640908 ITPR3 0.39 7.78 0.39 8.43e-14 Obesity (extreme); LIHC cis rs7927771 1.000 rs11605774 chr11:47832793 G/A cg20307385 chr11:47447363 PSMC3 -0.45 -5.81 -0.3 1.39e-8 Subjective well-being; LIHC cis rs7903847 0.642 rs11189179 chr10:99143320 T/C cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12908161 1.000 rs4643294 chr15:85250253 C/T cg12863693 chr15:85201151 NMB 0.48 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs7512552 0.839 rs698916 chr1:150388385 A/G cg15654264 chr1:150340011 RPRD2 0.68 11.1 0.51 1.2e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs6988636 1.000 rs13261100 chr8:124190312 G/A cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs1707322 1.000 rs4660334 chr1:46462126 A/C cg03146154 chr1:46216737 IPP 0.48 7.92 0.39 3.33e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7666738 0.546 rs11097591 chr4:98910173 G/A cg05340658 chr4:99064831 C4orf37 0.47 6.18 0.32 1.78e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2997447 0.637 rs3008413 chr1:26407063 G/A cg19633962 chr1:26362018 EXTL1 -0.6 -5.71 -0.3 2.43e-8 QRS complex (12-leadsum); LIHC cis rs769267 0.895 rs2965183 chr19:19545696 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.84 0.3 1.22e-8 Tonsillectomy; LIHC cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.31 -0.37 1.87e-12 Diabetic kidney disease; LIHC cis rs208520 0.874 rs208518 chr6:66948501 C/G cg07460842 chr6:66804631 NA 0.67 7.62 0.38 2.46e-13 Exhaled nitric oxide output; LIHC cis rs9914988 0.673 rs12325788 chr17:27080049 G/A cg20469991 chr17:27169893 C17orf63 -0.49 -6.04 -0.31 4.11e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs5753037 0.838 rs131293 chr22:30171031 T/G cg01021169 chr22:30184971 ASCC2 -0.35 -6.54 -0.33 2.25e-10 Type 1 diabetes; LIHC cis rs921968 0.584 rs2305833 chr2:219305404 G/C cg18887096 chr2:219472410 PLCD4 0.4 6.92 0.35 2.27e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs4566357 0.615 rs12328878 chr2:227918962 G/A cg16088116 chr21:44841560 SIK1 -0.42 -6.34 -0.32 7.23e-10 Coronary artery disease; LIHC cis rs10744422 0.800 rs2649902 chr12:123243687 G/A cg18912006 chr12:123335444 HIP1R -0.52 -6.13 -0.31 2.41e-9 Schizophrenia; LIHC cis rs9733 0.621 rs6669122 chr1:150591732 A/G cg13175981 chr1:150552382 MCL1 0.62 9.76 0.47 5.05e-20 Tonsillectomy; LIHC cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg10096929 chr1:156261403 TMEM79 0.38 6.38 0.33 5.69e-10 Tonsillectomy; LIHC cis rs7027203 0.797 rs7870672 chr9:96606693 A/C cg14396892 chr9:96623032 NA -0.33 -6.3 -0.32 9.26e-10 DNA methylation (variation); LIHC cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg10360139 chr7:1886902 MAD1L1 -0.38 -5.89 -0.3 9.28e-9 Bipolar disorder and schizophrenia; LIHC cis rs7618501 0.540 rs11130241 chr3:50131459 A/T cg24110177 chr3:50126178 RBM5 0.54 8.71 0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs2549003 0.870 rs61175929 chr5:131821548 C/G cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs875971 0.965 rs28682868 chr7:65689809 C/T cg18876405 chr7:65276391 NA -0.38 -6.88 -0.35 2.82e-11 Aortic root size; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.77 0.62 1.61e-38 Prudent dietary pattern; LIHC cis rs7523273 1.000 rs1142469 chr1:207965427 G/A cg22525895 chr1:207977042 MIR29B2 -0.68 -10.82 -0.5 1.19e-23 Schizophrenia; LIHC cis rs2073499 1.000 rs76846888 chr3:50406058 C/T cg03645007 chr3:50255295 SLC38A3 0.49 5.75 0.3 1.98e-8 Schizophrenia; LIHC trans rs526821 0.595 rs629948 chr11:55356448 G/A cg15704280 chr7:45808275 SEPT13 -0.52 -7.8 -0.39 7.35e-14 Pediatric bone mineral density (spine); LIHC cis rs7618501 0.602 rs2301166 chr3:50148305 C/G cg24110177 chr3:50126178 RBM5 0.53 8.66 0.42 1.91e-16 Intelligence (multi-trait analysis); LIHC cis rs992157 0.835 rs12987180 chr2:219144089 G/A cg00012203 chr2:219082015 ARPC2 -0.82 -13.08 -0.58 5.58e-32 Colorectal cancer; LIHC cis rs477895 0.713 rs35095324 chr11:63948412 G/A cg18225595 chr11:63971243 STIP1 0.69 8.46 0.42 7.65e-16 Mean platelet volume; LIHC cis rs1865760 0.516 rs9393683 chr6:26066198 A/G cg18357526 chr6:26021779 HIST1H4A 0.49 7.18 0.36 4.37e-12 Height; LIHC cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg01518246 chr11:63870912 FLRT1;MACROD1 0.45 6.39 0.33 5.55e-10 Attention deficit hyperactivity disorder; LIHC cis rs1008375 1.000 rs10805358 chr4:17652450 A/C cg16339924 chr4:17578868 LAP3 0.42 5.87 0.3 1.02e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7772486 0.782 rs7747576 chr6:146277827 C/T cg23711669 chr6:146136114 FBXO30 -0.63 -10.95 -0.51 3.96e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs6598955 0.670 rs12733645 chr1:26540356 G/T cg00852783 chr1:26633632 UBXN11 0.47 7.97 0.4 2.37e-14 Obesity-related traits; LIHC cis rs7181230 1.000 rs11638521 chr15:40360314 T/C cg00868766 chr15:40364524 NA -0.35 -5.75 -0.3 2e-8 Dehydroepiandrosterone sulphate levels; LIHC cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg06108461 chr20:60628389 TAF4 -1.02 -17.6 -0.69 7.98e-50 Body mass index; LIHC cis rs611744 0.506 rs4735054 chr8:109261780 A/C cg21045802 chr8:109455806 TTC35 -0.62 -11.24 -0.52 3.85e-25 Dupuytren's disease; LIHC cis rs3820068 0.581 rs78175477 chr1:15948091 C/G cg17385448 chr1:15911702 AGMAT 0.35 6.11 0.31 2.78e-9 Systolic blood pressure; LIHC trans rs10506458 1.000 rs12425932 chr12:63410497 C/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.72 -10.28 -0.49 8.79e-22 Hemostatic factors and hematological phenotypes; LIHC cis rs7715806 0.500 rs17563995 chr5:75007556 A/G cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11792861 0.926 rs3750451 chr9:111822866 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.84 0.43 5.31e-17 Menarche (age at onset); LIHC cis rs1434579 0.526 rs204547 chr19:44947184 T/C cg15540054 chr19:45004280 ZNF180 -0.48 -6.35 -0.32 6.85e-10 Tuberculosis; LIHC cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg20607798 chr8:58055168 NA 0.74 8.55 0.42 4.04e-16 Developmental language disorder (linguistic errors); LIHC trans rs62103177 0.564 rs55867755 chr18:77723434 C/T cg05926928 chr17:57297772 GDPD1 0.65 6.95 0.35 1.83e-11 Opioid sensitivity; LIHC cis rs2842992 0.915 rs1967802 chr6:160097791 G/A cg26839252 chr6:160211577 TCP1;MRPL18 0.37 6.12 0.31 2.62e-9 Age-related macular degeneration (geographic atrophy); LIHC cis rs6500602 0.701 rs8129 chr16:4562351 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.57 8.62 0.42 2.54e-16 Schizophrenia; LIHC cis rs6815814 0.799 rs11466640 chr4:38778903 A/G cg06935464 chr4:38784597 TLR10 -0.49 -7.51 -0.38 5.31e-13 Breast cancer; LIHC cis rs9911578 1.000 rs4482353 chr17:56896834 A/G cg12560992 chr17:57184187 TRIM37 0.97 17.46 0.69 2.94e-49 Intelligence (multi-trait analysis); LIHC cis rs2952156 0.920 rs732083 chr17:37834367 G/A cg07936489 chr17:37558343 FBXL20 -0.38 -5.77 -0.3 1.79e-8 Asthma; LIHC cis rs7589728 0.858 rs79992736 chr2:88530575 A/C cg07952391 chr2:88470173 THNSL2 0.68 6.53 0.33 2.42e-10 Plasma clusterin levels; LIHC cis rs778371 0.915 rs748002 chr2:233757679 G/A cg08000102 chr2:233561755 GIGYF2 -0.85 -13.2 -0.58 2e-32 Schizophrenia; LIHC cis rs1008375 0.931 rs6813374 chr4:17649494 T/C cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2153535 0.563 rs1796687 chr6:8536118 C/G cg21535247 chr6:8435926 SLC35B3 0.61 8.16 0.4 6.57e-15 Motion sickness; LIHC cis rs7208859 0.725 rs7342938 chr17:29189830 A/G cg14067834 chr17:29058358 SUZ12P 0.62 6.38 0.33 5.64e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2153535 0.580 rs9392224 chr6:8472614 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg04082016 chr2:20871401 NA -0.39 -6.84 -0.35 3.65e-11 Abdominal aortic aneurysm; LIHC cis rs67311347 1.000 rs34762643 chr3:40475433 C/T cg24209194 chr3:40518798 ZNF619 0.49 7.37 0.37 1.32e-12 Renal cell carcinoma; LIHC trans rs4843747 0.671 rs4075998 chr16:88106776 G/A cg09572067 chr16:29127029 RRN3P2 0.51 8.06 0.4 1.29e-14 Menopause (age at onset); LIHC cis rs11888559 0.655 rs6726311 chr2:204043676 G/A cg24605529 chr2:203879461 NBEAL1 0.76 5.81 0.3 1.44e-8 Height; LIHC cis rs11252926 0.550 rs10904148 chr10:454551 G/T cg16346588 chr10:242978 ZMYND11 0.39 5.94 0.31 6.85e-9 Psychosis in Alzheimer's disease; LIHC cis rs8062405 0.723 rs4788077 chr16:28569764 G/C cg07451762 chr16:28383216 NA 0.4 6.98 0.35 1.58e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg10360323 chr17:41437877 NA 0.4 6.01 0.31 4.74e-9 Menopause (age at onset); LIHC cis rs765787 0.530 rs4544188 chr15:45535393 C/A cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10633746 chr17:18164442 SMCR7 0.41 6.22 0.32 1.45e-9 Pancreatic cancer; LIHC cis rs910316 0.737 rs175499 chr14:75535927 G/A cg08847533 chr14:75593920 NEK9 -0.88 -18.46 -0.71 2.83e-53 Height; LIHC cis rs9341808 0.754 rs3805907 chr6:80973665 A/G cg08355045 chr6:80787529 NA -0.36 -7.56 -0.38 3.79e-13 Sitting height ratio; LIHC cis rs9790314 0.846 rs12495310 chr3:160970956 T/A cg03342759 chr3:160939853 NMD3 -0.82 -13.51 -0.59 1.31e-33 Morning vs. evening chronotype; LIHC cis rs2976388 0.609 rs2263092 chr8:143789966 A/G cg06565975 chr8:143823917 SLURP1 0.33 6.41 0.33 4.92e-10 Urinary tract infection frequency; LIHC cis rs2066819 0.818 rs773652 chr12:56674766 G/A cg26714650 chr12:56694279 CS 1.22 14.77 0.62 1.58e-38 Psoriasis vulgaris; LIHC trans rs7618501 1.000 rs7372730 chr3:49790682 C/G cg21659725 chr3:3221576 CRBN -0.99 -19.67 -0.73 3.83e-58 Intelligence (multi-trait analysis); LIHC cis rs2191566 0.881 rs1996408 chr19:44532732 G/A cg18700516 chr19:44507157 ZNF230 -0.38 -6.38 -0.33 5.88e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs1816752 1.000 rs9507341 chr13:25006578 G/T cg22771759 chr13:24902376 NA -0.33 -6.53 -0.33 2.38e-10 Obesity-related traits; LIHC cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg05665937 chr4:1216051 CTBP1 0.46 6.09 0.31 3.11e-9 Obesity-related traits; LIHC cis rs2276314 1.000 rs8086395 chr18:33564592 C/G cg05985134 chr18:33552581 C18orf21 0.49 5.81 0.3 1.44e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.58 0.46 2.12e-19 Bipolar disorder; LIHC cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg19774624 chr17:42201019 HDAC5 -0.68 -9.77 -0.47 4.66e-20 Total body bone mineral density; LIHC cis rs6539267 0.741 rs35816179 chr12:106693710 T/C cg02476566 chr12:106696527 TCP11L2 0.45 6.04 0.31 4e-9 Tourette syndrome; LIHC cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg08888203 chr3:10149979 C3orf24 -0.52 -6.0 -0.31 4.99e-9 Alzheimer's disease; LIHC cis rs10751667 0.961 rs6597951 chr11:991530 C/T cg10932868 chr11:921992 NA 0.34 6.32 0.32 8.33e-10 Alzheimer's disease (late onset); LIHC trans rs61931739 0.517 rs12367881 chr12:34175508 T/C cg26384229 chr12:38710491 ALG10B 0.59 7.5 0.38 5.55e-13 Morning vs. evening chronotype; LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.48 8.21 0.41 4.53e-15 Height; LIHC trans rs2243480 0.901 rs778687 chr7:65835819 G/A cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs968567 1.000 rs968567 chr11:61595564 C/T cg06781209 chr11:61594997 FADS2 -0.7 -6.52 -0.33 2.59e-10 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs10791097 0.694 rs7107595 chr11:130758556 C/T cg14779329 chr11:130786720 SNX19 0.43 6.54 0.33 2.21e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg00684032 chr4:1343700 KIAA1530 0.51 7.46 0.37 7.3e-13 Obesity-related traits; LIHC cis rs1005277 0.540 rs2474598 chr10:38430296 C/T cg25427524 chr10:38739819 LOC399744 0.64 12.33 0.55 3.63e-29 Extrinsic epigenetic age acceleration; LIHC cis rs6545883 0.894 rs6545867 chr2:61651027 C/T cg14146966 chr2:61757674 XPO1 -0.44 -7.53 -0.38 4.59e-13 Tuberculosis; LIHC cis rs72781680 0.898 rs12620558 chr2:23936022 G/A cg08917208 chr2:24149416 ATAD2B 0.96 8.22 0.41 4.3e-15 Lymphocyte counts; LIHC cis rs7584330 0.738 rs4402703 chr2:238374957 T/A cg14458575 chr2:238380390 NA 0.41 6.42 0.33 4.45e-10 Prostate cancer; LIHC trans rs9747201 1.000 rs4280305 chr17:80177069 A/C cg07393940 chr7:158741817 NA 0.57 6.6 0.34 1.54e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg13525026 chr17:18061071 MYO15A 0.42 6.5 0.33 2.92e-10 Longevity; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg15076023 chr2:175260335 CIR1;SCRN3 -0.47 -6.77 -0.34 5.76e-11 Bipolar disorder; LIHC cis rs7078219 0.505 rs4409764 chr10:101284237 T/G cg06854084 chr10:101292507 NKX2-3 -0.33 -6.06 -0.31 3.63e-9 Dental caries; LIHC cis rs4423214 0.840 rs1792229 chr11:71179395 A/G cg05163923 chr11:71159392 DHCR7 -0.6 -8.07 -0.4 1.22e-14 Vitamin D levels; LIHC cis rs1403694 0.695 rs1050274 chr3:186435370 G/A cg12454167 chr3:186435060 KNG1 0.38 8.8 0.43 6.75e-17 Blood protein levels; LIHC cis rs34779708 0.741 rs34397613 chr10:35550313 A/G cg03585969 chr10:35415529 CREM 0.74 10.58 0.5 7.78e-23 Inflammatory bowel disease;Crohn's disease; LIHC cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg09455208 chr3:40491958 NA 0.35 6.8 0.34 4.77e-11 Renal cell carcinoma; LIHC cis rs9381040 0.626 rs2272986 chr6:41037778 C/T cg25110423 chr6:41068646 NFYA;LOC221442 -0.39 -6.23 -0.32 1.38e-9 Alzheimer's disease (late onset); LIHC cis rs12620999 0.941 rs4408676 chr2:238085280 C/T cg23555395 chr2:238036564 NA -0.33 -6.55 -0.33 2.16e-10 Systemic lupus erythematosus; LIHC cis rs1008375 0.932 rs12500947 chr4:17603424 C/T cg16339924 chr4:17578868 LAP3 0.5 6.72 0.34 7.6e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg22528358 chr1:107598549 PRMT6 0.69 11.21 0.52 4.59e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10504073 0.647 rs4873314 chr8:50011656 A/C cg00325661 chr8:49890786 NA 0.32 7.32 0.37 1.75e-12 Blood metabolite ratios; LIHC trans rs916888 0.610 rs199536 chr17:44820425 T/C cg22968622 chr17:43663579 NA -0.49 -7.09 -0.36 7.64e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs250677 0.687 rs2915809 chr5:148452111 A/T cg12140854 chr5:148520817 ABLIM3 -0.46 -6.21 -0.32 1.5e-9 Breast cancer; LIHC cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 11.53 0.53 3.24e-26 Alzheimer's disease; LIHC cis rs151997 1.000 rs27284 chr5:50198086 A/G cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs2153535 0.541 rs6905934 chr6:8440043 C/A cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg11987759 chr7:65425863 GUSB 0.39 6.18 0.32 1.78e-9 Aortic root size; LIHC cis rs4906332 1.000 rs11625172 chr14:103944912 G/A cg04998671 chr14:104000505 TRMT61A -0.46 -6.21 -0.32 1.53e-9 Coronary artery disease; LIHC cis rs6963495 0.818 rs73190155 chr7:105153535 T/A cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs921968 1.000 rs4672891 chr2:219271530 G/A cg02176678 chr2:219576539 TTLL4 -0.39 -5.81 -0.3 1.44e-8 Mean corpuscular hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23815043 chr16:88729854 MGC23284;MVD 0.42 6.1 0.31 2.83e-9 Pancreatic cancer; LIHC cis rs4919087 0.715 rs34787876 chr10:98999213 T/C cg25902810 chr10:99078978 FRAT1 -0.51 -5.91 -0.3 8.29e-9 Monocyte count; LIHC cis rs3772130 0.564 rs28760466 chr3:121601510 A/G cg20356878 chr3:121714668 ILDR1 0.39 6.72 0.34 7.47e-11 Cognitive performance; LIHC cis rs7615952 0.515 rs7637246 chr3:125678706 A/G cg05084668 chr3:125655381 ALG1L -0.51 -8.05 -0.4 1.36e-14 Blood pressure (smoking interaction); LIHC cis rs17776563 0.887 rs12324548 chr15:89130155 G/A cg05013243 chr15:89149849 MIR1179 0.37 6.04 0.31 3.91e-9 Thyroid hormone levels; LIHC trans rs1005277 0.579 rs2474563 chr10:38375938 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9297145 1.000 rs10953280 chr7:98763405 A/G cg05967295 chr7:98741636 SMURF1 -0.74 -11.75 -0.54 5.1e-27 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs2243480 1.000 rs4149468 chr7:65825690 T/C cg18252515 chr7:66147081 NA -1.3 -17.6 -0.69 7.78e-50 Diabetic kidney disease; LIHC cis rs6840360 0.967 rs10776524 chr4:152602585 G/A cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.42e-10 Intelligence (multi-trait analysis); LIHC cis rs6840360 0.615 rs4696095 chr4:152467243 A/G cg22705602 chr4:152727874 NA -0.32 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs5769707 0.609 rs739247 chr22:49996657 T/C cg01652190 chr22:50026171 C22orf34 -0.33 -7.38 -0.37 1.21e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs72627509 0.638 rs7658601 chr4:57781347 C/T cg26694713 chr4:57773883 REST 0.72 10.15 0.48 2.52e-21 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7520050 0.801 rs6703960 chr1:46232723 C/T cg03146154 chr1:46216737 IPP -0.48 -8.01 -0.4 1.83e-14 Red blood cell count;Reticulocyte count; LIHC cis rs72627123 0.867 rs57685514 chr14:74487592 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.75 0.3 1.97e-8 Morning vs. evening chronotype; LIHC trans rs11662586 0.517 rs11662894 chr18:77713591 G/A cg05926928 chr17:57297772 GDPD1 0.47 6.57 0.33 1.86e-10 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs3806843 0.706 rs1089305 chr5:140066306 T/C cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.29e-10 Depressive symptoms (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03736562 chr6:100016731 CCNC -0.38 -6.1 -0.31 2.85e-9 Cognitive function; LIHC cis rs6088580 0.634 rs6087587 chr20:33058628 G/T cg08999081 chr20:33150536 PIGU 0.67 13.33 0.58 6.18e-33 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10153848 chr1:31769247 SNRNP40;ZCCHC17 0.49 6.81 0.35 4.43e-11 Pancreatic cancer; LIHC cis rs72781680 0.821 rs17046004 chr2:24144873 A/G cg08917208 chr2:24149416 ATAD2B 0.64 6.4 0.33 5.15e-10 Lymphocyte counts; LIHC cis rs2303759 0.515 rs2334867 chr19:49788205 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 -0.52 -7.61 -0.38 2.78e-13 Multiple sclerosis; LIHC cis rs12908161 0.959 rs34028043 chr15:85231585 G/A cg17507749 chr15:85114479 UBE2QP1 0.67 7.7 0.38 1.45e-13 Schizophrenia; LIHC trans rs2832191 0.716 rs2249028 chr21:30365322 G/A cg14791747 chr16:20752902 THUMPD1 -0.47 -6.66 -0.34 1.08e-10 Dental caries; LIHC cis rs7520050 0.966 rs6701614 chr1:46309420 G/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2425143 0.915 rs74355238 chr20:34441541 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.49 -5.82 -0.3 1.33e-8 Blood protein levels; LIHC cis rs7520050 0.966 rs7524495 chr1:46266932 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.98 0.31 5.65e-9 Red blood cell count;Reticulocyte count; LIHC cis rs875971 1.000 rs6958484 chr7:65599446 G/A cg18876405 chr7:65276391 NA -0.39 -6.93 -0.35 2.08e-11 Aortic root size; LIHC cis rs9916302 0.706 rs11078894 chr17:37396805 C/G cg07936489 chr17:37558343 FBXL20 -0.81 -11.72 -0.54 6.7e-27 Glomerular filtration rate (creatinine); LIHC cis rs11098699 0.821 rs4833891 chr4:124231454 A/G cg09941581 chr4:124220074 SPATA5 0.32 6.52 0.33 2.6e-10 Mosquito bite size; LIHC cis rs875971 0.737 rs7803424 chr7:65880605 T/C cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs2197308 0.610 rs10880837 chr12:37864924 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.77 0.3 1.79e-8 Morning vs. evening chronotype; LIHC cis rs35110281 0.720 rs162400 chr21:44950305 A/C cg04455712 chr21:45112962 RRP1B 0.46 7.46 0.37 7.35e-13 Mean corpuscular volume; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.42 0.37 9.56e-13 Prudent dietary pattern; LIHC cis rs600806 0.850 rs1343465 chr1:109937426 T/C cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.29 -5.94 -0.31 7.15e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs12701220 0.655 rs10241018 chr7:1144774 G/C cg26769984 chr7:1090371 C7orf50 0.48 5.89 0.3 9.12e-9 Bronchopulmonary dysplasia; LIHC cis rs2842992 0.789 rs4235925 chr6:160202860 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.49 8.59 0.42 3.17e-16 Age-related macular degeneration (geographic atrophy); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13140721 chr3:100053382 NIT2 0.48 6.95 0.35 1.91e-11 Cognitive function; LIHC cis rs12602486 1.000 rs2285953 chr17:42268255 G/C cg08193365 chr17:42277699 NA 1.04 7.22 0.36 3.49e-12 Glycated hemoglobin levels; LIHC cis rs1003719 0.715 rs2835639 chr21:38537016 G/C cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs2562456 0.876 rs11085468 chr19:21751889 C/T cg23367146 chr19:21773418 NA 0.38 5.86 0.3 1.07e-8 Pain; LIHC cis rs3015497 0.594 rs35637875 chr14:51132533 T/G cg09863266 chr14:51125203 SAV1 -0.4 -6.45 -0.33 3.92e-10 Mean platelet volume; LIHC cis rs473651 0.904 rs508274 chr2:239337723 G/A cg18131467 chr2:239335373 ASB1 1.05 19.59 0.73 8.14e-58 Multiple system atrophy; LIHC cis rs7923837 0.651 rs1573051 chr10:94387334 T/C cg25506282 chr10:94462361 NA 0.34 5.75 0.3 2e-8 Body mass index;Multiple sclerosis; LIHC cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg19723775 chr5:179050963 HNRNPH1 0.41 6.39 0.33 5.49e-10 Lung cancer; LIHC cis rs9788682 1.000 rs12441354 chr15:78821016 G/A cg06917634 chr15:78832804 PSMA4 -0.52 -7.46 -0.37 7.05e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13615036 chr15:91475826 UNC45A;HDDC3 -0.47 -6.4 -0.33 5.25e-10 Systolic blood pressure; LIHC cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg10802521 chr3:52805072 NEK4 -0.45 -7.56 -0.38 3.75e-13 Bipolar disorder; LIHC cis rs1816752 1.000 rs1816752 chr13:24980949 A/G cg02811702 chr13:24901961 NA 0.27 6.14 0.32 2.3e-9 Obesity-related traits; LIHC cis rs9457247 1.000 rs400837 chr6:167411008 T/C cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC cis rs875971 0.619 rs12533585 chr7:65984605 G/C cg11764359 chr7:65958608 NA 0.72 10.98 0.51 3.13e-24 Aortic root size; LIHC cis rs7539409 0.604 rs6689821 chr1:84316605 A/G cg10977910 chr1:84465055 TTLL7 0.72 7.17 0.36 4.68e-12 Alzheimer's disease; LIHC cis rs7903847 0.620 rs11189165 chr10:99123457 A/G cg20016023 chr10:99160130 RRP12 -0.41 -6.34 -0.32 7.3e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.73 0.39 1.18e-13 Prudent dietary pattern; LIHC cis rs589448 0.967 rs2617835 chr12:69753420 C/A cg14784868 chr12:69753453 YEATS4 0.99 23.08 0.78 1.05e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs2710642 0.540 rs11893614 chr2:62861661 A/G cg17519650 chr2:63277830 OTX1 0.47 6.88 0.35 2.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs1559088 0.749 rs10405757 chr19:33616526 C/A cg17764715 chr19:33622953 WDR88 0.47 6.85 0.35 3.45e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4788570 0.615 rs2052584 chr16:71688977 A/G cg06353428 chr16:71660113 MARVELD3 -1.37 -14.61 -0.62 6.95e-38 Intelligence (multi-trait analysis); LIHC cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg06453172 chr10:134556979 INPP5A -0.65 -8.23 -0.41 4.09e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2012796 0.743 rs61986598 chr14:81856865 G/A cg02996355 chr14:81879375 NA 0.72 11.76 0.54 4.74e-27 Night sleep phenotypes; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg00091569 chr3:40428383 ENTPD3 0.39 6.57 0.33 1.91e-10 Renal cell carcinoma; LIHC cis rs875971 0.545 rs1796217 chr7:66085918 A/G cg11764359 chr7:65958608 NA -0.62 -8.96 -0.44 2.09e-17 Aortic root size; LIHC cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg02990361 chr1:107599529 PRMT6 -0.61 -9.92 -0.47 1.47e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg22105103 chr4:187893119 NA -0.34 -8.38 -0.41 1.44e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs9916302 0.904 rs55660616 chr17:37684990 C/A cg00129232 chr17:37814104 STARD3 -0.42 -6.72 -0.34 7.42e-11 Glomerular filtration rate (creatinine); LIHC cis rs7078219 0.505 rs10883362 chr10:101286984 C/T cg06854084 chr10:101292507 NKX2-3 -0.32 -5.86 -0.3 1.06e-8 Dental caries; LIHC cis rs3806843 0.900 rs2262576 chr5:140135536 T/C cg26395211 chr5:140044315 WDR55 0.39 5.86 0.3 1.1e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs7937890 0.559 rs2597201 chr11:14485404 T/C cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs7666738 0.830 rs921522 chr4:98841608 C/T cg05340658 chr4:99064831 C4orf37 0.63 11.09 0.51 1.25e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs9818758 0.607 rs80170003 chr3:48951640 T/C cg07636037 chr3:49044803 WDR6 -0.84 -7.08 -0.36 8.28e-12 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs62103177 0.683 rs62101232 chr18:77722454 T/C cg05926928 chr17:57297772 GDPD1 0.8 8.42 0.41 1.08e-15 Opioid sensitivity; LIHC cis rs9911578 0.967 rs2643124 chr17:56741672 T/C cg05425664 chr17:57184151 TRIM37 -0.59 -8.72 -0.43 1.21e-16 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg06640241 chr16:89574553 SPG7 0.81 14.81 0.63 1.05e-38 Multiple myeloma (IgH translocation); LIHC cis rs9381040 0.610 rs9394758 chr6:41017821 C/T cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.26 -0.32 1.12e-9 Alzheimer's disease (late onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24672547 chr12:6977222 TPI1 -0.43 -6.25 -0.32 1.19e-9 Pancreatic cancer; LIHC cis rs875971 0.545 rs73142265 chr7:65699497 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.27 0.37 2.45e-12 Aortic root size; LIHC cis rs12500138 0.850 rs57692509 chr4:166208733 A/G cg25064052 chr4:166216151 KLHL2 -0.63 -5.89 -0.3 9.1e-9 Cognitive function; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg10217327 chr6:118973057 C6orf204 0.7 7.26 0.37 2.67e-12 Diastolic blood pressure; LIHC cis rs6089829 0.851 rs4809460 chr20:61661355 T/C cg08564027 chr20:61660810 NA 0.4 7.67 0.38 1.84e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg06466757 chr4:1255808 NA 0.35 5.86 0.3 1.06e-8 Obesity-related traits; LIHC cis rs9916302 0.904 rs612194 chr17:37442707 T/A cg00129232 chr17:37814104 STARD3 0.39 6.23 0.32 1.34e-9 Glomerular filtration rate (creatinine); LIHC cis rs801193 0.844 rs732465 chr7:65998450 T/C cg14393609 chr7:65229607 NA 0.35 5.76 0.3 1.92e-8 Aortic root size; LIHC cis rs6500602 0.767 rs8060219 chr16:4480158 T/A cg08645402 chr16:4508243 NA 0.36 6.85 0.35 3.49e-11 Schizophrenia; LIHC cis rs908922 0.676 rs1123567 chr1:152516023 G/A cg20991723 chr1:152506922 NA 0.55 9.39 0.45 8.94e-19 Hair morphology; LIHC cis rs1401999 1.000 rs6805913 chr3:183662924 T/G cg05044414 chr3:183734942 ABCC5 0.34 6.07 0.31 3.33e-9 Anterior chamber depth; LIHC cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg22907277 chr7:1156413 C7orf50 0.45 6.59 0.34 1.69e-10 Longevity;Endometriosis; LIHC cis rs8180040 0.764 rs4682852 chr3:47177772 C/T cg16586182 chr3:47516702 SCAP -0.51 -9.45 -0.45 5.62e-19 Colorectal cancer; LIHC cis rs4409675 0.576 rs6662916 chr1:28219873 G/T cg23691781 chr1:28212827 C1orf38 0.32 7.77 0.39 9.38e-14 Corneal astigmatism; LIHC cis rs929354 0.772 rs2301914 chr7:157000176 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.1 0.55 2.72e-28 Body mass index; LIHC cis rs12744310 1.000 rs12731400 chr1:41761352 T/C cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs3008870 1.000 rs2815348 chr1:67472165 G/C cg08660285 chr1:67390436 MIER1;WDR78 0.93 15.92 0.65 4.54e-43 Lymphocyte percentage of white cells; LIHC cis rs17666538 0.585 rs1669615 chr8:616665 T/C cg13264159 chr8:625131 ERICH1 -0.62 -6.31 -0.32 8.6e-10 IgG glycosylation; LIHC cis rs9399135 0.967 rs4895436 chr6:135295001 G/A cg22676075 chr6:135203613 NA 0.4 6.47 0.33 3.49e-10 Red blood cell count; LIHC cis rs5769707 0.667 rs4824069 chr22:50030325 T/C cg01652190 chr22:50026171 C22orf34 -0.34 -7.65 -0.38 2.12e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs3768617 0.510 rs20557 chr1:183093875 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Fuchs's corneal dystrophy; LIHC cis rs2380220 0.720 rs9374178 chr6:95979974 G/T cg15832292 chr6:96025679 MANEA 0.61 7.72 0.39 1.27e-13 Behavioural disinhibition (generation interaction); LIHC cis rs67311347 1.000 rs11129876 chr3:40401636 C/T cg00656387 chr3:40428638 ENTPD3 -0.38 -6.43 -0.33 4.29e-10 Renal cell carcinoma; LIHC cis rs2841233 0.681 rs2582558 chr14:105347488 A/G cg16576083 chr14:105354267 KIAA0284 -0.45 -7.58 -0.38 3.23e-13 IgG glycosylation; LIHC cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.13 10.89 0.51 6.8e-24 Platelet count; LIHC cis rs4819052 0.851 rs9979545 chr21:46679805 G/A cg22633049 chr21:46681294 NA -0.35 -6.02 -0.31 4.48e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1577917 0.958 rs13207354 chr6:86700263 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -9.63 -0.46 1.43e-19 Response to antipsychotic treatment; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04122790 chr1:229762148 URB2;TAF5L 0.48 7.02 0.35 1.21e-11 Cognitive function; LIHC cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.88 0.3 9.63e-9 Aortic root size; LIHC cis rs9309711 0.961 rs11678655 chr2:3476234 T/G cg04359351 chr2:3481828 TTC15 0.29 5.71 0.3 2.44e-8 Neurofibrillary tangles; LIHC cis rs7618501 0.538 rs9856572 chr3:50109073 A/T cg21467203 chr3:49911342 NA 0.43 7.72 0.39 1.27e-13 Intelligence (multi-trait analysis); LIHC cis rs9682041 0.696 rs11917147 chr3:170088448 C/T cg11886554 chr3:170076028 SKIL 0.66 5.99 0.31 5.18e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs4906332 0.966 rs2065016 chr14:103879656 T/A cg19000871 chr14:103996768 TRMT61A -0.45 -7.65 -0.38 2e-13 Coronary artery disease; LIHC cis rs739401 0.611 rs450817 chr11:3056712 A/G cg08508325 chr11:3079039 CARS -0.32 -6.73 -0.34 7.14e-11 Longevity; LIHC cis rs9649465 0.704 rs665867 chr7:123432329 A/G cg03229431 chr7:123269106 ASB15 0.4 8.55 0.42 4.22e-16 Migraine; LIHC cis rs2404602 0.692 rs4442773 chr15:77031633 T/C cg03037974 chr15:76606532 NA 0.75 14.57 0.62 9.51e-38 Blood metabolite levels; LIHC cis rs4819052 0.851 rs2838842 chr21:46669217 C/T cg22633049 chr21:46681294 NA -0.37 -6.43 -0.33 4.26e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs58688157 0.705 rs7112149 chr11:595890 G/A cg16486109 chr11:613632 IRF7 0.58 6.23 0.32 1.36e-9 Systemic lupus erythematosus; LIHC cis rs6701037 0.512 rs4650716 chr1:175128711 C/A cg00321850 chr1:175162397 KIAA0040 0.44 7.2 0.36 3.87e-12 Alcohol dependence; LIHC cis rs644799 0.687 rs11021318 chr11:95522996 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.7 0.57 1.59e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7216064 0.684 rs7406031 chr17:66021753 C/T cg12091567 chr17:66097778 LOC651250 0.84 13.96 0.6 2.4e-35 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10384784 chr10:25012964 ARHGAP21 0.43 6.39 0.33 5.35e-10 Pancreatic cancer; LIHC cis rs7208859 0.623 rs7503542 chr17:29073830 A/C cg13385521 chr17:29058706 SUZ12P 0.82 8.25 0.41 3.52e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs765787 0.530 rs11636404 chr15:45535861 C/G cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.76 -0.3 1.86e-8 Uric acid levels; LIHC cis rs1475911 0.708 rs8129075 chr21:43523430 G/T cg24372256 chr21:43528868 UMODL1;C21orf128 -0.35 -5.74 -0.3 2.09e-8 IgG glycosylation; LIHC trans rs3812049 0.784 rs1560637 chr5:127448066 A/C cg16011800 chr17:1958478 HIC1 -0.53 -7.52 -0.38 4.94e-13 Lymphocyte counts;Red cell distribution width; LIHC cis rs9902453 0.933 rs1128156 chr17:28513176 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.2 0.45 3.59e-18 Coffee consumption (cups per day); LIHC cis rs75908454 1.000 rs78270891 chr6:169877832 T/C cg19338460 chr6:170058176 WDR27 -0.83 -7.6 -0.38 2.89e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs1401999 1.000 rs3805108 chr3:183691650 T/C cg01324343 chr3:183735012 ABCC5 0.76 12.89 0.57 2.9e-31 Anterior chamber depth; LIHC cis rs68170813 0.559 rs17428126 chr7:106897037 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg19357918 chr11:63953256 STIP1 -0.44 -6.44 -0.33 4.17e-10 Bipolar disorder; LIHC cis rs2066819 1.000 rs74673257 chr12:56638077 T/C cg26734620 chr12:56694298 CS 1.23 10.54 0.5 1.14e-22 Psoriasis vulgaris; LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs7520050 0.966 rs6675726 chr1:46560643 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.8 0.3 1.48e-8 Red blood cell count;Reticulocyte count; LIHC cis rs6570726 0.557 rs403956 chr6:145829956 T/C cg23711669 chr6:146136114 FBXO30 0.63 9.83 0.47 2.95e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2236918 1.000 rs2797605 chr1:242025245 A/T cg17736920 chr1:242011382 EXO1 0.6 8.63 0.42 2.43e-16 Menopause (age at onset); LIHC cis rs9393777 0.545 rs56303243 chr6:26485727 G/A cg12826209 chr6:26865740 GUSBL1 0.65 6.79 0.34 5.06e-11 Intelligence (multi-trait analysis); LIHC cis rs754466 1.000 rs12220328 chr10:79681482 G/C cg17075019 chr10:79541650 NA -0.62 -8.32 -0.41 2.1e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg06481639 chr22:41940642 POLR3H -0.72 -6.74 -0.34 6.5500000000000006e-11 Vitiligo; LIHC cis rs72634258 0.554 rs12741937 chr1:7897622 A/T cg26816564 chr1:7831052 VAMP3 0.67 5.78 0.3 1.65e-8 Inflammatory bowel disease; LIHC cis rs9814567 1.000 rs62271513 chr3:134298412 T/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.88 0.3 9.6e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs16828019 0.704 rs34486565 chr1:41522510 C/T cg03387723 chr1:41708464 SCMH1 -0.4 -6.46 -0.33 3.63e-10 Intelligence (multi-trait analysis); LIHC cis rs7246657 0.943 rs2303131 chr19:37936025 G/A cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs2273156 0.706 rs12881698 chr14:35503505 G/A cg16230307 chr14:35515116 FAM177A1 -0.43 -6.23 -0.32 1.39e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs7208859 0.623 rs12103508 chr17:29086781 T/G cg13385521 chr17:29058706 SUZ12P 0.83 8.21 0.41 4.55e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504073 0.584 rs115370638 chr8:49916452 A/G cg00325661 chr8:49890786 NA 0.38 9.14 0.44 5.79e-18 Blood metabolite ratios; LIHC cis rs17376456 0.877 rs10476601 chr5:93402522 G/A cg25358565 chr5:93447407 FAM172A 1.12 10.25 0.48 1.1e-21 Diabetic retinopathy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20540327 chr15:72668275 HEXA;C15orf34 0.44 6.49 0.33 3.04e-10 Pancreatic cancer; LIHC cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg10360323 chr17:41437877 NA 0.4 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg09417038 chr21:47716443 C21orf57 -0.47 -7.22 -0.36 3.43e-12 Testicular germ cell tumor; LIHC cis rs9733 0.596 rs11586422 chr1:150679358 C/T cg18016565 chr1:150552671 MCL1 0.58 11.45 0.53 6.54e-26 Tonsillectomy; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg21774865 chr7:157009442 UBE3C 0.34 6.09 0.31 3e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1559088 0.842 rs12977993 chr19:33580453 T/A cg27124370 chr19:33622961 WDR88 0.54 8.71 0.43 1.3e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2073300 1.000 rs6137960 chr20:23442886 G/A cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2204008 0.748 rs11514352 chr12:38246954 C/T cg26384229 chr12:38710491 ALG10B 0.87 10.83 0.51 1.06e-23 Bladder cancer; LIHC cis rs12594515 1.000 rs7162201 chr15:45992658 A/C cg06207120 chr15:45996521 NA 0.32 6.02 0.31 4.55e-9 Waist circumference;Weight; LIHC cis rs1707322 0.752 rs4660880 chr1:46111040 C/T cg03146154 chr1:46216737 IPP 0.58 9.78 0.47 4.45e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.593 rs16921626 chr8:58040359 C/T cg20607798 chr8:58055168 NA 0.48 6.61 0.34 1.5e-10 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.08 0.31 3.29e-9 Menopause (age at onset); LIHC trans rs61931739 0.534 rs10844774 chr12:34166764 C/T cg26384229 chr12:38710491 ALG10B 0.59 7.5 0.38 5.55e-13 Morning vs. evening chronotype; LIHC cis rs17384381 1.000 rs12138852 chr1:85878208 C/T cg16011679 chr1:85725395 C1orf52 0.8 8.49 0.42 6.31e-16 Lobe attachment (rater-scored or self-reported); LIHC trans rs561341 0.700 rs79272796 chr17:30226974 T/C cg20587970 chr11:113659929 NA -0.51 -6.48 -0.33 3.11e-10 Hip circumference adjusted for BMI; LIHC trans rs2727020 0.894 rs11040333 chr11:49346332 G/A cg18944383 chr4:111397179 ENPEP 0.28 6.41 0.33 4.73e-10 Coronary artery disease; LIHC cis rs2067615 0.579 rs4964486 chr12:107140790 A/G cg15890332 chr12:107067104 RFX4 0.26 6.08 0.31 3.26e-9 Heart rate; LIHC cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg15691649 chr6:25882328 NA -0.55 -8.03 -0.4 1.62e-14 Blood metabolite levels; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.6 0.38 2.95e-13 Height; LIHC trans rs3809912 0.693 rs12605081 chr18:12999964 A/G cg02139827 chr21:34404457 NA 0.24 6.04 0.31 4.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7412746 0.587 rs11204722 chr1:150730184 A/C cg17724175 chr1:150552817 MCL1 -0.42 -8.42 -0.41 1.08e-15 Melanoma; LIHC cis rs1997103 0.822 rs940878 chr7:55419663 A/G cg17469321 chr7:55412551 NA 0.51 7.21 0.36 3.52e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs918629 0.530 rs3777190 chr5:95247972 A/G cg10483112 chr5:95245456 ELL2 0.36 6.65 0.34 1.14e-10 IgG glycosylation; LIHC cis rs17685 0.712 rs6464994 chr7:75784668 C/T cg01364799 chr7:75623366 TMEM120A -0.41 -6.12 -0.31 2.5e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7799006 0.527 rs73039284 chr7:2221583 C/G cg04267008 chr7:1944627 MAD1L1 -0.42 -6.51 -0.33 2.76e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg11062466 chr8:58055876 NA 0.5 6.3 0.32 9.32e-10 Developmental language disorder (linguistic errors); LIHC cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.55 -6.53 -0.33 2.39e-10 Diastolic blood pressure; LIHC cis rs709400 0.663 rs11628969 chr14:103940911 G/A cg26031613 chr14:104095156 KLC1 0.71 9.43 0.45 6.34e-19 Body mass index; LIHC cis rs2243480 1.000 rs778679 chr7:65840911 A/G cg12463550 chr7:65579703 CRCP 0.65 6.8 0.34 4.75e-11 Diabetic kidney disease; LIHC cis rs10861342 0.892 rs74971338 chr12:105499757 C/A cg23923672 chr12:105501055 KIAA1033 0.65 7.66 0.38 1.88e-13 IgG glycosylation; LIHC cis rs2795502 0.882 rs2744093 chr10:43339243 A/G cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg14257396 chr1:107603778 NA 0.36 5.77 0.3 1.75e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9929218 1.000 rs13333528 chr16:68790502 C/T cg01231543 chr16:68741748 NA 0.37 5.76 0.3 1.84e-8 Colorectal cancer; LIHC cis rs6570726 0.599 rs9376951 chr6:145898911 C/T cg13319975 chr6:146136371 FBXO30 -0.58 -8.97 -0.44 2.06e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg24846343 chr22:24311635 DDTL 0.61 11.73 0.54 5.99e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs10838798 0.504 rs1483123 chr11:48326773 G/A cg15704280 chr7:45808275 SEPT13 -0.42 -6.37 -0.33 6.22e-10 Height; LIHC cis rs9902453 1.000 rs8065059 chr17:28417376 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.63 -9.62 -0.46 1.5700000000000001e-19 Coffee consumption (cups per day); LIHC cis rs11711311 0.955 rs2124105 chr3:113406003 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.39 6.66 0.34 1.1e-10 IgG glycosylation; LIHC cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg18876405 chr7:65276391 NA 0.55 9.21 0.45 3.36e-18 Aortic root size; LIHC cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg23205692 chr1:25664452 TMEM50A 0.41 6.59 0.34 1.65e-10 Erythrocyte sedimentation rate; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg04282497 chr4:82350883 RASGEF1B -0.41 -6.4 -0.33 5.01e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7845219 0.544 rs10956932 chr8:95948202 C/T cg16049864 chr8:95962084 TP53INP1 0.4 6.74 0.34 6.64e-11 Type 2 diabetes; LIHC cis rs25645 0.502 rs7223318 chr17:38108553 G/C cg17467752 chr17:38218738 THRA 0.41 6.09 0.31 2.95e-9 Myeloid white cell count; LIHC cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs1868673 0.503 rs9867338 chr3:150242048 C/A cg10752315 chr3:150238463 NA 0.3 5.92 0.3 7.73e-9 Waist circumference; LIHC cis rs2637266 0.935 rs7900900 chr10:78367383 A/T cg18941641 chr10:78392320 NA 0.29 6.35 0.32 6.91e-10 Pulmonary function; LIHC cis rs9549260 0.709 rs4943795 chr13:41173433 C/T cg21288729 chr13:41239152 FOXO1 -0.59 -9.14 -0.44 5.61e-18 Red blood cell count; LIHC cis rs3768617 0.510 rs10911239 chr1:183062450 T/C ch.1.3577855R chr1:183094577 LAMC1 0.63 10.94 0.51 4.35e-24 Fuchs's corneal dystrophy; LIHC cis rs1048238 0.545 rs848199 chr1:16292742 C/T cg00529422 chr1:16285251 ZBTB17 0.35 6.91 0.35 2.32e-11 Systolic blood pressure; LIHC trans rs17711722 0.510 rs11767457 chr7:65290615 C/T cg10756647 chr7:56101905 PSPH -0.47 -6.89 -0.35 2.66e-11 Calcium levels; LIHC cis rs1577917 0.916 rs12203358 chr6:86603224 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.39 -0.49 3.56e-22 Response to antipsychotic treatment; LIHC cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.93 9.08 0.44 8.96e-18 Platelet count; LIHC cis rs7903847 0.642 rs11189192 chr10:99149403 G/A cg20016023 chr10:99160130 RRP12 -0.42 -6.53 -0.33 2.32e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs6952808 0.531 rs3800922 chr7:2184505 A/G cg21782813 chr7:2030301 MAD1L1 0.36 6.09 0.31 3.12e-9 Bipolar disorder and schizophrenia; LIHC cis rs9790314 0.875 rs163327 chr3:161062724 A/G cg03342759 chr3:160939853 NMD3 -0.73 -9.07 -0.44 9.32e-18 Morning vs. evening chronotype; LIHC cis rs2439831 0.850 rs16950562 chr15:44036364 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.55 6.72 0.34 7.69e-11 Lung cancer in ever smokers; LIHC cis rs6701037 0.625 rs34270511 chr1:175128543 C/T cg17845761 chr1:175162550 KIAA0040 -0.43 -7.19 -0.36 4.16e-12 Alcohol dependence; LIHC cis rs4820539 1.000 rs13054985 chr22:23458577 G/A cg14186256 chr22:23484241 RTDR1 0.95 19.97 0.73 2.32e-59 Bone mineral density; LIHC cis rs3812831 0.599 rs428637 chr13:114927139 T/G cg06611532 chr13:114900021 NA 0.37 6.83 0.35 3.81e-11 Schizophrenia; LIHC cis rs9486719 1.000 rs3798289 chr6:97023632 T/C cg06623918 chr6:96969491 KIAA0776 -0.7 -7.21 -0.36 3.53e-12 Migraine;Coronary artery disease; LIHC cis rs4727027 0.933 rs1058059 chr7:148879134 A/T cg23583168 chr7:148888333 NA -0.74 -10.63 -0.5 5.22e-23 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg03806693 chr22:41940476 POLR3H 0.97 10.53 0.49 1.19e-22 Vitiligo; LIHC cis rs78545713 0.649 rs114015443 chr6:26221979 A/G cg16070018 chr6:26224392 HIST1H3E 0.8 7.54 0.38 4.2e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs965469 0.948 rs2236094 chr20:3260368 C/G cg25506879 chr20:3388711 C20orf194 0.54 6.52 0.33 2.45e-10 IFN-related cytopenia; LIHC cis rs365132 0.517 rs6881002 chr5:176336755 T/C cg16309518 chr5:176445507 NA 0.52 9.86 0.47 2.43e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs611744 0.967 rs685690 chr8:109192145 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC trans rs1005277 0.579 rs1780145 chr10:38537070 A/G cg27523141 chr10:43048294 ZNF37B 0.39 6.6 0.34 1.59e-10 Extrinsic epigenetic age acceleration; LIHC cis rs10751667 0.961 rs7479171 chr11:926809 G/A ch.11.42038R chr11:967971 AP2A2 0.59 10.89 0.51 6.5e-24 Alzheimer's disease (late onset); LIHC cis rs778371 0.788 rs4973569 chr2:233767037 A/G cg08000102 chr2:233561755 GIGYF2 -0.73 -9.0 -0.44 1.56e-17 Schizophrenia; LIHC cis rs3806843 0.900 rs2337983 chr5:140136808 G/A cg26395211 chr5:140044315 WDR55 0.41 6.09 0.31 2.99e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs769267 0.965 rs2074550 chr19:19387743 A/C cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs11792861 0.926 rs75472294 chr9:111804239 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.44 0.42 9.06e-16 Menarche (age at onset); LIHC cis rs919433 0.617 rs700642 chr2:198600730 G/T cg03934865 chr2:198174659 NA -0.45 -6.65 -0.34 1.17e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17102423 0.594 rs2781373 chr14:65568215 G/A cg16583315 chr14:65563665 MAX -0.42 -8.43 -0.41 9.65e-16 Obesity-related traits; LIHC cis rs3845702 0.736 rs72960701 chr2:180851202 A/T cg01881094 chr2:180872142 CWC22 1.14 10.02 0.48 6.68e-21 Schizophrenia; LIHC cis rs10416265 0.528 rs28654374 chr19:33613610 G/A cg17764715 chr19:33622953 WDR88 0.48 6.36 0.33 6.28e-10 Bone properties (heel); LIHC cis rs1003719 0.715 rs9981715 chr21:38499610 C/G cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.23 -0.52 4.16e-25 Eye color traits; LIHC cis rs12497850 0.865 rs7649458 chr3:48920127 C/T cg06212747 chr3:49208901 KLHDC8B 0.57 7.36 0.37 1.42e-12 Parkinson's disease; LIHC cis rs807029 0.533 rs67813203 chr10:102738551 A/G cg27255678 chr10:102756921 LZTS2 0.52 7.31 0.37 1.85e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1997103 1.000 rs4590393 chr7:55408990 C/T cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs5769765 0.862 rs9616384 chr22:50313082 C/T cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs4665809 0.793 rs6546715 chr2:26261520 G/A cg04944784 chr2:26401820 FAM59B -0.68 -8.71 -0.43 1.37e-16 Gut microbiome composition (summer); LIHC cis rs9921222 0.500 rs8046256 chr16:393948 C/T cg00101154 chr16:420108 MRPL28 -0.75 -10.45 -0.49 2.25e-22 Bone mineral density (spine);Bone mineral density; LIHC cis rs875971 0.862 rs7786892 chr7:65628876 G/A cg18876405 chr7:65276391 NA -0.36 -6.37 -0.33 5.93e-10 Aortic root size; LIHC cis rs908922 0.676 rs12132469 chr1:152491856 G/T cg23254163 chr1:152506842 NA 0.22 5.8 0.3 1.48e-8 Hair morphology; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09655887 chr7:133083962 EXOC4 0.38 6.88 0.35 2.93e-11 Hepatitis; LIHC cis rs6942756 0.713 rs691807 chr7:129076203 G/C cg02491457 chr7:128862824 NA -0.55 -8.4 -0.41 1.21e-15 White matter hyperintensity burden; LIHC cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg03188948 chr7:1209495 NA 0.78 6.17 0.32 1.89e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7582720 1.000 rs72936881 chr2:203794262 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01390039 chr16:89315293 NA 0.44 6.22 0.32 1.44e-9 Longevity; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg12517452 chr5:52084045 ITGA1;PELO -0.53 -6.94 -0.35 1.96e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2292864 0.681 rs35735886 chr17:45374277 G/T cg18085866 chr17:45331354 ITGB3 -0.66 -6.96 -0.35 1.71e-11 Left atrial antero-posterior diameter; LIHC cis rs8180040 0.726 rs13094672 chr3:47149439 C/T cg02527881 chr3:46936655 PTH1R -0.31 -5.98 -0.31 5.69e-9 Colorectal cancer; LIHC cis rs7617773 0.817 rs17647717 chr3:48305456 C/T cg11946769 chr3:48343235 NME6 0.9 10.83 0.51 1.11e-23 Coronary artery disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg14620208 chr9:140652685 EHMT1 0.49 6.62 0.34 1.42e-10 Hepatitis; LIHC cis rs736408 0.716 rs2239549 chr3:52823126 C/T cg18404041 chr3:52824283 ITIH1 -0.64 -10.77 -0.5 1.67e-23 Bipolar disorder; LIHC cis rs8180040 0.620 rs11707736 chr3:47069504 G/T cg27129171 chr3:47204927 SETD2 -0.55 -9.14 -0.44 5.79e-18 Colorectal cancer; LIHC cis rs4586057 0.514 rs11186350 chr10:92649368 G/T cg14313238 chr10:92632228 RPP30 0.36 6.04 0.31 4.03e-9 Economic and political preferences (time); LIHC cis rs10744422 0.748 rs2292138 chr12:123339712 A/G cg18912006 chr12:123335444 HIP1R -0.64 -7.67 -0.38 1.78e-13 Schizophrenia; LIHC cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg22903471 chr2:27725779 GCKR -0.5 -8.6 -0.42 2.87e-16 Menopause (age at onset); LIHC cis rs12022452 0.591 rs12042242 chr1:40993873 A/G cg25568243 chr1:40974465 DEM1 -0.45 -6.1 -0.31 2.82e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6540556 0.723 rs3766619 chr1:209895298 C/G cg05527609 chr1:210001259 C1orf107 -0.56 -7.67 -0.38 1.81e-13 Red blood cell count; LIHC cis rs8141529 0.719 rs2097461 chr22:29191879 T/C cg02153584 chr22:29168773 CCDC117 0.57 9.31 0.45 1.64e-18 Lymphocyte counts; LIHC cis rs3768617 0.782 rs12143211 chr1:182990172 C/G ch.1.3577855R chr1:183094577 LAMC1 0.49 7.89 0.39 4.16e-14 Fuchs's corneal dystrophy; LIHC cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg06873352 chr17:61820015 STRADA 0.58 8.87 0.43 4.25e-17 Height; LIHC cis rs11864453 0.647 rs7194397 chr16:72128299 C/T cg16558253 chr16:72132732 DHX38 -0.41 -6.66 -0.34 1.1e-10 Fibrinogen levels; LIHC cis rs7312933 0.703 rs7957471 chr12:42545591 G/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 7.98 0.4 2.16e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs67311347 0.869 rs6790495 chr3:40366770 C/T cg13409248 chr3:40428643 ENTPD3 0.42 6.76 0.34 6.05e-11 Renal cell carcinoma; LIHC cis rs722599 0.639 rs12882676 chr14:75272433 A/G cg08847533 chr14:75593920 NEK9 0.51 7.7 0.38 1.46e-13 IgG glycosylation; LIHC cis rs4820294 0.669 rs1894532 chr22:38059750 T/C cg00292662 chr22:38071168 LGALS1 0.38 6.32 0.32 7.99e-10 Fat distribution (HIV); LIHC cis rs655641 0.954 rs637304 chr11:85685166 A/G cg09030501 chr11:85779252 PICALM -0.51 -6.01 -0.31 4.66e-9 Platelet count; LIHC cis rs6426558 0.537 rs4351610 chr1:227325245 A/G cg10327440 chr1:227177885 CDC42BPA -0.45 -6.89 -0.35 2.74e-11 Neutrophil percentage of white cells; LIHC cis rs561341 0.941 rs72825736 chr17:30330286 G/A cg00745463 chr17:30367425 LRRC37B -0.79 -5.92 -0.3 7.98e-9 Hip circumference adjusted for BMI; LIHC cis rs12464559 0.579 rs10185966 chr2:152582523 A/G cg01189475 chr2:152685088 ARL5A 0.67 7.69 0.38 1.61e-13 Response to cognitive-behavioural therapy in anxiety disorder; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26118675 chr2:96256841 TRIM43 0.42 6.06 0.31 3.53e-9 Systolic blood pressure; LIHC cis rs2991971 0.967 rs7526665 chr1:46005832 G/T cg24296786 chr1:45957014 TESK2 0.51 7.66 0.38 1.93e-13 High light scatter reticulocyte count; LIHC trans rs875971 1.000 rs1968225 chr7:65874773 T/C cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs780096 0.526 rs780117 chr2:27698343 C/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.09 -0.31 3.09e-9 Total body bone mineral density; LIHC cis rs875971 0.520 rs12666485 chr7:65625122 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.5 0.38 5.5e-13 Aortic root size; LIHC cis rs2273156 1.000 rs12050404 chr14:35461870 G/A cg16230307 chr14:35515116 FAM177A1 -0.41 -6.04 -0.31 3.96e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC trans rs8073060 0.586 rs2011897 chr17:34054408 A/T cg19694781 chr19:47549865 TMEM160 1.23 12.75 0.57 9.88e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs8017423 0.967 rs4904657 chr14:90721600 A/G cg14092571 chr14:90743983 NA -0.38 -6.09 -0.31 2.97e-9 Mortality in heart failure; LIHC cis rs644799 0.540 rs10831419 chr11:95478037 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.55 7.05 0.36 9.72e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs66569888 0.507 rs11673736 chr2:106886935 T/C cg16099169 chr2:106886729 NA -0.71 -13.2 -0.58 1.94e-32 Facial morphology (factor 23); LIHC cis rs11690935 0.632 rs6723259 chr2:172622527 A/C cg13550731 chr2:172543902 DYNC1I2 0.63 11.5 0.53 4.27e-26 Schizophrenia; LIHC cis rs9457247 0.967 rs388406 chr6:167409562 A/G cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 0.43 6.58 0.34 1.81e-10 Total body bone mineral density; LIHC cis rs7223966 1.000 rs113134232 chr17:61715461 G/A cg05941027 chr17:61774174 LIMD2 0.34 6.43 0.33 4.39e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs17253792 0.822 rs13379343 chr14:56050205 G/A cg01858014 chr14:56050164 KTN1 -0.75 -8.07 -0.4 1.22e-14 Putamen volume; LIHC cis rs11690935 1.000 rs3795999 chr2:172544483 A/G cg13550731 chr2:172543902 DYNC1I2 0.92 18.0 0.7 1.88e-51 Schizophrenia; LIHC trans rs931812 0.825 rs55818461 chr8:101899229 T/C cg20993868 chr7:22813445 NA 0.38 9.45 0.46 5.42e-19 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs6426558 0.537 rs6662583 chr1:227383889 A/G cg10327440 chr1:227177885 CDC42BPA -0.49 -7.98 -0.4 2.19e-14 Neutrophil percentage of white cells; LIHC cis rs9612 0.948 rs189408 chr19:44268006 T/C cg08581076 chr19:44259116 C19orf61 0.62 7.55 0.38 3.9e-13 Exhaled nitric oxide output; LIHC cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg09904177 chr6:26538194 HMGN4 0.56 11.01 0.51 2.4e-24 Intelligence (multi-trait analysis); LIHC cis rs6120849 0.754 rs6120812 chr20:33629427 T/C cg24642439 chr20:33292090 TP53INP2 0.65 7.05 0.36 9.65e-12 Protein C levels; LIHC cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.67 0.57 1.98e-30 Total body bone mineral density; LIHC cis rs7772486 0.875 rs864390 chr6:146315035 G/T cg23711669 chr6:146136114 FBXO30 0.59 10.29 0.49 8.02e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg10802521 chr3:52805072 NEK4 -0.43 -6.9 -0.35 2.55e-11 Bipolar disorder; LIHC trans rs875971 0.964 rs6978721 chr7:65883204 A/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs10193935 0.901 rs72800020 chr2:42655615 A/G cg27598129 chr2:42591480 NA -0.69 -10.05 -0.48 5.55e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs9733 0.566 rs112967224 chr1:150677263 G/A cg18016565 chr1:150552671 MCL1 0.58 11.5 0.53 4.36e-26 Tonsillectomy; LIHC cis rs1799949 0.827 rs74252763 chr17:41402020 C/T cg23758822 chr17:41437982 NA 0.95 17.06 0.68 1.18e-47 Menopause (age at onset); LIHC cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs10916814 1.000 rs12145310 chr1:20901064 C/A cg24502330 chr1:20914028 CDA -0.28 -5.91 -0.3 8.28e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10416265 0.527 rs6510337 chr19:33545701 C/T cg27124370 chr19:33622961 WDR88 0.56 7.95 0.4 2.67e-14 Bone properties (heel); LIHC cis rs72781680 1.000 rs17762102 chr2:24085606 A/G cg08917208 chr2:24149416 ATAD2B 0.86 8.17 0.4 5.99e-15 Lymphocyte counts; LIHC cis rs1371867 0.846 rs1660338 chr8:101242757 C/G cg06636551 chr8:101224915 SPAG1 -0.47 -9.27 -0.45 2.19e-18 Atrioventricular conduction; LIHC cis rs2573652 1.000 rs2573650 chr15:100514097 A/G cg09918751 chr15:100517450 ADAMTS17 0.77 13.49 0.59 1.51e-33 Height; LIHC trans rs1814175 0.615 rs11040654 chr11:49939485 T/G cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC cis rs11690935 0.959 rs75922913 chr2:172620152 T/C cg13550731 chr2:172543902 DYNC1I2 -0.94 -17.68 -0.69 3.78e-50 Schizophrenia; LIHC cis rs2576037 0.562 rs612519 chr18:44379490 G/A cg19077165 chr18:44547161 KATNAL2 -0.46 -6.84 -0.35 3.65e-11 Personality dimensions; LIHC cis rs3617 0.591 rs2276823 chr3:52869263 C/A cg11645453 chr3:52864694 ITIH4 -0.21 -5.82 -0.3 1.33e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.17 -0.32 1.88e-9 Total body bone mineral density; LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.818 rs12498599 chr4:120468503 C/T cg09307838 chr4:120376055 NA 0.76 11.71 0.54 7.22e-27 Corneal astigmatism; LIHC cis rs17685 0.593 rs56265719 chr7:75796269 C/T cg01364799 chr7:75623366 TMEM120A -0.43 -6.44 -0.33 4.14e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7089973 0.604 rs11196943 chr10:116598865 T/C cg23260525 chr10:116636907 FAM160B1 0.35 7.05 0.36 1.02e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg13395646 chr4:1353034 KIAA1530 -0.5 -8.3 -0.41 2.51e-15 Obesity-related traits; LIHC cis rs7116495 1.000 rs7121260 chr11:71700566 C/T cg26138937 chr11:71823887 C11orf51 -0.75 -7.44 -0.37 8.04e-13 Severe influenza A (H1N1) infection; LIHC cis rs1552244 0.554 rs6800204 chr3:9995404 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.57 8.1 0.4 1.01e-14 Alzheimer's disease; LIHC cis rs7107174 1.000 rs10899468 chr11:78016650 C/T cg02023728 chr11:77925099 USP35 0.5 9.5 0.46 3.65e-19 Testicular germ cell tumor; LIHC cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg27286337 chr10:134555280 INPP5A 0.87 12.52 0.56 7.35e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10256972 0.647 rs10233430 chr7:1051664 T/C cg04025307 chr7:1156635 C7orf50 0.38 6.02 0.31 4.42e-9 Longevity;Endometriosis; LIHC cis rs9811920 0.609 rs4928232 chr3:99694217 G/A cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.78 -0.3 1.64e-8 Axial length; LIHC cis rs860626 0.512 rs2786198 chr10:119313196 A/G cg10846980 chr10:119306025 EMX2;EMX2OS -0.53 -8.21 -0.41 4.6e-15 Neuroticism; LIHC cis rs3736485 0.934 rs8036904 chr15:51861438 G/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1005277 0.602 rs2504142 chr10:38383793 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg15691649 chr6:25882328 NA 0.57 7.41 0.37 1.02e-12 Intelligence (multi-trait analysis); LIHC cis rs4975616 0.836 rs421629 chr5:1320136 G/A cg07493874 chr5:1342172 CLPTM1L -0.66 -10.26 -0.49 1e-21 Lung cancer; LIHC cis rs3812831 0.662 rs418027 chr13:114929344 A/C cg08824895 chr13:115047677 UPF3A 0.42 6.07 0.31 3.34e-9 Schizophrenia; LIHC trans rs2243480 0.901 rs778732 chr7:65822360 C/T cg10756647 chr7:56101905 PSPH 1.03 12.52 0.56 7.08e-30 Diabetic kidney disease; LIHC cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg02931644 chr1:25747376 RHCE 0.35 7.58 0.38 3.37e-13 Plateletcrit;Mean corpuscular volume; LIHC cis rs7716219 0.524 rs57997842 chr5:54869982 G/T cg14753740 chr5:54468940 CDC20B;MIR449C 0.44 6.19 0.32 1.77e-9 Height; LIHC cis rs16828019 0.852 rs16827876 chr1:41539536 T/G cg03962019 chr1:41807865 NA 0.5 7.32 0.37 1.73e-12 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg03806693 chr22:41940476 POLR3H -0.91 -10.6 -0.5 7.01e-23 Vitiligo; LIHC cis rs9393777 0.513 rs13190754 chr6:26587406 G/A cg12826209 chr6:26865740 GUSBL1 0.56 6.37 0.33 6.26e-10 Intelligence (multi-trait analysis); LIHC trans rs72960926 0.744 rs72952273 chr6:74926284 C/T cg07247405 chr1:2484626 LOC115110 0.55 6.61 0.34 1.44e-10 Metabolite levels (MHPG); LIHC cis rs2637266 0.783 rs846634 chr10:78535323 C/A cg18941641 chr10:78392320 NA 0.28 5.96 0.31 6.12e-9 Pulmonary function; LIHC cis rs10464366 0.544 rs4540324 chr7:39185299 G/C cg10621924 chr7:39171070 POU6F2 0.41 6.45 0.33 3.86e-10 IgG glycosylation; LIHC cis rs7937682 0.889 rs564086 chr11:111501079 C/G cg09085632 chr11:111637200 PPP2R1B -1.03 -12.24 -0.55 7.9e-29 Primary sclerosing cholangitis; LIHC cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg27535305 chr1:53392650 SCP2 0.32 6.32 0.32 8.31e-10 Monocyte count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13108601 chr6:41748242 FRS3;PRICKLE4 0.38 6.09 0.31 3.09e-9 Cognitive function; LIHC cis rs6570726 0.791 rs4332001 chr6:145934841 T/C cg23711669 chr6:146136114 FBXO30 0.62 10.58 0.5 8.03e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs317689 0.819 rs317683 chr12:69713630 T/G cg20891283 chr12:69753455 YEATS4 0.58 8.76 0.43 9.34e-17 Response to diuretic therapy; LIHC cis rs9303401 0.659 rs12150264 chr17:56939927 G/A cg25039879 chr17:56429692 SUPT4H1 0.8 9.04 0.44 1.18e-17 Cognitive test performance; LIHC cis rs7089973 0.604 rs7903663 chr10:116609904 G/A cg23260525 chr10:116636907 FAM160B1 0.36 7.07 0.36 8.97e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs17290760 1.000 rs17289655 chr9:32486507 A/G cg22609511 chr7:28891164 NA 0.61 6.39 0.33 5.57e-10 Immune response to smallpox vaccine (IL-6); LIHC cis rs4665809 0.652 rs6727974 chr2:26524639 A/G cg26119090 chr2:26468346 HADHA;HADHB 0.95 14.74 0.62 2.1e-38 Gut microbiome composition (summer); LIHC cis rs1564271 0.961 rs2927921 chr10:27016001 A/C cg13837822 chr10:26931731 LOC731789 0.33 5.85 0.3 1.13e-8 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg10755058 chr3:40428713 ENTPD3 0.4 6.94 0.35 2.02e-11 Renal cell carcinoma; LIHC cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg18404041 chr3:52824283 ITIH1 -0.58 -9.58 -0.46 2.06e-19 Bipolar disorder; LIHC cis rs1144333 0.522 rs1144338 chr1:76279908 T/C cg03433033 chr1:76189801 ACADM -0.45 -7.08 -0.36 8.2e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs4819052 0.851 rs35064782 chr21:46674360 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.69 10.67 0.5 4.05e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10276381 1.000 rs7796417 chr7:28186119 G/C cg23620719 chr7:28220237 JAZF1 0.62 7.7 0.38 1.51e-13 Crohn's disease; LIHC cis rs9513627 1.000 rs6491511 chr13:100198717 C/A cg25919922 chr13:100150906 NA 0.77 6.89 0.35 2.62e-11 Obesity-related traits; LIHC cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg08499158 chr17:42289980 UBTF 0.52 8.54 0.42 4.64e-16 Total body bone mineral density; LIHC cis rs60871478 0.636 rs55663559 chr7:884057 G/A cg05535760 chr7:792225 HEATR2 -0.8 -6.29 -0.32 9.77e-10 Cerebrospinal P-tau181p levels; LIHC cis rs7523273 0.606 rs2796283 chr1:207978732 C/T cg22525895 chr1:207977042 MIR29B2 -0.61 -9.91 -0.47 1.67e-20 Schizophrenia; LIHC cis rs11758351 0.660 rs1997768 chr6:26217728 C/T cg03854865 chr6:26224070 HIST1H3E -0.58 -6.62 -0.34 1.37e-10 Gout;Renal underexcretion gout; LIHC trans rs6580110 0.714 rs9324791 chr5:154078556 T/C cg02272667 chr7:1922866 MAD1L1 0.29 6.05 0.31 3.72e-9 Facial morphology (factor 9, facial height related to vertical position of nasion); LIHC cis rs2180341 0.842 rs9375492 chr6:127545492 C/T cg27446573 chr6:127587934 RNF146 -1.0 -14.26 -0.61 1.6e-36 Breast cancer; LIHC trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg01171360 chr6:293285 DUSP22 -0.41 -6.13 -0.31 2.38e-9 Menopause (age at onset); LIHC cis rs9942416 0.533 rs4704235 chr5:75024380 A/C cg19683494 chr5:74908142 NA 0.57 6.17 0.32 1.97e-9 Age-related disease endophenotypes; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg10577273 chr11:64595102 CDC42BPG 0.42 6.21 0.32 1.55e-9 Longevity; LIHC cis rs2204008 0.805 rs11169513 chr12:37988640 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.68 0.5 3.64e-23 Bladder cancer; LIHC cis rs9905704 0.671 rs4337355 chr17:56950920 C/T cg12560992 chr17:57184187 TRIM37 0.68 9.94 0.47 1.24e-20 Testicular germ cell tumor; LIHC trans rs11039100 0.920 rs12792905 chr11:5821544 G/C cg11650987 chr12:10280440 CLEC7A 0.4 6.05 0.31 3.73e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1499280 0.790 rs7719925 chr5:52105306 T/G cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg27170947 chr2:26402098 FAM59B -0.7 -8.55 -0.42 4.24e-16 Gut microbiome composition (summer); LIHC cis rs7605378 0.528 rs1704191 chr2:200816393 C/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.51 6.51 0.33 2.73e-10 Osteoporosis; LIHC cis rs6598955 0.670 rs3795688 chr1:26560481 C/A cg04990556 chr1:26633338 UBXN11 -0.62 -10.32 -0.49 6.59e-22 Obesity-related traits; LIHC cis rs57784326 1 rs57784326 chr15:49796630 A/AG cg04482760 chr15:49339272 SECISBP2L 0.42 6.28 0.32 1e-9 Bacterial meningitis; LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.15 0.55 1.79e-28 Prudent dietary pattern; LIHC cis rs1728785 0.892 rs9928950 chr16:68557114 G/A cg02972257 chr16:68554789 NA 0.58 6.12 0.31 2.51e-9 Ulcerative colitis; LIHC trans rs4824093 0.610 rs74371371 chr22:50314074 C/T cg09872104 chr7:134855509 C7orf49 -0.76 -6.19 -0.32 1.68e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg04267008 chr7:1944627 MAD1L1 -0.6 -9.3 -0.45 1.67e-18 Bipolar disorder and schizophrenia; LIHC cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg09455208 chr3:40491958 NA -0.34 -6.98 -0.35 1.52e-11 Renal cell carcinoma; LIHC cis rs7944584 0.837 rs11039149 chr11:47276675 A/G cg20307385 chr11:47447363 PSMC3 0.64 6.57 0.33 1.9e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs1577917 1.000 rs7756203 chr6:86627707 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC cis rs2979489 0.786 rs2979514 chr8:30399461 A/C cg26383811 chr8:30366931 RBPMS -0.71 -11.86 -0.54 2.11e-27 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs4665809 1.000 rs4665304 chr2:26313406 C/T cg04944784 chr2:26401820 FAM59B -0.65 -8.26 -0.41 3.25e-15 Gut microbiome composition (summer); LIHC cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg15691649 chr6:25882328 NA -0.9 -11.99 -0.54 6.73e-28 Intelligence (multi-trait analysis); LIHC cis rs7937890 0.572 rs2597202 chr11:14484645 C/T cg02886208 chr11:14281011 SPON1 -0.5 -6.74 -0.34 6.69e-11 Mitochondrial DNA levels; LIHC cis rs3768617 0.510 rs2333621 chr1:183090751 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg08888203 chr3:10149979 C3orf24 0.44 5.79 0.3 1.57e-8 Alzheimer's disease; LIHC cis rs807029 0.577 rs3740489 chr10:102754238 A/G cg17130504 chr10:102756923 LZTS2 0.55 7.55 0.38 3.92e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs1559088 0.576 rs11084707 chr19:33612873 C/T cg27124370 chr19:33622961 WDR88 0.59 8.81 0.43 6.49e-17 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs17102423 0.760 rs2781375 chr14:65569597 A/G cg16583315 chr14:65563665 MAX -0.42 -8.57 -0.42 3.63e-16 Obesity-related traits; LIHC cis rs10256972 0.706 rs12701969 chr7:1121849 A/G cg07092213 chr7:1199455 ZFAND2A -0.43 -6.39 -0.33 5.47e-10 Longevity;Endometriosis; LIHC cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.25 -0.45 2.47e-18 Intelligence (multi-trait analysis); LIHC cis rs924607 0.966 rs1621827 chr5:635074 A/G cg24163568 chr5:669837 TPPP 0.39 8.14 0.4 7.4e-15 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1008375 1.000 rs10939738 chr4:17604295 G/C cg16339924 chr4:17578868 LAP3 0.41 5.73 0.3 2.25e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2932538 0.883 rs6537740 chr1:113080084 T/G cg22162597 chr1:113214053 CAPZA1 0.69 9.33 0.45 1.36e-18 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs7618501 1.000 rs3749241 chr3:49744392 A/G cg21659725 chr3:3221576 CRBN -0.99 -19.35 -0.72 7.4e-57 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs727505 1.000 rs7801661 chr7:124483222 C/T cg23710748 chr7:124431027 NA 0.34 6.16 0.32 2.07e-9 Lewy body disease; LIHC cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg13047869 chr3:10149882 C3orf24 0.52 6.31 0.32 8.85e-10 Alzheimer's disease; LIHC cis rs7131987 1.000 rs7131987 chr12:29406488 G/T cg21522988 chr12:29376872 FAR2 0.29 6.69 0.34 9.39e-11 QT interval; LIHC cis rs7534824 0.625 rs61780284 chr1:101355166 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 6.77 0.34 5.7e-11 Refractive astigmatism; LIHC cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg04944784 chr2:26401820 FAM59B -0.77 -9.49 -0.46 4.14e-19 Gut microbiome composition (summer); LIHC cis rs12478296 1.000 rs56136197 chr2:243043877 T/C cg18898632 chr2:242989856 NA -0.58 -7.81 -0.39 6.93e-14 Obesity-related traits; LIHC cis rs1371867 0.764 rs1020171 chr8:101288610 T/C cg06636551 chr8:101224915 SPAG1 -0.5 -9.05 -0.44 1.13e-17 Atrioventricular conduction; LIHC cis rs9640161 0.636 rs3735171 chr7:150033882 A/G cg27494647 chr7:150038898 RARRES2 0.34 6.23 0.32 1.4e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs760805 0.932 rs1005734 chr1:25262022 C/A cg22509179 chr1:25234806 RUNX3 -0.39 -8.16 -0.4 6.3e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs12431939 1.000 rs55851845 chr14:51645583 A/T cg23942311 chr14:51606299 NA -0.36 -6.07 -0.31 3.48e-9 Cancer; LIHC cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg20887711 chr4:1340912 KIAA1530 -0.71 -10.85 -0.51 8.93e-24 Obesity-related traits; LIHC cis rs17102423 1.000 rs4902365 chr14:65602064 T/C cg11161011 chr14:65562177 MAX -0.42 -5.72 -0.3 2.33e-8 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14589014 chr11:2952043 PHLDA2 0.46 6.48 0.33 3.26e-10 Lung function (FEV1/FVC); LIHC cis rs882732 0.744 rs11847476 chr14:95047605 G/T cg14866387 chr14:95027382 SERPINA4 -0.49 -6.44 -0.33 4.08e-10 Blood protein levels; LIHC cis rs8053891 0.615 rs2000999 chr16:72108093 G/A cg01557791 chr16:72042693 DHODH -0.45 -6.13 -0.31 2.44e-9 Coronary artery disease; LIHC cis rs769267 0.930 rs2315022 chr19:19413381 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.61 9.57 0.46 2.3e-19 Tonsillectomy; LIHC cis rs6912958 0.712 rs6454640 chr6:88370352 G/T cg08069147 chr6:88032118 GJB7;C6orf162 0.45 7.96 0.4 2.55e-14 Monocyte percentage of white cells; LIHC cis rs6860806 0.507 rs2631364 chr5:131706914 C/G cg24060327 chr5:131705240 SLC22A5 0.8 12.7 0.57 1.49e-30 Breast cancer; LIHC cis rs6502050 0.835 rs67106357 chr17:80116826 T/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.68e-9 Life satisfaction; LIHC cis rs875971 0.571 rs160641 chr7:65577346 G/A cg11764359 chr7:65958608 NA -0.5 -6.76 -0.34 5.85e-11 Aortic root size; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg08888203 chr3:10149979 C3orf24 0.61 6.96 0.35 1.78e-11 Alzheimer's disease; LIHC cis rs7607369 0.791 rs72965151 chr2:219344165 G/T cg02176678 chr2:219576539 TTLL4 -0.57 -7.95 -0.4 2.71e-14 Red blood cell count;Amyotrophic lateral sclerosis; LIHC trans rs12155400 0.661 rs1030557 chr7:18346636 A/G cg18816595 chr3:42750454 CCDC13 0.4 6.27 0.32 1.11e-9 Retinopathy in non-diabetics; LIHC cis rs7572733 0.534 rs7557203 chr2:198795650 A/G cg10820045 chr2:198174542 NA 0.48 7.43 0.37 8.73e-13 Dermatomyositis; LIHC trans rs1493916 0.807 rs10775455 chr18:31310761 A/C cg27147174 chr7:100797783 AP1S1 -0.45 -6.94 -0.35 1.93e-11 Life satisfaction; LIHC cis rs2732480 0.517 rs2634676 chr12:48738236 A/G cg21466736 chr12:48725269 NA -0.72 -10.85 -0.51 8.84e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs769267 0.895 rs2916073 chr19:19528324 T/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.87 0.3 1.02e-8 Tonsillectomy; LIHC cis rs2282802 0.660 rs7726176 chr5:139547971 T/A cg26211634 chr5:139558579 C5orf32 -0.38 -5.85 -0.3 1.13e-8 Intelligence (multi-trait analysis); LIHC cis rs6429082 0.521 rs704711 chr1:235629802 G/A cg26050004 chr1:235667680 B3GALNT2 0.82 14.51 0.62 1.67e-37 Adiposity; LIHC cis rs12497850 0.829 rs8926 chr3:49052785 T/A cg07636037 chr3:49044803 WDR6 0.93 17.21 0.68 3.03e-48 Parkinson's disease; LIHC cis rs12579753 0.872 rs34415838 chr12:82122078 T/C cg07988820 chr12:82153109 PPFIA2 -0.5 -6.23 -0.32 1.33e-9 Resting heart rate; LIHC cis rs2629540 0.765 rs4962687 chr10:126404141 G/A cg08799069 chr10:126477246 METTL10 -0.36 -5.89 -0.3 9.35e-9 Cocaine dependence; LIHC cis rs3749237 0.595 rs4855873 chr3:49459114 A/C cg06212747 chr3:49208901 KLHDC8B 0.44 5.84 0.3 1.21e-8 Resting heart rate; LIHC cis rs1506636 1.000 rs614645 chr7:123442349 T/C cg03229431 chr7:123269106 ASB15 0.51 8.28 0.41 2.82e-15 Plateletcrit;Platelet count; LIHC cis rs9300255 0.507 rs1615350 chr12:123650335 C/T cg00376283 chr12:123451042 ABCB9 0.75 12.24 0.55 8.04e-29 Neutrophil percentage of white cells; LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg08280861 chr8:58055591 NA 0.5 6.18 0.32 1.78e-9 Developmental language disorder (linguistic errors); LIHC cis rs7129220 0.588 rs7124925 chr11:10143700 G/A cg01453529 chr11:10209919 SBF2 -0.38 -6.71 -0.34 8.23e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs1023500 0.551 rs2859438 chr22:42466980 A/T cg15557168 chr22:42548783 NA -0.44 -6.93 -0.35 2.06e-11 Schizophrenia; LIHC cis rs5769765 0.908 rs9616396 chr22:50317825 T/C cg26441486 chr22:50317300 CRELD2 0.37 6.31 0.32 8.89e-10 Schizophrenia; LIHC cis rs3741151 1.000 rs74346863 chr11:73054772 C/T cg17517138 chr11:73019481 ARHGEF17 0.9 6.61 0.34 1.52e-10 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs6120849 0.754 rs3746435 chr20:33587198 G/C cg24642439 chr20:33292090 TP53INP2 0.66 7.3 0.37 2.08e-12 Protein C levels; LIHC cis rs12477438 0.520 rs11692699 chr2:99730657 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.54 0.77 1.37e-69 Chronic sinus infection; LIHC cis rs3008870 1.000 rs11208979 chr1:67442275 C/T cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs765787 0.530 rs2554454 chr15:45521536 A/G cg24006582 chr15:45444508 DUOX1 -0.51 -7.31 -0.37 1.96e-12 Uric acid levels; LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg26338869 chr17:61819248 STRADA 0.6 8.46 0.42 8.12e-16 Prudent dietary pattern; LIHC cis rs765787 0.530 rs2413784 chr15:45530516 A/C cg25801113 chr15:45476975 SHF 0.36 6.15 0.32 2.22e-9 Uric acid levels; LIHC cis rs9309473 1.000 rs11901272 chr2:73720444 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.84 -0.35 3.68e-11 Metabolite levels; LIHC cis rs4474465 1.000 rs10899502 chr11:78141021 C/T cg27205649 chr11:78285834 NARS2 -0.41 -6.22 -0.32 1.42e-9 Alzheimer's disease (survival time); LIHC cis rs7408868 0.831 rs7245850 chr19:15274585 A/C cg14696996 chr19:15285081 NOTCH3 0.53 7.02 0.35 1.2e-11 Pulse pressure; LIHC cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg00750074 chr16:89608354 SPG7 -0.5 -8.14 -0.4 7.3e-15 Multiple myeloma (IgH translocation); LIHC cis rs244293 0.730 rs11079142 chr17:53021955 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.01 -0.31 4.83e-9 Menarche (age at onset); LIHC cis rs1005277 0.522 rs7072977 chr10:37940440 C/A cg00409905 chr10:38381863 ZNF37A -0.55 -9.53 -0.46 2.98e-19 Extrinsic epigenetic age acceleration; LIHC cis rs9733 0.596 rs1415148 chr1:150705755 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs9425766 0.640 rs2281486 chr1:173822221 A/G cg06124660 chr1:173389066 NA -0.33 -6.4 -0.33 5.25e-10 Life satisfaction; LIHC cis rs3736485 0.932 rs2124879 chr15:51916833 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.14 -0.32 2.23e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9902453 0.619 rs2244585 chr17:28072176 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -12.72 -0.57 1.27e-30 Coffee consumption (cups per day); LIHC cis rs3099143 0.901 rs3764244 chr15:77223740 T/C cg21673338 chr15:77095150 SCAPER -0.49 -7.07 -0.36 8.97e-12 Recalcitrant atopic dermatitis; LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg10150615 chr22:24372951 LOC391322 0.49 6.77 0.34 5.52e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs208520 1.000 rs12209225 chr6:66996443 G/T cg07460842 chr6:66804631 NA 0.68 7.38 0.37 1.22e-12 Exhaled nitric oxide output; LIHC cis rs9325144 0.647 rs7980932 chr12:38921583 G/T cg26384229 chr12:38710491 ALG10B -0.49 -7.0 -0.35 1.36e-11 Morning vs. evening chronotype; LIHC cis rs1008375 0.897 rs3733577 chr4:17649233 T/G cg02297831 chr4:17616191 MED28 0.48 7.55 0.38 4.04e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7216064 0.700 rs4791295 chr17:65997317 G/A cg12091567 chr17:66097778 LOC651250 -0.75 -11.24 -0.52 3.6e-25 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg11890956 chr21:40555474 PSMG1 -0.51 -8.18 -0.4 5.64e-15 Cognitive function; LIHC cis rs548181 0.736 rs556884 chr11:125550049 G/A cg03464685 chr11:125439445 EI24 0.92 10.0 0.48 7.97e-21 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3736594 0.546 rs6734059 chr2:27808154 C/T cg27432699 chr2:27873401 GPN1 -0.46 -6.92 -0.35 2.27e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2795502 1.000 rs2744092 chr10:43339343 T/C cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs644799 0.540 rs10831422 chr11:95478968 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.56 7.05 0.36 1.01e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6714710 0.603 rs4311104 chr2:98424802 A/G cg26665480 chr2:98280029 ACTR1B 0.43 6.11 0.31 2.71e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27309920 chr12:6798957 ZNF384 0.45 7.36 0.37 1.35e-12 Cognitive function; LIHC trans rs1842329 0.813 rs1480071 chr12:98564904 A/G cg14298269 chr14:102689372 WDR20 0.38 6.13 0.31 2.47e-9 Bipolar disorder; LIHC cis rs6088580 0.634 rs6059856 chr20:33057954 G/C cg08999081 chr20:33150536 PIGU 0.67 13.39 0.59 3.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs1008375 0.932 rs2302394 chr4:17641188 A/G cg02297831 chr4:17616191 MED28 0.42 6.0 0.31 5.16e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2153535 0.580 rs9379215 chr6:8481225 G/A cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs1506636 0.962 rs10273985 chr7:123309538 A/T cg03229431 chr7:123269106 ASB15 -0.6 -12.22 -0.55 9.85e-29 Plateletcrit;Platelet count; LIHC cis rs1023500 0.573 rs8135801 chr22:42475568 A/G cg15557168 chr22:42548783 NA 0.42 6.66 0.34 1.12e-10 Schizophrenia; LIHC cis rs3770081 0.826 rs1019591 chr2:86298599 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.86 -8.52 -0.42 5.12e-16 Facial emotion recognition (sad faces); LIHC cis rs798554 0.757 rs1182187 chr7:2870454 T/G cg04166393 chr7:2884313 GNA12 0.44 5.86 0.3 1.07e-8 Height; LIHC cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3796352 1.000 rs34313969 chr3:52995166 A/G cg04865290 chr3:52927548 TMEM110 -0.51 -5.9 -0.3 8.82e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs3764618 1.000 rs3764617 chr19:49497123 T/C cg14640682 chr19:49496473 GYS1;RUVBL2 -0.73 -5.95 -0.31 6.8e-9 Follicule stimulating hormone; LIHC cis rs1707322 1.000 rs6677777 chr1:46475836 A/G cg03146154 chr1:46216737 IPP 0.49 7.62 0.38 2.45e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs864643 1.000 rs1340222 chr3:39549803 C/T cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs909341 1.000 rs909341 chr20:62328742 C/T cg03999872 chr20:62272968 STMN3 -0.46 -6.81 -0.35 4.44e-11 Atopic dermatitis; LIHC cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg16680214 chr1:154839983 KCNN3 -0.35 -5.86 -0.3 1.08e-8 Prostate cancer; LIHC cis rs911119 1.000 rs734801 chr20:23612791 A/G cg16589663 chr20:23618590 CST3 0.74 7.76 0.39 1e-13 Chronic kidney disease; LIHC cis rs1816752 1.000 rs9511265 chr13:25012359 T/C cg22771759 chr13:24902376 NA 0.33 6.89 0.35 2.66e-11 Obesity-related traits; LIHC cis rs875971 0.965 rs10267430 chr7:65743023 G/T cg18252515 chr7:66147081 NA 0.42 6.03 0.31 4.17e-9 Aortic root size; LIHC cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg21280719 chr6:42927975 GNMT -0.33 -7.22 -0.36 3.42e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3820068 0.581 rs1547031 chr1:15918960 G/A cg17385448 chr1:15911702 AGMAT 0.35 5.94 0.31 7.07e-9 Systolic blood pressure; LIHC cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg03264133 chr6:25882463 NA 0.9 12.2 0.55 1.15e-28 Blood metabolite levels; LIHC cis rs1005277 0.579 rs2474587 chr10:38420666 C/T cg00409905 chr10:38381863 ZNF37A -0.62 -10.86 -0.51 8.71e-24 Extrinsic epigenetic age acceleration; LIHC cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.95 -10.38 -0.49 4.15e-22 Platelet count; LIHC cis rs9733 0.818 rs4970924 chr1:150633079 A/G cg13175981 chr1:150552382 MCL1 0.51 7.95 0.39 2.74e-14 Tonsillectomy; LIHC cis rs3806843 0.735 rs702394 chr5:140086786 A/G cg16179182 chr5:140090404 VTRNA1-1 0.36 5.9 0.3 8.66e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs74417235 0.639 rs2396994 chr5:154052750 A/T cg08754654 chr5:154026448 NA -0.33 -7.26 -0.37 2.61e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg26338869 chr17:61819248 STRADA 0.51 6.76 0.34 5.95e-11 Height; LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg05185784 chr16:90016020 DEF8 -0.48 -6.18 -0.32 1.84e-9 Skin colour saturation; LIHC trans rs61931739 0.534 rs1608911 chr12:34010249 T/C cg26384229 chr12:38710491 ALG10B 0.51 7.14 0.36 5.65e-12 Morning vs. evening chronotype; LIHC cis rs769267 0.792 rs4808961 chr19:19577215 C/G cg03709012 chr19:19516395 GATAD2A 1.0 17.55 0.69 1.29e-49 Tonsillectomy; LIHC trans rs1814175 0.746 rs10839429 chr11:49906845 G/A cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs490234 0.676 rs12202 chr9:128200299 C/G cg14078157 chr9:128172775 NA -0.39 -6.6 -0.34 1.61e-10 Mean arterial pressure; LIHC trans rs9747201 0.962 rs11656153 chr17:80072950 G/A cg07393940 chr7:158741817 NA -0.57 -6.75 -0.34 6.18e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs8141529 0.600 rs916332 chr22:29308414 C/T cg15103426 chr22:29168792 CCDC117 0.44 6.07 0.31 3.41e-9 Lymphocyte counts; LIHC trans rs4699052 0.537 rs1580278 chr4:104140848 A/C cg16471864 chr4:38666270 KLF3;FLJ13197 0.43 6.09 0.31 3e-9 Testicular germ cell tumor; LIHC trans rs1005277 0.505 rs13503 chr10:38239843 C/A cg17830980 chr10:43048298 ZNF37B 0.46 8.96 0.44 2.13e-17 Extrinsic epigenetic age acceleration; LIHC cis rs7258465 1.000 rs7258465 chr19:18533642 A/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.38 -0.37 1.22e-12 Breast cancer; LIHC cis rs6748734 0.948 rs9973334 chr2:241838142 A/G cg08694578 chr2:241835147 C2orf54 -0.63 -10.17 -0.48 2.19e-21 Urinary metabolites; LIHC cis rs11676348 0.818 rs4674256 chr2:218987893 A/T cg00012203 chr2:219082015 ARPC2 -0.55 -7.8 -0.39 7.5e-14 Ulcerative colitis; LIHC cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg11764359 chr7:65958608 NA -0.68 -9.28 -0.45 2.01e-18 Aortic root size; LIHC cis rs2710642 0.751 rs10496099 chr2:62805902 T/C cg17519650 chr2:63277830 OTX1 0.43 6.21 0.32 1.54e-9 LDL cholesterol levels;LDL cholesterol; LIHC cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.913 rs7106339 chr11:68240241 C/T cg16797656 chr11:68205561 LRP5 0.54 8.52 0.42 5.02e-16 Total body bone mineral density; LIHC trans rs12478296 1.000 rs6732595 chr2:243035338 T/C cg01596870 chr19:55963115 NA -0.64 -8.58 -0.42 3.33e-16 Obesity-related traits; LIHC cis rs9715521 0.677 rs62301200 chr4:59855179 G/A cg11281224 chr4:60001000 NA -0.33 -6.34 -0.32 7.21e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs11039798 0.920 rs11040013 chr11:48782862 G/A cg15704280 chr7:45808275 SEPT13 0.63 6.57 0.33 1.82e-10 Axial length; LIHC cis rs7605378 0.658 rs4673507 chr2:200710167 G/C cg17644776 chr2:200775616 C2orf69 0.4 6.08 0.31 3.19e-9 Osteoporosis; LIHC cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg12463550 chr7:65579703 CRCP -0.69 -7.22 -0.36 3.41e-12 Diabetic kidney disease; LIHC cis rs929354 0.742 rs11980541 chr7:156988776 G/C cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs3751667 0.506 rs4984718 chr16:974411 T/A cg07002422 chr16:996172 LMF1 -0.39 -6.53 -0.33 2.44e-10 Non-glioblastoma glioma;Glioblastoma;Glioma; LIHC cis rs9443189 0.806 rs9359139 chr6:76487269 C/G cg01950844 chr6:76311363 SENP6 0.48 5.79 0.3 1.56e-8 Prostate cancer; LIHC cis rs4555082 0.789 rs2816649 chr14:105708326 A/G cg10792982 chr14:105748885 BRF1 0.42 5.92 0.31 7.7e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg07133347 chr1:107600762 PRMT6 0.45 6.77 0.34 5.67e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg04025307 chr7:1156635 C7orf50 0.59 10.36 0.49 4.57e-22 Longevity;Endometriosis; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg05114486 chr19:875279 MED16 0.39 6.09 0.31 3.01e-9 Alopecia areata; LIHC cis rs9790314 0.730 rs4856705 chr3:161100219 T/G cg03342759 chr3:160939853 NMD3 -0.48 -7.09 -0.36 7.89e-12 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg24209194 chr3:40518798 ZNF619 0.63 9.71 0.46 7.86e-20 Renal cell carcinoma; LIHC cis rs77633900 0.614 rs203753 chr15:76946195 A/T cg21673338 chr15:77095150 SCAPER -0.5 -7.39 -0.37 1.11e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs7582180 0.629 rs36103184 chr2:100942634 G/A cg14675211 chr2:100938903 LONRF2 0.53 8.29 0.41 2.55e-15 Intelligence (multi-trait analysis); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg09563731 chr19:4090587 MAP2K2 0.44 6.37 0.33 6.03e-10 Bilirubin levels; LIHC cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg12386194 chr3:101231763 SENP7 0.47 6.86 0.35 3.32e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs10193935 0.901 rs10169411 chr2:42637749 G/A cg27598129 chr2:42591480 NA -0.71 -11.18 -0.52 6.24e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs11608355 0.545 rs12822891 chr12:109896002 A/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC trans rs1005277 0.579 rs1740737 chr10:38499365 G/T cg17830980 chr10:43048298 ZNF37B -0.52 -10.07 -0.48 4.6e-21 Extrinsic epigenetic age acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04362369 chr14:21905501 CHD8 -0.42 -6.15 -0.32 2.19e-9 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15159625 chr1:118042759 MAN1A2 0.3 6.25 0.32 1.22e-9 Cognitive function; LIHC cis rs2075371 1.000 rs2598285 chr7:133971153 A/T cg20476274 chr7:133979776 SLC35B4 0.77 13.31 0.58 7.55e-33 Mean platelet volume; LIHC cis rs6952808 0.500 rs3800902 chr7:2144378 C/T cg20295408 chr7:1910781 MAD1L1 -0.41 -6.02 -0.31 4.51e-9 Bipolar disorder and schizophrenia; LIHC cis rs506338 0.517 rs530775 chr11:64426933 A/G cg03263716 chr11:64435066 NRXN2 0.34 7.38 0.37 1.22e-12 Body mass index;Urate levels; LIHC cis rs1552244 0.572 rs12107622 chr3:10171898 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 8.9 0.43 3.43e-17 Alzheimer's disease; LIHC cis rs2404602 0.647 rs3812908 chr15:77176158 C/T cg03037974 chr15:76606532 NA 0.61 10.43 0.49 2.6e-22 Blood metabolite levels; LIHC cis rs2404602 0.575 rs11633309 chr15:76962349 C/A cg23625390 chr15:77176239 SCAPER -0.47 -7.41 -0.37 9.94e-13 Blood metabolite levels; LIHC trans rs61931739 0.534 rs7302688 chr12:34235064 A/G cg26384229 chr12:38710491 ALG10B 0.57 7.38 0.37 1.2e-12 Morning vs. evening chronotype; LIHC cis rs12477438 1.000 rs12477438 chr2:99841085 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.72 -9.29 -0.45 1.84e-18 Chronic sinus infection; LIHC cis rs6089584 0.888 rs2386555 chr20:60612373 C/T cg13770153 chr20:60521292 NA -0.34 -6.81 -0.35 4.38e-11 Body mass index; LIHC cis rs1215050 0.791 rs260889 chr4:98742340 A/G cg05340658 chr4:99064831 C4orf37 0.38 5.76 0.3 1.84e-8 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs11098499 0.909 rs28668716 chr4:120309875 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.67 0.42 1.74e-16 Corneal astigmatism; LIHC cis rs1707322 0.752 rs28550303 chr1:46188914 G/T cg06784218 chr1:46089804 CCDC17 0.41 7.27 0.37 2.44e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4969178 0.965 rs938351 chr17:76399404 C/T cg20026190 chr17:76395443 PGS1 0.45 7.15 0.36 5.17e-12 HDL cholesterol levels; LIHC cis rs7149337 0.837 rs10132658 chr14:51677599 C/T cg23942311 chr14:51606299 NA 0.35 6.9 0.35 2.57e-11 Cancer; LIHC cis rs7647973 0.626 rs1996664 chr3:49878395 A/G cg03060546 chr3:49711283 APEH -0.59 -6.95 -0.35 1.87e-11 Menarche (age at onset); LIHC cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg06873352 chr17:61820015 STRADA 0.61 9.46 0.46 5.17e-19 Height; LIHC cis rs116095464 0.558 rs7710005 chr5:233572 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.67 -0.5 3.83e-23 Breast cancer; LIHC cis rs1008375 0.898 rs7678654 chr4:17575376 T/G cg02297831 chr4:17616191 MED28 0.47 7.05 0.36 1e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2153535 0.580 rs2225765 chr6:8481785 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.88 0.54 1.78e-27 Motion sickness; LIHC cis rs1580019 0.563 rs10486509 chr7:32585443 C/G cg14728415 chr7:32535168 LSM5;AVL9 -0.4 -5.74 -0.3 2.05e-8 Cognitive ability; LIHC cis rs2932538 0.922 rs6671645 chr1:113129128 A/G cg22162597 chr1:113214053 CAPZA1 0.68 10.69 0.5 3.45e-23 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs7772486 0.754 rs4896832 chr6:145964151 G/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.95 -0.31 6.62e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8081395 0.834 rs11650106 chr17:57850251 C/T cg13753209 chr17:57696993 CLTC -0.45 -6.9 -0.35 2.5e-11 White blood cell count; LIHC cis rs992157 0.764 rs2891076 chr2:219184398 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.72 10.15 0.48 2.48e-21 Colorectal cancer; LIHC cis rs77633900 0.772 rs284901 chr15:76747761 C/T cg21673338 chr15:77095150 SCAPER -0.53 -5.93 -0.31 7.23e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs2303759 0.918 rs2288480 chr19:49867016 C/G cg22307029 chr19:49891270 CCDC155 0.57 9.3 0.45 1.75e-18 Multiple sclerosis; LIHC cis rs769267 0.930 rs1054284 chr19:19616953 T/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.38 5.77 0.3 1.81e-8 Tonsillectomy; LIHC cis rs9596863 0.898 rs13378790 chr13:54372312 T/C ch.13.53330881F chr13:54432880 NA 0.43 5.74 0.3 2.1e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs909341 0.909 rs1151622 chr20:62365556 A/G cg03999872 chr20:62272968 STMN3 -0.46 -6.84 -0.35 3.6e-11 Atopic dermatitis; LIHC cis rs7659604 0.605 rs67772833 chr4:122723106 G/A cg19671926 chr4:122722719 EXOSC9 -0.41 -5.78 -0.3 1.65e-8 Type 2 diabetes; LIHC cis rs853679 0.517 rs4711165 chr6:28115184 T/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs2180341 0.814 rs6919277 chr6:127738050 T/C cg27446573 chr6:127587934 RNF146 0.81 13.06 0.58 6.5e-32 Breast cancer; LIHC cis rs4820539 0.933 rs2267004 chr22:23459863 G/A cg21100191 chr22:23484243 RTDR1 0.86 15.29 0.64 1.4e-40 Bone mineral density; LIHC cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg21280719 chr6:42927975 GNMT -0.31 -7.04 -0.36 1.09e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg01518246 chr11:63870912 FLRT1;MACROD1 0.44 6.04 0.31 4.02e-9 Mean platelet volume; LIHC cis rs858239 0.539 rs6945510 chr7:23192240 C/T cg23682824 chr7:23144976 KLHL7 0.45 6.77 0.34 5.72e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs875971 0.862 rs13232191 chr7:65986648 A/G cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.34e-9 Aortic root size; LIHC trans rs12478296 0.792 rs6738361 chr2:243014257 C/T cg01596870 chr19:55963115 NA -0.62 -7.48 -0.37 6.14e-13 Obesity-related traits; LIHC cis rs9905704 0.647 rs11650809 chr17:56972741 A/G cg05425664 chr17:57184151 TRIM37 -0.44 -6.18 -0.32 1.82e-9 Testicular germ cell tumor; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01025762 chr7:107531363 DLD 0.52 7.22 0.36 3.35e-12 Pancreatic cancer; LIHC cis rs62064224 0.702 rs735555 chr17:30817450 A/G cg18200150 chr17:30822561 MYO1D -0.43 -6.8 -0.35 4.74e-11 Schizophrenia; LIHC cis rs4975616 0.869 rs452384 chr5:1330840 T/C cg26373071 chr5:1325741 CLPTM1L 0.35 5.73 0.3 2.25e-8 Lung cancer; LIHC cis rs11031096 0.727 rs2268168 chr11:4142069 C/T cg18678763 chr11:4115507 RRM1 -0.57 -8.62 -0.42 2.58e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs6831352 0.703 rs2602862 chr4:100033221 A/G cg12011299 chr4:100065546 ADH4 0.56 9.84 0.47 2.69e-20 Alcohol dependence; LIHC cis rs7945705 0.967 rs34842234 chr11:8891894 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.07 0.36 8.65e-12 Hemoglobin concentration; LIHC cis rs2228479 0.702 rs62052710 chr16:89854893 C/T cg19635926 chr16:89946313 TCF25 0.53 6.5 0.33 2.8e-10 Skin colour saturation; LIHC cis rs568617 0.953 rs645900 chr11:65648135 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.44 -6.44 -0.33 4.17e-10 Crohn's disease; LIHC cis rs2066819 0.892 rs2066807 chr12:56740682 C/G cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs963731 0.579 rs997344 chr2:39281730 G/C cg04010122 chr2:39346883 SOS1 -0.66 -6.08 -0.31 3.3e-9 Corticobasal degeneration; LIHC cis rs80282103 0.764 rs7093915 chr10:1107341 A/G cg08668510 chr10:1095578 IDI1 -0.71 -7.37 -0.37 1.3e-12 Glomerular filtration rate (creatinine); LIHC cis rs72634258 0.945 rs36016881 chr1:8051241 A/G cg00042356 chr1:8021962 PARK7 0.89 8.69 0.43 1.55e-16 Inflammatory bowel disease; LIHC trans rs2243480 1.000 rs34974928 chr7:65364006 T/C cg10756647 chr7:56101905 PSPH 1.09 13.38 0.59 4.07e-33 Diabetic kidney disease; LIHC cis rs7116495 0.609 rs7126394 chr11:71685429 A/G cg26138937 chr11:71823887 C11orf51 -1.31 -10.34 -0.49 5.49e-22 Severe influenza A (H1N1) infection; LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg05896524 chr21:47604654 C21orf56 -0.49 -7.91 -0.39 3.7e-14 Testicular germ cell tumor; LIHC cis rs7116495 0.609 rs628025 chr11:71802351 A/C cg26138937 chr11:71823887 C11orf51 -1.32 -9.94 -0.47 1.33e-20 Severe influenza A (H1N1) infection; LIHC cis rs881375 0.967 rs2109896 chr9:123683106 C/T cg14580859 chr9:123691850 NA 0.38 6.73 0.34 7.08e-11 Rheumatoid arthritis; LIHC cis rs12824058 0.831 rs4759653 chr12:130812604 T/C cg24838063 chr12:130822603 PIWIL1 0.67 9.86 0.47 2.31e-20 Menopause (age at onset); LIHC cis rs9596863 0.847 rs4537884 chr13:54327936 A/G ch.13.53330881F chr13:54432880 NA 0.44 6.06 0.31 3.56e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs6693567 0.565 rs2264417 chr1:150368501 C/T cg15654264 chr1:150340011 RPRD2 0.49 8.13 0.4 7.9e-15 Migraine; LIHC cis rs763121 1.000 rs138464 chr22:38906432 C/T cg06022373 chr22:39101656 GTPBP1 -0.6 -11.04 -0.51 1.92e-24 Menopause (age at onset); LIHC cis rs1559088 1.000 rs1559087 chr19:33551041 A/G cg17764715 chr19:33622953 WDR88 0.4 5.72 0.3 2.29e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24141233 chr1:212781895 ATF3 0.54 6.92 0.35 2.22e-11 Lung function (FEV1/FVC); LIHC cis rs55665837 0.540 rs10832294 chr11:14747427 C/A cg00085434 chr11:14927489 NA 0.4 5.79 0.3 1.56e-8 Vitamin D levels; LIHC cis rs55665837 1.000 rs10832275 chr11:14478224 A/C cg19336497 chr11:14380999 RRAS2 -0.45 -8.26 -0.41 3.24e-15 Vitamin D levels; LIHC trans rs7618501 1.000 rs35261599 chr3:49773236 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs9457247 0.765 rs9295385 chr6:167448181 A/G cg12798992 chr6:167411361 FGFR1OP 0.56 7.8 0.39 7.78e-14 Crohn's disease; LIHC cis rs74181299 0.684 rs6741255 chr2:65306905 C/T cg05010058 chr2:65284262 CEP68 -0.4 -6.61 -0.34 1.44e-10 Pulse pressure; LIHC trans rs10506458 1.000 rs17763435 chr12:63416511 A/G cg22491629 chr6:157744540 C6orf35 0.55 9.95 0.47 1.14e-20 Hemostatic factors and hematological phenotypes; LIHC cis rs10752881 1.000 rs8179262 chr1:182973186 C/T ch.1.3577855R chr1:183094577 LAMC1 0.58 9.93 0.47 1.36e-20 Colorectal cancer; LIHC cis rs17401966 0.838 rs1013953 chr1:10319459 T/A cg15208524 chr1:10270712 KIF1B 0.37 5.72 0.3 2.3e-8 Hepatocellular carcinoma; LIHC cis rs4466137 0.794 rs975595 chr5:83010095 G/A cg16102102 chr5:83017553 HAPLN1 -0.43 -6.67 -0.34 1.04e-10 Prostate cancer; LIHC cis rs4919087 0.962 rs10786324 chr10:99054387 A/G cg25902810 chr10:99078978 FRAT1 0.69 10.28 0.49 8.68e-22 Monocyte count; LIHC cis rs1185460 0.967 rs1784459 chr11:118938388 C/A cg23280166 chr11:118938394 VPS11 0.6 8.12 0.4 8.39e-15 Coronary artery disease; LIHC cis rs2857078 0.627 rs1476512 chr17:42330122 C/T cg13607699 chr17:42295918 UBTF -0.48 -7.96 -0.4 2.5e-14 Red cell distribution width;Reticulocyte count; LIHC cis rs3008870 1.000 rs2985795 chr1:67426223 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.29 0.66 1.46e-44 Lymphocyte percentage of white cells; LIHC cis rs4665809 1.000 rs12475854 chr2:26267375 G/A cg04944784 chr2:26401820 FAM59B -0.68 -8.71 -0.43 1.37e-16 Gut microbiome composition (summer); LIHC cis rs600806 0.778 rs6693932 chr1:110003575 T/C cg08911820 chr1:110026001 ATXN7L2 -0.62 -7.31 -0.37 1.87e-12 Intelligence (multi-trait analysis); LIHC cis rs4478858 0.735 rs7523438 chr1:31788313 C/T cg00250761 chr1:31883323 NA 0.31 7.52 0.38 4.8e-13 Alcohol dependence; LIHC cis rs9768139 0.708 rs11769028 chr7:158113881 G/A cg25566285 chr7:158114605 PTPRN2 0.22 6.03 0.31 4.25e-9 Calcium levels; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg10755058 chr3:40428713 ENTPD3 -0.4 -6.92 -0.35 2.2e-11 Renal cell carcinoma; LIHC trans rs9951602 0.512 rs1903722 chr18:76646539 G/A cg02800362 chr5:177631904 HNRNPAB 0.67 10.61 0.5 6.34e-23 Obesity-related traits; LIHC cis rs9896933 0.723 rs7224189 chr17:80782227 C/T cg15664640 chr17:80829946 TBCD -0.58 -6.25 -0.32 1.25e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC trans rs6598955 0.671 rs12141563 chr1:26589636 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.59 -0.42 3.07e-16 Obesity-related traits; LIHC cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg06238570 chr21:40685208 BRWD1 0.6 7.3 0.37 1.98e-12 Cognitive function; LIHC cis rs7428 0.545 rs7572750 chr2:85552186 C/A cg24342717 chr2:85555507 TGOLN2 -0.79 -10.2 -0.48 1.67e-21 Ear protrusion; LIHC cis rs425277 1.000 rs262672 chr1:2080813 G/T cg24578937 chr1:2090814 PRKCZ 0.5 8.89 0.43 3.64e-17 Height; LIHC cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 9.34 0.45 1.25e-18 Bipolar disorder; LIHC cis rs6144337 1 rs6144337 chr11:47284302 TCCATGTGCCTCA/T cg26139080 chr11:47293733 MADD -0.42 -5.89 -0.3 9.26e-9 Lymphocyte percentage of white cells; LIHC cis rs6066825 0.627 rs6019349 chr20:47275245 A/G cg18078177 chr20:47281410 PREX1 0.44 7.31 0.37 1.96e-12 Colorectal cancer; LIHC cis rs6882046 0.533 rs599402 chr5:88043656 G/C cg22951263 chr5:87985283 NA -0.39 -6.73 -0.34 7.13e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs2153535 0.580 rs6597335 chr6:8527714 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs4242434 0.536 rs1871900 chr8:22481449 A/G cg03733263 chr8:22462867 KIAA1967 0.54 8.92 0.43 2.94e-17 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg12751644 chr20:60527061 NA -0.52 -8.63 -0.42 2.32e-16 Obesity-related traits; LIHC cis rs3806843 1.000 rs10072015 chr5:140170655 A/T cg26395211 chr5:140044315 WDR55 0.43 6.34 0.32 7.35e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs4900538 0.963 rs1885708 chr14:102960164 A/G cg18135206 chr14:102964638 TECPR2 0.94 15.93 0.65 3.95e-43 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1997103 0.834 rs10274457 chr7:55390199 G/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.39e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7552404 0.889 rs380075 chr1:76106961 T/A cg03433033 chr1:76189801 ACADM -0.69 -9.95 -0.47 1.23e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs651907 0.514 rs12636047 chr3:101434449 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.69 11.46 0.53 5.85e-26 Colorectal cancer; LIHC trans rs1814175 0.715 rs11040586 chr11:49858432 T/A cg03929089 chr4:120376271 NA -0.89 -18.62 -0.71 6.08e-54 Height; LIHC cis rs61990749 0.544 rs3759728 chr14:78230159 A/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.83 -0.39 5.99e-14 Fibroblast growth factor basic levels; LIHC cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg27297192 chr10:134578999 INPP5A 0.55 7.56 0.38 3.74e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4243830 0.850 rs6679649 chr1:6606608 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 0.87 12.4 0.56 2.01e-29 Body mass index; LIHC cis rs9318086 0.534 rs12428855 chr13:24382961 A/C cg25267304 chr13:24462978 PCOTH;MIPEP -0.35 -5.72 -0.3 2.34e-8 Myopia (pathological); LIHC cis rs6942756 0.688 rs2718089 chr7:128927022 G/T cg02491457 chr7:128862824 NA 0.57 8.46 0.42 7.85e-16 White matter hyperintensity burden; LIHC trans rs12702919 0.692 rs6961826 chr7:9558915 T/C cg22961275 chr19:40005758 SELV -0.4 -6.04 -0.31 4.11e-9 PR interval in Tripanosoma cruzi seropositivity; LIHC cis rs7107174 1.000 rs4944198 chr11:78032605 T/A cg02023728 chr11:77925099 USP35 0.5 9.49 0.46 4.15e-19 Testicular germ cell tumor; LIHC cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg03806693 chr22:41940476 POLR3H -0.99 -11.44 -0.53 6.81e-26 Vitiligo; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg00280220 chr17:61926910 NA 0.42 6.89 0.35 2.73e-11 Prudent dietary pattern; LIHC cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg00166722 chr3:10149974 C3orf24 0.53 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC cis rs708547 0.647 rs1718830 chr4:57888510 T/C cg16868167 chr4:57843880 C4orf14;POLR2B 0.45 6.59 0.34 1.63e-10 Response to bleomycin (chromatid breaks); LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.23 -0.32 1.36e-9 Menopause (age at onset); LIHC cis rs10540 1.000 rs12419716 chr11:503385 C/G cg03352830 chr11:487213 PTDSS2 0.8 6.82 0.35 4.15e-11 Body mass index; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs34779708 0.742 rs35912711 chr10:35312996 T/C cg03585969 chr10:35415529 CREM 0.77 11.55 0.53 2.86e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9486719 1.000 rs11152968 chr6:96908653 A/G cg06623918 chr6:96969491 KIAA0776 0.64 6.81 0.35 4.51e-11 Migraine;Coronary artery disease; LIHC cis rs7149242 0.922 rs9671394 chr14:101159674 C/T cg11726507 chr14:101155519 NA -0.27 -5.98 -0.31 5.6e-9 Platelet count; LIHC cis rs1580019 0.587 rs7806941 chr7:32553319 G/T cg07520158 chr7:32535189 LSM5;AVL9 0.61 8.94 0.44 2.48e-17 Cognitive ability; LIHC cis rs2257205 0.667 rs9909635 chr17:56752159 G/A cg05425664 chr17:57184151 TRIM37 -0.59 -6.47 -0.33 3.49e-10 Pancreatic cancer; LIHC cis rs7582180 0.585 rs12999151 chr2:100939333 G/A cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs2050392 0.590 rs694346 chr10:30711929 C/T cg25182066 chr10:30743637 MAP3K8 -0.61 -9.79 -0.47 4.25e-20 Inflammatory bowel disease; LIHC cis rs9486715 0.758 rs9386528 chr6:96928514 G/A cg18709589 chr6:96969512 KIAA0776 -0.34 -5.81 -0.3 1.41e-8 Headache; LIHC cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg18357526 chr6:26021779 HIST1H4A -0.54 -7.13 -0.36 6.01e-12 Blood metabolite levels; LIHC cis rs34779708 0.733 rs16935948 chr10:35549748 C/G cg03585969 chr10:35415529 CREM 0.71 10.08 0.48 4.44e-21 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9790314 0.936 rs466399 chr3:161091194 G/T cg03342759 chr3:160939853 NMD3 -0.64 -7.7 -0.38 1.44e-13 Morning vs. evening chronotype; LIHC cis rs7173389 0.530 rs6495063 chr15:73682708 G/T cg01796676 chr15:73680284 NA 0.53 8.59 0.42 3.07e-16 Resting heart rate; LIHC cis rs965469 1.000 rs2236117 chr20:3302021 T/C cg25506879 chr20:3388711 C20orf194 -0.55 -6.74 -0.34 6.9e-11 IFN-related cytopenia; LIHC cis rs2066819 1.000 rs58852079 chr12:56706922 A/C cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs10751667 0.643 rs10902245 chr11:953014 C/T cg06064525 chr11:970664 AP2A2 0.54 14.17 0.61 3.61e-36 Alzheimer's disease (late onset); LIHC cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg05564831 chr3:52568323 NT5DC2 0.36 5.93 0.31 7.39e-9 Electroencephalogram traits; LIHC cis rs7412746 0.658 rs59988025 chr1:150940358 C/T cg17724175 chr1:150552817 MCL1 0.41 8.05 0.4 1.34e-14 Melanoma; LIHC cis rs35740288 0.580 rs34526042 chr15:86339956 C/T cg20737812 chr15:86336631 KLHL25 -0.44 -6.1 -0.31 2.83e-9 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC trans rs17685 0.753 rs1637039 chr7:75693009 C/T cg19862616 chr7:65841803 NCRNA00174 0.92 19.18 0.72 3.65e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9911578 0.967 rs686425 chr17:56776730 A/G cg12560992 chr17:57184187 TRIM37 0.98 17.69 0.69 3.49e-50 Intelligence (multi-trait analysis); LIHC cis rs9916302 0.861 rs8081033 chr17:37506650 A/G cg03013999 chr17:37608204 MED1 -0.36 -5.99 -0.31 5.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg13409248 chr3:40428643 ENTPD3 0.41 6.62 0.34 1.37e-10 Renal cell carcinoma; LIHC cis rs11696739 0.536 rs11696842 chr20:1600794 C/T cg15722679 chr20:1638393 SIRPG 0.54 9.78 0.47 4.43e-20 Mean platelet volume; LIHC cis rs1005277 1.000 rs1005277 chr10:38218259 A/C cg00409905 chr10:38381863 ZNF37A 0.47 7.14 0.36 5.79e-12 Extrinsic epigenetic age acceleration; LIHC cis rs2075165 0.836 rs7512751 chr1:156234439 T/G cg08469215 chr1:156261351 TMEM79 0.39 6.24 0.32 1.27e-9 Tonsillectomy; LIHC cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg10360323 chr17:41437877 NA 0.41 6.07 0.31 3.37e-9 Menopause (age at onset); LIHC cis rs2274273 0.624 rs7155954 chr14:55750943 G/A cg01864836 chr14:55583639 NA -0.35 -5.8 -0.3 1.48e-8 Protein biomarker; LIHC trans rs11098499 0.866 rs6847778 chr4:120293582 A/G cg25214090 chr10:38739885 LOC399744 0.49 7.8 0.39 7.47e-14 Corneal astigmatism; LIHC cis rs3857067 0.530 rs17021364 chr4:95047893 C/T cg11021082 chr4:95130006 SMARCAD1 0.41 6.72 0.34 7.78e-11 QT interval; LIHC cis rs17539620 0.624 rs62432736 chr6:154834401 A/G cg20019720 chr6:154832845 CNKSR3 0.43 6.49 0.33 3.02e-10 Lipoprotein (a) levels; LIHC cis rs801193 0.569 rs6951302 chr7:66132512 T/C cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs6450176 0.859 rs3776719 chr5:53298684 T/G ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.6 -0.62 7.2e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs4474465 0.920 rs7947852 chr11:78198030 T/C cg27205649 chr11:78285834 NARS2 -0.4 -6.24 -0.32 1.33e-9 Alzheimer's disease (survival time); LIHC cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg06634786 chr22:41940651 POLR3H -0.83 -9.04 -0.44 1.15e-17 Vitiligo; LIHC cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg26338869 chr17:61819248 STRADA 0.61 8.91 0.43 3.16e-17 Prudent dietary pattern; LIHC cis rs1882538 0.506 rs7805858 chr7:133126589 G/T cg10665199 chr7:133106180 EXOC4 0.52 8.59 0.42 3.2e-16 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.967 rs60176674 chr17:28479854 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.78 0.43 7.96e-17 Coffee consumption (cups per day); LIHC cis rs9918079 0.542 rs12499412 chr4:15602252 G/C cg16509355 chr4:15471240 CC2D2A 0.46 7.1 0.36 7.27e-12 Obesity-related traits; LIHC cis rs754466 0.958 rs11002341 chr10:79701363 A/C cg17075019 chr10:79541650 NA -0.58 -7.55 -0.38 4.12e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11690935 1.000 rs312924 chr2:172564021 A/T cg13550731 chr2:172543902 DYNC1I2 0.86 16.76 0.67 1.89e-46 Schizophrenia; LIHC cis rs637571 0.522 rs12792888 chr11:65761446 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.08 0.44 9.13e-18 Eosinophil percentage of white cells; LIHC cis rs10751667 0.714 rs7395879 chr11:963855 G/C cg10932868 chr11:921992 NA 0.4 7.48 0.38 6.23e-13 Alzheimer's disease (late onset); LIHC cis rs9733 0.596 rs6587518 chr1:150661787 T/C cg15448220 chr1:150897856 SETDB1 0.4 6.3 0.32 9.39e-10 Tonsillectomy; LIHC cis rs2806561 0.765 rs2806556 chr1:23502850 G/A cg19743168 chr1:23544995 NA 0.35 5.96 0.31 6.14e-9 Height; LIHC cis rs6450176 0.564 rs6874524 chr5:53343529 C/T ch.5.1024479R chr5:53302184 ARL15 0.72 13.07 0.58 6e-32 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2302190 0.882 rs7213415 chr17:56672433 C/G cg05425664 chr17:57184151 TRIM37 -0.47 -5.89 -0.3 9.43e-9 Vitamin D levels; LIHC cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs17776563 0.959 rs28687418 chr15:89115862 G/A cg05013243 chr15:89149849 MIR1179 0.46 7.56 0.38 3.85e-13 Thyroid hormone levels; LIHC cis rs7677751 0.806 rs61320297 chr4:55088175 G/A cg17187183 chr4:55093834 PDGFRA 0.67 8.4 0.41 1.2e-15 Corneal astigmatism; LIHC cis rs11098499 0.863 rs1552092 chr4:120488496 C/T cg09307838 chr4:120376055 NA 0.75 11.43 0.53 7.8e-26 Corneal astigmatism; LIHC cis rs9814567 1.000 rs4423809 chr3:134300107 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.24 0.55 8.15e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6429082 0.806 rs2382570 chr1:235570523 G/A cg26050004 chr1:235667680 B3GALNT2 -0.4 -6.14 -0.31 2.35e-9 Adiposity; LIHC cis rs929354 0.772 rs2051876 chr7:157009037 A/G cg16102536 chr7:156981717 UBE3C -0.35 -5.94 -0.31 7.12e-9 Body mass index; LIHC cis rs7715806 0.500 rs17649248 chr5:74998426 C/T cg00601450 chr5:74908170 NA 0.58 6.94 0.35 2.02e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.37 0.33 6.11e-10 Bipolar disorder; LIHC cis rs6690583 1.000 rs6690464 chr1:85466369 A/G cg22153463 chr1:85462885 MCOLN2 -0.46 -6.11 -0.31 2.64e-9 Serum sulfate level; LIHC cis rs17345786 0.861 rs11707689 chr3:101086475 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.57 7.09 0.36 7.92e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.66 11.19 0.52 5.46e-25 Menarche (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08528519 chr14:100659610 NA -0.43 -6.24 -0.32 1.3e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs12477438 0.765 rs1453564 chr2:99564428 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.4 -0.37 1.04e-12 Chronic sinus infection; LIHC cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg05590025 chr7:65112418 INTS4L2 -0.57 -6.25 -0.32 1.2e-9 Diabetic kidney disease; LIHC cis rs3096299 0.874 rs3102342 chr16:89451575 T/C cg08822215 chr16:89438651 ANKRD11 -0.45 -7.01 -0.35 1.25e-11 Multiple myeloma (IgH translocation); LIHC cis rs7224685 0.859 rs34348519 chr17:4094140 G/C cg09597638 chr17:3907349 NA 0.52 7.19 0.36 4.18e-12 Type 2 diabetes; LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg00684032 chr4:1343700 KIAA1530 0.37 5.94 0.31 7.1e-9 Obesity-related traits; LIHC cis rs7772486 0.790 rs9386141 chr6:146268623 T/A cg05347473 chr6:146136440 FBXO30 -0.35 -5.74 -0.3 2.12e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.921 rs5751081 chr22:41742788 A/T cg03806693 chr22:41940476 POLR3H -0.46 -6.04 -0.31 3.91e-9 Vitiligo; LIHC cis rs317689 0.680 rs315140 chr12:69790780 A/T cg19645103 chr12:69753606 YEATS4 -0.46 -6.32 -0.32 8.22e-10 Response to diuretic therapy; LIHC cis rs12701220 0.901 rs12701713 chr7:1090505 G/A cg04025307 chr7:1156635 C7orf50 0.44 5.81 0.3 1.44e-8 Bronchopulmonary dysplasia; LIHC cis rs10792665 0.902 rs7928520 chr11:82654471 T/C cg24227371 chr11:82718527 RAB30 -0.3 -6.89 -0.35 2.63e-11 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18603276 chr17:8023961 HES7 0.47 6.11 0.31 2.66e-9 Lung function (FEV1/FVC); LIHC trans rs7618501 1.000 rs11130219 chr3:49752427 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg05025164 chr4:1340916 KIAA1530 -0.66 -9.96 -0.47 1.08e-20 Obesity-related traits; LIHC cis rs1348850 0.574 rs11691740 chr2:178445161 A/G cg27490568 chr2:178487706 NA -0.96 -11.7 -0.53 7.99e-27 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg13986249 chr9:37903631 MCART1 -0.43 -6.11 -0.31 2.66e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6430585 0.528 rs309172 chr2:136674028 A/G cg07169764 chr2:136633963 MCM6 1.01 15.8 0.65 1.26e-42 Corneal structure; LIHC cis rs7903847 0.642 rs11189196 chr10:99155079 A/G cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.53e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9457247 1.000 rs439553 chr6:167391212 A/G cg12798992 chr6:167411361 FGFR1OP 0.59 9.78 0.47 4.38e-20 Crohn's disease; LIHC cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg08888203 chr3:10149979 C3orf24 0.59 6.73 0.34 7.03e-11 Alzheimer's disease; LIHC cis rs7927771 0.965 rs4752845 chr11:47539697 T/C cg20135002 chr11:47629003 NA -0.57 -10.07 -0.48 4.6e-21 Subjective well-being; LIHC cis rs921968 0.541 rs933995 chr2:219650718 G/A cg02985541 chr2:219472218 PLCD4 -0.35 -6.12 -0.31 2.62e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs5769707 0.967 rs5769698 chr22:49997706 A/G cg01652190 chr22:50026171 C22orf34 -0.31 -7.23 -0.36 3.16e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6831352 0.877 rs2602890 chr4:100043179 C/T cg12011299 chr4:100065546 ADH4 0.61 10.29 0.49 7.89e-22 Alcohol dependence; LIHC cis rs2303759 0.709 rs10411679 chr19:49826480 A/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.53 7.89 0.39 4.02e-14 Multiple sclerosis; LIHC cis rs3096299 0.935 rs3114890 chr16:89449546 C/G cg06640241 chr16:89574553 SPG7 0.64 9.97 0.47 1.04e-20 Multiple myeloma (IgH translocation); LIHC trans rs875971 0.545 rs12673308 chr7:65631361 C/A cg26939375 chr7:64535504 NA 0.41 6.47 0.33 3.36e-10 Aortic root size; LIHC cis rs6750047 0.605 rs59501228 chr2:38261972 A/C cg07380506 chr2:38303506 CYP1B1 -0.59 -7.45 -0.37 7.81e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs1568889 0.838 rs716366 chr11:28121536 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 13.92 0.6 3.4000000000000003e-35 Bipolar disorder; LIHC cis rs769267 0.930 rs10282 chr19:19619317 T/C cg03709012 chr19:19516395 GATAD2A 1.01 17.93 0.7 3.71e-51 Tonsillectomy; LIHC cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.3 -0.45 1.65e-18 Bipolar disorder; LIHC cis rs68170813 0.559 rs7803290 chr7:106907353 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs2075371 0.637 rs13245165 chr7:133951492 A/T cg20476274 chr7:133979776 SLC35B4 0.7 9.37 0.45 1.05e-18 Mean platelet volume; LIHC cis rs10416265 0.516 rs1270252 chr19:33623604 G/A cg27124370 chr19:33622961 WDR88 -0.49 -6.89 -0.35 2.62e-11 Bone properties (heel); LIHC cis rs7246657 0.943 rs4801759 chr19:37954985 G/A cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs7208859 0.673 rs28588622 chr17:29245699 G/A cg13385521 chr17:29058706 SUZ12P 0.79 7.8 0.39 7.67e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7072216 0.763 rs3814142 chr10:100171104 C/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs7223966 1.000 rs9899788 chr17:61756384 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.92e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4919694 1.000 rs12254254 chr10:104765605 C/T cg04362960 chr10:104952993 NT5C2 1.14 9.03 0.44 1.28e-17 Arsenic metabolism; LIHC cis rs7772486 0.790 rs4314514 chr6:146260010 A/G cg05347473 chr6:146136440 FBXO30 -0.36 -5.86 -0.3 1.07e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9611565 0.532 rs4401299 chr22:42156517 A/G cg06634786 chr22:41940651 POLR3H 0.57 6.17 0.32 1.95e-9 Vitiligo; LIHC trans rs6887276 0.504 rs1003136 chr5:127347815 A/G cg16011800 chr17:1958478 HIC1 -0.39 -6.06 -0.31 3.69e-9 Height; LIHC cis rs864643 1.000 rs1768261 chr3:39551985 G/A cg05136238 chr3:39556330 MOBP 0.31 5.83 0.3 1.31e-8 Attention deficit hyperactivity disorder; LIHC cis rs2204008 0.837 rs4312131 chr12:38181087 G/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 6.11 0.31 2.66e-9 Schizophrenia; LIHC cis rs600806 0.850 rs11102976 chr1:109917540 G/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.92 -0.3 7.87e-9 Intelligence (multi-trait analysis); LIHC cis rs7116495 0.609 rs949326 chr11:71730306 A/G cg26138937 chr11:71823887 C11orf51 1.21 10.32 0.49 6.46e-22 Severe influenza A (H1N1) infection; LIHC cis rs2625529 0.824 rs12439900 chr15:72373640 A/G cg16672083 chr15:72433130 SENP8 -0.31 -5.87 -0.3 1.06e-8 Red blood cell count; LIHC cis rs546131 0.928 rs558967 chr11:34827168 T/A cg11058730 chr11:34937778 PDHX;APIP 0.61 9.22 0.45 3.1e-18 Lung disease severity in cystic fibrosis; LIHC cis rs2274273 0.870 rs4496026 chr14:55790512 A/G cg01864836 chr14:55583639 NA -0.37 -6.57 -0.33 1.9e-10 Protein biomarker; LIHC cis rs4925386 1.000 rs1889201 chr20:60923075 C/T cg03945807 chr20:60948434 NA -0.35 -6.37 -0.33 5.94e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs4665809 1.000 rs11126375 chr2:26344787 G/A cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs2637266 0.967 rs4979898 chr10:78355672 G/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs7312933 0.558 rs11181502 chr12:42823833 A/G cg17420585 chr12:42539391 GXYLT1 -0.35 -5.72 -0.3 2.34e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11112613 0.713 rs68053161 chr12:105950035 G/C cg03607813 chr12:105948248 NA 0.67 13.37 0.59 4.49e-33 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs12477438 0.765 rs7340412 chr2:99661148 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.43 7.36 0.37 1.39e-12 Bipolar disorder; LIHC cis rs317689 0.690 rs604168 chr12:69671158 C/T cg19645103 chr12:69753606 YEATS4 -0.45 -6.04 -0.31 3.93e-9 Response to diuretic therapy; LIHC cis rs6466055 0.720 rs7357199 chr7:105019355 G/C cg04380332 chr7:105027541 SRPK2 -0.38 -7.02 -0.35 1.2e-11 Schizophrenia; LIHC cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg00149659 chr3:10157352 C3orf10 0.68 7.12 0.36 6.57e-12 Alzheimer's disease; LIHC cis rs1144333 0.850 rs1146651 chr1:76273594 C/A cg22875332 chr1:76189707 ACADM -0.42 -6.78 -0.34 5.34e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs2795502 1.000 rs2185717 chr10:43343875 G/A cg20628663 chr10:43360327 NA 0.46 7.2 0.36 3.83e-12 Blood protein levels; LIHC cis rs2016586 0.802 rs5999973 chr22:36115594 G/A cg26342177 chr22:36113512 APOL5 -0.39 -6.57 -0.33 1.82e-10 Body mass index; LIHC trans rs2243480 1.000 rs36068983 chr7:65408991 C/T cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs7647973 0.626 rs11130217 chr3:49737323 A/G cg03060546 chr3:49711283 APEH 0.59 6.82 0.35 4.12e-11 Menarche (age at onset); LIHC cis rs2380220 0.808 rs2613548 chr6:95910559 C/T cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs796364 1.000 rs769949 chr2:200729558 A/G cg23649088 chr2:200775458 C2orf69 0.49 5.85 0.3 1.18e-8 Schizophrenia; LIHC trans rs60752752 0.852 rs4772 chr1:153346263 C/T cg14901121 chr8:98817630 LAPTM4B 0.44 7.04 0.36 1.08e-11 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs1789 0.903 rs6850422 chr4:15682437 C/T cg21329975 chr4:15471214 CC2D2A -0.4 -5.9 -0.3 8.89e-9 Blood protein levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26119740 chr11:73881915 C2CD3;PPME1 0.45 6.43 0.33 4.19e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618501 1.000 rs7431106 chr3:49808374 G/A cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.34e-11 Intelligence (multi-trait analysis); LIHC cis rs17125944 0.615 rs1886785 chr14:53312106 A/C cg00686598 chr14:53173677 PSMC6 -0.78 -9.33 -0.45 1.36e-18 Alzheimer's disease (late onset); LIHC cis rs4722166 0.508 rs2069832 chr7:22767433 A/G cg05472934 chr7:22766657 IL6 0.53 8.44 0.42 8.9e-16 Lung cancer; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg22887498 chr19:39401301 NA 0.42 6.27 0.32 1.08e-9 Alopecia areata; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg04775238 chr2:202646121 ALS2 0.31 6.07 0.31 3.38e-9 Calcium levels; LIHC cis rs35883536 1.000 rs4908087 chr1:101088594 C/T cg14515779 chr1:101123966 NA -0.68 -13.14 -0.58 3.21e-32 Monocyte count; LIHC cis rs3768617 0.811 rs4350171 chr1:182982148 C/T ch.1.3577855R chr1:183094577 LAMC1 0.48 7.55 0.38 4.03e-13 Fuchs's corneal dystrophy; LIHC cis rs9640161 0.742 rs2159236 chr7:150017214 A/G cg21361702 chr7:150065534 REPIN1 0.48 6.61 0.34 1.45e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs8062405 1.000 rs1987472 chr16:28825777 C/T cg07451762 chr16:28383216 NA 0.34 6.47 0.33 3.31e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs895636 0.749 rs748947 chr2:45192600 A/C cg16198908 chr2:45192207 NA 0.39 5.77 0.3 1.77e-8 Metabolite levels;Fasting plasma glucose; LIHC cis rs7584330 0.554 rs75918156 chr2:238426287 G/A cg08992911 chr2:238395768 MLPH 0.49 5.98 0.31 5.6e-9 Prostate cancer; LIHC cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg13047869 chr3:10149882 C3orf24 0.55 6.93 0.35 2.08e-11 Alzheimer's disease; LIHC cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg09913183 chr17:42254507 C17orf65;ASB16 -0.79 -11.94 -0.54 1.02e-27 Total body bone mineral density; LIHC cis rs7945705 0.902 rs7930026 chr11:9013639 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.38 5.97 0.31 6.05e-9 Hemoglobin concentration; LIHC trans rs1945213 0.694 rs34390414 chr11:55863367 T/G cg15704280 chr7:45808275 SEPT13 0.62 8.12 0.4 8.69e-15 Acute lymphoblastic leukemia (childhood); LIHC cis rs801193 0.935 rs2659916 chr7:66151352 C/G cg18876405 chr7:65276391 NA 0.43 7.36 0.37 1.34e-12 Aortic root size; LIHC trans rs6866721 0.755 rs10062108 chr5:116215157 T/C cg07571379 chr11:134631427 NA -0.29 -6.09 -0.31 3.08e-9 Body mass index; LIHC cis rs3806843 0.568 rs2530232 chr5:140082878 A/G cg26395211 chr5:140044315 WDR55 0.41 5.89 0.3 9.4e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs614226 1.000 rs591992 chr12:121019323 T/C cg01236616 chr12:121019343 POP5 1.23 18.12 0.7 6.75e-52 Type 1 diabetes nephropathy; LIHC cis rs4699052 0.963 rs11733615 chr4:104157164 C/T cg16532752 chr4:104119610 CENPE -0.4 -6.21 -0.32 1.56e-9 Testicular germ cell tumor; LIHC trans rs875971 0.545 rs7783889 chr7:65748353 T/A cg26939375 chr7:64535504 NA 0.41 6.48 0.33 3.13e-10 Aortic root size; LIHC cis rs6088590 0.931 rs6088624 chr20:33436852 T/A cg06115741 chr20:33292138 TP53INP2 0.58 7.83 0.39 6.22e-14 Coronary artery disease; LIHC cis rs11785693 0.862 rs11774044 chr8:4988035 C/G cg26367366 chr8:4980734 NA 0.61 6.52 0.33 2.57e-10 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs881375 0.967 rs2416805 chr9:123676482 T/C cg14580859 chr9:123691850 NA 0.37 6.56 0.33 1.95e-10 Rheumatoid arthritis; LIHC cis rs4561483 0.619 rs12597429 chr16:12062396 A/G cg08843971 chr16:11963173 GSPT1 -0.3 -6.15 -0.32 2.22e-9 Testicular germ cell tumor; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg00061764 chr3:67564432 SUCLG2 0.41 6.05 0.31 3.86e-9 Longevity; LIHC cis rs7412746 0.658 rs12405726 chr1:150956128 G/A cg15448220 chr1:150897856 SETDB1 0.45 6.95 0.35 1.88e-11 Melanoma; LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg13126279 chr21:47581558 C21orf56 -0.39 -6.08 -0.31 3.19e-9 Testicular germ cell tumor; LIHC cis rs6570726 0.935 rs367643 chr6:145859602 A/C cg23711669 chr6:146136114 FBXO30 0.56 10.02 0.48 7.09e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs6598955 0.670 rs6598942 chr1:26531034 C/T cg00852783 chr1:26633632 UBXN11 0.47 7.73 0.39 1.19e-13 Obesity-related traits; LIHC cis rs7615952 0.688 rs7624806 chr3:125599074 G/A cg05084668 chr3:125655381 ALG1L -0.55 -8.12 -0.4 8.82e-15 Blood pressure (smoking interaction); LIHC cis rs16958440 0.708 rs62096462 chr18:44625179 C/G cg17192377 chr18:44677553 HDHD2 0.52 6.53 0.33 2.38e-10 Sitting height ratio; LIHC cis rs9534288 0.830 rs1126365 chr13:46633196 T/A cg15192986 chr13:46630673 CPB2 -0.6 -8.87 -0.43 4.25e-17 Blood protein levels; LIHC cis rs273218 1.000 rs156385 chr5:53370749 C/T ch.5.1024479R chr5:53302184 ARL15 0.66 10.65 0.5 4.49e-23 Migraine; LIHC cis rs67311347 0.713 rs9861194 chr3:40309225 C/T cg00656387 chr3:40428638 ENTPD3 0.4 6.34 0.32 7.16e-10 Renal cell carcinoma; LIHC cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg18404041 chr3:52824283 ITIH1 -0.57 -9.59 -0.46 1.93e-19 Bipolar disorder; LIHC cis rs4684776 0.877 rs4684065 chr3:11376559 G/T cg00170343 chr3:11313890 ATG7 0.49 6.7 0.34 8.74e-11 Small vessel stroke; LIHC cis rs921968 0.584 rs2305833 chr2:219305404 G/C cg17980119 chr2:219472607 PLCD4 0.37 6.33 0.32 7.76e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6788895 1.000 rs73008905 chr3:150465435 T/C cg09723797 chr3:150481914 SIAH2 0.87 12.1 0.55 2.6e-28 Breast cancer; LIHC cis rs1728785 1.000 rs1749791 chr16:68572347 C/T cg02972257 chr16:68554789 NA -0.56 -6.45 -0.33 3.89e-10 Ulcerative colitis; LIHC cis rs7959452 0.527 rs4761157 chr12:69780907 A/G cg20891283 chr12:69753455 YEATS4 0.9 19.55 0.73 1.18e-57 Blood protein levels; LIHC cis rs7412746 0.634 rs2124952 chr1:150923774 T/A cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.518 rs2569191 chr5:140013903 C/T cg09824255 chr5:140014002 CD14 0.29 6.22 0.32 1.43e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs796364 1.000 rs281771 chr2:200812202 A/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -9.32 -0.45 1.45e-18 Schizophrenia; LIHC cis rs9430161 0.598 rs34350247 chr1:11034460 A/G cg02454025 chr1:11042201 C1orf127 0.96 18.61 0.71 6.65e-54 Ewing sarcoma; LIHC cis rs28830936 0.966 rs8025714 chr15:42120157 G/C cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.11 -0.31 2.7e-9 Diastolic blood pressure; LIHC cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg20607798 chr8:58055168 NA 0.63 7.95 0.39 2.8e-14 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.680 rs6467843 chr7:139070523 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs1941023 0.568 rs1373064 chr11:60168200 C/T cg08716584 chr11:60157161 MS4A7 -0.36 -8.25 -0.41 3.45e-15 Congenital heart disease (maternal effect); LIHC cis rs11758351 0.660 rs113205297 chr6:26210808 A/C cg16070018 chr6:26224392 HIST1H3E 0.57 7.01 0.35 1.29e-11 Gout;Renal underexcretion gout; LIHC cis rs7845219 0.544 rs34208552 chr8:95908067 C/G cg16049864 chr8:95962084 TP53INP1 -0.44 -6.55 -0.33 2.11e-10 Type 2 diabetes; LIHC cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg24642844 chr7:1081250 C7orf50 -0.95 -9.36 -0.45 1.09e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12960505 0.506 rs67680898 chr18:50961057 C/G cg24270629 chr18:50823537 DCC -0.49 -6.72 -0.34 7.53e-11 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.747 rs6789244 chr3:160866230 A/C cg03342759 chr3:160939853 NMD3 -0.75 -11.81 -0.54 3.03e-27 Morning vs. evening chronotype; LIHC cis rs1371867 0.846 rs1660348 chr8:101315248 A/G cg06636551 chr8:101224915 SPAG1 -0.47 -8.76 -0.43 9.03e-17 Atrioventricular conduction; LIHC cis rs2073300 0.826 rs6083136 chr20:23454188 A/G cg12062639 chr20:23401060 NAPB 0.6 7.12 0.36 6.37e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs926392 0.572 rs6129157 chr20:37672247 G/T cg16355469 chr20:37678765 NA 0.52 8.39 0.41 1.29e-15 Dialysis-related mortality; LIHC trans rs6598955 0.671 rs12142535 chr1:26589698 T/A cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.59 -0.42 3.07e-16 Obesity-related traits; LIHC cis rs2404602 0.716 rs4886817 chr15:76877702 C/T cg03037974 chr15:76606532 NA 0.74 14.45 0.62 2.75e-37 Blood metabolite levels; LIHC cis rs77741769 0.571 rs61946382 chr12:121344574 A/T cg02419362 chr12:121203948 SPPL3 0.35 6.04 0.31 3.91e-9 Mean corpuscular volume; LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.47 -6.66 -0.34 1.07e-10 Lymphocyte counts; LIHC cis rs2710642 0.962 rs7567923 chr2:63085848 C/T cg17519650 chr2:63277830 OTX1 -0.44 -7.21 -0.36 3.57e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs7937890 0.904 rs7484197 chr11:14283654 C/T cg23387056 chr11:14280742 SPON1 -0.46 -6.32 -0.32 8.39e-10 Mitochondrial DNA levels; LIHC cis rs1707322 1.000 rs4606257 chr1:46307268 G/A cg06784218 chr1:46089804 CCDC17 0.38 6.69 0.34 9.01e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs9733 0.596 rs2175615 chr1:150624101 A/G cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs3762637 0.941 rs74467988 chr3:122083140 C/T cg24169773 chr3:122142474 KPNA1 -0.48 -9.35 -0.45 1.21e-18 LDL cholesterol levels; LIHC cis rs7216064 1.000 rs2128792 chr17:65857177 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.55 -7.76 -0.39 9.71e-14 Lymphocyte counts; LIHC cis rs9596863 0.898 rs9596850 chr13:54371713 C/T ch.13.53330881F chr13:54432880 NA 0.43 5.8 0.3 1.53e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs2075371 0.863 rs9641966 chr7:133961205 G/A cg20476274 chr7:133979776 SLC35B4 0.71 9.66 0.46 1.1e-19 Mean platelet volume; LIHC cis rs7107174 1.000 rs2510032 chr11:77968631 G/C cg02023728 chr11:77925099 USP35 0.5 9.57 0.46 2.23e-19 Testicular germ cell tumor; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg13711851 chr9:124080947 GSN -0.37 -6.12 -0.31 2.59e-9 Calcium levels; LIHC cis rs6570726 0.738 rs6917199 chr6:145918320 G/A cg23711669 chr6:146136114 FBXO30 0.73 12.24 0.55 8.07e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.48 -6.91 -0.35 2.38e-11 Prostate cancer; LIHC cis rs4843747 0.708 rs11866437 chr16:88072279 A/G cg07527105 chr16:88053339 BANP 0.4 5.72 0.3 2.28e-8 Menopause (age at onset); LIHC cis rs10508774 1.000 rs72782234 chr10:32935433 G/T cg01819863 chr10:32635814 EPC1 0.64 5.94 0.31 6.88e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs11758351 0.866 rs56186759 chr6:26207181 C/T cg23601095 chr6:26197514 HIST1H3D 0.54 5.79 0.3 1.58e-8 Gout;Renal underexcretion gout; LIHC cis rs9420 0.922 rs35808061 chr11:57547000 T/C cg19752551 chr11:57585705 CTNND1 -0.51 -7.08 -0.36 8.46e-12 Schizophrenia; LIHC cis rs1144333 1.000 rs60144605 chr1:76359699 A/C cg10523679 chr1:76189770 ACADM 0.47 6.69 0.34 9.36e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg22800045 chr5:56110881 MAP3K1 0.68 8.74 0.43 1.03e-16 Initial pursuit acceleration; LIHC cis rs918629 0.530 rs967546 chr5:95232551 G/A cg10483112 chr5:95245456 ELL2 -0.35 -6.4 -0.33 5.21e-10 IgG glycosylation; LIHC cis rs12477438 0.520 rs13031919 chr2:99848932 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.6 9.31 0.45 1.58e-18 Chronic sinus infection; LIHC cis rs8027181 1.000 rs12900863 chr15:73094671 C/T cg25632853 chr15:73088954 NA 0.37 6.26 0.32 1.19e-9 Triglyceride levels; LIHC cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg12379764 chr21:47803548 PCNT 0.57 8.57 0.42 3.65e-16 Testicular germ cell tumor; LIHC cis rs7772486 0.686 rs9403739 chr6:146015357 A/G cg13319975 chr6:146136371 FBXO30 0.41 6.47 0.33 3.39e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs13161895 1.000 rs35973843 chr5:179466502 T/C cg06664874 chr5:179499304 RNF130 0.61 7.56 0.38 3.66e-13 LDL cholesterol; LIHC cis rs6502050 0.698 rs36043222 chr17:80117822 G/T cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg16145915 chr7:1198662 ZFAND2A -0.42 -11.48 -0.53 4.85e-26 Longevity;Endometriosis; LIHC cis rs1008375 1.000 rs10019856 chr4:17615742 T/A cg02297831 chr4:17616191 MED28 0.51 7.83 0.39 6.04e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11626933 0.851 rs2282031 chr14:90730943 A/G cg14092571 chr14:90743983 NA -0.64 -10.78 -0.5 1.64e-23 Gut microbiota (bacterial taxa); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07495314 chr13:27845355 RASL11A -0.51 -6.25 -0.32 1.19e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4843747 0.671 rs9921236 chr16:88117015 G/T cg00677901 chr16:88017247 BANP 0.52 7.99 0.4 2.11e-14 Menopause (age at onset); LIHC cis rs7116495 1.000 rs7113549 chr11:71829967 T/C cg26138937 chr11:71823887 C11orf51 0.71 7.3 0.37 2.08e-12 Severe influenza A (H1N1) infection; LIHC cis rs2067615 0.579 rs10778506 chr12:107143260 T/C cg15890332 chr12:107067104 RFX4 0.26 6.13 0.31 2.38e-9 Heart rate; LIHC cis rs4660306 0.677 rs781059 chr1:45934562 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.63 -6.81 -0.35 4.3e-11 Homocysteine levels; LIHC cis rs2153535 0.580 rs7767756 chr6:8453428 A/C cg07606381 chr6:8435919 SLC35B3 0.8 12.02 0.55 5.26e-28 Motion sickness; LIHC cis rs6840360 0.554 rs13108359 chr4:152727852 T/C cg22705602 chr4:152727874 NA 0.41 8.65 0.42 2.02e-16 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg20607798 chr8:58055168 NA 0.47 5.89 0.3 9.13e-9 Developmental language disorder (linguistic errors); LIHC trans rs1499614 0.803 rs1922723 chr7:66175063 C/T cg10756647 chr7:56101905 PSPH 0.99 11.92 0.54 1.2e-27 Gout; LIHC cis rs2073499 0.935 rs28365992 chr3:50340996 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.71 8.12 0.4 8.55e-15 Schizophrenia; LIHC cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg03264133 chr6:25882463 NA -0.74 -9.36 -0.45 1.07e-18 Intelligence (multi-trait analysis); LIHC cis rs61041384 0.661 rs75589918 chr12:123594402 G/C cg25930673 chr12:123319894 HIP1R 0.66 6.26 0.32 1.18e-9 Schizophrenia; LIHC cis rs1023500 1.000 rs6002548 chr22:42337040 T/G cg04733989 chr22:42467013 NAGA -0.51 -6.03 -0.31 4.34e-9 Schizophrenia; LIHC cis rs910316 0.934 rs8016330 chr14:75657507 G/T cg08847533 chr14:75593920 NEK9 -0.8 -16.25 -0.66 2.1e-44 Height; LIHC cis rs912057 1.000 rs912057 chr6:6736931 C/T cg06612196 chr6:6737390 NA -0.5 -9.26 -0.45 2.35e-18 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs2228479 0.850 rs62054640 chr16:89823157 C/T cg00800038 chr16:89945340 TCF25 -0.6 -8.82 -0.43 5.89e-17 Skin colour saturation; LIHC trans rs61931739 0.534 rs1852222 chr12:34008665 C/A cg26384229 chr12:38710491 ALG10B 0.43 6.13 0.31 2.47e-9 Morning vs. evening chronotype; LIHC cis rs9303401 0.659 rs35539277 chr17:56853833 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.99 13.91 0.6 3.56e-35 Cognitive test performance; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.71 11.61 0.53 1.76e-26 Prudent dietary pattern; LIHC cis rs17854409 0.881 rs68091818 chr20:61479882 A/C cg05147244 chr20:61493195 TCFL5 1.17 10.98 0.51 3.04e-24 Obesity-related traits; LIHC cis rs11674184 0.659 rs59129126 chr2:11728388 T/C cg07314298 chr2:11723111 GREB1 -0.65 -12.37 -0.56 2.67e-29 Endometriosis; LIHC cis rs9303280 0.868 rs11650661 chr17:38026286 A/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.82 0.3 1.33e-8 Self-reported allergy; LIHC cis rs4919694 1.000 rs78893207 chr10:104796138 T/C cg04362960 chr10:104952993 NT5C2 1.15 9.06 0.44 1.04e-17 Arsenic metabolism; LIHC cis rs2115630 0.645 rs4842978 chr15:85197253 T/C cg11189052 chr15:85197271 WDR73 -0.53 -8.12 -0.4 8.52e-15 P wave terminal force; LIHC cis rs1005277 0.540 rs4934907 chr10:38015230 A/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.61 -0.46 1.65e-19 Extrinsic epigenetic age acceleration; LIHC cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg12463550 chr7:65579703 CRCP 0.68 7.04 0.36 1.03e-11 Diabetic kidney disease; LIHC cis rs2070433 0.800 rs2073380 chr21:47863757 A/C cg12379764 chr21:47803548 PCNT 0.71 10.13 0.48 3e-21 Lymphocyte counts; LIHC cis rs400736 0.602 rs10864330 chr1:8168564 C/T cg25007680 chr1:8021821 PARK7 -0.53 -8.01 -0.4 1.82e-14 Response to antidepressants and depression; LIHC cis rs4788570 0.566 rs3886947 chr16:71483958 G/C cg06353428 chr16:71660113 MARVELD3 -1.13 -10.17 -0.48 2.17e-21 Intelligence (multi-trait analysis); LIHC cis rs2380220 0.808 rs2613551 chr6:95914740 G/A cg15832292 chr6:96025679 MANEA -0.62 -7.02 -0.35 1.2e-11 Behavioural disinhibition (generation interaction); LIHC cis rs6840360 0.571 rs4696101 chr4:152528513 A/G cg22705602 chr4:152727874 NA -0.33 -6.27 -0.32 1.08e-9 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg11764359 chr7:65958608 NA 0.57 6.02 0.31 4.62e-9 Diabetic kidney disease; LIHC cis rs7131987 0.903 rs11050161 chr12:29420049 A/G cg21522988 chr12:29376872 FAR2 0.28 6.38 0.33 5.81e-10 QT interval; LIHC cis rs951366 0.764 rs708725 chr1:205744138 G/T cg24503407 chr1:205819492 PM20D1 0.71 10.17 0.48 2.1e-21 Menarche (age at onset); LIHC cis rs8192917 1.000 rs8192917 chr14:25102160 C/T cg03875678 chr14:25103546 GZMB -0.42 -7.7 -0.38 1.49e-13 Vitiligo; LIHC cis rs13118159 0.801 rs7664474 chr4:1329116 T/A cg19318889 chr4:1322082 MAEA 0.45 6.94 0.35 1.93e-11 Longevity; LIHC cis rs477692 1.000 rs522891 chr10:131430916 T/C cg19680672 chr10:131412579 MGMT 0.46 6.99 0.35 1.48e-11 Response to temozolomide; LIHC cis rs8038465 0.622 rs56712926 chr15:73886849 G/T cg15420318 chr15:73925796 NPTN 0.49 7.21 0.36 3.55e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7296418 0.961 rs7957096 chr12:123544878 A/G cg06742321 chr12:123595122 PITPNM2 0.31 5.83 0.3 1.32e-8 Platelet count; LIHC cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg06873352 chr17:61820015 STRADA -0.51 -7.7 -0.38 1.45e-13 Height; LIHC cis rs7072216 0.763 rs10748729 chr10:100171371 G/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs2073499 1.000 rs57319506 chr3:50285677 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.74 7.8 0.39 7.8e-14 Schizophrenia; LIHC cis rs4423214 0.592 rs11233933 chr11:71210070 C/T cg05163923 chr11:71159392 DHCR7 -0.63 -7.62 -0.38 2.52e-13 Vitamin D levels; LIHC cis rs17106184 1.000 rs58574309 chr1:50960180 C/T cg07174182 chr1:51127561 FAF1 -0.64 -7.07 -0.36 8.74e-12 Type 2 diabetes; LIHC cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg22800045 chr5:56110881 MAP3K1 0.69 8.96 0.44 2.15e-17 Initial pursuit acceleration; LIHC cis rs4065321 0.522 rs34648856 chr17:38149411 G/A cg17467752 chr17:38218738 THRA -0.5 -8.46 -0.42 7.76e-16 White blood cell count (basophil);White blood cell count; LIHC cis rs6456156 0.565 rs12529959 chr6:167469292 T/C cg12798992 chr6:167411361 FGFR1OP 0.44 6.85 0.35 3.44e-11 Primary biliary cholangitis; LIHC cis rs6964587 0.869 rs7778667 chr7:91520816 C/G cg17063962 chr7:91808500 NA -0.98 -18.28 -0.7 1.42e-52 Breast cancer; LIHC trans rs2727020 0.587 rs1164658 chr11:49298551 C/A cg15704280 chr7:45808275 SEPT13 0.9 16.63 0.67 6.04e-46 Coronary artery disease; LIHC cis rs11229555 0.645 rs4517537 chr11:58213695 G/A cg15696309 chr11:58395628 NA -0.65 -7.64 -0.38 2.25e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9611519 0.780 rs9611527 chr22:41644428 G/A cg03806693 chr22:41940476 POLR3H -0.68 -8.21 -0.41 4.63e-15 Neuroticism; LIHC cis rs807029 0.577 rs3740490 chr10:102756743 G/C cg25179470 chr10:102756915 LZTS2 0.45 6.23 0.32 1.36e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs3749237 0.595 rs4855859 chr3:49526300 C/T cg07636037 chr3:49044803 WDR6 0.56 8.46 0.42 7.75e-16 Resting heart rate; LIHC cis rs4638749 0.677 rs12712014 chr2:108812044 A/G cg06795125 chr2:108905320 SULT1C2 0.3 6.13 0.31 2.38e-9 Blood pressure; LIHC cis rs7212590 0.748 rs59685433 chr17:57891207 T/C cg10252138 chr17:58120427 NA -0.62 -6.11 -0.31 2.66e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs28530618 0.580 rs11167174 chr20:31248879 G/A cg13636640 chr20:31349939 DNMT3B -0.42 -5.78 -0.3 1.66e-8 Birth weight; LIHC cis rs7116495 1.000 rs10128658 chr11:71733519 C/T cg26138937 chr11:71823887 C11orf51 -0.83 -8.45 -0.42 8.57e-16 Severe influenza A (H1N1) infection; LIHC cis rs225245 0.782 rs321601 chr17:33892087 A/C cg05299278 chr17:33885742 SLFN14 -0.21 -5.84 -0.3 1.2e-8 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs17125944 0.505 rs3783447 chr14:53191647 G/A cg00686598 chr14:53173677 PSMC6 1.23 15.9 0.65 5.11e-43 Alzheimer's disease (late onset); LIHC trans rs12780046 0.656 rs1578708 chr10:100827319 T/C cg05980083 chr9:112191166 PTPN3 -0.46 -6.06 -0.31 3.63e-9 Non-glioblastoma glioma; LIHC cis rs888194 0.738 rs7311187 chr12:109937907 C/T cg05360138 chr12:110035743 NA 0.4 5.74 0.3 2.07e-8 Neuroticism; LIHC trans rs875971 1.000 rs709595 chr7:65817333 G/C cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs1005277 0.557 rs176887 chr10:38406094 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2932538 0.922 rs12750621 chr1:113206502 G/C cg22162597 chr1:113214053 CAPZA1 0.74 9.87 0.47 2.19e-20 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs875971 1.000 rs6957199 chr7:65978519 T/C cg18876405 chr7:65276391 NA 0.37 6.75 0.34 6.39e-11 Aortic root size; LIHC cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg23758822 chr17:41437982 NA 0.94 17.49 0.69 2.15e-49 Menopause (age at onset); LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/T cg23043544 chr7:2124092 MAD1L1 -0.94 -9.01 -0.44 1.45e-17 Bipolar disorder and schizophrenia; LIHC cis rs7572733 0.555 rs7590828 chr2:198940251 A/G cg03934865 chr2:198174659 NA -0.43 -6.27 -0.32 1.12e-9 Dermatomyositis; LIHC cis rs5769765 0.874 rs4624 chr22:50281917 A/G cg26441486 chr22:50317300 CRELD2 -0.35 -6.32 -0.32 7.96e-10 Schizophrenia; LIHC cis rs34172651 0.517 rs8059004 chr16:24837905 G/A cg00339695 chr16:24857497 SLC5A11 0.73 10.78 0.5 1.65e-23 Intelligence (multi-trait analysis); LIHC cis rs16854884 0.632 rs62267390 chr3:143644067 A/T cg06585982 chr3:143692056 C3orf58 0.63 8.77 0.43 8.72e-17 Economic and political preferences (feminism/equality); LIHC cis rs2836950 0.520 rs11911087 chr21:40665192 G/A cg11890956 chr21:40555474 PSMG1 -0.43 -6.95 -0.35 1.81e-11 Menarche (age at onset); LIHC cis rs11098499 0.754 rs10213267 chr4:120239074 A/G cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg12310025 chr6:25882481 NA -0.39 -6.03 -0.31 4.33e-9 Height; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.48 0.56 1.06e-29 Prudent dietary pattern; LIHC cis rs736408 0.924 rs2535629 chr3:52833219 C/T cg11645453 chr3:52864694 ITIH4 0.22 6.22 0.32 1.44e-9 Bipolar disorder; LIHC cis rs801193 1.000 rs3800812 chr7:66223461 T/C cg14393609 chr7:65229607 NA 0.37 5.72 0.3 2.3e-8 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04226401 chr1:100818170 CDC14A 0.47 6.58 0.34 1.79e-10 Lung function (FEV1/FVC); LIHC cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg05564831 chr3:52568323 NT5DC2 -0.37 -5.92 -0.3 7.97e-9 Bipolar disorder; LIHC cis rs2153535 0.580 rs9406162 chr6:8466196 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.02 0.4 1.65e-14 Motion sickness; LIHC cis rs922107 0.688 rs10922661 chr1:90024094 T/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.7 -0.38 1.49e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs11585357 0.793 rs11588418 chr1:17616445 A/G cg08277548 chr1:17600880 PADI3 -0.58 -6.05 -0.31 3.88e-9 Hair shape; LIHC cis rs8141529 0.871 rs5762877 chr22:29277555 G/A cg02153584 chr22:29168773 CCDC117 0.53 8.18 0.4 5.75e-15 Lymphocyte counts; LIHC cis rs10276381 1.000 rs10263857 chr7:28187284 C/G cg23620719 chr7:28220237 JAZF1 0.63 7.82 0.39 6.43e-14 Crohn's disease; LIHC cis rs10484885 0.763 rs56401039 chr6:90522486 C/T cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.69 -0.34 8.94e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9733 0.744 rs11204725 chr1:150742700 T/C cg13175981 chr1:150552382 MCL1 0.48 7.05 0.36 1.01e-11 Tonsillectomy; LIHC cis rs1707322 0.963 rs11211202 chr1:46292382 C/T cg06784218 chr1:46089804 CCDC17 0.35 6.34 0.32 7.11e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs473651 0.935 rs482775 chr2:239335403 G/C cg21699342 chr2:239360505 ASB1 0.36 6.92 0.35 2.24e-11 Multiple system atrophy; LIHC cis rs2576037 0.526 rs10853545 chr18:44475220 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 10.24 0.48 1.2e-21 Personality dimensions; LIHC cis rs2370759 1.000 rs2225152 chr10:32574759 T/C cg01819863 chr10:32635814 EPC1 1.11 16.42 0.66 4.34e-45 Sexual dysfunction (female); LIHC cis rs4689592 0.554 rs66925245 chr4:7071999 C/T cg02503808 chr4:7069936 GRPEL1 -0.79 -10.82 -0.5 1.19e-23 Monocyte percentage of white cells; LIHC cis rs2153535 0.580 rs7450817 chr6:8481421 G/A cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC trans rs208520 0.802 rs208496 chr6:66930786 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.11 -0.4 9.32e-15 Exhaled nitric oxide output; LIHC cis rs79149102 0.579 rs7163390 chr15:75280426 T/C cg16226627 chr15:75307476 SCAMP5 0.54 10.05 0.48 5.36e-21 Lung cancer; LIHC cis rs6430585 0.528 rs16832440 chr2:136754183 G/A cg07305463 chr2:136567211 LCT -0.38 -5.85 -0.3 1.17e-8 Corneal structure; LIHC cis rs986417 0.892 rs8010656 chr14:60797112 G/A cg27398547 chr14:60952738 C14orf39 -0.73 -7.45 -0.37 7.7e-13 Gut microbiota (bacterial taxa); LIHC cis rs2303759 0.918 rs10405465 chr19:49869298 C/T cg24324837 chr19:49891574 CCDC155 0.38 6.01 0.31 4.64e-9 Multiple sclerosis; LIHC cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg27286337 chr10:134555280 INPP5A 0.87 12.52 0.56 7.35e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9733 0.596 rs12089989 chr1:150715782 G/A cg15448220 chr1:150897856 SETDB1 0.36 5.75 0.3 1.96e-8 Tonsillectomy; LIHC cis rs1577917 0.917 rs1584273 chr6:86524577 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs3892630 0.500 rs6510301 chr19:33359791 A/T cg22980127 chr19:33182716 NUDT19 0.82 9.56 0.46 2.33e-19 Red blood cell traits; LIHC cis rs4474465 0.833 rs6592792 chr11:78271614 A/C cg27205649 chr11:78285834 NARS2 0.44 6.37 0.33 6.27e-10 Alzheimer's disease (survival time); LIHC cis rs6912958 0.754 rs10755484 chr6:88244648 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -8.07 -0.4 1.19e-14 Monocyte percentage of white cells; LIHC cis rs950169 0.580 rs11634320 chr15:85172183 A/C cg17507749 chr15:85114479 UBE2QP1 -0.69 -8.02 -0.4 1.68e-14 Schizophrenia; LIHC cis rs2239547 0.522 rs6773040 chr3:52935428 C/A cg11645453 chr3:52864694 ITIH4 -0.31 -7.88 -0.39 4.49e-14 Schizophrenia; LIHC cis rs208520 0.770 rs2153941 chr6:66885521 A/T cg07460842 chr6:66804631 NA -0.76 -8.34 -0.41 1.89e-15 Exhaled nitric oxide output; LIHC cis rs11864453 0.826 rs12708928 chr16:72137227 C/A cg01557791 chr16:72042693 DHODH -0.56 -9.11 -0.44 7.06e-18 Fibrinogen levels; LIHC cis rs11958404 0.929 rs60700182 chr5:157438376 A/G cg05962755 chr5:157440814 NA 0.99 11.5 0.53 4.32e-26 IgG glycosylation; LIHC cis rs7772486 0.719 rs2206141 chr6:146086192 A/G cg13319975 chr6:146136371 FBXO30 0.41 6.66 0.34 1.08e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2075371 1.000 rs2504 chr7:133979545 A/T cg20476274 chr7:133979776 SLC35B4 0.76 13.03 0.58 8.94e-32 Mean platelet volume; LIHC trans rs1814175 0.817 rs7481230 chr11:49772235 G/A cg15704280 chr7:45808275 SEPT13 -1.02 -23.29 -0.78 1.49e-72 Height; LIHC cis rs738322 0.555 rs5750547 chr22:38546700 A/G cg25457927 chr22:38595422 NA 0.35 8.5 0.42 5.99e-16 Cutaneous nevi; LIHC cis rs7568498 0.564 rs10490563 chr2:161914168 G/A cg22496339 chr2:162101262 NA -0.52 -7.07 -0.36 8.57e-12 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy); LIHC cis rs1707322 0.929 rs785513 chr1:46538320 T/C cg03146154 chr1:46216737 IPP -0.46 -7.46 -0.37 7.03e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7668874 0.581 rs55845194 chr4:116741283 T/C cg08917878 chr5:172668965 NA -0.3 -6.1 -0.31 2.87e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs72781680 0.898 rs55846516 chr2:24158003 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.77 0.39 9.29e-14 Lymphocyte counts; LIHC cis rs3741404 0.560 rs12362602 chr11:63908660 G/A cg18225595 chr11:63971243 STIP1 -0.6 -9.39 -0.45 8.6e-19 Platelet count; LIHC cis rs6502050 0.799 rs6502078 chr17:80124364 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs1055129 0.682 rs7217432 chr17:73834604 A/G cg19302996 chr17:73780495 UNK -0.6 -9.49 -0.46 4e-19 White matter hyperintensity burden; LIHC cis rs763121 0.853 rs5750621 chr22:38956166 C/T cg14440974 chr22:39074834 NA -0.44 -7.01 -0.35 1.27e-11 Menopause (age at onset); LIHC cis rs703842 0.575 rs701006 chr12:58106836 C/T cg18357645 chr12:58087776 OS9 -0.49 -8.36 -0.41 1.64e-15 Multiple sclerosis; LIHC cis rs4934494 0.768 rs34663515 chr10:91392543 C/G cg19698084 chr10:91461284 KIF20B -0.48 -6.61 -0.34 1.5e-10 Red blood cell count; LIHC cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg08219700 chr8:58056026 NA 0.52 7.14 0.36 5.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.882 rs35056669 chr3:10014171 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.56 -0.5 9.42e-23 Alzheimer's disease; LIHC cis rs6762 0.748 rs28551040 chr11:840740 G/A cg15787769 chr11:842744 TSPAN4;POLR2L -0.66 -7.78 -0.39 8.93e-14 Mean platelet volume; LIHC cis rs11677370 0.533 rs12711971 chr2:3820821 G/C cg17052675 chr2:3827356 NA -0.55 -7.36 -0.37 1.39e-12 Type 2 diabetes; LIHC cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.26 -0.61 1.62e-36 Alzheimer's disease; LIHC cis rs17445774 0.857 rs6435043 chr2:200900974 C/G cg23649088 chr2:200775458 C2orf69 0.67 7.67 0.38 1.78e-13 LDL cholesterol to HDL cholesterol ratio; LIHC cis rs6570726 0.846 rs7773939 chr6:145927384 C/T cg23711669 chr6:146136114 FBXO30 -0.67 -11.23 -0.52 4.11e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.45 7.47 0.37 6.68e-13 Height; LIHC cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg02353165 chr6:42928485 GNMT 0.93 14.52 0.62 1.45e-37 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs2243480 1.000 rs6949812 chr7:65387101 G/A cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs7091068 0.566 rs7909925 chr10:95507170 A/G cg20715218 chr10:95462985 C10orf4 0.56 5.84 0.3 1.2e-8 Urinary tract infection frequency; LIHC trans rs9951602 0.573 rs8098953 chr18:76648734 A/G cg02800362 chr5:177631904 HNRNPAB 0.67 10.71 0.5 2.88e-23 Obesity-related traits; LIHC cis rs4332037 0.722 rs28705934 chr7:1916116 T/A cg23043544 chr7:2124092 MAD1L1 -0.42 -6.33 -0.32 7.9e-10 Bipolar disorder; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg14828511 chr1:107599125 PRMT6 -0.41 -5.8 -0.3 1.53e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs332507 0.830 rs333355 chr3:124393595 A/G cg05980111 chr3:124395277 KALRN 0.45 6.94 0.35 2.03e-11 Plateletcrit; LIHC cis rs17125944 0.615 rs8003334 chr14:53374967 C/T cg00686598 chr14:53173677 PSMC6 0.86 9.32 0.45 1.43e-18 Alzheimer's disease (late onset); LIHC trans rs4843747 0.671 rs9921236 chr16:88117015 G/T cg26811252 chr16:29126840 RRN3P2 0.43 7.08 0.36 8.25e-12 Menopause (age at onset); LIHC cis rs10503871 0.725 rs7017861 chr8:30373040 G/A cg26383811 chr8:30366931 RBPMS 0.43 7.5 0.38 5.38e-13 Metabolite levels (X-11787); LIHC cis rs708547 0.830 rs1713983 chr4:57883084 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.6 8.49 0.42 6.53e-16 Response to bleomycin (chromatid breaks); LIHC cis rs8072100 1.000 rs4794048 chr17:45763073 A/C cg19378624 chr17:45501242 LOC100272146;C17orf57 -0.37 -5.88 -0.3 9.9e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs1799949 0.965 rs2236762 chr17:41226675 A/T cg05368731 chr17:41323189 NBR1 0.68 11.53 0.53 3.45e-26 Menopause (age at onset); LIHC cis rs801193 1.000 rs10274773 chr7:66133578 G/A cg00343986 chr7:65444356 GUSB -0.39 -5.84 -0.3 1.2e-8 Aortic root size; LIHC cis rs3806843 1.000 rs1548700 chr5:140164889 A/T cg19875535 chr5:140030758 IK 0.36 5.95 0.31 6.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1816752 0.870 rs7320102 chr13:25011573 T/C cg22771759 chr13:24902376 NA 0.32 6.8 0.35 4.62e-11 Obesity-related traits; LIHC cis rs763121 0.815 rs4821799 chr22:39021326 T/G cg06544989 chr22:39130855 UNC84B 0.36 6.07 0.31 3.34e-9 Menopause (age at onset); LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.42 -6.38 -0.33 5.62e-10 Menopause (age at onset); LIHC cis rs7095607 0.606 rs7095492 chr10:69957375 C/T cg18986048 chr10:69913749 MYPN 0.39 5.88 0.3 9.94e-9 Lung function (FVC); LIHC cis rs2777491 0.874 rs13379756 chr15:41663896 A/C cg18705301 chr15:41695430 NDUFAF1 -0.58 -8.77 -0.43 8.31e-17 Ulcerative colitis; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg19846264 chr17:4125408 ANKFY1 0.4 6.17 0.32 1.9e-9 Immature fraction of reticulocytes; LIHC cis rs763121 0.853 rs5750630 chr22:38985818 A/C cg21395723 chr22:39101663 GTPBP1 0.37 5.77 0.3 1.82e-8 Menopause (age at onset); LIHC cis rs2625529 0.824 rs11072346 chr15:72400434 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.86 -0.3 1.06e-8 Red blood cell count; LIHC cis rs2607426 1.000 rs2279699 chr19:41284398 G/A cg20631044 chr19:41255890 C19orf54;SNRPA -0.5 -5.78 -0.3 1.71e-8 Blood protein levels; LIHC cis rs72781680 0.752 rs56343114 chr2:23900629 C/G cg08917208 chr2:24149416 ATAD2B 0.85 7.49 0.38 5.93e-13 Lymphocyte counts; LIHC cis rs7927771 0.965 rs12787112 chr11:47687147 A/G cg20135002 chr11:47629003 NA -0.56 -9.64 -0.46 1.35e-19 Subjective well-being; LIHC cis rs9814567 1.000 rs6439484 chr3:134249899 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9612 0.718 rs346522 chr19:44262545 C/T cg08581076 chr19:44259116 C19orf61 -0.62 -8.2 -0.41 4.9e-15 Exhaled nitric oxide output; LIHC cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg27286337 chr10:134555280 INPP5A 0.88 13.19 0.58 2.03e-32 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18942022 chr15:59949764 GTF2A2 -0.62 -7.51 -0.38 5.2e-13 Systolic blood pressure; LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs10193935 0.901 rs3755304 chr2:42589921 A/G cg27598129 chr2:42591480 NA 0.76 11.93 0.54 1.12e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs801193 1.000 rs6975195 chr7:66124774 T/A cg00343986 chr7:65444356 GUSB -0.4 -5.87 -0.3 1.05e-8 Aortic root size; LIHC cis rs7772486 0.790 rs6917135 chr6:146152426 T/C cg13319975 chr6:146136371 FBXO30 -0.34 -5.78 -0.3 1.7e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg07677032 chr17:61819896 STRADA 0.43 6.22 0.32 1.43e-9 Prudent dietary pattern; LIHC cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg09367891 chr1:107599246 PRMT6 0.71 11.91 0.54 1.33e-27 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg11647651 chr17:4710373 PLD2 -0.56 -6.41 -0.33 4.79e-10 Systolic blood pressure; LIHC trans rs1814175 0.564 rs12416819 chr11:49755567 T/C cg03929089 chr4:120376271 NA -0.85 -16.54 -0.67 1.44e-45 Height; LIHC cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg24209194 chr3:40518798 ZNF619 0.52 7.73 0.39 1.17e-13 Renal cell carcinoma; LIHC cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg08499158 chr17:42289980 UBTF -0.51 -8.28 -0.41 2.82e-15 Total body bone mineral density; LIHC cis rs7945718 0.591 rs7926971 chr11:12698040 A/G cg25843174 chr11:12811716 TEAD1 0.34 7.92 0.39 3.42e-14 Educational attainment (years of education); LIHC cis rs6964587 1.000 rs10263309 chr7:91645265 A/G cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs1552244 0.882 rs13100734 chr3:10022878 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.62 -9.57 -0.46 2.16e-19 Alzheimer's disease; LIHC cis rs2073300 0.609 rs6132617 chr20:23420151 G/C cg16736954 chr20:23401023 NAPB 0.69 8.11 0.4 9.04e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs7726839 0.540 rs72705030 chr5:645562 C/T cg25482853 chr8:67687455 SGK3 0.61 6.14 0.32 2.31e-9 Obesity-related traits; LIHC cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs6598955 0.671 rs12085416 chr1:26627835 T/C cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.23 -0.41 3.96e-15 Obesity-related traits; LIHC cis rs1568889 0.775 rs35243076 chr11:28250618 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.11 0.61 5.84e-36 Bipolar disorder; LIHC cis rs9910055 0.529 rs850851 chr17:42177674 C/T cg19774624 chr17:42201019 HDAC5 0.49 6.03 0.31 4.14e-9 Total body bone mineral density; LIHC trans rs10506458 0.834 rs17738403 chr12:63389200 A/G cg22491629 chr6:157744540 C6orf35 -0.61 -10.92 -0.51 4.95e-24 Hemostatic factors and hematological phenotypes; LIHC trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg26668828 chr6:292823 DUSP22 -0.65 -9.25 -0.45 2.49e-18 Menopause (age at onset); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg13240253 chr3:71245529 FOXP1 0.35 6.14 0.32 2.23e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs1707322 1.000 rs4660328 chr1:46444831 G/T cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs8016982 0.610 rs2371570 chr14:81709686 C/T cg01989461 chr14:81687754 GTF2A1 0.72 14.54 0.62 1.2e-37 Schizophrenia; LIHC trans rs875971 0.577 rs34888281 chr7:65585771 C/T cg26939375 chr7:64535504 NA -0.47 -6.89 -0.35 2.73e-11 Aortic root size; LIHC cis rs2479724 0.846 rs1536702 chr6:41869950 T/A cg17623882 chr6:41773611 USP49 -0.55 -8.65 -0.42 2e-16 Menarche (age at onset); LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg06873352 chr17:61820015 STRADA 0.74 13.45 0.59 2.07e-33 Prudent dietary pattern; LIHC cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg05564831 chr3:52568323 NT5DC2 0.35 5.86 0.3 1.09e-8 Bipolar disorder; LIHC cis rs6429082 0.764 rs291377 chr1:235695186 C/T cg26050004 chr1:235667680 B3GALNT2 -0.43 -6.69 -0.34 9.15e-11 Adiposity; LIHC cis rs6912958 1.000 rs9294380 chr6:88152667 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.4 -7.1 -0.36 7.42e-12 Monocyte percentage of white cells; LIHC cis rs8081395 0.741 rs180519 chr17:58016271 G/A cg02344993 chr17:57696989 CLTC 0.35 5.72 0.3 2.3e-8 White blood cell count; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg21448741 chr8:58168803 NA 0.36 6.72 0.34 7.69e-11 Developmental language disorder (linguistic errors); LIHC cis rs2228479 0.850 rs11645916 chr16:89835234 G/A cg06558623 chr16:89946397 TCF25 0.85 11.71 0.53 7.62e-27 Skin colour saturation; LIHC cis rs748404 0.697 rs492743 chr15:43560945 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 6.85 0.35 3.49e-11 Lung cancer; LIHC trans rs6598955 0.671 rs13374173 chr1:26602256 T/G cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs3008870 0.755 rs2755254 chr1:67470855 C/T cg02640540 chr1:67518911 SLC35D1 0.42 6.47 0.33 3.4e-10 Lymphocyte percentage of white cells; LIHC cis rs7927592 0.956 rs11228256 chr11:68251460 G/A cg01657329 chr11:68192670 LRP5 -0.45 -5.9 -0.3 8.7e-9 Total body bone mineral density; LIHC cis rs4665809 0.549 rs3828255 chr2:26413252 G/A cg04944784 chr2:26401820 FAM59B 0.65 6.78 0.34 5.24e-11 Gut microbiome composition (summer); LIHC cis rs2153535 0.580 rs9328488 chr6:8529411 G/C cg23788917 chr6:8435910 SLC35B3 0.63 9.02 0.44 1.37e-17 Motion sickness; LIHC cis rs6692209 1 rs6692209 chr1:152506444 C/T cg20991723 chr1:152506922 NA 0.58 10.37 0.49 4.49e-22 Plantar warts; LIHC cis rs16828019 0.852 rs35992757 chr1:41652862 C/T cg03387723 chr1:41708464 SCMH1 -0.45 -7.23 -0.36 3.13e-12 Intelligence (multi-trait analysis); LIHC cis rs6456156 0.586 rs12528323 chr6:167461645 A/G cg23791538 chr6:167370224 RNASET2 -0.53 -8.42 -0.41 1.04e-15 Primary biliary cholangitis; LIHC cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg14004847 chr7:1930337 MAD1L1 -0.48 -6.9 -0.35 2.55e-11 Bipolar disorder and schizophrenia; LIHC cis rs7618501 0.902 rs7645061 chr3:49868842 C/T cg24110177 chr3:50126178 RBM5 -0.45 -7.05 -0.36 1.01e-11 Intelligence (multi-trait analysis); LIHC cis rs611744 0.934 rs609102 chr8:109227406 A/G cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs1633360 1 rs1633360 chr12:58108052 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.38 -0.33 5.76e-10 Rheumatoid arthritis; LIHC cis rs922107 0.846 rs4486433 chr1:90007316 G/T cg15422784 chr1:90023713 LRRC8B -0.47 -7.37 -0.37 1.28e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7707921 0.957 rs2059891 chr5:81508792 G/C cg15871215 chr5:81402204 ATG10 0.6 5.97 0.31 6.05e-9 Breast cancer; LIHC cis rs317689 0.680 rs315140 chr12:69790780 A/T cg14784868 chr12:69753453 YEATS4 0.66 9.94 0.47 1.25e-20 Response to diuretic therapy; LIHC cis rs10751667 0.666 rs4074235 chr11:977511 C/G cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC cis rs9326248 0.817 rs1242127 chr11:117076564 A/G cg15534755 chr11:117069859 TAGLN -0.37 -6.44 -0.33 4.15e-10 Blood protein levels; LIHC cis rs10193935 0.901 rs3088290 chr2:42578143 A/G cg27598129 chr2:42591480 NA -0.76 -11.81 -0.54 3.13e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs11105298 0.891 rs11105302 chr12:89891366 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 0.62 7.17 0.36 4.79e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs6840360 0.571 rs4696279 chr4:152560449 G/A cg22705602 chr4:152727874 NA -0.32 -6.23 -0.32 1.38e-9 Intelligence (multi-trait analysis); LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.56 -8.05 -0.4 1.37e-14 Lymphocyte counts; LIHC cis rs1801251 1.000 rs283468 chr2:233658309 C/T cg25237894 chr2:233734115 C2orf82 0.58 11.41 0.52 9.35e-26 Coronary artery disease; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg06719495 chr4:83788000 SEC31A 0.33 7.24 0.36 2.93e-12 Oropharynx cancer; LIHC cis rs1816752 0.905 rs7339140 chr13:25011902 A/G cg22771759 chr13:24902376 NA 0.32 6.8 0.35 4.62e-11 Obesity-related traits; LIHC cis rs7249142 0.562 rs2239370 chr19:19292674 T/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.36 -6.12 -0.31 2.56e-9 IgG glycosylation; LIHC cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg02931644 chr1:25747376 RHCE 0.36 7.9 0.39 3.81e-14 Erythrocyte sedimentation rate; LIHC cis rs12701220 0.604 rs34904312 chr7:1135883 G/A cg16145915 chr7:1198662 ZFAND2A -0.35 -7.02 -0.36 1.17e-11 Bronchopulmonary dysplasia; LIHC cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.03 -10.57 -0.5 8.95e-23 Platelet count; LIHC cis rs17685 0.725 rs4476928 chr7:75642107 C/A cg04610667 chr7:75704037 NA 0.33 5.98 0.31 5.53e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1707322 0.656 rs3014210 chr1:46066608 A/G cg03146154 chr1:46216737 IPP -0.56 -9.47 -0.46 4.61e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11098499 0.698 rs4422403 chr4:120258194 C/T cg09307838 chr4:120376055 NA 0.62 9.74 0.47 6e-20 Corneal astigmatism; LIHC cis rs7172677 0.961 rs12102035 chr15:75418871 A/G cg09165964 chr15:75287851 SCAMP5 -0.42 -5.89 -0.3 9.23e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6430585 0.528 rs16832440 chr2:136754183 G/A cg07169764 chr2:136633963 MCM6 1.29 20.96 0.75 2.59e-63 Corneal structure; LIHC cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs9649465 1.000 rs6951138 chr7:123362070 G/A cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.15e-15 Migraine; LIHC cis rs10792665 0.512 rs4280022 chr11:82582615 C/G cg24227371 chr11:82718527 RAB30 -0.27 -6.56 -0.33 1.96e-10 Obesity-related traits; LIHC cis rs10504073 0.647 rs2292399 chr8:49987230 A/G cg00325661 chr8:49890786 NA 0.33 7.64 0.38 2.15e-13 Blood metabolite ratios; LIHC trans rs6419133 0.668 rs7659804 chr4:96301458 C/T cg08466320 chr2:70121048 SNRNP27 -0.55 -6.04 -0.31 3.92e-9 Itch intensity from mosquito bite adjusted by bite size; LIHC trans rs617791 0.530 rs7952056 chr11:65744597 C/T cg17712092 chr4:129076599 LARP1B -0.56 -6.8 -0.35 4.55e-11 Breast cancer; LIHC cis rs1018836 0.632 rs6988302 chr8:91477660 C/T cg16814680 chr8:91681699 NA -0.37 -6.02 -0.31 4.49e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9399135 0.935 rs9376086 chr6:135371329 T/C cg22676075 chr6:135203613 NA 0.41 6.59 0.34 1.66e-10 Red blood cell count; LIHC cis rs2012796 0.743 rs12435764 chr14:81836866 A/C cg02996355 chr14:81879375 NA 0.7 11.49 0.53 4.48e-26 Night sleep phenotypes; LIHC cis rs9916302 0.904 rs11654018 chr17:37703740 C/T cg03013999 chr17:37608204 MED1 -0.35 -5.8 -0.3 1.48e-8 Glomerular filtration rate (creatinine); LIHC cis rs17401966 0.593 rs11121523 chr1:10214442 T/A cg15208524 chr1:10270712 KIF1B 0.44 5.77 0.3 1.74e-8 Hepatocellular carcinoma; LIHC cis rs6912958 0.535 rs1753153 chr6:88032834 T/G cg12350822 chr6:88032061 C6orf162;GJB7 0.38 7.34 0.37 1.55e-12 Monocyte percentage of white cells; LIHC cis rs722599 0.651 rs12887044 chr14:75255659 C/T cg11812906 chr14:75593930 NEK9 0.43 6.51 0.33 2.7e-10 IgG glycosylation; LIHC cis rs11098499 0.754 rs12507565 chr4:120251121 G/A cg09307838 chr4:120376055 NA 0.71 11.25 0.52 3.29e-25 Corneal astigmatism; LIHC cis rs61677309 1.000 rs1945765 chr11:118182829 T/A cg06090739 chr11:118230722 UBE4A 0.35 6.37 0.33 5.97e-10 Lung cancer in ever smokers; LIHC cis rs10751667 0.961 rs7395928 chr11:952605 T/G ch.11.42038R chr11:967971 AP2A2 0.61 11.33 0.52 1.83e-25 Alzheimer's disease (late onset); LIHC cis rs10791097 0.694 rs10791100 chr11:130738946 T/A cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12200782 0.505 rs9295696 chr6:26550288 C/T cg11502198 chr6:26597334 ABT1 0.83 10.57 0.5 8.71e-23 Small cell lung carcinoma; LIHC cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg21724239 chr8:58056113 NA -0.53 -6.59 -0.34 1.71e-10 Developmental language disorder (linguistic errors); LIHC cis rs801193 1.000 rs62466793 chr7:66191517 G/A cg00343986 chr7:65444356 GUSB 0.41 6.1 0.31 2.86e-9 Aortic root size; LIHC cis rs1568889 1.000 rs12796293 chr11:28177723 C/T cg06544937 chr11:28130018 METT5D1;KIF18A -0.53 -7.33 -0.37 1.64e-12 Bipolar disorder; LIHC cis rs116095464 0.558 rs7713524 chr5:276200 C/T cg22496380 chr5:211416 CCDC127 0.93 10.34 0.49 5.33e-22 Breast cancer; LIHC cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg17691542 chr6:26056736 HIST1H1C 0.4 5.93 0.31 7.37e-9 Height; LIHC cis rs208520 0.874 rs208485 chr6:66925654 T/C cg07460842 chr6:66804631 NA -0.72 -7.94 -0.39 2.97e-14 Exhaled nitric oxide output; LIHC cis rs7091068 0.550 rs7079013 chr10:95487878 A/C cg20715218 chr10:95462985 C10orf4 0.59 9.67 0.46 1.06e-19 Urinary tract infection frequency; LIHC cis rs35883536 1.000 rs2297716 chr1:101092526 G/C cg14515779 chr1:101123966 NA -0.67 -13.11 -0.58 4.4e-32 Monocyte count; LIHC cis rs9911578 0.967 rs1267542 chr17:56654690 T/C cg05425664 chr17:57184151 TRIM37 0.58 8.63 0.42 2.41e-16 Intelligence (multi-trait analysis); LIHC cis rs477895 1.000 rs11600990 chr11:64082807 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 7.14 0.36 5.65e-12 Mean platelet volume; LIHC cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg07092213 chr7:1199455 ZFAND2A -0.42 -6.1 -0.31 2.95e-9 Longevity;Endometriosis; LIHC cis rs1395 0.710 rs1992291 chr2:27504312 A/G cg23587288 chr2:27483067 SLC30A3 -0.32 -5.88 -0.3 9.5e-9 Blood metabolite levels; LIHC cis rs8067354 0.645 rs2645492 chr17:57875554 A/G cg02344993 chr17:57696989 CLTC -0.7 -11.76 -0.54 4.75e-27 Hemoglobin concentration; LIHC trans rs875971 0.545 rs1909508 chr7:65766353 G/T cg26939375 chr7:64535504 NA 0.41 6.47 0.33 3.3e-10 Aortic root size; LIHC cis rs7729447 0.776 rs58739438 chr5:32693994 G/C cg16267343 chr5:32710456 NPR3 0.48 5.86 0.3 1.09e-8 Blood pressure; LIHC cis rs385076 0.527 rs10779914 chr2:32106040 C/A cg02381751 chr2:32503542 YIPF4 -0.42 -5.87 -0.3 1.05e-8 Interleukin-18 levels; LIHC cis rs7238033 0.647 rs8095657 chr18:43314545 C/T cg20610511 chr18:43302872 SLC14A1 0.4 6.64 0.34 1.25e-10 Bladder cancer; LIHC cis rs2072499 0.966 rs6427307 chr1:156190083 A/G cg24450063 chr1:156163899 SLC25A44 1.07 18.89 0.71 5.23e-55 Testicular germ cell tumor; LIHC cis rs963731 0.522 rs4670907 chr2:39278066 C/T cg04010122 chr2:39346883 SOS1 -0.71 -6.19 -0.32 1.73e-9 Corticobasal degeneration; LIHC cis rs34330 0.562 rs11055024 chr12:12858969 A/G cg09462578 chr12:12878428 APOLD1 -0.78 -10.41 -0.49 3.09e-22 Systemic lupus erythematosus; LIHC cis rs7592578 0.882 rs2192010 chr2:191462133 C/T cg10560079 chr2:191398806 TMEM194B -0.88 -12.37 -0.56 2.58e-29 Diastolic blood pressure; LIHC cis rs6429082 0.967 rs1305557 chr1:235627837 C/T cg26050004 chr1:235667680 B3GALNT2 0.41 6.45 0.33 3.72e-10 Adiposity; LIHC cis rs74233809 1.000 rs12411886 chr10:104685299 C/A cg03493300 chr10:104813866 CNNM2 0.46 5.96 0.31 6.18e-9 Birth weight; LIHC trans rs1005277 0.557 rs2983338 chr10:38550734 C/T cg04469686 chr1:162760199 HSD17B7 -0.39 -6.04 -0.31 4.11e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7647973 0.667 rs6446286 chr3:49681704 A/G cg03060546 chr3:49711283 APEH 0.61 7.03 0.36 1.09e-11 Menarche (age at onset); LIHC cis rs798554 0.610 rs2527696 chr7:2858315 T/C cg13628971 chr7:2884303 GNA12 0.44 7.01 0.35 1.24e-11 Height; LIHC cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg08645402 chr16:4508243 NA 0.42 7.87 0.39 4.72e-14 Schizophrenia; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg06610675 chr5:60241428 NDUFAF2;ERCC8 -0.43 -6.76 -0.34 5.85e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs911119 1.000 rs1064039 chr20:23618427 C/T cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg22105103 chr4:187893119 NA 0.35 8.93 0.43 2.64e-17 Lobe attachment (rater-scored or self-reported); LIHC trans rs79976124 0.837 rs11751994 chr6:66644028 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.77 0.34 5.54e-11 Type 2 diabetes; LIHC cis rs4819052 0.851 rs2236446 chr21:46678985 T/C cg22633049 chr21:46681294 NA -0.36 -6.35 -0.32 6.69e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs763121 0.853 rs4821798 chr22:39021165 T/C cg06022373 chr22:39101656 GTPBP1 0.75 15.33 0.64 1e-40 Menopause (age at onset); LIHC cis rs8067354 0.540 rs72840315 chr17:58018142 G/C cg13753209 chr17:57696993 CLTC 0.7 10.49 0.49 1.66e-22 Hemoglobin concentration; LIHC cis rs72772090 0.634 rs72773906 chr5:96092274 C/G cg17330273 chr5:96107758 CAST;ERAP1 -0.63 -7.08 -0.36 8.02e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs11671005 0.610 rs2305122 chr19:59056752 G/C cg25952890 chr19:58913133 NA 0.66 6.73 0.34 6.99e-11 Mean platelet volume; LIHC cis rs7044106 0.718 rs1981021 chr9:123388393 T/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.57 0.5 8.87e-23 Hip circumference adjusted for BMI; LIHC cis rs1941023 0.584 rs2241921 chr11:60164302 C/T cg08716584 chr11:60157161 MS4A7 -0.36 -8.26 -0.41 3.31e-15 Congenital heart disease (maternal effect); LIHC cis rs4788570 0.655 rs2133773 chr16:71812296 A/G cg06353428 chr16:71660113 MARVELD3 1.32 12.8 0.57 6.45e-31 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.579 rs1740745 chr10:38520056 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1000083 0.748 rs2643518 chr5:96624096 T/A ch.5.96698337R chr5:96672581 NA 0.96 7.29 0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg18306943 chr3:40428807 ENTPD3 0.35 5.94 0.31 7.05e-9 Renal cell carcinoma; LIHC cis rs35110281 0.782 rs7282933 chr21:45046988 A/G cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.42e-23 Mean corpuscular volume; LIHC cis rs2073300 1.000 rs12626013 chr20:23442215 G/A cg12062639 chr20:23401060 NAPB 0.86 10.33 0.49 6.19e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9911578 1.000 rs1267545 chr17:56646909 A/G cg05425664 chr17:57184151 TRIM37 -0.58 -8.65 -0.42 2.09e-16 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10386016 chr7:103630857 RELN 0.47 6.49 0.33 3.05e-10 Lung function (FEV1/FVC); LIHC cis rs17253792 0.822 rs118027213 chr14:56039076 T/C cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs6964587 0.967 rs28615927 chr7:91600648 C/A cg17063962 chr7:91808500 NA 1.01 19.32 0.72 9.73e-57 Breast cancer; LIHC cis rs2806561 0.734 rs2235548 chr1:23394062 G/A cg12483005 chr1:23474871 LUZP1 0.46 6.92 0.35 2.21e-11 Height; LIHC cis rs651907 0.557 rs13099674 chr3:101489629 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.93 0.51 4.56e-24 Colorectal cancer; LIHC cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg24531977 chr5:56204891 C5orf35 -0.59 -8.35 -0.41 1.73e-15 Initial pursuit acceleration; LIHC cis rs13064411 0.696 rs869343 chr3:113226705 C/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.32 -0.32 8.06e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs11098499 0.863 rs11098531 chr4:120465001 G/A cg09307838 chr4:120376055 NA 0.76 11.71 0.54 7.22e-27 Corneal astigmatism; LIHC cis rs6582630 0.519 rs11514056 chr12:38284001 G/T cg26384229 chr12:38710491 ALG10B 0.81 10.37 0.49 4.17e-22 Drug-induced liver injury (flucloxacillin); LIHC cis rs992157 0.767 rs2382822 chr2:219173327 T/C cg20019365 chr2:219134978 PNKD;AAMP -0.74 -11.92 -0.54 1.2100000000000001e-27 Colorectal cancer; LIHC cis rs4474465 0.850 rs4285892 chr11:78243134 C/A cg27205649 chr11:78285834 NARS2 0.41 6.52 0.33 2.49e-10 Alzheimer's disease (survival time); LIHC cis rs651907 0.535 rs35799195 chr3:101521927 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11582133 chr15:41576691 LOC729082 0.42 6.1 0.31 2.89e-9 Cognitive function; LIHC cis rs7098414 0.511 rs7899545 chr10:82150635 G/C cg00277334 chr10:82204260 NA -0.6 -9.8 -0.47 3.84e-20 Post bronchodilator FEV1; LIHC cis rs9560113 0.509 rs4771759 chr13:112209217 A/G cg10483660 chr13:112241077 NA -0.24 -6.11 -0.31 2.71e-9 Menarche (age at onset); LIHC cis rs240764 0.658 rs11155659 chr6:101222568 A/G cg09795085 chr6:101329169 ASCC3 -0.56 -8.09 -0.4 1.09e-14 Neuroticism; LIHC cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg22800045 chr5:56110881 MAP3K1 -0.68 -8.84 -0.43 5.33e-17 Initial pursuit acceleration; LIHC cis rs7208859 0.673 rs216440 chr17:28928309 A/T cg13385521 chr17:29058706 SUZ12P 0.58 5.78 0.3 1.65e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg08125733 chr17:73851984 WBP2 0.89 13.28 0.58 9.91e-33 Psoriasis; LIHC cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg21448741 chr8:58168803 NA 0.35 6.51 0.33 2.73e-10 Developmental language disorder (linguistic errors); LIHC cis rs295140 0.546 rs295137 chr2:201150040 C/T cg23649088 chr2:200775458 C2orf69 0.43 5.89 0.3 9.14e-9 QT interval; LIHC cis rs2274273 0.875 rs2075602 chr14:55609774 A/G cg01864836 chr14:55583639 NA -0.42 -8.23 -0.41 4.02e-15 Protein biomarker; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg11905131 chr22:24372483 LOC391322 -0.78 -12.08 -0.55 3.19e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs701145 0.556 rs357502 chr3:153955950 C/T cg16511985 chr3:153974050 SGEF 0.43 9.22 0.45 3.03e-18 Coronary artery disease; LIHC cis rs6783573 0.683 rs3806702 chr3:46617502 T/C cg16875182 chr3:46619291 LRRC2;TDGF1 -0.54 -6.27 -0.32 1.1e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs11098499 0.863 rs9884402 chr4:120489982 A/G cg09307838 chr4:120376055 NA 0.75 11.73 0.54 5.96e-27 Corneal astigmatism; LIHC cis rs7772486 0.597 rs9386136 chr6:146158300 A/T cg05347473 chr6:146136440 FBXO30 0.48 7.21 0.36 3.71e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs7647973 0.961 rs62259943 chr3:49425167 A/G cg07636037 chr3:49044803 WDR6 -0.53 -6.28 -0.32 1.05e-9 Menarche (age at onset); LIHC trans rs2516739 1.000 rs2516740 chr16:2097110 A/C cg13974317 chr22:21056282 TMEM191A 0.52 6.21 0.32 1.54e-9 Longevity; LIHC trans rs208520 0.690 rs1738970 chr6:66809491 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.18 -0.44 4.33e-18 Exhaled nitric oxide output; LIHC cis rs11711311 1.000 rs7622403 chr3:113472434 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 -0.48 -9.31 -0.45 1.61e-18 IgG glycosylation; LIHC trans rs561341 0.883 rs886224 chr17:30229902 T/C cg20587970 chr11:113659929 NA -0.74 -8.45 -0.42 8.62e-16 Hip circumference adjusted for BMI; LIHC cis rs2304069 0.507 rs7728264 chr5:149394954 C/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.58 8.26 0.41 3.31e-15 HIV-1 control; LIHC cis rs1198430 0.683 rs534417 chr1:23784965 A/G cg13183780 chr1:23809682 ASAP3 -0.39 -6.77 -0.34 5.56e-11 Total cholesterol levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06045225 chr5:65892993 MAST4 0.43 6.41 0.33 4.76e-10 Cognitive function; LIHC cis rs933688 1.000 rs12651840 chr5:90729592 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.87 17.94 0.7 3.31e-51 Smoking behavior; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23895204 chr7:129845368 TMEM209 0.42 6.08 0.31 3.24e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088580 0.619 rs1205335 chr20:32927507 C/T cg08999081 chr20:33150536 PIGU -0.67 -13.19 -0.58 2.08e-32 Glomerular filtration rate (creatinine); LIHC cis rs9534288 0.797 rs9534277 chr13:46578349 T/C cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs12620999 0.941 rs4663240 chr2:238036632 G/T cg23555395 chr2:238036564 NA -0.32 -6.11 -0.31 2.71e-9 Systemic lupus erythematosus; LIHC cis rs7208859 0.614 rs216412 chr17:28903394 A/G cg13385521 chr17:29058706 SUZ12P -0.57 -5.92 -0.31 7.65e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9733 0.543 rs72702558 chr1:150683251 G/A cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC trans rs8002861 0.967 rs7999434 chr13:44482961 T/C cg17145862 chr1:211918768 LPGAT1 0.67 13.33 0.58 6.19e-33 Leprosy; LIHC cis rs9916302 0.851 rs4390625 chr17:37620347 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -13.69 -0.6 2.49e-34 Glomerular filtration rate (creatinine); LIHC cis rs1707322 0.721 rs28817701 chr1:46186050 C/T cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs937213 0.573 rs2412464 chr15:40303842 G/A cg16127683 chr15:40268777 EIF2AK4 -0.37 -6.16 -0.32 2.07e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs1568889 1.000 rs61236373 chr11:28212720 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.52 7.22 0.36 3.34e-12 Bipolar disorder; LIHC cis rs950173 1.000 rs13000153 chr2:172586067 A/G cg13550731 chr2:172543902 DYNC1I2 -0.79 -8.71 -0.43 1.31e-16 Hippocampal volume; LIHC cis rs11098499 0.865 rs9994730 chr4:120381564 A/C cg09307838 chr4:120376055 NA 0.77 12.14 0.55 1.93e-28 Corneal astigmatism; LIHC trans rs11039798 0.588 rs1814768 chr11:48987455 T/C cg15704280 chr7:45808275 SEPT13 0.58 6.53 0.33 2.33e-10 Axial length; LIHC cis rs1023500 1.000 rs1023497 chr22:42340508 C/G cg04733989 chr22:42467013 NAGA -0.48 -5.75 -0.3 1.96e-8 Schizophrenia; LIHC cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs1707322 0.964 rs796773 chr1:46564475 C/T cg06784218 chr1:46089804 CCDC17 -0.37 -6.73 -0.34 7.08e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 0.642 rs35526611 chr7:66094008 C/T cg18876405 chr7:65276391 NA -0.45 -7.93 -0.39 3.25e-14 Aortic root size; LIHC cis rs8083850 0.635 rs1367637 chr18:50860722 C/T cg24270629 chr18:50823537 DCC -0.55 -8.49 -0.42 6.22e-16 Intelligence (multi-trait analysis); LIHC cis rs7309 0.935 rs1921309 chr2:162048975 T/A cg08807892 chr2:162101083 NA 0.45 7.64 0.38 2.14e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; LIHC cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg16414030 chr3:133502952 NA 0.4 6.41 0.33 4.93e-10 Iron status biomarkers; LIHC cis rs1568889 0.877 rs7933326 chr11:28288416 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 7.06 0.36 9.26e-12 Bipolar disorder; LIHC cis rs6951245 0.810 rs117800627 chr7:1081075 G/C cg08132940 chr7:1081526 C7orf50 -0.77 -6.71 -0.34 7.99e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10876993 0.806 rs1689598 chr12:58050500 G/C cg18357645 chr12:58087776 OS9 0.53 8.58 0.42 3.26e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs7772486 0.875 rs7739371 chr6:146424353 C/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.1 -0.31 2.9e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2019216 0.605 rs907706 chr17:21982191 G/A cg14296220 chr9:32431791 ACO1 0.38 6.21 0.32 1.57e-9 Pelvic organ prolapse; LIHC cis rs3793683 0.928 rs10781585 chr10:134553369 C/A cg06453172 chr10:134556979 INPP5A 0.53 7.49 0.38 6.06e-13 Migraine; LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC trans rs2243480 1.000 rs7792391 chr7:65773429 A/G cg10756647 chr7:56101905 PSPH -1.03 -12.6 -0.56 3.61e-30 Diabetic kidney disease; LIHC cis rs7917772 0.532 rs10748829 chr10:104527244 G/A cg22532475 chr10:104410764 TRIM8 0.36 6.45 0.33 3.71e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7208859 0.623 rs55938328 chr17:29117010 T/C cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2153535 0.580 rs1932284 chr6:8477694 A/T cg07606381 chr6:8435919 SLC35B3 0.82 12.33 0.55 3.65e-29 Motion sickness; LIHC cis rs4684776 0.867 rs1562615 chr3:11373357 A/C cg00170343 chr3:11313890 ATG7 -0.5 -6.76 -0.34 5.95e-11 Small vessel stroke; LIHC cis rs9596863 1.000 rs7328595 chr13:54424070 G/A ch.13.53330881F chr13:54432880 NA -0.43 -6.0 -0.31 5.16e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs7917772 0.503 rs2031602 chr10:104307955 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.59 0.56 3.86e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1997103 1.000 rs2177805 chr7:55404381 T/A cg17469321 chr7:55412551 NA 0.48 7.09 0.36 7.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC trans rs6489882 0.867 rs7315441 chr12:113365687 G/T cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg11070056 chr1:107600091 PRMT6 -0.71 -12.25 -0.55 7.21e-29 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs35146811 0.586 rs10267212 chr7:99595422 T/C cg22906224 chr7:99728672 NA 0.49 6.52 0.33 2.46e-10 Coronary artery disease; LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.01 22.18 0.77 3.52e-68 Height; LIHC cis rs7107174 1.000 rs4945270 chr11:78068216 A/G cg02023728 chr11:77925099 USP35 0.47 8.8 0.43 7.08e-17 Testicular germ cell tumor; LIHC cis rs3806843 0.735 rs2563306 chr5:140070017 C/T cg16179182 chr5:140090404 VTRNA1-1 0.37 6.06 0.31 3.51e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1712517 1.000 rs3123794 chr10:105033742 A/G cg05636881 chr10:105038444 INA 0.4 6.48 0.33 3.18e-10 Migraine; LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg19318889 chr4:1322082 MAEA 0.62 10.03 0.48 6.56e-21 Longevity; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg06656553 chr16:89960601 TCF25 -0.48 -6.06 -0.31 3.56e-9 Skin colour saturation; LIHC cis rs2576037 0.526 rs9962523 chr18:44486414 A/T cg19077165 chr18:44547161 KATNAL2 -0.45 -6.8 -0.35 4.59e-11 Personality dimensions; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg11494091 chr17:61959527 GH2 0.36 6.1 0.31 2.85e-9 Height; LIHC cis rs7258465 0.931 rs34053595 chr19:18556749 T/C cg10790698 chr19:18539756 SSBP4 -0.37 -7.59 -0.38 2.99e-13 Breast cancer; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg17450446 chr1:160002111 PIGM -0.5 -6.37 -0.33 5.98e-10 Lung cancer in ever smokers; LIHC cis rs4820539 1.000 rs2267002 chr22:23456702 T/C cg21100191 chr22:23484243 RTDR1 0.83 14.77 0.62 1.57e-38 Bone mineral density; LIHC cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.14e-11 Alzheimer's disease; LIHC cis rs11229555 0.598 rs4519112 chr11:58176386 C/T cg15696309 chr11:58395628 NA -0.63 -7.49 -0.38 5.83e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs526821 1.000 rs526821 chr11:55306151 A/G cg04317927 chr11:55418816 OR4S2 0.36 6.98 0.35 1.53e-11 Pediatric bone mineral density (spine); LIHC cis rs4638749 0.734 rs35184015 chr2:108870540 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -6.06 -0.31 3.57e-9 Blood pressure; LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg21448741 chr8:58168803 NA -0.39 -6.44 -0.33 4.01e-10 Developmental language disorder (linguistic errors); LIHC cis rs79839061 0.518 rs11734537 chr4:869174 A/G cg07828340 chr4:882639 GAK 0.83 7.02 0.36 1.18e-11 Intelligence (multi-trait analysis); LIHC cis rs4759375 1.000 rs2271976 chr12:123751726 A/C cg00376283 chr12:123451042 ABCB9 -0.5 -6.24 -0.32 1.27e-9 HDL cholesterol; LIHC cis rs11792861 0.926 rs1051474 chr9:111881856 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.58 0.42 3.44e-16 Menarche (age at onset); LIHC cis rs11608355 0.545 rs918107 chr12:109904198 C/T cg05360138 chr12:110035743 NA -0.95 -10.85 -0.51 9.04e-24 Neuroticism; LIHC cis rs2070433 0.539 rs721131 chr21:47957767 T/C cg12379764 chr21:47803548 PCNT 0.64 9.86 0.47 2.39e-20 Lymphocyte counts; LIHC cis rs385076 0.502 rs13013695 chr2:32391231 G/A cg02381751 chr2:32503542 YIPF4 -0.46 -6.34 -0.32 7.44e-10 Interleukin-18 levels; LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg00091569 chr3:40428383 ENTPD3 0.38 6.38 0.33 5.64e-10 Renal cell carcinoma; LIHC cis rs7223966 1.000 rs8068603 chr17:61755211 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.92e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs35306767 0.903 rs12762228 chr10:880854 G/A cg26597838 chr10:835615 NA 1.49 17.34 0.68 8.86e-49 Eosinophil percentage of granulocytes; LIHC cis rs600806 0.888 rs2228604 chr1:109884775 A/C cg23091122 chr1:110024289 SYPL2 -0.48 -6.46 -0.33 3.67e-10 Intelligence (multi-trait analysis); LIHC cis rs12220238 1.000 rs10824090 chr10:75923446 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.71 0.34 7.86e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg18225595 chr11:63971243 STIP1 0.63 7.73 0.39 1.2e-13 Mean platelet volume; LIHC cis rs6918586 0.658 rs1572982 chr6:26094367 G/A cg18357526 chr6:26021779 HIST1H4A 0.56 8.32 0.41 2.2e-15 Schizophrenia; LIHC cis rs17106184 1.000 rs113119450 chr1:51235816 T/C cg07174182 chr1:51127561 FAF1 -0.61 -6.65 -0.34 1.18e-10 Type 2 diabetes; LIHC cis rs3917254 0.543 rs6752379 chr2:102746705 G/A cg22835712 chr2:102737379 NA -0.47 -5.75 -0.3 1.97e-8 Blood protein levels; LIHC cis rs8062405 0.690 rs7187604 chr16:28565953 A/G cg07382826 chr16:28625726 SULT1A1 0.49 7.6 0.38 2.78e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1728785 1.000 rs1749793 chr16:68569312 C/T cg02972257 chr16:68554789 NA -0.55 -6.28 -0.32 1.04e-9 Ulcerative colitis; LIHC cis rs7131987 0.903 rs67517901 chr12:29421346 A/G cg21522988 chr12:29376872 FAR2 0.28 6.41 0.33 4.84e-10 QT interval; LIHC cis rs7191700 0.674 rs12597893 chr16:11426331 A/G cg00044050 chr16:11439710 C16orf75 0.49 7.26 0.37 2.62e-12 Multiple sclerosis; LIHC cis rs10193935 0.901 rs62142639 chr2:42600019 C/G cg27598129 chr2:42591480 NA -0.7 -11.0 -0.51 2.64e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs7520050 0.966 rs6680380 chr1:46300189 T/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.08 0.31 3.26e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2731664 0.792 rs465670 chr5:176877624 C/T cg23176889 chr5:176863531 GRK6 -0.72 -12.76 -0.57 9.29e-31 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.966 rs12782948 chr10:35450607 G/A cg04310649 chr10:35416472 CREM -0.43 -5.82 -0.3 1.39e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13236679 chr6:37467396 C6orf129 0.43 7.24 0.36 2.94e-12 Pancreatic cancer; LIHC cis rs9399135 0.636 rs7749106 chr6:135268142 G/A cg22676075 chr6:135203613 NA 0.38 6.01 0.31 4.71e-9 Red blood cell count; LIHC cis rs7945705 0.934 rs1988709 chr11:8882890 A/T cg21881798 chr11:8931708 C11orf17;ST5 0.43 7.26 0.37 2.58e-12 Hemoglobin concentration; LIHC cis rs55665837 0.540 rs3206554 chr11:14797945 A/T cg25251204 chr11:14927456 NA 0.4 5.75 0.3 1.98e-8 Vitamin D levels; LIHC cis rs12620999 0.941 rs10929215 chr2:238037456 G/A cg23555395 chr2:238036564 NA -0.32 -6.11 -0.31 2.71e-9 Systemic lupus erythematosus; LIHC cis rs12478296 1.000 rs57603292 chr2:243028537 G/A cg18898632 chr2:242989856 NA -0.69 -8.68 -0.42 1.67e-16 Obesity-related traits; LIHC cis rs858239 0.601 rs3735228 chr7:23170427 T/G cg23682824 chr7:23144976 KLHL7 0.45 6.7 0.34 8.73e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs7756236 0.521 rs6936993 chr6:36626322 C/T cg08179530 chr6:36648295 CDKN1A -0.4 -5.93 -0.31 7.23e-9 QRS duration; LIHC cis rs61677309 0.964 rs12576118 chr11:118158440 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs6964587 1.000 rs2075881 chr7:91734552 T/C cg17063962 chr7:91808500 NA 1.04 20.83 0.75 8.28e-63 Breast cancer; LIHC cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg02359409 chr6:42947317 PEX6 0.46 6.1 0.31 2.83e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs829883 0.763 rs249843 chr12:98870987 G/A cg25150519 chr12:98850993 NA 0.65 9.98 0.48 9.07e-21 Colorectal adenoma (advanced); LIHC cis rs9640161 0.830 rs17173682 chr7:150059602 A/G cg10018233 chr7:150070692 REPIN1 0.66 12.26 0.55 6.94e-29 Blood protein levels;Circulating chemerin levels; LIHC trans rs10411161 0.810 rs72626248 chr19:52357246 T/C cg22319618 chr22:45562946 NUP50 -0.51 -6.35 -0.32 6.98e-10 Breast cancer; LIHC cis rs17125944 0.615 rs2025632 chr14:53294319 T/C cg00686598 chr14:53173677 PSMC6 -0.86 -10.04 -0.48 6e-21 Alzheimer's disease (late onset); LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg05590025 chr7:65112418 INTS4L2 -0.65 -7.33 -0.37 1.68e-12 Diabetic kidney disease; LIHC cis rs3106136 0.678 rs7658830 chr4:95295134 A/G cg11021082 chr4:95130006 SMARCAD1 0.34 5.77 0.3 1.74e-8 Capecitabine sensitivity; LIHC cis rs7103648 0.932 rs7104036 chr11:47462140 A/G cg20307385 chr11:47447363 PSMC3 1.04 18.81 0.71 1.09e-54 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs875971 0.862 rs2420611 chr7:65999320 A/G cg11764359 chr7:65958608 NA 0.78 13.61 0.59 5.2e-34 Aortic root size; LIHC cis rs7246657 0.943 rs10417503 chr19:37842735 T/C cg23950597 chr19:37808831 NA -0.53 -6.98 -0.35 1.55e-11 Coronary artery calcification; LIHC cis rs7412746 0.553 rs59337856 chr1:150746406 G/T cg17724175 chr1:150552817 MCL1 0.46 9.16 0.44 4.94e-18 Melanoma; LIHC cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg13395646 chr4:1353034 KIAA1530 -0.66 -9.54 -0.46 2.84e-19 Obesity-related traits; LIHC cis rs7224737 1.000 rs35184688 chr17:40272406 G/C cg02450064 chr17:40260053 DHX58 -0.29 -5.86 -0.3 1.1e-8 Fibrinogen levels; LIHC cis rs12995491 0.763 rs1914735 chr2:88511953 A/T cg04511125 chr2:88470314 THNSL2 -0.45 -6.56 -0.33 2.01e-10 Response to metformin (IC50); LIHC cis rs831571 1.000 rs166230 chr3:64053207 T/C cg16258503 chr3:63850278 ATXN7;THOC7 0.52 6.36 0.33 6.62e-10 Type 2 diabetes; LIHC cis rs35079168 0.661 rs3118529 chr9:137304915 C/T cg00753924 chr9:137298813 RXRA -0.34 -5.87 -0.3 1.05e-8 Intelligence; LIHC cis rs918629 0.530 rs3777185 chr5:95259862 C/T cg10483112 chr5:95245456 ELL2 -0.38 -6.96 -0.35 1.75e-11 IgG glycosylation; LIHC cis rs796364 0.806 rs112486506 chr2:201073947 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.37 -0.41 1.53e-15 Schizophrenia; LIHC cis rs9918079 0.560 rs4698402 chr4:15629803 G/A cg21123203 chr4:15471301 CC2D2A -0.44 -6.98 -0.35 1.55e-11 Obesity-related traits; LIHC cis rs7726839 0.578 rs10080150 chr5:593160 C/T cg23206463 chr5:561769 NA 0.5 7.77 0.39 9.29e-14 Obesity-related traits; LIHC cis rs459571 0.959 rs2520099 chr9:136918139 T/C cg13789015 chr9:136890014 NCRNA00094 0.44 8.0 0.4 1.99e-14 Platelet distribution width; LIHC cis rs2549003 1.000 rs2070722 chr5:131824486 A/C cg21138405 chr5:131827807 IRF1 0.37 9.74 0.47 6.25e-20 Asthma (sex interaction); LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.97 23.47 0.79 2.97e-73 Prudent dietary pattern; LIHC cis rs1707322 0.927 rs6690386 chr1:46253011 C/T cg06784218 chr1:46089804 CCDC17 0.39 6.87 0.35 2.99e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1075232 0.826 rs12438813 chr15:31705913 C/T cg17859187 chr1:168147929 TIPRL 0.75 6.04 0.31 3.96e-9 Survival in colorectal cancer (non-distant metastatic); LIHC cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -9.98 -0.47 9.38e-21 Platelet count; LIHC cis rs96067 0.772 rs6700737 chr1:36598214 A/G cg24686825 chr1:36642396 MAP7D1 -0.56 -7.9 -0.39 3.84e-14 Corneal structure; LIHC cis rs986417 0.786 rs2038277 chr14:61083662 G/A cg27398547 chr14:60952738 C14orf39 0.67 6.53 0.33 2.33e-10 Gut microbiota (bacterial taxa); LIHC cis rs1568889 0.838 rs4614434 chr11:28302234 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 14.55 0.62 1.15e-37 Bipolar disorder; LIHC cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg17971929 chr21:40555470 PSMG1 0.85 10.33 0.49 5.75e-22 Cognitive function; LIHC trans rs7714584 1.000 rs7709464 chr5:150269441 C/A cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs523522 0.962 rs4767902 chr12:120910004 C/T cg27279351 chr12:120934652 DYNLL1 0.67 11.84 0.54 2.46e-27 High light scatter reticulocyte count; LIHC cis rs9486715 0.867 rs2475025 chr6:96988696 A/T cg06623918 chr6:96969491 KIAA0776 -0.86 -15.49 -0.64 2.31e-41 Headache; LIHC trans rs72960926 0.744 rs11752717 chr6:74954435 G/A cg07247405 chr1:2484626 LOC115110 0.53 6.38 0.33 5.78e-10 Metabolite levels (MHPG); LIHC cis rs12915845 0.603 rs11073783 chr15:89043761 C/T cg05013243 chr15:89149849 MIR1179 -0.37 -6.6 -0.34 1.55e-10 Menarche (age at onset); LIHC cis rs10504073 0.565 rs974780 chr8:49930976 G/A cg00325661 chr8:49890786 NA 0.39 9.53 0.46 2.97e-19 Blood metabolite ratios; LIHC trans rs2742417 0.603 rs2742448 chr3:45764246 C/T cg09622330 chr16:10205262 GRIN2A 0.31 6.31 0.32 8.79e-10 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs875971 0.638 rs10278816 chr7:66036987 T/C cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg05564831 chr3:52568323 NT5DC2 -0.39 -6.24 -0.32 1.32e-9 Bipolar disorder; LIHC cis rs7927771 0.560 rs4752858 chr11:47685829 C/T cg20307385 chr11:47447363 PSMC3 -0.71 -10.74 -0.5 2.27e-23 Subjective well-being; LIHC cis rs965469 0.841 rs113139885 chr20:3219561 G/A cg25506879 chr20:3388711 C20orf194 -0.54 -5.95 -0.31 6.65e-9 IFN-related cytopenia; LIHC cis rs11971779 0.588 rs2003531 chr7:139126578 A/G cg07862535 chr7:139043722 LUC7L2 0.6 9.97 0.47 1.01e-20 Diisocyanate-induced asthma; LIHC trans rs2681424 0.966 rs62269210 chr3:121760603 C/T cg03946530 chr15:65596423 NA -0.48 -6.2 -0.32 1.67e-9 Multiple sclerosis; LIHC cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg16325326 chr1:53192061 ZYG11B -0.53 -9.14 -0.44 5.62e-18 Monocyte count; LIHC cis rs11585357 0.895 rs34324150 chr1:17632464 C/G cg08277548 chr1:17600880 PADI3 -0.62 -6.56 -0.33 1.96e-10 Hair shape; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg10480950 chr6:5067127 NA -0.35 -6.32 -0.32 7.93e-10 Pain; LIHC cis rs7772486 0.641 rs2777485 chr6:146334377 G/A cg23711669 chr6:146136114 FBXO30 0.58 8.84 0.43 5.32e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs12824058 0.831 rs4759655 chr12:130815740 A/G cg24229701 chr12:130821962 PIWIL1 -0.41 -6.28 -0.32 1.03e-9 Menopause (age at onset); LIHC cis rs595982 0.527 rs35023389 chr19:49377873 G/A cg21252483 chr19:49399788 TULP2 -0.94 -10.31 -0.49 6.77e-22 Red cell distribution width; LIHC cis rs67311347 1.000 rs6599102 chr3:40468406 G/A cg13409248 chr3:40428643 ENTPD3 0.4 6.78 0.34 5.44e-11 Renal cell carcinoma; LIHC cis rs35110281 0.748 rs1584918 chr21:45042419 C/T cg04455712 chr21:45112962 RRP1B 0.47 7.85 0.39 5.34e-14 Mean corpuscular volume; LIHC cis rs6500602 0.702 rs2058812 chr16:4524443 C/G cg08645402 chr16:4508243 NA 0.45 8.68 0.42 1.69e-16 Schizophrenia; LIHC cis rs7666738 0.546 rs10026181 chr4:98814118 C/T cg05340658 chr4:99064831 C4orf37 -0.5 -6.63 -0.34 1.29e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg06873352 chr17:61820015 STRADA 0.6 9.31 0.45 1.59e-18 Height; LIHC cis rs9918079 0.560 rs7662032 chr4:15635414 C/G cg24225360 chr4:15471699 CC2D2A -0.38 -6.17 -0.32 1.92e-9 Obesity-related traits; LIHC cis rs798554 0.642 rs2533871 chr7:2883006 C/G cg04166393 chr7:2884313 GNA12 0.53 8.3 0.41 2.38e-15 Height; LIHC cis rs6430585 0.646 rs1057031 chr2:136633962 G/A cg15123519 chr2:136567270 LCT -0.38 -6.19 -0.32 1.68e-9 Corneal structure; LIHC cis rs10791097 0.667 rs4937585 chr11:130741940 A/G cg22079354 chr11:130786696 SNX19 0.41 5.93 0.31 7.46e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg24549020 chr5:56110836 MAP3K1 0.48 6.28 0.32 1.03e-9 Initial pursuit acceleration; LIHC cis rs4595586 0.525 rs17464772 chr12:39247777 G/A cg26384229 chr12:38710491 ALG10B 0.51 6.77 0.34 5.79e-11 Morning vs. evening chronotype; LIHC cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg18305652 chr10:134549665 INPP5A 0.44 6.4 0.33 5.22e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6089584 0.924 rs6142906 chr20:60552554 G/C cg13770153 chr20:60521292 NA -0.34 -6.71 -0.34 7.89e-11 Body mass index; LIHC cis rs7772486 0.790 rs4280983 chr6:146280790 G/C cg23711669 chr6:146136114 FBXO30 -0.71 -12.18 -0.55 1.33e-28 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26609550 chr19:14017309 C19orf57;CC2D1A 0.43 6.21 0.32 1.57e-9 Lung function (FEV1/FVC); LIHC trans rs2727020 0.521 rs10839296 chr11:49537617 T/C cg18944383 chr4:111397179 ENPEP -0.34 -7.99 -0.4 2.14e-14 Coronary artery disease; LIHC cis rs10791323 0.538 rs1105494 chr11:133698733 A/C cg06766960 chr11:133703094 NA 0.55 8.68 0.42 1.66e-16 Childhood ear infection; LIHC cis rs7149337 0.780 rs4369569 chr14:51689181 C/G cg23942311 chr14:51606299 NA -0.37 -7.81 -0.39 6.98e-14 Cancer; LIHC trans rs8073060 0.586 rs7221203 chr17:34015532 T/C cg19694781 chr19:47549865 TMEM160 -1.25 -13.18 -0.58 2.36e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs9611565 0.649 rs5758442 chr22:42133060 T/C cg06634786 chr22:41940651 POLR3H 0.57 6.25 0.32 1.23e-9 Vitiligo; LIHC cis rs6545883 0.929 rs2593625 chr2:61668769 C/T cg14146966 chr2:61757674 XPO1 0.45 7.69 0.38 1.61e-13 Tuberculosis; LIHC cis rs6456156 0.586 rs7762156 chr6:167485831 A/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.51 -0.42 5.66e-16 Primary biliary cholangitis; LIHC cis rs12478296 0.901 rs59477854 chr2:243015490 T/C cg18898632 chr2:242989856 NA -0.46 -6.35 -0.32 6.98e-10 Obesity-related traits; LIHC cis rs611744 0.967 rs653081 chr8:109230383 G/T cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs2842992 0.830 rs2273819 chr6:160183325 G/C cg19482086 chr6:160211437 TCP1;MRPL18 0.68 11.91 0.54 1.3e-27 Age-related macular degeneration (geographic atrophy); LIHC cis rs7618501 1.000 rs7374277 chr3:49784777 T/C cg21467203 chr3:49911342 NA 0.39 6.63 0.34 1.28e-10 Intelligence (multi-trait analysis); LIHC cis rs738322 0.718 rs2899297 chr22:38594668 A/G cg25457927 chr22:38595422 NA -0.44 -11.4 -0.52 1e-25 Cutaneous nevi; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22430790 chr14:52117833 FRMD6 0.46 7.08 0.36 8.12e-12 Pancreatic cancer; LIHC cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg07414643 chr4:187882934 NA 0.24 6.15 0.32 2.11e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6089584 0.566 rs6061964 chr20:60607536 G/A cg06108461 chr20:60628389 TAF4 -0.65 -9.2 -0.45 3.65e-18 Body mass index; LIHC cis rs16828019 0.852 rs12759023 chr1:41603978 T/C cg03962019 chr1:41807865 NA 0.53 7.51 0.38 5.27e-13 Intelligence (multi-trait analysis); LIHC cis rs9911578 1.000 rs4793952 chr17:56608465 C/T cg05425664 chr17:57184151 TRIM37 0.59 8.71 0.43 1.35e-16 Intelligence (multi-trait analysis); LIHC cis rs6430585 0.941 rs12469551 chr2:136510012 T/G cg15123519 chr2:136567270 LCT 0.35 5.83 0.3 1.28e-8 Corneal structure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg12112058 chr1:224622605 WDR26 0.39 6.15 0.32 2.13e-9 Cognitive function; LIHC cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg08888203 chr3:10149979 C3orf24 -0.56 -6.45 -0.33 3.75e-10 Alzheimer's disease; LIHC cis rs7937890 0.599 rs2597204 chr11:14481017 C/T cg23387056 chr11:14280742 SPON1 -0.47 -6.19 -0.32 1.69e-9 Mitochondrial DNA levels; LIHC cis rs2228479 0.850 rs11076624 chr16:89855749 T/C cg06558623 chr16:89946397 TCF25 0.85 11.06 0.51 1.62e-24 Skin colour saturation; LIHC cis rs4924590 0.550 rs1426889 chr15:42231658 C/T cg20935245 chr15:42234343 EHD4 -0.42 -7.86 -0.39 4.98e-14 Lymphocyte percentage of white cells;Sum basophil neutrophil counts;Granulocyte count; LIHC cis rs8060686 0.516 rs7189794 chr16:68277727 T/C cg05110241 chr16:68378359 PRMT7 -0.55 -6.46 -0.33 3.63e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs7582720 1.000 rs72926769 chr2:203798318 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs5753618 0.561 rs4141404 chr22:31675185 A/C cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs2075371 1.000 rs2598286 chr7:133976029 G/A cg11752832 chr7:134001865 SLC35B4 0.48 7.36 0.37 1.34e-12 Mean platelet volume; LIHC cis rs1707322 0.721 rs6665808 chr1:46162283 C/T cg03146154 chr1:46216737 IPP 0.59 10.17 0.48 2.07e-21 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs986417 1.000 rs1951115 chr14:60922006 G/C cg27398547 chr14:60952738 C14orf39 -0.81 -9.56 -0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg21872391 chr10:112064057 SMNDC1 0.43 6.08 0.31 3.23e-9 Morning vs. evening chronotype; LIHC cis rs892961 0.899 rs72896162 chr17:75412521 A/G cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs11583043 0.874 rs72734253 chr1:101380718 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.58 7.92 0.39 3.46e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg13607699 chr17:42295918 UBTF 0.44 7.14 0.36 5.61e-12 Total body bone mineral density; LIHC cis rs7208859 0.614 rs9914534 chr17:29202664 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.13 0.31 2.4e-9 Menopause (age at onset); LIHC cis rs10870270 1.000 rs7077744 chr10:133770201 C/T cg17892150 chr10:133769511 PPP2R2D -0.68 -12.84 -0.57 4.5e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs8141529 0.778 rs763073 chr22:29215542 G/A cg02153584 chr22:29168773 CCDC117 0.58 9.25 0.45 2.56e-18 Lymphocyte counts; LIHC cis rs4979906 1.000 rs11002248 chr10:79446961 A/G cg07817648 chr10:79422355 NA -0.29 -6.34 -0.32 7.44e-10 Mortality in heart failure; LIHC cis rs1385374 0.502 rs923077 chr12:129276708 C/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.57 -6.89 -0.35 2.63e-11 Systemic lupus erythematosus; LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs77633900 0.614 rs2439993 chr15:76861532 G/A cg21673338 chr15:77095150 SCAPER -0.5 -7.32 -0.37 1.83e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs709400 0.827 rs2274269 chr14:104029246 G/A cg26031613 chr14:104095156 KLC1 1.12 14.18 0.61 3.29e-36 Body mass index; LIHC cis rs7909074 0.714 rs10900129 chr10:45398609 G/C cg04218760 chr10:45406644 TMEM72 -0.2 -5.86 -0.3 1.11e-8 Mean corpuscular volume; LIHC cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.74e-9 Bipolar disorder; LIHC cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg02244288 chr16:89573955 SPG7 -0.31 -5.91 -0.3 8.07e-9 Multiple myeloma (IgH translocation); LIHC cis rs1816752 0.805 rs61614647 chr13:25015967 C/T cg22771759 chr13:24902376 NA 0.32 6.76 0.34 5.94e-11 Obesity-related traits; LIHC cis rs8072100 0.817 rs9905581 chr17:45547185 C/T cg08085267 chr17:45401833 C17orf57 -0.44 -6.47 -0.33 3.47e-10 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7756236 0.521 rs6930671 chr6:36625272 T/C cg08179530 chr6:36648295 CDKN1A 0.42 6.35 0.32 7e-10 QRS duration; LIHC cis rs6582630 0.560 rs12315134 chr12:38419857 T/A cg26384229 chr12:38710491 ALG10B -0.46 -6.02 -0.31 4.55e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs7520050 0.966 rs6672898 chr1:46290588 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.75 0.3 2.03e-8 Red blood cell count;Reticulocyte count; LIHC cis rs67311347 1.000 rs11716675 chr3:40485280 G/T cg00656387 chr3:40428638 ENTPD3 0.42 7.02 0.35 1.21e-11 Renal cell carcinoma; LIHC cis rs2204008 0.683 rs11519834 chr12:38053575 T/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs2274273 0.870 rs67514154 chr14:55767382 T/C cg01864836 chr14:55583639 NA -0.37 -6.55 -0.33 2.15e-10 Protein biomarker; LIHC cis rs2072499 0.750 rs10159384 chr1:156160822 C/T cg25208724 chr1:156163844 SLC25A44 0.72 8.19 0.4 5.38e-15 Testicular germ cell tumor; LIHC cis rs6964587 1.000 rs11772102 chr7:91558326 A/T cg17063962 chr7:91808500 NA -1.01 -19.28 -0.72 1.37e-56 Breast cancer; LIHC cis rs780096 0.526 rs10182937 chr2:27651693 T/C cg27432699 chr2:27873401 GPN1 -0.52 -7.54 -0.38 4.34e-13 Total body bone mineral density; LIHC cis rs13161895 1.000 rs13161895 chr5:179471201 C/T cg06664874 chr5:179499304 RNF130 0.61 7.56 0.38 3.66e-13 LDL cholesterol; LIHC cis rs9467773 1.000 rs9467791 chr6:26562486 A/G cg09904177 chr6:26538194 HMGN4 -0.64 -13.56 -0.59 8.21e-34 Intelligence (multi-trait analysis); LIHC cis rs2997447 0.761 rs17356867 chr1:26448849 C/T cg19633962 chr1:26362018 EXTL1 0.66 6.28 0.32 1.01e-9 QRS complex (12-leadsum); LIHC cis rs9929218 0.679 rs9924886 chr16:68743939 A/C cg01231543 chr16:68741748 NA 0.37 5.73 0.3 2.23e-8 Colorectal cancer; LIHC cis rs7044106 0.762 rs3903886 chr9:123383646 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.67 -10.63 -0.5 5.56e-23 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs1000083 0.666 rs291805 chr5:96741146 A/G ch.5.96698337R chr5:96672581 NA 0.86 6.86 0.35 3.31e-11 Cisplatin-induced ototoxicity; LIHC cis rs1707322 0.721 rs6429574 chr1:46134054 A/G cg06784218 chr1:46089804 CCDC17 0.4 7.46 0.37 7.02e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg25894440 chr7:65020034 NA 0.55 6.21 0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs4803468 1.000 rs4674 chr19:41930396 A/G cg14132834 chr19:41945861 ATP5SL -0.46 -6.67 -0.34 1e-10 Height; LIHC trans rs4843747 0.671 rs72818577 chr16:88111181 G/A cg09572067 chr16:29127029 RRN3P2 0.52 8.38 0.41 1.42e-15 Menopause (age at onset); LIHC cis rs3818285 0.655 rs623980 chr10:111646147 C/T cg00817464 chr10:111662876 XPNPEP1 -0.63 -10.53 -0.49 1.22e-22 Superior crus of antihelix expression; LIHC cis rs7577696 0.597 rs34197800 chr2:32389646 C/A cg02381751 chr2:32503542 YIPF4 -0.45 -6.22 -0.32 1.42e-9 Inflammatory biomarkers; LIHC cis rs12477438 0.520 rs8179690 chr2:99795300 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.2 -21.42 -0.76 3.83e-65 Chronic sinus infection; LIHC cis rs7572733 0.534 rs700687 chr2:198721560 A/T cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs782590 0.967 rs4672054 chr2:55773093 C/A cg18811423 chr2:55921094 PNPT1 0.98 15.35 0.64 7.97e-41 Metabolic syndrome; LIHC cis rs1801251 1.000 rs283477 chr2:233649427 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.12 0.52 9.61e-25 Coronary artery disease; LIHC cis rs2933343 0.621 rs883843 chr3:128567383 C/T cg24203234 chr3:128598194 ACAD9 -0.43 -5.91 -0.3 8.31e-9 IgG glycosylation; LIHC cis rs1577917 0.566 rs2842611 chr6:86302034 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.11 -0.31 2.75e-9 Response to antipsychotic treatment; LIHC cis rs1559088 0.948 rs7247748 chr19:33594023 T/C cg17764715 chr19:33622953 WDR88 0.45 6.58 0.34 1.77e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs10464366 0.746 rs34792397 chr7:39146331 G/A cg20302533 chr7:39170763 POU6F2 0.35 6.44 0.33 4.04e-10 IgG glycosylation; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18018498 chr11:102962968 DCUN1D5 -0.43 -6.33 -0.32 7.74e-10 Pancreatic cancer; LIHC cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg24675658 chr1:53192096 ZYG11B 0.64 10.05 0.48 5.28e-21 Monocyte count; LIHC cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg07677032 chr17:61819896 STRADA 0.43 6.07 0.31 3.49e-9 Prudent dietary pattern; LIHC cis rs2455799 0.593 rs2062823 chr3:15732256 G/T cg12698662 chr3:15914712 MIR563 -0.38 -6.94 -0.35 1.95e-11 Mean platelet volume; LIHC cis rs4820539 1.000 rs2157710 chr22:23457486 C/T cg14186256 chr22:23484241 RTDR1 0.92 19.43 0.72 3.56e-57 Bone mineral density; LIHC cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg00684032 chr4:1343700 KIAA1530 0.39 6.56 0.33 2.03e-10 Obesity-related traits; LIHC cis rs6545883 0.895 rs796597 chr2:61681060 A/G cg14146966 chr2:61757674 XPO1 0.47 8.17 0.4 6.09e-15 Tuberculosis; LIHC cis rs897984 0.553 rs2335013 chr16:30877346 T/G cg02466173 chr16:30829666 NA 0.48 7.4 0.37 1.05e-12 Dementia with Lewy bodies; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg12516959 chr21:47718080 NA 0.36 5.85 0.3 1.17e-8 Testicular germ cell tumor; LIHC cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg16145915 chr7:1198662 ZFAND2A -0.41 -10.4 -0.49 3.53e-22 Longevity;Endometriosis; LIHC cis rs12291225 0.839 rs4757244 chr11:14258655 A/G cg19336497 chr11:14380999 RRAS2 0.49 9.0 0.44 1.58e-17 Sense of smell; LIHC cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg11502198 chr6:26597334 ABT1 0.62 9.73 0.47 6.48e-20 Intelligence (multi-trait analysis); LIHC trans rs875971 0.737 rs7803424 chr7:65880605 T/C cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs6952808 0.823 rs10950448 chr7:1966492 G/C cg14004847 chr7:1930337 MAD1L1 -0.44 -6.26 -0.32 1.15e-9 Bipolar disorder and schizophrenia; LIHC cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg04772025 chr11:68637568 NA 0.45 5.72 0.3 2.37e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs34172651 0.583 rs4787649 chr16:24700215 C/T cg04756594 chr16:24857601 SLC5A11 -0.38 -6.27 -0.32 1.07e-9 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.62 0.38 2.51e-13 Prudent dietary pattern; LIHC cis rs7264396 0.943 rs224421 chr20:34145461 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.36 -5.81 -0.3 1.47e-8 Total cholesterol levels; LIHC cis rs9457247 1.000 rs2769352 chr6:167378619 A/G cg23791538 chr6:167370224 RNASET2 0.6 9.48 0.46 4.34e-19 Crohn's disease; LIHC cis rs9640161 0.789 rs2159234 chr7:150020422 A/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.37 -0.41 1.52e-15 Blood protein levels;Circulating chemerin levels; LIHC trans rs8113308 0.810 rs7255377 chr19:52451338 T/C cg14959425 chr7:20447707 ITGB8 -0.47 -6.11 -0.31 2.75e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs7107174 0.892 rs12281104 chr11:78046940 T/C cg02023728 chr11:77925099 USP35 0.43 8.44 0.42 9.09e-16 Testicular germ cell tumor; LIHC cis rs12365397 1.000 rs12365397 chr11:43236061 A/G cg16667275 chr11:43333495 API5 0.45 6.18 0.32 1.87e-9 Migraine; LIHC cis rs8062405 0.755 rs1074631 chr16:28554108 A/G cg07382826 chr16:28625726 SULT1A1 -0.49 -7.51 -0.38 5.26e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9399135 0.967 rs7750300 chr6:135350950 C/G cg24558204 chr6:135376177 HBS1L 0.44 7.15 0.36 5.13e-12 Red blood cell count; LIHC cis rs1499614 1.000 rs2707830 chr7:66167645 T/C cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs7726839 0.540 rs57306627 chr5:597643 T/C cg09021430 chr5:549028 NA -0.42 -8.44 -0.42 9.17e-16 Obesity-related traits; LIHC cis rs763121 0.853 rs6001188 chr22:39062194 T/C cg14440974 chr22:39074834 NA -0.43 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC cis rs4561483 0.603 rs17235629 chr16:11932421 C/T cg08843971 chr16:11963173 GSPT1 -0.34 -6.53 -0.33 2.34e-10 Testicular germ cell tumor; LIHC cis rs3736594 0.513 rs3811644 chr2:27802805 A/G cg27432699 chr2:27873401 GPN1 0.46 6.85 0.35 3.45e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs1534166 0.507 rs3811657 chr3:133474607 C/T cg27366882 chr3:133540807 NA -0.43 -5.76 -0.3 1.85e-8 Alcohol consumption (transferrin glycosylation); LIHC cis rs600806 0.888 rs3879449 chr1:109904971 A/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs72634258 0.554 rs34020118 chr1:7895015 C/T cg00864860 chr1:7907996 UTS2 0.64 5.84 0.3 1.21e-8 Inflammatory bowel disease; LIHC cis rs4969178 0.622 rs4129767 chr17:76403984 G/A cg02836325 chr17:76403955 PGS1 0.34 6.69 0.34 8.91e-11 HDL cholesterol levels; LIHC cis rs8067354 0.645 rs2645467 chr17:57854783 C/T cg13753209 chr17:57696993 CLTC 0.72 11.38 0.52 1.15e-25 Hemoglobin concentration; LIHC cis rs7586673 0.866 rs7579662 chr2:161915810 G/A cg21518248 chr2:162101506 NA 0.39 5.73 0.3 2.22e-8 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.747 rs2568045 chr11:9004060 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.48 -8.53 -0.42 4.85e-16 Hemoglobin concentration; LIHC cis rs1707322 1.000 rs12097799 chr1:46459886 C/A cg03146154 chr1:46216737 IPP 0.48 7.77 0.39 9.54e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.506 rs2991983 chr1:46079391 T/C cg24296786 chr1:45957014 TESK2 0.42 6.03 0.31 4.34e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10493773 0.532 rs1889919 chr1:86180034 A/G cg17807903 chr1:86174739 ZNHIT6 -0.59 -11.65 -0.53 1.25e-26 Urate levels in overweight individuals; LIHC cis rs12620999 1.000 rs12620999 chr2:238036367 C/T cg23555395 chr2:238036564 NA -0.32 -6.11 -0.31 2.71e-9 Systemic lupus erythematosus; LIHC cis rs1008375 0.966 rs2191504 chr4:17675592 C/G cg02297831 chr4:17616191 MED28 0.42 6.69 0.34 9.02e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs8002861 0.935 rs9533678 chr13:44463409 C/T cg17145862 chr1:211918768 LPGAT1 0.67 13.29 0.58 8.45e-33 Leprosy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13045639 chr21:40555880 PSMG1 -0.47 -6.43 -0.33 4.35e-10 Pancreatic cancer; LIHC cis rs919433 0.679 rs6757632 chr2:198530266 C/T cg10820045 chr2:198174542 NA 0.45 7.19 0.36 4.2e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs769267 0.965 rs4808200 chr19:19554803 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.49 7.44 0.37 8.16e-13 Tonsillectomy; LIHC cis rs11785400 1.000 rs754957 chr8:143746416 A/G cg24634471 chr8:143751801 JRK 0.51 8.14 0.4 7.61e-15 Schizophrenia; LIHC cis rs2404602 0.608 rs12439484 chr15:76602937 A/C cg03037974 chr15:76606532 NA 0.91 23.59 0.79 1.02e-73 Blood metabolite levels; LIHC cis rs2839186 0.872 rs13052233 chr21:47707284 G/T cg09417038 chr21:47716443 C21orf57 -0.5 -7.34 -0.37 1.55e-12 Testicular germ cell tumor; LIHC cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg06634786 chr22:41940651 POLR3H 0.82 9.21 0.45 3.39e-18 Vitiligo; LIHC cis rs903552 0.800 rs8026048 chr15:102006353 G/A cg00659931 chr15:102010125 PCSK6 -0.49 -6.75 -0.34 6.41e-11 Diabetic kidney disease; LIHC cis rs7927592 0.913 rs11228292 chr11:68379772 C/T cg16797656 chr11:68205561 LRP5 0.5 7.73 0.39 1.21e-13 Total body bone mineral density; LIHC cis rs7224685 0.569 rs28481302 chr17:4011527 T/G cg11204139 chr17:3907470 NA 0.58 6.7 0.34 8.57e-11 Type 2 diabetes; LIHC cis rs11786130 1.000 rs11786130 chr8:129004975 G/A cg01765152 chr8:129005526 PVT1 -0.3 -6.41 -0.33 4.92e-10 Eosinophil counts;Sum eosinophil basophil counts; LIHC cis rs483180 0.512 rs1163251 chr1:120209755 T/C cg19096424 chr1:120255104 PHGDH -0.62 -7.86 -0.39 5.01e-14 Macular telangiectasia type 2; LIHC cis rs4759375 0.920 rs7298909 chr12:123830939 C/T cg00376283 chr12:123451042 ABCB9 0.49 6.34 0.32 7.29e-10 HDL cholesterol; LIHC cis rs7903847 0.642 rs6584128 chr10:99171926 G/T cg08345082 chr10:99160200 RRP12 0.42 7.34 0.37 1.62e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs9905704 0.647 rs7221274 chr17:57008128 A/G cg05425664 chr17:57184151 TRIM37 -0.44 -6.13 -0.31 2.42e-9 Testicular germ cell tumor; LIHC cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs11792861 0.962 rs11789624 chr9:111796231 T/C cg05043794 chr9:111880884 C9orf5 -0.31 -7.22 -0.36 3.36e-12 Menarche (age at onset); LIHC trans rs2727020 0.734 rs1164663 chr11:49294723 A/T cg18944383 chr4:111397179 ENPEP -0.31 -6.98 -0.35 1.57e-11 Coronary artery disease; LIHC cis rs9309473 0.847 rs4547554 chr2:73867862 G/C cg20560298 chr2:73613845 ALMS1 -0.55 -6.48 -0.33 3.25e-10 Metabolite levels; LIHC cis rs75908454 1.000 rs78272531 chr6:169808112 G/A cg19338460 chr6:170058176 WDR27 -0.83 -7.52 -0.38 4.91e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs2710642 0.611 rs6749020 chr2:62861957 G/A cg17519650 chr2:63277830 OTX1 0.47 6.88 0.35 2.81e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs7584330 0.554 rs116656801 chr2:238431257 A/G cg08992911 chr2:238395768 MLPH 0.52 6.17 0.32 1.91e-9 Prostate cancer; LIHC cis rs1005277 0.579 rs11011461 chr10:38431427 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2836950 0.545 rs8132143 chr21:40584258 A/T cg06238570 chr21:40685208 BRWD1 -0.43 -7.11 -0.36 6.91e-12 Menarche (age at onset); LIHC cis rs13064411 0.696 rs6783965 chr3:113198722 C/T cg18753928 chr3:113234510 CCDC52 -0.41 -5.79 -0.3 1.57e-8 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs1559088 0.847 rs10423531 chr19:33600140 T/C cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7824557 0.591 rs2736282 chr8:11225480 C/T cg21775007 chr8:11205619 TDH 0.58 8.91 0.43 3.11e-17 Retinal vascular caliber; LIHC cis rs2153535 0.580 rs1115079 chr6:8449615 G/C cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs12477438 0.520 rs11678456 chr2:99708237 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.19 21.29 0.75 1.21e-64 Chronic sinus infection; LIHC cis rs9814567 1.000 rs13089966 chr3:134279197 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1994135 0.692 rs7297538 chr12:33693438 T/C cg26384229 chr12:38710491 ALG10B 0.49 6.56 0.33 1.93e-10 Resting heart rate; LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg00656387 chr3:40428638 ENTPD3 0.5 8.4 0.41 1.22e-15 Renal cell carcinoma; LIHC cis rs999943 0.774 rs10947421 chr6:33611278 G/T cg14003231 chr6:33640908 ITPR3 0.35 7.47 0.37 6.54e-13 Obesity (extreme); LIHC cis rs9303401 0.614 rs12948536 chr17:56580413 G/T cg25039879 chr17:56429692 SUPT4H1 0.74 8.35 0.41 1.7e-15 Cognitive test performance; LIHC cis rs2569991 0.541 rs2596905 chr3:12937672 A/C cg22481960 chr3:13008800 IQSEC1 -0.43 -7.49 -0.38 6.12e-13 Periodontitis (DPAL); LIHC cis rs1580019 0.961 rs4255041 chr7:32496383 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs6952808 0.782 rs4236271 chr7:1881369 C/T cg02951883 chr7:2050386 MAD1L1 -0.48 -7.34 -0.37 1.54e-12 Bipolar disorder and schizophrenia; LIHC cis rs2645694 0.626 rs2703129 chr4:77818548 T/C cg03477792 chr4:77819574 ANKRD56 0.6 8.79 0.43 7.34e-17 Emphysema distribution in smoking; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs7917772 0.582 rs10786698 chr10:104378750 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.87 0.39 4.78e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs8005677 1.000 rs2295683 chr14:23388382 A/C cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs7264396 1.000 rs6060479 chr20:34165723 A/C cg04508476 chr20:34239394 CPNE1;RBM12 0.4 6.78 0.34 5.23e-11 Total cholesterol levels; LIHC cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg24549020 chr5:56110836 MAP3K1 0.48 6.14 0.32 2.29e-9 Initial pursuit acceleration; LIHC cis rs919433 0.648 rs6434933 chr2:198426960 G/A cg10820045 chr2:198174542 NA 0.5 7.88 0.39 4.34e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9549328 0.837 rs9549618 chr13:113628648 G/A cg00071026 chr13:113650936 MCF2L -0.39 -5.9 -0.3 8.55e-9 Systolic blood pressure; LIHC cis rs6893300 0.524 rs12374446 chr5:179131143 A/G cg14593053 chr5:179126677 CANX 0.41 7.54 0.38 4.3e-13 Resting heart rate; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04961397 chr16:30990708 SETD1A 0.43 6.22 0.32 1.49e-9 Longevity; LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg20295408 chr7:1910781 MAD1L1 -0.43 -6.26 -0.32 1.15e-9 Bipolar disorder and schizophrenia; LIHC cis rs11098499 0.731 rs6846966 chr4:120293208 A/G cg09307838 chr4:120376055 NA 0.63 9.49 0.46 4.08e-19 Corneal astigmatism; LIHC trans rs6952407 1 rs6952407 chr7:66045512 A/G cg26939375 chr7:64535504 NA -0.47 -7.23 -0.36 3.08e-12 Cotinine glucuronidation; LIHC cis rs17685 0.753 rs1859791 chr7:75786043 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4660306 0.677 rs781061 chr1:45932887 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC 0.62 6.68 0.34 9.97e-11 Homocysteine levels; LIHC cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg25894440 chr7:65020034 NA -0.52 -6.12 -0.31 2.54e-9 Diabetic kidney disease; LIHC cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg23205692 chr1:25664452 TMEM50A 0.4 6.27 0.32 1.07e-9 Plateletcrit;Mean corpuscular volume; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg16344026 chr5:149109979 PPARGC1B -0.42 -6.51 -0.33 2.74e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1538970 0.962 rs3219463 chr1:45806432 C/T cg05343316 chr1:45956843 TESK2 0.62 8.91 0.43 3.17e-17 Platelet count; LIHC cis rs7584330 0.554 rs76519914 chr2:238429818 G/A cg08992911 chr2:238395768 MLPH 0.55 6.44 0.33 4.12e-10 Prostate cancer; LIHC cis rs270601 0.913 rs273899 chr5:131695178 G/A cg24060327 chr5:131705240 SLC22A5 -0.78 -12.28 -0.55 5.8e-29 Acylcarnitine levels; LIHC cis rs8072100 0.846 rs7214799 chr17:45702099 C/T cg08085267 chr17:45401833 C17orf57 0.38 5.75 0.3 1.96e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs561341 0.714 rs474455 chr17:30312465 A/T cg20587970 chr11:113659929 NA -1.22 -10.56 -0.5 9.63e-23 Hip circumference adjusted for BMI; LIHC cis rs986417 0.901 rs4901987 chr14:60987529 C/T cg27398547 chr14:60952738 C14orf39 0.75 8.1 0.4 9.98e-15 Gut microbiota (bacterial taxa); LIHC cis rs6502050 0.835 rs8065210 chr17:80090960 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.9 -0.3 8.53e-9 Life satisfaction; LIHC cis rs10791097 0.547 rs1050078 chr11:130746146 T/C cg12179176 chr11:130786555 SNX19 0.83 13.79 0.6 1.03e-34 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1043515 0.642 rs8592 chr17:36958065 A/G cg20826740 chr17:37024042 NA 0.34 5.78 0.3 1.72e-8 Height; LIHC trans rs61931739 0.517 rs11612493 chr12:34114272 A/C cg26384229 chr12:38710491 ALG10B 0.5 6.9 0.35 2.57e-11 Morning vs. evening chronotype; LIHC cis rs918629 0.567 rs3777204 chr5:95234350 A/G cg10483112 chr5:95245456 ELL2 -0.37 -6.79 -0.34 5.12e-11 IgG glycosylation; LIHC cis rs10463316 0.832 rs152087 chr5:150734419 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -5.99 -0.31 5.28e-9 Metabolite levels (Pyroglutamine); LIHC cis rs9790314 1.000 rs7653233 chr3:160992033 G/A cg04691961 chr3:161091175 C3orf57 -0.33 -5.71 -0.3 2.41e-8 Morning vs. evening chronotype; LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg06558623 chr16:89946397 TCF25 1.0 15.22 0.64 2.56e-40 Skin colour saturation; LIHC cis rs60871478 0.787 rs4720928 chr7:808002 T/C cg05535760 chr7:792225 HEATR2 0.77 10.79 0.5 1.46e-23 Cerebrospinal P-tau181p levels; LIHC cis rs10508774 1.000 rs11009018 chr10:32939721 G/C cg01819863 chr10:32635814 EPC1 0.64 5.93 0.31 7.24e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7953508 0.750 rs11107119 chr12:93983132 T/A cg18151635 chr12:93972918 NA -0.45 -6.88 -0.35 2.92e-11 Pubertal anthropometrics; LIHC cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs12701220 0.553 rs9639882 chr7:1133731 G/A cg09177884 chr7:1199841 ZFAND2A -0.53 -6.23 -0.32 1.39e-9 Bronchopulmonary dysplasia; LIHC cis rs6701037 0.681 rs2285220 chr1:175130773 T/A cg00958927 chr1:175162553 KIAA0040 -0.4 -6.53 -0.33 2.36e-10 Alcohol dependence; LIHC cis rs6840360 0.967 rs10028961 chr4:152668224 A/G cg22705602 chr4:152727874 NA -0.34 -7.17 -0.36 4.61e-12 Intelligence (multi-trait analysis); LIHC cis rs10870270 1.000 rs3935905 chr10:133758262 A/C cg08754478 chr10:133766260 PPP2R2D -0.55 -8.17 -0.4 5.98e-15 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs9303401 0.614 rs28687626 chr17:57191904 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.95 12.64 0.56 2.48e-30 Cognitive test performance; LIHC cis rs896854 0.517 rs1011796 chr8:95951273 A/G cg23172400 chr8:95962367 TP53INP1 0.35 7.23 0.36 3.14e-12 Type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14875093 chr19:38398164 WDR87;SIPA1L3 0.43 6.85 0.35 3.35e-11 Pancreatic cancer; LIHC cis rs412000 0.507 rs2680688 chr17:56450524 T/C cg10487724 chr17:56770010 TEX14;RAD51C -0.53 -7.45 -0.37 7.87e-13 Primary tooth development (time to first tooth eruption); LIHC cis rs4631830 0.832 rs2611513 chr10:51515457 A/G cg16070123 chr10:51489643 NA 0.38 6.2 0.32 1.58e-9 Prostate-specific antigen levels; LIHC cis rs11098499 0.954 rs12499324 chr4:120393786 C/T cg09307838 chr4:120376055 NA 0.76 12.14 0.55 1.94e-28 Corneal astigmatism; LIHC cis rs12142240 0.692 rs7532149 chr1:46824932 A/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC trans rs1814175 0.754 rs10219245 chr11:49645052 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -22.47 -0.77 2.54e-69 Height; LIHC cis rs929354 0.772 rs3802126 chr7:156970281 G/A cg16102536 chr7:156981717 UBE3C 0.35 5.95 0.31 6.78e-9 Body mass index; LIHC cis rs1789 0.786 rs6449161 chr4:15692954 A/G cg16509355 chr4:15471240 CC2D2A -0.46 -6.95 -0.35 1.89e-11 Blood protein levels; LIHC cis rs796364 0.806 rs1605900 chr2:200870197 C/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.79 8.82 0.43 5.96e-17 Schizophrenia; LIHC trans rs1552244 0.572 rs3894322 chr3:10168965 G/A cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs9733 0.596 rs6692960 chr1:150695965 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.86 8.22 0.41 4.23e-15 Platelet count; LIHC cis rs3806843 0.966 rs2563261 chr5:140137713 G/T cg26395211 chr5:140044315 WDR55 0.4 5.93 0.31 7.44e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03041860 chr2:208489911 FAM119A 0.42 6.36 0.33 6.59e-10 Pancreatic cancer; LIHC cis rs9905704 0.624 rs11652761 chr17:56986095 C/T cg12560992 chr17:57184187 TRIM37 0.68 9.98 0.47 9.65e-21 Testicular germ cell tumor; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.94 0.57 1.95e-31 Prudent dietary pattern; LIHC cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.47 -6.77 -0.34 5.6e-11 Lymphocyte counts; LIHC cis rs7772486 0.658 rs9403737 chr6:145962193 G/T cg23711669 chr6:146136114 FBXO30 0.72 13.18 0.58 2.28e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs10876993 0.928 rs2169988 chr12:58071165 G/A cg15848620 chr12:58087721 OS9 -0.58 -8.02 -0.4 1.65e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs11098499 0.645 rs78422072 chr4:120281042 C/T cg09307838 chr4:120376055 NA 0.63 9.05 0.44 1.07e-17 Corneal astigmatism; LIHC cis rs67478160 0.595 rs1475007 chr14:104297147 A/G cg24130564 chr14:104152367 KLC1 -0.35 -5.79 -0.3 1.61e-8 Schizophrenia; LIHC cis rs644799 0.509 rs561635 chr11:95634232 C/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.49 -6.76 -0.34 6.01e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4845459 0.967 rs4845453 chr1:152591953 C/G cg18116418 chr1:152553244 LCE3D -0.34 -6.27 -0.32 1.06e-9 Psoriasis; LIHC cis rs7582720 1.000 rs6435169 chr2:203753016 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs7772486 0.754 rs697055 chr6:146003790 C/G cg23711669 chr6:146136114 FBXO30 0.71 12.26 0.55 7.09e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs10197940 0.662 rs1047957 chr2:152333773 C/T cg19508488 chr2:152266495 RIF1 0.55 7.76 0.39 9.78e-14 Lung cancer; LIHC cis rs6445975 0.715 rs6809809 chr3:58267950 A/G cg23715586 chr3:58305044 RPP14 -0.37 -6.24 -0.32 1.31e-9 Systemic lupus erythematosus; LIHC trans rs72829446 0.530 rs111259369 chr17:7383082 C/T cg08566640 chr11:64091735 NA -0.67 -6.13 -0.31 2.36e-9 Androgen levels; LIHC trans rs1814175 0.645 rs11040661 chr11:49952146 G/T cg18944383 chr4:111397179 ENPEP 0.27 6.82 0.35 4.17e-11 Height; LIHC cis rs34779708 0.897 rs4934527 chr10:35281118 T/A cg03585969 chr10:35415529 CREM 0.85 12.85 0.57 4.32e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1385374 0.858 rs3741615 chr12:129298848 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.75 0.39 1.09e-13 Systemic lupus erythematosus; LIHC cis rs2933343 0.621 rs789242 chr3:128585707 T/C cg24203234 chr3:128598194 ACAD9 0.44 6.03 0.31 4.17e-9 IgG glycosylation; LIHC cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg01448562 chr3:133502909 NA -0.43 -6.87 -0.35 3.13e-11 Iron status biomarkers; LIHC cis rs17253792 0.822 rs10149408 chr14:56046075 G/A cg24579896 chr14:56047964 C14orf33;KTN1 0.7 5.82 0.3 1.38e-8 Putamen volume; LIHC cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg11764359 chr7:65958608 NA 0.58 6.06 0.31 3.57e-9 Diabetic kidney disease; LIHC cis rs796364 0.806 rs1106400 chr2:201004089 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.54 -6.15 -0.32 2.16e-9 Schizophrenia; LIHC cis rs34779708 0.931 rs4934724 chr10:35393669 C/T cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7039377 0.541 rs7850196 chr9:38671574 G/T cg14625731 chr9:38672608 NA -0.48 -8.97 -0.44 1.99e-17 Obesity-related traits; LIHC cis rs1008375 0.863 rs10003291 chr4:17600728 A/C cg02297831 chr4:17616191 MED28 0.41 5.77 0.3 1.76e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7572733 0.534 rs700670 chr2:198687284 T/C cg00792783 chr2:198669748 PLCL1 0.45 6.7 0.34 8.84e-11 Dermatomyositis; LIHC trans rs911555 0.723 rs56227024 chr14:103861706 A/G cg17675199 chr6:35436792 RPL10A -0.38 -7.68 -0.38 1.65e-13 Intelligence (multi-trait analysis); LIHC cis rs12824058 0.831 rs55726136 chr12:130810312 G/A cg24838063 chr12:130822603 PIWIL1 0.67 9.96 0.47 1.1e-20 Menopause (age at onset); LIHC cis rs6882046 0.513 rs625970 chr5:88042296 A/G cg22951263 chr5:87985283 NA -0.39 -6.74 -0.34 6.86e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs4934494 0.727 rs12764076 chr10:91390200 T/C cg19698084 chr10:91461284 KIF20B -0.46 -6.19 -0.32 1.74e-9 Red blood cell count; LIHC cis rs10423674 0.526 rs34482977 chr19:18824038 C/G cg14292368 chr19:18793705 CRTC1 -0.42 -5.82 -0.3 1.34e-8 Menarche (age at onset); LIHC cis rs910316 0.737 rs175071 chr14:75498177 A/G cg08847533 chr14:75593920 NEK9 -0.89 -18.4 -0.71 4.82e-53 Height; LIHC cis rs3862030 0.694 rs2025712 chr10:104230064 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.27 -0.37 2.42e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs4555082 0.874 rs2245329 chr14:105719181 T/C cg10792982 chr14:105748885 BRF1 0.45 6.18 0.32 1.85e-9 Mean platelet volume;Platelet distribution width; LIHC trans rs743793 0.875 rs137381 chr22:33578402 C/T cg20274824 chr1:36638199 MAP7D1 0.46 6.42 0.33 4.66e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg10360139 chr7:1886902 MAD1L1 0.42 6.48 0.33 3.12e-10 Bipolar disorder and schizophrenia; LIHC cis rs1801251 0.778 rs2592115 chr2:233736349 C/T cg08000102 chr2:233561755 GIGYF2 -0.71 -10.76 -0.5 1.88e-23 Coronary artery disease; LIHC cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg05025164 chr4:1340916 KIAA1530 -0.66 -9.96 -0.47 1.09e-20 Obesity-related traits; LIHC cis rs12950390 0.893 rs4239165 chr17:45847272 A/T cg03474202 chr17:45855739 NA -0.34 -5.99 -0.31 5.29e-9 IgG glycosylation; LIHC cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg13047869 chr3:10149882 C3orf24 0.52 6.18 0.32 1.81e-9 Alzheimer's disease; LIHC cis rs477895 0.713 rs2282490 chr11:63962152 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 9.65 0.46 1.17e-19 Mean platelet volume; LIHC trans rs75804782 0.641 rs72987321 chr2:239352765 T/G cg01134436 chr17:81009848 B3GNTL1 0.8 6.64 0.34 1.27e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs1577917 1.000 rs12213740 chr6:86656733 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.29 -0.49 8.14e-22 Response to antipsychotic treatment; LIHC cis rs911119 0.955 rs8115423 chr20:23605253 T/C cg16589663 chr20:23618590 CST3 0.76 8.04 0.4 1.44e-14 Chronic kidney disease; LIHC cis rs12188164 0.543 rs890972 chr5:462465 C/A cg16584290 chr5:462447 EXOC3 0.37 6.03 0.31 4.14e-9 Cystic fibrosis severity; LIHC cis rs9918079 0.560 rs7685083 chr4:15610771 G/A cg24225360 chr4:15471699 CC2D2A 0.39 6.2 0.32 1.67e-9 Obesity-related traits; LIHC cis rs6088813 1.000 rs6142373 chr20:33983314 T/A cg14752227 chr20:34000481 UQCC -0.4 -5.75 -0.3 1.99e-8 Height; LIHC cis rs4362 0.934 rs4343 chr17:61566031 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.38 5.9 0.3 8.6e-9 Blood metabolite levels; LIHC cis rs3806843 1.000 rs4151680 chr5:140186657 A/G cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs1347297 0.590 rs9288019 chr2:179276894 C/A cg14011486 chr1:26737247 LIN28 0.63 10.04 0.48 5.75e-21 Alzheimer disease and age of onset; LIHC cis rs986417 1.000 rs10149915 chr14:60943110 G/A cg27398547 chr14:60952738 C14orf39 0.81 9.39 0.45 8.69e-19 Gut microbiota (bacterial taxa); LIHC cis rs12477438 0.822 rs6727170 chr2:99588042 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.73 -8.37 -0.41 1.45e-15 Chronic sinus infection; LIHC cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.83 0.57 4.9e-31 Alzheimer's disease; LIHC cis rs72781680 1.000 rs74704838 chr2:24158270 C/A cg08917208 chr2:24149416 ATAD2B 0.84 7.73 0.39 1.21e-13 Lymphocyte counts; LIHC trans rs2797160 0.515 rs4897149 chr6:125980018 G/T cg05039488 chr6:79577232 IRAK1BP1 0.41 6.11 0.31 2.7e-9 Endometrial cancer; LIHC trans rs12478296 0.591 rs6746311 chr2:243001279 A/G cg01596870 chr19:55963115 NA -0.68 -10.23 -0.48 1.34e-21 Obesity-related traits; LIHC trans rs11098499 0.863 rs10019674 chr4:120443489 C/T cg25214090 chr10:38739885 LOC399744 -0.6 -9.76 -0.47 5.03e-20 Corneal astigmatism; LIHC cis rs911119 0.955 rs6048945 chr20:23602228 C/T cg16589663 chr20:23618590 CST3 0.74 7.78 0.39 8.48e-14 Chronic kidney disease; LIHC cis rs807029 0.577 rs11190787 chr10:102758625 G/T cg27255678 chr10:102756921 LZTS2 0.51 7.17 0.36 4.56e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7412746 0.611 rs1889740 chr1:150799755 C/T cg18016565 chr1:150552671 MCL1 0.5 9.62 0.46 1.5700000000000001e-19 Melanoma; LIHC cis rs7223966 1.000 rs8078462 chr17:61857937 T/G cg05941027 chr17:61774174 LIMD2 0.35 7.35 0.37 1.48e-12 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs2832077 0.824 rs4816333 chr21:30201777 C/G cg14791747 chr16:20752902 THUMPD1 0.49 6.34 0.32 7.26e-10 Cognitive test performance; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02902865 chr1:12679132 DHRS3 0.47 6.89 0.35 2.76e-11 Pancreatic cancer; LIHC cis rs8084351 0.577 rs8089270 chr18:50639779 G/A cg24270629 chr18:50823537 DCC 0.42 6.25 0.32 1.21e-9 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg03188948 chr7:1209495 NA 0.8 5.97 0.31 5.98e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1190552 0.846 rs11623570 chr14:102959277 G/T cg10241871 chr14:102965420 TECPR2 -0.48 -7.81 -0.39 6.95e-14 Blood protein levels; LIHC cis rs929354 0.772 rs1182438 chr7:157027438 G/A cg17757837 chr7:157058334 UBE3C -0.72 -11.77 -0.54 4.33e-27 Body mass index; LIHC cis rs1371867 0.875 rs1788173 chr8:101330939 A/G cg06636551 chr8:101224915 SPAG1 0.47 8.95 0.44 2.38e-17 Atrioventricular conduction; LIHC cis rs6690583 0.623 rs12042845 chr1:85429801 A/G cg22153463 chr1:85462885 MCOLN2 0.52 6.13 0.31 2.4e-9 Serum sulfate level; LIHC cis rs6952808 0.564 rs73038441 chr7:2139286 T/C cg04267008 chr7:1944627 MAD1L1 -0.53 -8.35 -0.41 1.69e-15 Bipolar disorder and schizophrenia; LIHC cis rs2303759 1.000 rs2303759 chr19:49869051 T/G cg24324837 chr19:49891574 CCDC155 0.39 6.16 0.32 2.05e-9 Multiple sclerosis; LIHC cis rs2576037 0.623 rs2576042 chr18:44577461 T/C cg19077165 chr18:44547161 KATNAL2 0.49 7.27 0.37 2.43e-12 Personality dimensions; LIHC cis rs6500602 0.727 rs4238849 chr16:4538114 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.48 7.5 0.38 5.64e-13 Schizophrenia; LIHC cis rs797680 0.856 rs7553465 chr1:93644410 C/T cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.88 -0.3 9.71e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs3888647 0.622 rs4758618 chr11:2995186 A/T cg20651018 chr11:3035856 CARS -0.35 -5.98 -0.31 5.6e-9 Type 2 diabetes; LIHC cis rs2559856 1.000 rs2695298 chr12:102082589 G/A cg12924262 chr12:102091054 CHPT1 0.49 7.83 0.39 6.22e-14 Blood protein levels; LIHC cis rs11690935 0.959 rs3770452 chr2:172668682 A/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.64 -0.69 5.32e-50 Schizophrenia; LIHC cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs929354 0.772 rs3802126 chr7:156970281 G/A cg05182265 chr7:156933206 UBE3C -0.31 -5.88 -0.3 9.8e-9 Body mass index; LIHC cis rs9378688 0.546 rs2479014 chr6:2357948 C/T cg12303981 chr6:2244766 GMDS -0.45 -6.46 -0.33 3.62e-10 Caudate nucleus volume; LIHC cis rs344364 0.511 rs1742463 chr16:1946110 A/G cg26897989 chr16:1907736 C16orf73 -0.46 -5.77 -0.3 1.82e-8 Glomerular filtration rate in chronic kidney disease; LIHC cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg04267008 chr7:1944627 MAD1L1 -0.68 -10.74 -0.5 2.15e-23 Bipolar disorder and schizophrenia; LIHC cis rs12950390 0.893 rs72831644 chr17:45824391 T/C cg03474202 chr17:45855739 NA -0.36 -6.19 -0.32 1.7e-9 IgG glycosylation; LIHC cis rs611744 0.870 rs634216 chr8:109174803 A/G cg18478394 chr8:109455254 TTC35 0.42 7.05 0.36 9.74e-12 Dupuytren's disease; LIHC cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs921968 0.541 rs561570 chr2:219379348 T/A cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs473651 0.904 rs508274 chr2:239337723 G/A cg21699342 chr2:239360505 ASB1 0.34 6.57 0.33 1.91e-10 Multiple system atrophy; LIHC cis rs7923837 0.683 rs11187078 chr10:94340705 C/G cg25506282 chr10:94462361 NA 0.35 5.92 0.31 7.64e-9 Body mass index;Multiple sclerosis; LIHC trans rs2359714 0.935 rs10494208 chr1:118796777 A/T cg19861078 chr7:7936962 NA 0.32 6.19 0.32 1.73e-9 Breast size; LIHC trans rs1864585 0.520 rs17776622 chr8:10676497 T/C cg26278703 chr11:58910052 FAM111A 0.73 6.32 0.32 8.11e-10 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs7633770 0.786 rs9845998 chr3:46683710 G/A cg11219411 chr3:46661640 NA 0.45 8.08 0.4 1.12e-14 Coronary artery disease; LIHC cis rs11122272 0.735 rs2491403 chr1:231511185 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg06969265 chr17:73775802 H3F3B 0.68 6.13 0.31 2.45e-9 Psoriasis; LIHC cis rs6952808 0.929 rs2280550 chr7:1976556 G/A cg02951883 chr7:2050386 MAD1L1 -0.65 -10.33 -0.49 6.14e-22 Bipolar disorder and schizophrenia; LIHC cis rs9660992 0.573 rs12140422 chr1:205187981 G/A cg21545522 chr1:205238299 TMCC2 0.37 7.15 0.36 5.22e-12 Mean corpuscular volume;Mean platelet volume; LIHC trans rs11638815 0.626 rs1313492 chr15:83272955 A/G cg18393722 chr15:85113863 UBE2QP1 -0.36 -6.06 -0.31 3.66e-9 Lipoprotein-associated phospholipase A2 activity change in response to statin therapy; LIHC trans rs5756813 0.688 rs2413483 chr22:38127950 C/T cg19894588 chr14:64061835 NA -0.61 -7.78 -0.39 8.85e-14 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg10802521 chr3:52805072 NEK4 -0.43 -7.18 -0.36 4.25e-12 Bipolar disorder; LIHC cis rs6088580 0.524 rs6087612 chr20:33230822 T/G cg08999081 chr20:33150536 PIGU -0.43 -7.38 -0.37 1.2e-12 Glomerular filtration rate (creatinine); LIHC cis rs11764590 0.813 rs11768212 chr7:1992582 A/C cg23422044 chr7:1970798 MAD1L1 -0.61 -6.55 -0.33 2.13e-10 Neuroticism; LIHC cis rs17685 0.753 rs3757593 chr7:75678735 G/A cg04592579 chr7:75616294 TMEM120A -0.4 -6.83 -0.35 3.8e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1552244 0.554 rs2272119 chr3:10049352 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -7.97 -0.4 2.43e-14 Alzheimer's disease; LIHC cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg06212747 chr3:49208901 KLHDC8B 0.65 8.9 0.43 3.38e-17 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs1580019 0.587 rs34488151 chr7:32548146 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.16 0.44 4.82e-18 Cognitive ability; LIHC cis rs11662586 1.000 rs7243921 chr18:77695237 G/A cg20368463 chr18:77673604 PQLC1 0.42 6.65 0.34 1.13e-10 Exploratory eye movement dysfunction in schizophrenia (responsive search score); LIHC cis rs5753618 0.583 rs5753639 chr22:31870400 A/G cg02404636 chr22:31891804 SFI1 -0.35 -6.26 -0.32 1.15e-9 Colorectal cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg13792025 chr7:66205470 RABGEF1 -0.47 -6.15 -0.32 2.16e-9 Systolic blood pressure; LIHC cis rs614226 1.000 rs1614223 chr12:120964043 T/C cg01236616 chr12:121019343 POP5 1.25 19.27 0.72 1.53e-56 Type 1 diabetes nephropathy; LIHC cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.19 11.6 0.53 1.85e-26 Platelet count; LIHC cis rs7520050 0.966 rs6662641 chr1:46571509 T/A cg03146154 chr1:46216737 IPP -0.38 -6.25 -0.32 1.22e-9 Red blood cell count;Reticulocyte count; LIHC cis rs875971 0.928 rs2036263 chr7:65800197 C/T cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.07e-40 Aortic root size; LIHC cis rs9896933 0.623 rs77166830 chr17:80833525 T/C cg20578329 chr17:80767326 TBCD -0.67 -6.34 -0.32 7.38e-10 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs367615 0.918 rs4270746 chr5:108876839 T/C cg17395555 chr5:108820864 NA 0.34 6.97 0.35 1.65e-11 Colorectal cancer (SNP x SNP interaction); LIHC cis rs12579753 1.000 rs11115030 chr12:82203021 A/T cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC cis rs734999 0.505 rs4278312 chr1:2539555 A/G cg18854424 chr1:2615690 NA 0.33 7.38 0.37 1.19e-12 Ulcerative colitis; LIHC cis rs4746818 1.000 rs10998614 chr10:70923347 G/T cg11621586 chr10:70884670 VPS26A 0.87 14.21 0.61 2.47e-36 Left atrial antero-posterior diameter; LIHC cis rs9326778 0.520 rs4957819 chr5:108829195 C/T cg17395555 chr5:108820864 NA 0.35 6.0 0.31 4.96e-9 Aggressiveness in attention deficit hyperactivity disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22146484 chr8:57123862 CHCHD7;PLAG1 0.45 6.66 0.34 1.06e-10 Pancreatic cancer; LIHC cis rs7552404 1.000 rs4949674 chr1:76213715 C/A cg03433033 chr1:76189801 ACADM 0.65 9.18 0.44 4.29e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs17102423 0.531 rs2763888 chr14:65571493 T/C cg16583315 chr14:65563665 MAX -0.41 -8.41 -0.41 1.13e-15 Obesity-related traits; LIHC cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg22528358 chr1:107598549 PRMT6 0.69 11.37 0.52 1.26e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4950322 0.576 rs2353980 chr1:146839989 A/T cg25205988 chr1:146714368 CHD1L 0.44 6.16 0.32 1.99e-9 Protein quantitative trait loci; LIHC cis rs4689592 0.503 rs11945642 chr4:7051065 G/C cg26116260 chr4:7069785 GRPEL1 -0.97 -17.16 -0.68 4.9e-48 Monocyte percentage of white cells; LIHC cis rs2282526 0.615 rs162377 chr21:44926001 A/G cg04455712 chr21:45112962 RRP1B 0.45 7.42 0.37 9.55e-13 Mean corpuscular hemoglobin; LIHC cis rs7100689 0.577 rs9285726 chr10:82035150 A/T cg00277334 chr10:82204260 NA -0.5 -5.9 -0.3 8.6e-9 Post bronchodilator FEV1; LIHC cis rs11761441 1.000 rs12718067 chr7:82873 T/C cg25149888 chr7:81075 NA 0.3 7.07 0.36 8.72e-12 Alzheimer's disease in APOE e4- carriers; LIHC cis rs17401966 1.000 rs3748578 chr1:10420918 A/G cg15208524 chr1:10270712 KIF1B -0.44 -6.3 -0.32 9.19e-10 Hepatocellular carcinoma; LIHC cis rs317689 0.819 rs317685 chr12:69715457 A/G cg20891283 chr12:69753455 YEATS4 -0.56 -8.3 -0.41 2.43e-15 Response to diuretic therapy; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg05484376 chr2:27715224 FNDC4 0.38 6.59 0.34 1.67e-10 Total body bone mineral density; LIHC cis rs13064411 0.696 rs6766615 chr3:113219342 T/C cg18753928 chr3:113234510 CCDC52 -0.44 -6.3 -0.32 9.3e-10 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg06873352 chr17:61820015 STRADA 0.6 9.32 0.45 1.47e-18 Height; LIHC trans rs4924935 0.509 rs8074020 chr17:18801380 T/C cg21372672 chr17:16614065 CCDC144A -0.26 -6.35 -0.32 6.79e-10 Pancreatic cancer; LIHC cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg04083430 chr16:4736063 MGRN1 0.4 5.72 0.3 2.38e-8 Schizophrenia; LIHC cis rs1801251 1.000 rs283484 chr2:233646505 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.36 0.52 1.37e-25 Coronary artery disease; LIHC cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg06481639 chr22:41940642 POLR3H 0.62 6.53 0.33 2.45e-10 Vitiligo; LIHC cis rs7829975 0.617 rs4841071 chr8:8791144 G/T cg06636001 chr8:8085503 FLJ10661 0.38 6.17 0.32 1.9e-9 Mood instability; LIHC cis rs67478160 0.595 rs67768834 chr14:104221085 C/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.68 0.57 1.8e-30 Schizophrenia; LIHC cis rs2832191 0.716 rs1543652 chr21:30448000 G/C cg24692254 chr21:30365293 RNF160 0.87 15.64 0.65 5.61e-42 Dental caries; LIHC cis rs2859741 1.000 rs543121 chr1:37497098 T/C cg09363841 chr1:37513479 NA -0.2 -6.28 -0.32 1.05e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC trans rs801193 0.591 rs9986881 chr7:66173040 A/G cg26939375 chr7:64535504 NA 0.46 7.88 0.39 4.31e-14 Aortic root size; LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.46 7.75 0.39 1.06e-13 Height; LIHC cis rs769267 0.895 rs2315279 chr19:19479936 C/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.53 -8.13 -0.4 8.08e-15 Tonsillectomy; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg07677032 chr17:61819896 STRADA -0.41 -5.94 -0.31 6.89e-9 Prudent dietary pattern; LIHC cis rs15676 1.000 rs10988125 chr9:131572903 A/G cg00228799 chr9:131580591 ENDOG 0.45 6.74 0.34 6.65e-11 Blood metabolite levels; LIHC cis rs7772486 0.686 rs2072911 chr6:146056801 G/A cg23711669 chr6:146136114 FBXO30 -0.62 -11.25 -0.52 3.48e-25 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07549551 chr6:158487608 SYNJ2 -0.47 -6.95 -0.35 1.84e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs5769707 0.521 rs6009810 chr22:50059540 A/G cg07959070 chr22:50026188 C22orf34 -0.29 -6.88 -0.35 2.92e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg21280719 chr6:42927975 GNMT -0.36 -7.84 -0.39 5.77e-14 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs1814175 0.645 rs7928714 chr11:49887622 G/A cg03929089 chr4:120376271 NA -0.83 -15.84 -0.65 8.89e-43 Height; LIHC trans rs4596713 0.508 rs12056979 chr9:71778946 A/G cg16512924 chr15:28394682 HERC2 0.39 6.25 0.32 1.21e-9 Headache; LIHC cis rs12477438 0.765 rs10181344 chr2:99692829 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.54 -0.38 4.32e-13 Chronic sinus infection; LIHC cis rs12477438 0.520 rs6542866 chr2:99764592 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.13 0.61 5.14e-36 Chronic sinus infection; LIHC cis rs7582180 0.629 rs11678148 chr2:100966950 A/T cg14675211 chr2:100938903 LONRF2 0.55 8.61 0.42 2.78e-16 Intelligence (multi-trait analysis); LIHC cis rs9921222 0.509 rs3743883 chr16:404750 T/C cg12437481 chr16:420112 MRPL28 -0.51 -7.71 -0.38 1.36e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs4900538 0.821 rs12586673 chr14:102827643 C/T cg18135206 chr14:102964638 TECPR2 -0.69 -10.25 -0.48 1.09e-21 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs4714291 0.963 rs2475496 chr6:39963850 A/G cg16345906 chr6:40101885 NA -0.29 -5.73 -0.3 2.23e-8 Strep throat; LIHC cis rs703842 0.616 rs4760171 chr12:58225904 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.64 8.93 0.43 2.7e-17 Multiple sclerosis; LIHC cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg26818010 chr10:134567672 INPP5A -0.72 -9.19 -0.44 3.93e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6429082 0.634 rs3856245 chr1:235571428 G/A cg26050004 chr1:235667680 B3GALNT2 -0.46 -6.85 -0.35 3.49e-11 Adiposity; LIHC cis rs79387448 0.745 rs76720903 chr2:103162826 G/A cg09003973 chr2:102972529 NA 0.88 7.62 0.38 2.44e-13 Gut microbiota (bacterial taxa); LIHC cis rs2576037 0.526 rs2187092 chr18:44526798 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 10.89 0.51 6.32e-24 Personality dimensions; LIHC cis rs1003719 0.715 rs2212742 chr21:38578685 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg18305652 chr10:134549665 INPP5A 0.44 6.47 0.33 3.38e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs921968 0.643 rs645796 chr2:219389236 A/G cg17980119 chr2:219472607 PLCD4 0.35 6.05 0.31 3.84e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs4808199 0.895 rs6511036 chr19:19582651 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.43 6.08 0.31 3.29e-9 Nonalcoholic fatty liver disease; LIHC cis rs12220238 0.841 rs12098284 chr10:76047464 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.35 0.32 6.83e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs12477438 0.501 rs12613624 chr2:99732741 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.62 -10.0 -0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs1881396 0.945 rs62141291 chr2:27784034 C/T cg27432699 chr2:27873401 GPN1 0.46 6.76 0.34 6.12e-11 Nonalcoholic fatty liver disease; LIHC trans rs208520 0.526 rs9363522 chr6:66816642 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.04 -20.62 -0.74 5.92e-62 Exhaled nitric oxide output; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg24693881 chr1:107596107 NA 0.56 9.84 0.47 2.83e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs853679 0.517 rs4713152 chr6:28137454 G/A cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs826838 0.935 rs3886109 chr12:39189243 C/T cg13010199 chr12:38710504 ALG10B 0.5 6.02 0.31 4.6e-9 Heart rate; LIHC cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg12386194 chr3:101231763 SENP7 0.46 6.76 0.34 6.11e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs28647808 0.881 rs28622217 chr9:136267323 A/G cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs6840360 0.967 rs6823423 chr4:152604723 T/C cg22705602 chr4:152727874 NA -0.31 -6.45 -0.33 3.82e-10 Intelligence (multi-trait analysis); LIHC cis rs12464559 0.649 rs10754989 chr2:152642235 T/C cg01189475 chr2:152685088 ARL5A 0.64 7.38 0.37 1.19e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.16 0.55 1.58e-28 Prudent dietary pattern; LIHC cis rs7412746 0.611 rs2271076 chr1:150916657 C/T cg15448220 chr1:150897856 SETDB1 0.39 6.25 0.32 1.22e-9 Melanoma; LIHC cis rs3106136 0.872 rs10030713 chr4:95238536 C/G cg11021082 chr4:95130006 SMARCAD1 -0.38 -6.67 -0.34 1e-10 Capecitabine sensitivity; LIHC cis rs875971 0.964 rs778735 chr7:65814809 C/A cg18876405 chr7:65276391 NA 0.36 6.58 0.34 1.73e-10 Aortic root size; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg00908189 chr16:619842 PIGQ 0.81 13.58 0.59 6.95e-34 Height; LIHC cis rs1062177 0.826 rs2053063 chr5:151166764 T/C cg00977110 chr5:151150581 G3BP1 0.55 6.98 0.35 1.56e-11 Preschool internalizing problems; LIHC cis rs6089584 0.830 rs6089309 chr20:60585687 T/C cg06108461 chr20:60628389 TAF4 -0.91 -13.92 -0.6 3.42e-35 Body mass index; LIHC cis rs6964587 0.839 rs10236107 chr7:91485461 G/A cg17063962 chr7:91808500 NA -0.98 -18.24 -0.7 2.17e-52 Breast cancer; LIHC cis rs11098499 0.663 rs28369503 chr4:120238925 G/A cg09307838 chr4:120376055 NA 0.72 11.19 0.52 5.63e-25 Corneal astigmatism; LIHC cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.63 0.53 1.49e-26 Alzheimer's disease; LIHC cis rs1707322 1.000 rs4660905 chr1:46461587 C/T cg03146154 chr1:46216737 IPP -0.48 -7.76 -0.39 9.96e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2180341 1.000 rs2144743 chr6:127633810 A/T cg24812749 chr6:127587940 RNF146 1.07 16.09 0.66 9.4e-44 Breast cancer; LIHC cis rs703842 1.000 rs6581155 chr12:58178162 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.8 13.28 0.58 9.82e-33 Multiple sclerosis; LIHC cis rs472402 0.580 rs11738248 chr5:6657494 C/T cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.47 -5.8 -0.3 1.49e-8 Response to amphetamines; LIHC cis rs67460515 0.892 rs34896809 chr3:161059804 C/T cg17135325 chr3:160939158 NMD3 0.56 8.25 0.41 3.54e-15 Parkinson's disease; LIHC cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg19774624 chr17:42201019 HDAC5 0.83 12.81 0.57 6.02e-31 Total body bone mineral density; LIHC cis rs4759375 0.667 rs11057242 chr12:123770362 T/C cg00376283 chr12:123451042 ABCB9 -0.49 -6.32 -0.32 8.36e-10 HDL cholesterol; LIHC cis rs736408 0.812 rs2071507 chr3:52826707 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.43 6.76 0.34 5.83e-11 Bipolar disorder; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25631714 chr4:68566961 LOC550112;UBA6 -0.56 -6.54 -0.33 2.18e-10 Systolic blood pressure; LIHC cis rs807669 0.933 rs712959 chr22:19159015 C/T cg02655711 chr22:19163373 SLC25A1 0.44 8.45 0.42 8.54e-16 Metabolite levels; LIHC cis rs2658782 0.507 rs4457713 chr11:93037430 C/T cg15737290 chr11:93063684 CCDC67 0.46 6.09 0.31 3.11e-9 Pulmonary function decline; LIHC cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg18252515 chr7:66147081 NA -1.25 -16.52 -0.67 1.7e-45 Diabetic kidney disease; LIHC cis rs7760535 0.656 rs1883136 chr6:111907023 G/T cg22127309 chr6:111907043 TRAF3IP2 -0.35 -7.14 -0.36 5.72e-12 Metabolic traits; LIHC trans rs62103177 0.810 rs62103189 chr18:77627815 G/A cg05926928 chr17:57297772 GDPD1 1.11 11.42 0.53 8.64e-26 Opioid sensitivity; LIHC cis rs6831352 0.918 rs29001209 chr4:100052340 C/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs9814567 1.000 rs9289476 chr3:134237103 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12144094 0.882 rs11577560 chr1:120229865 A/G cg20995928 chr1:120229863 NA 0.43 7.48 0.37 6.52e-13 Height; LIHC cis rs7089973 0.604 rs1359079 chr10:116582502 A/G cg03647239 chr10:116582469 FAM160B1 0.44 6.47 0.33 3.49e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs829883 0.624 rs829881 chr12:98881228 T/G cg23471612 chr12:98897216 NA 0.31 5.94 0.31 7e-9 Colorectal adenoma (advanced); LIHC trans rs1814175 0.527 rs3974435 chr11:49619533 G/A cg15704280 chr7:45808275 SEPT13 -0.78 -11.72 -0.54 6.83e-27 Height; LIHC cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg21724239 chr8:58056113 NA 0.48 6.4 0.33 5.2400000000000005e-10 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg11890956 chr21:40555474 PSMG1 1.08 15.48 0.64 2.54e-41 Cognitive function; LIHC cis rs1552244 0.515 rs7613004 chr3:9999913 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.87 0.39 4.59e-14 Alzheimer's disease; LIHC cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 10.56 0.5 9.32e-23 Platelet count; LIHC cis rs57221529 0.766 rs72706610 chr5:561111 G/A cg09021430 chr5:549028 NA -0.45 -9.09 -0.44 8.22e-18 Lung disease severity in cystic fibrosis; LIHC cis rs7772486 0.558 rs2142978 chr6:146012061 T/C cg05347473 chr6:146136440 FBXO30 -0.45 -6.64 -0.34 1.22e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.859 rs62149714 chr2:61603869 T/G cg15711740 chr2:61764176 XPO1 0.42 5.74 0.3 2.14e-8 Tuberculosis; LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs4665809 1.000 rs2384323 chr2:26306473 C/T cg04944784 chr2:26401820 FAM59B -0.65 -8.36 -0.41 1.61e-15 Gut microbiome composition (summer); LIHC trans rs10827565 1.000 rs10827565 chr10:36244409 C/G cg12960782 chr5:59996455 DEPDC1B -0.53 -6.07 -0.31 3.39e-9 Bronchial neuroendocrine tumor; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg02656525 chr5:110427854 WDR36 0.43 6.29 0.32 9.74e-10 Calcium levels; LIHC cis rs929354 0.772 rs1182362 chr7:157019535 A/G cg16102536 chr7:156981717 UBE3C -0.36 -6.11 -0.31 2.77e-9 Body mass index; LIHC cis rs7100689 0.784 rs3120977 chr10:82075324 C/G cg01528321 chr10:82214614 TSPAN14 0.87 11.96 0.54 8.55e-28 Post bronchodilator FEV1; LIHC cis rs796364 0.806 rs74771155 chr2:200913743 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs4665809 1.000 rs13030858 chr2:26315451 G/A cg04944784 chr2:26401820 FAM59B -0.66 -8.33 -0.41 2.02e-15 Gut microbiome composition (summer); LIHC cis rs7582720 0.943 rs72934551 chr2:203984117 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg15534755 chr11:117069859 TAGLN -0.37 -6.23 -0.32 1.37e-9 Blood protein levels; LIHC cis rs986417 0.901 rs7159628 chr14:61010688 A/C cg27398547 chr14:60952738 C14orf39 0.74 8.02 0.4 1.71e-14 Gut microbiota (bacterial taxa); LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg01516881 chr6:292596 DUSP22 -0.5 -6.35 -0.32 7.01e-10 Menopause (age at onset); LIHC cis rs763014 0.932 rs35067229 chr16:649638 T/C cg08989290 chr16:615782 NHLRC4 0.31 6.12 0.31 2.57e-9 Height; LIHC cis rs11734570 0.581 rs73811716 chr4:38590773 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.53 7.23 0.36 3.18e-12 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3806843 0.900 rs2261651 chr5:140136804 A/C cg19875535 chr5:140030758 IK -0.36 -5.89 -0.3 9.44e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs317689 0.690 rs604168 chr12:69671158 C/T cg14784868 chr12:69753453 YEATS4 0.56 7.95 0.39 2.73e-14 Response to diuretic therapy; LIHC cis rs523522 0.962 rs651627 chr12:121009198 C/T cg27279351 chr12:120934652 DYNLL1 0.66 11.76 0.54 5e-27 High light scatter reticulocyte count; LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.81 -0.3 1.42e-8 Menopause (age at onset); LIHC cis rs10911232 0.507 rs10911194 chr1:182993025 C/T ch.1.3577855R chr1:183094577 LAMC1 0.59 10.25 0.48 1.08e-21 Hypertriglyceridemia; LIHC cis rs7772486 0.754 rs6910790 chr6:146255330 G/A cg23711669 chr6:146136114 FBXO30 -0.64 -11.11 -0.52 1.04e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs79149102 0.579 rs74023935 chr15:75359184 T/C cg17294928 chr15:75287854 SCAMP5 -0.5 -6.29 -0.32 9.46e-10 Lung cancer; LIHC cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.63 0.34 1.34e-10 Bipolar disorder; LIHC cis rs11098499 0.691 rs2136911 chr4:120265859 G/A cg09307838 chr4:120376055 NA 0.63 9.88 0.47 2.07e-20 Corneal astigmatism; LIHC cis rs7605378 0.658 rs4673507 chr2:200710167 G/C cg23649088 chr2:200775458 C2orf69 0.52 7.89 0.39 4.1e-14 Osteoporosis; LIHC cis rs10883723 0.810 rs7092622 chr10:104249919 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.76 0.57 9.25e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs2737618 0.651 rs2249172 chr1:200082955 A/G cg21825944 chr1:200113062 NR5A2 0.39 6.84 0.35 3.65e-11 Uric acid levels; LIHC cis rs8067354 0.645 rs72840522 chr17:57829992 G/A cg02344993 chr17:57696989 CLTC 0.7 11.89 0.54 1.66e-27 Hemoglobin concentration; LIHC cis rs2857078 0.745 rs4793085 chr17:42320732 A/C cg13607699 chr17:42295918 UBTF -0.64 -11.04 -0.51 1.95e-24 Red cell distribution width;Reticulocyte count; LIHC cis rs225245 0.791 rs8067294 chr17:34027964 T/C cg05299278 chr17:33885742 SLFN14 0.23 6.2 0.32 1.65e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg13395646 chr4:1353034 KIAA1530 -0.41 -5.87 -0.3 1.01e-8 Longevity; LIHC cis rs611744 0.647 rs2597658 chr8:109256014 C/T cg18478394 chr8:109455254 TTC35 0.41 7.08 0.36 8.06e-12 Dupuytren's disease; LIHC cis rs9640161 0.673 rs11773351 chr7:150030963 T/C cg27494647 chr7:150038898 RARRES2 0.34 6.18 0.32 1.81e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs4073582 0.595 rs1115508 chr11:65923149 A/G cg14036092 chr11:66035641 RAB1B 0.4 5.94 0.31 7.11e-9 Gout; LIHC cis rs929354 0.772 rs10230895 chr7:157007038 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.54e-28 Body mass index; LIHC cis rs9640161 0.830 rs36069544 chr7:150061538 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.48 -8.37 -0.41 1.45e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs782590 0.738 rs4312532 chr2:55812061 A/G cg03859395 chr2:55845619 SMEK2 -0.57 -9.83 -0.47 3.08e-20 Metabolic syndrome; LIHC cis rs7487075 0.578 rs4768713 chr12:46814047 A/G cg23829395 chr12:46796953 NA 0.35 6.26 0.32 1.16e-9 Itch intensity from mosquito bite; LIHC cis rs1865760 1.000 rs9348698 chr6:25929689 T/A cg17691542 chr6:26056736 HIST1H1C 0.41 6.18 0.32 1.87e-9 Height; LIHC cis rs116095464 0.558 rs10043002 chr5:226753 G/A cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs138880 0.580 rs28562884 chr22:50312869 T/C cg02269571 chr22:50332266 NA -1.03 -10.46 -0.49 2.19e-22 Schizophrenia; LIHC cis rs7909074 0.966 rs4268464 chr10:45401081 T/A cg05187965 chr10:45406764 TMEM72 -0.26 -6.44 -0.33 4.03e-10 Mean corpuscular volume; LIHC cis rs881375 0.692 rs2072438 chr9:123651301 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 6.5 0.33 2.84e-10 Rheumatoid arthritis; LIHC cis rs60871478 1.000 rs62432250 chr7:801792 C/G cg27478167 chr7:817139 HEATR2 -0.41 -5.84 -0.3 1.25e-8 Cerebrospinal P-tau181p levels; LIHC cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg20295408 chr7:1910781 MAD1L1 -0.52 -7.53 -0.38 4.48e-13 Bipolar disorder and schizophrenia; LIHC cis rs17106184 1.000 rs12072155 chr1:50908741 T/A cg07174182 chr1:51127561 FAF1 -0.54 -6.12 -0.31 2.55e-9 Type 2 diabetes; LIHC cis rs11105298 0.891 rs10858894 chr12:89914261 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.64 -7.33 -0.37 1.63e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC trans rs11146838 1 rs11146838 chr10:39149977 A/T cg18107078 chr1:162760321 HSD17B7 -0.42 -6.32 -0.32 8.18e-10 Breast cancer; LIHC cis rs2295359 0.892 rs12029362 chr1:67624231 G/A cg12940439 chr1:67600707 NA 0.4 7.01 0.35 1.29e-11 Psoriasis; LIHC cis rs7617773 0.817 rs11710861 chr3:48297560 C/T cg11946769 chr3:48343235 NME6 0.86 11.08 0.51 1.43e-24 Coronary artery disease; LIHC trans rs2439831 0.850 rs12702 chr15:44093927 C/T cg07796018 chr2:55920613 PNPT1 -0.49 -6.23 -0.32 1.34e-9 Lung cancer in ever smokers; LIHC cis rs4808199 0.947 rs7250658 chr19:19571100 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.43 6.11 0.31 2.75e-9 Nonalcoholic fatty liver disease; LIHC trans rs208520 1.000 rs12192261 chr6:66985268 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 7.07 0.36 8.67e-12 Exhaled nitric oxide output; LIHC cis rs12478296 0.786 rs55876934 chr2:243033816 C/T cg06360820 chr2:242988706 NA -0.83 -11.69 -0.53 8.34e-27 Obesity-related traits; LIHC cis rs896854 0.654 rs896846 chr8:95972453 G/A cg09323728 chr8:95962352 TP53INP1 -0.28 -6.06 -0.31 3.54e-9 Type 2 diabetes; LIHC cis rs919433 0.680 rs3792160 chr2:198403519 G/A cg03934865 chr2:198174659 NA 0.52 7.88 0.39 4.42e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11671005 0.735 rs11668420 chr19:58937836 G/A cg25952890 chr19:58913133 NA 0.69 7.48 0.37 6.31e-13 Mean platelet volume; LIHC cis rs8014671 0.512 rs11624424 chr14:70980424 A/G cg25576086 chr14:70833871 SYNJ2BP -0.43 -6.49 -0.33 2.97e-10 Prostate cancer; LIHC cis rs17854409 0.764 rs3761301 chr20:61494021 C/T cg07645718 chr20:61493192 TCFL5 0.81 6.08 0.31 3.21e-9 Obesity-related traits; LIHC cis rs3749237 0.595 rs4955412 chr3:49418168 A/C cg03060546 chr3:49711283 APEH 0.58 9.54 0.46 2.7e-19 Resting heart rate; LIHC cis rs9596863 0.948 rs9568907 chr13:54335565 C/G ch.13.53330881F chr13:54432880 NA 0.45 6.22 0.32 1.45e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1059312 0.932 rs4760589 chr12:129284382 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -14.46 -0.62 2.58e-37 Systemic lupus erythematosus; LIHC cis rs6456156 0.586 rs13195158 chr6:167481392 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.56 -0.42 3.8e-16 Primary biliary cholangitis; LIHC cis rs758324 0.947 rs7708140 chr5:131252396 A/G cg06307176 chr5:131281290 NA 0.42 6.24 0.32 1.27e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs748404 0.587 rs9920879 chr15:43639770 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.55 9.73 0.47 6.35e-20 Lung cancer; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg06366937 chr1:74663927 TNNI3K;FPGT;LRRIQ3 -0.4 -6.33 -0.32 7.67e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs74233809 1.000 rs78260931 chr10:104721962 G/C cg03493300 chr10:104813866 CNNM2 0.46 6.0 0.31 4.96e-9 Birth weight; LIHC trans rs61931739 0.534 rs10844732 chr12:34037104 A/C cg26384229 chr12:38710491 ALG10B 0.5 7.0 0.35 1.36e-11 Morning vs. evening chronotype; LIHC cis rs3806843 0.735 rs801189 chr5:140063091 A/G cg19875535 chr5:140030758 IK -0.41 -6.63 -0.34 1.32e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7917772 0.582 rs4917978 chr10:104366353 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.51 -7.96 -0.4 2.56e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1005277 0.579 rs9299760 chr10:38377920 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7918232 0.800 rs7907981 chr10:27444329 T/C cg14240646 chr10:27532245 ACBD5 -0.62 -6.44 -0.33 4.1e-10 Breast cancer; LIHC cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg21724239 chr8:58056113 NA 0.48 6.36 0.33 6.46e-10 Developmental language disorder (linguistic errors); LIHC cis rs1023500 0.505 rs134878 chr22:42663874 A/G cg15557168 chr22:42548783 NA -0.34 -6.01 -0.31 4.77e-9 Schizophrenia; LIHC cis rs12249377 0.519 rs12259060 chr10:92579949 A/G cg14313238 chr10:92632228 RPP30 0.38 6.28 0.32 1.01e-9 White matter microstructure (global fractional anisotropy); LIHC cis rs12477438 0.798 rs1993230 chr2:99686079 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.91 -0.54 1.38e-27 Chronic sinus infection; LIHC cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.43 0.45 6.52e-19 Bipolar disorder; LIHC trans rs1814175 0.559 rs1818892 chr11:49863084 C/A cg03929089 chr4:120376271 NA -0.83 -15.93 -0.65 4.11e-43 Height; LIHC cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg10360323 chr17:41437877 NA 0.4 5.97 0.31 6.08e-9 Menopause (age at onset); LIHC cis rs7091068 0.616 rs6583905 chr10:95504022 T/G cg20715218 chr10:95462985 C10orf4 0.57 5.86 0.3 1.07e-8 Urinary tract infection frequency; LIHC cis rs9549367 0.756 rs2316463 chr13:113901406 C/T cg18105134 chr13:113819100 PROZ -0.68 -11.46 -0.53 5.72e-26 Platelet distribution width; LIHC cis rs7635838 0.859 rs6786166 chr3:11511424 T/C cg00170343 chr3:11313890 ATG7 0.39 6.06 0.31 3.61e-9 HDL cholesterol; LIHC cis rs10744422 0.858 rs7980541 chr12:123379477 C/T cg25930673 chr12:123319894 HIP1R -0.89 -11.68 -0.53 9.6800000000000007e-27 Schizophrenia; LIHC cis rs3741151 1.000 rs75004180 chr11:73024739 A/G cg17517138 chr11:73019481 ARHGEF17 0.93 6.84 0.35 3.7e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09280946 chr11:88070661 CTSC -0.41 -6.06 -0.31 3.68e-9 Pancreatic cancer; LIHC cis rs8114671 0.805 rs4616 chr20:33590358 C/T cg07148914 chr20:33460835 GGT7 -0.56 -8.6 -0.42 3.01e-16 Height; LIHC cis rs7772486 0.701 rs7772717 chr6:145954854 T/C cg23711669 chr6:146136114 FBXO30 0.73 13.31 0.58 7.61e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg13409248 chr3:40428643 ENTPD3 0.48 7.91 0.39 3.54e-14 Renal cell carcinoma; LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg07677032 chr17:61819896 STRADA 0.42 6.23 0.32 1.36e-9 Prudent dietary pattern; LIHC trans rs7618501 0.966 rs2352974 chr3:49890613 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.77 13.7 0.6 2.33e-34 Intelligence (multi-trait analysis); LIHC cis rs7918232 0.882 rs6415983 chr10:27357211 A/G cg14240646 chr10:27532245 ACBD5 -0.62 -5.87 -0.3 1.02e-8 Breast cancer; LIHC cis rs2637266 0.935 rs2579751 chr10:78339890 G/A cg18941641 chr10:78392320 NA 0.29 6.19 0.32 1.74e-9 Pulmonary function; LIHC cis rs4908768 0.539 rs6675443 chr1:8651582 T/A cg20416874 chr1:8611966 RERE -0.66 -12.38 -0.56 2.52e-29 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs9475752 0.744 rs6459174 chr6:56786055 C/T cg25726699 chr6:135826776 C6orf217 0.4 6.09 0.31 2.97e-9 Menarche (age at onset); LIHC cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2645694 0.626 rs2703140 chr4:77830057 C/G cg03477792 chr4:77819574 ANKRD56 0.57 7.57 0.38 3.58e-13 Emphysema distribution in smoking; LIHC cis rs9858542 0.953 rs11711485 chr3:49491983 G/T cg02487422 chr3:49467188 NICN1 -0.42 -5.86 -0.3 1.11e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2075371 0.897 rs1646733 chr7:134002228 C/A cg20476274 chr7:133979776 SLC35B4 0.7 11.47 0.53 5.47e-26 Mean platelet volume; LIHC trans rs2797160 1.000 rs2797160 chr6:126010116 A/G cg05039488 chr6:79577232 IRAK1BP1 0.46 6.52 0.33 2.57e-10 Endometrial cancer; LIHC cis rs7577696 0.597 rs17011801 chr2:32298072 A/T cg02381751 chr2:32503542 YIPF4 -0.44 -6.12 -0.31 2.59e-9 Inflammatory biomarkers; LIHC cis rs2439831 0.850 rs10163054 chr15:44047638 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.4 0.33 5.2e-10 Lung cancer in ever smokers; LIHC trans rs79976124 0.797 rs2226266 chr6:66617302 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.61 6.07 0.31 3.47e-9 Type 2 diabetes; LIHC cis rs10876993 0.890 rs1585781 chr12:58056701 T/G cg18357645 chr12:58087776 OS9 0.51 8.35 0.41 1.72e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs7552404 0.731 rs10873808 chr1:76406767 T/C cg10523679 chr1:76189770 ACADM 0.61 7.09 0.36 7.83e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2228479 0.850 rs17227263 chr16:89810598 G/A cg04013166 chr16:89971882 TCF25 0.49 6.08 0.31 3.24e-9 Skin colour saturation; LIHC cis rs11190604 1.000 rs2295774 chr10:102265847 A/C cg07080220 chr10:102295463 HIF1AN 0.57 8.18 0.4 5.52e-15 Palmitoleic acid (16:1n-7) levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg27196102 chr16:23464713 COG7 -0.4 -6.46 -0.33 3.62e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs7589728 0.516 rs79815126 chr2:88488270 G/A cg07952391 chr2:88470173 THNSL2 0.82 7.29 0.37 2.18e-12 Plasma clusterin levels; LIHC cis rs9517313 0.770 rs9517301 chr13:99095088 A/G cg22223119 chr13:99095684 FARP1 -0.39 -5.89 -0.3 9.05e-9 Neuroticism; LIHC cis rs1062177 1.000 rs12654573 chr5:151207473 T/G cg00977110 chr5:151150581 G3BP1 0.51 6.47 0.33 3.3e-10 Preschool internalizing problems; LIHC cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg26818010 chr10:134567672 INPP5A -0.79 -9.58 -0.46 2e-19 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10078 0.571 rs890973 chr5:471494 T/C cg07599136 chr5:415885 AHRR 0.78 12.78 0.57 7.81e-31 Fat distribution (HIV); LIHC cis rs6089829 1.000 rs6089828 chr20:61668998 C/T cg08564027 chr20:61660810 NA 0.39 7.27 0.37 2.41e-12 Prostate cancer (SNP x SNP interaction); LIHC cis rs2115630 1.000 rs11073730 chr15:85354596 C/T cg12501888 chr15:85177176 SCAND2 -0.47 -7.29 -0.37 2.22e-12 P wave terminal force; LIHC cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg23205692 chr1:25664452 TMEM50A -0.38 -6.17 -0.32 1.92e-9 Erythrocyte sedimentation rate; LIHC cis rs3096299 0.935 rs3102387 chr16:89432276 A/C cg08822215 chr16:89438651 ANKRD11 -0.46 -7.18 -0.36 4.43e-12 Multiple myeloma (IgH translocation); LIHC cis rs7131987 0.621 rs11050181 chr12:29467669 C/T cg16970926 chr12:29381810 FAR2 0.28 5.93 0.31 7.5e-9 QT interval; LIHC cis rs7769051 1.000 rs6910639 chr6:133120553 A/G cg07930552 chr6:133119739 C6orf192 0.67 6.38 0.33 5.77e-10 Type 2 diabetes nephropathy; LIHC cis rs1059312 0.932 rs4760593 chr12:129287220 A/G cg09035930 chr12:129282057 SLC15A4 0.68 12.98 0.57 1.29e-31 Systemic lupus erythematosus; LIHC cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg14393609 chr7:65229607 NA 0.45 6.59 0.34 1.69e-10 Aortic root size; LIHC cis rs10484885 0.824 rs72921954 chr6:90586656 A/G cg13799429 chr6:90582589 CASP8AP2 -0.69 -6.54 -0.33 2.29e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs77861329 1.000 rs9857878 chr3:52109668 A/G cg08692210 chr3:52188851 WDR51A -0.79 -7.27 -0.37 2.47e-12 Macrophage inflammatory protein 1b levels; LIHC cis rs765787 0.530 rs11636440 chr15:45535982 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs34779708 0.931 rs11010101 chr10:35411045 T/A cg04310649 chr10:35416472 CREM -0.45 -6.08 -0.31 3.17e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4925386 1.000 rs4925386 chr20:60921044 C/T cg03945807 chr20:60948434 NA 0.33 6.01 0.31 4.73e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC trans rs10838798 0.504 rs11039673 chr11:48335156 G/A cg15704280 chr7:45808275 SEPT13 -0.43 -6.41 -0.33 4.8e-10 Height; LIHC cis rs16944613 0.528 rs6416554 chr15:91138290 T/C cg26821196 chr15:91095069 CRTC3 0.43 7.2 0.36 3.91e-12 Colorectal cancer; LIHC cis rs9768139 0.903 rs10262701 chr7:158114591 G/A cg25566285 chr7:158114605 PTPRN2 -0.26 -7.81 -0.39 7.2e-14 Calcium levels; LIHC cis rs700651 0.685 rs976180 chr2:198880443 C/T cg10820045 chr2:198174542 NA -0.48 -7.23 -0.36 3.1e-12 Intracranial aneurysm; LIHC cis rs801193 1.000 rs10252765 chr7:66228732 C/G cg11764359 chr7:65958608 NA 0.67 9.86 0.47 2.41e-20 Aortic root size; LIHC cis rs7487075 0.780 rs2279559 chr12:46767175 A/C cg22049899 chr12:47219821 SLC38A4 0.36 6.15 0.32 2.16e-9 Itch intensity from mosquito bite; LIHC cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg27286337 chr10:134555280 INPP5A 0.96 13.64 0.59 4.12e-34 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6815814 0.950 rs67206233 chr4:38807853 T/C cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC cis rs35306767 0.903 rs11253494 chr10:937047 C/T cg20503657 chr10:835505 NA 1.01 11.89 0.54 1.62e-27 Eosinophil percentage of granulocytes; LIHC cis rs11077998 0.935 rs12185276 chr17:80498997 T/C cg10255544 chr17:80519551 FOXK2 0.48 8.81 0.43 6.4e-17 Reticulocyte fraction of red cells; LIHC trans rs783540 0.934 rs8043401 chr15:83356259 A/G cg18393722 chr15:85113863 UBE2QP1 0.38 6.69 0.34 9.17e-11 Schizophrenia; LIHC cis rs7116495 1.000 rs6592450 chr11:71671166 C/T cg26138937 chr11:71823887 C11orf51 -0.71 -7.23 -0.36 3.14e-12 Severe influenza A (H1N1) infection; LIHC cis rs11229555 0.574 rs12271501 chr11:58214969 T/C cg15696309 chr11:58395628 NA -0.65 -7.63 -0.38 2.37e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1707322 1.000 rs1768800 chr1:46549188 A/G cg03146154 chr1:46216737 IPP -0.45 -7.27 -0.37 2.52e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.717 rs10890345 chr1:46213927 C/T cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg00343986 chr7:65444356 GUSB -0.44 -6.21 -0.32 1.54e-9 Aortic root size; LIHC cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg07061783 chr6:25882402 NA -0.47 -6.53 -0.33 2.38e-10 Blood metabolite levels; LIHC cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg25894440 chr7:65020034 NA 0.5 5.94 0.31 7.04e-9 Diabetic kidney disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03571225 chr17:54991993 TRIM25 0.41 6.14 0.32 2.34e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs12188164 0.543 rs2434695 chr5:464177 C/G cg00049323 chr5:472564 LOC25845 0.35 5.84 0.3 1.23e-8 Cystic fibrosis severity; LIHC trans rs2243480 1.000 rs313824 chr7:65581207 C/T cg10756647 chr7:56101905 PSPH 1.07 13.4 0.59 3.25e-33 Diabetic kidney disease; LIHC cis rs8180040 0.903 rs2276853 chr3:47282303 G/A cg16586182 chr3:47516702 SCAP -0.54 -9.75 -0.47 5.8e-20 Colorectal cancer; LIHC trans rs4942242 0.512 rs9533552 chr13:44187194 C/T cg19169023 chr15:41853346 TYRO3 -0.54 -7.77 -0.39 9.09e-14 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg27286337 chr10:134555280 INPP5A 0.94 13.42 0.59 2.78e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg18404041 chr3:52824283 ITIH1 -0.56 -9.01 -0.44 1.43e-17 Bipolar disorder; LIHC cis rs9916302 0.784 rs4795382 chr17:37700860 A/G cg00129232 chr17:37814104 STARD3 -0.42 -6.68 -0.34 9.86e-11 Glomerular filtration rate (creatinine); LIHC cis rs2404602 0.735 rs1607017 chr15:76726465 G/T cg23625390 chr15:77176239 SCAPER -0.48 -8.04 -0.4 1.52e-14 Blood metabolite levels; LIHC cis rs7091068 0.518 rs1543580 chr10:95446811 C/T cg20715218 chr10:95462985 C10orf4 0.58 8.32 0.41 2.15e-15 Urinary tract infection frequency; LIHC cis rs11122272 0.735 rs2749708 chr1:231529610 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC trans rs1814175 0.754 rs10219245 chr11:49645052 C/T cg03929089 chr4:120376271 NA -0.89 -17.85 -0.69 8.1e-51 Height; LIHC cis rs710865 0.541 rs2273046 chr1:19566296 C/T cg13387374 chr1:19411106 UBR4 -0.39 -5.91 -0.3 8.23e-9 Brain structure; LIHC trans rs1499614 0.803 rs1922723 chr7:66175063 C/T cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs11030122 0.569 rs11030781 chr11:4083258 T/C cg18678763 chr11:4115507 RRM1 -0.58 -8.71 -0.43 1.29e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs6964587 1.000 rs733957 chr7:91707197 C/T cg17063962 chr7:91808500 NA 1.02 19.58 0.73 8.67e-58 Breast cancer; LIHC cis rs2839186 0.967 rs4819222 chr21:47707778 G/A cg09417038 chr21:47716443 C21orf57 -0.54 -8.01 -0.4 1.8e-14 Testicular germ cell tumor; LIHC cis rs6840360 1.000 rs4696111 chr4:152671405 T/C cg22705602 chr4:152727874 NA -0.34 -7.21 -0.36 3.71e-12 Intelligence (multi-trait analysis); LIHC cis rs12458462 0.787 rs56006341 chr18:77439844 G/T cg11879182 chr18:77439856 CTDP1 0.86 14.88 0.63 5.89e-39 Monocyte count; LIHC cis rs9811920 0.609 rs4479633 chr3:99654510 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 6.89 0.35 2.64e-11 Axial length; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24413235 chr2:27851648 CCDC121;GPN1 0.43 6.22 0.32 1.42e-9 Lung function (FEV1/FVC); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07071157 chr11:72525331 ATG16L2 0.47 6.67 0.34 1e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11673344 0.932 rs76350084 chr19:37678819 A/C cg27390819 chr19:37464633 NA -0.5 -5.98 -0.31 5.53e-9 Obesity-related traits; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.86 0.39 5.2e-14 Prudent dietary pattern; LIHC trans rs1992950 0.819 rs7596078 chr2:200179843 C/T cg23743778 chr4:140357491 NA 0.36 6.06 0.31 3.67e-9 Ulcerative colitis; LIHC cis rs4268898 0.686 rs2042468 chr2:24398446 A/T cg06627628 chr2:24431161 ITSN2 0.45 6.31 0.32 8.86e-10 Asthma; LIHC cis rs11690935 0.959 rs10167419 chr2:172649826 A/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.84 -0.69 8.83e-51 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19691163 chr5:96304288 LNPEP -0.46 -6.05 -0.31 3.75e-9 Pancreatic cancer; LIHC cis rs7577696 0.597 rs7556942 chr2:32295694 G/A cg02381751 chr2:32503542 YIPF4 -0.44 -6.12 -0.31 2.59e-9 Inflammatory biomarkers; LIHC cis rs2274273 1.000 rs6573006 chr14:55610432 T/C cg04306507 chr14:55594613 LGALS3 0.33 6.18 0.32 1.83e-9 Protein biomarker; LIHC cis rs919433 0.817 rs10931780 chr2:198175297 G/C cg03934865 chr2:198174659 NA -0.59 -9.35 -0.45 1.22e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs651907 0.535 rs13065944 chr3:101473088 G/A cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.74 -0.3 2.04e-8 Colorectal cancer; LIHC cis rs67478160 0.654 rs1535097 chr14:104216649 C/T cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.95 -0.39 2.76e-14 Schizophrenia; LIHC cis rs2204008 0.744 rs66474616 chr12:38461564 G/A cg26384229 chr12:38710491 ALG10B 0.87 11.03 0.51 2.02e-24 Bladder cancer; LIHC cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg06238570 chr21:40685208 BRWD1 -0.51 -8.32 -0.41 2.14e-15 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23260255 chr3:187871479 LPP 0.41 6.48 0.33 3.26e-10 Cognitive function; LIHC cis rs12079745 0.793 rs57776592 chr1:169268023 A/G cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -7.11 -0.36 6.7e-12 QT interval; LIHC cis rs12908161 0.959 rs1051168 chr15:85200520 G/T cg12863693 chr15:85201151 NMB 0.49 6.96 0.35 1.73e-11 Schizophrenia; LIHC cis rs79149102 0.579 rs7173218 chr15:75315328 A/G cg09165964 chr15:75287851 SCAMP5 -0.58 -7.73 -0.39 1.22e-13 Lung cancer; LIHC cis rs7116495 0.609 rs567851 chr11:71592419 G/C cg10381502 chr11:71823885 C11orf51 0.83 7.24 0.36 2.93e-12 Severe influenza A (H1N1) infection; LIHC cis rs548181 0.536 rs503287 chr11:125461788 C/T cg03464685 chr11:125439445 EI24 1.0 10.43 0.49 2.75e-22 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs11039798 0.507 rs56994343 chr11:48896970 G/A cg15704280 chr7:45808275 SEPT13 0.6 6.74 0.34 6.59e-11 Axial length; LIHC cis rs9910055 0.502 rs1684662 chr17:42180822 T/A cg19774624 chr17:42201019 HDAC5 0.49 6.13 0.31 2.45e-9 Total body bone mineral density; LIHC cis rs6952808 0.630 rs1860832 chr7:2161849 G/A cg04267008 chr7:1944627 MAD1L1 -0.52 -8.19 -0.4 5.37e-15 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.825 rs801202 chr7:66023929 C/T cg18252515 chr7:66147081 NA 0.45 6.59 0.34 1.62e-10 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21575187 chr5:177558253 RMND5B 0.43 6.28 0.32 1.03e-9 Lung function (FEV1/FVC); LIHC cis rs9611565 0.592 rs56021266 chr22:41756571 C/T cg06481639 chr22:41940642 POLR3H -0.73 -6.65 -0.34 1.13e-10 Vitiligo; LIHC cis rs11711311 0.824 rs9876528 chr3:113357196 G/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.35 6.06 0.31 3.52e-9 IgG glycosylation; LIHC cis rs7944735 0.508 rs7931089 chr11:47633506 G/A cg20307385 chr11:47447363 PSMC3 -0.54 -6.07 -0.31 3.4e-9 Intraocular pressure; LIHC cis rs651907 0.557 rs11710533 chr3:101351472 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.42 -5.72 -0.3 2.32e-8 Colorectal cancer; LIHC cis rs4407350 0.967 rs5765741 chr22:44924292 A/G cg26276947 chr22:44892394 LDOC1L 0.32 5.94 0.31 7.05e-9 Intelligence (multi-trait analysis); LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg22903471 chr2:27725779 GCKR -0.5 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs7258465 1.000 rs4808134 chr19:18608579 G/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.5 -0.38 5.38e-13 Breast cancer; LIHC cis rs7727544 0.735 rs4705933 chr5:131678412 G/A cg07395648 chr5:131743802 NA -0.3 -6.22 -0.32 1.44e-9 Blood metabolite levels; LIHC cis rs1552244 0.816 rs13076197 chr3:10019773 T/C cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs17384381 0.834 rs12130380 chr1:85901309 T/C cg16011679 chr1:85725395 C1orf52 0.58 6.99 0.35 1.47e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs9457247 1.000 rs409356 chr6:167405226 T/A cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.5e-20 Crohn's disease; LIHC cis rs589448 0.934 rs554591 chr12:69753847 T/C cg20891283 chr12:69753455 YEATS4 0.95 22.44 0.77 3.39e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs2576037 0.623 rs2576042 chr18:44577461 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.62 -9.07 -0.44 9.26e-18 Personality dimensions; LIHC cis rs116979167 0.575 rs818470 chr7:105165350 A/C cg19920283 chr7:105172520 RINT1 0.48 5.95 0.31 6.52e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6701037 0.681 rs1057246 chr1:175127534 C/G cg17845761 chr1:175162550 KIAA0040 0.38 6.65 0.34 1.13e-10 Alcohol dependence; LIHC trans rs2727020 0.563 rs10769582 chr11:49474040 T/C cg03929089 chr4:120376271 NA -0.87 -17.16 -0.68 4.93e-48 Coronary artery disease; LIHC cis rs7772486 0.817 rs9386145 chr6:146363519 A/T cg05347473 chr6:146136440 FBXO30 0.35 5.84 0.3 1.21e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs10489202 0.583 rs203782 chr1:167882386 A/G cg25738037 chr1:168025549 DCAF6 0.38 5.8 0.3 1.48e-8 Schizophrenia; LIHC cis rs12586317 0.547 rs13379372 chr14:35483882 A/C cg05294307 chr14:35346193 BAZ1A -0.49 -7.42 -0.37 9.63e-13 Psoriasis; LIHC cis rs7589728 0.563 rs2292868 chr2:88475047 A/G cg14558114 chr2:88469736 THNSL2 -0.63 -6.22 -0.32 1.43e-9 Plasma clusterin levels; LIHC trans rs1814175 0.645 rs10128731 chr11:50023554 G/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs712039 0.652 rs1102920 chr17:35760940 A/G cg16670864 chr17:35848621 DUSP14 0.34 5.83 0.3 1.29e-8 Tuberculosis; LIHC cis rs7635838 0.819 rs4684782 chr3:11518755 C/T cg00170343 chr3:11313890 ATG7 -0.4 -6.3 -0.32 9.31e-10 HDL cholesterol; LIHC cis rs2204008 0.641 rs66876045 chr12:38205713 G/A cg26384229 chr12:38710491 ALG10B 0.82 10.25 0.48 1.14e-21 Bladder cancer; LIHC cis rs3741404 0.609 rs669913 chr11:63869879 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.67 10.83 0.51 1.06e-23 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03759077 chr2:153575599 ARL6IP6 0.45 6.58 0.34 1.74e-10 Pancreatic cancer; LIHC cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg00091569 chr3:40428383 ENTPD3 -0.39 -6.56 -0.33 1.97e-10 Renal cell carcinoma; LIHC cis rs7208859 0.673 rs73265624 chr17:29232066 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2439831 0.850 rs28509275 chr15:44098105 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.61 7.93 0.39 3.17e-14 Lung cancer in ever smokers; LIHC trans rs12752401 1.000 rs35190459 chr1:103089554 T/A cg17681729 chr19:740608 PALM 0.49 6.42 0.33 4.46e-10 Resistance to antihypertensive treatment in hypertension; LIHC cis rs7224737 1.000 rs9889618 chr17:40293467 C/T cg00647820 chr17:40259828 DHX58 -0.28 -5.91 -0.3 8.35e-9 Fibrinogen levels; LIHC cis rs9479482 0.935 rs5017315 chr6:150333574 C/T cg25797454 chr6:150327115 RAET1K 0.34 6.15 0.32 2.16e-9 Alopecia areata; LIHC cis rs4930103 0.935 rs2075745 chr11:2018336 A/T cg06197492 chr11:2016605 H19 0.38 6.08 0.31 3.28e-9 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg11890956 chr21:40555474 PSMG1 -0.5 -8.07 -0.4 1.19e-14 Cognitive function; LIHC cis rs11690935 0.959 rs7562356 chr2:172626611 C/G cg13550731 chr2:172543902 DYNC1I2 -0.94 -18.95 -0.72 3.02e-55 Schizophrenia; LIHC cis rs5769765 0.955 rs9616394 chr22:50314927 G/C cg02269571 chr22:50332266 NA -0.75 -9.94 -0.47 1.29e-20 Schizophrenia; LIHC cis rs4555082 0.834 rs2816623 chr14:105733295 G/A cg13114125 chr14:105738426 BRF1 -0.79 -10.09 -0.48 4e-21 Mean platelet volume;Platelet distribution width; LIHC trans rs7615952 0.575 rs35949599 chr3:125544202 G/A cg07211511 chr3:129823064 LOC729375 -0.49 -7.59 -0.38 3.02e-13 Blood pressure (smoking interaction); LIHC cis rs4803468 1.000 rs284654 chr19:41928724 G/A cg09537434 chr19:41945824 ATP5SL -1.03 -21.26 -0.75 1.63e-64 Height; LIHC cis rs6952808 0.760 rs11764960 chr7:1950532 G/A cg21782813 chr7:2030301 MAD1L1 0.48 8.12 0.4 8.4e-15 Bipolar disorder and schizophrenia; LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg26354017 chr1:205819088 PM20D1 0.74 11.12 0.52 9.68e-25 Menarche (age at onset); LIHC cis rs1005277 0.579 rs2505197 chr10:38393310 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs1005277 0.589 rs2749624 chr10:38529865 A/G cg00409905 chr10:38381863 ZNF37A -0.56 -9.38 -0.45 9.31e-19 Extrinsic epigenetic age acceleration; LIHC cis rs743757 0.878 rs1467914 chr3:50523668 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.4 5.92 0.31 7.63e-9 Diastolic blood pressure; LIHC cis rs6089584 0.830 rs4925331 chr20:60580174 T/C cg06108461 chr20:60628389 TAF4 -0.89 -13.83 -0.6 7.09e-35 Body mass index; LIHC cis rs8027181 0.839 rs62017600 chr15:73072236 T/A cg25632853 chr15:73088954 NA 0.38 6.31 0.32 8.46e-10 Triglyceride levels; LIHC cis rs1577917 1.000 rs2816821 chr6:86657084 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.71 -0.38 1.4e-13 Response to antipsychotic treatment; LIHC cis rs7412746 0.658 rs10888397 chr1:150886752 A/G cg18016565 chr1:150552671 MCL1 -0.5 -9.95 -0.47 1.17e-20 Melanoma; LIHC cis rs6570726 0.846 rs397311 chr6:145806701 C/T cg23711669 chr6:146136114 FBXO30 -0.54 -9.93 -0.47 1.41e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs116095464 0.510 rs7723883 chr5:270798 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.32 0.45 1.5e-18 Bipolar disorder; LIHC cis rs8072100 0.934 rs6504872 chr17:45438952 C/T cg08085267 chr17:45401833 C17orf57 -0.61 -9.23 -0.45 2.99e-18 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg20607798 chr8:58055168 NA 0.68 8.43 0.41 9.8e-16 Developmental language disorder (linguistic errors); LIHC cis rs7399018 0.643 rs6580810 chr12:51610478 C/T cg12163867 chr12:51592794 POU6F1 -0.37 -6.32 -0.32 7.98e-10 Cisplatin-induced ototoxicity; LIHC cis rs904251 0.600 rs1874736 chr6:37447994 C/G cg01843034 chr6:37503916 NA -0.38 -6.28 -0.32 1.06e-9 Cognitive performance; LIHC cis rs798554 0.959 rs798556 chr7:2759002 C/A cg19346786 chr7:2764209 NA -0.41 -6.09 -0.31 3e-9 Height; LIHC cis rs2839186 0.605 rs2839174 chr21:47676934 T/C cg12516959 chr21:47718080 NA -0.4 -6.41 -0.33 4.72e-10 Testicular germ cell tumor; LIHC cis rs9457247 0.935 rs2757046 chr6:167374353 C/T cg12798992 chr6:167411361 FGFR1OP -0.6 -9.93 -0.47 1.41e-20 Crohn's disease; LIHC cis rs240764 0.853 rs12206945 chr6:101018032 C/T cg09795085 chr6:101329169 ASCC3 0.43 5.76 0.3 1.88e-8 Neuroticism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02797930 chr3:153839287 SGEF 0.42 6.22 0.32 1.42e-9 Lung function (FEV1/FVC); LIHC cis rs11958404 1.000 rs72816532 chr5:157413130 C/T cg05962755 chr5:157440814 NA 0.86 10.11 0.48 3.51e-21 IgG glycosylation; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01374398 chr3:47516975 SCAP 0.46 6.12 0.31 2.56e-9 Lung function (FEV1/FVC); LIHC cis rs589448 0.902 rs315131 chr12:69761839 T/G cg19645103 chr12:69753606 YEATS4 -0.39 -5.87 -0.3 1.06e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs10464366 0.510 rs62442212 chr7:39146896 A/C cg20302533 chr7:39170763 POU6F2 0.34 6.25 0.32 1.2e-9 IgG glycosylation; LIHC cis rs4969178 0.560 rs4969182 chr17:76393030 T/C cg20026190 chr17:76395443 PGS1 0.41 6.04 0.31 4.05e-9 HDL cholesterol levels; LIHC cis rs801193 0.636 rs10233806 chr7:66118248 G/C cg11764359 chr7:65958608 NA -0.83 -14.63 -0.62 5.6e-38 Aortic root size; LIHC cis rs6503525 0.591 rs8080734 chr17:38103285 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.37 -5.93 -0.31 7.5e-9 Asthma; LIHC cis rs2404602 0.662 rs908817 chr15:76639191 G/A cg03037974 chr15:76606532 NA -0.65 -11.49 -0.53 4.62e-26 Blood metabolite levels; LIHC cis rs7903847 0.642 rs9887991 chr10:99159634 T/C cg08345082 chr10:99160200 RRP12 -0.39 -6.65 -0.34 1.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9479482 1.000 rs9478354 chr6:150334366 G/A cg25797454 chr6:150327115 RAET1K 0.33 5.92 0.3 7.99e-9 Alopecia areata; LIHC cis rs559928 0.606 rs17773078 chr11:63906224 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 7.46 0.37 7.18e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC trans rs11722228 0.522 rs12504600 chr4:10067138 C/A cg26043149 chr18:55253948 FECH 0.82 9.98 0.47 9.55e-21 Gout;Urate levels;Serum uric acid levels; LIHC cis rs17685 0.633 rs3801471 chr7:75696188 T/G cg04610667 chr7:75704037 NA -0.35 -6.3 -0.32 9.18e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg15691649 chr6:25882328 NA 0.41 6.08 0.31 3.29e-9 Blood metabolite levels; LIHC cis rs2274273 0.967 rs8009670 chr14:55583477 G/A cg04306507 chr14:55594613 LGALS3 0.32 6.25 0.32 1.19e-9 Protein biomarker; LIHC cis rs2576037 0.623 rs2571000 chr18:44580347 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.6 -8.82 -0.43 5.94e-17 Personality dimensions; LIHC cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg25364880 chr3:44379878 C3orf23 0.57 7.7 0.38 1.46e-13 Depressive symptoms; LIHC cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg06481639 chr22:41940642 POLR3H -0.71 -7.08 -0.36 8.3e-12 Vitiligo; LIHC cis rs1113500 0.933 rs10494089 chr1:108626695 T/G cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.92e-12 Growth-regulated protein alpha levels; LIHC cis rs151349 1.000 rs151346 chr20:57587040 C/A cg23907860 chr20:57583709 CTSZ -0.43 -7.0 -0.35 1.38e-11 Platelet distribution width; LIHC cis rs1570884 0.516 rs2094108 chr13:50171550 G/A cg03651054 chr13:50194643 NA 0.38 6.64 0.34 1.23e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13811713 chr2:216946683 PECR;TMEM169 0.48 6.64 0.34 1.23e-10 Lung function (FEV1/FVC); LIHC cis rs6121246 0.697 rs6060446 chr20:30231637 T/C cg13852791 chr20:30311386 BCL2L1 0.83 8.41 0.41 1.14e-15 Mean corpuscular hemoglobin; LIHC cis rs9326248 0.520 rs6589602 chr11:117037065 T/C cg11861562 chr11:117069780 TAGLN 0.37 5.96 0.31 6.22e-9 Blood protein levels; LIHC cis rs11628318 0.614 rs62007936 chr14:103198740 G/A cg01864069 chr14:103024347 NA 0.47 7.14 0.36 5.76e-12 Platelet count; LIHC cis rs6684514 1.000 rs6800 chr1:156262653 A/C cg16558208 chr1:156270281 VHLL 0.54 10.1 0.48 3.59e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs4713118 0.513 rs1225591 chr6:28148752 G/A cg16479474 chr6:28041457 NA 0.39 6.53 0.33 2.39e-10 Parkinson's disease; LIHC trans rs9858542 1.000 rs13316695 chr3:49684917 C/G cg21659725 chr3:3221576 CRBN -0.57 -6.41 -0.33 4.91e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs7224685 0.569 rs12453798 chr17:4017079 C/T cg09695851 chr17:3907499 NA 0.61 6.88 0.35 2.92e-11 Type 2 diabetes; LIHC cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg07636037 chr3:49044803 WDR6 0.77 13.15 0.58 3.14e-32 Menarche (age at onset); LIHC cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg26116260 chr4:7069785 GRPEL1 1.01 18.46 0.71 2.82e-53 Monocyte percentage of white cells; LIHC cis rs16828019 0.929 rs1032728 chr1:41679566 A/T cg03962019 chr1:41807865 NA 0.5 7.26 0.37 2.68e-12 Intelligence (multi-trait analysis); LIHC cis rs6429082 0.714 rs704719 chr1:235667170 G/A cg26050004 chr1:235667680 B3GALNT2 0.48 7.42 0.37 9.46e-13 Adiposity; LIHC cis rs372883 0.648 rs1003772 chr21:30736145 A/T cg08807101 chr21:30365312 RNF160 0.54 6.29 0.32 9.86e-10 Pancreatic cancer; LIHC cis rs7100689 0.646 rs2486302 chr10:82076600 G/A cg00277334 chr10:82204260 NA -0.59 -7.46 -0.37 7.39e-13 Post bronchodilator FEV1; LIHC cis rs4268898 0.662 rs2303292 chr2:24432138 C/T cg06627628 chr2:24431161 ITSN2 -0.73 -9.61 -0.46 1.67e-19 Asthma; LIHC cis rs7772486 0.754 rs9386132 chr6:146140751 T/C cg23711669 chr6:146136114 FBXO30 0.74 13.38 0.59 3.86e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg07424592 chr7:64974309 NA -0.79 -9.28 -0.45 1.95e-18 Diabetic kidney disease; LIHC cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg08219700 chr8:58056026 NA 0.51 6.73 0.34 7.07e-11 Developmental language disorder (linguistic errors); LIHC cis rs6089829 1.000 rs62207535 chr20:61669187 A/G cg03213289 chr20:61660250 NA 0.51 8.78 0.43 7.72e-17 Prostate cancer (SNP x SNP interaction); LIHC trans rs2073499 1.000 rs78020607 chr3:50254624 A/G cg21659725 chr3:3221576 CRBN 0.58 6.38 0.33 5.81e-10 Schizophrenia; LIHC cis rs739401 0.619 rs10766481 chr11:2961512 G/C cg05729581 chr11:3078854 CARS -0.41 -5.71 -0.3 2.41e-8 Longevity; LIHC cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg06558623 chr16:89946397 TCF25 1.0 15.75 0.65 2.08e-42 Skin colour saturation; LIHC cis rs9640161 0.830 rs13307276 chr7:150061525 T/C cg21361702 chr7:150065534 REPIN1 0.55 7.7 0.38 1.53e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs2180341 0.924 rs877661 chr6:127587915 T/G cg27446573 chr6:127587934 RNF146 1.0 15.42 0.64 4.09e-41 Breast cancer; LIHC trans rs3780486 0.846 rs10971419 chr9:33124161 T/C cg04842962 chr6:43655489 MRPS18A 1.05 24.99 0.8 3.62e-79 IgG glycosylation; LIHC cis rs7528419 0.895 rs599839 chr1:109822166 A/G cg00908766 chr1:109817496 CELSR2 -0.43 -7.9 -0.39 3.78e-14 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs9916302 0.904 rs9898170 chr17:37510092 T/C cg03013999 chr17:37608204 MED1 -0.34 -5.76 -0.3 1.91e-8 Glomerular filtration rate (creatinine); LIHC cis rs801193 1.000 rs1553609 chr7:66197139 T/C cg11764359 chr7:65958608 NA 0.71 10.72 0.5 2.6e-23 Aortic root size; LIHC cis rs4148883 0.675 rs11724783 chr4:100099688 C/A cg12011299 chr4:100065546 ADH4 0.36 7.16 0.36 4.98e-12 Alcohol dependence; LIHC cis rs9814567 1.000 rs2056603 chr3:134312749 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.0 -0.31 5.1e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs17253792 0.822 rs113649689 chr14:56088065 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg11764359 chr7:65958608 NA 0.59 6.01 0.31 4.63e-9 Diabetic kidney disease; LIHC cis rs17685 0.702 rs6960598 chr7:75772991 T/C cg01364799 chr7:75623366 TMEM120A -0.41 -6.12 -0.31 2.5e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4819052 0.851 rs2838845 chr21:46670812 A/G cg11663144 chr21:46675770 NA -0.32 -5.92 -0.3 7.73e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg20891558 chr2:74357851 NA 0.8 16.41 0.66 4.89e-45 Gestational age at birth (maternal effect); LIHC trans rs10411161 0.810 rs4267442 chr19:52363727 C/A cg22319618 chr22:45562946 NUP50 -0.52 -6.48 -0.33 3.15e-10 Breast cancer; LIHC cis rs3540 0.574 rs2657946 chr15:90967513 G/C cg22089800 chr15:90895588 ZNF774 0.55 7.62 0.38 2.45e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2153535 0.580 rs5001130 chr6:8442298 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.89 0.39 4.23e-14 Motion sickness; LIHC cis rs1348850 0.567 rs7605609 chr2:178534942 C/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 8.07 0.4 1.21e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs11122272 0.735 rs910823 chr1:231498766 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.83 -0.51 1.06e-23 Hemoglobin concentration; LIHC cis rs9303280 0.868 rs11650661 chr17:38026286 A/T cg11212589 chr17:38028394 ZPBP2 0.35 7.17 0.36 4.67e-12 Self-reported allergy; LIHC trans rs12753920 0.724 rs2093879 chr1:92585831 C/G cg15668468 chr10:118892869 VAX1 -0.43 -6.26 -0.32 1.15e-9 Systemic lupus erythematosus; LIHC cis rs74233809 1.000 rs12412038 chr10:104856162 G/A cg03493300 chr10:104813866 CNNM2 0.46 6.13 0.31 2.43e-9 Birth weight; LIHC cis rs7927592 0.763 rs7129248 chr11:68263276 A/T cg01657329 chr11:68192670 LRP5 -0.5 -7.32 -0.37 1.78e-12 Total body bone mineral density; LIHC cis rs12701220 0.504 rs12702092 chr7:1145868 G/A cg00990874 chr7:1149470 C7orf50 -0.67 -8.89 -0.43 3.45e-17 Bronchopulmonary dysplasia; LIHC cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg04025307 chr7:1156635 C7orf50 0.67 11.66 0.53 1.13e-26 Longevity;Endometriosis; LIHC trans rs1814175 0.754 rs10839453 chr11:49955815 A/T cg03929089 chr4:120376271 NA -0.9 -18.35 -0.7 7.75e-53 Height; LIHC cis rs780096 0.526 rs11126999 chr2:27670307 G/A cg22903471 chr2:27725779 GCKR -0.51 -8.91 -0.43 2.99e-17 Total body bone mineral density; LIHC cis rs7772486 0.790 rs3923579 chr6:146230232 C/G cg05347473 chr6:146136440 FBXO30 -0.38 -6.05 -0.31 3.73e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg00591980 chr6:150071069 PCMT1 -0.53 -6.08 -0.31 3.12e-9 Systolic blood pressure; LIHC cis rs2832191 1.000 rs2832183 chr21:30482150 G/A cg08807101 chr21:30365312 RNF160 -0.61 -9.52 -0.46 3.36e-19 Dental caries; LIHC cis rs2274273 0.901 rs12050099 chr14:55764331 G/C cg01864836 chr14:55583639 NA -0.37 -6.46 -0.33 3.52e-10 Protein biomarker; LIHC cis rs3770081 1.000 rs3810827 chr2:86334386 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.44 6.11 0.31 2.74e-9 Facial emotion recognition (sad faces); LIHC trans rs12030196 0.788 rs10889125 chr1:59417116 A/G cg25148632 chr5:166402453 NA 0.23 6.15 0.32 2.2e-9 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs3121446 1.000 rs3127661 chr6:107141927 A/G cg26014185 chr6:10033784 NA 0.2 6.18 0.32 1.85e-9 Daytime sleep phenotypes; LIHC cis rs35306767 0.807 rs1013505 chr10:953273 C/T cg26597838 chr10:835615 NA 1.1 12.42 0.56 1.76e-29 Eosinophil percentage of granulocytes; LIHC cis rs7937682 0.883 rs510388 chr11:111451869 G/T cg09085632 chr11:111637200 PPP2R1B 0.75 9.25 0.45 2.54e-18 Primary sclerosing cholangitis; LIHC cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg12379764 chr21:47803548 PCNT -0.55 -8.18 -0.4 5.75e-15 Testicular germ cell tumor; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09273779 chr9:35605990 TESK1 0.42 7.09 0.36 7.7e-12 Cognitive function; LIHC cis rs546131 0.928 rs558967 chr11:34827168 T/A cg06937548 chr11:34938143 PDHX;APIP 0.58 7.88 0.39 4.42e-14 Lung disease severity in cystic fibrosis; LIHC cis rs2204008 0.571 rs7970136 chr12:38531951 G/C cg26384229 chr12:38710491 ALG10B -0.49 -6.79 -0.34 4.84e-11 Bladder cancer; LIHC cis rs787274 1.000 rs7868830 chr9:115577125 G/A cg13803584 chr9:115635662 SNX30 -0.61 -6.78 -0.34 5.29e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs155076 1.000 rs261427 chr13:21860998 G/A cg14456004 chr13:21872349 NA -1.09 -12.16 -0.55 1.62e-28 White matter hyperintensity burden; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13352455 chr3:53230110 NA -0.45 -6.25 -0.32 1.24e-9 Pancreatic cancer; LIHC cis rs11676348 0.808 rs61700947 chr2:219046171 C/G cg00012203 chr2:219082015 ARPC2 0.48 6.29 0.32 9.87e-10 Ulcerative colitis; LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg08219700 chr8:58056026 NA 0.52 6.95 0.35 1.85e-11 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC trans rs7618501 1.000 rs695238 chr3:49869158 A/C cg19936157 chr1:113287238 NA -0.33 -6.03 -0.31 4.15e-9 Intelligence (multi-trait analysis); LIHC cis rs4073582 0.595 rs474005 chr11:66033301 C/T cg14036092 chr11:66035641 RAB1B 0.45 6.72 0.34 7.4e-11 Gout; LIHC cis rs11764590 0.715 rs9969125 chr7:2088460 C/T cg23422044 chr7:1970798 MAD1L1 -0.5 -5.78 -0.3 1.71e-8 Neuroticism; LIHC cis rs147858478 1 rs147858478 chr5:131682785 CCTGAGTT/C cg07395648 chr5:131743802 NA -0.31 -6.39 -0.33 5.38e-10 High light scatter reticulocyte percentage of red cells; LIHC trans rs4824093 0.610 rs73441787 chr22:50269646 A/G cg09872104 chr7:134855509 C7orf49 -0.76 -6.09 -0.31 2.99e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs7520050 0.966 rs10890354 chr1:46305347 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg04013166 chr16:89971882 TCF25 0.63 8.52 0.42 5.31e-16 Skin colour saturation; LIHC cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg19774624 chr17:42201019 HDAC5 -0.8 -12.25 -0.55 7.25e-29 Total body bone mineral density; LIHC cis rs1348850 0.914 rs4893957 chr2:178380409 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.9 14.47 0.62 2.39e-37 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs295140 0.605 rs296818 chr2:201176944 C/T cg23649088 chr2:200775458 C2orf69 0.43 5.99 0.31 5.25e-9 QT interval; LIHC cis rs17125944 0.686 rs7158645 chr14:53332152 C/T cg00686598 chr14:53173677 PSMC6 -0.8 -9.17 -0.44 4.51e-18 Alzheimer's disease (late onset); LIHC cis rs6952808 0.792 rs2056481 chr7:1955435 A/G cg02951883 chr7:2050386 MAD1L1 -0.6 -8.97 -0.44 2.04e-17 Bipolar disorder and schizophrenia; LIHC cis rs7520050 0.966 rs12405451 chr1:46384326 T/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.81e-9 Red blood cell count;Reticulocyte count; LIHC cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.08 -0.31 3.3e-9 Total body bone mineral density; LIHC cis rs4474465 0.915 rs10899512 chr11:78171338 G/A cg27205649 chr11:78285834 NARS2 -0.37 -5.74 -0.3 2.14e-8 Alzheimer's disease (survival time); LIHC cis rs9503598 0.522 rs6938957 chr6:3430835 G/A cg00476032 chr6:3446245 SLC22A23 -0.32 -5.85 -0.3 1.18e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs1707322 0.928 rs61785614 chr1:46446047 A/G cg03146154 chr1:46216737 IPP 0.48 7.9 0.39 3.93e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9513627 1.000 rs73556170 chr13:100121612 T/A cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs769267 0.895 rs1858999 chr19:19497669 C/G cg03709012 chr19:19516395 GATAD2A -0.99 -17.15 -0.68 5.13e-48 Tonsillectomy; LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg11905131 chr22:24372483 LOC391322 0.68 10.16 0.48 2.25e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7191439 0.728 rs8043637 chr16:88781125 T/C cg27087555 chr16:88793112 FAM38A -1.31 -12.32 -0.55 4.22e-29 Plateletcrit; LIHC cis rs116095464 0.558 rs11959126 chr5:283880 T/G cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs2841277 0.802 rs2841269 chr14:105386149 C/G cg21017887 chr14:105400489 NA 0.62 10.99 0.51 2.84e-24 Rheumatoid arthritis; LIHC cis rs79149102 0.579 rs6495142 chr15:75320166 C/T cg16226627 chr15:75307476 SCAMP5 0.54 9.88 0.47 2.04e-20 Lung cancer; LIHC cis rs9303401 0.659 rs34468504 chr17:56648277 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs7945718 0.875 rs9888179 chr11:12782601 G/T cg25843174 chr11:12811716 TEAD1 0.34 7.76 0.39 9.8e-14 Educational attainment (years of education); LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs6740035 chr2:99576578 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.06 -0.51 1.7e-24 Chronic sinus infection; LIHC cis rs17106184 1.000 rs60290409 chr1:51404041 C/A cg07174182 chr1:51127561 FAF1 -0.74 -7.94 -0.39 2.99e-14 Type 2 diabetes; LIHC cis rs3749237 0.595 rs11130196 chr3:49490149 A/C cg06212747 chr3:49208901 KLHDC8B 0.44 5.85 0.3 1.13e-8 Resting heart rate; LIHC cis rs2836950 0.545 rs2836959 chr21:40623668 T/G cg06238570 chr21:40685208 BRWD1 -0.46 -7.48 -0.37 6.44e-13 Menarche (age at onset); LIHC cis rs12188164 0.812 rs10072668 chr5:422752 T/C cg10655629 chr5:480253 SLC9A3 0.36 5.82 0.3 1.32e-8 Cystic fibrosis severity; LIHC cis rs2404602 0.669 rs1875884 chr15:76638161 C/T cg03037974 chr15:76606532 NA 0.82 17.3 0.68 1.31e-48 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26386436 chr14:90084672 FOXN3 0.41 6.36 0.33 6.42e-10 Lung function (FEV1/FVC); LIHC trans rs9929218 0.906 rs33965787 chr16:68828173 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -8.01 -0.4 1.83e-14 Colorectal cancer; LIHC cis rs11864453 0.826 rs6499560 chr16:72147666 G/T cg01557791 chr16:72042693 DHODH 0.5 8.49 0.42 6.25e-16 Fibrinogen levels; LIHC cis rs1580019 0.813 rs2044839 chr7:32500805 A/C cg07520158 chr7:32535189 LSM5;AVL9 0.49 6.6 0.34 1.53e-10 Cognitive ability; LIHC cis rs7589728 1.000 rs75181745 chr2:88520408 C/T cg04511125 chr2:88470314 THNSL2 0.77 7.15 0.36 5.16e-12 Plasma clusterin levels; LIHC cis rs1018836 0.828 rs12547016 chr8:91563847 T/C cg16814680 chr8:91681699 NA -0.54 -8.41 -0.41 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2576037 0.526 rs607780 chr18:44417456 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.17 -0.36 4.52e-12 Personality dimensions; LIHC cis rs12995491 0.933 rs13023008 chr2:88530933 G/A cg24977027 chr2:88469347 THNSL2 -0.34 -5.94 -0.31 7.04e-9 Response to metformin (IC50); LIHC cis rs367615 0.879 rs4351197 chr5:108866667 A/G cg17395555 chr5:108820864 NA 0.35 7.14 0.36 5.67e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg07424592 chr7:64974309 NA 0.84 9.61 0.46 1.62e-19 Diabetic kidney disease; LIHC cis rs2204008 0.576 rs11519979 chr12:37999413 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs1005277 0.540 rs1814077 chr10:37992018 G/C cg25427524 chr10:38739819 LOC399744 -0.62 -11.91 -0.54 1.38e-27 Extrinsic epigenetic age acceleration; LIHC cis rs7937682 0.883 rs1784775 chr11:111472460 T/C cg09085632 chr11:111637200 PPP2R1B -0.93 -11.29 -0.52 2.55e-25 Primary sclerosing cholangitis; LIHC cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg27535305 chr1:53392650 SCP2 0.29 5.75 0.3 2.01e-8 Monocyte count; LIHC cis rs16912285 0.688 rs35683920 chr11:24358521 A/G ch.11.24196551F chr11:24239977 NA 0.68 7.73 0.39 1.2e-13 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs9368481 0.761 rs7775041 chr6:27009512 T/A cg18867708 chr6:26865862 GUSBL1 -0.55 -8.33 -0.41 1.99e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs2559856 1.000 rs10778139 chr12:102083202 C/T cg12924262 chr12:102091054 CHPT1 -0.5 -8.18 -0.4 5.75e-15 Blood protein levels; LIHC cis rs7534824 0.625 rs61780285 chr1:101357627 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 6.75 0.34 6.3e-11 Refractive astigmatism; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg14671364 chr1:107599128 PRMT6 -0.45 -6.55 -0.33 2.17e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.72 10.6 0.5 6.78e-23 Lymphocyte counts; LIHC cis rs875971 0.660 rs801217 chr7:66010577 C/T cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs2404602 0.684 rs10851888 chr15:76902506 C/T cg03037974 chr15:76606532 NA -0.6 -9.92 -0.47 1.52e-20 Blood metabolite levels; LIHC cis rs9457247 1.000 rs413232 chr6:167400972 G/A cg23791538 chr6:167370224 RNASET2 -0.65 -11.13 -0.52 9.48e-25 Crohn's disease; LIHC cis rs1577917 0.771 rs2842601 chr6:86330133 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -12.22 -0.55 9.98e-29 Response to antipsychotic treatment; LIHC cis rs240764 0.658 rs12210255 chr6:101187540 G/C cg12253828 chr6:101329408 ASCC3 -0.39 -5.95 -0.31 6.78e-9 Neuroticism; LIHC cis rs17102423 0.826 rs12887607 chr14:65596887 G/A cg11161011 chr14:65562177 MAX -0.48 -6.38 -0.33 5.72e-10 Obesity-related traits; LIHC cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg25894440 chr7:65020034 NA -0.54 -6.12 -0.31 2.54e-9 Diabetic kidney disease; LIHC cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg00800038 chr16:89945340 TCF25 -0.67 -10.78 -0.5 1.64e-23 Skin colour saturation; LIHC cis rs116095464 0.558 rs10057299 chr5:242135 C/T cg22857025 chr5:266934 NA -1.48 -18.17 -0.7 4.09e-52 Breast cancer; LIHC cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg19318889 chr4:1322082 MAEA 0.47 6.55 0.33 2.13e-10 Obesity-related traits; LIHC cis rs1046896 0.503 rs12947062 chr17:80686370 A/G cg00809820 chr17:80708513 TBCD;FN3K -0.33 -5.74 -0.3 2.08e-8 Glycated hemoglobin levels; LIHC cis rs10838687 0.736 rs2242262 chr11:47266540 G/T cg26139080 chr11:47293733 MADD -0.42 -5.89 -0.3 8.99e-9 Proinsulin levels; LIHC cis rs79149102 0.579 rs12592477 chr15:75292699 C/T cg09165964 chr15:75287851 SCAMP5 -0.59 -7.75 -0.39 1.04e-13 Lung cancer; LIHC cis rs861318 0.640 rs3768515 chr1:159010232 T/G cg11003133 chr1:159046391 AIM2 -0.35 -6.74 -0.34 6.69e-11 Obesity-related traits; LIHC cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.57 -0.46 2.31e-19 Initial pursuit acceleration; LIHC cis rs2382817 0.580 rs6756265 chr2:219095554 G/A cg20019365 chr2:219134978 PNKD;AAMP -0.74 -12.22 -0.55 9.39e-29 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg08888203 chr3:10149979 C3orf24 0.56 6.37 0.33 6.04e-10 Alzheimer's disease; LIHC cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 11.99 0.54 6.68e-28 Alzheimer's disease; LIHC cis rs3741404 0.825 rs7111753 chr11:63942189 A/G cg18225595 chr11:63971243 STIP1 0.68 10.77 0.5 1.74e-23 Platelet count; LIHC cis rs3749237 0.576 rs62259939 chr3:49386047 G/A cg07636037 chr3:49044803 WDR6 0.53 7.97 0.4 2.4e-14 Resting heart rate; LIHC cis rs7617773 0.780 rs13082859 chr3:48344675 C/T cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs9902453 0.904 rs4077465 chr17:28300144 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.71 0.6 2.17e-34 Coffee consumption (cups per day); LIHC cis rs600806 0.815 rs4970730 chr1:109979526 T/C cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.16 -0.36 4.83e-12 Intelligence (multi-trait analysis); LIHC cis rs9612 1.000 rs346528 chr19:44259232 G/T cg08581076 chr19:44259116 C19orf61 0.7 8.94 0.44 2.49e-17 Exhaled nitric oxide output; LIHC cis rs769267 1.000 rs8103197 chr19:19443466 C/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.27 -0.32 1.11e-9 Tonsillectomy; LIHC cis rs12477438 0.520 rs6741772 chr2:99738961 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.38 0.77 5.56e-69 Chronic sinus infection; LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg12516959 chr21:47718080 NA 0.36 5.89 0.3 9.46e-9 Testicular germ cell tumor; LIHC cis rs8114671 0.742 rs6058161 chr20:33620026 C/T cg07148914 chr20:33460835 GGT7 -0.55 -8.33 -0.41 2e-15 Height; LIHC cis rs7772486 0.875 rs1330939 chr6:146308518 T/A cg13319975 chr6:146136371 FBXO30 -0.36 -6.05 -0.31 3.73e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6840360 0.571 rs72728182 chr4:152487027 T/C cg22705602 chr4:152727874 NA -0.34 -6.52 -0.33 2.59e-10 Intelligence (multi-trait analysis); LIHC cis rs1997103 0.871 rs6956733 chr7:55393032 A/C cg17469321 chr7:55412551 NA 0.46 6.67 0.34 1.05e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs11864453 0.713 rs12708927 chr16:72126165 C/T cg16558253 chr16:72132732 DHX38 -0.51 -8.1 -0.4 9.86e-15 Fibrinogen levels; LIHC cis rs4006360 0.553 rs71383383 chr17:39318172 T/A cg26521011 chr17:39394147 KRTAP9-8;KRTAP9-9 0.23 5.73 0.3 2.2e-8 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg21448741 chr8:58168803 NA 0.35 6.09 0.31 3.02e-9 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg16606324 chr3:10149918 C3orf24 0.49 5.76 0.3 1.88e-8 Alzheimer's disease; LIHC cis rs9790314 0.540 rs35462273 chr3:160991877 C/T cg03342759 chr3:160939853 NMD3 -0.66 -9.89 -0.47 1.91e-20 Morning vs. evening chronotype; LIHC cis rs72653721 0.838 rs3778166 chr6:11033164 A/G cg13562911 chr6:11044106 ELOVL2 -0.5 -7.17 -0.36 4.78e-12 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs2304069 0.954 rs216125 chr5:149428395 C/G cg12661370 chr5:149340060 SLC26A2 0.49 5.75 0.3 1.94e-8 HIV-1 control; LIHC cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg09455208 chr3:40491958 NA 0.32 6.5 0.33 2.77e-10 Renal cell carcinoma; LIHC cis rs6500602 0.702 rs9929475 chr16:4540885 C/T cg08645402 chr16:4508243 NA -0.39 -6.89 -0.35 2.7e-11 Schizophrenia; LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs8005677 0.926 rs34344888 chr14:23387585 A/G cg07971674 chr14:23388846 RBM23 -0.41 -5.84 -0.3 1.22e-8 Cognitive ability (multi-trait analysis); LIHC cis rs3740540 0.530 rs4297414 chr10:126292116 T/G cg04949429 chr10:126290192 LHPP 0.45 7.34 0.37 1.56e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs1005277 0.579 rs2472182 chr10:38388865 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs12791968 0.765 rs12794846 chr11:44998943 C/T cg11846598 chr11:44996168 LOC221122 0.39 6.47 0.33 3.47e-10 Inhibitory control; LIHC cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg06634786 chr22:41940651 POLR3H -0.81 -8.83 -0.43 5.65e-17 Vitiligo; LIHC cis rs9303401 0.659 rs7210700 chr17:56668186 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.92 12.29 0.55 5.1e-29 Cognitive test performance; LIHC cis rs4713118 0.513 rs149950 chr6:28033039 T/G cg23485639 chr6:28045615 ZNF165 0.38 5.77 0.3 1.75e-8 Parkinson's disease; LIHC cis rs7131987 0.683 rs12366505 chr12:29474110 C/T cg00204748 chr12:29376779 FAR2 0.4 7.49 0.38 5.92e-13 QT interval; LIHC cis rs6933660 0.720 rs6936936 chr6:151753395 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 7.5 0.38 5.41e-13 Menarche (age at onset); LIHC cis rs769267 0.965 rs12977937 chr19:19429975 C/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.29 0.32 9.8e-10 Tonsillectomy; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16411256 chr8:27348931 EPHX2 0.38 6.94 0.35 1.92e-11 Cognitive function; LIHC cis rs6570726 0.791 rs12208812 chr6:145900924 T/G cg05347473 chr6:146136440 FBXO30 0.38 5.92 0.3 7.87e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.545 rs1909508 chr7:65766353 G/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.38 7.68 0.38 1.69e-13 Aortic root size; LIHC cis rs1538970 0.774 rs67683090 chr1:45977803 T/G cg24296786 chr1:45957014 TESK2 -0.45 -6.21 -0.32 1.53e-9 Platelet count; LIHC cis rs151997 0.853 rs6882235 chr5:50260139 T/C cg06027927 chr5:50259733 NA 0.62 8.49 0.42 6.43e-16 Callous-unemotional behaviour; LIHC cis rs9916302 0.904 rs11655531 chr17:37697959 T/C cg07936489 chr17:37558343 FBXL20 -0.82 -13.07 -0.58 6.17e-32 Glomerular filtration rate (creatinine); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08575399 chr20:60719638 PSMA7;SS18L1 0.4 6.44 0.33 4.09e-10 Pancreatic cancer; LIHC cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg07424592 chr7:64974309 NA 0.81 9.51 0.46 3.46e-19 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.11 -0.36 7.03e-12 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg18306943 chr3:40428807 ENTPD3 0.42 7.24 0.36 2.94e-12 Renal cell carcinoma; LIHC cis rs6546550 0.935 rs1377995 chr2:70064155 C/G cg02498382 chr2:70120550 SNRNP27 -0.39 -6.54 -0.33 2.26e-10 Prevalent atrial fibrillation; LIHC trans rs1499614 0.803 rs1796229 chr7:66119661 G/A cg10756647 chr7:56101905 PSPH 1.01 11.86 0.54 2.03e-27 Gout; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg27310827 chr1:1163671 SDF4 0.46 6.08 0.31 3.16e-9 Hip circumference; LIHC cis rs6430585 0.702 rs746857 chr2:136554890 G/A cg07169764 chr2:136633963 MCM6 -1.12 -16.53 -0.67 1.58e-45 Corneal structure; LIHC cis rs7107174 1.000 rs2511157 chr11:77972632 G/A cg02023728 chr11:77925099 USP35 0.5 9.38 0.45 9.68e-19 Testicular germ cell tumor; LIHC trans rs17685 0.753 rs10085567 chr7:75734206 A/C cg19862616 chr7:65841803 NCRNA00174 0.89 17.58 0.69 9.77e-50 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs332507 0.711 rs3772793 chr3:124405723 A/G cg05980111 chr3:124395277 KALRN 0.45 6.88 0.35 2.9100000000000002e-11 Plateletcrit; LIHC cis rs1577917 0.958 rs12193904 chr6:86452703 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.09 -0.51 1.29e-24 Response to antipsychotic treatment; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg15382696 chr6:118971807 C6orf204 0.62 6.45 0.33 3.75e-10 Diastolic blood pressure; LIHC cis rs12313068 0.709 rs11064912 chr12:110505699 A/T cg12870014 chr12:110450643 ANKRD13A -0.82 -11.02 -0.51 2.35e-24 Intelligence (multi-trait analysis); LIHC cis rs1348850 0.526 rs2178017 chr2:178374788 G/T cg27490568 chr2:178487706 NA 1.11 12.08 0.55 3.25e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs939574 0.722 rs72955435 chr2:220087354 A/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.87 6.36 0.33 6.41e-10 Platelet distribution width; LIHC cis rs10791097 0.694 rs6590520 chr11:130747386 C/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.79e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10504229 0.565 rs7010503 chr8:58147127 G/A cg02290350 chr8:58132656 NA 0.44 9.49 0.46 4.2e-19 Developmental language disorder (linguistic errors); LIHC cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.84 8.59 0.42 3.12e-16 Platelet count; LIHC cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg12419862 chr22:24373484 LOC391322 -0.69 -10.36 -0.49 4.73e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg21724239 chr8:58056113 NA 0.57 7.45 0.37 7.56e-13 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.522 rs9418276 chr10:37940116 G/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.53 -0.46 2.98e-19 Extrinsic epigenetic age acceleration; LIHC cis rs3741404 0.791 rs7102177 chr11:63909228 T/C cg18225595 chr11:63971243 STIP1 0.68 10.9 0.51 5.88e-24 Platelet count; LIHC cis rs6750047 0.585 rs62136319 chr2:38272950 G/A cg07380506 chr2:38303506 CYP1B1 0.6 7.82 0.39 6.51e-14 Cutaneous malignant melanoma;Melanoma; LIHC cis rs10504229 0.679 rs10504217 chr8:58037522 A/G cg02290350 chr8:58132656 NA 0.31 7.15 0.36 5.41e-12 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.66 0.38 1.89e-13 Prudent dietary pattern; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg05560165 chr5:133450315 TCF7 -0.43 -6.2 -0.32 1.62e-9 Systolic blood pressure; LIHC cis rs9457247 0.663 rs6456143 chr6:167415440 C/A cg12798992 chr6:167411361 FGFR1OP 0.52 8.64 0.42 2.12e-16 Crohn's disease; LIHC cis rs7552404 1.000 rs7552404 chr1:76135946 A/G cg03433033 chr1:76189801 ACADM 0.69 10.02 0.48 6.72e-21 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1555399 0.901 rs7155830 chr14:67979557 A/G cg16224230 chr14:67978224 TMEM229B 0.25 6.25 0.32 1.23e-9 Parkinson's disease; LIHC cis rs35306767 0.622 rs66462130 chr10:1022108 C/T cg26597838 chr10:835615 NA 0.93 8.35 0.41 1.71e-15 Eosinophil percentage of granulocytes; LIHC trans rs2262909 0.962 rs4932952 chr19:22246788 G/A cg05197062 chr11:11642011 GALNTL4 0.42 6.08 0.31 3.17e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs10078 0.571 rs2561664 chr5:459793 T/C cg07599136 chr5:415885 AHRR 0.77 12.61 0.56 3.37e-30 Fat distribution (HIV); LIHC cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg25894440 chr7:65020034 NA 0.54 6.22 0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs6138458 1.000 rs6138458 chr20:24973769 C/T cg26195577 chr20:24973756 C20orf3 1.18 15.74 0.65 2.28e-42 Blood protein levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22098324 chr2:232645906 PDE6D -0.41 -6.3 -0.32 9.41e-10 Pancreatic cancer; LIHC cis rs4563143 0.514 rs112651366 chr19:29299704 A/T cg04546413 chr19:29218101 NA 0.5 8.32 0.41 2.17e-15 Methadone dose in opioid dependence; LIHC cis rs7208859 0.673 rs12103588 chr17:29197460 C/T cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg10210624 chr19:58662595 ZNF329 0.74 7.5 0.38 5.38e-13 Cholesterol, total; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg25974723 chr19:50119415 PRR12 0.4 6.05 0.31 3.74e-9 Alopecia areata; LIHC cis rs2455799 0.613 rs4685258 chr3:15792315 G/A cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC trans rs1005277 0.579 rs932538 chr10:38381314 T/C cg27523141 chr10:43048294 ZNF37B 0.37 6.4 0.33 5.12e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9814567 0.806 rs7648616 chr3:134318074 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg05368731 chr17:41323189 NBR1 0.73 12.36 0.56 2.82e-29 Menopause (age at onset); LIHC trans rs1814175 0.645 rs1851845 chr11:49982396 C/T cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9393692 0.905 rs7761298 chr6:26278436 C/T cg13736514 chr6:26305472 NA -0.37 -6.23 -0.32 1.34e-9 Educational attainment; LIHC cis rs1799949 0.930 rs2298861 chr17:41176831 G/A cg25072359 chr17:41440525 NA 0.37 5.95 0.31 6.7e-9 Menopause (age at onset); LIHC cis rs11105298 0.786 rs10858867 chr12:89851166 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.54 -0.38 4.24e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs10876993 0.928 rs1678532 chr12:58055197 T/G cg15848620 chr12:58087721 OS9 -0.55 -7.47 -0.37 6.68e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg17747265 chr1:1875780 NA -0.58 -11.32 -0.52 1.98e-25 Body mass index; LIHC cis rs2842992 0.672 rs4708845 chr6:160219601 T/G cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.78 0.57 7.93e-31 Age-related macular degeneration (geographic atrophy); LIHC cis rs35110281 0.744 rs230646 chr21:44918788 A/G cg01579765 chr21:45077557 HSF2BP -0.33 -5.87 -0.3 1.06e-8 Mean corpuscular volume; LIHC trans rs76747430 0.528 rs5750913 chr22:40640285 A/G cg14868726 chr18:2571660 METTL4;NDC80 -0.51 -6.12 -0.31 2.57e-9 Facial morphology (factor 20); LIHC cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg03806693 chr22:41940476 POLR3H 1.09 13.07 0.58 6.34e-32 Vitiligo; LIHC cis rs66573146 0.831 rs6851488 chr4:6987412 C/T cg00086871 chr4:6988644 TBC1D14 0.79 5.86 0.3 1.06e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs10464366 0.746 rs6945547 chr7:39145389 C/G cg10621924 chr7:39171070 POU6F2 0.4 6.27 0.32 1.08e-9 IgG glycosylation; LIHC cis rs7116495 0.737 rs2852370 chr11:71558679 G/C cg26138937 chr11:71823887 C11orf51 0.65 6.36 0.33 6.63e-10 Severe influenza A (H1N1) infection; LIHC cis rs12479064 0.724 rs62153852 chr2:99934713 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.52 -7.09 -0.36 7.52e-12 Chronic sinus infection; LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg08677398 chr8:58056175 NA 0.4 6.09 0.31 3.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg00656387 chr3:40428638 ENTPD3 -0.46 -7.55 -0.38 4.03e-13 Renal cell carcinoma; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07573366 chr7:32802765 NA 0.23 6.05 0.31 3.91e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg11644478 chr21:40555479 PSMG1 -0.37 -5.85 -0.3 1.17e-8 Menarche (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg05061393 chr2:220043337 FAM134A 0.5 6.59 0.34 1.68e-10 Lung function (FEV1/FVC); LIHC cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg10217327 chr6:118973057 C6orf204 0.65 6.43 0.33 4.36e-10 Diastolic blood pressure; LIHC cis rs7647973 0.587 rs10452032 chr3:49680973 G/A cg03060546 chr3:49711283 APEH 0.61 7.03 0.36 1.09e-11 Menarche (age at onset); LIHC cis rs4951018 0.526 rs4601639 chr1:205656583 A/G cg17723122 chr1:205641542 SLC45A3 0.39 6.38 0.33 5.86e-10 Prostate-specific antigen levels; LIHC cis rs1878931 0.501 rs4785934 chr16:3419934 G/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.71 10.56 0.5 9.12e-23 Body mass index (adult); LIHC cis rs780096 0.587 rs4665969 chr2:27574953 C/T cg21747090 chr2:27597821 SNX17 0.46 7.16 0.36 5.06e-12 Total body bone mineral density; LIHC cis rs10789491 1.000 rs601060 chr1:47139580 C/G cg15501359 chr1:47185051 KIAA0494 -0.77 -11.02 -0.51 2.29e-24 Response to hepatitis C treatment; LIHC cis rs611744 0.934 rs1452021 chr8:109207886 A/G cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs116095464 0.558 rs62346508 chr5:203668 T/C cg22496380 chr5:211416 CCDC127 -1.19 -10.56 -0.5 9.27e-23 Breast cancer; LIHC cis rs2836950 0.545 rs11700813 chr21:40517469 T/G cg11890956 chr21:40555474 PSMG1 -0.45 -7.48 -0.38 6.22e-13 Menarche (age at onset); LIHC cis rs908922 0.743 rs10888499 chr1:152532742 C/A cg20991723 chr1:152506922 NA 0.39 5.71 0.3 2.42e-8 Hair morphology; LIHC cis rs1555322 0.530 rs6060341 chr20:33863633 C/T cg17927777 chr20:33865990 NA -0.55 -6.49 -0.33 3.04e-10 Attention deficit hyperactivity disorder; LIHC cis rs11098699 0.821 rs13114886 chr4:124217302 T/A cg09941581 chr4:124220074 SPATA5 0.33 6.66 0.34 1.1e-10 Mosquito bite size; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.49 -6.88 -0.35 2.81e-11 Lymphocyte counts; LIHC cis rs9948 0.786 rs62156226 chr2:97417108 G/A cg01990225 chr2:97406019 LMAN2L -0.72 -6.23 -0.32 1.37e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs600806 0.714 rs12137189 chr1:110013215 A/G cg10127483 chr1:110009974 SYPL2 0.49 6.38 0.33 5.76e-10 Intelligence (multi-trait analysis); LIHC cis rs2976388 0.566 rs6998746 chr8:143802456 A/C cg06565975 chr8:143823917 SLURP1 0.39 7.43 0.37 9.01e-13 Urinary tract infection frequency; LIHC cis rs2304069 0.545 rs7445660 chr5:149413610 A/C cg12661370 chr5:149340060 SLC26A2 0.53 7.79 0.39 8.37e-14 HIV-1 control; LIHC cis rs644799 0.710 rs12272061 chr11:95524067 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 12.7 0.57 1.59e-30 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs4920343 0.671 rs509990 chr1:19090175 T/C cg19637330 chr1:19110922 NA 0.35 6.36 0.33 6.55e-10 Knee osteoarthritis; LIHC cis rs1419980 0.673 rs10845432 chr12:7728131 T/C cg10578777 chr12:7781093 NA 0.48 8.38 0.41 1.35e-15 HDL cholesterol levels; LIHC cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC trans rs2727020 0.566 rs10839234 chr11:49185524 C/T cg15704280 chr7:45808275 SEPT13 -0.89 -16.51 -0.67 1.97e-45 Coronary artery disease; LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg04234412 chr22:24373322 LOC391322 -0.67 -9.92 -0.47 1.47e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3018712 0.505 rs7102308 chr11:68413230 T/C cg16797656 chr11:68205561 LRP5 -0.46 -6.01 -0.31 4.76e-9 Total body bone mineral density; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg24209194 chr3:40518798 ZNF619 0.56 8.15 0.4 6.87e-15 Renal cell carcinoma; LIHC cis rs7208859 0.623 rs11657391 chr17:29194287 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6570726 0.599 rs9403725 chr6:145897622 A/T cg23711669 chr6:146136114 FBXO30 -0.64 -9.34 -0.45 1.29e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs910316 1.000 rs7145159 chr14:75583268 A/G cg08847533 chr14:75593920 NEK9 0.9 20.49 0.74 1.94e-61 Height; LIHC cis rs34375054 0.526 rs2343638 chr12:125677122 G/C cg25124228 chr12:125621409 AACS -0.45 -7.86 -0.39 5.1e-14 Post bronchodilator FEV1/FVC ratio; LIHC cis rs7131987 0.934 rs2216854 chr12:29423460 G/A cg05697976 chr12:29376483 FAR2 0.32 6.64 0.34 1.24e-10 QT interval; LIHC cis rs8060686 0.545 rs12600062 chr16:68287544 C/A cg05110241 chr16:68378359 PRMT7 -0.62 -6.87 -0.35 3.08e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs4268898 0.662 rs2288074 chr2:24413595 C/T cg06627628 chr2:24431161 ITSN2 -0.69 -8.98 -0.44 1.9e-17 Asthma; LIHC cis rs7213347 0.780 rs9892016 chr17:2146422 A/G cg15816464 chr17:2026533 SMG6 0.46 8.22 0.41 4.34e-15 Total body bone mineral density; LIHC cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg23262073 chr20:60523788 NA -0.3 -6.22 -0.32 1.44e-9 Body mass index; LIHC cis rs1008375 0.932 rs9283698 chr4:17662471 T/C cg16339924 chr4:17578868 LAP3 0.51 6.65 0.34 1.13e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2380220 0.808 rs72922390 chr6:95934317 G/A cg04719120 chr6:96025338 MANEA -0.59 -6.21 -0.32 1.53e-9 Behavioural disinhibition (generation interaction); LIHC trans rs8073060 0.544 rs225252 chr17:33952401 G/A cg19694781 chr19:47549865 TMEM160 -1.24 -13.34 -0.59 5.73e-33 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC trans rs1814175 0.646 rs61904497 chr11:49883449 A/T cg15704280 chr7:45808275 SEPT13 -0.95 -19.96 -0.73 2.55e-59 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg15423853 chr12:11323943 PRR4;PRH1 0.45 6.19 0.32 1.76e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7173389 0.560 rs7174643 chr15:73680301 A/C cg01796676 chr15:73680284 NA 0.53 8.64 0.42 2.12e-16 Resting heart rate; LIHC cis rs6582630 0.555 rs35284307 chr12:38509999 T/G cg26384229 chr12:38710491 ALG10B 0.7 9.97 0.47 1.01e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs1670533 0.932 rs13140341 chr4:1054235 T/C cg27284194 chr4:1044797 NA 0.6 8.89 0.43 3.56e-17 Recombination rate (females); LIHC cis rs798554 0.797 rs798493 chr7:2798731 A/G cg19346786 chr7:2764209 NA -0.48 -7.2 -0.36 3.93e-12 Height; LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg26338869 chr17:61819248 STRADA 0.6 8.78 0.43 8.04e-17 Prudent dietary pattern; LIHC trans rs7677751 0.747 rs1800809 chr4:55093914 A/G cg17183009 chr3:120277827 NA 0.52 6.09 0.31 3.02e-9 Corneal astigmatism; LIHC cis rs2404602 0.583 rs4381566 chr15:76589262 A/G cg03037974 chr15:76606532 NA 0.9 23.51 0.79 2.01e-73 Blood metabolite levels; LIHC cis rs17685 0.712 rs1859794 chr7:75821544 G/A cg04610667 chr7:75704037 NA -0.33 -5.98 -0.31 5.64e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs765787 0.530 rs28897155 chr15:45533974 T/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs3789045 0.774 rs4252697 chr1:204501383 C/T cg17419461 chr1:204415978 PIK3C2B -0.43 -6.74 -0.34 6.58e-11 Educational attainment (college completion); LIHC cis rs2153535 0.580 rs6929206 chr6:8447961 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.99 0.4 2.05e-14 Motion sickness; LIHC cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg13409248 chr3:40428643 ENTPD3 0.48 8.18 0.4 5.67e-15 Renal cell carcinoma; LIHC cis rs2836950 0.840 rs12482317 chr21:40588241 A/G cg11890956 chr21:40555474 PSMG1 -0.42 -6.11 -0.31 2.68e-9 Menarche (age at onset); LIHC cis rs6754311 0.628 rs309811 chr2:136625602 A/G cg17750252 chr2:136567154 LCT 0.35 6.41 0.33 4.71e-10 Mosquito bite size; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.8 14.94 0.63 3.29e-39 Prudent dietary pattern; LIHC trans rs875971 1.000 rs6979382 chr7:65886375 C/T cg10756647 chr7:56101905 PSPH 0.45 6.64 0.34 1.2e-10 Aortic root size; LIHC cis rs1816752 0.875 rs59531061 chr13:25081435 C/T cg22771759 chr13:24902376 NA 0.31 6.34 0.32 7.45e-10 Obesity-related traits; LIHC cis rs11758351 1.000 rs76722536 chr6:26192946 C/G cg06951627 chr6:26196580 NA 0.52 5.87 0.3 1.01e-8 Gout;Renal underexcretion gout; LIHC cis rs5769707 0.656 rs135878 chr22:50014369 T/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.24 -0.41 3.78e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2153535 0.580 rs4960411 chr6:8438231 C/G cg21535247 chr6:8435926 SLC35B3 0.61 7.88 0.39 4.36e-14 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15401922 chr6:157802439 ZDHHC14 0.53 7.5 0.38 5.63e-13 Lung function (FEV1/FVC); LIHC cis rs17685 0.753 rs9691174 chr7:75790405 T/C cg01364799 chr7:75623366 TMEM120A -0.52 -7.84 -0.39 5.62e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10484885 0.824 rs72919976 chr6:90526686 C/G cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.69 -0.34 9.39e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs11122272 0.735 rs2011357 chr1:231480208 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.92 -0.51 5.17e-24 Hemoglobin concentration; LIHC cis rs9470366 0.883 rs9462210 chr6:36628953 G/A cg08179530 chr6:36648295 CDKN1A 0.56 6.91 0.35 2.38e-11 QRS duration; LIHC cis rs769267 1.000 rs8103197 chr19:19443466 C/T cg03709012 chr19:19516395 GATAD2A -0.92 -16.02 -0.65 1.72e-43 Tonsillectomy; LIHC cis rs1046896 1.000 rs9909940 chr17:80689036 C/T cg02711726 chr17:80685570 FN3KRP -0.58 -11.48 -0.53 5.23e-26 Glycated hemoglobin levels; LIHC trans rs783540 0.500 rs1313494 chr15:83274279 C/T cg18393722 chr15:85113863 UBE2QP1 -0.41 -6.39 -0.33 5.34e-10 Schizophrenia; LIHC cis rs11690462 0.794 rs2384364 chr2:26541427 C/G cg26119090 chr2:26468346 HADHA;HADHB 0.38 5.79 0.3 1.58e-8 Coronary artery disease; LIHC cis rs17685 0.697 rs2302437 chr7:75677016 G/A cg04610667 chr7:75704037 NA 0.35 6.14 0.32 2.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1577917 1.000 rs1577917 chr6:86691940 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.38 -0.33 5.66e-10 Response to antipsychotic treatment; LIHC cis rs875971 0.638 rs801205 chr7:66022144 C/A cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC cis rs34779708 0.931 rs2384283 chr10:35326789 G/A cg03585969 chr10:35415529 CREM 0.86 12.97 0.57 1.52e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg12310025 chr6:25882481 NA -0.53 -6.52 -0.33 2.54e-10 Intelligence (multi-trait analysis); LIHC cis rs7618501 0.633 rs11130234 chr3:50024758 G/T cg21467203 chr3:49911342 NA -0.43 -7.74 -0.39 1.17e-13 Intelligence (multi-trait analysis); LIHC cis rs9868809 0.505 rs9811027 chr3:48725014 G/C cg07636037 chr3:49044803 WDR6 -0.68 -7.34 -0.37 1.53e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs1165668 0.785 rs2439624 chr12:104313715 T/C cg21863207 chr12:104234989 NT5DC3 0.4 6.4 0.33 5.22e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs11098499 0.866 rs12513310 chr4:120288039 T/A cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs9948 0.655 rs62156210 chr2:97393736 A/T cg01990225 chr2:97406019 LMAN2L -0.82 -6.33 -0.32 7.9e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs1355223 0.902 rs1901831 chr11:34725175 C/T cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.43 -0.33 4.36e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs9486719 0.741 rs976356 chr6:96849437 T/A cg06623918 chr6:96969491 KIAA0776 0.71 6.87 0.35 2.96e-11 Migraine;Coronary artery disease; LIHC cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg18654377 chr3:49208889 KLHDC8B -0.49 -5.81 -0.3 1.45e-8 Menarche (age at onset); LIHC cis rs1728785 1.000 rs1182968 chr16:68573945 C/T cg02972257 chr16:68554789 NA -0.55 -6.34 -0.32 7.48e-10 Ulcerative colitis; LIHC cis rs7131987 0.903 rs11050163 chr12:29420398 C/T cg21486233 chr12:29375141 FAR2 0.31 6.07 0.31 3.46e-9 QT interval; LIHC cis rs11711311 0.955 rs7617313 chr3:113391740 T/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.36 6.18 0.32 1.8e-9 IgG glycosylation; LIHC cis rs4820294 0.646 rs9622675 chr22:38053665 G/T cg26138144 chr22:38071188 LGALS1 0.42 7.76 0.39 1e-13 Fat distribution (HIV); LIHC cis rs2257205 0.667 rs8077548 chr17:56690848 T/C cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs1538970 0.962 rs9429077 chr1:45820667 C/A cg05343316 chr1:45956843 TESK2 0.59 8.96 0.44 2.16e-17 Platelet count; LIHC cis rs1005277 0.579 rs2474584 chr10:38416389 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.96 -0.31 6.38e-9 Extrinsic epigenetic age acceleration; LIHC cis rs55823223 0.564 rs936396 chr17:73846829 C/G cg10935138 chr17:73851978 WBP2 0.69 9.24 0.45 2.74e-18 Psoriasis; LIHC cis rs9682041 1.000 rs4955588 chr3:170072864 C/A cg11886554 chr3:170076028 SKIL 0.75 6.37 0.33 6.22e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs7481584 0.624 rs397919 chr11:3063094 A/C cg25174290 chr11:3078921 CARS -0.41 -6.0 -0.31 4.9e-9 Calcium levels; LIHC cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg06634786 chr22:41940651 POLR3H 0.83 8.94 0.44 2.53e-17 Vitiligo; LIHC cis rs10751667 1.000 rs7396798 chr11:970510 G/T ch.11.42038R chr11:967971 AP2A2 0.61 11.47 0.53 5.46e-26 Alzheimer's disease (late onset); LIHC cis rs10791323 0.559 rs10750548 chr11:133729469 A/G cg06766960 chr11:133703094 NA -0.65 -11.0 -0.51 2.74e-24 Childhood ear infection; LIHC cis rs2274273 0.870 rs2016931 chr14:55842332 C/G cg01864836 chr14:55583639 NA -0.37 -6.66 -0.34 1.07e-10 Protein biomarker; LIHC cis rs6089584 0.888 rs6061966 chr20:60607936 C/G cg23262073 chr20:60523788 NA -0.29 -5.97 -0.31 6.03e-9 Body mass index; LIHC cis rs1008375 0.966 rs2315645 chr4:17579678 G/C cg16339924 chr4:17578868 LAP3 0.46 6.31 0.32 8.79e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7618501 1.000 rs7374183 chr3:49785133 G/A cg24110177 chr3:50126178 RBM5 0.42 6.49 0.33 3.1e-10 Intelligence (multi-trait analysis); LIHC cis rs151997 0.962 rs26088 chr5:50172670 T/G cg06027927 chr5:50259733 NA 0.57 7.59 0.38 3.13e-13 Callous-unemotional behaviour; LIHC cis rs4631830 0.932 rs4581397 chr10:51532367 A/G cg20129853 chr10:51489980 NA -0.41 -8.99 -0.44 1.66e-17 Prostate-specific antigen levels; LIHC cis rs853679 0.517 rs9393896 chr6:28127703 C/T cg16479474 chr6:28041457 NA 0.46 6.46 0.33 3.5e-10 Depression; LIHC cis rs763014 0.966 rs15564 chr16:677854 G/T cg00908189 chr16:619842 PIGQ 0.82 13.54 0.59 9.68e-34 Height; LIHC cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg06481639 chr22:41940642 POLR3H -0.65 -6.69 -0.34 9.09e-11 Vitiligo; LIHC cis rs4908768 0.501 rs6577491 chr1:8574972 G/T cg20416874 chr1:8611966 RERE -0.65 -13.4 -0.59 3.26e-33 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs6062302 0.522 rs11696202 chr20:62246292 G/C cg06363034 chr20:62225388 GMEB2 -0.45 -7.71 -0.38 1.4e-13 Glioblastoma; LIHC cis rs6598955 1.000 rs6598955 chr1:26619649 C/T cg04990556 chr1:26633338 UBXN11 0.75 12.75 0.57 1.03e-30 Obesity-related traits; LIHC cis rs10751667 0.666 rs7950967 chr11:955638 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.09 0.48 4.1e-21 Alzheimer's disease (late onset); LIHC cis rs911119 1.000 rs5030707 chr20:23618656 C/G cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs10744422 0.925 rs2292132 chr12:123332834 T/C cg22842854 chr12:123319900 HIP1R -0.74 -9.76 -0.47 5.03e-20 Schizophrenia; LIHC cis rs72627123 0.656 rs765720 chr14:74541326 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.85 8.25 0.41 3.52e-15 Morning vs. evening chronotype; LIHC cis rs7927771 1.000 rs7120333 chr11:47817441 C/T cg20135002 chr11:47629003 NA -0.54 -9.17 -0.44 4.7e-18 Subjective well-being; LIHC cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg22963979 chr7:1858916 MAD1L1 -0.38 -5.98 -0.31 5.53e-9 Bipolar disorder and schizophrenia; LIHC trans rs4650994 0.525 rs4650991 chr1:178511165 C/T cg05059571 chr16:84539110 KIAA1609 -0.45 -7.54 -0.38 4.25e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg23131131 chr22:24373011 LOC391322 -0.57 -8.1 -0.4 1.01e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs970821 1.000 rs1946584 chr8:124750585 G/A cg00283535 chr8:124749564 ANXA13 0.35 5.88 0.3 9.98e-9 Breast cancer; LIHC trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg26692224 chr17:62915920 LRRC37A3 -0.71 -6.8 -0.35 4.75e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2580764 0.566 rs2968794 chr2:55290651 C/G cg09592903 chr2:55203963 RTN4 -0.62 -11.65 -0.53 1.2e-26 Mean platelet volume; LIHC cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg25072359 chr17:41440525 NA 0.38 6.2 0.32 1.67e-9 Menopause (age at onset); LIHC cis rs9733 0.596 rs2867300 chr1:150666990 C/G cg13175981 chr1:150552382 MCL1 -0.44 -6.16 -0.32 2.08e-9 Tonsillectomy; LIHC cis rs7927592 0.956 rs12271290 chr11:68326236 A/G cg20283391 chr11:68216788 NA 0.51 7.78 0.39 8.52e-14 Total body bone mineral density; LIHC cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg22907277 chr7:1156413 C7orf50 0.51 7.87 0.39 4.79e-14 Longevity;Endometriosis; LIHC cis rs9419702 0.614 rs4897816 chr10:133533646 G/A cg04492858 chr10:133558786 NA 0.44 6.42 0.33 4.59e-10 Survival in rectal cancer; LIHC cis rs666930 0.519 rs532303 chr1:120265444 A/G cg19096424 chr1:120255104 PHGDH 0.89 11.63 0.53 1.48e-26 Breast cancer; LIHC cis rs4332037 0.950 rs10267593 chr7:1937261 G/A cg23422044 chr7:1970798 MAD1L1 -0.56 -6.74 -0.34 6.94e-11 Bipolar disorder; LIHC cis rs6723226 0.739 rs2069213 chr2:32743084 C/T cg02381751 chr2:32503542 YIPF4 0.69 10.38 0.49 4.1e-22 Intelligence (multi-trait analysis); LIHC cis rs3008870 1.000 rs3008870 chr1:67418027 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.24 0.66 2.29e-44 Lymphocyte percentage of white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11383747 chr17:260000 C17orf97 0.55 8.38 0.41 1.39e-15 Pancreatic cancer; LIHC cis rs523522 0.962 rs10849757 chr12:120964014 G/A cg27279351 chr12:120934652 DYNLL1 0.67 11.96 0.54 8.68e-28 High light scatter reticulocyte count; LIHC cis rs4820294 0.961 rs62236664 chr22:38059427 T/C cg26138144 chr22:38071188 LGALS1 0.75 14.03 0.6 1.2e-35 Fat distribution (HIV); LIHC cis rs2303759 0.914 rs2288481 chr19:49878196 G/A cg22590775 chr19:49891494 CCDC155 0.47 7.56 0.38 3.87e-13 Multiple sclerosis; LIHC cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg16822855 chr3:40428330 ENTPD3 0.34 6.14 0.31 2.35e-9 Renal cell carcinoma; LIHC cis rs2242116 0.932 rs1531137 chr3:46943028 T/C cg23352942 chr3:46931381 PTH1R -0.33 -8.84 -0.43 4.97e-17 Birth weight; LIHC cis rs9399137 0.507 rs4289677 chr6:135275485 A/G cg24558204 chr6:135376177 HBS1L 0.61 10.61 0.5 6.15e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs9814567 1.000 rs1357762 chr3:134264859 A/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -6.01 -0.31 4.7e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs35883536 0.967 rs4908085 chr1:101087901 C/G cg14515779 chr1:101123966 NA -0.67 -12.51 -0.56 7.73e-30 Monocyte count; LIHC cis rs9457247 0.510 rs6456151 chr6:167471851 A/C cg07741184 chr6:167504864 NA 0.29 6.86 0.35 3.3e-11 Crohn's disease; LIHC cis rs10849893 0.557 rs6489812 chr12:121913559 T/A cg01154721 chr12:121881891 KDM2B 0.55 9.21 0.45 3.43e-18 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2239547 0.603 rs6789219 chr3:53098938 C/G cg11645453 chr3:52864694 ITIH4 0.28 7.01 0.35 1.28e-11 Schizophrenia; LIHC cis rs918629 0.798 rs6877821 chr5:95289502 C/T cg10483112 chr5:95245456 ELL2 -0.37 -6.48 -0.33 3.23e-10 IgG glycosylation; LIHC cis rs9814567 0.963 rs36006513 chr3:134291913 T/A cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.14 0.32 2.3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6973256 0.569 rs9649595 chr7:133385921 G/C cg10665199 chr7:133106180 EXOC4 0.36 6.2 0.32 1.6e-9 Intelligence (multi-trait analysis); LIHC cis rs929354 0.742 rs6956046 chr7:156962874 G/A cg17757837 chr7:157058334 UBE3C 0.74 12.11 0.55 2.47e-28 Body mass index; LIHC cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg12463550 chr7:65579703 CRCP 0.7 7.21 0.36 3.53e-12 Diabetic kidney disease; LIHC trans rs11295209 1 rs11295209 chr4:120480233 TA/T cg25214090 chr10:38739885 LOC399744 -0.38 -6.2 -0.32 1.66e-9 Plateletcrit; LIHC cis rs6570726 0.791 rs6570694 chr6:145911204 C/G cg23711669 chr6:146136114 FBXO30 0.7 11.65 0.53 1.22e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg16606324 chr3:10149918 C3orf24 0.54 6.07 0.31 3.48e-9 Alzheimer's disease; LIHC cis rs12286929 0.607 rs10891808 chr11:115071301 T/C cg04055981 chr11:115044050 NA -0.49 -7.57 -0.38 3.47e-13 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9858542 0.953 rs67216675 chr3:49493151 G/T cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg20295408 chr7:1910781 MAD1L1 -0.45 -6.67 -0.34 1.03e-10 Bipolar disorder and schizophrenia; LIHC cis rs3762637 0.943 rs9289198 chr3:122277160 G/T cg24169773 chr3:122142474 KPNA1 -0.45 -9.01 -0.44 1.49e-17 LDL cholesterol levels; LIHC cis rs2073300 0.609 rs6137920 chr20:23363436 C/T cg16736954 chr20:23401023 NAPB 0.7 8.02 0.4 1.68e-14 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg18252515 chr7:66147081 NA -1.29 -17.09 -0.68 9.12e-48 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs10744422 1.000 rs10744422 chr12:123336789 T/C cg07706471 chr12:123319906 HIP1R -0.63 -8.34 -0.41 1.89e-15 Schizophrenia; LIHC cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg11764359 chr7:65958608 NA 0.68 9.31 0.45 1.58e-18 Aortic root size; LIHC cis rs244293 0.965 rs244307 chr17:53211713 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06522697 chr10:121356224 TIAL1 -0.44 -6.55 -0.33 2.13e-10 Pancreatic cancer; LIHC cis rs11711311 1.000 rs2603793 chr3:113496418 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.95 -0.35 1.88e-11 IgG glycosylation; LIHC trans rs7504990 0.722 rs1030593 chr18:50374155 A/G cg08535148 chr4:26321143 RBPJ 0.56 7.07 0.36 8.97e-12 Gallbladder cancer; LIHC cis rs12477438 0.700 rs12467679 chr2:99654449 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.87 -0.51 7.79e-24 Chronic sinus infection; LIHC cis rs1552244 0.882 rs61429272 chr3:10037320 G/C cg13047869 chr3:10149882 C3orf24 0.43 5.96 0.31 6.17e-9 Alzheimer's disease; LIHC cis rs7647973 0.710 rs6446285 chr3:49626306 G/A cg03060546 chr3:49711283 APEH 0.56 5.95 0.31 6.77e-9 Menarche (age at onset); LIHC cis rs2933343 0.700 rs789233 chr3:128603150 G/T cg24203234 chr3:128598194 ACAD9 0.44 6.18 0.32 1.78e-9 IgG glycosylation; LIHC trans rs877282 0.533 rs10904565 chr10:819991 G/T cg22713356 chr15:30763199 NA 0.87 7.4 0.37 1.05e-12 Uric acid levels; LIHC cis rs2637266 1.000 rs12783273 chr10:78353221 T/C cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs835154 0.845 rs835155 chr5:14875868 A/G cg18064842 chr5:14874549 NA 0.43 8.82 0.43 5.92e-17 Blood metabolite levels; LIHC cis rs2836974 0.644 rs11088472 chr21:40699376 A/C cg11890956 chr21:40555474 PSMG1 -0.46 -7.45 -0.37 7.88e-13 Cognitive function; LIHC cis rs7772486 0.875 rs2328712 chr6:146344563 T/C cg23711669 chr6:146136114 FBXO30 0.6 10.54 0.5 1.12e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs12594515 1.000 rs8031128 chr15:45988528 C/G cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.71e-10 Waist circumference;Weight; LIHC cis rs17685 0.753 rs1637039 chr7:75693009 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.34 -0.32 7.24e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7843479 0.870 rs1809498 chr8:21836384 C/G cg17168535 chr8:21777572 XPO7 -0.37 -6.31 -0.32 8.7e-10 Mean corpuscular volume; LIHC cis rs2073300 0.609 rs3827086 chr20:23357331 C/T cg12062639 chr20:23401060 NAPB 1.08 14.28 0.61 1.26e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs867186 0.614 rs78260746 chr20:33426115 G/A cg08999081 chr20:33150536 PIGU 0.63 5.94 0.31 6.97e-9 Blood protein levels;Coronary artery disease;Hemostatic factors and hematological phenotypes;Factor VII levels;Protein C levels;D-dimer levels;Anticoagulant levels; LIHC trans rs9929218 0.954 rs12919719 chr16:68822341 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.56 -8.06 -0.4 1.32e-14 Colorectal cancer; LIHC cis rs4319547 0.695 rs1803290 chr12:122865029 T/C cg23029597 chr12:123009494 RSRC2 0.51 7.25 0.37 2.74e-12 Body mass index; LIHC cis rs9916302 0.706 rs6503521 chr17:37715551 A/C cg07936489 chr17:37558343 FBXL20 0.83 10.97 0.51 3.42e-24 Glomerular filtration rate (creatinine); LIHC cis rs6088590 0.735 rs6060003 chr20:33294945 T/C cg24642439 chr20:33292090 TP53INP2 0.58 8.33 0.41 2.02e-15 Coronary artery disease; LIHC cis rs10823500 0.636 rs7082396 chr10:71945511 C/A cg04118878 chr10:71993077 PPA1 0.56 5.75 0.3 2e-8 Blood protein levels; LIHC cis rs9902453 1.000 rs9902453 chr17:28349095 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.67 -11.21 -0.52 4.62e-25 Coffee consumption (cups per day); LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.08 0.55 3.2e-28 Prudent dietary pattern; LIHC cis rs9303401 0.659 rs12952325 chr17:56899371 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.04 0.58 7.65e-32 Cognitive test performance; LIHC cis rs8084351 0.501 rs7505807 chr18:50566190 C/G cg24270629 chr18:50823537 DCC 0.38 5.81 0.3 1.47e-8 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs17401966 0.867 rs6696056 chr1:10305992 C/A cg19773385 chr1:10388646 KIF1B -0.39 -7.16 -0.36 5.02e-12 Hepatocellular carcinoma; LIHC cis rs4589502 0.800 rs1498499 chr15:67202620 C/T cg12317470 chr15:67143691 NA -0.6 -7.33 -0.37 1.66e-12 Lung cancer (smoking interaction); LIHC cis rs8180040 1.000 rs7613282 chr3:47389409 C/T cg27129171 chr3:47204927 SETD2 -0.65 -10.98 -0.51 3.07e-24 Colorectal cancer; LIHC cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg09060608 chr5:178986726 RUFY1 0.37 5.76 0.3 1.91e-8 Lung cancer; LIHC cis rs1185460 0.546 rs2508948 chr11:118951642 A/T cg23280166 chr11:118938394 VPS11 -0.44 -5.81 -0.3 1.43e-8 Coronary artery disease; LIHC trans rs2243480 0.908 rs2460431 chr7:65622846 A/G cg10756647 chr7:56101905 PSPH -1.1 -13.4 -0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs875971 0.929 rs778682 chr7:65837934 A/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs700651 0.821 rs700666 chr2:198673544 G/A cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.42e-11 Intracranial aneurysm; LIHC cis rs7726839 0.540 rs7558 chr5:660491 C/T cg09021430 chr5:549028 NA -0.43 -8.6 -0.42 2.86e-16 Obesity-related traits; LIHC cis rs17345786 0.861 rs79181492 chr3:101216021 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.55 6.77 0.34 5.55e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs1008375 0.966 rs28441502 chr4:17598384 G/A cg02297831 chr4:17616191 MED28 0.48 7.2 0.36 3.78e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs35306767 0.855 rs12774985 chr10:904245 C/T cg20503657 chr10:835505 NA 1.33 14.33 0.61 8.06e-37 Eosinophil percentage of granulocytes; LIHC trans rs2727020 0.635 rs7124266 chr11:49280857 T/G cg15704280 chr7:45808275 SEPT13 0.77 11.59 0.53 2.09e-26 Coronary artery disease; LIHC cis rs9378688 1.000 rs3778568 chr6:2225680 C/T cg12303981 chr6:2244766 GMDS -0.5 -6.46 -0.33 3.62e-10 Caudate nucleus volume; LIHC cis rs8062405 1.000 rs62037365 chr16:28868962 C/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs611744 0.967 rs536860 chr8:109230722 A/C cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs1003719 0.751 rs56268364 chr21:38542765 C/T cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC trans rs116095464 0.558 rs10079760 chr5:230778 A/G cg00938859 chr5:1591904 SDHAP3 0.51 6.36 0.33 6.55e-10 Breast cancer; LIHC cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg08345575 chr16:4524283 NMRAL1;HMOX2 0.47 6.52 0.33 2.49e-10 Schizophrenia; LIHC cis rs6499255 0.951 rs9921045 chr16:69708698 C/T cg15192750 chr16:69999425 NA 0.44 6.74 0.34 6.73e-11 IgE levels; LIHC cis rs523522 0.962 rs10849759 chr12:120994488 T/A cg27279351 chr12:120934652 DYNLL1 0.67 12.08 0.55 3.21e-28 High light scatter reticulocyte count; LIHC cis rs6754311 0.550 rs1438307 chr2:136499166 A/C cg17750252 chr2:136567154 LCT -0.33 -5.95 -0.31 6.77e-9 Mosquito bite size; LIHC cis rs6754311 0.731 rs892715 chr2:136576577 T/C cg15123519 chr2:136567270 LCT 0.45 9.45 0.45 5.65e-19 Mosquito bite size; LIHC cis rs4718428 0.705 rs4718424 chr7:66376095 G/A cg12165864 chr7:66369176 NA -0.46 -6.76 -0.34 5.84e-11 Corneal structure; LIHC cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 9.33 0.45 1.39e-18 Platelet count; LIHC cis rs7116495 0.609 rs1791456 chr11:71594888 G/C cg10381502 chr11:71823885 C11orf51 0.89 7.5 0.38 5.47e-13 Severe influenza A (H1N1) infection; LIHC cis rs2574704 0.961 rs11712416 chr3:11649334 G/A cg15876825 chr3:11651881 VGLL4 -0.49 -8.11 -0.4 9.19e-15 Body mass index; LIHC cis rs7572733 0.534 rs700685 chr2:198715972 A/G cg00792783 chr2:198669748 PLCL1 0.49 7.32 0.37 1.76e-12 Dermatomyositis; LIHC cis rs244731 0.959 rs6872021 chr5:176610012 G/A cg17509989 chr5:176798049 RGS14 -0.67 -6.26 -0.32 1.14e-9 Urate levels in lean individuals; LIHC cis rs3099143 0.908 rs6495222 chr15:77180015 A/C cg21673338 chr15:77095150 SCAPER 0.51 7.94 0.39 2.93e-14 Recalcitrant atopic dermatitis; LIHC cis rs11864453 0.647 rs10492814 chr16:72126514 G/A cg01557791 chr16:72042693 DHODH -0.42 -6.97 -0.35 1.63e-11 Fibrinogen levels; LIHC cis rs2576037 0.526 rs607780 chr18:44417456 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.57 0.5 9e-23 Personality dimensions; LIHC cis rs5769765 1.000 rs768619 chr22:50287266 C/T cg26441486 chr22:50317300 CRELD2 0.35 6.33 0.32 7.65e-10 Schizophrenia; LIHC cis rs6060717 0.571 rs6060761 chr20:34612487 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -7.98 -0.4 2.25e-14 Hip circumference adjusted for BMI; LIHC cis rs7927592 0.913 rs12272917 chr11:68263370 T/C cg01657329 chr11:68192670 LRP5 -0.46 -5.97 -0.31 5.94e-9 Total body bone mineral density; LIHC cis rs9583531 0.600 rs6492306 chr13:111361693 G/A cg24331049 chr13:111365604 ING1 0.64 10.71 0.5 2.82e-23 Coronary artery disease; LIHC cis rs2072499 0.750 rs55675376 chr1:156165881 C/T cg25208724 chr1:156163844 SLC25A44 0.72 8.01 0.4 1.85e-14 Testicular germ cell tumor; LIHC cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg15691649 chr6:25882328 NA 0.78 11.18 0.52 6.31e-25 Blood metabolite levels; LIHC cis rs6466055 0.777 rs11765899 chr7:104923002 T/C cg04380332 chr7:105027541 SRPK2 0.37 6.86 0.35 3.2e-11 Schizophrenia; LIHC cis rs9916302 0.904 rs12450559 chr17:37694709 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.37 -0.59 4.35e-33 Glomerular filtration rate (creatinine); LIHC cis rs10949834 0.824 rs13236108 chr7:73521113 A/G cg07137043 chr7:73588983 EIF4H -0.6 -6.04 -0.31 3.92e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs798554 0.679 rs7784066 chr7:2819727 T/A cg13628971 chr7:2884303 GNA12 0.5 7.44 0.37 8.05e-13 Height; LIHC cis rs55665837 1.000 rs7121171 chr11:14446420 A/G cg19336497 chr11:14380999 RRAS2 -0.46 -8.59 -0.42 3.09e-16 Vitamin D levels; LIHC cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg23205692 chr1:25664452 TMEM50A 0.38 6.03 0.31 4.26e-9 Erythrocyte sedimentation rate; LIHC trans rs9747201 0.926 rs7222764 chr17:80062698 G/A cg07393940 chr7:158741817 NA -0.56 -6.61 -0.34 1.44e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs172166 0.637 rs1225592 chr6:28150242 G/A cg16479474 chr6:28041457 NA 0.35 5.77 0.3 1.79e-8 Cardiac Troponin-T levels; LIHC cis rs903552 0.932 rs9806551 chr15:102008206 C/T cg04789225 chr15:102009795 PCSK6 -0.43 -5.81 -0.3 1.39e-8 Diabetic kidney disease; LIHC cis rs7107174 1.000 rs2510046 chr11:77988817 T/C cg02023728 chr11:77925099 USP35 0.5 9.45 0.46 5.36e-19 Testicular germ cell tumor; LIHC cis rs798554 1.000 rs798544 chr7:2763102 A/G cg04166393 chr7:2884313 GNA12 -0.42 -5.84 -0.3 1.25e-8 Height; LIHC cis rs7959452 0.649 rs4761239 chr12:69776886 T/A cg20891283 chr12:69753455 YEATS4 0.88 18.05 0.7 1.26e-51 Blood protein levels; LIHC cis rs11166927 1.000 rs11166929 chr8:140801430 G/A cg16909799 chr8:140841666 TRAPPC9 0.5 7.97 0.4 2.39e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs7542091 0.669 rs11119357 chr1:210042382 C/T cg22029157 chr1:209979665 IRF6 0.36 6.12 0.31 2.53e-9 Monobrow; LIHC cis rs9393692 0.905 rs6931391 chr6:26279235 G/C cg00631329 chr6:26305371 NA -0.42 -7.18 -0.36 4.3e-12 Educational attainment; LIHC cis rs2380220 0.808 rs2613553 chr6:95916704 A/G cg15832292 chr6:96025679 MANEA -0.62 -7.02 -0.35 1.2e-11 Behavioural disinhibition (generation interaction); LIHC cis rs16828019 0.704 rs12024115 chr1:41534357 C/T cg03387723 chr1:41708464 SCMH1 -0.4 -6.45 -0.33 3.86e-10 Intelligence (multi-trait analysis); LIHC cis rs4843747 0.671 rs4075998 chr16:88106776 G/A cg06050784 chr16:88016603 BANP 0.36 6.56 0.33 1.96e-10 Menopause (age at onset); LIHC cis rs919433 0.963 rs12617117 chr2:198155170 T/A cg03934865 chr2:198174659 NA -0.61 -9.67 -0.46 1e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs4788570 0.547 rs6499538 chr16:71762285 A/C cg06353428 chr16:71660113 MARVELD3 1.33 13.55 0.59 8.83e-34 Intelligence (multi-trait analysis); LIHC cis rs908922 0.651 rs10888493 chr1:152503913 G/A cg20991723 chr1:152506922 NA 0.59 10.41 0.49 3.14e-22 Hair morphology; LIHC cis rs7512552 0.839 rs12040949 chr1:150447462 C/T cg15654264 chr1:150340011 RPRD2 0.68 11.04 0.51 1.9e-24 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC trans rs208520 0.661 rs6937856 chr6:66867468 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.76 -8.23 -0.41 3.95e-15 Exhaled nitric oxide output; LIHC cis rs17401966 0.931 rs12130563 chr1:10428452 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.73 -0.34 7.04e-11 Hepatocellular carcinoma; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg17512779 chr8:17104072 CNOT7;VPS37A 0.47 6.25 0.32 1.21e-9 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs2016586 0.929 rs5755921 chr22:36104730 A/G cg26342177 chr22:36113512 APOL5 0.36 5.85 0.3 1.13e-8 Body mass index; LIHC cis rs7116495 1.000 rs949325 chr11:71729656 A/G cg26138937 chr11:71823887 C11orf51 -0.83 -8.45 -0.42 8.57e-16 Severe influenza A (H1N1) infection; LIHC cis rs1538970 0.962 rs4660849 chr1:45819872 A/G cg05343316 chr1:45956843 TESK2 -0.6 -9.17 -0.44 4.52e-18 Platelet count; LIHC cis rs3820068 0.532 rs78917815 chr1:15920821 A/G cg17385448 chr1:15911702 AGMAT 0.36 6.23 0.32 1.34e-9 Systolic blood pressure; LIHC cis rs10193935 0.901 rs2374429 chr2:42677888 A/G cg27598129 chr2:42591480 NA -0.71 -10.59 -0.5 7.72e-23 Colonoscopy-negative controls vs population controls; LIHC trans rs7618501 0.633 rs4688690 chr3:50022292 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.48 0.46 4.54e-19 Intelligence (multi-trait analysis); LIHC cis rs1941023 0.503 rs11230288 chr11:60128968 G/A cg08716584 chr11:60157161 MS4A7 -0.35 -8.17 -0.4 5.84e-15 Congenital heart disease (maternal effect); LIHC cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg11764359 chr7:65958608 NA 0.69 9.32 0.45 1.46e-18 Calcium levels; LIHC cis rs36051895 0.623 rs3780383 chr9:5232409 G/C cg02405213 chr9:5042618 JAK2 -0.67 -10.12 -0.48 3.21e-21 Pediatric autoimmune diseases; LIHC cis rs7552404 0.690 rs7549863 chr1:76327923 T/C cg10523679 chr1:76189770 ACADM -0.55 -6.95 -0.35 1.82e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9470366 0.545 rs4713999 chr6:36633069 A/G cg00935119 chr6:36647544 CDKN1A 0.45 6.3 0.32 9.14e-10 QRS duration; LIHC cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg08280861 chr8:58055591 NA 0.51 6.19 0.32 1.7e-9 Developmental language disorder (linguistic errors); LIHC cis rs1475911 1.000 rs1475911 chr21:43513480 A/C cg19766460 chr21:43528205 UMODL1;C21orf128 0.78 11.7 0.53 8.13e-27 IgG glycosylation; LIHC trans rs6598955 0.671 rs10902732 chr1:26606174 A/C cg07461501 chr17:79650226 HGS;ARL16 -0.73 -8.29 -0.41 2.68e-15 Obesity-related traits; LIHC cis rs6952808 1.000 rs4721121 chr7:1892565 A/G cg14004847 chr7:1930337 MAD1L1 -0.41 -5.81 -0.3 1.42e-8 Bipolar disorder and schizophrenia; LIHC cis rs763121 0.925 rs9611008 chr22:39098787 T/C cg14440974 chr22:39074834 NA -0.37 -6.33 -0.32 7.88e-10 Menopause (age at onset); LIHC cis rs7107174 0.901 rs866901 chr11:77926309 C/T cg02023728 chr11:77925099 USP35 0.52 9.74 0.47 5.89e-20 Testicular germ cell tumor; LIHC cis rs2153535 0.546 rs9378559 chr6:8539058 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.36 0.41 1.64e-15 Motion sickness; LIHC cis rs11628318 0.564 rs8013957 chr14:103140254 C/T cg23461800 chr14:103021989 NA 0.39 5.82 0.3 1.32e-8 Platelet count; LIHC cis rs9388451 0.805 rs1028481 chr6:126106573 G/T cg05901451 chr6:126070800 HEY2 -0.73 -16.47 -0.67 2.69e-45 Brugada syndrome; LIHC cis rs10751667 0.961 rs6421967 chr11:983966 T/C ch.11.42038R chr11:967971 AP2A2 0.62 11.42 0.53 8.19e-26 Alzheimer's disease (late onset); LIHC cis rs7605378 0.528 rs1704191 chr2:200816393 C/A cg17644776 chr2:200775616 C2orf69 0.45 6.53 0.33 2.43e-10 Osteoporosis; LIHC trans rs950169 0.579 rs62027818 chr15:84661145 T/C cg24036039 chr1:3397125 ARHGEF16 0.4 6.56 0.33 1.99e-10 Schizophrenia; LIHC cis rs4474465 0.688 rs7108439 chr11:78277708 A/T cg02023728 chr11:77925099 USP35 -0.33 -5.85 -0.3 1.18e-8 Alzheimer's disease (survival time); LIHC cis rs9303401 0.659 rs12150264 chr17:56939927 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.51 0.56 7.65e-30 Cognitive test performance; LIHC cis rs4144743 0.938 rs55677902 chr17:45322572 G/T cg18085866 chr17:45331354 ITGB3 -0.58 -8.45 -0.42 8.45e-16 Body mass index; LIHC cis rs5753618 0.509 rs2079431 chr22:31564334 C/T cg22777020 chr22:31556080 RNF185 -0.54 -6.15 -0.32 2.16e-9 Colorectal cancer; LIHC cis rs920590 0.758 rs1826420 chr8:19664878 G/T cg03894339 chr8:19674705 INTS10 0.6 9.69 0.46 8.97e-20 Acute lymphoblastic leukemia (childhood); LIHC cis rs8177179 1.000 rs8177179 chr3:133463457 G/A cg24879335 chr3:133465180 TF 0.46 10.45 0.49 2.22e-22 Iron status biomarkers (transferrin levels); LIHC cis rs4948275 0.550 rs10994742 chr10:63132240 A/T cg03237606 chr10:63212265 TMEM26 0.32 7.3 0.37 2.05e-12 Night sleep phenotypes; LIHC cis rs9381040 0.655 rs9381029 chr6:41026453 G/C cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.74 -0.3 2.06e-8 Alzheimer's disease (late onset); LIHC cis rs8077889 0.917 rs9901676 chr17:41911818 T/C cg26893861 chr17:41843967 DUSP3 0.95 11.14 0.52 8.8e-25 Triglycerides; LIHC cis rs2066819 1.000 rs75265219 chr12:56640341 G/A cg26714650 chr12:56694279 CS -1.33 -12.81 -0.57 5.98e-31 Psoriasis vulgaris; LIHC cis rs10463316 0.894 rs3905511 chr5:150768204 G/A cg03212797 chr5:150827313 SLC36A1 -0.44 -6.68 -0.34 9.91e-11 Metabolite levels (Pyroglutamine); LIHC cis rs7258465 1.000 rs76194 chr19:18630580 T/G cg10790698 chr19:18539756 SSBP4 -0.34 -7.16 -0.36 4.92e-12 Breast cancer; LIHC cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg15556689 chr8:8085844 FLJ10661 0.44 6.99 0.35 1.48e-11 Systolic blood pressure; LIHC cis rs116095464 0.558 rs34629844 chr5:200829 A/G cg22857025 chr5:266934 NA -1.64 -16.58 -0.67 1.01e-45 Breast cancer; LIHC cis rs875971 1.000 rs4718343 chr7:65874288 T/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs2836950 0.545 rs2297256 chr21:40558421 C/T cg17971929 chr21:40555470 PSMG1 -0.39 -5.88 -0.3 9.54e-9 Menarche (age at onset); LIHC cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg22963979 chr7:1858916 MAD1L1 -0.42 -6.85 -0.35 3.47e-11 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01457418 chr15:75094936 CSK 0.37 6.09 0.31 3e-9 Pancreatic cancer; LIHC cis rs10540 1.000 rs12788729 chr11:502371 G/A cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.78e-15 Body mass index; LIHC cis rs3770081 1.000 rs56326127 chr2:86212201 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.78 -8.03 -0.4 1.62e-14 Facial emotion recognition (sad faces); LIHC cis rs6964587 0.967 rs10248102 chr7:91699779 G/A cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs10847980 0.590 rs1979237 chr12:123325895 C/T cg07706471 chr12:123319906 HIP1R 0.77 8.68 0.42 1.65e-16 Adiponectin levels; LIHC cis rs7312933 0.533 rs17551006 chr12:42848738 G/C cg17420585 chr12:42539391 GXYLT1 -0.35 -5.74 -0.3 2.05e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.55 8.36 0.41 1.65e-15 Height; LIHC cis rs3857067 0.804 rs6821438 chr4:95091911 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.55 -0.38 4.03e-13 QT interval; LIHC cis rs9910055 0.571 rs10208 chr17:42300278 C/T cg09913183 chr17:42254507 C17orf65;ASB16 0.55 8.13 0.4 7.71e-15 Total body bone mineral density; LIHC cis rs11931598 0.509 rs13140943 chr4:6977109 A/G cg26116260 chr4:7069785 GRPEL1 0.56 9.08 0.44 8.57e-18 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs7412746 0.611 rs111842513 chr1:150712926 G/A cg17724175 chr1:150552817 MCL1 0.49 10.01 0.48 7.43e-21 Melanoma; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02222454 chr3:141762828 NA 0.43 6.3 0.32 9.12e-10 Immature fraction of reticulocytes; LIHC cis rs7224737 0.956 rs7208907 chr17:40284783 C/T cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs11212260 0.573 rs12790708 chr11:107162153 G/A cg25435332 chr11:107328525 CWF19L2 0.64 6.06 0.31 3.66e-9 IgG glycosylation; LIHC cis rs6565681 0.883 rs4523980 chr17:78347664 A/G cg15383979 chr17:78362278 RNF213;LOC100294362 -0.52 -7.37 -0.37 1.33e-12 Moyamoya disease; LIHC cis rs16912285 0.688 rs12277966 chr11:24286633 G/A ch.11.24196551F chr11:24239977 NA 0.74 9.51 0.46 3.44e-19 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs2991971 0.716 rs7532573 chr1:45915892 A/T cg24296786 chr1:45957014 TESK2 -0.53 -8.16 -0.4 6.37e-15 High light scatter reticulocyte count; LIHC cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg13877915 chr19:58951672 ZNF132 0.6 9.72 0.47 6.9e-20 Uric acid clearance; LIHC cis rs7607369 0.679 rs6751527 chr2:219630965 C/G cg02985541 chr2:219472218 PLCD4 0.37 5.86 0.3 1.12e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs4650994 0.593 rs6676155 chr1:178508360 C/A cg05350800 chr1:178550844 NA -0.29 -6.31 -0.32 8.4e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs4650994 0.593 rs2761459 chr1:178551576 G/A cg05350800 chr1:178550844 NA -0.34 -7.56 -0.38 3.84e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs155076 1.000 rs12870992 chr13:21846019 A/G cg11317459 chr13:21872234 NA 1.13 13.02 0.58 9.23e-32 White matter hyperintensity burden; LIHC cis rs9640161 0.636 rs56190213 chr7:150025720 T/C cg17279839 chr7:150038598 RARRES2 0.58 11.74 0.54 5.48e-27 Blood protein levels;Circulating chemerin levels; LIHC cis rs11227306 0.934 rs7102454 chr11:65594820 C/T cg26695010 chr11:65641043 EFEMP2 0.42 5.75 0.3 1.94e-8 DNA methylation (variation); LIHC cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg18230493 chr5:56204884 C5orf35 -0.43 -6.03 -0.31 4.26e-9 Initial pursuit acceleration; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg26574964 chr11:117049906 SIDT2 0.47 6.62 0.34 1.38e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.966 rs11707895 chr3:47574937 G/A cg16586182 chr3:47516702 SCAP 0.44 7.48 0.37 6.32e-13 Colorectal cancer; LIHC cis rs921968 0.643 rs484085 chr2:219396684 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.68 0.42 1.62e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs4586057 0.533 rs6583737 chr10:92620789 A/G cg14313238 chr10:92632228 RPP30 0.36 5.99 0.31 5.4e-9 Economic and political preferences (time); LIHC cis rs7208859 0.623 rs55961983 chr17:29119286 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1494950 1.000 rs2604582 chr4:15061142 A/G cg12377275 chr4:15005593 CPEB2 -0.83 -7.22 -0.36 3.42e-12 Political ideology; LIHC cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.2e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs637571 0.522 rs556643 chr11:65733289 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.43 6.77 0.34 5.69e-11 Eosinophil percentage of white cells; LIHC cis rs4819052 1.000 rs733739 chr21:46666210 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.71 9.51 0.46 3.61e-19 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9534288 0.699 rs2296642 chr13:46656669 A/G cg15192986 chr13:46630673 CPB2 -0.44 -6.35 -0.32 6.91e-10 Blood protein levels; LIHC cis rs10751667 0.560 rs7924794 chr11:962745 A/T cg06064525 chr11:970664 AP2A2 -0.57 -15.08 -0.63 9.46e-40 Alzheimer's disease (late onset); LIHC cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg11644478 chr21:40555479 PSMG1 0.47 7.27 0.37 2.54e-12 Cognitive function; LIHC cis rs9814567 1.000 rs9819532 chr3:134288644 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg12310025 chr6:25882481 NA 0.94 12.73 0.57 1.15e-30 Blood metabolite levels; LIHC cis rs9596863 1.000 rs9596859 chr13:54431200 T/A ch.13.53330881F chr13:54432880 NA 0.46 6.2 0.32 1.66e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs1580019 0.665 rs34147895 chr7:32531796 G/C cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.83 0.43 5.36e-17 Cognitive ability; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15581235 chr15:41708917 RTF1 0.48 6.4 0.33 5.18e-10 Lung function (FEV1/FVC); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10981275 chr2:3381760 TSSC1 0.49 6.99 0.35 1.47e-11 Lung function (FEV1/FVC); LIHC cis rs6429082 0.818 rs291341 chr1:235663174 G/T cg26050004 chr1:235667680 B3GALNT2 0.5 7.67 0.38 1.86e-13 Adiposity; LIHC cis rs9309473 1.000 rs13432605 chr2:73810981 C/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.5 -0.33 2.86e-10 Metabolite levels; LIHC cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg06238570 chr21:40685208 BRWD1 0.58 6.89 0.35 2.72e-11 Cognitive function; LIHC cis rs3736485 0.868 rs1531155 chr15:51932133 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -5.95 -0.31 6.66e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8020095 0.571 rs8009087 chr14:67564210 C/T cg03487553 chr14:67822707 ATP6V1D 0.33 5.75 0.3 2.02e-8 Depression (quantitative trait); LIHC cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg27094323 chr7:1216898 NA -0.4 -5.83 -0.3 1.28e-8 Longevity;Endometriosis; LIHC cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg02290350 chr8:58132656 NA 0.47 9.99 0.48 8.93e-21 Developmental language disorder (linguistic errors); LIHC cis rs2976388 0.609 rs2717550 chr8:143787808 T/A cg06565975 chr8:143823917 SLURP1 0.33 6.41 0.33 4.77e-10 Urinary tract infection frequency; LIHC cis rs7772486 0.727 rs10223508 chr6:146285205 C/T cg23711669 chr6:146136114 FBXO30 -0.61 -10.6 -0.5 6.83e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs8141529 0.702 rs5762870 chr22:29261159 C/T cg15103426 chr22:29168792 CCDC117 0.59 9.92 0.47 1.51e-20 Lymphocyte counts; LIHC cis rs4820539 1.000 rs4822357 chr22:23473231 A/G cg14186256 chr22:23484241 RTDR1 0.87 17.26 0.68 1.96e-48 Bone mineral density; LIHC trans rs875971 0.895 rs3857684 chr7:65938158 G/C cg10756647 chr7:56101905 PSPH 0.44 6.46 0.33 3.59e-10 Aortic root size; LIHC cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg20607798 chr8:58055168 NA -0.61 -7.58 -0.38 3.28e-13 Developmental language disorder (linguistic errors); LIHC cis rs6665290 0.904 rs11587443 chr1:227187896 T/C cg10327440 chr1:227177885 CDC42BPA -1.19 -31.38 -0.86 1.02e-102 Myeloid white cell count; LIHC cis rs3736485 0.934 rs28695624 chr15:51874928 A/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs597539 0.652 rs557625 chr11:68634722 G/A cg04772025 chr11:68637568 NA 0.46 6.24 0.32 1.33e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC trans rs7246657 0.943 rs7255972 chr19:37933841 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs7945705 0.902 rs10743093 chr11:8869129 A/G cg12365402 chr11:9010492 NRIP3 0.28 6.89 0.35 2.7e-11 Hemoglobin concentration; LIHC cis rs10876993 0.680 rs2277322 chr12:58009202 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.43 5.91 0.3 8.38e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs711245 0.748 rs2276671 chr2:36771701 C/A cg10546459 chr2:36825355 FEZ2 0.51 6.23 0.32 1.4e-9 Height; LIHC cis rs9916302 0.904 rs585961 chr17:37444036 G/A cg03013999 chr17:37608204 MED1 -0.36 -6.04 -0.31 3.93e-9 Glomerular filtration rate (creatinine); LIHC cis rs6088590 1.000 rs1998028 chr20:33344595 A/T cg08999081 chr20:33150536 PIGU 0.37 5.77 0.3 1.78e-8 Coronary artery disease; LIHC cis rs11039131 0.787 rs326217 chr11:47303275 T/C cg20135002 chr11:47629003 NA -0.36 -5.71 -0.3 2.43e-8 Schizophrenia; LIHC cis rs2153535 0.580 rs1414348 chr6:8471940 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.74 0.43 1.05e-16 Motion sickness; LIHC cis rs7312933 0.558 rs11181501 chr12:42822671 G/A cg01256987 chr12:42539512 GXYLT1 -0.36 -5.91 -0.3 8.32e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg03517284 chr6:25882590 NA -0.59 -7.26 -0.37 2.71e-12 Intelligence (multi-trait analysis); LIHC cis rs7903847 0.596 rs7922512 chr10:99155685 C/A cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.53e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09561351 chr12:42876655 PRICKLE1 0.49 7.23 0.36 3.15e-12 Pancreatic cancer; LIHC cis rs2574704 1.000 rs2447614 chr3:11664032 A/T cg15876825 chr3:11651881 VGLL4 -0.51 -8.34 -0.41 1.87e-15 Body mass index; LIHC cis rs1046896 0.553 rs72634343 chr17:80827392 T/C cg02711726 chr17:80685570 FN3KRP -0.43 -7.93 -0.39 3.09e-14 Glycated hemoglobin levels; LIHC cis rs8017423 0.935 rs4643251 chr14:90669256 C/T cg14092571 chr14:90743983 NA 0.39 6.17 0.32 1.97e-9 Mortality in heart failure; LIHC cis rs79149102 0.579 rs8033125 chr15:75374970 G/C cg15902774 chr15:75289873 SCAMP5 0.4 5.94 0.31 6.89e-9 Lung cancer; LIHC cis rs858239 0.600 rs7790157 chr7:23126998 G/A cg23682824 chr7:23144976 KLHL7 0.46 6.95 0.35 1.89e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg13047869 chr3:10149882 C3orf24 0.5 6.08 0.31 3.23e-9 Alzheimer's disease; LIHC cis rs2153535 0.623 rs2152346 chr6:8454652 A/G cg21535247 chr6:8435926 SLC35B3 0.64 8.57 0.42 3.5e-16 Motion sickness; LIHC cis rs13108904 0.901 rs12641735 chr4:1304434 G/C cg19318889 chr4:1322082 MAEA 0.54 9.14 0.44 5.66e-18 Obesity-related traits; LIHC cis rs1419980 0.586 rs10845548 chr12:7777657 T/A cg14906510 chr12:7781169 NA -0.46 -7.23 -0.36 3.17e-12 HDL cholesterol levels; LIHC cis rs875971 0.964 rs778721 chr7:65845397 C/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs35306767 0.903 rs12250936 chr10:870109 C/T cg20503657 chr10:835505 NA 1.03 11.76 0.54 4.63e-27 Eosinophil percentage of granulocytes; LIHC cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.02 -0.35 1.22e-11 Diabetic kidney disease; LIHC cis rs9303401 0.703 rs8077052 chr17:57208921 T/G cg10487724 chr17:56770010 TEX14;RAD51C 0.42 6.26 0.32 1.12e-9 Cognitive test performance; LIHC cis rs10857712 0.904 rs7083614 chr10:135226236 G/A cg15472797 chr10:135243109 NA -0.39 -5.77 -0.3 1.79e-8 Systemic lupus erythematosus; LIHC cis rs11971779 0.584 rs17613864 chr7:139095587 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08409687 chr2:201936025 NDUFB3;FAM126B 0.42 6.21 0.32 1.58e-9 Cognitive function; LIHC cis rs11628318 0.660 rs35258120 chr14:103058769 G/A cg01864069 chr14:103024347 NA -0.46 -7.17 -0.36 4.62e-12 Platelet count; LIHC cis rs1475911 1.000 rs34421316 chr21:43513989 C/T cg19766460 chr21:43528205 UMODL1;C21orf128 0.77 11.25 0.52 3.51e-25 IgG glycosylation; LIHC trans rs916888 0.821 rs70600 chr17:44860021 C/T cg13957321 chr17:43675089 NA 0.5 7.9 0.39 3.98e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg21747090 chr2:27597821 SNX17 0.44 6.53 0.33 2.42e-10 Total body bone mineral density; LIHC cis rs9916302 0.904 rs600010 chr17:37433517 T/C cg03013999 chr17:37608204 MED1 0.36 5.97 0.31 5.89e-9 Glomerular filtration rate (creatinine); LIHC cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.47 6.37 0.33 6.07e-10 Schizophrenia; LIHC cis rs17685 0.753 rs4728550 chr7:75670988 C/A cg01364799 chr7:75623366 TMEM120A 0.52 7.83 0.39 6.35e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4294134 0.832 rs35061496 chr7:135254269 T/C cg20392616 chr7:135392013 SLC13A4 0.37 5.93 0.31 7.31e-9 Paget's disease; LIHC trans rs6934970 1.000 rs12203507 chr6:113095654 T/G cg09308777 chr6:169852575 NA 0.57 6.15 0.32 2.22e-9 Bipolar disorder (body mass index interaction); LIHC cis rs5167 0.506 rs35193317 chr19:45470344 C/T cg13119609 chr19:45449297 APOC2 -0.23 -6.79 -0.34 4.89e-11 Blood protein levels; LIHC cis rs919433 0.963 rs1896854 chr2:198147776 G/T cg03934865 chr2:198174659 NA -0.6 -9.87 -0.47 2.23e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7191700 0.644 rs918738 chr16:11439679 C/G cg00044050 chr16:11439710 C16orf75 -0.53 -7.74 -0.39 1.14e-13 Multiple sclerosis; LIHC cis rs1816752 0.905 rs9511260 chr13:25011176 T/C cg22771759 chr13:24902376 NA 0.32 6.75 0.34 6.32e-11 Obesity-related traits; LIHC cis rs8180040 0.676 rs66564457 chr3:47020072 G/A cg02527881 chr3:46936655 PTH1R -0.36 -7.16 -0.36 4.98e-12 Colorectal cancer; LIHC cis rs3796619 1.000 rs4974601 chr4:1095410 G/A cg27284194 chr4:1044797 NA 0.64 10.73 0.5 2.46e-23 Recombination rate (males); LIHC cis rs2180341 0.960 rs3756996 chr6:127664258 G/C cg27446573 chr6:127587934 RNF146 1.02 15.68 0.65 3.78e-42 Breast cancer; LIHC cis rs2016586 0.863 rs5755931 chr22:36120323 A/G cg26342177 chr22:36113512 APOL5 -0.37 -6.34 -0.32 7.31e-10 Body mass index; LIHC cis rs644799 1.000 rs505220 chr11:95563228 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.36 0.68 7.36e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs2073499 0.872 rs41291724 chr3:50294066 C/G cg21659725 chr3:3221576 CRBN 0.64 6.1 0.31 2.8e-9 Schizophrenia; LIHC cis rs637571 0.528 rs11602769 chr11:65594139 T/C cg26695010 chr11:65641043 EFEMP2 0.47 6.65 0.34 1.17e-10 Eosinophil percentage of white cells; LIHC cis rs9303401 0.659 rs17741087 chr17:56550300 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.87 11.39 0.52 1.05e-25 Cognitive test performance; LIHC cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.71 -0.57 1.46e-30 Alzheimer's disease; LIHC cis rs711245 0.670 rs7560321 chr2:36822318 C/G cg09467607 chr2:36825704 FEZ2 -0.43 -7.08 -0.36 8.22e-12 Height; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg01171360 chr6:293285 DUSP22 -0.44 -6.38 -0.33 5.83e-10 Menopause (age at onset); LIHC cis rs7208859 0.623 rs11652358 chr17:29205480 T/C cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7408868 0.908 rs10416865 chr19:15277601 T/C cg14696996 chr19:15285081 NOTCH3 0.53 7.11 0.36 6.93e-12 Pulse pressure; LIHC cis rs2153535 0.580 rs2327058 chr6:8447018 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.04 0.4 1.5e-14 Motion sickness; LIHC cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg12463550 chr7:65579703 CRCP 0.67 7.18 0.36 4.48e-12 Diabetic kidney disease; LIHC cis rs2559856 0.967 rs2695290 chr12:102087844 A/G cg12924262 chr12:102091054 CHPT1 -0.49 -7.94 -0.39 2.99e-14 Blood protein levels; LIHC cis rs10861342 0.892 rs12227605 chr12:105501100 G/A cg23923672 chr12:105501055 KIAA1033 0.69 8.48 0.42 7e-16 IgG glycosylation; LIHC cis rs6138458 1.000 rs6114980 chr20:24974288 A/G cg26195577 chr20:24973756 C20orf3 1.2 16.23 0.66 2.61e-44 Blood protein levels; LIHC cis rs1005277 0.579 rs1740742 chr10:38518860 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg09323728 chr8:95962352 TP53INP1 -0.3 -5.96 -0.31 6.25e-9 Type 2 diabetes; LIHC cis rs1775715 0.707 rs2808073 chr10:32179275 A/G cg14930904 chr10:32216787 ARHGAP12 0.36 6.43 0.33 4.18e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs614226 0.516 rs1794748 chr12:120953758 A/G cg27489772 chr12:121021490 NA 0.51 5.72 0.3 2.33e-8 Type 1 diabetes nephropathy; LIHC cis rs6088580 0.542 rs6059882 chr20:33090167 T/C cg08999081 chr20:33150536 PIGU 0.67 13.44 0.59 2.3e-33 Glomerular filtration rate (creatinine); LIHC cis rs9814567 1.000 rs62269547 chr3:134214042 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.13 -0.55 2.01e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg18357526 chr6:26021779 HIST1H4A 0.39 5.75 0.3 2.01e-8 Height; LIHC cis rs77633900 0.772 rs2957611 chr15:76704878 C/T cg21673338 chr15:77095150 SCAPER -0.52 -5.77 -0.3 1.78e-8 Non-glioblastoma glioma;Glioma; LIHC cis rs9733 0.519 rs11807450 chr1:150677719 C/T cg18016565 chr1:150552671 MCL1 0.59 11.43 0.53 7.69e-26 Tonsillectomy; LIHC cis rs9733 0.596 rs12077833 chr1:150674333 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.06e-9 Tonsillectomy; LIHC cis rs7633770 0.786 rs6808214 chr3:46682746 T/C cg11219411 chr3:46661640 NA 0.45 8.02 0.4 1.73e-14 Coronary artery disease; LIHC cis rs12908161 1.000 rs12903134 chr15:85337699 T/A cg17507749 chr15:85114479 UBE2QP1 0.63 7.18 0.36 4.38e-12 Schizophrenia; LIHC trans rs916888 0.647 rs199523 chr17:44848517 C/A cg22968622 chr17:43663579 NA -0.49 -7.01 -0.35 1.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg22442454 chr1:209979470 IRF6 0.38 5.74 0.3 2.08e-8 Cleft lip with or without cleft palate; LIHC cis rs28453840 1 rs28453840 chr2:136522941 G/A cg07305463 chr2:136567211 LCT 0.41 7.73 0.39 1.24e-13 Cholesterol, total; LIHC cis rs769267 0.930 rs3794990 chr19:19610030 A/G cg03709012 chr19:19516395 GATAD2A 1.01 18.36 0.7 6.84e-53 Tonsillectomy; LIHC cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg04944784 chr2:26401820 FAM59B -0.73 -9.24 -0.45 2.78e-18 Gut microbiome composition (summer); LIHC cis rs8062405 1.000 rs55991577 chr16:28843025 C/T cg00204512 chr16:28754710 NA 0.34 6.37 0.33 6.01e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs1005277 0.579 rs2103938 chr10:38493998 T/G cg17830980 chr10:43048298 ZNF37B -0.5 -9.56 -0.46 2.41e-19 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.47 0.37 6.74e-13 Prudent dietary pattern; LIHC cis rs910316 0.967 rs11624893 chr14:75660124 A/G cg11812906 chr14:75593930 NEK9 -0.7 -13.32 -0.58 6.8e-33 Height; LIHC cis rs11673344 0.704 rs826290 chr19:37428445 C/T cg27390819 chr19:37464633 NA -0.51 -6.08 -0.31 3.28e-9 Obesity-related traits; LIHC trans rs17685 0.535 rs41296542 chr7:75600008 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 7.61 0.38 2.69e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6442522 0.678 rs11128745 chr3:15498261 T/C cg16303742 chr3:15540471 COLQ 0.44 7.35 0.37 1.48e-12 Uric acid levels; LIHC cis rs244293 0.965 rs244300 chr17:53239240 T/A cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.2 -0.32 1.6e-9 Menarche (age at onset); LIHC cis rs11719291 0.504 rs34571182 chr3:49209057 T/A cg07636037 chr3:49044803 WDR6 -0.78 -7.85 -0.39 5.41e-14 Cognitive function; LIHC cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg18305652 chr10:134549665 INPP5A 0.45 6.42 0.33 4.45e-10 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg11764359 chr7:65958608 NA -0.59 -6.21 -0.32 1.54e-9 Diabetic kidney disease; LIHC cis rs12478296 1.000 rs6739247 chr2:243039189 C/A cg06360820 chr2:242988706 NA -0.86 -12.14 -0.55 1.87e-28 Obesity-related traits; LIHC cis rs9393692 0.905 rs989134 chr6:26336224 A/C cg00631329 chr6:26305371 NA -0.43 -7.36 -0.37 1.41e-12 Educational attainment; LIHC cis rs1552244 0.572 rs3843008 chr3:10173742 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.74 -7.5 -0.38 5.5e-13 Alzheimer's disease; LIHC cis rs7216064 1.000 rs9912084 chr17:65868035 A/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs1577917 1.000 rs12207305 chr6:86723502 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.42 -6.9 -0.35 2.54e-11 Response to antipsychotic treatment; LIHC cis rs8083850 0.635 rs4450475 chr18:50855622 C/T cg24270629 chr18:50823537 DCC -0.58 -8.83 -0.43 5.65e-17 Intelligence (multi-trait analysis); LIHC cis rs921968 0.541 rs55996799 chr2:219558193 C/G cg02176678 chr2:219576539 TTLL4 -0.54 -7.03 -0.36 1.16e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg06238570 chr21:40685208 BRWD1 -0.4 -6.38 -0.33 5.74e-10 Menarche (age at onset); LIHC cis rs5769707 0.846 rs5770610 chr22:50036897 A/C cg01652190 chr22:50026171 C22orf34 -0.3 -6.88 -0.35 2.89e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs7615952 0.932 rs13321217 chr3:125631771 G/A cg05084668 chr3:125655381 ALG1L -0.59 -8.8 -0.43 6.92e-17 Blood pressure (smoking interaction); LIHC trans rs6952808 0.771 rs10275045 chr7:1920826 C/T cg04565464 chr8:145669602 NFKBIL2 0.4 6.42 0.33 4.68e-10 Bipolar disorder and schizophrenia; LIHC cis rs11958404 0.932 rs72816584 chr5:157433190 G/A cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg11060661 chr22:24314208 DDT;DDTL 0.64 10.82 0.5 1.19e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1401999 0.966 rs2037379 chr3:183650330 T/C cg01324343 chr3:183735012 ABCC5 0.73 11.81 0.54 3.17e-27 Anterior chamber depth; LIHC cis rs9303401 0.614 rs66480139 chr17:57101538 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.9 12.41 0.56 1.91e-29 Cognitive test performance; LIHC cis rs2228479 0.850 rs62052711 chr16:89855100 C/A cg19635926 chr16:89946313 TCF25 0.53 6.5 0.33 2.8e-10 Skin colour saturation; LIHC cis rs2346177 0.542 rs718849 chr2:46698116 G/A cg02822958 chr2:46747628 ATP6V1E2 0.51 7.56 0.38 3.86e-13 HDL cholesterol; LIHC cis rs6456156 0.586 rs9457261 chr6:167467679 A/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.7 -0.43 1.45e-16 Primary biliary cholangitis; LIHC trans rs17439560 0.510 rs10153002 chr15:37433594 A/C cg06425556 chr20:33413664 NCOA6 0.77 6.08 0.31 3.24e-9 Response to amphetamines; LIHC cis rs7116495 1.000 rs59343384 chr11:71828038 G/C cg26138937 chr11:71823887 C11orf51 0.71 7.3 0.37 2.08e-12 Severe influenza A (H1N1) infection; LIHC cis rs2073300 1.000 rs17830565 chr20:23444805 G/A cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6061231 0.630 rs62196294 chr20:60973432 T/G cg24112000 chr20:60950667 NA -0.61 -9.82 -0.47 3.37e-20 Colorectal cancer; LIHC cis rs4699052 0.826 rs17033498 chr4:104179961 C/G cg16532752 chr4:104119610 CENPE -0.41 -6.42 -0.33 4.47e-10 Testicular germ cell tumor; LIHC cis rs1986734 0.619 rs13106413 chr4:77418698 G/T cg24201034 chr4:77507246 SHROOM3 -0.38 -6.14 -0.31 2.34e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs7927771 0.524 rs7118747 chr11:47889545 C/T cg20307385 chr11:47447363 PSMC3 -0.65 -9.77 -0.47 4.92e-20 Subjective well-being; LIHC cis rs9473924 0.542 rs9473922 chr6:50831792 C/T cg14470998 chr6:50812995 TFAP2B 0.92 10.58 0.5 7.79e-23 Body mass index; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg20471045 chr19:49568214 NTF4 -0.42 -6.2 -0.32 1.64e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg11301795 chr4:187892539 NA -0.26 -6.99 -0.35 1.44e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg24846343 chr22:24311635 DDTL 0.72 14.59 0.62 8.06e-38 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8060686 0.516 rs7197756 chr16:68275516 A/C cg05110241 chr16:68378359 PRMT7 -0.53 -6.35 -0.32 6.87e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs10876993 0.890 rs115106209 chr12:58059331 G/A cg18357645 chr12:58087776 OS9 0.51 8.42 0.41 1.06e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs1538970 0.924 rs7531253 chr1:45890183 T/C cg24296786 chr1:45957014 TESK2 -0.5 -7.21 -0.36 3.53e-12 Platelet count; LIHC cis rs589448 0.902 rs315138 chr12:69764850 A/T cg20891283 chr12:69753455 YEATS4 0.95 22.46 0.77 2.7e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs523522 0.962 rs651627 chr12:121009198 C/T cg12219531 chr12:120966889 COQ5 0.67 13.15 0.58 3.15e-32 High light scatter reticulocyte count; LIHC cis rs7312774 0.881 rs79048355 chr12:107311169 G/T cg16260113 chr12:107380972 MTERFD3 0.77 10.03 0.48 6.34e-21 Severe influenza A (H1N1) infection; LIHC cis rs2777491 1.000 rs1757455 chr15:41761332 G/T cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.27 -0.45 2.2e-18 Ulcerative colitis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25617285 chr1:211431773 RCOR3 0.37 6.52 0.33 2.53e-10 Cognitive function; LIHC cis rs2991971 0.869 rs2453404 chr1:46014735 A/G cg03146154 chr1:46216737 IPP -0.38 -5.85 -0.3 1.13e-8 High light scatter reticulocyte count; LIHC cis rs12188164 0.543 rs7728027 chr5:459943 T/C cg26072250 chr5:443457 EXOC3;C5orf55 0.47 7.07 0.36 8.74e-12 Cystic fibrosis severity; LIHC cis rs1865760 0.566 rs2032449 chr6:26026599 G/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.84 0.3 1.21e-8 Height; LIHC cis rs2637266 0.655 rs2588335 chr10:78510229 C/G cg18941641 chr10:78392320 NA 0.28 6.07 0.31 3.34e-9 Pulmonary function; LIHC cis rs1997103 0.871 rs1997100 chr7:55399656 C/G cg17469321 chr7:55412551 NA 0.48 7.1 0.36 7.37e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs12142240 0.698 rs66911505 chr1:46823298 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs10744422 0.800 rs839363 chr12:123276924 C/T cg25930673 chr12:123319894 HIP1R -0.84 -10.39 -0.49 3.64e-22 Schizophrenia; LIHC trans rs11039798 0.588 rs12284168 chr11:48555627 C/T cg15704280 chr7:45808275 SEPT13 0.58 6.44 0.33 4.03e-10 Axial length; LIHC cis rs2153535 0.580 rs6902001 chr6:8477055 T/G cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs7000551 0.663 rs11778831 chr8:22335088 C/T cg12081754 chr8:22256438 SLC39A14 0.51 8.48 0.42 6.88e-16 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs9556958 0.708 rs4772092 chr13:99166614 A/G cg20750642 chr13:99100586 FARP1 0.34 6.14 0.32 2.3e-9 Educational attainment (years of education); LIHC cis rs9457247 1.000 rs415890 chr6:167406633 C/G cg12798992 chr6:167411361 FGFR1OP -0.58 -9.5 -0.46 3.93e-19 Crohn's disease; LIHC cis rs1577917 0.958 rs4707223 chr6:86509802 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.13 -0.4 7.9e-15 Response to antipsychotic treatment; LIHC cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg27170947 chr2:26402098 FAM59B -0.72 -8.67 -0.42 1.7e-16 Gut microbiome composition (summer); LIHC cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg12463550 chr7:65579703 CRCP -0.66 -6.96 -0.35 1.78e-11 Diabetic kidney disease; LIHC trans rs1005277 0.522 rs9417256 chr10:37976990 A/G cg27523141 chr10:43048294 ZNF37B 0.38 6.58 0.34 1.77e-10 Extrinsic epigenetic age acceleration; LIHC cis rs6952808 0.500 rs3778996 chr7:2177190 G/A cg20295408 chr7:1910781 MAD1L1 -0.39 -5.73 -0.3 2.24e-8 Bipolar disorder and schizophrenia; LIHC cis rs2334880 0.713 rs4788828 chr16:71724090 C/A cg06353428 chr16:71660113 MARVELD3 1.39 15.34 0.64 8.91e-41 Malaria; LIHC trans rs1005277 0.579 rs1780115 chr10:38524773 C/T cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC trans rs8002861 0.869 rs7989857 chr13:44464090 C/T cg17145862 chr1:211918768 LPGAT1 0.67 13.29 0.58 9.1e-33 Leprosy; LIHC cis rs8077889 0.917 rs58283314 chr17:41905963 T/G cg26893861 chr17:41843967 DUSP3 0.93 10.72 0.5 2.51e-23 Triglycerides; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20095036 chr4:153456176 FBXW7 0.47 6.06 0.31 3.59e-9 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg18252515 chr7:66147081 NA 1.27 16.71 0.67 2.89e-46 Diabetic kidney disease; LIHC cis rs965469 1.000 rs6051702 chr20:3251924 A/C cg25506879 chr20:3388711 C20orf194 -0.59 -6.84 -0.35 3.75e-11 IFN-related cytopenia; LIHC cis rs7223966 1.000 rs16947042 chr17:61766457 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.83e-12 Hip circumference adjusted for BMI;Body mass index; LIHC trans rs1814175 0.645 rs11040535 chr11:49808669 C/T cg03929089 chr4:120376271 NA -0.84 -15.87 -0.65 6.88e-43 Height; LIHC cis rs9303280 0.806 rs35569035 chr17:38035624 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.77 0.3 1.76e-8 Self-reported allergy; LIHC cis rs35306767 0.903 rs7914758 chr10:891702 T/C cg26597838 chr10:835615 NA 1.49 17.34 0.68 8.86e-49 Eosinophil percentage of granulocytes; LIHC cis rs12594515 1.000 rs8038320 chr15:45990267 G/C cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.75e-19 Waist circumference;Weight; LIHC cis rs7762018 1.000 rs17860606 chr6:170099561 G/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.5 5.74 0.3 2.04e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs77633900 0.502 rs116917406 chr15:76922940 T/C cg21673338 chr15:77095150 SCAPER -0.51 -6.97 -0.35 1.61e-11 Non-glioblastoma glioma;Glioma; LIHC cis rs4903214 0.895 rs12433272 chr14:74715250 C/T cg11132536 chr14:74711944 VSX2 -0.23 -5.77 -0.3 1.76e-8 Inflammatory bowel disease; LIHC cis rs3806843 0.966 rs12659129 chr5:140147248 T/C cg26395211 chr5:140044315 WDR55 -0.4 -5.97 -0.31 5.79e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs34779708 0.931 rs13376871 chr10:35369056 A/G cg03585969 chr10:35415529 CREM 0.85 12.94 0.57 1.88e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.15 0.55 1.69e-28 Height; LIHC cis rs7312933 0.932 rs10880220 chr12:42383046 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.44 6.34 0.32 7.34e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs4555082 0.874 rs2816613 chr14:105726367 C/T cg13114125 chr14:105738426 BRF1 -0.72 -9.35 -0.45 1.21e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs17685 0.672 rs10952841 chr7:75778626 A/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7927771 1.000 rs10838748 chr11:47716381 T/G cg20135002 chr11:47629003 NA -0.55 -9.52 -0.46 3.37e-19 Subjective well-being; LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg13395646 chr4:1353034 KIAA1530 -0.41 -5.87 -0.3 1.05e-8 Longevity; LIHC cis rs453301 0.506 rs686189 chr8:8623637 A/G cg06636001 chr8:8085503 FLJ10661 -0.41 -6.77 -0.34 5.55e-11 Joint mobility (Beighton score); LIHC cis rs262150 1.000 rs262154 chr7:158773936 G/A cg19418458 chr7:158789849 NA -0.4 -6.74 -0.34 6.5500000000000006e-11 Facial morphology (factor 20); LIHC cis rs2439831 1.000 rs9920763 chr15:43760508 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.64 7.33 0.37 1.62e-12 Lung cancer in ever smokers; LIHC cis rs7191439 0.674 rs4782429 chr16:88792097 A/G cg02389323 chr16:88786976 FAM38A 0.84 8.38 0.41 1.38e-15 Plateletcrit; LIHC cis rs10876993 0.928 rs10877001 chr12:58083077 T/C cg04478727 chr12:58166393 METTL1;FAM119B 0.43 6.06 0.31 3.55e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs62458065 0.850 rs6462362 chr7:32464733 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.58 -5.72 -0.3 2.33e-8 Metabolite levels (HVA/MHPG ratio); LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg20279561 chr13:113356724 ATP11A -0.4 -6.58 -0.34 1.8e-10 Pain; LIHC cis rs6942756 0.806 rs2718115 chr7:128871532 A/G cg02491457 chr7:128862824 NA 0.64 10.3 0.49 7.46e-22 White matter hyperintensity burden; LIHC cis rs35110281 0.776 rs229357 chr21:44982717 T/C cg01579765 chr21:45077557 HSF2BP -0.37 -6.87 -0.35 2.99e-11 Mean corpuscular volume; LIHC cis rs9916302 0.904 rs8076494 chr17:37516722 A/G cg07936489 chr17:37558343 FBXL20 0.75 11.69 0.53 8.86e-27 Glomerular filtration rate (creatinine); LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg01715370 chr17:40169196 DNAJC7;NKIRAS2 0.66 6.84 0.35 3.71e-11 Mean platelet volume; LIHC cis rs7619427 0.908 rs17076344 chr3:44079670 C/T cg24966902 chr3:44043705 NA 0.49 6.87 0.35 3.09e-11 Schizophrenia; LIHC cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg00656387 chr3:40428638 ENTPD3 0.49 8.31 0.41 2.35e-15 Renal cell carcinoma; LIHC trans rs8117834 0.574 rs6086330 chr20:8082272 T/G cg00593689 chr4:53575888 NA 0.38 6.5 0.33 2.77e-10 Chronic kidney disease; LIHC cis rs769267 0.896 rs7250893 chr19:19625547 A/G cg03709012 chr19:19516395 GATAD2A 1.01 17.93 0.7 3.71e-51 Tonsillectomy; LIHC cis rs933688 1.000 rs10059163 chr5:90742444 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.86 18.23 0.7 2.43e-52 Smoking behavior; LIHC cis rs875971 0.508 rs6947808 chr7:66045082 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.28 -5.8 -0.3 1.52e-8 Aortic root size; LIHC trans rs2243480 1.000 rs34703416 chr7:65300642 A/G cg10756647 chr7:56101905 PSPH 1.1 13.52 0.59 1.17e-33 Diabetic kidney disease; LIHC cis rs10751667 1.000 rs6597972 chr11:928402 C/T cg10932868 chr11:921992 NA 0.36 6.82 0.35 4.25e-11 Alzheimer's disease (late onset); LIHC cis rs4716602 0.609 rs12386633 chr7:156158232 G/C cg16983916 chr7:156159713 NA -0.32 -5.84 -0.3 1.22e-8 Anti-saccade response; LIHC cis rs8067354 0.872 rs1292060 chr17:57913849 A/G cg13753209 chr17:57696993 CLTC 0.58 8.74 0.43 1.08e-16 Hemoglobin concentration; LIHC cis rs12464483 0.591 rs2602775 chr2:30883012 C/T cg17749961 chr2:30669863 LCLAT1 0.47 6.06 0.31 3.5e-9 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.69 -11.85 -0.54 2.34e-27 Colorectal cancer; LIHC cis rs4900538 0.819 rs72698591 chr14:102838896 G/A cg18135206 chr14:102964638 TECPR2 -0.94 -14.8 -0.62 1.2e-38 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg23782820 chr8:58130467 NA 0.33 5.95 0.31 6.66e-9 Developmental language disorder (linguistic errors); LIHC cis rs8062405 1.000 rs28403629 chr16:28854769 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs477692 0.637 rs7098619 chr10:131315856 C/T cg05714579 chr10:131428358 MGMT 0.41 6.64 0.34 1.27e-10 Response to temozolomide; LIHC cis rs17685 0.753 rs1637045 chr7:75703895 T/C cg01364799 chr7:75623366 TMEM120A -0.49 -7.34 -0.37 1.56e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs739401 0.611 rs7109088 chr11:3027485 G/T cg05729581 chr11:3078854 CARS -0.42 -5.92 -0.3 8.04e-9 Longevity; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg25026715 chr17:26989248 SUPT6H;SDF2 0.45 7.13 0.36 6.14e-12 Calcium levels; LIHC cis rs910316 1.000 rs876402 chr14:75601862 C/T cg11812906 chr14:75593930 NEK9 -0.73 -14.28 -0.61 1.29e-36 Height; LIHC cis rs6582630 0.555 rs10880612 chr12:38509427 A/G cg26384229 chr12:38710491 ALG10B 0.7 9.97 0.47 1.01e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs7520050 0.667 rs11211176 chr1:46223086 C/T cg03146154 chr1:46216737 IPP -0.53 -9.14 -0.44 5.84e-18 Red blood cell count;Reticulocyte count; LIHC trans rs2018683 1.000 rs2018683 chr7:29014195 G/T cg19402173 chr7:128379420 CALU -0.43 -6.83 -0.35 3.8e-11 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg14262678 chr6:151773367 RMND1;C6orf211 -0.64 -9.22 -0.45 3.09e-18 Menarche (age at onset); LIHC cis rs933688 1.000 rs9293568 chr5:90737845 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.2 0.66 3.29e-44 Smoking behavior; LIHC cis rs2834188 0.924 rs2850015 chr21:34697264 T/C cg14352951 chr21:34696688 IFNAR1 0.49 6.77 0.34 5.65e-11 Narcolepsy; LIHC trans rs1814175 0.615 rs11040654 chr11:49939485 T/G cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC trans rs75804782 0.521 rs1123472 chr2:239414355 C/T cg01134436 chr17:81009848 B3GNTL1 -0.7 -6.22 -0.32 1.41e-9 Morning vs. evening chronotype;Chronotype; LIHC trans rs2797160 0.651 rs1268093 chr6:126029235 C/T cg05039488 chr6:79577232 IRAK1BP1 0.5 7.62 0.38 2.5e-13 Endometrial cancer; LIHC cis rs6582630 0.555 rs10880520 chr12:38464111 C/T cg26384229 chr12:38710491 ALG10B 0.66 9.13 0.44 6.3e-18 Drug-induced liver injury (flucloxacillin); LIHC cis rs7520050 0.931 rs11576305 chr1:46460046 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.43 6.34 0.32 7.42e-10 Red blood cell count;Reticulocyte count; LIHC cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.79 0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs7044106 0.762 rs1158553 chr9:123400974 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 8.0 0.4 1.94e-14 Hip circumference adjusted for BMI; LIHC cis rs3770081 1.000 rs56977454 chr2:86204014 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -7.9 -0.39 3.92e-14 Facial emotion recognition (sad faces); LIHC cis rs7918232 0.941 rs1755399 chr10:27394958 A/G cg14442939 chr10:27389572 ANKRD26 0.74 7.08 0.36 8.34e-12 Breast cancer; LIHC cis rs9916302 0.904 rs588193 chr17:37440439 A/C cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC cis rs317689 0.690 rs317656 chr12:69681101 T/A cg20891283 chr12:69753455 YEATS4 0.53 7.68 0.38 1.64e-13 Response to diuretic therapy; LIHC cis rs28374715 0.662 rs691907 chr15:41474657 C/G cg18705301 chr15:41695430 NDUFAF1 0.83 9.69 0.46 9.18e-20 Ulcerative colitis; LIHC cis rs7188697 0.848 rs37062 chr16:58567238 A/G cg02549819 chr16:58548995 SETD6 -0.45 -7.16 -0.36 5.04e-12 QT interval; LIHC cis rs722599 0.683 rs2058918 chr14:75288518 A/G cg11812906 chr14:75593930 NEK9 0.43 6.54 0.33 2.18e-10 IgG glycosylation; LIHC cis rs60871478 0.898 rs35928069 chr7:823067 G/C cg04727924 chr7:799746 HEATR2 -0.59 -8.58 -0.42 3.48e-16 Cerebrospinal P-tau181p levels; LIHC cis rs11711311 1.000 rs2603792 chr3:113509187 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.41 7.77 0.39 9.55e-14 IgG glycosylation; LIHC cis rs546131 0.928 rs572690 chr11:34833614 A/G cg06937548 chr11:34938143 PDHX;APIP 0.58 7.88 0.39 4.42e-14 Lung disease severity in cystic fibrosis; LIHC cis rs7617773 0.817 rs3729577 chr3:48228994 A/C cg11946769 chr3:48343235 NME6 0.89 10.95 0.51 4.08e-24 Coronary artery disease; LIHC cis rs11690935 1.000 rs1554166 chr2:172541609 G/T cg13550731 chr2:172543902 DYNC1I2 -0.92 -18.38 -0.7 5.75e-53 Schizophrenia; LIHC cis rs6840360 0.571 rs1978955 chr4:152509509 G/A cg22705602 chr4:152727874 NA -0.32 -6.17 -0.32 1.98e-9 Intelligence (multi-trait analysis); LIHC cis rs67478160 0.619 rs12897150 chr14:104319530 A/T cg08213375 chr14:104286397 PPP1R13B 0.66 12.4 0.56 2.11e-29 Schizophrenia; LIHC cis rs6061231 0.556 rs6121571 chr20:60977323 T/G cg24112000 chr20:60950667 NA -0.59 -8.77 -0.43 8.72e-17 Colorectal cancer; LIHC cis rs4716602 0.596 rs10253193 chr7:156157801 C/T cg16983916 chr7:156159713 NA -0.34 -6.03 -0.31 4.32e-9 Anti-saccade response; LIHC cis rs1577917 1.000 rs10498958 chr6:86649705 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.46 7.4 0.37 1.08e-12 Response to antipsychotic treatment; LIHC cis rs1401999 1.000 rs2313217 chr3:183635997 A/G cg01324343 chr3:183735012 ABCC5 0.73 11.96 0.54 8.84e-28 Anterior chamber depth; LIHC cis rs7940866 0.804 rs10894287 chr11:130808483 C/T cg12179176 chr11:130786555 SNX19 0.62 9.31 0.45 1.62e-18 Schizophrenia; LIHC cis rs12200782 0.530 rs9379892 chr6:26582414 G/A cg11502198 chr6:26597334 ABT1 0.86 11.32 0.52 1.86e-25 Small cell lung carcinoma; LIHC cis rs12188164 0.561 rs2251843 chr5:457955 C/T cg08916839 chr5:415575 AHRR -0.29 -6.35 -0.32 6.71e-10 Cystic fibrosis severity; LIHC cis rs7264396 0.690 rs17093156 chr20:34438583 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.83 -0.51 1.07e-23 Total cholesterol levels; LIHC cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg16262614 chr3:133464971 TF 0.28 6.21 0.32 1.56e-9 Iron status biomarkers; LIHC cis rs11098499 0.863 rs34308924 chr4:120481431 T/C cg09307838 chr4:120376055 NA 0.75 11.33 0.52 1.79e-25 Corneal astigmatism; LIHC cis rs2408955 0.522 rs6580650 chr12:48418556 G/T cg21466736 chr12:48725269 NA 0.6 8.2 0.41 4.83e-15 Glycated hemoglobin levels; LIHC cis rs2236918 1.000 rs2526704 chr1:242015820 A/G cg17736920 chr1:242011382 EXO1 0.58 8.23 0.41 3.87e-15 Menopause (age at onset); LIHC cis rs1577917 0.958 rs67024565 chr6:86553997 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.46 -7.32 -0.37 1.75e-12 Response to antipsychotic treatment; LIHC cis rs4654899 0.758 rs7521711 chr1:21400218 A/G cg08539965 chr1:21396338 EIF4G3 0.33 5.76 0.3 1.91e-8 Superior frontal gyrus grey matter volume; LIHC trans rs73186030 0.920 rs73186059 chr3:122051183 T/C cg13973942 chr17:977984 ABR 0.47 6.06 0.31 3.6e-9 Serum parathyroid hormone levels; LIHC trans rs2727020 0.729 rs4315497 chr11:49214499 G/A cg15704280 chr7:45808275 SEPT13 0.88 16.29 0.66 1.46e-44 Coronary artery disease; LIHC cis rs12915845 0.545 rs7402591 chr15:89078434 T/C cg05013243 chr15:89149849 MIR1179 -0.39 -6.86 -0.35 3.31e-11 Menarche (age at onset); LIHC cis rs7223966 0.621 rs28571160 chr17:61638723 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.54 5.84 0.3 1.2e-8 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.62 -0.34 1.38e-10 Gut microbiome composition (summer); LIHC trans rs10197940 0.578 rs2432957 chr2:152287897 A/C cg23633937 chr19:45575142 ZNF296 0.34 6.12 0.31 2.5e-9 Lung cancer; LIHC cis rs7224314 1.000 rs62084081 chr17:65387148 G/C cg01507342 chr17:65387096 PITPNC1 -0.5 -6.38 -0.33 5.73e-10 Diisocyanate-induced asthma; LIHC cis rs2153535 0.580 rs1932280 chr6:8473654 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC trans rs208520 0.661 rs150263 chr6:66777620 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.78 -8.74 -0.43 1.04e-16 Exhaled nitric oxide output; LIHC cis rs780096 0.526 rs13472 chr2:27600239 G/A cg21747090 chr2:27597821 SNX17 -0.42 -6.32 -0.32 8.03e-10 Total body bone mineral density; LIHC cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg00280220 chr17:61926910 NA -0.42 -6.82 -0.35 4.15e-11 Prudent dietary pattern; LIHC cis rs2976388 1.000 rs2920298 chr8:143763043 A/G cg06565975 chr8:143823917 SLURP1 -0.31 -5.91 -0.3 8.23e-9 Urinary tract infection frequency; LIHC cis rs6500602 0.727 rs1477123 chr16:4560627 T/A cg08645402 chr16:4508243 NA 0.38 6.87 0.35 3.11e-11 Schizophrenia; LIHC cis rs7116495 1.000 rs7124000 chr11:71754338 T/C cg26138937 chr11:71823887 C11orf51 -0.72 -7.15 -0.36 5.37e-12 Severe influenza A (H1N1) infection; LIHC cis rs77633900 0.614 rs1443110 chr15:76928322 C/T cg21673338 chr15:77095150 SCAPER 0.46 7.06 0.36 9.24e-12 Non-glioblastoma glioma;Glioma; LIHC cis rs4631830 0.863 rs7081532 chr10:51526093 A/G cg20129853 chr10:51489980 NA -0.41 -8.93 -0.43 2.63e-17 Prostate-specific antigen levels; LIHC cis rs597539 0.690 rs578791 chr11:68625809 C/T cg04772025 chr11:68637568 NA 0.45 5.82 0.3 1.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs921968 0.541 rs1863704 chr2:219562675 C/T cg02985541 chr2:219472218 PLCD4 -0.38 -5.98 -0.31 5.63e-9 Mean corpuscular hemoglobin concentration; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11505180 chr12:75724112 CAPS2 -0.45 -6.98 -0.35 1.51e-11 Pancreatic cancer; LIHC trans rs11039798 1.000 rs12281162 chr11:48650491 T/C cg15704280 chr7:45808275 SEPT13 0.59 6.12 0.31 2.49e-9 Axial length; LIHC cis rs2070488 0.745 rs9838792 chr3:38546726 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.68 -11.13 -0.52 9.44e-25 Electrocardiographic conduction measures; LIHC cis rs7618915 0.679 rs6802320 chr3:52241835 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.39 6.15 0.32 2.19e-9 Bipolar disorder; LIHC cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg23172400 chr8:95962367 TP53INP1 -0.35 -7.86 -0.39 5.08e-14 Type 2 diabetes; LIHC cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.55 -7.75 -0.39 1.06e-13 Lymphocyte counts; LIHC cis rs9788682 0.895 rs3813570 chr15:78832832 T/C cg06917634 chr15:78832804 PSMA4 -0.55 -7.87 -0.39 4.62e-14 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs12142240 0.698 rs41293285 chr1:46808426 C/T cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC trans rs7674212 0.570 rs6810571 chr4:104086787 G/T cg16471864 chr4:38666270 KLF3;FLJ13197 -0.45 -6.34 -0.32 7.18e-10 Type 2 diabetes; LIHC cis rs6456156 0.586 rs6456154 chr6:167472256 C/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.69 -0.43 1.56e-16 Primary biliary cholangitis; LIHC cis rs6964587 1.000 rs4727267 chr7:91570290 G/C cg17063962 chr7:91808500 NA -1.01 -19.21 -0.72 2.67e-56 Breast cancer; LIHC trans rs3780486 0.846 rs913214 chr9:33135085 G/A cg20290983 chr6:43655470 MRPS18A 1.19 30.89 0.86 5.55e-101 IgG glycosylation; LIHC trans rs1814175 0.669 rs11040473 chr11:49703813 C/T cg03929089 chr4:120376271 NA -0.58 -9.63 -0.46 1.4e-19 Height; LIHC cis rs4688759 0.719 rs73079018 chr3:49875327 T/C cg00383909 chr3:49044727 WDR6 0.92 6.53 0.33 2.39e-10 Blood protein levels; LIHC cis rs4843747 0.671 rs72818577 chr16:88111181 G/A cg06050784 chr16:88016603 BANP 0.36 6.54 0.33 2.26e-10 Menopause (age at onset); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg09220050 chr20:48770642 TMEM189;TMEM189-UBE2V1 -0.45 -6.14 -0.32 2.24e-9 Systolic blood pressure; LIHC cis rs7249142 0.561 rs4808185 chr19:19296217 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.38 -6.27 -0.32 1.06e-9 IgG glycosylation; LIHC cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg27170947 chr2:26402098 FAM59B 0.67 8.31 0.41 2.32e-15 Gut microbiome composition (summer); LIHC cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg16132339 chr22:24313637 DDTL;DDT 0.77 14.89 0.63 5.41e-39 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6503863 1 rs6503863 chr17:56517034 G/A cg05425664 chr17:57184151 TRIM37 -0.49 -7.18 -0.36 4.47e-12 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs11122281 chr1:231519842 A/G cg06096015 chr1:231504339 EGLN1 0.48 8.71 0.43 1.34e-16 Hemoglobin concentration; LIHC trans rs11098499 0.954 rs67265404 chr4:120359270 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.81 0.47 3.5e-20 Corneal astigmatism; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg17432898 chr6:15663501 DTNBP1 -0.42 -6.4 -0.33 5.27e-10 Migraine with aura; LIHC cis rs35110281 0.774 rs2838321 chr21:44995488 A/T cg04455712 chr21:45112962 RRP1B 0.46 7.98 0.4 2.17e-14 Mean corpuscular volume; LIHC cis rs990171 0.607 rs1558642 chr2:102763960 T/G cg22835712 chr2:102737379 NA 0.52 7.25 0.37 2.74e-12 Lymphocyte counts; LIHC cis rs35110281 0.633 rs4818860 chr21:45119617 C/T cg04455712 chr21:45112962 RRP1B 0.48 8.54 0.42 4.39e-16 Mean corpuscular volume; LIHC cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg21782813 chr7:2030301 MAD1L1 0.49 8.79 0.43 7.58e-17 Bipolar disorder and schizophrenia; LIHC cis rs875971 0.545 rs316328 chr7:65608838 A/G cg11764359 chr7:65958608 NA -0.51 -7.27 -0.37 2.41e-12 Aortic root size; LIHC cis rs3862260 0.509 rs7552885 chr1:120164966 C/T cg11530693 chr1:120165357 ZNF697 0.48 7.59 0.38 3.02e-13 Systemic lupus erythematosus; LIHC cis rs10744422 1.000 rs4759382 chr12:123347609 C/T cg18912006 chr12:123335444 HIP1R 0.59 7.26 0.37 2.66e-12 Schizophrenia; LIHC cis rs3099143 1.000 rs4886832 chr15:77121196 G/A cg21673338 chr15:77095150 SCAPER 0.48 7.35 0.37 1.43e-12 Recalcitrant atopic dermatitis; LIHC cis rs3008870 0.583 rs3008892 chr1:67373558 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.88 12.94 0.57 1.92e-31 Lymphocyte percentage of white cells; LIHC cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg22105103 chr4:187893119 NA 0.34 8.48 0.42 7.07e-16 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20361540 chr12:123380447 VPS37B -0.44 -6.31 -0.32 8.8e-10 Cognitive function; LIHC trans rs6912958 0.712 rs9444525 chr6:88324142 T/C cg23605328 chr1:201951606 RNPEP 0.4 6.36 0.33 6.53e-10 Monocyte percentage of white cells; LIHC cis rs16828019 0.929 rs35883594 chr1:41744093 A/G cg20697417 chr1:41786797 NA 0.36 6.6 0.34 1.59e-10 Intelligence (multi-trait analysis); LIHC cis rs12474201 0.928 rs34186074 chr2:46965010 T/C cg06386533 chr2:46925753 SOCS5 0.75 8.45 0.42 8.21e-16 Height; LIHC cis rs2439831 0.850 rs2277531 chr15:44069069 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.42 0.41 1.09e-15 Lung cancer in ever smokers; LIHC cis rs909341 0.868 rs6089961 chr20:62349491 G/A cg03999872 chr20:62272968 STMN3 -0.45 -6.75 -0.34 6.43e-11 Atopic dermatitis; LIHC cis rs116095464 0.558 rs9688136 chr5:229348 T/C cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2576037 0.583 rs680018 chr18:44409167 T/A cg19077165 chr18:44547161 KATNAL2 -0.47 -6.8 -0.35 4.74e-11 Personality dimensions; LIHC cis rs2404602 0.716 rs284895 chr15:76751225 C/G cg03037974 chr15:76606532 NA -0.77 -15.8 -0.65 1.35e-42 Blood metabolite levels; LIHC cis rs9378688 0.722 rs9392375 chr6:2233061 C/T cg12303981 chr6:2244766 GMDS -0.49 -6.29 -0.32 9.47e-10 Caudate nucleus volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18429685 chr19:59085257 MZF1;LOC100131691 0.44 6.69 0.34 9.08e-11 Cognitive function; LIHC cis rs7582720 1.000 rs72936847 chr2:203774748 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC trans rs12478296 0.685 rs67829386 chr2:242992276 T/A cg01596870 chr19:55963115 NA -0.65 -9.28 -0.45 2e-18 Obesity-related traits; LIHC cis rs7647973 0.593 rs9870755 chr3:49809841 A/G cg03060546 chr3:49711283 APEH 0.57 6.6 0.34 1.54e-10 Menarche (age at onset); LIHC cis rs7075426 0.524 rs12411744 chr10:88245075 G/A cg07322936 chr10:88137208 NA 0.46 6.17 0.32 1.92e-9 Migraine without aura; LIHC cis rs769267 0.930 rs1063966 chr19:19616742 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.4 6.08 0.31 3.17e-9 Tonsillectomy; LIHC cis rs8180040 0.654 rs6766230 chr3:47196209 C/A cg16586182 chr3:47516702 SCAP -0.48 -8.46 -0.42 7.82e-16 Colorectal cancer; LIHC cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg04267008 chr7:1944627 MAD1L1 -0.58 -9.0 -0.44 1.6e-17 Bipolar disorder and schizophrenia; LIHC cis rs858239 0.600 rs7787110 chr7:23138474 C/T cg23682824 chr7:23144976 KLHL7 0.43 6.4 0.33 5.1e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs4423214 0.765 rs2002064 chr11:71163420 A/G cg05163923 chr11:71159392 DHCR7 -0.6 -8.04 -0.4 1.44e-14 Vitamin D levels; LIHC cis rs7412746 0.658 rs4970988 chr1:150950062 A/G cg17724175 chr1:150552817 MCL1 -0.37 -7.29 -0.37 2.2e-12 Melanoma; LIHC cis rs6684514 1.000 rs12122180 chr1:156244559 G/A cg16558208 chr1:156270281 VHLL 0.54 10.24 0.48 1.18e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs2439831 0.681 rs28594657 chr15:43588888 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.77 9.38 0.45 9.49e-19 Lung cancer in ever smokers; LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg11618577 chr2:27665543 KRTCAP3 -0.42 -5.79 -0.3 1.56e-8 Total body bone mineral density; LIHC cis rs6690583 0.697 rs10873684 chr1:85522196 T/C cg22153463 chr1:85462885 MCOLN2 -0.58 -9.05 -0.44 1.1e-17 Serum sulfate level; LIHC cis rs6450176 0.564 rs406621 chr5:53326232 T/C ch.5.1024479R chr5:53302184 ARL15 -0.75 -13.59 -0.59 6.42e-34 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1448094 0.512 rs11832503 chr12:86240797 A/G cg02569458 chr12:86230093 RASSF9 0.47 6.28 0.32 1.02e-9 Major depressive disorder; LIHC trans rs7618501 1.000 rs11709680 chr3:49745188 C/T cg21582582 chr3:182698605 DCUN1D1 -0.51 -6.66 -0.34 1.12e-10 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs79149102 0.579 rs74023936 chr15:75362084 C/T cg09165964 chr15:75287851 SCAMP5 -0.56 -7.42 -0.37 9.59e-13 Lung cancer; LIHC cis rs2303745 0.544 rs12710308 chr19:17395879 T/A cg04248312 chr19:17393744 ANKLE1 -0.74 -12.36 -0.56 2.83e-29 Systemic lupus erythematosus; LIHC cis rs6089584 1.000 rs6142910 chr20:60562181 C/A cg12751644 chr20:60527061 NA -0.37 -6.09 -0.31 3.12e-9 Body mass index; LIHC cis rs9818758 0.607 rs3923475 chr3:49055788 G/T cg06212747 chr3:49208901 KLHDC8B -0.69 -5.91 -0.3 8.11e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs8005677 1.000 rs11157930 chr14:23403171 T/G cg25600027 chr14:23388339 RBM23 -0.41 -5.94 -0.31 6.93e-9 Cognitive ability (multi-trait analysis); LIHC cis rs2274273 1.000 rs8011834 chr14:55625977 A/C cg04306507 chr14:55594613 LGALS3 0.33 6.17 0.32 1.98e-9 Protein biomarker; LIHC cis rs295137 0.799 rs4145969 chr2:201139961 C/T cg23649088 chr2:200775458 C2orf69 -0.47 -6.48 -0.33 3.16e-10 Asthma (bronchodilator response); LIHC cis rs6138458 0.847 rs56312312 chr20:24959386 C/A cg26195577 chr20:24973756 C20orf3 1.16 13.92 0.6 3.37e-35 Blood protein levels; LIHC cis rs34779708 0.897 rs12764820 chr10:35386321 G/A cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg25894440 chr7:65020034 NA 0.56 6.48 0.33 3.21e-10 Diabetic kidney disease; LIHC cis rs875971 0.862 rs10950033 chr7:65739673 A/G cg18876405 chr7:65276391 NA -0.35 -6.37 -0.33 6.12e-10 Aortic root size; LIHC cis rs7937682 0.889 rs516263 chr11:111484719 A/C cg09085632 chr11:111637200 PPP2R1B -0.9 -10.73 -0.5 2.4e-23 Primary sclerosing cholangitis; LIHC cis rs7615952 0.641 rs60839048 chr3:125807938 G/A cg05084668 chr3:125655381 ALG1L -0.39 -5.99 -0.31 5.24e-9 Blood pressure (smoking interaction); LIHC cis rs9790314 0.601 rs1450519 chr3:161094930 A/G cg06054026 chr3:161089429 C3orf57 -0.41 -6.75 -0.34 6.27e-11 Morning vs. evening chronotype; LIHC cis rs875971 0.825 rs801202 chr7:66023929 C/T cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.35e-9 Aortic root size; LIHC cis rs7520050 0.966 rs12760175 chr1:46447840 G/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.81 0.3 1.4e-8 Red blood cell count;Reticulocyte count; LIHC cis rs138857 0.515 rs9616375 chr22:50310600 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.83 -7.23 -0.36 3.22e-12 Mean platelet volume; LIHC cis rs11098499 0.955 rs6815725 chr4:120158410 C/A cg09307838 chr4:120376055 NA 0.74 10.9 0.51 6.12e-24 Corneal astigmatism; LIHC cis rs8192282 0.698 rs6427729 chr1:154518874 G/A cg16683920 chr1:154474344 TDRD10;SHE -0.5 -6.15 -0.32 2.14e-9 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); LIHC cis rs1577917 1.000 rs34852683 chr6:86702330 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.38 -0.33 5.85e-10 Response to antipsychotic treatment; LIHC cis rs600806 0.850 rs11102976 chr1:109917540 G/C cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.17 -0.36 4.54e-12 Intelligence (multi-trait analysis); LIHC cis rs77633900 0.614 rs2439982 chr15:76925071 T/G cg21673338 chr15:77095150 SCAPER -0.49 -7.27 -0.37 2.42e-12 Non-glioblastoma glioma;Glioma; LIHC trans rs1814175 0.647 rs10839394 chr11:49844747 T/C cg18944383 chr4:111397179 ENPEP 0.26 6.65 0.34 1.13e-10 Height; LIHC trans rs6934970 1.000 rs12199472 chr6:113014691 A/G cg09308777 chr6:169852575 NA 0.6 6.21 0.32 1.5e-9 Bipolar disorder (body mass index interaction); LIHC cis rs4803468 1.000 rs6508977 chr19:41909346 A/G cg09537434 chr19:41945824 ATP5SL -1.01 -21.3 -0.76 1.14e-64 Height; LIHC cis rs5758511 0.680 rs5758681 chr22:42645091 A/G cg20195005 chr22:42527684 CYP2D6 0.3 5.79 0.3 1.56e-8 Birth weight; LIHC cis rs4642101 0.597 rs9839769 chr3:12821405 C/T cg24848339 chr3:12840334 CAND2 0.31 6.45 0.33 3.92e-10 QRS complex (12-leadsum); LIHC cis rs1997103 0.954 rs56030000 chr7:55405750 A/G cg17469321 chr7:55412551 NA 0.48 7.09 0.36 7.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg06481639 chr22:41940642 POLR3H -0.73 -7.71 -0.38 1.4e-13 Vitiligo; LIHC cis rs17401966 1.000 rs1339458 chr1:10328338 C/T cg19773385 chr1:10388646 KIF1B -0.49 -8.38 -0.41 1.4e-15 Hepatocellular carcinoma; LIHC trans rs1814175 0.645 rs4625470 chr11:49983769 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.87 0.35 3.09e-11 Height; LIHC cis rs892961 1.000 rs2164449 chr17:75401190 G/A cg05865280 chr17:75406074 SEPT9 0.6 12.07 0.55 3.56e-28 Airflow obstruction; LIHC cis rs7937682 0.847 rs583032 chr11:111432757 C/T cg09085632 chr11:111637200 PPP2R1B -0.86 -10.47 -0.49 2e-22 Primary sclerosing cholangitis; LIHC cis rs61008539 0.741 rs11767322 chr7:867405 A/G cg24004478 chr7:855632 UNC84A 0.47 6.68 0.34 9.9e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs11190604 1.000 rs7905961 chr10:102297391 G/C cg07080220 chr10:102295463 HIF1AN 0.53 7.74 0.39 1.11e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10744422 0.925 rs2061098 chr12:123349410 T/C cg18912006 chr12:123335444 HIP1R -0.63 -7.09 -0.36 7.67e-12 Schizophrenia; LIHC cis rs1005277 0.579 rs116912400 chr10:38479207 G/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.27 -0.32 1.06e-9 Extrinsic epigenetic age acceleration; LIHC cis rs875971 0.660 rs6460308 chr7:66084740 T/C cg11764359 chr7:65958608 NA -0.72 -10.93 -0.51 4.85e-24 Aortic root size; LIHC cis rs7395581 0.959 rs7120118 chr11:47286290 T/C cg26139080 chr11:47293733 MADD -0.5 -8.43 -0.41 9.56e-16 HDL cholesterol; LIHC cis rs1997103 1.000 rs1997102 chr7:55399322 A/C cg17469321 chr7:55412551 NA -0.48 -7.05 -0.36 1e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs15676 0.783 rs7033070 chr9:131586374 G/A cg00228799 chr9:131580591 ENDOG -0.47 -6.85 -0.35 3.45e-11 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21574429 chr6:143381827 AIG1 -0.4 -6.05 -0.31 3.75e-9 Pancreatic cancer; LIHC trans rs3780486 0.505 rs10117038 chr9:33122626 T/C cg04842962 chr6:43655489 MRPS18A 0.87 18.51 0.71 1.69e-53 IgG glycosylation; LIHC cis rs7095607 0.538 rs2634706 chr10:69917590 A/C cg18986048 chr10:69913749 MYPN 0.5 7.54 0.38 4.13e-13 Lung function (FVC); LIHC cis rs2832191 0.679 rs2705659 chr21:30363908 G/C cg08807101 chr21:30365312 RNF160 0.79 12.0 0.54 6.26e-28 Dental caries; LIHC cis rs1403694 0.515 rs822362 chr3:186453065 A/C cg12454167 chr3:186435060 KNG1 0.32 7.49 0.38 6.09e-13 Blood protein levels; LIHC cis rs4294134 0.832 rs11772708 chr7:135264737 A/G cg20392616 chr7:135392013 SLC13A4 0.38 6.06 0.31 3.61e-9 Paget's disease; LIHC cis rs11626933 0.589 rs10140761 chr14:90740588 G/C cg04374321 chr14:90722782 PSMC1 -0.54 -8.9 -0.43 3.24e-17 Gut microbiota (bacterial taxa); LIHC cis rs921968 0.565 rs6436083 chr2:219639719 C/T cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7264396 0.635 rs6121102 chr20:34544274 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.59 -0.5 7.31e-23 Total cholesterol levels; LIHC cis rs4423214 0.802 rs2276358 chr11:71184498 G/A cg05163923 chr11:71159392 DHCR7 -0.61 -8.0 -0.4 1.96e-14 Vitamin D levels; LIHC cis rs8180040 0.934 rs4858811 chr3:47480524 G/C cg16586182 chr3:47516702 SCAP 0.61 11.81 0.54 3.13e-27 Colorectal cancer; LIHC cis rs9871864 0.868 rs12491544 chr3:20358326 A/G cg00235661 chr3:20228976 SGOL1 -0.31 -5.88 -0.3 9.82e-9 Behavioural disinhibition (generation interaction); LIHC cis rs7212938 0.509 rs62068170 chr17:38103210 G/A cg17467752 chr17:38218738 THRA 0.42 6.82 0.35 4.15e-11 Asthma and hay fever; LIHC cis rs9311474 0.502 rs4687624 chr3:52563572 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.5 8.59 0.42 3.13e-16 Electroencephalogram traits; LIHC cis rs12477438 0.520 rs11123765 chr2:99768064 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg07133347 chr1:107600762 PRMT6 -0.44 -6.66 -0.34 1.1e-10 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17854409 1.000 rs6010770 chr20:61494225 G/T cg06598544 chr20:61472147 COL9A3 -0.77 -7.39 -0.37 1.17e-12 Obesity-related traits; LIHC cis rs1371867 0.846 rs1788197 chr8:101290928 T/C cg06002616 chr8:101225028 SPAG1 -0.35 -5.76 -0.3 1.85e-8 Atrioventricular conduction; LIHC cis rs853679 0.517 rs9357065 chr6:28129580 T/C cg16479474 chr6:28041457 NA 0.46 6.44 0.33 4.17e-10 Depression; LIHC cis rs7772486 0.875 rs6930975 chr6:146387111 C/T cg13319975 chr6:146136371 FBXO30 -0.35 -5.87 -0.3 1.05e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs763121 0.785 rs6001203 chr22:39099602 T/C cg14440974 chr22:39074834 NA -0.37 -6.25 -0.32 1.21e-9 Menopause (age at onset); LIHC cis rs875971 1.000 rs6460292 chr7:65810075 G/A cg18876405 chr7:65276391 NA -0.37 -6.73 -0.34 7.2e-11 Aortic root size; LIHC cis rs67460515 0.563 rs4521287 chr3:160812752 C/T cg03342759 chr3:160939853 NMD3 -0.59 -8.46 -0.42 7.73e-16 Parkinson's disease; LIHC cis rs3806843 0.900 rs2262576 chr5:140135536 T/C cg19875535 chr5:140030758 IK -0.35 -5.79 -0.3 1.58e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs1568889 1.000 rs61889026 chr11:28274803 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.76 0.34 5.81e-11 Bipolar disorder; LIHC cis rs7552404 0.807 rs2066183 chr1:76153745 A/G cg22875332 chr1:76189707 ACADM 0.47 7.35 0.37 1.49e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9916302 0.904 rs1077715 chr17:37683548 A/T cg03013999 chr17:37608204 MED1 0.34 5.71 0.3 2.42e-8 Glomerular filtration rate (creatinine); LIHC cis rs2953174 0.786 rs2953145 chr2:241515596 C/G cg07929629 chr2:241523174 NA -0.59 -7.09 -0.36 7.54e-12 Bipolar disorder; LIHC cis rs11676348 0.935 rs4674250 chr2:218977531 G/A cg00012203 chr2:219082015 ARPC2 -0.53 -7.14 -0.36 5.81e-12 Ulcerative colitis; LIHC cis rs7223966 1.000 rs7209435 chr17:61712964 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.23 0.36 3.16e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs593982 1.000 rs650619 chr11:65506483 G/A cg08755490 chr11:65554678 OVOL1 0.55 8.6 0.42 2.85e-16 Atopic dermatitis; LIHC cis rs9790314 0.628 rs4342141 chr3:160783922 T/C cg03342759 chr3:160939853 NMD3 -0.61 -8.0 -0.4 1.94e-14 Morning vs. evening chronotype; LIHC cis rs875971 0.545 rs6969224 chr7:65834998 T/G cg11764359 chr7:65958608 NA 0.6 8.44 0.42 8.87e-16 Aortic root size; LIHC cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg03517284 chr6:25882590 NA -0.44 -6.71 -0.34 8.23e-11 Height; LIHC cis rs2153535 0.580 rs9378551 chr6:8463744 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.65 0.42 1.97e-16 Motion sickness; LIHC cis rs17685 0.753 rs1104878 chr7:75685593 G/T cg01364799 chr7:75623366 TMEM120A -0.51 -7.81 -0.39 6.99e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs8072100 0.840 rs12452796 chr17:45479733 G/T cg25173405 chr17:45401733 C17orf57 0.41 5.71 0.3 2.45e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs11014306 1.000 rs6482455 chr10:25200457 C/G cg19056833 chr13:114749079 RASA3 0.62 6.12 0.31 2.63e-9 Metabolite levels (Pyroglutamine); LIHC cis rs763014 1.000 rs763014 chr16:675680 T/C cg07343612 chr16:622815 PIGQ -0.87 -15.07 -0.63 1.04e-39 Height; LIHC cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.95e-9 Menopause (age at onset); LIHC cis rs1912483 0.545 rs35161461 chr17:45401757 A/G cg25173405 chr17:45401733 C17orf57 -0.56 -7.16 -0.36 5.13e-12 Coronary artery disease; LIHC cis rs7312933 0.612 rs10785334 chr12:42620377 A/G cg01256987 chr12:42539512 GXYLT1 0.42 7.01 0.35 1.27e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11792861 0.781 rs11793272 chr9:111762102 G/A cg13535736 chr9:111863775 C9orf5 -0.41 -6.11 -0.31 2.68e-9 Menarche (age at onset); LIHC cis rs67478160 0.643 rs11847468 chr14:104220295 G/A cg08213375 chr14:104286397 PPP1R13B 0.64 12.68 0.57 1.8e-30 Schizophrenia; LIHC cis rs6977660 1.000 rs12666159 chr7:19804199 T/C cg07541023 chr7:19748670 TWISTNB 0.39 6.17 0.32 1.9e-9 Thyroid stimulating hormone; LIHC cis rs13108904 0.517 rs13128825 chr4:1334007 G/A cg05665937 chr4:1216051 CTBP1 0.44 5.83 0.3 1.25e-8 Obesity-related traits; LIHC cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg12463550 chr7:65579703 CRCP 0.68 7.01 0.35 1.25e-11 Diabetic kidney disease; LIHC cis rs2629540 0.847 rs12247543 chr10:126419743 G/C cg08799069 chr10:126477246 METTL10 0.45 7.21 0.36 3.73e-12 Cocaine dependence; LIHC cis rs208515 0.556 rs12201658 chr6:66678457 T/C cg07460842 chr6:66804631 NA 0.76 8.85 0.43 4.72e-17 Exhaled nitric oxide levels; LIHC cis rs240764 0.817 rs2036052 chr6:101154909 G/A cg09795085 chr6:101329169 ASCC3 -0.54 -7.51 -0.38 5.06e-13 Neuroticism; LIHC cis rs1506636 1.000 rs12706545 chr7:123348744 C/T cg03229431 chr7:123269106 ASB15 -0.57 -12.0 -0.54 6.31e-28 Plateletcrit;Platelet count; LIHC trans rs10915437 0.516 rs10915445 chr1:4197642 G/A cg23269655 chr10:75541687 CHCHD1 0.4 6.04 0.31 4e-9 Migraine - clinic-based; LIHC cis rs7635838 0.826 rs9867963 chr3:11469126 C/T cg00170343 chr3:11313890 ATG7 0.47 7.15 0.36 5.25e-12 HDL cholesterol; LIHC cis rs9914988 0.943 rs11651867 chr17:27147248 T/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.85 -0.35 3.41e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs2731664 0.792 rs335468 chr5:176892349 A/G cg23176889 chr5:176863531 GRK6 0.68 12.1 0.55 2.61e-28 Intelligence (multi-trait analysis); LIHC cis rs238295 0.766 rs6139762 chr20:5546694 C/T cg24001556 chr20:5591874 RP5-1022P6.2 0.52 7.13 0.36 5.84e-12 Occipital cortical area (total cortical area interaction); LIHC cis rs4407350 0.756 rs6519877 chr22:44890192 T/G cg26276947 chr22:44892394 LDOC1L 0.32 6.0 0.31 4.89e-9 Intelligence (multi-trait analysis); LIHC cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.15e-51 Menopause (age at onset); LIHC cis rs243505 0.559 rs2072407 chr7:148508833 A/G cg09806900 chr7:148480153 CUL1 0.4 5.91 0.3 8.45e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9394841 0.646 rs9369313 chr6:41847065 C/T cg08135965 chr6:41755394 TOMM6 0.44 5.74 0.3 2.04e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg27286337 chr10:134555280 INPP5A 0.94 13.48 0.59 1.58e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs6435862 0.500 rs12477063 chr2:215673664 C/T cg04004882 chr2:215674386 BARD1 -0.58 -8.74 -0.43 1.06e-16 Neuroblastoma (high-risk); LIHC cis rs9896933 0.830 rs113051447 chr17:80791806 A/G cg20578329 chr17:80767326 TBCD -0.62 -6.37 -0.33 6.04e-10 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs2625529 0.818 rs16956241 chr15:72111688 G/T cg16672083 chr15:72433130 SENP8 -0.32 -6.03 -0.31 4.36e-9 Red blood cell count; LIHC cis rs4759375 1.000 rs28581850 chr12:123871717 T/C cg00376283 chr12:123451042 ABCB9 0.49 6.31 0.32 8.6e-10 HDL cholesterol; LIHC trans rs2352908 0.786 rs12892499 chr14:49431047 C/G cg16568472 chr20:3190600 ITPA -0.45 -6.09 -0.31 3.12e-9 Social communication problems; LIHC cis rs11628318 0.853 rs8003309 chr14:103050143 C/G cg23461800 chr14:103021989 NA -0.54 -7.48 -0.37 6.4e-13 Platelet count; LIHC cis rs9942416 0.660 rs194137 chr5:74978857 G/A cg19683494 chr5:74908142 NA -0.58 -7.57 -0.38 3.52e-13 Age-related disease endophenotypes; LIHC cis rs2153535 0.580 rs9328478 chr6:8519183 A/G cg21535247 chr6:8435926 SLC35B3 0.62 8.22 0.41 4.22e-15 Motion sickness; LIHC cis rs10751667 1.000 rs7395691 chr11:985006 T/C cg10932868 chr11:921992 NA 0.36 6.68 0.34 9.72e-11 Alzheimer's disease (late onset); LIHC cis rs13427251 0.903 rs6746402 chr2:100150443 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.5 -6.32 -0.32 7.99e-10 Chronic sinus infection; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.58 -0.34 1.74e-10 Total body bone mineral density; LIHC cis rs9916302 0.706 rs1874226 chr17:37729031 C/T cg07936489 chr17:37558343 FBXL20 0.84 12.1 0.55 2.68e-28 Glomerular filtration rate (creatinine); LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg18306943 chr3:40428807 ENTPD3 0.42 7.38 0.37 1.21e-12 Renal cell carcinoma; LIHC cis rs4147929 0.761 rs3752246 chr19:1056492 G/C cg05372495 chr19:1063624 ABCA7 -0.44 -6.12 -0.31 2.5e-9 Alzheimer's disease (late onset); LIHC cis rs9918079 0.560 rs4698409 chr4:15659766 G/A cg21123203 chr4:15471301 CC2D2A -0.44 -7.06 -0.36 9.26e-12 Obesity-related traits; LIHC trans rs1945213 0.694 rs67394518 chr11:55855303 G/A cg03929089 chr4:120376271 NA 0.53 6.66 0.34 1.09e-10 Acute lymphoblastic leukemia (childhood); LIHC cis rs6708331 0.517 rs11692018 chr2:70369154 A/C cg01613454 chr2:70366299 NA 0.38 6.21 0.32 1.54e-9 Obesity-related traits; LIHC cis rs11864453 0.713 rs8051882 chr16:72142072 A/G cg01557791 chr16:72042693 DHODH 0.53 8.56 0.42 3.96e-16 Fibrinogen levels; LIHC cis rs12744310 1.000 rs12035913 chr1:41757057 A/G cg03962019 chr1:41807865 NA -0.36 -5.95 -0.31 6.74e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7487075 0.619 rs12824565 chr12:46834693 A/G cg23829395 chr12:46796953 NA 0.35 6.19 0.32 1.76e-9 Itch intensity from mosquito bite; LIHC cis rs875971 1.000 rs11974264 chr7:65647582 C/G cg11764359 chr7:65958608 NA -0.89 -15.52 -0.64 1.66e-41 Aortic root size; LIHC cis rs7412746 0.621 rs72704656 chr1:150828307 A/G cg17724175 chr1:150552817 MCL1 0.46 8.8 0.43 6.95e-17 Melanoma; LIHC cis rs11864453 0.713 rs7190995 chr16:72124157 A/G cg16558253 chr16:72132732 DHX38 -0.51 -8.1 -0.4 9.86e-15 Fibrinogen levels; LIHC cis rs4974559 0.501 rs1250093 chr4:1240911 G/A cg02980000 chr4:1222292 CTBP1 -0.85 -6.45 -0.33 3.86e-10 Systolic blood pressure; LIHC cis rs7772486 0.738 rs2246334 chr6:146183635 G/A cg13319975 chr6:146136371 FBXO30 -0.39 -6.38 -0.33 5.79e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 1.000 rs7599132 chr2:26279810 A/T cg27170947 chr2:26402098 FAM59B 0.66 8.24 0.41 3.75e-15 Gut microbiome composition (summer); LIHC cis rs2549003 0.870 rs10053046 chr5:131821558 A/G cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs7772486 0.764 rs7745696 chr6:146162829 T/C cg23711669 chr6:146136114 FBXO30 0.64 11.61 0.53 1.71e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 1.000 rs2009319 chr1:67481070 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.95 16.12 0.66 6.69e-44 Lymphocyte percentage of white cells; LIHC cis rs9322817 0.593 rs9404579 chr6:105229807 T/C cg02098413 chr6:105308735 HACE1 -0.42 -7.7 -0.38 1.46e-13 Thyroid stimulating hormone; LIHC cis rs8016982 0.632 rs4899786 chr14:81643800 G/T cg01989461 chr14:81687754 GTF2A1 -0.45 -7.33 -0.37 1.66e-12 Schizophrenia; LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg25072359 chr17:41440525 NA 0.37 5.89 0.3 9.21e-9 Menopause (age at onset); LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg20308189 chr12:122261415 SETD1B 0.46 6.5 0.33 2.9e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs6088590 0.687 rs6088582 chr20:33286798 G/A cg08999081 chr20:33150536 PIGU 0.59 10.65 0.5 4.66e-23 Coronary artery disease; LIHC cis rs6540556 0.769 rs9430017 chr1:209925058 C/T cg05527609 chr1:210001259 C1orf107 -0.69 -9.93 -0.47 1.43e-20 Red blood cell count; LIHC trans rs8002861 0.870 rs2121030 chr13:44444574 C/T cg17145862 chr1:211918768 LPGAT1 -0.6 -11.15 -0.52 7.67e-25 Leprosy; LIHC cis rs7772486 0.840 rs2474355 chr6:146312540 C/G cg23711669 chr6:146136114 FBXO30 0.66 11.34 0.52 1.57e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs3741798 1.000 rs61922047 chr12:12496471 C/A cg08615371 chr12:12503544 MANSC1 0.9 7.3 0.37 1.98e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs787274 1.000 rs787276 chr9:115551891 T/C cg13803584 chr9:115635662 SNX30 -0.6 -6.68 -0.34 9.69e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1046896 0.731 rs8067667 chr17:80785875 A/G cg02398342 chr17:80708632 TBCD;FN3K 0.41 6.16 0.32 2e-9 Glycated hemoglobin levels; LIHC cis rs2073300 0.609 rs6137950 chr20:23418722 T/A cg12062639 chr20:23401060 NAPB 1.04 13.41 0.59 2.97e-33 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7909074 1.000 rs6593447 chr10:45400235 G/A cg04218760 chr10:45406644 TMEM72 -0.23 -7.37 -0.37 1.34e-12 Mean corpuscular volume; LIHC cis rs6690583 0.623 rs12037219 chr1:85505951 G/A cg22153463 chr1:85462885 MCOLN2 0.49 5.87 0.3 1.03e-8 Serum sulfate level; LIHC cis rs25645 0.502 rs1007654 chr17:38111354 A/G cg17467752 chr17:38218738 THRA 0.4 5.81 0.3 1.42e-8 Myeloid white cell count; LIHC cis rs2033711 0.870 rs4801270 chr19:58932762 C/A cg13877915 chr19:58951672 ZNF132 0.57 8.87 0.43 4.18e-17 Uric acid clearance; LIHC cis rs11758351 0.660 rs11753131 chr6:26219384 G/A cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs9790314 1.000 rs9846756 chr3:160983809 A/C cg03342759 chr3:160939853 NMD3 -0.73 -8.81 -0.43 6.18e-17 Morning vs. evening chronotype; LIHC cis rs12478296 1.000 rs12469535 chr2:243044147 G/A cg06360820 chr2:242988706 NA -0.84 -12.02 -0.55 5.15e-28 Obesity-related traits; LIHC cis rs17376456 0.569 rs6881815 chr5:93105666 A/G cg25358565 chr5:93447407 FAM172A 0.8 7.68 0.38 1.63e-13 Diabetic retinopathy; LIHC cis rs10256972 0.626 rs62433138 chr7:1050877 T/C cg04025307 chr7:1156635 C7orf50 0.38 6.04 0.31 4.12e-9 Longevity;Endometriosis; LIHC cis rs875971 1.000 rs1565531 chr7:65663113 T/A cg18876405 chr7:65276391 NA -0.38 -6.88 -0.35 2.82e-11 Aortic root size; LIHC cis rs1801251 0.727 rs283482 chr2:233646920 A/T cg08000102 chr2:233561755 GIGYF2 0.75 12.28 0.55 5.72e-29 Coronary artery disease; LIHC trans rs3176789 0.647 rs10772127 chr12:9921790 T/C cg18988856 chr7:99425577 CYP3A43 0.19 6.16 0.32 2.09e-9 Lymphocyte percentage of white cells;Neutrophil percentage of white cells; LIHC cis rs875971 0.862 rs801204 chr7:66022921 T/C cg18252515 chr7:66147081 NA 0.45 6.59 0.34 1.62e-10 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17035366 chr12:40499623 SLC2A13 0.44 6.22 0.32 1.42e-9 Lung function (FEV1/FVC); LIHC cis rs7927592 0.956 rs10896348 chr11:68357368 T/C cg01657329 chr11:68192670 LRP5 -0.48 -6.4 -0.33 5.14e-10 Total body bone mineral density; LIHC trans rs2727020 0.521 rs11040408 chr11:49534880 A/T cg18944383 chr4:111397179 ENPEP -0.34 -7.81 -0.39 6.9e-14 Coronary artery disease; LIHC cis rs8072100 0.840 rs2136751 chr17:45456093 A/G cg25173405 chr17:45401733 C17orf57 -0.43 -5.94 -0.31 6.92e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18273408 chr1:11115091 SRM 0.42 6.39 0.33 5.57e-10 Longevity; LIHC cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg02290350 chr8:58132656 NA 0.4 8.54 0.42 4.47e-16 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg02187348 chr16:89574699 SPG7 0.61 9.53 0.46 2.98e-19 Multiple myeloma (IgH translocation); LIHC cis rs151997 0.962 rs39955 chr5:50187501 C/A cg06027927 chr5:50259733 NA 0.56 7.63 0.38 2.37e-13 Callous-unemotional behaviour; LIHC cis rs36051895 0.603 rs10123980 chr9:5130363 T/C cg02405213 chr9:5042618 JAK2 -0.65 -11.12 -0.52 9.75e-25 Pediatric autoimmune diseases; LIHC cis rs5770917 1.000 rs3180872 chr22:51017394 G/C cg24363820 chr22:51016703 CPT1B;CHKB-CPT1B -0.52 -6.97 -0.35 1.63e-11 Narcolepsy; LIHC cis rs427394 0.582 rs4701751 chr5:6704137 C/T cg10857441 chr5:6722123 POLS -0.37 -6.25 -0.32 1.21e-9 Menopause (age at onset); LIHC cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg11890956 chr21:40555474 PSMG1 0.58 9.42 0.45 7.03e-19 Cognitive function; LIHC cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg13397359 chr6:42928475 GNMT 0.64 9.37 0.45 9.86e-19 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9457247 1.000 rs10946199 chr6:167404492 G/A cg23791538 chr6:167370224 RNASET2 -0.65 -11.12 -0.52 9.6e-25 Crohn's disease; LIHC cis rs738321 0.701 rs2413506 chr22:38593128 T/C cg25457927 chr22:38595422 NA -0.39 -9.19 -0.44 4.05e-18 Breast cancer; LIHC cis rs7666738 0.830 rs1456208 chr4:98678563 C/T cg05340658 chr4:99064831 C4orf37 0.62 10.9 0.51 5.92e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18692276 chr12:57023408 BAZ2A 0.46 6.81 0.35 4.47e-11 Lung function (FEV1/FVC); LIHC cis rs2228479 0.850 rs11649162 chr16:89807131 C/A cg04013166 chr16:89971882 TCF25 0.49 6.07 0.31 3.31e-9 Skin colour saturation; LIHC trans rs62103177 0.810 rs62103187 chr18:77627633 G/C cg05926928 chr17:57297772 GDPD1 1.11 11.42 0.53 8.64e-26 Opioid sensitivity; LIHC cis rs59698941 0.765 rs12163971 chr5:132226669 C/A cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs9814567 1.000 rs6439487 chr3:134260860 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs17685 0.587 rs1623759 chr7:75724679 A/T cg19862616 chr7:65841803 NCRNA00174 0.92 18.56 0.71 1.05e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs5758511 0.680 rs1107553 chr22:42667473 A/G cg00645731 chr22:42541494 CYP2D7P1 0.5 8.02 0.4 1.71e-14 Birth weight; LIHC cis rs9303401 0.659 rs62083368 chr17:56878062 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.19 0.55 1.22e-28 Cognitive test performance; LIHC cis rs708547 0.647 rs1713982 chr4:57881715 G/A cg16868167 chr4:57843880 C4orf14;POLR2B 0.46 6.75 0.34 6.36e-11 Response to bleomycin (chromatid breaks); LIHC cis rs34779708 0.931 rs4934719 chr10:35376769 T/C cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10744422 1.000 rs897385 chr12:123341297 A/G cg25930673 chr12:123319894 HIP1R -0.96 -12.76 -0.57 9.14e-31 Schizophrenia; LIHC cis rs951366 0.789 rs823110 chr1:205701078 G/C cg14893161 chr1:205819251 PM20D1 0.68 9.89 0.47 1.95e-20 Menarche (age at onset); LIHC cis rs864643 1.000 rs1708056 chr3:39573153 C/A cg05136238 chr3:39556330 MOBP 0.31 5.81 0.3 1.44e-8 Attention deficit hyperactivity disorder; LIHC cis rs7044106 0.537 rs4434680 chr9:123489688 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.03 0.48 6.32e-21 Hip circumference adjusted for BMI; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04576684 chr19:17414284 ABHD8 0.48 6.57 0.33 1.91e-10 Lung function (FEV1/FVC); LIHC cis rs4700695 0.925 rs6878011 chr5:65392465 G/A cg21114390 chr5:65439923 SFRS12 -0.46 -6.03 -0.31 4.18e-9 Facial morphology (factor 19); LIHC cis rs4900538 0.821 rs8016191 chr14:102825340 G/A cg18135206 chr14:102964638 TECPR2 -0.71 -11.0 -0.51 2.71e-24 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC trans rs2832191 0.740 rs2832175 chr21:30475606 A/G cg14791747 chr16:20752902 THUMPD1 0.49 7.11 0.36 6.94e-12 Dental caries; LIHC cis rs1707322 1.000 rs1588663 chr1:46548825 G/A cg06784218 chr1:46089804 CCDC17 -0.37 -6.74 -0.34 6.8e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg18404041 chr3:52824283 ITIH1 -0.56 -9.25 -0.45 2.48e-18 Bipolar disorder; LIHC cis rs7552404 1.000 rs12126607 chr1:76217097 G/A cg22875332 chr1:76189707 ACADM 0.49 7.29 0.37 2.2e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs77861329 1.000 rs164638 chr3:52207886 T/G cg08692210 chr3:52188851 WDR51A 0.84 8.02 0.4 1.74e-14 Macrophage inflammatory protein 1b levels; LIHC cis rs3806933 0.522 rs11241095 chr5:110439509 A/G cg04022379 chr5:110408740 TSLP 0.57 9.24 0.45 2.78e-18 Eosinophilic esophagitis; LIHC cis rs7075426 0.716 rs10887610 chr10:88207000 C/T cg07322936 chr10:88137208 NA -0.46 -6.2 -0.32 1.61e-9 Migraine without aura; LIHC cis rs4423214 0.918 rs11233789 chr11:71181085 A/G cg05163923 chr11:71159392 DHCR7 0.82 12.46 0.56 1.24e-29 Vitamin D levels; LIHC cis rs921968 0.643 rs1850169 chr2:219487299 A/T cg02985541 chr2:219472218 PLCD4 0.43 7.88 0.39 4.28e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs17253792 0.822 rs76472022 chr14:56053660 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.15e-10 Putamen volume; LIHC trans rs61931739 0.517 rs860950 chr12:34104376 C/G cg26384229 chr12:38710491 ALG10B 0.49 6.9 0.35 2.55e-11 Morning vs. evening chronotype; LIHC cis rs60871478 1.000 rs34761279 chr7:794471 A/G cg11064039 chr7:766100 PRKAR1B;HEATR2 0.51 5.77 0.3 1.74e-8 Cerebrospinal P-tau181p levels; LIHC cis rs1008375 1.000 rs10027755 chr4:17615954 G/C cg16339924 chr4:17578868 LAP3 0.43 5.99 0.31 5.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs918629 0.567 rs11741590 chr5:95241127 A/G cg10483112 chr5:95245456 ELL2 0.38 7.05 0.36 1e-11 IgG glycosylation; LIHC trans rs11098499 0.697 rs10020027 chr4:120381879 G/C cg25214090 chr10:38739885 LOC399744 0.59 9.71 0.46 7.58e-20 Corneal astigmatism; LIHC cis rs6500637 0.558 rs11076856 chr16:4949815 A/G cg08329684 chr16:4932620 PPL -0.38 -6.75 -0.34 6.51e-11 Cancer; LIHC cis rs13108904 0.901 rs4974594 chr4:1300480 C/T cg20887711 chr4:1340912 KIAA1530 -0.42 -6.3 -0.32 9.06e-10 Obesity-related traits; LIHC cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -11.07 -0.51 1.5e-24 Platelet count; LIHC cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg12756686 chr19:29218302 NA 0.44 6.83 0.35 3.94e-11 Methadone dose in opioid dependence; LIHC cis rs9916302 0.904 rs4794807 chr17:37531718 T/A cg00129232 chr17:37814104 STARD3 0.4 6.52 0.33 2.59e-10 Glomerular filtration rate (creatinine); LIHC cis rs11792861 0.781 rs11793272 chr9:111762102 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 8.91 0.43 3.19e-17 Menarche (age at onset); LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg22528358 chr1:107598549 PRMT6 0.64 10.2 0.48 1.7e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs5758511 0.680 rs5758692 chr22:42669029 T/A cg00645731 chr22:42541494 CYP2D7P1 0.52 7.93 0.39 3.17e-14 Birth weight; LIHC cis rs6089829 0.962 rs11086151 chr20:61664644 C/T cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs6545883 0.894 rs2121661 chr2:61561658 A/G cg14146966 chr2:61757674 XPO1 -0.44 -7.38 -0.37 1.23e-12 Tuberculosis; LIHC cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg04546413 chr19:29218101 NA 0.54 10.48 0.49 1.77e-22 Methadone dose in opioid dependence; LIHC cis rs561341 0.602 rs114562703 chr17:30233899 G/T cg13647721 chr17:30228624 UTP6 0.75 8.24 0.41 3.59e-15 Hip circumference adjusted for BMI; LIHC cis rs1008375 1.000 rs11737138 chr4:17657986 G/A cg16339924 chr4:17578868 LAP3 0.45 6.35 0.32 6.94e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9640161 0.789 rs1464751 chr7:150021282 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.51 -8.85 -0.43 4.67e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs11673344 0.704 rs544543 chr19:37430823 A/G cg27390819 chr19:37464633 NA -0.5 -6.01 -0.31 4.88e-9 Obesity-related traits; LIHC cis rs5769765 0.819 rs9616379 chr22:50312035 C/T cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs1355223 0.583 rs2915179 chr11:34871943 C/T cg11058730 chr11:34937778 PDHX;APIP 0.74 12.63 0.56 2.74e-30 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7520050 0.966 rs6700597 chr1:46284246 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.98 0.31 5.65e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10857712 0.687 rs11101742 chr10:135224372 C/G cg01444801 chr10:135216882 MTG1 -0.51 -8.1 -0.4 9.8e-15 Systemic lupus erythematosus; LIHC cis rs4555082 0.830 rs2816614 chr14:105727359 C/T cg13114125 chr14:105738426 BRF1 -0.72 -9.35 -0.45 1.21e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg16606324 chr3:10149918 C3orf24 0.54 5.81 0.3 1.4e-8 Alzheimer's disease; LIHC cis rs798554 0.757 rs1182188 chr7:2869985 T/C cg13628971 chr7:2884303 GNA12 0.5 6.94 0.35 1.94e-11 Height; LIHC cis rs6456156 0.565 rs12525345 chr6:167478875 T/C cg07741184 chr6:167504864 NA 0.29 6.84 0.35 3.57e-11 Primary biliary cholangitis; LIHC cis rs769267 0.930 rs1047361 chr19:19606634 G/A cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.99 0.31 5.2e-9 Tonsillectomy; LIHC cis rs10791097 0.694 rs12361892 chr11:130744490 T/G cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs4753788 0.511 rs12224337 chr11:107140077 G/A cg07207367 chr16:67978216 SLC12A4;LCAT 0.32 6.1 0.31 2.81e-9 Coronary artery disease; LIHC cis rs1005277 0.579 rs1740735 chr10:38497777 A/C cg25427524 chr10:38739819 LOC399744 -0.75 -15.03 -0.63 1.49e-39 Extrinsic epigenetic age acceleration; LIHC cis rs11585357 0.895 rs4625336 chr1:17630964 G/T cg08277548 chr1:17600880 PADI3 -0.53 -5.87 -0.3 1.03e-8 Hair shape; LIHC cis rs4843747 0.671 rs8053377 chr16:88106465 A/G cg06050784 chr16:88016603 BANP 0.35 6.42 0.33 4.64e-10 Menopause (age at onset); LIHC cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg00091569 chr3:40428383 ENTPD3 0.4 6.77 0.34 5.55e-11 Renal cell carcinoma; LIHC cis rs1494373 0.543 rs11809755 chr1:220932051 G/A cg06786860 chr1:220876396 NA -0.38 -5.73 -0.3 2.26e-8 Response to antipsychotic therapy (extrapyramidal side effects); LIHC cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg10755058 chr3:40428713 ENTPD3 0.36 6.09 0.31 2.95e-9 Renal cell carcinoma; LIHC cis rs950169 0.922 rs12915832 chr15:85111457 C/T cg17507749 chr15:85114479 UBE2QP1 0.75 8.68 0.42 1.63e-16 Schizophrenia; LIHC trans rs9956878 0.555 rs8085188 chr18:73544676 A/G cg10368533 chr12:22778127 ETNK1 -0.42 -6.32 -0.32 8.4e-10 Obesity-related traits; LIHC cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 10.28 0.49 8.93e-22 Platelet count; LIHC cis rs1577917 0.958 rs12212480 chr6:86458777 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.14 -0.52 8.53e-25 Response to antipsychotic treatment; LIHC cis rs7208859 0.623 rs9915546 chr17:29132144 G/T cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4388979 0.929 rs3742028 chr12:109491468 G/A cg03220751 chr12:109490328 USP30 0.87 12.99 0.57 1.28e-31 Plateletcrit;Platelet count; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg25270632 chr7:43751042 C7orf44 0.35 6.64 0.34 1.22e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs600806 0.713 rs10745305 chr1:110012148 A/G cg11161837 chr1:110010384 SYPL2 0.48 6.53 0.33 2.35e-10 Intelligence (multi-trait analysis); LIHC cis rs9837602 0.529 rs793495 chr3:99507934 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.83 0.3 1.26e-8 Breast cancer; LIHC cis rs11098499 1.000 rs35643470 chr4:120184948 T/C cg09307838 chr4:120376055 NA 0.74 10.87 0.51 7.72e-24 Corneal astigmatism; LIHC cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg03264133 chr6:25882463 NA -0.59 -8.36 -0.41 1.65e-15 Blood metabolite levels; LIHC trans rs61931739 0.534 rs11052973 chr12:34029708 A/G cg26384229 chr12:38710491 ALG10B 0.52 7.17 0.36 4.69e-12 Morning vs. evening chronotype; LIHC cis rs7937682 0.632 rs12785809 chr11:111776055 T/A cg09085632 chr11:111637200 PPP2R1B 0.93 13.78 0.6 1.2e-34 Primary sclerosing cholangitis; LIHC cis rs4742903 0.935 rs975253 chr9:106928260 G/C cg14250997 chr9:106856677 SMC2 0.36 6.02 0.31 4.43e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg09455208 chr3:40491958 NA 0.34 6.8 0.35 4.66e-11 Renal cell carcinoma; LIHC cis rs12701220 0.655 rs9638973 chr7:1133678 A/G cg04025307 chr7:1156635 C7orf50 0.56 7.53 0.38 4.63e-13 Bronchopulmonary dysplasia; LIHC cis rs763121 0.657 rs5995603 chr22:39040733 G/A cg06022373 chr22:39101656 GTPBP1 0.63 10.3 0.49 7.8e-22 Menopause (age at onset); LIHC cis rs9457247 1.000 rs408040 chr6:167398903 A/T cg12798992 chr6:167411361 FGFR1OP 0.6 10.15 0.48 2.49e-21 Crohn's disease; LIHC cis rs920590 0.758 rs62496731 chr8:19659543 C/G cg03894339 chr8:19674705 INTS10 0.63 10.06 0.48 5e-21 Acute lymphoblastic leukemia (childhood); LIHC cis rs10089 1.000 rs73337363 chr5:127483597 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.74 0.34 6.93e-11 Ileal carcinoids; LIHC cis rs4788570 0.697 rs2334877 chr16:71833332 C/T cg06353428 chr16:71660113 MARVELD3 1.29 13.99 0.6 1.69e-35 Intelligence (multi-trait analysis); LIHC cis rs2303759 1.000 rs2303759 chr19:49869051 T/G cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 9.01 0.44 1.5e-17 Multiple sclerosis; LIHC cis rs7659604 0.539 rs1507995 chr4:122748308 G/A cg20573242 chr4:122745356 CCNA2 0.52 7.66 0.38 1.98e-13 Type 2 diabetes; LIHC cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg23149560 chr2:74406255 MOBKL1B 0.4 5.86 0.3 1.11e-8 Gestational age at birth (maternal effect); LIHC cis rs10744422 1.000 rs3817094 chr12:123332032 T/C cg18912006 chr12:123335444 HIP1R -0.63 -7.64 -0.38 2.14e-13 Schizophrenia; LIHC cis rs12791968 1.000 rs11038237 chr11:45001880 C/T cg11846598 chr11:44996168 LOC221122 -0.44 -7.91 -0.39 3.56e-14 Inhibitory control; LIHC cis rs7927771 0.839 rs7124681 chr11:47529947 C/A cg20135002 chr11:47629003 NA -0.52 -9.14 -0.44 5.78e-18 Subjective well-being; LIHC cis rs6445975 0.667 rs3773004 chr3:58269451 A/G cg23715586 chr3:58305044 RPP14 -0.38 -6.32 -0.32 8.17e-10 Systemic lupus erythematosus; LIHC cis rs2204008 0.837 rs8189467 chr12:38241956 T/C cg13010199 chr12:38710504 ALG10B 0.49 5.9 0.3 8.58e-9 Bladder cancer; LIHC cis rs208515 0.525 rs12193034 chr6:66677866 C/T cg07460842 chr6:66804631 NA 0.77 8.85 0.43 4.91e-17 Exhaled nitric oxide levels; LIHC trans rs13113518 0.812 rs2035691 chr4:56395953 C/T cg15358633 chr12:38710606 ALG10B 0.43 6.13 0.31 2.42e-9 Height; LIHC cis rs7520050 0.778 rs2088102 chr1:46032974 T/C cg24296786 chr1:45957014 TESK2 0.44 6.43 0.33 4.18e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7089973 0.624 rs11196930 chr10:116583596 C/T cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs769267 0.930 rs1054930 chr19:19648346 G/C cg15052019 chr19:19431593 KIAA0892;SF4 0.45 6.1 0.31 2.84e-9 Tonsillectomy; LIHC cis rs12413816 0.517 rs4750400 chr10:13765923 A/G cg16485048 chr10:13749193 FRMD4A 0.43 5.98 0.31 5.71e-9 Red cell distribution width; LIHC cis rs4728302 0.838 rs2042453 chr7:133580730 G/A cg10665199 chr7:133106180 EXOC4 0.34 6.01 0.31 4.63e-9 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs4474465 0.850 rs7122676 chr11:78268525 A/G cg02023728 chr11:77925099 USP35 -0.34 -5.96 -0.31 6.37e-9 Alzheimer's disease (survival time); LIHC cis rs67478160 0.643 rs4900594 chr14:104251006 C/T cg08213375 chr14:104286397 PPP1R13B 0.65 12.42 0.56 1.74e-29 Schizophrenia; LIHC cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.35 0.45 1.18e-18 Intelligence (multi-trait analysis); LIHC cis rs17125944 0.615 rs12589020 chr14:53312002 C/T cg00686598 chr14:53173677 PSMC6 0.9 10.38 0.49 4.11e-22 Alzheimer's disease (late onset); LIHC trans rs11638815 0.626 rs4779041 chr15:83337059 G/A cg18393722 chr15:85113863 UBE2QP1 0.36 6.08 0.31 3.16e-9 Lipoprotein-associated phospholipase A2 activity change in response to statin therapy; LIHC cis rs1371867 0.875 rs1371868 chr8:101330267 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -9.06 -0.44 1.01e-17 Atrioventricular conduction; LIHC trans rs12478296 0.892 rs11893879 chr2:243010411 G/A cg01596870 chr19:55963115 NA -0.68 -9.79 -0.47 3.97e-20 Obesity-related traits; LIHC cis rs67478160 0.619 rs28698555 chr14:104316486 C/A cg01849466 chr14:104193079 ZFYVE21 0.48 7.59 0.38 3.01e-13 Schizophrenia; LIHC cis rs2839186 0.967 rs2839191 chr21:47695395 C/G cg12016809 chr21:47604291 C21orf56 0.4 5.87 0.3 1.05e-8 Testicular germ cell tumor; LIHC cis rs2806561 0.754 rs750354 chr1:23297406 T/C cg19743168 chr1:23544995 NA -0.37 -6.85 -0.35 3.36e-11 Height; LIHC cis rs1552244 1.000 rs7626117 chr3:10140671 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.77 10.2 0.48 1.63e-21 Alzheimer's disease; LIHC cis rs2282802 0.685 rs11748023 chr5:139558584 C/T cg26211634 chr5:139558579 C5orf32 -0.38 -5.92 -0.3 7.76e-9 Intelligence (multi-trait analysis); LIHC cis rs763121 0.853 rs10135 chr22:39082174 C/T cg06022373 chr22:39101656 GTPBP1 -0.7 -14.05 -0.6 1.03e-35 Menopause (age at onset); LIHC cis rs2455799 0.573 rs62243672 chr3:15937200 C/T cg12698662 chr3:15914712 MIR563 -0.37 -6.9 -0.35 2.48e-11 Mean platelet volume; LIHC cis rs4819052 1.000 rs2297285 chr21:46705621 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.71 -8.98 -0.44 1.88e-17 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9411298 0.630 rs9411299 chr9:139938793 C/G cg14024893 chr9:139943146 ENTPD2 -0.65 -10.04 -0.48 5.69e-21 Monocyte percentage of white cells; LIHC cis rs9810089 0.758 rs12492510 chr3:136151631 G/T cg21827317 chr3:136751795 NA 0.44 5.88 0.3 9.87e-9 Gestational age at birth (child effect); LIHC cis rs6665290 0.935 rs1929864 chr1:227195500 T/G cg10327440 chr1:227177885 CDC42BPA -1.18 -25.93 -0.81 1e-82 Myeloid white cell count; LIHC cis rs7961581 0.748 rs1705255 chr12:71601847 C/T cg05756094 chr12:71608604 NA 0.42 6.85 0.35 3.51e-11 Type 2 diabetes; LIHC cis rs2153535 0.580 rs9405391 chr6:8466548 C/T cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.09e-14 Motion sickness; LIHC cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.8 0.3 1.51e-8 Bipolar disorder; LIHC cis rs9733 0.519 rs12095002 chr1:150649249 G/A cg17724175 chr1:150552817 MCL1 0.48 9.56 0.46 2.48e-19 Tonsillectomy; LIHC cis rs7617773 0.817 rs11707606 chr3:48237087 A/C cg11946769 chr3:48343235 NME6 0.9 11.19 0.52 5.8e-25 Coronary artery disease; LIHC cis rs35417517 1 rs35417517 chr7:91772730 CG/C cg17063962 chr7:91808500 NA 1.06 22.62 0.77 6.65e-70 Breast cancer; LIHC cis rs9814567 1.000 rs7433991 chr3:134312292 A/T cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.89 -0.3 9.45e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs1728785 1.000 rs1170429 chr16:68604126 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.27 0.32 1.12e-9 Ulcerative colitis; LIHC cis rs9303280 0.936 rs12950209 chr17:38049102 T/C cg11212589 chr17:38028394 ZPBP2 0.37 7.62 0.38 2.46e-13 Self-reported allergy; LIHC trans rs6952808 0.723 rs60432611 chr7:2029629 G/C cg04565464 chr8:145669602 NFKBIL2 0.4 6.69 0.34 9.34e-11 Bipolar disorder and schizophrenia; LIHC cis rs1801251 1.000 rs35085837 chr2:233624363 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.5 0.53 4.14e-26 Coronary artery disease; LIHC cis rs6061231 0.916 rs58488796 chr20:60949050 G/C cg24112000 chr20:60950667 NA -0.6 -8.34 -0.41 1.9e-15 Colorectal cancer; LIHC cis rs2204008 0.774 rs11615665 chr12:38328162 T/A cg26384229 chr12:38710491 ALG10B 0.61 8.16 0.4 6.41e-15 Bladder cancer; LIHC cis rs1552244 0.882 rs13099136 chr3:10031431 G/A cg13047869 chr3:10149882 C3orf24 0.42 5.9 0.3 8.71e-9 Alzheimer's disease; LIHC trans rs837841 0.864 rs1660903 chr2:130046679 C/G cg17644311 chr12:94854007 CCDC41;LOC144486 0.39 6.26 0.32 1.12e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel); LIHC cis rs8017423 0.935 rs7144070 chr14:90753047 T/C cg14092571 chr14:90743983 NA -0.42 -6.54 -0.33 2.27e-10 Mortality in heart failure; LIHC cis rs875971 0.522 rs709604 chr7:65497434 A/G cg18876405 chr7:65276391 NA -0.55 -9.27 -0.45 2.15e-18 Aortic root size; LIHC cis rs4819052 0.851 rs28676615 chr21:46676576 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.91 0.39 3.69e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs739401 0.611 rs10833048 chr11:3020040 A/G cg08508325 chr11:3079039 CARS -0.32 -6.77 -0.34 5.7e-11 Longevity; LIHC cis rs5753618 0.561 rs4820043 chr22:31647094 A/G cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Colorectal cancer; LIHC cis rs9905704 0.647 rs2108435 chr17:57102133 T/C cg05425664 chr17:57184151 TRIM37 0.43 6.13 0.31 2.48e-9 Testicular germ cell tumor; LIHC cis rs3096299 0.967 rs2965935 chr16:89481274 C/T cg00750074 chr16:89608354 SPG7 0.4 6.21 0.32 1.51e-9 Multiple myeloma (IgH translocation); LIHC cis rs1182196 0.502 rs757786 chr7:2836019 C/T cg19717773 chr7:2847554 GNA12 -0.46 -9.06 -0.44 1.02e-17 Plateletcrit; LIHC cis rs600806 0.850 rs4120621 chr1:109949008 A/G cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.13 -0.36 6.2e-12 Intelligence (multi-trait analysis); LIHC cis rs1256061 0.603 rs1256045 chr14:64729760 A/C cg23250157 chr14:64679961 SYNE2 0.4 6.03 0.31 4.19e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs3981351 0.797 rs12766891 chr10:115460714 G/A cg24846397 chr10:115438155 CASP7 -0.46 -7.11 -0.36 6.99e-12 Obesity-related traits; LIHC cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg25364880 chr3:44379878 C3orf23 0.48 6.93 0.35 2.17e-11 Depressive symptoms; LIHC cis rs7635838 0.587 rs1992910 chr3:11311942 C/T cg00170343 chr3:11313890 ATG7 0.62 10.53 0.49 1.21e-22 HDL cholesterol; LIHC cis rs734999 0.545 rs4074789 chr1:2537464 A/G cg18854424 chr1:2615690 NA 0.33 7.38 0.37 1.23e-12 Ulcerative colitis; LIHC cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg13395646 chr4:1353034 KIAA1530 -0.59 -8.73 -0.43 1.12e-16 Obesity-related traits; LIHC cis rs2303745 0.544 rs6512180 chr19:17399153 C/T cg10664184 chr19:17420304 DDA1 0.47 5.93 0.31 7.61e-9 Systemic lupus erythematosus; LIHC cis rs35306767 0.855 rs61830931 chr10:932497 T/C cg26597838 chr10:835615 NA 1.46 16.66 0.67 4.99e-46 Eosinophil percentage of granulocytes; LIHC cis rs11792861 0.591 rs2275641 chr9:111696389 G/C cg05043794 chr9:111880884 C9orf5 -0.23 -5.78 -0.3 1.7e-8 Menarche (age at onset); LIHC cis rs9467773 0.967 rs9461267 chr6:26525455 T/G cg09904177 chr6:26538194 HMGN4 0.67 14.0 0.6 1.66e-35 Intelligence (multi-trait analysis); LIHC cis rs2836950 0.520 rs8133928 chr21:40689963 G/A cg11890956 chr21:40555474 PSMG1 -0.42 -6.74 -0.34 6.64e-11 Menarche (age at onset); LIHC cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg09323728 chr8:95962352 TP53INP1 -0.3 -6.66 -0.34 1.12e-10 Type 2 diabetes; LIHC cis rs3790645 1.000 rs34062688 chr1:26887150 A/G cg23229016 chr1:26872525 RPS6KA1 0.23 5.77 0.3 1.8e-8 Glucose homeostasis traits; LIHC cis rs798554 0.724 rs798498 chr7:2795882 T/G cg04166393 chr7:2884313 GNA12 0.43 6.13 0.31 2.44e-9 Height; LIHC cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg16325326 chr1:53192061 ZYG11B -0.4 -6.78 -0.34 5.24e-11 Monocyte count; LIHC cis rs6430585 0.583 rs12475516 chr2:136560761 C/G cg25344623 chr2:136566232 LCT -0.38 -6.37 -0.33 6.24e-10 Corneal structure; LIHC cis rs9303401 0.659 rs56162835 chr17:56687315 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs2120019 1.000 rs2083731 chr15:75368538 A/C cg09165964 chr15:75287851 SCAMP5 -0.58 -9.29 -0.45 1.87e-18 Blood trace element (Zn levels); LIHC cis rs9916302 0.706 rs9890198 chr17:37457480 A/C cg07936489 chr17:37558343 FBXL20 0.85 12.2 0.55 1.1e-28 Glomerular filtration rate (creatinine); LIHC cis rs28595532 0.668 rs72670237 chr4:119320937 T/C cg21605333 chr4:119757512 SEC24D 0.94 7.27 0.37 2.54e-12 Cannabis dependence symptom count; LIHC cis rs250677 0.687 rs250671 chr5:148446523 T/C cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs11758351 1.000 rs2143347 chr6:26198494 C/T cg06951627 chr6:26196580 NA 0.51 5.77 0.3 1.78e-8 Gout;Renal underexcretion gout; LIHC cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg03264133 chr6:25882463 NA -0.64 -7.88 -0.39 4.46e-14 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.967 rs4493117 chr17:28489770 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.92 0.47 1.48e-20 Coffee consumption (cups per day); LIHC cis rs919433 0.713 rs10178946 chr2:198463090 G/T cg10820045 chr2:198174542 NA 0.48 7.67 0.38 1.75e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9583531 0.689 rs1061386 chr13:111373368 G/C cg24331049 chr13:111365604 ING1 0.79 13.02 0.58 9.37e-32 Coronary artery disease; LIHC cis rs2439831 1.000 rs561863 chr15:43761352 G/A cg15269541 chr15:43626905 ADAL -0.3 -5.89 -0.3 9.32e-9 Lung cancer in ever smokers; LIHC cis rs7829975 0.606 rs11776838 chr8:8794801 C/T cg06636001 chr8:8085503 FLJ10661 -0.39 -6.08 -0.31 3.17e-9 Mood instability; LIHC cis rs3106136 1.000 rs3106136 chr4:95153349 T/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.87 -0.39 4.77e-14 Capecitabine sensitivity; LIHC cis rs9309711 0.666 rs11127430 chr2:3485242 G/C cg10845886 chr2:3471009 TTC15 -0.43 -8.15 -0.4 6.92e-15 Neurofibrillary tangles; LIHC cis rs7408868 0.908 rs10416777 chr19:15276923 C/T cg09752223 chr19:15281200 NOTCH3 -0.37 -5.86 -0.3 1.07e-8 Pulse pressure; LIHC cis rs11625487 0.515 rs12434419 chr14:77855617 G/A cg20045696 chr14:77926864 AHSA1 -0.71 -8.66 -0.42 1.92e-16 Neutrophil percentage of white cells;Sum neutrophil eosinophil counts;Neutrophil count; LIHC cis rs1865721 1.000 rs72977888 chr18:73195250 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.6 -0.38 2.88e-13 Intelligence; LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.95 -0.31 6.55e-9 Total body bone mineral density; LIHC cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg21486233 chr12:29375141 FAR2 0.3 5.74 0.3 2.04e-8 QT interval; LIHC cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg06481639 chr22:41940642 POLR3H -0.67 -6.86 -0.35 3.2e-11 Vitiligo; LIHC cis rs2242116 0.760 rs4682845 chr3:46955404 G/C cg02527881 chr3:46936655 PTH1R -0.51 -10.68 -0.5 3.63e-23 Birth weight; LIHC cis rs743757 0.878 rs1467914 chr3:50523668 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.45 6.79 0.34 4.93e-11 Diastolic blood pressure; LIHC cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg08219700 chr8:58056026 NA 0.53 6.36 0.33 6.6e-10 Developmental language disorder (linguistic errors); LIHC cis rs727505 1.000 rs10246424 chr7:124494861 A/G cg23710748 chr7:124431027 NA -0.33 -5.82 -0.3 1.37e-8 Lewy body disease; LIHC cis rs4689592 0.503 rs10516184 chr4:7060959 C/T cg06697600 chr4:7070879 GRPEL1 -0.64 -9.65 -0.46 1.2e-19 Monocyte percentage of white cells; LIHC cis rs34779708 0.801 rs12242110 chr10:35535695 A/G cg03585969 chr10:35415529 CREM 0.85 12.75 0.57 9.97e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs5769765 0.646 rs9627789 chr22:50300562 A/G cg26441486 chr22:50317300 CRELD2 0.37 6.19 0.32 1.76e-9 Schizophrenia; LIHC cis rs2153535 0.580 rs718503 chr6:8527463 A/T cg23788917 chr6:8435910 SLC35B3 0.64 9.09 0.44 7.98e-18 Motion sickness; LIHC cis rs9733 0.596 rs6678013 chr1:150623285 T/G cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs7772486 0.840 rs854144 chr6:146360880 G/T cg23711669 chr6:146136114 FBXO30 -0.51 -8.11 -0.4 8.86e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.779 rs10016060 chr4:120298412 A/G cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs9916302 0.706 rs9908131 chr17:37520449 T/C cg07936489 chr17:37558343 FBXL20 0.86 12.19 0.55 1.29e-28 Glomerular filtration rate (creatinine); LIHC cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.5 0.46 3.82e-19 Bipolar disorder; LIHC cis rs11098499 0.955 rs1511018 chr4:120161580 G/T cg09307838 chr4:120376055 NA 0.74 10.91 0.51 5.39e-24 Corneal astigmatism; LIHC cis rs12188164 0.561 rs2251843 chr5:457955 C/T cg24955955 chr5:415729 AHRR -0.32 -6.52 -0.33 2.48e-10 Cystic fibrosis severity; LIHC cis rs6088590 1.000 rs2180276 chr20:33360785 T/A cg08999081 chr20:33150536 PIGU 0.37 5.77 0.3 1.78e-8 Coronary artery disease; LIHC cis rs6840360 1.000 rs6846114 chr4:152604558 A/G cg22705602 chr4:152727874 NA 0.3 6.16 0.32 1.99e-9 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.935 rs1883098 chr11:8890594 G/A cg12365402 chr11:9010492 NRIP3 -0.24 -6.17 -0.32 1.94e-9 Hemoglobin concentration; LIHC cis rs17826219 0.500 rs28452421 chr17:29083980 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 8.11e-15 Body mass index; LIHC cis rs4654899 0.758 rs6689852 chr1:21341051 T/C cg08539965 chr1:21396338 EIF4G3 0.33 5.87 0.3 1.04e-8 Superior frontal gyrus grey matter volume; LIHC cis rs8114671 0.562 rs1801310 chr20:33517014 A/G cg07148914 chr20:33460835 GGT7 0.66 10.13 0.48 2.83e-21 Height; LIHC cis rs9633740 0.773 rs7080009 chr10:82269461 T/C cg01528321 chr10:82214614 TSPAN14 0.93 11.43 0.53 7.91e-26 Post bronchodilator FEV1; LIHC cis rs10426930 0.816 rs2602727 chr19:5052107 G/A cg18473234 chr19:5097819 KDM4B -0.54 -7.0 -0.35 1.33e-11 Monocyte percentage of white cells; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.02 0.6 1.3e-35 Prudent dietary pattern; LIHC cis rs12478296 0.786 rs6721704 chr2:242994923 A/G cg18898632 chr2:242989856 NA -0.51 -7.27 -0.37 2.52e-12 Obesity-related traits; LIHC cis rs2625529 0.824 rs4238449 chr15:72421603 G/A cg16672083 chr15:72433130 SENP8 -0.31 -5.8 -0.3 1.51e-8 Red blood cell count; LIHC cis rs36051895 0.530 rs60768043 chr9:5224676 T/G cg02405213 chr9:5042618 JAK2 -0.62 -9.23 -0.45 2.93e-18 Pediatric autoimmune diseases; LIHC cis rs10089 1.000 rs883074 chr5:127445823 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.53 -6.78 -0.34 5.34e-11 Ileal carcinoids; LIHC cis rs4716602 0.596 rs10458244 chr7:156164285 C/T cg16983916 chr7:156159713 NA -0.33 -5.82 -0.3 1.38e-8 Anti-saccade response; LIHC cis rs17685 0.672 rs55807301 chr7:75807401 C/A cg16684958 chr7:75615977 POR 0.5 8.29 0.41 2.69e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35110281 0.627 rs1595167 chr21:44965874 T/G cg21573476 chr21:45109991 RRP1B -0.52 -9.68 -0.46 9.26e-20 Mean corpuscular volume; LIHC cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg00343986 chr7:65444356 GUSB 0.44 6.11 0.31 2.74e-9 Calcium levels; LIHC cis rs939574 1.000 rs908196 chr2:220088248 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.9 -9.95 -0.47 1.19e-20 Platelet distribution width; LIHC cis rs7552404 0.961 rs448710 chr1:76116554 T/C cg03433033 chr1:76189801 ACADM -0.69 -9.95 -0.47 1.23e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7923452 1.000 rs7923452 chr10:30751171 T/C cg25182066 chr10:30743637 MAP3K8 0.69 9.68 0.46 9.9e-20 Itch intensity from mosquito bite; LIHC cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs6840360 1.000 rs1864300 chr4:152663326 T/C cg22705602 chr4:152727874 NA -0.34 -7.24 -0.36 2.94e-12 Intelligence (multi-trait analysis); LIHC cis rs9549367 0.737 rs71446680 chr13:113894846 C/T cg00898013 chr13:113819073 PROZ -0.41 -7.23 -0.36 3.19e-12 Platelet distribution width; LIHC cis rs4803468 1.000 rs2569754 chr19:41936734 A/G cg14132834 chr19:41945861 ATP5SL -0.45 -6.74 -0.34 6.79e-11 Height; LIHC cis rs2073300 0.609 rs17757228 chr20:23351288 A/T cg16736954 chr20:23401023 NAPB 0.73 8.71 0.43 1.31e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs826838 0.684 rs12367400 chr12:38618673 G/T cg26384229 chr12:38710491 ALG10B 0.98 12.83 0.57 4.89e-31 Heart rate; LIHC cis rs1198430 0.639 rs685059 chr1:23783185 C/G cg19827787 chr1:23763612 ASAP3 0.28 6.09 0.31 2.99e-9 Total cholesterol levels; LIHC cis rs5769707 0.837 rs5769709 chr22:50021757 C/T cg01652190 chr22:50026171 C22orf34 -0.3 -6.88 -0.35 2.82e-11 Monocyte count;Monocyte percentage of white cells; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg24123311 chr19:48675164 NA 0.36 6.1 0.31 2.86e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs12594515 0.874 rs8032878 chr15:45998015 A/G cg01629716 chr15:45996671 NA 0.51 9.21 0.45 3.44e-18 Waist circumference;Weight; LIHC cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg20684491 chr1:25596433 NA 0.29 5.9 0.3 8.52e-9 Erythrocyte sedimentation rate; LIHC cis rs539514 0.513 rs7324353 chr13:76272283 A/C cg04757411 chr13:76259545 LMO7 -0.42 -7.03 -0.36 1.14e-11 Type 1 diabetes; LIHC cis rs2380220 0.576 rs4498363 chr6:96042338 A/C cg23517279 chr6:96025343 MANEA 0.57 5.83 0.3 1.25e-8 Behavioural disinhibition (generation interaction); LIHC cis rs17106184 0.892 rs60832780 chr1:51303714 T/C cg07174182 chr1:51127561 FAF1 -0.62 -6.62 -0.34 1.4e-10 Type 2 diabetes; LIHC cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg27572855 chr1:25598939 RHD -0.42 -9.35 -0.45 1.14e-18 Erythrocyte sedimentation rate; LIHC cis rs4713118 0.955 rs9468200 chr6:27683063 T/A cg20933634 chr6:27740509 NA 0.47 6.3 0.32 9.11e-10 Parkinson's disease; LIHC cis rs420259 0.636 rs34513 chr16:23671992 C/G cg05131483 chr16:23706242 ERN2 0.34 5.8 0.3 1.55e-8 Bipolar disorder; LIHC cis rs17376456 0.877 rs28539612 chr5:93499099 C/T cg25358565 chr5:93447407 FAM172A 1.11 10.2 0.48 1.69e-21 Diabetic retinopathy; LIHC cis rs6964587 1.000 rs7811873 chr7:91751120 G/A cg17063962 chr7:91808500 NA 1.02 19.53 0.73 1.39e-57 Breast cancer; LIHC trans rs5756813 0.661 rs6000898 chr22:38202399 T/C cg19894588 chr14:64061835 NA -0.68 -10.11 -0.48 3.29e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.55 7.33 0.37 1.7e-12 Osteoporosis; LIHC cis rs2273669 0.667 rs16822 chr6:109307710 G/A cg05315195 chr6:109294784 ARMC2 -0.52 -5.76 -0.3 1.85e-8 Prostate cancer; LIHC cis rs769267 0.929 rs2905424 chr19:19473445 T/C cg15052019 chr19:19431593 KIAA0892;SF4 -0.46 -6.48 -0.33 3.17e-10 Tonsillectomy; LIHC cis rs7617773 0.539 rs2017859 chr3:48382261 G/A cg11946769 chr3:48343235 NME6 0.61 7.52 0.38 4.92e-13 Coronary artery disease; LIHC cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg18404041 chr3:52824283 ITIH1 -0.57 -9.5 -0.46 3.88e-19 Bipolar disorder; LIHC cis rs34779708 0.931 rs10466072 chr10:35402756 C/T cg03585969 chr10:35415529 CREM 0.8 11.89 0.54 1.63e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7945705 0.738 rs11042067 chr11:8815453 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.39 -6.87 -0.35 3.09e-11 Hemoglobin concentration; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.73 0.39 1.23e-13 Prudent dietary pattern; LIHC cis rs7659604 0.521 rs4833235 chr4:122695136 C/A cg19671926 chr4:122722719 EXOSC9 0.56 8.51 0.42 5.44e-16 Type 2 diabetes; LIHC cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.93 8.33 0.41 2.03e-15 Platelet count; LIHC cis rs11122272 0.735 rs2808591 chr1:231523421 G/A cg06096015 chr1:231504339 EGLN1 0.5 9.27 0.45 2.08e-18 Hemoglobin concentration; LIHC cis rs1348850 0.914 rs3813259 chr2:178257214 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.88 14.27 0.61 1.44e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11788103 chr19:12833533 TNPO2 0.47 6.87 0.35 2.98e-11 Lung function (FEV1/FVC); LIHC cis rs4700695 0.764 rs37018 chr5:65366645 A/G cg21114390 chr5:65439923 SFRS12 0.46 5.98 0.31 5.57e-9 Facial morphology (factor 19); LIHC cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg10150615 chr22:24372951 LOC391322 0.43 5.73 0.3 2.19e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2858942 0.602 rs1211375 chr16:240280 G/T cg08400316 chr16:204221 HBZ -0.42 -6.94 -0.35 1.94e-11 Mean corpuscular hemoglobin; LIHC cis rs72829446 0.530 rs11869899 chr17:7407915 C/T cg02795151 chr17:7402630 POLR2A 0.55 6.39 0.33 5.45e-10 Androgen levels; LIHC cis rs2228479 0.717 rs9282682 chr16:89805794 A/G cg19635926 chr16:89946313 TCF25 0.46 5.92 0.31 7.66e-9 Skin colour saturation; LIHC cis rs2286503 0.839 rs4722188 chr7:22860211 C/G cg11367502 chr7:22862612 TOMM7 0.45 7.44 0.37 8.16e-13 Fibrinogen; LIHC cis rs9517313 0.707 rs9517298 chr13:99095003 C/T cg20487152 chr13:99095054 FARP1 -0.48 -8.25 -0.41 3.54e-15 Neuroticism; LIHC cis rs7107174 1.000 rs10899491 chr11:78106305 T/C cg02023728 chr11:77925099 USP35 0.46 8.57 0.42 3.54e-16 Testicular germ cell tumor; LIHC cis rs1707322 1.000 rs10890359 chr1:46336635 A/G cg03146154 chr1:46216737 IPP 0.47 7.5 0.38 5.65e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs798554 1.000 rs798536 chr7:2766383 G/A cg04166393 chr7:2884313 GNA12 0.44 6.07 0.31 3.41e-9 Height; LIHC cis rs4474465 0.688 rs10751296 chr11:78277277 C/T cg02023728 chr11:77925099 USP35 0.33 5.81 0.3 1.44e-8 Alzheimer's disease (survival time); LIHC cis rs3960554 0.800 rs112463197 chr7:75622912 C/T cg01364799 chr7:75623366 TMEM120A -0.46 -5.75 -0.3 1.99e-8 Eotaxin levels; LIHC cis rs10744422 0.748 rs2292138 chr12:123339712 A/G cg22842854 chr12:123319900 HIP1R -0.74 -9.83 -0.47 2.99e-20 Schizophrenia; LIHC cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg24549020 chr5:56110836 MAP3K1 0.49 6.33 0.32 7.79e-10 Initial pursuit acceleration; LIHC cis rs9381040 0.655 rs2268187 chr6:41042993 G/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.38 -6.16 -0.32 2.05e-9 Alzheimer's disease (late onset); LIHC cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs875971 0.895 rs4145009 chr7:65726615 T/C cg18876405 chr7:65276391 NA -0.34 -6.05 -0.31 3.84e-9 Aortic root size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18393722 chr15:85113863 UBE2QP1 0.37 6.09 0.31 3.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504073 0.584 rs11776843 chr8:49928449 C/T cg00325661 chr8:49890786 NA 0.39 9.55 0.46 2.5e-19 Blood metabolite ratios; LIHC cis rs8083850 0.635 rs10469024 chr18:50863609 A/C cg24270629 chr18:50823537 DCC 0.53 8.04 0.4 1.51e-14 Intelligence (multi-trait analysis); LIHC cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg11301795 chr4:187892539 NA -0.26 -7.0 -0.35 1.32e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs10792665 0.844 rs10898058 chr11:82657859 T/A cg24227371 chr11:82718527 RAB30 -0.31 -7.23 -0.36 3.15e-12 Obesity-related traits; LIHC cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.43 7.36 0.37 1.35e-12 Height; LIHC cis rs17102423 0.755 rs35769504 chr14:65576857 G/A cg11161011 chr14:65562177 MAX -0.59 -8.24 -0.41 3.65e-15 Obesity-related traits; LIHC cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg08888203 chr3:10149979 C3orf24 0.55 6.35 0.32 6.76e-10 Alzheimer's disease; LIHC cis rs10193935 1.000 rs4048 chr2:42424595 A/C cg27598129 chr2:42591480 NA -0.73 -11.1 -0.51 1.17e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs116095464 0.558 rs9312956 chr5:201812 T/C cg22496380 chr5:211416 CCDC127 -1.19 -10.56 -0.5 9.27e-23 Breast cancer; LIHC cis rs7020830 0.931 rs9775431 chr9:37130433 G/A cg14294708 chr9:37120828 ZCCHC7 1.07 22.69 0.78 3.42e-70 Schizophrenia; LIHC trans rs61931739 0.500 rs10844844 chr12:34380350 G/T cg26384229 chr12:38710491 ALG10B 0.74 8.7 0.43 1.46e-16 Morning vs. evening chronotype; LIHC cis rs908922 0.542 rs4845785 chr1:152510143 C/T cg23254163 chr1:152506842 NA 0.23 5.97 0.31 5.81e-9 Hair morphology; LIHC cis rs7523273 0.505 rs35438924 chr1:207881489 T/G cg22525895 chr1:207977042 MIR29B2 0.49 7.68 0.38 1.75e-13 Schizophrenia; LIHC cis rs2295359 0.892 rs4655687 chr1:67649946 C/T cg12940439 chr1:67600707 NA 0.35 6.17 0.32 1.95e-9 Psoriasis; LIHC cis rs7833790 0.632 rs6415653 chr8:82702536 A/G cg17211192 chr8:82754475 SNX16 -0.53 -9.32 -0.45 1.45e-18 Diastolic blood pressure; LIHC cis rs116095464 0.558 rs6878087 chr5:223117 C/T cg22496380 chr5:211416 CCDC127 0.94 9.52 0.46 3.27e-19 Breast cancer; LIHC cis rs477692 0.967 rs488143 chr10:131407369 A/C cg19680672 chr10:131412579 MGMT -0.44 -6.94 -0.35 1.94e-11 Response to temozolomide; LIHC cis rs72634258 0.554 rs10462018 chr1:7879627 C/T cg26816564 chr1:7831052 VAMP3 0.6 6.44 0.33 4.05e-10 Inflammatory bowel disease; LIHC cis rs55665837 0.922 rs12287212 chr11:14449861 C/A cg19336497 chr11:14380999 RRAS2 -0.45 -8.41 -0.41 1.11e-15 Vitamin D levels; LIHC trans rs66887589 0.777 rs2017058 chr4:120257739 T/C cg25214090 chr10:38739885 LOC399744 0.4 6.73 0.34 6.99e-11 Diastolic blood pressure; LIHC cis rs17685 0.712 rs1639620 chr7:75704090 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs523522 0.962 rs3213565 chr12:120992401 C/T cg27279351 chr12:120934652 DYNLL1 0.67 11.93 0.54 1.11e-27 High light scatter reticulocyte count; LIHC cis rs12135894 0.562 rs6688969 chr1:3743391 C/T cg26550851 chr1:3701203 LRRC47 0.4 6.99 0.35 1.48e-11 Mean corpuscular volume; LIHC cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg00149659 chr3:10157352 C3orf10 0.68 7.11 0.36 6.86e-12 Alzheimer's disease; LIHC cis rs45430 1.000 rs408825 chr21:42743496 A/G cg06102954 chr21:42741788 MX2 -0.36 -6.25 -0.32 1.25e-9 Melanoma; LIHC cis rs12477438 0.798 rs13412764 chr2:99583733 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.06 -14.67 -0.62 3.78e-38 Chronic sinus infection; LIHC cis rs1816752 0.666 rs7994022 chr13:25017230 A/G cg02811702 chr13:24901961 NA 0.25 6.41 0.33 4.83e-10 Obesity-related traits; LIHC trans rs955333 1.000 rs56306994 chr6:154946059 T/C cg01304710 chr4:3766151 NA 0.31 6.44 0.33 3.97e-10 Diabetic kidney disease; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg10081115 chr2:190686883 PMS1 0.59 7.19 0.36 4.22e-12 Lung function (FEV1); LIHC trans rs7849581 1 rs7849581 chr9:9924724 A/G cg01762264 chr16:3192406 ZNF213 -0.54 -6.16 -0.32 2.02e-9 Myopia (pathological); LIHC cis rs7772486 0.875 rs9322046 chr6:146393625 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.84 -0.3 1.19e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg09331704 chr11:110167585 RDX -0.54 -6.04 -0.31 4.08e-9 Systolic blood pressure; LIHC cis rs801193 1.000 rs13239306 chr7:66136017 T/G cg11764359 chr7:65958608 NA -0.6 -8.52 -0.42 5e-16 Aortic root size; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg14828511 chr1:107599125 PRMT6 -0.44 -6.25 -0.32 1.22e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg08132940 chr7:1081526 C7orf50 -0.74 -6.35 -0.32 6.81e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs941408 0.890 rs1640269 chr19:2793194 A/C cg19676328 chr12:49525230 TUBA1B -0.39 -6.31 -0.32 8.59e-10 Total cholesterol levels; LIHC cis rs986417 1.000 rs1956555 chr14:60968804 A/G cg27398547 chr14:60952738 C14orf39 0.85 9.85 0.47 2.61e-20 Gut microbiota (bacterial taxa); LIHC trans rs11098499 0.909 rs79026312 chr4:120440677 C/A cg25214090 chr10:38739885 LOC399744 0.62 9.98 0.47 9.69e-21 Corneal astigmatism; LIHC cis rs7116495 1.000 rs677279 chr11:71770469 G/A cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs9457247 0.602 rs13204839 chr6:167471119 G/A cg07741184 chr6:167504864 NA 0.35 8.11 0.4 9.26e-15 Crohn's disease; LIHC cis rs11608355 0.545 rs35590455 chr12:109893514 A/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg26531700 chr6:26746687 NA 0.37 6.14 0.32 2.25e-9 Intelligence (multi-trait analysis); LIHC cis rs7917772 0.503 rs61871067 chr10:104295382 C/T cg22532475 chr10:104410764 TRIM8 -0.37 -6.13 -0.31 2.43e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs769267 0.895 rs2965189 chr19:19519518 G/T cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.22 0.32 1.41e-9 Tonsillectomy; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04334947 chr13:30881232 KATNAL1 -0.55 -6.31 -0.32 8.78e-10 Systolic blood pressure; LIHC cis rs270601 0.739 rs3900945 chr5:131592870 T/C cg24060327 chr5:131705240 SLC22A5 -0.52 -6.9 -0.35 2.46e-11 Acylcarnitine levels; LIHC cis rs16958440 0.737 rs16958699 chr18:44654846 T/C cg17192377 chr18:44677553 HDHD2 0.6 6.74 0.34 6.88e-11 Sitting height ratio; LIHC cis rs873946 0.586 rs11146503 chr10:134565388 T/C cg26818010 chr10:134567672 INPP5A -0.76 -9.2 -0.45 3.53e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg22663859 chr13:21900854 NA 0.46 7.32 0.37 1.79e-12 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs765787 0.530 rs4544188 chr15:45535393 C/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC cis rs1707322 0.964 rs785499 chr1:46592420 G/A cg06784218 chr1:46089804 CCDC17 -0.4 -7.22 -0.36 3.38e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11583043 0.957 rs6667932 chr1:101503755 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.59 7.91 0.39 3.51e-14 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9810089 0.814 rs864437 chr3:136119909 C/G cg21827317 chr3:136751795 NA 0.43 5.78 0.3 1.71e-8 Gestational age at birth (child effect); LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.84 0.39 5.9e-14 Prudent dietary pattern; LIHC cis rs1552244 0.515 rs67342818 chr3:10166406 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs875971 0.660 rs13224319 chr7:66007363 A/G cg18876405 chr7:65276391 NA 0.44 7.78 0.39 8.74e-14 Aortic root size; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21930229 chr1:32758033 HDAC1 0.48 7.01 0.35 1.25e-11 Cognitive function; LIHC cis rs17253792 0.822 rs10483643 chr14:56089931 G/C cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC trans rs7618501 0.633 rs12496973 chr3:50002245 T/C cg21659725 chr3:3221576 CRBN 0.67 11.05 0.51 1.82e-24 Intelligence (multi-trait analysis); LIHC cis rs600806 0.714 rs12137189 chr1:110013215 A/G cg16275483 chr1:110013120 SYPL2 -0.49 -6.27 -0.32 1.1e-9 Intelligence (multi-trait analysis); LIHC cis rs10464366 0.571 rs4723825 chr7:39157627 G/C cg15212455 chr7:39170539 POU6F2 0.48 8.49 0.42 6.22e-16 IgG glycosylation; LIHC cis rs5769765 0.730 rs62233964 chr22:50317410 C/G cg26441486 chr22:50317300 CRELD2 0.38 6.5 0.33 2.85e-10 Schizophrenia; LIHC cis rs9325144 0.505 rs826893 chr12:39100536 A/G cg13010199 chr12:38710504 ALG10B -0.38 -5.94 -0.31 7.11e-9 Morning vs. evening chronotype; LIHC cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg05025164 chr4:1340916 KIAA1530 0.43 6.62 0.34 1.38e-10 Obesity-related traits; LIHC cis rs5769765 0.740 rs2103932 chr22:50272515 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.69 8.99 0.44 1.75e-17 Schizophrenia; LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.753 rs11982200 chr7:75714883 T/C cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17685 0.712 rs10275521 chr7:75770972 T/C cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4478037 0.732 rs12490111 chr3:33103007 G/A cg16652328 chr3:33138982 GLB1;TMPPE -0.58 -6.85 -0.35 3.43e-11 Major depressive disorder; LIHC cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.58 -0.34 1.76e-10 Gut microbiome composition (summer); LIHC cis rs9911578 1.000 rs368186 chr17:56736659 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs7528419 0.895 rs583104 chr1:109821307 G/T cg20569855 chr1:109824440 PSRC1 0.49 6.65 0.34 1.15e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.88 0.3 9.86e-9 Menopause (age at onset); LIHC cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg13271783 chr10:134563150 INPP5A -0.57 -7.18 -0.36 4.46e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs60871478 1.000 rs6460801 chr7:810506 T/C cg13844804 chr7:814759 HEATR2 0.43 5.81 0.3 1.44e-8 Cerebrospinal P-tau181p levels; LIHC cis rs1697139 0.935 rs1623654 chr5:66512819 A/T cg16691251 chr5:66510806 NA 0.51 7.26 0.37 2.68e-12 Breast cancer; LIHC cis rs4934494 0.768 rs12771413 chr10:91392767 C/T cg19698084 chr10:91461284 KIF20B 0.47 6.59 0.34 1.7e-10 Red blood cell count; LIHC cis rs7312933 0.510 rs10880223 chr12:42413443 G/A cg01256987 chr12:42539512 GXYLT1 -0.63 -11.67 -0.53 1.05e-26 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs801193 0.805 rs12532355 chr7:66070584 C/G cg14393609 chr7:65229607 NA -0.35 -5.77 -0.3 1.75e-8 Aortic root size; LIHC cis rs6674176 0.660 rs2108202 chr1:44395786 A/G cg12908607 chr1:44402522 ARTN 0.49 8.21 0.41 4.71e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6088580 0.634 rs4911418 chr20:32994257 G/A cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs2066819 1.000 rs2643626 chr12:56726518 C/T cg26734620 chr12:56694298 CS -1.0 -10.11 -0.48 3.46e-21 Psoriasis vulgaris; LIHC cis rs7188697 0.922 rs37039 chr16:58578091 C/T cg02549819 chr16:58548995 SETD6 -0.46 -7.27 -0.37 2.47e-12 QT interval; LIHC cis rs9325144 0.600 rs7965877 chr12:38743697 G/T cg26384229 chr12:38710491 ALG10B 0.59 8.21 0.41 4.57e-15 Morning vs. evening chronotype; LIHC cis rs1552244 0.882 rs34706481 chr3:10004123 G/A cg08888203 chr3:10149979 C3orf24 0.47 5.79 0.3 1.59e-8 Alzheimer's disease; LIHC trans rs11148252 0.811 rs9536030 chr13:52938291 G/A cg18335740 chr13:41363409 SLC25A15 -0.38 -6.61 -0.34 1.49e-10 Lewy body disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01855760 chr4:68567075 LOC550112;UBA6 0.59 8.1 0.4 1.01e-14 Pancreatic cancer; LIHC cis rs10751667 0.961 rs6597971 chr11:928598 T/A cg10932868 chr11:921992 NA 0.35 6.56 0.33 1.96e-10 Alzheimer's disease (late onset); LIHC cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg25072359 chr17:41440525 NA 0.38 6.07 0.31 3.31e-9 Menopause (age at onset); LIHC cis rs2637266 1.000 rs10824425 chr10:78340310 C/G cg18941641 chr10:78392320 NA 0.28 5.97 0.31 5.96e-9 Pulmonary function; LIHC cis rs9393777 0.513 rs7754159 chr6:26620312 G/A cg12826209 chr6:26865740 GUSBL1 0.55 5.71 0.3 2.44e-8 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg00091569 chr3:40428383 ENTPD3 0.41 6.98 0.35 1.5e-11 Renal cell carcinoma; LIHC cis rs703842 1.000 rs10783847 chr12:58196447 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.82 13.59 0.59 5.99e-34 Multiple sclerosis; LIHC cis rs55665837 0.540 rs7938266 chr11:14709324 A/G cg00085434 chr11:14927489 NA 0.41 5.82 0.3 1.35e-8 Vitamin D levels; LIHC cis rs16858210 0.874 rs10937153 chr3:183562925 A/G cg25686905 chr3:183603175 PARL 0.48 9.22 0.45 3.08e-18 Menopause (age at onset); LIHC cis rs7216064 0.953 rs8073510 chr17:65839210 A/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.34 -0.45 1.31e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2412488 0.861 rs11722866 chr4:54310188 A/G cg22241045 chr4:54363911 LNX1 -0.41 -6.66 -0.34 1.07e-10 DNA methylation (variation); LIHC cis rs10791097 0.694 rs4456262 chr11:130755813 C/T cg14779329 chr11:130786720 SNX19 -0.46 -6.67 -0.34 1.04e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs61160187 0.503 rs377321 chr5:59851740 G/C cg02684056 chr5:59996105 DEPDC1B 0.4 6.0 0.31 5.05e-9 Educational attainment (years of education);Educational attainment (college completion); LIHC cis rs2380220 0.938 rs6923253 chr6:95970141 C/G cg15832292 chr6:96025679 MANEA 0.63 7.02 0.36 1.16e-11 Behavioural disinhibition (generation interaction); LIHC cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg23205692 chr1:25664452 TMEM50A 0.43 6.92 0.35 2.29e-11 Erythrocyte sedimentation rate; LIHC cis rs7572733 0.534 rs1983359 chr2:198805098 C/T cg03934865 chr2:198174659 NA 0.46 6.79 0.34 5.08e-11 Dermatomyositis; LIHC cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg00280220 chr17:61926910 NA 0.43 6.82 0.35 4.18e-11 Prudent dietary pattern; LIHC cis rs10464366 0.517 rs13231075 chr7:39174806 G/T cg18850127 chr7:39170497 POU6F2 0.45 8.07 0.4 1.2e-14 IgG glycosylation; LIHC cis rs4474465 1.000 rs10793315 chr11:78190716 C/G cg27205649 chr11:78285834 NARS2 -0.39 -5.8 -0.3 1.49e-8 Alzheimer's disease (survival time); LIHC cis rs7552404 1.000 rs437298 chr1:76113770 T/C cg03433033 chr1:76189801 ACADM -0.68 -9.51 -0.46 3.48e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs8062405 0.823 rs7202948 chr16:28558289 T/A cg00204512 chr16:28754710 NA 0.35 7.01 0.35 1.31e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs60871478 0.578 rs62432900 chr7:826794 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.52 6.02 0.31 4.48e-9 Cerebrospinal P-tau181p levels; LIHC cis rs2404602 0.647 rs11631394 chr15:76973209 G/T cg03037974 chr15:76606532 NA -0.59 -10.09 -0.48 3.95e-21 Blood metabolite levels; LIHC cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg20887711 chr4:1340912 KIAA1530 0.45 6.01 0.31 4.77e-9 Obesity-related traits; LIHC cis rs9640161 0.830 rs3735165 chr7:150068371 T/C cg21361702 chr7:150065534 REPIN1 0.52 7.3 0.37 2e-12 Blood protein levels;Circulating chemerin levels; LIHC cis rs7412746 0.611 rs7556661 chr1:150892009 C/T cg18016565 chr1:150552671 MCL1 0.52 9.95 0.47 1.21e-20 Melanoma; LIHC cis rs634534 0.562 rs642293 chr11:65730217 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 9.11 0.44 7.24e-18 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg06634786 chr22:41940651 POLR3H -0.75 -8.2 -0.41 5.01e-15 Vitiligo; LIHC cis rs7208859 0.573 rs216442 chr17:28931197 T/G cg13385521 chr17:29058706 SUZ12P 0.67 6.57 0.33 1.88e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9814567 1.000 rs2373865 chr3:134291556 C/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.86 0.3 1.08e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2180341 1.000 rs7756336 chr6:127650299 T/C cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs57502260 1.000 rs56312530 chr11:68219415 G/A cg20283391 chr11:68216788 NA -0.46 -5.77 -0.3 1.74e-8 Total body bone mineral density (age 45-60); LIHC cis rs12744310 1.000 rs56077539 chr1:41773942 T/C cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC trans rs4927850 1.000 rs7625570 chr3:195747398 A/G cg16724585 chr3:197361211 NA -0.47 -6.63 -0.34 1.29e-10 Pancreatic cancer; LIHC cis rs1555322 0.530 rs2425049 chr20:33874720 C/T cg17927777 chr20:33865990 NA 0.52 6.23 0.32 1.41e-9 Attention deficit hyperactivity disorder; LIHC cis rs7818688 0.697 rs11781757 chr8:95987891 A/T cg16049864 chr8:95962084 TP53INP1 0.59 6.4 0.33 5.08e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg12311636 chr6:118886798 C6orf204 -0.53 -6.22 -0.32 1.44e-9 Diastolic blood pressure; LIHC cis rs3820068 0.705 rs11577225 chr1:15864242 T/C cg17385448 chr1:15911702 AGMAT 0.41 6.91 0.35 2.36e-11 Systolic blood pressure; LIHC cis rs4474465 0.831 rs12287010 chr11:78161452 A/T cg27205649 chr11:78285834 NARS2 0.39 5.93 0.31 7.44e-9 Alzheimer's disease (survival time); LIHC cis rs7927771 0.524 rs4752796 chr11:47841862 A/G cg20307385 chr11:47447363 PSMC3 -0.66 -9.97 -0.47 1.01e-20 Subjective well-being; LIHC cis rs74417235 0.684 rs13179358 chr5:154059746 C/A cg19735590 chr5:154026979 NA 0.47 5.82 0.3 1.39e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs12908161 1.000 rs12899981 chr15:85302373 G/A cg17507749 chr15:85114479 UBE2QP1 0.62 7.04 0.36 1.09e-11 Schizophrenia; LIHC cis rs57590327 0.528 rs13086292 chr3:81705368 G/A cg07356753 chr3:81810745 GBE1 -0.54 -8.13 -0.4 8.06e-15 Extraversion; LIHC cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg24549020 chr5:56110836 MAP3K1 0.5 6.43 0.33 4.23e-10 Initial pursuit acceleration; LIHC cis rs1355223 0.902 rs61881050 chr11:34719749 G/A cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.36 -0.33 6.58e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6867032 1.000 rs2129472 chr5:2016247 G/A cg26168224 chr5:2018326 NA 0.31 7.57 0.38 3.48e-13 Gut microbiome composition (winter); LIHC cis rs6750047 0.719 rs100489 chr2:38266478 T/C cg07380506 chr2:38303506 CYP1B1 -0.52 -6.08 -0.31 3.27e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs4665809 1.000 rs10182857 chr2:26344411 C/T cg27170947 chr2:26402098 FAM59B -0.65 -8.23 -0.41 3.86e-15 Gut microbiome composition (summer); LIHC cis rs10489202 1.000 rs718885 chr1:167954659 A/G cg24449463 chr1:168025552 DCAF6 -0.53 -6.72 -0.34 7.5e-11 Schizophrenia; LIHC cis rs12586317 0.534 rs28384418 chr14:35452126 C/A cg05294307 chr14:35346193 BAZ1A -0.48 -7.69 -0.38 1.55e-13 Psoriasis; LIHC cis rs9814567 1.000 rs9883753 chr3:134247231 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs17345786 0.798 rs9817043 chr3:101281852 A/G cg11279151 chr3:101281821 RG9MTD1 -0.54 -8.8 -0.43 6.99e-17 Colonoscopy-negative controls vs population controls; LIHC cis rs9341808 0.529 rs2322765 chr6:81064596 A/G cg08355045 chr6:80787529 NA 0.34 6.9 0.35 2.54e-11 Sitting height ratio; LIHC cis rs6456156 0.586 rs12213801 chr6:167474084 T/A cg12798992 chr6:167411361 FGFR1OP 0.51 8.3 0.41 2.5e-15 Primary biliary cholangitis; LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs754466 0.606 rs11002308 chr10:79594796 A/T cg17075019 chr10:79541650 NA -0.78 -12.09 -0.55 3.05e-28 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03390569 chr2:54013802 LOC100302652;ASB3;ERLEC1 -0.41 -6.41 -0.33 4.9e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs10751667 0.666 rs7395488 chr11:954111 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.09 0.48 4.1e-21 Alzheimer's disease (late onset); LIHC cis rs9902453 1.000 rs57411618 chr17:28273052 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 12.2 0.55 1.13e-28 Coffee consumption (cups per day); LIHC cis rs921968 0.643 rs1055816 chr2:219501328 G/A cg02985541 chr2:219472218 PLCD4 0.41 7.5 0.38 5.49e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs2236918 0.710 rs1635510 chr1:242027500 G/T cg17736920 chr1:242011382 EXO1 0.42 6.24 0.32 1.3e-9 Menopause (age at onset); LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.49 7.15 0.36 5.4e-12 Lymphocyte counts; LIHC cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg05016508 chr11:63871570 FLRT1;MACROD1 0.47 5.72 0.3 2.32e-8 Mean platelet volume; LIHC cis rs2795502 1.000 rs2795497 chr10:43339475 C/A cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs727505 0.954 rs1525613 chr7:124658636 A/G cg23710748 chr7:124431027 NA -0.33 -5.88 -0.3 9.64e-9 Lewy body disease; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg26541587 chr10:43950885 ZNF487 -0.42 -6.26 -0.32 1.17e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs61990749 0.597 rs2267758 chr14:78147429 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.18 -0.48 1.9e-21 Fibroblast growth factor basic levels; LIHC cis rs1997103 0.798 rs12154964 chr7:55414041 G/A cg17469321 chr7:55412551 NA 0.49 7.15 0.36 5.29e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7904368 0.806 rs1130684 chr10:16859335 C/G cg23933602 chr10:16859644 RSU1 0.55 5.73 0.3 2.26e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs9733 0.744 rs3754211 chr1:150951857 G/A cg18016565 chr1:150552671 MCL1 0.48 9.03 0.44 1.3e-17 Tonsillectomy; LIHC cis rs6424115 1.000 rs12031592 chr1:24127864 A/C cg10978503 chr1:24200527 CNR2 0.33 7.77 0.39 9.06e-14 Immature fraction of reticulocytes; LIHC cis rs2742417 0.603 rs13059502 chr3:45781380 A/G cg04837898 chr3:45731254 SACM1L -0.51 -8.61 -0.42 2.64e-16 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs8062405 0.690 rs762634 chr16:28603335 T/C cg07451762 chr16:28383216 NA 0.41 7.05 0.36 9.65e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.16 -0.32 2.05e-9 Colorectal cancer; LIHC cis rs2274273 0.745 rs56262555 chr14:55561962 C/T cg01864836 chr14:55583639 NA -0.38 -6.57 -0.33 1.91e-10 Protein biomarker; LIHC cis rs9902453 0.845 rs7222842 chr17:28246943 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.93 0.54 1.17e-27 Coffee consumption (cups per day); LIHC cis rs11628318 0.614 rs7145737 chr14:103121784 T/A cg12046867 chr14:103022105 NA 0.48 6.93 0.35 2.14e-11 Platelet count; LIHC cis rs11122272 0.735 rs2790890 chr1:231514567 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.78e-23 Hemoglobin concentration; LIHC cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.6 0.38 2.85e-13 Bipolar disorder; LIHC cis rs6547741 1.000 rs7604798 chr2:27824940 T/C cg27432699 chr2:27873401 GPN1 0.72 11.74 0.54 5.55e-27 Oral cavity cancer; LIHC cis rs2832191 0.935 rs11910475 chr21:30519702 T/C cg08807101 chr21:30365312 RNF160 -0.52 -8.28 -0.41 2.89e-15 Dental caries; LIHC cis rs7582720 0.943 rs115827549 chr2:203725678 A/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.76 6.15 0.32 2.15e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs11190604 0.767 rs10883483 chr10:102174244 T/C cg07080220 chr10:102295463 HIF1AN 0.45 6.15 0.32 2.12e-9 Palmitoleic acid (16:1n-7) levels; LIHC cis rs12478296 1.000 rs4973685 chr2:243019089 A/C cg06360820 chr2:242988706 NA -0.95 -12.54 -0.56 5.9e-30 Obesity-related traits; LIHC cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg02290350 chr8:58132656 NA 0.43 8.72 0.43 1.24e-16 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.590 rs6944104 chr7:139051120 T/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg14780466 chr2:20870812 GDF7 -0.42 -8.71 -0.43 1.29e-16 Abdominal aortic aneurysm; LIHC cis rs6545883 0.894 rs12615783 chr2:61440947 T/C cg14146966 chr2:61757674 XPO1 -0.43 -7.13 -0.36 5.92e-12 Tuberculosis; LIHC cis rs9457247 0.663 rs9459839 chr6:167431829 T/C cg23791538 chr6:167370224 RNASET2 -0.53 -8.79 -0.43 7.28e-17 Crohn's disease; LIHC cis rs7552404 0.855 rs385897 chr1:76106962 T/C cg03433033 chr1:76189801 ACADM -0.69 -9.95 -0.47 1.23e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7617480 0.648 rs14018 chr3:48784270 G/A cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.28 0.32 1.03e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs1878931 0.668 rs2074366 chr16:3439676 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 22.02 0.77 1.55e-67 Body mass index (adult); LIHC cis rs992157 0.730 rs2382828 chr2:219184492 A/G cg00012203 chr2:219082015 ARPC2 0.76 10.74 0.5 2.16e-23 Colorectal cancer; LIHC cis rs7539409 0.651 rs6576953 chr1:84316946 A/G cg10977910 chr1:84465055 TTLL7 0.72 7.17 0.36 4.68e-12 Alzheimer's disease; LIHC cis rs11673344 0.542 rs826331 chr19:37498262 G/A cg27390819 chr19:37464633 NA -0.46 -6.12 -0.31 2.61e-9 Obesity-related traits; LIHC cis rs6964587 1.000 rs10488512 chr7:91753579 C/T cg17063962 chr7:91808500 NA 1.01 19.18 0.72 3.65e-56 Breast cancer; LIHC cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg10802521 chr3:52805072 NEK4 -0.43 -7.22 -0.36 3.34e-12 Bipolar disorder; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg20064231 chr18:74608296 ZNF236 0.47 6.17 0.32 1.9e-9 Hepatitis; LIHC cis rs12950390 0.893 rs11079789 chr17:45849715 A/G cg03474202 chr17:45855739 NA -0.35 -6.05 -0.31 3.73e-9 IgG glycosylation; LIHC cis rs61861422 0.516 rs12412216 chr10:134393338 C/T cg20090690 chr10:134436459 INPP5A 0.56 7.96 0.4 2.57e-14 Primary sclerosing cholangitis; LIHC cis rs986417 1.000 rs6573312 chr14:60952536 G/T cg27398547 chr14:60952738 C14orf39 0.83 9.68 0.46 9.59e-20 Gut microbiota (bacterial taxa); LIHC trans rs66887589 0.934 rs7681980 chr4:120533223 G/A cg25214090 chr10:38739885 LOC399744 -0.41 -6.82 -0.35 4.25e-11 Diastolic blood pressure; LIHC cis rs2257205 0.667 rs9916423 chr17:56773834 T/C cg12560992 chr17:57184187 TRIM37 0.72 7.97 0.4 2.33e-14 Pancreatic cancer; LIHC trans rs11098499 0.954 rs11940028 chr4:120411907 T/C cg25214090 chr10:38739885 LOC399744 0.57 9.44 0.45 6.19e-19 Corneal astigmatism; LIHC cis rs9309473 0.948 rs13392691 chr2:73748980 G/A cg20560298 chr2:73613845 ALMS1 -0.56 -6.65 -0.34 1.19e-10 Metabolite levels; LIHC cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg00166722 chr3:10149974 C3orf24 -0.45 -5.73 -0.3 2.16e-8 Alzheimer's disease; LIHC trans rs17685 0.712 rs7778735 chr7:75770237 T/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.25 0.72 1.81e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg15691649 chr6:25882328 NA -0.53 -7.77 -0.39 9.49e-14 Blood metabolite levels; LIHC cis rs9790314 0.521 rs1450522 chr3:161077630 A/G cg17135325 chr3:160939158 NMD3 0.54 7.82 0.39 6.61e-14 Morning vs. evening chronotype; LIHC cis rs2625529 0.823 rs11072332 chr15:72108307 G/T cg16672083 chr15:72433130 SENP8 -0.32 -5.93 -0.31 7.3e-9 Red blood cell count; LIHC cis rs10751667 0.666 rs6597958 chr11:978087 C/T cg06064525 chr11:970664 AP2A2 -0.56 -14.98 -0.63 2.3e-39 Alzheimer's disease (late onset); LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg15555402 chr12:19593456 AEBP2 -0.45 -6.35 -0.32 6.86e-10 Thyroid stimulating hormone; LIHC cis rs6933660 0.760 rs6904364 chr6:151754273 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.49 7.32 0.37 1.76e-12 Menarche (age at onset); LIHC cis rs739401 0.595 rs2237903 chr11:2967901 C/T cg20651018 chr11:3035856 CARS -0.37 -6.33 -0.32 7.6e-10 Longevity; LIHC cis rs3785574 0.962 rs2727280 chr17:61918082 A/G cg11494091 chr17:61959527 GH2 0.36 5.93 0.31 7.39e-9 Height; LIHC cis rs6831352 0.589 rs1133483 chr4:100023923 G/C cg13256891 chr4:100009986 ADH5 0.46 6.52 0.33 2.59e-10 Alcohol dependence; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg26338869 chr17:61819248 STRADA 0.58 8.53 0.42 4.73e-16 Prudent dietary pattern; LIHC cis rs9952991 0.941 rs2542149 chr18:12779018 G/A cg23598886 chr18:12777645 NA 0.48 6.51 0.33 2.69e-10 Inflammatory skin disease; LIHC cis rs870825 0.860 rs72703525 chr4:185605154 T/C cg04058563 chr4:185651563 MLF1IP 0.76 6.49 0.33 3.05e-10 Blood protein levels; LIHC cis rs8180040 0.966 rs7628631 chr3:47560863 C/T cg16586182 chr3:47516702 SCAP 0.41 7.21 0.36 3.71e-12 Colorectal cancer; LIHC cis rs1046896 0.512 rs3785513 chr17:80886748 G/A cg02398342 chr17:80708632 TBCD;FN3K 0.42 6.64 0.34 1.26e-10 Glycated hemoglobin levels; LIHC cis rs748404 0.660 rs2439846 chr15:43740970 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.14 0.36 5.5e-12 Lung cancer; LIHC cis rs763121 0.853 rs2072796 chr22:39064230 A/G cg06022373 chr22:39101656 GTPBP1 0.64 11.11 0.51 1.08e-24 Menopause (age at onset); LIHC cis rs6748734 0.817 rs4465762 chr2:241798862 G/A cg20140201 chr2:241835670 C2orf54 -0.5 -7.74 -0.39 1.14e-13 Urinary metabolites; LIHC trans rs11225569 0.539 rs3910097 chr11:103244313 A/T cg15013544 chr3:76558527 NA 0.35 6.34 0.32 7.22e-10 Diisocyanate-induced asthma; LIHC cis rs7617773 0.779 rs3731487 chr3:48229624 C/T cg11946769 chr3:48343235 NME6 0.9 11.12 0.52 9.62e-25 Coronary artery disease; LIHC cis rs11690935 0.632 rs6737308 chr2:172872042 G/A cg13550731 chr2:172543902 DYNC1I2 0.44 6.68 0.34 9.91e-11 Schizophrenia; LIHC cis rs1008375 1.000 rs28693609 chr4:17645233 C/T cg04450456 chr4:17643702 FAM184B 0.34 5.82 0.3 1.36e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs8073060 0.572 rs1634683 chr17:33941560 G/C cg19694781 chr19:47549865 TMEM160 -1.21 -12.46 -0.56 1.18e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs908922 0.676 rs528427 chr1:152511507 G/C cg20991723 chr1:152506922 NA 0.54 9.45 0.46 5.37e-19 Hair morphology; LIHC cis rs79839061 0.610 rs3775122 chr4:893287 A/G cg07828340 chr4:882639 GAK -0.81 -6.84 -0.35 3.67e-11 Intelligence (multi-trait analysis); LIHC cis rs11958404 0.860 rs6868839 chr5:157442196 T/G cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs7772486 0.806 rs4075695 chr6:146250959 A/G cg05347473 chr6:146136440 FBXO30 -0.36 -6.08 -0.31 3.23e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4853012 0.887 rs77148265 chr2:74339519 C/T cg05890377 chr2:74357713 NA 0.64 12.53 0.56 6.45e-30 Gestational age at birth (maternal effect); LIHC cis rs1568889 1.000 rs12797689 chr11:28076042 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.48 6.5 0.33 2.91e-10 Bipolar disorder; LIHC cis rs13223928 0.621 rs4722438 chr7:3155813 A/G cg19214707 chr7:3157722 NA 0.41 7.73 0.39 1.25e-13 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; LIHC cis rs7395581 0.918 rs12575456 chr11:47326073 G/A cg25783544 chr11:47291846 MADD 0.41 5.94 0.31 6.98e-9 HDL cholesterol; LIHC cis rs11588062 0.601 rs4660344 chr1:46805222 A/G cg23431851 chr1:46668822 C1orf190;POMGNT1 0.46 7.39 0.37 1.1e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2153535 0.580 rs7742794 chr6:8459723 C/A cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs7107174 0.901 rs4944199 chr11:78122779 A/G cg27205649 chr11:78285834 NARS2 -0.37 -5.72 -0.3 2.3e-8 Testicular germ cell tumor; LIHC cis rs4555082 0.834 rs2816653 chr14:105713973 A/G cg13114125 chr14:105738426 BRF1 -0.68 -8.93 -0.43 2.74e-17 Mean platelet volume;Platelet distribution width; LIHC cis rs477895 0.838 rs11605738 chr11:64013406 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 9.26 0.45 2.26e-18 Mean platelet volume; LIHC cis rs7264396 0.790 rs11697903 chr20:34272224 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.68 -11.61 -0.53 1.76e-26 Total cholesterol levels; LIHC cis rs7131987 0.903 rs10843367 chr12:29408380 G/A cg16970926 chr12:29381810 FAR2 0.3 6.24 0.32 1.27e-9 QT interval; LIHC trans rs2562456 0.526 rs950504 chr19:21783995 A/C cg11579907 chr6:151412213 MTHFD1L -0.4 -6.15 -0.32 2.11e-9 Pain; LIHC cis rs1403694 0.515 rs1624569 chr3:186450069 A/G cg12454167 chr3:186435060 KNG1 0.3 7.21 0.36 3.54e-12 Blood protein levels; LIHC cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg15691649 chr6:25882328 NA -0.52 -7.65 -0.38 2.07e-13 Blood metabolite levels; LIHC cis rs7772486 0.902 rs2777480 chr6:146309983 T/A cg23711669 chr6:146136114 FBXO30 0.56 9.72 0.47 6.98e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg24846343 chr22:24311635 DDTL -0.58 -10.21 -0.48 1.53e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4930103 0.935 rs4930101 chr11:2021859 G/T cg06197492 chr11:2016605 H19 0.39 6.37 0.33 6.28e-10 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs9660992 0.674 rs1151785 chr1:205232299 C/T cg21545522 chr1:205238299 TMCC2 0.43 8.13 0.4 8.01e-15 Mean corpuscular volume;Mean platelet volume; LIHC cis rs2153535 0.580 rs9406159 chr6:8464859 C/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs9393692 0.905 rs4412192 chr6:26290377 A/G cg13736514 chr6:26305472 NA 0.37 6.29 0.32 9.97e-10 Educational attainment; LIHC trans rs208515 0.525 rs1484577 chr6:66688397 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.76 8.78 0.43 8.23e-17 Exhaled nitric oxide levels; LIHC cis rs6840360 0.615 rs2406973 chr4:152608339 G/T cg22705602 chr4:152727874 NA 0.33 7.22 0.36 3.4e-12 Intelligence (multi-trait analysis); LIHC cis rs13064411 0.696 rs9869318 chr3:113146271 T/C cg18753928 chr3:113234510 CCDC52 -0.42 -5.74 -0.3 2.05e-8 Response to simvastatin treatment (PCSK9 protein level change); LIHC trans rs12780046 0.611 rs10883275 chr10:100881693 G/T cg05980083 chr9:112191166 PTPN3 -0.47 -6.08 -0.31 3.23e-9 Non-glioblastoma glioma; LIHC cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg20090690 chr10:134436459 INPP5A -0.43 -5.83 -0.3 1.27e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg08219700 chr8:58056026 NA 0.52 7.12 0.36 6.34e-12 Developmental language disorder (linguistic errors); LIHC cis rs9902453 0.765 rs3102560 chr17:28029938 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 13.6 0.59 5.86e-34 Coffee consumption (cups per day); LIHC cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg03874509 chr1:107600012 PRMT6 -0.76 -11.93 -0.54 1.14e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17685 0.753 rs10262501 chr7:75668172 G/A cg04592579 chr7:75616294 TMEM120A -0.4 -6.85 -0.35 3.39e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs12477438 0.765 rs2309454 chr2:99595418 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.45 -0.49 2.26e-22 Chronic sinus infection; LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.34 0.37 1.58e-12 Renal cell carcinoma; LIHC cis rs1816752 0.905 rs7571 chr13:25000617 C/G cg22771759 chr13:24902376 NA 0.33 6.79 0.34 5.09e-11 Obesity-related traits; LIHC cis rs2228479 0.850 rs76075456 chr16:89834270 T/C cg00800038 chr16:89945340 TCF25 -0.61 -8.97 -0.44 1.96e-17 Skin colour saturation; LIHC cis rs9534288 0.833 rs56813530 chr13:46622039 A/C cg15192986 chr13:46630673 CPB2 -0.57 -8.61 -0.42 2.76e-16 Blood protein levels; LIHC trans rs916888 0.773 rs199535 chr17:44822662 A/G cg07870213 chr5:140052090 DND1 1.03 10.38 0.49 4.11e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs921968 0.643 rs711186 chr2:219346102 A/G cg02985541 chr2:219472218 PLCD4 -0.43 -8.12 -0.4 8.78e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs1371867 0.875 rs1788168 chr8:101324960 G/T cg06002616 chr8:101225028 SPAG1 -0.34 -5.71 -0.3 2.44e-8 Atrioventricular conduction; LIHC cis rs600806 0.888 rs3768497 chr1:109866230 T/C cg16275483 chr1:110013120 SYPL2 -0.49 -6.11 -0.31 2.76e-9 Intelligence (multi-trait analysis); LIHC cis rs6442522 0.526 rs13074638 chr3:15518889 T/C cg16303742 chr3:15540471 COLQ 0.39 6.33 0.32 7.82e-10 Uric acid levels; LIHC cis rs7619427 0.507 rs6806526 chr3:44015285 T/C cg24966902 chr3:44043705 NA 0.44 6.83 0.35 3.83e-11 Schizophrenia; LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.86 -17.46 -0.69 3.01e-49 Prudent dietary pattern; LIHC cis rs6754311 0.773 rs632632 chr2:136638216 A/G cg07305463 chr2:136567211 LCT -0.4 -7.52 -0.38 4.99e-13 Mosquito bite size; LIHC cis rs747782 0.646 rs58119589 chr11:47571956 G/A cg20307385 chr11:47447363 PSMC3 -0.53 -6.14 -0.31 2.34e-9 Intraocular pressure; LIHC cis rs2404602 0.647 rs35940181 chr15:77180019 G/A cg23625390 chr15:77176239 SCAPER -0.57 -9.68 -0.46 9.91e-20 Blood metabolite levels; LIHC cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg09904177 chr6:26538194 HMGN4 -0.58 -12.02 -0.54 5.4e-28 Intelligence (multi-trait analysis); LIHC cis rs13427251 0.868 rs1901284 chr2:100146040 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.59 7.39 0.37 1.16e-12 Chronic sinus infection; LIHC cis rs801193 1.000 rs1553610 chr7:66197233 T/C cg11764359 chr7:65958608 NA 0.71 10.55 0.5 1.04e-22 Aortic root size; LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg02782426 chr3:40428986 ENTPD3 -0.35 -6.46 -0.33 3.52e-10 Renal cell carcinoma; LIHC cis rs11764590 0.715 rs56289396 chr7:2091415 G/A cg23422044 chr7:1970798 MAD1L1 -0.51 -5.81 -0.3 1.41e-8 Neuroticism; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg10795676 chr6:26370623 BTN3A2 0.42 6.17 0.32 1.97e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs875971 0.545 rs67775320 chr7:65658779 T/C cg11764359 chr7:65958608 NA 0.5 6.98 0.35 1.55e-11 Aortic root size; LIHC cis rs4474465 0.562 rs10793318 chr11:78215898 A/C cg27205649 chr11:78285834 NARS2 0.38 5.81 0.3 1.46e-8 Alzheimer's disease (survival time); LIHC cis rs9902453 0.967 rs61240589 chr17:28449035 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 8.99 0.44 1.77e-17 Coffee consumption (cups per day); LIHC cis rs780094 0.606 rs6729709 chr2:27583156 G/A cg22903471 chr2:27725779 GCKR -0.47 -7.94 -0.39 3.01e-14 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs10883723 0.810 rs10786669 chr10:104256094 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 13.13 0.58 3.68e-32 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg04267008 chr7:1944627 MAD1L1 -0.63 -10.03 -0.48 6.24e-21 Bipolar disorder and schizophrenia; LIHC cis rs9916302 0.851 rs6503502 chr17:37501855 A/G cg07936489 chr17:37558343 FBXL20 0.83 13.53 0.59 1.02e-33 Glomerular filtration rate (creatinine); LIHC cis rs2439831 0.850 rs7179388 chr15:44123945 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.37 0.41 1.53e-15 Lung cancer in ever smokers; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17015704 chr6:119400380 FAM184A 0.46 6.52 0.33 2.53e-10 Lung function (FEV1/FVC); LIHC cis rs1035144 0.510 rs12432357 chr14:81299468 A/G cg06600135 chr14:81408086 NA -0.46 -7.85 -0.39 5.48e-14 Male sexual orientation; LIHC cis rs3806843 1.000 rs7701755 chr5:140182101 G/T cg26395211 chr5:140044315 WDR55 -0.41 -6.13 -0.31 2.41e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs225245 0.610 rs321607 chr17:33880584 A/G cg05299278 chr17:33885742 SLFN14 0.23 6.06 0.31 3.62e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs1707322 0.721 rs4330955 chr1:46217485 G/C cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs668210 0.947 rs559161 chr11:65761637 A/G cg17712092 chr4:129076599 LARP1B 0.59 7.45 0.37 7.88e-13 Cerebrospinal fluid biomarker levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00080333 chr4:184492770 NA 0.38 6.91 0.35 2.44e-11 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02004021 chr12:95868393 METAP2 0.43 6.09 0.31 2.98e-9 Pancreatic cancer; LIHC cis rs709400 1.000 rs55885592 chr14:104126024 C/T cg26031613 chr14:104095156 KLC1 1.06 14.25 0.61 1.67e-36 Body mass index; LIHC cis rs9640161 0.789 rs10952250 chr7:150025966 T/C cg17279839 chr7:150038598 RARRES2 0.51 10.75 0.5 1.98e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs2573652 0.722 rs12595247 chr15:100541689 C/T cg09918751 chr15:100517450 ADAMTS17 -0.69 -12.46 -0.56 1.27e-29 Height; LIHC cis rs11190604 0.945 rs11190553 chr10:102207959 T/C cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs12701220 0.655 rs10215292 chr7:1135263 A/G cg18765753 chr7:1198926 ZFAND2A -0.4 -5.73 -0.3 2.21e-8 Bronchopulmonary dysplasia; LIHC cis rs7662987 0.517 rs2851260 chr4:100033574 C/T cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs4561483 0.799 rs33635 chr16:11991944 C/T cg08843971 chr16:11963173 GSPT1 -0.34 -6.89 -0.35 2.74e-11 Testicular germ cell tumor; LIHC cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg07308232 chr7:1071921 C7orf50 -0.48 -7.8 -0.39 7.71e-14 Longevity;Endometriosis; LIHC cis rs3749237 0.555 rs7637665 chr3:49552295 T/C cg07636037 chr3:49044803 WDR6 0.53 8.09 0.4 1.07e-14 Resting heart rate; LIHC cis rs7131987 0.903 rs2194518 chr12:29419460 C/T cg00204748 chr12:29376779 FAR2 0.38 6.84 0.35 3.73e-11 QT interval; LIHC cis rs6570726 0.935 rs377130 chr6:145836632 C/T cg23711669 chr6:146136114 FBXO30 0.55 9.89 0.47 1.95e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg06238570 chr21:40685208 BRWD1 -0.38 -6.1 -0.31 2.86e-9 Menarche (age at onset); LIHC cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg11764359 chr7:65958608 NA -0.55 -5.72 -0.3 2.29e-8 Diabetic kidney disease; LIHC cis rs9918079 0.560 rs6449153 chr4:15631216 C/T cg21123203 chr4:15471301 CC2D2A -0.41 -5.92 -0.3 7.89e-9 Obesity-related traits; LIHC cis rs17826219 0.636 rs2449770 chr17:29101064 G/T cg13385521 chr17:29058706 SUZ12P 0.84 8.27 0.41 3.06e-15 Body mass index; LIHC cis rs4407350 0.806 rs5765706 chr22:44909045 A/G cg04154583 chr22:44889756 LDOC1L 0.3 5.84 0.3 1.23e-8 Intelligence (multi-trait analysis); LIHC cis rs11190604 1.000 rs3793772 chr10:102222825 A/G cg07080220 chr10:102295463 HIF1AN 0.49 6.94 0.35 1.94e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs1814175 0.519 rs10839291 chr11:49514321 G/A cg18944383 chr4:111397179 ENPEP -0.35 -8.09 -0.4 1.08e-14 Height; LIHC cis rs6502050 0.635 rs9889327 chr17:80087839 G/A cg11859384 chr17:80120422 CCDC57 -0.42 -5.74 -0.3 2.06e-8 Life satisfaction; LIHC cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg23172400 chr8:95962367 TP53INP1 -0.37 -8.23 -0.41 3.93e-15 Type 2 diabetes; LIHC cis rs16828019 0.852 rs12759023 chr1:41603978 T/C cg20697417 chr1:41786797 NA 0.35 6.64 0.34 1.24e-10 Intelligence (multi-trait analysis); LIHC cis rs2274273 0.745 rs748017 chr14:55542300 A/G cg01864836 chr14:55583639 NA -0.4 -6.44 -0.33 3.98e-10 Protein biomarker; LIHC cis rs6693567 0.565 rs35784258 chr1:150405882 T/C cg15654264 chr1:150340011 RPRD2 0.49 8.18 0.4 5.55e-15 Migraine; LIHC cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg02782426 chr3:40428986 ENTPD3 0.34 6.18 0.32 1.77e-9 Renal cell carcinoma; LIHC cis rs9399135 0.967 rs11756988 chr6:135347595 A/G cg24558204 chr6:135376177 HBS1L 0.42 6.82 0.35 4.14e-11 Red blood cell count; LIHC cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.6 0.56 3.71e-30 Colorectal cancer; LIHC cis rs11997175 0.646 rs6993892 chr8:33729200 T/C ch.8.33884649F chr8:33765107 NA 0.32 5.96 0.31 6.23e-9 Body mass index; LIHC cis rs7647973 0.922 rs7620024 chr3:49451691 G/A cg07636037 chr3:49044803 WDR6 -0.52 -6.42 -0.33 4.47e-10 Menarche (age at onset); LIHC cis rs9790314 0.934 rs9290074 chr3:160997823 T/C cg04691961 chr3:161091175 C3orf57 -0.39 -6.1 -0.31 2.91e-9 Morning vs. evening chronotype; LIHC cis rs875971 0.825 rs7384021 chr7:66077904 A/G cg18876405 chr7:65276391 NA -0.34 -6.24 -0.32 1.3e-9 Aortic root size; LIHC cis rs875971 0.508 rs10253883 chr7:66061138 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.28 -5.72 -0.3 2.3e-8 Aortic root size; LIHC cis rs12142240 0.698 rs932816 chr1:46859749 G/A cg14993813 chr1:46806288 NSUN4 -0.66 -5.97 -0.31 5.89e-9 Menopause (age at onset); LIHC cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 3.96e-13 Electroencephalogram traits; LIHC trans rs2363709 1.000 rs2363709 chr3:67417105 G/A cg15775005 chr18:9136598 ANKRD12 -0.79 -6.05 -0.31 3.71e-9 IgE levels; LIHC cis rs1577917 0.696 rs2842617 chr6:86309698 C/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.35 -0.32 6.94e-10 Response to antipsychotic treatment; LIHC cis rs7715806 0.509 rs34349 chr5:74944868 A/G cg07671805 chr5:74907694 NA -0.55 -6.5 -0.33 2.77e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10463316 0.779 rs6871318 chr5:150801545 G/A cg03212797 chr5:150827313 SLC36A1 -0.44 -6.43 -0.33 4.36e-10 Metabolite levels (Pyroglutamine); LIHC cis rs2251381 0.741 rs2735966 chr21:30538174 G/A cg24692254 chr21:30365293 RNF160 0.71 10.36 0.49 4.8e-22 Selective IgA deficiency; LIHC cis rs9457247 0.663 rs9457258 chr6:167444254 T/C cg23791538 chr6:167370224 RNASET2 -0.62 -10.71 -0.5 2.77e-23 Crohn's disease; LIHC cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.55e-21 Intelligence (multi-trait analysis); LIHC cis rs4268898 0.608 rs72793980 chr2:24428859 T/C cg06627628 chr2:24431161 ITSN2 -0.63 -8.53 -0.42 4.75e-16 Asthma; LIHC cis rs2859741 0.967 rs592520 chr1:37513503 G/C cg09363841 chr1:37513479 NA -0.2 -6.32 -0.32 8.03e-10 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs7769051 0.808 rs1467404 chr6:133090141 A/G cg22852734 chr6:133119734 C6orf192 -0.94 -9.22 -0.45 3.24e-18 Type 2 diabetes nephropathy; LIHC cis rs11690935 0.918 rs11757 chr2:172641045 C/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.71 -0.69 2.95e-50 Schizophrenia; LIHC cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg18230493 chr5:56204884 C5orf35 -0.42 -5.86 -0.3 1.08e-8 Initial pursuit acceleration; LIHC cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg00684032 chr4:1343700 KIAA1530 0.51 7.43 0.37 8.83e-13 Obesity-related traits; LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg17178900 chr1:205818956 PM20D1 0.66 9.78 0.47 4.36e-20 Menarche (age at onset); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg11702503 chr19:6215254 MLLT1 0.43 6.32 0.32 8.24e-10 Longevity; LIHC cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg12310025 chr6:25882481 NA -0.55 -7.79 -0.39 8.36e-14 Blood metabolite levels; LIHC cis rs1691799 0.836 rs1168334 chr12:66760972 A/G cg16791601 chr12:66731901 HELB -0.48 -10.3 -0.49 7.81e-22 White blood cell count (basophil); LIHC cis rs4664304 0.764 rs2063440 chr2:160800102 A/C cg23995753 chr2:160760732 LY75 -0.38 -5.71 -0.3 2.45e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs8017423 0.967 rs6575120 chr14:90725094 C/T cg04374321 chr14:90722782 PSMC1 0.76 14.51 0.62 1.66e-37 Mortality in heart failure; LIHC cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.16 0.32 2.01e-9 Menopause (age at onset); LIHC cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg20607798 chr8:58055168 NA 0.71 8.55 0.42 4.28e-16 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg08392591 chr16:89556376 ANKRD11 0.53 8.51 0.42 5.4e-16 Multiple myeloma (IgH translocation); LIHC cis rs9303280 1.000 rs9303280 chr17:38074031 T/C cg11212589 chr17:38028394 ZPBP2 -0.33 -6.64 -0.34 1.21e-10 Self-reported allergy; LIHC trans rs1814175 0.645 rs10128563 chr11:50023681 T/C cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC trans rs9858542 1.000 rs1131095 chr3:49714225 T/C cg21659725 chr3:3221576 CRBN -0.54 -6.05 -0.31 3.74e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7927771 0.832 rs10769262 chr11:47411581 G/A cg20135002 chr11:47629003 NA 0.52 8.72 0.43 1.26e-16 Subjective well-being; LIHC cis rs7582180 0.700 rs4851303 chr2:100962064 T/C cg14675211 chr2:100938903 LONRF2 0.55 8.31 0.41 2.24e-15 Intelligence (multi-trait analysis); LIHC cis rs9326248 0.581 rs7120515 chr11:116991926 A/G cg11861562 chr11:117069780 TAGLN 0.4 6.53 0.33 2.4e-10 Blood protein levels; LIHC cis rs4900538 0.819 rs72700604 chr14:102882307 G/A cg18135206 chr14:102964638 TECPR2 -0.71 -11.3 -0.52 2.35e-25 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2302777 0.507 rs1007655 chr17:38111419 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.49 -7.29 -0.37 2.19e-12 Multiple myeloma (hyperdiploidy); LIHC cis rs79057730 0.599 rs35928068 chr7:805363 G/C cg11064039 chr7:766100 PRKAR1B;HEATR2 0.87 9.92 0.47 1.51e-20 Initial pursuit acceleration; LIHC cis rs6988985 0.560 rs4736346 chr8:143951849 G/T cg23373978 chr8:143916136 GML -0.28 -6.03 -0.31 4.15e-9 Plasma androstenedione levels in resected early stage-receptor positive breast cancer; LIHC cis rs8180040 0.966 rs13072802 chr3:47346415 G/C cg27129171 chr3:47204927 SETD2 0.64 10.95 0.51 4.12e-24 Colorectal cancer; LIHC cis rs7165170 0.529 rs3743406 chr15:91161548 A/G cg26821196 chr15:91095069 CRTC3 0.31 5.83 0.3 1.27e-8 Crohn's disease;Inflammatory bowel disease; LIHC cis rs1215050 0.716 rs356549 chr4:98699344 A/G cg05340658 chr4:99064831 C4orf37 0.39 5.78 0.3 1.7e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs1775715 0.966 rs1755067 chr10:32296195 C/T cg14930904 chr10:32216787 ARHGAP12 -0.41 -7.29 -0.37 2.11e-12 Bipolar disorder with mood-incongruent psychosis; LIHC trans rs875971 0.545 rs4718348 chr7:65906576 A/G cg26939375 chr7:64535504 NA 0.41 6.3 0.32 9.23e-10 Aortic root size; LIHC cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs8180040 0.800 rs11130126 chr3:47306894 A/G cg16586182 chr3:47516702 SCAP 0.51 9.01 0.44 1.45e-17 Colorectal cancer; LIHC cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg24549020 chr5:56110836 MAP3K1 0.53 6.92 0.35 2.3e-11 Initial pursuit acceleration; LIHC cis rs599083 0.530 rs689179 chr11:68179166 A/G cg01657329 chr11:68192670 LRP5 0.58 7.84 0.39 5.93e-14 Bone mineral density (spine); LIHC cis rs9916302 0.800 rs8081220 chr17:37473157 A/C cg07936489 chr17:37558343 FBXL20 0.81 12.98 0.57 1.4e-31 Glomerular filtration rate (creatinine); LIHC cis rs12477438 0.520 rs4851187 chr2:99745860 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.23 -24.25 -0.8 2.8299999999999997e-76 Chronic sinus infection; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg04915975 chr3:139063070 MRPS22 -0.41 -6.05 -0.31 3.85e-9 Morning vs. evening chronotype; LIHC cis rs6191 0.904 rs864354 chr5:142634708 T/G cg17617527 chr5:142782415 NR3C1 0.41 5.71 0.3 2.46e-8 Night sleep phenotypes; LIHC trans rs7448080 0.702 rs62371232 chr5:123339637 A/G cg23779626 chr6:33864747 NA -0.59 -6.06 -0.31 3.62e-9 Alcohol dependence (age at onset); LIHC cis rs910316 0.763 rs735452 chr14:75497984 A/G cg08847533 chr14:75593920 NEK9 -0.93 -19.47 -0.73 2.43e-57 Height; LIHC cis rs1559088 0.576 rs10407255 chr19:33581150 A/G cg27124370 chr19:33622961 WDR88 -0.62 -9.29 -0.45 1.8e-18 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1403694 0.515 rs1622922 chr3:186449884 C/T cg12454167 chr3:186435060 KNG1 0.3 7.12 0.36 6.25e-12 Blood protein levels; LIHC cis rs7927592 0.913 rs12294029 chr11:68257059 A/C cg20283391 chr11:68216788 NA -0.5 -7.45 -0.37 7.47e-13 Total body bone mineral density; LIHC cis rs4878497 0.646 rs10758139 chr9:32435676 A/G cg14296220 chr9:32431791 ACO1 0.58 10.02 0.48 6.65e-21 Inflammatory skin disease; LIHC cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg27572855 chr1:25598939 RHD 0.38 8.2 0.41 5.01e-15 Erythrocyte sedimentation rate; LIHC cis rs951366 0.789 rs823094 chr1:205689807 G/T cg07167872 chr1:205819463 PM20D1 -0.55 -7.83 -0.39 6e-14 Menarche (age at onset); LIHC trans rs8002861 0.870 rs4942255 chr13:44451844 A/T cg17145862 chr1:211918768 LPGAT1 -0.52 -9.02 -0.44 1.36e-17 Leprosy; LIHC cis rs6430585 0.583 rs79176913 chr2:136638113 C/A cg07169764 chr2:136633963 MCM6 1.35 23.91 0.79 5.61e-75 Corneal structure; LIHC cis rs4908768 0.859 rs12131717 chr1:8718085 G/A cg20416874 chr1:8611966 RERE 0.48 6.88 0.35 2.82e-11 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2933343 0.679 rs789254 chr3:128574593 A/G cg25356066 chr3:128598488 ACAD9 0.53 7.41 0.37 1e-12 IgG glycosylation; LIHC cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg08677398 chr8:58056175 NA 0.41 6.38 0.33 5.63e-10 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06837242 chr1:19578761 MRTO4;KIAA0090 -0.47 -6.08 -0.31 3.26e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3741404 0.665 rs12418535 chr11:63910980 A/G cg04317338 chr11:64019027 PLCB3 0.49 6.69 0.34 9.11e-11 Platelet count; LIHC cis rs921968 0.643 rs2178019 chr2:219316303 G/A cg02985541 chr2:219472218 PLCD4 0.48 9.11 0.44 7.27e-18 Mean corpuscular hemoglobin concentration; LIHC cis rs10911251 0.546 rs1547714 chr1:183114119 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 3.82e-23 Colorectal cancer; LIHC cis rs12450688 1 rs12450688 chr17:38144229 G/A cg17467752 chr17:38218738 THRA -0.58 -9.93 -0.47 1.4e-20 Sum eosinophil basophil counts; LIHC cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg21448741 chr8:58168803 NA 0.32 6.15 0.32 2.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs4239222 chr17:37696235 A/C cg00129232 chr17:37814104 STARD3 0.42 6.78 0.34 5.34e-11 Glomerular filtration rate (creatinine); LIHC cis rs9303401 0.614 rs68100606 chr17:56500898 G/A cg25039879 chr17:56429692 SUPT4H1 0.79 8.97 0.44 1.99e-17 Cognitive test performance; LIHC cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg02290350 chr8:58132656 NA 0.48 9.92 0.47 1.54e-20 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.806 rs1454649 chr21:45032982 C/T cg04455712 chr21:45112962 RRP1B 0.45 7.69 0.38 1.58e-13 Mean corpuscular volume; LIHC cis rs6461049 0.608 rs3800923 chr7:2184673 A/G cg04267008 chr7:1944627 MAD1L1 -0.44 -6.86 -0.35 3.2e-11 Schizophrenia; LIHC trans rs7178375 1.000 rs7169064 chr15:31210862 C/T cg04373760 chr16:53404718 NA 0.59 7.65 0.38 2e-13 Hypertriglyceridemia; LIHC cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.84 -11.02 -0.51 2.22e-24 Alzheimer's disease; LIHC cis rs7613875 0.578 rs2526749 chr3:50076734 A/G cg24110177 chr3:50126178 RBM5 0.56 9.16 0.44 4.94e-18 Body mass index; LIHC cis rs2549003 0.966 rs839 chr5:131819126 C/T cg02551604 chr5:131831745 NA -0.44 -6.54 -0.33 2.24e-10 Asthma (sex interaction); LIHC cis rs8064024 0.620 rs9923349 chr16:4905124 A/G cg08329684 chr16:4932620 PPL 0.33 5.75 0.3 1.97e-8 Cancer; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg11726039 chr2:208490019 FAM119A -0.36 -6.1 -0.31 2.83e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2280018 0.526 rs2966128 chr16:15153389 G/T cg07549590 chr16:15018862 NA -0.43 -8.06 -0.4 1.28e-14 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs240764 0.604 rs1336242 chr6:101199634 C/T cg12253828 chr6:101329408 ASCC3 0.42 6.47 0.33 3.46e-10 Neuroticism; LIHC cis rs7208859 0.623 rs28627615 chr17:29145817 G/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600806 0.850 rs4970752 chr1:109930852 C/T cg16275483 chr1:110013120 SYPL2 -0.48 -6.09 -0.31 3.02e-9 Intelligence (multi-trait analysis); LIHC cis rs12431939 1.000 rs7140375 chr14:51637242 T/G cg23942311 chr14:51606299 NA -0.35 -5.84 -0.3 1.21e-8 Cancer; LIHC cis rs12477438 0.520 rs13009147 chr2:99803998 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.6 0.64 7.97e-42 Chronic sinus infection; LIHC cis rs7249142 0.562 rs2314035 chr19:19284920 T/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.37 -6.17 -0.32 1.98e-9 IgG glycosylation; LIHC cis rs2163237 0.965 rs10190131 chr2:55983605 A/G cg03859395 chr2:55845619 SMEK2 -0.42 -6.35 -0.32 6.77e-10 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03634887 chr16:66730948 CMTM4 0.42 6.47 0.33 3.35e-10 Cognitive function; LIHC cis rs4555082 0.830 rs2735812 chr14:105727575 A/G cg13114125 chr14:105738426 BRF1 -0.7 -9.3 -0.45 1.77e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs12824058 0.831 rs7310433 chr12:130809289 C/T cg26677194 chr12:130822605 PIWIL1 0.52 7.36 0.37 1.36e-12 Menopause (age at onset); LIHC cis rs9318086 0.753 rs9553094 chr13:24474613 A/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.55 -10.75 -0.5 2.1e-23 Myopia (pathological); LIHC cis rs611744 0.967 rs655722 chr8:109197541 A/T cg18478394 chr8:109455254 TTC35 0.36 6.36 0.33 6.5e-10 Dupuytren's disease; LIHC cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg06497051 chr1:156261200 TMEM79 0.37 5.98 0.31 5.62e-9 Tonsillectomy; LIHC cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.95 9.45 0.45 5.67e-19 Platelet count; LIHC cis rs4665809 0.941 rs1470096 chr2:26311482 T/C cg04944784 chr2:26401820 FAM59B -0.7 -8.7 -0.43 1.44e-16 Gut microbiome composition (summer); LIHC cis rs67478160 0.583 rs12879612 chr14:104233618 T/A cg08213375 chr14:104286397 PPP1R13B 0.65 12.7 0.57 1.59e-30 Schizophrenia; LIHC cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg00800038 chr16:89945340 TCF25 -0.68 -10.63 -0.5 5.19e-23 Skin colour saturation; LIHC cis rs950776 0.518 rs11636131 chr15:78821606 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs847649 0.618 rs6465880 chr7:102515237 T/C cg18108683 chr7:102477205 FBXL13 -0.48 -7.28 -0.37 2.25e-12 Morning vs. evening chronotype; LIHC cis rs4319547 1.000 rs7309390 chr12:123110422 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.14 -0.36 5.59e-12 Body mass index; LIHC cis rs2806561 0.780 rs12409321 chr1:23398065 C/T cg19743168 chr1:23544995 NA -0.37 -6.66 -0.34 1.07e-10 Height; LIHC cis rs7659604 0.728 rs6852923 chr4:122688324 G/A cg20573242 chr4:122745356 CCNA2 0.52 7.89 0.39 4.05e-14 Type 2 diabetes; LIHC cis rs72781680 1.000 rs12616985 chr2:24165511 A/C cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC trans rs7721647 0.810 rs16869794 chr5:90797619 C/T cg10859192 chr12:54071672 ATP5G2 -0.41 -6.07 -0.31 3.34e-9 Breast cancer; LIHC cis rs12579753 1.000 rs2401004 chr12:82214822 T/C cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.48e-9 Resting heart rate; LIHC cis rs868036 0.681 rs2241423 chr15:68086838 G/A cg24579218 chr15:68104479 NA -0.34 -5.94 -0.31 7.12e-9 Restless legs syndrome; LIHC cis rs8072100 1.000 rs7210738 chr17:45757598 G/A cg19378624 chr17:45501242 LOC100272146;C17orf57 0.38 5.91 0.3 8.44e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs6088590 0.965 rs910869 chr20:33292777 C/T cg24642439 chr20:33292090 TP53INP2 0.8 11.47 0.53 5.55e-26 Coronary artery disease; LIHC cis rs3960554 0.529 rs7793844 chr7:75883147 C/T cg01364799 chr7:75623366 TMEM120A -0.46 -6.63 -0.34 1.28e-10 Eotaxin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23097686 chr12:98910128 TMPO;LOC100128191 0.55 7.04 0.36 1.09e-11 Lung function (FEV1/FVC); LIHC cis rs8141529 0.664 rs5762862 chr22:29252732 C/T cg02153584 chr22:29168773 CCDC117 0.43 6.41 0.33 4.97e-10 Lymphocyte counts; LIHC cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg04267008 chr7:1944627 MAD1L1 -0.68 -11.33 -0.52 1.7e-25 Bipolar disorder and schizophrenia; LIHC cis rs1538970 0.962 rs2185549 chr1:45814103 C/T cg24296786 chr1:45957014 TESK2 0.46 6.79 0.34 5.12e-11 Platelet count; LIHC cis rs7072216 0.691 rs7910973 chr10:100166732 G/A cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC cis rs9858542 1.000 rs11718165 chr3:49696797 A/G cg03060546 chr3:49711283 APEH -0.6 -8.14 -0.4 7.32e-15 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7520050 0.966 rs61102033 chr1:46382441 G/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.37e-8 Red blood cell count;Reticulocyte count; LIHC trans rs11098499 0.863 rs6534141 chr4:120485223 A/T cg25214090 chr10:38739885 LOC399744 0.57 8.97 0.44 2.03e-17 Corneal astigmatism; LIHC cis rs35892873 0.501 rs4299436 chr3:126096047 C/T cg15490784 chr3:126061950 KLF15 -0.4 -5.85 -0.3 1.15e-8 Male-pattern baldness; LIHC cis rs919433 0.680 rs3792159 chr2:198403697 A/G cg03934865 chr2:198174659 NA -0.54 -8.14 -0.4 7.61e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2204008 0.604 rs11172718 chr12:38069819 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.51 0.49 1.47e-22 Bladder cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05880217 chr17:79846343 THOC4 -0.39 -6.05 -0.31 3.81e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9640161 0.789 rs34311995 chr7:150059255 T/C cg17279839 chr7:150038598 RARRES2 0.39 7.85 0.39 5.4e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs826838 1.000 rs10875991 chr12:39108886 G/C cg26384229 chr12:38710491 ALG10B 0.89 11.69 0.53 9.04e-27 Heart rate; LIHC cis rs7618501 0.633 rs6446193 chr3:50059758 T/C cg24110177 chr3:50126178 RBM5 0.48 7.79 0.39 8.07e-14 Intelligence (multi-trait analysis); LIHC cis rs7927592 0.956 rs7102273 chr11:68385579 T/C cg20283391 chr11:68216788 NA -0.51 -7.61 -0.38 2.73e-13 Total body bone mineral density; LIHC trans rs6598955 0.585 rs12138111 chr1:26590432 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.57 -0.42 3.61e-16 Obesity-related traits; LIHC cis rs11122272 0.735 rs2739506 chr1:231529183 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs7208859 0.623 rs73269945 chr17:29108759 G/A cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs798766 1.000 rs4865463 chr4:1742400 T/C cg21231739 chr4:1642635 FAM53A -0.38 -6.1 -0.31 2.82e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs9393692 0.875 rs2142703 chr6:26289605 A/G cg00631329 chr6:26305371 NA -0.42 -6.96 -0.35 1.76e-11 Educational attainment; LIHC cis rs7208859 0.623 rs9890855 chr17:29111707 G/C cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs832187 0.594 rs832197 chr3:63884292 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.43 6.11 0.31 2.66e-9 Schizophrenia; LIHC cis rs6445797 0.855 rs7646924 chr3:56570947 G/C cg13792233 chr3:56591045 CCDC66 -0.39 -5.73 -0.3 2.17e-8 Gastritis; LIHC cis rs12701220 0.522 rs868833 chr7:1054973 C/G cg26769984 chr7:1090371 C7orf50 0.44 5.97 0.31 5.83e-9 Bronchopulmonary dysplasia; LIHC cis rs12474201 1.000 rs12474201 chr2:46921285 C/T cg06386533 chr2:46925753 SOCS5 0.52 6.2 0.32 1.66e-9 Height; LIHC cis rs6951245 0.882 rs56048221 chr7:1092533 A/G cg24642844 chr7:1081250 C7orf50 -0.8 -8.38 -0.41 1.4e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg06481639 chr22:41940642 POLR3H 0.69 7.12 0.36 6.52e-12 Vitiligo; LIHC trans rs11098499 0.629 rs28369518 chr4:120271630 T/C cg25214090 chr10:38739885 LOC399744 0.44 7.28 0.37 2.26e-12 Corneal astigmatism; LIHC cis rs17106184 1.000 rs12071359 chr1:51388895 G/A cg07174182 chr1:51127561 FAF1 -0.76 -8.7 -0.43 1.44e-16 Type 2 diabetes; LIHC cis rs801193 0.591 rs721717 chr7:66130292 G/T cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs911119 0.955 rs17751897 chr20:23592714 T/C cg16589663 chr20:23618590 CST3 0.72 7.62 0.38 2.6e-13 Chronic kidney disease; LIHC cis rs2549003 1.000 rs2070727 chr5:131820275 C/A cg02551604 chr5:131831745 NA -0.44 -6.54 -0.33 2.24e-10 Asthma (sex interaction); LIHC cis rs769267 0.930 rs2099334 chr19:19578450 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 8.0 0.4 1.99e-14 Tonsillectomy; LIHC cis rs6665290 0.904 rs6664955 chr1:227183434 T/C cg10327440 chr1:227177885 CDC42BPA -1.18 -26.78 -0.82 6.04e-86 Myeloid white cell count; LIHC cis rs7072216 0.763 rs2274246 chr10:100175060 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -6.38 -0.33 5.7e-10 Metabolite levels; LIHC cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg07414643 chr4:187882934 NA 0.23 5.73 0.3 2.19e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs738322 0.839 rs2413505 chr22:38592967 G/A cg25457927 chr22:38595422 NA 0.33 8.32 0.41 2.08e-15 Cutaneous nevi; LIHC cis rs7106204 0.514 rs10834307 chr11:24272516 G/A ch.11.24196551F chr11:24239977 NA -0.77 -10.29 -0.49 7.99e-22 Response to Homoharringtonine (cytotoxicity); LIHC cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg02353165 chr6:42928485 GNMT 1.0 17.15 0.68 5.23e-48 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg26818010 chr10:134567672 INPP5A -0.78 -9.25 -0.45 2.43e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs798554 0.757 rs1182179 chr7:2873648 A/G cg04166393 chr7:2884313 GNA12 0.47 6.27 0.32 1.06e-9 Height; LIHC cis rs3733606 1.000 rs3733606 chr4:6883012 A/G cg05012661 chr4:6891264 NA -0.35 -5.79 -0.3 1.58e-8 Platelet count; LIHC cis rs6831352 0.589 rs2924584 chr4:99988208 A/G cg13256891 chr4:100009986 ADH5 0.39 5.73 0.3 2.19e-8 Alcohol dependence; LIHC cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 12.25 0.55 7.28e-29 Alzheimer's disease; LIHC cis rs8060686 0.545 rs3815173 chr16:68160289 T/G cg09835421 chr16:68378352 PRMT7 -0.54 -6.13 -0.31 2.41e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs916888 0.773 rs199447 chr17:44812188 C/T cg07870213 chr5:140052090 DND1 1.03 10.58 0.5 7.82e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs600806 0.850 rs6537757 chr1:109936682 G/A cg23091122 chr1:110024289 SYPL2 -0.45 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC cis rs2153535 0.580 rs6597332 chr6:8504748 C/G cg23788917 chr6:8435910 SLC35B3 0.6 8.42 0.41 1.05e-15 Motion sickness; LIHC cis rs4474465 0.915 rs12273367 chr11:78173835 A/T cg02023728 chr11:77925099 USP35 0.35 6.26 0.32 1.13e-9 Alzheimer's disease (survival time); LIHC cis rs2421770 0.530 rs3901811 chr11:35365675 C/T cg13971030 chr11:35366721 SLC1A2 -0.45 -7.59 -0.38 3.02e-13 Staphylococcus aureus nasal carriage (persistent); LIHC cis rs743757 1.000 rs2282754 chr3:50436827 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.5 7.74 0.39 1.17e-13 Diastolic blood pressure; LIHC cis rs6066825 0.555 rs4810849 chr20:47289944 C/T cg18078177 chr20:47281410 PREX1 0.41 6.79 0.34 4.97e-11 Colorectal cancer; LIHC cis rs847649 0.732 rs56269620 chr7:102489456 A/G cg18108683 chr7:102477205 FBXL13 -0.51 -8.1 -0.4 9.83e-15 Morning vs. evening chronotype; LIHC cis rs34888975 1 rs34888975 chr16:1695896 T/TA cg09065629 chr16:1709722 CRAMP1L 0.85 10.15 0.48 2.46e-21 Snoring; LIHC cis rs6754311 0.550 rs10173394 chr2:136522675 C/T cg07169764 chr2:136633963 MCM6 -0.68 -9.8 -0.47 3.83e-20 Mosquito bite size; LIHC cis rs6942756 1.000 rs12111832 chr7:128889025 G/C cg02491457 chr7:128862824 NA -0.72 -11.32 -0.52 1.84e-25 White matter hyperintensity burden; LIHC cis rs11676348 0.774 rs13397673 chr2:219047782 A/G cg20019365 chr2:219134978 PNKD;AAMP -0.44 -5.86 -0.3 1.08e-8 Ulcerative colitis; LIHC cis rs950776 0.518 rs952215 chr15:78819153 C/T cg22563815 chr15:78856949 CHRNA5 -0.36 -6.62 -0.34 1.36e-10 Sudden cardiac arrest; LIHC cis rs7937682 0.632 rs4936834 chr11:111764017 T/A cg09085632 chr11:111637200 PPP2R1B 0.92 12.98 0.57 1.38e-31 Primary sclerosing cholangitis; LIHC cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg23205692 chr1:25664452 TMEM50A 0.39 6.21 0.32 1.54e-9 Plateletcrit;Mean corpuscular volume; LIHC cis rs68170813 0.641 rs75254991 chr7:106938903 C/T cg02696742 chr7:106810147 HBP1 -0.5 -5.81 -0.3 1.42e-8 Coronary artery disease; LIHC cis rs4466137 0.953 rs974023 chr5:83014848 T/C cg16102102 chr5:83017553 HAPLN1 -0.58 -8.37 -0.41 1.45e-15 Prostate cancer; LIHC cis rs3857067 0.806 rs4693375 chr4:95133241 C/A cg11021082 chr4:95130006 SMARCAD1 -0.44 -7.75 -0.39 1.06e-13 QT interval; LIHC cis rs13217239 0.646 rs35691005 chr6:26972070 A/G cg12292205 chr6:26970375 C6orf41 0.45 7.76 0.39 1.02e-13 Schizophrenia; LIHC cis rs2016586 0.796 rs972153 chr22:36100410 C/A cg26342177 chr22:36113512 APOL5 -0.43 -7.1 -0.36 7.2e-12 Body mass index; LIHC cis rs12586317 0.547 rs115019197 chr14:35503764 G/A cg16230307 chr14:35515116 FAM177A1 0.79 13.38 0.59 4.02e-33 Psoriasis; LIHC trans rs9914544 0.545 rs12942794 chr17:18767217 A/C cg21372672 chr17:16614065 CCDC144A -0.27 -6.58 -0.34 1.8e-10 Educational attainment (years of education); LIHC cis rs7106204 0.590 rs7114724 chr11:24239976 A/G ch.11.24196551F chr11:24239977 NA 0.81 11.73 0.54 5.97e-27 Response to Homoharringtonine (cytotoxicity); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg20609344 chr11:101785659 KIAA1377;ANGPTL5 -0.48 -6.05 -0.31 3.81e-9 Lung function (FEV1); LIHC cis rs17428076 0.514 rs3821095 chr2:172684006 A/G cg13550731 chr2:172543902 DYNC1I2 -0.5 -8.42 -0.41 1.08e-15 Myopia; LIHC cis rs2439831 0.867 rs689616 chr15:43761901 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.83 0.43 5.6e-17 Lung cancer in ever smokers; LIHC trans rs11689435 0.925 rs4278910 chr2:218349910 T/G cg13544946 chr9:35729779 TLN1 -0.42 -6.14 -0.32 2.24e-9 Metabolite levels (MHPG); LIHC trans rs459571 0.959 rs416390 chr9:136908549 C/G cg09836344 chr4:1243392 C4orf42;CTBP1 0.57 8.78 0.43 8.14e-17 Platelet distribution width; LIHC cis rs3806843 0.966 rs2563255 chr5:140142547 T/C cg26395211 chr5:140044315 WDR55 0.4 5.97 0.31 5.79e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg26338869 chr17:61819248 STRADA 0.61 8.86 0.43 4.31e-17 Prudent dietary pattern; LIHC trans rs7428850 0.803 rs12638750 chr3:24087133 T/C cg07387471 chr17:34795793 TBC1D3C 0.61 6.07 0.31 3.38e-9 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; LIHC cis rs7395581 0.959 rs2167079 chr11:47270255 C/T cg26139080 chr11:47293733 MADD -0.49 -8.26 -0.41 3.31e-15 HDL cholesterol; LIHC cis rs1008375 0.966 rs3775925 chr4:17588437 A/G cg16339924 chr4:17578868 LAP3 0.46 6.3 0.32 9.36e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs12477438 0.798 rs17708218 chr2:99696284 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.89 -0.51 6.33e-24 Chronic sinus infection; LIHC cis rs875971 0.830 rs4718358 chr7:65973668 T/C cg18252515 chr7:66147081 NA -0.41 -5.85 -0.3 1.17e-8 Aortic root size; LIHC cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.81 12.71 0.57 1.41e-30 Total body bone mineral density; LIHC cis rs875971 0.545 rs75577046 chr7:65958716 A/G cg11764359 chr7:65958608 NA 0.58 8.22 0.41 4.2e-15 Aortic root size; LIHC cis rs34375054 0.573 rs12581813 chr12:125656402 A/G cg25124228 chr12:125621409 AACS -0.43 -6.6 -0.34 1.59e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs2762353 0.603 rs10946798 chr6:25781853 T/G cg12310025 chr6:25882481 NA 0.48 6.41 0.33 4.91e-10 Blood metabolite levels; LIHC cis rs7772486 0.840 rs11155451 chr6:146422524 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.72 0.3 2.36e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs7481584 0.624 rs375579 chr11:3065300 G/C cg25174290 chr11:3078921 CARS -0.41 -6.0 -0.31 4.9e-9 Calcium levels; LIHC cis rs10193935 0.901 rs7601905 chr2:42494144 A/G cg27598129 chr2:42591480 NA -0.68 -10.48 -0.49 1.78e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.6 -0.46 1.83e-19 Initial pursuit acceleration; LIHC cis rs875971 0.862 rs13536 chr7:66019190 G/A cg11764359 chr7:65958608 NA -0.78 -13.63 -0.59 4.46e-34 Aortic root size; LIHC cis rs7829975 0.840 rs572366 chr8:8578794 A/T cg18904891 chr8:8559673 CLDN23 0.4 5.77 0.3 1.77e-8 Mood instability; LIHC cis rs6582630 0.554 rs8189625 chr12:38401177 C/T cg26384229 chr12:38710491 ALG10B -0.47 -6.15 -0.32 2.17e-9 Drug-induced liver injury (flucloxacillin); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg18334142 chr5:158636736 NA 0.47 6.43 0.33 4.27e-10 Lung function (FEV1/FVC); LIHC trans rs9858542 1.000 rs9812791 chr3:49682311 G/A cg21659725 chr3:3221576 CRBN -0.57 -6.41 -0.33 4.91e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1144333 0.655 rs76794487 chr1:76384055 G/A cg03433033 chr1:76189801 ACADM 0.52 7.28 0.37 2.26e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs2439831 0.702 rs495175 chr15:43798684 C/G cg15269541 chr15:43626905 ADAL -0.3 -5.78 -0.3 1.7e-8 Lung cancer in ever smokers; LIHC cis rs6762477 0.748 rs2073726 chr3:50223593 T/A cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.52 -7.96 -0.4 2.61e-14 Menarche (age at onset); LIHC cis rs9303280 0.837 rs907092 chr17:37922259 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.38 -5.86 -0.3 1.11e-8 Self-reported allergy; LIHC cis rs11711311 1.000 rs3773682 chr3:113520576 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.13 0.4 8.21e-15 IgG glycosylation; LIHC cis rs2404602 1.000 rs4886818 chr15:76880939 G/A cg03037974 chr15:76606532 NA 0.71 13.6 0.59 5.9e-34 Blood metabolite levels; LIHC cis rs7909074 1.000 rs10751361 chr10:45398186 C/A cg04218760 chr10:45406644 TMEM72 -0.24 -7.36 -0.37 1.36e-12 Mean corpuscular volume; LIHC cis rs1005277 0.602 rs1780141 chr10:38504299 T/C cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs5769765 0.865 rs3788730 chr22:50244695 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.67 8.71 0.43 1.29e-16 Schizophrenia; LIHC cis rs10838687 1.000 rs6485751 chr11:47336442 G/C cg26139080 chr11:47293733 MADD -0.44 -6.34 -0.32 7.29e-10 Proinsulin levels; LIHC cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs9814567 0.806 rs4245904 chr3:134321808 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4517514 0.509 rs4385851 chr11:89870750 C/T cg05041596 chr11:89867385 NAALAD2 0.4 6.4 0.33 5.17e-10 Trans fatty acid levels; LIHC cis rs2075371 0.966 rs722657 chr7:133994956 T/C cg20476274 chr7:133979776 SLC35B4 0.74 12.13 0.55 2.1e-28 Mean platelet volume; LIHC cis rs9325144 0.505 rs1906262 chr12:38653605 A/G cg26384229 chr12:38710491 ALG10B 0.47 7.4 0.37 1.07e-12 Morning vs. evening chronotype; LIHC cis rs8062405 0.540 rs193628 chr16:28582142 G/T cg00204512 chr16:28754710 NA -0.3 -5.83 -0.3 1.3e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg07424592 chr7:64974309 NA -0.8 -9.25 -0.45 2.55e-18 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg11764359 chr7:65958608 NA 0.58 6.03 0.31 4.22e-9 Diabetic kidney disease; LIHC cis rs6831352 0.918 rs13133633 chr4:100058697 C/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs769267 0.965 rs8103496 chr19:19386015 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC cis rs916888 0.773 rs199448 chr17:44809001 A/G cg01570182 chr17:44337453 NA 1.01 10.14 0.48 2.6e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2404602 0.692 rs7350777 chr15:76985441 G/A cg03037974 chr15:76606532 NA 0.74 14.58 0.62 8.72e-38 Blood metabolite levels; LIHC cis rs72634258 0.503 rs697675 chr1:7838113 A/C cg26816564 chr1:7831052 VAMP3 0.68 6.92 0.35 2.19e-11 Inflammatory bowel disease; LIHC cis rs3008870 0.755 rs2065002 chr1:67487119 A/C cg08660285 chr1:67390436 MIER1;WDR78 -0.62 -10.02 -0.48 6.88e-21 Lymphocyte percentage of white cells; LIHC cis rs611744 0.967 rs613644 chr8:109188994 G/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs769267 0.896 rs10405625 chr19:19579046 T/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.08 0.31 3.16e-9 Tonsillectomy; LIHC cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.75 0.39 1.07e-13 Prudent dietary pattern; LIHC cis rs12477438 0.520 rs6743355 chr2:99732360 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 22.68 0.78 3.75e-70 Chronic sinus infection; LIHC cis rs7267979 0.565 rs3752273 chr20:25594783 A/T cg24626310 chr20:25276739 ABHD12;PYGB -0.43 -5.92 -0.31 7.68e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs35110281 0.607 rs4819212 chr21:44977455 G/A cg21573476 chr21:45109991 RRP1B -0.53 -9.85 -0.47 2.63e-20 Mean corpuscular volume; LIHC cis rs765787 0.530 rs13329228 chr15:45533017 C/T cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.76 -0.3 1.86e-8 Uric acid levels; LIHC cis rs59574136 1 rs59574136 chr7:2036460 T/C cg18279126 chr7:2041391 MAD1L1 0.38 6.42 0.33 4.44e-10 Autism spectrum disorder or schizophrenia; LIHC cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6918391 chr6:8461178 A/C cg23788917 chr6:8435910 SLC35B3 0.61 8.65 0.42 1.99e-16 Motion sickness; LIHC cis rs4853036 0.857 rs1048139 chr2:70131791 T/A cg02498382 chr2:70120550 SNRNP27 -0.4 -6.28 -0.32 1.02e-9 Colorectal or endometrial cancer; LIHC cis rs1949733 0.656 rs2688243 chr4:8436286 A/G cg11789530 chr4:8429930 ACOX3 0.73 10.95 0.51 4.14e-24 Response to antineoplastic agents; LIHC cis rs7772486 0.790 rs9399571 chr6:146282061 A/G cg23711669 chr6:146136114 FBXO30 -0.63 -10.89 -0.51 6.6e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs28735056 0.967 rs11660941 chr18:77630600 G/C cg20368463 chr18:77673604 PQLC1 -0.38 -6.67 -0.34 1.05e-10 Schizophrenia; LIHC cis rs12479064 0.724 rs3792150 chr2:100041849 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -8.9 -0.43 3.35e-17 Chronic sinus infection; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg18502306 chr4:8376764 ACOX3 -0.39 -6.14 -0.32 2.29e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs9929218 0.911 rs1075959 chr16:68832750 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.57 -8.13 -0.4 8.12e-15 Colorectal cancer; LIHC cis rs6750047 0.585 rs168054 chr2:38260282 C/G cg07380506 chr2:38303506 CYP1B1 -0.57 -7.25 -0.36 2.83e-12 Cutaneous malignant melanoma;Melanoma; LIHC cis rs3015497 0.967 rs8018308 chr14:51122633 T/C cg09863266 chr14:51125203 SAV1 -0.4 -6.46 -0.33 3.64e-10 Mean platelet volume; LIHC cis rs36051895 0.559 rs72701680 chr9:5207294 A/T cg02405213 chr9:5042618 JAK2 -0.61 -10.53 -0.49 1.19e-22 Pediatric autoimmune diseases; LIHC cis rs10484885 0.775 rs17584945 chr6:90512776 T/C cg13799429 chr6:90582589 CASP8AP2 -0.73 -6.52 -0.33 2.47e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs6504950 0.745 rs12949718 chr17:52981853 A/G cg10237252 chr17:52977213 TOM1L1 0.34 6.07 0.31 3.35e-9 Breast cancer; LIHC cis rs7534824 0.625 rs61780332 chr1:101484733 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.75 6.98 0.35 1.57e-11 Refractive astigmatism; LIHC trans rs911119 0.657 rs13039144 chr20:23633755 A/G cg23114964 chr1:42217077 HIVEP3 0.41 6.18 0.32 1.79e-9 Chronic kidney disease; LIHC cis rs6951245 0.938 rs11764937 chr7:1092074 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.04 0.31 4.11e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs5769707 0.967 rs2051626 chr22:50008973 G/A cg01652190 chr22:50026171 C22orf34 -0.3 -6.92 -0.35 2.28e-11 Monocyte count;Monocyte percentage of white cells; LIHC cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg09455208 chr3:40491958 NA 0.4 8.24 0.41 3.63e-15 Renal cell carcinoma; LIHC cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg13409248 chr3:40428643 ENTPD3 0.4 6.55 0.33 2.16e-10 Renal cell carcinoma; LIHC cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg17178900 chr1:205818956 PM20D1 0.66 9.92 0.47 1.53e-20 Menarche (age at onset); LIHC cis rs6461049 0.638 rs1859993 chr7:2183702 A/G cg02951883 chr7:2050386 MAD1L1 -0.52 -8.16 -0.4 6.68e-15 Schizophrenia; LIHC cis rs926392 0.640 rs1007913 chr20:37693592 G/A cg16355469 chr20:37678765 NA 0.45 6.58 0.34 1.75e-10 Dialysis-related mortality; LIHC cis rs2073300 0.609 rs6137927 chr20:23372513 A/G cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7659604 1.000 rs6814995 chr4:122664963 A/T cg19748678 chr4:122722346 EXOSC9 -0.35 -5.84 -0.3 1.25e-8 Type 2 diabetes; LIHC cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg24531977 chr5:56204891 C5orf35 -0.68 -9.87 -0.47 2.22e-20 Initial pursuit acceleration; LIHC cis rs244293 0.831 rs7209029 chr17:53173046 A/G cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.55 0.38 4.05e-13 Menarche (age at onset); LIHC cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg13271783 chr10:134563150 INPP5A -0.61 -7.26 -0.37 2.69e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg01516881 chr6:292596 DUSP22 -0.57 -7.6 -0.38 2.86e-13 Menopause (age at onset); LIHC cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg25072359 chr17:41440525 NA 0.39 6.28 0.32 9.99e-10 Menopause (age at onset); LIHC cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg13047869 chr3:10149882 C3orf24 0.51 6.07 0.31 3.42e-9 Alzheimer's disease; LIHC cis rs4853012 0.941 rs7571083 chr2:74342260 C/G cg20891558 chr2:74357851 NA 0.81 16.52 0.67 1.76e-45 Gestational age at birth (maternal effect); LIHC cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs3020736 0.500 rs6002601 chr22:42489058 A/T cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs17102423 0.963 rs35002541 chr14:65598704 G/A cg11161011 chr14:65562177 MAX -0.44 -6.0 -0.31 5.09e-9 Obesity-related traits; LIHC cis rs2153535 0.580 rs7748455 chr6:8453625 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.68 0.42 1.65e-16 Motion sickness; LIHC cis rs7633770 0.643 rs1581325 chr3:46691866 T/C cg11219411 chr3:46661640 NA -0.35 -5.85 -0.3 1.14e-8 Coronary artery disease; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg14729855 chr6:34204698 HMGA1 0.51 6.45 0.33 3.93e-10 Glycated hemoglobin levels; LIHC cis rs10751667 0.666 rs7396509 chr11:956761 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.09 0.48 4.1e-21 Alzheimer's disease (late onset); LIHC trans rs12478296 1.000 rs56136197 chr2:243043877 T/C cg01596870 chr19:55963115 NA -0.63 -8.3 -0.41 2.39e-15 Obesity-related traits; LIHC cis rs11122272 0.701 rs2474628 chr1:231526000 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs2637266 0.935 rs1907323 chr10:78336015 C/T cg18941641 chr10:78392320 NA 0.28 6.18 0.32 1.79e-9 Pulmonary function; LIHC cis rs477692 0.870 rs475250 chr10:131412558 C/G cg19680672 chr10:131412579 MGMT -0.42 -6.55 -0.33 2.05e-10 Response to temozolomide; LIHC cis rs10791323 0.602 rs7946895 chr11:133733893 T/C cg06766960 chr11:133703094 NA -0.62 -9.72 -0.47 6.83e-20 Childhood ear infection; LIHC cis rs1904096 0.506 rs3113863 chr4:95147827 G/C cg11021082 chr4:95130006 SMARCAD1 -0.48 -9.0 -0.44 1.62e-17 Type 2 diabetes; LIHC trans rs6759952 0.649 rs1382435 chr2:218296003 A/G cg05170863 chr8:109261119 EIF3E 0.44 6.15 0.32 2.18e-9 Thyroid cancer; LIHC cis rs9811920 0.638 rs10936008 chr3:99686665 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -7.19 -0.36 4.09e-12 Axial length; LIHC cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.18e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs11098499 0.562 rs2389879 chr4:120557684 G/A cg25214090 chr10:38739885 LOC399744 -0.44 -7.15 -0.36 5.31e-12 Corneal astigmatism; LIHC cis rs66573146 0.831 rs67702333 chr4:6983040 C/G cg15105060 chr4:7024189 TBC1D14 -0.72 -6.04 -0.31 3.96e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1552244 0.882 rs13099136 chr3:10031431 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.66 -10.32 -0.49 6.5e-22 Alzheimer's disease; LIHC trans rs10028773 0.600 rs4001390 chr4:120265783 G/C cg25214090 chr10:38739885 LOC399744 0.44 7.16 0.36 5.01e-12 Educational attainment; LIHC cis rs7772486 0.875 rs9322045 chr6:146384950 C/G cg05347473 chr6:146136440 FBXO30 0.34 5.72 0.3 2.31e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2629540 0.924 rs1545910 chr10:126428145 G/C cg08799069 chr10:126477246 METTL10 -0.49 -7.73 -0.39 1.23e-13 Cocaine dependence; LIHC cis rs3960554 0.569 rs10954750 chr7:75664921 C/G cg16489192 chr7:75678113 MDH2;STYXL1 0.37 5.76 0.3 1.86e-8 Eotaxin levels; LIHC cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 9.99 0.48 8.86e-21 Platelet count; LIHC cis rs12477438 0.520 rs2516835 chr2:99779131 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 10.0 0.48 8.1899999999999992e-21 Chronic sinus infection; LIHC cis rs7581030 0.958 rs6761251 chr2:71521191 T/G cg07678644 chr2:71558969 ZNF638 0.46 6.64 0.34 1.25e-10 Testicular germ cell tumor; LIHC cis rs7911264 0.628 rs7078243 chr10:94414263 A/C cg00519463 chr10:94352821 KIF11 -0.46 -6.33 -0.32 7.82e-10 Inflammatory bowel disease; LIHC cis rs9399135 0.935 rs949547 chr6:135343499 C/G cg22676075 chr6:135203613 NA 0.39 6.32 0.32 8.12e-10 Red blood cell count; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg24209194 chr3:40518798 ZNF619 -0.66 -10.09 -0.48 4.03e-21 Renal cell carcinoma; LIHC cis rs754466 0.651 rs11813532 chr10:79637991 T/C cg17075019 chr10:79541650 NA -0.75 -11.45 -0.53 6.58e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs34172651 0.517 rs189919 chr16:24737741 G/A cg00339695 chr16:24857497 SLC5A11 -0.68 -9.71 -0.47 7.32e-20 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.735 rs702394 chr5:140086786 A/G cg26395211 chr5:140044315 WDR55 0.41 5.97 0.31 5.94e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.57 8.83 0.43 5.5e-17 Height; LIHC cis rs9388451 0.807 rs1268070 chr6:126041164 A/G cg05901451 chr6:126070800 HEY2 -0.71 -14.29 -0.61 1.24e-36 Brugada syndrome; LIHC cis rs72627123 0.867 rs17093884 chr14:74482039 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.9 9.53 0.46 2.97e-19 Morning vs. evening chronotype; LIHC cis rs12291225 0.679 rs11238 chr11:14288128 A/C cg19336497 chr11:14380999 RRAS2 0.65 12.85 0.57 4.18e-31 Sense of smell; LIHC cis rs311392 0.525 rs311391 chr8:55103542 T/G cg11783602 chr8:55087084 NA -0.31 -6.21 -0.32 1.53e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs9911578 1.000 rs172565 chr17:56808996 A/T cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.28e-16 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.692 rs4886829 chr15:77091182 G/T cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.96e-38 Blood metabolite levels; LIHC cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg11062466 chr8:58055876 NA 0.5 6.9 0.35 2.54e-11 Developmental language disorder (linguistic errors); LIHC cis rs3812831 0.599 rs428637 chr13:114927139 T/G cg08824895 chr13:115047677 UPF3A 0.41 5.88 0.3 1e-8 Schizophrenia; LIHC trans rs11098499 0.865 rs4001305 chr4:120359236 G/T cg25214090 chr10:38739885 LOC399744 0.59 9.7 0.46 8.2e-20 Corneal astigmatism; LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg26939375 chr7:64535504 NA -0.43 -7.33 -0.37 1.67e-12 Calcium levels; LIHC cis rs3008870 0.583 rs2031495 chr1:67421714 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.87 13.18 0.58 2.36e-32 Lymphocyte percentage of white cells; LIHC trans rs561341 0.843 rs2028067 chr17:30239698 T/C cg20587970 chr11:113659929 NA -0.6 -7.36 -0.37 1.4e-12 Hip circumference adjusted for BMI; LIHC cis rs7208859 0.673 rs61223749 chr17:29163747 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9790314 1.000 rs9850455 chr3:161017192 G/A cg04691961 chr3:161091175 C3orf57 -0.33 -5.75 -0.3 1.93e-8 Morning vs. evening chronotype; LIHC cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg11987759 chr7:65425863 GUSB -0.39 -6.15 -0.32 2.22e-9 Calcium levels; LIHC cis rs8077889 0.871 rs11079838 chr17:41898971 G/A cg26893861 chr17:41843967 DUSP3 0.95 11.14 0.52 8.8e-25 Triglycerides; LIHC cis rs3820068 0.581 rs72645871 chr1:15926142 G/A cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs116095464 0.558 rs6872854 chr5:209038 G/T cg22857025 chr5:266934 NA -1.54 -18.37 -0.7 6.36e-53 Breast cancer; LIHC cis rs965469 1.000 rs6037562 chr20:3326141 A/C cg25506879 chr20:3388711 C20orf194 -0.58 -6.98 -0.35 1.59e-11 IFN-related cytopenia; LIHC trans rs11722228 0.521 rs56403947 chr4:10112529 T/G cg26043149 chr18:55253948 FECH 0.99 14.04 0.6 1.09e-35 Gout;Urate levels;Serum uric acid levels; LIHC cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg10802521 chr3:52805072 NEK4 -0.41 -6.57 -0.33 1.9e-10 Bipolar disorder; LIHC cis rs7395581 0.918 rs3816725 chr11:47305669 T/G cg26139080 chr11:47293733 MADD -0.5 -8.38 -0.41 1.37e-15 HDL cholesterol; LIHC trans rs4824093 0.610 rs73443923 chr22:50285348 C/T cg09872104 chr7:134855509 C7orf49 -0.83 -6.55 -0.33 2.17e-10 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs12497850 0.931 rs4974080 chr3:49030828 A/C cg06212747 chr3:49208901 KLHDC8B 0.56 6.93 0.35 2.08e-11 Parkinson's disease; LIHC cis rs2016586 0.929 rs8136655 chr22:36111820 G/A cg26342177 chr22:36113512 APOL5 -0.38 -6.3 -0.32 9.32e-10 Body mass index; LIHC cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg12463550 chr7:65579703 CRCP 0.68 7.32 0.37 1.82e-12 Diabetic kidney disease; LIHC cis rs8078723 0.933 rs4794822 chr17:38156712 C/T cg17467752 chr17:38218738 THRA 0.76 13.98 0.6 1.96e-35 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6433857 0.657 rs2368178 chr2:181501938 T/C cg23363182 chr2:181467187 NA -0.36 -5.85 -0.3 1.12e-8 Body mass index; LIHC cis rs509477 0.690 rs273354 chr18:32598235 T/C cg23791764 chr18:32556832 MAPRE2 0.46 6.19 0.32 1.77e-9 Cerebrospinal fluid AB1-42 levels; LIHC cis rs2274273 1.000 rs74617736 chr14:55620919 C/T cg01864836 chr14:55583639 NA -0.35 -5.82 -0.3 1.36e-8 Protein biomarker; LIHC cis rs74181299 0.533 rs984748 chr2:65369964 A/G cg05010058 chr2:65284262 CEP68 -0.36 -5.73 -0.3 2.17e-8 Pulse pressure; LIHC cis rs10861342 1.000 rs12229846 chr12:105553066 A/C cg23923672 chr12:105501055 KIAA1033 0.65 7.57 0.38 3.52e-13 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24063238 chr17:56085336 SFRS1 0.42 6.08 0.31 3.15e-9 Cognitive function; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg18538332 chr22:24372958 LOC391322 -0.65 -9.98 -0.47 9.37e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4665809 0.941 rs1434079 chr2:26284670 C/G cg04944784 chr2:26401820 FAM59B -0.66 -8.22 -0.41 4.16e-15 Gut microbiome composition (summer); LIHC trans rs4566357 0.595 rs6707286 chr2:227911400 A/G cg16088116 chr21:44841560 SIK1 -0.4 -6.2 -0.32 1.6e-9 Coronary artery disease; LIHC trans rs10095849 0.576 rs13260129 chr8:39477848 A/C cg23465891 chr13:113420166 ATP11A -0.4 -6.5 -0.33 2.86e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs7520050 0.898 rs4660885 chr1:46243756 C/T cg03146154 chr1:46216737 IPP -0.4 -6.75 -0.34 6.52e-11 Red blood cell count;Reticulocyte count; LIHC cis rs10426930 0.607 rs56251289 chr19:5042732 C/A cg18473234 chr19:5097819 KDM4B 0.58 6.74 0.34 6.81e-11 Monocyte percentage of white cells; LIHC cis rs7129556 0.520 rs12290511 chr11:77266663 T/G cg03570279 chr11:77446074 RSF1 -0.35 -6.5 -0.33 2.78e-10 Weight loss (gastric bypass surgery); LIHC cis rs892961 0.932 rs9646396 chr17:75416755 G/A cg01320579 chr17:75405842 SEPT9 0.53 6.91 0.35 2.36e-11 Airflow obstruction; LIHC cis rs35306767 0.903 rs35567307 chr10:915804 G/C cg20503657 chr10:835505 NA 1.07 12.48 0.56 9.98e-30 Eosinophil percentage of granulocytes; LIHC cis rs9942416 0.660 rs4704231 chr5:74986576 G/A cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs7131987 0.868 rs10771508 chr12:29414211 G/A cg12903224 chr12:29470962 FAR2 -0.37 -5.91 -0.3 8.31e-9 QT interval; LIHC trans rs62103177 0.733 rs62103232 chr18:77635553 G/A cg05926928 chr17:57297772 GDPD1 1.2 13.64 0.59 3.87e-34 Opioid sensitivity; LIHC cis rs7824557 0.707 rs3808518 chr8:11143272 A/C cg21775007 chr8:11205619 TDH -0.59 -9.74 -0.47 6.26e-20 Retinal vascular caliber; LIHC cis rs561341 1.000 rs4795667 chr17:30244443 T/C cg13647721 chr17:30228624 UTP6 0.79 7.44 0.37 8.07e-13 Hip circumference adjusted for BMI; LIHC cis rs7953249 0.564 rs11065385 chr12:121423386 A/G cg02403541 chr12:121454288 C12orf43 -0.43 -7.09 -0.36 7.56e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs10463316 0.817 rs2112419 chr5:150797804 T/C cg03212797 chr5:150827313 SLC36A1 -0.44 -6.59 -0.34 1.72e-10 Metabolite levels (Pyroglutamine); LIHC cis rs12980942 0.591 rs4591267 chr19:41765407 A/C cg25627403 chr19:41769009 HNRNPUL1 0.59 7.09 0.36 7.54e-12 Coronary artery disease; LIHC cis rs9399135 0.967 rs4451151 chr6:135310546 C/T cg24558204 chr6:135376177 HBS1L 0.4 6.58 0.34 1.77e-10 Red blood cell count; LIHC cis rs694739 0.628 rs538147 chr11:64129722 G/A cg02228329 chr11:64053129 BAD;GPR137 0.59 8.04 0.4 1.47e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC trans rs2262909 0.925 rs73019900 chr19:22286680 G/A cg17074339 chr11:11642133 GALNTL4 0.44 6.93 0.35 2.14e-11 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs11148252 0.846 rs13431 chr13:52987477 G/C cg00495681 chr13:53174319 NA 0.39 6.44 0.33 3.94e-10 Lewy body disease; LIHC cis rs4780401 0.609 rs4781141 chr16:11808769 A/C cg01061890 chr16:11836724 TXNDC11 -0.64 -10.17 -0.48 2.06e-21 Rheumatoid arthritis; LIHC cis rs7312774 0.618 rs4964500 chr12:107320788 T/C cg16260113 chr12:107380972 MTERFD3 0.85 10.95 0.51 3.91e-24 Severe influenza A (H1N1) infection; LIHC cis rs8180040 0.966 rs34634681 chr3:47579102 G/A cg16586182 chr3:47516702 SCAP 0.43 7.44 0.37 8.05e-13 Colorectal cancer; LIHC cis rs1559088 1.000 rs7260051 chr19:33550111 C/A cg27124370 chr19:33622961 WDR88 0.47 7.19 0.36 4.07e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg04352962 chr1:209979756 IRF6 0.4 6.17 0.32 1.89e-9 Cleft lip with or without cleft palate; LIHC cis rs473651 0.935 rs541013 chr2:239336492 G/A cg18131467 chr2:239335373 ASB1 1.05 19.8 0.73 1.13e-58 Multiple system atrophy; LIHC cis rs12079745 0.793 rs77538715 chr1:169290007 T/C cg09363564 chr1:169337483 NME7;BLZF1 -0.76 -6.98 -0.35 1.51e-11 QT interval; LIHC cis rs17685 0.712 rs10235086 chr7:75833138 G/T cg04592579 chr7:75616294 TMEM120A 0.4 6.79 0.34 5.07e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg16034541 chr3:195490309 MUC4 0.58 9.18 0.44 4.34e-18 Lung disease severity in cystic fibrosis; LIHC cis rs735860 0.712 rs2294864 chr6:53140928 T/A cg10236188 chr6:53219634 NA -0.41 -7.54 -0.38 4.13e-13 Glaucoma; LIHC cis rs67311347 0.866 rs1454491 chr3:40352647 C/G cg09455208 chr3:40491958 NA 0.33 6.3 0.32 8.92e-10 Renal cell carcinoma; LIHC cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg21724239 chr8:58056113 NA 0.56 7.05 0.36 1.01e-11 Developmental language disorder (linguistic errors); LIHC trans rs11039798 0.545 rs7118670 chr11:48532056 C/T cg15704280 chr7:45808275 SEPT13 0.58 6.37 0.33 6.24e-10 Axial length; LIHC cis rs1878931 0.582 rs9921152 chr16:3421199 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.68 9.0 0.44 1.63e-17 Body mass index (adult); LIHC cis rs7520050 0.966 rs1707336 chr1:46493460 T/G cg03146154 chr1:46216737 IPP -0.38 -6.19 -0.32 1.76e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1046896 0.553 rs8073413 chr17:80836005 G/A cg19500275 chr17:80737654 TBCD 0.41 5.76 0.3 1.86e-8 Glycated hemoglobin levels; LIHC cis rs8103278 1.000 rs11671524 chr19:46327166 G/A cg11657440 chr19:46296263 DMWD -0.53 -8.24 -0.41 3.78e-15 Coronary artery disease; LIHC cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 5.74 0.3 2.09e-8 Schizophrenia; LIHC cis rs79149102 0.579 rs6495146 chr15:75367630 A/T cg15902774 chr15:75289873 SCAMP5 0.4 6.0 0.31 4.97e-9 Lung cancer; LIHC cis rs4713118 0.587 rs61471148 chr6:28037032 T/A cg16479474 chr6:28041457 NA 0.48 7.14 0.36 5.5e-12 Parkinson's disease; LIHC cis rs780096 0.546 rs4425043 chr2:27733452 G/A cg27432699 chr2:27873401 GPN1 -0.6 -8.72 -0.43 1.21e-16 Total body bone mineral density; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04085039 chr16:1712707 CRAMP1L 0.44 6.63 0.34 1.27e-10 Longevity; LIHC cis rs875971 0.662 rs448725 chr7:65514628 A/G cg11764359 chr7:65958608 NA 0.85 14.27 0.61 1.37e-36 Aortic root size; LIHC trans rs6600671 0.899 rs6674392 chr1:121260662 C/G cg09829573 chr1:144692074 NBPF9 -0.4 -7.19 -0.36 4.13e-12 Hip geometry; LIHC cis rs6062302 0.545 rs2297430 chr20:62229244 T/C cg16989086 chr20:62203971 PRIC285 0.57 8.17 0.4 5.84e-15 Glioblastoma; LIHC cis rs7927592 0.913 rs2236708 chr11:68378045 G/A cg16797656 chr11:68205561 LRP5 0.49 7.71 0.38 1.39e-13 Total body bone mineral density; LIHC cis rs35110281 0.720 rs162380 chr21:44925283 T/C cg04455712 chr21:45112962 RRP1B -0.47 -7.5 -0.38 5.46e-13 Mean corpuscular volume; LIHC cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg13012494 chr21:47604986 C21orf56 -0.39 -6.08 -0.31 3.21e-9 Testicular germ cell tumor; LIHC cis rs7399018 0.643 rs6580810 chr12:51610478 C/T cg25754956 chr12:51612065 POU6F1 0.78 9.28 0.45 2.06e-18 Cisplatin-induced ototoxicity; LIHC cis rs637571 0.522 rs566590 chr11:65754062 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.93 0.43 2.71e-17 Eosinophil percentage of white cells; LIHC cis rs600806 0.888 rs10745352 chr1:109871787 T/C cg23091122 chr1:110024289 SYPL2 -0.46 -6.15 -0.32 2.14e-9 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.565 rs2836939 chr21:40578546 C/T cg11890956 chr21:40555474 PSMG1 0.96 9.64 0.46 1.34e-19 Cognitive function; LIHC cis rs700651 0.856 rs9288280 chr2:198744324 A/G cg03934865 chr2:198174659 NA 0.46 6.69 0.34 9.23e-11 Intracranial aneurysm; LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs7264396 0.709 rs2425073 chr20:34293699 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.67 -11.43 -0.53 7.81e-26 Total cholesterol levels; LIHC cis rs9660992 0.573 rs12125276 chr1:205199440 C/T cg21545522 chr1:205238299 TMCC2 0.37 7.1 0.36 7.18e-12 Mean corpuscular volume;Mean platelet volume; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg26338869 chr17:61819248 STRADA 0.61 8.91 0.43 3.16e-17 Prudent dietary pattern; LIHC cis rs1008375 0.966 rs4698636 chr4:17632834 T/C cg15017067 chr4:17643749 FAM184B 0.37 6.38 0.33 5.83e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg01238044 chr22:24384105 GSTT1 -0.44 -6.06 -0.31 3.65e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.4 0.37 1.05e-12 Prudent dietary pattern; LIHC cis rs6604026 0.643 rs1360366 chr1:93330987 A/C cg17283838 chr1:93427260 FAM69A -0.42 -5.95 -0.31 6.82e-9 Multiple sclerosis; LIHC cis rs2236918 0.710 rs2797603 chr1:242029027 T/G cg17736920 chr1:242011382 EXO1 0.42 6.3 0.32 9.07e-10 Menopause (age at onset); LIHC cis rs79387448 0.745 rs76746266 chr2:103124920 C/T cg09003973 chr2:102972529 NA 0.82 7.15 0.36 5.19e-12 Gut microbiota (bacterial taxa); LIHC cis rs72627123 0.867 rs73303129 chr14:74489244 A/T cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 6.03 0.31 4.28e-9 Morning vs. evening chronotype; LIHC cis rs490234 0.932 rs474489 chr9:128317881 C/G cg14078157 chr9:128172775 NA 0.35 5.89 0.3 9.16e-9 Mean arterial pressure; LIHC cis rs2228479 0.717 rs17233678 chr16:89809962 T/C cg19635926 chr16:89946313 TCF25 0.49 6.24 0.32 1.28e-9 Skin colour saturation; LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg20570016 chr1:156261298 TMEM79 0.38 6.11 0.31 2.75e-9 Tonsillectomy; LIHC cis rs12824058 0.767 rs4759654 chr12:130815559 A/G cg26677194 chr12:130822605 PIWIL1 0.52 7.39 0.37 1.15e-12 Menopause (age at onset); LIHC cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.14 16.31 0.66 1.19e-44 Gut microbiome composition (summer); LIHC cis rs62179067 0.708 rs11891654 chr2:179940459 G/A cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC trans rs4906332 1.000 rs2065018 chr14:103879187 C/T cg17675199 chr6:35436792 RPL10A -0.31 -6.14 -0.32 2.28e-9 Coronary artery disease; LIHC cis rs8067354 0.507 rs2645478 chr17:58014712 G/A cg02344993 chr17:57696989 CLTC 0.65 10.18 0.48 2.01e-21 Hemoglobin concentration; LIHC cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 10.0 0.48 8.11e-21 Platelet count; LIHC cis rs9814567 0.727 rs4245908 chr3:134349205 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.54 -8.7 -0.43 1.38e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1799949 0.929 rs799906 chr17:41278116 T/C cg05368731 chr17:41323189 NBR1 0.67 11.1 0.51 1.22e-24 Menopause (age at onset); LIHC cis rs7927592 0.913 rs7116994 chr11:68254627 C/T cg16797656 chr11:68205561 LRP5 0.55 8.76 0.43 8.89e-17 Total body bone mineral density; LIHC cis rs3770081 1.000 rs79152960 chr2:86290661 A/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.83 -8.49 -0.42 6.21e-16 Facial emotion recognition (sad faces); LIHC cis rs4925386 0.959 rs6121989 chr20:60916713 A/T cg24112000 chr20:60950667 NA 0.44 7.02 0.36 1.17e-11 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs17106184 1.000 rs1278516 chr1:50900021 G/A cg07174182 chr1:51127561 FAF1 -0.6 -6.67 -0.34 1.06e-10 Type 2 diabetes; LIHC cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC trans rs1005277 0.579 rs1740742 chr10:38518860 C/T cg17830980 chr10:43048298 ZNF37B -0.5 -9.54 -0.46 2.78e-19 Extrinsic epigenetic age acceleration; LIHC cis rs472402 0.560 rs10065299 chr5:6654489 T/C cg07758902 chr5:6633253 NSUN2;SRD5A1 -0.46 -5.72 -0.3 2.3e-8 Response to amphetamines; LIHC cis rs96067 0.711 rs7521145 chr1:36622903 A/G cg24686825 chr1:36642396 MAP7D1 -0.41 -7.34 -0.37 1.57e-12 Corneal structure; LIHC cis rs7208859 0.673 rs55658077 chr17:29156519 A/G cg14067834 chr17:29058358 SUZ12P 0.69 6.7 0.34 8.36e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs597539 0.654 rs655816 chr11:68626405 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.72 10.62 0.5 5.7e-23 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6504663 0.596 rs7208018 chr17:48557863 C/T cg00901687 chr17:48585270 MYCBPAP -0.43 -6.04 -0.31 4.02e-9 Visceral fat; LIHC cis rs7666738 0.830 rs6819047 chr4:98866902 G/A cg05340658 chr4:99064831 C4orf37 0.67 12.17 0.55 1.54e-28 Colonoscopy-negative controls vs population controls; LIHC cis rs9560113 1.000 rs4773387 chr13:112180955 T/C cg14154082 chr13:112174009 NA 0.3 6.26 0.32 1.16e-9 Menarche (age at onset); LIHC cis rs3617 0.625 rs7652667 chr3:52866535 C/A cg11645453 chr3:52864694 ITIH4 -0.22 -5.95 -0.31 6.65e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg06969265 chr17:73775802 H3F3B 0.47 6.0 0.31 4.92e-9 Psoriasis; LIHC trans rs877282 0.898 rs2004478 chr10:770709 C/A cg22713356 chr15:30763199 NA 1.25 11.04 0.51 2e-24 Uric acid levels; LIHC trans rs2832191 0.740 rs2012645 chr21:30445961 G/A cg14791747 chr16:20752902 THUMPD1 -0.47 -6.53 -0.33 2.42e-10 Dental caries; LIHC cis rs1707322 0.963 rs12022335 chr1:46402732 C/A cg06784218 chr1:46089804 CCDC17 0.35 6.18 0.32 1.77e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 0.545 rs73142265 chr7:65699497 G/A cg11764359 chr7:65958608 NA 0.5 6.92 0.35 2.26e-11 Aortic root size; LIHC cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg02931644 chr1:25747376 RHCE 0.33 6.91 0.35 2.36e-11 Erythrocyte sedimentation rate; LIHC cis rs8180040 0.739 rs12488225 chr3:47235107 G/A cg27129171 chr3:47204927 SETD2 0.7 12.41 0.56 1.81e-29 Colorectal cancer; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17434366 chr4:2746469 TNIP2 0.41 6.28 0.32 1e-9 Immature fraction of reticulocytes; LIHC cis rs2952156 0.883 rs2941505 chr17:37832704 A/G cg00129232 chr17:37814104 STARD3 -0.52 -9.8 -0.47 3.72e-20 Asthma; LIHC cis rs12711979 0.509 rs13035992 chr2:3826597 G/A cg17052675 chr2:3827356 NA -0.71 -15.82 -0.65 1.08e-42 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg06873352 chr17:61820015 STRADA 0.74 13.21 0.58 1.74e-32 Prudent dietary pattern; LIHC cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg13395646 chr4:1353034 KIAA1530 -0.66 -9.5 -0.46 3.65e-19 Obesity-related traits; LIHC cis rs1878931 0.559 rs1968055 chr16:3392053 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.56 7.49 0.38 5.83e-13 Body mass index (adult); LIHC cis rs2304069 0.837 rs10041451 chr5:149385197 A/C cg22760475 chr5:149380129 HMGXB3;TIGD6 0.99 12.96 0.57 1.53e-31 HIV-1 control; LIHC trans rs561341 0.739 rs4795663 chr17:30214542 T/C cg20587970 chr11:113659929 NA 0.48 6.35 0.32 6.99e-10 Hip circumference adjusted for BMI; LIHC trans rs916888 0.773 rs199445 chr17:44817408 C/T cg13957321 chr17:43675089 NA 0.5 7.97 0.4 2.39e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9858542 0.953 rs7623659 chr3:49414791 C/T cg03060546 chr3:49711283 APEH -0.46 -6.38 -0.33 5.74e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4843747 0.519 rs12599755 chr16:88107006 A/G cg00677901 chr16:88017247 BANP 0.55 8.44 0.42 9.26e-16 Menopause (age at onset); LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg23978390 chr7:1156363 C7orf50 0.54 8.36 0.41 1.63e-15 Longevity;Endometriosis; LIHC cis rs344364 0.511 rs1657144 chr16:1963989 C/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.57 -6.94 -0.35 2.02e-11 Glomerular filtration rate in chronic kidney disease; LIHC cis rs34172651 0.874 rs200534 chr16:24752641 G/A cg00152838 chr16:24741724 TNRC6A 0.45 6.04 0.31 4.13e-9 Intelligence (multi-trait analysis); LIHC cis rs7100689 0.646 rs12253992 chr10:82158710 G/A cg00277334 chr10:82204260 NA -0.47 -6.81 -0.35 4.34e-11 Post bronchodilator FEV1; LIHC trans rs9914544 1.000 rs8066385 chr17:18761133 C/T cg21372672 chr17:16614065 CCDC144A -0.28 -6.26 -0.32 1.12e-9 Educational attainment (years of education); LIHC cis rs10870270 1.000 rs6560695 chr10:133774986 C/A cg17892150 chr10:133769511 PPP2R2D -0.68 -12.79 -0.57 7.03e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs10751667 1.000 rs12798036 chr11:947585 T/C cg06064525 chr11:970664 AP2A2 -0.5 -12.56 -0.56 5.16e-30 Alzheimer's disease (late onset); LIHC cis rs712039 0.652 rs853200 chr17:35804114 G/A cg16670864 chr17:35848621 DUSP14 0.34 5.75 0.3 1.94e-8 Tuberculosis; LIHC cis rs3853824 1.000 rs3853824 chr17:54880993 T/C cg13675837 chr17:54910204 DGKE 0.39 5.88 0.3 9.79e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs73195822 0.773 rs10849903 chr12:111112319 T/C cg12870014 chr12:110450643 ANKRD13A 0.72 8.53 0.42 4.73e-16 Itch intensity from mosquito bite; LIHC cis rs826838 1.000 rs7299124 chr12:39002661 T/C cg13010199 chr12:38710504 ALG10B 0.56 6.82 0.35 4.23e-11 Heart rate; LIHC cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg00656387 chr3:40428638 ENTPD3 0.47 7.81 0.39 6.85e-14 Renal cell carcinoma; LIHC cis rs8072100 0.967 rs7219303 chr17:45737701 A/G cg08085267 chr17:45401833 C17orf57 0.39 5.85 0.3 1.16e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9311474 0.713 rs352166 chr3:52238677 C/T cg18404041 chr3:52824283 ITIH1 -0.36 -5.81 -0.3 1.44e-8 Electroencephalogram traits; LIHC cis rs2239547 0.657 rs4687672 chr3:52880543 G/A cg11645453 chr3:52864694 ITIH4 0.36 9.36 0.45 1.09e-18 Schizophrenia; LIHC cis rs5769707 0.604 rs1018814 chr22:50036900 T/C cg07959070 chr22:50026188 C22orf34 -0.34 -8.35 -0.41 1.67e-15 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.13 -0.36 5.86e-12 Diabetic kidney disease; LIHC cis rs763014 0.932 rs2384974 chr16:651279 C/G cg09256448 chr16:638327 NA 0.39 6.71 0.34 8.34e-11 Height; LIHC cis rs5769765 1.000 rs761879 chr22:50241210 G/A cg02269571 chr22:50332266 NA 0.65 8.74 0.43 1.04e-16 Schizophrenia; LIHC cis rs2845885 0.793 rs3751120 chr11:63884453 C/T cg24431193 chr11:63883947 FLRT1;MACROD1 0.7 10.43 0.49 2.68e-22 Body mass index; LIHC cis rs5770917 1.000 rs1056964 chr22:51017476 A/G cg06530441 chr22:51016950 CPT1B;CHKB-CPT1B -0.48 -5.98 -0.31 5.74e-9 Narcolepsy; LIHC cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg21171335 chr12:122356390 WDR66 0.55 7.93 0.39 3.17e-14 Mean corpuscular volume; LIHC cis rs6754311 0.731 rs309164 chr2:136691825 T/C cg07169764 chr2:136633963 MCM6 0.68 10.44 0.49 2.5e-22 Mosquito bite size; LIHC cis rs7100689 0.622 rs4536152 chr10:82119242 C/T cg01528321 chr10:82214614 TSPAN14 0.73 9.69 0.46 8.85e-20 Post bronchodilator FEV1; LIHC trans rs66573146 0.656 rs111560662 chr4:6952766 C/T cg07817883 chr1:32538562 TMEM39B 1.2 10.01 0.48 7.28e-21 Granulocyte percentage of myeloid white cells; LIHC cis rs6754311 0.638 rs1011361 chr2:136553639 G/A cg17750252 chr2:136567154 LCT 0.36 6.3 0.32 9.38e-10 Mosquito bite size; LIHC cis rs208520 0.754 rs7753158 chr6:66875633 A/C cg07460842 chr6:66804631 NA -0.73 -8.04 -0.4 1.46e-14 Exhaled nitric oxide output; LIHC cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg06238570 chr21:40685208 BRWD1 -0.54 -9.15 -0.44 5.15e-18 Cognitive function; LIHC cis rs2741335 0.876 rs2565056 chr8:27337227 G/A cg07150473 chr8:27338183 CHRNA2 -0.46 -6.57 -0.33 1.88e-10 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC cis rs55665837 0.540 rs10219313 chr11:14749849 C/T cg19336497 chr11:14380999 RRAS2 -0.34 -5.74 -0.3 2.13e-8 Vitamin D levels; LIHC cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg07092213 chr7:1199455 ZFAND2A -0.43 -6.24 -0.32 1.28e-9 Longevity;Endometriosis; LIHC cis rs16854884 0.657 rs1979910 chr3:143710268 A/C cg06585982 chr3:143692056 C3orf58 0.64 8.95 0.44 2.31e-17 Economic and political preferences (feminism/equality); LIHC cis rs7662987 0.517 rs2851265 chr4:100029684 A/G cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs1568889 1.000 rs66702115 chr11:28181703 T/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.52 7.27 0.37 2.41e-12 Bipolar disorder; LIHC cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg27572855 chr1:25598939 RHD 0.4 8.7 0.43 1.42e-16 Erythrocyte sedimentation rate; LIHC cis rs9918079 0.542 rs7688984 chr4:15657253 G/T cg21123203 chr4:15471301 CC2D2A -0.4 -5.84 -0.3 1.23e-8 Obesity-related traits; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg11635524 chr19:46850777 PPP5C 0.55 6.28 0.32 1.04e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs35306767 0.903 rs35957139 chr10:884889 C/T cg26597838 chr10:835615 NA 1.49 17.34 0.68 8.86e-49 Eosinophil percentage of granulocytes; LIHC cis rs12549902 1.000 rs12550613 chr8:41510260 G/C cg17182837 chr8:41585554 ANK1 -0.23 -5.74 -0.3 2.07e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs6088590 0.687 rs6088582 chr20:33286798 G/A cg06115741 chr20:33292138 TP53INP2 0.42 6.13 0.31 2.45e-9 Coronary artery disease; LIHC cis rs751728 1.000 rs6925273 chr6:33732448 A/G cg25922239 chr6:33757077 LEMD2 0.48 7.79 0.39 8.21e-14 Crohn's disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14787155 chr3:108308533 DZIP3;KIAA1524 0.44 6.28 0.32 1.04e-9 Lung function (FEV1/FVC); LIHC cis rs62179067 0.655 rs11890988 chr2:179944932 G/A cg07532576 chr2:179544947 TTN 0.67 6.03 0.31 4.19e-9 Late-onset Alzheimer's disease; LIHC cis rs2637266 0.905 rs11001834 chr10:78360494 T/C cg18941641 chr10:78392320 NA 0.28 5.87 0.3 1.05e-8 Pulmonary function; LIHC cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg06420487 chr17:61919686 SMARCD2 0.45 6.22 0.32 1.43e-9 Height; LIHC trans rs6866721 0.791 rs7449327 chr5:116216248 A/G cg07571379 chr11:134631427 NA -0.28 -6.07 -0.31 3.4e-9 Body mass index; LIHC cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg11764359 chr7:65958608 NA 0.69 9.4 0.45 8.19e-19 Aortic root size; LIHC cis rs7044106 0.791 rs4836830 chr9:123483668 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.73 11.79 0.54 3.88e-27 Hip circumference adjusted for BMI; LIHC cis rs72627509 0.951 rs72606404 chr4:57841213 G/C cg16868167 chr4:57843880 C4orf14;POLR2B -0.62 -8.98 -0.44 1.83e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs2727020 0.521 rs2088526 chr11:49531968 G/A cg03929089 chr4:120376271 NA 0.7 10.22 0.48 1.4e-21 Coronary artery disease; LIHC cis rs1538970 0.962 rs3219472 chr1:45804050 A/G cg05343316 chr1:45956843 TESK2 -0.62 -8.89 -0.43 3.67e-17 Platelet count; LIHC cis rs921968 0.643 rs579610 chr2:219327582 C/A cg17980119 chr2:219472607 PLCD4 0.35 6.18 0.32 1.84e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs6545883 0.931 rs11125885 chr2:61755728 G/C cg14146966 chr2:61757674 XPO1 0.47 8.21 0.41 4.61e-15 Tuberculosis; LIHC cis rs9649465 0.688 rs34967330 chr7:123318560 A/C cg03229431 chr7:123269106 ASB15 -0.39 -8.27 -0.41 3.09e-15 Migraine; LIHC cis rs7106204 0.748 rs7122986 chr11:24224634 G/A ch.11.24196551F chr11:24239977 NA 0.8 11.25 0.52 3.54e-25 Response to Homoharringtonine (cytotoxicity); LIHC cis rs17106184 1.000 rs72900983 chr1:51192756 T/C cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs4925386 1.000 rs4925382 chr20:60918542 G/C cg03945807 chr20:60948434 NA -0.36 -6.53 -0.33 2.43e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2380220 0.808 rs2386669 chr6:95902121 C/T cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs765787 0.530 rs11636404 chr15:45535861 C/G cg24006582 chr15:45444508 DUOX1 -0.53 -7.7 -0.38 1.5e-13 Uric acid levels; LIHC cis rs10911232 0.524 rs10911229 chr1:183050368 C/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.64 0.5 4.8e-23 Hypertriglyceridemia; LIHC cis rs17152411 0.652 rs4962712 chr10:126647052 A/C cg07906193 chr10:126599966 NA -0.29 -5.86 -0.3 1.08e-8 Height; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg11494091 chr17:61959527 GH2 0.44 8.07 0.4 1.17e-14 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs778691 chr7:65873092 G/C cg05590025 chr7:65112418 INTS4L2 -0.55 -5.97 -0.31 5.78e-9 Diabetic kidney disease; LIHC cis rs6540556 0.723 rs6679099 chr1:209895852 T/G cg05527609 chr1:210001259 C1orf107 -0.56 -7.61 -0.38 2.74e-13 Red blood cell count; LIHC cis rs6456156 0.586 rs13195158 chr6:167481392 G/A cg07741184 chr6:167504864 NA 0.27 6.25 0.32 1.19e-9 Primary biliary cholangitis; LIHC cis rs2242116 0.796 rs9852082 chr3:46972377 T/C cg02527881 chr3:46936655 PTH1R -0.45 -9.22 -0.45 3.2e-18 Birth weight; LIHC cis rs611744 0.647 rs10106246 chr8:109268710 T/C cg21045802 chr8:109455806 TTC35 0.58 10.31 0.49 6.89e-22 Dupuytren's disease; LIHC cis rs2257205 0.667 rs16943147 chr17:56720752 C/A cg05425664 chr17:57184151 TRIM37 -0.59 -6.54 -0.33 2.23e-10 Pancreatic cancer; LIHC cis rs6952808 0.792 rs4721184 chr7:1950784 T/C cg02951883 chr7:2050386 MAD1L1 -0.61 -9.25 -0.45 2.48e-18 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg26338869 chr17:61819248 STRADA 0.58 8.53 0.42 4.73e-16 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs2243480 chr7:65599196 C/T cg07424592 chr7:64974309 NA 0.78 8.67 0.42 1.75e-16 Diabetic kidney disease; LIHC cis rs559928 0.606 rs12419038 chr11:63912736 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.7 7.21 0.36 3.62e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs9911578 0.967 rs2333410 chr17:57137129 G/A cg05425664 chr17:57184151 TRIM37 0.59 8.96 0.44 2.14e-17 Intelligence (multi-trait analysis); LIHC cis rs9325144 0.581 rs2653758 chr12:38946233 G/T cg26384229 chr12:38710491 ALG10B -0.41 -6.46 -0.33 3.66e-10 Morning vs. evening chronotype; LIHC cis rs735860 0.737 rs2397139 chr6:53150804 C/G cg10236188 chr6:53219634 NA -0.4 -7.28 -0.37 2.36e-12 Glaucoma; LIHC cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.54 -0.59 9.53e-34 Vitiligo; LIHC cis rs3806843 0.676 rs753280 chr5:140024042 C/T cg19875535 chr5:140030758 IK 0.36 5.97 0.31 5.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs74233809 1.000 rs79237883 chr10:104940946 T/C cg03493300 chr10:104813866 CNNM2 0.45 5.91 0.3 8.41e-9 Birth weight; LIHC cis rs1568889 1.000 rs7949704 chr11:28373543 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.47 6.21 0.32 1.56e-9 Bipolar disorder; LIHC cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg27572855 chr1:25598939 RHD 0.4 8.6 0.42 2.88e-16 Erythrocyte sedimentation rate; LIHC cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg20887711 chr4:1340912 KIAA1530 0.5 7.82 0.39 6.7e-14 Obesity-related traits; LIHC cis rs6088590 0.561 rs3891369 chr20:33161127 C/T cg08999081 chr20:33150536 PIGU 0.69 13.74 0.6 1.57e-34 Coronary artery disease; LIHC cis rs10876993 0.890 rs774887 chr12:58034835 A/G cg15848620 chr12:58087721 OS9 -0.53 -7.21 -0.36 3.54e-12 Celiac disease or Rheumatoid arthritis; LIHC cis rs11030122 0.673 rs10835596 chr11:4099666 C/T cg18678763 chr11:4115507 RRM1 -0.58 -8.57 -0.42 3.72e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs1023500 0.505 rs134874 chr22:42661144 A/G cg00645731 chr22:42541494 CYP2D7P1 0.33 5.96 0.31 6.39e-9 Schizophrenia; LIHC cis rs10876993 0.893 rs3825078 chr12:58089413 A/T cg18357645 chr12:58087776 OS9 0.53 8.57 0.42 3.5e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg26338869 chr17:61819248 STRADA 0.54 7.19 0.36 4.19e-12 Height; LIHC cis rs96067 0.711 rs11263861 chr1:36628033 G/A cg24686825 chr1:36642396 MAP7D1 -0.42 -7.65 -0.38 2.1e-13 Corneal structure; LIHC cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg05564831 chr3:52568323 NT5DC2 0.37 5.98 0.31 5.66e-9 Bipolar disorder; LIHC cis rs1816752 0.837 rs7139748 chr13:24985669 G/A cg22771759 chr13:24902376 NA 0.31 6.35 0.32 6.94e-10 Obesity-related traits; LIHC cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.862 rs35034167 chr7:65580166 C/G cg11764359 chr7:65958608 NA -0.82 -13.6 -0.59 5.83e-34 Aortic root size; LIHC cis rs919433 0.963 rs1429417 chr2:198158171 T/G cg03934865 chr2:198174659 NA -0.59 -9.48 -0.46 4.52e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs8072100 1.000 rs8065669 chr17:45724996 G/A cg08085267 chr17:45401833 C17orf57 -0.57 -8.54 -0.42 4.49e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg05484376 chr2:27715224 FNDC4 0.37 6.31 0.32 8.8e-10 Total body bone mineral density; LIHC cis rs9790314 0.818 rs6797066 chr3:161008725 T/A cg03342759 chr3:160939853 NMD3 -0.8 -13.17 -0.58 2.51e-32 Morning vs. evening chronotype; LIHC cis rs4975616 0.869 rs455433 chr5:1336243 A/G cg06550200 chr5:1325588 CLPTM1L -0.68 -10.8 -0.5 1.33e-23 Lung cancer; LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg24503407 chr1:205819492 PM20D1 0.77 10.58 0.5 8.14e-23 Menarche (age at onset); LIHC cis rs9902453 0.934 rs4427857 chr17:28457989 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 10.01 0.48 7.14e-21 Coffee consumption (cups per day); LIHC cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg11062466 chr8:58055876 NA 0.47 6.37 0.33 5.94e-10 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03160445 chr3:100120349 LNP1;TOMM70A 0.39 6.04 0.31 3.96e-9 Pancreatic cancer; LIHC cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs3106136 0.649 rs11097419 chr4:95298601 A/G cg11021082 chr4:95130006 SMARCAD1 0.36 6.13 0.31 2.4e-9 Capecitabine sensitivity; LIHC cis rs11255291 0.668 rs719748 chr10:7731885 A/G cg00997801 chr10:7671259 ITIH5 0.36 5.82 0.3 1.34e-8 Ovarian reserve; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17456994 chr10:6130864 RBM17 0.54 7.19 0.36 4.16e-12 Lung function (FEV1/FVC); LIHC cis rs9527 0.568 rs12772775 chr10:104702999 C/A cg15744005 chr10:104629667 AS3MT -0.29 -5.73 -0.3 2.16e-8 Arsenic metabolism; LIHC cis rs735396 0.595 rs1169279 chr12:121455873 C/T cg15155738 chr12:121454335 C12orf43 0.54 7.85 0.39 5.42e-14 N-glycan levels; LIHC trans rs4650994 1.000 rs10913570 chr1:178523126 A/C cg05059571 chr16:84539110 KIAA1609 -0.38 -6.33 -0.32 7.74e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs2180341 1.000 rs2057223 chr6:127637374 T/C cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs10197940 0.624 rs3771901 chr2:152432481 G/A cg06191203 chr2:152266755 RIF1 -0.44 -7.58 -0.38 3.38e-13 Lung cancer; LIHC cis rs9322817 0.691 rs4504502 chr6:105325332 A/G cg02098413 chr6:105308735 HACE1 0.41 7.7 0.38 1.49e-13 Thyroid stimulating hormone; LIHC trans rs6489882 0.902 rs1156361 chr12:113375983 T/C cg10175203 chr3:128143634 NA 0.38 6.17 0.32 1.96e-9 Chronic lymphocytic leukemia; LIHC trans rs116095464 0.510 rs7714944 chr5:231765 C/T cg00938859 chr5:1591904 SDHAP3 0.54 6.57 0.33 1.87e-10 Breast cancer; LIHC cis rs4819852 0.958 rs2238784 chr22:19972559 G/A cg07821417 chr22:19972146 ARVCF 0.46 6.61 0.34 1.48e-10 Pulse pressure; LIHC cis rs7829975 0.659 rs4382480 chr8:8721473 C/T cg06636001 chr8:8085503 FLJ10661 0.43 7.03 0.36 1.12e-11 Mood instability; LIHC cis rs9583531 0.600 rs1441042 chr13:111365589 T/G cg24331049 chr13:111365604 ING1 0.8 13.67 0.59 3.07e-34 Coronary artery disease; LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg26338869 chr17:61819248 STRADA 0.53 7.21 0.36 3.73e-12 Height; LIHC cis rs6952808 0.531 rs1107351 chr7:2177093 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.77 -0.47 4.82e-20 Bipolar disorder and schizophrenia; LIHC cis rs4474465 0.920 rs7944485 chr11:78225261 T/C cg02023728 chr11:77925099 USP35 -0.36 -6.23 -0.32 1.39e-9 Alzheimer's disease (survival time); LIHC cis rs1997103 1.000 rs2177802 chr7:55410789 G/A cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC trans rs1814175 0.817 rs10839465 chr11:49981554 C/A cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.45 8.27 0.41 3.07e-15 Total body bone mineral density; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20476319 chr12:104457893 HCFC2 -0.52 -6.12 -0.31 2.62e-9 Systolic blood pressure; LIHC cis rs7552404 1.000 rs12123977 chr1:76209754 A/G cg03433033 chr1:76189801 ACADM -0.56 -7.38 -0.37 1.19e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9611519 0.964 rs20551 chr22:41548008 A/G cg03806693 chr22:41940476 POLR3H -0.68 -7.31 -0.37 1.88e-12 Neuroticism; LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg04013166 chr16:89971882 TCF25 0.62 8.83 0.43 5.68e-17 Interleukin-17 levels; LIHC cis rs1570884 0.516 rs7330830 chr13:50167929 T/A cg08779649 chr13:50194554 NA 0.36 6.55 0.33 2.14e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg03517284 chr6:25882590 NA 0.62 7.76 0.39 9.92e-14 Intelligence (multi-trait analysis); LIHC cis rs911555 0.570 rs11625397 chr14:104027557 A/G cg24130564 chr14:104152367 KLC1 0.62 11.22 0.52 4.39e-25 Intelligence (multi-trait analysis); LIHC cis rs263063 0.749 rs11085111 chr19:5069261 C/T cg18473234 chr19:5097819 KDM4B 0.56 6.83 0.35 3.83e-11 Periodontitis (CDC/AAP); LIHC cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.08 0.31 3.13e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs17685 0.712 rs28506984 chr7:75763484 A/G cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6754311 0.551 rs2304599 chr2:136528004 C/G cg07169764 chr2:136633963 MCM6 -0.78 -11.92 -0.54 1.27e-27 Mosquito bite size; LIHC cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg02290350 chr8:58132656 NA 0.44 8.64 0.42 2.13e-16 Developmental language disorder (linguistic errors); LIHC cis rs6430585 0.528 rs309162 chr2:136690783 T/A cg25344623 chr2:136566232 LCT -0.37 -6.06 -0.31 3.5e-9 Corneal structure; LIHC cis rs8180040 0.620 rs749511 chr3:47035735 A/C cg27129171 chr3:47204927 SETD2 -0.54 -8.88 -0.43 3.74e-17 Colorectal cancer; LIHC cis rs9473924 0.542 rs2857501 chr6:50797286 A/G cg14470998 chr6:50812995 TFAP2B 0.98 11.01 0.51 2.45e-24 Body mass index; LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg09177884 chr7:1199841 ZFAND2A -0.42 -6.01 -0.31 4.67e-9 Longevity;Endometriosis; LIHC cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg18252515 chr7:66147081 NA -1.3 -16.87 -0.67 7.14e-47 Diabetic kidney disease; LIHC cis rs79387448 0.638 rs78123896 chr2:103075417 T/C cg09003973 chr2:102972529 NA 1.09 9.57 0.46 2.29e-19 Gut microbiota (bacterial taxa); LIHC cis rs763121 0.925 rs1043312 chr22:39131727 T/G cg06544989 chr22:39130855 UNC84B 0.36 5.98 0.31 5.73e-9 Menopause (age at onset); LIHC cis rs9921222 0.500 rs8046256 chr16:393948 C/T cg08923669 chr16:420230 MRPL28 -0.61 -8.07 -0.4 1.23e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs78545713 0.649 rs79759076 chr6:26223694 C/G cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs924607 1.000 rs1697978 chr5:642829 A/G cg04476341 chr5:669733 TPPP 0.38 8.77 0.43 8.62e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs6977660 0.714 rs2390156 chr7:19786138 A/T cg07541023 chr7:19748670 TWISTNB 0.48 7.03 0.36 1.13e-11 Thyroid stimulating hormone; LIHC cis rs4660306 0.672 rs534534 chr1:46024701 G/A cg03123370 chr1:45965343 CCDC163P;MMACHC -0.51 -5.97 -0.31 5.79e-9 Homocysteine levels; LIHC cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg03517284 chr6:25882590 NA -0.64 -8.97 -0.44 1.95e-17 Blood metabolite levels; LIHC cis rs10838687 1.000 rs4752979 chr11:47339180 A/G cg26139080 chr11:47293733 MADD -0.44 -6.34 -0.32 7.29e-10 Proinsulin levels; LIHC cis rs763121 0.819 rs5757161 chr22:38990662 G/A cg06022373 chr22:39101656 GTPBP1 0.72 14.4 0.61 4.38e-37 Menopause (age at onset); LIHC cis rs4891159 0.824 rs17059362 chr18:74144307 G/A cg24786174 chr18:74118243 ZNF516 -0.74 -13.35 -0.59 5e-33 Longevity; LIHC cis rs2075371 0.933 rs1833475 chr7:133958263 C/T cg20476274 chr7:133979776 SLC35B4 0.75 12.92 0.57 2.25e-31 Mean platelet volume; LIHC cis rs3736485 0.966 rs8042840 chr15:51908498 C/T cg08986416 chr15:51914746 DMXL2 -0.47 -6.98 -0.35 1.59e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6879260 0.714 rs888926 chr5:179738101 A/G cg23221052 chr5:179740743 GFPT2 -0.49 -7.03 -0.36 1.15e-11 Height; LIHC cis rs2072499 0.898 rs2736609 chr1:156202640 C/T cg25208724 chr1:156163844 SLC25A44 0.56 9.4 0.45 7.99e-19 Testicular germ cell tumor; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg14397775 chr11:65729156 SART1 -0.46 -6.25 -0.32 1.23e-9 Alopecia areata; LIHC cis rs35306767 0.855 rs12770190 chr10:951262 C/T cg20503657 chr10:835505 NA 0.99 11.01 0.51 2.42e-24 Eosinophil percentage of granulocytes; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg05590025 chr7:65112418 INTS4L2 0.44 6.63 0.34 1.32e-10 Calcium levels; LIHC cis rs9309473 0.583 rs11126397 chr2:73588733 C/T cg20560298 chr2:73613845 ALMS1 -0.46 -7.28 -0.37 2.26e-12 Metabolite levels; LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg11905131 chr22:24372483 LOC391322 -0.72 -11.21 -0.52 4.86e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4891159 0.513 rs35534021 chr18:74130523 G/A cg24786174 chr18:74118243 ZNF516 0.81 16.11 0.66 7.42e-44 Longevity; LIHC cis rs11690935 0.885 rs6752812 chr2:172851502 C/A cg13550731 chr2:172543902 DYNC1I2 -0.8 -14.18 -0.61 3.3e-36 Schizophrenia; LIHC cis rs2070433 0.539 rs2070432 chr21:47957332 G/A cg12379764 chr21:47803548 PCNT 0.64 9.91 0.47 1.6e-20 Lymphocyte counts; LIHC cis rs12908161 1.000 rs12908161 chr15:85207825 A/G cg17507749 chr15:85114479 UBE2QP1 0.68 7.61 0.38 2.72e-13 Schizophrenia; LIHC cis rs3020736 0.500 rs6002605 chr22:42494335 A/G cg04733989 chr22:42467013 NAGA -0.67 -9.64 -0.46 1.33e-19 Autism spectrum disorder or schizophrenia; LIHC cis rs12477438 0.501 rs11692336 chr2:99740606 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs2573652 1.000 rs2581346 chr15:100514178 T/G cg09918751 chr15:100517450 ADAMTS17 -0.81 -14.74 -0.62 2.09e-38 Height; LIHC cis rs16858210 0.542 rs12636826 chr3:183558581 G/C cg25686905 chr3:183603175 PARL -0.47 -8.24 -0.41 3.72e-15 Menopause (age at onset); LIHC cis rs6500602 0.702 rs2270366 chr16:4558615 A/G cg08645402 chr16:4508243 NA -0.43 -8.32 -0.41 2.19e-15 Schizophrenia; LIHC cis rs1008375 0.932 rs6449317 chr4:17631253 T/C cg16339924 chr4:17578868 LAP3 0.53 6.89 0.35 2.61e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs60871478 1.000 rs62432250 chr7:801792 C/G cg04727924 chr7:799746 HEATR2 -0.58 -8.53 -0.42 4.77e-16 Cerebrospinal P-tau181p levels; LIHC cis rs35306767 0.951 rs61833265 chr10:990143 C/T cg26597838 chr10:835615 NA 1.07 10.51 0.49 1.4e-22 Eosinophil percentage of granulocytes; LIHC cis rs7927771 0.524 rs7129797 chr11:47667167 G/C cg20307385 chr11:47447363 PSMC3 0.77 11.64 0.53 1.34e-26 Subjective well-being; LIHC trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg13957321 chr17:43675089 NA 0.5 7.88 0.39 4.51e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg21782813 chr7:2030301 MAD1L1 -0.54 -10.0 -0.48 8.02e-21 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs9328478 chr6:8519183 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.79 0.54 3.68e-27 Motion sickness; LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg21003380 chr1:156261207 TMEM79 0.38 6.07 0.31 3.49e-9 Tonsillectomy; LIHC cis rs2439831 0.850 rs12442297 chr15:44168470 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.55 7.08 0.36 8.31e-12 Lung cancer in ever smokers; LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg00800038 chr16:89945340 TCF25 -0.66 -10.35 -0.49 5.25e-22 Skin colour saturation; LIHC cis rs911119 1.000 rs6048956 chr20:23609301 C/T cg16589663 chr20:23618590 CST3 0.74 7.52 0.38 4.79e-13 Chronic kidney disease; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg25506325 chr7:2093962 MAD1L1 0.59 6.25 0.32 1.22e-9 Mean platelet volume; LIHC cis rs7078219 0.524 rs6584277 chr10:101278055 A/G cg06854084 chr10:101292507 NKX2-3 -0.35 -6.39 -0.33 5.28e-10 Dental caries; LIHC trans rs6489882 0.836 rs10850100 chr12:113364512 T/C cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6.02e-10 Chronic lymphocytic leukemia; LIHC trans rs1814175 0.645 rs847632 chr11:49926097 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.82 0.35 4.17e-11 Height; LIHC cis rs4474465 0.915 rs10128737 chr11:78186687 G/A cg27205649 chr11:78285834 NARS2 -0.38 -5.78 -0.3 1.68e-8 Alzheimer's disease (survival time); LIHC cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg25364880 chr3:44379878 C3orf23 0.41 5.89 0.3 9.23e-9 Depressive symptoms; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.25 -0.32 1.25e-9 Total body bone mineral density; LIHC cis rs7044106 0.791 rs4836829 chr9:123482747 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.72 11.47 0.53 5.47e-26 Hip circumference adjusted for BMI; LIHC cis rs7474896 0.559 rs1208645 chr10:38132087 C/T cg25427524 chr10:38739819 LOC399744 0.47 5.98 0.31 5.67e-9 Obesity (extreme); LIHC cis rs6459804 1.000 rs73163880 chr7:157508755 C/T cg05731713 chr7:157510257 PTPRN2 0.24 6.53 0.33 2.43e-10 Bipolar disorder and schizophrenia; LIHC cis rs2576037 0.583 rs12386118 chr18:44540376 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.73 11.58 0.53 2.11e-26 Personality dimensions; LIHC cis rs7224737 1.000 rs1869365 chr17:40293865 T/C cg20291162 chr17:40259547 DHX58 -0.41 -6.65 -0.34 1.16e-10 Fibrinogen levels; LIHC cis rs6500602 0.701 rs4785968 chr16:4535307 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.51 8.1 0.4 9.96e-15 Schizophrenia; LIHC cis rs910316 0.967 rs35446981 chr14:75637351 A/T cg08847533 chr14:75593920 NEK9 -0.86 -17.71 -0.69 3.01e-50 Height; LIHC cis rs2439831 1.000 rs689754 chr15:43775895 A/G cg15269541 chr15:43626905 ADAL -0.3 -5.81 -0.3 1.45e-8 Lung cancer in ever smokers; LIHC cis rs6088590 0.687 rs13044899 chr20:33287078 G/A cg08999081 chr20:33150536 PIGU 0.59 10.7 0.5 3.1e-23 Coronary artery disease; LIHC cis rs12048904 0.930 rs11166529 chr1:101333733 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 8.07 0.4 1.21e-14 Multiple sclerosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12977448 chr10:14920832 SUV39H2 0.47 6.7 0.34 8.69e-11 Pancreatic cancer; LIHC cis rs2836950 0.545 rs2836956 chr21:40623018 C/G cg06238570 chr21:40685208 BRWD1 0.46 7.45 0.37 7.85e-13 Menarche (age at onset); LIHC trans rs62458065 0.513 rs702831 chr7:32579715 C/T cg00845942 chr12:64062724 DPY19L2 -0.56 -6.03 -0.31 4.17e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs11190604 1.000 rs10509744 chr10:102271579 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.14 0.4 7.57e-15 Palmitoleic acid (16:1n-7) levels; LIHC trans rs2742417 0.603 rs2742448 chr3:45764246 C/T cg11996395 chr10:103912126 NOLC1 0.45 6.67 0.34 1e-10 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs4474465 1.000 rs7943815 chr11:78173160 A/G cg27205649 chr11:78285834 NARS2 -0.38 -5.97 -0.31 5.79e-9 Alzheimer's disease (survival time); LIHC cis rs7447593 0.666 rs10866705 chr5:176801131 G/T cg06060754 chr5:176797920 RGS14 -0.52 -9.89 -0.47 1.84e-20 Urinary electrolytes (magnesium/calcium ratio); LIHC cis rs6840360 0.571 rs1822347 chr4:152525319 A/G cg22705602 chr4:152727874 NA -0.32 -6.24 -0.32 1.31e-9 Intelligence (multi-trait analysis); LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.96 -0.31 6.27e-9 Menopause (age at onset); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07685765 chr19:48964041 KCNJ14 -0.36 -6.06 -0.31 3.54e-9 Lung function (FEV1/FVC); LIHC cis rs2404602 0.716 rs67888330 chr15:76752483 A/G cg23625390 chr15:77176239 SCAPER 0.37 6.13 0.31 2.37e-9 Blood metabolite levels; LIHC trans rs10838798 0.504 rs11039632 chr11:48297280 C/T cg15704280 chr7:45808275 SEPT13 -0.42 -6.37 -0.33 6.26e-10 Height; LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg05484376 chr2:27715224 FNDC4 0.38 6.51 0.33 2.71e-10 Total body bone mineral density; LIHC cis rs10744422 1.000 rs897386 chr12:123341289 A/C cg25930673 chr12:123319894 HIP1R -0.89 -11.66 -0.53 1.08e-26 Schizophrenia; LIHC cis rs6754311 0.731 rs748841 chr2:136558157 C/T cg07305463 chr2:136567211 LCT 0.39 7.55 0.38 3.88e-13 Mosquito bite size; LIHC cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg21782813 chr7:2030301 MAD1L1 0.4 6.69 0.34 8.97e-11 Bipolar disorder and schizophrenia; LIHC cis rs9309711 0.736 rs13412581 chr2:3497187 G/A cg10845886 chr2:3471009 TTC15 -0.5 -8.76 -0.43 9.01e-17 Neurofibrillary tangles; LIHC cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.59 0.34 1.66e-10 Bipolar disorder; LIHC cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg08888203 chr3:10149979 C3orf24 0.59 6.55 0.33 2.08e-10 Alzheimer's disease; LIHC cis rs34172651 0.917 rs8049667 chr16:24773524 G/A cg00152838 chr16:24741724 TNRC6A -0.49 -6.51 -0.33 2.7e-10 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg25072359 chr17:41440525 NA 0.39 6.07 0.31 3.42e-9 Menopause (age at onset); LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs12478296 0.901 rs6731775 chr2:242999443 T/C cg06360820 chr2:242988706 NA -0.8 -11.91 -0.54 1.4e-27 Obesity-related traits; LIHC trans rs3780486 0.846 rs6476399 chr9:33123013 A/G cg20290983 chr6:43655470 MRPS18A 1.15 29.33 0.85 2.15e-95 IgG glycosylation; LIHC trans rs7615952 0.673 rs9289270 chr3:125636979 A/T cg07211511 chr3:129823064 LOC729375 -0.82 -8.44 -0.42 9.26e-16 Blood pressure (smoking interaction); LIHC cis rs7927592 0.956 rs11228277 chr11:68308324 G/A cg01657329 chr11:68192670 LRP5 -0.47 -6.24 -0.32 1.31e-9 Total body bone mineral density; LIHC cis rs523522 0.892 rs4767916 chr12:121024032 T/C cg12219531 chr12:120966889 COQ5 0.68 13.18 0.58 2.41e-32 High light scatter reticulocyte count; LIHC cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs7412746 0.658 rs12090215 chr1:150893660 C/A cg17724175 chr1:150552817 MCL1 0.43 8.46 0.42 7.82e-16 Melanoma; LIHC cis rs5769765 0.955 rs6520066 chr22:50294988 C/T cg02269571 chr22:50332266 NA -0.61 -8.74 -0.43 1.03e-16 Schizophrenia; LIHC cis rs6752107 0.936 rs10187822 chr2:234206474 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.51 7.45 0.37 7.77e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs896854 0.517 rs896851 chr8:95950251 T/C cg23172400 chr8:95962367 TP53INP1 -0.33 -6.61 -0.34 1.43e-10 Type 2 diabetes; LIHC cis rs425277 1.000 rs74877653 chr1:2065949 C/T cg24578937 chr1:2090814 PRKCZ 0.49 8.47 0.42 7.22e-16 Height; LIHC trans rs17685 0.753 rs1637051 chr7:75730659 G/A cg19862616 chr7:65841803 NCRNA00174 0.92 18.56 0.71 1.05e-53 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7312933 0.933 rs4534650 chr12:42444222 A/G cg01256987 chr12:42539512 GXYLT1 -0.4 -6.62 -0.34 1.42e-10 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2033711 0.622 rs975947 chr19:58898193 C/T cg13877915 chr19:58951672 ZNF132 0.43 6.4 0.33 5.18e-10 Uric acid clearance; LIHC cis rs9303401 0.659 rs12602808 chr17:56698420 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 3.17e-33 Cognitive test performance; LIHC cis rs4742903 1.000 rs4742903 chr9:106856793 G/C cg14250997 chr9:106856677 SMC2 0.42 7.23 0.36 3.22e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1707322 1.000 rs11211248 chr1:46476844 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.45 0.33 3.8e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs10504229 0.871 rs10504226 chr8:58159283 A/G cg21724239 chr8:58056113 NA 0.44 5.87 0.3 1.03e-8 Developmental language disorder (linguistic errors); LIHC cis rs2439831 1.000 rs2264239 chr15:43765533 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.8 13.91 0.6 3.46e-35 Lung cancer in ever smokers; LIHC cis rs7937682 0.889 rs12360825 chr11:111528786 A/T cg09085632 chr11:111637200 PPP2R1B -1.02 -12.9 -0.57 2.79e-31 Primary sclerosing cholangitis; LIHC cis rs1059312 0.808 rs2170989 chr12:129291317 T/C cg09035930 chr12:129282057 SLC15A4 -0.59 -11.19 -0.52 5.4e-25 Systemic lupus erythematosus; LIHC cis rs1801251 1.000 rs6724117 chr2:233593660 T/G cg08000102 chr2:233561755 GIGYF2 0.76 11.52 0.53 3.64e-26 Coronary artery disease; LIHC cis rs9640161 0.830 rs3757423 chr7:150067714 A/G cg12556325 chr7:150026731 C7orf29;LRRC61 0.45 7.97 0.4 2.42e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7116495 0.881 rs6592449 chr11:71670222 C/T cg26138937 chr11:71823887 C11orf51 -0.82 -8.17 -0.4 6.02e-15 Severe influenza A (H1N1) infection; LIHC cis rs7903847 0.642 rs7078004 chr10:99140511 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg22150397 chr12:82752718 CCDC59;C12orf26 0.42 6.58 0.34 1.73e-10 Calcium levels; LIHC cis rs7772486 0.875 rs9322044 chr6:146369608 T/C cg05347473 chr6:146136440 FBXO30 0.38 6.22 0.32 1.47e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.673 rs3818908 chr10:99132701 A/G cg08345082 chr10:99160200 RRP12 -0.36 -6.09 -0.31 3.03e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg00656387 chr3:40428638 ENTPD3 -0.51 -8.6 -0.42 2.86e-16 Renal cell carcinoma; LIHC cis rs7129220 0.588 rs16907462 chr11:10137404 T/C cg01453529 chr11:10209919 SBF2 -0.37 -6.68 -0.34 9.75e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs1949733 0.675 rs2010758 chr4:8475623 G/A cg11789530 chr4:8429930 ACOX3 0.71 10.14 0.48 2.71e-21 Response to antineoplastic agents; LIHC cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg03264133 chr6:25882463 NA -0.63 -8.85 -0.43 4.88e-17 Blood metabolite levels; LIHC cis rs769267 0.930 rs3752151 chr19:19616026 T/C cg03709012 chr19:19516395 GATAD2A 1.01 17.87 0.69 6.76e-51 Tonsillectomy; LIHC cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg06481639 chr22:41940642 POLR3H 0.7 7.28 0.37 2.38e-12 Vitiligo; LIHC cis rs7086627 0.515 rs7907969 chr10:82153005 T/A cg01528321 chr10:82214614 TSPAN14 0.43 6.49 0.33 3.08e-10 Post bronchodilator FEV1; LIHC cis rs9611565 0.649 rs738422 chr22:42123399 C/T cg03806693 chr22:41940476 POLR3H 0.8 8.97 0.44 2e-17 Vitiligo; LIHC cis rs950776 0.518 rs4886572 chr15:78837452 A/G cg06917634 chr15:78832804 PSMA4 -0.88 -13.34 -0.58 5.71e-33 Sudden cardiac arrest; LIHC cis rs12142240 0.698 rs28578741 chr1:46825176 T/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs2479724 0.846 rs2488338 chr6:41808351 A/G cg17623882 chr6:41773611 USP49 -0.56 -8.91 -0.43 3.03e-17 Menarche (age at onset); LIHC cis rs4474465 0.920 rs7396701 chr11:78202699 A/C cg27205649 chr11:78285834 NARS2 0.39 6.09 0.31 2.97e-9 Alzheimer's disease (survival time); LIHC cis rs77637988 0.577 rs6705802 chr2:48603483 A/C cg15846641 chr2:48541264 FOXN2 0.57 7.67 0.38 1.76e-13 Joint mobility (Beighton score); LIHC trans rs11098499 0.575 rs9996586 chr4:120326942 A/G cg25214090 chr10:38739885 LOC399744 0.42 6.93 0.35 2.15e-11 Corneal astigmatism; LIHC cis rs600231 0.706 rs11227221 chr11:65319265 T/C cg10628098 chr11:65292300 SCYL1 -0.38 -5.91 -0.3 8.31e-9 Bone mineral density; LIHC trans rs941408 1.000 rs1640272 chr19:2800192 A/T cg19676328 chr12:49525230 TUBA1B -0.37 -6.04 -0.31 4e-9 Total cholesterol levels; LIHC cis rs10744422 0.858 rs4759389 chr12:123308615 A/G cg22842854 chr12:123319900 HIP1R -0.66 -8.61 -0.42 2.79e-16 Schizophrenia; LIHC trans rs1814175 0.527 rs10769595 chr11:49638212 A/G cg03929089 chr4:120376271 NA -0.68 -9.82 -0.47 3.14e-20 Height; LIHC trans rs11098499 0.863 rs9997631 chr4:120469995 C/G cg25214090 chr10:38739885 LOC399744 0.57 9.01 0.44 1.46e-17 Corneal astigmatism; LIHC cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg03735888 chr19:58951602 ZNF132 0.39 6.56 0.33 1.96e-10 Uric acid clearance; LIHC cis rs8141529 0.732 rs5752798 chr22:29181868 A/G cg02153584 chr22:29168773 CCDC117 0.56 9.15 0.44 5.27e-18 Lymphocyte counts; LIHC cis rs7116495 1.000 rs34390540 chr11:71558532 C/A cg26138937 chr11:71823887 C11orf51 0.64 6.17 0.32 1.91e-9 Severe influenza A (H1N1) infection; LIHC cis rs11676348 0.791 rs4133195 chr2:218951245 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.42 5.85 0.3 1.16e-8 Ulcerative colitis; LIHC cis rs16854884 0.673 rs34379944 chr3:143785766 G/A cg06585982 chr3:143692056 C3orf58 0.53 6.45 0.33 3.76e-10 Economic and political preferences (feminism/equality); LIHC trans rs3780486 0.846 rs10124479 chr9:33136233 T/G cg20290983 chr6:43655470 MRPS18A 1.19 30.89 0.86 5.55e-101 IgG glycosylation; LIHC cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg27170947 chr2:26402098 FAM59B 0.66 8.34 0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg17971929 chr21:40555470 PSMG1 0.88 10.85 0.51 9.15e-24 Cognitive function; LIHC cis rs2404602 0.622 rs11637296 chr15:77207885 C/A cg23625390 chr15:77176239 SCAPER -0.49 -8.2 -0.41 5.07e-15 Blood metabolite levels; LIHC cis rs758324 0.853 rs6865911 chr5:131204659 A/G cg06307176 chr5:131281290 NA 0.41 5.84 0.3 1.22e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7582720 1.000 rs72934519 chr2:203939640 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.87 0.3 1.05e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1552244 0.554 rs6762594 chr3:9995516 G/A cg21531657 chr3:10005747 TMEM111 0.39 5.96 0.31 6.15e-9 Alzheimer's disease; LIHC cis rs7412746 0.658 rs4970986 chr1:150907955 A/G cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs11190604 1.000 rs4919464 chr10:102221195 A/G cg07080220 chr10:102295463 HIF1AN 0.49 6.81 0.35 4.29e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg01339444 chr6:118972232 C6orf204 0.59 5.82 0.3 1.32e-8 Diastolic blood pressure; LIHC cis rs921968 0.643 rs526134 chr2:219402371 G/A cg18887096 chr2:219472410 PLCD4 0.36 6.44 0.33 4.12e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 8.87e-33 Prudent dietary pattern; LIHC cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg11905131 chr22:24372483 LOC391322 -0.71 -10.63 -0.5 5.57e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs60871478 0.945 rs4719279 chr7:813618 T/C cg04727924 chr7:799746 HEATR2 -0.58 -8.57 -0.42 3.65e-16 Cerebrospinal P-tau181p levels; LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg02782426 chr3:40428986 ENTPD3 0.34 6.4 0.33 5e-10 Renal cell carcinoma; LIHC trans rs9388451 0.626 rs1343116 chr6:126069702 C/A cg05039488 chr6:79577232 IRAK1BP1 -0.66 -10.88 -0.51 6.98e-24 Brugada syndrome; LIHC cis rs7100689 0.646 rs11202751 chr10:82147802 G/A cg00277334 chr10:82204260 NA -0.58 -7.53 -0.38 4.6e-13 Post bronchodilator FEV1; LIHC trans rs2270927 0.510 rs35984318 chr5:75573566 T/G cg13563193 chr19:33072644 PDCD5 0.95 9.22 0.45 3.18e-18 Mean corpuscular volume; LIHC cis rs7647973 0.577 rs6446247 chr3:49102001 A/T cg20833759 chr3:49053208 WDR6;DALRD3 0.54 6.47 0.33 3.43e-10 Menarche (age at onset); LIHC cis rs7707921 0.846 rs4293895 chr5:81425592 T/C cg15871215 chr5:81402204 ATG10 -0.63 -6.3 -0.32 9.36e-10 Breast cancer; LIHC cis rs9811920 0.609 rs7636447 chr3:99612677 G/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.65e-9 Total body bone mineral density; LIHC cis rs2153535 0.560 rs9379214 chr6:8480870 T/C cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs12893668 0.608 rs12889721 chr14:104034863 C/T cg24130564 chr14:104152367 KLC1 -0.56 -9.45 -0.46 5.39e-19 Reticulocyte count; LIHC cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.71 -0.57 1.46e-30 Alzheimer's disease; LIHC cis rs6545883 0.894 rs7572603 chr2:61552145 C/G cg15711740 chr2:61764176 XPO1 0.42 5.77 0.3 1.82e-8 Tuberculosis; LIHC cis rs6442522 0.568 rs3773461 chr3:15494658 C/G cg16303742 chr3:15540471 COLQ 0.4 6.46 0.33 3.66e-10 Uric acid levels; LIHC cis rs17125944 0.505 rs2274275 chr14:53235728 G/T cg00686598 chr14:53173677 PSMC6 1.29 15.75 0.65 2.06e-42 Alzheimer's disease (late onset); LIHC cis rs8062405 1.000 rs72793812 chr16:28840381 A/G cg16576597 chr16:28551801 NUPR1 0.37 5.82 0.3 1.37e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2404602 0.647 rs2404600 chr15:77173557 C/T cg23625390 chr15:77176239 SCAPER -0.53 -8.8 -0.43 6.96e-17 Blood metabolite levels; LIHC cis rs6582630 0.537 rs10785436 chr12:38461040 G/C cg26384229 chr12:38710491 ALG10B 0.63 8.79 0.43 7.51e-17 Drug-induced liver injury (flucloxacillin); LIHC cis rs2439831 0.681 rs1549523 chr15:43624189 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.91 17.43 0.69 3.8e-49 Lung cancer in ever smokers; LIHC cis rs963731 0.649 rs297152 chr2:39326734 G/T cg04010122 chr2:39346883 SOS1 -0.61 -6.1 -0.31 2.83e-9 Corticobasal degeneration; LIHC cis rs7589728 0.514 rs78204719 chr2:88460747 G/C cg04511125 chr2:88470314 THNSL2 0.98 10.04 0.48 5.71e-21 Plasma clusterin levels; LIHC cis rs7312774 0.618 rs35435903 chr12:107346572 G/C cg16260113 chr12:107380972 MTERFD3 0.85 11.13 0.52 9.19e-25 Severe influenza A (H1N1) infection; LIHC cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg10802521 chr3:52805072 NEK4 0.43 6.98 0.35 1.5e-11 Bipolar disorder; LIHC cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg11764359 chr7:65958608 NA -0.68 -9.24 -0.45 2.64e-18 Aortic root size; LIHC cis rs6933660 0.721 rs2128945 chr6:151767907 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.61 9.88 0.47 1.98e-20 Menarche (age at onset); LIHC cis rs55882075 0.936 rs34646062 chr5:179186318 A/G cg14593053 chr5:179126677 CANX -0.42 -7.62 -0.38 2.44e-13 Monocyte percentage of white cells; LIHC cis rs6793245 0.845 rs4073796 chr3:38590849 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.48 -7.04 -0.36 1.03e-11 QT interval; LIHC cis rs12477438 0.520 rs2969379 chr2:99776686 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.38 0.64 5.93e-41 Chronic sinus infection; LIHC cis rs8072100 0.512 rs9674670 chr17:45386157 G/A cg08085267 chr17:45401833 C17orf57 -0.6 -8.77 -0.43 8.45e-17 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs9916302 0.784 rs34473775 chr17:37396201 G/T cg07936489 chr17:37558343 FBXL20 -0.8 -12.76 -0.57 9.38e-31 Glomerular filtration rate (creatinine); LIHC cis rs3008870 0.755 rs1925410 chr1:67365230 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.64 -10.58 -0.5 8.04e-23 Lymphocyte percentage of white cells; LIHC cis rs8017423 0.967 rs11845329 chr14:90727749 C/T cg14092571 chr14:90743983 NA -0.4 -6.27 -0.32 1.12e-9 Mortality in heart failure; LIHC cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs623264 0.920 rs671283 chr19:5470410 C/G cg03088458 chr19:5478473 NA 0.36 6.18 0.32 1.81e-9 Interleukin-2 receptor antagonist levels; LIHC cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs6089584 0.545 rs6089578 chr20:60554636 G/T cg06108461 chr20:60628389 TAF4 -0.52 -6.89 -0.35 2.62e-11 Body mass index; LIHC cis rs1190552 0.846 rs12883789 chr14:102954621 G/A cg18135206 chr14:102964638 TECPR2 0.4 5.76 0.3 1.86e-8 Blood protein levels; LIHC cis rs10751667 0.643 rs7479473 chr11:929111 C/T cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.54 0.33 2.22e-10 Bipolar disorder; LIHC cis rs3845702 0.736 rs72962575 chr2:180862133 C/G cg01881094 chr2:180872142 CWC22 1.12 9.94 0.47 1.24e-20 Schizophrenia; LIHC cis rs739401 0.611 rs417957 chr11:3046231 A/G cg20651018 chr11:3035856 CARS -0.37 -6.24 -0.32 1.29e-9 Longevity; LIHC cis rs875971 0.964 rs6978721 chr7:65883204 A/G cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC trans rs941408 0.928 rs2260414 chr19:2796316 G/A cg19676328 chr12:49525230 TUBA1B -0.39 -6.4 -0.33 5e-10 Total cholesterol levels; LIHC cis rs1005277 0.522 rs9417256 chr10:37976990 A/G cg25427524 chr10:38739819 LOC399744 -0.62 -11.96 -0.54 8.58e-28 Extrinsic epigenetic age acceleration; LIHC cis rs600806 0.854 rs367586 chr1:109850122 C/A cg08911820 chr1:110026001 ATXN7L2 -0.58 -6.85 -0.35 3.35e-11 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs1999335 chr21:46670613 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 7.51 0.38 5.13e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs875971 0.964 rs6978721 chr7:65883204 A/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs7106204 0.514 rs7107321 chr11:24259879 T/C ch.11.24196551F chr11:24239977 NA 0.75 9.4 0.45 7.88e-19 Response to Homoharringtonine (cytotoxicity); LIHC cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC cis rs2270431 1 rs2270431 chr14:75270635 T/C cg08847533 chr14:75593920 NEK9 0.47 7.26 0.37 2.54e-12 Neuroticism; LIHC cis rs796364 0.806 rs1106400 chr2:201004089 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.66 -7.66 -0.38 1.96e-13 Schizophrenia; LIHC cis rs3806843 1.000 rs10057161 chr5:140156831 C/T cg19875535 chr5:140030758 IK 0.37 5.95 0.31 6.64e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg20818283 chr2:191399100 TMEM194B -0.45 -6.17 -0.32 1.95e-9 Pulse pressure; LIHC cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg08280861 chr8:58055591 NA 0.54 7.78 0.39 8.47e-14 Developmental language disorder (linguistic errors); LIHC cis rs1670533 1.000 rs6821725 chr4:1060360 C/G cg27284194 chr4:1044797 NA 0.59 8.71 0.43 1.37e-16 Recombination rate (females); LIHC cis rs11190604 1.000 rs2489045 chr10:102344754 C/T cg07080220 chr10:102295463 HIF1AN 0.54 7.59 0.38 3e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6121246 0.567 rs6120937 chr20:30219721 C/T cg13852791 chr20:30311386 BCL2L1 0.78 6.77 0.34 5.69e-11 Mean corpuscular hemoglobin; LIHC trans rs4650994 1.000 rs4650995 chr1:178517316 C/T cg05059571 chr16:84539110 KIAA1609 -0.38 -6.35 -0.32 6.95e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07145255 chr5:59995354 DEPDC1B 0.46 7.55 0.38 4.1e-13 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11502736 chr1:179923845 CEP350 0.39 6.05 0.31 3.82e-9 Cognitive function; LIHC cis rs2836974 0.583 rs9981884 chr21:40585633 G/A cg11644478 chr21:40555479 PSMG1 0.46 6.44 0.33 4.06e-10 Cognitive function; LIHC trans rs4927850 1.000 rs4927704 chr3:195738228 C/T cg16724585 chr3:197361211 NA -0.47 -6.25 -0.32 1.21e-9 Pancreatic cancer; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg09455208 chr3:40491958 NA 0.39 8.05 0.4 1.41e-14 Renal cell carcinoma; LIHC cis rs1003719 0.843 rs1003721 chr21:38492657 T/G cg10648535 chr21:38446584 PIGP;TTC3 0.73 11.45 0.53 6.48e-26 Eye color traits; LIHC cis rs78456975 1.000 rs11898988 chr2:1560336 G/A cg01028140 chr2:1542097 TPO -0.54 -6.44 -0.33 4.01e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2153535 0.580 rs718502 chr6:8527400 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.52 0.42 5.15e-16 Motion sickness; LIHC cis rs9916302 0.904 rs6503519 chr17:37706578 A/G cg00129232 chr17:37814104 STARD3 -0.41 -6.6 -0.34 1.53e-10 Glomerular filtration rate (creatinine); LIHC cis rs11677370 0.603 rs11675498 chr2:3850943 G/T cg17052675 chr2:3827356 NA -0.53 -6.78 -0.34 5.2e-11 Type 2 diabetes; LIHC cis rs1003719 0.788 rs2156076 chr21:38452634 G/T cg10648535 chr21:38446584 PIGP;TTC3 0.75 11.63 0.53 1.49e-26 Eye color traits; LIHC cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg09904177 chr6:26538194 HMGN4 0.57 11.34 0.52 1.58e-25 Intelligence (multi-trait analysis); LIHC cis rs116095464 0.558 rs7725227 chr5:233517 G/A cg22857025 chr5:266934 NA -1.48 -18.11 -0.7 6.78e-52 Breast cancer; LIHC cis rs7772486 0.754 rs702306 chr6:145991029 T/C cg23711669 chr6:146136114 FBXO30 -0.74 -13.25 -0.58 1.24e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs1023500 0.573 rs4822088 chr22:42470589 G/C cg00645731 chr22:42541494 CYP2D7P1 0.4 6.25 0.32 1.2e-9 Schizophrenia; LIHC cis rs9828933 0.678 rs704366 chr3:63871648 A/G cg16258503 chr3:63850278 ATXN7;THOC7 0.69 8.64 0.42 2.15e-16 Type 2 diabetes; LIHC cis rs11098499 0.754 rs1980025 chr4:120252806 A/G cg09307838 chr4:120376055 NA -0.72 -11.55 -0.53 2.74e-26 Corneal astigmatism; LIHC cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg03806693 chr22:41940476 POLR3H -1.11 -13.58 -0.59 6.5e-34 Vitiligo; LIHC cis rs36051895 0.623 rs72703608 chr9:5258127 A/G cg02405213 chr9:5042618 JAK2 -0.62 -9.75 -0.47 5.61e-20 Pediatric autoimmune diseases; LIHC cis rs11608355 0.545 rs12818120 chr12:109901916 C/T cg05360138 chr12:110035743 NA 0.97 11.05 0.51 1.72e-24 Neuroticism; LIHC cis rs2346177 0.519 rs4563285 chr2:46669944 C/G cg02822958 chr2:46747628 ATP6V1E2 0.47 7.37 0.37 1.31e-12 HDL cholesterol; LIHC cis rs911119 1.000 rs34897231 chr20:23620268 A/G cg16589663 chr20:23618590 CST3 0.77 8.21 0.41 4.66e-15 Chronic kidney disease; LIHC cis rs600806 0.713 rs12140694 chr1:109998386 C/T cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.61 -0.38 2.77e-13 Intelligence (multi-trait analysis); LIHC cis rs9522267 0.535 rs9522303 chr13:112237301 T/C cg10483660 chr13:112241077 NA -0.21 -5.74 -0.3 2.08e-8 Hepatitis; LIHC trans rs1005277 0.579 rs2472178 chr10:38384750 T/C cg27523141 chr10:43048294 ZNF37B 0.37 6.4 0.33 5.12e-10 Extrinsic epigenetic age acceleration; LIHC cis rs28735056 0.967 rs4799092 chr18:77608203 C/G cg20368463 chr18:77673604 PQLC1 -0.38 -6.67 -0.34 1.04e-10 Schizophrenia; LIHC cis rs9303401 0.527 rs7224468 chr17:56749943 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.89 11.16 0.52 7.3e-25 Cognitive test performance; LIHC cis rs2760061 0.626 rs634106 chr1:228121548 C/T cg02753203 chr1:228287806 NA -0.47 -7.63 -0.38 2.3e-13 Diastolic blood pressure; LIHC cis rs9399135 0.933 rs7755680 chr6:135294259 A/G cg24558204 chr6:135376177 HBS1L 0.41 6.76 0.34 6.02e-11 Red blood cell count; LIHC trans rs7676999 0.592 rs77126424 chr4:116853112 C/A cg25881869 chr10:114609298 LOC143188 0.45 6.61 0.34 1.51e-10 Age-related macular degeneration; LIHC cis rs1728785 0.792 rs1111502 chr16:68581209 A/G cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs7937890 0.900 rs7118682 chr11:14274550 T/G cg23387056 chr11:14280742 SPON1 0.45 6.28 0.32 1.03e-9 Mitochondrial DNA levels; LIHC cis rs7618501 0.633 rs55751738 chr3:49972101 A/G cg21467203 chr3:49911342 NA -0.45 -8.11 -0.4 9.32e-15 Intelligence (multi-trait analysis); LIHC trans rs1945213 0.625 rs7128190 chr11:55858550 A/T cg15704280 chr7:45808275 SEPT13 0.59 7.68 0.38 1.71e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs116095464 0.558 rs28635197 chr5:279071 T/C cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.65e-22 Breast cancer; LIHC cis rs8177253 1.000 rs8177247 chr3:133479499 T/G cg12373951 chr3:133503437 NA 0.7 12.49 0.56 9.26e-30 Iron status biomarkers; LIHC cis rs9420 0.961 rs527528 chr11:57433327 C/T cg19752551 chr11:57585705 CTNND1 -0.53 -7.46 -0.37 7.23e-13 Schizophrenia; LIHC cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.16e-14 Prudent dietary pattern; LIHC cis rs2191566 0.960 rs12232810 chr19:44525122 A/G cg18700516 chr19:44507157 ZNF230 -0.35 -5.86 -0.3 1.12e-8 Acute lymphoblastic leukemia (childhood); LIHC cis rs1865760 0.786 rs1436308 chr6:25939567 T/G cg03264133 chr6:25882463 NA -0.42 -6.26 -0.32 1.17e-9 Height; LIHC cis rs796364 0.806 rs78527234 chr2:200913453 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.79 -8.79 -0.43 7.5e-17 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19835839 chr12:120966954 COQ5 0.48 6.43 0.33 4.39e-10 Lung function (FEV1/FVC); LIHC cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg18252515 chr7:66147081 NA -1.24 -16.11 -0.66 7.76e-44 Diabetic kidney disease; LIHC cis rs16854884 0.657 rs35085196 chr3:143712210 C/T cg06585982 chr3:143692056 C3orf58 0.63 8.85 0.43 4.62e-17 Economic and political preferences (feminism/equality); LIHC cis rs265548 0.510 rs28415068 chr19:17910582 T/A cg16744531 chr19:17905626 B3GNT3 0.55 8.15 0.4 6.8e-15 Tumor biomarkers; LIHC cis rs951366 0.789 rs823095 chr1:205679239 G/A cg14893161 chr1:205819251 PM20D1 0.68 9.83 0.47 3.12e-20 Menarche (age at onset); LIHC cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg13271783 chr10:134563150 INPP5A -0.6 -7.18 -0.36 4.32e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs9916302 0.904 rs755500 chr17:37409865 C/T cg03013999 chr17:37608204 MED1 0.35 5.88 0.3 9.63e-9 Glomerular filtration rate (creatinine); LIHC cis rs244731 0.959 rs6556307 chr5:176641434 C/T cg17509989 chr5:176798049 RGS14 0.65 6.24 0.32 1.29e-9 Urate levels in lean individuals; LIHC cis rs12365397 0.925 rs11037342 chr11:43218424 G/T cg16667275 chr11:43333495 API5 -0.44 -6.2 -0.32 1.6e-9 Migraine; LIHC cis rs6750047 0.585 rs4670808 chr2:38267794 A/G cg07380506 chr2:38303506 CYP1B1 0.57 7.24 0.36 2.97e-12 Cutaneous malignant melanoma;Melanoma; LIHC cis rs2777491 0.915 rs7178777 chr15:41634588 C/A cg18705301 chr15:41695430 NDUFAF1 -0.59 -9.03 -0.44 1.25e-17 Ulcerative colitis; LIHC cis rs965469 0.947 rs6037529 chr20:3261006 C/T cg25506879 chr20:3388711 C20orf194 -0.58 -6.98 -0.35 1.52e-11 IFN-related cytopenia; LIHC trans rs1499614 1.000 rs2659913 chr7:66157336 T/A cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs9814567 0.806 rs55835132 chr3:134325256 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.4 -0.45 7.89e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8017423 1.000 rs2183189 chr14:90670057 A/G cg04374321 chr14:90722782 PSMC1 0.71 13.52 0.59 1.11e-33 Mortality in heart failure; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg13024018 chr3:133380790 TOPBP1 -0.38 -6.37 -0.33 6.12e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg23758822 chr17:41437982 NA 0.94 17.75 0.69 1.91e-50 Menopause (age at onset); LIHC cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg11764359 chr7:65958608 NA -0.56 -5.87 -0.3 1.03e-8 Diabetic kidney disease; LIHC cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg02034447 chr16:89574710 SPG7 0.49 7.36 0.37 1.35e-12 Multiple myeloma (IgH translocation); LIHC cis rs8017423 0.935 rs59179255 chr14:90691773 A/C cg04374321 chr14:90722782 PSMC1 0.73 13.82 0.6 7.8e-35 Mortality in heart failure; LIHC cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg20607798 chr8:58055168 NA 0.73 8.06 0.4 1.25e-14 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.862 rs10250544 chr7:65766561 A/G cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs9768139 0.708 rs11771764 chr7:158119871 A/G cg25566285 chr7:158114605 PTPRN2 0.23 6.24 0.32 1.33e-9 Calcium levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03694868 chr2:62684297 NA 0.46 6.65 0.34 1.19e-10 Lung function (FEV1/FVC); LIHC cis rs1577917 0.958 rs2324840 chr6:86557620 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -8.07 -0.4 1.23e-14 Response to antipsychotic treatment; LIHC cis rs9303401 0.659 rs12150264 chr17:56939927 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.97 13.45 0.59 2.18e-33 Cognitive test performance; LIHC cis rs7408868 1.000 rs757472 chr19:15273221 T/C cg14696996 chr19:15285081 NOTCH3 0.48 6.39 0.33 5.28e-10 Pulse pressure; LIHC cis rs10504229 1.000 rs73591706 chr8:58195633 C/T cg20607798 chr8:58055168 NA 0.59 6.8 0.35 4.58e-11 Developmental language disorder (linguistic errors); LIHC cis rs597539 0.652 rs604524 chr11:68629929 G/A cg04772025 chr11:68637568 NA 0.48 6.45 0.33 3.81e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs67460515 0.531 rs13315565 chr3:160754626 G/C cg03342759 chr3:160939853 NMD3 -0.57 -8.14 -0.4 7.61e-15 Parkinson's disease; LIHC cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg05590025 chr7:65112418 INTS4L2 -0.64 -6.94 -0.35 1.96e-11 Diabetic kidney disease; LIHC cis rs6912958 0.678 rs9450744 chr6:88280529 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.78 -0.39 8.89e-14 Monocyte percentage of white cells; LIHC cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg11764359 chr7:65958608 NA 0.58 6.09 0.31 2.95e-9 Diabetic kidney disease; LIHC cis rs6952808 0.501 rs4721429 chr7:2171704 T/C cg04267008 chr7:1944627 MAD1L1 -0.49 -7.55 -0.38 3.91e-13 Bipolar disorder and schizophrenia; LIHC cis rs11122272 0.733 rs2749700 chr1:231522734 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -11.01 -0.51 2.42e-24 Hemoglobin concentration; LIHC cis rs4684776 1.000 rs7616608 chr3:11429793 C/T cg00170343 chr3:11313890 ATG7 -0.42 -5.76 -0.3 1.91e-8 Small vessel stroke; LIHC cis rs1707322 0.682 rs12041197 chr1:46104464 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.61 0.38 2.75e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11673344 0.864 rs7247589 chr19:37510781 G/A cg27390819 chr19:37464633 NA -0.51 -6.21 -0.32 1.57e-9 Obesity-related traits; LIHC cis rs477895 0.838 rs35090903 chr11:64000598 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 9.46 0.46 5.08e-19 Mean platelet volume; LIHC cis rs933688 1.000 rs6867219 chr5:90718008 T/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 19.7 0.73 2.92e-58 Smoking behavior; LIHC cis rs7613875 0.654 rs3774751 chr3:50209053 G/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.51 -7.48 -0.37 6.29e-13 Body mass index; LIHC cis rs4901869 0.966 rs12893803 chr14:59329655 T/C cg02291164 chr14:59296302 NA 0.46 5.73 0.3 2.18e-8 Panic disorder; LIHC cis rs2933343 1.000 rs2630252 chr3:128624772 T/C cg25356066 chr3:128598488 ACAD9 0.52 6.76 0.34 6.13e-11 IgG glycosylation; LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg02782426 chr3:40428986 ENTPD3 0.35 6.48 0.33 3.17e-10 Renal cell carcinoma; LIHC cis rs7223966 1.000 rs15637 chr17:61772050 C/G cg05941027 chr17:61774174 LIMD2 0.3 5.99 0.31 5.18e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg00612595 chr21:47717864 NA -0.35 -5.87 -0.3 1.01e-8 Testicular germ cell tumor; LIHC cis rs10751667 0.666 rs7395321 chr11:940280 C/T ch.11.42038R chr11:967971 AP2A2 0.55 10.04 0.48 5.67e-21 Alzheimer's disease (late onset); LIHC cis rs10744422 1.000 rs3817094 chr12:123332032 T/C cg25930673 chr12:123319894 HIP1R -0.93 -12.35 -0.56 3.04e-29 Schizophrenia; LIHC cis rs311392 0.902 rs1511147 chr8:55091227 C/T cg11783602 chr8:55087084 NA -0.29 -5.91 -0.3 8.38e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs4555082 0.834 rs2735819 chr14:105713449 C/T cg10792982 chr14:105748885 BRF1 0.5 6.55 0.33 2.12e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs5758511 0.680 rs1001586 chr22:42670293 G/T cg00645731 chr22:42541494 CYP2D7P1 0.52 8.29 0.41 2.59e-15 Birth weight; LIHC trans rs1814175 0.527 rs7110797 chr11:49644096 T/C cg18944383 chr4:111397179 ENPEP 0.32 7.24 0.36 3.02e-12 Height; LIHC trans rs334353 0.785 rs334365 chr9:101929151 G/A cg06788856 chr17:1821969 NA -0.32 -6.11 -0.31 2.74e-9 Age-related macular degeneration; LIHC cis rs6570726 0.755 rs2092296 chr6:145893684 A/C cg13319975 chr6:146136371 FBXO30 -0.39 -6.37 -0.33 6.08e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21576151 chr16:561444 RAB11FIP3 0.47 6.69 0.34 8.87e-11 Pancreatic cancer; LIHC cis rs1801251 1.000 rs895430 chr2:233725483 C/A cg08000102 chr2:233561755 GIGYF2 -0.76 -11.54 -0.53 3.15e-26 Coronary artery disease; LIHC cis rs11792861 0.890 rs3087979 chr9:111781779 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.52 0.42 5.08e-16 Menarche (age at onset); LIHC cis rs9443189 0.570 rs504446 chr6:76326939 T/C cg01950844 chr6:76311363 SENP6 0.88 10.98 0.51 3.09e-24 Prostate cancer; LIHC trans rs1814175 0.645 rs28445479 chr11:50047999 A/G cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs12928939 0.769 rs12445161 chr16:71741928 C/T cg03805757 chr16:71968109 PKD1L3 -0.66 -7.51 -0.38 5.1e-13 Post bronchodilator FEV1; LIHC cis rs722599 0.748 rs7145173 chr14:75351647 G/A cg08847533 chr14:75593920 NEK9 -0.55 -8.87 -0.43 4.2e-17 IgG glycosylation; LIHC cis rs2637266 0.846 rs2637263 chr10:78322442 G/A cg18941641 chr10:78392320 NA 0.27 5.86 0.3 1.11e-8 Pulmonary function; LIHC cis rs12477438 0.520 rs13022329 chr2:99731189 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 13.94 0.6 2.84e-35 Chronic sinus infection; LIHC cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.69 9.94 0.47 1.3e-20 Lymphocyte counts; LIHC cis rs4718428 0.705 rs10267335 chr7:66403220 G/T cg12165864 chr7:66369176 NA -0.46 -6.76 -0.34 5.92e-11 Corneal structure; LIHC cis rs4631830 0.863 rs2611489 chr10:51524889 C/T cg20129853 chr10:51489980 NA -0.43 -9.44 -0.45 5.99e-19 Prostate-specific antigen levels; LIHC cis rs244293 0.965 rs7224560 chr17:53176539 G/C cg19360675 chr17:53046073 COX11;STXBP4 0.5 7.47 0.37 6.93e-13 Menarche (age at onset); LIHC cis rs1552244 0.882 rs55840655 chr3:10042690 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs8141529 0.515 rs16986861 chr22:29343188 G/C cg15103426 chr22:29168792 CCDC117 0.44 6.14 0.32 2.26e-9 Lymphocyte counts; LIHC cis rs2976388 0.609 rs2572907 chr8:143801938 G/A cg13446199 chr8:143762866 PSCA -0.2 -5.85 -0.3 1.12e-8 Urinary tract infection frequency; LIHC cis rs2997447 0.723 rs61776623 chr1:26474490 A/G cg19633962 chr1:26362018 EXTL1 -0.69 -6.47 -0.33 3.44e-10 QRS complex (12-leadsum); LIHC cis rs523522 0.923 rs1048830 chr12:120882217 G/T cg27279351 chr12:120934652 DYNLL1 0.65 11.23 0.52 4.17e-25 High light scatter reticulocyte count; LIHC trans rs6489882 0.867 rs4766674 chr12:113365201 A/C cg10175203 chr3:128143634 NA -0.39 -6.33 -0.32 7.55e-10 Chronic lymphocytic leukemia; LIHC cis rs17401966 0.931 rs3748577 chr1:10357406 C/T cg15208524 chr1:10270712 KIF1B -0.43 -6.54 -0.33 2.3e-10 Hepatocellular carcinoma; LIHC cis rs17739167 0.550 rs17687976 chr15:42234824 A/G cg20935245 chr15:42234343 EHD4 -0.42 -7.82 -0.39 6.41e-14 Monocyte count; LIHC trans rs916888 0.773 rs538628 chr17:44787313 G/C cg12297030 chr17:43662878 NA -0.63 -6.08 -0.31 3.3e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7715806 0.500 rs17563974 chr5:75004175 G/A cg19683494 chr5:74908142 NA 0.68 7.91 0.39 3.55e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs2707844 chr7:66059509 G/A cg18252515 chr7:66147081 NA -1.33 -18.21 -0.7 2.75e-52 Diabetic kidney disease; LIHC cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg13607699 chr17:42295918 UBTF -0.58 -10.44 -0.49 2.44e-22 Total body bone mineral density; LIHC cis rs7589728 0.516 rs79815126 chr2:88488270 G/A cg04511125 chr2:88470314 THNSL2 0.95 8.87 0.43 4.19e-17 Plasma clusterin levels; LIHC cis rs597539 0.652 rs686877 chr11:68637169 G/A cg06028808 chr11:68637592 NA 0.43 5.84 0.3 1.21e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6762 0.748 rs5030780 chr11:838110 C/T cg07691484 chr11:842764 TSPAN4;POLR2L -0.77 -10.23 -0.48 1.32e-21 Mean platelet volume; LIHC cis rs12477438 0.501 rs6751927 chr2:99740175 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs12701220 0.655 rs9638973 chr7:1133678 A/G cg04498913 chr7:1135747 C7orf50 0.43 6.9 0.35 2.51e-11 Bronchopulmonary dysplasia; LIHC cis rs477895 0.713 rs7952318 chr11:63961242 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 9.23 0.45 2.79e-18 Mean platelet volume; LIHC cis rs4073582 0.595 rs555360 chr11:65960061 T/C cg16950941 chr11:66035639 RAB1B -0.56 -8.35 -0.41 1.67e-15 Gout; LIHC cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.53 7.43 0.37 8.61e-13 Bipolar disorder; LIHC cis rs12960505 0.506 rs11664123 chr18:50967028 T/C cg24270629 chr18:50823537 DCC -0.47 -6.63 -0.34 1.29e-10 Intelligence (multi-trait analysis); LIHC cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg24004478 chr7:855632 UNC84A 0.49 8.1 0.4 9.55e-15 Perceived unattractiveness to mosquitoes; LIHC cis rs1865760 1.000 rs9467636 chr6:25919549 A/C cg17691542 chr6:26056736 HIST1H1C 0.42 6.27 0.32 1.08e-9 Height; LIHC cis rs7216064 1.000 rs4271626 chr17:65930133 G/A cg12091567 chr17:66097778 LOC651250 -0.61 -8.64 -0.42 2.19e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs6938574 0.672 rs6569520 chr6:128365034 C/G cg03735592 chr6:138821354 NHSL1 -0.34 -6.35 -0.32 6.86e-10 Menarche (age at onset); LIHC cis rs3008870 0.755 rs1024230 chr1:67512920 A/C cg02640540 chr1:67518911 SLC35D1 0.67 13.13 0.58 3.52e-32 Lymphocyte percentage of white cells; LIHC cis rs2303759 0.918 rs2288480 chr19:49867016 C/G cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 9.01 0.44 1.5e-17 Multiple sclerosis; LIHC cis rs7474896 0.609 rs11011336 chr10:37985316 A/G cg25427524 chr10:38739819 LOC399744 -0.49 -7.22 -0.36 3.35e-12 Obesity (extreme); LIHC cis rs12477438 0.520 rs2516829 chr2:99773201 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.21 21.25 0.75 1.75e-64 Chronic sinus infection; LIHC cis rs7937682 0.575 rs7950926 chr11:111776437 G/C cg09085632 chr11:111637200 PPP2R1B 0.94 14.2 0.61 2.62e-36 Primary sclerosing cholangitis; LIHC cis rs798554 0.757 rs2644312 chr7:2841164 G/A cg13628971 chr7:2884303 GNA12 0.52 7.67 0.38 1.81e-13 Height; LIHC cis rs13108904 0.846 rs4974574 chr4:1224811 A/G cg00684032 chr4:1343700 KIAA1530 0.46 6.73 0.34 7.27e-11 Obesity-related traits; LIHC cis rs2153535 0.580 rs1119688 chr6:8460850 T/C cg07606381 chr6:8435919 SLC35B3 0.8 11.69 0.53 9e-27 Motion sickness; LIHC trans rs875971 0.508 rs10950045 chr7:66066373 T/C cg26939375 chr7:64535504 NA -0.43 -7.34 -0.37 1.62e-12 Aortic root size; LIHC cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg06238570 chr21:40685208 BRWD1 -0.54 -8.92 -0.43 2.8e-17 Cognitive function; LIHC cis rs1865721 0.771 rs62092763 chr18:73128623 T/G cg26385618 chr18:73139727 C18orf62 -0.32 -8.5 -0.42 6.16e-16 Intelligence; LIHC cis rs9457247 1.000 rs416131 chr6:167406544 A/C cg12798992 chr6:167411361 FGFR1OP -0.62 -10.55 -0.5 1.01e-22 Crohn's disease; LIHC cis rs6429082 0.755 rs291367 chr1:235690800 G/A cg26050004 chr1:235667680 B3GALNT2 0.46 7.29 0.37 2.15e-12 Adiposity; LIHC cis rs67311347 0.866 rs1454491 chr3:40352647 C/G cg13409248 chr3:40428643 ENTPD3 0.37 5.79 0.3 1.61e-8 Renal cell carcinoma; LIHC cis rs9486719 1.000 rs2499816 chr6:96878206 C/T cg06623918 chr6:96969491 KIAA0776 0.73 7.18 0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs3820068 0.705 rs57440988 chr1:15879034 T/C cg17385448 chr1:15911702 AGMAT 0.41 6.83 0.35 3.82e-11 Systolic blood pressure; LIHC cis rs6463523 0.898 rs66892628 chr7:759374 T/A cg11064039 chr7:766100 PRKAR1B;HEATR2 1.03 18.24 0.7 2.12e-52 Subjective well-being; LIHC cis rs769267 0.740 rs2965185 chr19:19525792 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.47 6.09 0.31 3.07e-9 Tonsillectomy; LIHC cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg17747265 chr1:1875780 NA -0.6 -11.58 -0.53 2.21e-26 Body mass index; LIHC cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg10360323 chr17:41437877 NA 0.4 6.08 0.31 3.29e-9 Menopause (age at onset); LIHC trans rs62103177 0.525 rs4799117 chr18:77756604 G/A cg05926928 chr17:57297772 GDPD1 -0.57 -6.45 -0.33 3.87e-10 Opioid sensitivity; LIHC trans rs61931739 0.534 rs73103090 chr12:34098801 C/T cg26384229 chr12:38710491 ALG10B 0.47 6.49 0.33 3.01e-10 Morning vs. evening chronotype; LIHC cis rs7937890 0.532 rs2256884 chr11:14476402 A/T cg02886208 chr11:14281011 SPON1 -0.46 -6.58 -0.34 1.75e-10 Mitochondrial DNA levels; LIHC cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg07414643 chr4:187882934 NA 0.22 5.78 0.3 1.67e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9596863 1.000 rs35429587 chr13:54406523 T/A ch.13.53330881F chr13:54432880 NA 0.44 5.98 0.31 5.48e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs8062405 1.000 rs4788101 chr16:28867804 C/T cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03412097 chr11:95524327 FAM76B;CEP57 -0.58 -6.77 -0.34 5.47e-11 Systolic blood pressure; LIHC cis rs6840360 1.000 rs4696291 chr4:152631637 G/A cg22705602 chr4:152727874 NA -0.32 -6.92 -0.35 2.19e-11 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24449302 chr15:66679100 MAP2K1 0.63 8.34 0.41 1.84e-15 Lung function (FEV1/FVC); LIHC cis rs7617773 0.815 rs6793150 chr3:48351560 G/A cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs1941023 0.503 rs4939349 chr11:60135880 G/A cg08716584 chr11:60157161 MS4A7 -0.36 -8.18 -0.4 5.66e-15 Congenital heart disease (maternal effect); LIHC cis rs2070488 0.775 rs4407366 chr3:38521425 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.64 10.11 0.48 3.3e-21 Electrocardiographic conduction measures; LIHC cis rs35110281 0.782 rs2329442 chr21:45041790 T/C cg04455712 chr21:45112962 RRP1B 0.47 7.85 0.39 5.34e-14 Mean corpuscular volume; LIHC cis rs13191362 1.000 rs13201023 chr6:162981381 C/G cg06582575 chr6:163149167 PACRG;PARK2 0.65 5.79 0.3 1.59e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9733 0.596 rs17606613 chr1:150683015 C/T cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs7945705 0.692 rs2742470 chr11:9004002 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.47 -8.45 -0.42 8.37e-16 Hemoglobin concentration; LIHC cis rs7647973 0.769 rs4974081 chr3:49070499 A/G cg07636037 chr3:49044803 WDR6 -0.75 -8.92 -0.43 2.89e-17 Menarche (age at onset); LIHC cis rs2073499 0.872 rs58051625 chr3:50278717 G/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.74 7.82 0.39 6.7e-14 Schizophrenia; LIHC trans rs1814175 0.645 rs599890 chr11:49711718 G/A cg03929089 chr4:120376271 NA -0.86 -16.58 -0.67 9.62e-46 Height; LIHC cis rs903552 0.800 rs12903584 chr15:101999369 G/A cg25677261 chr15:102009856 PCSK6 -0.43 -5.9 -0.3 8.96e-9 Diabetic kidney disease; LIHC cis rs968567 0.705 rs174575 chr11:61602003 C/G cg27386326 chr11:61587980 NA 0.41 6.13 0.31 2.39e-9 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs950776 0.518 rs4886571 chr15:78833758 G/A cg06917634 chr15:78832804 PSMA4 -0.93 -14.35 -0.61 7.22e-37 Sudden cardiac arrest; LIHC cis rs644799 0.526 rs568120 chr11:95578734 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.66 10.66 0.5 4.11e-23 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs3617 0.625 rs2240917 chr3:52851137 T/C cg11645453 chr3:52864694 ITIH4 0.21 5.86 0.3 1.08e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs2839186 0.872 rs13052233 chr21:47707284 G/T cg12379764 chr21:47803548 PCNT -0.6 -8.79 -0.43 7.28e-17 Testicular germ cell tumor; LIHC cis rs2075165 1.000 rs2075165 chr1:156215899 G/A cg20302342 chr1:156215951 PAQR6 0.33 6.08 0.31 3.3e-9 Tonsillectomy; LIHC cis rs655641 1.000 rs600743 chr11:85686223 A/T cg09030501 chr11:85779252 PICALM -0.51 -6.01 -0.31 4.88e-9 Platelet count; LIHC cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg18876405 chr7:65276391 NA 0.55 9.42 0.45 7.17e-19 Calcium levels; LIHC cis rs7474896 0.507 rs2474555 chr10:38465220 G/C cg25427524 chr10:38739819 LOC399744 -0.51 -6.83 -0.35 3.84e-11 Obesity (extreme); LIHC cis rs225245 0.755 rs226432 chr17:34043825 G/A cg05299278 chr17:33885742 SLFN14 -0.23 -6.21 -0.32 1.56e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs875971 0.545 rs17138149 chr7:65693180 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.56 0.38 3.67e-13 Aortic root size; LIHC cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs77861329 1.000 rs28659792 chr3:52107966 G/C cg08692210 chr3:52188851 WDR51A 0.82 7.39 0.37 1.17e-12 Macrophage inflammatory protein 1b levels; LIHC cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg18357526 chr6:26021779 HIST1H4A 1.06 15.66 0.65 4.61e-42 Intelligence (multi-trait analysis); LIHC cis rs600806 0.888 rs592107 chr1:109848726 A/T cg08911820 chr1:110026001 ATXN7L2 -0.57 -6.78 -0.34 5.14e-11 Intelligence (multi-trait analysis); LIHC cis rs807029 0.577 rs701835 chr10:102762127 A/G cg25179470 chr10:102756915 LZTS2 0.44 6.02 0.31 4.54e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7116495 0.786 rs610004 chr11:71797939 C/T cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs875971 1.000 rs7792762 chr7:66004138 T/C cg12463550 chr7:65579703 CRCP 0.42 5.97 0.31 5.87e-9 Aortic root size; LIHC trans rs2275606 0.920 rs13206260 chr6:146914151 G/A cg22017777 chr5:111506984 EPB41L4A 0.43 6.03 0.31 4.15e-9 Leprosy; LIHC cis rs7095944 0.614 rs4962697 chr10:126447545 G/C cg08799069 chr10:126477246 METTL10 -0.37 -6.48 -0.33 3.23e-10 Asthma; LIHC cis rs1799949 1.000 rs8077486 chr17:41212805 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.75 0.3 2.03e-8 Menopause (age at onset); LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg06656553 chr16:89960601 TCF25 -0.48 -6.09 -0.31 3.09e-9 Skin colour saturation; LIHC cis rs6964587 0.967 rs34863529 chr7:91644341 C/G cg17063962 chr7:91808500 NA 1.03 19.74 0.73 1.88e-58 Breast cancer; LIHC cis rs6121246 0.909 rs7272062 chr20:30259145 A/G cg13852791 chr20:30311386 BCL2L1 0.96 9.81 0.47 3.45e-20 Mean corpuscular hemoglobin; LIHC cis rs3845702 0.736 rs56401468 chr2:180857757 C/T cg01881094 chr2:180872142 CWC22 1.15 10.17 0.48 2.1e-21 Schizophrenia; LIHC cis rs7520050 0.966 rs61783220 chr1:46335312 G/A cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg18252515 chr7:66147081 NA -1.29 -16.89 -0.67 5.55e-47 Diabetic kidney disease; LIHC cis rs10751667 0.961 rs7479171 chr11:926809 G/A cg06064525 chr11:970664 AP2A2 -0.48 -11.95 -0.54 9.76e-28 Alzheimer's disease (late onset); LIHC cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 2.97e-30 Menopause (age at onset); LIHC cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.09 -0.31 3.09e-9 Total body bone mineral density; LIHC trans rs2727020 0.576 rs11040223 chr11:49034633 G/T cg03929089 chr4:120376271 NA -0.45 -6.89 -0.35 2.64e-11 Coronary artery disease; LIHC cis rs7833986 0.501 rs2667983 chr8:56894087 T/G cg23139584 chr8:56987506 RPS20;SNORD54 0.87 8.76 0.43 9.08e-17 Height; LIHC cis rs8017423 0.967 rs59006192 chr14:90706456 C/T cg04374321 chr14:90722782 PSMC1 0.75 14.41 0.61 4.1e-37 Mortality in heart failure; LIHC cis rs10504073 0.669 rs341801 chr8:50037784 A/G cg00325661 chr8:49890786 NA 0.32 7.26 0.37 2.64e-12 Blood metabolite ratios; LIHC trans rs56011263 0.687 rs4690293 chr4:706101 A/G cg12575136 chr18:32820987 ZNF397 0.48 7.18 0.36 4.33e-12 White blood cell count; LIHC cis rs8084351 0.539 rs6508188 chr18:50570638 T/G cg24270629 chr18:50823537 DCC 0.41 6.43 0.33 4.23e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs1799949 0.965 rs8070179 chr17:41202688 G/A cg05368731 chr17:41323189 NBR1 0.69 11.44 0.53 6.89e-26 Menopause (age at onset); LIHC cis rs9389248 0.690 rs728030 chr6:135246294 G/T cg24558204 chr6:135376177 HBS1L -0.53 -8.48 -0.42 7.09e-16 High light scatter reticulocyte percentage of red cells; LIHC cis rs703842 0.642 rs11536137 chr12:58056426 C/A cg18357645 chr12:58087776 OS9 -0.51 -7.78 -0.39 8.53e-14 Multiple sclerosis; LIHC trans rs4332037 0.950 rs62442895 chr7:1936938 G/A cg11693508 chr17:37793320 STARD3 0.73 7.53 0.38 4.48e-13 Bipolar disorder; LIHC cis rs2228479 0.850 rs17232630 chr16:89851179 C/T cg00800038 chr16:89945340 TCF25 -0.6 -8.65 -0.42 2.09e-16 Skin colour saturation; LIHC trans rs9914544 0.933 rs11871889 chr17:18771425 T/C cg04702396 chr17:15466718 FAM18B2 0.43 6.43 0.33 4.26e-10 Educational attainment (years of education); LIHC cis rs908922 0.627 rs11590073 chr1:152500810 C/T cg23254163 chr1:152506842 NA 0.23 5.8 0.3 1.53e-8 Hair morphology; LIHC cis rs2279817 0.863 rs28481933 chr1:18026277 A/G cg21791023 chr1:18019539 ARHGEF10L 0.43 6.49 0.33 3.01e-10 Neuroticism; LIHC cis rs1707322 0.821 rs11211182 chr1:46240170 G/A cg06784218 chr1:46089804 CCDC17 0.39 6.56 0.33 1.99e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs600806 0.854 rs11102974 chr1:109886371 G/A cg23091122 chr1:110024289 SYPL2 -0.44 -5.75 -0.3 2.03e-8 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.561 rs6060750 chr20:34596371 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -8.53 -0.42 4.67e-16 Total cholesterol levels; LIHC trans rs2243480 1.000 rs34560516 chr7:65404092 A/T cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg23782820 chr8:58130467 NA 0.34 5.91 0.3 8.1e-9 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.735 rs2790881 chr1:231534181 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.94e-23 Hemoglobin concentration; LIHC cis rs5015933 0.902 rs2270746 chr9:128121592 C/T cg14078157 chr9:128172775 NA 0.38 6.31 0.32 8.71e-10 Body mass index; LIHC cis rs888194 0.628 rs9888325 chr12:110037413 G/T cg05360138 chr12:110035743 NA 0.42 5.94 0.31 6.99e-9 Neuroticism; LIHC cis rs4555082 0.874 rs2816606 chr14:105716034 C/T cg06808227 chr14:105710500 BRF1 -0.5 -6.19 -0.32 1.74e-9 Mean platelet volume;Platelet distribution width; LIHC trans rs2000813 0.857 rs8092097 chr18:47102503 C/T cg01564661 chr14:105942636 CRIP2 0.34 6.3 0.32 9.26e-10 Coronary artery disease; LIHC cis rs7312933 0.558 rs11181467 chr12:42765250 C/T cg01256987 chr12:42539512 GXYLT1 -0.36 -5.91 -0.3 8.5e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs8180040 0.966 rs3736177 chr3:47451411 C/T cg16586182 chr3:47516702 SCAP 0.59 11.42 0.53 8.54e-26 Colorectal cancer; LIHC cis rs9303280 0.840 rs12939457 chr17:38032188 T/C cg11212589 chr17:38028394 ZPBP2 0.35 7.19 0.36 4.05e-12 Self-reported allergy; LIHC cis rs6952808 0.500 rs3800902 chr7:2144378 C/T cg04267008 chr7:1944627 MAD1L1 -0.53 -8.35 -0.41 1.67e-15 Bipolar disorder and schizophrenia; LIHC cis rs6748734 1.000 rs6724662 chr2:241831560 A/G cg08694578 chr2:241835147 C2orf54 -0.51 -7.04 -0.36 1.09e-11 Urinary metabolites; LIHC cis rs34779708 0.897 rs4934716 chr10:35369299 A/G cg03585969 chr10:35415529 CREM 0.85 12.9 0.57 2.75e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.01 12.83 0.57 4.9e-31 Alzheimer's disease; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg12321073 chr6:43138853 SRF -0.38 -6.28 -0.32 1.05e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg18357526 chr6:26021779 HIST1H4A 0.6 8.4 0.41 1.18e-15 Blood metabolite levels; LIHC cis rs11031096 0.711 rs11031156 chr11:4179021 C/T cg18678763 chr11:4115507 RRM1 -0.42 -6.02 -0.31 4.5e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs17685 0.712 rs28506984 chr7:75763484 A/G cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs477895 0.639 rs35858916 chr11:63950529 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 9.63 0.46 1.44e-19 Mean platelet volume; LIHC cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg11062466 chr8:58055876 NA 0.5 7.04 0.36 1.04e-11 Developmental language disorder (linguistic errors); LIHC cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg12310025 chr6:25882481 NA -0.48 -5.88 -0.3 9.85e-9 Intelligence (multi-trait analysis); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg06397510 chr1:32403634 PTP4A2 -0.46 -6.75 -0.34 6.29e-11 Systolic blood pressure; LIHC cis rs7829975 0.840 rs572366 chr8:8578794 A/T cg06636001 chr8:8085503 FLJ10661 0.43 6.89 0.35 2.67e-11 Mood instability; LIHC cis rs15676 0.783 rs3829057 chr9:131567982 A/G cg00228799 chr9:131580591 ENDOG 0.47 6.58 0.34 1.78e-10 Blood metabolite levels; LIHC cis rs7618501 0.633 rs2526751 chr3:50064867 T/C cg24110177 chr3:50126178 RBM5 0.48 7.77 0.39 9.14e-14 Intelligence (multi-trait analysis); LIHC cis rs1348850 0.914 rs3813259 chr2:178257214 G/A cg27490568 chr2:178487706 NA 0.36 5.84 0.3 1.23e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2075371 0.966 rs2244690 chr7:133987039 A/G cg20476274 chr7:133979776 SLC35B4 0.75 12.53 0.56 6.44e-30 Mean platelet volume; LIHC cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg00166722 chr3:10149974 C3orf24 0.47 5.79 0.3 1.58e-8 Alzheimer's disease; LIHC cis rs10845606 0.505 rs7299416 chr12:12831568 C/T cg04607235 chr12:12878440 APOLD1 0.41 6.04 0.31 3.96e-9 Systemic lupus erythematosus; LIHC trans rs1005277 0.589 rs2749624 chr10:38529865 A/G cg23533926 chr12:111358616 MYL2 -0.36 -6.9 -0.35 2.52e-11 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.71 0.38 1.35e-13 Prudent dietary pattern; LIHC cis rs875971 0.862 rs801209 chr7:66019390 G/T cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.34e-9 Aortic root size; LIHC cis rs919433 0.680 rs6434930 chr2:198369370 A/G cg10820045 chr2:198174542 NA 0.53 8.59 0.42 3.24e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg04013166 chr16:89971882 TCF25 0.61 8.09 0.4 1.04e-14 Skin colour saturation; LIHC cis rs17685 0.753 rs1859791 chr7:75786043 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1814175 0.650 rs6486000 chr11:49659090 T/A cg03929089 chr4:120376271 NA -0.82 -15.0 -0.63 1.91e-39 Height; LIHC cis rs1580019 0.713 rs2167274 chr7:32524844 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.42 6.14 0.32 2.3e-9 Cognitive ability; LIHC cis rs7572733 0.534 rs2060488 chr2:198751637 T/G cg03934865 chr2:198174659 NA 0.45 6.49 0.33 2.96e-10 Dermatomyositis; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg00975115 chr16:30958403 FBXL19 0.43 6.23 0.32 1.39e-9 Bilirubin levels; LIHC cis rs801193 1.000 rs10274773 chr7:66133578 G/A cg18876405 chr7:65276391 NA -0.43 -7.37 -0.37 1.31e-12 Aortic root size; LIHC cis rs7267979 0.966 rs2227892 chr20:25264814 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs1892700 1.000 rs16990773 chr21:35014316 C/T cg14850771 chr21:34775459 IFNGR2 -0.44 -5.86 -0.3 1.11e-8 Educational attainment; LIHC cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.39e-8 Menopause (age at onset); LIHC cis rs7727544 0.735 rs274559 chr5:131720070 A/G cg07395648 chr5:131743802 NA 0.32 6.58 0.34 1.74e-10 Blood metabolite levels; LIHC cis rs6582630 0.537 rs8189533 chr12:38391068 A/G cg26384229 chr12:38710491 ALG10B 0.82 9.81 0.47 3.52e-20 Drug-induced liver injury (flucloxacillin); LIHC cis rs13126513 0.519 rs12641768 chr4:100558594 C/A cg05468953 chr4:100565104 NA 0.35 7.31 0.37 1.95e-12 Metabolite levels (MHPG); LIHC cis rs10751667 0.643 rs10902244 chr11:949981 A/G cg06064525 chr11:970664 AP2A2 -0.56 -15.02 -0.63 1.66e-39 Alzheimer's disease (late onset); LIHC cis rs477692 0.571 rs10764890 chr10:131347163 G/A cg05714579 chr10:131428358 MGMT 0.4 6.44 0.33 3.96e-10 Response to temozolomide; LIHC cis rs10876993 0.890 rs12302351 chr12:58062590 T/C cg18357645 chr12:58087776 OS9 0.53 8.79 0.43 7.4e-17 Celiac disease or Rheumatoid arthritis; LIHC cis rs2412488 1.000 rs6857024 chr4:54242283 G/A cg22241045 chr4:54363911 LNX1 -0.45 -7.11 -0.36 6.72e-12 DNA methylation (variation); LIHC cis rs7911264 0.572 rs7071912 chr10:94416229 T/G cg00519463 chr10:94352821 KIF11 -0.45 -6.26 -0.32 1.19e-9 Inflammatory bowel disease; LIHC cis rs4660306 0.677 rs781060 chr1:45934166 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC 0.62 6.64 0.34 1.21e-10 Homocysteine levels; LIHC trans rs1814175 0.817 rs1319547 chr11:49916705 C/T cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs875971 1.000 rs6979382 chr7:65886375 C/T cg11764359 chr7:65958608 NA 0.91 17.08 0.68 9.57e-48 Aortic root size; LIHC cis rs7707921 0.752 rs6882565 chr5:81356421 G/A cg15871215 chr5:81402204 ATG10 -0.62 -6.78 -0.34 5.34e-11 Breast cancer; LIHC cis rs7124681 0.584 rs12226590 chr11:47571808 T/C cg20307385 chr11:47447363 PSMC3 0.81 12.32 0.55 4.07e-29 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC cis rs9790314 0.747 rs1841526 chr3:160834682 A/G cg03342759 chr3:160939853 NMD3 -0.68 -8.31 -0.41 2.36e-15 Morning vs. evening chronotype; LIHC cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg13395646 chr4:1353034 KIAA1530 -0.63 -8.99 -0.44 1.66e-17 Obesity-related traits; LIHC cis rs2797160 0.837 rs1739364 chr6:126022383 A/G cg05901451 chr6:126070800 HEY2 -0.5 -8.42 -0.41 1.07e-15 Endometrial cancer; LIHC cis rs1577917 0.958 rs67024565 chr6:86553997 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.19 -0.52 5.38e-25 Response to antipsychotic treatment; LIHC cis rs801193 1.000 rs3800812 chr7:66223461 T/C cg11764359 chr7:65958608 NA 0.71 10.63 0.5 5.5e-23 Aortic root size; LIHC cis rs7589728 0.514 rs12465706 chr2:88467459 C/A cg07952391 chr2:88470173 THNSL2 0.8 7.68 0.38 1.64e-13 Plasma clusterin levels; LIHC cis rs9326248 0.520 rs236919 chr11:117095361 A/G cg01368799 chr11:117014884 PAFAH1B2 0.64 9.91 0.47 1.58e-20 Blood protein levels; LIHC cis rs7100689 0.646 rs1890889 chr10:82090827 G/T cg01528321 chr10:82214614 TSPAN14 0.77 10.24 0.48 1.2e-21 Post bronchodilator FEV1; LIHC cis rs10493773 0.630 rs3753790 chr1:86174772 T/C cg17807903 chr1:86174739 ZNHIT6 -0.63 -12.45 -0.56 1.37e-29 Urate levels in overweight individuals; LIHC cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg16822855 chr3:40428330 ENTPD3 -0.31 -5.86 -0.3 1.09e-8 Renal cell carcinoma; LIHC cis rs503341 0.756 rs11231591 chr11:63587986 G/T cg04362095 chr11:63592001 C11orf84 -0.68 -13.57 -0.59 7.11e-34 Pulse pressure; LIHC cis rs8103278 0.507 rs3745802 chr19:46271177 G/T cg12641515 chr19:46296257 DMWD 0.43 6.71 0.34 8.15e-11 Coronary artery disease; LIHC cis rs7131987 0.903 rs2194520 chr12:29423712 C/T cg00204748 chr12:29376779 FAR2 0.42 7.62 0.38 2.58e-13 QT interval; LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg26338869 chr17:61819248 STRADA 0.61 8.85 0.43 4.64e-17 Prudent dietary pattern; LIHC cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg06238570 chr21:40685208 BRWD1 0.6 6.95 0.35 1.89e-11 Cognitive function; LIHC cis rs7940866 0.834 rs10894302 chr11:130861994 C/T cg12179176 chr11:130786555 SNX19 0.61 8.77 0.43 8.64e-17 Schizophrenia; LIHC cis rs7618501 1.000 rs695238 chr3:49869158 A/C cg21467203 chr3:49911342 NA -0.4 -6.98 -0.35 1.56e-11 Intelligence (multi-trait analysis); LIHC cis rs9596863 0.898 rs9563178 chr13:54373714 C/A ch.13.53330881F chr13:54432880 NA 0.43 5.8 0.3 1.53e-8 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg09913183 chr17:42254507 C17orf65;ASB16 -0.82 -12.65 -0.56 2.31e-30 Total body bone mineral density; LIHC cis rs2153535 0.580 rs6421948 chr6:8531020 T/C cg21535247 chr6:8435926 SLC35B3 0.65 8.49 0.42 6.54e-16 Motion sickness; LIHC cis rs9303401 0.704 rs7359501 chr17:56641200 C/T cg05425664 chr17:57184151 TRIM37 -0.5 -7.37 -0.37 1.3e-12 Cognitive test performance; LIHC cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg27211696 chr2:191398769 TMEM194B 0.63 10.54 0.5 1.12e-22 Pulse pressure; LIHC cis rs2070488 1.000 rs2268757 chr3:38505853 C/T cg24069376 chr3:38537580 EXOG 0.42 7.76 0.39 9.78e-14 Electrocardiographic conduction measures; LIHC cis rs2625529 0.730 rs12908882 chr15:72437572 G/A cg16672083 chr15:72433130 SENP8 -0.3 -5.77 -0.3 1.77e-8 Red blood cell count; LIHC cis rs7312933 0.703 rs10880259 chr12:42558003 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 8.01 0.4 1.81e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs1994135 0.669 rs2121831 chr12:33697674 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.58 0.34 1.81e-10 Resting heart rate; LIHC cis rs12134245 0.747 rs17501512 chr1:92012481 C/G cg07090678 chr1:91966139 CDC7 -0.47 -6.32 -0.32 7.99e-10 Breast cancer; LIHC cis rs35110281 0.712 rs162345 chr21:44954155 T/G cg04455712 chr21:45112962 RRP1B 0.44 7.48 0.37 6.53e-13 Mean corpuscular volume; LIHC cis rs2806561 0.765 rs641808 chr1:23514123 T/G cg12483005 chr1:23474871 LUZP1 0.44 6.99 0.35 1.49e-11 Height; LIHC cis rs7618501 0.966 rs7372966 chr3:49788969 T/C cg21467203 chr3:49911342 NA 0.39 6.64 0.34 1.2e-10 Intelligence (multi-trait analysis); LIHC cis rs11971779 0.680 rs10261557 chr7:139099037 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.47e-21 Diisocyanate-induced asthma; LIHC cis rs600626 0.529 rs10899115 chr11:75471849 A/G cg24262691 chr11:75473276 NA 0.43 6.49 0.33 3.08e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs7715806 0.500 rs17649266 chr5:75001252 C/T cg00601450 chr5:74908170 NA -0.59 -7.24 -0.36 3e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11673344 0.864 rs2562606 chr19:37520530 G/A cg27390819 chr19:37464633 NA -0.52 -6.34 -0.32 7.35e-10 Obesity-related traits; LIHC cis rs17106184 0.551 rs72896949 chr1:50837939 G/A cg07174182 chr1:51127561 FAF1 -0.44 -5.89 -0.3 9.24e-9 Type 2 diabetes; LIHC trans rs9929218 0.906 rs4783571 chr16:68806778 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC trans rs801193 0.839 rs12534943 chr7:66070520 A/G cg26939375 chr7:64535504 NA -0.43 -7.27 -0.37 2.46e-12 Aortic root size; LIHC cis rs2737618 0.722 rs2737673 chr1:200081710 T/C cg21825944 chr1:200113062 NR5A2 -0.38 -6.19 -0.32 1.71e-9 Uric acid levels; LIHC cis rs3204270 0.639 rs7215738 chr17:79659847 C/T cg18367735 chr17:79674897 NA 0.68 8.0 0.4 1.9e-14 Dental caries; LIHC cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg11764359 chr7:65958608 NA 0.57 6.03 0.31 4.16e-9 Diabetic kidney disease; LIHC cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg17971929 chr21:40555470 PSMG1 -0.4 -6.09 -0.31 3.04e-9 Menarche (age at onset); LIHC cis rs950776 0.722 rs471889 chr15:78870235 T/C cg06917634 chr15:78832804 PSMA4 -0.59 -7.98 -0.4 2.3e-14 Sudden cardiac arrest; LIHC cis rs9871864 1.000 rs9862452 chr3:20354712 C/T cg00235661 chr3:20228976 SGOL1 -0.31 -5.93 -0.31 7.42e-9 Behavioural disinhibition (generation interaction); LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg00969680 chr1:113466087 AFARP1;SLC16A1 0.64 6.61 0.34 1.5e-10 Mean platelet volume; LIHC cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg22907277 chr7:1156413 C7orf50 0.43 6.15 0.32 2.2e-9 Longevity;Endometriosis; LIHC cis rs2859741 0.967 rs575939 chr1:37513854 T/C cg09363841 chr1:37513479 NA -0.19 -6.08 -0.31 3.17e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs9733 0.544 rs72700902 chr1:150633347 C/T cg17724175 chr1:150552817 MCL1 0.49 9.97 0.47 9.91e-21 Tonsillectomy; LIHC cis rs77106637 0.929 rs74333814 chr11:72457487 C/T cg03713592 chr11:72463424 ARAP1 1.17 10.46 0.49 2.17e-22 Type 2 diabetes; LIHC trans rs2727020 0.617 rs1917311 chr11:49422665 C/T cg18944383 chr4:111397179 ENPEP 0.25 6.21 0.32 1.51e-9 Coronary artery disease; LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.59 -8.57 -0.42 3.59e-16 Lymphocyte counts; LIHC cis rs1823913 1.000 rs1823913 chr2:192118047 C/T cg12404831 chr2:192114017 MYO1B 0.33 6.62 0.34 1.39e-10 Obesity-related traits; LIHC cis rs9611565 0.512 rs139560 chr22:42194962 A/G cg06481639 chr22:41940642 POLR3H -0.61 -5.78 -0.3 1.69e-8 Vitiligo; LIHC cis rs1008375 0.897 rs67455495 chr4:17665238 A/T cg16339924 chr4:17578868 LAP3 -0.48 -6.31 -0.32 8.49e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs637571 0.522 rs28578718 chr11:65748400 C/A cg02202077 chr11:65769826 EIF1AD;BANF1 0.4 6.02 0.31 4.51e-9 Eosinophil percentage of white cells; LIHC cis rs11030122 0.635 rs10835540 chr11:4071429 T/A cg18678763 chr11:4115507 RRM1 -0.52 -7.5 -0.38 5.68e-13 Mean platelet volume;Platelet distribution width; LIHC cis rs10744422 0.528 rs6489245 chr12:123360151 G/A cg22842854 chr12:123319900 HIP1R -0.63 -7.38 -0.37 1.19e-12 Schizophrenia; LIHC cis rs8062405 1.000 rs4451951 chr16:28836205 T/C cg07451762 chr16:28383216 NA 0.33 6.15 0.32 2.14e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4665809 1.000 rs4665305 chr2:26313524 C/T cg04944784 chr2:26401820 FAM59B -0.64 -8.23 -0.41 4.02e-15 Gut microbiome composition (summer); LIHC cis rs61990749 0.544 rs2544566 chr14:78181738 C/G cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.81 -0.39 6.91e-14 Fibroblast growth factor basic levels; LIHC cis rs1355223 0.867 rs7925421 chr11:34681677 G/A cg11058730 chr11:34937778 PDHX;APIP -0.42 -5.77 -0.3 1.77e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2153535 0.580 rs4404802 chr6:8442052 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs9790314 1.000 rs1382426 chr3:161045933 G/A cg03342759 chr3:160939853 NMD3 -0.69 -8.39 -0.41 1.25e-15 Morning vs. evening chronotype; LIHC cis rs17685 0.753 rs11972240 chr7:75694079 A/C cg16684958 chr7:75615977 POR 0.48 7.91 0.39 3.61e-14 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs6600671 0.899 rs2319971 chr1:121226982 A/C cg09829573 chr1:144692074 NBPF9 -0.4 -6.78 -0.34 5.4e-11 Hip geometry; LIHC cis rs1008375 0.931 rs2098151 chr4:17577490 T/C cg16339924 chr4:17578868 LAP3 0.45 6.09 0.31 2.96e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs769267 0.930 rs3794990 chr19:19610030 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.2 0.32 1.58e-9 Tonsillectomy; LIHC cis rs8062405 0.754 rs28410083 chr16:28631360 A/T cg07451762 chr16:28383216 NA -0.38 -6.43 -0.33 4.24e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs763121 0.853 rs138716 chr22:39146527 C/T cg06022373 chr22:39101656 GTPBP1 0.7 12.68 0.57 1.77e-30 Menopause (age at onset); LIHC cis rs35306767 0.855 rs2050944 chr10:918910 T/C cg20503657 chr10:835505 NA 1.07 12.48 0.56 9.98e-30 Eosinophil percentage of granulocytes; LIHC trans rs61931739 0.517 rs10844815 chr12:34245150 G/A cg26384229 chr12:38710491 ALG10B 0.57 7.3 0.37 2.08e-12 Morning vs. evening chronotype; LIHC cis rs8180040 0.553 rs7620997 chr3:47214122 C/T cg16586182 chr3:47516702 SCAP 0.47 8.25 0.41 3.48e-15 Colorectal cancer; LIHC cis rs7520050 1.000 rs7540699 chr1:46338585 A/G cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.35e-10 Red blood cell count;Reticulocyte count; LIHC cis rs738322 0.967 rs132971 chr22:38561911 T/G cg17652424 chr22:38574118 PLA2G6 -0.2 -6.07 -0.31 3.4e-9 Cutaneous nevi; LIHC cis rs929354 0.772 rs1182432 chr7:157029176 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.98 -0.31 5.54e-9 Body mass index; LIHC cis rs17685 0.753 rs1639617 chr7:75701728 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6089584 0.861 rs2180302 chr20:60576369 A/G cg12751644 chr20:60527061 NA -0.36 -6.11 -0.31 2.68e-9 Body mass index; LIHC cis rs11971779 0.938 rs28477480 chr7:139036058 C/T cg07862535 chr7:139043722 LUC7L2 -0.68 -10.1 -0.48 3.58e-21 Diisocyanate-induced asthma; LIHC cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9399135 0.967 rs59329760 chr6:135342437 G/A cg22676075 chr6:135203613 NA 0.39 6.34 0.32 7.33e-10 Red blood cell count; LIHC cis rs7224737 1.000 rs739637 chr17:40280944 G/C cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs72781680 1.000 rs72781634 chr2:24199102 C/T cg08917208 chr2:24149416 ATAD2B 0.85 7.88 0.39 4.32e-14 Lymphocyte counts; LIHC cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg03806693 chr22:41940476 POLR3H -1.11 -13.22 -0.58 1.69e-32 Vitiligo; LIHC cis rs17685 0.712 rs4552844 chr7:75718095 A/G cg16684958 chr7:75615977 POR 0.52 8.68 0.42 1.65e-16 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs6489882 0.836 rs10774676 chr12:113362407 C/T cg10175203 chr3:128143634 NA -0.38 -6.21 -0.32 1.52e-9 Chronic lymphocytic leukemia; LIHC trans rs75804782 0.521 rs56373856 chr2:239437926 C/T cg01134436 chr17:81009848 B3GNTL1 0.74 6.4 0.33 5.04e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs11718455 1.000 rs11917515 chr3:44020237 A/G cg08738300 chr3:44038990 NA 0.51 8.87 0.43 4.13e-17 Coronary artery disease; LIHC cis rs11098499 0.955 rs4145951 chr4:120155817 A/G cg09307838 chr4:120376055 NA 0.75 10.9 0.51 6e-24 Corneal astigmatism; LIHC trans rs2727020 0.554 rs7111711 chr11:49557880 G/A cg18944383 chr4:111397179 ENPEP 0.35 8.17 0.4 6.1e-15 Coronary artery disease; LIHC cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg23758822 chr17:41437982 NA 0.91 16.84 0.67 8.86e-47 Menopause (age at onset); LIHC cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg25894440 chr7:65020034 NA -0.53 -6.11 -0.31 2.72e-9 Diabetic kidney disease; LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs1005277 0.579 rs2472181 chr10:38386764 T/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg00091569 chr3:40428383 ENTPD3 0.39 6.6 0.34 1.59e-10 Renal cell carcinoma; LIHC cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg19774624 chr17:42201019 HDAC5 -0.81 -12.7 -0.57 1.48e-30 Total body bone mineral density; LIHC cis rs6121246 0.909 rs6119729 chr20:30413163 A/G cg13852791 chr20:30311386 BCL2L1 -0.93 -9.74 -0.47 5.96e-20 Mean corpuscular hemoglobin; LIHC cis rs1030268 1.000 rs748754 chr7:133509069 G/A cg03336402 chr7:133662267 EXOC4 -0.52 -6.89 -0.35 2.74e-11 Intelligence (multi-trait analysis); LIHC cis rs7249142 0.549 rs10854012 chr19:19295719 C/T cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.41 -6.94 -0.35 1.95e-11 IgG glycosylation; LIHC cis rs7772486 0.790 rs3924498 chr6:146233338 A/T cg13319975 chr6:146136371 FBXO30 0.38 6.1 0.31 2.94e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs3845702 0.736 rs6433818 chr2:180810264 A/T cg01881094 chr2:180872142 CWC22 -1.17 -10.09 -0.48 3.91e-21 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14122300 chr14:69446504 ACTN1 0.42 6.16 0.32 2.05e-9 Pancreatic cancer; LIHC cis rs10751667 0.580 rs7396041 chr11:1001607 G/A cg06064525 chr11:970664 AP2A2 -0.44 -10.58 -0.5 8.06e-23 Alzheimer's disease (late onset); LIHC cis rs10744422 0.920 rs897393 chr12:123312051 A/G cg07706471 chr12:123319906 HIP1R 0.58 7.76 0.39 9.7e-14 Schizophrenia; LIHC cis rs1799949 0.965 rs8176310 chr17:41199913 T/C cg25072359 chr17:41440525 NA 0.4 6.39 0.33 5.36e-10 Menopause (age at onset); LIHC cis rs36051895 0.603 rs10974972 chr9:5130146 G/A cg02405213 chr9:5042618 JAK2 -0.64 -10.81 -0.5 1.22e-23 Pediatric autoimmune diseases; LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.38 0.76 5.19e-65 Height; LIHC cis rs4474465 0.850 rs4387376 chr11:78257662 T/C cg27205649 chr11:78285834 NARS2 0.39 5.94 0.31 6.97e-9 Alzheimer's disease (survival time); LIHC cis rs2243480 1.000 rs34192067 chr7:65887657 C/A cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs66573146 0.831 rs68111914 chr4:6986677 C/T cg15105060 chr4:7024189 TBC1D14 -0.75 -6.63 -0.34 1.3100000000000001e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs9951602 0.541 rs12454297 chr18:76654445 A/G cg02800362 chr5:177631904 HNRNPAB 0.66 10.5 0.49 1.52e-22 Obesity-related traits; LIHC cis rs74225573 1 rs74225573 chr1:11280994 T/C cg08854313 chr1:11322531 MTOR -0.81 -6.72 -0.34 7.63e-11 Corneal curvature; LIHC cis rs1046896 0.553 rs9893885 chr17:80837107 C/T cg19500275 chr17:80737654 TBCD 0.41 5.77 0.3 1.75e-8 Glycated hemoglobin levels; LIHC cis rs6088590 1.000 rs6087626 chr20:33347328 C/T cg08999081 chr20:33150536 PIGU 0.37 5.77 0.3 1.78e-8 Coronary artery disease; LIHC cis rs7264396 0.563 rs6060558 chr20:34271092 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.6 -8.23 -0.41 4.01e-15 Total cholesterol levels; LIHC cis rs7772486 0.790 rs2265917 chr6:146212285 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.86 -0.3 1.08e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9902453 1.000 rs4533340 chr17:28277951 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 12.07 0.55 3.43e-28 Coffee consumption (cups per day); LIHC cis rs9790314 1.000 rs4350933 chr3:160955879 G/T cg03342759 chr3:160939853 NMD3 -0.78 -11.07 -0.51 1.46e-24 Morning vs. evening chronotype; LIHC cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg21782813 chr7:2030301 MAD1L1 0.42 7.21 0.36 3.66e-12 Bipolar disorder and schizophrenia; LIHC cis rs9911578 0.935 rs12948039 chr17:57045184 C/T cg12560992 chr17:57184187 TRIM37 0.9 15.97 0.65 2.87e-43 Intelligence (multi-trait analysis); LIHC cis rs1005277 0.579 rs9418322 chr10:38377296 G/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs16854884 0.657 rs6783089 chr3:143738034 T/C cg06585982 chr3:143692056 C3orf58 0.55 7.17 0.36 4.79e-12 Economic and political preferences (feminism/equality); LIHC cis rs11025559 0.796 rs11603462 chr11:20412180 C/A cg19653624 chr11:20408972 PRMT3 -0.5 -6.39 -0.33 5.34e-10 Pursuit maintenance gain; LIHC cis rs6430585 0.527 rs2254780 chr2:136435526 C/T cg07169764 chr2:136633963 MCM6 0.59 7.25 0.36 2.81e-12 Corneal structure; LIHC cis rs7208859 0.673 rs11654331 chr17:29165017 A/G cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1018836 0.798 rs28568272 chr8:91652958 A/G cg16814680 chr8:91681699 NA -0.81 -12.9 -0.57 2.58e-31 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4450131 1.000 rs10444190 chr10:126375608 G/C cg20435097 chr10:126320824 FAM53B -0.51 -9.24 -0.45 2.71e-18 White blood cell count (basophil); LIHC cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg19723775 chr5:179050963 HNRNPH1 -0.4 -6.22 -0.32 1.43e-9 Lung cancer; LIHC trans rs10028773 0.515 rs9994651 chr4:120587803 C/T cg25214090 chr10:38739885 LOC399744 0.44 6.95 0.35 1.88e-11 Educational attainment; LIHC cis rs7523273 0.606 rs2796262 chr1:207915180 G/A cg22525895 chr1:207977042 MIR29B2 0.64 10.31 0.49 6.77e-22 Schizophrenia; LIHC cis rs9818758 0.607 rs11706189 chr3:49210833 C/A cg07636037 chr3:49044803 WDR6 -0.79 -7.91 -0.39 3.65e-14 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1843834 0.823 rs2129610 chr2:225505345 G/A cg22455342 chr2:225449267 CUL3 0.49 6.19 0.32 1.69e-9 IgE levels in asthmatics (D.p. specific); LIHC cis rs4595586 0.525 rs4768531 chr12:39417754 T/A cg26384229 chr12:38710491 ALG10B 0.5 5.98 0.31 5.66e-9 Morning vs. evening chronotype; LIHC cis rs9303401 0.659 rs7225896 chr17:56637337 T/C cg10487724 chr17:56770010 TEX14;RAD51C 1.01 14.01 0.6 1.53e-35 Cognitive test performance; LIHC cis rs796364 0.951 rs281793 chr2:200847990 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 8.92 0.43 2.96e-17 Schizophrenia; LIHC cis rs2370759 1.000 rs16933243 chr10:32615135 T/C cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs2758596 0.850 rs2241110 chr1:156172487 A/G cg24450063 chr1:156163899 SLC25A44 0.91 11.06 0.51 1.69e-24 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs826838 0.616 rs7977357 chr12:38626008 C/G cg26384229 chr12:38710491 ALG10B -0.51 -7.08 -0.36 8.34e-12 Heart rate; LIHC cis rs6964587 0.904 rs6465339 chr7:91570790 T/A cg17063962 chr7:91808500 NA -1.03 -20.51 -0.74 1.58e-61 Breast cancer; LIHC cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs240764 0.658 rs9485410 chr6:101261007 A/G cg09795085 chr6:101329169 ASCC3 0.42 5.81 0.3 1.46e-8 Neuroticism; LIHC cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg11890956 chr21:40555474 PSMG1 1.06 15.28 0.64 1.54e-40 Cognitive function; LIHC cis rs8180040 0.966 rs2291298 chr3:47555142 C/A cg27129171 chr3:47204927 SETD2 0.55 8.88 0.43 3.71e-17 Colorectal cancer; LIHC cis rs34172651 0.517 rs12927710 chr16:24790282 A/C cg00339695 chr16:24857497 SLC5A11 0.7 9.99 0.48 8.67e-21 Intelligence (multi-trait analysis); LIHC cis rs7613875 0.620 rs34312088 chr3:50032133 C/T cg05623727 chr3:50126028 RBM5 0.34 5.89 0.3 9.04e-9 Body mass index; LIHC cis rs10744422 0.920 rs10773657 chr12:123327900 C/A cg07706471 chr12:123319906 HIP1R -0.58 -7.68 -0.38 1.74e-13 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06037631 chr2:74942369 NA 0.41 6.06 0.31 3.62e-9 Cognitive function; LIHC cis rs240764 0.658 rs35168784 chr6:101183499 C/T cg09795085 chr6:101329169 ASCC3 -0.54 -7.76 -0.39 9.98e-14 Neuroticism; LIHC cis rs9816226 0.591 rs76880877 chr3:185802628 A/C cg00760338 chr3:185826511 ETV5 -0.71 -5.97 -0.31 5.86e-9 Obesity;Body mass index; LIHC cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg24209194 chr3:40518798 ZNF619 0.64 9.72 0.47 7.11e-20 Renal cell carcinoma; LIHC trans rs12478296 0.892 rs60545379 chr2:243034390 A/T cg01596870 chr19:55963115 NA -0.63 -8.36 -0.41 1.58e-15 Obesity-related traits; LIHC cis rs9399137 0.507 rs12663447 chr6:135317026 A/C cg24558204 chr6:135376177 HBS1L 0.61 10.4 0.49 3.53e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs7301016 0.846 rs11174568 chr12:63021157 T/C cg11441379 chr12:63026424 NA 0.63 6.28 0.32 1.01e-9 IgG glycosylation; LIHC cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.79 0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs311392 0.554 rs2671798 chr8:55104495 C/T cg20636351 chr8:55087400 NA -0.34 -7.0 -0.35 1.32e-11 Pelvic organ prolapse (moderate/severe); LIHC cis rs2067615 0.579 rs10778502 chr12:107090201 T/C cg15890332 chr12:107067104 RFX4 0.27 6.35 0.32 6.69e-10 Heart rate; LIHC cis rs2637266 1.000 rs2579750 chr10:78340260 C/G cg18941641 chr10:78392320 NA -0.28 -6.21 -0.32 1.55e-9 Pulmonary function; LIHC cis rs3862260 0.967 rs3862261 chr1:120160822 G/A cg11530693 chr1:120165357 ZNF697 0.47 7.53 0.38 4.59e-13 Systemic lupus erythematosus; LIHC cis rs921968 0.643 rs539451 chr2:219426972 T/C cg02985541 chr2:219472218 PLCD4 0.45 8.5 0.42 6.04e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs7937890 0.695 rs17557844 chr11:14262559 A/G cg02886208 chr11:14281011 SPON1 0.52 6.88 0.35 2.81e-11 Mitochondrial DNA levels; LIHC cis rs11583043 0.918 rs6693456 chr1:101424561 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 9.13 0.44 6.27e-18 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg02990361 chr1:107599529 PRMT6 -0.66 -11.0 -0.51 2.75e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9549367 0.713 rs56002882 chr13:113830694 T/C cg18105134 chr13:113819100 PROZ -0.76 -13.02 -0.58 9.81e-32 Platelet distribution width; LIHC cis rs7552404 1.000 rs437298 chr1:76113770 T/C cg22875332 chr1:76189707 ACADM -0.48 -6.95 -0.35 1.82e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs12477438 0.765 rs1115756 chr2:99659845 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC trans rs11098499 0.818 rs10008791 chr4:120431469 A/C cg25214090 chr10:38739885 LOC399744 0.59 9.55 0.46 2.59e-19 Corneal astigmatism; LIHC cis rs7909074 0.531 rs879343 chr10:45400707 G/T cg05187965 chr10:45406764 TMEM72 -0.24 -5.72 -0.3 2.38e-8 Mean corpuscular volume; LIHC cis rs921968 0.541 rs634590 chr2:219372768 C/A cg02176678 chr2:219576539 TTLL4 0.53 7.48 0.37 6.51e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg21016266 chr12:122356598 WDR66 0.52 7.23 0.36 3.09e-12 Mean corpuscular volume; LIHC cis rs10949834 0.504 rs150862 chr7:73524207 C/T cg07137043 chr7:73588983 EIF4H 0.59 7.39 0.37 1.17e-12 Verbal memory performance (residualized delayed recall change); LIHC cis rs8017423 0.647 rs12587362 chr14:90821227 G/T cg04374321 chr14:90722782 PSMC1 -0.49 -7.19 -0.36 4.05e-12 Mortality in heart failure; LIHC cis rs17106184 1.000 rs113704493 chr1:50892538 C/G cg07174182 chr1:51127561 FAF1 -0.57 -6.36 -0.32 6.65e-10 Type 2 diabetes; LIHC cis rs11105298 0.891 rs10858865 chr12:89846476 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.37 -0.37 1.25e-12 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs6456156 0.586 rs9457266 chr6:167482555 T/C cg12798992 chr6:167411361 FGFR1OP 0.43 6.57 0.33 1.85e-10 Primary biliary cholangitis; LIHC cis rs9309473 0.950 rs6546853 chr2:73833739 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.92 -0.35 2.17e-11 Metabolite levels; LIHC cis rs7487075 0.578 rs4768118 chr12:46784744 T/C cg23829395 chr12:46796953 NA 0.35 6.12 0.31 2.58e-9 Itch intensity from mosquito bite; LIHC cis rs3784262 1.000 rs4646586 chr15:58305344 C/A cg12031962 chr15:58353849 ALDH1A2 -0.35 -7.0 -0.35 1.34e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs6442522 0.780 rs13068150 chr3:15438941 C/G cg16303742 chr3:15540471 COLQ 0.38 5.99 0.31 5.28e-9 Uric acid levels; LIHC cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg12310025 chr6:25882481 NA -0.66 -8.3 -0.41 2.51e-15 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.872 rs1707308 chr1:46604315 G/A cg06787764 chr1:46668870 C1orf190;POMGNT1 0.41 5.97 0.31 5.94e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7662987 0.517 rs1311615 chr4:100012261 G/A cg12011299 chr4:100065546 ADH4 0.65 10.73 0.5 2.43e-23 Smoking initiation; LIHC cis rs1018836 0.892 rs13267237 chr8:91550820 T/C cg16814680 chr8:91681699 NA -0.61 -10.07 -0.48 4.53e-21 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7772486 0.875 rs13198450 chr6:146370524 C/A cg05347473 chr6:146136440 FBXO30 0.38 6.21 0.32 1.52e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg27170947 chr2:26402098 FAM59B 0.67 8.5 0.42 6.02e-16 Gut microbiome composition (summer); LIHC cis rs2562152 0.530 rs216604 chr16:112513 T/C cg02949481 chr16:131562 MPG 0.63 9.53 0.46 3e-19 Glioblastoma; LIHC trans rs4718428 0.705 rs11028 chr7:66276217 T/C cg10756647 chr7:56101905 PSPH 0.63 8.62 0.42 2.55e-16 Corneal structure; LIHC cis rs765787 0.530 rs2413782 chr15:45538490 A/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.45 -0.37 7.89e-13 Uric acid levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19098793 chr7:1609793 KIAA1908;PSMG3 -0.45 -6.55 -0.33 2.08e-10 Cognitive function; LIHC cis rs763121 0.815 rs9306328 chr22:39028913 C/T cg06544989 chr22:39130855 UNC84B 0.35 5.82 0.3 1.38e-8 Menopause (age at onset); LIHC cis rs9503598 0.636 rs6596978 chr6:3468878 C/T cg00476032 chr6:3446245 SLC22A23 0.4 7.67 0.38 1.78e-13 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs6570726 0.764 rs4263604 chr6:145916697 A/G cg23711669 chr6:146136114 FBXO30 0.65 10.89 0.51 6.68e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs12887734 0.569 rs66953418 chr14:104271470 G/A cg01849466 chr14:104193079 ZFYVE21 -0.39 -5.83 -0.3 1.27e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2749592 0.531 rs994804 chr10:37900140 A/C cg00409905 chr10:38381863 ZNF37A 0.51 8.54 0.42 4.38e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs151349 0.555 rs151343 chr20:57583298 C/G cg23907860 chr20:57583709 CTSZ 0.46 7.53 0.38 4.51e-13 Platelet distribution width; LIHC cis rs4819052 0.851 rs2838857 chr21:46681000 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 11.4 0.52 9.79e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs13631 0.728 rs10118245 chr9:139979592 C/T cg14289826 chr9:140003911 NA 0.4 6.61 0.34 1.48e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs17685 0.784 rs1637043 chr7:75699099 G/A cg01364799 chr7:75623366 TMEM120A -0.5 -7.48 -0.37 6.47e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9399135 1.000 rs6569988 chr6:135352303 C/A cg24558204 chr6:135376177 HBS1L 0.41 6.91 0.35 2.41e-11 Red blood cell count; LIHC cis rs1670533 1.000 rs10084849 chr4:1053586 T/C cg27284194 chr4:1044797 NA 0.6 8.94 0.44 2.5e-17 Recombination rate (females); LIHC cis rs12477438 0.501 rs9941561 chr2:99753829 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.21 21.25 0.75 1.75e-64 Chronic sinus infection; LIHC cis rs8058578 0.943 rs3747486 chr16:30786927 C/T cg00531865 chr16:30841666 NA -0.39 -5.92 -0.3 7.76e-9 Multiple myeloma; LIHC trans rs11098499 0.775 rs2002049 chr4:120257417 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.26 0.41 3.23e-15 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03226425 chr6:170151538 C6orf70;TCTE3 0.59 8.09 0.4 1.07e-14 Pancreatic cancer; LIHC cis rs10845606 1.000 rs11055013 chr12:12829037 T/C cg04607235 chr12:12878440 APOLD1 -0.72 -9.45 -0.45 5.69e-19 Systemic lupus erythematosus; LIHC cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg23758822 chr17:41437982 NA 0.94 18.0 0.7 1.99e-51 Menopause (age at onset); LIHC cis rs8072100 1.000 rs11870935 chr17:45732605 G/A cg08085267 chr17:45401833 C17orf57 0.58 8.55 0.42 4.29e-16 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs7395662 0.548 rs4882000 chr11:48546496 A/G cg15704280 chr7:45808275 SEPT13 -0.46 -6.9 -0.35 2.56e-11 HDL cholesterol; LIHC cis rs10911232 0.507 rs10911195 chr1:182993438 T/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.25 0.48 1.08e-21 Hypertriglyceridemia; LIHC cis rs1023500 1.000 rs6002554 chr22:42339095 T/C cg04733989 chr22:42467013 NAGA -0.51 -6.0 -0.31 5.15e-9 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08165151 chr6:88411075 NCRNA00120;AKIRIN2 0.45 6.59 0.34 1.68e-10 Cognitive function; LIHC cis rs9916302 0.752 rs9901219 chr17:37558369 T/G cg07936489 chr17:37558343 FBXL20 0.92 14.31 0.61 9.88e-37 Glomerular filtration rate (creatinine); LIHC cis rs9534288 0.699 rs1409432 chr13:46668302 C/T cg15192986 chr13:46630673 CPB2 -0.4 -5.89 -0.3 9.34e-9 Blood protein levels; LIHC cis rs6964587 0.626 rs10225241 chr7:91524940 A/G cg17063962 chr7:91808500 NA -0.61 -10.99 -0.51 2.93e-24 Breast cancer; LIHC cis rs2153535 0.580 rs2184583 chr6:8447808 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.69 0.43 1.55e-16 Motion sickness; LIHC trans rs2727020 0.675 rs7929401 chr11:49350832 C/A cg03929089 chr4:120376271 NA -0.65 -9.31 -0.45 1.62e-18 Coronary artery disease; LIHC cis rs1577917 0.771 rs4351223 chr6:86237797 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 12.0 0.54 6.38e-28 Response to antipsychotic treatment; LIHC cis rs753955 0.554 rs2031587 chr13:24417335 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.35 6.06 0.31 3.58e-9 Lung cancer; LIHC cis rs712039 0.652 rs853224 chr17:35791328 A/T cg16670864 chr17:35848621 DUSP14 0.35 5.84 0.3 1.2e-8 Tuberculosis; LIHC cis rs611744 0.967 rs695028 chr8:109239324 T/C cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg24693881 chr1:107596107 NA 0.56 9.78 0.47 4.41e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7715806 0.500 rs17649332 chr5:75003878 T/C cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6754311 0.861 rs12475139 chr2:136786651 A/T cg07169764 chr2:136633963 MCM6 0.56 8.49 0.42 6.57e-16 Mosquito bite size; LIHC cis rs6430585 0.528 rs115553816 chr2:136692893 G/A cg07169764 chr2:136633963 MCM6 1.29 21.41 0.76 4.13e-65 Corneal structure; LIHC cis rs56011263 0.687 rs4690292 chr4:703712 A/G cg14024328 chr4:719362 PCGF3 -0.46 -6.75 -0.34 6.49e-11 White blood cell count; LIHC cis rs3780378 0.967 rs7852988 chr9:5010751 C/A cg02405213 chr9:5042618 JAK2 -0.55 -9.85 -0.47 2.68e-20 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg12310025 chr6:25882481 NA -0.42 -6.47 -0.33 3.3e-10 Height; LIHC cis rs2070488 0.775 rs2186457 chr3:38553965 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.6 9.76 0.47 4.99e-20 Electrocardiographic conduction measures; LIHC cis rs1401999 1.000 rs10937158 chr3:183708439 T/C cg01324343 chr3:183735012 ABCC5 0.76 12.92 0.57 2.27e-31 Anterior chamber depth; LIHC cis rs3862260 0.509 rs1045827 chr1:120162442 C/T cg11530693 chr1:120165357 ZNF697 -0.49 -7.67 -0.38 1.77e-13 Systemic lupus erythematosus; LIHC cis rs9399135 0.967 rs6923827 chr6:135335382 C/T cg24558204 chr6:135376177 HBS1L 0.39 6.4 0.33 5.14e-10 Red blood cell count; LIHC cis rs6547741 0.844 rs9941696 chr2:27920064 C/T cg27432699 chr2:27873401 GPN1 -0.92 -16.31 -0.66 1.26e-44 Oral cavity cancer; LIHC cis rs8180040 0.620 rs6414435 chr3:47121140 A/G cg16586182 chr3:47516702 SCAP -0.49 -8.78 -0.43 7.8e-17 Colorectal cancer; LIHC cis rs6762 0.692 rs5030778 chr11:836008 T/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.69 -0.46 8.98e-20 Mean platelet volume; LIHC cis rs72627509 0.680 rs79641006 chr4:57847443 T/G cg16868167 chr4:57843880 C4orf14;POLR2B -0.64 -9.15 -0.44 5.41e-18 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs739401 0.611 rs494427 chr11:3048140 A/G cg05729581 chr11:3078854 CARS -0.43 -6.0 -0.31 5.11e-9 Longevity; LIHC cis rs1552244 0.572 rs113406084 chr3:10170190 T/C cg00149659 chr3:10157352 C3orf10 0.9 8.7 0.43 1.37e-16 Alzheimer's disease; LIHC cis rs3768617 0.565 rs2027080 chr1:183074415 C/T ch.1.3577855R chr1:183094577 LAMC1 0.62 10.79 0.5 1.46e-23 Fuchs's corneal dystrophy; LIHC trans rs79976124 0.842 rs74881738 chr6:66621825 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.82 0.35 4.19e-11 Type 2 diabetes; LIHC cis rs2204008 0.548 rs2320740 chr12:38166421 G/A cg26384229 chr12:38710491 ALG10B 0.82 10.25 0.48 1.14e-21 Bladder cancer; LIHC cis rs35306767 0.903 rs11813210 chr10:919796 G/A cg26597838 chr10:835615 NA 1.18 14.34 0.61 7.88e-37 Eosinophil percentage of granulocytes; LIHC cis rs2204008 0.774 rs10400552 chr12:38393577 C/G cg26384229 chr12:38710491 ALG10B 0.59 8.26 0.41 3.27e-15 Bladder cancer; LIHC trans rs4906332 1.000 rs78316803 chr14:103942863 A/G cg17675199 chr6:35436792 RPL10A 0.35 6.86 0.35 3.26e-11 Coronary artery disease; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.71 0.38 1.35e-13 Prudent dietary pattern; LIHC cis rs6952808 0.534 rs1113736 chr7:1992992 T/C cg04267008 chr7:1944627 MAD1L1 -0.63 -10.29 -0.49 7.97e-22 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs1932285 chr6:8477719 T/G cg21535247 chr6:8435926 SLC35B3 0.61 8.09 0.4 1.03e-14 Motion sickness; LIHC cis rs9534288 0.797 rs1134071 chr13:46562935 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.39e-15 Blood protein levels; LIHC trans rs208520 0.770 rs1342960 chr6:66883514 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.14 -0.4 7.54e-15 Exhaled nitric oxide output; LIHC cis rs2439831 0.867 rs8041132 chr15:43635136 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.87 0.67 6.92e-47 Lung cancer in ever smokers; LIHC cis rs9457247 0.765 rs3752520 chr6:167436159 T/C cg23791538 chr6:167370224 RNASET2 -0.52 -7.88 -0.39 4.34e-14 Crohn's disease; LIHC cis rs2073499 0.810 rs78501918 chr3:50369914 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.65 6.64 0.34 1.23e-10 Schizophrenia; LIHC cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg04025307 chr7:1156635 C7orf50 0.6 10.66 0.5 4.27e-23 Longevity;Endometriosis; LIHC cis rs8081395 0.627 rs180536 chr17:57996806 G/A cg13753209 chr17:57696993 CLTC 0.49 7.81 0.39 7.01e-14 White blood cell count; LIHC cis rs2153535 0.601 rs9505451 chr6:8469950 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs28595532 0.623 rs17516540 chr4:119278443 A/G cg21605333 chr4:119757512 SEC24D 0.84 6.89 0.35 2.75e-11 Cannabis dependence symptom count; LIHC cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs2204008 0.660 rs2320745 chr12:38239101 T/C cg26384229 chr12:38710491 ALG10B 0.83 10.62 0.5 5.97e-23 Bladder cancer; LIHC cis rs7520050 0.966 rs11211230 chr1:46406767 G/T cg03146154 chr1:46216737 IPP -0.39 -6.39 -0.33 5.52e-10 Red blood cell count;Reticulocyte count; LIHC cis rs11724804 0.532 rs62297079 chr4:879977 G/A cg20916646 chr4:852691 GAK 0.59 7.77 0.39 9.29e-14 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs1538970 0.961 rs7553318 chr1:45843086 A/G cg24296786 chr1:45957014 TESK2 -0.49 -7.2 -0.36 3.77e-12 Platelet count; LIHC cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15684811 chr1:59250924 JUN 0.45 6.05 0.31 3.73e-9 Lung function (FEV1/FVC); LIHC cis rs11958404 0.932 rs72818127 chr5:157452227 C/T cg05962755 chr5:157440814 NA 1.04 11.55 0.53 2.71e-26 IgG glycosylation; LIHC cis rs7131987 0.903 rs2216853 chr12:29413248 C/G cg12903224 chr12:29470962 FAR2 -0.37 -5.91 -0.3 8.31e-9 QT interval; LIHC cis rs6973256 0.637 rs1362739 chr7:133430934 C/A cg10665199 chr7:133106180 EXOC4 0.34 5.83 0.3 1.26e-8 Intelligence (multi-trait analysis); LIHC cis rs7537052 0.646 rs6680302 chr1:36653540 C/T cg24686825 chr1:36642396 MAP7D1 -0.44 -8.28 -0.41 2.86e-15 Schizophrenia; LIHC cis rs74417235 0.610 rs35212808 chr5:154057808 A/G cg19735590 chr5:154026979 NA 0.47 5.72 0.3 2.34e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC trans rs4332037 0.707 rs62435130 chr7:1890002 C/T cg11693508 chr17:37793320 STARD3 0.56 6.07 0.31 3.38e-9 Bipolar disorder; LIHC cis rs12478296 1.000 rs113129906 chr2:243004253 C/T cg05760424 chr2:242988095 NA -0.52 -7.06 -0.36 9.34e-12 Obesity-related traits; LIHC trans rs208520 0.874 rs208512 chr6:66943869 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -7.96 -0.4 2.5e-14 Exhaled nitric oxide output; LIHC cis rs6500602 0.627 rs860891 chr16:4586529 C/T cg08645402 chr16:4508243 NA -0.33 -5.74 -0.3 2.1e-8 Schizophrenia; LIHC cis rs847649 0.731 rs2298854 chr7:102729631 T/G cg18108683 chr7:102477205 FBXL13 0.41 6.02 0.31 4.62e-9 Morning vs. evening chronotype; LIHC cis rs4820539 1.000 rs916584 chr22:23469433 A/G cg21100191 chr22:23484243 RTDR1 0.9 16.52 0.67 1.72e-45 Bone mineral density; LIHC trans rs208520 0.779 rs208446 chr6:66903515 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.71 -7.65 -0.38 2.05e-13 Exhaled nitric oxide output; LIHC cis rs1982963 1.000 rs4901186 chr14:52509484 G/A cg10843707 chr14:52510701 NID2 -0.47 -8.59 -0.42 3.21e-16 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs35110281 0.641 rs9978858 chr21:45085552 A/G cg21573476 chr21:45109991 RRP1B -0.63 -11.29 -0.52 2.55e-25 Mean corpuscular volume; LIHC cis rs17685 0.753 rs7804598 chr7:75702578 C/T cg04610667 chr7:75704037 NA -0.33 -6.0 -0.31 5.08e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs4319547 0.915 rs7316734 chr12:123117425 A/G cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.18 -0.36 4.31e-12 Body mass index; LIHC cis rs8141529 0.636 rs5762813 chr22:29203314 C/T cg15103426 chr22:29168792 CCDC117 0.5 7.47 0.37 6.94e-13 Lymphocyte counts; LIHC cis rs4713118 0.662 rs149946 chr6:27970031 A/C cg16479474 chr6:28041457 NA -0.45 -6.78 -0.34 5.41e-11 Parkinson's disease; LIHC cis rs1843834 0.539 rs6739735 chr2:225405253 A/G cg22509189 chr2:225307070 NA 0.82 11.63 0.53 1.4e-26 IgE levels in asthmatics (D.p. specific); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04502814 chr5:42811952 SEPP1 0.33 6.85 0.35 3.37e-11 Cognitive function; LIHC cis rs1816752 0.837 rs9318530 chr13:24998557 A/G cg02811702 chr13:24901961 NA -0.25 -6.21 -0.32 1.58e-9 Obesity-related traits; LIHC cis rs2933343 0.951 rs9871612 chr3:128570402 C/T cg25356066 chr3:128598488 ACAD9 0.53 6.99 0.35 1.48e-11 IgG glycosylation; LIHC cis rs7927771 0.864 rs2293580 chr11:47440283 T/A cg20135002 chr11:47629003 NA 0.55 9.32 0.45 1.45e-18 Subjective well-being; LIHC cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg02290350 chr8:58132656 NA 0.49 8.77 0.43 8.6e-17 Developmental language disorder (linguistic errors); LIHC trans rs6489882 0.934 rs7299132 chr12:113376913 T/A cg10175203 chr3:128143634 NA 0.38 6.18 0.32 1.8e-9 Chronic lymphocytic leukemia; LIHC cis rs8077889 0.917 rs72836547 chr17:41902799 G/T cg26893861 chr17:41843967 DUSP3 0.99 10.76 0.5 1.9e-23 Triglycerides; LIHC cis rs1580019 0.563 rs764483 chr7:32578150 A/T cg06627557 chr7:32535165 LSM5;AVL9 1.12 25.06 0.8 2.07e-79 Cognitive ability; LIHC cis rs7614311 0.731 rs17401592 chr3:63954490 A/G cg22134162 chr3:63841271 THOC7 -0.54 -6.06 -0.31 3.61e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs12101261 1.000 rs12101255 chr14:81451052 C/T cg06600135 chr14:81408086 NA 0.36 6.17 0.32 1.93e-9 Graves' disease; LIHC cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg27170947 chr2:26402098 FAM59B -0.68 -8.4 -0.41 1.19e-15 Gut microbiome composition (summer); LIHC cis rs6912958 0.781 rs9444504 chr6:88181046 A/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.31 -6.01 -0.31 4.77e-9 Monocyte percentage of white cells; LIHC cis rs3815700 0.844 rs444089 chr19:33106991 G/C cg13320555 chr19:33072785 PDCD5 0.45 6.7 0.34 8.84e-11 Eosinophilic esophagitis; LIHC trans rs7246657 0.943 rs12709813 chr19:37844983 G/A cg24637308 chr11:6592297 DNHD1 0.43 6.09 0.31 2.99e-9 Coronary artery calcification; LIHC cis rs611744 0.647 rs1448151 chr8:109276283 C/A cg18478394 chr8:109455254 TTC35 0.43 7.44 0.37 8.07e-13 Dupuytren's disease; LIHC cis rs4700695 0.719 rs40176 chr5:65464965 C/T cg21114390 chr5:65439923 SFRS12 -0.59 -8.31 -0.41 2.27e-15 Facial morphology (factor 19); LIHC cis rs7927592 0.956 rs10896334 chr11:68281494 C/T cg16797656 chr11:68205561 LRP5 0.53 8.39 0.41 1.31e-15 Total body bone mineral density; LIHC cis rs7208859 0.573 rs55661352 chr17:29045628 A/G cg13385521 chr17:29058706 SUZ12P 0.84 8.3 0.41 2.53e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1008375 1.000 rs56974987 chr4:17627856 G/A cg16339924 chr4:17578868 LAP3 0.43 6.07 0.31 3.31e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09331995 chr7:27309021 NA 0.42 6.94 0.35 1.99e-11 Longevity; LIHC cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg24209194 chr3:40518798 ZNF619 -0.5 -7.49 -0.38 5.91e-13 Renal cell carcinoma; LIHC cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg07424592 chr7:64974309 NA -0.8 -9.08 -0.44 8.8e-18 Diabetic kidney disease; LIHC cis rs10876993 0.928 rs2640629 chr12:58065448 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.06 -0.31 3.5e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg12516959 chr21:47718080 NA -0.36 -5.87 -0.3 1.05e-8 Testicular germ cell tumor; LIHC cis rs3820068 0.603 rs72647118 chr1:15956535 G/T cg17385448 chr1:15911702 AGMAT 0.34 5.93 0.31 7.31e-9 Systolic blood pressure; LIHC cis rs4819052 0.851 rs9974891 chr21:46680767 T/A cg11663144 chr21:46675770 NA -0.3 -5.75 -0.3 1.94e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs311392 0.554 rs377049 chr8:55097512 A/G cg20636351 chr8:55087400 NA -0.36 -7.31 -0.37 1.87e-12 Pelvic organ prolapse (moderate/severe); LIHC cis rs4332037 0.552 rs11773627 chr7:2002733 A/G cg23422044 chr7:1970798 MAD1L1 -0.62 -7.1 -0.36 7.16e-12 Bipolar disorder; LIHC cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg05665937 chr4:1216051 CTBP1 0.39 6.2 0.32 1.64e-9 Obesity-related traits; LIHC cis rs2279817 0.863 rs13375585 chr1:18016657 G/A cg21791023 chr1:18019539 ARHGEF10L -0.68 -7.99 -0.4 2.06e-14 Neuroticism; LIHC cis rs9916302 0.904 rs600010 chr17:37433517 T/C cg07936489 chr17:37558343 FBXL20 -0.82 -13.17 -0.58 2.5e-32 Glomerular filtration rate (creatinine); LIHC cis rs1580019 0.885 rs4460269 chr7:32496445 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs2361710 0.669 rs12940486 chr17:78118569 T/C cg09238746 chr17:78121135 EIF4A3 -0.54 -8.29 -0.41 2.59e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; LIHC cis rs11671005 0.651 rs55716128 chr19:59048754 C/T cg25952890 chr19:58913133 NA 0.67 6.72 0.34 7.43e-11 Mean platelet volume; LIHC cis rs7927592 0.913 rs7115374 chr11:68300076 G/T cg16797656 chr11:68205561 LRP5 0.51 8.1 0.4 9.54e-15 Total body bone mineral density; LIHC cis rs11931598 0.511 rs35772786 chr4:7021211 T/G cg19539972 chr4:7069911 GRPEL1 0.41 6.45 0.33 3.75e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs1185460 0.547 rs667584 chr11:118911544 C/T cg01677386 chr11:118938358 VPS11 0.44 5.89 0.3 9.22e-9 Coronary artery disease; LIHC trans rs617791 0.508 rs2276132 chr11:65770545 G/A cg17712092 chr4:129076599 LARP1B -0.56 -6.81 -0.35 4.49e-11 Breast cancer; LIHC cis rs8064024 0.538 rs11076854 chr16:4929269 A/G cg08329684 chr16:4932620 PPL -0.42 -7.43 -0.37 8.71e-13 Cancer; LIHC cis rs7647973 0.593 rs4855885 chr3:49690199 G/A cg03060546 chr3:49711283 APEH 0.54 5.92 0.3 7.73e-9 Menarche (age at onset); LIHC cis rs9916302 0.706 rs8069074 chr17:37685401 C/T cg00129232 chr17:37814104 STARD3 0.4 5.71 0.3 2.46e-8 Glomerular filtration rate (creatinine); LIHC cis rs2075671 0.903 rs11983334 chr7:100302434 C/T cg20848291 chr7:100343083 ZAN -0.47 -6.77 -0.34 5.52e-11 Other erythrocyte phenotypes; LIHC cis rs1577917 0.560 rs12193777 chr6:86246709 C/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.37 6.57 0.33 1.89e-10 Response to antipsychotic treatment; LIHC cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg21448741 chr8:58168803 NA -0.33 -5.76 -0.3 1.87e-8 Developmental language disorder (linguistic errors); LIHC cis rs9296092 0.538 rs9469486 chr6:33516849 G/A cg13560919 chr6:33536144 NA -0.38 -6.36 -0.33 6.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.4 0.49 3.47e-22 Colorectal cancer; LIHC cis rs45544231 0.544 rs9926163 chr16:52565641 G/T cg09051775 chr16:52580266 TOX3 -0.32 -5.88 -0.3 9.89e-9 Restless legs syndrome; LIHC cis rs763121 0.962 rs138711 chr22:39139913 C/T cg06022373 chr22:39101656 GTPBP1 0.55 8.25 0.41 3.41e-15 Menopause (age at onset); LIHC cis rs2153535 0.580 rs1932279 chr6:8473653 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs2073300 0.609 rs6132605 chr20:23354839 A/C cg12062639 chr20:23401060 NAPB 1.08 14.3 0.61 1.05e-36 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1865760 0.516 rs9358903 chr6:26061949 A/C cg18357526 chr6:26021779 HIST1H4A 0.49 7.18 0.36 4.37e-12 Height; LIHC cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC cis rs1552244 0.816 rs56387520 chr3:10042782 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.7 9.53 0.46 2.93e-19 Alzheimer's disease; LIHC cis rs12824058 0.831 rs11609362 chr12:130810526 T/C cg26677194 chr12:130822605 PIWIL1 0.52 7.36 0.37 1.36e-12 Menopause (age at onset); LIHC cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg13409248 chr3:40428643 ENTPD3 0.42 7.05 0.36 1e-11 Renal cell carcinoma; LIHC trans rs1814175 0.935 rs11040465 chr11:49689323 C/T cg03929089 chr4:120376271 NA -0.9 -17.51 -0.69 1.87e-49 Height; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00529697 chr5:75013131 C5orf37 0.44 6.74 0.34 6.83e-11 Calcium levels; LIHC cis rs2439831 0.681 rs1095386 chr15:43609509 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.9 17.09 0.68 8.61e-48 Lung cancer in ever smokers; LIHC cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg00684032 chr4:1343700 KIAA1530 0.51 7.35 0.37 1.5e-12 Obesity-related traits; LIHC cis rs7927771 0.965 rs17788930 chr11:47752775 A/G cg20307385 chr11:47447363 PSMC3 -0.44 -5.82 -0.3 1.33e-8 Subjective well-being; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg10590909 chr10:70286987 SLC25A16 -0.44 -6.53 -0.33 2.41e-10 Triglycerides; LIHC cis rs6835098 0.816 rs13111572 chr4:174159788 G/A cg27433088 chr4:174089019 GALNT7 -0.37 -5.97 -0.31 6.02e-9 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs8072100 0.934 rs8067286 chr17:45594590 A/G cg08085267 chr17:45401833 C17orf57 0.56 8.39 0.41 1.3e-15 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs11190604 1.000 rs10786596 chr10:102282126 C/A cg07080220 chr10:102295463 HIF1AN 0.56 8.2 0.41 4.94e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs981946 0.570 rs6923667 chr6:3359194 C/T cg18842474 chr6:3356384 SLC22A23 0.39 6.34 0.32 7.36e-10 Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN); LIHC cis rs28493229 1.000 rs28493229 chr19:41224204 G/C cg21869046 chr19:41225005 ITPKC 0.5 6.21 0.32 1.55e-9 Kawasaki disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10053149 chr1:28908509 SNHG12;SNORA44;SNORA16A -0.46 -6.69 -0.34 9.17e-11 Cognitive function; LIHC cis rs796364 1.000 rs281762 chr2:200799201 C/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.69 8.27 0.41 2.94e-15 Schizophrenia; LIHC cis rs7615952 0.932 rs7630077 chr3:125649676 T/C cg05084668 chr3:125655381 ALG1L -0.57 -8.18 -0.4 5.49e-15 Blood pressure (smoking interaction); LIHC cis rs7647973 0.626 rs7649428 chr3:49868876 A/T cg03060546 chr3:49711283 APEH -0.62 -7.11 -0.36 7.03e-12 Menarche (age at onset); LIHC cis rs9303401 0.659 rs34170300 chr17:56789905 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.02 0.54 5.49e-28 Cognitive test performance; LIHC cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg05890377 chr2:74357713 NA -0.6 -11.95 -0.54 9.74e-28 Gestational age at birth (maternal effect); LIHC cis rs9467773 1.000 rs12526680 chr6:26550954 A/G cg11502198 chr6:26597334 ABT1 0.46 6.97 0.35 1.66e-11 Intelligence (multi-trait analysis); LIHC cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg03354898 chr7:1950403 MAD1L1 -0.36 -5.74 -0.3 2.1e-8 Bipolar disorder and schizophrenia; LIHC cis rs34172651 0.917 rs7204281 chr16:24784475 C/T cg04756594 chr16:24857601 SLC5A11 0.44 6.99 0.35 1.45e-11 Intelligence (multi-trait analysis); LIHC cis rs6570726 0.791 rs2096201 chr6:145934273 C/T cg13319975 chr6:146136371 FBXO30 -0.43 -6.8 -0.34 4.77e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg02359409 chr6:42947317 PEX6 -0.47 -6.66 -0.34 1.07e-10 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs9929218 0.559 rs12923775 chr16:68756450 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.83 17.65 0.69 5.06e-50 Colorectal cancer; LIHC cis rs4073582 0.576 rs556595 chr11:66058082 T/G cg16950941 chr11:66035639 RAB1B 0.54 8.16 0.4 6.47e-15 Gout; LIHC cis rs2549003 1.000 rs13170412 chr5:131823519 A/G cg02551604 chr5:131831745 NA -0.49 -7.2 -0.36 3.75e-12 Asthma (sex interaction); LIHC cis rs17152411 1.000 rs7092008 chr10:126638226 G/A cg07906193 chr10:126599966 NA 0.49 7.74 0.39 1.16e-13 Height; LIHC cis rs57590327 0.679 rs34674953 chr3:81605113 T/G cg07356753 chr3:81810745 GBE1 -0.47 -6.48 -0.33 3.21e-10 Extraversion; LIHC cis rs2607426 0.681 rs74628863 chr19:41291872 G/A cg20631044 chr19:41255890 C19orf54;SNRPA -0.54 -5.98 -0.31 5.51e-9 Blood protein levels; LIHC cis rs9790314 0.582 rs6796201 chr3:160634313 A/G cg03342759 chr3:160939853 NMD3 0.56 7.44 0.37 8.32e-13 Morning vs. evening chronotype; LIHC cis rs11122272 0.668 rs1538664 chr1:231555295 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -10.42 -0.49 2.83e-22 Hemoglobin concentration; LIHC cis rs644799 1.000 rs473148 chr11:95628606 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.65 8.89 0.43 3.67e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7187994 0.848 rs12443928 chr16:84780202 G/T cg07647771 chr16:84786436 USP10 -0.34 -5.98 -0.31 5.63e-9 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs7953508 0.506 rs2053196 chr12:93962959 T/C cg18151635 chr12:93972918 NA -0.5 -8.38 -0.41 1.43e-15 Pubertal anthropometrics; LIHC cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg22633049 chr21:46681294 NA -0.37 -6.37 -0.33 5.94e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3857067 0.776 rs6858265 chr4:95112565 A/G cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.52 -0.38 4.86e-13 QT interval; LIHC cis rs5770917 1.000 rs762677 chr22:51017713 G/A cg05156901 chr22:51016646 CPT1B;CHKB-CPT1B -0.46 -6.74 -0.34 6.8e-11 Narcolepsy; LIHC cis rs16828019 0.852 rs12759050 chr1:41664204 T/A cg20697417 chr1:41786797 NA 0.35 6.59 0.34 1.66e-10 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC cis rs9640161 0.789 rs28439010 chr7:150046276 C/T cg17279839 chr7:150038598 RARRES2 0.58 12.11 0.55 2.54e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.56 -0.33 2e-10 Bipolar disorder and schizophrenia; LIHC trans rs4843747 0.605 rs4072779 chr16:88107290 C/T cg09572067 chr16:29127029 RRN3P2 0.49 7.81 0.39 7.29e-14 Menopause (age at onset); LIHC cis rs908922 0.676 rs4240883 chr1:152526260 C/T cg20991723 chr1:152506922 NA 0.57 9.99 0.48 8.72e-21 Hair morphology; LIHC cis rs600806 0.672 rs1144593 chr1:110030945 A/G cg08911820 chr1:110026001 ATXN7L2 0.57 6.87 0.35 3.07e-11 Intelligence (multi-trait analysis); LIHC cis rs2303745 0.589 rs6512182 chr19:17399476 G/T cg04248312 chr19:17393744 ANKLE1 -0.73 -12.07 -0.55 3.51e-28 Systemic lupus erythematosus; LIHC cis rs4819052 0.655 rs2330102 chr21:46690968 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.66 0.38 1.9e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2274273 0.805 rs7159808 chr14:55624327 G/T cg04306507 chr14:55594613 LGALS3 0.32 6.18 0.32 1.82e-9 Protein biomarker; LIHC cis rs10911363 0.592 rs4047798 chr1:183421406 C/T cg09173681 chr1:183549694 NCF2 -0.56 -9.76 -0.47 5.3e-20 Systemic lupus erythematosus; LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs11758351 0.660 rs2143345 chr6:26229148 C/T cg16070018 chr6:26224392 HIST1H3E 0.56 6.89 0.35 2.63e-11 Gout;Renal underexcretion gout; LIHC cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg17971929 chr21:40555470 PSMG1 0.81 9.67 0.46 1.06e-19 Cognitive function; LIHC cis rs6500602 0.927 rs7200817 chr16:4480598 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.63 0.34 1.29e-10 Schizophrenia; LIHC cis rs611744 0.967 rs650968 chr8:109211055 C/G cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs763121 0.819 rs5757126 chr22:38923675 T/C cg14440974 chr22:39074834 NA -0.44 -6.83 -0.35 3.87e-11 Menopause (age at onset); LIHC trans rs72960926 0.744 rs55784940 chr6:74923315 G/T cg07247405 chr1:2484626 LOC115110 0.56 6.62 0.34 1.36e-10 Metabolite levels (MHPG); LIHC cis rs2806561 0.734 rs2806564 chr1:23506685 T/C cg12483005 chr1:23474871 LUZP1 0.46 7.31 0.37 1.95e-12 Height; LIHC cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg13271783 chr10:134563150 INPP5A -0.6 -7.17 -0.36 4.74e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17125944 0.505 rs75296244 chr14:53233218 G/A cg00686598 chr14:53173677 PSMC6 1.29 15.75 0.65 2.06e-42 Alzheimer's disease (late onset); LIHC cis rs3806843 1.000 rs6891995 chr5:140172008 A/G cg19875535 chr5:140030758 IK 0.36 5.9 0.3 8.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs12477438 0.700 rs10190421 chr2:99670711 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.53 -0.49 1.24e-22 Chronic sinus infection; LIHC cis rs7552404 1.000 rs7513559 chr1:76173744 A/G cg10523679 chr1:76189770 ACADM 0.64 8.7 0.43 1.43e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7149242 0.961 rs7142683 chr14:101158882 A/G cg11726507 chr14:101155519 NA -0.27 -6.06 -0.31 3.5e-9 Platelet count; LIHC cis rs9649465 1.000 rs7776792 chr7:123335350 C/T cg03229431 chr7:123269106 ASB15 0.39 8.29 0.41 2.7e-15 Migraine; LIHC cis rs17125944 0.505 rs17125762 chr14:53289288 A/G cg13660082 chr14:53194042 PSMC6 -0.42 -6.59 -0.34 1.64e-10 Alzheimer's disease (late onset); LIHC cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg05368731 chr17:41323189 NBR1 0.73 12.62 0.56 2.97e-30 Menopause (age at onset); LIHC cis rs34779708 0.966 rs12765038 chr10:35416513 G/C cg03585969 chr10:35415529 CREM 0.87 13.18 0.58 2.31e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4690686 0.769 rs11133146 chr4:177278878 C/T cg17059388 chr4:177262070 NA -0.37 -6.84 -0.35 3.59e-11 Essential tremor; LIHC cis rs7412746 0.611 rs16827671 chr1:150738759 T/C cg17724175 chr1:150552817 MCL1 0.46 9.16 0.44 4.94e-18 Melanoma; LIHC cis rs7961581 0.700 rs1510940 chr12:71645945 T/A cg05756094 chr12:71608604 NA 0.38 6.11 0.31 2.78e-9 Type 2 diabetes; LIHC cis rs2839186 0.967 rs17176131 chr21:47705237 T/C cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.41e-8 Testicular germ cell tumor; LIHC trans rs75804782 0.521 rs72993056 chr2:239404671 G/T cg01134436 chr17:81009848 B3GNTL1 0.83 6.94 0.35 1.94e-11 Morning vs. evening chronotype;Chronotype; LIHC cis rs1153858 0.887 rs28569043 chr15:45730926 A/T cg26924012 chr15:45694286 SPATA5L1 0.75 13.68 0.59 2.89e-34 Homoarginine levels; LIHC cis rs6502050 0.769 rs8068708 chr17:80120424 T/C cg11859384 chr17:80120422 CCDC57 -0.42 -5.73 -0.3 2.25e-8 Life satisfaction; LIHC cis rs2243480 1.000 rs3885839 chr7:65290403 G/T cg05590025 chr7:65112418 INTS4L2 -0.6 -6.45 -0.33 3.93e-10 Diabetic kidney disease; LIHC cis rs34779708 0.931 rs4934535 chr10:35432721 G/T cg03585969 chr10:35415529 CREM 0.87 13.17 0.58 2.45e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11761441 1.000 rs11761441 chr7:82377 G/A cg25149888 chr7:81075 NA 0.3 7.07 0.36 8.75e-12 Alzheimer's disease in APOE e4- carriers; LIHC cis rs910316 0.712 rs10131894 chr14:75446879 C/G cg08847533 chr14:75593920 NEK9 0.88 17.8 0.69 1.22e-50 Height; LIHC cis rs11190604 1.000 rs10883506 chr10:102289743 C/G cg07080220 chr10:102295463 HIF1AN 0.57 8.08 0.4 1.15e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7666738 0.606 rs28625338 chr4:99076996 A/G cg05340658 chr4:99064831 C4orf37 0.65 11.66 0.53 1.08e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2842992 0.915 rs1322427 chr6:160075454 C/A cg11366901 chr6:160182831 ACAT2 0.95 15.06 0.63 1.1e-39 Age-related macular degeneration (geographic atrophy); LIHC cis rs9457247 0.508 rs6941355 chr6:167506238 A/G cg12798992 chr6:167411361 FGFR1OP 0.42 6.71 0.34 7.89e-11 Crohn's disease; LIHC cis rs477895 1.000 rs2286614 chr11:64068310 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 7.98 0.4 2.22e-14 Mean platelet volume; LIHC cis rs3741404 0.791 rs2282491 chr11:63918373 T/C cg24431193 chr11:63883947 FLRT1;MACROD1 -0.38 -5.89 -0.3 9.46e-9 Platelet count; LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg07167872 chr1:205819463 PM20D1 0.72 10.73 0.5 2.36e-23 Menarche (age at onset); LIHC cis rs7106204 0.686 rs16912345 chr11:24283119 A/G ch.11.24196551F chr11:24239977 NA 0.64 5.83 0.3 1.28e-8 Response to Homoharringtonine (cytotoxicity); LIHC cis rs801193 0.805 rs12532355 chr7:66070584 C/G cg18876405 chr7:65276391 NA -0.41 -7.34 -0.37 1.58e-12 Aortic root size; LIHC cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg22105103 chr4:187893119 NA 0.34 8.3 0.41 2.4e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs6704768 0.545 rs5004510 chr2:233679275 A/C cg08000102 chr2:233561755 GIGYF2 -0.77 -9.3 -0.45 1.68e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg20607798 chr8:58055168 NA 0.62 7.91 0.39 3.52e-14 Developmental language disorder (linguistic errors); LIHC cis rs2404602 0.684 rs11854850 chr15:76844571 C/T cg03037974 chr15:76606532 NA -0.61 -10.19 -0.48 1.75e-21 Blood metabolite levels; LIHC cis rs9325144 0.555 rs7968322 chr12:38792348 T/C cg26384229 chr12:38710491 ALG10B -0.56 -7.58 -0.38 3.24e-13 Morning vs. evening chronotype; LIHC trans rs916888 0.610 rs199452 chr17:44801340 C/T cg22968622 chr17:43663579 NA 0.48 7.1 0.36 7.32e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg25072359 chr17:41440525 NA 0.37 5.88 0.3 9.95e-9 Menopause (age at onset); LIHC cis rs2637266 1.000 rs12251568 chr10:78345667 C/T cg18941641 chr10:78392320 NA 0.29 6.22 0.32 1.43e-9 Pulmonary function; LIHC cis rs7772486 0.790 rs9403749 chr6:146162239 A/G cg05347473 chr6:146136440 FBXO30 0.4 6.45 0.33 3.9e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs17102423 0.755 rs884683 chr14:65574482 C/T cg11161011 chr14:65562177 MAX -0.59 -8.24 -0.41 3.65e-15 Obesity-related traits; LIHC cis rs79839061 0.610 rs2279182 chr4:882625 T/G cg12601576 chr4:906860 GAK -0.61 -5.73 -0.3 2.22e-8 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs9897425 chr17:41430179 C/G cg23758822 chr17:41437982 NA 0.92 16.9 0.67 5.43e-47 Menopause (age at onset); LIHC cis rs12478296 0.792 rs57482298 chr2:243011148 C/A cg18898632 chr2:242989856 NA -0.69 -8.68 -0.42 1.64e-16 Obesity-related traits; LIHC cis rs713477 0.967 rs8009706 chr14:55914756 A/G cg13175173 chr14:55914753 NA -0.36 -8.58 -0.42 3.45e-16 Pediatric bone mineral content (femoral neck); LIHC cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.52 8.23 0.41 3.91e-15 Schizophrenia; LIHC cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg10802521 chr3:52805072 NEK4 -0.44 -7.61 -0.38 2.72e-13 Bipolar disorder; LIHC cis rs7927592 0.913 rs7107622 chr11:68374183 T/C cg01657329 chr11:68192670 LRP5 -0.48 -6.34 -0.32 7.26e-10 Total body bone mineral density; LIHC cis rs4891159 0.756 rs55763305 chr18:74161249 G/C cg24786174 chr18:74118243 ZNF516 -0.69 -12.27 -0.55 6.5e-29 Longevity; LIHC cis rs6500602 0.964 rs2304633 chr16:4496973 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.45 6.89 0.35 2.77e-11 Schizophrenia; LIHC cis rs8062405 1.000 rs12446589 chr16:28870962 G/A cg00204512 chr16:28754710 NA 0.36 6.44 0.33 3.94e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg26338869 chr17:61819248 STRADA 0.6 8.84 0.43 4.97e-17 Prudent dietary pattern; LIHC cis rs1568889 1.000 rs12803655 chr11:28060785 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.81 0.35 4.36e-11 Bipolar disorder; LIHC cis rs826838 0.935 rs1486357 chr12:39073675 A/G cg26384229 chr12:38710491 ALG10B 0.9 11.93 0.54 1.14e-27 Heart rate; LIHC cis rs875971 0.545 rs6460298 chr7:65907770 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.35 7.02 0.35 1.21e-11 Aortic root size; LIHC cis rs7208859 0.623 rs11652631 chr17:29060766 A/G cg13385521 chr17:29058706 SUZ12P 0.84 8.37 0.41 1.49e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1355223 0.583 rs2941058 chr11:34880245 C/G cg11058730 chr11:34937778 PDHX;APIP 0.75 13.73 0.6 1.74e-34 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2404602 0.692 rs4442773 chr15:77031633 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.92 0.3 8.02e-9 Blood metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02307161 chr20:16710695 SNRPB2 0.45 6.16 0.32 2.07e-9 Pancreatic cancer; LIHC cis rs17685 0.712 rs4732578 chr7:75721532 A/G cg01364799 chr7:75623366 TMEM120A -0.5 -7.41 -0.37 9.97e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9303280 0.901 rs2305479 chr17:38062217 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.25 0.36 2.84e-12 Self-reported allergy; LIHC cis rs4332037 0.722 rs4719332 chr7:1914681 G/A cg23422044 chr7:1970798 MAD1L1 -0.69 -10.6 -0.5 6.77e-23 Bipolar disorder; LIHC trans rs4797559 0.839 rs4797560 chr18:11583495 C/T cg07050032 chr17:78009173 CCDC40;TBC1D16 0.42 6.19 0.32 1.77e-9 Exploratory eye movement dysfunction in schizophrenia (total eye scanning length); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg01824349 chr5:98260405 CHD1 -0.28 -6.21 -0.32 1.56e-9 Calcium levels; LIHC cis rs10193935 0.901 rs6544533 chr2:42516372 G/C cg27598129 chr2:42591480 NA -0.68 -10.58 -0.5 7.85e-23 Colonoscopy-negative controls vs population controls; LIHC cis rs10256972 0.524 rs6945202 chr7:1116558 T/C cg07308232 chr7:1071921 C7orf50 -0.44 -6.78 -0.34 5.31e-11 Longevity;Endometriosis; LIHC cis rs9858542 0.953 rs3811699 chr3:49396360 T/C cg03060546 chr3:49711283 APEH -0.46 -6.32 -0.32 8.16e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4253772 0.744 rs1134224 chr22:46633371 A/T cg24881330 chr22:46731750 TRMU 0.57 6.04 0.31 4.04e-9 LDL cholesterol;Cholesterol, total; LIHC cis rs2304069 0.826 rs2244195 chr5:149403528 C/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.95 12.22 0.55 9.31e-29 HIV-1 control; LIHC cis rs483180 0.511 rs496198 chr1:120207177 A/G cg19096424 chr1:120255104 PHGDH -0.59 -7.4 -0.37 1.07e-12 Macular telangiectasia type 2; LIHC cis rs909341 0.909 rs1758205 chr20:62355756 G/A cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.74e-11 Atopic dermatitis; LIHC cis rs801193 0.591 rs2707839 chr7:66193084 A/G cg11764359 chr7:65958608 NA 0.83 14.75 0.62 1.92e-38 Aortic root size; LIHC cis rs7188697 0.882 rs9921370 chr16:58611935 C/A cg02549819 chr16:58548995 SETD6 0.48 7.57 0.38 3.46e-13 QT interval; LIHC cis rs9303401 0.659 rs34556735 chr17:56694447 A/C cg25039879 chr17:56429692 SUPT4H1 0.86 9.68 0.46 9.63e-20 Cognitive test performance; LIHC cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg00149659 chr3:10157352 C3orf10 0.66 6.81 0.35 4.32e-11 Alzheimer's disease; LIHC cis rs6762 0.719 rs7936806 chr11:839186 G/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.78 -9.62 -0.46 1.51e-19 Mean platelet volume; LIHC cis rs4141404 0.787 rs4820042 chr22:31589056 T/C cg22777020 chr22:31556080 RNF185 -0.55 -6.26 -0.32 1.15e-9 Paclitaxel-induced neuropathy; LIHC cis rs2204008 0.837 rs11168387 chr12:37962818 G/A cg26384229 chr12:38710491 ALG10B -0.47 -6.63 -0.34 1.3100000000000001e-10 Bladder cancer; LIHC cis rs1005277 0.579 rs176886 chr10:38403974 C/T cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs6952808 0.792 rs11771973 chr7:1950440 C/G cg21782813 chr7:2030301 MAD1L1 0.48 7.98 0.4 2.24e-14 Bipolar disorder and schizophrenia; LIHC cis rs11761441 1.000 rs11761441 chr7:82377 G/A cg13828236 chr7:80970 NA 0.29 7.06 0.36 9.49e-12 Alzheimer's disease in APOE e4- carriers; LIHC cis rs55702914 0.839 rs2059922 chr2:198188903 C/G cg03934865 chr2:198174659 NA -0.41 -5.76 -0.3 1.89e-8 Major depression and alcohol dependence; LIHC cis rs763121 0.853 rs2267394 chr22:39101633 T/C cg06022373 chr22:39101656 GTPBP1 0.74 14.71 0.62 2.82e-38 Menopause (age at onset); LIHC trans rs11098499 0.863 rs1552092 chr4:120488496 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.46 0.46 5.19e-19 Corneal astigmatism; LIHC cis rs2404602 0.692 rs35557205 chr15:77130711 T/G cg03037974 chr15:76606532 NA 0.73 14.06 0.61 9.63e-36 Blood metabolite levels; LIHC cis rs7927592 0.913 rs10896330 chr11:68254998 A/G cg20283391 chr11:68216788 NA -0.51 -7.62 -0.38 2.57e-13 Total body bone mineral density; LIHC cis rs6424115 0.830 rs2503000 chr1:24197898 C/G cg04160030 chr1:24195659 FUCA1 -0.36 -5.88 -0.3 9.82e-9 Immature fraction of reticulocytes; LIHC cis rs9393692 0.905 rs6931391 chr6:26279235 G/C cg13736514 chr6:26305472 NA -0.38 -6.39 -0.33 5.41e-10 Educational attainment; LIHC trans rs1814175 0.617 rs6486020 chr11:49769149 T/G cg03929089 chr4:120376271 NA -0.83 -15.82 -0.65 1.04e-42 Height; LIHC cis rs7572733 0.576 rs1865586 chr2:198758868 C/T cg00792783 chr2:198669748 PLCL1 -0.46 -6.68 -0.34 9.93e-11 Dermatomyositis; LIHC cis rs9556958 0.708 rs4772092 chr13:99166614 A/G cg07423050 chr13:99094983 FARP1 -0.34 -5.88 -0.3 9.96e-9 Educational attainment (years of education); LIHC cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg00612595 chr21:47717864 NA 0.35 5.91 0.3 8.19e-9 Testicular germ cell tumor; LIHC cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg06634786 chr22:41940651 POLR3H -0.82 -8.99 -0.44 1.75e-17 Vitiligo; LIHC cis rs4727027 0.866 rs10435245 chr7:148816081 C/G cg23583168 chr7:148888333 NA -0.69 -9.76 -0.47 4.98e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs11098499 0.818 rs55825515 chr4:120486402 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.42 0.45 6.82e-19 Corneal astigmatism; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg07677032 chr17:61819896 STRADA 0.42 6.07 0.31 3.34e-9 Prudent dietary pattern; LIHC cis rs425535 0.588 rs4694657 chr4:74822074 T/A cg02530824 chr4:74847766 PF4 -0.37 -5.95 -0.31 6.57e-9 Blood protein levels; LIHC cis rs4684776 1.000 rs4684774 chr3:11426086 T/C cg00170343 chr3:11313890 ATG7 -0.43 -5.83 -0.3 1.25e-8 Small vessel stroke; LIHC cis rs6060717 0.654 rs6060686 chr20:34512606 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -9.84 -0.47 2.81e-20 Hip circumference adjusted for BMI; LIHC cis rs7917772 0.503 rs2031601 chr10:104308064 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.59 0.56 3.86e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs60871478 0.592 rs4275123 chr7:857352 A/G cg05535760 chr7:792225 HEATR2 -0.59 -6.81 -0.35 4.31e-11 Cerebrospinal P-tau181p levels; LIHC cis rs2380220 0.810 rs66524640 chr6:95956566 T/C cg15832292 chr6:96025679 MANEA -0.6 -6.65 -0.34 1.16e-10 Behavioural disinhibition (generation interaction); LIHC cis rs9368481 0.569 rs6907403 chr6:26877297 A/C cg18867708 chr6:26865862 GUSBL1 0.55 8.3 0.41 2.37e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -10.72 -0.5 2.56e-23 Platelet count; LIHC cis rs4900538 0.963 rs8017980 chr14:102961341 C/G cg18135206 chr14:102964638 TECPR2 0.95 15.93 0.65 4.09e-43 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs7131987 0.868 rs10771508 chr12:29414211 G/A cg16970926 chr12:29381810 FAR2 0.32 6.8 0.34 4.75e-11 QT interval; LIHC cis rs1728785 0.892 rs1170427 chr16:68603852 G/T cg02972257 chr16:68554789 NA -0.54 -6.19 -0.32 1.69e-9 Ulcerative colitis; LIHC cis rs7647973 0.626 rs9835157 chr3:49797769 G/A cg03060546 chr3:49711283 APEH -0.6 -6.85 -0.35 3.53e-11 Menarche (age at onset); LIHC cis rs3768617 0.510 rs2093985 chr1:183094322 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.49 0.49 1.67e-22 Fuchs's corneal dystrophy; LIHC cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg22764044 chr5:178986830 RUFY1 0.39 5.79 0.3 1.62e-8 Lung cancer; LIHC cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg10802521 chr3:52805072 NEK4 -0.44 -7.48 -0.38 6.22e-13 Bipolar disorder; LIHC cis rs9814567 0.964 rs9820150 chr3:134223011 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.06 -0.31 3.65e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7119038 0.818 rs2155433 chr11:118612921 G/A cg19308663 chr11:118741387 NA 0.4 6.3 0.32 9.07e-10 Sjögren's syndrome; LIHC cis rs2576037 0.583 rs1465722 chr18:44564499 C/G cg19077165 chr18:44547161 KATNAL2 0.49 7.35 0.37 1.44e-12 Personality dimensions; LIHC cis rs10876993 0.821 rs1629032 chr12:58038686 C/T cg18357645 chr12:58087776 OS9 0.49 8.09 0.4 1.06e-14 Celiac disease or Rheumatoid arthritis; LIHC cis rs743757 1.000 rs2236964 chr3:50449062 C/G cg08207895 chr3:50388901 TUSC4;CYB561D2 -0.48 -7.43 -0.37 8.55e-13 Diastolic blood pressure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg07667813 chr19:7985168 SNAPC2 -0.49 -6.46 -0.33 3.7e-10 Pancreatic cancer; LIHC cis rs11764590 0.715 rs9639202 chr7:2087315 G/A cg23422044 chr7:1970798 MAD1L1 -0.5 -5.81 -0.3 1.43e-8 Neuroticism; LIHC cis rs4803468 1.000 rs878082 chr19:41897674 G/A cg14132834 chr19:41945861 ATP5SL -0.41 -6.06 -0.31 3.62e-9 Height; LIHC cis rs7520050 0.778 rs3014216 chr1:46035760 A/T cg24296786 chr1:45957014 TESK2 -0.42 -6.16 -0.32 2.05e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7267979 0.565 rs958075 chr20:25595123 C/T cg24626310 chr20:25276739 ABHD12;PYGB -0.42 -5.93 -0.31 7.52e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs35883536 0.647 rs2647325 chr1:101040195 T/C cg14515779 chr1:101123966 NA -0.45 -6.38 -0.33 5.67e-10 Monocyte count; LIHC cis rs11628318 0.614 rs7155883 chr14:103123404 A/C cg23461800 chr14:103021989 NA 0.42 5.89 0.3 9.47e-9 Platelet count; LIHC cis rs6701037 0.555 rs10912899 chr1:175120715 C/T cg00321850 chr1:175162397 KIAA0040 0.34 6.05 0.31 3.85e-9 Alcohol dependence; LIHC cis rs78545713 1.000 rs11753610 chr6:26251601 C/T cg16070018 chr6:26224392 HIST1H3E -0.72 -7.46 -0.37 7.27e-13 Iron status biomarkers (total iron binding capacity); LIHC cis rs2153535 0.580 rs1414348 chr6:8471940 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.99 0.4 2.11e-14 Motion sickness; LIHC cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg03452623 chr4:187889614 NA -0.32 -8.36 -0.41 1.55e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs2115630 1.000 rs55646601 chr15:85323568 G/T cg12501888 chr15:85177176 SCAND2 -0.5 -7.83 -0.39 6.08e-14 P wave terminal force; LIHC cis rs10751667 0.961 rs6597951 chr11:991530 C/T ch.11.42038R chr11:967971 AP2A2 0.59 10.92 0.51 5.28e-24 Alzheimer's disease (late onset); LIHC cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg00612595 chr21:47717864 NA 0.44 7.1 0.36 7.31e-12 Testicular germ cell tumor; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24158452 chr17:40428550 STAT5B 0.39 6.09 0.31 3e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2251381 0.750 rs8129616 chr21:30520085 C/T cg24692254 chr21:30365293 RNF160 -0.66 -9.85 -0.47 2.62e-20 Selective IgA deficiency; LIHC cis rs6450176 0.909 rs6866586 chr5:53295568 A/C ch.5.1024479R chr5:53302184 ARL15 -0.8 -14.51 -0.62 1.72e-37 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs7772486 0.790 rs2247206 chr6:146216184 C/T cg23711669 chr6:146136114 FBXO30 0.62 10.8 0.5 1.32e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs6430585 0.528 rs6711493 chr2:136692553 A/G cg07169764 chr2:136633963 MCM6 0.96 14.67 0.62 3.92e-38 Corneal structure; LIHC cis rs1005277 0.528 rs2057228 chr10:38515766 T/C cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1448094 0.512 rs1584368 chr12:86245117 A/C cg02569458 chr12:86230093 RASSF9 0.46 6.23 0.32 1.37e-9 Major depressive disorder; LIHC cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg16049864 chr8:95962084 TP53INP1 -0.67 -13.1 -0.58 4.48e-32 Type 2 diabetes; LIHC cis rs10791323 0.517 rs1120247 chr11:133745180 T/G cg06766960 chr11:133703094 NA -0.41 -6.11 -0.31 2.64e-9 Childhood ear infection; LIHC cis rs6691722 0.503 rs4140519 chr1:24708304 C/T cg18323236 chr1:24743029 NIPAL3 0.41 7.4 0.37 1.07e-12 Response to interferon beta in multiple sclerosis; LIHC cis rs66573146 0.656 rs57454756 chr4:6958582 C/T cg00086871 chr4:6988644 TBC1D14 0.84 5.89 0.3 9.3e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg00684032 chr4:1343700 KIAA1530 0.52 7.59 0.38 3.01e-13 Obesity-related traits; LIHC cis rs8058578 1.000 rs8048448 chr16:30692208 T/C cg02466173 chr16:30829666 NA -0.44 -7.06 -0.36 9.37e-12 Multiple myeloma; LIHC cis rs8027181 0.804 rs34661924 chr15:72994564 A/G cg03441853 chr15:73075003 ADPGK 0.28 5.93 0.31 7.48e-9 Triglyceride levels; LIHC cis rs1395 0.710 rs1992291 chr2:27504312 A/G cg17158414 chr2:27665306 KRTCAP3 -0.47 -5.72 -0.3 2.3e-8 Blood metabolite levels; LIHC cis rs240764 0.687 rs1336245 chr6:101197640 A/T cg09795085 chr6:101329169 ASCC3 -0.45 -6.68 -0.34 9.69e-11 Neuroticism; LIHC cis rs6499255 0.951 rs56282083 chr16:69825728 C/T cg15192750 chr16:69999425 NA 0.45 6.78 0.34 5.17e-11 IgE levels; LIHC cis rs344364 0.511 rs2982449 chr16:1947878 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs72781680 0.716 rs2712079 chr2:24082061 G/A cg08917208 chr2:24149416 ATAD2B 0.65 6.57 0.33 1.84e-10 Lymphocyte counts; LIHC cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg18230493 chr5:56204884 C5orf35 -0.45 -6.18 -0.32 1.84e-9 Initial pursuit acceleration; LIHC cis rs963731 0.649 rs6544187 chr2:39232275 G/C cg04010122 chr2:39346883 SOS1 -0.81 -6.07 -0.31 3.32e-9 Corticobasal degeneration; LIHC cis rs7772486 0.701 rs11155438 chr6:145950112 C/G cg23711669 chr6:146136114 FBXO30 0.72 13.13 0.58 3.5e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs926392 0.896 rs4812357 chr20:37683071 C/T cg16355469 chr20:37678765 NA -0.39 -6.43 -0.33 4.26e-10 Dialysis-related mortality; LIHC cis rs2302190 0.882 rs9911609 chr17:56673087 T/C cg05425664 chr17:57184151 TRIM37 -0.47 -5.89 -0.3 9.43e-9 Vitamin D levels; LIHC cis rs1707322 0.752 rs4607935 chr1:46117161 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.57 0.38 3.45e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs826838 0.967 rs11168985 chr12:39045983 A/C cg26384229 chr12:38710491 ALG10B -0.84 -11.07 -0.51 1.51e-24 Heart rate; LIHC cis rs4808199 0.894 rs10418051 chr19:19397789 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.54 7.91 0.39 3.55e-14 Nonalcoholic fatty liver disease; LIHC cis rs13191362 0.935 rs73008456 chr6:163013697 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.89 0.3 9.07e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1814175 0.817 rs11040474 chr11:49708441 G/A cg03929089 chr4:120376271 NA -0.92 -18.79 -0.71 1.28e-54 Height; LIHC cis rs9291683 0.588 rs3796842 chr4:9995851 A/T cg11266682 chr4:10021025 SLC2A9 0.29 5.91 0.3 8.49e-9 Bone mineral density; LIHC cis rs35110281 0.811 rs1122873 chr21:45044672 G/C cg21573476 chr21:45109991 RRP1B -0.57 -10.83 -0.51 1.04e-23 Mean corpuscular volume; LIHC cis rs6545883 0.826 rs777590 chr2:61417145 C/G cg15711740 chr2:61764176 XPO1 -0.43 -5.88 -0.3 9.97e-9 Tuberculosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg03648631 chr4:103749307 UBE2D3 0.52 7.42 0.37 9.17e-13 Lung function (FEV1/FVC); LIHC cis rs2279817 0.775 rs34357655 chr1:18009415 T/C cg21791023 chr1:18019539 ARHGEF10L -0.67 -7.77 -0.39 9.48e-14 Neuroticism; LIHC trans rs7395662 0.526 rs4882001 chr11:48546675 A/G cg15704280 chr7:45808275 SEPT13 -0.46 -6.98 -0.35 1.55e-11 HDL cholesterol; LIHC cis rs7615952 0.599 rs12496921 chr3:125701948 C/G cg05084668 chr3:125655381 ALG1L -0.43 -6.85 -0.35 3.45e-11 Blood pressure (smoking interaction); LIHC cis rs738321 0.701 rs11703601 chr22:38598041 C/T cg25457927 chr22:38595422 NA -0.41 -9.51 -0.46 3.5e-19 Breast cancer; LIHC cis rs2732480 0.577 rs2732486 chr12:48737834 G/A cg21466736 chr12:48725269 NA -0.72 -10.85 -0.51 8.84e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7520050 0.843 rs1707334 chr1:46605728 A/C cg06787764 chr1:46668870 C1orf190;POMGNT1 0.41 5.94 0.31 6.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg22800045 chr5:56110881 MAP3K1 0.68 8.63 0.42 2.36e-16 Initial pursuit acceleration; LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs796364 0.664 rs3106089 chr2:200884615 A/C cg23649088 chr2:200775458 C2orf69 0.51 5.73 0.3 2.19e-8 Schizophrenia; LIHC cis rs2953174 0.786 rs8662 chr2:241517770 G/A cg07929629 chr2:241523174 NA 0.59 6.88 0.35 2.84e-11 Bipolar disorder; LIHC cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg06640241 chr16:89574553 SPG7 0.86 16.18 0.66 3.85e-44 Multiple myeloma (IgH translocation); LIHC cis rs1878931 0.507 rs67218524 chr16:3403057 G/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.58 -7.04 -0.36 1.07e-11 Body mass index (adult); LIHC cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg26119090 chr2:26468346 HADHA;HADHB -1.09 -17.03 -0.68 1.55e-47 Gut microbiome composition (summer); LIHC cis rs7020830 0.867 rs13301916 chr9:37361455 A/C cg14294708 chr9:37120828 ZCCHC7 1.1 21.88 0.76 5.74e-67 Schizophrenia; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg17873919 chr5:134094447 DDX46 -0.42 -6.09 -0.31 3.05e-9 Immature fraction of reticulocytes; LIHC cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg21724239 chr8:58056113 NA 0.58 7.69 0.38 1.63e-13 Developmental language disorder (linguistic errors); LIHC cis rs9902453 1.000 rs28664971 chr17:28437410 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.67 10.53 0.49 1.19e-22 Coffee consumption (cups per day); LIHC cis rs1018836 0.851 rs6986359 chr8:91643162 A/G cg16814680 chr8:91681699 NA -0.56 -8.99 -0.44 1.7e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs992157 0.798 rs2382817 chr2:219151218 A/C cg20019365 chr2:219134978 PNKD;AAMP 0.79 12.77 0.57 8.25e-31 Colorectal cancer; LIHC cis rs2108622 0.727 rs3093216 chr19:15987737 A/G cg13772218 chr19:15982569 NA 0.36 7.35 0.37 1.49e-12 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs10876993 0.928 rs1689595 chr12:58056763 C/T cg15848620 chr12:58087721 OS9 -0.55 -7.67 -0.38 1.81e-13 Celiac disease or Rheumatoid arthritis; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05508245 chr7:6203267 CYTH3 0.39 6.25 0.32 1.25e-9 Hepatitis; LIHC cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg25193494 chr16:90016004 DEF8 -0.44 -5.72 -0.3 2.35e-8 Skin colour saturation; LIHC cis rs8141529 0.748 rs5762874 chr22:29269658 C/G cg15103426 chr22:29168792 CCDC117 0.57 9.26 0.45 2.37e-18 Lymphocyte counts; LIHC cis rs9910055 0.573 rs113184718 chr17:42206543 A/T cg08499158 chr17:42289980 UBTF 0.53 8.64 0.42 2.14e-16 Total body bone mineral density; LIHC cis rs892961 1.000 rs11077907 chr17:75400706 G/A cg05865280 chr17:75406074 SEPT9 0.55 9.73 0.47 6.54e-20 Airflow obstruction; LIHC cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg22800045 chr5:56110881 MAP3K1 0.67 8.51 0.42 5.46e-16 Initial pursuit acceleration; LIHC cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 11.88 0.54 1.7e-27 Platelet count; LIHC cis rs1371867 0.846 rs1660328 chr8:101303450 A/G cg06002616 chr8:101225028 SPAG1 -0.35 -5.76 -0.3 1.83e-8 Atrioventricular conduction; LIHC cis rs17345786 0.906 rs72946021 chr3:101250008 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.53 7.21 0.36 3.61e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs9811920 0.609 rs704583 chr3:99643693 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G 0.41 5.74 0.3 2.12e-8 Axial length; LIHC cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg24549020 chr5:56110836 MAP3K1 0.5 6.46 0.33 3.69e-10 Initial pursuit acceleration; LIHC cis rs9549367 0.756 rs9603814 chr13:113900782 C/T cg18105134 chr13:113819100 PROZ 0.53 9.57 0.46 2.22e-19 Platelet distribution width; LIHC cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg25072359 chr17:41440525 NA 0.37 5.83 0.3 1.3e-8 Menopause (age at onset); LIHC cis rs36051895 0.589 rs7874785 chr9:5196695 C/T cg02405213 chr9:5042618 JAK2 0.66 10.98 0.51 3.03e-24 Pediatric autoimmune diseases; LIHC cis rs1395 0.922 rs6547521 chr2:27488432 G/C cg23587288 chr2:27483067 SLC30A3 -0.3 -5.8 -0.3 1.53e-8 Blood metabolite levels; LIHC cis rs655641 0.734 rs504129 chr11:85690531 A/T cg09030501 chr11:85779252 PICALM -0.52 -6.33 -0.32 7.79e-10 Platelet count; LIHC cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg05025164 chr4:1340916 KIAA1530 -0.73 -10.48 -0.49 1.81e-22 Longevity; LIHC cis rs2295359 0.963 rs12030867 chr1:67627620 T/C cg12940439 chr1:67600707 NA 0.39 7.05 0.36 1e-11 Psoriasis; LIHC trans rs1941687 0.505 rs1389534 chr18:31311161 C/G cg27147174 chr7:100797783 AP1S1 0.43 6.36 0.33 6.39e-10 Subjective well-being (multi-trait analysis);Subjective well-being; LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg24846343 chr22:24311635 DDTL 0.55 10.17 0.48 2.19e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3015497 0.616 rs1389650 chr14:51081449 C/T cg09863266 chr14:51125203 SAV1 -0.38 -6.01 -0.31 4.69e-9 Mean platelet volume; LIHC cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg12311636 chr6:118886798 C6orf204 -0.52 -6.23 -0.32 1.35e-9 Diastolic blood pressure; LIHC cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.92 9.37 0.45 1.01e-18 Platelet count; LIHC cis rs7762018 0.655 rs2184195 chr6:170148397 C/T cg19338460 chr6:170058176 WDR27 -0.38 -5.9 -0.3 8.61e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs589448 0.967 rs2617835 chr12:69753420 C/A cg19645103 chr12:69753606 YEATS4 -0.4 -5.92 -0.3 7.74e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg13397359 chr6:42928475 GNMT 0.63 9.04 0.44 1.18e-17 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg15889976 chr12:124432796 CCDC92 -0.4 -7.4 -0.37 1.06e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg11494091 chr17:61959527 GH2 0.36 6.1 0.31 2.85e-9 Height; LIHC cis rs918629 0.567 rs2348984 chr5:95236010 A/C cg10483112 chr5:95245456 ELL2 -0.38 -6.96 -0.35 1.71e-11 IgG glycosylation; LIHC cis rs208520 0.690 rs207094 chr6:66799009 G/A cg07460842 chr6:66804631 NA -0.84 -9.29 -0.45 1.86e-18 Exhaled nitric oxide output; LIHC cis rs13191362 1.000 rs73035012 chr6:162997279 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.92 0.3 7.85e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs8064299 0.967 rs878905 chr17:72769411 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.74 12.43 0.56 1.65e-29 Monocyte count; LIHC cis rs2282032 0.527 rs41309248 chr14:90767386 C/T cg04374321 chr14:90722782 PSMC1 0.48 6.97 0.35 1.63e-11 Longevity; LIHC cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg00800038 chr16:89945340 TCF25 -0.69 -10.94 -0.51 4.24e-24 Skin colour saturation; LIHC cis rs765787 0.530 rs55920042 chr15:45541577 G/A cg25801113 chr15:45476975 SHF 0.37 6.21 0.32 1.5e-9 Uric acid levels; LIHC cis rs1862618 0.671 rs2591965 chr5:56236176 T/C cg12311346 chr5:56204834 C5orf35 0.45 6.05 0.31 3.87e-9 Initial pursuit acceleration; LIHC cis rs9534288 0.797 rs9534276 chr13:46574317 T/G cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs1707322 0.752 rs8179402 chr1:46142466 C/A cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.38e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9814567 0.806 rs2888670 chr3:134326684 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.41 -5.82 -0.3 1.35e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4638749 0.677 rs12712014 chr2:108812044 A/G cg25838818 chr2:108905173 SULT1C2 0.39 6.99 0.35 1.43e-11 Blood pressure; LIHC cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg19774624 chr17:42201019 HDAC5 -0.8 -12.45 -0.56 1.35e-29 Total body bone mineral density; LIHC cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg21559469 chr19:19431446 KIAA0892;SF4 -0.41 -5.79 -0.3 1.59e-8 Tonsillectomy; LIHC cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg13395646 chr4:1353034 KIAA1530 -0.48 -7.8 -0.39 7.41e-14 Obesity-related traits; LIHC cis rs700651 0.821 rs700663 chr2:198670478 T/A cg10820045 chr2:198174542 NA 0.47 7.03 0.36 1.12e-11 Intracranial aneurysm; LIHC cis rs2153535 0.601 rs1855765 chr6:8444325 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs11711311 1.000 rs12637066 chr3:113527574 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.01 0.44 1.5e-17 IgG glycosylation; LIHC cis rs7639513 0.767 rs7617041 chr3:12709167 A/G cg23032965 chr3:12705835 RAF1 0.65 7.85 0.39 5.27e-14 Itch intensity from mosquito bite; LIHC cis rs9467773 1.000 rs1884948 chr6:26567988 G/A cg11502198 chr6:26597334 ABT1 0.46 6.71 0.34 8.01e-11 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg24209194 chr3:40518798 ZNF619 -0.51 -7.62 -0.38 2.49e-13 Renal cell carcinoma; LIHC cis rs1035144 0.506 rs7150858 chr14:81280425 T/C cg06600135 chr14:81408086 NA -0.45 -7.75 -0.39 1.09e-13 Male sexual orientation; LIHC cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg08280861 chr8:58055591 NA 0.54 6.21 0.32 1.53e-9 Developmental language disorder (linguistic errors); LIHC cis rs4730250 0.707 rs61014091 chr7:106810107 A/C cg02696742 chr7:106810147 HBP1 -0.55 -6.46 -0.33 3.67e-10 Osteoarthritis; LIHC cis rs1144333 1.000 rs2202019 chr1:76299181 G/A cg22875332 chr1:76189707 ACADM 0.44 7.02 0.36 1.18e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg10896456 chr17:42255109 ASB16;C17orf65 -0.56 -10.23 -0.48 1.36e-21 Total body bone mineral density; LIHC cis rs6088590 1.000 rs10048849 chr20:33419680 C/T cg24642439 chr20:33292090 TP53INP2 0.77 10.42 0.49 2.82e-22 Coronary artery disease; LIHC cis rs950776 0.518 rs8025429 chr15:78836362 G/A cg22563815 chr15:78856949 CHRNA5 -0.37 -6.9 -0.35 2.59e-11 Sudden cardiac arrest; LIHC cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg24101359 chr6:42928495 GNMT 0.46 6.2 0.32 1.62e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6066825 0.644 rs926629 chr20:47335736 A/G cg18078177 chr20:47281410 PREX1 0.41 6.67 0.34 1.01e-10 Colorectal cancer; LIHC cis rs1403694 0.695 rs3774292 chr3:186433574 A/T cg12454167 chr3:186435060 KNG1 0.38 8.97 0.44 2.01e-17 Blood protein levels; LIHC cis rs2540917 0.765 rs243081 chr2:60613776 G/A cg00543073 chr2:60773386 BCL11A -0.32 -6.32 -0.32 8.39e-10 Mean corpuscular volume; LIHC cis rs644799 0.965 rs502521 chr11:95533557 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.35 0.68 7.79e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg14004847 chr7:1930337 MAD1L1 -0.46 -6.82 -0.35 4.13e-11 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.96 0.57 1.59e-31 Prudent dietary pattern; LIHC trans rs2727020 0.637 rs1164673 chr11:49328356 C/G cg03929089 chr4:120376271 NA 0.57 9.62 0.46 1.5700000000000001e-19 Coronary artery disease; LIHC cis rs28595532 0.516 rs28552458 chr4:119288363 T/C cg21605333 chr4:119757512 SEC24D 0.83 6.88 0.35 2.93e-11 Cannabis dependence symptom count; LIHC cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg23758822 chr17:41437982 NA 0.94 17.94 0.7 3.44e-51 Menopause (age at onset); LIHC trans rs208515 0.525 rs10944868 chr6:66687508 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.76 8.78 0.43 7.92e-17 Exhaled nitric oxide levels; LIHC cis rs1997103 1.000 rs2331068 chr7:55408220 G/A cg17469321 chr7:55412551 NA 0.47 7.05 0.36 9.81e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs655641 1.000 rs2458499 chr11:85659847 C/T cg09030501 chr11:85779252 PICALM -0.5 -5.88 -0.3 9.81e-9 Platelet count; LIHC trans rs2727020 0.729 rs10839268 chr11:49380328 G/A cg15704280 chr7:45808275 SEPT13 -0.93 -17.77 -0.69 1.67e-50 Coronary artery disease; LIHC cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg27297192 chr10:134578999 INPP5A 0.56 7.71 0.38 1.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7772486 0.875 rs10457795 chr6:146415665 A/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.17 -0.32 1.9e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1814175 0.935 rs11040438 chr11:49622521 G/A cg03929089 chr4:120376271 NA -0.88 -17.28 -0.68 1.62e-48 Height; LIHC trans rs4906332 0.899 rs12888042 chr14:103891709 G/A cg17675199 chr6:35436792 RPL10A 0.31 6.22 0.32 1.49e-9 Coronary artery disease; LIHC cis rs3892630 0.818 rs80137870 chr19:33182750 C/T cg22980127 chr19:33182716 NUDT19 1.05 12.59 0.56 3.91e-30 Red blood cell traits; LIHC cis rs921968 0.541 rs687747 chr2:219399627 T/C cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9733 0.519 rs11800855 chr1:150800995 G/A cg17724175 chr1:150552817 MCL1 0.43 8.68 0.42 1.61e-16 Tonsillectomy; LIHC cis rs7666738 0.761 rs1456210 chr4:98645932 T/G cg05340658 chr4:99064831 C4orf37 0.62 10.86 0.51 8.64e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs748404 0.697 rs505249 chr15:43559960 T/A cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.8 0.35 4.6e-11 Lung cancer; LIHC trans rs6952808 0.608 rs58120505 chr7:2029867 T/C cg04565464 chr8:145669602 NFKBIL2 0.41 6.8 0.35 4.61e-11 Bipolar disorder and schizophrenia; LIHC cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg05890377 chr2:74357713 NA 0.64 12.73 0.57 1.15e-30 Gestational age at birth (maternal effect); LIHC cis rs12594515 1.000 rs8032361 chr15:45988553 T/C cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.84e-19 Waist circumference;Weight; LIHC cis rs875971 0.545 rs12671152 chr7:65776127 G/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.38 7.32 0.37 1.78e-12 Aortic root size; LIHC cis rs17818399 0.502 rs1451152 chr2:46800150 C/T cg02822958 chr2:46747628 ATP6V1E2 0.41 6.51 0.33 2.64e-10 Height; LIHC trans rs9747201 1.000 rs12943668 chr17:80109930 C/T cg07393940 chr7:158741817 NA -0.57 -6.95 -0.35 1.85e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4423214 1.000 rs7944926 chr11:71165625 A/G cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC cis rs6502050 0.835 rs8078950 chr17:80122327 T/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs7635838 0.963 rs7627171 chr3:11413429 G/C cg00170343 chr3:11313890 ATG7 0.45 7.36 0.37 1.39e-12 HDL cholesterol; LIHC cis rs7520050 0.751 rs592214 chr1:46024505 G/A cg03146154 chr1:46216737 IPP -0.46 -7.28 -0.37 2.3e-12 Red blood cell count;Reticulocyte count; LIHC cis rs11758351 1.000 rs16891397 chr6:26200256 C/T cg03854865 chr6:26224070 HIST1H3E 0.63 6.97 0.35 1.59e-11 Gout;Renal underexcretion gout; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26887379 chr1:12677936 DHRS3 0.47 6.33 0.32 7.82e-10 Pancreatic cancer; LIHC cis rs11098699 0.821 rs12500715 chr4:124230078 T/C cg09941581 chr4:124220074 SPATA5 0.33 6.57 0.33 1.83e-10 Mosquito bite size; LIHC trans rs2591576 0.935 rs830230 chr5:165402097 T/C cg02030008 chr7:157476930 PTPRN2 -0.33 -6.16 -0.32 2.04e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs59797486 chr8:58174435 T/C cg21724239 chr8:58056113 NA 0.46 6.09 0.31 3.08e-9 Developmental language disorder (linguistic errors); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg08451977 chr7:100849825 PLOD3 -0.45 -6.9 -0.35 2.54e-11 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03700308 chr20:49575492 MOCS3;DPM1 0.45 6.08 0.31 3.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6439153 0.933 rs11711812 chr3:128708554 G/A cg25356066 chr3:128598488 ACAD9 0.42 5.74 0.3 2.08e-8 Pneumococcal bacteremia; LIHC cis rs9790314 0.934 rs462413 chr3:161101587 T/C cg04691961 chr3:161091175 C3orf57 -0.44 -6.81 -0.35 4.45e-11 Morning vs. evening chronotype; LIHC cis rs6089584 0.507 rs6061989 chr20:60627893 C/T cg06108461 chr20:60628389 TAF4 -0.65 -8.98 -0.44 1.87e-17 Body mass index; LIHC trans rs6951245 0.580 rs77101766 chr7:1122438 A/G cg13565492 chr6:43139072 SRF -0.81 -7.37 -0.37 1.33e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs921968 0.643 rs4674305 chr2:219293326 C/T cg18887096 chr2:219472410 PLCD4 0.35 5.97 0.31 5.94e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg12463550 chr7:65579703 CRCP -0.67 -7.01 -0.35 1.25e-11 Diabetic kidney disease; LIHC cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg23990641 chr6:118823964 C6orf204;BRD7P3 -0.5 -6.2 -0.32 1.66e-9 Diastolic blood pressure; LIHC cis rs3806843 0.735 rs801168 chr5:140080298 A/G cg16179182 chr5:140090404 VTRNA1-1 0.38 6.25 0.32 1.2e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4586057 0.514 rs7089472 chr10:92663108 C/T cg14313238 chr10:92632228 RPP30 0.4 6.87 0.35 3.04e-11 Economic and political preferences (time); LIHC cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg11645453 chr3:52864694 ITIH4 0.21 5.74 0.3 2.09e-8 Bipolar disorder; LIHC cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg13395646 chr4:1353034 KIAA1530 -0.63 -9.0 -0.44 1.55e-17 Obesity-related traits; LIHC cis rs9486719 1.000 rs2472886 chr6:96864876 C/T cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs2075371 0.932 rs1862052 chr7:133981227 G/A cg11752832 chr7:134001865 SLC35B4 0.48 6.1 0.31 2.86e-9 Mean platelet volume; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg02475777 chr4:1388615 CRIPAK 0.57 8.52 0.42 5.29e-16 Longevity; LIHC cis rs2153535 0.580 rs4960421 chr6:8459292 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.72 0.43 1.21e-16 Motion sickness; LIHC cis rs7903847 0.642 rs11189206 chr10:99167802 T/C cg08345082 chr10:99160200 RRP12 -0.4 -7.06 -0.36 9.47e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs7618501 1.000 rs34451146 chr3:49813013 C/T cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.08e-11 Intelligence (multi-trait analysis); LIHC cis rs1451375 0.617 rs1807066 chr7:50543683 T/C cg14593290 chr7:50529359 DDC -0.65 -10.25 -0.48 1.15e-21 Malaria; LIHC cis rs1008375 0.897 rs3733577 chr4:17649233 T/G cg16339924 chr4:17578868 LAP3 0.42 5.91 0.3 8.18e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs868036 0.681 rs13329567 chr15:68104367 C/T cg24579218 chr15:68104479 NA -0.35 -5.9 -0.3 8.7e-9 Restless legs syndrome; LIHC cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.6 0.38 2.79e-13 Bipolar disorder; LIHC cis rs11690935 0.959 rs2292815 chr2:172586651 C/G cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.68 -0.69 3.98e-50 Schizophrenia; LIHC cis rs9378688 0.654 rs9391946 chr6:2263097 A/G cg12303981 chr6:2244766 GMDS -0.45 -6.04 -0.31 4.11e-9 Caudate nucleus volume; LIHC cis rs67478160 0.619 rs12897150 chr14:104319530 A/T cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.55 -0.38 4.11e-13 Schizophrenia; LIHC cis rs9790314 0.580 rs960212 chr3:161047974 C/T cg17135325 chr3:160939158 NMD3 0.41 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs1023500 0.551 rs133379 chr22:42468535 A/G cg00645731 chr22:42541494 CYP2D7P1 0.4 6.2 0.32 1.61e-9 Schizophrenia; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg01587390 chr19:10221818 PPAN-P2RY11;P2RY11;PPAN 0.42 6.22 0.32 1.46e-9 Electroencephalogram traits; LIHC trans rs3942852 0.774 rs10838814 chr11:48187178 G/A cg15704280 chr7:45808275 SEPT13 -0.59 -7.99 -0.4 2.04e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs910316 0.967 rs175432 chr14:75615246 C/G cg08847533 chr14:75593920 NEK9 -0.87 -18.5 -0.71 1.85e-53 Height; LIHC trans rs9747201 0.832 rs4072580 chr17:80160337 A/C cg07393940 chr7:158741817 NA 0.55 6.56 0.33 1.99e-10 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2197308 0.715 rs11181816 chr12:37911626 A/G cg26384229 chr12:38710491 ALG10B -0.47 -6.64 -0.34 1.23e-10 Morning vs. evening chronotype; LIHC cis rs7312933 1.000 rs7312933 chr12:42503467 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.48 -7.03 -0.36 1.12e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs8067354 0.872 rs2645483 chr17:57848184 T/G cg13753209 chr17:57696993 CLTC 0.58 8.64 0.42 2.22e-16 Hemoglobin concentration; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg24262715 chr15:44038991 PDIA3;CATSPER2P1 0.39 6.24 0.32 1.32e-9 Calcium levels; LIHC cis rs7756236 0.521 rs9470363 chr6:36624713 G/A cg08179530 chr6:36648295 CDKN1A 0.42 6.34 0.32 7.29e-10 QRS duration; LIHC cis rs16854884 0.657 rs7610378 chr3:143711298 G/A cg06585982 chr3:143692056 C3orf58 0.62 8.71 0.43 1.32e-16 Economic and political preferences (feminism/equality); LIHC cis rs9486715 0.867 rs9386500 chr6:96889845 A/C cg06623918 chr6:96969491 KIAA0776 0.83 14.45 0.62 2.7e-37 Headache; LIHC cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg11764359 chr7:65958608 NA 0.58 6.04 0.31 3.97e-9 Diabetic kidney disease; LIHC cis rs2180341 1.000 rs2144742 chr6:127595786 C/A cg27446573 chr6:127587934 RNF146 1.0 15.32 0.64 1.06e-40 Breast cancer; LIHC cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg00149659 chr3:10157352 C3orf10 0.68 7.12 0.36 6.57e-12 Alzheimer's disease; LIHC cis rs6570726 0.791 rs10872577 chr6:145900560 G/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.38 -0.33 5.85e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs35740288 0.539 rs11629991 chr15:86336664 A/G cg20737812 chr15:86336631 KLHL25 -0.42 -5.83 -0.3 1.27e-8 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg01401336 chr17:2606734 KIAA0664 0.37 6.46 0.33 3.5e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs9503598 0.636 rs7766753 chr6:3467708 A/C cg00476032 chr6:3446245 SLC22A23 0.4 7.7 0.38 1.49e-13 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs7520050 0.807 rs4468203 chr1:46113272 T/C cg03146154 chr1:46216737 IPP 0.5 8.54 0.42 4.4e-16 Red blood cell count;Reticulocyte count; LIHC cis rs66573146 0.572 rs66734745 chr4:6948765 T/C cg00086871 chr4:6988644 TBC1D14 0.8 6.06 0.31 3.61e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs12477438 0.798 rs6716913 chr2:99580641 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.78 -9.95 -0.47 1.22e-20 Chronic sinus infection; LIHC cis rs760805 0.965 rs11249203 chr1:25258585 G/C cg22509179 chr1:25234806 RUNX3 -0.38 -7.91 -0.39 3.53e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs1577917 0.682 rs1173419 chr6:86402163 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.49 -9.92 -0.47 1.49e-20 Response to antipsychotic treatment; LIHC cis rs6867032 0.917 rs10474734 chr5:2004208 A/G cg26168224 chr5:2018326 NA 0.29 7.18 0.36 4.37e-12 Gut microbiome composition (winter); LIHC cis rs9916302 0.861 rs3889368 chr17:37683231 C/T cg07936489 chr17:37558343 FBXL20 -0.83 -13.26 -0.58 1.16e-32 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.913 rs6591346 chr11:68384618 T/A cg20283391 chr11:68216788 NA -0.53 -8.05 -0.4 1.35e-14 Total body bone mineral density; LIHC cis rs13108904 0.539 rs13135102 chr4:1330983 A/C cg00684032 chr4:1343700 KIAA1530 0.58 8.6 0.42 2.89e-16 Obesity-related traits; LIHC trans rs7618501 0.501 rs7627864 chr3:49926613 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.46 6.88 0.35 2.86e-11 Intelligence (multi-trait analysis); LIHC cis rs10508774 0.925 rs12416437 chr10:32751526 A/T cg01819863 chr10:32635814 EPC1 0.65 6.01 0.31 4.72e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs7674212 0.570 rs12501621 chr4:104095505 T/G cg16471864 chr4:38666270 KLF3;FLJ13197 -0.43 -6.1 -0.31 2.87e-9 Type 2 diabetes; LIHC cis rs6502050 0.835 rs4789737 chr17:80123269 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg22098324 chr2:232645906 PDE6D 0.48 6.41 0.33 4.93e-10 Glycated hemoglobin levels; LIHC cis rs17685 0.753 rs4732595 chr7:75755139 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.3 -0.32 8.95e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs921968 0.643 rs1516086 chr2:219431535 C/T cg02985541 chr2:219472218 PLCD4 0.45 8.5 0.42 6.04e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs711245 0.699 rs3770818 chr2:36769497 T/G cg01206211 chr2:36825736 FEZ2 0.46 7.36 0.37 1.4e-12 Height; LIHC cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC cis rs12477438 0.798 rs6712338 chr2:99585457 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -10.6 -0.5 6.66e-23 Chronic sinus infection; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg01866215 chr16:3150293 NA 0.51 6.49 0.33 3.09e-10 Hepatitis; LIHC cis rs365132 0.791 rs55954117 chr5:176454075 A/G cg16309518 chr5:176445507 NA -0.52 -9.69 -0.46 8.91e-20 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs9300255 0.537 rs2695482 chr12:123623174 C/T cg00376283 chr12:123451042 ABCB9 0.57 6.48 0.33 3.13e-10 Neutrophil percentage of white cells; LIHC cis rs2777491 1.000 rs316609 chr15:41743828 T/A cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.28 -0.45 2.06e-18 Ulcerative colitis; LIHC cis rs17125944 0.615 rs8019585 chr14:53374843 G/A cg00686598 chr14:53173677 PSMC6 0.85 9.22 0.45 3.1e-18 Alzheimer's disease (late onset); LIHC cis rs7044106 0.762 rs10491783 chr9:123450155 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.9 0.51 6.28e-24 Hip circumference adjusted for BMI; LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 8.89e-15 Prudent dietary pattern; LIHC cis rs2976388 0.632 rs2585139 chr8:143808175 C/G cg06565975 chr8:143823917 SLURP1 0.32 6.03 0.31 4.27e-9 Urinary tract infection frequency; LIHC trans rs10411161 0.702 rs7256926 chr19:52391988 A/G cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs2302190 0.882 rs9903050 chr17:56636908 T/C cg12560992 chr17:57184187 TRIM37 0.68 8.8 0.43 7e-17 Vitamin D levels; LIHC trans rs916888 0.773 rs538628 chr17:44787313 G/C cg13957321 chr17:43675089 NA 0.5 7.92 0.39 3.36e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4722404 0.800 rs6943609 chr7:3141596 G/A cg19214707 chr7:3157722 NA 0.32 5.85 0.3 1.17e-8 Atopic dermatitis; LIHC cis rs7523273 0.597 rs4844390 chr1:207934849 A/G cg22525895 chr1:207977042 MIR29B2 -0.63 -7.23 -0.36 3.15e-12 Schizophrenia; LIHC cis rs6952808 0.501 rs3778999 chr7:2180885 G/A cg21782813 chr7:2030301 MAD1L1 0.37 6.4 0.33 5.17e-10 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.82 0.39 6.54e-14 Prudent dietary pattern; LIHC cis rs10861342 1.000 rs10861360 chr12:105570041 A/G cg23923672 chr12:105501055 KIAA1033 -0.58 -7.1 -0.36 7.18e-12 IgG glycosylation; LIHC cis rs9918079 0.560 rs6414767 chr4:15655721 A/G cg24225360 chr4:15471699 CC2D2A -0.39 -6.17 -0.32 1.9e-9 Obesity-related traits; LIHC cis rs782590 0.837 rs2627769 chr2:55927288 G/C cg18811423 chr2:55921094 PNPT1 1.04 17.12 0.68 7.05e-48 Metabolic syndrome; LIHC cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg10755058 chr3:40428713 ENTPD3 0.39 6.61 0.34 1.45e-10 Renal cell carcinoma; LIHC cis rs55823223 0.564 rs58363746 chr17:73850819 C/T cg08125733 chr17:73851984 WBP2 0.82 11.89 0.54 1.6e-27 Psoriasis; LIHC cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg12311346 chr5:56204834 C5orf35 -0.56 -7.35 -0.37 1.46e-12 Initial pursuit acceleration; LIHC cis rs2404602 0.583 rs4381566 chr15:76589262 A/G cg22467129 chr15:76604101 ETFA -0.39 -6.44 -0.33 4e-10 Blood metabolite levels; LIHC cis rs12188164 0.543 rs2672757 chr5:454732 A/G cg24955955 chr5:415729 AHRR 0.32 6.64 0.34 1.27e-10 Cystic fibrosis severity; LIHC cis rs4243830 0.737 rs6692747 chr1:6610049 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 0.84 8.66 0.42 1.88e-16 Body mass index; LIHC cis rs2742417 0.603 rs2742453 chr3:45765858 G/A cg04837898 chr3:45731254 SACM1L -0.51 -8.61 -0.42 2.63e-16 Response to anti-depressant treatment in major depressive disorder; LIHC trans rs10838798 0.523 rs11039593 chr11:48240112 A/G cg15704280 chr7:45808275 SEPT13 -0.41 -6.06 -0.31 3.62e-9 Height; LIHC cis rs3736485 0.966 rs6493498 chr15:51754451 T/C cg08986416 chr15:51914746 DMXL2 -0.4 -5.86 -0.3 1.09e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10178409 1 rs10178409 chr2:73855507 G/T cg20560298 chr2:73613845 ALMS1 -0.52 -5.95 -0.31 6.81e-9 Urinary metabolites; LIHC cis rs8062405 1.000 rs62036616 chr16:28826307 A/G cg00204512 chr16:28754710 NA 0.38 6.9 0.35 2.55e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6748734 1.000 rs3936203 chr2:241834654 C/T cg09990169 chr2:241835740 C2orf54 0.66 9.26 0.45 2.4e-18 Urinary metabolites; LIHC cis rs3862030 0.694 rs12781742 chr10:104227469 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.4 -0.37 1.04e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs11023332 0.641 rs4281505 chr11:14800660 A/G cg19336497 chr11:14380999 RRAS2 -0.35 -6.18 -0.32 1.78e-9 Adiponectin levels;Vitamin D levels; LIHC cis rs8081395 0.805 rs1295927 chr17:57929535 A/G cg02344993 chr17:57696989 CLTC 0.45 7.5 0.38 5.48e-13 White blood cell count; LIHC trans rs3942852 0.774 rs924715 chr11:48181060 G/A cg15704280 chr7:45808275 SEPT13 -0.59 -8.0 -0.4 1.95e-14 Acute lymphoblastic leukemia (childhood); LIHC cis rs2463822 1.000 rs1406384 chr11:62083530 A/G cg06239285 chr11:62104954 ASRGL1 -0.91 -6.77 -0.34 5.63e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs9549367 0.789 rs71446682 chr13:113894908 A/G cg18105134 chr13:113819100 PROZ -0.66 -11.52 -0.53 3.63e-26 Platelet distribution width; LIHC trans rs9929218 0.954 rs1981871 chr16:68819007 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.6 -8.51 -0.42 5.45e-16 Colorectal cancer; LIHC cis rs477895 0.713 rs3802933 chr11:63988102 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 9.91 0.47 1.61e-20 Mean platelet volume; LIHC cis rs6831352 0.734 rs3018046 chr4:100030388 C/T cg12011299 chr4:100065546 ADH4 0.56 9.87 0.47 2.2e-20 Alcohol dependence; LIHC cis rs67981189 0.593 rs7143595 chr14:71522001 A/T cg15816911 chr14:71606274 NA 0.42 6.7 0.34 8.41e-11 Schizophrenia; LIHC cis rs6952808 0.792 rs2056481 chr7:1955435 A/G cg14004847 chr7:1930337 MAD1L1 -0.48 -6.79 -0.34 4.89e-11 Bipolar disorder and schizophrenia; LIHC cis rs2153535 0.580 rs4960423 chr6:8477210 C/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs3736594 0.513 rs62138964 chr2:27814438 C/T cg27432699 chr2:27873401 GPN1 0.46 6.92 0.35 2.29e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs55665837 0.701 rs10160597 chr11:14603992 G/A cg00085434 chr11:14927489 NA 0.43 6.04 0.31 4.02e-9 Vitamin D levels; LIHC cis rs11166927 1.000 rs10435690 chr8:140802093 C/T cg16909799 chr8:140841666 TRAPPC9 0.46 7.59 0.38 3.09e-13 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs8060686 0.641 rs28508024 chr16:68126606 T/C cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.69e-8 HDL cholesterol;Metabolic syndrome; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg05772935 chr16:1790400 MAPK8IP3 0.61 6.09 0.31 3.01e-9 Mean platelet volume; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC trans rs1728785 1.000 rs698728 chr16:68625253 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.51 6.28 0.32 1.05e-9 Ulcerative colitis; LIHC cis rs7100689 0.646 rs10749579 chr10:82140959 C/T cg01528321 chr10:82214614 TSPAN14 0.84 12.03 0.55 4.88e-28 Post bronchodilator FEV1; LIHC cis rs798554 0.759 rs2644309 chr7:2889034 T/C cg04166393 chr7:2884313 GNA12 0.54 8.59 0.42 3.03e-16 Height; LIHC trans rs13325613 0.748 rs114115904 chr3:46268664 C/T cg26337592 chr1:153642686 ILF2 0.68 6.18 0.32 1.81e-9 Monocyte count; LIHC cis rs35110281 0.748 rs2838324 chr21:44999820 T/C cg04455712 chr21:45112962 RRP1B 0.49 8.18 0.4 5.69e-15 Mean corpuscular volume; LIHC cis rs67478160 0.634 rs2024669 chr14:104275602 G/C cg01849466 chr14:104193079 ZFYVE21 -0.5 -8.32 -0.41 2.17e-15 Schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14472810 chr7:1936732 MAD1L1 0.42 6.3 0.32 9.2e-10 Longevity; LIHC cis rs9303401 0.580 rs12946396 chr17:57164195 T/A cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.0 0.58 1.11e-31 Cognitive test performance; LIHC cis rs6952808 0.594 rs3778965 chr7:2138296 G/A cg21782813 chr7:2030301 MAD1L1 0.38 6.48 0.33 3.16e-10 Bipolar disorder and schizophrenia; LIHC cis rs1538970 0.816 rs11211124 chr1:45962409 T/C cg05343316 chr1:45956843 TESK2 0.63 9.49 0.46 4.11e-19 Platelet count; LIHC cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg24549020 chr5:56110836 MAP3K1 0.49 6.29 0.32 9.61e-10 Initial pursuit acceleration; LIHC cis rs10838687 0.867 rs2957873 chr11:47249294 G/A cg26139080 chr11:47293733 MADD 0.42 6.01 0.31 4.67e-9 Proinsulin levels; LIHC cis rs7116495 0.881 rs615000 chr11:71802952 A/C cg26138937 chr11:71823887 C11orf51 -0.8 -7.88 -0.39 4.5e-14 Severe influenza A (H1N1) infection; LIHC cis rs7095944 0.583 rs12218394 chr10:126480591 G/C cg20435097 chr10:126320824 FAM53B 0.34 5.87 0.3 1.06e-8 Asthma; LIHC cis rs1568889 1.000 rs7931847 chr11:28175245 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.91 0.35 2.36e-11 Bipolar disorder; LIHC cis rs9649213 0.614 rs62479858 chr7:97924226 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.57 -9.98 -0.47 9.72e-21 Prostate cancer (SNP x SNP interaction); LIHC cis rs9534288 0.731 rs7981685 chr13:46605495 G/A cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs2404602 0.735 rs4886495 chr15:76738959 C/T cg03037974 chr15:76606532 NA 0.63 10.97 0.51 3.47e-24 Blood metabolite levels; LIHC cis rs8062405 1.000 rs7498665 chr16:28883241 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2806561 0.704 rs663942 chr1:23522476 G/A cg12483005 chr1:23474871 LUZP1 0.47 7.25 0.36 2.89e-12 Height; LIHC cis rs7044106 0.615 rs10818470 chr9:123359204 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.53 7.75 0.39 1.07e-13 Hip circumference adjusted for BMI; LIHC cis rs7208859 0.623 rs8080882 chr17:29081146 G/A cg13385521 chr17:29058706 SUZ12P 0.81 7.96 0.4 2.64e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs753778 0.628 rs1045248 chr8:142204326 C/G cg18755752 chr8:142205143 DENND3 -0.38 -6.86 -0.35 3.25e-11 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg13409248 chr3:40428643 ENTPD3 0.5 8.43 0.41 9.5e-16 Renal cell carcinoma; LIHC cis rs1499614 0.901 rs3936 chr7:66126489 C/T cg18252515 chr7:66147081 NA -1.34 -18.13 -0.7 5.81e-52 Gout; LIHC cis rs12291225 0.585 rs34171876 chr11:14353957 G/C cg19336497 chr11:14380999 RRAS2 -0.68 -14.14 -0.61 4.53e-36 Sense of smell; LIHC cis rs3820500 0.543 rs7539143 chr1:117977324 G/A cg20383390 chr1:117909022 MAN1A2 0.46 5.91 0.3 8.13e-9 Pneumonia; LIHC cis rs1555322 0.530 rs6060341 chr20:33863633 C/T cg03689076 chr20:33865952 NA -0.56 -6.48 -0.33 3.14e-10 Attention deficit hyperactivity disorder; LIHC cis rs74233809 1.000 rs77420391 chr10:104945823 G/A cg03493300 chr10:104813866 CNNM2 0.48 6.16 0.32 2.02e-9 Birth weight; LIHC cis rs72781680 0.898 rs72782106 chr2:24022009 A/G cg08917208 chr2:24149416 ATAD2B 0.96 8.09 0.4 1.02e-14 Lymphocyte counts; LIHC cis rs9303401 0.659 rs61291849 chr17:56909867 T/C cg25039879 chr17:56429692 SUPT4H1 0.75 8.6 0.42 2.85e-16 Cognitive test performance; LIHC cis rs2749592 0.513 rs1208708 chr10:38085576 A/G cg00409905 chr10:38381863 ZNF37A -0.53 -9.17 -0.44 4.41e-18 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg00166722 chr3:10149974 C3orf24 0.53 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC cis rs6430585 0.583 rs2839740 chr2:136648883 G/T cg07169764 chr2:136633963 MCM6 1.35 22.78 0.78 1.47e-70 Corneal structure; LIHC cis rs425277 0.917 rs262656 chr1:2088754 A/C cg24578937 chr1:2090814 PRKCZ 0.5 9.1 0.44 7.35e-18 Height; LIHC cis rs116095464 0.558 rs28558836 chr5:285748 C/G cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs1801251 1.000 rs283469 chr2:233656997 G/T cg08000102 chr2:233561755 GIGYF2 0.76 11.33 0.52 1.79e-25 Coronary artery disease; LIHC cis rs2404602 0.647 rs920712 chr15:77033934 G/A cg23625390 chr15:77176239 SCAPER -0.55 -9.27 -0.45 2.14e-18 Blood metabolite levels; LIHC cis rs6750047 0.771 rs1056836 chr2:38298203 C/G cg07380506 chr2:38303506 CYP1B1 -0.59 -7.6 -0.38 2.85e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs17401966 0.838 rs8019 chr1:10366487 T/G cg15208524 chr1:10270712 KIF1B 0.39 6.03 0.31 4.2e-9 Hepatocellular carcinoma; LIHC cis rs4665809 0.818 rs35413760 chr2:26267137 C/A cg04944784 chr2:26401820 FAM59B 0.61 6.68 0.34 9.45e-11 Gut microbiome composition (summer); LIHC cis rs68170813 0.559 rs78440378 chr7:106962782 C/A cg02696742 chr7:106810147 HBP1 -0.5 -5.85 -0.3 1.17e-8 Coronary artery disease; LIHC cis rs1005277 0.579 rs2749616 chr10:38510993 A/T cg03665457 chr10:38645376 HSD17B7P2 -0.45 -6.49 -0.33 3.09e-10 Extrinsic epigenetic age acceleration; LIHC cis rs208520 0.690 rs207114 chr6:66791703 C/T cg07460842 chr6:66804631 NA -0.82 -9.26 -0.45 2.34e-18 Exhaled nitric oxide output; LIHC cis rs986417 0.748 rs10142927 chr14:61041956 A/G cg27398547 chr14:60952738 C14orf39 0.71 8.29 0.41 2.67e-15 Gut microbiota (bacterial taxa); LIHC cis rs11792861 0.926 rs72607169 chr9:111832471 A/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.7 -0.34 8.54e-11 Menarche (age at onset); LIHC cis rs7903847 0.620 rs954149 chr10:99122936 G/A cg08345082 chr10:99160200 RRP12 -0.36 -5.96 -0.31 6.14e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6933660 0.536 rs3800274 chr6:151759192 T/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.45 -6.19 -0.32 1.74e-9 Menarche (age at onset); LIHC cis rs1789 0.903 rs6850422 chr4:15682437 C/T cg24225360 chr4:15471699 CC2D2A -0.38 -5.85 -0.3 1.12e-8 Blood protein levels; LIHC cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg06481639 chr22:41940642 POLR3H -0.72 -6.74 -0.34 6.5500000000000006e-11 Vitiligo; LIHC cis rs4148883 0.675 rs28762430 chr4:100119257 C/A cg12011299 chr4:100065546 ADH4 0.34 6.87 0.35 3.06e-11 Alcohol dependence; LIHC cis rs2741335 0.876 rs2565058 chr8:27337207 G/T cg07150473 chr8:27338183 CHRNA2 -0.44 -6.37 -0.33 6.18e-10 Response to zileuton treatment in asthma (FEV1 change interaction); LIHC trans rs2243480 1.000 rs160637 chr7:65584318 C/T cg10756647 chr7:56101905 PSPH 1.07 13.4 0.59 3.25e-33 Diabetic kidney disease; LIHC cis rs11122272 0.735 rs2790873 chr1:231539685 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.2 0.45 3.69e-18 Hemoglobin concentration; LIHC cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg19774624 chr17:42201019 HDAC5 -0.8 -12.48 -0.56 1.06e-29 Total body bone mineral density; LIHC cis rs6701037 0.566 rs10753091 chr1:175134571 T/C cg17845761 chr1:175162550 KIAA0040 0.41 6.96 0.35 1.76e-11 Alcohol dependence; LIHC cis rs6500602 0.727 rs10451135 chr16:4580214 T/C cg08645402 chr16:4508243 NA 0.42 8.06 0.4 1.32e-14 Schizophrenia; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg00691206 chr18:14132697 ZNF519 0.4 6.78 0.34 5.32e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4819052 0.851 rs7275468 chr21:46656499 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 9.8 0.47 3.91e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg18306943 chr3:40428807 ENTPD3 0.41 7.08 0.36 8.07e-12 Renal cell carcinoma; LIHC cis rs8180040 1.000 rs295428 chr3:47359262 G/T cg27129171 chr3:47204927 SETD2 0.64 10.95 0.51 4.12e-24 Colorectal cancer; LIHC cis rs507080 0.733 rs673547 chr11:118573339 G/A cg04173919 chr11:118528438 PHLDB1 0.32 6.02 0.31 4.44e-9 Serum metabolite levels; LIHC cis rs7617773 0.780 rs13081169 chr3:48356797 G/A cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs8180040 0.966 rs11130128 chr3:47486632 T/C cg27129171 chr3:47204927 SETD2 -0.56 -9.45 -0.46 5.33e-19 Colorectal cancer; LIHC cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg08859206 chr1:53392774 SCP2 0.38 6.14 0.32 2.31e-9 Monocyte count; LIHC cis rs9381040 0.655 rs2268193 chr6:41024625 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.42 -0.33 4.67e-10 Alzheimer's disease (late onset); LIHC cis rs67478160 0.619 rs12437066 chr14:104236844 A/C cg01849466 chr14:104193079 ZFYVE21 -0.53 -9.23 -0.45 2.8e-18 Schizophrenia; LIHC cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg15664640 chr17:80829946 TBCD 0.38 5.95 0.31 6.58e-9 Glycated hemoglobin levels; LIHC cis rs6752107 0.840 rs2119505 chr2:234154651 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.52 7.76 0.39 1.01e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10464366 0.510 rs62442212 chr7:39146896 A/C cg15212455 chr7:39170539 POU6F2 0.4 7.09 0.36 7.83e-12 IgG glycosylation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07950158 chr19:45874032 ERCC2 0.47 6.89 0.35 2.72e-11 Cognitive function; LIHC cis rs2933343 1.000 rs789227 chr3:128600585 C/G cg25356066 chr3:128598488 ACAD9 0.55 7.28 0.37 2.32e-12 IgG glycosylation; LIHC cis rs910316 0.763 rs1548807 chr14:75479582 T/G cg11812906 chr14:75593930 NEK9 0.71 13.25 0.58 1.26e-32 Height; LIHC cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg11764359 chr7:65958608 NA -0.57 -5.95 -0.31 6.6e-9 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16279940 chr3:108308523 DZIP3;KIAA1524 -0.46 -6.39 -0.33 5.38e-10 Pancreatic cancer; LIHC cis rs7587476 0.689 rs78989396 chr2:215714816 C/T cg04530015 chr2:215796436 ABCA12 -0.37 -5.91 -0.3 8.43e-9 Neuroblastoma; LIHC cis rs1799949 1.000 rs8077486 chr17:41212805 C/T cg05368731 chr17:41323189 NBR1 0.68 11.41 0.52 9.26e-26 Menopause (age at onset); LIHC cis rs921968 0.541 rs599973 chr2:219387273 C/G cg02985541 chr2:219472218 PLCD4 0.42 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs6762 0.642 rs28692469 chr11:839675 T/C cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.61 -0.46 1.6e-19 Mean platelet volume; LIHC trans rs11088226 0.681 rs2833912 chr21:33949822 G/A cg09050820 chr6:167586206 TCP10L2 0.89 15.25 0.64 1.96e-40 Gastritis; LIHC cis rs9527 0.569 rs10883801 chr10:104677887 A/C cg15744005 chr10:104629667 AS3MT -0.29 -5.81 -0.3 1.41e-8 Arsenic metabolism; LIHC cis rs9300255 0.539 rs1969355 chr12:123742061 G/A cg00376283 chr12:123451042 ABCB9 0.65 9.87 0.47 2.22e-20 Neutrophil percentage of white cells; LIHC cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg15691649 chr6:25882328 NA -0.54 -6.8 -0.35 4.71e-11 Intelligence (multi-trait analysis); LIHC cis rs11231694 1.000 rs11231694 chr11:63862882 G/C cg18375707 chr11:64034959 PLCB3 -0.44 -5.75 -0.3 1.95e-8 Hip circumference adjusted for BMI; LIHC cis rs317689 0.684 rs315125 chr12:69758884 C/T cg22834771 chr12:69754056 YEATS4 -0.39 -5.91 -0.3 8.41e-9 Response to diuretic therapy; LIHC cis rs2288073 0.965 rs6545340 chr2:24422269 C/G cg06627628 chr2:24431161 ITSN2 -0.62 -8.23 -0.41 3.95e-15 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs7520050 0.966 rs2275426 chr1:46487552 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.82 0.3 1.35e-8 Red blood cell count;Reticulocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10581632 chr12:56360715 CDK2;SILV 0.47 6.55 0.33 2.1e-10 Lung function (FEV1/FVC); LIHC cis rs1355223 0.902 rs11819839 chr11:34715778 C/T cg11058730 chr11:34937778 PDHX;APIP -0.45 -6.42 -0.33 4.62e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg01788221 chr16:89496183 ANKRD11 -0.37 -5.88 -0.3 9.74e-9 Multiple myeloma (IgH translocation); LIHC cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg09904177 chr6:26538194 HMGN4 0.57 11.2 0.52 5e-25 Intelligence (multi-trait analysis); LIHC cis rs6665290 0.594 rs17592479 chr1:227173892 T/A cg10327440 chr1:227177885 CDC42BPA -1.13 -27.12 -0.83 3.15e-87 Myeloid white cell count; LIHC cis rs6876835 0.553 rs7720397 chr5:6598893 T/C cg04204831 chr5:6583394 LOC255167 0.4 6.24 0.32 1.27e-9 Visceral fat; LIHC cis rs700651 0.786 rs58224025 chr2:198821988 G/A cg10820045 chr2:198174542 NA 0.48 7.4 0.37 1.09e-12 Intracranial aneurysm; LIHC trans rs9929218 0.954 rs12928043 chr16:68828885 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.2 -0.41 5.07e-15 Colorectal cancer; LIHC cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10463316 0.894 rs10476980 chr5:150764157 A/G cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.05e-10 Metabolite levels (Pyroglutamine); LIHC cis rs9733 0.596 rs72702580 chr1:150691285 A/T cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.45e-9 Tonsillectomy; LIHC cis rs6061231 0.505 rs13037253 chr20:60928724 G/A cg06026331 chr20:60912101 LAMA5 0.61 8.86 0.43 4.47e-17 Colorectal cancer; LIHC cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.73 0.57 1.17e-30 Prudent dietary pattern; LIHC cis rs910316 0.763 rs175490 chr14:75545685 A/G cg11812906 chr14:75593930 NEK9 0.75 14.11 0.61 6.23e-36 Height; LIHC cis rs2730245 1.000 rs2657365 chr7:158722753 A/T cg24397884 chr7:158709396 WDR60 -0.41 -6.35 -0.32 7.03e-10 Height; LIHC cis rs6088580 0.524 rs6088564 chr20:33249444 A/G cg08999081 chr20:33150536 PIGU -0.43 -7.24 -0.36 2.89e-12 Glomerular filtration rate (creatinine); LIHC cis rs3823572 0.564 rs2971973 chr7:133644256 G/A cg03336402 chr7:133662267 EXOC4 -0.47 -5.75 -0.3 1.93e-8 Intelligence (multi-trait analysis); LIHC cis rs2777491 0.915 rs16971767 chr15:41623308 T/C cg18705301 chr15:41695430 NDUFAF1 -0.59 -8.92 -0.43 2.86e-17 Ulcerative colitis; LIHC cis rs35110281 0.574 rs1836856 chr21:44964638 A/T cg04455712 chr21:45112962 RRP1B 0.41 6.79 0.34 5.1e-11 Mean corpuscular volume; LIHC cis rs9399137 0.507 rs6918512 chr6:135284839 T/G cg24558204 chr6:135376177 HBS1L 0.6 10.23 0.48 1.34e-21 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs1843834 0.505 rs3820763 chr2:225347270 A/G cg22509189 chr2:225307070 NA 0.82 11.67 0.53 1.04e-26 IgE levels in asthmatics (D.p. specific); LIHC cis rs172166 0.694 rs203884 chr6:28077374 G/T cg16479474 chr6:28041457 NA 0.36 6.17 0.32 1.95e-9 Cardiac Troponin-T levels; LIHC cis rs875971 1.000 rs1968225 chr7:65874773 T/C cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC trans rs4714291 0.802 rs2984430 chr6:39983741 A/G cg02267698 chr19:7991119 CTXN1 -0.38 -6.46 -0.33 3.66e-10 Strep throat; LIHC cis rs7085104 0.700 rs7096183 chr10:104609466 T/C cg15744005 chr10:104629667 AS3MT -0.4 -8.94 -0.44 2.4e-17 Immature fraction of reticulocytes;Schizophrenia; LIHC trans rs7613875 0.641 rs6446194 chr3:50067298 T/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.53 -0.33 2.38e-10 Body mass index; LIHC cis rs12479064 0.604 rs11893359 chr2:99954608 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.45 -6.29 -0.32 9.64e-10 Chronic sinus infection; LIHC cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.64 5.71 0.3 2.43e-8 Platelet count; LIHC cis rs11864453 0.713 rs2241412 chr16:72144284 A/G cg16558253 chr16:72132732 DHX38 -0.5 -8.22 -0.41 4.16e-15 Fibrinogen levels; LIHC cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC trans rs2797160 1.000 rs1935772 chr6:125994708 T/C cg05039488 chr6:79577232 IRAK1BP1 -0.45 -6.5 -0.33 2.76e-10 Endometrial cancer; LIHC cis rs11190604 1.000 rs12354411 chr10:102294537 G/A cg07080220 chr10:102295463 HIF1AN 0.55 8.07 0.4 1.17e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs507080 0.736 rs659564 chr11:118570914 C/A cg04173919 chr11:118528438 PHLDB1 0.33 6.16 0.32 2.06e-9 Serum metabolite levels; LIHC cis rs7843479 0.601 rs2002941 chr8:21834366 A/C cg17168535 chr8:21777572 XPO7 0.58 10.4 0.49 3.53e-22 Mean corpuscular volume; LIHC trans rs1973993 0.691 rs4000303 chr1:96913765 A/G cg10631902 chr5:14652156 NA 0.37 10.13 0.48 2.93e-21 Weight; LIHC cis rs17826219 0.561 rs4085382 chr17:29071202 T/C cg13385521 chr17:29058706 SUZ12P 0.8 8.26 0.41 3.16e-15 Body mass index; LIHC cis rs4755351 0.553 rs11032156 chr11:33158142 T/C cg05567920 chr11:33183001 CSTF3 0.43 6.26 0.32 1.17e-9 Lung cancer in ever smokers; LIHC cis rs1005277 0.505 rs10827835 chr10:38150709 G/A cg25427524 chr10:38739819 LOC399744 0.64 12.25 0.55 7.71e-29 Extrinsic epigenetic age acceleration; LIHC cis rs7103648 0.669 rs12577383 chr11:47774238 C/T cg20307385 chr11:47447363 PSMC3 0.98 15.78 0.65 1.63e-42 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs11212260 0.678 rs11212203 chr11:107267629 A/G cg25435332 chr11:107328525 CWF19L2 0.72 8.26 0.41 3.14e-15 IgG glycosylation; LIHC cis rs11971779 0.616 rs11771715 chr7:139027496 T/C cg07862535 chr7:139043722 LUC7L2 0.58 10.03 0.48 6.38e-21 Diisocyanate-induced asthma; LIHC cis rs9457247 1.000 rs422694 chr6:167406074 G/T cg23791538 chr6:167370224 RNASET2 -0.65 -11.13 -0.52 9.18e-25 Crohn's disease; LIHC cis rs9381040 0.655 rs7738684 chr6:41038552 G/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.39 -6.23 -0.32 1.38e-9 Alzheimer's disease (late onset); LIHC cis rs5758659 1.000 rs5758660 chr22:42623718 C/A cg19513890 chr22:42538836 CYP2D7P1 -0.39 -7.52 -0.38 4.81e-13 Cognitive function; LIHC cis rs17106184 1.000 rs17106235 chr1:50943370 C/G cg07174182 chr1:51127561 FAF1 -0.66 -7.21 -0.36 3.72e-12 Type 2 diabetes; LIHC cis rs12744310 0.945 rs12740093 chr1:41760001 C/T cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.72e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1215050 0.755 rs6851840 chr4:98776366 A/G cg05340658 chr4:99064831 C4orf37 0.39 5.9 0.3 8.9e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs1878931 0.582 rs40633 chr16:3425325 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.45 -0.42 8.74e-16 Body mass index (adult); LIHC cis rs56235845 0.694 rs12055081 chr5:176757191 C/T cg16006841 chr5:176797999 RGS14 0.57 7.59 0.38 3.13e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs5758511 0.514 rs5758586 chr22:42517471 A/T cg20195005 chr22:42527684 CYP2D6 0.32 6.15 0.32 2.19e-9 Birth weight; LIHC cis rs2286503 0.780 rs2240727 chr7:22852512 C/T cg11367502 chr7:22862612 TOMM7 0.47 8.08 0.4 1.12e-14 Fibrinogen; LIHC cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg22633049 chr21:46681294 NA -0.37 -6.32 -0.32 8.19e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5769765 0.908 rs138889 chr22:50226673 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -8.78 -0.43 7.7e-17 Schizophrenia; LIHC cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.27e-12 Bipolar disorder; LIHC cis rs2228479 0.557 rs34420680 chr16:89809171 C/T cg04013166 chr16:89971882 TCF25 0.49 6.04 0.31 4.01e-9 Skin colour saturation; LIHC cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg02353165 chr6:42928485 GNMT 0.98 16.41 0.66 4.89e-45 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs9916302 0.605 rs12938099 chr17:37612910 T/G cg07936489 chr17:37558343 FBXL20 -0.84 -12.09 -0.55 2.86e-28 Glomerular filtration rate (creatinine); LIHC cis rs6964587 0.867 rs12704637 chr7:91874686 C/T cg17063962 chr7:91808500 NA 0.99 15.28 0.64 1.49e-40 Breast cancer; LIHC cis rs921968 0.540 rs10190250 chr2:219457731 C/T cg02985541 chr2:219472218 PLCD4 -0.41 -6.57 -0.33 1.89e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs10876993 0.928 rs7136269 chr12:58075937 G/A cg04478727 chr12:58166393 METTL1;FAM119B -0.43 -6.05 -0.31 3.75e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg02503808 chr4:7069936 GRPEL1 0.78 11.35 0.52 1.55e-25 Monocyte percentage of white cells; LIHC cis rs2834256 0.961 rs7280640 chr21:35125078 C/G cg14850771 chr21:34775459 IFNGR2 0.38 5.71 0.3 2.43e-8 Red cell distribution width; LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg14671364 chr1:107599128 PRMT6 0.52 7.73 0.39 1.2e-13 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs782590 0.967 rs4290693 chr2:55799991 C/G cg18811423 chr2:55921094 PNPT1 0.92 15.21 0.64 2.96e-40 Metabolic syndrome; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg03604819 chr4:17813007 NCAPG;DCAF16 -0.44 -6.17 -0.32 1.96e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs4654899 1.000 rs72865329 chr1:21517567 G/A cg08539965 chr1:21396338 EIF4G3 0.34 6.02 0.31 4.48e-9 Superior frontal gyrus grey matter volume; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg27166718 chr6:118880109 PLN;C6orf204 -0.51 -6.21 -0.32 1.56e-9 Diastolic blood pressure; LIHC cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg10802521 chr3:52805072 NEK4 -0.44 -7.5 -0.38 5.67e-13 Bipolar disorder; LIHC cis rs7520050 0.778 rs3014218 chr1:46026328 A/C cg03146154 chr1:46216737 IPP -0.47 -7.6 -0.38 2.79e-13 Red blood cell count;Reticulocyte count; LIHC cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.12 11.35 0.52 1.52e-25 Platelet count; LIHC cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg02290350 chr8:58132656 NA 0.48 9.52 0.46 3.28e-19 Developmental language disorder (linguistic errors); LIHC trans rs459571 0.959 rs461462 chr9:136911272 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.5 -7.69 -0.38 1.63e-13 Platelet distribution width; LIHC cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg07424592 chr7:64974309 NA 0.81 9.49 0.46 4.1e-19 Diabetic kidney disease; LIHC cis rs367615 0.506 rs246102 chr5:108699695 C/G cg17395555 chr5:108820864 NA -0.29 -6.22 -0.32 1.49e-9 Colorectal cancer (SNP x SNP interaction); LIHC cis rs9486719 1.000 rs9373978 chr6:97056255 T/C cg06623918 chr6:96969491 KIAA0776 -0.74 -7.36 -0.37 1.35e-12 Migraine;Coronary artery disease; LIHC cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.8 12.63 0.56 2.78e-30 Total body bone mineral density; LIHC cis rs6089584 1.000 rs6089583 chr20:60563624 G/A cg12751644 chr20:60527061 NA -0.37 -6.09 -0.31 3.12e-9 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18504358 chr14:23340787 LRP10 0.47 6.89 0.35 2.64e-11 Pancreatic cancer; LIHC cis rs6545883 0.931 rs11125885 chr2:61755728 G/C cg15711740 chr2:61764176 XPO1 -0.44 -6.14 -0.32 2.27e-9 Tuberculosis; LIHC cis rs9916302 0.645 rs1053651 chr17:37822311 A/C cg00129232 chr17:37814104 STARD3 -0.56 -10.58 -0.5 7.91e-23 Glomerular filtration rate (creatinine); LIHC cis rs916888 0.610 rs199529 chr17:44837217 A/C cg15921436 chr17:44337874 NA 0.59 6.15 0.32 2.2e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg05368731 chr17:41323189 NBR1 0.73 12.58 0.56 4.43e-30 Menopause (age at onset); LIHC cis rs7193541 0.965 rs8050262 chr16:74661159 T/C cg01733217 chr16:74700730 RFWD3 0.54 10.37 0.49 4.27e-22 Multiple myeloma; LIHC cis rs4407350 0.837 rs5765710 chr22:44914354 C/T cg26276947 chr22:44892394 LDOC1L -0.32 -6.07 -0.31 3.47e-9 Intelligence (multi-trait analysis); LIHC cis rs10791097 0.694 rs7942621 chr11:130751308 C/G cg22079354 chr11:130786696 SNX19 0.43 6.18 0.32 1.82e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg09455208 chr3:40491958 NA 0.39 7.85 0.39 5.3e-14 Renal cell carcinoma; LIHC trans rs2727020 0.521 rs4980445 chr11:49570183 C/T cg18944383 chr4:111397179 ENPEP 0.35 8.09 0.4 1.05e-14 Coronary artery disease; LIHC cis rs3823572 0.564 rs10272270 chr7:133636174 A/T cg03336402 chr7:133662267 EXOC4 0.48 5.93 0.31 7.34e-9 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs13235972 chr7:65883605 C/T cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs9427116 0.502 rs9426827 chr1:154589965 T/C cg17218026 chr1:154582156 ADAR 0.36 7.04 0.36 1.07e-11 Blood protein levels; LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg14004847 chr7:1930337 MAD1L1 -0.48 -7.19 -0.36 4.23e-12 Bipolar disorder and schizophrenia; LIHC cis rs6088580 0.524 rs4911437 chr20:33266149 G/T cg08999081 chr20:33150536 PIGU -0.43 -7.18 -0.36 4.49e-12 Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg20607798 chr8:58055168 NA 0.66 8.38 0.41 1.43e-15 Developmental language disorder (linguistic errors); LIHC cis rs9303401 0.614 rs35308719 chr17:57163501 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 8.97 0.44 2e-17 Cognitive test performance; LIHC cis rs11098499 0.722 rs7673476 chr4:120248683 C/T cg09307838 chr4:120376055 NA 0.68 10.76 0.5 1.88e-23 Corneal astigmatism; LIHC cis rs34375054 0.724 rs4517581 chr12:125667394 A/G cg25124228 chr12:125621409 AACS -0.41 -6.66 -0.34 1.12e-10 Post bronchodilator FEV1/FVC ratio; LIHC cis rs3768617 0.811 rs12144261 chr1:183014148 A/G ch.1.3577855R chr1:183094577 LAMC1 0.47 7.46 0.37 7.01e-13 Fuchs's corneal dystrophy; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.97 -0.31 5.99e-9 Total body bone mineral density; LIHC cis rs2795502 0.873 rs1815716 chr10:43410200 G/A cg20628663 chr10:43360327 NA 0.45 6.7 0.34 8.53e-11 Blood protein levels; LIHC cis rs6809651 0.524 rs12638263 chr3:185795855 A/C cg00760338 chr3:185826511 ETV5 -0.78 -11.27 -0.52 2.86e-25 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; LIHC cis rs506338 0.517 rs12269736 chr11:64471986 T/C cg08800856 chr11:64428347 NRXN2 0.41 6.38 0.33 5.65e-10 Body mass index;Urate levels; LIHC cis rs1707322 0.963 rs4459051 chr1:46451203 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6088580 0.634 rs6058073 chr20:33116483 T/C cg08999081 chr20:33150536 PIGU 0.68 13.41 0.59 3.11e-33 Glomerular filtration rate (creatinine); LIHC cis rs9611519 0.828 rs9611460 chr22:41418297 T/C cg03806693 chr22:41940476 POLR3H -0.63 -6.8 -0.35 4.69e-11 Neuroticism; LIHC cis rs2404602 0.716 rs7174953 chr15:76906847 A/C cg03037974 chr15:76606532 NA 0.74 14.29 0.61 1.19e-36 Blood metabolite levels; LIHC cis rs769267 0.895 rs1858999 chr19:19497669 C/G cg26732615 chr19:19648335 CILP2;YJEFN3 -0.39 -5.93 -0.31 7.52e-9 Tonsillectomy; LIHC cis rs9303401 0.659 rs12946852 chr17:57013337 G/C cg25039879 chr17:56429692 SUPT4H1 0.79 8.95 0.44 2.37e-17 Cognitive test performance; LIHC cis rs743757 1.000 rs2073496 chr3:50431142 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 0.53 8.38 0.41 1.38e-15 Diastolic blood pressure; LIHC cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg14262678 chr6:151773367 RMND1;C6orf211 0.54 8.11 0.4 8.94e-15 Menarche (age at onset); LIHC cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg06466757 chr4:1255808 NA 0.34 5.82 0.3 1.32e-8 Obesity-related traits; LIHC cis rs2204008 0.837 rs12366727 chr12:38365748 A/C cg26384229 chr12:38710491 ALG10B 0.84 10.22 0.48 1.44e-21 Bladder cancer; LIHC cis rs7106204 0.748 rs6484031 chr11:24237115 A/C ch.11.24196551F chr11:24239977 NA 0.8 11.43 0.53 7.64e-26 Response to Homoharringtonine (cytotoxicity); LIHC cis rs9911578 1.000 rs7223955 chr17:56917053 C/A cg12560992 chr17:57184187 TRIM37 0.98 17.84 0.69 8.98e-51 Intelligence (multi-trait analysis); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09145019 chr1:17972199 ARHGEF10L 0.43 6.84 0.35 3.77e-11 Longevity; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19990785 chr11:67232403 TMEM134 0.44 6.57 0.33 1.93e-10 Lung function (FEV1/FVC); LIHC cis rs7772486 0.720 rs6931553 chr6:146112348 T/C cg13319975 chr6:146136371 FBXO30 0.39 6.34 0.32 7.29e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg01017244 chr2:74357527 NA 0.64 11.43 0.53 7.74e-26 Gestational age at birth (maternal effect); LIHC cis rs5769707 0.681 rs916360 chr22:50041972 T/C cg01652190 chr22:50026171 C22orf34 -0.35 -7.75 -0.39 1.09e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs1816752 0.805 rs4769353 chr13:25000456 A/G cg22771759 chr13:24902376 NA 0.32 6.68 0.34 9.65e-11 Obesity-related traits; LIHC cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs35110281 0.667 rs4819286 chr21:45120121 G/A cg21573476 chr21:45109991 RRP1B -0.53 -10.35 -0.49 5.29e-22 Mean corpuscular volume; LIHC cis rs250677 0.687 rs2963485 chr5:148452043 A/G cg18129178 chr5:148520854 ABLIM3 0.43 6.71 0.34 7.91e-11 Breast cancer; LIHC cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg14983838 chr19:29218262 NA 0.49 7.55 0.38 3.94e-13 Methadone dose in opioid dependence; LIHC cis rs6424115 0.767 rs11591202 chr1:24102080 A/C cg15997130 chr1:24165203 NA -0.38 -6.83 -0.35 3.82e-11 Immature fraction of reticulocytes; LIHC cis rs1534166 0.647 rs1464937 chr3:133536655 C/G cg12373951 chr3:133503437 NA -0.51 -7.24 -0.36 2.93e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs7412746 0.658 rs11204739 chr1:150865760 A/G cg18016565 chr1:150552671 MCL1 0.51 9.75 0.47 5.67e-20 Melanoma; LIHC cis rs1018836 0.631 rs9987164 chr8:91470910 T/G cg16814680 chr8:91681699 NA -0.36 -5.94 -0.31 7.19e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs600806 0.854 rs11102974 chr1:109886371 G/A cg16275483 chr1:110013120 SYPL2 -0.47 -5.86 -0.3 1.07e-8 Intelligence (multi-trait analysis); LIHC cis rs1538970 0.884 rs781226 chr1:45872662 T/C cg24296786 chr1:45957014 TESK2 0.52 7.66 0.38 1.88e-13 Platelet count; LIHC cis rs61677309 1.000 rs4938494 chr11:118150735 G/C cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs2228479 0.717 rs17233678 chr16:89809962 T/C cg06558623 chr16:89946397 TCF25 0.87 11.95 0.54 9.72e-28 Skin colour saturation; LIHC cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg13047869 chr3:10149882 C3orf24 -0.53 -6.76 -0.34 6.03e-11 Alzheimer's disease; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg06873352 chr17:61820015 STRADA 0.75 13.43 0.59 2.57e-33 Prudent dietary pattern; LIHC cis rs6456156 0.586 rs12527827 chr6:167469271 C/T cg07741184 chr6:167504864 NA 0.29 6.88 0.35 2.92e-11 Primary biliary cholangitis; LIHC cis rs1348850 0.567 rs4893838 chr2:178531436 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.58 7.67 0.38 1.84e-13 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg18357526 chr6:26021779 HIST1H4A -0.54 -6.5 -0.33 2.88e-10 Blood metabolite levels; LIHC cis rs1144333 1.000 rs5745354 chr1:76275178 G/A cg22875332 chr1:76189707 ACADM -0.41 -6.83 -0.35 4e-11 Attention function in attention deficit hyperactive disorder; LIHC cis rs12477438 0.834 rs6757019 chr2:99676936 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -10.53 -0.49 1.24e-22 Chronic sinus infection; LIHC cis rs1577917 1.000 rs10455456 chr6:86670322 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.53 -0.33 2.35e-10 Response to antipsychotic treatment; LIHC cis rs2050392 1.000 rs2050392 chr10:30691503 G/A cg25182066 chr10:30743637 MAP3K8 -0.44 -7.12 -0.36 6.39e-12 Inflammatory bowel disease; LIHC cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg25072359 chr17:41440525 NA 0.37 5.83 0.3 1.3e-8 Menopause (age at onset); LIHC cis rs9309473 1.000 rs10184268 chr2:73627044 C/T cg20560298 chr2:73613845 ALMS1 -0.58 -7.14 -0.36 5.59e-12 Metabolite levels; LIHC cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg14257396 chr1:107603778 NA 0.35 5.75 0.3 1.96e-8 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs34779708 0.966 rs10827491 chr10:35427395 G/A cg04310649 chr10:35416472 CREM -0.43 -5.86 -0.3 1.11e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs7100689 0.646 rs6585967 chr10:82139791 A/G cg00277334 chr10:82204260 NA 0.57 7.5 0.38 5.54e-13 Post bronchodilator FEV1; LIHC cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg12310025 chr6:25882481 NA -0.6 -8.51 -0.42 5.36e-16 Blood metabolite levels; LIHC trans rs6977660 0.770 rs10224061 chr7:19852619 C/G cg17424134 chr2:27616206 FTHL3;PPM1G 0.44 6.21 0.32 1.58e-9 Thyroid stimulating hormone; LIHC trans rs561341 1.000 rs555629 chr17:30294136 T/C cg20587970 chr11:113659929 NA -1.38 -11.72 -0.54 6.87e-27 Hip circumference adjusted for BMI; LIHC cis rs6933660 0.800 rs2046371 chr6:151754744 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.6 9.76 0.47 5.01e-20 Menarche (age at onset); LIHC cis rs6466055 0.796 rs9649275 chr7:104935801 T/G cg04380332 chr7:105027541 SRPK2 0.34 6.43 0.33 4.38e-10 Schizophrenia; LIHC cis rs1801251 1.000 rs13008942 chr2:233594875 G/A cg25237894 chr2:233734115 C2orf82 0.57 11.12 0.52 1.03e-24 Coronary artery disease; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.15 0.55 1.76e-28 Height; LIHC cis rs61440199 0.786 rs73818815 chr3:20148087 A/T cg00235661 chr3:20228976 SGOL1 -0.41 -5.82 -0.3 1.35e-8 Staphylococcus aureus nasal carriage (intermittent); LIHC cis rs992157 0.672 rs2382829 chr2:219184617 G/A cg00012203 chr2:219082015 ARPC2 0.76 10.74 0.5 2.16e-23 Colorectal cancer; LIHC cis rs11112613 0.713 rs12316204 chr12:105944244 G/A cg03607813 chr12:105948248 NA 0.66 12.86 0.57 3.71e-31 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.62 9.67 0.46 1.04e-19 Height; LIHC cis rs5769765 0.773 rs58375955 chr22:50312630 A/G cg02269571 chr22:50332266 NA -0.76 -9.95 -0.47 1.15e-20 Schizophrenia; LIHC cis rs6860806 0.507 rs272854 chr5:131688017 C/T cg24060327 chr5:131705240 SLC22A5 -0.78 -12.29 -0.55 5.07e-29 Breast cancer; LIHC cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.56 -0.46 2.35e-19 Bipolar disorder; LIHC cis rs1878931 0.543 rs1129568 chr16:3483475 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.95 20.04 0.73 1.27e-59 Body mass index (adult); LIHC cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg25894440 chr7:65020034 NA -0.55 -6.21 -0.32 1.51e-9 Diabetic kidney disease; LIHC cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.55 7.9 0.39 3.91e-14 Lymphocyte counts; LIHC cis rs240764 0.817 rs240113 chr6:101058886 G/A cg09795085 chr6:101329169 ASCC3 0.53 7.52 0.38 4.73e-13 Neuroticism; LIHC cis rs10504229 0.511 rs16921553 chr8:57979314 T/C cg02290350 chr8:58132656 NA 0.32 5.86 0.3 1.1e-8 Developmental language disorder (linguistic errors); LIHC cis rs240764 0.697 rs12189562 chr6:101168679 A/G cg09795085 chr6:101329169 ASCC3 -0.48 -6.64 -0.34 1.25e-10 Neuroticism; LIHC cis rs2050392 0.624 rs303435 chr10:30731491 T/C cg02070205 chr10:30722105 MAP3K8 -0.43 -5.79 -0.3 1.59e-8 Inflammatory bowel disease; LIHC cis rs2836950 0.565 rs2150413 chr21:40614878 C/T cg11890956 chr21:40555474 PSMG1 -0.45 -7.41 -0.37 9.69e-13 Menarche (age at onset); LIHC cis rs7572733 0.534 rs1589162 chr2:198782692 A/G cg10820045 chr2:198174542 NA 0.46 7.06 0.36 9.37e-12 Dermatomyositis; LIHC cis rs10751667 0.961 rs10794358 chr11:985547 C/T cg06064525 chr11:970664 AP2A2 -0.49 -12.17 -0.55 1.51e-28 Alzheimer's disease (late onset); LIHC cis rs2933343 0.621 rs4927921 chr3:128568868 A/G cg24203234 chr3:128598194 ACAD9 -0.41 -5.8 -0.3 1.51e-8 IgG glycosylation; LIHC cis rs1448094 0.512 rs12309296 chr12:86241566 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.3 0.32 9.06e-10 Major depressive disorder; LIHC cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg12463550 chr7:65579703 CRCP -0.67 -6.86 -0.35 3.29e-11 Diabetic kidney disease; LIHC cis rs1062753 0.771 rs932376 chr22:42614362 T/C cg00645731 chr22:42541494 CYP2D7P1 0.37 6.2 0.32 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels); LIHC cis rs2257205 0.667 rs9889631 chr17:56630359 G/T cg12560992 chr17:57184187 TRIM37 0.71 7.74 0.39 1.11e-13 Pancreatic cancer; LIHC cis rs2404602 0.684 rs62026898 chr15:76944371 C/A cg03037974 chr15:76606532 NA -0.61 -10.24 -0.48 1.21e-21 Blood metabolite levels; LIHC trans rs2727020 0.567 rs1164687 chr11:49290669 G/A cg18944383 chr4:111397179 ENPEP -0.28 -6.46 -0.33 3.62e-10 Coronary artery disease; LIHC cis rs459571 0.959 rs408307 chr9:136892523 A/G cg13789015 chr9:136890014 NCRNA00094 -0.44 -8.08 -0.4 1.13e-14 Platelet distribution width; LIHC cis rs4950322 0.512 rs4625342 chr1:146841602 G/C cg25205988 chr1:146714368 CHD1L 0.44 6.31 0.32 8.86e-10 Protein quantitative trait loci; LIHC cis rs17739167 0.550 rs6493014 chr15:42225008 A/G cg20935245 chr15:42234343 EHD4 -0.4 -7.34 -0.37 1.59e-12 Monocyte count; LIHC cis rs116095464 0.558 rs10475136 chr5:232796 A/G cg22857025 chr5:266934 NA -1.48 -17.96 -0.7 2.77e-51 Breast cancer; LIHC cis rs10876993 0.928 rs1689595 chr12:58056763 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.44 -0.33 3.94e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs4423214 0.592 rs1790349 chr11:71142350 A/G cg05163923 chr11:71159392 DHCR7 -0.54 -6.59 -0.34 1.67e-10 Vitamin D levels; LIHC cis rs2573652 0.723 rs2727201 chr15:100515311 A/G cg09918751 chr15:100517450 ADAMTS17 -0.9 -16.53 -0.67 1.64e-45 Height; LIHC cis rs763121 0.853 rs5750622 chr22:38956464 C/G cg06022373 chr22:39101656 GTPBP1 0.67 11.48 0.53 5.1e-26 Menopause (age at onset); LIHC trans rs2727020 0.675 rs1684258 chr11:49340020 G/A cg03929089 chr4:120376271 NA 0.67 9.31 0.45 1.64e-18 Coronary artery disease; LIHC cis rs2952156 0.883 rs2517960 chr17:37846521 T/C cg00129232 chr17:37814104 STARD3 -0.55 -10.32 -0.49 6.29e-22 Asthma; LIHC cis rs7264396 0.790 rs6058290 chr20:34247702 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -9.55 -0.46 2.51e-19 Total cholesterol levels; LIHC cis rs1555322 0.530 rs2425042 chr20:33865895 G/A cg07134254 chr20:33865797 NA 0.53 6.2 0.32 1.65e-9 Attention deficit hyperactivity disorder; LIHC cis rs4243830 0.850 rs57203351 chr1:6601319 T/C cg22792644 chr1:6614718 TAS1R1;NOL9 0.98 12.17 0.55 1.51e-28 Body mass index; LIHC cis rs7586673 0.930 rs6432667 chr2:161905001 T/C cg16506815 chr2:162101123 NA 0.49 7.91 0.39 3.63e-14 Intelligence (multi-trait analysis); LIHC cis rs1707322 0.686 rs3014239 chr1:46089801 G/A cg24296786 chr1:45957014 TESK2 0.42 6.16 0.32 2.07e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4073582 0.595 rs2508657 chr11:66043898 G/A cg16950941 chr11:66035639 RAB1B 0.6 8.99 0.44 1.73e-17 Gout; LIHC cis rs17292804 0.506 rs71417868 chr14:104046592 A/T cg19000871 chr14:103996768 TRMT61A -0.4 -6.64 -0.34 1.22e-10 Autism spectrum disorder or schizophrenia; LIHC cis rs4407350 0.870 rs135627 chr22:44906402 A/G cg04154583 chr22:44889756 LDOC1L 0.3 6.0 0.31 4.95e-9 Intelligence (multi-trait analysis); LIHC cis rs3540 0.574 rs2601205 chr15:90961813 A/G cg22089800 chr15:90895588 ZNF774 0.56 7.56 0.38 3.65e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs7772486 0.790 rs2247206 chr6:146216184 C/T cg05347473 chr6:146136440 FBXO30 0.35 5.71 0.3 2.43e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7937682 0.883 rs1611989 chr11:111456299 A/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.84 -0.51 1.02e-23 Primary sclerosing cholangitis; LIHC cis rs4908768 0.520 rs4908507 chr1:8738937 C/T cg20416874 chr1:8611966 RERE -0.6 -11.79 -0.54 3.85e-27 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2518564 0.507 rs856042 chr1:158986225 T/C cg11003133 chr1:159046391 AIM2 0.27 5.77 0.3 1.76e-8 White blood cell count; LIHC cis rs11190604 1.000 rs2495759 chr10:102320363 C/T cg07080220 chr10:102295463 HIF1AN 0.55 7.34 0.37 1.53e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7208859 0.573 rs58920731 chr17:29191746 G/T cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6442522 0.768 rs3821638 chr3:15511044 A/G cg16303742 chr3:15540471 COLQ 0.46 7.99 0.4 2.13e-14 Uric acid levels; LIHC cis rs929354 0.739 rs12533082 chr7:157014172 T/A cg17757837 chr7:157058334 UBE3C 0.74 11.93 0.54 1.14e-27 Body mass index; LIHC cis rs7312933 0.670 rs10880258 chr12:42547531 C/T cg01256987 chr12:42539512 GXYLT1 -0.41 -6.78 -0.34 5.35e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs9616064 0.506 rs11705341 chr22:47066294 T/C cg05621596 chr22:47072043 GRAMD4 -0.77 -11.97 -0.54 7.91e-28 Urate levels in obese individuals; LIHC cis rs1707322 1.000 rs10890350 chr1:46262378 G/A cg03146154 chr1:46216737 IPP 0.47 7.61 0.38 2.64e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2153535 0.505 rs1335629 chr6:8491863 C/T cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs644148 0.902 rs12982159 chr19:44964300 C/T cg15540054 chr19:45004280 ZNF180 -0.76 -11.22 -0.52 4.41e-25 Personality dimensions; LIHC cis rs1865760 1.000 rs9467636 chr6:25919549 A/C cg03264133 chr6:25882463 NA -0.38 -5.72 -0.3 2.35e-8 Height; LIHC cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg03452623 chr4:187889614 NA -0.32 -8.25 -0.41 3.55e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg13239077 chr3:184081208 POLR2H -0.48 -6.06 -0.31 3.57e-9 Hepatitis; LIHC cis rs12477438 0.520 rs13030961 chr2:99799520 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.91 14.24 0.61 1.92e-36 Chronic sinus infection; LIHC cis rs12744310 0.887 rs72665694 chr1:41775384 A/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs3796352 1.000 rs3796352 chr3:52913279 C/T cg07884673 chr3:53033167 SFMBT1 0.91 6.4 0.33 5.18e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs12579753 0.810 rs1343934 chr12:82123112 G/A cg07988820 chr12:82153109 PPFIA2 -0.49 -6.03 -0.31 4.14e-9 Resting heart rate; LIHC cis rs17095355 1.000 rs6584962 chr10:111689904 G/A cg00817464 chr10:111662876 XPNPEP1 -0.43 -6.36 -0.33 6.29e-10 Biliary atresia; LIHC cis rs716804 0.740 rs11042702 chr11:10287988 A/G cg01453529 chr11:10209919 SBF2 0.29 5.89 0.3 8.99e-9 Neuroticism; LIHC cis rs1046896 0.553 rs56775875 chr17:80831291 G/T cg02398342 chr17:80708632 TBCD;FN3K 0.41 6.25 0.32 1.2e-9 Glycated hemoglobin levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg01972394 chr1:19229528 ALDH4A1 0.44 6.28 0.32 1.03e-9 Lung function (FEV1/FVC); LIHC cis rs2228479 0.557 rs34420680 chr16:89809171 C/T cg19635926 chr16:89946313 TCF25 0.49 6.24 0.32 1.28e-9 Skin colour saturation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21819024 chr1:52344978 NRD1 0.41 6.3 0.32 9.25e-10 Cognitive function; LIHC cis rs7772486 0.754 rs9373475 chr6:146126419 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.34 -0.32 7.1e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11031096 0.782 rs4910904 chr11:4165529 C/T cg18678763 chr11:4115507 RRM1 0.52 7.96 0.4 2.55e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs8027181 0.839 rs998020 chr15:72999635 C/T cg25996835 chr15:72978165 BBS4;HIGD2B 0.5 7.63 0.38 2.35e-13 Triglyceride levels; LIHC cis rs7191439 0.790 rs2306046 chr16:88781419 A/G cg27087555 chr16:88793112 FAM38A -1.33 -12.61 -0.56 3.28e-30 Plateletcrit; LIHC cis rs11711311 1.000 rs9811353 chr3:113483979 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.23 0.45 2.97e-18 IgG glycosylation; LIHC cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs9549367 0.789 rs2287251 chr13:113889499 A/G cg18105134 chr13:113819100 PROZ -0.67 -11.68 -0.53 9.56e-27 Platelet distribution width; LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg03785755 chr6:26196794 NA 0.51 5.97 0.31 5.8e-9 Gout;Renal underexcretion gout; LIHC cis rs7584330 0.554 rs76408976 chr2:238384784 C/T cg08992911 chr2:238395768 MLPH 0.63 6.21 0.32 1.57e-9 Prostate cancer; LIHC cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg21782813 chr7:2030301 MAD1L1 0.43 7.49 0.38 6.07e-13 Bipolar disorder and schizophrenia; LIHC cis rs477895 0.713 rs882146 chr11:63976699 G/A cg04317338 chr11:64019027 PLCB3 0.85 10.34 0.49 5.35e-22 Mean platelet volume; LIHC cis rs597539 0.690 rs497149 chr11:68626639 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.72 10.62 0.5 5.7e-23 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.76 0.47 5.3e-20 Platelet count; LIHC cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs727505 1.000 rs7795943 chr7:124483796 C/A cg23710748 chr7:124431027 NA -0.32 -5.72 -0.3 2.37e-8 Lewy body disease; LIHC cis rs2075371 0.863 rs2075370 chr7:133967812 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.86 0.39 5.16e-14 Mean platelet volume; LIHC cis rs9325144 0.555 rs12424003 chr12:38688140 C/T cg26384229 chr12:38710491 ALG10B -0.57 -7.83 -0.39 6.04e-14 Morning vs. evening chronotype; LIHC cis rs763121 0.925 rs1056661 chr22:39080245 A/G cg06022373 chr22:39101656 GTPBP1 0.66 12.58 0.56 4.42e-30 Menopause (age at onset); LIHC cis rs2404602 0.735 rs62028423 chr15:76754514 G/A cg03037974 chr15:76606532 NA -0.64 -11.4 -0.52 1.01e-25 Blood metabolite levels; LIHC cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg23248424 chr5:179741104 GFPT2 -0.42 -6.32 -0.32 8.02e-10 Height; LIHC cis rs2071426 0.580 rs6583966 chr10:96759902 C/T cg09036531 chr10:96991505 NA -0.51 -6.07 -0.31 3.37e-9 Blood metabolite levels; LIHC cis rs2180341 1.000 rs9398837 chr6:127635217 G/A cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC trans rs208520 1.000 rs72880045 chr6:66965232 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.63 6.69 0.34 9.29e-11 Exhaled nitric oxide output; LIHC cis rs303806 1 rs303806 chr12:52166503 A/G cg07929700 chr12:52204284 NA -0.52 -5.89 -0.3 9.38e-9 Morning vs. evening chronotype; LIHC cis rs317689 0.690 rs547827 chr12:69669703 G/A cg22834771 chr12:69754056 YEATS4 -0.4 -6.04 -0.31 4.05e-9 Response to diuretic therapy; LIHC cis rs10985070 0.504 rs2296077 chr9:123944943 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 6.41 0.33 4.81e-10 Rheumatoid arthritis; LIHC cis rs7615952 0.673 rs9821905 chr3:125620850 A/G cg05084668 chr3:125655381 ALG1L 0.82 10.53 0.49 1.23e-22 Blood pressure (smoking interaction); LIHC cis rs2439831 0.867 rs2899082 chr15:43656043 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.93 17.36 0.68 7.38e-49 Lung cancer in ever smokers; LIHC cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg03806693 chr22:41940476 POLR3H 1.12 13.03 0.58 8.92e-32 Vitiligo; LIHC cis rs11718455 0.526 rs67553643 chr3:43928130 C/T cg08738300 chr3:44038990 NA 0.36 6.11 0.31 2.65e-9 Coronary artery disease; LIHC cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.12 11.68 0.53 9.41e-27 Platelet count; LIHC cis rs4423214 0.798 rs12224205 chr11:71180992 A/G cg05163923 chr11:71159392 DHCR7 -0.61 -8.22 -0.41 4.32e-15 Vitamin D levels; LIHC cis rs67311347 0.577 rs1880763 chr3:40283255 C/T cg00656387 chr3:40428638 ENTPD3 -0.42 -6.7 -0.34 8.51e-11 Renal cell carcinoma; LIHC cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.09 0.31 2.96e-9 Menopause (age at onset); LIHC cis rs1046896 0.739 rs28459016 chr17:80741194 G/A cg00809820 chr17:80708513 TBCD;FN3K 0.35 6.09 0.31 3.06e-9 Glycated hemoglobin levels; LIHC cis rs950169 0.922 rs11639244 chr15:84832650 G/A cg03959625 chr15:84868606 LOC388152 0.45 6.53 0.33 2.4e-10 Schizophrenia; LIHC cis rs372883 0.600 rs407712 chr21:30722531 G/A cg24692254 chr21:30365293 RNF160 -0.49 -6.19 -0.32 1.74e-9 Pancreatic cancer; LIHC cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg22105103 chr4:187893119 NA -0.33 -8.37 -0.41 1.48e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg02290350 chr8:58132656 NA 0.46 8.02 0.4 1.75e-14 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs4808199 0.739 rs2240117 chr19:19418916 C/T cg03709012 chr19:19516395 GATAD2A 0.87 11.02 0.51 2.34e-24 Nonalcoholic fatty liver disease; LIHC cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg08888203 chr3:10149979 C3orf24 0.56 6.39 0.33 5.32e-10 Alzheimer's disease; LIHC cis rs138777 0.927 rs1053593 chr22:35660875 G/T cg02285386 chr22:35695157 TOM1 0.34 5.72 0.3 2.38e-8 Cholesterol, total;Total cholesterol levels; LIHC cis rs6461049 0.638 rs1859993 chr7:2183702 A/G cg20295408 chr7:1910781 MAD1L1 -0.4 -5.96 -0.31 6.25e-9 Schizophrenia; LIHC cis rs34172651 0.517 rs7204288 chr16:24784531 A/G cg04756594 chr16:24857601 SLC5A11 0.57 8.6 0.42 2.89e-16 Intelligence (multi-trait analysis); LIHC trans rs2797160 0.967 rs2797162 chr6:126011381 G/T cg05039488 chr6:79577232 IRAK1BP1 0.46 6.52 0.33 2.57e-10 Endometrial cancer; LIHC cis rs5769707 0.706 rs763128 chr22:50018045 G/A cg01652190 chr22:50026171 C22orf34 -0.35 -7.82 -0.39 6.55e-14 Monocyte count;Monocyte percentage of white cells; LIHC trans rs8002861 0.840 rs1819596 chr13:44429554 A/G cg17145862 chr1:211918768 LPGAT1 0.58 10.75 0.5 2.1e-23 Leprosy; LIHC trans rs6489882 0.836 rs2384071 chr12:113367343 A/G cg10175203 chr3:128143634 NA 0.39 6.15 0.32 2.15e-9 Chronic lymphocytic leukemia; LIHC cis rs12188164 0.543 rs7728027 chr5:459943 T/C cg00049323 chr5:472564 LOC25845 0.35 5.85 0.3 1.14e-8 Cystic fibrosis severity; LIHC cis rs9814567 1.000 rs6763093 chr3:134254995 C/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs637571 0.510 rs10750772 chr11:65577427 C/T cg04055107 chr11:65626734 MUS81;CFL1 -0.46 -6.61 -0.34 1.5e-10 Eosinophil percentage of white cells; LIHC cis rs2991971 0.903 rs2991973 chr1:46020632 G/A cg24296786 chr1:45957014 TESK2 0.51 7.39 0.37 1.11e-12 High light scatter reticulocyte count; LIHC cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.66 0.34 1.1e-10 Diabetic kidney disease; LIHC cis rs17711722 0.653 rs2460421 chr7:65491123 A/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.38 -7.85 -0.39 5.34e-14 Calcium levels; LIHC cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg20607798 chr8:58055168 NA 0.73 8.47 0.42 7.17e-16 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg22800045 chr5:56110881 MAP3K1 0.7 8.78 0.43 8.1e-17 Initial pursuit acceleration; LIHC cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg12310025 chr6:25882481 NA -0.63 -8.89 -0.43 3.66e-17 Blood metabolite levels; LIHC cis rs9434723 0.841 rs9435152 chr1:9308249 C/T cg04199779 chr1:9294473 H6PD 0.58 6.02 0.31 4.38e-9 Height; LIHC cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg20684491 chr1:25596433 NA 0.28 5.81 0.3 1.46e-8 Erythrocyte sedimentation rate; LIHC cis rs2991971 1.000 rs2991971 chr1:46012748 C/G cg24296786 chr1:45957014 TESK2 0.51 7.32 0.37 1.75e-12 High light scatter reticulocyte count; LIHC cis rs57502260 0.834 rs3736228 chr11:68201295 A/G cg20283391 chr11:68216788 NA 0.48 5.99 0.31 5.23e-9 Total body bone mineral density (age 45-60); LIHC cis rs7020830 0.571 rs3780335 chr9:37376587 A/G cg14294708 chr9:37120828 ZCCHC7 -0.72 -8.73 -0.43 1.17e-16 Schizophrenia; LIHC cis rs10779751 1.000 rs6679878 chr1:11306882 A/G cg08854313 chr1:11322531 MTOR 0.82 11.65 0.53 1.17e-26 Body mass index; LIHC cis rs9902453 0.791 rs55655651 chr17:28244286 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.07e-27 Coffee consumption (cups per day); LIHC cis rs11122272 0.705 rs1416914 chr1:231533196 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -11.07 -0.51 1.46e-24 Hemoglobin concentration; LIHC cis rs5769707 0.616 rs135869 chr22:50008366 T/C cg01652190 chr22:50026171 C22orf34 -0.33 -7.39 -0.37 1.16e-12 Monocyte count;Monocyte percentage of white cells; LIHC trans rs561341 0.824 rs1978115 chr17:30220776 A/C cg20587970 chr11:113659929 NA -0.73 -8.32 -0.41 2.12e-15 Hip circumference adjusted for BMI; LIHC trans rs1005277 0.502 rs2800484 chr10:38542415 C/T cg04469686 chr1:162760199 HSD17B7 -0.39 -6.04 -0.31 4.12e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4908768 0.501 rs6668508 chr1:8574118 C/T cg20416874 chr1:8611966 RERE -0.68 -14.62 -0.62 6.36e-38 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs847649 0.842 rs869332 chr7:102632247 A/G cg18108683 chr7:102477205 FBXL13 -0.46 -7.22 -0.36 3.39e-12 Morning vs. evening chronotype; LIHC cis rs6754311 0.597 rs2278544 chr2:136546110 A/G cg15123519 chr2:136567270 LCT 0.39 7.27 0.37 2.46e-12 Mosquito bite size; LIHC cis rs10193935 0.901 rs17029411 chr2:42479149 G/A cg27598129 chr2:42591480 NA -0.69 -10.24 -0.48 1.25e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs4700695 0.719 rs27084 chr5:65435286 G/A cg21114390 chr5:65439923 SFRS12 -0.59 -8.6 -0.42 2.84e-16 Facial morphology (factor 19); LIHC cis rs881375 0.967 rs10739579 chr9:123694788 C/A cg14580859 chr9:123691850 NA 0.39 6.95 0.35 1.91e-11 Rheumatoid arthritis; LIHC cis rs7584330 0.554 rs80151891 chr2:238398826 G/T cg08992911 chr2:238395768 MLPH 0.58 6.07 0.31 3.43e-9 Prostate cancer; LIHC cis rs67478160 0.643 rs11626377 chr14:104234357 G/A cg24130564 chr14:104152367 KLC1 -0.34 -5.74 -0.3 2.1e-8 Schizophrenia; LIHC trans rs11722228 0.522 rs7681250 chr4:10133013 G/T cg26043149 chr18:55253948 FECH 0.96 14.75 0.62 1.96e-38 Gout;Urate levels;Serum uric acid levels; LIHC cis rs6964587 1.000 rs6952389 chr7:91657994 A/G cg17063962 chr7:91808500 NA 1.01 19.31 0.72 1.06e-56 Breast cancer; LIHC cis rs12477438 0.798 rs6542848 chr2:99573732 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.79 -10.2 -0.48 1.69e-21 Chronic sinus infection; LIHC cis rs600806 0.821 rs4970840 chr1:109873367 A/G cg16275483 chr1:110013120 SYPL2 -0.49 -6.11 -0.31 2.76e-9 Intelligence (multi-trait analysis); LIHC cis rs506338 0.517 rs530775 chr11:64426933 A/G cg27209729 chr11:64428925 NRXN2 0.34 6.39 0.33 5.32e-10 Body mass index;Urate levels; LIHC cis rs15676 0.783 rs10988120 chr9:131564695 G/C cg00228799 chr9:131580591 ENDOG -0.48 -6.8 -0.34 4.79e-11 Blood metabolite levels; LIHC cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg13397359 chr6:42928475 GNMT 0.47 6.59 0.34 1.63e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs763121 0.853 rs11704021 chr22:39074716 G/A cg14440974 chr22:39074834 NA -0.44 -7.09 -0.36 7.62e-12 Menopause (age at onset); LIHC cis rs4555082 0.874 rs28785556 chr14:105745388 A/T cg10792982 chr14:105748885 BRF1 0.52 6.74 0.34 6.79e-11 Mean platelet volume;Platelet distribution width; LIHC cis rs875971 0.867 rs1002053 chr7:65798545 G/A cg18876405 chr7:65276391 NA -0.37 -6.72 -0.34 7.79e-11 Aortic root size; LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg01238044 chr22:24384105 GSTT1 0.46 6.41 0.33 4.77e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10089 1.000 rs6595806 chr5:127499764 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.52 6.55 0.33 2.11e-10 Ileal carcinoids; LIHC cis rs4665809 1.000 rs6546727 chr2:26275282 C/T cg27170947 chr2:26402098 FAM59B -0.64 -8.06 -0.4 1.26e-14 Gut microbiome composition (summer); LIHC cis rs12477438 0.520 rs2516827 chr2:99772565 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.5 0.77 1.86e-69 Chronic sinus infection; LIHC cis rs4927850 0.958 rs1975582 chr3:195751439 G/T cg12923728 chr3:195709715 SDHAP1 -0.73 -10.5 -0.49 1.58e-22 Pancreatic cancer; LIHC cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg12379764 chr21:47803548 PCNT 0.61 9.02 0.44 1.33e-17 Testicular germ cell tumor; LIHC cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg22029157 chr1:209979665 IRF6 0.47 7.58 0.38 3.37e-13 Cleft lip with or without cleft palate; LIHC cis rs5769707 0.967 rs739248 chr22:50025205 T/C cg07959070 chr22:50026188 C22orf34 -0.33 -8.61 -0.42 2.67e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9522267 0.511 rs1163626 chr13:112225200 A/C cg10483660 chr13:112241077 NA -0.24 -6.36 -0.33 6.38e-10 Hepatitis; LIHC cis rs10744422 1.000 rs2061101 chr12:123348925 C/A cg18912006 chr12:123335444 HIP1R -0.65 -7.43 -0.37 9.02e-13 Schizophrenia; LIHC cis rs644799 1.000 rs1784135 chr11:95531748 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03228054 chr9:19049082 RRAGA 0.49 6.74 0.34 6.77e-11 Pancreatic cancer; LIHC cis rs7408868 0.908 rs757474 chr19:15273624 T/C cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC cis rs7107174 0.892 rs1007837 chr11:77941076 A/G cg02023728 chr11:77925099 USP35 0.44 8.39 0.41 1.3e-15 Testicular germ cell tumor; LIHC cis rs7107174 1.000 rs2512547 chr11:77960888 T/C cg02023728 chr11:77925099 USP35 0.48 9.06 0.44 1.03e-17 Testicular germ cell tumor; LIHC cis rs2439831 1.000 rs471229 chr15:43733994 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.61 8.7 0.43 1.4e-16 Lung cancer in ever smokers; LIHC cis rs943466 0.911 rs73746509 chr6:33729825 C/T cg25922239 chr6:33757077 LEMD2 -0.5 -6.14 -0.32 2.27e-9 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs10751667 0.666 rs7395182 chr11:927553 A/C cg06064525 chr11:970664 AP2A2 -0.55 -14.67 -0.62 3.89e-38 Alzheimer's disease (late onset); LIHC cis rs9457247 0.967 rs2757054 chr6:167380501 A/G cg23791538 chr6:167370224 RNASET2 0.69 11.76 0.54 4.7e-27 Crohn's disease; LIHC cis rs7552404 0.727 rs1159214 chr1:76317910 G/T cg03433033 chr1:76189801 ACADM -0.55 -6.92 -0.35 2.3e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9902453 0.934 rs7213902 chr17:28322935 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 11.31 0.52 2.14e-25 Coffee consumption (cups per day); LIHC cis rs1707322 0.686 rs2275085 chr1:46085852 C/T cg06784218 chr1:46089804 CCDC17 -0.42 -7.73 -0.39 1.21e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs67311347 0.910 rs7617361 chr3:40373259 G/T cg09455208 chr3:40491958 NA 0.33 6.44 0.33 4.1e-10 Renal cell carcinoma; LIHC cis rs72627123 0.867 rs74395411 chr14:74478584 T/C cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.95 0.31 6.57e-9 Morning vs. evening chronotype; LIHC cis rs7552404 1.000 rs11161521 chr1:76216330 T/C cg03433033 chr1:76189801 ACADM 0.66 9.27 0.45 2.12e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs11122272 0.735 rs10489610 chr1:231517765 C/A cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC trans rs1814175 0.616 rs1722020 chr11:49904189 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs10870270 1.000 rs10159943 chr10:133744744 T/C cg17892150 chr10:133769511 PPP2R2D -0.7 -13.06 -0.58 6.64e-32 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs477895 1.000 rs477895 chr11:64048912 C/T cg04317338 chr11:64019027 PLCB3 -0.54 -5.87 -0.3 1.04e-8 Mean platelet volume; LIHC cis rs11758351 0.588 rs2050948 chr6:26234952 A/G cg16070018 chr6:26224392 HIST1H3E 0.6 7.3 0.37 2.08e-12 Gout;Renal underexcretion gout; LIHC cis rs929354 1.000 rs1182391 chr7:157038368 T/C cg17757837 chr7:157058334 UBE3C -0.84 -14.18 -0.61 3.09e-36 Body mass index; LIHC cis rs4803468 0.967 rs4803461 chr19:41908871 G/A cg14132834 chr19:41945861 ATP5SL -0.43 -6.31 -0.32 8.43e-10 Height; LIHC cis rs35306767 0.903 rs12763396 chr10:927357 C/A cg20503657 chr10:835505 NA 1.03 12.12 0.55 2.33e-28 Eosinophil percentage of granulocytes; LIHC cis rs6860806 0.507 rs272892 chr5:131664349 C/T cg24060327 chr5:131705240 SLC22A5 -0.82 -12.81 -0.57 5.79e-31 Breast cancer; LIHC cis rs1862618 0.641 rs170733 chr5:56249251 A/G cg24531977 chr5:56204891 C5orf35 0.52 7.38 0.37 1.2e-12 Initial pursuit acceleration; LIHC cis rs7903847 0.620 rs61863815 chr10:99124389 A/G cg08345082 chr10:99160200 RRP12 -0.36 -5.96 -0.31 6.14e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6952407 1 rs6952407 chr7:66045512 A/G cg18876405 chr7:65276391 NA -0.48 -8.04 -0.4 1.5e-14 Cotinine glucuronidation; LIHC cis rs4629710 0.592 rs9492865 chr6:131534403 T/A cg12606694 chr6:131520996 AKAP7 0.58 6.84 0.35 3.77e-11 Multiple myeloma (IgH translocation); LIHC cis rs2642442 0.885 rs2642438 chr1:220970028 A/G cg04704887 chr1:220970030 MOSC1 -0.48 -6.1 -0.31 2.89e-9 Cholesterol, total;LDL cholesterol; LIHC cis rs7903847 0.642 rs10882923 chr10:99159018 G/A cg20016023 chr10:99160130 RRP12 -0.43 -6.81 -0.35 4.27e-11 Granulocyte percentage of myeloid white cells; LIHC cis rs2112347 0.502 rs34339 chr5:74931333 G/T cg19683494 chr5:74908142 NA -0.91 -11.57 -0.53 2.42e-26 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs7927771 1.000 rs12787330 chr11:47812311 C/T cg20135002 chr11:47629003 NA -0.54 -9.17 -0.44 4.7e-18 Subjective well-being; LIHC cis rs17685 0.725 rs6467993 chr7:75719350 G/A cg04610667 chr7:75704037 NA -0.33 -6.0 -0.31 5.08e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs801193 1.000 rs10274773 chr7:66133578 G/A cg26939375 chr7:64535504 NA -0.43 -6.8 -0.35 4.57e-11 Aortic root size; LIHC cis rs922107 0.817 rs528433 chr1:89987940 A/G cg15422784 chr1:90023713 LRRC8B -0.47 -7.22 -0.36 3.36e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs921968 0.643 rs532475 chr2:219434208 C/T cg17980119 chr2:219472607 PLCD4 0.33 5.75 0.3 1.93e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs10979 1.000 rs9496673 chr6:143885393 C/G cg25407410 chr6:143891975 LOC285740 -0.37 -6.01 -0.31 4.66e-9 Hypospadias; LIHC cis rs919433 0.963 rs1896857 chr2:198164530 A/G cg03934865 chr2:198174659 NA -0.59 -9.54 -0.46 2.77e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6545883 0.929 rs12617911 chr2:61740825 A/G cg14146966 chr2:61757674 XPO1 0.49 8.82 0.43 5.82e-17 Tuberculosis; LIHC cis rs12286929 0.617 rs12800807 chr11:115101353 T/C cg04055981 chr11:115044050 NA 0.43 6.24 0.32 1.27e-9 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs9902453 0.845 rs3102556 chr17:28042542 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.73 0.54 5.99e-27 Coffee consumption (cups per day); LIHC trans rs10411161 0.580 rs3848561 chr19:52379623 C/T cg22319618 chr22:45562946 NUP50 -0.51 -7.57 -0.38 3.56e-13 Breast cancer; LIHC cis rs3814231 0.531 rs12773054 chr10:115476042 C/T cg24846397 chr10:115438155 CASP7 -0.41 -6.83 -0.35 3.83e-11 Vitiligo; LIHC cis rs7589728 0.925 rs80065975 chr2:88502758 G/A cg04511125 chr2:88470314 THNSL2 0.88 8.5 0.42 6.12e-16 Plasma clusterin levels; LIHC cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.41 0.52 9.38e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs17401966 0.931 rs11584023 chr1:10302596 A/G cg15208524 chr1:10270712 KIF1B 0.4 6.08 0.31 3.22e-9 Hepatocellular carcinoma; LIHC cis rs11792861 0.888 rs57314245 chr9:111813832 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.78 0.43 8.02e-17 Menarche (age at onset); LIHC cis rs2279817 1.000 rs2279815 chr1:18022066 G/T cg21791023 chr1:18019539 ARHGEF10L 0.65 8.8 0.43 6.78e-17 Neuroticism; LIHC cis rs9902453 0.934 rs34433787 chr17:28496780 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.6 9.32 0.45 1.47e-18 Coffee consumption (cups per day); LIHC cis rs35306767 0.761 rs34480046 chr10:1027440 A/G cg26597838 chr10:835615 NA 0.91 8.21 0.41 4.74e-15 Eosinophil percentage of granulocytes; LIHC cis rs1419980 0.730 rs73260715 chr12:7781252 G/A cg10578777 chr12:7781093 NA -0.4 -5.83 -0.3 1.26e-8 HDL cholesterol levels; LIHC cis rs6952808 0.691 rs2398709 chr7:2112548 C/T cg04267008 chr7:1944627 MAD1L1 -0.52 -8.12 -0.4 8.38e-15 Bipolar disorder and schizophrenia; LIHC trans rs11098499 0.909 rs73842633 chr4:120375464 G/A cg25214090 chr10:38739885 LOC399744 0.59 9.48 0.46 4.57e-19 Corneal astigmatism; LIHC cis rs6570726 0.935 rs446242 chr6:145843866 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.65 0.46 1.25e-19 Lobe attachment (rater-scored or self-reported); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01032946 chr16:30991033 SETD1A 0.44 6.07 0.31 3.45e-9 Longevity; LIHC cis rs7903847 0.619 rs10882912 chr10:99138077 C/T cg06359132 chr10:99160096 RRP12 -0.41 -6.23 -0.32 1.35e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs8044868 0.530 rs8059437 chr16:72116467 A/G cg16558253 chr16:72132732 DHX38 -0.37 -6.38 -0.33 5.72e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC trans rs1005277 0.505 rs1208689 chr10:38097775 C/G cg23533926 chr12:111358616 MYL2 -0.33 -6.49 -0.33 3.06e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9733 0.621 rs12746899 chr1:150579678 A/T cg18016565 chr1:150552671 MCL1 -0.54 -11.08 -0.51 1.36e-24 Tonsillectomy; LIHC trans rs2832191 0.716 rs1888440 chr21:30454484 C/T cg14791747 chr16:20752902 THUMPD1 -0.47 -6.5 -0.33 2.92e-10 Dental caries; LIHC cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.75 0.47 5.42e-20 Mean platelet volume; LIHC cis rs11630290 0.639 rs6494442 chr15:64166891 A/G cg12036633 chr15:63758958 NA 0.57 5.96 0.31 6.35e-9 Iris characteristics; LIHC cis rs12701220 0.690 rs10243973 chr7:1064983 T/C cg26769984 chr7:1090371 C7orf50 0.56 7.26 0.37 2.57e-12 Bronchopulmonary dysplasia; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs5769765 0.542 rs738707 chr22:50250827 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.57 5.79 0.3 1.62e-8 Schizophrenia; LIHC cis rs8062405 1.000 rs56404918 chr16:28846840 T/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs7249142 0.512 rs12981160 chr19:19298099 T/A cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.4 -6.7 -0.34 8.69e-11 IgG glycosylation; LIHC cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg12463550 chr7:65579703 CRCP 0.67 6.86 0.35 3.29e-11 Diabetic kidney disease; LIHC cis rs11018874 0.709 rs10765241 chr11:89849316 T/C cg05041596 chr11:89867385 NAALAD2 0.41 6.37 0.33 5.92e-10 White blood cell types; LIHC cis rs801193 1.000 rs2659912 chr7:66157999 G/C cg14393609 chr7:65229607 NA 0.38 5.87 0.3 1.02e-8 Aortic root size; LIHC cis rs10751667 0.643 rs7396046 chr11:937176 T/C ch.11.42038R chr11:967971 AP2A2 0.55 10.04 0.48 5.67e-21 Alzheimer's disease (late onset); LIHC cis rs9549367 0.737 rs9549712 chr13:113902355 G/A cg00898013 chr13:113819073 PROZ -0.42 -7.18 -0.36 4.24e-12 Platelet distribution width; LIHC cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg25894440 chr7:65020034 NA -0.56 -6.47 -0.33 3.37e-10 Diabetic kidney disease; LIHC trans rs61931739 0.534 rs35056575 chr12:34142914 A/T cg26384229 chr12:38710491 ALG10B 0.58 7.33 0.37 1.64e-12 Morning vs. evening chronotype; LIHC trans rs2243480 1.000 rs160648 chr7:65543384 C/A cg10756647 chr7:56101905 PSPH 1.06 12.78 0.57 7.55e-31 Diabetic kidney disease; LIHC cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg18306943 chr3:40428807 ENTPD3 0.36 6.11 0.31 2.77e-9 Renal cell carcinoma; LIHC cis rs7677751 0.806 rs6836215 chr4:55102741 T/C cg17187183 chr4:55093834 PDGFRA 0.67 8.61 0.42 2.8e-16 Corneal astigmatism; LIHC cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg05590025 chr7:65112418 INTS4L2 -0.63 -6.98 -0.35 1.53e-11 Diabetic kidney disease; LIHC cis rs6502050 0.835 rs3935128 chr17:80113414 T/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs9814567 0.752 rs4955544 chr3:134332776 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg18404041 chr3:52824283 ITIH1 -0.55 -8.91 -0.43 3.01e-17 Bipolar disorder; LIHC cis rs7937682 0.961 rs552387 chr11:111490047 T/G cg09085632 chr11:111637200 PPP2R1B -0.89 -10.69 -0.5 3.2e-23 Primary sclerosing cholangitis; LIHC trans rs11098499 0.570 rs6832740 chr4:120546136 T/C cg25214090 chr10:38739885 LOC399744 0.5 8.07 0.4 1.24e-14 Corneal astigmatism; LIHC cis rs12744310 1.000 rs12025254 chr1:41756906 A/G cg03962019 chr1:41807865 NA 0.38 6.19 0.32 1.73e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs910316 1.000 rs2300601 chr14:75639571 A/G cg11812906 chr14:75593930 NEK9 0.66 12.06 0.55 3.93e-28 Height; LIHC cis rs6088590 0.550 rs12624640 chr20:32952125 G/A cg08999081 chr20:33150536 PIGU 0.54 8.51 0.42 5.58e-16 Coronary artery disease; LIHC cis rs17401966 0.931 rs746881 chr1:10346810 C/T cg15208524 chr1:10270712 KIF1B -0.38 -5.82 -0.3 1.38e-8 Hepatocellular carcinoma; LIHC cis rs4631830 0.695 rs11004584 chr10:51500088 G/T cg20129853 chr10:51489980 NA -0.39 -8.52 -0.42 5.04e-16 Prostate-specific antigen levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg18716194 chr12:110872950 ARPC3 0.52 6.97 0.35 1.64e-11 Systolic blood pressure; LIHC cis rs57590327 0.503 rs9866374 chr3:81615311 T/C cg07356753 chr3:81810745 GBE1 -0.55 -8.41 -0.41 1.09e-15 Extraversion; LIHC cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Bipolar disorder; LIHC cis rs7503168 0.818 rs9902765 chr17:33913143 A/G cg20932281 chr17:33905541 PEX12 0.56 7.25 0.37 2.79e-12 Plateletcrit; LIHC cis rs9287719 0.674 rs6432130 chr2:10821557 T/C cg02829992 chr2:10710499 NA 0.39 6.01 0.31 4.73e-9 Prostate cancer; LIHC cis rs13096760 1 rs13096760 chr3:49476806 T/C cg03060546 chr3:49711283 APEH 0.63 10.41 0.49 3.16e-22 Intelligence (multi-trait analysis); LIHC cis rs11098499 0.863 rs10030660 chr4:120436704 G/A cg09307838 chr4:120376055 NA 0.77 11.69 0.53 8.39e-27 Corneal astigmatism; LIHC cis rs4237845 0.537 rs4237844 chr12:58267987 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.57 -7.79 -0.39 8.15e-14 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg12463550 chr7:65579703 CRCP 0.69 7.15 0.36 5.29e-12 Diabetic kidney disease; LIHC cis rs9911578 0.835 rs10853006 chr17:56489076 G/A cg12560992 chr17:57184187 TRIM37 -0.89 -14.89 -0.63 5.13e-39 Intelligence (multi-trait analysis); LIHC cis rs644799 0.896 rs4430471 chr11:95646774 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.64 8.82 0.43 6.01e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs78456975 1.000 rs13413356 chr2:1553849 G/T cg01028140 chr2:1542097 TPO -0.53 -6.34 -0.32 7.32e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs6942756 0.806 rs2566886 chr7:128917866 G/A cg02491457 chr7:128862824 NA 0.57 8.59 0.42 3.23e-16 White matter hyperintensity burden; LIHC cis rs17253792 0.822 rs75560658 chr14:56079896 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs17685 0.753 rs8200 chr7:75696606 C/G cg01364799 chr7:75623366 TMEM120A 0.49 7.36 0.37 1.36e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7903847 0.642 rs11189204 chr10:99164394 C/T cg06359132 chr10:99160096 RRP12 -0.37 -5.93 -0.31 7.28e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg02931644 chr1:25747376 RHCE 0.35 7.65 0.38 2.06e-13 Erythrocyte sedimentation rate; LIHC cis rs7727544 0.735 rs273913 chr5:131661156 A/G cg24060327 chr5:131705240 SLC22A5 -0.61 -9.0 -0.44 1.59e-17 Blood metabolite levels; LIHC cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 9.88 0.47 2e-20 Platelet count; LIHC cis rs11690935 0.595 rs788171 chr2:172921832 A/G cg13550731 chr2:172543902 DYNC1I2 0.55 9.46 0.46 5.14e-19 Schizophrenia; LIHC cis rs12908161 1.000 rs12905057 chr15:85210765 A/G cg12863693 chr15:85201151 NMB 0.49 6.9 0.35 2.46e-11 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23959187 chr17:46102881 NA 0.46 6.68 0.34 9.5e-11 Pancreatic cancer; LIHC trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg18110333 chr6:292329 DUSP22 -0.58 -8.04 -0.4 1.44e-14 Menopause (age at onset); LIHC cis rs787274 1.000 rs2645993 chr9:115536267 T/A cg13803584 chr9:115635662 SNX30 -0.56 -6.25 -0.32 1.21e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg12792011 chr19:58661915 ZNF329 0.96 7.78 0.39 8.58e-14 Cholesterol, total; LIHC cis rs9527 0.518 rs7899608 chr10:104727304 C/T cg15744005 chr10:104629667 AS3MT -0.43 -5.83 -0.3 1.26e-8 Arsenic metabolism; LIHC cis rs1707322 1.000 rs12077974 chr1:46384141 G/A cg03146154 chr1:46216737 IPP 0.45 7.1 0.36 7.41e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2758596 0.850 rs2495270 chr1:156181530 A/G cg25208724 chr1:156163844 SLC25A44 0.73 8.22 0.41 4.41e-15 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs4819052 1.000 rs2297284 chr21:46705345 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 10.77 0.5 1.68e-23 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg05665937 chr4:1216051 CTBP1 0.44 5.81 0.3 1.44e-8 Obesity-related traits; LIHC cis rs7666738 0.791 rs10856934 chr4:99010844 A/G cg05340658 chr4:99064831 C4orf37 -0.73 -13.36 -0.59 4.6e-33 Colonoscopy-negative controls vs population controls; LIHC cis rs9916302 0.800 rs11869259 chr17:37518141 C/A cg03013999 chr17:37608204 MED1 -0.35 -5.93 -0.31 7.41e-9 Glomerular filtration rate (creatinine); LIHC cis rs11758351 0.778 rs41266801 chr6:26197493 C/A cg16070018 chr6:26224392 HIST1H3E 0.57 6.81 0.35 4.32e-11 Gout;Renal underexcretion gout; LIHC cis rs1691799 0.899 rs1168306 chr12:66738900 A/G cg16791601 chr12:66731901 HELB -0.57 -13.85 -0.6 6.11e-35 White blood cell count (basophil); LIHC cis rs12142240 0.660 rs72890715 chr1:46852077 A/G cg00530320 chr1:46809349 NSUN4 0.53 5.77 0.3 1.82e-8 Menopause (age at onset); LIHC cis rs244293 0.965 rs2628320 chr17:53207993 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.41 -0.37 1.01e-12 Menarche (age at onset); LIHC cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg12756686 chr19:29218302 NA 0.44 6.85 0.35 3.35e-11 Methadone dose in opioid dependence; LIHC cis rs2153535 0.580 rs9406171 chr6:8515362 T/C cg21535247 chr6:8435926 SLC35B3 0.63 8.29 0.41 2.68e-15 Motion sickness; LIHC cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg18252515 chr7:66147081 NA -1.26 -17.06 -0.68 1.15e-47 Diabetic kidney disease; LIHC cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg12310025 chr6:25882481 NA -0.63 -8.89 -0.43 3.66e-17 Blood metabolite levels; LIHC cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg05368731 chr17:41323189 NBR1 0.73 12.57 0.56 4.64e-30 Menopause (age at onset); LIHC cis rs6964587 1.000 rs2157747 chr7:91750578 A/G cg17063962 chr7:91808500 NA 1.01 19.45 0.72 2.9e-57 Breast cancer; LIHC cis rs13161895 0.877 rs75654641 chr5:179486021 C/T cg02702477 chr5:179499311 RNF130 0.89 11.71 0.53 7.5e-27 LDL cholesterol; LIHC trans rs2211698 0.536 rs78921201 chr21:35832276 C/T cg18044562 chr7:50468399 IKZF1 0.52 7.39 0.37 1.15e-12 Cancer; LIHC cis rs7000551 0.779 rs2443507 chr8:22373231 G/A cg12081754 chr8:22256438 SLC39A14 0.43 6.8 0.35 4.72e-11 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs4660261 0.526 rs2906458 chr1:44336389 A/G cg12908607 chr1:44402522 ARTN 0.51 8.54 0.42 4.36e-16 Intelligence (multi-trait analysis); LIHC trans rs7714584 1.000 rs11739619 chr5:150264662 A/T cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs12477438 0.834 rs1563108 chr2:99701153 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.15 -0.48 2.57e-21 Chronic sinus infection; LIHC cis rs4474465 0.688 rs7940720 chr11:78276674 C/T cg02023728 chr11:77925099 USP35 -0.33 -5.86 -0.3 1.09e-8 Alzheimer's disease (survival time); LIHC cis rs7847628 0.566 rs10739575 chr9:123606101 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.66 -8.88 -0.43 3.81e-17 Birth weight; LIHC cis rs2637266 0.783 rs846627 chr10:78539556 A/G cg18941641 chr10:78392320 NA 0.27 5.77 0.3 1.8e-8 Pulmonary function; LIHC cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.13 -0.31 2.37e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg06873352 chr17:61820015 STRADA 0.57 8.78 0.43 7.98e-17 Height; LIHC cis rs9379850 0.528 rs67575965 chr6:26196593 A/G cg16070018 chr6:26224392 HIST1H3E 0.49 6.55 0.33 2.15e-10 Intelligence (multi-trait analysis); LIHC cis rs600806 0.778 rs11101960 chr1:110008778 C/T cg11161837 chr1:110010384 SYPL2 0.45 6.14 0.31 2.32e-9 Intelligence (multi-trait analysis); LIHC trans rs5756813 0.688 rs5995498 chr22:38196573 T/G cg19894588 chr14:64061835 NA -0.68 -10.07 -0.48 4.52e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs4819052 0.851 rs4819040 chr21:46659762 T/C cg11663144 chr21:46675770 NA -0.31 -5.92 -0.31 7.71e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12893668 0.572 rs4900590 chr14:104146421 C/T cg24130564 chr14:104152367 KLC1 -0.55 -9.43 -0.45 6.56e-19 Reticulocyte count; LIHC cis rs2153535 0.580 rs2327050 chr6:8440630 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs7772486 0.875 rs2814866 chr6:146339414 C/A cg23711669 chr6:146136114 FBXO30 0.6 10.53 0.49 1.23e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs8062405 0.929 rs11150609 chr16:28870596 A/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs13161895 1.000 rs3719 chr5:179435118 T/C cg06664874 chr5:179499304 RNF130 -0.58 -7.13 -0.36 5.93e-12 LDL cholesterol; LIHC cis rs10876993 0.890 rs12302350 chr12:58062589 T/G cg18357645 chr12:58087776 OS9 0.53 8.79 0.43 7.4e-17 Celiac disease or Rheumatoid arthritis; LIHC cis rs875971 1.000 rs6961990 chr7:65888570 C/A cg11764359 chr7:65958608 NA 0.91 17.08 0.68 9.57e-48 Aortic root size; LIHC cis rs644799 1.000 rs693364 chr11:95621926 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 15.79 0.65 1.39e-42 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs35110281 0.744 rs162396 chr21:44947807 T/C cg04455712 chr21:45112962 RRP1B 0.44 7.32 0.37 1.79e-12 Mean corpuscular volume; LIHC cis rs2842992 0.789 rs9364536 chr6:160225559 G/C cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.68 0.57 1.82e-30 Age-related macular degeneration (geographic atrophy); LIHC cis rs716804 0.621 rs11042602 chr11:10078104 T/A cg01453529 chr11:10209919 SBF2 -0.3 -5.72 -0.3 2.37e-8 Neuroticism; LIHC cis rs921968 0.565 rs586194 chr2:219610433 A/G cg02985541 chr2:219472218 PLCD4 -0.38 -6.55 -0.33 2.09e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs2230307 0.536 rs526128 chr1:100473427 T/A cg24955406 chr1:100503596 HIAT1 0.62 6.2 0.32 1.62e-9 Carotid intima media thickness; LIHC cis rs7474896 0.583 rs7071147 chr10:38003376 T/C cg25427524 chr10:38739819 LOC399744 -0.5 -7.33 -0.37 1.63e-12 Obesity (extreme); LIHC cis rs7116495 0.609 rs2155145 chr11:71719619 G/T cg26138937 chr11:71823887 C11orf51 -1.32 -10.9 -0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs7726839 0.540 rs12520279 chr5:657291 T/C cg09021430 chr5:549028 NA -0.42 -8.57 -0.42 3.6e-16 Obesity-related traits; LIHC cis rs7945718 0.592 rs10765985 chr11:12676468 G/A cg25843174 chr11:12811716 TEAD1 0.33 7.71 0.38 1.42e-13 Educational attainment (years of education); LIHC cis rs7726839 0.540 rs72703078 chr5:594987 A/C cg09021430 chr5:549028 NA -0.42 -8.36 -0.41 1.65e-15 Obesity-related traits; LIHC cis rs7940866 0.834 rs7939417 chr11:130853832 T/A cg12179176 chr11:130786555 SNX19 0.62 9.05 0.44 1.07e-17 Schizophrenia; LIHC cis rs332507 0.519 rs13087350 chr3:124352085 C/T cg05980111 chr3:124395277 KALRN -0.3 -5.82 -0.3 1.39e-8 Plateletcrit; LIHC cis rs12960505 0.506 rs66882949 chr18:51048812 A/G cg24270629 chr18:50823537 DCC -0.47 -6.37 -0.33 6.22e-10 Intelligence (multi-trait analysis); LIHC cis rs11758351 0.925 rs2183948 chr6:26180332 A/G cg03854865 chr6:26224070 HIST1H3E 0.65 7.17 0.36 4.58e-12 Gout;Renal underexcretion gout; LIHC cis rs5758511 0.680 rs5758686 chr22:42655377 G/T cg00645731 chr22:42541494 CYP2D7P1 0.53 8.38 0.41 1.4e-15 Birth weight; LIHC cis rs12042938 0.507 rs1655301 chr1:231731730 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.58 -7.76 -0.39 9.66e-14 Neuranatomic and neurocognitive phenotypes; LIHC cis rs4407350 0.870 rs5765716 chr22:44915251 T/C cg26276947 chr22:44892394 LDOC1L 0.34 6.39 0.33 5.35e-10 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs6754311 0.509 rs10188066 chr2:136539513 G/A cg15123519 chr2:136567270 LCT 0.35 6.59 0.34 1.66e-10 Mosquito bite size; LIHC cis rs4589502 1.000 rs79390908 chr15:67130924 C/T cg09911534 chr15:67153556 NA -0.49 -5.99 -0.31 5.17e-9 Lung cancer (smoking interaction); LIHC cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg06640241 chr16:89574553 SPG7 -0.71 -12.1 -0.55 2.59e-28 Multiple myeloma (IgH translocation); LIHC cis rs2839186 0.721 rs3788252 chr21:47661235 C/T cg13012494 chr21:47604986 C21orf56 0.41 6.25 0.32 1.24e-9 Testicular germ cell tumor; LIHC cis rs7412746 0.611 rs11204747 chr1:150927152 A/G cg17724175 chr1:150552817 MCL1 -0.37 -7.45 -0.37 7.9e-13 Melanoma; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs60871478 0.645 rs111968669 chr7:856683 C/T cg00934597 chr7:893267 UNC84A -0.51 -5.99 -0.31 5.24e-9 Cerebrospinal P-tau181p levels; LIHC cis rs2576037 0.526 rs9304340 chr18:44526582 G/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -6.99 -0.35 1.44e-11 Personality dimensions; LIHC trans rs1814175 0.935 rs7482690 chr11:49648814 C/T cg03929089 chr4:120376271 NA -0.89 -17.5 -0.69 2e-49 Height; LIHC cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg12016809 chr21:47604291 C21orf56 0.43 6.25 0.32 1.21e-9 Testicular germ cell tumor; LIHC cis rs4833079 0.562 rs11944291 chr4:38631620 T/G cg18361445 chr4:38666374 KLF3;FLJ13197 0.53 7.53 0.38 4.59e-13 Body mass index; LIHC cis rs2153535 0.563 rs4428546 chr6:8490376 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs2180341 0.920 rs9398836 chr6:127576497 T/G cg24812749 chr6:127587940 RNF146 0.97 15.07 0.63 1.01e-39 Breast cancer; LIHC cis rs10078 0.571 rs890977 chr5:476910 T/C cg26072250 chr5:443457 EXOC3;C5orf55 0.76 10.09 0.48 3.94e-21 Fat distribution (HIV); LIHC cis rs7833790 1.000 rs7833384 chr8:82730915 T/C cg17211192 chr8:82754475 SNX16 -0.67 -12.1 -0.55 2.72e-28 Diastolic blood pressure; LIHC cis rs4718428 0.705 rs4718422 chr7:66359269 A/G cg18252515 chr7:66147081 NA -0.68 -9.28 -0.45 1.97e-18 Corneal structure; LIHC cis rs9902453 0.838 rs9646437 chr17:28209065 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.69 11.04 0.51 1.98e-24 Coffee consumption (cups per day); LIHC cis rs2806561 0.734 rs2806564 chr1:23506685 T/C cg19743168 chr1:23544995 NA 0.34 5.82 0.3 1.33e-8 Height; LIHC cis rs2404602 1.000 rs2404740 chr15:76852143 C/T cg23625390 chr15:77176239 SCAPER 0.43 7.23 0.36 3.27e-12 Blood metabolite levels; LIHC cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg05665937 chr4:1216051 CTBP1 0.43 5.73 0.3 2.26e-8 Obesity-related traits; LIHC cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.95 0.31 6.65e-9 Menopause (age at onset); LIHC cis rs477692 1.000 rs569235 chr10:131411620 T/C cg05714579 chr10:131428358 MGMT 0.46 7.55 0.38 3.89e-13 Response to temozolomide; LIHC cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg03264133 chr6:25882463 NA -0.42 -6.52 -0.33 2.5e-10 Height; LIHC trans rs1814175 0.791 rs10219223 chr11:49791468 A/T cg03929089 chr4:120376271 NA -0.9 -18.73 -0.71 2.27e-54 Height; LIHC cis rs6762 0.748 rs5030780 chr11:838110 C/T cg16425592 chr11:842748 TSPAN4;POLR2L -0.82 -10.46 -0.49 2.09e-22 Mean platelet volume; LIHC cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg18357526 chr6:26021779 HIST1H4A 0.62 8.69 0.43 1.58e-16 Blood metabolite levels; LIHC cis rs2066819 1.000 rs2371454 chr12:56647243 A/G cg26714650 chr12:56694279 CS 1.33 12.81 0.57 5.98e-31 Psoriasis vulgaris; LIHC trans rs62458065 0.513 rs7805536 chr7:32573570 T/C cg00845942 chr12:64062724 DPY19L2 -0.55 -6.05 -0.31 3.77e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg10360139 chr7:1886902 MAD1L1 -0.42 -6.42 -0.33 4.45e-10 Bipolar disorder and schizophrenia; LIHC cis rs7959452 0.718 rs10878963 chr12:69717166 T/G cg22834771 chr12:69754056 YEATS4 -0.35 -5.8 -0.3 1.49e-8 Blood protein levels; LIHC cis rs3018712 0.532 rs10791988 chr11:68416051 A/T cg16797656 chr11:68205561 LRP5 -0.45 -5.85 -0.3 1.12e-8 Total body bone mineral density; LIHC cis rs2980439 0.870 rs2945230 chr8:8109936 A/G cg06636001 chr8:8085503 FLJ10661 0.59 8.77 0.43 8.51e-17 Neuroticism; LIHC cis rs10504229 0.610 rs7840469 chr8:58146992 C/T cg20607798 chr8:58055168 NA 0.51 6.64 0.34 1.24e-10 Developmental language disorder (linguistic errors); LIHC trans rs116095464 0.558 rs59113266 chr5:279965 T/C cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs2070488 0.965 rs6805386 chr3:38557921 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.5 -0.62 1.81e-37 Electrocardiographic conduction measures; LIHC cis rs6430585 0.528 rs2278682 chr2:136743143 G/C cg07169764 chr2:136633963 MCM6 0.94 14.3 0.61 1.14e-36 Corneal structure; LIHC cis rs870825 0.929 rs72689256 chr4:185590174 C/T cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs5753037 0.702 rs81800 chr22:30200362 C/G cg01021169 chr22:30184971 ASCC2 0.34 6.66 0.34 1.08e-10 Type 1 diabetes; LIHC trans rs1728785 0.818 rs1069289 chr16:68585317 C/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.52 6.13 0.31 2.36e-9 Ulcerative colitis; LIHC cis rs11190604 1.000 rs7088827 chr10:102303865 C/G cg07080220 chr10:102295463 HIF1AN 0.52 7.3 0.37 2e-12 Palmitoleic acid (16:1n-7) levels; LIHC trans rs2727020 0.894 rs2866361 chr11:49372481 A/G cg18944383 chr4:111397179 ENPEP 0.28 6.52 0.33 2.56e-10 Coronary artery disease; LIHC cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg05564831 chr3:52568323 NT5DC2 0.36 5.8 0.3 1.54e-8 Bipolar disorder; LIHC cis rs4474465 0.790 rs6592785 chr11:78235095 C/T cg02023728 chr11:77925099 USP35 -0.33 -5.86 -0.3 1.07e-8 Alzheimer's disease (survival time); LIHC cis rs6952808 0.501 rs4721429 chr7:2171704 T/C cg21782813 chr7:2030301 MAD1L1 0.35 6.01 0.31 4.73e-9 Bipolar disorder and schizophrenia; LIHC cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs1580019 0.563 rs764483 chr7:32578150 A/T cg07520158 chr7:32535189 LSM5;AVL9 0.61 8.97 0.44 1.97e-17 Cognitive ability; LIHC cis rs6504950 0.800 rs9900816 chr17:53012057 G/A cg10237252 chr17:52977213 TOM1L1 -0.34 -5.99 -0.31 5.22e-9 Breast cancer; LIHC cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg24642844 chr7:1081250 C7orf50 -0.94 -9.36 -0.45 1.07e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs787274 1.000 rs10759584 chr9:115554736 T/G cg13803584 chr9:115635662 SNX30 -0.6 -6.68 -0.34 9.69e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs1559088 0.948 rs7257858 chr19:33591231 T/C cg17764715 chr19:33622953 WDR88 0.45 6.54 0.33 2.26e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1008375 0.933 rs4698637 chr4:17632843 A/T cg02297831 chr4:17616191 MED28 0.45 6.37 0.33 6.07e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6570726 0.935 rs372378 chr6:145816227 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.84 0.47 2.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs778371 0.915 rs938569 chr2:233759695 C/G cg08000102 chr2:233561755 GIGYF2 0.83 12.88 0.57 3.27e-31 Schizophrenia; LIHC cis rs7666738 0.546 rs10440329 chr4:98903735 C/T cg05340658 chr4:99064831 C4orf37 0.52 6.91 0.35 2.31e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs17384381 1.000 rs12132677 chr1:85879613 A/C cg16011679 chr1:85725395 C1orf52 0.8 8.49 0.42 6.31e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs3859192 0.561 rs34453912 chr17:38180352 T/A cg17467752 chr17:38218738 THRA -0.53 -9.16 -0.44 4.87e-18 White blood cell count; LIHC cis rs1003719 0.679 rs2835638 chr21:38534533 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.72 -10.95 -0.51 4.01e-24 Eye color traits; LIHC cis rs75908454 1.000 rs80174436 chr6:169971230 C/G cg19338460 chr6:170058176 WDR27 -0.82 -7.42 -0.37 9.52e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs2439831 0.717 rs7165471 chr15:43644788 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.99 0.51 2.94e-24 Lung cancer in ever smokers; LIHC cis rs12744310 1.000 rs55707527 chr1:41769113 G/T cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs9359856 0.564 rs11962292 chr6:90476788 C/T cg13799429 chr6:90582589 CASP8AP2 -0.66 -5.86 -0.3 1.11e-8 Bipolar disorder; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg02592271 chr2:27665507 KRTCAP3 -0.46 -6.41 -0.33 4.78e-10 Total body bone mineral density; LIHC cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.15e-9 Menopause (age at onset); LIHC cis rs10508774 1.000 rs3824591 chr10:32854400 T/C cg01819863 chr10:32635814 EPC1 0.65 6.1 0.31 2.87e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs561341 0.831 rs11658469 chr17:30206426 T/C cg13647721 chr17:30228624 UTP6 -0.74 -7.1 -0.36 7.45e-12 Hip circumference adjusted for BMI; LIHC cis rs6723226 0.708 rs2754513 chr2:32782763 G/A cg02381751 chr2:32503542 YIPF4 0.71 10.7 0.5 3.15e-23 Intelligence (multi-trait analysis); LIHC cis rs16958440 0.737 rs12327081 chr18:44744422 G/A cg17192377 chr18:44677553 HDHD2 0.73 5.74 0.3 2.12e-8 Sitting height ratio; LIHC trans rs3749237 0.964 rs10865959 chr3:49891002 G/C cg21665057 chr3:196295764 WDR53;FBXO45 0.61 9.36 0.45 1.12e-18 Resting heart rate; LIHC cis rs17433710 0.543 rs4657226 chr1:162653274 A/G cg01063088 chr1:162760584 HSD17B7 -0.42 -5.87 -0.3 1.03e-8 Dupuytren's disease; LIHC cis rs9916302 0.904 rs10852933 chr17:37698194 G/T cg00129232 chr17:37814104 STARD3 -0.42 -6.68 -0.34 9.86e-11 Glomerular filtration rate (creatinine); LIHC cis rs9649213 0.519 rs3735258 chr7:97866291 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.46 -7.7 -0.38 1.49e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs7412746 0.658 rs6677420 chr1:150946490 G/A cg18016565 chr1:150552671 MCL1 0.51 9.48 0.46 4.52e-19 Melanoma; LIHC cis rs2851682 1.000 rs2851682 chr11:61616012 A/G cg27386326 chr11:61587980 NA 0.59 8.57 0.42 3.65e-16 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs10791323 0.569 rs2156679 chr11:133742304 C/T cg06766960 chr11:133703094 NA -0.41 -6.21 -0.32 1.58e-9 Childhood ear infection; LIHC cis rs10791323 0.593 rs2282604 chr11:133714672 A/G cg06766960 chr11:133703094 NA -0.66 -11.24 -0.52 3.85e-25 Childhood ear infection; LIHC cis rs1865760 0.622 rs9968910 chr6:26072095 A/C cg16482183 chr6:26056742 HIST1H1C 0.47 6.43 0.33 4.19e-10 Height; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg05162900 chr17:28808449 GOSR1 -0.25 -6.47 -0.33 3.41e-10 Calcium levels; LIHC cis rs875971 0.964 rs9691480 chr7:65944306 A/C cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg08280861 chr8:58055591 NA 0.49 6.08 0.31 3.25e-9 Developmental language disorder (linguistic errors); LIHC cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg11890956 chr21:40555474 PSMG1 1.07 16.04 0.66 1.47e-43 Cognitive function; LIHC cis rs11971779 0.680 rs3924445 chr7:139044172 C/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs11671005 0.735 rs56292587 chr19:58919066 A/T cg25952890 chr19:58913133 NA 0.69 7.44 0.37 8.26e-13 Mean platelet volume; LIHC cis rs7221595 0.778 rs9916457 chr17:3929659 A/C cg09695851 chr17:3907499 NA 0.5 6.3 0.32 9.21e-10 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; LIHC cis rs4728302 0.869 rs13233715 chr7:133617471 C/T cg10665199 chr7:133106180 EXOC4 0.37 6.36 0.33 6.35e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg10755058 chr3:40428713 ENTPD3 0.34 5.8 0.3 1.48e-8 Renal cell carcinoma; LIHC cis rs7582180 0.652 rs4851311 chr2:100980398 C/T cg14675211 chr2:100938903 LONRF2 0.53 8.42 0.41 1.06e-15 Intelligence (multi-trait analysis); LIHC cis rs903552 0.935 rs12907726 chr15:102003626 C/G cg19295451 chr15:102010161 PCSK6 -0.44 -6.17 -0.32 1.97e-9 Diabetic kidney disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg15160873 chr2:128471243 WDR33 0.44 6.26 0.32 1.14e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs597539 0.652 rs673821 chr11:68678718 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.7 9.5 0.46 3.67e-19 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2304069 0.507 rs7728264 chr5:149394954 C/G cg12661370 chr5:149340060 SLC26A2 0.54 8.06 0.4 1.28e-14 HIV-1 control; LIHC cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs909341 0.808 rs2263805 chr20:62351150 T/C cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.74e-11 Atopic dermatitis; LIHC cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg22105103 chr4:187893119 NA 0.34 8.7 0.43 1.44e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs1348850 0.958 rs4893941 chr2:178269531 A/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.89 14.26 0.61 1.51e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs1816752 0.633 rs9578729 chr13:24999244 T/A cg02811702 chr13:24901961 NA 0.24 5.82 0.3 1.36e-8 Obesity-related traits; LIHC cis rs963731 0.649 rs1377861 chr2:39293858 T/C cg04010122 chr2:39346883 SOS1 -0.69 -6.18 -0.32 1.82e-9 Corticobasal degeneration; LIHC cis rs600806 0.713 rs12140694 chr1:109998386 C/T cg11161837 chr1:110010384 SYPL2 0.44 5.94 0.31 6.87e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs8017423 0.967 rs2277517 chr14:90722778 G/A cg04374321 chr14:90722782 PSMC1 0.77 15.34 0.64 9.18e-41 Mortality in heart failure; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19909895 chr3:128368930 RPN1 0.52 6.96 0.35 1.77e-11 Pancreatic cancer; LIHC cis rs10197940 0.578 rs2432957 chr2:152287897 A/C cg19508488 chr2:152266495 RIF1 0.49 6.97 0.35 1.67e-11 Lung cancer; LIHC cis rs9649465 0.935 rs3815458 chr7:123304323 A/T cg03229431 chr7:123269106 ASB15 -0.37 -8.03 -0.4 1.56e-14 Migraine; LIHC cis rs739401 0.572 rs12276060 chr11:3015572 A/T cg25174290 chr11:3078921 CARS 0.58 9.0 0.44 1.62e-17 Longevity; LIHC cis rs1005277 0.505 rs200936 chr10:38134935 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.6 -0.56 3.56e-30 Extrinsic epigenetic age acceleration; LIHC cis rs250677 0.687 rs42364 chr5:148438858 T/A cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs74417235 0.684 rs12655636 chr5:154057618 T/C cg19735590 chr5:154026979 NA 0.47 5.73 0.3 2.25e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs11673344 0.864 rs703537 chr19:37507729 G/A cg27390819 chr19:37464633 NA -0.5 -6.2 -0.32 1.66e-9 Obesity-related traits; LIHC cis rs36051895 0.554 rs11789744 chr9:5134213 G/A cg02405213 chr9:5042618 JAK2 -0.65 -10.66 -0.5 4.35e-23 Pediatric autoimmune diseases; LIHC trans rs9641123 0.579 rs2108164 chr7:93238340 T/A cg09745688 chr16:2908918 PRSS22 -0.37 -6.51 -0.33 2.71e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC trans rs11039798 0.920 rs11040015 chr11:48783130 G/T cg15704280 chr7:45808275 SEPT13 0.61 6.45 0.33 3.78e-10 Axial length; LIHC cis rs1008375 0.932 rs9283698 chr4:17662471 T/C cg02297831 chr4:17616191 MED28 0.42 5.87 0.3 1.04e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg03452623 chr4:187889614 NA -0.32 -8.31 -0.41 2.33e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs9896933 0.561 rs2264375 chr17:80692709 T/A cg20578329 chr17:80767326 TBCD -0.68 -6.9 -0.35 2.57e-11 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs4407350 0.756 rs131155 chr22:44891247 A/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.38 -0.33 5.63e-10 Intelligence (multi-trait analysis); LIHC cis rs7582180 0.764 rs4635546 chr2:100921125 G/A cg14675211 chr2:100938903 LONRF2 0.53 8.02 0.4 1.71e-14 Intelligence (multi-trait analysis); LIHC cis rs17401966 1.000 rs35766535 chr1:10284659 T/C cg19773385 chr1:10388646 KIF1B -0.46 -7.74 -0.39 1.16e-13 Hepatocellular carcinoma; LIHC cis rs7584330 1.000 rs7584330 chr2:238387228 A/G cg14458575 chr2:238380390 NA 0.37 6.02 0.31 4.57e-9 Prostate cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02364793 chr5:175964512 RNF44 0.36 6.12 0.31 2.58e-9 Pancreatic cancer; LIHC cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC trans rs9914544 0.966 rs9906795 chr17:18816740 G/A cg04702396 chr17:15466718 FAM18B2 0.45 7.02 0.35 1.23e-11 Educational attainment (years of education); LIHC cis rs1728785 1.000 rs1728781 chr16:68567794 A/T cg02972257 chr16:68554789 NA -0.51 -5.91 -0.3 8.23e-9 Ulcerative colitis; LIHC cis rs7552404 0.924 rs114752222 chr1:76180878 C/T cg10523679 chr1:76189770 ACADM 0.66 9.88 0.47 2.08e-20 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs17685 0.672 rs1639623 chr7:75707951 A/G cg04610667 chr7:75704037 NA -0.34 -6.09 -0.31 3.01e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs365132 0.934 rs6861925 chr5:176324729 C/G cg16309518 chr5:176445507 NA -0.55 -10.23 -0.48 1.33e-21 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg08888203 chr3:10149979 C3orf24 0.59 7.0 0.35 1.4e-11 Alzheimer's disease; LIHC cis rs56104184 0.725 rs4347731 chr19:49385154 A/G cg21252483 chr19:49399788 TULP2 -0.93 -9.08 -0.44 8.82e-18 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs1003719 0.788 rs2835576 chr21:38457393 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.21 0.55 1.02e-28 Eye color traits; LIHC cis rs11190604 0.666 rs7084768 chr10:102200497 T/C cg07080220 chr10:102295463 HIF1AN -0.47 -6.8 -0.35 4.57e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg27297192 chr10:134578999 INPP5A 0.53 8.15 0.4 6.85e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg18404041 chr3:52824283 ITIH1 -0.54 -8.9 -0.43 3.25e-17 Bipolar disorder; LIHC cis rs7833986 0.501 rs2719226 chr8:57044066 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.78 0.43 8.16e-17 Height; LIHC trans rs4843747 0.671 rs4072871 chr16:88106614 C/T cg09572067 chr16:29127029 RRN3P2 0.51 8.11 0.4 9.09e-15 Menopause (age at onset); LIHC cis rs3796352 0.881 rs35384050 chr3:53008769 G/T cg07884673 chr3:53033167 SFMBT1 0.9 6.6 0.34 1.58e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs60871478 0.645 rs111968669 chr7:856683 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.54 -6.03 -0.31 4.27e-9 Cerebrospinal P-tau181p levels; LIHC cis rs7412746 0.524 rs58304714 chr1:150831561 T/A cg17724175 chr1:150552817 MCL1 0.47 9.05 0.44 1.14e-17 Melanoma; LIHC cis rs738322 0.600 rs6001031 chr22:38556260 G/T cg25457927 chr22:38595422 NA 0.33 7.93 0.39 3.22e-14 Cutaneous nevi; LIHC cis rs2073300 0.793 rs36165478 chr20:23457261 C/T cg12062639 chr20:23401060 NAPB 0.77 9.63 0.46 1.36e-19 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs12142240 0.698 rs17357635 chr1:46808668 G/A cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs2153535 0.601 rs7775274 chr6:8530303 A/G cg23788917 chr6:8435910 SLC35B3 0.63 9.02 0.44 1.37e-17 Motion sickness; LIHC cis rs1144333 1.000 rs5745327 chr1:76270040 A/T cg03433033 chr1:76189801 ACADM -0.53 -8.14 -0.4 7.44e-15 Attention function in attention deficit hyperactive disorder; LIHC cis rs2637266 0.935 rs12414653 chr10:78394071 C/G cg18941641 chr10:78392320 NA 0.29 6.25 0.32 1.25e-9 Pulmonary function; LIHC cis rs12594515 1.000 rs35182335 chr15:45995184 C/G cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs5769765 0.955 rs9616367 chr22:50303515 A/C cg26441486 chr22:50317300 CRELD2 0.37 5.94 0.31 6.86e-9 Schizophrenia; LIHC cis rs208515 0.556 rs12206707 chr6:66697182 A/G cg07460842 chr6:66804631 NA 0.78 8.88 0.43 3.91e-17 Exhaled nitric oxide levels; LIHC cis rs34779708 0.702 rs35969476 chr10:35544318 G/A cg03585969 chr10:35415529 CREM 0.76 11.02 0.51 2.18e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9303401 0.659 rs35564417 chr17:56718286 G/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs2153535 0.580 rs9393016 chr6:8458573 T/A cg07606381 chr6:8435919 SLC35B3 0.8 12.04 0.55 4.4e-28 Motion sickness; LIHC cis rs634534 0.563 rs470192 chr11:65724291 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.94 0.44 2.42e-17 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs3780486 0.881 rs10738906 chr9:33135634 T/C cg20290983 chr6:43655470 MRPS18A 1.19 30.89 0.86 5.55e-101 IgG glycosylation; LIHC cis rs6545883 0.929 rs2264100 chr2:61670829 G/A cg15711740 chr2:61764176 XPO1 -0.43 -6.07 -0.31 3.33e-9 Tuberculosis; LIHC cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg03264133 chr6:25882463 NA -0.65 -8.11 -0.4 9.39e-15 Intelligence (multi-trait analysis); LIHC cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.51 -7.31 -0.37 1.94e-12 Lymphocyte counts; LIHC trans rs61931739 0.500 rs3922568 chr12:34560107 A/C cg26384229 chr12:38710491 ALG10B 0.64 8.15 0.4 6.78e-15 Morning vs. evening chronotype; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg06601766 chr17:61851465 DDX42;CCDC47 0.46 7.18 0.36 4.29e-12 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg07424592 chr7:64974309 NA -0.8 -9.28 -0.45 1.99e-18 Diabetic kidney disease; LIHC cis rs7927771 0.832 rs6485753 chr11:47410200 C/T cg20135002 chr11:47629003 NA 0.52 8.69 0.43 1.58e-16 Subjective well-being; LIHC cis rs9790314 1.000 rs336567 chr3:161073046 A/G cg04691961 chr3:161091175 C3orf57 -0.44 -6.97 -0.35 1.62e-11 Morning vs. evening chronotype; LIHC cis rs10857712 1.000 rs10857712 chr10:135225666 T/C cg19623624 chr10:135278901 LOC619207 -0.44 -6.88 -0.35 2.84e-11 Systemic lupus erythematosus; LIHC cis rs11583043 0.918 rs58029001 chr1:101393409 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.52 0.46 3.1400000000000002e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs12744310 1.000 rs12036554 chr1:41777989 T/G cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2834188 0.924 rs2850015 chr21:34697264 T/C cg04842828 chr21:34696676 IFNAR1 0.47 6.23 0.32 1.35e-9 Narcolepsy; LIHC cis rs4453791 0.932 rs13096744 chr3:38915335 T/G cg02254461 chr3:39195904 CSRNP1 0.66 5.89 0.3 9.44e-9 Social communication problems; LIHC cis rs892961 0.932 rs55661113 chr17:75408386 A/C cg05865280 chr17:75406074 SEPT9 0.61 11.08 0.51 1.43e-24 Airflow obstruction; LIHC cis rs1395 0.744 rs1975384 chr2:27542041 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.46 -6.04 -0.31 4e-9 Blood metabolite levels; LIHC cis rs11626933 1.000 rs61986782 chr14:90751344 C/T cg07150772 chr14:90864620 CALM1 -0.42 -5.87 -0.3 1.03e-8 Gut microbiota (bacterial taxa); LIHC cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.02 0.44 1.42e-17 Bipolar disorder; LIHC cis rs950776 0.518 rs12902493 chr15:78819275 C/G cg06917634 chr15:78832804 PSMA4 0.93 13.6 0.59 5.55e-34 Sudden cardiac arrest; LIHC cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg27286337 chr10:134555280 INPP5A 0.95 13.5 0.59 1.39e-33 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs922107 0.738 rs10922666 chr1:90036702 G/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.6 -0.38 2.8e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg10802521 chr3:52805072 NEK4 -0.44 -7.3 -0.37 2.02e-12 Bipolar disorder; LIHC cis rs1843834 0.539 rs6739735 chr2:225405253 A/G cg22455342 chr2:225449267 CUL3 -0.61 -8.94 -0.44 2.54e-17 IgE levels in asthmatics (D.p. specific); LIHC cis rs6066825 0.644 rs1040559 chr20:47314445 A/G cg18078177 chr20:47281410 PREX1 0.43 7.05 0.36 9.65e-12 Colorectal cancer; LIHC cis rs7715806 0.500 rs17563995 chr5:75007556 A/G cg19683494 chr5:74908142 NA 0.6 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3823572 0.504 rs2971968 chr7:133642599 C/A cg03336402 chr7:133662267 EXOC4 -0.47 -5.81 -0.3 1.4e-8 Intelligence (multi-trait analysis); LIHC cis rs1691799 0.867 rs1168311 chr12:66725912 A/C cg16791601 chr12:66731901 HELB 0.55 13.19 0.58 2.11e-32 White blood cell count (basophil); LIHC cis rs6714710 0.535 rs62158274 chr2:98621060 T/A cg26665480 chr2:98280029 ACTR1B 0.45 6.21 0.32 1.56e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg27170947 chr2:26402098 FAM59B -0.61 -7.76 -0.39 9.95e-14 Gut microbiome composition (summer); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg18368637 chr6:144179905 LTV1 0.39 6.08 0.31 3.2e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs11792861 0.781 rs17729408 chr9:111740860 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.62 -8.83 -0.43 5.64e-17 Menarche (age at onset); LIHC cis rs9560113 0.573 rs7988040 chr13:112226534 C/G cg10483660 chr13:112241077 NA 0.27 6.83 0.35 3.85e-11 Menarche (age at onset); LIHC cis rs17376456 0.569 rs7701114 chr5:93096028 T/C cg25358565 chr5:93447407 FAM172A 0.8 7.68 0.38 1.63e-13 Diabetic retinopathy; LIHC cis rs4919087 0.561 rs793522 chr10:99022614 T/G cg25902810 chr10:99078978 FRAT1 -0.57 -6.3 -0.32 9.33e-10 Monocyte count; LIHC cis rs12477438 0.715 rs6724476 chr2:99627316 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.59 -0.5 7.31e-23 Chronic sinus infection; LIHC cis rs4689592 0.619 rs3796908 chr4:7061378 G/A cg26116260 chr4:7069785 GRPEL1 0.96 17.29 0.68 1.4e-48 Monocyte percentage of white cells; LIHC cis rs6066825 0.606 rs2869668 chr20:47321393 T/C cg18078177 chr20:47281410 PREX1 0.4 6.58 0.34 1.8e-10 Colorectal cancer; LIHC cis rs12464559 0.522 rs10200512 chr2:152626147 T/C cg01189475 chr2:152685088 ARL5A 0.73 9.41 0.45 7.48e-19 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs892961 0.806 rs312910 chr17:75413961 A/C cg05865280 chr17:75406074 SEPT9 0.6 15.62 0.65 7.04e-42 Airflow obstruction; LIHC cis rs6582630 0.502 rs1115515 chr12:38279830 C/T cg26384229 chr12:38710491 ALG10B 0.82 10.21 0.48 1.51e-21 Drug-induced liver injury (flucloxacillin); LIHC cis rs7246657 0.943 rs10407084 chr19:37907792 T/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs6089584 0.888 rs6061979 chr20:60617141 C/G cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC cis rs797680 0.930 rs1474927 chr1:93570368 C/T cg15093775 chr1:93646470 TMED5;CCDC18 -0.32 -5.76 -0.3 1.9e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg26338869 chr17:61819248 STRADA 0.62 8.93 0.43 2.74e-17 Prudent dietary pattern; LIHC cis rs4808199 0.947 rs10404728 chr19:19595014 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.41 5.8 0.3 1.47e-8 Nonalcoholic fatty liver disease; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg02993280 chr1:107599747 PRMT6 -0.68 -10.87 -0.51 7.78e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2115630 0.936 rs6496318 chr15:85215229 C/T cg11189052 chr15:85197271 WDR73 -0.43 -6.35 -0.32 7.03e-10 P wave terminal force; LIHC cis rs7086627 0.506 rs10749575 chr10:82136921 C/T cg01528321 chr10:82214614 TSPAN14 0.41 6.07 0.31 3.43e-9 Post bronchodilator FEV1; LIHC cis rs1005277 0.540 rs11011351 chr10:38030525 A/G cg25427524 chr10:38739819 LOC399744 -0.63 -12.14 -0.55 1.97e-28 Extrinsic epigenetic age acceleration; LIHC cis rs367615 0.918 rs13173339 chr5:108871318 T/A cg17395555 chr5:108820864 NA 0.35 7.21 0.36 3.59e-12 Colorectal cancer (SNP x SNP interaction); LIHC cis rs798554 0.797 rs798493 chr7:2798731 A/G cg04166393 chr7:2884313 GNA12 0.46 6.38 0.33 5.59e-10 Height; LIHC cis rs2191566 1.000 rs10418363 chr19:44525463 A/G cg20607764 chr19:44506953 ZNF230 -0.45 -7.53 -0.38 4.6e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs477692 0.673 rs10764889 chr10:131341521 G/A cg05714579 chr10:131428358 MGMT 0.38 6.11 0.31 2.77e-9 Response to temozolomide; LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg07332563 chr6:291687 DUSP22 -0.53 -7.39 -0.37 1.12e-12 Menopause (age at onset); LIHC cis rs7582180 0.764 rs920269 chr2:100918363 G/A cg14675211 chr2:100938903 LONRF2 0.52 7.91 0.39 3.53e-14 Intelligence (multi-trait analysis); LIHC trans rs10411161 0.702 rs11879436 chr19:52397815 T/A cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg20607798 chr8:58055168 NA 0.64 8.21 0.41 4.61e-15 Developmental language disorder (linguistic errors); LIHC cis rs941408 0.515 rs759067 chr19:2775668 C/T cg02580895 chr19:2754563 NA -0.46 -6.83 -0.35 3.96e-11 Total cholesterol levels; LIHC cis rs10791097 0.694 rs2155752 chr11:130755998 C/T cg12179176 chr11:130786555 SNX19 0.85 13.94 0.6 2.63e-35 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7903847 0.642 rs6584127 chr10:99142948 A/C cg20016023 chr10:99160130 RRP12 -0.42 -6.57 -0.33 1.9e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg11062466 chr8:58055876 NA 0.51 7.47 0.37 6.66e-13 Developmental language disorder (linguistic errors); LIHC cis rs13118159 0.934 rs4974553 chr4:1356911 G/A cg13395646 chr4:1353034 KIAA1530 -0.7 -9.6 -0.46 1.73e-19 Longevity; LIHC cis rs3736485 0.966 rs11633713 chr15:51908052 C/T cg08986416 chr15:51914746 DMXL2 -0.47 -6.97 -0.35 1.64e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs763014 1.000 rs2269558 chr16:682250 C/T cg27189623 chr16:705930 WDR90 0.42 6.96 0.35 1.74e-11 Height; LIHC cis rs6754311 0.731 rs309164 chr2:136691825 T/C cg15123519 chr2:136567270 LCT -0.36 -7.25 -0.37 2.71e-12 Mosquito bite size; LIHC cis rs208520 1.000 rs208537 chr6:66963544 A/G cg07460842 chr6:66804631 NA -0.65 -7.0 -0.35 1.36e-11 Exhaled nitric oxide output; LIHC cis rs17376456 0.809 rs12152763 chr5:93405509 T/A cg25358565 chr5:93447407 FAM172A 1.12 10.25 0.48 1.1e-21 Diabetic retinopathy; LIHC cis rs12497850 0.897 rs9850134 chr3:48957147 A/G cg06212747 chr3:49208901 KLHDC8B 0.56 7.22 0.36 3.44e-12 Parkinson's disease; LIHC cis rs483180 0.512 rs597308 chr1:120214953 G/A cg19096424 chr1:120255104 PHGDH 0.63 7.9 0.39 3.98e-14 Macular telangiectasia type 2; LIHC cis rs10193935 0.901 rs59984817 chr2:42566909 C/G cg27598129 chr2:42591480 NA -0.71 -11.24 -0.52 3.68e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs55665837 0.701 rs11023278 chr11:14641184 G/T cg25251204 chr11:14927456 NA 0.43 6.03 0.31 4.22e-9 Vitamin D levels; LIHC cis rs6466055 0.777 rs3801281 chr7:104889573 T/C cg04380332 chr7:105027541 SRPK2 0.36 6.71 0.34 8.15e-11 Schizophrenia; LIHC cis rs2839627 0.561 rs4148970 chr21:44313293 A/G cg03543861 chr21:44258195 NA 0.53 8.7 0.43 1.45e-16 Information processing speed; LIHC cis rs12586317 0.620 rs8021414 chr14:35581480 T/A cg16230307 chr14:35515116 FAM177A1 0.79 13.24 0.58 1.31e-32 Psoriasis; LIHC cis rs2749592 0.513 rs1208708 chr10:38085576 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.4 -5.99 -0.31 5.36e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10744422 0.800 rs839363 chr12:123276924 C/T cg18912006 chr12:123335444 HIP1R -0.55 -6.32 -0.32 8.05e-10 Schizophrenia; LIHC cis rs2573652 1.000 rs2581362 chr15:100513524 T/C cg09918751 chr15:100517450 ADAMTS17 -0.81 -14.35 -0.61 7.14e-37 Height; LIHC cis rs7432375 0.933 rs6791142 chr3:136377377 C/T cg21827317 chr3:136751795 NA 0.43 5.91 0.3 8.26e-9 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.36 0.45 1.12e-18 Platelet count; LIHC cis rs1707322 0.752 rs28890893 chr1:46186576 T/G cg03146154 chr1:46216737 IPP 0.58 9.48 0.46 4.38e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg06481639 chr22:41940642 POLR3H 0.7 7.28 0.37 2.38e-12 Vitiligo; LIHC cis rs2991971 1.000 rs9147 chr1:46016687 T/C cg24296786 chr1:45957014 TESK2 0.5 7.16 0.36 4.82e-12 High light scatter reticulocyte count; LIHC cis rs909341 0.716 rs71325464 chr20:62363453 A/G cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.74e-11 Atopic dermatitis; LIHC cis rs62103177 0.564 rs2115996 chr18:77701007 C/G cg20368463 chr18:77673604 PQLC1 0.52 6.41 0.33 4.69e-10 Opioid sensitivity; LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg11905131 chr22:24372483 LOC391322 -0.64 -8.82 -0.43 5.93e-17 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7216064 0.953 rs4790905 chr17:65863350 C/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs9733 0.650 rs6698495 chr1:150564476 T/C cg18016565 chr1:150552671 MCL1 -0.54 -11.1 -0.51 1.2e-24 Tonsillectomy; LIHC cis rs2979489 0.891 rs2915591 chr8:30395948 C/G cg26383811 chr8:30366931 RBPMS -0.72 -11.81 -0.54 3.28e-27 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs7772486 0.875 rs9403764 chr6:146360582 G/A cg23711669 chr6:146136114 FBXO30 0.66 11.84 0.54 2.47e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs6938574 0.672 rs6569520 chr6:128365034 C/G cg13759676 chr6:128799557 PTPRK -0.44 -5.72 -0.3 2.35e-8 Menarche (age at onset); LIHC cis rs7000551 0.751 rs2449329 chr8:22374794 G/T cg12081754 chr8:22256438 SLC39A14 0.42 6.6 0.34 1.6e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs4665809 0.938 rs4665822 chr2:26312555 C/G cg26119090 chr2:26468346 HADHA;HADHB -0.72 -9.02 -0.44 1.34e-17 Gut microbiome composition (summer); LIHC cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg00750074 chr16:89608354 SPG7 -0.46 -7.55 -0.38 4.06e-13 Multiple myeloma (IgH translocation); LIHC cis rs6964587 0.773 rs12536421 chr7:92008220 A/G cg17063962 chr7:91808500 NA 0.97 16.32 0.66 1.07e-44 Breast cancer; LIHC cis rs4819052 0.851 rs7275468 chr21:46656499 C/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.48 6.68 0.34 9.78e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg25364880 chr3:44379878 C3orf23 0.54 7.39 0.37 1.16e-12 Depressive symptoms; LIHC cis rs1555322 0.530 rs2425049 chr20:33874720 C/T cg03689076 chr20:33865952 NA 0.54 6.32 0.32 8.02e-10 Attention deficit hyperactivity disorder; LIHC cis rs6570726 0.935 rs419847 chr6:145827278 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.9 0.47 1.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs9399135 1.000 rs4475342 chr6:135283348 T/C cg24558204 chr6:135376177 HBS1L 0.39 6.35 0.32 7.05e-10 Red blood cell count; LIHC cis rs11605275 1.000 rs74809393 chr11:20031520 C/A cg14835545 chr11:20032148 NAV2 -0.8 -7.38 -0.37 1.18e-12 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs72781680 0.950 rs72796343 chr2:24147631 G/A cg08917208 chr2:24149416 ATAD2B 0.94 8.07 0.4 1.17e-14 Lymphocyte counts; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01162549 chr5:141367464 RNF14 0.47 6.98 0.35 1.59e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs6964587 1.000 rs6946356 chr7:91727385 G/A cg17063962 chr7:91808500 NA 1.01 19.17 0.72 3.67e-56 Breast cancer; LIHC cis rs2228479 0.681 rs10153055 chr16:89965842 C/T cg19635926 chr16:89946313 TCF25 0.51 6.7 0.34 8.85e-11 Skin colour saturation; LIHC cis rs4253772 0.591 rs6008361 chr22:46652372 A/G cg09491104 chr22:46646882 C22orf40 0.61 7.07 0.36 8.72e-12 LDL cholesterol;Cholesterol, total; LIHC cis rs17376456 1.000 rs59472588 chr5:93511981 A/G cg25358565 chr5:93447407 FAM172A 1.08 9.91 0.47 1.64e-20 Diabetic retinopathy; LIHC cis rs9303401 0.614 rs8081058 chr17:57160513 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.88 11.91 0.54 1.31e-27 Cognitive test performance; LIHC cis rs12477438 0.834 rs6757019 chr2:99676936 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.78 -11.67 -0.53 1.03e-26 Chronic sinus infection; LIHC cis rs7223966 1.000 rs2854223 chr17:61939014 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 7.29 0.37 2.18e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg05368731 chr17:41323189 NBR1 0.73 12.44 0.56 1.51e-29 Menopause (age at onset); LIHC cis rs600231 0.665 rs12790095 chr11:65326086 T/G cg17120908 chr11:65337727 SSSCA1 -0.45 -6.38 -0.33 5.62e-10 Bone mineral density; LIHC cis rs9296092 0.517 rs7743064 chr6:33470529 C/T cg13560919 chr6:33536144 NA -0.38 -6.06 -0.31 3.58e-9 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7954584 0.520 rs1169095 chr12:122465738 G/A cg22618164 chr12:122356400 WDR66 -0.46 -7.59 -0.38 3.03e-13 Mean corpuscular volume; LIHC cis rs561341 0.700 rs8079471 chr17:30218317 A/G cg13647721 chr17:30228624 UTP6 0.69 7.88 0.39 4.37e-14 Hip circumference adjusted for BMI; LIHC trans rs9951602 0.512 rs9304070 chr18:76654890 A/C cg02800362 chr5:177631904 HNRNPAB 0.65 10.45 0.49 2.22e-22 Obesity-related traits; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg25010118 chr18:65184398 DSEL 0.43 6.47 0.33 3.42e-10 Alopecia areata; LIHC cis rs208520 1.000 rs12195505 chr6:66986279 T/A cg07460842 chr6:66804631 NA 0.67 7.29 0.37 2.24e-12 Exhaled nitric oxide output; LIHC cis rs11822910 0.654 rs2439450 chr11:57213061 C/G cg00522883 chr11:57194120 SLC43A3 0.52 6.75 0.34 6.2e-11 Platelet distribution width; LIHC cis rs11122272 0.735 rs2808611 chr1:231548480 A/G cg06096015 chr1:231504339 EGLN1 -0.5 -9.39 -0.45 8.51e-19 Hemoglobin concentration; LIHC cis rs4555082 1.000 rs4277291 chr14:105759009 A/G cg06808227 chr14:105710500 BRF1 -0.49 -6.49 -0.33 3.08e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs7100689 0.784 rs2153455 chr10:82139732 T/C cg01528321 chr10:82214614 TSPAN14 0.9 13.15 0.58 2.99e-32 Post bronchodilator FEV1; LIHC cis rs10504073 0.584 rs10957356 chr8:49980634 G/A cg00325661 chr8:49890786 NA 0.33 7.6 0.38 2.9e-13 Blood metabolite ratios; LIHC trans rs6866721 0.791 rs10071722 chr5:116214932 T/G cg07571379 chr11:134631427 NA -0.29 -6.09 -0.31 3.08e-9 Body mass index; LIHC cis rs2120019 0.938 rs59094290 chr15:75308561 G/T cg17294928 chr15:75287854 SCAMP5 -0.49 -7.26 -0.37 2.63e-12 Blood trace element (Zn levels); LIHC cis rs892961 0.932 rs67415822 chr17:75412678 A/G cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs7772486 0.846 rs1331636 chr6:146338826 T/C cg05347473 chr6:146136440 FBXO30 0.37 5.99 0.31 5.45e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC trans rs2243480 1.000 rs73142166 chr7:65375832 A/G cg10756647 chr7:56101905 PSPH 1.1 13.25 0.58 1.24e-32 Diabetic kidney disease; LIHC trans rs35110281 0.805 rs3788062 chr21:44991159 C/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.44 6.09 0.31 3.11e-9 Mean corpuscular volume; LIHC cis rs892961 0.932 rs8066646 chr17:75414192 C/T cg05865280 chr17:75406074 SEPT9 0.65 13.41 0.59 3.07e-33 Airflow obstruction; LIHC cis rs1552244 0.882 rs7636817 chr3:10014876 G/T cg08888203 chr3:10149979 C3orf24 0.47 6.07 0.31 3.35e-9 Alzheimer's disease; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21806233 chr11:111956119 TIMM8B;SDHD 0.44 6.11 0.31 2.64e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 14.27 0.61 1.39e-36 Prudent dietary pattern; LIHC cis rs4969178 0.600 rs4969183 chr17:76393372 A/G cg20026190 chr17:76395443 PGS1 0.39 5.84 0.3 1.2e-8 HDL cholesterol levels; LIHC cis rs8078723 0.668 rs4239225 chr17:38127112 G/A cg17467752 chr17:38218738 THRA 0.61 10.61 0.5 6.35e-23 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs116248771 0.739 rs4679833 chr3:158339835 G/A cg16708174 chr3:158430962 RARRES1 0.48 6.36 0.33 6.52e-10 diarrhoeal disease at age 2; LIHC cis rs4919087 1.000 rs10786329 chr10:99074621 G/A cg25902810 chr10:99078978 FRAT1 0.7 10.78 0.5 1.65e-23 Monocyte count; LIHC cis rs1570989 0.841 rs956598 chr6:12027635 A/G cg17804551 chr6:12015979 HIVEP1 0.4 5.99 0.31 5.27e-9 Alcohol and nicotine co-dependence; LIHC cis rs888194 0.725 rs2241210 chr12:109950144 A/G cg05360138 chr12:110035743 NA 0.4 5.74 0.3 2.07e-8 Neuroticism; LIHC cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg08888203 chr3:10149979 C3orf24 0.61 6.87 0.35 3.14e-11 Alzheimer's disease; LIHC cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg18404041 chr3:52824283 ITIH1 -0.58 -9.65 -0.46 1.16e-19 Electroencephalogram traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07288394 chr19:30205772 C19orf12 0.45 6.17 0.32 1.91e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10508774 1.000 rs11008940 chr10:32731979 A/T cg01819863 chr10:32635814 EPC1 -0.65 -6.06 -0.31 3.49e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg16145915 chr7:1198662 ZFAND2A -0.45 -12.47 -0.56 1.17e-29 Longevity;Endometriosis; LIHC cis rs922107 0.738 rs7516314 chr1:90050831 A/G cg15422784 chr1:90023713 LRRC8B -0.49 -7.76 -0.39 9.62e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs10838687 0.736 rs4647741 chr11:47254010 T/C cg25783544 chr11:47291846 MADD 0.47 5.87 0.3 1.05e-8 Proinsulin levels; LIHC trans rs35110281 0.782 rs7282933 chr21:45046988 A/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.25 0.32 1.21e-9 Mean corpuscular volume; LIHC cis rs10949834 0.793 rs810532 chr7:73505188 A/G cg07137043 chr7:73588983 EIF4H -0.56 -6.25 -0.32 1.21e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs7208859 0.673 rs2470251 chr17:29095061 T/C cg14067834 chr17:29058358 SUZ12P 0.65 6.65 0.34 1.17e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17685 0.712 rs10235086 chr7:75833138 G/T cg01364799 chr7:75623366 TMEM120A -0.51 -7.59 -0.38 3.11e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs875971 0.862 rs17747530 chr7:65994729 G/C cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.38e-11 Aortic root size; LIHC cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg14004847 chr7:1930337 MAD1L1 -0.41 -5.81 -0.3 1.45e-8 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg02290350 chr8:58132656 NA 0.47 9.29 0.45 1.8e-18 Developmental language disorder (linguistic errors); LIHC cis rs7487075 0.780 rs12307969 chr12:46759057 G/C cg22049899 chr12:47219821 SLC38A4 0.36 6.28 0.32 1.01e-9 Itch intensity from mosquito bite; LIHC cis rs3820068 0.705 rs59502343 chr1:15872617 T/C cg17385448 chr1:15911702 AGMAT 0.4 6.81 0.35 4.41e-11 Systolic blood pressure; LIHC cis rs1018836 0.818 rs715057 chr8:91624340 T/C cg16814680 chr8:91681699 NA -0.61 -9.84 -0.47 2.84e-20 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs4268898 0.552 rs11125455 chr2:24374557 C/G cg06627628 chr2:24431161 ITSN2 0.49 7.1 0.36 7.31e-12 Asthma; LIHC cis rs6088580 0.505 rs6142219 chr20:33256345 G/A cg08999081 chr20:33150536 PIGU -0.43 -7.17 -0.36 4.73e-12 Glomerular filtration rate (creatinine); LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg16034541 chr3:195490309 MUC4 0.61 9.61 0.46 1.59e-19 Lung disease severity in cystic fibrosis; LIHC cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg24250549 chr1:154909240 PMVK 0.67 10.57 0.5 8.43e-23 Prostate cancer; LIHC cis rs7551222 0.752 rs1380576 chr1:204488278 G/C cg20240347 chr1:204465584 NA -0.36 -7.57 -0.38 3.39e-13 Schizophrenia; LIHC cis rs11583043 1.000 rs6660290 chr1:101483512 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.53 -6.42 -0.33 4.68e-10 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs875971 0.619 rs10278371 chr7:66051540 C/A cg26939375 chr7:64535504 NA -0.46 -7.32 -0.37 1.81e-12 Aortic root size; LIHC cis rs807029 0.533 rs722435 chr10:102745062 G/T cg27255678 chr10:102756921 LZTS2 0.52 7.31 0.37 1.85e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2836974 0.627 rs8127986 chr21:40687211 A/T cg06238570 chr21:40685208 BRWD1 -0.54 -9.08 -0.44 8.82e-18 Cognitive function; LIHC cis rs6088590 0.523 rs6088536 chr20:33189106 T/C cg08999081 chr20:33150536 PIGU 0.69 13.68 0.59 2.84e-34 Coronary artery disease; LIHC cis rs910316 0.967 rs119076 chr14:75572419 G/T cg11812906 chr14:75593930 NEK9 -0.76 -15.24 -0.64 2.18e-40 Height; LIHC cis rs10420951 0.617 rs2303694 chr19:18562438 C/T cg10790698 chr19:18539756 SSBP4 -0.42 -6.03 -0.31 4.15e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6430585 0.591 rs77096272 chr2:136663605 C/A cg25344623 chr2:136566232 LCT -0.38 -6.05 -0.31 3.71e-9 Corneal structure; LIHC cis rs1395 0.744 rs9653564 chr2:27472618 G/A cg23587288 chr2:27483067 SLC30A3 -0.35 -6.59 -0.34 1.67e-10 Blood metabolite levels; LIHC cis rs7572733 0.515 rs1356542 chr2:198835702 G/T cg03934865 chr2:198174659 NA 0.46 6.76 0.34 5.8e-11 Dermatomyositis; LIHC cis rs9660992 0.590 rs1779411 chr1:205238530 C/T cg21545522 chr1:205238299 TMCC2 0.42 8.0 0.4 1.96e-14 Mean corpuscular volume;Mean platelet volume; LIHC cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg27170947 chr2:26402098 FAM59B 0.66 8.46 0.42 8.14e-16 Gut microbiome composition (summer); LIHC cis rs1385374 0.858 rs3741615 chr12:129298848 G/A cg09035930 chr12:129282057 SLC15A4 -0.5 -5.95 -0.31 6.49e-9 Systemic lupus erythematosus; LIHC cis rs10508774 0.925 rs72795540 chr10:32843182 C/T cg01819863 chr10:32635814 EPC1 0.66 6.14 0.32 2.25e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs713477 0.631 rs7145182 chr14:55905231 C/G cg13175173 chr14:55914753 NA -0.3 -6.68 -0.34 9.83e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs2404602 0.692 rs12910382 chr15:77053442 A/C cg03037974 chr15:76606532 NA 0.75 14.64 0.62 4.9e-38 Blood metabolite levels; LIHC cis rs600806 0.815 rs10858088 chr1:109923586 C/T cg08911820 chr1:110026001 ATXN7L2 -0.61 -7.51 -0.38 5.14e-13 Intelligence (multi-trait analysis); LIHC cis rs6582630 0.555 rs7978749 chr12:38527141 G/T cg13010199 chr12:38710504 ALG10B 0.43 5.87 0.3 1.03e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.55 7.18 0.36 4.51e-12 Osteoporosis; LIHC trans rs5756813 0.661 rs7286550 chr22:38196760 G/A cg19894588 chr14:64061835 NA -0.68 -10.07 -0.48 4.52e-21 Optic cup area;Vertical cup-disc ratio; LIHC cis rs17106184 1.000 rs11205773 chr1:51284905 C/T cg07174182 chr1:51127561 FAF1 0.75 8.4 0.41 1.24e-15 Type 2 diabetes; LIHC cis rs11673344 0.730 rs475026 chr19:37459017 T/C cg27390819 chr19:37464633 NA -0.53 -6.29 -0.32 9.74e-10 Obesity-related traits; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg04895581 chr8:94753488 RBM12B -0.41 -6.2 -0.32 1.59e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.33e-30 Menopause (age at onset); LIHC cis rs16958440 0.867 rs78547658 chr18:44669852 C/T cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC cis rs6594499 0.872 rs10051830 chr5:110452845 G/A cg04022379 chr5:110408740 TSLP 0.49 8.16 0.4 6.26e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs6500602 0.702 rs2304634 chr16:4500544 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.38 5.73 0.3 2.18e-8 Schizophrenia; LIHC cis rs1580019 0.547 rs56981934 chr7:32535202 C/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.1 0.31 2.85e-9 Cognitive ability; LIHC cis rs11048434 0.736 rs1805761 chr12:9099533 T/C cg04155231 chr12:9217510 LOC144571 0.3 5.87 0.3 1.05e-8 Sjögren's syndrome; LIHC cis rs17685 0.712 rs28456330 chr7:75810542 A/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.8 -0.39 7.52e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2075371 0.796 rs1646644 chr7:134011817 A/T cg11752832 chr7:134001865 SLC35B4 0.4 6.21 0.32 1.52e-9 Mean platelet volume; LIHC cis rs4076764 0.957 rs4443867 chr1:163434917 T/C cg24596788 chr1:163392923 NA -0.23 -7.28 -0.37 2.24e-12 Motion sickness; LIHC cis rs12594515 0.904 rs8032875 chr15:45998010 A/C cg19682013 chr15:45996608 NA 0.39 6.63 0.34 1.29e-10 Waist circumference;Weight; LIHC cis rs4665809 1.000 rs6739061 chr2:26256147 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.67 -8.23 -0.41 4.1e-15 Gut microbiome composition (summer); LIHC cis rs11588062 0.601 rs11579255 chr1:46806959 C/T cg06787764 chr1:46668870 C1orf190;POMGNT1 0.48 7.47 0.37 6.61e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs2727020 0.576 rs10839305 chr11:49598733 T/C cg18944383 chr4:111397179 ENPEP 0.25 6.28 0.32 1.02e-9 Coronary artery disease; LIHC cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg22907277 chr7:1156413 C7orf50 0.51 7.75 0.39 1.07e-13 Longevity;Endometriosis; LIHC cis rs6951245 0.706 rs28685743 chr7:1197736 C/T cg24642844 chr7:1081250 C7orf50 -0.6 -5.93 -0.31 7.38e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg12310025 chr6:25882481 NA 0.88 12.41 0.56 1.83e-29 Blood metabolite levels; LIHC cis rs2439831 1.000 rs690002 chr15:43729349 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.67 0.59 3.13e-34 Lung cancer in ever smokers; LIHC cis rs10744422 1.000 rs1587856 chr12:123342229 A/G cg22842854 chr12:123319900 HIP1R -0.74 -9.73 -0.47 6.52e-20 Schizophrenia; LIHC cis rs7044106 0.791 rs4836829 chr9:123482747 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 8.21 0.41 4.46e-15 Hip circumference adjusted for BMI; LIHC cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.69 0.38 1.54e-13 Bipolar disorder; LIHC trans rs2243480 1.000 rs781156 chr7:65479141 C/A cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 0.91 10.0 0.48 7.94e-21 Platelet count; LIHC cis rs6582630 0.555 rs1829583 chr12:38423161 T/C cg26384229 chr12:38710491 ALG10B -0.59 -8.59 -0.42 3.2e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs763121 0.853 rs5757232 chr22:39071677 C/T cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs2073300 0.609 rs3736755 chr20:23377642 C/T cg16736954 chr20:23401023 NAPB 0.7 8.34 0.41 1.89e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6466055 0.720 rs1204058 chr7:104958129 T/G cg04380332 chr7:105027541 SRPK2 0.37 6.88 0.35 2.84e-11 Schizophrenia; LIHC cis rs9457247 1.000 rs364283 chr6:167383750 C/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.73 0.47 6.7e-20 Crohn's disease; LIHC cis rs634534 0.562 rs1151505 chr11:65734539 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.44 6.94 0.35 1.94e-11 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs8081395 0.627 rs12952730 chr17:57978836 G/A cg02344993 chr17:57696989 CLTC 0.45 7.56 0.38 3.86e-13 White blood cell count; LIHC cis rs644799 0.965 rs502521 chr11:95533557 T/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.82 0.3 1.38e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs796364 0.806 rs74266490 chr2:201005995 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs11166927 0.594 rs7828992 chr8:140826670 A/G cg16909799 chr8:140841666 TRAPPC9 -0.46 -7.27 -0.37 2.49e-12 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs12130219 0.500 rs4845743 chr1:152184149 A/G cg26320663 chr1:152161521 NA 0.41 6.14 0.32 2.29e-9 Inflammatory skin disease; LIHC cis rs4853012 0.838 rs72911122 chr2:74344119 C/G cg01017244 chr2:74357527 NA 0.63 11.29 0.52 2.45e-25 Gestational age at birth (maternal effect); LIHC cis rs11190604 1.000 rs11816840 chr10:102309220 G/C cg07080220 chr10:102295463 HIF1AN 0.51 7.1 0.36 7.39e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2153535 0.580 rs1577471 chr6:8485905 T/A cg07606381 chr6:8435919 SLC35B3 0.8 12.01 0.54 5.63e-28 Motion sickness; LIHC cis rs8180040 0.932 rs12489046 chr3:47527683 T/G cg27129171 chr3:47204927 SETD2 0.58 9.91 0.47 1.65e-20 Colorectal cancer; LIHC cis rs11252926 0.510 rs4881371 chr10:554514 G/A cg09445902 chr10:555545 DIP2C -0.4 -6.53 -0.33 2.39e-10 Psychosis in Alzheimer's disease; LIHC cis rs9868809 0.505 rs11719291 chr3:48735706 A/G cg07636037 chr3:49044803 WDR6 -0.7 -7.35 -0.37 1.46e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg11987759 chr7:65425863 GUSB 0.39 6.22 0.32 1.41e-9 Aortic root size; LIHC cis rs7520050 0.966 rs785503 chr1:46595868 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.8 0.3 1.5e-8 Red blood cell count;Reticulocyte count; LIHC cis rs713477 1.000 rs7148481 chr14:55909267 G/A cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.32e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg07414643 chr4:187882934 NA 0.24 6.03 0.31 4.22e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg10802521 chr3:52805072 NEK4 -0.44 -7.45 -0.37 7.75e-13 Bipolar disorder; LIHC cis rs9611565 0.649 rs139553 chr22:42187199 A/G cg03806693 chr22:41940476 POLR3H 0.74 8.01 0.4 1.83e-14 Vitiligo; LIHC cis rs870825 0.929 rs10027213 chr4:185579871 C/G cg04058563 chr4:185651563 MLF1IP 0.7 5.91 0.3 8.22e-9 Blood protein levels; LIHC cis rs9581857 0.556 rs9579085 chr13:28041039 G/A cg22138327 chr13:27999177 GTF3A 0.46 6.79 0.34 5.08e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs12497850 0.931 rs6414613 chr3:49035885 C/T cg06212747 chr3:49208901 KLHDC8B 0.57 7.25 0.37 2.79e-12 Parkinson's disease; LIHC cis rs801193 1.000 rs2659906 chr7:66165310 T/C cg11764359 chr7:65958608 NA 0.71 10.55 0.5 1.02e-22 Aortic root size; LIHC cis rs950169 0.922 rs4842946 chr15:84942331 G/A cg03959625 chr15:84868606 LOC388152 0.47 6.68 0.34 9.94e-11 Schizophrenia; LIHC cis rs34540877 1.000 rs58229578 chr19:33138336 C/T cg22980127 chr19:33182716 NUDT19 1.0 6.63 0.34 1.3e-10 Red cell distribution width; LIHC cis rs7843479 1.000 rs13248727 chr8:21842063 T/C cg17168535 chr8:21777572 XPO7 0.41 6.7 0.34 8.62e-11 Mean corpuscular volume; LIHC cis rs7264396 0.790 rs3787164 chr20:34228866 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -9.55 -0.46 2.51e-19 Total cholesterol levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15344021 chr17:2240169 TSR1;SGSM2 0.44 6.17 0.32 1.97e-9 Pancreatic cancer; LIHC cis rs4903214 0.895 rs1860716 chr14:74713273 T/A cg11132536 chr14:74711944 VSX2 -0.24 -5.95 -0.31 6.46e-9 Inflammatory bowel disease; LIHC cis rs7959452 0.535 rs10784771 chr12:69621264 A/G cg14784868 chr12:69753453 YEATS4 0.81 14.95 0.63 3.01e-39 Blood protein levels; LIHC cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg07308232 chr7:1071921 C7orf50 -0.47 -7.57 -0.38 3.5e-13 Longevity;Endometriosis; LIHC cis rs7659604 0.517 rs56311153 chr4:122729685 T/C cg20573242 chr4:122745356 CCNA2 0.53 7.69 0.38 1.58e-13 Type 2 diabetes; LIHC cis rs700651 0.789 rs116165148 chr2:198888347 T/G cg03934865 chr2:198174659 NA 0.43 6.2 0.32 1.62e-9 Intracranial aneurysm; LIHC cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg07424592 chr7:64974309 NA 0.82 9.43 0.45 6.33e-19 Diabetic kidney disease; LIHC cis rs875971 0.545 rs4441996 chr7:65588220 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.37 -7.46 -0.37 7.13e-13 Aortic root size; LIHC trans rs743793 0.875 rs137380 chr22:33578233 T/A cg20274824 chr1:36638199 MAP7D1 0.46 6.42 0.33 4.66e-10 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs875971 1.000 rs11971949 chr7:65626014 A/G cg18876405 chr7:65276391 NA -0.38 -6.73 -0.34 7.21e-11 Aortic root size; LIHC trans rs1814175 0.645 rs28478790 chr11:50054322 C/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs1664789 1.000 rs1664784 chr5:53281366 A/T ch.5.1024479R chr5:53302184 ARL15 0.53 8.69 0.43 1.58e-16 Waist circumference adjusted for body mass index; LIHC cis rs7208859 0.623 rs9911173 chr17:29154750 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.76 0.34 5.89e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs68170813 0.559 rs6951639 chr7:106817639 A/G cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs5769707 0.706 rs763128 chr22:50018045 G/A cg07959070 chr22:50026188 C22orf34 -0.35 -8.66 -0.42 1.92e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6545883 0.894 rs2694639 chr2:61595291 G/A cg14146966 chr2:61757674 XPO1 -0.43 -7.24 -0.36 2.94e-12 Tuberculosis; LIHC cis rs2832191 0.597 rs8127842 chr21:30516461 G/A cg08807101 chr21:30365312 RNF160 -0.44 -6.33 -0.32 7.8e-10 Dental caries; LIHC cis rs7020830 0.898 rs13289199 chr9:37278064 A/T cg14294708 chr9:37120828 ZCCHC7 1.02 20.36 0.74 6.46e-61 Schizophrenia; LIHC cis rs1865760 0.625 rs9393681 chr6:26008260 A/G cg18357526 chr6:26021779 HIST1H4A 0.47 6.97 0.35 1.6e-11 Height; LIHC cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg08132940 chr7:1081526 C7orf50 -0.77 -6.47 -0.33 3.47e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9929218 0.953 rs34909703 chr16:68740097 T/C cg01231543 chr16:68741748 NA 0.39 5.98 0.31 5.67e-9 Colorectal cancer; LIHC trans rs6866721 0.791 rs10054140 chr5:116215213 C/T cg07571379 chr11:134631427 NA -0.29 -6.09 -0.31 3.08e-9 Body mass index; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg02804564 chr10:112679224 NCRNA00081;SHOC2 0.43 6.2 0.32 1.59e-9 Pancreatic cancer; LIHC cis rs7520050 0.931 rs11211213 chr1:46342517 G/A cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.35e-8 Red blood cell count;Reticulocyte count; LIHC cis rs798554 0.757 rs1182198 chr7:2862906 C/T cg19717773 chr7:2847554 GNA12 -0.46 -7.01 -0.35 1.3e-11 Height; LIHC cis rs7487075 0.619 rs10880968 chr12:46822960 C/T cg23829395 chr12:46796953 NA 0.35 6.17 0.32 1.97e-9 Itch intensity from mosquito bite; LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg22963979 chr7:1858916 MAD1L1 -0.44 -7.18 -0.36 4.48e-12 Bipolar disorder and schizophrenia; LIHC cis rs8180040 1.000 rs807810 chr3:47403892 G/A cg02527881 chr3:46936655 PTH1R 0.3 5.85 0.3 1.12e-8 Colorectal cancer; LIHC cis rs2153535 0.542 rs9505465 chr6:8510846 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.58 0.42 3.44e-16 Motion sickness; LIHC cis rs17685 0.753 rs1637051 chr7:75730659 G/A cg04610667 chr7:75704037 NA -0.33 -5.94 -0.31 6.93e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs314370 0.818 rs13245899 chr7:100497131 A/G cg10426581 chr7:100472382 SRRT 0.5 6.57 0.33 1.84e-10 Resting heart rate; LIHC cis rs1639906 0.895 rs3800926 chr7:2205956 G/A cg02951883 chr7:2050386 MAD1L1 0.57 7.58 0.38 3.26e-13 Colonoscopy-negative controls vs population controls; LIHC trans rs3780486 0.846 rs10738905 chr9:33123627 A/G cg20290983 chr6:43655470 MRPS18A 1.15 29.37 0.85 1.53e-95 IgG glycosylation; LIHC cis rs1005277 0.579 rs2474594 chr10:38426661 G/C cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2404602 0.647 rs10851892 chr15:77176491 T/C cg03037974 chr15:76606532 NA -0.59 -9.87 -0.47 2.27e-20 Blood metabolite levels; LIHC trans rs1814175 0.817 rs1988416 chr11:49932324 G/A cg18944383 chr4:111397179 ENPEP 0.27 6.92 0.35 2.29e-11 Height; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg07991479 chr17:40265765 KAT2A;DHX58 0.41 6.14 0.32 2.27e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs17376456 0.877 rs10063045 chr5:93457584 A/T cg25358565 chr5:93447407 FAM172A 1.01 7.79 0.39 8.11e-14 Diabetic retinopathy; LIHC cis rs7264396 0.790 rs3787166 chr20:34229072 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.89 -0.43 3.51e-17 Total cholesterol levels; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.66 9.67 0.46 1.03e-19 Lymphocyte counts; LIHC cis rs4555082 0.834 rs2816651 chr14:105708470 A/G cg06808227 chr14:105710500 BRF1 -0.61 -8.48 -0.42 6.72e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs4555082 0.874 rs2816625 chr14:105734565 G/A cg06808227 chr14:105710500 BRF1 -0.55 -7.17 -0.36 4.66e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs4450131 0.618 rs7075794 chr10:126338093 A/G cg20435097 chr10:126320824 FAM53B 0.6 11.28 0.52 2.61e-25 White blood cell count (basophil); LIHC cis rs6442522 0.673 rs7628975 chr3:15502130 C/T cg16303742 chr3:15540471 COLQ -0.43 -7.22 -0.36 3.49e-12 Uric acid levels; LIHC trans rs728616 0.681 rs12769764 chr10:81917113 C/G cg07377288 chr7:102004298 NA 0.51 6.24 0.32 1.27e-9 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs4665809 0.878 rs4143538 chr2:26290178 A/C cg27170947 chr2:26402098 FAM59B -0.69 -8.43 -0.41 1e-15 Gut microbiome composition (summer); LIHC cis rs9393692 0.905 rs9357004 chr6:26303319 A/G cg13736514 chr6:26305472 NA -0.37 -6.33 -0.32 7.72e-10 Educational attainment; LIHC cis rs6062302 0.522 rs3761126 chr20:62252044 C/T cg09650180 chr20:62225654 GMEB2 -0.38 -5.94 -0.31 7.04e-9 Glioblastoma; LIHC cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.4 0.45 8.18e-19 Platelet count; LIHC trans rs66887589 0.934 rs56843000 chr4:120516597 T/C cg25214090 chr10:38739885 LOC399744 -0.4 -6.56 -0.33 1.98e-10 Diastolic blood pressure; LIHC cis rs11792861 0.926 rs7046725 chr9:111882729 T/G cg05043794 chr9:111880884 C9orf5 -0.27 -6.35 -0.32 6.85e-10 Menarche (age at onset); LIHC trans rs2727020 0.521 rs10839296 chr11:49537617 T/C cg15704280 chr7:45808275 SEPT13 0.78 11.76 0.54 5e-27 Coronary artery disease; LIHC cis rs7944584 0.552 rs12361415 chr11:47474146 T/G cg20307385 chr11:47447363 PSMC3 0.87 12.09 0.55 2.82e-28 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs2932538 0.922 rs6673930 chr1:113104887 A/G cg22162597 chr1:113214053 CAPZA1 0.72 10.99 0.51 2.93e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs6714710 0.603 rs11680321 chr2:98379267 C/T cg26665480 chr2:98280029 ACTR1B 0.45 6.41 0.33 4.73e-10 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg13126279 chr21:47581558 C21orf56 -0.47 -7.78 -0.39 8.47e-14 Testicular germ cell tumor; LIHC cis rs5758511 0.633 rs5751258 chr22:42663871 C/G cg20195005 chr22:42527684 CYP2D6 0.31 5.84 0.3 1.23e-8 Birth weight; LIHC cis rs6442522 0.560 rs13092264 chr3:15514297 A/T cg16303742 chr3:15540471 COLQ 0.38 6.23 0.32 1.35e-9 Uric acid levels; LIHC cis rs7408868 0.908 rs2074619 chr19:15276919 G/A cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.68e-8 Pulse pressure; LIHC cis rs6952808 0.929 rs2280550 chr7:1976556 G/A cg20295408 chr7:1910781 MAD1L1 -0.45 -6.54 -0.33 2.28e-10 Bipolar disorder and schizophrenia; LIHC cis rs477692 0.699 rs509017 chr10:131367174 T/G cg19680672 chr10:131412579 MGMT -0.39 -5.85 -0.3 1.14e-8 Response to temozolomide; LIHC cis rs637571 0.584 rs659824 chr11:65636509 A/G cg26695010 chr11:65641043 EFEMP2 0.56 7.95 0.39 2.82e-14 Eosinophil percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04203429 chr16:29822912 PRRT2 0.49 6.71 0.34 7.96e-11 Lung function (FEV1/FVC); LIHC cis rs7937840 0.597 rs3890102 chr11:61915823 C/T cg01969543 chr11:61895209 INCENP 0.48 6.23 0.32 1.35e-9 Breast cancer; LIHC cis rs3791556 1.000 rs2411429 chr2:240113928 A/G cg03281426 chr2:240109471 HDAC4 0.42 6.29 0.32 9.44e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs17604090 0.557 rs10279965 chr7:29717082 C/G cg19413766 chr7:29689036 LOC646762 -0.61 -6.28 -0.32 1e-9 Facial emotion recognition;Facial emotion recognition (sad faces); LIHC cis rs801193 0.660 rs10950049 chr7:66230860 T/C cg11764359 chr7:65958608 NA 0.82 14.54 0.62 1.27e-37 Aortic root size; LIHC cis rs7635838 0.892 rs754015 chr3:11493945 T/C cg00170343 chr3:11313890 ATG7 0.4 6.36 0.33 6.32e-10 HDL cholesterol; LIHC cis rs7208859 0.623 rs7219361 chr17:29080393 G/A cg14067834 chr17:29058358 SUZ12P 0.64 6.4 0.33 5.11e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg12310025 chr6:25882481 NA -0.7 -8.72 -0.43 1.2e-16 Intelligence (multi-trait analysis); LIHC cis rs13256369 0.951 rs12679360 chr8:8566269 G/T cg00074818 chr8:8560427 CLDN23 -0.4 -6.59 -0.34 1.68e-10 Obesity-related traits; LIHC cis rs35110281 0.774 rs1003280 chr21:44997322 A/G cg04455712 chr21:45112962 RRP1B 0.47 8.0 0.4 2.02e-14 Mean corpuscular volume; LIHC trans rs2243480 1.000 rs2707831 chr7:66062511 G/A cg07424592 chr7:64974309 NA 0.77 8.87 0.43 4.13e-17 Diabetic kidney disease; LIHC cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg04546413 chr19:29218101 NA 0.55 10.25 0.48 1.09e-21 Methadone dose in opioid dependence; LIHC cis rs796364 0.951 rs3098341 chr2:200792498 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.16 0.44 4.71e-18 Schizophrenia; LIHC cis rs208520 0.608 rs3846803 chr6:66805743 C/A cg07460842 chr6:66804631 NA -0.84 -9.29 -0.45 1.86e-18 Exhaled nitric oxide output; LIHC cis rs57502260 0.704 rs41478448 chr11:68181621 A/G cg16797656 chr11:68205561 LRP5 0.59 7.8 0.39 7.49e-14 Total body bone mineral density (age 45-60); LIHC cis rs9309473 0.898 rs11126403 chr2:73796923 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.77 -0.34 5.56e-11 Metabolite levels; LIHC cis rs3790645 0.874 rs9438508 chr1:26893069 T/C cg23229016 chr1:26872525 RPS6KA1 0.23 5.75 0.3 2.02e-8 Glucose homeostasis traits; LIHC cis rs6545883 0.831 rs9309336 chr2:61763165 T/C cg15711740 chr2:61764176 XPO1 -0.44 -6.15 -0.32 2.12e-9 Tuberculosis; LIHC cis rs9583531 0.600 rs754599 chr13:111354788 C/A cg24331049 chr13:111365604 ING1 0.76 12.88 0.57 3.12e-31 Coronary artery disease; LIHC cis rs7582720 1.000 rs72932793 chr2:203701004 T/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.74 5.99 0.31 5.39e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4423214 0.592 rs3829251 chr11:71194559 G/A cg05163923 chr11:71159392 DHCR7 -0.58 -7.09 -0.36 7.78e-12 Vitamin D levels; LIHC cis rs4665809 0.838 rs6546780 chr2:26352857 T/C cg27170947 chr2:26402098 FAM59B -0.65 -8.22 -0.41 4.22e-15 Gut microbiome composition (summer); LIHC cis rs1395 0.744 rs11126935 chr2:27476740 G/T cg23587288 chr2:27483067 SLC30A3 -0.35 -6.56 -0.33 1.99e-10 Blood metabolite levels; LIHC cis rs12644436 0.628 rs13125634 chr4:88785001 G/A cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg09455208 chr3:40491958 NA -0.39 -7.95 -0.39 2.82e-14 Renal cell carcinoma; LIHC cis rs9911578 0.967 rs11079354 chr17:56594460 G/A cg05425664 chr17:57184151 TRIM37 0.58 8.51 0.42 5.54e-16 Intelligence (multi-trait analysis); LIHC cis rs7903847 0.642 rs10882913 chr10:99141845 C/T cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9303401 0.527 rs12946522 chr17:56768103 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.85 10.6 0.5 6.86e-23 Cognitive test performance; LIHC cis rs7208859 0.623 rs55961983 chr17:29119286 G/A cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4555082 0.874 rs78923231 chr14:105754033 C/T cg06808227 chr14:105710500 BRF1 -0.49 -5.99 -0.31 5.41e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs4141404 0.923 rs2413046 chr22:31665909 C/A cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Paclitaxel-induced neuropathy; LIHC trans rs2235573 0.527 rs139862 chr22:38351986 T/C cg19894588 chr14:64061835 NA 0.46 6.08 0.31 3.24e-9 Glioblastoma;Glioma; LIHC cis rs6088590 1.000 rs11698996 chr20:33449739 C/G cg06115741 chr20:33292138 TP53INP2 0.62 8.22 0.41 4.13e-15 Coronary artery disease; LIHC cis rs7100689 0.577 rs10749560 chr10:82092801 G/T cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg21664854 chr7:1097933 C7orf50;GPR146 0.76 5.84 0.3 1.24e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs1499614 1.000 rs2659913 chr7:66157336 T/A cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg02353165 chr6:42928485 GNMT 0.72 10.96 0.51 3.62e-24 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs13108904 0.936 rs4974540 chr4:1213463 C/T cg19318889 chr4:1322082 MAEA 0.44 6.64 0.34 1.22e-10 Obesity-related traits; LIHC cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg04025307 chr7:1156635 C7orf50 0.6 10.35 0.49 5e-22 Longevity;Endometriosis; LIHC cis rs7617773 0.779 rs11718329 chr3:48309828 C/G cg11946769 chr3:48343235 NME6 0.88 11.33 0.52 1.78e-25 Coronary artery disease; LIHC cis rs853679 0.517 rs9368552 chr6:28068426 A/G cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs7829975 0.626 rs907183 chr8:8729761 C/G cg06636001 chr8:8085503 FLJ10661 -0.39 -6.15 -0.32 2.11e-9 Mood instability; LIHC cis rs8010715 0.520 rs12435994 chr14:24589461 A/C cg23112188 chr14:24563095 PCK2 -0.32 -6.46 -0.33 3.5e-10 IgG glycosylation; LIHC cis rs9372253 0.678 rs9372251 chr6:110700656 A/G cg00083206 chr6:110721305 DDO -0.34 -6.68 -0.34 9.5e-11 Platelet distribution width; LIHC trans rs13113518 0.812 rs12500456 chr4:56427220 C/T cg15358633 chr12:38710606 ALG10B 0.44 6.31 0.32 8.71e-10 Height; LIHC cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg10217327 chr6:118973057 C6orf204 0.64 6.22 0.32 1.48e-9 Renal cell carcinoma; LIHC cis rs7659604 0.539 rs7660548 chr4:122730821 G/C cg19748678 chr4:122722346 EXOSC9 0.67 11.07 0.51 1.47e-24 Type 2 diabetes; LIHC cis rs11971779 0.680 rs28579232 chr7:139073116 C/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2836950 0.565 rs7276046 chr21:40581293 T/C cg17971929 chr21:40555470 PSMG1 -0.39 -5.93 -0.31 7.6e-9 Menarche (age at onset); LIHC cis rs4891159 0.548 rs2554830 chr18:74127702 A/G cg24786174 chr18:74118243 ZNF516 0.83 16.8 0.67 1.37e-46 Longevity; LIHC cis rs12477438 0.501 rs6708878 chr2:99801564 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg00166722 chr3:10149974 C3orf24 0.5 5.94 0.31 7e-9 Alzheimer's disease; LIHC trans rs72766638 0.895 rs11795079 chr9:136930134 T/C cg09836344 chr4:1243392 C4orf42;CTBP1 -0.58 -6.51 -0.33 2.65e-10 Mosquito bite size; LIHC cis rs561341 0.709 rs11542477 chr17:30185892 A/G cg13647721 chr17:30228624 UTP6 -0.76 -6.5 -0.33 2.87e-10 Hip circumference adjusted for BMI; LIHC cis rs965469 1.000 rs965469 chr20:3381549 T/C cg25506879 chr20:3388711 C20orf194 -0.57 -6.85 -0.35 3.38e-11 IFN-related cytopenia; LIHC cis rs6912958 0.703 rs9353483 chr6:88097180 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.4 7.84 0.39 5.75e-14 Monocyte percentage of white cells; LIHC cis rs7674212 0.539 rs6850461 chr4:104120041 C/T cg16532752 chr4:104119610 CENPE -0.46 -7.2 -0.36 3.77e-12 Type 2 diabetes; LIHC cis rs6424115 0.760 rs2999566 chr1:24051124 A/G cg15997130 chr1:24165203 NA 0.32 6.44 0.33 3.96e-10 Immature fraction of reticulocytes; LIHC cis rs5769765 0.773 rs9616751 chr22:50222236 T/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.76 -8.04 -0.4 1.43e-14 Schizophrenia; LIHC trans rs561341 0.941 rs4795664 chr17:30233467 C/T cg20587970 chr11:113659929 NA -0.74 -8.45 -0.42 8.62e-16 Hip circumference adjusted for BMI; LIHC cis rs35306767 0.903 rs12250937 chr10:900209 C/T cg26597838 chr10:835615 NA 1.17 13.67 0.59 3.07e-34 Eosinophil percentage of granulocytes; LIHC cis rs9303401 0.659 rs66514313 chr17:56714057 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs920590 0.721 rs67989257 chr8:19660278 G/A cg17834443 chr8:19674713 INTS10 0.47 6.94 0.35 2.02e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs6442522 0.606 rs3773462 chr3:15494279 G/A cg16303742 chr3:15540471 COLQ 0.39 6.44 0.33 3.96e-10 Uric acid levels; LIHC cis rs12497850 0.931 rs11920534 chr3:48937761 G/T cg06212747 chr3:49208901 KLHDC8B 0.57 7.49 0.38 5.8e-13 Parkinson's disease; LIHC cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg18404041 chr3:52824283 ITIH1 -0.5 -8.38 -0.41 1.38e-15 Bipolar disorder; LIHC cis rs916888 0.821 rs70600 chr17:44860021 C/T cg15921436 chr17:44337874 NA 0.67 6.81 0.35 4.35e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs7674212 0.541 rs4699051 chr4:104114394 T/C cg16471864 chr4:38666270 KLF3;FLJ13197 -0.44 -6.14 -0.32 2.25e-9 Type 2 diabetes; LIHC cis rs8180040 1.000 rs811115 chr3:47322133 C/T cg27129171 chr3:47204927 SETD2 0.64 11.01 0.51 2.46e-24 Colorectal cancer; LIHC cis rs8177253 1.000 rs1525892 chr3:133484712 C/T cg12373951 chr3:133503437 NA 0.68 12.14 0.55 1.83e-28 Iron status biomarkers; LIHC cis rs12478296 0.591 rs4973646 chr2:243001373 C/T cg06360820 chr2:242988706 NA 0.73 11.2 0.52 5e-25 Obesity-related traits; LIHC cis rs2455601 0.766 rs1109304 chr11:8955455 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -6.35 -0.32 6.93e-10 Schizophrenia; LIHC cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg06238570 chr21:40685208 BRWD1 0.56 6.79 0.34 4.99e-11 Cognitive function; LIHC cis rs7119 0.717 rs12898281 chr15:77786903 C/T cg17802220 chr15:77601643 NA 0.41 7.23 0.36 3.09e-12 Type 2 diabetes; LIHC cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg13395646 chr4:1353034 KIAA1530 -0.61 -8.98 -0.44 1.89e-17 Obesity-related traits; LIHC cis rs9790314 0.846 rs1478568 chr3:161014276 C/T cg03342759 chr3:160939853 NMD3 -0.72 -10.31 -0.49 7.22e-22 Morning vs. evening chronotype; LIHC cis rs72387598 1 rs72387598 chr1:45922977 CAT/C cg24296786 chr1:45957014 TESK2 -0.51 -7.33 -0.37 1.68e-12 Platelet distribution width; LIHC cis rs9818758 0.607 rs113186424 chr3:49272726 T/C cg06212747 chr3:49208901 KLHDC8B -0.65 -5.77 -0.3 1.75e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2075671 0.903 rs11979818 chr7:100293639 A/G cg16850897 chr7:100343110 ZAN 0.39 5.85 0.3 1.15e-8 Other erythrocyte phenotypes; LIHC cis rs6088580 0.634 rs6059890 chr20:33101653 G/C cg08999081 chr20:33150536 PIGU 0.67 13.45 0.59 2.07e-33 Glomerular filtration rate (creatinine); LIHC cis rs797680 0.786 rs7532195 chr1:93617403 T/G cg15093775 chr1:93646470 TMED5;CCDC18 -0.35 -6.1 -0.31 2.87e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23029100 chr15:76603787 ETFA -0.45 -6.61 -0.34 1.44e-10 Cognitive function; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15358743 chr18:56807035 SEC11C 0.42 6.19 0.32 1.71e-9 Pancreatic cancer; LIHC cis rs4423214 1.000 rs2276360 chr11:71169547 C/G cg05163923 chr11:71159392 DHCR7 0.87 13.13 0.58 3.51e-32 Vitamin D levels; LIHC cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg19318889 chr4:1322082 MAEA -0.47 -7.78 -0.39 8.4e-14 Obesity-related traits; LIHC cis rs7829975 0.572 rs7005000 chr8:8796602 A/G cg06636001 chr8:8085503 FLJ10661 -0.42 -6.6 -0.34 1.54e-10 Mood instability; LIHC trans rs8073060 0.586 rs7208672 chr17:33989759 G/A cg19694781 chr19:47549865 TMEM160 -1.25 -13.0 -0.58 1.13e-31 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs894734 0.535 rs7301643 chr12:54325796 G/T cg25024717 chr12:54324583 NA -0.38 -8.17 -0.4 6.22e-15 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC trans rs9747201 0.962 rs34016823 chr17:80095428 G/T cg07393940 chr7:158741817 NA -0.57 -6.91 -0.35 2.43e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs16944613 0.510 rs4476150 chr15:91147214 G/A cg26821196 chr15:91095069 CRTC3 0.35 6.29 0.32 9.71e-10 Colorectal cancer; LIHC trans rs2209875 1.000 rs1305024 chr9:91809082 T/C cg26057616 chr1:222234397 NA 0.36 6.04 0.31 3.93e-9 Pelvic organ prolapse (moderate/severe); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg12833168 chr14:39856160 NA 0.47 6.35 0.32 6.73e-10 Hepatitis; LIHC cis rs2070488 0.965 rs7642472 chr3:38525567 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.95 0.65 3.35e-43 Electrocardiographic conduction measures; LIHC cis rs9303280 0.936 rs12950209 chr17:38049102 T/C cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.72 0.3 2.3e-8 Self-reported allergy; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg03861428 chr1:17380702 SDHB -0.49 -6.23 -0.32 1.37e-9 Hip circumference; LIHC cis rs2273156 1.000 rs12897612 chr14:35471147 C/T cg16230307 chr14:35515116 FAM177A1 -0.41 -6.05 -0.31 3.88e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs60871478 1.000 rs4720917 chr7:806998 C/G cg27478167 chr7:817139 HEATR2 -0.41 -5.83 -0.3 1.32e-8 Cerebrospinal P-tau181p levels; LIHC cis rs7107174 1.000 rs2244508 chr11:77948515 T/A cg02023728 chr11:77925099 USP35 0.49 9.24 0.45 2.6e-18 Testicular germ cell tumor; LIHC cis rs2228479 0.717 rs11644967 chr16:89806614 T/A cg06558623 chr16:89946397 TCF25 0.82 11.39 0.52 1.06e-25 Skin colour saturation; LIHC cis rs9470366 0.883 rs9462207 chr6:36627599 T/C cg08179530 chr6:36648295 CDKN1A 0.57 6.97 0.35 1.63e-11 QRS duration; LIHC cis rs2050392 0.624 rs303435 chr10:30731491 T/C cg18806716 chr10:30721971 MAP3K8 -0.42 -6.06 -0.31 3.53e-9 Inflammatory bowel disease; LIHC cis rs7917772 0.503 rs56397707 chr10:104302693 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 12.7 0.57 1.58e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs425277 1.000 rs381664 chr1:2088104 A/G cg24578937 chr1:2090814 PRKCZ 0.51 9.17 0.44 4.39e-18 Height; LIHC cis rs6964587 0.541 rs6947170 chr7:91451471 A/G cg17063962 chr7:91808500 NA 0.63 10.85 0.51 9.14e-24 Breast cancer; LIHC cis rs9467160 0.520 rs9356934 chr6:24442171 C/T cg20631270 chr6:24437470 GPLD1 0.4 6.01 0.31 4.74e-9 Liver enzyme levels; LIHC trans rs12478296 0.892 rs60042638 chr2:243038707 G/A cg01596870 chr19:55963115 NA -0.63 -8.33 -0.41 1.95e-15 Obesity-related traits; LIHC cis rs2574704 0.924 rs2574725 chr3:11657017 C/T cg15876825 chr3:11651881 VGLL4 0.49 8.13 0.4 8.18e-15 Body mass index; LIHC cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.84 8.02 0.4 1.73e-14 Platelet count; LIHC cis rs637571 0.654 rs1058068 chr11:65667796 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.48 7.45 0.37 7.49e-13 Eosinophil percentage of white cells; LIHC cis rs6456156 0.565 rs12529959 chr6:167469292 T/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.71 -0.43 1.28e-16 Primary biliary cholangitis; LIHC cis rs2153535 0.580 rs1120392 chr6:8487053 C/A cg23788917 chr6:8435910 SLC35B3 0.59 8.47 0.42 7.56e-16 Motion sickness; LIHC cis rs10508774 0.810 rs72795559 chr10:32872971 A/G cg01819863 chr10:32635814 EPC1 0.6 5.82 0.3 1.38e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs15676 0.947 rs2805103 chr9:131598897 T/A cg00228799 chr9:131580591 ENDOG 0.45 6.79 0.34 5.13e-11 Blood metabolite levels; LIHC cis rs655641 1.000 rs670606 chr11:85698598 G/A cg09030501 chr11:85779252 PICALM -0.51 -6.11 -0.31 2.76e-9 Platelet count; LIHC cis rs3789045 0.774 rs12028476 chr1:204476361 G/A cg17419461 chr1:204415978 PIK3C2B -0.39 -5.93 -0.31 7.24e-9 Educational attainment (college completion); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg17114402 chr2:97778470 ANKRD36 0.43 6.22 0.32 1.43e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6815814 0.950 rs73236615 chr4:38786869 G/T cg06935464 chr4:38784597 TLR10 0.55 8.98 0.44 1.91e-17 Breast cancer; LIHC cis rs7264396 0.836 rs6058276 chr20:34187728 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.54 -8.65 -0.42 2.1e-16 Total cholesterol levels; LIHC trans rs916888 0.779 rs430685 chr17:44859148 T/C cg16836995 chr17:43662488 NA 0.67 6.88 0.35 2.79e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs17401966 0.931 rs12137880 chr1:10388620 T/C cg19773385 chr1:10388646 KIF1B -0.4 -6.96 -0.35 1.7e-11 Hepatocellular carcinoma; LIHC cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC cis rs12995491 0.731 rs56188884 chr2:88508657 G/A cg04511125 chr2:88470314 THNSL2 -0.47 -6.91 -0.35 2.4e-11 Response to metformin (IC50); LIHC cis rs7592578 0.679 rs62181018 chr2:191323295 C/T cg27211696 chr2:191398769 TMEM194B -0.52 -6.82 -0.35 4.16e-11 Diastolic blood pressure; LIHC cis rs7618501 1.000 rs7431106 chr3:49808374 G/A cg21467203 chr3:49911342 NA -0.41 -7.07 -0.36 9e-12 Intelligence (multi-trait analysis); LIHC cis rs951366 0.789 rs823137 chr1:205738302 C/T cg07157834 chr1:205819609 PM20D1 0.68 10.54 0.5 1.16e-22 Menarche (age at onset); LIHC trans rs10510776 0.875 rs11710973 chr3:55217512 C/T cg10385411 chr19:48897143 GRIN2D 0.44 6.2 0.32 1.62e-9 Cancer; LIHC cis rs7666738 0.657 rs13102002 chr4:98617794 T/C cg05340658 chr4:99064831 C4orf37 0.51 5.71 0.3 2.41e-8 Colonoscopy-negative controls vs population controls; LIHC cis rs2274273 0.870 rs10142547 chr14:55763963 T/C cg01864836 chr14:55583639 NA -0.4 -7.45 -0.37 7.51e-13 Protein biomarker; LIHC cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04998419 chr1:40626967 RLF -0.55 -6.51 -0.33 2.65e-10 Systolic blood pressure; LIHC cis rs710216 0.957 rs2886876 chr1:43432741 A/G cg03128534 chr1:43423976 SLC2A1 -0.47 -5.94 -0.31 6.89e-9 Red cell distribution width; LIHC cis rs1046896 0.520 rs9895409 chr17:80902719 C/T cg02711726 chr17:80685570 FN3KRP -0.41 -7.62 -0.38 2.5e-13 Glycated hemoglobin levels; LIHC cis rs870825 0.616 rs56844261 chr4:185632478 T/C cg04058563 chr4:185651563 MLF1IP 0.7 7.36 0.37 1.36e-12 Blood protein levels; LIHC cis rs2070488 0.965 rs9829192 chr3:38569463 G/T cg24069376 chr3:38537580 EXOG -0.38 -6.86 -0.35 3.16e-11 Electrocardiographic conduction measures; LIHC cis rs3770081 1.000 rs74607112 chr2:86305534 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.99 -11.51 -0.53 4.05e-26 Facial emotion recognition (sad faces); LIHC cis rs4147929 0.532 rs4147932 chr19:1064485 C/T cg05372495 chr19:1063624 ABCA7 -0.41 -6.6 -0.34 1.55e-10 Alzheimer's disease (late onset); LIHC cis rs72843506 0.586 rs73296067 chr17:19880301 G/A cg12065943 chr17:19881925 AKAP10 -0.38 -6.42 -0.33 4.54e-10 Schizophrenia; LIHC cis rs8060686 0.563 rs118005841 chr16:68157562 A/T cg09835421 chr16:68378352 PRMT7 -0.5 -5.78 -0.3 1.7e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.0 9.46 0.46 5.3e-19 Platelet count; LIHC cis rs950776 0.593 rs621849 chr15:78872861 G/A cg06917634 chr15:78832804 PSMA4 -0.62 -8.45 -0.42 8.54e-16 Sudden cardiac arrest; LIHC cis rs1816752 1.000 rs7326932 chr13:25004493 A/T cg22771759 chr13:24902376 NA 0.33 6.75 0.34 6.21e-11 Obesity-related traits; LIHC cis rs7508 0.511 rs438818 chr8:17899561 A/G cg04898035 chr8:17640624 MTUS1 -0.34 -5.99 -0.31 5.2e-9 Atrial fibrillation; LIHC cis rs858239 0.601 rs6980224 chr7:23149137 C/T cg23682824 chr7:23144976 KLHL7 0.44 6.62 0.34 1.39e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs12464559 0.649 rs9288006 chr2:152661831 G/A cg01189475 chr2:152685088 ARL5A 0.63 7.38 0.37 1.17e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7945718 0.967 rs10741602 chr11:12761699 A/T cg25843174 chr11:12811716 TEAD1 0.36 8.27 0.41 3.07e-15 Educational attainment (years of education); LIHC cis rs12477438 0.798 rs9679602 chr2:99577827 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.77 9.82 0.47 3.2e-20 Chronic sinus infection; LIHC cis rs9818758 0.607 rs11719220 chr3:49245201 A/G cg00383909 chr3:49044727 WDR6 0.8 6.67 0.34 1.05e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.44e-8 Alzheimer's disease; LIHC cis rs9457247 0.663 rs9295384 chr6:167448113 T/A cg07741184 chr6:167504864 NA 0.26 6.01 0.31 4.87e-9 Crohn's disease; LIHC cis rs716804 0.740 rs10500724 chr11:10302016 A/G cg01453529 chr11:10209919 SBF2 0.29 5.81 0.3 1.45e-8 Neuroticism; LIHC cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.69 0.38 1.61e-13 Prudent dietary pattern; LIHC cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg21724239 chr8:58056113 NA 0.63 7.33 0.37 1.62e-12 Developmental language disorder (linguistic errors); LIHC cis rs10089 1.000 rs9968597 chr5:127455383 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.55 6.8 0.34 4.77e-11 Ileal carcinoids; LIHC cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg00656387 chr3:40428638 ENTPD3 -0.5 -8.53 -0.42 4.94e-16 Renal cell carcinoma; LIHC trans rs7618501 0.633 rs9853222 chr3:50022926 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.58 9.51 0.46 3.49e-19 Intelligence (multi-trait analysis); LIHC cis rs7592578 0.508 rs55919641 chr2:191265414 G/A cg10560079 chr2:191398806 TMEM194B -0.71 -10.18 -0.48 1.89e-21 Diastolic blood pressure; LIHC cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg00149659 chr3:10157352 C3orf10 0.64 6.91 0.35 2.31e-11 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14347670 chr6:41908995 CCND3 0.47 7.12 0.36 6.45e-12 Pancreatic cancer; LIHC cis rs62458065 0.513 rs9655340 chr7:32535920 A/G cg20159608 chr7:32802032 NA 0.48 5.82 0.3 1.35e-8 Metabolite levels (HVA/MHPG ratio); LIHC cis rs2404602 0.692 rs35395069 chr15:76986334 C/T cg23625390 chr15:77176239 SCAPER 0.36 5.94 0.31 6.92e-9 Blood metabolite levels; LIHC cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg04013166 chr16:89971882 TCF25 0.64 8.96 0.44 2.1e-17 Skin colour saturation; LIHC cis rs2228479 0.850 rs11646766 chr16:89838578 A/T cg00800038 chr16:89945340 TCF25 -0.63 -9.38 -0.45 9.33e-19 Skin colour saturation; LIHC cis rs9309473 0.950 rs1052162 chr2:73829372 A/G cg20560298 chr2:73613845 ALMS1 0.55 6.88 0.35 2.82e-11 Metabolite levels; LIHC cis rs9640161 0.659 rs11974980 chr7:150009838 C/T cg21361702 chr7:150065534 REPIN1 0.48 6.63 0.34 1.29e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs12220238 0.841 rs11000952 chr10:76037336 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 5.96 0.31 6.35e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs787274 1.000 rs787275 chr9:115550523 C/G cg13803584 chr9:115635662 SNX30 -0.6 -6.41 -0.33 4.77e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg23344412 chr5:32602844 SUB1 -0.3 -7.16 -0.36 4.93e-12 Calcium levels; LIHC cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg06481639 chr22:41940642 POLR3H -0.61 -6.0 -0.31 4.9e-9 Vitiligo; LIHC cis rs3789045 0.826 rs55979051 chr1:204567041 A/G cg17419461 chr1:204415978 PIK3C2B -0.39 -6.03 -0.31 4.34e-9 Educational attainment (college completion); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17157516 chr1:35332203 DLGAP3 0.45 6.68 0.34 9.43e-11 Pancreatic cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg10183001 chr12:51318430 METTL7A -0.41 -6.24 -0.32 1.26e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2439831 0.850 rs28564774 chr15:44125475 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.69 0.43 1.58e-16 Lung cancer in ever smokers; LIHC cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg24884572 chr19:58661833 ZNF329 0.96 7.48 0.37 6.44e-13 Cholesterol, total; LIHC trans rs4332037 0.906 rs62442903 chr7:1953416 G/A cg11693508 chr17:37793320 STARD3 0.7 7.38 0.37 1.24e-12 Bipolar disorder; LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg08219700 chr8:58056026 NA 0.52 7.15 0.36 5.24e-12 Developmental language disorder (linguistic errors); LIHC cis rs4319547 0.741 rs4758644 chr12:122943915 A/C cg05707623 chr12:122985044 ZCCHC8 -0.59 -7.99 -0.4 2.14e-14 Body mass index; LIHC cis rs4665809 1.000 rs10182857 chr2:26344411 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.7 -8.69 -0.43 1.56e-16 Gut microbiome composition (summer); LIHC cis rs34779708 0.931 rs17582416 chr10:35287650 A/C cg03585969 chr10:35415529 CREM 0.66 9.11 0.44 7.04e-18 Inflammatory bowel disease;Crohn's disease; LIHC trans rs11088226 0.692 rs7510418 chr21:33890258 G/A cg09050820 chr6:167586206 TCP10L2 0.44 6.49 0.33 3.03e-10 Gastritis; LIHC cis rs7246657 0.882 rs10422667 chr19:37937876 T/C cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs15676 0.783 rs10819442 chr9:131564750 C/G cg00228799 chr9:131580591 ENDOG -0.48 -6.8 -0.34 4.79e-11 Blood metabolite levels; LIHC cis rs10791323 0.521 rs10894756 chr11:133745852 G/A cg06766960 chr11:133703094 NA -0.41 -6.14 -0.32 2.31e-9 Childhood ear infection; LIHC cis rs1400745 0.756 rs10136352 chr14:35334555 C/T cg16230307 chr14:35515116 FAM177A1 0.37 6.08 0.31 3.3e-9 Monocyte count; LIHC cis rs11626933 1.000 rs59905513 chr14:90749638 T/C cg07150772 chr14:90864620 CALM1 -0.42 -5.87 -0.3 1.03e-8 Gut microbiota (bacterial taxa); LIHC cis rs1538970 0.847 rs781230 chr1:45880751 C/T cg15605315 chr1:45957053 TESK2 0.44 5.92 0.3 7.91e-9 Platelet count; LIHC trans rs6489882 0.902 rs10774679 chr12:113374748 A/G cg10175203 chr3:128143634 NA -0.38 -6.12 -0.31 2.63e-9 Chronic lymphocytic leukemia; LIHC cis rs7772486 0.875 rs9403763 chr6:146357655 A/G cg23711669 chr6:146136114 FBXO30 0.66 11.76 0.54 4.95e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs4409675 0.597 rs1467464 chr1:28211650 T/C cg23691781 chr1:28212827 C1orf38 0.31 7.43 0.37 8.49e-13 Corneal astigmatism; LIHC cis rs67460515 0.892 rs4856769 chr3:161004549 C/A cg17135325 chr3:160939158 NMD3 0.54 7.42 0.37 9.21e-13 Parkinson's disease; LIHC cis rs3749237 0.595 rs11130199 chr3:49538799 T/C cg06212747 chr3:49208901 KLHDC8B 0.43 5.75 0.3 1.97e-8 Resting heart rate; LIHC trans rs561341 0.883 rs7219239 chr17:30212016 A/G cg20587970 chr11:113659929 NA 0.72 8.17 0.4 6.16e-15 Hip circumference adjusted for BMI; LIHC cis rs739401 0.619 rs10766482 chr11:2961600 C/T cg20651018 chr11:3035856 CARS -0.35 -5.94 -0.31 6.86e-9 Longevity; LIHC cis rs7106204 0.609 rs12788920 chr11:24284514 C/T ch.11.24196551F chr11:24239977 NA 0.67 6.08 0.31 3.21e-9 Response to Homoharringtonine (cytotoxicity); LIHC cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.56 -7.93 -0.39 3.19e-14 Lymphocyte counts; LIHC trans rs61931739 0.534 rs1912773 chr12:34097401 T/C cg26384229 chr12:38710491 ALG10B 0.5 6.9 0.35 2.59e-11 Morning vs. evening chronotype; LIHC cis rs72627123 0.500 rs7359018 chr14:74521008 T/C cg12022184 chr14:74485813 ENTPD5;C14orf45 0.49 6.72 0.34 7.7e-11 Morning vs. evening chronotype; LIHC cis rs12477438 0.765 rs7605734 chr2:99644068 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.56 -0.5 9.46e-23 Chronic sinus infection; LIHC cis rs4819052 0.565 rs35776291 chr21:46706142 T/C cg22633049 chr21:46681294 NA -0.33 -5.97 -0.31 5.86e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs714027 0.525 rs6006274 chr22:30232843 C/T cg01021169 chr22:30184971 ASCC2 -0.35 -6.34 -0.32 7.06e-10 Lymphocyte counts; LIHC cis rs9522267 0.535 rs7326875 chr13:112236231 C/T cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg11062466 chr8:58055876 NA 0.52 7.45 0.37 7.76e-13 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18864164 chr10:115934049 MIR2110;C10orf118 0.42 6.83 0.35 3.84e-11 Cognitive function; LIHC cis rs6089584 0.888 rs6061982 chr20:60620673 C/T cg06108461 chr20:60628389 TAF4 -1.0 -17.77 -0.69 1.67e-50 Body mass index; LIHC cis rs5753618 0.509 rs5749224 chr22:31558549 C/T cg22777020 chr22:31556080 RNF185 -0.56 -6.4 -0.33 5.2400000000000005e-10 Colorectal cancer; LIHC cis rs7727544 0.684 rs272869 chr5:131677997 A/G cg24060327 chr5:131705240 SLC22A5 -0.58 -8.43 -0.41 9.98e-16 Blood metabolite levels; LIHC cis rs3096299 0.754 rs3102382 chr16:89409742 C/G cg06640241 chr16:89574553 SPG7 0.39 5.88 0.3 9.83e-9 Multiple myeloma (IgH translocation); LIHC cis rs9303401 0.614 rs35057477 chr17:57097064 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.94 13.02 0.58 9.58e-32 Cognitive test performance; LIHC cis rs4774899 0.872 rs10518895 chr15:57404113 A/T cg19613905 chr15:56757180 MNS1 -0.38 -5.76 -0.3 1.84e-8 Urinary tract infection frequency; LIHC cis rs7666738 0.576 rs7660951 chr4:98651581 T/A cg05340658 chr4:99064831 C4orf37 0.5 6.48 0.33 3.16e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs6500602 0.627 rs863501 chr16:4588394 G/C cg08645402 chr16:4508243 NA -0.34 -5.9 -0.3 8.76e-9 Schizophrenia; LIHC cis rs3796619 1.000 rs11247973 chr4:1094314 G/A cg18657303 chr4:1051139 NA 0.34 5.82 0.3 1.37e-8 Recombination rate (males); LIHC cis rs4788570 0.566 rs8051439 chr16:71495793 A/T cg06353428 chr16:71660113 MARVELD3 -1.06 -10.0 -0.48 8.31e-21 Intelligence (multi-trait analysis); LIHC cis rs2816062 0.813 rs2745321 chr1:18889198 G/C cg18795169 chr1:18902165 NA -0.77 -16.96 -0.68 2.94e-47 Urate levels in lean individuals; LIHC cis rs1003719 0.612 rs2835652 chr21:38557408 G/T cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.72 -0.5 2.65e-23 Eye color traits; LIHC cis rs17826219 0.500 rs2449749 chr17:29078298 C/T cg13385521 chr17:29058706 SUZ12P 0.81 7.96 0.4 2.64e-14 Body mass index; LIHC cis rs7945718 0.621 rs7931934 chr11:12679245 T/G cg25843174 chr11:12811716 TEAD1 0.34 7.87 0.39 4.59e-14 Educational attainment (years of education); LIHC cis rs2153535 0.580 rs1932285 chr6:8477719 T/G cg23788917 chr6:8435910 SLC35B3 0.6 8.64 0.42 2.24e-16 Motion sickness; LIHC cis rs8060686 0.641 rs73612222 chr16:68216072 A/G cg05110241 chr16:68378359 PRMT7 -0.58 -6.6 -0.34 1.55e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs4700695 0.764 rs36299 chr5:65348120 G/T cg21114390 chr5:65439923 SFRS12 0.45 5.89 0.3 9.42e-9 Facial morphology (factor 19); LIHC trans rs2739330 0.761 rs5760176 chr22:24402321 A/G cg06437703 chr8:37914619 EIF4EBP1 0.81 13.79 0.6 1.07e-34 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs35306767 0.761 rs11253560 chr10:1047226 T/G cg20503657 chr10:835505 NA 0.83 7.99 0.4 2.07e-14 Eosinophil percentage of granulocytes; LIHC cis rs4906332 1.000 rs35126287 chr14:103959432 A/G cg04998671 chr14:104000505 TRMT61A -0.46 -6.26 -0.32 1.17e-9 Coronary artery disease; LIHC cis rs3780378 0.870 rs7034878 chr9:5058991 G/T cg02405213 chr9:5042618 JAK2 0.45 7.98 0.4 2.21e-14 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs9733 0.519 rs72704603 chr1:150707992 C/T cg17724175 chr1:150552817 MCL1 0.49 9.89 0.47 1.92e-20 Tonsillectomy; LIHC cis rs12497850 0.931 rs7623023 chr3:48914238 G/A cg07636037 chr3:49044803 WDR6 0.91 16.39 0.66 5.92e-45 Parkinson's disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg15545624 chr1:61516555 NA 0.46 6.04 0.31 4.11e-9 Hepatitis; LIHC trans rs1814175 0.565 rs4881721 chr11:49761851 G/A cg03929089 chr4:120376271 NA -0.59 -9.92 -0.47 1.55e-20 Height; LIHC cis rs9911578 0.967 rs12938821 chr17:56959422 T/C cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs8062405 0.690 rs762634 chr16:28603335 T/C cg16576597 chr16:28551801 NUPR1 0.47 6.99 0.35 1.43e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8017423 0.935 rs2104704 chr14:90696609 A/G cg04374321 chr14:90722782 PSMC1 -0.75 -14.35 -0.61 7.12e-37 Mortality in heart failure; LIHC cis rs17106184 1.000 rs72898950 chr1:50961221 T/C cg07174182 chr1:51127561 FAF1 -0.59 -6.64 -0.34 1.23e-10 Type 2 diabetes; LIHC cis rs4319547 0.626 rs12423420 chr12:122938466 G/A cg23029597 chr12:123009494 RSRC2 -0.46 -6.68 -0.34 9.64e-11 Body mass index; LIHC cis rs796364 0.906 rs281766 chr2:200820505 T/G cg12253985 chr2:200820533 C2orf60;C2orf47 0.8 9.56 0.46 2.32e-19 Schizophrenia; LIHC cis rs9790314 0.846 rs6441371 chr3:161008727 C/A cg03342759 chr3:160939853 NMD3 -0.72 -9.21 -0.45 3.3e-18 Morning vs. evening chronotype; LIHC cis rs875971 0.660 rs801211 chr7:66015689 T/G cg00343986 chr7:65444356 GUSB -0.4 -6.05 -0.31 3.88e-9 Aortic root size; LIHC cis rs8141529 0.764 rs5752809 chr22:29225500 G/A cg02153584 chr22:29168773 CCDC117 0.58 9.27 0.45 2.11e-18 Lymphocyte counts; LIHC cis rs831571 0.519 rs13059603 chr3:63827381 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.78 11.72 0.54 7.02e-27 Type 2 diabetes; LIHC cis rs600806 0.778 rs4970766 chr1:110013955 A/G cg16275483 chr1:110013120 SYPL2 0.45 5.74 0.3 2.1e-8 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.921 rs8137373 chr22:41729216 A/G cg06634786 chr22:41940651 POLR3H 0.66 7.58 0.38 3.34e-13 Vitiligo; LIHC cis rs7772486 0.624 rs6930154 chr6:146025662 C/T cg05347473 chr6:146136440 FBXO30 -0.35 -5.81 -0.3 1.46e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs12479064 0.724 rs3792143 chr2:100057020 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.7 -8.42 -0.41 1.05e-15 Chronic sinus infection; LIHC cis rs9640161 0.750 rs4395803 chr7:150025367 A/C cg27494647 chr7:150038898 RARRES2 0.32 5.81 0.3 1.47e-8 Blood protein levels;Circulating chemerin levels; LIHC cis rs11711311 1.000 rs7622403 chr3:113472434 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.37 6.75 0.34 6.45e-11 IgG glycosylation; LIHC cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg05665937 chr4:1216051 CTBP1 0.45 6.08 0.31 3.19e-9 Obesity-related traits; LIHC trans rs875971 0.965 rs10267430 chr7:65743023 G/T cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.16e-10 Aortic root size; LIHC cis rs4689592 0.503 rs59640165 chr4:7051661 G/A cg02503808 chr4:7069936 GRPEL1 -0.76 -10.49 -0.49 1.69e-22 Monocyte percentage of white cells; LIHC cis rs875971 0.862 rs7796162 chr7:65745758 T/C cg18876405 chr7:65276391 NA -0.34 -6.24 -0.32 1.29e-9 Aortic root size; LIHC cis rs4713118 0.824 rs9468229 chr6:27750086 G/A cg20933634 chr6:27740509 NA 0.46 5.96 0.31 6.28e-9 Parkinson's disease; LIHC cis rs7904368 0.806 rs7900527 chr10:16857992 C/G cg14835575 chr10:16859367 RSU1 0.67 9.36 0.45 1.07e-18 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs8180040 0.726 rs7610636 chr3:47064436 A/C cg27129171 chr3:47204927 SETD2 -0.59 -10.03 -0.48 6.5e-21 Colorectal cancer; LIHC cis rs73001065 0.892 rs58542926 chr19:19379549 C/T cg03709012 chr19:19516395 GATAD2A 0.78 6.08 0.31 3.16e-9 LDL cholesterol; LIHC cis rs2845885 0.793 rs35927325 chr11:63882495 C/T cg18375707 chr11:64034959 PLCB3 -0.68 -9.8 -0.47 3.68e-20 Body mass index; LIHC cis rs10751667 0.600 rs10751672 chr11:948712 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.94 -0.63 3.24e-39 Alzheimer's disease (late onset); LIHC cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg23149560 chr2:74406255 MOBKL1B 0.41 5.78 0.3 1.64e-8 Gestational age at birth (maternal effect); LIHC cis rs7772486 0.875 rs2474356 chr6:146296798 G/A cg05347473 chr6:146136440 FBXO30 0.36 5.81 0.3 1.45e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs7618501 1.000 rs7374183 chr3:49785133 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.81 -0.63 1.14e-38 Intelligence (multi-trait analysis); LIHC trans rs1728785 0.786 rs1728770 chr16:68564124 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.08 0.31 3.27e-9 Ulcerative colitis; LIHC trans rs16975050 0.793 rs112983094 chr18:38980631 A/C cg10554439 chr7:52344545 NA 0.41 6.06 0.31 3.65e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs2777491 1.000 rs7168177 chr15:41715585 A/G cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.3 -0.45 1.69e-18 Ulcerative colitis; LIHC trans rs6600671 0.902 rs2222371 chr1:121289118 T/C cg09829573 chr1:144692074 NBPF9 0.41 6.89 0.35 2.73e-11 Hip geometry; LIHC cis rs7903847 0.619 rs9888116 chr10:99159482 G/A cg06359132 chr10:99160096 RRP12 -0.41 -6.41 -0.33 4.83e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs765787 0.530 rs1706837 chr15:45519036 A/G cg24006582 chr15:45444508 DUOX1 -0.52 -7.56 -0.38 3.69e-13 Uric acid levels; LIHC cis rs881375 0.631 rs10739577 chr9:123668854 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 6.64 0.34 1.2e-10 Rheumatoid arthritis; LIHC cis rs2991971 0.810 rs12119202 chr1:45925931 A/T cg15605315 chr1:45957053 TESK2 -0.49 -7.06 -0.36 9.31e-12 High light scatter reticulocyte count; LIHC cis rs7953508 0.506 rs768775 chr12:93968197 T/C cg18151635 chr12:93972918 NA -0.51 -8.58 -0.42 3.4e-16 Pubertal anthropometrics; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg14926340 chr8:22225159 SLC39A14 -0.59 -6.56 -0.33 1.94e-10 Preeclampsia; LIHC cis rs1801251 0.963 rs13424351 chr2:233573629 A/G cg08000102 chr2:233561755 GIGYF2 0.75 11.13 0.52 9.01e-25 Coronary artery disease; LIHC cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg10802521 chr3:52805072 NEK4 -0.45 -7.66 -0.38 1.96e-13 Electroencephalogram traits; LIHC cis rs17685 0.712 rs10271413 chr7:75754858 G/A cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.82e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6708331 0.540 rs28623550 chr2:70366392 T/C cg01613454 chr2:70366299 NA 0.38 6.2 0.32 1.59e-9 Obesity-related traits; LIHC cis rs7089973 0.624 rs10885614 chr10:116609098 C/T cg03647239 chr10:116582469 FAM160B1 0.45 6.63 0.34 1.32e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs6502050 0.799 rs8082355 chr17:80120316 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.99 -0.31 5.35e-9 Life satisfaction; LIHC trans rs72960926 0.744 rs72950570 chr6:74913740 T/C cg07247405 chr1:2484626 LOC115110 0.54 6.2 0.32 1.62e-9 Metabolite levels (MHPG); LIHC cis rs4555082 0.874 rs2816612 chr14:105723103 C/T cg10792982 chr14:105748885 BRF1 0.45 6.03 0.31 4.22e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9868809 0.772 rs2286651 chr3:48694147 G/A cg07636037 chr3:49044803 WDR6 -0.64 -7.21 -0.36 3.65e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs4891159 0.527 rs34956524 chr18:74130480 A/G cg24786174 chr18:74118243 ZNF516 0.83 17.32 0.68 1.06e-48 Longevity; LIHC cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg06634786 chr22:41940651 POLR3H -0.83 -9.04 -0.44 1.15e-17 Vitiligo; LIHC cis rs16828019 0.852 rs34286980 chr1:41608389 A/G cg03387723 chr1:41708464 SCMH1 -0.45 -7.22 -0.36 3.37e-12 Intelligence (multi-trait analysis); LIHC cis rs9921222 0.597 rs7193109 chr16:413523 T/G cg12437481 chr16:420112 MRPL28 -0.71 -10.9 -0.51 6.24e-24 Bone mineral density (spine);Bone mineral density; LIHC cis rs9303401 0.659 rs62083362 chr17:56846464 A/G cg25039879 chr17:56429692 SUPT4H1 0.77 8.91 0.43 3e-17 Cognitive test performance; LIHC cis rs17376456 0.877 rs10052428 chr5:93476530 T/C cg25358565 chr5:93447407 FAM172A 1.09 10.02 0.48 7.05e-21 Diabetic retinopathy; LIHC cis rs4803468 1.000 rs284650 chr19:41927129 A/G cg09537434 chr19:41945824 ATP5SL -1.03 -21.43 -0.76 3.5e-65 Height; LIHC cis rs4319547 0.956 rs10773302 chr12:123043145 G/T cg05707623 chr12:122985044 ZCCHC8 -0.6 -7.9 -0.39 3.82e-14 Body mass index; LIHC cis rs9326248 1.000 rs664971 chr11:117070857 A/G cg26566898 chr11:117069891 TAGLN -0.5 -7.8 -0.39 7.66e-14 Blood protein levels; LIHC cis rs7914558 0.966 rs7921574 chr10:104840970 T/C cg15744005 chr10:104629667 AS3MT -0.37 -8.39 -0.41 1.29e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2576037 0.542 rs4630643 chr18:44508142 G/A cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 10.38 0.49 3.87e-22 Personality dimensions; LIHC cis rs709400 0.628 rs3783394 chr14:103858673 G/A cg26031613 chr14:104095156 KLC1 0.79 9.91 0.47 1.65e-20 Body mass index; LIHC cis rs2777491 1.000 rs316605 chr15:41771591 G/A cg18705301 chr15:41695430 NDUFAF1 -0.61 -9.15 -0.44 5.28e-18 Ulcerative colitis; LIHC cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg04267008 chr7:1944627 MAD1L1 -0.6 -9.21 -0.45 3.26e-18 Bipolar disorder and schizophrenia; LIHC cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.15e-9 Menopause (age at onset); LIHC cis rs10193935 1.000 rs13399869 chr2:42386041 C/G cg27598129 chr2:42591480 NA -0.73 -11.32 -0.52 1.89e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs35110281 0.693 rs2251253 chr21:45092257 T/A cg21573476 chr21:45109991 RRP1B -0.57 -10.98 -0.51 3.03e-24 Mean corpuscular volume; LIHC trans rs2209875 1.000 rs2873094 chr9:91800274 G/T cg26057616 chr1:222234397 NA -0.36 -6.04 -0.31 4.06e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg26338869 chr17:61819248 STRADA 0.58 8.63 0.42 2.29e-16 Prudent dietary pattern; LIHC cis rs4407350 0.967 rs5765722 chr22:44921063 G/A cg11695653 chr22:44894386 LDOC1L -0.37 -6.11 -0.31 2.64e-9 Intelligence (multi-trait analysis); LIHC cis rs9309473 1.000 rs7604682 chr2:73788026 G/A cg20560298 chr2:73613845 ALMS1 -0.54 -6.77 -0.34 5.56e-11 Metabolite levels; LIHC cis rs7772486 0.790 rs6924159 chr6:146267873 A/G cg05347473 chr6:146136440 FBXO30 -0.38 -6.08 -0.31 3.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6545883 0.965 rs10186325 chr2:61757721 G/T cg14146966 chr2:61757674 XPO1 0.53 9.66 0.46 1.07e-19 Tuberculosis; LIHC cis rs344364 0.511 rs1657133 chr16:1950300 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.27 -0.37 2.54e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs11112613 0.713 rs4015312 chr12:105948757 A/G cg03607813 chr12:105948248 NA 0.65 12.21 0.55 1.06e-28 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7927592 0.913 rs6591340 chr11:68297636 A/G cg20283391 chr11:68216788 NA -0.52 -7.79 -0.39 8.32e-14 Total body bone mineral density; LIHC cis rs4780401 0.967 rs11075011 chr16:11828282 T/A cg01061890 chr16:11836724 TXNDC11 -0.42 -6.07 -0.31 3.34e-9 Rheumatoid arthritis; LIHC cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg11764359 chr7:65958608 NA 0.59 6.26 0.32 1.18e-9 Diabetic kidney disease; LIHC cis rs929354 0.772 rs3802123 chr7:156970641 G/A cg17757837 chr7:157058334 UBE3C 0.76 11.93 0.54 1.13e-27 Body mass index; LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.29 0.55 5.3e-29 Prudent dietary pattern; LIHC cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg10130564 chr11:117069849 TAGLN -0.35 -5.97 -0.31 5.95e-9 Blood protein levels; LIHC cis rs668210 0.947 rs610497 chr11:65765551 C/T cg02202077 chr11:65769826 EIF1AD;BANF1 0.54 6.7 0.34 8.73e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs459482 1.000 rs459498 chr21:42795027 G/A cg14166395 chr21:42792516 MX1 0.67 9.85 0.47 2.53e-20 IgG glycosylation; LIHC cis rs9303401 0.614 rs34920953 chr17:56589406 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.95 12.84 0.57 4.49e-31 Cognitive test performance; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg12525736 chr1:228269915 ARF1 -0.47 -7.0 -0.35 1.37e-11 Alopecia areata; LIHC cis rs4689592 0.503 rs4689064 chr4:7055603 A/G cg06697600 chr4:7070879 GRPEL1 0.63 9.63 0.46 1.38e-19 Monocyte percentage of white cells; LIHC cis rs7940866 0.903 rs10750457 chr11:130850277 T/C cg12179176 chr11:130786555 SNX19 0.51 7.37 0.37 1.3e-12 Schizophrenia; LIHC cis rs679087 0.606 rs302344 chr12:29940953 A/G cg14258853 chr12:29935411 TMTC1 0.44 6.52 0.33 2.46e-10 Schizophrenia; LIHC cis rs7587476 0.906 rs2734674 chr2:215658895 A/G cg04530015 chr2:215796436 ABCA12 0.41 6.47 0.33 3.34e-10 Neuroblastoma; LIHC cis rs9581857 0.556 rs9581864 chr13:28041567 T/C cg22138327 chr13:27999177 GTF3A 0.45 6.61 0.34 1.45e-10 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC cis rs250677 0.617 rs166106 chr5:148447061 T/C cg18129178 chr5:148520854 ABLIM3 -0.53 -6.85 -0.35 3.36e-11 Breast cancer; LIHC cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg06634786 chr22:41940651 POLR3H 0.8 9.2 0.45 3.64e-18 Vitiligo; LIHC cis rs72781680 0.752 rs72796138 chr2:23926233 C/T cg08917208 chr2:24149416 ATAD2B 0.98 8.29 0.41 2.61e-15 Lymphocyte counts; LIHC cis rs507080 0.961 rs543413 chr11:118550017 T/C cg04173919 chr11:118528438 PHLDB1 0.31 5.88 0.3 9.54e-9 Serum metabolite levels; LIHC cis rs7769051 1.000 rs9493454 chr6:133144629 G/T cg07930552 chr6:133119739 C6orf192 -0.56 -5.85 -0.3 1.18e-8 Type 2 diabetes nephropathy; LIHC cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.73 10.65 0.5 4.5e-23 Lymphocyte counts; LIHC cis rs10193935 0.901 rs62142599 chr2:42548935 G/A cg27598129 chr2:42591480 NA -0.73 -11.37 -0.52 1.24e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs739401 0.572 rs7111857 chr11:3068106 A/G cg08508325 chr11:3079039 CARS 0.37 7.79 0.39 8.06e-14 Longevity; LIHC cis rs17739167 0.569 rs6493015 chr15:42225260 G/T cg20935245 chr15:42234343 EHD4 0.4 7.29 0.37 2.15e-12 Monocyte count; LIHC trans rs1814175 0.935 rs6485999 chr11:49658986 G/C cg03929089 chr4:120376271 NA -0.89 -17.53 -0.69 1.56e-49 Height; LIHC cis rs611744 0.967 rs660816 chr8:109178048 C/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs9394841 0.667 rs9394831 chr6:41753084 C/T cg08135965 chr6:41755394 TOMM6 0.44 5.72 0.3 2.34e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg19318889 chr4:1322082 MAEA 0.4 6.62 0.34 1.37e-10 Obesity-related traits; LIHC cis rs3741151 1.000 rs76570090 chr11:73066321 A/T cg17517138 chr11:73019481 ARHGEF17 0.93 6.79 0.34 4.98e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg06238570 chr21:40685208 BRWD1 0.47 7.54 0.38 4.27e-13 Cognitive function; LIHC cis rs9457247 1.000 rs393727 chr6:167398632 T/A cg23791538 chr6:167370224 RNASET2 -0.65 -11.25 -0.52 3.37e-25 Crohn's disease; LIHC trans rs1814175 0.817 rs10769613 chr11:49769692 G/A cg18944383 chr4:111397179 ENPEP 0.27 7.0 0.35 1.37e-11 Height; LIHC cis rs6840360 0.615 rs7695412 chr4:152488075 A/G cg22705602 chr4:152727874 NA -0.32 -6.37 -0.33 6.2e-10 Intelligence (multi-trait analysis); LIHC cis rs4853012 0.838 rs72915068 chr2:74356185 G/A cg20891558 chr2:74357851 NA 0.82 17.41 0.69 4.68e-49 Gestational age at birth (maternal effect); LIHC cis rs7116495 1.000 rs7948821 chr11:71652485 G/A cg26138937 chr11:71823887 C11orf51 -0.81 -7.95 -0.39 2.76e-14 Severe influenza A (H1N1) infection; LIHC cis rs77106637 0.929 rs1059000 chr11:72504972 G/C cg03713592 chr11:72463424 ARAP1 0.93 8.51 0.42 5.35e-16 Type 2 diabetes; LIHC cis rs2242116 0.727 rs4683298 chr3:46966387 C/G cg27129171 chr3:47204927 SETD2 0.51 8.19 0.4 5.23e-15 Birth weight; LIHC trans rs4906332 0.966 rs12588705 chr14:103865477 T/A cg17675199 chr6:35436792 RPL10A 0.32 6.36 0.33 6.34e-10 Coronary artery disease; LIHC cis rs35306767 0.855 rs61830900 chr10:871481 C/G cg10556349 chr10:835070 NA 0.67 5.85 0.3 1.13e-8 Eosinophil percentage of granulocytes; LIHC cis rs916888 0.773 rs199534 chr17:44824213 T/G cg01570182 chr17:44337453 NA 1.0 9.93 0.47 1.41e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg08643618 chr1:1189466 UBE2J2 0.42 6.1 0.31 2.95e-9 Alopecia areata; LIHC cis rs9814567 0.963 rs9844537 chr3:134238341 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs35110281 0.782 rs9981790 chr21:45045052 G/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.45 6.3 0.32 9.01e-10 Mean corpuscular volume; LIHC cis rs9326248 1.000 rs9326248 chr11:116999225 A/C cg15534755 chr11:117069859 TAGLN 0.36 6.06 0.31 3.68e-9 Blood protein levels; LIHC cis rs9916302 0.706 rs4488484 chr17:37717377 A/T cg07936489 chr17:37558343 FBXL20 0.8 11.29 0.52 2.45e-25 Glomerular filtration rate (creatinine); LIHC cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg20011983 chr2:74347215 NA -0.39 -5.73 -0.3 2.15e-8 Gestational age at birth (maternal effect); LIHC cis rs700651 0.789 rs2196176 chr2:198904914 A/G cg10820045 chr2:198174542 NA 0.44 6.47 0.33 3.38e-10 Intracranial aneurysm; LIHC cis rs11122272 0.735 rs2749705 chr1:231526696 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.25 -0.48 1.1e-21 Hemoglobin concentration; LIHC cis rs7771547 0.573 rs629297 chr6:36398146 C/T cg07856975 chr6:36356162 ETV7 0.35 5.72 0.3 2.32e-8 Platelet distribution width; LIHC cis rs7107174 1.000 rs10793311 chr11:78104399 G/C cg02023728 chr11:77925099 USP35 0.46 8.45 0.42 8.7e-16 Testicular germ cell tumor; LIHC cis rs875971 0.545 rs1638724 chr7:66040481 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.79 -0.34 4.93e-11 Aortic root size; LIHC cis rs11758351 0.866 rs2069019 chr6:26205604 C/T cg23601095 chr6:26197514 HIST1H3D 0.55 5.83 0.3 1.27e-8 Gout;Renal underexcretion gout; LIHC trans rs208515 0.525 rs12204452 chr6:66680325 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.79 0.43 7.58e-17 Exhaled nitric oxide levels; LIHC cis rs7927592 0.956 rs11228278 chr11:68308530 G/A cg16797656 chr11:68205561 LRP5 0.53 8.67 0.42 1.73e-16 Total body bone mineral density; LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.65 -11.26 -0.52 3.13e-25 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg05590025 chr7:65112418 INTS4L2 -0.63 -7.05 -0.36 9.75e-12 Diabetic kidney disease; LIHC trans rs561341 0.700 rs2074101 chr17:30228656 G/A cg20587970 chr11:113659929 NA -0.51 -6.49 -0.33 3.06e-10 Hip circumference adjusted for BMI; LIHC cis rs7772486 0.790 rs9403750 chr6:146167762 G/A cg23711669 chr6:146136114 FBXO30 0.64 11.55 0.53 2.85e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs4727027 0.704 rs10952805 chr7:148907849 G/A cg23583168 chr7:148888333 NA -0.69 -10.84 -0.51 9.78e-24 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2228479 0.541 rs12918575 chr16:89811151 A/G cg04013166 chr16:89971882 TCF25 0.48 6.06 0.31 3.64e-9 Skin colour saturation; LIHC cis rs6582630 0.519 rs11182457 chr12:38538331 G/A cg26384229 chr12:38710491 ALG10B 0.96 12.56 0.56 5.02e-30 Drug-induced liver injury (flucloxacillin); LIHC trans rs800082 0.671 rs800099 chr3:144398547 A/T cg24215973 chr2:240111563 HDAC4 -0.62 -9.17 -0.44 4.37e-18 Smoking behavior; LIHC cis rs3806843 1.000 rs10037757 chr5:140197222 G/T cg26395211 chr5:140044315 WDR55 -0.42 -6.19 -0.32 1.76e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs11167764 0.895 rs6882824 chr5:141474300 A/G cg23435118 chr5:141488016 NDFIP1 -0.43 -5.74 -0.3 2.06e-8 Crohn's disease; LIHC cis rs950169 0.840 rs62029595 chr15:84955301 C/T cg03959625 chr15:84868606 LOC388152 0.48 6.73 0.34 7.19e-11 Schizophrenia; LIHC cis rs11724804 0.532 rs73207782 chr4:848764 G/C cg23939001 chr4:940644 TMEM175 0.49 6.42 0.33 4.55e-10 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs7551222 0.752 rs2369244 chr1:204515299 C/G cg20240347 chr1:204465584 NA 0.33 6.99 0.35 1.42e-11 Schizophrenia; LIHC cis rs727505 1.000 rs7790856 chr7:124459852 C/T cg23710748 chr7:124431027 NA -0.33 -5.81 -0.3 1.4e-8 Lewy body disease; LIHC cis rs6024905 0.587 rs2154374 chr20:36963225 A/G cg07053727 chr20:36965646 BPI 0.57 10.37 0.49 4.21e-22 Bipolar disorder and schizophrenia; LIHC cis rs7072216 0.727 rs7913541 chr10:100172479 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.35 -0.32 6.94e-10 Metabolite levels; LIHC cis rs2073499 1.000 rs2071802 chr3:50412945 A/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.65 6.58 0.34 1.8e-10 Schizophrenia; LIHC cis rs12464483 0.524 rs2256411 chr2:30886860 C/A cg17749961 chr2:30669863 LCLAT1 0.52 6.55 0.33 2.08e-10 Pre-treatment pain in head and neck squamous cell carcinoma; LIHC cis rs7845219 0.539 rs713113 chr8:95877787 C/T cg09323728 chr8:95962352 TP53INP1 0.28 5.79 0.3 1.56e-8 Type 2 diabetes; LIHC cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.66e-9 Bipolar disorder; LIHC cis rs10214930 0.560 rs42089 chr7:27702940 C/T cg05786569 chr7:27702416 HIBADH -0.61 -9.36 -0.45 1.12e-18 Hypospadias; LIHC cis rs2204008 0.715 rs12815986 chr12:38343869 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.56 0.5 9.14e-23 Bladder cancer; LIHC cis rs9309473 0.687 rs11126399 chr2:73613341 G/A cg20560298 chr2:73613845 ALMS1 -0.44 -6.75 -0.34 6.25e-11 Metabolite levels; LIHC cis rs9303401 0.659 rs7224276 chr17:56897827 C/T cg25039879 chr17:56429692 SUPT4H1 0.77 8.91 0.43 3e-17 Cognitive test performance; LIHC cis rs58688157 0.705 rs36060383 chr11:598723 A/C cg16486109 chr11:613632 IRF7 0.58 6.25 0.32 1.21e-9 Systemic lupus erythematosus; LIHC cis rs1538970 0.884 rs781226 chr1:45872662 T/C cg15605315 chr1:45957053 TESK2 0.43 5.83 0.3 1.25e-8 Platelet count; LIHC cis rs11650494 0.710 rs8066722 chr17:47475007 A/G cg08112188 chr17:47440006 ZNF652 -0.8 -5.92 -0.3 7.88e-9 Prostate cancer; LIHC cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg05590025 chr7:65112418 INTS4L2 -0.62 -6.79 -0.34 4.9e-11 Diabetic kidney disease; LIHC cis rs16854884 0.586 rs7639366 chr3:143752034 T/G cg06585982 chr3:143692056 C3orf58 0.58 7.56 0.38 3.77e-13 Economic and political preferences (feminism/equality); LIHC cis rs12824058 0.831 rs7485200 chr12:130811641 C/T cg24838063 chr12:130822603 PIWIL1 0.67 9.91 0.47 1.62e-20 Menopause (age at onset); LIHC cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg13395646 chr4:1353034 KIAA1530 -0.45 -6.7 -0.34 8.66e-11 Longevity; LIHC cis rs7116495 0.609 rs628025 chr11:71802351 A/C cg10381502 chr11:71823885 C11orf51 -1.07 -8.58 -0.42 3.29e-16 Severe influenza A (H1N1) infection; LIHC cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg08822215 chr16:89438651 ANKRD11 -0.47 -7.33 -0.37 1.73e-12 Multiple myeloma (IgH translocation); LIHC cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg00149659 chr3:10157352 C3orf10 0.68 7.16 0.36 4.9e-12 Alzheimer's disease; LIHC cis rs10791097 0.678 rs10894272 chr11:130731081 A/G cg09137382 chr11:130731461 NA 0.42 6.62 0.34 1.37e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs9399135 0.933 rs7755680 chr6:135294259 A/G cg22676075 chr6:135203613 NA 0.4 6.45 0.33 3.85e-10 Red blood cell count; LIHC cis rs600806 0.778 rs4970766 chr1:110013955 A/G cg02415029 chr1:110025642 ATXN7L2 0.45 5.86 0.3 1.08e-8 Intelligence (multi-trait analysis); LIHC cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.17 -0.32 1.88e-9 Calcium levels; LIHC cis rs2084898 0.550 rs470411 chr11:120012390 G/C cg03452187 chr11:120039793 NA -0.42 -6.25 -0.32 1.24e-9 Stroke (pediatric); LIHC cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg07061783 chr6:25882402 NA -0.48 -5.84 -0.3 1.2e-8 Intelligence (multi-trait analysis); LIHC cis rs4332037 0.722 rs4719332 chr7:1914681 G/A cg23043544 chr7:2124092 MAD1L1 -0.42 -6.3 -0.32 9.06e-10 Bipolar disorder; LIHC cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.49e-11 Diabetic kidney disease; LIHC cis rs7647973 0.577 rs6446247 chr3:49102001 A/T cg07636037 chr3:49044803 WDR6 0.76 9.06 0.44 1.03e-17 Menarche (age at onset); LIHC cis rs5758659 0.714 rs6002626 chr22:42517989 C/G cg19513890 chr22:42538836 CYP2D7P1 0.43 8.33 0.41 1.94e-15 Cognitive function; LIHC cis rs8013055 0.706 rs8003957 chr14:105971702 A/G cg19700328 chr14:106028568 NA -0.35 -7.48 -0.37 6.44e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); LIHC cis rs1577917 0.917 rs2197651 chr6:86495442 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.31 -0.49 7.17e-22 Response to antipsychotic treatment; LIHC cis rs311392 1.000 rs2666870 chr8:55086427 T/C cg20636351 chr8:55087400 NA -0.33 -6.65 -0.34 1.13e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs2073300 0.609 rs3746733 chr20:23349749 C/T cg12062639 chr20:23401060 NAPB 1.05 14.03 0.6 1.22e-35 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2842992 0.789 rs2146163 chr6:160224346 T/C cg11366901 chr6:160182831 ACAT2 0.93 15.15 0.63 5.07e-40 Age-related macular degeneration (geographic atrophy); LIHC cis rs67311347 0.866 rs9826419 chr3:40352051 G/A cg00656387 chr3:40428638 ENTPD3 0.39 6.03 0.31 4.26e-9 Renal cell carcinoma; LIHC cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.15e-11 Prudent dietary pattern; LIHC cis rs9457247 0.602 rs2157388 chr6:167481912 G/A cg23791538 chr6:167370224 RNASET2 -0.53 -7.87 -0.39 4.67e-14 Crohn's disease; LIHC cis rs10411936 0.682 rs6512113 chr19:16598269 C/T cg10248733 chr19:16607483 C19orf44;CALR3 0.52 6.9 0.35 2.53e-11 White blood cell count;Multiple sclerosis; LIHC cis rs986417 0.901 rs6573314 chr14:60972045 C/T cg27398547 chr14:60952738 C14orf39 0.78 8.57 0.42 3.61e-16 Gut microbiota (bacterial taxa); LIHC cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg21644426 chr2:191273491 MFSD6 0.55 7.72 0.39 1.3e-13 Pulse pressure; LIHC cis rs10857712 0.754 rs2297031 chr10:135232654 C/T cg19623624 chr10:135278901 LOC619207 -0.44 -6.81 -0.35 4.46e-11 Systemic lupus erythematosus; LIHC cis rs11663156 1.000 rs66920460 chr18:50917496 C/A cg24270629 chr18:50823537 DCC -0.5 -6.78 -0.34 5.21e-11 Intelligence (multi-trait analysis); LIHC cis rs7715806 0.500 rs2307112 chr5:75003413 A/C cg00601450 chr5:74908170 NA 0.52 6.48 0.33 3.27e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg05368731 chr17:41323189 NBR1 0.73 12.45 0.56 1.39e-29 Menopause (age at onset); LIHC cis rs9611565 0.592 rs5751129 chr22:42015765 C/T cg03806693 chr22:41940476 POLR3H 0.8 9.18 0.44 4.33e-18 Vitiligo; LIHC cis rs35955747 0.838 rs28716 chr22:31730189 A/C cg22777020 chr22:31556080 RNF185 0.49 5.72 0.3 2.3e-8 Neutrophil count;Sum basophil neutrophil counts; LIHC trans rs2727020 0.521 rs11039902 chr11:48679467 A/G cg15704280 chr7:45808275 SEPT13 -0.5 -7.63 -0.38 2.28e-13 Coronary artery disease; LIHC cis rs6840360 0.571 rs7678080 chr4:152557350 A/G cg22705602 chr4:152727874 NA -0.31 -6.16 -0.32 1.99e-9 Intelligence (multi-trait analysis); LIHC cis rs3018712 0.532 rs57813595 chr11:68402606 C/G cg20283391 chr11:68216788 NA -0.5 -5.99 -0.31 5.23e-9 Total body bone mineral density; LIHC cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg11644478 chr21:40555479 PSMG1 -0.42 -6.59 -0.34 1.63e-10 Cognitive function; LIHC cis rs66887589 0.720 rs11724758 chr4:120239878 G/A cg09307838 chr4:120376055 NA 0.53 7.99 0.4 2.05e-14 Diastolic blood pressure; LIHC cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.06e-10 Alzheimer's disease; LIHC cis rs11212260 0.655 rs11212246 chr11:107320778 T/C cg25435332 chr11:107328525 CWF19L2 0.83 8.36 0.41 1.55e-15 IgG glycosylation; LIHC cis rs950169 0.881 rs72750843 chr15:85135783 C/T cg17507749 chr15:85114479 UBE2QP1 0.74 8.04 0.4 1.47e-14 Schizophrenia; LIHC cis rs7772486 0.720 rs6570713 chr6:146075085 G/A cg05347473 chr6:146136440 FBXO30 -0.37 -5.99 -0.31 5.46e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.830 rs7209321 chr17:61855668 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.13 0.79 7.7e-76 Prudent dietary pattern; LIHC cis rs3204270 0.639 rs11871678 chr17:79654285 G/A cg18367735 chr17:79674897 NA 0.7 8.23 0.41 4.05e-15 Dental caries; LIHC cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs6964587 1.000 rs10264666 chr7:91578639 G/A cg17063962 chr7:91808500 NA -1.03 -19.89 -0.73 4.87e-59 Breast cancer; LIHC cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg20090690 chr10:134436459 INPP5A 0.45 5.74 0.3 2.04e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs17102423 0.755 rs11625045 chr14:65549089 C/T cg11161011 chr14:65562177 MAX -0.53 -7.57 -0.38 3.41e-13 Obesity-related traits; LIHC cis rs1670533 0.872 rs10017931 chr4:1060747 G/A cg27284194 chr4:1044797 NA 0.58 8.73 0.43 1.16e-16 Recombination rate (females); LIHC cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg11062466 chr8:58055876 NA 0.51 7.09 0.36 7.72e-12 Developmental language disorder (linguistic errors); LIHC cis rs1023500 0.505 rs134901 chr22:42683520 C/T cg04733989 chr22:42467013 NAGA 0.45 6.65 0.34 1.14e-10 Schizophrenia; LIHC cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg18306943 chr3:40428807 ENTPD3 0.34 5.86 0.3 1.1e-8 Renal cell carcinoma; LIHC cis rs2439831 0.867 rs2447196 chr15:43893818 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.57 -7.14 -0.36 5.65e-12 Lung cancer in ever smokers; LIHC cis rs3099143 1.000 rs3106378 chr15:77110524 A/C cg21673338 chr15:77095150 SCAPER -0.51 -7.64 -0.38 2.21e-13 Recalcitrant atopic dermatitis; LIHC trans rs61931739 0.534 rs4001713 chr12:34154195 A/C cg26384229 chr12:38710491 ALG10B -0.55 -7.18 -0.36 4.42e-12 Morning vs. evening chronotype; LIHC cis rs483180 0.512 rs677277 chr1:120202298 C/T cg19096424 chr1:120255104 PHGDH -0.59 -7.44 -0.37 8.13e-13 Macular telangiectasia type 2; LIHC cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.86 0.3 1.12e-8 Menopause (age at onset); LIHC cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg27211696 chr2:191398769 TMEM194B 0.64 10.6 0.5 6.71e-23 Pulse pressure; LIHC cis rs796364 0.806 rs74706215 chr2:200941367 T/C cg12253985 chr2:200820533 C2orf60;C2orf47 -0.76 -8.51 -0.42 5.73e-16 Schizophrenia; LIHC cis rs8017423 0.765 rs8017170 chr14:90721849 T/A cg04374321 chr14:90722782 PSMC1 0.77 15.19 0.63 3.32e-40 Mortality in heart failure; LIHC cis rs7618501 0.933 rs6809431 chr3:49804119 A/G cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.34e-11 Intelligence (multi-trait analysis); LIHC cis rs2257205 0.667 rs6503872 chr17:56696008 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs807669 0.524 rs11089258 chr22:19162276 C/T cg02655711 chr22:19163373 SLC25A1 0.36 6.47 0.33 3.35e-10 Metabolite levels; LIHC cis rs7727544 0.735 rs272842 chr5:131656517 A/G cg24060327 chr5:131705240 SLC22A5 -0.56 -8.07 -0.4 1.19e-14 Blood metabolite levels; LIHC cis rs11671005 0.693 rs11669665 chr19:58931885 G/A cg25952890 chr19:58913133 NA 0.67 7.2 0.36 3.89e-12 Mean platelet volume; LIHC cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.97 -0.31 6.04e-9 Colorectal cancer; LIHC cis rs17685 0.712 rs11770149 chr7:75791644 G/A cg16684958 chr7:75615977 POR 0.39 6.29 0.32 9.58e-10 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg25554917 chr2:170220129 LRP2 0.41 6.18 0.32 1.85e-9 Alopecia areata; LIHC cis rs739401 0.611 rs572373 chr11:3055361 T/C cg25174290 chr11:3078921 CARS 0.6 8.97 0.44 2.02e-17 Longevity; LIHC cis rs1005277 0.505 rs7099777 chr10:38183569 A/C cg00409905 chr10:38381863 ZNF37A 0.55 9.56 0.46 2.37e-19 Extrinsic epigenetic age acceleration; LIHC cis rs7523273 1.000 rs34385765 chr1:207993637 A/G cg22525895 chr1:207977042 MIR29B2 -0.69 -10.45 -0.49 2.26e-22 Schizophrenia; LIHC cis rs11864453 1.000 rs2278027 chr16:72051369 A/G cg01557791 chr16:72042693 DHODH -0.72 -11.8 -0.54 3.35e-27 Fibrinogen levels; LIHC cis rs11105298 0.891 rs3741898 chr12:89933763 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.53 -0.38 4.6e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs4969178 0.965 rs938350 chr17:76399552 C/T cg20026190 chr17:76395443 PGS1 0.44 7.04 0.36 1.09e-11 HDL cholesterol levels; LIHC cis rs8062405 1.000 rs61737565 chr16:28855522 G/C cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7927592 0.731 rs2156463 chr11:68386311 T/C cg20283391 chr11:68216788 NA -0.38 -5.91 -0.3 8.16e-9 Total body bone mineral density; LIHC cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9611565 0.568 rs5751159 chr22:42175365 G/A cg03806693 chr22:41940476 POLR3H 0.79 8.66 0.42 1.89e-16 Vitiligo; LIHC trans rs4927850 1.000 rs10881564 chr3:195750326 C/T cg16724585 chr3:197361211 NA -0.46 -6.44 -0.33 4.11e-10 Pancreatic cancer; LIHC cis rs4934494 0.727 rs67827533 chr10:91505383 C/T cg19698084 chr10:91461284 KIF20B -0.47 -6.28 -0.32 1.02e-9 Red blood cell count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03771185 chr4:775700 NA 0.4 6.45 0.33 3.82e-10 Cognitive function; LIHC cis rs9596863 0.898 rs9568906 chr13:54335197 A/G ch.13.53330881F chr13:54432880 NA 0.45 6.18 0.32 1.78e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg04781839 chr16:1374937 UBE2I 0.51 6.98 0.35 1.58e-11 Hepatitis; LIHC cis rs11603020 0.950 rs28362950 chr11:57371918 G/A cg19752551 chr11:57585705 CTNND1 -0.47 -5.99 -0.31 5.22e-9 Blood protein levels; LIHC cis rs8078723 0.510 rs3859189 chr17:38137033 A/G cg17467752 chr17:38218738 THRA -0.56 -9.55 -0.46 2.56e-19 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2549003 1.000 rs2549002 chr5:131829578 C/A cg02551604 chr5:131831745 NA 0.45 6.86 0.35 3.28e-11 Asthma (sex interaction); LIHC cis rs1801251 1.000 rs11679079 chr2:233612656 C/T cg08000102 chr2:233561755 GIGYF2 0.76 11.47 0.53 5.31e-26 Coronary artery disease; LIHC cis rs75908454 1.000 rs77983924 chr6:169993627 T/C cg19338460 chr6:170058176 WDR27 -0.92 -8.86 -0.43 4.39e-17 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs599083 0.530 rs2508834 chr11:68175354 C/T cg16797656 chr11:68205561 LRP5 -0.49 -7.64 -0.38 2.16e-13 Bone mineral density (spine); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02793854 chr16:67867809 CENPT -0.5 -6.31 -0.32 8.89e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs807029 0.533 rs3740485 chr10:102750621 C/T cg25179470 chr10:102756915 LZTS2 0.45 6.32 0.32 8.06e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg14004847 chr7:1930337 MAD1L1 -0.47 -6.9 -0.35 2.49e-11 Bipolar disorder and schizophrenia; LIHC cis rs3806843 0.966 rs3756341 chr5:140171194 C/T cg19875535 chr5:140030758 IK 0.36 5.9 0.3 8.8e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4453791 0.656 rs62242262 chr3:38937383 C/A cg02254461 chr3:39195904 CSRNP1 0.64 5.72 0.3 2.38e-8 Social communication problems; LIHC cis rs2274273 1.000 rs2147972 chr14:55598030 T/C cg01864836 chr14:55583639 NA -0.36 -6.15 -0.32 2.14e-9 Protein biomarker; LIHC cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg07424592 chr7:64974309 NA 0.82 9.53 0.46 2.98e-19 Diabetic kidney disease; LIHC cis rs60871478 0.635 rs4311567 chr7:792295 T/C cg05535760 chr7:792225 HEATR2 0.97 13.24 0.58 1.36e-32 Cerebrospinal P-tau181p levels; LIHC cis rs7818688 0.614 rs73271148 chr8:95876545 C/T cg16049864 chr8:95962084 TP53INP1 0.51 5.85 0.3 1.18e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs2836974 0.644 rs2836982 chr21:40689171 C/A cg17971929 chr21:40555470 PSMG1 -0.45 -6.87 -0.35 3.09e-11 Cognitive function; LIHC cis rs10791097 0.653 rs11222362 chr11:130731425 T/C cg14779329 chr11:130786720 SNX19 0.38 5.88 0.3 9.95e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs12477438 0.765 rs2309520 chr2:99570477 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.7 10.21 0.48 1.55e-21 Chronic sinus infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08187083 chr17:30186506 C17orf79 -0.44 -6.08 -0.31 3.21e-9 Pancreatic cancer; LIHC cis rs79149102 0.579 rs61166993 chr15:75306644 C/A cg09165964 chr15:75287851 SCAMP5 -0.57 -7.9 -0.39 3.94e-14 Lung cancer; LIHC cis rs9640161 0.830 rs3735165 chr7:150068371 T/C cg10018233 chr7:150070692 REPIN1 0.72 13.63 0.59 4.28e-34 Blood protein levels;Circulating chemerin levels; LIHC cis rs2066819 1.000 rs111885088 chr12:56657216 A/C cg26734620 chr12:56694298 CS 1.28 10.93 0.51 4.65e-24 Psoriasis vulgaris; LIHC cis rs7395581 0.959 rs326222 chr11:47259668 A/G cg26139080 chr11:47293733 MADD 0.47 7.98 0.4 2.18e-14 HDL cholesterol; LIHC cis rs735396 0.770 rs1169300 chr12:121431225 G/A cg02403541 chr12:121454288 C12orf43 0.51 8.89 0.43 3.66e-17 N-glycan levels; LIHC cis rs35110281 0.776 rs2838316 chr21:44990036 C/T cg21573476 chr21:45109991 RRP1B -0.58 -11.15 -0.52 8.02e-25 Mean corpuscular volume; LIHC trans rs800082 0.539 rs1178897 chr3:144241161 A/C cg24215973 chr2:240111563 HDAC4 -0.49 -6.74 -0.34 6.91e-11 Smoking behavior; LIHC cis rs2629540 0.586 rs10794183 chr10:126536609 G/C cg08799069 chr10:126477246 METTL10 -0.43 -6.69 -0.34 9.1e-11 Cocaine dependence; LIHC cis rs7089973 0.604 rs7915943 chr10:116618077 G/A cg03647239 chr10:116582469 FAM160B1 0.46 6.71 0.34 8.34e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs10883723 0.773 rs2296587 chr10:104245588 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 8.94 0.44 2.43e-17 Allergic disease (asthma, hay fever or eczema); LIHC cis rs61990749 0.544 rs8003979 chr14:78211290 C/T cg21497246 chr14:78225524 SNW1;C14orf178 -0.51 -7.75 -0.39 1.02e-13 Fibroblast growth factor basic levels; LIHC cis rs921968 0.544 rs58827325 chr2:219415166 A/T cg02985541 chr2:219472218 PLCD4 0.41 6.77 0.34 5.48e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7727544 0.684 rs270602 chr5:131656700 T/C cg07395648 chr5:131743802 NA -0.31 -6.32 -0.32 8.05e-10 Blood metabolite levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg02322435 chr11:67815326 TCIRG1 0.43 6.4 0.33 5.2e-10 Bilirubin levels; LIHC cis rs2762353 0.603 rs4145221 chr6:25763192 A/G cg03517284 chr6:25882590 NA 0.48 6.49 0.33 2.98e-10 Blood metabolite levels; LIHC cis rs4638749 0.677 rs2219081 chr2:108844350 T/C cg25838818 chr2:108905173 SULT1C2 -0.4 -7.03 -0.36 1.15e-11 Blood pressure; LIHC cis rs2933343 0.700 rs2249514 chr3:128643812 C/T cg24203234 chr3:128598194 ACAD9 0.46 6.47 0.33 3.43e-10 IgG glycosylation; LIHC cis rs4746818 1.000 rs906217 chr10:70954661 T/C cg11621586 chr10:70884670 VPS26A 0.81 11.41 0.53 9.05e-26 Left atrial antero-posterior diameter; LIHC cis rs6785206 0.803 rs6774512 chr3:128415868 C/T cg16766828 chr3:128327626 NA -0.61 -6.73 -0.34 7.23e-11 Lymphocyte percentage of white cells; LIHC cis rs7618501 1.000 rs9859153 chr3:49807085 G/T cg24110177 chr3:50126178 RBM5 -0.43 -6.69 -0.34 9.34e-11 Intelligence (multi-trait analysis); LIHC cis rs11098699 0.821 rs2047201 chr4:124233384 A/G cg09941581 chr4:124220074 SPATA5 -0.3 -5.84 -0.3 1.18e-8 Mosquito bite size; LIHC cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg05368731 chr17:41323189 NBR1 0.72 12.47 0.56 1.08e-29 Menopause (age at onset); LIHC cis rs5769707 0.967 rs9616327 chr22:50010891 G/A cg01652190 chr22:50026171 C22orf34 -0.3 -7.08 -0.36 8.08e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs11958404 0.932 rs72816556 chr5:157424412 C/G cg05962755 chr5:157440814 NA 0.9 10.15 0.48 2.55e-21 IgG glycosylation; LIHC cis rs7903847 0.642 rs11189182 chr10:99144186 A/G cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs2115536 0.967 rs4778734 chr15:80210851 A/G cg00225070 chr15:80189496 MTHFS 0.53 8.65 0.42 2.04e-16 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; LIHC cis rs780096 0.565 rs13022659 chr2:27743630 C/T cg05484376 chr2:27715224 FNDC4 0.4 6.57 0.33 1.85e-10 Total body bone mineral density; LIHC cis rs8062405 0.755 rs4787455 chr16:28589455 G/A cg00204512 chr16:28754710 NA 0.4 6.82 0.35 4.26e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08269949 chr6:26538502 HMGN4 0.53 7.37 0.37 1.28e-12 Pancreatic cancer; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.21 -0.32 1.5e-9 Total body bone mineral density; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13294780 chr4:140005756 ELF2 0.47 6.69 0.34 9.06e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg22903471 chr2:27725779 GCKR -0.5 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.51 8.91 0.43 3.11e-17 Electroencephalogram traits; LIHC cis rs7659604 0.967 rs28529384 chr4:122664215 T/C cg19748678 chr4:122722346 EXOSC9 0.37 6.33 0.32 7.72e-10 Type 2 diabetes; LIHC cis rs7918232 0.941 rs7907988 chr10:27444344 T/G cg14240646 chr10:27532245 ACBD5 -0.65 -6.21 -0.32 1.57e-9 Breast cancer; LIHC cis rs7412746 0.658 rs4970982 chr1:150865084 G/C cg18016565 chr1:150552671 MCL1 0.51 9.75 0.47 5.67e-20 Melanoma; LIHC cis rs8062405 0.964 rs9972768 chr16:28861734 A/C cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs2726453 0.562 rs2713834 chr4:106310520 G/T cg11199428 chr13:52027379 INTS6 -0.47 -6.24 -0.32 1.27e-9 Intelligence (multi-trait analysis); LIHC cis rs5769765 0.874 rs11703411 chr22:50258751 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.7 9.11 0.44 6.88e-18 Schizophrenia; LIHC cis rs10791097 0.667 rs12363163 chr11:130744509 A/G cg12179176 chr11:130786555 SNX19 0.81 13.1 0.58 4.89e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs2018683 0.745 rs917217 chr7:28975025 G/T cg19402173 chr7:128379420 CALU 0.39 6.28 0.32 1.05e-9 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs727505 1.000 rs10228201 chr7:124449895 A/G cg23710748 chr7:124431027 NA -0.33 -5.73 -0.3 2.25e-8 Lewy body disease; LIHC cis rs708547 0.836 rs1315005 chr4:57858237 C/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.63 9.02 0.44 1.37e-17 Response to bleomycin (chromatid breaks); LIHC cis rs11997175 0.511 rs4613957 chr8:33673130 C/T ch.8.33884649F chr8:33765107 NA -0.31 -5.87 -0.3 1.01e-8 Body mass index; LIHC cis rs875971 0.964 rs2277911 chr7:65958625 T/G cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs10876993 0.728 rs1082503 chr12:58036717 G/A cg15848620 chr12:58087721 OS9 -0.55 -7.52 -0.38 4.99e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs597539 0.652 rs673821 chr11:68678718 G/T cg04772025 chr11:68637568 NA 0.49 6.34 0.32 7.25e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs17854409 0.764 rs8114722 chr20:61478492 G/A cg05147244 chr20:61493195 TCFL5 1.28 10.63 0.5 5.23e-23 Obesity-related traits; LIHC cis rs6964587 0.773 rs13236026 chr7:91885873 A/G cg17063962 chr7:91808500 NA 0.97 16.83 0.67 9.63e-47 Breast cancer; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg10150615 chr22:24372951 LOC391322 -0.56 -8.44 -0.42 9.07e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs4808199 0.948 rs7250368 chr19:19452763 G/A cg03709012 chr19:19516395 GATAD2A 0.99 15.8 0.65 1.29e-42 Nonalcoholic fatty liver disease; LIHC cis rs2749592 0.550 rs4934881 chr10:37914346 A/C cg00409905 chr10:38381863 ZNF37A 0.52 8.65 0.42 2.09e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2067615 0.560 rs1882542 chr12:107070049 A/C cg15890332 chr12:107067104 RFX4 0.27 6.42 0.33 4.64e-10 Heart rate; LIHC cis rs11112613 0.762 rs73184078 chr12:105950017 A/G cg03607813 chr12:105948248 NA 0.67 13.37 0.59 4.49e-33 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7959452 0.868 rs10878967 chr12:69740869 T/C cg20891283 chr12:69753455 YEATS4 0.7 11.99 0.54 6.64e-28 Blood protein levels; LIHC cis rs2242116 0.796 rs4683297 chr3:46973673 T/C cg27129171 chr3:47204927 SETD2 -0.56 -9.03 -0.44 1.28e-17 Birth weight; LIHC cis rs7258465 1.000 rs10442 chr19:18545341 A/C cg10790698 chr19:18539756 SSBP4 -0.36 -7.29 -0.37 2.13e-12 Breast cancer; LIHC cis rs10779751 0.770 rs7553827 chr1:11222393 C/T cg08854313 chr1:11322531 MTOR 0.73 9.29 0.45 1.81e-18 Body mass index; LIHC cis rs3806843 0.705 rs2530230 chr5:140088131 G/A cg16577123 chr5:140027231 NDUFA2;IK -0.41 -5.88 -0.3 9.95e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs35110281 0.811 rs2838337 chr21:45072621 A/C cg04455712 chr21:45112962 RRP1B 0.45 7.8 0.39 7.5e-14 Mean corpuscular volume; LIHC cis rs10170846 0.861 rs4674677 chr2:223529658 G/A cg25565276 chr2:223520875 FARSB 0.62 9.19 0.44 4.04e-18 Schizophrenia (inflammation and infection response interaction); LIHC cis rs4919087 0.620 rs793518 chr10:98986970 C/T cg25902810 chr10:99078978 FRAT1 -0.56 -6.29 -0.32 9.75e-10 Monocyte count; LIHC cis rs3806843 1.000 rs991918 chr5:140194858 C/T cg19875535 chr5:140030758 IK 0.36 5.82 0.3 1.37e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs1005277 0.579 rs2472182 chr10:38388865 T/C cg17830980 chr10:43048298 ZNF37B -0.55 -11.26 -0.52 3.18e-25 Extrinsic epigenetic age acceleration; LIHC cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg11502198 chr6:26597334 ABT1 -0.61 -9.6 -0.46 1.81e-19 Intelligence (multi-trait analysis); LIHC cis rs10870270 0.956 rs11146425 chr10:133734261 C/T cg26149184 chr10:133730230 NA 0.46 7.34 0.37 1.56e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs208520 0.690 rs12202401 chr6:66760544 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.8 9.11 0.44 7.24e-18 Exhaled nitric oxide output; LIHC cis rs4819052 0.765 rs2838854 chr21:46680364 A/G cg22633049 chr21:46681294 NA -0.35 -6.1 -0.31 2.89e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs67311347 1.000 rs2305521 chr3:40429183 A/G cg09455208 chr3:40491958 NA 0.34 6.86 0.35 3.24e-11 Renal cell carcinoma; LIHC cis rs2292864 0.764 rs3892085 chr17:45340480 A/G cg18085866 chr17:45331354 ITGB3 -0.64 -7.3 -0.37 2.03e-12 Left atrial antero-posterior diameter; LIHC cis rs9549328 0.800 rs1317507 chr13:113631780 G/T cg08528486 chr13:113648767 MCF2L -0.38 -6.44 -0.33 4.06e-10 Systolic blood pressure; LIHC cis rs7666738 0.800 rs10008654 chr4:98820498 C/A cg05340658 chr4:99064831 C4orf37 0.63 11.49 0.53 4.74e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs4555082 0.834 rs2735822 chr14:105712734 C/T cg10792982 chr14:105748885 BRF1 0.49 6.35 0.32 6.85e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg04025307 chr7:1156635 C7orf50 0.59 10.37 0.49 4.17e-22 Longevity;Endometriosis; LIHC cis rs7520050 0.553 rs2993263 chr1:46021630 A/G cg03146154 chr1:46216737 IPP 0.43 6.87 0.35 2.97e-11 Red blood cell count;Reticulocyte count; LIHC trans rs1499614 1.000 rs2707828 chr7:66171377 G/A cg05590025 chr7:65112418 INTS4L2 -0.56 -6.23 -0.32 1.36e-9 Gout; LIHC cis rs1568889 0.838 rs11030230 chr11:28174631 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 14.27 0.61 1.4e-36 Bipolar disorder; LIHC cis rs734999 0.588 rs6668149 chr1:2558308 A/C cg18854424 chr1:2615690 NA -0.34 -7.36 -0.37 1.38e-12 Ulcerative colitis; LIHC cis rs7584330 0.554 rs114331205 chr2:238432559 A/C cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.42e-9 Prostate cancer; LIHC cis rs1023500 0.507 rs6002600 chr22:42488906 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Schizophrenia; LIHC cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg11987759 chr7:65425863 GUSB -0.39 -6.09 -0.31 3.1e-9 Calcium levels; LIHC trans rs875971 0.545 rs73146609 chr7:65767464 A/G cg26939375 chr7:64535504 NA 0.4 6.37 0.33 6.14e-10 Aortic root size; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg27619136 chr4:174291353 SAP30 0.41 6.28 0.32 1.01e-9 Morning vs. evening chronotype; LIHC trans rs561341 1.000 rs7210970 chr17:30262169 G/A cg20587970 chr11:113659929 NA -0.58 -6.74 -0.34 6.58e-11 Hip circumference adjusted for BMI; LIHC cis rs826838 0.967 rs12823908 chr12:38845686 T/C cg13010199 chr12:38710504 ALG10B 0.61 7.5 0.38 5.64e-13 Heart rate; LIHC cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg24209194 chr3:40518798 ZNF619 0.66 9.78 0.47 4.46e-20 Renal cell carcinoma; LIHC cis rs787274 0.681 rs787270 chr9:115549092 C/T cg13803584 chr9:115635662 SNX30 -0.59 -6.39 -0.33 5.54e-10 Age-related hearing impairment (SNP x SNP interaction); LIHC trans rs875971 1.000 rs4718344 chr7:65874381 C/A cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg20302342 chr1:156215951 PAQR6 0.33 6.29 0.32 9.54e-10 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs12579753 1.000 rs10862371 chr12:82249298 C/T cg07988820 chr12:82153109 PPFIA2 -0.49 -5.98 -0.31 5.64e-9 Resting heart rate; LIHC cis rs1843834 0.505 rs4674911 chr2:225345254 A/G cg22509189 chr2:225307070 NA -0.83 -11.72 -0.54 6.47e-27 IgE levels in asthmatics (D.p. specific); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18803079 chr1:64014643 EFCAB7;DLEU2L 0.44 6.4 0.33 5.02e-10 Pancreatic cancer; LIHC trans rs2727020 0.718 rs1404366 chr11:49415899 T/A cg03929089 chr4:120376271 NA -0.7 -11.01 -0.51 2.49e-24 Coronary artery disease; LIHC cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.87 -11.32 -0.52 1.87e-25 Alzheimer's disease; LIHC cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg08132940 chr7:1081526 C7orf50 -0.79 -6.69 -0.34 9.22e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg11062466 chr8:58055876 NA 0.47 6.41 0.33 4.89e-10 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11695601 chr2:175870435 CHN1 0.43 6.25 0.32 1.19e-9 Pancreatic cancer; LIHC cis rs2404602 0.647 rs11072626 chr15:77090826 A/G cg23625390 chr15:77176239 SCAPER -0.56 -9.42 -0.45 6.76e-19 Blood metabolite levels; LIHC cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.73 0.39 1.18e-13 Electroencephalogram traits; LIHC cis rs3749237 0.615 rs11130202 chr3:49566715 C/T cg07636037 chr3:49044803 WDR6 0.57 8.53 0.42 4.79e-16 Resting heart rate; LIHC cis rs11951515 0.508 rs6898866 chr5:43586375 G/A cg01983248 chr5:43482804 C5orf28 -0.37 -6.06 -0.31 3.64e-9 Metabolite levels (X-11787); LIHC cis rs748404 0.697 rs475261 chr15:43546456 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.5 8.6 0.42 2.91e-16 Lung cancer; LIHC cis rs2732480 0.577 rs2732479 chr12:48736260 A/C cg21466736 chr12:48725269 NA -0.72 -11.03 -0.51 2.11e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs1800469 1.000 rs2241714 chr19:41869392 C/T cg08477640 chr19:41863820 B9D2 -0.35 -5.84 -0.3 1.19e-8 Colorectal cancer; LIHC cis rs10744422 1.000 rs12255 chr12:123350204 C/T cg25930673 chr12:123319894 HIP1R -0.85 -10.56 -0.5 9.18e-23 Schizophrenia; LIHC cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg00656387 chr3:40428638 ENTPD3 -0.42 -7.12 -0.36 6.45e-12 Renal cell carcinoma; LIHC cis rs8114671 0.836 rs17404569 chr20:33674077 A/C cg07148914 chr20:33460835 GGT7 -0.55 -8.3 -0.41 2.48e-15 Height; LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC trans rs1005277 0.579 rs2505237 chr10:38438898 T/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7188697 0.922 rs9924805 chr16:58615659 T/C cg02549819 chr16:58548995 SETD6 0.48 7.62 0.38 2.52e-13 QT interval; LIHC cis rs66887589 0.777 rs2017058 chr4:120257739 T/C cg09307838 chr4:120376055 NA 0.45 6.91 0.35 2.39e-11 Diastolic blood pressure; LIHC cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg24642844 chr7:1081250 C7orf50 -0.72 -7.12 -0.36 6.6e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4713118 0.513 rs149975 chr6:27986340 G/A cg23485639 chr6:28045615 ZNF165 0.38 5.89 0.3 9.04e-9 Parkinson's disease; LIHC cis rs12477438 0.798 rs12477754 chr2:99628073 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.92 -0.65 4.52e-43 Chronic sinus infection; LIHC cis rs11971779 0.941 rs74299967 chr7:139043769 G/T cg07862535 chr7:139043722 LUC7L2 0.69 11.19 0.52 5.54e-25 Diisocyanate-induced asthma; LIHC cis rs11583043 1.000 rs11583043 chr1:101466054 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.6 8.17 0.4 6.23e-15 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs12478296 0.591 rs7573042 chr2:242996589 A/G cg01596870 chr19:55963115 NA -0.64 -9.9 -0.47 1.71e-20 Obesity-related traits; LIHC cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg11764359 chr7:65958608 NA 0.59 6.1 0.31 2.86e-9 Diabetic kidney disease; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg16466278 chr15:43429893 TMEM62 0.53 6.1 0.31 2.83e-9 Mean platelet volume; LIHC cis rs7927771 0.524 rs2242081 chr11:47500267 T/C cg20307385 chr11:47447363 PSMC3 0.81 12.25 0.55 7.25e-29 Subjective well-being; LIHC cis rs2574704 1.000 rs6767687 chr3:11652848 A/G cg15876825 chr3:11651881 VGLL4 -0.5 -8.2 -0.41 4.88e-15 Body mass index; LIHC cis rs875971 0.756 rs4718328 chr7:65693337 A/G cg18252515 chr7:66147081 NA 0.42 5.82 0.3 1.33e-8 Aortic root size; LIHC cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg06212747 chr3:49208901 KLHDC8B 0.66 9.03 0.44 1.25e-17 Menarche (age at onset); LIHC cis rs17253792 0.545 rs17745459 chr14:56008549 T/A cg01858014 chr14:56050164 KTN1 -0.63 -6.2 -0.32 1.61e-9 Putamen volume; LIHC cis rs2408955 0.522 rs3997 chr12:48481587 T/C cg21466736 chr12:48725269 NA 0.63 9.02 0.44 1.34e-17 Glycated hemoglobin levels; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg11235426 chr6:292522 DUSP22 -0.53 -7.21 -0.36 3.61e-12 Menopause (age at onset); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg15248989 chr19:14682900 NDUFB7 0.45 6.44 0.33 4e-10 Migraine with aura; LIHC cis rs6831352 0.918 rs35662508 chr4:100050974 C/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs3806843 1.000 rs6891995 chr5:140172008 A/G cg26395211 chr5:140044315 WDR55 -0.43 -6.43 -0.33 4.19e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.83 8.27 0.41 3.09e-15 Platelet count; LIHC cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg05564831 chr3:52568323 NT5DC2 0.38 6.14 0.31 2.33e-9 Bipolar disorder; LIHC cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4906332 1.000 rs12885762 chr14:103882200 C/A cg04998671 chr14:104000505 TRMT61A -0.45 -6.28 -0.32 1.04e-9 Coronary artery disease; LIHC cis rs7909074 1.000 rs4481983 chr10:45400428 G/T cg05187965 chr10:45406764 TMEM72 -0.27 -6.85 -0.35 3.47e-11 Mean corpuscular volume; LIHC cis rs6060717 0.528 rs73905955 chr20:34332938 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.84 -0.3 1.2e-8 Hip circumference adjusted for BMI; LIHC cis rs8180040 0.764 rs13061071 chr3:47138708 G/A cg02527881 chr3:46936655 PTH1R -0.31 -6.07 -0.31 3.43e-9 Colorectal cancer; LIHC cis rs3812111 0.676 rs4946138 chr6:116469584 A/G cg08036074 chr6:116424633 NT5DC1 -0.46 -7.81 -0.39 7.15e-14 Age-related macular degeneration; LIHC cis rs2842992 0.830 rs2025190 chr6:160138241 C/T cg16489826 chr6:160211363 TCP1;MRPL18 0.53 9.38 0.45 9.41e-19 Age-related macular degeneration (geographic atrophy); LIHC cis rs2204008 0.627 rs10878488 chr12:38148666 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.16e-23 Bladder cancer; LIHC cis rs240764 0.817 rs239230 chr6:101105862 C/A cg09795085 chr6:101329169 ASCC3 0.53 7.46 0.37 7.07e-13 Neuroticism; LIHC cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg25072359 chr17:41440525 NA 0.38 6.06 0.31 3.67e-9 Menopause (age at onset); LIHC cis rs2933343 0.601 rs1680759 chr3:128594896 C/G cg25356066 chr3:128598488 ACAD9 0.55 7.66 0.38 1.9e-13 IgG glycosylation; LIHC cis rs9303401 0.659 rs34818467 chr17:56643109 C/T cg10487724 chr17:56770010 TEX14;RAD51C -0.85 -13.33 -0.58 6.33e-33 Cognitive test performance; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg21724239 chr8:58056113 NA 0.57 7.4 0.37 1.06e-12 Developmental language disorder (linguistic errors); LIHC cis rs370915 0.542 rs1895844 chr4:187833759 C/T cg19519643 chr4:187840862 NA -0.56 -9.81 -0.47 3.39e-20 Gout; LIHC cis rs41271473 0.526 rs28593014 chr1:228743576 G/A cg10167378 chr1:228756711 NA 0.64 6.52 0.33 2.58e-10 Chronic lymphocytic leukemia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25867650 chr15:75743273 SIN3A 0.44 6.14 0.32 2.26e-9 Lung function (FEV1/FVC); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15434853 chr3:52570586 NT5DC2;LOC440957 -0.43 -6.34 -0.32 7.37e-10 Cognitive function; LIHC cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg08219700 chr8:58056026 NA 0.53 6.78 0.34 5.4e-11 Developmental language disorder (linguistic errors); LIHC cis rs6598955 0.612 rs12738188 chr1:26548029 G/C cg00852783 chr1:26633632 UBXN11 0.48 8.15 0.4 6.91e-15 Obesity-related traits; LIHC cis rs4718428 1.000 rs12534637 chr7:66327654 G/C cg11764359 chr7:65958608 NA 0.49 6.41 0.33 4.95e-10 Corneal structure; LIHC cis rs4819052 0.851 rs2255774 chr21:46683851 A/T cg11663144 chr21:46675770 NA -0.32 -5.93 -0.31 7.29e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg20887711 chr4:1340912 KIAA1530 0.47 6.31 0.32 8.89e-10 Obesity-related traits; LIHC cis rs7617773 0.743 rs7621785 chr3:48343708 T/C cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs796364 1.000 rs769950 chr2:200730028 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.73 8.52 0.42 5.06e-16 Schizophrenia; LIHC cis rs1000083 0.915 rs4869152 chr5:96531607 A/G ch.5.96698337R chr5:96672581 NA 0.87 6.94 0.35 1.96e-11 Cisplatin-induced ototoxicity; LIHC cis rs9457247 0.646 rs4710160 chr6:167409241 T/A cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC cis rs4065321 0.522 rs11078930 chr17:38141955 C/T cg17467752 chr17:38218738 THRA -0.49 -8.34 -0.41 1.85e-15 White blood cell count (basophil);White blood cell count; LIHC cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg23758822 chr17:41437982 NA 0.94 17.99 0.7 2.25e-51 Menopause (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27552081 chr17:25621774 WSB1 0.38 6.5 0.33 2.9e-10 Cognitive function; LIHC cis rs35883536 0.545 rs115017855 chr1:101101830 T/A cg14515779 chr1:101123966 NA -0.59 -11.3 -0.52 2.24e-25 Monocyte count; LIHC cis rs9911578 1.000 rs9901181 chr17:56964271 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10106505 chr16:84220380 TAF1C 0.48 6.53 0.33 2.44e-10 Lung function (FEV1/FVC); LIHC cis rs7208859 0.623 rs35916850 chr17:29011173 G/A cg14067834 chr17:29058358 SUZ12P 0.62 6.08 0.31 3.18e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15527401 chr19:59071099 UBE2M;LOC100131691 0.43 6.7 0.34 8.6e-11 Cognitive function; LIHC cis rs96067 0.772 rs2231318 chr1:36602943 C/T cg24686825 chr1:36642396 MAP7D1 -0.36 -5.97 -0.31 5.95e-9 Corneal structure; LIHC cis rs7552404 1.000 rs72686191 chr1:76218319 G/T cg10523679 chr1:76189770 ACADM 0.63 8.5 0.42 6e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1670533 0.932 rs2045067 chr4:1052355 C/T cg27284194 chr4:1044797 NA 0.6 8.99 0.44 1.67e-17 Recombination rate (females); LIHC cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 8.96 0.44 2.22e-17 Bipolar disorder; LIHC cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.14 0.55 1.97e-28 Prudent dietary pattern; LIHC cis rs1005277 0.579 rs2505237 chr10:38438898 T/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs1395 0.710 rs2083363 chr2:27475318 G/C cg22903471 chr2:27725779 GCKR -0.4 -6.0 -0.31 4.95e-9 Blood metabolite levels; LIHC cis rs10751667 0.666 rs12295141 chr11:947065 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.12 0.48 3.02e-21 Alzheimer's disease (late onset); LIHC cis rs2797160 0.904 rs1418637 chr6:125992553 A/G cg05901451 chr6:126070800 HEY2 -0.47 -7.64 -0.38 2.18e-13 Endometrial cancer; LIHC cis rs6952808 0.792 rs2056481 chr7:1955435 A/G cg04267008 chr7:1944627 MAD1L1 -0.71 -11.39 -0.52 1.05e-25 Bipolar disorder and schizophrenia; LIHC cis rs4819052 0.851 rs8130285 chr21:46671701 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.82 0.39 6.79e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9287719 0.674 rs11691060 chr2:10827061 T/C cg02829992 chr2:10710499 NA 0.39 6.01 0.31 4.75e-9 Prostate cancer; LIHC cis rs6430585 0.528 rs309166 chr2:136667487 C/T cg07169764 chr2:136633963 MCM6 0.97 14.86 0.63 6.81e-39 Corneal structure; LIHC cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg23172400 chr8:95962367 TP53INP1 -0.41 -9.47 -0.46 4.58e-19 Type 2 diabetes; LIHC cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg06634786 chr22:41940651 POLR3H 0.73 7.51 0.38 5.22e-13 Vitiligo; LIHC cis rs61712019 0.679 rs11126611 chr2:77714052 T/C cg11252801 chr2:77748917 LRRTM4 0.55 7.61 0.38 2.76e-13 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg02429669 chr19:52430771 ZNF613 0.48 6.71 0.34 8.26e-11 Lung function (FEV1/FVC); LIHC cis rs17401966 1.000 rs58549151 chr1:10314657 A/C cg19773385 chr1:10388646 KIF1B -0.48 -8.21 -0.41 4.66e-15 Hepatocellular carcinoma; LIHC cis rs778371 0.649 rs13021823 chr2:233686862 A/G cg08000102 chr2:233561755 GIGYF2 -0.76 -9.18 -0.44 4.18e-18 Schizophrenia; LIHC cis rs17376456 0.877 rs2290937 chr5:93356515 A/T cg25358565 chr5:93447407 FAM172A 1.11 10.02 0.48 6.95e-21 Diabetic retinopathy; LIHC cis rs1552244 0.882 rs36006511 chr3:10054191 C/T cg08888203 chr3:10149979 C3orf24 0.49 6.12 0.31 2.5e-9 Alzheimer's disease; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg16572859 chr19:18263815 PIK3R2 -0.51 -6.42 -0.33 4.43e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs8180040 0.726 rs11130110 chr3:47000606 T/C cg27129171 chr3:47204927 SETD2 0.62 10.79 0.5 1.46e-23 Colorectal cancer; LIHC cis rs12478296 0.892 rs60545379 chr2:243034390 A/T cg06360820 chr2:242988706 NA -0.82 -11.57 -0.53 2.43e-26 Obesity-related traits; LIHC cis rs11190604 1.000 rs3750633 chr10:102308214 C/T cg07080220 chr10:102295463 HIF1AN 0.58 8.08 0.4 1.09e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs12744310 0.887 rs12042464 chr1:41786854 A/G cg03962019 chr1:41807865 NA -0.38 -6.14 -0.32 2.25e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11098499 0.954 rs1546505 chr4:120241224 A/G cg09307838 chr4:120376055 NA 0.75 11.34 0.52 1.68e-25 Corneal astigmatism; LIHC cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20227212 chr21:18984006 BTG3 0.51 7.53 0.38 4.46e-13 Cognitive function; LIHC cis rs763121 0.853 rs6001214 chr22:39149155 C/T cg06022373 chr22:39101656 GTPBP1 0.68 12.33 0.55 3.89e-29 Menopause (age at onset); LIHC cis rs295140 0.710 rs1729421 chr2:201080113 G/C cg23649088 chr2:200775458 C2orf69 0.44 5.92 0.3 7.78e-9 QT interval; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10570662 chr22:19159548 NA 0.46 6.08 0.31 3.19e-9 Lung function (FEV1/FVC); LIHC cis rs7959452 0.535 rs10878953 chr12:69674187 A/G cg22834771 chr12:69754056 YEATS4 -0.51 -8.88 -0.43 3.98e-17 Blood protein levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg22922403 chr8:145650096 VPS28 0.39 6.33 0.32 7.66e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs2180341 1.000 rs6569477 chr6:127589302 T/A cg24812749 chr6:127587940 RNF146 1.06 15.66 0.65 4.81e-42 Breast cancer; LIHC cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs74417235 0.684 rs13179754 chr5:154059845 C/T cg08754654 chr5:154026448 NA 0.31 7.19 0.36 4.19e-12 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs2933343 0.621 rs6764682 chr3:128568383 G/A cg25356066 chr3:128598488 ACAD9 -0.53 -7.2 -0.36 3.89e-12 IgG glycosylation; LIHC cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs4660261 0.561 rs11210934 chr1:44369435 G/A cg12908607 chr1:44402522 ARTN -0.5 -8.45 -0.42 8.52e-16 Intelligence (multi-trait analysis); LIHC cis rs950169 0.580 rs11634322 chr15:85172209 C/T cg03959625 chr15:84868606 LOC388152 0.43 6.1 0.31 2.8e-9 Schizophrenia; LIHC cis rs68170813 0.605 rs4730227 chr7:106904031 G/C cg02696742 chr7:106810147 HBP1 -0.53 -6.22 -0.32 1.44e-9 Coronary artery disease; LIHC cis rs7582720 1.000 rs72932557 chr2:203846817 A/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs36051895 0.632 rs7040922 chr9:5174829 A/G cg02405213 chr9:5042618 JAK2 0.65 11.91 0.54 1.36e-27 Pediatric autoimmune diseases; LIHC cis rs9733 0.744 rs3754211 chr1:150951857 G/A cg17724175 chr1:150552817 MCL1 0.33 6.22 0.32 1.46e-9 Tonsillectomy; LIHC cis rs3540 0.554 rs4244879 chr15:91066915 C/T cg22089800 chr15:90895588 ZNF774 -0.57 -7.84 -0.39 5.85e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs12744310 0.887 rs12732820 chr1:41798773 C/T cg03962019 chr1:41807865 NA 0.38 6.18 0.32 1.78e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs4243830 0.826 rs12565181 chr1:6620545 G/A cg22792644 chr1:6614718 TAS1R1;NOL9 0.98 11.65 0.53 1.22e-26 Body mass index; LIHC cis rs10916814 0.959 rs12037522 chr1:20900184 A/T cg24502330 chr1:20914028 CDA -0.28 -5.86 -0.3 1.1e-8 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs10733682 0.715 rs3814119 chr9:129462901 A/G cg00232160 chr9:129468157 NA 0.37 6.63 0.34 1.34e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2274273 0.805 rs11628437 chr14:55775468 G/A cg01864836 chr14:55583639 NA -0.37 -6.55 -0.33 2.17e-10 Protein biomarker; LIHC cis rs12477438 0.561 rs2084988 chr2:99655755 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.52 -7.56 -0.38 3.69e-13 Chronic sinus infection; LIHC cis rs1865760 1.000 rs3830057 chr6:25918510 G/T cg03264133 chr6:25882463 NA -0.38 -5.72 -0.3 2.36e-8 Height; LIHC cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg01860168 chr7:100026446 MEPCE;ZCWPW1 0.6 5.86 0.3 1.11e-8 Platelet count; LIHC cis rs921968 0.509 rs626432 chr2:219355658 C/A cg02176678 chr2:219576539 TTLL4 0.51 7.07 0.36 8.59e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs4845459 0.967 rs6700160 chr1:152593024 A/C cg18116418 chr1:152553244 LCE3D -0.31 -5.74 -0.3 2.14e-8 Psoriasis; LIHC cis rs227584 0.501 rs62078931 chr17:42198059 A/C cg08499158 chr17:42289980 UBTF 0.41 6.62 0.34 1.4e-10 Bone mineral density (hip);Bone mineral density; LIHC cis rs6089584 0.853 rs1740367 chr20:60574834 C/T cg13770153 chr20:60521292 NA -0.37 -7.1 -0.36 7.46e-12 Body mass index; LIHC cis rs67460515 0.500 rs964533 chr3:160749019 C/A cg17135325 chr3:160939158 NMD3 0.44 5.94 0.31 7.03e-9 Parkinson's disease; LIHC cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg06640241 chr16:89574553 SPG7 0.87 16.36 0.66 7.55e-45 Multiple myeloma (IgH translocation); LIHC cis rs9381040 0.610 rs4140579 chr6:41041752 G/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.37 -5.86 -0.3 1.08e-8 Alzheimer's disease (late onset); LIHC cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg25894440 chr7:65020034 NA -0.55 -6.44 -0.33 4.02e-10 Diabetic kidney disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00920043 chr1:11333412 UBIAD1 0.44 6.58 0.34 1.76e-10 Pancreatic cancer; LIHC cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg16262614 chr3:133464971 TF 0.28 6.39 0.33 5.36e-10 Iron status biomarkers; LIHC cis rs7917772 0.536 rs17783771 chr10:104410736 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.75 8.73 0.43 1.16e-16 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs6977660 0.714 rs10252597 chr7:19791171 G/T cg07541023 chr7:19748670 TWISTNB -0.51 -7.86 -0.39 4.99e-14 Thyroid stimulating hormone; LIHC cis rs853679 0.517 rs4713137 chr6:28083521 C/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.61e-10 Depression; LIHC cis rs644799 0.965 rs11021310 chr11:95502106 A/C cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.05 0.68 1.26e-47 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs11122272 0.735 rs2491408 chr1:231519248 C/G cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs7223966 1.000 rs11871767 chr17:61698723 A/G cg05941027 chr17:61774174 LIMD2 0.35 7.36 0.37 1.4e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6430585 0.583 rs730005 chr2:136582694 T/C cg15123519 chr2:136567270 LCT -0.39 -6.04 -0.31 4.01e-9 Corneal structure; LIHC cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg19318889 chr4:1322082 MAEA 0.42 5.77 0.3 1.81e-8 Obesity-related traits; LIHC cis rs1336900 0.544 rs10888386 chr1:150611957 A/G cg17724175 chr1:150552817 MCL1 -0.54 -11.15 -0.52 7.94e-25 Blood protein levels; LIHC cis rs1348850 0.914 rs8941 chr2:178406481 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.37 0.59 4.18e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs801193 1.000 rs3800812 chr7:66223461 T/C cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.63e-9 Aortic root size; LIHC trans rs3858145 0.588 rs115455464 chr10:70038498 T/C cg04882175 chr6:131122610 NA -0.48 -6.06 -0.31 3.5e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs7208859 0.562 rs8078897 chr17:29106257 T/G cg13385521 chr17:29058706 SUZ12P 0.83 8.22 0.41 4.3e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4589502 0.502 rs2169460 chr15:67197240 A/G cg09911534 chr15:67153556 NA 0.36 5.75 0.3 2e-8 Lung cancer (smoking interaction); LIHC trans rs12478296 1.000 rs66466023 chr2:243046151 T/G cg01596870 chr19:55963115 NA -0.64 -8.49 -0.42 6.49e-16 Obesity-related traits; LIHC cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.56e-48 Diabetic kidney disease; LIHC cis rs2732480 0.577 rs2634693 chr12:48706498 C/T cg21466736 chr12:48725269 NA -0.71 -10.62 -0.5 5.95e-23 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs881375 0.867 rs10818484 chr9:123661194 C/T cg14580859 chr9:123691850 NA 0.39 6.76 0.34 5.9e-11 Rheumatoid arthritis; LIHC cis rs36051895 0.632 rs62541899 chr9:5143291 C/T cg02405213 chr9:5042618 JAK2 -0.65 -10.94 -0.51 4.23e-24 Pediatric autoimmune diseases; LIHC cis rs9916302 0.808 rs12948906 chr17:37644854 C/T cg00129232 chr17:37814104 STARD3 -0.42 -6.81 -0.35 4.45e-11 Glomerular filtration rate (creatinine); LIHC cis rs9517320 0.534 rs9554474 chr13:99140871 G/A cg20487152 chr13:99095054 FARP1 -0.39 -6.62 -0.34 1.37e-10 Longevity; LIHC cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.91 8.23 0.41 3.98e-15 Platelet count; LIHC cis rs1799949 0.931 rs34474989 chr17:41445410 A/T cg25072359 chr17:41440525 NA 0.38 6.07 0.31 3.46e-9 Menopause (age at onset); LIHC trans rs2727020 0.704 rs2988340 chr11:49176057 C/T cg15704280 chr7:45808275 SEPT13 -0.84 -15.13 -0.63 6.17e-40 Coronary artery disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12252866 chr3:50263686 NA -0.47 -6.71 -0.34 8.26e-11 Pancreatic cancer; LIHC cis rs10744422 1.000 rs12255 chr12:123350204 C/T cg22842854 chr12:123319900 HIP1R -0.63 -7.92 -0.39 3.47e-14 Schizophrenia; LIHC cis rs10463316 0.817 rs6897109 chr5:150777738 T/C cg03212797 chr5:150827313 SLC36A1 -0.41 -6.19 -0.32 1.76e-9 Metabolite levels (Pyroglutamine); LIHC cis rs2070488 0.662 rs6599202 chr3:38480651 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.58 8.13 0.4 7.92e-15 Electrocardiographic conduction measures; LIHC cis rs10911251 0.528 rs10911264 chr1:183115040 G/A ch.1.3577855R chr1:183094577 LAMC1 0.62 10.61 0.5 6.15e-23 Colorectal cancer; LIHC trans rs875971 1.000 rs6958271 chr7:65979331 A/C cg10756647 chr7:56101905 PSPH 0.44 6.43 0.33 4.28e-10 Aortic root size; LIHC cis rs12893668 0.703 rs4906336 chr14:104033265 C/G cg24130564 chr14:104152367 KLC1 -0.55 -8.87 -0.43 4.23e-17 Reticulocyte count; LIHC cis rs11122272 0.735 rs2486733 chr1:231531465 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 7.1e-23 Hemoglobin concentration; LIHC cis rs250677 0.687 rs250673 chr5:148445798 C/T cg12140854 chr5:148520817 ABLIM3 -0.46 -6.23 -0.32 1.37e-9 Breast cancer; LIHC cis rs965469 0.947 rs56689368 chr20:3332921 G/A cg25506879 chr20:3388711 C20orf194 -0.57 -6.88 -0.35 2.95e-11 IFN-related cytopenia; LIHC trans rs561341 1.000 rs1557731 chr17:30321567 T/G cg20587970 chr11:113659929 NA -1.23 -10.64 -0.5 5.12e-23 Hip circumference adjusted for BMI; LIHC cis rs769267 0.930 rs1047361 chr19:19606634 G/A cg03709012 chr19:19516395 GATAD2A 1.0 18.21 0.7 2.91e-52 Tonsillectomy; LIHC cis rs769267 0.965 rs4808938 chr19:19401218 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.6 9.48 0.46 4.3e-19 Tonsillectomy; LIHC cis rs2204008 0.754 rs11514074 chr12:38401128 C/T cg26384229 chr12:38710491 ALG10B 0.84 10.51 0.49 1.45e-22 Bladder cancer; LIHC cis rs6565681 1.000 rs4889848 chr17:78354661 C/T cg15383979 chr17:78362278 RNF213;LOC100294362 -0.54 -7.53 -0.38 4.49e-13 Moyamoya disease; LIHC cis rs1348850 0.872 rs4893825 chr2:178298687 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.91 14.42 0.61 3.62e-37 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs780096 0.526 rs780102 chr2:27659491 T/C cg22903471 chr2:27725779 GCKR -0.5 -8.69 -0.43 1.54e-16 Total body bone mineral density; LIHC cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.84 8.11 0.4 9.44e-15 Platelet count; LIHC trans rs6598955 0.671 rs12086573 chr1:26574330 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.79 -8.78 -0.43 8.23e-17 Obesity-related traits; LIHC cis rs2404602 0.530 rs11072614 chr15:76967205 G/A cg23625390 chr15:77176239 SCAPER -0.47 -7.54 -0.38 4.15e-13 Blood metabolite levels; LIHC cis rs9916302 0.904 rs801420 chr17:37466103 C/G cg07936489 chr17:37558343 FBXL20 0.84 13.75 0.6 1.53e-34 Glomerular filtration rate (creatinine); LIHC trans rs801193 1.000 rs10252765 chr7:66228732 C/G cg26939375 chr7:64535504 NA 0.42 6.76 0.34 5.85e-11 Aortic root size; LIHC cis rs10242455 0.702 rs73403290 chr7:99157828 C/T cg18809830 chr7:99032528 PTCD1 -0.9 -6.93 -0.35 2.13e-11 Blood metabolite levels; LIHC cis rs4843747 0.708 rs11866437 chr16:88072279 A/G cg06050784 chr16:88016603 BANP -0.44 -7.73 -0.39 1.19e-13 Menopause (age at onset); LIHC cis rs922107 0.738 rs12410923 chr1:90035786 G/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.67 -0.38 1.79e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs8053891 0.906 rs28714527 chr16:71997862 C/G cg01557791 chr16:72042693 DHODH -0.42 -6.12 -0.31 2.57e-9 Coronary artery disease; LIHC cis rs6754311 0.773 rs666407 chr2:136640233 A/G cg15123519 chr2:136567270 LCT -0.4 -8.16 -0.4 6.46e-15 Mosquito bite size; LIHC cis rs1843834 0.755 rs10194591 chr2:225574276 T/A cg22509189 chr2:225307070 NA -0.44 -5.75 -0.3 2e-8 IgE levels in asthmatics (D.p. specific); LIHC cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg16680214 chr1:154839983 KCNN3 -0.34 -5.91 -0.3 8.46e-9 Prostate cancer; LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg14666006 chr8:27629879 CCDC25 -0.66 -6.93 -0.35 2.14e-11 Obesity-related traits; LIHC cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg05064044 chr6:292385 DUSP22 -0.52 -6.83 -0.35 3.99e-11 Menopause (age at onset); LIHC cis rs17102884 0.506 rs887746 chr14:75403817 C/T cg11812906 chr14:75593930 NEK9 -0.46 -7.74 -0.39 1.17e-13 Neuroticism; LIHC trans rs801193 1.000 rs2420824 chr7:66131116 G/A cg26939375 chr7:64535504 NA -0.4 -6.43 -0.33 4.39e-10 Aortic root size; LIHC cis rs10751667 0.600 rs10751672 chr11:948712 T/C cg10932868 chr11:921992 NA 0.38 7.14 0.36 5.52e-12 Alzheimer's disease (late onset); LIHC trans rs11098499 0.691 rs12502524 chr4:120271414 G/A cg25214090 chr10:38739885 LOC399744 0.44 7.28 0.37 2.26e-12 Corneal astigmatism; LIHC cis rs2228479 0.702 rs62053701 chr16:89860584 G/A cg19635926 chr16:89946313 TCF25 0.55 6.84 0.35 3.57e-11 Skin colour saturation; LIHC cis rs12971120 0.891 rs71359051 chr18:72169723 G/A cg25817165 chr18:72167213 CNDP2 -0.71 -12.43 -0.56 1.54e-29 Refractive error; LIHC cis rs7617480 0.648 rs9859473 chr3:48837182 A/G cg07636037 chr3:49044803 WDR6 0.76 9.31 0.45 1.56e-18 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs8078723 0.701 rs2305482 chr17:38140927 A/C cg17344932 chr17:38183730 MED24;SNORD124 0.62 10.5 0.49 1.56e-22 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs1892700 0.801 rs62226456 chr21:34867845 C/G cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.97e-8 Educational attainment; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20696051 chr7:158649028 WDR60 0.46 6.35 0.32 6.69e-10 Pancreatic cancer; LIHC cis rs6499255 1.000 rs4985523 chr16:69797192 T/A cg15192750 chr16:69999425 NA 0.47 7.12 0.36 6.49e-12 IgE levels; LIHC cis rs9513627 0.573 rs12431100 chr13:100184918 C/G cg25919922 chr13:100150906 NA -1.04 -16.12 -0.66 6.79e-44 Obesity-related traits; LIHC cis rs2180341 0.782 rs6912006 chr6:127722631 C/T cg27446573 chr6:127587934 RNF146 0.62 10.0 0.48 7.84e-21 Breast cancer; LIHC cis rs6459788 0.720 rs11768765 chr7:157253133 C/T cg06271696 chr7:157225062 NA -0.49 -7.98 -0.4 2.24e-14 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs7552404 0.731 rs10873808 chr1:76406767 T/C cg03433033 chr1:76189801 ACADM 0.58 6.82 0.35 4.23e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2153535 0.580 rs9406143 chr6:8444583 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs67614146 1 rs67614146 chr6:87821827 AC/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.35 -6.73 -0.34 7.35e-11 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs936229 1.000 rs4886615 chr15:75131661 A/G cg14664628 chr15:75095509 CSK -0.87 -14.94 -0.63 3.35e-39 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs4073582 0.595 rs801741 chr11:65917084 A/G cg16950941 chr11:66035639 RAB1B 0.57 8.58 0.42 3.39e-16 Gout; LIHC cis rs7208859 0.623 rs73271869 chr17:29152221 G/A cg14067834 chr17:29058358 SUZ12P 0.69 6.69 0.34 9.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs780096 0.587 rs10205219 chr2:27568565 T/C cg27432699 chr2:27873401 GPN1 -0.48 -6.92 -0.35 2.3e-11 Total body bone mineral density; LIHC cis rs7119038 0.818 rs11217042 chr11:118682528 G/A cg19308663 chr11:118741387 NA 0.39 6.08 0.31 3.21e-9 Sjögren's syndrome; LIHC cis rs9549367 0.789 rs6577031 chr13:113878182 T/C cg00898013 chr13:113819073 PROZ 0.34 6.26 0.32 1.14e-9 Platelet distribution width; LIHC cis rs2243480 1.000 rs778729 chr7:65824419 T/C cg07424592 chr7:64974309 NA 0.78 9.02 0.44 1.34e-17 Diabetic kidney disease; LIHC cis rs9814567 1.000 rs6787371 chr3:134254991 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.27 -0.55 6.44e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg21724239 chr8:58056113 NA 0.48 6.4 0.33 5.2400000000000005e-10 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.798 rs13409996 chr2:99575497 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.06 -0.51 1.7e-24 Chronic sinus infection; LIHC cis rs2239547 0.522 rs2581780 chr3:53058960 C/T cg11645453 chr3:52864694 ITIH4 -0.22 -5.71 -0.3 2.43e-8 Schizophrenia; LIHC cis rs2302190 0.769 rs7215531 chr17:56493374 A/T cg12560992 chr17:57184187 TRIM37 0.69 8.62 0.42 2.53e-16 Vitamin D levels; LIHC cis rs1008375 0.966 rs3775925 chr4:17588437 A/G cg02297831 chr4:17616191 MED28 0.47 7.17 0.36 4.76e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10779751 1.000 rs2253213 chr1:11265785 A/G cg08854313 chr1:11322531 MTOR 0.78 10.86 0.51 8.57e-24 Body mass index; LIHC cis rs6598955 0.724 rs12732295 chr1:26602251 C/T cg04990556 chr1:26633338 UBXN11 -0.61 -10.03 -0.48 6.46e-21 Obesity-related traits; LIHC cis rs561341 0.883 rs4450460 chr17:30201309 C/T cg13647721 chr17:30228624 UTP6 -0.74 -7.1 -0.36 7.45e-12 Hip circumference adjusted for BMI; LIHC cis rs36051895 0.559 rs7858422 chr9:5209797 G/T cg02405213 chr9:5042618 JAK2 -0.61 -10.32 -0.49 6.24e-22 Pediatric autoimmune diseases; LIHC cis rs1949733 1.000 rs2631758 chr4:8495304 G/A cg11789530 chr4:8429930 ACOX3 -0.82 -12.05 -0.55 4.24e-28 Response to antineoplastic agents; LIHC cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg26338869 chr17:61819248 STRADA -0.48 -6.81 -0.35 4.52e-11 Prudent dietary pattern; LIHC trans rs875971 1.000 rs12532998 chr7:65967459 A/C cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.09e-10 Aortic root size; LIHC cis rs826838 0.967 rs11168299 chr12:38902028 G/T cg13010199 chr12:38710504 ALG10B 0.61 7.49 0.38 6.09e-13 Heart rate; LIHC cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg06481639 chr22:41940642 POLR3H 0.71 7.06 0.36 9.26e-12 Vitiligo; LIHC cis rs9513627 1.000 rs7996624 chr13:100127541 G/T cg25919922 chr13:100150906 NA -0.77 -6.89 -0.35 2.74e-11 Obesity-related traits; LIHC cis rs897984 0.646 rs9938088 chr16:30830004 G/A cg02466173 chr16:30829666 NA -0.47 -7.82 -0.39 6.63e-14 Dementia with Lewy bodies; LIHC cis rs6964587 1.000 rs7455444 chr7:91639313 C/T cg17063962 chr7:91808500 NA 1.02 19.5 0.73 1.81e-57 Breast cancer; LIHC cis rs870825 0.860 rs55974219 chr4:185600733 G/A cg04058563 chr4:185651563 MLF1IP 0.84 7.01 0.35 1.31e-11 Blood protein levels; LIHC cis rs6933660 0.800 rs3800273 chr6:151759035 G/C cg14262678 chr6:151773367 RMND1;C6orf211 0.51 7.48 0.38 6.26e-13 Menarche (age at onset); LIHC cis rs10744422 1.000 rs10847869 chr12:123328359 C/G cg07706471 chr12:123319906 HIP1R -0.57 -7.62 -0.38 2.57e-13 Schizophrenia; LIHC cis rs67478160 0.643 rs11626377 chr14:104234357 G/A cg08213375 chr14:104286397 PPP1R13B 0.66 13.06 0.58 6.68e-32 Schizophrenia; LIHC cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg10130564 chr11:117069849 TAGLN 0.37 6.3 0.32 9.09e-10 Blood protein levels; LIHC cis rs17253792 0.545 rs12879564 chr14:56017694 A/G cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs11190604 1.000 rs11190587 chr10:102266638 C/T cg07080220 chr10:102295463 HIF1AN 0.57 8.18 0.4 5.52e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1577917 1.000 rs12208493 chr6:86662267 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.58 -10.14 -0.48 2.69e-21 Response to antipsychotic treatment; LIHC cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg00149659 chr3:10157352 C3orf10 0.68 7.11 0.36 6.86e-12 Alzheimer's disease; LIHC cis rs9549367 0.865 rs3861721 chr13:113906308 C/T cg00898013 chr13:113819073 PROZ -0.42 -7.18 -0.36 4.24e-12 Platelet distribution width; LIHC cis rs11112613 0.609 rs11112636 chr12:106047204 G/A cg03607813 chr12:105948248 NA 0.44 6.89 0.35 2.7e-11 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs595982 0.546 rs10401443 chr19:49402059 C/A cg21252483 chr19:49399788 TULP2 -0.61 -9.7 -0.46 8.03e-20 Red cell distribution width; LIHC cis rs11122272 0.735 rs2790884 chr1:231531932 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.6 -0.5 6.98e-23 Hemoglobin concentration; LIHC cis rs12926788 0.689 rs34365165 chr16:24856208 G/A cg04756594 chr16:24857601 SLC5A11 0.48 6.68 0.34 9.71e-11 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs611744 0.837 rs422847 chr8:109103274 C/T cg21045802 chr8:109455806 TTC35 -0.48 -8.25 -0.41 3.44e-15 Dupuytren's disease; LIHC cis rs10078 0.571 rs890973 chr5:471494 T/C cg26072250 chr5:443457 EXOC3;C5orf55 0.75 10.04 0.48 5.94e-21 Fat distribution (HIV); LIHC cis rs911555 0.655 rs10141157 chr14:104018105 T/C cg24130564 chr14:104152367 KLC1 -0.45 -7.58 -0.38 3.19e-13 Intelligence (multi-trait analysis); LIHC cis rs1949733 0.656 rs2688224 chr4:8404700 C/G cg11789530 chr4:8429930 ACOX3 0.76 11.21 0.52 4.7e-25 Response to antineoplastic agents; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg22379573 chr1:197704774 DENND1B 0.4 6.51 0.33 2.68e-10 Longevity; LIHC cis rs240764 0.658 rs4571568 chr6:101223955 T/A cg09795085 chr6:101329169 ASCC3 -0.54 -7.57 -0.38 3.57e-13 Neuroticism; LIHC cis rs12744310 1.000 rs56381773 chr1:41770718 T/C cg03962019 chr1:41807865 NA 0.4 6.4 0.33 5.18e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs12249377 0.519 rs7087400 chr10:92587180 A/G cg14313238 chr10:92632228 RPP30 0.38 6.37 0.33 5.94e-10 White matter microstructure (global fractional anisotropy); LIHC trans rs6563898 0.869 rs7194029 chr16:83349398 T/C cg13016115 chr14:23388406 RBM23 0.41 6.29 0.32 9.61e-10 IgE levels in asthmatics (D.f. specific); LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg14671364 chr1:107599128 PRMT6 -0.54 -7.93 -0.39 3.08e-14 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs1552244 0.882 rs34779351 chr3:10021801 A/G cg08888203 chr3:10149979 C3orf24 0.47 6.11 0.31 2.76e-9 Alzheimer's disease; LIHC cis rs7412746 0.658 rs2272214 chr1:150931462 C/T cg18016565 chr1:150552671 MCL1 0.49 9.49 0.46 4.15e-19 Melanoma; LIHC cis rs11122272 0.735 rs910824 chr1:231498773 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.83 -0.51 1.06e-23 Hemoglobin concentration; LIHC cis rs7937682 0.883 rs1612013 chr11:111456293 A/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.84 -0.51 1.02e-23 Primary sclerosing cholangitis; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg03874509 chr1:107600012 PRMT6 -0.75 -11.82 -0.54 2.81e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs477895 0.838 rs12794145 chr11:64006484 C/T cg18225595 chr11:63971243 STIP1 0.64 7.86 0.39 5.1e-14 Mean platelet volume; LIHC cis rs11098699 1.000 rs11098699 chr4:124171834 C/G cg09941581 chr4:124220074 SPATA5 0.31 5.75 0.3 1.99e-8 Mosquito bite size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00345230 chr4:151936469 LRBA 0.46 6.25 0.32 1.22e-9 Lung function (FEV1/FVC); LIHC cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg00684032 chr4:1343700 KIAA1530 0.5 7.3 0.37 2.01e-12 Obesity-related traits; LIHC cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs743757 1.000 rs734767 chr3:50431410 C/G cg08207895 chr3:50388901 TUSC4;CYB561D2 0.51 8.05 0.4 1.36e-14 Diastolic blood pressure; LIHC cis rs992157 0.798 rs7587220 chr2:219160864 C/A cg20019365 chr2:219134978 PNKD;AAMP -0.76 -12.01 -0.54 5.9e-28 Colorectal cancer; LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg26338869 chr17:61819248 STRADA -0.45 -6.29 -0.32 9.77e-10 Prudent dietary pattern; LIHC cis rs2153535 0.563 rs6942177 chr6:8534460 A/G cg23788917 chr6:8435910 SLC35B3 -0.65 -9.24 -0.45 2.72e-18 Motion sickness; LIHC cis rs2455601 0.608 rs11042104 chr11:8890924 C/G cg21881798 chr11:8931708 C11orf17;ST5 0.48 8.25 0.41 3.46e-15 Schizophrenia; LIHC cis rs12586317 0.547 rs3759548 chr14:35450333 C/T cg16230307 chr14:35515116 FAM177A1 0.79 12.74 0.57 1.06e-30 Psoriasis; LIHC cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.04 0.31 3.91e-9 Menopause (age at onset); LIHC cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg11663144 chr21:46675770 NA -0.32 -5.86 -0.3 1.12e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6442522 0.678 rs878945 chr3:15509327 C/G cg16303742 chr3:15540471 COLQ 0.46 7.81 0.39 6.93e-14 Uric acid levels; LIHC trans rs12960119 0.536 rs12960532 chr18:23726995 A/G cg05333146 chr16:67183725 B3GNT9 0.64 6.06 0.31 3.57e-9 Rhegmatogenous retinal detachment; LIHC cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg06481639 chr22:41940642 POLR3H 0.6 5.77 0.3 1.81e-8 Vitiligo; LIHC trans rs1814175 0.817 rs10839397 chr11:49857074 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.7 -0.79 3.61e-74 Height; LIHC cis rs7927771 1.000 rs11039255 chr11:47495746 G/T cg20135002 chr11:47629003 NA -0.57 -9.76 -0.47 5e-20 Subjective well-being; LIHC cis rs7772486 0.875 rs7761033 chr6:146356106 C/T cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6430585 0.528 rs3098102 chr2:136654833 C/T cg07169764 chr2:136633963 MCM6 0.96 14.61 0.62 6.72e-38 Corneal structure; LIHC cis rs28595532 0.800 rs67686161 chr4:119336720 C/T cg21605333 chr4:119757512 SEC24D 0.97 8.11 0.4 9.41e-15 Cannabis dependence symptom count; LIHC cis rs2463822 1.000 rs115395195 chr11:62100353 G/A cg06239285 chr11:62104954 ASRGL1 -0.94 -6.3 -0.32 9.34e-10 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs8062405 0.723 rs62031562 chr16:28609329 A/T cg00204512 chr16:28754710 NA 0.42 7.07 0.36 8.69e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7639513 0.545 rs12714874 chr3:12719928 C/T cg23032965 chr3:12705835 RAF1 0.6 6.58 0.34 1.77e-10 Itch intensity from mosquito bite; LIHC cis rs17685 0.753 rs1639609 chr7:75683581 T/C cg16684958 chr7:75615977 POR 0.52 8.81 0.43 6.47e-17 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2180341 0.920 rs9401951 chr6:127671632 A/C cg24812749 chr6:127587940 RNF146 1.05 15.38 0.64 6.23e-41 Breast cancer; LIHC cis rs738322 0.839 rs9607517 chr22:38596100 G/A cg25457927 chr22:38595422 NA 0.34 8.41 0.41 1.1e-15 Cutaneous nevi; LIHC cis rs8180040 0.654 rs11714373 chr3:47214817 G/A cg27129171 chr3:47204927 SETD2 -0.59 -9.77 -0.47 4.71e-20 Colorectal cancer; LIHC cis rs9616064 0.506 rs737135 chr22:47061791 C/T cg05621596 chr22:47072043 GRAMD4 -0.6 -9.48 -0.46 4.39e-19 Urate levels in obese individuals; LIHC cis rs950169 1.000 rs11638394 chr15:84778928 G/A cg17507749 chr15:85114479 UBE2QP1 0.76 7.75 0.39 1.03e-13 Schizophrenia; LIHC trans rs11098499 0.754 rs2036857 chr4:120249240 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.24 0.41 3.62e-15 Corneal astigmatism; LIHC cis rs7116495 0.737 rs7126838 chr11:71826237 A/G cg26138937 chr11:71823887 C11orf51 0.82 8.33 0.41 2.03e-15 Severe influenza A (H1N1) infection; LIHC cis rs1005277 0.579 rs116912400 chr10:38479207 G/T cg25427524 chr10:38739819 LOC399744 -0.72 -14.26 -0.61 1.58e-36 Extrinsic epigenetic age acceleration; LIHC cis rs2839186 0.605 rs2839173 chr21:47676711 G/A cg20399509 chr21:47717575 C21orf57 -0.37 -5.97 -0.31 5.88e-9 Testicular germ cell tumor; LIHC cis rs9733 0.596 rs2065900 chr1:150652202 A/G cg18016565 chr1:150552671 MCL1 0.59 11.57 0.53 2.34e-26 Tonsillectomy; LIHC cis rs1008375 0.863 rs2058336 chr4:17608299 T/C cg02297831 chr4:17616191 MED28 0.45 6.96 0.35 1.76e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs801193 0.569 rs3846973 chr7:66120035 T/C cg18876405 chr7:65276391 NA -0.32 -5.93 -0.31 7.45e-9 Aortic root size; LIHC cis rs4908760 0.868 rs12131864 chr1:8591162 A/G cg20416874 chr1:8611966 RERE -0.69 -14.66 -0.62 4.08e-38 Vitiligo; LIHC cis rs6570726 0.967 rs9497316 chr6:145792387 G/T cg23711669 chr6:146136114 FBXO30 -0.51 -8.79 -0.43 7.62e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs2274273 0.934 rs10137307 chr14:55845185 T/C cg01864836 chr14:55583639 NA -0.38 -6.67 -0.34 1.01e-10 Protein biomarker; LIHC cis rs6782228 0.606 rs2811490 chr3:128351755 C/T cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg08677398 chr8:58056175 NA 0.41 6.38 0.33 5.63e-10 Developmental language disorder (linguistic errors); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg10205151 chr7:931109 C7orf20 0.5 6.23 0.32 1.34e-9 Lung function (FEV1); LIHC cis rs9640161 0.663 rs1916932 chr7:150021644 T/C cg10018233 chr7:150070692 REPIN1 0.57 9.63 0.46 1.4e-19 Blood protein levels;Circulating chemerin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20488697 chr17:79885644 LOC92659;MAFG 0.49 7.31 0.37 1.95e-12 Pancreatic cancer; LIHC cis rs1570884 0.516 rs9526580 chr13:50164023 C/G cg03651054 chr13:50194643 NA -0.34 -6.15 -0.32 2.12e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs727563 0.593 rs132770 chr22:42017264 A/G cg03806693 chr22:41940476 POLR3H 0.99 10.8 0.5 1.34e-23 Crohn's disease;Inflammatory bowel disease; LIHC cis rs249954 0.512 rs34514 chr16:23670597 G/A cg01460202 chr16:23706506 ERN2 0.36 5.97 0.31 5.9e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs11098499 0.708 rs10005237 chr4:120237897 T/C cg25214090 chr10:38739885 LOC399744 0.53 8.56 0.42 3.89e-16 Corneal astigmatism; LIHC cis rs10792665 0.934 rs10751083 chr11:82660359 C/G cg24227371 chr11:82718527 RAB30 0.31 7.19 0.36 4.14e-12 Obesity-related traits; LIHC cis rs7572733 0.555 rs2341778 chr2:198776546 G/A cg10820045 chr2:198174542 NA -0.47 -7.2 -0.36 3.92e-12 Dermatomyositis; LIHC cis rs2576037 0.583 rs8094654 chr18:44527397 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.88 -0.3 9.84e-9 Personality dimensions; LIHC cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg19318889 chr4:1322082 MAEA -0.46 -6.41 -0.33 4.7e-10 Obesity-related traits; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg02635209 chr6:118822505 C6orf204;BRD7P3 -0.64 -6.85 -0.35 3.51e-11 Diastolic blood pressure; LIHC cis rs7845219 0.544 rs2945554 chr8:95939594 C/A cg16049864 chr8:95962084 TP53INP1 -0.43 -6.6 -0.34 1.58e-10 Type 2 diabetes; LIHC cis rs6748734 1.000 rs3936203 chr2:241834654 C/T cg08694578 chr2:241835147 C2orf54 0.5 6.89 0.35 2.76e-11 Urinary metabolites; LIHC cis rs2153535 0.580 rs4404802 chr6:8442052 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs12586317 0.547 rs13379372 chr14:35483882 A/C cg16230307 chr14:35515116 FAM177A1 0.79 13.35 0.59 5.37e-33 Psoriasis; LIHC cis rs6138458 1.000 rs227616 chr20:24908811 T/C cg26195577 chr20:24973756 C20orf3 1.1 13.84 0.6 6.94e-35 Blood protein levels; LIHC cis rs265548 0.646 rs36689 chr19:17910639 A/G cg04517722 chr19:17905589 B3GNT3 0.45 6.89 0.35 2.69e-11 Tumor biomarkers; LIHC cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg01411255 chr17:61851458 DDX42;CCDC47 -0.6 -9.93 -0.47 1.36e-20 Prudent dietary pattern; LIHC cis rs9733 0.791 rs11204693 chr1:150647987 C/T cg17724175 chr1:150552817 MCL1 -0.35 -7.32 -0.37 1.79e-12 Tonsillectomy; LIHC cis rs6840360 0.615 rs28659854 chr4:152607442 T/C cg22705602 chr4:152727874 NA -0.32 -6.85 -0.35 3.43e-11 Intelligence (multi-trait analysis); LIHC cis rs1113500 0.787 rs12047429 chr1:108633239 C/T cg06207961 chr1:108661230 NA 0.32 6.08 0.31 3.26e-9 Growth-regulated protein alpha levels; LIHC cis rs9733 0.596 rs11204704 chr1:150671630 T/C cg13175981 chr1:150552382 MCL1 -0.42 -5.91 -0.3 8.1e-9 Tonsillectomy; LIHC cis rs7027203 0.688 rs4075733 chr9:96624645 C/T cg13679303 chr9:96623674 NA -0.3 -6.73 -0.34 7.02e-11 DNA methylation (variation); LIHC cis rs1580019 0.534 rs13237495 chr7:32560687 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.09 0.31 3.12e-9 Cognitive ability; LIHC cis rs780096 0.506 rs780100 chr2:27652153 G/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg02993280 chr1:107599747 PRMT6 -0.69 -11.16 -0.52 6.98e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4822044 0.561 rs132781 chr22:42046122 T/G cg03806693 chr22:41940476 POLR3H 0.95 9.89 0.47 1.96e-20 Cannabis dependence symptom count; LIHC cis rs1552244 0.554 rs3846169 chr3:9997054 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.57 -8.32 -0.41 2.09e-15 Alzheimer's disease; LIHC cis rs919433 0.889 rs12693816 chr2:198208420 T/A cg10820045 chr2:198174542 NA -0.57 -9.24 -0.45 2.73e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17685 0.625 rs1639630 chr7:75730499 T/C cg16684958 chr7:75615977 POR 0.51 8.58 0.42 3.37e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs17253792 0.730 rs77079997 chr14:56155250 A/G cg01858014 chr14:56050164 KTN1 -0.69 -7.83 -0.39 6.12e-14 Putamen volume; LIHC trans rs61931739 0.534 rs11052986 chr12:34052578 T/C cg26384229 chr12:38710491 ALG10B 0.44 6.17 0.32 1.93e-9 Morning vs. evening chronotype; LIHC cis rs7726839 0.574 rs11739866 chr5:636299 C/T cg09021430 chr5:549028 NA -0.42 -8.46 -0.42 7.81e-16 Obesity-related traits; LIHC cis rs1443512 0.796 rs1822437 chr12:54340077 A/G cg12374095 chr12:54320830 NA -0.4 -5.82 -0.3 1.34e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs2303759 0.709 rs7256363 chr19:49827804 C/T cg22307029 chr19:49891270 CCDC155 0.56 8.62 0.42 2.52e-16 Multiple sclerosis; LIHC cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg09222892 chr1:25734099 RHCE -0.48 -8.9 -0.43 3.41e-17 Erythrocyte sedimentation rate; LIHC cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg26119090 chr2:26468346 HADHA;HADHB -1.1 -17.18 -0.68 3.93e-48 Gut microbiome composition (summer); LIHC cis rs7918232 0.698 rs6482586 chr10:27297829 A/C cg14442939 chr10:27389572 ANKRD26 0.59 5.96 0.31 6.44e-9 Breast cancer; LIHC cis rs11671005 0.568 rs55987239 chr19:59085045 G/A cg25952890 chr19:58913133 NA 0.68 6.93 0.35 2.15e-11 Mean platelet volume; LIHC cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg11905131 chr22:24372483 LOC391322 0.65 9.26 0.45 2.39e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8017423 0.967 rs61592400 chr14:90703252 T/C cg14092571 chr14:90743983 NA -0.36 -5.73 -0.3 2.26e-8 Mortality in heart failure; LIHC cis rs7927771 0.965 rs12787112 chr11:47687147 A/G cg20307385 chr11:47447363 PSMC3 -0.44 -5.74 -0.3 2.03e-8 Subjective well-being; LIHC cis rs12478296 0.591 rs6746311 chr2:243001279 A/G cg06360820 chr2:242988706 NA -0.74 -11.35 -0.52 1.52e-25 Obesity-related traits; LIHC cis rs3015497 0.626 rs7150204 chr14:51137355 T/C cg09863266 chr14:51125203 SAV1 -0.43 -6.77 -0.34 5.5e-11 Mean platelet volume; LIHC cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs4819052 0.851 rs1999334 chr21:46670457 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.47 6.73 0.34 7.16e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg00149659 chr3:10157352 C3orf10 0.68 6.98 0.35 1.59e-11 Alzheimer's disease; LIHC cis rs2576037 0.526 rs10853544 chr18:44474194 T/C cg19077165 chr18:44547161 KATNAL2 -0.44 -6.65 -0.34 1.15e-10 Personality dimensions; LIHC cis rs7927592 0.912 rs55767696 chr11:68375120 C/G cg16797656 chr11:68205561 LRP5 0.5 7.81 0.39 6.93e-14 Total body bone mineral density; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg00280220 chr17:61926910 NA 0.43 6.77 0.34 5.78e-11 Prudent dietary pattern; LIHC cis rs11190604 1.000 rs2489037 chr10:102319918 A/G cg07080220 chr10:102295463 HIF1AN -0.52 -7.1 -0.36 7.15e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg20887711 chr4:1340912 KIAA1530 0.65 10.87 0.51 7.85e-24 Obesity-related traits; LIHC cis rs1865760 0.929 rs9358896 chr6:25943197 C/A cg03517284 chr6:25882590 NA -0.43 -6.61 -0.34 1.48e-10 Height; LIHC cis rs3806843 0.735 rs2530242 chr5:140053351 G/C cg16179182 chr5:140090404 VTRNA1-1 0.36 5.85 0.3 1.16e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg05368731 chr17:41323189 NBR1 0.73 12.12 0.55 2.36e-28 Menopause (age at onset); LIHC cis rs875971 0.862 rs1643375 chr7:65872677 T/C cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs798554 0.797 rs35957220 chr7:2812632 C/G cg19346786 chr7:2764209 NA -0.46 -6.96 -0.35 1.74e-11 Height; LIHC cis rs611744 0.967 rs598022 chr8:109187759 C/T cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs950776 0.518 rs4886572 chr15:78837452 A/G cg22563815 chr15:78856949 CHRNA5 -0.37 -6.93 -0.35 2.08e-11 Sudden cardiac arrest; LIHC cis rs7312933 0.702 rs10785333 chr12:42586470 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.53 -7.69 -0.38 1.62e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6061231 0.761 rs2427312 chr20:60970591 C/T cg06026331 chr20:60912101 LAMA5 0.58 6.31 0.32 8.77e-10 Colorectal cancer; LIHC cis rs1577917 1.000 rs2166663 chr6:86593896 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.42 -7.98 -0.4 2.26e-14 Response to antipsychotic treatment; LIHC cis rs72772090 0.710 rs11745122 chr5:96060738 T/C cg17330273 chr5:96107758 CAST;ERAP1 -0.65 -7.2 -0.36 3.82e-12 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.35 0.32 6.9e-10 Schizophrenia; LIHC cis rs875971 1.000 rs709597 chr7:65825983 A/G cg11764359 chr7:65958608 NA -0.9 -16.9 -0.67 5.16e-47 Aortic root size; LIHC cis rs1215050 0.765 rs783925 chr4:98969881 T/C cg05340658 chr4:99064831 C4orf37 -0.4 -6.16 -0.32 2.04e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg00091569 chr3:40428383 ENTPD3 0.4 6.7 0.34 8.58e-11 Renal cell carcinoma; LIHC trans rs4332037 0.851 rs28728306 chr7:1961814 C/A cg11693508 chr17:37793320 STARD3 0.73 7.54 0.38 4.13e-13 Bipolar disorder; LIHC cis rs2806561 0.704 rs1757039 chr1:23508657 A/G cg12483005 chr1:23474871 LUZP1 0.46 7.33 0.37 1.66e-12 Height; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg22528358 chr1:107598549 PRMT6 -0.69 -11.15 -0.52 7.7e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.16 0.55 1.58e-28 Prudent dietary pattern; LIHC cis rs8038465 0.622 rs17185294 chr15:73858415 C/T cg15420318 chr15:73925796 NPTN -0.49 -7.33 -0.37 1.68e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg00149659 chr3:10157352 C3orf10 0.66 6.41 0.33 4.69e-10 Alzheimer's disease; LIHC cis rs9929218 0.953 rs3118227 chr16:68734855 G/A cg01231543 chr16:68741748 NA 0.38 5.79 0.3 1.59e-8 Colorectal cancer; LIHC cis rs6762 0.719 rs28620453 chr11:836971 G/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.79 -9.84 -0.47 2.77e-20 Mean platelet volume; LIHC cis rs7238033 0.624 rs7230298 chr18:43312519 A/G cg20610511 chr18:43302872 SLC14A1 -0.38 -6.32 -0.32 8e-10 Bladder cancer; LIHC trans rs12310956 0.532 rs11052933 chr12:33969881 G/A cg26384229 chr12:38710491 ALG10B 0.54 7.35 0.37 1.47e-12 Morning vs. evening chronotype; LIHC cis rs151997 0.962 rs27714 chr5:50180396 G/C cg06027927 chr5:50259733 NA 0.57 7.61 0.38 2.61e-13 Callous-unemotional behaviour; LIHC cis rs240764 0.746 rs239197 chr6:101133600 T/C cg09795085 chr6:101329169 ASCC3 0.52 7.1 0.36 7.39e-12 Neuroticism; LIHC cis rs17401966 1.000 rs4846210 chr1:10322153 A/G cg15208524 chr1:10270712 KIF1B 0.45 6.45 0.33 3.87e-10 Hepatocellular carcinoma; LIHC cis rs35110281 0.782 rs9981291 chr21:45031458 A/G cg21573476 chr21:45109991 RRP1B -0.57 -10.8 -0.5 1.42e-23 Mean corpuscular volume; LIHC cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg18306943 chr3:40428807 ENTPD3 0.42 7.24 0.36 2.98e-12 Renal cell carcinoma; LIHC trans rs7618501 0.669 rs7634084 chr3:49949834 A/T cg21659725 chr3:3221576 CRBN 0.68 10.89 0.51 6.5e-24 Intelligence (multi-trait analysis); LIHC cis rs9303280 0.806 rs11078928 chr17:38064469 T/C cg11212589 chr17:38028394 ZPBP2 0.35 7.13 0.36 6.05e-12 Self-reported allergy; LIHC cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC trans rs7613875 0.641 rs6446194 chr3:50067298 T/A cg21659725 chr3:3221576 CRBN -0.55 -8.2 -0.41 5.07e-15 Body mass index; LIHC cis rs6598955 0.670 rs10794525 chr1:26537193 C/A cg04990556 chr1:26633338 UBXN11 -0.56 -9.09 -0.44 8.38e-18 Obesity-related traits; LIHC cis rs17711722 0.583 rs11768292 chr7:65474801 G/T cg11764359 chr7:65958608 NA -0.7 -8.58 -0.42 3.42e-16 Calcium levels; LIHC cis rs3749237 0.595 rs4855839 chr3:49507847 G/A cg07636037 chr3:49044803 WDR6 0.53 8.08 0.4 1.1e-14 Resting heart rate; LIHC cis rs2576037 0.526 rs10853544 chr18:44474194 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.05 -0.36 9.86e-12 Personality dimensions; LIHC cis rs921968 0.643 rs3931102 chr2:219520405 C/T cg18887096 chr2:219472410 PLCD4 0.4 6.87 0.35 3.02e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg22029157 chr1:209979665 IRF6 0.51 8.16 0.4 6.56e-15 Cleft lip with or without cleft palate; LIHC cis rs2637266 0.935 rs1907299 chr10:78325316 T/C cg18941641 chr10:78392320 NA 0.29 5.96 0.31 6.34e-9 Pulmonary function; LIHC cis rs2439831 0.850 rs12702 chr15:44093927 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.47 -6.45 -0.33 3.82e-10 Lung cancer in ever smokers; LIHC cis rs1371867 0.846 rs1660349 chr8:101319326 G/A cg06636551 chr8:101224915 SPAG1 -0.49 -8.91 -0.43 3e-17 Atrioventricular conduction; LIHC cis rs4901869 0.864 rs12891575 chr14:59334342 T/A cg02291164 chr14:59296302 NA 0.47 5.89 0.3 9.11e-9 Panic disorder; LIHC cis rs763121 0.853 rs2413547 chr22:39107338 A/G cg14440974 chr22:39074834 NA -0.44 -7.14 -0.36 5.81e-12 Menopause (age at onset); LIHC cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg06481639 chr22:41940642 POLR3H -0.72 -6.74 -0.34 6.5500000000000006e-11 Vitiligo; LIHC cis rs3793683 1.000 rs3793683 chr10:134568387 G/T cg18305652 chr10:134549665 INPP5A -0.37 -5.96 -0.31 6.27e-9 Migraine; LIHC cis rs7917772 0.636 rs7897384 chr10:104529042 T/G cg22532475 chr10:104410764 TRIM8 0.36 6.54 0.33 2.29e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs66887589 0.934 rs7672519 chr4:120544112 C/T cg25214090 chr10:38739885 LOC399744 -0.39 -6.24 -0.32 1.27e-9 Diastolic blood pressure; LIHC cis rs3099143 1.000 rs3099137 chr15:77123626 G/A cg21673338 chr15:77095150 SCAPER -0.5 -7.65 -0.38 2.03e-13 Recalcitrant atopic dermatitis; LIHC cis rs763121 0.853 rs2413547 chr22:39107338 A/G cg06022373 chr22:39101656 GTPBP1 0.64 10.82 0.5 1.19e-23 Menopause (age at onset); LIHC cis rs7103648 0.864 rs71475909 chr11:47377283 A/G cg20307385 chr11:47447363 PSMC3 0.88 12.72 0.57 1.3e-30 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs2727020 0.734 rs1164664 chr11:49295542 T/G cg15704280 chr7:45808275 SEPT13 0.75 10.83 0.51 1.05e-23 Coronary artery disease; LIHC cis rs9467773 0.838 rs3734540 chr6:26463321 A/C cg09904177 chr6:26538194 HMGN4 0.49 9.08 0.44 9.12e-18 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.647 rs920712 chr15:77033934 G/A cg03037974 chr15:76606532 NA -0.61 -10.35 -0.49 5.23e-22 Blood metabolite levels; LIHC cis rs2070488 0.775 rs1132064 chr3:38566519 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.69 -11.34 -0.52 1.56e-25 Electrocardiographic conduction measures; LIHC cis rs7577696 0.554 rs35978916 chr2:32400635 T/C cg02381751 chr2:32503542 YIPF4 -0.47 -6.16 -0.32 2.08e-9 Inflammatory biomarkers; LIHC cis rs10876993 0.890 rs2640630 chr12:58067267 T/C cg18357645 chr12:58087776 OS9 0.52 8.54 0.42 4.56e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs1843834 0.505 rs7585047 chr2:225373897 C/T cg22509189 chr2:225307070 NA -0.82 -11.6 -0.53 1.82e-26 IgE levels in asthmatics (D.p. specific); LIHC cis rs6466055 0.720 rs12334245 chr7:104995627 T/C cg04380332 chr7:105027541 SRPK2 -0.37 -6.96 -0.35 1.77e-11 Schizophrenia; LIHC cis rs4319547 0.698 rs10744217 chr12:122942070 A/G cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.46 -0.37 7.03e-13 Body mass index; LIHC cis rs526231 0.853 rs35802 chr5:102607585 A/T cg05225461 chr5:102596755 C5orf30 0.37 5.75 0.3 1.98e-8 Primary biliary cholangitis; LIHC cis rs9473924 0.542 rs4294001 chr6:50850065 G/A cg14470998 chr6:50812995 TFAP2B 0.91 10.53 0.49 1.22e-22 Body mass index; LIHC cis rs4948275 0.530 rs2393853 chr10:63167688 C/G cg03237606 chr10:63212265 TMEM26 0.32 7.19 0.36 4.17e-12 Night sleep phenotypes; LIHC cis rs6545883 0.929 rs55806663 chr2:61740487 G/T cg14146966 chr2:61757674 XPO1 0.48 8.46 0.42 7.83e-16 Tuberculosis; LIHC cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg23758822 chr17:41437982 NA 0.94 17.84 0.69 8.48e-51 Menopause (age at onset); LIHC cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg21782813 chr7:2030301 MAD1L1 0.42 7.14 0.36 5.6e-12 Schizophrenia; LIHC cis rs317689 0.819 rs317683 chr12:69713630 T/G cg19645103 chr12:69753606 YEATS4 -0.47 -6.37 -0.33 6.19e-10 Response to diuretic therapy; LIHC cis rs2228479 0.681 rs10153055 chr16:89965842 C/T cg03721293 chr16:90014378 DEF8 0.35 5.71 0.3 2.42e-8 Skin colour saturation; LIHC cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg00656387 chr3:40428638 ENTPD3 0.42 7.03 0.36 1.15e-11 Renal cell carcinoma; LIHC cis rs12701220 0.604 rs12702122 chr7:1149494 C/G cg09177884 chr7:1199841 ZFAND2A -0.5 -5.83 -0.3 1.25e-8 Bronchopulmonary dysplasia; LIHC cis rs9858542 1.000 rs9858542 chr3:49701983 A/G cg03060546 chr3:49711283 APEH 0.61 8.15 0.4 6.97e-15 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs10792665 0.649 rs7116356 chr11:82769922 T/C cg24227371 chr11:82718527 RAB30 -0.37 -8.78 -0.43 7.83e-17 Obesity-related traits; LIHC cis rs8103278 1.000 rs7256192 chr19:46338492 G/A cg14061069 chr19:46274453 DMPK -0.55 -8.49 -0.42 6.38e-16 Coronary artery disease; LIHC cis rs5167 0.504 rs4803781 chr19:45459671 C/T cg09555818 chr19:45449301 APOC2 0.19 5.79 0.3 1.56e-8 Blood protein levels; LIHC cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg19318889 chr4:1322082 MAEA 0.64 10.39 0.49 3.59e-22 Longevity; LIHC cis rs1031391 0.716 rs10772416 chr12:11170087 T/A cg25677688 chr12:11176386 TAS2R19;PRR4;PRH1 0.77 7.63 0.38 2.4e-13 Bitter taste perception; LIHC cis rs11098699 0.821 rs13148385 chr4:124206117 A/G cg09941581 chr4:124220074 SPATA5 0.32 6.38 0.33 5.62e-10 Mosquito bite size; LIHC cis rs7520050 0.931 rs7526678 chr1:46374159 A/G cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.92 0.3 7.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs17376456 0.569 rs896729 chr5:93222178 A/G cg25358565 chr5:93447407 FAM172A -0.78 -7.58 -0.38 3.18e-13 Diabetic retinopathy; LIHC cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg11890956 chr21:40555474 PSMG1 -0.5 -8.16 -0.4 6.57e-15 Cognitive function; LIHC cis rs7617773 0.817 rs11130163 chr3:48312658 T/C cg11946769 chr3:48343235 NME6 0.64 8.81 0.43 6.36e-17 Coronary artery disease; LIHC cis rs2303759 0.676 rs10426452 chr19:49907690 G/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.86 0.43 4.41e-17 Multiple sclerosis; LIHC cis rs1843834 0.539 rs1494109 chr2:225441833 G/A cg12698349 chr2:225449008 CUL3 0.68 10.34 0.49 5.33e-22 IgE levels in asthmatics (D.p. specific); LIHC cis rs3096299 0.967 rs28575874 chr16:89469890 C/T cg01788221 chr16:89496183 ANKRD11 -0.39 -6.08 -0.31 3.26e-9 Multiple myeloma (IgH translocation); LIHC cis rs9457247 0.602 rs6456152 chr6:167472062 A/G cg23791538 chr6:167370224 RNASET2 -0.52 -7.84 -0.39 5.63e-14 Crohn's disease; LIHC cis rs7607369 0.714 rs4674334 chr2:219622811 T/C cg02985541 chr2:219472218 PLCD4 -0.38 -5.91 -0.3 8.4e-9 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs694739 0.628 rs508168 chr11:64135435 G/A cg23796481 chr11:64053134 BAD;GPR137 0.46 6.22 0.32 1.42e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs919433 0.617 rs34632716 chr2:198542619 C/T cg10820045 chr2:198174542 NA -0.5 -7.62 -0.38 2.48e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg25897951 chr4:1244024 CTBP1;C4orf42 -0.4 -5.71 -0.3 2.45e-8 Longevity; LIHC cis rs951366 0.789 rs864783 chr1:205711974 T/C cg14159672 chr1:205819179 PM20D1 0.73 10.31 0.49 7.04e-22 Menarche (age at onset); LIHC cis rs1475911 0.708 rs56109792 chr21:43520060 A/G cg24372256 chr21:43528868 UMODL1;C21orf128 -0.35 -5.8 -0.3 1.53e-8 IgG glycosylation; LIHC cis rs506338 0.517 rs530252 chr11:64443465 T/C cg03263716 chr11:64435066 NRXN2 0.35 7.57 0.38 3.46e-13 Body mass index;Urate levels; LIHC cis rs4654899 0.758 rs6697284 chr1:21295599 G/A cg08539965 chr1:21396338 EIF4G3 0.34 6.15 0.32 2.16e-9 Superior frontal gyrus grey matter volume; LIHC cis rs68092024 0.731 rs793480 chr3:99488364 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.91 0.3 8.09e-9 Cleft lip with or without cleft palate; LIHC cis rs10911232 0.524 rs4487994 chr1:182982173 T/A ch.1.3577855R chr1:183094577 LAMC1 0.58 9.99 0.48 8.54e-21 Hypertriglyceridemia; LIHC cis rs7833790 0.724 rs6473310 chr8:82707981 A/G cg27398817 chr8:82754497 SNX16 -0.36 -6.79 -0.34 4.94e-11 Diastolic blood pressure; LIHC cis rs4319547 1.000 rs1392236 chr12:123074890 C/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.19 -0.36 4.22e-12 Body mass index; LIHC cis rs2228479 0.850 rs17226519 chr16:89839854 T/C cg06558623 chr16:89946397 TCF25 0.84 11.66 0.53 1.09e-26 Skin colour saturation; LIHC cis rs9318086 0.712 rs9318099 chr13:24442462 C/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.57 -11.32 -0.52 1.84e-25 Myopia (pathological); LIHC cis rs2642442 1.000 rs867772 chr1:220972343 A/G cg04704887 chr1:220970030 MOSC1 -0.45 -5.79 -0.3 1.6e-8 Cholesterol, total;LDL cholesterol; LIHC cis rs12701220 0.655 rs12702117 chr7:1148702 T/C cg16145915 chr7:1198662 ZFAND2A -0.34 -6.79 -0.34 5.02e-11 Bronchopulmonary dysplasia; LIHC cis rs903552 0.800 rs28470883 chr15:102000824 G/A cg00659931 chr15:102010125 PCSK6 -0.44 -5.84 -0.3 1.19e-8 Diabetic kidney disease; LIHC cis rs4906332 0.782 rs12891288 chr14:103999750 C/T cg04998671 chr14:104000505 TRMT61A -0.57 -7.51 -0.38 5.1e-13 Coronary artery disease; LIHC cis rs7100689 0.577 rs1143694 chr10:82040052 C/T cg01528321 chr10:82214614 TSPAN14 -0.87 -11.84 -0.54 2.45e-27 Post bronchodilator FEV1; LIHC cis rs9309473 1.000 rs7558944 chr2:73810909 T/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.5 -0.33 2.86e-10 Metabolite levels; LIHC trans rs3960554 0.808 rs867973 chr7:75686007 G/A cg19862616 chr7:65841803 NCRNA00174 0.6 8.3 0.41 2.4e-15 Eotaxin levels; LIHC cis rs1982963 1.000 rs753051 chr14:52505360 A/G cg10843707 chr14:52510701 NID2 -0.44 -7.7 -0.38 1.51e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs16828019 0.852 rs34386859 chr1:41564024 C/T cg03387723 chr1:41708464 SCMH1 -0.42 -6.82 -0.35 4.11e-11 Intelligence (multi-trait analysis); LIHC cis rs7903847 0.642 rs11189174 chr10:99139600 C/G cg06359132 chr10:99160096 RRP12 -0.42 -6.43 -0.33 4.2e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs362296 0.698 rs3095080 chr4:3264418 C/T cg06533319 chr4:3265114 C4orf44 0.35 6.72 0.34 7.81e-11 Parental longevity (mother's age at death); LIHC cis rs1005277 0.579 rs2023351 chr10:38378814 A/G cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs35306767 0.715 rs17293580 chr10:1034895 T/C cg20503657 chr10:835505 NA 0.79 7.25 0.36 2.82e-12 Eosinophil percentage of granulocytes; LIHC cis rs644799 0.965 rs687529 chr11:95545587 T/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.52e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9399137 0.507 rs4896128 chr6:135349756 A/G cg24558204 chr6:135376177 HBS1L -0.62 -10.81 -0.5 1.25e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC trans rs9500256 1.000 rs9500256 chr6:58308955 C/T cg03371099 chr6:57305889 PRIM2 -0.37 -6.41 -0.33 4.94e-10 Eosinophilic esophagitis (pediatric); LIHC cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg20295408 chr7:1910781 MAD1L1 0.42 5.92 0.3 7.86e-9 Bipolar disorder and schizophrenia; LIHC trans rs11098499 0.754 rs1511017 chr4:120250805 G/A cg25214090 chr10:38739885 LOC399744 0.51 8.29 0.41 2.61e-15 Corneal astigmatism; LIHC cis rs2180341 1.000 rs6910763 chr6:127630925 T/C cg24812749 chr6:127587940 RNF146 1.07 16.09 0.66 9.4e-44 Breast cancer; LIHC cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg18252515 chr7:66147081 NA -1.24 -16.13 -0.66 6.34e-44 Diabetic kidney disease; LIHC cis rs9916302 0.904 rs587343 chr17:37440603 C/T cg07936489 chr17:37558343 FBXL20 0.81 12.98 0.57 1.36e-31 Glomerular filtration rate (creatinine); LIHC cis rs7552404 0.883 rs77773255 chr1:76217193 G/A cg10523679 chr1:76189770 ACADM 0.63 8.78 0.43 7.88e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs986417 1.000 rs1313243 chr14:60876398 C/T cg27398547 chr14:60952738 C14orf39 -0.74 -8.61 -0.42 2.67e-16 Gut microbiota (bacterial taxa); LIHC trans rs7395662 0.517 rs10838960 chr11:48584741 A/G cg15704280 chr7:45808275 SEPT13 -0.47 -7.02 -0.35 1.2e-11 HDL cholesterol; LIHC cis rs2032447 0.639 rs198810 chr6:26128618 A/G cg18357526 chr6:26021779 HIST1H4A -0.87 -12.64 -0.56 2.5e-30 Intelligence (multi-trait analysis); LIHC cis rs7095607 0.606 rs4746735 chr10:69950502 A/C cg18986048 chr10:69913749 MYPN -0.4 -5.96 -0.31 6.35e-9 Lung function (FVC); LIHC cis rs6963495 0.519 rs3892297 chr7:105152173 G/A cg19920283 chr7:105172520 RINT1 0.67 6.19 0.32 1.75e-9 Bipolar disorder (body mass index interaction); LIHC trans rs10838798 0.523 rs4752917 chr11:48241639 A/G cg15704280 chr7:45808275 SEPT13 -0.41 -6.16 -0.32 2.08e-9 Height; LIHC cis rs3824867 0.920 rs9734013 chr11:47451517 G/T cg20307385 chr11:47447363 PSMC3 -0.58 -7.89 -0.39 4.24e-14 Mean corpuscular hemoglobin; LIHC cis rs67311347 0.668 rs73071710 chr3:40288587 A/G cg13409248 chr3:40428643 ENTPD3 0.45 7.28 0.37 2.25e-12 Renal cell carcinoma; LIHC cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg21782813 chr7:2030301 MAD1L1 0.41 7.1 0.36 7.27e-12 Bipolar disorder and schizophrenia; LIHC cis rs3008870 1.000 rs3008856 chr1:67387901 T/C cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.25e-8 Lymphocyte percentage of white cells; LIHC cis rs7647973 1.000 rs6805609 chr3:49471522 C/G cg07636037 chr3:49044803 WDR6 -0.55 -6.61 -0.34 1.44e-10 Menarche (age at onset); LIHC cis rs910316 0.967 rs175502 chr14:75533679 A/G cg11812906 chr14:75593930 NEK9 -0.76 -15.24 -0.64 2.1e-40 Height; LIHC cis rs13108904 0.775 rs2279282 chr4:1216033 G/C cg20887711 chr4:1340912 KIAA1530 0.46 6.37 0.33 6.1e-10 Obesity-related traits; LIHC cis rs860295 0.812 rs12081192 chr1:155738044 A/G cg02153340 chr1:155202674 NA -0.35 -6.46 -0.33 3.5e-10 Body mass index; LIHC cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg27170947 chr2:26402098 FAM59B 0.71 8.56 0.42 3.96e-16 Gut microbiome composition (summer); LIHC cis rs6582630 0.555 rs10785443 chr12:38463792 A/C cg26384229 chr12:38710491 ALG10B 0.64 8.84 0.43 4.99e-17 Drug-induced liver injury (flucloxacillin); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21806233 chr11:111956119 TIMM8B;SDHD 0.48 6.08 0.31 3.25e-9 Systolic blood pressure; LIHC cis rs7927592 0.913 rs67605986 chr11:68300955 C/T cg01657329 chr11:68192670 LRP5 -0.47 -6.08 -0.31 3.22e-9 Total body bone mineral density; LIHC cis rs60871478 1.000 rs62432861 chr7:807649 G/A cg04727924 chr7:799746 HEATR2 -0.58 -8.6 -0.42 2.86e-16 Cerebrospinal P-tau181p levels; LIHC cis rs6089584 0.854 rs6061985 chr20:60622362 T/C cg13770153 chr20:60521292 NA -0.33 -6.59 -0.34 1.68e-10 Body mass index; LIHC cis rs61542988 0.756 rs5013587 chr7:22882660 C/T cg11367502 chr7:22862612 TOMM7 0.56 9.75 0.47 5.79e-20 Fibrinogen levels; LIHC cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg04267008 chr7:1944627 MAD1L1 -0.63 -10.1 -0.48 3.62e-21 Bipolar disorder and schizophrenia; LIHC trans rs61931739 0.500 rs7306334 chr12:34482900 A/G cg26384229 chr12:38710491 ALG10B -0.79 -9.79 -0.47 4.14e-20 Morning vs. evening chronotype; LIHC trans rs11098499 0.739 rs6534130 chr4:120131339 A/T cg25214090 chr10:38739885 LOC399744 -0.38 -6.25 -0.32 1.22e-9 Corneal astigmatism; LIHC cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg06634786 chr22:41940651 POLR3H -0.65 -7.24 -0.36 3.03e-12 Vitiligo; LIHC trans rs7618501 0.966 rs2352974 chr3:49890613 C/T cg21582582 chr3:182698605 DCUN1D1 0.53 6.97 0.35 1.63e-11 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03965827 chr15:50979356 TRPM7 0.41 6.28 0.32 1.05e-9 Cognitive function; LIHC cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg01339444 chr6:118972232 C6orf204 0.58 5.74 0.3 2.07e-8 Diastolic blood pressure; LIHC cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg22528358 chr1:107598549 PRMT6 0.72 11.84 0.54 2.44e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs35160687 0.712 rs1863057 chr2:86502101 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 0.36 5.79 0.3 1.6e-8 Night sleep phenotypes; LIHC cis rs7520050 0.966 rs1085244 chr1:46563680 C/A cg03146154 chr1:46216737 IPP -0.38 -6.25 -0.32 1.22e-9 Red blood cell count;Reticulocyte count; LIHC cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg11987759 chr7:65425863 GUSB -0.39 -6.15 -0.32 2.22e-9 Aortic root size; LIHC cis rs804280 0.565 rs1466785 chr8:11623456 C/T cg11123440 chr8:11619852 NA 0.32 6.13 0.31 2.43e-9 Myopia (pathological); LIHC cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg10802521 chr3:52805072 NEK4 -0.45 -7.4 -0.37 1.07e-12 Bipolar disorder; LIHC cis rs10911232 0.507 rs4652767 chr1:183002483 G/C ch.1.3577855R chr1:183094577 LAMC1 0.6 10.27 0.49 9.23e-22 Hypertriglyceridemia; LIHC cis rs10911251 0.546 rs2147578 chr1:183107699 G/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.55 0.5 9.94e-23 Colorectal cancer; LIHC cis rs748404 0.631 rs2412781 chr15:43667900 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.54 -9.68 -0.46 9.78e-20 Lung cancer; LIHC cis rs1419980 0.673 rs12146828 chr12:7739341 C/G cg25828445 chr12:7781288 NA -0.41 -6.28 -0.32 1.03e-9 HDL cholesterol levels; LIHC cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg11494091 chr17:61959527 GH2 0.44 8.09 0.4 1.08e-14 Prudent dietary pattern; LIHC trans rs9641123 0.639 rs7803666 chr7:93200058 A/G cg09745688 chr16:2908918 PRSS22 -0.36 -6.15 -0.32 2.2e-9 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg04025307 chr7:1156635 C7orf50 0.6 10.44 0.49 2.39e-22 Longevity;Endometriosis; LIHC cis rs4631830 0.720 rs11004422 chr10:51498336 A/G cg16070123 chr10:51489643 NA 0.37 5.9 0.3 8.68e-9 Prostate-specific antigen levels; LIHC cis rs2576037 0.583 rs616900 chr18:44410849 T/A cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.82 -0.3 1.34e-8 Personality dimensions; LIHC cis rs11148252 0.740 rs9536046 chr13:52955899 T/G cg00495681 chr13:53174319 NA 0.37 5.92 0.3 7.76e-9 Lewy body disease; LIHC cis rs9549328 0.800 rs9549617 chr13:113628070 C/A cg08890338 chr13:113700818 MCF2L -0.35 -5.74 -0.3 2.13e-8 Systolic blood pressure; LIHC cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg13047869 chr3:10149882 C3orf24 0.48 5.78 0.3 1.64e-8 Alzheimer's disease; LIHC cis rs921968 0.591 rs13421421 chr2:219519286 A/G cg02985541 chr2:219472218 PLCD4 0.43 7.93 0.39 3.15e-14 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg00166722 chr3:10149974 C3orf24 0.52 6.02 0.31 4.54e-9 Alzheimer's disease; LIHC cis rs12291225 0.679 rs11605531 chr11:14291594 A/G cg05501817 chr11:14380813 RRAS2 -0.42 -5.74 -0.3 2.09e-8 Sense of smell; LIHC cis rs7914558 0.966 rs10786727 chr10:104698523 G/A cg15744005 chr10:104629667 AS3MT -0.4 -9.11 -0.44 7e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs68170813 0.523 rs11766131 chr7:107071138 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.74 -0.3 2.1e-8 Coronary artery disease; LIHC cis rs763121 0.853 rs5757181 chr22:39013522 G/A cg14440974 chr22:39074834 NA -0.44 -6.95 -0.35 1.83e-11 Menopause (age at onset); LIHC cis rs600806 0.850 rs3768493 chr1:109935505 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.11 -0.31 2.77e-9 Intelligence (multi-trait analysis); LIHC cis rs4665809 1.000 rs6546736 chr2:26293878 C/T cg04944784 chr2:26401820 FAM59B 0.67 8.45 0.42 8.78e-16 Gut microbiome composition (summer); LIHC cis rs8180040 1.000 rs7613282 chr3:47389409 C/T cg16586182 chr3:47516702 SCAP 0.58 10.66 0.5 4.27e-23 Colorectal cancer; LIHC cis rs4294134 0.832 rs12530805 chr7:135278791 C/T cg20392616 chr7:135392013 SLC13A4 0.38 6.03 0.31 4.31e-9 Paget's disease; LIHC cis rs367615 0.552 rs3828603 chr5:108712068 G/C cg17395555 chr5:108820864 NA -0.29 -6.33 -0.32 7.57e-10 Colorectal cancer (SNP x SNP interaction); LIHC cis rs2404602 0.735 rs2436994 chr15:76801063 G/C cg23625390 chr15:77176239 SCAPER -0.48 -8.04 -0.4 1.46e-14 Blood metabolite levels; LIHC cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg11062466 chr8:58055876 NA 0.39 5.73 0.3 2.2e-8 Developmental language disorder (linguistic errors); LIHC cis rs9918079 0.560 rs12651550 chr4:15641018 G/C cg16509355 chr4:15471240 CC2D2A -0.46 -7.12 -0.36 6.56e-12 Obesity-related traits; LIHC cis rs12701220 0.817 rs1058729 chr7:1087283 C/T cg18765753 chr7:1198926 ZFAND2A -0.41 -5.89 -0.3 9.33e-9 Bronchopulmonary dysplasia; LIHC cis rs6545883 1.000 rs778758 chr2:61782161 T/C cg15711740 chr2:61764176 XPO1 -0.42 -5.74 -0.3 2.05e-8 Tuberculosis; LIHC cis rs600806 0.778 rs4970767 chr1:110015183 G/A cg02415029 chr1:110025642 ATXN7L2 -0.44 -5.75 -0.3 1.95e-8 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg11062466 chr8:58055876 NA 0.51 7.5 0.38 5.63e-13 Developmental language disorder (linguistic errors); LIHC cis rs1348850 0.750 rs12997716 chr2:178494629 G/A cg02961200 chr2:178257176 LOC100130691;AGPS 0.6 7.86 0.39 4.96e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10791097 0.967 rs10791099 chr11:130718813 G/C cg12179176 chr11:130786555 SNX19 0.62 9.6 0.46 1.79e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23092576 chr1:21672253 ECE1 0.43 6.15 0.32 2.16e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9649465 1.000 rs10238422 chr7:123353708 G/C cg03229431 chr7:123269106 ASB15 -0.36 -7.8 -0.39 7.74e-14 Migraine; LIHC cis rs7487075 0.930 rs11183468 chr12:46806261 A/T cg11331445 chr12:47219877 SLC38A4 0.28 5.89 0.3 9.36e-9 Itch intensity from mosquito bite; LIHC cis rs6598955 0.640 rs1577507 chr1:26547179 C/T cg00852783 chr1:26633632 UBXN11 0.48 8.15 0.4 6.91e-15 Obesity-related traits; LIHC cis rs1144333 0.655 rs17097695 chr1:76387258 A/C cg22875332 chr1:76189707 ACADM 0.42 6.24 0.32 1.31e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs4638749 0.677 rs7568919 chr2:108832376 C/A cg06795125 chr2:108905320 SULT1C2 -0.3 -6.01 -0.31 4.69e-9 Blood pressure; LIHC cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg08888203 chr3:10149979 C3orf24 0.6 6.73 0.34 7.11e-11 Alzheimer's disease; LIHC cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs6882046 0.513 rs42850 chr5:88019474 G/A cg22951263 chr5:87985283 NA -0.39 -6.72 -0.34 7.43e-11 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; LIHC cis rs2760061 0.819 rs708114 chr1:228197496 G/A cg02753203 chr1:228287806 NA 0.48 7.97 0.4 2.43e-14 Diastolic blood pressure; LIHC cis rs7927592 1.000 rs7927592 chr11:68369960 G/A cg01657329 chr11:68192670 LRP5 -0.48 -6.34 -0.32 7.26e-10 Total body bone mineral density; LIHC cis rs812925 0.519 rs967968 chr2:61656056 C/G cg14146966 chr2:61757674 XPO1 -0.38 -6.2 -0.32 1.62e-9 Immature fraction of reticulocytes; LIHC trans rs11098499 0.954 rs56270433 chr4:120406030 C/T cg25214090 chr10:38739885 LOC399744 0.58 9.5 0.46 3.69e-19 Corneal astigmatism; LIHC cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.54e-26 Alzheimer's disease; LIHC cis rs1552244 0.882 rs13064570 chr3:9997545 G/C cg08888203 chr3:10149979 C3orf24 0.46 5.83 0.3 1.28e-8 Alzheimer's disease; LIHC trans rs800082 0.668 rs9856190 chr3:144288547 G/C cg24215973 chr2:240111563 HDAC4 -0.57 -8.59 -0.42 3.08e-16 Smoking behavior; LIHC cis rs1005277 0.579 rs1740749 chr10:38521646 A/G cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs6964587 1.000 rs7802788 chr7:91736874 A/G cg17063962 chr7:91808500 NA 1.04 20.83 0.75 8.28e-63 Breast cancer; LIHC cis rs9811920 0.598 rs793470 chr3:99548274 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.49 -6.94 -0.35 1.95e-11 Axial length; LIHC cis rs11650776 1 rs11650776 chr17:37641402 G/A cg07936489 chr17:37558343 FBXL20 -0.85 -13.6 -0.59 5.58e-34 Lung function (FEV1); LIHC cis rs6582630 0.502 rs10880092 chr12:38262965 A/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs3793683 0.965 rs3829131 chr10:134564627 A/G cg26818010 chr10:134567672 INPP5A 0.63 8.4 0.41 1.17e-15 Migraine; LIHC cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg27286337 chr10:134555280 INPP5A 0.92 12.86 0.57 3.71e-31 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs6489882 0.703 rs10774671 chr12:113357193 G/A cg10175203 chr3:128143634 NA 0.37 6.12 0.31 2.5e-9 Chronic lymphocytic leukemia; LIHC cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.22 0.52 4.31e-25 Colorectal cancer; LIHC cis rs3806843 1.000 rs1030164 chr5:140185272 A/G cg26395211 chr5:140044315 WDR55 -0.42 -6.2 -0.32 1.66e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs470119 1.000 rs470119 chr22:50966914 C/T cg12969734 chr22:50962224 SCO2 -0.49 -7.85 -0.39 5.37e-14 Mean corpuscular hemoglobin; LIHC cis rs2072438 0.503 rs10739590 chr9:123871481 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.45 6.27 0.32 1.11e-9 Rheumatoid arthritis; LIHC cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg23758822 chr17:41437982 NA 0.94 17.94 0.7 3.44e-51 Menopause (age at onset); LIHC cis rs9910055 0.529 rs228766 chr17:42186813 A/G cg19774624 chr17:42201019 HDAC5 0.5 6.25 0.32 1.23e-9 Total body bone mineral density; LIHC cis rs6754311 0.731 rs12988076 chr2:136569848 C/A cg17750252 chr2:136567154 LCT 0.35 6.31 0.32 8.53e-10 Mosquito bite size; LIHC cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg07677032 chr17:61819896 STRADA 0.44 6.32 0.32 8.32e-10 Prudent dietary pattern; LIHC cis rs4819052 0.808 rs11909411 chr21:46676556 A/C cg22633049 chr21:46681294 NA -0.36 -6.13 -0.31 2.47e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6546550 0.901 rs6725425 chr2:70150674 T/C cg02498382 chr2:70120550 SNRNP27 -0.44 -7.62 -0.38 2.56e-13 Prevalent atrial fibrillation; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg17774058 chr20:6748719 BMP2 0.46 6.98 0.35 1.55e-11 Cognitive function; LIHC cis rs17001868 0.568 rs9611312 chr22:40734790 T/C cg07138101 chr22:40742427 ADSL 0.55 6.56 0.33 1.94e-10 Mammographic density (dense area); LIHC cis rs911119 1.000 rs34374560 chr20:23609462 C/T cg16589663 chr20:23618590 CST3 0.74 7.52 0.38 4.79e-13 Chronic kidney disease; LIHC cis rs317689 0.513 rs529268 chr12:69687051 G/A cg22834771 chr12:69754056 YEATS4 -0.4 -6.46 -0.33 3.53e-10 Response to diuretic therapy; LIHC cis rs3008870 0.959 rs4655658 chr1:67389608 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.46 0.66 3.08e-45 Lymphocyte percentage of white cells; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14077270 chr15:45879818 PLDN -0.48 -6.4 -0.33 5.15e-10 Systolic blood pressure; LIHC cis rs782590 0.837 rs809732 chr2:55914621 T/C cg03859395 chr2:55845619 SMEK2 0.82 14.01 0.6 1.51e-35 Metabolic syndrome; LIHC cis rs4979906 1.000 rs4979908 chr10:79452127 C/T cg07817648 chr10:79422355 NA -0.28 -6.08 -0.31 3.16e-9 Mortality in heart failure; LIHC cis rs7528419 1.000 rs646776 chr1:109818530 C/T cg00908766 chr1:109817496 CELSR2 0.5 9.0 0.44 1.56e-17 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg00280220 chr17:61926910 NA 0.44 7.07 0.36 8.7e-12 Prudent dietary pattern; LIHC cis rs13401104 0.796 rs1921661 chr2:237121441 T/A cg19324714 chr2:237145437 ASB18 0.37 5.87 0.3 1.03e-8 Educational attainment; LIHC cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg24549020 chr5:56110836 MAP3K1 0.51 6.48 0.33 3.22e-10 Initial pursuit acceleration; LIHC cis rs11630290 0.592 rs11071767 chr15:64154635 A/G cg12036633 chr15:63758958 NA -0.65 -6.94 -0.35 1.99e-11 Iris characteristics; LIHC cis rs11893307 0.599 rs11900857 chr2:191659011 T/C cg05765582 chr2:191677683 NA 0.32 5.75 0.3 2e-8 Mean platelet volume; LIHC cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg27572855 chr1:25598939 RHD 0.4 8.62 0.42 2.57e-16 Erythrocyte sedimentation rate; LIHC cis rs2153535 0.541 rs5026687 chr6:8473957 A/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.15e-16 Motion sickness; LIHC cis rs7572733 0.515 rs6724526 chr2:198858401 A/G cg00792783 chr2:198669748 PLCL1 0.45 6.56 0.33 2.04e-10 Dermatomyositis; LIHC cis rs17253792 0.822 rs17683614 chr14:56041058 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.62 -0.34 1.43e-10 Putamen volume; LIHC cis rs2439831 1.000 rs689826 chr15:43749916 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.61 8.59 0.42 3.07e-16 Lung cancer in ever smokers; LIHC cis rs1348850 0.537 rs3770010 chr2:178537796 T/C cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.26 0.41 3.19e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs507080 0.883 rs563549 chr11:118558953 G/A cg04173919 chr11:118528438 PHLDB1 0.35 6.56 0.33 2.01e-10 Serum metabolite levels; LIHC cis rs3806843 0.838 rs2337514 chr5:140132732 T/C cg26395211 chr5:140044315 WDR55 0.39 5.88 0.3 9.83e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs911119 1.000 rs6114206 chr20:23611789 A/G cg16589663 chr20:23618590 CST3 0.74 7.75 0.39 1.09e-13 Chronic kidney disease; LIHC cis rs17496827 0.727 rs7581707 chr2:223360730 C/T cg25565276 chr2:223520875 FARSB 0.41 6.08 0.31 3.13e-9 Anorexia nervosa; LIHC cis rs7100689 0.646 rs1953972 chr10:82145666 A/G cg00277334 chr10:82204260 NA -0.58 -7.53 -0.38 4.6e-13 Post bronchodilator FEV1; LIHC cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg11062466 chr8:58055876 NA 0.52 7.52 0.38 4.86e-13 Developmental language disorder (linguistic errors); LIHC cis rs10256972 1.000 rs10256972 chr7:1039003 G/T cg07308232 chr7:1071921 C7orf50 0.49 8.3 0.41 2.44e-15 Longevity;Endometriosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg19030620 chr1:220922217 MOSC2 0.34 6.94 0.35 2e-11 Cognitive function; LIHC cis rs727505 1.000 rs10265763 chr7:124451514 G/A cg23710748 chr7:124431027 NA -0.34 -5.95 -0.31 6.5e-9 Lewy body disease; LIHC cis rs6912958 0.712 rs4707383 chr6:88330602 T/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.93 -0.39 3.13e-14 Monocyte percentage of white cells; LIHC cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg18252515 chr7:66147081 NA -1.3 -17.11 -0.68 7.3e-48 Diabetic kidney disease; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg09455208 chr3:40491958 NA -0.39 -7.8 -0.39 7.81e-14 Renal cell carcinoma; LIHC cis rs34779708 0.931 rs34954932 chr10:35410807 G/T cg04310649 chr10:35416472 CREM -0.44 -6.0 -0.31 5.07e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs78545713 0.649 rs79308455 chr6:26224377 A/G cg16070018 chr6:26224392 HIST1H3E 0.67 6.53 0.33 2.4e-10 Iron status biomarkers (total iron binding capacity); LIHC cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg19318889 chr4:1322082 MAEA 0.41 5.91 0.3 8.37e-9 Obesity-related traits; LIHC cis rs12451471 0.559 rs1042396 chr17:78084769 G/A cg06718696 chr17:78121285 EIF4A3 0.95 11.13 0.52 8.94e-25 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs36051895 0.622 rs13440043 chr9:5268264 A/G cg02405213 chr9:5042618 JAK2 -0.61 -9.28 -0.45 2.02e-18 Pediatric autoimmune diseases; LIHC cis rs7572733 0.534 rs696817 chr2:198722225 A/G cg00792783 chr2:198669748 PLCL1 0.47 6.89 0.35 2.77e-11 Dermatomyositis; LIHC cis rs12971120 0.891 rs12608037 chr18:72169395 A/G cg26446133 chr18:72167187 CNDP2 -0.81 -14.86 -0.63 6.73e-39 Refractive error; LIHC cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg14967899 chr8:26434689 DPYSL2 0.45 6.35 0.32 6.77e-10 Migraine with aura; LIHC cis rs892961 0.932 rs7224116 chr17:75413177 A/G cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs11673344 0.764 rs1644645 chr19:37463430 G/A cg27390819 chr19:37464633 NA -0.53 -6.29 -0.32 9.74e-10 Obesity-related traits; LIHC cis rs1448094 0.512 rs1349063 chr12:86264237 C/T cg02569458 chr12:86230093 RASSF9 0.46 6.21 0.32 1.56e-9 Major depressive disorder; LIHC cis rs7666738 0.830 rs921523 chr4:98841659 C/T cg05340658 chr4:99064831 C4orf37 0.66 11.81 0.54 3.06e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs1035144 0.505 rs10145099 chr14:81456694 C/T cg06600135 chr14:81408086 NA -0.42 -7.36 -0.37 1.38e-12 Male sexual orientation; LIHC cis rs17818399 0.547 rs12997164 chr2:46758746 A/C cg02822958 chr2:46747628 ATP6V1E2 0.42 6.19 0.32 1.72e-9 Height; LIHC cis rs4474465 0.850 rs4945294 chr11:78256864 G/A cg27205649 chr11:78285834 NARS2 0.37 5.72 0.3 2.31e-8 Alzheimer's disease (survival time); LIHC trans rs6489882 0.671 rs4767024 chr12:113358791 T/C cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs12908161 1.000 rs34570071 chr15:85280212 T/A cg17507749 chr15:85114479 UBE2QP1 0.64 7.39 0.37 1.15e-12 Schizophrenia; LIHC cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.82 -15.85 -0.65 8.29e-43 Prudent dietary pattern; LIHC cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg18404041 chr3:52824283 ITIH1 -0.57 -9.16 -0.44 4.77e-18 Bipolar disorder; LIHC cis rs9522267 0.535 rs11069898 chr13:112231512 C/T cg10483660 chr13:112241077 NA -0.21 -5.75 -0.3 2.01e-8 Hepatitis; LIHC cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg04267008 chr7:1944627 MAD1L1 -0.68 -10.81 -0.5 1.3e-23 Bipolar disorder and schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17079137 chr17:27070735 TRAF4 0.48 6.51 0.33 2.61e-10 Lung function (FEV1/FVC); LIHC cis rs3008870 1.000 rs11208979 chr1:67442275 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs9916302 0.706 rs9646419 chr17:37597185 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -12.11 -0.55 2.54e-28 Glomerular filtration rate (creatinine); LIHC cis rs506338 0.517 rs1207179 chr11:64450795 C/T cg03263716 chr11:64435066 NRXN2 0.35 7.55 0.38 3.99e-13 Body mass index;Urate levels; LIHC cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.48 -6.81 -0.35 4.41e-11 Lymphocyte counts; LIHC cis rs2153535 0.504 rs5001323 chr6:8451605 C/T cg21535247 chr6:8435926 SLC35B3 0.62 8.15 0.4 6.79e-15 Motion sickness; LIHC cis rs4845459 0.967 rs4845446 chr1:152590750 C/T cg18116418 chr1:152553244 LCE3D 0.31 5.89 0.3 9.37e-9 Psoriasis; LIHC cis rs8067545 0.516 rs4925086 chr17:20013459 A/T cg13482628 chr17:19912719 NA 0.43 7.0 0.35 1.33e-11 Schizophrenia; LIHC cis rs6701037 0.714 rs2285219 chr1:175130983 A/T cg00321850 chr1:175162397 KIAA0040 -0.45 -7.1 -0.36 7.15e-12 Alcohol dependence; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg10755058 chr3:40428713 ENTPD3 0.4 7.15 0.36 5.15e-12 Renal cell carcinoma; LIHC trans rs12310956 0.532 rs10844719 chr12:33987714 A/G cg26384229 chr12:38710491 ALG10B 0.49 6.69 0.34 9.11e-11 Morning vs. evening chronotype; LIHC cis rs7412746 0.611 rs7532045 chr1:150821847 G/A cg17724175 chr1:150552817 MCL1 0.42 8.26 0.41 3.31e-15 Melanoma; LIHC cis rs1580019 0.562 rs4720064 chr7:32559638 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.6 8.86 0.43 4.49e-17 Cognitive ability; LIHC cis rs10489202 0.683 rs2294817 chr1:168073601 C/A cg24449463 chr1:168025552 DCAF6 -0.48 -6.63 -0.34 1.3100000000000001e-10 Schizophrenia; LIHC cis rs3011225 0.691 rs3791102 chr1:44366617 C/T cg12908607 chr1:44402522 ARTN -0.5 -8.38 -0.41 1.41e-15 Amyotrophic lateral sclerosis (age of onset); LIHC cis rs1552244 0.554 rs6796411 chr3:10010681 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -7.85 -0.39 5.25e-14 Alzheimer's disease; LIHC cis rs11625487 0.957 rs28820314 chr14:77963272 A/C cg20045696 chr14:77926864 AHSA1 -0.82 -7.67 -0.38 1.79e-13 Neutrophil percentage of white cells;Sum neutrophil eosinophil counts;Neutrophil count; LIHC cis rs116095464 0.558 rs10055354 chr5:243794 G/A cg22857025 chr5:266934 NA -1.39 -17.37 -0.68 6.99e-49 Breast cancer; LIHC cis rs1034435 0.547 rs6008741 chr22:48897881 G/A cg05992904 chr22:48892994 FAM19A5 -0.42 -7.61 -0.38 2.75e-13 Late-onset Alzheimer's disease; LIHC cis rs9325144 0.555 rs61929925 chr12:38698828 C/A cg26384229 chr12:38710491 ALG10B -0.58 -7.81 -0.39 7.1e-14 Morning vs. evening chronotype; LIHC cis rs875971 1.000 rs6958277 chr7:65979349 A/G cg18252515 chr7:66147081 NA -0.42 -5.98 -0.31 5.75e-9 Aortic root size; LIHC cis rs1256061 0.603 rs928554 chr14:64694195 C/T cg23250157 chr14:64679961 SYNE2 0.44 6.37 0.33 6.11e-10 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC trans rs7677751 0.806 rs4864862 chr4:55100489 G/A cg17183009 chr3:120277827 NA 0.52 6.08 0.31 3.18e-9 Corneal astigmatism; LIHC cis rs921968 0.643 rs2303561 chr2:219527005 C/T cg17980119 chr2:219472607 PLCD4 -0.34 -5.74 -0.3 2.14e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs875971 0.862 rs1695820 chr7:65844563 G/A cg18252515 chr7:66147081 NA -0.44 -6.34 -0.32 7.42e-10 Aortic root size; LIHC cis rs12915845 0.545 rs1583794 chr15:89076644 C/T cg05013243 chr15:89149849 MIR1179 -0.38 -6.73 -0.34 7.24e-11 Menarche (age at onset); LIHC cis rs7100689 0.646 rs1340384 chr10:82088702 T/A cg00277334 chr10:82204260 NA -0.57 -7.15 -0.36 5.22e-12 Post bronchodilator FEV1; LIHC cis rs1865760 0.892 rs2328903 chr6:25935765 T/C cg15691649 chr6:25882328 NA -0.39 -6.15 -0.32 2.11e-9 Height; LIHC cis rs1005277 0.541 rs1740741 chr10:38515334 C/T cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01069210 chr8:87518700 FAM82B 0.46 6.69 0.34 9.28e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7534824 0.543 rs12568993 chr1:101386259 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.62 7.49 0.38 6.07e-13 Refractive astigmatism; LIHC cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.75 0.8 3.26e-78 Prudent dietary pattern; LIHC cis rs7100689 0.646 rs2095994 chr10:82127956 G/A cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs1816752 0.905 rs2000153 chr13:24979890 G/A cg22771759 chr13:24902376 NA 0.35 6.59 0.34 1.71e-10 Obesity-related traits; LIHC cis rs16828019 0.852 rs16827876 chr1:41539536 T/G cg03387723 chr1:41708464 SCMH1 -0.4 -6.53 -0.33 2.42e-10 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09955859 chr1:40626914 RLF 0.41 6.06 0.31 3.65e-9 Pancreatic cancer; LIHC cis rs801193 0.636 rs10233806 chr7:66118248 G/C cg18252515 chr7:66147081 NA 0.45 6.53 0.33 2.38e-10 Aortic root size; LIHC cis rs763121 0.853 rs5757162 chr22:38993370 C/T cg14440974 chr22:39074834 NA -0.44 -6.98 -0.35 1.58e-11 Menopause (age at onset); LIHC cis rs13108904 0.604 rs11946375 chr4:1313488 T/C cg13395646 chr4:1353034 KIAA1530 -0.56 -9.17 -0.44 4.67e-18 Obesity-related traits; LIHC cis rs2549003 1.000 rs2706384 chr5:131826880 G/T cg21138405 chr5:131827807 IRF1 -0.4 -10.47 -0.49 1.96e-22 Asthma (sex interaction); LIHC cis rs4906332 1.000 rs12889703 chr14:103872951 T/A cg19000871 chr14:103996768 TRMT61A -0.45 -7.63 -0.38 2.35e-13 Coronary artery disease; LIHC cis rs2412488 0.927 rs11725230 chr4:54312072 T/C cg22241045 chr4:54363911 LNX1 -0.42 -6.79 -0.34 4.97e-11 DNA methylation (variation); LIHC cis rs2033711 0.870 rs7409473 chr19:58939165 A/G cg00825309 chr19:58991885 ZNF446 -0.64 -10.19 -0.48 1.8e-21 Uric acid clearance; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00776160 chr1:149815087 HIST2H2AA3;HIST2H2AA4 0.45 6.62 0.34 1.35e-10 Pancreatic cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg17524854 chr12:67663046 CAND1 0.44 6.43 0.33 4.33e-10 Pancreatic cancer; LIHC cis rs7249142 0.562 rs2314035 chr19:19284920 T/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.43 -7.11 -0.36 6.74e-12 IgG glycosylation; LIHC cis rs7534824 0.625 rs6699653 chr1:101499162 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 7.3 0.37 2.06e-12 Refractive astigmatism; LIHC cis rs6449957 0.577 rs7725370 chr5:67529752 G/A cg23036683 chr5:67512108 NA 0.42 6.05 0.31 3.73e-9 Cleft lip with or without cleft palate; LIHC cis rs1023500 0.506 rs6002625 chr22:42517689 A/G cg15557168 chr22:42548783 NA 0.45 7.06 0.36 9.21e-12 Schizophrenia; LIHC cis rs11190604 1.000 rs2489040 chr10:102331298 G/A cg07080220 chr10:102295463 HIF1AN 0.56 7.9 0.39 3.83e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2032447 0.531 rs428469 chr6:25898624 G/A cg03264133 chr6:25882463 NA -1.09 -14.05 -0.61 9.93e-36 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.557 rs4077531 chr11:1013167 G/A cg06064525 chr11:970664 AP2A2 -0.46 -11.17 -0.52 6.81e-25 Alzheimer's disease (late onset); LIHC cis rs1062177 1.000 rs2915877 chr5:151150601 C/G cg00977110 chr5:151150581 G3BP1 0.56 7.11 0.36 6.8e-12 Preschool internalizing problems; LIHC cis rs3770081 1.000 rs2278086 chr2:86281905 G/A cg01119172 chr2:86362222 SNORD94;PTCD3 0.58 9.34 0.45 1.32e-18 Facial emotion recognition (sad faces); LIHC cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09133386 chr6:20404188 E2F3 0.49 7.07 0.36 8.7e-12 Pancreatic cancer; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg12907513 chr18:9478896 RALBP1 -0.4 -6.3 -0.32 9.05e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6708331 0.540 rs11890701 chr2:70360457 T/A cg01613454 chr2:70366299 NA 0.38 6.11 0.31 2.75e-9 Obesity-related traits; LIHC cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.83 0.3 1.31e-8 Menopause (age at onset); LIHC cis rs9611565 0.592 rs5996038 chr22:41965300 T/C cg06634786 chr22:41940651 POLR3H -0.61 -6.53 -0.33 2.39e-10 Vitiligo; LIHC cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg22963979 chr7:1858916 MAD1L1 -0.38 -6.14 -0.31 2.35e-9 Schizophrenia; LIHC cis rs910316 0.839 rs35977276 chr14:75637359 A/C cg11812906 chr14:75593930 NEK9 -0.72 -13.66 -0.59 3.34e-34 Height; LIHC cis rs4803455 0.565 rs1025497 chr19:41871254 A/G cg08477640 chr19:41863820 B9D2 0.33 5.81 0.3 1.44e-8 Migraine;Coronary artery disease; LIHC cis rs7208859 0.623 rs75136574 chr17:28934549 C/A cg13385521 chr17:29058706 SUZ12P 0.7 6.72 0.34 7.7e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs459571 0.959 rs465535 chr9:136910905 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.52 -7.94 -0.39 2.86e-14 Platelet distribution width; LIHC trans rs4906332 1.000 rs17680085 chr14:103953154 T/C cg17675199 chr6:35436792 RPL10A 0.35 6.89 0.35 2.66e-11 Coronary artery disease; LIHC trans rs11098499 0.663 rs9996501 chr4:120238918 C/A cg25214090 chr10:38739885 LOC399744 0.53 8.57 0.42 3.6e-16 Corneal astigmatism; LIHC cis rs74233809 1.000 rs77787671 chr10:104776205 C/T cg03493300 chr10:104813866 CNNM2 0.46 6.19 0.32 1.75e-9 Birth weight; LIHC cis rs10489202 0.608 rs7533646 chr1:168077593 A/C cg17859187 chr1:168147929 TIPRL 0.41 5.72 0.3 2.27e-8 Schizophrenia; LIHC cis rs2439831 0.702 rs495175 chr15:43798684 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.46 0.59 1.96e-33 Lung cancer in ever smokers; LIHC cis rs9470366 0.545 rs6930083 chr6:36634156 A/G cg00935119 chr6:36647544 CDKN1A 0.44 6.23 0.32 1.4e-9 QRS duration; LIHC cis rs9549367 0.789 rs12584813 chr13:113895443 C/G cg18105134 chr13:113819100 PROZ -0.63 -10.7 -0.5 3.16e-23 Platelet distribution width; LIHC cis rs67311347 1.000 rs4973898 chr3:40459532 A/G cg10755058 chr3:40428713 ENTPD3 -0.35 -5.99 -0.31 5.41e-9 Renal cell carcinoma; LIHC trans rs634534 0.622 rs593525 chr11:65727799 T/C cg17712092 chr4:129076599 LARP1B 0.72 11.84 0.54 2.36e-27 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs9325144 0.513 rs7977596 chr12:38649067 C/A cg26384229 chr12:38710491 ALG10B -0.59 -8.11 -0.4 8.86e-15 Morning vs. evening chronotype; LIHC cis rs72781680 0.848 rs56371415 chr2:23932603 C/G cg08917208 chr2:24149416 ATAD2B 0.97 8.25 0.41 3.56e-15 Lymphocyte counts; LIHC cis rs2795502 0.873 rs3121327 chr10:43388285 G/A cg27426351 chr10:43362370 NA 0.47 5.78 0.3 1.64e-8 Blood protein levels; LIHC cis rs3808502 0.527 rs2736374 chr8:11113828 A/G cg02608752 chr8:10447774 NA 0.48 5.89 0.3 9.46e-9 Neuroticism; LIHC cis rs1127311 1.000 rs1127313 chr1:154556425 A/G cg17218026 chr1:154582156 ADAR -0.34 -6.45 -0.33 3.78e-10 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs1865760 0.713 rs7766342 chr6:25990674 C/A cg18357526 chr6:26021779 HIST1H4A 0.41 6.14 0.32 2.31e-9 Height; LIHC cis rs3768617 1.000 rs3820697 chr1:183100226 T/C ch.1.3577855R chr1:183094577 LAMC1 0.48 7.75 0.39 1.06e-13 Fuchs's corneal dystrophy; LIHC cis rs1018836 0.631 rs2205158 chr8:91472515 C/T cg16814680 chr8:91681699 NA -0.36 -5.88 -0.3 9.69e-9 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs7107174 0.901 rs2450138 chr11:77924870 C/T cg02023728 chr11:77925099 USP35 0.54 10.43 0.49 2.78e-22 Testicular germ cell tumor; LIHC cis rs2404602 0.647 rs12914196 chr15:76941361 C/T cg23625390 chr15:77176239 SCAPER -0.53 -8.74 -0.43 1.07e-16 Blood metabolite levels; LIHC cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg07061783 chr6:25882402 NA -0.48 -5.83 -0.3 1.25e-8 Intelligence (multi-trait analysis); LIHC cis rs950169 0.800 rs34302901 chr15:85110943 C/G cg12863693 chr15:85201151 NMB 0.41 5.76 0.3 1.85e-8 Schizophrenia; LIHC trans rs61931739 0.534 rs12372557 chr12:34363843 C/T cg26384229 chr12:38710491 ALG10B 0.74 9.18 0.44 4.31e-18 Morning vs. evening chronotype; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg05484376 chr2:27715224 FNDC4 0.37 6.31 0.32 8.4e-10 Total body bone mineral density; LIHC cis rs9868809 0.881 rs13063312 chr3:48661985 G/A cg07636037 chr3:49044803 WDR6 -0.55 -6.37 -0.33 6.24e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.47 0.62 2.36e-37 Prudent dietary pattern; LIHC cis rs1865760 0.534 rs2032444 chr6:26046744 T/G cg17691542 chr6:26056736 HIST1H1C 0.61 8.15 0.4 6.93e-15 Height; LIHC cis rs10197940 0.624 rs10497082 chr2:152355258 T/C cg19508488 chr2:152266495 RIF1 0.55 7.85 0.39 5.43e-14 Lung cancer; LIHC cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg08888203 chr3:10149979 C3orf24 0.54 6.49 0.33 3.05e-10 Alzheimer's disease; LIHC cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.12e-15 Prudent dietary pattern; LIHC cis rs6461049 0.800 rs3800913 chr7:2163237 A/G cg04267008 chr7:1944627 MAD1L1 -0.47 -7.26 -0.37 2.55e-12 Schizophrenia; LIHC cis rs243505 0.661 rs887570 chr7:148505255 A/G cg09806900 chr7:148480153 CUL1 0.44 6.52 0.33 2.52e-10 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6543140 0.964 rs2080288 chr2:103022166 G/A cg09003973 chr2:102972529 NA 0.53 6.04 0.31 4.09e-9 Blood protein levels; LIHC cis rs7312774 0.618 rs4964510 chr12:107357251 A/G cg16260113 chr12:107380972 MTERFD3 0.95 12.35 0.56 3.24e-29 Severe influenza A (H1N1) infection; LIHC cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.16 -0.32 2.1e-9 Colorectal cancer; LIHC cis rs7584330 0.868 rs13408361 chr2:238382899 A/G cg14458575 chr2:238380390 NA 0.43 6.68 0.34 9.84e-11 Prostate cancer; LIHC cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg11062466 chr8:58055876 NA 0.5 6.31 0.32 8.55e-10 Developmental language disorder (linguistic errors); LIHC trans rs72634258 0.836 rs7545687 chr1:7997183 G/A cg27488370 chr7:128046294 IMPDH1 -0.52 -6.18 -0.32 1.86e-9 Inflammatory bowel disease; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg05044401 chr4:54958559 NA 0.39 6.04 0.31 4.1e-9 Migraine with aura; LIHC cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.52 9.53 0.46 3.06e-19 Total body bone mineral density; LIHC cis rs6977660 1.000 rs5017194 chr7:19820035 A/T cg07541023 chr7:19748670 TWISTNB 0.36 5.74 0.3 2.1e-8 Thyroid stimulating hormone; LIHC cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.55 7.36 0.37 1.36e-12 Osteoporosis; LIHC cis rs80282103 0.618 rs7100114 chr10:1110231 A/G cg18964960 chr10:1102726 WDR37 0.66 5.85 0.3 1.16e-8 Glomerular filtration rate (creatinine); LIHC cis rs644799 0.710 rs10831429 chr11:95508524 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.78 13.46 0.59 1.97e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs611744 0.669 rs13251024 chr8:109258333 T/C cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs7927592 0.763 rs10896351 chr11:68386896 G/A cg01657329 chr11:68192670 LRP5 -0.5 -7.32 -0.37 1.82e-12 Total body bone mineral density; LIHC cis rs7208859 0.623 rs73271842 chr17:29137155 T/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4819052 0.565 rs35776291 chr21:46706142 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.64 10.15 0.48 2.41e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs62458065 0.513 rs10265319 chr7:32571564 A/C cg20159608 chr7:32802032 NA -0.48 -5.74 -0.3 2.14e-8 Metabolite levels (HVA/MHPG ratio); LIHC cis rs17854409 0.764 rs8116995 chr20:61475824 A/G cg06598544 chr20:61472147 COL9A3 -0.82 -7.99 -0.4 2.04e-14 Obesity-related traits; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg06951248 chr1:148244698 NA 0.28 6.32 0.32 8.21e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs6542838 0.609 rs12712043 chr2:99541494 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.52 -7.31 -0.37 1.86e-12 Fear of minor pain; LIHC cis rs2289328 0.823 rs35565646 chr15:40660515 G/A cg26241852 chr15:40650142 DISP2 -0.49 -6.1 -0.31 2.91e-9 Intelligence (multi-trait analysis);Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs909341 0.909 rs6122159 chr20:62370732 G/T cg03999872 chr20:62272968 STMN3 -0.44 -6.49 -0.33 2.93e-10 Atopic dermatitis; LIHC cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg16405210 chr4:1374714 KIAA1530 -0.57 -8.84 -0.43 5.26e-17 Obesity-related traits; LIHC cis rs634534 0.622 rs1192168 chr11:65730945 T/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.45 6.98 0.35 1.56e-11 Sum eosinophil basophil counts;Eosinophil counts; LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.68 9.84 0.47 2.81e-20 Lymphocyte counts; LIHC cis rs35110281 0.744 rs230645 chr21:44918607 A/G cg21573476 chr21:45109991 RRP1B 0.51 9.27 0.45 2.09e-18 Mean corpuscular volume; LIHC cis rs7810240 1.000 rs2888633 chr7:150083370 G/T cg10018233 chr7:150070692 REPIN1 0.4 6.46 0.33 3.51e-10 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; LIHC cis rs5769707 0.967 rs763126 chr22:49988574 G/T cg01652190 chr22:50026171 C22orf34 0.28 6.41 0.33 4.89e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs6952808 0.825 rs4236277 chr7:1942270 C/T cg21782813 chr7:2030301 MAD1L1 0.45 7.43 0.37 8.96e-13 Bipolar disorder and schizophrenia; LIHC cis rs7520050 0.843 rs1707334 chr1:46605728 A/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.45 6.74 0.34 6.93e-11 Red blood cell count;Reticulocyte count; LIHC cis rs853679 0.517 rs9368550 chr6:28051803 T/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 9.21e-11 Depression; LIHC cis rs67460515 0.563 rs4494975 chr3:160866768 C/T cg03342759 chr3:160939853 NMD3 -0.63 -9.12 -0.44 6.36e-18 Parkinson's disease; LIHC cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg00149659 chr3:10157352 C3orf10 0.7 7.1 0.36 7.09e-12 Alzheimer's disease; LIHC cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg08280861 chr8:58055591 NA 0.51 6.19 0.32 1.7e-9 Developmental language disorder (linguistic errors); LIHC cis rs903552 1.000 rs8041563 chr15:102005824 G/C cg25677261 chr15:102009856 PCSK6 -0.46 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC cis rs11098499 0.954 rs28429722 chr4:120300093 G/A cg09307838 chr4:120376055 NA 0.76 11.63 0.53 1.46e-26 Corneal astigmatism; LIHC cis rs644799 0.965 rs534488 chr11:95562327 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.76 0.47 5.37e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9399135 0.967 rs9373122 chr6:135373534 G/A cg22676075 chr6:135203613 NA 0.41 6.55 0.33 2.17e-10 Red blood cell count; LIHC cis rs10751667 0.643 rs10902238 chr11:944810 G/A cg10932868 chr11:921992 NA 0.38 7.34 0.37 1.59e-12 Alzheimer's disease (late onset); LIHC cis rs9473924 0.542 rs66834257 chr6:50809141 G/A cg14470998 chr6:50812995 TFAP2B 0.98 11.12 0.52 9.6e-25 Body mass index; LIHC cis rs4927850 0.709 rs6765762 chr3:195652851 G/A cg12923728 chr3:195709715 SDHAP1 -0.61 -6.2 -0.32 1.62e-9 Pancreatic cancer; LIHC cis rs6594499 0.872 rs10060003 chr5:110449357 A/G cg04022379 chr5:110408740 TSLP 0.5 8.29 0.41 2.64e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs11098499 0.913 rs10006304 chr4:120124305 A/G cg09307838 chr4:120376055 NA 0.53 7.88 0.39 4.54e-14 Corneal astigmatism; LIHC cis rs861318 0.702 rs3768519 chr1:159005224 C/G cg11003133 chr1:159046391 AIM2 -0.34 -6.48 -0.33 3.22e-10 Obesity-related traits; LIHC cis rs17125944 0.686 rs78623109 chr14:53383077 G/T cg00686598 chr14:53173677 PSMC6 0.88 9.44 0.45 5.84e-19 Alzheimer's disease (late onset); LIHC cis rs7927592 0.913 rs7104345 chr11:68316772 G/A cg20283391 chr11:68216788 NA -0.52 -7.85 -0.39 5.44e-14 Total body bone mineral density; LIHC cis rs796364 0.806 rs112305133 chr2:201010380 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.66 -7.66 -0.38 1.96e-13 Schizophrenia; LIHC cis rs7954584 0.520 rs1169094 chr12:122465535 A/G cg21016266 chr12:122356598 WDR66 -0.38 -5.98 -0.31 5.52e-9 Mean corpuscular volume; LIHC cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg25072359 chr17:41440525 NA 0.38 5.97 0.31 5.92e-9 Menopause (age at onset); LIHC cis rs523522 0.962 rs4766968 chr12:120947788 G/C cg12219531 chr12:120966889 COQ5 0.67 13.22 0.58 1.61e-32 High light scatter reticulocyte count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg21910613 chr1:27191950 NA 0.44 6.23 0.32 1.34e-9 Lung function (FEV1/FVC); LIHC cis rs17270561 0.723 rs12213243 chr6:25890108 C/T cg17691542 chr6:26056736 HIST1H1C 0.84 9.72 0.47 7.03e-20 Iron status biomarkers; LIHC cis rs7771547 0.573 rs10440841 chr6:36399086 G/A cg07856975 chr6:36356162 ETV7 -0.36 -5.86 -0.3 1.08e-8 Platelet distribution width; LIHC trans rs1814175 0.817 rs10128730 chr11:50023369 G/T cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs8180040 0.966 rs7651762 chr3:47470484 G/A cg27129171 chr3:47204927 SETD2 -0.58 -10.07 -0.48 4.47e-21 Colorectal cancer; LIHC cis rs6754311 0.593 rs10202489 chr2:136494186 G/A cg25344623 chr2:136566232 LCT 0.42 8.25 0.41 3.49e-15 Mosquito bite size; LIHC cis rs7224737 1.000 rs8070446 chr17:40285879 G/A cg20291162 chr17:40259547 DHX58 -0.39 -6.25 -0.32 1.26e-9 Fibrinogen levels; LIHC cis rs2070488 0.965 rs7433277 chr3:38529818 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.93 0.65 3.96e-43 Electrocardiographic conduction measures; LIHC cis rs700651 0.789 rs882954 chr2:198907444 A/G cg00792783 chr2:198669748 PLCL1 0.46 6.62 0.34 1.35e-10 Intracranial aneurysm; LIHC cis rs9467773 1.000 rs2224380 chr6:26553943 G/A cg11502198 chr6:26597334 ABT1 0.45 6.58 0.34 1.81e-10 Intelligence (multi-trait analysis); LIHC cis rs7551222 0.752 rs11240758 chr1:204528651 C/T cg20240347 chr1:204465584 NA -0.35 -7.38 -0.37 1.19e-12 Schizophrenia; LIHC cis rs66573146 1.000 rs56074877 chr4:6990374 C/T cg15105060 chr4:7024189 TBC1D14 -0.78 -6.28 -0.32 1.02e-9 Granulocyte percentage of myeloid white cells; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg02951274 chr4:3417431 RGS12 0.41 6.3 0.32 9.39e-10 Immature fraction of reticulocytes; LIHC cis rs6988636 1.000 rs10505430 chr8:124191933 A/G cg15893493 chr8:124194847 FAM83A -0.7 -7.02 -0.35 1.21e-11 Urinary uromodulin levels; LIHC cis rs7917772 0.502 rs2296584 chr10:104244323 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 12.49 0.56 9.88e-30 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs76533333 0.605 rs12867229 chr13:113422075 G/A cg08557188 chr13:113420371 ATP11A -0.75 -5.71 -0.3 2.43e-8 Red cell distribution width; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg10239991 chr2:240046227 HDAC4 0.45 6.19 0.32 1.76e-9 Hip circumference; LIHC trans rs116095464 0.558 rs10052012 chr5:231908 T/C cg00938859 chr5:1591904 SDHAP3 0.59 7.19 0.36 4.19e-12 Breast cancer; LIHC cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg10360323 chr17:41437877 NA 0.41 6.1 0.31 2.81e-9 Menopause (age at onset); LIHC cis rs7520050 0.966 rs4660319 chr1:46341623 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2576037 0.501 rs8089938 chr18:44459497 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.54 -7.94 -0.39 2.97e-14 Personality dimensions; LIHC cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs7772486 0.754 rs9497434 chr6:146260753 C/T cg13319975 chr6:146136371 FBXO30 0.37 6.01 0.31 4.87e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg11598736 chr3:195384522 SDHAP2 0.7 8.47 0.42 7.37e-16 Lung disease severity in cystic fibrosis; LIHC cis rs4808199 0.649 rs12983940 chr19:19516431 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.44 6.22 0.32 1.47e-9 Nonalcoholic fatty liver disease; LIHC cis rs4820294 0.547 rs62236743 chr22:38096053 T/C cg00142150 chr22:38071001 LGALS1 0.63 8.18 0.4 5.5e-15 Fat distribution (HIV); LIHC cis rs57502260 0.680 rs55654976 chr11:68393541 C/T cg20283391 chr11:68216788 NA -0.51 -6.33 -0.32 7.74e-10 Total body bone mineral density (age 45-60); LIHC cis rs7552404 1.000 rs7534754 chr1:76185308 G/A cg22875332 chr1:76189707 ACADM 0.48 7.0 0.35 1.39e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs3892630 0.824 rs7247264 chr19:33239846 T/G cg22980127 chr19:33182716 NUDT19 1.01 12.04 0.55 4.56e-28 Red blood cell traits; LIHC cis rs7769051 1.000 rs7765224 chr6:133101624 T/C cg07930552 chr6:133119739 C6orf192 0.71 6.85 0.35 3.46e-11 Type 2 diabetes nephropathy; LIHC cis rs9486715 0.838 rs9386473 chr6:96873341 C/A cg06623918 chr6:96969491 KIAA0776 0.84 14.53 0.62 1.36e-37 Headache; LIHC cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg14393609 chr7:65229607 NA 0.44 6.55 0.33 2.08e-10 Calcium levels; LIHC cis rs4974559 0.947 rs6847321 chr4:1347374 C/T cg02980000 chr4:1222292 CTBP1 0.6 7.06 0.36 9.6e-12 Systolic blood pressure; LIHC cis rs10089 0.904 rs2228112 chr5:127469859 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.54 6.69 0.34 8.95e-11 Ileal carcinoids; LIHC cis rs2153535 0.580 rs2327062 chr6:8453858 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.76 0.43 9.08e-17 Motion sickness; LIHC cis rs10870270 1.000 rs9971066 chr10:133788233 G/A cg08754478 chr10:133766260 PPP2R2D -0.53 -7.74 -0.39 1.17e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs4073582 0.595 rs708471 chr11:65931008 A/G cg16950941 chr11:66035639 RAB1B 0.55 8.28 0.41 2.73e-15 Gout; LIHC cis rs4631830 0.900 rs10763576 chr10:51538813 A/T cg20129853 chr10:51489980 NA -0.39 -8.53 -0.42 4.79e-16 Prostate-specific antigen levels; LIHC cis rs1552244 0.572 rs6797536 chr3:10168802 C/T cg02579736 chr3:10068473 FANCD2;CIDECP -0.92 -8.92 -0.43 2.92e-17 Alzheimer's disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07012231 chr7:47384322 TNS3 0.39 6.05 0.31 3.73e-9 Longevity; LIHC cis rs11893307 0.507 rs1465303 chr2:191585440 A/C cg10560079 chr2:191398806 TMEM194B -0.42 -6.08 -0.31 3.28e-9 Mean platelet volume; LIHC cis rs1707322 0.721 rs12069121 chr1:46231984 G/A cg06784218 chr1:46089804 CCDC17 0.42 7.51 0.38 5.13e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7731783 1 rs7731783 chr5:177060312 T/C cg26673648 chr5:177209285 NA 0.45 8.22 0.41 4.13e-15 Methadone dose in opioid dependence; LIHC cis rs3106136 0.900 rs13142645 chr4:95208714 A/G cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.01 -0.4 1.76e-14 Capecitabine sensitivity; LIHC cis rs875971 0.862 rs6952182 chr7:65683317 T/G cg11764359 chr7:65958608 NA -0.75 -12.45 -0.56 1.34e-29 Aortic root size; LIHC cis rs798554 0.797 rs798493 chr7:2798731 A/G cg19717773 chr7:2847554 GNA12 -0.42 -6.62 -0.34 1.38e-10 Height; LIHC cis rs7618501 0.669 rs2230590 chr3:49936102 T/C cg24110177 chr3:50126178 RBM5 -0.51 -7.95 -0.39 2.79e-14 Intelligence (multi-trait analysis); LIHC cis rs8180040 0.764 rs62246375 chr3:47014464 G/A cg02527881 chr3:46936655 PTH1R 0.33 6.59 0.34 1.62e-10 Colorectal cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg09015146 chr3:127308803 TPRA1 0.52 6.8 0.35 4.66e-11 Hepatitis; LIHC cis rs8056893 0.842 rs3785119 chr16:68374434 G/T cg02226672 chr16:68398533 SMPD3 0.42 5.89 0.3 9.02e-9 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg01238044 chr22:24384105 GSTT1 -0.43 -5.86 -0.3 1.09e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs711245 0.702 rs1110127 chr2:36768456 G/C cg09467607 chr2:36825704 FEZ2 0.47 6.99 0.35 1.47e-11 Height; LIHC cis rs2576037 0.526 rs571181 chr18:44376399 T/C cg24750912 chr18:44543259 TCEB3CL;KATNAL2 0.32 5.88 0.3 9.93e-9 Personality dimensions; LIHC cis rs2282032 0.527 rs2282033 chr14:90769635 G/T cg04374321 chr14:90722782 PSMC1 -0.48 -7.03 -0.36 1.13e-11 Longevity; LIHC cis rs3820068 0.581 rs72645874 chr1:15926238 C/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs16866061 1.000 rs10498163 chr2:225434445 A/G cg12698349 chr2:225449008 CUL3 0.8 13.92 0.6 3.16e-35 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs963731 0.649 rs1470915 chr2:39247336 G/A cg04010122 chr2:39346883 SOS1 -0.68 -5.84 -0.3 1.19e-8 Corticobasal degeneration; LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs769267 0.965 rs8101938 chr19:19390497 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.05 0.31 3.84e-9 Tonsillectomy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg03503634 chr11:36531973 TRAF6 0.45 6.35 0.32 6.69e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.601 rs4140584 chr6:8540614 C/G cg21535247 chr6:8435926 SLC35B3 -0.62 -8.1 -0.4 9.87e-15 Motion sickness; LIHC cis rs11229555 0.645 rs10896814 chr11:58430699 T/C cg15696309 chr11:58395628 NA -0.65 -6.14 -0.32 2.27e-9 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs1005277 0.563 rs2800550 chr10:38482929 T/C cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7e-9 Extrinsic epigenetic age acceleration; LIHC cis rs11792861 0.962 rs3750452 chr9:111801353 T/C cg05043794 chr9:111880884 C9orf5 -0.3 -7.01 -0.35 1.27e-11 Menarche (age at onset); LIHC cis rs425277 0.958 rs7546523 chr1:2043792 G/A cg24578937 chr1:2090814 PRKCZ 0.45 7.5 0.38 5.42e-13 Height; LIHC cis rs9388451 0.839 rs9401845 chr6:126104118 A/G cg05901451 chr6:126070800 HEY2 -0.73 -16.46 -0.66 3.14e-45 Brugada syndrome; LIHC cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.81 0.47 3.59e-20 Mean platelet volume; LIHC cis rs12220238 0.908 rs73284278 chr10:76011751 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.82 0.35 4.26e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs4803468 1.000 rs10422956 chr19:41901261 C/T cg09537434 chr19:41945824 ATP5SL -0.99 -20.61 -0.74 6.54e-62 Height; LIHC cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs17401966 0.838 rs12132134 chr1:10378428 A/G cg19773385 chr1:10388646 KIF1B -0.4 -7.29 -0.37 2.23e-12 Hepatocellular carcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25654697 chr7:7680075 RPA3 0.45 6.38 0.33 5.86e-10 Pancreatic cancer; LIHC cis rs782590 0.643 rs5012561 chr2:55742032 G/C cg03859395 chr2:55845619 SMEK2 -0.48 -7.81 -0.39 7.28e-14 Metabolic syndrome; LIHC cis rs4332037 0.619 rs78443464 chr7:1970229 C/T cg23422044 chr7:1970798 MAD1L1 -0.67 -7.54 -0.38 4.27e-13 Bipolar disorder; LIHC cis rs9325144 0.647 rs7487395 chr12:38865660 C/A cg26384229 chr12:38710491 ALG10B -0.56 -7.58 -0.38 3.24e-13 Morning vs. evening chronotype; LIHC trans rs1998584 1.000 rs10961199 chr9:13714854 G/T cg23692589 chr11:67256716 AIP 0.38 6.04 0.31 3.94e-9 Survival in microsatellite instability low/stable colorectal cancer; LIHC cis rs17685 0.712 rs2158867 chr7:75815141 C/A cg04610667 chr7:75704037 NA -0.33 -5.97 -0.31 5.83e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11958404 1.000 rs9686690 chr5:157412103 C/T cg05962755 chr5:157440814 NA 0.86 10.11 0.48 3.51e-21 IgG glycosylation; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg07677032 chr17:61819896 STRADA 0.41 5.95 0.31 6.66e-9 Prudent dietary pattern; LIHC cis rs4746818 1.000 rs10762259 chr10:70890929 C/T cg11621586 chr10:70884670 VPS26A 0.88 14.57 0.62 1e-37 Left atrial antero-posterior diameter; LIHC cis rs3204270 0.810 rs62077191 chr17:79678063 A/G cg18367735 chr17:79674897 NA 0.72 7.78 0.39 8.52e-14 Dental caries; LIHC cis rs918629 0.679 rs6883880 chr5:95271173 A/T cg10483112 chr5:95245456 ELL2 -0.37 -6.28 -0.32 1.04e-9 IgG glycosylation; LIHC cis rs7250872 0.568 rs749109 chr19:1819736 G/A cg18850929 chr19:1828978 REXO1 0.39 6.45 0.33 3.92e-10 Bipolar disorder; LIHC cis rs9733 0.596 rs12089989 chr1:150715782 G/A cg13175981 chr1:150552382 MCL1 -0.41 -5.83 -0.3 1.29e-8 Tonsillectomy; LIHC cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.57 -9.71 -0.47 7.4e-20 Bipolar disorder; LIHC cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg13047869 chr3:10149882 C3orf24 0.54 6.49 0.33 2.99e-10 Alzheimer's disease; LIHC cis rs909002 0.800 rs10914459 chr1:32096918 T/C cg13919466 chr1:32135498 COL16A1 -0.34 -6.41 -0.33 4.85e-10 Intelligence (multi-trait analysis); LIHC cis rs4706831 0.625 rs638056 chr6:80980808 G/A cg08355045 chr6:80787529 NA -0.3 -5.89 -0.3 9.06e-9 Joint mobility (Beighton score); LIHC trans rs1814175 0.817 rs6486046 chr11:49997017 T/C cg18944383 chr4:111397179 ENPEP 0.27 7.09 0.36 7.51e-12 Height; LIHC cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs2072499 0.966 rs2253677 chr1:156171296 C/G cg25208724 chr1:156163844 SLC25A44 -0.9 -15.65 -0.65 5.38e-42 Testicular germ cell tumor; LIHC cis rs1215050 0.740 rs783938 chr4:99010336 A/T cg05340658 chr4:99064831 C4orf37 -0.41 -6.43 -0.33 4.23e-10 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs250677 1.000 rs36079 chr5:148430504 G/A cg18129178 chr5:148520854 ABLIM3 -0.43 -7.02 -0.36 1.18e-11 Breast cancer; LIHC cis rs10779751 0.922 rs11121708 chr1:11307253 G/C cg08854313 chr1:11322531 MTOR 0.82 11.65 0.53 1.17e-26 Body mass index; LIHC cis rs11148252 0.595 rs9526974 chr13:53251040 C/G cg02158880 chr13:53174818 NA 0.37 5.85 0.3 1.13e-8 Lewy body disease; LIHC trans rs3809912 0.595 rs12605006 chr18:12992261 C/G cg02139827 chr21:34404457 NA 0.24 6.23 0.32 1.34e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs589448 0.967 rs2617835 chr12:69753420 C/A cg22834771 chr12:69754056 YEATS4 -0.55 -9.97 -0.47 1.02e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs79387448 0.638 rs116055209 chr2:103032189 C/T cg09003973 chr2:102972529 NA 1.1 9.28 0.45 2.03e-18 Gut microbiota (bacterial taxa); LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg02990361 chr1:107599529 PRMT6 0.65 11.02 0.51 2.28e-24 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs66887589 0.616 rs11098498 chr4:120187119 T/C cg25214090 chr10:38739885 LOC399744 0.42 6.68 0.34 9.96e-11 Diastolic blood pressure; LIHC cis rs16828019 0.929 rs4131949 chr1:41738637 C/T cg03962019 chr1:41807865 NA 0.5 7.22 0.36 3.3e-12 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs2911713 chr2:27640980 G/A cg21747090 chr2:27597821 SNX17 -0.44 -6.71 -0.34 8.05e-11 Total body bone mineral density; LIHC cis rs3106136 0.814 rs6532481 chr4:95277311 T/G cg11021082 chr4:95130006 SMARCAD1 0.39 6.63 0.34 1.33e-10 Capecitabine sensitivity; LIHC cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg15691649 chr6:25882328 NA -0.53 -7.65 -0.38 2.07e-13 Blood metabolite levels; LIHC cis rs7116495 1.000 rs1791544 chr11:71784957 G/A cg26138937 chr11:71823887 C11orf51 -0.67 -6.76 -0.34 5.8200000000000003e-11 Severe influenza A (H1N1) infection; LIHC cis rs3820500 0.543 rs1934249 chr1:118049831 A/T cg20383390 chr1:117909022 MAN1A2 -0.48 -6.1 -0.31 2.94e-9 Pneumonia; LIHC cis rs7208859 0.623 rs8079891 chr17:29058863 G/A cg13385521 chr17:29058706 SUZ12P 0.84 8.37 0.41 1.49e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9324022 0.860 rs72698720 chr14:101178715 C/G cg18089426 chr14:101175970 NA 0.48 5.92 0.3 8.04e-9 Plateletcrit; LIHC cis rs12477438 0.798 rs1530996 chr2:99584079 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.73 -10.89 -0.51 6.82e-24 Chronic sinus infection; LIHC cis rs11822910 1.000 rs11822910 chr11:57195917 G/A cg00522883 chr11:57194120 SLC43A3 0.7 8.4 0.41 1.18e-15 Platelet distribution width; LIHC cis rs72843506 0.656 rs73981807 chr17:19996230 C/G cg12065943 chr17:19881925 AKAP10 -0.33 -5.8 -0.3 1.53e-8 Schizophrenia; LIHC cis rs9926296 0.607 rs11076629 chr16:89875259 T/C cg27121462 chr16:89883253 FANCA 0.42 6.72 0.34 7.48e-11 Vitiligo; LIHC cis rs875971 0.545 rs1547529 chr7:65723846 T/C cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.45 0.37 7.63e-13 Aortic root size; LIHC cis rs6430585 0.583 rs2304371 chr2:136561557 A/G cg07305463 chr2:136567211 LCT -0.37 -5.86 -0.3 1.1e-8 Corneal structure; LIHC cis rs2228479 0.702 rs17233176 chr16:89832751 G/C cg06558623 chr16:89946397 TCF25 0.85 11.71 0.53 7.62e-27 Skin colour saturation; LIHC cis rs743757 1.000 rs743756 chr3:50481717 C/T cg05260129 chr3:50388622 TUSC4;CYB561D2 0.44 6.19 0.32 1.7e-9 Diastolic blood pressure; LIHC cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg11062466 chr8:58055876 NA 0.51 7.61 0.38 2.72e-13 Developmental language disorder (linguistic errors); LIHC cis rs7582720 1.000 rs72926793 chr2:203826396 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs4713118 0.662 rs9393881 chr6:28023751 C/G cg16479474 chr6:28041457 NA 0.45 7.04 0.36 1.08e-11 Parkinson's disease; LIHC cis rs7072216 0.763 rs942805 chr10:100168372 G/A cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC cis rs16854884 0.657 rs16854772 chr3:143703890 A/G cg06585982 chr3:143692056 C3orf58 0.57 7.53 0.38 4.44e-13 Economic and political preferences (feminism/equality); LIHC trans rs2739330 0.791 rs4822458 chr22:24265659 C/T cg06437703 chr8:37914619 EIF4EBP1 -0.56 -8.71 -0.43 1.35e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11924390 0.800 rs5030059 chr3:186452455 C/G cg12454167 chr3:186435060 KNG1 0.32 7.68 0.38 1.73e-13 Adiponectin levels; LIHC cis rs11758351 0.866 rs56186759 chr6:26207181 C/T cg06951627 chr6:26196580 NA 0.53 6.27 0.32 1.07e-9 Gout;Renal underexcretion gout; LIHC cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.47 0.56 1.09e-29 Prudent dietary pattern; LIHC cis rs7772486 0.875 rs1125461 chr6:146417653 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.24 0.32 1.33e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1878931 0.615 rs4786412 chr16:3440390 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 22.17 0.77 3.9e-68 Body mass index (adult); LIHC cis rs826838 0.967 rs7963716 chr12:38876090 C/T cg26384229 chr12:38710491 ALG10B 0.96 12.6 0.56 3.67e-30 Heart rate; LIHC cis rs35146811 0.771 rs1060544 chr7:99613476 C/T cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.4 5.74 0.3 2.08e-8 Coronary artery disease; LIHC cis rs6089584 0.586 rs2296087 chr20:60584328 T/A cg06108461 chr20:60628389 TAF4 -0.52 -6.76 -0.34 6.05e-11 Body mass index; LIHC trans rs2797160 0.967 rs2747718 chr6:126009109 C/A cg05039488 chr6:79577232 IRAK1BP1 0.46 6.5 0.33 2.88e-10 Endometrial cancer; LIHC cis rs9402673 0.558 rs9688342 chr6:135323026 A/T cg22676075 chr6:135203613 NA 0.38 6.19 0.32 1.73e-9 Reticulocyte count;High light scatter reticulocyte count; LIHC cis rs7100689 0.646 rs2039757 chr10:82078868 C/A cg01528321 chr10:82214614 TSPAN14 0.77 10.34 0.49 5.36e-22 Post bronchodilator FEV1; LIHC cis rs860626 0.583 rs855766 chr10:119316158 A/G cg10846980 chr10:119306025 EMX2;EMX2OS -0.52 -8.09 -0.4 1.02e-14 Neuroticism; LIHC cis rs2290416 0.892 rs76108894 chr8:144673533 G/A cg26536354 chr8:144654954 C8orf73 0.54 6.22 0.32 1.41e-9 Attention deficit hyperactivity disorder; LIHC cis rs2576037 0.796 rs2571020 chr18:44584189 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.49 -7.42 -0.37 9.09e-13 Personality dimensions; LIHC cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg05590025 chr7:65112418 INTS4L2 -0.6 -6.57 -0.33 1.88e-10 Diabetic kidney disease; LIHC cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg07061783 chr6:25882402 NA 0.65 8.23 0.41 4.06e-15 Blood metabolite levels; LIHC cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg03264133 chr6:25882463 NA -0.6 -8.4 -0.41 1.21e-15 Blood metabolite levels; LIHC cis rs6977660 0.714 rs4721824 chr7:19785898 A/G cg07541023 chr7:19748670 TWISTNB 0.48 7.03 0.36 1.13e-11 Thyroid stimulating hormone; LIHC cis rs1577917 1.000 rs7756203 chr6:86627707 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.99 -0.35 1.49e-11 Response to antipsychotic treatment; LIHC cis rs897984 0.520 rs4889536 chr16:30871755 G/T cg02466173 chr16:30829666 NA 0.48 7.26 0.37 2.55e-12 Dementia with Lewy bodies; LIHC cis rs1577917 0.958 rs7747897 chr6:86647349 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -7.05 -0.36 9.81e-12 Response to antipsychotic treatment; LIHC cis rs9486719 0.843 rs1009597 chr6:96843540 A/T cg06623918 chr6:96969491 KIAA0776 0.68 6.64 0.34 1.24e-10 Migraine;Coronary artery disease; LIHC cis rs600806 0.742 rs9429519 chr1:110017105 A/G cg08911820 chr1:110026001 ATXN7L2 0.52 6.59 0.34 1.67e-10 Intelligence (multi-trait analysis); LIHC cis rs765787 0.530 rs28815867 chr15:45526805 G/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.78 -0.3 1.71e-8 Uric acid levels; LIHC cis rs9300255 0.568 rs1621194 chr12:123651018 T/C cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg06481639 chr22:41940642 POLR3H -0.72 -7.18 -0.36 4.37e-12 Vitiligo; LIHC cis rs4742903 0.904 rs4743691 chr9:106931541 G/A cg14250997 chr9:106856677 SMC2 0.36 6.05 0.31 3.91e-9 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs8180040 0.620 rs1811652 chr3:47208698 C/G cg16586182 chr3:47516702 SCAP 0.48 8.45 0.42 8.71e-16 Colorectal cancer; LIHC cis rs74181299 0.684 rs2052261 chr2:65355270 G/A cg05010058 chr2:65284262 CEP68 -0.41 -6.67 -0.34 1.06e-10 Pulse pressure; LIHC cis rs12477438 0.798 rs6759354 chr2:99632195 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -10.77 -0.5 1.69e-23 Chronic sinus infection; LIHC cis rs7312933 0.898 rs10880221 chr12:42384589 C/A cg01256987 chr12:42539512 GXYLT1 -0.38 -6.27 -0.32 1.12e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6141600 0.540 rs1006296 chr20:34717718 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.4 -6.49 -0.33 2.97e-10 Height;Hip circumference; LIHC cis rs7700895 0.737 rs10035477 chr5:95227507 C/T cg10483112 chr5:95245456 ELL2 0.34 5.95 0.31 6.75e-9 IgG glycosylation; LIHC cis rs965469 0.779 rs6051770 chr20:3327014 A/G cg25506879 chr20:3388711 C20orf194 -0.53 -6.54 -0.33 2.22e-10 IFN-related cytopenia; LIHC trans rs7615952 1.000 rs7616044 chr3:125649354 G/C cg07211511 chr3:129823064 LOC729375 -0.85 -10.74 -0.5 2.29e-23 Blood pressure (smoking interaction); LIHC cis rs1552244 0.882 rs35056669 chr3:10014171 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.72 9.97 0.47 1.03e-20 Alzheimer's disease; LIHC cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg15691649 chr6:25882328 NA 0.83 11.35 0.52 1.43e-25 Blood metabolite levels; LIHC cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg21782813 chr7:2030301 MAD1L1 0.56 10.27 0.49 9.91e-22 Bipolar disorder and schizophrenia; LIHC cis rs11792861 0.926 rs72607173 chr9:111879398 T/G cg05043794 chr9:111880884 C9orf5 -0.28 -6.36 -0.33 6.32e-10 Menarche (age at onset); LIHC cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg13409248 chr3:40428643 ENTPD3 -0.42 -6.96 -0.35 1.76e-11 Renal cell carcinoma; LIHC trans rs16863064 0.866 rs9855318 chr3:187887381 C/T cg02569115 chr17:76922138 TIMP2 -0.35 -6.17 -0.32 1.94e-9 Schizophrenia; LIHC cis rs10463316 0.784 rs906678 chr5:150779040 T/C cg03212797 chr5:150827313 SLC36A1 -0.4 -5.9 -0.3 8.89e-9 Metabolite levels (Pyroglutamine); LIHC cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg06481639 chr22:41940642 POLR3H -0.72 -6.84 -0.35 3.55e-11 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9399135 1.000 rs4896130 chr6:135355118 C/T cg24558204 chr6:135376177 HBS1L 0.41 6.8 0.34 4.78e-11 Red blood cell count; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05651185 chr6:125421530 NA -0.37 -6.18 -0.32 1.79e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6500602 0.893 rs4785962 chr16:4484328 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.37 0.33 5.93e-10 Schizophrenia; LIHC cis rs2130392 1.000 rs873686 chr4:185638876 A/G cg21366198 chr4:185655624 MLF1IP 0.57 9.04 0.44 1.19e-17 Kawasaki disease; LIHC cis rs1707322 1.000 rs785486 chr1:46575148 G/C cg06784218 chr1:46089804 CCDC17 -0.37 -6.75 -0.34 6.35e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs6489882 0.867 rs6489870 chr12:113363972 G/A cg10175203 chr3:128143634 NA 0.39 6.39 0.33 5.57e-10 Chronic lymphocytic leukemia; LIHC cis rs13191362 1.000 rs13190742 chr6:163008758 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.84 0.3 1.22e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg08484479 chr5:887419 BRD9 0.43 6.16 0.32 2e-9 Alopecia areata; LIHC trans rs7618501 0.699 rs9821675 chr3:49902544 A/G cg21659725 chr3:3221576 CRBN 0.74 11.45 0.53 6.25e-26 Intelligence (multi-trait analysis); LIHC cis rs7918232 0.941 rs788210 chr10:27476948 T/C cg14442939 chr10:27389572 ANKRD26 -0.74 -7.06 -0.36 9.19e-12 Breast cancer; LIHC cis rs9326248 0.813 rs7115562 chr11:117020470 A/G cg11861562 chr11:117069780 TAGLN 0.36 5.71 0.3 2.43e-8 Blood protein levels; LIHC cis rs6964587 1.000 rs6951972 chr7:91689446 T/G cg17063962 chr7:91808500 NA 1.02 19.56 0.73 1.02e-57 Breast cancer; LIHC cis rs798554 0.679 rs2644281 chr7:2886748 A/G cg04166393 chr7:2884313 GNA12 0.52 8.36 0.41 1.57e-15 Height; LIHC cis rs6582630 0.555 rs2004152 chr12:38478951 C/T cg26384229 chr12:38710491 ALG10B 0.96 12.33 0.55 3.76e-29 Drug-induced liver injury (flucloxacillin); LIHC cis rs11148252 0.904 rs9568734 chr13:53004222 G/A cg00495681 chr13:53174319 NA 0.42 7.02 0.35 1.2e-11 Lewy body disease; LIHC trans rs2073499 1.000 rs10510755 chr3:50281168 C/T cg21659725 chr3:3221576 CRBN 0.62 6.23 0.32 1.39e-9 Schizophrenia; LIHC cis rs1577917 0.739 rs9450318 chr6:86427177 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.38 7.09 0.36 7.59e-12 Response to antipsychotic treatment; LIHC cis rs68170813 0.559 rs76933738 chr7:106814574 T/C cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs782590 0.967 rs10496050 chr2:55806313 C/T cg18811423 chr2:55921094 PNPT1 0.92 14.9 0.63 4.96e-39 Metabolic syndrome; LIHC cis rs9303401 0.614 rs34843288 chr17:57103140 T/C cg25039879 chr17:56429692 SUPT4H1 0.78 8.78 0.43 7.79e-17 Cognitive test performance; LIHC cis rs11608355 0.545 rs7315846 chr12:109908617 T/C cg05360138 chr12:110035743 NA 0.95 10.92 0.51 5.16e-24 Neuroticism; LIHC cis rs1982963 0.906 rs2029976 chr14:52505811 C/T cg10843707 chr14:52510701 NID2 -0.44 -7.7 -0.38 1.51e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg10755058 chr3:40428713 ENTPD3 -0.34 -5.96 -0.31 6.33e-9 Renal cell carcinoma; LIHC cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.49 0.38 5.91e-13 Electroencephalogram traits; LIHC cis rs919433 0.680 rs1563340 chr2:198414713 A/T cg10820045 chr2:198174542 NA 0.54 8.57 0.42 3.49e-16 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs34245846 0.704 rs11264278 chr1:154845534 G/C cg24250549 chr1:154909240 PMVK -0.67 -9.09 -0.44 8.01e-18 Atrial fibrillation; LIHC cis rs10916814 0.588 rs4571937 chr1:20897033 G/A cg24502330 chr1:20914028 CDA -0.31 -6.93 -0.35 2.13e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7945705 0.905 rs2568054 chr11:8876029 A/G cg12365402 chr11:9010492 NRIP3 -0.23 -5.88 -0.3 9.54e-9 Hemoglobin concentration; LIHC cis rs7772486 0.623 rs9485021 chr6:146068797 A/G cg23711669 chr6:146136114 FBXO30 -0.63 -11.49 -0.53 4.79e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs8078723 0.705 rs8065443 chr17:38208940 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.55 8.69 0.43 1.48e-16 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs60871478 0.898 rs4725241 chr7:796883 C/T cg05535760 chr7:792225 HEATR2 0.8 11.35 0.52 1.55e-25 Cerebrospinal P-tau181p levels; LIHC cis rs11971779 0.715 rs6943973 chr7:139029893 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.22 0.48 1.41e-21 Diisocyanate-induced asthma; LIHC cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg00656387 chr3:40428638 ENTPD3 0.49 8.35 0.41 1.78e-15 Renal cell carcinoma; LIHC cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.9 14.13 0.61 5.21e-36 Alzheimer's disease; LIHC cis rs897984 0.568 rs67264578 chr16:30879395 G/A cg02466173 chr16:30829666 NA -0.44 -6.71 -0.34 8.16e-11 Dementia with Lewy bodies; LIHC cis rs9814567 0.537 rs9879993 chr3:134162559 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.42 7.63 0.38 2.3e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4834770 1.000 rs6823963 chr4:120242164 A/C cg09307838 chr4:120376055 NA 0.43 6.5 0.33 2.87e-10 Blood protein levels; LIHC cis rs2997447 0.846 rs3008231 chr1:26402023 A/G cg19633962 chr1:26362018 EXTL1 -0.48 -5.86 -0.3 1.1e-8 QRS complex (12-leadsum); LIHC cis rs7116495 0.609 rs7121080 chr11:71703935 G/A cg10381502 chr11:71823885 C11orf51 -1.0 -8.62 -0.42 2.6e-16 Severe influenza A (H1N1) infection; LIHC cis rs9814567 1.000 rs6793487 chr3:134299426 C/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.26 0.32 1.13e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8114671 0.967 rs6088747 chr20:33754604 G/T cg07148914 chr20:33460835 GGT7 0.41 5.78 0.3 1.72e-8 Height; LIHC cis rs11031096 0.502 rs720571 chr11:4001328 G/T cg18678763 chr11:4115507 RRM1 -0.58 -8.57 -0.42 3.58e-16 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs2072499 0.966 rs6427304 chr1:156156789 A/G cg24450063 chr1:156163899 SLC25A44 1.03 16.8 0.67 1.27e-46 Testicular germ cell tumor; LIHC cis rs6429082 0.755 rs291370 chr1:235693041 A/G cg26050004 chr1:235667680 B3GALNT2 0.46 7.42 0.37 9.3e-13 Adiposity; LIHC cis rs35110281 0.641 rs9978858 chr21:45085552 A/G cg01579765 chr21:45077557 HSF2BP -0.35 -6.06 -0.31 3.64e-9 Mean corpuscular volume; LIHC cis rs1865721 1.000 rs17283692 chr18:73193911 T/C cg26385618 chr18:73139727 C18orf62 -0.3 -7.64 -0.38 2.17e-13 Intelligence; LIHC cis rs826838 0.804 rs6580755 chr12:39159190 C/T cg26384229 chr12:38710491 ALG10B 0.88 11.47 0.53 5.27e-26 Heart rate; LIHC cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.5 0.38 5.37e-13 Electroencephalogram traits; LIHC cis rs4243830 0.737 rs11122088 chr1:6603677 T/G cg22792644 chr1:6614718 TAS1R1;NOL9 -0.84 -9.45 -0.46 5.47e-19 Body mass index; LIHC cis rs7582720 1.000 rs72934563 chr2:203995405 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.73 5.88 0.3 9.6e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs739401 0.572 rs7111857 chr11:3068106 A/G cg25174290 chr11:3078921 CARS -0.67 -10.22 -0.48 1.48e-21 Longevity; LIHC cis rs317689 0.819 rs317660 chr12:69686203 G/A cg22834771 chr12:69754056 YEATS4 -0.39 -5.71 -0.3 2.4e-8 Response to diuretic therapy; LIHC cis rs8067354 0.574 rs2531899 chr17:58007193 A/G cg02344993 chr17:57696989 CLTC -0.66 -10.46 -0.49 2.16e-22 Hemoglobin concentration; LIHC cis rs3818285 0.655 rs588160 chr10:111641538 C/T cg00817464 chr10:111662876 XPNPEP1 0.65 10.9 0.51 6.3e-24 Superior crus of antihelix expression; LIHC cis rs516243 0.703 rs284313 chr1:10736434 A/G cg02903756 chr1:10750680 CASZ1 -0.34 -6.09 -0.31 3.1e-9 Migraine - clinic-based; LIHC cis rs9858542 0.537 rs9863142 chr3:49366741 C/G cg00383909 chr3:49044727 WDR6 0.6 6.02 0.31 4.55e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs6543140 0.964 rs6736135 chr2:103064924 A/G cg09003973 chr2:102972529 NA 0.52 5.81 0.3 1.42e-8 Blood protein levels; LIHC cis rs7940866 0.774 rs2162059 chr11:130831224 C/T cg12179176 chr11:130786555 SNX19 0.65 9.56 0.46 2.34e-19 Schizophrenia; LIHC trans rs1814175 0.817 rs6486044 chr11:49982718 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -23.67 -0.79 5e-74 Height; LIHC cis rs10504229 0.773 rs60466370 chr8:58171248 A/C cg21724239 chr8:58056113 NA 0.46 6.08 0.31 3.23e-9 Developmental language disorder (linguistic errors); LIHC cis rs9381040 0.610 rs2294694 chr6:41046177 G/A cg04346459 chr6:41068666 NFYA;LOC221442 -0.4 -6.22 -0.32 1.44e-9 Alzheimer's disease (late onset); LIHC cis rs4713118 0.869 rs9461401 chr6:27703291 G/A cg20933634 chr6:27740509 NA 0.47 6.21 0.32 1.56e-9 Parkinson's disease; LIHC cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg06618935 chr21:46677482 NA -0.3 -5.73 -0.3 2.23e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.66 0.38 1.89e-13 Prudent dietary pattern; LIHC cis rs12220238 1.000 rs11000922 chr10:75969305 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.52 0.33 2.54e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1865721 1.000 rs62089503 chr18:73177766 C/T cg26385618 chr18:73139727 C18orf62 -0.3 -7.67 -0.38 1.79e-13 Intelligence; LIHC cis rs7552404 0.960 rs4949877 chr1:76201668 C/G cg10523679 chr1:76189770 ACADM 0.63 8.72 0.43 1.2e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg17971929 chr21:40555470 PSMG1 -0.51 -7.66 -0.38 1.97e-13 Cognitive function; LIHC cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg16132339 chr22:24313637 DDTL;DDT -0.75 -14.2 -0.61 2.63e-36 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7572733 0.515 rs6726506 chr2:198846486 G/T cg03934865 chr2:198174659 NA 0.46 6.61 0.34 1.44e-10 Dermatomyositis; LIHC cis rs6912958 0.500 rs2025486 chr6:87796886 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.37 -5.89 -0.3 9.1e-9 Monocyte percentage of white cells; LIHC cis rs738322 0.718 rs3761445 chr22:38595411 G/A cg25457927 chr22:38595422 NA 0.44 11.32 0.52 1.95e-25 Cutaneous nevi; LIHC cis rs7131987 0.683 rs3782511 chr12:29496224 G/A cg14222432 chr12:29376421 FAR2 0.33 6.04 0.31 4e-9 QT interval; LIHC cis rs477895 1.000 rs1047206 chr11:64089216 C/G cg04317338 chr11:64019027 PLCB3 0.85 7.93 0.39 3.14e-14 Mean platelet volume; LIHC cis rs8081395 0.603 rs1292047 chr17:57955166 C/T cg13753209 chr17:57696993 CLTC 0.49 7.77 0.39 9.07e-14 White blood cell count; LIHC cis rs1395 1.000 rs1141313 chr2:27460968 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.4 -5.81 -0.3 1.41e-8 Blood metabolite levels; LIHC cis rs62229266 0.605 rs11701331 chr21:37458392 T/C cg12218747 chr21:37451666 NA -0.43 -7.08 -0.36 8.27e-12 Mitral valve prolapse; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg02782426 chr3:40428986 ENTPD3 -0.34 -6.45 -0.33 3.77e-10 Renal cell carcinoma; LIHC trans rs11039798 0.764 rs2089208 chr11:48899860 C/T cg15704280 chr7:45808275 SEPT13 0.61 6.36 0.33 6.42e-10 Axial length; LIHC cis rs2073499 1.000 rs2071802 chr3:50412945 A/G cg12708802 chr3:50388878 TUSC4;CYB561D2 0.7 7.2 0.36 3.79e-12 Schizophrenia; LIHC cis rs4950322 0.576 rs11240015 chr1:146852534 A/G cg25205988 chr1:146714368 CHD1L -0.41 -5.95 -0.31 6.75e-9 Protein quantitative trait loci; LIHC cis rs422249 0.512 rs174562 chr11:61585144 A/G cg27386326 chr11:61587980 NA 0.7 14.62 0.62 6.07e-38 Trans fatty acid levels; LIHC cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs703842 1.000 rs10877019 chr12:58172929 A/G cg04478727 chr12:58166393 METTL1;FAM119B -0.86 -13.79 -0.6 1.02e-34 Multiple sclerosis; LIHC cis rs7582180 0.614 rs4340543 chr2:101005511 G/A cg14675211 chr2:100938903 LONRF2 0.56 8.26 0.41 3.22e-15 Intelligence (multi-trait analysis); LIHC cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg26338869 chr17:61819248 STRADA 0.55 7.93 0.39 3.04e-14 Prudent dietary pattern; LIHC trans rs4824093 0.610 rs7410773 chr22:50313727 A/G cg09872104 chr7:134855509 C7orf49 -0.76 -6.19 -0.32 1.68e-9 Amyotrophic lateral sclerosis (sporadic); LIHC cis rs1395 0.778 rs56364136 chr2:27451429 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -5.83 -0.3 1.27e-8 Blood metabolite levels; LIHC cis rs861318 0.702 rs3768523 chr1:159003998 G/C cg11003133 chr1:159046391 AIM2 -0.34 -6.55 -0.33 2.06e-10 Obesity-related traits; LIHC trans rs12210761 0.511 rs12193757 chr6:10151450 C/T cg10354244 chr20:57090090 APCDD1L -0.57 -6.2 -0.32 1.61e-9 Major depressive disorder; LIHC cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg21280719 chr6:42927975 GNMT 0.33 7.31 0.37 1.88e-12 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1790761 0.692 rs638140 chr11:67333858 G/C cg21734168 chr11:67353974 GSTP1 -0.27 -6.76 -0.34 6.08e-11 Mean corpuscular volume; LIHC cis rs4919694 0.711 rs113361908 chr10:104978126 T/C cg04362960 chr10:104952993 NT5C2 0.95 7.23 0.36 3.28e-12 Arsenic metabolism; LIHC cis rs2070488 0.965 rs7373828 chr3:38524311 A/G cg24069376 chr3:38537580 EXOG 0.41 7.47 0.37 6.82e-13 Electrocardiographic conduction measures; LIHC cis rs9393692 0.846 rs9366651 chr6:26336696 G/T cg05868516 chr6:26286170 HIST1H4H 0.38 5.84 0.3 1.19e-8 Educational attainment; LIHC cis rs3806843 0.966 rs7710380 chr5:140156264 T/C cg19875535 chr5:140030758 IK 0.37 6.04 0.31 3.97e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs875971 0.638 rs3898855 chr7:66036398 G/C cg14393609 chr7:65229607 NA -0.37 -5.84 -0.3 1.22e-8 Aortic root size; LIHC cis rs6748734 0.901 rs6720357 chr2:241830296 A/C cg20140201 chr2:241835670 C2orf54 -0.47 -6.45 -0.33 3.9e-10 Urinary metabolites; LIHC cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.16 -0.55 1.61e-28 Alzheimer's disease; LIHC cis rs2303759 0.918 rs7251704 chr19:49890873 T/G cg24324837 chr19:49891574 CCDC155 0.39 6.11 0.31 2.75e-9 Multiple sclerosis; LIHC cis rs7927592 0.513 rs3853616 chr11:68198252 A/G cg01657329 chr11:68192670 LRP5 -0.55 -8.11 -0.4 9.29e-15 Total body bone mineral density; LIHC cis rs1707322 1.000 rs1612419 chr1:46546945 T/C cg03146154 chr1:46216737 IPP -0.46 -7.29 -0.37 2.2e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs769267 0.896 rs2315610 chr19:19597240 T/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.91 0.3 8.45e-9 Tonsillectomy; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg00280220 chr17:61926910 NA 0.44 7.07 0.36 8.7e-12 Prudent dietary pattern; LIHC cis rs10924970 0.967 rs12027832 chr1:235385934 A/G cg26050004 chr1:235667680 B3GALNT2 0.39 5.75 0.3 1.94e-8 Asthma; LIHC cis rs12893668 0.603 rs12896171 chr14:104135966 A/G cg24130564 chr14:104152367 KLC1 -0.55 -9.5 -0.46 3.67e-19 Reticulocyte count; LIHC cis rs11122272 0.735 rs2491412 chr1:231535880 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.64 -10.27 -0.49 9.53e-22 Hemoglobin concentration; LIHC cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg23758822 chr17:41437982 NA 0.93 17.41 0.69 4.79e-49 Menopause (age at onset); LIHC cis rs10454142 0.633 rs7559431 chr2:48591607 G/A cg15846641 chr2:48541264 FOXN2 0.48 5.83 0.3 1.31e-8 Sex hormone-binding globulin levels; LIHC cis rs7618501 0.602 rs9311446 chr3:50092226 G/A cg21467203 chr3:49911342 NA 0.42 7.39 0.37 1.11e-12 Intelligence (multi-trait analysis); LIHC cis rs4407350 1.000 rs9626478 chr22:44923619 A/G cg11695653 chr22:44894386 LDOC1L -0.37 -6.07 -0.31 3.44e-9 Intelligence (multi-trait analysis); LIHC trans rs66887589 0.592 rs62320740 chr4:120279486 C/A cg25214090 chr10:38739885 LOC399744 0.45 7.49 0.38 5.81e-13 Diastolic blood pressure; LIHC cis rs1997103 1.000 rs4947501 chr7:55407342 C/T cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs7613875 0.580 rs6808044 chr3:50136165 A/G cg24110177 chr3:50126178 RBM5 0.58 9.6 0.46 1.83e-19 Body mass index; LIHC cis rs8062405 1.000 rs4788102 chr16:28873398 G/A cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs17376456 0.569 rs10476520 chr5:93058290 A/C cg25358565 chr5:93447407 FAM172A 0.81 7.72 0.39 1.29e-13 Diabetic retinopathy; LIHC cis rs9473924 0.505 rs2817332 chr6:50848522 T/A cg14470998 chr6:50812995 TFAP2B -0.92 -10.91 -0.51 5.75e-24 Body mass index; LIHC cis rs9611565 0.546 rs5758426 chr22:42098763 T/G cg03806693 chr22:41940476 POLR3H 0.81 9.13 0.44 6.03e-18 Vitiligo; LIHC cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.42 0.49 2.87e-22 Total body bone mineral density; LIHC cis rs175714 0.845 rs175702 chr14:75971133 G/T cg01624173 chr14:75981868 NA -0.64 -10.92 -0.51 4.97e-24 Lymphocyte counts; LIHC cis rs4919694 0.572 rs7080935 chr10:104929113 C/A cg04362960 chr10:104952993 NT5C2 0.8 6.9 0.35 2.59e-11 Arsenic metabolism; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg13976253 chr1:202317780 PPP1R12B 0.4 6.14 0.32 2.34e-9 Lung function (FEV1/FVC); LIHC cis rs10744422 0.858 rs12426809 chr12:123327143 C/T cg25930673 chr12:123319894 HIP1R -0.86 -11.24 -0.52 3.86e-25 Schizophrenia; LIHC cis rs11098699 0.848 rs4619905 chr4:124132225 A/G cg09941581 chr4:124220074 SPATA5 0.3 5.72 0.3 2.29e-8 Mosquito bite size; LIHC cis rs2380220 0.808 rs2263180 chr6:95902309 G/A cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs3820068 0.532 rs72645862 chr1:15920366 A/G cg17385448 chr1:15911702 AGMAT 0.36 6.14 0.32 2.24e-9 Systolic blood pressure; LIHC cis rs8180040 0.739 rs11719306 chr3:47184182 G/A cg27129171 chr3:47204927 SETD2 0.7 12.54 0.56 6.26e-30 Colorectal cancer; LIHC cis rs875971 0.830 rs7799834 chr7:65880694 A/C cg18252515 chr7:66147081 NA -0.41 -5.9 -0.3 8.62e-9 Aortic root size; LIHC cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg18876405 chr7:65276391 NA 0.56 9.33 0.45 1.34e-18 Calcium levels; LIHC cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg10862848 chr6:42927986 GNMT -0.26 -6.28 -0.32 1.03e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs3768617 0.510 rs4651139 chr1:183091963 C/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs208520 0.690 rs851464 chr6:66839802 C/T cg07460842 chr6:66804631 NA -0.8 -8.66 -0.42 1.95e-16 Exhaled nitric oxide output; LIHC cis rs561341 0.700 rs79272796 chr17:30226974 T/C cg13647721 chr17:30228624 UTP6 0.78 8.98 0.44 1.8e-17 Hip circumference adjusted for BMI; LIHC cis rs1697139 1.000 rs1697139 chr5:66511535 A/G cg16691251 chr5:66510806 NA 0.47 6.95 0.35 1.82e-11 Breast cancer; LIHC cis rs1348850 0.837 rs4243388 chr2:178284604 T/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.85 13.46 0.59 2.05e-33 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6748734 0.901 rs6720357 chr2:241830296 A/C cg09990169 chr2:241835740 C2orf54 -0.67 -9.56 -0.46 2.34e-19 Urinary metabolites; LIHC cis rs9303280 0.901 rs12103884 chr17:38045725 C/T cg11212589 chr17:38028394 ZPBP2 0.38 7.9 0.39 3.97e-14 Self-reported allergy; LIHC cis rs4555082 0.874 rs2816606 chr14:105716034 C/T cg10792982 chr14:105748885 BRF1 0.5 6.55 0.33 2.16e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs10508774 1.000 rs72793602 chr10:32748372 A/G cg01819863 chr10:32635814 EPC1 0.65 6.07 0.31 3.41e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4819052 0.851 rs1056099 chr21:46678892 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 8.17 0.4 6.04e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1506636 1.000 rs12333705 chr7:123356062 C/T cg03229431 chr7:123269106 ASB15 -0.59 -11.97 -0.54 8.22e-28 Plateletcrit;Platelet count; LIHC cis rs8077889 0.619 rs1230399 chr17:41845403 C/T cg26893861 chr17:41843967 DUSP3 -1.07 -20.08 -0.74 8.78e-60 Triglycerides; LIHC cis rs61041384 0.661 rs4759411 chr12:123740843 C/G cg00376283 chr12:123451042 ABCB9 -0.57 -5.93 -0.31 7.43e-9 Schizophrenia; LIHC cis rs4144743 0.941 rs10438782 chr17:45323892 G/A cg18085866 chr17:45331354 ITGB3 -0.59 -8.53 -0.42 4.87e-16 Body mass index; LIHC cis rs9896933 0.830 rs12450046 chr17:80790388 G/A cg15664640 chr17:80829946 TBCD -0.56 -5.97 -0.31 5.84e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs9341808 0.529 rs9350851 chr6:81059188 A/G cg08355045 chr6:80787529 NA 0.35 6.98 0.35 1.53e-11 Sitting height ratio; LIHC cis rs55823223 0.503 rs9906971 chr17:73848477 A/G cg10935138 chr17:73851978 WBP2 0.68 9.02 0.44 1.34e-17 Psoriasis; LIHC cis rs4970988 0.640 rs7524734 chr1:150655686 C/T cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Urate levels; LIHC cis rs7098414 0.511 rs4934134 chr10:82160582 C/T cg01528321 chr10:82214614 TSPAN14 0.44 6.67 0.34 1.05e-10 Post bronchodilator FEV1; LIHC cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg00149659 chr3:10157352 C3orf10 0.67 6.73 0.34 7.32e-11 Alzheimer's disease; LIHC cis rs17384381 1.000 rs71652696 chr1:85831792 A/C cg16011679 chr1:85725395 C1orf52 0.85 8.36 0.41 1.57e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 7.37 0.37 1.29e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs7927592 0.871 rs17603185 chr11:68376241 C/T cg01657329 chr11:68192670 LRP5 -0.48 -6.21 -0.32 1.57e-9 Total body bone mineral density; LIHC cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg06634786 chr22:41940651 POLR3H 0.76 7.78 0.39 8.57e-14 Vitiligo; LIHC cis rs4423214 1.000 rs1981412 chr11:71138710 T/C cg24826892 chr11:71159390 DHCR7 0.51 6.69 0.34 9.12e-11 Vitamin D levels; LIHC cis rs7208859 0.573 rs7214313 chr17:29138596 T/C cg13385521 chr17:29058706 SUZ12P 0.81 8.01 0.4 1.77e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg12038521 chr19:2111714 AP3D1 0.41 6.08 0.31 3.26e-9 Immature fraction of reticulocytes; LIHC cis rs4141404 0.787 rs4820042 chr22:31589056 T/C cg07713946 chr22:31675144 LIMK2 -0.42 -7.38 -0.37 1.18e-12 Paclitaxel-induced neuropathy; LIHC cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -12.71 -0.57 1.46e-30 Alzheimer's disease; LIHC cis rs1707322 0.691 rs11211174 chr1:46220816 C/G cg06784218 chr1:46089804 CCDC17 0.42 7.67 0.38 1.79e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg05590025 chr7:65112418 INTS4L2 -0.66 -7.2 -0.36 3.94e-12 Diabetic kidney disease; LIHC cis rs1799949 0.930 rs34210004 chr17:41370337 A/T cg05368731 chr17:41323189 NBR1 0.66 10.91 0.51 5.37e-24 Menopause (age at onset); LIHC cis rs2839186 0.867 rs13050387 chr21:47701423 C/T cg05896524 chr21:47604654 C21orf56 0.44 6.64 0.34 1.25e-10 Testicular germ cell tumor; LIHC trans rs4566357 0.615 rs2272204 chr2:227915601 G/T cg16088116 chr21:44841560 SIK1 -0.42 -6.49 -0.33 2.93e-10 Coronary artery disease; LIHC cis rs7208859 0.673 rs73277986 chr17:29196197 C/T cg14067834 chr17:29058358 SUZ12P 0.63 6.18 0.32 1.86e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10256972 0.669 rs10229964 chr7:1051776 A/G cg07308232 chr7:1071921 C7orf50 -0.39 -6.13 -0.31 2.41e-9 Longevity;Endometriosis; LIHC cis rs826838 0.967 rs826856 chr12:39115434 G/A cg13010199 chr12:38710504 ALG10B -0.43 -6.06 -0.31 3.61e-9 Heart rate; LIHC cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg24549020 chr5:56110836 MAP3K1 0.48 6.28 0.32 1.03e-9 Initial pursuit acceleration; LIHC cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg17372223 chr3:52568218 NT5DC2 0.36 5.96 0.31 6.43e-9 Bipolar disorder; LIHC cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg18252515 chr7:66147081 NA -1.28 -14.89 -0.63 5.07e-39 Diabetic kidney disease; LIHC cis rs10504229 0.953 rs114806125 chr8:58182416 C/T cg20607798 chr8:58055168 NA 0.46 5.81 0.3 1.44e-8 Developmental language disorder (linguistic errors); LIHC cis rs2839186 1.000 rs2839181 chr21:47685939 A/G cg09417038 chr21:47716443 C21orf57 -0.49 -7.25 -0.37 2.72e-12 Testicular germ cell tumor; LIHC cis rs7552404 0.960 rs4949877 chr1:76201668 C/G cg22875332 chr1:76189707 ACADM 0.47 6.94 0.35 1.97e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2380220 0.872 rs4546494 chr6:95990626 A/C cg15832292 chr6:96025679 MANEA 0.62 7.06 0.36 9.08e-12 Behavioural disinhibition (generation interaction); LIHC cis rs11122272 0.668 rs2749712 chr1:231537751 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.84e-22 Hemoglobin concentration; LIHC cis rs61990749 0.597 rs117131659 chr14:78131126 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.53 -8.76 -0.43 9.34e-17 Fibroblast growth factor basic levels; LIHC cis rs116095464 0.558 rs9312978 chr5:221930 C/G cg22857025 chr5:266934 NA -1.63 -16.72 -0.67 2.82e-46 Breast cancer; LIHC cis rs12893668 0.572 rs11846404 chr14:104156108 C/G cg24130564 chr14:104152367 KLC1 -0.56 -9.78 -0.47 4.34e-20 Reticulocyte count; LIHC cis rs10870270 0.956 rs6557 chr10:133781449 C/T cg17892150 chr10:133769511 PPP2R2D -0.68 -12.89 -0.57 2.93e-31 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17173397 chr1:20539594 NA 0.52 7.08 0.36 8.43e-12 Lung function (FEV1/FVC); LIHC trans rs1814175 0.646 rs61904497 chr11:49883449 A/T cg03929089 chr4:120376271 NA -0.83 -15.93 -0.65 4.11e-43 Height; LIHC cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7520050 0.966 rs2275426 chr1:46487552 G/A cg03146154 chr1:46216737 IPP -0.39 -6.37 -0.33 6.04e-10 Red blood cell count;Reticulocyte count; LIHC cis rs769267 0.930 rs4808955 chr19:19552413 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.5 7.69 0.38 1.55e-13 Tonsillectomy; LIHC cis rs2251381 0.722 rs2776252 chr21:30531705 G/A cg08807101 chr21:30365312 RNF160 0.75 10.1 0.48 3.72e-21 Selective IgA deficiency; LIHC cis rs600806 0.742 rs12753439 chr1:110015519 G/A cg23091122 chr1:110024289 SYPL2 -0.44 -6.15 -0.32 2.21e-9 Intelligence (multi-trait analysis); LIHC cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.15 -0.32 2.15e-9 Colorectal cancer; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg06529453 chr1:54955046 NA 0.43 6.4 0.33 5.15e-10 Morning vs. evening chronotype; LIHC cis rs7224685 0.501 rs781848 chr17:3958105 A/C cg09695851 chr17:3907499 NA 0.68 11.57 0.53 2.39e-26 Type 2 diabetes; LIHC cis rs9522267 0.535 rs9522298 chr13:112234457 C/A cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs3741404 0.895 rs1860368 chr11:63994692 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 -0.95 -15.95 -0.65 3.32e-43 Platelet count; LIHC cis rs644799 0.710 rs10831427 chr11:95508383 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.79 12.15 0.55 1.8e-28 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs769267 0.831 rs2872878 chr19:19480521 G/C cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.02 -0.31 4.58e-9 Tonsillectomy; LIHC cis rs9858542 0.953 rs7622302 chr3:49547561 T/C cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs74417235 0.684 rs12655636 chr5:154057618 T/C cg08754654 chr5:154026448 NA 0.32 7.01 0.35 1.25e-11 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; LIHC cis rs11122272 0.735 rs2474630 chr1:231535335 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.36 0.45 1.09e-18 Hemoglobin concentration; LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.43e-23 Developmental language disorder (linguistic errors); LIHC cis rs7523273 0.606 rs2488252 chr1:207938228 C/T cg22525895 chr1:207977042 MIR29B2 0.63 10.2 0.48 1.65e-21 Schizophrenia; LIHC cis rs9911578 0.813 rs12452313 chr17:57129882 C/A cg05425664 chr17:57184151 TRIM37 0.59 8.59 0.42 3.17e-16 Intelligence (multi-trait analysis); LIHC cis rs2637266 0.783 rs864676 chr10:78509385 A/G cg18941641 chr10:78392320 NA 0.27 5.83 0.3 1.26e-8 Pulmonary function; LIHC cis rs3796352 1.000 rs13074524 chr3:52974184 A/G cg07884673 chr3:53033167 SFMBT1 0.88 6.5 0.33 2.77e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2573652 1.000 rs2727198 chr15:100513722 T/C cg09918751 chr15:100517450 ADAMTS17 -0.82 -14.98 -0.63 2.24e-39 Height; LIHC cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 9.88 0.47 2e-20 Platelet count; LIHC cis rs11864453 0.826 rs2074626 chr16:72139184 C/A cg16558253 chr16:72132732 DHX38 -0.51 -8.02 -0.4 1.75e-14 Fibrinogen levels; LIHC cis rs7572733 0.555 rs11889006 chr2:198928647 A/G cg03934865 chr2:198174659 NA 0.46 6.69 0.34 8.93e-11 Dermatomyositis; LIHC trans rs867371 0.722 rs8033050 chr15:82561989 G/A cg18393722 chr15:85113863 UBE2QP1 -0.42 -7.14 -0.36 5.77e-12 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs10876993 0.893 rs4760168 chr12:58087737 T/G cg18357645 chr12:58087776 OS9 0.54 8.58 0.42 3.45e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Bipolar disorder; LIHC cis rs1395 0.710 rs11682913 chr2:27473649 G/A cg22903471 chr2:27725779 GCKR -0.39 -5.78 -0.3 1.67e-8 Blood metabolite levels; LIHC cis rs9916302 0.808 rs12943928 chr17:37611330 G/A cg07936489 chr17:37558343 FBXL20 -0.83 -13.44 -0.59 2.27e-33 Glomerular filtration rate (creatinine); LIHC cis rs3796619 0.924 rs11940546 chr4:1072485 C/T cg27284194 chr4:1044797 NA 0.62 10.36 0.49 4.56e-22 Recombination rate (males); LIHC cis rs8103278 1.000 rs8109951 chr19:46289503 C/T cg14061069 chr19:46274453 DMPK -0.56 -8.75 -0.43 9.57e-17 Coronary artery disease; LIHC cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg20607798 chr8:58055168 NA 0.73 8.15 0.4 7.05e-15 Developmental language disorder (linguistic errors); LIHC cis rs908922 0.676 rs12116609 chr1:152497685 C/T cg23254163 chr1:152506842 NA 0.23 5.93 0.31 7.35e-9 Hair morphology; LIHC cis rs7918232 0.941 rs788220 chr10:27447205 T/C cg14442939 chr10:27389572 ANKRD26 -0.74 -7.06 -0.36 9.19e-12 Breast cancer; LIHC cis rs8180040 0.966 rs13079098 chr3:47442863 A/G cg27129171 chr3:47204927 SETD2 0.57 9.71 0.46 7.88e-20 Colorectal cancer; LIHC cis rs2851682 1.000 rs2524296 chr11:61601378 C/T cg27386326 chr11:61587980 NA 0.58 8.74 0.43 1.05e-16 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs9790314 0.812 rs2004862 chr3:161135638 C/T cg03342759 chr3:160939853 NMD3 -0.39 -5.85 -0.3 1.14e-8 Morning vs. evening chronotype; LIHC cis rs6060960 0.502 rs6057968 chr20:30082779 A/T cg13852791 chr20:30311386 BCL2L1 0.71 6.5 0.33 2.89e-10 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; LIHC cis rs9896052 0.533 rs7406173 chr17:73454563 G/A cg25649188 chr17:73499917 CASKIN2 0.43 6.7 0.34 8.81e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs4908768 0.906 rs12403339 chr1:8558292 G/A cg20416874 chr1:8611966 RERE 0.57 8.8 0.43 6.93e-17 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg12310025 chr6:25882481 NA 0.94 12.73 0.57 1.15e-30 Blood metabolite levels; LIHC cis rs17125944 0.686 rs11621275 chr14:53363316 C/G cg00686598 chr14:53173677 PSMC6 -0.82 -9.11 -0.44 6.83e-18 Alzheimer's disease (late onset); LIHC cis rs7772486 0.875 rs7761033 chr6:146356106 C/T cg05347473 chr6:146136440 FBXO30 0.37 5.95 0.31 6.49e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10876993 0.890 rs7963927 chr12:58046272 T/G cg15848620 chr12:58087721 OS9 -0.55 -7.49 -0.38 5.89e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs9527 0.571 rs12765337 chr10:104635344 G/C cg15744005 chr10:104629667 AS3MT -0.43 -9.76 -0.47 5.07e-20 Arsenic metabolism; LIHC cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg18404041 chr3:52824283 ITIH1 0.64 10.87 0.51 7.83e-24 Bipolar disorder; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg21448741 chr8:58168803 NA 0.35 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs4906332 1.000 rs78316803 chr14:103942863 A/G cg19000871 chr14:103996768 TRMT61A -0.47 -7.98 -0.4 2.26e-14 Coronary artery disease; LIHC cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg23758822 chr17:41437982 NA 0.94 17.59 0.69 8.71e-50 Menopause (age at onset); LIHC cis rs34172651 0.517 rs2303083 chr16:24835168 G/A cg00152838 chr16:24741724 TNRC6A -0.52 -5.9 -0.3 8.83e-9 Intelligence (multi-trait analysis); LIHC cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 6.15 0.32 2.22e-9 Schizophrenia; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg21747090 chr2:27597821 SNX17 -0.44 -6.47 -0.33 3.48e-10 Total body bone mineral density; LIHC cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg16145915 chr7:1198662 ZFAND2A -0.33 -7.78 -0.39 8.49e-14 Longevity;Endometriosis; LIHC cis rs9921222 0.521 rs62032884 chr16:363415 C/T cg12437481 chr16:420112 MRPL28 -0.64 -8.65 -0.42 2.08e-16 Bone mineral density (spine);Bone mineral density; LIHC cis rs4908760 0.965 rs12080583 chr1:8524877 G/A cg20416874 chr1:8611966 RERE -0.68 -14.5 -0.62 1.81e-37 Vitiligo; LIHC cis rs360798 0.512 rs4461246 chr2:63027671 C/T cg17519650 chr2:63277830 OTX1 -0.56 -8.53 -0.42 4.98e-16 Coronary artery disease; LIHC cis rs7772486 0.754 rs4896839 chr6:146019689 T/G cg13319975 chr6:146136371 FBXO30 0.41 6.74 0.34 6.59e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7917772 0.582 rs10786680 chr10:104317192 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.52 8.05 0.4 1.34e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4474465 1.000 rs7102316 chr11:78149365 C/T cg02023728 chr11:77925099 USP35 0.35 6.2 0.32 1.58e-9 Alzheimer's disease (survival time); LIHC cis rs651907 0.514 rs12636047 chr3:101434449 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.61 0.5 6.33e-23 Colorectal cancer; LIHC cis rs2281845 0.507 rs11589642 chr1:201100748 A/G cg06714761 chr1:201096289 NA -0.37 -6.44 -0.33 4.04e-10 Permanent tooth development; LIHC cis rs7044106 0.734 rs10491784 chr9:123432289 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.59 0.38 3.04e-13 Hip circumference adjusted for BMI; LIHC cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 8.8 0.43 7.08e-17 Platelet count; LIHC trans rs62103177 0.525 rs4283293 chr18:77759582 A/G cg05926928 chr17:57297772 GDPD1 -0.57 -6.45 -0.33 3.87e-10 Opioid sensitivity; LIHC cis rs7666738 0.830 rs35644814 chr4:98886111 G/C cg05340658 chr4:99064831 C4orf37 0.66 11.92 0.54 1.23e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs6754311 0.597 rs6760329 chr2:136544752 A/G cg07305463 chr2:136567211 LCT 0.34 6.29 0.32 9.56e-10 Mosquito bite size; LIHC cis rs6499255 0.951 rs61310815 chr16:69701239 A/T cg15192750 chr16:69999425 NA 0.43 6.68 0.34 9.71e-11 IgE levels; LIHC cis rs12824058 0.831 rs7299065 chr12:130809661 A/T cg26677194 chr12:130822605 PIWIL1 0.52 7.36 0.37 1.36e-12 Menopause (age at onset); LIHC cis rs9816226 0.587 rs9863591 chr3:185841624 C/G cg00760338 chr3:185826511 ETV5 -0.55 -7.27 -0.37 2.42e-12 Obesity;Body mass index; LIHC trans rs11098499 0.691 rs17009144 chr4:120270795 C/T cg25214090 chr10:38739885 LOC399744 -0.44 -7.32 -0.37 1.8e-12 Corneal astigmatism; LIHC cis rs7937682 0.924 rs875258 chr11:111530607 C/A cg09085632 chr11:111637200 PPP2R1B -1.04 -13.22 -0.58 1.56e-32 Primary sclerosing cholangitis; LIHC cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg11062466 chr8:58055876 NA 0.53 7.6 0.38 2.85e-13 Developmental language disorder (linguistic errors); LIHC cis rs611744 0.967 rs641721 chr8:109230140 G/A cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.15 -17.84 -0.69 8.72e-51 Gut microbiome composition (summer); LIHC cis rs8103278 1.000 rs9807819 chr19:46239598 C/T cg14061069 chr19:46274453 DMPK -0.58 -9.37 -0.45 1.02e-18 Coronary artery disease; LIHC cis rs12464559 0.522 rs7583060 chr2:152620943 C/A cg01189475 chr2:152685088 ARL5A 0.65 7.99 0.4 2.02e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC trans rs11098499 0.866 rs12501602 chr4:120287935 A/T cg25214090 chr10:38739885 LOC399744 0.5 8.02 0.4 1.69e-14 Corneal astigmatism; LIHC cis rs1712517 0.844 rs1163075 chr10:105021263 A/G cg05636881 chr10:105038444 INA -0.37 -5.94 -0.31 7.15e-9 Migraine; LIHC cis rs7618501 0.633 rs4688755 chr3:50064424 G/A cg21467203 chr3:49911342 NA 0.43 7.62 0.38 2.56e-13 Intelligence (multi-trait analysis); LIHC cis rs35146811 0.586 rs1076237 chr7:99585441 A/C cg22906224 chr7:99728672 NA 0.48 6.42 0.33 4.65e-10 Coronary artery disease; LIHC cis rs4820539 1.000 rs5751589 chr22:23475762 A/G cg14186256 chr22:23484241 RTDR1 -0.98 -21.68 -0.76 3.44e-66 Bone mineral density; LIHC cis rs425277 0.628 rs262668 chr1:2082602 A/G cg24578937 chr1:2090814 PRKCZ 0.32 5.94 0.31 6.94e-9 Height; LIHC cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg05368731 chr17:41323189 NBR1 0.72 12.48 0.56 9.96e-30 Menopause (age at onset); LIHC cis rs7249142 0.562 rs2314035 chr19:19284920 T/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.47 -7.88 -0.39 4.53e-14 IgG glycosylation; LIHC cis rs7000551 0.751 rs2100291 chr8:22374551 C/T cg12081754 chr8:22256438 SLC39A14 0.41 6.53 0.33 2.45e-10 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs55823223 0.702 rs3785437 chr17:73906222 G/T cg08125733 chr17:73851984 WBP2 0.89 7.95 0.39 2.81e-14 Psoriasis; LIHC cis rs3015497 0.586 rs7144714 chr14:51078585 G/A cg09863266 chr14:51125203 SAV1 -0.38 -5.99 -0.31 5.37e-9 Mean platelet volume; LIHC cis rs36051895 0.659 rs1159782 chr9:5078117 T/C cg02405213 chr9:5042618 JAK2 -0.68 -11.49 -0.53 4.71e-26 Pediatric autoimmune diseases; LIHC cis rs2439831 1.000 rs689596 chr15:43761717 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.78 0.43 7.73e-17 Lung cancer in ever smokers; LIHC cis rs79057730 0.599 rs79272827 chr7:807015 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.81 9.2 0.45 3.5e-18 Initial pursuit acceleration; LIHC cis rs7927592 0.763 rs4340059 chr11:68362433 A/G cg01657329 chr11:68192670 LRP5 -0.5 -7.39 -0.37 1.14e-12 Total body bone mineral density; LIHC cis rs9303280 0.901 rs1008723 chr17:38066267 G/T cg11212589 chr17:38028394 ZPBP2 0.33 6.93 0.35 2.14e-11 Self-reported allergy; LIHC cis rs8180040 1.000 rs553989 chr3:47400328 A/G cg27129171 chr3:47204927 SETD2 -0.66 -11.47 -0.53 5.41e-26 Colorectal cancer; LIHC cis rs2439831 0.850 rs28696802 chr15:44140395 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.33 0.41 2.02e-15 Lung cancer in ever smokers; LIHC cis rs796364 1.000 rs281785 chr2:200749566 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.73 8.56 0.42 4.01e-16 Schizophrenia; LIHC cis rs6545883 0.868 rs6545887 chr2:61828818 C/G cg14146966 chr2:61757674 XPO1 0.48 8.14 0.4 7.34e-15 Tuberculosis; LIHC cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.98 -9.75 -0.47 5.44e-20 Platelet count; LIHC cis rs13256369 0.951 rs12679360 chr8:8566269 G/T cg17143192 chr8:8559678 CLDN23 -0.68 -10.81 -0.5 1.21e-23 Obesity-related traits; LIHC cis rs7945705 0.837 rs10769981 chr11:9024460 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.37 5.76 0.3 1.83e-8 Hemoglobin concentration; LIHC cis rs2439831 0.681 rs3742971 chr15:43622916 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.74 -11.11 -0.51 1.1e-24 Lung cancer in ever smokers; LIHC cis rs3096299 0.685 rs4785568 chr16:89553707 A/G cg00750074 chr16:89608354 SPG7 -0.5 -8.11 -0.4 9.34e-15 Multiple myeloma (IgH translocation); LIHC cis rs2239547 0.657 rs2071040 chr3:52864860 A/G cg11645453 chr3:52864694 ITIH4 0.34 8.32 0.41 2.05e-15 Schizophrenia; LIHC cis rs74233809 1.000 rs10883815 chr10:104739179 T/C cg03493300 chr10:104813866 CNNM2 0.44 5.76 0.3 1.87e-8 Birth weight; LIHC cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg03264133 chr6:25882463 NA 0.58 8.24 0.41 3.73e-15 Blood metabolite levels; LIHC cis rs896854 0.552 rs2515236 chr8:95934907 A/G cg13393036 chr8:95962371 TP53INP1 0.32 6.39 0.33 5.53e-10 Type 2 diabetes; LIHC cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg11764359 chr7:65958608 NA 0.57 5.82 0.3 1.39e-8 Diabetic kidney disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg19487717 chr11:70263216 CTTN 0.42 6.23 0.32 1.41e-9 Longevity; LIHC cis rs12908161 0.959 rs12906348 chr15:85329421 A/C cg12863693 chr15:85201151 NMB 0.45 6.33 0.32 7.87e-10 Schizophrenia; LIHC cis rs6831256 1.000 rs10007119 chr4:3473066 A/G cg08741688 chr4:3415352 RGS12 -0.44 -6.88 -0.35 2.8e-11 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC cis rs1943345 0.519 rs11233504 chr11:82886525 A/G cg07047830 chr11:82868014 PCF11 0.55 9.77 0.47 4.81e-20 Obesity-related traits; LIHC cis rs7927771 0.524 rs12286721 chr11:47701528 G/T cg20307385 chr11:47447363 PSMC3 -0.7 -10.47 -0.49 1.89e-22 Subjective well-being; LIHC cis rs2163237 0.928 rs11125597 chr2:55979316 C/T cg18811423 chr2:55921094 PNPT1 -0.49 -6.81 -0.35 4.53e-11 IgG glycosylation; LIHC cis rs1538970 1.000 rs1538970 chr1:45847562 G/A cg05343316 chr1:45956843 TESK2 0.59 8.91 0.43 3.14e-17 Platelet count; LIHC cis rs57221529 0.766 rs12521988 chr5:556421 C/T cg09021430 chr5:549028 NA -0.46 -9.13 -0.44 5.9e-18 Lung disease severity in cystic fibrosis; LIHC cis rs911119 0.866 rs4346460 chr20:23569400 C/T cg16589663 chr20:23618590 CST3 0.65 6.74 0.34 6.57e-11 Chronic kidney disease; LIHC cis rs12220238 1.000 rs10824096 chr10:75937554 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs8177179 0.967 rs4287912 chr3:133437778 A/G cg24879335 chr3:133465180 TF 0.47 10.82 0.5 1.18e-23 Iron status biomarkers (transferrin levels); LIHC cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg22800045 chr5:56110881 MAP3K1 0.69 8.81 0.43 6.22e-17 Initial pursuit acceleration; LIHC cis rs67981189 0.593 rs7145285 chr14:71561474 A/G cg15816911 chr14:71606274 NA 0.42 6.73 0.34 7.31e-11 Schizophrenia; LIHC cis rs1577917 0.655 rs2758848 chr6:86347605 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.35 -6.23 -0.32 1.36e-9 Response to antipsychotic treatment; LIHC cis rs7100689 0.784 rs3120977 chr10:82075324 C/G cg00277334 chr10:82204260 NA -0.55 -6.91 -0.35 2.43e-11 Post bronchodilator FEV1; LIHC cis rs35110281 0.811 rs2838339 chr21:45075750 A/G cg01579765 chr21:45077557 HSF2BP 0.33 6.28 0.32 1.04e-9 Mean corpuscular volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14089307 chr14:69446181 ACTN1 -0.4 -6.15 -0.32 2.15e-9 Cognitive function; LIHC cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg02290350 chr8:58132656 NA 0.44 8.86 0.43 4.53e-17 Developmental language disorder (linguistic errors); LIHC cis rs3741404 0.791 rs2282491 chr11:63918373 T/C cg18225595 chr11:63971243 STIP1 0.68 10.79 0.5 1.44e-23 Platelet count; LIHC cis rs1198430 0.759 rs946267 chr1:23747703 A/T cg13183780 chr1:23809682 ASAP3 -0.38 -6.67 -0.34 1.02e-10 Total cholesterol levels; LIHC cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg07424592 chr7:64974309 NA 0.83 9.63 0.46 1.45e-19 Diabetic kidney disease; LIHC cis rs2412488 0.927 rs28414913 chr4:54339053 A/G cg22241045 chr4:54363911 LNX1 -0.42 -6.75 -0.34 6.49e-11 DNA methylation (variation); LIHC cis rs3734219 0.507 rs1887843 chr6:3354261 A/G cg18842474 chr6:3356384 SLC22A23 0.37 6.02 0.31 4.53e-9 Red cell distribution width; LIHC cis rs9467773 0.565 rs6925047 chr6:26521435 C/G cg11502198 chr6:26597334 ABT1 0.6 7.98 0.4 2.23e-14 Intelligence (multi-trait analysis); LIHC cis rs13118159 1.000 rs13118159 chr4:1365127 A/G cg16405210 chr4:1374714 KIAA1530 -0.61 -7.6 -0.38 2.85e-13 Longevity; LIHC cis rs858239 0.600 rs7788821 chr7:23133645 A/T cg23682824 chr7:23144976 KLHL7 0.4 6.08 0.31 3.27e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg11890956 chr21:40555474 PSMG1 -0.49 -7.9 -0.39 3.89e-14 Cognitive function; LIHC cis rs2607426 1.000 rs2607423 chr19:41275487 A/G cg20631044 chr19:41255890 C19orf54;SNRPA -0.49 -5.88 -0.3 9.77e-9 Blood protein levels; LIHC cis rs787274 0.543 rs1041086 chr9:115627744 C/G cg13803584 chr9:115635662 SNX30 -0.64 -7.34 -0.37 1.57e-12 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs3748682 0.861 rs28625842 chr1:38310786 G/A cg12658694 chr1:38397304 INPP5B 0.43 5.89 0.3 9.18e-9 Hypothyroidism; LIHC cis rs34779708 0.931 rs34375045 chr10:35362356 A/C cg03585969 chr10:35415529 CREM 0.85 12.92 0.57 2.35e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg06108461 chr20:60628389 TAF4 -1.0 -17.0 -0.68 2.01e-47 Body mass index; LIHC cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg02244288 chr16:89573955 SPG7 -0.3 -5.74 -0.3 2.13e-8 Multiple myeloma (IgH translocation); LIHC cis rs1348850 0.874 rs1348848 chr2:178358233 A/C cg02961200 chr2:178257176 LOC100130691;AGPS -0.88 -14.23 -0.61 2.14e-36 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10197940 0.578 rs2045025 chr2:152317531 T/C cg19508488 chr2:152266495 RIF1 0.47 6.68 0.34 9.94e-11 Lung cancer; LIHC cis rs1997103 1.000 rs2177804 chr7:55410302 G/A cg17469321 chr7:55412551 NA 0.47 7.03 0.36 1.16e-11 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2839627 0.561 rs6586248 chr21:44257812 C/T cg18192155 chr21:44258298 NA 0.4 5.99 0.31 5.27e-9 Information processing speed; LIHC cis rs2228479 0.702 rs11076621 chr16:89837927 A/G cg19635926 chr16:89946313 TCF25 0.51 6.52 0.33 2.56e-10 Skin colour saturation; LIHC cis rs7267979 0.565 rs6107060 chr20:25592476 C/G cg24626310 chr20:25276739 ABHD12;PYGB 0.42 5.91 0.3 8.22e-9 Liver enzyme levels (alkaline phosphatase); LIHC cis rs9640161 0.830 rs3757425 chr7:150067640 A/C cg10018233 chr7:150070692 REPIN1 0.7 13.19 0.58 2.05e-32 Blood protein levels;Circulating chemerin levels; LIHC cis rs12142240 0.698 rs56284503 chr1:46847127 C/G cg14993813 chr1:46806288 NSUN4 -0.65 -5.89 -0.3 9.4e-9 Menopause (age at onset); LIHC cis rs477895 1.000 rs2276014 chr11:64081445 G/A cg18225595 chr11:63971243 STIP1 0.59 5.75 0.3 1.96e-8 Mean platelet volume; LIHC cis rs6754311 0.597 rs2082729 chr2:136550109 C/T cg25344623 chr2:136566232 LCT 0.44 8.7 0.43 1.38e-16 Mosquito bite size; LIHC cis rs2832191 0.791 rs9983651 chr21:30491227 T/A cg08807101 chr21:30365312 RNF160 -0.57 -8.96 -0.44 2.14e-17 Dental caries; LIHC cis rs4665809 1.000 rs6749855 chr2:26255263 A/G cg27170947 chr2:26402098 FAM59B -0.65 -7.9 -0.39 3.96e-14 Gut microbiome composition (summer); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03209809 chr3:126422892 CHCHD6 0.45 6.26 0.32 1.18e-9 Pancreatic cancer; LIHC cis rs4722404 0.800 rs7809262 chr7:3141137 A/G cg19214707 chr7:3157722 NA -0.33 -5.98 -0.31 5.6e-9 Atopic dermatitis; LIHC cis rs2304069 0.954 rs216127 chr5:149428890 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.94 11.59 0.53 1.95e-26 HIV-1 control; LIHC cis rs75908454 1.000 rs77187354 chr6:169983808 T/C cg19338460 chr6:170058176 WDR27 -0.89 -8.08 -0.4 1.1e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg25405998 chr7:65216604 CCT6P1 -0.45 -6.75 -0.34 6.53e-11 Calcium levels; LIHC cis rs11864453 0.826 rs12448315 chr16:72147242 G/T cg01557791 chr16:72042693 DHODH -0.5 -8.09 -0.4 1.07e-14 Fibrinogen levels; LIHC cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.26 -0.61 1.61e-36 Alzheimer's disease; LIHC trans rs4478037 0.749 rs9311003 chr3:33131070 A/G cg00339104 chr7:32930089 KBTBD2 -0.44 -6.3 -0.32 9.06e-10 Major depressive disorder; LIHC cis rs6782228 0.606 rs7627549 chr3:128353079 G/A cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs2303759 0.874 rs10411630 chr19:49891314 C/A cg05022225 chr19:49866942 DKKL1;TEAD2 0.57 8.83 0.43 5.73e-17 Multiple sclerosis; LIHC cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg09177884 chr7:1199841 ZFAND2A -0.44 -6.26 -0.32 1.14e-9 Longevity;Endometriosis; LIHC cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg17971929 chr21:40555470 PSMG1 0.85 10.18 0.48 1.99e-21 Cognitive function; LIHC cis rs568617 1.000 rs693824 chr11:65654783 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.44 6.44 0.33 4.17e-10 Crohn's disease; LIHC cis rs6960043 1.000 rs6972333 chr7:15051643 G/A cg19272540 chr7:15055459 NA -0.23 -6.37 -0.33 6.17e-10 Type 2 diabetes; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg11070056 chr1:107600091 PRMT6 -0.62 -10.31 -0.49 7.01e-22 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12451471 0.637 rs12452616 chr17:78090081 A/G cg24585782 chr17:78113791 EIF4A3 0.45 6.13 0.31 2.46e-9 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs7216064 1.000 rs11869819 chr17:65868669 A/C cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs72781680 0.821 rs72796401 chr2:24180078 T/A cg08917208 chr2:24149416 ATAD2B 0.62 6.25 0.32 1.25e-9 Lymphocyte counts; LIHC cis rs898097 0.841 rs8180 chr17:80901036 C/G cg15664640 chr17:80829946 TBCD 0.66 10.52 0.49 1.33e-22 Breast cancer; LIHC cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg22633049 chr21:46681294 NA -0.37 -6.39 -0.33 5.47e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2976388 0.556 rs10956985 chr8:143818750 C/A cg24634471 chr8:143751801 JRK -0.43 -5.98 -0.31 5.51e-9 Urinary tract infection frequency; LIHC cis rs7584330 0.868 rs7569197 chr2:238383073 A/G cg14458575 chr2:238380390 NA 0.43 6.68 0.34 9.84e-11 Prostate cancer; LIHC cis rs9814567 1.000 rs4423809 chr3:134300107 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.16 0.32 2.05e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4665809 1.000 rs12475854 chr2:26267375 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.45 -0.42 8.76e-16 Gut microbiome composition (summer); LIHC cis rs17818399 0.962 rs7565274 chr2:46841861 G/T cg02822958 chr2:46747628 ATP6V1E2 0.45 6.73 0.34 7.22e-11 Height; LIHC cis rs7224685 0.906 rs9915922 chr17:4083242 T/C cg09695851 chr17:3907499 NA 0.61 8.36 0.41 1.56e-15 Type 2 diabetes; LIHC trans rs9929218 1.000 rs17772363 chr16:68788909 G/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -9.41 -0.45 7.24e-19 Colorectal cancer; LIHC cis rs4423214 0.535 rs1540129 chr11:71129523 C/G cg05163923 chr11:71159392 DHCR7 0.67 9.7 0.46 8.44e-20 Vitamin D levels; LIHC cis rs10791097 0.720 rs6590518 chr11:130733530 C/T cg12179176 chr11:130786555 SNX19 0.79 12.58 0.56 4.41e-30 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs16866061 1.000 rs17480230 chr2:225399864 G/A cg12698349 chr2:225449008 CUL3 0.81 14.18 0.61 3.16e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs2832191 0.740 rs2832177 chr21:30478353 G/A cg24692254 chr21:30365293 RNF160 -0.87 -16.24 -0.66 2.25e-44 Dental caries; LIHC cis rs7772486 0.790 rs2485632 chr6:146193228 A/G cg05347473 chr6:146136440 FBXO30 0.37 6.03 0.31 4.27e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs35146811 0.844 rs4729576 chr7:99692594 G/A cg22906224 chr7:99728672 NA 0.42 5.84 0.3 1.22e-8 Coronary artery disease; LIHC cis rs7523273 0.606 rs859706 chr1:207962270 G/A cg22525895 chr1:207977042 MIR29B2 -0.61 -9.96 -0.47 1.13e-20 Schizophrenia; LIHC cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg25072359 chr17:41440525 NA 0.38 6.06 0.31 3.67e-9 Menopause (age at onset); LIHC cis rs8180040 0.627 rs6442059 chr3:47187075 C/G cg16586182 chr3:47516702 SCAP -0.48 -8.46 -0.42 7.82e-16 Colorectal cancer; LIHC cis rs769267 0.930 rs3752151 chr19:19616026 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.51 7.65 0.38 2e-13 Tonsillectomy; LIHC cis rs4820539 1.000 rs2157710 chr22:23457486 C/T cg21100191 chr22:23484243 RTDR1 0.86 15.57 0.64 1.04e-41 Bone mineral density; LIHC cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg01017244 chr2:74357527 NA 0.66 12.1 0.55 2.78e-28 Gestational age at birth (maternal effect); LIHC cis rs796364 0.760 rs11690371 chr2:200989616 A/G cg12253985 chr2:200820533 C2orf60;C2orf47 -0.75 -8.33 -0.41 2.04e-15 Schizophrenia; LIHC cis rs7937890 0.531 rs2575828 chr11:14484192 T/C cg02886208 chr11:14281011 SPON1 -0.46 -6.5 -0.33 2.79e-10 Mitochondrial DNA levels; LIHC cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg10802521 chr3:52805072 NEK4 -0.45 -7.73 -0.39 1.2e-13 Bipolar disorder; LIHC cis rs1707322 1.000 rs11211190 chr1:46266255 C/T cg06784218 chr1:46089804 CCDC17 0.36 6.37 0.33 6.22e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs79387448 0.745 rs17027341 chr2:103136559 A/G cg09003973 chr2:102972529 NA 0.81 7.1 0.36 7.2e-12 Gut microbiota (bacterial taxa); LIHC cis rs6450176 0.951 rs255757 chr5:53309371 G/A ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.62 -0.62 6.11e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs9911578 1.000 rs7215808 chr17:56940742 G/C cg05425664 chr17:57184151 TRIM37 -0.6 -8.83 -0.43 5.53e-17 Intelligence (multi-trait analysis); LIHC cis rs7945718 0.621 rs7481252 chr11:12681682 A/G cg25843174 chr11:12811716 TEAD1 0.33 7.71 0.38 1.42e-13 Educational attainment (years of education); LIHC cis rs9640161 0.659 rs17837498 chr7:150009679 A/G cg21361702 chr7:150065534 REPIN1 0.48 6.63 0.34 1.29e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs3793683 0.928 rs2148666 chr10:134553785 A/G cg06453172 chr10:134556979 INPP5A -0.53 -7.55 -0.38 3.91e-13 Migraine; LIHC cis rs2074193 0.585 rs11183915 chr12:47770984 C/T cg09441395 chr12:48500072 SENP1;PFKM -0.43 -5.74 -0.3 2.11e-8 Migraine with aura; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01727434 chr2:152118530 RBM43 0.46 6.63 0.34 1.34e-10 Pancreatic cancer; LIHC cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg14709524 chr16:89940631 TCF25 0.55 7.17 0.36 4.72e-12 Skin colour saturation; LIHC cis rs6952808 0.564 rs73038441 chr7:2139286 T/C cg20295408 chr7:1910781 MAD1L1 -0.41 -6.1 -0.31 2.92e-9 Bipolar disorder and schizophrenia; LIHC cis rs3791556 0.661 rs3791539 chr2:240102327 C/T cg03281426 chr2:240109471 HDAC4 0.4 6.46 0.33 3.56e-10 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs769267 0.965 rs7254230 chr19:19434350 C/T cg03709012 chr19:19516395 GATAD2A -0.91 -15.52 -0.64 1.65e-41 Tonsillectomy; LIHC trans rs9388451 0.626 rs1935983 chr6:126068914 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.66 -10.88 -0.51 6.98e-24 Brugada syndrome; LIHC cis rs3740540 0.761 rs34496154 chr10:126284336 C/T cg20435097 chr10:126320824 FAM53B 0.54 7.95 0.39 2.77e-14 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs16854884 0.609 rs9872126 chr3:143683851 G/A cg06585982 chr3:143692056 C3orf58 0.48 6.78 0.34 5.41e-11 Economic and political preferences (feminism/equality); LIHC cis rs2642442 1.000 rs2642442 chr1:220973563 A/G cg04704887 chr1:220970030 MOSC1 0.45 6.08 0.31 3.18e-9 Cholesterol, total;LDL cholesterol; LIHC cis rs597539 0.652 rs584108 chr11:68630282 A/T cg04772025 chr11:68637568 NA -0.49 -6.41 -0.33 4.7e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.15 11.46 0.53 5.76e-26 Platelet count; LIHC cis rs875971 0.862 rs10261398 chr7:65750164 A/G cg18252515 chr7:66147081 NA 0.44 6.33 0.32 7.52e-10 Aortic root size; LIHC cis rs1691799 0.899 rs1177555 chr12:66727568 A/G cg16791601 chr12:66731901 HELB -0.56 -13.8 -0.6 9.24e-35 White blood cell count (basophil); LIHC cis rs68170813 0.559 rs12540475 chr7:106886295 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg08280861 chr8:58055591 NA 0.51 6.07 0.31 3.41e-9 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.623 rs56018041 chr17:29059985 G/A cg13385521 chr17:29058706 SUZ12P 0.85 8.46 0.42 8.11e-16 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10540 1.000 rs61876341 chr11:495892 C/G cg03352830 chr11:487213 PTDSS2 0.83 6.99 0.35 1.43e-11 Body mass index; LIHC cis rs6752107 0.967 rs3816234 chr2:234185999 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.54 8.24 0.41 3.62e-15 Crohn's disease;Inflammatory bowel disease; LIHC trans rs561341 1.000 rs55962687 chr17:30260369 C/T cg20587970 chr11:113659929 NA -1.36 -10.9 -0.51 5.96e-24 Hip circumference adjusted for BMI; LIHC cis rs11792861 0.962 rs3829084 chr9:111801724 C/G cg13535736 chr9:111863775 C9orf5 0.41 6.3 0.32 9.38e-10 Menarche (age at onset); LIHC cis rs208520 0.633 rs7738469 chr6:66807446 T/C cg07460842 chr6:66804631 NA -0.84 -9.33 -0.45 1.38e-18 Exhaled nitric oxide output; LIHC cis rs875971 0.895 rs6460300 chr7:65952924 A/G cg18876405 chr7:65276391 NA 0.38 6.94 0.35 1.92e-11 Aortic root size; LIHC cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg04317338 chr11:64019027 PLCB3 0.88 11.06 0.51 1.63e-24 Mean platelet volume; LIHC cis rs8062405 0.755 rs56209193 chr16:28585636 C/T cg00204512 chr16:28754710 NA 0.42 7.36 0.37 1.35e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6088580 0.634 rs6087579 chr20:32985155 A/G cg08999081 chr20:33150536 PIGU -0.67 -13.32 -0.58 6.54e-33 Glomerular filtration rate (creatinine); LIHC cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg13409248 chr3:40428643 ENTPD3 0.4 6.52 0.33 2.57e-10 Renal cell carcinoma; LIHC cis rs2932538 0.922 rs12137107 chr1:113127437 A/G cg22162597 chr1:113214053 CAPZA1 0.73 11.1 0.51 1.2e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs12980942 0.872 rs2304230 chr19:41774064 T/C cg25627403 chr19:41769009 HNRNPUL1 0.5 6.29 0.32 9.54e-10 Coronary artery disease; LIHC cis rs2075371 0.527 rs1862046 chr7:134023524 T/C cg20476274 chr7:133979776 SLC35B4 0.5 6.59 0.34 1.67e-10 Mean platelet volume; LIHC cis rs6582630 0.555 rs10880625 chr12:38526612 A/C cg26384229 chr12:38710491 ALG10B 0.95 12.37 0.56 2.58e-29 Drug-induced liver injury (flucloxacillin); LIHC cis rs1580019 0.587 rs7804457 chr7:32557981 A/G cg14728415 chr7:32535168 LSM5;AVL9 0.43 6.2 0.32 1.59e-9 Cognitive ability; LIHC cis rs7474896 0.583 rs11011346 chr10:38009483 C/T cg25427524 chr10:38739819 LOC399744 -0.5 -7.07 -0.36 8.71e-12 Obesity (extreme); LIHC cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg11494091 chr17:61959527 GH2 -0.52 -9.89 -0.47 1.95e-20 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs973252 chr1:231520802 A/G cg06096015 chr1:231504339 EGLN1 0.51 9.34 0.45 1.23e-18 Hemoglobin concentration; LIHC cis rs7937682 0.889 rs493865 chr11:111495178 A/C cg09085632 chr11:111637200 PPP2R1B -0.92 -11.2 -0.52 5.29e-25 Primary sclerosing cholangitis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg25195416 chr21:46696626 POFUT2 0.42 6.46 0.33 3.53e-10 Longevity; LIHC cis rs9457247 1.000 rs2013815 chr6:167373812 T/A cg12798992 chr6:167411361 FGFR1OP -0.6 -9.93 -0.47 1.41e-20 Crohn's disease; LIHC cis rs1385374 0.858 rs11059933 chr12:129303593 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.62 7.57 0.38 3.51e-13 Systemic lupus erythematosus; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23980294 chr4:184580643 C4orf41;RWDD4A 0.45 6.04 0.31 3.98e-9 Pancreatic cancer; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg06012509 chr6:43027269 KLC4;MRPL2 -0.52 -6.7 -0.34 8.55e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs7072216 0.763 rs7909822 chr10:100172035 A/C cg26618903 chr10:100175079 PYROXD2 -0.39 -6.24 -0.32 1.26e-9 Metabolite levels; LIHC cis rs7937682 0.855 rs521947 chr11:111492616 A/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.88e-24 Primary sclerosing cholangitis; LIHC cis rs2795502 0.882 rs2744095 chr10:43337949 A/T cg20628663 chr10:43360327 NA -0.46 -7.11 -0.36 6.9e-12 Blood protein levels; LIHC cis rs11190604 1.000 rs4919465 chr10:102221703 C/T cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.2e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2257205 0.667 rs28363312 chr17:56788293 C/A cg05425664 chr17:57184151 TRIM37 -0.6 -6.56 -0.33 2e-10 Pancreatic cancer; LIHC cis rs8062405 0.964 rs11860513 chr16:28825420 C/T cg00204512 chr16:28754710 NA 0.36 6.71 0.34 7.92e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs801193 0.967 rs34356500 chr7:66236607 G/T cg26939375 chr7:64535504 NA 0.41 6.53 0.33 2.32e-10 Aortic root size; LIHC cis rs864537 0.676 rs1773560 chr1:167421763 A/G cg22356347 chr1:167427500 CD247 -0.33 -5.77 -0.3 1.74e-8 Celiac disease or Rheumatoid arthritis;Celiac disease; LIHC cis rs7246865 0.954 rs3745348 chr19:17212410 C/T cg16202187 chr19:17186497 HAUS8;MYO9B 0.41 6.22 0.32 1.49e-9 Reticulocyte fraction of red cells; LIHC trans rs1005277 0.579 rs1740735 chr10:38497777 A/C cg23533926 chr12:111358616 MYL2 -0.35 -6.66 -0.34 1.1e-10 Extrinsic epigenetic age acceleration; LIHC cis rs1023500 1.000 rs3752591 chr22:42339516 A/G cg04733989 chr22:42467013 NAGA -0.51 -6.04 -0.31 4.03e-9 Schizophrenia; LIHC trans rs73245065 0.558 rs1506784 chr10:30909900 A/C cg21500456 chr14:21190377 NA -0.45 -6.23 -0.32 1.37e-9 Bone mineral density (femoral neck); LIHC cis rs7772486 0.875 rs2814877 chr6:146299763 C/G cg13319975 chr6:146136371 FBXO30 -0.41 -6.57 -0.33 1.87e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.620 rs1811652 chr3:47208698 C/G cg27129171 chr3:47204927 SETD2 -0.58 -9.56 -0.46 2.43e-19 Colorectal cancer; LIHC cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg07424592 chr7:64974309 NA 0.83 9.5 0.46 3.78e-19 Diabetic kidney disease; LIHC cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 6.15 0.32 2.16e-9 Schizophrenia; LIHC cis rs8180040 0.739 rs4683320 chr3:47152992 C/T cg27129171 chr3:47204927 SETD2 0.69 12.29 0.55 5.22e-29 Colorectal cancer; LIHC cis rs2380220 0.576 rs4368819 chr6:96031109 T/G cg15832292 chr6:96025679 MANEA 0.69 8.54 0.42 4.46e-16 Behavioural disinhibition (generation interaction); LIHC cis rs903552 1.000 rs34937195 chr15:102003631 C/A cg00659931 chr15:102010125 PCSK6 -0.44 -6.04 -0.31 4.03e-9 Diabetic kidney disease; LIHC cis rs6062302 0.522 rs11696202 chr20:62246292 G/C cg09650180 chr20:62225654 GMEB2 -0.38 -6.05 -0.31 3.87e-9 Glioblastoma; LIHC cis rs17106184 1.000 rs12089747 chr1:51246155 C/T cg07174182 chr1:51127561 FAF1 -0.62 -7.23 -0.36 3.17e-12 Type 2 diabetes; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg01238044 chr22:24384105 GSTT1 0.73 10.83 0.51 1.1e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.94 -10.77 -0.5 1.68e-23 Platelet count; LIHC cis rs9309473 1.000 rs11893881 chr2:73824373 T/A cg20560298 chr2:73613845 ALMS1 -0.58 -7.02 -0.36 1.18e-11 Metabolite levels; LIHC cis rs2386661 0.516 rs61832676 chr10:5646337 G/A cg17085576 chr10:5658249 NA -0.35 -6.2 -0.32 1.66e-9 Breast cancer; LIHC cis rs6450176 0.538 rs12186486 chr5:53306549 T/A ch.5.1024479R chr5:53302184 ARL15 -0.97 -17.49 -0.69 2.16e-49 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg08106661 chr6:34855635 TAF11;ANKS1A 0.42 6.32 0.32 7.98e-10 Migraine with aura; LIHC cis rs6701037 0.566 rs1014555 chr1:175134249 C/T cg00958927 chr1:175162553 KIAA0040 0.39 6.55 0.33 2.11e-10 Alcohol dependence; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07466437 chr6:8086756 EEF1E1;SCARNA27 0.45 6.04 0.31 4.05e-9 Systolic blood pressure; LIHC cis rs861318 1.000 rs855865 chr1:159028378 C/T cg11003133 chr1:159046391 AIM2 0.31 6.39 0.33 5.53e-10 Obesity-related traits; LIHC trans rs7504990 0.802 rs1110616 chr18:50385517 A/T cg08535148 chr4:26321143 RBPJ 0.5 6.19 0.32 1.71e-9 Gallbladder cancer; LIHC cis rs9910055 0.530 rs7222349 chr17:42304644 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.42 7.33 0.37 1.7e-12 Total body bone mineral density; LIHC cis rs11690935 0.885 rs7602037 chr2:172817794 G/A cg13550731 chr2:172543902 DYNC1I2 -0.8 -14.32 -0.61 9.17e-37 Schizophrenia; LIHC cis rs950169 0.840 rs2896002 chr15:84945121 A/G cg17507749 chr15:85114479 UBE2QP1 0.74 8.69 0.43 1.55e-16 Schizophrenia; LIHC cis rs1801251 0.778 rs812383 chr2:233737132 C/A cg25237894 chr2:233734115 C2orf82 -0.6 -11.93 -0.54 1.14e-27 Coronary artery disease; LIHC cis rs7927592 0.913 rs7118897 chr11:68360680 G/A cg20283391 chr11:68216788 NA -0.53 -7.98 -0.4 2.26e-14 Total body bone mineral density; LIHC cis rs7107174 0.786 rs2450134 chr11:77925778 A/G cg02023728 chr11:77925099 USP35 0.54 10.49 0.49 1.62e-22 Testicular germ cell tumor; LIHC cis rs12893668 0.543 rs12147645 chr14:104100208 T/A cg08213375 chr14:104286397 PPP1R13B 0.36 5.73 0.3 2.21e-8 Reticulocyte count; LIHC cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg07092213 chr7:1199455 ZFAND2A -0.42 -6.19 -0.32 1.76e-9 Longevity;Endometriosis; LIHC trans rs500891 0.574 rs12203860 chr6:84174401 C/T cg03017863 chr2:62115939 CCT4 0.5 6.22 0.32 1.44e-9 Platelet-derived growth factor BB levels; LIHC trans rs916888 0.773 rs199448 chr17:44809001 A/G cg13957321 chr17:43675089 NA 0.49 7.88 0.39 4.53e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs716804 0.721 rs6484152 chr11:10298452 G/A cg01453529 chr11:10209919 SBF2 -0.29 -5.86 -0.3 1.11e-8 Neuroticism; LIHC cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg27121462 chr16:89883253 FANCA 0.45 7.49 0.38 5.86e-13 Vitiligo; LIHC cis rs3806843 1.000 rs3756340 chr5:140180451 T/G cg19875535 chr5:140030758 IK 0.36 5.89 0.3 9.03e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1564271 0.528 rs2489589 chr10:26983095 A/G cg13837822 chr10:26931731 LOC731789 0.39 7.28 0.37 2.25e-12 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs765787 0.530 rs11854294 chr15:45527996 A/G cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.78 -0.3 1.71e-8 Uric acid levels; LIHC trans rs208520 0.690 rs4618506 chr6:66756889 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.75 -8.35 -0.41 1.77e-15 Exhaled nitric oxide output; LIHC cis rs6448317 0.556 rs2602738 chr4:24901114 A/G cg21108841 chr4:24914750 CCDC149 -0.47 -5.88 -0.3 9.81e-9 Heschl's gyrus morphology; LIHC cis rs11233413 1.000 rs2127361 chr11:82716518 G/T cg24227371 chr11:82718527 RAB30 0.32 7.09 0.36 7.74e-12 Economic and political preferences (feminism/equality); LIHC cis rs9814567 1.000 rs10804632 chr3:134294501 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.32 -0.55 4.26e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs796364 0.589 rs55700082 chr2:201135669 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 -0.53 -6.21 -0.32 1.52e-9 Schizophrenia; LIHC cis rs6163 0.588 rs3818708 chr10:104503584 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.47 -6.82 -0.35 4.08e-11 Waist circumference;Hip circumference; LIHC cis rs4843747 0.749 rs12102841 chr16:88072574 C/G cg06050784 chr16:88016603 BANP -0.39 -6.92 -0.35 2.2e-11 Menopause (age at onset); LIHC trans rs4843747 0.671 rs28671027 chr16:88116323 G/A cg09572067 chr16:29127029 RRN3P2 0.5 8.01 0.4 1.83e-14 Menopause (age at onset); LIHC cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg05185784 chr16:90016020 DEF8 -0.45 -5.84 -0.3 1.21e-8 Skin colour saturation; LIHC cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg13047869 chr3:10149882 C3orf24 0.52 5.99 0.31 5.35e-9 Alzheimer's disease; LIHC cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.94 8.32 0.41 2.06e-15 Platelet count; LIHC cis rs8078723 0.933 rs55846942 chr17:38164470 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -9.14 -0.44 5.58e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs6088590 0.610 rs6088461 chr20:32905161 G/T cg08999081 chr20:33150536 PIGU 0.52 7.75 0.39 1.03e-13 Coronary artery disease; LIHC cis rs4819052 0.851 rs7276828 chr21:46695039 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 11.91 0.54 1.33e-27 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6964587 0.934 rs6973792 chr7:91749798 C/A cg17063962 chr7:91808500 NA 1.0 18.74 0.71 2.13e-54 Breast cancer; LIHC cis rs79247733 0.786 rs2286442 chr22:30772686 C/T cg00101453 chr22:30685584 GATSL3 0.64 7.26 0.37 2.66e-12 Tonsillectomy; LIHC cis rs798554 0.757 rs1713919 chr7:2864706 C/A cg19717773 chr7:2847554 GNA12 -0.43 -6.63 -0.34 1.3e-10 Height; LIHC cis rs10779751 0.686 rs1148478 chr1:11174067 A/T cg08854313 chr1:11322531 MTOR 0.77 9.82 0.47 3.38e-20 Body mass index; LIHC cis rs5769707 0.521 rs6009807 chr22:50058922 A/G cg01652190 chr22:50026171 C22orf34 -0.29 -6.34 -0.32 7.24e-10 Monocyte count;Monocyte percentage of white cells; LIHC cis rs9914988 0.725 rs66531973 chr17:27125993 G/T cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs35110281 0.720 rs162392 chr21:44941406 A/G cg21573476 chr21:45109991 RRP1B -0.57 -10.29 -0.49 8.32e-22 Mean corpuscular volume; LIHC trans rs7395662 0.591 rs11039766 chr11:48488715 T/C cg15704280 chr7:45808275 SEPT13 -0.46 -6.82 -0.35 4.25e-11 HDL cholesterol; LIHC cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg04267008 chr7:1944627 MAD1L1 -0.69 -11.32 -0.52 1.83e-25 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC cis rs7945705 0.967 rs10769970 chr11:8917937 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.42 7.06 0.36 9.23e-12 Hemoglobin concentration; LIHC cis rs9768139 0.708 rs36064654 chr7:158116632 C/T cg06219351 chr7:158114137 PTPRN2 -0.21 -5.92 -0.3 8.03e-9 Calcium levels; LIHC cis rs10256972 0.521 rs7457418 chr7:1110255 C/T cg23978390 chr7:1156363 C7orf50 0.44 6.15 0.32 2.17e-9 Longevity;Endometriosis; LIHC trans rs7613875 0.600 rs2856237 chr3:50158774 A/G cg21659725 chr3:3221576 CRBN -0.53 -7.83 -0.39 6.1e-14 Body mass index; LIHC cis rs548181 0.668 rs540555 chr11:125486848 T/C cg03464685 chr11:125439445 EI24 0.86 9.46 0.46 5.31e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.2 0.55 1.17e-28 Prudent dietary pattern; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC cis rs3784262 0.904 rs4646616 chr15:58261349 G/A cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.36 -0.33 6.43e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg20887711 chr4:1340912 KIAA1530 0.45 6.01 0.31 4.84e-9 Obesity-related traits; LIHC cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg27286337 chr10:134555280 INPP5A 0.88 12.65 0.56 2.31e-30 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs3096299 0.582 rs12935119 chr16:89542874 A/T cg00750074 chr16:89608354 SPG7 -0.38 -6.03 -0.31 4.22e-9 Multiple myeloma (IgH translocation); LIHC cis rs2576037 0.526 rs1789152 chr18:44433092 G/T cg19077165 chr18:44547161 KATNAL2 -0.43 -6.56 -0.33 1.99e-10 Personality dimensions; LIHC cis rs4819052 0.851 rs2838850 chr21:46671445 G/C cg11663144 chr21:46675770 NA -0.31 -5.75 -0.3 1.98e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs780096 0.565 rs10169261 chr2:27727314 C/T cg22903471 chr2:27725779 GCKR -0.54 -9.39 -0.45 9e-19 Total body bone mineral density; LIHC cis rs6840360 0.615 rs4696266 chr4:152463421 A/G cg22705602 chr4:152727874 NA -0.32 -6.34 -0.32 7.15e-10 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg16132339 chr22:24313637 DDTL;DDT 0.7 13.25 0.58 1.28e-32 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs8064024 0.599 rs2456779 chr16:4925817 G/C cg08329684 chr16:4932620 PPL 0.35 5.93 0.31 7.23e-9 Cancer; LIHC cis rs6912958 0.559 rs451465 chr6:88043372 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.59 -11.31 -0.52 2.16e-25 Monocyte percentage of white cells; LIHC cis rs34779708 0.966 rs7077242 chr10:35481965 A/C cg03585969 chr10:35415529 CREM -0.86 -13.02 -0.58 9.04e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs926392 0.589 rs2019032 chr20:37680326 C/A cg16355469 chr20:37678765 NA 0.53 8.28 0.41 2.8e-15 Dialysis-related mortality; LIHC cis rs151997 1.000 rs27249 chr5:50232678 A/G cg06027927 chr5:50259733 NA 0.55 7.47 0.37 6.88e-13 Callous-unemotional behaviour; LIHC trans rs11098499 0.644 rs2389880 chr4:120559870 T/A cg25214090 chr10:38739885 LOC399744 0.49 7.87 0.39 4.65e-14 Corneal astigmatism; LIHC cis rs9818758 0.607 rs11706189 chr3:49210833 C/A cg00383909 chr3:49044727 WDR6 0.91 7.6 0.38 2.9e-13 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC trans rs11689435 0.925 rs12989540 chr2:218344823 T/A cg13544946 chr9:35729779 TLN1 -0.44 -6.35 -0.32 6.82e-10 Metabolite levels (MHPG); LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs35110281 0.782 rs2051407 chr21:45079245 T/C cg04455712 chr21:45112962 RRP1B 0.47 7.94 0.39 2.85e-14 Mean corpuscular volume; LIHC cis rs1059312 0.772 rs11609637 chr12:129300202 T/G cg09035930 chr12:129282057 SLC15A4 0.6 11.17 0.52 6.7e-25 Systemic lupus erythematosus; LIHC cis rs11190604 1.000 rs2295776 chr10:102295629 G/T cg07080220 chr10:102295463 HIF1AN 0.55 8.05 0.4 1.37e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6840360 0.571 rs12648420 chr4:152543434 G/C cg22705602 chr4:152727874 NA -0.34 -6.51 -0.33 2.65e-10 Intelligence (multi-trait analysis); LIHC cis rs6782228 0.628 rs7641584 chr3:128392630 G/C cg16766828 chr3:128327626 NA -0.42 -6.6 -0.34 1.61e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7208859 0.623 rs216445 chr17:28933576 A/G cg13385521 chr17:29058706 SUZ12P 0.67 6.57 0.33 1.88e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7223966 1.000 rs2665826 chr17:61944924 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.91 0.35 2.44e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9837602 0.507 rs793452 chr3:99529523 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.48 -6.71 -0.34 8.07e-11 Breast cancer; LIHC trans rs2727020 0.704 rs4144700 chr11:49370834 C/A cg15704280 chr7:45808275 SEPT13 -0.93 -17.77 -0.69 1.72e-50 Coronary artery disease; LIHC trans rs1973993 0.544 rs2800427 chr1:97002766 A/C cg10631902 chr5:14652156 NA 0.32 7.5 0.38 5.5e-13 Weight; LIHC cis rs1153858 0.887 rs28569043 chr15:45730926 A/T cg21132104 chr15:45694354 SPATA5L1 0.39 6.33 0.32 7.52e-10 Homoarginine levels; LIHC trans rs911555 0.723 rs6575982 chr14:103862681 G/A cg17675199 chr6:35436792 RPL10A -0.4 -8.19 -0.4 5.33e-15 Intelligence (multi-trait analysis); LIHC cis rs1403694 1.000 rs2651640 chr3:186438393 G/A cg12454167 chr3:186435060 KNG1 0.29 7.05 0.36 1.02e-11 Blood protein levels; LIHC cis rs826838 0.935 rs11168761 chr12:38997211 C/A cg13010199 chr12:38710504 ALG10B 0.56 6.82 0.35 4.23e-11 Heart rate; LIHC cis rs937213 0.573 rs3816900 chr15:40302243 C/T cg20255370 chr15:40268687 EIF2AK4 -0.37 -6.17 -0.32 1.88e-9 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.05 0.55 4.17e-28 Prudent dietary pattern; LIHC cis rs9905704 0.647 rs2286299 chr17:57043367 T/G cg12560992 chr17:57184187 TRIM37 0.68 9.96 0.47 1.13e-20 Testicular germ cell tumor; LIHC trans rs1814175 0.645 rs11040535 chr11:49808669 C/T cg18944383 chr4:111397179 ENPEP 0.27 6.91 0.35 2.33e-11 Height; LIHC cis rs4919694 1.000 rs74749600 chr10:104732996 T/C cg04362960 chr10:104952993 NT5C2 1.09 7.82 0.39 6.53e-14 Arsenic metabolism; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06697094 chr17:54911185 DGKE -0.41 -6.18 -0.32 1.8e-9 Cognitive function; LIHC cis rs2625529 0.824 rs12593134 chr15:72303007 G/C cg16672083 chr15:72433130 SENP8 -0.3 -5.77 -0.3 1.78e-8 Red blood cell count; LIHC cis rs738322 0.555 rs731821 chr22:38559448 C/A cg25457927 chr22:38595422 NA -0.39 -9.44 -0.45 6.09e-19 Cutaneous nevi; LIHC cis rs919433 0.889 rs788004 chr2:198219032 C/T cg10820045 chr2:198174542 NA 0.53 8.86 0.43 4.52e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs16828019 0.929 rs2363805 chr1:41719434 G/T cg03962019 chr1:41807865 NA 0.5 7.19 0.36 4.21e-12 Intelligence (multi-trait analysis); LIHC cis rs34779708 0.733 rs60553075 chr10:35542462 T/A cg03585969 chr10:35415529 CREM 0.76 11.02 0.51 2.18e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10845606 0.581 rs10772592 chr12:12835874 A/G cg04607235 chr12:12878440 APOLD1 -0.47 -6.44 -0.33 4.1e-10 Systemic lupus erythematosus; LIHC cis rs6570726 0.967 rs1396648 chr6:145785248 C/A cg23711669 chr6:146136114 FBXO30 -0.46 -7.83 -0.39 6.03e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs1506636 1.000 rs615410 chr7:123437765 T/C cg03229431 chr7:123269106 ASB15 0.51 9.3 0.45 1.72e-18 Plateletcrit;Platelet count; LIHC cis rs4727027 0.745 rs10952801 chr7:148864757 T/C cg23583168 chr7:148888333 NA -0.74 -10.37 -0.49 4.37e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs10876993 0.928 rs1678540 chr12:58065002 A/G cg15848620 chr12:58087721 OS9 -0.56 -7.71 -0.38 1.43e-13 Celiac disease or Rheumatoid arthritis; LIHC cis rs8084351 0.577 rs12966225 chr18:50658497 C/A cg24270629 chr18:50823537 DCC -0.44 -6.42 -0.33 4.55e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2404602 0.684 rs1011084 chr15:77007480 C/G cg23625390 chr15:77176239 SCAPER -0.54 -8.93 -0.43 2.6e-17 Blood metabolite levels; LIHC cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg13699009 chr12:122356056 WDR66 -0.56 -9.95 -0.47 1.16e-20 Mean corpuscular volume; LIHC cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.72 -0.57 1.29e-30 Alzheimer's disease; LIHC cis rs7520050 0.778 rs2088102 chr1:46032974 T/C cg03146154 chr1:46216737 IPP -0.47 -7.51 -0.38 5.17e-13 Red blood cell count;Reticulocyte count; LIHC cis rs600806 0.888 rs4970749 chr1:109873573 G/A cg16275483 chr1:110013120 SYPL2 -0.5 -6.27 -0.32 1.08e-9 Intelligence (multi-trait analysis); LIHC cis rs1059312 0.966 rs35907548 chr12:129282180 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.72 -14.46 -0.62 2.58e-37 Systemic lupus erythematosus; LIHC cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg13047869 chr3:10149882 C3orf24 0.51 5.88 0.3 9.55e-9 Alzheimer's disease; LIHC cis rs10911363 0.592 rs2782411 chr1:183476929 G/A cg09173681 chr1:183549694 NCF2 0.54 9.41 0.45 7.61e-19 Systemic lupus erythematosus; LIHC cis rs2153535 0.580 rs6905242 chr6:8471799 A/C cg07606381 chr6:8435919 SLC35B3 0.81 12.08 0.55 3.09e-28 Motion sickness; LIHC cis rs858239 0.601 rs929508 chr7:23166709 C/A cg23682824 chr7:23144976 KLHL7 0.45 6.68 0.34 9.63e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs6964587 0.782 rs13221571 chr7:91500236 C/T cg17063962 chr7:91808500 NA -0.95 -18.19 -0.7 3.36e-52 Breast cancer; LIHC cis rs7534824 0.543 rs10493940 chr1:101377845 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.63 7.16 0.36 4.93e-12 Refractive astigmatism; LIHC cis rs2067615 0.560 rs10431462 chr12:107106546 G/A cg15890332 chr12:107067104 RFX4 0.25 5.96 0.31 6.18e-9 Heart rate; LIHC cis rs11792861 0.926 rs2271878 chr9:111868885 G/A cg05043794 chr9:111880884 C9orf5 -0.31 -7.24 -0.36 3.07e-12 Menarche (age at onset); LIHC cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg16405210 chr4:1374714 KIAA1530 -0.41 -6.11 -0.31 2.73e-9 Obesity-related traits; LIHC cis rs2439831 0.850 rs28413704 chr15:44148427 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.65 0.42 2.09e-16 Lung cancer in ever smokers; LIHC cis rs875971 0.965 rs7794930 chr7:65778546 A/C cg11764359 chr7:65958608 NA -0.91 -16.91 -0.67 4.65e-47 Aortic root size; LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg14709524 chr16:89940631 TCF25 0.51 6.87 0.35 3.06e-11 Skin colour saturation; LIHC cis rs8180040 0.764 rs2132173 chr3:47247060 C/T cg16586182 chr3:47516702 SCAP 0.51 9.27 0.45 2.08e-18 Colorectal cancer; LIHC cis rs13161895 1.000 rs17079966 chr5:179443190 G/T cg06664874 chr5:179499304 RNF130 0.58 7.04 0.36 1.03e-11 LDL cholesterol; LIHC cis rs611744 0.870 rs672243 chr8:109098742 G/A cg21045802 chr8:109455806 TTC35 0.49 8.58 0.42 3.25e-16 Dupuytren's disease; LIHC cis rs28374715 0.681 rs7162231 chr15:41591859 G/A cg18705301 chr15:41695430 NDUFAF1 -1.21 -17.21 -0.68 2.9e-48 Ulcerative colitis; LIHC cis rs798554 0.683 rs1182155 chr7:2902890 C/G cg04166393 chr7:2884313 GNA12 0.47 7.15 0.36 5.27e-12 Height; LIHC cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.47 6.61 0.34 1.46e-10 Schizophrenia; LIHC cis rs9768139 0.708 rs896780 chr7:158113972 C/T cg06219351 chr7:158114137 PTPRN2 -0.2 -5.72 -0.3 2.36e-8 Calcium levels; LIHC cis rs36051895 0.589 rs2224571 chr9:5196253 A/C cg02405213 chr9:5042618 JAK2 -0.69 -11.57 -0.53 2.34e-26 Pediatric autoimmune diseases; LIHC cis rs12497850 0.931 rs3774628 chr3:48801840 C/T cg06212747 chr3:49208901 KLHDC8B 0.56 7.32 0.37 1.8e-12 Parkinson's disease; LIHC trans rs11098499 0.575 rs907205 chr4:120238664 G/C cg25214090 chr10:38739885 LOC399744 0.53 8.54 0.42 4.49e-16 Corneal astigmatism; LIHC cis rs9733 0.596 rs72702557 chr1:150680130 A/G cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs425535 0.619 rs8180167 chr4:74833373 A/T cg02530824 chr4:74847766 PF4 -0.36 -5.9 -0.3 8.81e-9 Blood protein levels; LIHC cis rs6674176 0.628 rs4660759 chr1:44432500 C/G cg12908607 chr1:44402522 ARTN -0.5 -8.45 -0.42 8.77e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4665809 1.000 rs10202478 chr2:26276049 T/C cg04944784 chr2:26401820 FAM59B -0.67 -8.4 -0.41 1.24e-15 Gut microbiome composition (summer); LIHC cis rs4474465 0.790 rs4544031 chr11:78265403 G/C cg27205649 chr11:78285834 NARS2 0.41 6.41 0.33 4.72e-10 Alzheimer's disease (survival time); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04250904 chr19:12623422 ZNF709 0.41 6.05 0.31 3.77e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1005277 0.579 rs1614236 chr10:38502996 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.24 -0.32 1.28e-9 Extrinsic epigenetic age acceleration; LIHC cis rs10911251 0.546 rs20560 chr1:183105534 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.37 0.49 4.44e-22 Colorectal cancer; LIHC trans rs11148252 0.875 rs4884452 chr13:52949784 C/T cg18335740 chr13:41363409 SLC25A15 -0.4 -6.95 -0.35 1.89e-11 Lewy body disease; LIHC trans rs7726839 0.540 rs3762951 chr5:662613 C/G cg25482853 chr8:67687455 SGK3 0.6 6.07 0.31 3.4e-9 Obesity-related traits; LIHC cis rs240764 0.658 rs1039030 chr6:101198707 G/A cg09795085 chr6:101329169 ASCC3 -0.45 -6.68 -0.34 9.69e-11 Neuroticism; LIHC cis rs796364 1.000 rs281783 chr2:200751582 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.77 8.92 0.43 2.83e-17 Schizophrenia; LIHC cis rs7074356 0.915 rs17617970 chr10:82206892 A/G cg00277334 chr10:82204260 NA -0.68 -5.82 -0.3 1.36e-8 Borderline personality disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04212729 chr14:65171037 PLEKHG3 0.44 6.17 0.32 1.92e-9 Pancreatic cancer; LIHC cis rs2522056 0.808 rs2706373 chr5:131804256 C/T cg24060327 chr5:131705240 SLC22A5 0.55 7.44 0.37 8.01e-13 Lymphocyte counts;Fibrinogen; LIHC cis rs5753618 0.561 rs4141404 chr22:31675185 A/C cg22777020 chr22:31556080 RNF185 -0.56 -6.42 -0.33 4.61e-10 Colorectal cancer; LIHC cis rs769267 0.896 rs2315610 chr19:19597240 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.9 0.39 3.84e-14 Tonsillectomy; LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg06453172 chr10:134556979 INPP5A -0.64 -8.36 -0.41 1.64e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs13064411 0.696 rs6799610 chr3:113248748 A/C cg18753928 chr3:113234510 CCDC52 0.43 6.2 0.32 1.61e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs17384381 0.859 rs12130591 chr1:85904985 C/T cg16011679 chr1:85725395 C1orf52 0.78 8.58 0.42 3.27e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs6570726 0.577 rs867056 chr6:145784805 A/C cg23711669 chr6:146136114 FBXO30 -0.62 -8.98 -0.44 1.83e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs8081395 0.741 rs1292053 chr17:57963537 C/T cg13753209 chr17:57696993 CLTC -0.37 -5.79 -0.3 1.61e-8 White blood cell count; LIHC trans rs7246657 0.943 rs7246993 chr19:37890154 C/T cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs7903847 0.620 rs17112676 chr10:99122288 G/A cg08345082 chr10:99160200 RRP12 -0.36 -5.99 -0.31 5.38e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs9457247 0.967 rs1590257 chr6:167377782 G/T cg23791538 chr6:167370224 RNASET2 0.69 11.76 0.54 4.7e-27 Crohn's disease; LIHC trans rs6489882 0.703 rs4767029 chr12:113359318 G/A cg10175203 chr3:128143634 NA 0.39 6.37 0.33 6e-10 Chronic lymphocytic leukemia; LIHC cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs6964587 0.633 rs13231620 chr7:91507859 G/A cg17063962 chr7:91808500 NA -0.92 -14.33 -0.61 8.4e-37 Breast cancer; LIHC cis rs7044106 0.734 rs10491784 chr9:123432289 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.67 10.73 0.5 2.46e-23 Hip circumference adjusted for BMI; LIHC cis rs738321 0.790 rs4820317 chr22:38543287 T/C cg25457927 chr22:38595422 NA -0.32 -7.1 -0.36 7.42e-12 Breast cancer; LIHC cis rs3741404 0.791 rs7112960 chr11:63907079 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.95 16.02 0.65 1.68e-43 Platelet count; LIHC cis rs9640161 0.789 rs28432021 chr7:150046235 G/C cg27494647 chr7:150038898 RARRES2 0.36 6.81 0.35 4.4e-11 Blood protein levels;Circulating chemerin levels; LIHC trans rs1005277 0.541 rs2472177 chr10:38384015 T/G cg17830980 chr10:43048298 ZNF37B -0.53 -10.74 -0.5 2.25e-23 Extrinsic epigenetic age acceleration; LIHC cis rs4843747 0.573 rs7499959 chr16:88110422 C/G cg00677901 chr16:88017247 BANP 0.47 7.27 0.37 2.54e-12 Menopause (age at onset); LIHC cis rs651907 0.535 rs13094753 chr3:101525082 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg25894440 chr7:65020034 NA -0.52 -6.1 -0.31 2.85e-9 Diabetic kidney disease; LIHC cis rs2607426 0.681 rs2545777 chr19:41287809 C/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.54 -6.18 -0.32 1.77e-9 Blood protein levels; LIHC trans rs867371 1.000 rs13380317 chr15:82506790 A/G cg18393722 chr15:85113863 UBE2QP1 0.41 6.84 0.35 3.61e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC cis rs11055008 0.620 rs2111941 chr12:12829404 A/T cg09462578 chr12:12878428 APOLD1 0.49 7.76 0.39 1.01e-13 Pulse pressure; LIHC cis rs11971779 0.585 rs3922848 chr7:139046210 T/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2274273 1.000 rs66871576 chr14:55629050 C/T cg01864836 chr14:55583639 NA -0.36 -6.09 -0.31 3.02e-9 Protein biomarker; LIHC trans rs1493916 0.748 rs2040203 chr18:31307420 G/T cg27147174 chr7:100797783 AP1S1 -0.46 -6.55 -0.33 2.08e-10 Life satisfaction; LIHC cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg21448741 chr8:58168803 NA 0.35 6.55 0.33 2.1e-10 Developmental language disorder (linguistic errors); LIHC cis rs2051211 1.000 rs17037804 chr3:38559215 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.47 -5.99 -0.31 5.19e-9 QRS duration; LIHC trans rs7246657 0.941 rs12982333 chr19:37794724 A/G cg10208301 chr11:6592745 DNHD1 0.48 6.35 0.32 6.68e-10 Coronary artery calcification; LIHC cis rs35306767 0.903 rs12260800 chr10:927933 T/C cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg07636037 chr3:49044803 WDR6 -0.75 -12.93 -0.57 1.99e-31 Menarche (age at onset); LIHC cis rs10876993 0.749 rs703832 chr12:58024626 G/C cg15848620 chr12:58087721 OS9 -0.51 -6.59 -0.34 1.62e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs1371867 0.846 rs1660345 chr8:101322762 C/A cg06636551 chr8:101224915 SPAG1 -0.49 -8.96 -0.44 2.06e-17 Atrioventricular conduction; LIHC cis rs9814567 1.000 rs7637227 chr3:134244155 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.09 -0.55 2.94e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2303759 0.709 rs8102574 chr19:49828897 A/G cg22590775 chr19:49891494 CCDC155 0.48 7.62 0.38 2.51e-13 Multiple sclerosis; LIHC cis rs7829975 0.567 rs6601273 chr8:8796519 T/G cg06636001 chr8:8085503 FLJ10661 -0.42 -6.58 -0.34 1.77e-10 Mood instability; LIHC cis rs9309473 0.898 rs10170786 chr2:73812988 C/T cg20560298 chr2:73613845 ALMS1 -0.55 -6.86 -0.35 3.16e-11 Metabolite levels; LIHC cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.55 -7.72 -0.39 1.34e-13 Lymphocyte counts; LIHC cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.53 -0.38 4.56e-13 Bipolar disorder; LIHC cis rs11122272 0.701 rs2749702 chr1:231523808 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs9916302 0.851 rs12947620 chr17:37605364 T/C cg03013999 chr17:37608204 MED1 0.35 5.89 0.3 9.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs1580019 0.844 rs1037322 chr7:32501857 C/T cg07520158 chr7:32535189 LSM5;AVL9 0.5 6.71 0.34 7.96e-11 Cognitive ability; LIHC cis rs7072216 0.727 rs942807 chr10:100168219 G/A cg26618903 chr10:100175079 PYROXD2 -0.39 -6.22 -0.32 1.42e-9 Metabolite levels; LIHC cis rs990171 0.506 rs4141631 chr2:102757216 A/G cg22835712 chr2:102737379 NA 0.54 8.57 0.42 3.74e-16 Lymphocyte counts; LIHC cis rs116095464 0.558 rs6555058 chr5:226376 C/T cg22496380 chr5:211416 CCDC127 0.95 9.54 0.46 2.8e-19 Breast cancer; LIHC cis rs753955 0.592 rs7325382 chr13:24350093 T/C cg25267304 chr13:24462978 PCOTH;MIPEP -0.33 -5.86 -0.3 1.1e-8 Lung cancer; LIHC cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg25894440 chr7:65020034 NA -0.55 -6.38 -0.33 5.85e-10 Diabetic kidney disease; LIHC cis rs2574704 1.000 rs2616561 chr3:11652417 G/A cg15876825 chr3:11651881 VGLL4 0.5 8.2 0.41 4.88e-15 Body mass index; LIHC cis rs2522056 1.000 rs11242113 chr5:131777234 G/A cg24060327 chr5:131705240 SLC22A5 0.6 8.32 0.41 2.15e-15 Lymphocyte counts;Fibrinogen; LIHC cis rs3736594 0.513 rs62138966 chr2:27819172 G/A cg27432699 chr2:27873401 GPN1 0.45 6.57 0.33 1.87e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs9394841 0.620 rs9462746 chr6:41816279 T/A cg08135965 chr6:41755394 TOMM6 0.44 5.91 0.3 8.33e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs11229555 0.874 rs11601687 chr11:58338628 T/C cg15696309 chr11:58395628 NA -0.71 -8.73 -0.43 1.11e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs72781680 1.000 rs55773155 chr2:24255081 A/G cg08917208 chr2:24149416 ATAD2B 0.81 6.13 0.31 2.38e-9 Lymphocyte counts; LIHC cis rs748404 0.697 rs524547 chr15:43551023 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.48 0.42 6.71e-16 Lung cancer; LIHC cis rs7789940 1.000 rs73140069 chr7:75986790 T/A cg10167463 chr7:75959203 YWHAG -0.43 -6.84 -0.35 3.56e-11 Multiple sclerosis; LIHC cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg20818283 chr2:191399100 TMEM194B 0.46 6.33 0.32 7.87e-10 Pulse pressure; LIHC cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg04267008 chr7:1944627 MAD1L1 -0.68 -11.0 -0.51 2.73e-24 Bipolar disorder and schizophrenia; LIHC cis rs4478037 0.822 rs9825335 chr3:33123292 A/C cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.04 -0.36 1.05e-11 Major depressive disorder; LIHC cis rs992157 1.000 rs736730 chr2:219120255 C/T cg00012203 chr2:219082015 ARPC2 0.91 15.08 0.63 9.78e-40 Colorectal cancer; LIHC cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg26531700 chr6:26746687 NA 0.4 6.6 0.34 1.56e-10 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg00684032 chr4:1343700 KIAA1530 0.52 7.59 0.38 3.01e-13 Obesity-related traits; LIHC cis rs769267 0.931 rs2965197 chr19:19470910 C/T cg15052019 chr19:19431593 KIAA0892;SF4 -0.42 -5.96 -0.31 6.2e-9 Tonsillectomy; LIHC cis rs244293 0.801 rs2541241 chr17:53072993 A/C cg19360675 chr17:53046073 COX11;STXBP4 0.48 7.24 0.36 3.02e-12 Menarche (age at onset); LIHC cis rs1816752 0.905 rs4769352 chr13:25000375 G/A cg02811702 chr13:24901961 NA 0.24 6.01 0.31 4.69e-9 Obesity-related traits; LIHC cis rs12477438 0.765 rs12612688 chr2:99613091 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.7 -10.32 -0.49 6.59e-22 Chronic sinus infection; LIHC cis rs7520050 0.966 rs12410071 chr1:46358886 T/C cg03146154 chr1:46216737 IPP -0.39 -6.38 -0.33 5.75e-10 Red blood cell count;Reticulocyte count; LIHC trans rs3749855 0.679 rs13217635 chr6:17265491 A/G cg00118684 chr18:13726609 RNMT;C18orf19 -0.61 -6.08 -0.31 3.12e-9 Glucose homeostasis traits; LIHC trans rs801193 0.967 rs2707849 chr7:66152712 T/C cg26939375 chr7:64535504 NA 0.43 6.84 0.35 3.64e-11 Aortic root size; LIHC cis rs8067545 0.611 rs2703803 chr17:20107069 G/T cg13482628 chr17:19912719 NA -0.43 -7.0 -0.35 1.33e-11 Schizophrenia; LIHC cis rs921968 0.541 rs664514 chr2:219329819 A/G cg02176678 chr2:219576539 TTLL4 0.55 7.72 0.39 1.27e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg03264133 chr6:25882463 NA -0.61 -7.76 -0.39 1.02e-13 Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04294563 chr19:7694202 LOC100131801;XAB2 0.41 6.29 0.32 9.43e-10 Cognitive function; LIHC cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg11663144 chr21:46675770 NA -0.34 -6.25 -0.32 1.23e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs5769765 0.773 rs9616378 chr22:50311973 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs9394841 0.692 rs9381095 chr6:41806708 T/A cg08135965 chr6:41755394 TOMM6 0.46 6.13 0.31 2.41e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg25204440 chr1:209979598 IRF6 -0.52 -8.03 -0.4 1.57e-14 Cleft lip with or without cleft palate; LIHC trans rs7615952 0.932 rs9841157 chr3:125635655 C/A cg07211511 chr3:129823064 LOC729375 -0.86 -10.47 -0.49 2.03e-22 Blood pressure (smoking interaction); LIHC cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9534288 0.830 rs2897027 chr13:46636235 A/G cg15192986 chr13:46630673 CPB2 -0.59 -8.44 -0.42 9.34e-16 Blood protein levels; LIHC cis rs2073300 1.000 rs115730610 chr20:23442621 G/A cg12062639 chr20:23401060 NAPB 0.84 9.86 0.47 2.44e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs5769765 0.908 rs138880 chr22:50218611 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.71 -8.64 -0.42 2.19e-16 Schizophrenia; LIHC cis rs1865760 0.508 rs9379820 chr6:26049924 T/C cg18357526 chr6:26021779 HIST1H4A 0.48 7.06 0.36 9.55e-12 Height; LIHC cis rs929354 0.742 rs7806775 chr7:156947199 A/G cg17757837 chr7:157058334 UBE3C 0.72 11.77 0.54 4.51e-27 Body mass index; LIHC cis rs748404 0.578 rs576557 chr15:43597737 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.57 10.26 0.49 1.04e-21 Lung cancer; LIHC cis rs11190604 1.000 rs3750719 chr10:102248950 C/G cg07080220 chr10:102295463 HIF1AN 0.53 7.42 0.37 9.22e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs11992162 1.000 rs7460395 chr8:11835375 C/T cg00873037 chr8:11626984 NEIL2 -0.47 -5.73 -0.3 2.23e-8 Monocyte count; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg00606472 chr2:128615778 POLR2D -0.55 -6.27 -0.32 1.12e-9 Systolic blood pressure; LIHC cis rs9560113 1.000 rs9555807 chr13:112179965 C/T cg14154082 chr13:112174009 NA 0.29 6.2 0.32 1.67e-9 Menarche (age at onset); LIHC cis rs4808199 1.000 rs12972397 chr19:19562349 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.42 5.87 0.3 1.01e-8 Nonalcoholic fatty liver disease; LIHC cis rs1538970 0.781 rs713358 chr1:45988267 C/G cg05343316 chr1:45956843 TESK2 0.62 8.74 0.43 1.1e-16 Platelet count; LIHC cis rs11229555 0.874 rs11229512 chr11:58286105 T/C cg15696309 chr11:58395628 NA -0.72 -8.66 -0.42 1.95e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs9549367 0.789 rs9604040 chr13:113910611 A/G cg00898013 chr13:113819073 PROZ 0.35 6.4 0.33 5.26e-10 Platelet distribution width; LIHC cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg01017244 chr2:74357527 NA 0.63 11.21 0.52 4.6e-25 Gestational age at birth (maternal effect); LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg12419862 chr22:24373484 LOC391322 0.96 16.63 0.67 6.29e-46 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7224737 1.000 rs11079034 chr17:40288890 G/A cg02450064 chr17:40260053 DHX58 -0.29 -6.09 -0.31 3.08e-9 Fibrinogen levels; LIHC cis rs74233809 1.000 rs12413409 chr10:104719096 C/T cg03493300 chr10:104813866 CNNM2 0.44 5.91 0.3 8.33e-9 Birth weight; LIHC cis rs2033711 0.870 rs4801270 chr19:58932762 C/A cg26874164 chr19:58962979 ZNF324B 0.44 6.1 0.31 2.82e-9 Uric acid clearance; LIHC cis rs7188697 0.922 rs37055 chr16:58560775 C/T cg02549819 chr16:58548995 SETD6 -0.46 -7.2 -0.36 3.92e-12 QT interval; LIHC cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.99 0.31 5.4e-9 Menopause (age at onset); LIHC cis rs7116495 0.609 rs73543643 chr11:71835596 C/T cg26138937 chr11:71823887 C11orf51 1.32 10.9 0.51 6.21e-24 Severe influenza A (H1N1) infection; LIHC cis rs317689 0.690 rs10878946 chr12:69642315 C/T cg14784868 chr12:69753453 YEATS4 0.51 7.12 0.36 6.37e-12 Response to diuretic therapy; LIHC cis rs7100689 0.622 rs1340379 chr10:82121455 G/A cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs910316 0.763 rs175042 chr14:75470833 A/T cg11812906 chr14:75593930 NEK9 -0.74 -13.8 -0.6 1e-34 Height; LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.45 -6.54 -0.33 2.22e-10 Height; LIHC cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.54 7.57 0.38 3.43e-13 Bipolar disorder; LIHC cis rs6570726 0.791 rs11155432 chr6:145898761 T/C cg05347473 chr6:146136440 FBXO30 0.38 5.89 0.3 9.44e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.55 -7.76 -0.39 9.71e-14 Lymphocyte counts; LIHC cis rs9918079 0.560 rs12651550 chr4:15641018 G/C cg21123203 chr4:15471301 CC2D2A -0.45 -7.26 -0.37 2.6e-12 Obesity-related traits; LIHC cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg01788221 chr16:89496183 ANKRD11 0.37 5.99 0.31 5.27e-9 Multiple myeloma (IgH translocation); LIHC cis rs6138458 1.000 rs2387362 chr20:24899906 C/T cg26195577 chr20:24973756 C20orf3 -1.09 -13.71 -0.6 2.13e-34 Blood protein levels; LIHC cis rs78456975 1.000 rs13414537 chr2:1556330 C/T cg01028140 chr2:1542097 TPO -0.55 -6.57 -0.33 1.87e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1559088 0.895 rs13345542 chr19:33586739 G/C cg27124370 chr19:33622961 WDR88 0.52 8.24 0.41 3.73e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1865760 0.622 rs9295685 chr6:26071725 G/C cg17691542 chr6:26056736 HIST1H1C 0.42 6.0 0.31 5.06e-9 Height; LIHC cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg12386194 chr3:101231763 SENP7 0.47 7.03 0.36 1.1e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg06873352 chr17:61820015 STRADA 0.6 9.31 0.45 1.59e-18 Height; LIHC cis rs861020 0.771 rs126280 chr1:210019824 A/G cg05527609 chr1:210001259 C1orf107 0.98 16.03 0.65 1.63e-43 Orofacial clefts; LIHC cis rs12594515 0.967 rs71405295 chr15:45988921 T/C cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.8e-12 Waist circumference;Weight; LIHC cis rs796364 1.000 rs10178177 chr2:200829993 G/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.76 9.16 0.44 4.98e-18 Schizophrenia; LIHC cis rs3099143 1.000 rs901008 chr15:77097018 C/A cg21673338 chr15:77095150 SCAPER -0.51 -7.68 -0.38 1.67e-13 Recalcitrant atopic dermatitis; LIHC cis rs11690935 0.959 rs35391289 chr2:172634983 A/C cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.67 -0.69 4.31e-50 Schizophrenia; LIHC cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg21724239 chr8:58056113 NA 0.55 7.01 0.35 1.29e-11 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg18357526 chr6:26021779 HIST1H4A 0.58 8.04 0.4 1.49e-14 Blood metabolite levels; LIHC cis rs7520050 0.966 rs12564541 chr1:46380237 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.6e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1707322 0.752 rs28545085 chr1:46201950 G/A cg03146154 chr1:46216737 IPP 0.58 9.64 0.46 1.35e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1814175 0.565 rs4881721 chr11:49761851 G/A cg15704280 chr7:45808275 SEPT13 -0.7 -12.19 -0.55 1.24e-28 Height; LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg00656387 chr3:40428638 ENTPD3 0.5 8.41 0.41 1.13e-15 Renal cell carcinoma; LIHC cis rs225245 0.817 rs225273 chr17:33970935 A/T cg05299278 chr17:33885742 SLFN14 0.23 6.27 0.32 1.11e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs7508 0.511 rs438818 chr8:17899561 A/G cg01800426 chr8:17659068 MTUS1 -0.44 -7.11 -0.36 6.83e-12 Atrial fibrillation; LIHC cis rs8180040 0.627 rs6442059 chr3:47187075 C/G cg27129171 chr3:47204927 SETD2 0.58 9.54 0.46 2.83e-19 Colorectal cancer; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg15684290 chr8:6263623 MCPH1 0.58 6.05 0.31 3.8e-9 Musician's dystonia; LIHC cis rs4631830 0.720 rs2611475 chr10:51503178 G/A cg16070123 chr10:51489643 NA -0.38 -6.03 -0.31 4.34e-9 Prostate-specific antigen levels; LIHC cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg04944784 chr2:26401820 FAM59B -0.77 -9.44 -0.45 5.9e-19 Gut microbiome composition (summer); LIHC cis rs17253792 0.659 rs34330219 chr14:56017375 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg23283495 chr1:209979779 IRF6 0.45 7.26 0.37 2.62e-12 Cleft lip with or without cleft palate; LIHC cis rs11599315 1.000 rs11599315 chr10:1343017 C/T cg09624528 chr10:1369823 ADARB2 0.34 6.55 0.33 2.08e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs644799 0.710 rs12272061 chr11:95524067 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.25 0.58 1.27e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs68170813 0.559 rs75672288 chr7:107031549 G/C cg02696742 chr7:106810147 HBP1 -0.5 -5.73 -0.3 2.24e-8 Coronary artery disease; LIHC cis rs10744422 1.000 rs7309225 chr12:123288439 A/G cg25930673 chr12:123319894 HIP1R -0.85 -10.22 -0.48 1.39e-21 Schizophrenia; LIHC cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg06634786 chr22:41940651 POLR3H 0.68 7.55 0.38 3.88e-13 Vitiligo; LIHC trans rs1704198 1.000 rs2664688 chr1:213897415 C/T cg02442787 chr4:139230014 NA 0.41 6.24 0.32 1.27e-9 Obesity; LIHC cis rs7539409 0.915 rs1977119 chr1:84275509 A/G cg10977910 chr1:84465055 TTLL7 0.75 6.19 0.32 1.68e-9 Alzheimer's disease; LIHC cis rs2522056 1.000 rs2522047 chr5:131795882 G/T cg24060327 chr5:131705240 SLC22A5 0.53 7.16 0.36 4.87e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs1559088 0.625 rs10411739 chr19:33616327 T/C cg17764715 chr19:33622953 WDR88 0.57 7.95 0.4 2.7e-14 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2153535 0.580 rs6597318 chr6:8437289 G/A cg23788917 chr6:8435910 SLC35B3 0.62 9.21 0.45 3.34e-18 Motion sickness; LIHC cis rs8180040 0.966 rs11710322 chr3:47331136 C/T cg27129171 chr3:47204927 SETD2 -0.64 -10.61 -0.5 6.35e-23 Colorectal cancer; LIHC cis rs35306767 0.903 rs12249634 chr10:872744 G/A cg26597838 chr10:835615 NA 1.11 12.56 0.56 4.97e-30 Eosinophil percentage of granulocytes; LIHC cis rs760805 1.000 rs61774728 chr1:25258867 G/C cg22509179 chr1:25234806 RUNX3 -0.37 -7.84 -0.39 5.88e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs10504073 0.647 rs12156111 chr8:50017328 G/C cg00325661 chr8:49890786 NA 0.31 7.07 0.36 8.65e-12 Blood metabolite ratios; LIHC cis rs7534824 0.625 rs61780284 chr1:101355166 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 7.02 0.36 1.17e-11 Refractive astigmatism; LIHC cis rs4975616 0.839 rs2447853 chr5:1333077 A/G cg06550200 chr5:1325588 CLPTM1L -0.64 -10.04 -0.48 5.81e-21 Lung cancer; LIHC cis rs7520050 0.931 rs6698247 chr1:46371486 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.73 0.3 2.16e-8 Red blood cell count;Reticulocyte count; LIHC cis rs9309473 1.000 rs6755217 chr2:73641285 C/T cg20560298 chr2:73613845 ALMS1 -0.57 -6.39 -0.33 5.51e-10 Metabolite levels; LIHC cis rs7208859 0.623 rs7220999 chr17:29149298 C/T cg14067834 chr17:29058358 SUZ12P 0.68 6.62 0.34 1.38e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs829883 0.664 rs1096148 chr12:98851005 A/G cg25150519 chr12:98850993 NA 0.7 11.21 0.52 4.86e-25 Colorectal adenoma (advanced); LIHC cis rs10504073 0.584 rs4873300 chr8:49902201 C/G cg00325661 chr8:49890786 NA 0.39 9.53 0.46 2.97e-19 Blood metabolite ratios; LIHC cis rs2230307 0.536 rs482466 chr1:100488177 C/T cg24955406 chr1:100503596 HIAT1 0.61 6.07 0.31 3.35e-9 Carotid intima media thickness; LIHC cis rs11628318 0.588 rs12892602 chr14:103114091 T/C cg23461800 chr14:103021989 NA 0.39 5.94 0.31 7.14e-9 Platelet count; LIHC cis rs365132 1.000 rs2292255 chr5:176334195 C/T cg16309518 chr5:176445507 NA -0.58 -11.51 -0.53 3.91e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs655641 0.911 rs618629 chr11:85689435 T/C cg09030501 chr11:85779252 PICALM -0.51 -6.15 -0.32 2.17e-9 Platelet count; LIHC cis rs7633857 0.512 rs7611005 chr3:160698549 A/T cg03342759 chr3:160939853 NMD3 -0.41 -5.83 -0.3 1.3e-8 Educational attainment (years of education); LIHC cis rs7539409 0.764 rs4001465 chr1:84285304 T/C cg10977910 chr1:84465055 TTLL7 0.73 6.93 0.35 2.04e-11 Alzheimer's disease; LIHC cis rs11719291 0.504 rs71324924 chr3:48865444 G/A cg07636037 chr3:49044803 WDR6 -0.79 -7.76 -0.39 9.98e-14 Cognitive function; LIHC cis rs796364 0.906 rs281784 chr2:200749749 T/A cg12253985 chr2:200820533 C2orf60;C2orf47 0.78 9.09 0.44 8.32e-18 Schizophrenia; LIHC cis rs9790314 1.000 rs163328 chr3:161073599 A/G cg04691961 chr3:161091175 C3orf57 -0.46 -7.23 -0.36 3.28e-12 Morning vs. evening chronotype; LIHC cis rs79976124 0.879 rs10944856 chr6:66636960 G/C cg07460842 chr6:66804631 NA 0.65 6.79 0.34 4.98e-11 Type 2 diabetes; LIHC cis rs4803468 0.934 rs2317131 chr19:41885151 C/T cg09537434 chr19:41945824 ATP5SL -0.99 -20.22 -0.74 2.3e-60 Height; LIHC cis rs9733 0.519 rs11807450 chr1:150677719 C/T cg15448220 chr1:150897856 SETDB1 0.43 6.76 0.34 5.86e-11 Tonsillectomy; LIHC cis rs1499614 1.000 rs2659903 chr7:66180931 G/A cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC trans rs75804782 0.521 rs56121087 chr2:239435766 A/G cg01134436 chr17:81009848 B3GNTL1 0.74 6.39 0.33 5.39e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs10540 1.000 rs61876340 chr11:495699 A/C cg03352830 chr11:487213 PTDSS2 0.82 6.88 0.35 2.87e-11 Body mass index; LIHC cis rs11792861 0.781 rs28361152 chr9:111727529 T/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.88 -0.35 2.89e-11 Menarche (age at onset); LIHC cis rs1267303 0.716 rs942255 chr1:46989792 C/T cg25110126 chr1:46999211 NA 0.42 5.71 0.3 2.41e-8 Monobrow; LIHC cis rs7833790 0.676 rs7834555 chr8:82697625 A/G cg02079420 chr8:82753780 SNX16 0.33 5.98 0.31 5.71e-9 Diastolic blood pressure; LIHC cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg02290350 chr8:58132656 NA 0.39 8.47 0.42 7.16e-16 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg11494091 chr17:61959527 GH2 0.4 7.36 0.37 1.39e-12 Prudent dietary pattern; LIHC cis rs11608355 0.545 rs11612500 chr12:109897136 T/C cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs769267 0.895 rs2916073 chr19:19528324 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.53 7.98 0.4 2.31e-14 Tonsillectomy; LIHC cis rs727505 0.821 rs67167896 chr7:124614127 T/C cg23710748 chr7:124431027 NA -0.34 -6.04 -0.31 4.07e-9 Lewy body disease; LIHC cis rs4919087 0.715 rs793520 chr10:99032375 G/A cg25902810 chr10:99078978 FRAT1 -0.6 -6.88 -0.35 2.9e-11 Monocyte count; LIHC cis rs8141529 0.504 rs6005915 chr22:29233262 A/G cg15103426 chr22:29168792 CCDC117 0.62 9.83 0.47 3.11e-20 Lymphocyte counts; LIHC cis rs9768139 0.733 rs13225172 chr7:158120334 G/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.93 -0.31 7.47e-9 Calcium levels; LIHC cis rs12824058 0.831 rs4759451 chr12:130812739 G/A cg26677194 chr12:130822605 PIWIL1 0.51 7.25 0.36 2.88e-12 Menopause (age at onset); LIHC cis rs12594515 0.967 rs8039088 chr15:45990178 T/C cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs4819052 0.851 rs2330011 chr21:46658498 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.54 0.5 1.14e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs875971 0.767 rs1695815 chr7:65831344 A/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs1799949 0.965 rs9897425 chr17:41430179 C/G cg25072359 chr17:41440525 NA 0.38 6.08 0.31 3.14e-9 Menopause (age at onset); LIHC cis rs769267 0.895 rs2905435 chr19:19495954 G/A cg03709012 chr19:19516395 GATAD2A -1.01 -18.04 -0.7 1.33e-51 Tonsillectomy; LIHC cis rs9303401 0.614 rs28687626 chr17:57191904 G/A cg25039879 chr17:56429692 SUPT4H1 0.8 8.82 0.43 5.77e-17 Cognitive test performance; LIHC cis rs7193541 0.965 rs7199068 chr16:74698263 C/G cg01733217 chr16:74700730 RFWD3 0.53 10.25 0.48 1.12e-21 Multiple myeloma; LIHC trans rs561341 1.000 rs530209 chr17:30315287 A/G cg20587970 chr11:113659929 NA -1.38 -11.71 -0.53 7.6e-27 Hip circumference adjusted for BMI; LIHC cis rs17253792 0.822 rs75663029 chr14:56092385 T/C cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs1707322 1.000 rs6671754 chr1:46433990 A/G cg03146154 chr1:46216737 IPP 0.48 7.8 0.39 7.33e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6831352 0.589 rs2602836 chr4:100014805 C/T cg13256891 chr4:100009986 ADH5 -0.52 -7.36 -0.37 1.39e-12 Alcohol dependence; LIHC cis rs10768122 0.642 rs11033087 chr11:35374044 G/T cg13971030 chr11:35366721 SLC1A2 -0.35 -5.86 -0.3 1.09e-8 Vitiligo; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24167897 chr15:63796719 USP3 0.49 6.83 0.35 3.98e-11 Lung function (FEV1/FVC); LIHC cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg17554472 chr22:41940697 POLR3H 0.55 5.91 0.3 8.18e-9 Vitiligo; LIHC cis rs1982963 0.627 rs2073626 chr14:52488385 A/G cg10843707 chr14:52510701 NID2 0.36 5.91 0.3 8.31e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs875971 0.522 rs709604 chr7:65497434 A/G cg11764359 chr7:65958608 NA -0.69 -9.44 -0.45 5.96e-19 Aortic root size; LIHC trans rs7714584 0.793 rs11955174 chr5:150254391 T/G cg20675040 chr8:143813288 C8orf55 0.34 6.05 0.31 3.8e-9 Crohn's disease; LIHC cis rs7224685 0.569 rs28481302 chr17:4011527 T/G cg09597638 chr17:3907349 NA 0.54 6.47 0.33 3.46e-10 Type 2 diabetes; LIHC cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg03351412 chr1:154909251 PMVK -0.7 -10.47 -0.49 1.89e-22 Prostate cancer; LIHC cis rs2153535 0.580 rs1414348 chr6:8471940 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.17 0.55 1.47e-28 Motion sickness; LIHC cis rs1790761 0.692 rs1269981 chr11:67334959 G/A cg21734168 chr11:67353974 GSTP1 -0.28 -6.76 -0.34 5.88e-11 Mean corpuscular volume; LIHC cis rs57502260 0.704 rs41478448 chr11:68181621 A/G cg20283391 chr11:68216788 NA -0.48 -5.86 -0.3 1.06e-8 Total body bone mineral density (age 45-60); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01353569 chr7:106810328 HBP1 0.46 6.64 0.34 1.26e-10 Pancreatic cancer; LIHC cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg12373951 chr3:133503437 NA 0.46 7.66 0.38 1.94e-13 Iron status biomarkers; LIHC cis rs3820068 0.532 rs72647105 chr1:15935238 C/G cg17385448 chr1:15911702 AGMAT 0.33 5.77 0.3 1.77e-8 Systolic blood pressure; LIHC cis rs35146811 0.771 rs6465762 chr7:99620554 G/A cg22906224 chr7:99728672 NA 0.45 6.39 0.33 5.44e-10 Coronary artery disease; LIHC cis rs7617773 0.563 rs62263035 chr3:48391569 C/T cg11946769 chr3:48343235 NME6 0.54 6.69 0.34 9.37e-11 Coronary artery disease; LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg06420487 chr17:61919686 SMARCD2 0.45 6.13 0.31 2.45e-9 Height; LIHC cis rs748404 0.697 rs546170 chr15:43564849 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.43 7.31 0.37 1.94e-12 Lung cancer; LIHC cis rs4407350 0.788 rs5764879 chr22:44920771 T/C cg26276947 chr22:44892394 LDOC1L 0.33 6.18 0.32 1.86e-9 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.958 rs6454488 chr6:86450842 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.45 -8.59 -0.42 3.06e-16 Response to antipsychotic treatment; LIHC cis rs10870270 1.000 rs10159746 chr10:133742677 C/T cg26149184 chr10:133730230 NA 0.47 7.45 0.37 7.72e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs11864453 0.826 rs6499559 chr16:72132064 G/C cg16558253 chr16:72132732 DHX38 -0.52 -8.17 -0.4 6.17e-15 Fibrinogen levels; LIHC cis rs589448 0.934 rs554591 chr12:69753847 T/C cg14784868 chr12:69753453 YEATS4 0.99 23.08 0.78 1.05e-71 Cerebrospinal fluid biomarker levels; LIHC cis rs2444217 0.868 rs2601792 chr16:4043980 G/A cg09300795 chr16:4042428 ADCY9 0.55 9.74 0.47 6.08e-20 Body mass index; LIHC cis rs6429082 1.000 rs2055127 chr1:235598973 C/T cg26050004 chr1:235667680 B3GALNT2 -0.4 -6.3 -0.32 9.08e-10 Adiposity; LIHC cis rs2439831 1.000 rs2467736 chr15:43784917 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.68 0.59 2.85e-34 Lung cancer in ever smokers; LIHC trans rs8117834 0.574 rs76883031 chr20:8087339 C/T cg00593689 chr4:53575888 NA 0.41 6.84 0.35 3.77e-11 Chronic kidney disease; LIHC cis rs151997 0.649 rs152688 chr5:50211776 C/T cg06027927 chr5:50259733 NA 0.43 6.4 0.33 5.23e-10 Callous-unemotional behaviour; LIHC cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.76 0.39 1e-13 Prudent dietary pattern; LIHC cis rs77633900 0.685 rs2469556 chr15:76650148 G/A cg21673338 chr15:77095150 SCAPER -0.53 -6.15 -0.32 2.15e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs7131987 0.903 rs7970390 chr12:29398655 A/G cg21486233 chr12:29375141 FAR2 0.32 6.35 0.32 6.74e-10 QT interval; LIHC cis rs7674212 0.541 rs2623070 chr4:104037388 A/G cg16532752 chr4:104119610 CENPE 0.45 7.08 0.36 8.4e-12 Type 2 diabetes; LIHC cis rs2710642 0.888 rs13418889 chr2:63079775 T/C cg17519650 chr2:63277830 OTX1 0.44 6.92 0.35 2.28e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs611744 0.934 rs1452021 chr8:109207886 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs7762018 0.514 rs60671539 chr6:170165981 A/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.61 8.93 0.43 2.76e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.68 0.34 9.67e-11 Bipolar disorder; LIHC cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg02951883 chr7:2050386 MAD1L1 -0.54 -7.93 -0.39 3.18e-14 Bipolar disorder and schizophrenia; LIHC cis rs829883 0.646 rs249838 chr12:98874749 C/G cg23471612 chr12:98897216 NA 0.3 5.74 0.3 2.06e-8 Colorectal adenoma (advanced); LIHC cis rs16958440 0.867 rs75228657 chr18:44741063 A/G cg17192377 chr18:44677553 HDHD2 0.92 8.61 0.42 2.67e-16 Sitting height ratio; LIHC cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg22800045 chr5:56110881 MAP3K1 0.68 8.6 0.42 2.87e-16 Initial pursuit acceleration; LIHC cis rs1863824 0.625 rs11202023 chr10:88165453 C/T cg07322936 chr10:88137208 NA -0.46 -6.06 -0.31 3.62e-9 Schizophrenia; LIHC trans rs9354352 0.818 rs9453548 chr6:66691885 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.59 -9.29 -0.45 1.78e-18 Initial pursuit acceleration in psychotic disorders; LIHC cis rs7317038 0.745 rs75590443 chr13:114015421 A/T cg24344662 chr13:114018021 GRTP1 -0.44 -6.39 -0.33 5.48e-10 Mean platelet volume; LIHC cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg11060661 chr22:24314208 DDT;DDTL -0.62 -10.68 -0.5 3.68e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs208520 0.690 rs12204512 chr6:66710486 C/T cg07460842 chr6:66804631 NA 0.74 8.7 0.43 1.46e-16 Exhaled nitric oxide output; LIHC cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs2795502 1.000 rs2744090 chr10:43339614 G/C cg27426351 chr10:43362370 NA -0.46 -5.82 -0.3 1.38e-8 Blood protein levels; LIHC cis rs1059312 0.966 rs7135968 chr12:129280066 G/A cg09035930 chr12:129282057 SLC15A4 0.69 13.29 0.58 8.71e-33 Systemic lupus erythematosus; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg10150615 chr22:24372951 LOC391322 -0.49 -6.87 -0.35 3.12e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg23794135 chr12:81190974 NA 0.34 6.31 0.32 8.51e-10 Hepatitis; LIHC cis rs7918232 0.941 rs1775350 chr10:27441973 C/T cg14442939 chr10:27389572 ANKRD26 -0.71 -6.72 -0.34 7.44e-11 Breast cancer; LIHC cis rs4906332 1.000 rs10459573 chr14:103925457 A/C cg19000871 chr14:103996768 TRMT61A -0.47 -7.94 -0.39 2.98e-14 Coronary artery disease; LIHC cis rs9902453 0.817 rs4794861 chr17:28183174 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 10.23 0.48 1.32e-21 Coffee consumption (cups per day); LIHC cis rs2153535 0.580 rs6421949 chr6:8531769 G/A cg21535247 chr6:8435926 SLC35B3 0.65 8.49 0.42 6.54e-16 Motion sickness; LIHC cis rs7903847 0.642 rs11817852 chr10:99158426 C/T cg20016023 chr10:99160130 RRP12 -0.43 -6.58 -0.34 1.73e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs12477438 0.765 rs7591992 chr2:99668954 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs4970988 0.556 rs6681426 chr1:150586971 G/A cg13175981 chr1:150552382 MCL1 0.48 6.51 0.33 2.61e-10 Urate levels; LIHC cis rs4648739 0.613 rs13303201 chr1:1903712 G/T cg03688085 chr1:1910585 KIAA1751 -0.49 -9.59 -0.46 1.84e-19 Severe influenza A (H1N1) infection; LIHC cis rs2404602 0.647 rs11631959 chr15:77040048 T/C cg03037974 chr15:76606532 NA -0.6 -10.24 -0.48 1.18e-21 Blood metabolite levels; LIHC cis rs7617773 1.000 rs7617773 chr3:48193515 C/T cg11946769 chr3:48343235 NME6 -0.61 -7.96 -0.4 2.56e-14 Coronary artery disease; LIHC cis rs11190604 1.000 rs2295772 chr10:102265183 G/A cg07080220 chr10:102295463 HIF1AN 0.57 8.15 0.4 6.94e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs6960043 0.714 rs7784091 chr7:15047637 A/G cg19272540 chr7:15055459 NA -0.24 -6.71 -0.34 8.12e-11 Type 2 diabetes; LIHC cis rs9341808 0.528 rs2322753 chr6:81042865 C/G cg08355045 chr6:80787529 NA 0.33 6.77 0.34 5.6e-11 Sitting height ratio; LIHC cis rs10540 0.908 rs12792111 chr11:520921 G/C cg03576123 chr11:487126 PTDSS2 -1.03 -7.24 -0.36 3.01e-12 Body mass index; LIHC trans rs2073499 0.679 rs2624842 chr3:50196418 A/C cg21659725 chr3:3221576 CRBN 0.53 6.04 0.31 4.03e-9 Schizophrenia; LIHC cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg15691649 chr6:25882328 NA -1.05 -16.49 -0.67 2.34e-45 Urate levels; LIHC cis rs2108225 0.900 rs2395930 chr7:107451677 T/C cg18560240 chr7:107437656 SLC26A3 -0.41 -6.52 -0.33 2.56e-10 Ulcerative colitis; LIHC cis rs875971 0.861 rs801215 chr7:66011938 A/T cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.4e-9 Aortic root size; LIHC cis rs798554 0.660 rs2644275 chr7:2854010 G/A cg19717773 chr7:2847554 GNA12 -0.43 -7.63 -0.38 2.36e-13 Height; LIHC cis rs1707322 0.686 rs1541131 chr1:46084934 G/A cg03146154 chr1:46216737 IPP -0.58 -9.87 -0.47 2.24e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3806843 1.000 rs10057161 chr5:140156831 C/T cg26395211 chr5:140044315 WDR55 -0.43 -6.37 -0.33 5.99e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs60871478 0.947 rs7790823 chr7:788923 T/G cg27478167 chr7:817139 HEATR2 -0.42 -5.9 -0.3 8.71e-9 Cerebrospinal P-tau181p levels; LIHC cis rs9300255 0.550 rs10772997 chr12:123719880 C/A cg05973401 chr12:123451056 ABCB9 0.43 5.94 0.31 7.13e-9 Neutrophil percentage of white cells; LIHC cis rs1707322 0.758 rs10789474 chr1:46250040 G/T cg06784218 chr1:46089804 CCDC17 0.38 6.84 0.35 3.67e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs727505 1.000 rs6971909 chr7:124525517 C/T cg23710748 chr7:124431027 NA -0.32 -5.91 -0.3 8.38e-9 Lewy body disease; LIHC cis rs6429082 0.818 rs291391 chr1:235649955 A/G cg26050004 chr1:235667680 B3GALNT2 0.51 8.06 0.4 1.31e-14 Adiposity; LIHC cis rs61041384 0.661 rs4148857 chr12:123539955 T/C cg00376283 chr12:123451042 ABCB9 -0.6 -5.72 -0.3 2.37e-8 Schizophrenia; LIHC cis rs7937840 0.597 rs3867138 chr11:61911422 C/T cg01969543 chr11:61895209 INCENP -0.49 -6.18 -0.32 1.86e-9 Breast cancer; LIHC cis rs2842992 0.789 rs3818300 chr6:160201677 G/A cg16489826 chr6:160211363 TCP1;MRPL18 0.48 8.49 0.42 6.2e-16 Age-related macular degeneration (geographic atrophy); LIHC cis rs903552 0.800 rs6598479 chr15:102005913 A/C cg25677261 chr15:102009856 PCSK6 -0.5 -6.69 -0.34 9.06e-11 Diabetic kidney disease; LIHC trans rs2727020 0.681 rs1976901 chr11:49378697 T/C cg03929089 chr4:120376271 NA -0.84 -15.05 -0.63 1.2e-39 Coronary artery disease; LIHC cis rs1707322 0.686 rs2275085 chr1:46085852 C/T cg24296786 chr1:45957014 TESK2 0.4 5.85 0.3 1.16e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7216064 0.911 rs6504551 chr17:65903326 T/G cg12091567 chr17:66097778 LOC651250 -0.64 -9.61 -0.46 1.62e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs2012796 0.785 rs61986593 chr14:81840659 G/A cg02996355 chr14:81879375 NA 0.77 12.37 0.56 2.62e-29 Night sleep phenotypes; LIHC cis rs1707322 0.752 rs8179402 chr1:46142466 C/A cg06784218 chr1:46089804 CCDC17 0.41 7.77 0.39 9.04e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4759375 0.790 rs9739171 chr12:123840994 T/G cg00376283 chr12:123451042 ABCB9 0.49 6.31 0.32 8.57e-10 HDL cholesterol; LIHC cis rs4638749 0.677 rs7594896 chr2:108835502 C/T cg06795125 chr2:108905320 SULT1C2 -0.29 -5.74 -0.3 2.14e-8 Blood pressure; LIHC cis rs10883723 0.810 rs1409311 chr10:104282160 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.64 0.56 2.67e-30 Allergic disease (asthma, hay fever or eczema); LIHC cis rs10504229 0.593 rs12216730 chr8:58003894 C/T cg20607798 chr8:58055168 NA 0.48 6.51 0.33 2.75e-10 Developmental language disorder (linguistic errors); LIHC cis rs6988985 0.560 rs7826809 chr8:143925609 C/T cg23373978 chr8:143916136 GML -0.29 -6.17 -0.32 1.88e-9 Plasma androstenedione levels in resected early stage-receptor positive breast cancer; LIHC cis rs12701220 0.655 rs34344742 chr7:1149288 C/G cg16145915 chr7:1198662 ZFAND2A -0.34 -6.71 -0.34 8.34e-11 Bronchopulmonary dysplasia; LIHC cis rs7615952 0.576 rs2276726 chr3:125826287 C/G cg05084668 chr3:125655381 ALG1L -0.38 -6.04 -0.31 3.99e-9 Blood pressure (smoking interaction); LIHC cis rs34172651 0.917 rs11642302 chr16:24770856 G/A cg00339695 chr16:24857497 SLC5A11 0.32 5.76 0.3 1.85e-8 Intelligence (multi-trait analysis); LIHC cis rs7945718 0.621 rs10831896 chr11:12693361 G/A cg25843174 chr11:12811716 TEAD1 0.34 7.85 0.39 5.51e-14 Educational attainment (years of education); LIHC cis rs9457247 0.765 rs12212247 chr6:167413539 T/C cg12798992 chr6:167411361 FGFR1OP 0.48 7.27 0.37 2.53e-12 Crohn's disease; LIHC cis rs1494950 1.000 rs55733122 chr4:15048782 C/G cg12377275 chr4:15005593 CPEB2 -0.85 -7.78 -0.39 8.87e-14 Political ideology; LIHC cis rs7937890 1.000 rs6486190 chr11:14401216 A/C cg22961513 chr11:14280813 SPON1 -0.44 -6.89 -0.35 2.76e-11 Mitochondrial DNA levels; LIHC cis rs4474465 1.000 rs10899533 chr11:78208480 T/C cg27205649 chr11:78285834 NARS2 0.37 5.79 0.3 1.58e-8 Alzheimer's disease (survival time); LIHC cis rs60871478 1.000 rs62432253 chr7:802928 A/G cg13301601 chr7:774633 HEATR2 -0.41 -5.81 -0.3 1.43e-8 Cerebrospinal P-tau181p levels; LIHC trans rs35110281 0.627 rs7283362 chr21:44973667 C/G cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.49 6.83 0.35 3.99e-11 Mean corpuscular volume; LIHC cis rs4407350 0.967 rs5764884 chr22:44922843 G/T cg26276947 chr22:44892394 LDOC1L 0.33 5.88 0.3 1e-8 Intelligence (multi-trait analysis); LIHC cis rs4523957 0.583 rs2760743 chr17:2017079 A/C cg16513277 chr17:2031491 SMG6 0.6 9.92 0.47 1.51e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7264396 0.635 rs6058358 chr20:34492560 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.5 -0.49 1.57e-22 Total cholesterol levels; LIHC cis rs8141529 1.000 rs8141529 chr22:29269692 A/G cg02153584 chr22:29168773 CCDC117 0.39 5.97 0.31 5.82e-9 Lymphocyte counts; LIHC cis rs735396 0.770 rs1169301 chr12:121431300 C/T cg25281562 chr12:121454272 C12orf43 0.37 6.29 0.32 9.83e-10 N-glycan levels; LIHC cis rs317689 0.658 rs479971 chr12:69672471 A/G cg22834771 chr12:69754056 YEATS4 -0.4 -6.0 -0.31 4.91e-9 Response to diuretic therapy; LIHC cis rs6912958 0.781 rs4464759 chr6:88282621 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.72 -0.39 1.28e-13 Monocyte percentage of white cells; LIHC cis rs4006360 0.646 rs9902561 chr17:39295384 G/A cg20663846 chr17:39254439 KRTAP4-8 0.2 5.77 0.3 1.76e-8 Bipolar disorder and schizophrenia; LIHC cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg15691649 chr6:25882328 NA 0.51 7.0 0.35 1.35e-11 Blood metabolite levels; LIHC cis rs1005277 0.602 rs1831315 chr10:38473353 T/C cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.2 -0.32 1.6e-9 Extrinsic epigenetic age acceleration; LIHC cis rs73001065 0.636 rs56241616 chr19:19506092 C/T cg03709012 chr19:19516395 GATAD2A 0.94 10.56 0.5 9.78e-23 LDL cholesterol; LIHC trans rs877282 0.898 rs11253349 chr10:765897 C/G cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC trans rs804280 0.662 rs11250164 chr8:11610686 C/T cg24805985 chr8:25045589 DOCK5 0.31 6.43 0.33 4.32e-10 Myopia (pathological); LIHC cis rs1003719 0.715 rs2835649 chr21:38552230 C/T cg10648535 chr21:38446584 PIGP;TTC3 0.7 10.62 0.5 5.63e-23 Eye color traits; LIHC cis rs75908454 1.000 rs75255669 chr6:169962828 C/T cg19338460 chr6:170058176 WDR27 -0.83 -7.48 -0.38 6.2800000000000005e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs2439831 0.850 rs12441984 chr15:44126285 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.62 8.69 0.43 1.58e-16 Lung cancer in ever smokers; LIHC cis rs757081 0.667 rs12577525 chr11:17260116 G/A cg15432903 chr11:17409602 KCNJ11 -0.42 -5.81 -0.3 1.41e-8 Systolic blood pressure; LIHC cis rs35306767 0.761 rs11253558 chr10:1043983 T/C cg20503657 chr10:835505 NA 0.82 7.77 0.39 9.5e-14 Eosinophil percentage of granulocytes; LIHC cis rs344364 0.511 rs2917519 chr16:1950479 C/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.29 -0.37 2.1e-12 Glomerular filtration rate in chronic kidney disease; LIHC trans rs78049276 0.736 rs10305838 chr4:148400256 T/C cg13149281 chr14:23389818 RBM23;PRMT5 -0.58 -7.76 -0.39 9.85e-14 Pulse pressure; LIHC cis rs7116495 0.619 rs7116188 chr11:71841753 A/G cg26138937 chr11:71823887 C11orf51 0.82 8.1 0.4 9.95e-15 Severe influenza A (H1N1) infection; LIHC cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg19318889 chr4:1322082 MAEA 0.47 6.48 0.33 3.11e-10 Obesity-related traits; LIHC cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg05368731 chr17:41323189 NBR1 0.71 12.09 0.55 2.96e-28 Menopause (age at onset); LIHC cis rs61776719 0.875 rs10890238 chr1:38445654 A/T cg17077180 chr1:38461687 NA 0.4 6.49 0.33 2.97e-10 Coronary artery disease; LIHC cis rs7223966 1.000 rs8080211 chr17:61729882 A/G cg05941027 chr17:61774174 LIMD2 0.36 7.27 0.37 2.4e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs8017423 0.935 rs12884698 chr14:90750566 G/A cg14092571 chr14:90743983 NA 0.44 6.95 0.35 1.87e-11 Mortality in heart failure; LIHC cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs7395581 0.918 rs1375688 chr11:47327217 G/A cg25783544 chr11:47291846 MADD 0.41 5.94 0.31 6.98e-9 HDL cholesterol; LIHC cis rs11690935 0.851 rs10174055 chr2:172858214 C/T cg13550731 chr2:172543902 DYNC1I2 -0.83 -14.56 -0.62 1.07e-37 Schizophrenia; LIHC cis rs2239547 0.522 rs2336162 chr3:52951519 C/T cg18404041 chr3:52824283 ITIH1 0.43 5.98 0.31 5.48e-9 Schizophrenia; LIHC cis rs10911232 0.507 rs28477876 chr1:183019882 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.49 0.49 1.7e-22 Hypertriglyceridemia; LIHC cis rs1691799 0.899 rs1168304 chr12:66738667 A/C cg16791601 chr12:66731901 HELB -0.57 -13.84 -0.6 6.43e-35 White blood cell count (basophil); LIHC cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg21016266 chr12:122356598 WDR66 0.56 7.73 0.39 1.24e-13 Mean corpuscular volume; LIHC cis rs1570884 0.516 rs7330830 chr13:50167929 T/A cg03651054 chr13:50194643 NA 0.4 7.01 0.35 1.26e-11 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs7223966 1.000 rs13380863 chr17:61780793 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 6.53 0.33 2.38e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs28829049 0.731 rs7537573 chr1:19373605 C/T cg13387374 chr1:19411106 UBR4 0.45 6.61 0.34 1.5e-10 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs875971 0.862 rs11769079 chr7:65842128 G/A cg11764359 chr7:65958608 NA 0.85 15.19 0.63 3.43e-40 Aortic root size; LIHC cis rs2404602 0.735 rs12903874 chr15:76693318 A/T cg23625390 chr15:77176239 SCAPER -0.48 -8.04 -0.4 1.5e-14 Blood metabolite levels; LIHC trans rs916888 0.821 rs199513 chr17:44856932 A/G cg13957321 chr17:43675089 NA -0.48 -8.01 -0.4 1.88e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10489202 1.000 rs2420 chr1:167886502 A/T cg24449463 chr1:168025552 DCAF6 -0.52 -6.27 -0.32 1.07e-9 Schizophrenia; LIHC cis rs8077889 0.763 rs4792913 chr17:41854497 T/C cg26893861 chr17:41843967 DUSP3 1.05 18.25 0.7 1.97e-52 Triglycerides; LIHC cis rs7712401 0.755 rs4283786 chr5:122101050 T/C cg18764291 chr5:122110994 SNX2 0.35 6.07 0.31 3.37e-9 Mean platelet volume; LIHC cis rs12701220 0.655 rs34696066 chr7:1140919 C/T cg04498913 chr7:1135747 C7orf50 0.45 7.21 0.36 3.52e-12 Bronchopulmonary dysplasia; LIHC cis rs801193 0.613 rs2659900 chr7:66184443 G/C cg18876405 chr7:65276391 NA 0.34 6.28 0.32 1.06e-9 Aortic root size; LIHC cis rs875971 1.000 rs4718343 chr7:65874288 T/G cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC cis rs8020095 0.528 rs2319777 chr14:67810033 C/T cg03487553 chr14:67822707 ATP6V1D -0.35 -6.13 -0.31 2.48e-9 Depression (quantitative trait); LIHC cis rs1552244 0.554 rs17050704 chr3:10045734 T/C cg21531657 chr3:10005747 TMEM111 0.38 5.71 0.3 2.42e-8 Alzheimer's disease; LIHC cis rs2274273 0.840 rs72715769 chr14:55762429 C/G cg01864836 chr14:55583639 NA -0.37 -6.63 -0.34 1.35e-10 Protein biomarker; LIHC cis rs332507 0.830 rs1846892 chr3:124399293 A/G cg05980111 chr3:124395277 KALRN 0.46 7.07 0.36 8.83e-12 Plateletcrit; LIHC cis rs9640161 0.673 rs34489187 chr7:150044379 G/A cg10018233 chr7:150070692 REPIN1 0.55 8.52 0.42 5.04e-16 Blood protein levels;Circulating chemerin levels; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg00875911 chr4:1224246 CTBP1 0.4 6.26 0.32 1.14e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs12908161 0.959 rs17598603 chr15:85200211 C/G cg17507749 chr15:85114479 UBE2QP1 -0.56 -6.24 -0.32 1.28e-9 Schizophrenia; LIHC cis rs4517514 0.509 rs12224461 chr11:89871111 C/T cg05041596 chr11:89867385 NAALAD2 0.41 6.43 0.33 4.34e-10 Trans fatty acid levels; LIHC cis rs4654899 0.785 rs10916911 chr1:21290061 C/T cg08539965 chr1:21396338 EIF4G3 0.34 6.15 0.32 2.22e-9 Superior frontal gyrus grey matter volume; LIHC cis rs6456156 0.586 rs12525855 chr6:167480013 T/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.65 -0.42 2.04e-16 Primary biliary cholangitis; LIHC cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs3749237 0.595 rs1464566 chr3:49459376 T/C cg03060546 chr3:49711283 APEH 0.6 10.07 0.48 4.76e-21 Resting heart rate; LIHC cis rs2153535 0.580 rs4365970 chr6:8453813 C/T cg23788917 chr6:8435910 SLC35B3 -0.58 -8.27 -0.41 3.07e-15 Motion sickness; LIHC cis rs734999 0.545 rs10910106 chr1:2538886 G/T cg18854424 chr1:2615690 NA 0.33 7.08 0.36 8e-12 Ulcerative colitis; LIHC trans rs9929218 0.817 rs3114400 chr16:68719430 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.74 -10.88 -0.51 7.1e-24 Colorectal cancer; LIHC cis rs60871478 1.000 rs4720930 chr7:808073 G/A cg27478167 chr7:817139 HEATR2 -0.42 -5.94 -0.31 6.93e-9 Cerebrospinal P-tau181p levels; LIHC cis rs651907 0.557 rs7651406 chr3:101393296 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.7 11.74 0.54 5.46e-27 Colorectal cancer; LIHC cis rs933688 1.000 rs1964292 chr5:90743608 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 16.2 0.66 3.29e-44 Smoking behavior; LIHC cis rs114532231 0.661 rs75764836 chr2:86526863 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.68 -6.91 -0.35 2.45e-11 Asymmetrical dimethylarginine levels; LIHC cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg10755058 chr3:40428713 ENTPD3 0.38 6.49 0.33 2.94e-10 Renal cell carcinoma; LIHC cis rs4845459 0.967 rs4845452 chr1:152591647 A/G cg20634798 chr1:152595351 LCE3A -0.31 -5.98 -0.31 5.56e-9 Psoriasis; LIHC cis rs780094 0.544 rs780110 chr2:27685388 G/A cg22903471 chr2:27725779 GCKR -0.47 -7.9 -0.39 3.88e-14 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg06873352 chr17:61820015 STRADA 0.58 8.75 0.43 1.02e-16 Height; LIHC cis rs2380220 0.606 rs4559095 chr6:95994154 A/C cg23517279 chr6:96025343 MANEA 0.57 6.48 0.33 3.21e-10 Behavioural disinhibition (generation interaction); LIHC cis rs34779708 0.966 rs11010129 chr10:35510822 T/C cg04310649 chr10:35416472 CREM -0.43 -5.79 -0.3 1.57e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs8180040 0.966 rs13072802 chr3:47346415 G/C cg02527881 chr3:46936655 PTH1R -0.31 -6.03 -0.31 4.15e-9 Colorectal cancer; LIHC cis rs7772486 0.875 rs12194437 chr6:146411440 A/G cg13319975 chr6:146136371 FBXO30 -0.38 -6.11 -0.31 2.78e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs66782572 1 rs66782572 chr3:52567617 A/G cg17372223 chr3:52568218 NT5DC2 0.36 5.99 0.31 5.36e-9 Hemoglobin concentration; LIHC cis rs4800452 0.956 rs4239436 chr18:20731930 A/G cg26136497 chr18:20735537 CABLES1 -0.45 -5.97 -0.31 5.94e-9 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC cis rs929354 0.772 rs3802123 chr7:156970641 G/A cg16102536 chr7:156981717 UBE3C 0.36 5.82 0.3 1.35e-8 Body mass index; LIHC cis rs9814567 1.000 rs11927068 chr3:134266321 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs71658797 0.536 rs12039708 chr1:77947009 C/T cg04606550 chr5:14226569 TRIO 0.38 6.13 0.31 2.45e-9 Lung cancer in ever smokers;Lung cancer;Lung adenocarcinoma; LIHC cis rs7208859 0.673 rs11658344 chr17:29207745 G/T cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6463523 0.933 rs4724821 chr7:762544 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.97 16.86 0.67 7.67e-47 Subjective well-being; LIHC trans rs3960554 0.808 rs3779419 chr7:75695081 G/A cg19862616 chr7:65841803 NCRNA00174 0.62 8.8 0.43 6.96e-17 Eotaxin levels; LIHC cis rs892961 0.899 rs35217221 chr17:75412385 G/A cg05865280 chr17:75406074 SEPT9 0.64 13.1 0.58 4.87e-32 Airflow obstruction; LIHC cis rs10876993 0.928 rs10877001 chr12:58083077 T/C cg18357645 chr12:58087776 OS9 -0.51 -8.37 -0.41 1.49e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs8180040 1.000 rs11714294 chr3:47339723 G/A cg27129171 chr3:47204927 SETD2 -0.67 -11.37 -0.52 1.3e-25 Colorectal cancer; LIHC cis rs473651 0.777 rs550890 chr2:239332555 G/A cg01753270 chr2:239240285 TRAF3IP1 0.32 6.18 0.32 1.82e-9 Multiple system atrophy; LIHC cis rs780096 0.506 rs56076827 chr2:27676287 A/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.6 -0.34 1.55e-10 Total body bone mineral density; LIHC cis rs28595532 1.000 rs11938970 chr4:119660152 A/G cg11846333 chr4:119757529 SEC24D 0.68 6.09 0.31 3.06e-9 Cannabis dependence symptom count; LIHC cis rs765787 0.530 rs10467979 chr15:45521270 G/A cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.7e-10 Uric acid levels; LIHC cis rs7847628 0.587 rs12684934 chr9:123593159 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.76 12.99 0.57 1.19e-31 Birth weight; LIHC cis rs9896052 0.591 rs7212620 chr17:73461930 A/T cg23244877 chr17:73518230 TSEN54 0.34 5.74 0.3 2.04e-8 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC trans rs4704846 0.660 rs246879 chr5:156556846 T/G cg02632742 chr2:60187357 NA -0.6 -6.04 -0.31 3.99e-9 Blood protein levels; LIHC cis rs4700695 1.000 rs3846481 chr5:65417803 T/C cg21114390 chr5:65439923 SFRS12 -0.46 -5.75 -0.3 1.93e-8 Facial morphology (factor 19); LIHC cis rs4919087 0.962 rs10882883 chr10:99013312 A/G cg25902810 chr10:99078978 FRAT1 0.62 8.98 0.44 1.88e-17 Monocyte count; LIHC cis rs611744 0.967 rs475865 chr8:109235858 G/C cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs778371 0.676 rs17164 chr2:233593499 C/T cg08000102 chr2:233561755 GIGYF2 0.72 9.0 0.44 1.56e-17 Schizophrenia; LIHC cis rs4908760 0.931 rs1463049 chr1:8597108 A/T cg20416874 chr1:8611966 RERE -0.7 -15.26 -0.64 1.89e-40 Vitiligo; LIHC cis rs1707322 0.821 rs11211182 chr1:46240170 G/A cg03146154 chr1:46216737 IPP 0.55 8.54 0.42 4.34e-16 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7618915 0.781 rs12489732 chr3:52566820 C/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.46 0.33 3.54e-10 Bipolar disorder; LIHC cis rs7586673 1.000 rs7586673 chr2:161923520 C/A cg16506815 chr2:162101123 NA 0.47 7.77 0.39 9.13e-14 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.851 rs17552292 chr9:111891954 C/T cg05043794 chr9:111880884 C9orf5 -0.29 -6.83 -0.35 3.85e-11 Menarche (age at onset); LIHC cis rs244293 0.965 rs244361 chr17:53191356 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.58 -0.38 3.26e-13 Menarche (age at onset); LIHC cis rs875971 0.545 rs73146609 chr7:65767464 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.24 0.36 3.06e-12 Aortic root size; LIHC cis rs881375 0.967 rs2239658 chr9:123671837 A/G cg14580859 chr9:123691850 NA 0.39 6.79 0.34 5.1e-11 Rheumatoid arthritis; LIHC cis rs11098499 0.954 rs10031483 chr4:120422636 T/C cg09307838 chr4:120376055 NA 0.77 12.31 0.55 4.55e-29 Corneal astigmatism; LIHC cis rs2645694 0.626 rs2645709 chr4:77824474 G/A cg06046430 chr4:77819534 ANKRD56 0.49 6.51 0.33 2.75e-10 Emphysema distribution in smoking; LIHC cis rs17685 0.712 rs869805 chr7:75688596 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.34 -0.32 7.24e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg07308232 chr7:1071921 C7orf50 -0.47 -7.89 -0.39 3.99e-14 Longevity;Endometriosis; LIHC cis rs9303401 1.000 rs6503882 chr17:56915761 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.43 6.46 0.33 3.54e-10 Cognitive test performance; LIHC cis rs16912285 0.688 rs12801480 chr11:24270146 G/A ch.11.24196551F chr11:24239977 NA 0.77 10.48 0.49 1.86e-22 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs17685 0.816 rs11763076 chr7:75765963 C/T cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11190604 0.806 rs11190510 chr10:102157175 G/A cg07080220 chr10:102295463 HIF1AN 0.45 6.08 0.31 3.23e-9 Palmitoleic acid (16:1n-7) levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27305525 chr1:154955752 FLAD1 0.47 7.3 0.37 1.99e-12 Pancreatic cancer; LIHC cis rs11608355 0.576 rs1477117 chr12:109888779 A/G cg05360138 chr12:110035743 NA -0.95 -10.48 -0.49 1.78e-22 Neuroticism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03009463 chr7:17980271 SNX13 -0.48 -6.64 -0.34 1.26e-10 Pancreatic cancer; LIHC cis rs1215050 0.791 rs9993992 chr4:98810851 C/G cg05340658 chr4:99064831 C4orf37 0.38 5.73 0.3 2.2e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs3812111 0.658 rs513218 chr6:116480458 A/G cg08036074 chr6:116424633 NT5DC1 -0.46 -7.73 -0.39 1.17e-13 Age-related macular degeneration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18029761 chr10:134901301 GPR123 -0.44 -7.56 -0.38 3.69e-13 Cognitive function; LIHC cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs208520 0.526 rs1385219 chr6:66754476 C/T cg07460842 chr6:66804631 NA 0.84 14.98 0.63 2.33e-39 Exhaled nitric oxide output; LIHC cis rs79149102 0.579 rs78664321 chr15:75339575 G/A cg15902774 chr15:75289873 SCAMP5 0.46 6.43 0.33 4.32e-10 Lung cancer; LIHC cis rs11792861 0.816 rs113624314 chr9:111689953 G/A cg05043794 chr9:111880884 C9orf5 -0.29 -6.93 -0.35 2.07e-11 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27570636 chr1:214454189 SMYD2 0.48 7.19 0.36 3.99e-12 Pancreatic cancer; LIHC cis rs7188697 0.922 rs40188 chr16:58567761 T/A cg02549819 chr16:58548995 SETD6 -0.45 -7.16 -0.36 5.04e-12 QT interval; LIHC cis rs9303280 0.901 rs12936231 chr17:38029120 C/G cg11212589 chr17:38028394 ZPBP2 0.35 7.39 0.37 1.13e-12 Self-reported allergy; LIHC cis rs3096299 0.685 rs2911244 chr16:89521860 A/G cg02187348 chr16:89574699 SPG7 0.63 9.97 0.47 1.03e-20 Multiple myeloma (IgH translocation); LIHC cis rs8005677 1.000 rs8016061 chr14:23375809 A/G cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 3.07e-9 Cognitive ability (multi-trait analysis); LIHC cis rs12744310 0.887 rs12047272 chr1:41801943 G/A cg03962019 chr1:41807865 NA 0.39 6.34 0.32 7.17e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs2777491 0.957 rs919961 chr15:41651721 A/G cg18705301 chr15:41695430 NDUFAF1 -0.58 -8.91 -0.43 3.1e-17 Ulcerative colitis; LIHC cis rs10838687 0.800 rs1051006 chr11:47306585 C/T cg26139080 chr11:47293733 MADD -0.42 -5.86 -0.3 1.09e-8 Proinsulin levels; LIHC cis rs4595586 0.545 rs12813151 chr12:39363405 C/G cg26384229 chr12:38710491 ALG10B -0.46 -5.74 -0.3 2.08e-8 Morning vs. evening chronotype; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg07068998 chr1:115259668 NRAS;CSDE1 -0.5 -6.71 -0.34 7.94e-11 Electroencephalogram traits; LIHC cis rs3018712 0.508 rs4930582 chr11:68411104 C/T cg16797656 chr11:68205561 LRP5 -0.44 -5.83 -0.3 1.28e-8 Total body bone mineral density; LIHC cis rs644799 0.542 rs10831416 chr11:95467220 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.76 11.75 0.54 5.28e-27 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs17685 0.753 rs1104879 chr7:75685568 C/T cg04592579 chr7:75616294 TMEM120A 0.39 6.79 0.34 5.04e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9309473 0.950 rs11126412 chr2:73887634 A/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.31 -0.32 8.78e-10 Metabolite levels; LIHC cis rs9359856 0.564 rs17292425 chr6:90372128 A/G cg13799429 chr6:90582589 CASP8AP2 -0.64 -5.93 -0.31 7.57e-9 Bipolar disorder; LIHC cis rs6596100 0.538 rs17516673 chr5:132196711 C/T cg02081065 chr5:132209139 LEAP2 0.29 6.3 0.32 9.39e-10 Breast cancer; LIHC cis rs644148 0.967 rs613876 chr19:44968788 T/C cg15540054 chr19:45004280 ZNF180 -0.78 -11.58 -0.53 2.17e-26 Personality dimensions; LIHC cis rs11663156 0.804 rs12965192 chr18:50906825 C/A cg24270629 chr18:50823537 DCC 0.5 7.09 0.36 7.79e-12 Intelligence (multi-trait analysis); LIHC cis rs7614311 0.689 rs2276863 chr3:63849043 C/A cg22134162 chr3:63841271 THOC7 -0.56 -6.32 -0.32 8.02e-10 Lung function (FVC);Lung function (FEV1); LIHC cis rs1538970 0.924 rs4660855 chr1:45899795 A/G cg24296786 chr1:45957014 TESK2 -0.5 -7.17 -0.36 4.59e-12 Platelet count; LIHC cis rs72627123 0.867 rs112464051 chr14:74483975 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.56 0.46 2.44e-19 Morning vs. evening chronotype; LIHC cis rs4746818 1.000 rs7901617 chr10:70904063 C/T cg11621586 chr10:70884670 VPS26A 0.87 14.24 0.61 1.83e-36 Left atrial antero-posterior diameter; LIHC cis rs7172677 0.732 rs1867147 chr15:75363357 C/T cg09165964 chr15:75287851 SCAMP5 0.45 6.24 0.32 1.29e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2842992 0.789 rs6908680 chr6:160218209 G/T cg11366901 chr6:160182831 ACAT2 0.93 15.37 0.64 6.85e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs9911578 1.000 rs4636974 chr17:56965373 C/G cg12560992 chr17:57184187 TRIM37 0.98 17.78 0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs9921222 0.521 rs62032884 chr16:363415 C/T cg00101154 chr16:420108 MRPL28 -0.61 -8.36 -0.41 1.6e-15 Bone mineral density (spine);Bone mineral density; LIHC cis rs9549328 0.837 rs9549618 chr13:113628648 G/A cg08890338 chr13:113700818 MCF2L -0.36 -5.75 -0.3 2.03e-8 Systolic blood pressure; LIHC cis rs2834256 0.924 rs2834244 chr21:35035012 T/A cg14850771 chr21:34775459 IFNGR2 0.42 6.49 0.33 2.94e-10 Red cell distribution width; LIHC cis rs1559088 0.847 rs7255968 chr19:33601902 A/T cg27124370 chr19:33622961 WDR88 0.53 8.29 0.41 2.56e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg11644478 chr21:40555479 PSMG1 0.44 6.92 0.35 2.23e-11 Cognitive function; LIHC cis rs986417 0.901 rs10483726 chr14:61039476 A/G cg27398547 chr14:60952738 C14orf39 0.8 9.05 0.44 1.13e-17 Gut microbiota (bacterial taxa); LIHC trans rs2018683 0.899 rs10479816 chr7:28978021 G/A cg19402173 chr7:128379420 CALU -0.4 -6.36 -0.33 6.29e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; LIHC cis rs7095944 0.614 rs11245354 chr10:126450125 C/A cg20435097 chr10:126320824 FAM53B 0.37 6.29 0.32 9.5e-10 Asthma; LIHC trans rs11088226 0.581 rs1967870 chr21:33882858 A/G cg09050820 chr6:167586206 TCP10L2 0.48 7.47 0.37 6.8e-13 Gastritis; LIHC cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg23758822 chr17:41437982 NA 0.93 17.8 0.69 1.27e-50 Menopause (age at onset); LIHC cis rs1799949 0.965 rs4239149 chr17:41328095 A/G cg23758822 chr17:41437982 NA -0.97 -18.68 -0.71 3.55e-54 Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10292851 chr8:101572103 ANKRD46 0.45 6.17 0.32 1.88e-9 Pancreatic cancer; LIHC cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg22618164 chr12:122356400 WDR66 -0.62 -10.98 -0.51 3.26e-24 Mean corpuscular volume; LIHC trans rs61931739 0.500 rs7306435 chr12:34482933 A/G cg26384229 chr12:38710491 ALG10B -0.75 -9.26 -0.45 2.29e-18 Morning vs. evening chronotype; LIHC cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg11764359 chr7:65958608 NA -0.58 -6.06 -0.31 3.62e-9 Diabetic kidney disease; LIHC cis rs6977660 0.607 rs12113916 chr7:19781424 G/T cg07541023 chr7:19748670 TWISTNB 0.49 7.0 0.35 1.34e-11 Thyroid stimulating hormone; LIHC cis rs151997 0.538 rs1345777 chr5:50263788 A/G cg06027927 chr5:50259733 NA -0.52 -6.32 -0.32 7.97e-10 Callous-unemotional behaviour; LIHC cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg13047869 chr3:10149882 C3orf24 0.54 6.49 0.33 2.99e-10 Alzheimer's disease; LIHC cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg22442454 chr1:209979470 IRF6 0.41 6.16 0.32 2.04e-9 Cleft lip with or without cleft palate; LIHC cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg24549020 chr5:56110836 MAP3K1 0.5 6.43 0.33 4.23e-10 Initial pursuit acceleration; LIHC cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg12756686 chr19:29218302 NA 0.44 6.44 0.33 4.13e-10 Methadone dose in opioid dependence; LIHC cis rs7258465 1.000 rs28572537 chr19:18552208 C/T cg10790698 chr19:18539756 SSBP4 -0.37 -7.58 -0.38 3.21e-13 Breast cancer; LIHC cis rs710216 0.957 rs3738514 chr1:43426591 A/G cg03128534 chr1:43423976 SLC2A1 -0.46 -5.79 -0.3 1.64e-8 Red cell distribution width; LIHC cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg13047869 chr3:10149882 C3orf24 0.48 5.96 0.31 6.31e-9 Alzheimer's disease; LIHC cis rs7903847 0.620 rs11189168 chr10:99125769 T/C cg20016023 chr10:99160130 RRP12 -0.39 -6.26 -0.32 1.18e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1005277 0.602 rs1740743 chr10:38519222 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs3806843 0.931 rs13168670 chr5:140146899 T/C cg26395211 chr5:140044315 WDR55 -0.42 -6.18 -0.32 1.78e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs9910055 0.530 rs2269906 chr17:42294337 G/T cg10896456 chr17:42255109 ASB16;C17orf65 -0.38 -6.67 -0.34 1.04e-10 Total body bone mineral density; LIHC cis rs1577917 0.958 rs12202188 chr6:86562700 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.22 -0.41 4.25e-15 Response to antipsychotic treatment; LIHC cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg26566898 chr11:117069891 TAGLN 0.48 7.47 0.37 6.81e-13 Blood protein levels; LIHC cis rs6952808 0.595 rs3778982 chr7:2166233 T/C cg04267008 chr7:1944627 MAD1L1 -0.53 -8.22 -0.41 4.3e-15 Bipolar disorder and schizophrenia; LIHC cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg06238570 chr21:40685208 BRWD1 0.58 6.86 0.35 3.33e-11 Cognitive function; LIHC cis rs3096299 0.685 rs2911244 chr16:89521860 A/G cg00750074 chr16:89608354 SPG7 -0.48 -7.71 -0.38 1.4e-13 Multiple myeloma (IgH translocation); LIHC cis rs6960043 0.818 rs2215383 chr7:15062983 T/C cg19272540 chr7:15055459 NA -0.24 -6.53 -0.33 2.42e-10 Type 2 diabetes; LIHC trans rs916888 0.773 rs199448 chr17:44809001 A/G cg12297030 chr17:43662878 NA -0.64 -6.2 -0.32 1.65e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12889510 chr2:204399188 RAPH1 0.51 6.84 0.35 3.62e-11 Pancreatic cancer; LIHC cis rs7584330 0.910 rs7606177 chr2:238394913 G/C cg14458575 chr2:238380390 NA 0.37 6.03 0.31 4.29e-9 Prostate cancer; LIHC cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg15105969 chr2:36825350 FEZ2 0.47 5.74 0.3 2.11e-8 Height; LIHC cis rs11098499 0.738 rs72918577 chr4:120326701 G/A cg09307838 chr4:120376055 NA 0.79 12.44 0.56 1.47e-29 Corneal astigmatism; LIHC cis rs2576037 0.583 rs641366 chr18:44430326 C/T cg19077165 chr18:44547161 KATNAL2 -0.47 -7.09 -0.36 7.75e-12 Personality dimensions; LIHC cis rs4665809 0.878 rs892448 chr2:26366205 A/G cg04944784 chr2:26401820 FAM59B -0.71 -9.08 -0.44 8.97e-18 Gut microbiome composition (summer); LIHC cis rs10197940 0.510 rs7602715 chr2:152421937 A/G cg06191203 chr2:152266755 RIF1 -0.48 -8.53 -0.42 4.86e-16 Lung cancer; LIHC cis rs6690583 0.623 rs7522239 chr1:85484366 C/T cg22153463 chr1:85462885 MCOLN2 0.46 5.74 0.3 2.06e-8 Serum sulfate level; LIHC cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.76 0.3 1.83e-8 Menopause (age at onset); LIHC cis rs11711311 0.747 rs7638449 chr3:113343646 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.34 -6.08 -0.31 3.13e-9 IgG glycosylation; LIHC cis rs9911578 0.692 rs412000 chr17:56709058 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.54 7.65 0.38 2.03e-13 Intelligence (multi-trait analysis); LIHC cis rs12644436 0.602 rs4693186 chr4:88782841 G/A cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC trans rs11039798 0.925 rs12277669 chr11:48925316 A/T cg15704280 chr7:45808275 SEPT13 0.61 6.33 0.32 7.57e-10 Axial length; LIHC cis rs10847980 0.590 rs58182048 chr12:123287708 C/T cg18912006 chr12:123335444 HIP1R 0.73 7.15 0.36 5.33e-12 Adiponectin levels; LIHC cis rs4906332 1.000 rs55731474 chr14:103878481 G/A cg04998671 chr14:104000505 TRMT61A -0.42 -5.84 -0.3 1.19e-8 Coronary artery disease; LIHC cis rs4819052 0.851 rs7275870 chr21:46671214 C/T cg22633049 chr21:46681294 NA -0.37 -6.34 -0.32 7.23e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs3761218 0.738 rs4815604 chr20:3772913 C/T cg25011176 chr20:3776985 CDC25B -0.41 -5.85 -0.3 1.17e-8 Bipolar disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09439264 chr1:1230073 ACAP3 0.43 6.39 0.33 5.44e-10 Pancreatic cancer; LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg23601095 chr6:26197514 HIST1H3D 0.55 5.83 0.3 1.27e-8 Gout;Renal underexcretion gout; LIHC cis rs1843834 0.634 rs923901 chr2:225477276 A/T cg22509189 chr2:225307070 NA -0.62 -7.82 -0.39 6.44e-14 IgE levels in asthmatics (D.p. specific); LIHC trans rs116095464 0.558 rs7708182 chr5:234788 C/G cg00938859 chr5:1591904 SDHAP3 0.58 7.11 0.36 7.03e-12 Breast cancer; LIHC cis rs11630290 0.518 rs56247655 chr15:64171627 G/A cg12036633 chr15:63758958 NA -0.59 -5.78 -0.3 1.69e-8 Iris characteristics; LIHC cis rs919433 0.617 rs34632716 chr2:198542619 C/T cg03934865 chr2:198174659 NA -0.49 -7.07 -0.36 8.97e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs965469 1.000 rs6051763 chr20:3321616 T/G cg25506879 chr20:3388711 C20orf194 -0.59 -7.07 -0.36 8.66e-12 IFN-related cytopenia; LIHC cis rs13040088 1.000 rs6090155 chr20:61527378 G/A cg23096297 chr20:61557774 DIDO1 0.79 10.56 0.5 9.5e-23 Menopause (age at onset); LIHC trans rs7618501 0.521 rs3733134 chr3:49939503 C/T cg21659725 chr3:3221576 CRBN 0.57 8.26 0.41 3.27e-15 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.933 rs4470197 chr17:28464474 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.15 0.44 5.34e-18 Coffee consumption (cups per day); LIHC cis rs11734570 0.581 rs75356782 chr4:38600053 T/G cg18361445 chr4:38666374 KLF3;FLJ13197 0.52 7.03 0.36 1.09e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs3741404 0.791 rs7112960 chr11:63907079 A/G cg04317338 chr11:64019027 PLCB3 0.49 6.67 0.34 1.05e-10 Platelet count; LIHC cis rs3809863 0.602 rs2317677 chr17:45393407 G/A cg08085267 chr17:45401833 C17orf57 -0.64 -9.98 -0.47 9.21e-21 Glaucoma (primary open-angle); LIHC cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg13397359 chr6:42928475 GNMT 0.64 9.26 0.45 2.33e-18 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs561341 0.941 rs2428341 chr17:30317295 C/T cg20587970 chr11:113659929 NA -0.64 -7.41 -0.37 9.95e-13 Hip circumference adjusted for BMI; LIHC cis rs798554 0.591 rs1713913 chr7:2895627 C/T cg04166393 chr7:2884313 GNA12 0.35 5.72 0.3 2.32e-8 Height; LIHC cis rs9649465 1.000 rs9649465 chr7:123376560 G/A cg03229431 chr7:123269106 ASB15 -0.38 -8.17 -0.4 6.25e-15 Migraine; LIHC trans rs11098499 0.754 rs938056 chr4:120237453 C/T cg25214090 chr10:38739885 LOC399744 0.53 8.61 0.42 2.75e-16 Corneal astigmatism; LIHC cis rs651907 0.557 rs7651406 chr3:101393296 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.97 0.57 1.49e-31 Colorectal cancer; LIHC cis rs1707322 0.752 rs10430105 chr1:46138876 G/A cg03146154 chr1:46216737 IPP 0.57 9.89 0.47 1.96e-20 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg07424592 chr7:64974309 NA 0.81 9.2 0.45 3.52e-18 Diabetic kidney disease; LIHC cis rs2361710 0.704 rs4889979 chr17:78121707 T/A cg09238746 chr17:78121135 EIF4A3 -0.54 -8.21 -0.41 4.54e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; LIHC cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg26913058 chr16:419975 MRPL28 -0.58 -8.87 -0.43 4.07e-17 Bone mineral density (spine);Bone mineral density; LIHC cis rs1712517 0.787 rs1163089 chr10:105043964 G/A cg05636881 chr10:105038444 INA 0.42 6.43 0.33 4.38e-10 Migraine; LIHC cis rs3784262 0.679 rs11071365 chr15:58334126 G/A cg12031962 chr15:58353849 ALDH1A2 -0.35 -6.73 -0.34 7.37e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7772486 0.846 rs2892453 chr6:146377717 C/A cg23711669 chr6:146136114 FBXO30 0.59 10.5 0.49 1.59e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs40363 0.645 rs250631 chr16:3523215 G/C cg00484396 chr16:3507460 NAT15 0.43 7.59 0.38 3.15e-13 Tuberculosis; LIHC cis rs769267 0.930 rs3794990 chr19:19610030 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.98 0.4 2.19e-14 Tonsillectomy; LIHC cis rs17401966 0.931 rs11587854 chr1:10447622 G/A cg15208524 chr1:10270712 KIF1B 0.4 5.8 0.3 1.53e-8 Hepatocellular carcinoma; LIHC cis rs9309473 1.000 rs6707722 chr2:73654363 G/A cg20560298 chr2:73613845 ALMS1 -0.56 -7.09 -0.36 7.86e-12 Metabolite levels; LIHC cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg06238570 chr21:40685208 BRWD1 0.58 6.72 0.34 7.6e-11 Cognitive function; LIHC cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg11279151 chr3:101281821 RG9MTD1 0.39 5.97 0.31 5.91e-9 Colorectal cancer; LIHC cis rs9790314 1.000 rs456611 chr3:161097268 A/G cg04691961 chr3:161091175 C3orf57 -0.45 -7.07 -0.36 8.61e-12 Morning vs. evening chronotype; LIHC cis rs2153535 0.580 rs7341381 chr6:8470537 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.06 0.4 1.29e-14 Motion sickness; LIHC cis rs16958440 0.867 rs80006910 chr18:44696382 C/G cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs2070488 0.861 rs1858740 chr3:38438372 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.89 15.22 0.64 2.66e-40 Electrocardiographic conduction measures; LIHC cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.53 0.56 6.89e-30 Prudent dietary pattern; LIHC cis rs3762637 0.943 rs28372690 chr3:122283095 G/A cg24169773 chr3:122142474 KPNA1 -0.45 -8.86 -0.43 4.49e-17 LDL cholesterol levels; LIHC cis rs797680 0.822 rs1572343 chr1:93616202 T/C cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -5.93 -0.31 7.53e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg09323728 chr8:95962352 TP53INP1 -0.3 -6.43 -0.33 4.38e-10 Type 2 diabetes; LIHC cis rs7208859 0.673 rs11658435 chr17:29228561 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg18867708 chr6:26865862 GUSBL1 -0.5 -7.62 -0.38 2.58e-13 Schizophrenia; LIHC cis rs4689592 0.503 rs11937667 chr4:7057037 C/G cg02503808 chr4:7069936 GRPEL1 -0.76 -10.7 -0.5 3.07e-23 Monocyte percentage of white cells; LIHC cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg05368731 chr17:41323189 NBR1 0.72 12.06 0.55 3.69e-28 Menopause (age at onset); LIHC cis rs10216189 0.967 rs4724700 chr7:5526789 A/G cg05318486 chr7:5553423 FBXL18 -0.54 -7.79 -0.39 8.05e-14 Relative hand skill in reading disability; LIHC cis rs6546550 0.901 rs7419837 chr2:70146625 T/C cg02498382 chr2:70120550 SNRNP27 -0.44 -7.62 -0.38 2.56e-13 Prevalent atrial fibrillation; LIHC cis rs11785400 1.000 rs4266629 chr8:143736635 A/G cg10596483 chr8:143751796 JRK 0.51 8.39 0.41 1.32e-15 Schizophrenia; LIHC cis rs3741404 0.895 rs1860368 chr11:63994692 T/C cg18225595 chr11:63971243 STIP1 -0.66 -10.4 -0.49 3.2800000000000002e-22 Platelet count; LIHC cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg03517284 chr6:25882590 NA -0.61 -8.59 -0.42 3.13e-16 Blood metabolite levels; LIHC cis rs7635838 0.827 rs9826044 chr3:11458075 A/G cg00170343 chr3:11313890 ATG7 0.43 6.66 0.34 1.09e-10 HDL cholesterol; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00777555 chr3:57583074 ARF4 0.48 7.19 0.36 4.08e-12 Pancreatic cancer; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg07478662 chr19:5047466 KDM4B 0.36 6.11 0.31 2.69e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7635838 0.929 rs7638724 chr3:11413387 T/G cg00170343 chr3:11313890 ATG7 0.46 7.32 0.37 1.77e-12 HDL cholesterol; LIHC cis rs9790314 0.846 rs4560315 chr3:160982132 G/T cg03342759 chr3:160939853 NMD3 -0.82 -13.51 -0.59 1.31e-33 Morning vs. evening chronotype; LIHC cis rs739401 0.619 rs10766480 chr11:2961325 G/A cg25174290 chr11:3078921 CARS 0.56 8.53 0.42 4.67e-16 Longevity; LIHC trans rs11098499 0.954 rs34858317 chr4:120387110 A/C cg25214090 chr10:38739885 LOC399744 0.61 9.95 0.47 1.17e-20 Corneal astigmatism; LIHC cis rs7659604 0.502 rs28522256 chr4:122709266 C/T cg19671926 chr4:122722719 EXOSC9 0.56 8.63 0.42 2.3e-16 Type 2 diabetes; LIHC cis rs9399135 0.869 rs9402675 chr6:135325794 C/G cg22676075 chr6:135203613 NA 0.38 6.26 0.32 1.13e-9 Red blood cell count; LIHC cis rs6840360 0.837 rs4696294 chr4:152713089 C/A cg22705602 chr4:152727874 NA 0.33 6.94 0.35 1.97e-11 Intelligence (multi-trait analysis); LIHC cis rs6429082 0.871 rs9662392 chr1:235576949 G/T cg26050004 chr1:235667680 B3GALNT2 -0.41 -6.17 -0.32 1.88e-9 Adiposity; LIHC cis rs10508774 1.000 rs58255751 chr10:32766169 G/A cg01819863 chr10:32635814 EPC1 0.65 6.08 0.31 3.28e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3806843 0.762 rs3756337 chr5:140186438 G/C cg26395211 chr5:140044315 WDR55 -0.4 -5.87 -0.3 1.01e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs6450176 0.625 rs3776726 chr5:53290052 T/A ch.5.1024479R chr5:53302184 ARL15 -0.89 -16.49 -0.67 2.23e-45 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs1552244 0.882 rs13089863 chr3:10032259 G/T cg08888203 chr3:10149979 C3orf24 -0.48 -6.0 -0.31 5.01e-9 Alzheimer's disease; LIHC cis rs12971120 0.891 rs3794953 chr18:72180519 C/T cg25817165 chr18:72167213 CNDP2 -0.71 -12.2 -0.55 1.17e-28 Refractive error; LIHC cis rs5769765 0.865 rs4824108 chr22:50271428 A/G cg26441486 chr22:50317300 CRELD2 -0.34 -5.99 -0.31 5.21e-9 Schizophrenia; LIHC cis rs1003719 0.646 rs2835671 chr21:38581125 T/G cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.23 -0.48 1.3e-21 Eye color traits; LIHC cis rs4474465 0.688 rs10899553 chr11:78265210 A/G cg27205649 chr11:78285834 NARS2 0.47 7.2 0.36 3.84e-12 Alzheimer's disease (survival time); LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs2075165 0.901 rs10908492 chr1:156224795 C/T cg08469215 chr1:156261351 TMEM79 0.36 5.71 0.3 2.42e-8 Tonsillectomy; LIHC cis rs6582630 0.531 rs3850000 chr12:38483752 T/C cg26384229 chr12:38710491 ALG10B 0.69 9.62 0.46 1.47e-19 Drug-induced liver injury (flucloxacillin); LIHC trans rs62103177 0.810 rs62096745 chr18:77619135 A/G cg05926928 chr17:57297772 GDPD1 1.13 11.63 0.53 1.48e-26 Opioid sensitivity; LIHC cis rs35306767 0.855 rs11253465 chr10:897208 A/C cg20503657 chr10:835505 NA 1.03 11.72 0.54 6.64e-27 Eosinophil percentage of granulocytes; LIHC cis rs72781680 0.898 rs56315094 chr2:23941952 T/C cg08917208 chr2:24149416 ATAD2B 0.85 7.76 0.39 1.01e-13 Lymphocyte counts; LIHC cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg11062466 chr8:58055876 NA 0.46 6.53 0.33 2.36e-10 Developmental language disorder (linguistic errors); LIHC cis rs12142240 0.698 rs17361915 chr1:46847321 C/T cg14993813 chr1:46806288 NSUN4 -0.65 -5.89 -0.3 9.4e-9 Menopause (age at onset); LIHC cis rs801193 1.000 rs10252765 chr7:66228732 C/G cg00343986 chr7:65444356 GUSB 0.39 5.73 0.3 2.26e-8 Aortic root size; LIHC cis rs9309473 1.000 rs56154726 chr2:73721767 C/T cg20560298 chr2:73613845 ALMS1 -0.56 -6.5 -0.33 2.87e-10 Metabolite levels; LIHC cis rs2153535 0.580 rs6941771 chr6:8494452 T/G cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg24531977 chr5:56204891 C5orf35 -0.69 -9.87 -0.47 2.26e-20 Initial pursuit acceleration; LIHC cis rs11577318 0.538 rs10902745 chr1:26687070 G/C cg18121669 chr1:26560928 CCDC21 -0.5 -7.56 -0.38 3.72e-13 Granulocyte percentage of myeloid white cells; LIHC cis rs716804 0.621 rs11042717 chr11:10303939 C/T cg01453529 chr11:10209919 SBF2 0.3 5.97 0.31 6.06e-9 Neuroticism; LIHC cis rs712039 0.652 rs2680719 chr17:35811453 C/T cg16670864 chr17:35848621 DUSP14 0.34 5.82 0.3 1.38e-8 Tuberculosis; LIHC cis rs2834188 1.000 rs4408796 chr21:34698741 C/G cg04842828 chr21:34696676 IFNAR1 -0.46 -6.17 -0.32 1.89e-9 Narcolepsy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07030052 chr1:162531143 UAP1 0.49 6.28 0.32 1.04e-9 Lung function (FEV1/FVC); LIHC cis rs6502050 0.835 rs4789672 chr17:80126603 T/C cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs11123170 0.640 rs1015754 chr2:113967990 T/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.49 -6.23 -0.32 1.4e-9 Renal function-related traits (BUN); LIHC cis rs9303401 0.527 rs34835800 chr17:56764990 G/A cg25039879 chr17:56429692 SUPT4H1 0.74 7.81 0.39 6.99e-14 Cognitive test performance; LIHC cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg02290350 chr8:58132656 NA 0.5 10.46 0.49 2.18e-22 Developmental language disorder (linguistic errors); LIHC cis rs9816226 0.618 rs869399 chr3:185826764 C/T cg00760338 chr3:185826511 ETV5 0.98 15.36 0.64 7.13e-41 Obesity;Body mass index; LIHC cis rs10744422 0.800 rs1696320 chr12:123269814 A/G cg07706471 chr12:123319906 HIP1R -0.56 -7.3 -0.37 2.05e-12 Schizophrenia; LIHC cis rs1401999 1.000 rs1402002 chr3:183642794 A/G cg05044414 chr3:183734942 ABCC5 0.32 5.71 0.3 2.44e-8 Anterior chamber depth; LIHC cis rs1336900 0.637 rs35967040 chr1:150555588 A/C cg18016565 chr1:150552671 MCL1 -0.68 -13.54 -0.59 9.95e-34 Blood protein levels; LIHC cis rs7095944 0.644 rs4962694 chr10:126436717 G/T cg08799069 chr10:126477246 METTL10 -0.37 -6.48 -0.33 3.29e-10 Asthma; LIHC cis rs9649213 0.574 rs7789440 chr7:97888798 G/T cg08684580 chr7:98029266 BAIAP2L1 -0.41 -6.29 -0.32 9.6e-10 Prostate cancer (SNP x SNP interaction); LIHC trans rs1005277 0.540 rs1987431 chr10:37988887 T/C cg23533926 chr12:111358616 MYL2 -0.33 -6.52 -0.33 2.54e-10 Extrinsic epigenetic age acceleration; LIHC cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg00750074 chr16:89608354 SPG7 -0.48 -7.95 -0.39 2.83e-14 Multiple myeloma (IgH translocation); LIHC cis rs35110281 0.782 rs1584917 chr21:45042365 A/G cg04455712 chr21:45112962 RRP1B 0.48 8.32 0.41 2.09e-15 Mean corpuscular volume; LIHC cis rs2412488 1.000 rs4864759 chr4:54259408 G/A cg22241045 chr4:54363911 LNX1 -0.45 -7.21 -0.36 3.54e-12 DNA methylation (variation); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26789732 chr8:73449127 KCNB2 -0.33 -6.16 -0.32 2.06e-9 Cognitive function; LIHC cis rs11673344 0.864 rs8107192 chr19:37499627 G/A cg27390819 chr19:37464633 NA -0.51 -6.24 -0.32 1.26e-9 Obesity-related traits; LIHC cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg18404041 chr3:52824283 ITIH1 -0.55 -9.21 -0.45 3.3e-18 Electroencephalogram traits; LIHC cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg07677032 chr17:61819896 STRADA 0.44 6.44 0.33 4.01e-10 Prudent dietary pattern; LIHC trans rs1814175 0.645 rs28436748 chr11:50046422 G/A cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs7568458 0.709 rs56819945 chr2:85755139 C/T cg02493740 chr2:85810744 VAMP5 -0.48 -7.95 -0.39 2.77e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs1580019 0.547 rs56981934 chr7:32535202 C/G cg07520158 chr7:32535189 LSM5;AVL9 0.62 9.18 0.44 4.16e-18 Cognitive ability; LIHC cis rs9916302 0.904 rs10432031 chr17:37397852 G/A cg03013999 chr17:37608204 MED1 0.34 5.77 0.3 1.78e-8 Glomerular filtration rate (creatinine); LIHC cis rs11690935 0.959 rs6759575 chr2:172689068 C/T cg13550731 chr2:172543902 DYNC1I2 -0.91 -17.25 -0.68 2.15e-48 Schizophrenia; LIHC cis rs9325144 0.560 rs7971313 chr12:38653413 A/G cg26384229 chr12:38710491 ALG10B -0.48 -7.41 -0.37 1.03e-12 Morning vs. evening chronotype; LIHC cis rs12413816 0.784 rs35537139 chr10:13768894 G/A cg16485048 chr10:13749193 FRMD4A 0.49 6.69 0.34 9.03e-11 Red cell distribution width; LIHC cis rs2303759 0.874 rs10411630 chr19:49891314 C/A cg22590775 chr19:49891494 CCDC155 0.48 7.86 0.39 5.15e-14 Multiple sclerosis; LIHC cis rs7923837 0.651 rs12355158 chr10:94350681 G/A cg25506282 chr10:94462361 NA 0.34 5.81 0.3 1.45e-8 Body mass index;Multiple sclerosis; LIHC cis rs11122272 0.701 rs2491402 chr1:231494338 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -10.95 -0.51 3.93e-24 Hemoglobin concentration; LIHC cis rs6570726 0.935 rs386344 chr6:145855622 A/G cg23711669 chr6:146136114 FBXO30 0.52 9.05 0.44 1.14e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs7959452 0.590 rs6581889 chr12:69757429 T/C cg22834771 chr12:69754056 YEATS4 -0.53 -9.35 -0.45 1.15e-18 Blood protein levels; LIHC cis rs1008375 1.000 rs4698635 chr4:17630242 C/A cg02297831 chr4:17616191 MED28 0.47 7.22 0.36 3.37e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs3823572 0.542 rs62470448 chr7:133635618 T/A cg03336402 chr7:133662267 EXOC4 0.49 6.06 0.31 3.53e-9 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08836144 chr11:66886918 KDM2A 0.45 6.48 0.33 3.23e-10 Pancreatic cancer; LIHC cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg16497277 chr3:49208875 KLHDC8B -0.49 -6.25 -0.32 1.25e-9 Menarche (age at onset); LIHC cis rs7131987 0.650 rs7301188 chr12:29455391 C/T cg05697976 chr12:29376483 FAR2 0.29 5.99 0.31 5.43e-9 QT interval; LIHC cis rs916888 0.821 rs70600 chr17:44860021 C/T cg01570182 chr17:44337453 NA 1.0 9.86 0.47 2.34e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4843747 0.671 rs72818540 chr16:88078988 C/T cg00677901 chr16:88017247 BANP 0.55 8.14 0.4 7.19e-15 Menopause (age at onset); LIHC cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg13397359 chr6:42928475 GNMT 0.68 9.86 0.47 2.47e-20 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04738379 chr15:81282102 MESDC2 -0.5 -6.35 -0.32 6.77e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg27572855 chr1:25598939 RHD 0.4 8.48 0.42 6.71e-16 Plateletcrit;Mean corpuscular volume; LIHC cis rs17685 0.753 rs13240967 chr7:75658197 C/T cg04592579 chr7:75616294 TMEM120A -0.4 -6.97 -0.35 1.64e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9948 0.655 rs17119562 chr2:97381844 G/C cg01990225 chr2:97406019 LMAN2L -0.81 -6.31 -0.32 8.67e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs4638749 0.677 rs6755078 chr2:108818270 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.12 -0.31 2.52e-9 Blood pressure; LIHC cis rs539514 0.516 rs2273996 chr13:76410725 A/G cg04757411 chr13:76259545 LMO7 0.38 5.93 0.31 7.29e-9 Type 1 diabetes; LIHC cis rs16866061 1.000 rs72972378 chr2:225372562 A/G cg12698349 chr2:225449008 CUL3 0.76 13.2 0.58 2e-32 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg16058607 chr15:60298730 NA -0.51 -6.12 -0.31 2.53e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg19318889 chr4:1322082 MAEA 0.63 9.81 0.47 3.45e-20 Longevity; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg25005279 chr10:135113451 TUBGCP2 0.45 6.07 0.31 3.32e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs11623869 0.614 rs11627052 chr14:103863476 A/G cg26031613 chr14:104095156 KLC1 -0.86 -9.2 -0.45 3.68e-18 Bone mineral density; LIHC cis rs892961 0.932 rs7216116 chr17:75405078 C/T cg05865280 chr17:75406074 SEPT9 0.59 10.54 0.5 1.1e-22 Airflow obstruction; LIHC cis rs35110281 0.591 rs230642 chr21:44915533 A/C cg21573476 chr21:45109991 RRP1B 0.45 8.13 0.4 8.15e-15 Mean corpuscular volume; LIHC trans rs79976124 0.797 rs77895756 chr6:66626782 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.8 0.35 4.79e-11 Type 2 diabetes; LIHC cis rs477692 0.905 rs508360 chr10:131424969 A/G cg19680672 chr10:131412579 MGMT -0.42 -6.52 -0.33 2.46e-10 Response to temozolomide; LIHC cis rs7258465 1.000 rs10164323 chr19:18569492 C/T cg10790698 chr19:18539756 SSBP4 -0.36 -7.47 -0.37 6.75e-13 Breast cancer; LIHC cis rs2303745 0.589 rs751599 chr19:17396549 A/G cg04248312 chr19:17393744 ANKLE1 -0.71 -11.28 -0.52 2.75e-25 Systemic lupus erythematosus; LIHC cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg20295408 chr7:1910781 MAD1L1 -0.48 -6.97 -0.35 1.68e-11 Bipolar disorder and schizophrenia; LIHC cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg06697600 chr4:7070879 GRPEL1 -0.65 -10.32 -0.49 6.5600000000000005e-22 Monocyte percentage of white cells; LIHC cis rs9649465 0.551 rs10255400 chr7:123388036 G/A cg03229431 chr7:123269106 ASB15 -0.59 -12.07 -0.55 3.61e-28 Migraine; LIHC cis rs7208859 0.623 rs77544470 chr17:28934550 C/A cg13385521 chr17:29058706 SUZ12P 0.7 6.72 0.34 7.7e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7520050 0.807 rs28378621 chr1:46189554 T/C cg03146154 chr1:46216737 IPP 0.49 8.18 0.4 5.67e-15 Red blood cell count;Reticulocyte count; LIHC cis rs4654899 0.758 rs4457549 chr1:21487231 A/G cg08539965 chr1:21396338 EIF4G3 -0.32 -5.78 -0.3 1.71e-8 Superior frontal gyrus grey matter volume; LIHC cis rs12579753 0.956 rs7309624 chr12:82204266 C/A cg07988820 chr12:82153109 PPFIA2 -0.49 -6.06 -0.31 3.63e-9 Resting heart rate; LIHC cis rs2806561 0.894 rs629107 chr1:23537971 C/T cg19743168 chr1:23544995 NA 0.42 7.94 0.39 2.85e-14 Height; LIHC cis rs57590327 0.503 rs9874184 chr3:81505439 C/T cg07356753 chr3:81810745 GBE1 0.46 6.84 0.35 3.7e-11 Extraversion; LIHC cis rs17331151 0.573 rs77223362 chr3:52865125 G/A cg04865290 chr3:52927548 TMEM110 -0.44 -6.51 -0.33 2.61e-10 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7617773 0.539 rs13069884 chr3:48381148 T/A cg11946769 chr3:48343235 NME6 0.61 7.52 0.38 4.92e-13 Coronary artery disease; LIHC cis rs6952808 0.825 rs4236277 chr7:1942270 C/T cg20295408 chr7:1910781 MAD1L1 -0.52 -7.42 -0.37 9.24e-13 Bipolar disorder and schizophrenia; LIHC cis rs758324 0.891 rs491624 chr5:131270222 A/T cg06307176 chr5:131281290 NA -0.4 -5.82 -0.3 1.33e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs735396 1.000 rs1169306 chr12:121438311 C/T cg02403541 chr12:121454288 C12orf43 0.47 8.22 0.41 4.38e-15 N-glycan levels; LIHC cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg06466757 chr4:1255808 NA 0.35 5.78 0.3 1.64e-8 Obesity-related traits; LIHC cis rs637571 0.522 rs11227368 chr11:65740370 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 8.74 0.43 1.05e-16 Eosinophil percentage of white cells; LIHC cis rs67311347 1.000 rs10510708 chr3:40404770 A/G cg24209194 chr3:40518798 ZNF619 0.42 6.05 0.31 3.85e-9 Renal cell carcinoma; LIHC cis rs9921222 0.521 rs9935268 chr16:381562 G/C cg26913058 chr16:419975 MRPL28 -0.5 -6.85 -0.35 3.37e-11 Bone mineral density (spine);Bone mineral density; LIHC cis rs6570726 0.875 rs368744 chr6:145812622 A/G cg23711669 chr6:146136114 FBXO30 0.5 8.77 0.43 8.86e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs9733 0.628 rs7540874 chr1:150702663 A/C cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs4819052 0.851 rs2236444 chr21:46678226 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.75 0.39 1.08e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2274273 0.840 rs7159144 chr14:55821324 G/A cg04306507 chr14:55594613 LGALS3 0.32 6.08 0.31 3.13e-9 Protein biomarker; LIHC cis rs10504229 0.593 rs74760806 chr8:58024785 C/T cg02290350 chr8:58132656 NA 0.3 6.85 0.35 3.41e-11 Developmental language disorder (linguistic errors); LIHC cis rs10751667 0.666 rs10902255 chr11:967268 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.23 0.48 1.34e-21 Alzheimer's disease (late onset); LIHC cis rs9902453 0.874 rs7213517 chr17:28401740 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.78 -13.73 -0.6 1.82e-34 Coffee consumption (cups per day); LIHC cis rs11319879 1 rs11319879 chr10:94453475 TA/T cg25506282 chr10:94462361 NA 0.43 7.32 0.37 1.79e-12 Sum eosinophil basophil counts;Eosinophil percentage of granulocytes; LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg00106254 chr7:1943704 MAD1L1 -0.42 -6.82 -0.35 4.05e-11 Bipolar disorder and schizophrenia; LIHC cis rs2576037 0.583 rs4890343 chr18:44540969 G/A cg19077165 chr18:44547161 KATNAL2 -0.48 -7.23 -0.36 3.18e-12 Personality dimensions; LIHC cis rs9640161 0.830 rs13307276 chr7:150061525 T/C cg10018233 chr7:150070692 REPIN1 0.67 12.16 0.55 1.6e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.86 0.39 5.1e-14 Prudent dietary pattern; LIHC cis rs9910055 0.573 rs113184718 chr17:42206543 A/T cg19774624 chr17:42201019 HDAC5 0.83 12.62 0.56 2.98e-30 Total body bone mineral density; LIHC cis rs6502050 0.835 rs8073351 chr17:80127625 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs11764590 0.715 rs55810445 chr7:2103739 C/T cg23422044 chr7:1970798 MAD1L1 -0.5 -5.71 -0.3 2.42e-8 Neuroticism; LIHC cis rs12594515 1.000 rs8032361 chr15:45988553 T/C cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.71e-10 Waist circumference;Weight; LIHC cis rs769267 0.895 rs1000237 chr19:19518316 T/A cg03709012 chr19:19516395 GATAD2A 1.01 18.05 0.7 1.22e-51 Tonsillectomy; LIHC cis rs17826219 0.706 rs8075357 chr17:29057197 A/C cg14067834 chr17:29058358 SUZ12P 0.68 6.77 0.34 5.54e-11 Body mass index; LIHC cis rs9328573 0.967 rs2082859 chr15:100509132 C/G cg09918751 chr15:100517450 ADAMTS17 0.43 6.43 0.33 4.18e-10 Urate levels in lean individuals; LIHC cis rs4819052 0.851 rs2838864 chr21:46711474 A/T cg19498844 chr21:46707878 POFUT2;LOC642852 -0.72 -11.46 -0.53 5.73e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12824058 0.549 rs4759453 chr12:130824565 C/G cg23887609 chr12:130822674 PIWIL1 0.41 6.01 0.31 4.83e-9 Menopause (age at onset); LIHC cis rs9303401 0.614 rs3887355 chr17:56538639 T/C cg25039879 chr17:56429692 SUPT4H1 0.75 8.41 0.41 1.1e-15 Cognitive test performance; LIHC cis rs2180341 1.000 rs3798852 chr6:127636733 A/G cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs17021463 0.643 rs17311521 chr4:95298060 A/G cg11021082 chr4:95130006 SMARCAD1 -0.41 -6.88 -0.35 2.88e-11 Testicular germ cell tumor; LIHC cis rs986417 0.711 rs2224409 chr14:60957216 C/T cg27398547 chr14:60952738 C14orf39 0.77 8.62 0.42 2.44e-16 Gut microbiota (bacterial taxa); LIHC cis rs6952808 0.792 rs2056481 chr7:1955435 A/G cg21782813 chr7:2030301 MAD1L1 0.47 7.77 0.39 9.25e-14 Bipolar disorder and schizophrenia; LIHC cis rs1707322 0.717 rs1135850 chr1:46093692 G/A cg06784218 chr1:46089804 CCDC17 0.42 7.59 0.38 3.17e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs933688 0.938 rs7708782 chr5:90718517 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.37 0.66 6.68e-45 Smoking behavior; LIHC cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.84 0.47 2.86e-20 Electroencephalogram traits; LIHC cis rs17376456 0.569 rs10057664 chr5:93182274 C/T cg25358565 chr5:93447407 FAM172A -0.79 -7.63 -0.38 2.33e-13 Diabetic retinopathy; LIHC cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 6.22 0.32 1.45e-9 Electroencephalogram traits; LIHC cis rs3008870 0.920 rs3008860 chr1:67391003 G/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.45 0.66 3.47e-45 Lymphocyte percentage of white cells; LIHC cis rs7027203 0.828 rs4744287 chr9:96585567 A/G cg14396892 chr9:96623032 NA 0.33 6.46 0.33 3.6e-10 DNA methylation (variation); LIHC cis rs12478296 0.786 rs72620862 chr2:243044787 T/C cg18898632 chr2:242989856 NA -0.57 -7.72 -0.39 1.32e-13 Obesity-related traits; LIHC cis rs6461049 0.608 rs3800923 chr7:2184673 A/G cg21782813 chr7:2030301 MAD1L1 0.34 5.86 0.3 1.1e-8 Schizophrenia; LIHC cis rs6964587 0.869 rs10241720 chr7:91527367 G/T cg17063962 chr7:91808500 NA -0.96 -17.88 -0.7 5.74e-51 Breast cancer; LIHC cis rs7520050 0.771 rs4660882 chr1:46116292 C/T cg03146154 chr1:46216737 IPP 0.5 8.54 0.42 4.4e-16 Red blood cell count;Reticulocyte count; LIHC cis rs17125944 0.505 rs76219229 chr14:53178346 G/A cg13660082 chr14:53194042 PSMC6 -0.44 -7.65 -0.38 2.06e-13 Alzheimer's disease (late onset); LIHC cis rs67311347 0.911 rs6775936 chr3:40377399 T/G cg09455208 chr3:40491958 NA 0.33 6.53 0.33 2.33e-10 Renal cell carcinoma; LIHC cis rs1538970 0.924 rs1007858 chr1:45912005 C/T cg05343316 chr1:45956843 TESK2 0.59 8.53 0.42 4.84e-16 Platelet count; LIHC cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg27170947 chr2:26402098 FAM59B -0.66 -8.28 -0.41 2.74e-15 Gut microbiome composition (summer); LIHC cis rs243505 0.762 rs1019218 chr7:148488964 C/T cg09806900 chr7:148480153 CUL1 0.45 6.7 0.34 8.77e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 12.89 0.57 2.95e-31 Alzheimer's disease; LIHC cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg00656387 chr3:40428638 ENTPD3 -0.43 -7.18 -0.36 4.28e-12 Renal cell carcinoma; LIHC cis rs2019216 1.000 rs3751916 chr17:21909270 T/C cg22648282 chr17:21454238 C17orf51 -0.36 -6.33 -0.32 7.65e-10 Pelvic organ prolapse; LIHC cis rs9658691 0.607 rs9658786 chr10:90776349 A/G cg03111039 chr10:90751583 FAS;ACTA2 0.71 5.74 0.3 2.06e-8 Mosquito bite size; LIHC cis rs7772486 0.790 rs9376971 chr6:146259505 C/T cg23711669 chr6:146136114 FBXO30 -0.64 -11.17 -0.52 6.66e-25 Lobe attachment (rater-scored or self-reported); LIHC trans rs61931739 0.500 rs7979240 chr12:34509026 C/T cg26384229 chr12:38710491 ALG10B 0.75 9.49 0.46 4.22e-19 Morning vs. evening chronotype; LIHC cis rs10088262 0.629 rs12549683 chr8:124798276 G/C cg20713898 chr8:124780851 FAM91A1 -0.54 -7.3 -0.37 2.07e-12 Pancreatic cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05644321 chr20:20693493 RALGAPA2 0.46 7.76 0.39 9.67e-14 Pancreatic cancer; LIHC cis rs9457247 0.534 rs9347170 chr6:167405187 C/T cg23791538 chr6:167370224 RNASET2 0.76 14.19 0.61 2.9e-36 Crohn's disease; LIHC cis rs332507 0.789 rs13097459 chr3:124398112 C/T cg05980111 chr3:124395277 KALRN 0.45 6.99 0.35 1.49e-11 Plateletcrit; LIHC cis rs4820539 1.000 rs756631 chr22:23463183 A/G cg14186256 chr22:23484241 RTDR1 0.97 20.63 0.74 5.06e-62 Bone mineral density; LIHC cis rs2404602 0.536 rs12915248 chr15:76765615 A/T cg03037974 chr15:76606532 NA 0.74 14.59 0.62 7.65e-38 Blood metabolite levels; LIHC cis rs7208859 0.623 rs8075341 chr17:29136565 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12586317 0.511 rs113770696 chr14:35444383 C/T cg16230307 chr14:35515116 FAM177A1 0.77 12.8 0.57 6.22e-31 Psoriasis; LIHC cis rs3796352 1.000 rs35849389 chr3:53005235 A/G cg04865290 chr3:52927548 TMEM110 -0.51 -5.9 -0.3 8.82e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs7927592 0.763 rs11822059 chr11:68300822 T/G cg01657329 chr11:68192670 LRP5 -0.51 -7.44 -0.37 8.07e-13 Total body bone mineral density; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg02128981 chr11:58904901 NA 0.5 6.3 0.32 9.36e-10 Lung function (FEV1); LIHC cis rs875971 0.862 rs778686 chr7:65835910 C/T cg18876405 chr7:65276391 NA 0.35 6.44 0.33 4.17e-10 Aortic root size; LIHC cis rs7843479 1.000 rs67385415 chr8:21853733 T/C cg17168535 chr8:21777572 XPO7 0.44 6.92 0.35 2.3e-11 Mean corpuscular volume; LIHC cis rs2933343 0.761 rs789225 chr3:128600229 G/A cg24203234 chr3:128598194 ACAD9 0.44 6.18 0.32 1.78e-9 IgG glycosylation; LIHC cis rs2845885 0.793 rs57779243 chr11:63882363 G/T cg24431193 chr11:63883947 FLRT1;MACROD1 0.72 10.74 0.5 2.22e-23 Body mass index; LIHC cis rs7116495 0.867 rs510925 chr11:71809500 C/T cg10381502 chr11:71823885 C11orf51 0.94 8.64 0.42 2.15e-16 Severe influenza A (H1N1) infection; LIHC cis rs6598163 0.517 rs10902453 chr12:132297091 G/T cg10319629 chr12:132285459 NA -0.43 -7.53 -0.38 4.66e-13 Migraine; LIHC cis rs1005277 0.579 rs2472173 chr10:38374638 G/A cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs9467773 1.000 rs1321481 chr6:26538210 A/T cg09904177 chr6:26538194 HMGN4 0.66 13.73 0.6 1.84e-34 Intelligence (multi-trait analysis); LIHC cis rs881375 0.715 rs10985073 chr9:123643855 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.4 0.33 5.27e-10 Rheumatoid arthritis; LIHC cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg11890956 chr21:40555474 PSMG1 1.04 14.42 0.61 3.75e-37 Cognitive function; LIHC cis rs921968 0.612 rs573555 chr2:219348888 A/C cg18887096 chr2:219472410 PLCD4 0.38 6.54 0.33 2.21e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7224737 1.000 rs9889640 chr17:40293497 C/T cg00647820 chr17:40259828 DHX58 -0.28 -5.91 -0.3 8.35e-9 Fibrinogen levels; LIHC cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg06873352 chr17:61820015 STRADA 0.72 12.8 0.57 6.66e-31 Prudent dietary pattern; LIHC cis rs4808199 0.895 rs4808196 chr19:19476520 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.48 6.87 0.35 3.02e-11 Nonalcoholic fatty liver disease; LIHC cis rs7086627 0.515 rs11202960 chr10:82209807 G/A cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs2153535 0.580 rs1335636 chr6:8465047 T/C cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg00149659 chr3:10157352 C3orf10 0.61 6.71 0.34 7.86e-11 Alzheimer's disease; LIHC cis rs1670533 0.932 rs6599276 chr4:1056827 T/C cg27284194 chr4:1044797 NA 0.59 8.74 0.43 1.06e-16 Recombination rate (females); LIHC cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg20607798 chr8:58055168 NA 0.49 6.07 0.31 3.33e-9 Developmental language disorder (linguistic errors); LIHC cis rs1008375 1.000 rs9291659 chr4:17662360 A/C cg16339924 chr4:17578868 LAP3 0.41 5.91 0.3 8.45e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg08645402 chr16:4508243 NA 0.41 7.8 0.39 7.39e-14 Schizophrenia; LIHC cis rs7520050 0.966 rs4076006 chr1:46438076 C/T cg03146154 chr1:46216737 IPP -0.38 -6.26 -0.32 1.17e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2180341 1.000 rs13218061 chr6:127653758 G/A cg27446573 chr6:127587934 RNF146 1.03 15.98 0.65 2.57e-43 Breast cancer; LIHC cis rs6964587 0.839 rs6950538 chr7:91417816 T/C cg17063962 chr7:91808500 NA 0.96 17.29 0.68 1.42e-48 Breast cancer; LIHC cis rs9303401 0.659 rs35828828 chr17:56718205 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.41 0.59 2.97e-33 Cognitive test performance; LIHC cis rs780094 0.544 rs780108 chr2:27684957 T/C cg22903471 chr2:27725779 GCKR -0.45 -7.56 -0.38 3.71e-13 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs13088645 0.652 rs13074557 chr3:134153526 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.38 6.83 0.35 4.01e-11 Coronary artery disease; LIHC cis rs9473924 0.954 rs9463653 chr6:50835180 A/G cg14470998 chr6:50812995 TFAP2B 0.44 6.57 0.33 1.86e-10 Body mass index; LIHC cis rs1348850 0.567 rs880899 chr2:178532416 A/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.62 8.16 0.4 6.3e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs4908768 0.501 rs7518608 chr1:8557320 C/G cg20416874 chr1:8611966 RERE -0.68 -14.36 -0.61 6.45e-37 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1018836 0.828 rs7006279 chr8:91605364 A/G cg16814680 chr8:91681699 NA -0.56 -8.94 -0.44 2.47e-17 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs6723226 0.766 rs398290 chr2:32503526 T/C cg02381751 chr2:32503542 YIPF4 0.79 11.92 0.54 1.2100000000000001e-27 Intelligence (multi-trait analysis); LIHC cis rs17854409 1.000 rs17854409 chr20:61491494 T/C cg06598544 chr20:61472147 COL9A3 -0.84 -7.72 -0.39 1.31e-13 Obesity-related traits; LIHC cis rs910316 1.000 rs876402 chr14:75601862 C/T cg08847533 chr14:75593920 NEK9 -0.88 -19.67 -0.73 3.6e-58 Height; LIHC cis rs6831352 0.877 rs29001183 chr4:100056539 C/T cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs12477438 0.520 rs2964969 chr2:99782811 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.89 15.73 0.65 2.41e-42 Chronic sinus infection; LIHC cis rs3748682 0.731 rs3891572 chr1:38298876 C/T cg12658694 chr1:38397304 INPP5B 0.43 5.92 0.3 7.76e-9 Hypothyroidism; LIHC trans rs1476670 0.565 rs2428965 chr1:44502909 A/G cg20980879 chr20:33128552 DYNLRB1 0.35 6.43 0.33 4.33e-10 Eotaxin levels; LIHC cis rs4853525 0.522 rs1860167 chr2:191582387 G/A cg10560079 chr2:191398806 TMEM194B -0.42 -6.0 -0.31 5.15e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells; LIHC trans rs3858145 0.588 rs731063 chr10:70043190 A/G cg04882175 chr6:131122610 NA 0.49 6.14 0.32 2.29e-9 Optic nerve measurement (disc area);Optic cup area;Optic nerve measurement (cup area); LIHC cis rs1048238 0.506 rs12039892 chr1:16167974 A/G cg00529422 chr1:16285251 ZBTB17 -0.34 -6.45 -0.33 3.71e-10 Systolic blood pressure; LIHC trans rs116095464 0.558 rs7713524 chr5:276200 C/T cg00938859 chr5:1591904 SDHAP3 -0.49 -6.42 -0.33 4.64e-10 Breast cancer; LIHC cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg04944784 chr2:26401820 FAM59B 0.72 9.21 0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs2153535 0.580 rs7743686 chr6:8526111 A/G cg21535247 chr6:8435926 SLC35B3 0.65 8.63 0.42 2.43e-16 Motion sickness; LIHC trans rs916888 0.773 rs199443 chr17:44819565 C/T cg16836995 chr17:43662488 NA -0.74 -7.65 -0.38 2e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs10876993 0.784 rs10083154 chr12:58020933 G/A cg04478727 chr12:58166393 METTL1;FAM119B 0.42 5.77 0.3 1.79e-8 Celiac disease or Rheumatoid arthritis; LIHC cis rs796364 0.755 rs6739563 chr2:201134216 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 0.58 6.32 0.32 7.98e-10 Schizophrenia; LIHC cis rs5769707 0.632 rs135877 chr22:50014002 A/G cg01652190 chr22:50026171 C22orf34 -0.33 -7.49 -0.38 6e-13 Monocyte count;Monocyte percentage of white cells; LIHC trans rs9858542 0.953 rs9824092 chr3:49674147 C/G cg21659725 chr3:3221576 CRBN -0.59 -6.61 -0.34 1.5e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs611744 0.839 rs672552 chr8:109164223 A/G cg18478394 chr8:109455254 TTC35 0.39 6.66 0.34 1.1e-10 Dupuytren's disease; LIHC cis rs7833790 0.636 rs12544174 chr8:82731477 G/A cg17211192 chr8:82754475 SNX16 -0.58 -10.57 -0.5 8.77e-23 Diastolic blood pressure; LIHC cis rs3749237 0.595 rs4855839 chr3:49507847 G/A cg03060546 chr3:49711283 APEH 0.6 9.81 0.47 3.63e-20 Resting heart rate; LIHC cis rs6061231 0.958 rs2427304 chr20:60953584 G/A cg03945807 chr20:60948434 NA 0.44 6.81 0.35 4.32e-11 Colorectal cancer; LIHC cis rs875971 0.660 rs801190 chr7:66033033 C/T cg11764359 chr7:65958608 NA -0.72 -10.98 -0.51 3.13e-24 Aortic root size; LIHC cis rs2576037 0.526 rs564113 chr18:44364389 A/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.49 -7.26 -0.37 2.56e-12 Personality dimensions; LIHC cis rs67311347 0.955 rs11719205 chr3:40417258 G/A cg09455208 chr3:40491958 NA 0.34 6.77 0.34 5.69e-11 Renal cell carcinoma; LIHC cis rs10876993 0.890 rs1082502 chr12:58035706 C/T cg18357645 chr12:58087776 OS9 0.5 8.19 0.4 5.38e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs2016586 0.895 rs4821437 chr22:36113450 T/A cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 7.96e-10 Body mass index; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25430094 chr5:42423577 GHR 0.44 6.68 0.34 9.94e-11 Lung function (FEV1/FVC); LIHC cis rs970821 0.667 rs2891799 chr8:124744660 A/G cg00283535 chr8:124749564 ANXA13 0.42 7.88 0.39 4.47e-14 Breast cancer; LIHC cis rs35110281 0.782 rs1454651 chr21:45012476 A/G cg01579765 chr21:45077557 HSF2BP -0.33 -6.15 -0.32 2.13e-9 Mean corpuscular volume; LIHC cis rs10883723 0.773 rs2296587 chr10:104245588 G/A cg22532475 chr10:104410764 TRIM8 -0.37 -6.06 -0.31 3.63e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs12500138 0.557 rs56859187 chr4:166182792 A/G cg25064052 chr4:166216151 KLHL2 -0.65 -6.01 -0.31 4.63e-9 Cognitive function; LIHC cis rs4700695 0.534 rs153395 chr5:65426669 T/A cg21114390 chr5:65439923 SFRS12 -0.51 -5.83 -0.3 1.29e-8 Facial morphology (factor 19); LIHC cis rs4319547 0.956 rs10744275 chr12:123048618 A/G cg23029597 chr12:123009494 RSRC2 -0.52 -7.42 -0.37 9.14e-13 Body mass index; LIHC cis rs72781680 0.821 rs17038360 chr2:24095798 A/G cg08917208 chr2:24149416 ATAD2B 0.64 6.55 0.33 2.09e-10 Lymphocyte counts; LIHC cis rs372883 0.600 rs1312254 chr21:30695401 A/G cg24692254 chr21:30365293 RNF160 -0.53 -6.64 -0.34 1.21e-10 Pancreatic cancer; LIHC trans rs4290604 0.748 rs7594554 chr2:238065981 A/G cg15676719 chr1:167598521 RCSD1 -0.48 -6.23 -0.32 1.34e-9 Asthma; LIHC cis rs2617583 0.967 rs2550948 chr5:1450444 C/T cg07151155 chr5:1473589 LPCAT1 -0.4 -6.23 -0.32 1.4e-9 Breast cancer; LIHC cis rs6424115 1.000 rs2256179 chr1:24132305 A/G cg15997130 chr1:24165203 NA -0.47 -9.78 -0.47 4.55e-20 Immature fraction of reticulocytes; LIHC cis rs2153535 0.580 rs9406172 chr6:8515464 T/A cg07606381 chr6:8435919 SLC35B3 0.8 11.77 0.54 4.4e-27 Motion sickness; LIHC cis rs9473924 0.542 rs36093098 chr6:50833931 G/A cg14470998 chr6:50812995 TFAP2B 0.99 11.3 0.52 2.18e-25 Body mass index; LIHC cis rs8060686 0.545 rs55897859 chr16:68286748 G/C cg05110241 chr16:68378359 PRMT7 -0.62 -6.87 -0.35 3.08e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg21448741 chr8:58168803 NA 0.37 6.9 0.35 2.48e-11 Developmental language disorder (linguistic errors); LIHC cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs6714710 0.603 rs7583868 chr2:98588372 C/A cg26665480 chr2:98280029 ACTR1B 0.43 6.01 0.31 4.65e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs1023500 0.596 rs5751209 chr22:42451603 A/G cg05082376 chr22:42548792 NA -0.4 -5.89 -0.3 9.43e-9 Schizophrenia; LIHC cis rs7107174 0.892 rs2512540 chr11:77979299 A/G cg02023728 chr11:77925099 USP35 0.5 9.52 0.46 3.1400000000000002e-19 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg09455208 chr3:40491958 NA 0.41 8.14 0.4 7.62e-15 Renal cell carcinoma; LIHC cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg15691649 chr6:25882328 NA 0.49 6.81 0.35 4.49e-11 Blood metabolite levels; LIHC cis rs9486715 1.000 rs9486715 chr6:97059769 A/C cg18709589 chr6:96969512 KIAA0776 -0.36 -6.17 -0.32 1.88e-9 Headache; LIHC cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.58 11.01 0.51 2.54e-24 Prudent dietary pattern; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25328417 chr13:50655384 DLEU1;DLEU2 0.42 6.21 0.32 1.56e-9 Cognitive function; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg12879381 chr18:12326166 TUBB6 0.47 6.22 0.32 1.44e-9 Hepatitis; LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs690037 0.528 rs568833 chr3:16367836 C/T cg23474789 chr3:16306055 DPH3;OXNAD1 -0.43 -6.03 -0.31 4.3e-9 Optic nerve measurement (cup-to-disc ratio);Optic nerve measurement (cup area); LIHC cis rs6430585 0.528 rs895285 chr2:136710554 A/G cg07305463 chr2:136567211 LCT -0.38 -5.85 -0.3 1.18e-8 Corneal structure; LIHC cis rs62158211 0.826 rs62158168 chr2:114078381 C/G cg17784749 chr2:114082611 LOC440839 0.65 7.74 0.39 1.1e-13 Sleep duration (oversleepers vs undersleepers);Sleep traits (multi-trait analysis);Sleep duration; LIHC cis rs2842992 0.915 rs1322427 chr6:160075454 C/A cg19482086 chr6:160211437 TCP1;MRPL18 0.7 11.58 0.53 2.22e-26 Age-related macular degeneration (geographic atrophy); LIHC cis rs7520050 0.966 rs6662641 chr1:46571509 T/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.4 5.9 0.3 8.58e-9 Red blood cell count;Reticulocyte count; LIHC cis rs1005277 0.579 rs1780138 chr10:38501654 A/G cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.59 0.56 4.01e-30 Prudent dietary pattern; LIHC cis rs11122272 0.735 rs2790878 chr1:231534390 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -9.86 -0.47 2.42e-20 Hemoglobin concentration; LIHC trans rs4843747 0.671 rs9921236 chr16:88117015 G/T cg09572067 chr16:29127029 RRN3P2 0.52 8.28 0.41 2.88e-15 Menopause (age at onset); LIHC cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg08280861 chr8:58055591 NA 0.55 6.38 0.33 5.82e-10 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.954 rs12510138 chr4:120423935 C/G cg09307838 chr4:120376055 NA 0.77 12.46 0.56 1.26e-29 Corneal astigmatism; LIHC cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs634534 0.622 rs593525 chr11:65727799 T/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.45 7.02 0.35 1.18e-11 Sum eosinophil basophil counts;Eosinophil counts; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08836144 chr11:66886918 KDM2A 0.56 7.41 0.37 1.02e-12 Hepatitis; LIHC trans rs1875517 0.510 rs11721241 chr3:117329656 A/C cg19819135 chr1:70710422 SFRS11 0.33 6.11 0.31 2.76e-9 Waist circumference; LIHC cis rs9309473 1.000 rs58603761 chr2:73726605 A/G cg20560298 chr2:73613845 ALMS1 -0.56 -6.93 -0.35 2.04e-11 Metabolite levels; LIHC cis rs1144333 1.000 rs5745542 chr1:76365073 C/G cg22875332 chr1:76189707 ACADM 0.4 6.22 0.32 1.47e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs10911363 0.570 rs2702204 chr1:183457396 A/G cg09173681 chr1:183549694 NCF2 0.54 9.49 0.46 4.09e-19 Systemic lupus erythematosus; LIHC cis rs7520050 0.966 rs7556615 chr1:46461369 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.43 6.34 0.32 7.42e-10 Red blood cell count;Reticulocyte count; LIHC cis rs7131987 0.650 rs10843384 chr12:29472409 C/T cg00204748 chr12:29376779 FAR2 0.4 7.47 0.37 6.78e-13 QT interval; LIHC cis rs611744 0.647 rs587340 chr8:109246032 C/A cg18478394 chr8:109455254 TTC35 0.41 7.01 0.35 1.28e-11 Dupuytren's disease; LIHC cis rs2576037 0.583 rs646128 chr18:44397691 A/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.83 -0.3 1.31e-8 Personality dimensions; LIHC trans rs6489882 0.510 rs61478890 chr12:113364375 A/G cg10175203 chr3:128143634 NA 0.39 6.39 0.33 5.57e-10 Chronic lymphocytic leukemia; LIHC cis rs5769707 0.609 rs135861 chr22:49998118 A/G cg07959070 chr22:50026188 C22orf34 -0.33 -8.02 -0.4 1.72e-14 Monocyte count;Monocyte percentage of white cells; LIHC cis rs5758659 1.000 rs134869 chr22:42652074 G/A cg19513890 chr22:42538836 CYP2D7P1 -0.38 -7.45 -0.37 7.64e-13 Cognitive function; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26195366 chr10:102242535 WNT8B -0.43 -6.16 -0.32 2.06e-9 Cognitive function; LIHC cis rs5758511 0.680 rs5758686 chr22:42655377 G/T cg20195005 chr22:42527684 CYP2D6 0.31 5.75 0.3 1.94e-8 Birth weight; LIHC cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs2439831 1.000 rs689647 chr15:43762196 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.59 0.59 6.27e-34 Lung cancer in ever smokers; LIHC cis rs847649 0.692 rs1541519 chr7:102466741 G/T cg18108683 chr7:102477205 FBXL13 -0.52 -8.01 -0.4 1.78e-14 Morning vs. evening chronotype; LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg11494091 chr17:61959527 GH2 0.36 6.1 0.31 2.85e-9 Height; LIHC cis rs992157 0.732 rs10932771 chr2:219170236 A/T cg00012203 chr2:219082015 ARPC2 0.82 13.3 0.58 8.21e-33 Colorectal cancer; LIHC cis rs10857712 0.703 rs1056521 chr10:135235890 T/C cg19623624 chr10:135278901 LOC619207 -0.45 -6.97 -0.35 1.65e-11 Systemic lupus erythematosus; LIHC cis rs6964587 0.626 rs9008 chr7:91502407 C/G cg17063962 chr7:91808500 NA -0.61 -11.01 -0.51 2.45e-24 Breast cancer; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00611675 chr8:128748464 MYC 0.41 6.05 0.31 3.71e-9 Lung function (FEV1/FVC); LIHC cis rs7904368 1.000 rs7904368 chr10:16858587 C/T cg14835575 chr10:16859367 RSU1 0.62 8.98 0.44 1.89e-17 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs8049603 0.945 rs3169494 chr16:23076172 A/G cg16484020 chr16:23217411 SCNN1G -0.26 -5.74 -0.3 2.08e-8 Multiple sclerosis; LIHC cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg06481639 chr22:41940642 POLR3H -0.69 -7.07 -0.36 8.6e-12 Vitiligo; LIHC cis rs597539 0.652 rs514833 chr11:68657734 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.92 0.51 5.04e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs2645694 0.626 rs2703121 chr4:77822328 C/G cg03477792 chr4:77819574 ANKRD56 0.59 8.6 0.42 2.89e-16 Emphysema distribution in smoking; LIHC trans rs7613875 0.580 rs12634780 chr3:50043341 A/T cg21659725 chr3:3221576 CRBN -0.55 -8.19 -0.4 5.35e-15 Body mass index; LIHC cis rs703842 1.000 rs10877015 chr12:58167788 A/G cg18357645 chr12:58087776 OS9 -0.45 -6.85 -0.35 3.48e-11 Multiple sclerosis; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg18263451 chr1:25573180 C1orf63 -0.42 -6.04 -0.31 4.11e-9 Immature fraction of reticulocytes; LIHC cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg08677398 chr8:58056175 NA 0.38 5.74 0.3 2.11e-8 Developmental language disorder (linguistic errors); LIHC cis rs6831256 0.550 rs9993109 chr4:3473659 A/G cg08741688 chr4:3415352 RGS12 -0.4 -5.86 -0.3 1.11e-8 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg04585227 chr7:158671570 WDR60 0.43 6.4 0.33 5.2e-10 Longevity; LIHC cis rs59698941 0.943 rs997633 chr5:132219304 A/T cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs9768139 0.708 rs921616 chr7:158117960 A/G cg06219351 chr7:158114137 PTPRN2 -0.21 -6.04 -0.31 3.96e-9 Calcium levels; LIHC cis rs1862618 0.671 rs28397234 chr5:56248428 T/G cg12311346 chr5:56204834 C5orf35 0.44 5.8 0.3 1.55e-8 Initial pursuit acceleration; LIHC cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg06212747 chr3:49208901 KLHDC8B 0.64 8.88 0.43 3.91e-17 Menarche (age at onset); LIHC cis rs7927592 0.913 rs11228276 chr11:68307525 A/G cg16797656 chr11:68205561 LRP5 0.51 8.01 0.4 1.84e-14 Total body bone mineral density; LIHC cis rs11098499 0.754 rs1511017 chr4:120250805 G/A cg09307838 chr4:120376055 NA 0.71 11.25 0.52 3.29e-25 Corneal astigmatism; LIHC cis rs317689 0.876 rs547332 chr12:69743639 C/G cg19645103 chr12:69753606 YEATS4 -0.44 -5.89 -0.3 9.4e-9 Response to diuretic therapy; LIHC cis rs10193935 0.792 rs13423729 chr2:42492874 C/T cg27598129 chr2:42591480 NA -0.67 -10.29 -0.49 8.21e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs11690935 1.000 rs6757773 chr2:172549630 T/A cg13550731 chr2:172543902 DYNC1I2 0.94 19.17 0.72 3.79e-56 Schizophrenia; LIHC cis rs4819052 0.851 rs10470246 chr21:46659017 C/G cg22633049 chr21:46681294 NA -0.37 -6.31 -0.32 8.65e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1005277 0.540 rs2224248 chr10:38451886 A/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs703842 0.616 rs870392 chr12:58219173 C/A cg18357645 chr12:58087776 OS9 -0.43 -6.13 -0.31 2.37e-9 Multiple sclerosis; LIHC trans rs916888 0.821 rs199504 chr17:44861003 C/T cg13957321 chr17:43675089 NA -0.49 -7.86 -0.39 4.98e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7312933 0.584 rs6582391 chr12:42634686 G/A cg01256987 chr12:42539512 GXYLT1 -0.41 -6.92 -0.35 2.2e-11 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs11711311 1.000 rs2603792 chr3:113509187 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.99 -0.35 1.45e-11 IgG glycosylation; LIHC cis rs921968 0.541 rs549026 chr2:219339283 T/C cg02176678 chr2:219576539 TTLL4 0.54 7.53 0.38 4.5e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 0.515 rs111560858 chr3:10166845 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.78 7.93 0.39 3.04e-14 Alzheimer's disease; LIHC cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg11494091 chr17:61959527 GH2 0.35 5.92 0.3 7.8e-9 Height; LIHC cis rs780096 0.546 rs7563162 chr2:27631191 C/T cg27432699 chr2:27873401 GPN1 -0.49 -7.12 -0.36 6.6e-12 Total body bone mineral density; LIHC cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs2858942 0.602 rs1211375 chr16:240280 G/T cg00126636 chr16:237282 NA 0.4 6.96 0.35 1.71e-11 Mean corpuscular hemoglobin; LIHC cis rs1555322 0.530 rs2425044 chr20:33869735 C/T cg08210727 chr20:33865349 NA 0.51 5.81 0.3 1.42e-8 Attention deficit hyperactivity disorder; LIHC cis rs11971779 0.680 rs6947215 chr7:139026638 A/G cg07862535 chr7:139043722 LUC7L2 0.53 9.48 0.46 4.45e-19 Diisocyanate-induced asthma; LIHC cis rs9916302 0.904 rs8079355 chr17:37473018 G/A cg00129232 chr17:37814104 STARD3 0.39 6.25 0.32 1.23e-9 Glomerular filtration rate (creatinine); LIHC cis rs727505 1.000 rs2402751 chr7:124434760 C/T cg23710748 chr7:124431027 NA -0.4 -6.98 -0.35 1.55e-11 Lewy body disease; LIHC cis rs1008375 1.000 rs62295634 chr4:17685346 C/A cg02297831 chr4:17616191 MED28 0.42 6.71 0.34 8.16e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs7412746 0.611 rs4970931 chr1:150910727 G/A cg17724175 chr1:150552817 MCL1 0.38 7.59 0.38 3.03e-13 Melanoma; LIHC cis rs5758511 0.680 rs5758662 chr22:42628088 T/C cg00645731 chr22:42541494 CYP2D7P1 0.53 8.47 0.42 7.16e-16 Birth weight; LIHC cis rs7552404 0.883 rs77773255 chr1:76217193 G/A cg22875332 chr1:76189707 ACADM 0.49 7.29 0.37 2.2e-12 Blood metabolite levels;Acylcarnitine levels; LIHC trans rs1728785 0.901 rs11075687 chr16:68655894 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.49 6.09 0.31 3.1e-9 Ulcerative colitis; LIHC cis rs2346177 0.542 rs13020043 chr2:46698431 A/T cg02822958 chr2:46747628 ATP6V1E2 0.51 7.56 0.38 3.86e-13 HDL cholesterol; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg07738955 chr17:38333606 RAPGEFL1 -0.4 -6.14 -0.32 2.3e-9 Calcium levels; LIHC cis rs9517313 0.523 rs4772104 chr13:99235677 G/A cg07423050 chr13:99094983 FARP1 -0.45 -7.54 -0.38 4.39e-13 Neuroticism; LIHC cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg27572855 chr1:25598939 RHD 0.41 8.91 0.43 3.19e-17 Erythrocyte sedimentation rate; LIHC cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg18252515 chr7:66147081 NA -1.29 -16.89 -0.67 5.55e-47 Diabetic kidney disease; LIHC cis rs903552 1.000 rs8027380 chr15:102005810 T/C cg25677261 chr15:102009856 PCSK6 -0.46 -6.24 -0.32 1.29e-9 Diabetic kidney disease; LIHC cis rs13064411 0.735 rs6438158 chr3:113217290 C/T cg18753928 chr3:113234510 CCDC52 -0.44 -6.27 -0.32 1.07e-9 Response to simvastatin treatment (PCSK9 protein level change); LIHC cis rs11792861 0.888 rs75543406 chr9:111816903 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.84 0.43 5.31e-17 Menarche (age at onset); LIHC cis rs9399137 0.507 rs56164974 chr6:135288716 C/T cg24558204 chr6:135376177 HBS1L 0.61 10.32 0.49 6.68e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs61677309 1.000 rs61706007 chr11:118167278 T/G cg06090739 chr11:118230722 UBE4A 0.35 6.37 0.33 6.26e-10 Lung cancer in ever smokers; LIHC cis rs1005277 0.579 rs1780116 chr10:38526621 C/T cg03665457 chr10:38645376 HSD17B7P2 -0.45 -6.54 -0.33 2.23e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2066819 1.000 rs79824801 chr12:56728137 T/C cg26734620 chr12:56694298 CS 1.26 11.0 0.51 2.78e-24 Psoriasis vulgaris; LIHC cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg20302342 chr1:156215951 PAQR6 0.32 6.2 0.32 1.65e-9 Tonsillectomy; LIHC cis rs12142240 0.698 rs56063031 chr1:46825433 C/T cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs7772486 0.754 rs6921073 chr6:146144377 G/A cg13319975 chr6:146136371 FBXO30 -0.35 -5.93 -0.31 7.4e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2439831 0.850 rs28684672 chr15:44107662 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.6 8.45 0.42 8.7e-16 Lung cancer in ever smokers; LIHC cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.72 10.65 0.5 4.61e-23 Lymphocyte counts; LIHC cis rs763121 0.813 rs4821807 chr22:39065582 A/G cg14440974 chr22:39074834 NA -0.42 -6.84 -0.35 3.56e-11 Menopause (age at onset); LIHC cis rs4713118 0.513 rs149972 chr6:27983227 C/T cg23485639 chr6:28045615 ZNF165 0.38 5.89 0.3 9.04e-9 Parkinson's disease; LIHC cis rs3806843 0.966 rs1030166 chr5:140185473 G/A cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.52e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs11252926 0.574 rs4881254 chr10:453567 C/T cg16346588 chr10:242978 ZMYND11 0.38 5.86 0.3 1.07e-8 Psychosis in Alzheimer's disease; LIHC cis rs801193 0.569 rs2013908 chr7:66121069 A/T cg11764359 chr7:65958608 NA -0.76 -13.01 -0.58 9.96e-32 Aortic root size; LIHC cis rs4654899 0.758 rs17453044 chr1:21517361 A/G cg08539965 chr1:21396338 EIF4G3 0.33 5.78 0.3 1.69e-8 Superior frontal gyrus grey matter volume; LIHC cis rs854572 0.600 rs705382 chr7:94955221 C/G cg20119798 chr7:94954144 PON1 -0.36 -6.08 -0.31 3.28e-9 Paraoxonase activity; LIHC cis rs9303401 0.659 rs36093395 chr17:56957357 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.34 0.58 5.91e-33 Cognitive test performance; LIHC cis rs6089829 0.962 rs6122352 chr20:61668284 T/C cg03213289 chr20:61660250 NA 0.51 8.99 0.44 1.73e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs11971779 0.715 rs6954219 chr7:139065110 G/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23187103 chr8:128748481 MYC 0.42 6.23 0.32 1.4e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs13191362 0.935 rs4273664 chr6:162955494 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.83 0.3 1.31e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg07590584 chr13:113140145 TUBGCP3 0.47 6.37 0.33 5.94e-10 Systolic blood pressure; LIHC cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg15691649 chr6:25882328 NA 0.52 6.49 0.33 2.97e-10 Intelligence (multi-trait analysis); LIHC cis rs7903847 0.701 rs11189173 chr10:99138792 T/C cg06359132 chr10:99160096 RRP12 -0.4 -5.91 -0.3 8.13e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs35306767 0.903 rs17159950 chr10:875287 T/G cg26597838 chr10:835615 NA 1.2 13.91 0.6 3.69e-35 Eosinophil percentage of granulocytes; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg04054907 chr8:17104065 CNOT7;VPS37A 0.45 6.05 0.31 3.9e-9 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs6840360 1.000 rs6849050 chr4:152599902 C/T cg22705602 chr4:152727874 NA -0.31 -6.56 -0.33 2.03e-10 Intelligence (multi-trait analysis); LIHC cis rs12497850 0.931 rs13315711 chr3:48986399 A/T cg07636037 chr3:49044803 WDR6 0.92 16.54 0.67 1.44e-45 Parkinson's disease; LIHC cis rs1190552 0.639 rs3742446 chr14:102975572 C/T cg10241871 chr14:102965420 TECPR2 -0.47 -6.91 -0.35 2.38e-11 Blood protein levels; LIHC cis rs4908768 0.906 rs78110809 chr1:8573008 C/T cg20416874 chr1:8611966 RERE 0.59 9.07 0.44 9.77e-18 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs57590327 0.503 rs12152272 chr3:81911684 G/A cg07356753 chr3:81810745 GBE1 -0.5 -7.69 -0.38 1.54e-13 Extraversion; LIHC cis rs4930103 0.591 rs11042048 chr11:1986240 C/G cg23202291 chr11:1979235 NA 0.49 7.32 0.37 1.74e-12 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs1555322 0.530 rs6060347 chr20:33874151 A/G cg07134254 chr20:33865797 NA 0.5 5.97 0.31 5.9e-9 Attention deficit hyperactivity disorder; LIHC cis rs763121 0.925 rs5757165 chr22:38994577 C/T cg06022373 chr22:39101656 GTPBP1 0.72 14.4 0.61 4.38e-37 Menopause (age at onset); LIHC cis rs1801251 1.000 rs36007169 chr2:233621834 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.5 0.53 4.14e-26 Coronary artery disease; LIHC cis rs804292 1.000 rs804292 chr8:11643915 C/T cg26752888 chr8:11627280 NEIL2 -0.87 -8.95 -0.44 2.24e-17 Alcohol dependence;Nicotine use; LIHC cis rs7224314 1.000 rs62084082 chr17:65388046 A/G cg01507342 chr17:65387096 PITPNC1 -0.46 -5.9 -0.3 8.64e-9 Diisocyanate-induced asthma; LIHC cis rs2070488 0.775 rs6599211 chr3:38558830 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.69 -11.36 -0.52 1.42e-25 Electrocardiographic conduction measures; LIHC cis rs116248771 0.793 rs6765967 chr3:158347310 T/C cg16708174 chr3:158430962 RARRES1 0.48 6.45 0.33 3.77e-10 diarrhoeal disease at age 2; LIHC cis rs9467773 1.000 rs1321479 chr6:26501897 C/T cg09904177 chr6:26538194 HMGN4 -0.64 -13.57 -0.59 7.22e-34 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs780112 chr2:27665361 C/G cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC cis rs3960554 1.000 rs2097947 chr7:75836382 A/T cg16684958 chr7:75615977 POR 0.39 5.9 0.3 8.65e-9 Eotaxin levels; LIHC cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg09913183 chr17:42254507 C17orf65;ASB16 0.69 10.84 0.51 9.52e-24 Total body bone mineral density; LIHC trans rs9929218 0.954 rs9929239 chr16:68821126 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.44 -0.42 9.07e-16 Colorectal cancer; LIHC cis rs1552244 0.543 rs28719585 chr3:10050813 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.75 0.39 1.05e-13 Alzheimer's disease; LIHC cis rs796364 0.806 rs1605900 chr2:200870197 C/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.67 7.41 0.37 1.02e-12 Schizophrenia; LIHC cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg11494091 chr17:61959527 GH2 0.36 6.09 0.31 2.96e-9 Height; LIHC cis rs6456156 0.524 rs6932740 chr6:167466439 G/A cg07741184 chr6:167504864 NA 0.29 7.05 0.36 1.02e-11 Primary biliary cholangitis; LIHC cis rs2731664 0.792 rs335467 chr5:176890642 A/G cg23176889 chr5:176863531 GRK6 -0.7 -12.19 -0.55 1.24e-28 Intelligence (multi-trait analysis); LIHC cis rs295140 0.605 rs159320 chr2:201187775 A/G cg23649088 chr2:200775458 C2orf69 0.43 5.99 0.31 5.25e-9 QT interval; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg26157802 chr2:220042863 FAM134A;C2orf24 -0.51 -6.07 -0.31 3.4e-9 Systolic blood pressure; LIHC cis rs6912958 0.535 rs242283 chr6:88030931 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.36 6.97 0.35 1.62e-11 Monocyte percentage of white cells; LIHC cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg07677032 chr17:61819896 STRADA 0.43 6.23 0.32 1.4e-9 Prudent dietary pattern; LIHC cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.96 -12.57 -0.56 4.75e-30 Alzheimer's disease; LIHC cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg27572855 chr1:25598939 RHD -0.38 -8.13 -0.4 7.79e-15 Erythrocyte sedimentation rate; LIHC cis rs10857712 0.687 rs11101742 chr10:135224372 C/G cg15472797 chr10:135243109 NA -0.36 -5.93 -0.31 7.45e-9 Systemic lupus erythematosus; LIHC cis rs3768617 0.510 rs7518957 chr1:183093028 A/T ch.1.3577855R chr1:183094577 LAMC1 -0.6 -10.72 -0.5 2.53e-23 Fuchs's corneal dystrophy; LIHC cis rs12744310 0.887 rs35021924 chr1:41786907 A/G cg03962019 chr1:41807865 NA 0.38 6.11 0.31 2.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs12744310 0.887 rs12028244 chr1:41809162 C/T cg03387723 chr1:41708464 SCMH1 -0.33 -5.89 -0.3 9.22e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs35110281 0.548 rs7276316 chr21:45029333 A/T cg21573476 chr21:45109991 RRP1B -0.56 -10.65 -0.5 4.72e-23 Mean corpuscular volume; LIHC cis rs10504073 0.647 rs4873317 chr8:50021111 C/T cg00325661 chr8:49890786 NA 0.32 7.27 0.37 2.45e-12 Blood metabolite ratios; LIHC cis rs748404 0.697 rs493444 chr15:43566470 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.43 6.55 0.33 2.07e-10 Lung cancer; LIHC cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg25072359 chr17:41440525 NA 0.38 6.06 0.31 3.67e-9 Menopause (age at onset); LIHC cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.37 0.45 1e-18 Bipolar disorder; LIHC cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg09222892 chr1:25734099 RHCE -0.45 -8.28 -0.41 2.86e-15 Erythrocyte sedimentation rate; LIHC cis rs17685 0.753 rs1806885 chr7:75785612 T/G cg01364799 chr7:75623366 TMEM120A -0.51 -7.63 -0.38 2.38e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9733 0.596 rs34600506 chr1:150687808 C/G cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs34779708 0.931 rs4934702 chr10:35323074 T/C cg03585969 chr10:35415529 CREM 0.77 11.55 0.53 2.86e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg14893161 chr1:205819251 PM20D1 0.68 9.83 0.47 3.12e-20 Menarche (age at onset); LIHC cis rs1267303 0.600 rs57100184 chr1:47004710 A/C cg25110126 chr1:46999211 NA 0.51 6.95 0.35 1.81e-11 Monobrow; LIHC cis rs7633857 0.512 rs1868109 chr3:160682500 G/A cg03342759 chr3:160939853 NMD3 -0.45 -6.35 -0.32 6.72e-10 Educational attainment (years of education); LIHC cis rs11166927 1.000 rs12549587 chr8:140804310 G/A cg16909799 chr8:140841666 TRAPPC9 0.51 8.0 0.4 1.92e-14 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs1799949 0.965 rs8176310 chr17:41199913 T/C cg23758822 chr17:41437982 NA 0.95 17.52 0.69 1.67e-49 Menopause (age at onset); LIHC cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg17971929 chr21:40555470 PSMG1 0.82 9.9 0.47 1.76e-20 Cognitive function; LIHC cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg18230493 chr5:56204884 C5orf35 -0.45 -6.27 -0.32 1.11e-9 Initial pursuit acceleration; LIHC cis rs644799 1.000 rs651445 chr11:95539122 T/A cg25478527 chr11:95522999 CEP57;FAM76B 0.42 5.8 0.3 1.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7917772 0.502 rs4919670 chr10:104515799 C/A cg22532475 chr10:104410764 TRIM8 0.36 6.25 0.32 1.19e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs400736 1.000 rs400736 chr1:8078309 T/C cg25007680 chr1:8021821 PARK7 0.58 9.33 0.45 1.4e-18 Response to antidepressants and depression; LIHC cis rs208520 0.837 rs208467 chr6:66914837 T/C cg07460842 chr6:66804631 NA -0.69 -7.71 -0.38 1.37e-13 Exhaled nitric oxide output; LIHC cis rs2839186 0.934 rs17182538 chr21:47705673 C/A cg05896524 chr21:47604654 C21orf56 0.45 6.73 0.34 7.03e-11 Testicular germ cell tumor; LIHC cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg25894440 chr7:65020034 NA -0.54 -6.22 -0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs9640161 0.673 rs34489187 chr7:150044379 G/A cg17279839 chr7:150038598 RARRES2 0.59 12.02 0.54 5.34e-28 Blood protein levels;Circulating chemerin levels; LIHC cis rs748404 0.660 rs548704 chr15:43791706 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.46 7.91 0.39 3.53e-14 Lung cancer; LIHC cis rs748404 0.697 rs493177 chr15:43543258 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.43 0.41 9.56e-16 Lung cancer; LIHC cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg21724239 chr8:58056113 NA 0.59 7.32 0.37 1.83e-12 Developmental language disorder (linguistic errors); LIHC cis rs2075371 0.966 rs1619682 chr7:133996703 T/G cg20476274 chr7:133979776 SLC35B4 0.74 12.13 0.55 2.1e-28 Mean platelet volume; LIHC cis rs644799 1.000 rs580255 chr11:95577929 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.67 9.61 0.46 1.6e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs1385374 0.858 rs11059927 chr12:129294333 T/C cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.75 0.39 1.09e-13 Systemic lupus erythematosus; LIHC cis rs11690935 0.610 rs3770458 chr2:172651287 C/T cg13550731 chr2:172543902 DYNC1I2 0.62 11.18 0.52 6.28e-25 Schizophrenia; LIHC cis rs7605378 0.567 rs717915 chr2:200714766 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 0.57 7.44 0.37 8.41e-13 Osteoporosis; LIHC cis rs600806 0.815 rs10745356 chr1:109960270 C/A cg23091122 chr1:110024289 SYPL2 -0.46 -6.09 -0.31 2.96e-9 Intelligence (multi-trait analysis); LIHC cis rs9814567 1.000 rs6439484 chr3:134249899 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4665809 0.877 rs34536218 chr2:26287376 T/A cg26119090 chr2:26468346 HADHA;HADHB 0.72 7.87 0.39 4.68e-14 Gut microbiome composition (summer); LIHC cis rs7238033 0.663 rs7234986 chr18:43320604 A/G cg20610511 chr18:43302872 SLC14A1 0.39 6.52 0.33 2.55e-10 Bladder cancer; LIHC cis rs11758351 0.866 rs77889957 chr6:26207435 A/G cg03785755 chr6:26196794 NA 0.5 5.88 0.3 9.89e-9 Gout;Renal underexcretion gout; LIHC cis rs7412746 0.611 rs2228099 chr1:150808889 C/G cg17724175 chr1:150552817 MCL1 0.38 7.72 0.39 1.31e-13 Melanoma; LIHC cis rs67311347 0.577 rs1317217 chr3:40271697 T/G cg13409248 chr3:40428643 ENTPD3 0.41 6.6 0.34 1.53e-10 Renal cell carcinoma; LIHC cis rs34779708 0.931 rs11597392 chr10:35288575 T/C cg03585969 chr10:35415529 CREM 0.85 12.77 0.57 8.03e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2204008 0.693 rs12372025 chr12:38202028 G/A cg26384229 chr12:38710491 ALG10B 0.85 10.49 0.49 1.73e-22 Bladder cancer; LIHC cis rs1865760 1.000 rs3830057 chr6:25918510 G/T cg03517284 chr6:25882590 NA -0.38 -5.76 -0.3 1.83e-8 Height; LIHC cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg11502198 chr6:26597334 ABT1 0.64 9.97 0.47 9.9e-21 Intelligence (multi-trait analysis); LIHC cis rs370915 0.542 rs13124558 chr4:187794175 T/C cg12892747 chr4:187813459 NA -0.37 -5.74 -0.3 2.07e-8 Gout; LIHC cis rs72781680 0.652 rs72794281 chr2:23893265 G/A cg08917208 chr2:24149416 ATAD2B 1.02 8.29 0.41 2.55e-15 Lymphocyte counts; LIHC cis rs6546550 0.867 rs4852349 chr2:70076954 A/T cg02498382 chr2:70120550 SNRNP27 -0.39 -6.53 -0.33 2.44e-10 Prevalent atrial fibrillation; LIHC cis rs870825 0.616 rs6833858 chr4:185639961 C/T cg04058563 chr4:185651563 MLF1IP 0.67 7.0 0.35 1.34e-11 Blood protein levels; LIHC cis rs35110281 0.616 rs2236666 chr21:45109856 T/C cg21573476 chr21:45109991 RRP1B -0.63 -11.88 -0.54 1.69e-27 Mean corpuscular volume; LIHC cis rs6430585 0.528 rs309167 chr2:136669264 C/T cg25344623 chr2:136566232 LCT -0.38 -6.1 -0.31 2.88e-9 Corneal structure; LIHC cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.6 -0.34 1.53e-10 Bipolar disorder and schizophrenia; LIHC cis rs12134245 0.747 rs35654098 chr1:92001452 T/A cg07090678 chr1:91966139 CDC7 0.51 7.0 0.35 1.37e-11 Breast cancer; LIHC cis rs7633770 0.786 rs950190 chr3:46683377 C/T cg11219411 chr3:46661640 NA 0.45 8.08 0.4 1.12e-14 Coronary artery disease; LIHC cis rs7412746 0.658 rs12097963 chr1:150870450 T/C cg15448220 chr1:150897856 SETDB1 0.44 6.97 0.35 1.64e-11 Melanoma; LIHC cis rs2180341 0.960 rs6900074 chr6:127685893 A/G cg27446573 chr6:127587934 RNF146 1.08 16.9 0.67 5.37e-47 Breast cancer; LIHC cis rs644799 0.509 rs580181 chr11:95643040 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.57 8.04 0.4 1.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg10824722 chr1:206506826 NA 0.41 6.3 0.32 9.03e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9473924 0.505 rs2223869 chr6:50904239 C/T cg14470998 chr6:50812995 TFAP2B 0.94 10.92 0.51 5.15e-24 Body mass index; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg27029403 chr14:104029012 BAG5;C14orf153 -0.43 -6.08 -0.31 3.16e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs589448 0.538 rs683790 chr12:69751434 T/G cg22834771 chr12:69754056 YEATS4 -0.45 -7.46 -0.37 7.38e-13 Cerebrospinal fluid biomarker levels; LIHC cis rs1355223 0.583 rs2116085 chr11:34884001 C/A cg06937548 chr11:34938143 PDHX;APIP 0.41 5.83 0.3 1.27e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7927771 0.826 rs7925389 chr11:47466790 A/T cg20307385 chr11:47447363 PSMC3 -0.49 -6.32 -0.32 8.38e-10 Subjective well-being; LIHC cis rs600806 0.850 rs2140924 chr1:109935775 A/C cg23091122 chr1:110024289 SYPL2 -0.45 -5.99 -0.31 5.28e-9 Intelligence (multi-trait analysis); LIHC cis rs7129220 0.588 rs60257382 chr11:10122172 C/T cg01453529 chr11:10209919 SBF2 -0.39 -6.9 -0.35 2.47e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; LIHC cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg23205692 chr1:25664452 TMEM50A 0.39 6.21 0.32 1.54e-9 Erythrocyte sedimentation rate; LIHC cis rs4474465 0.646 rs10751297 chr11:78278567 C/T cg27205649 chr11:78285834 NARS2 0.5 7.87 0.39 4.82e-14 Alzheimer's disease (survival time); LIHC cis rs12594515 1.000 rs8027000 chr15:45987795 T/C cg19682013 chr15:45996608 NA 0.41 7.17 0.36 4.71e-12 Waist circumference;Weight; LIHC cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg25204440 chr1:209979598 IRF6 0.53 8.07 0.4 1.24e-14 Cleft lip with or without cleft palate; LIHC cis rs3761847 0.622 rs4837807 chr9:123792005 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 5.74 0.3 2.12e-8 Rheumatoid arthritis; LIHC trans rs13113518 0.812 rs13125984 chr4:56321269 G/A cg15358633 chr12:38710606 ALG10B 0.44 6.29 0.32 9.77e-10 Height; LIHC cis rs2749592 0.531 rs10764134 chr10:37856660 T/C cg00409905 chr10:38381863 ZNF37A 0.51 8.55 0.42 4.2e-16 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6088580 0.601 rs6120668 chr20:33099793 A/G cg08999081 chr20:33150536 PIGU 0.67 13.46 0.59 1.89e-33 Glomerular filtration rate (creatinine); LIHC cis rs58688157 0.960 rs1055382 chr11:612182 T/C cg01842473 chr11:617407 IRF7;MUPCDH -0.57 -6.31 -0.32 8.65e-10 Systemic lupus erythematosus; LIHC cis rs7618501 0.633 rs4688690 chr3:50022292 G/A cg24110177 chr3:50126178 RBM5 -0.48 -7.66 -0.38 1.89e-13 Intelligence (multi-trait analysis); LIHC cis rs17685 0.753 rs1637045 chr7:75703895 T/C cg04592579 chr7:75616294 TMEM120A 0.39 6.75 0.34 6.41e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs57244997 0.725 rs73028490 chr6:162421657 T/C cg17173639 chr6:162384350 PARK2 -0.57 -7.23 -0.36 3.11e-12 Mosquito bite size; LIHC cis rs3008870 0.755 rs3736905 chr1:67392614 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.63 10.69 0.5 3.44e-23 Lymphocyte percentage of white cells; LIHC cis rs7727544 0.735 rs272894 chr5:131662460 C/T cg24060327 chr5:131705240 SLC22A5 -0.59 -8.55 -0.42 4.31e-16 Blood metabolite levels; LIHC cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg24531977 chr5:56204891 C5orf35 -0.67 -9.57 -0.46 2.3e-19 Initial pursuit acceleration; LIHC cis rs748404 0.660 rs2439845 chr15:43722610 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 7.14 0.36 5.5e-12 Lung cancer; LIHC trans rs526821 0.553 rs510095 chr11:55289154 T/C cg15704280 chr7:45808275 SEPT13 -0.52 -7.98 -0.4 2.2e-14 Pediatric bone mineral density (spine); LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg02592271 chr2:27665507 KRTCAP3 -0.46 -6.43 -0.33 4.37e-10 Total body bone mineral density; LIHC cis rs17253792 0.915 rs75296402 chr14:56182491 C/T cg01858014 chr14:56050164 KTN1 -0.75 -7.41 -0.37 1e-12 Putamen volume; LIHC cis rs35883536 1.000 rs35883536 chr1:101106534 G/A cg14515779 chr1:101123966 NA -0.67 -13.22 -0.58 1.65e-32 Monocyte count; LIHC cis rs72781680 0.752 rs55806536 chr2:23912697 A/G cg08917208 chr2:24149416 ATAD2B 0.96 7.94 0.39 2.89e-14 Lymphocyte counts; LIHC cis rs9430161 0.579 rs7542158 chr1:11040193 G/A cg27631724 chr1:11040367 C1orf127 0.38 7.75 0.39 1.05e-13 Ewing sarcoma; LIHC cis rs9309473 0.653 rs6718843 chr2:73852505 C/A cg20560298 chr2:73613845 ALMS1 -0.53 -6.65 -0.34 1.13e-10 Metabolite levels; LIHC trans rs1728785 1.000 rs1182968 chr16:68573945 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.5 6.18 0.32 1.78e-9 Ulcerative colitis; LIHC trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg11235426 chr6:292522 DUSP22 -0.51 -7.01 -0.35 1.24e-11 Menopause (age at onset); LIHC cis rs6456156 0.565 rs2181058 chr6:167465330 A/T cg07741184 chr6:167504864 NA 0.29 7.05 0.36 1.02e-11 Primary biliary cholangitis; LIHC cis rs9311474 0.581 rs13621 chr3:52558133 T/C cg18404041 chr3:52824283 ITIH1 -0.45 -7.09 -0.36 7.53e-12 Electroencephalogram traits; LIHC cis rs116095464 0.558 rs113796397 chr5:246503 A/G cg22496380 chr5:211416 CCDC127 -1.02 -10.62 -0.5 6e-23 Breast cancer; LIHC cis rs9309473 0.898 rs7580750 chr2:73788126 A/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.77 -0.34 5.56e-11 Metabolite levels; LIHC cis rs3888647 0.561 rs4758617 chr11:2995185 T/A cg20651018 chr11:3035856 CARS -0.35 -5.98 -0.31 5.6e-9 Type 2 diabetes; LIHC cis rs644148 0.836 rs2571111 chr19:45000581 C/A cg15540054 chr19:45004280 ZNF180 -0.79 -11.76 -0.54 4.82e-27 Personality dimensions; LIHC cis rs1003719 0.646 rs2835672 chr21:38581234 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.23 -0.48 1.3e-21 Eye color traits; LIHC cis rs7044106 0.762 rs966396 chr9:123453281 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 11.19 0.52 5.62e-25 Hip circumference adjusted for BMI; LIHC cis rs9929218 0.954 rs9646284 chr16:68791306 C/G cg01231543 chr16:68741748 NA 0.36 5.8 0.3 1.49e-8 Colorectal cancer; LIHC cis rs7607369 0.648 rs17470271 chr2:219651995 A/T cg02985541 chr2:219472218 PLCD4 0.37 5.95 0.31 6.55e-9 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg20887711 chr4:1340912 KIAA1530 -0.49 -7.44 -0.37 8.28e-13 Obesity-related traits; LIHC cis rs892961 0.932 rs55661113 chr17:75408386 A/C cg01320579 chr17:75405842 SEPT9 0.54 7.21 0.36 3.6e-12 Airflow obstruction; LIHC cis rs7772486 0.654 rs6906402 chr6:146089307 C/G cg23711669 chr6:146136114 FBXO30 -0.75 -13.37 -0.59 4.42e-33 Lobe attachment (rater-scored or self-reported); LIHC cis rs6539267 0.741 rs35816179 chr12:106693710 T/C cg00173435 chr12:106696525 TCP11L2 0.6 8.12 0.4 8.33e-15 Tourette syndrome; LIHC cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg12419862 chr22:24373484 LOC391322 -0.58 -7.92 -0.39 3.37e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7659604 1.000 rs10016433 chr4:122664771 A/G cg19748678 chr4:122722346 EXOSC9 0.35 5.86 0.3 1.06e-8 Type 2 diabetes; LIHC cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.68 0.8 5.83e-78 Prudent dietary pattern; LIHC cis rs7208859 0.725 rs6505215 chr17:29189903 C/A cg13385521 chr17:29058706 SUZ12P 0.75 7.63 0.38 2.35e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg22903471 chr2:27725779 GCKR -0.51 -9.02 -0.44 1.4e-17 Total body bone mineral density; LIHC cis rs16854884 0.657 rs62268458 chr3:143736219 T/C cg06585982 chr3:143692056 C3orf58 0.48 5.98 0.31 5.47e-9 Economic and political preferences (feminism/equality); LIHC cis rs7534824 0.625 rs17610202 chr1:101429724 C/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 7.17 0.36 4.56e-12 Refractive astigmatism; LIHC cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg03735888 chr19:58951602 ZNF132 -0.4 -7.15 -0.36 5.2e-12 Uric acid clearance; LIHC cis rs7119038 0.865 rs7117261 chr11:118741157 T/C cg19308663 chr11:118741387 NA -0.47 -6.07 -0.31 3.45e-9 Sjögren's syndrome; LIHC cis rs9549367 0.789 rs2302754 chr13:113898385 C/T cg00898013 chr13:113819073 PROZ 0.4 6.93 0.35 2.14e-11 Platelet distribution width; LIHC cis rs12928939 1.000 rs12928939 chr16:71800045 G/A cg03805757 chr16:71968109 PKD1L3 -0.72 -8.33 -0.41 1.95e-15 Post bronchodilator FEV1; LIHC cis rs796364 0.806 rs203766 chr2:200902672 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -7.23 -0.36 3.27e-12 Schizophrenia; LIHC cis rs2228479 0.702 rs11646374 chr16:89857935 G/A cg00800038 chr16:89945340 TCF25 -0.61 -8.68 -0.42 1.69e-16 Skin colour saturation; LIHC cis rs67460515 0.892 rs2054710 chr3:161090616 C/T cg03342759 chr3:160939853 NMD3 -0.55 -8.18 -0.4 5.66e-15 Parkinson's disease; LIHC cis rs34540877 0.793 rs12979236 chr19:33142895 G/C cg22980127 chr19:33182716 NUDT19 0.89 6.22 0.32 1.43e-9 Red cell distribution width; LIHC cis rs1008375 1.000 rs12648232 chr4:17612537 C/T cg02297831 chr4:17616191 MED28 -0.46 -6.86 -0.35 3.31e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs422249 0.512 rs174554 chr11:61579463 A/G cg27386326 chr11:61587980 NA 0.7 14.85 0.63 7.91e-39 Trans fatty acid levels; LIHC cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.53 -7.87 -0.39 4.8e-14 Age at first birth; LIHC cis rs2997447 0.846 rs7520344 chr1:26397286 C/T cg19633962 chr1:26362018 EXTL1 -0.68 -6.51 -0.33 2.74e-10 QRS complex (12-leadsum); LIHC trans rs9929218 0.953 rs28608872 chr16:68802038 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.78 -0.43 8.25e-17 Colorectal cancer; LIHC cis rs12477438 0.798 rs13414153 chr2:99624748 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.58 -0.38 3.34e-13 Chronic sinus infection; LIHC cis rs7772486 0.597 rs2246132 chr6:146182515 C/G cg23711669 chr6:146136114 FBXO30 0.64 10.01 0.48 7.28e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg15320075 chr8:145703422 NA -0.55 -9.46 -0.46 5.3e-19 Age at first birth; LIHC cis rs4450131 0.522 rs876352 chr10:126337350 C/T cg20435097 chr10:126320824 FAM53B 0.69 12.55 0.56 5.58e-30 White blood cell count (basophil); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg03710481 chr6:122931605 PKIB 0.44 6.59 0.34 1.66e-10 Calcium levels; LIHC cis rs2708977 0.666 rs17685664 chr2:97315570 C/T cg01950434 chr2:97203154 ARID5A 0.51 7.34 0.37 1.62e-12 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs4466137 1.000 rs4466137 chr5:82985739 A/C cg16102102 chr5:83017553 HAPLN1 -0.56 -8.44 -0.42 8.81e-16 Prostate cancer; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs8180040 0.653 rs6808742 chr3:47051512 G/A cg16586182 chr3:47516702 SCAP -0.5 -9.09 -0.44 8.32e-18 Colorectal cancer; LIHC cis rs918629 0.798 rs6894651 chr5:95292267 C/T cg10483112 chr5:95245456 ELL2 -0.35 -6.05 -0.31 3.91e-9 IgG glycosylation; LIHC cis rs155076 1.000 rs261406 chr13:21855854 G/A cg11317459 chr13:21872234 NA -1.16 -13.64 -0.59 4.12e-34 White matter hyperintensity burden; LIHC cis rs1577917 0.958 rs3900313 chr6:86537154 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs611744 0.967 rs652485 chr8:109202696 G/A cg21045802 chr8:109455806 TTC35 0.5 8.62 0.42 2.58e-16 Dupuytren's disease; LIHC cis rs10461617 0.592 rs6450403 chr5:56062737 A/C cg24531977 chr5:56204891 C5orf35 -0.6 -9.04 -0.44 1.22e-17 Type 2 diabetes; LIHC cis rs1707322 0.717 rs2275086 chr1:46085879 C/G cg03146154 chr1:46216737 IPP -0.56 -9.35 -0.45 1.16e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs708547 0.647 rs781666 chr4:57830981 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.47 7.03 0.36 1.11e-11 Response to bleomycin (chromatid breaks); LIHC cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.99 9.3 0.45 1.65e-18 Platelet count; LIHC cis rs10779751 0.881 rs2744815 chr1:11360957 C/T cg08854313 chr1:11322531 MTOR 0.75 12.59 0.56 4.02e-30 Body mass index; LIHC cis rs2380220 0.808 rs2716070 chr6:95912375 T/C cg04719120 chr6:96025338 MANEA -0.56 -6.0 -0.31 4.98e-9 Behavioural disinhibition (generation interaction); LIHC cis rs546131 0.642 rs566798 chr11:34852277 A/G cg11058730 chr11:34937778 PDHX;APIP -0.62 -8.96 -0.44 2.11e-17 Lung disease severity in cystic fibrosis; LIHC cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs2224539 0.605 rs2103946 chr20:38465349 C/G cg21682942 chr2:85824657 RNF181 0.36 6.13 0.31 2.43e-9 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs875971 0.660 rs10272357 chr7:66063074 G/A cg14393609 chr7:65229607 NA -0.38 -5.98 -0.31 5.66e-9 Aortic root size; LIHC cis rs10751667 0.600 rs10794342 chr11:924904 C/T cg11406765 chr11:980039 AP2A2 -0.34 -5.71 -0.3 2.46e-8 Alzheimer's disease (late onset); LIHC cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg14393609 chr7:65229607 NA 0.44 6.56 0.33 2.05e-10 Calcium levels; LIHC cis rs2637266 0.902 rs2583056 chr10:78399498 A/G cg18941641 chr10:78392320 NA 0.29 6.34 0.32 7.39e-10 Pulmonary function; LIHC cis rs4727027 0.834 rs7811446 chr7:148773226 G/T cg23583168 chr7:148888333 NA -0.66 -9.33 -0.45 1.36e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs2304069 0.954 rs2340462 chr5:149415219 G/A cg22760475 chr5:149380129 HMGXB3;TIGD6 0.89 11.34 0.52 1.62e-25 HIV-1 control; LIHC cis rs4660306 0.677 rs11211110 chr1:45904815 C/T cg03123370 chr1:45965343 CCDC163P;MMACHC -0.63 -6.49 -0.33 3.02e-10 Homocysteine levels; LIHC cis rs637571 0.522 rs493899 chr11:65747952 A/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.28 0.45 1.98e-18 Eosinophil percentage of white cells; LIHC cis rs4378999 0.660 rs6800279 chr3:51086691 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.39 -5.79 -0.3 1.59e-8 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs8017423 0.935 rs10147186 chr14:90779879 G/C cg04374321 chr14:90722782 PSMC1 0.71 13.21 0.58 1.71e-32 Mortality in heart failure; LIHC cis rs10861342 1.000 rs12320123 chr12:105492167 C/T cg23923672 chr12:105501055 KIAA1033 0.69 8.44 0.42 9.36e-16 IgG glycosylation; LIHC cis rs8062405 1.000 rs62036626 chr16:28844284 A/G cg00204512 chr16:28754710 NA 0.34 6.35 0.32 7.04e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs17376456 0.825 rs67328989 chr5:93243133 T/A cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs12477438 0.765 rs7591794 chr2:99567514 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.41 -0.37 1.01e-12 Chronic sinus infection; LIHC cis rs10256972 0.521 rs7811577 chr7:1102829 C/G cg23978390 chr7:1156363 C7orf50 0.41 5.79 0.3 1.58e-8 Longevity;Endometriosis; LIHC cis rs6546550 0.867 rs1551374 chr2:70079633 C/T cg02498382 chr2:70120550 SNRNP27 -0.37 -6.16 -0.32 2.06e-9 Prevalent atrial fibrillation; LIHC cis rs7945705 0.712 rs61876274 chr11:9019190 A/T cg12365402 chr11:9010492 NRIP3 0.35 9.09 0.44 7.99e-18 Hemoglobin concentration; LIHC cis rs2625529 0.775 rs4777484 chr15:72376543 T/C cg16672083 chr15:72433130 SENP8 -0.31 -5.82 -0.3 1.37e-8 Red blood cell count; LIHC cis rs6120849 0.586 rs2025096 chr20:33540000 G/A cg06115741 chr20:33292138 TP53INP2 0.49 5.92 0.3 7.78e-9 Protein C levels; LIHC cis rs67311347 0.635 rs73071706 chr3:40288190 C/A cg10755058 chr3:40428713 ENTPD3 0.37 6.06 0.31 3.63e-9 Renal cell carcinoma; LIHC cis rs72627509 0.857 rs55762216 chr4:57765731 G/C cg26694713 chr4:57773883 REST 0.74 10.31 0.49 6.87e-22 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs951366 0.617 rs823080 chr1:205789282 G/A cg26354017 chr1:205819088 PM20D1 0.86 12.9 0.57 2.59e-31 Menarche (age at onset); LIHC cis rs11577318 0.626 rs11806568 chr1:26686837 C/A cg18121669 chr1:26560928 CCDC21 -0.49 -7.37 -0.37 1.27e-12 Granulocyte percentage of myeloid white cells; LIHC cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg00656387 chr3:40428638 ENTPD3 0.49 8.35 0.41 1.73e-15 Renal cell carcinoma; LIHC cis rs34172651 0.517 rs200528 chr16:24759131 A/G cg00339695 chr16:24857497 SLC5A11 -0.73 -11.04 -0.51 1.95e-24 Intelligence (multi-trait analysis); LIHC cis rs17253792 0.822 rs10150498 chr14:56064124 G/T cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC trans rs12614435 0.512 rs16866420 chr2:179491235 A/C cg14011486 chr1:26737247 LIN28 0.46 6.83 0.35 3.79e-11 Atrial fibrillation; LIHC cis rs67311347 0.869 rs6790495 chr3:40366770 C/T cg00656387 chr3:40428638 ENTPD3 0.43 6.96 0.35 1.75e-11 Renal cell carcinoma; LIHC trans rs17685 0.884 rs6978677 chr7:75636240 C/T cg19862616 chr7:65841803 NCRNA00174 0.71 12.58 0.56 4.4e-30 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1816752 0.905 rs2000153 chr13:24979890 G/A cg02811702 chr13:24901961 NA 0.26 6.04 0.31 3.98e-9 Obesity-related traits; LIHC cis rs950776 0.714 rs472054 chr15:78887994 A/G cg06917634 chr15:78832804 PSMA4 -0.59 -8.01 -0.4 1.77e-14 Sudden cardiac arrest; LIHC cis rs2153535 0.541 rs1414353 chr6:8485642 C/G cg07606381 chr6:8435919 SLC35B3 0.79 11.87 0.54 1.95e-27 Motion sickness; LIHC cis rs17021463 0.902 rs2016483 chr4:95229039 A/T cg11021082 chr4:95130006 SMARCAD1 -0.47 -8.66 -0.42 1.91e-16 Testicular germ cell tumor; LIHC trans rs17685 0.753 rs2302435 chr7:75676987 G/A cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.32 -0.7 1.01e-52 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10193935 0.901 rs997288 chr2:42525582 C/G cg27598129 chr2:42591480 NA -0.67 -10.41 -0.49 3.2800000000000002e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs10791323 0.572 rs1114367 chr11:133737304 G/T cg06766960 chr11:133703094 NA -0.45 -6.89 -0.35 2.67e-11 Childhood ear infection; LIHC cis rs1790761 0.692 rs614080 chr11:67347287 G/A cg00290607 chr11:67383545 NA 0.38 5.83 0.3 1.3e-8 Mean corpuscular volume; LIHC cis rs600806 0.813 rs4970760 chr1:109985439 A/G cg16275483 chr1:110013120 SYPL2 -0.48 -6.03 -0.31 4.33e-9 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.514 rs4980444 chr11:49550764 T/A cg15704280 chr7:45808275 SEPT13 -0.98 -20.13 -0.74 5.24e-60 Coronary artery disease; LIHC cis rs11711311 0.824 rs9833810 chr3:113363762 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.36 -5.9 -0.3 8.51e-9 IgG glycosylation; LIHC cis rs2120019 1.000 rs12324912 chr15:75361006 G/A cg11632617 chr15:75315747 PPCDC -0.45 -6.37 -0.33 6.25e-10 Blood trace element (Zn levels); LIHC cis rs807029 0.577 rs3740490 chr10:102756743 G/C cg17130504 chr10:102756923 LZTS2 0.55 7.56 0.38 3.84e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC trans rs2739330 0.760 rs5751761 chr22:24243736 A/G cg06437703 chr8:37914619 EIF4EBP1 0.57 8.33 0.41 1.92e-15 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.2 0.45 3.52e-18 Bipolar disorder; LIHC trans rs8113308 0.810 rs11880193 chr19:52448669 G/C cg14959425 chr7:20447707 ITGB8 -0.47 -6.1 -0.31 2.88e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs3770081 0.590 rs57367442 chr2:86453398 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -0.72 -7.66 -0.38 1.98e-13 Facial emotion recognition (sad faces); LIHC cis rs13177918 0.603 rs2343806 chr5:149831985 A/T cg14059543 chr5:149831962 NA -0.48 -7.5 -0.38 5.53e-13 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs2292096 1.000 rs16847193 chr1:200739337 T/A cg11814564 chr1:200748674 CAMSAP1L1 -0.47 -6.12 -0.31 2.57e-9 Epilepsy; LIHC cis rs2991971 1.000 rs606542 chr1:46013933 T/C cg15605315 chr1:45957053 TESK2 0.45 5.89 0.3 9.42e-9 High light scatter reticulocyte count; LIHC cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg08645402 chr16:4508243 NA 0.39 7.4 0.37 1.09e-12 Schizophrenia; LIHC cis rs6430585 0.528 rs12476127 chr2:136763242 A/G cg25344623 chr2:136566232 LCT -0.37 -5.88 -0.3 9.9e-9 Corneal structure; LIHC cis rs9378688 0.654 rs2505661 chr6:2326285 G/A cg12303981 chr6:2244766 GMDS -0.43 -6.08 -0.31 3.21e-9 Caudate nucleus volume; LIHC cis rs9660992 0.548 rs1172152 chr1:205220718 T/A cg21545522 chr1:205238299 TMCC2 0.4 7.72 0.39 1.33e-13 Mean corpuscular volume;Mean platelet volume; LIHC cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg10712668 chr3:52740153 GLT8D1;SPCS1 -0.54 -7.8 -0.39 7.56e-14 Bipolar disorder; LIHC cis rs34779708 0.868 rs2384352 chr10:35492832 A/G cg03585969 chr10:35415529 CREM 0.82 11.89 0.54 1.56e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg06601766 chr17:61851465 DDX42;CCDC47 0.47 7.4 0.37 1.05e-12 Prudent dietary pattern; LIHC cis rs227584 0.663 rs2040810 chr17:42243771 C/T cg08499158 chr17:42289980 UBTF 0.41 6.62 0.34 1.4e-10 Bone mineral density (hip);Bone mineral density; LIHC cis rs7412746 0.611 rs11204747 chr1:150927152 A/G cg15448220 chr1:150897856 SETDB1 -0.38 -6.18 -0.32 1.77e-9 Melanoma; LIHC cis rs10503871 0.685 rs7824823 chr8:30322735 G/T cg26383811 chr8:30366931 RBPMS -0.45 -7.8 -0.39 7.52e-14 Metabolite levels (X-11787); LIHC cis rs8005677 1.000 rs7145494 chr14:23399790 T/C cg25600027 chr14:23388339 RBM23 -0.41 -5.91 -0.3 8.06e-9 Cognitive ability (multi-trait analysis); LIHC cis rs11764590 0.694 rs11762413 chr7:2090387 C/G cg23422044 chr7:1970798 MAD1L1 -0.54 -8.5 -0.42 5.96e-16 Neuroticism; LIHC cis rs1552244 0.882 rs13063098 chr3:10009919 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.81 10.9 0.51 6.15e-24 Alzheimer's disease; LIHC cis rs7903847 0.642 rs9888117 chr10:99159963 C/G cg08345082 chr10:99160200 RRP12 -0.38 -6.45 -0.33 3.72e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg03806693 chr22:41940476 POLR3H 0.96 10.38 0.49 4.04e-22 Crohn's disease;Inflammatory bowel disease; LIHC trans rs7395662 0.534 rs12418219 chr11:48988091 G/T cg03929089 chr4:120376271 NA -0.44 -6.54 -0.33 2.28e-10 HDL cholesterol; LIHC cis rs6840360 1.000 rs1105535 chr4:152605170 A/G cg22705602 chr4:152727874 NA -0.29 -6.06 -0.31 3.6e-9 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg06108461 chr20:60628389 TAF4 -1.02 -18.11 -0.7 7e-52 Body mass index; LIHC cis rs449303 1 rs449303 chr14:60605788 A/G cg23283614 chr14:60632532 DHRS7 0.71 7.53 0.38 4.6e-13 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs826838 0.967 rs11169169 chr12:39093153 A/C cg26384229 chr12:38710491 ALG10B 0.88 11.66 0.53 1.12e-26 Heart rate; LIHC cis rs763121 0.853 rs2205802 chr22:39046327 T/C cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg22963979 chr7:1858916 MAD1L1 -0.4 -6.38 -0.33 5.92e-10 Bipolar disorder and schizophrenia; LIHC cis rs2576037 0.501 rs8089938 chr18:44459497 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.53 7.83 0.39 6.09e-14 Personality dimensions; LIHC cis rs10791097 0.694 rs3190331 chr11:130748131 C/T cg14779329 chr11:130786720 SNX19 -0.38 -5.84 -0.3 1.21e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1577917 1.000 rs35761942 chr6:86629504 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -10.55 -0.5 1.01e-22 Response to antipsychotic treatment; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.46 -6.61 -0.34 1.51e-10 Lymphocyte counts; LIHC cis rs13161895 1.000 rs1102191 chr5:179416210 C/T cg02702477 chr5:179499311 RNF130 0.75 10.32 0.49 6.59e-22 LDL cholesterol; LIHC cis rs12586317 0.547 rs76770287 chr14:35487210 C/A cg16230307 chr14:35515116 FAM177A1 0.79 13.35 0.59 5.37e-33 Psoriasis; LIHC cis rs9359856 0.623 rs1179903 chr6:90321736 G/T cg13799429 chr6:90582589 CASP8AP2 -0.74 -8.43 -0.41 1e-15 Bipolar disorder; LIHC cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg27211696 chr2:191398769 TMEM194B -0.67 -11.16 -0.52 7.28e-25 Pulse pressure; LIHC trans rs10411161 0.810 rs60981935 chr19:52385281 C/T cg22319618 chr22:45562946 NUP50 -0.59 -7.01 -0.35 1.28e-11 Breast cancer; LIHC cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg11766577 chr21:47581405 C21orf56 -0.37 -5.84 -0.3 1.23e-8 Testicular germ cell tumor; LIHC cis rs9389248 0.708 rs7750574 chr6:135350932 G/C cg24558204 chr6:135376177 HBS1L 0.62 10.57 0.5 8.43e-23 High light scatter reticulocyte percentage of red cells; LIHC cis rs2455799 0.573 rs2654650 chr3:15779214 C/T cg12698662 chr3:15914712 MIR563 -0.4 -7.52 -0.38 4.88e-13 Mean platelet volume; LIHC cis rs2153535 0.580 rs1119690 chr6:8460660 G/A cg07606381 chr6:8435919 SLC35B3 0.8 11.92 0.54 1.28e-27 Motion sickness; LIHC cis rs2070488 0.965 rs6796845 chr3:38567771 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.88 -14.56 -0.62 1.01e-37 Electrocardiographic conduction measures; LIHC cis rs9503598 0.521 rs4959834 chr6:3436691 A/C cg00476032 chr6:3446245 SLC22A23 -0.33 -5.96 -0.31 6.12e-9 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14932796 chr17:55038330 COIL 0.45 7.4 0.37 1.09e-12 Cognitive function; LIHC cis rs798766 1.000 rs798719 chr4:1698183 C/T cg15202627 chr4:1685555 FAM53A 0.48 5.74 0.3 2.15e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs12995491 0.731 rs55705009 chr2:88500718 T/G cg07952391 chr2:88470173 THNSL2 -0.41 -5.72 -0.3 2.29e-8 Response to metformin (IC50); LIHC trans rs1430128 0.534 rs1430130 chr2:218608763 G/T cg19873842 chr12:26204575 RASSF8 -0.57 -6.1 -0.31 2.85e-9 Congenital heart disease (inherited effect); LIHC cis rs611744 0.506 rs13280454 chr8:109263240 A/G cg18478394 chr8:109455254 TTC35 0.42 7.24 0.36 2.98e-12 Dupuytren's disease; LIHC cis rs1434579 0.865 rs1434573 chr19:44923277 A/G cg15540054 chr19:45004280 ZNF180 0.55 7.51 0.38 5.17e-13 Tuberculosis; LIHC cis rs35146811 0.844 rs13223792 chr7:99675659 T/G cg13334819 chr7:99746414 C7orf59 -0.57 -8.3 -0.41 2.45e-15 Coronary artery disease; LIHC cis rs7412746 0.646 rs1972060 chr1:150937594 T/C cg18016565 chr1:150552671 MCL1 0.49 9.31 0.45 1.63e-18 Melanoma; LIHC cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg00280220 chr17:61926910 NA 0.44 6.99 0.35 1.48e-11 Prudent dietary pattern; LIHC cis rs769267 0.930 rs6909 chr19:19619542 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.5 7.6 0.38 2.93e-13 Tonsillectomy; LIHC cis rs11583043 1.000 rs2391573 chr1:101489698 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 8.73 0.43 1.12e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs4919694 1.000 rs7099987 chr10:104807926 C/T cg04362960 chr10:104952993 NT5C2 1.14 8.87 0.43 4.02e-17 Arsenic metabolism; LIHC cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.86 -10.01 -0.48 7.45e-21 Platelet count; LIHC cis rs17331151 0.573 rs13080929 chr3:52885112 A/C cg04865290 chr3:52927548 TMEM110 -0.48 -7.14 -0.36 5.65e-12 Immune reponse to smallpox (secreted IL-2); LIHC cis rs28595532 0.748 rs55949457 chr4:119336174 A/G cg21605333 chr4:119757512 SEC24D 0.98 8.27 0.41 3.01e-15 Cannabis dependence symptom count; LIHC cis rs7592578 0.508 rs10931451 chr2:191270888 G/A cg27211696 chr2:191398769 TMEM194B -0.46 -6.1 -0.31 2.83e-9 Diastolic blood pressure; LIHC cis rs6728642 0.908 rs9973669 chr2:97679094 T/C cg26665480 chr2:98280029 ACTR1B -0.67 -6.09 -0.31 3.05e-9 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs910316 0.737 rs108622 chr14:75481908 A/G cg08847533 chr14:75593920 NEK9 -0.88 -18.1 -0.7 8.06e-52 Height; LIHC cis rs12220238 0.818 rs10430521 chr10:75913590 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.69 6.54 0.33 2.22e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs7903847 0.642 rs10882908 chr10:99134970 T/C cg20016023 chr10:99160130 RRP12 -0.41 -6.48 -0.33 3.16e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg16740167 chr1:27560800 WDTC1 0.41 6.25 0.32 1.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1707322 0.752 rs28623463 chr1:46170758 A/C cg06784218 chr1:46089804 CCDC17 0.41 7.2 0.36 3.87e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6121246 0.909 rs6058460 chr20:30363071 G/A cg13852791 chr20:30311386 BCL2L1 0.95 9.7 0.46 8.02e-20 Mean corpuscular hemoglobin; LIHC cis rs7044106 0.762 rs1530370 chr9:123424552 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.71 11.38 0.52 1.14e-25 Hip circumference adjusted for BMI; LIHC cis rs249954 0.559 rs35586 chr16:23677006 A/G cg09867953 chr16:23706666 ERN2 0.37 6.22 0.32 1.45e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs6701037 0.681 rs1057246 chr1:175127534 C/G cg00321850 chr1:175162397 KIAA0040 0.38 6.18 0.32 1.85e-9 Alcohol dependence; LIHC cis rs57502260 0.704 rs60538784 chr11:68386735 G/A cg20283391 chr11:68216788 NA -0.49 -5.99 -0.31 5.26e-9 Total body bone mineral density (age 45-60); LIHC cis rs4803468 1.000 rs4803468 chr19:41922352 A/G cg14132834 chr19:41945861 ATP5SL -0.44 -6.52 -0.33 2.5e-10 Height; LIHC trans rs4906332 1.000 rs8012127 chr14:103942762 G/A cg17675199 chr6:35436792 RPL10A 0.35 6.86 0.35 3.26e-11 Coronary artery disease; LIHC cis rs11676348 0.935 rs13007992 chr2:218964051 G/T cg00012203 chr2:219082015 ARPC2 -0.53 -7.06 -0.36 9.23e-12 Ulcerative colitis; LIHC cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg07677032 chr17:61819896 STRADA -0.44 -6.3 -0.32 9.06e-10 Prudent dietary pattern; LIHC trans rs1432089 0.689 rs62344301 chr4:171784950 T/G cg02328223 chr3:127541927 MGLL -0.42 -6.06 -0.31 3.55e-9 Endometriosis; LIHC cis rs2404602 0.647 rs12898416 chr15:77042292 C/G cg23625390 chr15:77176239 SCAPER -0.54 -8.98 -0.44 1.81e-17 Blood metabolite levels; LIHC cis rs9425766 0.640 rs3791020 chr1:173813197 A/G cg06124660 chr1:173389066 NA 0.34 6.41 0.33 4.84e-10 Life satisfaction; LIHC cis rs1816752 0.905 rs6490927 chr13:25013940 C/G cg22771759 chr13:24902376 NA 0.32 6.74 0.34 6.76e-11 Obesity-related traits; LIHC cis rs10848704 0.525 rs4765709 chr12:2883637 C/T cg19995117 chr12:2880862 NA 0.33 6.21 0.32 1.5e-9 Quantitative traits; LIHC cis rs8017423 0.967 rs1959002 chr14:90670994 T/A cg14092571 chr14:90743983 NA -0.36 -5.74 -0.3 2.04e-8 Mortality in heart failure; LIHC cis rs59043219 1 rs59043219 chr1:209970610 G/A cg23283495 chr1:209979779 IRF6 0.44 7.67 0.38 1.76e-13 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); LIHC cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg00166722 chr3:10149974 C3orf24 0.48 5.81 0.3 1.41e-8 Alzheimer's disease; LIHC cis rs9309473 0.607 rs6546826 chr2:73599808 A/G cg20560298 chr2:73613845 ALMS1 0.43 6.85 0.35 3.36e-11 Metabolite levels; LIHC cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg10802521 chr3:52805072 NEK4 -0.45 -7.6 -0.38 2.92e-13 Bipolar disorder; LIHC cis rs13108904 0.901 rs66987549 chr4:1272617 C/T cg05025164 chr4:1340916 KIAA1530 0.53 8.07 0.4 1.24e-14 Obesity-related traits; LIHC cis rs1801251 1.000 rs9653383 chr2:233670380 A/C cg25237894 chr2:233734115 C2orf82 -0.59 -11.31 -0.52 2.15e-25 Coronary artery disease; LIHC cis rs13256369 0.708 rs10903310 chr8:8589687 A/C cg17143192 chr8:8559678 CLDN23 -0.65 -9.94 -0.47 1.3e-20 Obesity-related traits; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg04234412 chr22:24373322 LOC391322 -0.71 -10.5 -0.49 1.48e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs80282103 0.618 rs7100114 chr10:1110231 A/G cg08668510 chr10:1095578 IDI1 0.68 6.62 0.34 1.4e-10 Glomerular filtration rate (creatinine); LIHC cis rs11252926 0.574 rs7068976 chr10:453112 A/G cg16346588 chr10:242978 ZMYND11 0.39 5.88 0.3 9.59e-9 Psychosis in Alzheimer's disease; LIHC cis rs611744 0.631 rs627392 chr8:109254677 C/T cg21045802 chr8:109455806 TTC35 0.59 10.4 0.49 3.38e-22 Dupuytren's disease; LIHC cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg00091569 chr3:40428383 ENTPD3 0.4 6.66 0.34 1.08e-10 Renal cell carcinoma; LIHC cis rs5769765 0.913 rs4824111 chr22:50284305 A/G cg26441486 chr22:50317300 CRELD2 -0.37 -6.03 -0.31 4.18e-9 Schizophrenia; LIHC cis rs1434579 0.865 rs12980701 chr19:44948014 C/A cg15540054 chr19:45004280 ZNF180 0.57 7.85 0.39 5.46e-14 Tuberculosis; LIHC cis rs546131 0.600 rs7946699 chr11:34820069 G/C cg06937548 chr11:34938143 PDHX;APIP 0.48 6.37 0.33 6.14e-10 Lung disease severity in cystic fibrosis; LIHC trans rs2727020 0.523 rs4115783 chr11:49556026 G/A cg18944383 chr4:111397179 ENPEP -0.34 -7.97 -0.4 2.41e-14 Coronary artery disease; LIHC cis rs924607 1.000 rs4045344 chr5:595870 G/T cg24163568 chr5:669837 TPPP -0.42 -8.57 -0.42 3.57e-16 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs5769765 0.773 rs9616208 chr22:50313359 G/A cg02269571 chr22:50332266 NA -0.76 -9.94 -0.47 1.3e-20 Schizophrenia; LIHC cis rs1144333 1.000 rs1890967 chr1:76459544 T/C cg22875332 chr1:76189707 ACADM 0.41 6.44 0.33 4.05e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs3096299 0.967 rs28575874 chr16:89469890 C/T cg06640241 chr16:89574553 SPG7 0.67 10.86 0.51 8.07e-24 Multiple myeloma (IgH translocation); LIHC cis rs769267 0.965 rs4808200 chr19:19554803 C/T cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 6.02 0.31 4.58e-9 Tonsillectomy; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19794706 chr14:75643232 TMED10 0.4 6.06 0.31 3.58e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg08888203 chr3:10149979 C3orf24 0.56 6.71 0.34 8.24e-11 Alzheimer's disease; LIHC cis rs17270561 0.779 rs12210620 chr6:25884785 T/C cg16482183 chr6:26056742 HIST1H1C 0.64 7.77 0.39 9.17e-14 Iron status biomarkers; LIHC cis rs6963495 0.818 rs1721498 chr7:105178819 A/C cg19920283 chr7:105172520 RINT1 -0.75 -8.65 -0.42 2.05e-16 Bipolar disorder (body mass index interaction); LIHC cis rs903552 1.000 rs8043205 chr15:102005749 A/G cg06707286 chr15:102010195 PCSK6 -0.44 -6.22 -0.32 1.43e-9 Diabetic kidney disease; LIHC cis rs950776 0.518 rs12907169 chr15:78825498 G/C cg06917634 chr15:78832804 PSMA4 0.94 14.37 0.61 5.81e-37 Sudden cardiac arrest; LIHC cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg07424592 chr7:64974309 NA 0.79 9.12 0.44 6.72e-18 Diabetic kidney disease; LIHC trans rs11088226 0.645 rs7281844 chr21:33932435 T/C cg09050820 chr6:167586206 TCP10L2 0.86 13.47 0.59 1.75e-33 Gastritis; LIHC cis rs3806843 0.838 rs2563289 chr5:140122766 T/A cg26395211 chr5:140044315 WDR55 0.39 5.96 0.31 6.16e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs933688 1.000 rs61612071 chr5:90741470 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.82 16.39 0.66 5.8e-45 Smoking behavior; LIHC cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg05590025 chr7:65112418 INTS4L2 -0.62 -6.82 -0.35 4.26e-11 Diabetic kidney disease; LIHC cis rs17685 0.753 rs6976532 chr7:75681094 A/G cg04592579 chr7:75616294 TMEM120A 0.39 6.87 0.35 3.1e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1506636 0.646 rs805776 chr7:123212561 T/C cg03229431 chr7:123269106 ASB15 -0.45 -8.7 -0.43 1.45e-16 Plateletcrit;Platelet count; LIHC trans rs1005277 0.522 rs289645 chr10:37943642 T/C cg27523141 chr10:43048294 ZNF37B 0.35 6.08 0.31 3.24e-9 Extrinsic epigenetic age acceleration; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg27572529 chr10:21823470 MLLT10 -0.47 -6.63 -0.34 1.28e-10 Longevity; LIHC cis rs4555082 0.718 rs75139030 chr14:105710853 A/AG cg10792982 chr14:105748885 BRF1 0.49 6.35 0.32 6.85e-10 Mean platelet volume;Platelet distribution width; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg22586474 chr7:931148 C7orf20 0.5 6.67 0.34 1.02e-10 Hepatitis; LIHC cis rs7412746 0.611 rs111842513 chr1:150712926 G/A cg15448220 chr1:150897856 SETDB1 0.41 6.46 0.33 3.59e-10 Melanoma; LIHC cis rs4819052 0.807 rs28715237 chr21:46673768 C/G cg22633049 chr21:46681294 NA -0.36 -6.29 -0.32 9.93e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7296418 0.699 rs1109559 chr12:123757861 C/T cg05973401 chr12:123451056 ABCB9 0.41 6.2 0.32 1.59e-9 Platelet count; LIHC cis rs9902453 0.967 rs56129908 chr17:28421382 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.62 9.47 0.46 4.62e-19 Coffee consumption (cups per day); LIHC cis rs28493229 0.522 rs17713068 chr19:41270055 A/C cg21869046 chr19:41225005 ITPKC 0.45 6.33 0.32 7.62e-10 Kawasaki disease; LIHC cis rs738322 0.555 rs5750548 chr22:38547016 C/A cg25457927 chr22:38595422 NA -0.41 -10.14 -0.48 2.66e-21 Cutaneous nevi; LIHC cis rs826838 0.967 rs826870 chr12:39120250 G/A cg13010199 chr12:38710504 ALG10B -0.42 -5.99 -0.31 5.26e-9 Heart rate; LIHC cis rs7647973 1.000 rs11719762 chr3:49409002 G/C cg07636037 chr3:49044803 WDR6 0.5 6.22 0.32 1.45e-9 Menarche (age at onset); LIHC cis rs903552 1.000 rs34937195 chr15:102003631 C/A cg25677261 chr15:102009856 PCSK6 -0.43 -5.92 -0.3 7.76e-9 Diabetic kidney disease; LIHC cis rs7208859 0.623 rs76633166 chr17:29113365 C/T cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs17685 0.712 rs6464994 chr7:75784668 C/T cg16684958 chr7:75615977 POR 0.4 6.57 0.33 1.87e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg04025307 chr7:1156635 C7orf50 0.55 8.93 0.43 2.7e-17 Longevity;Endometriosis; LIHC cis rs6964587 0.869 rs6964050 chr7:91482418 C/T cg17063962 chr7:91808500 NA -0.95 -18.12 -0.7 6.28e-52 Breast cancer; LIHC cis rs3741151 1.000 rs79038783 chr11:73038746 C/G cg17517138 chr11:73019481 ARHGEF17 0.95 6.95 0.35 1.85e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs7772486 0.754 rs6906258 chr6:146089356 A/G cg13319975 chr6:146136371 FBXO30 0.4 6.47 0.33 3.34e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg03264133 chr6:25882463 NA -0.6 -8.68 -0.42 1.63e-16 Blood metabolite levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17739026 chr1:27114420 PIGV -0.43 -6.06 -0.31 3.69e-9 Systolic blood pressure; LIHC cis rs1355223 0.902 rs12801509 chr11:34747336 G/T cg11058730 chr11:34937778 PDHX;APIP -0.48 -6.52 -0.33 2.5e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs1814175 0.676 rs1851859 chr11:49860405 A/T cg18944383 chr4:111397179 ENPEP 0.27 7.0 0.35 1.34e-11 Height; LIHC trans rs61931739 0.534 rs7310499 chr12:34212112 G/A cg26384229 chr12:38710491 ALG10B 0.59 7.57 0.38 3.5e-13 Morning vs. evening chronotype; LIHC trans rs1864585 0.520 rs7009920 chr8:10585162 C/T cg26278703 chr11:58910052 FAM111A -0.68 -6.31 -0.32 8.77e-10 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.59 8.49 0.42 6.22e-16 Lymphocyte counts; LIHC cis rs4819052 0.851 rs7275874 chr21:46671223 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 7.77 0.39 9.12e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9303401 0.573 rs62081879 chr17:57181524 C/T cg25039879 chr17:56429692 SUPT4H1 0.76 8.62 0.42 2.57e-16 Cognitive test performance; LIHC cis rs7647973 0.710 rs2029591 chr3:49646981 C/T cg03060546 chr3:49711283 APEH -0.61 -6.9 -0.35 2.61e-11 Menarche (age at onset); LIHC cis rs4819052 0.851 rs2838865 chr21:46712299 C/T cg22633049 chr21:46681294 NA -0.37 -6.17 -0.32 1.89e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7312933 0.966 rs7977365 chr12:42513127 G/A cg17420585 chr12:42539391 GXYLT1 -0.36 -5.89 -0.3 9.48e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7772486 0.846 rs9403767 chr6:146402386 G/T cg13319975 chr6:146136371 FBXO30 -0.4 -6.41 -0.33 4.74e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4803468 0.763 rs17318596 chr19:41937095 A/G cg14132834 chr19:41945861 ATP5SL -0.46 -6.9 -0.35 2.48e-11 Height; LIHC cis rs904251 0.861 rs914349 chr6:37484715 A/C cg01843034 chr6:37503916 NA -0.48 -7.89 -0.39 4.11e-14 Cognitive performance; LIHC cis rs2075371 0.933 rs2544191 chr7:133954248 A/G cg20476274 chr7:133979776 SLC35B4 0.75 12.92 0.57 2.25e-31 Mean platelet volume; LIHC cis rs208520 0.909 rs9453672 chr6:66991431 A/G cg07460842 chr6:66804631 NA 0.66 7.23 0.36 3.2e-12 Exhaled nitric oxide output; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg02675502 chr2:219264639 CTDSP1 0.42 6.08 0.31 3.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7100689 0.646 rs1538819 chr10:82122523 A/G cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs970821 1.000 rs4617136 chr8:124750451 G/A cg00283535 chr8:124749564 ANXA13 0.35 5.88 0.3 9.98e-9 Breast cancer; LIHC cis rs4975616 0.686 rs37008 chr5:1351538 C/T cg06550200 chr5:1325588 CLPTM1L -0.46 -6.81 -0.35 4.39e-11 Lung cancer; LIHC trans rs9951602 0.512 rs6506872 chr18:76649695 T/C cg02800362 chr5:177631904 HNRNPAB 0.67 10.57 0.5 8.78e-23 Obesity-related traits; LIHC cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg03517284 chr6:25882590 NA 0.6 8.24 0.41 3.74e-15 Blood metabolite levels; LIHC cis rs68170813 0.559 rs1018946 chr7:106851754 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs7917772 0.582 rs4917973 chr10:104333700 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.17e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs2243480 0.901 rs58207111 chr7:65486723 C/T cg10756647 chr7:56101905 PSPH 1.08 13.47 0.59 1.87e-33 Diabetic kidney disease; LIHC cis rs17401966 0.838 rs2182326 chr1:10385664 G/A cg15208524 chr1:10270712 KIF1B 0.38 5.74 0.3 2.12e-8 Hepatocellular carcinoma; LIHC cis rs4407350 1.000 rs4373013 chr22:44922248 C/T cg26276947 chr22:44892394 LDOC1L 0.34 6.35 0.32 6.7e-10 Intelligence (multi-trait analysis); LIHC cis rs754466 0.561 rs72806025 chr10:79707026 C/T cg17075019 chr10:79541650 NA -0.52 -5.86 -0.3 1.09e-8 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7582720 1.000 rs76461893 chr2:203865515 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.1 0.31 2.88e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg06640241 chr16:89574553 SPG7 0.86 16.46 0.66 3.15e-45 Multiple myeloma (IgH translocation); LIHC cis rs4665809 1.000 rs750452 chr2:26324995 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.75 -0.43 1.02e-16 Gut microbiome composition (summer); LIHC cis rs9473924 0.505 rs9463664 chr6:50902570 T/A cg14470998 chr6:50812995 TFAP2B 0.93 10.85 0.51 9.2e-24 Body mass index; LIHC cis rs2276314 0.947 rs4799831 chr18:33554775 A/G cg05985134 chr18:33552581 C18orf21 0.49 5.84 0.3 1.21e-8 Endometriosis;Drug-induced torsades de pointes; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg07677032 chr17:61819896 STRADA 0.43 6.39 0.33 5.57e-10 Prudent dietary pattern; LIHC cis rs9858542 0.953 rs9827021 chr3:49514764 C/A cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs1873147 0.569 rs59418037 chr15:63310871 A/G cg21584241 chr15:63341463 TPM1 0.44 6.38 0.33 5.9e-10 Orofacial clefts; LIHC cis rs9318086 0.534 rs1011362 chr13:24377157 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.35 5.79 0.3 1.57e-8 Myopia (pathological); LIHC cis rs11190604 1.000 rs4919469 chr10:102298855 C/A cg07080220 chr10:102295463 HIF1AN 0.53 7.61 0.38 2.76e-13 Palmitoleic acid (16:1n-7) levels; LIHC cis rs1707322 1.000 rs11211200 chr1:46288352 A/G cg03146154 chr1:46216737 IPP 0.48 7.91 0.39 3.65e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7927592 0.913 rs3824850 chr11:68341873 A/G cg20283391 chr11:68216788 NA -0.52 -7.78 -0.39 8.94e-14 Total body bone mineral density; LIHC cis rs1113500 0.933 rs11185261 chr1:108638703 G/A cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.87e-12 Growth-regulated protein alpha levels; LIHC cis rs3859192 0.539 rs2305481 chr17:38138624 G/A cg17344932 chr17:38183730 MED24;SNORD124 0.76 14.92 0.63 3.89e-39 White blood cell count; LIHC cis rs9948 0.748 rs62156223 chr2:97412167 T/C cg01990225 chr2:97406019 LMAN2L -0.81 -6.34 -0.32 7.31e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs28386778 0.863 rs3760252 chr17:61852186 G/C cg07677032 chr17:61819896 STRADA 0.43 6.14 0.32 2.23e-9 Prudent dietary pattern; LIHC cis rs8062405 0.655 rs7184597 chr16:28921809 T/C cg00204512 chr16:28754710 NA -0.36 -6.35 -0.32 6.99e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1059312 1.000 rs7135987 chr12:129280117 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 -0.73 -14.43 -0.62 3.3e-37 Systemic lupus erythematosus; LIHC cis rs6088590 0.648 rs6058105 chr20:33271719 C/T cg08999081 chr20:33150536 PIGU 0.65 12.62 0.56 3.04e-30 Coronary artery disease; LIHC cis rs12048904 0.505 rs6577209 chr1:101255080 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.49 8.12 0.4 8.63e-15 Multiple sclerosis; LIHC cis rs2412488 0.853 rs12508701 chr4:54353243 C/T cg22241045 chr4:54363911 LNX1 -0.4 -6.67 -0.34 1.03e-10 DNA methylation (variation); LIHC cis rs6500602 0.702 rs4786511 chr16:4571645 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.74 0.3 2.07e-8 Schizophrenia; LIHC cis rs7552167 0.925 rs3932666 chr1:24511566 G/A cg01960748 chr1:24522592 NA -0.77 -9.23 -0.45 2.8e-18 Psoriasis vulgaris; LIHC cis rs11608355 0.545 rs4766473 chr12:109900596 C/T cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs13118159 0.801 rs7664474 chr4:1329116 T/A cg16405210 chr4:1374714 KIAA1530 -0.52 -7.42 -0.37 9.56e-13 Longevity; LIHC cis rs2832191 0.692 rs2245734 chr21:30359965 C/T cg24692254 chr21:30365293 RNF160 0.85 15.07 0.63 1.06e-39 Dental caries; LIHC trans rs10411161 0.702 rs11879319 chr19:52389592 C/T cg22319618 chr22:45562946 NUP50 -0.64 -8.9 -0.43 3.24e-17 Breast cancer; LIHC cis rs2153535 0.580 rs4960412 chr6:8438261 G/C cg07606381 chr6:8435919 SLC35B3 0.79 11.67 0.53 1.03e-26 Motion sickness; LIHC cis rs3736485 0.966 rs2414113 chr15:51903896 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.21 -0.32 1.54e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1355223 0.583 rs1553757 chr11:34867089 G/A cg11058730 chr11:34937778 PDHX;APIP 0.73 12.62 0.56 2.98e-30 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg06238570 chr21:40685208 BRWD1 -0.54 -9.02 -0.44 1.4e-17 Cognitive function; LIHC cis rs9611519 0.894 rs8136923 chr22:41470522 G/A cg03806693 chr22:41940476 POLR3H -0.71 -7.89 -0.39 4.14e-14 Neuroticism; LIHC cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg17372223 chr3:52568218 NT5DC2 0.36 5.95 0.31 6.57e-9 Electroencephalogram traits; LIHC cis rs986417 0.818 rs4278669 chr14:60982075 T/C cg27398547 chr14:60952738 C14orf39 0.75 8.29 0.41 2.6e-15 Gut microbiota (bacterial taxa); LIHC cis rs9457247 0.534 rs12055488 chr6:167379570 A/G cg23791538 chr6:167370224 RNASET2 0.76 14.45 0.62 2.74e-37 Crohn's disease; LIHC cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs8005677 1.000 rs1956881 chr14:23394069 A/C cg07971674 chr14:23388846 RBM23 -0.4 -5.81 -0.3 1.45e-8 Cognitive ability (multi-trait analysis); LIHC cis rs1577917 0.740 rs2758843 chr6:86328431 A/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.34 -6.29 -0.32 9.44e-10 Response to antipsychotic treatment; LIHC cis rs2067615 0.524 rs1882543 chr12:107067160 A/G cg15890332 chr12:107067104 RFX4 -0.25 -5.89 -0.3 9.29e-9 Heart rate; LIHC cis rs10870270 1.000 rs7078692 chr10:133775370 T/A cg26149184 chr10:133730230 NA 0.47 7.51 0.38 5.31e-13 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg12311636 chr6:118886798 C6orf204 -0.56 -6.41 -0.33 4.89e-10 Renal cell carcinoma; LIHC cis rs3845702 0.736 rs72960660 chr2:180832482 A/G cg01881094 chr2:180872142 CWC22 1.13 9.9 0.47 1.74e-20 Schizophrenia; LIHC cis rs881375 0.678 rs9886724 chr9:123665019 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 6.4 0.33 5.18e-10 Rheumatoid arthritis; LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg11494091 chr17:61959527 GH2 0.35 5.8 0.3 1.53e-8 Height; LIHC trans rs13113518 0.812 rs12500601 chr4:56317656 T/G cg15358633 chr12:38710606 ALG10B 0.46 6.53 0.33 2.32e-10 Height; LIHC cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg21724239 chr8:58056113 NA 0.48 6.4 0.33 5.2400000000000005e-10 Developmental language disorder (linguistic errors); LIHC cis rs9733 0.566 rs112967224 chr1:150677263 G/A cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.06e-9 Tonsillectomy; LIHC cis rs62179067 0.708 rs11897059 chr2:179939876 A/G cg20701897 chr2:179586761 TTN 0.52 5.77 0.3 1.82e-8 Late-onset Alzheimer's disease; LIHC cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg26570765 chr4:1273065 NA 0.3 5.98 0.31 5.5e-9 Obesity-related traits; LIHC cis rs10193935 0.901 rs13413617 chr2:42537546 A/G cg27598129 chr2:42591480 NA -0.72 -10.94 -0.51 4.49e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs9596863 1.000 rs9596858 chr13:54421858 A/G ch.13.53330881F chr13:54432880 NA 0.44 5.94 0.31 6.85e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs9649465 1.000 rs55633050 chr7:123388474 A/G cg03229431 chr7:123269106 ASB15 -0.37 -7.98 -0.4 2.21e-14 Migraine; LIHC trans rs877282 0.898 rs12357016 chr10:765675 C/T cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs11148252 0.557 rs9536223 chr13:53233194 A/T cg12458913 chr13:53173898 NA 0.47 7.52 0.38 4.88e-13 Lewy body disease; LIHC cis rs11229555 0.645 rs12803648 chr11:58177561 G/T cg15696309 chr11:58395628 NA -0.65 -7.66 -0.38 1.9e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs7103648 0.669 rs7114011 chr11:47811309 A/C cg20307385 chr11:47447363 PSMC3 0.97 15.4 0.64 5.06e-41 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs6973256 0.637 rs12707116 chr7:133424909 C/T cg03336402 chr7:133662267 EXOC4 0.37 5.83 0.3 1.26e-8 Intelligence (multi-trait analysis); LIHC cis rs9325144 0.647 rs1386018 chr12:39104360 C/T cg26384229 chr12:38710491 ALG10B -0.41 -5.89 -0.3 9.16e-9 Morning vs. evening chronotype; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15190599 chr6:26156487 HIST1H1E -0.46 -6.69 -0.34 9.18e-11 Cognitive function; LIHC cis rs8077889 0.869 rs11713 chr17:41845824 A/G cg26893861 chr17:41843967 DUSP3 -0.83 -9.64 -0.46 1.31e-19 Triglycerides; LIHC cis rs7044106 0.791 rs10985004 chr9:123484937 T/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.61 9.2 0.45 3.61e-18 Hip circumference adjusted for BMI; LIHC cis rs754466 0.651 rs2004382 chr10:79650351 G/C cg17075019 chr10:79541650 NA -0.73 -10.75 -0.5 2.04e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7520050 0.966 rs61783200 chr1:46297403 T/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.08 0.31 3.26e-9 Red blood cell count;Reticulocyte count; LIHC cis rs6089829 0.962 rs6122347 chr20:61661866 C/T cg03213289 chr20:61660250 NA 0.5 8.91 0.43 3.07e-17 Prostate cancer (SNP x SNP interaction); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25632114 chr8:95732714 DPY19L4 0.45 6.75 0.34 6.39e-11 Cognitive function; LIHC cis rs78456975 0.527 rs10206020 chr2:1557927 A/G cg01028140 chr2:1542097 TPO -0.43 -6.78 -0.34 5.35e-11 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs6461049 0.608 rs3800923 chr7:2184673 A/G cg02951883 chr7:2050386 MAD1L1 -0.52 -8.19 -0.41 5.18e-15 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08452348 chr5:134303703 CATSPER3 0.45 6.95 0.35 1.87e-11 Cognitive function; LIHC trans rs11165623 0.765 rs11807955 chr1:96891623 C/T cg10631902 chr5:14652156 NA -0.34 -8.63 -0.42 2.36e-16 Hip circumference;Waist circumference; LIHC cis rs875971 0.862 rs13226170 chr7:65999298 G/A cg11764359 chr7:65958608 NA 0.78 13.61 0.59 5.2e-34 Aortic root size; LIHC cis rs6750795 0.870 rs6754952 chr2:232381245 G/T cg19187155 chr2:232395269 NMUR1 -0.66 -10.7 -0.5 3.12e-23 Height; LIHC cis rs12791968 0.765 rs12794751 chr11:44998769 C/G cg11846598 chr11:44996168 LOC221122 -0.41 -6.73 -0.34 7.03e-11 Inhibitory control; LIHC trans rs3749237 1.000 rs11130214 chr3:49735746 C/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.63 -10.02 -0.48 6.7e-21 Resting heart rate; LIHC cis rs2204008 0.641 rs66876045 chr12:38205713 G/A cg13010199 chr12:38710504 ALG10B 0.48 5.71 0.3 2.42e-8 Bladder cancer; LIHC cis rs8062405 0.755 rs4787457 chr16:28555400 A/G cg07382826 chr16:28625726 SULT1A1 0.49 7.68 0.38 1.74e-13 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg05368731 chr17:41323189 NBR1 0.7 11.39 0.52 1.11e-25 Menopause (age at onset); LIHC cis rs9640161 0.750 rs3735173 chr7:150020526 C/T cg21361702 chr7:150065534 REPIN1 0.46 6.3 0.32 9.13e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs10461617 0.541 rs832575 chr5:56161787 C/T cg24531977 chr5:56204891 C5orf35 -0.65 -7.56 -0.38 3.62e-13 Type 2 diabetes; LIHC cis rs1401999 0.668 rs6806313 chr3:183642152 G/C cg05044414 chr3:183734942 ABCC5 0.33 6.25 0.32 1.22e-9 Anterior chamber depth; LIHC cis rs55702914 0.712 rs10931778 chr2:198148922 C/T cg03934865 chr2:198174659 NA -0.4 -5.76 -0.3 1.91e-8 Major depression and alcohol dependence; LIHC cis rs651907 0.557 rs17347644 chr3:101547733 C/T cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.87 -0.3 1.04e-8 Colorectal cancer; LIHC cis rs738322 0.775 rs13056506 chr22:38580917 G/T cg25457927 chr22:38595422 NA 0.4 10.19 0.48 1.76e-21 Cutaneous nevi; LIHC cis rs67478160 0.634 rs941475 chr14:104240618 A/C cg08213375 chr14:104286397 PPP1R13B 0.51 9.81 0.47 3.51e-20 Schizophrenia; LIHC cis rs716804 0.593 rs7107021 chr11:10071810 T/C cg01453529 chr11:10209919 SBF2 -0.3 -5.75 -0.3 1.94e-8 Neuroticism; LIHC cis rs3015497 0.934 rs2934691 chr14:51121333 C/A cg09863266 chr14:51125203 SAV1 -0.43 -7.01 -0.35 1.24e-11 Mean platelet volume; LIHC trans rs6866721 0.740 rs35816306 chr5:116215882 G/A cg07571379 chr11:134631427 NA -0.29 -6.09 -0.31 2.97e-9 Body mass index; LIHC cis rs4450131 0.522 rs34336231 chr10:126355662 C/T cg20435097 chr10:126320824 FAM53B 0.67 12.28 0.55 5.98e-29 White blood cell count (basophil); LIHC trans rs11098499 0.754 rs11098502 chr4:120252063 T/A cg25214090 chr10:38739885 LOC399744 0.51 8.25 0.41 3.48e-15 Corneal astigmatism; LIHC cis rs13108904 0.901 rs12641735 chr4:1304434 G/C cg05025164 chr4:1340916 KIAA1530 0.53 8.33 0.41 2.03e-15 Obesity-related traits; LIHC cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg23172400 chr8:95962367 TP53INP1 -0.43 -10.12 -0.48 3.06e-21 Type 2 diabetes; LIHC cis rs11577318 0.812 rs3795683 chr1:26632831 C/A cg00852783 chr1:26633632 UBXN11 0.41 6.64 0.34 1.2e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs6845999 1.000 rs7699073 chr4:145542668 C/G cg18349516 chr17:62503735 CCDC45;DDX5 -0.45 -6.19 -0.32 1.74e-9 Height; LIHC cis rs4808199 0.947 rs4808960 chr19:19574277 G/C cg03709012 chr19:19516395 GATAD2A 1.09 19.63 0.73 5.64e-58 Nonalcoholic fatty liver disease; LIHC cis rs7772486 0.875 rs2748485 chr6:146332421 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -5.95 -0.31 6.66e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7903847 0.642 rs10882913 chr10:99141845 C/T cg08345082 chr10:99160200 RRP12 -0.38 -6.37 -0.33 6.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs5753618 0.509 rs5997902 chr22:31583007 A/G cg07713946 chr22:31675144 LIMK2 -0.42 -7.42 -0.37 9.12e-13 Colorectal cancer; LIHC cis rs6489785 0.509 rs3213570 chr12:121222411 C/G cg02419362 chr12:121203948 SPPL3 0.33 5.71 0.3 2.45e-8 Longevity;Allergic disease (asthma, hay fever or eczema); LIHC cis rs4843747 0.636 rs4075597 chr16:88107590 C/A cg06050784 chr16:88016603 BANP 0.36 6.4 0.33 5.12e-10 Menopause (age at onset); LIHC cis rs6450176 0.904 rs6889847 chr5:53303452 G/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.86 -0.63 6.69e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs9457247 1.000 rs239935 chr6:167411788 G/A cg23791538 chr6:167370224 RNASET2 -0.55 -8.51 -0.42 5.5e-16 Crohn's disease; LIHC cis rs4713118 0.516 rs7739216 chr6:28079946 G/T cg23485639 chr6:28045615 ZNF165 0.44 5.78 0.3 1.71e-8 Parkinson's disease; LIHC cis rs897984 0.520 rs4889614 chr16:30862135 G/A cg02466173 chr16:30829666 NA 0.48 7.23 0.36 3.15e-12 Dementia with Lewy bodies; LIHC cis rs10791323 0.576 rs4937840 chr11:133734322 C/G cg06766960 chr11:133703094 NA -0.6 -10.02 -0.48 6.75e-21 Childhood ear infection; LIHC cis rs6582630 0.537 rs1829579 chr12:38420555 A/G cg26384229 chr12:38710491 ALG10B 0.61 8.48 0.42 6.79e-16 Drug-induced liver injury (flucloxacillin); LIHC cis rs244293 0.965 rs244298 chr17:53241387 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.44 -6.19 -0.32 1.77e-9 Menarche (age at onset); LIHC cis rs317689 0.819 rs317664 chr12:69704747 C/A cg14784868 chr12:69753453 YEATS4 0.6 8.83 0.43 5.38e-17 Response to diuretic therapy; LIHC cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg00684032 chr4:1343700 KIAA1530 -0.35 -5.79 -0.3 1.61e-8 Obesity-related traits; LIHC cis rs722599 0.683 rs8011071 chr14:75286705 T/C cg11812906 chr14:75593930 NEK9 0.41 6.14 0.31 2.32e-9 IgG glycosylation; LIHC cis rs7511006 1.000 rs7364173 chr22:50681029 C/T cg16473166 chr22:50639996 SELO -0.47 -6.77 -0.34 5.57e-11 Obesity-related traits; LIHC cis rs796364 0.806 rs112305133 chr2:201010380 A/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.54 -6.15 -0.32 2.16e-9 Schizophrenia; LIHC cis rs372883 0.648 rs4817279 chr21:30638285 T/C cg08807101 chr21:30365312 RNF160 -0.5 -5.72 -0.3 2.31e-8 Pancreatic cancer; LIHC cis rs2286885 1.000 rs2286886 chr9:129246177 T/C cg15282417 chr9:129245246 FAM125B 0.41 6.58 0.34 1.79e-10 Intraocular pressure; LIHC cis rs6430585 0.528 rs79826902 chr2:136670419 G/A cg07305463 chr2:136567211 LCT -0.39 -5.98 -0.31 5.48e-9 Corneal structure; LIHC cis rs11577318 0.796 rs4625269 chr1:26626967 C/A cg18121669 chr1:26560928 CCDC21 0.5 8.0 0.4 1.91e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs1395 0.744 rs4665962 chr2:27515105 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -5.94 -0.31 7.05e-9 Blood metabolite levels; LIHC cis rs10463316 0.817 rs13359941 chr5:150802118 C/T cg03212797 chr5:150827313 SLC36A1 -0.41 -6.2 -0.32 1.6e-9 Metabolite levels (Pyroglutamine); LIHC trans rs2832191 0.740 rs2853830 chr21:30416824 A/G cg14791747 chr16:20752902 THUMPD1 -0.49 -6.87 -0.35 3.03e-11 Dental caries; LIHC cis rs7818688 0.697 rs11784140 chr8:95987480 G/T cg16049864 chr8:95962084 TP53INP1 0.59 6.42 0.33 4.5e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg03122164 chr19:39421160 MRPS12;SARS2 -0.5 -6.25 -0.32 1.2e-9 Systolic blood pressure; LIHC cis rs72627123 0.867 rs73303122 chr14:74486797 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 6.02 0.31 4.59e-9 Morning vs. evening chronotype; LIHC cis rs4925386 0.808 rs1760073 chr20:60926106 A/G cg06026331 chr20:60912101 LAMA5 -0.5 -8.6 -0.42 2.98e-16 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2404602 0.669 rs1875884 chr15:76638161 C/T cg23625390 chr15:77176239 SCAPER 0.36 5.92 0.3 7.81e-9 Blood metabolite levels; LIHC cis rs2197308 0.765 rs11182992 chr12:37935572 G/C cg13010199 chr12:38710504 ALG10B 0.5 5.79 0.3 1.6e-8 Morning vs. evening chronotype; LIHC cis rs875971 0.895 rs6460278 chr7:65662736 T/C cg18252515 chr7:66147081 NA 0.43 6.16 0.32 2.08e-9 Aortic root size; LIHC cis rs10791097 0.690 rs12284540 chr11:130729772 T/C cg12179176 chr11:130786555 SNX19 0.74 11.55 0.53 2.87e-26 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1419980 0.730 rs11561265 chr12:7744090 C/T cg10578777 chr12:7781093 NA -0.39 -5.74 -0.3 2.04e-8 HDL cholesterol levels; LIHC cis rs7635838 0.686 rs347589 chr3:11288419 A/G cg00170343 chr3:11313890 ATG7 0.54 8.08 0.4 1.12e-14 HDL cholesterol; LIHC cis rs17095355 1.000 rs9630102 chr10:111738662 A/T cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.85 -0.3 1.18e-8 Biliary atresia; LIHC trans rs7615952 0.543 rs4645102 chr3:125424441 A/G cg07211511 chr3:129823064 LOC729375 -0.47 -6.36 -0.33 6.32e-10 Blood pressure (smoking interaction); LIHC cis rs2273669 0.588 rs78276890 chr6:109305299 G/A cg05315195 chr6:109294784 ARMC2 -0.52 -5.73 -0.3 2.24e-8 Prostate cancer; LIHC cis rs11655198 1 rs11655198 chr17:38026169 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.17 0.36 4.67e-12 Asthma; LIHC cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg16822855 chr3:40428330 ENTPD3 0.34 6.19 0.32 1.73e-9 Renal cell carcinoma; LIHC trans rs2727020 0.556 rs2866365 chr11:49390731 A/G cg03929089 chr4:120376271 NA -0.68 -9.87 -0.47 2.27e-20 Coronary artery disease; LIHC cis rs68170813 0.559 rs7793594 chr7:106891829 C/T cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs7618501 0.633 rs6792892 chr3:49995518 T/C cg21659725 chr3:3221576 CRBN 0.71 11.58 0.53 2.13e-26 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.747 rs9990115 chr3:160838412 C/G cg03342759 chr3:160939853 NMD3 -0.68 -8.31 -0.41 2.36e-15 Morning vs. evening chronotype; LIHC cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg21724239 chr8:58056113 NA 0.58 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs79387448 0.745 rs17027442 chr2:103164948 A/G cg09003973 chr2:102972529 NA -0.9 -7.68 -0.38 1.67e-13 Gut microbiota (bacterial taxa); LIHC cis rs7618501 1.000 rs2271961 chr3:49878113 C/T cg24110177 chr3:50126178 RBM5 0.44 6.93 0.35 2.13e-11 Intelligence (multi-trait analysis); LIHC cis rs17253792 0.915 rs76952651 chr14:56188994 G/A cg01858014 chr14:56050164 KTN1 -0.74 -7.58 -0.38 3.18e-13 Putamen volume; LIHC trans rs8073060 0.586 rs4796098 chr17:33913436 T/C cg19694781 chr19:47549865 TMEM160 1.26 13.03 0.58 9e-32 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs12478296 1.000 rs55742408 chr2:243041077 G/A cg06360820 chr2:242988706 NA -0.84 -12.02 -0.55 5.15e-28 Obesity-related traits; LIHC cis rs3749237 0.595 rs4855839 chr3:49507847 G/A cg02487422 chr3:49467188 NICN1 0.4 6.25 0.32 1.26e-9 Resting heart rate; LIHC cis rs3820068 0.603 rs3795763 chr1:15959977 C/T cg17385448 chr1:15911702 AGMAT 0.34 5.83 0.3 1.26e-8 Systolic blood pressure; LIHC cis rs7107174 0.901 rs4945275 chr11:78119822 G/A cg02023728 chr11:77925099 USP35 0.34 6.37 0.33 6.05e-10 Testicular germ cell tumor; LIHC cis rs8016982 0.674 rs6574631 chr14:81675772 C/T cg01989461 chr14:81687754 GTF2A1 0.71 15.06 0.63 1.12e-39 Schizophrenia; LIHC cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg21448741 chr8:58168803 NA 0.33 5.86 0.3 1.11e-8 Developmental language disorder (linguistic errors); LIHC cis rs2120019 0.938 rs59094290 chr15:75308561 G/T cg11632617 chr15:75315747 PPCDC -0.48 -6.75 -0.34 6.34e-11 Blood trace element (Zn levels); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg17767933 chr8:141541054 NA 0.41 6.06 0.31 3.6e-9 Longevity; LIHC cis rs9486715 0.867 rs9384585 chr6:96875664 C/T cg06623918 chr6:96969491 KIAA0776 0.86 14.92 0.63 4.06e-39 Headache; LIHC cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg11941060 chr3:133502564 NA -0.4 -5.95 -0.31 6.68e-9 Iron status biomarkers; LIHC cis rs425277 0.583 rs4648807 chr1:2040898 A/G cg04315214 chr1:2043799 PRKCZ 0.36 5.86 0.3 1.06e-8 Height; LIHC cis rs8062405 1.000 rs62036657 chr16:28844365 G/A cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs1843834 0.505 rs940317 chr2:225358118 C/T cg22455342 chr2:225449267 CUL3 0.58 8.45 0.42 8.34e-16 IgE levels in asthmatics (D.p. specific); LIHC cis rs1538970 0.847 rs781230 chr1:45880751 C/T cg05343316 chr1:45956843 TESK2 -0.52 -7.63 -0.38 2.32e-13 Platelet count; LIHC cis rs6088590 1.000 rs6088607 chr20:33378733 C/T cg06115741 chr20:33292138 TP53INP2 0.57 7.86 0.39 5.19e-14 Coronary artery disease; LIHC cis rs2404602 0.692 rs12594556 chr15:77165363 G/A cg03037974 chr15:76606532 NA 0.73 14.33 0.61 8.54e-37 Blood metabolite levels; LIHC cis rs10791097 0.592 rs4936122 chr11:130734264 A/C cg12179176 chr11:130786555 SNX19 0.81 13.22 0.58 1.68e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC trans rs7674212 0.540 rs2720469 chr4:104086484 C/T cg16471864 chr4:38666270 KLF3;FLJ13197 -0.45 -6.34 -0.32 7.18e-10 Type 2 diabetes; LIHC cis rs909002 0.962 rs7537646 chr1:32135495 G/A cg13919466 chr1:32135498 COL16A1 -0.35 -6.46 -0.33 3.66e-10 Intelligence (multi-trait analysis); LIHC cis rs12893668 0.703 rs2274267 chr14:104029449 G/A cg24130564 chr14:104152367 KLC1 -0.55 -8.98 -0.44 1.86e-17 Reticulocyte count; LIHC cis rs13161895 0.941 rs12519642 chr5:179438626 T/G cg02702477 chr5:179499311 RNF130 -0.74 -10.27 -0.49 9.85e-22 LDL cholesterol; LIHC cis rs1577917 1.000 rs12201880 chr6:86627007 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.56 -0.5 9.5e-23 Response to antipsychotic treatment; LIHC cis rs801193 1.000 rs7782320 chr7:66177098 C/T cg18876405 chr7:65276391 NA 0.43 7.53 0.38 4.67e-13 Aortic root size; LIHC cis rs7100689 0.784 rs10749562 chr10:82108253 G/T cg00277334 chr10:82204260 NA -0.54 -6.7 -0.34 8.4e-11 Post bronchodilator FEV1; LIHC cis rs9399135 0.967 rs11755229 chr6:135369913 A/G cg24558204 chr6:135376177 HBS1L 0.42 6.81 0.35 4.49e-11 Red blood cell count; LIHC cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg05555928 chr11:63887634 MACROD1 0.55 7.47 0.37 6.77e-13 Mean platelet volume; LIHC cis rs2842992 0.747 rs9365095 chr6:160192928 T/G cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.24 0.55 7.91e-29 Age-related macular degeneration (geographic atrophy); LIHC cis rs853679 0.517 rs9357063 chr6:28060005 G/A cg16479474 chr6:28041457 NA 0.47 6.69 0.34 8.87e-11 Depression; LIHC cis rs7945705 0.776 rs11042069 chr11:8817315 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.36 5.87 0.3 1.06e-8 Hemoglobin concentration; LIHC cis rs6754311 0.731 rs3769005 chr2:136603366 C/G cg25344623 chr2:136566232 LCT 0.41 8.58 0.42 3.26e-16 Mosquito bite size; LIHC cis rs6089584 1.000 rs6089585 chr20:60564395 G/A cg12751644 chr20:60527061 NA -0.37 -6.09 -0.31 3.12e-9 Body mass index; LIHC cis rs17376456 0.825 rs13361613 chr5:93272176 C/T cg25358565 chr5:93447407 FAM172A 1.09 10.01 0.48 7.19e-21 Diabetic retinopathy; LIHC cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg25894440 chr7:65020034 NA -0.54 -6.13 -0.31 2.37e-9 Diabetic kidney disease; LIHC trans rs7395662 0.591 rs4882233 chr11:48739653 A/G cg15704280 chr7:45808275 SEPT13 -0.5 -7.64 -0.38 2.28e-13 HDL cholesterol; LIHC cis rs17102423 0.660 rs7152277 chr14:65535391 G/C cg16583315 chr14:65563665 MAX -0.35 -6.61 -0.34 1.46e-10 Obesity-related traits; LIHC cis rs911119 0.818 rs12625182 chr20:23604023 G/T cg16589663 chr20:23618590 CST3 0.76 8.04 0.4 1.44e-14 Chronic kidney disease; LIHC cis rs4474465 0.790 rs10793325 chr11:78252575 T/C cg27205649 chr11:78285834 NARS2 0.4 6.21 0.32 1.58e-9 Alzheimer's disease (survival time); LIHC cis rs933688 1.000 rs2052553 chr5:90729906 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.87 17.94 0.7 3.31e-51 Smoking behavior; LIHC cis rs6456156 0.586 rs12529876 chr6:167461501 G/A cg12798992 chr6:167411361 FGFR1OP 0.42 6.57 0.33 1.87e-10 Primary biliary cholangitis; LIHC cis rs7208859 0.623 rs55724095 chr17:29153058 A/G cg14067834 chr17:29058358 SUZ12P 0.69 6.76 0.34 5.89e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9381040 0.655 rs2268192 chr6:41024626 T/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.42 -0.33 4.67e-10 Alzheimer's disease (late onset); LIHC cis rs9649213 0.593 rs1859482 chr7:97983774 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.99 -0.31 5.24e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs2274273 0.624 rs11848575 chr14:55755788 A/G cg01864836 chr14:55583639 NA -0.36 -5.96 -0.31 6.43e-9 Protein biomarker; LIHC cis rs17253792 0.822 rs10137340 chr14:56050989 A/G cg01858014 chr14:56050164 KTN1 -0.75 -8.46 -0.42 7.94e-16 Putamen volume; LIHC cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg21448741 chr8:58168803 NA 0.35 6.5 0.33 2.9e-10 Developmental language disorder (linguistic errors); LIHC cis rs4589502 0.841 rs75991095 chr15:67123224 C/G cg09911534 chr15:67153556 NA -0.51 -6.17 -0.32 1.92e-9 Lung cancer (smoking interaction); LIHC cis rs12188164 0.525 rs2561665 chr5:460135 A/G cg26072250 chr5:443457 EXOC3;C5orf55 0.48 7.09 0.36 7.56e-12 Cystic fibrosis severity; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg25163015 chr11:64052221 BAD;GPR137 -0.42 -6.19 -0.32 1.68e-9 Triglycerides; LIHC cis rs9291683 0.588 rs35866697 chr4:10018604 C/A cg11266682 chr4:10021025 SLC2A9 0.33 7.14 0.36 5.57e-12 Bone mineral density; LIHC cis rs7584330 0.955 rs13432426 chr2:238388631 T/G cg14458575 chr2:238380390 NA 0.37 5.9 0.3 8.72e-9 Prostate cancer; LIHC cis rs933688 1.000 rs60513756 chr5:90727692 A/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 15.72 0.65 2.66e-42 Smoking behavior; LIHC cis rs7772486 0.875 rs9403768 chr6:146406458 A/C cg23711669 chr6:146136114 FBXO30 0.64 10.99 0.51 2.85e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2795502 1.000 rs2744090 chr10:43339614 G/C cg20628663 chr10:43360327 NA -0.46 -7.2 -0.36 3.87e-12 Blood protein levels; LIHC cis rs8141529 0.732 rs5762815 chr22:29205076 A/G cg15103426 chr22:29168792 CCDC117 0.66 11.36 0.52 1.32e-25 Lymphocyte counts; LIHC cis rs4699052 1.000 rs6533060 chr4:104139996 T/C cg16532752 chr4:104119610 CENPE -0.42 -6.76 -0.34 5.94e-11 Testicular germ cell tumor; LIHC trans rs1005277 0.579 rs2474595 chr10:38426782 C/G cg27523141 chr10:43048294 ZNF37B -0.36 -6.18 -0.32 1.86e-9 Extrinsic epigenetic age acceleration; LIHC cis rs17685 0.712 rs10275521 chr7:75770972 T/C cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.94e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs6502050 0.799 rs4789674 chr17:80123200 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs892961 0.932 rs7222170 chr17:75413096 G/A cg01320579 chr17:75405842 SEPT9 0.52 7.43 0.37 8.78e-13 Airflow obstruction; LIHC cis rs921968 0.613 rs2556388 chr2:219541056 T/C cg02985541 chr2:219472218 PLCD4 -0.39 -6.52 -0.33 2.58e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs7107174 1.000 rs2512546 chr11:77957276 T/C cg02023728 chr11:77925099 USP35 0.44 8.57 0.42 3.53e-16 Testicular germ cell tumor; LIHC cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg26338869 chr17:61819248 STRADA 0.52 6.97 0.35 1.62e-11 Height; LIHC cis rs7264396 0.836 rs6088880 chr20:34165582 G/C cg04508476 chr20:34239394 CPNE1;RBM12 0.41 6.99 0.35 1.43e-11 Total cholesterol levels; LIHC cis rs7572733 0.534 rs2060488 chr2:198751637 T/G cg10820045 chr2:198174542 NA 0.47 6.97 0.35 1.6e-11 Dermatomyositis; LIHC cis rs2760061 0.583 rs708118 chr1:228201801 A/G cg01200585 chr1:228362443 C1orf69 -0.46 -7.27 -0.37 2.46e-12 Diastolic blood pressure; LIHC cis rs155076 1.000 rs2478824 chr13:21844144 G/C cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.3e-30 White matter hyperintensity burden; LIHC cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.62 12.1 0.55 2.66e-28 Prudent dietary pattern; LIHC cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.34 0.45 1.3e-18 Bipolar disorder; LIHC cis rs28830936 0.966 rs2277535 chr15:42119711 G/A cg17847044 chr15:42102381 MAPKBP1 -0.31 -6.07 -0.31 3.48e-9 Diastolic blood pressure; LIHC cis rs6456156 0.565 rs7750209 chr6:167482895 T/G cg23791538 chr6:167370224 RNASET2 -0.54 -8.54 -0.42 4.58e-16 Primary biliary cholangitis; LIHC cis rs807029 0.577 rs3740488 chr10:102754033 A/T cg17130504 chr10:102756923 LZTS2 0.55 7.78 0.39 8.44e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs919433 0.647 rs13404366 chr2:198522632 A/G cg03934865 chr2:198174659 NA 0.44 6.58 0.34 1.77e-10 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg05564831 chr3:52568323 NT5DC2 0.37 6.08 0.31 3.25e-9 Bipolar disorder; LIHC cis rs3008870 0.755 rs2815360 chr1:67494458 C/T cg02640540 chr1:67518911 SLC35D1 0.43 6.8 0.35 4.68e-11 Lymphocyte percentage of white cells; LIHC cis rs7044106 0.791 rs4836830 chr9:123483668 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 8.27 0.41 3.03e-15 Hip circumference adjusted for BMI; LIHC cis rs3008870 1.000 rs2815371 chr1:67504313 A/G cg02640540 chr1:67518911 SLC35D1 0.46 6.25 0.32 1.19e-9 Lymphocyte percentage of white cells; LIHC cis rs80282103 0.571 rs56183119 chr10:1068370 C/T cg18964960 chr10:1102726 WDR37 0.66 6.39 0.33 5.36e-10 Glomerular filtration rate (creatinine); LIHC cis rs6952808 0.595 rs3778984 chr7:2166514 T/C cg02951883 chr7:2050386 MAD1L1 -0.65 -10.65 -0.5 4.66e-23 Bipolar disorder and schizophrenia; LIHC cis rs965469 0.779 rs6051780 chr20:3334167 A/C cg25506879 chr20:3388711 C20orf194 -0.54 -6.63 -0.34 1.3e-10 IFN-related cytopenia; LIHC cis rs12478296 0.792 rs6755390 chr2:243012998 C/T cg18898632 chr2:242989856 NA -0.57 -7.66 -0.38 1.91e-13 Obesity-related traits; LIHC cis rs11626933 0.589 rs10140761 chr14:90740588 G/C cg14092571 chr14:90743983 NA 0.57 9.39 0.45 8.51e-19 Gut microbiota (bacterial taxa); LIHC cis rs611744 0.560 rs58605513 chr8:109279122 A/C cg21045802 chr8:109455806 TTC35 0.6 10.49 0.49 1.6400000000000001e-22 Dupuytren's disease; LIHC cis rs72781680 0.611 rs55905755 chr2:24330264 T/C cg06627628 chr2:24431161 ITSN2 -0.65 -7.58 -0.38 3.21e-13 Lymphocyte counts; LIHC cis rs7107174 0.792 rs10899488 chr11:78088754 A/G cg02023728 chr11:77925099 USP35 0.48 8.74 0.43 1.05e-16 Testicular germ cell tumor; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg03051577 chr14:103366987 TRAF3 0.44 6.25 0.32 1.2e-9 Longevity; LIHC cis rs3770081 1.000 rs12621992 chr2:86345349 A/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.45 5.76 0.3 1.88e-8 Facial emotion recognition (sad faces); LIHC cis rs847649 0.692 rs7800548 chr7:102481842 C/T cg18108683 chr7:102477205 FBXL13 0.53 8.33 0.41 1.92e-15 Morning vs. evening chronotype; LIHC cis rs11758351 0.866 rs77205516 chr6:26205356 T/A cg11342453 chr6:26196699 NA 0.53 5.92 0.3 7.83e-9 Gout;Renal underexcretion gout; LIHC cis rs769267 0.930 rs4808203 chr19:19568659 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.47 6.58 0.34 1.81e-10 Tonsillectomy; LIHC cis rs2739330 0.791 rs9612520 chr22:24269459 G/T cg11060661 chr22:24314208 DDT;DDTL 0.68 11.85 0.54 2.23e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10791097 0.694 rs10791103 chr11:130757161 G/A cg12179176 chr11:130786555 SNX19 0.86 14.08 0.61 7.66e-36 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs240764 0.658 rs1336244 chr6:101197953 C/T cg12253828 chr6:101329408 ASCC3 -0.4 -6.07 -0.31 3.34e-9 Neuroticism; LIHC cis rs1419980 0.673 rs10772553 chr12:7768089 G/A cg14906510 chr12:7781169 NA -0.46 -7.12 -0.36 6.46e-12 HDL cholesterol levels; LIHC cis rs6424115 0.830 rs6680132 chr1:24198804 T/C cg10978503 chr1:24200527 CNR2 0.34 8.06 0.4 1.33e-14 Immature fraction of reticulocytes; LIHC cis rs11190604 1.000 rs2273695 chr10:102259568 A/G cg07080220 chr10:102295463 HIF1AN 0.49 6.97 0.35 1.65e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs17270561 0.779 rs1165200 chr6:25875212 C/T cg17691542 chr6:26056736 HIST1H1C -0.64 -7.42 -0.37 9.11e-13 Iron status biomarkers; LIHC cis rs11758351 1.000 rs77957229 chr6:26185226 A/G cg01420254 chr6:26195488 NA 0.54 5.81 0.3 1.44e-8 Gout;Renal underexcretion gout; LIHC cis rs6754311 0.608 rs3739020 chr2:136602491 T/G cg15123519 chr2:136567270 LCT -0.36 -7.05 -0.36 1.02e-11 Mosquito bite size; LIHC cis rs875971 0.895 rs10447522 chr7:65796074 A/G cg11764359 chr7:65958608 NA -0.77 -13.41 -0.59 3.06e-33 Aortic root size; LIHC cis rs13191362 1.000 rs13190742 chr6:163008758 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.72 0.3 2.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7100689 0.784 rs2153455 chr10:82139732 T/C cg00277334 chr10:82204260 NA -0.53 -6.76 -0.34 6.08e-11 Post bronchodilator FEV1; LIHC cis rs9596863 0.898 rs9568908 chr13:54336521 A/C ch.13.53330881F chr13:54432880 NA 0.45 6.21 0.32 1.5e-9 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC cis rs8180040 0.726 rs6774733 chr3:46991241 G/A cg27129171 chr3:47204927 SETD2 0.61 10.57 0.5 8.99e-23 Colorectal cancer; LIHC cis rs7116495 0.609 rs79889241 chr11:71815585 T/C cg10381502 chr11:71823885 C11orf51 1.08 9.2 0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg26818010 chr10:134567672 INPP5A -0.78 -9.34 -0.45 1.25e-18 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4906332 1.000 rs17680085 chr14:103953154 T/C cg19000871 chr14:103996768 TRMT61A -0.47 -7.93 -0.39 3.16e-14 Coronary artery disease; LIHC cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg19318889 chr4:1322082 MAEA 0.41 6.72 0.34 7.62e-11 Obesity-related traits; LIHC cis rs311392 0.867 rs434952 chr8:55091998 C/T cg11783602 chr8:55087084 NA -0.31 -6.2 -0.32 1.66e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg13047869 chr3:10149882 C3orf24 0.48 5.81 0.3 1.44e-8 Alzheimer's disease; LIHC cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg03264133 chr6:25882463 NA -0.63 -8.85 -0.43 4.88e-17 Blood metabolite levels; LIHC cis rs7408868 1.000 rs7249525 chr19:15277309 G/A cg09752223 chr19:15281200 NOTCH3 -0.37 -5.83 -0.3 1.28e-8 Pulse pressure; LIHC cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg12379764 chr21:47803548 PCNT -0.62 -9.21 -0.45 3.35e-18 Testicular germ cell tumor; LIHC cis rs9420 0.961 rs2847308 chr11:57498232 C/T cg19752551 chr11:57585705 CTNND1 0.51 7.25 0.37 2.72e-12 Schizophrenia; LIHC cis rs7617773 0.925 rs6442105 chr3:48182326 A/G cg11946769 chr3:48343235 NME6 -0.62 -7.83 -0.39 6.38e-14 Coronary artery disease; LIHC cis rs3812831 0.599 rs428636 chr13:114927133 T/C cg06611532 chr13:114900021 NA 0.42 7.49 0.38 5.83e-13 Schizophrenia; LIHC cis rs3540 0.597 rs11639150 chr15:91042071 C/G cg22089800 chr15:90895588 ZNF774 -0.59 -8.08 -0.4 1.16e-14 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs1568889 1.000 rs33937991 chr11:28045260 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.5 6.93 0.35 2.04e-11 Bipolar disorder; LIHC cis rs3820068 0.603 rs16851884 chr1:15961871 A/G cg17385448 chr1:15911702 AGMAT 0.33 5.8 0.3 1.53e-8 Systolic blood pressure; LIHC cis rs1062177 1.000 rs17741826 chr5:151149262 C/T cg00977110 chr5:151150581 G3BP1 -0.56 -7.03 -0.36 1.11e-11 Preschool internalizing problems; LIHC cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg21448741 chr8:58168803 NA 0.32 5.82 0.3 1.36e-8 Developmental language disorder (linguistic errors); LIHC cis rs6546550 0.901 rs11902198 chr2:70144596 C/A cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC cis rs6750047 0.587 rs2163454 chr2:38279170 A/C cg07380506 chr2:38303506 CYP1B1 0.59 7.5 0.38 5.59e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs60871478 1.000 rs4397290 chr7:828493 T/C cg04727924 chr7:799746 HEATR2 0.58 8.73 0.43 1.17e-16 Cerebrospinal P-tau181p levels; LIHC cis rs11148252 0.774 rs9596649 chr13:52934610 A/G cg00495681 chr13:53174319 NA -0.4 -6.67 -0.34 1e-10 Lewy body disease; LIHC cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg21280719 chr6:42927975 GNMT -0.35 -7.89 -0.39 4.25e-14 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1538970 0.781 rs12049503 chr1:46021556 G/T cg05343316 chr1:45956843 TESK2 0.54 7.36 0.37 1.42e-12 Platelet count; LIHC cis rs951366 0.789 rs823152 chr1:205736285 G/A cg24503407 chr1:205819492 PM20D1 0.76 10.9 0.51 5.85e-24 Menarche (age at onset); LIHC cis rs933688 1.000 rs12656350 chr5:90751343 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.88 15.73 0.65 2.38e-42 Smoking behavior; LIHC cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg02475777 chr4:1388615 CRIPAK 0.53 7.67 0.38 1.85e-13 Longevity; LIHC cis rs11792861 0.926 rs7856626 chr9:111775502 C/G cg05043794 chr9:111880884 C9orf5 -0.3 -6.97 -0.35 1.6e-11 Menarche (age at onset); LIHC cis rs10779751 0.734 rs2748877 chr1:11129437 T/C cg08854313 chr1:11322531 MTOR 0.67 10.21 0.48 1.56e-21 Body mass index; LIHC cis rs8044995 0.636 rs117761434 chr16:68254196 G/A cg05110241 chr16:68378359 PRMT7 -0.61 -6.77 -0.34 5.71e-11 Schizophrenia; LIHC cis rs59901009 0.911 rs10500722 chr11:10235358 T/G cg01453529 chr11:10209919 SBF2 0.31 6.08 0.31 3.29e-9 Hematocrit;Hemoglobin concentration; LIHC cis rs40363 0.523 rs757270 chr16:3534451 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.46 6.53 0.33 2.41e-10 Tuberculosis; LIHC cis rs7172677 0.501 rs56266638 chr15:75393205 T/A cg15902774 chr15:75289873 SCAMP5 0.34 5.96 0.31 6.21e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC trans rs2727020 0.619 rs1164665 chr11:49295630 T/C cg18944383 chr4:111397179 ENPEP -0.31 -6.98 -0.35 1.57e-11 Coronary artery disease; LIHC cis rs2842992 0.789 rs2342446 chr6:160220687 A/G cg11366901 chr6:160182831 ACAT2 0.93 15.41 0.64 4.56e-41 Age-related macular degeneration (geographic atrophy); LIHC cis rs7116495 1.000 rs10736781 chr11:71650368 T/C cg26138937 chr11:71823887 C11orf51 -0.67 -6.83 -0.35 3.88e-11 Severe influenza A (H1N1) infection; LIHC cis rs3762637 0.943 rs9872708 chr3:122242807 C/G cg24169773 chr3:122142474 KPNA1 -0.44 -8.84 -0.43 5.15e-17 LDL cholesterol levels; LIHC cis rs2439831 1.000 rs2256764 chr15:43735763 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 11.82 0.54 3e-27 Lung cancer in ever smokers; LIHC cis rs6785206 0.803 rs2712380 chr3:128338661 A/C cg16766828 chr3:128327626 NA -0.62 -6.91 -0.35 2.38e-11 Lymphocyte percentage of white cells; LIHC trans rs12310956 0.532 rs11052954 chr12:33993512 C/G cg26384229 chr12:38710491 ALG10B 0.46 6.4 0.33 5.12e-10 Morning vs. evening chronotype; LIHC cis rs17152411 1.000 rs733402 chr10:126594152 T/C cg07906193 chr10:126599966 NA 0.46 7.15 0.36 5.33e-12 Height; LIHC cis rs34375054 0.553 rs12581512 chr12:125622262 G/A cg25124228 chr12:125621409 AACS -0.55 -10.23 -0.48 1.31e-21 Post bronchodilator FEV1/FVC ratio; LIHC cis rs1443512 0.812 rs4759058 chr12:54339052 C/A cg25024717 chr12:54324583 NA -0.31 -6.19 -0.32 1.73e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg10755058 chr3:40428713 ENTPD3 0.41 7.06 0.36 9.37e-12 Renal cell carcinoma; LIHC cis rs7945705 0.747 rs2568020 chr11:8994715 C/T cg12365402 chr11:9010492 NRIP3 -0.33 -8.76 -0.43 8.93e-17 Hemoglobin concentration; LIHC cis rs6951245 0.638 rs4720486 chr7:1146764 G/A cg04025307 chr7:1156635 C7orf50 0.63 6.32 0.32 8.18e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs7618501 0.519 rs3774749 chr3:50207227 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.53 -7.77 -0.39 9.24e-14 Intelligence (multi-trait analysis); LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs2153535 0.967 rs10484750 chr6:8378609 A/G cg07606381 chr6:8435919 SLC35B3 -0.41 -5.84 -0.3 1.21e-8 Motion sickness; LIHC cis rs10876993 0.890 rs7963927 chr12:58046272 T/G cg04478727 chr12:58166393 METTL1;FAM119B -0.46 -6.52 -0.33 2.54e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs7131987 0.509 rs11050173 chr12:29441473 T/A cg14222432 chr12:29376421 FAR2 0.35 6.23 0.32 1.37e-9 QT interval; LIHC cis rs17376456 0.569 rs1349711 chr5:93179032 C/T cg25358565 chr5:93447407 FAM172A -0.79 -7.67 -0.38 1.75e-13 Diabetic retinopathy; LIHC cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg18357526 chr6:26021779 HIST1H4A 1.03 14.69 0.62 3.32e-38 Intelligence (multi-trait analysis); LIHC trans rs6598955 0.627 rs6684875 chr1:26567044 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.81 -9.1 -0.44 7.57e-18 Obesity-related traits; LIHC cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.45 6.39 0.33 5.49e-10 Bipolar disorder; LIHC cis rs1005277 0.579 rs2474599 chr10:38438939 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2292096 0.866 rs34674691 chr1:200696645 C/T cg11814564 chr1:200748674 CAMSAP1L1 -0.45 -6.03 -0.31 4.24e-9 Epilepsy; LIHC cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg27211696 chr2:191398769 TMEM194B -0.64 -10.52 -0.49 1.31e-22 Pulse pressure; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12145289 chr11:65385911 PCNXL3 0.39 6.19 0.32 1.69e-9 Longevity; LIHC cis rs7927771 0.524 rs61895760 chr11:47794538 G/C cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs9682041 0.561 rs1477211 chr3:170140792 A/G cg11886554 chr3:170076028 SKIL 0.76 5.85 0.3 1.18e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg21448741 chr8:58168803 NA 0.37 6.76 0.34 5.8200000000000003e-11 Developmental language disorder (linguistic errors); LIHC cis rs17685 0.725 rs7807647 chr7:75628669 G/A cg04610667 chr7:75704037 NA 0.33 5.94 0.31 6.91e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs288342 0.763 rs288239 chr2:183645816 C/G cg02625481 chr2:183667124 NA -0.29 -6.04 -0.31 3.95e-9 Recurrent major depressive disorder; LIHC cis rs344364 0.511 rs1742463 chr16:1946110 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.44 -0.37 8.31e-13 Glomerular filtration rate in chronic kidney disease; LIHC cis rs7520050 0.933 rs6680211 chr1:46315007 C/G cg03146154 chr1:46216737 IPP -0.37 -5.92 -0.3 8e-9 Red blood cell count;Reticulocyte count; LIHC cis rs66887589 0.807 rs7694483 chr4:120405929 T/A cg09307838 chr4:120376055 NA 0.48 7.48 0.37 6.38e-13 Diastolic blood pressure; LIHC cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg18306943 chr3:40428807 ENTPD3 0.36 6.31 0.32 8.81e-10 Renal cell carcinoma; LIHC cis rs72781680 0.821 rs72790304 chr2:24108557 G/A cg08917208 chr2:24149416 ATAD2B 0.67 6.6 0.34 1.56e-10 Lymphocyte counts; LIHC cis rs2404602 0.716 rs17363713 chr15:76746128 G/C cg23625390 chr15:77176239 SCAPER 0.37 6.1 0.31 2.79e-9 Blood metabolite levels; LIHC cis rs6066825 0.568 rs6095245 chr20:47320770 G/C cg18078177 chr20:47281410 PREX1 0.43 7.07 0.36 8.84e-12 Colorectal cancer; LIHC cis rs2832191 0.692 rs8134627 chr21:30349069 C/T cg08807101 chr21:30365312 RNF160 -0.79 -12.0 -0.54 6.33e-28 Dental caries; LIHC cis rs7100689 0.646 rs2050824 chr10:82123563 G/A cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs1552244 0.832 rs3732968 chr3:10013273 A/G cg08888203 chr3:10149979 C3orf24 0.49 6.13 0.31 2.4e-9 Alzheimer's disease; LIHC cis rs2153535 0.542 rs9505465 chr6:8510846 C/T cg21535247 chr6:8435926 SLC35B3 0.61 7.97 0.4 2.34e-14 Motion sickness; LIHC cis rs2346177 0.554 rs13002880 chr2:46708129 C/G cg02822958 chr2:46747628 ATP6V1E2 0.52 7.86 0.39 5.11e-14 HDL cholesterol; LIHC cis rs908922 0.676 rs498184 chr1:152501423 G/C cg20991723 chr1:152506922 NA 0.5 8.46 0.42 7.65e-16 Hair morphology; LIHC cis rs8078723 0.510 rs11655264 chr17:38138995 G/C cg17467752 chr17:38218738 THRA -0.56 -9.62 -0.46 1.5700000000000001e-19 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg08067268 chr2:26466485 HADHB;HADHA 0.45 6.81 0.35 4.4e-11 Gut microbiome composition (summer); LIHC cis rs2576037 0.583 rs1465722 chr18:44564499 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.73 -11.59 -0.53 2.02e-26 Personality dimensions; LIHC cis rs4478037 0.749 rs6550204 chr3:33107645 C/T cg16652328 chr3:33138982 GLB1;TMPPE 0.6 7.81 0.39 7.13e-14 Major depressive disorder; LIHC cis rs611744 0.506 rs4735054 chr8:109261780 A/C cg18478394 chr8:109455254 TTC35 -0.36 -6.12 -0.31 2.63e-9 Dupuytren's disease; LIHC cis rs6088590 1.000 rs55753039 chr20:33394940 C/T cg08999081 chr20:33150536 PIGU 0.39 5.77 0.3 1.75e-8 Coronary artery disease; LIHC cis rs4689642 0.709 rs4689657 chr4:7225818 G/C cg21353189 chr4:7228343 SORCS2 0.37 6.39 0.33 5.58e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs6840360 0.869 rs55668815 chr4:152473828 C/G cg22705602 chr4:152727874 NA -0.28 -5.98 -0.31 5.49e-9 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg21724239 chr8:58056113 NA 0.57 7.26 0.37 2.63e-12 Developmental language disorder (linguistic errors); LIHC cis rs11711311 0.911 rs28577577 chr3:113447276 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.39 -7.06 -0.36 9.32e-12 IgG glycosylation; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03621406 chr19:9930365 FBXL12 -0.39 -6.46 -0.33 3.68e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg06238570 chr21:40685208 BRWD1 0.6 7.19 0.36 4.1e-12 Cognitive function; LIHC cis rs2303759 0.709 rs2278405 chr19:49812403 A/C cg05022225 chr19:49866942 DKKL1;TEAD2 -0.52 -7.53 -0.38 4.52e-13 Multiple sclerosis; LIHC cis rs13108904 0.518 rs4974603 chr4:1343168 C/T cg00684032 chr4:1343700 KIAA1530 0.58 8.34 0.41 1.89e-15 Obesity-related traits; LIHC cis rs7927771 0.864 rs60075622 chr11:47449101 T/G cg20307385 chr11:47447363 PSMC3 -0.49 -6.33 -0.32 7.48e-10 Subjective well-being; LIHC cis rs1949733 0.877 rs940133 chr4:8473614 T/C cg11789530 chr4:8429930 ACOX3 0.71 9.52 0.46 3.29e-19 Response to antineoplastic agents; LIHC cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg05896524 chr21:47604654 C21orf56 0.51 8.25 0.41 3.55e-15 Testicular germ cell tumor; LIHC cis rs75064307 0.834 rs10511271 chr3:108114572 A/G cg03329597 chr3:108125523 MYH15 -0.5 -6.62 -0.34 1.36e-10 Intelligence (multi-trait analysis); LIHC cis rs2274273 0.967 rs67756714 chr14:55589823 G/A cg01864836 chr14:55583639 NA -0.36 -6.1 -0.31 2.94e-9 Protein biomarker; LIHC cis rs9549367 0.789 rs2287244 chr13:113887173 C/G cg00898013 chr13:113819073 PROZ 0.35 6.4 0.33 5.09e-10 Platelet distribution width; LIHC cis rs11098499 0.954 rs11098526 chr4:120390359 C/T cg09307838 chr4:120376055 NA 0.76 12.0 0.54 6.33e-28 Corneal astigmatism; LIHC cis rs208520 0.690 rs12208977 chr6:66725257 G/A cg07460842 chr6:66804631 NA 0.78 9.03 0.44 1.31e-17 Exhaled nitric oxide output; LIHC cis rs1801251 0.963 rs13011298 chr2:233612996 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.13 0.52 9.15e-25 Coronary artery disease; LIHC cis rs6582630 0.537 rs1949611 chr12:38373092 C/T cg26384229 chr12:38710491 ALG10B -0.58 -8.22 -0.41 4.29e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg04944784 chr2:26401820 FAM59B -0.72 -9.21 -0.45 3.36e-18 Gut microbiome composition (summer); LIHC trans rs1005277 0.505 rs7099777 chr10:38183569 A/C cg27523141 chr10:43048294 ZNF37B -0.39 -6.88 -0.35 2.8e-11 Extrinsic epigenetic age acceleration; LIHC cis rs11030122 0.702 rs1452047 chr11:3991648 A/C cg18678763 chr11:4115507 RRM1 -0.57 -8.33 -0.41 2.03e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs9296092 0.521 rs6929165 chr6:33515958 T/G cg13560919 chr6:33536144 NA -0.39 -6.85 -0.35 3.52e-11 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7666738 0.830 rs28497822 chr4:98906873 C/T cg05340658 chr4:99064831 C4orf37 0.65 11.92 0.54 1.29e-27 Colonoscopy-negative controls vs population controls; LIHC trans rs916888 0.821 rs199514 chr17:44856881 G/A cg26692224 chr17:62915920 LRRC37A3 0.66 6.36 0.33 6.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs801193 1.000 rs2707850 chr7:66203870 G/T cg00343986 chr7:65444356 GUSB 0.41 6.12 0.31 2.5e-9 Aortic root size; LIHC trans rs2243480 1.000 rs13235972 chr7:65883605 C/T cg10756647 chr7:56101905 PSPH 1.02 12.41 0.56 1.81e-29 Diabetic kidney disease; LIHC cis rs611744 0.647 rs674391 chr8:109242803 A/T cg21045802 chr8:109455806 TTC35 0.57 10.31 0.49 7.21e-22 Dupuytren's disease; LIHC cis rs2075371 1.000 rs1868783 chr7:133975087 A/G cg11752832 chr7:134001865 SLC35B4 0.48 7.36 0.37 1.34e-12 Mean platelet volume; LIHC cis rs7772486 0.686 rs4896833 chr6:145965673 T/G cg23711669 chr6:146136114 FBXO30 0.64 11.62 0.53 1.55e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9790314 0.875 rs336580 chr3:161082982 A/T cg03342759 chr3:160939853 NMD3 -0.67 -9.14 -0.44 5.61e-18 Morning vs. evening chronotype; LIHC cis rs921968 0.643 rs659185 chr2:219335935 C/T cg17980119 chr2:219472607 PLCD4 0.36 6.19 0.32 1.68e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs372883 0.600 rs1312254 chr21:30695401 A/G cg08807101 chr21:30365312 RNF160 -0.51 -5.86 -0.3 1.07e-8 Pancreatic cancer; LIHC cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg10360323 chr17:41437877 NA 0.4 5.94 0.31 7.1e-9 Menopause (age at onset); LIHC cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg16405210 chr4:1374714 KIAA1530 -0.46 -7.0 -0.35 1.36e-11 Obesity-related traits; LIHC cis rs600626 0.529 rs2004638 chr11:75471012 C/T cg24262691 chr11:75473276 NA 0.44 6.5 0.33 2.8e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs7772486 0.597 rs2485631 chr6:146190077 G/C cg05347473 chr6:146136440 FBXO30 0.47 7.0 0.35 1.32e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs17401966 0.931 rs912961 chr1:10356848 A/G cg19773385 chr1:10388646 KIF1B -0.41 -7.25 -0.37 2.76e-12 Hepatocellular carcinoma; LIHC cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg20818283 chr2:191399100 TMEM194B 0.46 5.99 0.31 5.36e-9 Pulse pressure; LIHC cis rs910316 0.687 rs11627442 chr14:75669649 A/G cg08847533 chr14:75593920 NEK9 -0.79 -15.02 -0.63 1.63e-39 Height; LIHC cis rs1707322 0.752 rs28812624 chr1:46203736 T/A cg06784218 chr1:46089804 CCDC17 0.41 7.22 0.36 3.46e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg05527609 chr1:210001259 C1orf107 0.43 6.37 0.33 6.08e-10 Cleft lip with or without cleft palate; LIHC cis rs3007729 0.509 rs6665151 chr1:18800247 A/G cg04846421 chr1:18800208 NA -0.48 -7.94 -0.39 2.88e-14 Diabetic retinopathy; LIHC trans rs7618501 0.571 rs2240329 chr3:50107512 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.57 -9.34 -0.45 1.3e-18 Intelligence (multi-trait analysis); LIHC trans rs7618501 0.699 rs2681780 chr3:49897830 C/T cg21659725 chr3:3221576 CRBN 0.74 11.57 0.53 2.4e-26 Intelligence (multi-trait analysis); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg04381043 chr16:89341467 ANKRD11 0.42 6.17 0.32 1.9e-9 Bilirubin levels; LIHC cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.14 0.32 2.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10053149 chr1:28908509 SNHG12;SNORA44;SNORA16A 0.5 6.35 0.32 6.87e-10 Lung function (FEV1/FVC); LIHC cis rs4474465 0.833 rs7934912 chr11:78218556 A/T cg27205649 chr11:78285834 NARS2 0.39 5.99 0.31 5.41e-9 Alzheimer's disease (survival time); LIHC cis rs7781266 0.500 rs2971975 chr7:133645355 G/A cg03336402 chr7:133662267 EXOC4 -0.47 -5.74 -0.3 2.14e-8 Educational attainment (college completion); LIHC cis rs2228479 0.850 rs17233664 chr16:89810628 C/T cg00800038 chr16:89945340 TCF25 -0.61 -8.89 -0.43 3.56e-17 Skin colour saturation; LIHC cis rs1801251 1.000 rs12474040 chr2:233615345 T/G cg08000102 chr2:233561755 GIGYF2 0.76 11.4 0.52 9.72e-26 Coronary artery disease; LIHC cis rs6088590 0.610 rs6088461 chr20:32905161 G/T cg06115741 chr20:33292138 TP53INP2 0.56 7.22 0.36 3.31e-12 Coronary artery disease; LIHC cis rs2016586 0.931 rs4821435 chr22:36113039 T/C cg26342177 chr22:36113512 APOL5 -0.38 -6.3 -0.32 9.32e-10 Body mass index; LIHC cis rs12497850 0.931 rs11705888 chr3:48817289 T/C cg06212747 chr3:49208901 KLHDC8B 0.57 7.42 0.37 9.22e-13 Parkinson's disease; LIHC cis rs6598955 0.670 rs10902734 chr1:26617923 G/T cg04990556 chr1:26633338 UBXN11 0.62 10.02 0.48 6.72e-21 Obesity-related traits; LIHC cis rs5769765 0.954 rs5770739 chr22:50268014 C/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs9527 1.000 rs12416687 chr10:104629011 T/C cg15744005 chr10:104629667 AS3MT -0.39 -6.46 -0.33 3.59e-10 Arsenic metabolism; LIHC cis rs4642101 0.662 rs3901664 chr3:12824660 T/C cg24848339 chr3:12840334 CAND2 0.33 6.9 0.35 2.51e-11 QRS complex (12-leadsum); LIHC cis rs8027181 0.839 rs998021 chr15:72999825 T/C cg03441853 chr15:73075003 ADPGK 0.28 5.8 0.3 1.5e-8 Triglyceride levels; LIHC trans rs116095464 0.558 rs2288458 chr5:231260 C/T cg00938859 chr5:1591904 SDHAP3 0.57 7.04 0.36 1.03e-11 Breast cancer; LIHC cis rs4660306 0.677 rs1691216 chr1:45899416 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC 0.64 6.49 0.33 3.05e-10 Homocysteine levels; LIHC cis rs7927771 0.965 rs3817335 chr11:47643891 T/A cg18512352 chr11:47633146 NA -0.25 -5.89 -0.3 9.23e-9 Subjective well-being; LIHC cis rs7953249 0.656 rs2178463 chr12:121389721 A/G cg02403541 chr12:121454288 C12orf43 -0.42 -7.29 -0.37 2.15e-12 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; LIHC cis rs7208859 0.623 rs9893422 chr17:29111715 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs752092 1.000 rs11636578 chr15:101787969 T/C cg19997662 chr15:101784653 CHSY1 -0.49 -6.16 -0.32 2.09e-9 Corneal structure; LIHC cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg15691649 chr6:25882328 NA 0.49 6.81 0.35 4.49e-11 Blood metabolite levels; LIHC cis rs7618501 1.000 rs1491986 chr3:49739086 C/T cg21467203 chr3:49911342 NA 0.4 6.95 0.35 1.81e-11 Intelligence (multi-trait analysis); LIHC cis rs11792861 0.926 rs72607163 chr9:111803128 G/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.37 0.41 1.48e-15 Menarche (age at onset); LIHC cis rs7918232 0.556 rs788209 chr10:27434716 G/T cg14240646 chr10:27532245 ACBD5 -0.83 -6.87 -0.35 3.07e-11 Breast cancer; LIHC cis rs7772486 0.597 rs6912351 chr6:146264071 T/C cg13319975 chr6:146136371 FBXO30 0.59 9.05 0.44 1.12e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs17345786 0.906 rs72940399 chr3:101122575 A/T cg12386194 chr3:101231763 SENP7 0.58 7.67 0.38 1.8e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg00149659 chr3:10157352 C3orf10 0.69 7.29 0.37 2.18e-12 Alzheimer's disease; LIHC cis rs6964587 1.000 rs6950470 chr7:91680641 G/A cg17063962 chr7:91808500 NA 1.03 20.83 0.75 8.51e-63 Breast cancer; LIHC cis rs798554 1.000 rs798560 chr7:2758309 A/G cg13628971 chr7:2884303 GNA12 0.5 7.22 0.36 3.31e-12 Height; LIHC cis rs12908161 1.000 rs35726233 chr15:85337800 C/T cg12863693 chr15:85201151 NMB 0.44 6.34 0.32 7.18e-10 Schizophrenia; LIHC cis rs9399137 0.507 rs13214669 chr6:135299959 T/C cg24558204 chr6:135376177 HBS1L 0.62 10.66 0.5 4.37e-23 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs2710642 0.586 rs12713462 chr2:62804482 C/T cg17519650 chr2:63277830 OTX1 0.39 6.1 0.31 2.93e-9 LDL cholesterol levels;LDL cholesterol; LIHC cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg12311636 chr6:118886798 C6orf204 -0.53 -6.22 -0.32 1.44e-9 Diastolic blood pressure; LIHC cis rs769267 0.965 rs2965188 chr19:19522557 G/A cg15052019 chr19:19431593 KIAA0892;SF4 0.43 6.01 0.31 4.78e-9 Tonsillectomy; LIHC cis rs875971 0.830 rs6976714 chr7:65891461 G/A cg18252515 chr7:66147081 NA -0.41 -5.8 -0.3 1.47e-8 Aortic root size; LIHC cis rs74181299 0.684 rs1228 chr2:65311555 C/T cg05010058 chr2:65284262 CEP68 -0.39 -6.51 -0.33 2.72e-10 Pulse pressure; LIHC cis rs2066819 1.000 rs11171803 chr12:56718422 T/C cg26734620 chr12:56694298 CS 1.3 11.14 0.52 8.3e-25 Psoriasis vulgaris; LIHC cis rs9818758 0.607 rs9990153 chr3:49291883 C/T cg00383909 chr3:49044727 WDR6 0.74 6.51 0.33 2.66e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs3768617 0.510 rs10797838 chr1:183077020 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 11.29 0.52 2.43e-25 Fuchs's corneal dystrophy; LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg04234412 chr22:24373322 LOC391322 0.94 16.1 0.66 8.45e-44 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2289583 0.642 rs55798479 chr15:75392210 C/T cg15902774 chr15:75289873 SCAMP5 0.34 5.82 0.3 1.35e-8 Systemic lupus erythematosus; LIHC cis rs4888262 0.508 rs7193583 chr16:74649589 C/G cg01733217 chr16:74700730 RFWD3 0.86 16.84 0.67 9.26e-47 Testicular germ cell tumor; LIHC cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg00166722 chr3:10149974 C3orf24 0.51 5.88 0.3 9.93e-9 Alzheimer's disease; LIHC cis rs5753618 0.561 rs9609254 chr22:31705942 G/A cg22777020 chr22:31556080 RNF185 0.55 6.35 0.32 6.77e-10 Colorectal cancer; LIHC cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg05527609 chr1:210001259 C1orf107 0.42 6.2 0.32 1.62e-9 Cleft lip with or without cleft palate; LIHC cis rs7772486 0.790 rs7753696 chr6:146279098 G/T cg13319975 chr6:146136371 FBXO30 0.38 6.03 0.31 4.21e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.742 rs12753439 chr1:110015519 G/A cg02415029 chr1:110025642 ATXN7L2 -0.43 -5.79 -0.3 1.56e-8 Intelligence (multi-trait analysis); LIHC cis rs999943 0.846 rs9348923 chr6:33617924 C/T cg14003231 chr6:33640908 ITPR3 0.37 7.76 0.39 1.02e-13 Obesity (extreme); LIHC cis rs2236918 0.932 rs1776131 chr1:242024245 T/A cg17736920 chr1:242011382 EXO1 0.58 8.5 0.42 5.82e-16 Menopause (age at onset); LIHC cis rs782590 0.764 rs2586970 chr2:55829967 A/G cg18811423 chr2:55921094 PNPT1 0.79 11.65 0.53 1.22e-26 Metabolic syndrome; LIHC cis rs4141404 0.851 rs5749248 chr22:31683711 C/A cg07713946 chr22:31675144 LIMK2 -0.45 -6.88 -0.35 2.79e-11 Paclitaxel-induced neuropathy; LIHC cis rs11997175 0.520 rs6994803 chr8:33817796 A/G ch.8.33884649F chr8:33765107 NA 0.38 6.27 0.32 1.07e-9 Body mass index; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26329020 chr12:32909488 YARS2 0.43 6.5 0.33 2.9e-10 Cognitive function; LIHC cis rs5769765 0.908 rs9616211 chr22:50317676 G/A cg02269571 chr22:50332266 NA -0.66 -9.04 -0.44 1.15e-17 Schizophrenia; LIHC cis rs600806 0.888 rs592107 chr1:109848726 A/T cg16275483 chr1:110013120 SYPL2 -0.5 -6.1 -0.31 2.87e-9 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs2572263 chr1:231509408 C/T cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs7772486 0.790 rs1062067 chr6:146207563 A/G cg05347473 chr6:146136440 FBXO30 0.37 5.94 0.31 7.11e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs8180040 0.903 rs6791842 chr3:47279810 T/C cg16586182 chr3:47516702 SCAP -0.53 -9.67 -0.46 1.02e-19 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16377939 chr16:53088918 CHD9 -0.46 -6.04 -0.31 4.12e-9 Pancreatic cancer; LIHC trans rs2665103 0.715 rs7403041 chr15:82580182 A/C cg18393722 chr15:85113863 UBE2QP1 0.46 7.4 0.37 1.1e-12 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.933 rs8074028 chr17:28461687 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.13 0.44 6.08e-18 Coffee consumption (cups per day); LIHC cis rs7075426 0.669 rs3758520 chr10:88233628 C/G cg07322936 chr10:88137208 NA 0.48 6.29 0.32 9.59e-10 Migraine without aura; LIHC cis rs10847980 0.590 rs1979237 chr12:123325895 C/T cg25930673 chr12:123319894 HIP1R 1.13 12.86 0.57 3.89e-31 Adiponectin levels; LIHC cis rs7828089 0.744 rs10108011 chr8:22320806 C/T cg12081754 chr8:22256438 SLC39A14 0.5 8.19 0.4 5.22e-15 Verbal declarative memory; LIHC cis rs9818758 0.545 rs9853352 chr3:49813258 C/T cg00383909 chr3:49044727 WDR6 -0.8 -5.99 -0.31 5.41e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs1055129 0.681 rs7221792 chr17:73834690 T/G cg10935138 chr17:73851978 WBP2 0.44 6.94 0.35 1.97e-11 White matter hyperintensity burden; LIHC cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg23782820 chr8:58130467 NA 0.34 5.93 0.31 7.46e-9 Developmental language disorder (linguistic errors); LIHC cis rs6088580 0.634 rs6120642 chr20:33012531 A/G cg08999081 chr20:33150536 PIGU 0.67 13.33 0.58 6.09e-33 Glomerular filtration rate (creatinine); LIHC cis rs7927592 0.913 rs55883802 chr11:68278829 G/A cg01657329 chr11:68192670 LRP5 -0.46 -6.02 -0.31 4.6e-9 Total body bone mineral density; LIHC cis rs760762 0.636 rs6072329 chr20:39915515 A/G cg06424997 chr20:39929561 ZHX3 -0.36 -5.96 -0.31 6.38e-9 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; LIHC cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg06873352 chr17:61820015 STRADA 0.5 7.44 0.37 8.07e-13 Height; LIHC cis rs11168351 0.926 rs10875719 chr12:48411158 T/C cg21466736 chr12:48725269 NA -0.59 -8.31 -0.41 2.2e-15 Bipolar disorder and schizophrenia; LIHC cis rs2073300 1.000 rs6114101 chr20:23446322 C/T cg12062639 chr20:23401060 NAPB 0.84 9.99 0.48 8.99e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9457247 0.663 rs12526548 chr6:167431147 C/T cg12798992 chr6:167411361 FGFR1OP 0.45 7.1 0.36 7.31e-12 Crohn's disease; LIHC cis rs1018836 0.663 rs2205151 chr8:91483468 A/C cg16814680 chr8:91681699 NA -0.46 -7.43 -0.37 8.72e-13 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs208515 0.525 rs10944870 chr6:66687757 G/C cg07460842 chr6:66804631 NA 0.79 8.97 0.44 1.94e-17 Exhaled nitric oxide levels; LIHC cis rs365132 0.967 rs11740768 chr5:176339499 G/A cg16309518 chr5:176445507 NA -0.58 -11.32 -0.52 1.87e-25 Menarche and menopause (age at onset);Menopause (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04315863 chr15:34330588 AVEN;CHRM5 0.44 6.09 0.31 3.07e-9 Pancreatic cancer; LIHC cis rs1552244 0.572 rs3774208 chr3:10164722 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.03 0.4 1.6e-14 Alzheimer's disease; LIHC cis rs12824058 0.831 rs12300308 chr12:130813825 G/A cg24229701 chr12:130821962 PIWIL1 0.44 6.8 0.35 4.54e-11 Menopause (age at onset); LIHC cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg18252515 chr7:66147081 NA -1.24 -16.44 -0.66 3.79e-45 Diabetic kidney disease; LIHC trans rs2262909 0.925 rs73019838 chr19:22247732 T/A cg17074339 chr11:11642133 GALNTL4 0.4 6.09 0.31 3.09e-9 Chagas cardiomyopathy in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs11098499 0.863 rs3822194 chr4:120471648 A/G cg09307838 chr4:120376055 NA 0.75 11.49 0.53 4.69e-26 Corneal astigmatism; LIHC cis rs35146811 0.844 rs12705070 chr7:99656927 A/G cg22906224 chr7:99728672 NA 0.41 5.91 0.3 8.48e-9 Coronary artery disease; LIHC cis rs4975709 0.838 rs4975753 chr5:1880865 T/C cg15595755 chr5:1867978 NA 0.34 6.42 0.33 4.53e-10 Cardiovascular disease risk factors; LIHC trans rs79976124 0.797 rs79522358 chr6:66641140 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.8 0.35 4.68e-11 Type 2 diabetes; LIHC cis rs12477438 0.765 rs7605734 chr2:99644068 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.67 -0.38 1.86e-13 Chronic sinus infection; LIHC cis rs11931598 0.782 rs4689581 chr4:7048134 C/T cg02503808 chr4:7069936 GRPEL1 -0.4 -6.0 -0.31 5.17e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs7429990 0.803 rs11714518 chr3:48156635 T/C cg11946769 chr3:48343235 NME6 -0.48 -6.41 -0.33 4.85e-10 Educational attainment (years of education); LIHC cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg06558623 chr16:89946397 TCF25 0.95 14.31 0.61 9.78e-37 Skin colour saturation; LIHC cis rs7208859 0.623 rs80355557 chr17:29154421 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.76 0.34 5.89e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg22528358 chr1:107598549 PRMT6 -0.69 -11.47 -0.53 5.69e-26 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs7572733 0.534 rs771009 chr2:198691082 A/G cg00792783 chr2:198669748 PLCL1 0.46 6.85 0.35 3.51e-11 Dermatomyositis; LIHC cis rs6714710 0.603 rs11681535 chr2:98488949 G/C cg26665480 chr2:98280029 ACTR1B 0.44 6.2 0.32 1.67e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg24549020 chr5:56110836 MAP3K1 0.49 6.33 0.32 7.79e-10 Initial pursuit acceleration; LIHC cis rs78545713 0.892 rs11751286 chr6:26241361 C/G cg16070018 chr6:26224392 HIST1H3E 0.62 6.9 0.35 2.5e-11 Iron status biomarkers (total iron binding capacity); LIHC cis rs1577917 0.958 rs12198061 chr6:86550985 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.82 7.76 0.39 9.94e-14 Platelet count; LIHC cis rs11785400 1.000 rs6997670 chr8:143737915 G/A cg24634471 chr8:143751801 JRK 0.52 8.36 0.41 1.55e-15 Schizophrenia; LIHC trans rs2727020 0.823 rs7102374 chr11:49261795 G/A cg03929089 chr4:120376271 NA 0.67 10.0 0.48 8.13e-21 Coronary artery disease; LIHC cis rs7534824 0.543 rs17408457 chr1:101385693 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.7 7.66 0.38 1.97e-13 Refractive astigmatism; LIHC cis rs2637266 0.935 rs2579771 chr10:78407544 A/G cg18941641 chr10:78392320 NA 0.28 6.18 0.32 1.85e-9 Pulmonary function; LIHC trans rs7618501 0.932 rs4855850 chr3:49761571 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.747 rs2742480 chr11:8993130 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -7.02 -0.36 1.18e-11 Hemoglobin concentration; LIHC cis rs9457247 0.967 rs382009 chr6:167403121 G/C cg12798992 chr6:167411361 FGFR1OP 0.6 10.0 0.48 8.15e-21 Crohn's disease; LIHC cis rs8017423 0.933 rs7150378 chr14:90724566 G/A cg04374321 chr14:90722782 PSMC1 0.77 15.42 0.64 4.07e-41 Mortality in heart failure; LIHC cis rs11229555 0.874 rs11605297 chr11:58296806 G/A cg15696309 chr11:58395628 NA -0.72 -8.86 -0.43 4.33e-17 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC trans rs10411161 0.702 rs892039 chr19:52396541 G/A cg22319618 chr22:45562946 NUP50 -0.63 -8.54 -0.42 4.49e-16 Breast cancer; LIHC cis rs2204008 0.837 rs2387317 chr12:38235319 T/C cg26384229 chr12:38710491 ALG10B 0.83 10.31 0.49 6.76e-22 Bladder cancer; LIHC cis rs6748734 1.000 rs10933518 chr2:241838091 A/C cg20140201 chr2:241835670 C2orf54 -0.55 -8.42 -0.41 1.08e-15 Urinary metabolites; LIHC cis rs2439831 0.702 rs7171750 chr15:44025858 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.53 6.49 0.33 2.97e-10 Lung cancer in ever smokers; LIHC cis rs12477438 0.798 rs9679602 chr2:99577827 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.74 10.88 0.51 7.26e-24 Chronic sinus infection; LIHC cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg02290350 chr8:58132656 NA 0.49 8.85 0.43 4.69e-17 Developmental language disorder (linguistic errors); LIHC cis rs6546550 0.935 rs1056482 chr2:70108256 A/T cg02498382 chr2:70120550 SNRNP27 -0.36 -6.03 -0.31 4.24e-9 Prevalent atrial fibrillation; LIHC cis rs7937890 0.559 rs2597188 chr11:14516906 G/A cg02886208 chr11:14281011 SPON1 -0.43 -6.09 -0.31 3.04e-9 Mitochondrial DNA levels; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg19262991 chr12:2113119 DCP1B -0.41 -6.2 -0.32 1.64e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs801193 0.904 rs4718405 chr7:66254646 A/G cg11764359 chr7:65958608 NA 0.71 10.43 0.49 2.77e-22 Aortic root size; LIHC cis rs9916302 0.861 rs4795377 chr17:37669056 C/T cg00129232 chr17:37814104 STARD3 -0.42 -6.74 -0.34 6.84e-11 Glomerular filtration rate (creatinine); LIHC cis rs8062405 1.000 rs7198606 chr16:28875122 T/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg04267008 chr7:1944627 MAD1L1 -0.68 -11.0 -0.51 2.66e-24 Bipolar disorder and schizophrenia; LIHC cis rs1878931 0.597 rs37816 chr16:3456371 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -8.13 -0.4 8.23e-15 Body mass index (adult); LIHC cis rs4925386 0.840 rs6143035 chr20:60920700 C/T cg06026331 chr20:60912101 LAMA5 -0.63 -9.48 -0.46 4.27e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs57590327 0.679 rs13082940 chr3:81547264 C/T cg07356753 chr3:81810745 GBE1 0.48 6.59 0.34 1.69e-10 Extraversion; LIHC cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg09904177 chr6:26538194 HMGN4 0.57 11.54 0.53 2.97e-26 Intelligence (multi-trait analysis); LIHC cis rs3823572 0.564 rs2971953 chr7:133663576 C/T cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.33e-8 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.967 rs8072664 chr17:28333385 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.7 -11.67 -0.53 1.04e-26 Coffee consumption (cups per day); LIHC cis rs5769765 0.908 rs9616396 chr22:50317825 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.72 -9.02 -0.44 1.36e-17 Schizophrenia; LIHC cis rs12291225 0.545 rs11023187 chr11:14345559 T/G cg05501817 chr11:14380813 RRAS2 -0.44 -6.21 -0.32 1.54e-9 Sense of smell; LIHC cis rs2005 1.000 rs2005 chr6:35056443 A/G cg13137465 chr6:34857473 ANKS1A -0.53 -5.84 -0.3 1.19e-8 Obesity-related traits; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg15908580 chr10:134496731 INPP5A -0.43 -6.26 -0.32 1.15e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs16912285 0.535 rs7109619 chr11:24251339 G/A ch.11.24196551F chr11:24239977 NA 0.83 11.81 0.54 3.03e-27 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs6582630 0.576 rs2387836 chr12:38560070 A/G cg26384229 chr12:38710491 ALG10B 0.51 7.04 0.36 1.05e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs10493773 0.775 rs12739713 chr1:86150378 C/T cg17807903 chr1:86174739 ZNHIT6 -0.55 -10.1 -0.48 3.66e-21 Urate levels in overweight individuals; LIHC cis rs2708977 0.933 rs2708976 chr2:97184532 C/G cg01950434 chr2:97203154 ARID5A -0.53 -7.83 -0.39 6.12e-14 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs4700695 1.000 rs153319 chr5:65419423 C/T cg21114390 chr5:65439923 SFRS12 -0.54 -7.16 -0.36 4.83e-12 Facial morphology (factor 19); LIHC cis rs12478296 1.000 rs73007138 chr2:243007041 C/T cg06360820 chr2:242988706 NA -0.95 -11.56 -0.53 2.58e-26 Obesity-related traits; LIHC cis rs2274273 0.934 rs8021940 chr14:55719715 G/A cg04306507 chr14:55594613 LGALS3 0.34 6.5 0.33 2.8e-10 Protein biomarker; LIHC cis rs7552404 1.000 rs12127402 chr1:76205643 C/A cg03433033 chr1:76189801 ACADM 0.63 8.8 0.43 7.04e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6952808 0.825 rs4236277 chr7:1942270 C/T cg14004847 chr7:1930337 MAD1L1 -0.51 -7.27 -0.37 2.54e-12 Bipolar disorder and schizophrenia; LIHC cis rs904251 0.523 rs2797798 chr6:37481437 C/T cg08126542 chr6:37504118 NA -0.37 -6.29 -0.32 9.51e-10 Cognitive performance; LIHC trans rs11098499 0.908 rs11729050 chr4:120300066 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.65 0.42 2.04e-16 Corneal astigmatism; LIHC cis rs11098499 0.954 rs2892848 chr4:120381341 C/T cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs57221529 0.766 rs12519469 chr5:581772 A/G cg09021430 chr5:549028 NA -0.44 -8.71 -0.43 1.29e-16 Lung disease severity in cystic fibrosis; LIHC cis rs1728785 0.901 rs1645974 chr16:68564774 C/G cg02972257 chr16:68554789 NA -0.53 -6.16 -0.32 2e-9 Ulcerative colitis; LIHC cis rs9399135 1.000 rs35123050 chr6:135302740 G/A cg24558204 chr6:135376177 HBS1L 0.39 6.46 0.33 3.67e-10 Red blood cell count; LIHC cis rs921968 0.643 rs2278530 chr2:219501133 G/A cg02985541 chr2:219472218 PLCD4 0.39 7.09 0.36 7.9e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs561341 0.941 rs8081016 chr17:30331751 A/G cg00745463 chr17:30367425 LRRC37B -0.79 -5.92 -0.3 7.98e-9 Hip circumference adjusted for BMI; LIHC cis rs12477438 0.765 rs6749059 chr2:99591021 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.76 -11.4 -0.52 9.54e-26 Chronic sinus infection; LIHC cis rs13191362 1.000 rs34192365 chr6:163012382 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.62 5.78 0.3 1.69e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4727027 0.933 rs10277119 chr7:148849942 T/C cg23583168 chr7:148888333 NA -0.72 -10.3 -0.49 7.5e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs1538970 0.961 rs7543428 chr1:45839643 A/G cg24296786 chr1:45957014 TESK2 -0.49 -7.29 -0.37 2.19e-12 Platelet count; LIHC cis rs12477438 0.520 rs13010904 chr2:99754289 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.17 0.81 7.78e-80 Chronic sinus infection; LIHC cis rs4654899 0.758 rs6694455 chr1:21352185 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.88 0.3 9.68e-9 Superior frontal gyrus grey matter volume; LIHC trans rs9929218 1.000 rs8045022 chr16:68807087 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.7 -0.43 1.41e-16 Colorectal cancer; LIHC cis rs2834188 1.000 rs2834190 chr21:34693011 A/T cg14352951 chr21:34696688 IFNAR1 -0.45 -6.39 -0.33 5.43e-10 Narcolepsy; LIHC cis rs896854 0.517 rs1011795 chr8:95951073 G/A cg16049864 chr8:95962084 TP53INP1 -0.48 -7.87 -0.39 4.66e-14 Type 2 diabetes; LIHC cis rs2251381 0.750 rs2251186 chr21:30528880 G/A cg08807101 chr21:30365312 RNF160 0.76 10.02 0.48 6.72e-21 Selective IgA deficiency; LIHC cis rs3806843 1.000 rs1476768 chr5:140173597 G/A cg19875535 chr5:140030758 IK 0.36 5.84 0.3 1.21e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs4942242 0.640 rs9533563 chr13:44212127 A/G cg19169023 chr15:41853346 TYRO3 -0.51 -7.12 -0.36 6.25e-12 Response to tocilizumab in rheumatoid arthritis; LIHC trans rs2363709 1.000 rs2363714 chr3:67421846 C/G cg15775005 chr18:9136598 ANKRD12 0.79 6.05 0.31 3.71e-9 IgE levels; LIHC cis rs2073300 1.000 rs6137976 chr20:23463241 C/T cg12062639 chr20:23401060 NAPB 0.84 10.22 0.48 1.39e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6061231 0.561 rs67072353 chr20:60940702 G/A cg06026331 chr20:60912101 LAMA5 0.59 6.87 0.35 3.04e-11 Colorectal cancer; LIHC cis rs9549367 0.713 rs510160 chr13:113822481 A/G cg18105134 chr13:113819100 PROZ 0.59 10.04 0.48 5.96e-21 Platelet distribution width; LIHC cis rs2599510 0.811 rs2754520 chr2:32810293 G/A cg02381751 chr2:32503542 YIPF4 0.44 5.72 0.3 2.29e-8 Interleukin-18 levels; LIHC cis rs7216064 1.000 rs73352808 chr17:65875157 G/A cg12091567 chr17:66097778 LOC651250 -0.66 -9.71 -0.46 7.52e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg18305652 chr10:134549665 INPP5A 0.51 8.06 0.4 1.25e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7100689 0.577 rs9420349 chr10:82031160 T/C cg00277334 chr10:82204260 NA -0.49 -5.97 -0.31 6.03e-9 Post bronchodilator FEV1; LIHC cis rs11098499 0.954 rs2389803 chr4:120393511 A/G cg09307838 chr4:120376055 NA -0.78 -11.83 -0.54 2.76e-27 Corneal astigmatism; LIHC cis rs8053891 0.615 rs2000999 chr16:72108093 G/A cg16558253 chr16:72132732 DHX38 -0.54 -7.34 -0.37 1.56e-12 Coronary artery disease; LIHC cis rs3741404 0.620 rs12787945 chr11:63977546 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 12.49 0.56 9.29e-30 Platelet count; LIHC cis rs9911578 1.000 rs437732 chr17:56675861 A/C cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs1385374 0.920 rs61946177 chr12:129273347 C/T cg21616243 chr12:129299702 MGC16384;SLC15A4 0.61 7.42 0.37 9.59e-13 Systemic lupus erythematosus; LIHC cis rs611744 0.901 rs599357 chr8:109194160 T/C cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03900353 chr1:212732456 NA 0.42 6.14 0.32 2.26e-9 Pancreatic cancer; LIHC cis rs2257205 0.667 rs7208872 chr17:56777649 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.8e-10 Pancreatic cancer; LIHC cis rs6750795 0.502 rs11685196 chr2:232381298 A/G cg19187155 chr2:232395269 NMUR1 0.44 7.18 0.36 4.51e-12 Height; LIHC cis rs10845606 0.505 rs2160972 chr12:12838608 C/T cg09462578 chr12:12878428 APOLD1 0.48 7.42 0.37 9.11e-13 Systemic lupus erythematosus; LIHC cis rs921968 0.541 rs526897 chr2:219433597 C/T cg02176678 chr2:219576539 TTLL4 0.52 7.28 0.37 2.28e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs904251 0.523 rs1757191 chr6:37482871 C/T cg01843034 chr6:37503916 NA -0.46 -8.06 -0.4 1.3e-14 Cognitive performance; LIHC cis rs7927771 0.507 rs10838754 chr11:47758532 A/C cg20307385 chr11:47447363 PSMC3 0.72 10.68 0.5 3.75e-23 Subjective well-being; LIHC cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg18252515 chr7:66147081 NA -1.3 -16.9 -0.67 5.23e-47 Diabetic kidney disease; LIHC cis rs7312933 0.558 rs11181467 chr12:42765250 C/T cg17420585 chr12:42539391 GXYLT1 -0.36 -5.91 -0.3 8.19e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10791097 0.694 rs7125622 chr11:130743388 T/C cg14779329 chr11:130786720 SNX19 0.4 6.14 0.32 2.29e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs17125944 0.686 rs8003683 chr14:53366605 G/T cg00686598 chr14:53173677 PSMC6 0.86 9.46 0.46 5.01e-19 Alzheimer's disease (late onset); LIHC cis rs797680 0.786 rs555161 chr1:93676314 A/G cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.65e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs79839061 0.520 rs6842808 chr4:906903 C/T cg12601576 chr4:906860 GAK -0.65 -5.81 -0.3 1.47e-8 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.960 rs9398842 chr6:127674662 T/C cg27446573 chr6:127587934 RNF146 1.06 16.66 0.67 4.93e-46 Breast cancer; LIHC cis rs16958440 1.000 rs4609941 chr18:44645491 T/C cg17192377 chr18:44677553 HDHD2 0.6 6.76 0.34 5.88e-11 Sitting height ratio; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg20295408 chr7:1910781 MAD1L1 -0.49 -7.02 -0.35 1.22e-11 Bipolar disorder and schizophrenia; LIHC cis rs9814567 1.000 rs7426847 chr3:134267519 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs798554 0.679 rs2527681 chr7:2892384 A/T cg13628971 chr7:2884303 GNA12 0.6 10.29 0.49 8.51e-22 Height; LIHC cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg05627663 chr7:65219948 SNORA22;CCT6P1 0.47 10.94 0.51 4.41e-24 Calcium levels; LIHC cis rs7208859 0.725 rs9910051 chr17:29161202 A/T cg14067834 chr17:29058358 SUZ12P 0.61 6.22 0.32 1.49e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4906332 1.000 rs2065017 chr14:103879579 T/C cg19000871 chr14:103996768 TRMT61A -0.45 -7.65 -0.38 2e-13 Coronary artery disease; LIHC trans rs1814175 0.647 rs10769646 chr11:49992204 C/A cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg11494091 chr17:61959527 GH2 0.44 7.89 0.39 4.06e-14 Prudent dietary pattern; LIHC trans rs2727020 0.658 rs7111215 chr11:49430552 T/C cg18944383 chr4:111397179 ENPEP 0.25 6.22 0.32 1.45e-9 Coronary artery disease; LIHC cis rs9902453 0.808 rs76039587 chr17:28233760 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 11.94 0.54 1.03e-27 Coffee consumption (cups per day); LIHC cis rs644799 0.932 rs10831447 chr11:95663017 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.62 -9.12 -0.44 6.46e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7772486 0.875 rs11755334 chr6:146399297 T/C cg23711669 chr6:146136114 FBXO30 0.58 10.0 0.48 8.27e-21 Lobe attachment (rater-scored or self-reported); LIHC cis rs7208859 0.623 rs2035494 chr17:29130393 T/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs7937682 0.921 rs12806479 chr11:111443192 G/C cg09085632 chr11:111637200 PPP2R1B 0.88 9.84 0.47 2.78e-20 Primary sclerosing cholangitis; LIHC trans rs1814175 0.645 rs7123448 chr11:49764865 T/G cg18944383 chr4:111397179 ENPEP 0.27 6.94 0.35 2.02e-11 Height; LIHC cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg11502198 chr6:26597334 ABT1 0.42 6.12 0.31 2.56e-9 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.848 rs6748727 chr2:24041058 G/A cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs4478037 0.822 rs59834381 chr3:33116313 G/A cg16652328 chr3:33138982 GLB1;TMPPE -0.56 -7.13 -0.36 5.98e-12 Major depressive disorder; LIHC cis rs8017423 0.607 rs10142482 chr14:90848280 G/T cg04374321 chr14:90722782 PSMC1 -0.47 -6.89 -0.35 2.61e-11 Mortality in heart failure; LIHC cis rs9611519 0.857 rs4820434 chr22:41637119 G/T cg03806693 chr22:41940476 POLR3H -0.76 -8.26 -0.41 3.28e-15 Neuroticism; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.83 0.39 6.21e-14 Prudent dietary pattern; LIHC cis rs34779708 0.931 rs7908573 chr10:35309513 T/C cg03585969 chr10:35415529 CREM 0.84 12.68 0.57 1.82e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6840360 1.000 rs2007218 chr4:152643972 A/G cg22705602 chr4:152727874 NA 0.33 6.91 0.35 2.38e-11 Intelligence (multi-trait analysis); LIHC cis rs600806 0.745 rs4970763 chr1:110006349 G/A cg23091122 chr1:110024289 SYPL2 -0.48 -6.33 -0.32 7.52e-10 Intelligence (multi-trait analysis); LIHC cis rs875971 0.522 rs1617484 chr7:65463095 G/A cg11764359 chr7:65958608 NA 0.61 8.27 0.41 2.97e-15 Aortic root size; LIHC cis rs7772486 0.686 rs9399564 chr6:146078907 C/T cg23711669 chr6:146136114 FBXO30 -0.7 -12.78 -0.57 7.39e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs7264396 0.635 rs6060675 chr20:34493614 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.5 -0.49 1.57e-22 Total cholesterol levels; LIHC cis rs17685 0.712 rs56965035 chr7:75795670 G/A cg01364799 chr7:75623366 TMEM120A -0.52 -7.74 -0.39 1.13e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -14.26 -0.61 1.61e-36 Alzheimer's disease; LIHC cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 11.66 0.53 1.16e-26 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs35883536 0.647 rs55728953 chr1:101046863 T/C cg14515779 chr1:101123966 NA 0.5 6.9 0.35 2.49e-11 Monocyte count; LIHC trans rs208520 0.526 rs9354366 chr6:66788559 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.05 -20.7 -0.75 2.84e-62 Exhaled nitric oxide output; LIHC cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.92 0.57 2.17e-31 Prudent dietary pattern; LIHC cis rs9814567 0.806 rs4955526 chr3:134317337 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.57 -9.33 -0.45 1.36e-18 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7959452 0.535 rs10878953 chr12:69674187 A/G cg14784868 chr12:69753453 YEATS4 0.84 15.64 0.65 5.7700000000000006e-42 Blood protein levels; LIHC cis rs2067615 0.579 rs4964489 chr12:107171808 A/G cg15890332 chr12:107067104 RFX4 0.26 6.11 0.31 2.66e-9 Heart rate; LIHC cis rs7107174 1.000 rs2450122 chr11:77930345 T/C cg02023728 chr11:77925099 USP35 0.5 9.17 0.44 4.47e-18 Testicular germ cell tumor; LIHC cis rs8103278 0.826 rs11669442 chr19:46374557 A/G cg14061069 chr19:46274453 DMPK -0.48 -7.37 -0.37 1.28e-12 Coronary artery disease; LIHC cis rs7078219 0.505 rs4129133 chr10:101284570 T/C cg06854084 chr10:101292507 NKX2-3 -0.33 -6.06 -0.31 3.63e-9 Dental caries; LIHC trans rs62103177 0.525 rs1835410 chr18:77702025 T/C cg05926928 chr17:57297772 GDPD1 -0.78 -8.56 -0.42 3.87e-16 Opioid sensitivity; LIHC cis rs35306767 0.807 rs12768348 chr10:899224 T/G cg26597838 chr10:835615 NA 1.47 16.88 0.67 6.43e-47 Eosinophil percentage of granulocytes; LIHC trans rs3749237 0.964 rs35210174 chr3:49812606 C/T cg21659725 chr3:3221576 CRBN 0.8 12.45 0.56 1.39e-29 Resting heart rate; LIHC cis rs6545883 0.831 rs1186704 chr2:61672991 A/G cg15711740 chr2:61764176 XPO1 -0.44 -6.1 -0.31 2.86e-9 Tuberculosis; LIHC cis rs1707322 1.000 rs7519181 chr1:46387829 G/C cg06784218 chr1:46089804 CCDC17 0.34 6.03 0.31 4.19e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs992157 0.710 rs12996912 chr2:219110555 A/G cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.53 0.59 1.09e-33 Colorectal cancer; LIHC cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.26e-51 Menopause (age at onset); LIHC cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg13699009 chr12:122356056 WDR66 0.48 8.2 0.41 5.04e-15 Mean corpuscular volume; LIHC cis rs6138458 0.828 rs6132785 chr20:24993414 T/C cg26195577 chr20:24973756 C20orf3 0.91 11.69 0.53 8.96e-27 Blood protein levels; LIHC trans rs17473412 0.677 rs9327298 chr5:122850321 G/A cg04915494 chr16:2962968 FLYWCH1 -0.45 -6.16 -0.32 2.06e-9 Total body bone mineral density; LIHC cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.2e-8 Vitiligo; LIHC cis rs7100689 0.516 rs3862532 chr10:82015725 A/C cg01528321 chr10:82214614 TSPAN14 0.77 10.25 0.48 1.17e-21 Post bronchodilator FEV1; LIHC cis rs174601 0.861 rs174550 chr11:61571478 T/C cg27386326 chr11:61587980 NA 0.7 14.85 0.63 7.91e-39 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; LIHC cis rs2710642 0.611 rs11125941 chr2:62880818 A/C cg17519650 chr2:63277830 OTX1 0.5 7.26 0.37 2.63e-12 LDL cholesterol levels;LDL cholesterol; LIHC cis rs7428 0.545 rs17026212 chr2:85551696 T/G cg24342717 chr2:85555507 TGOLN2 -0.77 -10.74 -0.5 2.26e-23 Ear protrusion; LIHC cis rs523522 0.962 rs4766966 chr12:120942911 G/C cg27279351 chr12:120934652 DYNLL1 0.66 11.89 0.54 1.63e-27 High light scatter reticulocyte count; LIHC cis rs208520 0.754 rs851592 chr6:66875175 G/T cg07460842 chr6:66804631 NA -0.79 -8.82 -0.43 5.87e-17 Exhaled nitric oxide output; LIHC cis rs1789 0.903 rs4453929 chr4:15672173 T/G cg21123203 chr4:15471301 CC2D2A -0.43 -6.78 -0.34 5.25e-11 Blood protein levels; LIHC cis rs937213 0.676 rs8042456 chr15:40290476 G/T cg01081584 chr15:40268610 EIF2AK4 -0.47 -7.4 -0.37 1.04e-12 Endometrial cancer;Endometrial endometrioid carcinoma; LIHC cis rs701145 0.556 rs355779 chr3:153977253 T/C cg16511985 chr3:153974050 SGEF 0.42 8.95 0.44 2.28e-17 Coronary artery disease; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07242783 chr1:28052377 FAM76A 0.51 6.31 0.32 8.72e-10 Lung function (FEV1/FVC); LIHC cis rs7917772 0.560 rs35095897 chr10:104377759 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.58 -0.38 3.2e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7412746 0.658 rs8444 chr1:150938571 G/A cg18016565 chr1:150552671 MCL1 0.52 9.71 0.46 7.58e-20 Melanoma; LIHC cis rs2228479 0.850 rs17227263 chr16:89810598 G/A cg00800038 chr16:89945340 TCF25 -0.61 -8.89 -0.43 3.56e-17 Skin colour saturation; LIHC cis rs4908768 0.555 rs55939938 chr1:8863664 A/T cg20416874 chr1:8611966 RERE 0.43 6.54 0.33 2.27e-10 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs1878931 0.624 rs27235 chr16:3439138 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.7 -9.16 -0.44 4.87e-18 Body mass index (adult); LIHC cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg10150615 chr22:24372951 LOC391322 -0.57 -8.5 -0.42 5.78e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2645694 0.533 rs2645680 chr4:77820956 T/C cg06046430 chr4:77819534 ANKRD56 0.5 6.54 0.33 2.31e-10 Emphysema distribution in smoking; LIHC cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg26338869 chr17:61819248 STRADA 0.61 8.71 0.43 1.33e-16 Prudent dietary pattern; LIHC cis rs240764 0.658 rs4840147 chr6:101182323 T/C cg09795085 chr6:101329169 ASCC3 -0.45 -6.59 -0.34 1.66e-10 Neuroticism; LIHC cis rs7659604 1.000 rs7660078 chr4:122665577 G/T cg19748678 chr4:122722346 EXOSC9 0.35 5.77 0.3 1.75e-8 Type 2 diabetes; LIHC cis rs7937890 0.587 rs11023204 chr11:14411223 C/A cg23387056 chr11:14280742 SPON1 -0.43 -5.85 -0.3 1.16e-8 Mitochondrial DNA levels; LIHC cis rs6815814 0.898 rs73236646 chr4:38871385 T/C cg06935464 chr4:38784597 TLR10 0.41 6.13 0.31 2.48e-9 Breast cancer; LIHC trans rs801193 0.844 rs732465 chr7:65998450 T/C cg26939375 chr7:64535504 NA 0.44 7.5 0.38 5.68e-13 Aortic root size; LIHC cis rs10861342 1.000 rs12316054 chr12:105569143 T/C cg23923672 chr12:105501055 KIAA1033 0.67 7.78 0.39 8.56e-14 IgG glycosylation; LIHC trans rs11785693 0.862 rs11782343 chr8:5001642 C/G cg15684290 chr8:6263623 MCPH1 0.49 6.84 0.35 3.57e-11 Neuroticism (multi-trait analysis);Neuroticism; LIHC cis rs9359856 0.564 rs72913954 chr6:90361589 T/C cg13799429 chr6:90582589 CASP8AP2 -0.64 -5.97 -0.31 6.07e-9 Bipolar disorder; LIHC cis rs7607369 0.526 rs4674322 chr2:219513782 C/T cg02176678 chr2:219576539 TTLL4 0.63 7.15 0.36 5.29e-12 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs6963495 0.719 rs73190172 chr7:105161210 T/C cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs3845702 0.736 rs72962517 chr2:180861452 G/A cg01881094 chr2:180872142 CWC22 1.12 9.94 0.47 1.24e-20 Schizophrenia; LIHC cis rs17826219 0.706 rs28469200 chr17:29133572 T/A cg14067834 chr17:29058358 SUZ12P 0.73 7.42 0.37 9.65e-13 Body mass index; LIHC cis rs10463316 0.894 rs7729438 chr5:150762197 G/A cg03212797 chr5:150827313 SLC36A1 -0.45 -6.76 -0.34 5.87e-11 Metabolite levels (Pyroglutamine); LIHC cis rs4819052 0.819 rs13046807 chr21:46672286 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 11.23 0.52 4.19e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4820294 1.000 rs41280035 chr22:38054038 A/G cg00142150 chr22:38071001 LGALS1 0.67 11.0 0.51 2.66e-24 Fat distribution (HIV); LIHC trans rs4843747 0.671 rs28679286 chr16:88106307 C/T cg09572067 chr16:29127029 RRN3P2 0.5 8.0 0.4 1.94e-14 Menopause (age at onset); LIHC cis rs8114671 0.562 rs725521 chr20:33516071 T/C cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.01e-19 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg07254608 chr8:41997973 NA 0.43 6.83 0.35 4e-11 Cognitive function; LIHC cis rs6499255 1.000 rs73579458 chr16:69804764 G/C cg15192750 chr16:69999425 NA 0.46 6.8 0.35 4.54e-11 IgE levels; LIHC cis rs12464559 0.649 rs4306714 chr2:152611351 G/A cg01189475 chr2:152685088 ARL5A 0.63 7.32 0.37 1.75e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7258465 1.000 rs4808133 chr19:18608518 C/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.5 -0.38 5.38e-13 Breast cancer; LIHC cis rs72781680 0.898 rs17762609 chr2:24114729 G/T cg08917208 chr2:24149416 ATAD2B 0.87 8.2 0.41 4.78e-15 Lymphocyte counts; LIHC cis rs712039 0.652 rs853227 chr17:35797529 C/T cg16670864 chr17:35848621 DUSP14 0.35 5.95 0.31 6.46e-9 Tuberculosis; LIHC cis rs6570726 0.599 rs9376951 chr6:145898911 C/T cg23711669 chr6:146136114 FBXO30 0.63 9.33 0.45 1.39e-18 Lobe attachment (rater-scored or self-reported); LIHC cis rs7116495 0.609 rs2508860 chr11:71805052 C/T cg10381502 chr11:71823885 C11orf51 1.07 8.88 0.43 3.79e-17 Severe influenza A (H1N1) infection; LIHC cis rs2842992 0.789 rs2342446 chr6:160220687 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.52 8.95 0.44 2.28e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs7772486 0.875 rs2814873 chr6:146308932 T/C cg13319975 chr6:146136371 FBXO30 -0.39 -6.3 -0.32 9.41e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs459571 0.959 rs455381 chr9:136905577 C/A cg13789015 chr9:136890014 NCRNA00094 0.46 8.3 0.41 2.44e-15 Platelet distribution width; LIHC cis rs13088318 0.504 rs9828111 chr3:101197777 C/T cg19452782 chr3:101232218 SENP7 0.41 6.12 0.31 2.5e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs4478858 0.735 rs4949389 chr1:31824023 A/G cg00250761 chr1:31883323 NA 0.29 6.26 0.32 1.13e-9 Alcohol dependence; LIHC trans rs7618501 1.000 rs6802890 chr3:49832261 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.8 14.58 0.62 8.37e-38 Intelligence (multi-trait analysis); LIHC cis rs7223966 0.960 rs2319990 chr17:61705397 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 6.96 0.35 1.7e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs34779708 0.931 rs3740083 chr10:35320383 C/T cg03585969 chr10:35415529 CREM 0.84 12.66 0.56 2.25e-30 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11204677 1 rs11204677 chr1:150574695 C/G cg17724175 chr1:150552817 MCL1 -0.37 -7.53 -0.38 4.46e-13 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC cis rs963731 0.649 rs1454221 chr2:39215672 C/T cg04010122 chr2:39346883 SOS1 -0.68 -5.8 -0.3 1.55e-8 Corticobasal degeneration; LIHC cis rs722599 0.748 rs731165 chr14:75352555 T/C cg11812906 chr14:75593930 NEK9 -0.45 -7.22 -0.36 3.36e-12 IgG glycosylation; LIHC cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg06481639 chr22:41940642 POLR3H -0.74 -7.48 -0.37 6.46e-13 Vitiligo; LIHC trans rs73186030 0.841 rs112779893 chr3:122053280 C/T cg13973942 chr17:977984 ABR 0.47 6.06 0.31 3.54e-9 Serum parathyroid hormone levels; LIHC cis rs732505 1.000 rs732505 chr19:5582535 G/A cg26242866 chr19:5711310 LONP1 0.88 6.52 0.33 2.55e-10 vWF and FVIII levels; LIHC cis rs4819052 0.679 rs28623526 chr21:46712324 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.66 10.25 0.48 1.1e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg19355462 chr6:15248936 JARID2 -0.53 -6.16 -0.32 2.01e-9 Systolic blood pressure; LIHC cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg04267008 chr7:1944627 MAD1L1 -0.69 -11.45 -0.53 6.37e-26 Bipolar disorder and schizophrenia; LIHC cis rs7572733 0.515 rs1518368 chr2:198839145 G/A cg00792783 chr2:198669748 PLCL1 0.45 6.62 0.34 1.42e-10 Dermatomyositis; LIHC cis rs79149102 0.579 rs78664321 chr15:75339575 G/A cg09165964 chr15:75287851 SCAMP5 -0.63 -7.9 -0.39 3.94e-14 Lung cancer; LIHC cis rs919433 0.617 rs13018267 chr2:198545592 G/C cg10820045 chr2:198174542 NA -0.49 -7.5 -0.38 5.38e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6546550 0.901 rs6736408 chr2:70137774 C/T cg02498382 chr2:70120550 SNRNP27 -0.44 -7.59 -0.38 2.98e-13 Prevalent atrial fibrillation; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11266582 chr15:64275853 DAPK2 0.41 6.08 0.31 3.19e-9 Immature fraction of reticulocytes; LIHC cis rs1577917 1.000 rs12216328 chr6:86703418 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.49 -0.33 2.99e-10 Response to antipsychotic treatment; LIHC cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg11502198 chr6:26597334 ABT1 0.61 9.71 0.47 7.37e-20 Intelligence (multi-trait analysis); LIHC cis rs7911264 0.967 rs9419741 chr10:94430525 A/G cg25506282 chr10:94462361 NA -0.44 -7.48 -0.37 6.29e-13 Inflammatory bowel disease; LIHC cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg06238570 chr21:40685208 BRWD1 -0.39 -6.27 -0.32 1.08e-9 Menarche (age at onset); LIHC cis rs7605378 0.528 rs281787 chr2:200784238 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.54 -7.21 -0.36 3.55e-12 Osteoporosis; LIHC cis rs847649 1.000 rs12537977 chr7:102539230 C/T cg18108683 chr7:102477205 FBXL13 -0.48 -7.2 -0.36 3.84e-12 Morning vs. evening chronotype; LIHC trans rs75804782 0.521 rs2117691 chr2:239414734 C/T cg01134436 chr17:81009848 B3GNTL1 0.78 6.66 0.34 1.12e-10 Morning vs. evening chronotype;Chronotype; LIHC cis rs2153535 0.580 rs7743418 chr6:8438128 A/C cg23788917 chr6:8435910 SLC35B3 0.61 8.64 0.42 2.2e-16 Motion sickness; LIHC cis rs362296 0.661 rs3121420 chr4:3264210 T/C cg06533319 chr4:3265114 C4orf44 0.36 6.98 0.35 1.55e-11 Parental longevity (mother's age at death); LIHC cis rs2066819 1.000 rs74673257 chr12:56638077 T/C cg26714650 chr12:56694279 CS -1.33 -12.81 -0.57 5.98e-31 Psoriasis vulgaris; LIHC cis rs7945705 0.967 rs10769968 chr11:8907583 G/C cg12365402 chr11:9010492 NRIP3 0.29 7.59 0.38 3.12e-13 Hemoglobin concentration; LIHC cis rs7847628 0.666 rs2031974 chr9:123527521 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.73 11.45 0.53 6.43e-26 Birth weight; LIHC cis rs7772486 0.875 rs2814874 chr6:146305895 C/T cg23711669 chr6:146136114 FBXO30 0.67 11.44 0.53 6.89e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.9 -9.94 -0.47 1.25e-20 Alzheimer's disease; LIHC cis rs2404602 1.000 rs2896954 chr15:76851692 C/A cg23625390 chr15:77176239 SCAPER 0.41 6.86 0.35 3.15e-11 Blood metabolite levels; LIHC cis rs778371 0.676 rs4973563 chr2:233716421 C/T cg08000102 chr2:233561755 GIGYF2 -0.77 -9.37 -0.45 9.86e-19 Schizophrenia; LIHC cis rs9326248 0.817 rs6589598 chr11:117002403 A/G cg26566898 chr11:117069891 TAGLN 0.39 5.91 0.3 8.28e-9 Blood protein levels; LIHC cis rs2070488 0.804 rs2268755 chr3:38501916 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.75 -12.82 -0.57 5.2500000000000004e-31 Electrocardiographic conduction measures; LIHC cis rs2066819 1.000 rs74496027 chr12:56726340 C/T cg26714650 chr12:56694279 CS -1.38 -13.72 -0.6 2e-34 Psoriasis vulgaris; LIHC cis rs6710529 1 rs6710529 chr2:219645553 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.48 -0.33 3.23e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs748404 0.560 rs570933 chr15:43824030 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.37 6.05 0.31 3.73e-9 Lung cancer; LIHC trans rs9914544 1.000 rs28436199 chr17:18751730 C/T cg21372672 chr17:16614065 CCDC144A -0.27 -6.04 -0.31 4.06e-9 Educational attainment (years of education); LIHC cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg05368731 chr17:41323189 NBR1 0.73 12.61 0.56 3.33e-30 Menopause (age at onset); LIHC cis rs72627123 0.867 rs57731447 chr14:74487521 G/A cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.56 0.46 2.44e-19 Morning vs. evening chronotype; LIHC cis rs1552244 0.882 rs68080705 chr3:10025743 C/T cg08888203 chr3:10149979 C3orf24 0.47 6.1 0.31 2.85e-9 Alzheimer's disease; LIHC cis rs2404602 0.716 rs17362383 chr15:76650702 A/G cg23625390 chr15:77176239 SCAPER 0.36 6.0 0.31 5.01e-9 Blood metabolite levels; LIHC cis rs2204008 0.837 rs4432085 chr12:38181146 C/T cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs853679 0.517 rs4713141 chr6:28101678 G/C cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs17685 0.753 rs2302438 chr7:75677065 C/A cg04592579 chr7:75616294 TMEM120A 0.38 6.62 0.34 1.4e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7246657 0.943 rs10420430 chr19:37894194 C/G cg23950597 chr19:37808831 NA -0.49 -6.4 -0.33 5.02e-10 Coronary artery calcification; LIHC cis rs600806 0.778 rs891379 chr1:110003605 A/G cg10127483 chr1:110009974 SYPL2 0.49 5.99 0.31 5.43e-9 Intelligence (multi-trait analysis); LIHC cis rs4242434 0.854 rs3064 chr8:22451688 C/G cg21658235 chr8:22456391 C8orf58 -0.35 -5.72 -0.3 2.37e-8 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); LIHC cis rs61677309 1.000 rs2120269 chr11:118151135 T/C cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs9814567 1.000 rs28409322 chr3:134252385 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11190604 1.000 rs2295779 chr10:102296061 A/G cg07080220 chr10:102295463 HIF1AN 0.55 8.18 0.4 5.55e-15 Palmitoleic acid (16:1n-7) levels; LIHC cis rs3020736 0.500 rs5996109 chr22:42493098 A/G cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.05 -0.31 3.75e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs1055129 0.560 rs2305913 chr17:73922941 T/C cg14829360 chr17:73884958 NA -0.38 -6.42 -0.33 4.59e-10 White matter hyperintensity burden; LIHC trans rs12310956 0.532 rs1906134 chr12:33957135 A/C cg26384229 chr12:38710491 ALG10B 0.54 7.46 0.37 7.17e-13 Morning vs. evening chronotype; LIHC cis rs7582720 1.000 rs72934737 chr2:203740798 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1707322 1.000 rs4641257 chr1:46353589 G/A cg03146154 chr1:46216737 IPP 0.47 7.68 0.38 1.69e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs881375 0.967 rs7848332 chr9:123669496 T/C cg14580859 chr9:123691850 NA 0.39 6.83 0.35 3.96e-11 Rheumatoid arthritis; LIHC cis rs79387448 0.745 rs6742433 chr2:103175360 C/T cg09003973 chr2:102972529 NA 0.87 7.51 0.38 5.22e-13 Gut microbiota (bacterial taxa); LIHC cis rs765787 0.530 rs1706832 chr15:45517173 C/T cg25801113 chr15:45476975 SHF 0.37 6.16 0.32 2.05e-9 Uric acid levels; LIHC cis rs12220238 0.822 rs11000979 chr10:76067865 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.62 5.92 0.3 7.77e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs1395 0.778 rs60631624 chr2:27497815 T/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -5.82 -0.3 1.37e-8 Blood metabolite levels; LIHC cis rs7520050 0.966 rs6661910 chr1:46290632 A/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.76 0.3 1.91e-8 Red blood cell count;Reticulocyte count; LIHC cis rs12497850 0.805 rs6446198 chr3:49007638 T/A cg07636037 chr3:49044803 WDR6 0.93 16.31 0.66 1.25e-44 Parkinson's disease; LIHC trans rs1864585 0.520 rs7817252 chr8:10685932 C/A cg20373634 chr10:103911536 NOLC1 -0.46 -6.08 -0.31 3.3e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs3749237 0.537 rs4459909 chr3:49469217 T/C cg03060546 chr3:49711283 APEH 0.6 9.97 0.47 9.89e-21 Resting heart rate; LIHC cis rs3096299 0.748 rs3102339 chr16:89442711 C/T cg06640241 chr16:89574553 SPG7 0.61 9.58 0.46 2.12e-19 Multiple myeloma (IgH translocation); LIHC cis rs963731 0.649 rs10186762 chr2:39219361 A/G cg04010122 chr2:39346883 SOS1 -0.7 -5.96 -0.31 6.38e-9 Corticobasal degeneration; LIHC cis rs780096 0.526 rs1260342 chr2:27663416 G/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs7520050 0.966 rs6669522 chr1:46397941 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.71 0.3 2.41e-8 Red blood cell count;Reticulocyte count; LIHC cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg03351412 chr1:154909251 PMVK 0.7 10.35 0.49 5.21e-22 Prostate cancer; LIHC cis rs1559088 0.948 rs7247748 chr19:33594023 T/C cg27124370 chr19:33622961 WDR88 0.52 8.26 0.41 3.29e-15 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs716804 0.703 rs12419593 chr11:10289030 G/A cg01453529 chr11:10209919 SBF2 -0.29 -5.87 -0.3 1.01e-8 Neuroticism; LIHC trans rs4942242 0.663 rs7319346 chr13:44218201 T/C cg19169023 chr15:41853346 TYRO3 -0.54 -7.5 -0.38 5.73e-13 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs10752881 0.839 rs2093983 chr1:183094210 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.57 0.5 8.66e-23 Colorectal cancer; LIHC cis rs10644111 1 rs10644111 chr7:91652178 A/AAAC cg17063962 chr7:91808500 NA 1.03 20.71 0.75 2.54e-62 Breast cancer; LIHC cis rs700651 0.757 rs6748683 chr2:198878008 T/A cg00792783 chr2:198669748 PLCL1 0.42 6.08 0.31 3.15e-9 Intracranial aneurysm; LIHC cis rs11758351 0.587 rs2050950 chr6:26234883 A/G cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg14379462 chr9:136234288 SURF4 0.43 6.89 0.35 2.73e-11 Longevity; LIHC cis rs9911578 0.967 rs12603238 chr17:57130785 C/T cg05425664 chr17:57184151 TRIM37 0.59 8.81 0.43 6.36e-17 Intelligence (multi-trait analysis); LIHC cis rs12478296 0.818 rs57194240 chr2:243011545 A/G cg06360820 chr2:242988706 NA -0.82 -12.21 -0.55 1.01e-28 Obesity-related traits; LIHC cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg13393036 chr8:95962371 TP53INP1 0.37 8.26 0.41 3.22e-15 Type 2 diabetes; LIHC cis rs79057730 0.639 rs6463933 chr7:793954 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.78 8.72 0.43 1.23e-16 Initial pursuit acceleration; LIHC cis rs769267 0.965 rs2315024 chr19:19423817 T/A cg03709012 chr19:19516395 GATAD2A 0.91 15.08 0.63 9.62e-40 Tonsillectomy; LIHC cis rs3806843 1.000 rs1030164 chr5:140185272 A/G cg19875535 chr5:140030758 IK 0.36 5.88 0.3 9.83e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs881375 1.000 rs10760118 chr9:123641616 C/T cg14580859 chr9:123691850 NA 0.37 6.37 0.33 6.11e-10 Rheumatoid arthritis; LIHC cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg04267008 chr7:1944627 MAD1L1 0.62 9.55 0.46 2.6e-19 Bipolar disorder and schizophrenia; LIHC cis rs9389248 0.737 rs56358308 chr6:135306980 A/T cg24558204 chr6:135376177 HBS1L 0.6 10.38 0.49 4.14e-22 High light scatter reticulocyte percentage of red cells; LIHC cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg26338869 chr17:61819248 STRADA 0.61 8.88 0.43 3.86e-17 Prudent dietary pattern; LIHC trans rs2243480 1.000 rs35820085 chr7:65442758 C/T cg10756647 chr7:56101905 PSPH 1.1 13.27 0.58 1.01e-32 Diabetic kidney disease; LIHC cis rs3015497 0.616 rs4901043 chr14:51083594 C/T cg09863266 chr14:51125203 SAV1 0.37 5.94 0.31 7.07e-9 Mean platelet volume; LIHC cis rs9811920 0.638 rs7629426 chr3:99652577 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.49 6.91 0.35 2.37e-11 Axial length; LIHC cis rs9914988 0.943 rs7215310 chr17:27088626 G/T cg20469991 chr17:27169893 C17orf63 -0.51 -6.05 -0.31 3.72e-9 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs950169 0.580 rs2271431 chr15:85189464 A/C cg17507749 chr15:85114479 UBE2QP1 0.66 7.66 0.38 1.93e-13 Schizophrenia; LIHC cis rs59901009 0.911 rs61889955 chr11:10183445 G/T cg01453529 chr11:10209919 SBF2 -0.31 -6.1 -0.31 2.87e-9 Hematocrit;Hemoglobin concentration; LIHC cis rs1190552 0.894 rs2236349 chr14:102963640 G/A cg10241871 chr14:102965420 TECPR2 -0.49 -7.49 -0.38 5.93e-13 Blood protein levels; LIHC cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg18357526 chr6:26021779 HIST1H4A 0.58 8.04 0.4 1.49e-14 Blood metabolite levels; LIHC cis rs9896933 0.615 rs2379354 chr17:80704385 G/A cg15664640 chr17:80829946 TBCD -0.6 -5.91 -0.3 8.34e-9 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs2439831 0.867 rs4075674 chr15:43650230 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.91 16.93 0.68 3.9e-47 Lung cancer in ever smokers; LIHC cis rs918629 0.716 rs6861531 chr5:95274702 A/G cg10483112 chr5:95245456 ELL2 -0.35 -6.02 -0.31 4.47e-9 IgG glycosylation; LIHC cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg23283495 chr1:209979779 IRF6 0.47 7.56 0.38 3.77e-13 Cleft lip with or without cleft palate; LIHC cis rs7617773 0.539 rs35460860 chr3:48392085 A/T cg11946769 chr3:48343235 NME6 0.55 6.78 0.34 5.21e-11 Coronary artery disease; LIHC trans rs7618501 0.633 rs2883057 chr3:49998282 C/T cg21659725 chr3:3221576 CRBN 0.69 11.22 0.52 4.39e-25 Intelligence (multi-trait analysis); LIHC cis rs12986413 0.624 rs12460763 chr19:2138507 A/G cg09261902 chr19:2140048 AP3D1 0.4 6.83 0.35 3.92e-11 Height; LIHC trans rs10411161 1.000 rs10409331 chr19:52370962 C/T cg22319618 chr22:45562946 NUP50 -0.51 -6.83 -0.35 3.78e-11 Breast cancer; LIHC cis rs12908161 0.920 rs35738019 chr15:85280210 T/C cg17507749 chr15:85114479 UBE2QP1 0.64 7.39 0.37 1.15e-12 Schizophrenia; LIHC cis rs2976388 0.609 rs2585153 chr8:143785345 G/A cg06565975 chr8:143823917 SLURP1 0.34 6.72 0.34 7.51e-11 Urinary tract infection frequency; LIHC cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg00280220 chr17:61926910 NA 0.41 6.67 0.34 1.02e-10 Prudent dietary pattern; LIHC cis rs11148252 0.811 rs9535895 chr13:52765847 G/A cg00495681 chr13:53174319 NA 0.42 6.76 0.34 5.87e-11 Lewy body disease; LIHC cis rs7617773 0.780 rs34749846 chr3:48347168 T/G cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs909341 0.680 rs2427534 chr20:62366478 A/G cg03999872 chr20:62272968 STMN3 -0.46 -6.83 -0.35 3.93e-11 Atopic dermatitis; LIHC cis rs7937890 1.000 rs2970335 chr11:14325401 A/C cg02251663 chr11:14281053 SPON1 -0.42 -5.83 -0.3 1.29e-8 Mitochondrial DNA levels; LIHC cis rs2204008 0.744 rs11168870 chr12:37973333 A/G cg13010199 chr12:38710504 ALG10B 0.49 5.72 0.3 2.3e-8 Bladder cancer; LIHC cis rs8017423 0.647 rs11623736 chr14:90746471 G/T cg04374321 chr14:90722782 PSMC1 -0.78 -14.81 -0.63 1.12e-38 Mortality in heart failure; LIHC cis rs6933660 0.800 rs9383893 chr6:151757327 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.54 -8.16 -0.4 6.54e-15 Menarche (age at onset); LIHC cis rs11685299 1 rs11685299 chr2:225391296 C/A cg12698349 chr2:225449008 CUL3 0.8 13.96 0.6 2.27e-35 Schizophrenia; LIHC cis rs10861342 0.515 rs10861340 chr12:105454097 C/T cg23923672 chr12:105501055 KIAA1033 -0.44 -6.31 -0.32 8.63e-10 IgG glycosylation; LIHC cis rs7520050 0.966 rs12409773 chr1:46358831 A/G cg03146154 chr1:46216737 IPP -0.38 -6.21 -0.32 1.52e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4820294 1.000 rs929039 chr22:38071511 T/C cg00292662 chr22:38071168 LGALS1 0.63 9.87 0.47 2.19e-20 Fat distribution (HIV); LIHC cis rs3849570 1.000 rs4411908 chr3:81802418 A/C cg07356753 chr3:81810745 GBE1 -0.6 -8.22 -0.41 4.16e-15 Waist circumference;Body mass index; LIHC cis rs6429082 0.714 rs184108 chr1:235646160 A/G cg26050004 chr1:235667680 B3GALNT2 0.51 7.95 0.4 2.7e-14 Adiposity; LIHC cis rs10504229 0.813 rs6999878 chr8:58197243 C/G cg02290350 chr8:58132656 NA 0.33 6.52 0.33 2.47e-10 Developmental language disorder (linguistic errors); LIHC cis rs8141529 0.687 rs6005867 chr22:29165120 T/C cg02153584 chr22:29168773 CCDC117 0.56 8.88 0.43 3.93e-17 Lymphocyte counts; LIHC cis rs4665809 1.000 rs6546767 chr2:26328746 A/G cg04944784 chr2:26401820 FAM59B -0.65 -8.27 -0.41 3.05e-15 Gut microbiome composition (summer); LIHC cis rs4700695 0.719 rs27588 chr5:65459360 C/A cg21114390 chr5:65439923 SFRS12 -0.57 -8.16 -0.4 6.7e-15 Facial morphology (factor 19); LIHC cis rs3862030 0.720 rs2025713 chr10:104230156 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.27 -0.37 2.42e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs11792861 0.619 rs2289480 chr9:111705501 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.69 11.4 0.52 1.01e-25 Menarche (age at onset); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg10527288 chr14:93582455 ITPK1 -0.52 -6.48 -0.33 3.24e-10 Systolic blood pressure; LIHC cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg02635209 chr6:118822505 C6orf204;BRD7P3 0.57 5.83 0.3 1.3e-8 Diastolic blood pressure; LIHC cis rs225245 0.817 rs225269 chr17:33967931 G/T cg05299278 chr17:33885742 SLFN14 0.23 6.25 0.32 1.25e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs10540 1.000 rs61876342 chr11:496193 T/G cg03352830 chr11:487213 PTDSS2 0.83 7.01 0.35 1.28e-11 Body mass index; LIHC cis rs2439831 0.850 rs16963953 chr15:44081719 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.39 0.33 5.53e-10 Lung cancer in ever smokers; LIHC cis rs2292096 0.636 rs6427855 chr1:200726579 A/G cg11814564 chr1:200748674 CAMSAP1L1 -0.56 -10.63 -0.5 5.3e-23 Epilepsy; LIHC cis rs1348850 0.574 rs4893835 chr2:178442592 T/C cg27490568 chr2:178487706 NA 0.95 11.3 0.52 2.18e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC trans rs875971 0.545 rs75577046 chr7:65958716 A/G cg26939375 chr7:64535504 NA 0.42 6.63 0.34 1.32e-10 Aortic root size; LIHC cis rs9467773 1.000 rs9467787 chr6:26556769 G/T cg11502198 chr6:26597334 ABT1 0.45 6.57 0.33 1.85e-10 Intelligence (multi-trait analysis); LIHC cis rs2404602 0.692 rs4641709 chr15:77047736 C/T cg23625390 chr15:77176239 SCAPER -0.36 -5.96 -0.31 6.43e-9 Blood metabolite levels; LIHC cis rs9303401 0.625 rs10515159 chr17:56802693 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.96 13.17 0.58 2.63e-32 Cognitive test performance; LIHC cis rs2073300 0.826 rs6048809 chr20:23443788 C/T cg16736954 chr20:23401023 NAPB 0.52 5.79 0.3 1.64e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg12419862 chr22:24373484 LOC391322 -0.75 -11.26 -0.52 3.21e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs12586317 0.547 rs2383693 chr14:35500205 A/C cg05294307 chr14:35346193 BAZ1A -0.51 -7.6 -0.38 2.93e-13 Psoriasis; LIHC cis rs10883723 0.810 rs2296585 chr10:104245549 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 12.86 0.57 3.8e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs72627509 0.629 rs1277313 chr4:57903948 A/C cg26694713 chr4:57773883 REST -0.43 -5.89 -0.3 9.07e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs870825 0.929 rs72689265 chr4:185590982 A/G cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs7829975 0.533 rs13274028 chr8:8729193 A/C cg06636001 chr8:8085503 FLJ10661 0.36 6.43 0.33 4.26e-10 Mood instability; LIHC cis rs11018874 0.532 rs11018867 chr11:89862345 C/T cg05041596 chr11:89867385 NAALAD2 0.43 7.29 0.37 2.2e-12 White blood cell types; LIHC trans rs9747201 1.000 rs55638685 chr17:80107566 G/C cg07393940 chr7:158741817 NA -0.57 -6.95 -0.35 1.85e-11 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2153535 0.542 rs915353 chr6:8440370 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs11945232 1.000 rs28406846 chr4:88343468 C/G cg23841344 chr4:88312519 HSD17B11 -0.55 -7.14 -0.36 5.67e-12 Intelligence (multi-trait analysis); LIHC cis rs597539 0.616 rs473997 chr11:68639481 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.3 0.49 7.85e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs74544699 1.000 rs11574452 chr4:74846661 A/C cg02530824 chr4:74847766 PF4 -0.65 -7.07 -0.36 8.71e-12 Growth-regulated protein alpha levels; LIHC cis rs6088580 0.601 rs6059872 chr20:33082775 C/A cg08999081 chr20:33150536 PIGU 0.67 13.46 0.59 1.89e-33 Glomerular filtration rate (creatinine); LIHC cis rs7551222 0.752 rs11240755 chr1:204478649 C/T cg20240347 chr1:204465584 NA -0.35 -7.48 -0.37 6.51e-13 Schizophrenia; LIHC cis rs875971 0.862 rs7798630 chr7:65771479 G/C cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC cis rs12497850 0.931 rs7647813 chr3:48833348 G/T cg07636037 chr3:49044803 WDR6 0.93 17.07 0.68 1.12e-47 Parkinson's disease; LIHC trans rs3783890 0.887 rs11621101 chr14:93805880 C/T cg02802420 chr16:69363236 PDF;COG8 0.33 6.26 0.32 1.15e-9 Body mass index; LIHC cis rs8053891 0.708 rs8055242 chr16:72006882 C/T cg01557791 chr16:72042693 DHODH -0.5 -7.09 -0.36 7.9e-12 Coronary artery disease; LIHC cis rs2257205 0.667 rs7220884 chr17:56743948 G/A cg05425664 chr17:57184151 TRIM37 -0.59 -6.47 -0.33 3.49e-10 Pancreatic cancer; LIHC cis rs11031096 0.655 rs10835695 chr11:4178962 G/T cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.46e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs11792861 0.816 rs7021366 chr9:111727670 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 9.22 0.45 3.14e-18 Menarche (age at onset); LIHC cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg22633049 chr21:46681294 NA -0.38 -6.57 -0.33 1.89e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7589728 0.858 rs79992736 chr2:88530575 A/C cg04511125 chr2:88470314 THNSL2 0.82 8.33 0.41 2e-15 Plasma clusterin levels; LIHC cis rs8062405 1.000 rs3888190 chr16:28889486 C/A cg16576597 chr16:28551801 NUPR1 0.37 6.14 0.31 2.34e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs8067545 0.611 rs2703807 chr17:20109189 C/T cg13482628 chr17:19912719 NA -0.43 -7.0 -0.35 1.34e-11 Schizophrenia; LIHC cis rs7224685 0.501 rs2054038 chr17:4014391 A/C cg09597638 chr17:3907349 NA 0.61 10.74 0.5 2.17e-23 Type 2 diabetes; LIHC cis rs2380220 0.516 rs7748108 chr6:96008082 T/C cg15832292 chr6:96025679 MANEA 0.62 8.67 0.42 1.74e-16 Behavioural disinhibition (generation interaction); LIHC cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg17971929 chr21:40555470 PSMG1 -0.41 -6.19 -0.32 1.73e-9 Menarche (age at onset); LIHC cis rs769267 0.930 rs4808203 chr19:19568659 A/G cg03709012 chr19:19516395 GATAD2A 1.03 18.13 0.7 5.97e-52 Tonsillectomy; LIHC cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg26338869 chr17:61819248 STRADA 0.61 8.84 0.43 4.98e-17 Prudent dietary pattern; LIHC cis rs9420 0.961 rs17455520 chr11:57540458 C/A cg19752551 chr11:57585705 CTNND1 -0.51 -7.08 -0.36 8.46e-12 Schizophrenia; LIHC cis rs9399135 0.967 rs9376075 chr6:135296963 A/G cg22676075 chr6:135203613 NA 0.4 6.47 0.33 3.49e-10 Red blood cell count; LIHC cis rs4665809 1.000 rs4665306 chr2:26319124 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.72 -9.02 -0.44 1.34e-17 Gut microbiome composition (summer); LIHC cis rs709400 0.663 rs3742458 chr14:103950368 A/G cg26031613 chr14:104095156 KLC1 0.72 9.11 0.44 7.32e-18 Body mass index; LIHC trans rs3824488 0.920 rs16909902 chr9:98236202 C/T cg05210886 chr1:245133216 EFCAB2 -0.45 -6.08 -0.31 3.2e-9 Neuroticism; LIHC cis rs4746818 1.000 rs7899844 chr10:70949694 A/G cg11621586 chr10:70884670 VPS26A 0.84 13.55 0.59 8.5e-34 Left atrial antero-posterior diameter; LIHC cis rs6754311 0.509 rs3820794 chr2:136505546 C/T cg07305463 chr2:136567211 LCT 0.34 6.19 0.32 1.77e-9 Mosquito bite size; LIHC cis rs1707322 1.000 rs1768817 chr1:46514534 C/G cg06784218 chr1:46089804 CCDC17 -0.36 -6.5 -0.33 2.8e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs875971 0.522 rs781144 chr7:65440344 C/G cg26939375 chr7:64535504 NA 0.46 6.93 0.35 2.04e-11 Aortic root size; LIHC cis rs1113500 0.933 rs10881497 chr1:108634515 A/G cg06207961 chr1:108661230 NA -0.37 -7.43 -0.37 8.58e-13 Growth-regulated protein alpha levels; LIHC cis rs11190604 1.000 rs74210981 chr10:102287520 C/T cg07080220 chr10:102295463 HIF1AN 0.58 8.18 0.4 5.45e-15 Palmitoleic acid (16:1n-7) levels; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg00219956 chr16:30794205 ZNF629 0.39 6.37 0.33 6.19e-10 Immature fraction of reticulocytes; LIHC cis rs34540877 1.000 rs35256798 chr19:33126329 C/T cg22980127 chr19:33182716 NUDT19 1.03 6.83 0.35 3.95e-11 Red cell distribution width; LIHC cis rs875971 0.628 rs6974355 chr7:65841981 A/G cg11764359 chr7:65958608 NA 0.65 8.84 0.43 5.27e-17 Aortic root size; LIHC cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg17971929 chr21:40555470 PSMG1 0.82 9.83 0.47 2.92e-20 Cognitive function; LIHC cis rs6754311 0.550 rs3213889 chr2:136511575 A/G cg25344623 chr2:136566232 LCT 0.44 8.9 0.43 3.35e-17 Mosquito bite size; LIHC cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.78 0.62 1.38e-38 Prudent dietary pattern; LIHC cis rs4853012 0.838 rs72911122 chr2:74344119 C/G cg20011983 chr2:74347215 NA -0.39 -5.77 -0.3 1.79e-8 Gestational age at birth (maternal effect); LIHC cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg15691649 chr6:25882328 NA -0.54 -6.84 -0.35 3.61e-11 Intelligence (multi-trait analysis); LIHC cis rs1580019 0.568 rs2122633 chr7:32523870 G/T cg06627557 chr7:32535165 LSM5;AVL9 1.06 22.02 0.77 1.47e-67 Cognitive ability; LIHC cis rs36051895 0.589 rs6476948 chr9:5204404 C/T cg02405213 chr9:5042618 JAK2 -0.64 -10.69 -0.5 3.32e-23 Pediatric autoimmune diseases; LIHC cis rs4820294 1.000 rs929039 chr22:38071511 T/C cg10587741 chr22:38071170 LGALS1 0.72 12.36 0.56 2.83e-29 Fat distribution (HIV); LIHC cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg07424592 chr7:64974309 NA 0.79 9.06 0.44 1.04e-17 Diabetic kidney disease; LIHC cis rs6545883 0.895 rs2442029 chr2:61679552 G/T cg15711740 chr2:61764176 XPO1 -0.43 -5.99 -0.31 5.35e-9 Tuberculosis; LIHC cis rs3806843 0.676 rs778591 chr5:140025484 G/A cg16577123 chr5:140027231 NDUFA2;IK -0.42 -5.99 -0.31 5.35e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7772486 0.764 rs7762562 chr6:146158994 T/C cg13319975 chr6:146136371 FBXO30 -0.36 -6.09 -0.31 3e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg12310025 chr6:25882481 NA 0.88 12.41 0.56 1.83e-29 Blood metabolite levels; LIHC cis rs6951245 0.554 rs58210047 chr7:1149381 G/A cg22907277 chr7:1156413 C7orf50 0.86 8.19 0.41 5.14e-15 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1707322 0.752 rs28438704 chr1:46170544 G/A cg03146154 chr1:46216737 IPP 0.6 10.31 0.49 6.92e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9309473 0.904 rs78450880 chr2:73821381 T/G cg20560298 chr2:73613845 ALMS1 -0.54 -6.22 -0.32 1.43e-9 Metabolite levels; LIHC cis rs9359856 0.564 rs36040566 chr6:90372574 A/C cg13799429 chr6:90582589 CASP8AP2 -0.64 -5.83 -0.3 1.29e-8 Bipolar disorder; LIHC cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg24549020 chr5:56110836 MAP3K1 0.5 6.46 0.33 3.61e-10 Initial pursuit acceleration; LIHC cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg20887711 chr4:1340912 KIAA1530 0.81 12.62 0.56 3.05e-30 Longevity; LIHC cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg00656387 chr3:40428638 ENTPD3 -0.51 -8.6 -0.42 2.86e-16 Renal cell carcinoma; LIHC cis rs7264396 0.561 rs57545942 chr20:34183479 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.59 -8.28 -0.41 2.73e-15 Total cholesterol levels; LIHC cis rs7107174 1.000 rs731600 chr11:77963133 A/G cg02023728 chr11:77925099 USP35 0.44 8.56 0.42 3.78e-16 Testicular germ cell tumor; LIHC cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg21747090 chr2:27597821 SNX17 -0.47 -7.03 -0.36 1.09e-11 Total body bone mineral density; LIHC cis rs425277 0.958 rs262652 chr1:2090816 T/C cg24578937 chr1:2090814 PRKCZ 0.5 9.12 0.44 6.5e-18 Height; LIHC cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg23978390 chr7:1156363 C7orf50 0.54 8.45 0.42 8.78e-16 Longevity;Endometriosis; LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg19318889 chr4:1322082 MAEA 0.64 10.24 0.48 1.24e-21 Longevity; LIHC cis rs16866061 0.926 rs17479770 chr2:225335814 A/G cg12698349 chr2:225449008 CUL3 0.73 12.13 0.55 2.09e-28 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs919433 0.963 rs7582736 chr2:198170342 A/G cg10820045 chr2:198174542 NA -0.58 -9.64 -0.46 1.29e-19 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs12497850 0.966 rs6792510 chr3:48723302 G/C cg06212747 chr3:49208901 KLHDC8B 0.48 6.14 0.32 2.23e-9 Parkinson's disease; LIHC cis rs9611565 0.879 rs5758311 chr22:41759375 G/T cg03806693 chr22:41940476 POLR3H -0.49 -6.39 -0.33 5.39e-10 Vitiligo; LIHC cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg11062466 chr8:58055876 NA 0.5 6.9 0.35 2.54e-11 Developmental language disorder (linguistic errors); LIHC cis rs11971779 0.818 rs12056045 chr7:139025430 C/G cg07862535 chr7:139043722 LUC7L2 0.68 11.11 0.51 1.11e-24 Diisocyanate-induced asthma; LIHC cis rs3768617 0.706 rs9943067 chr1:182975102 C/T ch.1.3577855R chr1:183094577 LAMC1 0.5 7.9 0.39 3.98e-14 Fuchs's corneal dystrophy; LIHC cis rs317689 0.690 rs618470 chr12:69672060 A/G cg20891283 chr12:69753455 YEATS4 0.52 7.54 0.38 4.21e-13 Response to diuretic therapy; LIHC cis rs11583043 1.000 rs7541397 chr1:101322866 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.54 -6.8 -0.34 4.79e-11 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2180341 0.920 rs6906717 chr6:127596782 C/A cg27446573 chr6:127587934 RNF146 1.0 15.32 0.64 1.06e-40 Breast cancer; LIHC cis rs8060686 0.516 rs12599238 chr16:68276235 G/A cg05110241 chr16:68378359 PRMT7 -0.62 -6.82 -0.35 4.09e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs7762018 1.000 rs6941766 chr6:170131653 A/G cg19338460 chr6:170058176 WDR27 -0.39 -5.98 -0.31 5.58e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg11952622 chr19:58962976 ZNF324B 0.47 6.98 0.35 1.5e-11 Uric acid clearance; LIHC cis rs769267 0.930 rs2288852 chr19:19605348 T/C cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.37 0.33 6.1e-10 Tonsillectomy; LIHC cis rs35160687 0.623 rs13005014 chr2:86487216 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 0.35 5.75 0.3 2.01e-8 Night sleep phenotypes; LIHC cis rs7707921 0.801 rs862243 chr5:81586829 C/G cg15871215 chr5:81402204 ATG10 0.68 8.24 0.41 3.82e-15 Breast cancer; LIHC cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.88 -12.8 -0.57 6.21e-31 Alzheimer's disease; LIHC trans rs12310956 0.532 rs11052952 chr12:33988048 G/A cg26384229 chr12:38710491 ALG10B 0.55 7.47 0.37 6.8e-13 Morning vs. evening chronotype; LIHC cis rs9814567 0.806 rs6806810 chr3:134323522 G/A cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.8 -0.3 1.53e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg07133347 chr1:107600762 PRMT6 -0.45 -6.72 -0.34 7.59e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4638749 0.677 rs6757761 chr2:108834842 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.02 -0.31 4.52e-9 Blood pressure; LIHC cis rs6540556 0.637 rs12060922 chr1:209904433 G/A cg05527609 chr1:210001259 C1orf107 -0.58 -7.82 -0.39 6.46e-14 Red blood cell count; LIHC cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg13393036 chr8:95962371 TP53INP1 -0.39 -8.83 -0.43 5.69e-17 Type 2 diabetes; LIHC cis rs763121 0.853 rs138712 chr22:39141600 C/T cg06544989 chr22:39130855 UNC84B 0.38 5.91 0.3 8.07e-9 Menopause (age at onset); LIHC cis rs1865760 0.566 rs1800702 chr6:26086463 C/G cg17691542 chr6:26056736 HIST1H1C 0.4 5.78 0.3 1.65e-8 Height; LIHC cis rs17253792 0.545 rs75276278 chr14:56024341 C/T cg01858014 chr14:56050164 KTN1 -0.67 -6.11 -0.31 2.74e-9 Putamen volume; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12465518 chr17:58308936 SCARNA20;USP32 0.42 6.34 0.32 7.28e-10 Longevity; LIHC trans rs9914544 1.000 rs28436199 chr17:18751730 C/T cg04702396 chr17:15466718 FAM18B2 0.43 6.49 0.33 3.07e-10 Educational attainment (years of education); LIHC cis rs7927592 0.871 rs12360903 chr11:68236314 C/A cg01657329 chr11:68192670 LRP5 -0.46 -5.91 -0.3 8.17e-9 Total body bone mineral density; LIHC cis rs7927592 0.913 rs11228287 chr11:68349754 A/G cg01657329 chr11:68192670 LRP5 -0.48 -6.22 -0.32 1.46e-9 Total body bone mineral density; LIHC cis rs2153535 0.623 rs2152346 chr6:8454652 A/G cg07606381 chr6:8435919 SLC35B3 0.81 12.18 0.55 1.4e-28 Motion sickness; LIHC cis rs2766692 1.000 rs2766692 chr14:100684192 C/T cg14866419 chr14:100704911 YY1 0.44 5.99 0.31 5.25e-9 Electroencephalographic traits in alcoholism; LIHC trans rs1499614 0.522 rs13247442 chr7:66188858 T/C cg10756647 chr7:56101905 PSPH 1.05 10.01 0.48 7.62e-21 Gout; LIHC cis rs3806843 0.735 rs801180 chr5:140092903 G/T cg26395211 chr5:140044315 WDR55 0.41 5.99 0.31 5.2e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs2297440 0.530 rs34533955 chr20:62233020 A/C cg06363034 chr20:62225388 GMEB2 -0.44 -7.52 -0.38 4.94e-13 Glioma;Non-glioblastoma glioma;Glioblastoma; LIHC cis rs6500602 0.702 rs1051308 chr16:4560301 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.51 -7.62 -0.38 2.54e-13 Schizophrenia; LIHC cis rs4561483 0.556 rs11570136 chr16:12058832 T/A cg08843971 chr16:11963173 GSPT1 -0.32 -6.39 -0.33 5.5e-10 Testicular germ cell tumor; LIHC cis rs13256369 1.000 rs13266699 chr8:8570313 A/T cg18904891 chr8:8559673 CLDN23 -0.69 -11.23 -0.52 4.12e-25 Obesity-related traits; LIHC cis rs826838 0.620 rs11614695 chr12:39331847 C/T cg26384229 chr12:38710491 ALG10B 0.72 9.38 0.45 9.41e-19 Heart rate; LIHC trans rs11039798 1.000 rs10838918 chr11:48507449 A/G cg15704280 chr7:45808275 SEPT13 0.62 6.44 0.33 4.01e-10 Axial length; LIHC cis rs6951245 0.882 rs11764817 chr7:1064610 T/C cg24642844 chr7:1081250 C7orf50 -0.71 -7.89 -0.39 4.26e-14 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4975709 0.589 rs4975707 chr5:1864028 C/T cg14773178 chr5:1868261 NA 0.26 6.91 0.35 2.42e-11 Cardiovascular disease risk factors; LIHC cis rs17106184 0.892 rs112717424 chr1:51228799 A/G cg07174182 chr1:51127561 FAF1 -0.63 -6.81 -0.35 4.43e-11 Type 2 diabetes; LIHC cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg08888203 chr3:10149979 C3orf24 0.56 6.47 0.33 3.35e-10 Alzheimer's disease; LIHC cis rs2243480 1.000 rs13237037 chr7:65997882 T/C cg05590025 chr7:65112418 INTS4L2 -0.53 -5.75 -0.3 2.01e-8 Diabetic kidney disease; LIHC cis rs1577917 0.876 rs66986937 chr6:86532191 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.19 -0.52 5.38e-25 Response to antipsychotic treatment; LIHC cis rs1003719 0.591 rs13046303 chr21:38551976 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.67 -0.5 3.77e-23 Eye color traits; LIHC trans rs12204683 0.963 rs1485373 chr6:80177371 A/G cg10805819 chr17:6924109 NA -0.53 -6.15 -0.32 2.18e-9 Presence of antiphospholipid antibodies; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27498675 chr19:41945691 ATP5SL 0.49 6.8 0.35 4.57e-11 Pancreatic cancer; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg12662497 chr5:98264283 NA 0.54 6.67 0.34 1.06e-10 Hepatitis; LIHC cis rs11190604 1.000 rs2489043 chr10:102334327 T/C cg07080220 chr10:102295463 HIF1AN 0.55 7.78 0.39 8.4e-14 Palmitoleic acid (16:1n-7) levels; LIHC cis rs116095464 0.558 rs73024831 chr5:257192 A/G cg22857025 chr5:266934 NA -1.51 -18.81 -0.71 1.04e-54 Breast cancer; LIHC cis rs1580019 0.813 rs2044839 chr7:32500805 A/C cg06627557 chr7:32535165 LSM5;AVL9 0.98 16.63 0.67 6.43e-46 Cognitive ability; LIHC cis rs2243480 1.000 rs58669269 chr7:65951953 T/C cg07424592 chr7:64974309 NA 0.81 9.12 0.44 6.81e-18 Diabetic kidney disease; LIHC cis rs10911232 0.507 rs10911199 chr1:182998036 T/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.26 0.48 1.07e-21 Hypertriglyceridemia; LIHC cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.56 8.7 0.43 1.4e-16 Schizophrenia; LIHC cis rs10751667 0.643 rs10751666 chr11:941933 C/T cg10932868 chr11:921992 NA 0.39 7.43 0.37 8.97e-13 Alzheimer's disease (late onset); LIHC cis rs5769765 0.862 rs9616386 chr22:50313179 G/A cg26441486 chr22:50317300 CRELD2 0.36 5.74 0.3 2.1e-8 Schizophrenia; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg16070018 chr6:26224392 HIST1H3E 0.56 7.1 0.36 7.14e-12 Gout;Renal underexcretion gout; LIHC cis rs2380220 0.810 rs877096 chr6:95937046 A/G cg04719120 chr6:96025338 MANEA -0.59 -6.21 -0.32 1.53e-9 Behavioural disinhibition (generation interaction); LIHC cis rs9910055 0.529 rs183462 chr17:42183376 G/C cg19774624 chr17:42201019 HDAC5 0.47 5.96 0.31 6.41e-9 Total body bone mineral density; LIHC cis rs11864453 0.713 rs12708927 chr16:72126165 C/T cg01557791 chr16:72042693 DHODH -0.47 -7.62 -0.38 2.58e-13 Fibrinogen levels; LIHC cis rs6088580 0.634 rs4277599 chr20:33008905 A/G cg08999081 chr20:33150536 PIGU -0.66 -13.41 -0.59 3.1e-33 Glomerular filtration rate (creatinine); LIHC cis rs2404602 1.000 rs12898430 chr15:76874923 G/A cg23625390 chr15:77176239 SCAPER 0.38 6.31 0.32 8.48e-10 Blood metabolite levels; LIHC cis rs7085104 0.727 rs12773892 chr10:104631177 G/A cg15744005 chr10:104629667 AS3MT -0.37 -7.48 -0.38 6.26e-13 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs644799 1.000 rs509720 chr11:95562771 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.85 0.47 2.5e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs8072100 0.875 rs9635762 chr17:45648446 A/C cg08085267 chr17:45401833 C17orf57 0.4 6.05 0.31 3.71e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs2073300 1.000 rs6048835 chr20:23462343 G/C cg12062639 chr20:23401060 NAPB 0.78 9.81 0.47 3.62e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs950169 0.920 rs34672825 chr15:84703470 C/T cg17507749 chr15:85114479 UBE2QP1 0.7 6.87 0.35 3.08e-11 Schizophrenia; LIHC cis rs477895 0.713 rs2282490 chr11:63962152 T/C cg05555928 chr11:63887634 MACROD1 0.51 6.6 0.34 1.59e-10 Mean platelet volume; LIHC cis rs9814567 1.000 rs9813774 chr3:134227100 G/A cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.95 -0.31 6.7e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1577917 1.000 rs12201571 chr6:86609750 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -10.76 -0.5 1.82e-23 Response to antipsychotic treatment; LIHC cis rs1707322 0.717 rs2253862 chr1:46081960 C/T cg03146154 chr1:46216737 IPP -0.56 -9.29 -0.45 1.79e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11123170 0.640 rs2863240 chr2:113970116 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.5 -6.25 -0.32 1.2e-9 Renal function-related traits (BUN); LIHC cis rs8084351 0.512 rs10502967 chr18:50792090 C/T cg24270629 chr18:50823537 DCC -0.5 -7.75 -0.39 1.03e-13 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2073300 0.609 rs2281428 chr20:23400050 C/T cg16736954 chr20:23401023 NAPB 0.71 8.5 0.42 5.81e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9733 0.566 rs11204675 chr1:150570985 A/C cg18016565 chr1:150552671 MCL1 -0.56 -11.34 -0.52 1.65e-25 Tonsillectomy; LIHC cis rs15676 0.783 rs3829057 chr9:131567982 A/G cg13708974 chr9:131466143 PKN3 0.4 5.72 0.3 2.39e-8 Blood metabolite levels; LIHC cis rs6831352 1.000 rs10017466 chr4:100055800 C/T cg13256891 chr4:100009986 ADH5 0.5 5.85 0.3 1.14e-8 Alcohol dependence; LIHC cis rs2228479 0.702 rs11649501 chr16:89850957 A/T cg00800038 chr16:89945340 TCF25 -0.6 -8.65 -0.42 2.09e-16 Skin colour saturation; LIHC cis rs9457247 0.624 rs9457260 chr6:167466665 C/T cg23791538 chr6:167370224 RNASET2 -0.51 -7.75 -0.39 1.07e-13 Crohn's disease; LIHC trans rs801193 1.000 rs11773829 chr7:66141074 G/A cg26939375 chr7:64535504 NA -0.42 -6.7 -0.34 8.79e-11 Aortic root size; LIHC trans rs2727020 0.729 rs1164685 chr11:49293660 G/A cg15704280 chr7:45808275 SEPT13 0.9 16.65 0.67 5.43e-46 Coronary artery disease; LIHC cis rs6500602 1.000 rs6500602 chr16:4497451 T/C cg08645402 chr16:4508243 NA 0.41 7.65 0.38 2e-13 Schizophrenia; LIHC trans rs208520 0.690 rs851468 chr6:66825875 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -8.03 -0.4 1.57e-14 Exhaled nitric oxide output; LIHC cis rs10857712 0.950 rs10857711 chr10:135224059 G/A cg01444801 chr10:135216882 MTG1 -0.64 -9.71 -0.46 7.54e-20 Systemic lupus erythematosus; LIHC cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg12311346 chr5:56204834 C5orf35 -0.56 -7.31 -0.37 1.89e-12 Initial pursuit acceleration; LIHC cis rs7264396 0.747 rs6058291 chr20:34247769 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -11.29 -0.52 2.38e-25 Total cholesterol levels; LIHC cis rs60871478 0.947 rs62432866 chr7:809281 T/G cg27478167 chr7:817139 HEATR2 -0.42 -6.0 -0.31 5.08e-9 Cerebrospinal P-tau181p levels; LIHC cis rs2281845 0.791 rs1325313 chr1:201076167 C/T cg24849736 chr1:201084428 NA -0.34 -6.02 -0.31 4.59e-9 Permanent tooth development; LIHC cis rs6545883 0.860 rs6545847 chr2:61445333 C/T cg14146966 chr2:61757674 XPO1 -0.43 -7.21 -0.36 3.71e-12 Tuberculosis; LIHC cis rs9916302 0.904 rs11078910 chr17:37671269 G/T cg00129232 chr17:37814104 STARD3 -0.42 -6.72 -0.34 7.42e-11 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg05590025 chr7:65112418 INTS4L2 -0.59 -6.58 -0.34 1.81e-10 Diabetic kidney disease; LIHC cis rs597539 0.652 rs646586 chr11:68681653 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.75 -10.68 -0.5 3.53e-23 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs11971779 0.616 rs6949963 chr7:139054325 C/T cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs10464366 0.746 rs6945402 chr7:39145385 A/T cg20302533 chr7:39170763 POU6F2 0.38 6.9 0.35 2.51e-11 IgG glycosylation; LIHC cis rs651907 0.535 rs13084113 chr3:101534039 C/G cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.82 -0.3 1.33e-8 Colorectal cancer; LIHC trans rs61931739 0.500 rs73103774 chr12:34482279 C/T cg26384229 chr12:38710491 ALG10B 0.8 9.83 0.47 3.04e-20 Morning vs. evening chronotype; LIHC trans rs66887589 0.967 rs13104219 chr4:120438174 G/T cg25214090 chr10:38739885 LOC399744 0.39 6.48 0.33 3.26e-10 Diastolic blood pressure; LIHC cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg06238570 chr21:40685208 BRWD1 0.6 7.09 0.36 7.97e-12 Cognitive function; LIHC cis rs3096299 0.967 rs2965827 chr16:89457350 A/C cg01788221 chr16:89496183 ANKRD11 0.38 6.02 0.31 4.45e-9 Multiple myeloma (IgH translocation); LIHC cis rs72781680 1.000 rs17762782 chr2:24126493 A/G cg08917208 chr2:24149416 ATAD2B 0.83 7.69 0.38 1.5700000000000001e-13 Lymphocyte counts; LIHC cis rs9399135 0.967 rs2297340 chr6:135376058 T/C cg22676075 chr6:135203613 NA 0.42 6.67 0.34 1.04e-10 Red blood cell count; LIHC cis rs875971 0.642 rs35526611 chr7:66094008 C/T cg14393609 chr7:65229607 NA -0.37 -5.72 -0.3 2.29e-8 Aortic root size; LIHC cis rs10256972 0.869 rs1007766 chr7:1034903 G/A cg24005260 chr7:1138185 C7orf50 0.39 5.86 0.3 1.08e-8 Longevity;Endometriosis; LIHC cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg02034447 chr16:89574710 SPG7 0.48 7.38 0.37 1.21e-12 Multiple myeloma (IgH translocation); LIHC cis rs9549328 0.800 rs9549616 chr13:113627762 T/G cg18289306 chr13:113640169 MCF2L 0.41 6.39 0.33 5.39e-10 Systolic blood pressure; LIHC trans rs10506458 0.915 rs17687426 chr12:63397900 G/C cg22491629 chr6:157744540 C6orf35 -0.61 -10.91 -0.51 5.45e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs514406 0.825 rs487453 chr1:53271225 T/C cg24675658 chr1:53192096 ZYG11B 0.56 8.79 0.43 7.37e-17 Monocyte count; LIHC cis rs6964587 0.839 rs9656002 chr7:91475007 A/G cg17063962 chr7:91808500 NA -0.96 -17.38 -0.68 5.98e-49 Breast cancer; LIHC cis rs910316 1.000 rs2300601 chr14:75639571 A/G cg08847533 chr14:75593920 NEK9 0.79 15.44 0.64 3.44e-41 Height; LIHC cis rs7772486 0.875 rs1331645 chr6:146398407 C/G cg23711669 chr6:146136114 FBXO30 0.59 9.64 0.46 1.33e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.72 -11.13 -0.52 8.84e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2851682 0.706 rs2727270 chr11:61603237 C/T cg27386326 chr11:61587980 NA 0.58 9.28 0.45 2.03e-18 Gestational age at birth (child effect);Trans fatty acid levels; LIHC cis rs7208859 0.623 rs58089675 chr17:29196764 C/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9818758 0.556 rs9880309 chr3:49304329 G/C cg00383909 chr3:49044727 WDR6 0.76 6.32 0.32 8.01e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7428 0.520 rs7605890 chr2:85559525 A/C cg24342717 chr2:85555507 TGOLN2 -0.72 -9.59 -0.46 1.85e-19 Ear protrusion; LIHC trans rs10506458 0.915 rs2013042 chr12:63394211 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.73 -10.51 -0.49 1.41e-22 Hemostatic factors and hematological phenotypes; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg00745463 chr17:30367425 LRRC37B 0.39 6.04 0.31 4.03e-9 Immature fraction of reticulocytes; LIHC cis rs9902453 0.704 rs2617874 chr17:28085172 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 11.05 0.51 1.81e-24 Coffee consumption (cups per day); LIHC cis rs10779751 0.734 rs910660 chr1:11130643 C/T cg08854313 chr1:11322531 MTOR -0.65 -9.83 -0.47 3.08e-20 Body mass index; LIHC cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg11766577 chr21:47581405 C21orf56 0.45 7.54 0.38 4.32e-13 Testicular germ cell tumor; LIHC trans rs11039798 1.000 rs12225599 chr11:48755868 T/C cg15704280 chr7:45808275 SEPT13 0.63 6.62 0.34 1.36e-10 Axial length; LIHC cis rs1707322 0.721 rs10749856 chr1:46164846 A/T cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs922107 0.738 rs2169065 chr1:90031987 A/G cg15422784 chr1:90023713 LRRC8B -0.48 -7.7 -0.38 1.48e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs2573652 0.755 rs11637186 chr15:100519652 A/G cg09918751 chr15:100517450 ADAMTS17 -0.94 -18.6 -0.71 7.73e-54 Height; LIHC cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg26338869 chr17:61819248 STRADA 0.52 7.08 0.36 8.14e-12 Height; LIHC cis rs9790314 1.000 rs4273380 chr3:160950314 A/G cg03342759 chr3:160939853 NMD3 -0.74 -9.03 -0.44 1.25e-17 Morning vs. evening chronotype; LIHC cis rs7917772 0.503 rs2031601 chr10:104308064 T/G cg22532475 chr10:104410764 TRIM8 -0.3 -5.94 -0.31 6.86e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC trans rs6952808 0.723 rs4721264 chr7:2012997 G/A cg04565464 chr8:145669602 NFKBIL2 0.4 6.55 0.33 2.15e-10 Bipolar disorder and schizophrenia; LIHC trans rs4906332 0.966 rs35799018 chr14:103893475 G/A cg17675199 chr6:35436792 RPL10A 0.31 6.22 0.32 1.49e-9 Coronary artery disease; LIHC cis rs9914988 0.778 rs9907192 chr17:27122426 C/G cg20469991 chr17:27169893 C17orf63 -0.59 -6.94 -0.35 1.97e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg21280719 chr6:42927975 GNMT -0.3 -6.86 -0.35 3.23e-11 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7927771 0.832 rs6485753 chr11:47410200 C/T cg20307385 chr11:47447363 PSMC3 0.45 5.86 0.3 1.1e-8 Subjective well-being; LIHC cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg18252515 chr7:66147081 NA -1.24 -16.36 -0.66 7.56e-45 Diabetic kidney disease; LIHC cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg06697600 chr4:7070879 GRPEL1 -0.64 -10.27 -0.49 9.8e-22 Monocyte percentage of white cells; LIHC cis rs72781680 1.000 rs72796388 chr2:24171509 A/C cg08917208 chr2:24149416 ATAD2B 0.86 7.99 0.4 2.06e-14 Lymphocyte counts; LIHC cis rs9948 0.867 rs17119598 chr2:97486315 A/G cg01990225 chr2:97406019 LMAN2L 0.66 6.32 0.32 8.37e-10 Erectile dysfunction and prostate cancer treatment; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00692763 chr18:47088373 LIPG 0.45 6.6 0.34 1.54e-10 Pancreatic cancer; LIHC cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg08496016 chr9:99181722 ZNF367 0.39 6.5 0.33 2.78e-10 Cognitive function; LIHC cis rs7572733 0.555 rs7600269 chr2:198923468 C/G cg03934865 chr2:198174659 NA 0.44 6.16 0.32 2.06e-9 Dermatomyositis; LIHC cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg11062466 chr8:58055876 NA 0.5 6.45 0.33 3.92e-10 Developmental language disorder (linguistic errors); LIHC trans rs2270927 0.834 rs4496693 chr5:75576729 T/C cg13563193 chr19:33072644 PDCD5 0.98 10.23 0.48 1.3e-21 Mean corpuscular volume; LIHC cis rs2108225 0.934 rs2283045 chr7:107440714 G/A cg18560240 chr7:107437656 SLC26A3 -0.46 -7.22 -0.36 3.3e-12 Ulcerative colitis; LIHC trans rs7618501 1.000 rs11130218 chr3:49752372 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs477895 0.838 rs11605738 chr11:64013406 G/A cg18225595 chr11:63971243 STIP1 0.64 7.82 0.39 6.43e-14 Mean platelet volume; LIHC cis rs77861329 1.000 rs9882775 chr3:52149649 C/T cg08692210 chr3:52188851 WDR51A 0.82 7.35 0.37 1.52e-12 Macrophage inflammatory protein 1b levels; LIHC cis rs2857078 0.745 rs4793085 chr17:42320732 A/C cg19774624 chr17:42201019 HDAC5 0.58 8.06 0.4 1.32e-14 Red cell distribution width;Reticulocyte count; LIHC cis rs113507773 1 rs113507773 chr6:26255739 G/A cg16070018 chr6:26224392 HIST1H3E 0.67 7.39 0.37 1.15e-12 Iron status biomarkers (transferrin saturation);Iron status biomarkers (iron levels); LIHC cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg10755058 chr3:40428713 ENTPD3 -0.4 -6.92 -0.35 2.2e-11 Renal cell carcinoma; LIHC cis rs11190604 0.790 rs11190535 chr10:102197441 A/T cg07080220 chr10:102295463 HIF1AN 0.48 6.92 0.35 2.27e-11 Palmitoleic acid (16:1n-7) levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg22837342 chr14:23755408 HOMEZ -0.54 -6.42 -0.33 4.65e-10 Systolic blood pressure; LIHC cis rs710216 0.912 rs11537640 chr1:43424519 T/G cg03128534 chr1:43423976 SLC2A1 0.48 5.87 0.3 1.03e-8 Red cell distribution width; LIHC cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg12463550 chr7:65579703 CRCP -0.67 -6.86 -0.35 3.29e-11 Diabetic kidney disease; LIHC cis rs950169 0.922 rs4842941 chr15:84831312 G/C cg03959625 chr15:84868606 LOC388152 -0.44 -6.47 -0.33 3.31e-10 Schizophrenia; LIHC cis rs11623869 0.711 rs2403173 chr14:103909289 T/C cg26031613 chr14:104095156 KLC1 0.72 9.71 0.46 7.42e-20 Bone mineral density; LIHC cis rs7903847 0.619 rs10786336 chr10:99134953 A/C cg06359132 chr10:99160096 RRP12 -0.42 -6.6 -0.34 1.57e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9814567 0.964 rs9820425 chr3:134223018 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.42 -6.06 -0.31 3.65e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg14004847 chr7:1930337 MAD1L1 -0.48 -6.98 -0.35 1.52e-11 Bipolar disorder and schizophrenia; LIHC cis rs7584330 0.554 rs74001386 chr2:238425333 T/A cg08992911 chr2:238395768 MLPH 0.49 6.0 0.31 5.06e-9 Prostate cancer; LIHC cis rs6459788 0.529 rs34237037 chr7:157255078 G/A cg06271696 chr7:157225062 NA -0.47 -7.34 -0.37 1.57e-12 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs950776 1.000 rs950776 chr15:78926018 A/G cg06917634 chr15:78832804 PSMA4 0.5 6.16 0.32 1.99e-9 Sudden cardiac arrest; LIHC trans rs3904778 1.000 rs4961736 chr9:16694210 A/C cg03981286 chr3:122863126 PDIA5 -0.36 -6.06 -0.31 3.55e-9 Adolescent idiopathic scoliosis; LIHC cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg18404041 chr3:52824283 ITIH1 -0.57 -9.51 -0.46 3.48e-19 Intelligence (multi-trait analysis); LIHC cis rs950169 0.840 rs12905223 chr15:85114268 T/C cg17507749 chr15:85114479 UBE2QP1 0.76 8.71 0.43 1.33e-16 Schizophrenia; LIHC cis rs36051895 0.559 rs10815172 chr9:5212254 T/A cg02405213 chr9:5042618 JAK2 -0.61 -10.44 -0.49 2.41e-22 Pediatric autoimmune diseases; LIHC cis rs6952809 0.532 rs6956223 chr7:2431331 T/C cg23289794 chr7:2394357 EIF3B -0.72 -7.04 -0.36 1.08e-11 Multiple sclerosis; LIHC cis rs1451375 0.617 rs10276473 chr7:50612997 A/C cg14593290 chr7:50529359 DDC -0.6 -9.56 -0.46 2.44e-19 Malaria; LIHC cis rs9916302 0.808 rs12947281 chr17:37652210 G/T cg07936489 chr17:37558343 FBXL20 -0.85 -13.69 -0.6 2.49e-34 Glomerular filtration rate (creatinine); LIHC cis rs10774547 0.965 rs11065109 chr12:120863914 T/C cg12219531 chr12:120966889 COQ5 0.35 5.86 0.3 1.08e-8 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); LIHC cis rs2274273 0.773 rs28430823 chr14:55816560 C/G cg01864836 chr14:55583639 NA -0.37 -6.59 -0.34 1.66e-10 Protein biomarker; LIHC cis rs875971 0.862 rs801204 chr7:66022921 T/C cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.28e-34 Aortic root size; LIHC cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg06481639 chr22:41940642 POLR3H -0.62 -5.96 -0.31 6.33e-9 Vitiligo; LIHC cis rs1005277 0.579 rs2505198 chr10:38393183 A/C cg03665457 chr10:38645376 HSD17B7P2 -0.39 -5.77 -0.3 1.81e-8 Extrinsic epigenetic age acceleration; LIHC cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg25072359 chr17:41440525 NA 0.38 6.14 0.32 2.23e-9 Menopause (age at onset); LIHC trans rs1814175 0.558 rs5025146 chr11:49795724 C/G cg03929089 chr4:120376271 NA -0.84 -15.93 -0.65 3.87e-43 Height; LIHC cis rs1577917 0.958 rs6900436 chr6:86506288 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.43 -7.93 -0.39 3.14e-14 Response to antipsychotic treatment; LIHC cis rs780096 0.505 rs12475426 chr2:27599132 G/A cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.07 -0.31 3.49e-9 Total body bone mineral density; LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs921968 0.541 rs3821031 chr2:219295249 C/T cg02176678 chr2:219576539 TTLL4 -0.57 -7.8 -0.39 7.65e-14 Mean corpuscular hemoglobin concentration; LIHC trans rs4942242 0.663 rs34595450 chr13:44221245 A/G cg19169023 chr15:41853346 TYRO3 -0.54 -7.54 -0.38 4.16e-13 Response to tocilizumab in rheumatoid arthritis; LIHC cis rs6121246 0.954 rs6060992 chr20:30431255 G/T cg13852791 chr20:30311386 BCL2L1 0.86 9.05 0.44 1.12e-17 Mean corpuscular hemoglobin; LIHC cis rs2257205 0.667 rs11653526 chr17:56761417 G/A cg12560992 chr17:57184187 TRIM37 0.73 7.72 0.39 1.32e-13 Pancreatic cancer; LIHC cis rs225245 0.782 rs321617 chr17:33915246 A/G cg05299278 chr17:33885742 SLFN14 0.22 5.97 0.31 6.05e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg13395646 chr4:1353034 KIAA1530 0.64 9.12 0.44 6.45e-18 Obesity-related traits; LIHC cis rs6545883 0.929 rs7606167 chr2:61742654 C/G cg15711740 chr2:61764176 XPO1 -0.44 -6.21 -0.32 1.52e-9 Tuberculosis; LIHC cis rs875971 0.767 rs61348003 chr7:66005934 C/T cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.34e-9 Aortic root size; LIHC cis rs10792665 0.724 rs1904429 chr11:82721585 C/T cg24227371 chr11:82718527 RAB30 -0.38 -9.3 -0.45 1.69e-18 Obesity-related traits; LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg11235426 chr6:292522 DUSP22 -0.53 -7.06 -0.36 9.64e-12 Menopause (age at onset); LIHC cis rs9948 1.000 rs59244622 chr2:97501632 C/T cg01990225 chr2:97406019 LMAN2L -0.62 -5.8 -0.3 1.51e-8 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg22168489 chr12:122356033 WDR66 0.4 6.06 0.31 3.52e-9 Mean corpuscular volume; LIHC cis rs6977660 1.000 rs1468288 chr7:19810580 C/G cg07541023 chr7:19748670 TWISTNB 0.4 5.77 0.3 1.78e-8 Thyroid stimulating hormone; LIHC cis rs2153535 0.580 rs5001322 chr6:8451608 A/G cg23788917 chr6:8435910 SLC35B3 0.6 8.53 0.42 4.89e-16 Motion sickness; LIHC cis rs2032447 0.839 rs6901039 chr6:26000885 A/C cg15691649 chr6:25882328 NA -0.48 -6.38 -0.33 5.66e-10 Intelligence (multi-trait analysis); LIHC cis rs9326248 1.000 rs664971 chr11:117070857 A/G cg15534755 chr11:117069859 TAGLN -0.4 -6.81 -0.35 4.5e-11 Blood protein levels; LIHC cis rs17685 0.775 rs11761172 chr7:75761547 C/T cg01364799 chr7:75623366 TMEM120A -0.5 -7.62 -0.38 2.55e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1008375 1.000 rs4642241 chr4:17617111 T/C cg02297831 chr4:17616191 MED28 0.5 7.76 0.39 9.61e-14 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9916302 0.861 rs632202 chr17:37453294 C/A cg00129232 chr17:37814104 STARD3 0.38 6.13 0.31 2.36e-9 Glomerular filtration rate (creatinine); LIHC cis rs10752881 1.000 rs10911191 chr1:182984524 A/G ch.1.3577855R chr1:183094577 LAMC1 0.54 9.45 0.46 5.41e-19 Colorectal cancer; LIHC cis rs79387448 0.745 rs7582378 chr2:103162263 C/A cg09003973 chr2:102972529 NA 0.88 7.61 0.38 2.62e-13 Gut microbiota (bacterial taxa); LIHC cis rs7666738 0.830 rs13125930 chr4:98654695 G/A cg05340658 chr4:99064831 C4orf37 0.63 11.07 0.51 1.56e-24 Colonoscopy-negative controls vs population controls; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21790971 chr4:54244117 FIP1L1 0.47 6.48 0.33 3.14e-10 Pancreatic cancer; LIHC cis rs7937682 1.000 rs11213973 chr11:111538903 A/T cg09085632 chr11:111637200 PPP2R1B -0.99 -12.56 -0.56 4.97e-30 Primary sclerosing cholangitis; LIHC cis rs17539620 0.624 rs117591255 chr6:154839118 G/A cg20019720 chr6:154832845 CNKSR3 0.4 5.86 0.3 1.11e-8 Lipoprotein (a) levels; LIHC trans rs11935423 0.735 rs7693979 chr4:100464565 A/T cg05278271 chr19:7554137 PEX11G 0.44 6.15 0.32 2.2e-9 Gut microbiome composition (summer); LIHC cis rs425277 0.565 rs2480711 chr1:2111376 A/G cg03732007 chr1:2071316 PRKCZ 0.34 5.72 0.3 2.34e-8 Height; LIHC cis rs950169 0.723 rs17589320 chr15:84919996 C/A cg17507749 chr15:85114479 UBE2QP1 0.75 8.92 0.43 2.89e-17 Schizophrenia; LIHC cis rs752092 1.000 rs8033360 chr15:101778710 C/A cg19997662 chr15:101784653 CHSY1 -0.43 -5.77 -0.3 1.79e-8 Corneal structure; LIHC cis rs9399137 0.507 rs4896118 chr6:135276065 A/G cg24558204 chr6:135376177 HBS1L -0.55 -9.1 -0.44 7.87e-18 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs861318 0.640 rs2852696 chr1:159015984 G/A cg11003133 chr1:159046391 AIM2 0.32 6.24 0.32 1.32e-9 Obesity-related traits; LIHC trans rs1005277 0.579 rs116912400 chr10:38479207 G/T cg23533926 chr12:111358616 MYL2 -0.32 -6.12 -0.31 2.61e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2204008 0.837 rs11514225 chr12:38076270 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.66 0.5 4.11e-23 Bladder cancer; LIHC cis rs7703051 0.520 rs13354746 chr5:74619132 C/T cg07671805 chr5:74907694 NA 0.47 6.3 0.32 8.93e-10 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs4808199 0.948 rs11085261 chr19:19462606 G/A cg03709012 chr19:19516395 GATAD2A 0.99 15.8 0.65 1.29e-42 Nonalcoholic fatty liver disease; LIHC cis rs727505 1.000 rs28622327 chr7:124526213 C/T cg23710748 chr7:124431027 NA -0.32 -5.78 -0.3 1.66e-8 Lewy body disease; LIHC cis rs11628318 0.853 rs4906226 chr14:103027359 C/T cg12046867 chr14:103022105 NA -0.57 -8.37 -0.41 1.45e-15 Platelet count; LIHC cis rs9916302 0.851 rs677888 chr17:37461018 T/G cg07936489 chr17:37558343 FBXL20 0.78 11.99 0.54 6.93e-28 Glomerular filtration rate (creatinine); LIHC cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg21782813 chr7:2030301 MAD1L1 0.42 6.83 0.35 3.91e-11 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg25894440 chr7:65020034 NA 0.52 6.05 0.31 3.73e-9 Diabetic kidney disease; LIHC cis rs10751667 1.000 rs11246359 chr11:967943 T/C cg06064525 chr11:970664 AP2A2 -0.5 -12.47 -0.56 1.14e-29 Alzheimer's disease (late onset); LIHC cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg12310025 chr6:25882481 NA 0.49 6.29 0.32 9.81e-10 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.889 rs2000909 chr6:127711173 G/A cg27446573 chr6:127587934 RNF146 0.82 13.33 0.58 6e-33 Breast cancer; LIHC cis rs1881396 0.947 rs8731 chr2:27873326 C/G cg27432699 chr2:27873401 GPN1 0.51 7.87 0.39 4.73e-14 Nonalcoholic fatty liver disease; LIHC cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg00825309 chr19:58991885 ZNF446 -0.56 -8.67 -0.42 1.76e-16 Uric acid clearance; LIHC cis rs6938 0.596 rs11072511 chr15:75159433 A/G cg14664628 chr15:75095509 CSK -0.51 -7.21 -0.36 3.7e-12 Breast cancer; LIHC cis rs7927771 0.931 rs4752801 chr11:47907641 A/G cg20135002 chr11:47629003 NA -0.5 -8.45 -0.42 8.32e-16 Subjective well-being; LIHC cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg27297192 chr10:134578999 INPP5A 0.56 7.71 0.38 1.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs13382862 1.000 rs13382862 chr2:20882449 A/G cg07021052 chr2:20871279 NA -0.39 -6.98 -0.35 1.52e-11 Abdominal aortic aneurysm; LIHC cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg16049864 chr8:95962084 TP53INP1 -0.67 -13.15 -0.58 2.9e-32 Type 2 diabetes; LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg06873352 chr17:61820015 STRADA 0.74 13.29 0.58 8.87e-33 Prudent dietary pattern; LIHC cis rs7772486 0.790 rs7742333 chr6:146159029 A/G cg13319975 chr6:146136371 FBXO30 0.36 5.9 0.3 8.6e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.526 rs11127013 chr2:27692973 A/G cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.95 -0.31 6.51e-9 Total body bone mineral density; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg19487717 chr11:70263216 CTTN 0.45 6.75 0.34 6.5e-11 Bilirubin levels; LIHC cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg14004847 chr7:1930337 MAD1L1 -0.48 -6.86 -0.35 3.21e-11 Bipolar disorder and schizophrenia; LIHC cis rs922107 0.738 rs922106 chr1:90025519 C/A cg15422784 chr1:90023713 LRRC8B -0.48 -7.75 -0.39 1.05e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs1865760 1.000 rs9393675 chr6:25930116 G/A cg03517284 chr6:25882590 NA -0.39 -5.81 -0.3 1.44e-8 Height; LIHC cis rs7772486 0.846 rs1854901 chr6:146325685 T/C cg23711669 chr6:146136114 FBXO30 0.6 10.46 0.49 2.08e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs12744310 0.945 rs34961305 chr1:41765944 A/G cg03962019 chr1:41807865 NA 0.38 6.22 0.32 1.46e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs561341 0.883 rs1034627 chr17:30219569 C/T cg13647721 chr17:30228624 UTP6 0.77 7.99 0.4 2.02e-14 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg18481087 chr3:160474064 PPM1L -0.44 -6.04 -0.31 4.1e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs67981189 0.593 rs1468470 chr14:71555531 C/T cg15816911 chr14:71606274 NA 0.43 6.89 0.35 2.65e-11 Schizophrenia; LIHC cis rs4555082 0.834 rs2816652 chr14:105712493 C/T cg13114125 chr14:105738426 BRF1 -0.78 -10.1 -0.48 3.66e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs780096 0.546 rs6547626 chr2:27646770 C/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.45 -6.97 -0.35 1.59e-11 Total body bone mineral density; LIHC cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg05185784 chr16:90016020 DEF8 -0.43 -5.87 -0.3 1.01e-8 Skin colour saturation; LIHC cis rs920590 0.758 rs1817836 chr8:19664852 T/C cg01411142 chr8:19674711 INTS10 0.5 7.72 0.39 1.28e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs28735056 1.000 rs28865701 chr18:77620911 A/G cg20368463 chr18:77673604 PQLC1 -0.36 -6.52 -0.33 2.58e-10 Schizophrenia; LIHC cis rs7927592 0.913 rs67005337 chr11:68307758 A/C cg16797656 chr11:68205561 LRP5 0.51 8.01 0.4 1.84e-14 Total body bone mineral density; LIHC cis rs2235642 0.750 rs2974845 chr16:1648162 T/C cg03034668 chr16:1723424 CRAMP1L -0.37 -6.51 -0.33 2.64e-10 Coronary artery disease; LIHC cis rs2243480 1.000 rs778679 chr7:65840911 A/G cg18252515 chr7:66147081 NA -1.29 -17.55 -0.69 1.32e-49 Diabetic kidney disease; LIHC cis rs7618501 0.933 rs1128535 chr3:49866392 C/T cg21467203 chr3:49911342 NA -0.4 -6.98 -0.35 1.56e-11 Intelligence (multi-trait analysis); LIHC trans rs9956878 0.555 rs8085188 chr18:73544676 A/G cg14307892 chr10:124767941 IKZF5;ACADSB -0.45 -6.28 -0.32 1.06e-9 Obesity-related traits; LIHC cis rs929354 0.742 rs6459734 chr7:156935454 A/G cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs9311474 0.581 rs13621 chr3:52558133 T/C cg10802521 chr3:52805072 NEK4 -0.39 -6.54 -0.33 2.27e-10 Electroencephalogram traits; LIHC cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg22903471 chr2:27725779 GCKR -0.48 -8.39 -0.41 1.28e-15 Menopause (age at onset); LIHC cis rs655641 1.000 rs2508688 chr11:85692342 A/C cg09030501 chr11:85779252 PICALM -0.52 -6.38 -0.33 5.85e-10 Platelet count; LIHC cis rs8005677 1.000 rs4981446 chr14:23381413 A/G cg25600027 chr14:23388339 RBM23 -0.42 -6.09 -0.31 2.99e-9 Cognitive ability (multi-trait analysis); LIHC cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg09455208 chr3:40491958 NA 0.39 7.79 0.39 8.31e-14 Renal cell carcinoma; LIHC cis rs477692 0.699 rs576175 chr10:131386408 A/T cg19680672 chr10:131412579 MGMT -0.4 -6.03 -0.31 4.3e-9 Response to temozolomide; LIHC cis rs1707322 0.686 rs2991979 chr1:46055858 A/G cg03146154 chr1:46216737 IPP -0.55 -8.88 -0.43 3.91e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg06420487 chr17:61919686 SMARCD2 0.45 6.09 0.31 2.99e-9 Height; LIHC cis rs910316 0.935 rs2268620 chr14:75640403 G/A cg08847533 chr14:75593920 NEK9 -0.87 -18.95 -0.72 3.04e-55 Height; LIHC cis rs2832191 0.740 rs2853830 chr21:30416824 A/G cg24692254 chr21:30365293 RNF160 0.85 15.13 0.63 5.75e-40 Dental caries; LIHC cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg17971929 chr21:40555470 PSMG1 -0.41 -6.22 -0.32 1.45e-9 Menarche (age at onset); LIHC cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.15 17.72 0.69 2.72e-50 Gut microbiome composition (summer); LIHC cis rs2016586 0.832 rs5999963 chr22:36105832 T/A cg26342177 chr22:36113512 APOL5 -0.37 -6.38 -0.33 5.83e-10 Body mass index; LIHC trans rs1866631 1.000 rs1866631 chr2:174075761 G/A cg11425656 chr7:44791211 ZMIZ2 0.37 6.27 0.32 1.09e-9 Lung cancer in ever smokers; LIHC cis rs8077889 0.700 rs28571770 chr17:41904066 A/T cg26893861 chr17:41843967 DUSP3 0.93 10.72 0.5 2.51e-23 Triglycerides; LIHC cis rs56011263 0.687 rs11734460 chr4:705074 C/T cg17689763 chr4:710664 PCGF3 -0.73 -10.54 -0.5 1.15e-22 White blood cell count; LIHC trans rs3960554 0.529 rs6465049 chr7:75874489 A/G cg19862616 chr7:65841803 NCRNA00174 0.61 9.4 0.45 7.81e-19 Eotaxin levels; LIHC cis rs801193 0.935 rs3800820 chr7:66147178 C/T cg14393609 chr7:65229607 NA -0.37 -5.88 -0.3 1e-8 Aortic root size; LIHC cis rs655641 1.000 rs2077815 chr11:85672383 G/A cg09030501 chr11:85779252 PICALM -0.49 -6.04 -0.31 4.07e-9 Platelet count; LIHC cis rs7826238 0.566 rs2945886 chr8:8148270 C/G cg08975724 chr8:8085496 FLJ10661 0.43 7.29 0.37 2.11e-12 Systolic blood pressure; LIHC cis rs743757 1.000 rs2236984 chr3:50495487 A/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.51 7.95 0.4 2.66e-14 Diastolic blood pressure; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg05484376 chr2:27715224 FNDC4 0.38 6.46 0.33 3.65e-10 Total body bone mineral density; LIHC cis rs67311347 0.668 rs73071710 chr3:40288587 A/G cg10755058 chr3:40428713 ENTPD3 0.37 6.06 0.31 3.63e-9 Renal cell carcinoma; LIHC cis rs611744 0.967 rs628340 chr8:109189425 A/G cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs9486719 1.000 rs2499809 chr6:96870110 C/T cg06623918 chr6:96969491 KIAA0776 0.74 7.29 0.37 2.22e-12 Migraine;Coronary artery disease; LIHC cis rs7945705 0.869 rs2742471 chr11:9003953 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.43 -7.24 -0.36 2.94e-12 Hemoglobin concentration; LIHC cis rs7106204 0.748 rs11827778 chr11:24211321 G/A ch.11.24196551F chr11:24239977 NA 0.78 10.32 0.49 6.52e-22 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4474465 0.790 rs7106931 chr11:78229612 A/G cg27205649 chr11:78285834 NARS2 0.41 6.08 0.31 3.13e-9 Alzheimer's disease (survival time); LIHC cis rs60871478 0.636 rs56393680 chr7:885696 A/G cg05535760 chr7:792225 HEATR2 -0.8 -6.29 -0.32 9.77e-10 Cerebrospinal P-tau181p levels; LIHC cis rs7534824 0.625 rs61780287 chr1:101382744 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.64 6.5 0.33 2.76e-10 Refractive astigmatism; LIHC cis rs10861342 0.892 rs11112366 chr12:105486108 G/A cg23923672 chr12:105501055 KIAA1033 0.64 7.47 0.37 6.71e-13 IgG glycosylation; LIHC cis rs7772486 0.790 rs80050589 chr6:146230454 T/C cg05347473 chr6:146136440 FBXO30 -0.38 -6.05 -0.31 3.73e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4908768 0.501 rs6577499 chr1:8612104 C/G cg20416874 chr1:8611966 RERE 0.7 15.11 0.63 6.87e-40 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs778371 0.834 rs778363 chr2:233778896 A/G cg08000102 chr2:233561755 GIGYF2 -0.79 -8.21 -0.41 4.43e-15 Schizophrenia; LIHC cis rs6831352 0.918 rs1042364 chr4:100045574 T/C cg12011299 chr4:100065546 ADH4 0.61 10.36 0.49 4.77e-22 Alcohol dependence; LIHC cis rs589448 0.902 rs315134 chr12:69762713 G/A cg20891283 chr12:69753455 YEATS4 0.95 22.43 0.77 3.55e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs763121 0.776 rs4820346 chr22:39125074 C/G cg06022373 chr22:39101656 GTPBP1 -0.63 -10.63 -0.5 5.37e-23 Menopause (age at onset); LIHC cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs68170813 0.559 rs60255281 chr7:106963913 C/T cg02696742 chr7:106810147 HBP1 -0.5 -5.77 -0.3 1.75e-8 Coronary artery disease; LIHC cis rs12908161 1.000 rs12908549 chr15:85322351 C/G cg12863693 chr15:85201151 NMB 0.44 6.34 0.32 7.18e-10 Schizophrenia; LIHC cis rs6684514 1.000 rs67034206 chr1:156270260 C/T cg16558208 chr1:156270281 VHLL 0.54 10.19 0.48 1.79e-21 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs9818758 0.607 rs35108630 chr3:49088356 T/A cg07636037 chr3:49044803 WDR6 -0.84 -8.52 -0.42 5.33e-16 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs9911578 0.967 rs1267542 chr17:56654690 T/C cg12560992 chr17:57184187 TRIM37 -0.97 -17.74 -0.69 2.19e-50 Intelligence (multi-trait analysis); LIHC cis rs9311474 0.575 rs4434138 chr3:52556890 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.42 5.72 0.3 2.33e-8 Electroencephalogram traits; LIHC cis rs6061231 0.724 rs1570027 chr20:60968596 A/G cg22601191 chr20:60968625 CABLES2 0.45 5.79 0.3 1.59e-8 Colorectal cancer; LIHC cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg00475322 chr7:917719 C7orf20 -0.41 -7.0 -0.35 1.33e-11 Perceived unattractiveness to mosquitoes; LIHC trans rs9900280 1.000 rs8081267 chr17:27763910 G/T cg16717988 chr16:89715857 CHMP1A 0.58 6.25 0.32 1.25e-9 Mean platelet volume; LIHC cis rs4819052 0.807 rs4819047 chr21:46665139 C/T cg11663144 chr21:46675770 NA -0.32 -5.88 -0.3 9.53e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs36051895 0.589 rs16922779 chr9:5200127 G/A cg02405213 chr9:5042618 JAK2 -0.65 -10.93 -0.51 4.55e-24 Pediatric autoimmune diseases; LIHC cis rs8058578 1.000 rs13338946 chr16:30700858 T/C cg02466173 chr16:30829666 NA -0.46 -7.25 -0.37 2.77e-12 Multiple myeloma; LIHC cis rs7927592 0.913 rs7123564 chr11:68362164 C/T cg16797656 chr11:68205561 LRP5 0.5 7.78 0.39 8.69e-14 Total body bone mineral density; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11296937 chr11:64084966 PRDX5;TRMT112 -0.39 -6.03 -0.31 4.15e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg05368731 chr17:41323189 NBR1 0.72 12.37 0.56 2.77e-29 Menopause (age at onset); LIHC cis rs716804 0.740 rs4597056 chr11:10290923 C/T cg01453529 chr11:10209919 SBF2 -0.29 -5.89 -0.3 9.09e-9 Neuroticism; LIHC cis rs2710642 0.962 rs1828398 chr2:63034870 A/G cg17519650 chr2:63277830 OTX1 -0.43 -6.75 -0.34 6.29e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs10419226 0.625 rs12974777 chr19:18765663 C/T cg16673477 chr19:18812017 CRTC1 -0.32 -5.77 -0.3 1.75e-8 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs2991971 0.967 rs937291 chr1:45957039 G/T cg15605315 chr1:45957053 TESK2 0.49 6.89 0.35 2.65e-11 High light scatter reticulocyte count; LIHC cis rs4951018 0.526 rs4245718 chr1:205652472 G/A cg17723122 chr1:205641542 SLC45A3 0.42 6.32 0.32 8.38e-10 Prostate-specific antigen levels; LIHC cis rs11945232 1.000 rs6854710 chr4:88334640 A/G cg23841344 chr4:88312519 HSD17B11 -0.57 -7.8 -0.39 7.44e-14 Intelligence (multi-trait analysis); LIHC cis rs875971 0.545 rs73378304 chr7:65640747 G/A cg11764359 chr7:65958608 NA 0.54 7.64 0.38 2.28e-13 Aortic root size; LIHC cis rs12368653 0.582 rs2307095 chr12:58026001 G/A cg12615879 chr12:58013172 SLC26A10 0.36 6.9 0.35 2.58e-11 Multiple sclerosis; LIHC cis rs9814567 0.806 rs1880374 chr3:134322113 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.44 -0.45 5.75e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8103278 0.701 rs116959973 chr19:46252333 A/T cg11657440 chr19:46296263 DMWD -0.53 -7.87 -0.39 4.76e-14 Coronary artery disease; LIHC cis rs2019216 0.903 rs1817415 chr17:21893338 C/G cg22648282 chr17:21454238 C17orf51 -0.34 -5.82 -0.3 1.33e-8 Pelvic organ prolapse; LIHC cis rs6545883 0.894 rs12997538 chr2:61564249 A/C cg14146966 chr2:61757674 XPO1 -0.43 -7.12 -0.36 6.29e-12 Tuberculosis; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg04571327 chr6:97345972 NDUFAF4 0.41 6.2 0.32 1.67e-9 Migraine with aura; LIHC cis rs6977660 0.714 rs1468287 chr7:19784210 T/A cg07541023 chr7:19748670 TWISTNB 0.5 7.23 0.36 3.08e-12 Thyroid stimulating hormone; LIHC cis rs910316 0.726 rs61979167 chr14:75663610 C/T cg11812906 chr14:75593930 NEK9 -0.68 -12.48 -0.56 1e-29 Height; LIHC cis rs6754311 0.731 rs12615624 chr2:136721603 A/G cg25344623 chr2:136566232 LCT -0.36 -7.33 -0.37 1.71e-12 Mosquito bite size; LIHC cis rs10744422 0.800 rs839363 chr12:123276924 C/T cg22842854 chr12:123319900 HIP1R -0.65 -8.08 -0.4 1.14e-14 Schizophrenia; LIHC cis rs10464366 0.544 rs4355688 chr7:39158402 C/T cg15212455 chr7:39170539 POU6F2 0.48 8.49 0.42 6.22e-16 IgG glycosylation; LIHC trans rs6598955 0.671 rs11247908 chr1:26638222 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.74 -7.84 -0.39 5.84e-14 Obesity-related traits; LIHC cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg16325326 chr1:53192061 ZYG11B -0.51 -8.76 -0.43 9.25e-17 Monocyte count; LIHC cis rs611744 0.967 rs636399 chr8:109235569 G/A cg21045802 chr8:109455806 TTC35 0.51 8.71 0.43 1.31e-16 Dupuytren's disease; LIHC cis rs16958440 0.867 rs12326412 chr18:44683594 A/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs11212260 0.655 rs11212210 chr11:107282069 T/C cg25435332 chr11:107328525 CWF19L2 0.81 8.62 0.42 2.61e-16 IgG glycosylation; LIHC cis rs7075426 0.583 rs4934208 chr10:88199488 C/T cg07322936 chr10:88137208 NA 0.49 6.23 0.32 1.37e-9 Migraine without aura; LIHC trans rs13063635 0.915 rs77902290 chr3:45976662 C/T cg21656520 chr2:210867290 RPE 0.86 6.09 0.31 3.09e-9 Eosinophil percentage of granulocytes; LIHC cis rs7927592 0.956 rs7104877 chr11:68377602 G/T cg16797656 chr11:68205561 LRP5 -0.53 -8.55 -0.42 4.08e-16 Total body bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05157912 chr14:75894395 JDP2 -0.45 -6.41 -0.33 4.94e-10 Cognitive function; LIHC cis rs1639906 0.895 rs62443039 chr7:2209354 C/T cg02951883 chr7:2050386 MAD1L1 0.54 7.38 0.37 1.2e-12 Colonoscopy-negative controls vs population controls; LIHC cis rs965469 0.779 rs6037534 chr20:3269832 G/A cg25506879 chr20:3388711 C20orf194 -0.53 -6.5 -0.33 2.85e-10 IFN-related cytopenia; LIHC cis rs780096 0.506 rs1262430 chr2:27673798 T/C cg22903471 chr2:27725779 GCKR -0.5 -8.61 -0.42 2.7e-16 Total body bone mineral density; LIHC cis rs7909074 0.509 rs2026427 chr10:45389704 T/C cg05187965 chr10:45406764 TMEM72 -0.26 -6.3 -0.32 9.42e-10 Mean corpuscular volume; LIHC cis rs17401966 1.000 rs12755094 chr1:10305711 T/C cg15208524 chr1:10270712 KIF1B 0.44 6.42 0.33 4.49e-10 Hepatocellular carcinoma; LIHC cis rs17125944 0.615 rs12587286 chr14:53304751 C/T cg00686598 chr14:53173677 PSMC6 0.94 10.61 0.5 6.2e-23 Alzheimer's disease (late onset); LIHC cis rs12477438 0.520 rs13035311 chr2:99717322 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.87 15.32 0.64 1.01e-40 Chronic sinus infection; LIHC cis rs5769765 0.773 rs9616391 chr22:50314573 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.83 -10.04 -0.48 5.99e-21 Schizophrenia; LIHC cis rs651907 0.514 rs11706494 chr3:101509475 A/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs9902453 0.765 rs3102555 chr17:28044101 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 13.49 0.59 1.54e-33 Coffee consumption (cups per day); LIHC cis rs7312933 0.501 rs7296357 chr12:42729891 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.54 -7.98 -0.4 2.17e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg08280861 chr8:58055591 NA 0.53 6.19 0.32 1.72e-9 Developmental language disorder (linguistic errors); LIHC cis rs801193 0.569 rs2659908 chr7:66160822 G/A cg18876405 chr7:65276391 NA 0.33 5.97 0.31 6.1e-9 Aortic root size; LIHC cis rs9948 0.786 rs62152774 chr2:97448377 A/G cg01990225 chr2:97406019 LMAN2L -0.73 -6.31 -0.32 8.85e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs763121 0.925 rs1043312 chr22:39131727 T/G cg06022373 chr22:39101656 GTPBP1 0.61 11.7 0.53 7.98e-27 Menopause (age at onset); LIHC cis rs9902453 0.934 rs8079028 chr17:28484234 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 9.92 0.47 1.48e-20 Coffee consumption (cups per day); LIHC cis rs600231 0.665 rs12790095 chr11:65326086 T/G cg13974409 chr11:65292307 SCYL1 0.38 5.94 0.31 7.14e-9 Bone mineral density; LIHC cis rs2304069 0.955 rs4288106 chr5:149394872 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.95 12.35 0.56 3.25e-29 HIV-1 control; LIHC cis rs637571 0.510 rs12575663 chr11:65574535 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.46 -6.61 -0.34 1.5e-10 Eosinophil percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04571327 chr6:97345972 NDUFAF4 0.44 6.29 0.32 9.8e-10 Lung function (FEV1/FVC); LIHC cis rs12887734 0.524 rs722637 chr14:104261723 G/T cg24130564 chr14:104152367 KLC1 0.42 6.95 0.35 1.87e-11 Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs2153535 0.580 rs9392223 chr6:8468650 G/A cg23788917 chr6:8435910 SLC35B3 0.61 8.68 0.42 1.64e-16 Motion sickness; LIHC cis rs950169 0.650 rs12902052 chr15:85125838 A/T cg17507749 chr15:85114479 UBE2QP1 0.76 8.55 0.42 4.18e-16 Schizophrenia; LIHC cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.07 0.31 3.47e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1707322 1.000 rs4660903 chr1:46457601 A/G cg03146154 chr1:46216737 IPP 0.48 7.93 0.39 3.23e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1949733 0.701 rs2631735 chr4:8476118 A/G cg11789530 chr4:8429930 ACOX3 0.67 8.81 0.43 6.52e-17 Response to antineoplastic agents; LIHC cis rs2380220 0.808 rs2716074 chr6:95907662 T/C cg15832292 chr6:96025679 MANEA -0.63 -7.17 -0.36 4.72e-12 Behavioural disinhibition (generation interaction); LIHC cis rs12602486 1.000 rs2285954 chr17:42232938 T/G cg13607699 chr17:42295918 UBTF -0.75 -6.42 -0.33 4.46e-10 Glycated hemoglobin levels; LIHC cis rs2549003 1.000 rs9282763 chr5:131822133 T/C cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs9303280 0.806 rs8069176 chr17:38057197 G/A cg11212589 chr17:38028394 ZPBP2 0.37 7.67 0.38 1.86e-13 Self-reported allergy; LIHC cis rs2540917 0.581 rs12468946 chr2:60670477 C/T cg00543073 chr2:60773386 BCL11A 0.3 5.82 0.3 1.39e-8 Mean corpuscular volume; LIHC cis rs2153535 0.580 rs2327053 chr6:8443127 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.99 0.4 2.02e-14 Motion sickness; LIHC cis rs9902453 0.765 rs2874505 chr17:28037923 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 12.75 0.57 9.99e-31 Coffee consumption (cups per day); LIHC cis rs763121 0.814 rs5757212 chr22:39053757 G/C cg21395723 chr22:39101663 GTPBP1 0.41 7.0 0.35 1.35e-11 Menopause (age at onset); LIHC cis rs477692 0.905 rs576560 chr10:131420697 C/A cg19680672 chr10:131412579 MGMT -0.42 -6.58 -0.34 1.81e-10 Response to temozolomide; LIHC cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg08132940 chr7:1081526 C7orf50 -0.78 -6.52 -0.33 2.48e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4820539 1.000 rs2267003 chr22:23457098 A/G cg21100191 chr22:23484243 RTDR1 0.85 15.18 0.63 3.67e-40 Bone mineral density; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03209809 chr3:126422892 CHCHD6 0.42 6.49 0.33 3.02e-10 Cognitive function; LIHC cis rs801193 1.000 rs7785213 chr7:66138978 A/C cg11764359 chr7:65958608 NA -0.71 -10.72 -0.5 2.6e-23 Aortic root size; LIHC cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg02290350 chr8:58132656 NA 0.48 9.52 0.46 3.28e-19 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg03517284 chr6:25882590 NA -0.64 -9.07 -0.44 9.68e-18 Blood metabolite levels; LIHC cis rs10256972 0.630 rs10282584 chr7:1081442 C/T cg04025307 chr7:1156635 C7orf50 0.44 6.8 0.35 4.68e-11 Longevity;Endometriosis; LIHC cis rs11212260 0.655 rs80318752 chr11:107226574 C/T cg25435332 chr11:107328525 CWF19L2 0.82 8.27 0.41 3.1e-15 IgG glycosylation; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg12379764 chr21:47803548 PCNT 0.57 8.57 0.42 3.65e-16 Testicular germ cell tumor; LIHC trans rs7618501 0.633 rs7628058 chr3:50039474 C/T cg21659725 chr3:3221576 CRBN 0.7 11.44 0.53 6.82e-26 Intelligence (multi-trait analysis); LIHC cis rs10493773 1.000 rs10493774 chr1:86137963 A/G cg17807903 chr1:86174739 ZNHIT6 -0.48 -7.27 -0.37 2.53e-12 Urate levels in overweight individuals; LIHC cis rs651907 0.535 rs17347156 chr3:101504674 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.63 9.85 0.47 2.65e-20 Colorectal cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg21698385 chr2:102425416 MAP4K4 -0.26 -6.11 -0.31 2.67e-9 Calcium levels; LIHC cis rs965469 0.817 rs6037582 chr20:3351696 C/T cg25506879 chr20:3388711 C20orf194 -0.51 -6.27 -0.32 1.06e-9 IFN-related cytopenia; LIHC cis rs17685 0.753 rs10085567 chr7:75734206 A/C cg01364799 chr7:75623366 TMEM120A -0.47 -7.01 -0.35 1.25e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs992157 0.735 rs13430006 chr2:219113089 A/C cg00012203 chr2:219082015 ARPC2 -0.92 -16.19 -0.66 3.49e-44 Colorectal cancer; LIHC cis rs11098699 0.821 rs6835952 chr4:124230974 A/C cg09941581 chr4:124220074 SPATA5 0.33 6.56 0.33 2.03e-10 Mosquito bite size; LIHC cis rs10028773 0.556 rs4473640 chr4:120260437 G/A cg09307838 chr4:120376055 NA 0.62 9.84 0.47 2.87e-20 Educational attainment; LIHC cis rs79390637 1 rs79390637 chr11:47456867 C/A cg20307385 chr11:47447363 PSMC3 0.59 8.12 0.4 8.73e-15 Intraocular pressure; LIHC cis rs10791323 0.602 rs7946895 chr11:133733893 T/C cg15485101 chr11:133734466 NA 0.27 6.3 0.32 9.31e-10 Childhood ear infection; LIHC cis rs6424115 0.830 rs3123554 chr1:24196401 C/T cg04160030 chr1:24195659 FUCA1 0.38 6.05 0.31 3.8e-9 Immature fraction of reticulocytes; LIHC cis rs950776 0.518 rs12916483 chr15:78832397 G/A cg22563815 chr15:78856949 CHRNA5 0.36 6.65 0.34 1.16e-10 Sudden cardiac arrest; LIHC cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg22800045 chr5:56110881 MAP3K1 0.67 8.56 0.42 3.97e-16 Type 2 diabetes; LIHC cis rs7592578 0.771 rs1128723 chr2:191366707 A/G cg10560079 chr2:191398806 TMEM194B -0.87 -13.02 -0.58 9.04e-32 Diastolic blood pressure; LIHC cis rs11690935 0.959 rs10206062 chr2:172577276 A/T cg13550731 chr2:172543902 DYNC1I2 -0.93 -17.86 -0.69 7.5400000000000006e-51 Schizophrenia; LIHC trans rs9914544 0.545 rs8071458 chr17:18790840 C/A cg21372672 chr17:16614065 CCDC144A -0.27 -6.57 -0.33 1.82e-10 Educational attainment (years of education); LIHC cis rs7312933 0.510 rs61942483 chr12:42499538 T/A cg01256987 chr12:42539512 GXYLT1 -0.67 -12.81 -0.57 5.79e-31 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs12313068 0.600 rs7136207 chr12:110491487 T/C cg12870014 chr12:110450643 ANKRD13A 0.83 11.08 0.51 1.41e-24 Intelligence (multi-trait analysis); LIHC cis rs881375 0.967 rs7864019 chr9:123692868 A/T cg14580859 chr9:123691850 NA 0.4 7.0 0.35 1.39e-11 Rheumatoid arthritis; LIHC trans rs57221529 0.766 rs72706606 chr5:558609 T/C cg25482853 chr8:67687455 SGK3 0.67 6.67 0.34 1.03e-10 Lung disease severity in cystic fibrosis; LIHC cis rs8017423 0.967 rs59006192 chr14:90706456 C/T cg14092571 chr14:90743983 NA -0.37 -5.88 -0.3 9.65e-9 Mortality in heart failure; LIHC cis rs6840360 0.571 rs11940881 chr4:152501050 C/G cg22705602 chr4:152727874 NA -0.34 -6.37 -0.33 5.94e-10 Intelligence (multi-trait analysis); LIHC cis rs7312933 0.558 rs7305397 chr12:42850058 T/C cg01256987 chr12:42539512 GXYLT1 -0.35 -5.85 -0.3 1.18e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs916888 0.773 rs199448 chr17:44809001 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.74 7.09 0.36 7.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs1494950 1.000 rs28706742 chr4:14981651 T/C cg12377275 chr4:15005593 CPEB2 -0.79 -6.71 -0.34 8.25e-11 Political ideology; LIHC cis rs9902453 0.967 rs61014003 chr17:28485233 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.88 0.43 3.97e-17 Coffee consumption (cups per day); LIHC cis rs7216064 1.000 rs7209675 chr17:65831258 A/T cg12091567 chr17:66097778 LOC651250 -0.67 -9.84 -0.47 2.75e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04185861 chr1:154377809 IL6R -0.37 -6.04 -0.31 3.95e-9 Pancreatic cancer; LIHC cis rs7044106 0.762 rs10760107 chr9:123383630 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.82 0.39 6.6e-14 Hip circumference adjusted for BMI; LIHC cis rs677665 0.918 rs11590326 chr1:9339205 A/G cg25755851 chr1:9335794 NA -0.44 -6.78 -0.34 5.36e-11 Eosinophil percentage of white cells; LIHC cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg06481639 chr22:41940642 POLR3H 0.71 7.06 0.36 9.26e-12 Vitiligo; LIHC cis rs807029 0.577 rs701834 chr10:102761801 C/T cg27255678 chr10:102756921 LZTS2 0.53 7.23 0.36 3.2e-12 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9633740 0.504 rs1993484 chr10:82222698 T/C cg01528321 chr10:82214614 TSPAN14 1.1 15.33 0.64 9.76e-41 Post bronchodilator FEV1; LIHC cis rs688020 1.000 rs688020 chr7:4228553 C/T cg24441899 chr7:4244372 SDK1 0.31 6.14 0.32 2.25e-9 Liver fibrosis in pediatric non-alcoholic fatty acid liver disease; LIHC cis rs727563 0.638 rs4820443 chr22:42193913 A/G cg03806693 chr22:41940476 POLR3H -0.95 -10.24 -0.48 1.22e-21 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9393692 0.905 rs6916289 chr6:26289122 A/T cg00631329 chr6:26305371 NA -0.46 -7.66 -0.38 1.9e-13 Educational attainment; LIHC cis rs3796352 1.000 rs11717619 chr3:53003179 A/C cg07884673 chr3:53033167 SFMBT1 0.82 6.27 0.32 1.11e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs6450176 1.000 rs67430852 chr5:53290586 T/A ch.5.1024479R chr5:53302184 ARL15 -0.83 -14.97 -0.63 2.64e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2832191 0.755 rs2832193 chr21:30493589 T/C cg24692254 chr21:30365293 RNF160 -0.59 -10.29 -0.49 8.5e-22 Dental caries; LIHC cis rs782590 0.620 rs7596377 chr2:55888612 T/A cg18811423 chr2:55921094 PNPT1 -0.58 -8.84 -0.43 5.32e-17 Metabolic syndrome; LIHC trans rs6934970 1.000 rs12202385 chr6:113038889 G/C cg09308777 chr6:169852575 NA 0.6 6.21 0.32 1.5e-9 Bipolar disorder (body mass index interaction); LIHC cis rs288342 0.797 rs288312 chr2:183649266 T/C cg02625481 chr2:183667124 NA -0.29 -6.09 -0.31 2.98e-9 Recurrent major depressive disorder; LIHC cis rs9790314 0.502 rs2404342 chr3:161092562 C/T cg03342759 chr3:160939853 NMD3 -0.57 -8.39 -0.41 1.29e-15 Morning vs. evening chronotype; LIHC cis rs17685 0.712 rs7778735 chr7:75770237 T/C cg04610667 chr7:75704037 NA -0.34 -6.12 -0.31 2.58e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs796364 0.806 rs76568708 chr2:200929531 C/T cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.39 -0.37 1.15e-12 Schizophrenia; LIHC cis rs9715521 0.677 rs4490528 chr4:59854572 T/G cg11281224 chr4:60001000 NA -0.33 -6.34 -0.32 7.21e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1707322 1.000 rs34446427 chr1:46417655 A/C cg03146154 chr1:46216737 IPP 0.48 7.84 0.39 5.74e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs7607369 0.580 rs17573731 chr2:219652153 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -5.87 -0.3 1.05e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs79149102 0.579 rs3910748 chr15:75318652 A/G cg17294928 chr15:75287854 SCAMP5 -0.48 -6.2 -0.32 1.61e-9 Lung cancer; LIHC cis rs939574 1.000 rs11552796 chr2:220108300 T/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.99 10.51 0.49 1.38e-22 Platelet distribution width; LIHC cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 8.95 0.44 2.24e-17 Bipolar disorder; LIHC cis rs10540 1.000 rs116876680 chr11:517473 G/T cg03576123 chr11:487126 PTDSS2 -1.03 -7.25 -0.36 2.89e-12 Body mass index; LIHC cis rs58688157 0.705 rs12419618 chr11:611531 G/A cg16486109 chr11:613632 IRF7 0.59 6.21 0.32 1.53e-9 Systemic lupus erythematosus; LIHC trans rs11165623 0.602 rs6677110 chr1:97018734 A/C cg10631902 chr5:14652156 NA -0.25 -6.42 -0.33 4.54e-10 Hip circumference;Waist circumference; LIHC cis rs7122539 0.734 rs4930391 chr11:66645254 A/G cg24851651 chr11:66362959 CCS -0.34 -5.85 -0.3 1.13e-8 HIV-1 susceptibility; LIHC cis rs208520 0.837 rs208509 chr6:66941706 A/G cg07460842 chr6:66804631 NA -0.76 -8.28 -0.41 2.81e-15 Exhaled nitric oxide output; LIHC cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg12016809 chr21:47604291 C21orf56 0.48 7.35 0.37 1.46e-12 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg00656387 chr3:40428638 ENTPD3 0.47 7.79 0.39 7.8500000000000006e-14 Renal cell carcinoma; LIHC cis rs9858542 0.953 rs4625 chr3:49572140 A/G cg03060546 chr3:49711283 APEH -0.48 -6.5 -0.33 2.82e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs11098499 0.955 rs1397608 chr4:120161744 A/G cg25214090 chr10:38739885 LOC399744 0.52 7.95 0.39 2.75e-14 Corneal astigmatism; LIHC cis rs7264396 0.508 rs6060739 chr20:34567592 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.47 -8.22 -0.41 4.23e-15 Total cholesterol levels; LIHC trans rs7618501 0.633 rs4688757 chr3:50035323 T/C cg21659725 chr3:3221576 CRBN 0.71 11.62 0.53 1.58e-26 Intelligence (multi-trait analysis); LIHC cis rs6988636 1.000 rs9987357 chr8:124187620 T/G cg15893493 chr8:124194847 FAM83A 0.89 8.31 0.41 2.26e-15 Urinary uromodulin levels; LIHC cis rs4819052 0.851 rs1006779 chr21:46670752 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.51 7.41 0.37 1.02e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg22105103 chr4:187893119 NA 0.29 7.23 0.36 3.22e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.792 rs4721184 chr7:1950784 T/C cg14004847 chr7:1930337 MAD1L1 -0.5 -7.0 -0.35 1.37e-11 Bipolar disorder and schizophrenia; LIHC cis rs6502050 0.835 rs8080625 chr17:80115447 G/A cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.68e-9 Life satisfaction; LIHC cis rs4969178 0.965 rs12944051 chr17:76395856 C/T cg20026190 chr17:76395443 PGS1 -0.45 -7.19 -0.36 4.1e-12 HDL cholesterol levels; LIHC cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg15691649 chr6:25882328 NA 0.75 10.28 0.49 8.76e-22 Blood metabolite levels; LIHC cis rs1707322 0.964 rs785516 chr1:46564758 T/G cg06784218 chr1:46089804 CCDC17 -0.4 -7.22 -0.36 3.29e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs244293 0.965 rs2170943 chr17:53209505 G/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.39 -0.37 1.1e-12 Menarche (age at onset); LIHC cis rs57590327 0.679 rs35628094 chr3:81605371 C/A cg07356753 chr3:81810745 GBE1 -0.47 -6.48 -0.33 3.21e-10 Extraversion; LIHC cis rs7618501 1.000 rs11130218 chr3:49752372 C/T cg24110177 chr3:50126178 RBM5 0.43 6.65 0.34 1.14e-10 Intelligence (multi-trait analysis); LIHC cis rs6783573 0.535 rs12637699 chr3:46628443 C/T cg16875182 chr3:46619291 LRRC2;TDGF1 -0.52 -5.86 -0.3 1.11e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs7264396 0.635 rs6060703 chr20:34529906 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -10.44 -0.49 2.4e-22 Total cholesterol levels; LIHC cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg15691649 chr6:25882328 NA -0.55 -7.9 -0.39 3.88e-14 Blood metabolite levels; LIHC cis rs11758351 1.000 rs1341759 chr6:26195502 G/A cg03854865 chr6:26224070 HIST1H3E 0.63 7.07 0.36 8.82e-12 Gout;Renal underexcretion gout; LIHC cis rs10411936 1.000 rs1870071 chr19:16505106 A/G cg10248733 chr19:16607483 C19orf44;CALR3 -0.41 -5.75 -0.3 1.98e-8 White blood cell count;Multiple sclerosis; LIHC cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg24693881 chr1:107596107 NA -0.54 -9.46 -0.46 4.95e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs875971 0.545 rs12670811 chr7:65823019 C/A cg11764359 chr7:65958608 NA 0.59 8.23 0.41 4.07e-15 Aortic root size; LIHC cis rs6582630 0.519 rs4002438 chr12:38484880 C/T cg26384229 chr12:38710491 ALG10B 0.69 9.62 0.46 1.47e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs3812831 0.695 rs3118895 chr13:114931742 G/A cg08824895 chr13:115047677 UPF3A 0.49 7.1 0.36 7.08e-12 Schizophrenia; LIHC cis rs12477438 0.520 rs13798 chr2:99813614 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.18 20.84 0.75 7.56e-63 Chronic sinus infection; LIHC cis rs1670533 1.000 rs2045066 chr4:1052401 C/T cg27284194 chr4:1044797 NA 0.59 8.85 0.43 4.64e-17 Recombination rate (females); LIHC cis rs10416265 0.527 rs11084699 chr19:33538393 A/T cg17764715 chr19:33622953 WDR88 0.55 7.53 0.38 4.65e-13 Bone properties (heel); LIHC cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg07424592 chr7:64974309 NA -0.82 -9.43 -0.45 6.33e-19 Diabetic kidney disease; LIHC cis rs12477438 0.605 rs4585080 chr2:99557327 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.75 -10.69 -0.5 3.32e-23 Chronic sinus infection; LIHC cis rs7703051 0.585 rs918623 chr5:74596682 A/C cg06933384 chr5:74808293 COL4A3BP;POLK 0.36 5.93 0.31 7.25e-9 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; LIHC cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg10295955 chr4:187884368 NA 0.97 22.12 0.77 5.9e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.65 0.34 1.19e-10 Bipolar disorder; LIHC trans rs208520 0.754 rs851593 chr6:66875783 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.79 8.87 0.43 4.19e-17 Exhaled nitric oxide output; LIHC cis rs17685 0.753 rs4728586 chr7:75802869 T/C cg01364799 chr7:75623366 TMEM120A -0.52 -7.73 -0.39 1.19e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs546131 0.642 rs61881103 chr11:34838264 C/T cg11058730 chr11:34937778 PDHX;APIP -0.54 -6.69 -0.34 8.9e-11 Lung disease severity in cystic fibrosis; LIHC cis rs10857712 1.000 rs10857712 chr10:135225666 T/C cg15472797 chr10:135243109 NA -0.39 -5.85 -0.3 1.15e-8 Systemic lupus erythematosus; LIHC cis rs9378688 0.654 rs9328087 chr6:2265344 A/G cg12303981 chr6:2244766 GMDS 0.44 5.98 0.31 5.52e-9 Caudate nucleus volume; LIHC cis rs2439831 0.850 rs28504496 chr15:44016883 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.69 0.34 8.9e-11 Lung cancer in ever smokers; LIHC cis rs11030122 0.702 rs7102215 chr11:3943970 C/T cg18678763 chr11:4115507 RRM1 -0.58 -8.59 -0.42 3.21e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs11112613 0.713 rs17037317 chr12:105952058 T/C cg03607813 chr12:105948248 NA 0.63 12.47 0.56 1.14e-29 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs2953174 0.507 rs2953172 chr2:241525316 C/T cg07929629 chr2:241523174 NA 0.58 7.56 0.38 3.62e-13 Bipolar disorder; LIHC cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg05564831 chr3:52568323 NT5DC2 0.36 5.98 0.31 5.54e-9 Bipolar disorder; LIHC cis rs611744 0.967 rs613644 chr8:109188994 G/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg06453172 chr10:134556979 INPP5A -0.62 -7.75 -0.39 1.07e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7917772 0.619 rs2251772 chr10:104470918 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.61 7.28 0.37 2.27e-12 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs10751667 0.666 rs7394992 chr11:980690 G/C ch.11.42038R chr11:967971 AP2A2 0.57 10.21 0.48 1.57e-21 Alzheimer's disease (late onset); LIHC cis rs6120849 0.754 rs6120828 chr20:33674460 A/G cg24642439 chr20:33292090 TP53INP2 0.65 7.0 0.35 1.35e-11 Protein C levels; LIHC cis rs7412746 0.658 rs8444 chr1:150938571 G/A cg17724175 chr1:150552817 MCL1 0.42 8.09 0.4 1.06e-14 Melanoma; LIHC cis rs72781680 1.000 rs72788286 chr2:24098321 A/C cg08917208 chr2:24149416 ATAD2B 0.89 8.29 0.41 2.71e-15 Lymphocyte counts; LIHC cis rs7223966 0.961 rs35844156 chr17:61837568 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 7.08 0.36 8.49e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs651907 0.557 rs62284198 chr3:101474699 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.49 -6.96 -0.35 1.76e-11 Colorectal cancer; LIHC cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.45 0.33 3.92e-10 Bipolar disorder; LIHC cis rs11971779 0.527 rs4379397 chr7:139043385 G/A cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs875971 0.830 rs6967708 chr7:65657313 A/T cg18252515 chr7:66147081 NA 0.42 5.77 0.3 1.79e-8 Aortic root size; LIHC cis rs1983891 0.954 rs1886816 chr6:41544494 A/G cg20194872 chr6:41519635 FOXP4 0.4 6.33 0.32 7.78e-10 Prostate cancer; LIHC cis rs2836950 0.501 rs11702505 chr21:40700614 G/T cg11890956 chr21:40555474 PSMG1 -0.45 -7.32 -0.37 1.78e-12 Menarche (age at onset); LIHC cis rs1494950 1.000 rs79121288 chr4:15012870 A/G cg12377275 chr4:15005593 CPEB2 -0.84 -7.53 -0.38 4.59e-13 Political ideology; LIHC cis rs2153535 0.580 rs9328486 chr6:8528008 T/C cg07606381 chr6:8435919 SLC35B3 0.79 11.5 0.53 4.42e-26 Motion sickness; LIHC cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg02353165 chr6:42928485 GNMT 0.96 15.06 0.63 1.16e-39 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs798766 0.909 rs28521716 chr4:1745751 A/G cg21231739 chr4:1642635 FAM53A -0.38 -6.02 -0.31 4.59e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs9911578 0.935 rs7218105 chr17:57041119 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.79 -0.43 7.66e-17 Intelligence (multi-trait analysis); LIHC cis rs2228479 0.717 rs1800358 chr16:89809319 T/C cg00800038 chr16:89945340 TCF25 -0.61 -9.42 -0.45 7.08e-19 Skin colour saturation; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg18350792 chr12:112563442 TRAFD1 -0.42 -6.25 -0.32 1.19e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs11764590 0.694 rs7801349 chr7:2085553 T/C cg23043544 chr7:2124092 MAD1L1 -0.42 -6.98 -0.35 1.5e-11 Neuroticism; LIHC cis rs3106136 0.843 rs11097414 chr4:95260301 A/T cg11021082 chr4:95130006 SMARCAD1 0.41 7.2 0.36 3.78e-12 Capecitabine sensitivity; LIHC cis rs7107174 1.000 rs7113042 chr11:78035832 C/T cg02023728 chr11:77925099 USP35 -0.45 -8.79 -0.43 7.57e-17 Testicular germ cell tumor; LIHC cis rs9790314 0.645 rs6778254 chr3:160892792 T/C cg03342759 chr3:160939853 NMD3 -0.77 -11.01 -0.51 2.5e-24 Morning vs. evening chronotype; LIHC cis rs7903847 0.673 rs61861870 chr10:99154339 G/T cg06359132 chr10:99160096 RRP12 -0.41 -6.07 -0.31 3.44e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs921968 0.643 rs522377 chr2:219437476 T/C cg18887096 chr2:219472410 PLCD4 0.36 6.29 0.32 9.97e-10 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.935 rs7479914 chr11:49661351 T/C cg15704280 chr7:45808275 SEPT13 -1.01 -21.71 -0.76 2.59e-66 Height; LIHC cis rs7923837 0.687 rs10882101 chr10:94462427 T/C cg25506282 chr10:94462361 NA 0.39 6.92 0.35 2.18e-11 Body mass index;Multiple sclerosis; LIHC cis rs782590 0.935 rs2627779 chr2:55892356 A/G cg03859395 chr2:55845619 SMEK2 0.82 14.14 0.61 4.43e-36 Metabolic syndrome; LIHC cis rs4332037 0.707 rs73046323 chr7:1882795 G/A cg23422044 chr7:1970798 MAD1L1 -0.54 -6.45 -0.33 3.86e-10 Bipolar disorder; LIHC cis rs6545883 0.929 rs55806663 chr2:61740487 G/T cg15711740 chr2:61764176 XPO1 -0.43 -6.07 -0.31 3.32e-9 Tuberculosis; LIHC cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg12311346 chr5:56204834 C5orf35 -0.57 -7.43 -0.37 8.76e-13 Initial pursuit acceleration; LIHC cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg10755058 chr3:40428713 ENTPD3 -0.42 -7.35 -0.37 1.49e-12 Renal cell carcinoma; LIHC cis rs700651 0.624 rs12105927 chr2:198937258 G/A cg00792783 chr2:198669748 PLCL1 0.41 5.92 0.31 7.71e-9 Intracranial aneurysm; LIHC cis rs6964587 0.626 rs34404183 chr7:91551249 T/C cg17063962 chr7:91808500 NA -0.61 -11.02 -0.51 2.23e-24 Breast cancer; LIHC cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.03 -10.57 -0.5 8.95e-23 Platelet count; LIHC cis rs7078219 0.524 rs1548963 chr10:101289703 C/G cg06854084 chr10:101292507 NKX2-3 -0.32 -5.91 -0.3 8.12e-9 Dental caries; LIHC cis rs2153535 0.580 rs7763190 chr6:8484197 G/A cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs7216064 0.765 rs6504550 chr17:65894542 A/G cg12091567 chr17:66097778 LOC651250 -0.64 -9.61 -0.46 1.62e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs6502050 0.764 rs35416122 chr17:80119006 A/G cg11859384 chr17:80120422 CCDC57 -0.43 -5.88 -0.3 9.55e-9 Life satisfaction; LIHC cis rs9905704 0.647 rs33922512 chr17:57114148 C/G cg05425664 chr17:57184151 TRIM37 0.42 6.04 0.31 4.13e-9 Testicular germ cell tumor; LIHC cis rs12594515 1.000 rs7172161 chr15:45990780 A/G cg06207120 chr15:45996521 NA 0.34 6.59 0.34 1.65e-10 Waist circumference;Weight; LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.55 7.87 0.39 4.74e-14 Lymphocyte counts; LIHC cis rs2997447 0.761 rs61776575 chr1:26429844 G/A cg19633962 chr1:26362018 EXTL1 -0.66 -5.86 -0.3 1.11e-8 QRS complex (12-leadsum); LIHC cis rs7116495 1.000 rs679926 chr11:71769936 A/G cg26138937 chr11:71823887 C11orf51 0.79 7.83 0.39 6.05e-14 Severe influenza A (H1N1) infection; LIHC cis rs6121246 0.908 rs6089094 chr20:30431771 C/T cg13852791 chr20:30311386 BCL2L1 0.84 8.92 0.43 2.9e-17 Mean corpuscular hemoglobin; LIHC cis rs11628318 0.508 rs3950014 chr14:103069889 G/A cg23461800 chr14:103021989 NA -0.43 -6.05 -0.31 3.77e-9 Platelet count; LIHC cis rs796364 0.806 rs115717210 chr2:201006247 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg08677398 chr8:58056175 NA 0.41 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7107174 0.892 rs2512519 chr11:77953015 C/T cg02023728 chr11:77925099 USP35 0.49 9.37 0.45 1.01e-18 Testicular germ cell tumor; LIHC cis rs34779708 0.931 rs4934723 chr10:35381763 A/G cg04310649 chr10:35416472 CREM -0.43 -5.79 -0.3 1.57e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1790761 0.692 rs1269981 chr11:67334959 G/A cg01069141 chr11:67398826 TBX10;NUDT8 0.37 6.51 0.33 2.65e-10 Mean corpuscular volume; LIHC trans rs2211698 1.000 rs57158552 chr21:35839201 A/G cg18044562 chr7:50468399 IKZF1 0.51 7.37 0.37 1.28e-12 Cancer; LIHC cis rs9399135 1.000 rs4895435 chr6:135293463 C/A cg24558204 chr6:135376177 HBS1L 0.39 6.46 0.33 3.51e-10 Red blood cell count; LIHC cis rs7903847 0.642 rs1048442 chr10:99160152 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.67 -0.34 1e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs11626933 1.000 rs7146724 chr14:90766092 C/T cg14092571 chr14:90743983 NA -0.9 -14.69 -0.62 3.21e-38 Gut microbiota (bacterial taxa); LIHC trans rs1814175 0.585 rs4881661 chr11:50000117 A/G cg03929089 chr4:120376271 NA -0.82 -15.73 -0.65 2.51e-42 Height; LIHC cis rs11098499 0.863 rs9997631 chr4:120469995 C/G cg09307838 chr4:120376055 NA 0.75 11.52 0.53 3.49e-26 Corneal astigmatism; LIHC cis rs7075426 0.669 rs4934220 chr10:88288206 A/G cg07322936 chr10:88137208 NA -0.45 -5.92 -0.31 7.63e-9 Migraine without aura; LIHC trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg07870213 chr5:140052090 DND1 0.91 9.46 0.46 5.24e-19 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg01768480 chr1:1412855 ATAD3B 0.45 6.25 0.32 1.23e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1144333 1.000 rs1890967 chr1:76459544 T/C cg03433033 chr1:76189801 ACADM 0.54 8.0 0.4 1.92e-14 Attention function in attention deficit hyperactive disorder; LIHC trans rs911555 0.755 rs12435516 chr14:103954404 T/C cg17675199 chr6:35436792 RPL10A -0.44 -9.11 -0.44 7.26e-18 Intelligence (multi-trait analysis); LIHC cis rs2637266 0.783 rs846585 chr10:78494466 T/G cg18941641 chr10:78392320 NA 0.27 5.86 0.3 1.1e-8 Pulmonary function; LIHC cis rs10097731 0.901 rs10464892 chr8:82042991 A/G cg25230327 chr8:82042993 NA 0.54 7.75 0.39 1.03e-13 Serum total protein level; LIHC cis rs1670533 1.000 rs7669399 chr4:1058478 T/G cg27284194 chr4:1044797 NA 0.6 8.97 0.44 1.95e-17 Recombination rate (females); LIHC cis rs7224685 0.569 rs7215798 chr17:4007666 C/G cg11204139 chr17:3907470 NA -0.55 -6.87 -0.35 3.06e-11 Type 2 diabetes; LIHC cis rs7605378 0.752 rs769960 chr2:200710706 G/T cg12253985 chr2:200820533 C2orf60;C2orf47 -0.47 -5.98 -0.31 5.68e-9 Osteoporosis; LIHC cis rs67478160 0.619 rs12885018 chr14:104273812 A/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.57 0.56 4.76e-30 Schizophrenia; LIHC cis rs7223966 1.000 rs11079508 chr17:61750066 T/C cg05941027 chr17:61774174 LIMD2 0.36 7.2 0.36 3.78e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg18279126 chr7:2041391 MAD1L1 0.36 5.83 0.3 1.28e-8 Bipolar disorder and schizophrenia; LIHC cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg05564831 chr3:52568323 NT5DC2 0.35 5.87 0.3 1e-8 Bipolar disorder; LIHC cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.56 0.8 1.79e-77 Prudent dietary pattern; LIHC cis rs2070488 0.965 rs2051215 chr3:38560345 A/G cg24069376 chr3:38537580 EXOG -0.38 -7.0 -0.35 1.34e-11 Electrocardiographic conduction measures; LIHC cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg13770153 chr20:60521292 NA -0.35 -6.95 -0.35 1.84e-11 Body mass index; LIHC cis rs2836950 0.501 rs4818019 chr21:40694456 T/A cg06238570 chr21:40685208 BRWD1 -0.49 -8.0 -0.4 1.94e-14 Menarche (age at onset); LIHC cis rs7927592 0.626 rs11228279 chr11:68309680 C/T cg01657329 chr11:68192670 LRP5 0.5 7.37 0.37 1.26e-12 Total body bone mineral density; LIHC cis rs919433 0.519 rs700658 chr2:198655007 A/T cg03934865 chr2:198174659 NA 0.43 6.28 0.32 1e-9 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7412746 0.658 rs59024312 chr1:150909005 T/G cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs4906332 1.000 rs35344594 chr14:103955792 A/G cg19000871 chr14:103996768 TRMT61A -0.46 -7.86 -0.39 5.04e-14 Coronary artery disease; LIHC cis rs904251 0.523 rs2776874 chr6:37483197 C/T cg01843034 chr6:37503916 NA -0.44 -7.41 -0.37 1.02e-12 Cognitive performance; LIHC cis rs9467773 1.000 rs6924838 chr6:26571756 C/T cg09904177 chr6:26538194 HMGN4 0.66 13.67 0.59 3.1e-34 Intelligence (multi-trait analysis); LIHC cis rs1577917 0.665 rs4304137 chr6:86217448 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 12.01 0.54 5.85e-28 Response to antipsychotic treatment; LIHC cis rs10933610 1.000 rs10933610 chr2:241443654 C/T cg21879648 chr2:241404072 GPC1 0.47 6.16 0.32 1.99e-9 Pursuit maintenance gain; LIHC cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.45 -0.46 5.56e-19 Bipolar disorder and schizophrenia; LIHC cis rs17685 0.753 rs6951943 chr7:75772452 A/G cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.29e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs1801251 0.711 rs778368 chr2:233745333 G/C cg25237894 chr2:233734115 C2orf82 -0.57 -10.71 -0.5 2.75e-23 Coronary artery disease; LIHC cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg13152130 chr6:118910203 C6orf204 -0.62 -6.59 -0.34 1.63e-10 Diastolic blood pressure; LIHC cis rs2386661 0.826 rs12260316 chr10:5659835 C/T cg17085576 chr10:5658249 NA -0.36 -6.46 -0.33 3.67e-10 Breast cancer; LIHC cis rs7258465 1.000 rs271623 chr19:18628947 A/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.28 -0.37 2.34e-12 Breast cancer; LIHC cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs34779708 0.931 rs4351760 chr10:35280254 A/G cg03585969 chr10:35415529 CREM 0.87 13.04 0.58 7.69e-32 Inflammatory bowel disease;Crohn's disease; LIHC trans rs6598955 0.671 rs17163749 chr1:26568165 A/G cg07461501 chr17:79650226 HGS;ARL16 -0.81 -9.1 -0.44 7.57e-18 Obesity-related traits; LIHC trans rs650950 0.528 rs646660 chr11:35528452 C/T cg26832524 chr1:29508259 SFRS4 -0.4 -6.4 -0.33 5.16e-10 Bronchopulmonary dysplasia; LIHC cis rs7582180 0.630 rs13021801 chr2:100935129 C/A cg14675211 chr2:100938903 LONRF2 0.56 8.8 0.43 6.83e-17 Intelligence (multi-trait analysis); LIHC cis rs9790314 0.669 rs7630768 chr3:160864879 T/A cg03342759 chr3:160939853 NMD3 -0.75 -11.45 -0.53 6.55e-26 Morning vs. evening chronotype; LIHC cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs897984 0.683 rs72799316 chr16:30827205 A/G cg02466173 chr16:30829666 NA -0.44 -7.55 -0.38 4.02e-13 Dementia with Lewy bodies; LIHC cis rs74181299 0.964 rs1009358 chr2:65276452 C/T cg05010058 chr2:65284262 CEP68 -0.38 -6.49 -0.33 2.98e-10 Pulse pressure; LIHC cis rs9733 0.519 rs2184833 chr1:150675483 C/T cg18016565 chr1:150552671 MCL1 0.59 11.43 0.53 7.69e-26 Tonsillectomy; LIHC cis rs1215050 0.740 rs2555390 chr4:98999112 A/G cg05340658 chr4:99064831 C4orf37 -0.39 -5.99 -0.31 5.23e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7927592 0.956 rs55816191 chr11:68262979 G/T cg20283391 chr11:68216788 NA -0.52 -7.93 -0.39 3.09e-14 Total body bone mineral density; LIHC cis rs9399135 0.967 rs1854865 chr6:135360300 C/G cg22676075 chr6:135203613 NA 0.4 6.48 0.33 3.19e-10 Red blood cell count; LIHC cis rs2832191 0.716 rs7509628 chr21:30454252 C/T cg24692254 chr21:30365293 RNF160 0.87 15.77 0.65 1.77e-42 Dental caries; LIHC cis rs780096 0.587 rs10205219 chr2:27568565 T/C cg21248554 chr2:27665150 KRTCAP3 -0.42 -5.76 -0.3 1.9e-8 Total body bone mineral density; LIHC cis rs3736594 0.513 rs62131881 chr2:27764781 G/T cg27432699 chr2:27873401 GPN1 0.46 6.79 0.34 4.91e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs10985070 0.507 rs12551347 chr9:123936594 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 5.99 0.31 5.44e-9 Rheumatoid arthritis; LIHC cis rs6960043 0.818 rs2191349 chr7:15064309 G/T cg19272540 chr7:15055459 NA -0.24 -6.53 -0.33 2.41e-10 Type 2 diabetes; LIHC cis rs916888 0.821 rs199504 chr17:44861003 C/T cg15921436 chr17:44337874 NA -0.66 -6.77 -0.34 5.64e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs3780486 0.522 rs10217770 chr9:33146393 C/A cg20290983 chr6:43655470 MRPS18A 0.84 15.3 0.64 1.22e-40 IgG glycosylation; LIHC trans rs877282 0.945 rs12767287 chr10:787310 A/G cg22713356 chr15:30763199 NA 1.35 12.61 0.56 3.43e-30 Uric acid levels; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg20994686 chr17:71306668 CDC42EP4 0.44 6.31 0.32 8.74e-10 Migraine with aura; LIHC cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg21724239 chr8:58056113 NA 0.59 7.32 0.37 1.83e-12 Developmental language disorder (linguistic errors); LIHC cis rs4803468 1.000 rs10853751 chr19:41903220 G/A cg09537434 chr19:41945824 ATP5SL -1.0 -20.91 -0.75 3.87e-63 Height; LIHC cis rs2108622 0.958 rs79400241 chr19:15984402 C/G cg13772218 chr19:15982569 NA 0.4 8.2 0.41 5.08e-15 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs1144333 0.655 rs76992868 chr1:76418916 G/A cg22875332 chr1:76189707 ACADM 0.4 6.06 0.31 3.51e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs6748734 0.779 rs6437371 chr2:241797424 G/C cg20140201 chr2:241835670 C2orf54 -0.5 -7.72 -0.39 1.28e-13 Urinary metabolites; LIHC cis rs6952808 0.862 rs4721167 chr7:1933224 C/T cg21782813 chr7:2030301 MAD1L1 0.42 6.88 0.35 2.9100000000000002e-11 Bipolar disorder and schizophrenia; LIHC cis rs12291225 0.546 rs12795545 chr11:14355564 G/A cg19336497 chr11:14380999 RRAS2 -0.67 -14.08 -0.61 7.9e-36 Sense of smell; LIHC trans rs45567533 0.790 rs7372712 chr3:38686192 C/T cg14758556 chr20:62440591 NA 0.4 6.12 0.31 2.58e-9 PR interval; LIHC cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg04013166 chr16:89971882 TCF25 0.64 8.78 0.43 7.74e-17 Skin colour saturation; LIHC cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg20090690 chr10:134436459 INPP5A 0.44 5.8 0.3 1.5e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs9858542 1.000 rs11718165 chr3:49696797 A/G cg21659725 chr3:3221576 CRBN -0.55 -6.25 -0.32 1.24e-9 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC trans rs7613875 0.580 rs6808044 chr3:50136165 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.42 -6.43 -0.33 4.25e-10 Body mass index; LIHC cis rs41271473 0.500 rs10916366 chr1:228894575 T/C cg00850481 chr1:228891306 NA -0.44 -6.75 -0.34 6.16e-11 Chronic lymphocytic leukemia; LIHC cis rs7582180 0.652 rs11123830 chr2:100974747 A/G cg14675211 chr2:100938903 LONRF2 0.53 8.23 0.41 3.89e-15 Intelligence (multi-trait analysis); LIHC trans rs9929218 0.529 rs8059194 chr16:68749663 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.86 19.16 0.72 4.02e-56 Colorectal cancer; LIHC cis rs6684514 1.000 rs12038481 chr1:156284815 T/C cg16558208 chr1:156270281 VHLL 0.55 10.36 0.49 4.85e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs12464559 0.649 rs4605370 chr2:152628288 C/T cg01189475 chr2:152685088 ARL5A -0.65 -7.83 -0.39 6.38e-14 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs172166 0.694 rs203892 chr6:28067196 T/C cg23485639 chr6:28045615 ZNF165 0.39 6.05 0.31 3.78e-9 Cardiac Troponin-T levels; LIHC cis rs2346177 0.844 rs34791442 chr2:46655169 T/C cg02822958 chr2:46747628 ATP6V1E2 0.4 6.03 0.31 4.34e-9 HDL cholesterol; LIHC cis rs12079745 0.793 rs3753298 chr1:169176899 G/A cg09363564 chr1:169337483 NME7;BLZF1 -0.7 -6.53 -0.33 2.4e-10 QT interval; LIHC cis rs61677309 1.000 rs56224295 chr11:118161891 G/A cg06090739 chr11:118230722 UBE4A 0.34 6.18 0.32 1.83e-9 Lung cancer in ever smokers; LIHC cis rs3741151 1.000 rs3741151 chr11:73020846 G/T cg17517138 chr11:73019481 ARHGEF17 0.96 7.04 0.36 1.06e-11 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs5753618 0.561 rs4603880 chr22:31744721 T/C cg22777020 chr22:31556080 RNF185 0.56 6.46 0.33 3.64e-10 Colorectal cancer; LIHC cis rs9486719 1.000 rs13207333 chr6:96882254 T/C cg06623918 chr6:96969491 KIAA0776 -0.73 -7.18 -0.36 4.27e-12 Migraine;Coronary artery disease; LIHC cis rs9916302 0.851 rs7225096 chr17:37664443 T/C cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg23978390 chr7:1156363 C7orf50 0.6 9.13 0.44 5.9e-18 Longevity;Endometriosis; LIHC cis rs2236918 0.687 rs1776176 chr1:242012554 C/T cg17736920 chr1:242011382 EXO1 0.42 6.16 0.32 2.03e-9 Menopause (age at onset); LIHC cis rs1577917 0.958 rs12196377 chr6:86566775 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -11.18 -0.52 6.29e-25 Response to antipsychotic treatment; LIHC cis rs7223966 1.000 rs8075422 chr17:61804686 G/A cg05941027 chr17:61774174 LIMD2 0.31 6.37 0.33 6.16e-10 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7474896 0.559 rs1735641 chr10:38184852 C/A cg25427524 chr10:38739819 LOC399744 0.46 5.92 0.3 7.9e-9 Obesity (extreme); LIHC cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs34779708 0.897 rs11010131 chr10:35513316 A/C cg04310649 chr10:35416472 CREM -0.43 -5.71 -0.3 2.41e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1506636 0.886 rs6945841 chr7:123266094 G/A cg03229431 chr7:123269106 ASB15 -0.59 -12.3 -0.55 5.06e-29 Plateletcrit;Platelet count; LIHC cis rs2839186 0.656 rs8128380 chr21:47665693 C/T cg00612595 chr21:47717864 NA -0.38 -6.15 -0.32 2.12e-9 Testicular germ cell tumor; LIHC cis rs1552244 0.554 rs28667821 chr3:10050767 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -8.0 -0.4 1.93e-14 Alzheimer's disease; LIHC trans rs3780486 0.846 rs10116966 chr9:33122370 T/A cg04842962 chr6:43655489 MRPS18A 1.05 24.37 0.8 9.63e-77 IgG glycosylation; LIHC cis rs1789 0.903 rs4470622 chr4:15674175 T/G cg21123203 chr4:15471301 CC2D2A -0.43 -6.74 -0.34 6.84e-11 Blood protein levels; LIHC cis rs7772486 0.558 rs702322 chr6:146007166 G/A cg13319975 chr6:146136371 FBXO30 0.55 8.74 0.43 1.1e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs1797081 0.811 rs1797076 chr10:16853076 A/G cg23933602 chr10:16859644 RSU1 0.97 19.49 0.73 1.99e-57 Platelet distribution width; LIHC cis rs2153535 0.580 rs915350 chr6:8443486 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs1775715 0.870 rs11008696 chr10:32218614 G/A cg14930904 chr10:32216787 ARHGAP12 0.38 6.82 0.35 4.25e-11 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs2115630 0.967 rs8027779 chr15:85255385 T/C cg12501888 chr15:85177176 SCAND2 -0.52 -8.06 -0.4 1.28e-14 P wave terminal force; LIHC cis rs4853012 0.838 rs12619982 chr2:74356022 G/A cg05890377 chr2:74357713 NA 0.64 13.1 0.58 4.74e-32 Gestational age at birth (maternal effect); LIHC cis rs4629710 0.568 rs9492883 chr6:131573872 A/T cg12606694 chr6:131520996 AKAP7 0.63 7.31 0.37 1.95e-12 Multiple myeloma (IgH translocation); LIHC cis rs4478858 0.735 rs4494186 chr1:31857847 G/A cg00250761 chr1:31883323 NA 0.3 7.27 0.37 2.43e-12 Alcohol dependence; LIHC cis rs2361718 0.521 rs2361724 chr17:78099114 G/A cg09238746 chr17:78121135 EIF4A3 -0.74 -11.8 -0.54 3.31e-27 Yeast infection; LIHC cis rs67311347 1.000 rs6599102 chr3:40468406 G/A cg09455208 chr3:40491958 NA 0.33 6.65 0.34 1.17e-10 Renal cell carcinoma; LIHC cis rs4919694 1.000 rs75691516 chr10:104652045 C/T cg04362960 chr10:104952993 NT5C2 0.78 7.89 0.39 4.2e-14 Arsenic metabolism; LIHC cis rs918629 0.530 rs17085249 chr5:95236415 C/T cg10483112 chr5:95245456 ELL2 -0.38 -6.89 -0.35 2.69e-11 IgG glycosylation; LIHC cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg02931644 chr1:25747376 RHCE 0.35 7.67 0.38 1.76e-13 Erythrocyte sedimentation rate; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg01535726 chr8:9911482 MSRA -0.42 -6.54 -0.33 2.29e-10 Monocyte count; LIHC cis rs7617480 0.648 rs9859473 chr3:48837182 A/G cg20833759 chr3:49053208 WDR6;DALRD3 0.53 6.38 0.33 5.74e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs9783347 1.000 rs4150550 chr11:18350898 C/G cg15585147 chr11:18324498 HPS5 0.38 6.17 0.32 1.91e-9 Pancreatic cancer; LIHC cis rs2920503 0.959 rs2920502 chr3:12329195 G/C cg23514324 chr3:12329213 PPARG 0.55 7.1 0.36 7.37e-12 LDL cholesterol; LIHC trans rs1814175 0.781 rs12286395 chr11:49954062 C/G cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 1.01e-11 Height; LIHC cis rs12477438 0.765 rs7340412 chr2:99661148 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs9611565 0.644 rs2413652 chr22:42097238 C/T cg03806693 chr22:41940476 POLR3H 0.8 9.07 0.44 9.78e-18 Vitiligo; LIHC cis rs7520050 0.966 rs6677007 chr1:46400590 A/G cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.76 0.3 1.86e-8 Red blood cell count;Reticulocyte count; LIHC cis rs6893300 0.524 rs10516146 chr5:179166974 A/G cg14593053 chr5:179126677 CANX 0.45 8.11 0.4 8.94e-15 Resting heart rate; LIHC cis rs13108904 0.901 rs6851528 chr4:1296009 G/A cg13395646 chr4:1353034 KIAA1530 -0.44 -6.95 -0.35 1.86e-11 Obesity-related traits; LIHC cis rs8141529 0.732 rs11556025 chr22:29168755 T/C cg15103426 chr22:29168792 CCDC117 0.67 11.3 0.52 2.35e-25 Lymphocyte counts; LIHC cis rs614226 0.935 rs7137953 chr12:120894685 C/T cg01236616 chr12:121019343 POP5 -1.19 -18.14 -0.7 5.15e-52 Type 1 diabetes nephropathy; LIHC cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg18252515 chr7:66147081 NA 1.3 16.95 0.68 3.41e-47 Diabetic kidney disease; LIHC cis rs12701220 0.655 rs7778968 chr7:1144622 C/G cg04498913 chr7:1135747 C7orf50 0.42 6.62 0.34 1.37e-10 Bronchopulmonary dysplasia; LIHC cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs9625935 0.518 rs9614086 chr22:30259608 A/C cg01021169 chr22:30184971 ASCC2 0.37 6.32 0.32 8.2e-10 Tonsillectomy; LIHC cis rs8038465 0.615 rs11637315 chr15:73944068 G/C cg15420318 chr15:73925796 NPTN 0.47 7.24 0.36 3.07e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg05368731 chr17:41323189 NBR1 0.71 12.31 0.55 4.27e-29 Menopause (age at onset); LIHC cis rs2839186 0.721 rs13051200 chr21:47701693 A/T cg12016809 chr21:47604291 C21orf56 0.41 5.97 0.31 6.06e-9 Testicular germ cell tumor; LIHC cis rs8005677 0.962 rs11157931 chr14:23403193 A/C cg25600027 chr14:23388339 RBM23 -0.41 -5.9 -0.3 8.79e-9 Cognitive ability (multi-trait analysis); LIHC cis rs2637266 1.000 rs1907317 chr10:78337849 C/A cg18941641 chr10:78392320 NA 0.29 6.14 0.31 2.35e-9 Pulmonary function; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg11235426 chr6:292522 DUSP22 -0.52 -6.87 -0.35 3.11e-11 Menopause (age at onset); LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.36 -5.87 -0.3 1.04e-8 Prudent dietary pattern; LIHC cis rs311392 0.967 rs4255114 chr8:55089450 G/A cg20636351 chr8:55087400 NA -0.39 -7.89 -0.39 4.05e-14 Pelvic organ prolapse (moderate/severe); LIHC cis rs8044995 0.563 rs2279540 chr16:68395061 T/C cg05110241 chr16:68378359 PRMT7 -0.85 -9.58 -0.46 2.07e-19 Schizophrenia; LIHC cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg03517284 chr6:25882590 NA -0.64 -8.97 -0.44 1.95e-17 Blood metabolite levels; LIHC cis rs950169 0.922 rs4842941 chr15:84831312 G/C cg17507749 chr15:85114479 UBE2QP1 -0.73 -8.81 -0.43 6.38e-17 Schizophrenia; LIHC cis rs6933660 0.800 rs9383893 chr6:151757327 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.62 10.12 0.48 3.1e-21 Menarche (age at onset); LIHC cis rs921968 0.540 rs6746040 chr2:219588890 G/T cg02985541 chr2:219472218 PLCD4 -0.38 -6.59 -0.34 1.63e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs6088590 1.000 rs6058111 chr20:33310999 T/C cg24642439 chr20:33292090 TP53INP2 0.81 11.62 0.53 1.54e-26 Coronary artery disease; LIHC cis rs11958404 1.000 rs72816538 chr5:157414303 A/G cg05962755 chr5:157440814 NA 0.86 10.11 0.48 3.51e-21 IgG glycosylation; LIHC cis rs6061231 0.597 rs624313 chr20:60927412 G/A cg24112000 chr20:60950667 NA 0.46 7.34 0.37 1.54e-12 Colorectal cancer; LIHC trans rs7395662 0.571 rs4882020 chr11:48615658 C/T cg03929089 chr4:120376271 NA -0.4 -6.09 -0.31 3.02e-9 HDL cholesterol; LIHC cis rs67478160 0.643 rs7156697 chr14:104211136 G/A cg08213375 chr14:104286397 PPP1R13B 0.65 12.66 0.56 2.18e-30 Schizophrenia; LIHC trans rs12478296 1.000 rs12469535 chr2:243044147 G/A cg01596870 chr19:55963115 NA -0.64 -8.65 -0.42 2.07e-16 Obesity-related traits; LIHC cis rs3859192 0.599 rs12451897 chr17:38179275 G/T cg17344932 chr17:38183730 MED24;SNORD124 0.8 16.51 0.67 1.99e-45 White blood cell count; LIHC cis rs7520050 0.931 rs11211213 chr1:46342517 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11626933 1.000 rs7149083 chr14:90754006 G/A cg04374321 chr14:90722782 PSMC1 0.48 6.55 0.33 2.14e-10 Gut microbiota (bacterial taxa); LIHC cis rs826838 0.935 rs1601579 chr12:39178606 G/C cg13010199 chr12:38710504 ALG10B 0.5 6.04 0.31 4.04e-9 Heart rate; LIHC cis rs5758511 0.680 rs739147 chr22:42671066 T/G cg00645731 chr22:42541494 CYP2D7P1 0.52 8.25 0.41 3.57e-15 Birth weight; LIHC cis rs1198430 0.759 rs946267 chr1:23747703 A/T cg19827787 chr1:23763612 ASAP3 0.27 5.91 0.3 8.36e-9 Total cholesterol levels; LIHC cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg25894440 chr7:65020034 NA -0.55 -6.42 -0.33 4.51e-10 Diabetic kidney disease; LIHC trans rs11098499 0.739 rs10013032 chr4:120149419 C/T cg25214090 chr10:38739885 LOC399744 -0.38 -6.25 -0.32 1.22e-9 Corneal astigmatism; LIHC cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.18 11.45 0.53 6.23e-26 Platelet count; LIHC cis rs11822910 0.911 rs61886978 chr11:57194848 G/C cg00522883 chr11:57194120 SLC43A3 0.66 8.7 0.43 1.43e-16 Platelet distribution width; LIHC cis rs3020736 0.500 rs4147638 chr22:42487900 G/A cg15557168 chr22:42548783 NA 0.44 6.95 0.35 1.81e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs4891159 0.790 rs72975930 chr18:74144645 G/A cg24786174 chr18:74118243 ZNF516 -0.74 -13.35 -0.59 5e-33 Longevity; LIHC cis rs875971 0.862 rs11763189 chr7:65983529 G/A cg18252515 chr7:66147081 NA -0.44 -6.3 -0.32 8.93e-10 Aortic root size; LIHC cis rs11785400 1.000 rs11776301 chr8:143737142 A/G cg24634471 chr8:143751801 JRK 0.51 8.25 0.41 3.41e-15 Schizophrenia; LIHC cis rs9816226 0.591 rs75160594 chr3:185810481 C/G cg00760338 chr3:185826511 ETV5 -0.71 -5.99 -0.31 5.27e-9 Obesity;Body mass index; LIHC cis rs2668423 0.922 rs3826942 chr19:1360575 A/G cg02639931 chr19:1387894 NDUFS7 0.63 9.41 0.45 7.54e-19 Nonalcoholic fatty liver disease; LIHC cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg11070056 chr1:107600091 PRMT6 0.7 12.12 0.55 2.31e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs3796352 1.000 rs33999310 chr3:52883332 G/A cg04865290 chr3:52927548 TMEM110 -0.49 -6.19 -0.32 1.74e-9 Immune reponse to smallpox (secreted IL-2); LIHC trans rs1814175 0.645 rs1721997 chr11:49916653 T/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.02 -0.73 1.41e-59 Height; LIHC cis rs1559088 1.000 rs28840147 chr19:33561976 A/G cg17764715 chr19:33622953 WDR88 0.42 5.77 0.3 1.74e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs1799949 0.931 rs34474989 chr17:41445410 A/T cg23758822 chr17:41437982 NA 0.94 17.57 0.69 1.04e-49 Menopause (age at onset); LIHC cis rs713477 0.967 rs11158039 chr14:55906696 A/T cg13175173 chr14:55914753 NA -0.35 -8.13 -0.4 8e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg00280220 chr17:61926910 NA 0.42 6.73 0.34 7.18e-11 Prudent dietary pattern; LIHC cis rs1538970 0.924 rs12037201 chr1:45941349 G/T cg05343316 chr1:45956843 TESK2 0.59 8.72 0.43 1.23e-16 Platelet count; LIHC cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg10360323 chr17:41437877 NA 0.4 6.03 0.31 4.17e-9 Menopause (age at onset); LIHC cis rs6066825 0.644 rs6090894 chr20:47334688 G/T cg18078177 chr20:47281410 PREX1 0.41 6.67 0.34 1.05e-10 Colorectal cancer; LIHC cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -13.82 -0.6 8.38e-35 Alzheimer's disease; LIHC cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg03188948 chr7:1209495 NA 0.46 6.46 0.33 3.5e-10 Longevity;Endometriosis; LIHC cis rs2439831 1.000 rs2439831 chr15:43784475 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 8.97 0.44 1.97e-17 Lung cancer in ever smokers; LIHC cis rs11583043 0.958 rs12746722 chr1:101464789 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.69 8.96 0.44 2.09e-17 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs611744 0.905 rs640950 chr8:109157819 T/A cg21045802 chr8:109455806 TTC35 0.46 7.69 0.38 1.62e-13 Dupuytren's disease; LIHC cis rs1348850 0.567 rs3770012 chr2:178538023 A/G cg02961200 chr2:178257176 LOC100130691;AGPS -0.61 -8.21 -0.41 4.62e-15 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7914558 1.000 rs10748838 chr10:104943986 T/A cg15744005 chr10:104629667 AS3MT -0.38 -8.55 -0.42 4.22e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg17554472 chr22:41940697 POLR3H 0.51 5.81 0.3 1.45e-8 Vitiligo; LIHC cis rs7312933 0.703 rs10492388 chr12:42608001 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 7.69 0.38 1.54e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg06238570 chr21:40685208 BRWD1 -0.47 -7.64 -0.38 2.14e-13 Cognitive function; LIHC cis rs8180040 0.767 rs11920853 chr3:47308183 G/A cg27129171 chr3:47204927 SETD2 -0.56 -9.02 -0.44 1.41e-17 Colorectal cancer; LIHC cis rs12477438 0.798 rs2309524 chr2:99659510 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.1 -15.68 -0.65 3.82e-42 Chronic sinus infection; LIHC cis rs2153535 0.580 rs6929206 chr6:8447961 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.74 0.43 1.04e-16 Motion sickness; LIHC cis rs7937682 0.921 rs34584980 chr11:111441537 G/A cg09085632 chr11:111637200 PPP2R1B 0.9 10.12 0.48 3.12e-21 Primary sclerosing cholangitis; LIHC cis rs79057730 0.599 rs112891948 chr7:816059 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.79 9.08 0.44 8.77e-18 Initial pursuit acceleration; LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg02592271 chr2:27665507 KRTCAP3 -0.44 -5.95 -0.31 6.49e-9 Total body bone mineral density; LIHC cis rs6840360 0.615 rs12641433 chr4:152607548 A/C cg22705602 chr4:152727874 NA -0.34 -7.19 -0.36 4.18e-12 Intelligence (multi-trait analysis); LIHC trans rs2727020 0.521 rs7946190 chr11:49521964 T/A cg03929089 chr4:120376271 NA 0.7 10.21 0.48 1.57e-21 Coronary artery disease; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg16132339 chr22:24313637 DDTL;DDT 0.81 16.74 0.67 2.26e-46 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs12310956 0.532 rs11494810 chr12:33952881 C/A cg26384229 chr12:38710491 ALG10B 0.5 6.91 0.35 2.43e-11 Morning vs. evening chronotype; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg13409248 chr3:40428643 ENTPD3 -0.5 -8.45 -0.42 8.34e-16 Renal cell carcinoma; LIHC cis rs7772486 0.655 rs2142981 chr6:146071695 G/C cg05347473 chr6:146136440 FBXO30 -0.37 -5.99 -0.31 5.38e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs10870270 0.784 rs10430614 chr10:133748640 C/T cg26149184 chr10:133730230 NA -0.41 -6.52 -0.33 2.51e-10 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs7582720 1.000 rs7582720 chr2:203753072 T/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs652260 1.000 rs652260 chr19:7900562 C/T cg26014689 chr19:7917955 EVI5L -0.67 -11.64 -0.53 1.34e-26 Menarche (age at onset); LIHC cis rs151997 1.000 rs62367382 chr5:50246715 T/C cg06027927 chr5:50259733 NA 0.62 7.86 0.39 5.18e-14 Callous-unemotional behaviour; LIHC cis rs860295 0.719 rs490608 chr1:155682870 C/T cg02153340 chr1:155202674 NA -0.31 -5.77 -0.3 1.77e-8 Body mass index; LIHC cis rs9910055 0.550 rs113844752 chr17:42297631 C/A cg10896456 chr17:42255109 ASB16;C17orf65 0.36 6.55 0.33 2.06e-10 Total body bone mineral density; LIHC cis rs17253792 0.822 rs7145064 chr14:56088860 C/T cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg05590025 chr7:65112418 INTS4L2 0.58 6.43 0.33 4.21e-10 Diabetic kidney disease; LIHC cis rs6456156 0.586 rs1358883 chr6:167467433 C/G cg07741184 chr6:167504864 NA -0.27 -6.58 -0.34 1.76e-10 Primary biliary cholangitis; LIHC cis rs1538970 0.884 rs61788261 chr1:45899114 G/A cg24296786 chr1:45957014 TESK2 -0.5 -7.17 -0.36 4.59e-12 Platelet count; LIHC cis rs6665290 0.904 rs9727512 chr1:227185375 G/T cg10327440 chr1:227177885 CDC42BPA -1.18 -25.81 -0.81 2.79e-82 Myeloid white cell count; LIHC cis rs17401966 0.838 rs7553935 chr1:10375179 G/A cg15208524 chr1:10270712 KIF1B 0.38 5.81 0.3 1.42e-8 Hepatocellular carcinoma; LIHC cis rs1400745 0.729 rs1741196 chr14:35347020 G/A cg05294307 chr14:35346193 BAZ1A -0.46 -7.73 -0.39 1.2e-13 Monocyte count; LIHC cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg16405210 chr4:1374714 KIAA1530 0.59 9.42 0.45 6.8e-19 Obesity-related traits; LIHC cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg22561889 chr6:118971681 C6orf204 0.55 5.94 0.31 7.13e-9 Diastolic blood pressure; LIHC cis rs35110281 0.641 rs9983670 chr21:45083425 A/G cg04455712 chr21:45112962 RRP1B 0.51 8.58 0.42 3.44e-16 Mean corpuscular volume; LIHC cis rs1949733 0.701 rs1880024 chr4:8454639 A/G cg11789530 chr4:8429930 ACOX3 0.76 11.0 0.51 2.74e-24 Response to antineoplastic agents; LIHC cis rs10078 0.515 rs1053299 chr5:470760 G/A cg26072250 chr5:443457 EXOC3;C5orf55 0.75 10.04 0.48 5.94e-21 Fat distribution (HIV); LIHC trans rs867371 1.000 rs9944197 chr15:82450602 G/A cg18393722 chr15:85113863 UBE2QP1 -0.4 -6.89 -0.35 2.7e-11 Cognitive ability;Cognitive ability (multi-trait analysis); LIHC trans rs6058796 1.000 rs6087972 chr20:31268102 A/G cg02600331 chr11:130417168 NA 0.36 7.59 0.38 2.98e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs244293 0.730 rs9898020 chr17:53057715 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.48 -7.24 -0.36 2.9e-12 Menarche (age at onset); LIHC cis rs9911578 0.785 rs10853008 chr17:56993407 T/C cg05425664 chr17:57184151 TRIM37 0.55 7.73 0.39 1.19e-13 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.43 0.45 6.55e-19 Bipolar disorder; LIHC cis rs4803468 0.967 rs67047091 chr19:41938684 C/T cg09537434 chr19:41945824 ATP5SL 1.02 21.19 0.75 2.98e-64 Height; LIHC cis rs919433 0.684 rs55775495 chr2:198245965 C/T cg10820045 chr2:198174542 NA 0.56 9.19 0.44 3.93e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs75908454 1.000 rs77366054 chr6:169857167 C/T cg19338460 chr6:170058176 WDR27 -0.83 -7.89 -0.39 4.22e-14 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs8180040 0.966 rs878659 chr3:47500662 G/A cg16586182 chr3:47516702 SCAP -0.58 -11.26 -0.52 3.19e-25 Colorectal cancer; LIHC cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg19536664 chr17:6899085 ALOX12 0.35 6.08 0.31 3.18e-9 Tonsillectomy; LIHC cis rs3096299 0.933 rs2965823 chr16:89454924 G/A cg08822215 chr16:89438651 ANKRD11 -0.43 -6.88 -0.35 2.84e-11 Multiple myeloma (IgH translocation); LIHC cis rs9394841 0.667 rs9357366 chr6:41786976 T/G cg08135965 chr6:41755394 TOMM6 0.46 6.15 0.32 2.17e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs6542838 0.554 rs4311103 chr2:99538362 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.45 -7.41 -0.37 9.96e-13 Fear of minor pain; LIHC cis rs9814567 1.000 rs11708531 chr3:134224902 T/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.95 -0.31 6.7e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg06873352 chr17:61820015 STRADA 0.61 9.43 0.45 6.58e-19 Height; LIHC cis rs780096 0.546 rs1260320 chr2:27722416 A/G cg21248554 chr2:27665150 KRTCAP3 0.44 6.01 0.31 4.84e-9 Total body bone mineral density; LIHC cis rs986417 1.000 rs4901985 chr14:60948318 A/C cg27398547 chr14:60952738 C14orf39 0.77 8.96 0.44 2.13e-17 Gut microbiota (bacterial taxa); LIHC cis rs7772486 0.790 rs2254288 chr6:146204470 G/A cg13319975 chr6:146136371 FBXO30 -0.34 -5.71 -0.3 2.43e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg16049864 chr8:95962084 TP53INP1 -0.6 -11.49 -0.53 4.52e-26 Type 2 diabetes; LIHC cis rs1494950 1.000 rs57517602 chr4:14977442 C/T cg12377275 chr4:15005593 CPEB2 -0.79 -6.71 -0.34 8.25e-11 Political ideology; LIHC cis rs12594515 1.000 rs11855562 chr15:45995659 C/T cg06207120 chr15:45996521 NA 0.31 5.84 0.3 1.25e-8 Waist circumference;Weight; LIHC cis rs11626933 1.000 rs11626016 chr14:90747979 C/T cg07150772 chr14:90864620 CALM1 -0.42 -5.87 -0.3 1.03e-8 Gut microbiota (bacterial taxa); LIHC cis rs919433 0.713 rs6719483 chr2:198472886 A/G cg10820045 chr2:198174542 NA 0.51 8.08 0.4 1.12e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs11626933 1.000 rs11621007 chr14:90743967 G/A cg07150772 chr14:90864620 CALM1 -0.41 -5.84 -0.3 1.23e-8 Gut microbiota (bacterial taxa); LIHC cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg08219700 chr8:58056026 NA 0.5 6.34 0.32 7.14e-10 Developmental language disorder (linguistic errors); LIHC cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg11764359 chr7:65958608 NA 0.59 6.01 0.31 4.63e-9 Diabetic kidney disease; LIHC cis rs7769051 1.000 rs9493446 chr6:133125643 C/T cg22852734 chr6:133119734 C6orf192 0.92 9.44 0.45 5.9e-19 Type 2 diabetes nephropathy; LIHC cis rs748404 0.697 rs554001 chr15:43551919 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.47 8.21 0.41 4.51e-15 Lung cancer; LIHC cis rs35146811 0.961 rs1880949 chr7:99722266 A/C cg22906224 chr7:99728672 NA -0.43 -6.08 -0.31 3.17e-9 Coronary artery disease; LIHC trans rs208520 0.690 rs12194057 chr6:66745616 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.93 0.43 2.63e-17 Exhaled nitric oxide output; LIHC cis rs5769765 0.913 rs4824111 chr22:50284305 A/G cg02269571 chr22:50332266 NA 0.72 9.54 0.46 2.7e-19 Schizophrenia; LIHC cis rs11822910 0.815 rs12422015 chr11:57193653 A/G cg00522883 chr11:57194120 SLC43A3 0.67 8.57 0.42 3.67e-16 Platelet distribution width; LIHC cis rs11048434 0.761 rs1805721 chr12:9147569 A/G cg04155231 chr12:9217510 LOC144571 -0.31 -5.9 -0.3 8.53e-9 Sjögren's syndrome; LIHC trans rs208520 0.690 rs12197578 chr6:66725905 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 8.91 0.43 3.16e-17 Exhaled nitric oxide output; LIHC cis rs2070488 0.965 rs35091896 chr3:38443320 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.04 0.66 1.46e-43 Electrocardiographic conduction measures; LIHC cis rs74181299 0.533 rs6705891 chr2:65368095 T/A cg05010058 chr2:65284262 CEP68 -0.36 -5.74 -0.3 2.04e-8 Pulse pressure; LIHC cis rs6570726 0.935 rs391820 chr6:145821284 C/T cg23711669 chr6:146136114 FBXO30 0.54 9.75 0.47 5.8e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg00149659 chr3:10157352 C3orf10 0.63 6.87 0.35 2.99e-11 Alzheimer's disease; LIHC cis rs6748734 0.817 rs4465762 chr2:241798862 G/A cg04034577 chr2:241836375 C2orf54 -0.44 -10.09 -0.48 3.87e-21 Urinary metabolites; LIHC cis rs8062405 1.000 rs8062405 chr16:28837906 C/T cg16576597 chr16:28551801 NUPR1 -0.39 -6.52 -0.33 2.6e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7582180 0.564 rs2309795 chr2:100954290 G/A cg14675211 chr2:100938903 LONRF2 0.54 8.67 0.42 1.76e-16 Intelligence (multi-trait analysis); LIHC cis rs12477438 1.000 rs995617 chr2:99857904 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.73 7.5 0.38 5.65e-13 Chronic sinus infection; LIHC cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg19723775 chr5:179050963 HNRNPH1 0.39 6.11 0.31 2.78e-9 Lung cancer; LIHC cis rs2991971 0.934 rs11580609 chr1:45975856 C/G cg24296786 chr1:45957014 TESK2 0.54 8.04 0.4 1.5e-14 High light scatter reticulocyte count; LIHC cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.09 -0.31 3.09e-9 Total body bone mineral density; LIHC cis rs2404602 0.647 rs1443115 chr15:77041829 T/C cg03037974 chr15:76606532 NA -0.6 -9.99 -0.48 8.46e-21 Blood metabolite levels; LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC trans rs9323205 0.531 rs55928212 chr14:51543439 G/A cg02322135 chr4:113969312 ANK2 0.44 6.33 0.32 7.77e-10 Cancer; LIHC cis rs7617773 0.539 rs12486935 chr3:48390164 C/T cg11946769 chr3:48343235 NME6 0.58 7.06 0.36 9.61e-12 Coronary artery disease; LIHC cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg23978390 chr7:1156363 C7orf50 0.52 7.91 0.39 3.61e-14 Longevity;Endometriosis; LIHC cis rs7223966 1.000 rs9903903 chr17:61762044 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 7.16 0.36 4.92e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs4764487 0.710 rs7964366 chr12:6346478 T/C cg08284733 chr12:6341482 CD9 0.38 6.44 0.33 4.12e-10 Mean platelet volume; LIHC cis rs10751667 0.643 rs7395613 chr11:933873 C/T cg06064525 chr11:970664 AP2A2 -0.55 -14.76 -0.62 1.8e-38 Alzheimer's disease (late onset); LIHC cis rs9901225 1 rs9901225 chr17:40755811 C/T cg14558262 chr17:40713999 COASY 0.7 11.6 0.53 1.79e-26 Colorectal or endometrial cancer; LIHC cis rs950169 0.800 rs4842847 chr15:84931199 G/A cg03959625 chr15:84868606 LOC388152 0.48 6.87 0.35 3.07e-11 Schizophrenia; LIHC cis rs6456156 0.692 rs9457270 chr6:167512928 A/G cg23791538 chr6:167370224 RNASET2 -0.47 -7.36 -0.37 1.39e-12 Primary biliary cholangitis; LIHC cis rs6964587 0.869 rs6975243 chr7:91514672 G/A cg17063962 chr7:91808500 NA -0.98 -18.31 -0.7 1.11e-52 Breast cancer; LIHC cis rs6604026 0.522 rs12756786 chr1:93044955 G/A cg13858687 chr1:93297071 RPL5 0.59 5.71 0.3 2.43e-8 Multiple sclerosis; LIHC cis rs61677309 1.000 rs7110019 chr11:118168617 A/G cg06090739 chr11:118230722 UBE4A 0.34 6.27 0.32 1.06e-9 Lung cancer in ever smokers; LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs10197940 0.624 rs4461258 chr2:152429679 A/G cg19508488 chr2:152266495 RIF1 -0.53 -7.6 -0.38 2.87e-13 Lung cancer; LIHC cis rs10876993 0.784 rs10083154 chr12:58020933 G/A cg15848620 chr12:58087721 OS9 0.49 6.32 0.32 7.95e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg03396347 chr1:1875803 NA -0.46 -8.38 -0.41 1.36e-15 Body mass index; LIHC cis rs1873147 0.569 rs11071710 chr15:63309193 A/G cg21584241 chr15:63341463 TPM1 0.44 6.38 0.33 5.9e-10 Orofacial clefts; LIHC cis rs9457247 0.663 rs9457257 chr6:167440736 G/A cg07741184 chr6:167504864 NA 0.26 6.17 0.32 1.95e-9 Crohn's disease; LIHC cis rs875971 0.867 rs13227219 chr7:65844062 T/A cg18876405 chr7:65276391 NA 0.33 5.76 0.3 1.92e-8 Aortic root size; LIHC cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg06466757 chr4:1255808 NA 0.34 5.72 0.3 2.38e-8 Obesity-related traits; LIHC cis rs10752881 0.740 rs1889307 chr1:183049389 T/A ch.1.3577855R chr1:183094577 LAMC1 0.61 10.69 0.5 3.29e-23 Colorectal cancer; LIHC cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg05025164 chr4:1340916 KIAA1530 0.52 7.88 0.39 4.34e-14 Obesity-related traits; LIHC cis rs66569888 0.789 rs66826026 chr2:106732879 C/T cg23109721 chr2:106886537 NA -0.65 -6.31 -0.32 8.64e-10 Facial morphology (factor 23); LIHC cis rs61990749 0.597 rs13379065 chr14:78141295 C/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.62 -10.3 -0.49 7.3e-22 Fibroblast growth factor basic levels; LIHC cis rs7726839 0.574 rs72705017 chr5:623733 G/A cg09021430 chr5:549028 NA -0.42 -8.48 -0.42 7.01e-16 Obesity-related traits; LIHC trans rs9926296 0.618 rs8058179 chr16:89846987 C/T cg13698153 chr12:118541722 VSIG10 -0.63 -7.12 -0.36 6.55e-12 Vitiligo; LIHC cis rs11673344 0.764 rs513406 chr19:37439147 G/A cg27390819 chr19:37464633 NA -0.52 -6.22 -0.32 1.42e-9 Obesity-related traits; LIHC cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg19318889 chr4:1322082 MAEA 0.43 5.95 0.31 6.65e-9 Obesity-related traits; LIHC trans rs1814175 0.616 rs1722001 chr11:49894427 A/G cg15704280 chr7:45808275 SEPT13 -0.96 -19.99 -0.73 1.9e-59 Height; LIHC cis rs8044995 0.563 rs61602448 chr16:68377520 C/T cg09835421 chr16:68378352 PRMT7 -0.83 -9.75 -0.47 5.66e-20 Schizophrenia; LIHC cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg13409248 chr3:40428643 ENTPD3 -0.46 -8.03 -0.4 1.62e-14 Renal cell carcinoma; LIHC cis rs769267 0.930 rs1054930 chr19:19648346 G/C cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.72 0.3 2.32e-8 Tonsillectomy; LIHC cis rs4906332 1.000 rs17617832 chr14:103943140 T/C cg19000871 chr14:103996768 TRMT61A -0.47 -7.98 -0.4 2.26e-14 Coronary artery disease; LIHC cis rs1707322 1.000 rs6693336 chr1:46354595 C/T cg03146154 chr1:46216737 IPP 0.47 7.68 0.38 1.69e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs3849570 1.000 rs9842330 chr3:81814688 G/A cg07356753 chr3:81810745 GBE1 -0.63 -10.58 -0.5 8.37e-23 Waist circumference;Body mass index; LIHC cis rs11792861 0.591 rs7044275 chr9:111717138 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.68 11.05 0.51 1.78e-24 Menarche (age at onset); LIHC cis rs317689 0.788 rs317679 chr12:69693172 A/C cg19645103 chr12:69753606 YEATS4 -0.47 -6.39 -0.33 5.32e-10 Response to diuretic therapy; LIHC cis rs17685 0.753 rs1637051 chr7:75730659 G/A cg01364799 chr7:75623366 TMEM120A -0.5 -7.41 -0.37 9.97e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg17971929 chr21:40555470 PSMG1 -0.81 -9.56 -0.46 2.42e-19 Cognitive function; LIHC cis rs3770081 1.000 rs6718632 chr2:86176084 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -8.69 -0.43 1.52e-16 Facial emotion recognition (sad faces); LIHC trans rs12478296 0.901 rs7423119 chr2:243005488 T/A cg01596870 chr19:55963115 NA -0.67 -9.79 -0.47 3.98e-20 Obesity-related traits; LIHC cis rs9911578 0.935 rs2567912 chr17:56731270 T/C cg05425664 chr17:57184151 TRIM37 -0.58 -8.66 -0.42 1.91e-16 Intelligence (multi-trait analysis); LIHC cis rs3762637 1.000 rs9842736 chr3:122161101 C/T cg24169773 chr3:122142474 KPNA1 -0.5 -9.71 -0.47 7.4e-20 LDL cholesterol levels; LIHC cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg06634786 chr22:41940651 POLR3H 0.81 8.74 0.43 1.08e-16 Vitiligo; LIHC cis rs4788570 0.647 rs904764 chr16:71772795 G/A cg06353428 chr16:71660113 MARVELD3 1.36 14.23 0.61 2.1e-36 Intelligence (multi-trait analysis); LIHC cis rs2334880 0.680 rs1364210 chr16:71603487 G/A cg06353428 chr16:71660113 MARVELD3 -1.27 -10.94 -0.51 4.4e-24 Malaria; LIHC cis rs7707921 0.505 rs12516434 chr5:81428072 T/A cg15871215 chr5:81402204 ATG10 0.65 7.21 0.36 3.54e-12 Breast cancer; LIHC cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.56 10.52 0.49 1.29e-22 Total body bone mineral density; LIHC cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg03517284 chr6:25882590 NA 0.6 8.49 0.42 6.25e-16 Blood metabolite levels; LIHC cis rs2404602 0.647 rs11632765 chr15:76974261 A/T cg03037974 chr15:76606532 NA 0.59 10.1 0.48 3.62e-21 Blood metabolite levels; LIHC cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg18918831 chr3:195489782 MUC4 0.72 11.15 0.52 8.01e-25 Lung disease severity in cystic fibrosis; LIHC cis rs6461049 0.765 rs10224497 chr7:2149967 A/G cg02951883 chr7:2050386 MAD1L1 -0.65 -10.51 -0.49 1.42e-22 Schizophrenia; LIHC cis rs4665809 0.816 rs2384359 chr2:26371364 T/C cg27170947 chr2:26402098 FAM59B -0.72 -8.84 -0.43 5.12e-17 Gut microbiome composition (summer); LIHC cis rs6570726 0.557 rs403956 chr6:145829956 T/C cg13319975 chr6:146136371 FBXO30 -0.56 -8.87 -0.43 4.04e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs6088590 1.000 rs6087632 chr20:33407704 A/C cg06115741 chr20:33292138 TP53INP2 0.59 8.18 0.4 5.51e-15 Coronary artery disease; LIHC trans rs1814175 0.817 rs1615305 chr11:49895222 T/A cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs4555082 0.834 rs11849607 chr14:105745383 G/A cg10792982 chr14:105748885 BRF1 0.45 5.98 0.31 5.47e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9790314 1.000 rs6765269 chr3:160948542 T/C cg04691961 chr3:161091175 C3orf57 -0.38 -5.94 -0.31 6.96e-9 Morning vs. evening chronotype; LIHC cis rs9902453 0.817 rs4294865 chr17:28205736 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.56 8.62 0.42 2.48e-16 Coffee consumption (cups per day); LIHC cis rs9457247 1.000 rs406095 chr6:167409087 C/T cg12798992 chr6:167411361 FGFR1OP 0.61 10.21 0.48 1.58e-21 Crohn's disease; LIHC trans rs3112255 1.000 rs2942904 chr2:101306999 A/G cg06958034 chr1:23346203 KDM1A -0.46 -6.06 -0.31 3.55e-9 Intelligence (multi-trait analysis); LIHC cis rs9911578 0.730 rs55759249 chr17:57027135 A/G cg05425664 chr17:57184151 TRIM37 0.53 7.28 0.37 2.25e-12 Intelligence (multi-trait analysis); LIHC cis rs3857067 0.806 rs6825522 chr4:95108140 G/T cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.58 -0.38 3.29e-13 QT interval; LIHC cis rs7103648 0.864 rs12801188 chr11:47388214 G/A cg20307385 chr11:47447363 PSMC3 0.87 12.82 0.57 5.54e-31 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs7772486 0.875 rs1929523 chr6:146339989 T/A cg23711669 chr6:146136114 FBXO30 0.67 11.83 0.54 2.59e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg18402987 chr7:1209562 NA 0.88 6.35 0.32 6.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25832598 chr1:247094143 AHCTF1 0.45 6.45 0.33 3.77e-10 Pancreatic cancer; LIHC cis rs17001868 0.568 rs3788578 chr22:40742921 C/T cg07138101 chr22:40742427 ADSL 0.55 6.46 0.33 3.62e-10 Mammographic density (dense area); LIHC cis rs6952808 0.500 rs3778996 chr7:2177190 G/A cg02951883 chr7:2050386 MAD1L1 -0.61 -9.68 -0.46 9.48e-20 Bipolar disorder and schizophrenia; LIHC cis rs7909074 0.651 rs10900127 chr10:45390103 C/A cg04218760 chr10:45406644 TMEM72 -0.21 -6.04 -0.31 3.97e-9 Mean corpuscular volume; LIHC cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.29 -5.83 -0.3 1.26e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs3820068 0.524 rs34094056 chr1:15824154 G/T cg17385448 chr1:15911702 AGMAT 0.36 6.06 0.31 3.53e-9 Systolic blood pressure; LIHC cis rs6762 0.748 rs3059 chr11:840319 C/T cg07691484 chr11:842764 TSPAN4;POLR2L -0.75 -9.53 -0.46 3.07e-19 Mean platelet volume; LIHC cis rs892961 0.932 rs7224442 chr17:75413439 A/G cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs2576037 0.796 rs6507718 chr18:44581284 G/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.48 -7.34 -0.37 1.59e-12 Personality dimensions; LIHC cis rs6089829 0.962 rs6062776 chr20:61663736 A/G cg08564027 chr20:61660810 NA 0.4 7.61 0.38 2.71e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs10751667 0.666 rs10902242 chr11:949700 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.16 0.48 2.3e-21 Alzheimer's disease (late onset); LIHC cis rs1552244 0.688 rs113940455 chr3:10014165 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.67 -10.13 -0.48 2.92e-21 Alzheimer's disease; LIHC cis rs7582180 0.629 rs4850927 chr2:100969067 A/G cg14675211 chr2:100938903 LONRF2 0.56 8.78 0.43 8e-17 Intelligence (multi-trait analysis); LIHC cis rs11673344 0.543 rs8108429 chr19:37636776 A/C cg27390819 chr19:37464633 NA -0.44 -5.87 -0.3 1.04e-8 Obesity-related traits; LIHC trans rs11722228 0.522 rs73212817 chr4:10064011 T/C cg26043149 chr18:55253948 FECH 0.83 10.06 0.48 4.95e-21 Gout;Urate levels;Serum uric acid levels; LIHC cis rs7106204 1.000 rs4244512 chr11:24217355 A/G ch.11.24196551F chr11:24239977 NA -0.7 -7.06 -0.36 9.63e-12 Response to Homoharringtonine (cytotoxicity); LIHC cis rs4917833 0.764 rs1925645 chr10:100220472 T/C cg19043522 chr10:100227446 HPSE2 0.4 5.73 0.3 2.22e-8 Pediatric bone mineral density (femoral neck); LIHC trans rs7615952 0.673 rs35955861 chr3:125626201 T/C cg07211511 chr3:129823064 LOC729375 -0.83 -8.71 -0.43 1.31e-16 Blood pressure (smoking interaction); LIHC cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs11122272 0.668 rs2790874 chr1:231537988 A/G cg06096015 chr1:231504339 EGLN1 0.49 9.07 0.44 9.41e-18 Hemoglobin concentration; LIHC cis rs738322 0.640 rs738321 chr22:38568833 C/G cg25457927 chr22:38595422 NA -0.35 -8.7 -0.43 1.38e-16 Cutaneous nevi; LIHC trans rs11088226 0.801 rs2833886 chr21:33923872 C/A cg09050820 chr6:167586206 TCP10L2 0.75 12.38 0.56 2.5e-29 Gastritis; LIHC cis rs8028182 0.525 rs9920028 chr15:75927717 G/A cg20655648 chr15:75932815 IMP3 0.46 6.61 0.34 1.45e-10 Sudden cardiac arrest; LIHC cis rs1801251 1.000 rs35212961 chr2:233582762 C/T cg08000102 chr2:233561755 GIGYF2 0.77 11.49 0.53 4.48e-26 Coronary artery disease; LIHC cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg02951883 chr7:2050386 MAD1L1 -0.78 -13.63 -0.59 4.53e-34 Bipolar disorder and schizophrenia; LIHC cis rs7116495 1.000 rs7127865 chr11:71747781 G/C cg26138937 chr11:71823887 C11orf51 -0.81 -8.08 -0.4 1.11e-14 Severe influenza A (H1N1) infection; LIHC cis rs55665837 0.961 rs11023226 chr11:14458817 C/T cg19336497 chr11:14380999 RRAS2 -0.44 -7.99 -0.4 2.15e-14 Vitamin D levels; LIHC cis rs7072216 0.763 rs10883092 chr10:100167276 A/C cg26618903 chr10:100175079 PYROXD2 -0.38 -6.09 -0.31 3.03e-9 Metabolite levels; LIHC cis rs7635838 0.859 rs9812885 chr3:11508326 G/C cg00170343 chr3:11313890 ATG7 0.4 6.18 0.32 1.79e-9 HDL cholesterol; LIHC cis rs9291683 0.588 rs12506364 chr4:10023448 C/T cg11266682 chr4:10021025 SLC2A9 0.34 7.34 0.37 1.54e-12 Bone mineral density; LIHC cis rs1003719 0.680 rs8130069 chr21:38552116 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.71 -10.78 -0.5 1.62e-23 Eye color traits; LIHC cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg12463550 chr7:65579703 CRCP 0.71 7.04 0.36 1.05e-11 Diabetic kidney disease; LIHC cis rs76533333 0.564 rs34658917 chr13:113417423 C/T cg08557188 chr13:113420371 ATP11A -0.8 -6.06 -0.31 3.58e-9 Red cell distribution width; LIHC cis rs9916302 0.904 rs4795359 chr17:37573146 C/T cg07936489 chr17:37558343 FBXL20 -0.84 -13.48 -0.59 1.65e-33 Glomerular filtration rate (creatinine); LIHC cis rs6545883 0.929 rs7606167 chr2:61742654 C/G cg14146966 chr2:61757674 XPO1 0.47 8.19 0.41 5.17e-15 Tuberculosis; LIHC cis rs9457247 0.565 rs12178491 chr6:167512474 C/T cg12798992 chr6:167411361 FGFR1OP 0.4 6.1 0.31 2.92e-9 Crohn's disease; LIHC cis rs7399018 1.000 rs7399018 chr12:51610365 C/T cg25754956 chr12:51612065 POU6F1 -0.73 -10.15 -0.48 2.5e-21 Cisplatin-induced ototoxicity; LIHC trans rs3960554 0.529 rs1859795 chr7:75877354 A/G cg19862616 chr7:65841803 NCRNA00174 0.6 9.34 0.45 1.23e-18 Eotaxin levels; LIHC cis rs116095464 0.510 rs55750776 chr5:230467 T/C cg22857025 chr5:266934 NA -1.48 -18.27 -0.7 1.56e-52 Breast cancer; LIHC trans rs526821 0.595 rs504661 chr11:55312683 A/G cg15704280 chr7:45808275 SEPT13 -0.5 -7.63 -0.38 2.31e-13 Pediatric bone mineral density (spine); LIHC cis rs858239 0.568 rs6970694 chr7:23250828 T/C cg18081818 chr7:23246105 NA -0.42 -6.02 -0.31 4.5e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs4713118 0.662 rs9468278 chr6:28028482 C/T cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs921968 0.541 rs4674310 chr2:219318078 T/C cg02985541 chr2:219472218 PLCD4 -0.44 -7.18 -0.36 4.25e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.26 -0.61 1.62e-36 Alzheimer's disease; LIHC cis rs7258015 1.000 rs7258015 chr19:10449358 T/C cg13981319 chr19:10446556 ICAM3 0.47 7.26 0.37 2.59e-12 Systemic lupus erythematosus or rheumatoid arthritis; LIHC trans rs11098499 0.863 rs6835635 chr4:120458867 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.42 0.45 7.14e-19 Corneal astigmatism; LIHC cis rs9457247 1.000 rs2149090 chr6:167372764 T/C cg23791538 chr6:167370224 RNASET2 0.68 11.67 0.53 9.94e-27 Crohn's disease; LIHC cis rs3820068 0.581 rs72645889 chr1:15930251 T/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs1577917 0.710 rs1059306 chr6:86388109 G/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.49 8.51 0.42 5.58e-16 Response to antipsychotic treatment; LIHC cis rs7131987 0.650 rs7973786 chr12:29462744 C/T cg12903224 chr12:29470962 FAR2 -0.41 -6.73 -0.34 7.35e-11 QT interval; LIHC cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg05025164 chr4:1340916 KIAA1530 0.75 11.75 0.54 5.45e-27 Longevity; LIHC cis rs7666738 0.546 rs13141117 chr4:98892798 G/A cg05340658 chr4:99064831 C4orf37 0.5 6.58 0.34 1.8e-10 Colonoscopy-negative controls vs population controls; LIHC trans rs11098499 0.954 rs10006877 chr4:120242793 C/T cg25214090 chr10:38739885 LOC399744 0.6 9.57 0.46 2.28e-19 Corneal astigmatism; LIHC cis rs4819052 0.679 rs4819053 chr21:46711357 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 -0.48 -7.18 -0.36 4.42e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2479724 0.811 rs6905726 chr6:41750812 T/C cg17623882 chr6:41773611 USP49 0.55 8.76 0.43 9.14e-17 Menarche (age at onset); LIHC cis rs9916302 0.665 rs4795369 chr17:37609120 G/A cg07936489 chr17:37558343 FBXL20 -0.77 -12.18 -0.55 1.37e-28 Glomerular filtration rate (creatinine); LIHC cis rs60871478 0.592 rs4275123 chr7:857352 A/G cg00934597 chr7:893267 UNC84A -0.51 -5.94 -0.31 6.84e-9 Cerebrospinal P-tau181p levels; LIHC cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg06558623 chr16:89946397 TCF25 0.98 14.33 0.61 8.56e-37 Skin colour saturation; LIHC cis rs2569991 1.000 rs2569991 chr3:12923197 C/A cg07263372 chr3:12940286 IQSEC1 -0.34 -5.8 -0.3 1.54e-8 Periodontitis (DPAL); LIHC cis rs55665837 0.540 rs11023302 chr11:14693935 C/G cg00085434 chr11:14927489 NA 0.41 5.81 0.3 1.41e-8 Vitamin D levels; LIHC cis rs9916302 0.861 rs33933929 chr17:37426441 A/C cg00129232 chr17:37814104 STARD3 -0.4 -6.45 -0.33 3.88e-10 Glomerular filtration rate (creatinine); LIHC cis rs72781680 0.821 rs113014365 chr2:24159903 C/T cg08917208 chr2:24149416 ATAD2B 0.65 6.57 0.33 1.86e-10 Lymphocyte counts; LIHC cis rs9733 0.519 rs3768005 chr1:150680988 A/T cg15448220 chr1:150897856 SETDB1 0.43 6.77 0.34 5.77e-11 Tonsillectomy; LIHC cis rs597539 0.652 rs667989 chr11:68685776 T/A cg04772025 chr11:68637568 NA 0.48 6.08 0.31 3.18e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg07677032 chr17:61819896 STRADA 0.42 6.13 0.31 2.36e-9 Prudent dietary pattern; LIHC trans rs877282 0.838 rs34778553 chr10:796865 T/C cg22713356 chr15:30763199 NA 1.36 12.63 0.56 2.86e-30 Uric acid levels; LIHC cis rs6545883 0.929 rs9679557 chr2:61709349 C/A cg14146966 chr2:61757674 XPO1 0.48 8.26 0.41 3.21e-15 Tuberculosis; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11829033 chr10:74927882 FAM149B1;ECD 0.41 6.19 0.32 1.71e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs898097 0.585 rs9893200 chr17:80893028 A/C cg15664640 chr17:80829946 TBCD 0.43 7.12 0.36 6.32e-12 Breast cancer; LIHC cis rs6062302 0.522 rs2236503 chr20:62224595 G/A cg06363034 chr20:62225388 GMEB2 -0.45 -7.6 -0.38 2.8e-13 Glioblastoma; LIHC cis rs6466055 0.720 rs10227302 chr7:105021829 C/G cg04380332 chr7:105027541 SRPK2 -0.38 -7.02 -0.35 1.2e-11 Schizophrenia; LIHC cis rs2250402 0.510 rs2898984 chr15:40324075 G/C cg10636054 chr15:40330586 SRP14 0.67 8.29 0.41 2.61e-15 Corneal curvature; LIHC cis rs7615952 1.000 rs7615952 chr3:125649403 A/C cg05084668 chr3:125655381 ALG1L 0.52 7.6 0.38 2.83e-13 Blood pressure (smoking interaction); LIHC cis rs1008375 0.966 rs2286773 chr4:17616214 C/A cg02297831 chr4:17616191 MED28 0.5 7.74 0.39 1.12e-13 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs36051895 0.632 rs10815167 chr9:5150058 A/G cg02405213 chr9:5042618 JAK2 -0.68 -12.25 -0.55 7.47e-29 Pediatric autoimmune diseases; LIHC cis rs559928 0.606 rs55970968 chr11:63961433 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 7.63 0.38 2.3e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7116495 0.748 rs481355 chr11:71578356 G/A cg26138937 chr11:71823887 C11orf51 0.7 6.86 0.35 3.27e-11 Severe influenza A (H1N1) infection; LIHC trans rs7193541 0.564 rs4888274 chr16:74706298 A/T cg23598604 chr1:99732472 LPPR4 -0.3 -6.2 -0.32 1.61e-9 Multiple myeloma; LIHC cis rs2274273 0.934 rs10140869 chr14:55795283 G/A cg01864836 chr14:55583639 NA -0.37 -6.49 -0.33 3.06e-10 Protein biomarker; LIHC cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg19318889 chr4:1322082 MAEA 0.5 7.95 0.39 2.83e-14 Longevity; LIHC cis rs4919087 0.962 rs10882889 chr10:99045890 A/G cg25902810 chr10:99078978 FRAT1 0.7 10.35 0.49 4.92e-22 Monocyte count; LIHC cis rs875971 0.964 rs778708 chr7:65856319 T/C cg18876405 chr7:65276391 NA 0.37 6.73 0.34 7.38e-11 Aortic root size; LIHC cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg21448741 chr8:58168803 NA 0.37 6.61 0.34 1.46e-10 Developmental language disorder (linguistic errors); LIHC cis rs311392 0.554 rs311386 chr8:55101507 A/G cg11783602 chr8:55087084 NA -0.31 -6.23 -0.32 1.37e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs743757 1.000 rs2282754 chr3:50436827 T/C cg12708802 chr3:50388878 TUSC4;CYB561D2 0.48 7.39 0.37 1.13e-12 Diastolic blood pressure; LIHC cis rs2303759 0.881 rs10412811 chr19:49884495 G/A cg22307029 chr19:49891270 CCDC155 0.57 9.26 0.45 2.39e-18 Multiple sclerosis; LIHC cis rs769267 0.931 rs15622 chr19:19468734 G/A cg15052019 chr19:19431593 KIAA0892;SF4 -0.43 -6.12 -0.31 2.6e-9 Tonsillectomy; LIHC cis rs208515 0.592 rs10944862 chr6:66674215 C/T cg07460842 chr6:66804631 NA 0.78 9.04 0.44 1.21e-17 Exhaled nitric oxide levels; LIHC cis rs11931598 0.511 rs35772786 chr4:7021211 T/G cg26116260 chr4:7069785 GRPEL1 0.55 9.35 0.45 1.19e-18 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; LIHC cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.98 -0.31 5.68e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.16 11.6 0.53 1.92e-26 Platelet count; LIHC cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg05665937 chr4:1216051 CTBP1 0.46 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs11711311 1.000 rs34475696 chr3:113458293 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.39 0.45 8.39e-19 IgG glycosylation; LIHC cis rs2404602 0.622 rs11637296 chr15:77207885 C/A cg03037974 chr15:76606532 NA -0.54 -8.9 -0.43 3.4e-17 Blood metabolite levels; LIHC cis rs10911232 0.507 rs4652772 chr1:183023696 C/G ch.1.3577855R chr1:183094577 LAMC1 -0.59 -10.33 -0.49 6.08e-22 Hypertriglyceridemia; LIHC cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg03806693 chr22:41940476 POLR3H -1.11 -13.22 -0.58 1.69e-32 Vitiligo; LIHC cis rs801193 1.000 rs2420824 chr7:66131116 G/A cg11764359 chr7:65958608 NA -0.71 -10.45 -0.49 2.25e-22 Aortic root size; LIHC cis rs61990749 0.597 rs2267761 chr14:78147849 G/C cg21497246 chr14:78225524 SNW1;C14orf178 0.51 7.66 0.38 1.9e-13 Fibroblast growth factor basic levels; LIHC cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg15691649 chr6:25882328 NA -0.45 -5.78 -0.3 1.71e-8 Intelligence (multi-trait analysis); LIHC cis rs28489187 0.683 rs12047422 chr1:85848830 T/G cg16011679 chr1:85725395 C1orf52 0.46 5.78 0.3 1.73e-8 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs6840360 0.571 rs875667 chr4:152525477 G/A cg22705602 chr4:152727874 NA -0.32 -6.23 -0.32 1.38e-9 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs2808601 chr1:231536571 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.64 -10.27 -0.49 9.53e-22 Hemoglobin concentration; LIHC cis rs939574 0.656 rs113370390 chr2:220132837 T/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.93 6.35 0.32 6.75e-10 Platelet distribution width; LIHC cis rs4684776 0.867 rs1470613 chr3:11347525 G/A cg00170343 chr3:11313890 ATG7 -0.52 -7.21 -0.36 3.53e-12 Small vessel stroke; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg06420487 chr17:61919686 SMARCD2 0.42 5.76 0.3 1.88e-8 Height; LIHC cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg18279126 chr7:2041391 MAD1L1 0.37 5.74 0.3 2.12e-8 Bipolar disorder and schizophrenia; LIHC cis rs3015497 1.000 rs4075253 chr14:51107737 G/A cg09863266 chr14:51125203 SAV1 -0.43 -7.02 -0.35 1.2e-11 Mean platelet volume; LIHC cis rs6503525 0.628 rs4065985 chr17:38101932 G/C cg17344932 chr17:38183730 MED24;SNORD124 -0.38 -5.95 -0.31 6.75e-9 Asthma; LIHC cis rs7572733 0.534 rs734037 chr2:198749269 G/A cg00792783 chr2:198669748 PLCL1 0.47 6.85 0.35 3.5e-11 Dermatomyositis; LIHC cis rs2836950 0.501 rs2836983 chr21:40689336 G/A cg11890956 chr21:40555474 PSMG1 -0.42 -6.74 -0.34 6.64e-11 Menarche (age at onset); LIHC cis rs7000551 0.751 rs1116084 chr8:22395309 C/T cg12081754 chr8:22256438 SLC39A14 0.48 7.6 0.38 2.83e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs2839627 0.598 rs2246573 chr21:44253016 C/T cg03543861 chr21:44258195 NA -0.48 -7.5 -0.38 5.39e-13 Information processing speed; LIHC cis rs1801251 1.000 rs283474 chr2:233654627 A/G cg25237894 chr2:233734115 C2orf82 0.58 11.41 0.53 9.22e-26 Coronary artery disease; LIHC cis rs34779708 0.733 rs11597184 chr10:35397396 G/A cg04310649 chr10:35416472 CREM -0.43 -5.86 -0.3 1.1e-8 Inflammatory bowel disease;Crohn's disease; LIHC trans rs11165623 0.792 rs6671371 chr1:96977039 A/G cg10631902 chr5:14652156 NA -0.32 -7.5 -0.38 5.43e-13 Hip circumference;Waist circumference; LIHC cis rs11958404 0.932 rs72816543 chr5:157416464 A/G cg05962755 chr5:157440814 NA 1.05 11.56 0.53 2.49e-26 IgG glycosylation; LIHC cis rs12682352 0.602 rs4841044 chr8:8664940 A/G cg06636001 chr8:8085503 FLJ10661 -0.43 -6.47 -0.33 3.41e-10 Neuroticism; LIHC cis rs7212590 0.618 rs56142307 chr17:57878149 A/G cg10252138 chr17:58120427 NA -0.6 -6.03 -0.31 4.16e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs10540 0.915 rs35333170 chr11:526478 A/G cg03352830 chr11:487213 PTDSS2 0.78 6.36 0.33 6.6e-10 Body mass index; LIHC cis rs4820294 0.926 rs62236671 chr22:38069305 G/A cg00142150 chr22:38071001 LGALS1 0.7 11.22 0.52 4.27e-25 Fat distribution (HIV); LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs600806 0.778 rs2115787 chr1:110003840 T/G cg10127483 chr1:110009974 SYPL2 0.49 6.02 0.31 4.55e-9 Intelligence (multi-trait analysis); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg21276834 chr21:30365048 RNF160 -0.48 -6.82 -0.35 4.19e-11 Pancreatic cancer; LIHC cis rs7086627 0.515 rs7077373 chr10:82211615 C/T cg00277334 chr10:82204260 NA -0.85 -14.26 -0.61 1.54e-36 Post bronchodilator FEV1; LIHC cis rs1728785 1.000 rs11648314 chr16:68596775 A/G cg02972257 chr16:68554789 NA -0.58 -6.9 -0.35 2.5e-11 Ulcerative colitis; LIHC cis rs6089829 0.962 rs7267951 chr20:61665979 A/G cg03213289 chr20:61660250 NA 0.5 8.97 0.44 1.99e-17 Prostate cancer (SNP x SNP interaction); LIHC cis rs116095464 0.558 rs13354585 chr5:242263 G/C cg22496380 chr5:211416 CCDC127 -1.03 -10.64 -0.5 4.88e-23 Breast cancer; LIHC cis rs17401966 0.540 rs1467653 chr1:10413123 A/G cg19773385 chr1:10388646 KIF1B 0.33 5.83 0.3 1.26e-8 Hepatocellular carcinoma; LIHC trans rs7178375 1.000 rs28693590 chr15:31195021 A/G cg04373760 chr16:53404718 NA 0.6 7.77 0.39 9.42e-14 Hypertriglyceridemia; LIHC cis rs11148252 0.904 rs9536079 chr13:53030565 G/A cg00495681 chr13:53174319 NA 0.42 6.96 0.35 1.77e-11 Lewy body disease; LIHC cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg07308232 chr7:1071921 C7orf50 -0.47 -7.82 -0.39 6.67e-14 Longevity;Endometriosis; LIHC cis rs9467711 0.559 rs13208916 chr6:26601940 G/A cg09904177 chr6:26538194 HMGN4 -0.53 -5.72 -0.3 2.37e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs919433 0.680 rs788017 chr2:198265173 T/A cg10820045 chr2:198174542 NA 0.55 8.96 0.44 2.12e-17 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs116095464 0.558 rs10065239 chr5:275288 C/T cg22496380 chr5:211416 CCDC127 -1.1 -10.33 -0.49 5.84e-22 Breast cancer; LIHC cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg24209194 chr3:40518798 ZNF619 0.64 9.65 0.46 1.24e-19 Renal cell carcinoma; LIHC cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg11060661 chr22:24314208 DDT;DDTL 0.54 8.73 0.43 1.18e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs752010 0.530 rs10789401 chr1:42081111 A/G cg06885757 chr1:42089581 HIVEP3 0.5 7.24 0.36 2.95e-12 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs56104184 0.830 rs73061617 chr19:49350984 G/A cg15549821 chr19:49342101 PLEKHA4 -1.17 -9.72 -0.47 7.12e-20 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs4908768 0.906 rs55858268 chr1:8554696 C/T cg25722041 chr1:8623473 RERE 0.41 5.85 0.3 1.18e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg24219929 chr15:60884748 RORA -0.45 -6.34 -0.32 7.28e-10 Alopecia areata; LIHC cis rs6499255 0.951 rs7198242 chr16:69648495 C/T cg15192750 chr16:69999425 NA -0.49 -7.37 -0.37 1.3e-12 IgE levels; LIHC cis rs4631830 0.733 rs4512771 chr10:51540906 C/A cg20129853 chr10:51489980 NA -0.4 -8.78 -0.43 7.77e-17 Prostate-specific antigen levels; LIHC cis rs798554 0.959 rs798528 chr7:2772431 A/C cg13628971 chr7:2884303 GNA12 0.53 7.82 0.39 6.5e-14 Height; LIHC cis rs4819052 0.851 rs4819044 chr21:46660118 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.04e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2370759 1.000 rs75984055 chr10:32591276 T/C cg01819863 chr10:32635814 EPC1 1.11 16.37 0.66 6.78e-45 Sexual dysfunction (female); LIHC cis rs151997 0.962 rs27272 chr5:50181865 A/G cg06027927 chr5:50259733 NA 0.57 7.61 0.38 2.61e-13 Callous-unemotional behaviour; LIHC cis rs2070488 0.965 rs2300668 chr3:38540541 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.92 -16.16 -0.66 4.79e-44 Electrocardiographic conduction measures; LIHC cis rs7727544 0.735 rs272860 chr5:131684175 C/G cg24060327 chr5:131705240 SLC22A5 -0.57 -8.18 -0.4 5.71e-15 Blood metabolite levels; LIHC cis rs875971 0.862 rs10250544 chr7:65766561 A/G cg18876405 chr7:65276391 NA -0.34 -6.23 -0.32 1.38e-9 Aortic root size; LIHC trans rs2243480 1.000 rs34193460 chr7:65393110 A/G cg10756647 chr7:56101905 PSPH 1.11 13.46 0.59 1.9e-33 Diabetic kidney disease; LIHC cis rs7085104 0.514 rs284855 chr10:104574422 A/G cg15744005 chr10:104629667 AS3MT 0.38 8.12 0.4 8.63e-15 Immature fraction of reticulocytes;Schizophrenia; LIHC cis rs6964587 1.000 rs6961928 chr7:91669808 C/T cg17063962 chr7:91808500 NA 1.03 20.7 0.75 2.82e-62 Breast cancer; LIHC cis rs8177179 0.904 rs1130459 chr3:133465283 A/G cg18769074 chr3:133464867 TF 0.27 5.87 0.3 1.06e-8 Iron status biomarkers (transferrin levels); LIHC cis rs12744310 0.943 rs12032906 chr1:41769158 T/C cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1862618 0.853 rs252910 chr5:56192983 G/A cg22800045 chr5:56110881 MAP3K1 0.63 7.71 0.38 1.42e-13 Initial pursuit acceleration; LIHC cis rs2274273 1.000 rs7140872 chr14:55612744 C/T cg01864836 chr14:55583639 NA -0.36 -6.12 -0.31 2.62e-9 Protein biomarker; LIHC cis rs6752107 1.000 rs13009506 chr2:234175706 A/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 -0.54 -8.25 -0.41 3.5e-15 Crohn's disease;Inflammatory bowel disease; LIHC cis rs5758511 0.514 rs3985938 chr22:42511727 G/T cg00645731 chr22:42541494 CYP2D7P1 0.52 8.34 0.41 1.84e-15 Birth weight; LIHC cis rs2274273 0.870 rs6573009 chr14:55682324 A/C cg04306507 chr14:55594613 LGALS3 0.33 6.38 0.33 5.91e-10 Protein biomarker; LIHC trans rs11098499 0.863 rs13149407 chr4:120437825 A/G cg25214090 chr10:38739885 LOC399744 0.63 10.15 0.48 2.56e-21 Corneal astigmatism; LIHC cis rs1577917 0.958 rs10944137 chr6:86454314 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -11.12 -0.52 9.63e-25 Response to antipsychotic treatment; LIHC cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 9.75 0.47 5.42e-20 Mean platelet volume; LIHC cis rs2576037 0.583 rs646128 chr18:44397691 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 9.74 0.47 5.96e-20 Personality dimensions; LIHC cis rs9921222 0.521 rs62032884 chr16:363415 C/T cg26944245 chr16:421049 TMEM8A;MRPL28 0.45 7.49 0.38 5.95e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs45544231 0.593 rs1075367 chr16:52555002 G/A cg09051775 chr16:52580266 TOX3 -0.31 -5.73 -0.3 2.19e-8 Restless legs syndrome; LIHC cis rs2836974 0.666 rs4818015 chr21:40675493 A/C cg17971929 chr21:40555470 PSMG1 0.46 6.69 0.34 9.16e-11 Cognitive function; LIHC cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg02187348 chr16:89574699 SPG7 0.61 9.73 0.47 6.44e-20 Multiple myeloma (IgH translocation); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25666489 chr19:37663856 ZNF585A 0.4 6.13 0.31 2.44e-9 Cognitive function; LIHC trans rs7618501 0.933 rs6809431 chr3:49804119 A/G cg21582582 chr3:182698605 DCUN1D1 0.52 6.87 0.35 3.02e-11 Intelligence (multi-trait analysis); LIHC cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg03806693 chr22:41940476 POLR3H 1.12 13.03 0.58 8.92e-32 Vitiligo; LIHC cis rs7089973 0.624 rs1359080 chr10:116582419 C/A cg23260525 chr10:116636907 FAM160B1 0.36 7.14 0.36 5.67e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs28647808 0.881 rs28625799 chr9:136264557 C/T cg14268506 chr9:136215580 SNORD36B;MED22;SNORD24;RPL7A -0.75 -5.8 -0.3 1.53e-8 Blood protein levels; LIHC cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg09455208 chr3:40491958 NA 0.38 7.62 0.38 2.58e-13 Renal cell carcinoma; LIHC cis rs9549367 0.789 rs9549698 chr13:113877701 A/G cg00898013 chr13:113819073 PROZ -0.42 -7.26 -0.37 2.58e-12 Platelet distribution width; LIHC cis rs2242116 0.727 rs4683298 chr3:46966387 C/G cg16586182 chr3:47516702 SCAP -0.38 -6.57 -0.33 1.83e-10 Birth weight; LIHC cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg13397359 chr6:42928475 GNMT 0.81 11.4 0.52 9.47e-26 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs7572733 0.555 rs35563720 chr2:198923075 A/G cg10820045 chr2:198174542 NA 0.43 6.24 0.32 1.28e-9 Dermatomyositis; LIHC cis rs10508774 0.925 rs12242792 chr10:32831905 T/G cg01819863 chr10:32635814 EPC1 0.65 6.06 0.31 3.66e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg05484376 chr2:27715224 FNDC4 0.37 6.32 0.32 8.14e-10 Total body bone mineral density; LIHC cis rs4299518 0.516 rs12490293 chr3:45788127 T/C cg04837898 chr3:45731254 SACM1L 0.42 6.88 0.35 2.93e-11 Hirschsprung disease; LIHC cis rs6582630 0.638 rs7963994 chr12:38555535 G/A cg26384229 chr12:38710491 ALG10B -0.49 -6.81 -0.35 4.38e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs3736594 0.879 rs77154381 chr2:27982119 A/G cg27432699 chr2:27873401 GPN1 0.41 6.47 0.33 3.37e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC trans rs12599106 0.625 rs12923277 chr16:34896261 G/A cg18000306 chr6:288505 NA 0.34 6.2 0.32 1.64e-9 Menopause (age at onset); LIHC cis rs7772486 0.692 rs1577916 chr6:146069789 G/A cg05347473 chr6:146136440 FBXO30 -0.37 -5.99 -0.31 5.38e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs1986734 0.576 rs4624677 chr4:77420406 T/C cg24201034 chr4:77507246 SHROOM3 -0.38 -6.03 -0.31 4.19e-9 Eosinophilic esophagitis (pediatric);Metabolite levels (small molecules and protein measures); LIHC cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg18404041 chr3:52824283 ITIH1 -0.56 -9.15 -0.44 5.33e-18 Bipolar disorder; LIHC cis rs7072216 0.763 rs2274243 chr10:100175267 T/C cg26618903 chr10:100175079 PYROXD2 -0.4 -6.36 -0.33 6.29e-10 Metabolite levels; LIHC cis rs8180040 1.000 rs2302278 chr3:47361082 G/T cg16586182 chr3:47516702 SCAP 0.55 9.95 0.47 1.15e-20 Colorectal cancer; LIHC cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg22618164 chr12:122356400 WDR66 0.59 8.41 0.41 1.1e-15 Mean corpuscular volume; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg01411255 chr17:61851458 DDX42;CCDC47 1.0 21.48 0.76 2.11e-65 Height; LIHC cis rs6547741 0.904 rs1528403 chr2:27846645 C/G cg27432699 chr2:27873401 GPN1 0.72 11.01 0.51 2.5e-24 Oral cavity cancer; LIHC cis rs1008375 0.900 rs12650220 chr4:17595365 A/T cg16339924 chr4:17578868 LAP3 0.45 6.32 0.32 8.17e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4925386 0.840 rs6143034 chr20:60920545 T/C cg24112000 chr20:60950667 NA -0.45 -6.09 -0.31 2.95e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2573652 1.000 rs1469828 chr15:100517210 A/C cg09918751 chr15:100517450 ADAMTS17 -0.84 -16.22 -0.66 2.84e-44 Height; LIHC cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 11.24 0.52 3.81e-25 Platelet count; LIHC cis rs11628318 0.614 rs1190338 chr14:103105792 T/G cg12046867 chr14:103022105 NA -0.47 -6.79 -0.34 4.94e-11 Platelet count; LIHC cis rs896854 0.654 rs896846 chr8:95972453 G/A cg23172400 chr8:95962367 TP53INP1 -0.35 -7.83 -0.39 6.02e-14 Type 2 diabetes; LIHC cis rs9916302 0.851 rs4390625 chr17:37620347 A/G cg03013999 chr17:37608204 MED1 0.35 5.89 0.3 9.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs1712517 0.771 rs61350103 chr10:105069120 A/C cg05636881 chr10:105038444 INA 0.48 7.59 0.38 2.97e-13 Migraine; LIHC cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg13395646 chr4:1353034 KIAA1530 -0.68 -10.04 -0.48 5.7e-21 Obesity-related traits; LIHC cis rs910316 0.737 rs175510 chr14:75524839 G/A cg11812906 chr14:75593930 NEK9 -0.75 -14.06 -0.61 9.04e-36 Height; LIHC cis rs4654899 0.758 rs6668370 chr1:21369568 C/T cg08539965 chr1:21396338 EIF4G3 0.33 5.83 0.3 1.31e-8 Superior frontal gyrus grey matter volume; LIHC cis rs28374715 0.532 rs11854820 chr15:41676526 G/A cg18705301 chr15:41695430 NDUFAF1 -1.26 -18.85 -0.71 7.11e-55 Ulcerative colitis; LIHC cis rs12048904 0.541 rs1571046 chr1:101299216 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.45 6.38 0.33 5.7e-10 Multiple sclerosis; LIHC cis rs7666738 1.000 rs880471 chr4:98922541 C/T cg05340658 chr4:99064831 C4orf37 0.67 11.56 0.53 2.57e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs2070488 0.965 rs3762788 chr3:38493852 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 15.84 0.65 8.93e-43 Electrocardiographic conduction measures; LIHC cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.35 -0.32 6.92e-10 Gut microbiome composition (summer); LIHC cis rs4665809 0.878 rs6748745 chr2:26364190 C/T cg04944784 chr2:26401820 FAM59B -0.71 -9.01 -0.44 1.47e-17 Gut microbiome composition (summer); LIHC trans rs11098499 0.863 rs11736416 chr4:120431661 C/T cg25214090 chr10:38739885 LOC399744 0.59 9.55 0.46 2.59e-19 Corneal astigmatism; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23800573 chr21:45114399 RRP1B -0.4 -6.26 -0.32 1.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2479724 1.000 rs1536703 chr6:41852755 C/T cg17623882 chr6:41773611 USP49 -0.51 -7.58 -0.38 3.19e-13 Menarche (age at onset); LIHC cis rs7647973 1.000 rs7613491 chr3:49508976 T/C cg07636037 chr3:49044803 WDR6 -0.53 -6.46 -0.33 3.52e-10 Menarche (age at onset); LIHC cis rs1008375 0.966 rs10939736 chr4:17581617 T/A cg16339924 chr4:17578868 LAP3 0.46 6.31 0.32 8.79e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs67311347 0.524 rs11129869 chr3:40259738 G/A cg10755058 chr3:40428713 ENTPD3 0.35 5.75 0.3 1.95e-8 Renal cell carcinoma; LIHC cis rs6831352 0.589 rs2602836 chr4:100014805 C/T cg12011299 chr4:100065546 ADH4 -0.53 -11.88 -0.54 1.74e-27 Alcohol dependence; LIHC trans rs783540 0.967 rs1145173 chr15:83223425 A/G cg18393722 chr15:85113863 UBE2QP1 -0.43 -7.51 -0.38 5.31e-13 Schizophrenia; LIHC cis rs796364 1.000 rs71424239 chr2:200725473 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.65 -5.94 -0.31 7.09e-9 Schizophrenia; LIHC cis rs9858542 0.953 rs35261698 chr3:49537839 C/G cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs2180341 0.960 rs9398842 chr6:127674662 T/C cg24812749 chr6:127587940 RNF146 1.04 15.07 0.63 9.87e-40 Breast cancer; LIHC cis rs2228479 0.850 rs11641552 chr16:89838700 C/A cg14709524 chr16:89940631 TCF25 0.49 5.99 0.31 5.2e-9 Skin colour saturation; LIHC cis rs7258465 1.000 rs34171762 chr19:18559410 G/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.48 -0.38 6.19e-13 Breast cancer; LIHC cis rs919433 0.679 rs1902249 chr2:198521356 T/C cg03934865 chr2:198174659 NA 0.45 6.75 0.34 6.32e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7572733 0.534 rs4850813 chr2:198775982 C/T cg00792783 chr2:198669748 PLCL1 -0.46 -6.75 -0.34 6.3e-11 Dermatomyositis; LIHC cis rs7552404 0.655 rs5745336 chr1:76273519 G/A cg03433033 chr1:76189801 ACADM 0.58 7.29 0.37 2.23e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg03806693 chr22:41940476 POLR3H 1.06 12.64 0.56 2.63e-30 Vitiligo; LIHC cis rs763014 0.932 rs2384975 chr16:651115 G/T cg07343612 chr16:622815 PIGQ -0.85 -15.49 -0.64 2.21e-41 Height; LIHC cis rs600806 0.778 rs6693932 chr1:110003575 T/C cg11161837 chr1:110010384 SYPL2 0.47 6.15 0.32 2.17e-9 Intelligence (multi-trait analysis); LIHC cis rs7107174 0.688 rs2063725 chr11:78133452 T/G cg02023728 chr11:77925099 USP35 0.36 6.56 0.33 2.02e-10 Testicular germ cell tumor; LIHC cis rs7666738 0.606 rs7663216 chr4:99088385 A/C cg05340658 chr4:99064831 C4orf37 0.65 11.39 0.52 1.07e-25 Colonoscopy-negative controls vs population controls; LIHC cis rs16854884 0.586 rs7634145 chr3:143754150 G/A cg06585982 chr3:143692056 C3orf58 0.58 7.56 0.38 3.77e-13 Economic and political preferences (feminism/equality); LIHC cis rs1707322 1.000 rs7526369 chr1:46390560 G/C cg03146154 chr1:46216737 IPP 0.47 7.62 0.38 2.44e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01401336 chr17:2606734 KIAA0664 0.48 6.28 0.32 1e-9 Systolic blood pressure; LIHC cis rs941408 1.000 rs1640266 chr19:2787832 T/G cg06609049 chr19:2785107 THOP1 0.55 9.59 0.46 1.96e-19 Total cholesterol levels; LIHC cis rs6570726 0.791 rs9390336 chr6:145896823 A/T cg05347473 chr6:146136440 FBXO30 0.39 6.13 0.31 2.38e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11628318 0.614 rs7143783 chr14:103128751 A/G cg12046867 chr14:103022105 NA 0.5 7.24 0.36 3.01e-12 Platelet count; LIHC cis rs7188697 0.922 rs8047769 chr16:58591987 G/A cg02549819 chr16:58548995 SETD6 0.49 7.63 0.38 2.37e-13 QT interval; LIHC cis rs12477438 0.520 rs4850897 chr2:99768419 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.82 14.17 0.61 3.38e-36 Chronic sinus infection; LIHC cis rs1577917 0.958 rs114467802 chr6:86572350 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC cis rs7238033 0.663 rs11665385 chr18:43318746 A/G cg20610511 chr18:43302872 SLC14A1 -0.38 -6.34 -0.32 7.32e-10 Bladder cancer; LIHC trans rs875971 0.660 rs801192 chr7:66031952 C/G cg26939375 chr7:64535504 NA -0.43 -6.94 -0.35 2.02e-11 Aortic root size; LIHC cis rs933688 0.938 rs7705465 chr5:90680949 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.83 16.6 0.67 8.33e-46 Smoking behavior; LIHC cis rs11608355 0.545 rs12823587 chr12:109896390 A/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.35 0.41 1.76e-15 Height; LIHC cis rs826838 0.967 rs1352122 chr12:39130885 G/A cg13010199 chr12:38710504 ALG10B -0.4 -5.71 -0.3 2.43e-8 Heart rate; LIHC cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg09455208 chr3:40491958 NA 0.37 7.55 0.38 4.04e-13 Renal cell carcinoma; LIHC cis rs6582630 0.555 rs7301250 chr12:38596244 G/T cg26384229 chr12:38710491 ALG10B 0.9 11.57 0.53 2.38e-26 Drug-induced liver injury (flucloxacillin); LIHC cis rs11190604 1.000 rs2003284 chr10:102202338 A/G cg07080220 chr10:102295463 HIF1AN 0.48 6.82 0.35 4.11e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg09455208 chr3:40491958 NA 0.36 7.1 0.36 7.23e-12 Renal cell carcinoma; LIHC cis rs12477438 0.748 rs6712773 chr2:99585781 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -11.58 -0.53 2.12e-26 Chronic sinus infection; LIHC cis rs9911578 0.967 rs7222789 chr17:56819853 C/G cg12560992 chr17:57184187 TRIM37 0.96 17.17 0.68 4.27e-48 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs8176198 chr17:41230537 A/T cg05368731 chr17:41323189 NBR1 0.66 11.31 0.52 2.11e-25 Menopause (age at onset); LIHC cis rs7772486 0.777 rs1546966 chr6:146386018 G/T cg23711669 chr6:146136114 FBXO30 0.52 8.79 0.43 7.61e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs796364 0.806 rs12619136 chr2:200910347 C/A cg25936922 chr2:200820526 C2orf60;C2orf47 -0.67 -7.42 -0.37 9.56e-13 Schizophrenia; LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.87 0.78 6.99e-71 Height; LIHC cis rs12701220 0.894 rs12701406 chr7:1050283 G/A cg26769984 chr7:1090371 C7orf50 0.6 7.54 0.38 4.37e-13 Bronchopulmonary dysplasia; LIHC cis rs7635838 0.596 rs347598 chr3:11258289 G/C cg00170343 chr3:11313890 ATG7 0.56 8.88 0.43 3.72e-17 HDL cholesterol; LIHC cis rs2067615 0.579 rs3910854 chr12:107165669 T/C cg15890332 chr12:107067104 RFX4 0.26 6.02 0.31 4.5e-9 Heart rate; LIHC cis rs4969178 0.965 rs16971107 chr17:76394042 C/T cg20026190 chr17:76395443 PGS1 0.45 7.15 0.36 5.43e-12 HDL cholesterol levels; LIHC cis rs4911259 0.552 rs13042651 chr20:31467423 C/T cg13636640 chr20:31349939 DNMT3B -0.62 -10.85 -0.51 9.07e-24 Inflammatory bowel disease; LIHC trans rs941408 1.000 rs1076447 chr19:2792128 C/G cg19676328 chr12:49525230 TUBA1B -0.38 -6.13 -0.31 2.49e-9 Total cholesterol levels; LIHC cis rs2839186 0.605 rs2839170 chr21:47671305 A/G cg12016809 chr21:47604291 C21orf56 0.4 5.85 0.3 1.13e-8 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg00656387 chr3:40428638 ENTPD3 0.49 8.28 0.41 2.86e-15 Renal cell carcinoma; LIHC cis rs6570726 0.599 rs4398765 chr6:145935006 C/A cg05347473 chr6:146136440 FBXO30 0.41 5.74 0.3 2.08e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs2153535 0.580 rs2327050 chr6:8440630 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC trans rs1005277 0.579 rs2474571 chr10:38384639 T/G cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2016586 0.860 rs5995154 chr22:36102668 A/G cg26342177 chr22:36113512 APOL5 -0.38 -6.32 -0.32 8.08e-10 Body mass index; LIHC cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg00612595 chr21:47717864 NA -0.35 -5.81 -0.3 1.46e-8 Testicular germ cell tumor; LIHC cis rs1552244 0.882 rs17081288 chr3:10042113 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.77 10.36 0.49 4.53e-22 Alzheimer's disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01162549 chr5:141367464 RNF14 0.48 6.41 0.33 4.83e-10 Systolic blood pressure; LIHC cis rs1506636 1.000 rs1506636 chr7:123317140 C/T cg03229431 chr7:123269106 ASB15 0.6 12.05 0.55 4.17e-28 Plateletcrit;Platelet count; LIHC cis rs7503168 0.908 rs9897552 chr17:33974481 G/A cg20932281 chr17:33905541 PEX12 0.53 6.85 0.35 3.36e-11 Plateletcrit; LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg04267008 chr7:1944627 MAD1L1 0.6 9.27 0.45 2.11e-18 Bipolar disorder and schizophrenia; LIHC cis rs35110281 0.616 rs2236666 chr21:45109856 T/C cg04455712 chr21:45112962 RRP1B 0.54 8.96 0.44 2.07e-17 Mean corpuscular volume; LIHC cis rs56235845 0.694 rs9313758 chr5:176773091 T/G cg16006841 chr5:176797999 RGS14 0.57 7.69 0.38 1.55e-13 Hemoglobin concentration;Hematocrit; LIHC cis rs6584283 0.875 rs10748783 chr10:101285872 C/A cg06854084 chr10:101292507 NKX2-3 -0.33 -6.1 -0.31 2.87e-9 Ulcerative colitis; LIHC cis rs1552244 0.882 rs67895180 chr3:10026079 T/C cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs420259 0.727 rs35585 chr16:23677111 A/G cg05131483 chr16:23706242 ERN2 -0.35 -5.97 -0.31 5.93e-9 Bipolar disorder; LIHC cis rs12594515 1.000 rs11070467 chr15:45985001 C/T cg06207120 chr15:45996521 NA -0.33 -6.38 -0.33 5.75e-10 Waist circumference;Weight; LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.76 12.93 0.57 1.99e-31 Prudent dietary pattern; LIHC cis rs2274273 0.905 rs2075601 chr14:55609234 C/T cg01864836 chr14:55583639 NA -0.42 -8.19 -0.4 5.27e-15 Protein biomarker; LIHC cis rs9942416 0.660 rs17563686 chr5:74984818 A/T cg19683494 chr5:74908142 NA 0.57 7.55 0.38 3.91e-13 Age-related disease endophenotypes; LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg08677398 chr8:58056175 NA 0.41 6.3 0.32 9.4e-10 Developmental language disorder (linguistic errors); LIHC cis rs763121 0.925 rs5757165 chr22:38994577 C/T cg21395723 chr22:39101663 GTPBP1 0.37 6.28 0.32 1.06e-9 Menopause (age at onset); LIHC cis rs2070488 1.000 rs2268758 chr3:38514049 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.13 0.66 6.33e-44 Electrocardiographic conduction measures; LIHC trans rs3767633 0.925 rs2499855 chr1:161929761 C/T cg16753122 chr16:57506917 DOK4 0.67 6.22 0.32 1.45e-9 IgG glycosylation; LIHC cis rs6500602 0.727 rs4786516 chr16:4578641 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.93 0.31 7.59e-9 Schizophrenia; LIHC cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg07092213 chr7:1199455 ZFAND2A -0.47 -7.3 -0.37 2.04e-12 Longevity;Endometriosis; LIHC cis rs9549367 0.865 rs9549366 chr13:113907644 G/A cg00898013 chr13:113819073 PROZ -0.34 -6.21 -0.32 1.5e-9 Platelet distribution width; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg25461793 chr19:17212553 MYO9B 0.46 6.35 0.32 6.81e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC cis rs12477438 0.520 rs6756650 chr2:99801800 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.16 0.77 4.33e-68 Chronic sinus infection; LIHC cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg13699009 chr12:122356056 WDR66 0.6 9.03 0.44 1.3e-17 Mean corpuscular volume; LIHC cis rs920590 0.721 rs67989257 chr8:19660278 G/A cg03894339 chr8:19674705 INTS10 0.6 9.3 0.45 1.67e-18 Acute lymphoblastic leukemia (childhood); LIHC cis rs11868206 1 rs11868206 chr17:33959247 G/A cg05299278 chr17:33885742 SLFN14 -0.25 -5.75 -0.3 2.02e-8 Mean platelet volume; LIHC cis rs10489202 0.632 rs6659713 chr1:168072249 G/T cg24449463 chr1:168025552 DCAF6 0.52 8.2 0.41 4.85e-15 Schizophrenia; LIHC cis rs16828019 0.852 rs12408956 chr1:41651952 G/A cg03962019 chr1:41807865 NA 0.53 7.53 0.38 4.66e-13 Intelligence (multi-trait analysis); LIHC cis rs7408868 1.000 rs757475 chr19:15273749 C/T cg14696996 chr19:15285081 NOTCH3 0.53 6.99 0.35 1.45e-11 Pulse pressure; LIHC cis rs1564271 1.000 rs1197422 chr10:27012078 A/G cg13837822 chr10:26931731 LOC731789 0.33 6.09 0.31 2.96e-9 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC trans rs6759952 0.649 rs1382435 chr2:218296003 A/G cg02325880 chr1:84971750 SPATA1;GNG5 0.35 6.04 0.31 3.98e-9 Thyroid cancer; LIHC cis rs7212590 0.618 rs35806089 chr17:57943906 A/G cg10252138 chr17:58120427 NA -0.62 -6.58 -0.34 1.74e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs2841277 0.771 rs2819469 chr14:105394859 G/A cg21017887 chr14:105400489 NA -0.65 -11.62 -0.53 1.51e-26 Rheumatoid arthritis; LIHC cis rs655641 0.954 rs595972 chr11:85705885 G/T cg09030501 chr11:85779252 PICALM -0.51 -6.11 -0.31 2.75e-9 Platelet count; LIHC trans rs6717918 0.517 rs2633263 chr2:233127453 T/C cg19760917 chr1:2411643 PLCH2 -0.4 -6.24 -0.32 1.29e-9 Height; LIHC cis rs9486715 0.867 rs9384628 chr6:96960232 T/C cg06623918 chr6:96969491 KIAA0776 0.86 15.21 0.64 2.93e-40 Headache; LIHC cis rs10256972 0.640 rs10271082 chr7:1081562 G/C cg16145915 chr7:1198662 ZFAND2A -0.28 -6.78 -0.34 5.27e-11 Longevity;Endometriosis; LIHC cis rs8060686 0.545 rs9931987 chr16:68256639 G/A cg09835421 chr16:68378352 PRMT7 -0.49 -5.87 -0.3 1.01e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs11098499 0.779 rs7699346 chr4:120310542 C/T cg09307838 chr4:120376055 NA 0.75 11.49 0.53 4.46e-26 Corneal astigmatism; LIHC cis rs9640161 0.830 rs17173681 chr7:150059414 A/G cg10018233 chr7:150070692 REPIN1 -0.67 -12.35 -0.56 3.22e-29 Blood protein levels;Circulating chemerin levels; LIHC cis rs71327718 1 rs71327718 chr3:125592857 C/G cg05084668 chr3:125655381 ALG1L -0.73 -9.41 -0.45 7.48e-19 Metabolite levels (HVA/5-HIAA ratio); LIHC cis rs6754311 0.731 rs2236783 chr2:136594158 G/A cg07169764 chr2:136633963 MCM6 -0.66 -9.82 -0.47 3.14e-20 Mosquito bite size; LIHC cis rs3106136 0.678 rs7680426 chr4:95294837 G/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.98 0.31 5.48e-9 Capecitabine sensitivity; LIHC cis rs2279817 0.863 rs12749985 chr1:18026004 C/T cg21791023 chr1:18019539 ARHGEF10L -0.39 -6.2 -0.32 1.64e-9 Neuroticism; LIHC cis rs17401966 1.000 rs7520651 chr1:10329872 G/A cg15208524 chr1:10270712 KIF1B 0.45 6.47 0.33 3.3e-10 Hepatocellular carcinoma; LIHC cis rs6500602 0.598 rs3859155 chr16:4593741 A/C cg08645402 chr16:4508243 NA -0.36 -6.58 -0.34 1.79e-10 Schizophrenia; LIHC cis rs4700695 0.841 rs251304 chr5:65249700 A/G cg21114390 chr5:65439923 SFRS12 0.44 5.77 0.3 1.8e-8 Facial morphology (factor 19); LIHC cis rs1865721 0.958 rs57073257 chr18:73172316 A/G cg26385618 chr18:73139727 C18orf62 -0.29 -7.33 -0.37 1.64e-12 Intelligence; LIHC cis rs7592578 0.664 rs10931461 chr2:191405280 T/A cg27211696 chr2:191398769 TMEM194B 0.63 8.35 0.41 1.72e-15 Diastolic blood pressure; LIHC cis rs798554 1.000 rs798554 chr7:2759795 C/T cg19346786 chr7:2764209 NA -0.44 -6.52 -0.33 2.59e-10 Height; LIHC cis rs10193935 0.901 rs13393459 chr2:42463124 C/T cg27598129 chr2:42591480 NA -0.72 -10.51 -0.49 1.46e-22 Colonoscopy-negative controls vs population controls; LIHC cis rs2257205 0.667 rs73996262 chr17:56784426 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -6.56 -0.33 2e-10 Pancreatic cancer; LIHC cis rs7267979 0.932 rs372678 chr20:25465248 G/A cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.8 0.35 4.7e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg06481639 chr22:41940642 POLR3H 0.69 6.97 0.35 1.67e-11 Vitiligo; LIHC cis rs7772486 0.875 rs13198450 chr6:146370524 C/A cg13319975 chr6:146136371 FBXO30 -0.36 -6.0 -0.31 5.05e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7647973 1.000 rs6446268 chr3:49445695 G/A cg07636037 chr3:49044803 WDR6 -0.53 -6.41 -0.33 4.79e-10 Menarche (age at onset); LIHC cis rs10751667 0.643 rs10794350 chr11:946070 A/G ch.11.42038R chr11:967971 AP2A2 0.55 10.03 0.48 6.16e-21 Alzheimer's disease (late onset); LIHC cis rs7582720 1.000 rs72934711 chr2:203709997 G/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.03 0.31 4.27e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg07308232 chr7:1071921 C7orf50 -0.4 -6.49 -0.33 3.01e-10 Longevity;Endometriosis; LIHC cis rs769267 0.965 rs8101938 chr19:19390497 G/A cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs611744 0.967 rs2600614 chr8:109198079 T/A cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.65e-11 Dupuytren's disease; LIHC cis rs1878931 0.582 rs10048083 chr16:3417465 A/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.67 9.0 0.44 1.6e-17 Body mass index (adult); LIHC cis rs2071426 0.959 rs12359863 chr10:96812230 C/T cg09036531 chr10:96991505 NA -0.5 -5.78 -0.3 1.66e-8 Blood metabolite levels; LIHC cis rs2797160 1.000 rs6569435 chr6:125998186 T/C cg05901451 chr6:126070800 HEY2 -0.4 -6.95 -0.35 1.84e-11 Endometrial cancer; LIHC cis rs4595586 0.525 rs35089392 chr12:39414547 T/G cg26384229 chr12:38710491 ALG10B 0.51 6.05 0.31 3.8e-9 Morning vs. evening chronotype; LIHC cis rs7592578 0.679 rs4287794 chr2:191327147 T/C cg10560079 chr2:191398806 TMEM194B -0.78 -11.18 -0.52 6.09e-25 Diastolic blood pressure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg06109949 chr2:178937838 PDE11A 0.41 7.01 0.35 1.29e-11 Cognitive function; LIHC cis rs57590327 0.508 rs9820349 chr3:81958587 A/G cg07356753 chr3:81810745 GBE1 -0.53 -8.3 -0.41 2.45e-15 Extraversion; LIHC cis rs7264396 0.563 rs2050729 chr20:34294409 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.62 8.7 0.43 1.45e-16 Total cholesterol levels; LIHC cis rs7512552 0.839 rs486275 chr1:150282784 G/A cg15654264 chr1:150340011 RPRD2 -0.68 -11.67 -0.53 9.93e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs9768139 0.733 rs71545585 chr7:158118672 G/A cg06219351 chr7:158114137 PTPRN2 -0.21 -5.98 -0.31 5.74e-9 Calcium levels; LIHC cis rs7208859 0.623 rs3794796 chr17:29130880 G/C cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs826838 1.000 rs10880914 chr12:38720543 C/T cg26384229 chr12:38710491 ALG10B 1.06 14.86 0.63 6.89e-39 Heart rate; LIHC cis rs763121 0.853 rs5750664 chr22:39072769 C/T cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs9733 0.596 rs11204697 chr1:150658971 C/T cg13175981 chr1:150552382 MCL1 -0.44 -6.11 -0.31 2.68e-9 Tonsillectomy; LIHC cis rs2073499 1.000 rs2073498 chr3:50369546 C/A cg12708802 chr3:50388878 TUSC4;CYB561D2 0.69 7.02 0.35 1.23e-11 Schizophrenia; LIHC cis rs992157 0.661 rs17653757 chr2:219109364 G/C cg20019365 chr2:219134978 PNKD;AAMP 0.8 13.61 0.59 5.31e-34 Colorectal cancer; LIHC cis rs5769765 0.954 rs6009900 chr22:50236610 T/C cg02269571 chr22:50332266 NA -0.64 -8.68 -0.42 1.7e-16 Schizophrenia; LIHC cis rs8017423 0.967 rs60548738 chr14:90724399 G/A cg14092571 chr14:90743983 NA -0.39 -6.16 -0.32 2.02e-9 Mortality in heart failure; LIHC cis rs6430585 0.591 rs77096272 chr2:136663605 C/A cg07169764 chr2:136633963 MCM6 1.29 21.37 0.76 5.86e-65 Corneal structure; LIHC cis rs9649213 0.593 rs12704982 chr7:97926053 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.77 -0.3 1.82e-8 Prostate cancer (SNP x SNP interaction); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg14394617 chr12:54674541 HNRNPA1;HNRPA1L-2;CBX5 -0.41 -6.45 -0.33 3.9e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs3768617 0.565 rs4652775 chr1:183061825 A/T ch.1.3577855R chr1:183094577 LAMC1 0.6 10.33 0.49 5.94e-22 Fuchs's corneal dystrophy; LIHC cis rs1144333 1.000 rs1021464 chr1:76375415 G/A cg03433033 chr1:76189801 ACADM 0.54 8.03 0.4 1.61e-14 Attention function in attention deficit hyperactive disorder; LIHC cis rs10791097 0.678 rs10894272 chr11:130731081 A/G cg14779329 chr11:130786720 SNX19 0.37 5.81 0.3 1.41e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7772486 0.641 rs67882056 chr6:146416301 T/C cg05347473 chr6:146136440 FBXO30 0.44 6.5 0.33 2.82e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs9399135 0.967 rs12526055 chr6:135325918 C/T cg22676075 chr6:135203613 NA 0.39 6.3 0.32 9.37e-10 Red blood cell count; LIHC cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg23131131 chr22:24373011 LOC391322 -0.71 -10.62 -0.5 6.05e-23 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg09497769 chr2:24248384 NA 0.48 6.4 0.33 5.14e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs78456975 1.000 rs28742145 chr2:1562671 T/C cg01028140 chr2:1542097 TPO -0.53 -6.4 -0.33 5.21e-10 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs2839186 0.934 rs2839194 chr21:47699437 T/G cg12379764 chr21:47803548 PCNT -0.6 -8.77 -0.43 8.27e-17 Testicular germ cell tumor; LIHC cis rs9811920 0.609 rs6809988 chr3:99656615 A/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.42 -5.99 -0.31 5.2e-9 Axial length; LIHC cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.61 12.19 0.55 1.21e-28 Prudent dietary pattern; LIHC cis rs7512552 0.809 rs1694377 chr1:150293153 A/G cg15654264 chr1:150340011 RPRD2 0.7 11.94 0.54 1.05e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs34172651 0.517 rs11642954 chr16:24824248 G/A cg00152838 chr16:24741724 TNRC6A -0.53 -6.41 -0.33 4.95e-10 Intelligence (multi-trait analysis); LIHC cis rs7131987 0.650 rs3782509 chr12:29453778 G/A cg12903224 chr12:29470962 FAR2 -0.4 -6.56 -0.33 2.04e-10 QT interval; LIHC cis rs6062302 0.522 rs2872810 chr20:62241931 C/T cg06363034 chr20:62225388 GMEB2 0.44 7.65 0.38 2.01e-13 Glioblastoma; LIHC cis rs7918232 0.941 rs1085782 chr10:27440517 G/A cg14240646 chr10:27532245 ACBD5 0.68 6.32 0.32 8.3e-10 Breast cancer; LIHC cis rs765787 0.530 rs1706764 chr15:45524256 T/A cg25801113 chr15:45476975 SHF 0.37 6.33 0.32 7.88e-10 Uric acid levels; LIHC cis rs7552167 0.925 rs11249020 chr1:24512804 A/G cg01960748 chr1:24522592 NA -0.79 -9.38 -0.45 9.21e-19 Psoriasis vulgaris; LIHC cis rs9902453 0.791 rs3098950 chr17:27998385 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.22 0.58 1.62e-32 Coffee consumption (cups per day); LIHC cis rs67478160 0.634 rs2368558 chr14:104230518 A/G cg08213375 chr14:104286397 PPP1R13B 0.52 10.07 0.48 4.6e-21 Schizophrenia; LIHC cis rs782590 0.935 rs10460508 chr2:55882565 A/C cg18811423 chr2:55921094 PNPT1 0.86 13.63 0.59 4.52e-34 Metabolic syndrome; LIHC trans rs12692119 0.655 rs7421909 chr2:127655310 C/A cg13995918 chr5:1280305 TERT -0.46 -6.42 -0.33 4.63e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs10508774 1.000 rs9971245 chr10:32754413 C/T cg01819863 chr10:32635814 EPC1 0.65 6.08 0.31 3.26e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9916302 0.706 rs597069 chr17:37458512 G/T cg07936489 chr17:37558343 FBXL20 0.85 12.2 0.55 1.1e-28 Glomerular filtration rate (creatinine); LIHC trans rs10213084 0.915 rs13115523 chr4:147510610 A/G cg18061433 chr10:21435895 C10orf113;NEBL 0.47 6.04 0.31 3.94e-9 Heart rate; LIHC cis rs7647973 1.000 rs9862534 chr3:49598064 A/G cg07636037 chr3:49044803 WDR6 0.5 6.5 0.33 2.92e-10 Menarche (age at onset); LIHC cis rs7635838 0.718 rs2248971 chr3:11403441 T/C cg00170343 chr3:11313890 ATG7 0.49 7.78 0.39 8.57e-14 HDL cholesterol; LIHC cis rs7937682 0.883 rs2212520 chr11:111462096 C/T cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs2235642 0.750 rs2859310 chr16:1656765 C/T cg03034668 chr16:1723424 CRAMP1L 0.4 7.15 0.36 5.24e-12 Coronary artery disease; LIHC cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg08888203 chr3:10149979 C3orf24 0.62 5.76 0.3 1.86e-8 Alzheimer's disease; LIHC cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs13108904 0.518 rs4974603 chr4:1343168 C/T cg22903657 chr4:1355424 KIAA1530 -0.44 -6.55 -0.33 2.1e-10 Obesity-related traits; LIHC cis rs6690583 0.573 rs75119114 chr1:85451385 A/C cg22153463 chr1:85462885 MCOLN2 0.52 6.22 0.32 1.42e-9 Serum sulfate level; LIHC cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.72 12.48 0.56 1.05e-29 Colorectal cancer; LIHC cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg05368731 chr17:41323189 NBR1 0.73 12.45 0.56 1.39e-29 Menopause (age at onset); LIHC cis rs11628318 0.617 rs11626481 chr14:103086356 A/G cg23461800 chr14:103021989 NA -0.45 -5.92 -0.31 7.69e-9 Platelet count; LIHC cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 0.69 9.92 0.47 1.44e-20 Lymphocyte counts; LIHC cis rs1707322 1.000 rs12403666 chr1:46431621 G/A cg03146154 chr1:46216737 IPP 0.48 7.68 0.38 1.64e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg23054440 chr19:41169017 NA -0.49 -6.09 -0.31 3e-9 Systolic blood pressure; LIHC cis rs1552244 0.882 rs13088350 chr3:10044626 T/C cg08888203 chr3:10149979 C3orf24 0.46 6.01 0.31 4.75e-9 Alzheimer's disease; LIHC cis rs2228479 0.850 rs11645240 chr16:89837326 T/C cg06558623 chr16:89946397 TCF25 0.86 11.95 0.54 9.45e-28 Skin colour saturation; LIHC cis rs4589502 0.800 rs12595796 chr15:67202599 A/G cg09911534 chr15:67153556 NA 0.44 6.8 0.35 4.62e-11 Lung cancer (smoking interaction); LIHC cis rs769267 0.930 rs6511038 chr19:19607564 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.98 0.4 2.19e-14 Tonsillectomy; LIHC cis rs2803122 0.502 rs1854552 chr9:19235047 C/T cg13469590 chr9:19229767 NA 0.37 6.22 0.32 1.42e-9 Pulse pressure; LIHC cis rs4808199 1.000 rs60321073 chr19:19499598 A/G cg03709012 chr19:19516395 GATAD2A 1.09 19.42 0.72 3.96e-57 Nonalcoholic fatty liver disease; LIHC cis rs7961581 0.957 rs1353362 chr12:71613276 C/T cg05756094 chr12:71608604 NA 0.37 5.81 0.3 1.46e-8 Type 2 diabetes; LIHC trans rs11098499 0.754 rs10213554 chr4:120260785 A/G cg25214090 chr10:38739885 LOC399744 -0.5 -8.25 -0.41 3.53e-15 Corneal astigmatism; LIHC cis rs6714710 0.603 rs78006955 chr2:98455510 G/C cg26665480 chr2:98280029 ACTR1B 0.45 6.27 0.32 1.06e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs559928 0.606 rs12417635 chr11:63912728 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 7.46 0.37 7.18e-13 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7512552 0.803 rs9435997 chr1:150289496 G/A cg15654264 chr1:150340011 RPRD2 -0.69 -11.79 -0.54 3.72e-27 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs5753618 0.561 rs9609264 chr22:31746719 C/G cg22777020 chr22:31556080 RNF185 0.56 6.45 0.33 3.85e-10 Colorectal cancer; LIHC trans rs6058796 0.892 rs6141782 chr20:31263507 A/G cg02600331 chr11:130417168 NA 0.34 7.6 0.38 2.85e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; LIHC cis rs916888 0.821 rs199505 chr17:44859410 A/G cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg09455208 chr3:40491958 NA -0.36 -7.13 -0.36 5.83e-12 Renal cell carcinoma; LIHC cis rs3780378 1.000 rs10815158 chr9:5112844 G/A cg02405213 chr9:5042618 JAK2 -0.48 -8.61 -0.42 2.68e-16 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg22979624 chr14:90863808 CALM1 0.41 6.27 0.32 1.1e-9 Morning vs. evening chronotype; LIHC cis rs3008870 1.000 rs4620509 chr1:67449941 A/G cg02640540 chr1:67518911 SLC35D1 -0.42 -5.85 -0.3 1.17e-8 Lymphocyte percentage of white cells; LIHC cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg18252515 chr7:66147081 NA 1.27 16.64 0.67 5.59e-46 Diabetic kidney disease; LIHC cis rs7772486 0.727 rs10447449 chr6:146138707 A/G cg05347473 chr6:146136440 FBXO30 0.36 5.88 0.3 9.58e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg11890956 chr21:40555474 PSMG1 -1.0 -14.22 -0.61 2.21e-36 Cognitive function; LIHC cis rs911119 0.913 rs6036461 chr20:23576754 C/G cg16589663 chr20:23618590 CST3 0.66 6.99 0.35 1.45e-11 Chronic kidney disease; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs7551222 0.752 rs4245737 chr1:204486242 A/G cg20240347 chr1:204465584 NA -0.36 -7.59 -0.38 3.01e-13 Schizophrenia; LIHC cis rs7945718 0.839 rs11022512 chr11:12835952 G/A cg25843174 chr11:12811716 TEAD1 0.36 8.33 0.41 2e-15 Educational attainment (years of education); LIHC cis rs826838 1.000 rs11168217 chr12:38884278 T/C cg13010199 chr12:38710504 ALG10B 0.61 7.49 0.38 6.09e-13 Heart rate; LIHC cis rs7959452 0.640 rs12370042 chr12:69692420 C/G cg20891283 chr12:69753455 YEATS4 0.81 15.5 0.64 2.02e-41 Blood protein levels; LIHC cis rs798554 0.757 rs2533879 chr7:2859847 G/A cg13628971 chr7:2884303 GNA12 0.57 8.17 0.4 6.11e-15 Height; LIHC cis rs7903847 0.642 rs11189180 chr10:99143529 A/G cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7762018 1.000 rs4716380 chr6:170090399 A/G cg13891659 chr6:170190454 C6orf122;C6orf208 0.49 5.74 0.3 2.04e-8 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs2629540 0.824 rs10901809 chr10:126410804 C/T cg20435097 chr10:126320824 FAM53B -0.41 -6.46 -0.33 3.61e-10 Cocaine dependence; LIHC cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.81 -0.35 4.43e-11 Menopause (age at onset); LIHC cis rs4268898 0.636 rs9636438 chr2:24460566 C/T cg06627628 chr2:24431161 ITSN2 0.73 9.86 0.47 2.33e-20 Asthma; LIHC trans rs13113518 0.812 rs11932712 chr4:56302590 C/T cg15358633 chr12:38710606 ALG10B 0.44 6.29 0.32 9.6e-10 Height; LIHC cis rs3857067 0.806 rs11943926 chr4:95136512 G/A cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.48 -0.37 6.49e-13 QT interval; LIHC cis rs10870270 0.957 rs3829156 chr10:133789386 C/G cg17892150 chr10:133769511 PPP2R2D -0.64 -11.57 -0.53 2.43e-26 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs17253792 0.545 rs34719936 chr14:56015134 G/A cg01858014 chr14:56050164 KTN1 -0.63 -5.87 -0.3 1.03e-8 Putamen volume; LIHC cis rs882732 0.576 rs2068790 chr14:95033944 C/T cg14866387 chr14:95027382 SERPINA4 0.38 6.13 0.31 2.41e-9 Blood protein levels; LIHC cis rs9381040 0.655 rs9394756 chr6:41016183 A/G cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -6.02 -0.31 4.56e-9 Alzheimer's disease (late onset); LIHC cis rs10097731 0.901 rs10464891 chr8:82042900 C/A cg25230327 chr8:82042993 NA -0.59 -8.01 -0.4 1.81e-14 Serum total protein level; LIHC cis rs3749237 0.595 rs885592 chr3:49497883 T/G cg02487422 chr3:49467188 NICN1 0.42 6.55 0.33 2.16e-10 Resting heart rate; LIHC cis rs12594515 1.000 rs6493170 chr15:45987019 G/A cg06207120 chr15:45996521 NA 0.34 6.62 0.34 1.4e-10 Waist circumference;Weight; LIHC cis rs7208859 0.623 rs34756112 chr17:29113016 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11711311 0.955 rs67550112 chr3:113401988 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.39 6.58 0.34 1.8e-10 IgG glycosylation; LIHC cis rs1799949 0.930 rs2298861 chr17:41176831 G/A cg05368731 chr17:41323189 NBR1 0.74 12.61 0.56 3.38e-30 Menopause (age at onset); LIHC cis rs3213545 0.700 rs2260445 chr12:121468863 C/A cg15155738 chr12:121454335 C12orf43 0.46 6.62 0.34 1.36e-10 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg05368731 chr17:41323189 NBR1 0.73 12.66 0.56 2.17e-30 Menopause (age at onset); LIHC cis rs919433 0.680 rs7568250 chr2:198409611 G/A cg03934865 chr2:198174659 NA 0.55 8.37 0.41 1.46e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs3008870 1.000 rs6673462 chr1:67461857 A/C cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs6121246 0.909 rs57726761 chr20:30314046 A/G cg13852791 chr20:30311386 BCL2L1 0.96 9.74 0.47 6.05e-20 Mean corpuscular hemoglobin; LIHC cis rs847649 1.000 rs847649 chr7:102556011 C/T cg18108683 chr7:102477205 FBXL13 -0.49 -7.36 -0.37 1.38e-12 Morning vs. evening chronotype; LIHC cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg12310025 chr6:25882481 NA -0.63 -8.89 -0.43 3.66e-17 Blood metabolite levels; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg22387756 chr11:1495050 HCCA2 -0.42 -6.12 -0.31 2.57e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs1005277 0.502 rs2800484 chr10:38542415 C/T cg27523141 chr10:43048294 ZNF37B 0.4 6.76 0.34 6.02e-11 Extrinsic epigenetic age acceleration; LIHC cis rs1552244 0.554 rs17050704 chr3:10045734 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01423368 chr11:76155379 C11orf30 0.42 6.43 0.33 4.33e-10 Cognitive function; LIHC cis rs2075371 1.000 rs2598292 chr7:133988584 C/G cg11752832 chr7:134001865 SLC35B4 0.51 7.78 0.39 8.45e-14 Mean platelet volume; LIHC cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg06466757 chr4:1255808 NA 0.34 5.72 0.3 2.38e-8 Obesity-related traits; LIHC cis rs67311347 1.000 rs4973898 chr3:40459532 A/G cg00656387 chr3:40428638 ENTPD3 -0.45 -7.69 -0.38 1.59e-13 Renal cell carcinoma; LIHC cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg20607798 chr8:58055168 NA 0.49 6.0 0.31 5.08e-9 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04604666 chr4:37828046 PGM2 0.46 6.25 0.32 1.24e-9 Pancreatic cancer; LIHC cis rs611744 0.805 rs453634 chr8:109135101 T/C cg21045802 chr8:109455806 TTC35 0.5 8.48 0.42 6.86e-16 Dupuytren's disease; LIHC cis rs778371 0.723 rs737027 chr2:233641083 G/C cg08000102 chr2:233561755 GIGYF2 0.88 14.7 0.62 2.93e-38 Schizophrenia; LIHC cis rs7762018 0.891 rs12529402 chr6:170147675 A/T cg13891659 chr6:170190454 C6orf122;C6orf208 0.55 6.77 0.34 5.71e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs6696846 0.765 rs2836 chr1:205111761 G/T cg21545522 chr1:205238299 TMCC2 -0.35 -6.6 -0.34 1.61e-10 Red blood cell count; LIHC cis rs9733 0.596 rs72702523 chr1:150650425 G/T cg13175981 chr1:150552382 MCL1 -0.44 -6.13 -0.31 2.43e-9 Tonsillectomy; LIHC cis rs3768617 1.000 rs12026314 chr1:183104527 A/G ch.1.3577855R chr1:183094577 LAMC1 0.47 7.9 0.39 3.83e-14 Fuchs's corneal dystrophy; LIHC cis rs79976124 0.842 rs74881738 chr6:66621825 T/G cg07460842 chr6:66804631 NA 0.65 6.96 0.35 1.77e-11 Type 2 diabetes; LIHC cis rs875971 0.862 rs4718383 chr7:66108409 T/C cg11764359 chr7:65958608 NA -0.71 -11.86 -0.54 2.06e-27 Aortic root size; LIHC cis rs7666738 0.830 rs6854919 chr4:98947326 C/T cg05340658 chr4:99064831 C4orf37 0.7 12.29 0.55 5.14e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.47 0.46 4.67e-19 Bipolar disorder; LIHC cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg22800045 chr5:56110881 MAP3K1 -0.57 -6.79 -0.34 4.89e-11 Initial pursuit acceleration; LIHC cis rs295140 0.605 rs3739119 chr2:201194279 C/A cg23649088 chr2:200775458 C2orf69 -0.45 -6.16 -0.32 2.01e-9 QT interval; LIHC cis rs1552244 0.882 rs13062917 chr3:10017032 T/A cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs9896933 0.667 rs2253131 chr17:80696547 T/A cg20578329 chr17:80767326 TBCD -0.72 -7.21 -0.36 3.62e-12 Bone mineral accretion in asthma (oral corticosteroid dose interaction); LIHC cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg11279151 chr3:101281821 RG9MTD1 0.38 5.86 0.3 1.12e-8 Colorectal cancer; LIHC cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg24675658 chr1:53192096 ZYG11B 0.63 10.23 0.48 1.29e-21 Monocyte count; LIHC cis rs7107174 1.000 rs7101429 chr11:77992967 A/G cg02023728 chr11:77925099 USP35 0.52 10.06 0.48 5.17e-21 Testicular germ cell tumor; LIHC trans rs7246657 0.882 rs13345148 chr19:37819631 A/G cg24637308 chr11:6592297 DNHD1 0.44 6.19 0.32 1.68e-9 Coronary artery calcification; LIHC cis rs896854 0.738 rs481887 chr8:95967838 A/G cg13393036 chr8:95962371 TP53INP1 0.38 7.63 0.38 2.41e-13 Type 2 diabetes; LIHC cis rs9303401 0.527 rs12939313 chr17:56755616 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.98 12.18 0.55 1.41e-28 Cognitive test performance; LIHC cis rs4638749 0.677 rs4676186 chr2:108842640 T/C cg06795125 chr2:108905320 SULT1C2 -0.3 -5.96 -0.31 6.23e-9 Blood pressure; LIHC cis rs116095464 0.558 rs10079760 chr5:230778 A/G cg22857025 chr5:266934 NA -1.4 -16.88 -0.67 6.21e-47 Breast cancer; LIHC cis rs7772486 0.840 rs2474355 chr6:146312540 C/G cg13319975 chr6:146136371 FBXO30 -0.4 -6.47 -0.33 3.31e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7238033 0.624 rs8087241 chr18:43309703 G/A cg20610511 chr18:43302872 SLC14A1 0.39 6.53 0.33 2.41e-10 Bladder cancer; LIHC cis rs1395 0.778 rs56364136 chr2:27451429 T/C cg23587288 chr2:27483067 SLC30A3 -0.29 -5.74 -0.3 2.08e-8 Blood metabolite levels; LIHC cis rs2834256 0.527 rs9983901 chr21:34866853 C/T cg14850771 chr21:34775459 IFNGR2 0.47 7.77 0.39 9.31e-14 Red cell distribution width; LIHC cis rs116095464 0.510 rs73016876 chr5:244475 T/C cg22857025 chr5:266934 NA -1.47 -17.56 -0.69 1.16e-49 Breast cancer; LIHC cis rs11583043 0.958 rs11583674 chr1:101396560 C/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 9.52 0.46 3.1400000000000002e-19 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.78 0.62 1.38e-38 Prudent dietary pattern; LIHC cis rs9303401 0.659 rs35797125 chr17:56736547 G/A cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs796364 0.664 rs4673660 chr2:200915395 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.56 6.85 0.35 3.41e-11 Schizophrenia; LIHC cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg10755058 chr3:40428713 ENTPD3 -0.42 -7.25 -0.36 2.8e-12 Renal cell carcinoma; LIHC cis rs2071426 0.959 rs1934982 chr10:96802124 A/C cg09036531 chr10:96991505 NA -0.49 -5.84 -0.3 1.22e-8 Blood metabolite levels; LIHC cis rs6466055 0.692 rs4727621 chr7:105028370 T/C cg04380332 chr7:105027541 SRPK2 -0.38 -7.03 -0.36 1.14e-11 Schizophrenia; LIHC cis rs13126513 0.708 rs4368610 chr4:100453746 G/T cg05468953 chr4:100565104 NA 0.34 6.32 0.32 8.1e-10 Metabolite levels (MHPG); LIHC cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg02353165 chr6:42928485 GNMT 0.77 11.75 0.54 5.06e-27 Alzheimer's disease in APOE e4+ carriers; LIHC trans rs10506458 0.915 rs998506 chr12:63400017 C/T cg22491629 chr6:157744540 C6orf35 -0.61 -10.93 -0.51 4.6e-24 Hemostatic factors and hematological phenotypes; LIHC cis rs716804 0.740 rs7118500 chr11:10284762 C/A cg01453529 chr11:10209919 SBF2 -0.29 -5.74 -0.3 2.13e-8 Neuroticism; LIHC cis rs1005277 0.579 rs2474580 chr10:38398713 G/A cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs6973256 0.569 rs6944149 chr7:133381365 A/C cg03336402 chr7:133662267 EXOC4 -0.37 -5.78 -0.3 1.66e-8 Intelligence (multi-trait analysis); LIHC cis rs2979489 0.891 rs2915624 chr8:30381245 T/C cg26383811 chr8:30366931 RBPMS -0.7 -11.0 -0.51 2.72e-24 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs3008870 0.959 rs2985826 chr1:67412918 G/C cg02640540 chr1:67518911 SLC35D1 0.42 5.8 0.3 1.5e-8 Lymphocyte percentage of white cells; LIHC cis rs6088590 1.000 rs6088615 chr20:33400474 C/T cg24642439 chr20:33292090 TP53INP2 -0.72 -9.88 -0.47 2.1e-20 Coronary artery disease; LIHC cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg16325326 chr1:53192061 ZYG11B -0.49 -8.64 -0.42 2.22e-16 Monocyte count; LIHC cis rs12477438 0.871 rs62156364 chr2:99695097 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.7 -9.33 -0.45 1.38e-18 Chronic sinus infection; LIHC cis rs6088813 1.000 rs4911180 chr20:33972948 G/A cg14752227 chr20:34000481 UQCC -0.41 -5.89 -0.3 9.11e-9 Height; LIHC cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg10096929 chr1:156261403 TMEM79 0.4 6.66 0.34 1.08e-10 Tonsillectomy; LIHC cis rs244293 0.965 rs244364 chr17:53188280 C/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.54 -0.38 4.36e-13 Menarche (age at onset); LIHC cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg24531977 chr5:56204891 C5orf35 -0.66 -9.46 -0.46 5.25e-19 Initial pursuit acceleration; LIHC cis rs7819412 0.595 rs10106914 chr8:10987651 T/G cg21775007 chr8:11205619 TDH -0.46 -5.72 -0.3 2.31e-8 Triglycerides; LIHC cis rs1789 0.903 rs4616746 chr4:15673098 A/G cg16509355 chr4:15471240 CC2D2A -0.46 -7.02 -0.35 1.23e-11 Blood protein levels; LIHC cis rs7089973 0.604 rs11196942 chr10:116596872 G/A cg03647239 chr10:116582469 FAM160B1 0.46 6.66 0.34 1.11e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs4819052 0.851 rs7279182 chr21:46656112 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 10.18 0.48 1.91e-21 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs1419980 0.673 rs10772553 chr12:7768089 G/A cg25828445 chr12:7781288 NA -0.41 -6.31 -0.32 8.62e-10 HDL cholesterol levels; LIHC cis rs9733 0.519 rs10788792 chr1:150638572 T/G cg13175981 chr1:150552382 MCL1 -0.43 -5.9 -0.3 8.63e-9 Tonsillectomy; LIHC cis rs2832191 0.967 rs2251377 chr21:30530599 T/C cg08807101 chr21:30365312 RNF160 0.54 8.38 0.41 1.38e-15 Dental caries; LIHC cis rs769267 0.965 rs2023882 chr19:19405405 T/C cg21559469 chr19:19431446 KIAA0892;SF4 0.41 5.74 0.3 2.09e-8 Tonsillectomy; LIHC cis rs2842992 0.662 rs2273825 chr6:160211424 A/C cg11366901 chr6:160182831 ACAT2 0.86 14.38 0.61 5.22e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg06453172 chr10:134556979 INPP5A -0.65 -8.23 -0.41 4.09e-15 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4407350 1.000 rs4823330 chr22:44923080 G/A cg26276947 chr22:44892394 LDOC1L 0.33 6.01 0.31 4.83e-9 Intelligence (multi-trait analysis); LIHC trans rs6912958 0.712 rs9444526 chr6:88326402 A/G cg23605328 chr1:201951606 RNPEP 0.39 6.23 0.32 1.36e-9 Monocyte percentage of white cells; LIHC cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg23758822 chr17:41437982 NA -0.87 -16.72 -0.67 2.82e-46 Menopause (age at onset); LIHC cis rs9929218 0.859 rs9936682 chr16:68748223 A/G cg01231543 chr16:68741748 NA 0.39 5.98 0.31 5.58e-9 Colorectal cancer; LIHC cis rs4853012 0.838 rs60964317 chr2:74343423 A/T cg19729930 chr2:74357872 NA 0.81 17.71 0.69 3e-50 Gestational age at birth (maternal effect); LIHC cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg13126279 chr21:47581558 C21orf56 -0.44 -7.07 -0.36 8.74e-12 Testicular germ cell tumor; LIHC cis rs7772486 0.790 rs80050589 chr6:146230454 T/C cg13319975 chr6:146136371 FBXO30 0.38 6.15 0.32 2.17e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9828933 0.752 rs73117082 chr3:63947565 A/G cg16258503 chr3:63850278 ATXN7;THOC7 -0.79 -10.05 -0.48 5.57e-21 Type 2 diabetes; LIHC cis rs3806843 1.000 rs9686540 chr5:140174622 G/A cg26395211 chr5:140044315 WDR55 -0.43 -6.43 -0.33 4.19e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg17691542 chr6:26056736 HIST1H1C 0.4 6.03 0.31 4.2e-9 Height; LIHC cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg13395646 chr4:1353034 KIAA1530 -0.51 -8.38 -0.41 1.41e-15 Obesity-related traits; LIHC cis rs929354 0.772 rs2023977 chr7:156996022 C/G cg05182265 chr7:156933206 UBE3C -0.32 -6.05 -0.31 3.82e-9 Body mass index; LIHC cis rs2635047 0.967 rs2571016 chr18:44639175 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -6.38 -0.33 5.92e-10 Educational attainment; LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.02 24.41 0.8 6.42e-77 Prudent dietary pattern; LIHC cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg26338869 chr17:61819248 STRADA 0.52 7.0 0.35 1.34e-11 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg14519123 chr15:66544965 MEGF11 0.45 6.33 0.32 7.87e-10 Lung function (FEV1/FVC); LIHC cis rs6964587 1.000 rs6974607 chr7:91750116 G/A cg17063962 chr7:91808500 NA 1.02 19.6 0.73 7.06e-58 Breast cancer; LIHC cis rs919433 0.713 rs6714697 chr2:198484486 C/T cg10820045 chr2:198174542 NA 0.51 7.99 0.4 2.06e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs6762 0.748 rs5030780 chr11:838110 C/T cg15787769 chr11:842744 TSPAN4;POLR2L -0.64 -7.89 -0.39 4.22e-14 Mean platelet volume; LIHC cis rs875971 0.767 rs1643394 chr7:65836094 A/G cg18252515 chr7:66147081 NA -0.43 -6.22 -0.32 1.46e-9 Aortic root size; LIHC cis rs908922 0.676 rs1538083 chr1:152517116 A/G cg20991723 chr1:152506922 NA 0.53 9.05 0.44 1.09e-17 Hair morphology; LIHC cis rs253664 0.898 rs1199347 chr3:138083361 T/C cg17918682 chr3:137893718 DBR1 -0.54 -5.72 -0.3 2.38e-8 Body mass index; LIHC cis rs1198430 0.714 rs1198437 chr1:23747424 G/C cg13183780 chr1:23809682 ASAP3 -0.37 -6.47 -0.33 3.33e-10 Total cholesterol levels; LIHC cis rs17376456 0.825 rs36042718 chr5:93180997 C/T cg25358565 chr5:93447407 FAM172A 1.08 9.74 0.47 5.89e-20 Diabetic retinopathy; LIHC cis rs240764 0.658 rs2132169 chr6:101177663 C/A cg09795085 chr6:101329169 ASCC3 -0.52 -7.29 -0.37 2.19e-12 Neuroticism; LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg14004847 chr7:1930337 MAD1L1 -0.47 -6.8 -0.35 4.62e-11 Bipolar disorder and schizophrenia; LIHC cis rs892961 0.899 rs312911 chr17:75414585 A/C cg05865280 chr17:75406074 SEPT9 0.61 15.65 0.65 5.01e-42 Airflow obstruction; LIHC cis rs10751667 0.621 rs7394681 chr11:952111 C/T cg06064525 chr11:970664 AP2A2 -0.56 -15.01 -0.63 1.81e-39 Alzheimer's disease (late onset); LIHC cis rs9896052 0.649 rs6501797 chr17:73444312 G/A cg25649188 chr17:73499917 CASKIN2 0.44 6.9 0.35 2.52e-11 Sight-threatening diabetic retinopathy in type 2 diabetes; LIHC cis rs6138458 0.816 rs2151463 chr20:24911819 A/C cg26195577 chr20:24973756 C20orf3 1.13 14.83 0.63 9.14e-39 Blood protein levels; LIHC trans rs8073060 0.614 rs72829932 chr17:34055935 A/G cg19694781 chr19:47549865 TMEM160 1.22 12.74 0.57 1.12e-30 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7224737 1.000 rs9912088 chr17:40288278 T/C cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs5758659 1.000 rs134882 chr22:42670965 A/G cg19513890 chr22:42538836 CYP2D7P1 -0.37 -7.07 -0.36 8.87e-12 Cognitive function; LIHC cis rs7769051 0.522 rs62424539 chr6:133173272 C/T cg22852734 chr6:133119734 C6orf192 0.76 6.6 0.34 1.56e-10 Type 2 diabetes nephropathy; LIHC cis rs17376456 0.877 rs13165147 chr5:93422214 G/A cg25358565 chr5:93447407 FAM172A 1.14 10.5 0.49 1.59e-22 Diabetic retinopathy; LIHC cis rs17685 0.753 rs10264760 chr7:75749694 A/G cg01364799 chr7:75623366 TMEM120A -0.48 -7.34 -0.37 1.59e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9583531 0.600 rs2119479 chr13:111371181 A/C cg24331049 chr13:111365604 ING1 0.8 13.46 0.59 1.89e-33 Coronary artery disease; LIHC cis rs4474465 0.920 rs10793321 chr11:78237566 A/G cg27205649 chr11:78285834 NARS2 0.4 5.96 0.31 6.28e-9 Alzheimer's disease (survival time); LIHC cis rs1005277 0.579 rs2474571 chr10:38384639 T/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs992157 0.798 rs4674284 chr2:219161241 C/T cg00012203 chr2:219082015 ARPC2 -0.84 -13.47 -0.59 1.84e-33 Colorectal cancer; LIHC cis rs754466 0.580 rs12357670 chr10:79558180 T/C cg17075019 chr10:79541650 NA -0.8 -12.37 -0.56 2.56e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs6840360 1.000 rs4696104 chr4:152600451 A/G cg22705602 chr4:152727874 NA -0.3 -6.43 -0.33 4.42e-10 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.563 rs997147 chr21:40695325 A/G cg06238570 chr21:40685208 BRWD1 -0.53 -8.74 -0.43 1.1e-16 Cognitive function; LIHC cis rs2153535 0.541 rs9379207 chr6:8458186 C/T cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs876084 0.505 rs10216978 chr8:121105620 C/A cg06265175 chr8:121136014 COL14A1 0.48 7.94 0.39 2.88e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6831352 0.918 rs34071486 chr4:100051087 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs6120849 0.754 rs11167253 chr20:33614449 T/C cg24642439 chr20:33292090 TP53INP2 0.65 7.0 0.35 1.36e-11 Protein C levels; LIHC cis rs908922 0.651 rs10888493 chr1:152503913 G/A cg23254163 chr1:152506842 NA 0.22 5.77 0.3 1.75e-8 Hair morphology; LIHC cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg08048268 chr3:133502702 NA -0.43 -6.63 -0.34 1.3100000000000001e-10 Iron status biomarkers; LIHC cis rs1055129 0.560 rs2608880 chr17:73938957 C/T cg10935138 chr17:73851978 WBP2 0.49 7.31 0.37 1.96e-12 White matter hyperintensity burden; LIHC cis rs7534824 0.625 rs10493939 chr1:101378026 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.73 6.97 0.35 1.6e-11 Refractive astigmatism; LIHC cis rs60012524 1 rs60012524 chr2:99559117 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.76 -7.59 -0.38 3.15e-13 Chronic sinus infection; LIHC cis rs8180040 0.522 rs749512 chr3:47035900 C/T cg16586182 chr3:47516702 SCAP 0.47 8.15 0.4 7.01e-15 Colorectal cancer; LIHC cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.55 8.75 0.43 1.02e-16 Schizophrenia; LIHC cis rs12744310 1.000 rs34796305 chr1:41769045 A/G cg03962019 chr1:41807865 NA 0.39 6.36 0.33 6.56e-10 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7927592 0.913 rs12272917 chr11:68263370 T/C cg16797656 chr11:68205561 LRP5 0.53 8.33 0.41 1.92e-15 Total body bone mineral density; LIHC cis rs7095607 0.730 rs1900012 chr10:69953942 G/A cg18986048 chr10:69913749 MYPN 0.43 6.53 0.33 2.36e-10 Lung function (FVC); LIHC cis rs2576037 0.526 rs11082562 chr18:44522671 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 10.81 0.5 1.3e-23 Personality dimensions; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21576300 chr4:124107741 SPATA5 0.28 6.04 0.31 4.04e-9 Cognitive function; LIHC trans rs17685 0.753 rs1639617 chr7:75701728 A/G cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg07424592 chr7:64974309 NA 0.76 8.63 0.42 2.3e-16 Diabetic kidney disease; LIHC cis rs12142240 0.698 rs13374893 chr1:46843800 A/G cg14993813 chr1:46806288 NSUN4 -0.64 -5.78 -0.3 1.66e-8 Menopause (age at onset); LIHC cis rs9326248 1.000 rs3736120 chr11:117032125 G/T cg01368799 chr11:117014884 PAFAH1B2 0.47 6.63 0.34 1.32e-10 Blood protein levels; LIHC cis rs7589728 0.925 rs78829281 chr2:88502293 T/A cg04511125 chr2:88470314 THNSL2 0.88 8.5 0.42 6.12e-16 Plasma clusterin levels; LIHC cis rs3806843 0.966 rs2240693 chr5:140183325 G/C cg26395211 chr5:140044315 WDR55 -0.42 -6.22 -0.32 1.47e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.73 0.39 1.19e-13 Bipolar disorder; LIHC cis rs35883536 0.605 rs2133118 chr1:101034337 C/T cg14515779 chr1:101123966 NA 0.42 5.75 0.3 2.02e-8 Monocyte count; LIHC cis rs2576037 0.526 rs4890707 chr18:44497724 C/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.69 11.04 0.51 1.93e-24 Personality dimensions; LIHC cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg11235426 chr6:292522 DUSP22 -0.53 -7.14 -0.36 5.61e-12 Menopause (age at onset); LIHC cis rs3749237 0.964 rs2234385 chr3:49846041 G/A cg03060546 chr3:49711283 APEH 0.37 5.9 0.3 8.53e-9 Resting heart rate; LIHC trans rs4566648 0.593 rs6825902 chr4:84174111 G/C cg06219686 chr17:29421884 NF1 -0.52 -6.12 -0.31 2.53e-9 Monocyte count; LIHC cis rs860295 0.541 rs11264359 chr1:155282829 A/G cg02153340 chr1:155202674 NA -0.35 -6.33 -0.32 7.59e-10 Body mass index; LIHC trans rs1814175 0.692 rs1851873 chr11:49937767 A/G cg03929089 chr4:120376271 NA -0.6 -9.94 -0.47 1.28e-20 Height; LIHC cis rs2180341 1.000 rs6904520 chr6:127629802 T/C cg27446573 chr6:127587934 RNF146 1.03 16.06 0.66 1.17e-43 Breast cancer; LIHC cis rs9372253 0.678 rs6568644 chr6:110707820 C/T cg19196401 chr6:110721138 DDO -0.33 -6.55 -0.33 2.07e-10 Platelet distribution width; LIHC cis rs7923837 0.687 rs1977833 chr10:94463945 G/A cg25506282 chr10:94462361 NA 0.37 6.57 0.33 1.88e-10 Body mass index;Multiple sclerosis; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.73 10.76 0.5 1.88e-23 Lymphocyte counts; LIHC cis rs9918079 0.560 rs4698409 chr4:15659766 G/A cg16509355 chr4:15471240 CC2D2A -0.45 -7.0 -0.35 1.39e-11 Obesity-related traits; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg10755058 chr3:40428713 ENTPD3 0.4 6.78 0.34 5.32e-11 Renal cell carcinoma; LIHC cis rs67311347 0.955 rs9821036 chr3:40379007 A/G cg09455208 chr3:40491958 NA 0.34 6.63 0.34 1.32e-10 Renal cell carcinoma; LIHC cis rs9399137 0.507 rs6569986 chr6:135311641 T/C cg24558204 chr6:135376177 HBS1L 0.61 10.36 0.49 4.63e-22 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs9783347 1.000 rs4150655 chr11:18375164 A/T cg15585147 chr11:18324498 HPS5 -0.43 -7.07 -0.36 8.7e-12 Pancreatic cancer; LIHC cis rs7617773 1.000 rs6442108 chr3:48192959 G/C cg11946769 chr3:48343235 NME6 -0.65 -8.39 -0.41 1.34e-15 Coronary artery disease; LIHC cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg25894440 chr7:65020034 NA 0.53 6.07 0.31 3.34e-9 Diabetic kidney disease; LIHC cis rs5770917 1.000 rs1056964 chr22:51017476 A/G cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.4 -5.91 -0.3 8.28e-9 Narcolepsy; LIHC cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.58 8.9 0.43 3.34e-17 Height; LIHC trans rs2243480 1.000 rs60683927 chr7:65394768 T/C cg10756647 chr7:56101905 PSPH 1.09 13.61 0.59 5.4e-34 Diabetic kidney disease; LIHC cis rs66573146 0.572 rs66819208 chr4:6946128 A/G cg00086871 chr4:6988644 TBC1D14 0.79 6.02 0.31 4.58e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs968567 0.559 rs174548 chr11:61571348 C/G cg27386326 chr11:61587980 NA 0.71 15.28 0.64 1.56e-40 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs2439831 1.000 rs690436 chr15:43761205 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.79 0.43 7.64e-17 Lung cancer in ever smokers; LIHC cis rs9926296 0.656 rs11861084 chr16:89875710 G/T cg27121462 chr16:89883253 FANCA -0.37 -5.86 -0.3 1.1e-8 Vitiligo; LIHC cis rs28830936 0.966 rs890505 chr15:42129158 G/A cg17847044 chr15:42102381 MAPKBP1 -0.3 -6.16 -0.32 2.02e-9 Diastolic blood pressure; LIHC cis rs11864453 0.611 rs1050361 chr16:72130203 C/G cg16558253 chr16:72132732 DHX38 -0.45 -7.31 -0.37 1.95e-12 Fibrinogen levels; LIHC cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.48 -7.27 -0.37 2.39e-12 Tuberculosis; LIHC cis rs748404 0.723 rs11853991 chr15:43557549 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.39 5.96 0.31 6.13e-9 Lung cancer; LIHC cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg08280861 chr8:58055591 NA 0.52 6.33 0.32 7.52e-10 Developmental language disorder (linguistic errors); LIHC cis rs4555082 0.834 rs11849607 chr14:105745383 G/A cg06808227 chr14:105710500 BRF1 -0.55 -7.18 -0.36 4.31e-12 Mean platelet volume;Platelet distribution width; LIHC cis rs6545883 0.826 rs2694651 chr2:61588642 T/C cg14146966 chr2:61757674 XPO1 -0.43 -7.23 -0.36 3.28e-12 Tuberculosis; LIHC cis rs4820539 1.000 rs4822362 chr22:23482744 C/A cg14186256 chr22:23484241 RTDR1 0.94 19.93 0.73 3.27e-59 Bone mineral density; LIHC cis rs10256972 1.000 rs10256972 chr7:1039003 G/T cg16145915 chr7:1198662 ZFAND2A 0.29 7.1 0.36 7.22e-12 Longevity;Endometriosis; LIHC cis rs7551222 0.752 rs10793765 chr1:204549375 A/G cg20240347 chr1:204465584 NA -0.36 -7.24 -0.36 3e-12 Schizophrenia; LIHC cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.32 5.86 0.3 1.12e-8 Calcium levels; LIHC cis rs273218 1.000 rs156440 chr5:53373656 A/T ch.5.1024479R chr5:53302184 ARL15 0.67 10.96 0.51 3.84e-24 Migraine; LIHC cis rs332507 0.601 rs4677939 chr3:124374405 A/C cg05980111 chr3:124395277 KALRN 0.32 6.21 0.32 1.57e-9 Plateletcrit; LIHC cis rs1165668 0.959 rs2576954 chr12:104312254 C/T cg21863207 chr12:104234989 NT5DC3 0.4 6.39 0.33 5.27e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs8177179 0.967 rs6782434 chr3:133438834 C/G cg24879335 chr3:133465180 TF 0.48 11.09 0.51 1.31e-24 Iron status biomarkers (transferrin levels); LIHC trans rs11098499 0.865 rs9996417 chr4:120295862 T/C cg25214090 chr10:38739885 LOC399744 0.55 8.64 0.42 2.27e-16 Corneal astigmatism; LIHC cis rs780096 0.526 rs2010087 chr2:27637235 C/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.89 -0.3 9.2e-9 Total body bone mineral density; LIHC cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.39 -8.47 -0.42 7.53e-16 Calcium levels; LIHC cis rs763014 0.932 rs2384972 chr16:674424 G/A cg09256448 chr16:638327 NA 0.38 6.25 0.32 1.25e-9 Height; LIHC cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.68 0.46 9.5e-20 Bipolar disorder; LIHC trans rs6598955 0.671 rs11247905 chr1:26627907 G/C cg07461501 chr17:79650226 HGS;ARL16 -0.74 -8.23 -0.41 3.96e-15 Obesity-related traits; LIHC cis rs35306767 0.904 rs10904584 chr10:983747 A/T cg20503657 chr10:835505 NA 0.87 10.02 0.48 6.8e-21 Eosinophil percentage of granulocytes; LIHC cis rs5753037 0.809 rs5763512 chr22:30212366 C/T cg01021169 chr22:30184971 ASCC2 -0.37 -7.01 -0.35 1.25e-11 Type 1 diabetes; LIHC cis rs7872515 0.887 rs28727560 chr9:94864754 A/C cg01248375 chr9:94877805 SPTLC1 0.54 8.06 0.4 1.26e-14 Bipolar disorder and schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08484479 chr5:887419 BRD9 0.45 6.52 0.33 2.5e-10 Longevity; LIHC cis rs16828019 0.852 rs34286980 chr1:41608389 A/G cg03962019 chr1:41807865 NA 0.53 7.51 0.38 5.27e-13 Intelligence (multi-trait analysis); LIHC cis rs1008375 1.000 rs28545485 chr4:17645376 C/T cg15017067 chr4:17643749 FAM184B 0.34 5.9 0.3 8.54e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs765787 0.530 rs2554456 chr15:45521138 A/C cg24006582 chr15:45444508 DUOX1 -0.52 -7.5 -0.38 5.55e-13 Uric acid levels; LIHC cis rs7572733 0.534 rs700674 chr2:198693703 C/T cg03934865 chr2:198174659 NA 0.45 6.53 0.33 2.35e-10 Dermatomyositis; LIHC cis rs9649465 0.542 rs616297 chr7:123426949 A/G cg03229431 chr7:123269106 ASB15 0.43 9.16 0.44 5e-18 Migraine; LIHC cis rs7264396 0.635 rs6060688 chr20:34516731 C/G cg04508476 chr20:34239394 CPNE1;RBM12 0.64 10.58 0.5 8.09e-23 Total cholesterol levels; LIHC cis rs6714710 0.603 rs35505530 chr2:98506910 T/C cg26665480 chr2:98280029 ACTR1B 0.44 6.2 0.32 1.64e-9 Posterior cortical atrophy and Alzheimer's disease; LIHC cis rs9303401 0.659 rs35564417 chr17:56718286 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.91 12.32 0.55 4.06e-29 Cognitive test performance; LIHC cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs1619021 chr17:37739274 G/A cg03013999 chr17:37608204 MED1 0.36 5.9 0.3 8.86e-9 Glomerular filtration rate (creatinine); LIHC cis rs2997447 0.846 rs12071062 chr1:26412199 T/G cg19633962 chr1:26362018 EXTL1 -0.59 -6.93 -0.35 2.09e-11 QRS complex (12-leadsum); LIHC cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.45e-11 Diabetic kidney disease; LIHC cis rs4689592 0.503 rs59640165 chr4:7051661 G/A cg19539972 chr4:7069911 GRPEL1 -0.68 -9.42 -0.45 7.14e-19 Monocyte percentage of white cells; LIHC trans rs66573146 0.831 rs73088564 chr4:6984553 G/C cg07817883 chr1:32538562 TMEM39B 1.1 9.14 0.44 5.78e-18 Granulocyte percentage of myeloid white cells; LIHC cis rs7662987 0.517 rs2851277 chr4:100022910 G/T cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs477692 0.905 rs524545 chr10:131411840 A/C cg05714579 chr10:131428358 MGMT -0.5 -8.52 -0.42 5.07e-16 Response to temozolomide; LIHC cis rs763014 0.966 rs4984904 chr16:680809 C/G cg07343612 chr16:622815 PIGQ -0.86 -14.96 -0.63 2.86e-39 Height; LIHC cis rs7927592 0.956 rs7104877 chr11:68377602 G/T cg01657329 chr11:68192670 LRP5 0.48 6.33 0.32 7.69e-10 Total body bone mineral density; LIHC trans rs7246657 0.943 rs6508733 chr19:38000548 A/T cg10208301 chr11:6592745 DNHD1 0.45 6.38 0.33 5.86e-10 Coronary artery calcification; LIHC cis rs986417 1.000 rs1116854 chr14:60917496 C/A cg27398547 chr14:60952738 C14orf39 -0.81 -9.56 -0.46 2.38e-19 Gut microbiota (bacterial taxa); LIHC cis rs780096 0.546 rs4425043 chr2:27733452 G/A cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -6.07 -0.31 3.31e-9 Total body bone mineral density; LIHC cis rs12477438 0.677 rs12475034 chr2:99699464 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.71 -9.14 -0.44 5.78e-18 Chronic sinus infection; LIHC cis rs1552244 0.572 rs2054478 chr3:10172211 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 8.9 0.43 3.43e-17 Alzheimer's disease; LIHC cis rs16958440 1.000 rs60228288 chr18:44640412 G/A cg17192377 chr18:44677553 HDHD2 0.61 6.84 0.35 3.55e-11 Sitting height ratio; LIHC cis rs4650994 0.593 rs10753180 chr1:178520653 A/G cg05350800 chr1:178550844 NA -0.33 -7.36 -0.37 1.37e-12 HDL cholesterol levels;HDL cholesterol; LIHC cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg02475777 chr4:1388615 CRIPAK 0.54 8.1 0.4 9.65e-15 Longevity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22958951 chr11:119252637 USP2 0.46 6.13 0.31 2.39e-9 Pancreatic cancer; LIHC cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 5.88 0.3 9.86e-9 Menopause (age at onset); LIHC cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg03806693 chr22:41940476 POLR3H -1.04 -12.19 -0.55 1.27e-28 Vitiligo; LIHC cis rs9916302 0.861 rs644173 chr17:37430519 T/C cg00129232 chr17:37814104 STARD3 -0.4 -6.35 -0.32 6.69e-10 Glomerular filtration rate (creatinine); LIHC cis rs748404 0.697 rs475227 chr15:43546446 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.34 0.41 1.87e-15 Lung cancer; LIHC cis rs7927771 1.000 rs34910028 chr11:47758449 T/C cg20307385 chr11:47447363 PSMC3 -0.44 -5.8 -0.3 1.55e-8 Subjective well-being; LIHC cis rs2839627 0.638 rs7276320 chr21:44269588 A/G cg03543861 chr21:44258195 NA -0.59 -8.09 -0.4 1.02e-14 Information processing speed; LIHC cis rs1419980 0.730 rs7132326 chr12:7752391 G/T cg10578777 chr12:7781093 NA -0.4 -5.79 -0.3 1.59e-8 HDL cholesterol levels; LIHC cis rs4788570 0.578 rs4788553 chr16:71780277 T/G cg06353428 chr16:71660113 MARVELD3 1.41 15.66 0.65 4.68e-42 Intelligence (multi-trait analysis); LIHC cis rs2070488 0.775 rs762318 chr3:38516369 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.76 12.56 0.56 4.97e-30 Electrocardiographic conduction measures; LIHC cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg13047869 chr3:10149882 C3orf24 0.51 6.16 0.32 2.02e-9 Alzheimer's disease; LIHC cis rs9549367 0.774 rs2287246 chr13:113889127 A/G cg18105134 chr13:113819100 PROZ -0.67 -11.68 -0.53 9.56e-27 Platelet distribution width; LIHC cis rs66573146 0.572 rs67750430 chr4:6957266 T/G cg00086871 chr4:6988644 TBC1D14 0.79 6.07 0.31 3.3e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs1395 0.710 rs11674947 chr2:27471996 A/G cg23587288 chr2:27483067 SLC30A3 -0.34 -6.44 -0.33 3.94e-10 Blood metabolite levels; LIHC cis rs7659604 0.502 rs10013916 chr4:122702179 T/G cg19671926 chr4:122722719 EXOSC9 0.54 8.48 0.42 7.02e-16 Type 2 diabetes; LIHC cis rs2370759 1.000 rs11594459 chr10:32561858 A/C cg01819863 chr10:32635814 EPC1 1.11 16.57 0.67 1.07e-45 Sexual dysfunction (female); LIHC cis rs7089973 0.604 rs11819372 chr10:116594934 A/G cg23260525 chr10:116636907 FAM160B1 0.38 7.66 0.38 1.88e-13 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs6582630 0.555 rs10785454 chr12:38476260 C/T cg13010199 chr12:38710504 ALG10B 0.46 6.14 0.31 2.35e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs903552 0.866 rs11247296 chr15:102007919 T/C cg00659931 chr15:102010125 PCSK6 -0.49 -6.83 -0.35 3.9e-11 Diabetic kidney disease; LIHC cis rs6963495 0.818 rs117845382 chr7:105152040 T/C cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs1005277 0.579 rs2474595 chr10:38426782 C/G cg03665457 chr10:38645376 HSD17B7P2 0.39 5.73 0.3 2.23e-8 Extrinsic epigenetic age acceleration; LIHC cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg12311346 chr5:56204834 C5orf35 -0.56 -7.31 -0.37 1.89e-12 Initial pursuit acceleration; LIHC trans rs208520 0.690 rs2797693 chr6:66868985 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.77 -8.44 -0.42 9.43e-16 Exhaled nitric oxide output; LIHC cis rs7772486 0.686 rs2179323 chr6:145982786 T/G cg23711669 chr6:146136114 FBXO30 -0.63 -11.2 -0.52 5.28e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs13191362 1.000 rs73008453 chr6:163013384 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.63 5.92 0.3 7.72e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1577917 1.000 rs12215903 chr6:86675028 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.44 -0.33 4.12e-10 Response to antipsychotic treatment; LIHC cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -11.92 -0.54 1.19e-27 Alzheimer's disease; LIHC cis rs4713118 0.662 rs149961 chr6:28015569 A/C cg16479474 chr6:28041457 NA 0.47 7.17 0.36 4.71e-12 Parkinson's disease; LIHC cis rs1982963 1.000 rs753050 chr14:52505375 A/G cg10843707 chr14:52510701 NID2 -0.44 -7.7 -0.38 1.51e-13 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs7615952 0.611 rs7632305 chr3:125634767 C/T cg05084668 chr3:125655381 ALG1L -0.81 -10.6 -0.5 6.61e-23 Blood pressure (smoking interaction); LIHC cis rs11098499 0.722 rs28713555 chr4:120251995 C/T cg09307838 chr4:120376055 NA 0.71 11.02 0.51 2.19e-24 Corneal astigmatism; LIHC cis rs9814567 1.000 rs7432268 chr3:134242051 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.77 -0.3 1.78e-8 Menopause (age at onset); LIHC cis rs244293 0.931 rs173408 chr17:53202392 G/A cg19360675 chr17:53046073 COX11;STXBP4 -0.51 -7.58 -0.38 3.24e-13 Menarche (age at onset); LIHC cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs7917772 0.565 rs1043450 chr10:104434209 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.71 8.61 0.42 2.77e-16 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg06481639 chr22:41940642 POLR3H 0.7 7.28 0.37 2.38e-12 Vitiligo; LIHC cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.59 8.45 0.42 8.72e-16 Lymphocyte counts; LIHC cis rs1552244 0.554 rs2272122 chr3:10047975 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -7.13 -0.36 5.91e-12 Alzheimer's disease; LIHC cis rs11864453 0.713 rs9925763 chr16:72142595 C/A cg16558253 chr16:72132732 DHX38 -0.47 -7.46 -0.37 6.99e-13 Fibrinogen levels; LIHC cis rs2576037 0.523 rs1539881 chr18:44477897 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 11.0 0.51 2.66e-24 Personality dimensions; LIHC cis rs6121246 0.821 rs115585940 chr20:30317902 T/C cg13852791 chr20:30311386 BCL2L1 0.89 8.53 0.42 4.9e-16 Mean corpuscular hemoglobin; LIHC cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -11.92 -0.54 1.19e-27 Alzheimer's disease; LIHC cis rs3736485 0.934 rs17609791 chr15:51874824 C/T cg08986416 chr15:51914746 DMXL2 -0.42 -6.33 -0.32 7.72e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1538970 0.962 rs7532762 chr1:45864695 C/A cg24296786 chr1:45957014 TESK2 -0.52 -7.85 -0.39 5.52e-14 Platelet count; LIHC cis rs12144094 0.882 rs10494229 chr1:120229117 A/G cg20995928 chr1:120229863 NA 0.41 7.17 0.36 4.77e-12 Height; LIHC cis rs2758596 1.000 rs2736608 chr1:156180349 T/A cg24450063 chr1:156163899 SLC25A44 0.99 9.99 0.48 8.94e-21 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs17685 0.725 rs7795291 chr7:75725206 C/A cg04610667 chr7:75704037 NA -0.33 -5.92 -0.3 8.04e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9457247 0.935 rs1794697 chr6:167395410 C/T cg12798992 chr6:167411361 FGFR1OP 0.59 9.71 0.46 7.83e-20 Crohn's disease; LIHC cis rs9470366 0.527 rs733590 chr6:36645203 A/G cg08179530 chr6:36648295 CDKN1A 0.6 9.24 0.45 2.63e-18 QRS duration; LIHC trans rs1814175 0.645 rs28436748 chr11:50046422 G/A cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs763121 0.853 rs5750672 chr22:39104168 C/T cg06022373 chr22:39101656 GTPBP1 -0.67 -11.62 -0.53 1.56e-26 Menopause (age at onset); LIHC cis rs7635838 0.653 rs2606749 chr3:11373635 A/G cg00170343 chr3:11313890 ATG7 0.6 10.07 0.48 4.79e-21 HDL cholesterol; LIHC cis rs2073300 0.609 rs8183135 chr20:23384284 C/T cg16736954 chr20:23401023 NAPB 0.71 8.28 0.41 2.86e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs734999 0.545 rs41300092 chr1:2537838 C/T cg18854424 chr1:2615690 NA 0.32 7.06 0.36 9.14e-12 Ulcerative colitis; LIHC cis rs9486719 1.000 rs2499807 chr6:96864053 T/G cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs2404618 0.534 rs2214861 chr8:1490604 A/G cg22787604 chr8:1509810 DLGAP2 -0.42 -7.48 -0.37 6.36e-13 Lung cancer; LIHC cis rs17401966 0.522 rs4845930 chr1:10319049 G/A cg19773385 chr1:10388646 KIF1B -0.33 -6.05 -0.31 3.75e-9 Hepatocellular carcinoma; LIHC cis rs7587476 0.601 rs17489231 chr2:215673739 T/G cg04530015 chr2:215796436 ABCA12 0.46 7.75 0.39 1.08e-13 Neuroblastoma; LIHC cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg05590025 chr7:65112418 INTS4L2 0.44 6.58 0.34 1.79e-10 Calcium levels; LIHC cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 13.0 0.58 1.11e-31 Prudent dietary pattern; LIHC cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.99 -20.46 -0.74 2.56e-61 Height; LIHC cis rs11971779 0.650 rs10085842 chr7:139064582 A/G cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg06873352 chr17:61820015 STRADA 0.72 12.63 0.56 2.87e-30 Prudent dietary pattern; LIHC cis rs6426558 0.559 rs7549520 chr1:227258858 G/C cg10327440 chr1:227177885 CDC42BPA 0.44 6.77 0.34 5.65e-11 Neutrophil percentage of white cells; LIHC cis rs9682041 0.688 rs7621787 chr3:170146862 T/A cg11886554 chr3:170076028 SKIL 0.93 6.46 0.33 3.62e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs7572733 0.555 rs2341778 chr2:198776546 G/A cg00792783 chr2:198669748 PLCL1 -0.46 -6.75 -0.34 6.3e-11 Dermatomyositis; LIHC trans rs7874142 0.616 rs4842167 chr9:137687314 A/G cg18109838 chr5:88185987 MEF2C 0.37 7.65 0.38 2.09e-13 Longevity; LIHC cis rs9902453 0.845 rs2259855 chr17:28097860 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -11.8 -0.54 3.43e-27 Coffee consumption (cups per day); LIHC cis rs769267 0.965 rs8103496 chr19:19386015 A/G cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs11864453 0.826 rs9941087 chr16:72118324 G/A cg01557791 chr16:72042693 DHODH -0.52 -8.47 -0.42 7.59e-16 Fibrinogen levels; LIHC cis rs12908161 1.000 rs12911736 chr15:85240008 A/G cg03959625 chr15:84868606 LOC388152 0.42 5.91 0.3 8.27e-9 Schizophrenia; LIHC cis rs17685 0.712 rs1639620 chr7:75704090 A/G cg04592579 chr7:75616294 TMEM120A 0.4 6.95 0.35 1.84e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg13395646 chr4:1353034 KIAA1530 -0.63 -8.96 -0.44 2.09e-17 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg25009327 chr7:148820504 ZNF425 -0.38 -6.11 -0.31 2.67e-9 Lung function (FEV1/FVC); LIHC cis rs1775715 0.737 rs11817598 chr10:32206259 A/G cg14930904 chr10:32216787 ARHGAP12 0.37 6.55 0.33 2.07e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs6674176 0.561 rs12127226 chr1:44395309 C/T cg12908607 chr1:44402522 ARTN -0.48 -8.18 -0.4 5.56e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4713118 0.629 rs203888 chr6:28021589 C/T cg16479474 chr6:28041457 NA 0.45 7.13 0.36 5.92e-12 Parkinson's disease; LIHC cis rs10276381 1.000 rs10281214 chr7:28185544 G/C cg23620719 chr7:28220237 JAZF1 0.63 7.78 0.39 8.43e-14 Crohn's disease; LIHC cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg23221052 chr5:179740743 GFPT2 -0.42 -5.98 -0.31 5.58e-9 Height; LIHC cis rs4654899 0.758 rs7556221 chr1:21455559 C/G cg08539965 chr1:21396338 EIF4G3 0.32 5.79 0.3 1.59e-8 Superior frontal gyrus grey matter volume; LIHC cis rs600806 0.713 rs10745305 chr1:110012148 A/G cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.72 -0.39 1.25e-13 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.771 rs2563336 chr5:140107199 A/G cg19875535 chr5:140030758 IK -0.4 -6.58 -0.34 1.78e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs739401 0.611 rs450817 chr11:3056712 A/G cg25174290 chr11:3078921 CARS 0.61 9.06 0.44 1.01e-17 Longevity; LIHC cis rs9394841 0.692 rs9381095 chr6:41806708 T/A cg17623882 chr6:41773611 USP49 -0.43 -5.85 -0.3 1.13e-8 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs11628318 0.614 rs7154538 chr14:103068112 A/G cg23461800 chr14:103021989 NA -0.45 -6.43 -0.33 4.36e-10 Platelet count; LIHC cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg02353165 chr6:42928485 GNMT 0.76 11.75 0.54 5.14e-27 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg02969873 chr4:1330999 MAEA -0.41 -6.27 -0.32 1.1e-9 Longevity; LIHC cis rs4319547 0.695 rs55834409 chr12:122862560 C/G cg23029597 chr12:123009494 RSRC2 0.51 7.25 0.37 2.74e-12 Body mass index; LIHC cis rs2050392 0.624 rs303435 chr10:30731491 T/C cg25182066 chr10:30743637 MAP3K8 -0.64 -10.39 -0.49 3.58e-22 Inflammatory bowel disease; LIHC cis rs644799 0.672 rs11021347 chr11:95653494 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.74 11.86 0.54 2e-27 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.74 12.73 0.57 1.17e-30 Prudent dietary pattern; LIHC cis rs155076 0.938 rs261375 chr13:21871882 A/G cg11317459 chr13:21872234 NA 1.19 13.07 0.58 5.94e-32 White matter hyperintensity burden; LIHC cis rs6750047 0.647 rs62136320 chr2:38275953 T/G cg07380506 chr2:38303506 CYP1B1 0.59 7.56 0.38 3.66e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs644799 1.000 rs566204 chr11:95580926 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.73 0.67 2.53e-46 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs55665837 1.000 rs10832264 chr11:14459982 T/A cg19336497 chr11:14380999 RRAS2 -0.44 -7.99 -0.4 2.15e-14 Vitamin D levels; LIHC cis rs5769765 0.773 rs7410304 chr22:50316835 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.7 -8.65 -0.42 1.97e-16 Schizophrenia; LIHC cis rs17125944 0.505 rs118053951 chr14:53259829 G/A cg00686598 chr14:53173677 PSMC6 1.22 15.09 0.63 8.39e-40 Alzheimer's disease (late onset); LIHC cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg00684032 chr4:1343700 KIAA1530 0.36 5.9 0.3 8.67e-9 Obesity-related traits; LIHC cis rs4975709 0.838 rs4975752 chr5:1880588 A/C cg15595755 chr5:1867978 NA 0.34 6.38 0.33 5.66e-10 Cardiovascular disease risk factors; LIHC cis rs34779708 0.931 rs12768019 chr10:35389843 T/C cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1816752 0.870 rs7981337 chr13:25015053 A/C cg02811702 chr13:24901961 NA 0.26 6.6 0.34 1.56e-10 Obesity-related traits; LIHC cis rs1707322 0.717 rs11211161 chr1:46148138 A/C cg06784218 chr1:46089804 CCDC17 0.41 7.51 0.38 5.23e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg25231972 chr10:31608136 ZEB1;LOC220930 -0.43 -6.18 -0.32 1.83e-9 Triglycerides; LIHC trans rs11165623 0.543 rs60982887 chr1:96989155 T/G cg10631902 chr5:14652156 NA -0.29 -6.75 -0.34 6.39e-11 Hip circumference;Waist circumference; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16574807 chr4:6945745 TBC1D14 0.41 6.67 0.34 1.05e-10 Longevity; LIHC cis rs9902453 0.765 rs62068653 chr17:28212663 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 14.0 0.6 1.67e-35 Coffee consumption (cups per day); LIHC trans rs10213084 1.000 rs10213649 chr4:147499554 C/T cg18061433 chr10:21435895 C10orf113;NEBL 0.49 6.12 0.31 2.52e-9 Heart rate; LIHC cis rs7582180 0.629 rs11688285 chr2:100948054 A/C cg14675211 chr2:100938903 LONRF2 0.53 8.41 0.41 1.13e-15 Intelligence (multi-trait analysis); LIHC cis rs1401999 1.000 rs2176824 chr3:183654029 C/G cg05044414 chr3:183734942 ABCC5 0.34 5.91 0.3 8.31e-9 Anterior chamber depth; LIHC cis rs1005277 0.579 rs2749616 chr10:38510993 A/T cg00409905 chr10:38381863 ZNF37A -0.57 -9.57 -0.46 2.16e-19 Extrinsic epigenetic age acceleration; LIHC trans rs10506458 0.915 rs17738485 chr12:63394932 T/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.75 -10.68 -0.5 3.56e-23 Hemostatic factors and hematological phenotypes; LIHC trans rs1814175 0.765 rs1721990 chr11:49912154 G/C cg03929089 chr4:120376271 NA -0.89 -17.68 -0.69 3.81e-50 Height; LIHC cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg04025307 chr7:1156635 C7orf50 0.57 9.31 0.45 1.64e-18 Longevity;Endometriosis; LIHC cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg10360323 chr17:41437877 NA 0.41 6.16 0.32 2.04e-9 Menopause (age at onset); LIHC cis rs2932538 0.922 rs6690169 chr1:113114974 A/G cg22162597 chr1:113214053 CAPZA1 0.73 11.03 0.51 2.09e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC trans rs2727020 0.590 rs7949936 chr11:49378902 G/A cg15704280 chr7:45808275 SEPT13 -0.75 -10.82 -0.5 1.16e-23 Coronary artery disease; LIHC cis rs1198430 0.925 rs1767148 chr1:23765472 A/G cg19827787 chr1:23763612 ASAP3 0.35 6.22 0.32 1.48e-9 Total cholesterol levels; LIHC cis rs9430161 0.579 rs11121667 chr1:11038476 C/T cg27631724 chr1:11040367 C1orf127 0.41 8.7 0.43 1.37e-16 Ewing sarcoma; LIHC cis rs798554 0.797 rs1182184 chr7:2872446 G/A cg19717773 chr7:2847554 GNA12 -0.43 -6.64 -0.34 1.26e-10 Height; LIHC cis rs7586673 0.930 rs6432667 chr2:161905001 T/C cg22496339 chr2:162101262 NA 0.65 9.69 0.46 9.14e-20 Intelligence (multi-trait analysis); LIHC cis rs611744 0.967 rs603571 chr8:109213893 A/C cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs1008375 1.000 rs2058339 chr4:17678456 C/T cg16339924 chr4:17578868 LAP3 0.4 5.81 0.3 1.41e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs780094 0.544 rs2303370 chr2:27651375 C/T cg05484376 chr2:27715224 FNDC4 0.34 5.76 0.3 1.87e-8 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs7927771 0.832 rs896816 chr11:47394338 T/C cg20307385 chr11:47447363 PSMC3 0.44 5.78 0.3 1.68e-8 Subjective well-being; LIHC cis rs1003719 0.762 rs34273703 chr21:38475019 A/G cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC trans rs61931739 0.534 rs11052974 chr12:34029877 T/G cg26384229 chr12:38710491 ALG10B 0.52 7.17 0.36 4.69e-12 Morning vs. evening chronotype; LIHC cis rs2204008 0.837 rs11180549 chr12:38236950 A/G cg26384229 chr12:38710491 ALG10B 0.87 10.81 0.5 1.21e-23 Bladder cancer; LIHC cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg26831259 chr4:1366826 KIAA1530 -0.35 -5.75 -0.3 1.94e-8 Obesity-related traits; LIHC cis rs9549367 0.713 rs3024745 chr13:113821598 A/G cg18105134 chr13:113819100 PROZ -0.73 -11.79 -0.54 3.76e-27 Platelet distribution width; LIHC cis rs12711979 0.692 rs6751947 chr2:3820739 G/A cg17052675 chr2:3827356 NA -0.42 -7.19 -0.36 4.16e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg26338869 chr17:61819248 STRADA 0.52 6.97 0.35 1.61e-11 Height; LIHC cis rs798502 0.541 rs2644307 chr7:2832973 G/A cg19717773 chr7:2847554 GNA12 -0.4 -7.55 -0.38 3.89e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Inflammatory bowel disease;Waist circumference adjusted for BMI in non-smokers;Ulcerative colitis;Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); LIHC cis rs72634258 0.699 rs2493214 chr1:7994420 A/G cg25007680 chr1:8021821 PARK7 0.46 6.29 0.32 9.96e-10 Inflammatory bowel disease; LIHC trans rs6934970 1.000 rs62413976 chr6:113060338 C/T cg09308777 chr6:169852575 NA 0.58 6.06 0.31 3.61e-9 Bipolar disorder (body mass index interaction); LIHC cis rs7927592 0.763 rs624003 chr11:68231240 C/T cg20283391 chr11:68216788 NA -0.38 -6.02 -0.31 4.43e-9 Total body bone mineral density; LIHC cis rs36051895 0.560 rs10975009 chr9:5220397 T/G cg02405213 chr9:5042618 JAK2 -0.63 -9.95 -0.47 1.14e-20 Pediatric autoimmune diseases; LIHC cis rs8180040 0.966 rs2291298 chr3:47555142 C/A cg16586182 chr3:47516702 SCAP -0.43 -7.46 -0.37 7.39e-13 Colorectal cancer; LIHC cis rs61863818 0.709 rs10786343 chr10:99159465 C/A cg20016023 chr10:99160130 RRP12 -0.42 -6.69 -0.34 8.89e-11 Monocyte percentage of white cells; LIHC cis rs67478160 0.595 rs8022783 chr14:104245573 T/C cg01849466 chr14:104193079 ZFYVE21 -0.48 -7.67 -0.38 1.79e-13 Schizophrenia; LIHC cis rs897984 0.683 rs13337900 chr16:30822409 G/A cg00531865 chr16:30841666 NA -0.41 -6.58 -0.34 1.76e-10 Dementia with Lewy bodies; LIHC cis rs2839186 0.903 rs61182475 chr21:47707050 T/A cg11766577 chr21:47581405 C21orf56 -0.37 -5.75 -0.3 1.99e-8 Testicular germ cell tumor; LIHC cis rs9457247 0.646 rs239934 chr6:167412048 G/A cg23791538 chr6:167370224 RNASET2 -0.54 -8.45 -0.42 8.47e-16 Crohn's disease; LIHC cis rs4147929 0.532 rs4147930 chr19:1064193 G/A cg05372495 chr19:1063624 ABCA7 -0.41 -6.61 -0.34 1.47e-10 Alzheimer's disease (late onset); LIHC cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg03517284 chr6:25882590 NA -0.63 -8.87 -0.43 3.99e-17 Blood metabolite levels; LIHC cis rs9457247 1.000 rs430477 chr6:167389851 T/C cg12798992 chr6:167411361 FGFR1OP 0.59 9.67 0.46 1.04e-19 Crohn's disease; LIHC cis rs2708977 0.932 rs12329128 chr2:97284917 G/A cg01950434 chr2:97203154 ARID5A 0.51 6.54 0.33 2.28e-10 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg11301795 chr4:187892539 NA -0.27 -7.22 -0.36 3.45e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs7520050 0.778 rs2934857 chr1:46039612 A/G cg03146154 chr1:46216737 IPP 0.47 7.47 0.37 6.97e-13 Red blood cell count;Reticulocyte count; LIHC cis rs80282103 0.867 rs7098169 chr10:1078601 G/A cg20335179 chr10:1068567 C10orf110;IDI2 -0.61 -6.75 -0.34 6.5e-11 Glomerular filtration rate (creatinine); LIHC cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg06481639 chr22:41940642 POLR3H 0.72 7.24 0.36 2.91e-12 Vitiligo; LIHC cis rs11677370 0.603 rs10198219 chr2:3854600 T/C cg17052675 chr2:3827356 NA -0.51 -6.42 -0.33 4.56e-10 Type 2 diabetes; LIHC cis rs2243480 0.803 rs13224048 chr7:65993766 G/A cg05590025 chr7:65112418 INTS4L2 -0.53 -5.77 -0.3 1.82e-8 Diabetic kidney disease; LIHC cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.87 0.3 1.05e-8 Menopause (age at onset); LIHC cis rs11148252 0.532 rs9536262 chr13:53303074 A/C cg12458913 chr13:53173898 NA -0.54 -8.22 -0.41 4.3e-15 Lewy body disease; LIHC cis rs6754311 0.731 rs745500 chr2:136583192 G/A cg17750252 chr2:136567154 LCT 0.34 6.21 0.32 1.52e-9 Mosquito bite size; LIHC cis rs1005277 0.557 rs1854563 chr10:38434961 G/A cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1904096 0.506 rs7697827 chr4:95184748 G/A cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.36 -0.45 1.11e-18 Type 2 diabetes; LIHC cis rs80282103 0.867 rs11819178 chr10:1098417 A/G cg18964960 chr10:1102726 WDR37 0.75 6.93 0.35 2.09e-11 Glomerular filtration rate (creatinine); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06500355 chr6:111804104 REV3L 0.42 6.8 0.35 4.78e-11 Lung function (FEV1/FVC); LIHC cis rs1892700 0.764 rs71326956 chr21:34900282 C/T cg14850771 chr21:34775459 IFNGR2 -0.45 -5.94 -0.31 7.19e-9 Educational attainment; LIHC cis rs9486719 0.857 rs3798293 chr6:97033370 A/G cg06623918 chr6:96969491 KIAA0776 -0.7 -7.18 -0.36 4.38e-12 Migraine;Coronary artery disease; LIHC cis rs798554 0.679 rs7807978 chr7:2814635 C/T cg13628971 chr7:2884303 GNA12 0.4 6.47 0.33 3.45e-10 Height; LIHC cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg07677032 chr17:61819896 STRADA 0.43 6.12 0.31 2.53e-9 Prudent dietary pattern; LIHC cis rs2758596 1.000 rs2842866 chr1:156159721 G/A cg24450063 chr1:156163899 SLC25A44 0.96 10.36 0.49 4.51e-22 Paclitaxel disposition in epithelial ovarian cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg14237674 chr17:43239170 HEXIM2 0.41 6.45 0.33 3.83e-10 Cognitive function; LIHC cis rs80282103 0.764 rs12268949 chr10:1104257 A/G cg08668510 chr10:1095578 IDI1 0.7 7.0 0.35 1.36e-11 Glomerular filtration rate (creatinine); LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg25029360 chr8:141646502 EIF2C2 -0.46 -6.99 -0.35 1.44e-11 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC cis rs6545883 0.718 rs3771260 chr2:61762384 G/T cg14146966 chr2:61757674 XPO1 0.48 8.45 0.42 8.6e-16 Tuberculosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00029053 chr2:10830014 NOL10 0.48 6.69 0.34 8.94e-11 Lung function (FEV1/FVC); LIHC cis rs12286929 0.609 rs11601751 chr11:115094117 C/T cg04055981 chr11:115044050 NA 0.45 6.47 0.33 3.43e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7647973 0.769 rs11130181 chr3:49109919 G/A cg07636037 chr3:49044803 WDR6 0.76 9.65 0.46 1.18e-19 Menarche (age at onset); LIHC cis rs17685 0.753 rs1104879 chr7:75685568 C/T cg01364799 chr7:75623366 TMEM120A -0.49 -7.53 -0.38 4.58e-13 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9916302 0.904 rs7210488 chr17:37539819 T/G cg07936489 chr17:37558343 FBXL20 0.85 13.75 0.6 1.49e-34 Glomerular filtration rate (creatinine); LIHC cis rs28830936 0.966 rs28432037 chr15:42126779 G/A cg17847044 chr15:42102381 MAPKBP1 -0.29 -5.79 -0.3 1.58e-8 Diastolic blood pressure; LIHC cis rs6121246 0.909 rs6060812 chr20:30292803 C/T cg13852791 chr20:30311386 BCL2L1 0.97 9.82 0.47 3.37e-20 Mean corpuscular hemoglobin; LIHC cis rs9296092 0.538 rs9469487 chr6:33516943 G/T cg13560919 chr6:33536144 NA -0.38 -6.36 -0.33 6.3e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18447950 chr17:79073781 BAIAP2 0.42 6.59 0.34 1.68e-10 Longevity; LIHC cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg03354898 chr7:1950403 MAD1L1 0.37 5.84 0.3 1.25e-8 Bipolar disorder and schizophrenia; LIHC cis rs9733 0.519 rs11204717 chr1:150709129 T/A cg17724175 chr1:150552817 MCL1 0.49 9.82 0.47 3.15e-20 Tonsillectomy; LIHC cis rs6951245 0.744 rs10265758 chr7:1172518 C/T cg03188948 chr7:1209495 NA 0.78 6.37 0.33 6.1e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9309473 0.950 rs6711001 chr2:73850820 C/G cg20560298 chr2:73613845 ALMS1 -0.53 -6.65 -0.34 1.13e-10 Metabolite levels; LIHC cis rs7246657 0.943 rs10424574 chr19:37838393 A/G cg23950597 chr19:37808831 NA -0.54 -7.02 -0.35 1.23e-11 Coronary artery calcification; LIHC cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg19500098 chr13:21900506 NA 0.38 6.01 0.31 4.78e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7089973 0.668 rs10885622 chr10:116643844 C/T cg23260525 chr10:116636907 FAM160B1 0.38 7.26 0.37 2.68e-12 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs916888 0.773 rs199448 chr17:44809001 A/G cg22968622 chr17:43663579 NA 1.19 13.36 0.59 4.94e-33 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4843747 0.641 rs11117353 chr16:88090895 A/G cg00677901 chr16:88017247 BANP 0.55 8.49 0.42 6.17e-16 Menopause (age at onset); LIHC cis rs9640161 0.789 rs4554381 chr7:150025567 G/A cg21361702 chr7:150065534 REPIN1 0.46 6.3 0.32 9.39e-10 Blood protein levels;Circulating chemerin levels; LIHC cis rs9916302 0.904 rs801419 chr17:37466327 A/G cg00129232 chr17:37814104 STARD3 0.39 6.25 0.32 1.19e-9 Glomerular filtration rate (creatinine); LIHC cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg00149659 chr3:10157352 C3orf10 0.62 6.52 0.33 2.55e-10 Alzheimer's disease; LIHC cis rs2370759 1.000 rs79487858 chr10:32616405 T/C cg18270830 chr10:32634957 EPC1 0.53 6.52 0.33 2.49e-10 Sexual dysfunction (female); LIHC cis rs67460515 0.596 rs35127376 chr3:160927289 T/C cg17135325 chr3:160939158 NMD3 0.59 8.47 0.42 7.36e-16 Parkinson's disease; LIHC cis rs6952808 0.771 rs10269191 chr7:1915731 A/G cg04267008 chr7:1944627 MAD1L1 -0.58 -8.7 -0.43 1.39e-16 Bipolar disorder and schizophrenia; LIHC cis rs778371 0.647 rs4144797 chr2:233562197 T/C cg08000102 chr2:233561755 GIGYF2 0.76 9.1 0.44 7.57e-18 Schizophrenia; LIHC cis rs7107174 1.000 rs10899470 chr11:78020052 C/T cg02023728 chr11:77925099 USP35 0.53 9.99 0.48 8.91e-21 Testicular germ cell tumor; LIHC cis rs2153535 0.580 rs1855769 chr6:8473095 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.03 0.4 1.56e-14 Motion sickness; LIHC cis rs17826219 0.500 rs57005940 chr17:29066329 C/G cg14067834 chr17:29058358 SUZ12P 0.7 6.99 0.35 1.41e-11 Body mass index; LIHC cis rs4631830 0.683 rs10763193 chr10:51504938 G/A cg20129853 chr10:51489980 NA 0.4 8.66 0.42 1.88e-16 Prostate-specific antigen levels; LIHC cis rs9297145 0.565 rs12705030 chr7:98765041 A/G cg05967295 chr7:98741636 SMURF1 -0.39 -6.42 -0.33 4.67e-10 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs11711311 0.955 rs9860642 chr3:113419211 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.45 8.24 0.41 3.66e-15 IgG glycosylation; LIHC cis rs2404602 0.716 rs12902174 chr15:76863540 T/C cg03037974 chr15:76606532 NA 0.74 14.47 0.62 2.32e-37 Blood metabolite levels; LIHC cis rs2280018 0.581 rs7404524 chr16:15129158 A/G cg27102117 chr16:15229624 NA 0.29 6.24 0.32 1.28e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs55882075 0.690 rs12374485 chr5:179131395 G/C cg14593053 chr5:179126677 CANX 0.43 7.84 0.39 5.79e-14 Monocyte percentage of white cells; LIHC cis rs11077998 0.967 rs7502945 chr17:80495039 T/C cg10255544 chr17:80519551 FOXK2 0.48 8.76 0.43 8.98e-17 Reticulocyte fraction of red cells; LIHC cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg06481639 chr22:41940642 POLR3H -0.69 -6.99 -0.35 1.47e-11 Vitiligo; LIHC cis rs922107 0.738 rs12723903 chr1:90037050 C/T cg15422784 chr1:90023713 LRRC8B -0.47 -7.53 -0.38 4.66e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs769267 0.899 rs67720221 chr19:19440864 C/T cg03709012 chr19:19516395 GATAD2A -0.91 -15.29 -0.64 1.36e-40 Tonsillectomy; LIHC cis rs2066819 1.000 rs76430365 chr12:56699993 A/C cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs4888262 0.526 rs8056718 chr16:74612030 G/C cg01733217 chr16:74700730 RFWD3 0.81 16.08 0.66 1.02e-43 Testicular germ cell tumor; LIHC cis rs116095464 0.558 rs62347678 chr5:227496 A/G cg22496380 chr5:211416 CCDC127 -1.0 -10.34 -0.49 5.36e-22 Breast cancer; LIHC cis rs1008375 1.000 rs11737138 chr4:17657986 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.83 0.3 1.29e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4555082 0.874 rs4677 chr14:105717279 T/C cg06808227 chr14:105710500 BRF1 -0.63 -8.63 -0.42 2.35e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs17095355 1.000 rs12247564 chr10:111721400 G/A cg00817464 chr10:111662876 XPNPEP1 -0.4 -5.84 -0.3 1.21e-8 Biliary atresia; LIHC trans rs6489882 0.867 rs1859332 chr12:113371114 T/C cg10175203 chr3:128143634 NA 0.38 6.19 0.32 1.7e-9 Chronic lymphocytic leukemia; LIHC cis rs2637266 1.000 rs12262400 chr10:78386862 T/C cg18941641 chr10:78392320 NA 0.3 6.52 0.33 2.5e-10 Pulmonary function; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg26642844 chr7:2419167 EIF3B -0.38 -6.37 -0.33 6.23e-10 Calcium levels; LIHC cis rs10848704 0.956 rs10848703 chr12:2882250 C/T cg19995117 chr12:2880862 NA 0.38 6.9 0.35 2.59e-11 Quantitative traits; LIHC cis rs1443512 0.812 rs4759058 chr12:54339052 C/A cg17410650 chr12:54324560 NA -0.37 -6.69 -0.34 9.37e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); LIHC cis rs1823913 1.000 rs4853462 chr2:192123804 C/A cg12404831 chr2:192114017 MYO1B -0.32 -6.54 -0.33 2.21e-10 Obesity-related traits; LIHC cis rs10504229 1.000 rs76270388 chr8:58195605 T/A cg02290350 chr8:58132656 NA 0.47 9.18 0.44 4.31e-18 Developmental language disorder (linguistic errors); LIHC cis rs7264396 0.635 rs6058365 chr20:34508092 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.65 -10.59 -0.5 7.71e-23 Total cholesterol levels; LIHC cis rs10492096 1.000 rs11064218 chr12:6586261 C/T cg13857086 chr12:6580257 VAMP1 0.66 6.59 0.34 1.63e-10 Hip geometry; LIHC cis rs11190604 1.000 rs9420782 chr10:102235015 G/A cg07080220 chr10:102295463 HIF1AN 0.5 7.18 0.36 4.38e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg21724239 chr8:58056113 NA 0.58 7.68 0.38 1.72e-13 Developmental language disorder (linguistic errors); LIHC cis rs12477438 0.520 rs12621007 chr2:99791946 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 15.2 0.64 3.05e-40 Chronic sinus infection; LIHC cis rs1816752 0.789 rs7986037 chr13:25012853 A/G cg02811702 chr13:24901961 NA 0.26 6.61 0.34 1.5e-10 Obesity-related traits; LIHC cis rs8044995 0.563 rs55968019 chr16:68398111 G/A cg03983715 chr16:68378420 PRMT7 -0.48 -5.84 -0.3 1.24e-8 Schizophrenia; LIHC cis rs941408 0.928 rs2741991 chr19:2802092 T/C cg06609049 chr19:2785107 THOP1 0.61 9.5 0.46 3.92e-19 Total cholesterol levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01534608 chr4:187646364 FAT1 0.44 6.76 0.34 5.8e-11 Cognitive function; LIHC cis rs1165668 0.785 rs2583223 chr12:104316841 G/A cg21863207 chr12:104234989 NT5DC3 0.46 8.01 0.4 1.77e-14 Coronary heart disease (SNP X SNP interaction); LIHC cis rs17270561 0.887 rs12201170 chr6:25866247 A/G cg17691542 chr6:26056736 HIST1H1C 0.79 8.76 0.43 9.38e-17 Iron status biomarkers; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg01259702 chr19:662807 RNF126 -0.47 -6.04 -0.31 3.93e-9 Electroencephalogram traits; LIHC cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg05368731 chr17:41323189 NBR1 0.72 12.37 0.56 2.77e-29 Menopause (age at onset); LIHC cis rs916888 0.821 rs199514 chr17:44856881 G/A cg01570182 chr17:44337453 NA -0.98 -9.89 -0.47 1.96e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs35272691 1 rs35272691 chr17:38157841 T/C cg17467752 chr17:38218738 THRA -0.51 -8.78 -0.43 7.7e-17 White blood cell count (neutrophil); LIHC trans rs11098499 0.754 rs1980025 chr4:120252806 A/G cg25214090 chr10:38739885 LOC399744 -0.51 -8.41 -0.41 1.13e-15 Corneal astigmatism; LIHC cis rs1799949 0.602 rs8176257 chr17:41216205 G/T cg23758822 chr17:41437982 NA 0.84 13.9 0.6 4e-35 Menopause (age at onset); LIHC cis rs208515 0.525 rs12214310 chr6:66666308 A/G cg07460842 chr6:66804631 NA 0.78 8.89 0.43 3.7e-17 Exhaled nitric oxide levels; LIHC cis rs7044106 0.762 rs1158553 chr9:123400974 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 11.35 0.52 1.55e-25 Hip circumference adjusted for BMI; LIHC cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg17971929 chr21:40555470 PSMG1 -0.43 -6.48 -0.33 3.16e-10 Cognitive function; LIHC cis rs11098499 0.789 rs10212719 chr4:120254437 T/C cg09307838 chr4:120376055 NA 0.7 11.03 0.51 2.13e-24 Corneal astigmatism; LIHC cis rs7926971 0.655 rs7927422 chr11:12660894 T/C cg25843174 chr11:12811716 TEAD1 0.26 5.99 0.31 5.38e-9 Height; LIHC cis rs4665809 0.941 rs2289021 chr2:26362515 A/C cg27170947 chr2:26402098 FAM59B 0.63 7.93 0.39 3.17e-14 Gut microbiome composition (summer); LIHC cis rs9733 0.519 rs1336899 chr1:150678910 T/C cg13175981 chr1:150552382 MCL1 -0.42 -5.74 -0.3 2.12e-8 Tonsillectomy; LIHC cis rs9914988 0.887 rs34644886 chr17:27168327 T/C cg20469991 chr17:27169893 C17orf63 -0.61 -7.12 -0.36 6.24e-12 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg26338869 chr17:61819248 STRADA 0.61 8.83 0.43 5.47e-17 Prudent dietary pattern; LIHC cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.25e-9 Menopause (age at onset); LIHC cis rs10089 1.000 rs4835945 chr5:127526481 C/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.51 6.43 0.33 4.25e-10 Ileal carcinoids; LIHC cis rs9733 0.596 rs12072339 chr1:150686099 A/G cg17724175 chr1:150552817 MCL1 0.48 9.67 0.46 1.02e-19 Tonsillectomy; LIHC cis rs17826219 0.636 rs4055314 chr17:29079769 T/C cg14067834 chr17:29058358 SUZ12P 0.68 6.63 0.34 1.32e-10 Body mass index; LIHC cis rs1401999 0.714 rs1533683 chr3:183635488 C/T cg01324343 chr3:183735012 ABCC5 0.56 8.89 0.43 3.58e-17 Anterior chamber depth; LIHC cis rs10464366 0.746 rs6945402 chr7:39145385 A/T cg21665744 chr7:39171113 POU6F2 0.33 6.03 0.31 4.33e-9 IgG glycosylation; LIHC cis rs11690935 1.000 rs35549875 chr2:172532392 A/G cg13550731 chr2:172543902 DYNC1I2 0.92 17.6 0.69 8.11e-50 Schizophrenia; LIHC cis rs7208859 0.623 rs7219712 chr17:29080570 G/T cg13385521 chr17:29058706 SUZ12P 0.8 7.84 0.39 5.76e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2153535 0.580 rs1360054 chr6:8520377 C/A cg23788917 chr6:8435910 SLC35B3 0.62 8.82 0.43 5.8e-17 Motion sickness; LIHC cis rs11718455 0.921 rs35872933 chr3:44028515 T/G cg08738300 chr3:44038990 NA 0.52 9.11 0.44 7.22e-18 Coronary artery disease; LIHC cis rs1557765 0.527 rs11024272 chr11:17395760 T/C cg15432903 chr11:17409602 KCNJ11 0.43 6.57 0.33 1.93e-10 Body mass index;Social communication problems; LIHC cis rs6545883 0.859 rs13004855 chr2:61505072 C/T cg14146966 chr2:61757674 XPO1 -0.44 -7.35 -0.37 1.44e-12 Tuberculosis; LIHC cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg27572855 chr1:25598939 RHD 0.39 8.4 0.41 1.17e-15 Plateletcrit;Mean corpuscular volume; LIHC cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg24531977 chr5:56204891 C5orf35 -0.67 -9.63 -0.46 1.44e-19 Initial pursuit acceleration; LIHC cis rs929354 0.772 rs6954050 chr7:156978554 A/G cg17757837 chr7:157058334 UBE3C 0.74 12.02 0.54 5.32e-28 Body mass index; LIHC cis rs7618501 0.521 rs11130222 chr3:49901060 A/T cg24110177 chr3:50126178 RBM5 -0.55 -8.49 -0.42 6.38e-16 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg12016809 chr21:47604291 C21orf56 0.44 6.64 0.34 1.24e-10 Testicular germ cell tumor; LIHC cis rs7937682 0.883 rs484834 chr11:111465761 G/C cg09085632 chr11:111637200 PPP2R1B -0.92 -11.24 -0.52 3.7e-25 Primary sclerosing cholangitis; LIHC cis rs3106136 0.546 rs183993 chr4:95130025 G/A cg11021082 chr4:95130006 SMARCAD1 -0.51 -9.47 -0.46 4.84e-19 Capecitabine sensitivity; LIHC cis rs1707322 1.000 rs785493 chr1:46584859 A/G cg06784218 chr1:46089804 CCDC17 -0.4 -7.22 -0.36 3.38e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs763121 0.853 rs926299 chr22:39095698 C/G cg21395723 chr22:39101663 GTPBP1 0.4 6.67 0.34 1.04e-10 Menopause (age at onset); LIHC cis rs8005677 1.000 rs4982712 chr14:23403728 A/G cg25600027 chr14:23388339 RBM23 -0.4 -5.75 -0.3 1.97e-8 Cognitive ability (multi-trait analysis); LIHC cis rs1559088 0.948 rs10408093 chr19:33597816 T/C cg17764715 chr19:33622953 WDR88 0.45 6.51 0.33 2.64e-10 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7100689 0.646 rs7077854 chr10:82124070 C/T cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.83 -12.47 -0.56 1.12e-29 Alzheimer's disease; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg10990685 chr12:120720139 NME2P1 0.52 6.37 0.33 5.93e-10 Lung function (FEV1); LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg02993280 chr1:107599747 PRMT6 0.66 10.66 0.5 4.28e-23 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs9394159 0.583 rs4713650 chr6:33616828 C/T cg14003231 chr6:33640908 ITPR3 -0.26 -5.84 -0.3 1.21e-8 Graves' disease; LIHC cis rs9818758 0.505 rs67286839 chr3:49265744 C/T cg00383909 chr3:49044727 WDR6 0.79 6.68 0.34 9.53e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.8 -14.72 -0.62 2.53e-38 Prudent dietary pattern; LIHC cis rs9916302 0.851 rs11078904 chr17:37650569 G/A cg15445000 chr17:37608096 MED1 0.38 5.78 0.3 1.68e-8 Glomerular filtration rate (creatinine); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg23262918 chr12:76953136 OSBPL8 -0.43 -6.4 -0.33 5.22e-10 Calcium levels; LIHC cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg11941060 chr3:133502564 NA -0.4 -5.83 -0.3 1.32e-8 Iron status biomarkers; LIHC cis rs754466 1.000 rs56256440 chr10:79698207 A/G cg17075019 chr10:79541650 NA -0.56 -7.37 -0.37 1.32e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg10802521 chr3:52805072 NEK4 -0.37 -5.9 -0.3 8.82e-9 Bipolar disorder; LIHC cis rs986417 1.000 rs1313249 chr14:60881997 C/G cg27398547 chr14:60952738 C14orf39 -0.71 -8.26 -0.41 3.13e-15 Gut microbiota (bacterial taxa); LIHC cis rs1008375 0.966 rs2302393 chr4:17654341 G/A cg16339924 chr4:17578868 LAP3 0.45 6.21 0.32 1.5e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs76419734 0.510 rs2553446 chr4:106696476 G/A cg24545054 chr4:106630052 GSTCD;INTS12 -0.67 -7.18 -0.36 4.29e-12 Post bronchodilator FEV1; LIHC cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg10360323 chr17:41437877 NA 0.41 6.09 0.31 3.1e-9 Menopause (age at onset); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg11015505 chr11:64645556 EHD1 0.44 6.1 0.31 2.86e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg27170947 chr2:26402098 FAM59B -0.66 -8.34 -0.41 1.9e-15 Gut microbiome composition (summer); LIHC cis rs6500602 0.610 rs1659499 chr16:4595269 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.41 -6.17 -0.32 1.93e-9 Schizophrenia; LIHC cis rs870825 0.860 rs2705899 chr4:185596219 A/G cg04058563 chr4:185651563 MLF1IP 0.65 6.08 0.31 3.29e-9 Blood protein levels; LIHC cis rs11792861 0.888 rs72607168 chr9:111832192 G/C cg05043794 chr9:111880884 C9orf5 -0.29 -6.7 -0.34 8.54e-11 Menarche (age at onset); LIHC trans rs11098499 0.954 rs4577559 chr4:120404043 T/G cg25214090 chr10:38739885 LOC399744 0.58 9.5 0.46 3.69e-19 Corneal astigmatism; LIHC cis rs10847980 0.590 rs1696326 chr12:123311981 A/G cg18912006 chr12:123335444 HIP1R -0.69 -7.05 -0.36 1.01e-11 Adiponectin levels; LIHC trans rs9641123 0.639 rs2677077 chr7:93259217 T/C cg09745688 chr16:2908918 PRSS22 -0.37 -6.47 -0.33 3.33e-10 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction);Lean body mass; LIHC cis rs9611565 0.729 rs203319 chr22:41914593 C/T cg03806693 chr22:41940476 POLR3H -0.51 -6.83 -0.35 3.79e-11 Vitiligo; LIHC cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg06481639 chr22:41940642 POLR3H -0.74 -7.48 -0.37 6.46e-13 Vitiligo; LIHC trans rs7618501 1.000 rs7372725 chr3:49790544 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -14.81 -0.63 1.14e-38 Intelligence (multi-trait analysis); LIHC cis rs7529073 0.740 rs340883 chr1:214145706 A/G cg24083324 chr1:214162604 PROX1 -0.47 -7.08 -0.36 8.17e-12 Schizophrenia; LIHC cis rs10911363 0.592 rs2275675 chr1:183439483 C/T cg09173681 chr1:183549694 NCF2 -0.54 -9.49 -0.46 4.11e-19 Systemic lupus erythematosus; LIHC trans rs1552244 0.572 rs113406084 chr3:10170190 T/C cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs7615952 0.512 rs4646765 chr3:125820707 G/A cg05084668 chr3:125655381 ALG1L -0.4 -6.04 -0.31 4.12e-9 Blood pressure (smoking interaction); LIHC cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg05890377 chr2:74357713 NA 0.63 13.01 0.58 1.06e-31 Gestational age at birth (maternal effect); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07377341 chr1:160068584 IGSF8 0.46 6.41 0.33 4.82e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs3790645 1.000 rs657227 chr1:26892104 T/A cg17456097 chr1:26900765 RPS6KA1 0.4 5.82 0.3 1.33e-8 Glucose homeostasis traits; LIHC cis rs45430 1.000 rs45430 chr21:42746081 C/T cg06102954 chr21:42741788 MX2 0.38 6.48 0.33 3.18e-10 Melanoma; LIHC cis rs7659604 0.676 rs7691955 chr4:122700462 A/T cg19748678 chr4:122722346 EXOSC9 0.65 10.68 0.5 3.54e-23 Type 2 diabetes; LIHC cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.72 -5.73 -0.3 2.25e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg06481639 chr22:41940642 POLR3H 0.61 6.17 0.32 1.9e-9 Vitiligo; LIHC cis rs801193 1.000 rs2707856 chr7:66211010 A/T cg11764359 chr7:65958608 NA 0.71 10.47 0.49 2e-22 Aortic root size; LIHC cis rs9902453 0.845 rs2628165 chr17:28121166 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.66 0.53 1.08e-26 Coffee consumption (cups per day); LIHC cis rs7607369 0.718 rs6727147 chr2:219639024 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs2282802 0.685 rs6889283 chr5:139653439 G/T cg26211634 chr5:139558579 C5orf32 0.39 5.97 0.31 5.83e-9 Intelligence (multi-trait analysis); LIHC cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg23283495 chr1:209979779 IRF6 0.43 6.86 0.35 3.28e-11 Cleft lip with or without cleft palate; LIHC cis rs72627509 0.767 rs6853156 chr4:57774843 C/T cg26694713 chr4:57773883 REST 0.73 10.52 0.49 1.34e-22 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC trans rs2243480 1.000 rs1267820 chr7:66050295 C/G cg10756647 chr7:56101905 PSPH 1.02 12.11 0.55 2.53e-28 Diabetic kidney disease; LIHC cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg18230493 chr5:56204884 C5orf35 0.46 6.19 0.32 1.72e-9 Initial pursuit acceleration; LIHC cis rs600806 0.627 rs2359652 chr1:110008720 T/A cg16275483 chr1:110013120 SYPL2 -0.49 -6.15 -0.32 2.16e-9 Intelligence (multi-trait analysis); LIHC cis rs2070488 0.699 rs13078966 chr3:38517914 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.53 0.56 6.83e-30 Electrocardiographic conduction measures; LIHC cis rs208520 0.690 rs1304672 chr6:66847973 A/G cg07460842 chr6:66804631 NA 0.71 7.65 0.38 2.04e-13 Exhaled nitric oxide output; LIHC cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.93 16.17 0.66 4.25e-44 Platelet count; LIHC cis rs473651 0.935 rs474478 chr2:239335473 C/T cg18131467 chr2:239335373 ASB1 1.05 19.8 0.73 1.11e-58 Multiple system atrophy; LIHC cis rs2708977 1.000 rs13029764 chr2:97328874 C/T cg01950434 chr2:97203154 ARID5A -0.51 -7.62 -0.38 2.52e-13 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs8062405 1.000 rs62036624 chr16:28839930 G/T cg00204512 chr16:28754710 NA 0.34 6.39 0.33 5.51e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs11785400 0.793 rs3735993 chr8:143741170 G/A cg24634471 chr8:143751801 JRK 0.48 7.69 0.38 1.61e-13 Schizophrenia; LIHC cis rs116248771 0.739 rs12633674 chr3:158368217 G/T cg16708174 chr3:158430962 RARRES1 0.48 6.38 0.33 5.61e-10 diarrhoeal disease at age 2; LIHC cis rs116095464 0.558 rs73029475 chr5:206969 T/C cg22857025 chr5:266934 NA -1.65 -16.58 -0.67 9.67e-46 Breast cancer; LIHC cis rs858239 0.601 rs1558313 chr7:23156079 G/A cg23682824 chr7:23144976 KLHL7 0.43 6.46 0.33 3.7e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs559928 0.569 rs7103915 chr11:63944370 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.77 -7.29 -0.37 2.2e-12 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; LIHC cis rs7503807 1.000 rs4890056 chr17:78591211 C/T cg09596252 chr17:78655493 RPTOR -0.39 -6.97 -0.35 1.65e-11 Obesity; LIHC cis rs1577917 0.771 rs3812133 chr6:86354411 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.39 -6.11 -0.31 2.69e-9 Response to antipsychotic treatment; LIHC cis rs2439831 0.681 rs825739 chr15:43592428 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.74 10.96 0.51 3.72e-24 Lung cancer in ever smokers; LIHC cis rs6831352 0.918 rs7694646 chr4:100059732 T/A cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs225245 0.817 rs225302 chr17:33922396 C/T cg05299278 chr17:33885742 SLFN14 0.22 5.77 0.3 1.76e-8 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs7296418 0.630 rs28419092 chr12:123812629 G/C cg00376283 chr12:123451042 ABCB9 0.62 10.27 0.49 9.42e-22 Platelet count; LIHC cis rs4319547 0.695 rs1803290 chr12:122865029 T/C cg05707623 chr12:122985044 ZCCHC8 0.54 7.15 0.36 5.15e-12 Body mass index; LIHC cis rs7937682 0.855 rs539693 chr11:111477387 A/G cg09085632 chr11:111637200 PPP2R1B -0.9 -10.87 -0.51 7.63e-24 Primary sclerosing cholangitis; LIHC cis rs67460515 0.892 rs16832082 chr3:161043571 A/G cg17135325 chr3:160939158 NMD3 0.55 7.94 0.39 2.92e-14 Parkinson's disease; LIHC cis rs9420 1.000 rs9420 chr11:57510294 A/G cg19752551 chr11:57585705 CTNND1 0.5 7.14 0.36 5.46e-12 Schizophrenia; LIHC cis rs35306767 0.903 rs12250936 chr10:870109 C/T cg26597838 chr10:835615 NA 1.14 13.63 0.59 4.31e-34 Eosinophil percentage of granulocytes; LIHC cis rs6840360 0.571 rs7685697 chr4:152558849 A/G cg22705602 chr4:152727874 NA -0.32 -6.31 -0.32 8.74e-10 Intelligence (multi-trait analysis); LIHC trans rs6489882 0.703 rs10850094 chr12:113360563 C/T cg10175203 chr3:128143634 NA -0.39 -6.31 -0.32 8.4e-10 Chronic lymphocytic leukemia; LIHC cis rs8062405 0.755 rs4788073 chr16:28594549 A/G cg07451762 chr16:28383216 NA 0.4 7.3 0.37 1.97e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs77633900 0.772 rs506000 chr15:76817788 T/C cg21673338 chr15:77095150 SCAPER -0.53 -6.09 -0.31 3.11e-9 Non-glioblastoma glioma;Glioma; LIHC cis rs17253792 0.822 rs28754619 chr14:56088394 G/A cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs743757 1.000 rs2236987 chr3:50504546 C/T cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.59 -9.22 -0.45 3.08e-18 Diastolic blood pressure; LIHC cis rs4589502 1.000 rs80263963 chr15:67127228 C/T cg09911534 chr15:67153556 NA -0.5 -6.16 -0.32 2.02e-9 Lung cancer (smoking interaction); LIHC cis rs9381040 0.655 rs6903444 chr6:41014220 C/T cg03644281 chr6:41068752 NFYA;LOC221442 0.4 5.79 0.3 1.63e-8 Alzheimer's disease (late onset); LIHC cis rs12701220 0.655 rs9638973 chr7:1133678 A/G cg18765753 chr7:1198926 ZFAND2A -0.43 -6.18 -0.32 1.81e-9 Bronchopulmonary dysplasia; LIHC cis rs7729447 0.776 rs7738037 chr5:32696549 C/T cg16267343 chr5:32710456 NPR3 0.47 5.84 0.3 1.23e-8 Blood pressure; LIHC cis rs8044995 0.563 rs61746794 chr16:68387457 C/T cg09835421 chr16:68378352 PRMT7 -0.82 -9.6 -0.46 1.71e-19 Schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg22654626 chr19:18699620 C19orf60 0.6 8.12 0.4 8.68e-15 Lung function (FEV1/FVC); LIHC trans rs12752401 0.867 rs12751548 chr1:103067463 A/G cg24921808 chr19:740313 PALM -0.46 -6.1 -0.31 2.94e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs10489202 1.000 rs275157 chr1:168064178 T/C cg24449463 chr1:168025552 DCAF6 -0.5 -6.49 -0.33 3.04e-10 Schizophrenia; LIHC cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg10802521 chr3:52805072 NEK4 -0.44 -7.5 -0.38 5.48e-13 Bipolar disorder; LIHC cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.44 -6.16 -0.32 2.1e-9 Colorectal cancer; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg25195416 chr21:46696626 POFUT2 0.39 6.07 0.31 3.34e-9 Immature fraction of reticulocytes; LIHC cis rs1775715 0.674 rs2778670 chr10:32161676 G/A cg14930904 chr10:32216787 ARHGAP12 0.34 6.01 0.31 4.69e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs1434579 0.966 rs1062098 chr19:44930738 A/G cg15540054 chr19:45004280 ZNF180 0.56 7.61 0.38 2.74e-13 Tuberculosis; LIHC cis rs924607 1.000 rs11746907 chr5:598224 G/A cg04476341 chr5:669733 TPPP -0.4 -9.01 -0.44 1.49e-17 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC trans rs60843830 0.964 rs17713879 chr2:254215 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.63 9.21 0.45 3.43e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC trans rs561341 0.941 rs8081016 chr17:30331751 A/G cg20587970 chr11:113659929 NA -1.41 -12.24 -0.55 7.93e-29 Hip circumference adjusted for BMI; LIHC cis rs17401966 0.838 rs4846209 chr1:10322054 G/A cg15208524 chr1:10270712 KIF1B 0.38 5.82 0.3 1.35e-8 Hepatocellular carcinoma; LIHC cis rs12711979 0.765 rs6705742 chr2:3820672 C/T cg17052675 chr2:3827356 NA -0.42 -7.28 -0.37 2.36e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs4803468 1.000 rs10417311 chr19:41902038 G/A cg14132834 chr19:41945861 ATP5SL -0.43 -6.49 -0.33 3.04e-10 Height; LIHC cis rs17253792 0.822 rs17683728 chr14:56060389 C/T cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs6912958 0.781 rs9444524 chr6:88311260 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.77 -0.39 9.44e-14 Monocyte percentage of white cells; LIHC cis rs7927771 0.965 rs1064608 chr11:47640429 G/C cg18512352 chr11:47633146 NA -0.25 -5.92 -0.31 7.68e-9 Subjective well-being; LIHC cis rs9733 0.519 rs1134067 chr1:150721175 G/T cg18016565 chr1:150552671 MCL1 0.58 11.21 0.52 4.72e-25 Tonsillectomy; LIHC cis rs6840360 0.593 rs6847844 chr4:152693246 C/T cg22705602 chr4:152727874 NA -0.4 -8.5 -0.42 5.82e-16 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg11644478 chr21:40555479 PSMG1 0.85 10.81 0.5 1.31e-23 Cognitive function; LIHC cis rs2153535 0.580 rs7743995 chr6:8496212 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.37 0.41 1.45e-15 Motion sickness; LIHC cis rs12142240 0.667 rs55887761 chr1:46826587 C/A cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg11494091 chr17:61959527 GH2 0.34 5.71 0.3 2.39e-8 Height; LIHC cis rs870825 0.860 rs72689297 chr4:185600957 A/T cg04058563 chr4:185651563 MLF1IP 0.84 7.01 0.35 1.31e-11 Blood protein levels; LIHC cis rs13256369 1.000 rs9329166 chr8:8576655 C/T cg00074818 chr8:8560427 CLDN23 0.39 6.51 0.33 2.67e-10 Obesity-related traits; LIHC cis rs1775715 0.966 rs1755066 chr10:32309160 C/G cg14930904 chr10:32216787 ARHGAP12 -0.41 -7.35 -0.37 1.43e-12 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg07133347 chr1:107600762 PRMT6 -0.45 -6.73 -0.34 6.96e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg02869306 chr7:64672164 INTS4L1 0.28 6.22 0.32 1.42e-9 Calcium levels; LIHC cis rs1144333 0.655 rs58722308 chr1:76423525 A/G cg03433033 chr1:76189801 ACADM 0.53 7.56 0.38 3.79e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs8078723 0.714 rs9915252 chr17:38145088 C/G cg17467752 chr17:38218738 THRA -0.59 -10.13 -0.48 2.93e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9788682 1.000 rs61204066 chr15:78815298 G/A cg06917634 chr15:78832804 PSMA4 -0.5 -7.22 -0.36 3.49e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC trans rs7246657 0.943 rs10407084 chr19:37907792 T/C cg10208301 chr11:6592745 DNHD1 0.46 6.22 0.32 1.41e-9 Coronary artery calcification; LIHC cis rs6502050 0.871 rs7226049 chr17:80071049 A/G cg11859384 chr17:80120422 CCDC57 0.43 5.99 0.31 5.45e-9 Life satisfaction; LIHC cis rs3820068 0.581 rs72645879 chr1:15928199 A/G cg17385448 chr1:15911702 AGMAT 0.34 5.94 0.31 7.13e-9 Systolic blood pressure; LIHC cis rs2439831 0.867 rs2584702 chr15:43684914 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.84 0.51 9.48e-24 Lung cancer in ever smokers; LIHC cis rs986417 1.000 rs1024223 chr14:60926119 C/T cg27398547 chr14:60952738 C14orf39 0.81 9.56 0.46 2.46e-19 Gut microbiota (bacterial taxa); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12713142 chr12:57081325 PTGES3 0.42 6.66 0.34 1.12e-10 Pancreatic cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg24132989 chr6:88050339 C6orf162 0.3 6.27 0.32 1.09e-9 Cognitive function; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg14910368 chr12:57610455 NXPH4 0.57 6.27 0.32 1.11e-9 Lung function (FEV1); LIHC cis rs1728785 1.000 rs7205960 chr16:68565604 G/C cg02972257 chr16:68554789 NA -0.53 -6.19 -0.32 1.73e-9 Ulcerative colitis; LIHC cis rs6762 0.692 rs7928925 chr11:839155 G/A cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.34 -0.45 1.28e-18 Mean platelet volume; LIHC cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg05564831 chr3:52568323 NT5DC2 0.36 5.89 0.3 9.25e-9 Bipolar disorder; LIHC cis rs9929218 0.906 rs34565494 chr16:68741769 C/T cg01231543 chr16:68741748 NA 0.4 5.95 0.31 6.65e-9 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg02891801 chr12:6472782 SCNN1A 0.47 7.67 0.38 1.79e-13 Cognitive function; LIHC cis rs74544699 0.826 rs74499711 chr4:74842764 G/A cg02530824 chr4:74847766 PF4 0.59 7.08 0.36 8.15e-12 Growth-regulated protein alpha levels; LIHC cis rs17345786 0.511 rs12639028 chr3:101346033 G/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.66 10.2 0.48 1.65e-21 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.87 0.57 3.48e-31 Prudent dietary pattern; LIHC cis rs6570726 0.846 rs6919684 chr6:145883801 A/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.86 -0.3 1.12e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.614 rs62084384 chr17:57126842 G/A cg25039879 chr17:56429692 SUPT4H1 0.75 8.46 0.42 7.96e-16 Cognitive test performance; LIHC cis rs7131987 0.903 rs11050153 chr12:29405148 T/C cg21522988 chr12:29376872 FAR2 0.3 6.86 0.35 3.26e-11 QT interval; LIHC cis rs1670533 1.000 rs10084888 chr4:1053814 G/T cg27284194 chr4:1044797 NA 0.6 8.95 0.44 2.33e-17 Recombination rate (females); LIHC cis rs7927592 0.871 rs871212 chr11:68348695 T/A cg20283391 chr11:68216788 NA -0.51 -7.6 -0.38 2.89e-13 Total body bone mineral density; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg00639286 chr5:151138064 ATOX1 0.48 6.64 0.34 1.24e-10 Lung function (FEV1/FVC); LIHC cis rs8016947 0.506 rs7157054 chr14:35785129 G/A cg03549618 chr14:35838977 NA 0.35 5.75 0.3 2.02e-8 Psoriasis; LIHC cis rs6570726 0.935 rs366308 chr6:145814532 T/A cg23711669 chr6:146136114 FBXO30 0.55 9.84 0.47 2.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs11098499 0.909 rs35165976 chr4:120325630 G/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs4141404 0.828 rs2413043 chr22:31648576 G/T cg07713946 chr22:31675144 LIMK2 -0.43 -7.77 -0.39 9.21e-14 Paclitaxel-induced neuropathy; LIHC cis rs1127311 0.905 rs6699729 chr1:154582896 A/T cg17218026 chr1:154582156 ADAR 0.36 7.2 0.36 3.78e-12 C-reactive protein levels or triglyceride levels (pleiotropy); LIHC cis rs4773330 1.000 rs831167 chr13:111795544 C/T cg26911804 chr13:111806221 ARHGEF7 -0.66 -6.65 -0.34 1.18e-10 Bilirubin levels; LIHC cis rs6426558 0.537 rs498020 chr1:227304180 G/A cg10327440 chr1:227177885 CDC42BPA 0.46 7.08 0.36 7.98e-12 Neutrophil percentage of white cells; LIHC cis rs7534824 0.625 rs7545402 chr1:101321076 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 6.77 0.34 5.76e-11 Refractive astigmatism; LIHC cis rs8017423 0.647 rs11623736 chr14:90746471 G/T cg14092571 chr14:90743983 NA 0.45 7.03 0.36 1.13e-11 Mortality in heart failure; LIHC cis rs1865760 0.964 rs9295677 chr6:25933712 T/C cg03517284 chr6:25882590 NA -0.42 -6.35 -0.32 6.8e-10 Height; LIHC cis rs79057730 0.528 rs4719313 chr7:822501 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.76 8.2 0.41 5.07e-15 Initial pursuit acceleration; LIHC cis rs920590 0.758 rs1817836 chr8:19664852 T/C cg17834443 chr8:19674713 INTS10 0.48 7.19 0.36 4.13e-12 Acute lymphoblastic leukemia (childhood); LIHC cis rs7412746 0.611 rs2228099 chr1:150808889 C/G cg18016565 chr1:150552671 MCL1 0.47 9.06 0.44 1.03e-17 Melanoma; LIHC cis rs4803468 1.000 rs11883104 chr19:41923799 T/C cg14132834 chr19:41945861 ATP5SL -0.44 -6.52 -0.33 2.58e-10 Height; LIHC trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg16836995 chr17:43662488 NA -0.75 -7.67 -0.38 1.78e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs2576037 0.796 rs2576039 chr18:44582148 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.48 -7.26 -0.37 2.55e-12 Personality dimensions; LIHC cis rs8114671 0.562 rs6087642 chr20:33468306 T/C cg07148914 chr20:33460835 GGT7 0.64 9.75 0.47 5.44e-20 Height; LIHC cis rs12477438 0.765 rs1054042 chr2:99614396 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.48 -0.49 1.81e-22 Chronic sinus infection; LIHC cis rs7707921 0.881 rs2629744 chr5:81381997 A/T cg15871215 chr5:81402204 ATG10 -0.6 -6.08 -0.31 3.15e-9 Breast cancer; LIHC cis rs365132 0.875 rs4976665 chr5:176352736 C/T cg16309518 chr5:176445507 NA -0.51 -9.46 -0.46 5.1e-19 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs7582180 0.700 rs2309852 chr2:100982527 T/C cg14675211 chr2:100938903 LONRF2 0.53 8.22 0.41 4.14e-15 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.643 rs10794343 chr11:925493 C/T cg10932868 chr11:921992 NA 0.39 7.49 0.38 5.97e-13 Alzheimer's disease (late onset); LIHC cis rs9457247 1.000 rs398278 chr6:167388169 A/G cg07741184 chr6:167504864 NA 0.3 6.92 0.35 2.26e-11 Crohn's disease; LIHC cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg10802521 chr3:52805072 NEK4 -0.44 -7.24 -0.36 2.92e-12 Bipolar disorder; LIHC cis rs34779708 0.931 rs4934731 chr10:35431636 T/C cg03585969 chr10:35415529 CREM 0.79 11.81 0.54 3.14e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6089829 0.926 rs1060491 chr20:61665817 C/A cg03213289 chr20:61660250 NA -0.49 -8.47 -0.42 7.45e-16 Prostate cancer (SNP x SNP interaction); LIHC cis rs4746818 0.818 rs7076011 chr10:70900430 T/C cg11621586 chr10:70884670 VPS26A 0.87 14.26 0.61 1.61e-36 Left atrial antero-posterior diameter; LIHC cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg22800045 chr5:56110881 MAP3K1 0.6 7.37 0.37 1.31e-12 Initial pursuit acceleration; LIHC cis rs12477438 0.734 rs4851184 chr2:99666434 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -15.85 -0.65 8.31e-43 Chronic sinus infection; LIHC cis rs317689 0.690 rs547827 chr12:69669703 G/A cg20891283 chr12:69753455 YEATS4 0.51 7.51 0.38 5.09e-13 Response to diuretic therapy; LIHC cis rs9911578 0.967 rs6503893 chr17:57149695 G/A cg12560992 chr17:57184187 TRIM37 0.97 17.95 0.7 3.2e-51 Intelligence (multi-trait analysis); LIHC cis rs7487075 0.567 rs4768712 chr12:46811521 T/C cg23829395 chr12:46796953 NA 0.36 6.3 0.32 9.14e-10 Itch intensity from mosquito bite; LIHC cis rs4689592 0.619 rs3796908 chr4:7061378 G/A cg02503808 chr4:7069936 GRPEL1 0.77 11.44 0.53 7.3e-26 Monocyte percentage of white cells; LIHC cis rs11864453 0.826 rs6499560 chr16:72147666 G/T cg16558253 chr16:72132732 DHX38 0.5 8.24 0.41 3.84e-15 Fibrinogen levels; LIHC cis rs7918232 0.941 rs10829195 chr10:27431564 G/A cg14240646 chr10:27532245 ACBD5 -0.66 -6.29 -0.32 9.9e-10 Breast cancer; LIHC cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg10862848 chr6:42927986 GNMT -0.27 -6.34 -0.32 7.12e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 14.49 0.62 1.98e-37 Prudent dietary pattern; LIHC cis rs240764 0.578 rs9498252 chr6:101194481 A/G cg12253828 chr6:101329408 ASCC3 0.43 6.79 0.34 5.07e-11 Neuroticism; LIHC trans rs877282 0.755 rs2486578 chr10:785227 C/T cg22713356 chr15:30763199 NA -1.16 -11.12 -0.52 9.83e-25 Uric acid levels; LIHC cis rs8103278 1.000 rs17571725 chr19:46290822 C/T cg11657440 chr19:46296263 DMWD -0.54 -8.52 -0.42 5.21e-16 Coronary artery disease; LIHC cis rs2933343 0.700 rs1680788 chr3:128625318 C/T cg24203234 chr3:128598194 ACAD9 0.45 6.29 0.32 9.77e-10 IgG glycosylation; LIHC cis rs796364 0.806 rs74706215 chr2:200941367 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.65 -7.25 -0.37 2.75e-12 Schizophrenia; LIHC cis rs7075426 0.512 rs9633738 chr10:88183796 T/A cg07322936 chr10:88137208 NA -0.45 -5.85 -0.3 1.17e-8 Migraine without aura; LIHC cis rs7818688 0.654 rs11783262 chr8:95979816 A/G cg16049864 chr8:95962084 TP53INP1 0.61 6.67 0.34 1.04e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg10360323 chr17:41437877 NA 0.41 6.08 0.31 3.13e-9 Menopause (age at onset); LIHC cis rs1577917 0.958 rs12213331 chr6:86504797 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.43 -6.95 -0.35 1.87e-11 Response to antipsychotic treatment; LIHC cis rs3741151 0.892 rs60078907 chr11:73085834 T/C cg17517138 chr11:73019481 ARHGEF17 0.78 6.12 0.31 2.63e-9 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs2952156 0.920 rs2517953 chr17:37841211 G/C cg00129232 chr17:37814104 STARD3 -0.55 -10.43 -0.49 2.7e-22 Asthma; LIHC cis rs72781680 0.800 rs72780112 chr2:23991182 C/T cg08917208 chr2:24149416 ATAD2B 0.84 7.62 0.38 2.45e-13 Lymphocyte counts; LIHC cis rs17539620 0.624 rs62432740 chr6:154836054 C/T cg20019720 chr6:154832845 CNKSR3 0.41 6.21 0.32 1.52e-9 Lipoprotein (a) levels; LIHC cis rs2732480 0.500 rs7297824 chr12:48598650 T/C cg21466736 chr12:48725269 NA -0.7 -10.87 -0.51 7.55e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs12220238 1.000 rs7076721 chr10:75996682 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.25 0.32 1.24e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs10174077 0.687 rs10172023 chr2:152476028 C/G cg19508488 chr2:152266495 RIF1 0.5 6.82 0.35 4.22e-11 Squamous cell lung carcinoma; LIHC trans rs1005277 0.579 rs176886 chr10:38403974 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs909002 0.800 rs3134718 chr1:32089839 C/T cg13919466 chr1:32135498 COL16A1 -0.34 -6.34 -0.32 7.19e-10 Intelligence (multi-trait analysis); LIHC cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg10755058 chr3:40428713 ENTPD3 0.4 6.87 0.35 3.05e-11 Renal cell carcinoma; LIHC cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg11644478 chr21:40555479 PSMG1 0.45 7.06 0.36 9.05e-12 Cognitive function; LIHC cis rs425277 0.561 rs925906 chr1:2044054 A/C cg04315214 chr1:2043799 PRKCZ 0.46 7.4 0.37 1.08e-12 Height; LIHC cis rs611744 0.647 rs587340 chr8:109246032 C/A cg21045802 chr8:109455806 TTC35 0.59 10.3 0.49 7.86e-22 Dupuytren's disease; LIHC cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg04944784 chr2:26401820 FAM59B -0.72 -9.14 -0.44 5.77e-18 Gut microbiome composition (summer); LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg04267008 chr7:1944627 MAD1L1 0.66 11.11 0.52 1.05e-24 Bipolar disorder and schizophrenia; LIHC cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg26116260 chr4:7069785 GRPEL1 1.0 18.39 0.71 5.24e-53 Monocyte percentage of white cells; LIHC cis rs9916302 0.851 rs7225096 chr17:37664443 T/C cg03013999 chr17:37608204 MED1 0.35 5.76 0.3 1.84e-8 Glomerular filtration rate (creatinine); LIHC trans rs1422110 0.543 rs10035841 chr5:85419597 T/C cg01787110 chr1:109008453 NBPF6 0.28 6.41 0.33 4.76e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs7224737 1.000 rs731152 chr17:40279680 G/A cg00647820 chr17:40259828 DHX58 -0.28 -5.78 -0.3 1.67e-8 Fibrinogen levels; LIHC cis rs9916302 0.706 rs7208252 chr17:37584368 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -12.11 -0.55 2.54e-28 Glomerular filtration rate (creatinine); LIHC cis rs1451375 0.617 rs2876829 chr7:50566762 A/G cg14593290 chr7:50529359 DDC 0.6 9.78 0.47 4.5e-20 Malaria; LIHC cis rs2204008 0.840 rs7136347 chr12:38453531 G/A cg26384229 chr12:38710491 ALG10B 0.91 11.67 0.53 1.01e-26 Bladder cancer; LIHC cis rs965469 1.000 rs6051753 chr20:3315513 G/A cg25506879 chr20:3388711 C20orf194 -0.6 -6.9 -0.35 2.57e-11 IFN-related cytopenia; LIHC cis rs7520050 0.966 rs34102169 chr1:46424864 G/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.42 6.24 0.32 1.27e-9 Red blood cell count;Reticulocyte count; LIHC cis rs4478037 0.822 rs4320035 chr3:33113697 C/G cg16652328 chr3:33138982 GLB1;TMPPE 0.56 7.15 0.36 5.29e-12 Major depressive disorder; LIHC cis rs3818285 0.504 rs1973972 chr10:111651133 A/T cg00817464 chr10:111662876 XPNPEP1 0.46 7.36 0.37 1.4e-12 Superior crus of antihelix expression; LIHC cis rs2250402 0.510 rs7535 chr15:40328575 G/C cg10636054 chr15:40330586 SRP14 0.65 7.85 0.39 5.32e-14 Corneal curvature; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01287788 chr2:86362935 SNORD94;PTCD3 0.41 6.85 0.35 3.41e-11 Cognitive function; LIHC cis rs11864453 0.647 rs2550035 chr16:72113416 C/G cg01557791 chr16:72042693 DHODH -0.39 -6.48 -0.33 3.29e-10 Fibrinogen levels; LIHC cis rs8081395 0.741 rs180530 chr17:58003594 G/A cg13753209 chr17:57696993 CLTC 0.39 5.95 0.31 6.59e-9 White blood cell count; LIHC cis rs4930103 0.508 rs217205 chr11:1973205 T/C cg23202291 chr11:1979235 NA -0.52 -6.67 -0.34 1.05e-10 DNA methylation (parent-of-origin);DNA methylation (variation); LIHC cis rs7917772 0.636 rs10786708 chr10:104526245 C/T cg22532475 chr10:104410764 TRIM8 -0.36 -6.52 -0.33 2.52e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9303280 0.806 rs2872507 chr17:38040763 C/T cg11212589 chr17:38028394 ZPBP2 0.32 6.47 0.33 3.34e-10 Self-reported allergy; LIHC cis rs6426558 0.537 rs6682642 chr1:227244600 G/T cg10327440 chr1:227177885 CDC42BPA 0.46 7.61 0.38 2.68e-13 Neutrophil percentage of white cells; LIHC cis rs13394619 0.935 rs6746291 chr2:11728381 T/C cg07314298 chr2:11723111 GREB1 -0.53 -10.51 -0.49 1.43e-22 Endometriosis; LIHC cis rs539514 0.664 rs1323712 chr13:76300085 C/G cg04757411 chr13:76259545 LMO7 -0.47 -8.39 -0.41 1.27e-15 Type 1 diabetes; LIHC cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg24675658 chr1:53192096 ZYG11B 0.58 9.13 0.44 6.03e-18 Monocyte count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04718845 chr6:152623094 SYNE1 0.44 6.06 0.31 3.64e-9 Pancreatic cancer; LIHC cis rs1707322 0.721 rs4609469 chr1:46117185 C/T cg03146154 chr1:46216737 IPP 0.58 10.27 0.49 9.45e-22 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs4555082 0.874 rs1882846 chr14:105717448 G/C cg13114125 chr14:105738426 BRF1 -0.74 -9.82 -0.47 3.28e-20 Mean platelet volume;Platelet distribution width; LIHC trans rs13315591 1.000 rs13315591 chr3:58556841 A/G cg16863673 chr2:240905040 NDUFA10 0.75 6.09 0.31 3.12e-9 Rheumatoid arthritis; LIHC cis rs10504073 0.647 rs55920380 chr8:50026353 G/A cg00325661 chr8:49890786 NA 0.33 7.4 0.37 1.04e-12 Blood metabolite ratios; LIHC cis rs2239815 0.515 rs9625600 chr22:29244395 T/C cg15103426 chr22:29168792 CCDC117 0.44 5.85 0.3 1.18e-8 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; LIHC trans rs600324 0.598 rs384167 chr6:160476267 A/G cg09580072 chr10:134113312 STK32C -0.33 -6.38 -0.33 5.92e-10 Blood protein levels; LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg21248554 chr2:27665150 KRTCAP3 -0.45 -6.23 -0.32 1.39e-9 Total body bone mineral density; LIHC cis rs2073300 0.609 rs74809795 chr20:23372383 A/C cg16736954 chr20:23401023 NAPB 0.71 8.25 0.41 3.51e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs765787 0.530 rs16941017 chr15:45543281 T/C cg25801113 chr15:45476975 SHF 0.37 6.26 0.32 1.17e-9 Uric acid levels; LIHC cis rs3806843 0.735 rs778597 chr5:140040665 A/G cg19875535 chr5:140030758 IK 0.41 6.7 0.34 8.36e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs6964587 0.692 rs10271430 chr7:91710466 G/C cg17063962 chr7:91808500 NA 0.66 11.76 0.54 4.65e-27 Breast cancer; LIHC cis rs1005277 0.579 rs1548255 chr10:38417193 T/C cg25427524 chr10:38739819 LOC399744 -0.65 -12.38 -0.56 2.36e-29 Extrinsic epigenetic age acceleration; LIHC cis rs651907 0.557 rs12629954 chr3:101360623 C/A cg11279151 chr3:101281821 RG9MTD1 -0.39 -6.0 -0.31 4.96e-9 Colorectal cancer; LIHC cis rs5769765 0.837 rs7284417 chr22:50314346 A/G cg02269571 chr22:50332266 NA -0.61 -8.63 -0.42 2.37e-16 Schizophrenia; LIHC cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg18876405 chr7:65276391 NA -0.54 -9.17 -0.44 4.6e-18 Aortic root size; LIHC cis rs35110281 0.641 rs9983670 chr21:45083425 A/G cg21573476 chr21:45109991 RRP1B -0.59 -11.18 -0.52 6.03e-25 Mean corpuscular volume; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04856096 chr8:68255097 ARFGEF1 0.52 7.79 0.39 7.8500000000000006e-14 Cognitive function; LIHC cis rs826838 0.934 rs10875647 chr12:38856995 G/A cg26384229 chr12:38710491 ALG10B 0.98 13.29 0.58 8.46e-33 Heart rate; LIHC cis rs11098499 0.820 rs12503082 chr4:120284317 A/G cg09307838 chr4:120376055 NA 0.64 9.72 0.47 7.27e-20 Corneal astigmatism; LIHC cis rs2836950 0.501 rs2070865 chr21:40715519 C/T cg06238570 chr21:40685208 BRWD1 -0.39 -6.12 -0.31 2.53e-9 Menarche (age at onset); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg19701416 chr10:28592092 NA 0.46 6.85 0.35 3.55e-11 Pancreatic cancer; LIHC cis rs6570726 0.935 rs385185 chr6:145814992 A/G cg23711669 chr6:146136114 FBXO30 0.55 9.84 0.47 2.69e-20 Lobe attachment (rater-scored or self-reported); LIHC cis rs600806 0.821 rs4970840 chr1:109873367 A/G cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.25 -0.36 2.8e-12 Intelligence (multi-trait analysis); LIHC cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg26566898 chr11:117069891 TAGLN 0.47 7.46 0.37 7.34e-13 Blood protein levels; LIHC cis rs2404602 0.684 rs11072600 chr15:76867915 T/C cg03037974 chr15:76606532 NA -0.61 -10.3 -0.49 7.81e-22 Blood metabolite levels; LIHC trans rs11148252 0.532 rs9526975 chr13:53255804 C/T cg18335740 chr13:41363409 SLC25A15 0.54 9.73 0.47 6.72e-20 Lewy body disease; LIHC cis rs3736485 0.966 rs7177720 chr15:51890282 T/C cg08986416 chr15:51914746 DMXL2 -0.42 -6.37 -0.33 5.94e-10 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs1577917 0.917 rs1579886 chr6:86557191 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.07 -0.4 1.22e-14 Response to antipsychotic treatment; LIHC cis rs9325144 0.505 rs7955162 chr12:38711658 G/A cg13010199 chr12:38710504 ALG10B 0.47 7.44 0.37 8.47e-13 Morning vs. evening chronotype; LIHC cis rs35110281 0.693 rs2838345 chr21:45092715 C/T cg21573476 chr21:45109991 RRP1B -0.57 -10.98 -0.51 3.03e-24 Mean corpuscular volume; LIHC cis rs5769765 0.955 rs9616366 chr22:50301178 C/T cg02269571 chr22:50332266 NA -0.62 -8.78 -0.43 7.76e-17 Schizophrenia; LIHC cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.44 7.54 0.38 4.16e-13 Electroencephalogram traits; LIHC cis rs1577917 1.000 rs884841 chr6:86680300 A/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.4 -6.55 -0.33 2.1e-10 Response to antipsychotic treatment; LIHC cis rs752010 0.875 rs11210502 chr1:42093712 A/C cg06885757 chr1:42089581 HIVEP3 0.29 6.15 0.32 2.11e-9 Lupus nephritis in systemic lupus erythematosus; LIHC cis rs1005277 0.579 rs2749612 chr10:38488610 G/A cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg18357526 chr6:26021779 HIST1H4A 0.61 8.56 0.42 3.88e-16 Blood metabolite levels; LIHC cis rs35110281 0.591 rs86138 chr21:44932398 G/A cg04455712 chr21:45112962 RRP1B 0.45 7.78 0.39 8.42e-14 Mean corpuscular volume; LIHC cis rs7223966 0.960 rs7212379 chr17:61706122 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.82 0.35 4.06e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs875971 0.862 rs28491091 chr7:65669064 G/T cg18876405 chr7:65276391 NA -0.35 -6.39 -0.33 5.29e-10 Aortic root size; LIHC cis rs2033711 0.870 rs1051500 chr19:58944402 A/G cg00825309 chr19:58991885 ZNF446 -0.64 -10.19 -0.48 1.8e-21 Uric acid clearance; LIHC cis rs10911232 0.507 rs3935384 chr1:183028970 C/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.6 0.5 6.95e-23 Hypertriglyceridemia; LIHC cis rs2832191 0.716 rs7284006 chr21:30475186 T/A cg08807101 chr21:30365312 RNF160 0.78 12.08 0.55 3.06e-28 Dental caries; LIHC cis rs10916814 0.632 rs10799646 chr1:20903985 G/T cg24502330 chr1:20914028 CDA -0.31 -6.76 -0.34 5.86e-11 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs7223966 1.000 rs28463311 chr17:61919643 C/T cg05941027 chr17:61774174 LIMD2 0.37 7.68 0.38 1.7e-13 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs10911363 0.592 rs2702203 chr1:183462513 A/T cg09173681 chr1:183549694 NCF2 0.53 9.36 0.45 1.08e-18 Systemic lupus erythematosus; LIHC cis rs2274273 0.870 rs28716725 chr14:55816610 T/C cg01864836 chr14:55583639 NA -0.4 -7.52 -0.38 4.98e-13 Protein biomarker; LIHC cis rs7017697 1.000 rs2410612 chr8:19681647 A/G cg03894339 chr8:19674705 INTS10 0.53 8.57 0.42 3.68e-16 Breast cancer; LIHC cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg05185784 chr16:90016020 DEF8 -0.44 -5.97 -0.31 5.84e-9 Interleukin-17 levels; LIHC cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg07092213 chr7:1199455 ZFAND2A -0.47 -7.31 -0.37 1.9e-12 Longevity;Endometriosis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg26462239 chr17:45608823 NPEPPS 0.42 6.33 0.32 7.76e-10 Pancreatic cancer; LIHC cis rs2760061 0.583 rs708124 chr1:228220771 A/T cg02753203 chr1:228287806 NA 0.71 12.44 0.56 1.44e-29 Diastolic blood pressure; LIHC cis rs5370 0.730 rs3756865 chr6:12288426 T/G cg27565517 chr6:12292676 EDN1 0.34 5.9 0.3 8.64e-9 Circulating vasoactive peptide levels; LIHC cis rs2228479 0.850 rs17226512 chr16:89839976 T/C cg19635926 chr16:89946313 TCF25 0.49 6.38 0.33 5.81e-10 Skin colour saturation; LIHC cis rs311392 0.902 rs413667 chr8:55091908 C/A cg20636351 chr8:55087400 NA -0.37 -7.65 -0.38 2.13e-13 Pelvic organ prolapse (moderate/severe); LIHC cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg25894440 chr7:65020034 NA -0.51 -5.82 -0.3 1.34e-8 Diabetic kidney disease; LIHC cis rs7582720 1.000 rs79539678 chr2:203740938 G/C cg15057621 chr2:203777863 WDR12;ALS2CR8 0.78 6.42 0.33 4.42e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg17178900 chr1:205818956 PM20D1 0.75 11.21 0.52 4.77e-25 Menarche (age at onset); LIHC cis rs2576037 0.583 rs504668 chr18:44410749 T/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.88 0.51 7.24e-24 Personality dimensions; LIHC cis rs7131987 0.650 rs12366527 chr12:29474256 C/G cg12903224 chr12:29470962 FAR2 -0.41 -6.65 -0.34 1.14e-10 QT interval; LIHC cis rs8180040 0.932 rs62246474 chr3:47398130 C/T cg16586182 chr3:47516702 SCAP 0.58 10.69 0.5 3.43e-23 Colorectal cancer; LIHC cis rs5758511 0.633 rs5758689 chr22:42664972 T/G cg00645731 chr22:42541494 CYP2D7P1 0.52 8.23 0.41 4.11e-15 Birth weight; LIHC cis rs5769765 0.505 rs4561759 chr22:50256686 C/T cg02269571 chr22:50332266 NA 0.7 8.05 0.4 1.38e-14 Schizophrenia; LIHC cis rs1801251 1.000 rs12987513 chr2:233622066 A/G cg25237894 chr2:233734115 C2orf82 0.57 11.11 0.51 1.08e-24 Coronary artery disease; LIHC cis rs887797 0.576 rs9914573 chr17:64591389 A/G cg27019712 chr17:64599478 PRKCA -0.4 -6.86 -0.35 3.22e-11 Possible neuropathic pain in post total joint replacement surgery for osteoarthritis; LIHC cis rs9814567 1.000 rs13089966 chr3:134279197 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 0.42 6.1 0.31 2.85e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2439831 0.867 rs933941 chr15:43632226 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.75 10.93 0.51 4.73e-24 Lung cancer in ever smokers; LIHC cis rs9611565 0.571 rs7364123 chr22:42216326 A/G cg03806693 chr22:41940476 POLR3H -0.72 -7.81 -0.39 6.88e-14 Vitiligo; LIHC cis rs6545883 0.859 rs35760550 chr2:61603865 T/A cg15711740 chr2:61764176 XPO1 0.42 5.74 0.3 2.14e-8 Tuberculosis; LIHC cis rs78456975 1.000 rs10189336 chr2:1558015 G/A cg01028140 chr2:1542097 TPO -0.56 -6.7 -0.34 8.84e-11 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs1559088 0.600 rs58173463 chr19:33596749 C/T cg03563238 chr19:33554763 RHPN2 -0.31 -5.78 -0.3 1.65e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7020830 0.898 rs7038219 chr9:37182892 C/A cg14294708 chr9:37120828 ZCCHC7 1.05 23.05 0.78 1.31e-71 Schizophrenia; LIHC cis rs17106184 1.000 rs12067513 chr1:51310062 G/A cg07174182 chr1:51127561 FAF1 -0.62 -6.59 -0.34 1.68e-10 Type 2 diabetes; LIHC cis rs929354 0.772 rs1182364 chr7:157017912 T/C cg05182265 chr7:156933206 UBE3C 0.33 6.3 0.32 9.38e-10 Body mass index; LIHC cis rs8072100 0.935 rs8070759 chr17:45638760 C/T cg08085267 chr17:45401833 C17orf57 0.39 5.85 0.3 1.15e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs9549367 0.789 rs9549361 chr13:113898329 C/T cg00898013 chr13:113819073 PROZ 0.4 7.01 0.35 1.27e-11 Platelet distribution width; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg16634193 chr10:135207476 MTG1 -0.53 -6.05 -0.31 3.71e-9 Systolic blood pressure; LIHC cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs1552244 0.882 rs17081288 chr3:10042113 A/G cg00149659 chr3:10157352 C3orf10 0.53 6.03 0.31 4.28e-9 Alzheimer's disease; LIHC trans rs7246657 0.943 rs10426666 chr19:37828514 C/G cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs12744310 1.000 rs12024413 chr1:41756416 A/G cg03962019 chr1:41807865 NA 0.38 6.1 0.31 2.82e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs7618501 0.932 rs4855850 chr3:49761571 G/A cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs2180341 0.751 rs9388553 chr6:127574044 A/G cg24812749 chr6:127587940 RNF146 0.74 10.83 0.51 1.08e-23 Breast cancer; LIHC cis rs7568458 0.709 rs2592551 chr2:85780131 G/A cg02493740 chr2:85810744 VAMP5 -0.48 -7.97 -0.4 2.43e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4919087 0.561 rs10082521 chr10:99070526 A/T cg25902810 chr10:99078978 FRAT1 -0.6 -7.09 -0.36 7.76e-12 Monocyte count; LIHC cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 9.57 0.46 2.27e-19 Platelet count; LIHC cis rs1023500 0.505 rs134899 chr22:42683030 T/G cg15557168 chr22:42548783 NA -0.36 -6.14 -0.32 2.29e-9 Schizophrenia; LIHC cis rs6540556 0.723 rs11119336 chr1:209930585 G/C cg05527609 chr1:210001259 C1orf107 -0.69 -10.01 -0.48 7.56e-21 Red blood cell count; LIHC cis rs7845219 0.544 rs7016078 chr8:95922615 G/A cg16049864 chr8:95962084 TP53INP1 -0.45 -6.76 -0.34 6.11e-11 Type 2 diabetes; LIHC cis rs2239547 0.603 rs12489490 chr3:53064022 C/A cg11645453 chr3:52864694 ITIH4 0.26 6.01 0.31 4.66e-9 Schizophrenia; LIHC cis rs9733 0.519 rs1134067 chr1:150721175 G/T cg17724175 chr1:150552817 MCL1 0.51 10.12 0.48 3.24e-21 Tonsillectomy; LIHC cis rs9811920 0.609 rs6440938 chr3:99652092 T/C cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.74 -0.3 2.12e-8 Axial length; LIHC cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg10755058 chr3:40428713 ENTPD3 -0.41 -7.23 -0.36 3.11e-12 Renal cell carcinoma; LIHC cis rs7727544 0.735 rs272881 chr5:131669264 G/A cg24060327 chr5:131705240 SLC22A5 -0.59 -8.44 -0.42 9.19e-16 Blood metabolite levels; LIHC cis rs12142240 0.698 rs61519400 chr1:46855298 A/G cg14993813 chr1:46806288 NSUN4 -0.66 -5.94 -0.31 6.85e-9 Menopause (age at onset); LIHC cis rs2072499 0.750 rs55675376 chr1:156165881 C/T cg24450063 chr1:156163899 SLC25A44 0.76 8.09 0.4 1.06e-14 Testicular germ cell tumor; LIHC cis rs9322817 0.691 rs4142531 chr6:105324811 G/A cg02098413 chr6:105308735 HACE1 0.41 7.7 0.38 1.49e-13 Thyroid stimulating hormone; LIHC cis rs72615157 0.613 rs56089143 chr7:99819844 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.55 6.09 0.31 2.98e-9 Lung function (FEV1/FVC); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg25825726 chr19:6230459 MLLT1 0.45 6.11 0.31 2.74e-9 Hepatitis; LIHC cis rs600806 0.893 rs370088 chr1:109858119 T/C cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.25 -0.36 2.8e-12 Intelligence (multi-trait analysis); LIHC cis rs9660992 0.736 rs55673946 chr1:205250475 T/C cg21545522 chr1:205238299 TMCC2 0.34 6.73 0.34 7.03e-11 Mean corpuscular volume;Mean platelet volume; LIHC cis rs477895 1.000 rs34292685 chr11:64049021 C/T cg18225595 chr11:63971243 STIP1 0.62 6.68 0.34 9.77e-11 Mean platelet volume; LIHC cis rs2574704 0.851 rs2574717 chr3:11661280 A/C cg15876825 chr3:11651881 VGLL4 -0.5 -8.09 -0.4 1.06e-14 Body mass index; LIHC cis rs10911232 0.560 rs10911221 chr1:183046737 G/C ch.1.3577855R chr1:183094577 LAMC1 0.57 9.84 0.47 2.84e-20 Hypertriglyceridemia; LIHC cis rs7208859 0.623 rs73271872 chr17:29152228 C/G cg13385521 chr17:29058706 SUZ12P 0.83 8.0 0.4 1.97e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12142240 0.698 rs6679898 chr1:46820589 A/C cg00530320 chr1:46809349 NSUN4 0.53 5.71 0.3 2.43e-8 Menopause (age at onset); LIHC cis rs2895526 0.540 rs12412190 chr10:12714721 A/G cg00115178 chr10:12648176 CAMK1D -0.39 -6.9 -0.35 2.5e-11 Headache; LIHC cis rs36051895 0.659 rs3780366 chr9:5068596 T/C cg02405213 chr9:5042618 JAK2 -0.65 -10.63 -0.5 5.36e-23 Pediatric autoimmune diseases; LIHC cis rs7635838 1.000 rs7635838 chr3:11412604 A/G cg00170343 chr3:11313890 ATG7 0.43 6.92 0.35 2.18e-11 HDL cholesterol; LIHC cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg08219700 chr8:58056026 NA 0.52 7.13 0.36 6.14e-12 Developmental language disorder (linguistic errors); LIHC cis rs2842992 0.915 rs1967802 chr6:160097791 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.71 12.01 0.54 5.67e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg06634786 chr22:41940651 POLR3H -0.77 -7.75 -0.39 1.09e-13 Vitiligo; LIHC cis rs7512552 0.803 rs13294 chr1:150484987 G/A cg15654264 chr1:150340011 RPRD2 0.71 11.22 0.52 4.25e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs929354 0.742 rs10274687 chr7:156933181 T/G cg16102536 chr7:156981717 UBE3C 0.35 5.88 0.3 9.55e-9 Body mass index; LIHC cis rs240764 0.817 rs239216 chr6:101147892 T/G cg09795085 chr6:101329169 ASCC3 0.52 7.13 0.36 5.92e-12 Neuroticism; LIHC trans rs11098499 0.954 rs7437420 chr4:120312903 A/G cg25214090 chr10:38739885 LOC399744 0.55 8.7 0.43 1.41e-16 Corneal astigmatism; LIHC cis rs60871478 1.000 rs62432253 chr7:802928 A/G cg05535760 chr7:792225 HEATR2 0.93 12.64 0.56 2.67e-30 Cerebrospinal P-tau181p levels; LIHC cis rs2404602 0.735 rs2280306 chr15:76652258 C/G cg03037974 chr15:76606532 NA -0.65 -11.48 -0.53 4.96e-26 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24303698 chr19:46367351 SYMPK;FOXA3 0.5 6.64 0.34 1.2e-10 Lung function (FEV1/FVC); LIHC cis rs9916302 0.808 rs6503515 chr17:37606433 G/T cg03013999 chr17:37608204 MED1 0.35 5.89 0.3 9.2e-9 Glomerular filtration rate (creatinine); LIHC cis rs11098499 0.575 rs907205 chr4:120238664 G/C cg09307838 chr4:120376055 NA 0.71 11.01 0.51 2.43e-24 Corneal astigmatism; LIHC cis rs10489202 1.000 rs66950781 chr1:168018779 C/A cg24449463 chr1:168025552 DCAF6 -0.52 -6.55 -0.33 2.1e-10 Schizophrenia; LIHC cis rs7618501 0.633 rs7628058 chr3:50039474 C/T cg24110177 chr3:50126178 RBM5 -0.47 -7.58 -0.38 3.18e-13 Intelligence (multi-trait analysis); LIHC cis rs7020830 0.823 rs7019699 chr9:37125081 C/A cg14294708 chr9:37120828 ZCCHC7 1.19 28.2 0.84 3.06e-91 Schizophrenia; LIHC cis rs782590 0.764 rs2586970 chr2:55829967 A/G cg03859395 chr2:55845619 SMEK2 0.72 11.75 0.54 5.37e-27 Metabolic syndrome; LIHC cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg04944784 chr2:26401820 FAM59B -0.77 -9.59 -0.46 1.92e-19 Gut microbiome composition (summer); LIHC cis rs796364 0.760 rs1569178 chr2:201024512 T/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.66 -0.34 1.13e-10 Schizophrenia; LIHC cis rs2073499 1.000 rs2071803 chr3:50407344 G/T cg12708802 chr3:50388878 TUSC4;CYB561D2 0.6 6.53 0.33 2.42e-10 Schizophrenia; LIHC cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg25894440 chr7:65020034 NA -0.52 -6.12 -0.31 2.57e-9 Diabetic kidney disease; LIHC cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg20607798 chr8:58055168 NA 0.6 7.23 0.36 3.15e-12 Developmental language disorder (linguistic errors); LIHC cis rs10865541 0.902 rs12474836 chr2:3418874 A/G cg11642891 chr2:3452563 TTC15 -0.45 -7.2 -0.36 3.8e-12 Obesity-related traits; LIHC cis rs9309473 0.607 rs12478346 chr2:73584360 C/T cg20560298 chr2:73613845 ALMS1 -0.45 -7.2 -0.36 3.76e-12 Metabolite levels; LIHC cis rs9916302 0.784 rs4795361 chr17:37573446 G/A cg07936489 chr17:37558343 FBXL20 -0.84 -13.41 -0.59 2.95e-33 Glomerular filtration rate (creatinine); LIHC cis rs4819052 0.765 rs2838852 chr21:46677037 C/A cg22633049 chr21:46681294 NA -0.35 -6.01 -0.31 4.85e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg03806693 chr22:41940476 POLR3H 0.97 10.24 0.48 1.17e-21 Crohn's disease;Inflammatory bowel disease; LIHC cis rs9473924 0.542 rs2857482 chr6:50790642 C/T cg14470998 chr6:50812995 TFAP2B 1.05 9.43 0.45 6.33e-19 Body mass index; LIHC trans rs561341 0.714 rs547473 chr17:30297560 T/G cg20587970 chr11:113659929 NA -1.25 -10.87 -0.51 8.04e-24 Hip circumference adjusted for BMI; LIHC cis rs55665837 1.000 rs11023216 chr11:14437153 G/A cg19336497 chr11:14380999 RRAS2 -0.46 -8.5 -0.42 5.75e-16 Vitamin D levels; LIHC trans rs2288327 0.643 rs16866334 chr2:179336672 A/G cg14011486 chr1:26737247 LIN28 0.63 8.99 0.44 1.72e-17 Atrial fibrillation; LIHC cis rs56163509 1 rs56163509 chr16:28864471 A/G cg16576597 chr16:28551801 NUPR1 0.37 5.83 0.3 1.26e-8 Tonsillectomy;Mean corpuscular volume; LIHC cis rs9902453 0.780 rs57037139 chr17:28173283 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 12.32 0.55 4.05e-29 Coffee consumption (cups per day); LIHC cis rs17384381 1.000 rs1608536 chr1:85885836 C/T cg16011679 chr1:85725395 C1orf52 0.8 8.45 0.42 8.66e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs2839186 0.596 rs4819217 chr21:47644092 G/T cg00815214 chr21:47717953 NA -0.37 -6.26 -0.32 1.17e-9 Testicular germ cell tumor; LIHC trans rs1814175 0.869 rs10769600 chr11:49681832 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -21.86 -0.76 6.73e-67 Height; LIHC cis rs17854409 0.803 rs1063247 chr20:61472118 C/G cg06598544 chr20:61472147 COL9A3 -0.9 -8.42 -0.41 1.07e-15 Obesity-related traits; LIHC cis rs780096 0.546 rs715325 chr2:27725572 C/A cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.82 -0.3 1.37e-8 Total body bone mineral density; LIHC cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg13395646 chr4:1353034 KIAA1530 -0.64 -9.03 -0.44 1.25e-17 Obesity-related traits; LIHC cis rs6089584 0.606 rs7270469 chr20:60577258 G/A cg06108461 chr20:60628389 TAF4 -0.51 -6.83 -0.35 3.94e-11 Body mass index; LIHC cis rs3791556 0.853 rs35245395 chr2:240107661 C/T cg03281426 chr2:240109471 HDAC4 0.39 6.2 0.32 1.67e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs2016586 0.796 rs1997884 chr22:36103778 G/A cg26342177 chr22:36113512 APOL5 -0.39 -6.68 -0.34 9.63e-11 Body mass index; LIHC cis rs243505 0.516 rs55988390 chr7:148582535 C/T cg09806900 chr7:148480153 CUL1 0.44 6.2 0.32 1.63e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6783573 0.711 rs3806701 chr3:46617337 G/A cg16875182 chr3:46619291 LRRC2;TDGF1 -0.55 -6.45 -0.33 3.89e-10 Cerebrospinal fluid biomarker levels; LIHC cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg00290607 chr11:67383545 NA 0.38 5.75 0.3 1.99e-8 Mean corpuscular volume; LIHC cis rs6788895 1.000 rs16862842 chr3:150484844 A/G cg07663535 chr3:150480033 SIAH2 0.56 7.1 0.36 7.3e-12 Breast cancer; LIHC cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 8.77 0.43 8.86e-17 Colonoscopy-negative controls vs population controls; LIHC trans rs208520 0.802 rs208516 chr6:66946119 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.69 -7.6 -0.38 2.95e-13 Exhaled nitric oxide output; LIHC cis rs2806561 0.754 rs10917344 chr1:23342193 C/G cg19743168 chr1:23544995 NA -0.37 -6.76 -0.34 5.87e-11 Height; LIHC cis rs11098499 0.863 rs7657849 chr4:120455494 T/C cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg23248424 chr5:179741104 GFPT2 -0.44 -6.59 -0.34 1.63e-10 Height; LIHC cis rs4243830 1.000 rs12047931 chr1:6587614 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 0.87 7.7 0.38 1.51e-13 Body mass index; LIHC cis rs1538970 0.816 rs11211124 chr1:45962409 T/C cg24296786 chr1:45957014 TESK2 -0.51 -7.54 -0.38 4.36e-13 Platelet count; LIHC cis rs597539 0.652 rs553875 chr11:68695144 T/G cg04772025 chr11:68637568 NA 0.5 6.36 0.33 6.36e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6545883 0.931 rs12713437 chr2:61722904 C/T cg15711740 chr2:61764176 XPO1 -0.42 -5.88 -0.3 9.61e-9 Tuberculosis; LIHC cis rs9814567 1.000 rs62271514 chr3:134298554 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.24 0.55 8.15e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs798554 0.616 rs1636252 chr7:2884993 A/C cg04166393 chr7:2884313 GNA12 0.37 6.09 0.31 3.06e-9 Height; LIHC cis rs763121 0.813 rs4821807 chr22:39065582 A/G cg06022373 chr22:39101656 GTPBP1 0.62 10.8 0.5 1.34e-23 Menopause (age at onset); LIHC cis rs11690935 0.959 rs4667694 chr2:172605399 G/A cg13550731 chr2:172543902 DYNC1I2 -0.94 -17.95 -0.7 3.27e-51 Schizophrenia; LIHC cis rs916888 0.773 rs199447 chr17:44812188 C/T cg15921436 chr17:44337874 NA 0.64 6.49 0.33 3.07e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs6076065 0.748 rs2180139 chr20:23405281 G/A cg11657817 chr20:23433608 CST11 0.31 6.73 0.34 7.13e-11 Facial morphology (factor 15, philtrum width); LIHC cis rs4803468 0.967 rs16975238 chr19:41944985 T/A cg14132834 chr19:41945861 ATP5SL 0.44 6.49 0.33 3e-10 Height; LIHC cis rs6088580 0.634 rs2225837 chr20:33005634 C/T cg08999081 chr20:33150536 PIGU -0.67 -13.28 -0.58 9.76e-33 Glomerular filtration rate (creatinine); LIHC cis rs929354 0.742 rs7784442 chr7:156934475 G/C cg16102536 chr7:156981717 UBE3C 0.35 5.82 0.3 1.33e-8 Body mass index; LIHC cis rs861318 0.938 rs12124059 chr1:159026639 T/C cg11003133 chr1:159046391 AIM2 -0.33 -6.63 -0.34 1.34e-10 Obesity-related traits; LIHC cis rs10876993 0.890 rs4760165 chr12:58063801 C/T cg18357645 chr12:58087776 OS9 0.52 8.47 0.42 7.38e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs11792861 0.855 rs116127510 chr9:111868344 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.64e-16 Menarche (age at onset); LIHC cis rs4474465 1.000 rs908003 chr11:78190340 A/T cg27205649 chr11:78285834 NARS2 -0.38 -5.78 -0.3 1.69e-8 Alzheimer's disease (survival time); LIHC cis rs67460515 0.563 rs1599375 chr3:160897771 C/T cg03342759 chr3:160939853 NMD3 0.59 9.1 0.44 7.63e-18 Parkinson's disease; LIHC cis rs4820539 1.000 rs2267002 chr22:23456702 T/C cg14186256 chr22:23484241 RTDR1 0.91 18.64 0.71 5.03e-54 Bone mineral density; LIHC cis rs7223966 1.000 rs8064261 chr17:61705212 G/A cg05941027 chr17:61774174 LIMD2 0.35 7.19 0.36 4.05e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs7246865 0.954 rs10427132 chr19:17207156 T/G cg16202187 chr19:17186497 HAUS8;MYO9B 0.4 6.04 0.31 4.12e-9 Reticulocyte fraction of red cells; LIHC trans rs73245065 0.681 rs67056170 chr10:30911101 T/C cg21500456 chr14:21190377 NA 0.45 6.23 0.32 1.37e-9 Bone mineral density (femoral neck); LIHC cis rs9868809 0.772 rs9877794 chr3:48718388 G/C cg07636037 chr3:49044803 WDR6 -0.56 -6.32 -0.32 8.37e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC trans rs1499614 1.000 rs2707832 chr7:66136549 C/T cg07424592 chr7:64974309 NA 0.73 8.8 0.43 6.92e-17 Gout; LIHC cis rs1385374 0.800 rs12321679 chr12:129284791 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.59 7.03 0.36 1.11e-11 Systemic lupus erythematosus; LIHC cis rs8103278 1.000 rs725660 chr19:46262286 C/A cg02376097 chr19:46275166 DMPK -0.47 -7.5 -0.38 5.41e-13 Coronary artery disease; LIHC cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg10755058 chr3:40428713 ENTPD3 -0.4 -6.91 -0.35 2.38e-11 Renal cell carcinoma; LIHC cis rs12893668 0.572 rs4906350 chr14:104111794 C/T cg24130564 chr14:104152367 KLC1 -0.56 -9.6 -0.46 1.78e-19 Reticulocyte count; LIHC cis rs2386661 0.523 rs61832677 chr10:5652477 A/G cg17085576 chr10:5658249 NA -0.3 -5.85 -0.3 1.15e-8 Breast cancer; LIHC cis rs1003719 0.679 rs2246285 chr21:38582431 G/A cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.37 -0.49 4.2e-22 Eye color traits; LIHC cis rs7312933 0.703 rs10459290 chr12:42613290 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.51 7.37 0.37 1.32e-12 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg22963979 chr7:1858916 MAD1L1 -0.42 -6.89 -0.35 2.74e-11 Bipolar disorder and schizophrenia; LIHC cis rs539514 0.664 rs479824 chr13:76308360 C/T cg04757411 chr13:76259545 LMO7 -0.42 -7.31 -0.37 1.89e-12 Type 1 diabetes; LIHC cis rs9443189 0.570 rs661229 chr6:76293793 G/A cg01950844 chr6:76311363 SENP6 0.91 11.43 0.53 7.43e-26 Prostate cancer; LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs7927771 0.725 rs11570094 chr11:47359706 A/C cg20135002 chr11:47629003 NA 0.38 6.23 0.32 1.38e-9 Subjective well-being; LIHC cis rs55702914 0.809 rs3097385 chr2:198199297 G/A cg10820045 chr2:198174542 NA -0.41 -5.96 -0.31 6.21e-9 Major depression and alcohol dependence; LIHC cis rs933688 0.526 rs7727632 chr5:90609009 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 -0.41 -6.23 -0.32 1.35e-9 Smoking behavior; LIHC cis rs9814567 1.000 rs13096604 chr3:134250099 G/T cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.79 0.3 1.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs876084 0.505 rs10108373 chr8:121126109 T/C cg06265175 chr8:121136014 COL14A1 0.43 6.92 0.35 2.22e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7223966 1.000 rs11657120 chr17:61857218 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 6.87 0.35 2.98e-11 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9658691 0.607 rs12412701 chr10:90782323 C/T cg03111039 chr10:90751583 FAS;ACTA2 -0.93 -6.71 -0.34 8.01e-11 Mosquito bite size; LIHC cis rs9486715 1.000 rs11153082 chr6:97059666 A/G cg06623918 chr6:96969491 KIAA0776 -0.86 -14.39 -0.61 4.81e-37 Headache; LIHC cis rs2120019 1.000 rs7175720 chr15:75348962 C/G cg09165964 chr15:75287851 SCAMP5 0.61 9.72 0.47 7.27e-20 Blood trace element (Zn levels); LIHC cis rs1506636 1.000 rs2299984 chr7:123356921 G/T cg03229431 chr7:123269106 ASB15 0.57 11.26 0.52 3.17e-25 Plateletcrit;Platelet count; LIHC cis rs4332037 0.538 rs4721164 chr7:1932629 C/G cg23422044 chr7:1970798 MAD1L1 -0.61 -9.49 -0.46 3.96e-19 Bipolar disorder; LIHC cis rs2236918 1.000 rs2236918 chr1:242017826 C/G cg17736920 chr1:242011382 EXO1 -0.59 -8.62 -0.42 2.46e-16 Menopause (age at onset); LIHC cis rs11690935 1.000 rs2138348 chr2:172558172 A/C cg13550731 chr2:172543902 DYNC1I2 0.91 17.31 0.68 1.2e-48 Schizophrenia; LIHC cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg05896524 chr21:47604654 C21orf56 0.45 6.99 0.35 1.46e-11 Testicular germ cell tumor; LIHC cis rs7131987 0.650 rs11050187 chr12:29472876 T/C cg14222432 chr12:29376421 FAR2 0.36 6.96 0.35 1.72e-11 QT interval; LIHC cis rs713477 0.967 rs2152975 chr14:55907919 C/T cg13175173 chr14:55914753 NA -0.35 -8.13 -0.4 7.79e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg20570016 chr1:156261298 TMEM79 0.38 6.11 0.31 2.75e-9 Tonsillectomy; LIHC trans rs1814175 0.616 rs10839342 chr11:49742687 A/C cg18944383 chr4:111397179 ENPEP 0.27 6.94 0.35 1.94e-11 Height; LIHC cis rs240764 0.782 rs7748644 chr6:101166809 T/G cg09795085 chr6:101329169 ASCC3 -0.4 -5.75 -0.3 1.96e-8 Neuroticism; LIHC cis rs6121246 0.529 rs58757492 chr20:30181425 G/A cg13852791 chr20:30311386 BCL2L1 0.7 6.45 0.33 3.83e-10 Mean corpuscular hemoglobin; LIHC cis rs96067 0.805 rs6425966 chr1:36611287 C/T cg24686825 chr1:36642396 MAP7D1 0.53 7.44 0.37 8.31e-13 Corneal structure; LIHC cis rs763121 0.853 rs2072795 chr22:39064209 A/G cg06022373 chr22:39101656 GTPBP1 -0.64 -11.0 -0.51 2.73e-24 Menopause (age at onset); LIHC cis rs712039 0.652 rs829163 chr17:35766026 G/C cg16670864 chr17:35848621 DUSP14 0.34 5.75 0.3 2.02e-8 Tuberculosis; LIHC cis rs8060686 0.565 rs4359427 chr16:68202747 C/T cg05110241 chr16:68378359 PRMT7 -0.53 -6.07 -0.31 3.48e-9 HDL cholesterol;Metabolic syndrome; LIHC trans rs951252 0.504 rs11734405 chr4:146081096 C/T cg15769475 chr17:3960566 ZZEF1 0.48 6.34 0.32 7.15e-10 Hip circumference; LIHC cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg08469215 chr1:156261351 TMEM79 0.4 6.59 0.34 1.68e-10 Tonsillectomy; LIHC cis rs11792861 0.926 rs11787878 chr9:111866749 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.69e-16 Menarche (age at onset); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg03323938 chr19:39663667 PAK4 0.44 6.1 0.31 2.8e-9 Hepatitis; LIHC cis rs1664789 1.000 rs1694065 chr5:53282335 A/C ch.5.1024479R chr5:53302184 ARL15 -0.52 -8.43 -0.41 9.79e-16 Waist circumference adjusted for body mass index; LIHC cis rs6499255 1.000 rs11641521 chr16:69823081 C/G cg15192750 chr16:69999425 NA 0.42 6.39 0.33 5.46e-10 IgE levels; LIHC cis rs919433 0.617 rs700643 chr2:198601370 A/G cg10820045 chr2:198174542 NA 0.49 7.34 0.37 1.56e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs155076 0.711 rs9550724 chr13:21885030 G/T cg14456004 chr13:21872349 NA 1.34 14.5 0.62 1.82e-37 White matter hyperintensity burden; LIHC cis rs7847628 0.765 rs10985024 chr9:123516812 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.74 11.54 0.53 2.93e-26 Birth weight; LIHC cis rs9733 0.596 rs2867304 chr1:150630995 G/A cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs7584330 0.518 rs11903073 chr2:238432766 C/T cg08992911 chr2:238395768 MLPH 0.5 6.02 0.31 4.42e-9 Prostate cancer; LIHC cis rs2075371 0.796 rs12154724 chr7:133943443 G/A cg20476274 chr7:133979776 SLC35B4 0.66 9.09 0.44 8.03e-18 Mean platelet volume; LIHC cis rs7249142 0.549 rs2283623 chr19:19283027 G/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.4 -6.63 -0.34 1.33e-10 IgG glycosylation; LIHC cis rs2816062 0.786 rs2745320 chr1:18893592 G/A cg18795169 chr1:18902165 NA -0.8 -17.92 -0.7 4.15e-51 Urate levels in lean individuals; LIHC cis rs6429082 0.627 rs2016437 chr1:235539355 T/G cg26050004 chr1:235667680 B3GALNT2 -0.47 -7.04 -0.36 1.06e-11 Adiposity; LIHC cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg10802521 chr3:52805072 NEK4 -0.45 -7.59 -0.38 2.99e-13 Bipolar disorder; LIHC trans rs6733379 0.588 rs2193790 chr2:34445953 A/G cg22998206 chr12:49239429 DDX23 0.39 6.17 0.32 1.97e-9 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs34779708 0.966 rs4934536 chr10:35441169 A/G cg04310649 chr10:35416472 CREM -0.43 -5.77 -0.3 1.79e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs793571 0.744 rs12901551 chr15:59160069 A/T cg05156742 chr15:59063176 FAM63B -0.34 -5.87 -0.3 1.04e-8 Schizophrenia; LIHC cis rs12458462 0.665 rs2035085 chr18:77485280 C/T cg11879182 chr18:77439856 CTDP1 0.83 13.37 0.59 4.47e-33 Monocyte count; LIHC cis rs2075371 1.000 rs2598288 chr7:133977304 A/T cg11752832 chr7:134001865 SLC35B4 0.48 7.36 0.37 1.34e-12 Mean platelet volume; LIHC cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.4 0.37 1.08e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs7613875 0.620 rs7634441 chr3:50071677 G/A cg21467203 chr3:49911342 NA 0.52 9.59 0.46 1.95e-19 Body mass index; LIHC cis rs6701037 0.512 rs2285216 chr1:175133012 C/T cg00958927 chr1:175162553 KIAA0040 0.38 6.51 0.33 2.73e-10 Alcohol dependence; LIHC cis rs4638749 0.677 rs10208945 chr2:108838593 G/C cg06795125 chr2:108905320 SULT1C2 -0.3 -6.05 -0.31 3.85e-9 Blood pressure; LIHC cis rs801193 0.967 rs1110414 chr7:66205582 A/G cg18876405 chr7:65276391 NA 0.42 7.32 0.37 1.79e-12 Aortic root size; LIHC cis rs9486719 1.000 rs2142652 chr6:96868504 A/C cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs6121246 0.909 rs6089058 chr20:30326338 T/G cg13852791 chr20:30311386 BCL2L1 0.95 9.72 0.47 6.94e-20 Mean corpuscular hemoglobin; LIHC cis rs12477438 0.735 rs12474477 chr2:99690408 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -16.01 -0.65 1.99e-43 Chronic sinus infection; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06666157 chr19:4791552 FEM1A 0.49 7.53 0.38 4.61e-13 Pancreatic cancer; LIHC cis rs2228479 0.850 rs11076624 chr16:89855749 T/C cg00800038 chr16:89945340 TCF25 -0.6 -8.5 -0.42 5.92e-16 Skin colour saturation; LIHC cis rs2073300 1.000 rs6137962 chr20:23443966 T/C cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1385374 0.920 rs11059910 chr12:129271719 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.63 7.7 0.38 1.52e-13 Systemic lupus erythematosus; LIHC cis rs6547741 1.000 rs6706610 chr2:27778091 G/A cg27432699 chr2:27873401 GPN1 0.72 11.62 0.53 1.6e-26 Oral cavity cancer; LIHC cis rs2251381 0.741 rs2735966 chr21:30538174 G/A cg08807101 chr21:30365312 RNF160 0.76 10.18 0.48 1.97e-21 Selective IgA deficiency; LIHC cis rs11719291 0.915 rs11557629 chr3:48732223 G/A cg07636037 chr3:49044803 WDR6 -0.69 -7.18 -0.36 4.28e-12 Cognitive function; LIHC cis rs7188697 0.922 rs173475 chr16:58580530 T/C cg02549819 chr16:58548995 SETD6 -0.46 -7.34 -0.37 1.54e-12 QT interval; LIHC cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg02290350 chr8:58132656 NA 0.51 10.97 0.51 3.29e-24 Developmental language disorder (linguistic errors); LIHC cis rs7551222 0.749 rs6594018 chr1:204568152 A/G cg20240347 chr1:204465584 NA -0.31 -6.29 -0.32 9.9e-10 Schizophrenia; LIHC cis rs6840360 0.530 rs6839802 chr4:152485834 G/A cg22705602 chr4:152727874 NA -0.33 -6.49 -0.33 2.93e-10 Intelligence (multi-trait analysis); LIHC cis rs875971 0.660 rs3764903 chr7:66098482 G/A cg14393609 chr7:65229607 NA -0.37 -5.8 -0.3 1.53e-8 Aortic root size; LIHC cis rs904251 0.766 rs1757175 chr6:37486694 T/C cg01843034 chr6:37503916 NA -0.47 -7.36 -0.37 1.39e-12 Cognitive performance; LIHC cis rs12477438 0.539 rs13394175 chr2:99590713 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.54 -8.47 -0.42 7.15e-16 Chronic sinus infection; LIHC cis rs1552244 0.882 rs56224841 chr3:10044014 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs868036 0.609 rs2045960 chr15:68092079 G/A cg24579218 chr15:68104479 NA -0.34 -5.83 -0.3 1.29e-8 Restless legs syndrome; LIHC cis rs3096299 0.685 rs4785571 chr16:89565169 A/G cg08392591 chr16:89556376 ANKRD11 0.39 6.4 0.33 5.21e-10 Multiple myeloma (IgH translocation); LIHC trans rs7618501 0.521 rs3774759 chr3:49939120 G/T cg21659725 chr3:3221576 CRBN 0.57 8.19 0.4 5.34e-15 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.868 rs2531342 chr5:140130612 C/T cg19875535 chr5:140030758 IK -0.35 -5.75 -0.3 1.94e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs12701220 0.817 rs1058729 chr7:1087283 C/T cg00990874 chr7:1149470 C7orf50 -0.63 -8.94 -0.44 2.57e-17 Bronchopulmonary dysplasia; LIHC cis rs6450176 1.000 rs12521454 chr5:53297304 T/C ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs853679 0.517 rs9468298 chr6:28122345 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs9457247 0.730 rs9459841 chr6:167431949 G/A cg07741184 chr6:167504864 NA 0.32 7.48 0.37 6.41e-13 Crohn's disease; LIHC cis rs2576037 0.583 rs11660085 chr18:44529603 A/G cg19077165 chr18:44547161 KATNAL2 0.46 6.85 0.35 3.37e-11 Personality dimensions; LIHC trans rs561341 1.000 rs4795669 chr17:30244701 C/T cg20587970 chr11:113659929 NA -0.74 -8.29 -0.41 2.64e-15 Hip circumference adjusted for BMI; LIHC cis rs9733 0.519 rs3768005 chr1:150680988 A/T cg17724175 chr1:150552817 MCL1 0.49 9.89 0.47 1.92e-20 Tonsillectomy; LIHC cis rs2242116 1.000 rs2242116 chr3:46941116 A/G cg23352942 chr3:46931381 PTH1R -0.28 -7.06 -0.36 9.36e-12 Birth weight; LIHC cis rs7131987 0.903 rs11050161 chr12:29420049 A/G cg14222432 chr12:29376421 FAR2 0.38 7.31 0.37 1.89e-12 QT interval; LIHC cis rs2836974 0.604 rs2854727 chr21:40713787 A/G cg11644478 chr21:40555479 PSMG1 0.43 6.11 0.31 2.72e-9 Cognitive function; LIHC cis rs7589728 0.563 rs12479338 chr2:88444513 C/T cg14558114 chr2:88469736 THNSL2 0.59 5.71 0.3 2.39e-8 Plasma clusterin levels; LIHC cis rs769267 0.965 rs4808200 chr19:19554803 C/T cg03709012 chr19:19516395 GATAD2A 0.98 17.58 0.69 9.77e-50 Tonsillectomy; LIHC cis rs743757 1.000 rs2236979 chr3:50486895 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.51 7.95 0.4 2.66e-14 Diastolic blood pressure; LIHC cis rs11644362 0.903 rs2014726 chr16:12992849 T/C cg06890432 chr16:12997467 SHISA9 -0.39 -6.59 -0.34 1.64e-10 Positive affect;Subjective well-being; LIHC cis rs61008539 0.586 rs6959154 chr7:856320 C/T cg24004478 chr7:855632 UNC84A 0.47 7.45 0.37 7.75e-13 Perceived unattractiveness to mosquitoes; LIHC cis rs7582180 0.629 rs13004216 chr2:100945402 G/A cg14675211 chr2:100938903 LONRF2 0.53 8.44 0.42 8.97e-16 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.882 rs3732967 chr3:10015437 T/C cg13047869 chr3:10149882 C3orf24 0.43 5.94 0.31 7.03e-9 Alzheimer's disease; LIHC cis rs66887589 0.592 rs11731571 chr4:120221185 G/A cg09307838 chr4:120376055 NA 0.56 8.35 0.41 1.77e-15 Diastolic blood pressure; LIHC cis rs61990749 0.511 rs10130790 chr14:78324192 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.49 7.81 0.39 7.05e-14 Fibroblast growth factor basic levels; LIHC cis rs12701220 0.655 rs7778968 chr7:1144622 C/G cg04025307 chr7:1156635 C7orf50 0.51 6.73 0.34 7.3e-11 Bronchopulmonary dysplasia; LIHC cis rs1865760 0.929 rs12195653 chr6:25958621 A/G cg15691649 chr6:25882328 NA -0.37 -5.71 -0.3 2.42e-8 Height; LIHC cis rs2153535 0.601 rs6906170 chr6:8543128 T/A cg23788917 chr6:8435910 SLC35B3 0.61 8.51 0.42 5.35e-16 Motion sickness; LIHC cis rs2412488 0.893 rs57297394 chr4:54359130 G/A cg22241045 chr4:54363911 LNX1 0.46 7.66 0.38 1.93e-13 DNA methylation (variation); LIHC cis rs2204008 0.627 rs11176531 chr12:38152166 T/G cg26384229 chr12:38710491 ALG10B 0.8 9.57 0.46 2.24e-19 Bladder cancer; LIHC cis rs2153535 0.580 rs1319169 chr6:8464456 G/A cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs8062405 0.723 rs12445744 chr16:28588395 A/C cg07451762 chr16:28383216 NA 0.38 6.76 0.34 6.11e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs77861329 1.000 rs55834589 chr3:52081724 C/T cg08692210 chr3:52188851 WDR51A 0.78 6.7 0.34 8.78e-11 Macrophage inflammatory protein 1b levels; LIHC cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg17691542 chr6:26056736 HIST1H1C 0.4 5.93 0.31 7.61e-9 Height; LIHC cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg07424592 chr7:64974309 NA 0.76 8.63 0.42 2.3e-16 Diabetic kidney disease; LIHC cis rs780096 0.545 rs6716894 chr2:27583273 A/G cg22903471 chr2:27725779 GCKR -0.54 -9.38 -0.45 9.68e-19 Total body bone mineral density; LIHC cis rs1395 0.710 rs72817533 chr2:27482612 A/G cg23587288 chr2:27483067 SLC30A3 -0.35 -6.44 -0.33 3.99e-10 Blood metabolite levels; LIHC cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg13271783 chr10:134563150 INPP5A -0.59 -7.17 -0.36 4.73e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7408868 0.908 rs62113794 chr19:15277337 C/A cg14696996 chr19:15285081 NOTCH3 0.54 7.09 0.36 7.55e-12 Pulse pressure; LIHC cis rs1552244 0.572 rs6442154 chr3:10168785 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.79 8.21 0.41 4.49e-15 Alzheimer's disease; LIHC cis rs4665809 1.000 rs750451 chr2:26324241 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.72 -8.97 -0.44 1.93e-17 Gut microbiome composition (summer); LIHC cis rs1707322 1.000 rs2458400 chr1:46530798 C/T cg03146154 chr1:46216737 IPP -0.44 -7.05 -0.36 9.75e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2839186 0.500 rs13052701 chr21:47660045 A/T cg12379764 chr21:47803548 PCNT -0.64 -8.81 -0.43 6.5e-17 Testicular germ cell tumor; LIHC cis rs67311347 1.000 rs7612015 chr3:40399974 A/C cg24209194 chr3:40518798 ZNF619 0.42 5.97 0.31 6.06e-9 Renal cell carcinoma; LIHC cis rs17401966 0.838 rs17034643 chr1:10332102 A/G cg19773385 chr1:10388646 KIF1B 0.41 7.41 0.37 9.89e-13 Hepatocellular carcinoma; LIHC cis rs4654899 0.929 rs7552999 chr1:21314454 T/C cg08539965 chr1:21396338 EIF4G3 0.34 5.93 0.31 7.44e-9 Superior frontal gyrus grey matter volume; LIHC cis rs898097 0.805 rs60233158 chr17:80896612 A/G cg15664640 chr17:80829946 TBCD 0.68 10.8 0.5 1.4e-23 Breast cancer; LIHC cis rs11628318 0.853 rs6575925 chr14:103034507 C/T cg12046867 chr14:103022105 NA -0.55 -8.27 -0.41 3.1e-15 Platelet count; LIHC cis rs9503598 0.502 rs1077845 chr6:3433201 G/T cg00476032 chr6:3446245 SLC22A23 -0.32 -5.87 -0.3 1.03e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs2073499 0.810 rs78501918 chr3:50369914 A/G cg03645007 chr3:50255295 SLC38A3 0.51 6.04 0.31 3.98e-9 Schizophrenia; LIHC cis rs240764 0.658 rs9377214 chr6:101212146 G/A cg09795085 chr6:101329169 ASCC3 -0.41 -5.73 -0.3 2.25e-8 Neuroticism; LIHC cis rs6060717 0.529 rs6060535 chr20:34235522 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.5 -5.89 -0.3 9.45e-9 Hip circumference adjusted for BMI; LIHC cis rs9326248 1.000 rs7107152 chr11:117056080 C/T cg26566898 chr11:117069891 TAGLN -0.48 -7.45 -0.37 7.58e-13 Blood protein levels; LIHC cis rs10791097 0.694 rs10894273 chr11:130742155 G/T cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs754466 0.651 rs10824582 chr10:79603688 T/C cg17075019 chr10:79541650 NA -0.75 -11.43 -0.53 7.57e-26 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs11971779 0.680 rs6961812 chr7:139043808 A/C cg07862535 chr7:139043722 LUC7L2 0.59 10.23 0.48 1.3e-21 Diisocyanate-induced asthma; LIHC cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg00800038 chr16:89945340 TCF25 -0.65 -10.32 -0.49 6.62e-22 Skin colour saturation; LIHC cis rs7264396 0.666 rs1536147 chr20:34173046 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.5 8.45 0.42 8.2e-16 Total cholesterol levels; LIHC cis rs11711311 1.000 rs9809850 chr3:113429010 C/T cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.11 0.44 6.91e-18 IgG glycosylation; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg10777881 chr1:144044138 NA 0.43 6.1 0.31 2.94e-9 Hepatitis; LIHC cis rs2404602 0.692 rs2137307 chr15:77149020 T/A cg23625390 chr15:77176239 SCAPER 0.35 5.8 0.3 1.49e-8 Blood metabolite levels; LIHC cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg16497277 chr3:49208875 KLHDC8B -0.51 -6.39 -0.33 5.43e-10 Menarche (age at onset); LIHC cis rs2404602 0.669 rs12916324 chr15:77179603 G/A cg03037974 chr15:76606532 NA 0.73 14.33 0.61 8.54e-37 Blood metabolite levels; LIHC cis rs921968 0.643 rs535830 chr2:219372233 C/G cg02985541 chr2:219472218 PLCD4 0.46 8.73 0.43 1.18e-16 Mean corpuscular hemoglobin concentration; LIHC cis rs1865760 0.786 rs1436308 chr6:25939567 T/G cg12310025 chr6:25882481 NA -0.42 -6.34 -0.32 7.27e-10 Height; LIHC cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg11645453 chr3:52864694 ITIH4 0.22 6.0 0.31 4.95e-9 Bipolar disorder; LIHC trans rs1814175 0.817 rs10769648 chr11:50013992 T/C cg18944383 chr4:111397179 ENPEP 0.27 7.03 0.36 1.16e-11 Height; LIHC cis rs3812831 0.695 rs7995986 chr13:114938802 A/G cg06611532 chr13:114900021 NA 0.42 7.71 0.38 1.38e-13 Schizophrenia; LIHC cis rs8078723 0.802 rs9303283 chr17:38192633 A/G cg17467752 chr17:38218738 THRA 0.83 16.28 0.66 1.54e-44 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs4759375 1.000 rs7315453 chr12:123825389 T/C cg00376283 chr12:123451042 ABCB9 0.5 6.37 0.33 6.18e-10 HDL cholesterol; LIHC cis rs644799 0.965 rs2508713 chr11:95547927 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.7 10.14 0.48 2.71e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs8027181 0.839 rs2277598 chr15:73027478 T/C cg25996835 chr15:72978165 BBS4;HIGD2B 0.5 7.72 0.39 1.26e-13 Triglyceride levels; LIHC cis rs903552 1.000 rs12915569 chr15:102001883 G/A cg25677261 chr15:102009856 PCSK6 -0.44 -5.9 -0.3 8.57e-9 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg12463550 chr7:65579703 CRCP 0.71 7.49 0.38 5.99e-13 Diabetic kidney disease; LIHC cis rs1395 0.744 rs11126931 chr2:27474306 C/T cg23587288 chr2:27483067 SLC30A3 -0.34 -6.43 -0.33 4.37e-10 Blood metabolite levels; LIHC cis rs8072100 0.544 rs9284377 chr17:45386412 C/T cg08085267 chr17:45401833 C17orf57 -0.41 -5.93 -0.31 7.5e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg08219700 chr8:58056026 NA 0.46 5.8 0.3 1.48e-8 Developmental language disorder (linguistic errors); LIHC cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg19318889 chr4:1322082 MAEA 0.54 8.54 0.42 4.48e-16 Longevity; LIHC cis rs11098499 0.874 rs13123591 chr4:120105990 T/G cg09307838 chr4:120376055 NA 0.52 7.74 0.39 1.16e-13 Corneal astigmatism; LIHC cis rs8062405 0.723 rs62031562 chr16:28609329 A/T cg07451762 chr16:28383216 NA 0.41 7.09 0.36 7.54e-12 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22333016 chr4:54244258 FIP1L1 -0.4 -6.14 -0.32 2.24e-9 Pancreatic cancer; LIHC cis rs1555322 0.530 rs932562 chr20:33871310 T/C cg17927777 chr20:33865990 NA 0.56 6.56 0.33 2.01e-10 Attention deficit hyperactivity disorder; LIHC cis rs8060686 0.545 rs3826164 chr16:68280317 A/G cg09835421 chr16:68378352 PRMT7 0.52 6.05 0.31 3.85e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg11764359 chr7:65958608 NA 0.59 6.14 0.32 2.32e-9 Diabetic kidney disease; LIHC cis rs2108225 0.872 rs2051954 chr7:107441097 G/C cg18560240 chr7:107437656 SLC26A3 -0.5 -7.66 -0.38 1.93e-13 Ulcerative colitis; LIHC cis rs7833986 0.501 rs72653953 chr8:56970795 C/T cg23139584 chr8:56987506 RPS20;SNORD54 0.84 8.62 0.42 2.6e-16 Height; LIHC cis rs7116495 0.609 rs6592457 chr11:71738086 G/C cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.06e-17 Severe influenza A (H1N1) infection; LIHC cis rs6430585 0.646 rs1057031 chr2:136633962 G/A cg07169764 chr2:136633963 MCM6 1.36 24.52 0.8 2.38e-77 Corneal structure; LIHC cis rs7980687 0.628 rs1609520 chr12:123735937 A/G cg05973401 chr12:123451056 ABCB9 -0.41 -5.83 -0.3 1.28e-8 Height;Educational attainment;Head circumference (infant); LIHC cis rs9560113 1.000 rs9555812 chr13:112181535 A/G cg14154082 chr13:112174009 NA 0.3 6.26 0.32 1.16e-9 Menarche (age at onset); LIHC cis rs2012796 0.785 rs61986599 chr14:81860917 G/A cg23690444 chr14:81902736 NA -0.5 -6.86 -0.35 3.17e-11 Night sleep phenotypes; LIHC cis rs7224737 0.789 rs8071235 chr17:40300126 C/A cg00647820 chr17:40259828 DHX58 -0.29 -5.96 -0.31 6.39e-9 Fibrinogen levels; LIHC cis rs9910055 0.530 rs2269908 chr17:42294198 G/C cg09913183 chr17:42254507 C17orf65;ASB16 0.64 9.4 0.45 7.82e-19 Total body bone mineral density; LIHC cis rs6429082 0.875 rs4659524 chr1:235583354 C/T cg26050004 chr1:235667680 B3GALNT2 -0.43 -6.59 -0.34 1.66e-10 Adiposity; LIHC cis rs9527 0.637 rs7096169 chr10:104618695 A/G cg11784071 chr10:104629166 AS3MT -0.36 -5.81 -0.3 1.4e-8 Arsenic metabolism; LIHC cis rs950776 0.518 rs4243083 chr15:78833830 C/G cg06917634 chr15:78832804 PSMA4 -0.91 -13.98 -0.6 1.84e-35 Sudden cardiac arrest; LIHC cis rs4808199 0.895 rs2285628 chr19:19467996 T/A cg20644253 chr19:19431407 KIAA0892;SF4 0.56 7.9 0.39 3.93e-14 Nonalcoholic fatty liver disease; LIHC cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg02782426 chr3:40428986 ENTPD3 -0.35 -6.48 -0.33 3.18e-10 Renal cell carcinoma; LIHC cis rs722599 0.748 rs61978932 chr14:75342954 C/T cg11812906 chr14:75593930 NEK9 -0.45 -7.0 -0.35 1.33e-11 IgG glycosylation; LIHC cis rs16958440 1.000 rs60422392 chr18:44621473 T/C cg17192377 chr18:44677553 HDHD2 0.61 6.89 0.35 2.72e-11 Sitting height ratio; LIHC trans rs916888 0.610 rs199436 chr17:44789285 C/T cg22968622 chr17:43663579 NA -0.47 -6.82 -0.35 4.19e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4319547 0.698 rs10773178 chr12:122944752 T/C cg23029597 chr12:123009494 RSRC2 -0.44 -6.3 -0.32 8.94e-10 Body mass index; LIHC cis rs763121 0.853 rs5757203 chr22:39044152 G/C cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg05590025 chr7:65112418 INTS4L2 -0.62 -6.79 -0.34 4.9e-11 Diabetic kidney disease; LIHC cis rs704795 0.902 rs11887784 chr2:27679919 A/G cg21747090 chr2:27597821 SNX17 -0.39 -5.73 -0.3 2.22e-8 Menopause (age at onset); LIHC trans rs7613875 0.620 rs13079006 chr3:49996924 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.42 6.38 0.33 5.86e-10 Body mass index; LIHC cis rs11030122 0.702 rs12286710 chr11:3967171 T/G cg18678763 chr11:4115507 RRM1 -0.56 -8.39 -0.41 1.26e-15 Mean platelet volume;Platelet distribution width; LIHC cis rs9858542 0.953 rs9853683 chr3:49512588 A/G cg02487422 chr3:49467188 NICN1 -0.42 -5.77 -0.3 1.79e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs933688 1.000 rs11950530 chr5:90688740 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.9 16.44 0.66 3.67e-45 Smoking behavior; LIHC cis rs2242420 0.920 rs16825746 chr1:21958909 G/A cg18150885 chr1:21978612 RAP1GAP -0.47 -5.81 -0.3 1.47e-8 Hematological and biochemical traits; LIHC cis rs4819052 1.000 rs9306123 chr21:46709922 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.76 10.4 0.49 3.46e-22 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9309473 1.000 rs7564890 chr2:73641853 T/C cg20560298 chr2:73613845 ALMS1 -0.57 -6.73 -0.34 7.3e-11 Metabolite levels; LIHC cis rs6684514 0.961 rs10908497 chr1:156274740 G/A cg16558208 chr1:156270281 VHLL 0.54 10.28 0.49 8.88e-22 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; LIHC cis rs709400 0.663 rs62007719 chr14:103943130 G/T cg26031613 chr14:104095156 KLC1 0.75 9.45 0.46 5.41e-19 Body mass index; LIHC cis rs9916302 0.904 rs34363096 chr17:37594294 G/A cg00129232 chr17:37814104 STARD3 -0.4 -6.43 -0.33 4.4e-10 Glomerular filtration rate (creatinine); LIHC cis rs9902453 0.765 rs3102562 chr17:28040403 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 13.4 0.59 3.43e-33 Coffee consumption (cups per day); LIHC cis rs1005277 0.579 rs2505237 chr10:38438898 T/G cg03665457 chr10:38645376 HSD17B7P2 -0.41 -5.97 -0.31 6.04e-9 Extrinsic epigenetic age acceleration; LIHC cis rs2066819 1.000 rs116849218 chr12:56683975 C/T cg26714650 chr12:56694279 CS -1.4 -13.79 -0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs780096 0.546 rs2293572 chr2:27728777 C/G cg21747090 chr2:27597821 SNX17 0.4 5.9 0.3 8.59e-9 Total body bone mineral density; LIHC cis rs6502050 0.835 rs35131307 chr17:80128439 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.96 -0.31 6.44e-9 Life satisfaction; LIHC cis rs3806843 0.966 rs1030166 chr5:140185473 G/A cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs2576037 1.000 rs2576037 chr18:44585420 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.47 -7.02 -0.35 1.2e-11 Personality dimensions; LIHC cis rs12644436 0.628 rs9991506 chr4:88782111 G/A cg06891869 chr4:88767617 MEPE 0.43 7.55 0.38 3.94e-13 HIV-1 viral setpoint; LIHC cis rs16828019 0.852 rs11209576 chr1:41586029 T/C cg03962019 chr1:41807865 NA 0.5 7.22 0.36 3.33e-12 Intelligence (multi-trait analysis); LIHC cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg24642844 chr7:1081250 C7orf50 -0.95 -9.36 -0.45 1.09e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4819052 0.851 rs2838840 chr21:46668494 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.52 7.44 0.37 8.22e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs35306767 0.761 rs11253540 chr10:1011958 C/T cg26597838 chr10:835615 NA -0.94 -8.99 -0.44 1.73e-17 Eosinophil percentage of granulocytes; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg06558623 chr16:89946397 TCF25 0.85 13.1 0.58 4.51e-32 Skin colour saturation; LIHC cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.18 0.52 6.17e-25 Colorectal cancer; LIHC cis rs11098699 0.821 rs11935129 chr4:124207106 T/A cg09941581 chr4:124220074 SPATA5 0.33 6.52 0.33 2.56e-10 Mosquito bite size; LIHC cis rs6570726 0.905 rs452770 chr6:145847162 T/C cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs7615952 0.733 rs13314847 chr3:125644788 C/T cg07211511 chr3:129823064 LOC729375 -0.85 -10.5 -0.49 1.57e-22 Blood pressure (smoking interaction); LIHC cis rs6754311 0.509 rs12616520 chr2:136516748 A/T cg15123519 chr2:136567270 LCT 0.39 7.34 0.37 1.56e-12 Mosquito bite size; LIHC cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg08280861 chr8:58055591 NA 0.51 6.04 0.31 4.06e-9 Developmental language disorder (linguistic errors); LIHC cis rs8060686 0.641 rs1074143 chr16:68127278 A/G cg05110241 chr16:68378359 PRMT7 -0.6 -6.77 -0.34 5.6e-11 HDL cholesterol;Metabolic syndrome; LIHC trans rs8073060 0.586 rs225291 chr17:33927126 A/G cg19694781 chr19:47549865 TMEM160 -0.63 -7.83 -0.39 6.21e-14 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7772486 0.875 rs9373483 chr6:146364194 A/G cg23711669 chr6:146136114 FBXO30 0.6 10.67 0.5 3.87e-23 Lobe attachment (rater-scored or self-reported); LIHC cis rs7208859 0.614 rs73265646 chr17:29244023 C/T cg13385521 chr17:29058706 SUZ12P 0.79 7.79 0.39 7.99e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1494373 0.543 rs61830219 chr1:220847364 G/A cg06786860 chr1:220876396 NA -0.43 -6.4 -0.33 5.16e-10 Response to antipsychotic therapy (extrapyramidal side effects); LIHC cis rs35110281 0.627 rs1436291 chr21:44965485 T/C cg04455712 chr21:45112962 RRP1B 0.39 6.54 0.33 2.22e-10 Mean corpuscular volume; LIHC cis rs35110281 0.807 rs28840140 chr21:45039163 T/C cg01579765 chr21:45077557 HSF2BP -0.32 -6.1 -0.31 2.81e-9 Mean corpuscular volume; LIHC cis rs2731664 0.792 rs335435 chr5:176867943 A/G cg23176889 chr5:176863531 GRK6 -0.71 -12.37 -0.56 2.72e-29 Intelligence (multi-trait analysis); LIHC cis rs8067354 0.958 rs8081468 chr17:57836924 A/G cg02344993 chr17:57696989 CLTC 0.54 8.55 0.42 4.26e-16 Hemoglobin concentration; LIHC cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg06873352 chr17:61820015 STRADA 0.5 7.48 0.37 6.31e-13 Height; LIHC cis rs4665809 0.652 rs6727974 chr2:26524639 A/G cg27170947 chr2:26402098 FAM59B 0.54 7.19 0.36 4.14e-12 Gut microbiome composition (summer); LIHC cis rs5769765 1.000 rs4824112 chr22:50284345 A/G cg02269571 chr22:50332266 NA -0.72 -9.54 -0.46 2.7e-19 Schizophrenia; LIHC cis rs798766 0.779 rs3134866 chr4:1723265 A/G cg21231739 chr4:1642635 FAM53A -0.36 -5.76 -0.3 1.86e-8 Bladder cancer;Urinary bladder cancer; LIHC cis rs60871478 0.786 rs55899111 chr7:827843 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.51 -5.91 -0.3 8.5e-9 Cerebrospinal P-tau181p levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg15558129 chr1:219347279 LYPLAL1 0.46 6.39 0.33 5.47e-10 Lung function (FEV1/FVC); LIHC cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.81 -0.3 1.4e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04498032 chr1:155242826 CLK2 0.44 6.66 0.34 1.08e-10 Pancreatic cancer; LIHC cis rs826838 1.000 rs860400 chr12:39081279 A/G cg26384229 chr12:38710491 ALG10B -0.61 -9.1 -0.44 7.86e-18 Heart rate; LIHC cis rs950776 0.593 rs680244 chr15:78871288 T/C cg06917634 chr15:78832804 PSMA4 -0.63 -8.58 -0.42 3.37e-16 Sudden cardiac arrest; LIHC cis rs9534288 0.699 rs2146886 chr13:46646711 C/T cg15192986 chr13:46630673 CPB2 -0.42 -6.2 -0.32 1.65e-9 Blood protein levels; LIHC cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg21280719 chr6:42927975 GNMT -0.27 -6.03 -0.31 4.3e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs35110281 0.666 rs2838348 chr21:45107285 C/G cg04455712 chr21:45112962 RRP1B -0.51 -8.63 -0.42 2.41e-16 Mean corpuscular volume; LIHC cis rs2997447 0.739 rs3008224 chr1:26389647 G/A cg19633962 chr1:26362018 EXTL1 -0.58 -6.53 -0.33 2.43e-10 QRS complex (12-leadsum); LIHC cis rs875971 0.862 rs2420174 chr7:65645361 C/T cg11764359 chr7:65958608 NA -0.84 -14.15 -0.61 4.2500000000000003e-36 Aortic root size; LIHC cis rs8084351 0.518 rs11660990 chr18:50763049 T/C cg24270629 chr18:50823537 DCC -0.51 -7.58 -0.38 3.29e-13 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs2842992 0.915 rs2842958 chr6:160108425 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.7 12.12 0.55 2.27e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs2303745 0.544 rs6512180 chr19:17399153 C/T cg02221750 chr19:17393354 ANKLE1 -0.41 -5.77 -0.3 1.82e-8 Systemic lupus erythematosus; LIHC trans rs875971 0.577 rs35072105 chr7:65609817 A/G cg26939375 chr7:64535504 NA -0.46 -7.02 -0.35 1.24e-11 Aortic root size; LIHC cis rs921968 0.541 rs532425 chr2:219434194 A/G cg02176678 chr2:219576539 TTLL4 0.53 7.42 0.37 9.37e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs8017423 0.967 rs4904658 chr14:90721640 C/T cg04374321 chr14:90722782 PSMC1 0.77 15.19 0.63 3.32e-40 Mortality in heart failure; LIHC cis rs765787 0.530 rs11634794 chr15:45534492 A/C cg26924012 chr15:45694286 SPATA5L1 -0.37 -5.76 -0.3 1.86e-8 Uric acid levels; LIHC cis rs10751667 0.961 rs7482484 chr11:927020 C/T ch.11.42038R chr11:967971 AP2A2 0.57 10.48 0.49 1.74e-22 Alzheimer's disease (late onset); LIHC cis rs1568889 1.000 rs7949057 chr11:28255053 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.49 6.88 0.35 2.86e-11 Bipolar disorder; LIHC cis rs9640161 0.750 rs1983440 chr7:150023941 G/C cg10018233 chr7:150070692 REPIN1 0.57 9.68 0.46 9.89e-20 Blood protein levels;Circulating chemerin levels; LIHC cis rs1538970 0.962 rs3219472 chr1:45804050 A/G cg24296786 chr1:45957014 TESK2 0.52 7.35 0.37 1.43e-12 Platelet count; LIHC cis rs1348850 0.507 rs10186934 chr2:178425998 T/C cg27490568 chr2:178487706 NA 0.93 9.04 0.44 1.23e-17 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs6582630 0.537 rs7299661 chr12:38527713 C/T cg13010199 chr12:38710504 ALG10B 0.42 5.78 0.3 1.67e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs67460515 0.563 rs11717272 chr3:160810355 A/G cg17135325 chr3:160939158 NMD3 0.54 7.62 0.38 2.58e-13 Parkinson's disease; LIHC cis rs8062405 0.698 rs7188071 chr16:28917644 T/C cg07451762 chr16:28383216 NA -0.33 -6.06 -0.31 3.6e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.56 -7.77 -0.39 9.43e-14 Lymphocyte counts; LIHC cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg23205692 chr1:25664452 TMEM50A 0.39 6.22 0.32 1.45e-9 Plateletcrit;Mean corpuscular volume; LIHC cis rs7312774 0.618 rs57361179 chr12:107337483 T/C cg16260113 chr12:107380972 MTERFD3 0.85 11.15 0.52 8.03e-25 Severe influenza A (H1N1) infection; LIHC cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg02990361 chr1:107599529 PRMT6 -0.66 -10.94 -0.51 4.5e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs2280018 0.963 rs4985147 chr16:15168760 T/C cg27102117 chr16:15229624 NA 0.28 6.0 0.31 5.1e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7512552 0.839 rs834229 chr1:150384665 G/C cg15654264 chr1:150340011 RPRD2 0.69 11.23 0.52 4.02e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg11060661 chr22:24314208 DDT;DDTL -0.54 -8.68 -0.42 1.64e-16 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs1005277 0.579 rs2505257 chr10:38372664 A/G cg27523141 chr10:43048294 ZNF37B 0.35 6.08 0.31 3.16e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4788570 0.537 rs56222754 chr16:71491806 G/A cg06353428 chr16:71660113 MARVELD3 -1.11 -9.99 -0.48 8.56e-21 Intelligence (multi-trait analysis); LIHC cis rs6664467 1 rs6664467 chr1:151738403 G/A cg07092448 chr1:151763213 TDRKH -0.73 -7.29 -0.37 2.13e-12 Carotid plaque burden; LIHC cis rs35883536 0.967 rs1984134 chr1:101109307 A/G cg14515779 chr1:101123966 NA -0.66 -13.17 -0.58 2.6e-32 Monocyte count; LIHC cis rs155076 1.000 rs484365 chr13:21845944 G/T cg14456004 chr13:21872349 NA -1.17 -12.65 -0.56 2.3e-30 White matter hyperintensity burden; LIHC cis rs6570726 0.935 rs387965 chr6:145869366 A/G cg23711669 chr6:146136114 FBXO30 0.52 8.79 0.43 7.62e-17 Lobe attachment (rater-scored or self-reported); LIHC cis rs1256061 0.603 rs1256036 chr14:64743332 C/T cg23250157 chr14:64679961 SYNE2 0.4 5.92 0.3 8.02e-9 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg26338869 chr17:61819248 STRADA 0.59 8.68 0.42 1.69e-16 Prudent dietary pattern; LIHC cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg05665937 chr4:1216051 CTBP1 0.39 6.02 0.31 4.55e-9 Obesity-related traits; LIHC cis rs473651 0.935 rs508483 chr2:239339709 T/C cg18131467 chr2:239335373 ASB1 1.06 19.67 0.73 3.84e-58 Multiple system atrophy; LIHC cis rs8062405 0.789 rs1968751 chr16:28631759 T/C cg00204512 chr16:28754710 NA -0.38 -6.3 -0.32 9.25e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9921222 1.000 rs9921222 chr16:375782 A/G cg12437481 chr16:420112 MRPL28 0.55 7.67 0.38 1.76e-13 Bone mineral density (spine);Bone mineral density; LIHC trans rs9929218 0.954 rs7199991 chr16:68818245 T/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.61 -8.68 -0.42 1.59e-16 Colorectal cancer; LIHC cis rs7027203 1.000 rs7854820 chr9:96526027 A/G cg14598338 chr9:96623480 NA 0.32 6.14 0.32 2.28e-9 DNA methylation (variation); LIHC cis rs7246657 0.943 rs10415358 chr19:37808863 C/A cg23950597 chr19:37808831 NA -0.55 -7.11 -0.36 6.89e-12 Coronary artery calcification; LIHC cis rs10504229 0.679 rs72649107 chr8:58030453 C/A cg02290350 chr8:58132656 NA 0.31 7.17 0.36 4.59e-12 Developmental language disorder (linguistic errors); LIHC cis rs4803468 1.000 rs2231940 chr19:41944237 T/C cg14132834 chr19:41945861 ATP5SL 0.45 6.61 0.34 1.5e-10 Height; LIHC cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg09455208 chr3:40491958 NA 0.39 7.9 0.39 3.81e-14 Renal cell carcinoma; LIHC trans rs983392 0.709 rs2015475 chr11:59998963 A/C cg17275991 chr19:58003312 ZNF419 0.43 6.13 0.31 2.45e-9 Alzheimer's disease (late onset); LIHC cis rs10464366 0.544 rs9639812 chr7:39192058 C/T cg10621924 chr7:39171070 POU6F2 0.41 6.38 0.33 5.76e-10 IgG glycosylation; LIHC cis rs5769765 0.862 rs138856 chr22:50199378 G/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.67 -8.01 -0.4 1.76e-14 Schizophrenia; LIHC cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs11792861 0.926 rs1333344 chr9:111776224 C/T cg05043794 chr9:111880884 C9orf5 -0.3 -6.9 -0.35 2.58e-11 Menarche (age at onset); LIHC cis rs807669 0.777 rs9605972 chr22:19253274 C/T cg02655711 chr22:19163373 SLC25A1 0.38 7.23 0.36 3.19e-12 Metabolite levels; LIHC cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.58 0.34 1.79e-10 Bipolar disorder; LIHC cis rs2836950 0.565 rs2150413 chr21:40614878 C/T cg17971929 chr21:40555470 PSMG1 -0.39 -5.88 -0.3 9.94e-9 Menarche (age at onset); LIHC cis rs11255291 0.668 rs6602265 chr10:7732939 A/G cg00997801 chr10:7671259 ITIH5 0.37 6.03 0.31 4.22e-9 Ovarian reserve; LIHC cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg06453172 chr10:134556979 INPP5A -0.63 -8.03 -0.4 1.54e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs7980687 0.527 rs28533432 chr12:123873242 C/T cg00376283 chr12:123451042 ABCB9 0.6 9.74 0.47 5.97e-20 Height;Educational attainment;Head circumference (infant); LIHC cis rs6088590 0.735 rs2273684 chr20:33529766 G/T cg24642439 chr20:33292090 TP53INP2 -0.48 -6.6 -0.34 1.58e-10 Coronary artery disease; LIHC cis rs6960043 0.652 rs6461149 chr7:15044103 C/T cg19272540 chr7:15055459 NA 0.25 6.71 0.34 7.94e-11 Type 2 diabetes; LIHC cis rs826838 0.967 rs980572 chr12:39127673 A/C cg26384229 chr12:38710491 ALG10B 0.61 8.86 0.43 4.33e-17 Heart rate; LIHC cis rs13040088 1.000 rs2273412 chr20:61553802 G/A cg23096297 chr20:61557774 DIDO1 0.83 11.17 0.52 6.84e-25 Menopause (age at onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg23104955 chr8:74205400 RPL7 -0.49 -6.31 -0.32 8.76e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs1801251 0.929 rs10933409 chr2:233629386 A/G cg08000102 chr2:233561755 GIGYF2 0.76 11.49 0.53 4.57e-26 Coronary artery disease; LIHC cis rs933688 1.000 rs2367526 chr5:90740525 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.35 0.72 6.94e-57 Smoking behavior; LIHC cis rs651907 0.557 rs11917569 chr3:101355063 G/C cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -6.0 -0.31 5.11e-9 Colorectal cancer; LIHC cis rs2204008 0.652 rs11513964 chr12:37998214 C/G cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs4407350 0.870 rs4823327 chr22:44908708 T/C cg26276947 chr22:44892394 LDOC1L 0.35 6.79 0.34 4.89e-11 Intelligence (multi-trait analysis); LIHC cis rs7605378 0.528 rs7592587 chr2:200786516 C/G cg23649088 chr2:200775458 C2orf69 0.55 8.04 0.4 1.53e-14 Osteoporosis; LIHC cis rs739401 0.611 rs3782069 chr11:3033275 G/A cg25174290 chr11:3078921 CARS 0.61 9.19 0.45 3.87e-18 Longevity; LIHC trans rs459571 0.883 rs2520096 chr9:136919416 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.54 -8.29 -0.41 2.6e-15 Platelet distribution width; LIHC cis rs1348850 0.519 rs1527406 chr2:178525655 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.61 8.04 0.4 1.53e-14 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7927592 0.763 rs2513277 chr11:68360887 T/G cg20283391 chr11:68216788 NA -0.38 -6.08 -0.31 3.14e-9 Total body bone mineral density; LIHC cis rs372883 0.613 rs1153289 chr21:30686212 G/T cg24692254 chr21:30365293 RNF160 -0.51 -6.39 -0.33 5.39e-10 Pancreatic cancer; LIHC cis rs9543976 1.000 rs4885324 chr13:76173747 G/A cg01531495 chr13:76123901 UCHL3 0.49 5.81 0.3 1.4e-8 Diabetic retinopathy; LIHC cis rs2228479 0.850 rs17226428 chr16:89842884 T/A cg19635926 chr16:89946313 TCF25 0.52 6.54 0.33 2.24e-10 Skin colour saturation; LIHC cis rs7582180 0.629 rs13010911 chr2:100953390 G/C cg14675211 chr2:100938903 LONRF2 0.54 8.51 0.42 5.58e-16 Intelligence (multi-trait analysis); LIHC cis rs11671005 0.693 rs34023391 chr19:58913368 G/A cg25952890 chr19:58913133 NA 0.7 7.19 0.36 4.02e-12 Mean platelet volume; LIHC cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 11.63 0.53 1.49e-26 Alzheimer's disease; LIHC cis rs2444240 0.902 rs626225 chr11:120034115 G/A cg04390734 chr11:120039366 NA 0.32 6.14 0.32 2.3e-9 Corneal curvature; LIHC cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg06697600 chr4:7070879 GRPEL1 -0.65 -10.31 -0.49 7.01e-22 Monocyte percentage of white cells; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg01401336 chr17:2606734 KIAA0664 0.42 6.48 0.33 3.27e-10 Longevity; LIHC cis rs933688 1.000 rs61612071 chr5:90741470 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.35 0.72 6.94e-57 Smoking behavior; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg04305134 chr10:75173374 ANXA7 -0.42 -6.76 -0.34 6.08e-11 Body mass index; LIHC trans rs10411161 1.000 rs10411161 chr19:52372976 C/T cg22319618 chr22:45562946 NUP50 -0.56 -7.51 -0.38 5.07e-13 Breast cancer; LIHC cis rs7091068 0.671 rs1223296 chr10:95404621 T/C cg20715218 chr10:95462985 C10orf4 -0.61 -6.66 -0.34 1.1e-10 Urinary tract infection frequency; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg18474185 chr14:105817333 PACS2 0.45 6.96 0.35 1.75e-11 Longevity; LIHC cis rs763014 0.932 rs2269560 chr16:682442 A/C cg09263875 chr16:632152 PIGQ 0.59 10.36 0.49 4.87e-22 Height; LIHC cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg08280861 chr8:58055591 NA 0.52 6.28 0.32 1.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs6952808 0.692 rs12666575 chr7:2004421 C/T cg04565464 chr8:145669602 NFKBIL2 0.43 7.19 0.36 4.15e-12 Bipolar disorder and schizophrenia; LIHC cis rs6840360 0.550 rs62327267 chr4:152518753 G/T cg22705602 chr4:152727874 NA -0.31 -6.2 -0.32 1.63e-9 Intelligence (multi-trait analysis); LIHC cis rs2257205 0.588 rs7209327 chr17:56741834 A/G cg05425664 chr17:57184151 TRIM37 -0.59 -6.47 -0.33 3.49e-10 Pancreatic cancer; LIHC cis rs713477 0.654 rs4901569 chr14:55912880 C/T cg13175173 chr14:55914753 NA -0.3 -6.77 -0.34 5.54e-11 Pediatric bone mineral content (femoral neck); LIHC cis rs7165170 0.549 rs10852133 chr15:91098715 C/T cg26821196 chr15:91095069 CRTC3 0.39 7.1 0.36 7.1e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10911251 0.508 rs6424890 chr1:183112764 A/G ch.1.3577855R chr1:183094577 LAMC1 0.61 10.67 0.5 3.82e-23 Colorectal cancer; LIHC cis rs7618501 0.966 rs2352974 chr3:49890613 C/T cg24110177 chr3:50126178 RBM5 -0.39 -6.03 -0.31 4.33e-9 Intelligence (multi-trait analysis); LIHC cis rs11122272 0.735 rs2491404 chr1:231512127 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.29e-23 Hemoglobin concentration; LIHC cis rs992157 0.835 rs34353396 chr2:219153982 T/C cg00012203 chr2:219082015 ARPC2 -0.83 -13.24 -0.58 1.39e-32 Colorectal cancer; LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg18306943 chr3:40428807 ENTPD3 0.42 7.38 0.37 1.21e-12 Renal cell carcinoma; LIHC cis rs12477438 0.765 rs12612688 chr2:99613091 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -7.6 -0.38 2.84e-13 Chronic sinus infection; LIHC cis rs9814567 1.000 rs2056603 chr3:134312749 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -11.91 -0.54 1.31e-27 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs801193 0.844 rs2244022 chr7:66202430 A/G cg18876405 chr7:65276391 NA 0.39 6.87 0.35 3.13e-11 Aortic root size; LIHC cis rs7772486 0.790 rs3923579 chr6:146230232 C/G cg23711669 chr6:146136114 FBXO30 -0.71 -12.36 -0.56 2.98e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs9942416 0.660 rs166183 chr5:74977845 T/C cg19683494 chr5:74908142 NA -0.58 -7.57 -0.38 3.52e-13 Age-related disease endophenotypes; LIHC cis rs151997 0.925 rs26087 chr5:50172911 G/A cg06027927 chr5:50259733 NA 0.57 7.56 0.38 3.69e-13 Callous-unemotional behaviour; LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.63 12.42 0.56 1.66e-29 Prudent dietary pattern; LIHC cis rs244293 0.965 rs244350 chr17:53196132 C/G cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.3 0.37 2.07e-12 Menarche (age at onset); LIHC cis rs2404602 0.647 rs1443115 chr15:77041829 T/C cg23625390 chr15:77176239 SCAPER -0.54 -8.98 -0.44 1.81e-17 Blood metabolite levels; LIHC cis rs875971 1.000 rs7792762 chr7:66004138 T/C cg11764359 chr7:65958608 NA 0.85 15.4 0.64 5.25e-41 Aortic root size; LIHC cis rs10426930 0.816 rs2009654 chr19:5061345 A/T cg18473234 chr19:5097819 KDM4B -0.52 -6.82 -0.35 4.05e-11 Monocyte percentage of white cells; LIHC cis rs3806843 0.932 rs2563269 chr5:140136468 G/T cg19875535 chr5:140030758 IK -0.37 -6.09 -0.31 3.11e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs4332037 0.950 rs62442895 chr7:1936938 G/A cg23422044 chr7:1970798 MAD1L1 -0.64 -7.26 -0.37 2.57e-12 Bipolar disorder; LIHC cis rs7666738 0.830 rs28818218 chr4:98880575 A/C cg05340658 chr4:99064831 C4orf37 0.67 12.33 0.55 3.73e-29 Colonoscopy-negative controls vs population controls; LIHC trans rs2739330 0.760 rs1002286 chr22:24257337 A/G cg06437703 chr8:37914619 EIF4EBP1 0.61 9.47 0.46 4.83e-19 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg18663498 chr6:27487068 NA 0.43 6.35 0.32 7.04e-10 Pancreatic cancer; LIHC cis rs748404 0.697 rs471122 chr15:43558574 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.43 -6.54 -0.33 2.29e-10 Lung cancer; LIHC cis rs2230307 0.536 rs580678 chr1:100483009 C/A cg24955406 chr1:100503596 HIAT1 0.62 6.15 0.32 2.14e-9 Carotid intima media thickness; LIHC cis rs589448 0.902 rs2603089 chr12:69776800 C/T cg14784868 chr12:69753453 YEATS4 -0.97 -22.41 -0.77 4.31e-69 Cerebrospinal fluid biomarker levels; LIHC cis rs4233366 0.585 rs3924264 chr1:161178684 C/T cg13853198 chr1:161185092 FCER1G -0.33 -8.26 -0.41 3.26e-15 Asthma; LIHC cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg18230493 chr5:56204884 C5orf35 -0.47 -6.55 -0.33 2.08e-10 Initial pursuit acceleration; LIHC cis rs7786877 0.723 rs6969584 chr7:100209747 A/C cg00334542 chr7:100209784 MOSPD3 -0.73 -7.55 -0.38 3.89e-13 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg12311346 chr5:56204834 C5orf35 -0.57 -7.54 -0.38 4.41e-13 Initial pursuit acceleration; LIHC cis rs7552404 0.727 rs4949677 chr1:76266662 T/A cg03433033 chr1:76189801 ACADM 0.57 7.15 0.36 5.29e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs5758511 0.680 rs5758698 chr22:42684818 C/T cg00645731 chr22:42541494 CYP2D7P1 0.49 7.38 0.37 1.18e-12 Birth weight; LIHC cis rs2522056 1.000 rs2405528 chr5:131794298 G/A cg24060327 chr5:131705240 SLC22A5 0.53 7.0 0.35 1.38e-11 Lymphocyte counts;Fibrinogen; LIHC cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg19318889 chr4:1322082 MAEA 0.63 9.97 0.47 9.91e-21 Longevity; LIHC cis rs80282103 0.618 rs11816485 chr10:1147974 T/C cg08668510 chr10:1095578 IDI1 0.62 6.07 0.31 3.45e-9 Glomerular filtration rate (creatinine); LIHC cis rs2569991 0.588 rs14191 chr3:12940346 G/A cg22481960 chr3:13008800 IQSEC1 -0.42 -7.23 -0.36 3.2e-12 Periodontitis (DPAL); LIHC cis rs12701220 0.655 rs6955290 chr7:1151066 A/G cg00990874 chr7:1149470 C7orf50 0.7 10.09 0.48 3.93e-21 Bronchopulmonary dysplasia; LIHC cis rs4319547 0.956 rs7316149 chr12:123063912 G/A cg05707623 chr12:122985044 ZCCHC8 -0.61 -8.1 -0.4 1e-14 Body mass index; LIHC cis rs61160187 0.503 rs755077 chr5:60000608 C/T cg02684056 chr5:59996105 DEPDC1B 0.4 5.89 0.3 9.26e-9 Educational attainment (years of education);Educational attainment (college completion); LIHC cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg08645402 chr16:4508243 NA 0.44 8.3 0.41 2.43e-15 Schizophrenia; LIHC cis rs507080 0.845 rs510408 chr11:118558901 G/C cg04173919 chr11:118528438 PHLDB1 0.35 6.56 0.33 2.01e-10 Serum metabolite levels; LIHC cis rs1577917 0.958 rs12198876 chr6:86525476 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -11.04 -0.51 1.95e-24 Response to antipsychotic treatment; LIHC cis rs798554 0.836 rs798526 chr7:2775542 G/C cg19346786 chr7:2764209 NA -0.46 -6.99 -0.35 1.43e-11 Height; LIHC cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg11890956 chr21:40555474 PSMG1 1.05 15.27 0.64 1.74e-40 Cognitive function; LIHC cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg09455208 chr3:40491958 NA 0.42 8.46 0.42 7.64e-16 Renal cell carcinoma; LIHC cis rs10197940 0.510 rs7557092 chr2:152423459 T/A cg06191203 chr2:152266755 RIF1 -0.43 -7.14 -0.36 5.73e-12 Lung cancer; LIHC cis rs1707322 0.752 rs10430105 chr1:46138876 G/A cg06784218 chr1:46089804 CCDC17 0.41 7.57 0.38 3.45e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11123170 0.640 rs1015754 chr2:113967990 T/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.47 -5.9 -0.3 8.85e-9 Renal function-related traits (BUN); LIHC cis rs11608355 0.515 rs12822282 chr12:109923207 G/A cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs6963495 0.818 rs6956234 chr7:105149707 A/G cg19920283 chr7:105172520 RINT1 0.68 6.42 0.33 4.44e-10 Bipolar disorder (body mass index interaction); LIHC cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg11494091 chr17:61959527 GH2 0.48 8.6 0.42 2.98e-16 Prudent dietary pattern; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06391107 chr19:40502439 ZNF546 0.44 6.37 0.33 6.14e-10 Pancreatic cancer; LIHC cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.79 6.23 0.32 1.39e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs9399135 0.967 rs6569990 chr6:135365818 C/T cg24558204 chr6:135376177 HBS1L 0.42 6.81 0.35 4.49e-11 Red blood cell count; LIHC cis rs6782228 0.606 rs6775270 chr3:128403498 A/G cg16766828 chr3:128327626 NA -0.39 -6.2 -0.32 1.63e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs7613875 0.600 rs2856238 chr3:50158191 C/T cg24110177 chr3:50126178 RBM5 -0.56 -9.02 -0.44 1.41e-17 Body mass index; LIHC cis rs1113500 0.933 rs10785833 chr1:108639082 A/G cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.91e-12 Growth-regulated protein alpha levels; LIHC cis rs1801251 0.896 rs79793315 chr2:233690864 C/T cg08000102 chr2:233561755 GIGYF2 -0.75 -11.02 -0.51 2.28e-24 Coronary artery disease; LIHC cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.82 8.08 0.4 1.1e-14 Platelet count; LIHC cis rs7107174 1.000 rs10899483 chr11:78061057 G/C cg02023728 chr11:77925099 USP35 0.42 8.1 0.4 9.7e-15 Testicular germ cell tumor; LIHC cis rs12586317 0.547 rs2383693 chr14:35500205 A/C cg16230307 chr14:35515116 FAM177A1 0.8 13.4 0.59 3.43e-33 Psoriasis; LIHC cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC cis rs7542091 0.704 rs7550330 chr1:210044587 G/A cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.08e-9 Monobrow; LIHC cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg11644478 chr21:40555479 PSMG1 0.84 10.57 0.5 8.49e-23 Cognitive function; LIHC cis rs7408868 1.000 rs2074617 chr19:15276055 C/G cg02272795 chr19:15279244 NOTCH3 -0.32 -5.78 -0.3 1.68e-8 Pulse pressure; LIHC cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg22800045 chr5:56110881 MAP3K1 -0.51 -5.94 -0.31 7.12e-9 Initial pursuit acceleration; LIHC cis rs7020830 0.830 rs17487601 chr9:37213641 G/A cg14294708 chr9:37120828 ZCCHC7 1.16 24.98 0.8 4.17e-79 Schizophrenia; LIHC cis rs3796619 1.000 rs12647929 chr4:1092019 G/T cg27284194 chr4:1044797 NA 0.63 10.58 0.5 8.3e-23 Recombination rate (males); LIHC cis rs1348850 0.914 rs1348849 chr2:178358072 C/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.89 14.31 0.61 9.85e-37 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs8067354 0.574 rs2531899 chr17:58007193 A/G cg13753209 chr17:57696993 CLTC -0.72 -10.81 -0.5 1.22e-23 Hemoglobin concentration; LIHC cis rs1008375 1.000 rs4698634 chr4:17630192 A/C cg16339924 chr4:17578868 LAP3 -0.44 -6.31 -0.32 8.85e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg03452623 chr4:187889614 NA -0.33 -8.18 -0.4 5.64e-15 Lobe attachment (rater-scored or self-reported); LIHC cis rs17125944 0.505 rs17125762 chr14:53289288 A/G cg00686598 chr14:53173677 PSMC6 1.24 13.94 0.6 2.72e-35 Alzheimer's disease (late onset); LIHC cis rs2380220 0.808 rs72922390 chr6:95934317 G/A cg15832292 chr6:96025679 MANEA -0.6 -6.73 -0.34 7.25e-11 Behavioural disinhibition (generation interaction); LIHC cis rs9457247 0.663 rs2301436 chr6:167437988 C/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.69 -0.43 1.51e-16 Crohn's disease; LIHC cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 9.32e-15 Prudent dietary pattern; LIHC cis rs2286503 0.752 rs6461669 chr7:22858066 T/G cg11367502 chr7:22862612 TOMM7 0.49 8.62 0.42 2.45e-16 Fibrinogen; LIHC cis rs116095464 0.558 rs10475136 chr5:232796 A/G cg22496380 chr5:211416 CCDC127 -1.02 -10.51 -0.49 1.47e-22 Breast cancer; LIHC cis rs778371 0.647 rs974321 chr2:233638351 G/A cg08000102 chr2:233561755 GIGYF2 0.78 9.57 0.46 2.25e-19 Schizophrenia; LIHC cis rs986417 1.000 rs10151958 chr14:60977275 T/C cg27398547 chr14:60952738 C14orf39 0.84 9.71 0.46 7.63e-20 Gut microbiota (bacterial taxa); LIHC cis rs12701220 0.553 rs9639882 chr7:1133731 G/A cg26769984 chr7:1090371 C7orf50 0.46 5.71 0.3 2.39e-8 Bronchopulmonary dysplasia; LIHC cis rs7534824 0.625 rs17409499 chr1:101504936 C/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 7.31 0.37 1.87e-12 Refractive astigmatism; LIHC cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg24209194 chr3:40518798 ZNF619 0.44 6.28 0.32 1.05e-9 Renal cell carcinoma; LIHC cis rs9640161 0.742 rs2159236 chr7:150017214 A/G cg17279839 chr7:150038598 RARRES2 0.51 10.76 0.5 1.84e-23 Blood protein levels;Circulating chemerin levels; LIHC cis rs7520050 0.902 rs9429088 chr1:46497500 T/A cg03146154 chr1:46216737 IPP -0.37 -5.99 -0.31 5.36e-9 Red blood cell count;Reticulocyte count; LIHC cis rs738322 0.934 rs84473 chr22:38557326 T/C cg25457927 chr22:38595422 NA -0.27 -6.58 -0.34 1.78e-10 Cutaneous nevi; LIHC cis rs769267 0.930 rs3794993 chr19:19611550 G/T cg15052019 chr19:19431593 KIAA0892;SF4 0.44 6.27 0.32 1.09e-9 Tonsillectomy; LIHC cis rs9549367 0.789 rs12584008 chr13:113881228 C/T cg18105134 chr13:113819100 PROZ -0.67 -11.66 -0.53 1.09e-26 Platelet distribution width; LIHC cis rs11190604 1.000 rs11190556 chr10:102209223 G/A cg07080220 chr10:102295463 HIF1AN 0.5 6.92 0.35 2.24e-11 Palmitoleic acid (16:1n-7) levels; LIHC cis rs7582720 1.000 rs72934710 chr2:203709776 C/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.75 6.03 0.31 4.27e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.21 -0.32 1.5e-9 Total body bone mineral density; LIHC cis rs10493773 0.775 rs11161662 chr1:86185040 A/G cg17807903 chr1:86174739 ZNHIT6 -0.55 -10.05 -0.48 5.22e-21 Urate levels in overweight individuals; LIHC cis rs9649213 0.574 rs12873 chr7:97922773 T/C cg08684580 chr7:98029266 BAIAP2L1 -0.38 -5.95 -0.31 6.55e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs7561273 0.586 rs6545264 chr2:24310105 A/G cg06627628 chr2:24431161 ITSN2 -0.43 -5.79 -0.3 1.56e-8 Quantitative traits; LIHC cis rs2933343 0.700 rs1680778 chr3:128614185 A/C cg24203234 chr3:128598194 ACAD9 0.45 6.27 0.32 1.07e-9 IgG glycosylation; LIHC cis rs7267979 0.509 rs6115218 chr20:25566485 A/G cg13962466 chr20:25176127 ENTPD6 0.49 6.67 0.34 1e-10 Liver enzyme levels (alkaline phosphatase); LIHC cis rs12478296 0.681 rs73007114 chr2:242984903 T/C cg06360820 chr2:242988706 NA -0.97 -12.44 -0.56 1.42e-29 Obesity-related traits; LIHC cis rs963731 0.522 rs6755527 chr2:39187190 T/C cg04010122 chr2:39346883 SOS1 -0.76 -5.84 -0.3 1.2e-8 Corticobasal degeneration; LIHC cis rs2732480 0.500 rs12828309 chr12:48641160 C/T cg21466736 chr12:48725269 NA -0.71 -10.9 -0.51 6.18e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7959452 0.535 rs7133487 chr12:69774377 G/A cg22834771 chr12:69754056 YEATS4 -0.52 -9.27 -0.45 2.09e-18 Blood protein levels; LIHC cis rs9816226 0.590 rs872602 chr3:185826028 A/G cg00760338 chr3:185826511 ETV5 0.98 15.36 0.64 7.51e-41 Obesity;Body mass index; LIHC cis rs10540 1.000 rs71487292 chr11:486076 G/A cg03352830 chr11:487213 PTDSS2 0.78 6.19 0.32 1.76e-9 Body mass index; LIHC cis rs11098499 0.863 rs17050695 chr4:120489527 G/T cg09307838 chr4:120376055 NA 0.68 10.63 0.5 5.22e-23 Corneal astigmatism; LIHC cis rs933688 1.000 rs7720132 chr5:90745105 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.35 0.72 6.94e-57 Smoking behavior; LIHC cis rs11583043 1.000 rs12750667 chr1:101498682 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 5.96 0.31 6.44e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13724827 chr9:126030353 STRBP 0.49 6.82 0.35 4.23e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs7635838 0.596 rs13353463 chr3:11260221 T/C cg00170343 chr3:11313890 ATG7 0.53 8.22 0.41 4.22e-15 HDL cholesterol; LIHC cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg13047869 chr3:10149882 C3orf24 0.48 5.96 0.31 6.31e-9 Alzheimer's disease; LIHC cis rs4555082 0.874 rs2142190 chr14:105719306 G/A cg13114125 chr14:105738426 BRF1 -0.79 -10.09 -0.48 4e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs11122272 0.705 rs2808599 chr1:231533482 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.71 -0.5 2.94e-23 Hemoglobin concentration; LIHC cis rs2637030 0.559 rs256116 chr5:52962251 C/T cg06476337 chr5:52856530 NDUFS4 0.43 6.8 0.35 4.68e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs2274273 0.713 rs56725788 chr14:55540101 A/G cg01864836 chr14:55583639 NA -0.38 -6.52 -0.33 2.49e-10 Protein biomarker; LIHC cis rs56104184 0.775 rs55756106 chr19:49403055 A/G cg21252483 chr19:49399788 TULP2 -1.06 -12.19 -0.55 1.27e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7503807 0.967 rs12939549 chr17:78611724 C/T cg09596252 chr17:78655493 RPTOR -0.38 -6.81 -0.35 4.4e-11 Obesity; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg19006130 chr11:118478252 PHLDB1 0.44 6.43 0.33 4.32e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg05350360 chr19:4475274 HDGF2 -0.37 -6.3 -0.32 9.04e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs801193 1.000 rs13239306 chr7:66136017 T/G cg14393609 chr7:65229607 NA -0.37 -5.76 -0.3 1.86e-8 Aortic root size; LIHC cis rs2439831 0.867 rs2412780 chr15:43655794 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.77 11.31 0.52 2.11e-25 Lung cancer in ever smokers; LIHC cis rs9783347 1.000 rs4150566 chr11:18355599 C/G cg15585147 chr11:18324498 HPS5 0.42 6.67 0.34 1.04e-10 Pancreatic cancer; LIHC cis rs1003719 0.788 rs2835595 chr21:38466203 G/T cg10648535 chr21:38446584 PIGP;TTC3 0.77 11.95 0.54 9.62e-28 Eye color traits; LIHC cis rs2075371 0.966 rs1646646 chr7:133996905 G/T cg11752832 chr7:134001865 SLC35B4 0.51 7.59 0.38 3.04e-13 Mean platelet volume; LIHC cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg10210624 chr19:58662595 ZNF329 0.73 7.33 0.37 1.65e-12 Cholesterol, total; LIHC cis rs8064024 0.538 rs12446456 chr16:4922201 C/T cg08329684 chr16:4932620 PPL 0.37 6.75 0.34 6.16e-11 Cancer; LIHC cis rs2832191 0.636 rs8131283 chr21:30516796 A/G cg24692254 chr21:30365293 RNF160 -0.43 -6.71 -0.34 7.91e-11 Dental caries; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg22022001 chr13:99096806 FARP1 0.45 6.35 0.32 7e-10 Longevity; LIHC cis rs1580019 0.523 rs9791770 chr7:32582252 C/A cg06627557 chr7:32535165 LSM5;AVL9 1.12 24.8 0.8 2.06e-78 Cognitive ability; LIHC cis rs870825 0.616 rs12498890 chr4:185636096 C/G cg04058563 chr4:185651563 MLF1IP -0.59 -6.52 -0.33 2.46e-10 Blood protein levels; LIHC trans rs4650994 0.544 rs4075631 chr1:178506594 C/A cg05059571 chr16:84539110 KIAA1609 -0.42 -7.03 -0.36 1.16e-11 HDL cholesterol levels;HDL cholesterol; LIHC cis rs11711311 0.824 rs9876528 chr3:113357196 G/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.54 -0.33 2.24e-10 IgG glycosylation; LIHC cis rs7937682 0.889 rs479667 chr11:111484034 C/T cg09085632 chr11:111637200 PPP2R1B -0.92 -11.06 -0.51 1.66e-24 Primary sclerosing cholangitis; LIHC cis rs6973256 0.605 rs7794168 chr7:133357606 T/C cg03336402 chr7:133662267 EXOC4 -0.37 -5.72 -0.3 2.36e-8 Intelligence (multi-trait analysis); LIHC cis rs10464366 0.544 rs6952466 chr7:39155032 A/T cg18850127 chr7:39170497 POU6F2 0.46 8.33 0.41 2.04e-15 IgG glycosylation; LIHC cis rs919433 0.679 rs6719832 chr2:198533369 C/T cg03934865 chr2:198174659 NA -0.46 -6.86 -0.35 3.33e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs75064307 0.834 rs4855560 chr3:108116129 G/C cg03329597 chr3:108125523 MYH15 0.5 6.63 0.34 1.32e-10 Intelligence (multi-trait analysis); LIHC cis rs739401 0.595 rs402806 chr11:3066432 A/G cg08508325 chr11:3079039 CARS -0.35 -7.47 -0.37 6.64e-13 Longevity; LIHC cis rs10779751 0.770 rs1148480 chr1:11172006 A/G cg08854313 chr1:11322531 MTOR 0.81 13.77 0.6 1.22e-34 Body mass index; LIHC trans rs7615952 0.609 rs13088451 chr3:125553499 G/C cg07211511 chr3:129823064 LOC729375 -0.52 -7.85 -0.39 5.24e-14 Blood pressure (smoking interaction); LIHC cis rs8077889 0.956 rs4792910 chr17:41840229 T/C cg26893861 chr17:41843967 DUSP3 1.03 11.41 0.53 9.08e-26 Triglycerides; LIHC cis rs7100689 0.646 rs1538815 chr10:82137670 A/G cg00277334 chr10:82204260 NA -0.59 -7.35 -0.37 1.43e-12 Post bronchodilator FEV1; LIHC cis rs7818382 0.967 rs7812465 chr8:96050557 C/T cg16049864 chr8:95962084 TP53INP1 0.54 10.61 0.5 6.39e-23 Alzheimer's disease (late onset); LIHC cis rs6977660 0.619 rs12530799 chr7:19782793 G/A cg07541023 chr7:19748670 TWISTNB 0.39 5.79 0.3 1.59e-8 Thyroid stimulating hormone; LIHC cis rs12479064 0.694 rs4341989 chr2:100046783 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.45 -6.26 -0.32 1.17e-9 Chronic sinus infection; LIHC cis rs2576037 0.562 rs477826 chr18:44397649 A/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.41 -5.89 -0.3 9.41e-9 Personality dimensions; LIHC cis rs74233809 1.000 rs74233296 chr10:104655350 T/C cg03493300 chr10:104813866 CNNM2 0.44 5.8 0.3 1.49e-8 Birth weight; LIHC cis rs1371867 1.000 rs1371867 chr8:101330209 A/C cg06636551 chr8:101224915 SPAG1 -0.45 -8.24 -0.41 3.74e-15 Atrioventricular conduction; LIHC cis rs28595532 0.546 rs36058627 chr4:119233201 G/T cg21605333 chr4:119757512 SEC24D 0.8 6.82 0.35 4.23e-11 Cannabis dependence symptom count; LIHC cis rs7542091 0.669 rs11119357 chr1:210042382 C/T cg23283495 chr1:209979779 IRF6 0.35 5.97 0.31 6.09e-9 Monobrow; LIHC cis rs4006360 0.540 rs9915780 chr17:39301074 T/C cg20663846 chr17:39254439 KRTAP4-8 0.2 5.8 0.3 1.48e-8 Bipolar disorder and schizophrenia; LIHC trans rs6938574 0.672 rs6569520 chr6:128365034 C/G cg12121162 chr6:144904561 UTRN 0.54 6.07 0.31 3.38e-9 Menarche (age at onset); LIHC cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg22800045 chr5:56110881 MAP3K1 0.69 8.82 0.43 5.95e-17 Initial pursuit acceleration; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg12260146 chr3:33840237 PDCD6IP 0.49 6.36 0.33 6.6e-10 Lung function (FEV1/FVC); LIHC cis rs6565180 0.926 rs12446288 chr16:30388709 A/G cg17640201 chr16:30407289 ZNF48 0.81 14.07 0.61 8.29e-36 Tonsillectomy; LIHC cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg17158414 chr2:27665306 KRTCAP3 -0.44 -6.04 -0.31 3.94e-9 Total body bone mineral density; LIHC cis rs10857712 0.754 rs2297033 chr10:135234848 C/T cg17796960 chr10:135278976 LOC619207 -0.35 -5.74 -0.3 2.13e-8 Systemic lupus erythematosus; LIHC cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -11.78 -0.54 4.1e-27 Alzheimer's disease; LIHC cis rs2708977 1.000 rs10184209 chr2:97337491 G/T cg01950434 chr2:97203154 ARID5A 0.49 7.14 0.36 5.8e-12 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs6782228 0.606 rs6787559 chr3:128381086 T/C cg16766828 chr3:128327626 NA -0.4 -6.39 -0.33 5.54e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs875971 0.545 rs4718325 chr7:65680310 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.36 7.2 0.36 3.79e-12 Aortic root size; LIHC cis rs311392 0.902 rs423150 chr8:55092804 C/T cg11783602 chr8:55087084 NA -0.31 -6.23 -0.32 1.36e-9 Pelvic organ prolapse (moderate/severe); LIHC cis rs780096 0.526 rs3845686 chr2:27655447 T/G cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.78 -0.3 1.72e-8 Total body bone mineral density; LIHC cis rs6570726 0.818 rs9399555 chr6:145877554 T/C cg05347473 chr6:146136440 FBXO30 0.36 5.93 0.31 7.32e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6701037 0.566 rs4344281 chr1:175135376 C/T cg00321850 chr1:175162397 KIAA0040 0.47 7.63 0.38 2.28e-13 Alcohol dependence; LIHC cis rs400736 0.860 rs371452 chr1:8084051 C/T cg25007680 chr1:8021821 PARK7 0.59 9.57 0.46 2.19e-19 Response to antidepressants and depression; LIHC cis rs9457247 0.663 rs9459845 chr6:167440501 C/G cg07741184 chr6:167504864 NA 0.26 6.17 0.32 1.95e-9 Crohn's disease; LIHC cis rs7772486 0.686 rs1045820 chr6:145947080 C/T cg23711669 chr6:146136114 FBXO30 0.64 11.63 0.53 1.44e-26 Lobe attachment (rater-scored or self-reported); LIHC cis rs9916302 0.904 rs2338798 chr17:37547269 T/C cg03013999 chr17:37608204 MED1 -0.35 -5.92 -0.31 7.63e-9 Glomerular filtration rate (creatinine); LIHC cis rs6964587 1.000 rs3753109 chr7:91630001 G/C cg17063962 chr7:91808500 NA 1.01 19.3 0.72 1.12e-56 Breast cancer; LIHC cis rs2580764 0.565 rs35631428 chr2:55244438 G/A cg09592903 chr2:55203963 RTN4 -0.68 -12.29 -0.55 5.31e-29 Mean platelet volume; LIHC cis rs11960470 0.669 rs55873624 chr5:50325671 A/G cg06027927 chr5:50259733 NA 0.6 8.26 0.41 3.15e-15 Breast cancer; LIHC cis rs651907 0.557 rs11712748 chr3:101383562 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.7 11.74 0.54 5.46e-27 Colorectal cancer; LIHC cis rs2625529 0.824 rs4777471 chr15:72207804 A/G cg16672083 chr15:72433130 SENP8 -0.31 -5.8 -0.3 1.48e-8 Red blood cell count; LIHC cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg16434002 chr17:42200994 HDAC5 -0.53 -7.67 -0.38 1.78e-13 Total body bone mineral density; LIHC cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg06481639 chr22:41940642 POLR3H 0.71 7.18 0.36 4.41e-12 Vitiligo; LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg12064134 chr16:90016061 DEF8 -0.44 -5.75 -0.3 1.93e-8 Skin colour saturation; LIHC cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.22e-8 Menopause (age at onset); LIHC cis rs611744 0.870 rs429884 chr8:109115122 T/C cg21045802 chr8:109455806 TTC35 0.5 8.48 0.42 7e-16 Dupuytren's disease; LIHC cis rs2933343 0.729 rs1683780 chr3:128640239 C/T cg25356066 chr3:128598488 ACAD9 0.52 7.14 0.36 5.64e-12 IgG glycosylation; LIHC cis rs7208859 0.573 rs56031503 chr17:29075665 T/C cg13385521 chr17:29058706 SUZ12P 0.82 8.21 0.41 4.61e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.68 11.22 0.52 4.52e-25 Menarche (age at onset); LIHC cis rs3824867 0.804 rs12419342 chr11:47468545 C/T cg20307385 chr11:47447363 PSMC3 0.59 7.9 0.39 3.95e-14 Mean corpuscular hemoglobin; LIHC trans rs10038113 0.530 rs57095562 chr5:26025857 T/A cg05807885 chr1:204183355 GOLT1A 0.31 6.2 0.32 1.62e-9 Autism; LIHC cis rs8014671 0.553 rs2877661 chr14:70916559 G/T cg25576086 chr14:70833871 SYNJ2BP -0.45 -7.06 -0.36 9.34e-12 Prostate cancer; LIHC cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC trans rs4332037 0.506 rs62442924 chr7:1989976 C/T cg11693508 chr17:37793320 STARD3 0.79 7.95 0.39 2.7e-14 Bipolar disorder; LIHC cis rs16958440 0.867 rs12386076 chr18:44673340 T/C cg17192377 chr18:44677553 HDHD2 0.62 6.68 0.34 9.88e-11 Sitting height ratio; LIHC cis rs9372253 0.678 rs9487392 chr6:110708626 C/T cg00083206 chr6:110721305 DDO 0.33 6.5 0.33 2.89e-10 Platelet distribution width; LIHC cis rs35110281 0.712 rs162345 chr21:44954155 T/G cg21573476 chr21:45109991 RRP1B -0.51 -9.59 -0.46 1.92e-19 Mean corpuscular volume; LIHC cis rs7116495 0.609 rs2155142 chr11:71642524 A/G cg10381502 chr11:71823885 C11orf51 0.83 7.56 0.38 3.62e-13 Severe influenza A (H1N1) infection; LIHC trans rs13113518 0.812 rs13140590 chr4:56414833 A/G cg15358633 chr12:38710606 ALG10B 0.44 6.3 0.32 9.14e-10 Height; LIHC cis rs3924048 0.574 rs11121931 chr1:12617009 G/A cg00291366 chr1:12616550 NA 0.43 8.92 0.43 2.79e-17 Optic cup area; LIHC cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg16405210 chr4:1374714 KIAA1530 -0.9 -14.5 -0.62 1.79e-37 Longevity; LIHC cis rs7312774 0.881 rs12320167 chr12:107310167 G/A cg16260113 chr12:107380972 MTERFD3 0.78 10.19 0.48 1.8e-21 Severe influenza A (H1N1) infection; LIHC cis rs7666738 0.830 rs10025174 chr4:98914172 A/G cg05340658 chr4:99064831 C4orf37 0.64 11.65 0.53 1.25e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs7044106 0.500 rs56725168 chr9:123492576 T/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.78 13.16 0.58 2.84e-32 Hip circumference adjusted for BMI; LIHC cis rs9814567 0.752 rs6764764 chr3:134331167 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.59 9.49 0.46 3.95e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2153535 0.601 rs1855765 chr6:8444325 C/T cg07606381 chr6:8435919 SLC35B3 0.79 11.64 0.53 1.29e-26 Motion sickness; LIHC cis rs6088580 0.634 rs6059860 chr20:33063830 A/C cg08999081 chr20:33150536 PIGU 0.67 13.33 0.58 6.18e-33 Glomerular filtration rate (creatinine); LIHC cis rs4237845 0.537 rs12426201 chr12:58259752 C/T cg04478727 chr12:58166393 METTL1;FAM119B 0.59 8.17 0.4 6.18e-15 Intelligence (multi-trait analysis); LIHC cis rs7703744 0.672 rs6864305 chr5:118683065 T/C cg04195774 chr5:118677172 TNFAIP8 -0.4 -5.77 -0.3 1.77e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs3008870 1.000 rs12117131 chr1:67451922 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.47 -0.67 2.69e-45 Lymphocyte percentage of white cells; LIHC cis rs12497850 0.897 rs6446252 chr3:48911125 C/T cg07636037 chr3:49044803 WDR6 0.93 16.74 0.67 2.27e-46 Parkinson's disease; LIHC cis rs7044106 0.791 rs10984994 chr9:123478769 A/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.53 -8.13 -0.4 7.98e-15 Hip circumference adjusted for BMI; LIHC cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg05564831 chr3:52568323 NT5DC2 0.35 5.72 0.3 2.35e-8 Intelligence (multi-trait analysis); LIHC cis rs2108225 0.658 rs1476673 chr7:107435945 C/G cg18560240 chr7:107437656 SLC26A3 -0.5 -7.81 -0.39 7.2e-14 Ulcerative colitis; LIHC cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg26338869 chr17:61819248 STRADA 0.53 7.18 0.36 4.33e-12 Height; LIHC cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.05 0.31 3.76e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg04193083 chr17:41323562 NBR1 -0.47 -7.33 -0.37 1.72e-12 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs861020 0.771 rs629150 chr1:209998467 C/T cg09163369 chr1:210001066 C1orf107 0.48 5.94 0.31 6.99e-9 Orofacial clefts; LIHC trans rs6598955 0.671 rs11247900 chr1:26612460 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.75 -8.73 -0.43 1.14e-16 Obesity-related traits; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg02106306 chr15:31620290 KLF13 0.62 8.08 0.4 1.15e-14 Hepatitis; LIHC cis rs1577917 0.518 rs2475787 chr6:86415236 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.34 6.25 0.32 1.24e-9 Response to antipsychotic treatment; LIHC cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg03517284 chr6:25882590 NA -0.67 -8.22 -0.41 4.21e-15 Intelligence (multi-trait analysis); LIHC cis rs1997103 1.000 rs4947503 chr7:55409427 G/T cg17469321 chr7:55412551 NA 0.48 7.1 0.36 7.32e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs796364 0.806 rs76112266 chr2:201087157 C/G cg25936922 chr2:200820526 C2orf60;C2orf47 -0.66 -7.21 -0.36 3.55e-12 Schizophrenia; LIHC cis rs1185460 0.967 rs11217137 chr11:118931030 A/G cg23280166 chr11:118938394 VPS11 0.55 7.23 0.36 3.19e-12 Coronary artery disease; LIHC cis rs12478296 0.681 rs6598999 chr2:242994405 C/A cg18898632 chr2:242989856 NA -0.5 -7.25 -0.36 2.82e-12 Obesity-related traits; LIHC cis rs7249142 0.597 rs759999 chr19:19281207 A/C cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.43 -7.03 -0.36 1.15e-11 IgG glycosylation; LIHC cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg06238570 chr21:40685208 BRWD1 0.59 7.07 0.36 8.98e-12 Cognitive function; LIHC cis rs6089829 0.962 rs2277769 chr20:61666805 C/T cg08564027 chr20:61660810 NA 0.4 7.92 0.39 3.45e-14 Prostate cancer (SNP x SNP interaction); LIHC cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs1008375 0.966 rs6832962 chr4:17652133 T/C cg02297831 chr4:17616191 MED28 0.42 5.95 0.31 6.57e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs735396 0.627 rs2264778 chr12:121450354 C/A cg02403541 chr12:121454288 C12orf43 0.72 13.84 0.6 6.68e-35 N-glycan levels; LIHC cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg03517284 chr6:25882590 NA -0.94 -13.68 -0.59 2.88e-34 Blood metabolite levels; LIHC cis rs12586317 0.514 rs74590021 chr14:35490113 T/G cg16230307 chr14:35515116 FAM177A1 0.79 13.35 0.59 5.37e-33 Psoriasis; LIHC cis rs9910055 0.593 rs58392387 chr17:42297889 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.36 6.55 0.33 2.06e-10 Total body bone mineral density; LIHC cis rs1577917 0.958 rs1447160 chr6:86546123 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC cis rs4474465 0.607 rs4945303 chr11:78283803 A/G cg27205649 chr11:78285834 NARS2 0.48 7.55 0.38 4.07e-13 Alzheimer's disease (survival time); LIHC cis rs2288912 0.620 rs875255 chr19:45493635 C/G cg09555818 chr19:45449301 APOC2 -0.2 -5.71 -0.3 2.41e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC cis rs7116495 0.609 rs2155145 chr11:71719619 G/T cg10381502 chr11:71823885 C11orf51 -1.06 -9.3 -0.45 1.74e-18 Severe influenza A (H1N1) infection; LIHC cis rs4450131 0.618 rs897306 chr10:126337060 T/C cg20435097 chr10:126320824 FAM53B -0.62 -11.71 -0.54 7.19e-27 White blood cell count (basophil); LIHC cis rs894734 0.567 rs7138907 chr12:54324576 C/T cg17708016 chr12:54321992 NA 0.4 7.1 0.36 7.29e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); LIHC cis rs7659604 1.000 rs10005932 chr4:122664782 T/C cg19748678 chr4:122722346 EXOSC9 0.35 5.86 0.3 1.06e-8 Type 2 diabetes; LIHC cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.68 0.8 5.83e-78 Prudent dietary pattern; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs2072499 0.865 rs2758603 chr1:156198994 T/C cg25208724 chr1:156163844 SLC25A44 0.6 10.35 0.49 5.03e-22 Testicular germ cell tumor; LIHC cis rs1552244 0.882 rs9757159 chr3:10039166 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.65 -10.24 -0.48 1.18e-21 Alzheimer's disease; LIHC cis rs8180040 0.676 rs13098228 chr3:47138253 A/G cg27129171 chr3:47204927 SETD2 0.69 12.26 0.55 7.14e-29 Colorectal cancer; LIHC cis rs9814567 1.000 rs2373865 chr3:134291556 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 0.43 6.14 0.32 2.3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1552244 0.554 rs59465469 chr3:9990800 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.55 7.81 0.39 7.09e-14 Alzheimer's disease; LIHC cis rs921968 0.565 rs7599568 chr2:219607819 A/G cg02985541 chr2:219472218 PLCD4 -0.37 -6.41 -0.33 4.97e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg03188948 chr7:1209495 NA 0.46 6.48 0.33 3.27e-10 Longevity;Endometriosis; LIHC cis rs1728785 0.901 rs933713 chr16:68581378 C/A cg02972257 chr16:68554789 NA -0.54 -6.14 -0.31 2.35e-9 Ulcerative colitis; LIHC cis rs67311347 1.000 rs2305522 chr3:40429358 A/G cg09455208 chr3:40491958 NA 0.35 6.97 0.35 1.65e-11 Renal cell carcinoma; LIHC cis rs7523273 0.606 rs2724380 chr1:207949682 C/T cg22525895 chr1:207977042 MIR29B2 0.63 10.22 0.48 1.38e-21 Schizophrenia; LIHC cis rs6424115 0.733 rs2502996 chr1:24199041 T/C cg10978503 chr1:24200527 CNR2 0.34 8.04 0.4 1.48e-14 Immature fraction of reticulocytes; LIHC cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg02187348 chr16:89574699 SPG7 0.65 10.19 0.48 1.74e-21 Multiple myeloma (IgH translocation); LIHC cis rs10779751 0.960 rs4845860 chr1:11324193 A/G cg08854313 chr1:11322531 MTOR 0.87 12.9 0.57 2.64e-31 Body mass index; LIHC cis rs739401 0.611 rs2239899 chr11:3024624 A/G cg05729581 chr11:3078854 CARS 0.47 6.58 0.34 1.73e-10 Longevity; LIHC cis rs9517320 0.515 rs9556969 chr13:99195948 T/C cg07423050 chr13:99094983 FARP1 -0.51 -9.04 -0.44 1.16e-17 Longevity; LIHC trans rs7618501 0.735 rs9876508 chr3:49780844 G/A cg21659725 chr3:3221576 CRBN -0.98 -19.57 -0.73 9.08e-58 Intelligence (multi-trait analysis); LIHC cis rs17685 0.753 rs11764129 chr7:75761890 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.38 -6.24 -0.32 1.28e-9 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs3008870 0.755 rs2815365 chr1:67499628 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.67 11.31 0.52 2.1e-25 Lymphocyte percentage of white cells; LIHC cis rs7188697 0.922 rs37040 chr16:58578262 T/C cg02549819 chr16:58548995 SETD6 -0.46 -7.27 -0.37 2.47e-12 QT interval; LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.78 0.62 1.38e-38 Prudent dietary pattern; LIHC trans rs561341 1.000 rs56362439 chr17:30253140 T/A cg20587970 chr11:113659929 NA -0.65 -7.34 -0.37 1.52e-12 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg18252515 chr7:66147081 NA -1.3 -16.89 -0.67 5.67e-47 Diabetic kidney disease; LIHC trans rs17060993 0.618 rs17056484 chr8:26848328 C/T cg03294066 chr8:494721 C8orf42 0.71 6.19 0.32 1.73e-9 Musician's dystonia; LIHC cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg27572855 chr1:25598939 RHD -0.37 -7.84 -0.39 5.89e-14 Erythrocyte sedimentation rate; LIHC cis rs7582720 1.000 rs114527590 chr2:203787405 A/G cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg07677032 chr17:61819896 STRADA 0.43 6.14 0.32 2.25e-9 Prudent dietary pattern; LIHC cis rs80282103 0.618 rs74120451 chr10:1126866 T/C cg08668510 chr10:1095578 IDI1 0.68 6.62 0.34 1.41e-10 Glomerular filtration rate (creatinine); LIHC cis rs1018836 0.527 rs13268721 chr8:91481549 G/A cg16814680 chr8:91681699 NA -0.41 -6.65 -0.34 1.15e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg21724239 chr8:58056113 NA 0.57 7.57 0.38 3.45e-13 Developmental language disorder (linguistic errors); LIHC cis rs7568458 0.636 rs11126995 chr2:85792408 A/T cg02493740 chr2:85810744 VAMP5 -0.5 -8.23 -0.41 4.01e-15 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs7249142 0.549 rs1858846 chr19:19281187 T/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.41 -6.78 -0.34 5.43e-11 IgG glycosylation; LIHC cis rs4665809 1.000 rs6709595 chr2:26259885 A/G cg04944784 chr2:26401820 FAM59B -0.68 -8.71 -0.43 1.37e-16 Gut microbiome composition (summer); LIHC cis rs9818758 0.607 rs35283189 chr3:49113668 T/C cg00383909 chr3:49044727 WDR6 0.85 7.04 0.36 1.09e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 8.53 0.42 4.82e-16 Platelet count; LIHC cis rs7552404 0.961 rs17587071 chr1:76225083 A/C cg10523679 chr1:76189770 ACADM 0.64 8.72 0.43 1.2e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6089829 0.851 rs4809460 chr20:61661355 T/C cg03213289 chr20:61660250 NA 0.51 9.1 0.44 7.55e-18 Prostate cancer (SNP x SNP interaction); LIHC cis rs611744 0.967 rs689256 chr8:109186398 T/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9790314 1.000 rs336577 chr3:161066294 C/T cg04691961 chr3:161091175 C3orf57 -0.42 -6.67 -0.34 1.03e-10 Morning vs. evening chronotype; LIHC cis rs507080 0.922 rs7114458 chr11:118566175 G/A cg04173919 chr11:118528438 PHLDB1 0.36 6.68 0.34 9.83e-11 Serum metabolite levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04249525 chr7:152373324 XRCC2 -0.44 -6.19 -0.32 1.76e-9 Pancreatic cancer; LIHC cis rs2921073 0.605 rs2976933 chr8:8254875 A/G cg08975724 chr8:8085496 FLJ10661 0.51 7.49 0.38 5.8e-13 Parkinson's disease; LIHC cis rs734999 0.588 rs11585048 chr1:2534087 C/T cg18854424 chr1:2615690 NA 0.32 7.11 0.36 6.89e-12 Ulcerative colitis; LIHC cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg00166722 chr3:10149974 C3orf24 0.51 5.87 0.3 1e-8 Alzheimer's disease; LIHC cis rs72781680 0.898 rs72780191 chr2:24007122 T/C cg08917208 chr2:24149416 ATAD2B 0.96 8.09 0.4 1.02e-14 Lymphocyte counts; LIHC cis rs1552244 1.000 rs7626117 chr3:10140671 G/A cg08888203 chr3:10149979 C3orf24 0.5 6.25 0.32 1.21e-9 Alzheimer's disease; LIHC cis rs868036 0.681 rs4776977 chr15:68108219 C/T cg24579218 chr15:68104479 NA -0.35 -5.91 -0.3 8.1e-9 Restless legs syndrome; LIHC cis rs7520050 0.807 rs28647556 chr1:46206399 G/A cg24296786 chr1:45957014 TESK2 -0.4 -5.88 -0.3 9.62e-9 Red blood cell count;Reticulocyte count; LIHC cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg10217327 chr6:118973057 C6orf204 0.69 7.04 0.36 1.03e-11 Diastolic blood pressure; LIHC cis rs61677309 1.000 rs61390396 chr11:118156718 C/T cg06090739 chr11:118230722 UBE4A 0.35 6.59 0.34 1.71e-10 Lung cancer in ever smokers; LIHC cis rs7959452 0.649 rs4761239 chr12:69776886 T/A cg14784868 chr12:69753453 YEATS4 0.92 18.65 0.71 4.53e-54 Blood protein levels; LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg06791812 chr14:105677543 BRF1 0.53 6.46 0.33 3.65e-10 Lung function (FEV1); LIHC cis rs11628318 0.588 rs12892602 chr14:103114091 T/C cg12046867 chr14:103022105 NA 0.43 6.74 0.34 6.63e-11 Platelet count; LIHC cis rs2303759 0.918 rs10405465 chr19:49869298 C/T cg22307029 chr19:49891270 CCDC155 0.56 9.07 0.44 9.29e-18 Multiple sclerosis; LIHC cis rs62458065 0.640 rs10274556 chr7:32513947 A/G cg06627557 chr7:32535165 LSM5;AVL9 -0.66 -6.55 -0.33 2.15e-10 Metabolite levels (HVA/MHPG ratio); LIHC cis rs1059312 0.778 rs4760594 chr12:129296865 T/A cg09035930 chr12:129282057 SLC15A4 0.6 11.2 0.52 5.04e-25 Systemic lupus erythematosus; LIHC cis rs903552 0.935 rs4965871 chr15:102003810 A/T cg06707286 chr15:102010195 PCSK6 -0.44 -6.48 -0.33 3.2e-10 Diabetic kidney disease; LIHC cis rs4423214 0.798 rs1894100 chr11:71130343 G/T cg24826892 chr11:71159390 DHCR7 -0.46 -5.71 -0.3 2.41e-8 Vitamin D levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11328140 chr12:108079443 PWP1 0.49 7.19 0.36 4.02e-12 Cognitive function; LIHC cis rs4423214 1.000 rs2852853 chr11:71150217 C/T cg05163923 chr11:71159392 DHCR7 0.92 14.42 0.61 3.81e-37 Vitamin D levels; LIHC cis rs2153535 0.580 rs2327062 chr6:8453858 G/A cg21535247 chr6:8435926 SLC35B3 0.65 8.63 0.42 2.27e-16 Motion sickness; LIHC trans rs11165623 0.602 rs11165667 chr1:97013509 A/C cg10631902 chr5:14652156 NA -0.25 -6.33 -0.32 7.54e-10 Hip circumference;Waist circumference; LIHC cis rs11630290 0.592 rs1912048 chr15:64155974 G/A cg12036633 chr15:63758958 NA 0.64 6.79 0.34 4.95e-11 Iris characteristics; LIHC cis rs77669868 0.929 rs3782004 chr11:114070250 T/C cg01914181 chr11:114070210 ZBTB16 0.65 9.07 0.44 9.62e-18 Monocyte percentage of white cells; LIHC cis rs7131987 0.903 rs2194519 chr12:29423583 C/T cg00204748 chr12:29376779 FAR2 -0.41 -7.74 -0.39 1.16e-13 QT interval; LIHC cis rs3096299 0.967 rs2965932 chr16:89477051 C/T cg08822215 chr16:89438651 ANKRD11 0.46 7.24 0.36 2.94e-12 Multiple myeloma (IgH translocation); LIHC cis rs2191566 0.821 rs62119173 chr19:44518073 G/A cg20607764 chr19:44506953 ZNF230 -0.41 -6.7 -0.34 8.82e-11 Acute lymphoblastic leukemia (childhood); LIHC cis rs4253772 0.591 rs7291444 chr22:46656246 T/G cg09491104 chr22:46646882 C22orf40 -0.65 -7.54 -0.38 4.39e-13 LDL cholesterol;Cholesterol, total; LIHC cis rs9929218 0.906 rs10852450 chr16:68749529 G/A cg01231543 chr16:68741748 NA 0.38 6.12 0.31 2.55e-9 Colorectal cancer; LIHC cis rs7428 0.527 rs1053560 chr2:85546192 C/T cg24342717 chr2:85555507 TGOLN2 -0.79 -10.24 -0.48 1.19e-21 Ear protrusion; LIHC cis rs35883536 1.000 rs12566507 chr1:101089679 T/A cg14515779 chr1:101123966 NA -0.68 -13.21 -0.58 1.78e-32 Monocyte count; LIHC cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg24642844 chr7:1081250 C7orf50 -0.92 -8.96 -0.44 2.13e-17 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs6963495 0.818 rs56165465 chr7:105180384 C/T cg19920283 chr7:105172520 RINT1 0.66 6.42 0.33 4.55e-10 Bipolar disorder (body mass index interaction); LIHC cis rs9549367 0.713 rs9549357 chr13:113860121 C/T cg00898013 chr13:113819073 PROZ -0.39 -7.06 -0.36 9.05e-12 Platelet distribution width; LIHC cis rs2576037 0.558 rs7244778 chr18:44541915 T/C cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.09 -0.36 7.73e-12 Personality dimensions; LIHC cis rs2153535 0.601 rs7738877 chr6:8542230 A/G cg07606381 chr6:8435919 SLC35B3 0.74 11.26 0.52 3.18e-25 Motion sickness; LIHC cis rs12980942 1.000 rs3826714 chr19:41825776 A/G cg25627403 chr19:41769009 HNRNPUL1 0.47 5.91 0.3 8.07e-9 Coronary artery disease; LIHC cis rs4808199 0.947 rs7250658 chr19:19571100 A/G cg03709012 chr19:19516395 GATAD2A 1.09 19.27 0.72 1.51e-56 Nonalcoholic fatty liver disease; LIHC cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg00684032 chr4:1343700 KIAA1530 0.52 7.59 0.38 3.1e-13 Obesity-related traits; LIHC cis rs1866706 0.964 rs1866710 chr11:12875312 A/G cg25843174 chr11:12811716 TEAD1 -0.29 -6.16 -0.32 2.04e-9 Intelligence (multi-trait analysis); LIHC cis rs3741798 1.000 rs61922026 chr12:12486428 C/G cg08615371 chr12:12503544 MANSC1 0.98 7.84 0.39 5.9e-14 Cerebrospinal fluid biomarker levels; LIHC cis rs6952808 0.595 rs3778982 chr7:2166233 T/C cg02951883 chr7:2050386 MAD1L1 -0.65 -10.62 -0.5 5.84e-23 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg11062466 chr8:58055876 NA 0.39 5.72 0.3 2.34e-8 Developmental language disorder (linguistic errors); LIHC cis rs7917772 0.636 rs7069489 chr10:104525371 A/G cg22532475 chr10:104410764 TRIM8 -0.36 -6.48 -0.33 3.21e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11098499 0.909 rs28555550 chr4:120211040 C/G cg09307838 chr4:120376055 NA 0.72 10.66 0.5 4.1000000000000003e-23 Corneal astigmatism; LIHC cis rs72781680 1.000 rs17711825 chr2:24124578 A/G cg08917208 chr2:24149416 ATAD2B 0.79 7.61 0.38 2.61e-13 Lymphocyte counts; LIHC cis rs55665837 1.000 rs10466412 chr11:14505189 A/T cg19336497 chr11:14380999 RRAS2 -0.45 -8.21 -0.41 4.42e-15 Vitamin D levels; LIHC cis rs1843834 0.574 rs6436499 chr2:225456551 A/T cg22455342 chr2:225449267 CUL3 0.6 8.72 0.43 1.24e-16 IgE levels in asthmatics (D.p. specific); LIHC cis rs2303759 0.874 rs8108669 chr19:49845895 C/T cg22307029 chr19:49891270 CCDC155 0.57 9.29 0.45 1.8e-18 Multiple sclerosis; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg01171360 chr6:293285 DUSP22 0.44 6.44 0.33 4e-10 Menopause (age at onset); LIHC cis rs16958440 1.000 rs62096470 chr18:44641466 G/C cg17192377 chr18:44677553 HDHD2 0.61 6.9 0.35 2.59e-11 Sitting height ratio; LIHC cis rs7772486 0.875 rs9390377 chr6:146386932 G/A cg05347473 chr6:146136440 FBXO30 0.37 5.89 0.3 9.41e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs9303401 0.659 rs714959 chr17:56628601 A/G cg25039879 chr17:56429692 SUPT4H1 0.75 8.46 0.42 7.8e-16 Cognitive test performance; LIHC cis rs763121 0.925 rs1056661 chr22:39080245 A/G cg21395723 chr22:39101663 GTPBP1 0.34 5.77 0.3 1.77e-8 Menopause (age at onset); LIHC cis rs2933343 0.700 rs1683787 chr3:128627021 C/T cg25356066 chr3:128598488 ACAD9 -0.53 -7.47 -0.37 6.56e-13 IgG glycosylation; LIHC cis rs875971 0.862 rs2088653 chr7:65808608 G/A cg18252515 chr7:66147081 NA 0.46 6.86 0.35 3.33e-11 Aortic root size; LIHC trans rs916888 0.773 rs199535 chr17:44822662 A/G cg22968622 chr17:43663579 NA 1.19 12.97 0.57 1.52e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.78 0.62 1.38e-38 Prudent dietary pattern; LIHC cis rs875971 0.964 rs6978721 chr7:65883204 A/G cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs7336332 0.598 rs75439483 chr13:28010512 A/G cg22138327 chr13:27999177 GTF3A 0.5 5.73 0.3 2.2e-8 Weight; LIHC cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg05564831 chr3:52568323 NT5DC2 0.38 6.18 0.32 1.83e-9 Bipolar disorder; LIHC cis rs10751667 0.643 rs10902234 chr11:935578 A/G ch.11.42038R chr11:967971 AP2A2 0.55 10.04 0.48 5.67e-21 Alzheimer's disease (late onset); LIHC cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg18252515 chr7:66147081 NA -1.3 -16.78 -0.67 1.58e-46 Diabetic kidney disease; LIHC cis rs3617 0.625 rs7620690 chr3:52891707 A/G cg11645453 chr3:52864694 ITIH4 -0.23 -6.16 -0.32 2.1e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs6141600 0.574 rs2746088 chr20:34643323 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.39 -6.19 -0.32 1.72e-9 Height;Hip circumference; LIHC cis rs7212590 0.748 rs7211208 chr17:57957109 A/C cg10252138 chr17:58120427 NA -0.62 -6.61 -0.34 1.44e-10 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs611744 0.573 rs629996 chr8:109255206 C/T cg18478394 chr8:109455254 TTC35 0.38 6.54 0.33 2.25e-10 Dupuytren's disease; LIHC cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg12311346 chr5:56204834 C5orf35 -0.64 -8.23 -0.41 4e-15 Type 2 diabetes; LIHC cis rs1008375 0.966 rs6813375 chr4:17649499 T/G cg16339924 chr4:17578868 LAP3 0.44 6.11 0.31 2.65e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs262150 0.545 rs73167302 chr7:158789762 G/A cg13444538 chr7:158905317 VIPR2 -0.33 -6.15 -0.32 2.16e-9 Facial morphology (factor 20); LIHC trans rs854462 1.000 rs854462 chr17:34386090 C/T cg16820615 chr13:114884918 RASA3 -0.51 -6.14 -0.32 2.29e-9 Blood protein levels; LIHC cis rs6088590 0.561 rs764597 chr20:33161225 C/T cg08999081 chr20:33150536 PIGU 0.68 13.55 0.59 8.63e-34 Coronary artery disease; LIHC cis rs7523273 0.565 rs1998539 chr1:207886596 G/A cg22525895 chr1:207977042 MIR29B2 0.52 7.78 0.39 8.74e-14 Schizophrenia; LIHC cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg05590025 chr7:65112418 INTS4L2 -0.62 -6.82 -0.35 4.26e-11 Diabetic kidney disease; LIHC cis rs7917772 0.536 rs11191361 chr10:104411958 C/T cg22532475 chr10:104410764 TRIM8 -0.4 -6.74 -0.34 6.75e-11 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs986417 0.818 rs7144656 chr14:61032909 A/G cg27398547 chr14:60952738 C14orf39 0.68 7.77 0.39 9.52e-14 Gut microbiota (bacterial taxa); LIHC cis rs941408 1.000 rs1640273 chr19:2803227 C/T cg06609049 chr19:2785107 THOP1 0.55 9.62 0.46 1.49e-19 Total cholesterol levels; LIHC cis rs79839061 0.518 rs3755961 chr4:895059 A/G cg07828340 chr4:882639 GAK 0.78 6.47 0.33 3.38e-10 Intelligence (multi-trait analysis); LIHC cis rs780094 0.544 rs780108 chr2:27684957 T/C cg27432699 chr2:27873401 GPN1 -0.43 -5.95 -0.31 6.71e-9 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; LIHC cis rs12594515 1.000 rs8039974 chr15:45986665 A/G cg06207120 chr15:45996521 NA 0.33 6.36 0.33 6.37e-10 Waist circumference;Weight; LIHC cis rs3762637 0.943 rs9841897 chr3:122282569 T/C cg24169773 chr3:122142474 KPNA1 -0.45 -8.86 -0.43 4.49e-17 LDL cholesterol levels; LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg14159672 chr1:205819179 PM20D1 0.69 9.65 0.46 1.17e-19 Menarche (age at onset); LIHC cis rs7833986 0.501 rs72653957 chr8:56990048 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.52 0.42 5.06e-16 Height; LIHC cis rs10832963 0.961 rs10832954 chr11:18643559 G/A cg09201001 chr11:18656081 SPTY2D1 0.94 17.62 0.69 6.46e-50 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06914197 chr12:6586920 NA 0.38 6.12 0.31 2.56e-9 Pancreatic cancer; LIHC cis rs600806 0.815 rs3768495 chr1:109935325 C/T cg23091122 chr1:110024289 SYPL2 -0.47 -6.35 -0.32 6.88e-10 Intelligence (multi-trait analysis); LIHC trans rs61931739 0.613 rs1817500 chr12:33679809 G/T cg14927277 chr11:28129967 METT5D1;KIF18A 0.46 6.82 0.35 4.09e-11 Morning vs. evening chronotype; LIHC cis rs80282103 0.867 rs12241632 chr10:1069070 A/T cg20335179 chr10:1068567 C10orf110;IDI2 -0.56 -6.43 -0.33 4.32e-10 Glomerular filtration rate (creatinine); LIHC cis rs2637030 0.515 rs1844696 chr5:52936538 A/C cg06476337 chr5:52856530 NDUFS4 0.42 6.38 0.33 5.78e-10 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs780096 0.587 rs6743819 chr2:27567407 G/T cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.39 -6.0 -0.31 4.96e-9 Total body bone mineral density; LIHC cis rs700651 0.789 rs1978889 chr2:198889366 G/A cg00792783 chr2:198669748 PLCL1 0.41 5.93 0.31 7.58e-9 Intracranial aneurysm; LIHC cis rs7089973 0.604 rs11196937 chr10:116589500 G/C cg23260525 chr10:116636907 FAM160B1 0.35 6.99 0.35 1.41e-11 Bipolar disorder or attention deficit hyperactivity disorder; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg03258011 chr17:54857409 NA 0.48 6.53 0.33 2.41e-10 Pancreatic cancer; LIHC cis rs7582720 1.000 rs72932781 chr2:203697278 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.72 5.79 0.3 1.57e-8 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs9916302 0.904 rs35335692 chr17:37710006 A/G cg07936489 chr17:37558343 FBXL20 -0.83 -13.31 -0.58 7.63e-33 Glomerular filtration rate (creatinine); LIHC cis rs2455799 0.573 rs2455836 chr3:15754538 A/G cg12698662 chr3:15914712 MIR563 -0.4 -7.43 -0.37 8.57e-13 Mean platelet volume; LIHC cis rs5769765 1.000 rs34774661 chr22:50267508 C/G cg02269571 chr22:50332266 NA 0.6 8.51 0.42 5.42e-16 Schizophrenia; LIHC cis rs727563 0.635 rs713988 chr22:42159072 A/G cg06634786 chr22:41940651 POLR3H 0.75 7.57 0.38 3.48e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs916888 0.821 rs199514 chr17:44856881 G/A cg15921436 chr17:44337874 NA -0.66 -6.79 -0.34 5.03e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs9303401 1.000 rs9904677 chr17:56873025 A/G cg12560992 chr17:57184187 TRIM37 0.73 10.84 0.51 9.51e-24 Cognitive test performance; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01831166 chr2:198570100 MARS2 -0.48 -6.77 -0.34 5.48e-11 Pancreatic cancer; LIHC cis rs2932538 0.922 rs12138335 chr1:113122760 T/C cg22162597 chr1:113214053 CAPZA1 0.71 9.59 0.46 1.87e-19 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs611744 0.805 rs378515 chr8:109104905 T/G cg21045802 chr8:109455806 TTC35 0.48 8.24 0.41 3.61e-15 Dupuytren's disease; LIHC cis rs7659604 0.702 rs61217486 chr4:122693973 T/C cg19748678 chr4:122722346 EXOSC9 0.64 10.73 0.5 2.37e-23 Type 2 diabetes; LIHC cis rs7712401 0.791 rs10059964 chr5:122118293 A/G cg18764291 chr5:122110994 SNX2 0.35 5.94 0.31 7.13e-9 Mean platelet volume; LIHC cis rs11608355 0.515 rs34038572 chr12:109901657 A/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs875971 0.638 rs7793569 chr7:66116633 T/G cg14393609 chr7:65229607 NA -0.37 -5.85 -0.3 1.18e-8 Aortic root size; LIHC cis rs600806 0.850 rs10858092 chr1:109943893 A/G cg08911820 chr1:110026001 ATXN7L2 0.59 7.31 0.37 1.9e-12 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.68 0.46 9.5e-20 Bipolar disorder; LIHC cis rs8180040 0.629 rs7426969 chr3:47091355 T/C cg27129171 chr3:47204927 SETD2 0.56 9.23 0.45 2.84e-18 Colorectal cancer; LIHC cis rs1577917 0.958 rs2324839 chr6:86536942 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.23 -0.41 4.11e-15 Response to antipsychotic treatment; LIHC cis rs2257205 0.588 rs77430462 chr17:56804085 C/G cg12560992 chr17:57184187 TRIM37 0.72 7.97 0.4 2.33e-14 Pancreatic cancer; LIHC cis rs4742903 0.967 rs10820599 chr9:106856691 T/G cg14250997 chr9:106856677 SMC2 0.43 7.37 0.37 1.32e-12 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg07424592 chr7:64974309 NA 0.85 9.18 0.44 4.11e-18 Diabetic kidney disease; LIHC cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg26566898 chr11:117069891 TAGLN -0.47 -7.33 -0.37 1.63e-12 Blood protein levels; LIHC cis rs738321 0.757 rs5750546 chr22:38542499 C/T cg25457927 chr22:38595422 NA -0.35 -7.84 -0.39 5.64e-14 Breast cancer; LIHC cis rs11676348 0.714 rs4674254 chr2:218986077 T/C cg00012203 chr2:219082015 ARPC2 -0.55 -7.69 -0.38 1.53e-13 Ulcerative colitis; LIHC cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg24101359 chr6:42928495 GNMT -0.48 -6.41 -0.33 4.88e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs909002 0.800 rs3753612 chr1:32082410 C/G cg13919466 chr1:32135498 COL16A1 -0.32 -6.18 -0.32 1.8e-9 Intelligence (multi-trait analysis); LIHC cis rs34172651 0.517 rs3803716 chr16:24802325 C/T cg00339695 chr16:24857497 SLC5A11 0.73 10.77 0.5 1.7e-23 Intelligence (multi-trait analysis); LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg11905131 chr22:24372483 LOC391322 -0.65 -9.76 -0.47 5.17e-20 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs77637988 0.578 rs6718068 chr2:48604978 C/T cg00032884 chr2:48540671 FOXN2 0.4 6.35 0.32 6.67e-10 Joint mobility (Beighton score); LIHC cis rs1707322 1.000 rs785490 chr1:46577124 T/C cg06784218 chr1:46089804 CCDC17 -0.4 -7.22 -0.36 3.38e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs72960926 0.744 rs56077244 chr6:74920700 A/G cg07247405 chr1:2484626 LOC115110 0.55 6.51 0.33 2.71e-10 Metabolite levels (MHPG); LIHC cis rs4808199 0.895 rs10419672 chr19:19471241 T/C cg03709012 chr19:19516395 GATAD2A 1.02 16.94 0.68 3.58e-47 Nonalcoholic fatty liver disease; LIHC cis rs2832191 0.729 rs2832201 chr21:30499841 A/G cg24692254 chr21:30365293 RNF160 -0.79 -13.32 -0.58 6.54e-33 Dental caries; LIHC cis rs853679 0.517 rs6941992 chr6:28106141 T/C cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs3741404 0.609 rs592271 chr11:63872029 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 11.06 0.51 1.58e-24 Platelet count; LIHC cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg09417038 chr21:47716443 C21orf57 -0.53 -7.99 -0.4 2.09e-14 Testicular germ cell tumor; LIHC cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.25e-9 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.855 rs11253468 chr10:903261 G/A cg26597838 chr10:835615 NA 1.17 13.77 0.6 1.22e-34 Eosinophil percentage of granulocytes; LIHC cis rs9399135 0.967 rs13199205 chr6:135286505 T/C cg24558204 chr6:135376177 HBS1L 0.39 6.49 0.33 3.01e-10 Red blood cell count; LIHC cis rs9660992 0.573 rs1172161 chr1:205206495 C/T cg21545522 chr1:205238299 TMCC2 0.37 7.1 0.36 7.18e-12 Mean corpuscular volume;Mean platelet volume; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg19569686 chr19:1555141 MEX3D 0.36 6.17 0.32 1.94e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs6964587 0.758 rs35963176 chr7:91617115 C/T cg17063962 chr7:91808500 NA 0.73 7.72 0.39 1.3e-13 Breast cancer; LIHC cis rs10751667 0.600 rs6597948 chr11:1005308 C/T cg10932868 chr11:921992 NA 0.34 6.28 0.32 1.06e-9 Alzheimer's disease (late onset); LIHC cis rs12824058 0.831 rs7485200 chr12:130811641 C/T cg24229701 chr12:130821962 PIWIL1 0.45 6.8 0.35 4.72e-11 Menopause (age at onset); LIHC cis rs3806843 0.966 rs11741994 chr5:140145949 G/A cg19875535 chr5:140030758 IK 0.38 6.22 0.32 1.45e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs1403694 0.966 rs9869244 chr3:186437554 A/T cg12454167 chr3:186435060 KNG1 0.3 7.28 0.37 2.25e-12 Blood protein levels; LIHC cis rs12477438 0.520 rs4850897 chr2:99768419 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.59 10.81 0.5 1.22e-23 Chronic sinus infection; LIHC trans rs1499614 1.000 rs2659911 chr7:66158420 G/A cg07424592 chr7:64974309 NA 0.77 8.92 0.43 2.81e-17 Gout; LIHC cis rs4906332 1.000 rs7155980 chr14:103922419 C/G cg26031613 chr14:104095156 KLC1 -0.41 -5.77 -0.3 1.76e-8 Coronary artery disease; LIHC cis rs9556958 0.708 rs9513435 chr13:99160334 C/G cg15168958 chr13:99100528 FARP1 0.34 5.89 0.3 9.21e-9 Educational attainment (years of education); LIHC cis rs9381040 1.000 rs2093396 chr6:41155000 G/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.95 -0.31 6.48e-9 Alzheimer's disease (late onset); LIHC cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg11062466 chr8:58055876 NA 0.49 6.67 0.34 1.04e-10 Developmental language disorder (linguistic errors); LIHC cis rs7572733 0.515 rs12619300 chr2:198786490 A/C cg03934865 chr2:198174659 NA -0.46 -6.7 -0.34 8.86e-11 Dermatomyositis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04371633 chr14:65381025 CHURC1 0.44 6.27 0.32 1.12e-9 Pancreatic cancer; LIHC cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg06634786 chr22:41940651 POLR3H 0.82 9.19 0.45 3.76e-18 Vitiligo; LIHC trans rs1814175 0.817 rs1794164 chr11:49899610 T/C cg18944383 chr4:111397179 ENPEP 0.27 7.06 0.36 9.34e-12 Height; LIHC cis rs801193 0.839 rs12534943 chr7:66070520 A/G cg11764359 chr7:65958608 NA -0.62 -9.36 -0.45 1.08e-18 Aortic root size; LIHC cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg23172400 chr8:95962367 TP53INP1 -0.38 -8.82 -0.43 6.01e-17 Type 2 diabetes; LIHC cis rs963731 0.649 rs1377860 chr2:39290425 C/G cg04010122 chr2:39346883 SOS1 0.73 6.59 0.34 1.68e-10 Corticobasal degeneration; LIHC cis rs10751667 0.643 rs7395613 chr11:933873 C/T cg11406765 chr11:980039 AP2A2 -0.35 -5.78 -0.3 1.69e-8 Alzheimer's disease (late onset); LIHC cis rs950169 0.650 rs12902052 chr15:85125838 A/T cg12863693 chr15:85201151 NMB 0.44 5.96 0.31 6.21e-9 Schizophrenia; LIHC cis rs8062405 0.754 rs3859172 chr16:28566158 G/T cg07451762 chr16:28383216 NA 0.33 6.75 0.34 6.39e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9513627 0.920 rs7335315 chr13:100121308 G/A cg25919922 chr13:100150906 NA -0.8 -7.05 -0.36 9.87e-12 Obesity-related traits; LIHC cis rs9291683 0.561 rs3733584 chr4:10036506 T/C cg11266682 chr4:10021025 SLC2A9 0.35 7.45 0.37 7.45e-13 Bone mineral density; LIHC cis rs3812111 0.677 rs1204796 chr6:116541503 T/C cg08036074 chr6:116424633 NT5DC1 -0.4 -6.5 -0.33 2.91e-10 Age-related macular degeneration; LIHC cis rs208520 0.690 rs851467 chr6:66802721 A/G cg07460842 chr6:66804631 NA -0.84 -9.29 -0.45 1.86e-18 Exhaled nitric oxide output; LIHC cis rs28595532 0.748 rs115651241 chr4:119363509 C/T cg21605333 chr4:119757512 SEC24D 1.07 8.66 0.42 1.91e-16 Cannabis dependence symptom count; LIHC cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg13607699 chr17:42295918 UBTF -0.63 -11.39 -0.52 1.04e-25 Total body bone mineral density; LIHC cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg15691649 chr6:25882328 NA -0.53 -7.62 -0.38 2.55e-13 Blood metabolite levels; LIHC cis rs56146971 0.763 rs45490092 chr14:91845143 A/G cg16433844 chr14:91963127 SMEK1 -0.58 -6.11 -0.31 2.72e-9 Alzheimer disease and age of onset; LIHC cis rs2115630 0.905 rs1975277 chr15:85329558 C/T cg09876464 chr15:85330779 ZNF592 0.35 6.02 0.31 4.58e-9 P wave terminal force; LIHC cis rs17401966 1.000 rs11121533 chr1:10292888 G/C cg19773385 chr1:10388646 KIF1B -0.47 -8.19 -0.41 5.14e-15 Hepatocellular carcinoma; LIHC cis rs2204008 0.775 rs11182513 chr12:38560252 G/C cg26384229 chr12:38710491 ALG10B 0.97 12.66 0.56 2.12e-30 Bladder cancer; LIHC cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC cis rs9325144 0.647 rs10875953 chr12:39050536 G/C cg26384229 chr12:38710491 ALG10B -0.4 -5.75 -0.3 1.93e-8 Morning vs. evening chronotype; LIHC cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.45 0.46 5.54e-19 Bipolar disorder; LIHC cis rs4423214 0.840 rs1790341 chr11:71177578 T/C cg05163923 chr11:71159392 DHCR7 -0.61 -8.14 -0.4 7.36e-15 Vitamin D levels; LIHC trans rs35110281 0.805 rs2838330 chr21:45023876 T/A cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.48 6.7 0.34 8.77e-11 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC cis rs1144333 1.000 rs5745392 chr1:76306809 C/T cg10523679 chr1:76189770 ACADM 0.46 6.67 0.34 1.05e-10 Attention function in attention deficit hyperactive disorder; LIHC cis rs57502260 0.704 rs2186937 chr11:68256847 G/A cg16797656 chr11:68205561 LRP5 0.46 5.87 0.3 1.04e-8 Total body bone mineral density (age 45-60); LIHC cis rs4660261 0.526 rs2906458 chr1:44336389 A/G cg13606994 chr1:44402422 ARTN 0.32 5.88 0.3 1e-8 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg20607798 chr8:58055168 NA 0.63 8.02 0.4 1.71e-14 Developmental language disorder (linguistic errors); LIHC cis rs11690935 0.959 rs7586207 chr2:172671094 A/G cg13550731 chr2:172543902 DYNC1I2 -0.92 -17.4 -0.69 4.9e-49 Schizophrenia; LIHC cis rs3749237 0.595 rs4855859 chr3:49526300 C/T cg03060546 chr3:49711283 APEH 0.63 10.23 0.48 1.35e-21 Resting heart rate; LIHC trans rs877282 0.945 rs17293517 chr10:778770 C/T cg22713356 chr15:30763199 NA 1.34 12.43 0.56 1.62e-29 Uric acid levels; LIHC cis rs477895 1.000 rs7939107 chr11:64034773 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.81 7.92 0.39 3.26e-14 Mean platelet volume; LIHC cis rs7267979 0.966 rs2257712 chr20:25264910 T/C cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.72 0.34 7.46e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg20403628 chr5:121297515 SRFBP1 0.49 7.52 0.38 4.71e-13 Calcium levels; LIHC cis rs17253792 0.545 rs35294669 chr14:56017438 T/A cg01858014 chr14:56050164 KTN1 -0.69 -6.33 -0.32 7.61e-10 Putamen volume; LIHC cis rs611744 0.743 rs2514843 chr8:109063434 C/T cg21045802 chr8:109455806 TTC35 0.48 7.97 0.4 2.44e-14 Dupuytren's disease; LIHC cis rs7618501 0.699 rs1317154 chr3:49910084 T/C cg24110177 chr3:50126178 RBM5 -0.5 -7.79 -0.39 7.92e-14 Intelligence (multi-trait analysis); LIHC cis rs8062405 1.000 rs62036622 chr16:28837203 T/G cg00204512 chr16:28754710 NA 0.37 6.72 0.34 7.75e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs4845459 0.967 rs4845447 chr1:152590886 T/C cg20634798 chr1:152595351 LCE3A -0.32 -6.2 -0.32 1.63e-9 Psoriasis; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05617300 chr19:59093449 MGC2752 0.46 6.57 0.33 1.86e-10 Pancreatic cancer; LIHC cis rs9303401 0.538 rs2240258 chr17:56458183 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.85 10.5 0.49 1.6e-22 Cognitive test performance; LIHC cis rs748404 0.697 rs574065 chr15:43550655 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.43 -6.55 -0.33 2.17e-10 Lung cancer; LIHC cis rs801193 0.761 rs2659888 chr7:66230171 T/G cg11764359 chr7:65958608 NA 0.71 10.63 0.5 5.5e-23 Aortic root size; LIHC cis rs7572733 0.534 rs700678 chr2:198705820 T/C cg00792783 chr2:198669748 PLCL1 0.47 6.93 0.35 2.11e-11 Dermatomyositis; LIHC cis rs6582630 0.512 rs11182667 chr12:38588392 C/A cg26384229 chr12:38710491 ALG10B -0.51 -7.12 -0.36 6.58e-12 Drug-induced liver injury (flucloxacillin); LIHC cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg11494091 chr17:61959527 GH2 0.44 8.15 0.4 7.14e-15 Prudent dietary pattern; LIHC cis rs11792861 0.926 rs72607173 chr9:111879398 T/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.61 8.51 0.42 5.53e-16 Menarche (age at onset); LIHC cis rs74544699 1.000 rs499141 chr4:74768970 A/C cg16072462 chr4:74847758 PF4 0.55 5.74 0.3 2.11e-8 Growth-regulated protein alpha levels; LIHC cis rs10504229 0.679 rs10504217 chr8:58037522 A/G cg20607798 chr8:58055168 NA 0.46 6.62 0.34 1.42e-10 Developmental language disorder (linguistic errors); LIHC cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.88 -11.73 -0.54 6e-27 Alzheimer's disease; LIHC cis rs10097731 0.901 rs9298344 chr8:82043063 C/T cg25230327 chr8:82042993 NA -0.6 -8.12 -0.4 8.67e-15 Serum total protein level; LIHC cis rs35110281 0.627 rs56369437 chr21:44970275 A/G cg04455712 chr21:45112962 RRP1B 0.42 7.04 0.36 1.06e-11 Mean corpuscular volume; LIHC cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg26831259 chr4:1366826 KIAA1530 0.35 5.75 0.3 1.99e-8 Obesity-related traits; LIHC trans rs875971 1.000 rs7792762 chr7:66004138 T/C cg10756647 chr7:56101905 PSPH 0.47 7.01 0.35 1.29e-11 Aortic root size; LIHC cis rs6570726 0.935 rs415590 chr6:145851244 T/C cg23711669 chr6:146136114 FBXO30 0.57 10.13 0.48 2.95e-21 Lobe attachment (rater-scored or self-reported); LIHC trans rs7677751 0.806 rs1800810 chr4:55094031 C/G cg17183009 chr3:120277827 NA 0.52 6.11 0.31 2.73e-9 Corneal astigmatism; LIHC cis rs700651 0.789 rs1371663 chr2:198900305 C/T cg03934865 chr2:198174659 NA -0.44 -6.23 -0.32 1.41e-9 Intracranial aneurysm; LIHC cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg08345575 chr16:4524283 NMRAL1;HMOX2 0.44 6.12 0.31 2.51e-9 Schizophrenia; LIHC cis rs853679 0.517 rs17711801 chr6:28092307 C/G cg16479474 chr6:28041457 NA 0.46 6.51 0.33 2.71e-10 Depression; LIHC cis rs7617773 0.817 rs9834095 chr3:48327751 G/A cg11946769 chr3:48343235 NME6 0.87 11.32 0.52 1.96e-25 Coronary artery disease; LIHC cis rs7296418 0.961 rs949143 chr12:123595163 G/A cg06742321 chr12:123595122 PITPNM2 0.31 5.77 0.3 1.82e-8 Platelet count; LIHC cis rs1005277 0.541 rs1740741 chr10:38515334 C/T cg25427524 chr10:38739819 LOC399744 -0.75 -15.06 -0.63 1.09e-39 Extrinsic epigenetic age acceleration; LIHC cis rs6570726 0.791 rs11759979 chr6:145918881 C/T cg13319975 chr6:146136371 FBXO30 -0.42 -6.52 -0.33 2.53e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23223044 chr19:49990882 RPL13AP5;RPL13A 0.44 6.15 0.32 2.22e-9 Lung function (FEV1/FVC); LIHC trans rs1005277 0.505 rs7917943 chr10:38195811 T/A cg27523141 chr10:43048294 ZNF37B -0.39 -6.77 -0.34 5.57e-11 Extrinsic epigenetic age acceleration; LIHC cis rs9457247 1.000 rs10946198 chr6:167404432 C/T cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs10876993 0.855 rs1689601 chr12:58049557 G/A cg18357645 chr12:58087776 OS9 0.53 8.58 0.42 3.26e-16 Celiac disease or Rheumatoid arthritis; LIHC cis rs1005277 0.579 rs1780146 chr10:38517874 C/A cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.49e-9 Extrinsic epigenetic age acceleration; LIHC trans rs1814175 0.935 rs11040463 chr11:49685574 C/T cg15704280 chr7:45808275 SEPT13 -1.01 -21.63 -0.76 5.27e-66 Height; LIHC cis rs4474465 0.850 rs4579956 chr11:78232445 G/C cg27205649 chr11:78285834 NARS2 0.41 6.08 0.31 3.13e-9 Alzheimer's disease (survival time); LIHC cis rs2404602 0.716 rs1946650 chr15:76848463 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.96 0.31 6.3e-9 Blood metabolite levels; LIHC trans rs11098499 0.569 rs10023641 chr4:120258410 C/G cg25214090 chr10:38739885 LOC399744 0.44 7.36 0.37 1.34e-12 Corneal astigmatism; LIHC trans rs3780486 0.846 rs2209948 chr9:33138247 G/A cg20290983 chr6:43655470 MRPS18A 1.19 30.89 0.86 5.55e-101 IgG glycosylation; LIHC cis rs7100689 0.646 rs1934693 chr10:82125650 T/C cg01528321 chr10:82214614 TSPAN14 0.77 10.17 0.48 2.16e-21 Post bronchodilator FEV1; LIHC cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg10360139 chr7:1886902 MAD1L1 -0.4 -6.17 -0.32 1.92e-9 Bipolar disorder and schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16944159 chr2:62132759 COMMD1 0.44 6.45 0.33 3.92e-10 Pancreatic cancer; LIHC cis rs17376456 0.877 rs17083462 chr5:93462401 T/G cg25358565 chr5:93447407 FAM172A 1.1 10.17 0.48 2.15e-21 Diabetic retinopathy; LIHC cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg16262614 chr3:133464971 TF 0.29 6.34 0.32 7.33e-10 Iron status biomarkers; LIHC cis rs6964587 0.692 rs10236483 chr7:91797296 A/C cg17063962 chr7:91808500 NA 0.67 12.22 0.55 9.29e-29 Breast cancer; LIHC cis rs4773330 1.000 rs9301494 chr13:111821289 G/C cg26911804 chr13:111806221 ARHGEF7 0.62 6.21 0.32 1.52e-9 Bilirubin levels; LIHC trans rs6600671 1.000 rs2319969 chr1:121207335 A/G cg09829573 chr1:144692074 NBPF9 -0.41 -6.89 -0.35 2.65e-11 Hip geometry; LIHC cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.35 -0.32 6.73e-10 Bipolar disorder and schizophrenia; LIHC cis rs898097 0.841 rs11656358 chr17:80853956 G/A cg15664640 chr17:80829946 TBCD -0.75 -12.59 -0.56 3.94e-30 Breast cancer; LIHC cis rs11031096 0.754 rs3817657 chr11:4142592 T/C cg18678763 chr11:4115507 RRM1 -0.52 -8.04 -0.4 1.47e-14 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs611744 0.870 rs57723916 chr8:109191433 A/T cg21045802 chr8:109455806 TTC35 0.51 8.81 0.43 6.4e-17 Dupuytren's disease; LIHC cis rs4555082 0.834 rs2816653 chr14:105713973 A/G cg10792982 chr14:105748885 BRF1 0.44 6.02 0.31 4.58e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg18867708 chr6:26865862 GUSBL1 -0.56 -8.55 -0.42 4.13e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs8060686 0.545 rs17688076 chr16:68286427 C/A cg09835421 chr16:68378352 PRMT7 -0.54 -6.3 -0.32 9.14e-10 HDL cholesterol;Metabolic syndrome; LIHC trans rs1005277 0.579 rs2505198 chr10:38393183 A/C cg27523141 chr10:43048294 ZNF37B 0.37 6.4 0.33 5.12e-10 Extrinsic epigenetic age acceleration; LIHC cis rs758324 0.617 rs12719447 chr5:131118100 C/A cg06307176 chr5:131281290 NA 0.4 5.85 0.3 1.17e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs2050392 0.737 rs7898978 chr10:30699800 T/C cg25182066 chr10:30743637 MAP3K8 0.59 9.19 0.45 3.86e-18 Inflammatory bowel disease; LIHC cis rs12701220 0.894 rs12701406 chr7:1050283 G/A cg04498913 chr7:1135747 C7orf50 0.37 5.72 0.3 2.36e-8 Bronchopulmonary dysplasia; LIHC cis rs2439831 0.702 rs8033995 chr15:44013509 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.57 8.12 0.4 8.82e-15 Lung cancer in ever smokers; LIHC cis rs7534824 0.625 rs61780327 chr1:101449810 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 7.29 0.37 2.23e-12 Refractive astigmatism; LIHC cis rs79149102 0.579 rs7342591 chr15:75306863 C/T cg09165964 chr15:75287851 SCAMP5 0.6 8.24 0.41 3.66e-15 Lung cancer; LIHC cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg07424592 chr7:64974309 NA 0.83 9.5 0.46 3.78e-19 Diabetic kidney disease; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg00463171 chr13:100741364 PCCA 0.54 7.35 0.37 1.5e-12 Hepatitis; LIHC cis rs7772486 0.875 rs2207785 chr6:146332784 T/G cg05347473 chr6:146136440 FBXO30 0.37 6.03 0.31 4.22e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg08556938 chr17:58512855 NA 0.4 6.24 0.32 1.28e-9 Longevity; LIHC cis rs7520050 0.966 rs10749860 chr1:46328210 C/G cg03146154 chr1:46216737 IPP -0.39 -6.47 -0.33 3.4e-10 Red blood cell count;Reticulocyte count; LIHC cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg18252515 chr7:66147081 NA -1.3 -17.23 -0.68 2.36e-48 Diabetic kidney disease; LIHC trans rs8073060 0.586 rs188959 chr17:34021307 C/A cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs7221595 0.778 rs9916457 chr17:3929659 A/C cg11204139 chr17:3907470 NA 0.45 5.73 0.3 2.18e-8 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; LIHC cis rs9467711 0.606 rs28360517 chr6:26602453 A/G cg09904177 chr6:26538194 HMGN4 -0.53 -5.72 -0.3 2.37e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs2795502 1.000 rs3121279 chr10:43378449 T/A cg27426351 chr10:43362370 NA 0.44 5.72 0.3 2.37e-8 Blood protein levels; LIHC cis rs7937682 0.889 rs3017767 chr11:111508098 A/G cg09085632 chr11:111637200 PPP2R1B -1.03 -12.34 -0.56 3.41e-29 Primary sclerosing cholangitis; LIHC trans rs17412740 1.000 rs41343448 chr8:20271413 A/G cg05701478 chr8:19029020 NA 0.44 6.71 0.34 7.96e-11 Preeclampsia; LIHC cis rs801193 0.569 rs2659893 chr7:66199993 G/A cg11764359 chr7:65958608 NA 0.75 12.68 0.57 1.77e-30 Aortic root size; LIHC cis rs10911363 0.659 rs2275676 chr1:183430822 C/G cg09173681 chr1:183549694 NCF2 -0.54 -9.41 -0.45 7.71e-19 Systemic lupus erythematosus; LIHC cis rs9399135 0.967 rs10872427 chr6:135353452 T/C cg22676075 chr6:135203613 NA 0.4 6.52 0.33 2.55e-10 Red blood cell count; LIHC cis rs748404 0.660 rs690367 chr15:43748304 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.46 -7.8 -0.39 7.33e-14 Lung cancer; LIHC cis rs12477438 0.520 rs2632277 chr2:99778985 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.9 13.99 0.6 1.71e-35 Chronic sinus infection; LIHC trans rs875971 0.964 rs778721 chr7:65845397 C/G cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs7044106 0.734 rs1981020 chr9:123388464 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 7.2 0.36 3.75e-12 Hip circumference adjusted for BMI; LIHC cis rs1707322 1.000 rs6429588 chr1:46454058 T/G cg03146154 chr1:46216737 IPP 0.48 7.77 0.39 9.55e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs600806 0.745 rs4246517 chr1:110007636 G/C cg11161837 chr1:110010384 SYPL2 0.45 6.14 0.31 2.32e-9 Intelligence (multi-trait analysis); LIHC cis rs10883723 0.810 rs7090276 chr10:104281239 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Allergic disease (asthma, hay fever or eczema); LIHC cis rs7587476 0.784 rs36086595 chr2:215680293 A/G cg04004882 chr2:215674386 BARD1 0.56 7.83 0.39 6.39e-14 Neuroblastoma; LIHC cis rs1062177 0.756 rs2915826 chr5:151119963 G/A cg00977110 chr5:151150581 G3BP1 -0.56 -7.07 -0.36 8.73e-12 Preschool internalizing problems; LIHC cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg05025164 chr4:1340916 KIAA1530 0.43 6.62 0.34 1.38e-10 Obesity-related traits; LIHC cis rs12893668 0.703 rs34026011 chr14:104050883 G/A cg19000871 chr14:103996768 TRMT61A -0.44 -7.11 -0.36 6.89e-12 Reticulocyte count; LIHC cis rs12478296 1.000 rs57603292 chr2:243028537 G/A cg05760424 chr2:242988095 NA -0.51 -6.86 -0.35 3.31e-11 Obesity-related traits; LIHC cis rs835154 0.845 rs835156 chr5:14875813 C/A cg18064842 chr5:14874549 NA -0.46 -9.49 -0.46 4.04e-19 Blood metabolite levels; LIHC cis rs4803468 0.901 rs3745292 chr19:41888506 A/G cg14132834 chr19:41945861 ATP5SL -0.39 -5.76 -0.3 1.86e-8 Height; LIHC cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg03264133 chr6:25882463 NA 0.85 11.42 0.53 8.53e-26 Blood metabolite levels; LIHC cis rs2645694 0.626 rs2703121 chr4:77822328 C/G cg06046430 chr4:77819534 ANKRD56 0.49 6.56 0.33 1.97e-10 Emphysema distribution in smoking; LIHC cis rs9399135 0.967 rs1041481 chr6:135335063 G/A cg22676075 chr6:135203613 NA 0.4 6.45 0.33 3.88e-10 Red blood cell count; LIHC trans rs2243480 1.000 rs1499613 chr7:65730860 G/A cg10756647 chr7:56101905 PSPH -1.03 -12.48 -0.56 1.05e-29 Diabetic kidney disease; LIHC cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg05368731 chr17:41323189 NBR1 0.72 12.48 0.56 9.96e-30 Menopause (age at onset); LIHC cis rs875971 0.898 rs6977501 chr7:65693342 T/C cg11764359 chr7:65958608 NA -0.89 -15.52 -0.64 1.66e-41 Aortic root size; LIHC cis rs2717559 0.542 rs2717590 chr8:143900712 A/G cg06565975 chr8:143823917 SLURP1 -0.4 -6.58 -0.34 1.82e-10 Urinary tract infection frequency; LIHC cis rs7613875 0.620 rs7624030 chr3:50071279 A/C cg21467203 chr3:49911342 NA 0.52 9.4 0.45 7.87e-19 Body mass index; LIHC cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs9916302 0.904 rs634365 chr17:37436966 C/T cg07936489 chr17:37558343 FBXL20 -0.78 -12.57 -0.56 4.6e-30 Glomerular filtration rate (creatinine); LIHC cis rs2380220 0.872 rs2613529 chr6:95945036 C/T cg04719120 chr6:96025338 MANEA -0.59 -6.21 -0.32 1.53e-9 Behavioural disinhibition (generation interaction); LIHC cis rs4788570 0.566 rs72795864 chr16:71483497 C/G cg06353428 chr16:71660113 MARVELD3 -1.11 -10.1 -0.48 3.73e-21 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg16743903 chr16:89593216 SPG7 -0.3 -5.73 -0.3 2.17e-8 Multiple myeloma (IgH translocation); LIHC cis rs921968 0.541 rs3845835 chr2:219342284 T/C cg02985541 chr2:219472218 PLCD4 -0.42 -6.88 -0.35 2.9100000000000002e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs7959452 0.557 rs899224 chr12:69784774 A/G cg14784868 chr12:69753453 YEATS4 0.94 20.44 0.74 3.16e-61 Blood protein levels; LIHC cis rs6782228 0.585 rs3122175 chr3:128361276 C/T cg16766828 chr3:128327626 NA -0.4 -6.37 -0.33 6.03e-10 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs798554 0.610 rs2251491 chr7:2852835 T/C cg19717773 chr7:2847554 GNA12 -0.42 -7.54 -0.38 4.24e-13 Height; LIHC cis rs2980439 0.525 rs2980508 chr8:8171732 C/T cg15556689 chr8:8085844 FLJ10661 0.45 7.11 0.36 6.77e-12 Neuroticism; LIHC trans rs561341 1.000 rs548957 chr17:30302411 G/A cg20587970 chr11:113659929 NA -1.38 -11.71 -0.53 7.6e-27 Hip circumference adjusted for BMI; LIHC cis rs600626 0.636 rs11236518 chr11:75453066 C/T cg24262691 chr11:75473276 NA 0.39 5.97 0.31 6.06e-9 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs1707322 0.964 rs10437063 chr1:46273666 G/A cg03146154 chr1:46216737 IPP 0.47 7.69 0.38 1.54e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1707322 0.789 rs7540578 chr1:46252144 C/T cg06784218 chr1:46089804 CCDC17 0.39 7.04 0.36 1.04e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6690583 0.623 rs74689037 chr1:85439268 C/T cg22153463 chr1:85462885 MCOLN2 0.52 6.17 0.32 1.93e-9 Serum sulfate level; LIHC cis rs12701220 0.503 rs2949177 chr7:1211518 C/T cg02733842 chr7:1102375 C7orf50 -0.66 -6.9 -0.35 2.55e-11 Bronchopulmonary dysplasia; LIHC cis rs7598759 0.548 rs1584462 chr2:232369798 A/G cg19187155 chr2:232395269 NMUR1 0.58 8.89 0.43 3.47e-17 Noise-induced hearing loss; LIHC cis rs11098499 0.954 rs35091806 chr4:120325529 G/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs936229 0.656 rs12898397 chr15:75130093 T/C cg14664628 chr15:75095509 CSK -0.57 -8.57 -0.42 3.65e-16 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs10056811 0.556 rs55810502 chr5:74380959 A/G cg19683494 chr5:74908142 NA 0.56 7.0 0.35 1.34e-11 Coronary artery disease; LIHC cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.820 rs6829903 chr4:120506884 C/T cg25214090 chr10:38739885 LOC399744 0.57 9.35 0.45 1.15e-18 Corneal astigmatism; LIHC cis rs7713065 0.531 rs2522051 chr5:131797578 C/T cg24060327 chr5:131705240 SLC22A5 -0.45 -6.1 -0.31 2.8e-9 Lung function (FEV1/FVC); LIHC cis rs1983891 1.000 rs9296365 chr6:41535379 A/G cg20194872 chr6:41519635 FOXP4 0.42 6.66 0.34 1.07e-10 Prostate cancer; LIHC cis rs6733011 0.644 rs6542839 chr2:99464530 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.45 6.15 0.32 2.21e-9 Bipolar disorder; LIHC trans rs12310956 0.532 rs6488186 chr12:33974122 G/A cg26384229 chr12:38710491 ALG10B 0.49 6.71 0.34 8.25e-11 Morning vs. evening chronotype; LIHC cis rs6088590 0.965 rs6120730 chr20:33385102 G/C cg06115741 chr20:33292138 TP53INP2 0.58 8.03 0.4 1.59e-14 Coronary artery disease; LIHC cis rs2932538 0.614 rs6537741 chr1:113085175 A/C cg22162597 chr1:113214053 CAPZA1 -0.61 -7.07 -0.36 8.66e-12 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs11971779 0.680 rs6965212 chr7:139026465 G/T cg07862535 chr7:139043722 LUC7L2 0.55 9.3 0.45 1.71e-18 Diisocyanate-induced asthma; LIHC cis rs4638749 0.677 rs6757761 chr2:108834842 T/C cg25838818 chr2:108905173 SULT1C2 -0.4 -6.97 -0.35 1.69e-11 Blood pressure; LIHC cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg10896456 chr17:42255109 ASB16;C17orf65 0.55 10.07 0.48 4.57e-21 Total body bone mineral density; LIHC cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg02290350 chr8:58132656 NA 0.5 10.8 0.5 1.35e-23 Developmental language disorder (linguistic errors); LIHC cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg00091569 chr3:40428383 ENTPD3 0.4 6.83 0.35 4.01e-11 Renal cell carcinoma; LIHC trans rs10740993 0.585 rs7090118 chr10:18459282 C/T cg09391949 chr16:87730651 JPH3 0.43 6.35 0.32 6.89e-10 Primary tooth development (number of teeth);Primary tooth development (time to first tooth eruption); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg20232060 chr3:141457873 RNF7 0.52 7.56 0.38 3.69e-13 Pancreatic cancer; LIHC cis rs6121246 0.909 rs6060821 chr20:30294034 C/T cg13852791 chr20:30311386 BCL2L1 0.97 9.8 0.47 3.82e-20 Mean corpuscular hemoglobin; LIHC cis rs6977660 0.714 rs12386623 chr7:19791875 A/G cg07541023 chr7:19748670 TWISTNB -0.49 -7.47 -0.37 6.64e-13 Thyroid stimulating hormone; LIHC cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg26831259 chr4:1366826 KIAA1530 0.35 5.79 0.3 1.63e-8 Obesity-related traits; LIHC cis rs477895 1.000 rs41294396 chr11:64078581 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.07 0.36 8.61e-12 Mean platelet volume; LIHC cis rs7487075 0.578 rs2897951 chr12:46809206 G/A cg23829395 chr12:46796953 NA 0.36 6.3 0.32 9.14e-10 Itch intensity from mosquito bite; LIHC cis rs17106184 1.000 rs72904723 chr1:51334304 A/G cg07174182 chr1:51127561 FAF1 -0.62 -6.5 -0.33 2.91e-10 Type 2 diabetes; LIHC cis rs798554 0.797 rs798491 chr7:2800521 A/G cg04166393 chr7:2884313 GNA12 0.44 6.18 0.32 1.79e-9 Height; LIHC cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg05564831 chr3:52568323 NT5DC2 0.35 5.79 0.3 1.58e-8 Bipolar disorder; LIHC cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg10560079 chr2:191398806 TMEM194B 0.53 8.22 0.41 4.36e-15 Pulse pressure; LIHC cis rs3806843 0.705 rs2530230 chr5:140088131 G/A cg16179182 chr5:140090404 VTRNA1-1 0.36 5.87 0.3 1.03e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs637571 0.522 rs528736 chr11:65705108 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.53 8.72 0.43 1.2e-16 Eosinophil percentage of white cells; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg21313137 chr20:44462302 SNX21 -0.47 -6.35 -0.32 6.8e-10 Triglycerides; LIHC cis rs1580019 0.961 rs1868777 chr7:32494076 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.65 9.88 0.47 2e-20 Cognitive ability; LIHC trans rs4332037 0.586 rs62442944 chr7:2015047 T/G cg11693508 chr17:37793320 STARD3 0.69 6.98 0.35 1.51e-11 Bipolar disorder; LIHC trans rs877282 0.898 rs11253343 chr10:765117 C/T cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs780096 0.587 rs6760828 chr2:27579231 T/C cg21747090 chr2:27597821 SNX17 -0.47 -7.0 -0.35 1.38e-11 Total body bone mineral density; LIHC cis rs780096 0.565 rs11681351 chr2:27743423 G/A cg05484376 chr2:27715224 FNDC4 0.4 6.58 0.34 1.81e-10 Total body bone mineral density; LIHC cis rs853679 0.517 rs9393894 chr6:28112562 A/G cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs7197653 0.667 rs16957831 chr16:68378341 C/T cg09835421 chr16:68378352 PRMT7 -0.82 -9.86 -0.47 2.42e-20 Magnesium levels; LIHC cis rs7618915 1.000 rs59565798 chr3:52307169 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.41 6.39 0.33 5.56e-10 Bipolar disorder; LIHC cis rs2204008 0.641 rs2387810 chr12:38368875 G/T cg26384229 chr12:38710491 ALG10B 0.59 8.22 0.41 4.31e-15 Bladder cancer; LIHC cis rs722599 0.683 rs11848876 chr14:75224626 C/G cg11812906 chr14:75593930 NEK9 0.41 6.28 0.32 1.01e-9 IgG glycosylation; LIHC cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg12311346 chr5:56204834 C5orf35 -0.58 -7.62 -0.38 2.45e-13 Initial pursuit acceleration; LIHC cis rs7615952 0.800 rs11915699 chr3:125632684 A/G cg05084668 chr3:125655381 ALG1L -0.62 -9.02 -0.44 1.41e-17 Blood pressure (smoking interaction); LIHC cis rs74233809 1.000 rs77602510 chr10:104682602 G/A cg03493300 chr10:104813866 CNNM2 0.46 6.02 0.31 4.57e-9 Birth weight; LIHC trans rs1475622 0.571 rs9601729 chr13:82432073 A/C cg00625354 chr20:45865223 ZMYND8 -0.72 -6.39 -0.33 5.48e-10 Hippocampal volume; LIHC cis rs798554 0.796 rs2533884 chr7:2836848 T/G cg19346786 chr7:2764209 NA -0.46 -6.6 -0.34 1.54e-10 Height; LIHC cis rs8141529 0.719 rs132561 chr22:29351179 C/T cg02153584 chr22:29168773 CCDC117 -0.49 -7.53 -0.38 4.68e-13 Lymphocyte counts; LIHC cis rs11792861 0.926 rs72607171 chr9:111837776 T/C cg13535736 chr9:111863775 C9orf5 -0.38 -5.81 -0.3 1.44e-8 Menarche (age at onset); LIHC cis rs712039 0.652 rs829160 chr17:35763091 T/A cg16670864 chr17:35848621 DUSP14 0.34 5.8 0.3 1.51e-8 Tuberculosis; LIHC cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg00656387 chr3:40428638 ENTPD3 0.43 7.14 0.36 5.7e-12 Renal cell carcinoma; LIHC cis rs67311347 1.000 rs1466236 chr3:40462162 C/T cg13409248 chr3:40428643 ENTPD3 0.42 7.16 0.36 5.01e-12 Renal cell carcinoma; LIHC cis rs644799 0.562 rs669973 chr11:95571839 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.6 8.61 0.42 2.78e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC trans rs9951602 0.512 rs12458828 chr18:76648522 C/T cg02800362 chr5:177631904 HNRNPAB -0.69 -11.0 -0.51 2.77e-24 Obesity-related traits; LIHC trans rs12752401 0.764 rs72725348 chr1:103024349 G/A cg17681729 chr19:740608 PALM 0.56 7.25 0.36 2.83e-12 Resistance to antihypertensive treatment in hypertension; LIHC cis rs838721 0.574 rs11681192 chr2:234258064 A/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.41 5.85 0.3 1.12e-8 Total body bone mineral density; LIHC cis rs11800820 0.557 rs10924755 chr1:246666347 T/A cg16700716 chr1:246684329 NA 0.48 8.11 0.4 9.23e-15 Obesity-related traits; LIHC cis rs10504229 0.679 rs12679920 chr8:58051710 G/T cg02290350 chr8:58132656 NA 0.29 6.16 0.32 2.08e-9 Developmental language disorder (linguistic errors); LIHC cis rs68170813 0.559 rs3823959 chr7:107009379 T/G cg02696742 chr7:106810147 HBP1 -0.5 -5.83 -0.3 1.29e-8 Coronary artery disease; LIHC cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg14983838 chr19:29218262 NA 0.49 7.27 0.37 2.44e-12 Methadone dose in opioid dependence; LIHC cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg16822855 chr3:40428330 ENTPD3 -0.31 -5.71 -0.3 2.43e-8 Renal cell carcinoma; LIHC cis rs400736 0.602 rs4573544 chr1:8165247 C/T cg25007680 chr1:8021821 PARK7 -0.54 -8.24 -0.41 3.81e-15 Response to antidepressants and depression; LIHC cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg05590025 chr7:65112418 INTS4L2 -0.6 -6.67 -0.34 1e-10 Diabetic kidney disease; LIHC cis rs9394841 0.646 rs9471676 chr6:41815192 C/T cg08135965 chr6:41755394 TOMM6 0.45 5.95 0.31 6.46e-9 Mean corpuscular hemoglobin;Red cell distribution width; LIHC cis rs6463523 0.898 rs66892628 chr7:759374 T/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.97 16.13 0.66 6.11e-44 Subjective well-being; LIHC cis rs2051211 1.000 rs2051211 chr3:38559749 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.47 -5.77 -0.3 1.76e-8 QRS duration; LIHC cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg08499158 chr17:42289980 UBTF -0.52 -8.55 -0.42 4.12e-16 Total body bone mineral density; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01989157 chr22:40742702 ADSL 0.4 6.24 0.32 1.33e-9 Pancreatic cancer; LIHC cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg03517284 chr6:25882590 NA 0.6 8.54 0.42 4.42e-16 Blood metabolite levels; LIHC cis rs7903847 0.620 rs61863813 chr10:99112786 T/C cg20016023 chr10:99160130 RRP12 -0.4 -6.13 -0.31 2.42e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg04267008 chr7:1944627 MAD1L1 -0.6 -9.2 -0.45 3.75e-18 Bipolar disorder and schizophrenia; LIHC cis rs7666738 0.546 rs10461174 chr4:98698293 G/A cg05340658 chr4:99064831 C4orf37 0.49 6.38 0.33 5.82e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs1801251 1.000 rs56777991 chr2:233635388 A/C cg25237894 chr2:233734115 C2orf82 0.57 11.18 0.52 6.28e-25 Coronary artery disease; LIHC cis rs9300255 0.509 rs641760 chr12:123518866 T/C cg00376283 chr12:123451042 ABCB9 0.63 8.59 0.42 3.1e-16 Neutrophil percentage of white cells; LIHC cis rs1008375 0.966 rs1860591 chr4:17577329 A/G cg02297831 chr4:17616191 MED28 0.48 7.3 0.37 2.03e-12 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9517320 0.515 rs4772099 chr13:99196121 A/C cg20487152 chr13:99095054 FARP1 -0.38 -6.32 -0.32 8.1e-10 Longevity; LIHC cis rs7258465 1.000 rs7252707 chr19:18612257 G/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.79 -0.39 7.84e-14 Breast cancer; LIHC cis rs7647973 0.731 rs9831648 chr3:49214303 G/T cg07636037 chr3:49044803 WDR6 0.52 6.38 0.33 5.84e-10 Menarche (age at onset); LIHC cis rs6121246 0.567 rs6058197 chr20:30194899 A/G cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg07346676 chr11:60681596 TMEM109 -0.4 -6.11 -0.31 2.65e-9 Immature fraction of reticulocytes; LIHC cis rs7534824 0.625 rs61780328 chr1:101458754 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.65 7.35 0.37 1.49e-12 Refractive astigmatism; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg07959380 chr16:89894648 SPIRE2 0.37 6.1 0.31 2.92e-9 Calcium levels; LIHC cis rs4780401 0.933 rs1592572 chr16:11810382 T/C cg01061890 chr16:11836724 TXNDC11 -0.4 -5.74 -0.3 2.06e-8 Rheumatoid arthritis; LIHC cis rs748404 0.578 rs552701 chr15:43613810 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.58 9.23 0.45 2.9e-18 Lung cancer; LIHC trans rs877282 0.842 rs35117541 chr10:764683 C/T cg22713356 chr15:30763199 NA 1.41 12.28 0.55 5.82e-29 Uric acid levels; LIHC cis rs2286503 0.752 rs59538378 chr7:22877097 G/A cg11367502 chr7:22862612 TOMM7 0.48 8.52 0.42 5.22e-16 Fibrinogen; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg07522190 chr16:28925877 RABEP2 0.37 6.55 0.33 2.09e-10 Longevity; LIHC cis rs12701220 0.522 rs12334290 chr7:1054517 A/G cg00990874 chr7:1149470 C7orf50 -0.54 -8.12 -0.4 8.25e-15 Bronchopulmonary dysplasia; LIHC cis rs10752881 0.905 rs10797830 chr1:183036274 A/T ch.1.3577855R chr1:183094577 LAMC1 0.61 10.58 0.5 8.27e-23 Colorectal cancer; LIHC cis rs11792861 0.890 rs2900481 chr9:111831825 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.82 0.43 6.02e-17 Menarche (age at onset); LIHC cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.45 -8.2 -0.41 4.9e-15 Total body bone mineral density; LIHC cis rs7044106 0.718 rs10616 chr9:123363533 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.54 7.95 0.4 2.68e-14 Hip circumference adjusted for BMI; LIHC cis rs12493885 0.818 rs6800048 chr3:153766181 T/C cg10247383 chr3:153839028 SGEF 0.65 6.09 0.31 3.08e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs875971 1.000 rs778685 chr7:65836176 G/T cg18252515 chr7:66147081 NA -0.41 -5.86 -0.3 1.07e-8 Aortic root size; LIHC cis rs1707322 0.682 rs12041197 chr1:46104464 T/C cg03146154 chr1:46216737 IPP 0.56 9.39 0.45 9e-19 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2274273 0.934 rs2341621 chr14:55726425 C/T cg01864836 chr14:55583639 NA -0.41 -7.86 -0.39 4.89e-14 Protein biomarker; LIHC cis rs738321 0.711 rs5995541 chr22:38553411 C/T cg25457927 chr22:38595422 NA -0.35 -7.78 -0.39 8.95e-14 Breast cancer; LIHC cis rs908922 0.651 rs1572534 chr1:152509689 G/A cg20991723 chr1:152506922 NA 0.51 8.81 0.43 6.35e-17 Hair morphology; LIHC cis rs17401966 0.931 rs1002076 chr1:10438892 G/A cg15208524 chr1:10270712 KIF1B 0.4 5.82 0.3 1.39e-8 Hepatocellular carcinoma; LIHC cis rs506338 0.517 rs490192 chr11:64471369 C/T cg27209729 chr11:64428925 NRXN2 0.33 6.18 0.32 1.8e-9 Body mass index;Urate levels; LIHC cis rs2153535 0.580 rs9505450 chr6:8469902 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs6459788 0.502 rs9692347 chr7:157232659 C/T cg17306686 chr7:157230923 NA 0.43 9.51 0.46 3.57e-19 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg12517452 chr5:52084045 ITGA1;PELO -0.41 -6.19 -0.32 1.68e-9 Body mass index; LIHC trans rs28735056 0.592 rs10853392 chr18:77708781 A/G cg05926928 chr17:57297772 GDPD1 -0.41 -6.05 -0.31 3.79e-9 Schizophrenia; LIHC cis rs1113500 0.702 rs11185262 chr1:108639742 C/T cg06207961 chr1:108661230 NA 0.37 7.31 0.37 1.91e-12 Growth-regulated protein alpha levels; LIHC cis rs892961 0.932 rs3987885 chr17:75414990 A/G cg05865280 chr17:75406074 SEPT9 0.63 12.73 0.57 1.19e-30 Airflow obstruction; LIHC cis rs7223966 1.000 rs9895920 chr17:61852719 T/C cg05941027 chr17:61774174 LIMD2 0.3 6.26 0.32 1.18e-9 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs921968 0.643 rs3931102 chr2:219520405 C/T cg17980119 chr2:219472607 PLCD4 0.34 5.73 0.3 2.18e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg26338869 chr17:61819248 STRADA 0.6 8.75 0.43 9.91e-17 Prudent dietary pattern; LIHC cis rs1580019 0.563 rs13225132 chr7:32800975 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.97 17.37 0.68 6.78e-49 Cognitive ability; LIHC cis rs4319547 0.615 rs2341439 chr12:122848096 C/G cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.16 -0.36 4.82e-12 Body mass index; LIHC cis rs9640161 0.617 rs56019796 chr7:150009226 T/C cg10018233 chr7:150070692 REPIN1 0.49 8.06 0.4 1.3e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs597539 0.652 rs513615 chr11:68705504 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.75 10.31 0.49 7.09e-22 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs7299099 0.966 rs3858607 chr12:94536803 C/G cg10998878 chr12:93964793 SOCS2 -0.41 -5.94 -0.31 7.03e-9 Alopecia areata; LIHC cis rs11758351 0.866 rs77889957 chr6:26207435 A/G cg11342453 chr6:26196699 NA 0.52 5.8 0.3 1.55e-8 Gout;Renal underexcretion gout; LIHC cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg06238570 chr21:40685208 BRWD1 0.6 7.16 0.36 4.86e-12 Cognitive function; LIHC trans rs72960926 1.000 rs72950596 chr6:74921364 C/T cg07247405 chr1:2484626 LOC115110 0.57 6.15 0.32 2.15e-9 Metabolite levels (MHPG); LIHC cis rs780096 0.526 rs13391837 chr2:27649375 A/G cg21248554 chr2:27665150 KRTCAP3 -0.44 -5.93 -0.31 7.32e-9 Total body bone mineral density; LIHC cis rs7091068 0.518 rs1572772 chr10:95432862 A/G cg20715218 chr10:95462985 C10orf4 -0.51 -7.12 -0.36 6.27e-12 Urinary tract infection frequency; LIHC cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg16497277 chr3:49208875 KLHDC8B -0.52 -6.43 -0.33 4.24e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); LIHC cis rs7397814 0.558 rs4764447 chr12:9579109 C/T cg27502298 chr12:9555721 NA 0.87 13.35 0.59 5.12e-33 IgG glycosylation; LIHC cis rs9649213 0.593 rs34534766 chr7:97920871 G/C cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.8 -0.3 1.47e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs1823913 0.599 rs17511410 chr2:192142769 T/C cg12404831 chr2:192114017 MYO1B 0.28 5.73 0.3 2.25e-8 Obesity-related traits; LIHC cis rs2816062 0.786 rs735946 chr1:18901323 T/C cg18795169 chr1:18902165 NA -0.8 -17.71 -0.69 2.87e-50 Urate levels in lean individuals; LIHC cis rs651907 0.535 rs13094753 chr3:101525082 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC trans rs561341 0.556 rs542244 chr17:30307242 T/C cg20587970 chr11:113659929 NA -1.38 -11.63 -0.53 1.45e-26 Hip circumference adjusted for BMI; LIHC cis rs7208859 0.673 rs9913782 chr17:29237384 A/G cg13385521 chr17:29058706 SUZ12P 0.85 8.27 0.41 3.03e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11763147 1 rs11763147 chr7:65326821 C/T cg11987759 chr7:65425863 GUSB 0.39 6.09 0.31 3.01e-9 Corneal structure; LIHC cis rs67311347 1.000 rs2887995 chr3:40409029 C/G cg00656387 chr3:40428638 ENTPD3 0.41 6.87 0.35 2.97e-11 Renal cell carcinoma; LIHC cis rs9902453 0.967 rs7212741 chr17:28322941 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.7 11.49 0.53 4.51e-26 Coffee consumption (cups per day); LIHC cis rs1707322 0.789 rs10789473 chr1:46248131 C/T cg06784218 chr1:46089804 CCDC17 0.39 7.06 0.36 9.24e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs896854 0.738 rs509594 chr8:95967156 C/G cg23172400 chr8:95962367 TP53INP1 0.38 7.64 0.38 2.27e-13 Type 2 diabetes; LIHC cis rs9872999 1 rs9872999 chr3:133457514 C/T cg16262614 chr3:133464971 TF 0.45 10.26 0.49 1.06e-21 Iron status biomarkers; LIHC cis rs4927850 0.752 rs7618864 chr3:195749561 G/A cg01181863 chr3:195395398 SDHAP2 -0.62 -8.83 -0.43 5.55e-17 Pancreatic cancer; LIHC cis rs13191362 1.000 rs67046187 chr6:163068532 C/A cg14584255 chr6:163149320 PACRG;PARK2 0.64 5.74 0.3 2.11e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs2050392 0.590 rs2065723 chr10:30720462 A/T cg25182066 chr10:30743637 MAP3K8 -0.62 -10.02 -0.48 6.71e-21 Inflammatory bowel disease; LIHC trans rs11098499 0.754 rs10518300 chr4:120249499 G/T cg25214090 chr10:38739885 LOC399744 -0.53 -8.42 -0.41 1.08e-15 Corneal astigmatism; LIHC cis rs7312774 0.618 rs7953093 chr12:107334540 G/A cg16260113 chr12:107380972 MTERFD3 0.86 11.06 0.51 1.68e-24 Severe influenza A (H1N1) infection; LIHC cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg05590025 chr7:65112418 INTS4L2 -0.63 -7.05 -0.36 9.75e-12 Diabetic kidney disease; LIHC cis rs10751667 0.643 rs10902245 chr11:953014 C/T cg10932868 chr11:921992 NA -0.37 -7.03 -0.36 1.11e-11 Alzheimer's disease (late onset); LIHC cis rs9790314 0.967 rs9821201 chr3:160996155 G/C cg03342759 chr3:160939853 NMD3 -0.74 -9.13 -0.44 6.06e-18 Morning vs. evening chronotype; LIHC cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg18867708 chr6:26865862 GUSBL1 0.55 8.68 0.42 1.65e-16 Autism spectrum disorder or schizophrenia; LIHC cis rs2742417 0.603 rs2742456 chr3:45767176 C/T cg04837898 chr3:45731254 SACM1L -0.54 -8.98 -0.44 1.89e-17 Response to anti-depressant treatment in major depressive disorder; LIHC cis rs875971 0.522 rs1880556 chr7:65432544 T/C cg14393609 chr7:65229607 NA 0.43 6.25 0.32 1.23e-9 Aortic root size; LIHC cis rs1664789 0.773 rs702637 chr5:53268300 A/G ch.5.1024479R chr5:53302184 ARL15 0.43 6.63 0.34 1.33e-10 Waist circumference adjusted for body mass index; LIHC cis rs3806933 0.522 rs17553936 chr5:110454681 A/G cg04022379 chr5:110408740 TSLP 0.57 9.25 0.45 2.5e-18 Eosinophilic esophagitis; LIHC cis rs6450176 0.638 rs3822497 chr5:53299693 C/G ch.5.1024479R chr5:53302184 ARL15 -0.98 -17.85 -0.69 7.69e-51 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs459571 0.834 rs379417 chr9:136890704 G/A cg13789015 chr9:136890014 NCRNA00094 0.45 8.16 0.4 6.44e-15 Platelet distribution width; LIHC cis rs2760061 0.819 rs708115 chr1:228198046 C/T cg01200585 chr1:228362443 C1orf69 0.4 6.08 0.31 3.13e-9 Diastolic blood pressure; LIHC cis rs17401966 0.931 rs10864448 chr1:10277497 A/T cg15208524 chr1:10270712 KIF1B 0.4 6.01 0.31 4.81e-9 Hepatocellular carcinoma; LIHC cis rs74181299 0.533 rs11678917 chr2:65368214 T/G cg05010058 chr2:65284262 CEP68 -0.36 -5.79 -0.3 1.57e-8 Pulse pressure; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg21548813 chr6:291882 DUSP22 0.52 7.07 0.36 8.65e-12 Menopause (age at onset); LIHC cis rs9457247 0.967 rs433191 chr6:167409662 T/A cg23791538 chr6:167370224 RNASET2 -0.64 -10.91 -0.51 5.74e-24 Crohn's disease; LIHC cis rs9359856 0.564 rs17292768 chr6:90379311 T/C cg13799429 chr6:90582589 CASP8AP2 -0.67 -6.3 -0.32 9.17e-10 Bipolar disorder; LIHC cis rs79387448 0.701 rs10515921 chr2:102981018 T/G cg09003973 chr2:102972529 NA 1.17 9.75 0.47 5.68e-20 Gut microbiota (bacterial taxa); LIHC cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg00149659 chr3:10157352 C3orf10 0.63 6.66 0.34 1.06e-10 Alzheimer's disease; LIHC cis rs769267 0.930 rs4808964 chr19:19603692 A/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.52 -7.86 -0.39 4.95e-14 Tonsillectomy; LIHC cis rs644799 0.965 rs549695 chr11:95617788 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.64 8.8 0.43 7.05e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7296418 0.517 rs73231928 chr12:123724325 T/C cg00376283 chr12:123451042 ABCB9 0.64 10.53 0.49 1.19e-22 Platelet count; LIHC cis rs3733346 0.553 rs6813110 chr4:942660 C/T cg20814179 chr4:940893 TMEM175 0.52 8.81 0.43 6.28e-17 Sjögren's syndrome; LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg13126279 chr21:47581558 C21orf56 -0.47 -7.78 -0.39 8.47e-14 Testicular germ cell tumor; LIHC cis rs7552404 0.883 rs7513363 chr1:76143443 A/G cg03433033 chr1:76189801 ACADM 0.7 10.7 0.5 3.06e-23 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs6570726 0.791 rs12205752 chr6:145896118 A/G cg23711669 chr6:146136114 FBXO30 0.71 12.68 0.57 1.87e-30 Lobe attachment (rater-scored or self-reported); LIHC cis rs6782228 0.606 rs4857861 chr3:128406767 T/C cg16766828 chr3:128327626 NA -0.38 -6.08 -0.31 3.17e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC cis rs11608355 0.515 rs4766606 chr12:109934390 C/G cg05360138 chr12:110035743 NA 0.94 10.75 0.5 1.99e-23 Neuroticism; LIHC cis rs17345786 0.906 rs56171035 chr3:101111108 G/C cg12386194 chr3:101231763 SENP7 0.58 7.6 0.38 2.9e-13 Colonoscopy-negative controls vs population controls; LIHC cis rs17376456 1.000 rs35184505 chr5:93561535 A/G cg25358565 chr5:93447407 FAM172A 1.07 9.89 0.47 1.84e-20 Diabetic retinopathy; LIHC cis rs79149102 0.579 rs3816261 chr15:75336173 T/A cg17294928 chr15:75287854 SCAMP5 -0.54 -6.57 -0.33 1.87e-10 Lung cancer; LIHC cis rs3106136 0.843 rs1426575 chr4:95260069 G/C cg11021082 chr4:95130006 SMARCAD1 0.41 7.28 0.37 2.34e-12 Capecitabine sensitivity; LIHC cis rs72781680 0.898 rs72788218 chr2:24090435 C/T cg08917208 chr2:24149416 ATAD2B 0.86 8.43 0.41 9.98e-16 Lymphocyte counts; LIHC cis rs523522 0.962 rs10849758 chr12:120971149 C/T cg12219531 chr12:120966889 COQ5 0.67 13.37 0.59 4.19e-33 High light scatter reticulocyte count; LIHC cis rs875971 0.862 rs6978028 chr7:65886300 G/C cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg18252515 chr7:66147081 NA -1.29 -17.09 -0.68 9.12e-48 Diabetic kidney disease; LIHC cis rs10744422 1.000 rs7959441 chr12:123363825 C/T cg25930673 chr12:123319894 HIP1R -0.86 -10.54 -0.5 1.15e-22 Schizophrenia; LIHC cis rs7520050 0.966 rs10789475 chr1:46304177 C/G cg03146154 chr1:46216737 IPP -0.37 -5.92 -0.3 8e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg15691649 chr6:25882328 NA 0.51 7.39 0.37 1.12e-12 Blood metabolite levels; LIHC cis rs12477438 0.871 rs62156364 chr2:99695097 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.01 -12.57 -0.56 4.61e-30 Chronic sinus infection; LIHC trans rs8113308 0.810 rs73582180 chr19:52446537 G/A cg14959425 chr7:20447707 ITGB8 -0.47 -6.1 -0.31 2.87e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs6430585 0.528 rs309119 chr2:136710372 T/C cg07169764 chr2:136633963 MCM6 0.95 14.38 0.61 5.13e-37 Corneal structure; LIHC cis rs9910055 0.593 rs58392387 chr17:42297889 A/G cg08499158 chr17:42289980 UBTF -0.5 -8.55 -0.42 4.12e-16 Total body bone mineral density; LIHC cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg00656387 chr3:40428638 ENTPD3 0.41 6.66 0.34 1.06e-10 Renal cell carcinoma; LIHC cis rs3770081 1.000 rs2303340 chr2:86333193 A/G cg01119172 chr2:86362222 SNORD94;PTCD3 0.42 6.13 0.31 2.42e-9 Facial emotion recognition (sad faces); LIHC cis rs7208859 0.623 rs216439 chr17:28927884 T/C cg14067834 chr17:29058358 SUZ12P 0.68 6.66 0.34 1.12e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg21724239 chr8:58056113 NA 0.48 6.28 0.32 1.01e-9 Developmental language disorder (linguistic errors); LIHC trans rs6897795 0.680 rs9329133 chr5:177609540 C/T cg19598605 chr2:70056955 GMCL1 -0.57 -7.39 -0.37 1.11e-12 Plateletcrit; LIHC cis rs17685 0.753 rs10251863 chr7:75790192 T/C cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.33 -0.32 7.84e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9303401 0.659 rs12602808 chr17:56698420 A/G cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs3859192 0.537 rs12309 chr17:38175462 C/T cg17344932 chr17:38183730 MED24;SNORD124 0.79 15.82 0.65 1.11e-42 White blood cell count; LIHC cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.02 0.44 1.38e-17 Platelet count; LIHC cis rs853679 0.517 rs4713146 chr6:28111536 A/T cg16479474 chr6:28041457 NA 0.46 6.45 0.33 3.81e-10 Depression; LIHC cis rs12701220 0.689 rs12701824 chr7:1102364 G/A cg02733842 chr7:1102375 C7orf50 -0.77 -8.35 -0.41 1.71e-15 Bronchopulmonary dysplasia; LIHC cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg24531977 chr5:56204891 C5orf35 -0.67 -9.57 -0.46 2.15e-19 Initial pursuit acceleration; LIHC cis rs8017423 0.967 rs2282030 chr14:90730265 G/A cg04374321 chr14:90722782 PSMC1 0.78 15.26 0.64 1.75e-40 Mortality in heart failure; LIHC cis rs9420 0.961 rs71484461 chr11:57488890 G/A cg19752551 chr11:57585705 CTNND1 -0.53 -7.39 -0.37 1.16e-12 Schizophrenia; LIHC cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg11062466 chr8:58055876 NA 0.49 6.4 0.33 5.04e-10 Developmental language disorder (linguistic errors); LIHC cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg22520471 chr17:61851767 DDX42;CCDC47 -0.5 -7.58 -0.38 3.23e-13 Prudent dietary pattern; LIHC cis rs3823572 0.564 rs2953623 chr7:133659410 C/G cg03336402 chr7:133662267 EXOC4 -0.47 -5.82 -0.3 1.38e-8 Intelligence (multi-trait analysis); LIHC cis rs847649 0.961 rs7456502 chr7:102596022 C/A cg18108683 chr7:102477205 FBXL13 0.48 7.54 0.38 4.18e-13 Morning vs. evening chronotype; LIHC cis rs9486715 1.000 rs9373985 chr6:97063522 C/G cg06623918 chr6:96969491 KIAA0776 -0.85 -14.12 -0.61 5.42e-36 Headache; LIHC cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg16434002 chr17:42200994 HDAC5 -0.53 -7.8 -0.39 7.78e-14 Total body bone mineral density; LIHC cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg05590025 chr7:65112418 INTS4L2 -0.63 -6.89 -0.35 2.62e-11 Diabetic kidney disease; LIHC cis rs7312933 0.533 rs17551006 chr12:42848738 G/C cg01256987 chr12:42539512 GXYLT1 -0.35 -5.83 -0.3 1.31e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs1005277 0.589 rs2749624 chr10:38529865 A/G cg03665457 chr10:38645376 HSD17B7P2 -0.43 -6.17 -0.32 1.96e-9 Extrinsic epigenetic age acceleration; LIHC cis rs780096 0.526 rs1260341 chr2:27663215 T/A cg11618577 chr2:27665543 KRTCAP3 -0.44 -6.01 -0.31 4.82e-9 Total body bone mineral density; LIHC cis rs9858542 0.953 rs12330269 chr3:49513910 G/A cg03060546 chr3:49711283 APEH -0.49 -6.78 -0.34 5.14e-11 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs4665809 0.887 rs6546716 chr2:26263836 A/G cg04944784 chr2:26401820 FAM59B -0.71 -8.92 -0.43 2.85e-17 Gut microbiome composition (summer); LIHC cis rs3731827 0.511 rs14976 chr2:85818886 C/T cg16865965 chr2:85811662 VAMP5 0.42 5.94 0.31 7.04e-9 Prostate cancer; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg04167819 chr14:73395839 DCAF4 0.4 6.1 0.31 2.88e-9 Bilirubin levels; LIHC cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.12 10.68 0.5 3.47e-23 Platelet count; LIHC cis rs9902453 0.904 rs4598962 chr17:28293948 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 13.57 0.59 7.09e-34 Coffee consumption (cups per day); LIHC cis rs28829049 0.536 rs12405382 chr1:19548981 C/T cg13387374 chr1:19411106 UBR4 0.42 6.19 0.32 1.74e-9 QRS duration in Tripanosoma cruzi seropositivity; LIHC cis rs7312933 0.558 rs11181507 chr12:42844763 T/A cg01256987 chr12:42539512 GXYLT1 -0.35 -5.82 -0.3 1.35e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs2933343 0.700 rs789239 chr3:128633808 T/C cg24203234 chr3:128598194 ACAD9 0.45 6.29 0.32 9.77e-10 IgG glycosylation; LIHC cis rs1707322 1.000 rs10890365 chr1:46359348 C/T cg03146154 chr1:46216737 IPP 0.47 7.57 0.38 3.42e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg23131131 chr22:24373011 LOC391322 -0.5 -6.63 -0.34 1.33e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs2242116 0.900 rs1001284 chr3:46933960 C/G cg23352942 chr3:46931381 PTH1R -0.32 -8.37 -0.41 1.5e-15 Birth weight; LIHC cis rs10744422 0.528 rs6489245 chr12:123360151 G/A cg07706471 chr12:123319906 HIP1R -0.59 -7.21 -0.36 3.61e-12 Schizophrenia; LIHC trans rs1814175 0.645 rs1851857 chr11:49855589 A/C cg18944383 chr4:111397179 ENPEP 0.27 6.96 0.35 1.78e-11 Height; LIHC cis rs875971 0.617 rs810400 chr7:66022889 G/C cg18876405 chr7:65276391 NA -0.44 -7.78 -0.39 8.74e-14 Aortic root size; LIHC cis rs9420 0.961 rs79260745 chr11:57612960 T/C cg19752551 chr11:57585705 CTNND1 -0.49 -6.8 -0.35 4.67e-11 Schizophrenia; LIHC trans rs61931739 0.517 rs11513277 chr12:34074799 G/T cg26384229 chr12:38710491 ALG10B 0.49 6.83 0.35 4.01e-11 Morning vs. evening chronotype; LIHC cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg20607798 chr8:58055168 NA 0.59 6.9 0.35 2.57e-11 Developmental language disorder (linguistic errors); LIHC cis rs9611519 0.894 rs4821990 chr22:41438710 A/C cg06634786 chr22:41940651 POLR3H -0.53 -5.98 -0.31 5.71e-9 Neuroticism; LIHC cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg05564831 chr3:52568323 NT5DC2 0.36 5.93 0.31 7.45e-9 Electroencephalogram traits; LIHC cis rs9308433 0.553 rs9308435 chr1:214500166 C/T cg06198575 chr1:214491504 SMYD2 0.53 5.79 0.3 1.57e-8 IgG glycosylation; LIHC cis rs992157 0.735 rs2271541 chr2:219082119 G/T cg00012203 chr2:219082015 ARPC2 0.92 16.51 0.67 1.98e-45 Colorectal cancer; LIHC cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg12463550 chr7:65579703 CRCP 0.67 7.02 0.36 1.17e-11 Diabetic kidney disease; LIHC cis rs912057 0.601 rs1294411 chr6:6739034 T/C cg06612196 chr6:6737390 NA 0.55 10.4 0.49 3.52e-22 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs881375 1.000 rs881375 chr9:123652898 T/C cg14580859 chr9:123691850 NA 0.38 6.55 0.33 2.08e-10 Rheumatoid arthritis; LIHC cis rs769267 0.930 rs892021 chr19:19613480 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.98 0.4 2.19e-14 Tonsillectomy; LIHC cis rs2404602 0.647 rs34103231 chr15:76912690 A/G cg23625390 chr15:77176239 SCAPER -0.53 -8.7 -0.43 1.4e-16 Blood metabolite levels; LIHC cis rs9611565 0.568 rs5758441 chr22:42132888 C/A cg06634786 chr22:41940651 POLR3H 0.57 6.25 0.32 1.23e-9 Vitiligo; LIHC cis rs910316 0.935 rs11159119 chr14:75636967 C/T cg11812906 chr14:75593930 NEK9 -0.72 -14.08 -0.61 7.77e-36 Height; LIHC cis rs7044106 0.500 rs56725168 chr9:123492576 T/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.6 9.29 0.45 1.81e-18 Hip circumference adjusted for BMI; LIHC cis rs644799 0.965 rs3016295 chr11:95554311 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.16 0.68 4.59e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs56104184 0.668 rs73063523 chr19:49408943 T/C cg15549821 chr19:49342101 PLEKHA4 -0.65 -6.07 -0.31 3.36e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs7582720 1.000 rs114110842 chr2:203823400 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs380904 0.926 rs7842979 chr8:144601896 T/G cg10810860 chr8:144639591 GSDMD -0.44 -5.8 -0.3 1.52e-8 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs9513627 0.831 rs7319727 chr13:100125541 A/T cg25919922 chr13:100150906 NA -0.76 -6.66 -0.34 1.07e-10 Obesity-related traits; LIHC cis rs7552404 1.000 rs11163924 chr1:76132070 A/C cg22875332 chr1:76189707 ACADM -0.47 -6.91 -0.35 2.45e-11 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7258465 0.965 rs7256534 chr19:18586791 C/T cg10790698 chr19:18539756 SSBP4 -0.35 -7.43 -0.37 8.68e-13 Breast cancer; LIHC cis rs9300255 0.543 rs1260294 chr12:123560289 T/C cg00376283 chr12:123451042 ABCB9 -0.61 -5.83 -0.3 1.25e-8 Neutrophil percentage of white cells; LIHC cis rs249954 0.559 rs35586 chr16:23677006 A/G cg01460202 chr16:23706506 ERN2 0.36 6.0 0.31 5.08e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs11030122 0.645 rs11493482 chr11:4034772 A/G cg18678763 chr11:4115507 RRM1 -0.58 -8.56 -0.42 3.78e-16 Mean platelet volume;Platelet distribution width; LIHC trans rs1814175 0.647 rs61306292 chr11:49856040 G/C cg15704280 chr7:45808275 SEPT13 -1.03 -23.58 -0.79 1.11e-73 Height; LIHC cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg02951883 chr7:2050386 MAD1L1 -0.61 -8.91 -0.43 3e-17 Bipolar disorder and schizophrenia; LIHC cis rs2836974 0.644 rs1882779 chr21:40690938 T/C cg06238570 chr21:40685208 BRWD1 -0.54 -8.83 -0.43 5.4e-17 Cognitive function; LIHC cis rs9583531 0.600 rs6492305 chr13:111361400 C/T cg24331049 chr13:111365604 ING1 0.78 13.14 0.58 3.32e-32 Coronary artery disease; LIHC cis rs4450131 0.618 rs3781452 chr10:126355129 A/G cg20435097 chr10:126320824 FAM53B 0.59 10.99 0.51 2.84e-24 White blood cell count (basophil); LIHC cis rs8062405 1.000 rs12443881 chr16:28841777 C/T cg07451762 chr16:28383216 NA 0.36 6.66 0.34 1.08e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs13382862 0.862 rs340595 chr2:20889714 A/G cg10687131 chr2:20871002 GDF7 -0.37 -7.11 -0.36 6.91e-12 Abdominal aortic aneurysm; LIHC cis rs6448317 0.954 rs13139649 chr4:24922007 C/A cg21108841 chr4:24914750 CCDC149 -0.5 -6.32 -0.32 8.24e-10 Heschl's gyrus morphology; LIHC cis rs7534824 0.625 rs6692186 chr1:101470217 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.68 6.74 0.34 6.76e-11 Refractive astigmatism; LIHC cis rs8067545 0.611 rs11653630 chr17:20189046 C/T cg13482628 chr17:19912719 NA -0.41 -6.77 -0.34 5.62e-11 Schizophrenia; LIHC cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg00091569 chr3:40428383 ENTPD3 0.39 6.74 0.34 6.6e-11 Renal cell carcinoma; LIHC cis rs1003719 0.762 rs9975361 chr21:38450025 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.26 0.55 6.97e-29 Eye color traits; LIHC cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg06656553 chr16:89960601 TCF25 -0.47 -6.01 -0.31 4.87e-9 Skin colour saturation; LIHC cis rs8017423 0.935 rs4904661 chr14:90729332 T/C cg04374321 chr14:90722782 PSMC1 0.78 15.17 0.63 4.07e-40 Mortality in heart failure; LIHC cis rs9868809 0.505 rs11708786 chr3:48752654 C/T cg07636037 chr3:49044803 WDR6 -0.64 -7.1 -0.36 7.08e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs10911232 0.507 rs4483371 chr1:182988352 G/A ch.1.3577855R chr1:183094577 LAMC1 0.59 10.35 0.49 5.1e-22 Hypertriglyceridemia; LIHC cis rs9916302 0.851 rs9904919 chr17:37556431 G/C cg07936489 chr17:37558343 FBXL20 0.84 13.57 0.59 7.17e-34 Glomerular filtration rate (creatinine); LIHC cis rs7772486 0.846 rs9373482 chr6:146363123 A/C cg23711669 chr6:146136114 FBXO30 0.67 11.96 0.54 8.61e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs2033711 0.783 rs8113810 chr19:58932106 A/G cg00825309 chr19:58991885 ZNF446 -0.63 -9.78 -0.47 4.29e-20 Uric acid clearance; LIHC cis rs3814244 0.528 rs2906859 chr12:68396135 C/T cg15249341 chr12:68405565 NA -0.34 -6.9 -0.35 2.52e-11 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs4713118 0.513 rs149941 chr6:28001033 T/C cg16479474 chr6:28041457 NA 0.38 6.24 0.32 1.29e-9 Parkinson's disease; LIHC cis rs7552404 1.000 rs7518038 chr1:76154430 G/A cg03433033 chr1:76189801 ACADM 0.66 9.31 0.45 1.65e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4979906 1.000 rs68092325 chr10:79446719 T/A cg07817648 chr10:79422355 NA -0.3 -6.4 -0.33 5.15e-10 Mortality in heart failure; LIHC cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg08645402 chr16:4508243 NA 0.4 7.35 0.37 1.52e-12 Schizophrenia; LIHC cis rs8180040 0.701 rs11130111 chr3:47009805 C/T cg16586182 chr3:47516702 SCAP -0.47 -8.5 -0.42 6.1e-16 Colorectal cancer; LIHC cis rs7769051 0.711 rs9493435 chr6:133088205 A/G cg22852734 chr6:133119734 C6orf192 0.77 7.48 0.38 6.2e-13 Type 2 diabetes nephropathy; LIHC cis rs4466137 0.830 rs6886695 chr5:82994293 T/A cg16102102 chr5:83017553 HAPLN1 -0.59 -8.59 -0.42 3.12e-16 Prostate cancer; LIHC cis rs7589728 0.748 rs35051888 chr2:88482258 G/A cg14558114 chr2:88469736 THNSL2 0.65 6.85 0.35 3.53e-11 Plasma clusterin levels; LIHC cis rs7769051 1.000 rs9493444 chr6:133125320 C/G cg22852734 chr6:133119734 C6orf192 0.96 9.44 0.45 6.11e-19 Type 2 diabetes nephropathy; LIHC cis rs12477438 0.798 rs10202452 chr2:99569409 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.8 -10.19 -0.48 1.85e-21 Chronic sinus infection; LIHC trans rs61931739 0.500 rs9705909 chr12:34576419 G/C cg26384229 chr12:38710491 ALG10B 0.81 9.89 0.47 1.82e-20 Morning vs. evening chronotype; LIHC cis rs875971 0.830 rs6976714 chr7:65891461 G/A cg11764359 chr7:65958608 NA 0.83 14.41 0.61 4e-37 Aortic root size; LIHC cis rs1552244 0.554 rs3732965 chr3:10048760 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC cis rs7208859 0.673 rs11654914 chr17:29229424 C/G cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2455799 0.613 rs13078485 chr3:15883236 T/C cg12698662 chr3:15914712 MIR563 -0.4 -7.41 -0.37 9.96e-13 Mean platelet volume; LIHC cis rs67478160 0.595 rs12889993 chr14:104274294 A/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.57 0.56 4.76e-30 Schizophrenia; LIHC cis rs6582630 0.555 rs7305352 chr12:38473800 T/C cg26384229 chr12:38710491 ALG10B 0.92 11.63 0.53 1.47e-26 Drug-induced liver injury (flucloxacillin); LIHC cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg23131131 chr22:24373011 LOC391322 -0.55 -7.58 -0.38 3.38e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7312774 0.748 rs7295619 chr12:107316934 T/A cg16260113 chr12:107380972 MTERFD3 0.79 10.19 0.48 1.77e-21 Severe influenza A (H1N1) infection; LIHC cis rs769267 0.929 rs2965180 chr19:19491973 T/C cg03709012 chr19:19516395 GATAD2A -1.01 -18.1 -0.7 7.56e-52 Tonsillectomy; LIHC cis rs8180040 0.593 rs4018905 chr3:47138170 A/G cg16586182 chr3:47516702 SCAP -0.48 -8.69 -0.43 1.55e-16 Colorectal cancer; LIHC cis rs9303401 0.659 rs12600349 chr17:57054245 A/G cg10487724 chr17:56770010 TEX14;RAD51C -0.98 -13.64 -0.59 4.09e-34 Cognitive test performance; LIHC cis rs4845570 0.831 rs11588634 chr1:151780686 T/A cg07092448 chr1:151763213 TDRKH -0.67 -6.87 -0.35 2.97e-11 Coronary artery disease; LIHC cis rs2304069 0.909 rs10038824 chr5:149369776 G/A cg22760475 chr5:149380129 HMGXB3;TIGD6 -0.92 -11.55 -0.53 2.73e-26 HIV-1 control; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg08943361 chr16:56462172 NA 0.37 6.22 0.32 1.48e-9 Immature fraction of reticulocytes; LIHC cis rs611744 0.967 rs603571 chr8:109213893 A/C cg18478394 chr8:109455254 TTC35 0.39 6.84 0.35 3.7e-11 Dupuytren's disease; LIHC cis rs2235642 0.785 rs1057983 chr16:1660274 A/G cg03034668 chr16:1723424 CRAMP1L -0.38 -6.91 -0.35 2.39e-11 Coronary artery disease; LIHC cis rs7312933 0.645 rs12049942 chr12:42587052 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 7.66 0.38 1.95e-13 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs7208859 0.673 rs60020217 chr17:29185054 G/A cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs12220238 1.000 rs11000941 chr10:76018301 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.67 6.78 0.34 5.43e-11 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg00091569 chr3:40428383 ENTPD3 0.39 6.74 0.34 6.75e-11 Renal cell carcinoma; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg14585611 chr2:175260420 CIR1;SCRN3 -0.4 -6.19 -0.32 1.69e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs992157 1.000 rs2168704 chr2:219142492 G/A cg00012203 chr2:219082015 ARPC2 0.86 14.25 0.61 1.76e-36 Colorectal cancer; LIHC cis rs17253792 0.822 rs13379342 chr14:56050452 A/G cg01858014 chr14:56050164 KTN1 -0.76 -8.12 -0.4 8.74e-15 Putamen volume; LIHC cis rs3809566 0.963 rs3809565 chr15:63333619 A/G cg21584241 chr15:63341463 TPM1 -0.38 -5.74 -0.3 2.14e-8 Platelet count; LIHC cis rs13108904 0.934 rs35201724 chr4:1310717 C/G cg13395646 chr4:1353034 KIAA1530 -0.68 -9.52 -0.46 3.23e-19 Obesity-related traits; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10106725 chr4:3071494 NA -0.47 -7.33 -0.37 1.63e-12 Lung function (FEV1/FVC); LIHC cis rs7617773 0.743 rs11715876 chr3:48377922 G/A cg11946769 chr3:48343235 NME6 0.93 11.81 0.54 3.03e-27 Coronary artery disease; LIHC cis rs910316 0.737 rs175510 chr14:75524839 G/A cg08847533 chr14:75593920 NEK9 -0.9 -18.8 -0.71 1.14e-54 Height; LIHC cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1499614 1.000 rs2707828 chr7:66171377 G/A cg18252515 chr7:66147081 NA -1.34 -18.97 -0.72 2.55e-55 Gout; LIHC cis rs365132 0.840 rs58400555 chr5:176454081 A/T cg16309518 chr5:176445507 NA -0.59 -11.44 -0.53 6.84e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs8067354 0.645 rs2645486 chr17:57885901 T/A cg13753209 chr17:57696993 CLTC 0.74 11.66 0.53 1.11e-26 Hemoglobin concentration; LIHC trans rs116095464 0.558 rs28558836 chr5:285748 C/G cg00938859 chr5:1591904 SDHAP3 0.52 6.43 0.33 4.29e-10 Breast cancer; LIHC cis rs35110281 0.712 rs8133523 chr21:45062403 A/G cg01579765 chr21:45077557 HSF2BP -0.35 -6.56 -0.33 2.01e-10 Mean corpuscular volume; LIHC cis rs4727027 0.727 rs1568944 chr7:148873497 A/T cg23583168 chr7:148888333 NA -0.73 -9.02 -0.44 1.33e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs8180040 0.764 rs4082155 chr3:47125385 G/A cg16586182 chr3:47516702 SCAP -0.51 -9.23 -0.45 2.81e-18 Colorectal cancer; LIHC cis rs2404602 0.684 rs4886816 chr15:76874707 A/C cg03037974 chr15:76606532 NA -0.61 -10.21 -0.48 1.55e-21 Blood metabolite levels; LIHC cis rs9674544 0.646 rs6504594 chr17:47142697 C/A cg07075026 chr17:47091521 IGF2BP1 -0.43 -5.91 -0.3 8.3e-9 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg01685246 chr16:30538016 ZNF768 0.41 6.56 0.33 2.01e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs7224737 0.673 rs11079035 chr17:40289012 C/T cg20291162 chr17:40259547 DHX58 -0.42 -6.0 -0.31 5.13e-9 Fibrinogen levels; LIHC cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg11952622 chr19:58962976 ZNF324B 0.49 7.24 0.36 3.08e-12 Uric acid clearance; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06713199 chr3:28390809 AZI2 0.4 6.21 0.32 1.56e-9 Pancreatic cancer; LIHC cis rs11048434 0.736 rs7301381 chr12:9123932 T/C cg04155231 chr12:9217510 LOC144571 0.31 5.81 0.3 1.42e-8 Sjögren's syndrome; LIHC cis rs67460515 1.000 rs67460515 chr3:161068566 T/C cg17135325 chr3:160939158 NMD3 0.52 7.54 0.38 4.16e-13 Parkinson's disease; LIHC cis rs6973256 0.604 rs6975134 chr7:133531432 T/C cg10665199 chr7:133106180 EXOC4 0.34 5.77 0.3 1.82e-8 Intelligence (multi-trait analysis); LIHC cis rs2236918 0.687 rs2797601 chr1:242029249 C/G cg17736920 chr1:242011382 EXO1 0.41 6.04 0.31 3.99e-9 Menopause (age at onset); LIHC cis rs16866061 1.000 rs10933068 chr2:225418360 G/A cg12698349 chr2:225449008 CUL3 0.8 14.2 0.61 2.66e-36 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs7618501 1.000 rs11130221 chr3:49819102 C/G cg21659725 chr3:3221576 CRBN 0.99 19.77 0.73 1.43e-58 Intelligence (multi-trait analysis); LIHC cis rs3806843 0.900 rs2337983 chr5:140136808 G/A cg19875535 chr5:140030758 IK -0.36 -5.89 -0.3 9.44e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7617773 0.780 rs36075665 chr3:48343087 C/T cg11946769 chr3:48343235 NME6 0.91 11.5 0.53 4.09e-26 Coronary artery disease; LIHC cis rs4853012 0.887 rs6737314 chr2:74339586 A/G cg05890377 chr2:74357713 NA 0.63 12.31 0.55 4.3e-29 Gestational age at birth (maternal effect); LIHC cis rs9534288 0.762 rs3934247 chr13:46549137 C/T cg15192986 chr13:46630673 CPB2 -0.55 -8.4 -0.41 1.18e-15 Blood protein levels; LIHC cis rs2842992 0.830 rs2758312 chr6:160153452 G/A cg11366901 chr6:160182831 ACAT2 0.96 16.28 0.66 1.58e-44 Age-related macular degeneration (geographic atrophy); LIHC trans rs4843747 0.671 rs28679286 chr16:88106307 C/T cg26811252 chr16:29126840 RRN3P2 0.42 6.87 0.35 3.01e-11 Menopause (age at onset); LIHC cis rs6701037 1.000 rs7514749 chr1:175122123 A/G cg00321850 chr1:175162397 KIAA0040 -0.38 -5.89 -0.3 9.28e-9 Alcohol dependence; LIHC cis rs12022452 0.556 rs11208298 chr1:40978878 A/G cg25568243 chr1:40974465 DEM1 0.45 6.09 0.31 2.95e-9 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs6594499 1.000 rs1438673 chr5:110467499 C/T cg04022379 chr5:110408740 TSLP 0.4 6.21 0.32 1.57e-9 Allergic disease (asthma, hay fever or eczema); LIHC cis rs769267 0.930 rs7254927 chr19:19404786 C/G cg21559469 chr19:19431446 KIAA0892;SF4 0.41 5.74 0.3 2.09e-8 Tonsillectomy; LIHC cis rs2153535 0.542 rs915353 chr6:8440370 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.86e-16 Motion sickness; LIHC cis rs769267 0.965 rs2916068 chr19:19516433 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.54 8.21 0.41 4.72e-15 Tonsillectomy; LIHC cis rs807029 0.533 rs12571302 chr10:102742763 C/A cg17130504 chr10:102756923 LZTS2 0.56 7.77 0.39 9.27e-14 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs17685 0.753 rs1637039 chr7:75693009 C/T cg01364799 chr7:75623366 TMEM120A -0.51 -7.81 -0.39 6.99e-14 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7238033 0.560 rs8083653 chr18:43315027 T/C cg20610511 chr18:43302872 SLC14A1 0.4 6.64 0.34 1.24e-10 Bladder cancer; LIHC cis rs7264396 0.563 rs6060566 chr20:34288226 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.61 -8.5 -0.42 6.02e-16 Total cholesterol levels; LIHC cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg17372223 chr3:52568218 NT5DC2 0.36 5.87 0.3 1.06e-8 Electroencephalogram traits; LIHC cis rs6499255 0.904 rs9929720 chr16:69557096 C/T cg15192750 chr16:69999425 NA -0.45 -7.1 -0.36 7.42e-12 IgE levels; LIHC cis rs7551222 0.646 rs10900590 chr1:204451086 C/T cg20240347 chr1:204465584 NA -0.33 -6.81 -0.35 4.38e-11 Schizophrenia; LIHC cis rs72781680 0.898 rs72782117 chr2:24026921 G/A cg08917208 chr2:24149416 ATAD2B 0.96 8.09 0.4 1.02e-14 Lymphocyte counts; LIHC cis rs11577318 0.853 rs4333841 chr1:26631927 T/C cg18121669 chr1:26560928 CCDC21 0.5 7.99 0.4 2.04e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs2599510 0.811 rs2754523 chr2:32837110 A/G cg02381751 chr2:32503542 YIPF4 0.49 6.84 0.35 3.57e-11 Interleukin-18 levels; LIHC cis rs67981189 0.593 rs8006046 chr14:71498991 A/G cg15816911 chr14:71606274 NA 0.42 6.84 0.35 3.7e-11 Schizophrenia; LIHC cis rs7903847 0.642 rs11189177 chr10:99141663 C/T cg20016023 chr10:99160130 RRP12 -0.42 -6.59 -0.34 1.63e-10 Granulocyte percentage of myeloid white cells; LIHC trans rs459571 0.920 rs455073 chr9:136909141 G/C cg09836344 chr4:1243392 C4orf42;CTBP1 -0.58 -8.95 -0.44 2.23e-17 Platelet distribution width; LIHC cis rs2153535 0.580 rs6927589 chr6:8456632 A/G cg21535247 chr6:8435926 SLC35B3 -0.64 -8.53 -0.42 4.8e-16 Motion sickness; LIHC cis rs12368653 0.641 rs12826708 chr12:58058373 G/A cg12615879 chr12:58013172 SLC26A10 0.36 6.91 0.35 2.34e-11 Multiple sclerosis; LIHC cis rs7582180 0.614 rs9973737 chr2:100942296 T/C cg14675211 chr2:100938903 LONRF2 0.54 8.05 0.4 1.34e-14 Intelligence (multi-trait analysis); LIHC cis rs10801727 0.582 rs9428044 chr1:90005159 A/C cg15422784 chr1:90023713 LRRC8B -0.44 -6.05 -0.31 3.77e-9 Parental extreme longevity (95 years and older); LIHC cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.75 0.62 1.8e-38 Prudent dietary pattern; LIHC cis rs3768617 0.782 rs10752893 chr1:183046261 C/T ch.1.3577855R chr1:183094577 LAMC1 0.48 7.65 0.38 2.08e-13 Fuchs's corneal dystrophy; LIHC cis rs317689 0.690 rs317646 chr12:69657145 A/G cg14784868 chr12:69753453 YEATS4 -0.54 -7.67 -0.38 1.77e-13 Response to diuretic therapy; LIHC cis rs8053891 0.756 rs35259348 chr16:72003952 G/C cg01557791 chr16:72042693 DHODH -0.5 -7.18 -0.36 4.4e-12 Coronary artery disease; LIHC cis rs8103278 1.000 rs9807819 chr19:46239598 C/T cg02376097 chr19:46275166 DMPK -0.48 -7.71 -0.38 1.34e-13 Coronary artery disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25750404 chr12:6579648 VAMP1 0.41 6.28 0.32 1.04e-9 Cognitive function; LIHC cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.67 9.48 0.46 4.32e-19 Lymphocyte counts; LIHC cis rs311392 1.000 rs311392 chr8:55084782 A/G cg20636351 chr8:55087400 NA -0.34 -6.87 -0.35 3.04e-11 Pelvic organ prolapse (moderate/severe); LIHC cis rs1664789 1.000 rs1628025 chr5:53282682 A/G ch.5.1024479R chr5:53302184 ARL15 -0.48 -7.64 -0.38 2.15e-13 Waist circumference adjusted for body mass index; LIHC cis rs10540 1.000 rs35811812 chr11:498442 G/A cg03576123 chr11:487126 PTDSS2 -1.12 -8.45 -0.42 8.23e-16 Body mass index; LIHC cis rs8062405 1.000 rs62036617 chr16:28827498 T/C cg00204512 chr16:28754710 NA 0.35 6.49 0.33 3e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7534824 0.625 rs12569251 chr1:101372040 C/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.72 6.96 0.35 1.76e-11 Refractive astigmatism; LIHC cis rs1670533 0.932 rs10902753 chr4:1056223 G/A cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.38e-17 Recombination rate (females); LIHC cis rs8062405 1.000 rs72793811 chr16:28839392 G/A cg07451762 chr16:28383216 NA 0.34 6.36 0.33 6.48e-10 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23334365 chr11:67806337 TCIRG1 0.44 6.93 0.35 2.14e-11 Lung function (FEV1/FVC); LIHC trans rs61931739 0.534 rs2625897 chr12:34064295 G/A cg26384229 chr12:38710491 ALG10B 0.43 6.04 0.31 3.94e-9 Morning vs. evening chronotype; LIHC cis rs8180040 1.000 rs295461 chr3:47368010 T/C cg02527881 chr3:46936655 PTH1R -0.3 -5.87 -0.3 1.04e-8 Colorectal cancer; LIHC cis rs2438150 1 rs2438150 chr5:122199196 C/T cg18764291 chr5:122110994 SNX2 0.36 6.07 0.31 3.47e-9 Plateletcrit; LIHC cis rs72781680 0.898 rs12622290 chr2:23979894 C/G cg08917208 chr2:24149416 ATAD2B 0.83 7.5 0.38 5.52e-13 Lymphocyte counts; LIHC cis rs7617773 0.780 rs71323396 chr3:48374734 T/G cg11946769 chr3:48343235 NME6 0.91 11.78 0.54 3.91e-27 Coronary artery disease; LIHC cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg22907277 chr7:1156413 C7orf50 0.39 5.84 0.3 1.23e-8 Longevity;Endometriosis; LIHC cis rs6723226 0.803 rs387780 chr2:32502495 T/C cg02381751 chr2:32503542 YIPF4 0.79 11.96 0.54 8.58e-28 Intelligence (multi-trait analysis); LIHC cis rs801193 0.569 rs11772819 chr7:66217970 T/C cg18252515 chr7:66147081 NA -0.47 -6.86 -0.35 3.21e-11 Aortic root size; LIHC cis rs7772486 0.875 rs9403763 chr6:146357655 A/G cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 5.8e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs140364877 1 rs140364877 chr7:1885178 C/T cg20295408 chr7:1910781 MAD1L1 -0.48 -6.98 -0.35 1.51e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs79839061 0.610 rs9994159 chr4:891150 C/T cg07828340 chr4:882639 GAK 0.85 7.43 0.37 8.5e-13 Intelligence (multi-trait analysis); LIHC cis rs10751667 0.643 rs7942693 chr11:957832 G/A ch.11.42038R chr11:967971 AP2A2 0.56 10.09 0.48 4.1e-21 Alzheimer's disease (late onset); LIHC cis rs4668356 0.892 rs1863679 chr2:172017906 C/T cg13882835 chr2:172017928 TLK1 0.46 6.23 0.32 1.38e-9 Cognitive performance; LIHC cis rs9790314 0.638 rs6441339 chr3:160619683 T/G cg03342759 chr3:160939853 NMD3 0.54 7.08 0.36 8.12e-12 Morning vs. evening chronotype; LIHC cis rs9581857 0.685 rs9579084 chr13:28028201 A/G cg22138327 chr13:27999177 GTF3A -0.7 -6.21 -0.32 1.53e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); LIHC trans rs9926296 0.656 rs11861084 chr16:89875710 G/T cg13698153 chr12:118541722 VSIG10 -0.58 -6.23 -0.32 1.38e-9 Vitiligo; LIHC cis rs11122272 0.735 rs2486735 chr1:231521778 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -10.63 -0.5 5.36e-23 Hemoglobin concentration; LIHC cis rs9309473 0.607 rs6716776 chr2:73587713 T/C cg20560298 chr2:73613845 ALMS1 -0.44 -6.86 -0.35 3.22e-11 Metabolite levels; LIHC cis rs72781680 0.898 rs17762651 chr2:24115922 A/G cg08917208 chr2:24149416 ATAD2B 0.84 7.73 0.39 1.21e-13 Lymphocyte counts; LIHC trans rs1814175 0.645 rs11040671 chr11:49958776 G/A cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC trans rs4566357 0.576 rs10187255 chr2:227913442 T/A cg16088116 chr21:44841560 SIK1 -0.4 -6.23 -0.32 1.4e-9 Coronary artery disease; LIHC trans rs7613875 0.600 rs2624826 chr3:50155468 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.42 -6.37 -0.33 6.08e-10 Body mass index; LIHC cis rs600806 0.821 rs10127790 chr1:109891133 C/T cg23091122 chr1:110024289 SYPL2 -0.48 -6.54 -0.33 2.3e-10 Intelligence (multi-trait analysis); LIHC cis rs6762 0.748 rs7928935 chr11:839127 G/A cg07691484 chr11:842764 TSPAN4;POLR2L -0.74 -9.34 -0.45 1.28e-18 Mean platelet volume; LIHC cis rs3096299 0.967 rs2911257 chr16:89484134 C/G cg08392591 chr16:89556376 ANKRD11 0.39 5.78 0.3 1.71e-8 Multiple myeloma (IgH translocation); LIHC cis rs798554 0.591 rs1713913 chr7:2895627 C/T cg13628971 chr7:2884303 GNA12 0.44 7.73 0.39 1.22e-13 Height; LIHC cis rs2758596 1.000 rs2842866 chr1:156159721 G/A cg25208724 chr1:156163844 SLC25A44 0.78 8.57 0.42 3.68e-16 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs921968 0.573 rs684776 chr2:219324016 T/C cg18887096 chr2:219472410 PLCD4 0.37 5.78 0.3 1.64e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs1843834 0.539 rs3912999 chr2:225390089 C/T cg22455342 chr2:225449267 CUL3 0.58 8.48 0.42 6.76e-16 IgE levels in asthmatics (D.p. specific); LIHC cis rs1371867 0.846 rs1660327 chr8:101292206 A/C cg06636551 chr8:101224915 SPAG1 -0.5 -9.05 -0.44 1.13e-17 Atrioventricular conduction; LIHC cis rs7520050 0.966 rs2486447 chr1:46545724 G/A cg01431908 chr1:46668882 C1orf190;POMGNT1 0.39 5.9 0.3 8.87e-9 Red blood cell count;Reticulocyte count; LIHC cis rs12048904 0.930 rs11166529 chr1:101333733 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.53 8.37 0.41 1.45e-15 Multiple sclerosis; LIHC trans rs3820928 0.605 rs4281898 chr2:227855493 A/C cg16088116 chr21:44841560 SIK1 -0.39 -6.08 -0.31 3.12e-9 Pulmonary function; LIHC cis rs17854409 0.764 rs16983293 chr20:61479056 A/G cg07645718 chr20:61493192 TCFL5 0.78 6.12 0.31 2.56e-9 Obesity-related traits; LIHC cis rs3892630 0.824 rs35654350 chr19:33223766 T/C cg22980127 chr19:33182716 NUDT19 1.0 11.72 0.54 6.83e-27 Red blood cell traits; LIHC cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg05564831 chr3:52568323 NT5DC2 0.38 6.16 0.32 2.09e-9 Bipolar disorder; LIHC cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg23758822 chr17:41437982 NA 0.91 16.69 0.67 3.58e-46 Menopause (age at onset); LIHC cis rs2979489 0.773 rs10954993 chr8:30303388 C/T cg26383811 chr8:30366931 RBPMS 0.73 11.97 0.54 8.05e-28 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg06481639 chr22:41940642 POLR3H -0.61 -5.78 -0.3 1.65e-8 Vitiligo; LIHC cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -10.41 -0.49 3.04e-22 Platelet count; LIHC cis rs9814567 1.000 rs4974484 chr3:134219019 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.69 -12.38 -0.56 2.41e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10464366 0.544 rs34866559 chr7:39166071 G/A cg20302533 chr7:39170763 POU6F2 0.38 6.95 0.35 1.8e-11 IgG glycosylation; LIHC cis rs11792861 0.926 rs7470160 chr9:111844246 C/A cg13535736 chr9:111863775 C9orf5 -0.38 -5.73 -0.3 2.21e-8 Menarche (age at onset); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25508545 chr19:49467065 FTL 0.4 6.47 0.33 3.34e-10 Cognitive function; LIHC cis rs12478296 0.901 rs9653611 chr2:243006956 C/G cg18898632 chr2:242989856 NA -0.47 -6.52 -0.33 2.58e-10 Obesity-related traits; LIHC trans rs1814175 0.817 rs1988416 chr11:49932324 G/A cg03929089 chr4:120376271 NA -0.89 -18.34 -0.7 8.22e-53 Height; LIHC cis rs921968 0.643 rs552882 chr2:219401726 G/A cg02985541 chr2:219472218 PLCD4 0.45 8.68 0.42 1.62e-16 Mean corpuscular hemoglobin concentration; LIHC trans rs7618501 1.000 rs11716575 chr3:49744890 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.73e-40 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg12751644 chr20:60527061 NA -0.35 -5.85 -0.3 1.15e-8 Body mass index; LIHC cis rs10838687 0.800 rs3729802 chr11:47354068 G/A cg26139080 chr11:47293733 MADD -0.42 -5.81 -0.3 1.45e-8 Proinsulin levels; LIHC cis rs11031096 0.655 rs56172516 chr11:4182004 G/T cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.46e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1348850 0.958 rs1545364 chr2:178462882 G/T cg02961200 chr2:178257176 LOC100130691;AGPS 0.76 11.39 0.52 1.08e-25 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7616330 0.836 rs17008114 chr3:71045000 A/C cg01511742 chr3:71112437 FOXP1 -0.44 -6.16 -0.32 2.08e-9 QT interval; LIHC cis rs10744422 1.000 rs1532835 chr12:123330665 G/A cg22842854 chr12:123319900 HIP1R -0.72 -9.43 -0.45 6.2800000000000005e-19 Schizophrenia; LIHC cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg20607798 chr8:58055168 NA 0.69 7.83 0.39 6.13e-14 Developmental language disorder (linguistic errors); LIHC cis rs7937682 0.575 rs7930208 chr11:111741463 T/C cg09085632 chr11:111637200 PPP2R1B 0.96 13.8 0.6 9.84e-35 Primary sclerosing cholangitis; LIHC cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg02503808 chr4:7069936 GRPEL1 0.79 11.86 0.54 2.1e-27 Monocyte percentage of white cells; LIHC cis rs7005606 0.532 rs6981660 chr8:32298476 A/G cg24995904 chr8:32462945 NRG1 0.39 5.78 0.3 1.71e-8 Hirschsprung disease; LIHC cis rs11583043 1.000 rs6675353 chr1:101459625 A/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.51 6.26 0.32 1.17e-9 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs7107174 1.000 rs2510040 chr11:77944548 T/A cg02023728 chr11:77925099 USP35 0.48 8.82 0.43 6.1e-17 Testicular germ cell tumor; LIHC cis rs7072216 0.727 rs6584199 chr10:100169983 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.37 -0.33 6.08e-10 Metabolite levels; LIHC cis rs875971 0.862 rs6460290 chr7:65809106 G/A cg18252515 chr7:66147081 NA 0.44 6.37 0.33 5.98e-10 Aortic root size; LIHC cis rs8017423 0.967 rs7146640 chr14:90720114 C/T cg14092571 chr14:90743983 NA 0.41 6.57 0.33 1.91e-10 Mortality in heart failure; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20923575 chr17:56596273 MTMR4 0.42 6.58 0.34 1.8e-10 Cognitive function; LIHC cis rs908922 0.651 rs564107 chr1:152519295 C/T cg20991723 chr1:152506922 NA 0.54 9.07 0.44 9.25e-18 Hair morphology; LIHC cis rs1552244 0.882 rs34706481 chr3:10004123 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.76 10.06 0.48 4.94e-21 Alzheimer's disease; LIHC cis rs7572733 0.534 rs1401092 chr2:198792320 C/A cg03934865 chr2:198174659 NA -0.47 -6.84 -0.35 3.6e-11 Dermatomyositis; LIHC cis rs9916302 0.768 rs11078900 chr17:37614641 C/T cg00129232 chr17:37814104 STARD3 -0.42 -6.81 -0.35 4.45e-11 Glomerular filtration rate (creatinine); LIHC trans rs9858542 0.953 rs1873625 chr3:49666964 C/A cg21659725 chr3:3221576 CRBN -0.59 -6.61 -0.34 1.5e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.67 0.38 1.75e-13 Prudent dietary pattern; LIHC cis rs9916302 0.904 rs9905432 chr17:37555918 C/A cg03013999 chr17:37608204 MED1 -0.35 -5.81 -0.3 1.4e-8 Glomerular filtration rate (creatinine); LIHC cis rs10771431 0.713 rs17794353 chr12:9361783 C/T cg08997352 chr12:9597637 DDX12 0.52 8.02 0.4 1.69e-14 Breast size; LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.73 12.72 0.57 1.27e-30 Prudent dietary pattern; LIHC cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg08859206 chr1:53392774 SCP2 0.46 7.28 0.37 2.38e-12 Monocyte count; LIHC cis rs12549902 1.000 rs12550613 chr8:41510260 G/C cg21772509 chr8:41503840 NKX6-3 0.42 6.85 0.35 3.41e-11 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs6088813 1.000 rs6087703 chr20:33996433 T/C cg14752227 chr20:34000481 UQCC -0.41 -5.9 -0.3 8.6e-9 Height; LIHC cis rs2932538 0.961 rs6537746 chr1:113163529 C/T cg22162597 chr1:113214053 CAPZA1 -0.71 -11.03 -0.51 2.07e-24 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs644799 0.710 rs12273579 chr11:95524421 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.77 13.25 0.58 1.27e-32 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs16858210 0.837 rs1879254 chr3:183609471 C/T cg25686905 chr3:183603175 PARL -0.49 -9.09 -0.44 8.39e-18 Menopause (age at onset); LIHC cis rs12579753 1.000 rs7963577 chr12:82174115 T/C cg07988820 chr12:82153109 PPFIA2 -0.49 -6.07 -0.31 3.34e-9 Resting heart rate; LIHC trans rs9951602 1.000 rs9949784 chr18:76649994 A/G cg02800362 chr5:177631904 HNRNPAB 0.58 7.92 0.39 3.41e-14 Obesity-related traits; LIHC cis rs2574704 0.651 rs2616552 chr3:11666798 G/T cg15876825 chr3:11651881 VGLL4 0.41 6.15 0.32 2.19e-9 Body mass index; LIHC cis rs4975616 0.804 rs459961 chr5:1337106 T/A cg26373071 chr5:1325741 CLPTM1L 0.36 5.78 0.3 1.66e-8 Lung cancer; LIHC cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg20887711 chr4:1340912 KIAA1530 0.78 12.56 0.56 5.33e-30 Longevity; LIHC cis rs7264396 0.563 rs6058322 chr20:34367277 G/A cg04508476 chr20:34239394 CPNE1;RBM12 0.56 7.72 0.39 1.29e-13 Total cholesterol levels; LIHC cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg08067268 chr2:26466485 HADHB;HADHA -0.45 -6.79 -0.34 4.85e-11 Gut microbiome composition (summer); LIHC cis rs8064299 0.655 rs734232 chr17:72765731 C/T cg25054828 chr17:72772726 NAT9;TMEM104 0.62 9.88 0.47 1.98e-20 Monocyte count; LIHC cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 8.74 0.43 1.09e-16 Colonoscopy-negative controls vs population controls; LIHC cis rs796364 1.000 rs281783 chr2:200751582 G/A cg25936922 chr2:200820526 C2orf60;C2orf47 0.72 8.41 0.41 1.1e-15 Schizophrenia; LIHC cis rs9368481 0.524 rs9393768 chr6:26885619 A/G cg12292205 chr6:26970375 C6orf41 0.43 7.13 0.36 6.03e-12 Autism spectrum disorder or schizophrenia; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16717988 chr16:89715857 CHMP1A 0.45 6.81 0.35 4.53e-11 Longevity; LIHC trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg07332563 chr6:291687 DUSP22 -0.51 -7.27 -0.37 2.53e-12 Menopause (age at onset); LIHC cis rs4407350 1.000 rs5765725 chr22:44921706 A/C cg26276947 chr22:44892394 LDOC1L 0.35 6.42 0.33 4.52e-10 Intelligence (multi-trait analysis); LIHC cis rs9902453 0.726 rs4795523 chr17:28176314 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 14.47 0.62 2.31e-37 Coffee consumption (cups per day); LIHC cis rs7937682 0.737 rs682239 chr11:111425105 A/G cg09085632 chr11:111637200 PPP2R1B 0.76 9.57 0.46 2.17e-19 Primary sclerosing cholangitis; LIHC cis rs11030122 0.702 rs4910866 chr11:3950554 A/T cg18678763 chr11:4115507 RRM1 -0.58 -8.59 -0.42 3.21e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs769267 0.566 rs7249692 chr19:19670688 T/C cg03709012 chr19:19516395 GATAD2A -0.85 -12.38 -0.56 2.42e-29 Tonsillectomy; LIHC cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg13395646 chr4:1353034 KIAA1530 -0.61 -8.98 -0.44 1.89e-17 Obesity-related traits; LIHC cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg11502198 chr6:26597334 ABT1 0.64 10.1 0.48 3.55e-21 Intelligence (multi-trait analysis); LIHC cis rs798554 1.000 rs798540 chr7:2764130 G/A cg13628971 chr7:2884303 GNA12 0.53 7.69 0.38 1.53e-13 Height; LIHC cis rs6952808 0.531 rs3779002 chr7:2183219 C/T cg04267008 chr7:1944627 MAD1L1 -0.49 -7.57 -0.38 3.59e-13 Bipolar disorder and schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03157738 chr19:11308118 KANK2 0.38 6.14 0.32 2.3e-9 Cognitive function; LIHC cis rs477692 0.699 rs471357 chr10:131389373 C/G cg05714579 chr10:131428358 MGMT 0.43 7.1 0.36 7.31e-12 Response to temozolomide; LIHC cis rs2303745 0.589 rs11086065 chr19:17395003 A/G cg02221750 chr19:17393354 ANKLE1 -0.42 -5.97 -0.31 5.96e-9 Systemic lupus erythematosus; LIHC cis rs910316 0.726 rs12882664 chr14:75446778 C/T cg08847533 chr14:75593920 NEK9 0.88 17.84 0.69 8.88e-51 Height; LIHC cis rs8084351 0.599 rs11082970 chr18:50681121 G/T cg24270629 chr18:50823537 DCC -0.46 -6.9 -0.35 2.49e-11 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg21724239 chr8:58056113 NA 0.57 7.62 0.38 2.58e-13 Developmental language disorder (linguistic errors); LIHC cis rs10838687 0.736 rs830083 chr11:47254051 G/C cg25783544 chr11:47291846 MADD -0.47 -5.87 -0.3 1.05e-8 Proinsulin levels; LIHC cis rs2153535 0.580 rs9406161 chr6:8466144 G/T cg07606381 chr6:8435919 SLC35B3 0.81 12.22 0.55 9.52e-29 Motion sickness; LIHC cis rs8084351 0.557 rs1821075 chr18:50760660 G/A cg24270629 chr18:50823537 DCC -0.5 -7.18 -0.36 4.27e-12 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs12824058 0.831 rs12300308 chr12:130813825 G/A cg24838063 chr12:130822603 PIWIL1 0.66 9.79 0.47 4.02e-20 Menopause (age at onset); LIHC cis rs66887589 0.616 rs11098498 chr4:120187119 T/C cg09307838 chr4:120376055 NA 0.53 7.82 0.39 6.49e-14 Diastolic blood pressure; LIHC cis rs6426558 0.537 rs7512409 chr1:227484038 A/G cg10327440 chr1:227177885 CDC42BPA -0.41 -6.4 -0.33 5.05e-10 Neutrophil percentage of white cells; LIHC cis rs66573146 0.831 rs67665838 chr4:7064870 G/A cg26116260 chr4:7069785 GRPEL1 -0.99 -12.08 -0.55 3.19e-28 Granulocyte percentage of myeloid white cells; LIHC cis rs2625529 0.607 rs2912231 chr15:72567957 G/T cg16672083 chr15:72433130 SENP8 -0.3 -5.74 -0.3 2.12e-8 Red blood cell count; LIHC cis rs4728302 0.934 rs2971963 chr7:133641505 A/G cg03336402 chr7:133662267 EXOC4 0.38 5.75 0.3 2.03e-8 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs11971779 0.688 rs1862880 chr7:139020100 T/C cg07862535 chr7:139043722 LUC7L2 0.66 11.2 0.52 5.23e-25 Diisocyanate-induced asthma; LIHC cis rs9640161 0.711 rs55881542 chr7:150025734 G/A cg12556325 chr7:150026731 C7orf29;LRRC61 -0.54 -8.97 -0.44 1.92e-17 Blood protein levels;Circulating chemerin levels; LIHC cis rs2549003 1.000 rs2070726 chr5:131821738 C/A cg21138405 chr5:131827807 IRF1 0.37 9.68 0.46 9.75e-20 Asthma (sex interaction); LIHC cis rs9549367 0.865 rs3861721 chr13:113906308 C/T cg18105134 chr13:113819100 PROZ -0.68 -11.64 -0.53 1.29e-26 Platelet distribution width; LIHC cis rs9733 0.519 rs7521898 chr1:150707596 G/A cg18016565 chr1:150552671 MCL1 0.59 11.39 0.52 1.06e-25 Tonsillectomy; LIHC cis rs7914558 0.966 rs3758543 chr10:104944744 C/G cg15744005 chr10:104629667 AS3MT -0.38 -8.55 -0.42 4.22e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs3213545 0.700 rs10849829 chr12:121470256 A/G cg15155738 chr12:121454335 C12orf43 -0.44 -6.36 -0.33 6.53e-10 Subjective well-being;Cardiovascular disease risk factors; LIHC cis rs72781680 0.898 rs17462670 chr2:24026579 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.68 0.38 1.68e-13 Lymphocyte counts; LIHC cis rs735396 0.965 rs2257962 chr12:121445808 T/C cg25281562 chr12:121454272 C12orf43 0.33 5.79 0.3 1.62e-8 N-glycan levels; LIHC cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg04727924 chr7:799746 HEATR2 0.41 6.25 0.32 1.25e-9 Perceived unattractiveness to mosquitoes; LIHC cis rs9649465 0.967 rs3757505 chr7:123391641 C/T cg03229431 chr7:123269106 ASB15 -0.38 -8.04 -0.4 1.5e-14 Migraine; LIHC cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg06108461 chr20:60628389 TAF4 -0.9 -13.95 -0.6 2.59e-35 Body mass index; LIHC cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg22800045 chr5:56110881 MAP3K1 0.66 8.42 0.41 1.05e-15 Initial pursuit acceleration; LIHC cis rs909341 0.818 rs2750483 chr20:62345470 A/G cg03999872 chr20:62272968 STMN3 -0.45 -6.77 -0.34 5.56e-11 Atopic dermatitis; LIHC cis rs9486719 1.000 rs11153023 chr6:96968525 C/T cg06623918 chr6:96969491 KIAA0776 -0.72 -6.93 -0.35 2.05e-11 Migraine;Coronary artery disease; LIHC cis rs798554 0.757 rs2533878 chr7:2878707 A/G cg19717773 chr7:2847554 GNA12 0.43 6.6 0.34 1.6e-10 Height; LIHC cis rs4268898 0.722 rs6723257 chr2:24391129 A/G cg06627628 chr2:24431161 ITSN2 0.45 6.36 0.33 6.64e-10 Asthma; LIHC cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg00750074 chr16:89608354 SPG7 -0.49 -7.7 -0.38 1.44e-13 Multiple myeloma (IgH translocation); LIHC cis rs2857078 0.720 rs9901595 chr17:42305699 G/A cg10896456 chr17:42255109 ASB16;C17orf65 0.41 7.29 0.37 2.14e-12 Red cell distribution width;Reticulocyte count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg03306564 chr11:64902099 SYVN1 0.4 6.47 0.33 3.48e-10 Cognitive function; LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg02993280 chr1:107599747 PRMT6 0.61 9.9 0.47 1.7e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4555082 0.834 rs4412909 chr14:105759226 T/C cg06808227 chr14:105710500 BRF1 -0.5 -6.46 -0.33 3.56e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs780096 0.506 rs2303369 chr2:27715416 C/T cg17158414 chr2:27665306 KRTCAP3 -0.42 -5.76 -0.3 1.83e-8 Total body bone mineral density; LIHC cis rs736408 0.812 rs9324 chr3:52825585 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.46 7.44 0.37 7.97e-13 Bipolar disorder; LIHC cis rs11663156 0.804 rs12604606 chr18:50901856 A/G cg24270629 chr18:50823537 DCC -0.52 -7.0 -0.35 1.38e-11 Intelligence (multi-trait analysis); LIHC trans rs561341 1.000 rs72825712 chr17:30316119 A/T cg20587970 chr11:113659929 NA -1.46 -11.98 -0.54 7.67e-28 Hip circumference adjusted for BMI; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg01185801 chr11:65265397 MALAT1 0.43 6.8 0.35 4.76e-11 Cognitive function; LIHC cis rs3741151 1.000 rs75007932 chr11:73080336 G/A cg17517138 chr11:73019481 ARHGEF17 0.9 6.5 0.33 2.81e-10 GIP levels in response to oral glucose tolerance test (120 minutes); LIHC cis rs7582720 0.945 rs72936860 chr2:203783484 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs910316 0.591 rs7157158 chr14:75457238 A/G cg11812906 chr14:75593930 NEK9 0.74 13.85 0.6 6.36e-35 Height; LIHC cis rs8016982 0.674 rs3815953 chr14:81685482 G/A cg01989461 chr14:81687754 GTF2A1 0.7 14.59 0.62 8.35e-38 Schizophrenia; LIHC cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg08219700 chr8:58056026 NA 0.51 6.7 0.34 8.62e-11 Developmental language disorder (linguistic errors); LIHC cis rs6942756 0.955 rs68187585 chr7:129002211 T/C cg02491457 chr7:128862824 NA -0.63 -9.35 -0.45 1.18e-18 White matter hyperintensity burden; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.0 24.39 0.8 7.99e-77 Prudent dietary pattern; LIHC cis rs7772486 0.805 rs4896831 chr6:145959481 T/C cg05347473 chr6:146136440 FBXO30 0.33 5.74 0.3 2.08e-8 Lobe attachment (rater-scored or self-reported); LIHC trans rs916888 0.610 rs199529 chr17:44837217 A/C cg22968622 chr17:43663579 NA 1.1 12.24 0.55 8.25e-29 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC trans rs8002861 0.935 rs9525865 chr13:44459647 A/T cg17145862 chr1:211918768 LPGAT1 0.67 13.28 0.58 9.75e-33 Leprosy; LIHC cis rs8020095 0.571 rs2281676 chr14:67638455 C/G cg03487553 chr14:67822707 ATP6V1D 0.33 5.81 0.3 1.45e-8 Depression (quantitative trait); LIHC cis rs2842992 0.672 rs7738253 chr6:160193917 G/T cg19482086 chr6:160211437 TCP1;MRPL18 0.67 11.43 0.53 7.64e-26 Age-related macular degeneration (geographic atrophy); LIHC cis rs7408868 1.000 rs10420466 chr19:15261371 G/T cg02272795 chr19:15279244 NOTCH3 -0.32 -5.76 -0.3 1.84e-8 Pulse pressure; LIHC cis rs921968 0.643 rs485765 chr2:219480804 C/G cg18887096 chr2:219472410 PLCD4 0.34 6.0 0.31 4.93e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7586673 0.866 rs747003 chr2:161916409 C/T cg21518248 chr2:162101506 NA -0.38 -5.72 -0.3 2.27e-8 Intelligence (multi-trait analysis); LIHC cis rs929354 0.772 rs6459738 chr7:156998532 T/G cg05182265 chr7:156933206 UBE3C -0.32 -5.94 -0.31 6.88e-9 Body mass index; LIHC cis rs4820539 0.641 rs5759602 chr22:23489362 C/T cg21100191 chr22:23484243 RTDR1 -0.81 -9.13 -0.44 6.04e-18 Bone mineral density; LIHC cis rs7617773 0.817 rs6796490 chr3:48237104 A/C cg11946769 chr3:48343235 NME6 0.61 8.41 0.41 1.09e-15 Coronary artery disease; LIHC cis rs72829446 0.530 rs11869864 chr17:7407766 C/A cg02795151 chr17:7402630 POLR2A 0.55 6.39 0.33 5.45e-10 Androgen levels; LIHC cis rs801193 0.904 rs4718403 chr7:66242729 C/G cg11764359 chr7:65958608 NA 0.71 10.6 0.5 6.78e-23 Aortic root size; LIHC cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs3770081 1.000 rs17618001 chr2:86289303 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.84 -8.59 -0.42 3.03e-16 Facial emotion recognition (sad faces); LIHC cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.92 -10.52 -0.49 1.3e-22 Platelet count; LIHC cis rs9309711 0.666 rs6723101 chr2:3484443 T/C cg10845886 chr2:3471009 TTC15 -0.44 -8.34 -0.41 1.87e-15 Neurofibrillary tangles; LIHC cis rs3768617 0.565 rs10752901 chr1:183089327 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.4 0.49 3.49e-22 Fuchs's corneal dystrophy; LIHC cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.81 0.3 1.41e-8 Menopause (age at onset); LIHC cis rs1059312 0.932 rs4760589 chr12:129284382 T/C cg09035930 chr12:129282057 SLC15A4 0.68 12.97 0.57 1.41e-31 Systemic lupus erythematosus; LIHC cis rs651907 0.557 rs7629753 chr3:101371922 C/T cg03334568 chr3:101395165 ZBTB11;LOC100009676 0.45 6.6 0.34 1.59e-10 Colorectal cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg00170564 chr12:107714106 BTBD11 0.49 7.23 0.36 3.21e-12 Pancreatic cancer; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg00091569 chr3:40428383 ENTPD3 -0.39 -6.61 -0.34 1.51e-10 Renal cell carcinoma; LIHC cis rs7249142 0.573 rs2238668 chr19:19282597 A/G cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.35 -5.91 -0.3 8.13e-9 IgG glycosylation; LIHC cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg21664854 chr7:1097933 C7orf50;GPR146 0.78 6.08 0.31 3.13e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs4474465 0.850 rs4565922 chr11:78260699 A/G cg27205649 chr11:78285834 NARS2 0.42 6.39 0.33 5.44e-10 Alzheimer's disease (survival time); LIHC cis rs6546550 0.935 rs2168115 chr2:70034793 A/G cg02498382 chr2:70120550 SNRNP27 -0.42 -6.83 -0.35 3.88e-11 Prevalent atrial fibrillation; LIHC cis rs17152411 1.000 rs41303609 chr10:126670613 G/T cg07906193 chr10:126599966 NA 0.5 7.89 0.39 4e-14 Height; LIHC cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg13126279 chr21:47581558 C21orf56 -0.38 -6.02 -0.31 4.62e-9 Testicular germ cell tumor; LIHC cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg25894440 chr7:65020034 NA 0.48 5.83 0.3 1.27e-8 Diabetic kidney disease; LIHC cis rs10751667 0.600 rs11246376 chr11:999622 C/T ch.11.42038R chr11:967971 AP2A2 0.58 10.89 0.51 6.69e-24 Alzheimer's disease (late onset); LIHC trans rs1671400 1.000 rs919586 chr8:13174671 A/G cg00420450 chr8:22132641 PIWIL2 0.62 6.47 0.33 3.3e-10 Obesity-related traits; LIHC trans rs2352908 0.786 rs8006912 chr14:49427753 T/C cg16568472 chr20:3190600 ITPA -0.46 -6.08 -0.31 3.27e-9 Social communication problems; LIHC cis rs2304069 0.826 rs245076 chr5:149350648 C/T cg12661370 chr5:149340060 SLC26A2 0.48 6.49 0.33 2.96e-10 HIV-1 control; LIHC cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg13770153 chr20:60521292 NA -0.35 -7.08 -0.36 8.46e-12 Body mass index; LIHC cis rs422249 0.512 rs174578 chr11:61605499 T/A cg27386326 chr11:61587980 NA 0.69 14.92 0.63 4.15e-39 Trans fatty acid levels; LIHC cis rs9467160 0.532 rs2744565 chr6:24458461 G/T cg20631270 chr6:24437470 GPLD1 -0.38 -5.74 -0.3 2.12e-8 Liver enzyme levels; LIHC cis rs2228479 0.850 rs17232630 chr16:89851179 C/T cg06558623 chr16:89946397 TCF25 0.84 11.03 0.51 2.02e-24 Skin colour saturation; LIHC cis rs9649213 0.593 rs7789380 chr7:97956180 G/A cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.92 -0.3 7.72e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs1997103 1.000 rs10270618 chr7:55396712 T/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.24e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs8060686 0.641 rs8044014 chr16:68209872 T/C cg05110241 chr16:68378359 PRMT7 -0.51 -6.03 -0.31 4.14e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs8017423 0.647 rs4904679 chr14:90821801 C/T cg04374321 chr14:90722782 PSMC1 -0.49 -7.27 -0.37 2.46e-12 Mortality in heart failure; LIHC cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg21724239 chr8:58056113 NA 0.64 7.32 0.37 1.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg21747090 chr2:27597821 SNX17 -0.42 -6.22 -0.32 1.49e-9 Total body bone mineral density; LIHC cis rs2153535 0.580 rs7453115 chr6:8447261 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.65 0.53 1.21e-26 Motion sickness; LIHC cis rs700651 0.789 rs1147169 chr2:198901395 C/T cg00792783 chr2:198669748 PLCL1 -0.44 -6.19 -0.32 1.72e-9 Intracranial aneurysm; LIHC trans rs1814175 0.645 rs1721995 chr11:49915488 A/G cg18944383 chr4:111397179 ENPEP 0.27 6.82 0.35 4.17e-11 Height; LIHC cis rs35110281 0.782 rs9981790 chr21:45045052 G/C cg01579765 chr21:45077557 HSF2BP -0.33 -6.38 -0.33 5.67e-10 Mean corpuscular volume; LIHC cis rs7224737 1.000 rs739637 chr17:40280944 G/C cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg00149659 chr3:10157352 C3orf10 0.65 6.97 0.35 1.63e-11 Alzheimer's disease; LIHC cis rs4853012 0.887 rs6737314 chr2:74339586 A/G cg19729930 chr2:74357872 NA 0.81 16.78 0.67 1.6e-46 Gestational age at birth (maternal effect); LIHC cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.75 0.62 1.8e-38 Prudent dietary pattern; LIHC cis rs60871478 1.000 rs62432899 chr7:826542 G/C cg04727924 chr7:799746 HEATR2 -0.59 -8.06 -0.4 1.3e-14 Cerebrospinal P-tau181p levels; LIHC cis rs7909074 0.766 rs5000415 chr10:45383674 C/T cg05187965 chr10:45406764 TMEM72 -0.27 -6.81 -0.35 4.28e-11 Mean corpuscular volume; LIHC cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg02359409 chr6:42947317 PEX6 -0.47 -6.23 -0.32 1.39e-9 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs1982963 0.950 rs2645750 chr14:52502792 C/A cg10843707 chr14:52510701 NID2 -0.43 -7.18 -0.36 4.27e-12 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs2153535 0.542 rs6912740 chr6:8439959 A/G cg21535247 chr6:8435926 SLC35B3 0.61 7.92 0.39 3.47e-14 Motion sickness; LIHC cis rs694739 0.536 rs11231740 chr11:64046641 C/T cg05555928 chr11:63887634 MACROD1 0.49 8.2 0.41 4.74e-15 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs6061231 0.631 rs927133 chr20:60972109 C/T cg24112000 chr20:60950667 NA -0.61 -9.78 -0.47 4.52e-20 Colorectal cancer; LIHC cis rs8017423 0.935 rs2236403 chr14:90736325 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -14.53 -0.62 1.32e-37 Mortality in heart failure; LIHC cis rs9790314 0.581 rs6806054 chr3:160724978 C/T cg03342759 chr3:160939853 NMD3 -0.57 -7.9 -0.39 3.76e-14 Morning vs. evening chronotype; LIHC cis rs2073300 0.609 rs6137907 chr20:23344511 C/T cg12062639 chr20:23401060 NAPB 1.07 14.34 0.61 7.59e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs3736485 0.934 rs28393906 chr15:51867605 T/A cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1.02e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.44 6.19 0.32 1.75e-9 Schizophrenia; LIHC cis rs7772486 0.754 rs9497419 chr6:146142609 T/C cg23711669 chr6:146136114 FBXO30 0.63 11.35 0.52 1.44e-25 Lobe attachment (rater-scored or self-reported); LIHC cis rs2739330 0.627 rs9608219 chr22:24274119 G/C cg24846343 chr22:24311635 DDTL 0.67 13.0 0.58 1.1e-31 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1113500 0.933 rs1419003 chr1:108616955 A/C cg06207961 chr1:108661230 NA 0.37 7.3 0.37 1.98e-12 Growth-regulated protein alpha levels; LIHC cis rs7395581 0.918 rs1449627 chr11:47290984 T/G cg26139080 chr11:47293733 MADD -0.5 -8.36 -0.41 1.56e-15 HDL cholesterol; LIHC cis rs1506636 1.000 rs689341 chr7:123403974 C/A cg03229431 chr7:123269106 ASB15 0.6 11.92 0.54 1.25e-27 Plateletcrit;Platelet count; LIHC cis rs60871478 1.000 rs7795258 chr7:795227 A/G cg05535760 chr7:792225 HEATR2 0.77 10.98 0.51 3.15e-24 Cerebrospinal P-tau181p levels; LIHC cis rs12220238 1.000 rs10824151 chr10:76092179 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.05 0.31 3.86e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs875971 0.862 rs1981799 chr7:65955559 T/C cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs4919087 0.590 rs1253401 chr10:99050270 G/A cg25902810 chr10:99078978 FRAT1 -0.63 -7.09 -0.36 7.89e-12 Monocyte count; LIHC cis rs7584330 0.554 rs6739456 chr2:238385092 G/C cg08992911 chr2:238395768 MLPH 0.62 6.54 0.33 2.3e-10 Prostate cancer; LIHC cis rs72829446 0.530 rs12325773 chr17:7393871 G/A cg02795151 chr17:7402630 POLR2A 0.53 6.05 0.31 3.87e-9 Androgen levels; LIHC cis rs151997 0.777 rs3846500 chr5:50254488 A/T cg06027927 chr5:50259733 NA -0.57 -8.12 -0.4 8.29e-15 Callous-unemotional behaviour; LIHC cis rs6502050 0.835 rs10163496 chr17:80110867 G/A cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg14393609 chr7:65229607 NA 0.44 6.57 0.33 1.87e-10 Aortic root size; LIHC trans rs7246657 0.943 rs2891699 chr19:37920237 A/G cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs2153535 0.580 rs2327067 chr6:8518482 C/G cg07606381 chr6:8435919 SLC35B3 0.79 11.79 0.54 3.68e-27 Motion sickness; LIHC cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg23758822 chr17:41437982 NA 0.94 17.61 0.69 7.29e-50 Menopause (age at onset); LIHC cis rs35146811 0.961 rs35991721 chr7:99728790 G/T cg03265037 chr7:99691720 MIR25;MCM7;MIR106B;MIR93 0.41 5.83 0.3 1.29e-8 Coronary artery disease; LIHC trans rs7246657 0.943 rs6508711 chr19:37815134 G/T cg10208301 chr11:6592745 DNHD1 0.47 6.75 0.34 6.43e-11 Coronary artery calcification; LIHC cis rs5769765 0.865 rs10854860 chr22:50320029 G/T cg02269571 chr22:50332266 NA -0.66 -9.07 -0.44 9.22e-18 Schizophrenia; LIHC cis rs12477438 0.765 rs6735801 chr2:99657995 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.45 -0.42 8.49e-16 Chronic sinus infection; LIHC cis rs738322 0.553 rs28565947 chr22:38570775 C/G cg25457927 chr22:38595422 NA -0.32 -7.25 -0.36 2.84e-12 Cutaneous nevi; LIHC cis rs600806 0.888 rs4603158 chr1:109879549 C/T cg16275483 chr1:110013120 SYPL2 -0.5 -6.35 -0.32 6.94e-10 Intelligence (multi-trait analysis); LIHC cis rs35110281 0.713 rs1378079 chr21:45011187 A/G cg04455712 chr21:45112962 RRP1B 0.44 7.56 0.38 3.85e-13 Mean corpuscular volume; LIHC cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg25894440 chr7:65020034 NA -0.55 -6.33 -0.32 7.79e-10 Diabetic kidney disease; LIHC cis rs1862618 0.671 rs906631 chr5:56245803 C/G cg12311346 chr5:56204834 C5orf35 0.44 5.99 0.31 5.44e-9 Initial pursuit acceleration; LIHC cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.41 8.77 0.43 8.5e-17 Calcium levels; LIHC cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC trans rs11098499 0.754 rs7672778 chr4:120248585 A/G cg25214090 chr10:38739885 LOC399744 0.51 8.31 0.41 2.32e-15 Corneal astigmatism; LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg21448741 chr8:58168803 NA 0.36 6.7 0.34 8.77e-11 Developmental language disorder (linguistic errors); LIHC cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg24675658 chr1:53192096 ZYG11B 0.57 8.95 0.44 2.24e-17 Monocyte count; LIHC cis rs3857067 0.806 rs72665608 chr4:95093501 T/C cg11021082 chr4:95130006 SMARCAD1 -0.43 -7.54 -0.38 4.21e-13 QT interval; LIHC cis rs10791097 0.739 rs735094 chr11:130725109 G/C cg12179176 chr11:130786555 SNX19 0.73 11.22 0.52 4.4e-25 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg10802521 chr3:52805072 NEK4 -0.44 -7.27 -0.37 2.53e-12 Bipolar disorder; LIHC cis rs7613875 0.663 rs6762477 chr3:50093209 G/A cg05623727 chr3:50126028 RBM5 -0.34 -5.84 -0.3 1.22e-8 Body mass index; LIHC cis rs12451471 0.559 rs12452263 chr17:78079310 T/C cg06718696 chr17:78121285 EIF4A3 0.92 10.84 0.51 9.75e-24 Plateletcrit;Mean corpuscular hemoglobin concentration; LIHC cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg24531977 chr5:56204891 C5orf35 -0.68 -9.79 -0.47 4.04e-20 Initial pursuit acceleration; LIHC cis rs6061231 0.761 rs2427312 chr20:60970591 C/T cg24112000 chr20:60950667 NA -0.59 -6.24 -0.32 1.31e-9 Colorectal cancer; LIHC cis rs763121 0.853 rs3788545 chr22:39065172 A/G cg06022373 chr22:39101656 GTPBP1 0.64 11.09 0.51 1.28e-24 Menopause (age at onset); LIHC trans rs6759952 0.649 rs1382435 chr2:218296003 A/G cg14678744 chr13:113987030 GRTP1 0.37 6.28 0.32 1.02e-9 Thyroid cancer; LIHC cis rs748404 0.723 rs560134 chr15:43555699 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.7 0.34 8.43e-11 Lung cancer; LIHC cis rs4474465 0.688 rs10751296 chr11:78277277 C/T cg27205649 chr11:78285834 NARS2 -0.51 -7.77 -0.39 9.54e-14 Alzheimer's disease (survival time); LIHC cis rs4903214 0.895 rs11621800 chr14:74696753 A/G cg11132536 chr14:74711944 VSX2 -0.24 -5.75 -0.3 2.03e-8 Inflammatory bowel disease; LIHC cis rs651907 0.557 rs35850993 chr3:101437433 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.49 -6.93 -0.35 2.14e-11 Colorectal cancer; LIHC cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg19318889 chr4:1322082 MAEA 0.46 6.42 0.33 4.62e-10 Obesity-related traits; LIHC trans rs637571 0.584 rs594689 chr11:65635559 G/A cg17712092 chr4:129076599 LARP1B -0.67 -9.97 -0.47 1.01e-20 Eosinophil percentage of white cells; LIHC cis rs10463316 0.894 rs7723379 chr5:150765025 T/C cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.04e-10 Metabolite levels (Pyroglutamine); LIHC cis rs7116495 0.609 rs674319 chr11:71775391 T/C cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.07e-17 Severe influenza A (H1N1) infection; LIHC trans rs116095464 0.558 rs112343653 chr5:257174 G/A cg00938859 chr5:1591904 SDHAP3 0.58 7.13 0.36 6.14e-12 Breast cancer; LIHC cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg17971929 chr21:40555470 PSMG1 0.49 7.56 0.38 3.71e-13 Cognitive function; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg23569120 chr2:25470883 DNMT3A 0.37 6.04 0.31 4.08e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs3806843 0.676 rs1583005 chr5:140031537 G/A cg16179182 chr5:140090404 VTRNA1-1 0.38 6.21 0.32 1.5e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs12986413 0.619 rs1859954 chr19:2145481 G/T cg09261902 chr19:2140048 AP3D1 -0.36 -6.15 -0.32 2.14e-9 Height; LIHC cis rs10791097 0.547 rs3829271 chr11:130753912 T/A cg12179176 chr11:130786555 SNX19 0.83 13.68 0.59 2.75e-34 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs34172651 0.876 rs964782 chr16:24811740 T/C cg00152838 chr16:24741724 TNRC6A -0.5 -6.66 -0.34 1.06e-10 Intelligence (multi-trait analysis); LIHC cis rs951366 0.789 rs823097 chr1:205681370 G/A cg11965913 chr1:205819406 PM20D1 0.64 9.34 0.45 1.24e-18 Menarche (age at onset); LIHC cis rs713477 0.901 rs1572612 chr14:55909939 C/T cg13175173 chr14:55914753 NA -0.35 -8.12 -0.4 8.32e-15 Pediatric bone mineral content (femoral neck); LIHC cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.56 8.55 0.42 4.12e-16 Schizophrenia; LIHC cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg06634786 chr22:41940651 POLR3H 0.73 7.59 0.38 3.16e-13 Vitiligo; LIHC cis rs2070488 1.000 rs7433707 chr3:38443180 G/C cg24069376 chr3:38537580 EXOG 0.42 7.6 0.38 2.91e-13 Electrocardiographic conduction measures; LIHC cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg06238570 chr21:40685208 BRWD1 -0.53 -8.71 -0.43 1.34e-16 Cognitive function; LIHC cis rs600806 0.745 rs4970763 chr1:110006349 G/A cg10127483 chr1:110009974 SYPL2 0.49 6.02 0.31 4.55e-9 Intelligence (multi-trait analysis); LIHC trans rs2243480 0.901 rs57126451 chr7:65416306 T/C cg10756647 chr7:56101905 PSPH 1.09 13.5 0.59 1.38e-33 Diabetic kidney disease; LIHC cis rs12478296 0.901 rs7423119 chr2:243005488 T/A cg18898632 chr2:242989856 NA -0.46 -6.48 -0.33 3.16e-10 Obesity-related traits; LIHC cis rs2404602 0.716 rs12437627 chr15:76845050 T/C cg23625390 chr15:77176239 SCAPER 0.36 5.96 0.31 6.3e-9 Blood metabolite levels; LIHC cis rs4853012 0.941 rs60291089 chr2:74344890 T/G cg20891558 chr2:74357851 NA 0.82 16.98 0.68 2.5e-47 Gestational age at birth (maternal effect); LIHC cis rs8081395 0.801 rs2777895 chr17:57879610 A/G cg13753209 chr17:57696993 CLTC -0.46 -7.1 -0.36 7.15e-12 White blood cell count; LIHC cis rs2522056 0.932 rs2522064 chr5:131806488 G/A cg24060327 chr5:131705240 SLC22A5 0.55 7.39 0.37 1.16e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs6793245 0.810 rs7429945 chr3:38591689 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.48 -7.07 -0.36 8.98e-12 QT interval; LIHC cis rs17376456 0.542 rs1982439 chr5:93160560 C/G cg25358565 chr5:93447407 FAM172A -0.78 -7.59 -0.38 3.16e-13 Diabetic retinopathy; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg17340655 chr8:38088874 DDHD2 -0.45 -6.08 -0.31 3.24e-9 Systolic blood pressure; LIHC cis rs477895 1.000 rs2276014 chr11:64081445 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 7.07 0.36 8.61e-12 Mean platelet volume; LIHC cis rs2204008 0.546 rs11519978 chr12:37998170 C/T cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs112790992 1 rs112790992 chr14:105758217 A/C cg06808227 chr14:105710500 BRF1 -0.57 -7.92 -0.39 3.28e-14 Platelet count; LIHC cis rs2070488 0.965 rs4679053 chr3:38523495 G/T cg24069376 chr3:38537580 EXOG 0.43 8.0 0.4 1.98e-14 Electrocardiographic conduction measures; LIHC cis rs8077889 0.957 rs17742929 chr17:41891437 C/T cg26893861 chr17:41843967 DUSP3 0.91 10.22 0.48 1.45e-21 Triglycerides; LIHC cis rs2839186 0.967 rs17176131 chr21:47705237 T/C cg12016809 chr21:47604291 C21orf56 0.41 5.95 0.31 6.57e-9 Testicular germ cell tumor; LIHC cis rs2836974 0.565 rs34304022 chr21:40579619 G/A cg17971929 chr21:40555470 PSMG1 0.71 6.15 0.32 2.16e-9 Cognitive function; LIHC cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg17644776 chr2:200775616 C2orf69 0.42 6.04 0.31 3.98e-9 Osteoporosis; LIHC cis rs4689642 0.666 rs4689658 chr4:7228171 A/G cg21353189 chr4:7228343 SORCS2 -0.35 -6.06 -0.31 3.6e-9 Attention function in attention deficit hyperactive disorder; LIHC cis rs7927592 0.913 rs10896346 chr11:68352671 C/T cg16797656 chr11:68205561 LRP5 0.5 7.8 0.39 7.44e-14 Total body bone mineral density; LIHC cis rs7208859 0.623 rs426434 chr17:28925353 C/T cg13385521 chr17:29058706 SUZ12P 0.7 6.72 0.34 7.56e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs875971 0.862 rs778705 chr7:65861115 G/A cg18252515 chr7:66147081 NA -0.46 -6.81 -0.35 4.49e-11 Aortic root size; LIHC cis rs4927850 1.000 rs4927848 chr3:195738406 A/G cg12923728 chr3:195709715 SDHAP1 -0.74 -9.86 -0.47 2.43e-20 Pancreatic cancer; LIHC trans rs4906332 1.000 rs3783400 chr14:103967045 G/A cg17675199 chr6:35436792 RPL10A 0.34 6.5 0.33 2.78e-10 Coronary artery disease; LIHC cis rs5769765 1.000 rs4824112 chr22:50284345 A/G cg26441486 chr22:50317300 CRELD2 0.37 6.03 0.31 4.18e-9 Schizophrenia; LIHC cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg06558623 chr16:89946397 TCF25 -0.84 -13.02 -0.58 9.48e-32 Skin colour saturation; LIHC cis rs644799 1.000 rs500054 chr11:95593806 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.68 9.6 0.46 1.74e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs6545883 0.929 rs9679557 chr2:61709349 C/A cg15711740 chr2:61764176 XPO1 -0.42 -5.85 -0.3 1.17e-8 Tuberculosis; LIHC cis rs727505 0.954 rs66691367 chr7:124654217 G/T cg23710748 chr7:124431027 NA -0.33 -5.83 -0.3 1.3e-8 Lewy body disease; LIHC cis rs9329289 0.603 rs2458698 chr10:2548452 C/T cg15501526 chr10:2543763 NA 0.25 6.12 0.31 2.53e-9 Age-related hearing impairment; LIHC trans rs7395662 0.591 rs10838968 chr11:48595046 A/G cg03929089 chr4:120376271 NA -0.41 -6.1 -0.31 2.91e-9 HDL cholesterol; LIHC cis rs910316 0.934 rs4903278 chr14:75535019 C/A cg11812906 chr14:75593930 NEK9 0.75 14.87 0.63 6.5e-39 Height; LIHC cis rs2153535 0.601 rs9406160 chr6:8464907 A/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg04267008 chr7:1944627 MAD1L1 -0.46 -7.2 -0.36 3.79e-12 Schizophrenia; LIHC cis rs875971 0.767 rs1643394 chr7:65836094 A/G cg11764359 chr7:65958608 NA 0.85 15.23 0.64 2.39e-40 Aortic root size; LIHC cis rs36051895 0.632 rs12115301 chr9:5180548 A/G cg02405213 chr9:5042618 JAK2 0.63 10.97 0.51 3.44e-24 Pediatric autoimmune diseases; LIHC cis rs2658782 0.547 rs3020064 chr11:93060851 A/G cg15737290 chr11:93063684 CCDC67 0.45 5.85 0.3 1.16e-8 Pulmonary function decline; LIHC cis rs17253792 0.822 rs78429067 chr14:56092551 G/A cg01858014 chr14:56050164 KTN1 -0.69 -6.65 -0.34 1.2e-10 Putamen volume; LIHC cis rs8078723 0.668 rs3859191 chr17:38128714 G/A cg17344932 chr17:38183730 MED24;SNORD124 -0.56 -9.22 -0.45 3.17e-18 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs7216064 1.000 rs9912770 chr17:65868233 C/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.72 -0.47 6.92e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs7116495 0.867 rs4378421 chr11:71761996 T/C cg10381502 chr11:71823885 C11orf51 -1.08 -9.2 -0.45 3.57e-18 Severe influenza A (H1N1) infection; LIHC cis rs7618501 0.633 rs35065728 chr3:50009176 T/C cg21467203 chr3:49911342 NA -0.46 -8.32 -0.41 2.17e-15 Intelligence (multi-trait analysis); LIHC trans rs7874142 0.616 rs4072882 chr9:137687038 A/G cg18109838 chr5:88185987 MEF2C -0.35 -7.09 -0.36 7.79e-12 Longevity; LIHC cis rs8044995 0.636 rs12447119 chr16:68297928 G/A cg09835421 chr16:68378352 PRMT7 -0.63 -6.85 -0.35 3.34e-11 Schizophrenia; LIHC cis rs2073300 0.609 rs17757442 chr20:23421101 A/G cg16736954 chr20:23401023 NAPB -0.73 -8.55 -0.42 4.04e-16 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4237845 0.537 rs10877031 chr12:58266695 A/G cg04478727 chr12:58166393 METTL1;FAM119B 0.59 8.15 0.4 7.11e-15 Intelligence (multi-trait analysis); LIHC cis rs9534288 0.671 rs4942465 chr13:46562687 C/T cg15192986 chr13:46630673 CPB2 -0.48 -7.31 -0.37 1.89e-12 Blood protein levels; LIHC cis rs5167 0.506 rs7257916 chr19:45482884 T/C cg09555818 chr19:45449301 APOC2 -0.22 -6.35 -0.32 6.69e-10 Blood protein levels; LIHC cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.89 0.57 2.96e-31 Prudent dietary pattern; LIHC cis rs9868809 0.772 rs2302295 chr3:48690110 T/C cg07636037 chr3:49044803 WDR6 -0.63 -7.12 -0.36 6.23e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs736408 0.812 rs4687654 chr3:52827566 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.4 6.27 0.32 1.08e-9 Bipolar disorder; LIHC cis rs546131 0.963 rs539044 chr11:34841542 G/T cg06937548 chr11:34938143 PDHX;APIP 0.58 7.88 0.39 4.49e-14 Lung disease severity in cystic fibrosis; LIHC cis rs6061231 0.518 rs639836 chr20:60926223 G/A cg24112000 chr20:60950667 NA 0.45 7.26 0.37 2.64e-12 Colorectal cancer; LIHC cis rs7666738 0.822 rs28512427 chr4:98919029 G/A cg05340658 chr4:99064831 C4orf37 0.64 11.74 0.54 5.79e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs972578 1.000 rs738389 chr22:43332516 T/C cg01576275 chr22:43409880 NA -0.34 -6.07 -0.31 3.39e-9 Mean platelet volume; LIHC cis rs3020736 0.500 rs764481 chr22:42518426 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.2 -0.32 1.67e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs8180040 0.676 rs11130114 chr3:47154651 T/G cg27129171 chr3:47204927 SETD2 0.69 12.39 0.56 2.26e-29 Colorectal cancer; LIHC trans rs1814175 0.817 rs11040700 chr11:50023832 C/T cg03929089 chr4:120376271 NA -0.88 -18.23 -0.7 2.42e-52 Height; LIHC cis rs3820068 0.705 rs16851731 chr1:15860240 A/G cg17385448 chr1:15911702 AGMAT 0.38 6.69 0.34 8.88e-11 Systolic blood pressure; LIHC cis rs3762637 1.000 rs55853677 chr3:122140616 G/A cg24169773 chr3:122142474 KPNA1 -0.5 -9.67 -0.46 1e-19 LDL cholesterol levels; LIHC cis rs5769765 0.862 rs9616774 chr22:50290599 G/A cg26441486 chr22:50317300 CRELD2 0.35 6.33 0.32 7.65e-10 Schizophrenia; LIHC cis rs9818758 0.607 rs11552724 chr3:49156473 C/G cg07636037 chr3:49044803 WDR6 -0.81 -8.4 -0.41 1.2e-15 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs62179067 0.708 rs17363057 chr2:179936172 A/C cg20701897 chr2:179586761 TTN 0.53 5.81 0.3 1.45e-8 Late-onset Alzheimer's disease; LIHC cis rs7757419 0.877 rs7755620 chr6:34435189 T/C cg17518776 chr6:34434842 PACSIN1 -0.3 -6.1 -0.31 2.86e-9 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals; LIHC cis rs12586317 0.513 rs17102962 chr14:35478782 A/T cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.03e-32 Psoriasis; LIHC cis rs2834188 1.000 rs2026254 chr21:34688032 C/T cg04842828 chr21:34696676 IFNAR1 0.45 6.13 0.31 2.36e-9 Narcolepsy; LIHC cis rs11053548 0.538 rs11053556 chr12:10176062 C/T cg04314261 chr12:10163030 CLEC12B 0.38 5.86 0.3 1.08e-8 Systolic blood pressure in sickle cell anemia; LIHC cis rs8078723 0.668 rs56030650 chr17:38131187 C/A cg17467752 chr17:38218738 THRA 0.63 11.0 0.51 2.63e-24 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs2012796 0.743 rs8020575 chr14:81859521 G/A cg23690444 chr14:81902736 NA -0.44 -6.29 -0.32 9.92e-10 Night sleep phenotypes; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg12181579 chr12:114312919 RBM19 0.41 6.15 0.32 2.15e-9 Longevity; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg00280220 chr17:61926910 NA 0.42 6.86 0.35 3.17e-11 Prudent dietary pattern; LIHC trans rs783540 0.521 rs1259176 chr15:83270898 G/A cg18393722 chr15:85113863 UBE2QP1 -0.41 -6.35 -0.32 7.01e-10 Schizophrenia; LIHC cis rs801193 0.660 rs2659914 chr7:66156914 C/T cg11764359 chr7:65958608 NA 0.83 14.78 0.62 1.41e-38 Aortic root size; LIHC cis rs4555082 0.874 rs28625632 chr14:105748849 G/T cg13114125 chr14:105738426 BRF1 -0.74 -9.78 -0.47 4.42e-20 Mean platelet volume;Platelet distribution width; LIHC cis rs2180341 1.000 rs6937287 chr6:127645719 T/A cg24812749 chr6:127587940 RNF146 1.07 16.07 0.66 1.07e-43 Breast cancer; LIHC cis rs7959452 0.684 rs11177615 chr12:69754189 G/A cg22834771 chr12:69754056 YEATS4 -0.53 -9.27 -0.45 2.19e-18 Blood protein levels; LIHC cis rs12477438 0.765 rs6754843 chr2:99680485 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -10.63 -0.5 5.45e-23 Chronic sinus infection; LIHC cis rs7224685 0.569 rs7215798 chr17:4007666 C/G cg09597638 chr17:3907349 NA -0.52 -6.71 -0.34 8.16e-11 Type 2 diabetes; LIHC cis rs7551222 0.716 rs6679717 chr1:204560677 A/G cg20240347 chr1:204465584 NA -0.27 -5.8 -0.3 1.51e-8 Schizophrenia; LIHC cis rs875971 0.862 rs6945775 chr7:65968974 G/A cg18252515 chr7:66147081 NA -0.44 -6.3 -0.32 9.28e-10 Aortic root size; LIHC cis rs7520050 0.966 rs12561806 chr1:46396776 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.72 0.3 2.37e-8 Red blood cell count;Reticulocyte count; LIHC cis rs611744 0.625 rs11779824 chr8:109278689 G/A cg21045802 chr8:109455806 TTC35 0.59 10.33 0.49 5.93e-22 Dupuytren's disease; LIHC trans rs7336933 0.866 rs4941411 chr13:42471498 T/C cg13214892 chr20:39766451 PLCG1 -0.72 -6.04 -0.31 4.05e-9 Calcium levels; LIHC cis rs56235845 0.694 rs6860069 chr5:176755841 C/T cg17509989 chr5:176798049 RGS14 0.65 8.36 0.41 1.62e-15 Hemoglobin concentration;Hematocrit; LIHC cis rs4423214 1.000 rs12790558 chr11:71170905 T/C cg05163923 chr11:71159392 DHCR7 0.89 13.62 0.59 4.7e-34 Vitamin D levels; LIHC cis rs477692 0.673 rs7909964 chr10:131338714 T/C cg05714579 chr10:131428358 MGMT 0.39 6.28 0.32 1.05e-9 Response to temozolomide; LIHC cis rs1691799 0.899 rs1168302 chr12:66737518 C/T cg16791601 chr12:66731901 HELB -0.57 -14.08 -0.61 7.68e-36 White blood cell count (basophil); LIHC cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg03264133 chr6:25882463 NA -0.71 -8.81 -0.43 6.51e-17 Intelligence (multi-trait analysis); LIHC cis rs17102423 0.731 rs1957949 chr14:65542607 C/T cg16583315 chr14:65563665 MAX -0.39 -7.94 -0.39 2.93e-14 Obesity-related traits; LIHC cis rs7602441 0.521 rs1434985 chr2:14767916 C/T cg06545361 chr2:14773388 FAM84A 0.52 6.0 0.31 5.14e-9 Visceral adipose tissue adjusted for BMI; LIHC cis rs17095355 1.000 rs12263484 chr10:111697255 A/G cg00817464 chr10:111662876 XPNPEP1 -0.41 -5.98 -0.31 5.76e-9 Biliary atresia; LIHC cis rs8058578 0.943 rs35629860 chr16:30671532 G/A cg02466173 chr16:30829666 NA -0.46 -7.03 -0.36 1.14e-11 Multiple myeloma; LIHC cis rs9807989 0.507 rs6734762 chr2:103062926 C/T cg03938978 chr2:103052716 IL18RAP 0.31 5.98 0.31 5.51e-9 Asthma; LIHC cis rs7937682 0.774 rs59921976 chr11:111473088 G/A cg09085632 chr11:111637200 PPP2R1B -0.92 -11.19 -0.52 5.46e-25 Primary sclerosing cholangitis; LIHC cis rs765787 0.530 rs2554454 chr15:45521536 A/G cg25801113 chr15:45476975 SHF 0.38 6.37 0.33 5.95e-10 Uric acid levels; LIHC cis rs10508774 1.000 rs1984072 chr10:32911013 C/T cg01819863 chr10:32635814 EPC1 0.64 5.95 0.31 6.59e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6582630 0.555 rs10880613 chr12:38509553 C/T cg13010199 chr12:38710504 ALG10B 0.57 6.82 0.35 4.04e-11 Drug-induced liver injury (flucloxacillin); LIHC cis rs8067354 0.872 rs1295925 chr17:57910263 T/C cg02344993 chr17:57696989 CLTC -0.57 -9.26 -0.45 2.38e-18 Hemoglobin concentration; LIHC cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.47 0.46 4.67e-19 Bipolar disorder; LIHC cis rs1018836 0.828 rs9297871 chr8:91572731 G/A cg16814680 chr8:91681699 NA -0.54 -8.46 -0.42 7.9e-16 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg18252515 chr7:66147081 NA -1.24 -16.09 -0.66 9.25e-44 Diabetic kidney disease; LIHC cis rs11626933 1.000 rs4559843 chr14:90747488 T/C cg07150772 chr14:90864620 CALM1 -0.42 -5.87 -0.3 1.03e-8 Gut microbiota (bacterial taxa); LIHC cis rs7845219 0.544 rs7017487 chr8:95922752 A/G cg16049864 chr8:95962084 TP53INP1 0.44 6.63 0.34 1.3100000000000001e-10 Type 2 diabetes; LIHC cis rs72627123 0.867 rs79250763 chr14:74491121 G/C cg11191049 chr14:74485465 ENTPD5;C14orf45 0.65 5.98 0.31 5.57e-9 Morning vs. evening chronotype; LIHC cis rs9486719 1.000 rs1303852 chr6:96864523 C/T cg06623918 chr6:96969491 KIAA0776 0.75 7.26 0.37 2.64e-12 Migraine;Coronary artery disease; LIHC cis rs4319547 0.656 rs10773088 chr12:122828069 A/T cg05707623 chr12:122985044 ZCCHC8 -0.54 -7.04 -0.36 1.06e-11 Body mass index; LIHC cis rs903552 1.000 rs11634912 chr15:102005510 A/G cg19295451 chr15:102010161 PCSK6 -0.46 -6.32 -0.32 8.18e-10 Diabetic kidney disease; LIHC cis rs651907 0.557 rs62284198 chr3:101474699 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.67 10.82 0.51 1.15e-23 Colorectal cancer; LIHC cis rs7208859 0.573 rs11654035 chr17:29136426 T/C cg14067834 chr17:29058358 SUZ12P 0.71 6.98 0.35 1.57e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg02782426 chr3:40428986 ENTPD3 -0.35 -6.46 -0.33 3.52e-10 Renal cell carcinoma; LIHC trans rs1814175 0.817 rs1851860 chr11:49861310 A/C cg18944383 chr4:111397179 ENPEP 0.27 7.05 0.36 9.99e-12 Height; LIHC cis rs734999 0.588 rs78506337 chr1:2537095 G/A cg18854424 chr1:2615690 NA 0.33 7.22 0.36 3.43e-12 Ulcerative colitis; LIHC cis rs62244186 0.659 rs12108134 chr3:44543030 A/G cg25364880 chr3:44379878 C3orf23 -0.58 -8.21 -0.41 4.69e-15 Depressive symptoms; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05617927 chr15:83654886 FAM103A1 0.37 6.22 0.32 1.48e-9 Cognitive function; LIHC cis rs9888615 0.646 rs2296496 chr14:53380371 A/T cg00686598 chr14:53173677 PSMC6 -0.45 -5.83 -0.3 1.3e-8 Systolic blood pressure; LIHC cis rs6502050 0.835 rs35857672 chr17:80078303 G/A cg13198984 chr17:80129470 CCDC57 -0.33 -5.83 -0.3 1.26e-8 Life satisfaction; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg05917732 chr6:152623304 SYNE1 -0.45 -6.36 -0.33 6.31e-10 Pancreatic cancer; LIHC cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs12188164 0.543 rs2434694 chr5:462734 C/T cg00049323 chr5:472564 LOC25845 0.35 5.85 0.3 1.14e-8 Cystic fibrosis severity; LIHC cis rs2033711 0.783 rs8113810 chr19:58932106 A/G cg13877915 chr19:58951672 ZNF132 0.57 8.87 0.43 4.18e-17 Uric acid clearance; LIHC cis rs739401 0.595 rs6578305 chr11:3001120 C/T cg08508325 chr11:3079039 CARS -0.28 -5.89 -0.3 9.08e-9 Longevity; LIHC cis rs12477438 0.765 rs7591992 chr2:99668954 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs7903847 0.656 rs11189208 chr10:99169172 C/G cg08345082 chr10:99160200 RRP12 -0.36 -5.85 -0.3 1.14e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.29e-12 Bipolar disorder; LIHC cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg23262073 chr20:60523788 NA 0.37 7.55 0.38 4.01e-13 Obesity-related traits; LIHC cis rs1448094 0.512 rs7309500 chr12:86249647 C/T cg02569458 chr12:86230093 RASSF9 0.46 6.19 0.32 1.76e-9 Major depressive disorder; LIHC trans rs11098499 0.909 rs10026736 chr4:120384322 G/C cg25214090 chr10:38739885 LOC399744 0.61 9.66 0.46 1.15e-19 Corneal astigmatism; LIHC cis rs1538970 0.810 rs12067642 chr1:45927517 G/T cg24296786 chr1:45957014 TESK2 -0.52 -7.58 -0.38 3.3e-13 Platelet count; LIHC cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg08888203 chr3:10149979 C3orf24 0.63 7.04 0.36 1.03e-11 Alzheimer's disease; LIHC cis rs2832191 0.740 rs2832168 chr21:30463695 G/A cg24692254 chr21:30365293 RNF160 0.87 15.86 0.65 7.31e-43 Dental caries; LIHC cis rs7582180 0.613 rs12988464 chr2:100946285 A/G cg14675211 chr2:100938903 LONRF2 0.55 8.23 0.41 4.03e-15 Intelligence (multi-trait analysis); LIHC cis rs4819052 0.851 rs2838832 chr21:46664904 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.51 -7.16 -0.36 4.84e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs2204008 0.837 rs34381557 chr12:38181983 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg22168489 chr12:122356033 WDR66 -0.42 -6.74 -0.34 6.88e-11 Mean corpuscular volume; LIHC cis rs1046896 1.000 rs1046875 chr17:80685426 A/G cg00809820 chr17:80708513 TBCD;FN3K -0.33 -5.73 -0.3 2.16e-8 Glycated hemoglobin levels; LIHC cis rs1387259 0.929 rs11168460 chr12:48597365 A/G cg21466736 chr12:48725269 NA -0.7 -10.87 -0.51 7.55e-24 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs11229555 0.609 rs11229451 chr11:58201687 T/C cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs4319547 0.656 rs9788145 chr12:122899522 C/T cg23029597 chr12:123009494 RSRC2 -0.51 -7.31 -0.37 1.88e-12 Body mass index; LIHC cis rs757110 0.590 rs7484027 chr11:17368381 T/A cg01251548 chr11:17372745 DKFZp686O24166 0.4 6.83 0.35 3.91e-11 Type 2 diabetes; LIHC cis rs2806561 0.929 rs2746556 chr1:23524541 G/A cg19743168 chr1:23544995 NA 0.44 8.31 0.41 2.23e-15 Height; LIHC cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg06481639 chr22:41940642 POLR3H 0.6 5.73 0.3 2.15e-8 Vitiligo; LIHC cis rs67478160 0.643 rs34813623 chr14:104263294 A/G cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.4 -0.37 1.08e-12 Schizophrenia; LIHC cis rs6952808 0.594 rs3778969 chr7:2139990 A/G cg02951883 chr7:2050386 MAD1L1 0.65 10.47 0.49 2.02e-22 Bipolar disorder and schizophrenia; LIHC cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.45 0.46 5.54e-19 Bipolar disorder; LIHC cis rs1912483 0.505 rs11079772 chr17:45393739 A/C cg08085267 chr17:45401833 C17orf57 0.56 7.88 0.39 4.29e-14 Coronary artery disease; LIHC cis rs6942756 0.774 rs891545 chr7:128866616 A/C cg02491457 chr7:128862824 NA 0.64 10.41 0.49 3.18e-22 White matter hyperintensity burden; LIHC cis rs968567 0.559 rs174544 chr11:61567753 C/A cg27386326 chr11:61587980 NA 0.69 14.43 0.62 3.29e-37 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; LIHC cis rs8067354 0.645 rs9899611 chr17:57832190 A/G cg13753209 chr17:57696993 CLTC 0.73 11.55 0.53 2.83e-26 Hemoglobin concentration; LIHC trans rs3780486 0.834 rs75443249 chr9:33149207 A/G cg20290983 chr6:43655470 MRPS18A 1.06 19.84 0.73 7.97e-59 IgG glycosylation; LIHC cis rs6963495 0.818 rs56177071 chr7:105165648 C/T cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs847649 0.767 rs7796678 chr7:102778447 C/T cg18108683 chr7:102477205 FBXL13 0.41 6.28 0.32 1.02e-9 Morning vs. evening chronotype; LIHC cis rs9517320 0.515 rs1107379 chr13:99198921 C/T cg20487152 chr13:99095054 FARP1 -0.37 -6.17 -0.32 1.89e-9 Longevity; LIHC cis rs295140 0.566 rs295141 chr2:201163556 C/T cg23649088 chr2:200775458 C2orf69 -0.43 -6.0 -0.31 4.97e-9 QT interval; LIHC cis rs7659604 0.539 rs3217773 chr4:122739121 A/G cg19748678 chr4:122722346 EXOSC9 0.66 10.97 0.51 3.37e-24 Type 2 diabetes; LIHC cis rs2075371 1.000 rs7486 chr7:133975183 A/G cg20476274 chr7:133979776 SLC35B4 0.76 13.09 0.58 5.08e-32 Mean platelet volume; LIHC cis rs7654585 0.645 rs1123943 chr4:25924426 A/G cg10409131 chr4:25915609 C4orf52 -0.56 -9.04 -0.44 1.21e-17 Obesity-related traits; LIHC cis rs34172651 0.917 rs2059134 chr16:24816492 C/T cg00339695 chr16:24857497 SLC5A11 -0.49 -7.66 -0.38 1.95e-13 Intelligence (multi-trait analysis); LIHC cis rs4141404 0.851 rs5997893 chr22:31556103 A/G cg07713946 chr22:31675144 LIMK2 -0.29 -6.24 -0.32 1.27e-9 Paclitaxel-induced neuropathy; LIHC cis rs3096299 0.933 rs889576 chr16:89429653 A/G cg02187348 chr16:89574699 SPG7 -0.44 -6.39 -0.33 5.34e-10 Multiple myeloma (IgH translocation); LIHC trans rs2150462 0.508 rs6475737 chr9:23353924 A/G ch.9.1539394R chr9:104170844 ZNF189 -0.42 -6.41 -0.33 4.73e-10 Neuroticism; LIHC cis rs6088580 0.505 rs6142219 chr20:33256345 G/A cg07148914 chr20:33460835 GGT7 -0.51 -7.19 -0.36 4.14e-12 Glomerular filtration rate (creatinine); LIHC trans rs783540 0.967 rs783523 chr15:83283555 A/G cg18393722 chr15:85113863 UBE2QP1 0.38 6.69 0.34 9.22e-11 Schizophrenia; LIHC cis rs2832077 0.527 rs9981922 chr21:30212718 A/G cg24692254 chr21:30365293 RNF160 -0.61 -9.28 -0.45 2.05e-18 Cognitive test performance; LIHC cis rs9486719 0.857 rs6568392 chr6:96861476 G/T cg06623918 chr6:96969491 KIAA0776 0.64 7.4 0.37 1.05e-12 Migraine;Coronary artery disease; LIHC cis rs17818399 1.000 rs62136864 chr2:46829124 G/A cg02822958 chr2:46747628 ATP6V1E2 0.48 7.5 0.38 5.48e-13 Height; LIHC cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg02290350 chr8:58132656 NA 0.41 8.51 0.42 5.58e-16 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6914276 chr6:8450435 A/T cg23788917 chr6:8435910 SLC35B3 -0.62 -8.81 -0.43 6.57e-17 Motion sickness; LIHC cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.52 -7.43 -0.37 8.66e-13 Lymphocyte counts; LIHC cis rs1008375 1.000 rs10009541 chr4:17682218 C/T cg16339924 chr4:17578868 LAP3 -0.49 -6.51 -0.33 2.6e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9916302 0.904 rs7208274 chr17:37513796 C/T cg00129232 chr17:37814104 STARD3 0.38 6.08 0.31 3.27e-9 Glomerular filtration rate (creatinine); LIHC cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg26818010 chr10:134567672 INPP5A -0.76 -9.03 -0.44 1.26e-17 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg23967809 chr8:141647658 NA 0.43 6.94 0.35 1.99e-11 Cognitive function; LIHC cis rs367615 0.704 rs7704824 chr5:108850278 A/G cg17395555 chr5:108820864 NA 0.37 8.11 0.4 9.22e-15 Colorectal cancer (SNP x SNP interaction); LIHC cis rs1005277 0.691 rs2474558 chr10:38486141 A/C cg25427524 chr10:38739819 LOC399744 0.72 13.31 0.58 7.32e-33 Extrinsic epigenetic age acceleration; LIHC cis rs597539 0.652 rs569777 chr11:68706848 G/A cg06028808 chr11:68637592 NA 0.45 5.77 0.3 1.79e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs748404 0.631 rs7163288 chr15:43671355 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.56 10.02 0.48 7.11e-21 Lung cancer; LIHC cis rs6089829 0.926 rs7273917 chr20:61665975 G/A cg08564027 chr20:61660810 NA 0.39 7.48 0.37 6.39e-13 Prostate cancer (SNP x SNP interaction); LIHC cis rs6456156 0.524 rs6934043 chr6:167466449 C/T cg23791538 chr6:167370224 RNASET2 -0.54 -8.68 -0.42 1.69e-16 Primary biliary cholangitis; LIHC cis rs11123170 0.640 rs2863240 chr2:113970116 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.51 -6.51 -0.33 2.73e-10 Renal function-related traits (BUN); LIHC cis rs2204008 0.837 rs8189467 chr12:38241956 T/C cg26384229 chr12:38710491 ALG10B 0.83 10.63 0.5 5.55e-23 Bladder cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06079273 chr8:97247865 UQCRB -0.39 -6.72 -0.34 7.65e-11 Pancreatic cancer; LIHC cis rs1395 0.710 rs1992291 chr2:27504312 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.46 -6.2 -0.32 1.6e-9 Blood metabolite levels; LIHC cis rs17376456 0.877 rs10059630 chr5:93459807 C/A cg25358565 chr5:93447407 FAM172A 1.12 10.35 0.49 5.17e-22 Diabetic retinopathy; LIHC cis rs1198430 1.000 rs946268 chr1:23747766 A/G cg19827787 chr1:23763612 ASAP3 0.34 6.19 0.32 1.71e-9 Total cholesterol levels; LIHC cis rs25645 0.792 rs8077456 chr17:38128765 C/G cg17467752 chr17:38218738 THRA -0.45 -7.5 -0.38 5.5e-13 Myeloid white cell count; LIHC cis rs12440869 0.649 rs4776929 chr15:67707134 G/C cg08154944 chr15:67813145 C15orf61 -0.38 -5.94 -0.31 6.85e-9 Peak velocity of the mitral A-wave; LIHC cis rs1005277 0.579 rs11011461 chr10:38431427 G/A cg25427524 chr10:38739819 LOC399744 -0.65 -12.36 -0.56 2.91e-29 Extrinsic epigenetic age acceleration; LIHC cis rs7953508 0.711 rs3825198 chr12:93977465 T/A cg18151635 chr12:93972918 NA -0.48 -7.63 -0.38 2.37e-13 Pubertal anthropometrics; LIHC cis rs1023500 0.551 rs133355 chr22:42440285 G/A cg15557168 chr22:42548783 NA -0.42 -6.59 -0.34 1.71e-10 Schizophrenia; LIHC cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg10150615 chr22:24372951 LOC391322 -0.54 -7.78 -0.39 8.66e-14 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7258465 0.965 rs1560118 chr19:18570035 G/A cg10790698 chr19:18539756 SSBP4 -0.36 -7.51 -0.38 5.29e-13 Breast cancer; LIHC cis rs7582720 1.000 rs6725887 chr2:203745885 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 -0.76 -6.38 -0.33 5.6e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs6545883 0.929 rs10190332 chr2:61619267 T/G cg15711740 chr2:61764176 XPO1 0.42 5.85 0.3 1.13e-8 Tuberculosis; LIHC cis rs72781680 1.000 rs72781653 chr2:24215633 T/C cg08917208 chr2:24149416 ATAD2B 0.84 7.73 0.39 1.22e-13 Lymphocyte counts; LIHC cis rs7903847 0.642 rs11189175 chr10:99139609 T/C cg08345082 chr10:99160200 RRP12 -0.38 -6.26 -0.32 1.16e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs6088580 0.524 rs6088570 chr20:33268295 T/C cg07148914 chr20:33460835 GGT7 -0.51 -7.21 -0.36 3.64e-12 Glomerular filtration rate (creatinine); LIHC cis rs739401 0.572 rs410820 chr11:3080102 G/A cg25174290 chr11:3078921 CARS 0.68 10.45 0.49 2.24e-22 Longevity; LIHC cis rs2204008 0.905 rs7294297 chr12:38442573 T/C cg26384229 chr12:38710491 ALG10B 0.58 8.25 0.41 3.52e-15 Bladder cancer; LIHC cis rs10744422 0.925 rs3825143 chr12:123352179 C/T cg25930673 chr12:123319894 HIP1R -0.9 -11.71 -0.53 7.61e-27 Schizophrenia; LIHC cis rs15676 0.947 rs6478854 chr9:131588888 G/C cg13708974 chr9:131466143 PKN3 -0.37 -5.78 -0.3 1.71e-8 Blood metabolite levels; LIHC cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg05896524 chr21:47604654 C21orf56 0.52 8.24 0.41 3.64e-15 Testicular germ cell tumor; LIHC cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg17554472 chr22:41940697 POLR3H 0.56 6.01 0.31 4.84e-9 Vitiligo; LIHC cis rs28830936 0.841 rs4923914 chr15:42119603 C/T cg17847044 chr15:42102381 MAPKBP1 -0.3 -5.96 -0.31 6.21e-9 Diastolic blood pressure; LIHC cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg02931644 chr1:25747376 RHCE -0.32 -6.8 -0.35 4.54e-11 Erythrocyte sedimentation rate; LIHC cis rs9534288 0.797 rs9526132 chr13:46609364 A/G cg15192986 chr13:46630673 CPB2 -0.54 -8.38 -0.41 1.44e-15 Blood protein levels; LIHC cis rs12188164 0.543 rs2434694 chr5:462734 C/T cg07599136 chr5:415885 AHRR 0.39 6.75 0.34 6.32e-11 Cystic fibrosis severity; LIHC cis rs8067545 0.641 rs203457 chr17:19818338 A/C cg13482628 chr17:19912719 NA -0.4 -6.55 -0.33 2.17e-10 Schizophrenia; LIHC cis rs6430585 0.583 rs73957037 chr2:136588031 C/A cg07169764 chr2:136633963 MCM6 1.02 15.33 0.64 9.35e-41 Corneal structure; LIHC cis rs4423214 0.879 rs1792282 chr11:71135166 G/A cg05163923 chr11:71159392 DHCR7 -0.66 -9.06 -0.44 9.94e-18 Vitamin D levels; LIHC cis rs9326248 0.798 rs10892079 chr11:117016824 T/G cg15534755 chr11:117069859 TAGLN 0.34 5.77 0.3 1.75e-8 Blood protein levels; LIHC cis rs3617 0.625 rs2240915 chr3:52859526 T/A cg11645453 chr3:52864694 ITIH4 0.22 5.95 0.31 6.58e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; LIHC cis rs6952808 0.543 rs4719436 chr7:2141239 G/A cg20295408 chr7:1910781 MAD1L1 -0.41 -6.1 -0.31 2.92e-9 Bipolar disorder and schizophrenia; LIHC trans rs877282 0.945 rs10904550 chr10:774177 C/T cg22713356 chr15:30763199 NA 1.12 10.23 0.48 1.36e-21 Uric acid levels; LIHC cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg18252515 chr7:66147081 NA -1.24 -15.84 -0.65 8.89e-43 Diabetic kidney disease; LIHC cis rs7666738 0.830 rs17027058 chr4:98864671 G/A cg05340658 chr4:99064831 C4orf37 0.67 12.44 0.56 1.45e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs1664789 0.904 rs1694061 chr5:53278172 C/T ch.5.1024479R chr5:53302184 ARL15 0.54 8.33 0.41 2.01e-15 Waist circumference adjusted for body mass index; LIHC cis rs8078723 0.738 rs8066582 chr17:38146929 A/G cg17344932 chr17:38183730 MED24;SNORD124 0.66 11.56 0.53 2.55e-26 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs1707322 0.928 rs61785614 chr1:46446047 A/G cg06784218 chr1:46089804 CCDC17 0.36 6.56 0.33 1.98e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs12497850 0.931 rs9311432 chr3:48850443 T/A cg07636037 chr3:49044803 WDR6 0.93 16.94 0.68 3.74e-47 Parkinson's disease; LIHC cis rs9322193 0.847 rs4870054 chr6:150169538 C/T cg13206674 chr6:150067644 NUP43 0.31 6.45 0.33 3.81e-10 Lung cancer; LIHC cis rs12711979 0.509 rs10192699 chr2:3824297 A/G cg17052675 chr2:3827356 NA -0.7 -15.47 -0.64 2.8e-41 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs7208859 0.623 rs55811708 chr17:29104731 G/T cg13385521 chr17:29058706 SUZ12P 0.82 8.06 0.4 1.33e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs67311347 0.955 rs9821036 chr3:40379007 A/G cg16822855 chr3:40428330 ENTPD3 0.34 6.14 0.31 2.35e-9 Renal cell carcinoma; LIHC cis rs3096299 0.685 rs4785568 chr16:89553707 A/G cg16743903 chr16:89593216 SPG7 -0.3 -5.79 -0.3 1.63e-8 Multiple myeloma (IgH translocation); LIHC cis rs9948 0.529 rs62156208 chr2:97383686 A/G cg01990225 chr2:97406019 LMAN2L -0.81 -6.31 -0.32 8.67e-10 Erectile dysfunction and prostate cancer treatment; LIHC trans rs1814175 0.529 rs1988417 chr11:49932430 A/G cg03929089 chr4:120376271 NA -0.73 -10.97 -0.51 3.29e-24 Height; LIHC trans rs17685 0.753 rs1637037 chr7:75692927 C/T cg19862616 chr7:65841803 NCRNA00174 0.92 19.18 0.72 3.65e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg13409248 chr3:40428643 ENTPD3 0.47 7.7 0.38 1.52e-13 Renal cell carcinoma; LIHC cis rs2108622 0.727 rs8101038 chr19:15982864 C/T cg13772218 chr19:15982569 NA 0.37 7.75 0.39 1.06e-13 Circulating phylloquinone levels;Vitamin E levels;Acenocoumarol maintenance dosage;Response to Vitamin E supplementation;Metabolite levels;Warfarin maintenance dose; LIHC cis rs6952808 0.595 rs3800916 chr7:2166072 C/T cg21782813 chr7:2030301 MAD1L1 0.37 6.36 0.33 6.46e-10 Bipolar disorder and schizophrenia; LIHC cis rs78456975 0.506 rs10206900 chr2:1552841 T/C cg01028140 chr2:1542097 TPO -0.44 -6.99 -0.35 1.46e-11 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs6733011 0.578 rs1581251 chr2:99500867 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.45 -6.47 -0.33 3.35e-10 Bipolar disorder; LIHC trans rs7937682 0.889 rs2850247 chr11:111637202 C/A cg18187862 chr3:45730750 SACM1L -0.62 -7.34 -0.37 1.55e-12 Primary sclerosing cholangitis; LIHC cis rs2120019 1.000 rs67544533 chr15:75361539 A/G cg11632617 chr15:75315747 PPCDC -0.45 -6.41 -0.33 4.75e-10 Blood trace element (Zn levels); LIHC cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg11764359 chr7:65958608 NA 0.56 5.96 0.31 6.14e-9 Diabetic kidney disease; LIHC trans rs4906332 1.000 rs10459573 chr14:103925457 A/C cg17675199 chr6:35436792 RPL10A 0.34 6.63 0.34 1.32e-10 Coronary artery disease; LIHC cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg13397359 chr6:42928475 GNMT 0.67 9.77 0.47 4.66e-20 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs8017423 0.935 rs3737035 chr14:90745422 T/C cg14092571 chr14:90743983 NA 0.45 7.03 0.36 1.16e-11 Mortality in heart failure; LIHC cis rs6456156 0.586 rs2017338 chr6:167471714 G/A cg12798992 chr6:167411361 FGFR1OP 0.44 6.8 0.34 4.81e-11 Primary biliary cholangitis; LIHC cis rs8180040 1.000 rs553989 chr3:47400328 A/G cg16586182 chr3:47516702 SCAP 0.55 10.3 0.49 7.69e-22 Colorectal cancer; LIHC trans rs11039798 1.000 rs9667626 chr11:48485877 T/C cg15704280 chr7:45808275 SEPT13 0.62 6.5 0.33 2.81e-10 Axial length; LIHC cis rs11893307 0.507 rs1465304 chr2:191585398 A/G cg10560079 chr2:191398806 TMEM194B -0.42 -6.07 -0.31 3.36e-9 Mean platelet volume; LIHC cis rs7818688 0.697 rs61591488 chr8:95984955 C/T cg16049864 chr8:95962084 TP53INP1 0.6 6.51 0.33 2.69e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs8084351 0.577 rs10163983 chr18:50639009 C/G cg24270629 chr18:50823537 DCC 0.43 6.38 0.33 5.78e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs240764 0.782 rs395521 chr6:101054999 C/T cg09795085 chr6:101329169 ASCC3 0.53 7.4 0.37 1.04e-12 Neuroticism; LIHC cis rs9733 0.596 rs6685702 chr1:150656307 A/G cg18016565 chr1:150552671 MCL1 0.58 11.52 0.53 3.59e-26 Tonsillectomy; LIHC cis rs1670533 1.000 rs6850784 chr4:1059809 G/A cg27284194 chr4:1044797 NA 0.59 8.79 0.43 7.18e-17 Recombination rate (females); LIHC cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg20891558 chr2:74357851 NA -0.79 -15.85 -0.65 8.51e-43 Gestational age at birth (maternal effect); LIHC cis rs67460515 0.926 rs13062740 chr3:161024208 G/A cg17135325 chr3:160939158 NMD3 0.54 7.73 0.39 1.19e-13 Parkinson's disease; LIHC cis rs3770081 0.536 rs7562837 chr2:86306251 T/C cg01119172 chr2:86362222 SNORD94;PTCD3 0.5 8.34 0.41 1.88e-15 Facial emotion recognition (sad faces); LIHC cis rs7772486 0.754 rs857881 chr6:145970793 C/A cg23711669 chr6:146136114 FBXO30 -0.72 -13.11 -0.58 4.47e-32 Lobe attachment (rater-scored or self-reported); LIHC cis rs4665809 1.000 rs6546727 chr2:26275282 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.68 -8.46 -0.42 7.79e-16 Gut microbiome composition (summer); LIHC cis rs7412746 0.611 rs7556661 chr1:150892009 C/T cg17724175 chr1:150552817 MCL1 0.43 8.51 0.42 5.7e-16 Melanoma; LIHC cis rs7927592 0.913 rs7106010 chr11:68365212 C/T cg16797656 chr11:68205561 LRP5 0.49 7.67 0.38 1.83e-13 Total body bone mineral density; LIHC cis rs1670533 0.746 rs688008 chr4:1082829 T/C cg27284194 chr4:1044797 NA 0.61 8.98 0.44 1.91e-17 Recombination rate (females); LIHC cis rs10197940 0.662 rs2432945 chr2:152278414 T/C cg06191203 chr2:152266755 RIF1 -0.46 -7.83 -0.39 6.01e-14 Lung cancer; LIHC cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg14393609 chr7:65229607 NA 0.44 6.56 0.33 2.04e-10 Calcium levels; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg12064134 chr16:90016061 DEF8 0.45 6.17 0.32 1.91e-9 Skin colour saturation; LIHC cis rs365132 1.000 rs35977534 chr5:176335231 T/C cg16309518 chr5:176445507 NA -0.58 -11.52 -0.53 3.76e-26 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs7072216 0.763 rs2274244 chr10:100175218 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -6.38 -0.33 5.7e-10 Metabolite levels; LIHC cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg10217327 chr6:118973057 C6orf204 0.63 6.07 0.31 3.46e-9 Diastolic blood pressure; LIHC cis rs7044106 0.791 rs10984998 chr9:123481516 G/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.52 7.9 0.39 3.77e-14 Hip circumference adjusted for BMI; LIHC cis rs2629540 0.847 rs34032724 chr10:126408869 T/G cg08799069 chr10:126477246 METTL10 0.48 7.54 0.38 4.31e-13 Cocaine dependence; LIHC cis rs911119 0.913 rs6048922 chr20:23578116 G/C cg16589663 chr20:23618590 CST3 0.67 6.99 0.35 1.49e-11 Chronic kidney disease; LIHC trans rs916888 0.773 rs199439 chr17:44793503 A/G cg13957321 chr17:43675089 NA 0.5 7.99 0.4 2.13e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg26831259 chr4:1366826 KIAA1530 -0.39 -6.11 -0.31 2.7e-9 Longevity; LIHC cis rs2839186 0.814 rs12482209 chr21:47664275 C/G cg05896524 chr21:47604654 C21orf56 -0.48 -7.42 -0.37 9.14e-13 Testicular germ cell tumor; LIHC cis rs9818758 0.607 rs9855123 chr3:49229457 C/T cg06212747 chr3:49208901 KLHDC8B -0.66 -5.74 -0.3 2.1e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs8084351 0.539 rs7506999 chr18:50576312 T/G cg24270629 chr18:50823537 DCC 0.41 6.34 0.32 7.31e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg24549020 chr5:56110836 MAP3K1 0.52 6.73 0.34 6.97e-11 Initial pursuit acceleration; LIHC cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg25364880 chr3:44379878 C3orf23 0.47 6.68 0.34 9.7e-11 Depressive symptoms; LIHC cis rs35110281 0.782 rs1584917 chr21:45042365 A/G cg01579765 chr21:45077557 HSF2BP -0.33 -6.14 -0.32 2.23e-9 Mean corpuscular volume; LIHC cis rs34779708 0.733 rs4298846 chr10:35547380 A/G cg03585969 chr10:35415529 CREM 0.75 10.95 0.51 4.15e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1775715 0.737 rs2808078 chr10:32172552 C/T cg14930904 chr10:32216787 ARHGAP12 0.35 6.16 0.32 2.02e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg06238570 chr21:40685208 BRWD1 0.47 7.31 0.37 1.87e-12 Cognitive function; LIHC cis rs2599510 0.840 rs466146 chr2:32539236 A/C cg02381751 chr2:32503542 YIPF4 0.52 7.15 0.36 5.36e-12 Interleukin-18 levels; LIHC cis rs2153535 0.505 rs1335629 chr6:8491863 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.52 0.42 5.19e-16 Motion sickness; LIHC cis rs35110281 0.715 rs2838320 chr21:44995037 A/G cg21573476 chr21:45109991 RRP1B -0.61 -11.6 -0.53 1.78e-26 Mean corpuscular volume; LIHC trans rs79976124 0.797 rs74995761 chr6:66640216 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.65 6.85 0.35 3.54e-11 Type 2 diabetes; LIHC cis rs1949733 0.655 rs2631736 chr4:8478421 C/G cg11789530 chr4:8429930 ACOX3 -0.75 -10.82 -0.51 1.16e-23 Response to antineoplastic agents; LIHC cis rs10504229 0.953 rs6985942 chr8:58173412 T/C cg20607798 chr8:58055168 NA 0.46 5.81 0.3 1.44e-8 Developmental language disorder (linguistic errors); LIHC cis rs3862030 0.503 rs10786673 chr10:104280537 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.84 13.0 0.57 1.16e-31 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg19635926 chr16:89946313 TCF25 0.55 7.36 0.37 1.41e-12 Skin colour saturation; LIHC cis rs2274273 0.840 rs66486619 chr14:55869555 T/G cg01864836 chr14:55583639 NA -0.35 -6.47 -0.33 3.3e-10 Protein biomarker; LIHC cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg05590025 chr7:65112418 INTS4L2 0.62 6.79 0.34 4.9e-11 Diabetic kidney disease; LIHC cis rs875971 0.520 rs2420597 chr7:65915986 A/G cg18876405 chr7:65276391 NA 0.37 6.68 0.34 9.57e-11 Aortic root size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17786844 chr1:32404291 PTP4A2 0.53 7.25 0.36 2.76e-12 Lung function (FEV1/FVC); LIHC cis rs911119 0.866 rs6048920 chr20:23576844 A/G cg16589663 chr20:23618590 CST3 0.65 6.74 0.34 6.62e-11 Chronic kidney disease; LIHC cis rs9611519 1.000 rs9611505 chr22:41540279 T/C cg03806693 chr22:41940476 POLR3H -0.7 -7.57 -0.38 3.56e-13 Neuroticism; LIHC cis rs7592578 0.771 rs62181034 chr2:191354963 C/A cg10560079 chr2:191398806 TMEM194B -0.87 -13.01 -0.58 1.04e-31 Diastolic blood pressure; LIHC cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg16405210 chr4:1374714 KIAA1530 -0.93 -16.21 -0.66 3.02e-44 Longevity; LIHC cis rs11628318 0.614 rs62007936 chr14:103198740 G/A cg23461800 chr14:103021989 NA 0.47 6.33 0.32 7.85e-10 Platelet count; LIHC cis rs1292059 1 rs1292059 chr17:57957888 T/A cg02344993 chr17:57696989 CLTC 0.64 10.03 0.48 6.23e-21 Eosinophil percentage of granulocytes; LIHC cis rs3790645 1.000 rs396997 chr1:26893067 T/C cg17456097 chr1:26900765 RPS6KA1 0.4 5.82 0.3 1.33e-8 Glucose homeostasis traits; LIHC cis rs853679 0.517 rs4713143 chr6:28106759 A/C cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg19774624 chr17:42201019 HDAC5 -0.67 -10.36 -0.49 4.77e-22 Total body bone mineral density; LIHC trans rs1005277 0.579 rs1621040 chr10:38497232 T/C cg04469686 chr1:162760199 HSD17B7 -0.39 -6.04 -0.31 4.03e-9 Extrinsic epigenetic age acceleration; LIHC cis rs7772486 0.846 rs2748499 chr6:146315002 T/C cg13319975 chr6:146136371 FBXO30 -0.38 -6.2 -0.32 1.6e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 1.000 rs875971 chr7:65617595 A/G cg11764359 chr7:65958608 NA -0.87 -15.12 -0.63 6.41e-40 Aortic root size; LIHC cis rs1904096 0.506 rs11097408 chr4:95165662 T/C cg11021082 chr4:95130006 SMARCAD1 -0.49 -9.22 -0.45 3.17e-18 Type 2 diabetes; LIHC cis rs7075426 0.905 rs10887612 chr10:88213946 T/C cg07322936 chr10:88137208 NA 0.51 7.3 0.37 2.07e-12 Migraine without aura; LIHC cis rs2637266 1.000 rs2637270 chr10:78336901 C/T cg18941641 chr10:78392320 NA 0.29 6.19 0.32 1.74e-9 Pulmonary function; LIHC cis rs1816752 0.905 rs9511266 chr13:25012504 C/G cg22771759 chr13:24902376 NA 0.33 6.94 0.35 2.03e-11 Obesity-related traits; LIHC cis rs17428076 0.874 rs62182374 chr2:172685682 T/C cg13550731 chr2:172543902 DYNC1I2 0.38 6.14 0.32 2.3e-9 Myopia; LIHC cis rs9902453 0.845 rs3102558 chr17:28023142 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 11.81 0.54 3.07e-27 Coffee consumption (cups per day); LIHC cis rs8081395 0.741 rs180520 chr17:58015149 T/C cg13753209 chr17:57696993 CLTC 0.39 6.09 0.31 3.09e-9 White blood cell count; LIHC cis rs7552404 0.727 rs12093623 chr1:76256232 T/G cg10523679 chr1:76189770 ACADM 0.58 7.32 0.37 1.79e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs722599 0.715 rs11851433 chr14:75339450 C/T cg08847533 chr14:75593920 NEK9 0.49 7.69 0.38 1.61e-13 IgG glycosylation; LIHC cis rs9291683 0.609 rs13141233 chr4:10028729 T/C cg11266682 chr4:10021025 SLC2A9 0.35 7.43 0.37 8.77e-13 Bone mineral density; LIHC trans rs911555 0.692 rs60235428 chr14:103904350 T/C cg17675199 chr6:35436792 RPL10A -0.44 -9.12 -0.44 6.55e-18 Intelligence (multi-trait analysis); LIHC trans rs2739330 0.796 rs5760097 chr22:24247794 G/C cg06437703 chr8:37914619 EIF4EBP1 -0.48 -7.02 -0.35 1.24e-11 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs9354352 0.967 rs9354351 chr6:66696271 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.6 9.66 0.46 1.08e-19 Initial pursuit acceleration in psychotic disorders; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg04318546 chr15:101147087 ASB7 0.38 6.62 0.34 1.42e-10 Cognitive function; LIHC cis rs765787 0.530 rs2433229 chr15:45515235 C/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.51 -0.38 5.06e-13 Uric acid levels; LIHC cis rs1198430 0.714 rs1198437 chr1:23747424 G/C cg19827787 chr1:23763612 ASAP3 0.28 5.98 0.31 5.58e-9 Total cholesterol levels; LIHC cis rs992157 0.710 rs6719789 chr2:219057810 G/T cg20019365 chr2:219134978 PNKD;AAMP -0.76 -12.58 -0.56 4.36e-30 Colorectal cancer; LIHC cis rs17401966 0.624 rs6696978 chr1:10209557 C/T cg15208524 chr1:10270712 KIF1B -0.43 -5.8 -0.3 1.51e-8 Hepatocellular carcinoma; LIHC cis rs8083850 0.748 rs4423490 chr18:50664398 A/G cg24270629 chr18:50823537 DCC -0.44 -6.49 -0.33 3.1e-10 Intelligence (multi-trait analysis); LIHC cis rs250677 0.652 rs250675 chr5:148438565 A/C cg18129178 chr5:148520854 ABLIM3 0.57 7.62 0.38 2.49e-13 Breast cancer; LIHC cis rs644799 0.965 rs11021313 chr11:95506907 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.92 17.38 0.68 6.28e-49 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs9560113 1.000 rs9555805 chr13:112179765 C/T cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC cis rs10744422 0.920 rs3896871 chr12:123333610 G/T cg22842854 chr12:123319900 HIP1R -0.74 -9.76 -0.47 5.03e-20 Schizophrenia; LIHC cis rs3749237 0.929 rs62260715 chr3:49829326 G/A cg03060546 chr3:49711283 APEH 0.4 6.13 0.31 2.46e-9 Resting heart rate; LIHC cis rs763121 0.853 rs3747174 chr22:39069181 T/C cg14440974 chr22:39074834 NA -0.44 -7.18 -0.36 4.45e-12 Menopause (age at onset); LIHC cis rs7937682 0.883 rs512669 chr11:111467893 G/A cg09085632 chr11:111637200 PPP2R1B -0.92 -11.22 -0.52 4.43e-25 Primary sclerosing cholangitis; LIHC cis rs9902453 0.900 rs12451122 chr17:28486376 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.57 8.74 0.43 1.04e-16 Coffee consumption (cups per day); LIHC cis rs12477438 0.798 rs6732579 chr2:99560239 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.04 -14.13 -0.61 5.25e-36 Chronic sinus infection; LIHC cis rs7937890 0.810 rs10734224 chr11:14424124 G/T cg23387056 chr11:14280742 SPON1 -0.43 -5.83 -0.3 1.31e-8 Mitochondrial DNA levels; LIHC cis rs36051895 0.589 rs16922786 chr9:5200714 A/G cg02405213 chr9:5042618 JAK2 -0.64 -10.64 -0.5 4.9e-23 Pediatric autoimmune diseases; LIHC cis rs561341 0.709 rs8068049 chr17:30183857 T/C cg13647721 chr17:30228624 UTP6 -0.77 -6.47 -0.33 3.3e-10 Hip circumference adjusted for BMI; LIHC cis rs10849893 0.557 rs61955091 chr12:121833975 A/G cg01154721 chr12:121881891 KDM2B -0.4 -6.52 -0.33 2.57e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC cis rs6701037 1.000 rs12747817 chr1:175118895 C/T cg17845761 chr1:175162550 KIAA0040 -0.35 -5.85 -0.3 1.12e-8 Alcohol dependence; LIHC cis rs6001982 0.541 rs17002069 chr22:41050986 C/G cg14879645 chr22:41048474 NA 0.4 5.82 0.3 1.34e-8 Breast cancer; LIHC cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.46 7.04 0.36 1.07e-11 Schizophrenia; LIHC cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg17971929 chr21:40555470 PSMG1 0.83 9.95 0.47 1.23e-20 Cognitive function; LIHC trans rs2832191 0.692 rs2776240 chr21:30310639 C/T cg14791747 chr16:20752902 THUMPD1 -0.5 -6.76 -0.34 5.95e-11 Dental caries; LIHC cis rs6920364 1 rs6920364 chr6:167376466 G/C cg07741184 chr6:167504864 NA -0.29 -6.7 -0.34 8.84e-11 Lung cancer; LIHC cis rs1062177 0.950 rs59580263 chr5:151269577 T/A cg00977110 chr5:151150581 G3BP1 0.49 6.18 0.32 1.78e-9 Preschool internalizing problems; LIHC cis rs9303280 0.806 rs11870965 chr17:38030205 T/A cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.74 0.3 2.08e-8 Self-reported allergy; LIHC cis rs7395581 0.918 rs10501321 chr11:47294626 A/G cg26139080 chr11:47293733 MADD -0.48 -8.03 -0.4 1.53e-14 HDL cholesterol; LIHC cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg05590025 chr7:65112418 INTS4L2 -0.58 -6.49 -0.33 2.93e-10 Diabetic kidney disease; LIHC cis rs4555082 1.000 rs7149013 chr14:105759840 T/C cg10792982 chr14:105748885 BRF1 0.44 5.71 0.3 2.45e-8 Mean platelet volume;Platelet distribution width; LIHC cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg10802521 chr3:52805072 NEK4 -0.45 -7.54 -0.38 4.15e-13 Intelligence (multi-trait analysis); LIHC cis rs4727027 0.800 rs10952796 chr7:148813138 G/C cg23583168 chr7:148888333 NA -0.68 -9.58 -0.46 2.05e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs10911232 0.507 rs10797819 chr1:183006911 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.35 0.49 5.01e-22 Hypertriglyceridemia; LIHC cis rs9457247 0.967 rs2015864 chr6:167381476 T/C cg12798992 chr6:167411361 FGFR1OP -0.59 -9.73 -0.47 6.7e-20 Crohn's disease; LIHC cis rs2303759 0.709 rs3760667 chr19:49814832 C/T cg05022225 chr19:49866942 DKKL1;TEAD2 0.53 7.86 0.39 4.89e-14 Multiple sclerosis; LIHC cis rs3008870 0.959 rs2815353 chr1:67483372 A/G cg02640540 chr1:67518911 SLC35D1 0.42 5.82 0.3 1.34e-8 Lymphocyte percentage of white cells; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg25953789 chr2:220366002 GMPPA 0.47 6.13 0.31 2.49e-9 Systolic blood pressure; LIHC cis rs79057730 0.599 rs4720893 chr7:804434 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.88 9.94 0.47 1.25e-20 Initial pursuit acceleration; LIHC cis rs600806 0.888 rs3853500 chr1:109864269 T/C cg08911820 chr1:110026001 ATXN7L2 -0.6 -7.31 -0.37 1.89e-12 Intelligence (multi-trait analysis); LIHC cis rs7072216 0.727 rs7901577 chr10:100164442 A/G cg26618903 chr10:100175079 PYROXD2 -0.39 -6.37 -0.33 5.97e-10 Metabolite levels; LIHC cis rs2075165 0.901 rs7522860 chr1:156275281 C/T cg07234388 chr1:156261841 TMEM79 0.47 9.07 0.44 9.28e-18 Tonsillectomy; LIHC cis rs7617773 0.925 rs7374376 chr3:48172687 T/C cg11946769 chr3:48343235 NME6 -0.53 -7.16 -0.36 5.02e-12 Coronary artery disease; LIHC cis rs7954584 0.520 rs1169096 chr12:122465836 G/C cg22618164 chr12:122356400 WDR66 -0.45 -7.51 -0.38 5.23e-13 Mean corpuscular volume; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg07759052 chr8:28752150 HMBOX1 -0.29 -6.1 -0.31 2.86e-9 Calcium levels; LIHC cis rs738322 0.934 rs133019 chr22:38573035 A/G cg25457927 chr22:38595422 NA -0.29 -7.18 -0.36 4.38e-12 Cutaneous nevi; LIHC cis rs8017423 0.967 rs55962513 chr14:90729460 C/G cg14092571 chr14:90743983 NA -0.41 -6.53 -0.33 2.34e-10 Mortality in heart failure; LIHC cis rs6788895 1.000 rs73008903 chr3:150465053 C/T cg07663535 chr3:150480033 SIAH2 0.56 7.0 0.35 1.37e-11 Breast cancer; LIHC cis rs651907 0.557 rs35117343 chr3:101445126 A/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.45 -0.33 3.81e-10 Colorectal cancer; LIHC cis rs769267 0.965 rs2074296 chr19:19373689 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.63 9.65 0.46 1.17e-19 Tonsillectomy; LIHC cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg20607798 chr8:58055168 NA 0.49 6.12 0.31 2.57e-9 Developmental language disorder (linguistic errors); LIHC cis rs61677309 0.964 rs56292628 chr11:118163872 G/A cg06090739 chr11:118230722 UBE4A 0.35 6.58 0.34 1.82e-10 Lung cancer in ever smokers; LIHC cis rs6430585 0.583 rs79633114 chr2:136586825 C/T cg15123519 chr2:136567270 LCT -0.39 -5.82 -0.3 1.33e-8 Corneal structure; LIHC cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg02951883 chr7:2050386 MAD1L1 -0.66 -10.7 -0.5 3.09e-23 Bipolar disorder and schizophrenia; LIHC cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.76 0.47 5.3e-20 Platelet count; LIHC cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg23758822 chr17:41437982 NA 0.94 17.99 0.7 2.25e-51 Menopause (age at onset); LIHC trans rs877282 1.000 rs12763443 chr10:771941 G/A cg22713356 chr15:30763199 NA 1.41 12.83 0.57 5.16e-31 Uric acid levels; LIHC cis rs8180040 0.934 rs62260710 chr3:47564462 C/G cg27129171 chr3:47204927 SETD2 -0.54 -8.62 -0.42 2.47e-16 Colorectal cancer; LIHC cis rs9921222 0.509 rs3743883 chr16:404750 T/C cg26913058 chr16:419975 MRPL28 -0.5 -7.6 -0.38 2.87e-13 Bone mineral density (spine);Bone mineral density; LIHC cis rs67311347 1.000 rs4973878 chr3:40407565 C/T cg16822855 chr3:40428330 ENTPD3 0.33 6.02 0.31 4.43e-9 Renal cell carcinoma; LIHC trans rs9329221 0.868 rs7831557 chr8:10280228 C/T cg06636001 chr8:8085503 FLJ10661 -0.5 -6.15 -0.32 2.21e-9 Neuroticism; LIHC cis rs4713118 0.826 rs2893929 chr6:27738732 A/T cg20933634 chr6:27740509 NA 0.48 6.26 0.32 1.15e-9 Parkinson's disease; LIHC trans rs875971 1.000 rs937495 chr7:65779798 A/G cg10756647 chr7:56101905 PSPH -0.44 -6.48 -0.33 3.22e-10 Aortic root size; LIHC cis rs1577917 0.545 rs9294338 chr6:86474368 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.33 6.01 0.31 4.72e-9 Response to antipsychotic treatment; LIHC cis rs9457247 0.740 rs10946204 chr6:167451129 T/C cg23791538 chr6:167370224 RNASET2 -0.54 -8.16 -0.4 6.46e-15 Crohn's disease; LIHC trans rs2797160 1.000 rs2211418 chr6:125995503 G/A cg05039488 chr6:79577232 IRAK1BP1 -0.44 -6.53 -0.33 2.42e-10 Endometrial cancer; LIHC trans rs8073060 0.586 rs2428464 chr17:34021994 C/G cg19694781 chr19:47549865 TMEM160 -1.22 -12.41 -0.56 1.94e-29 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs40363 0.729 rs6501176 chr16:3522197 A/G cg22508957 chr16:3507546 NAT15 -0.52 -7.9 -0.39 3.86e-14 Tuberculosis; LIHC cis rs7208859 0.623 rs73269923 chr17:29102571 C/T cg14067834 chr17:29058358 SUZ12P 0.71 6.99 0.35 1.49e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10508774 1.000 rs72782256 chr10:32978551 C/T cg01819863 chr10:32635814 EPC1 0.63 5.88 0.3 9.88e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs4650994 0.935 rs12039531 chr1:178515612 G/A cg05059571 chr16:84539110 KIAA1609 -0.38 -6.35 -0.32 6.9e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs9596863 0.898 rs9316655 chr13:54319640 A/G ch.13.53330881F chr13:54432880 NA 0.5 7.56 0.38 3.81e-13 Epilepsy and lamotrigine-induced maculopapular eruptions; LIHC trans rs3780486 0.757 rs10121987 chr9:33119818 A/G cg04842962 chr6:43655489 MRPS18A 1.07 25.0 0.8 3.62e-79 IgG glycosylation; LIHC cis rs6545883 0.894 rs4672423 chr2:61435275 C/T cg14146966 chr2:61757674 XPO1 -0.42 -6.86 -0.35 3.25e-11 Tuberculosis; LIHC cis rs240764 0.853 rs10457809 chr6:100984400 C/T cg09795085 chr6:101329169 ASCC3 -0.44 -5.9 -0.3 8.77e-9 Neuroticism; LIHC cis rs7903847 0.619 rs76094900 chr10:99158164 G/A cg20016023 chr10:99160130 RRP12 -0.43 -6.58 -0.34 1.77e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10492096 0.947 rs61918022 chr12:6614521 C/T cg13857086 chr12:6580257 VAMP1 0.58 6.18 0.32 1.87e-9 Hip geometry; LIHC cis rs6754311 0.550 rs10173394 chr2:136522675 C/T cg07305463 chr2:136567211 LCT 0.42 7.79 0.39 8.33e-14 Mosquito bite size; LIHC cis rs6430585 0.583 rs3754689 chr2:136590746 C/T cg07169764 chr2:136633963 MCM6 1.03 16.31 0.66 1.21e-44 Corneal structure; LIHC trans rs10506458 0.915 rs1463821 chr12:63402875 C/G cg22491629 chr6:157744540 C6orf35 0.52 9.66 0.46 1.11e-19 Hemostatic factors and hematological phenotypes; LIHC cis rs4699052 0.963 rs6816055 chr4:104143160 T/C cg16532752 chr4:104119610 CENPE -0.42 -6.71 -0.34 8.25e-11 Testicular germ cell tumor; LIHC cis rs651907 0.557 rs1031710 chr3:101463895 C/T cg11279151 chr3:101281821 RG9MTD1 -0.38 -5.74 -0.3 2.04e-8 Colorectal cancer; LIHC cis rs561341 1.000 rs4795668 chr17:30244554 G/A cg13647721 chr17:30228624 UTP6 0.79 7.44 0.37 8.4e-13 Hip circumference adjusted for BMI; LIHC cis rs826838 0.967 rs1719856 chr12:39127201 C/T cg26384229 chr12:38710491 ALG10B -0.61 -8.98 -0.44 1.87e-17 Heart rate; LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg10755058 chr3:40428713 ENTPD3 0.41 6.89 0.35 2.77e-11 Renal cell carcinoma; LIHC trans rs7726839 0.540 rs72705097 chr5:655067 G/A cg25482853 chr8:67687455 SGK3 0.6 6.06 0.31 3.51e-9 Obesity-related traits; LIHC cis rs6840360 0.571 rs4696110 chr4:152671325 G/A cg22705602 chr4:152727874 NA -0.39 -8.21 -0.41 4.62e-15 Intelligence (multi-trait analysis); LIHC cis rs7552404 1.000 rs4949874 chr1:76161889 T/C cg10523679 chr1:76189770 ACADM 0.65 8.9 0.43 3.23e-17 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs743757 1.000 rs2236973 chr3:50474284 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.52 8.25 0.41 3.43e-15 Diastolic blood pressure; LIHC cis rs11148252 0.553 rs9536219 chr13:53227301 C/T cg02158880 chr13:53174818 NA 0.37 5.74 0.3 2.11e-8 Lewy body disease; LIHC cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg19318889 chr4:1322082 MAEA -0.62 -9.96 -0.47 1.13e-20 Obesity-related traits; LIHC trans rs208520 0.690 rs12213928 chr6:66762978 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.81 9.14 0.44 5.59e-18 Exhaled nitric oxide output; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg22027408 chr19:12902453 JUNB -0.44 -6.7 -0.34 8.58e-11 Pancreatic cancer; LIHC cis rs11098499 0.909 rs7659501 chr4:120371552 G/T cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs4243830 0.737 rs56036909 chr1:6608503 C/T cg22792644 chr1:6614718 TAS1R1;NOL9 0.97 11.69 0.53 8.37e-27 Body mass index; LIHC cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Bipolar disorder; LIHC cis rs1997103 1.000 rs6950311 chr7:55400990 G/A cg17469321 chr7:55412551 NA 0.48 7.08 0.36 8.06e-12 QRS interval (sulfonylurea treatment interaction); LIHC cis rs10744422 1.000 rs3817094 chr12:123332032 T/C cg07706471 chr12:123319906 HIP1R -0.62 -8.23 -0.41 4.12e-15 Schizophrenia; LIHC cis rs4820294 1.000 rs62236665 chr22:38059847 C/A cg26138144 chr22:38071188 LGALS1 0.75 14.01 0.6 1.51e-35 Fat distribution (HIV); LIHC cis rs425277 0.585 rs3107157 chr1:2061969 A/G cg04315214 chr1:2043799 PRKCZ 0.42 6.43 0.33 4.29e-10 Height; LIHC cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg00475322 chr7:917719 C7orf20 0.41 7.01 0.35 1.29e-11 Perceived unattractiveness to mosquitoes; LIHC cis rs17376456 0.877 rs10057814 chr5:93399092 C/G cg25358565 chr5:93447407 FAM172A 1.09 10.33 0.49 5.87e-22 Diabetic retinopathy; LIHC cis rs11792861 0.926 rs58795279 chr9:111851902 A/T cg05043794 chr9:111880884 C9orf5 -0.31 -7.24 -0.36 3.07e-12 Menarche (age at onset); LIHC cis rs7937890 1.000 rs2970334 chr11:14329355 C/T cg02251663 chr11:14281053 SPON1 0.44 6.12 0.31 2.57e-9 Mitochondrial DNA levels; LIHC cis rs919433 0.662 rs2043018 chr2:198236958 G/A cg03934865 chr2:198174659 NA 0.54 8.28 0.41 2.8e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7614311 0.681 rs73117083 chr3:63948455 G/C cg22134162 chr3:63841271 THOC7 -0.55 -6.1 -0.31 2.89e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs17854409 0.803 rs3210314 chr20:61472117 C/A cg05147244 chr20:61493195 TCFL5 1.23 10.89 0.51 6.79e-24 Obesity-related traits; LIHC cis rs2033711 0.870 rs7409473 chr19:58939165 A/G cg13877915 chr19:58951672 ZNF132 0.59 9.35 0.45 1.15e-18 Uric acid clearance; LIHC cis rs589448 0.902 rs315134 chr12:69762713 G/A cg19645103 chr12:69753606 YEATS4 -0.39 -5.86 -0.3 1.09e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs7568458 0.660 rs6722691 chr2:85758352 C/T cg02493740 chr2:85810744 VAMP5 -0.44 -7.47 -0.37 6.87e-13 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs597539 0.652 rs488363 chr11:68658298 C/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.76 10.92 0.51 5.04e-24 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.93 -14.26 -0.61 1.62e-36 Alzheimer's disease; LIHC cis rs240764 0.717 rs151640 chr6:101111521 A/C cg09795085 chr6:101329169 ASCC3 0.46 6.74 0.34 6.89e-11 Neuroticism; LIHC cis rs35110281 0.720 rs162372 chr21:44928863 C/T cg01579765 chr21:45077557 HSF2BP 0.34 6.27 0.32 1.08e-9 Mean corpuscular volume; LIHC cis rs4974559 0.501 rs900013 chr4:1240450 G/A cg02980000 chr4:1222292 CTBP1 -0.85 -6.46 -0.33 3.6e-10 Systolic blood pressure; LIHC cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg22633049 chr21:46681294 NA 0.38 6.44 0.33 4.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs8062405 1.000 rs62037367 chr16:28874547 C/G cg07451762 chr16:28383216 NA 0.32 5.97 0.31 5.92e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6424115 0.830 rs2501423 chr1:24199026 A/C cg10978503 chr1:24200527 CNR2 0.34 8.04 0.4 1.48e-14 Immature fraction of reticulocytes; LIHC cis rs992157 0.965 rs13427681 chr2:219167563 G/C cg00012203 chr2:219082015 ARPC2 0.88 14.42 0.61 3.6e-37 Colorectal cancer; LIHC cis rs4423214 0.959 rs11606611 chr11:71164046 C/G cg05163923 chr11:71159392 DHCR7 0.92 14.15 0.61 4.14e-36 Vitamin D levels; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg14257449 chr1:185285846 IVNS1ABP -0.49 -6.06 -0.31 3.6e-9 Systolic blood pressure; LIHC cis rs244293 1.000 rs183618 chr17:53235974 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.47 6.79 0.34 4.84e-11 Menarche (age at onset); LIHC cis rs10078 0.898 rs2241598 chr5:438564 C/T cg24955955 chr5:415729 AHRR -0.42 -7.84 -0.39 5.67e-14 Fat distribution (HIV); LIHC cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.72 11.58 0.53 2.13e-26 Height; LIHC cis rs7131987 0.903 rs7970390 chr12:29398655 A/G cg00204748 chr12:29376779 FAR2 0.45 8.52 0.42 5.07e-16 QT interval; LIHC cis rs2075165 0.935 rs933489 chr1:156235120 T/C cg10096929 chr1:156261403 TMEM79 0.38 6.33 0.32 7.84e-10 Tonsillectomy; LIHC cis rs1552244 0.688 rs113940455 chr3:10014165 A/C cg13047869 chr3:10149882 C3orf24 0.43 5.8 0.3 1.54e-8 Alzheimer's disease; LIHC cis rs6545883 0.929 rs1209434 chr2:61672958 G/A cg14146966 chr2:61757674 XPO1 0.47 8.15 0.4 7.04e-15 Tuberculosis; LIHC cis rs508618 0.666 rs480902 chr1:231531627 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.64 10.27 0.49 9.28e-22 Red blood cell count; LIHC cis rs875971 0.545 rs6950988 chr7:65976415 C/T cg11764359 chr7:65958608 NA 0.61 8.72 0.43 1.26e-16 Aortic root size; LIHC cis rs3796352 0.892 rs58515094 chr3:52995575 C/T cg04865290 chr3:52927548 TMEM110 -0.51 -5.9 -0.3 8.82e-9 Immune reponse to smallpox (secreted IL-2); LIHC cis rs2204008 0.775 rs11182513 chr12:38560252 G/C cg13010199 chr12:38710504 ALG10B 0.58 6.89 0.35 2.62e-11 Bladder cancer; LIHC cis rs739401 0.588 rs10219272 chr11:3020789 G/A cg20651018 chr11:3035856 CARS -0.35 -5.92 -0.3 7.86e-9 Longevity; LIHC cis rs7927771 0.507 rs7111606 chr11:47787538 G/A cg20307385 chr11:47447363 PSMC3 0.74 11.12 0.52 1.01e-24 Subjective well-being; LIHC cis rs651907 0.535 rs35799195 chr3:101521927 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.64 10.18 0.48 1.96e-21 Colorectal cancer; LIHC cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg11494091 chr17:61959527 GH2 -0.45 -7.73 -0.39 1.19e-13 Height; LIHC cis rs6701037 0.681 rs1057239 chr1:175130204 G/A cg17845761 chr1:175162550 KIAA0040 -0.43 -7.11 -0.36 6.81e-12 Alcohol dependence; LIHC cis rs921968 0.509 rs7571743 chr2:219352572 C/T cg02985541 chr2:219472218 PLCD4 0.43 6.95 0.35 1.84e-11 Mean corpuscular hemoglobin concentration; LIHC trans rs1814175 0.645 rs10444311 chr11:49986906 A/G cg03929089 chr4:120376271 NA -0.84 -15.96 -0.65 3.06e-43 Height; LIHC cis rs9326248 0.954 rs521171 chr11:117064693 C/G cg26566898 chr11:117069891 TAGLN 0.49 7.66 0.38 1.95e-13 Blood protein levels; LIHC cis rs11958404 0.517 rs56344822 chr5:157219957 C/T cg05962755 chr5:157440814 NA 0.67 6.76 0.34 5.96e-11 IgG glycosylation; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg11342453 chr6:26196699 NA 0.52 5.93 0.31 7.33e-9 Gout;Renal underexcretion gout; LIHC cis rs2354432 0.607 rs59689207 chr1:146722484 G/A cg25205988 chr1:146714368 CHD1L -0.91 -10.96 -0.51 3.59e-24 Mitochondrial DNA levels; LIHC cis rs17685 0.712 rs10952842 chr7:75780413 G/A cg16684958 chr7:75615977 POR 0.4 6.57 0.33 1.87e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11112613 0.713 rs10507192 chr12:105948247 A/G cg03607813 chr12:105948248 NA 0.71 15.17 0.63 4.2e-40 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; LIHC cis rs7178375 0.941 rs35497908 chr15:31224071 C/T cg19680485 chr15:31195859 MTMR15 -0.53 -5.85 -0.3 1.15e-8 Hypertriglyceridemia; LIHC cis rs12188164 0.525 rs2561665 chr5:460135 A/G cg00049323 chr5:472564 LOC25845 0.35 5.82 0.3 1.33e-8 Cystic fibrosis severity; LIHC cis rs7539409 0.651 rs910182 chr1:84297117 A/G cg10977910 chr1:84465055 TTLL7 0.71 7.18 0.36 4.38e-12 Alzheimer's disease; LIHC cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg20607798 chr8:58055168 NA 0.59 6.91 0.35 2.36e-11 Developmental language disorder (linguistic errors); LIHC cis rs992157 1.000 rs4674280 chr2:219141458 C/G cg20019365 chr2:219134978 PNKD;AAMP -0.79 -12.66 -0.56 2.18e-30 Colorectal cancer; LIHC cis rs72634258 0.945 rs2294889 chr1:8075934 A/G cg00042356 chr1:8021962 PARK7 0.85 8.33 0.41 1.96e-15 Inflammatory bowel disease; LIHC cis rs11098499 0.913 rs10010696 chr4:120164303 T/C cg09307838 chr4:120376055 NA 0.75 11.08 0.51 1.41e-24 Corneal astigmatism; LIHC cis rs4908768 1.000 rs4908768 chr1:8654764 G/A cg20416874 chr1:8611966 RERE 0.54 7.14 0.36 5.78e-12 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs4243830 0.737 rs11122091 chr1:6609559 C/A cg22792644 chr1:6614718 TAS1R1;NOL9 -0.72 -9.1 -0.44 7.52e-18 Body mass index; LIHC cis rs798554 0.757 rs960273 chr7:2857876 T/C cg19717773 chr7:2847554 GNA12 -0.43 -6.73 -0.34 7.33e-11 Height; LIHC cis rs12477438 0.501 rs2632260 chr2:99771590 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs763121 0.853 rs5757162 chr22:38993370 C/T cg06022373 chr22:39101656 GTPBP1 0.69 11.97 0.54 8.25e-28 Menopause (age at onset); LIHC cis rs8014204 0.935 rs8010840 chr14:75355203 T/C cg08847533 chr14:75593920 NEK9 -0.39 -6.47 -0.33 3.3e-10 Caffeine consumption; LIHC trans rs60843830 1.000 rs62114497 chr2:214837 G/A cg11347411 chr7:150020925 ACTR3C;LRRC61 0.58 7.92 0.39 3.35e-14 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs2072499 0.966 rs2853643 chr1:156184831 G/A cg24450063 chr1:156163899 SLC25A44 1.05 17.09 0.68 8.78e-48 Testicular germ cell tumor; LIHC cis rs1707322 1.000 rs10890380 chr1:46449469 A/G cg03146154 chr1:46216737 IPP 0.48 7.72 0.39 1.33e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11671005 0.735 rs3826682 chr19:58918748 C/T cg25952890 chr19:58913133 NA 0.69 7.4 0.37 1.07e-12 Mean platelet volume; LIHC cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 8.53 0.42 4.82e-16 Platelet count; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg23396286 chr10:99258505 UBTD1;MMS19 0.43 6.42 0.33 4.67e-10 Pancreatic cancer; LIHC cis rs9916302 0.904 rs12452509 chr17:37574722 G/A cg07936489 chr17:37558343 FBXL20 -0.84 -13.48 -0.59 1.65e-33 Glomerular filtration rate (creatinine); LIHC cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.41 6.01 0.31 4.83e-9 Menopause (age at onset); LIHC cis rs2404602 0.692 rs35557205 chr15:77130711 T/G cg23625390 chr15:77176239 SCAPER 0.36 5.85 0.3 1.18e-8 Blood metabolite levels; LIHC cis rs7613875 0.600 rs2624826 chr3:50155468 T/G cg05623727 chr3:50126028 RBM5 -0.35 -6.05 -0.31 3.88e-9 Body mass index; LIHC cis rs6594499 0.872 rs6865932 chr5:110436852 G/C cg04022379 chr5:110408740 TSLP 0.5 8.25 0.41 3.45e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs8017423 0.935 rs11159960 chr14:90740012 C/T cg14092571 chr14:90743983 NA 0.47 7.33 0.37 1.68e-12 Mortality in heart failure; LIHC cis rs11711311 1.000 rs9879760 chr3:113457948 G/A cg15478005 chr3:113465772 ATP6V1A;NAA50 0.48 9.39 0.45 8.39e-19 IgG glycosylation; LIHC cis rs617791 0.669 rs4994056 chr11:65750997 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.55 9.28 0.45 1.98e-18 Breast cancer; LIHC cis rs600806 0.821 rs417270 chr1:109849144 T/C cg08911820 chr1:110026001 ATXN7L2 -0.58 -6.85 -0.35 3.35e-11 Intelligence (multi-trait analysis); LIHC cis rs644799 0.710 rs10765771 chr11:95521044 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.76 13.29 0.58 8.77e-33 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs5769765 1.000 rs5769764 chr22:50270784 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.69 9.04 0.44 1.22e-17 Schizophrenia; LIHC cis rs4803455 0.565 rs2241713 chr19:41869468 C/G cg09537434 chr19:41945824 ATP5SL 0.74 11.53 0.53 3.37e-26 Migraine;Coronary artery disease; LIHC cis rs6545883 0.894 rs6739427 chr2:61452879 T/C cg14146966 chr2:61757674 XPO1 -0.43 -7.14 -0.36 5.61e-12 Tuberculosis; LIHC cis rs9381040 0.610 rs2268195 chr6:41024340 G/A cg25110423 chr6:41068646 NFYA;LOC221442 -0.36 -5.77 -0.3 1.82e-8 Alzheimer's disease (late onset); LIHC cis rs8180040 0.967 rs17411375 chr3:47395135 C/T cg27129171 chr3:47204927 SETD2 -0.65 -11.06 -0.51 1.59e-24 Colorectal cancer; LIHC cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.41 0.53 8.83e-26 Alzheimer's disease; LIHC cis rs1801251 0.896 rs79793315 chr2:233690864 C/T cg25237894 chr2:233734115 C2orf82 -0.56 -10.52 -0.49 1.32e-22 Coronary artery disease; LIHC trans rs1814175 0.904 rs1846289 chr11:49620253 G/A cg15704280 chr7:45808275 SEPT13 -1.0 -21.28 -0.75 1.36e-64 Height; LIHC cis rs6867032 1.000 rs28392808 chr5:2013477 A/G cg26168224 chr5:2018326 NA 0.32 8.18 0.4 5.75e-15 Gut microbiome composition (winter); LIHC cis rs1707322 0.717 rs3014237 chr1:46090252 A/G cg03146154 chr1:46216737 IPP -0.54 -8.84 -0.43 5.1e-17 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11663156 0.920 rs2292043 chr18:51059163 T/C cg24270629 chr18:50823537 DCC -0.47 -6.38 -0.33 5.74e-10 Intelligence (multi-trait analysis); LIHC cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg25897951 chr4:1244024 CTBP1;C4orf42 -0.41 -5.85 -0.3 1.18e-8 Longevity; LIHC cis rs6840360 0.615 rs9996320 chr4:152610587 T/G cg22705602 chr4:152727874 NA -0.36 -7.64 -0.38 2.14e-13 Intelligence (multi-trait analysis); LIHC cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg13395646 chr4:1353034 KIAA1530 -0.42 -6.01 -0.31 4.68e-9 Longevity; LIHC cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg05025164 chr4:1340916 KIAA1530 -0.4 -6.02 -0.31 4.56e-9 Obesity-related traits; LIHC cis rs34779708 0.897 rs4934529 chr10:35302376 T/A cg03585969 chr10:35415529 CREM 0.86 13.15 0.58 2.91e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2842992 0.830 rs1535475 chr6:160148935 T/C cg11366901 chr6:160182831 ACAT2 0.96 16.29 0.66 1.39e-44 Age-related macular degeneration (geographic atrophy); LIHC cis rs10463316 0.894 rs7729216 chr5:150762277 A/G cg03212797 chr5:150827313 SLC36A1 -0.43 -6.56 -0.33 2.02e-10 Metabolite levels (Pyroglutamine); LIHC cis rs3768617 0.903 rs10911251 chr1:183081194 A/C ch.1.3577855R chr1:183094577 LAMC1 0.51 8.11 0.4 9.32e-15 Fuchs's corneal dystrophy; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg08872579 chr1:55265830 TTC22 0.42 6.15 0.32 2.14e-9 Hepatitis; LIHC cis rs2066819 1.000 rs79718165 chr12:56644251 C/T cg26734620 chr12:56694298 CS 1.23 10.54 0.5 1.14e-22 Psoriasis vulgaris; LIHC cis rs12711979 0.740 rs6715434 chr2:3820862 T/G cg17052675 chr2:3827356 NA -0.42 -7.19 -0.36 4.16e-12 Itch intensity from mosquito bite adjusted by bite size; LIHC cis rs6942756 1.000 rs68076553 chr7:128959632 A/G cg02491457 chr7:128862824 NA -0.63 -9.1 -0.44 7.75e-18 White matter hyperintensity burden; LIHC cis rs903552 1.000 rs12903048 chr15:102006325 G/T cg00659931 chr15:102010125 PCSK6 -0.45 -6.11 -0.31 2.79e-9 Diabetic kidney disease; LIHC cis rs12368653 0.591 rs1038914 chr12:58011066 G/A cg12615879 chr12:58013172 SLC26A10 -0.32 -6.46 -0.33 3.61e-10 Multiple sclerosis; LIHC cis rs6088590 0.603 rs6579186 chr20:33282198 G/C cg08999081 chr20:33150536 PIGU 0.62 11.44 0.53 6.86e-26 Coronary artery disease; LIHC cis rs2933343 0.729 rs789224 chr3:128598231 A/C cg24203234 chr3:128598194 ACAD9 0.44 6.18 0.32 1.78e-9 IgG glycosylation; LIHC cis rs9359856 0.510 rs4235839 chr6:90472410 A/G cg13799429 chr6:90582589 CASP8AP2 0.78 8.98 0.44 1.89e-17 Bipolar disorder; LIHC cis rs9916302 0.904 rs2061338 chr17:37421767 T/C cg07936489 chr17:37558343 FBXL20 -0.83 -13.49 -0.59 1.55e-33 Glomerular filtration rate (creatinine); LIHC cis rs17376456 0.825 rs13182631 chr5:93115701 A/G cg25358565 chr5:93447407 FAM172A 1.05 9.5 0.46 3.68e-19 Diabetic retinopathy; LIHC trans rs2832191 0.679 rs2705659 chr21:30363908 G/C cg14791747 chr16:20752902 THUMPD1 -0.49 -6.85 -0.35 3.34e-11 Dental caries; LIHC cis rs739401 0.611 rs7394974 chr11:3038868 C/T cg08508325 chr11:3079039 CARS -0.32 -6.88 -0.35 2.86e-11 Longevity; LIHC cis rs908922 0.584 rs10888500 chr1:152532749 G/A cg20991723 chr1:152506922 NA 0.54 8.91 0.43 3.19e-17 Hair morphology; LIHC cis rs9916302 0.904 rs4795356 chr17:37535631 C/T cg00129232 chr17:37814104 STARD3 0.4 6.34 0.32 7.42e-10 Glomerular filtration rate (creatinine); LIHC cis rs9534288 0.763 rs7989605 chr13:46534036 G/A cg15192986 chr13:46630673 CPB2 -0.54 -8.39 -0.41 1.29e-15 Blood protein levels; LIHC cis rs1670533 1.000 rs10902752 chr4:1056199 C/T cg27284194 chr4:1044797 NA 0.6 8.9 0.43 3.36e-17 Recombination rate (females); LIHC cis rs7605378 0.528 rs7592587 chr2:200786516 C/G cg25936922 chr2:200820526 C2orf60;C2orf47 0.51 6.86 0.35 3.18e-11 Osteoporosis; LIHC cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg21610815 chr2:113994035 PAX8;LOC654433;LOC440839 -0.56 -7.93 -0.39 3.21e-14 Lymphocyte counts; LIHC cis rs6831352 0.918 rs2851251 chr4:100044111 A/G cg12011299 chr4:100065546 ADH4 0.62 10.4 0.49 3.54e-22 Alcohol dependence; LIHC cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.5 -8.02 -0.4 1.75e-14 Prudent dietary pattern; LIHC cis rs7927771 0.864 rs2293580 chr11:47440283 T/A cg20307385 chr11:47447363 PSMC3 0.5 6.47 0.33 3.31e-10 Subjective well-being; LIHC cis rs546131 0.642 rs508062 chr11:34843820 C/G cg06937548 chr11:34938143 PDHX;APIP 0.56 7.2 0.36 3.82e-12 Lung disease severity in cystic fibrosis; LIHC cis rs9814567 1.000 rs7426847 chr3:134267519 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs4727027 0.899 rs6464942 chr7:148826368 T/C cg23583168 chr7:148888333 NA -0.73 -9.99 -0.48 8.47e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs58688157 0.883 rs34793529 chr11:575800 T/G cg16486109 chr11:613632 IRF7 0.57 5.79 0.3 1.59e-8 Systemic lupus erythematosus; LIHC cis rs3106136 0.507 rs13134502 chr4:95304507 G/A cg11021082 chr4:95130006 SMARCAD1 0.35 5.94 0.31 7.02e-9 Capecitabine sensitivity; LIHC cis rs4713118 0.868 rs742047 chr6:27739380 A/G cg20933634 chr6:27740509 NA 0.48 6.26 0.32 1.15e-9 Parkinson's disease; LIHC cis rs10744422 0.858 rs12426809 chr12:123327143 C/T cg18912006 chr12:123335444 HIP1R -0.58 -7.11 -0.36 6.8e-12 Schizophrenia; LIHC cis rs11792861 0.926 rs12683988 chr9:111867290 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.62 8.57 0.42 3.64e-16 Menarche (age at onset); LIHC cis rs7095607 0.560 rs2087344 chr10:69922735 A/G cg18986048 chr10:69913749 MYPN -0.48 -7.1 -0.36 7.09e-12 Lung function (FVC); LIHC cis rs11864453 0.713 rs7191127 chr16:72123992 G/T cg01557791 chr16:72042693 DHODH -0.47 -7.62 -0.38 2.58e-13 Fibrinogen levels; LIHC cis rs10242455 0.702 rs73403247 chr7:99088730 G/A cg18809830 chr7:99032528 PTCD1 -0.83 -6.45 -0.33 3.72e-10 Blood metabolite levels; LIHC cis rs919433 0.963 rs12469546 chr2:198178826 T/C cg10820045 chr2:198174542 NA -0.57 -9.69 -0.46 8.95e-20 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs17083533 1.000 rs17083522 chr6:121727758 A/G cg16423337 chr3:52828818 ITIH3 -0.3 -6.3 -0.32 9.03e-10 Heart rate; LIHC cis rs910316 0.737 rs108621 chr14:75480637 T/C cg11812906 chr14:75593930 NEK9 -0.74 -13.76 -0.6 1.31e-34 Height; LIHC cis rs7945705 0.747 rs2653605 chr11:8993309 C/G cg12365402 chr11:9010492 NRIP3 -0.32 -8.19 -0.41 5.08e-15 Hemoglobin concentration; LIHC cis rs17001868 0.568 rs55769635 chr22:40790101 G/A cg07138101 chr22:40742427 ADSL 0.57 6.81 0.35 4.29e-11 Mammographic density (dense area); LIHC cis rs2292096 1.000 rs16847267 chr1:200820897 C/T cg11814564 chr1:200748674 CAMSAP1L1 -0.43 -5.92 -0.31 7.67e-9 Epilepsy; LIHC cis rs9457247 1.000 rs2149085 chr6:167371110 T/C cg12798992 chr6:167411361 FGFR1OP -0.61 -9.81 -0.47 3.56e-20 Crohn's disease; LIHC cis rs589448 0.933 rs523398 chr12:69752775 C/T cg20891283 chr12:69753455 YEATS4 0.96 22.23 0.77 2.2e-68 Cerebrospinal fluid biomarker levels; LIHC cis rs72781680 0.898 rs72796166 chr2:23939311 G/C cg08917208 chr2:24149416 ATAD2B 0.96 8.22 0.41 4.3e-15 Lymphocyte counts; LIHC cis rs151997 0.629 rs27288 chr5:50194920 T/A cg06027927 chr5:50259733 NA 0.44 6.55 0.33 2.12e-10 Callous-unemotional behaviour; LIHC cis rs56235845 0.964 rs11746443 chr5:176798306 G/A cg16006841 chr5:176797999 RGS14 0.81 12.17 0.55 1.53e-28 Hemoglobin concentration;Hematocrit; LIHC cis rs6952808 0.595 rs3778982 chr7:2166233 T/C cg21782813 chr7:2030301 MAD1L1 0.39 6.6 0.34 1.53e-10 Bipolar disorder and schizophrenia; LIHC cis rs6570726 0.967 rs7772286 chr6:145930423 A/T cg23711669 chr6:146136114 FBXO30 -0.55 -9.56 -0.46 2.4e-19 Lobe attachment (rater-scored or self-reported); LIHC cis rs875971 0.862 rs9791713 chr7:66105198 C/A cg18252515 chr7:66147081 NA 0.48 7.0 0.35 1.36e-11 Aortic root size; LIHC cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg22561889 chr6:118971681 C6orf204 0.55 5.94 0.31 7.13e-9 Diastolic blood pressure; LIHC trans rs2243480 0.803 rs36004293 chr7:65416512 T/C cg10756647 chr7:56101905 PSPH 1.09 13.52 0.59 1.17e-33 Diabetic kidney disease; LIHC cis rs12479064 0.724 rs2309618 chr2:99974473 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -7.04 -0.36 1.08e-11 Chronic sinus infection; LIHC cis rs4665809 1.000 rs4665811 chr2:26260017 A/G cg04944784 chr2:26401820 FAM59B -0.71 -8.87 -0.43 4.07e-17 Gut microbiome composition (summer); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg11050527 chr8:54755511 ATP6V1H 0.43 6.91 0.35 2.31e-11 Pancreatic cancer; LIHC cis rs12368653 0.584 rs7295422 chr12:58099736 G/A cg12615879 chr12:58013172 SLC26A10 0.36 7.1 0.36 7.38e-12 Multiple sclerosis; LIHC cis rs12291225 0.679 rs11023172 chr11:14295367 C/G cg19336497 chr11:14380999 RRAS2 -0.65 -12.85 -0.57 4.18e-31 Sense of smell; LIHC cis rs7917772 0.628 rs4604806 chr10:104373904 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.89 0.39 4.03e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs769267 0.930 rs2288852 chr19:19605348 T/C cg03709012 chr19:19516395 GATAD2A 0.99 18.01 0.7 1.76e-51 Tonsillectomy; LIHC cis rs10847980 0.590 rs1979237 chr12:123325895 C/T cg22842854 chr12:123319900 HIP1R 0.92 10.53 0.49 1.17e-22 Adiponectin levels; LIHC cis rs739401 0.572 rs739400 chr11:3016520 G/A cg25174290 chr11:3078921 CARS 0.59 9.17 0.44 4.45e-18 Longevity; LIHC cis rs8141529 0.748 rs5762874 chr22:29269658 C/G cg02153584 chr22:29168773 CCDC117 0.53 8.31 0.41 2.33e-15 Lymphocyte counts; LIHC cis rs2153535 0.601 rs4960414 chr6:8438541 A/G cg07606381 chr6:8435919 SLC35B3 0.79 11.67 0.53 1.03e-26 Motion sickness; LIHC cis rs34779708 0.931 rs11010067 chr10:35295431 C/G cg03585969 chr10:35415529 CREM -0.78 -11.79 -0.54 3.76e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2250402 0.510 rs8031319 chr15:40323692 A/G cg16127683 chr15:40268777 EIF2AK4 -0.51 -5.86 -0.3 1.09e-8 Corneal curvature; LIHC cis rs1005277 0.540 rs2474598 chr10:38430296 C/T cg00409905 chr10:38381863 ZNF37A 0.61 10.68 0.5 3.74e-23 Extrinsic epigenetic age acceleration; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg21176993 chr11:131374259 NTM 0.4 6.8 0.35 4.58e-11 Cognitive function; LIHC cis rs10751667 0.643 rs7395613 chr11:933873 C/T ch.11.42038R chr11:967971 AP2A2 0.53 9.58 0.46 2.01e-19 Alzheimer's disease (late onset); LIHC cis rs9303280 0.651 rs59716545 chr17:38031857 T/G cg17344932 chr17:38183730 MED24;SNORD124 0.37 5.75 0.3 1.96e-8 Self-reported allergy; LIHC cis rs611744 0.967 rs645241 chr8:109190963 C/T cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs523522 0.673 rs643372 chr12:121022640 C/G cg27279351 chr12:120934652 DYNLL1 0.68 12.04 0.55 4.43e-28 High light scatter reticulocyte count; LIHC cis rs36051895 0.587 rs7019418 chr9:5259847 G/C cg02405213 chr9:5042618 JAK2 -0.63 -10.46 -0.49 2.09e-22 Pediatric autoimmune diseases; LIHC cis rs4820294 0.669 rs35662099 chr22:38053909 C/T cg00292662 chr22:38071168 LGALS1 0.39 6.65 0.34 1.16e-10 Fat distribution (HIV); LIHC cis rs6429082 0.818 rs291383 chr1:235643100 G/A cg26050004 chr1:235667680 B3GALNT2 0.51 7.94 0.39 2.95e-14 Adiposity; LIHC cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg05665937 chr4:1216051 CTBP1 0.45 6.05 0.31 3.86e-9 Obesity-related traits; LIHC cis rs9296092 0.538 rs9461881 chr6:33520041 C/T cg13560919 chr6:33536144 NA -0.38 -6.38 -0.33 5.83e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs6500602 0.727 rs55939215 chr16:4541390 C/G cg13763550 chr16:4524223 NMRAL1;HMOX2 0.42 5.73 0.3 2.22e-8 Schizophrenia; LIHC cis rs1949733 0.848 rs2255501 chr4:8475014 G/A cg11789530 chr4:8429930 ACOX3 -0.61 -7.95 -0.4 2.66e-14 Response to antineoplastic agents; LIHC cis rs17854409 0.881 rs68066790 chr20:61487150 T/A cg05147244 chr20:61493195 TCFL5 1.17 10.91 0.51 5.79e-24 Obesity-related traits; LIHC cis rs6570726 0.755 rs2103633 chr6:145894021 C/T cg13319975 chr6:146136371 FBXO30 -0.39 -6.37 -0.33 6.08e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs4845459 0.933 rs6662654 chr1:152593081 G/T cg20634798 chr1:152595351 LCE3A -0.31 -5.93 -0.31 7.34e-9 Psoriasis; LIHC trans rs2727020 0.587 rs1164658 chr11:49298551 C/A cg03929089 chr4:120376271 NA 0.81 14.36 0.61 6.31e-37 Coronary artery disease; LIHC cis rs7027203 0.688 rs4075733 chr9:96624645 C/T cg14396892 chr9:96623032 NA -0.31 -6.0 -0.31 5.09e-9 DNA methylation (variation); LIHC cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg08345575 chr16:4524283 NMRAL1;HMOX2 0.43 5.88 0.3 9.9e-9 Schizophrenia; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg22015966 chr11:47198573 ARFGAP2 -0.44 -6.13 -0.31 2.38e-9 Alopecia areata; LIHC cis rs2839186 0.903 rs61182475 chr21:47707050 T/A cg05896524 chr21:47604654 C21orf56 0.44 6.59 0.34 1.66e-10 Testicular germ cell tumor; LIHC cis rs9399135 0.967 rs4895436 chr6:135295001 G/A cg24558204 chr6:135376177 HBS1L 0.41 6.69 0.34 9.36e-11 Red blood cell count; LIHC cis rs600806 0.888 rs3768497 chr1:109866230 T/C cg08911820 chr1:110026001 ATXN7L2 -0.59 -7.25 -0.36 2.8e-12 Intelligence (multi-trait analysis); LIHC cis rs2073300 0.609 rs2295238 chr20:23387946 C/G cg12062639 chr20:23401060 NAPB 1.04 14.04 0.6 1.11e-35 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs240764 0.697 rs239199 chr6:101134108 C/T cg09795085 chr6:101329169 ASCC3 0.45 6.16 0.32 2.01e-9 Neuroticism; LIHC trans rs7618501 0.669 rs2230590 chr3:49936102 T/C cg21659725 chr3:3221576 CRBN 0.73 11.46 0.53 6.07e-26 Intelligence (multi-trait analysis); LIHC cis rs10463316 0.779 rs1810084 chr5:150777048 A/G cg03212797 chr5:150827313 SLC36A1 -0.41 -6.12 -0.31 2.6e-9 Metabolite levels (Pyroglutamine); LIHC cis rs10791097 0.608 rs12363140 chr11:130744268 A/C cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg07424592 chr7:64974309 NA 0.8 9.43 0.45 6.25e-19 Diabetic kidney disease; LIHC cis rs4908768 0.539 rs4480384 chr1:8659714 A/G cg20416874 chr1:8611966 RERE -0.6 -10.84 -0.51 1.01e-23 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs11676348 0.846 rs13009946 chr2:219007752 A/C cg20019365 chr2:219134978 PNKD;AAMP -0.41 -5.88 -0.3 9.81e-9 Ulcerative colitis; LIHC cis rs13161895 0.646 rs77997852 chr5:179504925 T/C cg02702477 chr5:179499311 RNF130 0.96 11.71 0.53 7.53e-27 LDL cholesterol; LIHC cis rs1005277 0.579 rs2474599 chr10:38438939 A/G cg00409905 chr10:38381863 ZNF37A -0.61 -10.76 -0.5 1.84e-23 Extrinsic epigenetic age acceleration; LIHC cis rs2637266 0.627 rs1992396 chr10:78482228 T/C cg18941641 chr10:78392320 NA 0.28 6.2 0.32 1.61e-9 Pulmonary function; LIHC cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg21171335 chr12:122356390 WDR66 0.55 8.04 0.4 1.49e-14 Mean corpuscular volume; LIHC cis rs9309473 1.000 rs6715819 chr2:73772309 T/G cg20560298 chr2:73613845 ALMS1 -0.55 -6.51 -0.33 2.64e-10 Metabolite levels; LIHC trans rs2727020 0.576 rs1814175 chr11:49559172 T/C cg15704280 chr7:45808275 SEPT13 -0.98 -20.14 -0.74 4.63e-60 Coronary artery disease; LIHC cis rs921968 0.541 rs832798 chr2:219464810 G/A cg02176678 chr2:219576539 TTLL4 0.53 7.37 0.37 1.32e-12 Mean corpuscular hemoglobin concentration; LIHC cis rs12477438 0.798 rs6732579 chr2:99560239 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.74 -10.61 -0.5 6.33e-23 Chronic sinus infection; LIHC cis rs763121 0.853 rs5750677 chr22:39147715 C/T cg06022373 chr22:39101656 GTPBP1 0.68 12.41 0.56 1.87e-29 Menopause (age at onset); LIHC cis rs2637030 0.515 rs439552 chr5:52978517 G/A cg06476337 chr5:52856530 NDUFS4 0.42 6.78 0.34 5.31e-11 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for body mass index; LIHC cis rs6500602 0.702 rs56895104 chr16:4548132 G/A cg13763550 chr16:4524223 NMRAL1;HMOX2 0.41 5.91 0.3 8.38e-9 Schizophrenia; LIHC trans rs7586879 0.593 rs10200566 chr2:25130462 G/T cg18493069 chr6:108582623 SNX3 -0.38 -6.09 -0.31 2.98e-9 Body mass index; LIHC cis rs7945705 0.782 rs2742545 chr11:8884308 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.51 -9.26 -0.45 2.36e-18 Hemoglobin concentration; LIHC cis rs1775715 0.707 rs1541262 chr10:32179771 A/G cg14930904 chr10:32216787 ARHGAP12 0.36 6.29 0.32 9.98e-10 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.69 11.2 0.52 5.17e-25 Prudent dietary pattern; LIHC cis rs8060686 0.516 rs7194894 chr16:68145062 C/T cg09835421 chr16:68378352 PRMT7 -0.49 -5.78 -0.3 1.69e-8 HDL cholesterol;Metabolic syndrome; LIHC cis rs1577917 0.655 rs9342045 chr6:86425148 C/T cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.36 6.51 0.33 2.68e-10 Response to antipsychotic treatment; LIHC cis rs7707921 0.767 rs862241 chr5:81588011 G/A cg15871215 chr5:81402204 ATG10 0.68 8.24 0.41 3.82e-15 Breast cancer; LIHC cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg12463550 chr7:65579703 CRCP 0.71 7.26 0.37 2.63e-12 Diabetic kidney disease; LIHC cis rs4319547 0.737 rs11058226 chr12:122938958 A/G cg05707623 chr12:122985044 ZCCHC8 -0.56 -7.65 -0.38 2.1e-13 Body mass index; LIHC cis rs782590 0.774 rs782632 chr2:55898290 C/G cg18811423 chr2:55921094 PNPT1 0.88 14.05 0.6 1.06e-35 Metabolic syndrome; LIHC cis rs17270561 0.666 rs4712976 chr6:25842203 C/T cg17691542 chr6:26056736 HIST1H1C 0.44 6.18 0.32 1.81e-9 Iron status biomarkers; LIHC cis rs1538970 0.816 rs9727262 chr1:45998579 T/G cg24296786 chr1:45957014 TESK2 -0.47 -6.4 -0.33 5.01e-10 Platelet count; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg11905131 chr22:24372483 LOC391322 -0.71 -10.51 -0.49 1.46e-22 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs11098499 0.955 rs1511015 chr4:120170473 A/C cg25214090 chr10:38739885 LOC399744 0.52 7.93 0.39 3.24e-14 Corneal astigmatism; LIHC cis rs7756236 0.538 rs6936598 chr6:36626096 T/C cg08179530 chr6:36648295 CDKN1A 0.41 6.05 0.31 3.81e-9 QRS duration; LIHC cis rs965469 0.947 rs6051692 chr20:3244098 T/C cg25506879 chr20:3388711 C20orf194 -0.57 -6.62 -0.34 1.37e-10 IFN-related cytopenia; LIHC cis rs2073300 1.000 rs6137977 chr20:23464191 G/T cg12062639 chr20:23401060 NAPB 0.84 10.22 0.48 1.39e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg23782820 chr8:58130467 NA 0.33 5.95 0.31 6.66e-9 Developmental language disorder (linguistic errors); LIHC cis rs933688 1.000 rs6865495 chr5:90746424 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 21.24 0.75 1.95e-64 Smoking behavior; LIHC cis rs7633770 0.805 rs11130098 chr3:46661926 A/G cg11219411 chr3:46661640 NA -0.53 -9.36 -0.45 1.08e-18 Coronary artery disease; LIHC cis rs77637988 0.604 rs17855177 chr2:48602252 C/T cg00032884 chr2:48540671 FOXN2 0.39 5.98 0.31 5.72e-9 Joint mobility (Beighton score); LIHC cis rs4794202 0.534 rs10428 chr17:45915086 G/A cg10638573 chr17:45915098 SCRN2 0.57 6.22 0.32 1.43e-9 Alzheimer's disease (cognitive decline); LIHC cis rs875971 0.545 rs13311962 chr7:66068129 C/T cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.34 -6.73 -0.34 7.16e-11 Aortic root size; LIHC cis rs17685 0.753 rs10264760 chr7:75749694 A/G cg04592579 chr7:75616294 TMEM120A 0.39 6.73 0.34 7.31e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7777484 0.534 rs2533888 chr7:2831083 T/C cg19717773 chr7:2847554 GNA12 -0.45 -8.8 -0.43 6.92e-17 Height; LIHC cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg18306943 chr3:40428807 ENTPD3 -0.42 -7.51 -0.38 5.31e-13 Renal cell carcinoma; LIHC cis rs332507 0.830 rs11718359 chr3:124395987 G/A cg05980111 chr3:124395277 KALRN 0.46 7.07 0.36 8.83e-12 Plateletcrit; LIHC cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC cis rs6723226 0.765 rs12612824 chr2:32579759 C/T cg02381751 chr2:32503542 YIPF4 -0.76 -11.62 -0.53 1.62e-26 Intelligence (multi-trait analysis); LIHC cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.58 -8.11 -0.4 9.07e-15 Lymphocyte counts; LIHC cis rs12497850 0.897 rs9850134 chr3:48957147 A/G cg07636037 chr3:49044803 WDR6 0.93 16.95 0.68 3.21e-47 Parkinson's disease; LIHC cis rs1046896 0.594 rs8070403 chr17:80865404 A/G cg02398342 chr17:80708632 TBCD;FN3K 0.4 5.96 0.31 6.22e-9 Glycated hemoglobin levels; LIHC cis rs853679 0.517 rs4713144 chr6:28106790 C/G cg23485639 chr6:28045615 ZNF165 0.44 5.84 0.3 1.21e-8 Depression; LIHC cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg14709524 chr16:89940631 TCF25 0.51 6.44 0.33 4.1e-10 Skin colour saturation; LIHC cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 9.38 0.45 9.35e-19 Platelet count; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27054084 chr5:122851781 CSNK1G3 -0.3 -7.09 -0.36 7.84e-12 Cognitive function; LIHC cis rs4319547 0.626 rs11057882 chr12:122875046 A/G cg23029597 chr12:123009494 RSRC2 -0.51 -7.28 -0.37 2.3e-12 Body mass index; LIHC cis rs4665809 0.887 rs28699126 chr2:26357294 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.71 -8.9 -0.43 3.25e-17 Gut microbiome composition (summer); LIHC cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg16606324 chr3:10149918 C3orf24 -0.54 -5.96 -0.31 6.3e-9 Alzheimer's disease; LIHC cis rs11711311 1.000 rs1043132 chr3:113528689 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.38 -6.89 -0.35 2.72e-11 IgG glycosylation; LIHC cis rs651907 0.557 rs2318090 chr3:101474933 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.7 11.67 0.53 1.03e-26 Colorectal cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg20337385 chr14:39644624 PNN -0.55 -6.47 -0.33 3.36e-10 Systolic blood pressure; LIHC cis rs2710642 0.564 rs9989741 chr2:62828377 T/A cg17519650 chr2:63277830 OTX1 0.43 6.77 0.34 5.71e-11 LDL cholesterol levels;LDL cholesterol; LIHC cis rs7523273 0.526 rs2724394 chr1:208017072 T/A cg22525895 chr1:207977042 MIR29B2 -0.59 -9.13 -0.44 6.05e-18 Schizophrenia; LIHC cis rs9790314 0.715 rs898681 chr3:160773098 A/G cg03342759 chr3:160939853 NMD3 -0.6 -7.49 -0.38 5.9e-13 Morning vs. evening chronotype; LIHC cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs908922 0.676 rs6687126 chr1:152530894 T/G cg20991723 chr1:152506922 NA 0.54 8.9 0.43 3.39e-17 Hair morphology; LIHC cis rs929354 0.772 rs3802124 chr7:156970609 G/A cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs2067615 0.579 rs10861657 chr12:107131314 A/G cg15890332 chr12:107067104 RFX4 0.26 6.13 0.31 2.37e-9 Heart rate; LIHC cis rs4561483 0.603 rs11639888 chr16:11934623 G/A cg08843971 chr16:11963173 GSPT1 0.36 6.59 0.34 1.66e-10 Testicular germ cell tumor; LIHC cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg13047869 chr3:10149882 C3orf24 0.59 5.86 0.3 1.1e-8 Alzheimer's disease; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg03942271 chr9:94124362 AUH -0.41 -6.12 -0.31 2.54e-9 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs3820068 0.581 rs59684759 chr1:15919893 A/G cg17385448 chr1:15911702 AGMAT 0.36 6.14 0.32 2.24e-9 Systolic blood pressure; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg00166836 chr6:149721425 MAP3K7IP2;SUMO4 0.42 6.38 0.33 5.82e-10 Immature fraction of reticulocytes; LIHC cis rs9733 0.744 rs2039590 chr1:150813315 G/A cg17724175 chr1:150552817 MCL1 -0.36 -7.13 -0.36 5.91e-12 Tonsillectomy; LIHC cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg16822855 chr3:40428330 ENTPD3 -0.33 -6.01 -0.31 4.87e-9 Renal cell carcinoma; LIHC cis rs11264799 0.520 rs2777965 chr1:157550417 A/C cg18268488 chr1:157545234 FCRL4 0.21 5.72 0.3 2.28e-8 IgA nephropathy; LIHC cis rs7258465 1.000 rs4808804 chr19:18585325 A/G cg10790698 chr19:18539756 SSBP4 -0.35 -7.38 -0.37 1.19e-12 Breast cancer; LIHC cis rs2070488 1.000 rs13074160 chr3:38455650 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 15.66 0.65 4.59e-42 Electrocardiographic conduction measures; LIHC cis rs2066819 1.000 rs41423244 chr12:56693520 A/C cg26714650 chr12:56694279 CS 1.4 13.79 0.6 1.03e-34 Psoriasis vulgaris; LIHC cis rs67311347 0.911 rs6776044 chr3:40377503 T/G cg13409248 chr3:40428643 ENTPD3 0.4 6.42 0.33 4.48e-10 Renal cell carcinoma; LIHC cis rs3849570 1.000 rs9818006 chr3:81828230 A/C cg07356753 chr3:81810745 GBE1 -0.59 -8.05 -0.4 1.37e-14 Waist circumference;Body mass index; LIHC cis rs7712401 0.791 rs4835897 chr5:122121504 C/G cg18764291 chr5:122110994 SNX2 0.37 6.36 0.33 6.38e-10 Mean platelet volume; LIHC trans rs7937682 1.000 rs4936661 chr11:111587495 G/A cg18187862 chr3:45730750 SACM1L -0.55 -6.07 -0.31 3.35e-9 Primary sclerosing cholangitis; LIHC cis rs1538970 0.816 rs34673142 chr1:45985561 G/A cg06784218 chr1:46089804 CCDC17 0.35 5.88 0.3 9.88e-9 Platelet count; LIHC cis rs7614311 0.731 rs3774721 chr3:63954649 A/G cg22134162 chr3:63841271 THOC7 -0.54 -6.06 -0.31 3.61e-9 Lung function (FVC);Lung function (FEV1); LIHC cis rs11955398 0.669 rs11952735 chr5:59939146 T/C cg02684056 chr5:59996105 DEPDC1B 0.4 5.91 0.3 8.27e-9 Intelligence (multi-trait analysis); LIHC cis rs67257959 0.708 rs10412843 chr19:17198287 A/G cg16202187 chr19:17186497 HAUS8;MYO9B 0.37 5.87 0.3 1.04e-8 Selective IgA deficiency; LIHC cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg12373951 chr3:133503437 NA 0.49 8.05 0.4 1.42e-14 Iron status biomarkers; LIHC cis rs4332037 0.802 rs12113633 chr7:1932936 G/A cg23422044 chr7:1970798 MAD1L1 -0.66 -7.53 -0.38 4.6e-13 Bipolar disorder; LIHC cis rs422249 0.634 rs174616 chr11:61629122 C/T cg27386326 chr11:61587980 NA 0.33 6.13 0.31 2.42e-9 Trans fatty acid levels; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05421799 chr2:172778343 HAT1 0.38 6.29 0.32 9.66e-10 Hepatitis; LIHC cis rs1400745 0.718 rs1200414 chr14:35330893 G/A cg16230307 chr14:35515116 FAM177A1 0.39 6.24 0.32 1.32e-9 Monocyte count; LIHC cis rs11711311 1.000 rs7645473 chr3:113516187 T/C cg15478005 chr3:113465772 ATP6V1A;NAA50 0.43 8.3 0.41 2.49e-15 IgG glycosylation; LIHC cis rs921968 0.643 rs3932856 chr2:219320207 C/A cg18887096 chr2:219472410 PLCD4 0.39 7.03 0.36 1.14e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs9858542 0.953 rs3811697 chr3:49590770 C/T cg03060546 chr3:49711283 APEH -0.49 -6.62 -0.34 1.37e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs7520050 0.966 rs6669522 chr1:46397941 A/G cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.91e-9 Red blood cell count;Reticulocyte count; LIHC cis rs7027203 1.000 rs7027203 chr9:96562563 A/C cg14598338 chr9:96623480 NA 0.31 6.2 0.32 1.59e-9 DNA methylation (variation); LIHC cis rs13190036 0.901 rs10072499 chr5:176655237 T/G cg06532880 chr5:176731545 PRELID1;RAB24 0.43 5.86 0.3 1.09e-8 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs1003719 0.715 rs6517405 chr21:38560334 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.72 -0.5 2.65e-23 Eye color traits; LIHC cis rs12908161 0.960 rs17599989 chr15:85285536 A/G cg12863693 chr15:85201151 NMB 0.47 6.84 0.35 3.59e-11 Schizophrenia; LIHC cis rs10744422 1.000 rs7294991 chr12:123286780 C/T cg18912006 chr12:123335444 HIP1R -0.6 -6.86 -0.35 3.33e-11 Schizophrenia; LIHC cis rs9549367 0.713 rs4907593 chr13:113830459 C/T cg00898013 chr13:113819073 PROZ 0.36 6.33 0.32 7.72e-10 Platelet distribution width; LIHC cis rs6963495 0.818 rs73192105 chr7:105167945 T/C cg19920283 chr7:105172520 RINT1 0.69 6.48 0.33 3.25e-10 Bipolar disorder (body mass index interaction); LIHC cis rs1008375 1.000 rs2286771 chr4:17643848 G/A cg15017067 chr4:17643749 FAM184B 0.34 5.85 0.3 1.14e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC trans rs7193541 0.684 rs4888265 chr16:74683737 T/C cg23598604 chr1:99732472 LPPR4 -0.3 -6.2 -0.32 1.63e-9 Multiple myeloma; LIHC cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg24531977 chr5:56204891 C5orf35 -0.68 -9.88 -0.47 2e-20 Initial pursuit acceleration; LIHC cis rs10949834 0.529 rs150861 chr7:73524901 T/C cg07137043 chr7:73588983 EIF4H 0.59 7.39 0.37 1.17e-12 Verbal memory performance (residualized delayed recall change); LIHC cis rs2032447 0.507 rs478349 chr6:25894057 T/C cg12310025 chr6:25882481 NA -1.08 -13.85 -0.6 6.17e-35 Intelligence (multi-trait analysis); LIHC cis rs76419734 0.510 rs17036102 chr4:106603098 C/T cg24545054 chr4:106630052 GSTCD;INTS12 -0.78 -9.15 -0.44 5.32e-18 Post bronchodilator FEV1; LIHC cis rs950776 0.518 rs11630349 chr15:78824608 C/T cg22563815 chr15:78856949 CHRNA5 0.36 6.51 0.33 2.71e-10 Sudden cardiac arrest; LIHC cis rs2153535 0.526 rs1796689 chr6:8536433 A/C cg07606381 chr6:8435919 SLC35B3 0.77 10.98 0.51 3.2e-24 Motion sickness; LIHC trans rs1814175 0.765 rs1721990 chr11:49912154 G/C cg15704280 chr7:45808275 SEPT13 -1.01 -22.59 -0.77 8.57e-70 Height; LIHC cis rs8180040 1.000 rs295442 chr3:47335881 A/C cg16586182 chr3:47516702 SCAP -0.55 -10.37 -0.49 4.33e-22 Colorectal cancer; LIHC cis rs11031096 0.655 rs1822288 chr11:4212478 C/T cg18678763 chr11:4115507 RRM1 0.4 5.85 0.3 1.14e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs12042938 0.507 rs1655299 chr1:231732161 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.58 -7.75 -0.39 1.07e-13 Neuranatomic and neurocognitive phenotypes; LIHC cis rs7572733 0.515 rs6724526 chr2:198858401 A/G cg10820045 chr2:198174542 NA 0.46 6.99 0.35 1.42e-11 Dermatomyositis; LIHC cis rs11792861 0.530 rs1772047 chr9:111679012 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.57 -8.32 -0.41 2.05e-15 Menarche (age at onset); LIHC cis rs7264396 0.677 rs6060553 chr20:34267386 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.69 -11.79 -0.54 3.88e-27 Total cholesterol levels; LIHC cis rs7078219 0.505 rs6584282 chr10:101286495 A/G cg06854084 chr10:101292507 NKX2-3 -0.33 -5.98 -0.31 5.56e-9 Dental caries; LIHC cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg12373951 chr3:133503437 NA 0.43 7.09 0.36 7.5e-12 Iron status biomarkers; LIHC cis rs10489202 0.683 rs202260 chr1:167956167 G/T cg24449463 chr1:168025552 DCAF6 -0.62 -9.69 -0.46 8.74e-20 Schizophrenia; LIHC cis rs400736 0.740 rs225096 chr1:8105600 G/C cg25007680 chr1:8021821 PARK7 0.63 9.66 0.46 1.08e-19 Response to antidepressants and depression; LIHC cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg14983838 chr19:29218262 NA 0.48 7.46 0.37 7.16e-13 Methadone dose in opioid dependence; LIHC trans rs7668874 0.779 rs10018157 chr4:116811858 C/T cg08917878 chr5:172668965 NA -0.31 -6.05 -0.31 3.75e-9 Response to platinum-based chemotherapy (carboplatin); LIHC cis rs9948 1.000 rs62152794 chr2:97485110 T/C cg01990225 chr2:97406019 LMAN2L -0.59 -6.11 -0.31 2.64e-9 Erectile dysfunction and prostate cancer treatment; LIHC cis rs4925386 0.802 rs6142735 chr20:60918087 G/C cg06026331 chr20:60912101 LAMA5 0.64 9.44 0.45 6.04e-19 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); LIHC cis rs2991971 1.000 rs667626 chr1:46020551 T/C cg24296786 chr1:45957014 TESK2 0.49 7.09 0.36 7.61e-12 High light scatter reticulocyte count; LIHC cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg07234388 chr1:156261841 TMEM79 0.53 9.48 0.46 4.25e-19 Tonsillectomy; LIHC cis rs11031096 0.536 rs894459 chr11:4213590 A/G cg18678763 chr11:4115507 RRM1 -0.41 -6.04 -0.31 4.12e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs1005277 0.579 rs1780122 chr10:38529509 C/A cg03665457 chr10:38645376 HSD17B7P2 -0.46 -6.6 -0.34 1.54e-10 Extrinsic epigenetic age acceleration; LIHC cis rs11098699 0.821 rs11098703 chr4:124218462 C/G cg09941581 chr4:124220074 SPATA5 0.33 6.59 0.34 1.69e-10 Mosquito bite size; LIHC cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg10295955 chr4:187884368 NA -0.95 -21.01 -0.75 1.61e-63 Lobe attachment (rater-scored or self-reported); LIHC cis rs765787 0.530 rs11854294 chr15:45527996 A/G cg25801113 chr15:45476975 SHF 0.37 6.36 0.33 6.62e-10 Uric acid levels; LIHC cis rs780096 0.546 rs4665976 chr2:27640325 A/G cg21248554 chr2:27665150 KRTCAP3 -0.46 -6.4 -0.33 5e-10 Total body bone mineral density; LIHC cis rs929354 1.000 rs1182410 chr7:157063837 C/T cg17757837 chr7:157058334 UBE3C -0.79 -13.87 -0.6 5.22e-35 Body mass index; LIHC cis rs17213078 0.505 rs2167531 chr2:106738625 A/G cg16099169 chr2:106886729 NA -0.4 -6.28 -0.32 1.05e-9 Facial morphology (factor 23); LIHC cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg24549020 chr5:56110836 MAP3K1 0.49 6.35 0.32 6.73e-10 Initial pursuit acceleration; LIHC cis rs17401966 0.931 rs4240911 chr1:10307453 A/G cg19773385 chr1:10388646 KIF1B -0.38 -6.92 -0.35 2.3e-11 Hepatocellular carcinoma; LIHC cis rs17152411 1.000 rs17152448 chr10:126675645 C/G cg07906193 chr10:126599966 NA 0.51 8.06 0.4 1.25e-14 Height; LIHC cis rs655641 1.000 rs655641 chr11:85731286 C/G cg09030501 chr11:85779252 PICALM -0.51 -6.21 -0.32 1.56e-9 Platelet count; LIHC cis rs10876993 0.890 rs1082502 chr12:58035706 C/T cg04478727 chr12:58166393 METTL1;FAM119B -0.44 -6.27 -0.32 1.07e-9 Celiac disease or Rheumatoid arthritis; LIHC cis rs7000551 0.751 rs2443494 chr8:22372262 C/G cg13512537 chr8:22265999 SLC39A14 -0.33 -5.82 -0.3 1.33e-8 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs3093024 1.000 rs3093023 chr6:167534290 A/G cg07741184 chr6:167504864 NA -0.28 -6.74 -0.34 6.94e-11 Rheumatoid arthritis; LIHC cis rs2439831 0.850 rs8032649 chr15:44134922 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.55 -6.77 -0.34 5.73e-11 Lung cancer in ever smokers; LIHC cis rs1707322 0.721 rs11211149 chr1:46112218 T/C cg06784218 chr1:46089804 CCDC17 0.41 7.49 0.38 5.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs17854409 0.881 rs6011430 chr20:61497014 C/T cg05147244 chr20:61493195 TCFL5 -1.01 -9.66 -0.46 1.15e-19 Obesity-related traits; LIHC cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg05665937 chr4:1216051 CTBP1 0.44 5.8 0.3 1.47e-8 Obesity-related traits; LIHC cis rs870825 0.616 rs28563856 chr4:185635581 G/A cg04058563 chr4:185651563 MLF1IP 0.64 6.67 0.34 1.01e-10 Blood protein levels; LIHC trans rs10506458 1.000 rs1495013 chr12:63428188 C/T cg22491629 chr6:157744540 C6orf35 -0.58 -10.19 -0.48 1.84e-21 Hemostatic factors and hematological phenotypes; LIHC cis rs1801251 0.711 rs778339 chr2:233739678 T/C cg25237894 chr2:233734115 C2orf82 -0.59 -11.84 -0.54 2.39e-27 Coronary artery disease; LIHC cis rs1003719 0.591 rs2835618 chr21:38503126 A/G cg10648535 chr21:38446584 PIGP;TTC3 -0.73 -11.11 -0.52 1.04e-24 Eye color traits; LIHC cis rs1355223 0.583 rs1396880 chr11:34870552 C/T cg24088639 chr11:34937564 PDHX;APIP 0.38 5.76 0.3 1.83e-8 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs12464559 0.649 rs3922997 chr2:152609704 C/T cg01189475 chr2:152685088 ARL5A 0.62 7.25 0.37 2.72e-12 Response to cognitive-behavioural therapy in anxiety disorder; LIHC cis rs7927771 0.864 rs3781626 chr11:47442893 A/T cg18512352 chr11:47633146 NA -0.25 -5.77 -0.3 1.78e-8 Subjective well-being; LIHC cis rs2836950 0.520 rs2836966 chr21:40637521 A/G cg11890956 chr21:40555474 PSMG1 -0.44 -7.14 -0.36 5.68e-12 Menarche (age at onset); LIHC cis rs875971 1.000 rs6460295 chr7:65882728 T/C cg18876405 chr7:65276391 NA 0.37 6.81 0.35 4.52e-11 Aortic root size; LIHC trans rs9929218 1.000 rs9928847 chr16:68797893 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.8 -0.43 6.68e-17 Colorectal cancer; LIHC trans rs1814175 0.817 rs1319547 chr11:49916705 C/T cg03929089 chr4:120376271 NA -0.9 -18.68 -0.71 3.59e-54 Height; LIHC cis rs7208859 0.623 rs73267858 chr17:29059737 A/G cg13385521 chr17:29058706 SUZ12P 0.84 8.37 0.41 1.49e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs6952808 0.601 rs3778978 chr7:2159817 A/G cg04267008 chr7:1944627 MAD1L1 -0.54 -8.45 -0.42 8.23e-16 Bipolar disorder and schizophrenia; LIHC cis rs4819052 0.851 rs35560973 chr21:46662573 T/C cg11663144 chr21:46675770 NA -0.31 -5.86 -0.3 1.07e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg19500098 chr13:21900506 NA 0.4 6.46 0.33 3.6e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7618501 0.521 rs3774759 chr3:49939120 G/T cg21467203 chr3:49911342 NA -0.59 -10.62 -0.5 5.81e-23 Intelligence (multi-trait analysis); LIHC cis rs1552244 0.572 rs3894322 chr3:10168965 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.28 -0.45 1.96e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs8064024 0.508 rs2037912 chr16:4933939 G/C cg08329684 chr16:4932620 PPL -0.43 -7.56 -0.38 3.85e-13 Cancer; LIHC cis rs858239 0.601 rs4140959 chr7:23170776 C/T cg23682824 chr7:23144976 KLHL7 0.42 6.12 0.31 2.5e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg00684032 chr4:1343700 KIAA1530 -0.51 -7.44 -0.37 8.36e-13 Obesity-related traits; LIHC cis rs12364620 1 rs12364620 chr11:68252123 T/G cg20283391 chr11:68216788 NA -0.52 -7.81 -0.39 6.97e-14 Total body bone mineral density (age 0-15); LIHC cis rs13392177 0.647 rs6718220 chr2:219066518 T/C cg00012203 chr2:219082015 ARPC2 -0.75 -11.3 -0.52 2.18e-25 Pyoderma gangrenosum in inflammatory bowel disease; LIHC cis rs6426558 0.537 rs6699828 chr1:227274591 T/C cg10327440 chr1:227177885 CDC42BPA 0.44 6.8 0.35 4.54e-11 Neutrophil percentage of white cells; LIHC cis rs7727544 0.735 rs274568 chr5:131713578 C/T cg24060327 chr5:131705240 SLC22A5 0.59 8.45 0.42 8.48e-16 Blood metabolite levels; LIHC cis rs1008375 0.800 rs62296338 chr4:17613425 G/T cg16339924 chr4:17578868 LAP3 0.41 5.82 0.3 1.38e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs9733 0.596 rs72700897 chr1:150626038 C/G cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs9790314 0.663 rs10513562 chr3:160743579 G/A cg03342759 chr3:160939853 NMD3 -0.58 -8.0 -0.4 1.94e-14 Morning vs. evening chronotype; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg08708735 chr7:1609515 KIAA1908;PSMG3 -0.43 -6.28 -0.32 1.02e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs922107 0.641 rs10922658 chr1:89981468 G/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.52 -0.38 4.77e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs4332037 0.624 rs58169303 chr7:1883274 T/C cg23422044 chr7:1970798 MAD1L1 -0.54 -6.61 -0.34 1.43e-10 Bipolar disorder; LIHC cis rs9296092 0.517 rs7775914 chr6:33518110 T/C cg13560919 chr6:33536144 NA -0.38 -6.37 -0.33 6.07e-10 Age at smoking initiation in chronic obstructive pulmonary disease; LIHC cis rs7523273 0.586 rs2724359 chr1:207935706 A/G cg22525895 chr1:207977042 MIR29B2 0.64 10.31 0.49 7.14e-22 Schizophrenia; LIHC cis rs965469 1.000 rs2281503 chr20:3263636 G/A cg25506879 chr20:3388711 C20orf194 -0.57 -6.88 -0.35 2.95e-11 IFN-related cytopenia; LIHC cis rs6748734 0.843 rs6749674 chr2:241834501 G/C cg08694578 chr2:241835147 C2orf54 -0.51 -7.12 -0.36 6.38e-12 Urinary metabolites; LIHC cis rs4800452 0.956 rs4239437 chr18:20732224 A/G cg26136497 chr18:20735537 CABLES1 -0.43 -5.79 -0.3 1.59e-8 Height;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); LIHC trans rs877282 0.891 rs34652870 chr10:772218 T/C cg22713356 chr15:30763199 NA 1.4 12.55 0.56 5.75e-30 Uric acid levels; LIHC cis rs9768139 0.708 rs11771764 chr7:158119871 A/G cg06219351 chr7:158114137 PTPRN2 -0.21 -5.94 -0.31 7.08e-9 Calcium levels; LIHC cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg08219700 chr8:58056026 NA 0.53 6.22 0.32 1.49e-9 Developmental language disorder (linguistic errors); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg10553894 chr11:68550534 CPT1A 0.41 6.35 0.32 7.03e-10 Pancreatic cancer; LIHC cis rs365132 0.818 rs6879982 chr5:176351330 A/T cg16309518 chr5:176445507 NA -0.51 -9.37 -0.45 9.98e-19 Menarche and menopause (age at onset);Menopause (age at onset); LIHC cis rs1538970 1.000 rs4660853 chr1:45849090 C/T cg05343316 chr1:45956843 TESK2 0.56 8.41 0.41 1.15e-15 Platelet count; LIHC cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg11502198 chr6:26597334 ABT1 0.59 8.99 0.44 1.74e-17 Intelligence (multi-trait analysis); LIHC cis rs6930083 0.510 rs4713994 chr6:36621533 A/G cg08179530 chr6:36648295 CDKN1A -0.66 -10.11 -0.48 3.38e-21 Coronary artery disease; LIHC cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg06466757 chr4:1255808 NA 0.35 5.93 0.31 7.24e-9 Obesity-related traits; LIHC trans rs1814175 0.645 rs6486022 chr11:49776137 A/G cg15704280 chr7:45808275 SEPT13 -0.95 -19.82 -0.73 8.91e-59 Height; LIHC cis rs9911578 0.704 rs72628393 chr17:56585314 A/T cg12560992 chr17:57184187 TRIM37 -0.97 -17.18 -0.68 3.89e-48 Intelligence (multi-trait analysis); LIHC cis rs9911578 1.000 rs2079703 chr17:56603978 G/A cg12560992 chr17:57184187 TRIM37 -0.98 -17.73 -0.69 2.34e-50 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.520 rs6542865 chr2:99764521 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.23 22.37 0.77 6.21e-69 Chronic sinus infection; LIHC cis rs2832191 0.791 rs2832187 chr21:30485543 T/C cg08807101 chr21:30365312 RNF160 -0.63 -10.01 -0.48 7.58e-21 Dental caries; LIHC cis rs7589728 0.563 rs78168096 chr2:88473575 G/A cg07952391 chr2:88470173 THNSL2 0.85 8.13 0.4 8.16e-15 Plasma clusterin levels; LIHC cis rs7647973 1.000 rs7647973 chr3:49510931 G/A cg07636037 chr3:49044803 WDR6 -0.53 -6.46 -0.33 3.52e-10 Menarche (age at onset); LIHC cis rs2439831 1.000 rs2467739 chr15:43740196 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.62 8.73 0.43 1.12e-16 Lung cancer in ever smokers; LIHC cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg24549020 chr5:56110836 MAP3K1 0.5 6.46 0.33 3.69e-10 Initial pursuit acceleration; LIHC cis rs9914988 0.943 rs9303621 chr17:27161138 A/G cg20469991 chr17:27169893 C17orf63 -0.6 -6.95 -0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01152906 chr10:7861152 TAF3 0.45 6.6 0.34 1.6e-10 Pancreatic cancer; LIHC cis rs17253792 0.822 rs75288952 chr14:56034010 C/T cg01858014 chr14:56050164 KTN1 -0.72 -7.0 -0.35 1.36e-11 Putamen volume; LIHC cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg06882758 chr19:58662330 ZNF329 0.92 6.84 0.35 3.68e-11 Cholesterol, total; LIHC cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg17328964 chr8:145687451 CYHR1 0.46 7.53 0.38 4.68e-13 Age at first birth; LIHC cis rs875971 0.638 rs7793569 chr7:66116633 T/G cg18876405 chr7:65276391 NA -0.43 -7.4 -0.37 1.07e-12 Aortic root size; LIHC cis rs7635838 0.751 rs2437681 chr3:11594075 A/G cg00170343 chr3:11313890 ATG7 -0.41 -5.86 -0.3 1.06e-8 HDL cholesterol; LIHC cis rs72781680 1.000 rs963725 chr2:24148231 T/C cg08917208 chr2:24149416 ATAD2B 0.94 8.07 0.4 1.17e-14 Lymphocyte counts; LIHC cis rs12497850 0.931 rs9840050 chr3:49133310 A/G cg07636037 chr3:49044803 WDR6 0.91 16.14 0.66 5.89e-44 Parkinson's disease; LIHC cis rs6466055 0.777 rs917114 chr7:104907507 C/T cg04380332 chr7:105027541 SRPK2 0.36 6.71 0.34 8.15e-11 Schizophrenia; LIHC cis rs1552244 0.744 rs6763366 chr3:10033544 T/C cg13047869 chr3:10149882 C3orf24 0.42 5.88 0.3 9.53e-9 Alzheimer's disease; LIHC cis rs1185460 0.967 rs1786685 chr11:118938957 G/A cg23280166 chr11:118938394 VPS11 0.6 8.28 0.41 2.73e-15 Coronary artery disease; LIHC cis rs8020095 0.571 rs11158653 chr14:67658895 C/T cg03487553 chr14:67822707 ATP6V1D 0.32 5.72 0.3 2.32e-8 Depression (quantitative trait); LIHC cis rs151997 1.000 rs373030 chr5:50215836 G/A cg06027927 chr5:50259733 NA 0.58 7.84 0.39 5.74e-14 Callous-unemotional behaviour; LIHC cis rs3780378 0.870 rs2149556 chr9:5059440 C/T cg02405213 chr9:5042618 JAK2 -0.52 -9.35 -0.45 1.2e-18 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC cis rs9911578 1.000 rs302854 chr17:56683612 G/A cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs3096299 0.967 rs2965827 chr16:89457350 A/C cg02187348 chr16:89574699 SPG7 -0.53 -8.11 -0.4 9.47e-15 Multiple myeloma (IgH translocation); LIHC cis rs4820294 1.000 rs929039 chr22:38071511 T/C cg26138144 chr22:38071188 LGALS1 0.74 13.55 0.59 9.09e-34 Fat distribution (HIV); LIHC cis rs11122272 0.735 rs2739516 chr1:231505527 G/A cg06096015 chr1:231504339 EGLN1 0.51 9.35 0.45 1.14e-18 Hemoglobin concentration; LIHC cis rs9914988 0.887 rs2070265 chr17:27075423 A/G cg20469991 chr17:27169893 C17orf63 0.6 6.95 0.35 1.9e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC trans rs2727020 0.553 rs7479975 chr11:49581964 C/G cg03929089 chr4:120376271 NA -0.88 -16.92 -0.68 4.48e-47 Coronary artery disease; LIHC cis rs9434723 0.841 rs6685399 chr1:9299294 C/T cg04199779 chr1:9294473 H6PD 0.55 5.79 0.3 1.61e-8 Height; LIHC cis rs67478160 0.571 rs1155751 chr14:104286547 C/G cg08213375 chr14:104286397 PPP1R13B 0.64 12.26 0.55 6.75e-29 Schizophrenia; LIHC cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg02290350 chr8:58132656 NA 0.41 8.48 0.42 7.05e-16 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.830 rs587360 chr7:65522698 C/A cg18876405 chr7:65276391 NA 0.41 7.35 0.37 1.49e-12 Aortic root size; LIHC cis rs77106637 0.860 rs11603334 chr11:72432985 G/A cg03713592 chr11:72463424 ARAP1 1.14 10.04 0.48 6e-21 Type 2 diabetes; LIHC cis rs35110281 0.782 rs1454650 chr21:45012353 C/T cg04455712 chr21:45112962 RRP1B 0.47 8.1 0.4 1e-14 Mean corpuscular volume; LIHC cis rs738322 0.532 rs9622746 chr22:38564041 C/G cg25457927 chr22:38595422 NA -0.31 -7.03 -0.36 1.13e-11 Cutaneous nevi; LIHC cis rs1371867 0.817 rs1788208 chr8:101312515 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -8.91 -0.43 3e-17 Atrioventricular conduction; LIHC cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg05590025 chr7:65112418 INTS4L2 -0.63 -6.91 -0.35 2.35e-11 Diabetic kidney disease; LIHC cis rs17001868 0.568 rs760700 chr22:40800071 C/T cg07138101 chr22:40742427 ADSL -0.53 -6.31 -0.32 8.41e-10 Mammographic density (dense area); LIHC trans rs9914544 0.545 rs8067882 chr17:18807131 A/G cg04702396 chr17:15466718 FAM18B2 0.41 6.34 0.32 7.13e-10 Educational attainment (years of education); LIHC cis rs58785573 0.570 rs4833078 chr4:38646476 C/G cg18361445 chr4:38666374 KLF3;FLJ13197 0.51 7.22 0.36 3.42e-12 Lymphocyte percentage of white cells; LIHC cis rs58904263 1 rs58904263 chr20:30401406 A/AG cg13852791 chr20:30311386 BCL2L1 0.94 9.52 0.46 3.19e-19 Monocyte count; LIHC cis rs3806843 1.000 rs3756339 chr5:140180537 A/G cg26395211 chr5:140044315 WDR55 -0.43 -6.46 -0.33 3.65e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs7927771 0.832 rs10769258 chr11:47391039 C/T cg20135002 chr11:47629003 NA 0.5 8.56 0.42 3.81e-16 Subjective well-being; LIHC cis rs75908454 1.000 rs78513499 chr6:169964843 A/C cg19338460 chr6:170058176 WDR27 -0.83 -7.48 -0.38 6.2800000000000005e-13 Response to anti-TNF therapy in rheumatoid arthritis; LIHC cis rs858239 0.539 rs10280815 chr7:23188370 A/C cg23682824 chr7:23144976 KLHL7 0.46 6.96 0.35 1.71e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg02034447 chr16:89574710 SPG7 0.45 6.81 0.35 4.5e-11 Multiple myeloma (IgH translocation); LIHC cis rs7772486 0.790 rs9497425 chr6:146234197 G/A cg23711669 chr6:146136114 FBXO30 -0.62 -10.87 -0.51 7.96e-24 Lobe attachment (rater-scored or self-reported); LIHC cis rs2070488 0.574 rs57754356 chr3:38488706 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.75 12.5 0.56 9.07e-30 Electrocardiographic conduction measures; LIHC cis rs67311347 1.000 rs7617989 chr3:40512463 A/G cg18306943 chr3:40428807 ENTPD3 -0.37 -6.5 -0.33 2.83e-10 Renal cell carcinoma; LIHC cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.78 6.88 0.35 2.89e-11 Platelet count; LIHC trans rs1814175 0.645 rs1721997 chr11:49916653 T/C cg18944383 chr4:111397179 ENPEP 0.27 6.86 0.35 3.28e-11 Height; LIHC cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs68170813 0.559 rs11764448 chr7:106924928 A/G cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg19635926 chr16:89946313 TCF25 0.56 7.58 0.38 3.24e-13 Skin colour saturation; LIHC cis rs1559088 0.576 rs11084707 chr19:33612873 C/T cg03563238 chr19:33554763 RHPN2 -0.31 -5.75 -0.3 2.02e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs11098699 0.821 rs2099955 chr4:124214160 C/T cg09941581 chr4:124220074 SPATA5 0.32 6.48 0.33 3.25e-10 Mosquito bite size; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg07449447 chr14:55228808 SAMD4A -0.45 -6.51 -0.33 2.75e-10 Lung function (FEV1/FVC); LIHC cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.02 12.68 0.57 1.91e-30 Alzheimer's disease; LIHC cis rs10791097 0.668 rs10791102 chr11:130744977 G/A cg22079354 chr11:130786696 SNX19 0.42 6.04 0.31 3.96e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs780096 0.526 rs780107 chr2:27684734 A/G cg22903471 chr2:27725779 GCKR -0.5 -8.56 -0.42 3.89e-16 Total body bone mineral density; LIHC cis rs11792861 0.962 rs72607161 chr9:111792640 T/C cg05043794 chr9:111880884 C9orf5 -0.3 -7.01 -0.35 1.3e-11 Menarche (age at onset); LIHC cis rs11864453 1.000 rs11864453 chr16:72050480 C/T cg16558253 chr16:72132732 DHX38 -0.42 -5.9 -0.3 8.9e-9 Fibrinogen levels; LIHC cis rs4319547 0.695 rs4758648 chr12:122900460 A/G cg05707623 chr12:122985044 ZCCHC8 -0.5 -6.5 -0.33 2.78e-10 Body mass index; LIHC cis rs7945705 0.902 rs2016942 chr11:8938787 A/G cg12365402 chr11:9010492 NRIP3 0.31 7.95 0.39 2.76e-14 Hemoglobin concentration; LIHC cis rs17401966 0.838 rs12132134 chr1:10378428 A/G cg15208524 chr1:10270712 KIF1B 0.38 5.81 0.3 1.42e-8 Hepatocellular carcinoma; LIHC cis rs2153535 0.580 rs1328862 chr6:8526681 A/T cg07606381 chr6:8435919 SLC35B3 0.79 11.57 0.53 2.35e-26 Motion sickness; LIHC cis rs9303401 0.659 rs34468504 chr17:56648277 C/T cg25039879 chr17:56429692 SUPT4H1 0.78 8.89 0.43 3.6e-17 Cognitive test performance; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg18306943 chr3:40428807 ENTPD3 0.4 7.2 0.36 3.77e-12 Renal cell carcinoma; LIHC cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg03517284 chr6:25882590 NA -0.7 -8.77 -0.43 8.34e-17 Intelligence (multi-trait analysis); LIHC cis rs7945705 0.875 rs2653616 chr11:8885892 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -9.35 -0.45 1.22e-18 Hemoglobin concentration; LIHC cis rs80282103 0.618 rs17155886 chr10:1145182 A/G cg08668510 chr10:1095578 IDI1 0.62 6.05 0.31 3.89e-9 Glomerular filtration rate (creatinine); LIHC cis rs10832963 1.000 rs2084220 chr11:18656932 C/T cg09201001 chr11:18656081 SPTY2D1 0.93 17.09 0.68 8.8e-48 Breast cancer; LIHC trans rs5756813 0.754 rs4821706 chr22:38154690 A/G cg19894588 chr14:64061835 NA -0.64 -8.67 -0.42 1.8e-16 Optic cup area;Vertical cup-disc ratio; LIHC cis rs317689 0.684 rs315125 chr12:69758884 C/T cg20891283 chr12:69753455 YEATS4 0.69 10.94 0.51 4.41e-24 Response to diuretic therapy; LIHC cis rs611744 0.647 rs12675265 chr8:109268805 C/T cg18478394 chr8:109455254 TTC35 0.42 7.21 0.36 3.52e-12 Dupuytren's disease; LIHC trans rs7693389 0.925 rs2899092 chr4:58450181 A/G cg13593275 chr9:128777788 NA 0.53 6.05 0.31 3.87e-9 Diisocyanate-induced asthma; LIHC cis rs9790314 1.000 rs6775627 chr3:160953609 A/G cg03342759 chr3:160939853 NMD3 -0.72 -8.75 -0.43 1.01e-16 Morning vs. evening chronotype; LIHC cis rs12586317 0.620 rs12437439 chr14:35585669 C/A cg16230307 chr14:35515116 FAM177A1 0.78 12.97 0.57 1.51e-31 Psoriasis; LIHC cis rs9768139 0.733 rs71545585 chr7:158118672 G/A cg25566285 chr7:158114605 PTPRN2 0.22 5.99 0.31 5.44e-9 Calcium levels; LIHC cis rs1395 0.744 rs62130714 chr2:27532870 A/G cg17158414 chr2:27665306 KRTCAP3 -0.49 -5.87 -0.3 1.05e-8 Blood metabolite levels; LIHC cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg25364880 chr3:44379878 C3orf23 0.56 7.86 0.39 5.16e-14 Depressive symptoms; LIHC cis rs7520050 0.902 rs4626927 chr1:46248645 C/T cg03146154 chr1:46216737 IPP -0.41 -6.78 -0.34 5.34e-11 Red blood cell count;Reticulocyte count; LIHC cis rs68170813 0.559 rs17427158 chr7:106824259 G/T cg02696742 chr7:106810147 HBP1 -0.52 -6.07 -0.31 3.38e-9 Coronary artery disease; LIHC cis rs8058578 1.000 rs8048448 chr16:30692208 T/C cg00531865 chr16:30841666 NA -0.39 -6.09 -0.31 2.99e-9 Multiple myeloma; LIHC cis rs9503598 0.502 rs6917962 chr6:3430191 A/T cg00476032 chr6:3446245 SLC22A23 -0.32 -5.86 -0.3 1.08e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); LIHC cis rs1000083 0.748 rs2643523 chr5:96624676 A/G ch.5.96698337R chr5:96672581 NA -0.96 -7.29 -0.37 2.23e-12 Cisplatin-induced ototoxicity; LIHC cis rs2286885 1.000 rs10733679 chr9:129242416 C/T cg15282417 chr9:129245246 FAM125B 0.4 6.7 0.34 8.84e-11 Intraocular pressure; LIHC cis rs7208859 0.673 rs73277978 chr17:29191449 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9733 0.596 rs7549795 chr1:150656873 G/A cg13175981 chr1:150552382 MCL1 -0.44 -6.06 -0.31 3.56e-9 Tonsillectomy; LIHC cis rs2479724 0.870 rs3747753 chr6:41753380 G/T cg17623882 chr6:41773611 USP49 0.56 8.84 0.43 5.16e-17 Menarche (age at onset); LIHC cis rs34779708 0.931 rs2001893 chr10:35300623 G/A cg03585969 chr10:35415529 CREM 0.78 11.78 0.54 4.13e-27 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1198872 0.526 rs57282335 chr2:10928207 G/A cg10157359 chr2:10953004 PDIA6 -0.5 -6.76 -0.34 5.86e-11 Cardiac Troponin-T levels; LIHC cis rs8010715 0.804 rs1134334 chr14:24594114 A/G cg23112188 chr14:24563095 PCK2 -0.29 -6.04 -0.31 4.13e-9 IgG glycosylation; LIHC cis rs881827 0.851 rs55863940 chr21:48011048 A/T cg12379764 chr21:47803548 PCNT -0.43 -5.71 -0.3 2.42e-8 Lymphocyte counts; LIHC cis rs6942756 1.000 rs56026912 chr7:128913937 A/G cg02491457 chr7:128862824 NA -0.66 -10.4 -0.49 3.2800000000000002e-22 White matter hyperintensity burden; LIHC cis rs6089584 0.888 rs2386555 chr20:60612373 C/T cg06108461 chr20:60628389 TAF4 -1.01 -17.29 -0.68 1.41e-48 Body mass index; LIHC cis rs5758511 0.596 rs55644935 chr22:42666069 A/G cg20195005 chr22:42527684 CYP2D6 0.3 5.77 0.3 1.77e-8 Birth weight; LIHC cis rs11148252 0.553 rs9536219 chr13:53227301 C/T cg12458913 chr13:53173898 NA 0.47 7.48 0.37 6.36e-13 Lewy body disease; LIHC cis rs12188164 0.543 rs2434695 chr5:464177 C/G cg07599136 chr5:415885 AHRR 0.38 6.47 0.33 3.38e-10 Cystic fibrosis severity; LIHC cis rs798554 0.679 rs11973498 chr7:2886873 C/A cg13628971 chr7:2884303 GNA12 0.6 10.21 0.48 1.5e-21 Height; LIHC cis rs1550582 0.662 rs7812708 chr8:135500832 C/T cg17885191 chr8:135476712 NA 0.46 8.14 0.4 7.28e-15 Educational attainment; LIHC cis rs10861661 0.963 rs10861669 chr12:107200068 C/A cg15890332 chr12:107067104 RFX4 0.26 5.76 0.3 1.84e-8 Triglyceride levels; LIHC cis rs225245 0.791 rs720774 chr17:34017453 T/G cg05299278 chr17:33885742 SLFN14 0.23 6.34 0.32 7.13e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs6686842 0.562 rs18996 chr1:41624520 C/T cg08462924 chr1:41848221 NA 0.32 5.89 0.3 9.23e-9 Height; LIHC cis rs8103278 1.000 rs725660 chr19:46262286 C/A cg11657440 chr19:46296263 DMWD -0.55 -8.81 -0.43 6.37e-17 Coronary artery disease; LIHC cis rs807029 0.533 rs2295716 chr10:102744214 T/C cg25179470 chr10:102756915 LZTS2 0.45 6.38 0.33 5.65e-10 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg10130564 chr11:117069849 TAGLN 0.36 6.1 0.31 2.95e-9 Blood protein levels; LIHC cis rs4919087 0.748 rs1147600 chr10:98981643 T/C cg25902810 chr10:99078978 FRAT1 -0.56 -6.39 -0.33 5.39e-10 Monocyte count; LIHC cis rs7172677 0.768 rs72730585 chr15:75353906 A/G cg09165964 chr15:75287851 SCAMP5 0.52 7.46 0.37 7.34e-13 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs6450176 0.564 rs390420 chr5:53326731 G/A ch.5.1024479R chr5:53302184 ARL15 -0.75 -13.51 -0.59 1.27e-33 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2073300 0.609 rs6137951 chr20:23429459 T/C cg16736954 chr20:23401023 NAPB 0.71 8.28 0.41 2.77e-15 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs2629540 0.847 rs12763093 chr10:126395688 C/G cg08799069 chr10:126477246 METTL10 -0.46 -7.2 -0.36 3.79e-12 Cocaine dependence; LIHC cis rs9921222 0.500 rs12917907 chr16:405866 C/T cg12437481 chr16:420112 MRPL28 -0.67 -9.55 -0.46 2.67e-19 Bone mineral density (spine);Bone mineral density; LIHC cis rs4423214 1.000 rs11600860 chr11:71164019 T/C cg24826892 chr11:71159390 DHCR7 0.51 6.57 0.33 1.92e-10 Vitamin D levels; LIHC trans rs2243480 1.000 rs4718317 chr7:65648901 A/G cg10756647 chr7:56101905 PSPH -1.02 -12.92 -0.57 2.19e-31 Diabetic kidney disease; LIHC cis rs10464366 0.614 rs62442213 chr7:39146933 C/T cg20302533 chr7:39170763 POU6F2 0.37 6.7 0.34 8.44e-11 IgG glycosylation; LIHC cis rs12701220 0.847 rs10272002 chr7:1047615 A/G cg00990874 chr7:1149470 C7orf50 -0.7 -9.81 -0.47 3.39e-20 Bronchopulmonary dysplasia; LIHC cis rs7772486 0.738 rs2246334 chr6:146183635 G/A cg23711669 chr6:146136114 FBXO30 0.72 13.24 0.58 1.38e-32 Lobe attachment (rater-scored or self-reported); LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg03929569 chr13:30689009 NA 0.49 6.09 0.31 3.1e-9 Hepatitis; LIHC cis rs7940866 0.774 rs7480903 chr11:130832276 A/G cg12179176 chr11:130786555 SNX19 0.6 8.68 0.43 1.59e-16 Schizophrenia; LIHC cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg05368731 chr17:41323189 NBR1 0.72 12.29 0.55 5.32e-29 Menopause (age at onset); LIHC cis rs6500602 0.727 rs12443748 chr16:4541831 C/T cg08645402 chr16:4508243 NA 0.43 7.89 0.39 4.07e-14 Schizophrenia; LIHC cis rs9300255 0.602 rs1716165 chr12:123648881 C/T cg00376283 chr12:123451042 ABCB9 0.66 7.56 0.38 3.84e-13 Neutrophil percentage of white cells; LIHC cis rs7224314 0.895 rs11654663 chr17:65389305 A/C cg01507342 chr17:65387096 PITPNC1 -0.5 -6.54 -0.33 2.26e-10 Diisocyanate-induced asthma; LIHC cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg11062466 chr8:58055876 NA 0.4 5.82 0.3 1.36e-8 Developmental language disorder (linguistic errors); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20586607 chr14:50235780 KLHDC2 0.4 6.06 0.31 3.51e-9 Cognitive function; LIHC cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg08677398 chr8:58056175 NA 0.4 6.24 0.32 1.3e-9 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg10360323 chr17:41437877 NA 0.41 6.12 0.31 2.53e-9 Menopause (age at onset); LIHC cis rs11212260 0.655 rs10458952 chr11:107292898 C/T cg25435332 chr11:107328525 CWF19L2 0.8 8.13 0.4 7.75e-15 IgG glycosylation; LIHC cis rs4988958 0.565 rs3755265 chr2:103052816 C/A cg03938978 chr2:103052716 IL18RAP 0.3 5.9 0.3 8.77e-9 Asthma (childhood onset); LIHC cis rs6733011 0.628 rs6713991 chr2:99464384 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.42 -5.83 -0.3 1.27e-8 Bipolar disorder; LIHC cis rs2412488 0.861 rs10000746 chr4:54281731 T/A cg22241045 chr4:54363911 LNX1 -0.47 -7.51 -0.38 5.16e-13 DNA methylation (variation); LIHC cis rs12594515 1.000 rs7162201 chr15:45992658 A/C cg19682013 chr15:45996608 NA 0.39 6.67 0.34 1.01e-10 Waist circumference;Weight; LIHC trans rs1347297 0.789 rs11688081 chr2:179280799 A/G cg14011486 chr1:26737247 LIN28 0.44 6.84 0.35 3.6e-11 Alzheimer disease and age of onset; LIHC trans rs61931739 0.500 rs10844864 chr12:34532468 A/G cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs3008870 0.755 rs1024229 chr1:67512903 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.51 8.89 0.43 3.61e-17 Lymphocyte percentage of white cells; LIHC cis rs9640161 0.658 rs60467296 chr7:150015471 G/A cg17279839 chr7:150038598 RARRES2 0.48 10.1 0.48 3.59e-21 Blood protein levels;Circulating chemerin levels; LIHC cis rs763121 0.853 rs2281019 chr22:39064378 T/A cg06022373 chr22:39101656 GTPBP1 0.64 11.15 0.52 7.61e-25 Menopause (age at onset); LIHC cis rs77637988 0.578 rs7577237 chr2:48601816 A/G cg15846641 chr2:48541264 FOXN2 -0.59 -8.03 -0.4 1.54e-14 Joint mobility (Beighton score); LIHC cis rs711245 0.573 rs7570763 chr2:36800589 A/C cg01206211 chr2:36825736 FEZ2 -0.42 -6.87 -0.35 3.11e-11 Height; LIHC cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.87 7.92 0.39 3.45e-14 Platelet count; LIHC cis rs367615 0.704 rs55956735 chr5:108845042 A/G cg17395555 chr5:108820864 NA 0.4 8.8 0.43 7.12e-17 Colorectal cancer (SNP x SNP interaction); LIHC cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg13395646 chr4:1353034 KIAA1530 -0.67 -9.53 -0.46 3.04e-19 Obesity-related traits; LIHC cis rs748404 0.631 rs7167882 chr15:43678663 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.55 9.72 0.47 6.98e-20 Lung cancer; LIHC cis rs9393692 0.645 rs9467703 chr6:26318903 A/G cg00631329 chr6:26305371 NA -0.5 -7.78 -0.39 8.59e-14 Educational attainment; LIHC cis rs2153535 0.580 rs6421949 chr6:8531769 G/A cg23788917 chr6:8435910 SLC35B3 0.63 8.93 0.44 2.58e-17 Motion sickness; LIHC cis rs2739330 0.929 rs5751775 chr22:24266726 T/C cg09033563 chr22:24373618 LOC391322 -0.46 -6.39 -0.33 5.45e-10 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7208859 0.623 rs57486336 chr17:29085731 G/T cg13385521 chr17:29058706 SUZ12P 0.82 8.13 0.4 8.11e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7666738 0.830 rs11097582 chr4:98772201 G/A cg05340658 chr4:99064831 C4orf37 0.63 11.52 0.53 3.68e-26 Colonoscopy-negative controls vs population controls; LIHC cis rs4891159 0.548 rs690414 chr18:74117840 T/C cg24786174 chr18:74118243 ZNF516 0.85 17.56 0.69 1.19e-49 Longevity; LIHC cis rs4684776 0.935 rs11128547 chr3:11393268 A/G cg00170343 chr3:11313890 ATG7 0.5 6.84 0.35 3.75e-11 Small vessel stroke; LIHC cis rs4268898 0.636 rs72787385 chr2:24585820 G/A cg06627628 chr2:24431161 ITSN2 -0.74 -9.65 -0.46 1.22e-19 Asthma; LIHC cis rs9368481 0.761 rs6918835 chr6:27017827 T/G cg18867708 chr6:26865862 GUSBL1 -0.54 -8.2 -0.41 4.83e-15 Autism spectrum disorder or schizophrenia; LIHC cis rs57590327 0.503 rs6764261 chr3:81620370 T/G cg07356753 chr3:81810745 GBE1 -0.56 -8.57 -0.42 3.51e-16 Extraversion; LIHC cis rs760805 1.000 rs11249204 chr1:25261740 C/T cg22509179 chr1:25234806 RUNX3 0.38 8.13 0.4 8.22e-15 Allergic disease (asthma, hay fever or eczema); LIHC cis rs929354 0.713 rs7798816 chr7:156940574 A/G cg05182265 chr7:156933206 UBE3C -0.31 -5.84 -0.3 1.22e-8 Body mass index; LIHC trans rs7193541 0.684 rs7191665 chr16:74688948 T/G cg23598604 chr1:99732472 LPPR4 -0.3 -6.27 -0.32 1.09e-9 Multiple myeloma; LIHC cis rs727505 1.000 rs59294613 chr7:124554267 C/A cg23710748 chr7:124431027 NA -0.33 -5.9 -0.3 8.64e-9 Lewy body disease; LIHC cis rs8067354 0.574 rs1296279 chr17:57965731 G/A cg02344993 chr17:57696989 CLTC 0.66 10.3 0.49 7.37e-22 Hemoglobin concentration; LIHC cis rs986417 0.901 rs713449 chr14:61029084 C/G cg27398547 chr14:60952738 C14orf39 0.7 7.43 0.37 8.8e-13 Gut microbiota (bacterial taxa); LIHC cis rs870825 0.616 rs4623061 chr4:185643161 A/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs6450176 1.000 rs4334835 chr5:53300612 T/G ch.5.1024479R chr5:53302184 ARL15 -0.81 -14.59 -0.62 8.14e-38 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6728642 0.572 rs1320147 chr2:97600626 A/C cg26665480 chr2:98280029 ACTR1B 0.5 6.29 0.32 9.68e-10 Bipolar disorder lithium response (continuous) or schizophrenia; LIHC cis rs13096760 1 rs13096760 chr3:49476806 T/C cg06212747 chr3:49208901 KLHDC8B 0.47 6.12 0.31 2.51e-9 Intelligence (multi-trait analysis); LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg05896524 chr21:47604654 C21orf56 0.51 8.17 0.4 6.2e-15 Testicular germ cell tumor; LIHC cis rs7937682 0.575 rs34558891 chr11:111737912 C/T cg09085632 chr11:111637200 PPP2R1B 0.96 13.88 0.6 4.81e-35 Primary sclerosing cholangitis; LIHC cis rs6912958 0.559 rs173333 chr6:88047754 T/G cg12350822 chr6:88032061 C6orf162;GJB7 0.37 7.32 0.37 1.74e-12 Monocyte percentage of white cells; LIHC cis rs7904368 0.754 rs11254231 chr10:16870246 A/G cg14835575 chr10:16859367 RSU1 0.64 8.63 0.42 2.33e-16 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; LIHC cis rs7520050 0.966 rs4660898 chr1:46402171 A/G cg03146154 chr1:46216737 IPP -0.38 -6.25 -0.32 1.21e-9 Red blood cell count;Reticulocyte count; LIHC cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg08219700 chr8:58056026 NA 0.53 7.17 0.36 4.67e-12 Developmental language disorder (linguistic errors); LIHC cis rs506338 0.517 rs17146216 chr11:64451281 C/G cg27209729 chr11:64428925 NRXN2 0.36 6.76 0.34 6.06e-11 Body mass index;Urate levels; LIHC cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg04287289 chr16:89883240 FANCA 0.54 8.64 0.42 2.15e-16 Vitiligo; LIHC cis rs10504229 0.679 rs16921676 chr8:58052386 G/T cg02290350 chr8:58132656 NA 0.32 7.02 0.35 1.23e-11 Developmental language disorder (linguistic errors); LIHC cis rs4253772 0.550 rs6008729 chr22:46727428 C/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.68 -5.9 -0.3 8.63e-9 LDL cholesterol;Cholesterol, total; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg15715256 chr5:42767749 CCDC152 -0.42 -6.36 -0.33 6.3e-10 Hepatitis; LIHC cis rs4803468 0.967 rs3745290 chr19:41890003 C/T cg09537434 chr19:41945824 ATP5SL -0.99 -20.12 -0.74 5.95e-60 Height; LIHC cis rs600806 0.683 rs10857788 chr1:110012289 G/A cg16275483 chr1:110013120 SYPL2 -0.49 -6.08 -0.31 3.2e-9 Intelligence (multi-trait analysis); LIHC cis rs72781680 0.898 rs113027486 chr2:24098371 G/A cg08917208 chr2:24149416 ATAD2B 0.91 8.41 0.41 1.14e-15 Lymphocyte counts; LIHC cis rs11018874 0.597 rs10765243 chr11:89855118 C/G cg05041596 chr11:89867385 NAALAD2 0.43 7.11 0.36 6.87e-12 White blood cell types; LIHC cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.51 0.62 1.6e-37 Prudent dietary pattern; LIHC cis rs614226 0.744 rs787832 chr12:120986801 A/G cg01236616 chr12:121019343 POP5 1.24 19.05 0.72 1.14e-55 Type 1 diabetes nephropathy; LIHC cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg05590025 chr7:65112418 INTS4L2 -0.63 -7.04 -0.36 1.08e-11 Diabetic kidney disease; LIHC cis rs1816752 0.905 rs13428 chr13:25009441 C/G cg02811702 chr13:24901961 NA 0.25 6.33 0.32 7.79e-10 Obesity-related traits; LIHC cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg25072359 chr17:41440525 NA 0.37 5.99 0.31 5.46e-9 Menopause (age at onset); LIHC cis rs4555082 0.834 rs2816631 chr14:105739477 G/A cg13114125 chr14:105738426 BRF1 -0.79 -10.09 -0.48 4e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs35306767 0.903 rs12778891 chr10:950130 T/A cg26597838 chr10:835615 NA 1.13 13.86 0.6 5.46e-35 Eosinophil percentage of granulocytes; LIHC cis rs6977660 1.000 rs34367208 chr7:19818811 T/G cg07541023 chr7:19748670 TWISTNB 0.37 5.87 0.3 1.01e-8 Thyroid stimulating hormone; LIHC cis rs10242455 0.571 rs80045298 chr7:99307453 T/A cg18809830 chr7:99032528 PTCD1 -0.86 -6.71 -0.34 8.19e-11 Blood metabolite levels; LIHC cis rs13217239 0.646 rs12523820 chr6:27001502 A/G cg18867708 chr6:26865862 GUSBL1 0.52 8.03 0.4 1.64e-14 Schizophrenia; LIHC cis rs769267 0.501 rs2965187 chr19:19522970 T/A cg03709012 chr19:19516395 GATAD2A 0.64 7.1 0.36 7.14e-12 Tonsillectomy; LIHC cis rs9921222 0.509 rs3743883 chr16:404750 T/C cg26944245 chr16:421049 TMEM8A;MRPL28 0.54 11.0 0.51 2.69e-24 Bone mineral density (spine);Bone mineral density; LIHC cis rs7903847 0.642 rs7078004 chr10:99140511 A/G cg06359132 chr10:99160096 RRP12 -0.42 -6.52 -0.33 2.52e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg04944784 chr2:26401820 FAM59B -0.74 -9.26 -0.45 2.25e-18 Gut microbiome composition (summer); LIHC cis rs9457247 0.612 rs2237273 chr6:167443017 T/C cg07741184 chr6:167504864 NA 0.26 5.97 0.31 5.91e-9 Crohn's disease; LIHC cis rs8062405 1.000 rs7498665 chr16:28883241 A/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg10348368 chr14:105851883 PACS2 0.41 6.17 0.32 1.91e-9 Longevity; LIHC cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg04234412 chr22:24373322 LOC391322 -0.72 -11.26 -0.52 3.21e-25 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg10802521 chr3:52805072 NEK4 -0.43 -7.02 -0.36 1.17e-11 Bipolar disorder; LIHC cis rs10927875 0.619 rs7537101 chr1:16150384 T/C cg21385522 chr1:16154831 NA -0.75 -10.88 -0.51 6.94e-24 Dilated cardiomyopathy; LIHC cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg02353165 chr6:42928485 GNMT 0.73 11.11 0.51 1.08e-24 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs6835098 0.509 rs2332655 chr4:174093002 A/G cg27433088 chr4:174089019 GALNT7 -0.33 -6.24 -0.32 1.3e-9 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs2153535 0.563 rs4428546 chr6:8490376 A/G cg21535247 chr6:8435926 SLC35B3 0.6 7.85 0.39 5.26e-14 Motion sickness; LIHC cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg18230493 chr5:56204884 C5orf35 -0.46 -6.39 -0.33 5.56e-10 Initial pursuit acceleration; LIHC cis rs1005277 0.579 rs1740742 chr10:38518860 C/T cg18963800 chr10:38644991 HSD17B7P2 -0.42 -6.21 -0.32 1.52e-9 Extrinsic epigenetic age acceleration; LIHC cis rs4638749 0.677 rs17035849 chr2:108842593 G/T cg25838818 chr2:108905173 SULT1C2 -0.39 -6.6 -0.34 1.6e-10 Blood pressure; LIHC cis rs9522267 0.535 rs9522291 chr13:112233761 T/C cg10483660 chr13:112241077 NA -0.21 -5.81 -0.3 1.39e-8 Hepatitis; LIHC cis rs6604026 0.555 rs11805007 chr1:93082190 A/G cg13858687 chr1:93297071 RPL5 0.6 5.71 0.3 2.41e-8 Multiple sclerosis; LIHC cis rs4665809 0.793 rs6546715 chr2:26261520 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.69 -8.45 -0.42 8.76e-16 Gut microbiome composition (summer); LIHC cis rs3008870 0.959 rs4655658 chr1:67389608 C/T cg02640540 chr1:67518911 SLC35D1 0.42 5.83 0.3 1.25e-8 Lymphocyte percentage of white cells; LIHC cis rs1712517 0.771 rs11191664 chr10:105118476 C/T cg05636881 chr10:105038444 INA 0.49 7.53 0.38 4.51e-13 Migraine; LIHC cis rs459571 0.959 rs465724 chr9:136910097 C/T cg13789015 chr9:136890014 NCRNA00094 0.42 7.58 0.38 3.32e-13 Platelet distribution width; LIHC cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg18225595 chr11:63971243 STIP1 0.62 7.73 0.39 1.25e-13 Mean platelet volume; LIHC cis rs11122272 0.735 rs2491410 chr1:231532287 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -10.98 -0.51 3.28e-24 Hemoglobin concentration; LIHC cis rs61712019 1.000 rs13420329 chr2:77706547 C/T cg11252801 chr2:77748917 LRRTM4 0.5 7.72 0.39 1.32e-13 Schizophrenia; LIHC cis rs15676 0.947 rs10988124 chr9:131569345 G/A cg13708974 chr9:131466143 PKN3 0.39 5.85 0.3 1.17e-8 Blood metabolite levels; LIHC cis rs9649465 0.561 rs603060 chr7:123427568 A/G cg03229431 chr7:123269106 ASB15 -0.44 -9.46 -0.46 5.01e-19 Migraine; LIHC cis rs600231 0.706 rs4244811 chr11:65320780 G/A cg13974409 chr11:65292307 SCYL1 -0.38 -5.99 -0.31 5.34e-9 Bone mineral density; LIHC cis rs600806 0.821 rs1030522 chr1:109900707 C/G cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.13 -0.31 2.45e-9 Intelligence (multi-trait analysis); LIHC cis rs56235845 0.694 rs6876677 chr5:176755342 T/C cg06060754 chr5:176797920 RGS14 0.48 6.75 0.34 6.43e-11 Hemoglobin concentration;Hematocrit; LIHC cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg25364880 chr3:44379878 C3orf23 0.6 8.45 0.42 8.37e-16 Depressive symptoms; LIHC cis rs7086627 0.515 rs10887899 chr10:82210214 G/A cg00277334 chr10:82204260 NA -0.85 -13.76 -0.6 1.3600000000000001e-34 Post bronchodilator FEV1; LIHC cis rs2806561 0.929 rs856508 chr1:23532995 A/C cg19743168 chr1:23544995 NA 0.43 7.94 0.39 2.93e-14 Height; LIHC cis rs6665290 0.835 rs7549586 chr1:227214566 A/G cg10327440 chr1:227177885 CDC42BPA -1.14 -22.14 -0.77 4.92e-68 Myeloid white cell count; LIHC cis rs2842992 0.750 rs2758354 chr6:160125854 A/G cg16489826 chr6:160211363 TCP1;MRPL18 0.57 9.89 0.47 1.8899999999999998e-20 Age-related macular degeneration (geographic atrophy); LIHC cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg27297192 chr10:134578999 INPP5A 0.53 7.32 0.37 1.74e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs4474465 0.790 rs4492845 chr11:78260161 C/T cg27205649 chr11:78285834 NARS2 0.43 6.71 0.34 8.04e-11 Alzheimer's disease (survival time); LIHC cis rs7116495 0.609 rs7113520 chr11:71691946 G/A cg26138937 chr11:71823887 C11orf51 -1.28 -10.0 -0.48 8.22e-21 Severe influenza A (H1N1) infection; LIHC cis rs2832191 0.933 rs2832236 chr21:30547602 C/T cg24692254 chr21:30365293 RNF160 -0.48 -8.15 -0.4 6.79e-15 Dental caries; LIHC cis rs611744 0.837 rs403200 chr8:109103375 C/T cg21045802 chr8:109455806 TTC35 0.47 8.11 0.4 8.87e-15 Dupuytren's disease; LIHC trans rs8002861 0.840 rs1819597 chr13:44429553 G/A cg17145862 chr1:211918768 LPGAT1 0.58 10.75 0.5 2.1e-23 Leprosy; LIHC cis rs4474465 0.688 rs4277140 chr11:78285096 G/T cg27205649 chr11:78285834 NARS2 -0.5 -7.91 -0.39 3.51e-14 Alzheimer's disease (survival time); LIHC cis rs992157 0.560 rs7605980 chr2:219100869 C/G cg00012203 chr2:219082015 ARPC2 0.86 14.85 0.63 7.6e-39 Colorectal cancer; LIHC cis rs9814567 1.000 rs7374325 chr3:134275601 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs9649465 0.967 rs10269196 chr7:123321073 G/T cg03229431 chr7:123269106 ASB15 -0.39 -8.37 -0.41 1.48e-15 Migraine; LIHC cis rs3936840 0.964 rs10150698 chr14:102977876 A/G cg10241871 chr14:102965420 TECPR2 -0.39 -6.13 -0.31 2.38e-9 Plateletcrit; LIHC trans rs17685 0.712 rs7785025 chr7:75628101 C/T cg19862616 chr7:65841803 NCRNA00174 -0.89 -17.84 -0.69 8.29e-51 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg17158414 chr2:27665306 KRTCAP3 -0.43 -5.92 -0.31 7.67e-9 Total body bone mineral density; LIHC cis rs888194 0.738 rs7298565 chr12:109937534 A/G cg05360138 chr12:110035743 NA -0.41 -5.88 -0.3 9.76e-9 Neuroticism; LIHC cis rs2153535 0.580 rs915352 chr6:8442766 G/A cg21535247 chr6:8435926 SLC35B3 0.61 7.95 0.39 2.79e-14 Motion sickness; LIHC cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg12756686 chr19:29218302 NA 0.43 6.64 0.34 1.24e-10 Methadone dose in opioid dependence; LIHC cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg11987759 chr7:65425863 GUSB -0.39 -6.11 -0.31 2.75e-9 Aortic root size; LIHC cis rs62179067 0.708 rs11891608 chr2:179940373 G/T cg07532576 chr2:179544947 TTN 0.64 5.79 0.3 1.61e-8 Late-onset Alzheimer's disease; LIHC cis rs11711311 1.000 rs12695295 chr3:113474866 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.41 7.95 0.39 2.74e-14 IgG glycosylation; LIHC cis rs35110281 0.807 rs28840140 chr21:45039163 T/C cg04455712 chr21:45112962 RRP1B 0.46 7.88 0.39 4.47e-14 Mean corpuscular volume; LIHC cis rs7903847 0.620 rs10882907 chr10:99125788 C/G cg06359132 chr10:99160096 RRP12 0.37 5.83 0.3 1.25e-8 Granulocyte percentage of myeloid white cells; LIHC cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg27297192 chr10:134578999 INPP5A 0.56 7.71 0.38 1.41e-13 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg20607798 chr8:58055168 NA 0.62 7.9 0.39 3.74e-14 Developmental language disorder (linguistic errors); LIHC cis rs611744 0.967 rs702801 chr8:109211802 T/C cg21045802 chr8:109455806 TTC35 0.51 8.82 0.43 5.8e-17 Dupuytren's disease; LIHC cis rs6815814 0.950 rs5743560 chr4:38806200 G/T cg06935464 chr4:38784597 TLR10 0.47 7.32 0.37 1.81e-12 Breast cancer; LIHC cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg25072359 chr17:41440525 NA 0.38 6.01 0.31 4.83e-9 Menopause (age at onset); LIHC cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg12311346 chr5:56204834 C5orf35 -0.57 -7.56 -0.38 3.86e-13 Initial pursuit acceleration; LIHC cis rs807669 1.000 rs807669 chr22:19154522 T/C cg02655711 chr22:19163373 SLC25A1 0.62 9.28 0.45 2.02e-18 Metabolite levels; LIHC cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg11766577 chr21:47581405 C21orf56 -0.45 -7.42 -0.37 9.16e-13 Testicular germ cell tumor; LIHC cis rs73001065 0.792 rs17216588 chr19:19664077 C/T cg03709012 chr19:19516395 GATAD2A 0.89 7.48 0.37 6.3e-13 LDL cholesterol; LIHC cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg25894440 chr7:65020034 NA -0.56 -6.49 -0.33 3.01e-10 Diabetic kidney disease; LIHC cis rs6570726 0.791 rs4335004 chr6:145904764 G/A cg23711669 chr6:146136114 FBXO30 0.73 12.62 0.56 3e-30 Lobe attachment (rater-scored or self-reported); LIHC trans rs3749237 0.929 rs62260715 chr3:49829326 G/A cg21659725 chr3:3221576 CRBN 0.82 12.52 0.56 7.26e-30 Resting heart rate; LIHC cis rs11168351 0.833 rs6580652 chr12:48447105 C/A cg21466736 chr12:48725269 NA 0.63 8.99 0.44 1.69e-17 Bipolar disorder and schizophrenia; LIHC cis rs858239 0.539 rs3950345 chr7:23191114 T/C cg23682824 chr7:23144976 KLHL7 0.46 6.83 0.35 3.89e-11 Cerebrospinal fluid biomarker levels; LIHC trans rs1814175 0.817 rs7109440 chr11:49966296 C/T cg03929089 chr4:120376271 NA -0.89 -18.22 -0.7 2.49e-52 Height; LIHC cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg02931644 chr1:25747376 RHCE 0.38 8.45 0.42 8.49e-16 Plateletcrit;Mean corpuscular volume; LIHC trans rs3942852 0.726 rs10742836 chr11:48175831 G/A cg03929089 chr4:120376271 NA -0.56 -7.62 -0.38 2.6e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs5769765 0.837 rs7284417 chr22:50314346 A/G cg26441486 chr22:50317300 CRELD2 0.35 6.25 0.32 1.19e-9 Schizophrenia; LIHC cis rs9926296 0.593 rs6500456 chr16:89888341 T/C cg04287289 chr16:89883240 FANCA 0.53 8.44 0.42 8.92e-16 Vitiligo; LIHC trans rs6906287 0.625 rs9320649 chr6:118693665 A/G cg08164852 chr1:28844593 SNHG3-RCC1;RCC1 0.4 6.13 0.31 2.37e-9 Electrocardiographic conduction measures; LIHC cis rs17685 0.712 rs1859794 chr7:75821544 G/A cg16684958 chr7:75615977 POR 0.48 8.13 0.4 8.21e-15 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35110281 0.807 rs6518301 chr21:45016818 T/C cg01579765 chr21:45077557 HSF2BP -0.34 -6.48 -0.33 3.21e-10 Mean corpuscular volume; LIHC trans rs61931739 0.500 rs9669027 chr12:34583528 C/T cg26384229 chr12:38710491 ALG10B -0.62 -7.76 -0.39 1.01e-13 Morning vs. evening chronotype; LIHC cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.72 11.45 0.53 6.46e-26 Prudent dietary pattern; LIHC trans rs10506458 0.915 rs60094497 chr12:63394838 T/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.75 -10.68 -0.5 3.56e-23 Hemostatic factors and hematological phenotypes; LIHC cis rs12701220 0.522 rs12334290 chr7:1054517 A/G cg16145915 chr7:1198662 ZFAND2A -0.27 -5.74 -0.3 2.11e-8 Bronchopulmonary dysplasia; LIHC cis rs8141529 0.732 rs2239815 chr22:29192670 C/T cg02153584 chr22:29168773 CCDC117 -0.56 -9.11 -0.44 7e-18 Lymphocyte counts; LIHC cis rs735860 0.674 rs209485 chr6:53174448 C/T cg10236188 chr6:53219634 NA -0.4 -7.5 -0.38 5.67e-13 Glaucoma; LIHC cis rs17106184 0.892 rs58836765 chr1:50896037 G/A cg07174182 chr1:51127561 FAF1 -0.57 -6.36 -0.33 6.33e-10 Type 2 diabetes; LIHC cis rs249954 0.512 rs27770 chr16:23701538 A/G cg05131483 chr16:23706242 ERN2 0.36 5.84 0.3 1.23e-8 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs870825 1.000 rs9995633 chr4:185584441 C/T cg04058563 chr4:185651563 MLF1IP 0.65 5.73 0.3 2.22e-8 Blood protein levels; LIHC cis rs754466 0.512 rs67607593 chr10:79649050 A/G cg17075019 chr10:79541650 NA -0.75 -11.06 -0.51 1.67e-24 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9612 1.000 rs347519 chr19:44273516 T/C cg08581076 chr19:44259116 C19orf61 0.59 7.46 0.37 7.17e-13 Exhaled nitric oxide output; LIHC cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg19729930 chr2:74357872 NA 0.79 17.49 0.69 2.24e-49 Gestational age at birth (maternal effect); LIHC cis rs2637266 1.000 rs7080883 chr10:78361200 A/G cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.96e-9 Pulmonary function; LIHC cis rs10751667 0.621 rs4075990 chr11:976614 T/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs12365397 0.775 rs1874435 chr11:43246675 A/G cg16667275 chr11:43333495 API5 -0.41 -6.21 -0.32 1.57e-9 Migraine; LIHC cis rs66573146 0.561 rs67245546 chr4:6947164 T/C cg00086871 chr4:6988644 TBC1D14 0.87 6.22 0.32 1.48e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs2404602 1.000 rs12148786 chr15:76800362 A/G cg23625390 chr15:77176239 SCAPER 0.41 6.87 0.35 2.98e-11 Blood metabolite levels; LIHC cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg08132940 chr7:1081526 C7orf50 -0.79 -6.68 -0.34 9.73e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg00684032 chr4:1343700 KIAA1530 0.39 6.67 0.34 1.04e-10 Obesity-related traits; LIHC cis rs12497850 0.897 rs6781790 chr3:49044767 C/T cg07636037 chr3:49044803 WDR6 0.94 17.31 0.68 1.22e-48 Parkinson's disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg11954230 chr10:105677556 OBFC1 0.43 6.38 0.33 5.63e-10 Cognitive function; LIHC cis rs4423214 1.000 rs12422045 chr11:71154820 C/T cg24826892 chr11:71159390 DHCR7 0.51 6.64 0.34 1.22e-10 Vitamin D levels; LIHC cis rs9790314 1.000 rs336543 chr3:161061080 C/T cg04691961 chr3:161091175 C3orf57 0.43 6.94 0.35 2.03e-11 Morning vs. evening chronotype; LIHC cis rs12824058 0.831 rs12829373 chr12:130814114 G/C cg26677194 chr12:130822605 PIWIL1 0.51 7.17 0.36 4.52e-12 Menopause (age at onset); LIHC cis rs11792861 0.525 rs2417975 chr9:111860185 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.45 6.55 0.33 2.1e-10 Menarche (age at onset); LIHC cis rs1707322 1.000 rs10789486 chr1:46408667 A/G cg03146154 chr1:46216737 IPP 0.48 8.04 0.4 1.46e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg19774624 chr17:42201019 HDAC5 -0.81 -12.7 -0.57 1.48e-30 Total body bone mineral density; LIHC cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg05590025 chr7:65112418 INTS4L2 -0.66 -7.2 -0.36 3.94e-12 Diabetic kidney disease; LIHC cis rs2991971 0.934 rs7903 chr1:45976472 G/C cg15605315 chr1:45957053 TESK2 0.49 6.72 0.34 7.44e-11 High light scatter reticulocyte count; LIHC cis rs12477438 0.501 rs7349217 chr2:99815146 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.18 21.09 0.75 7.35e-64 Chronic sinus infection; LIHC cis rs7044106 0.734 rs1981020 chr9:123388464 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.68 10.57 0.5 8.87e-23 Hip circumference adjusted for BMI; LIHC cis rs17401966 1.000 rs6700866 chr1:10306038 A/G cg15208524 chr1:10270712 KIF1B 0.44 6.42 0.33 4.49e-10 Hepatocellular carcinoma; LIHC cis rs3540 0.618 rs11636089 chr15:91039527 C/T cg22089800 chr15:90895588 ZNF774 0.6 8.34 0.41 1.9e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs8062405 1.000 rs56404918 chr16:28846840 T/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg08280861 chr8:58055591 NA 0.49 6.06 0.31 3.57e-9 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC cis rs16912285 0.636 rs7114960 chr11:24310828 G/A ch.11.24196551F chr11:24239977 NA 0.76 10.01 0.48 7.41e-21 Visceral adipose tissue/subcutaneous adipose tissue ratio; LIHC cis rs9473924 0.505 rs55653665 chr6:50812984 T/C cg14470998 chr6:50812995 TFAP2B 0.98 11.38 0.52 1.19e-25 Body mass index; LIHC cis rs9467773 1.000 rs9461271 chr6:26554968 G/A cg11502198 chr6:26597334 ABT1 0.45 6.57 0.33 1.85e-10 Intelligence (multi-trait analysis); LIHC cis rs2629540 0.847 rs11245342 chr10:126414084 C/T cg20435097 chr10:126320824 FAM53B -0.44 -6.58 -0.34 1.81e-10 Cocaine dependence; LIHC cis rs116095464 0.558 rs6555055 chr5:226160 A/C cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18652121 chr3:179322868 MRPL47;NDUFB5 0.45 6.84 0.35 3.59e-11 Cognitive function; LIHC cis rs1577917 1.000 rs12201735 chr6:86656939 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.59 -10.24 -0.48 1.23e-21 Response to antipsychotic treatment; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg00185336 chr7:73153699 ABHD11 0.41 6.58 0.34 1.79e-10 Cognitive function; LIHC cis rs3768617 0.510 rs3768620 chr1:183092237 G/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.58 0.5 8.13e-23 Fuchs's corneal dystrophy; LIHC cis rs9303401 0.659 rs62083362 chr17:56846464 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.9 12.19 0.55 1.22e-28 Cognitive test performance; LIHC cis rs939574 1.000 rs2293078 chr2:220100683 C/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.02 10.72 0.5 2.59e-23 Platelet distribution width; LIHC cis rs13217239 0.646 rs10946891 chr6:26973215 T/C cg12292205 chr6:26970375 C6orf41 0.45 7.76 0.39 1.02e-13 Schizophrenia; LIHC cis rs6191 0.844 rs258763 chr5:142652361 T/A cg17617527 chr5:142782415 NR3C1 0.42 5.87 0.3 1.02e-8 Night sleep phenotypes; LIHC cis rs6582630 0.502 rs11522899 chr12:38270637 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Drug-induced liver injury (flucloxacillin); LIHC cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg05025164 chr4:1340916 KIAA1530 0.67 10.49 0.49 1.65e-22 Longevity; LIHC cis rs7107356 1 rs7107356 chr11:47676170 A/G cg20307385 chr11:47447363 PSMC3 0.81 12.74 0.57 1.0500000000000001e-30 Neuroticism;Neuroticism (multi-trait analysis); LIHC cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg12016809 chr21:47604291 C21orf56 0.42 6.33 0.32 7.92e-10 Testicular germ cell tumor; LIHC trans rs8002861 0.935 rs4942256 chr13:44455920 A/T cg17145862 chr1:211918768 LPGAT1 0.67 13.17 0.58 2.64e-32 Leprosy; LIHC cis rs7534824 0.625 rs61780332 chr1:101484733 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.7 7.03 0.36 1.13e-11 Refractive astigmatism; LIHC cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg07133347 chr1:107600762 PRMT6 -0.45 -6.75 -0.34 6.45e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs78456975 1.000 rs6720874 chr2:1580504 A/G cg01028140 chr2:1542097 TPO -0.48 -5.97 -0.31 6.02e-9 Placebo response in major depressive disorder (% change in symptom score); LIHC cis rs12586317 0.620 rs79832710 chr14:35547434 G/T cg05294307 chr14:35346193 BAZ1A -0.46 -6.72 -0.34 7.6e-11 Psoriasis; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 14.7 0.62 2.84e-38 Prudent dietary pattern; LIHC cis rs7412746 0.611 rs9661876 chr1:150910911 C/T cg17724175 chr1:150552817 MCL1 0.38 7.59 0.38 3.03e-13 Melanoma; LIHC cis rs763121 0.853 rs5757234 chr22:39072686 C/T cg06022373 chr22:39101656 GTPBP1 0.75 15.33 0.64 9.55e-41 Menopause (age at onset); LIHC cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.4 0.37 1.05e-12 Prudent dietary pattern; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg06742800 chr2:27255708 TMEM214 0.44 6.55 0.33 2.09e-10 Lung function (FEV1/FVC); LIHC trans rs9914544 1.000 rs67411574 chr17:18797337 A/G cg04702396 chr17:15466718 FAM18B2 0.44 6.65 0.34 1.18e-10 Educational attainment (years of education); LIHC cis rs263063 0.764 rs2291148 chr19:5077583 A/G cg18473234 chr19:5097819 KDM4B -0.61 -7.36 -0.37 1.42e-12 Periodontitis (CDC/AAP); LIHC cis rs12477438 1.000 rs995617 chr2:99857904 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.58 6.53 0.33 2.35e-10 Chronic sinus infection; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg01964233 chr2:99757837 C2orf15;TSGA10 -0.5 -6.06 -0.31 3.55e-9 Systolic blood pressure; LIHC cis rs1387259 0.899 rs7307566 chr12:48604682 A/G cg21466736 chr12:48725269 NA -0.7 -10.55 -0.5 1.06e-22 Obstructive sleep apnea trait (apnea hypopnea index); LIHC cis rs6089584 0.893 rs6089305 chr20:60571817 T/C cg23262073 chr20:60523788 NA -0.29 -6.06 -0.31 3.68e-9 Body mass index; LIHC cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg12310025 chr6:25882481 NA 0.9 12.22 0.55 9.87e-29 Blood metabolite levels; LIHC cis rs11577318 0.853 rs12728971 chr1:26626612 C/T cg18121669 chr1:26560928 CCDC21 0.5 8.0 0.4 1.91e-14 Granulocyte percentage of myeloid white cells; LIHC cis rs2479724 0.901 rs2185798 chr6:41773576 G/C cg17623882 chr6:41773611 USP49 0.56 8.78 0.43 8.17e-17 Menarche (age at onset); LIHC cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.69 0.43 1.53e-16 Platelet count; LIHC cis rs742614 0.533 rs6059497 chr20:32446960 C/G cg06304546 chr20:32448765 NA -0.41 -5.81 -0.3 1.4e-8 Stearic acid (18:0) levels; LIHC cis rs950169 0.922 rs11633534 chr15:85124642 C/T cg03959625 chr15:84868606 LOC388152 0.45 6.1 0.31 2.93e-9 Schizophrenia; LIHC trans rs1814175 0.727 rs2140597 chr11:49873946 G/A cg15704280 chr7:45808275 SEPT13 -1.01 -23.61 -0.79 8.2e-74 Height; LIHC cis rs9733 0.650 rs9803935 chr1:150552622 T/G cg18016565 chr1:150552671 MCL1 -0.55 -11.08 -0.51 1.37e-24 Tonsillectomy; LIHC cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg03517284 chr6:25882590 NA -0.6 -8.51 -0.42 5.64e-16 Blood metabolite levels; LIHC cis rs3862030 0.720 rs11593583 chr10:104228149 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.51 7.64 0.38 2.14e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs1865760 0.534 rs72834629 chr6:26023032 C/T cg16482183 chr6:26056742 HIST1H1C 0.44 6.12 0.31 2.53e-9 Height; LIHC trans rs6600671 1.000 rs1832558 chr1:121177380 A/G cg09829573 chr1:144692074 NBPF9 -0.43 -7.95 -0.39 2.76e-14 Hip geometry; LIHC cis rs9393777 0.623 rs9348719 chr6:26470032 T/C cg12826209 chr6:26865740 GUSBL1 0.66 6.93 0.35 2.07e-11 Intelligence (multi-trait analysis); LIHC trans rs9929218 1.000 rs2113199 chr16:68814502 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 -0.59 -8.67 -0.42 1.71e-16 Colorectal cancer; LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg06873352 chr17:61820015 STRADA 0.73 12.99 0.57 1.21e-31 Prudent dietary pattern; LIHC cis rs6502050 0.871 rs9916649 chr17:80075739 G/A cg11859384 chr17:80120422 CCDC57 0.43 5.9 0.3 8.52e-9 Life satisfaction; LIHC cis rs593982 0.920 rs10896044 chr11:65554680 C/G cg08755490 chr11:65554678 OVOL1 0.55 8.23 0.41 3.87e-15 Atopic dermatitis; LIHC cis rs2760061 0.819 rs1745417 chr1:228204279 C/T cg02753203 chr1:228287806 NA 0.5 8.28 0.41 2.87e-15 Diastolic blood pressure; LIHC cis rs9818758 0.607 rs5030795 chr3:49141116 C/T cg00383909 chr3:49044727 WDR6 0.83 7.56 0.38 3.76e-13 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs2439831 0.867 rs2412779 chr15:43655927 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.93 17.36 0.68 7.38e-49 Lung cancer in ever smokers; LIHC cis rs11098499 0.754 rs12510269 chr4:120241646 A/G cg09307838 chr4:120376055 NA 0.71 11.16 0.52 7.05e-25 Corneal astigmatism; LIHC cis rs2839627 0.561 rs9977774 chr21:44342476 G/C cg03543861 chr21:44258195 NA 0.52 7.45 0.37 7.6e-13 Information processing speed; LIHC trans rs12478296 0.901 rs6731775 chr2:242999443 T/C cg01596870 chr19:55963115 NA -0.67 -9.59 -0.46 1.96e-19 Obesity-related traits; LIHC cis rs12477438 0.765 rs72957180 chr2:99694452 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -1.11 -16.01 -0.65 1.99e-43 Chronic sinus infection; LIHC cis rs1005277 0.579 rs2008449 chr10:38414204 A/T cg03665457 chr10:38645376 HSD17B7P2 0.39 5.77 0.3 1.81e-8 Extrinsic epigenetic age acceleration; LIHC cis rs1008375 0.866 rs12233712 chr4:17570063 T/A cg16339924 chr4:17578868 LAP3 0.43 5.79 0.3 1.58e-8 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs8005677 1.000 rs1043209 chr14:23373986 A/G cg25600027 chr14:23388339 RBM23 0.42 6.18 0.32 1.83e-9 Cognitive ability (multi-trait analysis); LIHC cis rs9733 0.596 rs11204687 chr1:150629880 C/A cg13175981 chr1:150552382 MCL1 -0.43 -6.03 -0.31 4.3e-9 Tonsillectomy; LIHC cis rs1538970 0.884 rs1771551 chr1:45883643 C/G cg15605315 chr1:45957053 TESK2 -0.43 -5.88 -0.3 9.66e-9 Platelet count; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg05484376 chr2:27715224 FNDC4 0.37 6.34 0.32 7.32e-10 Total body bone mineral density; LIHC cis rs12477438 0.677 rs12475034 chr2:99699464 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.03 -12.2 -0.55 1.11e-28 Chronic sinus infection; LIHC cis rs9303401 0.734 rs8073316 chr17:57211381 A/T cg12560992 chr17:57184187 TRIM37 -0.56 -7.74 -0.39 1.1e-13 Cognitive test performance; LIHC cis rs66725070 1 rs66725070 chr15:58267416 GACAT/G cg12031962 chr15:58353849 ALDH1A2 -0.32 -6.33 -0.32 7.73e-10 Barrett's esophagus; LIHC cis rs3857067 0.773 rs2865344 chr4:95103040 C/T cg11021082 chr4:95130006 SMARCAD1 -0.42 -7.43 -0.37 8.48e-13 QT interval; LIHC cis rs4638749 0.734 rs35184015 chr2:108870540 C/T cg25838818 chr2:108905173 SULT1C2 -0.39 -6.93 -0.35 2.11e-11 Blood pressure; LIHC cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg06558623 chr16:89946397 TCF25 0.87 13.67 0.59 2.97e-34 Skin colour saturation; LIHC cis rs694739 0.628 rs11606081 chr11:64137875 T/C cg23796481 chr11:64053134 BAD;GPR137 0.46 6.22 0.32 1.42e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs1395 0.744 rs11126934 chr2:27476613 T/C cg22903471 chr2:27725779 GCKR -0.4 -6.0 -0.31 4.95e-9 Blood metabolite levels; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg13404532 chr3:128483276 RAB7A -0.39 -6.06 -0.31 3.59e-9 Calcium levels; LIHC cis rs600806 0.713 rs10745305 chr1:110012148 A/G cg10127483 chr1:110009974 SYPL2 0.5 6.4 0.33 5.26e-10 Intelligence (multi-trait analysis); LIHC cis rs2073300 1.000 rs6106655 chr20:23441982 C/G cg16736954 chr20:23401023 NAPB 0.52 5.78 0.3 1.71e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs919433 0.680 rs2124317 chr2:198477606 G/A cg03934865 chr2:198174659 NA 0.51 7.72 0.39 1.3e-13 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs17818399 0.620 rs7598578 chr2:46857085 T/C cg02822958 chr2:46747628 ATP6V1E2 0.37 5.87 0.3 1.01e-8 Height; LIHC cis rs12765878 1.000 rs2067832 chr10:105643134 G/A cg11005552 chr10:105648138 OBFC1 0.39 6.15 0.32 2.2e-9 Coronary artery disease; LIHC cis rs801193 1.000 rs17566701 chr7:66193183 T/C cg11764359 chr7:65958608 NA 0.68 10.0 0.48 7.83e-21 Aortic root size; LIHC cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg13770153 chr20:60521292 NA -0.36 -7.16 -0.36 5e-12 Body mass index; LIHC cis rs10197940 0.624 rs17270233 chr2:152372420 A/G cg06191203 chr2:152266755 RIF1 -0.44 -7.46 -0.37 7.07e-13 Lung cancer; LIHC cis rs10791097 0.694 rs4937581 chr11:130740335 T/C cg14779329 chr11:130786720 SNX19 0.4 6.03 0.31 4.25e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs17253792 0.822 rs76612185 chr14:56037706 T/C cg01858014 chr14:56050164 KTN1 -0.72 -7.0 -0.35 1.36e-11 Putamen volume; LIHC cis rs6942756 1.000 rs7803052 chr7:128959427 A/G cg02491457 chr7:128862824 NA -0.63 -9.1 -0.44 7.75e-18 White matter hyperintensity burden; LIHC cis rs763121 0.819 rs3747173 chr22:39069045 A/G cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs10791097 0.694 rs3190331 chr11:130748131 C/T cg22079354 chr11:130786696 SNX19 -0.41 -5.91 -0.3 8.4e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg10295955 chr4:187884368 NA -0.97 -22.08 -0.77 8.55e-68 Lobe attachment (rater-scored or self-reported); LIHC cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg11494091 chr17:61959527 GH2 0.36 6.12 0.31 2.63e-9 Height; LIHC cis rs2842992 0.789 rs6908680 chr6:160218209 G/T cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.7 0.57 1.48e-30 Age-related macular degeneration (geographic atrophy); LIHC trans rs10230207 0.963 rs4236296 chr7:19616437 T/G cg04830814 chr5:32174484 GOLPH3 -0.41 -6.11 -0.31 2.77e-9 Intracranial aneurysm; LIHC cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg21724239 chr8:58056113 NA 0.57 7.46 0.37 7.23e-13 Developmental language disorder (linguistic errors); LIHC cis rs924607 1.000 rs12523022 chr5:598643 C/T cg04221910 chr5:616842 CEP72 -0.41 -7.11 -0.36 6.61e-12 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; LIHC cis rs11671005 0.779 rs3752112 chr19:58992220 T/G cg25952890 chr19:58913133 NA 0.71 7.31 0.37 1.9e-12 Mean platelet volume; LIHC cis rs6542838 0.704 rs56125264 chr2:99516699 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.41 -5.89 -0.3 9.08e-9 Fear of minor pain; LIHC cis rs11229555 0.645 rs10896774 chr11:58175837 T/G cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.58e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs6942756 0.876 rs822038 chr7:129065477 A/G cg02491457 chr7:128862824 NA -0.6 -9.33 -0.45 1.39e-18 White matter hyperintensity burden; LIHC cis rs72843506 0.722 rs9908418 chr17:20214565 A/G cg12065943 chr17:19881925 AKAP10 -0.33 -5.87 -0.3 1.05e-8 Schizophrenia; LIHC cis rs7715806 0.500 rs17563700 chr5:74986045 A/G cg00601450 chr5:74908170 NA 0.59 7.12 0.36 6.53e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6062302 0.522 rs3761126 chr20:62252044 C/T cg16989086 chr20:62203971 PRIC285 0.56 8.05 0.4 1.41e-14 Glioblastoma; LIHC cis rs1048238 0.506 rs848209 chr1:16256007 T/C cg00529422 chr1:16285251 ZBTB17 0.35 6.54 0.33 2.24e-10 Systolic blood pressure; LIHC trans rs11165623 0.564 rs7541109 chr1:96995960 C/A cg10631902 chr5:14652156 NA -0.3 -6.84 -0.35 3.59e-11 Hip circumference;Waist circumference; LIHC cis rs832187 0.640 rs704367 chr3:63868777 A/C cg16258503 chr3:63850278 ATXN7;THOC7 0.42 5.8 0.3 1.52e-8 Schizophrenia; LIHC cis rs9733 0.536 rs6661415 chr1:150635869 G/A cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs8044995 0.706 rs73612697 chr16:68162016 G/A cg09835421 chr16:68378352 PRMT7 -0.55 -6.26 -0.32 1.16e-9 Schizophrenia; LIHC cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg23172400 chr8:95962367 TP53INP1 -0.36 -8.01 -0.4 1.88e-14 Type 2 diabetes; LIHC cis rs9902453 0.967 rs1042173 chr17:28525011 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.09 0.44 8.02e-18 Coffee consumption (cups per day); LIHC cis rs9807989 0.524 rs6543126 chr2:103027104 G/A cg03938978 chr2:103052716 IL18RAP 0.3 5.72 0.3 2.34e-8 Asthma; LIHC cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg18404041 chr3:52824283 ITIH1 -0.55 -8.87 -0.43 4.05e-17 Bipolar disorder; LIHC cis rs7552404 1.000 rs7552404 chr1:76135946 A/G cg22875332 chr1:76189707 ACADM 0.49 7.3 0.37 1.98e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9549367 0.789 rs9549361 chr13:113898329 C/T cg18105134 chr13:113819100 PROZ 0.66 11.41 0.52 9.23e-26 Platelet distribution width; LIHC cis rs2663905 0.664 rs2460855 chr15:81361729 G/T cg09888468 chr15:81410853 NA -0.38 -6.36 -0.33 6.36e-10 QT interval (drug interaction); LIHC cis rs735396 0.770 rs2464196 chr12:121435427 G/A cg25281562 chr12:121454272 C12orf43 0.36 6.27 0.32 1.06e-9 N-glycan levels; LIHC cis rs96067 0.772 rs1033891 chr1:36608402 A/G cg24686825 chr1:36642396 MAP7D1 -0.35 -5.89 -0.3 9.28e-9 Corneal structure; LIHC cis rs769267 0.895 rs2965182 chr19:19548246 A/G cg26732615 chr19:19648335 CILP2;YJEFN3 0.39 5.88 0.3 9.86e-9 Tonsillectomy; LIHC cis rs71386921 1 rs71386921 chr10:27478698 AAT/A cg14442939 chr10:27389572 ANKRD26 0.7 8.29 0.41 2.54e-15 Breast cancer; LIHC cis rs7731783 1 rs7731783 chr5:177060312 T/C cg03143697 chr5:177099378 LOC202181 -0.39 -6.33 -0.32 7.53e-10 Methadone dose in opioid dependence; LIHC cis rs4332037 0.901 rs11767040 chr7:1945468 C/T cg23422044 chr7:1970798 MAD1L1 -0.64 -7.31 -0.37 1.88e-12 Bipolar disorder; LIHC cis rs2933343 0.729 rs789228 chr3:128601050 A/G cg25356066 chr3:128598488 ACAD9 0.55 7.69 0.38 1.6e-13 IgG glycosylation; LIHC cis rs1198430 0.925 rs2811975 chr1:23801081 A/T cg19827787 chr1:23763612 ASAP3 0.36 6.3 0.32 8.94e-10 Total cholesterol levels; LIHC trans rs2727020 0.894 rs10839265 chr11:49369733 C/T cg15704280 chr7:45808275 SEPT13 -0.74 -11.25 -0.52 3.48e-25 Coronary artery disease; LIHC cis rs600806 0.627 rs2359652 chr1:110008720 T/A cg11161837 chr1:110010384 SYPL2 0.46 6.3 0.32 9.14e-10 Intelligence (multi-trait analysis); LIHC cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs3820068 0.677 rs72643691 chr1:15856251 T/C cg17385448 chr1:15911702 AGMAT 0.37 6.45 0.33 3.93e-10 Systolic blood pressure; LIHC cis rs1023500 0.505 rs134886 chr22:42673856 C/T cg04733989 chr22:42467013 NAGA -0.42 -6.38 -0.33 5.73e-10 Schizophrenia; LIHC cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg05665937 chr4:1216051 CTBP1 0.45 6.26 0.32 1.17e-9 Obesity-related traits; LIHC cis rs17125944 0.505 rs10483617 chr14:53202605 A/G cg13660082 chr14:53194042 PSMC6 0.49 7.82 0.39 6.71e-14 Alzheimer's disease (late onset); LIHC cis rs60871478 0.947 rs4074610 chr7:791755 G/A cg04727924 chr7:799746 HEATR2 -0.57 -8.5 -0.42 5.81e-16 Cerebrospinal P-tau181p levels; LIHC cis rs7582180 0.614 rs1530030 chr2:101009600 G/A cg14675211 chr2:100938903 LONRF2 0.54 8.31 0.41 2.21e-15 Intelligence (multi-trait analysis); LIHC cis rs769267 0.965 rs735273 chr19:19385411 T/C cg03709012 chr19:19516395 GATAD2A 0.94 15.49 0.64 2.25e-41 Tonsillectomy; LIHC cis rs4727027 0.865 rs62505077 chr7:148849656 T/A cg23583168 chr7:148888333 NA -0.74 -10.5 -0.49 1.51e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs3096299 0.606 rs2965946 chr16:89516612 T/C cg06640241 chr16:89574553 SPG7 0.6 8.41 0.41 1.11e-15 Multiple myeloma (IgH translocation); LIHC cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs3806843 0.966 rs1030163 chr5:140185132 G/A cg19875535 chr5:140030758 IK 0.36 5.81 0.3 1.41e-8 Depressive symptoms (multi-trait analysis); LIHC trans rs877282 0.898 rs35743076 chr10:758991 C/T cg22713356 chr15:30763199 NA 1.39 12.18 0.55 1.41e-28 Uric acid levels; LIHC cis rs965469 0.779 rs6037568 chr20:3333245 C/T cg25506879 chr20:3388711 C20orf194 -0.53 -6.54 -0.33 2.22e-10 IFN-related cytopenia; LIHC cis rs8044995 0.563 rs56331745 chr16:68368770 G/T cg09835421 chr16:68378352 PRMT7 -0.87 -10.08 -0.48 4.15e-21 Schizophrenia; LIHC cis rs1401999 0.966 rs2313216 chr3:183637251 C/T cg01324343 chr3:183735012 ABCC5 0.64 10.67 0.5 3.82e-23 Anterior chamber depth; LIHC cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs10503871 1.000 rs10503872 chr8:30437031 C/G cg26383811 chr8:30366931 RBPMS -0.44 -7.56 -0.38 3.77e-13 Metabolite levels (X-11787); LIHC cis rs782590 0.967 rs2627759 chr2:55853341 T/C cg18811423 chr2:55921094 PNPT1 0.99 15.95 0.65 3.2e-43 Metabolic syndrome; LIHC trans rs4718428 0.672 rs4718412 chr7:66286867 C/T cg10756647 chr7:56101905 PSPH -0.61 -8.27 -0.41 2.94e-15 Corneal structure; LIHC cis rs910316 0.934 rs4903278 chr14:75535019 C/A cg08847533 chr14:75593920 NEK9 0.89 19.77 0.73 1.49e-58 Height; LIHC cis rs41271473 0.526 rs942852 chr1:228730748 A/G cg10167378 chr1:228756711 NA 0.66 6.76 0.34 6.02e-11 Chronic lymphocytic leukemia; LIHC cis rs9902453 0.765 rs2617883 chr17:28120488 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -13.71 -0.6 2.11e-34 Coffee consumption (cups per day); LIHC cis rs6547741 1.000 rs6547734 chr2:27830990 G/T cg27432699 chr2:27873401 GPN1 0.72 11.65 0.53 1.26e-26 Oral cavity cancer; LIHC trans rs6984305 0.541 rs17716118 chr8:9180134 A/G cg08911368 chr8:11471085 NA 0.43 6.37 0.33 6.25e-10 Liver enzyme levels (alkaline phosphatase); LIHC cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg21724239 chr8:58056113 NA -0.57 -7.39 -0.37 1.14e-12 Developmental language disorder (linguistic errors); LIHC trans rs7677751 0.806 rs6850748 chr4:55099164 T/G cg17183009 chr3:120277827 NA 0.52 6.08 0.31 3.18e-9 Corneal astigmatism; LIHC cis rs9918079 0.560 rs4270584 chr4:15600799 A/G cg21329975 chr4:15471214 CC2D2A 0.45 6.8 0.35 4.62e-11 Obesity-related traits; LIHC cis rs10508774 0.925 rs12268816 chr10:32924542 C/T cg01819863 chr10:32635814 EPC1 0.64 5.89 0.3 9.43e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7945718 0.621 rs10831891 chr11:12676140 A/G cg25843174 chr11:12811716 TEAD1 0.33 7.71 0.38 1.42e-13 Educational attainment (years of education); LIHC cis rs908922 0.676 rs10888492 chr1:152499908 G/C cg20991723 chr1:152506922 NA 0.57 10.12 0.48 3.18e-21 Hair morphology; LIHC cis rs8067354 0.645 rs2645487 chr17:57886125 T/G cg13753209 chr17:57696993 CLTC 0.74 11.66 0.53 1.11e-26 Hemoglobin concentration; LIHC cis rs2573652 1.000 rs7163481 chr15:100516916 C/G cg09918751 chr15:100517450 ADAMTS17 0.82 15.43 0.64 3.9e-41 Height; LIHC trans rs7227401 1.000 rs7227401 chr18:21938658 G/T cg09797837 chr1:17734771 RCC2 0.68 6.26 0.32 1.12e-9 Osteoporosis-related phenotypes; LIHC cis rs9911578 0.967 rs4076229 chr17:56937256 C/T cg05425664 chr17:57184151 TRIM37 -0.6 -8.91 -0.43 3.1e-17 Intelligence (multi-trait analysis); LIHC cis rs8049603 0.524 rs35476232 chr16:23092821 T/C cg16484020 chr16:23217411 SCNN1G -0.23 -5.77 -0.3 1.82e-8 Multiple sclerosis; LIHC cis rs9486715 0.867 rs4598081 chr6:96975227 A/G cg18709589 chr6:96969512 KIAA0776 0.33 5.86 0.3 1.08e-8 Headache; LIHC cis rs858239 0.537 rs10279691 chr7:23228387 A/G cg18081818 chr7:23246105 NA -0.4 -5.8 -0.3 1.55e-8 Cerebrospinal fluid biomarker levels; LIHC cis rs240764 0.658 rs7747014 chr6:101201898 T/G cg09795085 chr6:101329169 ASCC3 -0.56 -8.06 -0.4 1.34e-14 Neuroticism; LIHC cis rs6545883 0.929 rs1186707 chr2:61673520 C/A cg14146966 chr2:61757674 XPO1 0.47 8.19 0.4 5.25e-15 Tuberculosis; LIHC cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg02034447 chr16:89574710 SPG7 0.51 7.76 0.39 1.01e-13 Multiple myeloma (IgH translocation); LIHC cis rs6762 0.748 rs28677123 chr11:840604 C/G cg07691484 chr11:842764 TSPAN4;POLR2L -0.75 -9.51 -0.46 3.39e-19 Mean platelet volume; LIHC cis rs7927592 0.913 rs7115374 chr11:68300076 G/T cg01657329 chr11:68192670 LRP5 -0.47 -6.08 -0.31 3.22e-9 Total body bone mineral density; LIHC cis rs1055129 0.560 rs3682 chr17:73942150 A/G cg08125733 chr17:73851984 WBP2 0.56 8.64 0.42 2.26e-16 White matter hyperintensity burden; LIHC cis rs12188164 0.525 rs2561665 chr5:460135 A/G cg16584290 chr5:462447 EXOC3 0.37 5.99 0.31 5.28e-9 Cystic fibrosis severity; LIHC cis rs8044868 1.000 rs8044868 chr16:72162102 C/T cg16558253 chr16:72132732 DHX38 -0.39 -6.35 -0.32 6.94e-10 Body mass index (change over time) in cancer or chronic obstructive pulmonary disease;Body mass index (change over time) in cancer; LIHC cis rs6582630 0.555 rs11182202 chr12:38476451 C/G cg13010199 chr12:38710504 ALG10B 0.46 6.14 0.31 2.35e-9 Drug-induced liver injury (flucloxacillin); LIHC cis rs2842992 0.915 rs2758350 chr6:160118056 A/G cg11366901 chr6:160182831 ACAT2 0.92 14.81 0.63 1.1e-38 Age-related macular degeneration (geographic atrophy); LIHC cis rs7487075 0.567 rs7486580 chr12:46828348 C/A cg23829395 chr12:46796953 NA 0.35 6.12 0.31 2.62e-9 Itch intensity from mosquito bite; LIHC trans rs1005277 0.602 rs1780141 chr10:38504299 T/C cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs2749592 0.588 rs2505192 chr10:38395023 G/A cg25427524 chr10:38739819 LOC399744 -0.64 -11.51 -0.53 3.92e-26 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs875971 0.502 rs6460311 chr7:66111873 C/T cg11764359 chr7:65958608 NA -0.59 -8.14 -0.4 7.65e-15 Aortic root size; LIHC cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg08067268 chr2:26466485 HADHB;HADHA -0.44 -6.54 -0.33 2.23e-10 Gut microbiome composition (summer); LIHC cis rs5758511 0.689 rs5758691 chr22:42668504 G/C cg00645731 chr22:42541494 CYP2D7P1 0.51 8.2 0.41 4.75e-15 Birth weight; LIHC cis rs12477438 0.501 rs2632284 chr2:99775865 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.38 0.61 5.11e-37 Chronic sinus infection; LIHC cis rs1570884 0.516 rs7334387 chr13:50172133 T/A cg03651054 chr13:50194643 NA 0.37 6.62 0.34 1.42e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; LIHC cis rs8062405 0.964 rs7193733 chr16:28875482 A/G cg16576597 chr16:28551801 NUPR1 0.38 6.24 0.32 1.32e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs6430585 0.528 rs12464050 chr2:136663110 G/T cg07169764 chr2:136633963 MCM6 1.29 21.37 0.76 5.86e-65 Corneal structure; LIHC cis rs9322193 0.607 rs9322229 chr6:150230085 A/G cg01145232 chr6:150245071 RAET1G 0.37 7.36 0.37 1.34e-12 Lung cancer; LIHC cis rs7647973 0.588 rs9883000 chr3:49667691 A/G cg03060546 chr3:49711283 APEH 0.54 6.42 0.33 4.44e-10 Menarche (age at onset); LIHC cis rs34779708 0.733 rs7083266 chr10:35541632 C/A cg03585969 chr10:35415529 CREM 0.76 10.96 0.51 3.65e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4478037 0.822 rs9875140 chr3:33117068 T/A cg16652328 chr3:33138982 GLB1;TMPPE -0.54 -7.01 -0.35 1.32e-11 Major depressive disorder; LIHC cis rs10426930 0.607 rs2613762 chr19:5064948 T/G cg18473234 chr19:5097819 KDM4B -0.59 -7.09 -0.36 7.84e-12 Monocyte percentage of white cells; LIHC cis rs5769707 0.521 rs7285764 chr22:50058561 T/C cg01652190 chr22:50026171 C22orf34 -0.29 -6.34 -0.32 7.24e-10 Monocyte count;Monocyte percentage of white cells; LIHC trans rs7677751 0.806 rs1800812 chr4:55094629 G/T cg17183009 chr3:120277827 NA 0.52 6.09 0.31 3.02e-9 Corneal astigmatism; LIHC cis rs9790314 0.905 rs7632797 chr3:161002694 C/T cg03342759 chr3:160939853 NMD3 0.73 9.63 0.46 1.42e-19 Morning vs. evening chronotype; LIHC cis rs2439831 0.850 rs12101756 chr15:44053887 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.43 0.33 4.32e-10 Lung cancer in ever smokers; LIHC cis rs1538970 1.000 rs2050884 chr1:45830824 A/G cg05343316 chr1:45956843 TESK2 0.54 8.12 0.4 8.47e-15 Platelet count; LIHC cis rs2404602 0.716 rs17364076 chr15:76760891 C/T cg23625390 chr15:77176239 SCAPER 0.38 6.2 0.32 1.6e-9 Blood metabolite levels; LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg15695585 chr7:114562711 MDFIC 0.44 6.04 0.31 4.05e-9 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs6754311 0.773 rs4988183 chr2:136622046 T/C cg07169764 chr2:136633963 MCM6 0.76 12.06 0.55 3.69e-28 Mosquito bite size; LIHC cis rs7208859 0.623 rs9916727 chr17:29107472 A/G cg14067834 chr17:29058358 SUZ12P 0.7 6.91 0.35 2.31e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs9733 0.791 rs11800059 chr1:150651175 C/T cg13175981 chr1:150552382 MCL1 0.52 8.12 0.4 8.36e-15 Tonsillectomy; LIHC cis rs7662987 0.517 rs1154406 chr4:100008494 T/C cg12011299 chr4:100065546 ADH4 0.65 10.71 0.5 2.86e-23 Smoking initiation; LIHC cis rs875971 0.862 rs4236208 chr7:65749078 C/T cg18252515 chr7:66147081 NA 0.44 6.3 0.32 9.27e-10 Aortic root size; LIHC trans rs2243480 1.000 rs56291018 chr7:65390339 G/A cg10756647 chr7:56101905 PSPH 1.1 13.42 0.59 2.8e-33 Diabetic kidney disease; LIHC cis rs4891159 0.790 rs11150953 chr18:74145491 G/A cg24786174 chr18:74118243 ZNF516 -0.73 -13.02 -0.58 9.31e-32 Longevity; LIHC cis rs35306767 0.903 rs35968821 chr10:910225 A/G cg26597838 chr10:835615 NA 1.18 14.34 0.61 7.88e-37 Eosinophil percentage of granulocytes; LIHC cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs589448 0.902 rs2603090 chr12:69777188 G/A cg22834771 chr12:69754056 YEATS4 -0.54 -9.87 -0.47 2.23e-20 Cerebrospinal fluid biomarker levels; LIHC cis rs6024905 0.587 rs1579101 chr20:36966334 C/T cg07053727 chr20:36965646 BPI 0.59 10.91 0.51 5.48e-24 Bipolar disorder and schizophrenia; LIHC cis rs4650994 0.593 rs6694406 chr1:178532010 C/T cg05350800 chr1:178550844 NA -0.34 -7.47 -0.37 6.81e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs79839061 0.610 rs1564282 chr4:852313 C/T cg07828340 chr4:882639 GAK 0.83 7.07 0.36 8.83e-12 Intelligence (multi-trait analysis); LIHC cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg22029157 chr1:209979665 IRF6 0.48 7.61 0.38 2.64e-13 Cleft lip with or without cleft palate; LIHC cis rs3020736 0.500 rs6002623 chr22:42513761 G/A cg00645731 chr22:42541494 CYP2D7P1 -0.39 -6.2 -0.32 1.67e-9 Autism spectrum disorder or schizophrenia; LIHC cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg06238570 chr21:40685208 BRWD1 0.6 7.11 0.36 6.92e-12 Cognitive function; LIHC cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg24879335 chr3:133465180 TF 0.28 6.11 0.31 2.69e-9 Iron status biomarkers; LIHC trans rs6445975 1.000 rs4076852 chr3:58375286 C/T cg16351352 chr14:55738545 FBXO34 0.47 6.26 0.32 1.12e-9 Systemic lupus erythematosus; LIHC cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg09417038 chr21:47716443 C21orf57 0.67 10.11 0.48 3.49e-21 Testicular germ cell tumor; LIHC cis rs11628318 0.591 rs8010679 chr14:103155637 T/G cg23461800 chr14:103021989 NA 0.39 5.82 0.3 1.36e-8 Platelet count; LIHC cis rs17106184 1.000 rs57839936 chr1:51306273 T/C cg07174182 chr1:51127561 FAF1 -0.62 -6.54 -0.33 2.27e-10 Type 2 diabetes; LIHC cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg08677398 chr8:58056175 NA 0.39 6.06 0.31 3.68e-9 Developmental language disorder (linguistic errors); LIHC cis rs4660306 0.677 rs1691217 chr1:45900190 T/C cg03123370 chr1:45965343 CCDC163P;MMACHC 0.66 6.7 0.34 8.39e-11 Homocysteine levels; LIHC cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg14004847 chr7:1930337 MAD1L1 -0.47 -6.9 -0.35 2.49e-11 Bipolar disorder and schizophrenia; LIHC cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs2760061 0.599 rs644794 chr1:228148670 T/C cg02753203 chr1:228287806 NA -0.49 -7.79 -0.39 8.04e-14 Diastolic blood pressure; LIHC cis rs589448 0.535 rs12423794 chr12:69713018 G/A cg14784868 chr12:69753453 YEATS4 0.91 17.96 0.7 2.85e-51 Cerebrospinal fluid biomarker levels; LIHC cis rs2522056 1.000 rs886286 chr5:131795597 A/G cg24060327 chr5:131705240 SLC22A5 0.53 7.16 0.36 4.87e-12 Lymphocyte counts;Fibrinogen; LIHC cis rs6860806 0.507 rs273901 chr5:131694360 G/T cg24060327 chr5:131705240 SLC22A5 -0.78 -12.28 -0.55 5.8e-29 Breast cancer; LIHC cis rs3741404 0.609 rs641430 chr11:63869531 C/T cg18225595 chr11:63971243 STIP1 -0.44 -7.09 -0.36 7.76e-12 Platelet count; LIHC cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg21782813 chr7:2030301 MAD1L1 0.42 7.15 0.36 5.24e-12 Bipolar disorder and schizophrenia; LIHC cis rs3782089 1.000 rs3782089 chr11:65336819 C/T cg00206168 chr11:65308501 LTBP3 0.99 7.08 0.36 8.07e-12 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26738040 chr11:62433033 C11orf48;SNORA57;METTL12 0.41 6.26 0.32 1.18e-9 Lung function (FEV1/FVC); LIHC cis rs11025559 0.812 rs10833338 chr11:20514709 A/G cg19653624 chr11:20408972 PRMT3 -0.47 -6.22 -0.32 1.43e-9 Pursuit maintenance gain; LIHC cis rs2239547 0.657 rs7620706 chr3:52891756 A/T cg11645453 chr3:52864694 ITIH4 0.36 9.21 0.45 3.38e-18 Schizophrenia; LIHC trans rs6598955 0.616 rs11247890 chr1:26590182 G/A cg07461501 chr17:79650226 HGS;ARL16 -0.77 -8.59 -0.42 3.07e-16 Obesity-related traits; LIHC cis rs875971 0.545 rs73376394 chr7:65637681 C/T cg11764359 chr7:65958608 NA 0.48 6.6 0.34 1.57e-10 Aortic root size; LIHC cis rs3749237 0.595 rs1050088 chr3:49570882 C/T cg06212747 chr3:49208901 KLHDC8B -0.44 -5.78 -0.3 1.71e-8 Resting heart rate; LIHC cis rs11627756 0.958 rs2146429 chr14:103071816 A/T cg12046867 chr14:103022105 NA -0.4 -6.17 -0.32 1.89e-9 Mean platelet volume; LIHC cis rs11955398 0.625 rs6449485 chr5:59995441 C/T cg02684056 chr5:59996105 DEPDC1B 0.43 6.13 0.31 2.47e-9 Intelligence (multi-trait analysis); LIHC cis rs769267 0.965 rs2074296 chr19:19373689 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.45 6.21 0.32 1.56e-9 Tonsillectomy; LIHC cis rs8078723 0.714 rs2241245 chr17:38151014 C/T cg17467752 chr17:38218738 THRA -0.59 -10.14 -0.48 2.72e-21 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs311392 1.000 rs454064 chr8:55088336 C/T cg11783602 chr8:55087084 NA -0.34 -6.6 -0.34 1.53e-10 Pelvic organ prolapse (moderate/severe); LIHC cis rs9393777 0.623 rs2093169 chr6:26495099 C/T cg12826209 chr6:26865740 GUSBL1 0.66 6.98 0.35 1.5e-11 Intelligence (multi-trait analysis); LIHC cis rs7615952 0.641 rs4422257 chr3:125774363 A/G cg05084668 chr3:125655381 ALG1L -0.41 -6.4 -0.33 5.19e-10 Blood pressure (smoking interaction); LIHC cis rs7959452 0.868 rs10784774 chr12:69737879 C/T cg14784868 chr12:69753453 YEATS4 -0.73 -12.37 -0.56 2.77e-29 Blood protein levels; LIHC trans rs6934970 1.000 rs12209591 chr6:113013327 G/A cg09308777 chr6:169852575 NA 0.6 6.21 0.32 1.5e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6912958 0.559 rs451829 chr6:88041919 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.36 7.15 0.36 5.19e-12 Monocyte percentage of white cells; LIHC cis rs6429082 0.818 rs704722 chr1:235669988 G/A cg26050004 chr1:235667680 B3GALNT2 0.48 7.36 0.37 1.38e-12 Adiposity; LIHC cis rs10504073 0.584 rs11786103 chr8:49904077 A/G cg00325661 chr8:49890786 NA 0.39 9.35 0.45 1.16e-18 Blood metabolite ratios; LIHC cis rs4129767 0.647 rs1976703 chr17:76401328 C/T cg05887092 chr17:76393375 PGS1 0.35 6.81 0.35 4.38e-11 HDL cholesterol; LIHC cis rs2279817 0.863 rs74061958 chr1:18015918 A/G cg21791023 chr1:18019539 ARHGEF10L -0.68 -8.33 -0.41 2.01e-15 Neuroticism; LIHC cis rs477692 0.699 rs557311 chr10:131389484 A/G cg19680672 chr10:131412579 MGMT -0.4 -6.09 -0.31 3.05e-9 Response to temozolomide; LIHC cis rs10419226 0.625 rs12980154 chr19:18770119 C/T cg16673477 chr19:18812017 CRTC1 -0.32 -5.8 -0.3 1.51e-8 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); LIHC cis rs7208859 0.623 rs216434 chr17:28922335 G/C cg13385521 chr17:29058706 SUZ12P 0.69 6.62 0.34 1.36e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10540 1.000 rs35898083 chr11:484469 C/T cg03352830 chr11:487213 PTDSS2 0.68 5.86 0.3 1.08e-8 Body mass index; LIHC cis rs875971 1.000 rs4718357 chr7:65960878 A/G cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.64e-11 Aortic root size; LIHC cis rs3820068 0.603 rs1980607 chr1:15975237 A/G cg17385448 chr1:15911702 AGMAT 0.33 5.9 0.3 8.97e-9 Systolic blood pressure; LIHC cis rs477895 0.713 rs1059440 chr11:63991801 C/T cg05555928 chr11:63887634 MACROD1 -0.51 -6.75 -0.34 6.54e-11 Mean platelet volume; LIHC cis rs875971 1.000 rs6958277 chr7:65979349 A/G cg18876405 chr7:65276391 NA 0.37 6.74 0.34 6.6e-11 Aortic root size; LIHC cis rs13191362 1.000 rs35818596 chr6:163001874 C/G cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.94 0.31 6.98e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs870825 0.616 rs6552808 chr4:185642865 G/T cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC cis rs2760061 0.626 rs591582 chr1:228117360 C/A cg02753203 chr1:228287806 NA -0.5 -7.94 -0.39 2.91e-14 Diastolic blood pressure; LIHC cis rs11190604 0.767 rs7916904 chr10:102186778 C/G cg07080220 chr10:102295463 HIF1AN 0.48 7.22 0.36 3.38e-12 Palmitoleic acid (16:1n-7) levels; LIHC cis rs2637266 0.749 rs4979831 chr10:78457588 G/T cg18941641 chr10:78392320 NA 0.28 6.0 0.31 5.14e-9 Pulmonary function; LIHC cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg13395646 chr4:1353034 KIAA1530 -0.61 -8.98 -0.44 1.89e-17 Obesity-related traits; LIHC cis rs4423214 1.000 rs12790558 chr11:71170905 T/C cg24826892 chr11:71159390 DHCR7 0.48 6.16 0.32 1.99e-9 Vitamin D levels; LIHC cis rs7607369 0.580 rs7568196 chr2:219652373 G/A cg02985541 chr2:219472218 PLCD4 -0.37 -5.87 -0.3 1.04e-8 Red blood cell count;Amyotrophic lateral sclerosis; LIHC cis rs7572733 0.534 rs7572123 chr2:198769637 A/G cg00792783 chr2:198669748 PLCL1 0.46 6.81 0.35 4.47e-11 Dermatomyositis; LIHC cis rs116095464 0.558 rs6555052 chr5:224268 G/A cg22496380 chr5:211416 CCDC127 -1.02 -10.18 -0.48 1.93e-21 Breast cancer; LIHC cis rs6963495 0.818 rs73190161 chr7:105156871 C/T cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg14828511 chr1:107599125 PRMT6 0.42 6.0 0.31 5.13e-9 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6733011 0.604 rs12712035 chr2:99461298 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.42 -5.83 -0.3 1.27e-8 Bipolar disorder; LIHC cis rs7523273 0.586 rs7518047 chr1:207899332 T/C cg22525895 chr1:207977042 MIR29B2 -0.54 -8.24 -0.41 3.76e-15 Schizophrenia; LIHC cis rs10847980 0.623 rs28501453 chr12:123877312 A/G cg00376283 chr12:123451042 ABCB9 0.63 6.61 0.34 1.5e-10 Adiponectin levels; LIHC cis rs5770917 1.000 rs8137478 chr22:51017296 G/C cg10770023 chr22:51016644 CPT1B;CHKB-CPT1B -0.42 -6.12 -0.31 2.57e-9 Narcolepsy; LIHC cis rs11758351 1.000 rs16891378 chr6:26188864 A/G cg03785755 chr6:26196794 NA 0.52 6.16 0.32 2.02e-9 Gout;Renal underexcretion gout; LIHC cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg08219700 chr8:58056026 NA 0.44 5.73 0.3 2.16e-8 Developmental language disorder (linguistic errors); LIHC cis rs7296418 0.961 rs4148863 chr12:123569375 A/G cg00376283 chr12:123451042 ABCB9 0.74 13.42 0.59 2.68e-33 Platelet count; LIHC cis rs738321 0.757 rs2235345 chr22:38518177 C/T cg25457927 chr22:38595422 NA -0.32 -7.28 -0.37 2.24e-12 Breast cancer; LIHC trans rs1814175 0.645 rs10742953 chr11:49807491 C/G cg03929089 chr4:120376271 NA 0.83 15.48 0.64 2.46e-41 Height; LIHC trans rs11010290 0.639 rs17511194 chr10:36036780 A/C cg08927738 chr20:52687394 BCAS1 0.48 6.16 0.32 2.04e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; LIHC cis rs2842992 0.789 rs2342446 chr6:160220687 A/G cg19482086 chr6:160211437 TCP1;MRPL18 0.72 12.78 0.57 7.93e-31 Age-related macular degeneration (geographic atrophy); LIHC cis rs96067 0.805 rs1033890 chr1:36608414 C/T cg24686825 chr1:36642396 MAP7D1 -0.54 -7.58 -0.38 3.3e-13 Corneal structure; LIHC cis rs9549367 0.789 rs2287251 chr13:113889499 A/G cg00898013 chr13:113819073 PROZ -0.43 -7.48 -0.38 6.2800000000000005e-13 Platelet distribution width; LIHC trans rs6733379 0.588 rs2193790 chr2:34445953 A/G cg08013114 chr6:42924358 NA 0.38 6.13 0.31 2.48e-9 Attention deficit hyperactivity disorder and conduct disorder; LIHC cis rs7937682 0.632 rs11214009 chr11:111683142 T/C cg09085632 chr11:111637200 PPP2R1B 0.94 13.93 0.6 2.97e-35 Primary sclerosing cholangitis; LIHC cis rs4253772 0.591 rs6007747 chr22:46657261 A/G cg09491104 chr22:46646882 C22orf40 -0.71 -8.35 -0.41 1.68e-15 LDL cholesterol;Cholesterol, total; LIHC cis rs11758351 0.866 rs11757394 chr6:26206694 G/C cg03854865 chr6:26224070 HIST1H3E 0.63 7.23 0.36 3.28e-12 Gout;Renal underexcretion gout; LIHC cis rs7927771 1.000 rs4752856 chr11:47648042 C/T cg20307385 chr11:47447363 PSMC3 -0.45 -5.78 -0.3 1.72e-8 Subjective well-being; LIHC cis rs4803468 0.967 rs4803462 chr19:41908936 T/A cg14132834 chr19:41945861 ATP5SL -0.42 -6.25 -0.32 1.22e-9 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg18959473 chr18:159310 USP14 0.44 6.34 0.32 7.34e-10 Cognitive function; LIHC cis rs3749237 0.595 rs4855861 chr3:49525962 G/T cg02487422 chr3:49467188 NICN1 0.41 6.32 0.32 8.18e-10 Resting heart rate; LIHC cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.91 -14.04 -0.6 1.15e-35 Alzheimer's disease; LIHC cis rs60733400 0.667 rs4385650 chr1:2499898 G/A cg18854424 chr1:2615690 NA 0.33 7.1 0.36 7.34e-12 Multiple sclerosis; LIHC trans rs4774899 0.872 rs10518895 chr15:57404113 A/T cg07751341 chr19:12848092 ASNA1 -0.45 -6.15 -0.32 2.1e-9 Urinary tract infection frequency; LIHC cis rs9948 0.655 rs62156232 chr2:97431161 C/A cg01990225 chr2:97406019 LMAN2L -0.82 -6.39 -0.33 5.51e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs7520050 0.966 rs12405451 chr1:46384326 T/A cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.92e-9 Red blood cell count;Reticulocyte count; LIHC cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg03806693 chr22:41940476 POLR3H 1.12 13.03 0.58 8.92e-32 Vitiligo; LIHC cis rs10832963 1.000 rs10832956 chr11:18645668 A/G cg20219074 chr11:18656078 SPTY2D1 0.82 13.72 0.6 1.9e-34 Breast cancer; LIHC trans rs8113308 0.810 rs7258701 chr19:52445069 C/T cg14959425 chr7:20447707 ITGB8 -0.48 -6.15 -0.32 2.22e-9 Survival in endocrine treated breast cancer (estrogen-receptor positive); LIHC cis rs7584330 0.704 rs72620820 chr2:238358844 G/A cg14458575 chr2:238380390 NA 0.54 7.63 0.38 2.43e-13 Prostate cancer; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg04921814 chr1:145575587 PIAS3 -0.41 -6.44 -0.33 3.99e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs912057 0.932 rs1294406 chr6:6737737 A/G cg06612196 chr6:6737390 NA 0.55 9.98 0.48 9.13e-21 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs1395 1.000 rs6717980 chr2:27452784 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.41 -5.83 -0.3 1.27e-8 Blood metabolite levels; LIHC cis rs17685 0.753 rs869804 chr7:75688954 A/G cg04592579 chr7:75616294 TMEM120A 0.41 7.09 0.36 7.73e-12 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2576037 0.583 rs530205 chr18:44385150 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 9.76 0.47 5.08e-20 Personality dimensions; LIHC cis rs7044106 0.762 rs966397 chr9:123453312 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 7.78 0.39 8.89e-14 Hip circumference adjusted for BMI; LIHC cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.34 -0.32 7.36e-10 Colorectal cancer; LIHC cis rs17784882 0.521 rs11713693 chr3:47074906 T/C cg27129171 chr3:47204927 SETD2 -0.51 -8.14 -0.4 7.28e-15 QT interval; LIHC cis rs11098499 0.874 rs6832670 chr4:120118792 A/G cg09307838 chr4:120376055 NA 0.52 7.74 0.39 1.16e-13 Corneal astigmatism; LIHC cis rs4820539 0.966 rs2267005 chr22:23461723 A/G cg21100191 chr22:23484243 RTDR1 0.87 15.44 0.64 3.39e-41 Bone mineral density; LIHC cis rs6450176 1.000 rs6450176 chr5:53298025 G/A ch.5.1024479R chr5:53302184 ARL15 -0.82 -14.82 -0.63 9.93e-39 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2075371 0.933 rs2544191 chr7:133954248 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.8 0.39 7.68e-14 Mean platelet volume; LIHC cis rs3862030 0.668 rs12781718 chr10:104227433 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.49 -7.39 -0.37 1.11e-12 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; LIHC cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg10360139 chr7:1886902 MAD1L1 -0.41 -6.3 -0.32 9.03e-10 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg11062466 chr8:58055876 NA 0.41 5.96 0.31 6.42e-9 Developmental language disorder (linguistic errors); LIHC cis rs507080 0.922 rs558781 chr11:118564397 G/T cg04173919 chr11:118528438 PHLDB1 0.35 6.58 0.34 1.78e-10 Serum metabolite levels; LIHC cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 9.31 0.45 1.56e-18 Electroencephalogram traits; LIHC cis rs9814567 0.964 rs9815983 chr3:134222507 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.9 -0.3 8.88e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10463316 0.894 rs7727926 chr5:150767216 G/A cg03212797 chr5:150827313 SLC36A1 -0.43 -6.55 -0.33 2.07e-10 Metabolite levels (Pyroglutamine); LIHC cis rs4665809 0.878 rs4143538 chr2:26290178 A/C cg04944784 chr2:26401820 FAM59B -0.69 -8.48 -0.42 6.9e-16 Gut microbiome composition (summer); LIHC cis rs898097 0.841 rs55810435 chr17:80836722 G/C cg15369054 chr17:80825471 TBCD 0.45 6.5 0.33 2.89e-10 Breast cancer; LIHC cis rs2637266 1.000 rs7392737 chr10:78366059 C/T cg18941641 chr10:78392320 NA 0.3 6.5 0.33 2.92e-10 Pulmonary function; LIHC cis rs600806 0.778 rs10745357 chr1:110001876 G/C cg23091122 chr1:110024289 SYPL2 -0.51 -6.79 -0.34 4.91e-11 Intelligence (multi-trait analysis); LIHC cis rs6815814 0.904 rs7664239 chr4:38786304 T/C cg06935464 chr4:38784597 TLR10 0.53 9.33 0.45 1.41e-18 Breast cancer; LIHC cis rs7945705 0.967 rs56316046 chr11:8876598 G/T cg12365402 chr11:9010492 NRIP3 0.28 7.1 0.36 7.19e-12 Hemoglobin concentration; LIHC cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg11062466 chr8:58055876 NA 0.51 7.55 0.38 4.01e-13 Developmental language disorder (linguistic errors); LIHC trans rs11157436 0.918 rs11157426 chr14:22621647 A/C cg13567813 chr19:50879636 NR1H2 0.41 6.11 0.31 2.77e-9 Neurocognitive impairment in HIV-1 infection (continuous); LIHC cis rs600806 0.821 rs10127790 chr1:109891133 C/T cg02415029 chr1:110025642 ATXN7L2 -0.48 -6.33 -0.32 7.65e-10 Intelligence (multi-trait analysis); LIHC cis rs6089584 0.888 rs6061405 chr20:60617033 A/G cg23262073 chr20:60523788 NA -0.3 -6.39 -0.33 5.29e-10 Body mass index; LIHC cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.46 0.46 5.31e-19 Bipolar disorder; LIHC cis rs2380220 0.720 rs9398251 chr6:95984709 C/T cg15832292 chr6:96025679 MANEA 0.61 7.72 0.39 1.27e-13 Behavioural disinhibition (generation interaction); LIHC trans rs6600671 1.000 rs4844607 chr1:121184059 C/T cg09829573 chr1:144692074 NBPF9 0.44 7.97 0.4 2.37e-14 Hip geometry; LIHC cis rs2559856 1.000 rs2695288 chr12:102088112 T/C cg12924262 chr12:102091054 CHPT1 0.52 8.36 0.41 1.64e-15 Blood protein levels; LIHC cis rs4474465 0.850 rs11237546 chr11:78266924 T/C cg27205649 chr11:78285834 NARS2 0.44 6.73 0.34 6.96e-11 Alzheimer's disease (survival time); LIHC cis rs765787 0.530 rs10467979 chr15:45521270 G/A cg24006582 chr15:45444508 DUOX1 -0.52 -7.5 -0.38 5.55e-13 Uric acid levels; LIHC cis rs765787 0.530 rs11636395 chr15:45535684 G/C cg25801113 chr15:45476975 SHF 0.39 6.69 0.34 9.17e-11 Uric acid levels; LIHC cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg11764359 chr7:65958608 NA 0.58 6.04 0.31 4e-9 Diabetic kidney disease; LIHC cis rs4555082 1.000 rs4555082 chr14:105758964 C/T cg06808227 chr14:105710500 BRF1 -0.49 -6.49 -0.33 3.08e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs8141529 0.584 rs58004020 chr22:29257050 A/T cg15103426 chr22:29168792 CCDC117 0.67 11.35 0.52 1.52e-25 Lymphocyte counts; LIHC cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg23131131 chr22:24373011 LOC391322 -0.62 -9.22 -0.45 3.23e-18 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs10779751 0.734 rs1148485 chr1:11148759 G/A cg08854313 chr1:11322531 MTOR 0.74 9.4 0.45 8.2e-19 Body mass index; LIHC cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.86 10.93 0.51 4.64e-24 Alzheimer's disease; LIHC trans rs3942852 0.726 rs1503171 chr11:48175152 T/C cg03929089 chr4:120376271 NA -0.56 -7.62 -0.38 2.6e-13 Acute lymphoblastic leukemia (childhood); LIHC cis rs11098499 0.954 rs10008459 chr4:120394231 T/C cg09307838 chr4:120376055 NA 0.77 12.33 0.55 3.85e-29 Corneal astigmatism; LIHC cis rs6754311 0.773 rs309125 chr2:136643555 C/T cg07169764 chr2:136633963 MCM6 0.68 10.16 0.48 2.35e-21 Mosquito bite size; LIHC cis rs12594515 1.000 rs12911309 chr15:45985719 G/C cg19682013 chr15:45996608 NA 0.4 7.12 0.36 6.34e-12 Waist circumference;Weight; LIHC cis rs9828933 0.766 rs704361 chr3:63883671 T/G cg16258503 chr3:63850278 ATXN7;THOC7 0.8 10.14 0.48 2.67e-21 Type 2 diabetes; LIHC cis rs3859192 0.539 rs2305481 chr17:38138624 G/A cg17467752 chr17:38218738 THRA -0.48 -8.24 -0.41 3.77e-15 White blood cell count; LIHC cis rs738322 0.967 rs133021 chr22:38573338 T/C cg25457927 chr22:38595422 NA -0.29 -7.19 -0.36 4.17e-12 Cutaneous nevi; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg11792281 chr17:26443366 NLK 0.4 6.04 0.31 3.91e-9 Immature fraction of reticulocytes; LIHC cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg25072359 chr17:41440525 NA 0.38 6.05 0.31 3.72e-9 Menopause (age at onset); LIHC cis rs12477438 0.798 rs10167015 chr2:99570707 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.25 -0.52 3.32e-25 Chronic sinus infection; LIHC cis rs1008375 1.000 rs7673500 chr4:17621383 C/T cg16339924 chr4:17578868 LAP3 0.45 6.23 0.32 1.38e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2576037 0.523 rs590923 chr18:44404259 G/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.7 10.83 0.51 1.04e-23 Personality dimensions; LIHC cis rs611744 0.538 rs59930666 chr8:109262296 T/C cg21045802 chr8:109455806 TTC35 0.62 11.09 0.51 1.32e-24 Dupuytren's disease; LIHC cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg06238570 chr21:40685208 BRWD1 -0.57 -9.5 -0.46 3.86e-19 Cognitive function; LIHC cis rs1475911 0.708 rs56109792 chr21:43520060 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 1.08 17.23 0.68 2.56e-48 IgG glycosylation; LIHC cis rs243505 0.726 rs734005 chr7:148505864 G/A cg09806900 chr7:148480153 CUL1 0.41 6.15 0.32 2.16e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs1371867 0.846 rs2439458 chr8:101297984 T/C cg06002616 chr8:101225028 SPAG1 -0.35 -5.76 -0.3 1.83e-8 Atrioventricular conduction; LIHC cis rs7617773 0.501 rs12185901 chr3:48382919 G/T cg11946769 chr3:48343235 NME6 0.61 7.52 0.38 4.92e-13 Coronary artery disease; LIHC cis rs9611519 0.929 rs4820425 chr22:41431342 C/A cg03806693 chr22:41940476 POLR3H -0.69 -7.58 -0.38 3.37e-13 Neuroticism; LIHC cis rs7264396 0.580 rs2425181 chr20:34447709 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.57 -8.0 -0.4 1.94e-14 Total cholesterol levels; LIHC cis rs12478296 1.000 rs55717005 chr2:243041071 T/A cg18898632 chr2:242989856 NA -0.58 -7.84 -0.39 5.85e-14 Obesity-related traits; LIHC cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg24642844 chr7:1081250 C7orf50 -0.94 -9.27 -0.45 2.11e-18 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs3806843 0.735 rs778595 chr5:140036681 G/A cg19875535 chr5:140030758 IK -0.41 -6.7 -0.34 8.36e-11 Depressive symptoms (multi-trait analysis); LIHC cis rs7224685 0.530 rs7221574 chr17:4007543 T/C cg09695851 chr17:3907499 NA 0.57 6.77 0.34 5.77e-11 Type 2 diabetes; LIHC cis rs17253792 0.822 rs76557162 chr14:56064701 A/G cg01858014 chr14:56050164 KTN1 -0.78 -8.5 -0.42 6.1e-16 Putamen volume; LIHC cis rs208520 0.690 rs1318604 chr6:66825278 A/C cg07460842 chr6:66804631 NA -0.76 -8.31 -0.41 2.27e-15 Exhaled nitric oxide output; LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg01546424 chr6:149721457 MAP3K7IP2;SUMO4 0.41 6.35 0.32 6.99e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs7762018 0.505 rs79843499 chr6:170068420 A/G cg19338460 chr6:170058176 WDR27 -0.86 -9.32 -0.45 1.45e-18 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7412746 0.634 rs12096831 chr1:150864113 T/G cg18016565 chr1:150552671 MCL1 0.52 9.93 0.47 1.43e-20 Melanoma; LIHC trans rs637571 0.546 rs10791827 chr11:65596546 C/A cg17712092 chr4:129076599 LARP1B -0.68 -10.56 -0.5 9.87e-23 Eosinophil percentage of white cells; LIHC cis rs12824058 0.831 rs12322456 chr12:130813594 A/G cg26677194 chr12:130822605 PIWIL1 0.52 7.35 0.37 1.44e-12 Menopause (age at onset); LIHC cis rs35306767 0.807 rs11253513 chr10:968450 C/T cg20503657 chr10:835505 NA 0.89 10.69 0.5 3.45e-23 Eosinophil percentage of granulocytes; LIHC cis rs875971 0.862 rs35378740 chr7:65987712 C/A cg11764359 chr7:65958608 NA 0.78 13.62 0.59 4.71e-34 Aortic root size; LIHC cis rs9549367 0.804 rs9549704 chr13:113885187 T/C cg00898013 chr13:113819073 PROZ -0.42 -7.11 -0.36 6.75e-12 Platelet distribution width; LIHC cis rs17433710 0.543 rs11577330 chr1:162651672 A/T cg01063088 chr1:162760584 HSD17B7 0.45 6.27 0.32 1.11e-9 Dupuytren's disease; LIHC cis rs1816752 0.817 rs7985394 chr13:25012852 C/G cg22771759 chr13:24902376 NA 0.33 6.93 0.35 2.07e-11 Obesity-related traits; LIHC cis rs1669338 0.588 rs6784329 chr3:3200013 C/T cg16797762 chr3:3221439 CRBN -0.9 -8.14 -0.4 7.59e-15 White matter integrity; LIHC cis rs2204008 0.640 rs11520199 chr12:38211026 T/C cg26384229 chr12:38710491 ALG10B 0.86 10.74 0.5 2.28e-23 Bladder cancer; LIHC cis rs3793683 0.928 rs10781585 chr10:134553369 C/A cg27286337 chr10:134555280 INPP5A -1.03 -19.81 -0.73 1e-58 Migraine; LIHC cis rs7937682 0.924 rs12791699 chr11:111505880 T/C cg09085632 chr11:111637200 PPP2R1B -1.03 -12.34 -0.56 3.41e-29 Primary sclerosing cholangitis; LIHC cis rs992157 0.835 rs10932768 chr2:219146199 T/A cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.17 -0.55 1.48e-28 Colorectal cancer; LIHC cis rs1055129 0.537 rs10852766 chr17:73951864 T/C cg19302996 chr17:73780495 UNK 0.5 7.08 0.36 8.44e-12 White matter hyperintensity burden; LIHC cis rs3008870 0.755 rs1535365 chr1:67497613 T/C cg02640540 chr1:67518911 SLC35D1 0.44 6.89 0.35 2.76e-11 Lymphocyte percentage of white cells; LIHC cis rs72634258 0.503 rs72632055 chr1:7835774 T/G cg26816564 chr1:7831052 VAMP3 0.72 6.87 0.35 3.09e-11 Inflammatory bowel disease; LIHC trans rs7917772 0.636 rs10786708 chr10:104526245 C/T cg15420906 chr14:67688261 FAM71D 0.35 6.04 0.31 4.13e-9 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs727563 0.580 rs202626 chr22:41847190 C/A cg06481639 chr22:41940642 POLR3H 0.71 7.43 0.37 8.87e-13 Crohn's disease;Inflammatory bowel disease; LIHC cis rs10504073 0.669 rs62507251 chr8:50028524 T/G cg00325661 chr8:49890786 NA 0.33 7.35 0.37 1.48e-12 Blood metabolite ratios; LIHC cis rs36051895 0.632 rs2381213 chr9:5168871 A/G cg02405213 chr9:5042618 JAK2 0.55 7.96 0.4 2.51e-14 Pediatric autoimmune diseases; LIHC cis rs9640161 0.750 rs3735169 chr7:150034378 A/G cg27494647 chr7:150038898 RARRES2 0.34 6.09 0.31 2.96e-9 Blood protein levels;Circulating chemerin levels; LIHC cis rs77637988 0.578 rs11689645 chr2:48608559 G/C cg15846641 chr2:48541264 FOXN2 0.56 7.41 0.37 1.01e-12 Joint mobility (Beighton score); LIHC cis rs1707322 0.752 rs11211145 chr1:46108491 A/C cg06784218 chr1:46089804 CCDC17 0.4 7.01 0.35 1.28e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs72627123 0.867 rs117818304 chr14:74474396 T/C cg11191049 chr14:74485465 ENTPD5;C14orf45 0.65 6.08 0.31 3.27e-9 Morning vs. evening chronotype; LIHC cis rs7772486 0.534 rs34541797 chr6:146205304 A/G cg05347473 chr6:146136440 FBXO30 0.48 7.01 0.35 1.32e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs11792861 0.926 rs11788825 chr9:111829757 T/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 8.95 0.44 2.29e-17 Menarche (age at onset); LIHC cis rs4917300 0.650 rs4917268 chr8:143072510 G/A cg06573787 chr8:143070187 NA 0.28 5.82 0.3 1.38e-8 Amyotrophic lateral sclerosis; LIHC cis rs7520050 0.931 rs6688365 chr1:46329884 G/C cg01431908 chr1:46668882 C1orf190;POMGNT1 0.41 6.04 0.31 3.93e-9 Red blood cell count;Reticulocyte count; LIHC cis rs3812831 0.662 rs407531 chr13:114929218 G/A cg06611532 chr13:114900021 NA 0.43 7.85 0.39 5.38e-14 Schizophrenia; LIHC cis rs875971 0.862 rs6947339 chr7:65888470 T/C cg18876405 chr7:65276391 NA 0.34 6.23 0.32 1.35e-9 Aortic root size; LIHC cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg03264133 chr6:25882463 NA 0.88 12.25 0.55 7.2e-29 Blood metabolite levels; LIHC cis rs1949733 0.958 rs2631731 chr4:8429817 A/G cg11789530 chr4:8429930 ACOX3 0.8 11.63 0.53 1.38e-26 Response to antineoplastic agents; LIHC cis rs4689592 0.554 rs66925245 chr4:7071999 C/T cg06697600 chr4:7070879 GRPEL1 0.65 9.53 0.46 3.03e-19 Monocyte percentage of white cells; LIHC cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.43 0.62 3.28e-37 Prudent dietary pattern; LIHC cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg05564831 chr3:52568323 NT5DC2 0.37 5.9 0.3 8.72e-9 Bipolar disorder; LIHC cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.56 8.67 0.42 1.81e-16 Schizophrenia; LIHC cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg00149659 chr3:10157352 C3orf10 0.54 5.8 0.3 1.52e-8 Alzheimer's disease; LIHC cis rs4865169 0.783 rs7668814 chr4:57825190 A/G cg16868167 chr4:57843880 C4orf14;POLR2B 0.62 10.97 0.51 3.29e-24 Breast cancer; LIHC cis rs7412746 0.611 rs10888395 chr1:150762171 C/T cg18016565 chr1:150552671 MCL1 0.54 10.24 0.48 1.23e-21 Melanoma; LIHC trans rs11098499 0.675 rs11098534 chr4:120556772 T/G cg25214090 chr10:38739885 LOC399744 0.5 8.14 0.4 7.34e-15 Corneal astigmatism; LIHC cis rs11958404 0.932 rs6884954 chr5:157436772 C/T cg05962755 chr5:157440814 NA 1.07 12.05 0.55 4.01e-28 IgG glycosylation; LIHC cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg25072359 chr17:41440525 NA 0.38 5.92 0.31 7.7e-9 Menopause (age at onset); LIHC cis rs6835098 0.961 rs1574314 chr4:174106663 C/T cg27433088 chr4:174089019 GALNT7 0.41 7.01 0.35 1.25e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs10504073 0.647 rs7817571 chr8:50003218 T/C cg00325661 chr8:49890786 NA 0.31 7.12 0.36 6.58e-12 Blood metabolite ratios; LIHC cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg26338869 chr17:61819248 STRADA 0.5 6.87 0.35 3.09e-11 Height; LIHC cis rs11673344 0.542 rs826328 chr19:37495381 A/C cg27390819 chr19:37464633 NA -0.49 -6.47 -0.33 3.44e-10 Obesity-related traits; LIHC cis rs9911578 0.835 rs2301867 chr17:56480074 T/A cg12560992 chr17:57184187 TRIM37 -0.91 -15.06 -0.63 1.18e-39 Intelligence (multi-trait analysis); LIHC cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg21294424 chr19:58662284 ZNF329 0.92 7.09 0.36 7.8e-12 Cholesterol, total; LIHC cis rs703842 1.000 rs3825079 chr12:58203354 C/T cg18357645 chr12:58087776 OS9 -0.45 -6.9 -0.35 2.49e-11 Multiple sclerosis; LIHC cis rs6964587 1.000 rs10280927 chr7:91582205 G/A cg17063962 chr7:91808500 NA -1.02 -19.48 -0.73 2.17e-57 Breast cancer; LIHC cis rs8067545 0.685 rs4479309 chr17:19971583 C/T cg13482628 chr17:19912719 NA 0.48 7.93 0.39 3.24e-14 Schizophrenia; LIHC cis rs10791097 0.694 rs2155749 chr11:130751094 G/T cg12179176 chr11:130786555 SNX19 0.8 12.79 0.57 7.08e-31 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs11209002 0.567 rs2224501 chr1:67532526 G/T cg02640540 chr1:67518911 SLC35D1 0.42 5.73 0.3 2.19e-8 Crohn's disease; LIHC trans rs7714584 1.000 rs3857422 chr5:150268609 A/G cg20675040 chr8:143813288 C8orf55 0.33 6.09 0.31 3e-9 Crohn's disease; LIHC cis rs4970988 0.607 rs7548516 chr1:150980281 C/T cg18016565 chr1:150552671 MCL1 -0.35 -5.99 -0.31 5.31e-9 Urate levels; LIHC cis rs11031096 0.678 rs12223062 chr11:4180178 G/T cg18678763 chr11:4115507 RRM1 -0.42 -6.07 -0.31 3.46e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; LIHC cis rs943466 0.955 rs11757524 chr6:33766212 A/G cg25922239 chr6:33757077 LEMD2 -0.47 -5.85 -0.3 1.17e-8 Body mass index (joint analysis main effects and physical activity interaction);Body mass index; LIHC cis rs2303759 0.515 rs2334867 chr19:49788205 C/T cg22590775 chr19:49891494 CCDC155 -0.48 -7.61 -0.38 2.67e-13 Multiple sclerosis; LIHC trans rs9929218 0.954 rs7186333 chr16:68815838 T/A cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.52 -0.42 5.03e-16 Colorectal cancer; LIHC trans rs11098499 1.000 rs11098499 chr4:120187611 C/T cg25214090 chr10:38739885 LOC399744 0.5 7.72 0.39 1.28e-13 Corneal astigmatism; LIHC cis rs9633740 1.000 rs1870138 chr10:82269611 A/G cg01528321 chr10:82214614 TSPAN14 0.93 11.45 0.53 6.45e-26 Post bronchodilator FEV1; LIHC cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg11494091 chr17:61959527 GH2 0.35 5.88 0.3 1e-8 Height; LIHC cis rs79387448 0.701 rs11465586 chr2:102982709 C/G cg09003973 chr2:102972529 NA 1.13 10.56 0.5 9.25e-23 Gut microbiota (bacterial taxa); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg17861791 chr1:113162073 ST7L;CAPZA1 0.41 6.2 0.32 1.66e-9 Lung function (FEV1/FVC); LIHC cis rs6701037 0.681 rs1057246 chr1:175127534 C/G cg00958927 chr1:175162553 KIAA0040 0.36 6.12 0.31 2.63e-9 Alcohol dependence; LIHC cis rs2404602 0.669 rs17367297 chr15:77158026 A/C cg03037974 chr15:76606532 NA 0.73 14.33 0.61 8.54e-37 Blood metabolite levels; LIHC cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg08677398 chr8:58056175 NA 0.41 5.73 0.3 2.15e-8 Developmental language disorder (linguistic errors); LIHC cis rs244293 0.831 rs1948000 chr17:53147716 T/G cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.37 0.37 1.31e-12 Menarche (age at onset); LIHC cis rs7100689 0.577 rs9420359 chr10:82054873 C/T cg01528321 chr10:82214614 TSPAN14 0.88 11.96 0.54 8.49e-28 Post bronchodilator FEV1; LIHC cis rs3768617 0.528 rs6686682 chr1:183080539 A/G ch.1.3577855R chr1:183094577 LAMC1 0.6 10.44 0.49 2.42e-22 Fuchs's corneal dystrophy; LIHC cis rs9611565 0.918 rs6002351 chr22:41757223 C/T cg03806693 chr22:41940476 POLR3H -0.5 -6.44 -0.33 4.06e-10 Vitiligo; LIHC cis rs9430161 0.564 rs12081176 chr1:11034145 T/C cg02454025 chr1:11042201 C1orf127 0.96 18.34 0.7 8.49e-53 Ewing sarcoma; LIHC cis rs10751667 0.621 rs7394862 chr11:927500 T/C cg11406765 chr11:980039 AP2A2 -0.35 -5.8 -0.3 1.49e-8 Alzheimer's disease (late onset); LIHC cis rs274567 0.501 rs581968 chr5:131710202 G/A cg24060327 chr5:131705240 SLC22A5 0.79 12.43 0.56 1.53e-29 Blood metabolite levels; LIHC cis rs6430585 0.528 rs660002 chr2:136723504 C/T cg07169764 chr2:136633963 MCM6 0.97 15.31 0.64 1.18e-40 Corneal structure; LIHC cis rs7772486 0.806 rs2247317 chr6:146217570 C/T cg23711669 chr6:146136114 FBXO30 0.58 10.37 0.49 4.19e-22 Lobe attachment (rater-scored or self-reported); LIHC cis rs2288073 0.965 rs6545335 chr2:24422011 G/A cg06627628 chr2:24431161 ITSN2 -0.62 -8.23 -0.41 3.95e-15 Venous thromboembolism (SNP x SNP interaction); LIHC cis rs6912958 0.703 rs9353483 chr6:88097180 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.56 10.32 0.49 6.3e-22 Monocyte percentage of white cells; LIHC cis rs1400745 0.756 rs3783316 chr14:35337192 A/G cg05294307 chr14:35346193 BAZ1A -0.46 -7.76 -0.39 9.7e-14 Monocyte count; LIHC cis rs6121246 0.522 rs6088736 chr20:30195166 C/G cg13852791 chr20:30311386 BCL2L1 0.76 6.78 0.34 5.19e-11 Mean corpuscular hemoglobin; LIHC cis rs4820539 1.000 rs5751589 chr22:23475762 A/G cg21100191 chr22:23484243 RTDR1 -0.9 -16.65 -0.67 5.39e-46 Bone mineral density; LIHC trans rs4650994 0.525 rs11806608 chr1:178511375 T/C cg05059571 chr16:84539110 KIAA1609 -0.45 -7.64 -0.38 2.16e-13 HDL cholesterol levels;HDL cholesterol; LIHC cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg09177884 chr7:1199841 ZFAND2A -0.42 -5.79 -0.3 1.6e-8 Longevity;Endometriosis; LIHC cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg21724239 chr8:58056113 NA 0.66 10.65 0.5 4.54e-23 Developmental language disorder (linguistic errors); LIHC cis rs7412746 0.658 rs72704685 chr1:150897687 C/G cg15448220 chr1:150897856 SETDB1 0.45 7.12 0.36 6.53e-12 Melanoma; LIHC cis rs80282103 0.867 rs13377037 chr10:1068639 C/T cg18964960 chr10:1102726 WDR37 0.65 6.31 0.32 8.77e-10 Glomerular filtration rate (creatinine); LIHC cis rs9527 0.830 rs3740392 chr10:104636855 T/C cg15744005 chr10:104629667 AS3MT -0.33 -6.29 -0.32 9.91e-10 Arsenic metabolism; LIHC cis rs9309473 1.000 rs10175180 chr2:73673123 C/T cg20560298 chr2:73613845 ALMS1 -0.54 -6.83 -0.35 3.84e-11 Metabolite levels; LIHC cis rs963731 0.649 rs297137 chr2:39305721 T/C cg04010122 chr2:39346883 SOS1 -0.71 -6.33 -0.32 7.56e-10 Corticobasal degeneration; LIHC cis rs6831352 0.918 rs17218602 chr4:100061073 A/G cg12011299 chr4:100065546 ADH4 -0.63 -10.64 -0.5 4.89e-23 Alcohol dependence; LIHC cis rs60871478 0.898 rs4725241 chr7:796883 C/T cg27478167 chr7:817139 HEATR2 -0.41 -5.84 -0.3 1.25e-8 Cerebrospinal P-tau181p levels; LIHC cis rs6762 0.719 rs28655651 chr11:837121 G/C cg15787769 chr11:842744 TSPAN4;POLR2L -0.61 -7.36 -0.37 1.38e-12 Mean platelet volume; LIHC cis rs2404602 0.716 rs8030411 chr15:76699855 A/G cg03037974 chr15:76606532 NA 0.8 17.04 0.68 1.38e-47 Blood metabolite levels; LIHC cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg06634786 chr22:41940651 POLR3H 0.83 9.16 0.44 4.85e-18 Vitiligo; LIHC cis rs9814567 1.000 rs9827987 chr3:134272621 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.23 -0.55 8.89e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs847649 0.731 rs7785272 chr7:102671023 A/G cg18108683 chr7:102477205 FBXL13 -0.4 -6.11 -0.31 2.66e-9 Morning vs. evening chronotype; LIHC trans rs1005277 0.505 rs200939 chr10:38139483 T/C cg17830980 chr10:43048298 ZNF37B -0.46 -8.85 -0.43 4.65e-17 Extrinsic epigenetic age acceleration; LIHC cis rs1862618 0.671 rs252897 chr5:56223000 G/A cg24531977 chr5:56204891 C5orf35 -0.51 -7.33 -0.37 1.71e-12 Initial pursuit acceleration; LIHC cis rs11971779 0.680 rs10273527 chr7:139036598 A/C cg07862535 chr7:139043722 LUC7L2 -0.42 -7.32 -0.37 1.75e-12 Diisocyanate-induced asthma; LIHC cis rs12477438 0.798 rs9308816 chr2:99637230 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.12 -15.76 -0.65 1.97e-42 Chronic sinus infection; LIHC cis rs986417 0.901 rs1015119 chr14:61027510 G/T cg27398547 chr14:60952738 C14orf39 0.69 7.76 0.39 9.7e-14 Gut microbiota (bacterial taxa); LIHC cis rs7927771 0.524 rs10742820 chr11:47781057 C/T cg20307385 chr11:47447363 PSMC3 -0.65 -9.85 -0.47 2.68e-20 Subjective well-being; LIHC trans rs875971 1.000 rs778685 chr7:65836176 G/T cg10756647 chr7:56101905 PSPH 0.44 6.53 0.33 2.34e-10 Aortic root size; LIHC cis rs9933309 1.000 rs9933309 chr16:88844932 A/G cg27661460 chr16:88844969 FAM38A 0.4 6.55 0.33 2.17e-10 Glycated hemoglobin levels; LIHC cis rs2075371 1.000 rs2544211 chr7:133973230 A/G cg20476274 chr7:133979776 SLC35B4 0.76 13.11 0.58 4.26e-32 Mean platelet volume; LIHC trans rs7072268 0.517 rs1133189 chr10:71103597 C/G cg06648483 chr3:125802615 SLC41A3 0.48 6.32 0.32 8.25e-10 Glycated hemoglobin levels; LIHC cis rs2439831 0.850 rs7181039 chr15:44179112 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.55 7.14 0.36 5.63e-12 Lung cancer in ever smokers; LIHC trans rs17685 0.753 rs2868203 chr7:75680026 G/A cg19862616 chr7:65841803 NCRNA00174 -0.92 -19.18 -0.72 3.65e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs892961 1.000 rs2117924 chr17:75401310 C/T cg01320579 chr17:75405842 SEPT9 0.5 7.15 0.36 5.46e-12 Airflow obstruction; LIHC trans rs783540 0.967 rs783529 chr15:83267981 A/G cg18393722 chr15:85113863 UBE2QP1 -0.39 -6.75 -0.34 6.37e-11 Schizophrenia; LIHC trans rs79976124 0.837 rs11751145 chr6:66642039 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.64 6.93 0.35 2.11e-11 Type 2 diabetes; LIHC cis rs1144333 0.655 rs17097681 chr1:76376926 C/T cg03433033 chr1:76189801 ACADM 0.51 7.12 0.36 6.54e-12 Attention function in attention deficit hyperactive disorder; LIHC cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg14393609 chr7:65229607 NA 0.45 6.59 0.34 1.63e-10 Aortic root size; LIHC cis rs72781680 1.000 rs61739076 chr2:24149439 G/A cg08917208 chr2:24149416 ATAD2B 0.94 8.07 0.4 1.17e-14 Lymphocyte counts; LIHC cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg16606324 chr3:10149918 C3orf24 0.53 5.82 0.3 1.36e-8 Alzheimer's disease; LIHC cis rs6951245 0.872 rs11768895 chr7:1063691 T/C cg08132940 chr7:1081526 C7orf50 -0.67 -6.36 -0.33 6.62e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs10911232 0.507 rs11582514 chr1:182992161 T/C ch.1.3577855R chr1:183094577 LAMC1 0.61 10.5 0.49 1.53e-22 Hypertriglyceridemia; LIHC cis rs2153535 0.580 rs1120392 chr6:8487053 C/A cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs2303759 0.666 rs66967196 chr19:49808894 G/A cg22307029 chr19:49891270 CCDC155 0.55 8.53 0.42 4.89e-16 Multiple sclerosis; LIHC cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg25072359 chr17:41440525 NA 0.39 6.2 0.32 1.59e-9 Menopause (age at onset); LIHC cis rs1882538 0.538 rs7803848 chr7:133108547 C/T cg10665199 chr7:133106180 EXOC4 0.5 8.24 0.41 3.77e-15 Intelligence (multi-trait analysis); LIHC cis rs738322 0.511 rs5756947 chr22:38573230 G/A cg25457927 chr22:38595422 NA -0.37 -8.79 -0.43 7.33e-17 Cutaneous nevi; LIHC cis rs10504229 1.000 rs111915672 chr8:58191665 T/C cg02290350 chr8:58132656 NA 0.41 8.36 0.41 1.65e-15 Developmental language disorder (linguistic errors); LIHC cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg12311346 chr5:56204834 C5orf35 -0.58 -7.56 -0.38 3.81e-13 Initial pursuit acceleration; LIHC cis rs7582720 0.943 rs72934762 chr2:203756677 G/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg22974920 chr21:40686053 BRWD1 -0.4 -5.76 -0.3 1.83e-8 Cognitive function; LIHC cis rs9560113 0.508 rs2774425 chr13:112235077 A/G cg10483660 chr13:112241077 NA -0.24 -6.27 -0.32 1.1e-9 Menarche (age at onset); LIHC cis rs7666738 0.830 rs10031190 chr4:98908683 C/A cg05340658 chr4:99064831 C4orf37 0.65 11.87 0.54 1.94e-27 Colonoscopy-negative controls vs population controls; LIHC cis rs11204677 1 rs11204677 chr1:150574695 C/G cg18016565 chr1:150552671 MCL1 -0.54 -11.08 -0.51 1.36e-24 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27403822 chr1:179050983 TOR3A 0.42 6.71 0.34 8.23e-11 Cognitive function; LIHC cis rs8077889 1.000 rs2079005 chr17:41865627 T/G cg26893861 chr17:41843967 DUSP3 1.03 11.15 0.52 7.78e-25 Triglycerides; LIHC cis rs7216064 1.000 rs6504549 chr17:65888784 A/G cg12091567 chr17:66097778 LOC651250 -0.67 -9.68 -0.46 9.84e-20 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg21724239 chr8:58056113 NA 0.57 7.62 0.38 2.58e-13 Developmental language disorder (linguistic errors); LIHC cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg12310025 chr6:25882481 NA -0.65 -9.27 -0.45 2.14e-18 Blood metabolite levels; LIHC cis rs754466 0.580 rs2579176 chr10:79529350 A/G cg17075019 chr10:79541650 NA -0.79 -11.94 -0.54 1.07e-27 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs703842 0.642 rs11536137 chr12:58056426 C/A cg04478727 chr12:58166393 METTL1;FAM119B 0.56 7.64 0.38 2.22e-13 Multiple sclerosis; LIHC cis rs709400 0.663 rs10133035 chr14:103979127 C/T cg26031613 chr14:104095156 KLC1 0.72 9.14 0.44 5.86e-18 Body mass index; LIHC cis rs1062177 0.756 rs2915827 chr5:151119705 T/A cg00977110 chr5:151150581 G3BP1 -0.56 -7.08 -0.36 8.48e-12 Preschool internalizing problems; LIHC cis rs7615952 0.599 rs6803160 chr3:125709554 G/T cg05084668 chr3:125655381 ALG1L -0.43 -7.05 -0.36 9.73e-12 Blood pressure (smoking interaction); LIHC cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg06481639 chr22:41940642 POLR3H 0.71 7.43 0.37 8.87e-13 Vitiligo; LIHC cis rs6448317 0.954 rs7666033 chr4:24925272 A/G cg21108841 chr4:24914750 CCDC149 -0.49 -6.19 -0.32 1.74e-9 Heschl's gyrus morphology; LIHC cis rs655641 1.000 rs600258 chr11:85710169 G/A cg09030501 chr11:85779252 PICALM -0.51 -6.16 -0.32 1.99e-9 Platelet count; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26818935 chr16:740532 WDR24 0.43 6.05 0.31 3.8e-9 Lung function (FEV1/FVC); LIHC cis rs748404 0.697 rs567357 chr15:43571390 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.48 8.15 0.4 6.82e-15 Lung cancer; LIHC cis rs2935183 1 rs2935183 chr17:45607572 T/G cg08085267 chr17:45401833 C17orf57 0.56 8.29 0.41 2.59e-15 Multiple sclerosis or amyotrophic lateral sclerosis; LIHC trans rs3783890 0.887 rs11629303 chr14:93810048 G/A cg02802420 chr16:69363236 PDF;COG8 0.33 6.29 0.32 9.66e-10 Body mass index; LIHC cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg12310025 chr6:25882481 NA 0.57 7.71 0.38 1.35e-13 Blood metabolite levels; LIHC cis rs477692 0.549 rs7079744 chr10:131454790 G/A cg19680672 chr10:131412579 MGMT 0.42 6.54 0.33 2.23e-10 Response to temozolomide; LIHC cis rs9303401 0.659 rs11495824 chr17:56918882 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.93 12.6 0.56 3.51e-30 Cognitive test performance; LIHC cis rs1419980 0.730 rs11054887 chr12:7772997 G/A cg10578777 chr12:7781093 NA -0.39 -5.82 -0.3 1.38e-8 HDL cholesterol levels; LIHC cis rs72627123 0.867 rs113257091 chr14:74461121 C/T cg12022184 chr14:74485813 ENTPD5;C14orf45 0.85 8.17 0.4 6.07e-15 Morning vs. evening chronotype; LIHC cis rs8062405 1.000 rs1987472 chr16:28825777 C/T cg00204512 chr16:28754710 NA 0.36 6.71 0.34 7.92e-11 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9814567 1.000 rs9832785 chr3:134213070 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.88 -0.3 9.96e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8038465 0.789 rs57909886 chr15:73973662 T/C cg15420318 chr15:73925796 NPTN 0.39 5.94 0.31 7e-9 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs903552 1.000 rs4965872 chr15:102004002 C/T cg06707286 chr15:102010195 PCSK6 -0.44 -6.26 -0.32 1.17e-9 Diabetic kidney disease; LIHC cis rs4555082 1.000 rs4334224 chr14:105759198 C/T cg06808227 chr14:105710500 BRF1 -0.49 -6.49 -0.33 3.08e-10 Mean platelet volume;Platelet distribution width; LIHC cis rs7086627 0.515 rs10887899 chr10:82210214 G/A cg01528321 chr10:82214614 TSPAN14 0.53 7.38 0.37 1.24e-12 Post bronchodilator FEV1; LIHC cis rs2067615 0.542 rs4964184 chr12:107070425 A/T cg15890332 chr12:107067104 RFX4 0.26 6.3 0.32 9.05e-10 Heart rate; LIHC cis rs950776 0.616 rs6495307 chr15:78890321 C/T cg06917634 chr15:78832804 PSMA4 0.64 8.91 0.43 3.17e-17 Sudden cardiac arrest; LIHC cis rs1801251 1.000 rs1867778 chr2:233679644 C/T cg08000102 chr2:233561755 GIGYF2 -0.75 -11.33 -0.52 1.73e-25 Coronary artery disease; LIHC trans rs2235573 0.551 rs139891 chr22:38387914 G/T cg19894588 chr14:64061835 NA 0.49 6.67 0.34 1.04e-10 Glioblastoma;Glioma; LIHC cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.97 8.67 0.42 1.73e-16 Platelet count; LIHC cis rs6701037 0.566 rs4344281 chr1:175135376 C/T cg17845761 chr1:175162550 KIAA0040 0.41 6.81 0.35 4.52e-11 Alcohol dependence; LIHC cis rs10751667 0.643 rs7396623 chr11:934104 G/A cg11406765 chr11:980039 AP2A2 -0.34 -5.74 -0.3 2.06e-8 Alzheimer's disease (late onset); LIHC cis rs1005277 0.579 rs2472183 chr10:38392495 T/G cg25427524 chr10:38739819 LOC399744 -0.64 -12.11 -0.55 2.57e-28 Extrinsic epigenetic age acceleration; LIHC cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg20102877 chr2:27665638 KRTCAP3 -0.42 -5.83 -0.3 1.26e-8 Total body bone mineral density; LIHC cis rs5753618 0.509 rs5997912 chr22:31593861 A/G cg07713946 chr22:31675144 LIMK2 -0.42 -7.38 -0.37 1.18e-12 Colorectal cancer; LIHC cis rs2463822 0.764 rs7125402 chr11:62097259 C/T cg06239285 chr11:62104954 ASRGL1 0.93 7.14 0.36 5.5e-12 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs7552404 1.000 rs11161510 chr1:76210289 A/G cg10523679 chr1:76189770 ACADM -0.63 -8.63 -0.42 2.29e-16 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg19318889 chr4:1322082 MAEA 0.39 6.43 0.33 4.42e-10 Obesity-related traits; LIHC cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg20607798 chr8:58055168 NA -0.62 -8.02 -0.4 1.7e-14 Developmental language disorder (linguistic errors); LIHC cis rs1355223 0.583 rs2941058 chr11:34880245 C/G cg06937548 chr11:34938143 PDHX;APIP 0.42 6.04 0.31 3.97e-9 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs72781680 0.821 rs12616257 chr2:24135034 A/G cg08917208 chr2:24149416 ATAD2B 0.64 6.44 0.33 4.1e-10 Lymphocyte counts; LIHC cis rs17401966 1.000 rs12402052 chr1:10318652 C/G cg15208524 chr1:10270712 KIF1B 0.45 6.43 0.33 4.32e-10 Hepatocellular carcinoma; LIHC cis rs2257205 0.667 rs28605629 chr17:56906157 C/A cg12560992 chr17:57184187 TRIM37 0.67 7.23 0.36 3.24e-12 Pancreatic cancer; LIHC cis rs8060686 0.545 rs12600062 chr16:68287544 C/A cg09835421 chr16:68378352 PRMT7 -0.57 -6.58 -0.34 1.81e-10 HDL cholesterol;Metabolic syndrome; LIHC cis rs1144333 0.655 rs76175698 chr1:76454792 C/T cg03433033 chr1:76189801 ACADM 0.53 7.45 0.37 7.94e-13 Attention function in attention deficit hyperactive disorder; LIHC cis rs919433 0.713 rs11900232 chr2:198466273 T/C cg10820045 chr2:198174542 NA 0.51 7.98 0.4 2.16e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7914558 1.000 rs7077097 chr10:104945463 G/A cg15744005 chr10:104629667 AS3MT -0.38 -8.55 -0.42 4.22e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs34779708 0.931 rs4934700 chr10:35310842 A/G cg03585969 chr10:35415529 CREM 0.86 12.92 0.57 2.29e-31 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9814567 1.000 rs9809619 chr3:134280948 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -12.17 -0.55 1.52e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg26888861 chr11:62521812 ZBTB3 -0.47 -6.32 -0.32 7.92e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2624839 0.679 rs2624835 chr3:50209049 G/A cg24110177 chr3:50126178 RBM5 -0.48 -5.73 -0.3 2.23e-8 Intelligence (multi-trait analysis); LIHC cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg12310025 chr6:25882481 NA -0.47 -7.2 -0.36 3.93e-12 Height; LIHC cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg06634786 chr22:41940651 POLR3H -0.77 -7.37 -0.37 1.27e-12 Vitiligo; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg06684987 chr19:45567721 SFRS16 0.44 6.23 0.32 1.41e-9 Bilirubin levels; LIHC cis rs965469 1.000 rs6139068 chr20:3284393 G/A cg25506879 chr20:3388711 C20orf194 -0.6 -6.91 -0.35 2.43e-11 IFN-related cytopenia; LIHC trans rs1814175 0.702 rs4881644 chr11:49786367 C/T cg18944383 chr4:111397179 ENPEP 0.28 7.09 0.36 7.87e-12 Height; LIHC cis rs9952991 0.883 rs2542148 chr18:12777573 C/G cg23598886 chr18:12777645 NA 0.48 6.51 0.33 2.75e-10 Inflammatory skin disease; LIHC cis rs875971 0.619 rs12533585 chr7:65984605 G/C cg14393609 chr7:65229607 NA 0.37 5.81 0.3 1.4e-8 Aortic root size; LIHC cis rs6545883 0.894 rs35292974 chr2:61522047 T/C cg15711740 chr2:61764176 XPO1 0.42 5.78 0.3 1.67e-8 Tuberculosis; LIHC cis rs240764 0.658 rs35967345 chr6:101187858 T/G cg12253828 chr6:101329408 ASCC3 -0.39 -5.95 -0.31 6.78e-9 Neuroticism; LIHC cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg27432699 chr2:27873401 GPN1 -0.5 -7.27 -0.37 2.39e-12 Total body bone mineral density; LIHC cis rs929354 0.772 rs1182438 chr7:157027438 G/A cg16102536 chr7:156981717 UBE3C -0.35 -5.81 -0.3 1.41e-8 Body mass index; LIHC trans rs7618501 1.000 rs3811696 chr3:49761605 C/T cg21659725 chr3:3221576 CRBN -0.98 -19.55 -0.73 1.14e-57 Intelligence (multi-trait analysis); LIHC cis rs600806 0.627 rs2359652 chr1:110008720 T/A cg23091122 chr1:110024289 SYPL2 -0.47 -6.36 -0.33 6.47e-10 Intelligence (multi-trait analysis); LIHC cis rs7937682 0.921 rs10789841 chr11:111469582 T/C cg09085632 chr11:111637200 PPP2R1B 0.87 10.01 0.48 7.57e-21 Primary sclerosing cholangitis; LIHC cis rs12477438 0.765 rs7607578 chr2:99669771 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC trans rs2243480 0.908 rs313822 chr7:65573939 G/A cg10756647 chr7:56101905 PSPH 1.07 13.4 0.59 3.25e-33 Diabetic kidney disease; LIHC cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs11098499 0.789 rs10212719 chr4:120254437 T/C cg25214090 chr10:38739885 LOC399744 0.51 8.23 0.41 3.93e-15 Corneal astigmatism; LIHC cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg26338869 chr17:61819248 STRADA 0.57 8.29 0.41 2.55e-15 Prudent dietary pattern; LIHC cis rs425277 0.628 rs3107147 chr1:2048729 G/A cg04315214 chr1:2043799 PRKCZ 0.45 7.15 0.36 5.21e-12 Height; LIHC cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg02290350 chr8:58132656 NA 0.52 11.2 0.52 5.33e-25 Developmental language disorder (linguistic errors); LIHC cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg11890956 chr21:40555474 PSMG1 -0.49 -8.15 -0.4 7.02e-15 Menarche (age at onset); LIHC cis rs6582630 0.502 rs4559747 chr12:38436235 G/A cg26384229 chr12:38710491 ALG10B 0.59 8.25 0.41 3.5e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 9.98 0.47 9.29e-21 Platelet count; LIHC cis rs2404602 0.692 rs55729975 chr15:76803226 G/A cg03037974 chr15:76606532 NA 0.73 14.04 0.6 1.08e-35 Blood metabolite levels; LIHC cis rs10779751 1.000 rs4845982 chr1:11271576 T/C cg08854313 chr1:11322531 MTOR 0.82 11.46 0.53 6.12e-26 Body mass index; LIHC cis rs6726292 1.000 rs4399760 chr2:55157492 A/C cg09592903 chr2:55203963 RTN4 0.37 5.77 0.3 1.77e-8 Obesity (extreme); LIHC cis rs7772486 0.846 rs1331636 chr6:146338826 T/C cg23711669 chr6:146136114 FBXO30 0.67 11.83 0.54 2.59e-27 Lobe attachment (rater-scored or self-reported); LIHC cis rs1185460 0.804 rs13929 chr11:118915755 G/C cg23280166 chr11:118938394 VPS11 0.46 6.33 0.32 7.74e-10 Coronary artery disease; LIHC cis rs1348850 0.539 rs1453371 chr2:178227862 T/G cg02961200 chr2:178257176 LOC100130691;AGPS 0.8 12.17 0.55 1.45e-28 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs12477438 0.798 rs12473029 chr2:99637961 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -11.26 -0.52 3.12e-25 Chronic sinus infection; LIHC trans rs11689435 0.925 rs1478588 chr2:218338149 G/A cg13544946 chr9:35729779 TLN1 -0.44 -6.22 -0.32 1.43e-9 Metabolite levels (MHPG); LIHC cis rs6977660 0.943 rs10277755 chr7:19826843 C/A cg07541023 chr7:19748670 TWISTNB 0.37 5.77 0.3 1.77e-8 Thyroid stimulating hormone; LIHC cis rs72627123 0.656 rs117129791 chr14:74520871 G/A cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 5.78 0.3 1.69e-8 Morning vs. evening chronotype; LIHC cis rs782590 0.935 rs782652 chr2:55862775 C/A cg03859395 chr2:55845619 SMEK2 0.91 15.95 0.65 3.4e-43 Metabolic syndrome; LIHC cis rs2599510 0.811 rs176410 chr2:32643437 C/G cg02381751 chr2:32503542 YIPF4 -0.46 -6.51 -0.33 2.64e-10 Interleukin-18 levels; LIHC cis rs10733682 0.524 rs10987419 chr9:129462594 T/C cg00232160 chr9:129468157 NA 0.39 6.95 0.35 1.84e-11 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7903847 0.642 rs61863819 chr10:99142400 T/C cg06359132 chr10:99160096 RRP12 -0.43 -6.65 -0.34 1.16e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs10927875 0.830 rs1763610 chr1:16335527 C/G cg21385522 chr1:16154831 NA -0.72 -9.36 -0.45 1.11e-18 Dilated cardiomyopathy; LIHC cis rs7520050 0.966 rs6656992 chr1:46333068 C/G cg03146154 chr1:46216737 IPP -0.39 -6.48 -0.33 3.21e-10 Red blood cell count;Reticulocyte count; LIHC cis rs921968 0.643 rs497983 chr2:219415189 A/G cg18887096 chr2:219472410 PLCD4 0.39 6.81 0.35 4.53e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs2073300 0.609 rs6137919 chr20:23363163 T/C cg12062639 chr20:23401060 NAPB 1.08 14.41 0.61 4.14e-37 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1577917 0.655 rs2758849 chr6:86344296 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.3 -0.41 2.53e-15 Response to antipsychotic treatment; LIHC trans rs9929218 0.953 rs34909703 chr16:68740097 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.65 -9.53 -0.46 2.98e-19 Colorectal cancer; LIHC cis rs6445975 0.715 rs17059125 chr3:58268750 C/A cg23715586 chr3:58305044 RPP14 -0.38 -6.32 -0.32 8.25e-10 Systemic lupus erythematosus; LIHC cis rs9649465 0.561 rs2429620 chr7:123430012 A/G cg03229431 chr7:123269106 ASB15 0.42 9.12 0.44 6.51e-18 Migraine; LIHC cis rs7618501 0.602 rs34831713 chr3:50118748 T/C cg24110177 chr3:50126178 RBM5 0.53 8.66 0.42 1.91e-16 Intelligence (multi-trait analysis); LIHC cis rs1865721 0.761 rs7242709 chr18:73222819 T/C cg26385618 chr18:73139727 C18orf62 -0.27 -6.78 -0.34 5.41e-11 Intelligence; LIHC cis rs7762018 0.891 rs7740218 chr6:170141552 G/A cg13891659 chr6:170190454 C6orf122;C6orf208 0.51 6.21 0.32 1.53e-9 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs7246657 0.943 rs1015849 chr19:37946180 G/A cg23950597 chr19:37808831 NA -0.5 -6.46 -0.33 3.52e-10 Coronary artery calcification; LIHC cis rs35160687 0.644 rs57270703 chr2:86516873 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 0.37 6.01 0.31 4.71e-9 Night sleep phenotypes; LIHC cis rs7618501 1.000 rs4855862 chr3:49748833 C/T cg21467203 chr3:49911342 NA 0.4 7.01 0.35 1.25e-11 Intelligence (multi-trait analysis); LIHC cis rs240764 0.853 rs2062635 chr6:101002659 G/A cg09795085 chr6:101329169 ASCC3 -0.47 -6.22 -0.32 1.43e-9 Neuroticism; LIHC cis rs8016982 0.633 rs7141288 chr14:81710232 C/A cg01989461 chr14:81687754 GTF2A1 0.72 14.41 0.61 4.22e-37 Schizophrenia; LIHC cis rs7716219 0.572 rs55835145 chr5:54868559 A/C cg14753740 chr5:54468940 CDC20B;MIR449C 0.45 6.25 0.32 1.22e-9 Height; LIHC cis rs12477438 0.798 rs1530996 chr2:99584079 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -1.09 -15.97 -0.65 2.73e-43 Chronic sinus infection; LIHC cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg20570016 chr1:156261298 TMEM79 0.38 6.13 0.31 2.47e-9 Tonsillectomy; LIHC cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg21782813 chr7:2030301 MAD1L1 -0.54 -10.05 -0.48 5.3e-21 Bipolar disorder and schizophrenia; LIHC trans rs1552244 0.572 rs58223482 chr3:10169746 G/C cg26113512 chr3:38035601 VILL -0.53 -6.08 -0.31 3.25e-9 Alzheimer's disease; LIHC cis rs35306767 0.903 rs11816064 chr10:931176 A/C cg26597838 chr10:835615 NA 1.14 13.93 0.6 2.98e-35 Eosinophil percentage of granulocytes; LIHC cis rs3789045 0.819 rs16854023 chr1:204551830 A/G cg17419461 chr1:204415978 PIK3C2B -0.42 -6.58 -0.34 1.77e-10 Educational attainment (college completion); LIHC cis rs2549003 1.000 rs9282762 chr5:131822055 T/C cg02551604 chr5:131831745 NA -0.43 -6.5 -0.33 2.91e-10 Asthma (sex interaction); LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg22528358 chr1:107598549 PRMT6 0.69 11.28 0.52 2.61e-25 Facial morphology (factor 21, depth of nasal alae); LIHC trans rs3749237 1.000 rs6804655 chr3:49738945 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.64 9.89 0.47 1.9e-20 Resting heart rate; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26805528 chr9:131872542 CRAT;PPP2R4 0.4 6.56 0.33 2.01e-10 Cognitive function; LIHC cis rs7582180 0.739 rs11687352 chr2:100919888 A/C cg14675211 chr2:100938903 LONRF2 0.52 7.91 0.39 3.53e-14 Intelligence (multi-trait analysis); LIHC cis rs1185460 0.967 rs3825061 chr11:118944675 C/T cg23280166 chr11:118938394 VPS11 0.56 7.2 0.36 3.91e-12 Coronary artery disease; LIHC cis rs8027181 0.839 rs998021 chr15:72999825 T/C cg25632853 chr15:73088954 NA 0.36 5.96 0.31 6.41e-9 Triglyceride levels; LIHC cis rs6701037 0.681 rs13374887 chr1:175131962 A/T cg00321850 chr1:175162397 KIAA0040 0.42 6.77 0.34 5.77e-11 Alcohol dependence; LIHC cis rs644799 0.544 rs687559 chr11:95598629 C/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.57 -7.97 -0.4 2.46e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs7131987 0.868 rs7958210 chr12:29395181 G/C cg00204748 chr12:29376779 FAR2 0.46 8.71 0.43 1.35e-16 QT interval; LIHC cis rs17345786 0.628 rs11718446 chr3:101552553 C/T cg11279151 chr3:101281821 RG9MTD1 -0.46 -6.71 -0.34 8.02e-11 Colonoscopy-negative controls vs population controls; LIHC trans rs723794 0.598 rs6855750 chr4:146980183 T/C cg22222663 chr11:117800467 TMPRSS13 0.22 6.05 0.31 3.81e-9 Smooth-surface caries; LIHC cis rs6089584 1.000 rs6089580 chr20:60558976 G/A cg12751644 chr20:60527061 NA -0.37 -6.09 -0.31 3.12e-9 Body mass index; LIHC cis rs3008870 0.959 rs2985808 chr1:67367741 T/C cg02640540 chr1:67518911 SLC35D1 0.44 6.07 0.31 3.47e-9 Lymphocyte percentage of white cells; LIHC cis rs2576037 0.583 rs593340 chr18:44418346 C/T cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.42 -5.91 -0.3 8.31e-9 Personality dimensions; LIHC trans rs9531686 1.000 rs9531686 chr13:85549736 T/G cg11095898 chr11:93466424 SNORA1;SNORA8;SNORD5 0.32 6.25 0.32 1.19e-9 Anorexia nervosa; LIHC cis rs6545883 0.868 rs6748003 chr2:61806700 T/G cg14146966 chr2:61757674 XPO1 0.46 7.88 0.39 4.44e-14 Tuberculosis; LIHC cis rs1707322 1.000 rs785484 chr1:46574015 T/C cg06784218 chr1:46089804 CCDC17 -0.4 -7.22 -0.36 3.38e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6690583 0.623 rs1371141 chr1:85455372 C/A cg22153463 chr1:85462885 MCOLN2 0.49 5.91 0.3 8.45e-9 Serum sulfate level; LIHC cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.73 12.54 0.56 6.2e-30 Colorectal cancer; LIHC cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg02475777 chr4:1388615 CRIPAK -0.55 -7.78 -0.39 8.67e-14 Longevity; LIHC cis rs4727027 0.901 rs66800495 chr7:148763702 T/C cg23583168 chr7:148888333 NA -0.67 -9.22 -0.45 3.16e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs6430585 0.583 rs2304370 chr2:136561735 G/A cg15123519 chr2:136567270 LCT -0.41 -6.92 -0.35 2.3e-11 Corneal structure; LIHC cis rs1055129 0.560 rs2666003 chr17:73942976 G/A cg19302996 chr17:73780495 UNK -0.47 -6.75 -0.34 6.2e-11 White matter hyperintensity burden; LIHC cis rs7312933 0.612 rs10785334 chr12:42620377 A/G cg17420585 chr12:42539391 GXYLT1 0.38 6.04 0.31 4.05e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg18305652 chr10:134549665 INPP5A 0.52 8.09 0.4 1.08e-14 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC trans rs2727020 0.729 rs6485965 chr11:49166730 C/T cg03929089 chr4:120376271 NA 0.76 13.4 0.59 3.4e-33 Coronary artery disease; LIHC cis rs9473924 0.505 rs9473949 chr6:50909659 T/A cg14470998 chr6:50812995 TFAP2B 0.91 10.51 0.49 1.39e-22 Body mass index; LIHC cis rs1129187 0.748 rs6458312 chr6:42904274 G/T cg10862848 chr6:42927986 GNMT -0.26 -6.41 -0.33 4.93e-10 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.65 11.92 0.54 1.29e-27 Prudent dietary pattern; LIHC cis rs12744310 1.000 rs55859000 chr1:41761441 T/C cg03962019 chr1:41807865 NA 0.38 6.2 0.32 1.67e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs1552244 0.751 rs12715665 chr3:10021601 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.69 -11.01 -0.51 2.51e-24 Alzheimer's disease; LIHC cis rs35110281 0.591 rs230642 chr21:44915533 A/C cg04455712 chr21:45112962 RRP1B -0.4 -6.72 -0.34 7.72e-11 Mean corpuscular volume; LIHC cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.48 6.49 0.33 3.02e-10 Bipolar disorder; LIHC cis rs4073582 0.595 rs801739 chr11:65922589 A/G cg14036092 chr11:66035641 RAB1B 0.38 6.04 0.31 4.06e-9 Gout; LIHC cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg00656387 chr3:40428638 ENTPD3 -0.5 -8.53 -0.42 4.94e-16 Renal cell carcinoma; LIHC cis rs17685 0.735 rs11763339 chr7:75761541 T/C cg16684958 chr7:75615977 POR 0.52 8.67 0.42 1.8e-16 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs9517313 0.523 rs4772104 chr13:99235677 G/A cg20487152 chr13:99095054 FARP1 -0.37 -6.04 -0.31 4.01e-9 Neuroticism; LIHC cis rs5758511 0.689 rs45441993 chr22:42471738 C/A cg00645731 chr22:42541494 CYP2D7P1 0.62 5.91 0.3 8.12e-9 Birth weight; LIHC cis rs8038465 0.568 rs62004592 chr15:73878019 A/G cg15420318 chr15:73925796 NPTN 0.48 7.14 0.36 5.71e-12 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg27367952 chr2:219221586 C2orf62 0.42 6.5 0.33 2.79e-10 Cognitive function; LIHC cis rs919433 0.963 rs4850430 chr2:198182796 A/T cg03934865 chr2:198174659 NA -0.57 -9.09 -0.44 8e-18 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7552404 1.000 rs4949674 chr1:76213715 C/A cg22875332 chr1:76189707 ACADM 0.49 7.29 0.37 2.2e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg13395646 chr4:1353034 KIAA1530 -0.48 -7.55 -0.38 4e-13 Obesity-related traits; LIHC cis rs11098499 0.562 rs58583086 chr4:120556362 A/G cg09307838 chr4:120376055 NA -0.57 -8.74 -0.43 1.04e-16 Corneal astigmatism; LIHC cis rs1816752 0.683 rs7330532 chr13:25017591 C/T cg22771759 chr13:24902376 NA 0.31 6.47 0.33 3.49e-10 Obesity-related traits; LIHC cis rs7927592 0.956 rs12281742 chr11:68303629 C/T cg16797656 chr11:68205561 LRP5 -0.54 -8.8 -0.43 6.84e-17 Total body bone mineral density; LIHC cis rs4888262 0.508 rs7189123 chr16:74540097 C/A cg01733217 chr16:74700730 RFWD3 0.75 14.16 0.61 3.95e-36 Testicular germ cell tumor; LIHC cis rs10751667 0.961 rs7395928 chr11:952605 T/G cg06064525 chr11:970664 AP2A2 -0.5 -12.49 -0.56 9.64e-30 Alzheimer's disease (late onset); LIHC cis rs79149102 0.579 rs7163390 chr15:75280426 T/C cg17294928 chr15:75287854 SCAMP5 -0.49 -6.38 -0.33 5.62e-10 Lung cancer; LIHC trans rs9403317 0.573 rs9389941 chr6:141990680 T/C cg23847162 chr6:15663024 DTNBP1 0.55 6.16 0.32 2.02e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs4853012 0.941 rs7571083 chr2:74342260 C/G cg23149560 chr2:74406255 MOBKL1B 0.41 5.85 0.3 1.12e-8 Gestational age at birth (maternal effect); LIHC cis rs3806843 1.000 rs10038174 chr5:140210616 G/A cg26395211 chr5:140044315 WDR55 -0.42 -6.21 -0.32 1.49e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs7296418 0.663 rs11057284 chr12:123830692 G/C cg05973401 chr12:123451056 ABCB9 0.41 6.28 0.32 1.02e-9 Platelet count; LIHC cis rs780096 0.545 rs11695549 chr2:27586155 A/C cg22903471 chr2:27725779 GCKR -0.5 -8.55 -0.42 4.14e-16 Total body bone mineral density; LIHC cis rs9457247 1.000 rs422694 chr6:167406074 G/T cg12798992 chr6:167411361 FGFR1OP 0.6 9.92 0.47 1.51e-20 Crohn's disease; LIHC cis rs7131987 0.650 rs7311912 chr12:29475703 G/C cg05697976 chr12:29376483 FAR2 0.31 6.2 0.32 1.62e-9 QT interval; LIHC cis rs898097 0.812 rs7406011 chr17:80829980 C/T cg15369054 chr17:80825471 TBCD 0.45 6.42 0.33 4.6e-10 Breast cancer; LIHC cis rs12477438 0.539 rs12999417 chr2:99865548 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.83 -12.57 -0.56 4.6e-30 Chronic sinus infection; LIHC cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.69 -11.75 -0.54 5.31e-27 Menarche (age at onset); LIHC cis rs7224737 1.000 rs9903204 chr17:40288062 G/A cg02450064 chr17:40260053 DHX58 -0.29 -6.02 -0.31 4.46e-9 Fibrinogen levels; LIHC cis rs7592578 0.882 rs7569128 chr2:191446691 C/A cg10560079 chr2:191398806 TMEM194B 0.88 12.09 0.55 3.01e-28 Diastolic blood pressure; LIHC cis rs7772486 0.875 rs9403764 chr6:146360582 G/A cg13319975 chr6:146136371 FBXO30 -0.36 -5.97 -0.31 6.03e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg15586420 chr15:90294517 MESP1 0.45 7.18 0.36 4.49e-12 Cognitive function; LIHC cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg08888203 chr3:10149979 C3orf24 0.54 6.27 0.32 1.06e-9 Alzheimer's disease; LIHC cis rs2384207 1.000 rs2384207 chr12:113607502 T/C cg22376712 chr12:113623594 C12orf52;DDX54 0.48 5.88 0.3 9.97e-9 Response to fenofibrate (adiponectin levels); LIHC cis rs208346 0.612 rs208356 chr7:2775825 A/T cg18446336 chr7:2847575 GNA12 0.37 7.13 0.36 6.17e-12 Loneliness (linear analysis); LIHC cis rs7412746 0.611 rs11803940 chr1:150685835 A/G cg17724175 chr1:150552817 MCL1 0.49 9.89 0.47 1.92e-20 Melanoma; LIHC cis rs9814567 0.964 rs9847788 chr3:134186496 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.55 -10.24 -0.48 1.21e-21 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg05564831 chr3:52568323 NT5DC2 0.37 6.01 0.31 4.66e-9 Bipolar disorder; LIHC cis rs7116495 0.609 rs579254 chr11:71582544 T/C cg26138937 chr11:71823887 C11orf51 0.7 6.79 0.34 4.87e-11 Severe influenza A (H1N1) infection; LIHC trans rs1005277 0.579 rs2474575 chr10:38387901 C/T cg27523141 chr10:43048294 ZNF37B 0.36 6.23 0.32 1.35e-9 Extrinsic epigenetic age acceleration; LIHC cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg05368731 chr17:41323189 NBR1 0.73 12.58 0.56 4.43e-30 Menopause (age at onset); LIHC cis rs16944613 0.510 rs11636695 chr15:91152911 C/G cg26821196 chr15:91095069 CRTC3 -0.35 -6.4 -0.33 5.1e-10 Colorectal cancer; LIHC cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg05368731 chr17:41323189 NBR1 0.73 12.56 0.56 5.19e-30 Menopause (age at onset); LIHC cis rs6424115 0.729 rs1737362 chr1:24054800 T/C cg15997130 chr1:24165203 NA 0.34 6.75 0.34 6.24e-11 Immature fraction of reticulocytes; LIHC cis rs7945705 0.520 rs1984791 chr11:9035027 C/T cg12365402 chr11:9010492 NRIP3 0.3 7.24 0.36 3.07e-12 Hemoglobin concentration; LIHC cis rs951366 0.668 rs823154 chr1:205762406 C/T cg11965913 chr1:205819406 PM20D1 0.64 9.28 0.45 1.92e-18 Menarche (age at onset); LIHC cis rs3820068 0.705 rs4646077 chr1:15827136 C/T cg17385448 chr1:15911702 AGMAT 0.37 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs9303280 0.806 rs12941333 chr17:38040534 C/T cg11212589 chr17:38028394 ZPBP2 0.35 7.1 0.36 7.36e-12 Self-reported allergy; LIHC cis rs1552244 0.572 rs58223482 chr3:10169746 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.87 -10.64 -0.5 4.9e-23 Alzheimer's disease; LIHC cis rs6732160 0.657 rs10171459 chr2:73434728 A/C cg24220031 chr2:73402428 NA -0.27 -5.85 -0.3 1.13e-8 Intelligence (multi-trait analysis); LIHC cis rs7520050 0.931 rs11211224 chr1:46384388 G/A cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg05896524 chr21:47604654 C21orf56 0.45 6.71 0.34 7.97e-11 Testicular germ cell tumor; LIHC cis rs7582720 0.511 rs116219813 chr2:204081675 C/T cg15057621 chr2:203777863 WDR12;ALS2CR8 0.76 6.13 0.31 2.36e-9 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg18230493 chr5:56204884 C5orf35 -0.47 -6.49 -0.33 2.96e-10 Initial pursuit acceleration; LIHC cis rs2816062 0.813 rs2816057 chr1:18902257 G/C cg18795169 chr1:18902165 NA -0.8 -17.53 -0.69 1.53e-49 Urate levels in lean individuals; LIHC cis rs7546668 0.947 rs3737705 chr1:15911349 G/A cg11706911 chr1:15910989 AGMAT 0.47 7.16 0.36 4.85e-12 Glomerular filtration rate (creatinine); LIHC cis rs7551222 0.662 rs4951399 chr1:204533255 G/A cg20240347 chr1:204465584 NA -0.34 -7.08 -0.36 8.14e-12 Schizophrenia; LIHC cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg06634786 chr22:41940651 POLR3H 0.83 8.89 0.43 3.5e-17 Vitiligo; LIHC cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.14 17.77 0.69 1.59e-50 Gut microbiome composition (summer); LIHC trans rs10411161 0.702 rs10414472 chr19:52398597 C/T cg22319618 chr22:45562946 NUP50 -0.61 -8.31 -0.41 2.25e-15 Breast cancer; LIHC cis rs3768617 0.782 rs12146099 chr1:182968079 G/A ch.1.3577855R chr1:183094577 LAMC1 0.44 6.71 0.34 8.08e-11 Fuchs's corneal dystrophy; LIHC cis rs861020 0.677 rs2049998 chr1:210031154 C/T cg05527609 chr1:210001259 C1orf107 -0.91 -12.21 -0.55 1.01e-28 Orofacial clefts; LIHC cis rs1005277 0.563 rs2505216 chr10:38482830 T/C cg17219203 chr10:38645113 HSD17B7P2 -0.41 -5.94 -0.31 7e-9 Extrinsic epigenetic age acceleration; LIHC cis rs8016982 0.634 rs1035948 chr14:81682392 C/T cg01989461 chr14:81687754 GTF2A1 0.7 14.59 0.62 8.35e-38 Schizophrenia; LIHC cis rs4908768 0.539 rs6666191 chr1:8658442 C/T cg20416874 chr1:8611966 RERE -0.62 -11.38 -0.52 1.17e-25 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg08677398 chr8:58056175 NA 0.41 6.38 0.33 5.63e-10 Developmental language disorder (linguistic errors); LIHC cis rs7615952 0.932 rs9841157 chr3:125635655 C/A cg05084668 chr3:125655381 ALG1L -0.6 -8.51 -0.42 5.57e-16 Blood pressure (smoking interaction); LIHC cis rs4718428 0.607 rs66954441 chr7:66369209 T/C cg12165864 chr7:66369176 NA -0.46 -6.76 -0.34 5.84e-11 Corneal structure; LIHC cis rs72843506 0.656 rs73984559 chr17:19946516 C/A cg12065943 chr17:19881925 AKAP10 -0.4 -6.63 -0.34 1.32e-10 Schizophrenia; LIHC cis rs7954584 0.520 rs1169095 chr12:122465738 G/A cg13699009 chr12:122356056 WDR66 -0.41 -6.82 -0.35 4.12e-11 Mean corpuscular volume; LIHC cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg08219700 chr8:58056026 NA 0.52 6.47 0.33 3.46e-10 Developmental language disorder (linguistic errors); LIHC cis rs3823572 0.564 rs2346276 chr7:133664901 G/T cg03336402 chr7:133662267 EXOC4 -0.48 -5.74 -0.3 2.05e-8 Intelligence (multi-trait analysis); LIHC cis rs1461503 0.780 rs75981430 chr11:122842469 A/C cg14473756 chr11:122847823 NA -0.38 -6.83 -0.35 3.82e-11 Menarche (age at onset); LIHC cis rs4700695 0.764 rs152993 chr5:65262968 A/T cg21114390 chr5:65439923 SFRS12 0.44 5.72 0.3 2.31e-8 Facial morphology (factor 19); LIHC cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg13607699 chr17:42295918 UBTF 0.45 7.26 0.37 2.59e-12 Total body bone mineral density; LIHC cis rs9921222 0.542 rs9926968 chr16:381561 A/C cg00101154 chr16:420108 MRPL28 -0.56 -7.89 -0.39 4.15e-14 Bone mineral density (spine);Bone mineral density; LIHC cis rs5769765 0.542 rs5769751 chr22:50242733 T/G cg09182678 chr22:50328711 NA 0.66 6.01 0.31 4.69e-9 Schizophrenia; LIHC cis rs561341 1.000 rs8073186 chr17:30244956 T/C cg12193833 chr17:30244370 NA -0.53 -5.85 -0.3 1.16e-8 Hip circumference adjusted for BMI; LIHC cis rs629922 0.642 rs655988 chr11:114072365 A/G cg01914181 chr11:114070210 ZBTB16 0.52 7.12 0.36 6.27e-12 Paneth cell defects in Crohn's disease; LIHC cis rs780096 0.526 rs809058 chr2:27616790 T/C cg02592271 chr2:27665507 KRTCAP3 -0.45 -6.18 -0.32 1.85e-9 Total body bone mineral density; LIHC cis rs2832191 0.671 rs2832213 chr21:30512914 A/G cg08807101 chr21:30365312 RNF160 -0.42 -6.11 -0.31 2.76e-9 Dental caries; LIHC cis rs1707322 1.000 rs785498 chr1:46592414 C/T cg06784218 chr1:46089804 CCDC17 -0.38 -7.02 -0.35 1.18e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg07424592 chr7:64974309 NA 0.75 8.79 0.43 7.43e-17 Diabetic kidney disease; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg05320259 chr20:25370897 ABHD12 0.39 6.37 0.33 5.95e-10 Cognitive function; LIHC cis rs7503807 0.967 rs8064502 chr17:78562434 C/A cg09596252 chr17:78655493 RPTOR 0.38 6.55 0.33 2.07e-10 Obesity; LIHC cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.74 12.14 0.55 1.85e-28 Height; LIHC cis rs861020 0.527 rs614662 chr1:209962419 C/T cg23283495 chr1:209979779 IRF6 -0.41 -6.66 -0.34 1.09e-10 Orofacial clefts; LIHC cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg09417038 chr21:47716443 C21orf57 0.52 7.94 0.39 2.93e-14 Testicular germ cell tumor; LIHC cis rs11069349 0.608 rs9585056 chr13:100081766 A/G cg25919922 chr13:100150906 NA -0.51 -6.06 -0.31 3.56e-9 Self-reported allergy; LIHC cis rs3008870 1.000 rs58680688 chr1:67443751 C/G cg08660285 chr1:67390436 MIER1;WDR78 -0.94 -16.44 -0.66 3.58e-45 Lymphocyte percentage of white cells; LIHC cis rs11098499 0.863 rs3775858 chr4:120486028 A/G cg09307838 chr4:120376055 NA 0.74 11.27 0.52 3e-25 Corneal astigmatism; LIHC cis rs908922 0.651 rs548252 chr1:152489742 A/G cg23254163 chr1:152506842 NA -0.23 -6.13 -0.31 2.42e-9 Hair morphology; LIHC cis rs6502050 0.835 rs34960918 chr17:80113925 A/G cg11859384 chr17:80120422 CCDC57 -0.44 -5.95 -0.31 6.67e-9 Life satisfaction; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg13377154 chr12:56320780 WIBG -0.43 -6.17 -0.32 1.88e-9 Pancreatic cancer; LIHC cis rs748404 0.660 rs690512 chr15:43717678 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.74 0.39 1.1e-13 Lung cancer; LIHC cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg08499158 chr17:42289980 UBTF 0.51 8.2 0.41 4.84e-15 Total body bone mineral density; LIHC cis rs4820539 1.000 rs916583 chr22:23469267 C/T cg14186256 chr22:23484241 RTDR1 0.98 21.04 0.75 1.23e-63 Bone mineral density; LIHC cis rs7762018 0.556 rs78233989 chr6:170102041 C/G cg19338460 chr6:170058176 WDR27 -0.84 -8.83 -0.43 5.66e-17 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs57244997 0.556 rs73030428 chr6:162437606 T/C cg17173639 chr6:162384350 PARK2 -0.56 -7.39 -0.37 1.1e-12 Mosquito bite size; LIHC cis rs919433 0.713 rs11900232 chr2:198466273 T/C cg03934865 chr2:198174659 NA 0.52 7.93 0.39 3.07e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs911119 0.913 rs3810575 chr20:23583392 G/A cg16589663 chr20:23618590 CST3 0.69 7.36 0.37 1.38e-12 Chronic kidney disease; LIHC cis rs6840360 1.000 rs907237 chr4:152601146 T/G cg22705602 chr4:152727874 NA -0.28 -6.0 -0.31 4.9e-9 Intelligence (multi-trait analysis); LIHC cis rs7208859 0.673 rs9915963 chr17:29019643 C/T cg13385521 chr17:29058706 SUZ12P 0.69 7.3 0.37 2.04e-12 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs826838 1.000 rs11183160 chr12:38676702 T/C cg13010199 chr12:38710504 ALG10B 0.64 7.58 0.38 3.2e-13 Heart rate; LIHC cis rs1707322 0.752 rs28438704 chr1:46170544 G/A cg06784218 chr1:46089804 CCDC17 0.42 7.78 0.39 8.69e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11888559 0.655 rs4675309 chr2:203879503 A/G cg24605529 chr2:203879461 NBEAL1 0.73 5.94 0.31 6.86e-9 Height; LIHC cis rs1577917 0.771 rs9450319 chr6:86427325 T/G cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.39 7.29 0.37 2.14e-12 Response to antipsychotic treatment; LIHC cis rs2224391 0.704 rs9504371 chr6:5261608 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.42 -6.28 -0.32 1.02e-9 Height; LIHC cis rs2153535 0.601 rs9505451 chr6:8469950 C/T cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs11671005 0.695 rs8106061 chr19:58917990 G/C cg11952622 chr19:58962976 ZNF324B 0.7 9.11 0.44 6.98e-18 Mean platelet volume; LIHC cis rs4253772 0.591 rs6007732 chr22:46652303 A/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 6.41 0.33 4.89e-10 LDL cholesterol;Cholesterol, total; LIHC cis rs870825 0.860 rs2696044 chr4:185595988 C/G cg04058563 chr4:185651563 MLF1IP 0.71 6.42 0.33 4.67e-10 Blood protein levels; LIHC cis rs9549328 0.837 rs4907572 chr13:113647321 G/A cg08890338 chr13:113700818 MCF2L -0.36 -5.92 -0.3 8.04e-9 Systolic blood pressure; LIHC cis rs12493885 0.725 rs57740056 chr3:153744530 A/C cg10247383 chr3:153839028 SGEF 0.6 5.74 0.3 2.07e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs4478037 0.643 rs9875798 chr3:33120448 G/C cg27203090 chr3:33138513 GLB1;TMPPE -0.56 -6.92 -0.35 2.18e-11 Major depressive disorder; LIHC cis rs2204008 0.777 rs114096617 chr12:38342557 A/C cg26384229 chr12:38710491 ALG10B 0.59 8.08 0.4 1.09e-14 Bladder cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg09844907 chr16:15489619 MPV17L -0.46 -6.1 -0.31 2.8e-9 Pancreatic cancer; LIHC cis rs5753037 0.543 rs131287 chr22:30158463 C/T cg01021169 chr22:30184971 ASCC2 -0.33 -6.29 -0.32 9.81e-10 Type 1 diabetes; LIHC trans rs783540 0.656 rs783538 chr15:83253143 C/G cg18393722 chr15:85113863 UBE2QP1 -0.42 -6.59 -0.34 1.69e-10 Schizophrenia; LIHC cis rs7769051 1.000 rs5006218 chr6:133126220 T/G cg22852734 chr6:133119734 C6orf192 0.93 9.49 0.46 4.09e-19 Type 2 diabetes nephropathy; LIHC cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg06028808 chr11:68637592 NA 0.42 5.76 0.3 1.91e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs986417 0.818 rs10873125 chr14:61035024 G/A cg27398547 chr14:60952738 C14orf39 0.79 9.09 0.44 8.21e-18 Gut microbiota (bacterial taxa); LIHC cis rs12986413 1.000 rs12986413 chr19:2170954 A/T cg09261902 chr19:2140048 AP3D1 -0.36 -6.2 -0.32 1.63e-9 Height; LIHC trans rs3783890 1.000 rs10484032 chr14:93738663 A/G cg02802420 chr16:69363236 PDF;COG8 0.32 6.18 0.32 1.86e-9 Body mass index; LIHC cis rs11608355 0.545 rs2302704 chr12:109898797 A/G cg05360138 chr12:110035743 NA 0.97 11.08 0.51 1.42e-24 Neuroticism; LIHC cis rs12477438 0.765 rs7591794 chr2:99567514 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -10.32 -0.49 6.21e-22 Chronic sinus infection; LIHC cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg04267008 chr7:1944627 MAD1L1 -0.64 -10.53 -0.49 1.23e-22 Bipolar disorder and schizophrenia; LIHC cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg20607798 chr8:58055168 NA 0.49 6.07 0.31 3.33e-9 Developmental language disorder (linguistic errors); LIHC cis rs8067545 0.641 rs203466 chr17:19809953 C/G cg13482628 chr17:19912719 NA -0.39 -6.37 -0.33 6e-10 Schizophrenia; LIHC cis rs17685 0.664 rs9801113 chr7:75792031 C/T cg04592579 chr7:75616294 TMEM120A 0.41 7.0 0.35 1.33e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.65 0.38 2.07e-13 Prudent dietary pattern; LIHC cis rs748404 0.697 rs493444 chr15:43566470 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.45 7.55 0.38 3.96e-13 Lung cancer; LIHC cis rs4927850 1.000 rs10881564 chr3:195750326 C/T cg01181863 chr3:195395398 SDHAP2 -0.54 -7.12 -0.36 6.4e-12 Pancreatic cancer; LIHC cis rs3768617 0.528 rs2027082 chr1:183084608 C/A ch.1.3577855R chr1:183094577 LAMC1 0.6 10.54 0.5 1.12e-22 Fuchs's corneal dystrophy; LIHC cis rs9324022 0.929 rs72698718 chr14:101178555 G/A cg18089426 chr14:101175970 NA 0.48 6.0 0.31 5.14e-9 Plateletcrit; LIHC cis rs7116495 0.609 rs3750907 chr11:71822560 T/C cg10381502 chr11:71823885 C11orf51 1.06 8.91 0.43 3.06e-17 Severe influenza A (H1N1) infection; LIHC cis rs992157 0.644 rs6741757 chr2:219182748 T/C cg20019365 chr2:219134978 PNKD;AAMP 0.71 10.05 0.48 5.54e-21 Colorectal cancer; LIHC cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg00684032 chr4:1343700 KIAA1530 0.39 6.67 0.34 1.04e-10 Obesity-related traits; LIHC cis rs1077514 0.515 rs1767141 chr1:23734350 G/T cg19827787 chr1:23763612 ASAP3 -0.31 -5.81 -0.3 1.4e-8 Cholesterol, total; LIHC cis rs2153535 0.580 rs1414342 chr6:8462552 A/G cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.95e-15 Motion sickness; LIHC cis rs7078219 0.543 rs10786557 chr10:101283328 C/G cg06854084 chr10:101292507 NKX2-3 -0.33 -6.06 -0.31 3.5e-9 Dental caries; LIHC cis rs2274273 0.870 rs8023197 chr14:55767395 G/T cg01864836 chr14:55583639 NA -0.4 -7.45 -0.37 7.51e-13 Protein biomarker; LIHC cis rs7107174 0.901 rs10899494 chr11:78122208 G/T cg02023728 chr11:77925099 USP35 0.4 7.36 0.37 1.42e-12 Testicular germ cell tumor; LIHC cis rs7572733 0.534 rs700662 chr2:198668751 T/C cg00792783 chr2:198669748 PLCL1 0.46 6.79 0.34 5.01e-11 Dermatomyositis; LIHC cis rs9814567 0.964 rs9820150 chr3:134223011 C/G cg06541857 chr3:134203789 ANAPC13;CEP63 -0.39 -5.76 -0.3 1.88e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg18230493 chr5:56204884 C5orf35 -0.46 -6.4 -0.33 5.13e-10 Initial pursuit acceleration; LIHC cis rs11676348 1.000 rs11676348 chr2:219010146 C/T cg00012203 chr2:219082015 ARPC2 -0.52 -7.17 -0.36 4.55e-12 Ulcerative colitis; LIHC cis rs10751667 0.666 rs7943140 chr11:973824 T/C cg06064525 chr11:970664 AP2A2 -0.56 -14.83 -0.63 8.92e-39 Alzheimer's disease (late onset); LIHC cis rs59698941 0.709 rs12163973 chr5:132226664 G/A cg02081065 chr5:132209139 LEAP2 0.26 5.78 0.3 1.67e-8 Apolipoprotein A-IV levels; LIHC cis rs3806843 0.966 rs3806844 chr5:140206263 A/T cg26395211 chr5:140044315 WDR55 -0.44 -6.59 -0.34 1.65e-10 Depressive symptoms (multi-trait analysis); LIHC cis rs9393692 0.905 rs6940237 chr6:26282322 T/C cg00631329 chr6:26305371 NA -0.42 -7.18 -0.36 4.3e-12 Educational attainment; LIHC cis rs2075371 1.000 rs8134 chr7:133974519 A/G cg11752832 chr7:134001865 SLC35B4 0.48 7.31 0.37 1.86e-12 Mean platelet volume; LIHC cis rs703842 1.000 rs2069502 chr12:58144665 A/G cg18357645 chr12:58087776 OS9 0.45 6.65 0.34 1.19e-10 Multiple sclerosis; LIHC cis rs1506636 1.000 rs10225428 chr7:123357646 A/G cg03229431 chr7:123269106 ASB15 -0.59 -11.95 -0.54 9.29e-28 Plateletcrit;Platelet count; LIHC cis rs7762018 0.655 rs11966349 chr6:170162537 A/G cg19338460 chr6:170058176 WDR27 0.4 6.39 0.33 5.37e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC cis rs3540 0.554 rs34650360 chr15:91059017 T/C cg22089800 chr15:90895588 ZNF774 -0.54 -7.64 -0.38 2.2e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs12744310 1.000 rs2364535 chr1:41766236 C/T cg03962019 chr1:41807865 NA 0.36 5.9 0.3 8.85e-9 Cognitive ability (multi-trait analysis);Intelligence;Cognitive ability; LIHC cis rs11098499 0.754 rs10213554 chr4:120260785 A/G cg09307838 chr4:120376055 NA -0.71 -11.33 -0.52 1.69e-25 Corneal astigmatism; LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg20102877 chr2:27665638 KRTCAP3 -0.44 -6.07 -0.31 3.39e-9 Total body bone mineral density; LIHC cis rs4234798 1.000 rs4689653 chr4:7223319 T/G cg13439315 chr4:7197511 SORCS2 -0.34 -5.75 -0.3 2.01e-8 Insulin-like growth factors; LIHC cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs4595586 0.525 rs34204378 chr12:39425759 C/T cg26384229 chr12:38710491 ALG10B 0.5 6.0 0.31 4.92e-9 Morning vs. evening chronotype; LIHC cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 10.0 0.48 8.11e-21 Platelet count; LIHC cis rs35306767 0.903 rs11253467 chr10:901244 A/G cg26597838 chr10:835615 NA 1.13 13.37 0.59 4.36e-33 Eosinophil percentage of granulocytes; LIHC cis rs79149102 0.579 rs12593542 chr15:75282147 C/G cg15902774 chr15:75289873 SCAMP5 0.37 5.76 0.3 1.84e-8 Lung cancer; LIHC cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg16034541 chr3:195490309 MUC4 -0.61 -9.56 -0.46 2.43e-19 Lung disease severity in cystic fibrosis; LIHC trans rs1814175 0.781 rs28681334 chr11:50051177 C/T cg15704280 chr7:45808275 SEPT13 -1.0 -23.71 -0.79 3.38e-74 Height; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg09400194 chr10:81107848 PPIF 0.39 6.3 0.32 9.1e-10 Cognitive function; LIHC cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg25894440 chr7:65020034 NA 0.51 6.12 0.31 2.63e-9 Diabetic kidney disease; LIHC cis rs10949834 0.642 rs2356530 chr7:73533221 T/A cg07137043 chr7:73588983 EIF4H -0.6 -6.01 -0.31 4.74e-9 Verbal memory performance (residualized delayed recall change); LIHC cis rs950169 0.887 rs35986397 chr15:84955107 G/A cg03959625 chr15:84868606 LOC388152 0.48 6.78 0.34 5.21e-11 Schizophrenia; LIHC cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg13409248 chr3:40428643 ENTPD3 0.5 8.53 0.42 4.92e-16 Renal cell carcinoma; LIHC cis rs11252926 0.537 rs4881274 chr10:459940 G/A cg16346588 chr10:242978 ZMYND11 0.4 6.18 0.32 1.82e-9 Psychosis in Alzheimer's disease; LIHC cis rs8084351 0.539 rs9949949 chr18:50571241 A/G cg24270629 chr18:50823537 DCC 0.41 6.35 0.32 6.78e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs3096299 0.559 rs9931073 chr16:89568513 G/C cg02034447 chr16:89574710 SPG7 0.38 5.77 0.3 1.76e-8 Multiple myeloma (IgH translocation); LIHC cis rs2978263 0.566 rs17625964 chr8:30287906 C/T cg05780722 chr8:30327988 RBPMS 0.33 6.14 0.31 2.35e-9 Cognitive performance; LIHC cis rs6582630 0.555 rs7978749 chr12:38527141 G/T cg26384229 chr12:38710491 ALG10B 0.68 9.62 0.46 1.53e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs12960505 0.506 rs4940259 chr18:50997336 A/T cg24270629 chr18:50823537 DCC 0.47 6.65 0.34 1.15e-10 Intelligence (multi-trait analysis); LIHC cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg05564831 chr3:52568323 NT5DC2 -0.38 -6.17 -0.32 1.88e-9 Bipolar disorder; LIHC cis rs6967414 0.681 rs11979878 chr7:6753803 A/G cg00387323 chr7:6746715 ZNF12 0.64 7.05 0.36 1e-11 Hematocrit;Hemoglobin concentration; LIHC cis rs2050392 0.792 rs9338188 chr10:30721963 G/C cg25182066 chr10:30743637 MAP3K8 -0.48 -7.93 -0.39 3.08e-14 Inflammatory bowel disease; LIHC cis rs4819052 0.851 rs8127834 chr21:46696109 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 8.19 0.41 5.11e-15 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs2243480 1.000 rs4149468 chr7:65825690 T/C cg10756647 chr7:56101905 PSPH 1.03 12.51 0.56 7.74e-30 Diabetic kidney disease; LIHC cis rs9911578 0.967 rs302843 chr17:56727986 C/T cg12560992 chr17:57184187 TRIM37 0.98 17.75 0.69 1.91e-50 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.4 5.8 0.3 1.54e-8 Menopause (age at onset); LIHC cis rs13096357 0.520 rs17080319 chr3:48732480 T/C cg07636037 chr3:49044803 WDR6 -0.73 -7.78 -0.39 8.38e-14 Cognitive ability (multi-trait analysis); LIHC trans rs7613875 0.521 rs4688754 chr3:50074641 G/T cg21659725 chr3:3221576 CRBN -0.54 -8.06 -0.4 1.25e-14 Body mass index; LIHC cis rs2066819 1.000 rs77120931 chr12:56646213 A/C cg26734620 chr12:56694298 CS 1.21 10.41 0.49 3.22e-22 Psoriasis vulgaris; LIHC trans rs61931739 0.517 rs12815556 chr12:34319670 G/A cg26384229 chr12:38710491 ALG10B 0.57 7.4 0.37 1.07e-12 Morning vs. evening chronotype; LIHC cis rs763121 0.853 rs5750662 chr22:39072472 G/A cg06022373 chr22:39101656 GTPBP1 0.65 11.42 0.53 8.21e-26 Menopause (age at onset); LIHC cis rs9378688 0.546 rs2505673 chr6:2356229 A/G cg12303981 chr6:2244766 GMDS -0.45 -6.46 -0.33 3.64e-10 Caudate nucleus volume; LIHC cis rs2576037 0.526 rs2257027 chr18:44566990 A/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.69 -11.05 -0.51 1.76e-24 Personality dimensions; LIHC cis rs2073300 1.000 rs6137966 chr20:23444359 A/T cg16736954 chr20:23401023 NAPB 0.54 5.98 0.31 5.58e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs4728302 0.869 rs2042455 chr7:133580545 A/G cg10665199 chr7:133106180 EXOC4 0.37 6.47 0.33 3.42e-10 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs11630290 0.592 rs12232261 chr15:64153302 A/G cg12036633 chr15:63758958 NA 0.63 6.7 0.34 8.73e-11 Iris characteristics; LIHC cis rs743757 1.000 rs743757 chr3:50476378 C/G cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.5 -7.87 -0.39 4.68e-14 Diastolic blood pressure; LIHC cis rs9911578 0.933 rs2531726 chr17:56522533 C/T cg05425664 chr17:57184151 TRIM37 0.57 8.5 0.42 5.77e-16 Intelligence (multi-trait analysis); LIHC cis rs262150 1.000 rs262149 chr7:158778256 A/G cg19418458 chr7:158789849 NA 0.4 6.92 0.35 2.25e-11 Facial morphology (factor 20); LIHC cis rs748404 0.697 rs555001 chr15:43545728 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.49 8.56 0.42 3.93e-16 Lung cancer; LIHC cis rs35146811 0.844 rs4729576 chr7:99692594 G/A cg13334819 chr7:99746414 C7orf59 -0.6 -8.51 -0.42 5.58e-16 Coronary artery disease; LIHC cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg00343986 chr7:65444356 GUSB 0.44 6.24 0.32 1.29e-9 Calcium levels; LIHC cis rs7296418 0.816 rs1790096 chr12:123710364 C/T cg05973401 chr12:123451056 ABCB9 0.44 6.39 0.33 5.28e-10 Platelet count; LIHC cis rs11676348 0.805 rs12694428 chr2:218958820 G/A cg00012203 chr2:219082015 ARPC2 -0.46 -5.97 -0.31 6.05e-9 Ulcerative colitis; LIHC cis rs2204008 0.744 rs11514071 chr12:38392076 C/T cg26384229 chr12:38710491 ALG10B 0.58 7.83 0.39 6.15e-14 Bladder cancer; LIHC cis rs2073499 0.872 rs2282751 chr3:50291785 A/G cg09545109 chr3:50388910 TUSC4;CYB561D2 -0.92 -15.34 -0.64 8.76e-41 Schizophrenia; LIHC cis rs757110 0.740 rs10832776 chr11:17385224 C/A cg15432903 chr11:17409602 KCNJ11 0.65 10.12 0.48 3.11e-21 Type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg15921271 chr3:23957976 RPL15;NKIRAS1 -0.46 -6.47 -0.33 3.4e-10 Pancreatic cancer; LIHC cis rs798766 1.000 rs4865467 chr4:1745500 G/T cg21231739 chr4:1642635 FAM53A 0.38 6.05 0.31 3.81e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs9549328 0.731 rs7983602 chr13:113620482 A/G cg18289306 chr13:113640169 MCF2L 0.42 6.31 0.32 8.85e-10 Systolic blood pressure; LIHC trans rs561341 1.000 rs693116 chr17:30246124 C/T cg20587970 chr11:113659929 NA -1.47 -11.82 -0.54 2.81e-27 Hip circumference adjusted for BMI; LIHC cis rs6951245 0.554 rs76243429 chr7:1152543 C/T cg04025307 chr7:1156635 C7orf50 0.63 6.29 0.32 9.75e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs1005277 0.579 rs1740742 chr10:38518860 C/T cg27523141 chr10:43048294 ZNF37B 0.39 6.56 0.33 1.95e-10 Extrinsic epigenetic age acceleration; LIHC cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg22800045 chr5:56110881 MAP3K1 0.68 8.72 0.43 1.2e-16 Initial pursuit acceleration; LIHC cis rs908922 0.887 rs6587688 chr1:152529622 C/T cg20991723 chr1:152506922 NA -0.39 -6.2 -0.32 1.59e-9 Hair morphology; LIHC cis rs875971 0.862 rs4718377 chr7:66049678 C/T cg11764359 chr7:65958608 NA -0.78 -13.77 -0.6 1.22e-34 Aortic root size; LIHC cis rs2153535 0.580 rs2184583 chr6:8447808 A/G cg21535247 chr6:8435926 SLC35B3 0.61 8.05 0.4 1.36e-14 Motion sickness; LIHC cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg25894440 chr7:65020034 NA 0.54 6.28 0.32 1.05e-9 Diabetic kidney disease; LIHC trans rs8117834 0.574 rs6118060 chr20:8087337 C/T cg00593689 chr4:53575888 NA 0.41 6.84 0.35 3.77e-11 Chronic kidney disease; LIHC cis rs9811920 0.609 rs9872871 chr3:99658702 C/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.8 -0.3 1.48e-8 Axial length; LIHC cis rs208515 0.556 rs12214562 chr6:66681011 T/A cg07460842 chr6:66804631 NA 0.76 8.75 0.43 1e-16 Exhaled nitric oxide levels; LIHC cis rs1448094 0.512 rs6539927 chr12:86244486 T/C cg02569458 chr12:86230093 RASSF9 0.47 6.36 0.33 6.47e-10 Major depressive disorder; LIHC cis rs10463316 0.855 rs352701 chr5:150736474 A/G cg03212797 chr5:150827313 SLC36A1 -0.48 -7.15 -0.36 5.31e-12 Metabolite levels (Pyroglutamine); LIHC trans rs17685 0.672 rs10952841 chr7:75778626 A/C cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7945705 0.875 rs4929914 chr11:8824388 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.37 -6.19 -0.32 1.71e-9 Hemoglobin concentration; LIHC cis rs17739167 0.550 rs11070354 chr15:42233211 C/T cg20935245 chr15:42234343 EHD4 0.4 7.51 0.38 5.17e-13 Monocyte count; LIHC cis rs6500602 0.647 rs4785967 chr16:4523208 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 6.2 0.32 1.65e-9 Schizophrenia; LIHC cis rs2153535 0.580 rs9393016 chr6:8458573 T/A cg21535247 chr6:8435926 SLC35B3 0.65 8.57 0.42 3.57e-16 Motion sickness; LIHC cis rs7940866 0.804 rs3910266 chr11:130814272 A/C cg12179176 chr11:130786555 SNX19 0.64 9.41 0.45 7.25e-19 Schizophrenia; LIHC trans rs783540 1.000 rs11631963 chr15:83318202 T/C cg18393722 chr15:85113863 UBE2QP1 0.38 6.65 0.34 1.17e-10 Schizophrenia; LIHC cis rs7914558 0.966 rs11191518 chr10:104782853 C/G cg15744005 chr10:104629667 AS3MT -0.39 -8.75 -0.43 9.67e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC trans rs61931739 0.534 rs12372721 chr12:34175301 C/T cg26384229 chr12:38710491 ALG10B 0.59 7.5 0.38 5.55e-13 Morning vs. evening chronotype; LIHC cis rs4819052 0.851 rs8133045 chr21:46658137 A/G cg22633049 chr21:46681294 NA -0.37 -6.33 -0.32 7.69e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6430585 0.528 rs309162 chr2:136690783 T/A cg15123519 chr2:136567270 LCT -0.35 -5.73 -0.3 2.16e-8 Corneal structure; LIHC cis rs10256972 1.000 rs10256972 chr7:1039003 G/T cg04025307 chr7:1156635 C7orf50 -0.48 -8.13 -0.4 8.16e-15 Longevity;Endometriosis; LIHC cis rs3540 0.512 rs3862437 chr15:91084632 A/G cg22089800 chr15:90895588 ZNF774 -0.53 -7.55 -0.38 3.9e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs2075371 1.000 rs2075373 chr7:133984683 A/C cg20476274 chr7:133979776 SLC35B4 0.75 12.53 0.56 6.44e-30 Mean platelet volume; LIHC cis rs67311347 1.000 rs34762643 chr3:40475433 C/T cg00656387 chr3:40428638 ENTPD3 0.42 7.02 0.35 1.21e-11 Renal cell carcinoma; LIHC trans rs57221529 0.664 rs72704802 chr5:554211 C/T cg25482853 chr8:67687455 SGK3 0.68 6.54 0.33 2.29e-10 Lung disease severity in cystic fibrosis; LIHC trans rs10842750 1.000 rs10842750 chr12:26690565 G/T cg01402409 chr4:78978133 FRAS1 -0.49 -6.87 -0.35 2.97e-11 Kashin-Beck disease; LIHC cis rs1559088 0.649 rs4528686 chr19:33556074 A/G cg17764715 chr19:33622953 WDR88 0.41 5.79 0.3 1.61e-8 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs7618501 0.521 rs3796386 chr3:49899795 G/A cg24110177 chr3:50126178 RBM5 -0.54 -8.42 -0.41 1.03e-15 Intelligence (multi-trait analysis); LIHC cis rs992157 1.000 rs992157 chr2:219154781 A/G cg00012203 chr2:219082015 ARPC2 -0.83 -13.3 -0.58 7.8e-33 Colorectal cancer; LIHC cis rs2963155 0.518 rs853177 chr5:142635460 A/G cg17617527 chr5:142782415 NR3C1 0.82 9.13 0.44 6.29e-18 Breast cancer; LIHC cis rs11608355 0.515 rs12831026 chr12:109903651 C/T cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs9309473 0.718 rs10175529 chr2:73606093 A/G cg20560298 chr2:73613845 ALMS1 -0.47 -7.53 -0.38 4.65e-13 Metabolite levels; LIHC cis rs2797160 0.967 rs2797162 chr6:126011381 G/T cg05901451 chr6:126070800 HEY2 0.45 7.45 0.37 7.66e-13 Endometrial cancer; LIHC cis rs1163251 0.837 rs611365 chr1:120242571 C/T cg19096424 chr1:120255104 PHGDH 0.63 8.1 0.4 9.82e-15 Blood metabolite levels; LIHC trans rs6912958 0.712 rs4707383 chr6:88330602 T/A cg23605328 chr1:201951606 RNPEP 0.39 6.17 0.32 1.9e-9 Monocyte percentage of white cells; LIHC cis rs561341 0.609 rs7214626 chr17:30190989 G/A cg13647721 chr17:30228624 UTP6 -0.7 -7.16 -0.36 4.85e-12 Hip circumference adjusted for BMI; LIHC cis rs9355610 0.609 rs62436424 chr6:167374258 A/G cg23791538 chr6:167370224 RNASET2 0.58 9.13 0.44 6.31e-18 Graves' disease; LIHC cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.7 0.38 1.5e-13 Prudent dietary pattern; LIHC cis rs2839186 0.739 rs7282763 chr21:47696800 C/T cg12016809 chr21:47604291 C21orf56 0.42 6.07 0.31 3.37e-9 Testicular germ cell tumor; LIHC cis rs3808502 0.527 rs2736374 chr8:11113828 A/G cg14025978 chr8:10786150 XKR6 0.47 5.73 0.3 2.25e-8 Neuroticism; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg11702503 chr19:6215254 MLLT1 0.43 6.34 0.32 7.13e-10 Bilirubin levels; LIHC cis rs2153535 0.580 rs6900007 chr6:8474035 C/T cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs6424115 0.830 rs3003333 chr1:24194014 A/T cg10978503 chr1:24200527 CNR2 -0.35 -8.29 -0.41 2.56e-15 Immature fraction of reticulocytes; LIHC cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.54 -7.86 -0.39 5.1e-14 Prostate cancer; LIHC cis rs7408868 1.000 rs8107180 chr19:15275430 T/C cg09752223 chr19:15281200 NOTCH3 -0.37 -5.89 -0.3 9.39e-9 Pulse pressure; LIHC cis rs28374715 0.787 rs11856169 chr15:41547938 C/T cg18705301 chr15:41695430 NDUFAF1 -0.93 -10.82 -0.5 1.17e-23 Ulcerative colitis; LIHC cis rs11153147 0.649 rs11153145 chr6:109300799 C/T cg05315195 chr6:109294784 ARMC2 -0.53 -5.88 -0.3 9.87e-9 Mean corpuscular volume; LIHC cis rs7116495 0.867 rs612255 chr11:71778664 A/G cg10381502 chr11:71823885 C11orf51 -1.06 -8.91 -0.43 3.07e-17 Severe influenza A (H1N1) infection; LIHC cis rs13118159 0.651 rs4974599 chr4:1314430 A/C cg19318889 chr4:1322082 MAEA 0.55 8.83 0.43 5.56e-17 Longevity; LIHC trans rs60843830 1.000 rs36216559 chr2:262335 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.68 9.68 0.46 9.53e-20 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs780096 0.526 rs12476704 chr2:27613031 C/A cg11618577 chr2:27665543 KRTCAP3 -0.43 -6.01 -0.31 4.75e-9 Total body bone mineral density; LIHC cis rs36051895 0.559 rs1590268 chr9:5209433 T/A cg02405213 chr9:5042618 JAK2 -0.61 -10.32 -0.49 6.24e-22 Pediatric autoimmune diseases; LIHC cis rs1003719 0.715 rs35199609 chr21:38510262 T/C cg10648535 chr21:38446584 PIGP;TTC3 -0.74 -11.25 -0.52 3.45e-25 Eye color traits; LIHC cis rs727563 0.593 rs5758461 chr22:42162189 G/C cg06634786 chr22:41940651 POLR3H 0.73 7.39 0.37 1.15e-12 Crohn's disease;Inflammatory bowel disease; LIHC cis rs4728302 0.583 rs12707091 chr7:133185749 A/G cg10665199 chr7:133106180 EXOC4 0.52 8.49 0.42 6.55e-16 Intelligence;Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs12220238 1.000 rs10824125 chr10:75997498 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.63 6.25 0.32 1.24e-9 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs801193 0.660 rs1016265 chr7:66214567 C/T cg11764359 chr7:65958608 NA 0.82 14.53 0.62 1.33e-37 Aortic root size; LIHC cis rs780096 0.526 rs780106 chr2:27681598 A/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.69 -0.34 9.38e-11 Total body bone mineral density; LIHC cis rs116095464 0.558 rs2288457 chr5:231270 C/T cg22857025 chr5:266934 NA -1.48 -18.2 -0.7 3.22e-52 Breast cancer; LIHC cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg13409248 chr3:40428643 ENTPD3 0.49 8.22 0.41 4.34e-15 Renal cell carcinoma; LIHC cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg27572855 chr1:25598939 RHD 0.39 8.48 0.42 6.95e-16 Erythrocyte sedimentation rate; LIHC cis rs9868809 0.656 rs13324119 chr3:48710606 G/C cg07636037 chr3:49044803 WDR6 -0.62 -6.98 -0.35 1.5e-11 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 -0.77 -7.75 -0.39 1.03e-13 Platelet count; LIHC cis rs10791097 0.547 rs12365680 chr11:130749059 C/T cg12179176 chr11:130786555 SNX19 0.81 13.25 0.58 1.21e-32 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs651907 0.557 rs13077925 chr3:101488181 T/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.43 -5.96 -0.31 6.42e-9 Colorectal cancer; LIHC trans rs6934970 0.932 rs62416967 chr6:113011386 A/G cg09308777 chr6:169852575 NA 0.6 6.21 0.32 1.5e-9 Bipolar disorder (body mass index interaction); LIHC cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg11663144 chr21:46675770 NA -0.34 -6.31 -0.32 8.46e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9388451 0.626 rs7748729 chr6:126077381 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.66 -11.04 -0.51 1.9e-24 Brugada syndrome; LIHC cis rs780096 0.565 rs780104 chr2:27677691 G/A cg27432699 chr2:27873401 GPN1 -0.5 -7.19 -0.36 4.23e-12 Total body bone mineral density; LIHC cis rs6701037 0.681 rs2285220 chr1:175130773 T/A cg00321850 chr1:175162397 KIAA0040 -0.43 -6.89 -0.35 2.62e-11 Alcohol dependence; LIHC cis rs7124681 0.584 rs11039448 chr11:47918416 G/T cg20307385 chr11:47447363 PSMC3 -0.68 -10.14 -0.48 2.71e-21 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; LIHC trans rs61931739 0.534 rs1817761 chr12:34105719 C/T cg26384229 chr12:38710491 ALG10B 0.53 7.29 0.37 2.14e-12 Morning vs. evening chronotype; LIHC cis rs13217239 0.646 rs12527111 chr6:27006475 C/T cg12292205 chr6:26970375 C6orf41 0.44 7.64 0.38 2.25e-13 Schizophrenia; LIHC cis rs4808199 0.895 rs8105094 chr19:19374061 C/T cg03709012 chr19:19516395 GATAD2A 0.97 14.67 0.62 4.02e-38 Nonalcoholic fatty liver disease; LIHC cis rs7107174 1.000 rs2510048 chr11:77987464 T/C cg02023728 chr11:77925099 USP35 0.49 9.34 0.45 1.23e-18 Testicular germ cell tumor; LIHC trans rs2726453 0.562 rs2713834 chr4:106310520 G/T cg05152925 chr14:45603667 FKBP3;FANCM -0.46 -6.21 -0.32 1.56e-9 Intelligence (multi-trait analysis); LIHC cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg11644478 chr21:40555479 PSMG1 0.81 9.94 0.47 1.29e-20 Cognitive function; LIHC trans rs12599106 0.707 rs2163977 chr16:34916134 A/G cg26668828 chr6:292823 DUSP22 -0.61 -8.31 -0.41 2.33e-15 Menopause (age at onset); LIHC cis rs11758351 0.660 rs113208674 chr6:26210465 C/G cg03854865 chr6:26224070 HIST1H3E 0.59 6.43 0.33 4.36e-10 Gout;Renal underexcretion gout; LIHC cis rs7617773 0.817 rs6794644 chr3:48330037 T/C cg11946769 chr3:48343235 NME6 0.87 11.29 0.52 2.49e-25 Coronary artery disease; LIHC trans rs1814175 0.817 rs28525029 chr11:50045815 A/G cg15704280 chr7:45808275 SEPT13 -1.0 -23.24 -0.78 2.34e-72 Height; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00570391 chr7:815417 HEATR2 -0.43 -6.48 -0.33 3.29e-10 Lobe attachment (rater-scored or self-reported); LIHC trans rs2847476 0.690 rs7929497 chr11:114192132 C/G cg18786224 chr11:69830436 NA 0.34 6.59 0.34 1.66e-10 Volumetric brain MRI; LIHC cis rs933688 1.000 rs332529 chr5:90789470 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 0.84 14.73 0.62 2.24e-38 Smoking behavior; LIHC cis rs7552404 0.883 rs7513363 chr1:76143443 A/G cg22875332 chr1:76189707 ACADM 0.47 7.37 0.37 1.27e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg23262073 chr20:60523788 NA -0.37 -7.45 -0.37 7.54e-13 Obesity-related traits; LIHC cis rs9733 0.519 rs7521898 chr1:150707596 G/A cg15448220 chr1:150897856 SETDB1 0.43 6.77 0.34 5.77e-11 Tonsillectomy; LIHC trans rs923375 1.000 rs923375 chr17:3393068 C/T cg19461880 chr11:6504366 FXC1 -0.37 -6.17 -0.32 1.94e-9 Myopia (pathological); LIHC cis rs7107174 0.892 rs1567891 chr11:78101985 A/G cg02023728 chr11:77925099 USP35 0.46 8.57 0.42 3.54e-16 Testicular germ cell tumor; LIHC cis rs11724804 0.532 rs7657611 chr4:880558 G/C cg08222618 chr4:941054 TMEM175 0.57 8.3 0.41 2.49e-15 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs9486719 0.948 rs11152953 chr6:96894305 C/T cg06623918 chr6:96969491 KIAA0776 -0.72 -7.21 -0.36 3.57e-12 Migraine;Coronary artery disease; LIHC cis rs6545883 0.894 rs2600660 chr2:61549600 G/T cg15711740 chr2:61764176 XPO1 0.42 5.77 0.3 1.8e-8 Tuberculosis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg24106943 chr1:165738203 TMCO1 -0.47 -6.7 -0.34 8.78e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg23565663 chr8:10621935 NA -0.48 -7.26 -0.37 2.71e-12 Lobe attachment (rater-scored or self-reported); LIHC cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg04267008 chr7:1944627 MAD1L1 -0.64 -10.15 -0.48 2.46e-21 Bipolar disorder and schizophrenia; LIHC cis rs12980942 0.591 rs2304232 chr19:41762525 A/G cg25627403 chr19:41769009 HNRNPUL1 0.6 7.23 0.36 3.28e-12 Coronary artery disease; LIHC cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg21724239 chr8:58056113 NA 0.45 6.08 0.31 3.23e-9 Developmental language disorder (linguistic errors); LIHC cis rs11718455 0.920 rs13084408 chr3:44008967 G/A cg08738300 chr3:44038990 NA 0.51 8.81 0.43 6.45e-17 Coronary artery disease; LIHC cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg12310025 chr6:25882481 NA 0.55 7.78 0.39 8.81e-14 Blood metabolite levels; LIHC cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg00280220 chr17:61926910 NA 0.42 6.76 0.34 5.8200000000000003e-11 Prudent dietary pattern; LIHC cis rs7618501 0.574 rs6765484 chr3:50041313 C/T cg21467203 chr3:49911342 NA 0.43 7.71 0.38 1.37e-13 Intelligence (multi-trait analysis); LIHC cis rs2070488 0.813 rs3749387 chr3:38496193 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 15.1 0.63 7.61e-40 Electrocardiographic conduction measures; LIHC cis rs2274273 0.529 rs10131562 chr14:55847015 G/A cg01864836 chr14:55583639 NA -0.34 -5.78 -0.3 1.64e-8 Protein biomarker; LIHC trans rs6847067 0.800 rs11097026 chr4:85803607 G/T cg02712183 chr4:82388742 RASGEF1B -0.3 -6.07 -0.31 3.43e-9 Oropharynx cancer; LIHC cis rs875971 0.789 rs7808013 chr7:66071196 A/G cg18252515 chr7:66147081 NA 0.45 6.56 0.33 1.97e-10 Aortic root size; LIHC cis rs4908768 0.859 rs55802878 chr1:8666411 T/C cg25722041 chr1:8623473 RERE 0.43 5.78 0.3 1.7e-8 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2302190 0.882 rs11656888 chr17:56546725 T/A cg12560992 chr17:57184187 TRIM37 0.73 9.14 0.44 5.78e-18 Vitamin D levels; LIHC cis rs17608059 0.566 rs5005684 chr17:13910633 T/C cg27005118 chr17:13972210 COX10 -0.35 -6.49 -0.33 3.02e-10 Temperament; LIHC trans rs877282 0.853 rs7092805 chr10:756246 G/A cg22713356 chr15:30763199 NA 1.39 11.96 0.54 8.81e-28 Uric acid levels; LIHC cis rs58688157 0.921 rs12805435 chr11:612355 T/C cg16486109 chr11:613632 IRF7 0.61 6.81 0.35 4.44e-11 Systemic lupus erythematosus; LIHC trans rs2727020 0.729 rs588458 chr11:49214048 C/A cg03929089 chr4:120376271 NA 0.78 13.82 0.6 8.23e-35 Coronary artery disease; LIHC cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 11.17 0.52 6.69e-25 Colorectal cancer; LIHC cis rs35883536 1.000 rs1832123 chr1:101168196 A/G cg14515779 chr1:101123966 NA -0.7 -13.9 -0.6 3.84e-35 Monocyte count; LIHC cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg07414643 chr4:187882934 NA 0.23 5.94 0.31 7.01e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs6964587 1.000 rs10274756 chr7:91740796 G/A cg17063962 chr7:91808500 NA 1.01 19.34 0.72 8.03e-57 Breast cancer; LIHC cis rs6450176 0.909 rs1541681 chr5:53304620 G/T ch.5.1024479R chr5:53302184 ARL15 -0.81 -14.48 -0.62 2.23e-37 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs11233413 0.957 rs1943341 chr11:82766826 T/C cg24227371 chr11:82718527 RAB30 -0.35 -7.48 -0.37 6.36e-13 Economic and political preferences (feminism/equality); LIHC cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg05564831 chr3:52568323 NT5DC2 0.36 5.9 0.3 8.7e-9 Electroencephalogram traits; LIHC cis rs6788895 1.000 rs79709238 chr3:150488477 A/C cg09723797 chr3:150481914 SIAH2 0.81 10.99 0.51 3e-24 Breast cancer; LIHC cis rs4689592 0.503 rs66885632 chr4:7053738 T/C cg19539972 chr4:7069911 GRPEL1 -0.7 -9.74 -0.47 6.13e-20 Monocyte percentage of white cells; LIHC cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg05590025 chr7:65112418 INTS4L2 0.6 6.62 0.34 1.38e-10 Diabetic kidney disease; LIHC cis rs798554 1.000 rs798562 chr7:2757938 C/T cg13628971 chr7:2884303 GNA12 0.48 6.83 0.35 3.79e-11 Height; LIHC cis rs3540 0.512 rs17263706 chr15:91078803 G/T cg22089800 chr15:90895588 ZNF774 0.54 7.56 0.38 3.74e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs10751667 0.643 rs10794350 chr11:946070 A/G cg10932868 chr11:921992 NA 0.38 7.28 0.37 2.31e-12 Alzheimer's disease (late onset); LIHC cis rs1348850 0.645 rs11887886 chr2:178425730 C/T cg27490568 chr2:178487706 NA 0.8 9.72 0.47 7.26e-20 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs9303401 0.659 rs12948133 chr17:56673602 T/C cg25039879 chr17:56429692 SUPT4H1 0.79 8.97 0.44 1.98e-17 Cognitive test performance; LIHC cis rs2075371 0.897 rs1643102 chr7:133999983 T/A cg11752832 chr7:134001865 SLC35B4 0.52 7.65 0.38 2.01e-13 Mean platelet volume; LIHC cis rs116095464 0.558 rs60251075 chr5:245292 T/C cg22496380 chr5:211416 CCDC127 -1.03 -10.7 -0.5 3.15e-23 Breast cancer; LIHC cis rs4820294 0.669 rs7287340 chr22:38054325 C/T cg00142150 chr22:38071001 LGALS1 0.44 7.48 0.38 6.14e-13 Fat distribution (HIV); LIHC cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs4555082 0.957 rs10140586 chr14:105749582 A/G cg10792982 chr14:105748885 BRF1 0.42 5.75 0.3 1.99e-8 Mean platelet volume;Platelet distribution width; LIHC cis rs483180 0.511 rs496195 chr1:120207182 A/G cg19096424 chr1:120255104 PHGDH -0.59 -7.4 -0.37 1.07e-12 Macular telangiectasia type 2; LIHC cis rs13256369 0.901 rs12681298 chr8:8566235 A/G cg00074818 chr8:8560427 CLDN23 -0.4 -6.75 -0.34 6.32e-11 Obesity-related traits; LIHC cis rs16958440 0.581 rs60726022 chr18:44679813 A/G cg17192377 chr18:44677553 HDHD2 0.71 7.78 0.39 8.44e-14 Sitting height ratio; LIHC cis rs644799 0.965 rs573758 chr11:95539591 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 17.19 0.68 3.68e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs116095464 0.558 rs6878061 chr5:223072 A/G cg22857025 chr5:266934 NA -1.53 -18.47 -0.71 2.44e-53 Breast cancer; LIHC cis rs4423214 0.650 rs4245442 chr11:71220909 T/C cg05163923 chr11:71159392 DHCR7 0.72 10.59 0.5 7.34e-23 Vitamin D levels; LIHC cis rs36051895 0.559 rs72701682 chr9:5208025 A/G cg02405213 chr9:5042618 JAK2 -0.61 -9.96 -0.47 1.12e-20 Pediatric autoimmune diseases; LIHC cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg20295408 chr7:1910781 MAD1L1 -0.42 -6.16 -0.32 2.08e-9 Schizophrenia; LIHC cis rs3806843 0.771 rs801174 chr5:140112712 C/T cg16179182 chr5:140090404 VTRNA1-1 0.35 5.83 0.3 1.26e-8 Depressive symptoms (multi-trait analysis); LIHC cis rs72781680 0.699 rs72794291 chr2:23897935 C/T cg08917208 chr2:24149416 ATAD2B 0.98 8.06 0.4 1.29e-14 Lymphocyte counts; LIHC trans rs7759633 0.800 rs78733124 chr6:160997236 C/T cg06341590 chr4:57624431 NA -0.59 -6.53 -0.33 2.35e-10 Triglycerides; LIHC cis rs909002 0.849 rs6663012 chr1:32091779 T/G cg13919466 chr1:32135498 COL16A1 -0.34 -6.49 -0.33 3.01e-10 Intelligence (multi-trait analysis); LIHC cis rs1816752 0.905 rs4769348 chr13:24975113 G/A cg02811702 chr13:24901961 NA 0.25 6.1 0.31 2.8e-9 Obesity-related traits; LIHC cis rs16858210 0.874 rs11918588 chr3:183601715 C/A cg25686905 chr3:183603175 PARL -0.5 -9.35 -0.45 1.18e-18 Menopause (age at onset); LIHC cis rs7592578 0.882 rs58568707 chr2:191468987 G/A cg27211696 chr2:191398769 TMEM194B -0.61 -7.73 -0.39 1.17e-13 Diastolic blood pressure; LIHC cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg16132339 chr22:24313637 DDTL;DDT 0.77 14.73 0.62 2.17e-38 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9583531 0.689 rs6492308 chr13:111377829 T/C cg24331049 chr13:111365604 ING1 0.79 13.02 0.58 9.62e-32 Coronary artery disease; LIHC cis rs4819052 1.000 rs13052356 chr21:46663588 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 9.77 0.47 4.73e-20 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9814567 1.000 rs55913793 chr3:134285968 G/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -6.02 -0.31 4.43e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs56104184 0.775 rs56349331 chr19:49403009 T/A cg21252483 chr19:49399788 TULP2 -1.06 -12.19 -0.55 1.27e-28 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs2635047 0.638 rs2668758 chr18:44685679 A/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.41 5.92 0.3 7.73e-9 Educational attainment; LIHC trans rs561341 0.883 rs4450460 chr17:30201309 C/T cg20587970 chr11:113659929 NA 0.72 8.17 0.4 6.16e-15 Hip circumference adjusted for BMI; LIHC cis rs986417 0.901 rs3759688 chr14:60975579 A/C cg27398547 chr14:60952738 C14orf39 0.78 8.57 0.42 3.61e-16 Gut microbiota (bacterial taxa); LIHC cis rs7552404 0.731 rs11588578 chr1:76400539 T/G cg10523679 chr1:76189770 ACADM 0.6 7.19 0.36 4.05e-12 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs4474465 0.646 rs10899556 chr11:78278986 C/T cg02023728 chr11:77925099 USP35 -0.34 -6.01 -0.31 4.72e-9 Alzheimer's disease (survival time); LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.73 12.13 0.55 2.03e-28 Height; LIHC trans rs1728785 1.000 rs6499181 chr16:68593002 A/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.5 0.33 2.82e-10 Ulcerative colitis; LIHC cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg05590025 chr7:65112418 INTS4L2 -0.64 -7.14 -0.36 5.49e-12 Diabetic kidney disease; LIHC cis rs921968 0.540 rs646295 chr2:219408558 A/C cg17980119 chr2:219472607 PLCD4 0.34 5.95 0.31 6.8e-9 Mean corpuscular hemoglobin concentration; LIHC cis rs7208859 0.623 rs9897728 chr17:29108804 A/G cg13385521 chr17:29058706 SUZ12P 0.83 8.13 0.4 8e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs7131987 0.903 rs7974221 chr12:29399448 A/G cg05697976 chr12:29376483 FAR2 0.35 7.24 0.36 2.9e-12 QT interval; LIHC cis rs16877106 1.000 rs73254139 chr4:25318314 C/T cg04796973 chr4:25314218 ZCCHC4 0.62 5.85 0.3 1.18e-8 Weight; LIHC cis rs2274273 0.934 rs10139337 chr14:55742113 C/T cg01864836 chr14:55583639 NA -0.4 -6.89 -0.35 2.62e-11 Protein biomarker; LIHC cis rs10463316 0.894 rs3846712 chr5:150759813 C/A cg03212797 chr5:150827313 SLC36A1 -0.43 -6.46 -0.33 3.63e-10 Metabolite levels (Pyroglutamine); LIHC cis rs67311347 0.955 rs6599100 chr3:40447362 C/T cg00656387 chr3:40428638 ENTPD3 0.42 7.0 0.35 1.32e-11 Renal cell carcinoma; LIHC trans rs3780486 1.000 rs3780480 chr9:33163486 G/T cg04842962 chr6:43655489 MRPS18A 0.93 16.75 0.67 2.07e-46 IgG glycosylation; LIHC cis rs1451375 0.583 rs11575320 chr7:50605298 A/G cg14593290 chr7:50529359 DDC -0.6 -9.52 -0.46 3.24e-19 Malaria; LIHC cis rs7959452 0.562 rs10878975 chr12:69782044 G/C cg20891283 chr12:69753455 YEATS4 0.9 19.55 0.73 1.18e-57 Blood protein levels; LIHC cis rs1005277 0.505 rs200935 chr10:38132810 T/A cg25427524 chr10:38739819 LOC399744 -0.65 -12.6 -0.56 3.56e-30 Extrinsic epigenetic age acceleration; LIHC cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg12751644 chr20:60527061 NA -0.35 -5.89 -0.3 9e-9 Body mass index; LIHC cis rs1451375 0.617 rs9942686 chr7:50596381 G/A cg14593290 chr7:50529359 DDC 0.62 9.67 0.46 1.02e-19 Malaria; LIHC cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg10802521 chr3:52805072 NEK4 -0.44 -7.55 -0.38 3.93e-13 Bipolar disorder; LIHC cis rs2439831 0.850 rs28891769 chr15:44072860 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.5 0.42 6.09e-16 Lung cancer in ever smokers; LIHC cis rs9911578 0.835 rs1990008 chr17:56459408 C/G cg12560992 chr17:57184187 TRIM37 -0.91 -15.17 -0.63 4.21e-40 Intelligence (multi-trait analysis); LIHC cis rs4716602 0.596 rs36013171 chr7:156160511 C/T cg16983916 chr7:156159713 NA -0.32 -5.71 -0.3 2.43e-8 Anti-saccade response; LIHC cis rs8016982 0.674 rs1951615 chr14:81671762 G/A cg01989461 chr14:81687754 GTF2A1 0.7 14.71 0.62 2.59e-38 Schizophrenia; LIHC cis rs8078723 1.000 rs3213762 chr17:38178627 A/G cg17344932 chr17:38183730 MED24;SNORD124 -0.57 -8.97 -0.44 2.03e-17 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs611744 0.967 rs2600614 chr8:109198079 T/A cg21045802 chr8:109455806 TTC35 0.51 8.83 0.43 5.72e-17 Dupuytren's disease; LIHC cis rs735396 0.694 rs2264750 chr12:121450165 C/T cg25281562 chr12:121454272 C12orf43 0.36 6.1 0.31 2.81e-9 N-glycan levels; LIHC cis rs734999 0.967 rs10797433 chr1:2502010 T/C cg18854424 chr1:2615690 NA 0.32 6.84 0.35 3.57e-11 Ulcerative colitis; LIHC cis rs1564271 0.553 rs9334138 chr10:26978929 G/A cg13837822 chr10:26931731 LOC731789 0.38 7.2 0.36 3.92e-12 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; LIHC cis rs3096299 0.591 rs748940 chr16:89440757 T/A cg01788221 chr16:89496183 ANKRD11 -0.41 -6.37 -0.33 6.12e-10 Multiple myeloma (IgH translocation); LIHC trans rs3749237 0.964 rs2352975 chr3:49891885 T/C cg21659725 chr3:3221576 CRBN 0.78 12.11 0.55 2.52e-28 Resting heart rate; LIHC trans rs2270927 0.510 rs31244 chr5:75594743 G/A cg13563193 chr19:33072644 PDCD5 1.01 9.74 0.47 5.94e-20 Mean corpuscular volume; LIHC cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg25894440 chr7:65020034 NA -0.54 -6.14 -0.31 2.33e-9 Diabetic kidney disease; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg00111532 chr16:600998 SOLH 0.34 6.69 0.34 8.88e-11 Calcium levels; LIHC cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg03721293 chr16:90014378 DEF8 -0.35 -6.28 -0.32 1.06e-9 Skin colour saturation; LIHC cis rs2204008 0.811 rs2139752 chr12:38370398 C/T cg26384229 chr12:38710491 ALG10B 0.6 8.25 0.41 3.44e-15 Bladder cancer; LIHC cis rs7772486 0.754 rs9373475 chr6:146126419 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.16 0.32 2.04e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs16828019 0.929 rs111309254 chr1:41736000 A/G cg03962019 chr1:41807865 NA 0.5 7.28 0.37 2.38e-12 Intelligence (multi-trait analysis); LIHC cis rs3740540 0.507 rs10794161 chr10:126291327 C/A cg04949429 chr10:126290192 LHPP 0.44 7.2 0.36 3.97e-12 Obesity-related traits;Acute lymphoblastic leukemia (childhood); LIHC cis rs6690583 0.623 rs12042910 chr1:85452580 G/A cg22153463 chr1:85462885 MCOLN2 0.52 6.22 0.32 1.42e-9 Serum sulfate level; LIHC cis rs941408 1.000 rs1736179 chr19:2795516 T/A cg02580895 chr19:2754563 NA -0.4 -6.03 -0.31 4.2e-9 Total cholesterol levels; LIHC cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg07677032 chr17:61819896 STRADA -0.42 -6.17 -0.32 1.9e-9 Prudent dietary pattern; LIHC cis rs507080 0.922 rs585039 chr11:118563381 C/A cg04173919 chr11:118528438 PHLDB1 0.35 6.54 0.33 2.24e-10 Serum metabolite levels; LIHC cis rs10162376 1 rs10162376 chr14:81030493 C/T cg04303335 chr14:82000858 SEL1L -0.48 -7.56 -0.38 3.72e-13 Mild influenza (H1N1) infection; LIHC cis rs9818758 0.607 rs56306491 chr3:49314960 G/A cg00383909 chr3:49044727 WDR6 1.07 7.66 0.38 1.99e-13 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs3892630 0.824 rs34748593 chr19:33240447 T/C cg22980127 chr19:33182716 NUDT19 1.01 12.04 0.55 4.56e-28 Red blood cell traits; LIHC cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.98 -0.31 5.68e-9 Colorectal cancer; LIHC trans rs208520 0.608 rs3846803 chr6:66805743 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -9.13 -0.44 5.97e-18 Exhaled nitric oxide output; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg15830607 chr12:110338073 TCHP -0.57 -6.73 -0.34 7.04e-11 Systolic blood pressure; LIHC cis rs9457247 0.967 rs1794694 chr6:167404751 T/C cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs7412746 0.658 rs897815 chr1:150879101 C/T cg18016565 chr1:150552671 MCL1 -0.49 -9.22 -0.45 3.19e-18 Melanoma; LIHC cis rs258324 0.720 rs154663 chr16:89726035 T/C cg04240660 chr16:89714849 CHMP1A 0.58 7.23 0.36 3.17e-12 Height; LIHC cis rs35110281 0.811 rs9980185 chr21:45057905 A/G cg21573476 chr21:45109991 RRP1B -0.5 -9.51 -0.46 3.5e-19 Mean corpuscular volume; LIHC cis rs6430585 0.591 rs72970243 chr2:136484232 G/A cg07169764 chr2:136633963 MCM6 0.66 8.51 0.42 5.53e-16 Corneal structure; LIHC cis rs1059312 1.000 rs12814773 chr12:129280786 C/T cg09035930 chr12:129282057 SLC15A4 0.69 13.29 0.58 8.71e-33 Systemic lupus erythematosus; LIHC cis rs8078723 1.000 rs7214085 chr17:38169095 T/C cg17344932 chr17:38183730 MED24;SNORD124 -0.56 -8.94 -0.44 2.44e-17 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); LIHC cis rs9649213 0.593 rs6947208 chr7:97912204 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.37 -5.8 -0.3 1.54e-8 Prostate cancer (SNP x SNP interaction); LIHC cis rs992157 0.835 rs2292555 chr2:219146882 G/C cg20019365 chr2:219134978 PNKD;AAMP -0.77 -12.08 -0.55 3.06e-28 Colorectal cancer; LIHC cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg18357526 chr6:26021779 HIST1H4A -0.86 -12.4 -0.56 2.09e-29 Intelligence (multi-trait analysis); LIHC trans rs1005277 0.505 rs13503 chr10:38239843 C/A cg23533926 chr12:111358616 MYL2 0.34 6.7 0.34 8.44e-11 Extrinsic epigenetic age acceleration; LIHC cis rs7772486 0.875 rs11155452 chr6:146424631 C/T cg13319975 chr6:146136371 FBXO30 -0.38 -6.11 -0.31 2.78e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg00280220 chr17:61926910 NA 0.43 6.88 0.35 2.79e-11 Prudent dietary pattern; LIHC cis rs17102423 0.594 rs1998688 chr14:65562306 C/G cg16583315 chr14:65563665 MAX 0.36 7.19 0.36 4.01e-12 Obesity-related traits; LIHC cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg21724239 chr8:58056113 NA 0.63 7.32 0.37 1.76e-12 Developmental language disorder (linguistic errors); LIHC cis rs875971 0.660 rs10950044 chr7:66042976 A/G cg14393609 chr7:65229607 NA -0.38 -6.03 -0.31 4.25e-9 Aortic root size; LIHC cis rs875971 0.545 rs10950025 chr7:65623933 G/A cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.5 0.38 5.5e-13 Aortic root size; LIHC cis rs919433 0.617 rs4850807 chr2:198575975 G/A cg10820045 chr2:198174542 NA -0.51 -7.82 -0.39 6.57e-14 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC trans rs561341 0.769 rs559228 chr17:30294527 T/C cg20587970 chr11:113659929 NA -1.38 -11.72 -0.54 6.87e-27 Hip circumference adjusted for BMI; LIHC cis rs9326248 0.953 rs634960 chr11:117072963 T/C cg11861562 chr11:117069780 TAGLN -0.48 -7.88 -0.39 4.56e-14 Blood protein levels; LIHC cis rs10883723 0.668 rs12414479 chr10:104420902 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.71 8.13 0.4 7.85e-15 Allergic disease (asthma, hay fever or eczema); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg11399053 chr11:130781648 SNX19 0.45 6.66 0.34 1.08e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.56 9.4 0.45 7.87e-19 Bipolar disorder; LIHC cis rs1005277 0.579 rs1780145 chr10:38537070 A/G cg18963800 chr10:38644991 HSD17B7P2 -0.43 -6.34 -0.32 7.08e-10 Extrinsic epigenetic age acceleration; LIHC cis rs7937890 1.000 rs2970334 chr11:14329355 C/T cg22961513 chr11:14280813 SPON1 0.47 7.2 0.36 3.8e-12 Mitochondrial DNA levels; LIHC cis rs7520050 0.966 rs7539932 chr1:46292354 C/T cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.75 0.3 2.03e-8 Red blood cell count;Reticulocyte count; LIHC cis rs3806843 0.966 rs11953833 chr5:140155123 T/A cg26395211 chr5:140044315 WDR55 -0.41 -5.99 -0.31 5.27e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs17685 0.753 rs6465000 chr7:75787417 G/A cg04592579 chr7:75616294 TMEM120A 0.4 6.94 0.35 1.97e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7208859 0.673 rs73263981 chr17:28920502 A/G cg13385521 chr17:29058706 SUZ12P 0.57 5.72 0.3 2.3e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10751667 0.857 rs7481221 chr11:966813 G/C cg10932868 chr11:921992 NA 0.41 7.67 0.38 1.82e-13 Alzheimer's disease (late onset); LIHC cis rs6952808 0.929 rs1801368 chr7:1976457 C/T cg20295408 chr7:1910781 MAD1L1 -0.45 -6.51 -0.33 2.66e-10 Bipolar disorder and schizophrenia; LIHC cis rs13108904 0.557 rs1250097 chr4:1238338 C/T cg02475777 chr4:1388615 CRIPAK -0.49 -7.36 -0.37 1.35e-12 Obesity-related traits; LIHC cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.77 0.39 9.06e-14 Prudent dietary pattern; LIHC trans rs916888 0.531 rs183211 chr17:44788310 G/A cg22968622 chr17:43663579 NA 0.48 6.99 0.35 1.49e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7639513 0.767 rs13060705 chr3:12710016 C/A cg23032965 chr3:12705835 RAF1 0.65 7.85 0.39 5.27e-14 Itch intensity from mosquito bite; LIHC cis rs172166 0.637 rs1225597 chr6:28162087 C/T cg23485639 chr6:28045615 ZNF165 0.37 5.89 0.3 9.34e-9 Cardiac Troponin-T levels; LIHC cis rs9900497 0.604 rs12949049 chr17:19653310 A/G cg22552966 chr17:19620595 SLC47A2 0.47 9.56 0.46 2.41e-19 Response to paliperidone in schizophrenia (CGI-S score); LIHC cis rs2274273 0.901 rs8011288 chr14:55735112 C/T cg01864836 chr14:55583639 NA -0.4 -7.22 -0.36 3.35e-12 Protein biomarker; LIHC cis rs7020830 0.825 rs13297152 chr9:37075623 C/T cg14294708 chr9:37120828 ZCCHC7 1.14 23.07 0.78 1.06e-71 Schizophrenia; LIHC cis rs57590327 0.503 rs17019299 chr3:81851643 A/G cg07356753 chr3:81810745 GBE1 -0.52 -7.98 -0.4 2.18e-14 Extraversion; LIHC cis rs2731664 0.765 rs2630766 chr5:176874941 A/C cg23176889 chr5:176863531 GRK6 -0.72 -12.55 -0.56 5.69e-30 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg13395646 chr4:1353034 KIAA1530 -0.4 -6.34 -0.32 7.39e-10 Obesity-related traits; LIHC cis rs881375 0.678 rs1930782 chr9:123687905 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 6.3 0.32 9.19e-10 Rheumatoid arthritis; LIHC cis rs244293 0.965 rs244356 chr17:53193809 G/T cg19360675 chr17:53046073 COX11;STXBP4 -0.5 -7.47 -0.37 6.93e-13 Menarche (age at onset); LIHC cis rs6582630 0.555 rs10785454 chr12:38476260 C/T cg26384229 chr12:38710491 ALG10B 0.69 9.62 0.46 1.47e-19 Drug-induced liver injury (flucloxacillin); LIHC cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 11.42 0.53 8.54e-26 Alzheimer's disease; LIHC cis rs9902453 0.765 rs2628191 chr17:28051140 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -13.56 -0.59 7.82e-34 Coffee consumption (cups per day); LIHC cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg12463550 chr7:65579703 CRCP 0.7 7.35 0.37 1.43e-12 Diabetic kidney disease; LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg11494091 chr17:61959527 GH2 0.45 8.19 0.41 5.16e-15 Prudent dietary pattern; LIHC cis rs4919694 1.000 rs79254677 chr10:104691567 A/G cg04362960 chr10:104952993 NT5C2 1.13 8.79 0.43 7.61e-17 Arsenic metabolism; LIHC cis rs8060686 0.516 rs12599238 chr16:68276235 G/A cg09835421 chr16:68378352 PRMT7 -0.53 -6.05 -0.31 3.86e-9 HDL cholesterol;Metabolic syndrome; LIHC cis rs55665837 1.000 rs11023229 chr11:14461001 G/C cg19336497 chr11:14380999 RRAS2 -0.44 -7.99 -0.4 2.15e-14 Vitamin D levels; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg20609493 chr15:60420227 NA 0.38 6.17 0.32 1.89e-9 Cognitive function; LIHC cis rs6545883 0.929 rs6707830 chr2:61749472 G/A cg14146966 chr2:61757674 XPO1 0.48 8.48 0.42 6.93e-16 Tuberculosis; LIHC cis rs9818758 0.556 rs9814987 chr3:49207849 T/C cg07636037 chr3:49044803 WDR6 -0.75 -7.61 -0.38 2.65e-13 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs7618501 0.521 rs34654589 chr3:49911449 C/G cg05623727 chr3:50126028 RBM5 0.37 6.16 0.32 2.08e-9 Intelligence (multi-trait analysis); LIHC cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg00149659 chr3:10157352 C3orf10 0.6 6.57 0.33 1.84e-10 Alzheimer's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg04047827 chr16:24740859 TNRC6A 0.39 6.04 0.31 3.98e-9 Pancreatic cancer; LIHC cis rs8062405 0.964 rs62036614 chr16:28824685 T/C cg16576597 chr16:28551801 NUPR1 0.37 5.86 0.3 1.11e-8 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs7078219 0.505 rs10883365 chr10:101287764 C/T cg06854084 chr10:101292507 NKX2-3 -0.32 -5.92 -0.31 7.68e-9 Dental caries; LIHC cis rs6952808 0.529 rs73038442 chr7:2139457 C/T cg21782813 chr7:2030301 MAD1L1 0.38 6.48 0.33 3.16e-10 Bipolar disorder and schizophrenia; LIHC cis rs8180040 0.726 rs11130110 chr3:47000606 T/C cg16586182 chr3:47516702 SCAP -0.46 -8.27 -0.41 3.07e-15 Colorectal cancer; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg10106725 chr4:3071494 NA 0.35 6.13 0.31 2.36e-9 Cognitive function; LIHC cis rs1639906 0.895 rs78469080 chr7:2200729 G/A cg04267008 chr7:1944627 MAD1L1 0.46 6.07 0.31 3.38e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg25894440 chr7:65020034 NA -0.52 -6.14 -0.32 2.32e-9 Diabetic kidney disease; LIHC cis rs11758351 0.660 rs77337633 chr6:26233610 T/C cg03854865 chr6:26224070 HIST1H3E 0.59 6.48 0.33 3.27e-10 Gout;Renal underexcretion gout; LIHC cis rs10492096 0.945 rs2041386 chr12:6562538 C/T cg13857086 chr12:6580257 VAMP1 0.59 5.97 0.31 6.06e-9 Hip geometry; LIHC cis rs7572733 0.515 rs1836234 chr2:198882873 T/G cg10820045 chr2:198174542 NA 0.43 6.51 0.33 2.64e-10 Dermatomyositis; LIHC cis rs9486715 0.867 rs4598081 chr6:96975227 A/G cg06623918 chr6:96969491 KIAA0776 0.86 15.58 0.64 9.67e-42 Headache; LIHC cis rs965469 0.779 rs6051740 chr20:3301165 T/C cg25506879 chr20:3388711 C20orf194 -0.5 -6.21 -0.32 1.49e-9 IFN-related cytopenia; LIHC cis rs10484885 0.878 rs72921937 chr6:90579863 T/G cg13799429 chr6:90582589 CASP8AP2 -0.69 -6.54 -0.33 2.29e-10 QRS interval (sulfonylurea treatment interaction); LIHC cis rs2153535 0.623 rs6597338 chr6:8533508 A/C cg07606381 chr6:8435919 SLC35B3 0.79 11.72 0.54 6.76e-27 Motion sickness; LIHC cis rs35306767 0.903 rs12244253 chr10:889320 G/T cg26597838 chr10:835615 NA 1.2 14.83 0.63 8.74e-39 Eosinophil percentage of granulocytes; LIHC cis rs10838687 0.736 rs7120158 chr11:47265194 G/C cg26139080 chr11:47293733 MADD -0.42 -5.89 -0.3 8.99e-9 Proinsulin levels; LIHC cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg03452623 chr4:187889614 NA -0.31 -7.89 -0.39 4.18e-14 Lobe attachment (rater-scored or self-reported); LIHC trans rs561341 0.882 rs72825748 chr17:30367396 G/A cg20587970 chr11:113659929 NA -1.44 -12.1 -0.55 2.8e-28 Hip circumference adjusted for BMI; LIHC cis rs9911578 0.967 rs302842 chr17:56728102 C/G cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC trans rs6934970 1.000 rs12215023 chr6:113103851 A/G cg09308777 chr6:169852575 NA 0.64 6.33 0.32 7.82e-10 Bipolar disorder (body mass index interaction); LIHC cis rs9929218 1.000 rs35069703 chr16:68789445 G/A cg01231543 chr16:68741748 NA 0.37 5.79 0.3 1.61e-8 Colorectal cancer; LIHC cis rs66573146 0.572 rs67252699 chr4:6946411 A/G cg15105060 chr4:7024189 TBC1D14 -0.7 -6.31 -0.32 8.73e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg06634786 chr22:41940651 POLR3H -0.76 -8.32 -0.41 2.14e-15 Vitiligo; LIHC cis rs875971 0.895 rs1974769 chr7:65950614 G/A cg11764359 chr7:65958608 NA 0.88 15.89 0.65 5.48e-43 Aortic root size; LIHC cis rs743757 1.000 rs743857 chr3:50493550 T/C cg09545109 chr3:50388910 TUSC4;CYB561D2 0.51 7.95 0.4 2.66e-14 Diastolic blood pressure; LIHC cis rs1401999 0.690 rs6773408 chr3:183716609 G/T cg01324343 chr3:183735012 ABCC5 0.62 10.28 0.49 8.58e-22 Anterior chamber depth; LIHC cis rs2842992 0.789 rs7758895 chr6:160193465 T/C cg16489826 chr6:160211363 TCP1;MRPL18 0.5 8.78 0.43 8.08e-17 Age-related macular degeneration (geographic atrophy); LIHC cis rs7220401 0.512 rs2289629 chr17:27959903 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.65 7.92 0.39 3.47e-14 Coronary artery disease; LIHC cis rs780096 0.506 rs1647285 chr2:27714511 A/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.71 -0.34 8.16e-11 Total body bone mineral density; LIHC cis rs8017423 0.647 rs10132599 chr14:90815342 C/T cg04374321 chr14:90722782 PSMC1 -0.47 -7.0 -0.35 1.4e-11 Mortality in heart failure; LIHC cis rs548181 0.736 rs1941558 chr11:125425606 C/T cg03464685 chr11:125439445 EI24 1.39 14.68 0.62 3.59e-38 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg16497277 chr3:49208875 KLHDC8B -0.49 -6.21 -0.32 1.56e-9 Menarche (age at onset); LIHC cis rs9611565 0.879 rs4820437 chr22:41761290 T/C cg03806693 chr22:41940476 POLR3H -0.51 -6.61 -0.34 1.52e-10 Vitiligo; LIHC cis rs2479724 0.935 rs62396748 chr6:41782007 A/G cg17623882 chr6:41773611 USP49 0.55 8.31 0.41 2.27e-15 Menarche (age at onset); LIHC cis rs921968 0.565 rs3770219 chr2:219619766 T/C cg02985541 chr2:219472218 PLCD4 -0.37 -6.43 -0.33 4.25e-10 Mean corpuscular hemoglobin concentration; LIHC cis rs1499280 1.000 rs9291995 chr5:52099436 T/C cg21153758 chr5:52083992 ITGA1;PELO -0.63 -5.88 -0.3 9.75e-9 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Reticulocyte count;Reticulocyte fraction of red cells;Immature fraction of reticulocytes; LIHC cis rs1853665 0.580 rs6557201 chr6:150272567 T/C cg16301758 chr6:150275521 NA -0.41 -6.21 -0.32 1.58e-9 Radiation response; LIHC cis rs918629 0.567 rs2548594 chr5:95244414 C/T cg10483112 chr5:95245456 ELL2 -0.38 -7.14 -0.36 5.71e-12 IgG glycosylation; LIHC cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg02290350 chr8:58132656 NA 0.41 8.36 0.41 1.61e-15 Developmental language disorder (linguistic errors); LIHC cis rs2637266 0.783 rs11001866 chr10:78486774 C/T cg18941641 chr10:78392320 NA 0.27 5.82 0.3 1.33e-8 Pulmonary function; LIHC cis rs951366 0.764 rs823143 chr1:205743425 A/C cg07167872 chr1:205819463 PM20D1 0.59 8.57 0.42 3.53e-16 Menarche (age at onset); LIHC cis rs7772486 0.790 rs2247429 chr6:146217769 T/C cg23711669 chr6:146136114 FBXO30 0.71 12.36 0.56 2.97e-29 Lobe attachment (rater-scored or self-reported); LIHC cis rs7635838 0.617 rs346071 chr3:11305584 A/T cg00170343 chr3:11313890 ATG7 -0.6 -10.27 -0.49 9.51e-22 HDL cholesterol; LIHC cis rs9733 0.596 rs11807058 chr1:150640475 G/A cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg20607798 chr8:58055168 NA 0.65 8.15 0.4 6.88e-15 Developmental language disorder (linguistic errors); LIHC cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg02951883 chr7:2050386 MAD1L1 0.8 13.49 0.59 1.48e-33 Bipolar disorder and schizophrenia; LIHC trans rs561341 0.941 rs2428338 chr17:30299629 T/C cg20587970 chr11:113659929 NA -1.25 -10.84 -0.51 9.77e-24 Hip circumference adjusted for BMI; LIHC cis rs56104184 0.723 rs73063515 chr19:49407715 C/T cg15549821 chr19:49342101 PLEKHA4 -0.65 -6.07 -0.31 3.36e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; LIHC cis rs861020 0.771 rs1962735 chr1:210012102 A/G cg05527609 chr1:210001259 C1orf107 0.98 15.84 0.65 9.23e-43 Orofacial clefts; LIHC cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg17971929 chr21:40555470 PSMG1 -0.52 -7.92 -0.39 3.39e-14 Cognitive function; LIHC cis rs6500602 0.627 rs934929 chr16:4587789 A/G cg08645402 chr16:4508243 NA -0.34 -5.97 -0.31 6.07e-9 Schizophrenia; LIHC cis rs10751667 0.643 rs12278229 chr11:946985 A/G cg06064525 chr11:970664 AP2A2 -0.55 -14.54 -0.62 1.22e-37 Alzheimer's disease (late onset); LIHC cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg21747090 chr2:27597821 SNX17 -0.46 -6.85 -0.35 3.36e-11 Menopause (age at onset); LIHC cis rs7264396 0.635 rs2425166 chr20:34439391 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.83 -0.51 1.07e-23 Total cholesterol levels; LIHC cis rs16958440 1.000 rs62096469 chr18:44638298 A/G cg17192377 chr18:44677553 HDHD2 0.61 6.9 0.35 2.59e-11 Sitting height ratio; LIHC cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg22528358 chr1:107598549 PRMT6 -0.67 -11.0 -0.51 2.58e-24 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs651907 0.557 rs11917682 chr3:101355427 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.68 10.86 0.51 8.58e-24 Colorectal cancer; LIHC cis rs7412746 0.611 rs10788794 chr1:150728676 T/C cg15448220 chr1:150897856 SETDB1 0.41 6.31 0.32 8.49e-10 Melanoma; LIHC cis rs2075371 0.933 rs1868784 chr7:133945932 A/G cg11752832 chr7:134001865 SLC35B4 0.51 7.73 0.39 1.18e-13 Mean platelet volume; LIHC cis rs713477 1.000 rs12893964 chr14:55912268 T/C cg13175173 chr14:55914753 NA -0.33 -7.66 -0.38 1.99e-13 Pediatric bone mineral content (femoral neck); LIHC cis rs360798 0.532 rs1553832 chr2:63013515 C/G cg17519650 chr2:63277830 OTX1 -0.54 -8.37 -0.41 1.47e-15 Coronary artery disease; LIHC cis rs7520050 0.966 rs61783200 chr1:46297403 T/C cg08160980 chr1:46668840 C1orf190;POMGNT1 0.4 5.75 0.3 2.03e-8 Red blood cell count;Reticulocyte count; LIHC cis rs7666738 0.830 rs17027102 chr4:98919221 A/G cg05340658 chr4:99064831 C4orf37 -0.66 -12.36 -0.56 2.96e-29 Colonoscopy-negative controls vs population controls; LIHC cis rs72781680 0.582 rs72783611 chr2:24291445 C/T cg06627628 chr2:24431161 ITSN2 -0.64 -7.42 -0.37 9.34e-13 Lymphocyte counts; LIHC cis rs2991971 1.000 rs2934859 chr1:46017836 C/T cg15605315 chr1:45957053 TESK2 0.45 5.93 0.31 7.36e-9 High light scatter reticulocyte count; LIHC cis rs6500602 0.702 rs3761680 chr16:4524060 C/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 5.91 0.3 8.5e-9 Schizophrenia; LIHC cis rs9814567 1.000 rs4535272 chr3:134299916 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 12.07 0.55 3.48e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs11332131 1 rs11332131 chr17:57926391 GT/G cg02344993 chr17:57696989 CLTC 0.46 7.61 0.38 2.6e-13 Platelet distribution width; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg06943149 chr12:77157476 ZDHHC17 0.41 6.11 0.31 2.74e-9 Pancreatic cancer; LIHC cis rs6964587 1.000 rs10234290 chr7:91716951 T/C cg17063962 chr7:91808500 NA 1.01 19.29 0.72 1.22e-56 Breast cancer; LIHC cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg10935138 chr17:73851978 WBP2 0.74 10.2 0.48 1.67e-21 Psoriasis; LIHC cis rs7264396 0.635 rs6060696 chr20:34522060 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.66 -10.62 -0.5 6.08e-23 Total cholesterol levels; LIHC cis rs6687430 0.562 rs6676491 chr1:10633421 A/C cg17425144 chr1:10567563 PEX14 0.46 8.17 0.4 5.97e-15 Hand grip strength; LIHC cis rs2404602 0.684 rs2454451 chr15:76861461 G/T cg03037974 chr15:76606532 NA 0.64 10.91 0.51 5.47e-24 Blood metabolite levels; LIHC trans rs7246657 0.943 rs10417844 chr19:37837587 C/T cg10208301 chr11:6592745 DNHD1 0.48 6.96 0.35 1.71e-11 Coronary artery calcification; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08733086 chr1:154947035 CKS1B;SHC1 -0.53 -6.62 -0.34 1.39e-10 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs2073300 1.000 rs6137961 chr20:23443102 G/T cg12062639 chr20:23401060 NAPB 0.84 9.99 0.48 8.65e-21 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs1712517 0.873 rs7894240 chr10:105000369 T/C cg05636881 chr10:105038444 INA -0.38 -6.08 -0.31 3.27e-9 Migraine; LIHC cis rs12701220 0.842 rs10236293 chr7:1032637 G/A cg26769984 chr7:1090371 C7orf50 0.63 7.69 0.38 1.6e-13 Bronchopulmonary dysplasia; LIHC cis rs12220238 0.915 rs10824148 chr10:76078014 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.61 5.79 0.3 1.58e-8 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg06481639 chr22:41940642 POLR3H -0.59 -6.12 -0.31 2.61e-9 Vitiligo; LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg02993280 chr1:107599747 PRMT6 -0.62 -9.75 -0.47 5.5e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs932541 1.000 rs6111151 chr20:16456032 G/T cg17003395 chr20:16555519 KIF16B 0.42 5.72 0.3 2.38e-8 Intelligence; LIHC cis rs2637266 0.967 rs12254242 chr10:78352934 T/C cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs1400745 0.756 rs799683 chr14:35349236 G/A cg05294307 chr14:35346193 BAZ1A -0.46 -7.67 -0.38 1.79e-13 Monocyte count; LIHC cis rs3008870 0.920 rs1925413 chr1:67417101 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.94 16.24 0.66 2.29e-44 Lymphocyte percentage of white cells; LIHC cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg04234412 chr22:24373322 LOC391322 -0.68 -10.21 -0.48 1.57e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg06140118 chr16:68056778 DDX28;DUS2L -0.42 -6.18 -0.32 1.79e-9 Immature fraction of reticulocytes; LIHC cis rs780096 0.526 rs4582 chr2:27604279 A/G cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.43 -6.6 -0.34 1.55e-10 Total body bone mineral density; LIHC cis rs7618501 1.000 rs2271961 chr3:49878113 C/T cg21467203 chr3:49911342 NA 0.4 6.94 0.35 1.95e-11 Intelligence (multi-trait analysis); LIHC cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg05564831 chr3:52568323 NT5DC2 0.35 5.84 0.3 1.21e-8 Bipolar disorder; LIHC cis rs963731 0.649 rs2278914 chr2:39218552 G/A cg04010122 chr2:39346883 SOS1 -0.7 -5.96 -0.31 6.38e-9 Corticobasal degeneration; LIHC cis rs4478037 0.822 rs4528891 chr3:33121392 G/T cg27203090 chr3:33138513 GLB1;TMPPE -0.51 -6.47 -0.33 3.48e-10 Major depressive disorder; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg26614578 chr12:113623930 C12orf52;DDX54 0.49 7.99 0.4 2.1e-14 Cognitive function; LIHC cis rs854765 0.647 rs2974999 chr17:17997547 T/G cg04398451 chr17:18023971 MYO15A -0.67 -11.06 -0.51 1.61e-24 Total body bone mineral density; LIHC cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg11062466 chr8:58055876 NA 0.5 7.3 0.37 2.08e-12 Developmental language disorder (linguistic errors); LIHC cis rs769267 0.896 rs10405625 chr19:19579046 T/G cg03709012 chr19:19516395 GATAD2A 1.03 18.52 0.71 1.52e-53 Tonsillectomy; LIHC cis rs12286929 0.699 rs1048932 chr11:115044850 C/A cg04055981 chr11:115044050 NA -0.41 -6.6 -0.34 1.57e-10 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC trans rs1512777 0.649 rs1916252 chr3:144436001 C/T cg06253862 chr6:160201362 SNORA20;TCP1 0.48 6.31 0.32 8.44e-10 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); LIHC cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs3823572 0.542 rs28529474 chr7:133634908 C/T cg03336402 chr7:133662267 EXOC4 0.47 5.84 0.3 1.22e-8 Intelligence (multi-trait analysis); LIHC cis rs2066819 1.000 rs2306693 chr12:56680531 T/C cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs2067615 0.507 rs10746064 chr12:107086245 G/T cg15890332 chr12:107067104 RFX4 0.27 6.31 0.32 8.71e-10 Heart rate; LIHC cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg04727924 chr7:799746 HEATR2 -0.64 -8.81 -0.43 6.4e-17 Cerebrospinal P-tau181p levels; LIHC cis rs4742903 0.967 rs10820605 chr9:106881402 C/T cg14250997 chr9:106856677 SMC2 0.39 6.74 0.34 6.89e-11 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs35306767 0.953 rs11253517 chr10:970524 A/G cg20503657 chr10:835505 NA -0.82 -9.32 -0.45 1.48e-18 Eosinophil percentage of granulocytes; LIHC cis rs10193935 0.818 rs10221927 chr2:42546680 A/C cg27598129 chr2:42591480 NA -0.73 -11.25 -0.52 3.46e-25 Colonoscopy-negative controls vs population controls; LIHC trans rs75804782 0.641 rs41264155 chr2:239342096 G/A cg01134436 chr17:81009848 B3GNTL1 0.84 7.19 0.36 4.09e-12 Morning vs. evening chronotype;Chronotype; LIHC trans rs61931739 0.534 rs1586410 chr12:33999142 C/T cg26384229 chr12:38710491 ALG10B 0.49 6.79 0.34 5.01e-11 Morning vs. evening chronotype; LIHC cis rs9916302 0.904 rs9898773 chr17:37532507 C/G cg00129232 chr17:37814104 STARD3 0.4 6.34 0.32 7.42e-10 Glomerular filtration rate (creatinine); LIHC cis rs34779708 0.931 rs72789690 chr10:35382817 T/C cg03585969 chr10:35415529 CREM 0.88 13.22 0.58 1.62e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs11958404 1.000 rs72816531 chr5:157413079 A/G cg05962755 chr5:157440814 NA 0.86 10.11 0.48 3.51e-21 IgG glycosylation; LIHC cis rs798554 0.616 rs1636252 chr7:2884993 A/C cg19717773 chr7:2847554 GNA12 -0.32 -5.89 -0.3 9.07e-9 Height; LIHC cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg13126279 chr21:47581558 C21orf56 0.47 7.9 0.39 3.85e-14 Testicular germ cell tumor; LIHC cis rs2204008 0.774 rs11616004 chr12:38278822 G/A cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 3.16e-23 Bladder cancer; LIHC cis rs9814567 0.712 rs4955545 chr3:134332926 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs12497850 0.897 rs7432989 chr3:49105136 A/G cg06212747 chr3:49208901 KLHDC8B 0.59 7.56 0.38 3.65e-13 Parkinson's disease; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg08659621 chr20:48552817 RNF114 0.46 6.27 0.32 1.1e-9 Pancreatic cancer; LIHC cis rs797680 0.856 rs535760 chr1:93728758 T/A cg15093775 chr1:93646470 TMED5;CCDC18 0.33 5.77 0.3 1.78e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC trans rs1005277 0.579 rs2474572 chr10:38385316 A/G cg27523141 chr10:43048294 ZNF37B 0.37 6.4 0.33 5.12e-10 Extrinsic epigenetic age acceleration; LIHC cis rs9910055 0.529 rs170637 chr17:42186868 C/T cg19774624 chr17:42201019 HDAC5 0.52 6.64 0.34 1.25e-10 Total body bone mineral density; LIHC cis rs10878977 0.565 rs11177656 chr12:69809883 T/C cg17330252 chr12:69809627 NA 0.37 5.82 0.3 1.34e-8 Colorectal cancer; LIHC cis rs7432375 0.901 rs1017882 chr3:136357705 T/C cg21827317 chr3:136751795 NA 0.44 5.85 0.3 1.14e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg19318889 chr4:1322082 MAEA 0.67 10.68 0.5 3.64e-23 Longevity; LIHC cis rs7116495 1.000 rs1939242 chr11:71753582 C/T cg26138937 chr11:71823887 C11orf51 -0.72 -7.31 -0.37 1.87e-12 Severe influenza A (H1N1) infection; LIHC cis rs9325144 0.560 rs11182952 chr12:38636278 C/A cg26384229 chr12:38710491 ALG10B -0.61 -8.43 -0.41 1.01e-15 Morning vs. evening chronotype; LIHC cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.99 8.93 0.43 2.62e-17 Platelet count; LIHC cis rs9649465 1.000 rs2299983 chr7:123356642 C/G cg03229431 chr7:123269106 ASB15 -0.37 -7.96 -0.4 2.58e-14 Migraine; LIHC cis rs35110281 0.591 rs162369 chr21:44931965 G/A cg04455712 chr21:45112962 RRP1B 0.44 7.48 0.37 6.45e-13 Mean corpuscular volume; LIHC cis rs11761441 0.602 rs7794663 chr7:94105 C/T cg25149888 chr7:81075 NA -0.26 -5.74 -0.3 2.1e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs11608355 0.545 rs6606724 chr12:109905179 T/C cg05360138 chr12:110035743 NA 0.95 10.85 0.51 9.18e-24 Neuroticism; LIHC cis rs921968 0.643 rs532475 chr2:219434208 C/T cg02985541 chr2:219472218 PLCD4 0.44 8.39 0.41 1.28e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs7264396 0.790 rs6060562 chr20:34282053 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.7 -11.94 -0.54 1.07e-27 Total cholesterol levels; LIHC cis rs929354 0.772 rs4716460 chr7:156970054 T/C cg17757837 chr7:157058334 UBE3C 0.74 12.0 0.54 6.44e-28 Body mass index; LIHC cis rs79149102 0.579 rs74023936 chr15:75362084 C/T cg16226627 chr15:75307476 SCAMP5 0.49 8.59 0.42 3.09e-16 Lung cancer; LIHC cis rs4595586 0.545 rs12831116 chr12:39401456 C/T cg26384229 chr12:38710491 ALG10B 0.54 6.48 0.33 3.27e-10 Morning vs. evening chronotype; LIHC cis rs7100689 0.646 rs4601708 chr10:82119583 G/T cg00277334 chr10:82204260 NA -0.56 -7.06 -0.36 9.57e-12 Post bronchodilator FEV1; LIHC cis rs9814567 1.000 rs62271514 chr3:134298554 A/G cg06541857 chr3:134203789 ANAPC13;CEP63 0.4 5.88 0.3 9.6e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs295140 0.605 rs1436164 chr2:201158411 C/T cg23649088 chr2:200775458 C2orf69 -0.46 -6.4 -0.33 5.2e-10 QT interval; LIHC cis rs703842 1.000 rs10783848 chr12:58196528 G/A cg18357645 chr12:58087776 OS9 -0.44 -7.03 -0.36 1.12e-11 Multiple sclerosis; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg16944159 chr2:62132759 COMMD1 0.39 6.21 0.32 1.53e-9 Cognitive function; LIHC cis rs10792665 0.649 rs12808296 chr11:82740116 A/C cg24227371 chr11:82718527 RAB30 -0.38 -9.16 -0.44 5.06e-18 Obesity-related traits; LIHC trans rs1814175 0.645 rs1851869 chr11:49960552 T/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC trans rs1814175 0.645 rs1851844 chr11:50021773 T/C cg18944383 chr4:111397179 ENPEP 0.28 7.17 0.36 4.79e-12 Height; LIHC cis rs2777491 1.000 rs2730055 chr15:41735708 C/A cg18705301 chr15:41695430 NDUFAF1 -0.6 -9.29 -0.45 1.85e-18 Ulcerative colitis; LIHC cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg11494091 chr17:61959527 GH2 0.43 8.03 0.4 1.59e-14 Prudent dietary pattern; LIHC cis rs4665809 1.000 rs10170359 chr2:26272219 G/T cg04944784 chr2:26401820 FAM59B -0.67 -8.4 -0.41 1.24e-15 Gut microbiome composition (summer); LIHC trans rs875971 1.000 rs778710 chr7:65854834 T/C cg10756647 chr7:56101905 PSPH 0.45 6.55 0.33 2.06e-10 Aortic root size; LIHC cis rs597539 0.652 rs482172 chr11:68668437 C/A cg04772025 chr11:68637568 NA 0.46 6.03 0.31 4.25e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs6500602 0.627 rs841231 chr16:4583147 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.45 -6.57 -0.33 1.89e-10 Schizophrenia; LIHC cis rs6456156 0.526 rs3093025 chr6:167532731 A/G cg23791538 chr6:167370224 RNASET2 0.37 5.81 0.3 1.4e-8 Primary biliary cholangitis; LIHC cis rs11955398 0.678 rs1824120 chr5:59997929 G/A cg02684056 chr5:59996105 DEPDC1B 0.4 5.98 0.31 5.68e-9 Intelligence (multi-trait analysis); LIHC cis rs597539 0.690 rs552517 chr11:68625286 T/G cg06028808 chr11:68637592 NA 0.44 5.74 0.3 2.1e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs12644436 0.587 rs11723700 chr4:88780084 T/A cg06891869 chr4:88767617 MEPE 0.43 7.58 0.38 3.26e-13 HIV-1 viral setpoint; LIHC cis rs6782228 0.509 rs6780447 chr3:128413808 T/C cg16766828 chr3:128327626 NA -0.38 -6.03 -0.31 4.2e-9 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; LIHC trans rs801193 1.000 rs2659889 chr7:66217112 A/G cg26939375 chr7:64535504 NA 0.42 6.71 0.34 8.22e-11 Aortic root size; LIHC cis rs780096 0.526 rs75855890 chr2:27625005 G/T cg11618577 chr2:27665543 KRTCAP3 -0.43 -5.99 -0.31 5.39e-9 Total body bone mineral density; LIHC cis rs12579753 0.879 rs11115008 chr12:82164859 C/T cg07988820 chr12:82153109 PPFIA2 -0.46 -5.72 -0.3 2.27e-8 Resting heart rate; LIHC cis rs67478160 0.634 rs2144080 chr14:104258761 A/C cg01849466 chr14:104193079 ZFYVE21 -0.51 -8.72 -0.43 1.26e-16 Schizophrenia; LIHC cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg05025164 chr4:1340916 KIAA1530 0.76 11.89 0.54 1.67e-27 Longevity; LIHC cis rs9733 0.596 rs6661872 chr1:150628357 C/G cg18016565 chr1:150552671 MCL1 0.59 11.81 0.54 3.06e-27 Tonsillectomy; LIHC cis rs7542091 0.579 rs34638782 chr1:210032055 C/G cg05527609 chr1:210001259 C1orf107 -0.52 -7.73 -0.39 1.19e-13 Monobrow; LIHC cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg20607798 chr8:58055168 NA 0.63 8.04 0.4 1.51e-14 Developmental language disorder (linguistic errors); LIHC cis rs9517320 0.534 rs9554478 chr13:99187792 G/A cg20487152 chr13:99095054 FARP1 -0.38 -6.21 -0.32 1.52e-9 Longevity; LIHC cis rs4555082 0.718 rs75139030 chr14:105710853 A/AG cg13114125 chr14:105738426 BRF1 -0.81 -10.46 -0.49 2.15e-22 Mean platelet volume;Platelet distribution width; LIHC cis rs651907 0.535 rs12633089 chr3:101528763 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC trans rs801193 1.000 rs6975195 chr7:66124774 T/A cg26939375 chr7:64535504 NA -0.43 -6.82 -0.35 4.17e-11 Aortic root size; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg07065683 chr16:31153871 PRSS36 0.4 6.09 0.31 3.06e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs7246657 1.000 rs8110011 chr19:37745813 G/T cg23950597 chr19:37808831 NA -0.52 -6.63 -0.34 1.34e-10 Coronary artery calcification; LIHC cis rs910316 0.763 rs175057 chr14:75489632 C/T cg08847533 chr14:75593920 NEK9 -0.8 -14.91 -0.63 4.53e-39 Height; LIHC cis rs116095464 0.558 rs10080225 chr5:232175 A/G cg22857025 chr5:266934 NA -1.48 -17.96 -0.7 2.77e-51 Breast cancer; LIHC cis rs1559088 1.000 rs7245404 chr19:33550589 C/T cg27124370 chr19:33622961 WDR88 0.46 7.09 0.36 7.93e-12 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs9611565 0.592 rs5996039 chr22:41981957 A/G cg03806693 chr22:41940476 POLR3H -0.84 -9.3 -0.45 1.71e-18 Vitiligo; LIHC cis rs922107 0.738 rs2045581 chr1:90047068 T/C cg15422784 chr1:90023713 LRRC8B -0.48 -7.73 -0.39 1.19e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg25894440 chr7:65020034 NA -0.54 -6.24 -0.32 1.28e-9 Diabetic kidney disease; LIHC cis rs4474465 0.850 rs4945287 chr11:78226521 C/T cg27205649 chr11:78285834 NARS2 0.38 5.9 0.3 8.85e-9 Alzheimer's disease (survival time); LIHC cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg02990361 chr1:107599529 PRMT6 0.59 10.0 0.48 7.82e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs10876993 0.928 rs2928053 chr12:58063475 T/C cg04478727 chr12:58166393 METTL1;FAM119B -0.45 -6.32 -0.32 8.37e-10 Celiac disease or Rheumatoid arthritis; LIHC cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 8.33 0.41 1.95e-15 Platelet count; LIHC cis rs68170813 0.559 rs61406169 chr7:106903421 A/T cg02696742 chr7:106810147 HBP1 -0.53 -6.22 -0.32 1.44e-9 Coronary artery disease; LIHC cis rs7833986 0.501 rs2719255 chr8:57036658 A/G cg23139584 chr8:56987506 RPS20;SNORD54 0.85 8.58 0.42 3.31e-16 Height; LIHC cis rs17539620 0.624 rs62432735 chr6:154834055 T/C cg17771515 chr6:154831774 CNKSR3 0.58 6.14 0.31 2.35e-9 Lipoprotein (a) levels; LIHC cis rs546131 0.642 rs561477 chr11:34852152 G/A cg11058730 chr11:34937778 PDHX;APIP 0.64 9.41 0.45 7.21e-19 Lung disease severity in cystic fibrosis; LIHC cis rs1385374 0.858 rs10847696 chr12:129297153 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.66 7.91 0.39 3.51e-14 Systemic lupus erythematosus; LIHC cis rs1799949 0.602 rs8176235 chr17:41219560 C/T cg05368731 chr17:41323189 NBR1 0.65 10.31 0.49 6.98e-22 Menopause (age at onset); LIHC cis rs7833986 0.501 rs72653981 chr8:57027814 G/A cg23139584 chr8:56987506 RPS20;SNORD54 0.83 8.63 0.42 2.28e-16 Height; LIHC cis rs2836950 0.509 rs11088466 chr21:40580017 T/A cg06238570 chr21:40685208 BRWD1 -0.43 -6.93 -0.35 2.08e-11 Menarche (age at onset); LIHC cis rs8014204 0.836 rs7153700 chr14:75268544 C/T cg08847533 chr14:75593920 NEK9 0.35 5.88 0.3 9.71e-9 Caffeine consumption; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.75 12.89 0.57 2.96e-31 Prudent dietary pattern; LIHC cis rs13191362 1.000 rs73016459 chr6:163066323 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.76 6.53 0.33 2.31e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg27170947 chr2:26402098 FAM59B 0.65 8.36 0.41 1.59e-15 Gut microbiome composition (summer); LIHC cis rs5753037 0.809 rs2079338 chr22:30203842 G/A cg01021169 chr22:30184971 ASCC2 -0.36 -6.69 -0.34 9.05e-11 Type 1 diabetes; LIHC cis rs2274273 0.682 rs10145268 chr14:55504514 T/C cg01864836 chr14:55583639 NA -0.35 -5.97 -0.31 6.09e-9 Protein biomarker; LIHC trans rs1814175 0.669 rs11040473 chr11:49703813 C/T cg15704280 chr7:45808275 SEPT13 -0.69 -11.95 -0.54 9.59e-28 Height; LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg07133347 chr1:107600762 PRMT6 -0.45 -6.82 -0.35 4.03e-11 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6835098 1.000 rs6814857 chr4:174082805 T/A cg27433088 chr4:174089019 GALNT7 0.4 6.84 0.35 3.7e-11 Dementia and core Alzheimer's disease neuropathologic changes; LIHC cis rs8009147 1 rs8009147 chr14:104264662 A/G cg01849466 chr14:104193079 ZFYVE21 -0.45 -7.22 -0.36 3.33e-12 Autism spectrum disorder or schizophrenia; LIHC cis rs694739 0.894 rs12421615 chr11:64021605 G/A cg23796481 chr11:64053134 BAD;GPR137 0.53 6.3 0.32 9.23e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg11663144 chr21:46675770 NA -0.32 -5.96 -0.31 6.17e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12142240 0.698 rs7515284 chr1:46809419 A/G cg00530320 chr1:46809349 NSUN4 0.54 5.85 0.3 1.14e-8 Menopause (age at onset); LIHC cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg08280861 chr8:58055591 NA 0.53 6.61 0.34 1.48e-10 Developmental language disorder (linguistic errors); LIHC cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg21724239 chr8:58056113 NA 0.57 7.61 0.38 2.73e-13 Developmental language disorder (linguistic errors); LIHC cis rs67981189 0.656 rs2810113 chr14:71395770 C/T cg15816911 chr14:71606274 NA -0.4 -6.34 -0.32 7.19e-10 Schizophrenia; LIHC cis rs3008870 0.755 rs1570838 chr1:67403315 C/T cg02640540 chr1:67518911 SLC35D1 0.41 6.38 0.33 5.76e-10 Lymphocyte percentage of white cells; LIHC cis rs7707921 0.958 rs4703870 chr5:81492643 G/A cg15871215 chr5:81402204 ATG10 0.61 5.9 0.3 8.84e-9 Breast cancer; LIHC cis rs3008870 0.701 rs2815367 chr1:67500762 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.66 11.21 0.52 4.84e-25 Lymphocyte percentage of white cells; LIHC cis rs12971120 0.504 rs11665154 chr18:72147006 A/C cg26446133 chr18:72167187 CNDP2 -0.58 -10.18 -0.48 1.96e-21 Refractive error; LIHC trans rs61931739 0.534 rs4931775 chr12:34050729 G/A cg26384229 chr12:38710491 ALG10B 0.51 7.07 0.36 8.59e-12 Morning vs. evening chronotype; LIHC cis rs870825 0.860 rs11132253 chr4:185595472 C/T cg04058563 chr4:185651563 MLF1IP 0.61 5.74 0.3 2.05e-8 Blood protein levels; LIHC cis rs6089584 0.706 rs6089625 chr20:60620622 T/C cg13770153 chr20:60521292 NA -0.33 -6.54 -0.33 2.25e-10 Body mass index; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg15038241 chr19:48113684 GLTSCR1 -0.5 -6.79 -0.34 4.95e-11 Electroencephalogram traits; LIHC cis rs9733 0.596 rs11803569 chr1:150664077 C/T cg17724175 chr1:150552817 MCL1 0.48 9.72 0.47 7.13e-20 Tonsillectomy; LIHC cis rs7635838 0.822 rs9861633 chr3:11473437 C/G cg00170343 chr3:11313890 ATG7 0.44 6.91 0.35 2.45e-11 HDL cholesterol; LIHC cis rs2075165 1.000 rs2075165 chr1:156215899 G/A cg08469215 chr1:156261351 TMEM79 0.38 5.99 0.31 5.26e-9 Tonsillectomy; LIHC cis rs60871478 0.786 rs55899111 chr7:827843 C/G cg00934597 chr7:893267 UNC84A -0.49 -5.93 -0.31 7.27e-9 Cerebrospinal P-tau181p levels; LIHC cis rs4908760 0.965 rs10864353 chr1:8549716 A/G cg20416874 chr1:8611966 RERE -0.68 -14.36 -0.61 6.45e-37 Vitiligo; LIHC cis rs7945718 0.934 rs3993110 chr11:12794530 A/C cg25843174 chr11:12811716 TEAD1 0.3 7.05 0.36 1.01e-11 Educational attainment (years of education); LIHC cis rs2439831 0.702 rs9989313 chr15:44152817 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.63 8.84 0.43 4.99e-17 Lung cancer in ever smokers; LIHC trans rs7613875 0.620 rs34312088 chr3:50032133 C/T cg21659725 chr3:3221576 CRBN 0.55 8.25 0.41 3.57e-15 Body mass index; LIHC cis rs12497850 0.931 rs7647813 chr3:48833348 G/T cg06212747 chr3:49208901 KLHDC8B 0.57 7.42 0.37 9.22e-13 Parkinson's disease; LIHC trans rs1814175 0.587 rs7948538 chr11:50021353 A/C cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs8044995 0.501 rs73613999 chr16:68390099 C/A cg09835421 chr16:68378352 PRMT7 -0.81 -9.71 -0.46 7.77e-20 Schizophrenia; LIHC cis rs9910055 0.529 rs615070 chr17:42176591 A/G cg19774624 chr17:42201019 HDAC5 -0.49 -6.22 -0.32 1.47e-9 Total body bone mineral density; LIHC trans rs916888 0.773 rs199533 chr17:44828931 G/A cg13957321 chr17:43675089 NA 0.49 7.89 0.39 4.05e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs5769765 0.773 rs58375955 chr22:50312630 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.86 -10.38 -0.49 3.96e-22 Schizophrenia; LIHC cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg20607798 chr8:58055168 NA 0.5 6.25 0.32 1.23e-9 Developmental language disorder (linguistic errors); LIHC cis rs2777491 1.000 rs66538814 chr15:41685917 G/T cg18705301 chr15:41695430 NDUFAF1 -0.58 -8.79 -0.43 7.47e-17 Ulcerative colitis; LIHC cis rs2439831 0.850 rs3862142 chr15:44064806 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.61 8.5 0.42 6.09e-16 Lung cancer in ever smokers; LIHC cis rs9929218 1.000 rs17772363 chr16:68788909 G/T cg01231543 chr16:68741748 NA 0.38 5.89 0.3 9.14e-9 Colorectal cancer; LIHC cis rs2286885 1.000 rs1537987 chr9:129242112 T/C cg15282417 chr9:129245246 FAM125B 0.41 6.77 0.34 5.53e-11 Intraocular pressure; LIHC cis rs778371 0.958 rs778341 chr2:233728801 C/A cg08000102 chr2:233561755 GIGYF2 -0.77 -9.17 -0.44 4.53e-18 Schizophrenia; LIHC cis rs11997175 0.550 rs10954943 chr8:33815972 A/G ch.8.33884649F chr8:33765107 NA 0.4 6.73 0.34 7.31e-11 Body mass index; LIHC cis rs992157 0.735 rs10932765 chr2:219099484 T/C cg00012203 chr2:219082015 ARPC2 0.93 16.56 0.67 1.2e-45 Colorectal cancer; LIHC cis rs921968 0.643 rs659185 chr2:219335935 C/T cg18887096 chr2:219472410 PLCD4 0.38 6.74 0.34 6.94e-11 Mean corpuscular hemoglobin concentration; LIHC cis rs1552244 0.554 rs34883592 chr3:10046165 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.6 -0.38 2.87e-13 Alzheimer's disease; LIHC cis rs875971 0.895 rs778700 chr7:65866450 C/T cg11764359 chr7:65958608 NA 0.91 17.05 0.68 1.27e-47 Aortic root size; LIHC cis rs11204677 1 rs11204677 chr1:150574695 C/G cg13175981 chr1:150552382 MCL1 0.64 9.97 0.47 1.04e-20 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; LIHC trans rs8002861 0.870 rs4942254 chr13:44451820 C/T cg17145862 chr1:211918768 LPGAT1 0.6 11.29 0.52 2.42e-25 Leprosy; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg19483816 chr5:180670343 GNB2L1;SNORD95;SNORD96A 0.45 6.21 0.32 1.53e-9 Lung function (FEV1/FVC); LIHC cis rs11148252 0.904 rs9526927 chr13:53051627 C/T cg00495681 chr13:53174319 NA 0.43 7.16 0.36 5.1e-12 Lewy body disease; LIHC cis rs10861342 0.515 rs7134351 chr12:105455217 C/T cg23923672 chr12:105501055 KIAA1033 -0.45 -6.25 -0.32 1.21e-9 IgG glycosylation; LIHC trans rs1499614 1.000 rs1267818 chr7:66107024 C/T cg10756647 chr7:56101905 PSPH 1.0 11.73 0.54 6.25e-27 Gout; LIHC cis rs1816752 1.000 rs7326932 chr13:25004493 A/T cg02811702 chr13:24901961 NA 0.25 6.06 0.31 3.59e-9 Obesity-related traits; LIHC trans rs654384 0.836 rs13224986 chr7:4172109 C/T cg26675336 chr15:86133334 AKAP13 0.29 6.24 0.32 1.29e-9 Positive affect; LIHC trans rs116095464 0.558 rs2162870 chr5:228129 G/A cg00938859 chr5:1591904 SDHAP3 0.56 6.88 0.35 2.83e-11 Breast cancer; LIHC cis rs11626933 0.959 rs2149649 chr14:90774974 A/G cg04374321 chr14:90722782 PSMC1 -0.48 -6.68 -0.34 9.52e-11 Gut microbiota (bacterial taxa); LIHC cis rs922107 0.664 rs2061480 chr1:89974167 C/G cg15422784 chr1:90023713 LRRC8B 0.48 7.73 0.39 1.18e-13 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs6960043 0.738 rs2358159 chr7:15054908 T/C cg19272540 chr7:15055459 NA 0.25 6.82 0.35 4.03e-11 Type 2 diabetes; LIHC trans rs80033912 0.713 rs7629936 chr3:49836707 G/A cg21659725 chr3:3221576 CRBN 0.77 11.21 0.52 4.64e-25 Intelligence (multi-trait analysis); LIHC cis rs7249142 0.562 rs12980955 chr19:19283646 T/C cg15207422 chr19:19280969 LOC729991-MEF2B;MEF2B -0.35 -5.75 -0.3 1.95e-8 IgG glycosylation; LIHC cis rs4660306 0.961 rs12082256 chr1:45951380 A/G cg03123370 chr1:45965343 CCDC163P;MMACHC -0.64 -7.64 -0.38 2.15e-13 Homocysteine levels; LIHC cis rs7131987 0.903 rs2194519 chr12:29423583 C/T cg05697976 chr12:29376483 FAR2 -0.31 -6.41 -0.33 4.78e-10 QT interval; LIHC cis rs700651 0.789 rs1371663 chr2:198900305 C/T cg10820045 chr2:198174542 NA -0.45 -6.67 -0.34 1.01e-10 Intracranial aneurysm; LIHC cis rs3820068 0.705 rs4646091 chr1:15822043 T/C cg17385448 chr1:15911702 AGMAT 0.37 6.28 0.32 1.02e-9 Systolic blood pressure; LIHC cis rs2180341 0.814 rs9401959 chr6:127736464 T/C cg27446573 chr6:127587934 RNF146 0.79 13.09 0.58 5.05e-32 Breast cancer; LIHC cis rs933688 1.000 rs9293568 chr5:90737845 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.96 19.35 0.72 6.94e-57 Smoking behavior; LIHC trans rs1864585 0.520 rs17776946 chr8:10682674 A/C cg26278703 chr11:58910052 FAM111A 0.66 6.07 0.31 3.47e-9 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; LIHC cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg07424592 chr7:64974309 NA 0.75 8.79 0.43 7.66e-17 Diabetic kidney disease; LIHC cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg11062466 chr8:58055876 NA 0.49 7.07 0.36 8.63e-12 Developmental language disorder (linguistic errors); LIHC cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg04632378 chr13:21900426 NA 0.42 7.04 0.36 1.07e-11 Thiazide-induced adverse metabolic effects in hypertensive patients; LIHC trans rs7615952 0.800 rs35390120 chr3:125599809 G/A cg07211511 chr3:129823064 LOC729375 -0.82 -8.86 -0.43 4.39e-17 Blood pressure (smoking interaction); LIHC cis rs9790314 0.613 rs34297047 chr3:160631478 A/G cg03342759 chr3:160939853 NMD3 0.56 7.38 0.37 1.25e-12 Morning vs. evening chronotype; LIHC cis rs3008870 0.959 rs2985808 chr1:67367741 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.96 16.53 0.67 1.59e-45 Lymphocyte percentage of white cells; LIHC trans rs2739330 0.828 rs4822454 chr22:24255208 G/A cg06437703 chr8:37914619 EIF4EBP1 -0.52 -7.68 -0.38 1.68e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg18488745 chr11:67141242 LOC100130987;CLCF1 -0.42 -6.04 -0.31 4.06e-9 Calcium levels; LIHC cis rs16866061 0.515 rs1027340 chr2:225370554 C/A cg12698349 chr2:225449008 CUL3 0.89 20.81 0.75 1.05e-62 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC trans rs11148252 0.574 rs73186430 chr13:53232891 T/C cg18335740 chr13:41363409 SLC25A15 0.56 9.98 0.47 9.41e-21 Lewy body disease; LIHC cis rs748404 0.578 rs573615 chr15:43614281 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.58 9.23 0.45 2.9e-18 Lung cancer; LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10554839 chr10:27529782 ACBD5 0.43 6.77 0.34 5.49e-11 Calcium levels; LIHC cis rs743757 1.000 rs9835537 chr3:50464335 T/C cg08207895 chr3:50388901 TUSC4;CYB561D2 0.49 7.66 0.38 1.94e-13 Diastolic blood pressure; LIHC cis rs8067545 0.750 rs4570919 chr17:20000815 C/T cg13482628 chr17:19912719 NA 0.52 8.48 0.42 7.05e-16 Schizophrenia; LIHC cis rs4788570 0.625 rs2247603 chr16:71609364 G/A cg06353428 chr16:71660113 MARVELD3 -1.35 -12.22 -0.55 9.26e-29 Intelligence (multi-trait analysis); LIHC cis rs1799949 0.965 rs799910 chr17:41279561 G/C cg25072359 chr17:41440525 NA 0.4 6.39 0.33 5.53e-10 Menopause (age at onset); LIHC cis rs2073300 1.000 rs78000067 chr20:23439507 A/G cg12062639 chr20:23401060 NAPB 0.87 10.38 0.49 3.89e-22 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7208859 0.673 rs9891413 chr17:29208209 G/C cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs10078 0.515 rs6872510 chr5:481610 T/C cg07599136 chr5:415885 AHRR 0.75 12.05 0.55 4.26e-28 Fat distribution (HIV); LIHC cis rs17818399 0.788 rs17818315 chr2:46818992 C/T cg02822958 chr2:46747628 ATP6V1E2 0.44 6.72 0.34 7.41e-11 Height; LIHC cis rs6594499 0.872 rs1379298 chr5:110435726 T/C cg04022379 chr5:110408740 TSLP 0.49 8.09 0.4 1.02e-14 Allergic disease (asthma, hay fever or eczema); LIHC cis rs763121 0.853 rs5757203 chr22:39044152 G/C cg14440974 chr22:39074834 NA -0.42 -6.76 -0.34 5.83e-11 Menopause (age at onset); LIHC cis rs875971 1.000 rs6946143 chr7:65579722 A/C cg11764359 chr7:65958608 NA 0.83 14.68 0.62 3.6e-38 Aortic root size; LIHC cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg16606324 chr3:10149918 C3orf24 0.52 5.87 0.3 1.05e-8 Alzheimer's disease; LIHC cis rs763121 0.785 rs5757199 chr22:39040617 T/G cg06022373 chr22:39101656 GTPBP1 0.66 11.63 0.53 1.46e-26 Menopause (age at onset); LIHC cis rs11077998 0.844 rs12185254 chr17:80498972 C/T cg10255544 chr17:80519551 FOXK2 0.48 8.81 0.43 6.4e-17 Reticulocyte fraction of red cells; LIHC cis rs9399135 0.967 rs4896119 chr6:135293391 C/T cg24558204 chr6:135376177 HBS1L 0.41 6.76 0.34 6e-11 Red blood cell count; LIHC cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg07061783 chr6:25882402 NA 0.43 6.04 0.31 3.96e-9 Blood metabolite levels; LIHC cis rs919433 0.680 rs787983 chr2:198345797 C/T cg10820045 chr2:198174542 NA 0.51 8.37 0.41 1.44e-15 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.92 8.54 0.42 4.33e-16 Platelet count; LIHC trans rs1728785 0.901 rs1728787 chr16:68593042 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.5 0.33 2.82e-10 Ulcerative colitis; LIHC cis rs7193541 0.859 rs12598791 chr16:74500745 A/C cg01733217 chr16:74700730 RFWD3 0.5 8.54 0.42 4.52e-16 Multiple myeloma; LIHC cis rs7106204 0.748 rs11820336 chr11:24219701 G/A ch.11.24196551F chr11:24239977 NA 0.78 10.68 0.5 3.67e-23 Response to Homoharringtonine (cytotoxicity); LIHC trans rs35110281 0.714 rs2282526 chr21:45080552 A/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.5 6.66 0.34 1.08e-10 Mean corpuscular volume; LIHC cis rs17539620 0.534 rs7768635 chr6:154827861 C/T cg20019720 chr6:154832845 CNKSR3 0.48 8.15 0.4 6.75e-15 Lipoprotein (a) levels; LIHC cis rs921968 0.643 rs522377 chr2:219437476 T/C cg17980119 chr2:219472607 PLCD4 0.34 5.74 0.3 2.08e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs3770081 1.000 rs78032828 chr2:86309032 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.9 -9.91 -0.47 1.67e-20 Facial emotion recognition (sad faces); LIHC cis rs1355223 0.583 rs2941044 chr11:34867444 A/C cg11058730 chr11:34937778 PDHX;APIP 0.77 14.06 0.61 9.27e-36 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs7107174 0.892 rs1893449 chr11:77968977 G/C cg02023728 chr11:77925099 USP35 0.5 9.51 0.46 3.41e-19 Testicular germ cell tumor; LIHC cis rs951366 0.789 rs823130 chr1:205714372 C/T cg24503407 chr1:205819492 PM20D1 0.72 10.24 0.48 1.19e-21 Menarche (age at onset); LIHC cis rs11212737 0.714 rs2852186 chr11:108520640 T/G cg22776369 chr11:108536276 DDX10 0.38 6.21 0.32 1.55e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg00280220 chr17:61926910 NA 0.42 6.74 0.34 6.67e-11 Prudent dietary pattern; LIHC trans rs7939886 0.920 rs11231821 chr11:55777052 C/G cg15704280 chr7:45808275 SEPT13 0.64 6.11 0.31 2.72e-9 Myopia (pathological); LIHC cis rs34172651 0.917 rs200539 chr16:24735178 T/C cg00152838 chr16:24741724 TNRC6A 0.45 5.99 0.31 5.34e-9 Intelligence (multi-trait analysis); LIHC cis rs8067354 0.957 rs9896742 chr17:57826530 T/G cg13753209 chr17:57696993 CLTC 0.59 8.85 0.43 4.9e-17 Hemoglobin concentration; LIHC cis rs4788570 0.625 rs4788813 chr16:71625572 T/C cg06353428 chr16:71660113 MARVELD3 1.37 12.12 0.55 2.28e-28 Intelligence (multi-trait analysis); LIHC cis rs8062405 0.728 rs9931989 chr16:28906084 G/C cg07451762 chr16:28383216 NA -0.34 -6.12 -0.31 2.59e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg11062466 chr8:58055876 NA 0.5 7.36 0.37 1.39e-12 Developmental language disorder (linguistic errors); LIHC cis rs1580019 0.587 rs7806941 chr7:32553319 G/T cg06627557 chr7:32535165 LSM5;AVL9 1.15 26.36 0.82 2.34e-84 Cognitive ability; LIHC cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg19318889 chr4:1322082 MAEA 0.41 5.94 0.31 6.9e-9 Obesity-related traits; LIHC cis rs79149102 0.579 rs78664321 chr15:75339575 G/A cg16226627 chr15:75307476 SCAMP5 0.54 8.94 0.44 2.51e-17 Lung cancer; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg21745091 chr11:118992183 HINFP -0.54 -6.17 -0.32 1.94e-9 Systolic blood pressure; LIHC cis rs4819052 0.819 rs13046807 chr21:46672286 A/G cg22633049 chr21:46681294 NA -0.36 -6.18 -0.32 1.82e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg12290896 chr5:96038388 CAST 0.41 6.06 0.31 3.52e-9 Pancreatic cancer; LIHC cis rs7927771 0.864 rs11604680 chr11:47457539 A/G cg20307385 chr11:47447363 PSMC3 -0.46 -5.86 -0.3 1.1e-8 Subjective well-being; LIHC cis rs6912958 0.712 rs9444525 chr6:88324142 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.83 -0.39 6.27e-14 Monocyte percentage of white cells; LIHC cis rs7937682 0.632 rs1045282 chr11:111754574 A/C cg09085632 chr11:111637200 PPP2R1B 0.93 13.38 0.59 3.93e-33 Primary sclerosing cholangitis; LIHC cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg27094323 chr7:1216898 NA -0.4 -5.73 -0.3 2.18e-8 Longevity;Endometriosis; LIHC cis rs875971 1.000 rs6460296 chr7:65895139 C/T cg11764359 chr7:65958608 NA 0.88 15.81 0.65 1.17e-42 Aortic root size; LIHC cis rs3106136 0.934 rs4693004 chr4:95168456 G/A cg11021082 chr4:95130006 SMARCAD1 -0.44 -8.05 -0.4 1.37e-14 Capecitabine sensitivity; LIHC cis rs7095607 0.538 rs2673796 chr10:69917242 A/G cg18986048 chr10:69913749 MYPN 0.51 7.66 0.38 1.98e-13 Lung function (FVC); LIHC cis rs10847980 1.000 rs77329346 chr12:123403577 A/G cg25930673 chr12:123319894 HIP1R 0.69 6.39 0.33 5.5e-10 Adiponectin levels; LIHC cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg12310025 chr6:25882481 NA -0.65 -9.3 -0.45 1.7e-18 Blood metabolite levels; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20694715 chr12:10766273 MAGOHB 0.44 6.31 0.32 8.88e-10 Lung function (FEV1/FVC); LIHC cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg18357526 chr6:26021779 HIST1H4A 0.6 8.44 0.42 8.94e-16 Blood metabolite levels; LIHC cis rs1664789 0.836 rs702639 chr5:53267387 C/T ch.5.1024479R chr5:53302184 ARL15 0.45 6.91 0.35 2.45e-11 Waist circumference adjusted for body mass index; LIHC trans rs7395662 0.504 rs2019666 chr11:48437729 C/T cg15704280 chr7:45808275 SEPT13 -0.42 -6.44 -0.33 4.15e-10 HDL cholesterol; LIHC cis rs35306767 0.903 rs12764024 chr10:922861 A/G cg26597838 chr10:835615 NA 1.06 12.62 0.56 2.96e-30 Eosinophil percentage of granulocytes; LIHC cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg24693881 chr1:107596107 NA 0.56 9.78 0.47 4.41e-20 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs4665809 1.000 rs6546726 chr2:26275116 A/G cg04944784 chr2:26401820 FAM59B -0.66 -8.22 -0.41 4.16e-15 Gut microbiome composition (summer); LIHC cis rs870825 0.929 rs72689258 chr4:185590550 G/C cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC trans rs412658 0.776 rs12460025 chr19:22318230 A/G cg17074339 chr11:11642133 GALNTL4 -0.47 -6.97 -0.35 1.59e-11 Telomere length; LIHC cis rs801193 0.967 rs1110414 chr7:66205582 A/G cg14393609 chr7:65229607 NA 0.37 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs8114671 0.562 rs2076667 chr20:33506964 G/A cg07148914 chr20:33460835 GGT7 0.64 9.67 0.46 1.04e-19 Height; LIHC cis rs600806 0.850 rs7518013 chr1:109944078 C/T cg23091122 chr1:110024289 SYPL2 0.46 6.09 0.31 3.04e-9 Intelligence (multi-trait analysis); LIHC trans rs526821 0.595 rs517627 chr11:55356489 C/T cg03929089 chr4:120376271 NA -0.45 -6.87 -0.35 3.14e-11 Pediatric bone mineral density (spine); LIHC cis rs72627123 0.867 rs73303113 chr14:74481068 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.62 5.73 0.3 2.24e-8 Morning vs. evening chronotype; LIHC cis rs1395 0.744 rs7600932 chr2:27474869 G/A cg22903471 chr2:27725779 GCKR -0.41 -6.16 -0.32 2e-9 Blood metabolite levels; LIHC cis rs2576037 0.526 rs605487 chr18:44444778 G/C cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.67 10.56 0.5 9.43e-23 Personality dimensions; LIHC cis rs1670533 0.932 rs610218 chr4:1080083 C/G cg27284194 chr4:1044797 NA 0.6 8.92 0.43 2.8e-17 Recombination rate (females); LIHC cis rs225245 0.817 rs225284 chr17:33933006 A/C cg05299278 chr17:33885742 SLFN14 0.23 6.11 0.31 2.69e-9 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs13191362 1.000 rs13213408 chr6:162998049 A/T cg21926612 chr6:163149169 PACRG;PARK2 0.68 6.05 0.31 3.84e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7523273 0.606 rs1830764 chr1:207917052 G/A cg22525895 chr1:207977042 MIR29B2 0.66 10.7 0.5 3.06e-23 Schizophrenia; LIHC cis rs2070488 1.000 rs2268753 chr3:38500189 C/T cg24069376 chr3:38537580 EXOG 0.42 7.76 0.39 9.78e-14 Electrocardiographic conduction measures; LIHC cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg21522988 chr12:29376872 FAR2 0.29 6.48 0.33 3.21e-10 QT interval; LIHC cis rs10894294 0.589 rs7933085 chr11:130796248 A/G cg12179176 chr11:130786555 SNX19 0.6 8.72 0.43 1.27e-16 Schizophrenia; LIHC cis rs9902453 0.967 rs56326816 chr17:28492805 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.88 0.43 3.97e-17 Coffee consumption (cups per day); LIHC cis rs4631830 0.720 rs11599333 chr10:51499655 A/C cg20129853 chr10:51489980 NA 0.4 8.57 0.42 3.7e-16 Prostate-specific antigen levels; LIHC cis rs7116495 0.867 rs662649 chr11:71578875 C/T cg26138937 chr11:71823887 C11orf51 0.7 6.86 0.35 3.27e-11 Severe influenza A (H1N1) infection; LIHC cis rs34172651 0.917 rs12923476 chr16:24798079 G/A cg04756594 chr16:24857601 SLC5A11 0.47 7.41 0.37 1e-12 Intelligence (multi-trait analysis); LIHC cis rs9457247 0.967 rs2769346 chr6:167370999 A/G cg23791538 chr6:167370224 RNASET2 0.69 11.65 0.53 1.22e-26 Crohn's disease; LIHC cis rs6867032 0.958 rs4975798 chr5:2015580 G/A cg26168224 chr5:2018326 NA 0.31 7.71 0.38 1.36e-13 Gut microbiome composition (winter); LIHC trans rs17685 0.753 rs8200 chr7:75696606 C/G cg19862616 chr7:65841803 NCRNA00174 -0.92 -18.8 -0.71 1.18e-54 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs911119 0.913 rs6036463 chr20:23578940 A/T cg16589663 chr20:23618590 CST3 -0.65 -6.81 -0.35 4.51e-11 Chronic kidney disease; LIHC cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg11062466 chr8:58055876 NA 0.47 6.66 0.34 1.08e-10 Developmental language disorder (linguistic errors); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg15952933 chr7:1899886 MAD1L1 -0.4 -6.33 -0.32 7.73e-10 Calcium levels; LIHC cis rs611744 0.967 rs859788 chr8:109227570 A/G cg18478394 chr8:109455254 TTC35 0.38 6.65 0.34 1.15e-10 Dupuytren's disease; LIHC cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg25894440 chr7:65020034 NA 0.54 6.22 0.32 1.43e-9 Diabetic kidney disease; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg04164538 chr19:48867262 TMEM143;SYNGR4 -0.54 -6.07 -0.31 3.47e-9 Systolic blood pressure; LIHC cis rs9902453 0.967 rs4325622 chr17:28526475 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.56 8.72 0.43 1.26e-16 Coffee consumption (cups per day); LIHC cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.1 17.18 0.68 3.93e-48 Gut microbiome composition (summer); LIHC cis rs7662987 0.517 rs2602858 chr4:100030461 T/C cg12011299 chr4:100065546 ADH4 0.65 10.76 0.5 1.94e-23 Smoking initiation; LIHC cis rs6967414 0.681 rs2881352 chr7:6753511 T/A cg00387323 chr7:6746715 ZNF12 0.64 7.05 0.36 9.85e-12 Hematocrit;Hemoglobin concentration; LIHC cis rs35828350 1 rs35828350 chr15:85355841 G/A cg17507749 chr15:85114479 UBE2QP1 0.62 6.79 0.34 4.86e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs853679 0.517 rs4713150 chr6:28136212 G/A cg16479474 chr6:28041457 NA 0.47 6.65 0.34 1.16e-10 Depression; LIHC cis rs2439831 1.000 rs2439831 chr15:43784475 C/T cg15269541 chr15:43626905 ADAL -0.3 -5.87 -0.3 1.03e-8 Lung cancer in ever smokers; LIHC cis rs9916302 0.706 rs7208487 chr17:37543449 T/G cg07936489 chr17:37558343 FBXL20 0.86 12.17 0.55 1.45e-28 Glomerular filtration rate (creatinine); LIHC cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg23758822 chr17:41437982 NA 0.94 17.49 0.69 2.15e-49 Menopause (age at onset); LIHC cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg22963979 chr7:1858916 MAD1L1 -0.39 -6.23 -0.32 1.34e-9 Bipolar disorder and schizophrenia; LIHC cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg18252515 chr7:66147081 NA -1.25 -16.77 -0.67 1.7e-46 Diabetic kidney disease; LIHC cis rs11628318 0.614 rs7149667 chr14:103129441 G/A cg12046867 chr14:103022105 NA 0.5 7.22 0.36 3.29e-12 Platelet count; LIHC cis rs7208859 0.673 rs11080135 chr17:29176481 A/G cg14067834 chr17:29058358 SUZ12P 0.66 6.47 0.33 3.49e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2439831 1.000 rs527921 chr15:43770416 G/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.75 -11.21 -0.52 4.88e-25 Lung cancer in ever smokers; LIHC cis rs2836950 0.565 rs7278297 chr21:40625752 A/C cg11890956 chr21:40555474 PSMG1 -0.41 -6.56 -0.33 1.97e-10 Menarche (age at onset); LIHC cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg25072359 chr17:41440525 NA 0.37 5.79 0.3 1.57e-8 Menopause (age at onset); LIHC cis rs5751150 1 rs5751150 chr22:42153292 T/G cg06481639 chr22:41940642 POLR3H 0.62 5.86 0.3 1.09e-8 Cannabis dependence symptom count; LIHC cis rs9486715 0.867 rs6568428 chr6:96903604 A/G cg06623918 chr6:96969491 KIAA0776 0.84 14.52 0.62 1.44e-37 Headache; LIHC cis rs9549367 0.789 rs2287247 chr13:113889212 A/G cg18105134 chr13:113819100 PROZ -0.67 -11.63 -0.53 1.48e-26 Platelet distribution width; LIHC cis rs2274273 0.870 rs10149420 chr14:55854257 T/C cg01864836 chr14:55583639 NA -0.41 -7.51 -0.38 5.13e-13 Protein biomarker; LIHC cis rs2439831 1.000 rs2439850 chr15:43784854 C/G cg15269541 chr15:43626905 ADAL -0.3 -5.87 -0.3 1.02e-8 Lung cancer in ever smokers; LIHC cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg06873352 chr17:61820015 STRADA 0.6 9.32 0.45 1.51e-18 Height; LIHC cis rs4699052 0.787 rs2169508 chr4:104066890 T/A cg16532752 chr4:104119610 CENPE -0.43 -6.64 -0.34 1.21e-10 Testicular germ cell tumor; LIHC cis rs1023500 0.529 rs133375 chr22:42466509 C/G cg00645731 chr22:42541494 CYP2D7P1 0.39 6.08 0.31 3.21e-9 Schizophrenia; LIHC trans rs7927592 0.701 rs12226585 chr11:68257861 A/T cg00789545 chr14:102770909 RAGE 0.36 6.15 0.32 2.12e-9 Total body bone mineral density; LIHC cis rs9359856 0.636 rs6454767 chr6:90317335 G/A cg13799429 chr6:90582589 CASP8AP2 0.64 6.67 0.34 1.02e-10 Bipolar disorder; LIHC cis rs9814567 0.806 rs12637301 chr3:134317966 G/T cg06541857 chr3:134203789 ANAPC13;CEP63 -0.4 -5.74 -0.3 2.11e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs3770081 1.000 rs6705122 chr2:86176258 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -8.82 -0.43 6.02e-17 Facial emotion recognition (sad faces); LIHC trans rs6489882 0.867 rs7304898 chr12:113365667 T/C cg10175203 chr3:128143634 NA 0.39 6.37 0.33 5.94e-10 Chronic lymphocytic leukemia; LIHC cis rs748404 0.518 rs480108 chr15:43817406 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.39 5.88 0.3 9.84e-9 Lung cancer; LIHC cis rs67981189 0.613 rs4531677 chr14:71451861 A/G cg15816911 chr14:71606274 NA 0.37 5.92 0.31 7.72e-9 Schizophrenia; LIHC cis rs36051895 0.664 rs3824433 chr9:5113577 C/T cg02405213 chr9:5042618 JAK2 -0.66 -11.82 -0.54 2.79e-27 Pediatric autoimmune diseases; LIHC cis rs1862618 0.671 rs28397234 chr5:56248428 T/G cg24531977 chr5:56204891 C5orf35 0.51 7.24 0.36 2.9e-12 Initial pursuit acceleration; LIHC cis rs7582180 0.625 rs11892034 chr2:100938952 T/C cg14675211 chr2:100938903 LONRF2 0.55 8.56 0.42 4e-16 Intelligence (multi-trait analysis); LIHC cis rs7078219 0.505 rs10883371 chr10:101292455 G/T cg06854084 chr10:101292507 NKX2-3 -0.34 -6.32 -0.32 8.31e-10 Dental caries; LIHC trans rs1814175 0.645 rs28627251 chr11:50048125 G/T cg15704280 chr7:45808275 SEPT13 -0.94 -19.57 -0.73 9.79e-58 Height; LIHC cis rs7246865 0.768 rs11669463 chr19:17199314 T/C cg16202187 chr19:17186497 HAUS8;MYO9B 0.4 5.88 0.3 9.79e-9 Reticulocyte fraction of red cells; LIHC cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg13607699 chr17:42295918 UBTF -0.45 -7.26 -0.37 2.63e-12 Total body bone mineral density; LIHC cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg10712668 chr3:52740153 GLT8D1;SPCS1 0.55 7.69 0.38 1.5700000000000001e-13 Bipolar disorder; LIHC cis rs2991971 0.747 rs2492841 chr1:45894891 G/T cg05343316 chr1:45956843 TESK2 0.44 6.55 0.33 2.15e-10 High light scatter reticulocyte count; LIHC cis rs16944613 0.588 rs10852136 chr15:91139798 T/G cg26821196 chr15:91095069 CRTC3 0.44 7.23 0.36 3.1e-12 Colorectal cancer; LIHC cis rs2404602 0.692 rs35138393 chr15:76977617 G/A cg23625390 chr15:77176239 SCAPER 0.35 5.8 0.3 1.51e-8 Blood metabolite levels; LIHC cis rs9814567 1.000 rs7611611 chr3:134307877 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -12.0 -0.54 6.29e-28 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg21724239 chr8:58056113 NA 0.57 7.6 0.38 2.94e-13 Developmental language disorder (linguistic errors); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg08595667 chr16:89445453 ANKRD11 0.36 6.11 0.31 2.67e-9 Colonoscopy-negative controls vs population controls; LIHC cis rs798554 0.644 rs1639040 chr7:2884116 G/T cg04166393 chr7:2884313 GNA12 0.53 8.37 0.41 1.44e-15 Height; LIHC cis rs2224391 1.000 rs2753246 chr6:5261845 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.4 -6.09 -0.31 3.09e-9 Height; LIHC cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg11062466 chr8:58055876 NA 0.45 6.12 0.31 2.5e-9 Developmental language disorder (linguistic errors); LIHC trans rs6489882 0.867 rs7972033 chr12:113363283 C/T cg10175203 chr3:128143634 NA 0.38 6.1 0.31 2.83e-9 Chronic lymphocytic leukemia; LIHC cis rs7192750 0.586 rs2335712 chr16:71906597 A/G cg06353428 chr16:71660113 MARVELD3 -0.73 -8.18 -0.4 5.77e-15 LDL cholesterol levels;Total cholesterol levels; LIHC cis rs9517313 0.770 rs9517301 chr13:99095088 A/G cg20487152 chr13:99095054 FARP1 -0.45 -7.93 -0.39 3.16e-14 Neuroticism; LIHC trans rs4332037 0.588 rs61409925 chr7:1971226 G/A cg11693508 chr17:37793320 STARD3 0.8 8.1 0.4 9.9e-15 Bipolar disorder; LIHC cis rs2153535 0.580 rs1335643 chr6:8488021 T/G cg21535247 chr6:8435926 SLC35B3 0.6 7.92 0.39 3.48e-14 Motion sickness; LIHC cis rs12701220 0.894 rs13224488 chr7:1052353 C/A cg00990874 chr7:1149470 C7orf50 -0.69 -9.72 -0.47 7.08e-20 Bronchopulmonary dysplasia; LIHC cis rs36051895 0.632 rs11790841 chr9:5166273 G/C cg02405213 chr9:5042618 JAK2 -0.65 -9.64 -0.46 1.35e-19 Pediatric autoimmune diseases; LIHC cis rs6499255 0.951 rs7200935 chr16:69564497 T/C cg15192750 chr16:69999425 NA 0.47 7.01 0.35 1.27e-11 IgE levels; LIHC cis rs1577917 0.958 rs2084294 chr6:86565943 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.44 -8.2 -0.41 5.02e-15 Response to antipsychotic treatment; LIHC cis rs55665837 0.701 rs11023278 chr11:14641184 G/T cg19336497 chr11:14380999 RRAS2 -0.37 -6.06 -0.31 3.5e-9 Vitamin D levels; LIHC trans rs35523062 0.527 rs1387459 chr4:11911000 T/C cg26681193 chr1:6653230 KLHL21 0.38 6.2 0.32 1.64e-9 Familial hepatitis B virus-related hepatocellular carcinoma; LIHC cis rs17433710 0.543 rs4656380 chr1:162654807 C/T cg01063088 chr1:162760584 HSD17B7 0.43 5.91 0.3 8.37e-9 Dupuytren's disease; LIHC cis rs34779708 0.966 rs11599606 chr10:35406626 G/A cg03585969 chr10:35415529 CREM 0.88 13.24 0.58 1.42e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg04944784 chr2:26401820 FAM59B 0.71 9.2 0.45 3.52e-18 Gut microbiome composition (summer); LIHC cis rs9911578 0.967 rs4932693 chr17:57110327 T/C cg12560992 chr17:57184187 TRIM37 -0.98 -17.84 -0.69 8.33e-51 Intelligence (multi-trait analysis); LIHC cis rs10504073 0.647 rs1511359 chr8:50006448 T/A cg00325661 chr8:49890786 NA 0.32 7.32 0.37 1.77e-12 Blood metabolite ratios; LIHC cis rs35110281 0.632 rs9306160 chr21:45107562 T/C cg21573476 chr21:45109991 RRP1B -0.62 -11.87 -0.54 1.91e-27 Mean corpuscular volume; LIHC cis rs10744422 0.843 rs3896870 chr12:123333611 T/C cg25930673 chr12:123319894 HIP1R -0.93 -12.18 -0.55 1.35e-28 Schizophrenia; LIHC cis rs2289583 0.573 rs8025880 chr15:75394881 G/C cg15902774 chr15:75289873 SCAMP5 0.34 5.96 0.31 6.31e-9 Systemic lupus erythematosus; LIHC cis rs9473924 0.505 rs2817416 chr6:50809777 T/C cg14470998 chr6:50812995 TFAP2B 0.98 11.12 0.52 9.6e-25 Body mass index; LIHC cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.49 8.28 0.41 2.88e-15 Height; LIHC cis rs12594515 0.967 rs11856523 chr15:45989495 C/T cg19682013 chr15:45996608 NA 0.41 7.2 0.36 3.85e-12 Waist circumference;Weight; LIHC cis rs8180040 0.620 rs11917361 chr3:47070497 G/T cg16586182 chr3:47516702 SCAP 0.47 8.7 0.43 1.43e-16 Colorectal cancer; LIHC cis rs10056811 0.527 rs55798253 chr5:74380957 A/G cg19683494 chr5:74908142 NA 0.7 7.73 0.39 1.21e-13 Coronary artery disease; LIHC cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg22907277 chr7:1156413 C7orf50 0.53 8.19 0.41 5.12e-15 Longevity;Endometriosis; LIHC trans rs875971 0.545 rs7810213 chr7:65946579 G/C cg26939375 chr7:64535504 NA 0.41 6.49 0.33 2.98e-10 Aortic root size; LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg26338869 chr17:61819248 STRADA 0.59 8.66 0.42 1.96e-16 Prudent dietary pattern; LIHC cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg21724239 chr8:58056113 NA 0.59 7.46 0.37 7e-13 Developmental language disorder (linguistic errors); LIHC cis rs1534166 0.647 rs7355929 chr3:133514190 C/T cg27366882 chr3:133540807 NA -0.42 -7.23 -0.36 3.28e-12 Alcohol consumption (transferrin glycosylation); LIHC cis rs7772486 0.521 rs9485017 chr6:146023326 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -8.27 -0.41 3e-15 Lobe attachment (rater-scored or self-reported); LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg06362048 chr16:15051589 NA -0.45 -6.72 -0.34 7.6e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs35883536 0.609 rs2647327 chr1:101041766 C/T cg14515779 chr1:101123966 NA -0.43 -6.01 -0.31 4.8e-9 Monocyte count; LIHC cis rs9341808 0.754 rs9341810 chr6:80974838 G/A cg08355045 chr6:80787529 NA 0.35 7.34 0.37 1.55e-12 Sitting height ratio; LIHC cis rs7582720 1.000 rs72926783 chr2:203815740 T/A cg15057621 chr2:203777863 WDR12;ALS2CR8 0.77 6.37 0.33 6.24e-10 Coronary artery disease or ischemic stroke;Coronary artery disease or large artery stroke; LIHC cis rs1046896 0.552 rs12602280 chr17:80805421 G/C cg02711726 chr17:80685570 FN3KRP -0.44 -8.02 -0.4 1.68e-14 Glycated hemoglobin levels; LIHC cis rs7843479 1.000 rs1032094 chr8:21820479 A/T cg17168535 chr8:21777572 XPO7 0.42 6.47 0.33 3.36e-10 Mean corpuscular volume; LIHC cis rs17253792 0.822 rs79262019 chr14:56092704 A/G cg01858014 chr14:56050164 KTN1 -0.76 -7.96 -0.4 2.64e-14 Putamen volume; LIHC cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg07677032 chr17:61819896 STRADA 0.43 6.25 0.32 1.23e-9 Prudent dietary pattern; LIHC cis rs8062405 1.000 rs7198606 chr16:28875122 T/G cg00204512 chr16:28754710 NA 0.34 6.27 0.32 1.07e-9 Cognitive ability (multi-trait analysis);Cognitive ability; LIHC cis rs9649465 1.000 rs10270877 chr7:123327860 T/C cg03229431 chr7:123269106 ASB15 -0.38 -8.18 -0.4 5.61e-15 Migraine; LIHC cis rs1865760 0.686 rs12210098 chr6:25963966 C/T cg17691542 chr6:26056736 HIST1H1C 0.46 5.87 0.3 1.06e-8 Height; LIHC cis rs7116495 0.786 rs1892919 chr11:71712175 G/A cg26138937 chr11:71823887 C11orf51 -0.77 -7.87 -0.39 4.81e-14 Severe influenza A (H1N1) infection; LIHC cis rs9322193 0.607 rs9371228 chr6:150243113 G/A cg01145232 chr6:150245071 RAET1G -0.43 -8.11 -0.4 9.35e-15 Lung cancer; LIHC cis rs3020736 0.519 rs5996116 chr22:42517492 G/A cg15557168 chr22:42548783 NA 0.43 6.79 0.34 4.89e-11 Autism spectrum disorder or schizophrenia; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg04364504 chr16:58035198 C16orf57;ZNF319 0.48 6.55 0.33 2.08e-10 Lung function (FEV1/FVC); LIHC cis rs798554 0.757 rs2644312 chr7:2841164 G/A cg19346786 chr7:2764209 NA -0.46 -6.93 -0.35 2.11e-11 Height; LIHC trans rs1814175 0.616 rs1851848 chr11:49992254 G/C cg15704280 chr7:45808275 SEPT13 -0.96 -20.04 -0.73 1.23e-59 Height; LIHC trans rs3780486 0.718 rs10971418 chr9:33122024 A/C cg20290983 chr6:43655470 MRPS18A -0.96 -14.45 -0.62 2.82e-37 IgG glycosylation; LIHC cis rs79057730 0.599 rs34411410 chr7:811721 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.85 9.65 0.46 1.23e-19 Initial pursuit acceleration; LIHC cis rs9640161 0.830 rs35635199 chr7:150063342 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.03 -0.4 1.64e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs7598759 0.548 rs11686485 chr2:232360697 C/T cg19187155 chr2:232395269 NMUR1 0.56 8.71 0.43 1.29e-16 Noise-induced hearing loss; LIHC cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg10802521 chr3:52805072 NEK4 -0.44 -7.61 -0.38 2.72e-13 Bipolar disorder; LIHC cis rs11690935 0.885 rs6725388 chr2:172730015 G/C cg13550731 chr2:172543902 DYNC1I2 -0.81 -14.76 -0.62 1.79e-38 Schizophrenia; LIHC cis rs6754311 0.731 rs3754686 chr2:136603276 T/C cg07305463 chr2:136567211 LCT 0.38 7.37 0.37 1.25e-12 Mosquito bite size; LIHC cis rs17685 0.753 rs2286830 chr7:75693963 C/T cg16684958 chr7:75615977 POR -0.52 -8.79 -0.43 7.28e-17 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2257205 0.667 rs7217890 chr17:56731265 G/A cg05425664 chr17:57184151 TRIM37 -0.6 -6.58 -0.34 1.76e-10 Pancreatic cancer; LIHC cis rs3748682 0.861 rs12563037 chr1:38258644 C/G cg12658694 chr1:38397304 INPP5B -0.43 -6.12 -0.31 2.49e-9 Hypothyroidism; LIHC trans rs1005277 0.579 rs2505198 chr10:38393183 A/C cg23533926 chr12:111358616 MYL2 -0.33 -6.37 -0.33 6.02e-10 Extrinsic epigenetic age acceleration; LIHC cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg06873352 chr17:61820015 STRADA 0.75 13.58 0.59 6.97e-34 Prudent dietary pattern; LIHC cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg21724239 chr8:58056113 NA 0.48 6.41 0.33 4.88e-10 Developmental language disorder (linguistic errors); LIHC cis rs1799949 1.000 rs915945 chr17:41179864 C/T cg05368731 chr17:41323189 NBR1 0.74 12.61 0.56 3.45e-30 Menopause (age at onset); LIHC cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.39 5.73 0.3 2.21e-8 Menopause (age at onset); LIHC cis rs79149102 0.579 rs61166993 chr15:75306644 C/A cg15902774 chr15:75289873 SCAMP5 0.39 6.07 0.31 3.36e-9 Lung cancer; LIHC cis rs7917772 0.582 rs10786684 chr10:104323028 A/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -8.03 -0.4 1.61e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs9818758 0.607 rs11706052 chr3:49064110 A/G cg00383909 chr3:49044727 WDR6 0.85 7.04 0.36 1.09e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; LIHC cis rs11792861 0.926 rs118011482 chr9:111770626 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.63 8.76 0.43 9.2e-17 Menarche (age at onset); LIHC cis rs61990749 0.597 rs7142390 chr14:78232880 T/C cg21497246 chr14:78225524 SNW1;C14orf178 -0.52 -7.79 -0.39 8.26e-14 Fibroblast growth factor basic levels; LIHC cis rs2204008 0.583 rs12820907 chr12:37990931 T/C cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs3020736 0.500 rs6002614 chr22:42501802 G/A cg15557168 chr22:42548783 NA 0.43 6.77 0.34 5.56e-11 Autism spectrum disorder or schizophrenia; LIHC cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg03264133 chr6:25882463 NA -0.54 -6.62 -0.34 1.41e-10 Intelligence (multi-trait analysis); LIHC cis rs425277 0.958 rs262660 chr1:2086757 A/G cg24578937 chr1:2090814 PRKCZ 0.5 9.05 0.44 1.07e-17 Height; LIHC cis rs11711311 0.955 rs1048892 chr3:113464859 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.49 9.47 0.46 4.58e-19 IgG glycosylation; LIHC trans rs10411161 0.579 rs59305384 chr19:52387064 A/G cg22319618 chr22:45562946 NUP50 -0.61 -8.37 -0.41 1.47e-15 Breast cancer; LIHC cis rs4979906 1.000 rs11002242 chr10:79445873 G/C cg07817648 chr10:79422355 NA -0.28 -6.05 -0.31 3.8e-9 Mortality in heart failure; LIHC cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg18404041 chr3:52824283 ITIH1 -0.57 -9.51 -0.46 3.48e-19 Intelligence (multi-trait analysis); LIHC cis rs6088580 0.524 rs7274854 chr20:33228672 A/C cg08999081 chr20:33150536 PIGU 0.44 7.85 0.39 5.29e-14 Glomerular filtration rate (creatinine); LIHC cis rs798554 0.731 rs2283779 chr7:2815140 G/A cg19717773 chr7:2847554 GNA12 -0.41 -7.29 -0.37 2.2e-12 Height; LIHC cis rs3736485 0.934 rs4143723 chr15:51867172 A/G cg08986416 chr15:51914746 DMXL2 -0.42 -6.28 -0.32 1e-9 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg02290350 chr8:58132656 NA -0.55 -10.53 -0.49 1.26e-22 Developmental language disorder (linguistic errors); LIHC cis rs7927592 0.956 rs6591341 chr11:68335478 C/T cg20283391 chr11:68216788 NA -0.53 -8.06 -0.4 1.33e-14 Total body bone mineral density; LIHC cis rs6748734 1.000 rs6748734 chr2:241837452 A/G cg08694578 chr2:241835147 C2orf54 -0.51 -6.91 -0.35 2.39e-11 Urinary metabolites; LIHC cis rs929354 0.772 rs1002389 chr7:156968323 C/G cg16102536 chr7:156981717 UBE3C 0.34 5.77 0.3 1.75e-8 Body mass index; LIHC cis rs2997447 0.761 rs72886625 chr1:26455319 A/G cg19633962 chr1:26362018 EXTL1 -0.65 -5.76 -0.3 1.87e-8 QRS complex (12-leadsum); LIHC cis rs780096 0.506 rs2288155 chr2:27714526 T/C cg27432699 chr2:27873401 GPN1 -0.56 -8.04 -0.4 1.5e-14 Total body bone mineral density; LIHC cis rs2840044 1.000 rs10068 chr17:33901965 C/G cg20932281 chr17:33905541 PEX12 0.42 5.76 0.3 1.9e-8 Response to radiotherapy in cancer (late toxicity); LIHC cis rs769267 0.930 rs10402451 chr19:19608537 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.52 7.98 0.4 2.19e-14 Tonsillectomy; LIHC cis rs6089584 0.528 rs881994 chr20:60623931 G/A cg13770153 chr20:60521292 NA -0.3 -5.75 -0.3 1.95e-8 Body mass index; LIHC cis rs2576037 0.501 rs7227700 chr18:44537102 T/G cg07416455 chr18:44543612 TCEB3CL;KATNAL2 -0.48 -7.15 -0.36 5.32e-12 Personality dimensions; LIHC cis rs2180341 0.960 rs9398840 chr6:127669744 G/A cg27446573 chr6:127587934 RNF146 1.06 16.62 0.67 6.67e-46 Breast cancer; LIHC cis rs7589728 0.514 rs74426843 chr2:88459388 C/T cg07952391 chr2:88470173 THNSL2 0.79 7.52 0.38 4.77e-13 Plasma clusterin levels; LIHC cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.86 0.39 5.2e-14 Prudent dietary pattern; LIHC cis rs6430585 0.583 rs4988145 chr2:136632300 A/C cg07169764 chr2:136633963 MCM6 1.34 23.39 0.78 6.41e-73 Corneal structure; LIHC cis rs751728 1.000 rs6904991 chr6:33732262 T/G cg25922239 chr6:33757077 LEMD2 0.46 7.61 0.38 2.62e-13 Crohn's disease; LIHC cis rs1707322 0.964 rs7512395 chr1:46361177 G/A cg06784218 chr1:46089804 CCDC17 0.37 6.34 0.32 7.16e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs1973993 0.691 rs1980683 chr1:96890379 A/G cg10631902 chr5:14652156 NA 0.35 9.46 0.46 5.21e-19 Weight; LIHC cis rs12144094 0.766 rs74984954 chr1:120234068 G/A cg20995928 chr1:120229863 NA 0.38 6.31 0.32 8.74e-10 Height; LIHC cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg15691649 chr6:25882328 NA -0.41 -6.4 -0.33 5.2e-10 Height; LIHC cis rs9399135 0.933 rs4559100 chr6:135324085 T/C cg22676075 chr6:135203613 NA 0.38 6.29 0.32 9.78e-10 Red blood cell count; LIHC cis rs1371867 0.726 rs1660333 chr8:101309989 A/G cg06636551 chr8:101224915 SPAG1 -0.45 -8.78 -0.43 8.25e-17 Atrioventricular conduction; LIHC cis rs798766 1.000 rs2305188 chr4:1739592 A/G cg21231739 chr4:1642635 FAM53A -0.37 -6.0 -0.31 5.06e-9 Bladder cancer;Urinary bladder cancer; LIHC cis rs3770081 0.590 rs6747424 chr2:86176224 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -0.77 -8.82 -0.43 6.02e-17 Facial emotion recognition (sad faces); LIHC cis rs2070488 0.965 rs9829192 chr3:38569463 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -14.5 -0.62 1.78e-37 Electrocardiographic conduction measures; LIHC trans rs5756813 0.754 rs15691 chr22:38172380 C/A cg19894588 chr14:64061835 NA -0.66 -9.1 -0.44 7.89e-18 Optic cup area;Vertical cup-disc ratio; LIHC cis rs875971 0.862 rs7782704 chr7:65805366 G/A cg11764359 chr7:65958608 NA -0.85 -15.2 -0.64 3.07e-40 Aortic root size; LIHC cis rs1552244 0.554 rs6796411 chr3:10010681 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.58 8.14 0.4 7.62e-15 Alzheimer's disease; LIHC cis rs1215050 0.755 rs783958 chr4:98893836 A/T cg05340658 chr4:99064831 C4orf37 -0.39 -5.79 -0.3 1.58e-8 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs4803468 0.967 rs11670583 chr19:41920440 A/T cg09537434 chr19:41945824 ATP5SL -1.02 -21.69 -0.76 3.18e-66 Height; LIHC cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg22618164 chr12:122356400 WDR66 0.56 8.48 0.42 6.83e-16 Mean corpuscular volume; LIHC cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg11905131 chr22:24372483 LOC391322 -0.78 -12.31 -0.55 4.54e-29 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs9828933 0.701 rs7621544 chr3:63928681 C/A cg16258503 chr3:63850278 ATXN7;THOC7 -0.69 -8.94 -0.44 2.49e-17 Type 2 diabetes; LIHC cis rs3820068 0.603 rs72647128 chr1:15963908 T/C cg17385448 chr1:15911702 AGMAT 0.33 5.8 0.3 1.53e-8 Systolic blood pressure; LIHC cis rs10508774 0.810 rs72793585 chr10:32730431 C/T cg01819863 chr10:32635814 EPC1 0.61 5.88 0.3 9.61e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs6952808 0.756 rs12537348 chr7:1948172 C/G cg04267008 chr7:1944627 MAD1L1 -0.73 -11.7 -0.53 8.11e-27 Bipolar disorder and schizophrenia; LIHC trans rs12752401 1.000 rs67551785 chr1:102978472 T/C cg03332897 chr19:740442 PALM 0.46 6.14 0.32 2.23e-9 Resistance to antihypertensive treatment in hypertension; LIHC cis rs5997397 0.967 rs5752791 chr22:29153547 A/G cg02153584 chr22:29168773 CCDC117 -0.45 -6.92 -0.35 2.18e-11 Red cell distribution width; LIHC cis rs2050392 0.624 rs2489842 chr10:30721991 T/C cg25182066 chr10:30743637 MAP3K8 -0.62 -9.87 -0.47 2.17e-20 Inflammatory bowel disease; LIHC cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg15691649 chr6:25882328 NA -0.6 -8.02 -0.4 1.65e-14 Intelligence (multi-trait analysis); LIHC cis rs780096 0.506 rs1647286 chr2:27714517 A/T cg11618577 chr2:27665543 KRTCAP3 -0.44 -5.97 -0.31 5.81e-9 Total body bone mineral density; LIHC cis rs7639513 0.737 rs13070228 chr3:12706914 G/A cg23032965 chr3:12705835 RAF1 0.65 7.85 0.39 5.27e-14 Itch intensity from mosquito bite; LIHC cis rs1707322 0.721 rs4609469 chr1:46117185 C/T cg06784218 chr1:46089804 CCDC17 0.41 7.76 0.39 9.66e-14 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1215050 0.740 rs2695464 chr4:98980929 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -6.35 -0.32 6.67e-10 Waist-to-hip ratio adjusted for body mass index; LIHC trans rs1005277 0.505 rs7069702 chr10:38247359 G/T cg17830980 chr10:43048298 ZNF37B 0.46 8.96 0.44 2.13e-17 Extrinsic epigenetic age acceleration; LIHC cis rs1707322 0.752 rs6703748 chr1:46095976 G/A cg03146154 chr1:46216737 IPP 0.55 9.14 0.44 5.73e-18 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs9902453 0.874 rs7220004 chr17:28369548 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.79 -13.84 -0.6 6.53e-35 Coffee consumption (cups per day); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg10965738 chr5:39071344 RICTOR -0.26 -6.28 -0.32 1.01e-9 Calcium levels; LIHC cis rs903552 1.000 rs12908406 chr15:102004046 C/T cg19295451 chr15:102010161 PCSK6 -0.48 -6.73 -0.34 7.33e-11 Diabetic kidney disease; LIHC cis rs1005277 0.579 rs1780133 chr10:38499509 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.11 -0.44 7e-18 Extrinsic epigenetic age acceleration; LIHC trans rs6934970 1.000 rs2347031 chr6:113016262 A/G cg09308777 chr6:169852575 NA 0.6 6.21 0.32 1.5e-9 Bipolar disorder (body mass index interaction); LIHC cis rs6500602 0.702 rs56895104 chr16:4548132 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.38 5.76 0.3 1.89e-8 Schizophrenia; LIHC cis rs9379850 0.528 rs67575965 chr6:26196593 A/G cg03854865 chr6:26224070 HIST1H3E 0.54 6.66 0.34 1.08e-10 Intelligence (multi-trait analysis); LIHC cis rs2637266 0.627 rs2013238 chr10:78476272 A/C cg18941641 chr10:78392320 NA 0.28 6.2 0.32 1.61e-9 Pulmonary function; LIHC cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg18230493 chr5:56204884 C5orf35 -0.47 -6.6 -0.34 1.58e-10 Initial pursuit acceleration; LIHC trans rs10197140 0.857 rs10175204 chr2:111643355 C/T cg23556447 chr6:90529595 MDN1 -0.39 -6.33 -0.32 7.76e-10 Mean corpuscular hemoglobin;Mean corpuscular volume;Red blood cell count; LIHC cis rs36051895 0.560 rs1575281 chr9:5219131 T/C cg02405213 chr9:5042618 JAK2 -0.61 -9.6 -0.46 1.74e-19 Pediatric autoimmune diseases; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13319049 chr4:39699555 UBE2K 0.44 6.51 0.33 2.74e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11758351 0.929 rs75475698 chr6:26190609 C/G cg03854865 chr6:26224070 HIST1H3E 0.64 7.14 0.36 5.78e-12 Gout;Renal underexcretion gout; LIHC cis rs1862618 0.671 rs2591958 chr5:56239369 C/G cg24531977 chr5:56204891 C5orf35 0.52 7.67 0.38 1.77e-13 Initial pursuit acceleration; LIHC cis rs9814567 0.806 rs9839705 chr3:134323819 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.4 -0.45 7.89e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs8177253 0.555 rs4481157 chr3:133464684 G/A cg16262614 chr3:133464971 TF 0.32 7.22 0.36 3.36e-12 Iron status biomarkers; LIHC trans rs9929218 1.000 rs28660361 chr16:68800838 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -8.75 -0.43 1.01e-16 Colorectal cancer; LIHC cis rs1461503 0.934 rs11605693 chr11:122837037 T/C cg25161029 chr11:122845972 NA 0.38 6.4 0.33 5.17e-10 Menarche (age at onset); LIHC cis rs16958440 0.867 rs74845165 chr18:44690852 T/C cg17192377 chr18:44677553 HDHD2 0.92 8.72 0.43 1.22e-16 Sitting height ratio; LIHC cis rs4819052 0.851 rs2838840 chr21:46668494 A/G cg11663144 chr21:46675770 NA -0.32 -5.93 -0.31 7.55e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC trans rs7246657 0.943 rs10403613 chr19:37844306 C/T cg10208301 chr11:6592745 DNHD1 0.48 6.48 0.33 3.25e-10 Coronary artery calcification; LIHC cis rs11958404 0.860 rs7723564 chr5:157449396 C/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs250677 0.652 rs36045 chr5:148441184 A/G cg18129178 chr5:148520854 ABLIM3 0.53 6.89 0.35 2.71e-11 Breast cancer; LIHC cis rs12594515 1.000 rs8026221 chr15:45987910 G/T cg01629716 chr15:45996671 NA 0.52 9.5 0.46 3.84e-19 Waist circumference;Weight; LIHC cis rs1552244 0.882 rs13064570 chr3:9997545 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.61 -8.92 -0.43 2.78e-17 Alzheimer's disease; LIHC cis rs523522 0.962 rs4766969 chr12:120988238 A/G cg27279351 chr12:120934652 DYNLL1 0.67 11.98 0.54 7.42e-28 High light scatter reticulocyte count; LIHC cis rs7617773 0.823 rs9839446 chr3:48194666 T/A cg11946769 chr3:48343235 NME6 -0.65 -8.3 -0.41 2.51e-15 Coronary artery disease; LIHC trans rs7615952 0.741 rs13314845 chr3:125644782 C/T cg07211511 chr3:129823064 LOC729375 -0.85 -10.5 -0.49 1.57e-22 Blood pressure (smoking interaction); LIHC cis rs4589502 0.557 rs7495093 chr15:67155221 T/C cg12317470 chr15:67143691 NA 0.51 5.92 0.31 7.72e-9 Lung cancer (smoking interaction); LIHC cis rs66573146 0.572 rs55740475 chr4:6954092 C/G cg00086871 chr4:6988644 TBC1D14 0.8 6.06 0.31 3.61e-9 Granulocyte percentage of myeloid white cells; LIHC cis rs10197940 0.578 rs1061305 chr2:152346979 T/C cg19508488 chr2:152266495 RIF1 0.47 6.68 0.34 9.96e-11 Lung cancer; LIHC cis rs1046896 0.594 rs67813226 chr17:80851134 G/A cg02711726 chr17:80685570 FN3KRP -0.41 -7.16 -0.36 4.98e-12 Glycated hemoglobin levels; LIHC cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs9303401 1.000 rs7218362 chr17:56888299 A/G cg12560992 chr17:57184187 TRIM37 0.73 10.83 0.51 1.08e-23 Cognitive test performance; LIHC cis rs2625529 0.761 rs3743224 chr15:72466799 C/T cg16672083 chr15:72433130 SENP8 -0.31 -5.86 -0.3 1.06e-8 Red blood cell count; LIHC cis rs11098499 0.955 rs35916640 chr4:120155852 T/C cg09307838 chr4:120376055 NA 0.75 10.9 0.51 6e-24 Corneal astigmatism; LIHC cis rs72781680 0.665 rs2675356 chr2:24074734 C/T cg08917208 chr2:24149416 ATAD2B 0.62 6.44 0.33 4.09e-10 Lymphocyte counts; LIHC trans rs875971 0.545 rs10261710 chr7:65714189 T/A cg26939375 chr7:64535504 NA 0.44 6.9 0.35 2.59e-11 Aortic root size; LIHC cis rs700651 0.789 rs1978889 chr2:198889366 G/A cg03934865 chr2:198174659 NA 0.43 6.2 0.32 1.62e-9 Intracranial aneurysm; LIHC cis rs9640161 0.830 rs35840727 chr7:150063204 A/G cg21361702 chr7:150065534 REPIN1 0.54 7.46 0.37 7.19e-13 Blood protein levels;Circulating chemerin levels; LIHC cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg11070056 chr1:107600091 PRMT6 0.69 11.92 0.54 1.26e-27 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs523522 0.962 rs10849759 chr12:120994488 T/A cg12219531 chr12:120966889 COQ5 0.68 13.61 0.59 5.27e-34 High light scatter reticulocyte count; LIHC cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg01017244 chr2:74357527 NA 0.51 8.76 0.43 8.88e-17 Gestational age at birth (maternal effect); LIHC cis rs734999 0.505 rs4073285 chr1:2539796 C/T cg18854424 chr1:2615690 NA 0.32 7.05 0.36 9.66e-12 Ulcerative colitis; LIHC cis rs986417 0.606 rs4899014 chr14:61118783 C/T cg27398547 chr14:60952738 C14orf39 0.59 6.51 0.33 2.7e-10 Gut microbiota (bacterial taxa); LIHC cis rs2153535 0.580 rs1119690 chr6:8460660 G/A cg21535247 chr6:8435926 SLC35B3 0.64 8.35 0.41 1.77e-15 Motion sickness; LIHC cis rs769267 0.825 rs1469713 chr19:19528806 A/G cg15052019 chr19:19431593 KIAA0892;SF4 0.43 5.95 0.31 6.81e-9 Tonsillectomy; LIHC cis rs8072100 0.967 rs12452315 chr17:45479446 G/T cg25173405 chr17:45401733 C17orf57 0.42 5.96 0.31 6.31e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); LIHC trans rs7666738 0.606 rs4699606 chr4:99095074 A/C cg05439608 chr7:156761192 NOM1 0.4 6.98 0.35 1.55e-11 Colonoscopy-negative controls vs population controls; LIHC cis rs9326248 1.000 rs7107152 chr11:117056080 C/T cg10130564 chr11:117069849 TAGLN -0.36 -6.05 -0.31 3.82e-9 Blood protein levels; LIHC cis rs801193 0.660 rs974239 chr7:66213491 G/A cg11764359 chr7:65958608 NA 0.83 14.66 0.62 4.37e-38 Aortic root size; LIHC cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg18306943 chr3:40428807 ENTPD3 0.42 7.38 0.37 1.21e-12 Renal cell carcinoma; LIHC cis rs7914558 1.000 rs10883824 chr10:104812897 A/G cg15744005 chr10:104629667 AS3MT -0.37 -8.17 -0.4 6.14e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs244293 0.899 rs8080876 chr17:53175267 T/C cg19360675 chr17:53046073 COX11;STXBP4 0.49 7.27 0.37 2.5e-12 Menarche (age at onset); LIHC cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg07677032 chr17:61819896 STRADA 0.44 6.36 0.33 6.38e-10 Prudent dietary pattern; LIHC cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg11494091 chr17:61959527 GH2 0.52 10.14 0.48 2.69e-21 Prudent dietary pattern; LIHC cis rs80282103 0.618 rs10794720 chr10:1156165 A/G cg08668510 chr10:1095578 IDI1 -0.69 -7.37 -0.37 1.31e-12 Glomerular filtration rate (creatinine); LIHC cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg11764359 chr7:65958608 NA 0.59 6.04 0.31 3.97e-9 Diabetic kidney disease; LIHC cis rs9467773 1.000 rs9357010 chr6:26527945 C/G cg09904177 chr6:26538194 HMGN4 0.65 13.69 0.59 2.57e-34 Intelligence (multi-trait analysis); LIHC cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg20090690 chr10:134436459 INPP5A 0.45 5.78 0.3 1.72e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs11628318 0.614 rs942022 chr14:103108842 C/T cg12046867 chr14:103022105 NA -0.52 -7.53 -0.38 4.44e-13 Platelet count; LIHC cis rs3824867 0.920 rs7126210 chr11:47460306 A/G cg20307385 chr11:47447363 PSMC3 0.57 7.66 0.38 1.92e-13 Mean corpuscular hemoglobin; LIHC cis rs9926296 0.585 rs8058009 chr16:89856439 G/C cg03809021 chr16:89831123 FANCA 0.94 10.0 0.48 8.29e-21 Vitiligo; LIHC cis rs17001868 0.568 rs17001846 chr22:40744053 A/G cg07138101 chr22:40742427 ADSL 0.54 6.41 0.33 4.96e-10 Mammographic density (dense area); LIHC cis rs9790314 1.000 rs336589 chr3:161080358 C/T cg04691961 chr3:161091175 C3orf57 -0.46 -7.4 -0.37 1.06e-12 Morning vs. evening chronotype; LIHC cis rs4700695 0.925 rs381549 chr5:65383371 A/G cg21114390 chr5:65439923 SFRS12 -0.46 -6.02 -0.31 4.39e-9 Facial morphology (factor 19); LIHC cis rs4319547 0.656 rs9788145 chr12:122899522 C/T cg05707623 chr12:122985044 ZCCHC8 -0.55 -7.31 -0.37 1.92e-12 Body mass index; LIHC cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg03351412 chr1:154909251 PMVK 0.7 10.46 0.49 2.17e-22 Prostate cancer; LIHC cis rs8044995 0.563 rs3743743 chr16:68397775 C/T cg05110241 chr16:68378359 PRMT7 -0.86 -9.64 -0.46 1.34e-19 Schizophrenia; LIHC cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg03517284 chr6:25882590 NA -0.62 -8.79 -0.43 7.18e-17 Blood metabolite levels; LIHC cis rs80282103 0.867 rs74117668 chr10:1076620 C/T cg08668510 chr10:1095578 IDI1 0.65 6.63 0.34 1.28e-10 Glomerular filtration rate (creatinine); LIHC cis rs13202913 0.837 rs6906678 chr6:151772395 A/T cg10883421 chr6:151773342 RMND1;C6orf211 0.54 6.97 0.35 1.66e-11 Epstein-Barr virus copy number in lymphoblastoid cell lines; LIHC cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg24642844 chr7:1081250 C7orf50 -0.86 -8.75 -0.43 1.01e-16 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC trans rs561341 1.000 rs542132 chr17:30307193 A/T cg20587970 chr11:113659929 NA -1.38 -11.71 -0.53 7.6e-27 Hip circumference adjusted for BMI; LIHC cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg18306943 chr3:40428807 ENTPD3 0.42 7.43 0.37 8.93e-13 Renal cell carcinoma; LIHC cis rs11779988 0.545 rs439374 chr8:17786818 C/T cg01800426 chr8:17659068 MTUS1 -0.4 -5.86 -0.3 1.11e-8 Breast cancer; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg16515820 chr3:114866447 ZBTB20 0.52 7.53 0.38 4.46e-13 Pancreatic cancer; LIHC cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.12 -0.31 2.52e-9 Total body bone mineral density; LIHC cis rs600806 0.778 rs11101962 chr1:110014187 A/T cg08911820 chr1:110026001 ATXN7L2 -0.58 -7.38 -0.37 1.18e-12 Intelligence (multi-trait analysis); LIHC cis rs28489187 0.706 rs1498375 chr1:85787323 T/A cg16011679 chr1:85725395 C1orf52 0.48 6.14 0.31 2.35e-9 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); LIHC cis rs36051895 0.659 rs11999076 chr9:5037694 C/T cg02405213 chr9:5042618 JAK2 -0.73 -13.24 -0.58 1.42e-32 Pediatric autoimmune diseases; LIHC cis rs921968 0.541 rs10205073 chr2:219412784 C/A cg02176678 chr2:219576539 TTLL4 -0.55 -7.7 -0.38 1.5e-13 Mean corpuscular hemoglobin concentration; LIHC cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg26116260 chr4:7069785 GRPEL1 1.0 18.4 0.71 4.69e-53 Monocyte percentage of white cells; LIHC cis rs561341 1.000 rs473356 chr17:30321762 G/C cg00745463 chr17:30367425 LRRC37B -0.77 -5.73 -0.3 2.16e-8 Hip circumference adjusted for BMI; LIHC cis rs7044106 0.734 rs12553070 chr9:123485266 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.76 12.51 0.56 7.73e-30 Hip circumference adjusted for BMI; LIHC cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC trans rs7714584 1.000 rs13361189 chr5:150223387 A/G cg20675040 chr8:143813288 C8orf55 0.36 6.29 0.32 9.88e-10 Crohn's disease; LIHC cis rs870825 0.616 rs4594761 chr4:185643002 A/C cg04058563 chr4:185651563 MLF1IP 0.71 7.47 0.37 6.89e-13 Blood protein levels; LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg02674305 chr20:34359915 PHF20 0.37 6.09 0.31 3.07e-9 Bilirubin levels; LIHC cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 9.34 0.45 1.31e-18 Bipolar disorder; LIHC cis rs6690583 0.623 rs61770879 chr1:85504938 A/C cg22153463 chr1:85462885 MCOLN2 0.49 5.87 0.3 1.03e-8 Serum sulfate level; LIHC cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg11301795 chr4:187892539 NA -0.26 -7.04 -0.36 1.04e-11 Lobe attachment (rater-scored or self-reported); LIHC cis rs4950322 0.576 rs2353979 chr1:146839900 A/G cg25205988 chr1:146714368 CHD1L 0.44 6.16 0.32 1.99e-9 Protein quantitative trait loci; LIHC cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg22105103 chr4:187893119 NA 0.34 8.48 0.42 7.07e-16 Lobe attachment (rater-scored or self-reported); LIHC cis rs7520050 0.807 rs4660312 chr1:46110572 A/G cg03146154 chr1:46216737 IPP 0.5 8.55 0.42 4.08e-16 Red blood cell count;Reticulocyte count; LIHC cis rs7572733 0.534 rs700673 chr2:198692929 A/G cg10820045 chr2:198174542 NA 0.46 6.9 0.35 2.59e-11 Dermatomyositis; LIHC cis rs1005277 0.579 rs2749612 chr10:38488610 G/A cg25427524 chr10:38739819 LOC399744 -0.72 -14.26 -0.61 1.58e-36 Extrinsic epigenetic age acceleration; LIHC cis rs12497850 0.931 rs9311433 chr3:48863835 T/C cg07636037 chr3:49044803 WDR6 0.93 16.94 0.68 3.74e-47 Parkinson's disease; LIHC cis rs637571 0.584 rs7107912 chr11:65603252 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.5 -7.45 -0.37 7.85e-13 Eosinophil percentage of white cells; LIHC cis rs7095944 0.554 rs11245344 chr10:126418782 C/T cg20435097 chr10:126320824 FAM53B 0.36 6.2 0.32 1.6e-9 Asthma; LIHC trans rs7613875 0.620 rs17657688 chr3:50033228 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.43 -6.58 -0.34 1.75e-10 Body mass index; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg13053135 chr2:234359932 DGKD -0.41 -6.25 -0.32 1.2e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs11792861 0.781 rs11789252 chr9:111762010 A/T cg13535736 chr9:111863775 C9orf5 -0.41 -6.07 -0.31 3.35e-9 Menarche (age at onset); LIHC cis rs11673344 0.764 rs519551 chr19:37455948 C/G cg27390819 chr19:37464633 NA -0.53 -6.29 -0.32 9.74e-10 Obesity-related traits; LIHC cis rs17685 0.712 rs6976236 chr7:75741087 G/T cg04610667 chr7:75704037 NA -0.33 -6.0 -0.31 5.08e-9 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs1005277 0.557 rs2983338 chr10:38550734 C/T cg23533926 chr12:111358616 MYL2 -0.36 -6.85 -0.35 3.46e-11 Extrinsic epigenetic age acceleration; LIHC cis rs17270561 0.779 rs17271767 chr6:25886921 C/T cg17691542 chr6:26056736 HIST1H1C 0.82 9.7 0.46 8.31e-20 Iron status biomarkers; LIHC cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg07677032 chr17:61819896 STRADA 0.44 6.3 0.32 9.29e-10 Prudent dietary pattern; LIHC cis rs11030122 0.702 rs10835407 chr11:3993231 C/T cg18678763 chr11:4115507 RRM1 0.57 8.47 0.42 7.24e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs67311347 1.000 rs951560 chr3:40463471 A/G cg00656387 chr3:40428638 ENTPD3 0.41 6.92 0.35 2.19e-11 Renal cell carcinoma; LIHC cis rs1570989 0.543 rs6458035 chr6:12015296 A/G cg17804551 chr6:12015979 HIVEP1 0.4 6.97 0.35 1.63e-11 Alcohol and nicotine co-dependence; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg24523535 chr1:9970042 CTNNBIP1 0.35 6.04 0.31 3.92e-9 Lobe attachment (rater-scored or self-reported); LIHC trans rs2797160 0.935 rs1739372 chr6:126011325 G/A cg05039488 chr6:79577232 IRAK1BP1 0.46 6.42 0.33 4.46e-10 Endometrial cancer; LIHC cis rs801193 1.000 rs2707854 chr7:66212597 G/A cg14393609 chr7:65229607 NA 0.37 5.73 0.3 2.25e-8 Aortic root size; LIHC cis rs7503807 1.000 rs12939613 chr17:78588202 A/G cg09596252 chr17:78655493 RPTOR 0.38 6.75 0.34 6.33e-11 Obesity; LIHC cis rs2228479 0.850 rs17226498 chr16:89840631 T/C cg06558623 chr16:89946397 TCF25 0.84 11.74 0.54 5.79e-27 Skin colour saturation; LIHC cis rs7131987 0.903 rs6487796 chr12:29422764 A/G cg21486233 chr12:29375141 FAR2 0.29 5.72 0.3 2.27e-8 QT interval; LIHC cis rs4742903 0.904 rs7028408 chr9:106859811 G/A cg14250997 chr9:106856677 SMC2 0.43 7.53 0.38 4.49e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs1003719 0.788 rs2835577 chr21:38457457 T/C cg10648535 chr21:38446584 PIGP;TTC3 0.78 12.21 0.55 1.02e-28 Eye color traits; LIHC cis rs3741798 1.000 rs61922045 chr12:12494394 A/C cg08615371 chr12:12503544 MANSC1 0.89 7.25 0.37 2.72e-12 Cerebrospinal fluid biomarker levels; LIHC cis rs875971 0.545 rs6961853 chr7:66002022 G/A cg11764359 chr7:65958608 NA 0.61 8.83 0.43 5.48e-17 Aortic root size; LIHC cis rs12477438 0.520 rs13009147 chr2:99803998 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.22 21.98 0.77 2.28e-67 Chronic sinus infection; LIHC cis rs4423214 1.000 rs12419279 chr11:71139061 T/A cg24826892 chr11:71159390 DHCR7 0.51 6.69 0.34 9.12e-11 Vitamin D levels; LIHC cis rs17253792 0.822 rs79483507 chr14:56164718 G/T cg01858014 chr14:56050164 KTN1 -0.71 -7.3 -0.37 1.98e-12 Putamen volume; LIHC cis rs7772486 0.790 rs2250387 chr6:146205233 C/T cg05347473 chr6:146136440 FBXO30 0.39 6.46 0.33 3.57e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.72 12.47 0.56 1.11e-29 Colorectal cancer; LIHC cis rs17286411 0.750 rs4788579 chr16:71951845 A/C cg06353428 chr16:71660113 MARVELD3 0.55 6.8 0.35 4.71e-11 Blood protein levels; LIHC cis rs892961 1.000 rs11077909 chr17:75403480 T/C cg01320579 chr17:75405842 SEPT9 0.5 8.97 0.44 2.02e-17 Airflow obstruction; LIHC cis rs67460515 0.563 rs16831886 chr3:160799830 A/C cg03342759 chr3:160939853 NMD3 -0.59 -8.36 -0.41 1.65e-15 Parkinson's disease; LIHC cis rs10504229 0.679 rs72649119 chr8:58040301 T/C cg02290350 chr8:58132656 NA 0.32 7.07 0.36 8.87e-12 Developmental language disorder (linguistic errors); LIHC cis rs7100689 0.646 rs7081889 chr10:82165427 C/A cg00277334 chr10:82204260 NA -0.47 -6.94 -0.35 1.97e-11 Post bronchodilator FEV1; LIHC cis rs7528419 1.000 rs12740374 chr1:109817590 G/T cg00908766 chr1:109817496 CELSR2 -0.48 -8.72 -0.43 1.27e-16 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; LIHC cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg12311346 chr5:56204834 C5orf35 -0.58 -7.62 -0.38 2.48e-13 Initial pursuit acceleration; LIHC cis rs1728785 1.000 rs1728780 chr16:68567642 G/C cg02972257 chr16:68554789 NA -0.52 -6.11 -0.31 2.79e-9 Ulcerative colitis; LIHC cis rs2380220 0.541 rs72928273 chr6:96079360 C/T cg23517279 chr6:96025343 MANEA -0.6 -6.13 -0.31 2.39e-9 Behavioural disinhibition (generation interaction); LIHC cis rs9381040 0.655 rs6903444 chr6:41014220 C/T cg25110423 chr6:41068646 NFYA;LOC221442 0.38 6.18 0.32 1.84e-9 Alzheimer's disease (late onset); LIHC cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg11905131 chr22:24372483 LOC391322 -0.69 -10.23 -0.48 1.34e-21 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs1385374 0.642 rs10847691 chr12:129287449 G/A cg21616243 chr12:129299702 MGC16384;SLC15A4 0.6 7.17 0.36 4.57e-12 Systemic lupus erythematosus; LIHC cis rs858239 0.601 rs987257 chr7:23147840 G/A cg23682824 chr7:23144976 KLHL7 0.45 6.78 0.34 5.43e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs6500602 0.702 rs2270366 chr16:4558615 A/G cg08345575 chr16:4524283 NMRAL1;HMOX2 -0.44 -6.32 -0.32 8.26e-10 Schizophrenia; LIHC cis rs6964587 1.000 rs13231820 chr7:91663529 A/G cg17063962 chr7:91808500 NA 1.01 19.48 0.73 2.12e-57 Breast cancer; LIHC cis rs1008375 1.000 rs13148861 chr4:17688338 G/A cg16339924 chr4:17578868 LAP3 -0.48 -6.01 -0.31 4.84e-9 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg07424592 chr7:64974309 NA 0.82 9.61 0.46 1.64e-19 Diabetic kidney disease; LIHC cis rs892961 0.836 rs35077273 chr17:75412415 T/C cg05865280 chr17:75406074 SEPT9 0.65 13.38 0.59 3.82e-33 Airflow obstruction; LIHC cis rs7432375 0.901 rs11919030 chr3:136348599 G/A cg21827317 chr3:136751795 NA 0.46 6.28 0.32 1.05e-9 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; LIHC cis rs7107174 1.000 rs10899481 chr11:78058721 A/T cg02023728 chr11:77925099 USP35 -0.41 -7.83 -0.39 5.98e-14 Testicular germ cell tumor; LIHC cis rs3008870 1.000 rs3008854 chr1:67385951 T/C cg02640540 chr1:67518911 SLC35D1 0.42 5.78 0.3 1.64e-8 Lymphocyte percentage of white cells; LIHC cis rs10540 1.000 rs12419766 chr11:503710 C/T cg03576123 chr11:487126 PTDSS2 -1.09 -8.24 -0.41 3.78e-15 Body mass index; LIHC cis rs9902453 0.900 rs56195309 chr17:28453753 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.87 0.43 4.04e-17 Coffee consumption (cups per day); LIHC cis rs7512552 0.839 rs11587575 chr1:150451863 T/C cg15654264 chr1:150340011 RPRD2 0.69 11.3 0.52 2.23e-25 Atopic dermatitis;Allergic disease (asthma, hay fever or eczema); LIHC cis rs1419980 1.000 rs1419980 chr12:7774892 A/G cg25828445 chr12:7781288 NA -0.49 -7.04 -0.36 1.06e-11 HDL cholesterol levels; LIHC cis rs9549367 0.713 rs4907593 chr13:113830459 C/T cg18105134 chr13:113819100 PROZ 0.61 10.83 0.51 1.06e-23 Platelet distribution width; LIHC cis rs908922 0.676 rs1970283 chr1:152495619 G/C cg20991723 chr1:152506922 NA 0.51 8.52 0.42 5.08e-16 Hair morphology; LIHC cis rs400736 0.930 rs408320 chr1:8085328 T/C cg25007680 chr1:8021821 PARK7 0.6 9.62 0.46 1.54e-19 Response to antidepressants and depression; LIHC cis rs4808199 0.948 rs12982276 chr19:19459800 T/C cg21559469 chr19:19431446 KIAA0892;SF4 0.43 5.87 0.3 1.02e-8 Nonalcoholic fatty liver disease; LIHC trans rs668210 0.739 rs1151511 chr11:65756283 A/G cg17712092 chr4:129076599 LARP1B 0.57 6.17 0.32 1.9e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs11822910 1.000 rs4529894 chr11:57199645 C/G cg00522883 chr11:57194120 SLC43A3 0.7 8.38 0.41 1.37e-15 Platelet distribution width; LIHC cis rs2274273 0.564 rs3783649 chr14:55834410 G/A cg01864836 chr14:55583639 NA -0.35 -5.82 -0.3 1.33e-8 Protein biomarker; LIHC cis rs858239 0.600 rs10237755 chr7:23131564 A/G cg23682824 chr7:23144976 KLHL7 0.45 6.78 0.34 5.17e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg13409248 chr3:40428643 ENTPD3 0.43 7.08 0.36 8.01e-12 Renal cell carcinoma; LIHC cis rs7103648 0.669 rs7927445 chr11:47780754 G/T cg20307385 chr11:47447363 PSMC3 0.98 15.78 0.65 1.63e-42 Diastolic blood pressure;Systolic blood pressure; LIHC cis rs2236918 0.901 rs1776132 chr1:242024473 C/G cg17736920 chr1:242011382 EXO1 0.57 8.44 0.42 9.28e-16 Menopause (age at onset); LIHC cis rs758324 0.947 rs2404778 chr5:131172886 T/C cg06307176 chr5:131281290 NA 0.41 5.96 0.31 6.36e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs2279817 1.000 rs10888048 chr1:18019742 C/T cg21791023 chr1:18019539 ARHGEF10L 0.64 8.73 0.43 1.12e-16 Neuroticism; LIHC cis rs4908768 0.911 rs953535 chr1:8776719 A/C cg25722041 chr1:8623473 RERE 0.42 5.91 0.3 8.51e-9 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs11122272 0.735 rs2790876 chr1:231536033 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.48 -0.49 1.84e-22 Hemoglobin concentration; LIHC cis rs62458065 0.513 rs10245103 chr7:32534829 T/G cg20159608 chr7:32802032 NA -0.48 -5.98 -0.31 5.49e-9 Metabolite levels (HVA/MHPG ratio); LIHC cis rs5769707 0.521 rs5770633 chr22:50062427 G/A cg07959070 chr22:50026188 C22orf34 -0.3 -7.19 -0.36 4.03e-12 Monocyte count;Monocyte percentage of white cells; LIHC cis rs875971 0.540 rs35510581 chr7:65578777 G/A cg14393609 chr7:65229607 NA -0.39 -5.85 -0.3 1.16e-8 Aortic root size; LIHC cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg11301795 chr4:187892539 NA -0.29 -7.8 -0.39 7.47e-14 Lobe attachment (rater-scored or self-reported); LIHC cis rs17433710 0.516 rs12036048 chr1:162658640 C/T cg01063088 chr1:162760584 HSD17B7 0.44 6.07 0.31 3.34e-9 Dupuytren's disease; LIHC trans rs59191668 0.903 rs2899680 chr15:62833859 A/G cg14990712 chr19:4055085 ZBTB7A 0.4 6.05 0.31 3.81e-9 Immature fraction of reticulocytes; LIHC cis rs10508774 1.000 rs72795571 chr10:32909933 A/G cg01819863 chr10:32635814 EPC1 0.64 5.84 0.3 1.21e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs9733 0.715 rs12402006 chr1:150869829 G/A cg18016565 chr1:150552671 MCL1 -0.49 -9.26 -0.45 2.28e-18 Tonsillectomy; LIHC cis rs4474465 0.915 rs12272791 chr11:78159426 G/A cg02023728 chr11:77925099 USP35 0.36 6.31 0.32 8.49e-10 Alzheimer's disease (survival time); LIHC cis rs694739 0.657 rs11231770 chr11:64140625 G/A cg02228329 chr11:64053129 BAD;GPR137 0.59 8.09 0.4 1.08e-14 Alopecia areata;Crohn's disease;Psoriasis vulgaris; LIHC cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg16049864 chr8:95962084 TP53INP1 -0.61 -11.31 -0.52 2.01e-25 Type 2 diabetes; LIHC cis rs35110281 0.837 rs2838336 chr21:45071741 A/G cg04455712 chr21:45112962 RRP1B -0.44 -7.91 -0.39 3.71e-14 Mean corpuscular volume; LIHC cis rs11628318 0.660 rs4906242 chr14:103085063 G/A cg12046867 chr14:103022105 NA -0.47 -6.79 -0.34 4.94e-11 Platelet count; LIHC trans rs3780486 0.718 rs3818593 chr9:33120706 A/G cg20290983 chr6:43655470 MRPS18A 0.96 15.06 0.63 1.1e-39 IgG glycosylation; LIHC cis rs17685 0.712 rs6976236 chr7:75741087 G/T cg04592579 chr7:75616294 TMEM120A 0.39 6.74 0.34 6.89e-11 Coffee consumption;Coffee consumption (cups per day); LIHC trans rs11760633 0.607 rs7789703 chr7:1829899 T/C cg00395210 chr12:48592465 NA 0.34 6.06 0.31 3.53e-9 Coronary artery disease; LIHC trans rs12960119 0.536 rs34515305 chr18:23732926 G/A cg05333146 chr16:67183725 B3GNT9 0.64 6.09 0.31 3e-9 Rhegmatogenous retinal detachment; LIHC cis rs2479724 0.846 rs2251084 chr6:41838119 T/C cg17623882 chr6:41773611 USP49 -0.55 -8.8 -0.43 6.67e-17 Menarche (age at onset); LIHC cis rs9682041 1.000 rs6773095 chr3:170082181 A/G cg11886554 chr3:170076028 SKIL 0.74 6.05 0.31 3.74e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); LIHC cis rs7944735 0.508 rs74335517 chr11:47479168 G/A cg20307385 chr11:47447363 PSMC3 -0.56 -6.34 -0.32 7.33e-10 Intraocular pressure; LIHC cis rs4665809 1.000 rs750451 chr2:26324241 G/A cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.53e-15 Gut microbiome composition (summer); LIHC cis rs9914988 0.943 rs4795465 chr17:27151498 A/G cg20469991 chr17:27169893 C17orf63 0.6 7.08 0.36 8.04e-12 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs11690935 0.571 rs13020884 chr2:172901699 T/G cg13550731 chr2:172543902 DYNC1I2 0.47 6.77 0.34 5.57e-11 Schizophrenia; LIHC cis rs6952808 0.531 rs3779003 chr7:2184902 C/T cg02951883 chr7:2050386 MAD1L1 -0.6 -9.52 -0.46 3.32e-19 Bipolar disorder and schizophrenia; LIHC cis rs12200782 1.000 rs72844496 chr6:26611608 G/A cg11502198 chr6:26597334 ABT1 -0.79 -5.73 -0.3 2.24e-8 Small cell lung carcinoma; LIHC cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.73 -5.85 -0.3 1.15e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs67311347 0.869 rs7646899 chr3:40366982 A/G cg24209194 chr3:40518798 ZNF619 0.45 6.34 0.32 7.37e-10 Renal cell carcinoma; LIHC cis rs651907 0.535 rs13065944 chr3:101473088 G/A cg03334568 chr3:101395165 ZBTB11;LOC100009676 -0.46 -6.45 -0.33 3.81e-10 Colorectal cancer; LIHC cis rs2795502 0.882 rs2744095 chr10:43337949 A/T cg27426351 chr10:43362370 NA -0.46 -5.75 -0.3 1.93e-8 Blood protein levels; LIHC cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 14.63 0.62 5.53e-38 Prudent dietary pattern; LIHC cis rs4243830 0.850 rs4908904 chr1:6580250 A/G cg22792644 chr1:6614718 TAS1R1;NOL9 0.7 9.82 0.47 3.22e-20 Body mass index; LIHC cis rs11212260 0.655 rs17106918 chr11:107287701 C/T cg25435332 chr11:107328525 CWF19L2 0.8 8.13 0.4 7.75e-15 IgG glycosylation; LIHC trans rs61931739 0.500 rs10844863 chr12:34532284 C/T cg26384229 chr12:38710491 ALG10B 0.62 7.93 0.39 3.23e-14 Morning vs. evening chronotype; LIHC cis rs778371 0.578 rs2675956 chr2:233753340 G/A cg25237894 chr2:233734115 C2orf82 -0.4 -7.45 -0.37 7.93e-13 Schizophrenia; LIHC cis rs7216064 0.953 rs12450907 chr17:65870644 T/G cg12091567 chr17:66097778 LOC651250 -0.66 -9.31 -0.45 1.61e-18 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs35110281 0.626 rs162368 chr21:44934767 G/A cg21573476 chr21:45109991 RRP1B -0.41 -7.57 -0.38 3.48e-13 Mean corpuscular volume; LIHC cis rs2070488 0.965 rs7372849 chr3:38524328 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 16.17 0.66 4.4e-44 Electrocardiographic conduction measures; LIHC cis rs12477438 0.501 rs11683188 chr2:99724512 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.62 9.86 0.47 2.31e-20 Chronic sinus infection; LIHC cis rs3820500 0.543 rs1289938 chr1:117944341 G/A cg20383390 chr1:117909022 MAN1A2 0.47 6.04 0.31 4.03e-9 Pneumonia; LIHC cis rs2952156 0.684 rs11658786 chr17:37815899 G/A cg07936489 chr17:37558343 FBXL20 -0.45 -6.76 -0.34 6e-11 Asthma; LIHC cis rs1568889 1.000 rs12287732 chr11:28120845 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.47 6.67 0.34 1e-10 Bipolar disorder; LIHC cis rs6500602 0.647 rs1659497 chr16:4594635 G/A cg08645402 chr16:4508243 NA -0.37 -6.86 -0.35 3.27e-11 Schizophrenia; LIHC cis rs17685 0.725 rs1044483 chr7:75659815 T/C cg04592579 chr7:75616294 TMEM120A -0.39 -6.77 -0.34 5.63e-11 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs11888559 0.573 rs10190966 chr2:203792816 A/G cg24605529 chr2:203879461 NBEAL1 -0.66 -5.73 -0.3 2.19e-8 Height; LIHC cis rs1005277 0.540 rs289638 chr10:37923731 G/A cg00409905 chr10:38381863 ZNF37A -0.57 -9.83 -0.47 3.09e-20 Extrinsic epigenetic age acceleration; LIHC cis rs34779708 0.966 rs17591163 chr10:35465279 G/C cg03585969 chr10:35415529 CREM 0.87 13.14 0.58 3.4e-32 Inflammatory bowel disease;Crohn's disease; LIHC cis rs17102884 0.506 rs887746 chr14:75403817 C/T cg08847533 chr14:75593920 NEK9 -0.61 -10.81 -0.5 1.29e-23 Neuroticism; LIHC cis rs3008870 1.000 rs2815370 chr1:67503727 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.98 -16.34 -0.66 8.97e-45 Lymphocyte percentage of white cells; LIHC cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg02034447 chr16:89574710 SPG7 0.44 6.76 0.34 5.96e-11 Multiple myeloma (IgH translocation); LIHC trans rs8073060 0.544 rs225258 chr17:33956883 C/T cg19694781 chr19:47549865 TMEM160 -1.26 -14.13 -0.61 4.86e-36 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs4319547 1.000 rs10998 chr12:122989412 G/A cg23029597 chr12:123009494 RSRC2 -0.54 -7.64 -0.38 2.26e-13 Body mass index; LIHC trans rs7819412 0.635 rs2409716 chr8:11010748 C/T cg25387593 chr11:118927868 HYOU1 -0.46 -6.52 -0.33 2.52e-10 Triglycerides; LIHC cis rs2153535 0.580 rs1335637 chr6:8465101 A/G cg23788917 chr6:8435910 SLC35B3 0.61 8.6 0.42 2.82e-16 Motion sickness; LIHC cis rs6089584 0.888 rs6061982 chr20:60620673 C/T cg23262073 chr20:60523788 NA -0.29 -6.16 -0.32 2.09e-9 Body mass index; LIHC cis rs1005277 0.505 rs200936 chr10:38134935 T/C cg00409905 chr10:38381863 ZNF37A -0.55 -9.5 -0.46 3.75e-19 Extrinsic epigenetic age acceleration; LIHC cis rs262150 0.574 rs2730272 chr7:158798622 G/C cg19418458 chr7:158789849 NA -0.4 -6.67 -0.34 1.05e-10 Facial morphology (factor 20); LIHC cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg11644478 chr21:40555479 PSMG1 0.83 10.86 0.51 8.58e-24 Cognitive function; LIHC cis rs9291683 0.567 rs12499857 chr4:9995376 G/A cg11266682 chr4:10021025 SLC2A9 0.31 6.45 0.33 3.71e-10 Bone mineral density; LIHC cis rs898097 0.737 rs3785521 chr17:80895769 A/G cg15664640 chr17:80829946 TBCD 0.67 10.5 0.49 1.59e-22 Breast cancer; LIHC cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg10802521 chr3:52805072 NEK4 -0.45 -7.54 -0.38 4.15e-13 Intelligence (multi-trait analysis); LIHC cis rs597539 0.652 rs622082 chr11:68703959 A/G cg04772025 chr11:68637568 NA 0.49 6.31 0.32 8.85e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs4319547 1.000 rs6489157 chr12:123101673 C/G cg05707623 chr12:122985044 ZCCHC8 0.57 7.63 0.38 2.39e-13 Body mass index; LIHC cis rs7412746 0.611 rs10788794 chr1:150728676 T/C cg18016565 chr1:150552671 MCL1 0.56 10.79 0.5 1.48e-23 Melanoma; LIHC cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg12379764 chr21:47803548 PCNT -0.54 -7.99 -0.4 2.08e-14 Testicular germ cell tumor; LIHC cis rs2204008 0.837 rs11168504 chr12:37964922 G/T cg26384229 chr12:38710491 ALG10B 0.86 10.7 0.5 2.95e-23 Bladder cancer; LIHC cis rs7613875 0.600 rs2247510 chr3:50126215 A/C cg24110177 chr3:50126178 RBM5 -0.57 -9.26 -0.45 2.25e-18 Body mass index; LIHC cis rs701145 0.556 rs355771 chr3:154039385 G/C cg16511985 chr3:153974050 SGEF 0.42 8.93 0.43 2.62e-17 Coronary artery disease; LIHC cis rs929354 0.709 rs1182363 chr7:157019151 A/G cg17757837 chr7:157058334 UBE3C -0.74 -12.05 -0.55 4.28e-28 Body mass index; LIHC cis rs10752881 1.000 rs6424879 chr1:182986592 T/C ch.1.3577855R chr1:183094577 LAMC1 0.59 10.32 0.49 6.52e-22 Colorectal cancer; LIHC cis rs9768139 0.708 rs10233815 chr7:158114348 C/T cg25566285 chr7:158114605 PTPRN2 0.22 6.02 0.31 4.4e-9 Calcium levels; LIHC cis rs4906332 0.933 rs35999760 chr14:103924481 A/C cg19000871 chr14:103996768 TRMT61A -0.47 -7.94 -0.39 2.98e-14 Coronary artery disease; LIHC cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.01 -9.98 -0.48 9.07e-21 Platelet count; LIHC cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg13271783 chr10:134563150 INPP5A -0.6 -7.17 -0.36 4.71e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs58235267 0.656 rs13410889 chr2:63087778 T/C cg17519650 chr2:63277830 OTX1 0.53 8.68 0.43 1.59e-16 Prostate-specific antigen levels (conditioned on lead SNPs); LIHC cis rs748404 0.697 rs473554 chr15:43568207 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.44 6.67 0.34 1.03e-10 Lung cancer; LIHC cis rs8084351 0.577 rs12607872 chr18:50658496 G/A cg24270629 chr18:50823537 DCC -0.44 -6.42 -0.33 4.55e-10 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); LIHC cis rs9733 0.596 rs11204687 chr1:150629880 C/A cg17724175 chr1:150552817 MCL1 0.48 9.73 0.47 6.42e-20 Tonsillectomy; LIHC cis rs7503807 0.905 rs9909449 chr17:78614393 A/G cg09596252 chr17:78655493 RPTOR 0.4 7.07 0.36 9.04e-12 Obesity; LIHC cis rs765787 0.505 rs1648302 chr15:45494238 A/G cg24006582 chr15:45444508 DUOX1 -0.53 -7.53 -0.38 4.53e-13 Uric acid levels; LIHC cis rs2033711 0.840 rs10423138 chr19:58928302 T/C cg00825309 chr19:58991885 ZNF446 -0.62 -9.55 -0.46 2.5e-19 Uric acid clearance; LIHC cis rs2153535 0.580 rs7761937 chr6:8459434 A/T cg07606381 chr6:8435919 SLC35B3 0.81 11.9 0.54 1.43e-27 Motion sickness; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg11229284 chr3:122399506 PARP14 0.53 6.78 0.34 5.41e-11 Lung function (FEV1/FVC); LIHC cis rs4319547 0.737 rs10846921 chr12:122943376 G/T cg05707623 chr12:122985044 ZCCHC8 0.53 7.27 0.37 2.41e-12 Body mass index; LIHC cis rs7044106 0.708 rs1324472 chr9:123375110 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.5 7.56 0.38 3.76e-13 Hip circumference adjusted for BMI; LIHC cis rs780096 0.526 rs72819536 chr2:27682850 G/T cg27432699 chr2:27873401 GPN1 -0.54 -7.82 -0.39 6.44e-14 Total body bone mineral density; LIHC cis rs875971 1.000 rs3735148 chr7:65971009 T/G cg18876405 chr7:65276391 NA 0.37 6.75 0.34 6.31e-11 Aortic root size; LIHC cis rs28735056 0.563 rs55642704 chr18:77688124 C/T cg20368463 chr18:77673604 PQLC1 -0.56 -10.4 -0.49 3.35e-22 Schizophrenia; LIHC cis rs2281558 0.754 rs73597824 chr20:25591477 C/T cg13962466 chr20:25176127 ENTPD6 -0.41 -5.79 -0.3 1.56e-8 Peripheral arterial disease (traffic-related air pollution interaction);Calcium levels; LIHC cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg08677398 chr8:58056175 NA 0.41 6.28 0.32 1.03e-9 Developmental language disorder (linguistic errors); LIHC cis rs1538970 0.961 rs4660854 chr1:45854087 A/T cg05343316 chr1:45956843 TESK2 0.52 7.84 0.39 5.62e-14 Platelet count; LIHC cis rs1538970 0.816 rs4633317 chr1:45985157 T/C cg05343316 chr1:45956843 TESK2 0.61 8.48 0.42 6.98e-16 Platelet count; LIHC cis rs780096 0.527 rs59644396 chr2:27646083 A/G cg22903471 chr2:27725779 GCKR -0.47 -8.09 -0.4 1.02e-14 Total body bone mineral density; LIHC cis rs7264396 0.511 rs2425102 chr20:34312303 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.79 -0.43 7.44e-17 Total cholesterol levels; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg11114853 chr2:242626719 DTYMK 0.44 6.14 0.32 2.27e-9 Alopecia areata; LIHC cis rs7927592 0.913 rs11228287 chr11:68349754 A/G cg16797656 chr11:68205561 LRP5 0.5 7.8 0.39 7.44e-14 Total body bone mineral density; LIHC cis rs2279817 0.863 rs871087 chr1:18017522 T/C cg21791023 chr1:18019539 ARHGEF10L 0.68 8.05 0.4 1.36e-14 Neuroticism; LIHC cis rs780096 0.565 rs8179252 chr2:27746832 A/C cg22903471 chr2:27725779 GCKR -0.47 -8.08 -0.4 1.13e-14 Total body bone mineral density; LIHC cis rs1892700 0.840 rs62226457 chr21:34870990 G/A cg14850771 chr21:34775459 IFNGR2 -0.43 -5.75 -0.3 1.97e-8 Educational attainment; LIHC cis rs116095464 0.558 rs73024831 chr5:257192 A/G cg22496380 chr5:211416 CCDC127 -1.03 -10.69 -0.5 3.34e-23 Breast cancer; LIHC cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.8 15.0 0.63 1.98e-39 Prudent dietary pattern; LIHC cis rs1434579 0.897 rs8102733 chr19:44944448 A/G cg15540054 chr19:45004280 ZNF180 0.54 7.59 0.38 3.16e-13 Tuberculosis; LIHC cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg00800038 chr16:89945340 TCF25 -0.66 -10.55 -0.5 1.04e-22 Skin colour saturation; LIHC cis rs9918079 0.560 rs7662032 chr4:15635414 C/G cg04067612 chr4:15429572 C1QTNF7 -0.28 -5.88 -0.3 9.93e-9 Obesity-related traits; LIHC cis rs61990749 0.597 rs2299930 chr14:78163722 C/T cg21497246 chr14:78225524 SNW1;C14orf178 0.48 7.22 0.36 3.49e-12 Fibroblast growth factor basic levels; LIHC cis rs611744 0.870 rs416611 chr8:109124593 T/C cg21045802 chr8:109455806 TTC35 0.5 8.48 0.42 6.86e-16 Dupuytren's disease; LIHC cis rs2304069 0.545 rs6866616 chr5:149415401 A/G cg22760475 chr5:149380129 HMGXB3;TIGD6 0.61 8.63 0.42 2.37e-16 HIV-1 control; LIHC cis rs12220238 1.000 rs10824128 chr10:76007903 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.64 6.64 0.34 1.25e-10 Soluble interleukin-2 receptor subunit alpha; LIHC cis rs6695567 0.967 rs6588468 chr1:53630648 A/G cg20326410 chr1:53600821 SLC1A7 0.3 6.34 0.32 7.22e-10 Systemic lupus erythematosus; LIHC cis rs2549003 0.966 rs2706385 chr5:131831766 T/G cg21138405 chr5:131827807 IRF1 -0.38 -9.96 -0.47 1.07e-20 Asthma (sex interaction); LIHC trans rs4650994 1.000 rs4650993 chr1:178515187 A/G cg05059571 chr16:84539110 KIAA1609 -0.38 -6.35 -0.32 6.9e-10 HDL cholesterol levels;HDL cholesterol; LIHC cis rs477692 0.569 rs7087541 chr10:131309979 A/C cg19680672 chr10:131412579 MGMT -0.38 -5.74 -0.3 2.1e-8 Response to temozolomide; LIHC cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg18404041 chr3:52824283 ITIH1 -0.57 -9.17 -0.44 4.56e-18 Bipolar disorder; LIHC cis rs4631830 0.737 rs7071471 chr10:51503335 C/T cg20129853 chr10:51489980 NA 0.42 9.03 0.44 1.32e-17 Prostate-specific antigen levels; LIHC cis rs3768617 0.510 rs7525917 chr1:183065406 A/G ch.1.3577855R chr1:183094577 LAMC1 0.62 10.8 0.5 1.42e-23 Fuchs's corneal dystrophy; LIHC cis rs2637266 0.935 rs2583057 chr10:78396019 C/T cg18941641 chr10:78392320 NA 0.29 6.4 0.33 5.23e-10 Pulmonary function; LIHC cis rs7613875 0.654 rs3774751 chr3:50209053 G/T cg12708802 chr3:50388878 TUSC4;CYB561D2 -0.45 -6.54 -0.33 2.28e-10 Body mass index; LIHC cis rs2842992 0.724 rs2273827 chr6:160211339 C/A cg11366901 chr6:160182831 ACAT2 0.86 14.38 0.61 5.22e-37 Age-related macular degeneration (geographic atrophy); LIHC cis rs3750965 0.919 rs12280942 chr11:68859683 A/G cg06846819 chr11:68850022 TPCN2 0.4 6.28 0.32 1.04e-9 Hair color; LIHC cis rs2153535 0.562 rs10458225 chr6:8386004 G/A cg21535247 chr6:8435926 SLC35B3 -0.6 -8.33 -0.41 2.03e-15 Motion sickness; LIHC cis rs5769765 1.000 rs2295409 chr22:50261060 G/C cg26441486 chr22:50317300 CRELD2 -0.34 -6.05 -0.31 3.79e-9 Schizophrenia; LIHC cis rs72627123 0.867 rs17093884 chr14:74482039 A/G cg11191049 chr14:74485465 ENTPD5;C14orf45 0.64 6.02 0.31 4.61e-9 Morning vs. evening chronotype; LIHC cis rs651907 0.535 rs17347156 chr3:101504674 G/A cg11279151 chr3:101281821 RG9MTD1 -0.39 -5.91 -0.3 8.08e-9 Colorectal cancer; LIHC cis rs1153858 0.887 rs28569043 chr15:45730926 A/T cg14582100 chr15:45693742 SPATA5L1 0.29 5.88 0.3 9.68e-9 Homoarginine levels; LIHC cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg06618935 chr21:46677482 NA -0.3 -5.74 -0.3 2.11e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg08677398 chr8:58056175 NA 0.41 6.29 0.32 9.72e-10 Developmental language disorder (linguistic errors); LIHC cis rs7208859 0.673 rs11653955 chr17:29033292 C/A cg13385521 chr17:29058706 SUZ12P 0.82 7.98 0.4 2.27e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs34779708 0.733 rs61449529 chr10:35543914 T/C cg03585969 chr10:35415529 CREM 0.76 11.02 0.51 2.18e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs116095464 0.558 rs28635197 chr5:279071 T/C cg22857025 chr5:266934 NA -1.48 -18.37 -0.7 6.13e-53 Breast cancer; LIHC cis rs919433 0.679 rs1598469 chr2:198515658 T/C cg10820045 chr2:198174542 NA 0.46 7.2 0.36 3.84e-12 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs9858542 0.953 rs1873625 chr3:49666964 C/A cg03060546 chr3:49711283 APEH -0.6 -7.97 -0.4 2.35e-14 Ulcerative colitis;Blood protein levels;Crohn's disease; LIHC cis rs273218 1.000 rs273218 chr5:53380555 T/C ch.5.1024479R chr5:53302184 ARL15 0.64 10.13 0.48 2.8e-21 Migraine; LIHC cis rs7212590 0.581 rs8069418 chr17:57818213 A/G cg10252138 chr17:58120427 NA -0.63 -6.08 -0.31 3.26e-9 Granulocyte percentage of myeloid white cells;Monocyte count;Monocyte percentage of white cells; LIHC cis rs1775715 0.651 rs2808033 chr10:32194127 A/T cg14930904 chr10:32216787 ARHGAP12 0.35 6.07 0.31 3.49e-9 Bipolar disorder with mood-incongruent psychosis; LIHC cis rs881375 0.678 rs10739581 chr9:123696871 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 6.31 0.32 8.85e-10 Rheumatoid arthritis; LIHC cis rs9837602 0.507 rs6803204 chr3:99680874 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.15 0.36 5.37e-12 Breast cancer; LIHC cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg21782813 chr7:2030301 MAD1L1 0.37 6.44 0.33 4.04e-10 Schizophrenia; LIHC cis rs10508774 1.000 rs12250212 chr10:32950637 C/T cg01819863 chr10:32635814 EPC1 0.63 5.88 0.3 9.88e-9 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs5769707 0.967 rs4524218 chr22:50018639 G/A cg07959070 chr22:50026188 C22orf34 -0.33 -8.68 -0.42 1.61e-16 Monocyte count;Monocyte percentage of white cells; LIHC cis rs523522 0.962 rs10849753 chr12:120910813 C/T cg27279351 chr12:120934652 DYNLL1 0.67 11.84 0.54 2.46e-27 High light scatter reticulocyte count; LIHC cis rs7106204 0.514 rs7117803 chr11:24253214 A/T ch.11.24196551F chr11:24239977 NA 0.82 11.75 0.54 5.24e-27 Response to Homoharringtonine (cytotoxicity); LIHC cis rs765787 0.530 rs28733848 chr15:45516047 C/T cg25801113 chr15:45476975 SHF 0.38 6.4 0.33 5.1e-10 Uric acid levels; LIHC cis rs11122272 0.735 rs2749714 chr1:231538634 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -10.47 -0.49 1.91e-22 Hemoglobin concentration; LIHC cis rs11105298 0.891 rs1008764 chr12:89887649 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -7.55 -0.38 3.92e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs1670533 1.000 rs11247972 chr4:1060550 A/G cg27284194 chr4:1044797 NA 0.59 8.71 0.43 1.37e-16 Recombination rate (females); LIHC cis rs2016586 0.773 rs5999962 chr22:36105655 T/C cg26342177 chr22:36113512 APOL5 -0.36 -6.23 -0.32 1.38e-9 Body mass index; LIHC cis rs9811920 0.581 rs793468 chr3:99538346 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 7.13 0.36 6.18e-12 Axial length; LIHC cis rs6545883 0.929 rs6545873 chr2:61733012 T/C cg14146966 chr2:61757674 XPO1 0.49 8.62 0.42 2.6e-16 Tuberculosis; LIHC cis rs7187994 0.848 rs35210690 chr16:84782857 C/G cg07647771 chr16:84786436 USP10 -0.33 -6.47 -0.33 3.47e-10 Reticulocyte count;Reticulocyte fraction of red cells; LIHC cis rs9325144 0.505 rs7955162 chr12:38711658 G/A cg26384229 chr12:38710491 ALG10B 0.59 9.45 0.46 5.47e-19 Morning vs. evening chronotype; LIHC cis rs4555082 0.874 rs1008628 chr14:105722726 T/C cg10792982 chr14:105748885 BRF1 0.45 6.18 0.32 1.85e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs765787 0.530 rs1631533 chr15:45518628 C/T cg24006582 chr15:45444508 DUOX1 -0.52 -7.49 -0.38 6.06e-13 Uric acid levels; LIHC cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg08067268 chr2:26466485 HADHB;HADHA -0.47 -6.73 -0.34 7.04e-11 Gut microbiome composition (summer); LIHC trans rs61931739 0.534 rs1352206 chr12:34036668 G/A cg26384229 chr12:38710491 ALG10B 0.45 6.41 0.33 4.71e-10 Morning vs. evening chronotype; LIHC cis rs3736485 0.966 rs11070854 chr15:51808365 A/G cg08986416 chr15:51914746 DMXL2 -0.4 -5.84 -0.3 1.25e-8 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs7208859 0.673 rs216418 chr17:28936537 G/A cg13385521 chr17:29058706 SUZ12P 0.57 5.78 0.3 1.67e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600806 0.676 rs573491 chr1:110026891 T/G cg23091122 chr1:110024289 SYPL2 0.45 6.07 0.31 3.37e-9 Intelligence (multi-trait analysis); LIHC cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.43 -6.54 -0.33 2.29e-10 Menarche (age at onset); LIHC trans rs17685 0.784 rs1637043 chr7:75699099 G/A cg19862616 chr7:65841803 NCRNA00174 0.93 19.29 0.72 1.27e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs7945705 0.935 rs2653567 chr11:8889630 T/C cg12365402 chr11:9010492 NRIP3 -0.24 -6.29 -0.32 9.51e-10 Hemoglobin concentration; LIHC cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg11645453 chr3:52864694 ITIH4 0.22 5.73 0.3 2.18e-8 Bipolar disorder; LIHC cis rs1577917 1.000 rs12196037 chr6:86694631 G/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A -0.41 -6.62 -0.34 1.37e-10 Response to antipsychotic treatment; LIHC cis rs17685 0.712 rs10271413 chr7:75754858 G/A cg16489192 chr7:75678113 MDH2;STYXL1 -0.39 -6.3 -0.32 9.34e-10 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs2404618 0.506 rs12156177 chr8:1493684 C/T cg13402656 chr8:1511478 DLGAP2 -0.46 -9.04 -0.44 1.2e-17 Lung cancer; LIHC cis rs6061231 0.837 rs6121558 chr20:60961365 A/G cg24112000 chr20:60950667 NA -0.58 -7.89 -0.39 4.05e-14 Colorectal cancer; LIHC cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg10755058 chr3:40428713 ENTPD3 0.41 7.03 0.36 1.15e-11 Renal cell carcinoma; LIHC cis rs735396 1.000 rs2259852 chr12:121434833 G/A cg02403541 chr12:121454288 C12orf43 0.46 8.12 0.4 8.52e-15 N-glycan levels; LIHC cis rs4638749 0.677 rs2378098 chr2:108849381 T/C cg25838818 chr2:108905173 SULT1C2 -0.39 -6.81 -0.35 4.27e-11 Blood pressure; LIHC cis rs13108904 0.557 rs1250097 chr4:1238338 C/T cg20887711 chr4:1340912 KIAA1530 -0.71 -10.72 -0.5 2.64e-23 Obesity-related traits; LIHC cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg08132940 chr7:1081526 C7orf50 -0.79 -6.67 -0.34 1.01e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs12477438 0.520 rs6712704 chr2:99719687 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.92 14.05 0.6 1.02e-35 Chronic sinus infection; LIHC trans rs2727020 0.595 rs10769583 chr11:49483193 G/A cg03929089 chr4:120376271 NA -0.89 -17.96 -0.7 2.75e-51 Coronary artery disease; LIHC cis rs68170813 0.641 rs4730228 chr7:106904077 T/C cg02696742 chr7:106810147 HBP1 -0.51 -5.96 -0.31 6.38e-9 Coronary artery disease; LIHC trans rs1005277 0.505 rs7917943 chr10:38195811 T/A cg17830980 chr10:43048298 ZNF37B 0.47 9.06 0.44 1.04e-17 Extrinsic epigenetic age acceleration; LIHC cis rs11030122 0.661 rs4910877 chr11:4062153 A/G cg18678763 chr11:4115507 RRM1 -0.56 -8.61 -0.42 2.74e-16 Mean platelet volume;Platelet distribution width; LIHC cis rs7264396 0.616 rs6142476 chr20:34581216 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.49 -8.64 -0.42 2.14e-16 Total cholesterol levels; LIHC trans rs9951602 0.512 rs12607612 chr18:76651799 G/A cg02800362 chr5:177631904 HNRNPAB 0.66 10.52 0.49 1.33e-22 Obesity-related traits; LIHC cis rs651907 0.535 rs1460097 chr3:101497569 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.67 11.23 0.52 3.88e-25 Colorectal cancer; LIHC cis rs6570726 0.846 rs6899900 chr6:145883873 T/G cg13319975 chr6:146136371 FBXO30 -0.35 -5.86 -0.3 1.12e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs9948 0.655 rs7568206 chr2:97393108 A/C cg01990225 chr2:97406019 LMAN2L -0.77 -6.44 -0.33 4.06e-10 Erectile dysfunction and prostate cancer treatment; LIHC cis rs644799 0.544 rs1254935 chr11:95631470 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.57 8.97 0.44 2e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs2455799 0.574 rs2102212 chr3:15704223 C/T cg12698662 chr3:15914712 MIR563 -0.39 -7.15 -0.36 5.15e-12 Mean platelet volume; LIHC trans rs637571 0.607 rs575479 chr11:65690300 T/G cg17712092 chr4:129076599 LARP1B 0.8 13.8 0.6 9.31e-35 Eosinophil percentage of white cells; LIHC cis rs7264396 0.673 rs2425163 chr20:34432670 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.64 -10.78 -0.5 1.65e-23 Total cholesterol levels; LIHC cis rs936229 0.656 rs2290572 chr15:75130573 A/G cg14664628 chr15:75095509 CSK -0.58 -9.06 -0.44 1e-17 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); LIHC cis rs1670533 0.929 rs6599280 chr4:1063818 A/G cg27284194 chr4:1044797 NA 0.59 8.73 0.43 1.11e-16 Recombination rate (females); LIHC cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.85 -11.08 -0.51 1.35e-24 Alzheimer's disease; LIHC cis rs798554 0.718 rs1636247 chr7:2881917 A/G cg13628971 chr7:2884303 GNA12 0.61 10.03 0.48 6.5e-21 Height; LIHC cis rs10492096 1.000 rs11064210 chr12:6576721 C/T cg13857086 chr12:6580257 VAMP1 0.57 5.93 0.31 7.31e-9 Hip geometry; LIHC cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg26338869 chr17:61819248 STRADA 0.53 7.18 0.36 4.33e-12 Height; LIHC cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg14004847 chr7:1930337 MAD1L1 -0.42 -5.94 -0.31 7.2e-9 Bipolar disorder and schizophrenia; LIHC cis rs67311347 0.713 rs114569261 chr3:40314580 G/A cg00656387 chr3:40428638 ENTPD3 0.4 6.34 0.32 7.18e-10 Renal cell carcinoma; LIHC cis rs9611565 0.512 rs132767 chr22:42009520 C/T cg03806693 chr22:41940476 POLR3H -0.83 -8.89 -0.43 3.6e-17 Vitiligo; LIHC cis rs2112347 0.502 rs34339 chr5:74931333 G/T cg08253296 chr5:74907592 NA -0.5 -6.18 -0.32 1.85e-9 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; LIHC cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg26939375 chr7:64535504 NA -0.46 -7.07 -0.36 8.99e-12 Aortic root size; LIHC cis rs9814567 0.752 rs6779326 chr3:134330027 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.58 -9.61 -0.46 1.7e-19 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs7246657 0.943 rs8109632 chr19:37931125 A/T cg10208301 chr11:6592745 DNHD1 0.46 6.64 0.34 1.23e-10 Coronary artery calcification; LIHC cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg24693881 chr1:107596107 NA 0.55 9.51 0.46 3.4e-19 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs17401966 0.867 rs12403443 chr1:10423988 A/G cg15208524 chr1:10270712 KIF1B 0.45 6.36 0.33 6.38e-10 Hepatocellular carcinoma; LIHC trans rs11098499 0.754 rs7672594 chr4:120248543 A/C cg25214090 chr10:38739885 LOC399744 0.51 8.31 0.41 2.32e-15 Corneal astigmatism; LIHC cis rs7551222 0.721 rs4951402 chr1:204539122 C/T cg20240347 chr1:204465584 NA -0.33 -6.93 -0.35 2.08e-11 Schizophrenia; LIHC cis rs9287719 0.625 rs7567304 chr2:10790029 T/C cg02829992 chr2:10710499 NA 0.38 5.95 0.31 6.56e-9 Prostate cancer; LIHC cis rs758324 0.853 rs6882899 chr5:131172467 G/C cg06307176 chr5:131281290 NA 0.4 5.75 0.3 1.93e-8 Alzheimer's disease in APOE e4- carriers; LIHC cis rs7903847 0.642 rs11189200 chr10:99156273 C/G cg08345082 chr10:99160200 RRP12 -0.39 -6.58 -0.34 1.81e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg05368731 chr17:41323189 NBR1 0.72 12.41 0.56 1.82e-29 Menopause (age at onset); LIHC cis rs1215050 0.740 rs700740 chr4:98976003 A/C cg05340658 chr4:99064831 C4orf37 -0.4 -6.16 -0.32 2.04e-9 Waist-to-hip ratio adjusted for body mass index; LIHC cis rs11955398 0.521 rs6449489 chr5:60026236 A/G cg02684056 chr5:59996105 DEPDC1B -0.4 -5.85 -0.3 1.12e-8 Intelligence (multi-trait analysis); LIHC cis rs875971 0.638 rs801216 chr7:66011667 T/C cg11764359 chr7:65958608 NA -0.72 -11.04 -0.51 1.9e-24 Aortic root size; LIHC cis rs7647973 0.826 rs9834535 chr3:49378797 A/T cg07636037 chr3:49044803 WDR6 0.51 6.24 0.32 1.28e-9 Menarche (age at onset); LIHC cis rs911119 0.908 rs6048949 chr20:23603199 C/T cg16589663 chr20:23618590 CST3 0.75 7.89 0.39 4.1e-14 Chronic kidney disease; LIHC cis rs8032158 1.000 rs11632096 chr15:56210499 A/G cg24530489 chr15:56299380 NA 0.42 5.91 0.3 8.28e-9 Keloid; LIHC cis rs55665837 1.000 rs11023246 chr11:14536956 T/C cg19336497 chr11:14380999 RRAS2 -0.45 -8.15 -0.4 7.1e-15 Vitamin D levels; LIHC cis rs754466 0.957 rs61854183 chr10:79698077 T/C cg17075019 chr10:79541650 NA -0.57 -7.45 -0.37 7.54e-13 Liver enzyme levels (gamma-glutamyl transferase); LIHC cis rs3096299 0.748 rs3102339 chr16:89442711 C/T cg08822215 chr16:89438651 ANKRD11 -0.48 -7.64 -0.38 2.28e-13 Multiple myeloma (IgH translocation); LIHC cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.54 0.8 2.06e-77 Prudent dietary pattern; LIHC cis rs6952808 0.771 rs10269191 chr7:1915731 A/G cg21782813 chr7:2030301 MAD1L1 0.42 7.02 0.35 1.23e-11 Bipolar disorder and schizophrenia; LIHC cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg10360323 chr17:41437877 NA 0.4 5.92 0.31 7.69e-9 Menopause (age at onset); LIHC cis rs2273156 0.706 rs35030792 chr14:35489123 C/T cg16230307 chr14:35515116 FAM177A1 -0.43 -6.19 -0.32 1.68e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg08233173 chr5:172410692 ATP6V0E1 -0.55 -6.91 -0.35 2.35e-11 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs311392 0.554 rs2013501 chr8:55104313 A/G cg20636351 chr8:55087400 NA -0.34 -7.0 -0.35 1.32e-11 Pelvic organ prolapse (moderate/severe); LIHC cis rs6504663 0.586 rs60117965 chr17:48569755 G/A cg00901687 chr17:48585270 MYCBPAP 0.47 6.32 0.32 8.15e-10 Visceral fat; LIHC cis rs826838 0.651 rs12367384 chr12:38618460 G/T cg26384229 chr12:38710491 ALG10B 0.45 7.06 0.36 9.05e-12 Heart rate; LIHC cis rs7617773 0.817 rs79310258 chr3:48259667 C/G cg11946769 chr3:48343235 NME6 0.89 10.97 0.51 3.51e-24 Coronary artery disease; LIHC cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs908922 0.676 rs12116609 chr1:152497685 C/T cg20991723 chr1:152506922 NA 0.6 10.59 0.5 7.3e-23 Hair morphology; LIHC cis rs6495122 0.532 rs2470890 chr15:75047426 C/T cg14664628 chr15:75095509 CSK -0.53 -7.24 -0.36 3.05e-12 Caffeine consumption;Diastolic blood pressure;Coffee consumption; LIHC cis rs6456156 0.586 rs1407315 chr6:167468659 A/G cg07741184 chr6:167504864 NA 0.29 6.86 0.35 3.3e-11 Primary biliary cholangitis; LIHC cis rs344364 0.511 rs62040571 chr16:1948514 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.56 -7.38 -0.37 1.18e-12 Glomerular filtration rate in chronic kidney disease; LIHC cis rs9911578 1.000 rs4372750 chr17:57013803 A/C cg12560992 chr17:57184187 TRIM37 -0.98 -17.78 -0.69 1.58e-50 Intelligence (multi-trait analysis); LIHC cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg13395646 chr4:1353034 KIAA1530 -0.5 -8.33 -0.41 1.94e-15 Obesity-related traits; LIHC cis rs4073582 0.595 rs10896104 chr11:66001869 C/T cg14036092 chr11:66035641 RAB1B 0.45 6.62 0.34 1.36e-10 Gout; LIHC cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg08888203 chr3:10149979 C3orf24 0.56 6.46 0.33 3.55e-10 Alzheimer's disease; LIHC cis rs4803468 0.967 rs2304243 chr19:41942708 C/G cg09537434 chr19:41945824 ATP5SL 1.01 20.35 0.74 6.81e-61 Height; LIHC cis rs8067354 0.645 rs2645467 chr17:57854783 C/T cg02344993 chr17:57696989 CLTC 0.69 11.63 0.53 1.44e-26 Hemoglobin concentration; LIHC cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg23758822 chr17:41437982 NA 0.94 17.95 0.7 3.1e-51 Menopause (age at onset); LIHC cis rs2153535 0.580 rs6597326 chr6:8482019 A/C cg23788917 chr6:8435910 SLC35B3 0.59 8.33 0.41 1.92e-15 Motion sickness; LIHC cis rs3862260 0.509 rs3795663 chr1:120165187 G/A cg16322792 chr1:120165303 ZNF697 0.52 9.46 0.46 5.04e-19 Systemic lupus erythematosus; LIHC cis rs17780086 0.529 rs7406406 chr17:30220153 T/G cg13647721 chr17:30228624 UTP6 0.77 8.87 0.43 4.05e-17 Height; LIHC cis rs1355223 0.902 rs1578622 chr11:34725915 A/G cg11058730 chr11:34937778 PDHX;APIP -0.46 -6.43 -0.33 4.36e-10 Systemic lupus erythematosus and Systemic sclerosis; LIHC cis rs17428076 0.874 rs17615262 chr2:172683481 A/C cg13550731 chr2:172543902 DYNC1I2 0.37 6.0 0.31 5.01e-9 Myopia; LIHC cis rs10463316 0.817 rs7709507 chr5:150783349 C/T cg03212797 chr5:150827313 SLC36A1 -0.4 -5.94 -0.31 7.07e-9 Metabolite levels (Pyroglutamine); LIHC cis rs34779708 0.966 rs12775759 chr10:35400183 G/T cg04310649 chr10:35416472 CREM -0.44 -5.99 -0.31 5.46e-9 Inflammatory bowel disease;Crohn's disease; LIHC cis rs2404602 0.692 rs7163397 chr15:76940315 A/G cg03037974 chr15:76606532 NA 0.75 14.54 0.62 1.28e-37 Blood metabolite levels; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg03038835 chr20:61810902 NA 0.59 7.7 0.38 1.44e-13 Hepatitis; LIHC cis rs8141529 0.600 rs739196 chr22:29311271 G/A cg15103426 chr22:29168792 CCDC117 0.44 6.07 0.31 3.46e-9 Lymphocyte counts; LIHC cis rs67311347 0.911 rs6775936 chr3:40377399 T/G cg24209194 chr3:40518798 ZNF619 0.47 6.68 0.34 9.85e-11 Renal cell carcinoma; LIHC cis rs2976388 0.578 rs34956412 chr8:143822028 C/T cg24634471 chr8:143751801 JRK -0.43 -5.93 -0.31 7.5e-9 Urinary tract infection frequency; LIHC cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg12311346 chr5:56204834 C5orf35 -0.57 -7.5 -0.38 5.38e-13 Initial pursuit acceleration; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg04873026 chr21:30365177 RNF160 0.43 6.18 0.32 1.85e-9 Migraine with aura; LIHC trans rs12599106 0.584 rs12929704 chr16:34898258 C/A cg26668828 chr6:292823 DUSP22 -0.6 -8.03 -0.4 1.62e-14 Menopause (age at onset); LIHC cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg00166722 chr3:10149974 C3orf24 0.54 6.28 0.32 1.02e-9 Alzheimer's disease; LIHC cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg09060608 chr5:178986726 RUFY1 0.39 5.88 0.3 1e-8 Lung cancer; LIHC cis rs2180341 0.960 rs3756996 chr6:127664258 G/C cg24812749 chr6:127587940 RNF146 1.05 15.54 0.64 1.46e-41 Breast cancer; LIHC cis rs4919087 0.748 rs701815 chr10:98975893 A/C cg25902810 chr10:99078978 FRAT1 -0.52 -6.03 -0.31 4.36e-9 Monocyte count; LIHC cis rs644799 0.930 rs2186782 chr11:95649543 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 16.01 0.65 1.98e-43 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs727505 0.954 rs58618031 chr7:124583896 T/C cg23710748 chr7:124431027 NA -0.33 -5.85 -0.3 1.17e-8 Lewy body disease; LIHC cis rs780096 0.526 rs704791 chr2:27657167 T/C cg18428193 chr2:27665017 KRTCAP3;NRBP1 -0.44 -6.79 -0.34 4.89e-11 Total body bone mineral density; LIHC cis rs61021925 1 rs61021925 chr12:122863659 T/C cg23029597 chr12:123009494 RSRC2 0.39 6.43 0.33 4.41e-10 Schizophrenia; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg25998860 chr5:126853954 PRRC1 0.41 6.4 0.33 5.23e-10 Cognitive function; LIHC cis rs1707322 1.000 rs6695421 chr1:46380207 T/C cg06784218 chr1:46089804 CCDC17 0.34 6.03 0.31 4.19e-9 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs1552244 0.572 rs2054478 chr3:10172211 C/T cg00149659 chr3:10157352 C3orf10 1.13 9.95 0.47 1.16e-20 Alzheimer's disease; LIHC cis rs7927771 0.839 rs59360790 chr11:47669175 T/C cg20135002 chr11:47629003 NA -0.5 -8.54 -0.42 4.57e-16 Subjective well-being; LIHC cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg09359103 chr1:154839909 KCNN3 -0.3 -5.81 -0.3 1.43e-8 Prostate cancer; LIHC cis rs28374715 0.681 rs59000092 chr15:41626148 A/G cg18705301 chr15:41695430 NDUFAF1 -0.98 -13.35 -0.59 4.98e-33 Ulcerative colitis; LIHC cis rs4819052 0.851 rs2236446 chr21:46678985 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.54 8.0 0.4 1.92e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs6430585 0.793 rs11684545 chr2:136539122 G/T cg07305463 chr2:136567211 LCT 0.41 7.68 0.38 1.72e-13 Corneal structure; LIHC cis rs2302190 0.882 rs7209650 chr17:56674905 C/T cg05425664 chr17:57184151 TRIM37 -0.46 -5.75 -0.3 1.98e-8 Vitamin D levels; LIHC cis rs11229555 0.645 rs11229459 chr11:58208025 G/A cg15696309 chr11:58395628 NA -0.65 -7.69 -0.38 1.59e-13 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; LIHC cis rs2832191 0.791 rs2832196 chr21:30497412 G/A cg08807101 chr21:30365312 RNF160 -0.57 -8.9 -0.43 3.44e-17 Dental caries; LIHC cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 7.67 0.38 1.83e-13 Height; LIHC cis rs8014204 0.570 rs7147721 chr14:75186010 A/G cg08847533 chr14:75593920 NEK9 0.35 5.88 0.3 9.67e-9 Caffeine consumption; LIHC cis rs9549367 0.707 rs9549353 chr13:113843427 G/A cg18105134 chr13:113819100 PROZ -0.79 -13.39 -0.59 3.62e-33 Platelet distribution width; LIHC trans rs2243480 1.000 rs160633 chr7:65528228 T/C cg10756647 chr7:56101905 PSPH 1.07 13.4 0.59 3.31e-33 Diabetic kidney disease; LIHC cis rs250677 0.687 rs36048 chr5:148441713 G/C cg12140854 chr5:148520817 ABLIM3 -0.45 -6.17 -0.32 1.97e-9 Breast cancer; LIHC cis rs875971 0.825 rs4587224 chr7:65736182 G/A cg11764359 chr7:65958608 NA -0.85 -15.03 -0.63 1.49e-39 Aortic root size; LIHC cis rs4595586 0.525 rs4441057 chr12:39420620 T/A cg26384229 chr12:38710491 ALG10B 0.5 5.92 0.3 8.03e-9 Morning vs. evening chronotype; LIHC cis rs8192917 0.832 rs9671454 chr14:25102056 G/C cg03875678 chr14:25103546 GZMB 0.4 6.64 0.34 1.27e-10 Vitiligo; LIHC cis rs2839186 0.770 rs2839984 chr21:47671690 A/G cg11766577 chr21:47581405 C21orf56 -0.45 -7.41 -0.37 9.84e-13 Testicular germ cell tumor; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg24780086 chr5:14713043 ANKH 0.41 6.09 0.31 3e-9 Pancreatic cancer; LIHC trans rs2074193 0.585 rs11183915 chr12:47770984 C/T cg06909117 chr11:119205209 RNF26 -0.44 -6.14 -0.32 2.27e-9 Migraine with aura; LIHC cis rs2070488 0.775 rs6599208 chr3:38558104 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.69 -11.36 -0.52 1.42e-25 Electrocardiographic conduction measures; LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg21448741 chr8:58168803 NA 0.35 6.57 0.33 1.85e-10 Developmental language disorder (linguistic errors); LIHC cis rs2303759 0.709 rs10422677 chr19:49824290 C/T cg22590775 chr19:49891494 CCDC155 0.47 7.47 0.37 6.79e-13 Multiple sclerosis; LIHC cis rs13161895 1.000 rs4700853 chr5:179473328 G/A cg06664874 chr5:179499304 RNF130 0.61 7.56 0.38 3.66e-13 LDL cholesterol; LIHC trans rs10242455 0.571 rs45527841 chr7:99310965 C/T cg09045935 chr12:6379348 NA 0.73 6.04 0.31 4.09e-9 Blood metabolite levels; LIHC cis rs9942416 0.660 rs2047059 chr5:75008193 T/C cg19683494 chr5:74908142 NA 0.51 6.93 0.35 2.11e-11 Age-related disease endophenotypes; LIHC cis rs9435341 0.929 rs3108681 chr1:107556493 C/A cg09367891 chr1:107599246 PRMT6 -0.64 -10.19 -0.48 1.82e-21 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs6988636 1.000 rs16898086 chr8:124190445 A/G cg15893493 chr8:124194847 FAM83A 0.85 8.08 0.4 1.14e-14 Urinary uromodulin levels; LIHC cis rs7487075 0.619 rs4768724 chr12:46848416 C/T cg23829395 chr12:46796953 NA 0.35 6.15 0.32 2.11e-9 Itch intensity from mosquito bite; LIHC cis rs7520050 0.966 rs12564541 chr1:46380237 G/A cg03146154 chr1:46216737 IPP -0.38 -6.17 -0.32 1.9e-9 Red blood cell count;Reticulocyte count; LIHC cis rs11724804 0.532 rs73207782 chr4:848764 G/C cg20916646 chr4:852691 GAK 0.65 7.35 0.37 1.46e-12 Primary biliary cholangitis;Limited cutaneous systemic scleroderma; LIHC cis rs7412746 0.634 rs12096831 chr1:150864113 T/G cg17724175 chr1:150552817 MCL1 0.44 8.69 0.43 1.55e-16 Melanoma; LIHC cis rs9868809 0.772 rs12107252 chr3:48691316 T/C cg07636037 chr3:49044803 WDR6 -0.59 -7.09 -0.36 7.58e-12 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; LIHC cis rs2463822 0.748 rs2513038 chr11:62081329 A/C cg06239285 chr11:62104954 ASRGL1 0.93 6.86 0.35 3.16e-11 Chronic obstructive pulmonary disease-related biomarkers; LIHC cis rs507080 0.885 rs693037 chr11:118553326 C/T cg04173919 chr11:118528438 PHLDB1 0.35 6.4 0.33 5.16e-10 Serum metabolite levels; LIHC cis rs11098499 1.000 rs58601355 chr4:120186367 T/C cg09307838 chr4:120376055 NA 0.7 10.33 0.49 5.97e-22 Corneal astigmatism; LIHC cis rs4746818 1.000 rs6480383 chr10:70890482 C/T cg11621586 chr10:70884670 VPS26A 0.88 14.57 0.62 1e-37 Left atrial antero-posterior diameter; LIHC cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg04013166 chr16:89971882 TCF25 0.61 8.52 0.42 5.25e-16 Skin colour saturation; LIHC cis rs7208859 0.623 rs3752019 chr17:29151705 C/T cg14067834 chr17:29058358 SUZ12P 0.69 6.69 0.34 9.41e-11 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs600806 0.778 rs4970765 chr1:110009171 C/T cg11161837 chr1:110010384 SYPL2 0.46 6.3 0.32 9.14e-10 Intelligence (multi-trait analysis); LIHC cis rs9733 0.519 rs6700022 chr1:150670484 G/T cg13175981 chr1:150552382 MCL1 0.41 5.78 0.3 1.68e-8 Tonsillectomy; LIHC cis rs9381040 0.655 rs9381029 chr6:41026453 G/C cg04346459 chr6:41068666 NFYA;LOC221442 -0.38 -5.98 -0.31 5.51e-9 Alzheimer's disease (late onset); LIHC cis rs2282032 0.527 rs60971518 chr14:90765745 A/G cg04374321 chr14:90722782 PSMC1 0.49 7.07 0.36 8.56e-12 Longevity; LIHC trans rs2727020 0.664 rs4929893 chr11:49196332 C/T cg03929089 chr4:120376271 NA -0.79 -13.87 -0.6 5.12e-35 Coronary artery disease; LIHC cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg09455208 chr3:40491958 NA 0.38 7.6 0.38 2.96e-13 Renal cell carcinoma; LIHC cis rs17376456 0.877 rs13173952 chr5:93307557 A/T cg25358565 chr5:93447407 FAM172A 1.11 10.19 0.48 1.8e-21 Diabetic retinopathy; LIHC cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs61990749 0.597 rs176980 chr14:78198449 C/G cg21497246 chr14:78225524 SNW1;C14orf178 0.5 7.75 0.39 1.07e-13 Fibroblast growth factor basic levels; LIHC cis rs12142240 0.698 rs6659228 chr1:46811027 C/G cg00530320 chr1:46809349 NSUN4 0.52 5.78 0.3 1.71e-8 Menopause (age at onset); LIHC cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg11062466 chr8:58055876 NA 0.47 6.39 0.33 5.48e-10 Developmental language disorder (linguistic errors); LIHC trans rs1814175 0.645 rs12364337 chr11:49942580 A/T cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC trans rs1005277 0.505 rs1208689 chr10:38097775 C/G cg17830980 chr10:43048298 ZNF37B -0.46 -8.97 -0.44 2.04e-17 Extrinsic epigenetic age acceleration; LIHC trans rs1814175 0.935 rs1827017 chr11:49632592 C/G cg03929089 chr4:120376271 NA -0.88 -17.24 -0.68 2.31e-48 Height; LIHC cis rs8180040 0.691 rs12489211 chr3:47221451 T/A cg27129171 chr3:47204927 SETD2 0.69 12.17 0.55 1.52e-28 Colorectal cancer; LIHC cis rs7829975 0.514 rs2976929 chr8:8258712 T/C cg14343924 chr8:8086146 FLJ10661 0.41 5.81 0.3 1.4e-8 Mood instability; LIHC cis rs4820294 1.000 rs7291867 chr22:38062112 C/G cg26138144 chr22:38071188 LGALS1 0.76 14.04 0.6 1.15e-35 Fat distribution (HIV); LIHC cis rs6424115 0.729 rs586173 chr1:24055718 A/G cg10978503 chr1:24200527 CNR2 -0.29 -6.96 -0.35 1.7e-11 Immature fraction of reticulocytes; LIHC trans rs75804782 0.581 rs13415491 chr2:239319901 C/T cg01134436 chr17:81009848 B3GNTL1 0.82 6.62 0.34 1.41e-10 Morning vs. evening chronotype;Chronotype; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg00090800 chr16:27325237 IL4R 0.43 6.51 0.33 2.72e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs951366 0.764 rs708724 chr1:205743663 A/C cg07167872 chr1:205819463 PM20D1 0.59 8.61 0.42 2.79e-16 Menarche (age at onset); LIHC cis rs2576037 0.583 rs512699 chr18:44374681 C/T cg20875182 chr18:44561130 TCEB3B;KATNAL2 -0.69 -10.92 -0.51 5.28e-24 Personality dimensions; LIHC cis rs763121 0.853 rs4821816 chr22:39113134 G/A cg14440974 chr22:39074834 NA -0.36 -5.9 -0.3 8.79e-9 Menopause (age at onset); LIHC cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg03874509 chr1:107600012 PRMT6 -0.72 -11.21 -0.52 4.74e-25 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs614226 0.516 rs1794748 chr12:120953758 A/G cg01236616 chr12:121019343 POP5 1.25 19.27 0.72 1.53e-56 Type 1 diabetes nephropathy; LIHC cis rs507080 0.501 rs516503 chr11:118580348 C/T cg04173919 chr11:118528438 PHLDB1 0.31 5.79 0.3 1.6e-8 Serum metabolite levels; LIHC cis rs10464366 0.544 rs4723824 chr7:39153698 T/C cg15212455 chr7:39170539 POU6F2 0.47 8.37 0.41 1.53e-15 IgG glycosylation; LIHC cis rs8067354 0.574 rs1295923 chr17:57960436 A/G cg13753209 chr17:57696993 CLTC 0.7 10.42 0.49 3.02e-22 Hemoglobin concentration; LIHC cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg11494091 chr17:61959527 GH2 0.46 8.24 0.41 3.65e-15 Prudent dietary pattern; LIHC trans rs11992162 1.000 rs7460395 chr8:11835375 C/T cg19442470 chr8:27470225 CLU -0.37 -6.38 -0.33 5.82e-10 Monocyte count; LIHC trans rs916888 0.779 rs199528 chr17:44843136 C/T cg22968622 chr17:43663579 NA 1.2 12.94 0.57 1.93e-31 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg04944784 chr2:26401820 FAM59B 0.71 9.07 0.44 9.7e-18 Gut microbiome composition (summer); LIHC cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg09323728 chr8:95962352 TP53INP1 -0.3 -6.5 -0.33 2.82e-10 Type 2 diabetes; LIHC cis rs9325144 0.555 rs6582576 chr12:38701230 C/T cg26384229 chr12:38710491 ALG10B -0.56 -7.8 -0.39 7.8e-14 Morning vs. evening chronotype; LIHC cis rs4407350 0.901 rs5765717 chr22:44917646 G/T cg11695653 chr22:44894386 LDOC1L -0.37 -6.23 -0.32 1.36e-9 Intelligence (multi-trait analysis); LIHC trans rs12753920 0.671 rs4437922 chr1:92581818 C/T cg15668468 chr10:118892869 VAX1 -0.41 -6.35 -0.32 6.85e-10 Systemic lupus erythematosus; LIHC cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.55 8.75 0.43 9.63e-17 Schizophrenia; LIHC cis rs7216064 1.000 rs8081517 chr17:65845697 A/T cg12091567 chr17:66097778 LOC651250 -0.66 -9.65 -0.46 1.23e-19 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; LIHC cis rs10791097 0.694 rs10894275 chr11:130756251 C/T cg14779329 chr11:130786720 SNX19 0.42 6.34 0.32 7.1e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs10744422 0.858 rs2292136 chr12:123339344 A/G cg22842854 chr12:123319900 HIP1R -0.74 -9.83 -0.47 2.99e-20 Schizophrenia; LIHC cis rs67478160 0.643 rs11628332 chr14:104241141 C/T cg01849466 chr14:104193079 ZFYVE21 -0.46 -7.63 -0.38 2.43e-13 Schizophrenia; LIHC cis rs7249142 0.549 rs1858846 chr19:19281187 T/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.36 -6.01 -0.31 4.79e-9 IgG glycosylation; LIHC cis rs2180341 1.000 rs6910763 chr6:127630925 T/C cg27446573 chr6:127587934 RNF146 1.03 16.06 0.66 1.17e-43 Breast cancer; LIHC cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg02782426 chr3:40428986 ENTPD3 0.34 6.38 0.33 5.71e-10 Renal cell carcinoma; LIHC cis rs4742903 0.935 rs10820602 chr9:106861282 C/T cg14250997 chr9:106856677 SMC2 0.42 7.45 0.37 7.54e-13 High-grade serous ovarian cancer;Breast cancer; LIHC cis rs2836974 0.666 rs12626405 chr21:40663121 G/T cg17971929 chr21:40555470 PSMG1 -0.47 -7.1 -0.36 7.48e-12 Cognitive function; LIHC trans rs35110281 0.548 rs2838350 chr21:45109972 T/C cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.06 0.31 3.61e-9 Mean corpuscular volume; LIHC cis rs1559088 0.948 rs12608825 chr19:33581219 C/T cg27124370 chr19:33622961 WDR88 -0.54 -8.61 -0.42 2.74e-16 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs6582630 0.562 rs35080195 chr12:38310866 G/A cg26384229 chr12:38710491 ALG10B -0.44 -5.75 -0.3 2.03e-8 Drug-induced liver injury (flucloxacillin); LIHC cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg09455208 chr3:40491958 NA 0.39 7.94 0.39 2.94e-14 Renal cell carcinoma; LIHC cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg05590025 chr7:65112418 INTS4L2 -0.64 -6.95 -0.35 1.85e-11 Diabetic kidney disease; LIHC cis rs2758596 0.826 rs2758602 chr1:156198232 T/G cg25208724 chr1:156163844 SLC25A44 0.74 7.77 0.39 9.34e-14 Paclitaxel disposition in epithelial ovarian cancer; LIHC cis rs9902453 0.967 rs55748380 chr17:28469782 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 8.87 0.43 4.04e-17 Coffee consumption (cups per day); LIHC cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 11.34 0.52 1.6e-25 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs12497850 0.931 rs6446253 chr3:48911443 C/T cg06212747 chr3:49208901 KLHDC8B 0.57 7.36 0.37 1.42e-12 Parkinson's disease; LIHC cis rs11098499 0.955 rs1511019 chr4:120166007 T/G cg09307838 chr4:120376055 NA 0.74 10.97 0.51 3.37e-24 Corneal astigmatism; LIHC cis rs7666738 0.515 rs10015315 chr4:98700137 A/G cg05340658 chr4:99064831 C4orf37 0.49 6.44 0.33 4.14e-10 Colonoscopy-negative controls vs population controls; LIHC cis rs6912958 0.712 rs2754262 chr6:88405585 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.41 -7.03 -0.36 1.14e-11 Monocyte percentage of white cells; LIHC cis rs208520 1.000 rs12200490 chr6:66976084 G/A cg07460842 chr6:66804631 NA 0.69 7.34 0.37 1.54e-12 Exhaled nitric oxide output; LIHC cis rs6456156 0.586 rs9457266 chr6:167482555 T/C cg07741184 chr6:167504864 NA 0.27 6.27 0.32 1.08e-9 Primary biliary cholangitis; LIHC cis rs1669338 0.507 rs4685609 chr3:3202279 T/C cg16797762 chr3:3221439 CRBN -0.85 -7.58 -0.38 3.36e-13 White matter integrity; LIHC cis rs11671005 0.735 rs12986387 chr19:58927215 C/T cg25952890 chr19:58913133 NA 0.7 7.46 0.37 7.39e-13 Mean platelet volume; LIHC cis rs9649213 0.593 rs12728 chr7:97922851 C/T cg08684580 chr7:98029266 BAIAP2L1 -0.4 -6.21 -0.32 1.56e-9 Prostate cancer (SNP x SNP interaction); LIHC cis rs8027181 0.797 rs8033580 chr15:72994968 C/A cg25996835 chr15:72978165 BBS4;HIGD2B 0.49 7.64 0.38 2.14e-13 Triglyceride levels; LIHC cis rs13382862 0.895 rs13385499 chr2:20882413 A/G cg27141850 chr2:20869434 GDF7 -0.36 -6.83 -0.35 3.82e-11 Abdominal aortic aneurysm; LIHC cis rs7572733 0.534 rs11890137 chr2:198816662 G/A cg00792783 chr2:198669748 PLCL1 0.47 6.9 0.35 2.58e-11 Dermatomyositis; LIHC cis rs1800813 0.515 rs34148754 chr4:55057049 G/A cg17187183 chr4:55093834 PDGFRA 0.51 6.79 0.34 4.93e-11 Corneal curvature; LIHC cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg13866156 chr1:1669148 SLC35E2 -0.7 -13.11 -0.58 4.12e-32 Body mass index; LIHC cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg07061783 chr6:25882402 NA -0.47 -6.53 -0.33 2.38e-10 Blood metabolite levels; LIHC cis rs2439831 0.850 rs2439832 chr15:43779686 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.79 13.54 0.59 9.52e-34 Lung cancer in ever smokers; LIHC cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg08280861 chr8:58055591 NA 0.51 5.74 0.3 2.11e-8 Developmental language disorder (linguistic errors); LIHC cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg12463550 chr7:65579703 CRCP 0.67 6.99 0.35 1.48e-11 Diabetic kidney disease; LIHC cis rs611744 0.647 rs1457211 chr8:109261318 C/T cg21045802 chr8:109455806 TTC35 -0.6 -10.38 -0.49 4.16e-22 Dupuytren's disease; LIHC cis rs12477438 0.765 rs4374423 chr2:99662348 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.51 -8.39 -0.41 1.33e-15 Chronic sinus infection; LIHC cis rs2522056 1.000 rs7730247 chr5:131781288 A/C cg24060327 chr5:131705240 SLC22A5 0.61 8.4 0.41 1.18e-15 Lymphocyte counts;Fibrinogen; LIHC cis rs7246657 0.941 rs10418729 chr19:37737065 A/C cg23950597 chr19:37808831 NA -0.5 -6.33 -0.32 7.65e-10 Coronary artery calcification; LIHC trans rs11098499 0.909 rs11098530 chr4:120413154 C/T cg25214090 chr10:38739885 LOC399744 0.57 9.44 0.45 6.19e-19 Corneal astigmatism; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg27054308 chr14:20922865 APEX1;OSGEP 0.5 7.23 0.36 3.22e-12 Pancreatic cancer; LIHC cis rs7772486 0.875 rs1412080 chr6:146417304 T/C cg05347473 chr6:146136440 FBXO30 0.35 5.75 0.3 2.01e-8 Lobe attachment (rater-scored or self-reported); LIHC cis rs7909074 0.966 rs4268464 chr10:45401081 T/A cg04218760 chr10:45406644 TMEM72 -0.21 -6.63 -0.34 1.27e-10 Mean corpuscular volume; LIHC cis rs77106637 0.556 rs7123876 chr11:72444583 T/C cg03713592 chr11:72463424 ARAP1 0.59 6.74 0.34 6.85e-11 Type 2 diabetes; LIHC trans rs1010366 0.522 rs9648103 chr7:7245268 A/T cg09946346 chr11:65244890 NA -0.47 -6.17 -0.32 1.96e-9 Systolic blood pressure; LIHC cis rs11098499 0.754 rs66900435 chr4:120249425 C/A cg09307838 chr4:120376055 NA 0.71 11.15 0.52 7.7e-25 Corneal astigmatism; LIHC cis rs2439831 1.000 rs2256764 chr15:43735763 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.63 7.89 0.39 4.24e-14 Lung cancer in ever smokers; LIHC cis rs12478296 1.000 rs55814222 chr2:243041166 C/T cg18898632 chr2:242989856 NA -0.58 -7.84 -0.39 5.85e-14 Obesity-related traits; LIHC cis rs1348850 0.747 rs1047884 chr2:178488281 C/G cg27490568 chr2:178487706 NA 0.39 6.01 0.31 4.77e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs67478160 0.634 rs1955660 chr14:104229985 C/T cg01849466 chr14:104193079 ZFYVE21 -0.49 -8.36 -0.41 1.64e-15 Schizophrenia; LIHC cis rs1185460 0.547 rs666741 chr11:118911350 A/C cg23280166 chr11:118938394 VPS11 -0.44 -6.06 -0.31 3.62e-9 Coronary artery disease; LIHC cis rs2576037 0.583 rs487386 chr18:44377004 A/G cg20875182 chr18:44561130 TCEB3B;KATNAL2 0.66 9.96 0.47 1.12e-20 Personality dimensions; LIHC cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg08219700 chr8:58056026 NA 0.52 7.11 0.36 6.68e-12 Developmental language disorder (linguistic errors); LIHC cis rs2153535 0.580 rs6597334 chr6:8504779 C/T cg07606381 chr6:8435919 SLC35B3 0.8 11.83 0.54 2.74e-27 Motion sickness; LIHC cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg02290350 chr8:58132656 NA 0.41 8.52 0.42 5.29e-16 Developmental language disorder (linguistic errors); LIHC cis rs9788682 0.948 rs59683676 chr15:78833453 T/C cg06917634 chr15:78832804 PSMA4 -0.55 -7.78 -0.39 8.9e-14 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs72627123 0.867 rs8020310 chr14:74494437 A/G cg12022184 chr14:74485813 ENTPD5;C14orf45 0.91 9.6 0.46 1.73e-19 Morning vs. evening chronotype; LIHC cis rs9814567 1.000 rs9289478 chr3:134268619 A/G cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.98 -0.31 5.76e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs912057 0.585 rs1745341 chr6:6744990 T/C cg06612196 chr6:6737390 NA 0.51 9.54 0.46 2.81e-19 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); LIHC cis rs782590 0.807 rs782572 chr2:55912120 T/C cg18811423 chr2:55921094 PNPT1 0.94 15.33 0.64 1.01e-40 Metabolic syndrome; LIHC cis rs2239547 0.657 rs6445538 chr3:52874288 T/C cg11645453 chr3:52864694 ITIH4 0.36 9.32 0.45 1.44e-18 Schizophrenia; LIHC cis rs2180341 1.000 rs4897207 chr6:127605898 C/T cg24812749 chr6:127587940 RNF146 1.06 15.96 0.65 2.91e-43 Breast cancer; LIHC cis rs1163251 0.902 rs839605 chr1:120217524 C/A cg19096424 chr1:120255104 PHGDH 0.62 7.83 0.39 6.23e-14 Blood metabolite levels; LIHC cis rs11098499 0.738 rs34566984 chr4:120361270 G/A cg09307838 chr4:120376055 NA 0.78 12.32 0.55 4.08e-29 Corneal astigmatism; LIHC cis rs6582630 0.519 rs4436613 chr12:38293653 T/C cg26384229 chr12:38710491 ALG10B 0.59 8.13 0.4 7.95e-15 Drug-induced liver injury (flucloxacillin); LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14001360 chr2:28113654 BRE;LOC100302650;RBKS -0.38 -6.24 -0.32 1.27e-9 Pancreatic cancer; LIHC cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.95 -10.5 -0.49 1.5e-22 Platelet count; LIHC cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg09904177 chr6:26538194 HMGN4 0.56 11.27 0.52 2.89e-25 Intelligence (multi-trait analysis); LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg08219700 chr8:58056026 NA 0.51 7.01 0.35 1.28e-11 Developmental language disorder (linguistic errors); LIHC cis rs35883536 0.967 rs1582091 chr1:101177133 G/T cg14515779 chr1:101123966 NA -0.66 -12.35 -0.56 3.07e-29 Monocyte count; LIHC cis rs2204008 0.744 rs11181337 chr12:38322083 C/A cg26384229 chr12:38710491 ALG10B 0.58 8.16 0.4 6.58e-15 Bladder cancer; LIHC cis rs9916302 0.706 rs3744349 chr17:37414842 C/T cg07936489 chr17:37558343 FBXL20 -0.84 -12.01 -0.54 5.99e-28 Glomerular filtration rate (creatinine); LIHC cis rs1008375 1.000 rs2109522 chr4:17658645 T/A cg16339924 chr4:17578868 LAP3 0.45 6.35 0.32 6.94e-10 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs11696845 0.666 rs13042905 chr20:43379454 T/C cg25301532 chr20:43378953 KCNK15 0.26 6.1 0.31 2.87e-9 Obesity-related traits; LIHC cis rs892961 0.932 rs12453822 chr17:75416792 G/A cg01320579 chr17:75405842 SEPT9 0.52 7.2 0.36 3.88e-12 Airflow obstruction; LIHC cis rs3768617 0.966 rs10797850 chr1:183094802 G/A ch.1.3577855R chr1:183094577 LAMC1 0.48 7.66 0.38 1.95e-13 Fuchs's corneal dystrophy; LIHC cis rs4853012 0.887 rs77148265 chr2:74339519 C/T cg19729930 chr2:74357872 NA 0.81 16.94 0.68 3.68e-47 Gestational age at birth (maternal effect); LIHC cis rs3008870 0.727 rs2755270 chr1:67474503 C/T cg02640540 chr1:67518911 SLC35D1 0.44 6.83 0.35 3.83e-11 Lymphocyte percentage of white cells; LIHC cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg04025307 chr7:1156635 C7orf50 0.67 11.9 0.54 1.52e-27 Longevity;Endometriosis; LIHC cis rs1707322 0.681 rs12048866 chr1:46117492 T/G cg06784218 chr1:46089804 CCDC17 0.41 7.49 0.38 5.82e-13 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs10220309 0.513 rs2371149 chr14:80587622 A/T cg00705661 chr14:93706609 BTBD7 0.55 6.61 0.34 1.44e-10 Lung function (FEV1); LIHC cis rs939574 1.000 rs3817424 chr2:220096903 A/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.99 10.61 0.5 6.36e-23 Platelet distribution width; LIHC cis rs1552244 0.554 rs13081079 chr3:10056348 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -7.57 -0.38 3.57e-13 Alzheimer's disease; LIHC cis rs4319547 1.000 rs7309390 chr12:123110422 A/G cg05707623 chr12:122985044 ZCCHC8 -0.57 -7.6 -0.38 2.85e-13 Body mass index; LIHC cis rs4148883 0.713 rs3828541 chr4:100042262 A/G cg12011299 chr4:100065546 ADH4 0.37 7.41 0.37 1.02e-12 Alcohol dependence; LIHC cis rs10193935 1.000 rs12618105 chr2:42414146 T/G cg27598129 chr2:42591480 NA -0.73 -11.01 -0.51 2.42e-24 Colonoscopy-negative controls vs population controls; LIHC cis rs4638749 0.677 rs1522021 chr2:108833263 C/T cg06795125 chr2:108905320 SULT1C2 -0.3 -6.02 -0.31 4.52e-9 Blood pressure; LIHC cis rs11969893 0.850 rs3734351 chr6:101307131 C/T cg12253828 chr6:101329408 ASCC3 1.04 13.12 0.58 3.79e-32 Economic and political preferences (immigration/crime); LIHC cis rs2952156 0.652 rs11869286 chr17:37813856 C/G cg07936489 chr17:37558343 FBXL20 -0.44 -6.6 -0.34 1.6e-10 Asthma; LIHC cis rs35110281 0.712 rs1454648 chr21:45053815 C/T cg01579765 chr21:45077557 HSF2BP -0.33 -6.23 -0.32 1.36e-9 Mean corpuscular volume; LIHC cis rs17213078 0.505 rs3795909 chr2:106754734 A/G cg16099169 chr2:106886729 NA 0.4 6.13 0.31 2.37e-9 Facial morphology (factor 23); LIHC cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg06238570 chr21:40685208 BRWD1 -0.52 -8.42 -0.41 1.08e-15 Cognitive function; LIHC cis rs9457247 1.000 rs430097 chr6:167405073 A/G cg23791538 chr6:167370224 RNASET2 -0.65 -11.11 -0.52 1.05e-24 Crohn's disease; LIHC cis rs12701220 0.503 rs12702024 chr7:1129820 G/C cg02733842 chr7:1102375 C7orf50 -0.77 -8.02 -0.4 1.65e-14 Bronchopulmonary dysplasia; LIHC cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg24209194 chr3:40518798 ZNF619 -0.46 -6.86 -0.35 3.23e-11 Renal cell carcinoma; LIHC trans rs2270927 0.510 rs10942765 chr5:75591324 G/A cg13563193 chr19:33072644 PDCD5 0.97 9.09 0.44 8.14e-18 Mean corpuscular volume; LIHC cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg02782426 chr3:40428986 ENTPD3 0.32 6.06 0.31 3.6e-9 Renal cell carcinoma; LIHC cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg06481639 chr22:41940642 POLR3H 0.68 6.95 0.35 1.89e-11 Vitiligo; LIHC cis rs10504229 0.815 rs16921955 chr8:58164553 C/T cg21724239 chr8:58056113 NA 0.45 6.0 0.31 5.12e-9 Developmental language disorder (linguistic errors); LIHC cis rs2737618 0.651 rs2248967 chr1:200084893 A/G cg21825944 chr1:200113062 NR5A2 0.46 7.86 0.39 5.02e-14 Uric acid levels; LIHC cis rs6499255 0.904 rs2161631 chr16:69556948 C/A cg15192750 chr16:69999425 NA 0.44 6.56 0.33 2.04e-10 IgE levels; LIHC cis rs7131987 0.650 rs10843377 chr12:29437053 C/G cg05697976 chr12:29376483 FAR2 -0.3 -5.87 -0.3 1.02e-8 QT interval; LIHC cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.93 9.08 0.44 8.96e-18 Platelet count; LIHC cis rs2839627 0.561 rs7281655 chr21:44269743 A/G cg18192155 chr21:44258298 NA 0.44 7.0 0.35 1.34e-11 Information processing speed; LIHC trans rs6876348 0.520 rs9327495 chr5:128202113 A/G cg11199428 chr13:52027379 INTS6 0.47 6.51 0.33 2.72e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs6750047 0.747 rs2116229 chr2:38270490 G/T cg07380506 chr2:38303506 CYP1B1 0.52 6.18 0.32 1.84e-9 Cutaneous malignant melanoma;Melanoma; LIHC cis rs921968 0.643 rs613539 chr2:219455967 G/T cg17980119 chr2:219472607 PLCD4 0.34 5.86 0.3 1.06e-8 Mean corpuscular hemoglobin concentration; LIHC cis rs10876993 0.890 rs774887 chr12:58034835 A/G cg18357645 chr12:58087776 OS9 0.5 8.13 0.4 8.02e-15 Celiac disease or Rheumatoid arthritis; LIHC cis rs7412746 0.611 rs4970984 chr1:150887377 T/C cg17724175 chr1:150552817 MCL1 0.39 7.64 0.38 2.24e-13 Melanoma; LIHC cis rs62380364 0.602 rs11743441 chr5:88065637 G/T cg22951263 chr5:87985283 NA -0.43 -7.2 -0.36 3.82e-12 Intelligence (multi-trait analysis); LIHC cis rs7264396 0.790 rs12480622 chr20:34234620 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.63 -9.56 -0.46 2.47e-19 Total cholesterol levels; LIHC cis rs2204008 0.715 rs11514342 chr12:38236710 T/A cg13010199 chr12:38710504 ALG10B 0.5 5.83 0.3 1.26e-8 Bladder cancer; LIHC cis rs2963155 0.590 rs258757 chr5:142620736 A/G cg17617527 chr5:142782415 NR3C1 -0.87 -9.66 -0.46 1.13e-19 Breast cancer; LIHC cis rs6840360 0.615 rs12647465 chr4:152607318 C/A cg22705602 chr4:152727874 NA -0.32 -6.72 -0.34 7.74e-11 Intelligence (multi-trait analysis); LIHC cis rs4332037 0.901 rs7791899 chr7:1935988 T/C cg23422044 chr7:1970798 MAD1L1 -0.64 -7.26 -0.37 2.57e-12 Bipolar disorder; LIHC cis rs644799 0.601 rs662168 chr11:95586982 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.62 9.59 0.46 1.91e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs35883536 0.588 rs955337 chr1:101108834 A/T cg14515779 chr1:101123966 NA -0.59 -11.16 -0.52 7e-25 Monocyte count; LIHC cis rs9915021 0.623 rs9913875 chr17:33939655 A/C cg20932281 chr17:33905541 PEX12 0.57 7.06 0.36 9.29e-12 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; LIHC cis rs1862618 0.671 rs2591964 chr5:56236900 T/G cg12311346 chr5:56204834 C5orf35 0.46 6.22 0.32 1.45e-9 Initial pursuit acceleration; LIHC trans rs61931739 0.534 rs1705757 chr12:34091637 A/G cg26384229 chr12:38710491 ALG10B 0.44 6.25 0.32 1.24e-9 Morning vs. evening chronotype; LIHC cis rs4888262 0.526 rs7205258 chr16:74642539 C/T cg01733217 chr16:74700730 RFWD3 0.86 16.68 0.67 4.12e-46 Testicular germ cell tumor; LIHC cis rs7131987 0.650 rs4331146 chr12:29440083 G/T cg00204748 chr12:29376779 FAR2 0.39 7.35 0.37 1.46e-12 QT interval; LIHC cis rs6121246 0.954 rs6058470 chr20:30416827 A/T cg13852791 chr20:30311386 BCL2L1 0.92 9.45 0.45 5.63e-19 Mean corpuscular hemoglobin; LIHC cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.49 6.64 0.34 1.25e-10 Bipolar disorder; LIHC cis rs9381040 0.655 rs879491 chr6:41026953 A/G cg04346459 chr6:41068666 NFYA;LOC221442 -0.41 -6.42 -0.33 4.67e-10 Alzheimer's disease (late onset); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg02051553 chr1:10044519 NMNAT1 0.37 6.27 0.32 1.1e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs589448 0.902 rs315124 chr12:69771727 G/A cg19645103 chr12:69753606 YEATS4 -0.4 -5.96 -0.31 6.15e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs4555082 0.874 rs11622166 chr14:105759763 C/A cg13114125 chr14:105738426 BRF1 -0.8 -10.07 -0.48 4.54e-21 Mean platelet volume;Platelet distribution width; LIHC cis rs2806561 0.796 rs1738467 chr1:23506521 C/T cg19743168 chr1:23544995 NA 0.36 6.11 0.31 2.75e-9 Height; LIHC trans rs9356009 0.892 rs3792929 chr6:158264395 C/A cg16165903 chr3:32023351 ZNF860;OSBPL10 0.59 6.17 0.32 1.98e-9 Lipoprotein (a) - cholesterol levels; LIHC cis rs9427116 0.502 rs9426830 chr1:154594690 A/G cg17218026 chr1:154582156 ADAR 0.36 7.0 0.35 1.38e-11 Blood protein levels; LIHC cis rs922107 0.713 rs4658190 chr1:89943585 G/A cg15422784 chr1:90023713 LRRC8B 0.45 7.07 0.36 8.74e-12 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.48 7.75 0.39 1.03e-13 Prudent dietary pattern; LIHC cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg11764359 chr7:65958608 NA -0.58 -6.08 -0.31 3.14e-9 Diabetic kidney disease; LIHC cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg18252515 chr7:66147081 NA 1.29 17.4 0.69 4.95e-49 Diabetic kidney disease; LIHC cis rs7131987 0.903 rs2216853 chr12:29413248 C/G cg16970926 chr12:29381810 FAR2 0.32 6.8 0.34 4.75e-11 QT interval; LIHC cis rs9378688 1.000 rs3800190 chr6:2229054 T/C cg12303981 chr6:2244766 GMDS -0.49 -6.22 -0.32 1.48e-9 Caudate nucleus volume; LIHC trans rs6578985 0.714 rs11042628 chr11:2124902 G/T cg20230732 chr3:128721448 CCDC48 0.37 6.09 0.31 3.05e-9 Femoral neck bone geometry and menarche (age at onset); LIHC cis rs7520050 0.966 rs4660910 chr1:46548402 G/T cg03146154 chr1:46216737 IPP -0.38 -6.21 -0.32 1.51e-9 Red blood cell count;Reticulocyte count; LIHC cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg12373951 chr3:133503437 NA 0.73 13.2 0.58 1.87e-32 Iron status biomarkers; LIHC cis rs950776 0.506 rs12915366 chr15:78831753 G/A cg06917634 chr15:78832804 PSMA4 0.95 14.37 0.61 5.73e-37 Sudden cardiac arrest; LIHC cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg25364880 chr3:44379878 C3orf23 0.47 6.64 0.34 1.25e-10 Depressive symptoms; LIHC cis rs67478160 0.634 rs2144080 chr14:104258761 A/C cg08213375 chr14:104286397 PPP1R13B 0.53 9.99 0.48 8.39e-21 Schizophrenia; LIHC cis rs600626 0.529 rs11236527 chr11:75469310 A/G cg24262691 chr11:75473276 NA -0.45 -6.65 -0.34 1.16e-10 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); LIHC cis rs7246657 0.882 rs6508716 chr19:37819010 T/C cg23950597 chr19:37808831 NA -0.44 -5.94 -0.31 6.86e-9 Coronary artery calcification; LIHC cis rs7075426 1.000 rs10887609 chr10:88206702 C/T cg07322936 chr10:88137208 NA -0.5 -7.2 -0.36 3.84e-12 Migraine without aura; LIHC cis rs9399137 0.507 rs6940878 chr6:135366309 G/A cg24558204 chr6:135376177 HBS1L 0.65 10.96 0.51 3.63e-24 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; LIHC cis rs6998277 1.000 rs35155104 chr8:103646559 G/T cg10187029 chr8:103597600 NA 0.76 9.06 0.44 1.03e-17 Migraine; LIHC cis rs4917300 0.626 rs28375965 chr8:143103882 A/G cg25363559 chr8:143086065 NA -0.26 -8.27 -0.41 2.96e-15 Amyotrophic lateral sclerosis; LIHC cis rs10791097 0.694 rs10160281 chr11:130742788 T/C cg09137382 chr11:130731461 NA 0.4 6.03 0.31 4.16e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4665809 0.549 rs3828255 chr2:26413252 G/A cg08067268 chr2:26466485 HADHB;HADHA 0.48 6.0 0.31 5.03e-9 Gut microbiome composition (summer); LIHC cis rs6089829 0.962 rs4809455 chr20:61660781 G/C cg03213289 chr20:61660250 NA 0.51 9.1 0.44 7.55e-18 Prostate cancer (SNP x SNP interaction); LIHC cis rs7552404 0.960 rs12085123 chr1:76149749 G/A cg03433033 chr1:76189801 ACADM 0.67 9.44 0.45 5.91e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs9303401 0.659 rs72828726 chr17:56951217 C/G cg25039879 chr17:56429692 SUPT4H1 0.79 8.92 0.43 2.81e-17 Cognitive test performance; LIHC cis rs6060717 0.610 rs2590964 chr20:34613376 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.48 -8.06 -0.4 1.3e-14 Hip circumference adjusted for BMI; LIHC cis rs12594515 0.874 rs8032878 chr15:45998015 A/G cg06207120 chr15:45996521 NA 0.31 5.83 0.3 1.27e-8 Waist circumference;Weight; LIHC cis rs9814567 1.000 rs7374158 chr3:134270156 C/T cg15484384 chr3:134203672 ANAPC13;CEP63 -0.4 -5.99 -0.31 5.4e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs6942756 1.000 rs67520056 chr7:128982075 A/G cg02491457 chr7:128862824 NA -0.62 -9.02 -0.44 1.36e-17 White matter hyperintensity burden; LIHC trans rs7618501 1.000 rs7634902 chr3:49762662 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.81 -15.1 -0.63 7.59e-40 Intelligence (multi-trait analysis); LIHC cis rs3818285 0.544 rs9787456 chr10:111711822 A/G cg00817464 chr10:111662876 XPNPEP1 -0.54 -8.19 -0.4 5.35e-15 Superior crus of antihelix expression; LIHC cis rs4423214 1.000 rs4944958 chr11:71168073 A/G cg05163923 chr11:71159392 DHCR7 0.89 13.64 0.59 4.09e-34 Vitamin D levels; LIHC cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 0.28 5.85 0.3 1.16e-8 Autism spectrum disorder or schizophrenia; LIHC cis rs12549902 0.966 rs4317621 chr8:41516581 A/G cg21772509 chr8:41503840 NKX6-3 0.41 6.59 0.34 1.71e-10 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; LIHC cis rs1023500 0.573 rs2269524 chr22:42475703 T/G cg15557168 chr22:42548783 NA 0.44 6.88 0.35 2.8e-11 Schizophrenia; LIHC cis rs36051895 0.632 rs1360063 chr9:5167649 A/G cg02405213 chr9:5042618 JAK2 -0.72 -11.07 -0.51 1.45e-24 Pediatric autoimmune diseases; LIHC cis rs67311347 0.577 rs2371129 chr3:40248393 C/T cg13409248 chr3:40428643 ENTPD3 -0.42 -6.57 -0.33 1.83e-10 Renal cell carcinoma; LIHC cis rs9911578 0.967 rs302843 chr17:56727986 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -8.71 -0.43 1.32e-16 Intelligence (multi-trait analysis); LIHC cis rs6686842 0.562 rs213770 chr1:41614825 T/C cg08462924 chr1:41848221 NA 0.31 5.74 0.3 2.1e-8 Height; LIHC cis rs9898641 1 rs9898641 chr17:57571033 T/C cg13753209 chr17:57696993 CLTC 0.49 6.96 0.35 1.78e-11 Interleukin-1-beta levels; LIHC cis rs7926971 0.631 rs7938009 chr11:12660882 C/T cg25843174 chr11:12811716 TEAD1 0.26 5.91 0.3 8.47e-9 Height; LIHC cis rs3204270 0.714 rs7189 chr17:79668897 C/T cg18367735 chr17:79674897 NA 0.72 8.37 0.41 1.5e-15 Dental caries; LIHC cis rs35110281 0.633 rs2329593 chr21:45121987 T/C cg21573476 chr21:45109991 RRP1B -0.56 -10.69 -0.5 3.28e-23 Mean corpuscular volume; LIHC cis rs7224737 0.957 rs6503687 chr17:40295397 G/A cg00647820 chr17:40259828 DHX58 -0.28 -5.94 -0.31 7.08e-9 Fibrinogen levels; LIHC cis rs3812831 0.695 rs10467349 chr13:114939441 A/G cg08824895 chr13:115047677 UPF3A 0.49 7.12 0.36 6.48e-12 Schizophrenia; LIHC trans rs4889911 1.000 rs4889910 chr17:77839795 C/T cg13131263 chr1:9324393 H6PD 0.41 6.31 0.32 8.66e-10 Electroencephalogram traits; LIHC cis rs12403795 1.000 rs12403795 chr1:150278389 A/G cg18016565 chr1:150552671 MCL1 -0.39 -5.94 -0.31 7.13e-9 Illicit drug use; LIHC cis rs4865169 0.560 rs1277312 chr4:57902945 T/A cg25525207 chr4:57843836 C4orf14;POLR2B -0.38 -5.88 -0.3 1e-8 Breast cancer; LIHC cis rs2979489 0.891 rs3824107 chr8:30353412 A/G cg26383811 chr8:30366931 RBPMS 0.66 10.77 0.5 1.68e-23 Mean corpuscular hemoglobin;Plateletcrit;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Mean corpuscular volume;Myeloid white cell count;Sum neutrophil eosinophil counts; LIHC cis rs801193 1.000 rs62466794 chr7:66191579 G/A cg00343986 chr7:65444356 GUSB 0.41 6.24 0.32 1.28e-9 Aortic root size; LIHC cis rs80282103 0.867 rs74117668 chr10:1076620 C/T cg18964960 chr10:1102726 WDR37 0.67 6.31 0.32 8.41e-10 Glomerular filtration rate (creatinine); LIHC cis rs4665809 0.887 rs4665825 chr2:26333100 A/G cg04944784 chr2:26401820 FAM59B -0.65 -8.3 -0.41 2.39e-15 Gut microbiome composition (summer); LIHC cis rs1165668 0.959 rs1165675 chr12:104320991 G/T cg21863207 chr12:104234989 NT5DC3 -0.4 -6.36 -0.33 6.43e-10 Coronary heart disease (SNP X SNP interaction); LIHC cis rs17376456 0.825 rs13161885 chr5:93071242 A/C cg25358565 chr5:93447407 FAM172A 1.06 9.35 0.45 1.21e-18 Diabetic retinopathy; LIHC cis rs4665809 1.000 rs2053367 chr2:26293413 T/C cg27170947 chr2:26402098 FAM59B -0.64 -7.97 -0.4 2.39e-14 Gut microbiome composition (summer); LIHC cis rs5769765 0.542 rs5769751 chr22:50242733 T/G cg22709217 chr22:50311962 ALG12;CRELD2 0.86 6.13 0.31 2.36e-9 Schizophrenia; LIHC cis rs3806843 0.735 rs809635 chr5:140081791 A/G cg16179182 chr5:140090404 VTRNA1-1 0.37 6.08 0.31 3.24e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs875971 0.545 rs2420456 chr7:65745606 T/G cg05627663 chr7:65219948 SNORA22;CCT6P1 0.37 7.49 0.38 6.01e-13 Aortic root size; LIHC cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg02290350 chr8:58132656 NA 0.49 10.61 0.5 6.4e-23 Developmental language disorder (linguistic errors); LIHC cis rs6840360 0.554 rs61308159 chr4:152728941 G/A cg22705602 chr4:152727874 NA 0.39 8.19 0.4 5.35e-15 Intelligence (multi-trait analysis); LIHC cis rs12477438 0.520 rs11123765 chr2:99768064 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.25 25.02 0.8 2.85e-79 Chronic sinus infection; LIHC cis rs3806843 1.000 rs13184940 chr5:140172918 T/C cg19875535 chr5:140030758 IK 0.36 5.9 0.3 8.8e-9 Depressive symptoms (multi-trait analysis); LIHC trans rs2177312 0.868 rs10024655 chr4:31938944 C/T cg21041181 chr2:42721947 KCNG3 -0.45 -6.27 -0.32 1.11e-9 Very long-chain saturated fatty acid levels (fatty acid 22:0); LIHC cis rs969413 0.535 rs8077394 chr17:79258787 A/G cg08034816 chr17:79219380 SLC38A10 0.4 6.4 0.33 5.13e-10 Frontotemporal dementia; LIHC cis rs9733 0.596 rs17606613 chr1:150683015 C/T cg15448220 chr1:150897856 SETDB1 0.4 6.28 0.32 1.03e-9 Tonsillectomy; LIHC cis rs7726839 0.561 rs4957050 chr5:579066 A/C cg09021430 chr5:549028 NA -0.41 -8.63 -0.42 2.28e-16 Obesity-related traits; LIHC trans rs1814175 0.645 rs847627 chr11:49927177 G/A cg03929089 chr4:120376271 NA -0.84 -15.94 -0.65 3.49e-43 Height; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg20919844 chr3:50388170 TUSC4;CYB561D2 0.45 6.08 0.31 3.21e-9 Lung function (FEV1/FVC); LIHC cis rs9611565 0.765 rs132906 chr22:41799767 G/C cg03806693 chr22:41940476 POLR3H 0.57 7.62 0.38 2.6e-13 Vitiligo; LIHC cis rs2839186 0.721 rs13051200 chr21:47701693 A/T cg09417038 chr21:47716443 C21orf57 -0.5 -7.36 -0.37 1.35e-12 Testicular germ cell tumor; LIHC cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.87 0.39 4.61e-14 Prudent dietary pattern; LIHC cis rs597539 0.617 rs669659 chr11:68635623 G/C cg06028808 chr11:68637592 NA 0.43 5.85 0.3 1.16e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; LIHC cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 7.75 0.39 1.03e-13 Height; LIHC cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.52 -8.32 -0.41 2.07e-15 Schizophrenia; LIHC cis rs2997447 0.761 rs112552200 chr1:26456947 G/A cg19633962 chr1:26362018 EXTL1 -0.67 -6.07 -0.31 3.37e-9 QRS complex (12-leadsum); LIHC trans rs4927850 0.881 rs7624638 chr3:195748729 C/T cg16724585 chr3:197361211 NA -0.47 -6.59 -0.34 1.67e-10 Pancreatic cancer; LIHC cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg10802521 chr3:52805072 NEK4 0.43 7.13 0.36 6.07e-12 Bipolar disorder; LIHC cis rs2749592 0.588 rs2505192 chr10:38395023 G/A cg00409905 chr10:38381863 ZNF37A -0.52 -8.41 -0.41 1.12e-15 Age-related hearing impairment (SNP x SNP interaction); LIHC cis rs2278034 0.578 rs881753 chr3:195606770 C/T cg22809023 chr3:195622598 TNK2 -0.49 -6.87 -0.35 2.97e-11 Bronchopulmonary dysplasia; LIHC cis rs2730245 1.000 rs2657345 chr7:158744169 T/C cg24397884 chr7:158709396 WDR60 -0.42 -6.36 -0.33 6.61e-10 Height; LIHC cis rs7903847 0.620 rs9787454 chr10:99155561 A/T cg06359132 chr10:99160096 RRP12 -0.41 -6.36 -0.33 6.53e-10 Granulocyte percentage of myeloid white cells; LIHC cis rs7546668 1.000 rs4646061 chr1:15829916 G/A cg11706911 chr1:15910989 AGMAT 0.44 6.89 0.35 2.76e-11 Glomerular filtration rate (creatinine); LIHC cis rs1853665 0.580 rs4242282 chr6:150273346 C/G cg16301758 chr6:150275521 NA -0.39 -5.76 -0.3 1.89e-8 Radiation response; LIHC cis rs7954584 0.520 rs1169094 chr12:122465535 A/G cg13699009 chr12:122356056 WDR66 -0.41 -6.82 -0.35 4.12e-11 Mean corpuscular volume; LIHC cis rs1957429 0.901 rs8009996 chr14:65351582 A/G cg23373153 chr14:65346875 NA 0.89 13.14 0.58 3.39e-32 Pediatric areal bone mineral density (radius); LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg15276500 chr20:60879007 ADRM1 0.4 6.21 0.32 1.58e-9 Metabolic traits; LIHC cis rs10751667 0.666 rs6597966 chr11:950750 T/C ch.11.42038R chr11:967971 AP2A2 0.56 10.07 0.48 4.62e-21 Alzheimer's disease (late onset); LIHC cis rs317689 0.690 rs547827 chr12:69669703 G/A cg14784868 chr12:69753453 YEATS4 0.55 7.83 0.39 6.22e-14 Response to diuretic therapy; LIHC cis rs7208859 0.573 rs8070182 chr17:29135594 A/C cg13385521 chr17:29058706 SUZ12P 0.84 8.33 0.41 2e-15 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs2281845 0.965 rs7516023 chr1:201085521 C/T cg24849736 chr1:201084428 NA -0.42 -8.31 -0.41 2.33e-15 Permanent tooth development; LIHC cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg08280861 chr8:58055591 NA 0.5 6.33 0.32 7.67e-10 Developmental language disorder (linguistic errors); LIHC cis rs12586317 0.547 rs28569331 chr14:35473584 T/C cg16230307 chr14:35515116 FAM177A1 0.79 13.27 0.58 1.03e-32 Psoriasis; LIHC cis rs6582630 0.519 rs1607868 chr12:38385512 G/T cg26384229 chr12:38710491 ALG10B 0.59 8.12 0.4 8.71e-15 Drug-induced liver injury (flucloxacillin); LIHC cis rs9443189 0.527 rs775059 chr6:76370130 G/T cg01950844 chr6:76311363 SENP6 0.87 10.84 0.51 9.96e-24 Prostate cancer; LIHC cis rs4589502 1.000 rs58084996 chr15:67123357 T/C cg09911534 chr15:67153556 NA -0.49 -6.09 -0.31 3.08e-9 Lung cancer (smoking interaction); LIHC cis rs7618501 0.521 rs868891 chr3:49949071 A/G cg24110177 chr3:50126178 RBM5 -0.55 -8.81 -0.43 6.59e-17 Intelligence (multi-trait analysis); LIHC cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg11062466 chr8:58055876 NA 0.39 5.77 0.3 1.74e-8 Developmental language disorder (linguistic errors); LIHC cis rs9814567 1.000 rs7374325 chr3:134275601 G/C cg15484384 chr3:134203672 ANAPC13;CEP63 -0.41 -5.91 -0.3 8.46e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC trans rs875971 0.660 rs12698534 chr7:65986845 C/T cg26939375 chr7:64535504 NA 0.43 6.96 0.35 1.72e-11 Aortic root size; LIHC cis rs7089973 0.604 rs11196943 chr10:116598865 T/C cg03647239 chr10:116582469 FAM160B1 0.44 6.58 0.34 1.74e-10 Bipolar disorder or attention deficit hyperactivity disorder; LIHC cis rs9443645 0.869 rs11754419 chr6:79729648 A/G cg05283184 chr6:79620031 NA -0.34 -5.79 -0.3 1.61e-8 Intelligence (multi-trait analysis); LIHC cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg10802521 chr3:52805072 NEK4 -0.46 -7.77 -0.39 9.14e-14 Bipolar disorder; LIHC cis rs2019216 0.835 rs402052 chr17:21908388 G/C cg22648282 chr17:21454238 C17orf51 -0.36 -6.2 -0.32 1.63e-9 Pelvic organ prolapse; LIHC cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg11494091 chr17:61959527 GH2 0.44 8.11 0.4 8.89e-15 Prudent dietary pattern; LIHC cis rs10779751 0.960 rs1883964 chr1:11294942 T/A cg08854313 chr1:11322531 MTOR 0.8 11.24 0.52 3.72e-25 Body mass index; LIHC cis rs7223966 1.000 rs8076717 chr17:61850301 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.6 -7.06 -0.36 9.28e-12 Hip circumference adjusted for BMI;Body mass index; LIHC cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg17554472 chr22:41940697 POLR3H -0.55 -6.26 -0.32 1.12e-9 Vitiligo; LIHC cis rs10504073 0.647 rs62507252 chr8:50028795 C/G cg00325661 chr8:49890786 NA 0.33 7.44 0.37 7.96e-13 Blood metabolite ratios; LIHC cis rs7131987 0.650 rs4331146 chr12:29440083 G/T cg12903224 chr12:29470962 FAR2 -0.41 -6.75 -0.34 6.37e-11 QT interval; LIHC cis rs12188164 0.561 rs2721010 chr5:456915 A/G cg08916839 chr5:415575 AHRR 0.29 6.19 0.32 1.68e-9 Cystic fibrosis severity; LIHC cis rs74544699 1.000 rs77149208 chr4:74768731 C/A cg15398841 chr4:74847761 PF4 0.59 5.77 0.3 1.73e-8 Growth-regulated protein alpha levels; LIHC cis rs1559088 1.000 rs28803235 chr19:33561804 G/A cg27124370 chr19:33622961 WDR88 0.47 6.98 0.35 1.5e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC cis rs4423214 0.650 rs2186777 chr11:71219803 C/A cg05163923 chr11:71159392 DHCR7 0.74 10.74 0.5 2.21e-23 Vitamin D levels; LIHC cis rs1568889 0.877 rs1384903 chr11:28124359 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.46 5.77 0.3 1.75e-8 Bipolar disorder; LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg07677032 chr17:61819896 STRADA 0.43 6.29 0.32 9.74e-10 Prudent dietary pattern; LIHC cis rs7552404 0.961 rs1061337 chr1:76227022 A/G cg03433033 chr1:76189801 ACADM 0.67 9.35 0.45 1.2e-18 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs7772486 0.521 rs9485017 chr6:146023326 C/T cg05347473 chr6:146136440 FBXO30 0.41 6.37 0.33 6.21e-10 Lobe attachment (rater-scored or self-reported); LIHC cis rs11888559 0.573 rs7602826 chr2:203860716 G/A cg24605529 chr2:203879461 NBEAL1 0.72 5.77 0.3 1.74e-8 Height; LIHC cis rs644799 0.544 rs525087 chr11:95632266 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.6 9.26 0.45 2.29e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs13108904 0.936 rs4974540 chr4:1213463 C/T cg00684032 chr4:1343700 KIAA1530 0.38 5.77 0.3 1.82e-8 Obesity-related traits; LIHC cis rs10892173 0.566 rs2298649 chr11:117672225 A/G cg21640587 chr11:117668038 DSCAML1 0.53 6.61 0.34 1.51e-10 Myopia; LIHC cis rs7769051 0.808 rs1467403 chr6:133089952 T/A cg22852734 chr6:133119734 C6orf192 0.88 8.67 0.42 1.78e-16 Type 2 diabetes nephropathy; LIHC cis rs2522056 1.000 rs2522054 chr5:131799526 G/T cg24060327 chr5:131705240 SLC22A5 0.55 7.43 0.37 8.82e-13 Lymphocyte counts;Fibrinogen; LIHC cis rs2153535 0.580 rs1414351 chr6:8476634 T/C cg23788917 chr6:8435910 SLC35B3 0.6 8.55 0.42 4.13e-16 Motion sickness; LIHC cis rs7954584 0.520 rs1169094 chr12:122465535 A/G cg21171335 chr12:122356390 WDR66 -0.42 -6.81 -0.35 4.37e-11 Mean corpuscular volume; LIHC cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg05564831 chr3:52568323 NT5DC2 0.37 6.08 0.31 3.18e-9 Intelligence (multi-trait analysis); LIHC cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.02 22.84 0.78 8.76e-71 Height; LIHC cis rs7208859 0.623 rs11650973 chr17:29214045 G/A cg13385521 chr17:29058706 SUZ12P 0.82 8.07 0.4 1.24e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs4903214 0.848 rs62006811 chr14:74717699 C/A cg11132536 chr14:74711944 VSX2 -0.24 -5.98 -0.31 5.48e-9 Inflammatory bowel disease; LIHC cis rs6912958 0.781 rs4707379 chr6:88310623 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.44 -7.72 -0.39 1.33e-13 Monocyte percentage of white cells; LIHC cis rs9300255 0.566 rs10744150 chr12:123721614 A/C cg00376283 chr12:123451042 ABCB9 0.69 10.45 0.49 2.36e-22 Neutrophil percentage of white cells; LIHC cis rs4555082 0.874 rs1008628 chr14:105722726 T/C cg13114125 chr14:105738426 BRF1 -0.69 -9.08 -0.44 8.83e-18 Mean platelet volume;Platelet distribution width; LIHC cis rs11098499 0.955 rs1511015 chr4:120170473 A/C cg09307838 chr4:120376055 NA 0.74 11.0 0.51 2.76e-24 Corneal astigmatism; LIHC cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg08219700 chr8:58056026 NA 0.52 7.13 0.36 5.84e-12 Developmental language disorder (linguistic errors); LIHC cis rs922107 0.738 rs12119009 chr1:90023756 C/G cg15422784 chr1:90023713 LRRC8B -0.49 -8.05 -0.4 1.4e-14 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); LIHC cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.72 0.34 7.4e-11 Diabetic kidney disease; LIHC cis rs854765 0.647 rs854767 chr17:18018263 A/C cg04398451 chr17:18023971 MYO15A 0.68 12.24 0.55 8.16e-29 Total body bone mineral density; LIHC cis rs10276381 0.786 rs28430601 chr7:28238811 A/G cg23620719 chr7:28220237 JAZF1 0.63 7.37 0.37 1.31e-12 Crohn's disease; LIHC cis rs477895 0.713 rs67546972 chr11:63962162 G/A cg04317338 chr11:64019027 PLCB3 0.84 10.13 0.48 2.89e-21 Mean platelet volume; LIHC cis rs400736 0.535 rs4418631 chr1:8174197 A/G cg25007680 chr1:8021821 PARK7 0.53 8.09 0.4 1.05e-14 Response to antidepressants and depression; LIHC cis rs72653721 0.793 rs59578052 chr6:10966620 C/T cg13562911 chr6:11044106 ELOVL2 0.48 6.83 0.35 3.96e-11 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); LIHC cis rs2153535 0.580 rs6597325 chr6:8461053 A/C cg23788917 chr6:8435910 SLC35B3 0.61 8.65 0.42 1.99e-16 Motion sickness; LIHC cis rs6461049 0.646 rs3778970 chr7:2143208 C/A cg20295408 chr7:1910781 MAD1L1 -0.41 -6.07 -0.31 3.41e-9 Schizophrenia; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg14710165 chr8:126104387 KIAA0196;NSMCE2 0.46 6.45 0.33 3.76e-10 Pancreatic cancer; LIHC cis rs757081 0.667 rs3950680 chr11:17138666 G/A cg15432903 chr11:17409602 KCNJ11 -0.42 -5.91 -0.3 8.46e-9 Systolic blood pressure; LIHC cis rs208520 1.000 rs12199876 chr6:66989469 A/G cg07460842 chr6:66804631 NA 0.67 7.28 0.37 2.33e-12 Exhaled nitric oxide output; LIHC cis rs7980687 0.657 rs10744151 chr12:123723735 G/C cg05973401 chr12:123451056 ABCB9 0.43 5.97 0.31 5.84e-9 Height;Educational attainment;Head circumference (infant); LIHC cis rs2228479 0.702 rs62053702 chr16:89860688 G/T cg19635926 chr16:89946313 TCF25 0.55 6.84 0.35 3.57e-11 Skin colour saturation; LIHC cis rs420259 0.727 rs35635 chr16:23693770 G/T cg05131483 chr16:23706242 ERN2 -0.33 -5.87 -0.3 1.06e-8 Bipolar disorder; LIHC cis rs1559088 0.895 rs7246562 chr19:33546088 T/G cg27124370 chr19:33622961 WDR88 0.46 7.03 0.36 1.16e-11 Bone ultrasound measurement (broadband ultrasound attenuation); LIHC trans rs75804782 0.641 rs3769123 chr2:239349328 C/G cg01134436 chr17:81009848 B3GNTL1 0.8 6.95 0.35 1.89e-11 Morning vs. evening chronotype;Chronotype; LIHC trans rs7618501 0.602 rs2624816 chr3:50117312 T/G cg21659725 chr3:3221576 CRBN -0.66 -10.5 -0.49 1.58e-22 Intelligence (multi-trait analysis); LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg26016210 chr1:156426331 NA 0.44 6.09 0.31 3.12e-9 Lung function (FEV1/FVC); LIHC cis rs35160687 0.545 rs1863050 chr2:86558376 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 0.37 5.89 0.3 9.09e-9 Night sleep phenotypes; LIHC cis rs4555082 0.718 rs75139030 chr14:105710853 A/AG cg06808227 chr14:105710500 BRF1 -0.49 -6.1 -0.31 2.89e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs2439831 0.702 rs28699233 chr15:44122866 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.55 6.55 0.33 2.07e-10 Lung cancer in ever smokers; LIHC cis rs929354 1.000 rs1182385 chr7:157040583 C/T cg17757837 chr7:157058334 UBE3C -0.8 -14.58 -0.62 8.81e-38 Body mass index; LIHC cis rs17826219 0.568 rs7213925 chr17:29121634 A/G cg14067834 chr17:29058358 SUZ12P 0.71 7.05 0.36 1e-11 Body mass index; LIHC trans rs11098499 0.863 rs36040693 chr4:120477616 A/G cg25214090 chr10:38739885 LOC399744 0.59 9.47 0.46 4.64e-19 Corneal astigmatism; LIHC cis rs10924970 0.601 rs12402448 chr1:235448095 A/T cg26050004 chr1:235667680 B3GALNT2 0.4 5.77 0.3 1.8e-8 Asthma; LIHC cis rs67981189 0.593 rs2526873 chr14:71381671 C/T cg15816911 chr14:71606274 NA -0.43 -6.77 -0.34 5.72e-11 Schizophrenia; LIHC cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg23221052 chr5:179740743 GFPT2 -0.45 -6.25 -0.32 1.25e-9 Height; LIHC cis rs1348850 0.526 rs7588049 chr2:178390778 C/T cg27490568 chr2:178487706 NA -0.98 -11.05 -0.51 1.78e-24 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); LIHC cis rs7589728 0.688 rs76734941 chr2:88530454 T/C cg07952391 chr2:88470173 THNSL2 0.68 5.74 0.3 2.13e-8 Plasma clusterin levels; LIHC cis rs907683 0.635 rs11691617 chr2:220295167 C/T cg15015639 chr2:220282977 DES 0.38 8.98 0.44 1.79e-17 Resting heart rate; LIHC cis rs11958404 0.932 rs72818108 chr5:157437883 A/T cg05962755 chr5:157440814 NA 1.05 11.93 0.54 1.12e-27 IgG glycosylation; LIHC cis rs3849570 0.695 rs6804587 chr3:81873423 T/C cg07356753 chr3:81810745 GBE1 -0.54 -8.65 -0.42 2.03e-16 Waist circumference;Body mass index; LIHC trans rs62103177 0.810 rs62103188 chr18:77627661 G/A cg05926928 chr17:57297772 GDPD1 1.11 11.42 0.53 8.64e-26 Opioid sensitivity; LIHC cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg19729930 chr2:74357872 NA 0.81 17.73 0.69 2.49e-50 Gestational age at birth (maternal effect); LIHC trans rs3764796 0.748 rs2904699 chr8:17090798 A/G cg14047339 chr6:45345544 RUNX2;SUPT3H 0.41 6.16 0.32 2.09e-9 Calcium levels; LIHC cis rs13161895 0.818 rs78282770 chr5:179483686 T/A cg06664874 chr5:179499304 RNF130 0.65 7.57 0.38 3.43e-13 LDL cholesterol; LIHC cis rs2066819 1.000 rs17118439 chr12:56667604 C/T cg26714650 chr12:56694279 CS 1.32 13.36 0.59 4.92e-33 Psoriasis vulgaris; LIHC cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.73 10.67 0.5 3.93e-23 Lymphocyte counts; LIHC cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg09417038 chr21:47716443 C21orf57 -0.65 -9.46 -0.46 5.26e-19 Testicular germ cell tumor; LIHC cis rs8177179 0.967 rs4994581 chr3:133437563 T/C cg18769074 chr3:133464867 TF 0.26 5.78 0.3 1.64e-8 Iron status biomarkers (transferrin levels); LIHC cis rs7100689 0.577 rs4934038 chr10:82057334 C/A cg00277334 chr10:82204260 NA -0.56 -6.81 -0.35 4.51e-11 Post bronchodilator FEV1; LIHC cis rs11098699 0.821 rs13110588 chr4:124220676 A/G cg09941581 chr4:124220074 SPATA5 -0.33 -6.54 -0.33 2.27e-10 Mosquito bite size; LIHC cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg02244288 chr16:89573955 SPG7 -0.31 -5.95 -0.31 6.56e-9 Multiple myeloma (IgH translocation); LIHC cis rs9788682 0.948 rs59133824 chr15:78833450 C/A cg06917634 chr15:78832804 PSMA4 -0.55 -7.77 -0.39 9.12e-14 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; LIHC cis rs10779751 1.000 rs2300092 chr1:11266464 T/C cg08854313 chr1:11322531 MTOR 0.86 15.56 0.64 1.14e-41 Body mass index; LIHC cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg10360323 chr17:41437877 NA 0.39 5.73 0.3 2.23e-8 Menopause (age at onset); LIHC cis rs7312933 0.558 rs2178753 chr12:42732804 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.54 -8.03 -0.4 1.58e-14 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); LIHC trans rs916888 0.773 rs199448 chr17:44809001 A/G cg26692224 chr17:62915920 LRRC37A3 -0.74 -7.13 -0.36 5.91e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; LIHC cis rs7107174 1.000 rs10793309 chr11:78093799 G/A cg02023728 chr11:77925099 USP35 0.42 7.78 0.39 8.62e-14 Testicular germ cell tumor; LIHC cis rs9399135 0.684 rs1135205 chr6:135281795 C/T cg22676075 chr6:135203613 NA 0.4 6.6 0.34 1.6e-10 Red blood cell count; LIHC cis rs17776563 0.887 rs8030854 chr15:89133549 C/T cg05013243 chr15:89149849 MIR1179 0.41 6.74 0.34 6.77e-11 Thyroid hormone levels; LIHC cis rs9733 0.650 rs1971378 chr1:150597261 C/T cg13175981 chr1:150552382 MCL1 0.6 9.27 0.45 2.15e-18 Tonsillectomy; LIHC trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg00822255 chr10:73579668 PSAP 0.41 6.03 0.31 4.16e-9 Alopecia areata; LIHC cis rs3540 0.597 rs4620932 chr15:91036569 G/A cg22089800 chr15:90895588 ZNF774 0.6 8.17 0.4 6.1e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; LIHC cis rs9790314 1.000 rs7653361 chr3:160992291 C/T cg04691961 chr3:161091175 C3orf57 -0.4 -6.28 -0.32 1.01e-9 Morning vs. evening chronotype; LIHC cis rs1865760 0.929 rs1816546 chr6:25938252 C/T cg15691649 chr6:25882328 NA -0.39 -6.15 -0.32 2.18e-9 Height; LIHC cis rs16866061 1.000 rs11681451 chr2:225334104 T/C cg12698349 chr2:225449008 CUL3 0.73 12.56 0.56 5.31e-30 Acute graft versus host disease in bone marrow transplantation (recipient effect); LIHC cis rs9549328 0.878 rs9577407 chr13:113639671 G/A cg08528486 chr13:113648767 MCF2L -0.38 -6.24 -0.32 1.32e-9 Systolic blood pressure; LIHC cis rs1801251 1.000 rs11679079 chr2:233612656 C/T cg25237894 chr2:233734115 C2orf82 0.58 11.15 0.52 7.7e-25 Coronary artery disease; LIHC cis rs7221595 0.778 rs9916457 chr17:3929659 A/C cg09597638 chr17:3907349 NA 0.47 6.31 0.32 8.73e-10 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; LIHC cis rs11864453 0.612 rs12708925 chr16:72122706 A/T cg01557791 chr16:72042693 DHODH -0.43 -7.13 -0.36 6.16e-12 Fibrinogen levels; LIHC cis rs6088590 0.735 rs2273684 chr20:33529766 G/T cg07148914 chr20:33460835 GGT7 -0.48 -6.55 -0.33 2.08e-10 Coronary artery disease; LIHC cis rs7605378 0.567 rs717915 chr2:200714766 C/T cg12253985 chr2:200820533 C2orf60;C2orf47 0.55 7.0 0.35 1.34e-11 Osteoporosis; LIHC cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg18306943 chr3:40428807 ENTPD3 -0.35 -5.98 -0.31 5.48e-9 Renal cell carcinoma; LIHC cis rs7412746 0.611 rs6660084 chr1:150748803 T/C cg18016565 chr1:150552671 MCL1 0.54 10.13 0.48 2.88e-21 Melanoma; LIHC trans rs11760633 0.607 rs11765833 chr7:1830116 A/C cg00395210 chr12:48592465 NA 0.34 6.08 0.31 3.19e-9 Coronary artery disease; LIHC cis rs7917772 0.636 rs2863718 chr10:104519631 G/C cg22532475 chr10:104410764 TRIM8 0.37 6.39 0.33 5.3e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; LIHC cis rs17818399 0.633 rs2242033 chr2:46842410 A/G cg02822958 chr2:46747628 ATP6V1E2 0.41 6.56 0.33 2.04e-10 Height; LIHC cis rs35306767 0.903 rs13377166 chr10:886259 G/A cg26597838 chr10:835615 NA 1.21 14.35 0.61 7.24e-37 Eosinophil percentage of granulocytes; LIHC cis rs7772486 0.686 rs9376961 chr6:146048737 C/T cg13319975 chr6:146136371 FBXO30 -0.37 -6.05 -0.31 3.85e-9 Lobe attachment (rater-scored or self-reported); LIHC cis rs898097 0.812 rs56274787 chr17:80862682 C/T cg15369054 chr17:80825471 TBCD 0.43 6.05 0.31 3.73e-9 Breast cancer; LIHC trans rs950169 0.579 rs12913054 chr15:84664456 A/G cg00571809 chr1:3397113 ARHGEF16 0.39 6.39 0.33 5.55e-10 Schizophrenia; LIHC cis rs17253792 0.822 rs76555508 chr14:56071868 A/G cg01858014 chr14:56050164 KTN1 -0.79 -8.63 -0.42 2.3e-16 Putamen volume; LIHC cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg04944784 chr2:26401820 FAM59B 0.72 9.21 0.45 3.36e-18 Gut microbiome composition (summer); LIHC cis rs7027203 0.663 rs4428726 chr9:96623559 T/G cg14598338 chr9:96623480 NA -0.35 -7.17 -0.36 4.56e-12 DNA methylation (variation); LIHC trans rs2243480 1.000 rs34637256 chr7:65360131 G/A cg10756647 chr7:56101905 PSPH 1.09 13.38 0.59 4.07e-33 Diabetic kidney disease; LIHC trans rs7615952 0.932 rs7629977 chr3:125649573 T/G cg07211511 chr3:129823064 LOC729375 -0.85 -10.68 -0.5 3.62e-23 Blood pressure (smoking interaction); LIHC cis rs3743266 0.507 rs62005026 chr15:60698454 A/G cg22293140 chr15:60689852 ANXA2 -0.62 -6.15 -0.32 2.2e-9 Menarche (age at onset); LIHC cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg12463550 chr7:65579703 CRCP 0.69 7.11 0.36 6.63e-12 Diabetic kidney disease; LIHC cis rs12079745 0.793 rs12067351 chr1:169279758 T/A cg09363564 chr1:169337483 NME7;BLZF1 -0.77 -6.94 -0.35 1.94e-11 QT interval; LIHC cis rs6500602 0.727 rs8051389 chr16:4570570 C/T cg13763550 chr16:4524223 NMRAL1;HMOX2 0.43 6.07 0.31 3.42e-9 Schizophrenia; LIHC cis rs9902453 0.933 rs8080343 chr17:28456758 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 9.2 0.45 3.51e-18 Coffee consumption (cups per day); LIHC cis rs1799949 1.000 rs35070007 chr17:41316747 C/G cg05368731 chr17:41323189 NBR1 -0.68 -11.43 -0.53 7.6e-26 Menopause (age at onset); LIHC cis rs9583531 0.600 rs7984468 chr13:111362093 C/A cg24331049 chr13:111365604 ING1 0.78 13.14 0.58 3.32e-32 Coronary artery disease; LIHC trans rs4566357 0.615 rs1800517 chr2:227915832 G/A cg16088116 chr21:44841560 SIK1 -0.42 -6.49 -0.33 2.93e-10 Coronary artery disease; LIHC cis rs1534166 1.000 rs1534166 chr3:133537067 C/T cg12373951 chr3:133503437 NA 0.46 6.24 0.32 1.33e-9 Alcohol consumption (transferrin glycosylation); LIHC cis rs797680 0.822 rs1057257 chr1:93621483 A/G cg15093775 chr1:93646470 TMED5;CCDC18 -0.34 -6.01 -0.31 4.67e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts; LIHC cis rs11711311 1.000 rs2305545 chr3:113499733 A/G cg15478005 chr3:113465772 ATP6V1A;NAA50 0.47 9.06 0.44 9.93e-18 IgG glycosylation; LIHC cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 6.11 0.31 2.77e-9 Menopause (age at onset); LIHC cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg23172400 chr8:95962367 TP53INP1 -0.43 -10.16 -0.48 2.28e-21 Type 2 diabetes; LIHC cis rs1865721 0.917 rs62089506 chr18:73178913 A/G cg26385618 chr18:73139727 C18orf62 -0.3 -7.67 -0.38 1.77e-13 Intelligence; LIHC cis rs6701037 0.681 rs1894709 chr1:175132371 G/T cg17845761 chr1:175162550 KIAA0040 -0.41 -6.78 -0.34 5.15e-11 Alcohol dependence; LIHC cis rs6748734 0.817 rs10182575 chr2:241806690 C/T cg20140201 chr2:241835670 C2orf54 -0.5 -7.64 -0.38 2.23e-13 Urinary metabolites; LIHC trans rs11098499 0.569 rs55845118 chr4:120290913 T/C cg25214090 chr10:38739885 LOC399744 0.48 7.73 0.39 1.23e-13 Corneal astigmatism; LIHC cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.49 7.78 0.39 8.43e-14 Prudent dietary pattern; LIHC cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg20887711 chr4:1340912 KIAA1530 -0.52 -8.11 -0.4 8.87e-15 Obesity-related traits; LIHC cis rs2303759 0.918 rs2288480 chr19:49867016 C/G cg24324837 chr19:49891574 CCDC155 0.39 6.16 0.32 2.05e-9 Multiple sclerosis; LIHC cis rs1003719 0.680 rs1034357 chr21:38571482 G/C cg10648535 chr21:38446584 PIGP;TTC3 -0.69 -10.43 -0.49 2.6e-22 Eye color traits; LIHC cis rs10927875 0.632 rs10927863 chr1:16165247 C/A cg21385522 chr1:16154831 NA -1.04 -17.5 -0.69 2.1e-49 Dilated cardiomyopathy; LIHC cis rs6540556 0.723 rs12116437 chr1:209897027 G/A cg05527609 chr1:210001259 C1orf107 -0.56 -7.61 -0.38 2.74e-13 Red blood cell count; LIHC cis rs950169 0.845 rs4502182 chr15:84923520 A/G cg17507749 chr15:85114479 UBE2QP1 0.74 8.91 0.43 3.12e-17 Schizophrenia; LIHC cis rs62380364 0.602 rs588282 chr5:88032651 G/T cg22951263 chr5:87985283 NA -0.39 -6.81 -0.35 4.53e-11 Intelligence (multi-trait analysis); LIHC cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg13271783 chr10:134563150 INPP5A -0.61 -7.26 -0.37 2.56e-12 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs1707322 0.964 rs785508 chr1:46527159 G/A cg06784218 chr1:46089804 CCDC17 -0.38 -6.96 -0.35 1.71e-11 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs6088590 1.000 rs6120750 chr20:33465289 A/C cg06115741 chr20:33292138 TP53INP2 0.57 7.84 0.39 5.75e-14 Coronary artery disease; LIHC cis rs2204008 0.749 rs4579984 chr12:38166266 A/G cg26384229 chr12:38710491 ALG10B 0.82 10.55 0.5 1.02e-22 Bladder cancer; LIHC cis rs2073300 1.000 rs6048810 chr20:23446429 G/A cg12062639 chr20:23401060 NAPB 0.83 9.73 0.47 6.59e-20 Peripheral arterial disease (traffic-related air pollution interaction); LIHC trans rs17685 0.753 rs10952840 chr7:75772878 C/T cg19862616 chr7:65841803 NCRNA00174 0.93 19.24 0.72 1.99e-56 Coffee consumption;Coffee consumption (cups per day); LIHC cis rs35110281 0.805 rs162402 chr21:44963418 G/C cg04455712 chr21:45112962 RRP1B 0.45 7.52 0.38 5.01e-13 Mean corpuscular volume; LIHC cis rs2732480 0.500 rs7315820 chr12:48598938 C/T cg21466736 chr12:48725269 NA -0.71 -11.02 -0.51 2.22e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.03 9.42 0.45 6.79e-19 Platelet count; LIHC cis rs9914988 0.943 rs11652272 chr17:27167973 C/G cg20469991 chr17:27169893 C17orf63 -0.61 -7.01 -0.35 1.27e-11 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; LIHC cis rs7193541 0.684 rs8062783 chr16:74691264 C/T cg01733217 chr16:74700730 RFWD3 -0.88 -21.14 -0.75 5.01e-64 Multiple myeloma; LIHC trans rs983392 0.709 rs56273223 chr11:59984676 A/C cg17275991 chr19:58003312 ZNF419 0.44 6.25 0.32 1.2e-9 Alzheimer's disease (late onset); LIHC cis rs9733 0.596 rs12403255 chr1:150660412 C/T cg15448220 chr1:150897856 SETDB1 0.41 6.47 0.33 3.3e-10 Tonsillectomy; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg01911186 chr12:12765398 CREBL2 0.52 7.58 0.38 3.35e-13 Pancreatic cancer; LIHC cis rs56235845 0.694 rs11949401 chr5:176765989 A/G cg06060754 chr5:176797920 RGS14 0.46 6.6 0.34 1.58e-10 Hemoglobin concentration;Hematocrit; LIHC cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg09904177 chr6:26538194 HMGN4 0.57 11.34 0.52 1.58e-25 Intelligence (multi-trait analysis); LIHC cis rs2806561 0.823 rs658508 chr1:23480362 T/C cg19743168 chr1:23544995 NA 0.39 7.19 0.36 4.03e-12 Height; LIHC cis rs17152411 0.652 rs10794190 chr10:126603231 G/A cg07906193 chr10:126599966 NA -0.3 -5.92 -0.3 7.9e-9 Height; LIHC cis rs2932538 0.922 rs112363416 chr1:113107543 T/C cg22162597 chr1:113214053 CAPZA1 0.71 9.53 0.46 2.99e-19 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; LIHC cis rs2334880 0.638 rs35166226 chr16:71443219 T/C cg06353428 chr16:71660113 MARVELD3 -0.93 -8.04 -0.4 1.44e-14 Malaria; LIHC cis rs5758511 0.680 rs5758652 chr22:42612408 T/C cg00645731 chr22:42541494 CYP2D7P1 0.53 8.56 0.42 3.8e-16 Birth weight; LIHC cis rs8017423 0.967 rs7147809 chr14:90715025 A/G cg04374321 chr14:90722782 PSMC1 0.74 14.52 0.62 1.51e-37 Mortality in heart failure; LIHC cis rs477895 0.713 rs35095324 chr11:63948412 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 9.63 0.46 1.44e-19 Mean platelet volume; LIHC cis rs2637266 1.000 rs4979784 chr10:78355476 T/A cg18941641 chr10:78392320 NA 0.29 6.17 0.32 1.88e-9 Pulmonary function; LIHC cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg20295408 chr7:1910781 MAD1L1 -0.51 -7.3 -0.37 1.97e-12 Bipolar disorder and schizophrenia; LIHC cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg07167872 chr1:205819463 PM20D1 0.67 9.37 0.45 1.04e-18 Menarche (age at onset); LIHC cis rs7927771 0.832 rs7105851 chr11:47383275 T/C cg20135002 chr11:47629003 NA 0.51 8.67 0.42 1.8e-16 Subjective well-being; LIHC trans rs35110281 0.548 rs7276316 chr21:45029333 A/T cg18724061 chr6:27861294 HIST1H2AM;HIST1H2BO 0.46 6.27 0.32 1.11e-9 Mean corpuscular volume; LIHC cis rs6754311 0.731 rs7579771 chr2:136580260 T/A cg07169764 chr2:136633963 MCM6 0.67 10.11 0.48 3.43e-21 Mosquito bite size; LIHC cis rs4808199 0.739 rs2240117 chr19:19418916 C/T cg21559469 chr19:19431446 KIAA0892;SF4 0.5 6.0 0.31 4.97e-9 Nonalcoholic fatty liver disease; LIHC cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg03517284 chr6:25882590 NA -0.63 -7.8 -0.39 7.41e-14 Intelligence (multi-trait analysis); LIHC cis rs7613875 0.620 rs13079006 chr3:49996924 G/T cg21467203 chr3:49911342 NA -0.53 -9.74 -0.47 6.1e-20 Body mass index; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg16583193 chr19:3652060 PIP5K1C 0.43 6.34 0.32 7.1e-10 Longevity; LIHC cis rs1728785 0.892 rs4783562 chr16:68562963 A/G cg02972257 chr16:68554789 NA -0.55 -6.26 -0.32 1.19e-9 Ulcerative colitis; LIHC cis rs10870270 1.000 rs6560694 chr10:133773448 G/A cg26149184 chr10:133730230 NA 0.47 7.39 0.37 1.11e-12 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; LIHC cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg20295408 chr7:1910781 MAD1L1 -0.42 -6.21 -0.32 1.53e-9 Bipolar disorder and schizophrenia; LIHC cis rs929354 0.772 rs2051876 chr7:157009037 A/G cg05182265 chr7:156933206 UBE3C 0.33 6.23 0.32 1.34e-9 Body mass index; LIHC cis rs4953318 0.619 rs35744969 chr2:46353140 C/A cg12428440 chr2:46370979 PRKCE 0.44 5.97 0.31 6.07e-9 Red blood cell count;Hematocrit;Red blood cell traits; LIHC cis rs17102423 0.594 rs942626 chr14:65550082 C/T cg16583315 chr14:65563665 MAX -0.39 -7.95 -0.39 2.73e-14 Obesity-related traits; LIHC cis rs2797160 0.547 rs4144549 chr6:125945251 C/G cg05901451 chr6:126070800 HEY2 0.45 8.03 0.4 1.57e-14 Endometrial cancer; LIHC cis rs8114671 0.562 rs6088653 chr20:33520321 T/C cg07148914 chr20:33460835 GGT7 0.65 9.87 0.47 2.25e-20 Height; LIHC cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg20607798 chr8:58055168 NA 0.49 6.22 0.32 1.48e-9 Developmental language disorder (linguistic errors); LIHC cis rs644799 1.000 rs11021319 chr11:95523123 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.93 17.31 0.68 1.22e-48 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); LIHC cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.01 24.95 0.8 5.46e-79 Prudent dietary pattern; LIHC cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 8.0 0.4 1.96e-14 Height; LIHC cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 9.76 0.47 5.3e-20 Platelet count; LIHC cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg24209194 chr3:40518798 ZNF619 0.63 9.53 0.46 3.05e-19 Renal cell carcinoma; LIHC cis rs703842 0.616 rs10877024 chr12:58226709 C/T cg18357645 chr12:58087776 OS9 -0.42 -6.03 -0.31 4.37e-9 Multiple sclerosis; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg24218925 chr19:2578938 GNG7 0.43 6.47 0.33 3.33e-10 Lung function (FEV1/FVC); LIHC cis rs4908768 0.501 rs12030885 chr1:8781396 A/G cg20416874 chr1:8611966 RERE -0.6 -11.02 -0.51 2.33e-24 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg03517284 chr6:25882590 NA 0.56 7.69 0.38 1.5700000000000001e-13 Blood metabolite levels; LIHC cis rs870825 1.000 rs870821 chr4:185587377 T/C cg04058563 chr4:185651563 MLF1IP 0.72 6.11 0.31 2.74e-9 Blood protein levels; LIHC cis rs16944613 0.541 rs7183319 chr15:91095032 A/T cg26821196 chr15:91095069 CRTC3 0.47 8.15 0.4 6.75e-15 Colorectal cancer; LIHC cis rs5769707 0.681 rs2319346 chr22:50029640 A/G cg01652190 chr22:50026171 C22orf34 -0.34 -7.59 -0.38 3.17e-13 Monocyte count;Monocyte percentage of white cells; LIHC cis rs2153535 0.601 rs6906170 chr6:8543128 T/A cg21535247 chr6:8435926 SLC35B3 0.64 8.29 0.41 2.58e-15 Motion sickness; LIHC trans rs8073060 0.544 rs8072676 chr17:33999517 C/T cg19694781 chr19:47549865 TMEM160 -1.19 -12.09 -0.55 2.88e-28 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; LIHC cis rs2204008 0.580 rs36118148 chr12:38411812 G/A cg26384229 chr12:38710491 ALG10B -0.47 -6.12 -0.31 2.57e-9 Bladder cancer; LIHC cis rs240764 0.817 rs239232 chr6:101103038 G/A cg09795085 chr6:101329169 ASCC3 0.51 7.1 0.36 7.04e-12 Neuroticism; LIHC cis rs875971 0.543 rs801191 chr7:66032955 G/A cg11764359 chr7:65958608 NA -0.62 -9.49 -0.46 4.18e-19 Aortic root size; LIHC cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg24250549 chr1:154909240 PMVK 0.68 10.81 0.5 1.26e-23 Prostate cancer; LIHC cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg06481639 chr22:41940642 POLR3H 0.61 5.87 0.3 1.02e-8 Vitiligo; LIHC cis rs9303280 0.837 rs907092 chr17:37922259 A/G cg11212589 chr17:38028394 ZPBP2 -0.3 -5.93 -0.31 7.62e-9 Self-reported allergy; LIHC cis rs709400 0.859 rs942863 chr14:104021268 C/T cg26031613 chr14:104095156 KLC1 1.14 14.58 0.62 8.9e-38 Body mass index; LIHC cis rs4908768 0.906 rs56163601 chr1:8751897 G/A cg20416874 chr1:8611966 RERE 0.53 8.02 0.4 1.71e-14 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); LIHC cis rs3790844 0.667 rs3790843 chr1:200010824 A/G cg07208853 chr1:200005219 NR5A2 -0.39 -8.63 -0.42 2.34e-16 Pancreatic cancer; LIHC cis rs2439831 0.850 rs7168158 chr15:44050376 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.52 6.43 0.33 4.32e-10 Lung cancer in ever smokers; LIHC cis rs4555082 0.681 rs28588570 chr14:105709606 A/T cg10792982 chr14:105748885 BRF1 0.43 5.94 0.31 6.83e-9 Mean platelet volume;Platelet distribution width; LIHC cis rs4911259 0.552 rs62208880 chr20:31463284 T/C cg13636640 chr20:31349939 DNMT3B -0.6 -10.65 -0.5 4.57e-23 Inflammatory bowel disease; LIHC cis rs992157 0.731 rs1399132 chr2:219159770 G/A cg20019365 chr2:219134978 PNKD;AAMP 0.8 12.91 0.57 2.53e-31 Colorectal cancer; LIHC cis rs9640161 0.750 rs3735173 chr7:150020526 C/T cg12556325 chr7:150026731 C7orf29;LRRC61 -0.47 -8.27 -0.41 3.01e-15 Blood protein levels;Circulating chemerin levels; LIHC cis rs6450176 0.625 rs11747281 chr5:53289047 G/A ch.5.1024479R chr5:53302184 ARL15 -0.89 -16.49 -0.67 2.23e-45 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs6860806 0.507 rs169256 chr5:131688533 A/G cg24060327 chr5:131705240 SLC22A5 -0.71 -8.86 -0.43 4.3e-17 Breast cancer; LIHC cis rs79839061 0.610 rs11732965 chr4:869359 C/A cg07828340 chr4:882639 GAK 0.83 7.02 0.36 1.18e-11 Intelligence (multi-trait analysis); LIHC cis rs5769765 0.773 rs9616391 chr22:50314573 C/T cg09182678 chr22:50328711 NA -0.44 -6.31 -0.32 8.51e-10 Schizophrenia; LIHC trans rs8117834 0.574 rs7265353 chr20:8085660 G/C cg00593689 chr4:53575888 NA 0.38 6.44 0.33 3.98e-10 Chronic kidney disease; LIHC cis rs875971 0.825 rs7384021 chr7:66077904 A/G cg11764359 chr7:65958608 NA -0.78 -13.64 -0.59 4.13e-34 Aortic root size; LIHC cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg07424592 chr7:64974309 NA 0.8 9.32 0.45 1.45e-18 Diabetic kidney disease; LIHC cis rs4718428 0.705 rs12698547 chr7:66278258 T/C cg18252515 chr7:66147081 NA -0.69 -9.41 -0.45 7.36e-19 Corneal structure; LIHC cis rs4934494 0.727 rs12783582 chr10:91494967 T/C cg19698084 chr10:91461284 KIF20B -0.48 -6.4 -0.33 5.06e-10 Red blood cell count; LIHC cis rs6088590 1.000 rs28542147 chr20:33376323 G/A cg06115741 chr20:33292138 TP53INP2 0.59 8.05 0.4 1.41e-14 Coronary artery disease; LIHC cis rs798554 0.660 rs2527692 chr7:2856533 G/A cg13628971 chr7:2884303 GNA12 0.43 6.68 0.34 9.42e-11 Height; LIHC trans rs1728785 1.000 rs1728780 chr16:68567642 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.49 6.11 0.31 2.65e-9 Ulcerative colitis; LIHC cis rs10504229 1.000 rs59843034 chr8:58195756 T/G cg20607798 chr8:58055168 NA 0.59 6.85 0.35 3.44e-11 Developmental language disorder (linguistic errors); LIHC trans rs2727020 0.523 rs7948958 chr11:49506749 G/A cg03929089 chr4:120376271 NA 0.69 10.09 0.48 3.97e-21 Coronary artery disease; LIHC trans rs2727020 0.729 rs34647977 chr11:49195543 G/A cg15704280 chr7:45808275 SEPT13 -0.89 -16.49 -0.67 2.38e-45 Coronary artery disease; LIHC cis rs600806 0.850 rs10745355 chr1:109951711 T/C cg16275483 chr1:110013120 SYPL2 -0.47 -5.77 -0.3 1.78e-8 Intelligence (multi-trait analysis); LIHC cis rs7572733 0.534 rs700681 chr2:198711502 C/A cg03934865 chr2:198174659 NA 0.46 6.57 0.33 1.83e-10 Dermatomyositis; LIHC cis rs921968 0.643 rs522377 chr2:219437476 T/C cg02985541 chr2:219472218 PLCD4 0.44 8.29 0.41 2.53e-15 Mean corpuscular hemoglobin concentration; LIHC cis rs1816752 0.875 rs59686377 chr13:25050007 C/T cg22771759 chr13:24902376 NA 0.31 6.52 0.33 2.49e-10 Obesity-related traits; LIHC cis rs7264396 0.563 rs2425071 chr20:34292961 A/C cg04508476 chr20:34239394 CPNE1;RBM12 0.56 7.88 0.39 4.3e-14 Total cholesterol levels; LIHC cis rs6701037 0.681 rs1894709 chr1:175132371 G/T cg00321850 chr1:175162397 KIAA0040 -0.44 -6.95 -0.35 1.9e-11 Alcohol dependence; LIHC cis rs875971 0.862 rs6460282 chr7:65691246 T/C cg11764359 chr7:65958608 NA -0.76 -12.43 -0.56 1.63e-29 Aortic root size; LIHC cis rs3790844 0.876 rs61486545 chr1:200008337 G/A cg07208853 chr1:200005219 NR5A2 0.4 8.61 0.42 2.65e-16 Pancreatic cancer; LIHC cis rs4908760 0.516 rs11121232 chr1:8850709 C/A cg20416874 chr1:8611966 RERE -0.57 -10.25 -0.48 1.15e-21 Vitiligo; LIHC trans rs7615952 0.688 rs7624806 chr3:125599074 G/A cg07211511 chr3:129823064 LOC729375 -0.8 -10.1 -0.48 3.78e-21 Blood pressure (smoking interaction); LIHC cis rs9303401 0.538 rs2240258 chr17:56458183 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.93 12.02 0.54 5.36e-28 Cognitive test performance; LIHC cis rs1707322 1.000 rs4660336 chr1:46487976 T/C cg06784218 chr1:46089804 CCDC17 -0.36 -6.47 -0.33 3.33e-10 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC cis rs11098499 0.863 rs12502389 chr4:120454191 A/G cg09307838 chr4:120376055 NA 0.77 11.79 0.54 3.73e-27 Corneal astigmatism; LIHC cis rs8014671 0.531 rs12880777 chr14:70874695 A/G cg25576086 chr14:70833871 SYNJ2BP -0.45 -7.05 -0.36 9.8e-12 Prostate cancer; LIHC cis rs7833790 0.700 rs7834483 chr8:82704828 A/G cg02079420 chr8:82753780 SNX16 0.34 6.18 0.32 1.86e-9 Diastolic blood pressure; LIHC cis rs1163251 0.837 rs592762 chr1:120247355 A/G cg19096424 chr1:120255104 PHGDH 0.63 8.1 0.4 9.82e-15 Blood metabolite levels; LIHC cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg18357526 chr6:26021779 HIST1H4A 0.43 6.45 0.33 3.82e-10 Height; LIHC cis rs9309473 0.528 rs11898362 chr2:73565293 G/A cg20560298 chr2:73613845 ALMS1 -0.46 -7.32 -0.37 1.82e-12 Metabolite levels; LIHC cis rs4332037 0.722 rs60346318 chr7:1915824 C/G cg23043544 chr7:2124092 MAD1L1 -0.42 -6.35 -0.32 6.92e-10 Bipolar disorder; LIHC cis rs2250402 0.510 rs2898984 chr15:40324075 G/C cg01081584 chr15:40268610 EIF2AK4 -0.52 -6.27 -0.32 1.11e-9 Corneal curvature; LIHC trans rs72829446 0.530 rs8075009 chr17:7374508 A/T cg08566640 chr11:64091735 NA -0.71 -6.55 -0.33 2.15e-10 Androgen levels; LIHC cis rs7799006 0.593 rs12531150 chr7:2289888 C/T cg02951883 chr7:2050386 MAD1L1 -0.4 -6.08 -0.31 3.23e-9 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); LIHC cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 0.9 13.89 0.6 4.4e-35 Alzheimer's disease; LIHC cis rs9467773 1.000 rs6456734 chr6:26566965 G/T cg11502198 chr6:26597334 ABT1 0.46 6.71 0.34 8.01e-11 Intelligence (multi-trait analysis); LIHC cis rs9560113 0.959 rs9560108 chr13:112180303 A/C cg14154082 chr13:112174009 NA 0.29 6.19 0.32 1.76e-9 Menarche (age at onset); LIHC trans rs1814175 0.615 rs10839378 chr11:49806943 C/T cg03929089 chr4:120376271 NA -0.84 -15.86 -0.65 7.63e-43 Height; LIHC cis rs12597458 0.789 rs7186207 chr16:72035359 C/T cg01557791 chr16:72042693 DHODH -0.72 -13.09 -0.58 4.92e-32 Prostate cancer; LIHC cis rs55665837 0.540 rs12416696 chr11:14790889 G/A cg16394018 chr11:14927549 NA 0.39 5.74 0.3 2.09e-8 Vitamin D levels; LIHC cis rs13191362 1.000 rs66534429 chr6:163003322 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.6 5.79 0.3 1.61e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); LIHC cis rs6960043 0.818 rs6947830 chr7:15064984 A/G cg19272540 chr7:15055459 NA 0.23 6.39 0.33 5.54e-10 Type 2 diabetes; LIHC cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.79 14.9 0.63 5.03e-39 Prudent dietary pattern; LIHC cis rs6430585 0.528 rs78274583 chr2:136734569 C/T cg07169764 chr2:136633963 MCM6 1.28 21.06 0.75 1.03e-63 Corneal structure; LIHC cis rs11098499 0.863 rs1383532 chr4:120434404 A/T cg09307838 chr4:120376055 NA -0.76 -12.01 -0.54 5.77e-28 Corneal astigmatism; LIHC cis rs858239 0.600 rs6978827 chr7:23125544 A/T cg23682824 chr7:23144976 KLHL7 0.46 6.86 0.35 3.19e-11 Cerebrospinal fluid biomarker levels; LIHC cis rs9902453 0.505 rs11080107 chr17:27938424 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.71 -11.27 -0.52 2.98e-25 Coffee consumption (cups per day); LIHC cis rs919433 0.519 rs700656 chr2:198653667 T/C cg00792783 chr2:198669748 PLCL1 0.46 6.83 0.35 3.97e-11 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); LIHC cis rs13108904 0.901 rs12509700 chr4:1296321 A/G cg16405210 chr4:1374714 KIAA1530 -0.42 -6.18 -0.32 1.83e-9 Obesity-related traits; LIHC cis rs7027203 0.797 rs3996254 chr9:96591239 A/G cg13679303 chr9:96623674 NA -0.3 -6.66 -0.34 1.08e-10 DNA methylation (variation); LIHC cis rs6964587 0.610 rs6465338 chr7:91450624 T/C cg17063962 chr7:91808500 NA 0.63 10.85 0.51 9.14e-24 Breast cancer; LIHC cis rs35110281 0.693 rs3819161 chr21:45092653 A/G cg01579765 chr21:45077557 HSF2BP -0.34 -5.88 -0.3 9.76e-9 Mean corpuscular volume; LIHC cis rs858239 0.509 rs6962213 chr7:23188109 G/A cg23682824 chr7:23144976 KLHL7 0.4 6.02 0.31 4.47e-9 Cerebrospinal fluid biomarker levels; LIHC cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg13607699 chr17:42295918 UBTF 0.47 7.55 0.38 3.96e-13 Total body bone mineral density; LIHC cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg05590025 chr7:65112418 INTS4L2 -0.64 -7.02 -0.35 1.22e-11 Diabetic kidney disease; LIHC cis rs939574 0.512 rs6730612 chr2:220146196 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.59 7.08 0.36 8.04e-12 Platelet distribution width; LIHC cis rs7267979 0.932 rs424487 chr20:25468131 C/G cg24626310 chr20:25276739 ABHD12;PYGB 0.46 6.83 0.35 3.79e-11 Liver enzyme levels (alkaline phosphatase); LIHC cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg03517284 chr6:25882590 NA 0.5 6.19 0.32 1.76e-9 Intelligence (multi-trait analysis); LIHC cis rs758324 0.947 rs4705903 chr5:131206594 A/C cg06307176 chr5:131281290 NA 0.42 6.11 0.31 2.7e-9 Alzheimer's disease in APOE e4- carriers; LIHC cis rs12594515 1.000 rs11855509 chr15:45995474 C/T cg19682013 chr15:45996608 NA 0.38 6.55 0.33 2.17e-10 Waist circumference;Weight; LIHC cis rs780096 0.525 rs13388159 chr2:27648284 A/T cg02592271 chr2:27665507 KRTCAP3 -0.43 -5.86 -0.3 1.09e-8 Total body bone mineral density; LIHC cis rs7772486 0.754 rs6570708 chr6:145989428 C/T cg23711669 chr6:146136114 FBXO30 -0.72 -12.98 -0.57 1.29e-31 Lobe attachment (rater-scored or self-reported); LIHC cis rs780096 0.565 rs813592 chr2:27721971 T/C cg17158414 chr2:27665306 KRTCAP3 -0.45 -6.11 -0.31 2.69e-9 Total body bone mineral density; LIHC cis rs12477438 0.822 rs6727170 chr2:99588042 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.71 -9.23 -0.45 3e-18 Chronic sinus infection; LIHC cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg23782820 chr8:58130467 NA 0.32 5.76 0.3 1.86e-8 Developmental language disorder (linguistic errors); LIHC cis rs1008375 0.931 rs6449310 chr4:17575530 T/C cg02297831 chr4:17616191 MED28 0.47 7.05 0.36 1e-11 Parasitemia in Tripanosoma cruzi seropositivity; LIHC cis rs10861342 1.000 rs11112373 chr12:105503708 G/A cg23923672 chr12:105501055 KIAA1033 0.65 7.64 0.38 2.27e-13 IgG glycosylation; LIHC trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg26668828 chr6:292823 DUSP22 0.59 8.19 0.4 5.16e-15 Menopause (age at onset); LIHC cis rs6582630 0.679 rs7301806 chr12:38596667 G/A cg26384229 chr12:38710491 ALG10B 0.43 6.48 0.33 3.26e-10 Drug-induced liver injury (flucloxacillin); LIHC trans rs7760535 0.656 rs7766190 chr6:111905066 A/G cg06045225 chr5:65892993 MAST4 0.39 6.18 0.32 1.86e-9 Metabolic traits; LIHC cis rs4906332 0.811 rs2021965 chr14:103997248 C/A cg19000871 chr14:103996768 TRMT61A 0.56 9.37 0.45 1.04e-18 Coronary artery disease; LIHC cis rs4906332 1.000 rs4900574 chr14:103879024 G/A cg26031613 chr14:104095156 KLC1 0.4 5.81 0.3 1.43e-8 Coronary artery disease; LIHC cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg22800045 chr5:56110881 MAP3K1 0.67 8.62 0.42 2.47e-16 Initial pursuit acceleration; LIHC cis rs4253772 0.591 rs8143066 chr22:46656607 C/T cg24881330 chr22:46731750 TRMU 0.55 5.9 0.3 8.9e-9 LDL cholesterol;Cholesterol, total; LIHC cis rs10489202 1.000 rs7520232 chr1:168011995 T/C cg17859187 chr1:168147929 TIPRL 0.46 5.74 0.3 2.12e-8 Schizophrenia; LIHC trans rs7395662 0.500 rs10838984 chr11:48640485 C/T cg03929089 chr4:120376271 NA -0.42 -6.44 -0.33 4.09e-10 HDL cholesterol; LIHC cis rs12620999 1.000 rs11689249 chr2:238083542 T/A cg23555395 chr2:238036564 NA -0.31 -5.84 -0.3 1.19e-8 Systemic lupus erythematosus; LIHC cis rs11718455 0.960 rs11917885 chr3:44008013 A/G cg08738300 chr3:44038990 NA -0.53 -9.42 -0.45 7.03e-19 Coronary artery disease; LIHC cis rs600806 0.683 rs10857788 chr1:110012289 G/A cg08911820 chr1:110026001 ATXN7L2 -0.63 -7.72 -0.39 1.25e-13 Intelligence (multi-trait analysis); LIHC cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg03517284 chr6:25882590 NA -0.68 -8.44 -0.42 8.94e-16 Intelligence (multi-trait analysis); LIHC cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg21433313 chr16:3507492 NAT15 0.46 8.28 0.41 2.74e-15 Tuberculosis; LIHC trans rs1005277 0.522 rs1208767 chr10:38042295 G/T cg27523141 chr10:43048294 ZNF37B 0.39 6.83 0.35 4e-11 Extrinsic epigenetic age acceleration; LIHC cis rs10791097 0.765 rs4622274 chr11:130729486 C/T cg09137382 chr11:130731461 NA 0.4 6.06 0.31 3.68e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs4911259 0.552 rs2014837 chr20:31461082 C/T cg13636640 chr20:31349939 DNMT3B 0.59 10.59 0.5 7.44e-23 Inflammatory bowel disease; LIHC cis rs888194 0.628 rs11609896 chr12:110038454 G/A cg05360138 chr12:110035743 NA 0.4 5.76 0.3 1.87e-8 Neuroticism; LIHC cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg11062466 chr8:58055876 NA 0.49 6.75 0.34 6.54e-11 Developmental language disorder (linguistic errors); LIHC cis rs4727027 0.899 rs11771339 chr7:148854132 A/T cg23583168 chr7:148888333 NA -0.74 -10.48 -0.49 1.83e-22 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg23242142 chr5:6633531 NSUN2;SRD5A1 0.47 6.12 0.31 2.62e-9 Lung function (FEV1/FVC); LIHC cis rs2658782 0.547 rs3020065 chr11:93059899 A/G cg15737290 chr11:93063684 CCDC67 0.46 5.96 0.31 6.13e-9 Pulmonary function decline; LIHC cis rs16958440 0.867 rs79231363 chr18:44665087 T/C cg17192377 chr18:44677553 HDHD2 0.62 6.75 0.34 6.32e-11 Sitting height ratio; LIHC trans rs2836974 0.613 rs2245455 chr21:40548087 A/T cg13692869 chr1:169336982 NME7;BLZF1 0.42 6.56 0.33 2.02e-10 Cognitive function; LIHC cis rs738322 0.967 rs6001038 chr22:38570585 A/G cg25457927 chr22:38595422 NA -0.26 -6.49 -0.33 2.99e-10 Cutaneous nevi; LIHC cis rs7613875 0.578 rs4688753 chr3:50074773 A/G cg21467203 chr3:49911342 NA 0.52 9.35 0.45 1.18e-18 Body mass index; LIHC cis rs4808199 0.948 rs2074300 chr19:19380996 G/T cg03709012 chr19:19516395 GATAD2A 0.98 15.57 0.64 1.09e-41 Nonalcoholic fatty liver disease; LIHC cis rs9790314 0.936 rs7629987 chr3:161002023 A/C cg03342759 chr3:160939853 NMD3 -0.74 -9.15 -0.44 5.12e-18 Morning vs. evening chronotype; LIHC cis rs6500602 0.561 rs62039231 chr16:4519548 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.5 7.76 0.39 1e-13 Schizophrenia; LIHC cis rs34779708 0.801 rs12246600 chr10:35538121 A/C cg03585969 chr10:35415529 CREM 0.78 11.48 0.53 4.98e-26 Inflammatory bowel disease;Crohn's disease; LIHC cis rs9814567 1.000 rs12637751 chr3:134266124 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 12.36 0.56 2.86e-29 Neurocognitive impairment in HIV-1 infection (dichotomous); LIHC cis rs2573652 1.000 rs2573652 chr15:100514614 A/G cg09918751 chr15:100517450 ADAMTS17 -0.78 -14.41 -0.61 4.23e-37 Height; LIHC cis rs10791097 0.690 rs12284540 chr11:130729772 T/C cg14779329 chr11:130786720 SNX19 0.38 5.87 0.3 1.05e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; LIHC cis rs1670533 1.000 rs7685541 chr4:1058501 G/A cg27284194 chr4:1044797 NA 0.6 8.97 0.44 1.93e-17 Recombination rate (females); LIHC cis rs4843747 0.605 rs4072779 chr16:88107290 C/T cg06050784 chr16:88016603 BANP 0.35 6.34 0.32 7.07e-10 Menopause (age at onset); LIHC cis rs739401 0.572 rs384490 chr11:3078885 A/C cg25174290 chr11:3078921 CARS 0.66 10.41 0.49 3.14e-22 Longevity; LIHC cis rs9611565 0.512 rs139560 chr22:42194962 A/G cg06634786 chr22:41940651 POLR3H -0.74 -7.52 -0.38 4.95e-13 Vitiligo; LIHC cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.5 7.86 0.39 5.2e-14 Prudent dietary pattern; LIHC cis rs9457247 0.967 rs377753 chr6:167389496 A/T cg23791538 chr6:167370224 RNASET2 -0.68 -11.7 -0.53 7.92e-27 Crohn's disease; LIHC cis rs7408868 1.000 rs10418305 chr19:15278808 C/G cg14696996 chr19:15285081 NOTCH3 0.54 7.08 0.36 8.26e-12 Pulse pressure; LIHC cis rs6429082 0.755 rs291372 chr1:235694106 G/C cg26050004 chr1:235667680 B3GALNT2 0.45 7.24 0.36 2.91e-12 Adiposity; LIHC trans rs9854771 0.507 rs4686529 chr3:189497616 A/G cg25802399 chr20:61847276 YTHDF1 -0.38 -6.06 -0.31 3.51e-9 Pancreatic cancer; LIHC cis rs600806 0.683 rs10857789 chr1:110012293 C/T cg23091122 chr1:110024289 SYPL2 -0.5 -6.78 -0.34 5.27e-11 Intelligence (multi-trait analysis); LIHC cis rs2273156 1.000 rs17102967 chr14:35480388 A/G cg16230307 chr14:35515116 FAM177A1 -0.42 -6.1 -0.31 2.9e-9 Immunoglobulin light chain (AL) amyloidosis; LIHC cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg20607798 chr8:58055168 NA 0.49 6.16 0.32 2.01e-9 Developmental language disorder (linguistic errors); LIHC cis rs7592578 0.771 rs4439990 chr2:191398353 A/C cg27211696 chr2:191398769 TMEM194B -0.63 -8.34 -0.41 1.81e-15 Diastolic blood pressure; LIHC cis rs4820294 0.669 rs12628135 chr22:38065655 A/G cg26138144 chr22:38071188 LGALS1 0.41 7.58 0.38 3.31e-13 Fat distribution (HIV); LIHC cis rs1552244 0.543 rs28719585 chr3:10050813 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -8.0 -0.4 1.93e-14 Alzheimer's disease; LIHC cis rs7208859 0.673 rs73263776 chr17:29211331 G/C cg13385521 chr17:29058706 SUZ12P 0.82 8.01 0.4 1.88e-14 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs523522 0.962 rs2233676 chr12:120933607 G/A cg12219531 chr12:120966889 COQ5 0.67 13.22 0.58 1.57e-32 High light scatter reticulocyte count; LIHC cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.91 8.72 0.43 1.21e-16 Platelet count; LIHC cis rs7937890 0.732 rs7946902 chr11:14273308 C/T cg19336497 chr11:14380999 RRAS2 0.39 6.64 0.34 1.23e-10 Mitochondrial DNA levels; LIHC cis rs6964587 0.839 rs6949881 chr7:91433827 C/T cg17063962 chr7:91808500 NA 0.96 17.21 0.68 2.88e-48 Breast cancer; LIHC cis rs6570726 0.791 rs10457788 chr6:145921136 T/A cg23711669 chr6:146136114 FBXO30 0.73 12.14 0.55 1.84e-28 Lobe attachment (rater-scored or self-reported); LIHC cis rs9322817 0.691 rs2400072 chr6:105344116 C/T cg02098413 chr6:105308735 HACE1 0.42 7.94 0.39 2.96e-14 Thyroid stimulating hormone; LIHC cis rs875971 0.660 rs801192 chr7:66031952 C/G cg18876405 chr7:65276391 NA -0.44 -7.7 -0.38 1.44e-13 Aortic root size; LIHC cis rs17401966 0.931 rs1002076 chr1:10438892 G/A cg19773385 chr1:10388646 KIF1B -0.39 -6.54 -0.33 2.23e-10 Hepatocellular carcinoma; LIHC cis rs9916302 0.904 rs650106 chr17:37451559 A/G cg00129232 chr17:37814104 STARD3 0.39 6.25 0.32 1.23e-9 Glomerular filtration rate (creatinine); LIHC cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg11494091 chr17:61959527 GH2 0.53 10.6 0.5 7.14e-23 Prudent dietary pattern; LIHC cis rs4665809 0.877 rs34536218 chr2:26287376 T/A cg04944784 chr2:26401820 FAM59B 0.59 6.42 0.33 4.45e-10 Gut microbiome composition (summer); LIHC cis rs6754311 0.608 rs3739020 chr2:136602491 T/G cg25344623 chr2:136566232 LCT -0.34 -6.57 -0.33 1.88e-10 Mosquito bite size; LIHC cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg18404041 chr3:52824283 ITIH1 -0.53 -8.73 -0.43 1.11e-16 Bipolar disorder; LIHC cis rs7264396 0.563 rs2425090 chr20:34304783 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.62 -8.7 -0.43 1.45e-16 Total cholesterol levels; LIHC cis rs2859741 1.000 rs2859741 chr1:37509352 C/T cg09363841 chr1:37513479 NA -0.2 -6.25 -0.32 1.25e-9 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); LIHC cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg17971929 chr21:40555470 PSMG1 0.81 9.67 0.46 1.06e-19 Cognitive function; LIHC cis rs600806 0.850 rs115935180 chr1:109976775 C/G cg02415029 chr1:110025642 ATXN7L2 -0.47 -5.94 -0.31 6.92e-9 Intelligence (multi-trait analysis); LIHC cis rs11583043 1.000 rs6682873 chr1:101470906 C/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.68 8.64 0.42 2.21e-16 Ulcerative colitis;Inflammatory bowel disease; LIHC cis rs2607426 0.681 rs2607413 chr19:41268214 C/T cg20631044 chr19:41255890 C19orf54;SNRPA -0.54 -6.39 -0.33 5.5e-10 Blood protein levels; LIHC cis rs6912958 0.559 rs107690 chr6:88069352 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.39 -7.73 -0.39 1.2e-13 Monocyte percentage of white cells; LIHC cis rs7503168 0.558 rs11870472 chr17:33872649 G/A cg20932281 chr17:33905541 PEX12 0.59 6.94 0.35 2.01e-11 Plateletcrit; LIHC cis rs2075165 0.935 rs933489 chr1:156235120 T/C cg20302342 chr1:156215951 PAQR6 0.35 6.74 0.34 6.8e-11 Tonsillectomy; LIHC cis rs7568458 0.527 rs35416445 chr2:85773659 A/G cg02493740 chr2:85810744 VAMP5 -0.48 -7.97 -0.4 2.43e-14 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); LIHC cis rs9811920 0.638 rs7629426 chr3:99652577 C/G cg21419939 chr3:99598918 C3orf26;FILIP1L;MIR548G -0.41 -5.81 -0.3 1.43e-8 Axial length; LIHC cis rs611744 0.870 rs429315 chr8:109094068 A/G cg21045802 chr8:109455806 TTC35 -0.51 -9.05 -0.44 1.13e-17 Dupuytren's disease; LIHC cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg13047869 chr3:10149882 C3orf24 0.54 6.52 0.33 2.5e-10 Alzheimer's disease; LIHC cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg02290350 chr8:58132656 NA 0.5 10.64 0.5 5.15e-23 Developmental language disorder (linguistic errors); LIHC cis rs10508774 1.000 rs12245906 chr10:33061079 C/A cg01819863 chr10:32635814 EPC1 0.63 5.78 0.3 1.68e-8 Peripheral arterial disease (traffic-related air pollution interaction); LIHC cis rs7107174 0.901 rs11237487 chr11:78126754 G/C cg02023728 chr11:77925099 USP35 0.41 7.41 0.37 9.96e-13 Testicular germ cell tumor; LIHC cis rs1580019 0.961 rs1610143 chr7:32498331 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.77 11.82 0.54 3e-27 Cognitive ability; LIHC cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg22618164 chr12:122356400 WDR66 0.57 8.24 0.41 3.84e-15 Mean corpuscular volume; LIHC trans rs875971 1.000 rs6970030 chr7:65968679 T/C cg10756647 chr7:56101905 PSPH 0.44 6.44 0.33 4.09e-10 Aortic root size; LIHC cis rs708547 0.533 rs3806746 chr4:57773330 C/T cg16868167 chr4:57843880 C4orf14;POLR2B -0.49 -7.04 -0.36 1.05e-11 Response to bleomycin (chromatid breaks); LIHC cis rs1401999 1.000 rs939338 chr3:183704068 A/G cg05044414 chr3:183734942 ABCC5 -0.33 -5.92 -0.31 7.68e-9 Anterior chamber depth; LIHC cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg10802521 chr3:52805072 NEK4 -0.45 -7.7 -0.38 1.49e-13 Electroencephalogram traits; LIHC cis rs4148883 0.645 rs2851264 chr4:100029715 C/T cg12011299 chr4:100065546 ADH4 0.37 7.39 0.37 1.11e-12 Alcohol dependence; LIHC trans rs803923 0.585 rs803917 chr9:119467660 A/G cg10829264 chr1:156024440 ROBLD3;UBQLN4 0.46 6.12 0.31 2.57e-9 Lung function (FEV1/FVC); LIHC cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg22963979 chr7:1858916 MAD1L1 -0.43 -6.85 -0.35 3.5e-11 Bipolar disorder and schizophrenia; LIHC cis rs34779708 0.733 rs11010146 chr10:35541561 T/A cg03585969 chr10:35415529 CREM 0.76 10.96 0.51 3.65e-24 Inflammatory bowel disease;Crohn's disease; LIHC cis rs12048904 1.000 rs12048904 chr1:101331536 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.53 -8.44 -0.42 9.38e-16 Multiple sclerosis; LIHC cis rs7959452 0.640 rs11177599 chr12:69721970 G/A cg14784868 chr12:69753453 YEATS4 0.87 16.72 0.67 2.77e-46 Blood protein levels; LIHC cis rs9303401 0.615 rs35288118 chr17:56600748 A/C cg25039879 chr17:56429692 SUPT4H1 0.81 9.04 0.44 1.16e-17 Cognitive test performance; LIHC cis rs244293 0.701 rs4793784 chr17:53038430 A/G cg19360675 chr17:53046073 COX11;STXBP4 -0.45 -6.17 -0.32 1.92e-9 Menarche (age at onset); LIHC cis rs4934494 0.635 rs12572869 chr10:91413368 C/T cg19698084 chr10:91461284 KIF20B -0.49 -6.49 -0.33 2.97e-10 Red blood cell count; LIHC cis rs57502260 0.915 rs7106320 chr11:68210118 C/T cg20283391 chr11:68216788 NA -0.47 -5.8 -0.3 1.55e-8 Total body bone mineral density (age 45-60); LIHC cis rs8017423 0.605 rs4904676 chr14:90819220 G/A cg04374321 chr14:90722782 PSMC1 -0.5 -7.26 -0.37 2.64e-12 Mortality in heart failure; LIHC cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg10712668 chr3:52740153 GLT8D1;SPCS1 0.51 7.22 0.36 3.35e-12 Bipolar disorder; LIHC cis rs9378688 0.654 rs62392609 chr6:2258345 A/C cg12303981 chr6:2244766 GMDS -0.45 -6.07 -0.31 3.41e-9 Caudate nucleus volume; LIHC cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.02 -10.44 -0.49 2.58e-22 Platelet count; LIHC cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg09455208 chr3:40491958 NA 0.4 8.25 0.41 3.44e-15 Renal cell carcinoma; LIHC cis rs155076 1.000 rs261369 chr13:21868420 C/A cg11317459 chr13:21872234 NA -0.91 -9.52 -0.46 3.1400000000000002e-19 White matter hyperintensity burden; LIHC trans rs208520 0.955 rs9453664 chr6:66976079 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.66 6.91 0.35 2.35e-11 Exhaled nitric oxide output; LIHC cis rs11166927 0.524 rs10092101 chr8:140830697 C/T cg16909799 chr8:140841666 TRAPPC9 -0.48 -7.68 -0.38 1.71e-13 Pediatric non-alcoholic fatty liver disease activity score; LIHC cis rs3824867 0.920 rs3740685 chr11:47468791 C/T cg20307385 chr11:47447363 PSMC3 0.6 8.17 0.4 6.14e-15 Mean corpuscular hemoglobin; LIHC cis rs12477438 0.520 rs36071868 chr2:99737120 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.93 14.69 0.62 3.12e-38 Chronic sinus infection; LIHC cis rs11718455 0.960 rs34019365 chr3:44004735 G/A cg08738300 chr3:44038990 NA 0.51 8.91 0.43 3.04e-17 Coronary artery disease; LIHC cis rs992157 1.000 rs11554825 chr2:219125809 C/T cg20019365 chr2:219134978 PNKD;AAMP 0.81 12.88 0.57 3.23e-31 Colorectal cancer; LIHC cis rs6089584 1.000 rs6089583 chr20:60563624 G/A cg06108461 chr20:60628389 TAF4 -0.88 -13.71 -0.6 2.16e-34 Body mass index; LIHC cis rs2274273 0.840 rs7144737 chr14:55822946 C/T cg01864836 chr14:55583639 NA -0.35 -6.14 -0.32 2.24e-9 Protein biomarker; LIHC cis rs7552404 0.655 rs1146646 chr1:76265500 G/A cg03433033 chr1:76189801 ACADM 0.62 8.39 0.41 1.29e-15 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs2303759 0.676 rs7248378 chr19:49908144 C/A cg22590775 chr19:49891494 CCDC155 0.47 7.65 0.38 2.04e-13 Multiple sclerosis; LIHC cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg05896524 chr21:47604654 C21orf56 0.5 7.95 0.4 2.68e-14 Testicular germ cell tumor; LIHC cis rs9326248 1.000 rs7107152 chr11:117056080 C/T cg11861562 chr11:117069780 TAGLN -0.47 -7.79 -0.39 7.89e-14 Blood protein levels; LIHC cis rs7551222 0.752 rs12039454 chr1:204542580 C/T cg20240347 chr1:204465584 NA 0.35 7.23 0.36 3.08e-12 Schizophrenia; LIHC cis rs6912958 0.500 rs4707352 chr6:87929705 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.6 -11.18 -0.52 6.2e-25 Monocyte percentage of white cells; LIHC cis rs1577917 0.771 rs9353318 chr6:86231721 T/A cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.48 8.39 0.41 1.32e-15 Response to antipsychotic treatment; LIHC cis rs2991971 1.000 rs2991972 chr1:46013208 C/T cg03146154 chr1:46216737 IPP -0.39 -5.93 -0.31 7.45e-9 High light scatter reticulocyte count; LIHC cis rs9640161 0.830 rs3735165 chr7:150068371 T/C cg17279839 chr7:150038598 RARRES2 0.39 7.92 0.39 3.39e-14 Blood protein levels;Circulating chemerin levels; LIHC cis rs4950322 0.512 rs2353974 chr1:146856256 A/G cg25205988 chr1:146714368 CHD1L 0.42 6.03 0.31 4.25e-9 Protein quantitative trait loci; LIHC cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg00825309 chr19:58991885 ZNF446 -0.53 -8.34 -0.41 1.79e-15 Uric acid clearance; LIHC cis rs12926788 0.542 rs11862971 chr16:24767574 C/A cg00339695 chr16:24857497 SLC5A11 0.73 11.09 0.51 1.23e-24 Ejection fraction in Tripanosoma cruzi seropositivity; LIHC cis rs17376456 0.825 rs10056879 chr5:93282218 C/A cg25358565 chr5:93447407 FAM172A 1.1 9.73 0.47 6.68e-20 Diabetic retinopathy; LIHC cis rs1062177 1.000 rs17804178 chr5:151197729 T/G cg00977110 chr5:151150581 G3BP1 0.54 6.9 0.35 2.53e-11 Preschool internalizing problems; LIHC cis rs7944584 0.511 rs10838725 chr11:47557871 T/C cg20307385 chr11:47447363 PSMC3 1.01 16.48 0.67 2.56e-45 Fasting blood glucose;Fasting blood glucose (BMI interaction); LIHC trans rs729050 0.851 rs2402317 chr14:94077336 A/G cg00587042 chr7:42927968 NA -0.44 -6.04 -0.31 4.1e-9 Body mass index; LIHC trans rs7618501 0.633 rs2526748 chr3:50080439 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.57 -9.34 -0.45 1.3e-18 Intelligence (multi-trait analysis); LIHC cis rs243505 0.762 rs933436 chr7:148487329 A/C cg09806900 chr7:148480153 CUL1 -0.45 -6.86 -0.35 3.27e-11 Inflammatory bowel disease;Crohn's disease; LIHC cis rs6942756 0.531 rs7811141 chr7:128908273 C/G cg02491457 chr7:128862824 NA 0.58 9.48 0.46 4.35e-19 White matter hyperintensity burden; LIHC cis rs2832191 0.632 rs2246777 chr21:30309586 T/C cg08807101 chr21:30365312 RNF160 -0.77 -11.1 -0.51 1.18e-24 Dental caries; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05970768 chr5:171682616 UBTD2 0.44 6.21 0.32 1.56e-9 Hepatitis; LIHC trans rs60843830 1.000 rs3791221 chr2:226933 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.66 9.32 0.45 1.47e-18 Spherical equivalent (joint analysis main effects and education interaction); LIHC cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg05368731 chr17:41323189 NBR1 0.72 12.48 0.56 9.96e-30 Menopause (age at onset); LIHC cis rs2549003 0.966 rs10072571 chr5:131816711 A/C cg21138405 chr5:131827807 IRF1 0.37 9.6 0.46 1.71e-19 Asthma (sex interaction); LIHC cis rs3820500 0.543 rs1290552 chr1:118054772 G/T cg20383390 chr1:117909022 MAN1A2 0.45 5.89 0.3 9.21e-9 Pneumonia; LIHC trans rs1005277 0.579 rs2800485 chr10:38542588 G/A cg04469686 chr1:162760199 HSD17B7 -0.39 -6.04 -0.31 4.12e-9 Extrinsic epigenetic age acceleration; LIHC cis rs898097 0.841 rs8074284 chr17:80909967 G/A cg15664640 chr17:80829946 TBCD 0.66 10.61 0.5 6.13e-23 Breast cancer; LIHC cis rs9297145 0.761 rs62473015 chr7:98763301 G/A cg05967295 chr7:98741636 SMURF1 0.73 10.38 0.49 4.11e-22 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; LIHC cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg25072359 chr17:41440525 NA 0.37 5.81 0.3 1.4e-8 Menopause (age at onset); LIHC cis rs7208859 0.673 rs216418 chr17:28936537 G/A cg14067834 chr17:29058358 SUZ12P 0.6 6.36 0.33 6.6e-10 Mean corpuscular hemoglobin;Mean corpuscular volume; LIHC cis rs11997175 0.603 rs4739382 chr8:33807012 C/T ch.8.33884649F chr8:33765107 NA 0.41 6.76 0.34 6.1e-11 Body mass index; LIHC cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg06634786 chr22:41940651 POLR3H -0.8 -8.8 -0.43 7.12e-17 Vitiligo; LIHC cis rs6545977 0.531 rs2539981 chr2:63104904 T/C cg17519650 chr2:63277830 OTX1 0.66 10.99 0.51 2.84e-24 Prostate cancer; LIHC cis rs6450176 0.638 rs56220547 chr5:53287952 A/G ch.5.1024479R chr5:53302184 ARL15 -0.98 -17.43 -0.69 4.03e-49 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; LIHC cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg07061783 chr6:25882402 NA 0.64 8.47 0.42 7.6e-16 Blood metabolite levels; LIHC cis rs6963495 0.818 rs73190184 chr7:105163736 C/T cg19920283 chr7:105172520 RINT1 0.69 6.55 0.33 2.17e-10 Bipolar disorder (body mass index interaction); LIHC cis rs10504229 0.906 rs2270609 chr8:58194684 G/A cg02290350 chr8:58132656 NA 0.44 8.72 0.43 1.21e-16 Developmental language disorder (linguistic errors); LIHC cis rs5753618 0.561 rs13054220 chr22:31704492 A/G cg22777020 chr22:31556080 RNF185 0.55 6.35 0.32 6.77e-10 Colorectal cancer; LIHC cis rs9467773 1.000 rs9393731 chr6:26529374 C/T cg09904177 chr6:26538194 HMGN4 0.66 13.74 0.6 1.57e-34 Intelligence (multi-trait analysis); LIHC cis rs6750047 0.585 rs4670235 chr2:38272528 C/T cg07380506 chr2:38303506 CYP1B1 0.58 7.44 0.37 8.17e-13 Cutaneous malignant melanoma;Melanoma; LIHC cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg12379764 chr21:47803548 PCNT -0.55 -8.15 -0.4 7.02e-15 Testicular germ cell tumor; LIHC cis rs1461503 0.934 rs7113330 chr11:122843358 C/T cg25161029 chr11:122845972 NA 0.33 5.81 0.3 1.41e-8 Menarche (age at onset); LIHC cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg08132940 chr7:1081526 C7orf50 -0.81 -6.84 -0.35 3.6e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); LIHC cis rs2732480 0.500 rs1552550 chr12:48643351 C/A cg21466736 chr12:48725269 NA -0.71 -10.87 -0.51 7.92e-24 Hemoglobin concentration;Red blood cell count;Hematocrit; LIHC cis rs2370759 1.000 rs16933177 chr10:32565705 G/A cg18270830 chr10:32634957 EPC1 0.54 6.61 0.34 1.46e-10 Sexual dysfunction (female); LIHC cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg02564969 chr6:151773285 C6orf211;RMND1 0.54 8.36 0.41 1.65e-15 Menarche (age at onset); LIHC cis rs459571 0.920 rs417142 chr9:136891370 G/T cg13789015 chr9:136890014 NCRNA00094 0.46 8.44 0.42 8.97e-16 Platelet distribution width; LIHC cis rs7428 0.527 rs4832164 chr2:85546932 A/C cg24342717 chr2:85555507 TGOLN2 -0.79 -10.38 -0.49 3.97e-22 Ear protrusion; LIHC cis rs2243480 0.901 rs778732 chr7:65822360 C/T cg05590025 chr7:65112418 INTS4L2 -0.56 -6.12 -0.31 2.62e-9 Diabetic kidney disease; LIHC cis rs4727027 0.651 rs12704068 chr7:148856153 T/C cg23583168 chr7:148888333 NA -0.71 -9.18 -0.44 4.24e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; LIHC cis rs875971 1.000 rs7801282 chr7:65613687 C/T cg11764359 chr7:65958608 NA -0.88 -15.36 -0.64 7.22e-41 Aortic root size; LIHC cis rs4819052 0.851 rs28501512 chr21:46676702 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 7.91 0.39 3.69e-14 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; LIHC cis rs9733 0.744 rs12125650 chr1:150760174 A/G cg13175981 chr1:150552382 MCL1 0.49 7.11 0.36 6.71e-12 Tonsillectomy; LIHC cis rs8060686 0.545 rs3815173 chr16:68160289 T/G cg05110241 chr16:68378359 PRMT7 -0.63 -6.99 -0.35 1.45e-11 HDL cholesterol;Metabolic syndrome; LIHC cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg05552183 chr6:42928497 GNMT 0.68 10.11 0.48 3.3e-21 Alzheimer's disease in APOE e4+ carriers; LIHC cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg05590025 chr7:65112418 INTS4L2 0.61 6.78 0.34 5.22e-11 Diabetic kidney disease; LIHC cis rs9911578 0.904 rs7209253 chr17:56908987 C/T cg12560992 chr17:57184187 TRIM37 0.96 17.37 0.68 6.51e-49 Intelligence (multi-trait analysis); LIHC cis rs7793919 0.652 rs10228886 chr7:4783224 C/T cg09789173 chr7:4769017 FOXK1 -0.62 -9.18 -0.44 4.29e-18 Mosquito bite size; LIHC trans rs561341 1.000 rs530715 chr17:30320544 T/G cg20587970 chr11:113659929 NA -1.23 -10.64 -0.5 5.12e-23 Hip circumference adjusted for BMI; LIHC cis rs6964587 1.000 rs1859037 chr7:91568272 A/G cg17063962 chr7:91808500 NA -1.02 -19.52 -0.73 1.47e-57 Breast cancer; LIHC cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg08280861 chr8:58055591 NA 0.49 6.03 0.31 4.2e-9 Developmental language disorder (linguistic errors); LIHC cis rs909002 0.849 rs10753257 chr1:32086089 G/A cg13919466 chr1:32135498 COL16A1 -0.33 -6.3 -0.32 9.18e-10 Intelligence (multi-trait analysis); LIHC cis rs7909074 0.509 rs2183994 chr10:45389940 T/C cg04218760 chr10:45406644 TMEM72 -0.21 -6.29 -0.32 9.72e-10 Mean corpuscular volume; LIHC trans rs1432133 0.844 rs12899579 chr15:27224321 C/T cg05810949 chr17:17740344 SREBF1 0.45 6.04 0.31 4.11e-9 Hepatitis; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg10193671 chr17:79846205 THOC4 0.45 6.86 0.35 3.32e-11 Longevity; LIHC cis rs11105298 0.891 rs10858903 chr12:89927972 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -7.48 -0.37 6.4e-13 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; LIHC cis rs9527 0.830 rs10883790 chr10:104640955 A/C cg15744005 chr10:104629667 AS3MT -0.34 -6.73 -0.34 7.2e-11 Arsenic metabolism; LIHC cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg11070056 chr1:107600091 PRMT6 0.69 12.09 0.55 2.83e-28 Facial morphology (factor 21, depth of nasal alae); LIHC cis rs12497850 0.864 rs12493001 chr3:49181885 A/G cg16497277 chr3:49208875 KLHDC8B -0.48 -5.77 -0.3 1.78e-8 Parkinson's disease; LIHC cis rs6918586 0.594 rs198842 chr6:26111448 C/T cg18357526 chr6:26021779 HIST1H4A -0.56 -8.22 -0.41 4.13e-15 Schizophrenia; LIHC cis rs35306767 0.855 rs11253499 chr10:944090 A/C cg20503657 chr10:835505 NA 1.04 11.92 0.54 1.23e-27 Eosinophil percentage of granulocytes; LIHC cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.6 8.5 0.42 5.85e-16 Lymphocyte counts; LIHC cis rs904251 0.828 rs1757178 chr6:37486310 C/T cg01843034 chr6:37503916 NA 0.49 7.77 0.39 8.98e-14 Cognitive performance; LIHC cis rs9902453 0.868 rs9902340 chr17:28476458 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.65 -10.26 -0.49 1.04e-21 Coffee consumption (cups per day); LIHC trans rs2117032 0.659 rs4762694 chr12:21176987 A/G cg14929913 chr10:1147979 WDR37 0.47 7.0 0.35 1.33e-11 Bilirubin levels; LIHC cis rs2842992 0.789 rs9355748 chr6:160194882 G/A cg19482086 chr6:160211437 TCP1;MRPL18 0.69 12.15 0.55 1.77e-28 Age-related macular degeneration (geographic atrophy); LIHC cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg10802521 chr3:52805072 NEK4 -0.44 -7.28 -0.37 2.27e-12 Bipolar disorder; LIHC cis rs427394 1.000 rs274672 chr5:6744176 G/A cg10857441 chr5:6722123 POLS -0.35 -5.97 -0.31 5.87e-9 Menopause (age at onset); LIHC cis rs12644436 0.711 rs1381951 chr4:88788592 T/C cg06891869 chr4:88767617 MEPE 0.42 7.6 0.38 2.93e-13 HIV-1 viral setpoint; LIHC cis rs1003719 0.715 rs8128387 chr21:38556787 G/C cg10648535 chr21:38446584 PIGP;TTC3 -0.7 -10.72 -0.5 2.65e-23 Eye color traits; LIHC cis rs6952808 0.501 rs3778999 chr7:2180885 G/A cg20295408 chr7:1910781 MAD1L1 -0.39 -5.73 -0.3 2.21e-8 Bipolar disorder and schizophrenia; LIHC cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg18305652 chr10:134549665 INPP5A 0.43 6.2 0.32 1.63e-9 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); LIHC cis rs10504229 0.953 rs59034808 chr8:58185337 T/C cg21724239 chr8:58056113 NA 0.46 6.08 0.31 3.23e-9 Developmental language disorder (linguistic errors); LIHC cis rs3793683 0.965 rs3829131 chr10:134564627 A/G cg18305652 chr10:134549665 INPP5A -0.38 -6.1 -0.31 2.94e-9 Migraine; LIHC trans rs3780486 0.505 rs10813958 chr9:33165985 A/G cg04842962 chr6:43655489 MRPS18A 0.81 15.21 0.64 2.87e-40 IgG glycosylation; LIHC cis rs9768139 0.683 rs28682392 chr7:158116004 A/G cg06219351 chr7:158114137 PTPRN2 -0.21 -5.91 -0.3 8.29e-9 Calcium levels; LIHC cis rs36207871 1 rs36207871 chr12:56684496 TAGGAA/T cg26734620 chr12:56694298 CS -0.98 -9.97 -0.47 9.97e-21 Inflammatory skin disease; LIHC cis rs2304069 0.779 rs245081 chr5:149356075 G/T cg22760475 chr5:149380129 HMGXB3;TIGD6 0.67 9.12 0.44 6.73e-18 HIV-1 control; LIHC cis rs2066819 1.000 rs76466034 chr12:56719450 G/A cg26734620 chr12:56694298 CS 1.3 11.32 0.52 1.99e-25 Psoriasis vulgaris; LIHC cis rs7552404 0.961 rs211710 chr1:76109038 G/A cg03433033 chr1:76189801 ACADM -0.68 -9.57 -0.46 2.21e-19 Blood metabolite levels;Acylcarnitine levels; LIHC cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg18230493 chr5:56204884 C5orf35 -0.41 -5.8 -0.3 1.55e-8 Initial pursuit acceleration; LIHC cis rs9486719 0.948 rs11152970 chr6:96909077 A/G cg06623918 chr6:96969491 KIAA0776 -0.66 -6.81 -0.35 4.32e-11 Migraine;Coronary artery disease; LIHC cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg19318889 chr4:1322082 MAEA -0.62 -10.41 -0.49 3.27e-22 Longevity; LIHC cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -7.51 -0.38 5.12e-13 Lymphocyte counts; LIHC cis rs138777 0.927 rs2235148 chr22:35664941 T/C cg02285386 chr22:35695157 TOM1 0.35 5.76 0.3 1.92e-8 Cholesterol, total;Total cholesterol levels; LIHC cis rs1707322 0.752 rs11211171 chr1:46168642 A/G cg06784218 chr1:46089804 CCDC17 0.41 7.19 0.36 4.14e-12 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); LIHC trans rs7874142 0.666 rs3811162 chr9:137688427 T/G cg18109838 chr5:88185987 MEF2C -0.39 -7.58 -0.38 3.21e-13 Longevity; LIHC cis rs295140 0.506 rs4673855 chr2:201136143 A/G cg23649088 chr2:200775458 C2orf69 -0.47 -6.57 -0.33 1.91e-10 QT interval; LIHC cis rs68170813 0.559 rs74774133 chr7:106941449 T/C cg02696742 chr7:106810147 HBP1 -0.5 -5.83 -0.3 1.29e-8 Coronary artery disease; LIHC cis rs7674212 0.541 rs2720464 chr4:104073201 G/A cg16532752 chr4:104119610 CENPE -0.41 -6.49 -0.33 3.09e-10 Type 2 diabetes; LIHC cis rs1801251 1.000 rs283471 chr2:233656627 G/A cg08000102 chr2:233561755 GIGYF2 0.77 11.7 0.53 7.84e-27 Coronary artery disease; LIHC cis rs970821 0.667 rs13276451 chr8:124746692 A/G cg00283535 chr8:124749564 ANXA13 0.41 7.47 0.37 6.67e-13 Breast cancer; LIHC cis rs9918079 0.506 rs10214 chr4:15606431 T/C cg16509355 chr4:15471240 CC2D2A 0.47 7.38 0.37 1.23e-12 Obesity-related traits; LIHC cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg07167872 chr1:205819463 PM20D1 0.6 8.68 0.42 1.67e-16 Menarche (age at onset); LIHC cis rs9733 0.519 rs11807450 chr1:150677719 C/T cg13175981 chr1:150552382 MCL1 -0.42 -5.72 -0.3 2.28e-8 Tonsillectomy; LIHC cis rs751728 0.931 rs2296746 chr6:33744711 C/T cg25922239 chr6:33757077 LEMD2 0.45 7.57 0.38 3.56e-13 Crohn's disease; LIHC cis rs6500602 0.647 rs1659497 chr16:4594635 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.43 -6.46 -0.33 3.63e-10 Schizophrenia; LIHC cis rs72781680 1.000 rs72798408 chr2:24181845 G/C cg08917208 chr2:24149416 ATAD2B 0.95 8.21 0.41 4.55e-15 Lymphocyte counts; LIHC cis rs2439831 0.850 rs28524541 chr15:44124831 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.54 6.69 0.34 9.05e-11 Lung cancer in ever smokers; LIHC cis rs1577917 0.771 rs4419647 chr6:86225739 T/C cg20289299 chr6:86388069 SNHG5;SNORD50B;SNORD50A 0.48 8.39 0.41 1.32e-15 Response to antipsychotic treatment; LIHC cis rs34779708 0.966 rs11010135 chr10:35518063 A/G cg04310649 chr10:35416472 CREM -0.44 -5.85 -0.3 1.13e-8 Inflammatory bowel disease;Crohn's disease; LIHC cis rs10504229 0.817 rs60646469 chr8:58195348 T/C cg02290350 chr8:58132656 NA 0.47 9.18 0.44 4.15e-18 Developmental language disorder (linguistic errors); LIHC cis rs870825 0.929 rs72689262 chr4:185590950 C/G cg04058563 chr4:185651563 MLF1IP 0.78 6.53 0.33 2.35e-10 Blood protein levels; LIHC cis rs7106204 0.748 rs6484028 chr11:24222438 A/G ch.11.24196551F chr11:24239977 NA 0.78 10.68 0.5 3.74e-23 Response to Homoharringtonine (cytotoxicity); LIHC cis rs796364 0.806 rs74724807 chr2:201005109 A/C cg25936922 chr2:200820526 C2orf60;C2orf47 -0.62 -6.75 -0.34 6.25e-11 Schizophrenia; LIHC cis rs2708977 0.933 rs2579502 chr2:97198800 A/G cg01950434 chr2:97203154 ARID5A -0.54 -8.15 -0.4 7.06e-15 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; LIHC trans rs2031577 0.710 rs10904169 chr10:4061039 C/T cg09681706 chr7:75703103 NA 0.45 6.53 0.33 2.37e-10 Longevity; LIHC cis rs1790761 0.505 rs6591256 chr11:67349899 A/G cg21734168 chr11:67353974 GSTP1 0.25 5.78 0.3 1.68e-8 Mean corpuscular volume; LIHC cis rs3806843 0.900 rs2563286 chr5:140125199 T/A cg19875535 chr5:140030758 IK -0.36 -6.01 -0.31 4.76e-9 Depressive symptoms (multi-trait analysis); LIHC cis rs11122272 0.705 rs2486742 chr1:231507254 G/A cg06096015 chr1:231504339 EGLN1 0.5 9.46 0.46 5.31e-19 Hemoglobin concentration; LIHC cis rs7107174 1.000 rs10899454 chr11:77997513 T/C cg02023728 chr11:77925099 USP35 0.5 9.57 0.46 2.15e-19 Testicular germ cell tumor;